bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pelatihan Pengenalan Inovasi Usaha Melalui Sosial Media di Desa Lamanda Kab Bulukumba
Authors: Parenden Adrianus , Hatidja St 
Published: December 2022

Tujuan PKM adalah 1) untuk memberi pelatihan dan pendampingan kepada masyarakat yang berdomisili di Desa Lamanda Kabupaten Bulukumba khususnya penggunaan sosial media untuk meningkatkan usaha dalam rangka menunjang peningkatan perekonomian keluarga dan kesejahteraan warga secara keseluruhan dan 2) memberi pelatihan inovasi usaha untuk meningkatkan daya jual produk. Metode kegiatan yang dilaksanakan dimulai dari survey awal, identifikasi permasalahan mitra, pelatihan dan pendampingan dan tahap terakhir adalah monitoring dan evaluasi. Kesimpulan dari kegiatan PKM adalah peserta sudah mampu menggunakan media sosial untuk memasarkan produk, serta peserta sudah mengetahui pentingnya inovasi produk untuk meningkatkan daya jual.
Non-invasive Polarimetric diagnostics of biological tissues aided by Artificial Neural Networks II
Authors: Doronin Alexander , Novikova Tatiana , Robinson Brian , Yakovlev Vladislav 
Published: December 2022

As a part of our collaboration with Ecole Polytechnique, France and Texas A M University, USA we are excited to be able to host an in-person seminar this year, which will also be broadcast online.We cordially invite you to the talks which will feature world-renowned experts in biomedical optical imaging/light transport theory.IntroductionDr. Alexander Doronin is chairing the seminar and facilitating the panel discussion.Recent advances in polarimetric imaging for tissue diagnosisOptical polarization has proven its potential to for a fast and non-contact optical diagnosis of biological tissues in medical applications. We focus our studies on Mueller polarimetry – the optical technique that provides access to the complete set of polarimetric properties of a sample, including diattenuation, retardance and depolarization, which serve as the optical markers of tissue pathology. The recent advances in using custom-built imaging Mueller polarimeters operating in a visible wavelength range and based on the ferro-electric liquid crystals will be reported for a wide range of pre-clinical and clinical applications, including gastroenterology, gynecology and neurosurgery.Why leave clinical decision making to machinesMachine learning will have many implications on how medical technologies are developed. This presentation will describe how biases and errors occur in clinical decision making, identify strategies developed and applied to address the causes of biases and errors and where data collection and analysis can potentially benefit health outcomes.Seeing life in a new light: from simple classical physics to quantum-enhanced imagingThe progress of biomedical sciences depends on the availability of advanced instrumentation and imaging tools capable of attaining the state of biological systems in vivo without using exogenous markers. Mechanical forces and local elasticity play a central role in understanding physical interactions in all living systems. We demonstrate a novel way to image microscopic viscoelastic properties of biological systems using Brillouin microspectroscopy. In my talk, I will discuss the ways how an old spectroscopic tool can be used for real time microscopy and provide possible solutions to long standing problems in Life Sciences and Medicine while advancing instrumentation beyond classical limits.
Preface: 2022 International Conference on Advances in Financial Technology and Economic Management (AFTEM 2022)
Authors: Cromwell Patricia , Liu Meng 
Published: December 2022

