bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deep brain stimulation for refractory obsessive-compulsive disorder: A review and analysis of the FDA MAUDE database
Authors: Porwal Mokshal H. , Karra Hamsitha , Sharma Umesh , Bhatti Danish 
Published: September 2022

Background:
Deep brain stimulation (DBS) is used as a treatment option for patients diagnosed with a form of obsessive-compulsive disorder (OCD) that is highly resistant to conventional treatment methods. In 2009, DBS was granted a humanitarian device exemption-approval by the Food and Drug Administration after promising preliminary data. Monitoring of long-term safety data through post market surveillance of adverse events has not yet been conducted for DBS in OCD patients. This study aims to address this critical knowledge gap.

Methods:
All patient- and device-related (PR; DR) reports from January 1, 2012, to December 31, 2021, were downloaded and compiled from the manufacturer and user facility device experience (MAUDE) database pertaining to DBS for OCD using the product class name “Deep Brain Stimulator For OCD.” Data in this study were examined using descriptive statistics to evaluate for frequency of reporting.

Results:
The most frequently reported PR adverse event categories included psychiatric (40%), neurological (19%), other (14%), decreased therapeutic response (10%), and infections (10%). The most frequent DR reports were high impedance (14%), energy output problem (7%), battery problem (7%), malposition of device (7%), and improper/incorrect procedure or method (7%).

Conclusion:
The PR and DR adverse events in our study align with the previous findings of adverse events. They also further solidify that DBS for refractory OCD may be a viable option for the right patient population. However, further studies are essential given the limitations of the MAUDE database.
Gerardo Martínez Delgado, "La experiencia urbana. Aguascalientes y su abasto en el siglo XX"
Authors: Méndez Rojas Diana Alejandra , Franco de los Reyes Diego Antonio 
Published: September 2022

El libro de Gerardo Martínez Delgado La experiencia urbana. Aguascalientes y su abasto en el siglo xx es una valiosa contribución a la historiografía urbana y regional, así como para los estudios del cambio tecnológico dirigidos a explicar sus ritmos y vaivenes. En similitud a lo hecho por Jaime Humberto Hermosillo con las emociones en La pasión según Berenice,[1] Martínez Delgado nos convence de que Aguascalientes —ciudad intermedia del occidente mexicano— es un territorio de límites porosos que convoca a repensar la relación campo-ciudad, las escalas de análisis y lo universal de los asentamientos urbanos. Desde este posicionamiento, los argumentos del autor no ceden ante al examen de lo particular, de la urbanización o lo moderno, y en su lugar apuestan por el estudio de la experiencia urbana, entendida como un conjunto de transformaciones en los usos, actividades y ocupaciones del espacio, aparejados con las ideas que las sustentan. Se consideran así, los cambios en los hábitos de la población y el funcionamiento de la urbe atendiendo sus relaciones con el exterior, en un periodo que va de 1884 a 1972; práctica inusual en la academia mexicana y en las pautas de la creación académica imperantes, que dejan poco margen a las investigaciones de largo aliento.

[1] Jaime Huberto Hermosillo (Director), La pasión según Berenice, 1976.
Birth injuries, types and risk factors: A Study at Children Hospital Complex Multan.
Authors: Abdur Rehman  , Nazia Fatima  , Aashee Nadeem  
Published: September 2022

