bluuebunny/crossref_metadata_2025_split huggingface dataset:
Visits of concern in child neurology telemedicine
Authors: Prelack Marisa , Fridinger Sara , Gonzalez Alexander K. , Kaufman Michael C. , Xian Julie , Galer Peter D. , Craig Sansanee , Abend Nicholas S. , Helbig Ingo ,   CHOP Neuroscience Center – VOC Research Group*
Published: May 2022

AbstractAimTo characterize child neurology telemedicine visits flagged as requiring in‐person evaluation during the COVID‐19 pandemic.MethodWe analyzed 7130 audio‐video telemedicine visits between March and November 2020. Visits of concern (VOCs) were defined as telemedicine visits where the clinical scenario necessitated in‐person follow‐up evaluation sooner than if the visit had been conducted in‐person.ResultsVOCs occurred in 5% (333/7130) of visits for 292 individuals (148 females, 144 males). Providers noted technical challenges more often in VOCs (40%; 133/333) than visits without concern (non‐VOCs) (28%; 1922/6797) (p < 0.05). The median age was younger in VOCs (9 years 3 months, interquartile range [IQR] 2 years 0 months–14 years 3 months) than non‐VOCs (11 years 3 months, IQR 5 years 10 months–15 years 10 months) (p < 0.05). Median household income was lower for patients with VOCs ($74 K, IQR $55 K–$97 K) compared to non‐VOCs ($80 K, IQR $61 K–$100 K) (p < 0.05). Compared with all other race categories, families who self‐identified as Black were more likely to have a VOC (odds ratio 1.53, 95% confidence interval 1.21–2.06). Epilepsy and headache represented the highest percentages of VOCs, while neuromuscular disorders and developmental delay had a higher proportion of VOCs than other neurological disorders.InterpretationThese findings suggest that telemedicine is an effective platform for most child neurology visits. Younger children and those with neuromuscular disorders or developmental delays are more likely to require in‐person evaluation.What this paper adds

It is possible to successfully flag patients who need in‐person assessment.

Providers can manage issues arising during telemedicine in 95% of visits.

Visits flagged as concerning were likely unrelated to modality of patient care.

Provider concern was independent of technical difficulties for most telehealth visits.

Younger age may be correlated with need for in‐person assessment.
The effect of the conceptual metaphor theory on the teaching of orientation idioms in teaching Turkish as a foreign language
Authors: Karatay Halit , Kartallıoğlu Nurettin , Zorpuzan Sena Sapmaz , Tezel Kadir Vefa 
Published: May 2022

The ChallengeLearners who attend a foreign language course aim to learn the lexis and grammar of that language and develop their basic language skills. Does this mean that idioms which are among the essential elements of any language are taught at a satisfactory level to learners? Can learners be taught a strategy that would enable them to guess the meanings of unknown idioms in the contexts they are used? This article presents the results of a study that developed activities to teach idioms that contained orientation metaphors and incorporated them into a language program.
“When nobody listens, go online”: The “807” labor movement against workplace sexism in China's tech industry
Authors: Liu Hong Yu 
Published: May 2022

AbstractAn online petition, signed by more than six thousand Chinese tech workers in August 2021, is the latest example of an online labor movement in the authoritarian context of China. Combining interviews and publicly available information, this article provides a descriptive account of an activist movement, explains workers' demands, and discusses the characteristics of online labor activism. It explores how Chinese tech workers fight collectively against a gender‐discriminatory workplace culture as they strive to bring justice to a sexual crime victim without affiliating themselves with official political organizations. The research findings suggest that while rising feminist consciousness has the potential to motivate collective action by workers, such motivation is highly dependent upon individual experiences at work and tends to be event‐based and of limited continuity. It argues that rising awareness of women's rights provides a new kind of legitimacy to labor activism, and a new way to express labor concerns in a context of increased criminalization of labor organizational activities in China today.
Acquired bleeding disorders
Authors: Tiede Andreas , Zieger Barbara , Lisman Ton 
Published: May 2022

