bluuebunny/crossref_metadata_2025_split huggingface dataset:
Iron Profile in Patients with Type II Diabetes Mellitus in — A study in a Tertiary Care Hospital
Authors: Lagisetty Lavanya 
Published: September 2022

Abstract

Background: The most prevalent metabolic condition, type 2 diabetes mellitus, is characterized by persistent hyperglycemia caused by abnormalities in insulin production, insulin action, or both. Iron, a transitional metal, has been demonstrated to play a key role in the pathophysiology of Type 2 Diabetes Mellitus, with a bidirectional link in which iron influences glucose metabolism, which in turn influences the iron metabolic pathways. The current study aimed to estimate the iron profile in Type 2 diabetes mellitus cases.

Methods: This cross-sectional study was done in the Department of Biochemistry, Prathima Institute of Medical Sciences, Naganoor, Karimnagar. A total of n=100 cases of type II diabetes mellitus were included in the study and age and sex-matched healthy controls were also included in the study. Laboratory investigations included Fasting Blood glucose, Serum ferritin, Total iron-binding capacity, serum iron, and serum transferrin saturation.

Results: The fasting blood glucose was found to be significantly higher in the diabetes mellitus cases. The serum ferritin mean values were 105.32 µgm/dl. In the controls, the range of ferritin levels was 145 µgm/dl. The serum ferritin levels were found to be significantly reduced in the study cases as compared to the controls. Similarly, the total iron-binding capacity (TIBC) of the cases was found to be significantly increased as compared to the controls. The serum transferrin levels were also found to be elevated in the study cases as compared to the controls.

Conclusion: Iron is closely related to the development of diabetes mellitus. Elevated iron and ferritin levels are risk factors for diabetes and can lead to a variety of problems. Conversely in chronic diabetics, there is a tendency to develop iron deficiency anemia and other nutritional deficiency anemias as observed by the results of the current study. As a result, iron profile evaluation can be a valuable output of the expected investigations on diabetes and related problems.
Risk Factors and Predictors of Outcome for Necrotising Fasciitis
Authors: Pandya Jayashree , Ramteke Riya , Waghmare Sudatta 
Published: September 2022

Abstract

Background:Necrotising fasciitis(NF) is one of the most fulminant infection of skin and soft tissue. It is a fatal rapidly progressing disease causing Multi organ Dysfunction syndrome (MODS), septic shock & death if not identified early & treated accordingly. The aim is to study risk factors associated with NF and predictors of outcome.

Settings & design: Prospective observational study in a single tertiary care center.

Materials and Methods:Prospective analysis of patients with NF from March 2018 – August 2019 was done. The known risk factors were studied.

Results: A Total 120 patients were reviewed. Out of which 81 (67.5%) were males and 39 (32.5%) were females. The mortality rate in our study was 14.16%. It was significantly high in patients with CRF (p 0.045), HIV (p <0.001), Diabetes with other risk factors (p 0.003),BSA > 10% (p <0.01), Type 3 culture (0.027),LRINEC score >6 (p 0.015).

Conclusion:NF in patients with known risk factors progresses rapidly, so aggressive treatment should be given at the earliest. Early identification & prompt intervention is the key for better survival outcome in NF.
The Rising trend of obesity among secondary school children of rural background
Authors: Thompson Sheldon , N. Pragati Kumar , Syed Asma , Naaz Faraha 
Published: September 2022

