bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hallazgos artroscópicos en lesiones de Maisonneuve
Authors: Rofrano Martín , Herrera Horacio 
Published: February 2022

Objetivo: Analizar los hallazgos de la artroscopia anterior de tobillo en lesiones de Maisonneuve tratadas con reducción bajo visualización artroscópica y fijación percutánea.
Materiales y Métodos: Se evaluó el registro de pacientes con lesiones de Maisonneuve agudas tratados con reducción bajo visualización artroscópica y fijación percutánea, entre mayo de 2013 y enero de 2019. Se analizaron los hallazgos artroscópicos buscados (lesiones condrales u osteocondrales, cuerpos libres intrarticulares, lesión de la articulación tibioperonea distal con inestabilidad o sin ella, y lesión del ligamento deltoideo con inestabilidad medial o sin ella).
Resultados: Se evaluaron 13 tobillos en 13 pacientes. Todos tenían lesión del ligamento tibioperoneo distal anterior e inestabilidad de la articulación tibioperonea distal. El 92,30% presentaba lesiones de estructuras mediales; el 76,9%, lesión completa e inestabilidad del ligamento deltoideo y el 15,38%, fracturas del maléolo tibial. Uno (7,69%) no tenía lesión medial. El 84,61% tenía lesiones condrales u osteocondrales y el 53,84% (7 pacientes), cuerpos libres.
Conclusiones: La lesión de Maisonneuve es una consecuencia de un trauma de alta energía y la incidencia de lesiones de estructuras intrarticulares (ligamentarias y de la superficie articular) es alta. La artroscopia es una herramienta de gran utilidad para identificar y tratar lesiones intrarticulares que, de otra manera, no serían reconocidas.
Modelo de hipotermia experimental en murinos para estudios de lesión medular
Authors: Sarotto Aníbal José , Contartese Daniela , Dorfman Verónica , Toscanini Agustina , Scheverin Nicolás , Besse Micaela , Larráyoz Ignacio , Rey-Funes Manuel , Martínez Alfredo , Loidl César Fabián 
Published: February 2022

Introducción: Los ensayos de hipotermia sistémica en murinos son costosos, debido a la complejidad de los sistemas. El objetivo de este estudio fue evaluar si el modelo de hipotermia sistémica exógena utilizado en nuestro laboratorio para la hipotermia ocular es útil para reducir significativamente la temperatura de la médula espinal en ratas adultas.
Materiales y Métodos: Se utilizaron 36 ratas Sprague-Dawley albinas macho de 60 días, distribuidas en dos grupos: grupo normotermia a 24 °C (n = 18) y grupo hipotermia (n = 18) en cámara fría a 8 °C durante 180 minutos.
Resultados: La temperatura rectal promedio fue de 37,71 ± 0,572 °C en el grupo normotermia y 34,03 ± 0,250 °C en el grupo hipotermia (p <0,0001). La temperatura medular promedio fue de 38,8 ± 0,468 °C en el grupo normotermia y de 36,4 ± 0,290 °C en el grupo hipotermia (p <0,0001).
Conclusiones: El uso de hipotermia sistémica en ratas de laboratorio parece ser un método prometedor para evaluar los mecanismos fisiológicos y patológicos que se desencadenan en la médula espinal. La exposición al frío en cámara genera hipotermia medular significativa en ratas adultas. Los resultados sugieren que podría ser un modelo adecuado de hipotermia medular de bajo costo.
“El goze de los derechos de ciudadano”: Elecciones y ciudadanía en la América Central, ca. 1770-1850
Authors: Dym Jordana 
Published: February 2022

Entre 1808 y 1850, las provincias y luego los estados independientes centroamericanos organizaron centenares de elecciones. Este artículo examina las constituciones y reglamentos electorales para entender la teoría electoral. Los ponen en conversación con los libros de elecciones, listados de votantes, periódicos, correspondencia, y otros documentos que revelan las prácticas a nivel municipal, estatal, y federal. El análisis muestra que el resultado sorprendente de un sistema que privilegió el voto indirecto y el poder del cuerpo legislativo en imponer resultados, era un compromiso ciudadano importante que, al final, preparó a la región para ampliar los derechos del ciudadano (al menos en papel) en la segunda mitad del siglo XIX.
Differences in AGEs-N-Carboxymethyllysine and Kidney Injury Molecule-1 in non-diabetic subjects, diabetic with and without diabetic nephropathy
Authors: Fajaryani Dwi , Rahayu Muji , Rachmawati Banundari 
Published: February 2022

