bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modelling Surround‐aware Contrast Sensitivity for HDR Displays
Authors: Yi Shinyoung , Jeon Daniel S. , Serrano Ana , Jeong Se‐Yoon , Kim Hui‐Yong , Gutierrez Diego , Kim Min H. 
Published: January 2022

AbstractDespite advances in display technology, many existing applications rely on psychophysical datasets of human perception gathered using older, sometimes outdated displays. As a result, there exists the underlying assumption that such measurements can be carried over to the new viewing conditions of more modern technology. We have conducted a series of psychophysical experiments to explore contrast sensitivity using a state‐of‐the‐art HDR display, taking into account not only the spatial frequency and luminance of the stimuli but also their surrounding luminance levels. From our data, we have derived a novel surround‐aware contrast sensitivity function (CSF), which predicts human contrast sensitivity more accurately. We additionally provide a practical version that retains the benefits of our full model, while enabling easy backward compatibility and consistently producing good results across many existing applications that make use of CSF models. We show examples of effective HDR video compression using a transfer function derived from our CSF, tone‐mapping and improved accuracy in visual difference prediction.
Fetal case of rare association of hypoplastic left heart syndrome and absent atrial septum accompanied by mixed form of supracardiac total anomalous pulmonary venous connection
Authors: Maruyama Wakako , Kawasaki Yuki , Murakami Yosuke , Fujino Mitsuhiro , Sasaki Takeshi , Nakamura Kae , Ehara Eiji 
Published: January 2022

AbstractAbnormal pulmonary venous flow patterns on fetal echocardiography and a nutmeg lung pattern on fetal magnetic resonance imaging are seen in patients with pulmonary venous stenosis. The association between these findings and the degree of pulmonary venous stenosis remains unknown. We report an extremely rare case of a fetus diagnosed with hypoplastic left heart syndrome complicated by an absent atrial septum and supracardiac total anomalous pulmonary venous connection with left pulmonary venous congestion. This case suggests that compared to non‐pulsatile continuous pulmonary venous flow, the nutmeg lung pattern can only be observed with severe pulmonary congestion and advanced pulmonary lymphangiectasia.
Odontoma malformation and disturbances of eruption subsequent to traumatic dental injuries: A literature review and a case report
Authors: Silva Daniela R. , Shahinian Anna L. 
Published: January 2022

AbstractDue to the close proximity of the primary teeth with the developing permanent successors, several developmental alterations in the permanent successors have been reported as consequences of traumatic dental injuries to the primary dentition. When they occur at a very young age such trauma could disturb normal tooth development and cause rare anomalies, including sequestration of the permanent tooth germ and odontoma‐like malformations. A literature review of case reports with a history of trauma and odontoma formation is discussed in this paper. This paper also includes a case report of a patient, who was 3‐years and 5‐months old, when she was seen at the University of California, Los Angeles Children's Dental Center for the first time. The grandmother reported that the child was dropped from the father's lap when she was 2 weeks old and suffered head trauma and multiple skull fractures.
Rethinking age heaping again for understanding its possibilities and limitations
Authors: Baten Joerg , Benati Giacomo , Ferber Sarah 
Published: January 2022

AbstractA'Hearn, Delfino, and Nuvolari recently argued in this journal that the indicator function of age heaping for education, and numeracy in particular, is quite limited. In contrast, we show empirically that by applying the methodological elements that were developed over the past decade, age‐heaping‐based numeracy research can be an important tool for economic history.
Disturbed expression of vitamin D and retinoic acid‐related orphan receptors α and γ and of megalin in inflammatory skin diseases
Authors: Brożyna Anna A. , Żmijewski Michał A. , Linowiecka Kinga , Kim Tae‐Kang , Slominski Radomir M. , Slominski Andrzej T. 
Published: January 2022

