bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pattern of Contraceptive Use among the Married Couple of Rural Community in Cumilla District
Authors: Ahmed Zubaida , Ahmed Meah Monjur , Ali Ayet , Akhter Shahida , Akhter Rehana 
Published: June 2022

Background: Bangladesh has experienced a sevenfold increase in its contraceptive prevalence rate (CPR) in less than forty years from 8% in 1975 to 62% in 2014.Contraceptive practice acceptable moderately in society is said to be associated with socio-economic status, education and other factors. Population stabilization and a gradual lowering of population growth is the basic aim behind contraceptive practice. The population rate of Bangladesh in December, 2018 was 2.01%. The population density is 1252 per km2. Maximum of the population increased in the rural area, because they were not properly used the contraceptive methods. They seldom used contraceptive methods which influenced to increase the population. The purpose of the study is to examine the pattern of contraceptive use among the married couples of the rural area in Bangladesh. The objectives of the study is to determine the extent of awareness regarding contraception among the married persons, to estimate the perception of couples using contraceptive methods, identify the reasons for their adoption & non-adoption and to assess needs of contraceptive methods in rural area. Materials and
Methods: It was a descriptive type of cross sectional study, which was carried out in some selected villages at Laksham, Cumilla. Study populations were married women in reproductive age and married man. Purposive sampling was done. Sample size was 333. The number was identified on the basis of assumption. Pretested questionnaire and checklist were used for data collection.
Result: It was found that the age range of the respondents were 16 to 70 years, among the 333 respondents 34.2%were 20 to 29 years of age group, 86% were female &14% male.42.6% respondents were educated up to primary level. Majority of the respondents had 10,000 to 20,000 monthly family income. Among 333 respondents majority 28.5% had 3 children. 65.46% of the respondents were house wife, 80.5% respondents were using different types of contraceptive methods, 62.5% were using OCP, 3% IUCD, 3.9% barrier method or condom, 1.5% were in terminal method. 46.8% discontinue their previous contraceptive methods, 11.1% suffered from irregular period and 5.1% weight gain. 68.5% respondents were satisfied with their current contraceptive method, 36% felt need to adopt the contraceptive methods, 18.6% motivated by health workers, 25.2% influenced by the family members and 0.9% by the media. The number of children directly dependent on the educational qualification and monthly family income and are statistically significant (at p<0.05 and p<0.00).
Conclusion: Although success of the family planning program in Bangladesh has been widely acclaimed, many challenges still remain. Inter-spousal communication, counseling can ensure the most appropriate contraceptive methods for couples.
Central Medical College Journal Vol 5 No 1 Jan 2021 PP 35-40
Lipoprotein(a): An Independent Risk factor of Cardiovascular Disease
Authors: Karmakar Pijush , Farzana Taposhi , Jahan Iffat , Haque Mohammad Fazlul 
Published: June 2022

Background: Cardiovascular disease is currently one of the most common causes of morbidity and mortality in developed and developing countries. Many traditional risk factors such as age, gender, smoking, diabetes mellitus, dyslipidemia and hypertension play an important role in the development of vascular disorders. Lipoprotein (a) or Lp (a), an intriguing lipoprotein particle is also considered to be an important risk factor for the development of cardiovascular disease. Lp(a) is a LDL-like molecule consisting of an apolipoprotein B-100 (apo B-100) particle attached by a disulphide bridge to a unique protein, apolipoprotein(a)/ apo(a) which distinguishes it from LDL. Many epidemiological studies have reported the positive associations of Lp(a) concentration with atherosclerosis, coronary artery disease and stroke.
Central Medical College Journal Vol 5 No 1 Jan 2021 PP 51-58
Central de informações sobre a COVID-19: dúvidas e meios de difusão de informações confiáveis sobre a pandemia
Authors: Moura Gabrielly Oliveira Cunha , Silva Marcilio da Conceição , Santana Jonathan da Fraga , Santos Marilia Lima , Ferreira Lucas Martins da Silva , Silva Carla Maria Lima , Rocha Chiara Erminia da , Barros Izadora Menezes da Cunha , Brito Giselle de Carvalho , Unfer Taís Cristina 
Published: June 2022

