bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors contributing to parental stress among Chinese families of children with autism: A qualitative study
Authors: Huang Mary , Zhou Zheng 
Published: December 2022

AbstractAutism spectrum disorder (ASD) is a pervasive developmental disorder that has grown in prevalence over the past few decades and has a tremendous impact on families that struggle with adjustment to this disorder. Initial exposure to such a disorder may be a significant source of stress and tribulation for Chinese families who are not familiar with mental health discourse and how to navigate community healthcare systems. More extensive research with this population is vital to understand how cultural values and perceptions of parenting self‐efficacy contribute to parenting stress and coping in Asian families. This qualitative study sought to gain understanding of the ways that Asian families coped with stress when they had a child diagnosed with ASD. Seven Chinese families living in New York, with children between the ages of two and five, who were diagnosed with ASD, participated in semi‐structured interviews. Thematic analyses generated primary themes that explored factors contributing to Chinese parental stress: Chinese parents’ perceived parenting self‐efficacy, parents’ adherence to traditional Asian values, parental patterns of coping, and overall satisfaction with the early intervention services which their children were receiving. Results can guide specialized assessment and intervention for professionals who work with Chinese families within clinical, school, and community settings. Implications for practices of psychology in schools, limitations of this current study, and future directions are also discussed.
Validation of the Lee‐Jones theoretical model of fear of cancer recurrence among breast cancer survivors using a structural equation modeling approach
Authors: Lucas Alexander R. , Pan Jun‐hao , Ip Edward H. , Hall Daniel L. , Tooze Janet A. , Levine Beverly , Mohr David C. , Penedo Frank J. , Cella David , Wagner Lynne I. 
Published: December 2022

AbstractObjectiveThe Lee‐Jones model posits that antecedent individual and interpersonal factors predicate the development of fear of cancer recurrence (FCR) through cognitive and emotional processing, which further to behavioral, emotional, and/or physiological responses. We analyzed data from FoRtitude, a FCR intervention grounded in the Lee‐Jones FCR model, to evaluate associations between FCR antecedents, resources (e.g., breast cancer self‐efficacy, BCSE) and psychological and behavioral consequences.MethodsWomen with breast cancer who completed treatment and reported clinically elevated levels of FCR were randomized into a 4‐week online psychosocial intervention or contact control group. We assessed BCSE, FCR, and physical activity, anxiety and depression, or symptoms at baseline, 4 and 8 weeks. Separate structural equation models were constructed with both baseline data and change scores (baseline‐8 weeks) to examine the pathways linking BCSE, FCR and: (1) physical activity; (2) anxiety and depression; and (3) symptoms (fatigue, sleep disturbance, cognitive concerns).ResultsAt baseline, higher levels of BCSE were associated with lower levels of FCR. Higher FCR was associated with worse psychological effects and symptoms but not behavioral response. Change models revealed that an increase in BCSE was associated with a decrease in FCR at 8‐week assessment, which was associated with reductions in psychological effects. A change in BCSE was also directly associated with reductions in psychological effects.ConclusionsResults support the Lee‐Jones model as a foundation for FCR interventions among breast cancer survivors. Replicability among varied populations is needed to examine effects on behavioral outcomes of FCR such as health care utilization.Clinical Trials Registration: NCT03384992.
CMM—An enhanced platform for interactive validation of metal binding sites
Authors: Gucwa Michal , Lenkiewicz Joanna , Zheng Heping , Cymborowski Marcin , Cooper David R. , Murzyn Krzysztof , Minor Wladek 
Published: December 2022

AbstractMetal ions bound to macromolecules play an integral role in many cellular processes. They can directly participate in catalytic mechanisms or be essential for the structural integrity of proteins and nucleic acids. However, their unique nature in macromolecules can make them difficult to model and refine, and a substantial portion of metal ions in the PDB are misidentified or poorly refined. CheckMyMetal (CMM) is a validation tool that has gained widespread acceptance as an essential tool for researchers working on metal‐macromolecule complexes. CMM can be used during structure determination or to validate metal binding sites in structural models within the PDB. The functionalities of CMM have recently been greatly enhanced and provide researchers with additional information that can guide modeling decisions. The new version of CMM shows metals in the context of electron density maps and allows for on‐the‐fly refinement of metal binding sites. The improvements should increase the reproducibility of biomedical research. The web server is available at https://cmm.minorlab.org.
Analysis of family histories suggests shared genetic risk for chronic thromboembolic pulmonary hypertension and venous thromboembolism
Authors: Dodson Mark W. , Cirulis Meghan M. , Elliott C. Gregory 
Published: December 2022