AbstractThe pathogenesis of inflammatory skin diseases is associated with the abnormal activity of keratinocytes and immune cells infiltrate. Vitamin D3 deficiency can correlate with the increased incidence, severity and duration of inflammatory skin disorders. The exact mechanism on how vitamin D3 influences inflammatory skin diseases still requires clarification. However, it can be associated with the disturbances in transmembrane glycoprotein—LRP2/megalin, which is implicated in vitamin D3 transport to the cell, and defects in vitamin D‐signalling through the nuclear receptors. Therefore, by using immunohistochemistry, we analysed the expression of LRP2/megalin, VDR, RORα and RORγ in allergic contact dermatitis, lichen simplex chronicus, sarcoidosis and psoriasis in comparison with the normal skin. We observed decreased expression of LRP2/megalin in all inflammatory lesions in comparison with the normal skin. Significant differences were also noticed in VDR, RORα and RORγ levels between inflammatory lesions and normal skin. Our research indicates disturbed expression of LRP2/megalin, VDR, RORα and RORγ in inflammatory skin lesions in comparison with normal skin. Therefore, we suggest that changes in the activity of these proteins may play role in pathogenesis of inflammatory skin disorders. Furthermore, we suggest that LRP2/megalin, VDR, RORα and RORy may serve as targets in therapy of these diseases.
The private sector and multidimensional poverty reduction in Vietnam: A cross‐province panel data analysis
Authors: Van Le Dao , Tran Tuyen Quang , Doan Tinh 
Published: January 2022

AbstractThis study examines the role of private sector development (PSD) in multidimensional poverty alleviation in Vietnam, using provincial panel data for the 2010–2019 period. PSD is measured as the proportion of the workforce in (i) all private firms, (ii) domestic private firms, and (iii) multinational firms, respectively. We use a two‐step general method of moment estimator to account for unobservable heterogeneity, simultaneity, and the relationship between current provincial characteristics and past provincial poverty. We find that each percentage point increase in private sector employment contributes to a reduction of 0.30% and 0.31% in multidimensional poverty and monetary poverty, respectively. Notably, further analysis confirms that a similar effect is also found for both domestic private and multinational enterprises. In addition, our study finds that economic growth and educational attainment emerge as major factors mitigating multidimensional and unidimensional poverty, while income inequality increases both poverty measures.
Local orders, lattice distortions, and electronic structure dominated mechanical properties of (ZrHfTaM1M2)C (M = Nb, Ti, V)
Authors: Yao Gang , Wang William Yi , Zou Chengxiong , Ren Ke , Li Peixuan , Gao Xingyu , Lin Deye , Wang Jun , Yang Shufeng , Wang Yiguang , Song Haifeng , Li Jinshan 
Published: January 2022

AbstractHigh‐entropy carbides (HECs) are regarded as potential candidate structural materials with attractive mechanical properties due to their ultra‐high hardness. It is essential to reveal the atomic and electronic basis for strengthening mechanism in order to develop the advanced HECs. In the present work, C (M = Nb, Ti, V) are selected as case studies. The effects of transition metals (M) on the lattice parameters, bulk modulus, enthalpy of formation, electron work function (EWF), and bonding morphology/strength of HECs are comprehensively studied by first‐principles calculations. It is found that the lattice parameters, equilibrium volumes, and bulk modulus of HECs are improved with the increase of M atomic volumes. The atomic‐size differences among various groups of elements not only result in the lattice mismatch/distortion but also contribute to the formation of weak spots. In the view of bonding charge density, the electron redistributions caused by the coupling effect of the lattice distortion and valance electron differences can be revealed obviously, which identify the different bonding strength. Moreover, in terms of EWF, the proposed power‐law‐scaled hardness of HECs is validated and matches well with those reported theoretical and experimental results, providing a strategy to design advanced HECs with excellent mechanical properties.
Enhancing the biodesulphurization capacity of Rhodococcus sp. FUM94 in a biphasic system through optimization of operational factors
Authors: Hokmabadi Mahsa , Khosravinia Somayeh , Mahdavi Mahmood A. , Gheshlaghi Reza 
Published: January 2022

