bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of Covid‐19 on gamete shipping by Australian and New Zealand patients
Authors: Everingham Sam , Whittaker Andrea 
Published: October 2022

BackgroundCross‐border surrogacy and egg donor arrangements are an increasingly common means to family building. Establishing patterns of use has always been difficult in relation to Australian patients. Accurate data is stymied by lack of documentation of international third‐party reproductive care available to Australian authorities. When international travel bans came into effect, it is hypothesised that those planning to use cross‐border reproductive care had to rely significantly more on local in vitro fertilisation (IVF) clinics for services such as sperm freezing, embryo creation and gamete release procedures.AimTo quantify and characterise the impact of the Covid‐19‐related travel ban on international and interstate gamete shipping by Australian IVF clinics.Materials and methodsThirty‐one Australian and New Zealand IVF clinics were invited to provide de‐identified data on interstate and international gamete export applications from two 12 month time periods pre‐ and during Covid‐19‐related international travel lockdowns. Seven IVF organisations provided data on: patient age; type of gametes exported; destination country/state; and date gamete release approved.ResultsMost gametes (78%) were shipped to another Australian IVF clinic and 22% internationally. Patient‐initiated shipping domestically and internationally both showed significant increases when comparing pre‐ and post‐Covid datasets. Of the 21 destination countries reported for international shipments, the US was the commonest (39%), followed by Ukraine (21%) and Canada (9%).ConclusionsThe inability of involuntarily infertile patients to travel internationally, rather than halt cross‐border reproductive care, has led to a significant increase in the uptake of gamete shipping. The high proportion of internationally shipped gametes going to the US and Ukraine is likely a reflection of the availability of surrogates and donors and more amenable legal frameworks.
Pattern-Based Clustering of Daily Weigh-In Trajectories Using Dynamic Time Warping
Authors: Bothwell Samantha , Kaizer Alex , Peterson Ryan , Ostendorf Danielle , Catenacci Victoria , Wrobel Julia 
Published: October 2022

Abstract
“Smart”-scales are a new tool for frequent monitoring of weight change as well as weigh-in behavior. These scales give researchers the opportunity to discover patterns in the frequency that individuals weigh themselves over time, and how these patterns are associated with overall weight loss. Our motivating data come from an 18-month behavioral weight loss study of 55 adults classified as overweight or obese who were instructed to weigh themselves daily. Adherence to daily weigh-in routines produces a binary times series for each subject, indicating whether a participant weighed in on a given day. To characterize weigh-in by time-invariant patterns rather than overall adherence, we propose using hierarchical clustering with dynamic time warping (DTW). We perform an extensive simulation study to evaluate the performance of DTW compared to Euclidean and Jaccard distances to recover underlying patterns in adherence time series. In addition, we compare cluster performance using cluster validation indices (CVIs) under the single, average, complete, and Ward linkages and evaluate how internal and external CVIs compare for clustering binary time series. We apply conclusions from the simulation to cluster our real data and summarize observed weigh-in patterns. Our analysis finds that the adherence trajectory pattern is significantly associated with weight loss.
Topping of naturally dyed wool fabrics with different natural dye sources
Authors: Benli Hüseyin , Aydınlıoğlu Ömer , Yılmaz Fazlıhan , Bahtiyari Muhammed İbrahim 
Published: October 2022

AbstractWool fabrics can be dyed with synthetic dyes and even with natural dyes. To present a different aspect to the coloration of wool, the current study was focused on a topping process (ie, the dyeing of wool that was already dyed) with different natural dye sources. For this purpose, the fabrics that were already dyed with a natural dye source were once again dyed with two different natural dyes. In bottom dyeing (bottoming), fabrics were dyed with hops (Humulus lupulus L.) in the presence of different mordanting agents. Then the dyed, washed and dried samples were once again dyed (topping) with two different natural dye sources. For topping, powdered madder and acorn were tested in direct dyeing of wool samples. Finally, the colour changes were analysed with the use of a spectrophotometer. The study demonstrates that such a process (ie, bottoming with hops in the presence of different mordanting agents and then topping with madder or acorn) can be a way of obtaining different shades and colours with sufficient/good fastness values by natural dyeing.
A strategic approach of the crucial elements for the implementation of digital tools and processes in higher education
Authors: Esteve‐Mon Francesc M. , Postigo‐Fuentes Ana Yara , Castañeda Linda 
Published: October 2022