The 2022 International Conference on Advances in Financial Technology and Economic Management (AFTEM 2022) was held during September 10-11, 2022 in Lyon, France. Aiming at providing an excellent international academic forum for all the researchers and practitioners, the conference enjoys a wide spread participation among all over the universities and research institutes.
AFTEM 2022 provides opportunities for the delegates to exchange new ideas and application experiences, establishes business or research relations and global partners for future collaboration. This conference proceeding tends to collect the most up-to-date, comprehensive, and worldwide state-of-art knowledge on financial technology, economic management, business, marketing and other related topics. All the accepted papers have been submitted to strict peer-review by 2-3 expert referees. The conference program is extremely rich, profound and featuring high-impact presentations of selected papers and additional late-breaking contributions.
We sincerely hope that the conference would not only show the participants a broad overview of the latest research results on related fields, but also provide them with a significant platform for academic connection and exchange. We would like to express our sincere gratitude to all the keynote speakers, editors and organizers for their hard work, precious time and endeavor preparing for the conference. Our deepest thanks also go to the volunteers and staffs for their long-hours work. We would like to thank each and every of the authors, speakers and participants for their great contributions to the success of AFTEM 2022.
Organizing Committees of AFTEM 2022
Lyon, France
Research and Solution of Management Problems in Huawei's "Internationalization" Business Development
Authors: Xia Yuming 
Published: December 2022

Huawei Technologies Co., Ltd., as the representative of the successful internationalization of China's communication equipment manufacturing enterprises, its internationalization strategy and implementation experience are of great significance for Chinese enterprises to go global and realize the worldwide layout and development. This paper expounds and analyses Huawei's internationalization strategy from the perspectives of market internationalization, brand internationalization, R&D internationalization, and talent internationalization. Taking Huawei's entry into the global market as an example, it analyses the background, process, and problems of Huawei's internationalization development path and summarizes the experience and lessons. This paper will also help Huawei solve the existing issues from four aspects: strengthening international cooperation, combining with the national foreign policy, breaking through the research and development of core technologies independently or cooperatively, and applying the equity incentive system. This paper can provide a reference for the internationalization development path of Chinese enterprises and avoid similar problems and difficulties.
PELAKSANAAN FUNGSI-FUNGSI MANAJEMEN DALAM PENINGKATAN MUTU LEMBAGA PENDIDIKAN ISLAM
Authors: Mubarok Ramdanil 
Published: December 2022

The implementation of management functions is very important to regulate all activities, both formal and informal activities. An Islamic educational institution requires good management planning. Whether or not an Islamic educational institution is determined by how the implementation of management functions in the educational institution. In reality, the problems faced by Islamic educational institutions are so diverse. Starting from management problems, leadership problems, human resources, financial, and institutional problems.
Good management certainly refers to the management functions themselves, where the intended functions are none other than POAC. Management must be applied in an effort to improve the quality of Educational Institutions because by applying management aspects such as planning, organizing, actuating, and controlling, the quality of educational institutions can be improved because of the implementation of management functions in a planned manner, systematic, sustainable and achieve the goals that have been created in this case educational institutions can achieve predetermined quality standards of education.
Improving the quality of educational institutions can be achieved through the collectivity of the education system which involves various aspects such as curriculum, educational policies, materials, strategies, approaches and methods of learning, facilities, facilities and infrastructure, educators and education staff, managerial processes carried out professionally, the learning process, application of information and communication technology, especially in the learning process in the classroom, appropriate evaluation and control and quality control of education. Quality in educational institutions to ensure the quality of school inputs, processes, outputs and outcomes so as to increase the accountability of educational institutions.
THE EFFICIENCY OF USING NITROGEN FERTILIZERS IN WHEAT CROP
Authors: Alina Laura AGAPIE  , Nicolae Marinel HORABLAGA  , Cristian BOSTAN  , Diana POPA  
Published: December 2022

