bluuebunny/crossref_metadata_2025_split huggingface dataset:
Circular RNAs expression profiles and bioinformatics analysis in bronchopulmonary dysplasia
Authors: Lun Yu , Hu Junlong , Zuming Yang 
Published: December 2022

AbstractBackgroundBronchopulmonary dysplasia (BPD) has long been considered the most challenging chronic lung disease for neonatologists and researchers due to its complex pathological mechanisms and difficulty in prediction. Growing evidence indicates that BPD is associated with the dysregulation of circular RNAs (circRNAs). Therefore, we aimed to explore the expression profiles of circRNAs and investigate the underlying molecular network associated with BPD.MethodsPeripheral blood was collected from very‐low‐birth‐weight (VLBW) infants at 5–8 days of life to extract PBMCs. Microarray analysis and qRT‐PCR tests were performed to determine the differentially expressed circRNAs (DEcircRNAs) between BPD and non‐BPD VLBW infants. Simultaneous analysis of GSE32472 was conducted to obtain differentially expressed mRNAs (DEmRNA) from BPD infants. The miRNAs were predicted by DEcircRNAs and DEmRNAs of upregulated, respectively, and then screened for overlapping ones. GO and KEGG analysis was performed following construction of the competing endogenous RNA regulatory network (ceRNA) for further investigation.ResultsA total of 65 circRNAs (52 upregulated and 13 downregulated) were identified as DEcircRNAs between the two groups (FC >2.0 and p.adj <0.05). As a result, the ceRNA network was constructed based on three upregulated DEcircRNAs validated by qRT‐PCR (hsa_circ_0007054, hsa_circ_0057950, and hsa_circ_0120151). Bioinformatics analysis indicated these DEcircRNAs participated in response to stimulus, IL‐1 receptor activation, neutrophil activation, and metabolic pathways.ConclusionsIn VLBW infants with a high risk for developing BPD, the circRNA expression profiles in PBMCs were significantly altered in the early post‐birth period, suggesting immune dysregulation caused by infection and inflammatory response already existed.
Impact of age‐dependent red blood cell parameters on α‐globin gene genotyping in children
Authors: Nissen Peter H. , Narvestad‐Bøttger Helene , Kristensen Helle Pilgaard , Winther‐Larsen Anne 
Published: December 2022

AbstractWhen screening for α‐thalassemia in children, adult cut‐offs for mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) are generally applied to guide genetic evaluation. However, the normal ranges for MCV and MCH are lower in children than in adults, so we hypothesized that using age‐matched cut‐offs could lead to a more rational diagnostic strategy. The aim of this study was to evaluate if age‐matched cut‐offs could be applied advantageously. Data on children referred to a hemoglobin fractionation at the Department of Clinical Biochemistry, Aarhus University Hospital between 2016–2021 were identified in the laboratory information system. α‐globin gene (HBA1/HBA2) genotyping was performed using multiplex gap‐polymerase chain reaction. A total of 387 children were identified. HBA1/HBA2‐genotyping was performed in 207 children (53%), and α‐thalassemia was diagnosed in 47 children (23%) with −α3.7/αα being the predominant genotype (13%). We found that 23 children had MCV and MCH levels in the normal age‐matched range, and two of these children (9%) were α+ thalassemia carriers with three functional α‐globin genes. Using age‐specific cut‐off levels resulted in a reduction of 23 (11%) genotypes performed. In conclusion, applying age‐matched cut‐offs for MCV and MCH when screening children for α‐thalassemia lead to 11% fewer genotypes performed while 9% carriers of α+ thalassemia (of the medically innocuous genotype −α3.7/αα) would have been overlooked.
A New Class of Single‐Material, Non‐Reciprocal Microactuators
Authors: Maslen Charlie , Gholamipour‐Shirazi Azarmidokht , Butler Matthew D. , Kropacek Jindrich , Rehor Ivan , Montenegro‐Johnson Thomas 
Published: December 2022

