bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of the Need for Number of Nurses Based on Workload at the Inpatient Installation of the Sorong Regency Hospital, West Papua, during the Covid-19 Pandemic
Authors: Mirino Rudiyanto , Ratag Gustaaf A. E. , Wantania John J. 
Published: May 2022

Abstract: Provision of health services is closely related to human resources in achievement of good implementation of services especially during the covid-19 pandemic. The need for health workers in accordance with this pandemic situation is very necessary to provide qualified health services. This study aimed to analyze the need for number of nurses in terms of workload on the inpatient installations of RSUD Dr. Jhon Piet Wanane, Sorong, due to the increasing need for health services during the Covid-19 pandemic. This was a quantitative and descriptive study. Informant selection was based on the knowledge and understanding of the nurses on duty in the inpatient rooms. Calculation of the number of health personnel needs was carried out using a calculation formula which was number of cases handled multiplied by the number of treatment times then divided by the effective working time of nurses in one year. The results showed that the highest workload was in the inpatient class I and II, which was 1,065 minutes (24%), however, it was still below standard level. In conclusion, there is no high workload in RSUD Kabupaten Sorong. Hospital management could use a real formula adapted to workload situation to calculate the need for nurses and review the application model of nursing care management. Keywords: needs of human resources; health services; workload Abstrak: Pemberian pelayanan kesehatan berkaitan erat dengan penyediaan sumber daya manusia kesehatan (SDMK) agar penyelenggaraan pelayanan kesehatan dapat berjalan dengan baik terlebih pada masa pandemi Covid-19. Kebutuhan tenaga kesehatan yang memadai pada kondisi pandemi saat ini sangat diperlukan untuk memberikan pelayanan kesehatan yang berkualitas. Penelitian ini bertujuan untuk mengetahui kebutuhan jumlah tenaga perawat ditinjau dari beban kerja pada instalasi rawat inap RSUD Dr. Jhon Piet Wanane Kabupaten Sorong akibat meningkatnya kebutuhan akan pelayanan kesehatan pada masa pandemi Covid-19. Jenis penelitian ialah kuantitatif deskriptif. Informan pene-litian dipilih berdasarkan pengetahuan dan pemahaman perawat yang bertugas pada ruang rawat inap. Perhitungan jumlah kebutuhan tenaga kesehatan menggunakan rumus perhitungan banyaknya kasus yang ditangani dikalikan dengan jumlah waktu tindakan kemudian dibagi dengan waktu kerja efektif perawat dalam satu tahun. Hasil penelitian mendapatkan beban kerja tertinggi di ruang rawat inap kelas I, II yaitu 1.065 menit (24%) yang masih di bawah nilai standar. Simpulan penelitian ini ialah tidak ditemukan beban kerja yang tinggi di RSUD Kabupaten Sorong. Manajemen RSUD dapat menggunakan formula riil situasi di lapangan untuk menghitung kebutuhan tenaga perawatan di ruangan dan meninjau kembali model penerapan manajemen asuhan keperawatanKata kunci: kebutuhan sumber daya manusia kesehatan; pelayanan kesehatan; beban kerja
Treatment of Metastatic Disease with Immune Checkpoint Inhibitors Nivolumab and Pembrolizumab: Effect of Performance Status on Clinical Outcomes
Authors: Wells Leah , Cerniglia Michael , Hall Sarah , Jost Audrey C. , Britt Gregory 
Published: May 2022

ABSTRACT

Introduction
Although guidelines exist for appropriate use of chemotherapy in the metastatic setting based on performance status, such recommendations are less readily available for immune checkpoint inhibitors (ICIs). We sought to determine whether there is a relationship between Eastern Cooperative Oncology Group (ECOG) performance status and outcomes of immunotherapy in patients treated for metastatic disease at our community-based oncology practice.

