bluuebunny/crossref_metadata_2025_split huggingface dataset:
Our Experiences in Acute Arterial Embolism Treatment with Endovascular Techniques in Lower Extremity
Authors: ATAY Mehmet , SAYDAM Onur 
Published: March 2022

Objectives: The study aims to retrospectively evaluate the 1-year results of endovascular treatment with rheolytic thrombectomy(TR) or catheter-directed thrombolytic(CDT) infusion therapy in acute femoro-popliteal bypass graft occlusion.
Methods: The patients who had a history of femoro-popliteal by-pass operation and during their follow-up diagnosed with ipsilateral acute limb ischemia between 2016 and 2018 were included. The total of 13 patients were included and they were divided into two groups according to their treatment methods (RT, n=8 vs CDT, n=5).
Results: There was no statistically significant difference between the two groups in terms of demographic data and Rutherford embolism classification. Reolitic thrombectomy and catheter-directed thromolytic infusion primary patency values were 87.5% and 80% for 6 months, 75% and 60% for 12 months, respectively. Secondary patency values were found to be 100% in both groups for 6 months, and 87.5% and 80% for 12 months, respectively. There was no significant difference between the two groups in terms of primer and sekonder patency.
Conclusion:Endovascular therapy can be preferred in the treatment of acute femoro-popliteal by-pass graft occlusion in selected patient groups due to its less invasiveness, early mobilization, and low mortality and morbidity rates compared to surgery,
Lumbar Posterior Transpedicular Screw Fixation and Fusion Applications; What We Do Peroperatively with 117 Spinal Instability Cases
Authors: BULUT Güray , AYTAR Murat Hamit , GÜDÜK Mustafa 
Published: March 2022

Objective: In this study, we aimed to share our surgical principles and surgical outcomes in cases of fixation and fusion with lumbar posterior transpedicular screw-rod systems in our clinic.
Methods: 117 patients who underwent posterolateral fusion surgery with lumbar posterior transpedicular screw-rod system between 2014 and 2017 were evaluated retrospectively. Dynamic lumbar radiographs, computed tomography and magnetic resonance imaging were performed in all cases before the operation. All patients were operated with microsurgical principles and internal fixation and posterolateral fusion were performed with posterior interpedicular screw-rod systems. Stabilization systems were evaluated with lumbar X-ray and/or computed tomography on the first postoperative day. In the 1st and 3rd months, lumbar X-rays were repeated.
Results: All these patients, in whom lumbar spinal instability was detected clinically and radiologically, had low back and/or leg pain and different levels of neurological deficits. Of the cases, 23 were male and 94 were female. The mean age was 53.4 years. According to the Meyerding classification, there were grade I and II spondylolisthesis in 69, and 8 cases respectively, spinal stenosis in 28 cases, burst fracture in 1 case, compression fracture in 3 cases, disc herniation in 11 cases. The mean follow-up period was 28.6 months.
Conclusions: Meticulous case selection, careful preoperative planning and adherence to spinal microsurgery principles will increase the success rate in lumbar posterior internal fixation and posterolateral fusion surgeries.
Evaluation of Dermatology Consultations Requested from the Pediatric Clinic
Authors: YAVUZ Cahit , UĞUR Cüneyt 
Published: March 2022

Objective: The aim of this study is to evaluate the clinical, demographic, and diagnostic characteristics of pediatric patients consulting the dermatology department.
Methods: Patients who were consulted to the dermatology department from pediatric clinic of XX Hospital between January 2021 and August 2021 were scanned retrospectively. The demographic data of the patients, the pediatric department requesting consultation, their complaints at admission, the reasons for asking for consultation, and the diagnoses they received as a result of the consultation were recorded.
Results: A total of 296 patients, 150 (50.7%) females and 146 (49.3%) males, with a median age of 5.5 years (1.5-10.5 ) were evaluated. The outpatient clinic were seen to have made the most requests for consultation. The most frequent complaints on presentation were seen to be redness of the skin in 168 (56.8%) cases and itching in 36 (12.2%). The five most common diagnoses made as a result of the consultation were unspecified dermatitis in 47 (15.9%) cases, scabies in 34 (11.5%), insect bite in 17 (5.7%), atopic dermatitis in 13 (4.4%), and seborrheic dermatitis in 13 (4.4%). When the diagnoses were examined according to the age groups, unspecified dermatitis was usually seen in the 0-2, 6-11, and 12-18 years age groups and insect bite was more common in the 3-5 years age group.
Conclusion: The establishment of effectively functioning consultation mechanisms not only facilitates a correct diagnosis for the patient and appropriate treatment, but also can shorten the length of hospital stay for pediatric patients and can reduce economic costs.
KALIBRASI MODEL SIMULASI VISSIM
Authors: Raharjo Effendhi Prih , Guntur M. , Umiyati Siti , Sari Novita , Hardianto Dani , Angga Dessy , Handayani Sabrina 
Published: March 2022

