bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effectiveness of organisational-level workplace mental health interventions on mental health and wellbeing in construction workers: A systematic review and recommended research agenda
Authors: Greiner Birgit A. , Leduc Caleb , O’Brien Cliodhna , Cresswell-Smith Johanna , Rugulies Reiner , Wahlbeck Kristian , Abdulla Kahar , Amann Benedikt L. , Pashoja Arlinda Cerga , Coppens Evelien , Corcoran Paul , Maxwell Margaret , Ross Victoria , de Winter Lars , Arensman Ella , Aust Birgit 
Published: November 2022

Objectives
This systematic review assesses the scientific evidence regarding the effectiveness of organisational-level workplace mental health interventions on stress, burnout, non-clinical depressive and anxiety symptoms, and wellbeing in construction workers.

Methods
Eligibility criteria were randomized controlled trials (RCTs), cluster randomized controlled trials (cRCTs), controlled or uncontrolled before- and after studies published in peer-reviewed journals between 2010 and May 2022 in five databases (Academic Search Complete, PsycInfo, PubMed, Scopus and Web of Science). Outcomes were stress, burnout and non-clinical depression and anxiety symptoms, and wellbeing (primary) and workplace changes and sickness absenteeism (secondary). Quality appraisal was conducted using the QATQS scale, a narrative synthesis was applied. The protocol was published in PROSPERO CRD42020183640 https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020183640.

Main results
We identified five articles (four studies) with a total sample size of 260, one cRCT, one controlled before- and after study, and two uncontrolled before- and after studies. The methodological quality of one study was rated as moderate, while for three studies it was weak. One study showed significant effects of a work redesign programme in short-term physiological stress parameters, one study showed a significant employee perceived improvement of information flow after supervisor training and one study showed a substantial non-significant decline in sick leave. There was no significant effect on general mental health (SF12) nor on emotional exhaustion. The focus of all studies was on physical health, while detailed mental health and wellbeing measures were not applied.

Main conclusions
The evidence for the effectiveness of organisational-level workplace mental health interventions in construction workers is limited with opportunities for methodological and conceptual improvement. Recommendations include the use of a wider range of mental health and wellbeing outcomes, interventions tailored to the specific workplace and culture in construction and the application of the principles of complex interventions in design and evaluation.
Extensão e comunicação
Authors: Brutscher Volmir José , Pereira Ana Maria Sotero , Nunes Cleiton de Barros 
Published: November 2022

O objetivo do relato é sistematizar a experiência do Núcleo Educação, Trabalho e Movimentos Sociais, da Universidade de Pernambuco, lançando luz sobre o próprio processo. A metodologia se orienta pela análise dialética, que consiste em analisar e compreender a realidade em relação ao todo, em processo histórico e, portanto, em movimento. Apoia-se na concepção de educação popular contemporânea, tendo em Paulo Freire a principal referência teórica. Como resultado, indica algumas categorias que expressam a realidade e o desejo do Núcleo, a saber: o diálogo, a participação, o estar e o aprender com, a consciência de classe, o sonho e a esperança. Como conclusão, aponta para um processo organizativo que assume a dimensão política da educação, tomando posição ao lado dos trabalhadores e dos movimentos populares, na luta por emancipação e transformação.
Úroveň syndrómu vyhorenia a pohľad učiteľov na distančné vzdelávanie počas pandémie Covid-19 na Slovensku
Authors: Kohútová Katarína 
Published: November 2022

Cieľom príspevku je identifikovať úroveň syndrómu vyhorenia učiteľov na Slovensku počas distančnej formy vyučovania a zároveň zmapovať skúsenosti a prežívanie učiteľov počas spomínanej formy vyučovania.
Metódy: K výskumným metódam patril Dotazník syndrómu vyhorenia MBI-ED a otvorené otázky. Získané dáta boli analyzované prostredníctvom štatistickej analýzy a kvalitatívneho kódovania.
Výsledky: Štatistická analýza ukázala, že najmä učitelia na druhom stupni základných škôl a stredoškolskí učitelia sú rizikoví z hľadiska syndrómu vyhorenia a jeho ďalšieho prehlbovania. Kvalitatívna analýza odhalila faktory, ktoré učitelia počas distančnej formy vyučovania hodnotili pozitívne i negatívne.
Závery: Determinantom, ktorý pôsobil na vyčerpanie učiteľov počas distančnej formy vyučovania bolo spojenie dvoch faktorov: a) zvýšenie náročnosti na prípravu na vyučovanie a b) nezáujem až ľahostajnosť žiakov k vyučovaciemu procesu. 19 % učiteľov trpí vysokým stupňom syndrómu vyhorenia vo všetkých jeho faktoroch.
(Ne)úspěšné nastartování počátečního čtení
Authors: Nováková Schöffelová Miroslava , Al Haboubi Lucie 
Published: November 2022

