bluuebunny/crossref_metadata_2025_split huggingface dataset:
Household Welfare, Extreme and Chronic Poverty Between Indigenous Groups of Bolivia
Authors: Castellanos Iván Velásquez , Rahut Dil Bahadur 
Published: September 2022

AbstractAbstractThis study examines the determinants of household welfare, extreme and chronic poverty among indigenous peoples among three different ethnic groups: Aymaras, Quechuas and Chipayas in rural Bolivia using primary panel data set collected in 2004 and 2005 from rural areas of La Paz, Oruro, Potosi and Chuquisaca departments. It was found that ethnicity and indigenous origins are closely associated with extreme and chronic poverty among rural communities. The OLS and the logit estimations shows that the household size and composition, education, literacy, livestock assets, migration, access to the market are important determinants of welfare and chronic poverty. It was also found that the households from Oruro, Chuquisaca and Potosi departments have higher probability of becoming chronic poor compared to households from the La Paz Department, which indicates the disparity in the regional development.
DOD and NGOs in Haiti ‐ A Successful Partnership
Authors: James Terbush , Cubano Miguel 
Published: September 2022

AbstractThe 2010 Haiti Earthquake was the deadliest single disaster in this Hemisphere, ever. International Aid Organizations and Governments rushed to assist the survivors. Among these, the US Department of Defense played a significant role. Alongside DoD however were a large number of NGO volunteers onboard the USNS Comfort hospital ship, which provided critical specialty skills. This partnership, DoD and NGOs, has already demonstrated significant benefit in lives saved and suffering mitigated. Various lessons learned are noted and recommendations for improvement in the way NGOs are sourced and integrated for these missions. However, the greatest benefit could be in future disaster response when synergies developed from combined training and exercises allow DoD and NGOs to respond seamlessly and effectively to another major disaster, together.
Understanding the Role of Policy Narratives and the Public Policy Arena: Obesity as a Lesson in Public Policy Development
Authors: Clemons Randy S. , McBeth Mark K. , Kusko Elizabeth 
Published: September 2022

AbstractAs witnessed by recent national policy battles over health care and climate change, the policy environment in the United States (U.S.) is increasingly politically polarized. U.S. public policy is progressively driven by divisive symbols and dominated by morality debates often articulated in the form of emotional narratives. One such issue that has gained attention in the U.S., partially due to efforts of First Lady Michelle Obama, is the increasing levels of obesity. Obesity policy advocates warn that the U.S. is facing a crisis that impacts not only our health, but our national competitiveness; not only our military preparedness, but our national security. Our goal is not to get involved in the scientific debate over obesity and its costs to society but rather to explore the role that policy narratives and causal attribution play in determining attitudes toward obesity and obesity policy. We contend that an individual's view of obesity is shaped by their view of individual rights and responsibilities and of individual morality; and determined more by stories (especially narratives that “fit” with those views) than by science. Our paper seeks to test whether science or other factors primarily shape one's view of government's appropriate role relative to the obesity issue and to examine which of two foundational moral narratives is more convincing in the obesity policy realm. Using a sample of 172 respondents at two institutions of higher education in the United States, we find that a “Strict Father Morality” narrative was more convincing than a science statement in influencing an individual's view of obesity. Respondents believed that obesity was a serious problem, but they were deeply divided over government's role in addressing the obesity issue. Female respondents were the most supportive of governmental efforts to address obesity. We explore the potential impact of our findings for public policy development and future research.
Measles, Mumps, and Rubella Vaccines and Diagnoses of Autism Spectrum Disorders among Children: A Meta‐Analysis
Authors: Hobson Kristin A. , Mateu Pedro F. , Coryn Chris L. S. , Graves Charlene 
Published: September 2022

AbstractPurpose: The authors of the study sought, through a meta‐analysis of primary studies, to same for those who receive a measles, mumps, and rubella (MMR) vaccination and those who do not?” Background: Despite evidence from numerous sources failing to demonstrate consistent evidence of ASD diagnoses as a consequence of receiving MMR vaccinations, parents/guardians sometimes forego vaccinating their children. Methods: Three researchers searched for and obtained relevant studies, and two researchers independently applied a standardized data extraction form to the included studies. Results: Seven independent effect sizes were calculated, yielding a pooled random‐effects OR* = 0.25 (95% CI, LL = 0.09, UL = 0.76) (*denotes random‐effects estimate). Under the fixedeffect model, the OR = 0.33 (95% CI, LL = 0.25, UL = 0.45). Conclusions: The odds of ASD diagnoses attributable to receiving or not receiving an MMR vaccination are not indistinguishable within clinical limits of indifference. Even so, the odds of ASD diagnoses are substantially smaller for those receiving an MMR vaccination than for those who do not.
Housing Taxation and Economic Growth: Analysis of a Balanced-Growth Model with Residential Capital
Authors: Vinson Philip 
Published: September 2022