Dalam menganalisa transportasi suatu jaringan jalan, banyak ditemui keterbatasan dan kesulitan. Banyak waktu, tenaga dan biaya yang digunakan untuk menganalisa dan mengetahui kinerja lalu lintas. Salah satu perangkat lunak yang dapat digunakan adalah aplikasi PTV Vissim 9. Model Vissim itu sendiri pada dasarnya merupakan given atau terdapat pengaturan yang telah di atur oleh penciptanya dengan karakteristik negara asalnya, yakni negara Jerman dan negara maju lainnya dimana negara tersebut mempunyai karakteristik yang berbeda, dilihat dari kebijakan lalu lintas, pengaturan, manajemen dan rekayasa lalu lintas, moda transportasi dan perilaku pengguna jalan yang didalamnya terdapat pejalan kaki dan pengendara kendaraan. Model simulasi Vissim merupakan permodelan dengan analisa microscopis yang didalamnya merumuskan variabel dan alogaritma berkaitan dengan Driving Behaviour atau perilaku pengguna jalan. Hal ini dimaksudkan untuk mengetahui indikasi dari perilaku pengguna jalan terhadap kinerja lalu lintas secara komprehensif namun dalam lingkup mikro.
FTIR Analysis of Oxidized Tungsten and Tungsten Diboride Nanolayers
Authors: GOLDMANE Annija Elizabete , AVOTINA Liga , ROMANOVA Marina , MUHIN Alexei , ZASLAVSKIS Aleksandrs , KIZANE Gunta , DEKHTYAR Yuri 
Published: March 2022

Tungsten (W) and tungsten diboride (WB2) materials can be used to fabricate electron emission layers in field emission microelectronic devices. The characterization and quality assurance of synthesized films is crucial for the good performance of the devices. W and WB2 nanofilms with a thickness of 150 nm and 200 nm were deposited on the Si-SiO2 substrate by the magnetron sputtering technique. The synthesized layers were thermally treated in a thermal analysis device under various gas flow conditions (varying Ar; N2; synthetic air; air with O2, N2, and moisture (further in this text – laboratory air)) and after oxidation, FTIR (Fourier transform infrared spectrometry) spectra were registered. FTIR spectra of the as-deposited layers showed weak peaks related to Si-O and Si-O-Si bonds from the substrate and considered for the analysis of the layers. Several new peaks occur in the spectra of the thermally treated layers. Of the oxidation layers, new peaks related to nanolayers, were observed W-O bonds, it is noticeable that the spectra vary with each other with signal intensity and offsets. In each experimental environment with various gas flow conditions, there were W=O bonds observed, also in every environment except in laboratory air with the flow, B-O bond was detected for about 1300 – 1350 cm-1 range. It was shown that thermal oxidation of W and WB2 layers can be applied for the analysis of W and WB2 layers on SiO2 substrate by forming W and B oxides using treatment in high temperature and detection of their bonds by FTIR.
Cycle-Time Estimation for Forming Curved Plates Using Neural Networks
Authors: Song Jinho , Lee Junhee , Kim Daewoon , Kim Won-Don , Kang Tae-Won , Kim Jeung-Youb , Nam Jong-Ho , Ko Kwanghee 
Published: March 2022

This article introduces an artificial neural network (ANN) model to determine cycle-times for forming curved hull plates when the target shape is known. The proposed model aids shipbuilding companies in predicting the cycle-times required for ship fabrication. The input parameters are geometric information extracted from the target shape (curvedness, Gaussian curvature, width, and height of the hull plate), and the output parameter is the heating duration per unit area. The structure of the proposed model, which predicts cycle-times for line heating after the cold forming case, consists of two hidden layers. The proposed model is convenient to use and flexible because it only requires retraining when the dataset is changed. The performance of the proposed model was analyzed by five-fold cross-validation and compared with that of a mathematical model obtained from the linear regression analysis method and predefined formulas. The results show that the ANN model is reliable and accurate for the cycle-time prediction of curved hull plates in shipbuilding applications.

