bluuebunny/crossref_metadata_2025_split huggingface dataset:
Essential Components of Physical Therapist Management of Patients With Osteoporosis: A Delphi Study
Authors: Avin Keith G. , Nithman Robert W. , Osborne Raine , Betz Sherri R. , Lindsey Carleen , Hartley Gregory W. 
Published: March 2022

Background and Purpose:
Osteoporosis is a systemic, metabolic bone disease that affects bone quality, increases susceptibility to low-trauma bone fracture, and has downstream effects on falls and fragility fractures. Osteoporosis is a multifactorial disease process that requires management from multiple health care providers including physicians, nurses, and physical therapists. However, the paucity of information regarding comprehensive physical therapist management for patients with osteoporosis indicated the need for an evidence-based document. The purpose of this document was to provide the best available expert guidance for clinicians in the selection of screening tools, essential tests and measures, treatment goals, and interventions for patients with osteoporosis.

Methods:
A Delphi process was used. Thirty-one physical therapists with expertise in the care of patients with osteoporosis participated in a series of 3 sequential surveys designed to build and reach agreement on the management of patients with osteoporosis. The desired survey outcomes were to: (1) identify the range of examination and plan of care components considered important to physical therapists' care for patients with osteoporosis, (2) determine which components should be considered essential, and (3) achieve consensus on the final list of essential components and related operational definitions.

Results:
A clear consensus on the essential components of examination and interventions was achieved. In general, there were 4 to 6 items across each category of history, tests and measures, education/goals, and treatment.

Conclusions:
The prioritization of these management items will better support clinicians working with adults who have osteoporosis.
KARMA DAN ETOS KERJA DALAM AJARAN BUDHA
Authors: Rusli Ayu Rustriana 
Published: March 2022

This article aims to describe the relation between karma and work ethic in Buddhism which centred to the understanding of karma. There are two understanding of karma, namely: First, karma means the fatalism; Second, karma means optimism. The second meaning related to the work ethic based on Budhisme. One of the concept of karma which most related to the work ethic is Karma Vipaka. It motivates Buddhists always be optimistic, earnest, diligent, tenacious, work hard, be honest, and be responsible for all actions. Based on this concept born the concept of work ethic that emphasizes that nothing will determine the fate of humans except humans themselves.Tulisan ini bertujuan untuk menggambarkan hubungan antara karma dan etos kerja dalam agama Budha yang berpusat pada konsep karma. Ada dua pemahaman tentang karma, yakni: pertama, karma bermakna fatalisme; kedua, karma bermakna optimisme. Makna kedua terkait dengan etos kerja dalam agama Budha. Salah satu konsep karma yang sangat terkait dengan etos kerja adalah Karma Vipaka. Karma ini memotivasi umat Budha untuk selalu optimis, sungguh-sungguh, rajin, ulet, bekerja keras, jujur, dan bertanggung jawab atas semua tindakan. Berdasarkan hal ini lahirlah konsep etos kerja yang menekan bahwa tidak ada yang akan menentukan nasib manusia kecuali manusia itu sendiri.
The Dynamics of Religious Conflict in Indonesia: Contestation and Resolution of Religious Conflicts in The New Order Age
Authors: Takdir Mohammad , Mushthafa M , AS Rozinah 
Published: March 2022