Objective: To identify the types and risk factors associated with birth injuries. Study Design: Observational study. Setting: Department of Neonatology, The Children’s Hospital and the Institute of Child Health, Multan Pakistan. Period: November 2019 to July 2020. Material & Methods: A total of 52 neonates admitted in neonatology unit with birth injuries were included. Clinical examination was done to note possible birth injuries. Characteristics of neonates like gender, gestational age, body weight, maternal age and mode of delivery were calculated. Risk factors like difficult labour and instrumentation were described. Pattern and types of birth injuries were highlighted. Results: In a total of 52 neonates with birth injuries, there were 39 (75.0%) male and 13 (25.0%) female representing a male to female of 3:1. Majority of the babies were term born 43 (82.7%). There were 27 (51.9%) babies weighing > 3000 grams. The highest incidence of birth injuries were recorded in normal vaginal deliveries and least in forceps deliveries. Difficult labour was the most common risk factor observed in 30 (57.7%) cases. Extracranial bleeds were seen in 23 (44.2%) neonates while soft tissue injuries were noted in 15 (28.8%) cases, Erb’s paralysis was noted in 5 (9.61%) babies and fractures in 9 (17.3%) babies. Conclusion: Extracranial bleeds were the most common type of birth injuries, followed by soft tissue injuries, fractures and nerve injuries. Difficult labour was the most common risk factor associated with birth injuries.
Rainfall and Temperature Perception among Farmers in India: A Study of Bundelkhand Region
Authors: Jatav Surendra Singh 
Published: September 2022

Climate change has impacted the crop yield and affected the livelihoods of the farmers. Using a systematic random sampling technique, 200 samples were collected from two districts, viz., Jhansi and Jalaun of Bundelkhand region, India from September to November 2017, while rainfall and temperature data were collected from 1969 to 2017 from the Indian Meteorological Department of India to find the link between farmers’ perception on rainfall & temperature, and district’s rainfall and temperature pattern in long-term. Different statistical tools such as the Man Kendall test was employed to examine the rainfall and temperature trends, while the Breusch-Pagan test was used to check heteroscedasticity in the model. Further, the binary logistic regression model was also used to examine the determinants of farmers’ perceptions using socioeconomic variables. The results confirm based on the majority of the farmers’ perception that temperature has increased, while rainfall has declined. These results are in a similar line with the district’s rainfall and temperature trends. The regression results suggest that gender, education, and access to toilets are less likely to influence the farmers’ perception of climate change, while age, income, and access to electricity are significantly likely to influence the farmers’ perception of climate change. Hence, policy should be implemented to enhance rural farming communities’ awareness of climate change by providing training and creating awareness.
Las empresas y el desafío para superar la crisis originada por la COVID-19
Authors: Esteban Espinoza David 
Published: September 2022

Los desafíos de los gobiernos ante el nuevo escenario de la economía global muestran las dificultades a las que se enfrentaron ante las condiciones impuestas por la pandemia. En el plano internacional, los efectos sanitarios y económicos de la expansión del virus en un mundo fragmentado y no coordinado, con países compitiendo entre sí por insumos y recursos, en algunos casos en desigualdad de condiciones, con capacidad de oferta de productos limitada por la alta demanda o las reglas de la economía de mercado, vender al mejor postor o dar preferencia al cliente que más compra.
A Comparison of the Cost and Consumption of Sevoflurane and Litholyme at Total Gas Flow Rates of 1 and 2 Liters Per Minute: a Randomized Controlled Trial
Authors: Kitsiripant Chanatthee , Boonmuang Piachompoo , Chatmongkolchart Sunisa , Tanasansuttiporn Jutarat , Liochaichan Natnicha , Jantawong Nuttipa 
Published: September 2022