Nitrogen has its undeniable role in increasing crop productivity and quality. However, used improperly, it can cause serious environmental damage. Increasing the efficiency of the use of chemical nitrogen fertilizers (NUE) is a goal of the future¸ necessary for a sustainable and competitive agriculture. The wheat crop studied is part of a long-term experiment, established in Lovrin in 1967. The experimental factors studied are: factor A - nitrogen, with the following graduations: N0, N30, N60, N90 and N120 and factor B - phosphorus, with the following graduations: P0, P40, P80, P120 and P160. From the combination of the two studied factors results 25 experimental variants, placed in the field according to the method of subdivided plots, in four repetitions. Chemical fertilizers with phosphorus - 46% superphosphate - were administered to the wheat crop in autumn and were incorporated under the basic plowing. Nitrogen fertilizers - 33.5% ammonium nitrate - were applied in fractions: 40% of the dose at start of vegetation, in the spring and 60% at straw elongation. The wheat culture is part of a three-year crop rotation - soybeans-wheat-corn. Following in rotation after soybeans, no nitrogen fertilizers were applied at the establishment of the crop. The variety studied is the Ciprian variety, created at SCDA Lovrin. For the evaluation of NUE, Plant N Uptake, Nitrogen Use Effciency and Partial Factor Productivity were analyzed in this paper. In the climatic conditions of the two experimental years, a distinctly significant positive correlation is established between the nitrogen dose administered and production, the value of the correlation coefficient being 0.56 **. Between the nitrogen dose, the protein content and the amount of protein per ha the correlation is very significant, with the following values ​​of the correlation coefficients: r = 0.96 *** (for protein) and r = 0.90 *** (for N uptake). Nitrogen use efficiency correlates negatively, very significantly, with the administered dose - r = -0.87 ***. This study also reveals the importance of phosphorus in the absorption and accumulation of nitrogen in wheat caryopsis. The amount of nitrogen accumulated increases with increasing dose of phosphorus, up to 80 kg ha-1, with the gradual reduction of the amount accumulated to high values ​​of phosphorus administered (120 kg ha-1 and 160 kg ha-1, respectively).
INFLUENCE OF NP MINERAL FERTILIZATION ON SOYBEAN CROPS
Authors: ȘIMON Alina , CECLAN Adrian , RUSSU Florin , BĂRDAȘ Marius , CHEȚAN Felicia , POPA Alin 
Published: December 2022

Soybean is one of the most important sources of vegetable protein, having a great agronomic importance by fixing atmospheric nitrogen following symbiosis with bacteria of the genus Rhizobium. Bifactorial experience, of the AxB model A - phosphorus doses: P0; P40; P80; P120; P16 and B - nitrogen doses:N0; N25; N50; N75; N100, aims to identify the influence of these doses on the development of soybean cultivation. Although soybeans are a heavy consumer of nitrogen and phosphorus in the early stages of development, however, they do not react well to large amounts of nitrogen as they prevent the development of the number of nodules on soybean roots and inhibits the growth of bacteria, and the increases obtained production do not justify the higher amount of nitrogen applied to soybeans. The number of pods and the mass of 1000 grains are also influenced more by the application of phosphorus doses than nitrogen. Phosphorus applied in higher amounts leads to an increase of over 60% of the number of nodules but also at significant production increases of 5-7%, compared to the non-fertilized variant. On nutrient-rich soils, soybeans do not require fertilization with large amounts of nitrogen, but they react very well to the application of phosphorus fertilizers.
Enzymatic Computing
Authors: Zauner Klaus‐Peter , Conrad Michael 
Published: July 2002

AbstractThe conformational dynamics of enzymes is a computational resource that fuses milieu signals in a nonlinear fashion. Response surface methodology can be used to elicit computational functionality from enzyme dynamics. We constructed a tabletop prototype to implement enzymatic signal processing in a device context and employed it in conjunction with malate dehydrogenase to perform the linearly inseparable exclusive‐or operation. This shows that proteins can execute signal processing operations that are more complex than those performed by individual threshold elements. We view the experiments reported, though restricted to the two‐variable case, as a stepping stone to computational networks that utilize the precise reproducibility of proteins, and the concomitant reproducibility of their nonlinear dynamics, to implement complex pattern transformations.
A Computational Study of Feedback Effects on Signal Dynamics in a Mitogen‐Activated Protein Kinase (MAPK) Pathway Model
Authors: Asthagiri Anand R. , Lauffenburger Douglas A. 
Published: July 2002