AbstractChronic thromboembolic pulmonary hypertension (CTEPH) and acute pulmonary embolism (PE) are related phenotypes, however, previous reports have suggested that genetic risk factors for CTEPH and PE differ. Here we report that a family history of VTE is equally frequent in individuals with CTEPH and PE, suggesting that shared genetic variants may influence risk of both phenotypes. We also provide the first estimate of the frequency of familial CTEPH, which we identified in 2.2% of CTEPH patients in our cohort.
Robust adaptive control for spacecraft attitude synchronization subject to external disturbances: A performance adjustable event‐triggered mechanism
Authors: Hu Wenfeng , Li Zichuang , Dai Ming‐Zhe , Huang Tingwen 
Published: December 2022

SummaryThis article addresses the leader‐following synchronization problem of multiple rigid spacecraft systems affected by external disturbances with the directed topology. An event‐triggered distributed observer is proposed to estimate the leader's state. By integrating a performance adjustable function (PAF) into the event‐triggered mechanism, the sampling frequency and estimation speed can be adjusted. Based on the event‐triggered distributed observer, an adaptive event‐triggered control scheme is proposed to aganist the external disturbances. With the adaptive event‐triggered control scheme, continuous communication between spacecraft is no longer required and Zeno‐free property can be guaranteed. The effectiveness of the theoretical results is verified by a numerous example.
Morphological response of the upper Yangtze Estuary to changes in natural and anthropogenic factors
Authors: Zhang Jiayue , Wang Zhichao , Dong Zhangzhan , Zhou Yuyan , Li Zijun , Cui Yurong , Zheng Shuwei 
Published: December 2022

AbstractGlobally, over the past few decades, extreme river channel deformation has been observed downstream of dams. Specially, estuarine channel deformation and its response to natural and anthropogenic factors are key issues influencing channel regulation and prediction of long‐term stability in large estuarine deltas. Herein, bathymetry data for the upper reaches of the Yangtze Estuary (YE), China was collected for the years 1995, 2003, 2008, 2013, and 2019 to analyze the channel deformation process. Our findings show that the total erosion volume was approximately 11.22 × 108 m3, an equivalent of 15.7 × 108 t of sediment assuming a bulk density of 1.4 t/m3 for the riverbed material during 1995–2019. Meanwhile, the annual erosion rate is 0.63 Mt/year in 1995–2019, and the annual erosion rate is 0.90, 0.12, 0.40 Mt/year in 1995–2003, 2008–2013 and 2013–2019, respectively. Meanwhile, the annual deposition rate is 0.7 Mt/year during 2003–2008. Further analysis indicated that continuous reduction of the sediment load due to the construction of dams (e.g., the Three Gorges Dam) in the basin was a key factor influencing channel erosion over the past 24 years. The channel deformation process was characterized by severe erosion during 1995–2003, a deposition period during 2003–2008, a dynamic equilibrium period from 2008–2013, and an erosion period after 2013. Due to floods with maximum peak discharge lower than 70,000 m3/s, despite the annual sediment load is reduced, the channel deposition phenomenon occurred in 2003–2008. The channel changed from a depositional system to an erosion system during 2008–2013. After 2013, the channel was dominated by extensive erosion, severe local deposition, or severe local erosion as a response to anthropogenic interventions. These findings are of great significance to river management and regulation, as well as to the navigational safety.
Science faculty conceptions of equity and their association to teaching practices
Authors: Russo‐Tait Tatiane 
Published: December 2022