Zralost a připravenost dětí na školu je velkým tématem učitelské i rodičovské populace. Odborné kruhy diskutují o důležitosti jednotlivých složek školní připravenosti z různých úhlů pohledu. V tomto článku se zaměřujeme na připravenost dětí na čtení. Popisujeme a objasňujeme proces čtení jakožto dovednost vyžadující přípravu a určitý stupeň zvládnutí dovedností, které čtení předcházejí. Tyto dovednosti zasazujeme do kontextu psycholingvistického přístupu. Článek představuje, jaké dovednosti jsou podle tohoto přístupu důležité pro počáteční čtení, a na českých dostupných datech ukazuje, zda a jak dalece těmito dovednostmi děti na počátku čtení disponují. Dále předkládáme výzkumnou studii – obsahovou analýzu přípravného období učebnic počátečního čtení. Cílem studie bylo kvantifikovat a kvalitativně zhodnotit úlohy rozvíjející jednu z dovedností definovaných v úvodní části jako klíčovou pro počáteční čtení (konkrétně fonologické, resp. fonematické uvědomování). Metodou výzkumu je obsahová analýza učebnic počátečního čtení (živých abeced), v prvním kroku přípravného období, ve druhém kroku momentu seznámení s prvním grafémem. Výsledky poukazují na to, že zastoupení této oblasti v přípravném období živých abeced je minimální. Diskuse zasazuje zjištění do kontextu předškolního vzdělávání a navrhuje řešení, které by přineslo lepší kontinuitu v přechodu od preprimárního vzdělávání k primárnímu v oblasti čtení.
Green synthesis of magnetic activated carbon from peanut shells functionalized with TiO2 photocatalyst for Batik liquid waste treatment
Authors: Utami Maisari , Zahra’ Hasna’ Azizah , Khoirunisa  , Dewi Tania Amara 
Published: November 2022

Abstract
The composite of magnetic activated carbon derived from peanut shells functionalized titanium dioxide (Fe3O4/TiO2/AC) has been successfully synthesized. The composite was employed to remove indigosol green and Cr(vi) under ultraviolet (UV) and visible light. In this work, the activated carbon was synthesized from a sustainable source of peanut shell by carbonization and activation method employing NaOH as the activating agent. Magnetite was prepared by chemical co-precipitation technique using FeCl3·6H2O and FeSO4·7H2O, and then, the deposition of TiO2 was performed under ultrasonic irradiation. A variety of material characterization, consisting of Fourier transform infrared, X-ray diffraction, and scanning electron microscopy-energy dispersive X-ray, was used to analyze the physicochemical properties of the composite. The effects of pH, irradiation time, and composite mass during optimization performance were investigated. The characterizations represent the dispersed TiO2 in the anatase phase with the existence of magnetic particles. The activity tests revealed the superiority of the composite for applications involving adsorption and photocatalysis under visible light source compared to UV light. It was found that Fe3O4/TiO2/AC yields the efficiency for the removal of indigosol green and Cr(vi) from Batik liquid waste of 92.91 and 76.92%, respectively.
Alexander of Aphrodisias’ Criticism of the Stoic Theory of Perception:typosandtypōsis
Authors: Hangai Attila 
Published: November 2022

AbstractThe Stoics identified thephantasiawith the impression (typos) in the soul, or the impressing process (typōsis). Alexander of Aphrodisias engages directly with this account atDe anima68.10–21, and argues against the applicability of the impression in a theory of perception inMantissa10, especially 133.25–134.23. I analyse Alexander’s polemic account atDe anima68.10–21, I demonstrate that it differs from Chrysippus’ criticism of Cleanthes (contrary to some commentators), and I show how it fits in the context of his argument. From this analysis it will emerge how Alexander uses Stoic ideas to form his Aristotelian account. Then, I show that Alexander, by taking ‘typos’ metaphorically, not only prefers the term ‘enkataleimma’ over ‘typos’ in his theory ofphantasia, but he keeps the ‘typos’ terminology only to remain faithful to Aristotle’s use (contrary to some commentators).
Reactions of 3-amino-1,2,4-triazine with coupling reagents and electrophiles
Authors: Bvumbi Mpelegeng Victoria , Nemudzivhadi Anza Imanuel , Sengane Musiiwa Victoria , Moleele Simon Mnyakeni 
Published: November 2022