Methods
Patients (n = 253) were identified as receiving nivolumab or pembrolizumab for stage IV malignancy at Cancer Centers of Colorado, St. Joseph Hospital/SCL Health between June 2018 and November 2020. Patients who initiated therapy after May 2020 were excluded from analysis due to less than 6 months follow-up time. The remaining 183 patients were included in a retrospective cohort study comparing patients with ECOG 0, 1, and 2–4. Sex, age, type of cancer, line of therapy, time on therapy and best response to therapy were determined. These baseline factors and outcomes were compared using analysis of variance (ANOVA) for numeric variables and χ2 tests of association for categorical variables. Time from initiation of ICI to death or hospice was also compared using a log-rank test as well as a multivariate Cox proportional hazards model.

Results
Of the 183 patients included, 31.7% had an ECOG of 0, 48.6% an ECOG of 1, and 19.7% an ECOG of 2–4. Non–small cell lung cancer and melanoma represented the majority of patients in each group. Sex and line of therapy did not differ between groups. There was a significant difference in age, with mean age of 62, 66, and 70 in ECOG 0, 1, and 2–4, respectively. Patients (54.6%) remained on therapy for at least 6 months, with no significant difference between groups in ability to complete 6 months of therapy. For ECOG 0, 1, and 2–4, disease control was achieved in 67.2%, 59.6%, and 41.7%, respectively. Analysis of time to death or hospice with a log-rank test showed a significant difference between groups. A multivariate Cox proportional hazards model revealed that patients with ECOG 0 had significantly longer time to death or hospice compared with patients in both other groups after controlling for age, sex, and line of therapy.

Conclusion
In this single institution retrospective study of patients receiving nivolumab or pembrolizumab for metastatic cancer, ECOG 0 was associated with disease control and increased time before death or transition to hospice.
Zileuton compression coated tablets : formulation development and in vitro evaluation
Authors: Ilapavuluri Saicharitha , Marabathuni V Jhansi Priya , Narapusetty Naidu 
Published: May 2022

In the present research work Zileuton tablets were formulated by employing compression coating technology. Initially the core tablets were prepared by using various concentrations of super disintegrates, the formulated core tablets were coated with the polymers by using compression coating technology. All the core and compress coated tablet formulations were subjected to various physical and chemical evaluation tests for core and compress coated tablets. The thickness, hardness and weight variation shown by all the tablet formulations were found within the official pharmacopoeial limits. In vitro release of Zileuton of core tablet formulations ZF5 showed faster drug release after 15 min. Faster drug release can be correlated with the high disintegration and friability observed in this study.
Substantiation of technological parameters of equipment for application of plant protection products using multicopters
Authors: Vozhik Yu. G. , Maranda S. O. , Vitrukh P. I. 
Published: May 2022

Annotation
Purpose. Improving the efficiency of field spraying and creating safe working conditions for maintenance personnel through the use of unmanned multicopters, the air jets from the propellers of which will not distort the flares of the sprayed solution of plant protection products (PPE).
Methods. The method of analysis of variable time components of agricultural units is used.
Results. Dependences of technical and operational indicators of technological equipment of a multicopter on this design and mode parameters and their rational values are received. Comparative data of multicopter and ground sprayers were obtained, which revealed the indisputable advantages of the former over the latter.
Conclusions
1.	One of the successful alternatives to ground sprayers is the use of unmanned aerial vehicles – multicopters, which, unlike ground vehicles, do not need to leave in the field among the plants technological tracks that reduce up to 5 % usable area and do not depend on soil and plant height. Due to the significant high working speed in comparison with ground means (from 3 m/s to 10 m/s) and practically absence of time for turns at the end of a run (3–5 s) one multicopter with width of capture of 10–12 m, can replace ground sprayer with a width of 50 m and five times the cost.
2.	The rational structural and functional scheme of the technological equipment of the multicopter for plant protection must be similar to the ground sprayers of the frame construction, on the sides of which the screws of the multicopter are installed, and between them the spraying equipment.
3.	Reducing the rate of application of PPE solution from low-volume (50 l/ha) to ultra-low-volume (10 l/ha) spraying increases productivity by only 1,3 times and significant complexity of the equipment.
4.	Reducing battery time during multicopter operation from 180 minutes to 10 minutes reduces performance by only 10 %.
5.	For low-volume spraying, a sufficient tank capacity for the PPE solution is 30 liters.
6.	To increase productivity and reduce material costs for batteries, the multicopter must be equipped with a hybrid power plant with an internal combustion engine, which will recharge the battery to drive its propellers.
7.	Increasing the capacity of the tank for the solution of PPE in ground sprayers from 3000 liters to 15000 liters is not economically feasible due to a slight (up to 10 %) increase in productivity, increased soil compaction and energy consumption.
Keywords: agricultural multicopter, multicopter-sprayer, agricultural drone, liquid sprayers, ultra-low-volume spraying, parameters, modes.
Guided Discovery Learning: Kreativitas Siswa pada Materi Laju Reaksi
Authors: Mayu Febby Putri 
Published: May 2022

