bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of topography, climate, soil and the surrounding matrix in the distribution of Veredas wetlands in central Brazil
Authors: Gonçalves Rogério Victor S. , Cardoso João Custódio F. , Oliveira Paulo Eugênio , Raymundo Diego , de Oliveira Denis Coelho 
Published: September 2022

AbstractWetlands are among the most important ecosystems in the world in terms of endemic biodiversity, carbon storage and hydrological process. Veredas wetlands are distributed across the Brazilian savanna (i.e. Cerrado biome) and are permanently protected areas. Veredas wetlands have a hydromorphic soil, providing water to the main rivers of central Brazil and allowing the occurrence of several endemic species of plants and animals. Although recent studies on biotic and abiotic characteristics have been conducted in several areas of Veredas, the studies are local and there is a lack of information about large-scale patterns. Here we used remote sensing data to explore the role of climate, soil, topography and surrounding matrix explaining Veredas occurrence in the Triângulo Mineiro and Alto Paranaíba (TMAP), a mesoregion of the State of Minas Gerais, Southeastern Brazil. Veredas were more frequent in the western region of TMAP, in areas with lower altitudes, temperature and precipitation seasonality, soil cation exchange capacity, silt and sand content, and slope. Moreover, farming was the most frequent land use in areas surrounding Veredas. Veredas are associated with recharging of the water table and water flow that maintains rivers in the Upper Paraná River water basin. We trust the present assessment will be of help for the development of conservation strategies and biodiversity studies.
Graphical abstract

Research questions, data processing, statistical analysis and illustration of the outputs generated.
Submerged membrane/adsorption hybrid process in water reclamation and concentrate management—a mini review
Authors: Loganathan Paripurnanda , Kandasamy Jaya , Ratnaweera Harsha , Vigneswaran Saravanamuthu 
Published: September 2022

AbstractClean water shortage is a major global problem due to escalating demand resulting from increasing human population growth and industrial activities, decreasing freshwater resources and persistent droughts. Recycling and reuse of wastewater by adopting efficient reclamation techniques can help solve this problem. However, wastewater contains a wide range of pollutants, which require removal before it may be reused. Adsorption and membrane processes are two successful treatments used to remove most of these pollutants. Their efficiency increases when these processes are integrated as observed, for example in a submerged membrane adsorption hybrid system (SMAHS). It uses coarse air bubbling/sparging to produce local shear which minimises reversible membrane fouling, improves performance and extends the life of the membrane. Additionally, the adsorbent acts as a buoyant media that produces an extra shearing effect on the membrane surface, reduces membrane resistance and increases flux. In addition, it adsorbs the organics that would otherwise deposit on and cause fouling of the membrane. The use of activated carbon (AC) adsorbent in SMAHS is very effective in removing most pollutants including natural organic matter (NOM) and organic micropollutants (OMPs) from wastewaters and membrane concentrate wastes, the latter being a serious problem in practical applications of the reverse osmosis process. However, certain NOM fractions and OMPs (i.e. hydrophilic and negatively charged ones) are not efficiently removed by AC. Other adsorbents need to be explored for their effective removal.
Graphical abstract
PITPNC1 promotes the thermogenesis of brown adipose tissue under acute cold exposure
Authors: Tang Guoqing , Ma Chengxin , Li Liangkui , Zhang Shaoyan , Li Fengsheng , Wu Jin , Yin Yesheng , Zhu Qing , Liang Yan , Wang Ru , Huang He , Zhao Tong-Jin , Yang Hongyuan , Li Peng , Chen Feng-Jung 
Published: September 2022