Social conflicts in Indonesia are often associated with political turmoil and disappointment with the hegemony of power. Therefore, it is important to understand comprehensively how the dynamics of religious conflict in Indonesia, especially during the New Order era. As we know that this research is a literature study to understand the contestation of religious conflicts and how conflict resolution was implemented by the government in resolving ethnic-religious conflicts during the New Order era. Using qualitative methods, this study finds that there are several factors of ethnic and religious conflicts in Indonesia, especially during the New Order era, namely group identity conflicts, levels of chaos and social mobilization, repressive actions by power groups, and collective conflicts between communal groups. This study also shows that for the resolution of social conflicts, the government uses a repressive and security approach to control the community, and there is also a cultural approach from civil society as a form of resistance for the government. Civil society also plays an active role in promoting peace agreements between conflicting groups.Konflik sosial di Indonesia seringkali dikaitkan dengan kekacauan politik dan kekecewaan terhadap hegemoni kekuasaan. Karena itu, penting untuk memahami lebih komprehensif bagaimana dinamika konflik agama di Indonesia, khususnya pada masa Orde Baru. Sebagaimana kita ketahui bahwa. Penelitian ini merupakan studi kepustakaan untuk memahami kontestasi konflik agama dan bagaimana resolusi konflik yang diterapkan oleh pemerintah dalam penyelesaian konflik agama-etnis pada masa Orde Baru. Menggunakan metode kualitatif, penelitian ini menemukan bahwa ada beberapa faktor konflik etnis dan agama di Indonesia, khususnya pada masa Orde Baru, yaitu konflik identitas kelompok, tingkat kekacauan dan mobilisasi sosial, tindakan represif oleh kelompok kekuasaan, dan konflik kolektif diantara kelompok komunal. Penelitian ini juga menunjukkan bahwa untuk penyelesaian konflik sosial, pemerintah menggunakan pendekatan represif dan keamanan untuk mengontrol masyarakat, dan juga ada pendekatan budaya dari masyarakat sipil sebagai salah satu perlawanan bagi pemerintah. Masyarakat sipil juga berperan aktif dalam mendorong kesepakatan damai antara kelompok-kelompok yang berkonflik.
Efficacy of Endoscopic Band Ligation in the Treatment of Acute Esophageal Varicose Bleeding
Authors: ÇALIK Mustafa , IRAK Kader 
Published: March 2022

Objective: To determine the efficacy of endoscopic band ligation (EBL) on rebleeding and mortality in the treatment of esophageal varices bleeding.
Methods: Fifty cirrhosis patients who applied to the emergency department with acute esophageal variceal bleeding between 2018 and 2020 and were treated with EBL within the first 12 hours were evaluated retrospectively.
Results: Twenty-seven (54%) patients were male and 23 (46%) were female. The mean hospital stay of the patients was 6.45.6 days, and the mean blood transfusion requirement was 3.62.7 units. Re-bleeding was observed within 30 days in 5 (10%) patients and within 1 year in 7 (14%) patients. Ten (20%) patients died within 30 days, and 11 (22%) patients died within 1 year. The need for blood transfusion was higher in patients with grade 3 varicose veins (4.93.1) than in patients with grade 2 varicose veins (2.51.5) (p=0.001). Mortality rate within 30 days and 1 year was significantly higher in patients with grade 3 varicose veins (p=0.001). Although the rate of bleeding within 30 days and 1 year was higher in patients with grade 3 varicose veins than in patients with grade 2 varices, the difference was not significant (p=0.087).
Conclusion: EBL is an endoscopic treatment method to be preferred in patients with acute esophageal variceal hemorrhage due to its low risk of re-bleeding and low mortality rate.
The Effect of Body Weight on Sleep Quality and Sleep Duration in Adolescents
Authors: YILMAZ Beytül , ÇİÇEK Betül , KANER Gülşah 
Published: March 2022

Aim: The aim of the present study was to determine the effect of body weight on sleep duration and sleep quality in adolescents.
Material and Method: This cross-sectional study was performed on 14-17 year old adolescents (n=1072) attending to public and private high schools. In order to determine the sleep quality, Pittsburgh Sleep Quality Index (PSQI) was filled, and sociodemographic data were collected through a questionnaire. Body weight, height, waist and hip circumferences were measured and body mass index (BMI), waist to hip ratio were calculated.
Results: In the least sleeping group (
Construção de mercados agroalimentares
Authors: Camara Simone , Lago Adriano , dos Santos Amorim Gabrieli , Pietrobelli Valeska , Andreatta Tanice , Marisa Spanevello Rosani 
Published: March 2022

Introdução: O objetivo deste artigo é investigar o papel da Cooperativa Familiar do Extremo Norte Mista de Produção Agroindustrial na Produção e Fornecimento de Alimentos para agricultura familiar, não no município de Alpestre e região.
Metodologia: Trata-se de um estudo exploratório e de abordagem qualitativa, baseado em um estudo de caso. As informações foram coletadas no meio de uma entrevista realizada no máximo em setembro de 2018, conduzida por um roteiro semiestruturado que continua sendo coberto desde a fundação da cooperativa até os canais de comercialização acessados ​​por ela.
Resultados: A Ressalta-se, papel fundamental do Programa Nacional de Alimentação Escolar (PNAE), representa um canal institucional de mercado e marketing cooperativo, com a visão de que a responsabilidade da parte principal da produção e a possibilidade de aumentar a produção do programa intermediário de couro cabeludo direcionado sob demanda.
Conclusões: uma contribuição para reforçar a importância das cooperativas agrícolas para a agricultura familiar e, quando acompanhadas de políticas públicas eficazes, incentivar ou desenvolver agricultores, principalmente em relação às exigências comerciais e legais, além de estimular ou desenvolver o desenvolvimento econômico. e o social não está entrando, notam-se dificuldades em relação aos dias de entrega das instituições e limitações entre um sistema de produção restrito ao sistema cooperativo de dois agricultores.
Pendidikan bagi Perempuan Indonesia : Perjuangan Raden Dewi Sartika dan Siti Rohana Kudus (1904-1928)
Authors: Jayudha Irfan Agung , Darmawan Wawan , Wiyanarti Erlina 
Published: March 2022