Abstract
The biodesulfurization activity of bacteria through the 4S pathway in aqueous-oil emulsions is affected by various operational factors. These factors also demonstrate interacting effects that influence the potential for field applications of biodesulfurization technology and can solely be deciphered through multi-variable experiments. In this study, the effects of the influential factors and their interactions on the desulfurizing activity of a newly identified desulfurizing bacterium, Rhodococcus sp, FUM94 were quantitatively investigated. The capacity improvement achieved through optimized values obtained in this study is significant due to its simple implementation to large scale processes. This is the most simple and the most cost-effective way to scale-up a biodesulfurization process.Using response surface methodology (RSM). Optimum values of the factors were identified with the objective of maximizing biodesulfurization activity. Results revealed that the desulfurization activity of the biocatalyst increased from 0.323 ± 0.072 to 46.57 ± 4.556 mmol 2-Hydroxybiphenyl (kg dry cell weight)−1h−1 at the optimized conditions of 6 h reaction time, 2 g.L−1 biocatalyst concentration, 0.54 mM (100 ppm) dibenzothiophene (DBT) concentration (sulfur source), and 25% oil phase fraction. Desirability analysis proved that the selected conditions are the most desirable combination of factors (desirability value = 0.896) to achieve the highest biodesulfurization activity of the biocatalyst. A comparison between the biodesulfurization capacity achieved in this study and the capacities reported in similar studies published in the past two decades revealed that biodesulfurization under optimized operational conditions outperforms previously proposed techniques.
Structure and functional capacity of a benzene-mineralizing, nitrate-reducing microbial community
Authors: Eziuzor Samuel C. , Corrêa Felipe B. , Peng Shuchan , Schultz Júnia , Kleinsteuber Sabine , da Rocha Ulisses N. , Adrian Lorenz , Vogt Carsten 
Published: January 2022

AbstractAimsHow benzene is metabolized by microbes under anoxic conditions is not fully understood. Here, we studied the degradation pathways in a benzene-mineralizing, nitrate-reducing enrichment culture.Methods and resultsBenzene mineralization was dependent on the presence of nitrate and correlated to the enrichment of a Peptococcaceae phylotype only distantly related to known anaerobic benzene degraders of this family. Its relative abundance decreased after benzene mineralization had terminated, while other abundant taxa—Ignavibacteriaceae, Rhodanobacteraceae and Brocadiaceae—slightly increased. Generally, the microbial community remained diverse despite the amendment of benzene as single organic carbon source, suggesting complex trophic interactions between different functional groups. A subunit of the putative anaerobic benzene carboxylase previously detected in Peptococcaceae was identified by metaproteomic analysis suggesting that benzene was activated by carboxylation. Detection of proteins involved in anaerobic ammonium oxidation (anammox) indicates that benzene mineralization was accompanied by anammox, facilitated by nitrite accumulation and the presence of ammonium in the growth medium.ConclusionsThe results suggest that benzene was activated by carboxylation and further assimilated by a novel Peptococcaceae phylotype.Significance and impact of the studyThe results confirm the hypothesis that Peptococcaceae are important anaerobic benzene degraders.
Broussonin A– and B–mediated inhibition of angiogenesis by blockade of VEGFR‐2 signalling pathways and integrin β1 expression
Authors: Kim Jae Hyeon , Kim Sunho , Han Surim , Ahn Eun‐Kyung , Cho Young‐Rak , Jeong Wonsik , Kim Sung Joon , Bae Gyu‐Un , Oh Joa Sub , Seo Dong‐Wan 
Published: January 2022

AbstractIn the present study, we demonstrate the regulatory effects and mechanism of broussonin A and B, diphenylpropane derivatives isolated from Broussonetia kazinoki, on vascular endothelial growth factor‐A (VEGF‐A)–stimulated endothelial cell responses in vitro and microvessel sprouting ex vivo. Treatment with broussonin A or B suppressed VEGF‐A‐stimulated endothelial cell proliferation by regulating the expression of cell cycle–related proteins and the phosphorylation status of retinoblastoma protein. In addition, treatment with broussonin A or B abrogated VEGF‐A‐stimulated angiogenic responses including endothelial cell migration, invasion, tube formation and microvessel formation from rat aortic rings. These anti‐angiogenic activities of broussonin A and B were mediated through inactivation of VEGF‐A‐stimulated downstream signalling pathways, localization of vascular endothelial‐cadherin at cell‐cell contacts, and down‐regulation of integrin β1 and integrin‐liked kinase. Furthermore, treatment with broussonin A or B inhibited proliferation and invasion of non–small cell lung cancer and ovarian cancer cells. Taken together, our findings suggest the pharmacological potential of broussonin A and B in the regulation of angiogenesis, cancer cell growth and progression.
Cold storage of Spodoptera litura eggs and Telenomus remus adults for improving mass‐rearing efficiency
Authors: Chen Wanbin , Zhang Hongzhi , Jing Xiaoyu , Li Yuyan , Wang Mengqing , Mao Jianjun , Weng Qingfen , Nie Rui , Zhang Lisheng 
Published: January 2022