Objetivos: Analisar as dúvidas dos usuários e os meios de comunicação usados pela CI- COVID-19 para a difusão de informações confiáveis sobre a pandemia, bem como a satisfação do usuário sobre o serviço. Métodos: Trata-se de um estudo com caráter quali e quantitativo, observacional e descritivo sobre a implementação da CI-COVID-19. A priori, os canais, meios e veículos de comunicação utilizados foram caracterizados. Em seguida, o conteúdo das dúvidas e fake news foi organizado por categorias temáticas e a frequência de distribuição de cada uma dessas categorias foi determinada. Além disso, as fontes de informação utilizadas foram identificadas e classificadas. Por fim, foi analisada a avaliação da satisfação do usuário a respeito do serviço prestado. Resultados: Ao longo de 365 dias de atividade, a CI-COVID-19 utilizou o canal eletrônico de comunicação, por meios visuais, audiovisuais e auditivos, através de mídias sociais. Nesse período, a CI-COVID-19 recebeu 330 solicitações e para respondê-las foram usadas 610 fontes de informação sendo 48,52% (n=296) classificadas como fontes primárias, 20,00% (n=112) como fontes secundárias e 31,48% (n=192) como fontes terciárias. Por último, os usuários do serviço se mostraram muito satisfeitos com o trabalho prestado. Conclusão: A CI-COVID-19 desempenhou um papel importante no combate à infodemia, utilizando diversos canais de comunicação para propagação de informações de qualidade e tendo os artigos científicos como principal fonte de informação sobre a pandemia causada pelo novo coronavírus. O elevado grau de satisfação dos usuários demonstra que o serviço prestado atendeu às necessidades da comunidade.
O uso das plantas medicinais no tratamento de situações odontológicas comuns na atenção primária à saúde
Authors: Rodrigues Fabrício Guimarães , Stroparo Jeferson Luis de Oliveira , Manzini Fernanda 
Published: June 2022

O uso das plantas para tratar os problemas de saúde é algo comum a todas as culturas humanas e o Brasil é privilegiado por ter uma grande biodiversidade de espécies vegetais. Muitas plantas já têm estudos que comprovam a sua eficácia para o tratamento de doenças humanas bastante comuns e outras plantas são muito usadas pela população, mas são carentes de estudos confiáveis que comprovem a sua eficácia. O uso da fitoterapia já é regulamentado na odontologia, contudo, são poucos os profissionais que usam este recurso na prática clínica e que realizam a prescrição de fitoterápicos aos seus pacientes. O objetivo desse trabalho é realizar uma revisão bibliográfica e demonstrar através de referências confiáveis que é possível prescrever o uso das plantas medicinais para o tratamento ou auxílio no tratamento das situações odontológicas mais comuns da Atenção Primária à Saúde (APS). São apresentadas plantas indicadas para uso no tratamento de cárie dental, doenças periodontais, lesões nos tecidos moles bucais e halitose, indicando para cada planta: nome popular, parte utilizada, forma de utilização, posologia, via de administração, propriedades e contraindicações. Essa revisão mostrou que é viável o uso das plantas medicinais na odontologia na APS, com respaldo científico, utilizando plantas de fácil acesso, valorizando o saber popular. Espera-se que esse trabalho sirva como base para a capacitação e educação permanente dos cirurgiões dentistas da rede municipal de saúde, possibilitando outras formas de atender as demandas dos pacientes da APS que buscam por serviços odontológicos.
Osteonecrose dos maxilares associado ao uso de bifosfonatos: revisão de literatura
Authors: Moura José Allysson de , Carvalho Filho Eduardo Sá Leitão de , Santana Marcos Alves , Vasconcellos Carlos Gilberto Pacheco Pessôa de 
Published: June 2022