Objective: This study aimed to compare the cost-effectiveness of low-flow (1 liter per minute (LPM)) and medium-flow (2 LPM) anesthesia. Material and Methods: Seventy patients aged 18–60 years who were undergoing elective surgery under general anesthesia were randomly allocated to receive a total gas flow rate of 1 LPM (group 1) and 2 LPM (group 2) during the maintenance of anesthesia. The primary outcome was to compare the cost and consumption of sevoflurane and litholyme. The secondary outcomes were hemodynamic stability and time to extubation. Results: The cost and consumption of sevoflurane in group 1 (197.3 Thai Bahts (THB)/hour (hr) and 9.6 milliliter (ml)/ hr) were significantly less than those in group 2 (303.2 THB/hr and 14.8 ml/hr; p-value<0.001). Although there was no difference in the cost and consumption of litholyme between the two groups, the summary cost of sevoflurane and litholyme in group 1 (237.7 THB/hr) was significantly less than that in group 2 (339.6 THB/hr; p-value<0.001). The mean arterial pressure, heart rate, and time to extubation were not significantly different in both groups. Conclusion: Patients undergoing elective surgery under general anesthesia with a total flow of 1 LPM can save on the cost of sevoflurane and litholyme, which is equivalent to 101.9 THB/hr.
Kerjasama Pemerintah Kabupaten Tana Toraja dan Swisscontact dalam Pengembangan Pariwisata Tahun 2014-2019
Authors: Cici Pratiwi  , Susanti Eni , Asma Amin  , Abbas Wandi , Sutrisno  
Published: September 2022

Penelitian ini bertujuan untuk mengetahui upaya kerja sama yang telah dilakukan oleh Pemerintah Kabupaten Tana Toraja melalui Dinas kebudayaan dan Pariwisata Tana Toraja bersama dengan Swisscontact dalam mengembangkan Pariwisatanya. Penelitian ini menggunakan tipe penelitian deskriptif kualitatif, metode pengumpulan data penelitian ini menggunakan wawancara sebagai data primer dan telah pustaka sebagai data sekunder. Adapun hasil dari penelitian ini yaitu upaya yang dilakukan Pemerintah Kabupaten Tana Toraja, secara mandiri melibatkan beberapa kelompok, organisasi lokal pada bidang pariwisata untuk mendukung aktivitas pengembangan ini dengan didampingi oleh Swisscontact. Aktivitas ini didanai langsung oleh Sekretariat Negara untuk Urusan Ekonomi (SECO) Swiss. Adapun Strategi yang telah dilakukan Swisscontact dengan PEMDA antara lain, melakukan promosi, pengadaan kegiatan kreatifitas produksi, sosialisasi, pemasaran, pengadaan kelompok sadar wisata, pengadaan sarana-prasarana disetiap objek wisata dengan peluangan yang didapatkan, Swisscontact mampu menjadi pendorong PEMDA Kabupaten Tana Toraja baik dalam bantuan pendanaan untuk meningkatkan kualitas dan industri pariwisatanya, dan dapat menjadikan pariwisata Tana Toraja sebagai ikon pariwisata Internasional, kemudian tantangan yang dihadapi yaitu: kurangnya Sumber Daya Manusia dalam pengelolaan SDA, serta sarana prasarana yang kurang memadai,dan sebagainya. Sehingga hadirnya Swisscontact dalam kerjasama ini sangat membantu dan memberikan pengaruh yang sangat besar dalam peningkatan industri pariwisata yang berkelanjutan di Kabupaten Tana Toraja.
Linking Land and Sea
Authors: Reardon-Smith Susan 
Published: September 2022

Abstract
Australia's harsh policy response to asylum seekers appears to be an extreme measure for a country that thinks of itself as a liberal democracy. Confining analyses of this regime to refugee law and policy overlooks the ways that Australia's colonial history, Indigenous dispossession, and contemporary race relations interact with one another. This article argues that these historical dynamics are essential to understanding the Australian government's response to asylum seekers in the present day, with asylum-seekers and Indigenous peoples in Australia both being utilized as tools of modern statecraft to shore up the legitimacy of the Australian state. Attention is drawn to parallels between the treatment of both Indigenous peoples and asylum seekers by the Australian government, with the increasingly harsh response to asylum seekers in Australian politics coinciding with the expansion of land rights for Indigenous Australians.
Clinical outcomes of pediatric cerebral cavernous malformation: an analysis of 124 consecutive cases
Authors: Shim Youngbo , Phi Ji Hoon , Wang Kyu-Chang , Cho Byung-Kyu , Lee Ji Yeoun , Koh Eun Jung , Kim Kyung Hyun , Lee Eun Jung , Kim Ki Joong , Kim Seung-Ki 
Published: September 2022

OBJECTIVE
One-fourth of cerebral cavernous malformation (CCM) patients are children, but studies on these patients are scarce. This study aimed to identify the clinical presentation of pediatric CCM patients and to investigate clinical outcomes according to the treatment modalities applied on the basis of our institution’s treatment strategy.

