bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pathological anatomy of the new coronavirus infection COVID-19 according to autopsy materials 2020
Authors: Rybakova M. G. , Fionik A. M. , Danilova D. M. , Myurzep A. E. , Sycheva A. M. , Tsaregorodtseva A. D. 
Published: April 2022

Introduction. Organ lesions due to the new coronavirus infection are determined by several factors: direct cytopathic effect of SARS-CoV-2, release of an unbalanced amounts of proinflammatory cytokines leads to systemic damage of the vascular endothelium and increasing hypoxia. These factors in total result in organ dysfunction.Methods and materials. We examined 96 pathological studies’ protocols of patients who died from the PCR-confirmed new coronavirus infection. Histological slides stained with hematoxylin and eosin were also analyzed.Results. Macroscopical and microscopical changes seen mostly in lungs, myocardium and other internal organs were described. We reviewed main causes of death (pulmonary and cardiopulmonary failure, multiple organ dysfunction syndrome) and most common concomitant diseases (diabetes mellitus, essential hypertension, obesity). The morphological features of diffuse alveolar damage in the acute and proliferative phases were described in detail. Taken together with the synchronous involvement of the microvasculature in the pathological process it became the main cause of death. The most severe structural changes in lungs were seen after 20 days of disease. These changes were correlated with dysregenerative metaplastic and dysplastic processes. Processes of disturbed regeneration reflect both the severe viral transformation of the alveolar epithelium and the fact that regeneration developed under mechanical ventilation.
Pengaruh Pengetahuan Kewirausahaan, Orientasi Kewirausahaan, dan Inovasi terhadap Keberhasilan UKM Alumni dan Mahasiswa Universitas Tarumanagara
Authors: Merline Merline , Widjaja Oey Hannes 
Published: April 2022

Penelitian ini mempunyai tujuan untuk mengetahui pengaruh pengetahuan kewirausahaan, orientasi kewirausahaan, dan inovasi terhadap keberhasilan usaha. Sampel yang dipakai dalam penelitian ini adalah alumni dan mahasiswa Universitas Tarumanagara yang memiliki UKM. Teknik pengambilan sampel yang digunakan dalam penelitian ini adalah non probability sampling dengan teknik pemilihan sampel dengan purposive sampling. Sebanyak 100 responden terkumpul melalui kusioner yang dibagikan. Penelitian ini menggunakan metode structural equation modelling (SEM) untuk menganalisis data dan aplikasi SmartPLS versi 3.3.3 untuk mengolah data. Hasil yang didapatkan dalam penelitian ini adalah pengetahuan kewirausahaan, orientasi kewirausahaan, dan inovasi memiliki pengaruh positif yang signifikan terhadap keberhasilan usaha. The purpose of this study is to determine the effect of entrepreneurial knowledge, entrepreneurial orientation, and innovation on business success. The sample used in this study were alumni and students of Tarumanagara University who have SMEs. The sampling technique used in this study is non-probability sampling and purposive sampling. A total of 100 respondents were collected through the questionnaire that was distributed. This study uses the structural equation modeling (SEM) method to analyze the data and the SmartPLS version 3.3.3 application to process the data. The results obtained in this study are entrepreneurial knowledge, entrepreneurial orientation, and innovation have a significant positive effect on business success.
Saturação Venosa Central de Oxigênio em relação à Sepse: revisão integrativa de literatura
Authors: Oliveira Ana Beatriz de Almeida , Oliveira Carla Resende Vaz , Reis Bruno Cezario Costa 
Published: April 2022

Objetivo: Revisar a literatura sobre o uso da saturação venosa e central de oxigênio na sepse. Métodos: Tratou-se de uma revisão integrativa da literatura na base de dados: PubMed. Os critérios de inclusão consistiram em artigos publicados nos últimos cinco anos, nos idiomas inglês, espanhol e português, que abordassem a temática proposta. Excluíram-se estudos de revisão, teses, dissertações, artigos repetidos e que não correspondiam ao tema. Resultados: Após o levantamento dos artigos através dos bancos de dados e seguindo os critérios de inclusão pré-estabelecidos, obtivemos um total de 32 estudos que foram lidos na íntegra. Apenas 15 foram utilizados e os resultados estão expostos em quadro. Considerações finais: Observou-se que a saturação venosa de oxigênio em pacientes críticos apresenta um valor diagnóstico, terapêutico e prognóstico. Não há nenhum argumento fisiológico para atingir valores específicos de SvO2 onde a otimização de um a três dos quatro componentes de SvO2 pode produzir uma dependência clara com o quarto. Vários estudos randomizados recentes falharam em mostrar qualquer melhora na sobrevida desses pacientes apesar de demonstrarem o seu benefício na sepse.
Isolated idiopathic myositis of the inferior oblique muscle biopsied through lateral orbitotomy
Authors: Tsutsumi Satoshi , Izumi Hiroshi , Ishii Hisato 
Published: April 2022

Background:
Isolated orbital myositis of the inferior oblique muscle (IObM) is rare, with few reported cases.