Osteonecrose dos maxilares é uma doença devido a presença de osso necrosado, que se encontra exposto na região maxilofacial, havendo uma resistência por mais de oito semanas, em pacientes que façam uso do bifosfonatos ou terapias antirreabsortivas ou antiangiogênicas. Assim, o presente estudo contém revisão de literatura, expondo os principais fatores da osteonecrose em usuários de bifosfonatos. Para tanto, realizou-se um levantamento bibliográfico, com bases de dados dos PubMed, SciELO, LILACS e BIREME, entre os anos de 2016 a 2021. Com os estudos, observou- se que, apesar de não haver um protocolo definitivo para o tratamento, a ação de prevenir e executar um diagnóstico precoce reduz a morte de pacientes, com a adoção de terapias corretas, devendo essas serem realizadas com a assistência de odontólogo, para uma avaliação de cada caso, disponibilizado uma eficaz conduta odontológica, para todos os tratamentos.
Nandrolone decanoate reduces the positive effects of resistance training on cognition, anxious behavior, and hippocampal morphology in rats
Authors: Magalhães Caíque Olegário Diniz e , Oliveira Lucas Renan Sena de , Santos Stefanyne Teixeira , Mendes Bruno Ferreira , Dias Isabella Rocha , Cruz Poliany Pereira , Sampaio Kinulpe Honorato , Peixoto Marco Fabrício Dias , Sousa Ricardo Augusto Leoni de , Cassilhas Ricardo Cardoso 
Published: June 2022

AAs became popular among competitive athletes and the general population for recreational and performance purposes. The indiscriminate use of AAs occurs in supraphysiological doses and negatively affects cognition. Moreover, nandrolone decanoate (DECA) abuse may reduce the beneficial effects of resistance training (RT) on health. Objective: We aimed to investigate if DECA administration in supraphysiological doses interferes with the positive effects of RT on anxious behavior, memory, and morphology of neurons in the hippocampus of rats. Materials and Methods: Rats were randomly assigned into four groups (N= 12): Control (C); DECA (D); Trained (T) Trained+DECA (TD). EAA DECA was administered in daily supraphysiological doses of 15mg/kg during the 8 weeks of the RT protocol. All groups performed a maximum load test before and after the RT protocol; anxious behavior and memory tests were performed, and thereafter, rats were euthanized for morphologic analyses of the hippocampus. DECA produced an anxiogenic effect, worsened cognition and reduced the thickness of the grainy layer of the DG in the hippocampus. Moreover, DECA reduced the positive effects of RT on cognition and DG neurons. This is the first study showing that suprapharmacological doses of DECA reduce the positive effects of RT on memory and the thickness of the granular layer of the DG.
Benefícios do exercício físico aos portadores de diabetes
Authors: Dantas Julia Luiz de Sousa , Rodrigues Liz Paola , Azeredo João Paulo Silva 
Published: June 2022

Introdução: O exercício físico é importante para manutenção da saúde das pessoas, o que é desconhecido para algumas pessoas é que a prática regular do exercício físico é fator determinante no tratamento de diversas patologias entre elas o diabetes melittus tipo I e II. A diabetes é uma doença endócrina caracterizada por altos níveis de glicose sanguínea (hiperglicemia), tal situação pode gerar desequilíbrios e consequentes danos a tecidos e órgãos vitais. Objetivo: demonstrar quais são os benefícios que o exercício físico traz para o controle glicêmico aos portadores de diabetes mellitus tipo I e II. Metodologia proposta: Este trabalho trata-se de uma revisão integrativa da literatura,realizada através de pesquisas em artigos científicos presentes em bases de dados tradicionais do conhecimento em saúde como: PubMed, SciELO, Science Direct, CAPES, entre 2015 e 2021. Resultados e discussão: vemos que a prática de exercícios físicos é determinante em todos processos de homeostase corporal e contribui diretamente para minimizar os efeitos decorrentes de quadros envolvendo a diabetes, e a importância do farmacêutico na assistência a saúde. Conclusão: Devido e a grande incidência da diabetes no contexto da saúde mundial, é importante enfatizar que a atividade física é fundamental para a saúde, a assistência farmacêutica também vem ganhando destaque para que o diabético se mantenha saudável.
Efficiency and safety of laparoscopic ventral mesh rectopexy (a systematic review)
Authors: Khitaryan A. G. , Golovina A. A. , Kovalev S. A. , Burtsev S. S. 
Published: June 2022