METHODS
The authors performed a retrospective analysis of 124 pediatric CCM patients with a follow-up of more than 1 year from 2000 to 2019. They performed resection (n = 62) on lesions causing intractable seizure, rebleeding, or mass effect and observed the clinical courses of patients with lesions in deep or eloquent areas without persistent symptoms (n = 52). Radiosurgery (n = 10) was performed when the patient refused resection or strongly desired radiosurgery. The authors investigated the clinical characteristics, performance status (modified Rankin Scale [mRS] score), and rebleeding rate at the 1-year and last follow-up examinations and compared these among 3 groups classified on the basis of treatment applied. The authors evaluated seizure outcomes at the 1-year and last follow-up examinations for the surgery (n = 32) and observation (n = 17) groups. Finally, the authors drew cumulative incidence curves for the discontinuation of antiepileptic drugs (AEDs) for patients in the surgery (n = 30) and observation (n = 9) groups.

RESULTS
The 3 groups showed slight differences in initial symptoms, lesion locations, and rates of recent hemorrhage. The proportion of patients with improved mRS score at the 1-year follow-up was significantly greater in the surgery group than in the other groups (67% of the surgery group, 52% observation group, and 40% radiosurgery group; p = 0.078), as well as at the last follow-up (73% surgery group, 54% observation group, and 60% radiosurgery group; p = 0.097). The surgery group also had the lowest rebleeding rate during the follow-up period (2% surgery group, 11% observation group, and 20% radiosurgery group; p = 0.021). At the 1-year follow-up, the proportion of seizure-free patients without AEDs was significantly higher in the surgery group than the observation group (88% surgery group vs 53% observation group, p < 0.001), and similar results were obtained at the last follow-up (91% surgery group vs 56% observation group, p = 0.05). The 5-year AED-free rates for the surgery and observation groups were 94% and 50%, respectively, on the cumulative incidence curve (p = 0.049).

CONCLUSIONS
The clinical presentation of pediatric CCM patients was not significantly different from that of adult patients. Lesionectomy may be acceptable for pediatric CCM patients with indications of persistent seizures despite AED medications, rebleeding, and mass effects.
POSISI PEREMPUAN DALAM ADAT PERNIKAHAN BUDAYA SUMBA DAN KORELASINYA DENGAN BUDAYA OSING DI BANYUWANGI DAN SASAK DI LOMBOK
Authors: Agust Amara Ridha Amalia 
Published: September 2022

Penelitian ini memiliki tujuan untuk mendeskripsikan tentang posisi perempuan dalam ada pernikahan budaya Sumba dan korelasinya dengan budaya Osing di Banyuwangi dan Ssak di Lombok. Adat pernikahan budaya Sumba diambil dari novel Perempuan yang Menangis Kepada Bulan Hitam. Teori yang digunkan adalah teori antropologi sosial srukturalisme dari Claude Levi-Strauss. Data pada penelitian ini adalah kalimat dan paragraph dari novel Perempuan yang Menangis Kepada Bulan Hitam. Teknik pengumpulan data yang digunakan adalah teknik kepustakaan. Sedangkan, analisis data menggunakan teknik analisis isi. Hasil dari penelitian ini 1) Posisi perempuan dalam adat pernikahan budaya Sumba yang sangat merugikan pihak perempuan, 2) Korelasi adat pernikahan budaya Sumba dengan adat pernikahan budaya Osing di Banyuwangi dan Sasak di Lombok.
Kata Kunci: adat penikahan, korelasi adat pernikahan, antropologi Levi-strauss
PENGARUH MODEL PEMBELAJARAN COOPERATIVE INTEGRATED READING AND COMPOSITION (CIRC) TERHADAP KEMAMPUAN MENULIS TEKS ULASAN PADA SISWA KELAS VIII SMP N 5 RANTAU BAYUR
Authors: Yanti Fitri , Missriani  , Darwin Effendi  
Published: September 2022

