bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficient Metal‐Oriented Electrodeposition of a Co‐Based Metal‐Organic Framework with Superior Capacitive Performance
Authors: Han Yan , Cui Jian , Yu Yue , Chao Yunfeng , Li Dejun , Wang Caiyun , Wallace Gordon G. 
Published: May 2022

AbstractAn efficient cathodic electrodeposition method is developed for coating Co‐based metal‐organic frameworks (Co‐MOF) on carbon fiber cloth (CFC), a widely used substrate in energy fields. The use of a highly active Co metal surface enables nucleation and growth of Co‐MOF in 3D rodlike crystal bundles. When used as a binder‐free electrode (Co‐MOF/CFC) for supercapacitors, it shows a high areal capacitance of 1784 mF cm−2 at 1 mA cm−2, good cycling stability and excellent rate capability. The assembled asymmetric all‐solid‐state supercapacitor device (Co‐MOF/CFC//AC) delivers a high energy density and power density. This work may open up an effective approach to realize the electrosynthesis of MOF films, promoting use in energy storage and conversion fields.
Improved survival of left ventricular assist device carriers in Europe according to implantation eras: results from the PCHF‐VAD registry
Authors: Jakus Nina , Brugts Jasper J. , Claggett Brian , Timmermans Philippe , Pouleur Anne‐Catherine , Rubiś Pawel , Van Craenenbroeck Emeline M. , Gaizauskas Edvinas , Barge‐Caballero Eduardo , Paolillo Stefania , Grundmann Sebastian , D'Amario Domenico , Braun Oscar Ö. , Gkouziouta Aggeliki , Meyns Bart , Droogne Walter , Wierzbicki Karol , Holcman Katarzyna , Planinc Ivo , Skoric Bosko , Flammer Andreas J. , Gasparovic Hrvoje , Biocina Bojan , Lund Lars H. , Milicic Davor , Ruschitzka Frank , Cikes Maja ,   PCHF‐VAD registry
Published: May 2022

AimsTemporal changes in patient selection and major technological developments have occurred in the field of left ventricular assist devices (LVADs), yet analyses depicting this trend are lacking for Europe. We describe the advances of European LVAD programmes from the PCHF‐VAD registry across device implantation eras.Methods and resultsOf 583 patients from 13 European centres in the registry, 556 patients (mean age 53 ± 12 years, 82% male) were eligible for this analysis. Patients were divided into eras (E) by date of LVAD implantation: E1 from December 2006 to December 2012 (6 years), E2 from January 2013 to January 2020 (7 years). Patients implanted more recently were older with more comorbidities, but less acutely ill. Receiving an LVAD in E2 was associated with improved 1‐year survival in adjusted analysis (hazard ratio [HR] 0.58, 95% confidence interval [CI] 0.35–0.98; p = 0.043). LVAD implantation in E2 was associated with a significantly lower chance of heart transplantation (adjusted HR 0.40, 95% CI 0.23–0.67; p = 0.001), and lower risk of LVAD‐related infections (adjusted HR 0.64, 95% CI 0.43–0.95; p = 0.027), both in unadjusted and adjusted analyses. The adjusted risk of haemocompatibility‐related events decreased (HR 0.60, 95% CI 0.39–0.91; p = 0.016), while heart failure‐related events increased in E2 (HR 1.67, 95% CI 1.02–2.75; p = 0.043).ConclusionIn an analysis depicting the evolving landscape of continuous‐flow LVAD carriers in Europe over 13 years, a trend towards better survival was seen in recent years, despite older recipients with more comorbidities, potentially attributable to increasing expertise of LVAD centres, improved patient selection and pump technology. However, a smaller chance of undergoing heart transplantation was noted in the second era, underscoring the relevance of improved outcomes on LVAD support.
Development and Box–Behnken design optimization of a green extraction method natural deep eutectic solvent‐based for phenolic compounds from barley malt rootlets
Authors: Della Posta Susanna , Gallo Valeria , Dugo Laura , De Gara Laura , Fanali Chiara 
Published: May 2022

