bluuebunny/crossref_metadata_2025_split huggingface dataset:
What is the correlation between Juvenile Idiopathic Arthritis and the image appearance of MRI, CT, and CBCT findings in TMJ? A systematic review
Authors: Hara Giovana Felipe , de Souza-Pinto Gustavo Nascimento , Brasil Danieli Moura , Poluha Rodrigo Lorenzi , Iwaki Lilian Cristina Vessoni , Iwaki-Filho Liogi , Haiter-Neto Francisco 
Published: August 2022

Abstract
Objective: To investigate the relation of the appearance of signs in the MRI, cone-beam computed tomography (CBCT), and conventional computed tomography (CT) images of TMJ from patients with JIA using conducting a systematic review.Materials and methods: Electronic searches in PubMed, Embase, Web of Science, Scopus, Lilacs, and The Cochrane Library were conducted to identify studies investigating JIA and imaging findings. Inclusion criteria were: original articles studies based on humans and systematic reviews, studies enrolling patients with less than 18 years with diagnostic of JIA, use of ILAR criteria and one type of image exam (MRI, CBCT, or CT), and papers in the English language.Results: Six studies fulfill the eligibility criteria: four used MRI and two CBCT and all analyzed imaging findings in pathological TMJ with JIA. The results showed that enhancement of the synovial membrane, condylar erosions, and flattening are the most prevalent imaging findings of JIA.Conclusion: MRI exams are more specific in anomaly detection in TMJ in comparison to CBCT and CT. Also, the results must be correlated to clinical signs to provide a correct diagnosis.Clinical Relevance: This study indicates the most prevalent imaginological signs of JIA to provide early and correct diagnosis for the disease.
Stability Analysis of Periodic Solutions of Bonhoeffer Van-der-pol System With Applied Impulse
Authors: Eze Everestus Obinwanne , Obasi Uchenna Emmanuel , Urama Thomas 
Published: August 2022

Abstract
In this paper, the stability analysis of periodic solutions of Bonhoeffer Van der Pol system with applied impulse was investigated using Lyapunov direct method. Through the use of appropriate values of the control parameters, three equilibria points and periodic solutions of the system were obtained. A Lyapunov candidates which depended on the parameters were constructed. Hence, we concluded that the equilibria points have different regions of stability and instability of the system in which the two regions were found to be stable. Furthermore, Mathcad software was used to analyze the behavior of the system, thereby improving known results in literature.Mathematics Subject Classification (2010): 34B15, 34C15, 34C25, 34K13
Contrast Enhanced Computed Tomographic Evaluation of Coeliac, Hepatic and Superior Mesenteric Arterial Variants
Authors: Johny Jovis , K Shreyas Reddy , George Arun , S Nidhi , Philip Babu 
Published: August 2022

Abstract
Purpose: With the advent of new hepato-biliary interventions, preoperative assessment of coeliac, hepatic, and mesenteric arterial anatomy has now become a necessity for surgeons and interventional radiologists. The primary aim is to avoid or minimize the ischemic complications that could occur during surgeries such as liver transplants, abdominal interventions etc. This study was undertaken to evaluate the variants in coeliac, hepatic, and superior mesenteric arteries based on CECT abdomen. Methods: A prospective study was conducted over a period of 2 years (2020- 2021) on 388 patients who underwent CECT abdomen for evaluation of the above-mentioned variants.Results: 14 types of CM trunk and 11 types of hepatic artery variants were identified in this study. Anatomical variations in CM trunk and CHA were seen in 6.4 % and 7.7 % respectively. The average diameter of the coeliac artery was found to be 6.6 mm, common hepatic artery was 5.04 mm and superior mesenteric trunk was 6.6 mm. In cases with variant coeliac -SMA axis, the average diameter of the coeliac trunk was 5.7 mm while the average arterial diameter of the hepatic artery in CHA variants was 4.38 mm.The pathological variations found in the study were: MALS/ Dunbar syndrome, SMA compression syndrome, aortoarteritis and nutcracker syndrome.Significant correlation was noted between presence of CHA and coeliac -SMA axis variations i.e., the patients with CHA variation were 3.38 times more likely to have coeliac-mesenteric arterial variation.The diameters of common hepatic and coeliac artery was noted to be reduced in cases with anatomical variations (p < 0.05). CONCLUSION - There is an association of coeliac -mesenteric artery variations with common hepatic arterial variations. Another correlation was found between the arterial diameters in cases with variant anatomy versus normal cases in the study population. No significant association between pathological variants like median arcuate ligament syndrome, SMA compression syndrome etc. with normal hepatic /CM trunk variations.Attempt was also made to describe the newly found variations in these target vessels, not previously characterized in the standard classification system.
Chemical Reaction and Viscous Dissipative Effects on Buongiorno’s Nanofluid Model Past an Inclined Plane
Authors: Reddy Sivaram , Gaffar S. Abdul 
Published: August 2022