Case Description:
A 65-year-old woman was aware of double vision and left dacryorrhea for 2 months. At presentation, the patient showed mild restriction on the downward gaze. In addition, a subcutaneous mass was palpated on the left eyelid. The blood examination showed normal findings. Cranial computed tomography revealed an isodense mass in the left orbit, located in the inferior, inferolateral, and posterior aspects of the bulb. On magnetic resonance imaging, the mass was well-demarcated, appeared isointense on both T1- and T2-weighted imaging, and was intensely enhanced after intravenous infusion of gadolinium. The patient underwent biopsy through lateral orbitotomy. Microscopically, the resected specimen showed sheet-like proliferation of small round nonneoplastic cells. These cells were positively immunostained for both B- and T-lymphocyte markers. Therefore, we diagnosed the patient with isolated idiopathic myositis of the IObM. The patient was managed with steroids, which resulted in a remarkable resolution of her orbital symptoms.

Conclusion:
Biopsy findings should be considered when the presentation of orbital myositis is atypical. Lateral orbitotomy may provide a useful surgical window when approaching the posterior belly of the IObM.
Spinal deformity correction in ankylosing spondylitis
Authors: Maggio Dominic , Grossbach Andrew , Gibbs David , Moranville Robert , Toop Nathaniel , Xu David , Viljoen Stephanus 
Published: April 2022

Background:
Ankylosing spondylitis (AS) is a complex, debilitating disease with few available medical therapies in its later stages.

Methods:
We reviewed current clinical approaches for caring for AS patients with an emphasis on the risks and outcomes associated with surgical intervention.

Results:
It is critical to understand the natural history and surgical outcomes of patient with AS. Surgery is not without risks, as a vertebral body osteotomy is often required to re-establish spinopelvic equilibrium. However, surgery can lead to clinical improvements in pain, disability, cardiac function, respiration, digestion, and sexual activity.

Conclusion:
Deformity correction for AS should be carefully considered in symptomatic patients.
PERANCANGAN RUANG TERBUKA PUBLIK DI KECAMATAN PONTIANAK UTARA DENGAN PENDEKATAN DESAIN UNIVERSAL
Authors: Diartini Livia , Andi Uray Fery , Purnomo Yudi 
Published: April 2022

The uneven distribution of the population in North Pontianak District has resulted in rapid development. This causes less attractiveness in the North Pontianak District area compared to other Pontianak City Districts. The limited infrastructure and public service facilities and the large number of people from children to the elderly with special needs led to the birth of a design idea that is able to answer all problems, namely by presenting a Public Open Space that accommodates community activities with a universal design approach (design for everyone). ). Universal design is a design concept that is intended for everyone regardless of differences. The design concept is applied to the design of products, the environment, and even a public open space that can facilitate the whole community. The purpose of designing public open spaces is to meet the needs of the people of North Pontianak District and its surroundings regardless of differences in background, culture, language, knowledge and level of physical ability. The method used is the design thinking method, which is a method that collects data and looks for solutions in a design. Design thinking is a method of solving problems for users (users). The Design of Public Open Spaces in North Pontianak District with a Universal Design Approach creates a public open space that applies seven (7) universal design principles. 7 universal design principles in the form of products, facilities and spaces designed based on the Universal design approach.
SEMINARI TINGGI MAZMUR 21 KALIMANTAN BARAT
Authors: Tendiono Michael Vica , Khaliesh Hamdil , Caesariadi Tri Wibowo 
Published: April 2022