Background: Diabetic nephropathy (ND) is a complication of diabetes mellitus (DM), characterized by persistent albuminuria. N-carboxymethyl lysine (CML) is the most extensive advanced glycation end products (AGEs), formed from the fructoselysine amadori. Kidney Injury Molecule 1 (KIM-1) is a type 1 transmembrane glycoprotein. The aim of the study is to analyze the differences in AGEs-CML and KIM-1 levels in the non-DM subject, DM without and with DN.Methods: A cross-sectional analytic observational study was conducted on 25 non-DM subjects (K1), 25 DM without DN (K2), and 25 DM withÂ DN (K3) in PROLANIS Semarang. AGEs-CML and KIM-1 levels were measured using the ELISA method. Inter-group AGEs-CML levels were analyzed using the One way ANOVA test, followed by post hoc Games-Howell. The levels KIM-1 between groups were analyzed using the Kruskal-Wallis test levels, followed by Mann Whitney post hoc test and p<0.05, were considered significant.Results: There were differences in AGEs-CML levels between K1 (739.89Â±227.37 ng/ml) and K3 (911.79Â±107.44) (p = 0.005), between K2 (798.82Â±153.03) and K3 (911.79 Â± 107.44) (p = 0.012) and there was no difference in K1 and K2 (p =0.535). There were differences in KIM-1 level between K1 [9.82 (5.99 â€“ 14.83) pg/ml] and K2 [15.31 (10.12 â€“ 30.21) (p <0.001)], between K1 [9.82 (5.99 â€“ 14.83)] and K3 [15.11 (8.27 â€“ 25.63) (p <0.001)] and there was no difference between K2 and K3 (p=0.720)Conclusion: The highest AGEs-CML levels were significantly found in the K3 group, followed by K2 and the lowest in K3. KIM-1 levels were significantly found in the K2 group, followed by K3 and the lowest in K1.
Risk score of contrast-induced nephropathy in patients after percutaneous coronary intervention
Authors: Limbong Morlim , Herry Yan , Ardhianto Pipin , Suhartono Suhartono 
Published: February 2022

Background: Contrast-induced nephropathy (CIN) after percutaneous coronary intervention (PCI) is still an issue in modern revascularization era. Recent risk stratification model used creatinine as biomarker which has some limitations. Increased â‰¥ 10 % of Cystatin-C after PCI has proven to be one of the earliest and accurate CIN after PCI biomarkers. The study aims to develop risk score based on predictors of contrast-induced nephropathy in patients after PCI with Cystatin-C as biomarkerMethods: A prospective cohort study of 129 patients after PCI at Dr. Kariadi General Hospital Semarang. Predictor analysis was carried out using bivariate chi-square test and multivariate logistic regression. The independent predictors obtained were then used as risk score variables. The Hosmer and Lemeshow calibration test and AUC ROC analysis for discrimination test tested the quality of the risk score.Results: There were 3 independent predictors used as the risk score variables: Hypotension (score 1), anemia (score 1), creatinine baseline >1.5 mg/dl (score 1). Patients with total score â‰¥1 have higher risk to have CIN after PCI. The risk score had a good quality with the Hosmer and Lemeshow calibration test > 0.05 and relative modest discrimination ROC AUC 0.700 (95% IK 0.585-0.815;Â p=0.001).Conclusions: A risk score for risk stratification CIN after PCI has been created. The score hasÂ good calibration and modest discrimination in predicting the risk of CIN after PCI.
A review of chest X-ray in pulmonary hypertension: correlation of right descending pulmonary artery diameter with mean pulmonary artery pressure
Authors: Nareswari Tara , Prihharsanti Christina Hari Nawangsih , Sukmaningytyas Hermina , Ningrum Farah Hendara , Satoto Bambang , Santoso Antonius Gunawan 
Published: February 2022