AbstractIn recent years, attention has been turned finding new sources of phenolic compounds, antioxidant molecules, main by‐products from the agri‐food chain like barley malt rootlets (BMRs). Traditionally, phenolic compounds are extracted from food matrices using different procedures, for example, solid–liquid, liquid–liquid, or solid‐phase extraction techniques employing organic solvents. With the advent of green chemistry, attention has been paid to the search for green, nontoxic, inexpensive, and nonflammable solvents and the natural deep eutectic solvents (NADESs) respect these characteristics. The aim of this project was to develop and optimize an environmentally friendly, inexpensive, and rapid extraction method for phenolic compounds from BMRs using natural DESs as extractive solvents. Several natural DESs were tested as extractive solvents and, among them, the best results in terms of total phenolic content were obtained using a choline chloride‐malic acid (1:2 molar ratio)‐based mixture. Box–Behnken experimental design guaranteed the extraction of 9.51 ± 0.83 gallic acid equivalent/g of BMRs, under the following optimal extraction conditions: 1:21 solid‐to‐liquid ratio, 80°C as extraction temperature, 43 min as the time of extraction, and 29% as a percentage of added water in the NADESs. Phenolic acids and flavonoids were detected in the BMRs extract through HPLC‐PDA/MS analysis.
Effect of steaming on chemical composition of Mediterranean mussel (Mytilus galloprovincialis): Evaluation of potential risk associated with human consumption
Authors: Peycheva Katya , Panayotova Veselina , Stancheva Rositsa , Makedonski Lubomir , Merdzhanova Albena , Cammilleri Gaetano , Ferrantelli Vincenzo , Calabrese Vittorio , Cicero Nicola , Fazio Francesco 
Published: May 2022

AbstractSteaming process is the most popular method for cooking mussels worldwide. The effect of this cooking process on some toxic (Cd, Ni, Pb), essential (Cr, Cu, Fe, Mn, Zn) elements, minerals (Na, K, Ca, Mg), total lipids, and fatty acid profiles in the Mediterranean mussels (Mytilus galloprovincialis) harvested from the Black Sea was studied. Different approaches to assess the benefits and risks (n‐6/n‐3, PUFA/SFA, AI, TI, h/H, EDI, THQ, HI, TR, and HQEFA) were employed. In general, steaming process significantly modified some essential elements and minerals concentrations as well as the fatty acid profiles. Compared to the raw samples, this culinary practice resulted in an increased concentration of Na, Mg, Zn, and saturated fatty acids and a decrease of polyunsaturated fatty acids. Significant changes in the lipid quality indices (PUFA/SFA, AI, TI, and h/H) from the raw samples were observed. No effect on the DHA content was found. However, the significant increase in the absolute content of EPA + DHA indicates that steaming does not compromise the nutritional quality of mussels. Target hazard quotients (THQs) and hazard index (HI) from elemental intake were below 1, indicating that the steamed M. galloprovincialis pose no hazard for the consumers. The target risk (TR) values for Pb, Cr, and Ni were calculated, evaluated, and showed acceptable or negligible levels. In addition, the benefit–risk ratio indicated that the steamed M. galloprovincialis are safe for human consumption.
A theory of change for advising in the 21st century
Authors: Chamberlain Alexa Wesley , Burnside Omari 
Published: May 2022

AbstractAdvising has the potential to serve as a lever for institutional transformation to advance equitable student success. Actualizing the promise of advising requires implementing evidence‐based interventions and giving attention to institutional practices, technology products, policies, and change management strategies that can address key points within a student's higher education journey. This chapter outlines a “theory of change” for why and how building institutional capacities to deliver holistic advising experiences can advance student success efforts, improving outcomes and experiences for Black, Latinx, Indigenous, and poverty affected students.
Transformations in academic advising as a profession
Authors: Troxel Wendy G. , Bridgen Sean , Hutt Chris , Sullivan‐Vance Karen A. 
Published: May 2022

AbstractAs the function of advising has shifted across the higher education landscape, the role of the academic advisor has also evolved. This chapter explores historic and emerging trends in the roles, functions, and professionalization of academic advising, while stressing the need for institutions to situate academic advising within their learning and teaching mission. Drawing from literature surrounding the theories and contexts of academic advising as a profession, as well as research and resources from NACADA: The Global Community for Academic Advising (NACADA), information surrounding the impact and influences of the role of the academic advisor on student success and equity will be addressed alongside the contexts around which the work takes place.
An ecological approach to understanding the scholarship of advising practice and administration
Authors: Young Dallin George , Zeng Wen 
Published: May 2022