AbstractBrown adipose tissue (BAT) plays an essential role in non-shivering thermogenesis. The phosphatidylinositol transfer protein, cytoplasmic 1 (PITPNC1) is identified as a lipid transporter that reciprocally transfers phospholipids between intracellular membrane structures. However, the physiological significance of PITPNC1 and its regulatory mechanism remain unclear. Here, we demonstrate that PITPNC1 is a key player in thermogenesis of BAT. While Pitpnc1−/− mice do not differ with wildtype mice in body weight and insulin sensitivity on either chow or high-fat diet, they develop hypothermia when subjected to acute cold exposure at 4°C. The Pitpnc1−/− brown adipocytes exhibit defective β-oxidation and abnormal thermogenesis-related metabolism pathways in mitochondria. The deficiency of lipid mobilization in Pitpnc1−/− brown adipocytes might be the result of excessive accumulation of phosphatidylcholine and a reduction of phosphatidic acid. Our findings have uncovered significant roles of PITPNC1 in mitochondrial phospholipid homeostasis and BAT thermogenesis.
Time Course and Clinical Significance of Hematoma Expansion in Moderate-to-Severe Traumatic Brain Injury: An Observational Cohort Study
Authors: Fletcher-Sandersjöö Alexander , Tatter Charles , Tjerkaski Jonathan , Bartek Jiri , Maegele Marc , Nelson David W. , Svensson Mikael , Thelin Eric Peter , Bellander Bo-Michael 
Published: September 2022

Abstract
Background
Preventing intracranial hematoma expansion has been advertised as a possible treatment opportunity in traumatic brain injury (TBI). However, the time course of hematoma expansion, and whether the expansion affects outcome, remains poorly understood. In light of this, the aim of this study was to use 3D volume rendering to determine how traumatic intracranial hematomas expand over time and evaluate its impact on outcome.

Methods
Single-center, population-based, observational cohort study of adults with moderate-to-severe TBI. Hematoma expansion was defined as the change in hematoma volume from the baseline computed tomography scan until the lesion had stopped progressing. Volumes were calculated by using semiautomated volumetric segmentation. Functional outcome was measured by using the 12 month Glasgow outcome scale (GOS).

Results
In total, 643 patients were included. The mean baseline hematoma volume was 4.2 ml, and the subsequent mean hematoma expansion was 3.8 ml. Overall, 33% of hematomas had stopped progressing within 3 h, and 94% of hematomas had stopped progressing within 24 h of injury. Contusions expanded significantly more, and for a longer period of time, than extra-axial hematomas. There was a significant dose–response relationship between hematoma expansion and 12 month GOS, even after adjusting for known outcome predictors, with every 1-ml increase in hematoma volume associated with a 6% increased risk of 1-point GOS deduction.

Conclusions
Hematoma expansion is a driver of unfavorable outcome in TBI, with small changes in hematoma volume also impacting functional outcome. This study also proposes a wider window of opportunity to prevent lesion progression than what has previously been suggested.
Circular RNA expression profile of systemic lupus erythematosus and its clinical significance as a potential novel biomarker
Authors: Li Wenyu , Fan Runge , Zhou Cheng , Wei Yue , Lin Shunsheng , Wen Sijian , Zeng Wen , Hou Wei , Zhao Cheng , Lin Youkun 
Published: September 2022

Abstract
Background
Circular RNAs (circRNAs) are a class of endogenous noncoding RNAs that are more abundant, specific, and highly organized than linear RNAs. Increasing evidence supports that circRNAs may serve as diagnostic biomarkers in many diseases, but their potential as biomarkers in systemic lupus erythematosus (SLE) remains unclear.

Objective
We investigated the critical circRNAs involved in SLE progression and explored their potential application as biomarkers in SLE.

Method
RNA sequencing was conducted on peripheral blood mononuclear cells (PBMCs) from 4 SLE patients and 4 healthy volunteers. CircRNA profile data were analyzed to identify differentially expressed circRNAs and visualized via R software. After screening, qPCR analysis of target circRNA expression was performed using PBMCs from 31 SLE patients and 35 healthy volunteers. Correlations between circRNA expression levels and the SLEDAI score were assessed via Spearman correlation analysis. Finally, the performance of circRNAs as biomarkers in SLE was examined by receiver operating characteristic curve analysis.