AbstractEquity in education has been conceptualized in various ways, which provides different affordances and constraints for policy, research, and teaching decisions. Regarding the latter, there is a dearth of research on how postsecondary science faculty conceptualize equity and whether and how their understandings of equity may be informing their teaching and related practices. This study examined equity conceptions and reported teaching practices among 45 faculty members in a College of Sciences at a research intensive, historically White, public university in the United States. Thematic analysis showed that faculty conceptualized equity in three ways—“equality,” “inclusion,” or “justice”—and these conceptions were associated with instructor‐centered or student‐centered practices. Professors with “equality” conceptions of equity tended to report teaching mostly via lecture, while those with “inclusion” conceptions reported using active learning and/or inclusive teaching practices. Most professors with a “justice” conception went beyond active learning and inclusive practices to also include an emerging critical pedagogy. Conceptions of equity appear to inform how university science faculty see their roles in advancing equity in their classrooms. These findings provide a foundation for future research that seeks to support college science faculty's understandings of equity issues in higher education and the pedagogical practices necessary to ameliorate them.
Magneto‐Nanomechanical Array Biosensor for Ultrasensitive Detection of Oncogenic Exosomes for Early Diagnosis of Cancers
Authors: Mei Kainan , Yan Tianhao , Wang Yu , Rao Depeng , Peng Yongpei , Wu Wenjie , Chen Ye , Ren Min , Yang Jing , Wu Shangquan , Zhang Qingchuan 
Published: December 2022

AbstractExosomes are a class of nanoscale vesicles secreted by cells, which contain abundant information closely related to parental cells. The ultrasensitive detection of cancer‐derived exosomes is highly significant for early non‐invasive diagnosis of cancer. Here, an ultrasensitive nanomechanical sensor is reported, which uses a magnetic‐driven microcantilever array to selectively detect oncogenic exosomes. A magnetic force, which can produce a far greater deflection of microcantilever than that produced by the intermolecular interaction force even with very low concentrations of target substances, is introduced. This method reduced the detection limit to less than 10 exosomes mL−1. Direct detection of exosomes in the serum of patients with breast cancer and in healthy people showed a significant difference. This work improved the sensitivity by five orders of magnitude as compared to that of traditional nanomechanical sensing based on surface stress mode. This method can be applied parallelly for highly sensitive detection of other microorganisms (such as bacteria and viruses) by using different probe molecules, which can provide a supersensitive detection approach for cancer diagnosis, food safety, and SARS‐CoV‐2 infection.
Toward Efficient Wound Management: Bioinspired Microfluidic and Microneedle Patch
Authors: Wang Yuqiu , Gao Bingbing , He Bingfang 
Published: December 2022

AbstractMicroneedle (MN) patches hold demonstrated prospects in intelligent wound management. Herein, inspired by the highly folded structure of insect wings, a three‐dimensional (3D) origami MN patch with superfine miniature needle structures, microfluidic channels, and multiple functions was reported to detect biomarkers, release drugs controllably and monitor motions to facilitate wound healing. By simply replicating the pre‐stretched silicone rubber (Ecoflex) molds patterned by a laser engraving machine, the superfine structure MN patch with microfluidic channels was obtained from the restored molds. The bioinspired origami structure endows the MN patch with a high degree of functional integration, including microfluidic channels and electrocircuits. The microfluidic channels combined with the pH value and glucose concentration indicators enable the patch with the capability of biomarker sensing detection. Porous structures, a temperature‐responsive hydrogel, and a photothermal‐sensitive agent are utilized to form a controllable drug release system on the MN patch. Meanwhile, MXene electrocircuits were printed on the MN patch for motion sensing. In addition, the ability of the MN patch to accelerate wound healing was demonstrated by a mouse model experiment with full‐thickness skin wounds. These results indicate that the multifunctional 3D origami MN patch is a valuable intelligent strategy for wound management.
Assessing veterinary professionals’ ability to estimate length
Authors: Frapwell Emily , Filipas Malina Carmen , Alexander Akash 
Published: December 2022

