bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predicting at-risk opioid use three months after ed visit for trauma: Results from the AURORA study
Authors: Punches Brittany E. , Stolz Uwe , Freiermuth Caroline E. , Ancona Rachel M. , McLean Samuel A. , House Stacey L. , Beaudoin Francesca L. , An Xinming , Stevens Jennifer S. , Zeng Donglin , Neylan Thomas C. , Clifford Gari D. , Jovanovic Tanja , Linnstaedt Sarah D. , Germine Laura T. , Bollen Kenneth A. , Rauch Scott L. , Haran John P. , Storrow Alan B. , Lewandowski Christopher , Musey Paul I. , Hendry Phyllis L. , Sheikh Sophia , Jones Christopher W. , Kurz Michael C. , Gentile Nina T. , McGrath Meghan E. , Hudak Lauren A. , Pascual Jose L. , Seamon Mark J. , Harris Erica , Chang Anna M. , Pearson Claire , Peak David A. , Merchant Roland C. , Domeier Robert M. , Rathlev Niels K. , O’Neil Brian J. , Sanchez Leon D. , Bruce Steven E. , Pietrzak Robert H. , Joormann Jutta , Barch Deanna M. , Pizzagalli Diego A. , Smoller Jordan W. , Luna Beatriz , Harte Steven E. , Elliott James M. , Kessler Ronald C. , Ressler Kerry J. , Koenen Karestan C. , Lyons Michael S. 
Published: September 2022

ObjectiveWhether short-term, low-potency opioid prescriptions for acute pain lead to future at-risk opioid use remains controversial and inadequately characterized. Our objective was to measure the association between emergency department (ED) opioid analgesic exposure after a physical, trauma-related event and subsequent opioid use. We hypothesized ED opioid analgesic exposure is associated with subsequent at-risk opioid use.MethodsParticipants were enrolled in AURORA, a prospective cohort study of adult patients in 29 U.S., urban EDs receiving care for a traumatic event. Exclusion criteria were hospital admission, persons reporting any non-medical opioid use (e.g., opioids without prescription or taking more than prescribed for euphoria) in the 30 days before enrollment, and missing or incomplete data regarding opioid exposure or pain. We used multivariable logistic regression to assess the relationship between ED opioid exposure and at-risk opioid use, defined as any self-reported non-medical opioid use after initial ED encounter or prescription opioid use at 3-months.ResultsOf 1441 subjects completing 3-month follow-up, 872 participants were included for analysis. At-risk opioid use occurred within 3 months in 33/620 (5.3%, CI: 3.7,7.4) participants without ED opioid analgesic exposure; 4/16 (25.0%, CI: 8.3, 52.6) with ED opioid prescription only; 17/146 (11.6%, CI: 7.1, 18.3) with ED opioid administration only; 12/90 (13.3%, CI: 7.4, 22.5) with both. Controlling for clinical factors, adjusted odds ratios (aORs) for at-risk opioid use after ED opioid exposure were: ED prescription only: 4.9 (95% CI 1.4, 17.4); ED administration for analgesia only: 2.0 (CI 1.0, 3.8); both: 2.8 (CI 1.2, 6.5).ConclusionsED opioids were associated with subsequent at-risk opioid use within three months in a geographically diverse cohort of adult trauma patients. This supports need for prospective studies focused on the long-term consequences of ED opioid analgesic exposure to estimate individual risk and guide therapeutic decision-making.
Muscle contractile exercise through a belt electrode device prevents myofiber atrophy, muscle contracture, and muscular pain in immobilized rat gastrocnemius muscle
Authors: Honda Yuichiro , Takahashi Ayumi , Tanaka Natsumi , Kajiwara Yasuhiro , Sasaki Ryo , Okita Seima , Sakamoto Junya , Okita Minoru 
Published: September 2022

Purpose
Immobilization of skeletal muscles causes muscle atrophy, muscle contracture, and muscle pain, the mechanisms of which are related to macrophage accumulation. However, muscle contractile exercise through a belt electrode device may mitigate macrophage accumulation. We hypothesized that such exercise would be effective in preventing myofiber atrophy, muscle contracture, and muscular pain. This study tested this hypothesis in immobilized rat gastrocnemius muscle.