Abstract
Using a neoclassical model with endogenous growth, this study examines the effects of increasing housing taxation and eliminating the mortgage interest tax deduction on economic growth and household welfare in the United States. The optimal tax policy reduces taxation of income in favor of increased taxation of housing and consumption. This policy increases the growth rate by 0.49 percentage points. In addition, simply shifting the tax burden by reducing the tax rates on productive forms of capital toward housing can increase the growth rate up to 0.18 percentage points. This study also find that eliminating the income tax deduction on mortgage interest and lowering income taxes would increase growth by about 0.016 percentage points. Each of these proposed policies improves household welfare.
Energetics of carboxylic acid–pyridine heterosynthon revisited: A computational study of intermolecular hydrogen bond domination on phenylacetic acid–nicotinamide cocrystals
Authors: Kusuma Aris Perdana , Soewandhi Sundani Nurono , Mauludin Rachmat , Suendo Veinardi , Kurniawan Fransiska , Pamungkas Gawang , Nugraha Yuda Prasetya 
Published: September 2022

Abstract
Carboxylic acid–pyridine heterosynthon (CPHS) is one of the most common synthons found in cocrystal packing. Phenylacetic acid (PYC)–nicotinamide (NIC) (PYCNIC) cocrystals were used as a computational model to assess the most important factor in the emergence of the synthon. Geometry optimization was carried out on every possible two molecules of PYC–NIC conformation based on B3LYP-D3BJ/6-311G (d,p). Various energetic parameters, including total energy, interaction energy, and hydrogen bond energy, were used to compare the existing conformation to the putative conformation. The conformation with CPHS has −53.87 kJ mol−1 of single intermolecular hydrogen bond energy (EHB), which is the strongest of all. It turns out that there is no other parameter better than EHB to describe the superiority of CPHS in PYCNIC.
Coherent categorification of quantum loop algebras: The SL(2) case
Authors: Shan Peng , Varagnolo Michela , Vasserot Eric 
Published: September 2022

AbstractWe construct an equivalence of graded Abelian categories from a category of representations of the quiver-Hecke algebra of typeA1(1){A_{1}^{(1)}}to the category of equivariant perverse coherent sheaves on the nilpotent cone of typeA. We prove that this equivalence is weakly monoidal. This gives a representation-theoretic categorification of the preprojective K-theoretic Hall algebra considered by Schiffmann and Vasserot. Using this categorification, we compare the monoidal categorification of the quantum open unipotent cells of typeA1(1){A_{1}^{(1)}}given by Kang, Kashiwara, Kim, Oh and Park in terms of quiver-Hecke algebras with the one given by Cautis and Williams in terms of equivariant perverse coherent sheaves on the affine Grassmannians.
A note on the convergence of Phillips operators by the sequence of functions via q-calculus
Authors: Kiliçman Adem , Ayman-Mursaleen Mohammad , Nasiruzzaman Md. 
Published: September 2022

Abstract
The basic aim of this study is to include nonnegative real parameters to allow for approximation findings of the Stancu variant of Phillips operators. We concentrate on the uniform modulus of smoothness in a simple manner before moving on to the approximation in weighted Korovkin’s space. Our study’s goals and outcomes are to fully develop the uniformly approximated findings of Phillips operators. We determine the order of convergence in terms of Lipschitz maximal function and Peetre’s K-functional. In addition, the Voronovskaja-type theorem is also proved.
Application of vibrational spectroscopy and nuclear magnetic resonance methods for drugs pharmacokinetics research
Authors: Rafalskiy Vladimir V. , Zyubin Andrey Yu. , Moiseeva Ekaterina M. , Kupriyanova Galina S. , Mershiev Ivan G. , Kryukova Nadezhda O. , Kon Igor I. , Samusev Ilya G. , Belousova Yana D. , Doktorova Svetlana A. 
Published: September 2022

Abstract

Objectives
The development of new methods for determining the concentration of drugs is an actual topic today. The article contains a detailed review on vibrational spectroscopy and nuclear magnetic resonance methods using for pharmacokinetic research. This study is devoted to the possibility of using vibrational spectroscopy and 1H nuclear magnetic resonance spectroscopy to determine the concentration of drugs and the use of these groups of techniques for therapeutic drug monitoring.