Introduction
Shipbuilding companies generally estimate the production cost of a ship based on their previous ships for various purposes before the production planning department begins to optimize the fabrication process. They use the estimated value to refine the overall fabrication process or improve it by reducing unnecessary tasks and maximize the overall production efficiency.
Development and validation of a multi-parameter nomogram for predicting prostate cancer: a retrospective analysis from Handan Central Hospital in China
Authors: Nan Libin , Guo Kai , Li Mingmin , Wu Qi , Huo Shaojun 
Published: March 2022

Background
To explore the possible predicting factors related to prostate cancer and develop a validated nomogram for predicting the probability of patients with prostate cancer.

Method
Clinical data of 697 patients who underwent prostate biopsy in Handan Central Hospital from January 2014 to January 2020 were retrospectively collected. Cases were randomized into two groups: 80% (548 cases) as the development group, and 20% (149 cases) as the validation group. Univariate and multivariate logistic regression analyses were performed to determine the independent risk factors for prostate cancer. The nomogram prediction model was generated using the finalized independent risk factors. Decision curve analysis (DCA) and the area under receiver operating characteristics curve (ROC) of both development group and validation group were calculated and compared to validate the accuracy and efficiency of the nomogram prediction model. Clinical utility curve (CUC) helped to decide the desired cut-off value for the prediction model. The established nomogram with Prostate Cancer Prevention Trial Derived Cancer Risk Calculator (PCPT-CRC) and other domestic prediction models using the entire study population were compared.

Results
The independent risk factors determined through univariate and multivariate logistic regression analyses were: age, tPSA, fPSA, PV, DRE, TRUS and BMI. Nomogram prediction model was developed with the cut-off value of 0.31. The AUC of development group and validation group were 0.856 and 0.797 respectively. DCA exhibits consistent observations with the findings. Through validating our prediction model as well as other three domestic prediction models based on the entire study population of 697 cases, our prediction model demonstrated significantly higher predictive value than all the other models.

Conclusion
The nomogram for predicting prostate cancer can facilitate more accurate evaluation of the probability of having prostate cancer, and provide better ground for prostate biopsy.
Highly pathogenic avian influenza virus of the A/H5N8 subtype, clade 2.3.4.4b, caused outbreaks in Kazakhstan in 2020
Authors: Amirgazin Asylulan , Shevtsov Alexandr , Karibayev Talgat , Berdikulov Maxat , Kozhakhmetova Tamila , Syzdykova Laura , Ramankulov Yerlan , Shustov Alexandr V. 
Published: March 2022

Background
Large poultry die-offs happened in Kazakhstan during autumn of 2020. The birds’ disease appeared to be avian influenza. Northern Kazakhstan was hit first and then the disease propagated across the country affecting eleven provinces. This study reports the results of full-genome sequencing of viruses collected during the outbreaks and investigation of their relationship to avian influenza virus isolates in the contemporary circulation in Eurasia.

Methods
Samples were collected from diseased birds during the 2020 outbreaks in Kazakhstan. Initial virus detection and subtyping was done using RT-PCR. Ten samples collected during expeditions to Northern and Southern Kazakhstan were used for full-genome sequencing of avian influenza viruses. Phylogenetic analysis was used to compare viruses from Kazakhstan to viral isolates from other world regions.