Seminary is a place for Christian religious education to form and educate prospective Christian clergy. The seminary is equipped with various educational support facilities, because it is a special education that focuses on theological/religious education. Seminary facilities in the Pontianak City area are currently considered to be less than optimal, both in terms of quantity/quantity, and quality of facilities. The purpose of this design is to produce the design of educational facilities and religious tourism that is able to accommodate the needs of users and visitors in the form of facilities and infrastructure. The design object focuses on the Bukit Doa Psalm 21 area, Anjongan, Mempawah. The method used in this design is observation, comparison, and analysis. The author will conduct field observations at seminaries and retreat houses in Pontianak, as well as interviews with related parties. The design focus is on identifying seminary facilities and the need for infrastructure. The theme that will be focused on this design is contextual architecture which focuses on linking new buildings with the environment. References to contextual architecture and similar buildings are taken from various sources. The collected case studies will later become a design guide, ideas and solutions to design problems. The seminary design concept is in the form of a spatial program schematic and site analysis which results in the identification of the required facilities and a schematic design of the seminary area and building. The final result of the design of the West Kalimantan Psalm 21 High Seminary is the the seminary area and building that has complete infrastructure that is able to accommodate educational activities and religious tourism, but also has a connection with the surrounding environment.
Praktek Kecurangan (Fraud) dan Modusnya di Lingkungan Usaha PT JOY
Authors: Safuan Safuan , Lesmana M. Azmi 
Published: April 2022

This research was conducted to determine whether there was fraud that occurred in the PT JOY business environment, the types of fraud and the modes of fraud carried out by individual employees. The method used in this research is a qualitative approach, with a case study. Most of the fraud committed by unscrupulous employees in the PT JOY business environment occurs due to weak systems and lack of supervision from company management. The author hopes that the results of the research will be used as material for evaluating management systems and policies because if proven, of course this fraud will cause a large potential loss for the company.
STRATEGI PEMBELAJARAN VOKAL UNTUK ANAK-ANAK DI PURWACARAKA MUSIC STUDIO MARGOREJO SURABAYA
Authors: Setyawati Zuly Indah , Yanuartuti Setyo 
Published: April 2022

Purwacaraka Music Studio (PCMS) merupakan lembaga musik nonformal yang didirikan oleh komponis dan musisi Indonesia yaitu Purwacaraka. PCMS menghasilkan banyak musisi khususnya penyanyi serta meraih banyak prestasi. Hal tersebut tentunya dipengaruhi oleh peran tenaga pendidik yang memiliki latar belakang berpengalaman di bidang musik serta mampu mengembangkan bakat siswa. Tujuan penelitian ini adalah menganalisis strategi dan hasil pembelajaran vokal untuk anak-anak di PCMS Margorejo Surabaya. Penelitian ini termasuk dalam jenis penelitian kualitatif dengan menggunakan teknik pengumpulan data melalui observasi, wawancara terstrukur, dan dokumentasi. Analisis data dilakukan secara sistematis meliputi reduksi data, penyajian data dan penarikan kesimpulan. Hasil pembahasan menyatakan bahwa strategi pembelajaran vokal mengoptimalkan, persiapan pembelajaran, penggunaan media pembelajaran, penyampaian materi pembelajaran. Strategi tersebut telah menjadikan siswa lebih efektif dalam proses pembelajaran vokal terkhusus pada usia anak-anak. Hal tersebut dapat dilihat dari hasil belajar siswa yang meliputi aspek-aspek penilaian yang terdiri dari aspek sikap (kehadiran, kedisiplinan, bersosialisasi, keaktifan) serta aspek keterampilan (pernafasan, vokalisi, artikulasi, sikap badan, miking, intonasi, phrasering, ekspresi pada saat menyanyikan lagu). Berdasarkan evaluasi tersebut pembelajaran vokal pada anak-anak di PCMS memiliki kualitas yang baik dan tenaga pendidiknya juga profesional dalam mengajar siswa. Hal ini dibuktikan dengan melihat hasil pembelajaran pada laporan lembar belajar siswa dengan nilai yang baik.
PEMBELAJARAN SENI TARI KELAS XI DI SMKN 12 SURABAYA PADA MASA PANDEMI COVID-19
Authors: Kusuma Putri Nabilla Nur Kasih , Trisakti Trisakti 
Published: April 2022