Dengan menggunakan model ini diharapkan menjadi alternatif dalam memecahkan masalah yang dihadapi oleh guru terhadap siswa yang merasa bosan dengan pembelajaran Bahasa Indonesia, terutama dalam keterampilan menulis pada siswa kelas VIII SMP N 5 Rantau Bayur terhadap sasaran penelitian yang dilakukan. Menggunakan metode kuantitatif eksperimen hasil yang didapat dari penelitian ini bahwa nilai rata-rata kelas eksperimen mencapai 83,5 dengan menggunakan perlakuan yang artinya sudah mencapai angka KKM, sedangkan rata-rata untuk kelas kontrol hanya 65,91 yang tidak mencapai KKM. Berdasarkan uji homogenitas data yang dilakukan didapatkan hasil F hitung sebesar 1,25 dan F tabel dengan taraf signifikansi 0,05 adalah 2,01, hal ini menunjukkan bahwa F hitung < F tabel sehingga dapat dikatakan bahwa data kedua varian ini homogen. Untuk pengujian hipotesis nya diperoleh t hitung 38,32 dan t tabel 1,678 ini menunjukkan bahwa t hitung > t tabel. Dapat dikatakan bahwa H0 ditolak dan Ha diterima. Hal ini menunjukkan bahwa ada pengaruh dari model pembelajaran Cooperative Integrated Reading and Composition (CIRC) terhadap menulis teks ulasan pada siswa kelas VIII SMP N 5 Rantau Bayur.
Kata Kunci : Model CIRC, Teks ulasan,Keterampilan Menulis
PENGEMBANGAN MODUL ELEKTRONIK PADA MATERI PUISI MATA PELAJARAN BAHASA INDONESIA SISWA KELAS X SMA BINA WARGA 1 PALEMBANG
Authors: Melly Melly Anggraini , Darwin Effendi  , Hetilaniar  
Published: September 2022

Penelitian ini bertujuan untuk mengembangkan modul elektronik pada materi puisi mata pelajaran bahasa Indonesia yang layak, valid dan praktis untuk pembelajaran siswa kelas X SMA Bina Warga 1 Palembang. Penelitian pengembangan ini menggunakan model Brog and Gall. Subjek uji coba penelitian ini adalah siswa SMA Bina Warga 1 Palembang kelas X dengan jumlah 27 siswa. Yang terdiri atas 6 siswa untuk uji coba lapangan skala kecil dan 27 siswa untuk uji coba lapangan skala besar. Hasil penelitian menunjukkan bahwa modul elektronik pada materi puisi pada aspek kelayakan materi berkategori sangat baik dengan persentase 93%, pada aspek kelayakan bahasa berkategori baik dengan persentase 76%, dan aspek kelayakan pada media berkategori dengan sangat baik dengan persentase 96,42%. Uji coba kelompok skala kecil mencapai nilai dengan persentase 88,95% berkategori sangat baik dan uji kelompok skala besar mencapai nilai persentase 90,6% dengan kategori sangat baik. Sehingga modul elektronik ini valid dan layak untuk dikembangkan.
Detection and Estimation of Heavy Metals in Broiler Meat Available in Lahore, Pakistan
Authors: Salamat Hira , Shahbaz Sana 
Published: September 2022