ABSTRAKPenelitian ini mengkaji mengenai perbandingan peranan Raden Dewi Sartika dan Siti Rohana Kudus dalam memperjuangkan pendidikan perempuan di Indonesia dengan rentang waktu dari 1904-1928. Latar belakang dalam penelitian ini adalah Raden Dewi Sartika dan Siti Rohana Kudus memiliki pemikiran dan tindakan berbeda dengan perempuan pada umumnya pada masa itu. Keduanya hidup pada zaman yang sama, tetapi berada di daerah yang berbeda. Masalah utama yang diangkat dalam penelitian ini adalah bagaimana perbandingan peranan yang dilakukan oleh Raden Dewi Sartika dan Siti Rohana Kudus dalam memperjuangkan pendidikan bagi perempuan . Metode yang digunakan dalam penelitian ini adalah metode historis dengan menggunakan empat langkah penelitian yaitu heuristik, kritik, interpretasi dan historiografi dengan teknik pengumpulan data menggunakan teknik studi literatur. Berdasarkan hasil penelitian ini, dapat dijelaskan bahwa Raden Dewi Sartika dan Siti Rohana Kudus memiliki persamaan dan juga perbedaan. Persamaan keduanya yakni berkeinginan untuk mengangkat derajat kaum perempuan dengan jalan pendidikan dalam memperjuangkan pendidikan bagi perempuan dengan mendirikan sekolah untuk perempuan dan juga turut aktif dalam pergerakan nasional. Adapula hal yang menjadi landasan kuat bagi keduanya adalah dapat menjadi ibu yang baik bagi anak-anaknya kelak. Akan tetapi, Raden Dewi Sartika dan Siti Rohana Kudus tetap memiliki perbedaan peranan dalam pergerakan nasional dan perbedaan dalam proyeksi lulusan dari sekolah yang keduanya dirikan. Kata Kunci : Pendidikan Perempuan, Raden Dewi Sartika, Siti Rohana Kudus
Changes in levels of urokinase receptor and other components of fibrinolytic system in brain tissues in urokinase gene-knockout mice with B16/F10 melanoma growing together with chronic neurogenic pain
Authors: Frantsiyants E. M. , Bandovkina V. A. , Kaplieva I. V. , Cheryarina N. D. , Surikova E. I. , Neskubina I. V. , Pogorelova Yu. A. , Nemashkalova L. A. 
Published: March 2022