SMKN 12 Surabaya adalah lembaga pendidikan formal di Surabaya. Penelitian di SMKN 12 ini bertujuan untuk mendeskripsikan pembelajaran tari Jawa Timur, kendala pembelajaran dan hasil belajar tari Jawa Timur 1 di Kelas XI pada masa pademi Covid-19. Penelitian ini menggunakan metode kualitatif dengan objek penelitian adalah pembelajaran praktik seni tari pada mata pelajaran tari Jawa Timur 1 dengan materi Remo Putri. Teknik pengumpulan data dilakukan melalui observasi, wawancara, dan dokumentasi. Hasil penelitian bahwa pada masa pandemi covid-19, Pembelajaran tatap muka berfokus guna meningkatkan kepahaman siswa. Jadi dimasa pandemi ini tidak menjadi penghalang untuk siswa memperoleh ilmu. Proses pembelajaran tetap berlangsung di SMKN 12 Surabaya dan waktu tatap muka berkurang dari 4 kali menjadi 2 kali tatap muka. Pembelajaran tatap muka dilakukan dengan menggunakan protokol kesehatan. Pembelajaran menggunakan metode demonstrasi dengan media video pembelajaran. Hasil belajar siswa di masa pandemi ini cukup baik dan mendapat kontroling nilai dari guru untuk siswa. Kendala dalam proses pembelajaran pada masa pandemi adalah berkurangnya waktu yang berdampak materi yang diberikan oleh guru terhambat, oleh karena itu guru membuat media video pembelajaran untuk dipelajari dirumah. Sedangkan kendala yang dialami siswa adalah dalam hal menerima materi pembelajaran dari video pembelajaran kurang jelas dan menyebabkan belajar mandiri tidak dapat berjalan dengan baik.
PENGEMBANGAN KREATIVITAS SENI TARI MELALUI PEMBENTUKAN KELAS SENI DI SMPN 2 PAMEKASAN
Authors: Ulfa Ayu Mariya , Handayaningrum Warih 
Published: April 2022

SMP Negeri 2 Pamekasan merupakan sekolah yang mampu membentuk kelompok kelas bakat dan minat, khusunya Kelas Seni. Awal mula terjadinya pembentukan kelas seni disebabkan tidak adanya ruang dan wadah untuk menyalurkan bakat siswa padahal banyak siswa yang unggul dan berprestasi dalam bidang seni tari. Atas dasar inilah yang mendorong peneliti untuk mengkaji lebih dalam mengenai pengembangan kreativitas seni tari. Penelitian ini menggunakan penelitian kualitatif. Subyek penelitian adalah guru dan siswa kelas seni. Teknik pengumpulan data meliputi: studi pustaka, observasi, wawancara tidak terstruktur dan dokumentasi. Teknik analisis data menggunakan pengumpulan data dan reduksi data. Teknik triangulasi yang digunakan dalam penelitian ini adalah triangulasi metode, triangulasi sumber dan triangulasi waktu. Hasil penelitian menunjukkan bahwa proses pembelajaran dilakukan dengan 2 tahap yaitu perencanaan dan pelaksanaan. Perencanaan pembelajaran diwujudkan dengan guru membuat RPP, sedangkan pelaksanaan pembelajaran diwujudkan dengan menyusun komponen pembelajaran. Pengembangan kreativitas dilakukan dengan menciptakan karya tari yang dilakukan dalam 4 tahapan yaitu mencari ide, eksplorasi, penyusunan dan penyajian. Evaluasi pembelajaran menggunakan instrumen penilaian dan indikator kreativitas. Instrumen penilaian menggunakan 3 bentuk yaitu penilaian unjuk kerja, penugasan dan tertulis. Dengan demikian pembentukan Kelas Seni telah memberikan kontribusi dan peranan yang besar dalam mendukung bakat siswa dan memberikan wadah untuk menyalurkan bakat kreatif.
PEMBELAJARAN GAMELAN JAWA MENGGUNAKAN APLIKASI “GATOEL” DI SMAN 1 KAWEDANAN MAGETAN
Authors: Sintia Dinni Ella , Yanuartuti Setyo 
Published: April 2022

Dalam proses pembelajaran, pendidik selalu memberikan pembelajaran yang menarik kepada peserta didiknya. Salah satunya pembelajaran Gamelan Jawa menggunakan aplikasi “Gatoel” yang diterapkan pendidik di SMAN 1 Kawedanan Magetan. Media yang digunakan smartphone berbasis OS Android. Hal tersebut dikarenakan kurangnya sarana prasarana sekolah yaitu Gamelan Jawa, sehingga pendidik berupaya memberikan materi tentang pengenalan bermain Gamelan Jawa melalui sebuah aplikasi yang terdapat pada smartphone Android. Tujuan penelitian ini untuk mengetahui strategi dan hasil pembelajaran Gamelan Jawa menggunakan aplikasi “Gatoel“ di SMA N 1 Kawedanan Magetan. Metode yang digunakan dalam pembelajaran ini adalah metode ceramah, tanya jawab dan pemberian tugas, serta metode praktik. Model dalam pembelajaran ini discovery learning, dengan pendekatan scientific learning. Hasil penelitian dan pembahasan menunjukkan bahwa strategi pembelajaran Gamelan Jawa menggunakan aplikasi “Gatoel” dapat berjalan dengan baik dan sesuai prosedur pembelajaran. Hal ini dibuktikan tingkat pemahaman materi yang baik serta antusias peserta didik dalam pembelajaran ini. Hasil pembelajaran Gamelan Jawa menggunakan aplikasi Smartphone “Gatoel” di SMAN 1 Kawedanan sudah memenuhi pencapaian tujuan dalam pembelajaran. Terbukti respon 56% peserta didik sangat baik dan tes akhir menunjukkan bahwa nilai rata-rata > 80 peserta didik adalah 83% dalam pembejaran ini.
Prevalence of sexually transmitted infections with Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium and Trichomonas vaginalis: findings from the National Survey of Sexual Lifestyles, Attitudes and Health, Slovenia, 2016 to 2017
Authors: Klavs Irena , Milavec Maja , Berlot Lina , Kustec Tanja , Grgič-Vitek Marta , Lavtar Darja , Zaletel Metka , Golle Andrej , Duh Darja , Žohar Čretnik Tjaša 
Published: April 2022