Tujuan penelitian: Tujuan penelitian ini adalah untuk melihat pengaruh pelaksanaan model guided discovery learning terhadap kreativitas siswa di kelas XI MIA SMAN 10 Kota Jambi.
Metodologi: Penelitian ini termasuk Quasi Eksperiment dengan dengan desain one shot case study. Sampel ditentukan dengan teknik simple random sampling.Instrumen penelitian berupa lembar observasi yang terdiri dari lembar observasi keterlaksanaan model guided discovery learning dan kreativitas. Data dianalisis untuk melihat pengaruh keterlaksanaan model guided discovery learning terhadap kreativitas siswa dilakukan dengan uji regresi linier dan uji signifikansi dengan uji t.
Temuan utama: Keterlaksanaan model guided discovery learning dikategorikan baik, ditinjau dari guru dan siswa dengan rata-rata berturut- turut 95,33% dan 73,78%. Hasil uji kesamaan dua rata-rata antara data keterlaksanaan model oleh guru dan oleh siswa diperoleh thitung = 0,212 dan ttabel = 2,78. Kreativitas siswa dikategorikan baik dengan rata-rata untuk tiga kali pertemuan adalah 69,72%. Hasil uji korelasi antara keterlaksanaan model guided discovery learning oleh siswa dengan kreativitas siswa diperoleh rxy=0,766. Hasil uji hipotesis dengan uji-t diperoleh thitung= 5,58 danttabel = 2,07 dengan dk=22 dan α = 0,05.Uji hipotesis menunjukkan thitung>ttabel(5,58 > 2,07) pada taraf kepercayaan 95%. Hasil penelitian membuktikan bahwa keterlaksanaan model pembelajaran guided discovery learning berjalan dengan baik dan terdapat pengaruh antara keterlaksanaan model pembelajaran guided discovery learning dengan kreativitas siswa pada materi laju reaksi di kelas XI MIA SMAN 10 Kota Jambi
Keterbaruan penelitian: Penelitian ini memperkuat adanya pengaruh yang signifikan antara pelaksanaan model guided discovery learning dengan kreativitas siswa.
Perbedaan Kemampuan Komunikasi Matematis Siswa Dalam Model Pembelajaran Problem Based Learning Dan Model Pembelajaran Langsung Pada Materi Bangun Ruang Sisi Datar
Authors: Kiftiah Novita 
Published: May 2022