AbstractExploiting signaling pathways for the purpose of controlling cell function entails identifying and manipulating the information content of intracellular signals. As in the case of the ubiquitously expressed, eukaryotic mitogen‐activated protein kinase (MAPK) signaling pathway, this information content partly resides in the signals' dynamical properties. Here, we utilize a mathematical model to examine mechanisms that govern MAPK pathway dynamics, particularly the role of putative negative feedback mechanisms in generating complete signal adaptation, a term referring to the reset of a signal to prestimulation levels. In addition to yielding adaptation of its direct target, feedback mechanisms implemented in our model also indirectly assist in the adaptation of signaling components downstream of the target under certain conditions. In fact, model predictions identify conditions yielding ultra‐desensitization of signals in which complete adaptation of target and downstream signals culminates even while stimulus recognition (i.e., receptor‐ligand binding) continues to increase. Moreover, the rate at which signal decays can follow first‐order kinetics with respect to signal intensity, so that signal adaptation is achieved in the same amount of time regardless of signal intensity or ligand dose. All of these features are consistent with experimental findings recently obtained for the Chinese hamster ovary (CHO) cell lines (Asthagiri et al.,J. Biol. Chem.1999,274, 27119−27127). Our model further predicts that although downstream effects are independent of whether an enzyme or adaptor protein is targeted by negative feedback, adaptor‐targeted feedback can “back‐propagate” effects upstream of the target, specifically resulting in increased steady‐state upstream signal. Consequently, where these upstream components serve as nodes within a signaling network, feedback can transfer signaling through these nodes into alternate pathways, thereby promoting the sort of signaling cross‐talk that is becoming more widely appreciated.
What criteria reliably distinguish melanoma from benign melanocytic lesions?
Authors: Okun M R , Edelstein L M , Kasznica J 
Published: July 2002

The differential diagnosis of melanocytic lesions is fraught with difficulty and a common source of litigation either if a lesion misreported as ‘benign’ recurs locally or re‐presents with nodal metastases or if an atypical naevus is called ‘malignant’ leading to a cosmetically unsatisfactory wider resection, unwarranted anxiety about prognosis and adverse life insurance prospects. Several authors have claimed that there are valid morphological criteria which, alone or in combination, enable reliable distinction between benign and malignant melanocytic lesions. Others question these criteria and, doubting the extent to which unequivocal diagnoses can be rendered in all cases, believe that the diagnosis is purely subjective and that most diagnostic errors are non‐negligent. To address these issues, expert opinions were commissioned from three sets of authors.Okun, Edelstein & Kasznica emphasize that a significant minority of melanocytic lesions are so borderline morphologically that diagnostic uncertainty is allowable and that such uncertainty can be handled responsibly. Kirkham, in favouring the methodical use of criteria, concedes that they are ‘largely opinion‐based rather than evidence‐based, but do go beyond mere subjective pattern analysis’. In agreement with Okun and his colleagues, Slater emphasises that no single feature is reliable by itself and that all aspects, including clinical details, should be interpreted together; he has no hesitation in reporting the diagnosis as ‘uncertain’ in doubtful cases.In the absence of a specific marker pathognomonic of melanocytic malignancy, the diagnosis will continue to rely on the judicious application of morphological criteria with a small proportion of elusive cases in which diagnostic uncertainty should not be concealed.
Long‐term demographic balance in the Broadstone stream insect community
Authors: Speirs D. C. , Gurney W. S. C. , Hildrew A. G. , Winterbottom J. H. 
Published: July 2002