AbstractAcquired bleeding disorders can accompany hematological, neoplastic, autoimmune, cardiovascular or liver diseases, but can sometimes also arise spontaneously. They can manifest as single factor deficiencies or as complex hemostatic abnormalities. This review addresses (a) acquired hemophilia A, an autoimmune disorder characterized by inhibitory autoantibodies against coagulation factor VIII; (b) acquired von Willebrand syndrome in patients with cardiovascular disorders, where shear stress abnormalities result in destruction of von Willebrand factor; and (c) liver function disorders that comprise complex changes in pro‐ and anti‐hemostatic factors, whose clinical implications are often difficult to predict. The article provides an overview on the pathophysiology, diagnostic tests and state‐of‐the‐art treatment strategies.
Attitudes towards the integration of smoking cessation into lung cancer screening in the United Kingdom: A qualitative study of individuals eligible to attend
Authors: Groves Samantha , McCutchan Grace , Quaife Samantha L. , Murray Rachael L. , Ostroff Jamie S. , Brain Kate , Crosbie Philip A. J. , Yorke Janelle , Baldwin David , Field John K. , McWilliams Lorna 
Published: May 2022

AbstractIntroductionThere is limited research exploring how smoking cessation treatment should be implemented into lung cancer screening in the United Kingdom. This study aimed to understand attitudes and preferences regarding the integration of smoking cessation support within lung cancer screening from the perspective of those eligible.MethodsThirty‐one lung cancer screening eligible individuals aged 55–80 years with current or former smoking histories were recruited using community outreach and social media. Two focus groups (three participants each) and 25 individual telephone interviews were conducted. Data were analysed using the framework approach to thematic analysis.ResultsThree themes were generated: (1) bringing lung cancer closer to home, where screening was viewed as providing an opportunity to motivate smoking cessation, depending on perceived personal risk and screening result; (2) a sensitive approach to cessation with the uptake of cessation support considered to be largely dependent on screening practitioners' communication style and expectations of stigma and (3) creating an equitable service that focuses on ease of access as a key determinant of uptake, where integrating cessation within the screening appointment may sustain increased quit motivation and prevent loss to follow‐up.ConclusionsThe integration of smoking cessation into lung cancer screening was viewed positively by those eligible to attend. Screening appointments providing personalized lung health information may increase cessation motivation. Services should proactively support participants with possible fatalistic views regarding risk and decreased cessation motivation upon receiving a good screening result. To increase engagement in cessation, services need to be person‐centred.Patient or Public ContributionThis study has included patient and public involvement throughout, including input regarding study design, research materials, recruitment strategies and research summaries.
Higher plasma renin activity is associated with increased kidney damage risk in patients with hypertension and glucose metabolic disorders
Authors: Lin Mengyue , Heizhati Mulalibieke , Gan Lin , Hong Jing , Wu Ting , Xiamili Zuhere , Tong Ling , Lin Yue , Li Nanfang 
Published: May 2022

AbstractThe impact of renin on kidney remain unclear among hypertensives with glucose metabolic disorders (GMD). We aimed to evaluate the association between plasma renin activity (PRA) and kidney damage in hypertensive patients with GMD. Overall, 2033 inpatients with hypertension and GMD free of chronic kidney disease (CKD) at baseline were included. CKD was defined using estimated glomerular filtration rate (eGFR) and urine protein. PRA was treated as continuous variable, and also dichotomized as high (≥0.65) or low (< 0.65) groups. The association of PRA with incident CKD was evaluated using multivariable Cox model controlling for antihypertensive medications and baseline aldosterone, and traditional parameters. Subgroup and interaction analyses were performed to evaluate heterogeneity. During a median follow‐up of 31 months, 291 participants developed CKD. The incidence was higher in high‐renin group than that in low‐renin group (54.6 vs 36.6/1000 person‐years). Significant association was observed between PRA and incident CKD, and the association was mainly driven by an increased risk for proteinuria. Each standard deviation increment in log‐transformed PRA was associated with 16.7% increased risk of proteinuria (hazard ratio = 1.167,P = .03); compared with low‐renin group, there was 78.4% increased risk for high‐renin group (hazard ratio = 1.784,P = .001). Nonlinear associations were observed between PRA and kidney damage. Higher PRA is associated with greater risk of incident kidney damage, especially for positive proteinuria, in patients with coexistence of hypertension and diabetes, independent of aldosterone. In this patient population with high risk for kidney damage, PRA may serve as an important predictor.
Involving adolescents with intellectual disability in the adaptation of self‐reported subjective well‐being measures: participatory research and methodological considerations
Authors: Davison J. , Maguire S. , McLaughlin M. , Simms V. 
Published: May 2022