AbstractIn order to further the argument for the consideration of advising as a high‐impact practice, there is a need for the organization of knowledge surrounding advising. This chapter contributes to the ongoing efforts to chronicle the landscape of literature on the scholarship, administration, and practice of advising. Summarization of the major themes found in empirical and best practices literature, as well as a synthesis of learning from advising‐related reports is provided alongside the introduction of a typology that draws from Bronfenbrenner's Ecological Model in an effort to organize research approaches to advising in the field of higher education.
Being HIP: Advising as an emerging high‐impact practice
Authors: Keup Jennifer R. , Young Dallin George 
Published: May 2022

AbstractHistorically, High Impact Practices (HIPs) have been identified as experiential learning initiatives that were proven to be effective for engagement and student success, are characterized by eight tenets of practice, and contribute to student learning, development, and achievement. Yet, national research and institutional assessment data indicate that many other curricular and cocurricular practices are educationally purposeful, effective, and maintain fidelity to the eight elements of HIPs. Drawing from existing research and national data, including information collected by the National Resource Center for The First‐Year Experience and Students in Transition, this chapter will analyze advising practices against the eight tenets of AAC&U's high‐impact practices to make the case for its position as an emergent HIP.
Exploration of high dimensional free energy landscapes by a combination of temperature‐accelerated sliced sampling and parallel biasing
Authors: Gupta Abhinav , Verma Shivani , Javed Ramsha , Sudhakar Suraj , Srivastava Saurabh , Nair Nisanth N. 
Published: May 2022

AbstractTemperature‐accelerated sliced sampling (TASS) is an enhanced sampling method for achieving accelerated and controlled exploration of high‐dimensional free energy landscapes in molecular dynamics simulations. With the aid of umbrella bias potentials, the TASS method realizes a controlled exploration and divide‐and‐conquer strategy for computing high‐dimensional free energy surfaces. In TASS, diffusion of the system in the collective variable (CV) space is enhanced with the help of metadynamics bias and elevated‐temperature of the auxiliary degrees of freedom (DOF) that are coupled to the CVs. Usually, a low‐dimensional metadynamics bias is applied in TASS. In order to further improve the performance of TASS, we propose here to use a highdimensional metadynamics bias, in the same form as in a parallel bias metadynamics scheme. Here, a modified reweighting scheme, in combination with artificial neural network is used for computing unbiased probability distribution of CVs and projections of high‐dimensional free energy surfaces. We first validate the accuracy and efficiency of our method in computing the four‐dimensional free energy landscape for alanine tripeptide in vacuo. Subsequently, we employ the approach to calculate the eight‐dimensional free energy landscape of alanine pentapeptide in vacuo. Finally, the method is applied to a more realistic problem wherein we compute the broad four‐dimensional free energy surface corresponding to the deacylation of a drug molecule which is covalently complexed with a β‐lactamase enzyme. We demonstrate that using parallel bias in TASS improves the efficiency of exploration of high‐dimensional free energy landscapes.
Absorption thermodynamic and kinetics of heavy metals by magnetic hydrogel nanocomposite absorbents with semi‐interpenetrating networks structure
Authors: Wan Tao , Wang Tairan , Wang Jian , He Songsong , Tang Qi , Yu Mingrui , Jia Yang 
Published: May 2022