AbstractTelenomus remus (Nixon) has shown promising potential as a biological control agent for the major invasive agricultural pest, Spodoptera frugiperda (J. E. Smith). Application of biological control programmes in the field requires an efficient mass‐rearing system to provide sufficient numbers of beneficial insects. The short longevity of parasitoid adults and limited period of availability of host eggs are two factors affecting the mass‐rearing efficiency of T. remus. Using Spodoptera litura (Fabricius) eggs as an alternative host, the effects of cold storage of S. litura eggs and T. remus adults at 5°C, 8°C and 11°C for different time durations on the fitness of the parasitoid were investigated to identify the most suitable storage conditions. Results showed that T. remus can successfully exploit stored S. litura eggs, but the number of parasitized eggs decreased with increased egg storage duration and/or reduced storage temperature. For refrigerated adults, the survival rate declined gradually with longer storage duration, and the females' survival rate was higher than the males' at any treatment. Similarly, parasitism capacity of stored adults declined significantly with prolonged storage. Female adult longevity was significantly shorter than the control for all treatments. However, the offspring emergence rate and percentage of females were barely affected by cold storage. In conclusion, S. litura eggs can be stored at 11°C for up to 9 days and adult T. remus can be stored at 8°C or 11°C for up to 7 days without significant losses. Data obtained from this study will help coordinate different aspects of T. remus production, decreasing costs and improving the biocontrol materials' availability.
Transient computer simulation of the temperature profile in different packaging materials: An optimization of thermal treatment of tender coconut water
Authors: Prithviraj V. , Pandiselvam Ravi , Manikantan M. R. , Ramesh S. V. , Shameena Beegum P. P. , Kothakota Anjineyulu , Mousavi Khaneghah Amin 
Published: January 2022

AbstractUnderstanding the temperature profile of different packaging materials would be useful for selecting appropriate packaging material for in‐bottle pasteurization. The temperature profile of polypropylene, polyethylene (PE), and polyethylene terephthalate bottles was investigated using COMSOL Multiphysics software to understand the temperature–time correlation with thermal treatments. PE bottles exhibited the least temperature difference between cold and hot spots. Optimization of thermal treatment processing parameters such as temperature (80–95°C) and treatment time (5–15 min) for inactivation of enzymes, namely polyphenol oxidase (PPO) and peroxidase (POD), in tender coconut water (TCW) was performed to the extent its shelf life. The quality parameters of heat‐treated TCW such as pH, total soluble solids (TSS), titratable acidity (TA), turbidity, phenolic content, PPO, POD, and sensory evaluation were analyzed. The multiple linear regression models were developed for each quality parameter using a central composite design (CCD). The optimized treatment conditions were 84°C temperature and 5 min treatment time with the desirability of 0.926. The responses recorded were pH = 5.4, TSS = 5.52, turbidity = 7.1 NTU, TA = 0.06% of malic acid, relative PPO = 0.099, relative POD = 0.093, phenolic content = 44.712 mg gallic acid equivalent/L, and overall acceptability score = 8.Practical ApplicationsUnderstanding the temperature profile of different packaging materials during pasteurization or sterilization is imperative to select the suitable packaging material, and also it would be helpful for designing the heating system. Tender coconut water (TCW) is the most popular natural drink in Asian countries. However, the pasteurization conditions are yet to be optimized to preserve TCW without affecting its bioactive and functional components. The current practice followed for in‐bottle sterilization of TCW is polyethylene terephthalate (PET). This is due to PET being cheaper and readily available than other packaging materials. However, the quality of the TCW could affect PET due to improper heat distribution which can lead to damage of bioactive components. The present study has optimized the suitable pasteurization conditions and packaging material for bottling and marketing TCW. The findings of the present study will boost the market potential of the tender coconut processing industries.
The relationship between the reminiscence of relationship‐defining memories and marital outcomes: A systematic review and meta‐analysis
Authors: Majzoobi Mohammad Reza , Forstmeier Simon 
Published: January 2022