Abstract

Background: Earlier obesity was a disease of the affluent but with changing trend, modernization, sedentary lifestyles overweight/ obesity is increasing in the rural population too. Children of the present generation are prone to obesity which will hamper life in the future. Scientific evidence shows that unhealthy diet and physical inactivity are major global determinants of non-communicable diseases. Aim & Objectives: To estimate the prevalence of obesity, to study the life style factors and to analyze the socio-demographic factors that influence obesity. Materials & Methods:A cross-sectional study was carried out in 400 children between the age group of 12–15 years. Informed consent was obtained from school authorities to collect information from the children. Height and weight were measured using standard procedure and BMI (kg/m) was calculated. Overweight and obesity was assessed by BMI following the WHO guidelines. The questionnaire assessed life style, physical activity, dietary habits and socio-demographic data. Results:Prevalence of obesity was 25.2% (101 children). The statistically significant (p<0.05) factors which influenced obesity was transport to school, physical activity, watching television while eating, consumption of ready made food items, eating in between meals and the socioeconomic status. Conclusion:The prevalence of overweight and obesity was 25.2% as per the BMI (WHO) classification. Use of motor transport, lack of physical activity and sedentary life are major factors.
ANÁLISE SITUACIONAL DA ETIOLOGIA E TERAPÊUTICA DE PACIENTES COM INSUFICIÊNCIA CARDÍACA (IC) NO SISTEMA DE SAÚDE PÚBLICA BRASILEIRO
Authors: Maria Pereira Alves Andreza , Espindola Tamarindo Ana Paula , De Paula Silva Andressa , Mendes Cunha Helena , De Sousa Santos Lara , Oliveira Gonçalves Luanna , Moura Menezes Marcela , Queiroz Souza dos Santos Natália 
Published: September 2022

Objetivo: Avaliar a realidade etiológica e terapêutica dos pacientes com IC em um Centro de atendimento do Sistema Único de Saúde (SUS) no Município de Araguari-MG durante os anos de 2017 a 2021. Métodos: Trata-se de um estudo coorte retrospectivo, explicativo e documental. Sendo uma abordagem de variáveis quantitativas, em que foram incluídos todos os prontuários dos atendimentos da Cardiologia da Policlínica Municipal, no período de 2017 a 2021, totalizando 3.000 consultas de um total de 2.604 pacientes, sendo 970 do sexo feminino e 1.634 do sexo masculino, e utilizou-se um nível de confiança de 95%, erro amostral de 5% com uma distribuição heterogênea totalizando 600 prontuários a serem analisados de forma aleatória. Resultados: Houve prevalência do sexo feminino (60%), a mediana de idades foi de 71 anos. A etiologia mais frequente foi cardiopatia hipertensiva (75,6%), seguida de cardiopatia isquêmica (37,2%) e menos comum a febre reumática (3,50%), sendo que os medicamentos mais prescritos foram Betabloqueadores (BB) (76%), seguidos pelos Bloqueadores de Receptores da Angiotensina (BRA) (48,95%), diuréticos de alça (44,79%) e tiazídicos (44,79%). Conclusão: A terapêutica dos pacientes atendidos no SUS está em concordância com a Diretriz Brasileira de Insuficiência Cardíaca vigente.
South American Summer Monsoon variability over the last millennium in paleoclimate records and isotope-enabled climate models
Authors: Orrison Rebecca , Vuille Mathias , Smerdon Jason E. , Apaéstegui James , Azevedo Vitor , Campos Jose Leandro P. S. , Cruz Francisco W. , Della Libera Marcela Eduarda , Stríkis Nicolás M. 
Published: September 2022