Cadmium (Cd) and lead (Pb) are toxic environmental pollutants. These heavy metals create serious health issues in consumers. The current study aimed to identify the quantity of lead and cadmium in broiler chicken, including in its liver and kidneys, since the demand for chicken meat as a food source is increasing day by day. Forty (40) broiler chickens were purchased from the various markets of Lahore, Pakistan including the markets of Sadar Cantt area, Shahdra, Alkarim park, Anarkali, and Muslim town. These chickens were collected, processed, and analyzed to determine the levels of lead and cadmium in their internal organs (liver and kidneys) using atomic absorption spectrophotometer. This process was carried out in the laboratory of PCSIR after the digestion of all samples via nitric acid (HNOз) and hydrogen peroxide using the wet digestion method. The range of the mean concentration of lead (4.50 - 8.50ug /g) and cadmium (25.00 - 27.75 ug/g) in the internal organs of broiler chicken exceeded the permissible level of 0.05% recommended by the World Health Organization (WHO). ANOVA analysis revealed that the presence of heavy metals was not significant in the internal organs of broiler meat collected from different areas of Lahore, since the p-value was greater than the significance level (p > 0.05). Hence, heavy metal concentrations were recorded as above the permissible level recommended by the WHO.
GIGANTIC ADRENAL CYST MIMICKING MESENTERIAL TUMOR: A CASE REPORT
Authors: Baskoro Ario , Caesar Khairul Walad  , Syamsu Hudaya  , Amrizal Umran  
Published: September 2022

Objective: This study aims to know the effects of giant adrenal cysts and their challenges for surgeons. Case(s) Presentation: A 41 years old female was referred with a chief complaint of growing palpable mass on the left side of the abdomen since five months ago. During the past five months, the patient has also had complaints of hard narrow-caliber stools. The general conditions and vital signs have been within normal limits. Discussion: Complete resection of the tissue remains the current best treatment of choice. When available, laparoscopic adrenalectomy is the gold standard for treating giant adrenal cysts. Open adrenalectomy is an alternative when laparoscopic adrenalectomy is not available, or when there is not enough diagnostic information preoperatively. For large cysts with a size of >6cm, open surgery is the favorable treatment, because it is difficult to control the mass via the laparoscopic approach. Conclusion: The giant adrenal cyst is a rare condition that, due to its size, it could lead to moderate-severe abdominal symptoms. Localizing the origin of the cysts preoperatively poses a challenge for surgeons and diagnosticians. Intraoperative diagnostic and therapeutic with laparoscopy or open surgery is recommended for these cases.
CHARACTERISTIC CHEMOTHERAPY RESPONSE OF TESTICULAR CANCER PATIENTS IN TERTIARY HOSPITAL
Authors: Fabrianta Dio Mafazi , Seputra Kurnia Penta , Daryanto Besut 
Published: September 2022

Objective: The purpose of this study was to determine the correlation of testicular tumor markers on the success of chemotherapy in my institution. Material & Methods: This research is a retrospective study single center using the medical record database at the span of the research period. The patient with testicular carcinoma who underwent complete chemotherapy between 2017 until 2022 was included. The data collected and analyzed by descriptive data and analytical correlation using SPSS Ver. 25. The comparation test using T-test and Anova. Results: A total of 31 testicular cancer patients were enrolled in the study. Fifteen patients were seminoma and 16 patients were non-seminoma. The mean age of patient at presentation of seminoma and non seminoma were 38.3 ± 17.03 and 30.74 ± 13.01. Most patients presented a karnofsky score about 79 ± 15. There was a negative correlation (r=-0.492) with a significant correlation between the types of testicular carcinoma cases and the response to chemotherapy (p=0.027). There was a significant difference in cases of seminoma and non-seminoma to the success of the chemotherapy response (p=0.024). There was a positive correlation between serum β-HCG, AFP, LDH with serial chemotherapy result with a no significant correlation (p=0.879; p=0.242; and p=0.277). Conclusion: Most types of the testicular carcinoma responses to chemotherapy. Patients with seminoma pathology have better response to chemotherapy compared to non-seminoma.