Aim: to assess the efficacy and safety of laparoscopic ventral mesh rectopexy in patients with rectocele and rectal prolapse. Materials and methods: a systematic review of the literature on the efficacy and safety of laparoscopic ventral mesh rectopexy in patients with rectocele and/or rectal prolapse. After compiling a search query, 2716 publications were found in the PubMed, MEDLINE, EMBASE, Scopus, Cochrane library, CENTRAL, ISI Web of Science and eLibrary databases. Twenty-four papers were selected according to the inclusion criteria for the review, with a total number of 2101 operated patients. Results: the follow up period after surgery ranged 30.1 (12-74) months. In 20 of 34 studies, the median age of patients was over 60 years, with a median of 62.1 years. The mean operative time was 122.3 minutes (85 to 200 minutes). Complications were revealed in 138 patients (6.5 % observations), recurrence — in 4.1 %. A significant improvement in the symptoms of obstructive defecation was noted in 79.6 %. Conclusion: laparoscopic ventral mesh rectopexy is an effective method for posterior pelvic floor compartment prolapse in terms of both anatomical and functional results. It is safe and has a low risk of complications. However, further research is required to develop indications for the use of this proctdure as a “gold standard”.
CT and MRI diagnostics of desmoid fibroids in familial colon adenomatosis
Authors: Zarodnyuk I. V. , Belov D. M. , Kuzminov A. M. , Vyshegorodtsev D. V. , Korolik V. Yu. , Pikunov D. Yu. , Savelyeva T. A. 
Published: June 2022

Objective: to study the features of CT and MRI diagnostics of desmoid fibroids (DF) in familial colon adenomatosis (SATC). Patients and methods: the study included 35 patients with desmoid fibroids (DF) in familial colon adenomatosis (SATC). All patients were examined using computed tomography (CT) and magnetic resonance imaging (MRI) with intravenous contrast. Localization, size, growth pattern, prevalence of DF, features of contrast and intensity of the MR signal on T2-VI and post-contrast T1-VI were evaluated. Twenty-five (71.4%) patients were observed in dynamics, including during systemic therapy. Results: in 21 (60.0 %) patients, a lesion of only one anatomical area was detected, and in 14 (40.0%) cases, a combined lesion of different anatomical zones was noted. In the majority of observations (33/35, 94.4 %) desmoid fibroids were detected in the mesentery and mesentery root of the small intestine, including with a combined lesion. The majority of patients (24/35, 68.6%) were diagnosed with a diffuse nodular form of growth; 13 (37.1%) had a nodular form and 6 (17.1%) had a diffuse form. Twenty-five patients (25/35, 71.4%) were repeatedly re-examined using CT (13/35, 37.1%) and MRI (12/35, 34.3%), in particular during systemic therapy. Conclusion: CT and MRI are the basic methods for detecting DF in SATC, allowing to determine the nature of tumor growth, to assess the prevalence of the tumor process and the degree of involvement of adjacent organs and structures. In dynamic observation and evaluation of the response of a desmoid tumor to systemic therapy, MRI has greater diagnostic capabilities compared to CT, since it takes into account not only the size of the desmoid, but also the intensity of the MR signal on T2-VI and the nature of the accumulation of contrast agent on post-contrast T1-VI with fat suppression.
Reconstruction of the rectovaginal septum with a W-mesh for rectocele
Authors: Lukianov A. S. , Biryukov O. M. , Titov A. Yu. , Mudrov A. A. , Nikishin T. V. , Kostarev I. V. 
Published: June 2022

Aim: to assess of late results of original method of rectocele repair with non-absorbable polypropylene W-form mesh. Patients and methods: the pilot study included 37 patients which underwent surgery for rectocele repair using original technique of W-mesh. The late results were assessed in 21 (56.6 %) of them ≥ 6 month after surgery. Before the surgery and 6 months after, patients underwent a clinical assessment of symptoms. Specialized questionnaires for assessment of constipation (Colonic evacuation disorder scale, PFDI-20, Cleveland Clinic Constipation Score) were used. Defecography and anorectal manometry were performed before and in 6-months after surgery for evaluation of pelvic floor disorders. Results: no obstructive defecation symptoms were revealed in 85.7% of patients 6 month after surgery.In ≥ 6 months after surgery all questionnaires showed decrease in scores by more than 2 times. Comparison of the results before and 6 months after the surgery showed significant differences for all questionnaires (p < 0.0001). According to defecography performed before and after the surgery a significant reduction (p < 0.05) of rectocele depth, time of rectal voiding (decreased by 1.5 times) and residual volume of contrast agent (decreased by 2.5 times) were revealed. There are no severe complications requiring re-operation were observed. Conclusion: transvaginal mesh repair of symptomatic rectocele demonstrated good clinical results 6 months after surgery. Good results were revealed in 85,7 % of patients confirmed by specialized questionnaires and defecography.
Space Charge Dynamics in Epoxy Resins Under the Influence of a Long-Term High Electric Field at Various Temperatures
Authors: Zhang Hongliang , Li Kun , Jin Hai , Li Kangle , Li Xiaonan , Liu Peng , Peng Zongren 
Published: June 2022