AbstractBackgroundThe measurement of subjective well‐being is challenging with samples of adolescents with intellectual disability (ID) given the cognitive and linguistic difficulties they face in comprehending standardised measures, and as such is primarily based on proxy reports. The lack of appropriate tools needs to be addressed so that adolescents with ID can self‐report on their own well‐being. The current study reports on the use of participatory research methods to adapt and modify two standardised self‐report measures of subjective well‐being suitable for completion by adolescents with ID.MethodTwo special schools were recruited for this study. At each school, staff (n = 15) and pupils aged 11–17 years (n = 35) participated. A series of co‐design workshops were conducted to adapt two standardised subjective well‐being measures: Kidscreen‐10 and short‐form Warwick–Edinburgh Mental Well‐being Scale.ResultsSpecific aspects for measure adaption were identified: simplifying the item wording and phrasing; inclusion of pictorial communication symbols and visual prompts to represent the meaning of items; changing of tense of questions from past to present; asking questions rather than statements; reducing 5‐point Likert scales to 3‐point or dichotomous; presenting one item at a time during administration; and developing alternate formats of the survey to ensure inclusivity.ConclusionsThis paper illustrates the value of using participatory research methods when working alongside adolescents with ID and offers methodological, as well as practical, guidance in the context of adapting subjective self‐report measures for this target group, serving as a guide to fellow researchers and clinicians interested in modifying or developing self‐report measures for adolescents with ID.
Breastfeeding and Human Lactation Curriculum Survey of Midwifery Programs in the United States
Authors: Webber Elaine , Wodwaski Nadine , Busch Deborah 
Published: May 2022

IntroductionThe health attributes and advantages of breastfeeding are well documented in the literature. Current research identifies the importance of comprehensive lactation knowledge among health care professionals to improve breastfeeding outcomes. Educational curricula to incorporate lactation content is necessary for student preparedness to provide competent care. Midwives are in a unique position to support, promote, and manage breastfeeding. The purpose of this study was to survey Accreditation Commission for Midwifery Education (ACME)‐accredited midwifery education programs in the United States for their breastfeeding curricular content including opportunities for clinical experiences in managing and counseling breastfeeding parents.MethodsA descriptive survey was deployed online to midwifery programs listed by the American College of Nurse‐Midwives, with a response completion rate of 44.7%. Data collection included program descriptors, hours of lactation content, educational topics, faculty preparation, use of simulation, and clinical breastfeeding experiences.ResultsDescriptive analyses revealed differences among the midwifery education programs surveyed regarding the amount of lactation content and clinical opportunities. Two programs offer a course specific to breastfeeding, with the remaining programs providing lactation content threaded throughout their curricula; 29.4% of programs offer 3 to 4 hours of lactation content, 35.3% report 5 to 8 hours of content, and 11.8% provide at least 10 hours of content. One program reports 18+ hours of content provided in both didactic and clinical settings. All programs report providing breastfeeding clinical opportunities for students; 18% of programs offer simulation experiences. No programs report using standardized lactation clinical competencies.DiscussionMidwives play a pivotal role in breastfeeding promotion, counseling, and clinical support. Standardization of didactic lactation education will assist programs in future curriculum mapping. Given the variability of clinical settings and patient access, creating clinical competencies and providing lactation simulation experiences may offer midwifery students a broader opportunity to gain critical skills in lactation management to best support breastfeeding families.
Leveraging protections, navigating punishments: How adult children of undocumented immigrants mediate illegality in Latinx families
Authors: Delgado Vanessa 
Published: May 2022