AbstractA crucial component in designing soft actuating structures with controllable shape changes is programming internal, mismatching stresses. In this work, a new paradigm for achieving anisotropic dynamics between isotropic end‐states—yielding a non‐reciprocal shrinking/swelling response over a full actuation cycle—in a microscale actuator made of a single material, purely through microscale design is demonstrated. Anisotropic dynamics is achieved by incorporating micro‐sized pores into certain segments of the structures; by arranging porous and non‐porous segments (specifically, struts) into a 2D hexagonally‐shaped microscopic poly(N‐isopropyl acrylamide) hydrogel particle, the rate of isotropic shrinking/swelling in the structure is locally modulated, generating global anisotropic, non‐reciprocal, dynamics. A simple mathematical model is introduced that reveals the physics that underlies these dynamics. This design has the potential to be used as a foundational tool for inducing non‐reciprocal actuation cycles with a single material structure, and enables new possibilities in producing customized soft actuators and modular anisotropic metamaterials for a range of real‐world applications, such as artificial cilia.
Chemical Bonding in the Catalytic Platform Material Ga1‐xSnxPd2
Authors: Ormeci Alim , Gaudry Emilie , Armbrüster Marc , Grin Yuri 
Published: December 2022

AbstractThe underlying reasons for the catalytic activity of Ga1‐xSnxPd2 (0 ≤ x ≤ 1) in the semi‐hydrogenation of acetylene are analyzed considering electronic structure and chemical bonding. Analysis of the chemical bonding shows pronounced charge transfer from the p elements to palladium and an unusual appearance of the Pd core basins at the surface of the QTAIM (quantum theory of atoms in molecules) atoms. The charge transfer supports the formation of the negatively charged palladium catalytic centers. Gallium‐only‐coordinated palladium atoms reveal a smaller effective charge in comparison with palladium species having tin in their coordination sphere. Within the empirical tight‐binding approach, different influence of the E‐Pd distances on the calculation matrix for the energy eigenvalues and the electronic density of states (DOS) leads to an S‐like shape of the plot of the energy position of the 4d band center of gravity versus substitution level x. The latter correlates strongly with the catalytic activity and with the varying charge transfer to palladium. The optimal value of negative palladium charge and the closest position of Pd d‐states gravity center towards the Fermi level correlates well with the catalytically most active composition x. Combination of all features of the chemical bonding and electronic structure allows more insight into the intrinsic reasons for the catalytic activity variation in the platform material Ga1‐xSnxPd2 (0 ≤ x ≤ 1).
A conceptual framework for a value‐based sustainability balanced scorecard
Authors: Trisyulianti Erlin , Prihartono Budhi , Andriani Made , Suryadi Kadarsah 
Published: December 2022

AbstractSustainability balanced scorecard (SBSC) is a management system that can translate strategy into the company's operations. However, based on previous research, a gap states that using SBSC gives birth to many performance indicators. Therefore, we need a framework that can formulate performance indicators to be more proportional to using company resources. For this reason, this research proposes a value framework adopted from six business process values. These six values ​​are efficiency, quality, agility, integration, compliance, and networking. This study aims to prove that these six values ​​can be used as SBSC values. So that will be obtained A Conceptual Framework for a Value‐Based Sustainability Balanced Scorecard. The methodology explored three state‐owned plantation enterprise in Indonesia and analyzed data using qualitative research coding. The result shows that there are 11 criteria for efficiency, 11 for quality, seven for agility, 12 for compliance, eight for integration, and nine for networking. These criteria have a 100% validation level where the value criteria are found in each company. The performance indicator criteria have been assessed based on the level of relevance test from managers who say that it is almost 100% important and very important. The criteria that have been grouped against these values ​​have proven that the six values ​​can be used to direct managers in formulating company performance indicators so that the established performance indicators are expected to allocate resources proportionally.
Carbon‐SO3Na Catalysed Synthesis of Glycerol Carbonate via Transesterification of Glycerol and Dimethyl Carbonate
Authors: Sandhya Rani Gundabathini , Jyotsna Adigopula , Prabhavathi Devi Bethala L. A. 
Published: December 2022