As the main insulating material of an ultra-high voltage (UHV) resin impregnated paper (RIP) bushing, epoxy resin accumulates space charge under the DC voltage, which would affect the insulation properties of the bushing. In this article, the evolution of space charge accumulation and dissipation within the epoxy resin samples was measured under the influence of a long-term (24 h) electric field of 60 kV/mm at 40°, 60°, 80°, and 100°C. The experimental results show that the space charge transport in the epoxy sample was a long-time dynamic process. When the temperature was not greater than 60°C, only homocharge accumulation was observed within the samples, and the space charge distribution did not reach a stable state even after 24 h of voltage application. When the temperature was not lower than 80°C, the positive heterocharge accumulation was observed at the interface between cathode and epoxy. Through analysis by fitting and numerical simulation, it was verified that the positive heterocharge accumulation was caused by the limitation of the hole extraction, and the transport of holes within the samples obeyed the jump conductance model.
Exploring HSP90 as a Biomarker for Marine Heatwaves in Pinctada maxima
Authors: Masanja Fortunatus , Xu Yang , He Guixiang , Liang Feilong , Liu Xiaolong , Yang Ke , Mkuye Robert , Liang Jian , Deng Yuewen , Zhao Liqiang 
Published: June 2022

Many species, particularly marine organisms, are becoming more vulnerable to marine heatwaves due to climate change. Marine species anticipate perishing during marine heatwaves, but there is a growing interest in learning why some can resist. Using Pinctada maxima as a model species, we were able to clone a full-length cDNA encoding HSP90 with a calculated open reading frame of 2031 residues of amino acids and a molecular mass estimate of 78.08 kD to understand better the effects of marine heatwaves on the HSP90 gene expression in pearl oysters. The sequence of amino acids in P. maxima HSP90 was quite similar to the HSP90 families of Pinctada fucata martensii. At 32°C and 36°C, the expression of PmHSP90 significantly expressed and reached its highest level at 6 h, implying that in pearl oysters’ response to acute marine heatwaves, HSP90 expression rapidly increased. Pearl oysters’ temperature response was relieved, as best demonstrated by the dramatically reduced expression levels of PmHSP90 in the frequently reoccurring marine heatwaves event. Using these findings, it is possible to predict acute and repeated marine heatwaves in pearl oysters using P. maxima HSP90 as a molecular biomarker.
Brain Structural and Functional Dissociated Patterns in Degenerative Cervical Myelopathy: A Case-Controlled Retrospective Resting-State fMRI Study
Authors: Zhou Yi , Shi Jiaqi 
Published: June 2022

BackgroundPrevious studies have shown the whole-brain global functional connectivity density (gFCD) and gray matter volume (GMV) alterations in patients with degenerative cervical myelopathy (DCM). However, no study aimed to investigate the associations between the spatial patterns of GMV and gFCD alterations in patients with DCM.MethodsStructural data and resting-state functional MRI data of 35 DCM patients and 35 matched healthy controls were collected to assess their gFCD and GMV and investigate gFCD and GMV alterations in patients with DCM and their spatial pattern associations.ResultsIn our current study, significant gFCD and GMV differences were observed in some regions of the visual system, sensorimotor cortices, and cerebellum between patients with DCM and healthy controls. In our findings, decreased gFCD was found in areas primarily located at the sensorimotor cortices, while increased gFCD was observed primarily within areas located at the visual system and cerebellum. Decreased GMV was seen in the left thalamus, bilateral supplementary motor area (SMA), and left inferior occipital cortices in patients with DCM, while increased GMV was observed in the cerebellum.ConclusionOur findings suggest that structural and functional alterations independently contributed to the neuropathology of DCM. However, longitudinal studies are still needed to further illustrate the associations between structural deficits and functional alterations underlying the onset of brain abnormalities as DCM develops.