Content
The study was conducted by using scientific libraries (Scopus, Web of Science Core Collection, Medline, GoogleScholar, eLIBRARY, PubMed) and reference literature. A search was conducted for the period from 2011 to 2021 in Russian and English, by combinations of words: 1H nuclear magnetic resonance (1H NMR), vibrational spectroscopy, Surface-Enhanced Raman spectroscopy, drug concentration, therapeutic drug monitoring. These methods have a number of advantages and are devoid of some of the disadvantages of classical therapeutic drug monitoring (TDM) methods – high performance liquid chromatography and mass spectrometry. This review considers the possibility of using the methods of surface-enhanced Raman scattering (SERS) and 1H NMR-spectroscopy to assess the concentration of drugs in various biological media (blood, urine), as well as to study intracellular metabolism and the metabolism of ophthalmic drugs. 1Н NMR-spectroscopy can be chosen as a TDM method, since it allows analyzing the structure and identifying metabolites of various drugs. 1Н NMR-based metabolomics can provide information on the side effects of drugs, predict response to treatment, and provide key information on the mechanisms of action of known and new drug compounds.

Summary and outlook
SERS and 1Н NMR-spectroscopy have great potential for further study and the possibility of introducing them into clinical practice, including for evaluating the efficacy and safety of drugs.
SLCO1B1 c.521T>C gene polymorphism decreases hypoglycemia risk in sulfonylurea-treated type 2 diabetic patients
Authors: Ragia Georgia , Atzemian Natalia , Maslarinou Anthi , Manolopoulos Vangelis G. 
Published: September 2022

Abstract

Objectives
Pharmacogenomics can explain some of the heterogeneity of sulfonylurea (SU)-related hypoglycemia risk. Recently, a role of OATP1B1, encoded by SLCO1B1 gene, on SU liver transport prior of metabolism has been uncovered. The aim of the present study was to explore the potential association of SLCO1B1 c.521T>C polymorphism, leading to reduced OATP1B1 function, with SU-related hypoglycemia risk.

Methods
Study cohort consists of 176 type 2 diabetes patients treated with the SUs glimepiride or gliclazide. 92 patients reported SU-related hypoglycemia, while 84 patients had never experienced a hypoglycemic event. Patients were previously genotyped for CYP2C9 *2 and *3 variant alleles that lead to decreased enzyme activity of the SU metabolizing enzyme CYP2C9 and have been associated with increased SU-related hypoglycemia risk. SLCO1B1 c.521T>C polymorphism was genotyped by use of PCR-RFLP analysis.

Results

SLCO1B1 c.521TC genotype frequency was significantly lower in hypoglycemic cases than non-hypoglycemic controls (15.2% vs. 32.1%, p=0.008). In an adjusted model, c.521TC genotype significantly reduced the risk of hypoglycemia (OR 0.371; 95% C.I. 0.167–0.822; p=0.015). In CYP2C9 intermediate metabolizers (n=54) c.521TC genotype frequency was significantly decreased in cases compared to controls (3 out of 36 cases, 8.3% vs. 7 out of 18 controls, 38.9%, p=0.012). A similar albeit not significant difference of SLCO1B1 c.521TC genotype was present in CYP2C9 extensive metabolizers (n=120) (18.2% in cases vs. 30.8% in controls, p=0.113).