Abstract. The South American Summer Monsoon (SASM) is the main
driver of regional hydroclimate variability across tropical and subtropical
South America. It is best recorded on paleoclimatic timescales by stable
oxygen isotope proxies, which are more spatially representative of regional
hydroclimate than proxies for local precipitation alone. Network studies of
proxies that can isolate regional influences lend particular insight into
various environmental characteristics that modulate hydroclimate, such as
atmospheric circulation variability and changes in the regional energy
budget as well as understanding the climate system sensitivity to external
forcings. We extract the coherent modes of variability of the SASM over the
last millennium (LM) using a Monte Carlo empirical orthogonal function
(MCEOF) decomposition of 14 δ18O proxy records and compare them
with modes decomposed from isotope-enabled climate model data. The two
leading modes reflect the isotopic variability associated with (1) thermodynamic changes driving the upper-tropospheric monsoon circulation
(Bolivian High–Nordeste Low waveguide) and (2) the latitudinal
displacement of the South Atlantic Convergence Zone (SACZ). The spatial
characteristics of these modes appear to be robust features of the LM
hydroclimate over South America and are reproduced both in the proxy data
and in isotope-enabled climate models, regardless of the nature of the
model-imposed external forcing. The proxy data document that the SASM was
characterized by considerable temporal variability throughout the LM, with
significant departures from the mean state during both the Medieval Climate
Anomaly (MCA) and the Little Ice Age (LIA). Model analyses during these
periods suggest that the local isotopic composition of precipitation is
primarily a reflection of upstream rainout processes associated with monsoon
convection. Model and proxy data both point to an intensification of the
monsoon during the LIA over the central and western parts of tropical South
America and indicate a displacement of the South Atlantic Convergence Zone
(SACZ) to the southwest. These centennial-scale changes in monsoon intensity
over the LM are underestimated in climate models, complicating the
attribution of changes on these timescales to specific forcings and pointing
toward areas of important model development.
Comprehensive space–time hydrometeorological simulations for estimating very rare floods at multiple sites in a large river basin
Authors: Viviroli Daniel , Sikorska-Senoner Anna E. , Evin Guillaume , Staudinger Maria , Kauzlaric Martina , Chardon Jérémy , Favre Anne-Catherine , Hingray Benoit , Nicolet Gilles , Raynaud Damien , Seibert Jan , Weingartner Rolf , Whealton Calvin 
Published: September 2022

Abstract. Estimates for rare to very rare floods are limited by the relatively short streamflow records available. Often, pragmatic conversion factors are used to quantify such events based on extrapolated observations, or simplifying assumptions are made about extreme precipitation and resulting flood peaks. Continuous simulation (CS) is an alternative approach that better links flood estimation with physical processes and avoids assumptions about antecedent conditions. However, long-term CS has hardly been implemented to estimate rare floods (i.e. return periods considerably larger than 100 years) at multiple sites in a large river basin to date. Here we explore the feasibility and reliability of the CS approach for 19 sites in the Aare River basin in Switzerland (area: 17 700 km2) with exceedingly long simulations in a hydrometeorological model chain. The chain starts with a multi-site stochastic weather generator used to generate 30 realizations of hourly precipitation and temperature scenarios of 10 000 years each. These realizations were then run through a bucket-type hydrological model for 80 sub-catchments and finally routed downstream with a simplified representation of main river channels, major lakes and relevant floodplains in a hydrologic routing system. Comprehensive evaluation over different temporal and spatial scales showed that the main features of the meteorological and hydrological observations are well represented and that meaningful information on low-probability floods can be inferred. Although uncertainties are still considerable, the explicit consideration of important processes of flood generation and routing (snow accumulation, snowmelt, soil moisture storage, bank overflow, lake and floodplain retention) is a substantial advantage. The approach allows for comprehensively exploring possible but unobserved spatial and temporal patterns of hydrometeorological behaviour. This is of particular value in a large river basin where the complex interaction of flows from individual tributaries and lake regulations are typically not well represented in the streamflow observations. The framework is also suitable for estimating more frequent floods, as often required in engineering and hazard mapping.
Formulation and evaluation of colon targeted extended-release prednisolonematrix tablets
Authors: Patil Chandrashekar. C. , Jorapur Prashant , Naikwadi Akram 
Published: September 2022

The prepared tablets met the compendia limits in termsof physiochemical parameters and dissolution studies. The mixture of 30 mg pectin and 30 mg of xanthan gum as matrix and 10% w/v of Eudragit RS100 solution as coating material werebest suitable in colon targeteddrug delivery system to provide optimum prednisolone release and protect it from SGF andSIF. As a result, colon delivery of prednisolone appeared to be apromising alternative to its traditional oral formulation.
MENAKAR POTENSI KEBANGKRUTAN INDUSTRI FARMASI DI INDONESIA SEBELUM DAN PADA SAAT PANDEMI COVID 19
Authors: Wiarta Iqra , Suryani Ade Irma , Firmansyah Deni 
Published: September 2022