Materials and methods
A total of 32 rats were divided into the following control and experimental groups: immobilization (immobilized treatment only), low-frequency (LF; immobilized treatment and muscle contractile exercise with a 2 s (do) /6 s (rest) duty cycle), and high-frequency (HF; immobilized treatment and muscle contractile exercise with a 2 s (do)/2 s (rest) duty cycle). Electrical stimulation was performed at 50 Hz and 4.7 mA, and muscle contractile exercise was applied to the lower limb muscles for 15 or 20 min/session (once daily) for 2 weeks (6 times/week). After the behavioral tests, the bilateral gastrocnemius muscles were collected for analysis.

Results
The number of macrophages, the Atrogin-1 and MuRF-1 mRNA expression, and the hydroxyproline content in the HF group were lower than those in the immobilization and LF groups. The cross-sectional area (CSA) of type IIb myofibers in the superficial region, the PGC-1α mRNA expression, and the range of motion of dorsiflexion in the HF group were significantly higher than those in the immobilization and LF groups. The pressure pain thresholds in the LF and HF groups were significantly higher than that in the immobilization group, and the nerve growth factor (NGF) content in the LF and HF groups was significantly lower than that in the immobilization group.

Conclusion
Muscle contractile exercise through the belt electrode device may be effective in preventing immobilization-induced myofiber atrophy, muscle contracture, and muscular pain in the immobilized rat gastrocnemius muscle.
EXPORT OF ALTAI PRODUCTS AS A COMPONENT OF THE REGION'S IMAGE
Authors: Butakova M. M. , Sokolova O. N. 
Published: September 2022

The article is devoted to assessing and identifying the problems of mutual influence of export activities and the image of the region, manifested through the influence of the image of the region on the prospects for the development of export activities and export activities on the image of the region. The relevance of the problem is connected with the need to strengthen the export positions of the Altai Territory in order to ensure the growth of its image in foreign markets. The authors have studied and evaluated the dynamics and structure of exports as a factor that has a significant impact on the image of the Altai Territory, identified possible areas of activity to improve its image in foreign markets, which, in turn, can positively affect the intensification of export activities.
The growth of exports of Altai Krai products to foreign markets, the increase in its competitiveness, as well as the constantly changing market conditions update the study of the components of the image of the exporting region, require monitoring of the factors that determine it, taking into account the changing preferences of importers.
As a result of theoretical studies of the problems of the image of the region, export activity, supported by analytical calculations of the dynamics and structure of exports of the main commodity groups of products of the Altai Territory in 2016-2020, the authors came to the conclusion that exports on the image of the region and the image on the prospects for the development of exports, the need to search ways to improve the effectiveness of mutual influence, based on the unique characteristics of the region.
THE CONCEPT AND APPROACHES TO THE STUDY OF INTEGRATION OF TERRITORIAL SOCIO-ECONOMIC SYSTEMS: TO THE FORMULATION OF THE ISSUE
Authors: Trotskovsky A. Ya. , Kaplinskaya I. Ye. , Rodionova L. V. 
Published: September 2022