Abstract
Nanofluid thermal usage has considerably enhanced heat and mass transfer characteristics, which are critical across various engineering industries. Numerous dynamic applications in renewable energy and thermodynamic engineering issues benefit from the study of nanofluids. In this paper we discuss the chemically viscous dissipative transport of Buongiorno’s nanofluid across an inclined plane considering the Brownian movement and thermophoresis effects. The governing equations and the related boundary conditions are normalized using the non-similarity transformation approach, and the relevant variables and corresponding non-similarity solutions are shown to summarize the transpiration parameters. The mathematical solutions are obtained using the Keller’s Box technique. For various thermo-physical parameter values, the numeric results are provided both physically and quantitatively. The graphical impacts of different thermos physical factors on momentum, energy, nanoparticle volume fraction concentration, skin friction, local Nusselt number and local Sherwood number are examined and well argued. The outcomes are well associated when compared to previously published literature.
Acetyltransferase NAT10 regulates the Wnt/β-catenin signaling pathway to promote colorectal cancer progression via ac4C acetylation of KIF23 mRNA NAT10 promotes CRC progression
Authors: Jin Chi , Wang Tuo , Yang Peng , Zhang Chuan , Peng Wen , Zhang Dongsheng , Jin Kangpeng , Wang Lu , Zhou Jiahui , Peng Chaofan , Tan Yuqian , Ji Jiangzhou , Chen Zhihao , Sun Qingyang , Yang Sheng , Tang Junwei , Feng Yifei , Sun Yueming 
Published: August 2022

Abstract
Background: N4-acetylcytidine (ac4C) as a significant RNA modification has been reported to maintain the stability of mRNA and to regulate the translation process. However, the roles of both ac4C and its ‘writer’ protein N-acetyltransferase 10 (NAT10) played in the disease especially colorectal cancer (CRC) are unclear. At this point, we discover the underlying mechanism of NAT10 modulating the progression of CRC via mRNA ac4C modification.Methods: The clinical significance of NAT10 was explored based on the TCGA and GEO data sets and the 80 CRC patients cohort of our hospital. qRT-PCR, dot blot, WB and IHC were performed to detect the level of NAT10 and ac4C modification in CRC tissues and matched adjacent tissues. CCK-8, colony formation, transwell assay, mouse xenograft and other in vivo and in vitro experiments were conducted to probe the biological functions of NAT10. The potential mechanisms of NAT10 in CRC were clarified by RNA-seq, RIP-seq, acRIP-seq, luciferase reporter assays, etc. Results: The levels of NAT10 and ac4C modification were significantly upregulated. Also, the high expression of NAT10 had important clinical values like poor prognosis, lymph node metastasis, distant metastasis, etc. Furthermore, the in vitro experiments showed that NAT10 could inhibit apoptosis and enhance the proliferation, migration and invasion of CRC cells and also arrest them in the G2/M phase. The in vivo experiments discovered that NAT10 could promote tumor growth and liver/lung metastasis. In terms of mechanism, NAT10 could mediate the stability of KIF23 mRNA by binding to its mRNA 3’UTR region and up-regulating its mRNA ac4c modification. And then the protein level of KIF23 was elevated to activate the Wnt/β-catenin pathway and more β-catenin was transported into the nucleus which led to the CRC progression. Besides, the inhibitor of NAT10, remodelin, was applied in vitro and vivo which showed an inhibitory effect on the CRC cells.Conclusions: NAT10 promotes the CRC progression through the NAT10/KIF23/GSK-3β/β-catenin axis and its expression is mediated by GSK-3β which forms a feedback loop. Our findings provide a potential prognosis or therapeutic target for CRC and remodelin deserves more attention.
Role of International Academy of Cytology Yokohama reporting system in breast lesions at a tertiary care center in Central India
Authors: Verma Deepshikha , khademi Nilufar , Mahabadi Mohammadjavad Ashrafi , Newaskar Vedanti , Balani Sharda , Malik Reeni , Khan Arshi 
Published: August 2022