Tujuan penelitian: Penelitian ini bertujuan untuk menentukan perbedaan model pembelajaran Problem Based Learning (PBL) dengan model pembelajaran langsung terhadap kemampuan komunikasi matematis siswa pada materi bangun ruang sisi datardikelas VIII SMP Negeri 7 Muaro Jambi..
Metodologi: Jenis penelitian ini adalah penelitian kuantitatif dengan metode eksperimen. Rancangan penelitian yang digunakan adalah Post-Test Only Control Design dengan dua kelas sampel yang masingmasing diberi post-test diakhir pembelajaran. Kelas eksperimen di terapkan model pembelajaran Problem Based Learning (PBL) dan kelas kontrol diterapkan model pembelajaran langsung. Metode pengumpulan data menggunakan soal tes untuk kemampuan komunikasi tertulis, lembar observasi kemampuan komunikasi lisan siswa, dan lembar observasi keterlaksanaan pembelajaran.
Temuan utama: Dari hasil analisis data yang dilakukan menunjukkan bahwa rata-rata nilai kemampuan komunikasi matematis siswa pada kelas eksperimen yaitu 68,0631 dan rata-rata nilai kemampuan komunikasi matematis pada kelas kontrol sebesar 54,722. Hasil uji t hitung dibandingkan dengan t tabel untuk nilai kemampuan komunikasi matematis siswa didapatkan thitung > ttabel yaitu 2,641355 > 2,008559. Karena thitung berada diluar daerah penerimaan H0 sehingga H0 ditolak dan H1 diterima. Hal ini berarti rata-rata nilai kemampuan komunikasi matematis siswa yang mengikuti model pembelajaran Problem Based Learning (PBL) memiliki perbedaan dengan rata-rata nilai kemampuan komunikasi matematis siswa yang mengikuti model pembelajaran langsung.
Keterbaruan penelitian: Penelitian ini memperkuat adanya perbedaan kemampuan komunikasi matematis siswa yang mengikuti model pembelajaran problem Based learning dan model pembelajaran Langsung pada materi bangun ruang Sisi datar.
Analisis Hubungan Minat Belajar dan Hasil Belajar Materi Hukum Hooke di SMAN 10 Kota Jambi
Authors: Rahmadhani Putri 
Published: May 2022

Tujuan penelitian: Penilitian ini berfokus pada analisis hubungan minat belajar dengan hasil belajar. Tujuan dalam penilitian ini adalah untuk (1) mendeskripsikan minat belajar siswa terhadap pokok bahasan hukum hooke, (2) mendeskripsikan hasil belajar kognitif siswa pada pokok bahasan hukum hooke, dan mendeskripsikan hubungan minat belajar siswa dengan hasil belajar siswa pada pokok bahasan hukum hooke
Metodologi: Jenis penilitian ini adalah penelitian korelasional yang dilakukan di SMAN 10 Kota Jambi pada semester ganjil tahun ajaran 2020/2021. Metode pengumpulan data yang digunakan yaitu observasi dan angket
Temuan utama: Berdasarkan hasil dan pembahasan, dapat diambil kesimpulan sebagai berikut : (1) minat belajar siswa terhadap pokok bahasan hukum hooke termasuk dalam kategori cukup, dengan kata lain siswa cukup berminat untuk belajar hukum hooke, (2) hasil belajar siswa pada pokok bahasan hukum hooke termasuk dalam kategori tuntas atau memenuhi KKM yang ditetapkan sekolah, dan (3) ada hubungan yang kuat antara minat belajar dengan hasil belajar pada pokok bahasan hukum hooke di kelas XI MIPA1 dan kelas XI MIPA 3, sedangkan pada kelas XI MIPA 2 minat belajar memiliki hubungan yang rendah dengan hasil belajar.
Keterbaruan penelitian: Penelitian ini memperkuat adanya pengaruh yang signifikan antara minat dan hasil belajar siswa pada pelajaran IPA materi hukum hook.
Tantangan Anak di Indonesia Dalam Menghadapi Era Global
Authors: Mansir Firman , Kian Lia , Abas Sofyan , Sa’adi Masyhar 
Published: May 2022