Abstract
Analogs of a new heterocyclic system were obtained from the reactions of 3-amino-1,2,4-triazine with coupling reagents such as boronic acids, and terminal alkynes in the presence of a palladium catalyst. Other reactions such as amination of the triazine at position 5, followed by electrophilic reactions with phenyl isocyanates and benzoyl chlorides, were performed to form new monoureido and benzoylated compounds.
American peacetime naval aviation and the Battle of Midway
Authors: McGregor Steven 
Published: November 2022

Abstract
There are many explanations for the victory of the United States against the Japanese at the Battle of Midway on June 4, 1942. Mistakes made by the Japanese certainly factored in the outcome and the United States also had certain advantages. However, an important if not sufficient explanation for the US victory is the pre-war preparation of the US Navy during peacetime. Designed by Ed Heinemann at Douglas Aircraft in El Segundo, California, from 1934 until 1938, the first Dauntless planes were delivered to the navy in 1940, well in advance of the Japanese attack on Pearl Harbor, the moment which is conventionally regarded as the US entry into the war. The pilots of the Dauntless, as I will show in this essay, were much the same; they too were the product of a peacetime Navy.
Selective TLR4 Antagonism Prevents and Reverses Morphine-Induced Persistent Postoperative Cognitive Dysfunction, Dysregulation of Synaptic Elements, and Impaired BDNF Signaling in Aged Male Rats
Authors: Muscat Stephanie M. , Deems Nicholas P. , Butler Michael J. , Scaria Emmanuel A. , Bettes Menaz N. , Cleary Sean P. , Bockbrader Ross H. , Maier Steven F. , Barrientos Ruth M. 
Published: November 2022

Perioperative neurocognitive disorders (PNDs) are characterized by confusion, difficulty with executive function, and episodic memory impairment in the hours to months following a surgical procedure. Postoperative cognitive dysfunction (POCD) represents such impairments that last beyond 30 d postsurgery and is associated with increased risk of comorbidities, progression to dementia, and higher mortality. While it is clear that neuroinflammation plays a key role in PND development, what factors underlie shorter self-resolving versus persistent PNDs remains unclear. We have previously shown that postoperative morphine treatment extends POCD from 4 d (without morphine) to at least 8 weeks (with morphine) in aged male rats, and that this effect is likely dependent on the proinflammatory capabilities of morphine via activation of toll-like receptor 4 (TLR4). Here, we extend these findings to show that TLR4 blockade, using the selective TLR4 antagonist lipopolysaccharide from the bacteriumRhodobacter sphaeroides(LPS-RS Ultrapure), ameliorates morphine-induced POCD in aged male rats. Using either a single central preoperative treatment or a 1 week postoperative central treatment regimen, we demonstrate that TLR4 antagonism (1) prevents and reverses the long-term memory impairment associated with surgery and morphine treatment, (2) ameliorates morphine-induced dysregulation of the postsynaptic proteins postsynaptic density 95 and synaptopodin, (3) mitigates reductions in mature BDNF, and (4) prevents decreased activation of the BDNF receptor TrkB (tropomyosin-related kinase B), all at 4 weeks postsurgery. We also reveal that LPS-RS Ultrapure likely exerts its beneficial effects by preventing endogenous danger signal HMGB1 (high-mobility group box 1) from activating TLR4, rather than by blocking continuous activation by morphine or its metabolites. These findings suggest TLR4 as a promising therapeutic target to prevent or treat PNDs.SIGNIFICANCE STATEMENTWith humans living longer than ever, it is crucial that we identify mechanisms that contribute to aging-related vulnerability to cognitive impairment. Here, we show that the innate immune receptor toll-like receptor 4 (TLR4) is a key mediator of cognitive dysfunction in aged rodents following surgery and postoperative morphine treatment. Inhibition of TLR4 both prevented and reversed surgery plus morphine-associated memory impairment, dysregulation of synaptic elements, and reduced BDNF signaling. Together, these findings implicate TLR4 in the development of postoperative cognitive dysfunction, providing mechanistic insight and novel therapeutic targets for the treatment of cognitive impairments following immune challenges such as surgery in older individuals.
Endothelial transmigration hotspots limit vascular leakage through heterogeneous expression of ICAM‐1
Authors: Grönloh Max L B , Arts Janine J G , Palacios Martínez Sebastián , van der Veen Amerens A , Kempers Lanette , van Steen Abraham C I , Roelofs Joris J T H , Nolte Martijn A , Goedhart Joachim , van Buul Jaap D 
Published: November 2022