Abstract
Background: The International Academy of Cytology (IAC) Yokohama System to report breast cytopathology can effectively categorize breast diseases into different cytological groups. Fine needle aspiration (FNAC) from the lesions in the breast has been regarded as an effective method of diagnosing breast cancer, particularly in rural settings. The principal purpose of this study was to validate the diagnostic accuracy of breast FNA utilizing the IAC Yokohama system in future endurances. Histopathological evaluation was also performed to corroborate the correctness of the FNA of the breast.Methods: Research on patients getting core-needle/incisional/excisional biopsy of breast lesions between January 1st, 2021, and December 31st, 2021, was conducted at a tertiary care center in central India. 216 breast FNAs were recorded utilizing the IAC Yokohama system, and the most appropriate category was assigned for every case.Results: The new “International Academy of Cytology (IAC) Yokohama system” was used to categorize 216 patients into five categories based on the cytologic diagnosis. That C1: insufficient material (8.7%), C2: benign (65.7%), C3: atypical (1.8%), C4: suspicious of malignancy (2.7%), and C5: malignant (20.8%). To examine diagnostic accuracy, FNACs were associated with ancillary testing and histological diagnosis. The overall specificity, sensitivity, negative predictive value, and positive predictive value, along with the accuracy, were calculated with the risk of malignancyConclusion: With high specificity and sensitivity, for each type of situation, for all tumors, and each analyzed BIRADS category show that the IAC Yokohama system provides excellent accuracy for Breast FNA.
Quality Assurance Awareness in Higher Education in China: Big Data Challenges
Authors: Zhang Ruihua , Zhou Jincheng , Hai Tao , Zhang Shixue , Iwendi Marvellous , Biamba Cresantus , Anumbe Noble 
Published: August 2022

Abstract
The quality assurance of higher education in China is an issue of vital international interest. To improve the international reputation of the nation’s universities, steps must be taken to ensure a sustained focus on the quality assurance within its ranks. This paper is primarily focused on the quality assurance models operational in Chinese universities, the Big data challenges and the legal framework backing them. The paper also discusses the implementation of the models, the extent to which they meet international standards, and how they adhere to prevailing laws. The degree of success in attaining and maintaining quality and evaluation of quality improvement opportunities are also discussed. Some of the solutions recommended in this study are the participation of more teachers and students in quality management, more emphasis of Higher Education Institution (HEI) quality assurance on self-regulation and a learning-oriented approach and conducting sessions to collect anonymous feedback from students to reward staff with best practices. Some of the Quality Assurance practices/models adopted in Chinese Universities are the Ministry of Education (MOE) reviews; the Academic Degree Committee oversight; Higher Education Evaluation Center (HEEC) overview, University self-evaluation according to the HEEC Table 1 Indicators, and the Webometric Ranking Model.
Behavior of Energy Ratios Under Higher-order Mdd at Distinct Media
Authors: Barak M. S. , Kumar Rajesh , Kumar Rajneesh , Gupta Vipin 
Published: August 2022

Abstract
This paper presents a novel mathematical model of orthotropic piezothermoelastic half-space under the reference of three-phase lags heat transfer law with higher-order memory-dependent derivatives (HPS) underlying a thermoelastic half-space (TS). Thermoelastic plane waves involving longitudinal P wave, thermal T wave, or transversal SV wave propagating via TS medium and hitting at the interface x3 =0 results in three waves reflected in the TS medium and four waves transmitted in the HPS medium. Amplitude ratios are determined at the boundary interface x3 =0 and used to obtain the energy ratios of various reflected and transmitted waves. It is noticed that these ratios are under the impact of phase lags, higher order MDD parameters, frequency of the waves, and other physical parameters involved in the model. The balance law of energy conservation is justified. Graphically illustrated the impact of higher order memory-dependent derivatives parameters on the energy ratios variation with the incidence angle. Some unique cases of interest are also deduced
40 years of adding more fructose to high fructose corn syrup than is safe, through the lens of malabsorption and altered gut health–gateways to chronic disease
Authors: DeChristopher Luanne Robalo 
Published: August 2022