Kebangkrutan adalah suatu kondisi di mana perusahaan tidak mampu lagi untuk mengoperasikan perusahaan dengan baik karena kesulitan keuangan yang dialami tersebut sudah sangat parah. Penelitian ini bertujuan untuk mengetahui dan menganalisis potensi kebangkrutan perusahaan pada industri farmasi di Indonesia (studi kasus pada PT. Kalbe Farma Tbk) sebelum pandemi covid 19 dengan menggunakan model kebangkrutan Zmijewski. Data yang digunakan dalam penelitian ini bersumber dari laporan tahunan perusahaan tahun 2016 sampai dengan 2020.
Berdasarkan pada hasil perhitungan, dapat diketahui bahwa nilai perhitungan dari metode Zmijewski menujukan hasil bahwa PT. Kalbe Farma Periode 2016 sampai dengan 2020 menunujkan bahwa perusahaan tidak berpotensi bangkrut atau dapat diartikan bahwa perusahaan berada dalam keadaan sehat.
PENGARUH CURRENT RATIO DAN DEBT TO EQUITY RATIO TERHADAP RETRUN ON EQUITY PADA INDUSTRI PAKAN TERNAK DI BEI PERIODE 2016 SAMPAI DENGAN 2020 (STUDI KASUS PADA PT. CHAROEN POKPHAND INDONESIA TBK)
Authors: Arniwita Arniwita , Irmanelly Irmanelly 
Published: September 2022

Laporan kinerja keuangan perusahaan merupakan suatu informasi yang dapat digunakan dalam melihat seluruh kegiatan yang dilakukan oleh manajemen dalam mencapai tujuan bisnisnya pada suatu periode tertentu. Melalui penilaian terhadap rasio keuangan akan dapat dijadikan tolok ukur dalam menilai kinerja keuangan perusahan tersebut. Tujuan penelitian ini yaitu untuk mengetahui dan menganalisis kinerja current ratio (likuiditas), Debt to equity (solvabilitas) dan pengaruhnya terhadap Retrun on Equity (Profitabilitas) pada PT. Charoen Pokphand Indonesia Tbk periode 2016 sampai dengan 2020. Metode yang digunakan dalam penelitian ini yaitu analisis kuantitatif dengan sumber data didapatkan berasal dari laporan tahunan perusahaan yang dipublikasikan pada laman perusahaan tersebut periode 2016 sampai dengan 2020.
Hasil Penelitian menunjukan bahwa nilai current ratio (CR), Debt to Equity ratio (DER) dan Retrun on Equity (ROE) selama periode 2016 sampai dengan 2020 cenderun stabil setiap tahunnya dan memiliki peningkatanan dari tahun ke tahun. berdasarkan hasil analisis diketahui juga bahwa rasio CR, DER berpengaruh signifikan terhadap ROE dengan tingkat signifikannya yaitu 0,5.
PERSEPSI MAHASISWA TERHADAP PELAYANAN BIRO ADMINISTRASI AKADEMIK, KEMAHASISWAAAN DAN SISTEM INFORMASI (BAAKSI) UNIVERSITAS MUHAMMADIYAH JAMBI
Authors: Kurniasih Endah Tri , Wiarta Iqra , Hierdawaty Trie , Amrizal Amrizal , Dani Rian 
Published: September 2022

Kualitas Pelayanan adalah taraf atau derajat dari tindakan atau kegiatan yang dapat ditawarkan oleh satu pihak kepada pihak lain, pada dasarnya tidak berwujud dan tidak mengakibatkan kepemilikan apa pun. Tujuan dari penelitian ini yaitu untuk mengetahui dan menganalisis persepsi kualitas pelayanan pada biro admisitrasi akademik, kemahasiswaan dan sistem informasi pada universitas muhammadiyah jambi. metode penelitian yang diguanakan yaitu kuantitatif deskriptif dengan alat analisis regresi linier berganda.
Hasil Penelitian menujukan bahwa secara simultan variabel kepuasan konsumen yang meliputi tangible, reliability, responsiveness, assurance dan emphaty berpengaruh secara parsial terhadap kepuasan mahasiswa. Secara parsial hanya variabel assurance yang berpengaruh terhadap kepuasan Mahasiswa.
EPISTEMOLOGI FIKIH FILANTROPI ISLAM DALAM ZAKAT PROFESI: STUDI FATWA MAJELIS ULAMA INDONESIA NOMOR 3 TAHUN 2003 TENTANG ZAKAT PENGHASILAN
Authors: Bokhori Ali Topan 
Published: September 2022