This research aims to explain the threats and challenges faced by children in Indonesia. So that readiness and a strong mentality are needed to deal with them, especially in the global era. This study uses a qualitative approach, so that in collecting data through a literature study. Overall, the data are sourced from the literature and some relate to the reality that occurs in the field. The results of this study indicate that the current era of globalization has various kinds of challenges that cannot be avoided. The era of globalization with sophisticated technology poses challenges and threats that continue to grow and a child must be able to face these challenges and threats. For this reason, it is necessary to have direction and guidance that is considered capable of equipping children in the future. It is increasingly difficult to deal with children in the face of sophisticated technology so many cases are found, plus when the Covid-19 pandemic arrives like today, children are increasingly difficult to teach and guide. Thus, the problems faced by many families are children who are difficult to guide and need to be directed by instilling and teaching religious education. So that they can know about life to form an intelligent personality and become thought and pious children.
Metode Pendidikan Bhagawan Domya Sebagai Upaya Membentuk Siswa Berkarakter
Authors: Sudiani Ni Nyoman , Hemamalini Kadek , Saklit I Wayan 
Published: May 2022

This research aims to examine the educational methods applied by Bhagavan Domya in order to realize students with character. President Joko Widodo's work program outlined in Nawa Cita is to prioritize character education for the nation's generation so that character education gets more priority, namely 70 percent for elementary education level and 60 percent at the high school level, rather than the teaching and learning process for subject matter. But in reality, there is currently a deterioration in student character. The decline in student character can be allegedly because the method to educate the character of students today is not appropriate. This research is qualitative descriptive research using discourse analysis methods. The discourse analyzed is the story of Bhagavan Domya in the book Adi Parva Chapter III sloka 1 to 11 and the type of research data is written data. Discourse analysis is used to find out the educational methods hidden in the text of Bhagavan Domya's story. Data collection is done through watch and recording. The results showed that the educational period developed by Bhagavan Domya is a method of assignment, supervision, testing, appreciation and advising. The method of education proved effective in forming the character of the three students, such as the character of devotion to the teacher, hard work, responsibility, religious, tough, willing to sacrifice, caring for the environment, honesty and independent, so that the three students were given the gift of knowledge that is useful for life.
Antimicrobial Susceptibility Pattern and Virulence Genes Detection in Citrobacter freundii Isolated from Patients of a Tertiary Care Hospital, Bangladesh
Authors: Rahman Asma , Shamsuzzaman S.M. , Dola Nigha Zannat 
Published: May 2022

Background:
Citrobacter freundii is an infrequent hospital acquired pathogen to cause different types of disease in clinical settings. This pathogen is associated with wide range of infections causing unpredictably high mortality rate of 30-60%. Separation of this pathogen in health care settings is escalating and multidrug resistant strains are emerging. Therefore, this study aimed to detect antimicrobial resistance pattern and virulence genes among the isolated C. freundii.
Methods:
A total 500 samples (urine, stool, wound swab & pus, blood endotracheal aspirates and sputum) from patients with clinically suspected infections irrespective of age and sex were used in this study. Disc diffusion method was used to detect susceptibility pattern of antibiotics; colistin, tigecycline and fosfomycin susceptibility pattern was identified by minimum inhibitory concentration (MIC) method. Polymerase chain reaction (PCR) was done to detect potential virulence genes.
Results:
Among 27 isolated C. freundii, majority were resistant to amoxiclav (92.59%), trimethoprim-sulfomethoxazole (88.89%), cefotaxime and ceftazidime (85.19%) followed by ceftriaxone (81.48%), cefepime and ciprofloxacin (77.78%). MIC showed least resistance to colistin (29.63%), fosfomycin (11.11%) and tigecycline (7.41%). PCR was positive for via B gene (48.15%) and lt-A gene (25.93%). hly A, lt, lt-h genes showed negative results.
Conclusion:
Antibiotic resistance found in this study is quite worrisome as widespread resistance is seen among the bacteria isolated from human infection. Also, virulence genes play important role in C. freundii infection.
Mapping out the Stellar Populations of IC 2602 and IC 2391
Authors: Nisak Azmain H. , White Russel J. , Yep Alexandra , Henry Todd J. , Paredes Leonardo , James Hodari-Sadiki , Jao Wei-Chun 
Published: May 2022