AbstractImplementation of digital tools and processes in Higher Education Institutions (HEIs) as an emergent activity depends on the sociomaterial relationships between institutional factors that dynamically interact with each other. This article systematically explores through a literature review some of the most relevant and up‐to‐date published studies to identify the ‘important factors’ to consider for the implementation of digital tools and processes in HEI. The goal of the paper is to turn these factors, conceived initially as previous conditions or characteristics of the institutions or people, into a list of strategic elements to be fostered by HEI leadership teams to promote better implementation of digital tools and processes in their institutions. In the final part of this work, we propose a framework that reflects these elements in a visual approach that highlights the activity‐centred character of the framework as well as the emergent character of the implementation process itself.
Acute effects of aerobic versus resistance exercises on cognitive function in individuals with intellectual disability
Authors: Borji Rihab , Affes Sana , Zarrouk Nidhal , Sahli Sonia , Rebai Haithem 
Published: October 2022

AbstractBackgroundThis study compared the acute effects of aerobic (AE) and resistance (RE) exercise on reaction time (RT) and working memory (WM) in individuals with intellectual disability.MethodsRT tests and Corsi test for WM were performed before and after three intervention sessions: AE, RE, or control session consisting on watching video.ResultsThe RT values decreased significantly (p < .001) after both of AE and RE with higher extend after the RE but did not vary following the control session. Corsi scores increased significantly (p < .001) after AE but not after RE or control session.ConclusionsThese findings suggest that the effects of acute exercise on cognitive function in individuals with intellectual disability depend on the exercise mode as well as the nature of the cognitive task. The RE seems to be more recommended for RT enhancement whereas only the aerobic one could improve WM in these individuals.
A novel wide‐band dielectric imaging system to guide radiofrequency ablation for pulmonary vein isolation
Authors: Maurer Tilman , Flindt Max , Jularic Mario , Lemes Christine , Akbulak‐Stegli Ruken Özge , Gunawardene Melanie A. , Hartmann Jens , Eickholt Christian , Willems Stephan , Schäffer Benjamin 
Published: October 2022

AbstractIntroductionRecently, the wide‐band dielectric mapping system Kodex‐EPD was introduced. This study reports the first clinical experience using a novel system to guide pulmonary vein isolation (PVI) with radiofrequency (RF) ablation.Methods and ResultsThe study included 20 consecutive patients undergoing de‐novo PVI for symptomatic paroxysmal or persistent atrial fibrillation guided by Kodex‐EPD. The primary efficacy endpoint was successful PVI. Secondary endpoints included procedural parameters and complications. In all 20 patients (mean age 68 ± 8 years, 12 male patients, paroxysmal fibrillation in 14/20 [70%] patients), PVI was successfully completed. One patient underwent additional cavo‐tricuspid isthmus ablation for concomitant typical atrial flutter and one patient required additional ablation of a focal atrial tachycardia. A conventional three‐dimensional image of the left atrium as well as the innovative endocardial panoramic view were used to guide catheter manipulation and ablation. Median procedure time was 115 [1st; 3rd quartile 93,75; 140] min and median total fluoroscopy time was 9.9 [9.7; 11.2] min, of which a median of 0.8 [0.6; 0.9] min was required to create left atrial maps. Complete left atrial imaging using Kodex‐EPD was achieved within a median of 7.1 [5.7; 8.3] min. Median RF ablation time was 45.1 [34.6; 58.7] min. No major complications were observed.ConclusionRF ablation PVI guided by Kodex‐EPD seems safe and feasible. The system provides effective three‐dimensional guidance for PVI.
Web‐based training intervention to increase physical activity level and improve health for adults with intellectual disability
Authors: Fjellstrom S. , Hansen E. , Hölttä J. , Zingmark M. , Nordström A. , Lund Ohlsson M. 
Published: October 2022