AbstractKH570‐modified magnetic hydrogel nanocomposite absorbents (KH570‐mHNAs) with semi‐interpenetrating networks (semi‐IPNs) were synthesized by radical copolymerization based on poly(acrylamide‐co‐acrylic acid), PVP and KH570‐modified magnetic nanoparticles. KH570‐mHNAs with porous and ravine structure have the target structure confirmed by FTIR and XRD results. KH570‐mHNAs have high adsorption capacities of Cu(II) (163 mg/g), Cd(II) (150 mg/g), and Pb(II) (460.8 mg/g), approaching the absorption equilibrium at 60 min. Heavy metal absorption was highly dependent on different process variables, such as pH value, initial heavy metal ion concentration, contact time, and temperature. The endothermic, entropy increasing, and spontaneous nature of heavy metal ion adsorption was revealed from thermodynamic study. Heavy metal ions adsorption isotherms and kinetics were in agreement with the Langmuir model and pseudo‐second‐order kinetic model, respectively. Besides, KH570‐mHNAs had good magnetic responsiveness, desorption, and reusability, which made it a promising adsorbent for removing heavy metal ions from the contaminated wastewater.
Biocontrol Aspergillus species together with plant biomass alter histochemical characteristics in diseased mungbean plants
Authors: Khan Iqra Haider , Javaid Arshad 
Published: May 2022

AbstractIn the present study, two Aspergillus species as biocontrol agents together with Chenopodium quinoa dry biomass were used to investigate their effects on histochemical features of mungbean plant inoculated with M. phaseolina. In a pot experiment, Aspergillus flavipes and Aspergillus versicolor were added either alone or together with 1%, 2%, and 3% dry biomass of quinoa (DBQ) to the pot soil already inoculated with M. phaseolina. After 4 weeks of sowing, root and lower‐stem sections of the mungbean plants were stained with ferric chloride, phloroglucinol‐HCl and Lugol's iodine to detect the presence of polyphenols, lignin, and starch granules, respectively, and observed under light microscope. Stem and root sections were also observed under scanning electron microscope (SEM) to reveal the effect of soil amendments on cell structures. The findings revealed that mungbean plant cross sections from all the treatments except positive control (only inoculated with M. phaseolina) showed very clear cell structures. In positive control, distorted, fragmented, and collapsed cell structures were observed. Moreover, M. phaseolina blocked vascular vessels in comparison to negative control where the cell structures were intact and normal in size. Plant sections from treatments with A. flavipes and A. versicolor alone or together with DBQ were without pathogen colonization, with normal cell structures and a high deposition of gel. The results suggested that the two Aspergillus spp. and C. quinoa induced defense responses in mungbean plants.Highlights
Macrophomina phaseolina causes significant yield losses in mungbean.
Pot soil was amended with two species of Aspergillus as biocontrol agents along with plant biomass.
Aspergillus spp. markedly saved the root and stem structures from the damage caused by M. phaseolina.
Severe aplastic anaemia after serial vaccinations for SARS‐CoV‐2, pneumococcus and seasonal influenza
Authors: Wang Xiao , Laczko Dorottya , Caponetti Gabriel C. , Rabatin Susan , Babushok Daria V. 
Published: May 2022

AbstractWe present a 67‐year‐old woman who developed progressive pancytopenia over 10 months, concomitant with administration of severe adult respiratory syndrome coronavirus‐2 (SARS‐CoV‐2), pneumococcal and influenza vaccines. She developed mild leukopenia ∼2 weeks after the SARS‐CoV‐2 mRNA vaccine sequence, with progressive symptoms after subsequent vaccines, eventually developing severe aplastic anaemia (SAA). While there have been several reports of vaccine‐related SAA, at time of submission, our case is the first reported to develop after the Moderna mRNA SARS‐CoV‐2 vaccine, as well as the first to document the gradual development of SAA over the course of many vaccine exposures. Physicians should be cognizant of vaccine‐associated SAA, considering current widespread coronavirus disease 2019 vaccination efforts.
Top‐down and bottom‐up: Examining reciprocal relationships between leader humility and team helping behavior
Authors: Wang Danni , Liu Yuwen , Hsieh Ying‐Che , Zhang Zhen 
Published: May 2022