AbstractGlycerol, a major by‐product from biodiesel industry valorized into glycerol carbonate (GC) employing heterogeneous carbon‐based sulfated sodium (carbon‐SO3Na) catalyst derived from glycerol. Investigations have been conducted to study the influence of reaction parameters such as catalyst dosage, DMC/glycerol molar ratio, reaction temperature and reaction time for the production of GC in high yield with high selectivity from glycerol and dimethyl carbonate (DMC) via transesterification process. Under optimized conditions the maximum GC yield (>99 %) with 100 % selectivity was observed with catalyst dose of 1.5 wt.% (of glycerol), DMC/glycerol molar ratio of 3 : 1, reaction temperature of 80 °C in 3 h of reaction period. Further, the catalyst was easily recovered from reaction mixture and reused without any pre‐treatment. The catalyst maintained its crystalline nature with remarkable performance even after 5 cycles of reaction without any deactivation and leaching. The main advantage of the adopted carbon‐SO3Na catalyzed protocol for the synthesis of GC is environmentally benign due to its high yield and selectivity under mild reaction conditions. Thus, the carbon‐SO3Na catalyst has a wide utility as a potential heterogeneous solid base catalyst for several organic transformations.
The interplay between learner autonomy and indirect written corrective feedback in EFL writing
Authors: Pham Luan Nhu 
Published: December 2022

AbstractThis study investigated the relationship between learner autonomy (LA) and indirect written corrective feedback (IWCF) in an EFL writing classroom in Vietnam. Forty‐one intermediate EFL learners from a class of a foundation writing course volunteered to participate in the study. During the course, the teacher provided IWCF in response to the learners' errors and encouraged them to revise, edit, and correct those errors using a set of procedures. The study revealed that the learners with higher autonomy were more successful in correcting errors and in producing error‐free modified pieces of writing than those with lower autonomy. This indicated that there could be a considerable mediating effect of LA on the efficacy of IWCF. It was also found that there seemed to be positive changes in the awareness and learning practices of the learners towards a more autonomous learning at the end of the course. The study suggests that IWCF can be very effective in an autonomy‐supportive learning environment and that IWCF could help EFL learners to be more autonomous in language learning. Various implications are also discussed.
Institutional determinants of ownership stake in cross‐border acquisitions in Africa: The moderating role of geographic distance
Authors: Galdino Katia M. , Ellis Kimberly M. , Lamont Bruce T. , Ariño Africa 
Published: December 2022

AbstractWe look at how emerging markets' institutional features affect ownership stake in cross‐border acquisitions (CBAs) within Africa. Particularly, we show that the presence of shared colonial history between the home and host country and the extent of fractionalization distance and formal institutional distance influence the acquiring firm's decision regarding its ownership stake in the target. Moreover, we show that geographic distance between the home and host country, by augmenting uncertainty faced by acquiring firms, moderates the relationship between these institutional features and ownership stake. We test our hypotheses in a sample of 341 intra‐Africa CBAs from 2001 to 2016. Generally, we find that greater ex ante uncertainty and ex post costs increase ownership stake. Specifically, greater geographic distance strengthens the positive relationship between shared colonial history and ownership stake and reverses the negative relationship between formal institutional distance and ownership stake. As for fractionalization distance, the relationship is more nuanced and needs to be further studied. We contribute to advance research on south–south CBAs in general, particularly within Africa, as well as to extend hostage theory in foreign market entry strategies in and from emerging markets.
Survey of wild boar hunter interactions with pig farming in central Europe
Authors: Jánoska Ferenc , Nagy Eszter , Tari Tamás , Nagy Rebeka Ráhel , Halász Tibor , Varga Gyula , Kovács Melinda , Kemenszky Péter , Nagy Gábor , Csivincsik Ágnes 
Published: December 2022