Background: Pulmonary hypertension is a condition which there is an increase in mean pulmonary artery pressure measured at â‰¥25 mmHg. The gold standard in diagnosing this condition is right heart catheterization. Enlargement of right descending pulmonary artery on chest radiographs is a sign of pulmonary hypertension. However, the value of radiographic measurements reported was diverse. The study analyzes the correlation between the right descending pulmonary artery (RDPA) diameter on chest radiographs and means pulmonary artery pressure on right heart catheterization to understand whether RDPA diameter on chest X-ray could be a predictor in determining the severity of pulmonary hypertension.Methods: Thirty-five subjects were reviewed to compare RDPA diameter from a chest X-ray on posteroanterior projection and mPAP value from the right heart catheterization. The correlation between them was analyzed using Pearson's correlation test.Â RDPA diameter cut-off point was defined using the ROC curve.Result: RDPA diameter and mPAP revealed a high positive correlation (p<0.001; r=0.824). The cut-off value of the RDPA diameter was 21.8 mm (sensitivity 81% and specificity 85.7%; AUC =0.9)Conclusion: The measurement of right descending pulmonary artery diameter on chest x-ray positively correlates with mean pulmonary artery pressure. Therefore, the diameter of the right pulmonary artery on the chest x-ray can predict the severity of pulmonary hypertension.
Pulsatile pseudoaneurysm: a delayed diagnosed with a risk of limb ischemic in toddler: a case report
Authors: Habibie Yopie Afriandi , Anggraini Vera 
Published: February 2022

Background: Pseudoaneurysm is a vascular injury complication in lower extremity thatâ€™s rarely been reported, especially in toddlers. Should it not appropriately treated, it can lead to worst conditions and even limb ischemic.Case description:Â a 3-year-old toddler, presented in the emergency room (ER) of Dr. Zainoel Abidin General Hospital (RSUZA) with bleed wound in the left limb persistent active bleeding. The shattered glass hit the patient On the physical examination, we found bleeding wound on the medial malleolus region of left limb, a pulsatile mass on the palpation, history of active bleeding was positive. To confirm the diagnosis, we performed CT angiography showing a sac shaped vascular lesion measuring 2.8 x 2.2 x 2.8 cm of proximal segment of the left posterior tibial artery, suggesting a pseudoaneurysm. We performed open surgery with excision procedure and a clot was found in medial malleolus region. As a result of open surgery, the left medial malleolus region is red, indicating a good blood flow and the patient discharged from hospital 4 days after surgery with a good result.Conclusion: Pseudoaneurysm resulting from vascular injuryÂ or iatrogenic injury can lead on various serious complications. If pseudoaneurysm is not appropriately treated, it can even threaten the patientâ€™s life.Â
A rare case of microcystic and macrocytic lymphangioma in 12-year-old girl
Authors: Lestari Wahyu , Hajar Sitti 
Published: February 2022

Introduction: Lymphangioma is an idiopathic digression in the lymphatic vessels morphogenesis. It is a lymphatic malformation that involves the lymphatic vessels of the superficial dermis. The lesions were observed since birth for 50% of the cases. Lymphangioma is typically rare of the lymphatic vessels disorder. This case report aims to explain lymphangioma, which is typically rare of the lymphatic vessels disorder. Case report: Our study reported a chief complaint in a 12-year-old girl was painless multiple small blisters on the left thigh and the left inguinal in the past 11 years. Physical examination revealed the groups of lobulated mass consist of erythematous papules, cysts, skin-colored and purplish papules, purplish macule, tense vesicles & reddish-brown crusts. The blisters were not itchy, followed by the slight swelling under the lesion of the left groin. They were skin-colored papules on the abdomen. It was also found that there was a hypertrophic scar on the upper side of the posteromedial side of the left thigh. Histopathology examination showed hyperkeratosis where the keratinocytes proliferation in the areas lined with endothelium. Eosinophilic amorphic mass found inside the lumen. There were hair follicles, sudoriferous glands and sebaceous glands. The proposed diagnosis was lymphangioma (combined microcystic and macrocystis lymphatic malformation) on the abdomen and soft tissue tumor on the left thigh and the buttock. The treatments were carbon dioxide (CO2) laser for lymphangioma and surgical excision for soft tissue tumor.Conclusion: Lymphangioma is a rare lymphatic vessel disorder that manifests on the superficial dermis. It is commonly found in children. This disease can be treated by CO2 laser.
A new innovation in topical diabetic foot ulcer; hyaluronic acid platelet-rich fibrin (HAPRF) gel - a study in inflammation and angiogenesis
Authors: Kartika Ronald W. , Alwi Idrus , Yunir Em , Waspadji Sarwono , Bardosono Saptawati , Immanuel Suzzana , Silalahi Todung , Sungkar Saleha , Rachmat Jusuf , Suyatna Franciscus D. , Reksodiputro Mirta Hediyati 
Published: February 2022