Abstract
Labels do not disclose the excess-free-fructose content in foods/beverages. Objective was to estimate excess-free-fructose intake using USDA loss-adjusted-food-availability data (1970-2019) for high fructose corn syrup (HFCS) and apple juice, major sources of unpaired fructose, for comparison with malabsorption dosages (~5g-children/~10g-adults). Daily intakes were calculated for HFCS that is generally-recognized-as-safe/(55% fructose/45% glucose), and variants (65/35, 60/40) with higher fructose-to-glucose ratios (1.9:1, 1.5:1), as measured by independent laboratories. Estimations include consumer-level-loss (CLL) allowances used before (20%), and after, subjective, retroactively-applied increases (34%), as recommended by corn-refiners (~2012).ResultsExcess-free-fructose daily intake for individuals consuming HFCS with an average 1.5:1 fructose-to-glucose ratio, ranged from 0.10 g/d in 1970, to 11.3 g/d in 1999, to 6.5 g/d in 2019, and for those consuming HFCS with an average 1.9:1 ratio, intakes ranged from 0.13 g/d to 16.9 g/d (1999), to 9.7 g/d in 2019, based upon estimates with a 20% CLL allowance. Intake exceeded dosages that trigger malabsorption (~5 g) around ~1980. By the early 1980’s, the tripling of apple juice intake, had added ~0.5 grams to average-per-capita excess-free-fructose intake. Contributions were higher (3.8 g /4-oz.) for individuals consuming apple juice consistent with a healthy eating pattern (4-oz. children, 8-oz. adults). This analysis did not account for contributions from crystalline fructose or agave syrup.ConclusionThe displacement of sucrose with HFCS, its ubiquitous presence in the US food supply, and industry practice of adding more fructose to HFCS than generally-recognized-as-safe, have contributed to unprecedented excess-free-fructose daily intake levels, malabsorption, gut dysbiosis and associated chronic disease.
The Security Implication of Neglecting Tourist Attractions in Nigeria: A Case Study of Zuma Rock
Authors: Mshelia Isma'il Husain , Kpada Rakiya Yusuf , Jeffrey Usman Salami 
Published: August 2022

Abstract
As tourism becomes one of the industries generating huge revenue for the governments of many countries, Nigeria is yet to follow suit with many man-made and natural tourist attractions suffering from wanton neglect. This study examined the security implications of neglecting tourism in Nigeria with specific focus on Zuma Rock. Media reports examined revealed that the vicinity of the rock, being too uncared for, aids the occurrence of criminal acts such as armed robbery, bike snatching, drug dealing, sexual assaults and murder. A total of 384 respondents across five communities surrounding the Zuma Rock were surveyed. The study found that the residents of the communities live in fear due to not only the prevalence of violent crimes in the vicinity of the rock but also lack of belief in the effort of the formal social control agents. It is therefore recommended that the government should develop the destination while the residents should develop effective informal social control methods.
Transaminases’’ characteristics among consumers of indigenous alcohol ''Lutuku'' and no consumers in Lubumbashi
Authors: Diyoka Chadrack Kabeya , Kabwebwe Honoré Mitonga , Omba Isabelle Kasongo , Ndwayi Denis Ngokweyi , B.B. Victor Ndibualonji , Mjumbe Criss Koba 
Published: August 2022

Abstract
Background: The lack of knowledge of the biochemical processes in the treatment process of Lutuku constitutes a real problem. The study compares the enzymatic activity of transaminases in consumers of native Lutuku alcohol and non-consumers.Methods: This is a case-control study involving 40 Lutuku-consuming and healthy subjects. The enzymatic activities of GOT and GTP were performed using standard clinical chemical methods developed by BIOLAB.Results: The rate of TGO and TGP are 4 to 5 times higher in consumers of Lutuku than in healthy subjects. In the control group, the median TGO/TGP serum ratio was more pronounced in women (0.9667 U/l) than in men (0.88 U/l). Female alcoholics had a serum TGO/TGP ratio of 1, while males had a median ratio of 1.0275. Serum GOT/GTP ratios were correlated with serum GOT in both sex with respectively (r = 0.268 , p < 0.01) in men and (r= 0.499, p < 0.05) in women; and GTP (r = 0.236 , p < 0.01 ) only in men.Conclusion: Consumption of Lutuku induced four to five times more transaminase activities (TGO and TGP) compared to those observed in healthy.
Marketing and Organizational Innovations in Europe
Authors: Costantiello Alberto , Laureti Lucio , Leogrande Angelo 
Published: August 2022

Abstract

In this article we investigate the determinants of marketing or organizational innovators in Europe for 36 countries in the period 2010-2019. We have used data from the European Innovation Scoreboard-EIS of the European Commission. We perform different econometric models i.e. Dynamic Panel, Pooled OLS, Panel Data with Fixed Effects, Panel Data with Random Effects, WLS. Results show that the level of marketing or organizational innovators in positively associated, among others variables to “Innovation Index”, “Innovators” and “Knowledge Intensive Service Exports”, while is negatively associated with “Sales Impacts”, “Foreign Controlled Enterprises Share of Value Added” and “Government procurement of advanced technology products”.
Urgensi Nilai-nilai Pendidikan Karakter dalam Kitab Al-Arba’īn Al-Nawawiyyah bagi Perkembangan Kualitas Pendidikan Indonesia
Authors: Muntakhib Ahmad 
Published: August 2022