1. Population models based on Lotka–Volterra‐type differential equations with logistic prey were made for a simple stream community including two stonefly prey Leuctra nigra Olivier and Nemurella pictetii Klàpalek, and two predators, the caddisfly Plectrocnemia conspersa (Curtis) and the alderfly Sialis fuliginosa Pictet. In order to assess the importance of predation in this system, we constructed both an explicit four‐species model and a simplified model with two functional groups which was more amenable to analytical treatment. 2. The models were parameterized using new data on adult emergence and recruitment combined with previously published data on larval densities and prey uptake. The models were falsified if parameterizations led either to negative prey carrying capacities or to unstable dynamics. 3. Both the functional group and four‐species models predict asymptotically stable interactions, with feasible carrying capacities. The models are consistent in predicting that the observed prey are in excess of 70% of their carrying capacities. The four‐species model indicates that predation impact is not evenly shared between the two prey, with L. nigra being depressed further from its carrying capacity than N. pictetii. 4. Sensitivity analysis shows that the results of the full four‐species model remain very robust to realistic levels of stochastic variation in the input data. 5. The four‐species model is used to predict the outcome of an ongoing large‐scale field experiment involving the transfer of all S. fuliginosa eggs from one stretch of the stream to another. Although the equilibrial prey populations are barely affected by the manipulation, the model predicts marked transient prey‐release and prey‐depression of L. nigra in the predator addition and removal areas, respectively.
Squamous cell carcinoma of the lip. Patterns of relapse and outcome: Reporting the Westmead Hospital experience, 1980–1997
Authors: Veness Michael J , Ong Colin , Cakir Burcu , Morgan Gary 
Published: July 2002

SUMMARYAustralia has one of the highest rates of squamous cell carcinoma of the lip in the world. Despite a high cure rate, many studies report relapse rates of between 5% and 20% with an associated mortality of 5–10%. The aim of this study was to review the patterns of relapse and outcome for patients treated at Westmead Hospital, Sydney. Ninety‐three eligible patients were identified in a retrospective review of all lip cancer patients referred to Westmead Hospital between 1980 and 1997. Relevant data were extracted from the treatment files and included contact with referring doctors and utilizing the Cancer Council Registry. Equal numbers of patients were treated with radiotherapy alone or surgery (± adjuvant radiotherapy). The majority of patients were male (78.5%) with T1N0 cancers (64.5%) of the lower lip. A minority (5.4%) had nodal disease at diagnosis. Following treatment, 31 (33.3%) patients relapsed, 11 at the primary site, 18 at the regional nodes and two at both sites simultaneously. Patients treated with a combined approach (RTx/Sx) experienced a better outcome. Overall cancer‐specific survival at 5 years was 85%. These findings highlight a disturbing relapse rate and mortality for a subgroup of patients diagnosed with a more aggressive form of lip cancer. Treatment and follow up of these patients should accordingly be more aggressive.
Expression of periglandular tenascin‐C and basement membrane laminin in normal prostate, benign prostatic hyperplasia and prostate carcinoma
Authors: Xue  , LI  , Latijnhouwers  , Smedts  , Umbas  , Aalders  , Debruyne  , De La Rosette  , Schalken  
Published: July 2002

Objective To evaluate the structural relationship of the distribution between tenascin (tenascin‐C, an extracellular matrix glycoprotein involved in stromal–epithelial interactions in both normal and pathological conditions) and laminin, an important component of the basement membrane, in normal and neoplastic human prostate, and to establish whether changes in the basement membrane are accompanied by changes in tenascin staining.Materials and methods Seventy‐five snap‐frozen prostate samples representing normal glands, nodular benign prostatic hyperplasia and prostate carcinoma were stained for tenascin. From these, 15 samples were selected for dual‐immunofluorescence staining and a confocal laser scan microscope was used to simultaneously visualize tenascin and laminin immunoreactivity.Results Tenascin was expressed in the extracellular matrix, mainly at the periphery of the glands, in tumour foci and blood vessels. In cases with intact basement membranes, e.g. normal glands and hyperplastic lesions, tenascin expression was weak. Low‐ and moderate‐grade tumours were characterized by strong tenascin expression, while laminin expression was weak and/or showed discontinuities, indicating disturbances in basement membrane composition. High‐grade tumours had sparse tenascin staining and a marked loss of laminin immunoreactivity.Conclusion These results indicate that periglandular tenascin expression correlates with the integrity of the basement membrane in the human prostate. By influencing stromal–epithelial interactions, tenascin may play a role in maintaining tissue homeostasis in the prostate.