bluuebunny/crossref_metadata_2025_split huggingface dataset:
Simultaneous determination of six triterpenoid saponins in beagle dog plasma by UPLC-MS/MS and its application to a pharmacokinetic study after oral administration of the extract of the Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. leaves
Authors: Wang Zhibin , Chang Yaodan , Cao Feng , Yang Chunjuan , Wang Zhenyue , Kuang Haixue 
Published: May 2022

AbstractA rapid and simple ultra-performance liquid chromatography-electrospray ionization-tandem mass spectrometry (UPLC-ESI-MS/MS) method was developed and validated for simultaneous determination of six analytes from the Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. leaves (ESL) in beagle dog plasma for the first time, including 3-O-α-l-rhamnopyranosyl-(1→2)-α-l-arabinopyranoside-29-hydroxy oleanolic acid, 3-O-β-d-glucopyranosyl-(1→2)-α-l-arabinopyranoside-29-hydroxy oleanolic acid, 3-O-β-d-glucopyranosyl-(1→2)-α-l-arabinopyranosyl-30-norlean-12,20 (29) –dien-28-olic acid, ciwujianoside E, guaianin N, and eleutheroside K. The chromatographic separation was performed using an ACQUITY UPLC BEH C18 column (2.1 × 100 mm, 1.7 μm) using a gradient elution way with a mobile phase of acetonitrile-water containing 0.1% formic acid. Analytes were detected on a triple-quadrupole mass spectrometer equipped with an electrospray ionization (ESI) source with multiple reaction monitoring (MRM) mode. Calibration curves were all linear (r ≥ 0.9933) over the concentration range. The mean extraction recoveries and matrix effect of analytes and I.S. were ranged from 80.26% to 98.32% and from 91.27% to 111.67%, respectively. The intra-day and inter-day precision were ranged from 2.20% to 14.81%, and the accuracy range was 1.60–14.60%. The analytical method was successfully applied for the pharmacokinetic characteristics of the six analytes in beagle plasma after oral administration of ESL extracts. The T1/2 of six analytes was more than 3.09 ± 0.78 h.
Analysis of nature based flood management in the Tisza River Valley, Hungary
Authors: Murányi Gábor , Koncsos László 
Published: May 2022

Abstract
The floodplains of the Tisza River, stretching across the eastern part of Hungary, are often affected by riverine and inland excess water flooding and draught. This paper investigates a possible solution to this problem utilizing the water retention capabilities of old floodplains. In this study, the effect of the position of the inlet structures of a floodplain, near Csongrád town, was examined with HEC-RAS 1D-2D coupled model. Based on the results, the rules of the deep floodplain selection were determined. On the extended model, the possibilities of a deep floodplain storage area chain have been explored. According to the estimate, more than 2.36 km3 potential storage capacity is available along the Hungarian section of the Tisza River.
Designing street furniture: A protocol to enhance the quality of life in urban spaces
Authors: Ben Dhaou Ons , Vasváry-Nádor Norbert , Gall Anthony 
Published: May 2022

Abstract
In order to develop and enhance the quality of life in Tunisian urban spaces, the integration of street furniture became a new challenge for urban designers to use new methods and techniques to combine functionality and aesthetics into their design. The main objective of this paper is to focus on the analysis of the street furniture user’s needs in urban spaces to understand and discuss the requirements that should be considered while designing.
Using nature-based solutions to support urban regeneration: A conceptual study
Authors: He Qingchang , Reith Andras 
Published: May 2022

Abstract
Nature-based solutions use a holistic viewpoint to address social challenges while providing environmental, social and economic benefits simultaneously. The Victoria Quay is a historical space with complex social and environmental issues. This study uses an investigation-oriented method to explore the re-planning strategies. The environmental problems are addressed by extending the green infrastructure into the site to recover the ecological corridor and alleviate flooding risks. The originally single land-use type is changed, and several historical buildings are transformed into landmarks to improve the connection with city center by linking the ‘golden route’. All the proposed measures tried to reactivate the various relationships rather than merely renew the Victoria Quay.
Clinical Case of Sarcoidosis as a Rare Cause of Lymphadenopathy in Preschool Child
Authors: Khorosheva Elena Y. , Khramova Elena B. , Gorohova Natalya E. , Mashkina Natalya A. , Kozlov Nikolay V. , Kuzmicheva Ksenia P. 
Published: May 2022