AbstractBackgroundThis study aimed to assess the accuracy of veterinary professionals’ psychomotor and visual estimation of lengths.MethodsMembers of staff at a single veterinary referral hospital were asked a series of demographic questions. Respondents were first asked to draw lines of a specified length, while being blinded to their previous responses. Respondents were then shown lines on separate non‐standard‐size laminated sheets of paper and asked to estimate their length. A total of five estimations were made in each section, with lengths varying from 3 to 120 mm.ResultsA total of 101 respondents were assessed. The median absolute percentage error was 24.4% for psychomotor estimation and 33.3% for visual estimation. Respondents were significantly more accurate at psychomotor than visual estimation (p = 0.00024). Respondents tended to underestimate with psychomotor estimation and overestimate with visual estimation. There was no significant difference between the accuracy of veterinarians and veterinary nurses.LimitationWhen divided by demographic, not all sample sizes met the power calculation threshold, thus limiting their interpretation.ConclusionVeterinary professionals must recognise the limitations of estimating length using visual appraisal alone. Measuring devices should be utilised where appropriate.
Host and viral RNA dysregulation during BK polyomavirus infection in kidney transplant recipients
Authors: Yaghobi Ramin , Afshari Afsoon , Roozbeh Jamshid 
Published: December 2022

AbstractEarly detection of BK polyomavirus (BKPyV) infection in kidney transplant recipients (KTRs) would enhance their quality of life and save the allograft. Still, many patients lose their grafted kidneys because of this infection. BKPyV microRNAs (miRNAs) have been detected in KTRs during viral infection. BKPyV produces two mature miRNAs that are named BKV‐miR‐B1‐5p and BKV‐miR‐B1‐3p. Additionally, BKPyV associated nephropathy (BKVAN) in kidney transplanted patients cause changes in the expression level of host genes and miRNAs such as IFN‐ɣ, BCLA2A1, has‐miR‐10, and has‐miR‐30a. BKVAN can alter viral genes and miRNAs expression level, too, like viral miRNAs and T‐Ag. However, their potential value as viral infection markers and the regulatory network produced by their expression during viral‐host interactions needs more consideration since there are no approved medications for treating BKPyV‐related diseases in KTRs. Hence, it is vital to recognize complicated facts regarding the impact of BKPyV infection on the distribution of miRNAs and mRNAs within the host cell and the virus.This article is categorized under:
Translation > Regulation
RNA Processing > Processing of Small RNAs
RNA in Disease and Development > RNA in Disease
Supersymmetric quantum chiral higher spin gravity
Authors: Tsulaia Mirian , Weissman Dorin 
Published: December 2022

Abstract
We study quantum properties of supersymmetric $$ \mathcal{N} $$
N
= 1 and $$ \mathcal{N} $$
N
= 4 extensions of the four dimensional bosonic Chiral Higher Spin Gravities (HiSGRAs). We discuss the spectra, the classical actions and define the Feynman rules in $$ \mathcal{N} $$
N
= 1 and $$ \mathcal{N} $$
N
= 4 superspaces in the light-front gauge. Using these Feynman rules, we compute tree and one-loop amplitudes for these systems. A dimensional reduction to a system with $$ \mathcal{N} $$
N
= 2 supersymmetry and with massive higher spin fields is performed and quantum properties of this system are discussed.
On the geometry of the orthogonal momentum amplituhedron
Authors: Łukowski Tomasz , Moerman Robert , Stalknecht Jonah 
Published: December 2022

Abstract
In this paper we focus on the orthogonal momentum amplituhedron $$ \mathcal{O} $$
O
k, a recently introduced positive geometry that encodes the tree-level scattering amplitudes in ABJM theory. We generate the full boundary stratification of $$ \mathcal{O} $$
O
k for various k and conjecture that its boundaries can be labelled by so-called orthogonal Grassmannian forests (OG forests). We determine the generating function for enumerating these forests according to their dimension and show that the Euler characteristic of the poset of these forests equals one. This provides a strong indication that the orthogonal momentum amplituhedron is homeomorphic to a ball. This paper is supplemented with the Mathematica package orthitroids which contains useful functions for exploring the structure of the positive orthogonal Grassmannian and the orthogonal momentum amplituhedron.
Petrogenesis of extra-large flake graphite at the Bissett Creek deposit, Canada
Authors: Drever Cameron , Kinney Carson , Yakymchuk Chris 
Published: December 2022