AbstractBackgroundIndividuals with intellectual disability (ID) are less physically active, have a higher body mass index (BMI) and are at greater risk for cardiovascular diseases (CVDs) than people without ID. The purpose of the study was to explore the effectiveness of a web‐based training programme, consisting of 150 min of activity per week, on the health of people with ID.MethodParticipants with ID living in supported accommodation (n = 28, 48% female, age = 36.4 ± 9.56 years) participated in a web‐based training programme, consisting of a combination of exercises (endurance, strength balance and flexibility) of moderate intensity, 50 min, three times per week for 12 weeks. The body composition and waist circumference (WC) were measured, and questionnaires were used to assess enjoyment, quality of life (QoL) and physical activity (PA) level. Descriptive statistics and pairwise comparison pre and post intervention were carried out.ResultsA total of 22 out of 28 participants completed the 12‐week training intervention with 83% mean attendance of training sessions. The intensity of the PA level increased and a decrease in fat mass of 1.9 ± 2.4 kg, P < 0.001 and WC of 3 ± 5 cm, P = 0.009 were observed. Enjoyment of training sessions was 3.9 out of 5, and no differences in QoL were found.ConclusionA web‐based training programme is an effective tool for improving health parameters of people with ID and offers a new way for caregivers to enhance the PA for the target group.
Laser‐based sample preparation for high‐resolution X‐ray‐computed tomography of glasses and glass ceramics
Authors: Krause Michael , Thieme Christian , Schusser Georg , Höche Thomas 
Published: October 2022

AbstractX‐ray‐computed tomography with sub‐micron resolution (nano‐CT) is one of the most useful techniques to examine the 3D microstructure of materials down to voxel sizes 10 nm. However, since size and shape of samples have considerable influence on acquisition time and data quality, adapted and universally applicable workflows are needed. Three novel workflows for sample preparation using ultra‐short pulsed lasers are presented which allow for reproducible fabrication, safe extraction and mounting of samples. Their application potential is illustrated via nano‐CT measurements of glass ceramics as well as a laser‐modified glass. Since the according sample geometries take also the requirements of other analytical techniques such as transmission electron microscopy into account, samples prepared according to the new workflows can be furthermore seen as a starting point for correlative microstructural analyses involving multiple techniques.
Telehealth during the pandemic: Patient perceptions and policy implications
Authors: Crouch Jacob , Winters Karen , Zhang Lei , Stewart Mary W. 
Published: October 2022