Education is the most effective method for the internalization of character values. The most applicable character values are the values in the hadith of Muhammad. one of the books that discuss the hadith of the Prophet is the book of Al-Arba'īn al-Nawawiyyah. This study is intended to discuss what are the values of character education in Kitab Al-Arba'īn al-Nawawiyyah. Hadiths in Al-Arba'īn al-Nawawiyyah have been analyzed by using content analysis with hermeneutic method. Studies show that the book Al-Arba'īn al-Nawawiyyah contains the values of character education that emphasize the human relationship with God, either directly or indirectly. The values of character education contained in the book Al-Arba'īn al-Nawawiyyah include: obedient, able to control oneself, leave something dubious, have shame, leave useless deeds, love fellow Muslims like love himself, keep oral and glorify neighbors and guests, believe and istiqamah, zuhd, and do not procrastinate the work.* * *Pendidikan merupakan metode paling efektif untuk internalisasi nilai-nilai karakter. Nilai-nilai karakter yang paling aplikatif adalah nilai-nilai dalam hadis nabi Muhammad. salah satunya kitab yang membahas hadis nabi adalah kitab Al-Arba’īn al-Nawawiyyah. Kajian ini dimaksudkan untuk membahas apa saja nilai-nilai pendidikan karakter dalam Kitab Al-Arba’īn al-Nawawiyyah. Hadis-hadis dalam kitab Al-Arba’īn al-Nawawiyyah telah dianalisis dengan menggunakan content analysis dengan metode hermeneutik. Kajian menunjukkan bahwa kitab Al-Arba’īn al-Nawawiyyah mengandung nilai-nilai pendidikan karakter yang menekankan pada hubungan manusia dengan Allah, baik secara langsung maupun tidak langsung. Nilai-nilai pendidikan karakter yang terkandung dalam kitab Al-Arba’īn al-Nawawiyyah meliputi: taat, mampu mengendalikan diri, meninggalkan sesuatu yang meragukan, mempunyai rasa malu, meninggalkan perbuatan yang tidak berguna, mencintai sesama muslim seperti mencintai dirinya sendiri, menjaga lisan dan memuliakan tetangga dan tamu, beriman dan istiqomah, zuhud, dan tidak menunda-nunda pekerjaan.
Media dan Demokrasi di Era Global: Studi Dakwah Islam Kontemporer di Indonesia
Authors: Rachmawati Farida 
Published: August 2022

Globalization has affected all the cultural subsystems of today's society, especially in media. How Islamic da’wa opportunities in the midst of media globalization is the focus of this article. Library studies have been used in this study. The result shows that Islamic da’wa is in the marginal position and has not been able to become a major player. There are four opportunities that can be used in preaching Islam in the era of media globalization. First, the freedom of information media is filled with enhancing creativity in making Islamic content more interesting and reflecting Islam's rahmatan lil 'alamin. Secondly, Islamic missionary media participated in the formation of public opinion. Third, the education of Muslims based on morality. Muslims must be faithful to the teachings of religion and consistent with the religious ideal. Fourth, to maximize the source of Islamic capitalism such as zakat, as a tool to achieve the welfare of all people.* * *Globalisasi telah memengaruhi semua subsistem budaya masyarakat saat ini, terlebih di bidang media. Bagaimana peluang dakwah Islam di tengah globalisasi media merupakan fokus dari artikel ini. Studi kepustakaan telah digunakan dalam penelitian ini. Hasilnya menunjukkan bahwa posisi dakwah Islam berada di posisi terpinggirkan dan belum mampu menjadi pemain utama. Terdapat empat peluang yang bisa digunakan dalam berdakwah Islam di era globalisasi media. Pertama, kebebasan media informasi diisi dengan meningkatkan kreativitas dalam membuat konten-konten Islami yang lebih menarik dan mencerminkan Islam rahmatan lil ‘alamin. Kedua, media dakwah Islam Ikut serta menjadi pemain dalam pembentukan opini publik. Ketiga, pendidikan umat Islam berbasis moralitas. Muslim harus setia pada ajaran agama dan konsisten terhadap idealitas agama. Keempat, mendayagunakan secara maksimal sumber kapitalisme Islam seperti zakat, sebagai alat untuk mencapai kesejahteraan seluruh umat.