Background
To inform prevention and control of sexually transmitted infections (STIs), we need reliable prevalence estimates.

Aim
One objective of the Slovenian National Survey of Sexual Lifestyles, Attitudes and Health was to estimate the prevalence of STIs with Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium and Trichomonas vaginalis.

Methods
Data were collected between October 2016 and July 2017 in a probability sample of the general population aged 18–49 years. Computer-assisted face-to-face interviewing and self-completion of questionnaires were used. Respondents were invited to provide urine samples to be tested for STIs.

Results
Of 1,929 survey participants, 1,087 individuals provided urine samples which were tested confidentially for C. trachomatis and a subset (n = 1,023) were tested anonymously for the other STIs. The prevalence of C. trachomatis was 0.5% (95% confidence interval (CI): 0.1–1.8) in men and 1.7% (95% CI: 0.9–3.2) in women. Age-specific prevalence was the highest among individuals aged 18–24 years, 2.8% (95% CI: 0.7–10.6) in men and 4.7% (95% CI: 1.7–12.3) in women. N. gonorrhoea was not detected. Prevalence of M. genitalium was 0.5% (95% CI: 0.1–2.2) in men and 0.3% (95% CI: 0.1–1.1) in women; the highest prevalence was among men aged 25–34 years (1.1%; 95% CI: 0.2–7.5) and women aged 35–49 years (0.5%; 95% CI: 0.1–2.0). T. vaginalis was detected in the sample from one woman (0.2%; 95% CI: 0.1–1.2).

Conclusion
The substantial prevalence of C. trachomatis among young adults suggests gaps in testing, diagnosis and treatment.
HIV, STI and renal function testing frequency and STI history among current users of self-funded HIV pre-exposure prophylaxis, a cross-sectional study, Germany, 2018 and 2019
Authors: Koppe Uwe , Seifried Janna , Marcus Ulrich , Albrecht Stefan , Jansen Klaus , Jessen Heiko , Gunsenheimer-Bartmeyer Barbara , Bremer Viviane 
Published: April 2022

Introduction
Users of pre-exposure prophylaxis (PrEP) require periodic testing for HIV, sexually transmitted infections (STI) and renal function. Before PrEP was made free of charge through statutory health insurance in late 2019, PrEP users in Germany had to pay for testing themselves.

Aim
We investigated self-reported HIV, STI and renal function testing frequencies among self-funded PrEP users in Germany, factors associated with infrequent testing, and STI diagnoses.

Methods
A cross-sectional anonymous online survey in 2018 and 2019 recruited current PrEP users via dating apps for men who have sex with men (MSM), a PrEP community website, anonymous testing sites and friends. We used descriptive methods and logistic regression for analysis.

Results
We recruited 4,848 current PrEP users. Median age was 37 years (interquartile range (IQR): 30–45), 88.7% identified as male, and respectively 26.3%, 20.9% and 29.2% were tested less frequently for HIV, STI and renal function than recommended. Participants with lower STI testing frequency were significantly less likely to report STI diagnoses during PrEP use, especially among those with many partners and inconsistent condom use. Factors most strongly associated with infrequent testing included not getting tested before starting PrEP, using PrEP from informal sources and on-demand/intermittent PrEP use.

Discussion
In a setting of self-funded PrEP, many users obtained medical tests less frequently than recommended, which can lead to missed diagnoses. Barriers to testing should be addressed to enable proper medical supervision. The suitability of testing frequencies to PrEP users with less frequent risk exposures needs to be evaluated.