AbstractIntroductionTelehealth's potential to improve access to specialty health care, increase favorable patient outcomes, and save money demands attention. Unfortunately, patients often fail to embrace telehealth. The COVID‐19 pandemic fueled greater telehealth usage globally. Little is known about patient perceptions of telehealth in the context of a pandemic. Therefore, we sought to understand patient perceptions of telehealth during the COVID‐19 pandemic and explore relevant policy implications.DesignResearchers used a cross‐sectional, non‐experimental design to survey 366 patients across two telehealth programs at a Mississippi academic health sciences center between November 1, 2021 and November 15, 2021.MethodsAs part of a larger, psychometric study on patient acceptance of telehealth, participants rated the item, “The COVID‐19 pandemic has made me more open to using telehealth” on a 5‐point Likert scale (1 = strongly disagree; 5 = strongly agree). Means of the different groups were analyzed using independent t‐test and one‐way ANOVA with Bonferroni post‐hoc multiple comparisons.ResultsOf the total participants, 73% (n = 366) either agreed or strongly agreed that the COVID‐19 pandemic had made them more open to using telehealth. Significant differences existed by age (p = 0.016), race/ethnicity (p = 0.015), and sex (p < 0.001), however, groups did not differ by age during post‐hoc analysis. A significant difference in the mean responses was observed between black participants (M = 4.29) and white participants (M = 3.91; p = 0.011). In addition, female participants (M = 4.11) rated the item higher than male participants (M = 3.65).ConclusionAs access to telehealth increased due to the COVID‐19 pandemic, patients' perceptions to telehealth seem to have shifted in the positive direction as well. Findings may be used to support expansion of telehealth and advocacy for patients in a variety of settings.Clinical RelevanceStudy findings indicate that participants of telehealth are more open to using telehealth due to the COVID‐19 pandemic. Implementing telehealth should be a priority to increase access to care for those who have limited access to specialty care, and policymakers should advocate to decrease barriers to telehealth within their institutions.
Efficacy of the continuous use of a lotion with carbon dioxide on male subjects with mild acne
Authors: Kiyozuka Aiko , Kajiyama Asami , Ootsuki Rie , Hosokawa Masaru , Miyaki Masahiro , Takagi Yutaka 
Published: October 2022

AbstractObjectiveAcne vulgaris is caused by dyslipidemia, dyskeratosis and/or abnormal bacterial growth. The obstruction of skin pores due to hyperkeratosis of the infundibulum contributes to the formation of comedones. Thus, normalizing keratinization of epidermal cells in skin pores might be useful to improve acne. Recently, it has been found that the transcutaneous application of carbon dioxide (CO2) regulates imbalances of the desquamatory process. In this study, we evaluated the efficacy of a skin lotion containing CO2 on mild acne.MethodsTwenty‐four healthy Japanese males (20–29 years old) with mild acne attended this evaluation. The subjects were divided into 2 groups, one group used a skin lotion containing CO2 and the other group used a skin lotion without CO2. Following facial washing, each subject topically applied the skin lotion with or without CO2 twice a day for 4 weeks. Prior to the start of the evaluation (week 0) and following 2 and 4 weeks of treatment, acne symptoms were assessed by a dermatologist and by instrumental measurements.ResultsTopical application of the skin lotion with CO2 for 4 weeks significantly improved acne symptoms, which was recognized by the subjects. However, treatment with the skin lotion without CO2 did not improve acne symptoms. This improvement of acne symptoms by CO2 was not accompanied by changes in sebum levels, skin surface pH, skin capacitance, or porphyrin levels.ConclusionThe transcutaneous application of a lotion with CO2 improves acne symptoms by normalizing keratinization without affecting skin surface conditions.
Autoimmune‐mediated encephalitis and mimics: A neuroimaging review
Authors: Liang Conan , Chu Eleanor , Kuoy Edward , Soun Jennifer E. 
Published: October 2022

AbstractAutoimmune encephalitis is a category of autoantibody‐mediated neurological disorders that often presents a diagnostic challenge due to its variable clinical and imaging findings. The purpose of this image‐based review is to provide an overview of the major subtypes of autoimmune encephalitis and their associated autoantibodies, discuss their characteristic clinical and imaging features, and highlight several disease processes that may mimic imaging findings of autoimmune encephalitis. A literature search on autoimmune encephalitis was performed and publications from neuroradiology, neurology, and nuclear medicine literature were included. Cases from our institutional database that best exemplify major imaging features were presented.
Intergenerational contact during and beyond COVID‐19
Authors: Drury Lisbeth , Abrams Dominic , Swift Hannah J. 
Published: October 2022