Background. Assignment of causes of generalized lymphadenopathy causes as a symptom of various diseases is still challenging. In case of no infectious causes, the morphological study is necessary also to exclude sarcoidosis, rare for young children immunemediated systemic disease with intermediate prognosis.Clinical case description. 4 years girl was diagnosed sarcoidosis with typical lesions of intrathoracic lymph nodes and lungs along with signs of generalized lymphadenopathy. Molecular genetic testing has revealed pathogenic variant in the TNFRSF13B gene that was previously described in adult patients with general variable immunodeficiency and pulmonary sarcoidosis. Catamnestic follow-up data on this patient are presented for 3 years. There were no relapses without immunosuppressive therapy.Conclusion. Sarcoidosis was described as the cause of generalized lymphadenopathy in preschool child. Following the federal guidelines has helped to adjust diagnosis tactics, to establish diagnosis, and to choose treatment.
Çoban Çantası, Capsella bursa-pastoris bitki ekstraktının dişi sıçanlarda cinsiyet hormonları üzerine etkileri
Authors: TUNCEL Fatmanur , COŞKUN Nuri Cenk 
Published: May 2022

Amaç: Capsella bursa-pastoris, jinekolojik hastalıkların ve semptomlarının tedavisi için yıllardır insanlar tarafından kullanıldığı bilinen bir bitki türüdür. Bu çalışmanın amacı dişi sıçanlara Capsella bursa-pastoris bitki ekstraktının oral gavaj ile enteral yolla verilmesi sonucu sıçanlarda meydana gelen hormonal değişiklikleri plazma düzeyinde inceleyerek bu bitkinin cinsiyet hormonları üzerine etkilerini araştırmaktır.
Yöntem: Capsella bursa-pastoris bitkisinin sulu ve hidroalkolik ekstraktı oral gavajla 1 haftalık süre boyunca üç ayrı gruba verilmiştir. Uygulamada, Capsella bursa-pastoris’in sulu ekstraktını alan sıçan grubuna 1.07 g/100g, 2.68 g/100g, 5.35 g/100g; hidroalkolik ekstraktını alan sıçan grubuna 1.05 g/100g, 2.63 g/100g, 5.25 g/100g dozlar uygulanmıştır. Sonrasında Capsella bursa-pastoris ekstraktının cinsiyet hormonları üzerinde etkisini anlamak için sıçanlardan alınan kan örnekleri biyokimyasal immünokemilüminesans yöntemiyle analiz edilmiştir.
Bulgular: Kan analizleri değerlendirildiğinde, Capsella bursa-pastoris’in her iki ekstraktının uygulandığı sıçanlarda; östrojen ölçümü sonuçları bakımından gruplar arasında anlamlı bir farklılık bulunmamıştır (p=0.400). Progesteron ölçümü sonuçları değerlendirildiğinde ise benzer şekilde Capsella bursa-pastoris’in plazma progesteron düzeylerine etkisi bakımından gruplar arasında anlamlı bir farklılık bulunmamıştır (p=0.184).
Sonuç: Sonuç olarak çalışmamızdan elde ettiğimiz veriler bize bitkinin sulu ve hidroalkolik ekstraktının kullandığımız dozlarda özellikle östrojen ve progesteron hormonlarının üzerinde anlamlı bir etkisinin olmadığını göstermiştir. Bu sonuçlar, bitkinin ileri sürülen tedavi edici etkilerinin, östrojen ve progesteron hormon düzeyleri üzerine etkileri ile ilgili olmayıp bitkiye atfedilen diğer etkileri üzerinden olabileceğini düşündürmektedir.
Evaluation of pneumothorax in the neonatal intensive care unit
Authors: MELEKOĞLU Nuriye , SİNANOĞLU Muhammed Selçuk , BERK Erhan 
Published: May 2022