Results
The result identified six differentially expressed circRNAs between SLE patients and healthy controls: hsa_circ_0006689, hsa_circ_0070562, hsa_circ_0006117, hsa_circ_0007683, hsa_circ_0042519, and hsa_circ_0008647. The validation analysis showed differing relative expression levels of hsa_circ_0007683, hsa_circ_0042519, hsa_circ_0008647, and hsa_circ_0006689 between SLE patients and healthy volunteers (P < 0.05), and hsa_circ_0006689 expression in PBMCs correlated with the SLEDAI score (P < 0.05). Furthermore, addition of hsa_circ_0006689 expression increased the sensitivities of anti-dsDNA antibody and anti-Sm antibody levels for SLE diagnosis (from 29.03 to 61.30% and 32.26–71.00%, respectively).

Conclusion
Our results suggest hsa_circ_0006689 may be a useful circRNA biomarker for SLE diagnosis and prognosis.
Novel nano-biosorbent materials from thermal catalytic degradation of green pea waste for cationic and anionic dye decolorization
Authors: Rubangakene Norbert Onen , Elkady Marwa , Elwardany Ahmed , Fujii Manabu , Sekiguchi H. , Shokry Hassan 
Published: September 2022

Abstract
The recycling of waste materials in wastewater decontamination has been an attractive discipline in zero discharge and energy recovery. Biochar/zeolite nanocomposite has been successfully synthesized as a cheap and eco-friendly material from a solid fraction obtained from the thermos-catalytic conversion of green pea agriculture waste (Pisum sativum). A dark-whitish solid was obtained from thermal pyrolysis at 450 °C with a heating rate of 27 °C/min for 15 min that was further subjected to alkaline chemical activation. The synthesized composites have been examined using Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy dispersive X-ray (EDX), X-ray diffraction (XRD), transmission emission microscopy (TEM), and Brunauer-Emmet-Teller (BET) analyses. The successful preparation of biochar/zeolite nanocomposite was evident from characterization results with an average particle size of 30–40 nm with a high surface area of 15.3 m2/g. The material was evaluated as an eco-friendly adsorbent for decolorization of both cationic methylene blue dye (MB) and Congo red anionic dye (CR) using the batch technique. The influence of dosage, pH, temperature, initial dye concentration, and contact time were studied against the dye adsorption process. It was indicated that the material recorded maximum dye decolorization efficiencies of 87.5% at pH of 12 and 84.1% at pH of 2 for MB and CR, respectively. The optimum material dosage and contact time for dye decolorization were 5 g/l and 60 min, respectively. Thermodynamic parameters were calculated from the sorption process and revealed a negative charge of Gibbs free energy ($${\Delta G}^{o}$$

Δ
G

o

) an indication of spontaneity and thermodynamic favorability. Positive enthalpy and entropy demonstrated the endothermic behavior and the disorderliness. Equilibrium adsorption results best fitted to the Langmuir isotherm model, while MB and CR adsorption kinetics were pseudo-second-order reactions.
Evolutionary game analysis of three parties in logistics platforms and freight transportation companies’ behavioral strategies for horizontal collaboration considering vehicle capacity utilization
Authors: Deng Shuai , Zhou Duohong , Wu Guohua , Wang Ling , You Ge 
Published: September 2022