The importance of the development of the Russian economy as a comprehensive and sovereign system is increasing under the influence of external shocks. To this matter, the question of the economy’s spatial nature in regards to the deepening of integration processes between regions becomes particularly important.
The purpose of the study is to develop theoretical and methodological foundations for analyzing the mechanisms of integrating the economies of the regions of the Siberian Federal District, assessing the integration potential of the Altai Krai. The empirical object of study is the Altai Krai. The subject of the study are the various forms and types of connections between the region and the regions of the Siberian Federal District.
The paper considers a number of topical issues of interregional integration. A general assessment of the state of scientific research in this area is given. Insufficient empirical knowledge of interregional relations, the absence of comparable methodological approaches to the assessment of integration processes in macroregions are noted.
The possibility of using methodological developments in the field of international integration research for the analysis of interregional interaction is substantiated and shown. Approaches to assessing the degree of «maturity» of interregional integration are outlined.
The «mechanism» of integration is revealed as the unity of the driving forces of this process and the factors that determine it, in relation to different types of interregional relations.
The ambiguity of the consequences of integration for the socio-economic development of regions is shown, depending on the basis on which interregional relations are formed (cooperation or competition).
Linear barycentric rational collocation method for solving biharmonic equation
Authors: Li Jin 
Published: September 2022

AbstractTwo-dimensional biharmonic boundary-value problems are considered by the linear barycentric rational collocation method, and the unknown function is approximated by the barycentric rational polynomial. With the help of matrix form, the linear equations of the discrete biharmonic equation are changed into a matrix equation. From the convergence rate of barycentric rational polynomial, we present the convergence rate of linear barycentric rational collocation method for biharmonic equation. Finally, several numerical examples are provided to validate the theoretical analysis.
Fully degenerate Bernoulli numbers and polynomials
Authors: Kim Taekyun , Kim Dae San , Park Jin-Woo 
Published: September 2022

Abstract
The aim of this article is to study the fully degenerate Bernoulli polynomials and numbers, which are a degenerate version of Bernoulli polynomials and numbers and arise naturally from the Volkenborn integral of the degenerate exponential functions on

Z

p

{{\mathbb{Z}}}_{p}

. We find some explicit expressions for the fully degenerate Bernoulli polynomials and numbers in terms of the degenerate Stirling numbers of the second kind, the degenerate

r

r

-Stirling numbers of the second kind, and the degenerate Stirling polynomials. We also consider the degenerate poly-Bernoulli polynomials and derive explicit representations for them in terms of the same degenerate Stirling numbers and polynomials.
Humor and resilience: relationships with happiness in young adults
Authors: Kennison Shelia M. 
Published: September 2022

Abstract
Prior research has shown that more resilient individuals report higher levels of happiness. Other research also shows that those who use positive humor styles (i.e., self-enhancing and affiliative) more often and use negative humor styles (i.e., aggressive and self-defeating) less often report higher levels of happiness. Resilience research has characterized resilience as involving multiple protective factors that contribute to functioning better than expected despite past or present adversities. The present research tested the hypothesis that the use of one or more humor styles may function as distinct protective factors of resilience in predicting happiness. An online survey study with a sample of 204 (105 men, 99 women) young adults showed that after controlling for resilience, less frequent use of the negative humor styles (i.e., aggressive and self-defeating) emerged as protective factors, related to higher levels of happiness. The use of the positive humor styles did not account for additional variance in happiness after resilience was controlled. The results are compatible with research suggesting that improvements in well-being are associated with behavioral changes.
Frequency responses for induced neural transmembrane potential by electromagnetic waves (1 kHz to 1 GHz)
Authors: Bakhtiary Zahra Hajizadeh , Saviz Mehrdad 
Published: September 2022

Abstract
Many biophysical effects of electromagnetic radiation are interpreted based on the induced voltage on cellular membranes. It is very instructive to study wideband frequency responses showing how an impinging electromagnetic wave carrying a certain time waveform translates into a time-dependent change in the cell-membrane potentials in any desired tissue. A direct numerical solution of this problem with realistic models for the body and cells results in meshcells of nanometer dimensions, which is unaffordable for almost any computing machine. In this paper, we exploit a multiscale method with serial frequency responses to arrive at the final frequency response for the induced transmembrane potential changes in cerebral cells induced by electromagnetic waves incident on the body. The results show a bandpass characteristic; a frequency window of approximately 10 kHz to 100 MHz as the most sensitive frequency band for neuronal membrane sensing of external electromagnetic fields.
Conventional/linear/Lorentzian material gain semiconductor optical amplifiers performance signature with four wave mixing (FWM) nonlinearity in optical fiber communication systems
Authors: Smirani Lassaad K. , Rashed Ahmed Nabih Zaki , Ahammad S. K. Hasane , Hossain Md. Amzad , Daher Malek G. , Fahmy Eslam 
Published: September 2022