Paper ini bertujuan untuk mengidintifikasi landasan efistemologi hukum Islam dalam kontruksi Fatwa Majelis Ulama Indonesia Nomor 3 Tahun 2003 Tentang Zakat Penghasilan. Metode yang digunakan kualitatif diskriptif analisis berupa library research dengan pendekatan normatif filosofis dan didukung teori pradigma rasionalisme hukum Islam untuk menganalisis data primer dan skunder. Adapun data primer terdiri dari Fatwa MUI No. 3 Tahun 2003 Tentang Zakat Penghasilan, Peraturan Meteri Agama RI No. 52 Tahun 2014 Tentang Syarat dan Tata Cara Penghitungan Zakat Mal dan Zakat Fitrah serta Pendayagunaan Zakat untuk Usaha Produktif, Musyawarah Nasional Tarjih XXV Tanggal 8 Juli 2000 M, Keputusan Sidang Dewan Hisbah 12 Sya’ban 1423 H Tentang Zakat Profesi, dan Hasil Bahtsul Masail Nahdlatul Ulama. Sebaliknya data sekunder terdiri dari kitab, buku dan artikel ilmiah yang ada relevansinya dengan penelitian ini. Hasil penelitian menunjukkan bahwa epistemologi Fatwa MUI Nomor 3 Tahun 2003 Tentang Zakat Penghasilan menggunakan pradigma rasionalisme hukum Islam dengan aliran epistemologi Bayani, yaitu mengqiyaskan zakat profesi dengan zakat emas senilai 85 gram, kadar zakatnya 2,5%. Dalil yang digunakan oleh MUI. Pertama, ayat al-Qur’an surat al-Baqarah 267, 219 dan al-Taubah 103. Kedua, Hadist yang diriwayatkan oleh Ibn Umar, Abu Hurairah dan Hakim bin Hizam. Ketiga, pendapat Yusuf al-Qardhawi.
Kata Kunci: Epistemologi, MUI, Zakat Profesi
An Analysis of Mantra Used by Sandro in Batanak at Tarusa Village
Authors: Solihin Solihin , Sartika Sartika , Juliadi Ismail 
Published: September 2022

Based on this background, the problems studied in this research are: (1) How is the structure of the spell used by Sandro in the Batanak. (2) What is the meaning of the mantra used by Sandro in Batanak. (3) What is the function of the mantra used by Sandro in Batanak. This study used descriptive qualitative method. Data collection techniques were video recording, interview and documentation. The researchers analyzed the data through the following steps: (1) The data obtained from video recording was analyzed by descriptive qualitative method, (2) The researchers transcribed the video recording, (3) The researchers analyzed the transcription of the video recording contained in the Batanak mantra, (4) Then clarified and described the structure, meaning and functions of the Batanak mantra. Based on the results of the analysis, it can be concluded that the structure of meaning contained in the Batanak mantra has six components, namely the title, opening, intention, suggestion, purpose and closing components. The Batanak mantra has two meanings, namely denotative and connotative, although not all of the denotative meanings have connotative meanings. The languages used in the mantra are Arabic and the Sumbawanese. Then the functions contained in the mantra are based on the expectations of a group of people who are members of the ritual, namely praying for rain.
Peran Orang Tua dalam Pendampingan Belajar Siswa Sekolah Dasar pada Era New Normal di Desa Undaan Lor
Authors: Dinar Ri Asa , Ismaya Erik Aditia , Riswari Lovika Ardana 
Published: September 2022