AbstractIn China, logistics platforms are an effective way to solve vehicle capacity utilization using information sharing. However, most logistics platforms do not possess operational sustainability due to excessive profit-seeking. To address this problem, conflicts of interest among freight transportation participants are discussed using a stakeholder approach. A three-player evolutionary game model (TEGM) is developed to analyze the interactions among freight carriers, freight shippers, and logistics platforms. Then, the asymptotic equilibrium and evolutionary stability strategies of the three-player game are analyzed. The results indicate that a high-level positive network externality is the driving force behind the logistics platform’s “high-level service”. A fairness payment incentive guarantees a “sharing” strategy for freight carriers and shippers. When the high-level positive network externality is limited and lower than a threshold value, there is no stable equilibrium point in the TEGM. A government tax incentive cannot change the freight carriers’ and shippers’ strategy to participate in this horizontal collaboration system, except for the logistics platform’s probability of providing “high-level service”. However, the behavioral strategies of the freight transportation participants can be changed to achieve the sustainability of freight transportation by reducing the value-added tax rate through the logistics platform and increasing the high-level positive network externality of the logistics platform and other participants’ perceived fairness through a payment incentive. Finally, suggestions for regulating the behaviors of freight transportation participants and promoting the sustainability of freight transportation are discussed.
Fundamental and practical approaches for single-cell ATAC-seq analysis
Authors: Shi Peiyu , Nie Yage , Yang Jiawen , Zhang Weixing , Tang Zhongjie , Xu Jin 
Published: September 2022

AbstractAssays for transposase-accessible chromatin through high-throughput sequencing (ATAC-seq) are effective tools in the study of genome-wide chromatin accessibility landscapes. With the rapid development of single-cell technology, open chromatin regions that play essential roles in epigenetic regulation have been measured at the single-cell level using single-cell ATAC-seq approaches. The application of scATAC-seq has become as popular as that of scRNA-seq. However, owing to the nature of scATAC-seq data, which are sparse and noisy, processing the data requires different methodologies and empirical experience. This review presents a practical guide for processing scATAC-seq data, from quality evaluation to downstream analysis, for various applications. In addition to the epigenomic profiling from scATAC-seq, we also discuss recent studies in which the function of non-coding variants has been investigated based on cell type-specific cis-regulatory elements and how to use the by-product genetic information obtained from scATAC-seq to infer single-cell copy number variants and trace cell lineage. We anticipate that this review will assist researchers in designing and implementing scATAC-seq assays to facilitate research in diverse fields.
A Socio-legal Approach to Language Use in Administrative Settings in Belgium’s Dutch-Language Area
Authors: Bernaerts Jonathan 
Published: September 2022

AbstractThis reflective article maps out the findings of a socio-legal study on language use in administrative settings in Belgium’s Dutch-language area. It explains how the author arrived at a socio-legal approach to this study object. Thereafter the article focuses on the methods used and the conceptual framework. It discusses the various methodological choices regarding data collection and the use of methods stemming from anthropology in this study. It also illustrates how anthropological literature on concepts such as discretion and multiple embeddedness provide conceptual tools for building a framework around which to structure and present the empirical data.The last part of the article sketches the findings of this socio-legal study. Drawing on the conceptual framework, it illustrates that even when practice deviates from statutory law, the relationship between the law and the practice cannot be easily captured in a dichotomic relationship. The author furthermore deduces some relevant findings in light of general human rights. The article concludes with some reflections on research that combines law and anthropology, both as separate disciplines and as a combined endeavor.
Re-reading Neulinger and Shuruk v. Switzerland: Bringing the Religious Dimension into View
Authors: Margaria Alice 
Published: September 2022

AbstractThis Article offers an anthropologically informed rereading of the landmark case Neulinger and Shuruk v. Switzerland, decided by the European Court of Human Rights (ECtHR) in 2010. This rereading is undertaken by “going beyond judgments” temporally—i.e., reconstructing the case from its origins to present—and spatially—i.e., looking at different sources of data and putting them into conversation with one another. This approach draws on anthropology both conceptually and methodologically. Not only does it address “case law” and “litigation” as creations of a variety of social and legal agents, constantly and meaningfully interacting with one another, but it also adopts a “litigant’s perspective” and creates space for acknowledging aspects of the lived experience of the applicants that have been marginalized in legal reasoning. By doing so, this Article shows that, from being strongly imbued with religious considerations, Neulinger and Shuruk came to assume a neutral framing when entering and progressing through the ECtHR. “Going beyond judgments” ultimately foregrounds the image of the Court as an institution addressing and doing different things to different audiences and stakeholders, and showcases some of the ways through which multi-perspectivity and efforts to “humanize the law” may be incorporated into case-law analyses.
Environmental Rights Between Constitutional Law and Local Context: Reflections on a Moving Target
Authors: Hanschel Dirk , Aguilera Bravo Mario G. , Dashpurev Bayar , Idris Abduletif Kedir 
Published: September 2022