Objective: Pneumothorax is one of the most common pulmonary air leak syndromes and appears more often in the newborn period than at any other time of life. In this study, we aimed to determine and compare the demographic characteristics, clinical courses and outcomes of newborns with primary and secondary pneumothorax.
Methods: In this single-centre retrospective study, maternal and neonatal data were collected from medical records at Turgut Ozal University Hospital between January 2020 to July 2021.
Results: Twenty-nine newborns diagnosed with pneumothorax, and of these, 16 were male (55.2%), 19 (65.5%) were born by cesarean section, and six (20.7%) were premature. The mean gestational age was 37.5±2.6 weeks, and birth weight was 3063.4±53 grams. The median age at diagnosis was 5 h (1-96), and the mean hospital stay was 9.55±4.38 days. The mean drainage time was 4.1±2.13 days. 13 (44.8%) neonates were classified as primary, while 16 patients (55.2%) had an underlying pulmonary disease or predisposing factor. Our study showed a statistically significant difference between groups regarding Apgar score 5th min and SNAP-II scores (p < 0.05). The occurence of pneumothorax was significantly earlier in the primary group (p < 0.05). Our study revealed significantly longer total oxygen, continuous positive airway pressure and mechanical ventilation durations in the secondary pneumothorax group (p
Hubungan Indeks Massa Tubuh, Kekuatan Otot Lengan, dan Kekuatan Otot Tungkai dengan Kecepatan Renang Gaya Bebas Pada Atlet Renang Vyati Swimming Klub Kota Batu
Authors: El Muniri Ali Bisri , Sulistyorini Sulistyorini , Supriatna Supriatna 
Published: May 2022

Abstract: This study aims to find the relationship between several variables in the study, including the relationship between body mass index, arm muscle strength, and leg muscle strength with freestyle swimming speed in athletes. This study uses a correlational research design, this method serves to find and find the tendency of a relationship between variables, how strong the relationship between variables in the study. The subjects in the study were 15 swimming students who were members of the Vyati Swimming Club in Batu City. This research was conducted for 2 weeks with every week used for research data collection. The instrument in this test uses a measurement test on each variable in the study. From the results obtained 0,026 less than 0,05. from the results of the analysis there is a relationship that is quite influential on each variable.
Abstrak: Penelitian ini bertujuan untuk mencari keterhubungan antara beberapa variabel dalam penelitian, meliputi hubungan indeks massa tubuh, kekuatan otot lengan, dan kekuatan otot tungkai dengan kecepatan renang gaya bebas pada atlet. Penelitian ini menggunakan rancangan penelitian korelasional, metode ini berfungsi untuk mencari dan menemukan kecenderungan suatu keterhubungan antar variabel, seberapa kuat hubungannya antar variabel dalam penelitian tersebut. Subjek dalam penelitian ini berjumlah 15 peserta didik renang yang tergabung dalam Vyati Swimming Club Kota Batu. Penelitian ini dilakukan selama 2 minggu dengan setiap minggu digunakan untuk pengambilan data penelitian. Instrumen dalam tes ini menggunakan tes pengukuran pada setiap variabel dalam penelitian. Dari hasil uji korelasi ganda diperoleh 0,026 kurang dari 0,05. Dari hasil analisis tersebut terdapat hubungan yang cukup berpengaruh pada setiap variabel.
Methodological features selection and implementation of frames in authentic videos with hybrid academic teaching a foreign language. Part II
Authors: Крылова О.В. 
Published: May 2022

Представлена типологию фреймов, применимых к курсам иностранного (английского) языка для инженерных профилей, демонстрирует примеры фреймов, используемых для моделирования учебных текстов и видеоматериалов внутри и за пределами класса. Показано, что при гибридном обучении эвристическому чтению и переводу на иностранных языках использование аудиовизуальных материалов способствует оптимизации процессов преподавания и обучения. Лингвистические, дискурсивные и технические рамки используются преподавателем для объяснения и реализации коммуникативных намерений с учетом межкультурного разнообразия с точки зрения исследовательского, социально-исторического и этико-философского развития обучающихся. Сделан вывод о необходимости создания инженерного многокадрового словаря и видеоуроков для будущих инженерных специалистов.
Present a typology of frames applicable to Foreign (English) Language Courses for Engineering Profi les, and demonstrates some frames in use for modeling educational texts and video materials inside and outside the classroom. In the second part of the article, it is shown that in hybrid teaching of heuristic reading and translation in foreign languages, the use of audiovisual materials contributes to the optimization of the teaching/learning process through the formation of professional competence in the nearest future. Linguistic, discursive and technical frames are used by the teacher to explain and implement communicative intentions taking into account intercultural diversity in terms of research, socio-historical and ethical-philosophical development. It is concluded that it is necessary to create an engineering multi-frame dictionary and video tutorials for future engineering specialists.
Therapeutic remission alcoholism in the indigenous population Chukotka and its dependence on personal patient characteristics
Authors: Литвякова О.С. 
Published: May 2022