Penelitian ini adalah penelitian kualitaif dengan tujuan untuk mengetahui peran orang tua dalam pendampingan belajar siwa sekolah dasar pada era new normal di desa Undaan Lor RT 06 RW 02. Jenis penelitian ini adalah kualitatif menggunakan pendekatan studi kasus dengan metode deskriptif. Pengumpulan data dalam penelitian ini adalah wawancara, observasi dan dokumentasi pengecekan keabsahan data menggunakan kredibilitas, transferabilitas, dependabilitas, dan konfirmabilitas. Teknik analisis data yang digunakan dalam penelitian ini menggunakan analisis data reduksi data, penyajian data dan veridikasi data. Hasil penelitian ini menunjukkan bahwa: orang tua yang memiliki pendidikan rendah serta disibukkan oleh pekerjaan kurang maksimal dalam pendampingan belajar siswa di era new normal sehingga mengakibatkan banyak siswa kekurangan pendampingan. Siswa pada orang tua yang berpendidikan tinggi dan mendapatkan pendampingan penuh oleh orang tua lebih beruntung karena tercukupi atas peran pendampingan yang diberikan oleh orang tua. Sehingga berpengaru terhadap proses dan hasil belajar siswa.
Analysis of Cryptocurrency, Bitcoin and the Future
Authors: Manjula.B.C  , Shilpa.B.S  , Sundaresh. M  
Published: September 2022

Technology advances at a rapid rate, and the success of a given technology is almost solely dictated by the market upon which it seeks to improve. Cryptocurrencies may revolutionize digital trade markets by creating a free flowing trading system without fee. The rapid development and growth in the field of information and communication technologies has changed our day to day life. Not only day to day it has changed our traditional pattern of banking and financial transactions. This advancement of information communication technology has helps to use of paper work activities into digital operations. The upgraded technologies have also changed the pattern of financial transactions as well as created a new form of money. Cryptocurrencies are not likely to replace traditional fiat currency, they could change the way internet connected global markets interact with each other, clearing away barriers surrounding normative national currencies and exchange rates. Cryptocurrencies may revolutionize digital trade markets by creating a free flowing trading system without fees. Bitcoin is presented which illuminates some of the recent events and movements that could influence whether bitcoin contributes to a shift in economic paradigms.
Pengaruh Budaya Organisasi Terhadap Tata Kelola Perusahaan pada Rumah Sakit di Jabodetabek
Authors: Yosefin  , Rosalina Anna 
Published: September 2022

Penelitian ini dilakukan untuk mengetahui seberapa jauh budaya organisasi pada rumah sakit mempengaruhi penerapan good corporate governance pada rumah sakit secara signifikan. Penelitian ini juga ingin mengetahui seberapa jauh tipe kepemilikan mempengaruhi budaya organisasi secara signifikan. Variabel independen yang digunakan dalam penelitian ini adalah budaya organisasi pada rumah sakit yang dijabarkan dalam inovasi, detail, orientasi hasil, orientasi orang, orientasi tim, keagresifan, dan kemantapan. Variabel dependen dalam penelitian ini adalah corporate governance yang dijabarkan dalam fairness, transparancy, accountability, dan responsibility. Penelitian ini menggunakan data primer dari kuisioner yang diberikan kepada 150 responden pada tiga rumah sakit. Setiap rumah sakit diambil sampel 50 responden. Pada setiap rumah sakit, kuisioner kuisioner tersebut diberikan kepada 3 orang manajemen, 7 orang dokter, 32 orang perawat, dan 8 orang staf administrasi. Ketiga rumah sakit yang diteliti adalah RSPAD Gatot Subroto, RSAL Mintoarjo, dan RS St. Carolus. Teknik pengambilan sampel yang digunakan dalam penelitian ini adalah purposive sampling. Hipotesis yang digunakan dalam penelitian ini ada dua hipotesis. Uji yang digunakan untuk mengetahui hasil dari penelitian ini adalah statistik deskriptif, uji validitas dan reabilitas, uji kesesuaian model, dan uji hipotesis. Data diproses dan dianalisis menggunakan regresi berganda untuk semua variabel. Hasil dari uji – uji yang dilakukan menunjukkan bahwa budaya organisasi pada rumah sakit tidak mempengaruhi penerapan corporate governance pada rumah sakit secara signifikan. Dan, tipe kepemilikan tidak mempengaruhi budaya organisasi secara signifikan.