Conclusions
We have found a protective effect of SLCO1B1 c.521C variant on SU-related hypoglycemia risk both independently and in interaction with CYP2C9 phenotypes. Our results suggest a possible linkage of SLCO1B1 c.521T>C polymorphism with variants in other genes impairing OATPs expressed in pancreatic islets that could interfere with SU tissue distribution.
The affective allure – a phenomenological dialogue with David Miall’s studies of foregrounding and feeling
Authors: Sopcak Paul , Kuiken Don 
Published: September 2022

Abstract
This paper attempts to rescue the notion of foregrounding from the prevailing focus on defamiliarization. It does so by engaging in a phenomenological dialogue with David Miall’s account of foregrounding and feeling and Viktor Shklovsky’s discussion of literary device and aesthetic function. In particular, it contextualizes Miall’s proposal of the response to foregrounding as a feeling-guided process involving boundary crossings, a defamiliarization-refamiliarization cycle, and self-transformative feelings within Husserl’s philosophical analysis of sense constitution. Miall’s feeling explorations and explications find their counterpart in Husserl’s active egoic turning toward the affective allure and enticement of affective resonances. Using Miall’s work as a touchstone, some frequently overlooked aspects of Shklovsky’s conception of ostranenie are clarified by drawing on Husserl’s notions of the natural attitude, active and passive synthesis, affective allure, expressive explication, and awakenings.
Use of letrozole to augment height outcome in pubertal boys: a retrospective chart review
Authors: Likki Snigdha R. , Allen Holley F. , Knee Alexander , Tonyushkina Ksenia N. 
Published: September 2022

Abstract

Objectives
We describe growth patterns and predicted adult height (PAH) in pubertal boys treated with letrozole and evaluate the potential predictors of growth responses.

Methods
We performed a retrospective analysis of data from 2002 to 2020. All subjects were treated for ≥6 months and had at least 3 height measurements to calculate the growth velocity (GV) before and during treatment. We evaluated growth measurements, bone age, and biochemical parameters before, during and after treatment.

Results
A total of 59 subjects aged 12.7 (± 1.7) years old were included. At treatment initiation, bone age was 13.1 (± 1.5) years and predicted adult height (PAH) was 163.8 (± 9.9) cm compared to mid-parental height of 172.4 (± 5.8) cm. Growth velocity decreased during letrozole therapy and rebounded after completion. Sub-analysis of 26 subjects with bone age data available at baseline and at least 1 year later showed a trend to modest increase in PAH. In boys simultaneously receiving growth hormone (rhGH), the change in PAH was significantly more (3.2 cm, p<0.05) compared to those treated with letrozole alone.

Conclusions
We show that letrozole appropriately slows down skeletal maturation and GV responses are variable. Possible negative predictors include lower baseline GV and advanced bone age. A small positive trend in PAH with letrozole therapy is augmented by simultaneous use of rhGH. Future randomized controlled trials are needed to better understand which group of patients will benefit from treatment.
Utility of head CT scan in treatment decisions for suspected cerebral edema in children with DKA
Authors: Wilkinson Kristy , Sanghamitra Sinha , Nair Priya , Sanchez Javier , Ambati Shashikanth 
Published: September 2022

Abstract

Objectives
Cerebral edema (CE) remains one of the most feared complications of diabetic ketoacidosis (DKA) with severe morbidity and mortality. The use of computerized tomography (CT) scan in the setting of suspected cerebral edema in DKA has been minimally studied. The objective of our study was to evaluate the utility of CT scans in children with suspected cerebral edema, and secondarily to analyze the various patient characteristics of those with and without cerebral edema.

Methods
We performed a retrospective chart review of all the children with DKA secondary to T1DM admitted to our tertiary PICU in order to obtain demographic data, laboratory results, and their treatment course. Differences between the groups of suspected CE and no suspected CE were compared using linear and logistic regression for continuous and binary variables respectively.

Results
We identified 251 patients with DKA, 12 of which had suspected CE; 67% (8/12) of those patients received head CT and 87.5% (7/8) of them were read as normal. On the other hand, 33% (4/12) did not receive CT scan of head, and yet three of the four patients were treated for CE.

Conclusions
In our cohort of patients, CT results did not influence CE treatment or lack thereof; most patients with suspected CE were treated with or without head CT findings of CE, indicating that imaging has very little utility in our cohort of patients. In some cases, the use of head CT delayed the onset of treatment for CE.
Re-constructing Kant: Kant’s Teleological Moral Realism
Authors: Rodriguez Facundo 
Published: September 2022