Purpose of the study. An analysis of the changes in components of the urokinase system in the brain of urokinase gene-knockout mice (uPA-/-) with B16/F10 melanoma growing alone and together with chronic neurogenic pain (CNP).Materials and methods. The study included male and female C57BL/6-PlautmI.IBug-ThisPlau6FDhu/GFDhu mice (uPA-/-) (n = 48) and C57BL/6 mice (uPA+/+) (n = 80) with transplanted B16/F10 melanoma growing solitarily and together with CNP. Levels of the urokinase receptor (uPAR) and plasmin (PAP) and activity and levels of the PAI-I inhibitor were measured in the brain of animals by ELISA.Results. Levels of uPAR, PAI-I and PAP in the brain differed only in intact uPA-/- males, being on average 1.6 times higher (p < 0.05) than in uPA+/+ mice. Among animals with CNP, uPA-/- males showed increased PAI-I by 1.3 times (p < 0.05) and decreased PAP by 2.6 times (p < 0.05), while in uPA+/+ males, changes in PAI-I and PAP were opposite; in uPA-/- females, levels of all indicators increased by 1.6–2.1 times (p < 0.05), unlike uPA+/+ females. Among animals with melanoma only, changes in the levels of uPAR, PAI-I and PAP in the brain tissues in uPA-/- males differed from the group with CNP and from uPA+/+ males; in uPA+/+ females, levels of uPAR and PAP increased by 1.7 and 3.0 times (p < 0.05), and only PAP increased in uPA-/- females by 3.2 times (p < 0.05). Combination of CNP with melanoma in uPA-/- mice, regardless of their gender, down-regulated levels of uPAR and PAI-I on the average by 1.5 and 2.0 times, respectively (p < 0.05), and up-regulated PAP on the average by 2.2 times (p < 0.05) compared to the levels in animals with CNP; in uPA+/+ animals, similar decline of uPAR by 3.7 times (p < 0.05) was registered only in males, and an increase of PAI-I by 2.0 times (p < 0.05) was noted in all mice.Conclusion. Changes in the studied parameters in the brain tissue of urokinase gene-knockout animals in response to stress factors indicate the role of the brain urokinase system in the response to both CNP and melanoma growth, and the gender specificity of these changes may be another factor that conditions gender differences in the risk of occurrence and course of cutaneous melanoma.
Inhibition of growth of colorectal cancer patient-derived subcutaneous xenografts using combined Wnt signaling pathway inhibitor and 5‑fluorouracil
Authors: Goncharova A. S. , Galina A. V. , Khodakova D. V. , Egorov G. Yu. , Maksimov A. Yu. , Kolesnikov E. N. , Komarova E. F. , Kiblitskaya A. A. , Zaikina E. V. , Kurbanova L. Z. , Mindar M. V. 
Published: March 2022

Purpose of the study. Was to analyze antitumor efficacy of the XAV 939 Wnt signaling pathway inhibitor and its combination with 5 fluorouracil in subcutaneous xenografts derived from patients with colorectal cancer.Materials and methods. Antitumor efficacy of the agents and their combination was studied in xenografts derived from patients with colorectal cancer and subcutaneously implanted in immunodeficient Balb/c Nude mice. All animals with tumors were divided into 4 groups (n = 5): group 1 received 5 fluorouracil 25 mg/kg, group 2 – XAV 939 25 mg/kg, group 3–5 fluorouracil and XAV 939 combination at the same dosages, group 4 was control. Criteria for the efficacy of the tested agents and their combination included tumor growth rate and tumor growth inhibition rate (TGI %).Results. The mean volumes of xenografts and tumor growth rate in the group receiving a combination of 5 fluorouracil and XAV 939 were 335.2 ± 40.7 mm3 , being lower than the averages of xenografts in controls – 609.3 ± 69.5 mm3 (p < 0.05). The mean volumes of xenografts in the group receiving 5 fluorouracil monotherapy were 601.9 ± 45.5 mm3 , in the group with the XAV 939 monotherapy – 527.9 ± 258.6 mm3 . The highest TGI (44.99 %) was registered in the group receiving a combination of 5 fluorouracil and XAV 939.Conclusion. The study revealed the ability of combined XAV 939 Wnt signaling pathway inhibitor and 5 fluorouracil to inhibit the growth of subcutaneous xenografts derived from patients with colorectal cancer.
Lung cancers biomarkers
Authors: Kharagezov D. A. , Lazutin Yu. N. , Mirzoyan E. A. , Milakin A. G. , Stateshny O. N. , Leiman I. A. , Iozefi K. D. 
Published: March 2022

More than 1.8 million of new cases of lung cancer (LC) are registered each year worldwide. LC is the leading cause of cancer death in both developing and developed countries, and the 5 years survival rate is as low as 19 %. Many factors explain such unsatisfactory outcomes, including the LC diagnosis at an advanced stage, when the currently available treatments can rarely provide cure. Biomarkers are used to assess the development risks, screening, diagnosis, monitoring, and prognosis, and to personalize the LC treatment. Clinical use of biomarkers is essential for the identification of a high-risk group for screening for LC and differentiating early LC from benign pulmonary lesions. Current trends in the development of LC biomarkers involve the integration of molecular biomarkers with clinical and radiological characteristics using artificial intelligence for the development of imaging biomarkers, and using highly sensitive technologies such as next-generation sequencing for molecular research. LC biomarkers are now at all stages of development, from discovery to clinical trials requiring high-quality clinical validation. Reliable biomarkers are especially needed to differentiate malignant and benign lesions in the lung tissue and to identify those at greatest risk of developing lung cancer. Scientific advances in understanding LC have led to the development of biomarkers that demonstrate sufficient accuracy in clinical validation studies. Promising trends in the development of LC biomarkers include highly sensitive and increasingly accessible NGS and radiomics technologies, along with the use of easily collected biomaterials, which in combination with other tumor characteristics contribute to the development of biomarkers for assessing the LC development risks, diagnosis, monitoring, prognosis and personalized therapy. This review focuses on the development, current application, and future trends in the use of LC biomarkers.
Chronicle and mixture, Vol. XVI, № 2 (1909)
Authors: Baklushinskiy Ivan D. 
Published: March 2022