AbstractUpon inflammation, leukocytes leave the circulation by crossing the endothelial monolayer at specific transmigration “hotspot” regions. Although these regions support leukocyte transmigration, their functionality is not clear. We found that endothelial hotspots function to limit vascular leakage during transmigration events. Using the photoconvertible probe mEos4b, we traced back and identified original endothelial transmigration hotspots. Using this method, we show that the heterogeneous distribution of ICAM‐1 determines the location of the transmigration hotspot. Interestingly, the loss of ICAM‐1 heterogeneity either by CRISPR/Cas9‐induced knockout of ICAM‐1 or equalizing the distribution of ICAM‐1 in all endothelial cells results in the loss of TEM hotspots but not necessarily in reduced TEM events. Functionally, the loss of endothelial hotspots results in increased vascular leakage during TEM. Mechanistically, we demonstrate that the 3 extracellular Ig‐like domains of ICAM‐1 are crucial for hotspot recognition. However, the intracellular tail of ICAM‐1 and the 4th Ig‐like dimerization domain are not involved, indicating that intracellular signaling or ICAM‐1 dimerization is not required for hotspot recognition. Together, we discovered that hotspots function to limit vascular leakage during inflammation‐induced extravasation.
Facet of 4D printing in biomedicine
Authors: Mathur Vidhi , Agarwal Prachi , Srinivasan Varadharajan , Panwar Amit , Vasanthan Kirthanashri S. 
Published: November 2022

AbstractOwing to the success of three-dimensional (3D) printing in biomedical applications, the latest addition to the technology is four-dimensional (4D) printing, which has gained tremendous interest since 2012. 4D printing is being considered as an upgradation and extension of 3D that includes time as a fourth dimension with the utilization of smart biomaterials, and upon the application of any external stimulus, the shape and size of the printed structure change with time. In this review, we highlight the basic techniques involved in 4D printing, the shape memory effect, and various stimuli like light, temperature, pH, etc., that cause the shape change, leading to the transformation of the structures fabricated. 4D printing using smart materials demonstrates shape memory property and their possible applications in the field of biomedicine and regenerative medicine are discussed in detail. The authors have focused on 4D printing of various tissues, with a special highlight on bone and dental tissue.
Graphical abstract
Validation of reinforced concrete bond stress–slip models through an analytical strain distribution comparison
Authors: Dey Alinda , Bado Mattia Francesco , Kaklauskas Gintaris 
Published: November 2022

AbstractThe bond and slip between concrete and the reinforcement bars, cover a key role in the inter-material force transfer of Reinforced Concrete (RC) structures. In light of the lack of tools able to thoroughly inspect the inner workings of RC structures and to extract reliable bond stress values, modern bond stress–slip (Bond–slip) models are often inaccurate and in contradiction with each other. Considering the recent surge of novel hyper-performant strain sampling tools (Distributed Sensing for example), their application for the creation of novel and physically accurate Bond–slip models is just a matter of time. This being said, one of the main reasons behind the modern coexistence of multiple inaccurate and at times contradictory Bond–slip models is the absence of a tool that has allowed researchers to rapidly corroborate and calibrate their newly created models. To this end, the present article proposes such a Bond–slip validation tool for RC elements. This one is designed to extract reinforcement strain profiles at any given load level on the grounds of a specific bond–slip law and geometrical inputs. Said profile is then compared against an experimentally extracted one based on specimens with identical geometrical features. The performance of the validation tool is demonstrated through an application to six existing bond–slip models. Granted the proposal of validation tools is paramount for the future of the discussion on bond–slip modelling, stress-transfer analyses and serviceability of RC structures, the here proposed validation tool is a first significant step in that direction.
EDUCAÇÃO GEOGRÁFICA E PENSAMENTO ESPACIAL: CONCEITOS E REPRESENTAÇÕES
Authors: Castellar Sonia Maria Vanzella , Juliasz Paula Cristiane Strina 
Published: November 2022