Background: Indonesia ranks 6th out of ten countries with the highest number of diabetes patients. An increase followed this condition in the prevalence of diabetic foot ulcers by around 15%. This study demonstrated the ability of combination of Platelet Rich Fibrin (PRF) and Hyaluronic Acid (HA) to reduce inflammation in diabetic foot ulcer (DFU) healing.Methods: In the baseline, all patients received the same treatment including wound debridement. There were 20 subjects divided into two groups; HAPRF and PRF. A part of sample was processed into lysate and stored in -80oC. The rest is applied as a topical therapy in DFU base on intervention. We analyzed the inflammation using two methods; swab in DFU and fibrin gel of HAPRF or PRF and ELISA on day-3 and day-7. We also measure the granulation index by digital photograph and analyze use ImageJ at the same time.Result: There were 20 diabetic patients with DFUs, performed analysis of IL-6 lysate gel HAPRF decrease significantly compare with PRF on day 3 (p= 0.038) and day-7 (p = 0.034). Granulation index evaluation, in HAPRF increase on day-3 (p = 0.043), day-7 (p = 0.049), and day-14 (p = 0.041).Conclusion: A-PRF +HA administration leads to reduce IL-6 levels, and accelerated wound healing of DFUs patients. HAPRF directly aids epithelialization and granulation index.
Exclusive breastfeeding behavior of adolescent mothers: A qualitative study
Authors: Yulyani Linda , Makiyah Sri Nabawiyati Nurul , Sulistyaningsih Sulistyaningsih 
Published: February 2022

Introduction: The overall rate of exclusive breastfeeding for infants under six months of age is only 41%. Many factors are known to contribute to unsuccessful exclusive breastfeeding, including maternal age. Adolescent mothers are associated with the incidence of early marriage. Currently, there has been an estimated number of early marriages of around 650 million in the world. This study aimed to explore the exclusive breastfeeding behavior of early marriage mothers. Methods: This is a qualitative study with a phenomenological approach. The data were collected through one-to-one interviews with seven adolescent mothers with babies aged 6-9 months as the research participants. Interviews were recorded, transcribed, translated and thematically analyzed using NVivo 12 trial version software. Results: This study found that the breastfeeding behavior of adolescent mothers can be grouped into 5 themes: perspectives and attitudes about exclusive breastfeeding, initial response of breastfeeding, knowledge of exclusive breastfeeding, challenges and difficulties in breastfeeding and the strategies to deal with these challenges, failure of exclusive breastfeeding. The results of this study also showed that of the seven participants, only one adolescent mother succeeded in her exclusive breastfeeding. Conclusions: Most of adolescent mothers with an early marriage who participated in this study had an unsuccessful exclusive breastfeeding of their babies. Therefore, it is necessary to have a comprehensive and sustainable education and counseling program on exclusive breastfeeding for adolescent mothers of early marriages by also considering the family involvement, particularly the husband and parents of these adolescent mothers.
The effect of using booklets on patients’ self-efficacy knowledge and interdialytic weight gain
Authors: Isnaini Nur , Styandini Dwi Agus , Ratnasari Dewi 
Published: February 2022

Introduction: The inability of patients with chronic renal failure to follow a diet is influenced by low self-efficacy. (Inter Dialytic Weight Gain) IDWG is used as a common measure of patient compliance, as it shows fluid retention that occurs between two hemodialysis sessions. This study aims to analyze the effect of providing education using a booklet on self-efficacy, and level of knowledge, and IDWG in hemodialysis patients.Methods: The research design was a pre-experimental design, with a group comparison design approach. The use of samples using accidental sampling. A sample of 48 respondents was divided into two groups: 25 and 23 respondents in the intervention and control groups respectively. The intervention group was given education using lecture and booklet methods for 45 minutes. The Control group was given education using the lecture method only. IDWG was measured by observing weight between hemodialysis sessions. The measurements of self-efficacy and level of knowledge were undertaken by employing a questionnaire. Wilcoxon test was used to determine the difference between the pre and post mean of the intervention group and the control group. Mann Whitney statistical test was used to determine the mean difference in the intervention and control groups on the variables of self-efficacy, level of knowledge, and IDWG.Results: Intervention group increased self-efficacy (p <0.05), increased knowledge (p <0.05) and decreased IDWG (p <0.05). Control group increase self-efficacy (p <0.05), increase knowledge (p <0.05), but not the value IDWG (p> 0.05).Conclusion: Education using booklets helps patients in increasing self-confidence, knowledge of CKD patient care including controlling fluid overload.
Determinants factors affecting the implementation of the COVID-19 health protocol in the community
Authors: Waliyanti Ema , Sulistiyaningrum Astri , Oktariza Atika , Nurrahaf Syifa Hafidhni , Satria Faudyan Eka 
Published: February 2022