Abstract
This study demonstrates the FWM nonlinearity effects on fiber systems based on conventional/linear/Lorentzian material gain wide band traveling wave semiconductor optical amplifiers (WBTWSOAs) at data rates of 10 Gbps. Max signal power (MSP) and noise power (NP) levels are illustrated versus time and SW after WDM multiplexer. The MSP and min NP are clarified against time and SW based conventional, linear, Lorentzian material gain WBTWSOAs. The total optical power after WDM multiplexer, and the total optical power based conventional, linear, Lorentzian material gain WBTWSOAs are measured. Max Q versus time after receiver based WDM multiplexer, and max Q versus time after receiver based conventional, linear, Lorentzian material gain WBTWSOAs are reported clearly in this study. Besides the max Q against CS is studied with/without FWM effects. Nonlinear coefficient, conversion efficiency is analyzed clearly against fiber length without/with FWM effects.
IUGS–IUPAC recommendations and status reports on the half-lives of 87Rb, 146Sm, 147Sm, 234U, 235U, and 238U (IUPAC Technical Report)
Authors: Villa Igor M. , Holden Norman E. , Possolo Antonio , Ickert Ryan Ben , Hibbert David Brynn , Renne Paul R. , Bonardi Mauro L. , De Bièvre Paul 
Published: September 2022

Abstract
The IUPAC–IUGS joint Task Group “Isotopes in Geosciences” (TGIG) has evaluated the published literature on the half-lives of six long-lived, geologically relevant radioactive nuclides. Where conflicting literature estimates are present, it is necessary to first identify any systematic bias in accordance with metrological traceability and to exclude the biased estimates from further consideration. The TGIG recommends three robust half-life estimates: 49.61 ± 0.16 Ga for 87Rb, corresponding to a decay constant λ(87Rb) = (1.3972 ± 0.0045) × 10−11 a−1; 106.25 ± 0.38 Ga for 147Sm, and a corresponding decay constant λ(147Sm) = (6.524 ± 0.024) × 10−12 a−1; 4.4683 ± 0.0096 Ga for 238U, i.e. a decay constant λ(238U) = (1.55125 ± 0.00333) × 10−10 a−1. All cited uncertainties have a coverage factor k = 2. For other radionuclides of Sm and U, no unambiguous consensus value can be endorsed at present by TGIG, which limits its evaluation to a status report highlighting unaccounted-for potential sources of bias. The improved repeatability of mass spectrometric measurements has revealed systematic bias effects that had been dismissed as subordinate in the past. These issues can only be resolved by future dedicated investigations.
Target preparation of low-pressure cold-sprayed metal powder coatings to create defined micro-leakage
Authors: Kappertz M. , Hoven C. , Pauly F. , Lohoff R. , Natour G. 
Published: September 2022

Abstract
Defined micro-leaks have been used as reference leaks in non-destructive testing for many years, for example in the adjustment, calibration and functional testing of helium leak detectors. Test leaks are also used in non-destructive testing training to teach the staff how to detect these “invisible” leaks.
The traditional production of test specimens with defined leakage, however, is timecon suming and expensive. In addition, these specimens are susceptible to impacts and can break easily.
A new approach for producing robust specimens with defined leakage is gas dynamic cold spraying, or cold spraying, where a very small opening is closed using an open-pore metal powder filling. This manufacturing process is particularly suitable for industrial purposes due to the good controllability of the production process. Unlike traditionally manufactured glass bodies, the specimens produced in this way are less susceptible to mechanical impacts.
The present study is concerned with the metallographic examination of porous coatings to create defined leaks using cold spraying.
Role of science in environmental conservation leading to sustainable development
Authors: Ganesan Subbulakshmi , Rajiv Asha 
Published: September 2022