AbstractThe current systematic review aimed to explore the interdependence of relationship‐defining memories (RDMs) with positive and negative marital outcomes in order to gain a deeper insight into the nature, content, and the reminiscence of RDMs, as well as the role they may serve in the marital relationship. The studies included in the current systematic review had addressed RDMs and their impact on marital outcomes among healthy people above the age of 18 who are in a romantic relationship. After checking the studies found in our search through the scientific databases against the eligibility criteria, 16 studies were included in the systematic review, of which 14 were found to be eligible for a meta‐analysis. The results of the meta‐analysis indicated a relatively moderate and high correlation of RDMs with marital outcomes (r = .334) and marital satisfaction (r = .445), respectively. The review of included studies revealed that there is an inextricable link between RDMs and significant marital outcomes such as marital satisfaction, intimacy, well‐being, quality, and suchlike.
Northern gene flow into southeastern East Asians inferred from genome‐wide array genotyping
Authors: He Guang‐Lin , Li Ying‐Xiang , Zou Xing , Yeh Hui‐Yuan , Tang Ren‐Kuan , Wang Pei‐Xin , Bai Jing‐Ya , Yang Xiao‐Min , Wang Zheng , Guo Jian‐Xin , Chen Jin‐Wen , Chen Jing , Yang Mei‐Qing , Zhao Jing , Sun Jin , Zhu Kong‐Yang , Ma Hao , Wang Rui , Yang Wen‐Jiao , Hu Rong , Wei Lan‐Hai , Hou Yi‐Ping , Wang Meng‐Ge , Chen Gang , Wang Chuan‐Chao 
Published: January 2022

AbstractThe population history of Southeast (SE) China remains poorly understood due to the sparse sampling of present‐day populations and limited modeling with ancient genomic data. We report genome‐wide genotyping data from 207 present‐day Han Chinese and Hmong‐Mien (HM)‐speaking She people from Fujian and Taiwan Island, SE China. We coanalyzed 66 Early Neolithic to Iron Age ancient Fujian and Taiwan Island individuals obtained from previously published works to explore the genetic continuity and admixture based on patterns of genetic variations of the high‐resolution time transect. We found the genetic differentiation between northern and southern East Asians was defined by a north–south East Asian genetic cline and our studied southern East Asians were clustered in the southern end of this cline. The southeastern coastal modern East Asians are genetically similar to other southern indigenous groups as well as geographically close to Neolithic‐to‐Iron Age populations, but they also shared excess alleles with post‐Neolithic Yellow River ancients, which suggested a southward gene flow on the modern southern coastal gene pool. In addition, we identified one new HM genetic cline in East Asia with the coastal Fujian HM‐speaking She localizing at the intersection between HM and Han clines. She people show stronger genetic affinity with southern East Asian indigenous populations, with the main ancestry deriving from groups related to southeastern ancient indigenous rice farmers. The southeastern Han Chinese could be modeled with the primary ancestry deriving from the group related to the Yellow River Basin millet farmers and the remaining from groups related to rice farmers, which was consistent with the northern China origin of modern southeastern Han Chinese and in line with the historically and archaeologically attested southward migrations of Han people and their ancestors. Our estimated north–south admixture time ranges based on the decay of the linkage disequilibrium spanned from the Bronze Age to historic periods, suggesting the recent large‐scale population migrations and subsequent admixture participated in the formation of modern Han in SE Asia.
Ent-hardwickiic acid from C. pubiflora and its microbial metabolites are more potent than fluconazole in vitro against Candida glabrata
Authors: Sousa Teixeira M.V. , Fernandes L.M. , Stefanelli de Paula V. , Ferreira A.G. , Jacometti Cardoso Furtado N.A. 
Published: January 2022

Abstract
The incidence of Candida glabrata infections has rapidly grown and this species is among those responsible for causing invasive candidiasis with a high mortality rate. The diterpene ent-hardwickiic acid is a major constituent in Copaifera pubiflora oleoresin and the ethnopharmacological uses of this oleoresin by people from Brazilian Amazonian region point to a potential use of this major constituent as an antimicrobial. Therefore, the goal of this study was to evaluate the antifungal activity of ent-hardwickiic acid against Candida species and to produce derivatives of this diterpene by using microbial models for simulating the mammalian metabolism. The microbial transformations of ent-hardwickiic acid were carried out by Aspergillus brasiliensis and Cunninghamella elegans and hydroxylated metabolites were isolated and their chemical structures were determined. The antifungal activity of ent-hardwickiic acid and its metabolites was assessed by using the microdilution broth method in 96-well microplates and compared with that of fluconazole. All the diterpenes showed fungistatic effects (ranging from 19·7 to 75·2 µmol l−1) against C. glabrata at lower concentrations than fluconazole (163·2 µmol l−1) and were more potent fungicides (ranging from 39·5 to 150·4 µmol l−1) than fluconazole, which showed fungicidal effect at the concentration of 326·5 µmol l−1.