Results
Phylogenetic trees for hemagglutinin and neuraminidase show that viruses from Kazakhstan belong to the A/H5N8 subtype and to the hemagglutinin H5 clade 2.3.4.4b. Deduced hemagglutinin amino acid sequences in all Kazakhstan’s viruses in this study contain the polybasic cleavage site (KRRKR-G) indicative of the highly pathogenic phenotype. Building phylogenetic trees with the Bayesian phylogenetics results in higher statistical support for clusters than using distance methods. The Kazakhstan’s viruses cluster with isolates from Southern Russia, the Russian Caucasus, the Ural region, and southwestern Siberia. Other closely related prototypes are from Eastern Europe. The Central Asia Migratory Flyway passes over Kazakhstan and birds have intermediate stops in Northern Kazakhstan. It is postulated that the A/H5N8 subtype was introduced with migrating birds.

Conclusion
The findings confirm the introduction of the highly pathogenic avian influenza viruses of the A/Goose/Guangdong/96 (Gs/GD) H5 lineage in Kazakhstan. This virus poses a tangible threat to public health. Considering the results of this study, it looks justifiable to undertake measures in preparation, such as install sentinel surveillance for human cases of avian influenza in the largest pulmonary units, develop a human A/H5N8 vaccine and human diagnostics capable of HPAI discrimination.
Gamma Irradiation Induced Chromosome Aberrations in Meiotic Cells of Bread Wheat (Triticum aestivum L.)
Authors: Alam Qamre , Ahmad Khah Mushtaq , Azad Z. R. Azaz Ahmad 
Published: March 2022

Background and Objectives: Due to the ever-increasing human population and rapid urbanization, the available agricultural land becomes limited for the production of food grains. As a result, there is an urgent need for creating genetic variability upon which improved varieties could be made. The technology of induced mutagenesis plays an essential role in inducing genetic variations among crop species where hybridization is very challenging. Therefore, the present study has been designed to assess the mutagenic impact of gamma irradiation on the cytological behaviour of T. aestivum L in M1 and M2 generation.
Materials and Methods: Bread wheat seeds of selected cultivar were irradiated at BARC, Mumbai with five doses. The irradiated and non-irradiated seeds were sown under field condition with three replicates for each dose according to randomized block design to raise the M1 and M2 generations for morphological and meiotic analysis. For meiosis, immature panicles were collected in early morning and immediately fixed in carnoy’s solution for at least 24 hours. Thereafter, anthers from buds were excised and squashed in acetocarmine followed by photomicrography of suitable PMCs to estimate chromosome aberrations.
Results: The results displayed a progressive elevation in the chromosomal aberrations along with a significant influence on seedling emergence, plant survival and pollen fertility. The most frequent meiotic aberrations detected include chromatin clumping, univalents and early chromosome segregations at metaphase and lagging chromosomes, chromatin bridges and chromosome clumping at anaphase/telophase while unorientation, scattering, polarity disturbances and micronuclei were also noticed. In addition, the frequency of these chromosome aberrations significantly decreased in M2 generation depicting the reclamation in genomic structure.
Conclusion: The present investigation supports the discovery that gamma irradiations are very effective in creating rapid genetic variability in crop plants including Triticum aestivum which could be essentially exploited for future mutation breeding programmes. The results revealed that the higher treatment doses are toxic whereas lower doses of gamma irradiations seem quite beneficial in generating promising traits with less toxicity. In this study, the cytotoxicity has increased along with gamma irradiation doses and therefore, the genetic structure of the selected bread wheat cultivar is highly affected, which will possibly create new favorable genetic changes in the following generations that would be useful for plant breeders for its improvement.
Factors Associated with Treatment Failure for Microscopy-positive Pulmonary Tuberculosis at the General Reference Hospital of Beni (DR Congo) between 2010 and 2020: Case-control Study
Authors: Baudouin Kambale Musondivwa , Pascal Kule Posho , Franck Dimoke Okito , Raymond Assani Ramazani 
Published: March 2022