AbstractAfrican swine fever (ASF) is a fatal animal disease without zoonotic potential but greatly impacts human well‐being, especially in the most vulnerable human communities. In Europe, ASF concerns mostly the wildlife domain of health. The main vector of the disease is confirmed to be the wild boar, though long‐distance jumps of the infection are due to anthropogenic effects. This study aimed to evaluate the potential role of hunting assistant personnel (beaters and carcass handlers) in ASF spread in Hungary. Based on a personal interview survey, we attempted to identify the epidemiological risk caused by hunting activities and the hunting personnel. The interviews with 58 hunting workers confirmed that an extent backyard pig sector (13 pig farmers) and pork production system (31 pork producers) existed within the study region out of the authorities’ sight. Two pig farmers did not wear special working clothes for pig caring, seven pork producers disposed of slaughter offal in the settlements periphery, and six persons regularly contacted distant pig farms. The revealed knowledge, attitude, and practice of the questioned pig farmers suggested that this sector would be very vulnerable in an epidemic situation; moreover, backyard farms would cause a great risk for wildboar populations. Considering that the study region is the third poorest region of Hungary, these findings called attention to the high epidemiologic risk of socioeconomic inequality between different regions within the European Union.
Moisture, organic matter, and large particle correction for accurate Pb portable X‐ray fluorescence assessment in urban soils
Authors: Walser Sandra L. , Sirkovich Eric C. , Richardson Justin B. , McStay Ainsley E. , Perdrial Nicolas 
Published: December 2022

AbstractThe need for accurate quantification of lead concentrations in urban centers around the world is turning attention towards rapid methods for contamination assessment. Portable X‐ray Fluorescence (pXRF) has been recognized as a more accessible alternative to traditional digestion methods. This study was conducted to produce measurement corrections for in‐situ pXRF measurements conducted on field soils under varying conditions of moisture, organic matter (OM) content, and particle size heterogeneity. Urban forest soils were analyzed for Pb under increasing soil moisture, OM, and coarse fraction contents with two different pXRF and the results were compared to reverse aqua regia digestions. While both instruments showed a strong correlation despite using different calibration methods, correction of pXRF data to digestion values improved accuracy but potentially underestimated Pb concentrations. We propose an empirical correction equation derived from the regression of variance between theoretical and observed concentrations to correct for moisture effects. OM and particle size heterogeneity did not produce a significant effect on Pb measurement and did not warrant correction. Our study confirms other work showing that pXRF provides an accurate and precise alternative to traditional digestion methods for Pb screening, provided that moisture is corrected.
Intravascular papillary hemangioendothelioma disguised as a peripheral sheath tumor of median nerve at the wrist: a case report and literature review
Authors: Shah Vrajesh J. , Sung Kerry , Goodwill Vanessa , Huang Brady K. , Abrams Reid 
Published: December 2022

Abstract

Background
Intravascular papillary hemangioendothelioma (IVPH) is a benign lesion previously reported in the nasal cavity, neck, upper extremities, and breast. Diagnosis with cross-sectional imaging can prove difficult, with histopathological examination necessary for diagnosis. IVPH resulting in carpal tunnel symptoms is quite rare.

Case presentation
We report the case of a 37-year-old woman who presented with a radial, volar right wrist mass enlarging over the span of 5 years. She noted numbness and tingling in her wrist and thumb, exacerbated by minor accidental collisions and wrist hyperextension. There was no antecedent trauma. On examination, a mildly tender, mobile mass was evident at the volar aspect of the right wrist. Magnetic resonance imaging (MRI) with contrast demonstrated a lobulated, predominantly T2 hyperintense, heterogeneously enhancing mass thought to be a peripheral nerve sheath tumor. The patient elected for surgical excision of the mass, and the histopathological examination showed organizing thrombi with prominent papillary endothelial hyperplasia. At the 2-month follow-up, the patient had full range of motion of her fingers and wrist, with subjectively normal sensation in the distribution of the median nerve.

Conclusion
Carpal tunnel syndrome, in exceedingly rare occasions, can result from an IVPH. MRI findings may be confused with more common entities. Histopathological confirmation remains necessary for conclusive diagnosis.
Effects of esters’ cetylated fatty acids taping for chronic neck pain with mobility deficit in patients with breast cancer
Authors: Izzo Rosanna , Rossato Mariasole , Tarantino Germano , Mascolo Nicola , Puleio Mauro 
Published: December 2022

Abstract

Purpose
To evaluate the effects of a protocol treatment based on inelastic adhesive tape with cetylated fatty acids (CFAs) esters in breast cancer survivors with chronic neck pain.