AbstractEnvironmental rights such as the right to a sound environment and rights of nature, while playing an increasingly important role in global environmental governance and protection, frequently do not correspond to articulations of fundamental experiences of injustice by communities particularly affected by serious environmental degradation caused by, for example, extractive activities or major infrastructure projects. We present three empirically grounded case studies that employ concepts and methods from anthropology to demonstrate this. The work is still in progress, but sufficiently well advanced to present some findings. Our ethnographic research in Ethiopia and Mongolia reveals that vulnerable local communities take recourse to constitutional environmental rights far less often than expected. The reasons for this range from rule-of-law issues to local perceptions of vulnerability and relevant norms. Conversely, where environmental rights are demanded or claimed at the local level, they are often not translated adequately into the law of the state. Our case study on Ecuador, where rights of nature as a specific type of environmental rights have been included in the constitution, shows that transfers from local practice, while potentially having a transformative effect, may lead to conceptual selectivity, ambiguity, lack of clarity, and overlaps with existing state norms and, hence, redundancies. Environmental rights are, therefore, a moving target whose concrete added value hinges on context—as methods of law and anthropology serve to illustrate.
Feasibility of wearable camera use to improve the accuracy of dietary assessment among adults
Authors: Scott Judith L. , Vijayakumar Aswathy , Woodside Jayne V. , Neville Charlotte E. 
Published: September 2022

AbstractTraditional methods of dietary assessment are prone to measurement error, with energy intake often under-reported. The 24-h recall is widely used in dietary assessment, however, its reliance on self-report without verification of consumption can result in inaccuracies in true nutrient intake. Wearable cameras may provide a complementary approach to improve self-report accuracy by providing an objective and passive measure of food consumption. The purpose of the present study was to determine whether a wearable camera improves the accuracy of a 24-h recall compared with a 24-h recall alone in twenty adults aged 18–65 years. The study also explored limitations associated with wearable cameras. Participants wore the camera for 1 d and a 24-h recall was then conducted the following day, before and after viewing the camera images. Dietary data were analysed using Nutritics dietary analysis software, while eating habits were assessed by a self-report questionnaire. Energy and nutrient intakes were compared between the recall alone and the camera-assisted recall. Results showed a significant increase in mean energy intake with the camera-assisted recall compared with the recall alone (9677⋅8 ± 2708⋅0 kJ/dv. 9304⋅6 ± 2588⋅5 kJ/d, respectively,P= 0⋅003). Intakes of carbohydrates, total sugars and saturated fats were also significantly higher with the camera-assisted recall. In terms of challenges, there were occasionally technological issues such as proper positioning of the camera by the participants. In conclusion, reporting of energy and nutrient intake may be enhanced when a traditional method of dietary assessment, the 24-h recall, is assisted by a wearable camera.
Historical use of silver nitrate for the management of epistaxis – evidence-based practice?
Authors: Green M , Tailor H , Keh S 
Published: September 2022

AbstractObjectiveEpistaxis is one of the most common emergencies presenting to the ENT service, and silver nitrate cautery is the mainstay of epistaxis treatment in most centres worldwide. This review aimed to ascertain the historical evidence behind current common practice.MethodA review was conducted of historical published literature pertaining to epistaxis management.ResultsSilver in medicine dates back to 4000 BC, with silver nitrate first being used in 69 BC. Modern medical use for epistaxis is documented in case reports over the last 200 years.ConclusionThe precise origin and evidence-based practice of using silver nitrate for epistaxis is not well-established or understood. The mechanism of action is questionable; novel research of silver nitrate for this common ENT emergency presentation may be required.