Background: The COVID-19 case is a recent problem faced by people worldwide, including in Temanggung Regency. The local government has made various efforts to reduce the spread of the COVID-19 virus, namely by enforcing public health protocols such as physical distancing, prohibition of going to hometown, quarantine system, wearing masks, implementing handwashing and temperature measurement in every place to limiting community activities. However, many people have not obeyed the rules that the COVID-19 cases in the area increase. This study aims to identify the factors that influence the implementation of health protocols in the community in the Temanggung Regency.Method: This study used a qualitative method. Data were collected using in-depth interviews with 12 participants consisting of the community, village officials, and health workers selected using the purposive sampling technique. The instrument used was an interview guide. In addition, unstructured observations were carried out to identify the community's implementation of current health protocols. The data validity test was conducted by triangulating sources, methods, and peer debriefings. Thematic data analysis was carried out using Open code 4.02 software.Results: The results showed that the factors that influenced the implementation of health protocols to prevent the spread of COVID-19 in the community in Temanggung Regency included awareness of implementing health protocols, limited infrastructure, limited health personnel, monitoring of officers, perceptions of COVID-19, and public attitudes towards health protocols. Conclusion: Based on the results of this study, it is expected that it can be used as evaluation material for the community and local government in implementing health protocols to prevent the spread of the COVID-19 virus in the region.
Insulin resistance is associated with severe coronary artery stenosis in non-diabetic chronic coronary syndrome at Sanglah General Hospital, Bali
Authors: Wulandari Ni Luh Eka Sriayu , Artha I Made Junior Rina , Gotera Wira , Widiana I Gede Raka 
Published: February 2022

Background: The prevalence of insulin resistance (IR) increases worldwide due to the increasing number of the elderly population, obesity, and physical inactivity. IR modifies insulinâ€™s effect on blood vessel walls, with anti-atherogenic effects on insulin-sensitive and pro-atherogenic effects on IR conditions. However, the relationship between IR and the degree of atherosclerosis is still not conclusive. This study will examine the relationship between insulin resistance marker HOMA-IR and the degree of coronary artery stenosis using SYNTAX score measurements in non-diabetic subjects with the chronic coronary syndrome.Methods: The study was conducted on 68 subjects with non-diabetic chronic coronary syndrome taken by consecutive sampling. The diagnosis of the chronic coronary syndrome (CCS) is defined as subjects with significant â‰¥50% stenosis findings on coronary angiography. The degree of insulin resistance was measured using HOMA-IR and subjects were divided according to the HOMA-IR quartile. Data were analyzed in bivariate and multivariable modeling by SPSS version 25 for Windows.Results: The prevalence of severe coronary stenosis was 11.8%, 17.6%, 29.4% and 64.7% in quartiles 1, 2, 3 and 4, respectively. In multivariate analysis, it was found that quartile 4 subjects with cut-off value HOMA-IR â‰¥12.30 (OR 7.0; 95% CI=1.3-39.0; p=0.025) is an independent predictor of severe coronary stenosis, along with age â‰¥50 years (OR 13, 8; 95% CI=1.1-174.1; p=0.042), BMI â‰¥25 kg/m2 (OR 15.1; 95% CI=2.4-96.7; p=0.004), smoking (OR 18,0; 95% CI=2.0-160.5; p=0.010)Â Also found that statin therapy â‰¥2 months (OR 0.11; 95% CI 0.02-0.59; p=0.010) is an independent protective factor against severe coronary stenosis in non-diabetic CCS subjects.Conclusion: This study shows an independent association between IR and severe coronary stenosis in non-diabetic CCS subjects. This finding further strengthens clinical evidence of the direct pro-atherogenic effect of IR regardless of its glucose control effect and other metabolic syndrome components.