SummaryBased on social exchange theory, we develop and test a longitudinal model in which leaders' expressed humility and team members' helping behavior reciprocally influence each other over time and ultimately predict subsequent team performance and turnover. Using multisource, 3‐wave repeated measures data from 281 work teams, our cross‐lagged panel modeling results supported the hypotheses. We found that leader humility increased subsequent team helping behavior, and team helping behavior also promoted leader humility at a later time. As compared with leader humility, team helping behavior is a more proximal predictor of team performance and reduced team turnover rate. We found that leader humility has indirect effects on team performance and team turnover through the mediating role of team helping behavior. These findings shed new light on how leaders and teams can develop through their respective humble and helping behaviors, and how this reciprocal relationship ultimately enhances team effectiveness and helps reduce turnover of team members.
Management of short‐bowel syndrome: A survey of unmet educational needs among healthcare providers
Authors: Belcher Emily , Mercer David , Raphael Bram P. , Salinas Gregory D. , Stacy Sylvie , Tappenden Kelly A. 
Published: May 2022

AbstractBackgroundManagement of short‐bowel syndrome with intestinal failure (SBS‐IF) is complex and requires a multidisciplinary approach. Because of the rarity of SBS‐IF, healthcare professionals (HCPs) often lack clinical experience with the disease and may benefit from education regarding SBS‐IF and its management. This study identified unmet educational needs related to the management of patients with SBS‐IF.MethodsThis was a prospective, web‐based survey (December 2019–January 2020) in which a series of clinical questions were posed to US HCPs after presenting three standardized SBS‐IF cases to assess current practice patterns. HCPs were then asked a series of questions to identify potential knowledge gaps and unmet educational needs relating to SBS‐IF management.ResultsOverall, 558 HCPs completed the survey, with 12%–38% having a formal SBS‐IF multidisciplinary team currently available to make treatment decisions within their institution. Clinicians involved in care included gastroenterologists (93%), registered dietitians (79%), gastroenterology nurse practitioners and physician assistants (37%), registered nurses (43%), social workers (45%), and psychologists/psychiatrists (27%). There was underuse of published guidelines and limited understanding of the course of intestinal adaptation. Responses to the clinical scenarios highlighted disparities in SBS‐IF care delivery, including diagnosis, management goals, medications prescribed, and nutrition practices.ConclusionsFuture SBS‐IF educational interventions for HCPs should aim to improve awareness and understanding of the disease, facilitate timely diagnosis, and standardize management practices to ensure patients receive optimal interdisciplinary care as widely as possible.
Effects of glepaglutide, a long‐acting glucagon‐like peptide‐2 analog, on intestinal morphology and perfusion in patients with short bowel syndrome: Findings from a randomized phase 2 trial
Authors: Naimi Rahim M. , Hvistendahl Mark K. , Poulsen Steen S. , Kissow Hannelouise , Pedersen Jens , Nerup Nikolaj A. , Ambrus Rikard , Achiam Michael P. , Svendsen Lars B. , Jeppesen Palle B. 
Published: May 2022

AbstractBackgroundThe proadaptive effects of glucagon‐like peptide‐2 (GLP‐2) include stimulation of intestinal mucosal growth as well as intestinal blood flow and angiogenesis. We have recently reported that daily subcutaneous injections of glepaglutide, a long‐acting GLP‐2 analog, improved intestinal absorptive function in patients with short bowel syndrome (SBS). As secondary and exploratory end points, the effects of glepaglutide on intestinal morphology and perfusion are reported.MethodsThe following assessments were done in 18 patients with SBS in a randomized, crossover, dose‐finding, phase 2 trial before and after three weeks of treatment with glepaglutide: plasma citrulline and mucosa biopsies to assess changes in (1) intestinal morphology by immunohistochemistry and (2) gene expressions associated with absorption, proliferation, and markers of tight‐junction integrity by quantitative polymerase chain reaction. Intestinal perfusion was assessed in stoma nipples by laser speckle contrast imaging and quantitative fluorescence angiography with indocyanine green.ResultsIn the 1‐ and 10‐mg dose groups, glepaglutide significantly increased plasma citrulline by 15.3 µmol/L (P = 0.001) and 15.6 µmol/L (P = 0.001), respectively. Trends toward an increase in villus height, crypt depth, and epithelium height were seen in the same groups. No significant changes were seen in gene expressions or intestinal perfusion.ConclusionThe increase in plasma citrulline and the morphological improvements may partly account for improvement in the intestinal absorptive function. However, the finding of a stability in perfusion after three weeks of treatment with glepaglutide may have been preceded by a more profound acute‐phase increase in intestinal perfusion at treatment initiation.