AbstractIntergenerational contact is crucial for promoting intergenerational harmony and reducing ageism. However, the COVID‐19 pandemic has disrupted and changed the nature and frequency of intergenerational contact. In addition, research suggests that both ageism towards older adults and intergenerational threat regarding succession and consumption, have increased. Through the lens of the Temporally Integrated Model of Intergroup Contact and Threat (TIMICAT; Abrams & Eller, 2016), we explore the implications of these changing dynamics on ageism towards older adults during and beyond the COVID‐19 pandemic. Our review reveals that research into intergenerational contact needs to articulate both the time course and salience of contact and threats before making predictions about their impacts on prejudice. The implications of understanding how contact and threat combine to affect ageism for policy and practice are discussed in relation to employment, education, and intergenerational contact programs. We highlight that policy makers play a key role in promoting intergenerational harmony through the reduction of narratives that inflame intergenerational tensions and threat.
Probiotic supplementation in healthy pre‐school‐aged children: What, why, how and when?
Authors: Irwin Nicola , Currie Marian J , Davis Deborah 
Published: October 2022

AimWe previously published the prevalence and predictors of probiotic use among a cohort of healthy 4 and 5‐year‐old children. Here we explore the species and strains most commonly used, the reasons probiotics are used, perceptions of the impact on children's health and parental behaviours around probiotic supplementation in children.MethodsParents of 4 and 5‐year‐old children living in the Australian Capital Territory were invited to participate in an observational, cross‐sectional study by completing a web‐based survey between February and May 2020. Data concerning 481 children were eligible for analysis. Results are presented as simple proportions, with odds ratios and 95% confidence intervals where appropriate.ResultsLacticaseibacillus rhamnosus and Bifidobacterium animalis subsp. lactis were the most frequently reported species, and Lacticaseibacillus rhamnosus GG was the most frequently reported strain. The most common reason for administering probiotics to the 228 (47.4%) of 481 children ever exposed was to promote general health (54%). Half (51%) of parents perceived probiotics had improved their child's general health, although this was more likely for children who had recently (odds ratio (OR): 2.69, 95% confidence intervals (CI): 1.47–4.93) or regularly (OR: 2.92, CI: 1.46–5.85) used probiotics or whose parent had recently used probiotics (OR: 2.47, CI: 1.34–4.55). Initial exposure to probiotics occurred before the age of 2 years in 65% of the cohort.ConclusionThis community‐based study suggests that parents use probiotics primarily to improve children's general health and with modest perceived effect. The long‐term effects of early and prolonged exposure to probiotics are not well understood.
Actigraphy in studies on insomnia: Worth the effort?
Authors: Rösler Lara , van der Lande Glenn , Leerssen Jeanne , Cox Roy , Ramautar Jennifer R. , van Someren Eus J. W. 
Published: October 2022

SummaryIn the past decades, actigraphy has emerged as a promising, cost‐effective, and easy‐to‐use tool for ambulatory sleep recording. Polysomnography (PSG) validation studies showed that actigraphic sleep estimates fare relatively well in healthy sleepers. Additionally, round‐the‐clock actigraphy recording has been used to study circadian rhythms in various populations. To this date, however, there is little evidence that the diagnosis, monitoring, or treatment of insomnia can significantly benefit from actigraphy recordings. Using a case–control design, we therefore critically examined whether mean or within‐subject variability of actigraphy sleep estimates or circadian patterns add to the understanding of sleep complaints in insomnia. We acquired actigraphy recordings and sleep diaries of 37 controls and 167 patients with varying degrees of insomnia severity for up to 9 consecutive days in their home environment. Additionally, the participants spent one night in the laboratory, where actigraphy was recorded alongside PSG to check whether sleep, in principle, is well estimated. Despite moderate to strong agreement between actigraphy and PSG sleep scoring in the laboratory, ambulatory actigraphic estimates of average sleep and circadian rhythm variables failed to successfully differentiate patients with insomnia from controls in the home environment. Only total sleep time differed between the groups. Additionally, within‐subject variability of sleep efficiency and wake after sleep onset was higher in patients. Insomnia research may therefore benefit from shifting attention from average sleep variables to day‐to‐day variability or from the development of non‐motor home‐assessed indicators of sleep quality.