O pensamento espacial é um conceito central em nossas pesquisas na Faculdade de Educação da Universidade de São Paulo, pois estão fundamentadas nos conceitos geográficos, nas representações espaciais e nas habilidades do pensamento. Este tipo de pensamento consiste na mobilização do raciocínio sobre o espaço e a representação espacial, promovendo a alfabetização cartográfica e a Educação Geográfica. O objetivo deste artigo é discutir o papel dos mapas mentais no desenvolvimento dos conceitos de cidade, lugar e de paisagem, conceitos estruturantes para Educação Geográfica, tanto para crianças de 5 a 6 anos na Educação Infantil quanto na formação docente, no curso de Pedagogia. O mapa mental foi a representação espacial escolhida como instrumento de pesquisa produzido em Sequências Didáticas. Os mapas mentais apresentam as características fundamentais da localização tais como as condições, como é o lugar e o que existe nele, ou seja, a compreensão das características que pode ser verificada em um lugar, e as conexões, que consiste em compreender como este lugar está ligado aos outros lugares. Em sala de aula, em todos os níveis de ensino, a elaboração e mapas permite o professor compreender o pensamento e espacial que o aluno tem e o que pensa sobre um determinado espaço e tema. Tomamos a cartografia enquanto uma linguagem que permite desenvolver as relações espaciais e temporais e as noções de orientação, distância e localização, construindo os conceitos da ciência geográfica.
“TENDA DOS MILAGRES” DE JORGE AMADO
Authors: E Silva Carmelinda Carla Carvalho , Silva Raimunda Celestina M. da 
Published: November 2022

Os negros africanos e seus descentes mestiços e crioulos deram enormes contribuições para a formação da identidade cultural brasileira. Muitos dos aspectos dessa cultura como a língua, as danças e a religiosidade resistiram ao tempo e as repressões conduzidas pelo colonizador, e hoje fazem parte do cotidiano e da vida de todos os brasileiros. Sua história de sofrimentos e lutas se agrega a própria história do Brasil e servem como norteadoras da identidade nacional. Em Tenda dos Milagres, Jorge Amado aborda as questões do preconceito, do racismo, da intolerância religiosa, da militância contra o preconceito e a violência e o extremismo dos brancos diante dos rituais e cultura de origem africana. Objetivando analisar a obra pelo viés da teoria de resistência utilizou-se como principais aportes teóricos Bosi (2002), Pantoja (2012) Bastide (1971) Mattos (2012) e Sousa (2014) que trata da história e cultura afro-brasileira e ainda Willeman e Lima(2016), que tratam das questões a respeito do preconceito e intolerância religiosa no Brasil.
Colorectal cancer vaccines: in silico identification of tumor-specific antigens associated with frequent HLA-I alleles in the costa rican Central Valley population
Authors: Diego  Morazán-Fernández  , José Arturo  Molina-Mora  
Published: November 2022

Colorectal cancer is a complex disease in which uncontrolled growth of abnormal cells occurs in the large intestine (colon or rectum). The study of tumor-specific antigens (neoantigens), molecules that interact with the immune system, has been extensively explored as a possible therapy called in silico cancer vaccine. Cancer vaccine studies have been triggered by the current high-throughput DNA sequencing technologies. However, there is no universal bioinformatic protocol to study tumor-antigens with DNA sequencing data.
We propose a bioinformatic protocol to detect tumor-specific antigens associated with single nucleotide variants (SNVs) or “mutations” in colorectal cancer and their interaction with frequent HLA alleles (complex that present antigens to immune cells) in the Costa Rican Central Valley population. We used public data of human exome (DNA regions that produce functional products, including proteins). A variant calling analysis was implemented to detect tumorspecific SNVs, in comparison to healthy tissue. We then predicted and analyzed the peptides (protein fragments, the tumor specific antigens) derived from these variants, in the context of its affinity with frequent alleles of HLA type I of the Costa Rican population.
We found 28 non-silent SNVs, present in 26 genes. The protocol yielded 23 strong binders peptides derived from the SNVs for frequent alleles (greater than 8%) for the Costa Rican population at the HLA-A, B and C loci. It is concluded that the standardized protocol was able to identify neoantigens and this can be considered a first step for the eventual design of a colorectal cancer vaccine for Costa Rican patients. To our knowledge, this is the first study of an in silico cancer vaccine using DNA sequencing data in the context of the Costa Rican HLA alleles.