Prof. Nikolai Mikhailovich Popov at a meeting of the 2nd p. May unanimously elected dean of the Medical Faculty of Novorossiysk University.
From the 1st to the 5th of June of the current year, the second All-Russian congress on pedagogical psychology will take place in St. Petersburg, in the premises of the Salt Town. The organizing committee includes: chairman, academician V. M. Bekhterev, comrades of the chairman A. A. Krogius, A. F. Lazursky, D. M. Levshin and A. P. Nechaev and members D. A. Dril, M. I Konorov, N. E. Rumyantsev, V. V. Uspensky, G. A. Falbork. L. G. Orshansky, Pr.-Assoc. Zhakov, N. K. Kulman, A. I. Zaginyaev, Ya. I. Dushechkin, S. Yu. Blumenau. V. V. Rakhmanov, N. I. Neklyudova, E. S. Dedyulina and others. The members of the congress can be teachers of higher and secondary educational institutions, doctors and persons who have declared themselves to be published works in the field of psychology and school hygiene. All those interested in educational psychology are allowed as guests.
Chronicle of the Society of Neurologists and Psychiatrists at the Imperial Kazan University of February 25, 1909
Authors: Darkshevich Liveriy O. , Pervushin Vsevolod P. 
Published: March 2022

Presided over by prof. L. O. Darkshevich with the secretary Dr. V. P. Pervushin. Actions were present. members: prof. V. P. Osipov, N. A. Mislavsky, I. M. Dogel, V. F. Orlovsky, I. A. Chuevsky; Drs. N. A. Donskov, A. V. Favorsky I. A. Veselitsky, A. S. Segel, F. Ya. Kitaev, V. I. Nikolaev, M. A. Chalusov, G. I. Sorokovikov, A S. Sholomovich. Guests: Drs. N. E. Osokin, M. N. Cheboksarov, N. K. Goryaev, V. K. Voroshilov, S. A. Bolberg, I. I. Tsypkin, Shibkov, Lyubenetsky, Nikolskaya, Nikiforova, Bronnikov and up to 100 people predominantly medical students.
Real member A.V. Favorsky made a report: A case of syringobulbomyelia (with a demonstration of a patient from the clinic of nervous diseases of I.K.U.).
Impacts of petroleum refinery emissions on the health and safety of local residents
Authors: Otitolaiye Victor Olabode , Al-Harethiya Ghadeer Mubarak 
Published: March 2022

The World Health Organization (WHO) estimates that 25% of mortality in developing countries arises from environmental hazards. Over the years, soaring demand for humanity’s essential needs has prompted industrial-scale production and the generation of large quantities of waste. Petroleum refineries generate large quantities of waste which gives rise to health effects such as cancer, eye defects, birth defects, and reproductive defects. Furthermore, the residents living around refineries encounter several hazards arising from operations that generate noise, radiation, chemicals, vibration, dust and toxic pollutant gases. The current research landscape indicates that Petroleum Refinery Emissions or PREs pose significant risks to human health, safety and the environment. Therefore, this paper presents a concise review of the acute and chronic effects of PREs on the health and safety of residents living within the vicinity of petroleum refineries. The reviewed literature revealed that PREs cause various cancers, leukaemia, as well as cardiovascular, respiratory, and reproduction disorders. Hence, numerous approaches to mitigate, eliminate or address the short and long term effects of PREs have been proposed in the literature. The proposed approaches include the bioremediation as well as the monitoring and evaluation of PREs to promptly detect, remediate and eliminate the hazards. However, other measures that could help address the outlined occupational health and environmental safety-related issues will go a long way in mitigating or curbing the socio-economic, environmental, health and safety impacts of PREs and industrial wastes.