Описан ход исследования, проведенного на Чукотке в период с 2014 по 2018 год, связанного с наблюдением прохождения пациентами краткосрочной программы реабилитации по методу Я. Маршака. Показана взаимосвязь продолжительности терапевтической ремиссии у больных алкоголизмом представителей коренного населения Чукотки и их личностных характеристик. Установлено, что терапевтическая ремиссия наиболее продолжительна (4 года) при низких показателях потребности в поиске острых ощущений, волевой саморегуляции, настойчивости, локуса контроля-Я. Выявлены индивидуально-психологические характеристики пациента, влияющие на продолжительность ремиссии.
The course of a study conducted in Chukotka in the period from 2014 to 2018, related to the observation of patients undergoing a short-term rehabilitation program using the method of Ya. Marshak, is described. The relationship between the duration of therapeutic remission in alcoholism patients of the indigenous population of Chukotka and their personal characteristics is shown. It was found that therapeutic remission is the longest (4 years) with low indicators of the need to search for thrills, volitional self-regulation, perseverance, locus of control-I. The individual psychological characteristics of the patient aff ecting the duration of remission were revealed.
Semantics and grammar polyfunctional units (on the example of the lexeme "everything"): linguodidactic aspect
Authors: Мареева Ю.А. 
Published: May 2022

Проанализированы лексико-семантические варианты полифункциональной лексемы «всё», выступающей в роли наречия и частицы, рассмотрены основные случаи ее употребления. Представлен фрагмент системы упражнений на презентацию и активизацию данной лексической единицы в устной и письменной речи инофонов. Обоснована необходимость изучения полифункциональных единиц, играющих важную роль в устном дискурсе, в курсе русского языка как иностранного. Показана роль системы упражнений и заданий, построенной в русле функционально-коммуникативной грамматики, позволяющей поэтапно сформировать у иностранных обучающихся необходимые языковые навыки употребления лексемы «всё» как в рецептивных, так и в продуктивных видах речевой деятельности.
The article deals with lexico-semantic variants of polyfunctional lexem “vsyo” (‘all’) which can play the role of an adverb or a particle; the basic forms of its usage are analyzed and the part of system of exercises on presentation and activization of this lexical unit in oral and written communication of foreign students is presented. We explain the necessity of studying of polyfunctional units in the course of Russian as a foreign language as far as along with intonation they play important role in oral discourse. The system of tasks and exercises implemented in the frame of functional-communicative grammar allows gradually build to foreign students the necessary language skills of using of the lexem “vsyo” in speech reception as well as in speech production. The tasks consider semantic, stylistic characteristics of lexem “vsyo”, its paradigmatic and syntagmatic features.
Day of Slavic Writing and culture in the system of work for civil and patriotic and spiritual and moral education of students
Authors: Бакула В.Б. , Коренева А.В. , Саватеева О.В. , Шевченко Н.А. 
Published: May 2022

Рассматриваются вопросы организации воспитательной работы в Мурманском арктическом государственном университете. Характеризуются возможности проведения Дня славянской письменности и культуры в формировании духовно-нравственных ценностей и гражданской культуры студентов Мурманской области. Описываются задачи, содержание и формы проведения Кирилло-Мефодиевской недели преподавателями университета.
The issues of the organization of educational work at the Murmansk Arctic State University are considered. The possibilities of holding the Day of Slavic Writing and Culture in the formation of spiritual and moral values and civic culture of students of the Murmansk region are characterized. The tasks, content and forms of the Cyril and Methodius Week by university teachers are described.
Interaction of the Pedagogical University with educational organizations preschool and elementary general education for the training of specialists to the use of ... modern information technologies
Authors: Демина Н.В. , Сабанова Л.В. 
Published: May 2022

. Рассмотрена организация взаимодействия педагогического вуза с образовательными учреждениями с целью изучения потребностей в подготовке выпускников, обладающих компетенциями по использованию современного интерактивного оборудования в своей профессиональной деятельности. Описана работа по оказанию методической поддержки педагогам различных образовательных организаций, ориентированная на преодоление у них дефицита ИКТ-компетенций, необходимых для решения профессиональных задач.
The article considers the organization of interaction between a pedagogical university and educational institutions in order to study the needs for training graduates who have the necessary competencies to use modern interactive equipment in their professional activities. The paper describes the work on providing methodological support to teachers of various educational organizations, focused on overcoming their lack of ICT competencies necessary for solving professional tasks.
Development of volitional qualities in the classroom extracurricular activities as a factor the formation of the personality of adolescents
Authors: Пчелинцева Д.Г. 
Published: May 2022