Abstract
Sustainable development is the development of people’s needs without harming the environment. From this study we would like to discuss how to apply basic science for sustainable development. Most of the time people do not think about the environment during development projects. They only think about their profits. As a result of these unplanned development projects, so much harm occurs to the environment such as water pollution, air pollution, climatic changes, global warming and greenhouse effect. Loss of biodiversity is another crucial problem occurs due to industrial revolution. Most of the time people cut forests and trees for different development projects. Because of these activities many animals lost their habitats and so many plants and natural water resources get destroyed. Do not stop development projects but should think twice before doing any action that harmful to the environment and also it will affect directly or indirectly to animals and mankind. Basic and General science provide good solution for the problems that have created due to industrial activities.
The link between epigenetics, pain sensitivity and chronic pain
Authors: Giordano Rocco , Kjær-Staal Petersen Kristian , Arendt-Nielsen Lars 
Published: September 2022

Abstract
Increasing evidence suggests an association between gene expression and clinical pain. Epigenetic modifications are the main modulators of gene expression or protein translation in response to environmental stimuli and pathophysiological conditions. Preclinical and clinical studies indicate that epigenetic modifications could also impact the development of pain, the transition from acute to chronic pain, and the maintenance hereof.
Tunable properties of the defect mode of a ternary photonic crystal with a high T
C superconductor and semiconductor layers
Authors: Almawgani Abdulkarem H. M. , Alhamss Dana N. , Taya Sofyan A. , Abohassan Khedr M. , Alhawari Adam R. H. , Colak Ilhami , Patel Shobhit K. 
Published: September 2022

Abstract
The tuning of a defect mode in a photonic crystal (PC) is of high significance for filter and sensor applications. We here investigate the tuning of the defect mode of a defective ternary PC with a semiconductor and high critical-temperature superconductor layers. A ternary photonic crystal with the heterostructure (semiconductor/superconductor/dielectric) is assumed. The transfer matrix method is employed to investigate the transmission of transverse electric waves. The refractive indices of the semiconductor and superconductor layers can be tuned by changing the operating temperature and the hydrostatic pressure. The defect mode and transmission properties can be controlled by using the hydrostatic pressure, operating temperature, frequency and thicknesses of the heterostructure layers. The analysis is performed in the frequency range of 20–65 THz. The proposed structure can be utilized as a biosensor and a narrowband transmission peaks filter.
Surround Inhibition Mediates Pain Relief by Low Amplitude Spinal Cord Stimulation: Modeling and Measurement
Authors: Gilbert John E. , Titus Nathan , Zhang Tianhe , Esteller Rosana , Grill Warren M. 
Published: September 2022

AbstractLow-frequency (<200 Hz), subperception spinal cord stimulation (SCS) is a novel modality demonstrating therapeutic efficacy for treating chronic neuropathic pain. When stimulation parameters were carefully titrated, patients experienced rapid onset (seconds–minutes) pain relief without paresthesia, but the mechanisms of action are unknown. Using an integrated computational model and in vivo measurements in urethane-anesthetized rats, we quantified how stimulation parameters (placement, pulse width, frequency, and amplitude) influenced dorsal column (DC) axon activation and neural responses in the dorsal horn (DH). Both modeled and recorded DC axons responded with irregular spiking patterns in response to low-amplitude SCS. Maximum inhibition of DH neurons occurred at ∼80% of the predicted sensory threshold in both modeled and recorded neurons, and responses were strongly dependent on spatially targeting of stimulation, i.e., the complement of DC axons activated, and on stimulation parameters. Intrathecal administration of bicuculline shifted neural responses to low-amplitude stimulation in both the model and experiment, suggesting that analgesia is dependent on segmental GABAergic mechanisms. Our results support the hypothesis that low-frequency subperception SCS generates rapid analgesia by activating a small number of DC axons which inhibit DH neuron activity via surround inhibition.