Introduction: Failure to treat microscopy-positive pulmonary tuberculosis (MPT+) poses a risk to public health through the spread of infection and could be a gateway to anti-tuberculosis drug resistance. The aim of this study was to describe the epidemiological characteristics of PMT+ TB patients with treatment failure, to measure the degree of association between the various factors and TB treatment failure, and to formulate recommendations for improving NTP activities.
Methods: This is a retrospective case-control study conducted from 1 January 2010 to 31 December 2020 at the CDTMR of the General Referral Hospital of Beni. The cases are patients treated for PMT+ and who had a therapeutic failure. Three controls for each case were selected among patients with PMT+ who were declared cured. Data analysis was performed using Epi-Info version 3.5.3 for Windows.
Results: 128 patients were included in the study. 32 patients were treatment failures. The mean age of cases and controls was 42 years (+/- 14), the M/F sex ratio was 31 and 2.4 in cases and controls respectively, urban residents accounted for 90.3% and 83.2% in cases and controls respectively. Bivariate analysis showed a significant association between treatment failure and weight loss at first control (OR=1.55), non-decrease in bacillary density at first control (OR=25.5) and treatment discontinuation (OR=20.5). After adjustment, weight loss of 1 kg (adjusted OR=1.92), no decrease in BAAR density (adjusted OR=8.30) and treatment discontinuation (adjusted OR=12.2) remained significantly associated with treatment failure.
Conclusion: Active surveillance should be instituted in TB patients with PMT+ who present at first check-up with weight loss, non-decrease in bacillary density on direct examination and/or a notion of treatment discontinuation.
Long Scarf Related Injuries in Female Bike Riders Reported at Different Tertiary Care Hospitals Karachi
Authors: Iqbal Sadaf , Memon Farhana , Zulfiqar Bushra , Shafaatullah . , Memon Ashfaq Ahmed , Noor Maryam 
Published: March 2022

Objective: To determine the frequency of long scarf related injuries in female bike riders.
Study Design: This is an observational study.
Setting: This study was conducted in the emergency department of a tertiary care hospital in Karachi and aims to calculate the type of injury due to long scarf in female bike riders. It was conducted during the period of Dec, 2020 to Nov, 2021.
Materials & Methods: Participants visiting the emergency department due to motor bike accidents and female patients were screened for long scarf related injuries. Statistical analysis was done by SPSS version 21 and descriptive statistics were used.
Results: For one year time, we received 174 patients due to motor bike accidents and 20.6% injuries were due to long scarf in females. As 36 patients matched our inclusion criteria due to long scarf while riding a motor bike. The mean age of females was found to be 34 years (range 16-55 years). Majority of the patients had more than one site of injury and left leg fracture was the most common injury found in 44.6% of females. Out of 32 patients, 14 patients required admission urgently.
Conclusion: A considerable number of injuries and deaths can be prevented by simple interventions and carefulness while riding on motorcycle. We have identified this problem only in a small group of population but this issue needs to be highlighted at a higher place.
Anti-cariogenic & Cytotoxic Activity of Red Sandal (Pterocarpus santalinus) Ethanolic Extract
Authors: Palani Harini , Arivarasu Lakshminarayanan , Rajeshkumar S. , Thangavelu Lakshmi 
Published: March 2022

Introduction: Pterocarpus santalinus, with the common names red sanders, red saunders, red sandalwood, Rakt Chandan, and saunderswood, is a species of Pterocarpus endemic to the southern Eastern Ghats mountain range of South India. This tree is valued for the rich red colour of its wood.The use of ethanolic extract is a cost-effective way to produce a quality extract from a large volume of plants.Pterocarpus santalinus has a characteristic anti-cariogenic and cytotoxic activity.This study aimed to find the Anti cariogenic and cytotoxic activity of Pterocarpus santalinus (Red sandal) ethanolic extract preparation.
Materials and Methods: The anticariogenic activity was done by using agar well diffusion technique and the cytotoxic activity was done by Brine Shrimp Lethality Assay. Pterocarpus santalinus were purchased commercially from an herbal health centre, in Chennai. The obtained powder Pterocarpus santalinus stored in an airtight container. 5 gram of powder is mixed with 50 ml of ethanol and kept in the orbital shaker for 72 hours , after it has boiled in a heating mantle at 62- 70 degree c for 5-10 min. The extract is filtered using whatman filter paper 1.The filter extract again contracted using heating mantle.
Results: The extract shows very good anticariogenic and cytotoxic activity of P.santalinus ethanolic extract by using Brine Shrimp Lethality Assay.
Conclusion: The Anti-cariogenic and cytotoxic activity of Pterocarpus santalinus ethanolic extract preparation was effective.