Представлены результаты опытно-экспериментальной работы, направленной на выявление условий развития волевых качеств у подростков на занятиях внеурочной деятельности по иностранному языку. Рассмотрено содержание авторской психолого-педагогической программы обучения. Выделены задачи образовательной деятельности: формирование у подростков устойчивого поведения, добросовестного отношения к труду и учению, повышение их культурного уровня. Приведены данные анализа результатов оценки уровня развития волевых качеств у подростков в МБОУ «Школа 28» города Рязани.
The article deals with the results of a pilot experimentation which was aimed at the development of volitional qualities among adolescents in in extracurricular activities in a foreign language. It was reviewed the content of the author’s psychological and pedagogical program. The objectives of educational activities are: the development of sustainable behavior in adolescents, a conscientious attitude towards work and education, and the raising of their cultural level. The data of the analysis of an experimental study assessing the level of development of volitional qualities among adolescents of the Municipal Budget General Educational Institution «School 28» in Ryazan are given.
From the history of the Russian piano pedagogy. In the class of V.V. Sheet
Authors: Захаренкова Е.И. , Сыюй Ц. 
Published: May 2022

Статья посвящена творческому наследию выдающегося педагога гнесинской школы Валерии Владимировны Листовой. Рассматриваются нестандартные, на практике доказавшие свою высокую эффективность приемы педагогической работы В.В. Листовой, направленные на формирование у обучающихся профессиональных технических навыков в начальный период обучения, обеспечивающих все последующие этапы творческого роста пианистов – исполнителей и педагогов.
The article is devoted to the creative heritage of the outstanding teacher of the Gnessin School Valeria Vladimirovna Listova. The article considers non-standard methods of V.V. Listova’s pedagogical work, which have proven their high eff ectiveness in practice, aimed at the formation of professional technical skills among students in the initial period of training, providing all subsequent stages of the creative growth of pianists, both performers and teachers.
Results of experimental work on the training of military cadets universities of the Russian Guard to professional communication in multiethnic space of Russia
Authors: Поляков О.А. 
Published: May 2022

В статье рассмотрена проблема формирования готовности у курсантов военных вузов войск национальной гвардии Российской Федерации к профессиональной коммуникации в полиэтническом пространстве России. Раскрыты сущностные и параметральные характеристики готовности к профессиональной коммуникации, обозначен диагностический инструментарий изучаемого личностного образования. Описаны педагогические условия, способствующие эффективному формированию данного феномена. Представлены результаты опытно-экспериментальной работы, проводимой на базе Пермского и Санкт-Петербургского военных институтов войск национальной гвардии Российской Федерации.
The article deals with the problem of formation of readiness among cadets of military universities of the troops of the national guard of the Russian Federation for professional communication in the multi-ethnic space of the Russian Federation. The essential and parametric characteristics of readiness for professional communication in the multi-ethnic space of the Russian Federation are revealed, the diagnostic tools of the studied personal education are indicated. Pedagogical conditions that contribute to the eff ective formation of this phenomenon are described. The results of experimental work carried out on the basis of the Perm and Saint Petersburg Military Institutes of the National Guard Troops of the Russian Federation are presented.
The Aftermath of 21st Century Sharia Implementation in Northern Nigeria
Authors: Duku Muhammad 
Published: May 2022

Enforcement of Sharia legal system is a duty bound over every Muslim (Male or Female) on their day to day life and activities. The objective of this paper is to examine the consequences after the implementation of Shari’ah law in 21st Century in Northern part of Nigeria. Therefore, this study addresses the major area of negation and setback in the implementation of Shari’ah law in 21st Century in Northern Nigeria. The study posit out that inconsistence of Nigerian constitution with Shari’ah law, capital offence punishable by Shari’ah law, Hisbah institution, lack of qualified and experts judges, political problem and many others are the setback encountered by means of Shari’ah implementation in Northern Nigeria. Conclusively, the study concludes that 21st Century Shari’ah implementation in Northern Nigeria faced with many challenges.