AbstractIt is common for constructivists to claim that Kant was the first philosopher to understand moral facts as ‘constructions of reason’. They think that Kant, just like the constructivist, proposes a procedure – the Categorical Imperative – from which the order of value can be ‘constructed’ and grounds the validity of this construction procedure not in some previous value but in its capacity to solve a practical problem, the problem of ‘free agency’. I here argue that this reading is misguided and propose that we read Kant as a teleological realist instead. Kant is a realist in that he takes the value of rational nature to be objective and so not ‘constructed’. Kant is a teleological realist insofar as his derivation of the moral law from the objective value of rational nature relies on a teleological understanding of rational nature.
Kantian Constructivism and the Sources of Normativity
Authors: Schaab Janis David 
Published: September 2022

AbstractWhile it is uncontroversial that Kantian constructivism has implications for normative ethics, its status as ametaethicalview has been contested. In this article, I provide a characterisation of metaethical Kantian constructivism that withstands these criticisms. I start by offering a partial defence of Sharon Street’spractical standpoint characterisation.However, I argue that this characterisation, as presented by Street, is ultimately incomplete because it fails to demonstrate that the claims of Kantian constructivism constitute a distinctive contribution to metaethics. I then try to complete the practical standpoint characterisation by elaborating on Christine Korsgaard’s suggestion that metaethical Kantian constructivism takes up a position on thesourceof morality’s normativity.
Noninvasive diagnosis of AIH/PBC overlap syndrome based on prediction models
Authors: Wang Kailing , Li Yong , Pan Jianfeng , He Huifang , Zhao Ziyi , Guo Yiming , Zhang Xiaomei 
Published: September 2022

Abstract
Autoimmune liver diseases (AILDs) are life-threatening chronic liver diseases, mainly including autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and AIH–PBC overlap syndrome (OS), which are difficult to distinguish clinically at early stages. This study aimed to establish model to achieve the purpose of the diagnosis of AIH/PBC OS in a noninvasive way. A total of 201 AILDs patients were included in this retrospective study who underwent liver biopsy during January 2011 to December 2020. Serological factors significantly associated with OS were determined by the univariate analysis. Two multivariate models based on these factors were constructed to predict the diagnosis of AIH/PBC OS using logistic regression and random forest analysis. The results showed that immunoglobulins G and M had significant importance in both models. In logistic regression model, anti-Sp100, anti-Ro-52, anti-SSA, or antinuclear antibody positivity were risk factors for OS. In random forest model, activated partial thromboplastin time and ɑ-fetoprotein level were important. To distinguish PBC and OS, the sensitivity and specificity of logistic regression model were 0.889 and 0.727, respectively, and the sensitivity and specificity of random forest model were 0.944 and 0.818, respectively. In conclusion, we established two predictive models for the diagnosis of AIH/PBC OS in a noninvasive method and they showed better performance than Paris criteria for the definition of AIH/PBC OS.
Numerical simulation of heat pump drying system for paper exhaust hood
Authors: Yan Yan , Li Wen 
Published: September 2022

Abstract
In view of the present situation that the exhaust waste heat of the hot air hood in the paper drying section is too much and the environment is not friendly, a closed heat pump drying system model applied to the exhaust air hood is proposed and established. Effects of evaporation temperature and condensation temperature on supply air temperature, supply air moisture content, system performance coefficient (COP) and dehumidification energy consumption ratio (SMER) were studied. Results show that with the increase of condensation temperature, the supply air temperature is unchanged, and the moisture content of the supply air increase, while the COP and SMER of the system show a downward trend. The moisture content of supply air decrease with the increase of evaporation temperature, while the supply air temperature, COP and SMER all show an upward trend. Therefore, in order to improve the drying characteristics and improve the performance of the heat pump system, the condensation temperature can be reduced and the evaporation temperature can be increased.
Categorizing threat types and cyber-assaults over Internet of Things-equipped gadgets
Authors: Sharma Abhinav , Gupta Anand Kumar , Shabaz Mohammad 
Published: September 2022

AbstractInternet of Things (IoT) gadgets are very attractive globally, and IoT facilities are universal. Their progress has not been ignored, and the number of invaders and outbreaks on IoT and facilities is growing. Because cyber-assaults are zero-trust to the IoT, and the IoT is deeply ingrained in our lives and culture, we must embrace a comprehensive Zero-Trust strategy for cyber defense. As a result, the new model is no longer vulnerable to fear and outbreak on the IoT structure. In this article, an effort is made to categorize threat types and analyze and explain invaders and assaults on IoT gadgets and facilities.