Abstract
IC 2391 and IC 2602 are important benchmarks for testing early star and planet evolution theories, both structural and dynamical, because they are the nearest open clusters with ages of ∼50 Myr. We refine membership lists for these clusters by identifying candidate members using Gaia DR2 kinematic and distance information. We identify 451 candidate members of IC 2602 and 350 candidate members of IC 2391. If confirmed, this would increase the known populations of these clusters by 275% and 130%, respectively. We use CHIRON on the CTIO/SMARTS 1.5 m telescope via fiber mode which yields a resolution of 27,400 to acquire high-resolution spectra of 26 new candidate cluster members brighter than G = 13 magnitude, as well as an additional 12 previously known members. Measures of lithium, Hα, stellar properties (T
eff, log(g), [Fe/H]), radial velocities, and

v
sin
i

values from these spectra are used to confirm cluster membership. We find that 37 of 38 stars we observe are bona fide cluster members, of which four are new candidate photometric binaries and 10 are new candidate spectroscopic binaries.
Physical Properties of the Supernova Remnant Population in the Small Magellanic Cloud
Authors: Leahy D. A. , Filipović M. D. 
Published: May 2022

Abstract
The X-ray emission from a supernova remnant is a powerful diagnostic of the state of its shocked plasma. The temperature and the emission measure are related to the energy of the explosion, the age of the remnant, and the density of the surrounding medium. Here we present the results of a study of the remnant population of the Small Magellanic Cloud. Progress in X-ray observations of remnants has resulted in a sample of 20 remnants in the Small Magellanic Cloud with measured temperatures and emission measures. We apply spherically symmetric supernova remnant evolution models to this set of remnants to estimate ages, explosion energies, and circumstellar medium densities. The distribution of ages yields a remnant birth rate of ∼1/1200 yr. The energies and densities are well fit with log-normal distributions, with means of 1.6 × 1051 erg and 0.14 cm−3, and 1σ dispersions of a factor of 1.87 in energy and 3.06 in density, respectively.
The Redshift Evolution of the Binary Black Hole Merger Rate: A Weighty Matter
Authors: van Son L. A. C. , de Mink S. E. , Callister T. , Justham S. , Renzo M. , Wagg T. , Broekgaarden F. S. , Kummer F. , Pakmor R. , Mandel I. 
Published: May 2022

Abstract
Gravitational-wave detectors are starting to reveal the redshift evolution of the binary black hole (BBH) merger rate, R
BBH(z). We make predictions for R
BBH(z) as a function of black hole mass for systems originating from isolated binaries. To this end, we investigate correlations between the delay time and black hole mass by means of the suite of binary population synthesis simulations, COMPAS. We distinguish two channels: the common envelope (CE), and the stable Roche-lobe overflow (RLOF) channel, characterized by whether the system has experienced a common envelope or not. We find that the CE channel preferentially produces BHs with masses below about 30 M
⊙ and short delay times (t
delay ≲ 1 Gyr), while the stable RLOF channel primarily forms systems with BH masses above 30 M
⊙ and long delay times (t
delay ≳ 1 Gyr). We provide a new fit for the metallicity-dependent specific star formation rate density based on the Illustris TNG simulations, and use this to convert the delay time distributions into a prediction of R
BBH(z). This leads to a distinct redshift evolution of R
BBH(z) for high and low primary BH masses. We furthermore find that, at high redshift, R
BBH(z) is dominated by the CE channel, while at low redshift, it contains a large contribution (∼40%) from the stable RLOF channel. Our results predict that, for increasing redshifts, BBHs with component masses above 30 M
⊙ will become increasingly scarce relative to less massive BBH systems. Evidence of this distinct evolution of R
BBH(z) for different BH masses can be tested with future detectors.