AbstractThe petrogenesis of extra-large flake graphite is enigmatic. The Bissett Creek graphite deposit, consisting of flake graphite hosted in upper-amphibolite facies quartzofeldspathic gneisses and rare aluminous gneisses, provides an analogue for graphite exploration. In the Bissett Creek gneisses, graphite is homogeneously distributed and composes 2–10 vol. % of the rocks. Disseminated graphite flakes (~ 1 to 6 mm in size) are interleaved with biotite and are petrologically associated with upper-amphibolite facies metamorphic mineral assemblages. Thermobarometry and phase equilibrium modeling yield peak temperatures of > 760 °C at 0.5–0.9 GPa. Whole-rock samples with abundant graphite yield δ13CVPDB from − 28 to − 14‰. δ34SVCDT values of sulfide-bearing samples vary from 10 to 15‰. Sulfur and carbon isotope values are compatible with a biogenic origin, flake graphite probably formed from metamorphism of in situ organic material. However, the variability of δ13C values from the deposit along with graphite microstructures suggest that carbon-bearing metamorphic fluid (or melt) generated during metamorphism may have remobilized carbon resulting in anomalously large to extra-large flake sizes. This may be a common mechanism globally to explain large graphite flake sizes where graphite formed through in situ metamorphism of organic matter is coarsened due to remobilization of CO2-rich fluids (or melt) during high-temperature metamorphism.
Fast calculation of gravitational effects using tesseroids with a polynomial density of arbitrary degree in depth
Authors: Ouyang Fang , Chen Long-wei , Shao Zhi-gang 
Published: December 2022

AbstractFast and accurate calculation of gravitational effects on a regional or global scale with complex density environment is a critical issue in gravitational forward modelling. Most existing significant developments with tessroid-based modelling are limited to homogeneous density models or polynomial ones of a limited order. Moreover, the total gravitational effects of tesseroids are often calculated by pure summation in these methods, which makes the calculation extremely time-consuming. A new efficient and accurate method based on tesseroids with a polynomial density up to an arbitrary order in depth is developed for 3D large-scale gravitational forward modelling. The method divides the source region into a number of tesseroids, and the density in each tesseroid is assumed to be a polynomial function of arbitrary degree. To guarantee the computational accuracy and efficiency, two key points are involved: (1) the volume Newton’s integral is decomposed into a one-dimensional integral with a polynomial density in the radial direction, for which a simple analytical recursive formula is derived for efficient calculation, and a surface integral over the horizontal directions evaluated by the Gauss–Legendre quadrature (GLQ) combined with a 2D adaptive discretization strategy; (2) a fast and flexible discrete convolution algorithm based on 1D fast Fourier transform (FFT) and a general Toepritz form of weight coefficient matrices is adopted in the longitudinal dimension to speed up the computation of the cumulative contributions from all tesseroids. Numerical examples show that the gravitational fields predicted by the new method have a good agreement with the corresponding analytical solutions for spherical shell models with both polynomial and non-polynomial density variations in depth. Compared with the 3D GLQ methods, the new algorithm is computationally more accurate and efficient. The calculation time is significantly reduced by 3 orders of magnitude as compared with the traditional 3D GLQ methods. Application of the new algorithm in the global crustal CRUST1.0 model further verifies its reliability and practicability in real cases. The proposed method will provide a powerful numerical tool for large-scale gravity modelling and also an efficient forward engine for inversion and continuation problems.
Free groups generated by two parabolic maps
Authors: Kalane Sagar B. , Parker John R. 
Published: December 2022

AbstractIn this paper we consider a group generated by two unipotent parabolic elements of$$\textrm{SU}(2,1)$$SU(2,1)with distinct fixed points. We give several conditions that guarantee the group is discrete and free. We also give a result on the diameter of a finite$${\mathbb R}$$R-circle in the Heisenberg group.
Uniqueness of Unitary Structure for Unitarizable Fusion Categories
Authors: Reutter David 
Published: December 2022

AbstractWe show that every unitarizable fusion category, and more generally every semisimple $$\textrm{C}^*$$

C
∗

-tensor category, admits a unique unitary structure. Our proof is based on a categorified polar decomposition theorem for monoidal equivalences between such categories. We prove analogous results for unitarizable braided fusion categories and module categories.