Methods
In this observational study, patients have been visited for chronic neck pain using numeric rating scale (NRS) for pain assessment, Neck Disability Index (NDI) for disability caused by neck pain, and range of movement (ROM) measures for cervical mobility. Scales have been performed at T0, after 15 days of treatment (T1) and successively after 15 days of stop treatment (T2). Patients have been treated with an inelastic adhesive tape with CFA esters (Cetilar® Tape, Pharmanutra Spa, Italy) positioned, 8 h/day for 15 days, on specific anatomic sites (upper trapezius, paravertebral cervical muscles, sub-occipitals, and/or levator scapulae muscles).

Results
Forty-five patients were included in the study. A statistically significant reduction in pain has been reported from T0 to T1 and maintained at T2 (p < 0.05); a statistically significant improvement in the mobility of the cervical spine, as evidenced by ROMs, and in disability, as resulted by Neck Disability Index, have been reported from T0 to T1 and maintained at T2; moreover, ROM at T0 correlates inversely and statistically significantly with NRS and all NDI variables at T0, similarly at T1 and T2 (p < 0.001).

Conclusions
CFA ester taping is a simple, effective, and side-effect-free treatment in order to reduce pain and improve cervical mobility in breast cancer survivors with chronic neck pain.
An Algorithmic Assessment of Parole Decisions
Authors: Laqueur Hannah S. , Copus Ryan W. 
Published: December 2022

AbstractObjectivesParole is an important mechanism for alleviating the extraordinary social and financial costs of mass incarceration. Yet parole boards can also present a major obstacle, denying parole to low-risk inmates who could safely be released from prison. We evaluate a major parole institution, the New York State Parole Board, quantifying the costs of non-risk-based decision-making.MethodsUsing ensemble machine Learning, we predict any arrest and any violent felony arrest within three years to generate criminal risk predictions for individuals released on parole in New York from 2012–2015. We quantify the social welfare loss of the Board’s non-risked-base decisions by rank ordering inmates by their predicted risk and estimating the crime rates that could have been achieved with counterfactual, risk-based release decisions. We also estimate the release rates that could have been achieved holding arrest rates constant. We attend to the “selective labels” problem in several ways, including by testing the validity of the algorithm for individuals who were denied parole but later released after the expiration of their sentence.ResultsWe conservatively estimate that the Board could have more than doubled the release rate without increasing the total or violent felony arrest rate, and that they could have achieved these gains while simultaneously eliminating racial disparities in release rates.ConclusionsThis study demonstrates the utility of algorithms for evaluating criminal justice decision-making. Our analyses suggest that many individuals are being denied parole and incarcerated past their minimum sentence despite being a low risk to public safety.
TubAR: an R Package for Quantifying Tuber Shape and Skin Traits from Images
Authors: Miller Michael D. , Schmitz Carley Cari A. , Figueroa Rachel A. , Feldman Max J. , Haagenson Darrin , Shannon Laura M. 
Published: December 2022

AbstractPotato market value is heavily affected by tuber quality traits such as shape, color, and skinning. Despite this, potato breeders often rely on subjective scales that fail to precisely define phenotypes. Individual human evaluators and the environments in which ratings are taken can bias visual quality ratings. Collecting quality trait data using machine vision allows for precise measurements that will remain reliable between evaluators and breeding programs. Here we present TubAR (Tuber Analysis in R), an image analysis program designed to collect data for multiple tuber quality traits at low cost to breeders. To assess the efficacy of TubAR in comparison to visual scales, red-skinned potatoes were evaluated using both methods. Broad sense heritability was consistently higher for skinning, roundness, and length to width ratio using TubAR. TubAR collects essential data on fresh market potato breeding populations while maintaining efficiency by measuring multiple traits through one phenotyping protocol.