AbstractObjectiveThe objective of this study is to examine how adult children of undocumented immigrants manage parental illegality in Latinx immigrant families.BackgroundThere are 16.7 million people who live with at least one undocumented family member in the U.S. today. Scholars have documented how children of undocumented immigrants can help navigate the negative consequences of illegality in their families. However, less is known about how the immigration status of these youth shapes the support they provide to their undocumented parents.MethodThis study draws on 41 in‐depth semi‐structured interviews with 19 DACAmented and 22 U.S.‐born citizen college students (18–27) who had at least one undocumented parent. Interviews were collected via snowball sampling technique at a large research university in Southern California.ResultsThe findings suggest that citizen and DACAmented college students engage in distinct strategies when mediating illegality for their undocumented parents. Citizens attempt to leverage their protected legal status to help their undocumented parents become Lawful Permanent Residents and step in during situations where threats of deportation are imminent. DACAmented young adults draw on their experience with legal precarity to help their undocumented parents navigate punishments associated with their immigration status.ConclusionThis research uncovers how parents' precarious legal status contributes to the intergenerational transmission of disadvantage among citizen and DACAmented young adults—and how these youths try to mediate the harms of illegality.ImplicationsThe strategies adult children of undocumented immigrants implement to negotiate illegality in their families highlights the need for policy addressing the legal vulnerability of undocumented and mixed status families.
Impact of rural hospital closures on hospitalizations and associated outcomes for ambulatory and emergency care sensitive conditions
Authors: Khushalani Jaya S. , Holmes Mark , Song Suhang , Arifkhanova Aziza , Randolph Randy , Thomas Sharita , Hall Diane M. 
Published: May 2022

AbstractPurposeThe purpose of this paper is to examine the impact of rural hospital closures on age‐adjusted hospitalization rates for ambulatory care sensitive condition (ACSC) and emergency care sensitive condition (ECSC) and associated outcomes, such as length of stay and in‐hospital mortality in hospital service areas (HSAs) that utilized the closed hospital.MethodsWe used the State Inpatient Data from the Healthcare Cost and Utilization Project for 9 states from 2010 to 2017 and classified admissions as ACSC or ECSC. We compared age‐adjusted admission rates and length of stay (LOS) for ACSC and ECSC rates and age adjusted in‐hospital mortality rate for ECSC among rural ZIP codes in HSAs with a closure to rural ZIP codes in HSAs without closures. We used propensity score‐weighted regression analysis and event study design.FindingsFindings suggest that ACSC admission rates started to increase right before the closure. However, this increase levels off 2 years after closure. LOS for ACSC significantly decreased almost a year after closure. ECSC admissions showed a significant decrease for a few quarters 1 year before the closure.ConclusionsRural hospital closures were associated with increase in ACSC admissions right before closure and for nearly 2 years post closure as well as decrease in ECSC admissions before closure. As rural hospitals continue to close, efforts to ensure communities affected by these closures maintain access to primary health care may help eliminate increases in costly preventable hospital admissions for ACSC while ensuring access for emergency care services.
GmTDN1 improves wheat yields by inducing dual tolerance to both drought and low‐N stress
Authors: Zhou Yongbin , Liu Jun , Guo Jinkao , Wang Yanxia , Ji Hutai , Chu Xiusheng , Xiao Kai , Qi Xueli , Hu Lin , Li Hui , Hu Mengyun , Tang Wensi , Yan Jiji , Yan Huishu , Bai Xinxuan , Ge Linhao , Lyu Mingjie , Chen Jun , Xu Zhaoshi , Chen Ming , Ma Youzhi 
Published: May 2022

SummaryGenetically enhancing drought tolerance and nutrient use efficacy enables sustainable and stable wheat production in drought‐prone areas exposed to water shortages and low soil fertility, due to global warming and declining natural resources. In this study, wheat plants, exhibiting improved drought tolerance and N‐use efficacy, were developed by introducing GmTDN1, a gene encoding a DREB‐like transcription factor, into two modern winter wheat varieties, cv Shi4185 and Jimai22. Overexpressing GmTDN1 in wheat resulted in significantly improved drought and low‐N tolerance under drought and N‐deficient conditions in the greenhouse. Field trials conducted at three different locations over a period of 2–3 consecutive years showed that both Shi4185 and Jimai22 GmTDN1 transgenic lines were agronomically superior to wild‐type plants, and produced significantly higher yields under both drought and N‐deficient conditions. No yield penalties were observed in these transgenic lines under normal well irrigation conditions. Overexpressing GmTDN1 enhanced photosynthetic and osmotic adjustment capacity, antioxidant metabolism, and root mass of wheat plants, compared to those of wild‐type plants, by orchestrating the expression of a set of drought stress‐related genes as well as the nitrate transporter, NRT2.5. Furthermore, transgenic wheat with overexpressed NRT2.5 can improve drought tolerance and nitrogen (N) absorption, suggesting that improving N absorption in GmTDN1 transgenic wheat may contribute to drought tolerance. These findings may lead to the development of new methodologies with the capacity to simultaneously improve drought tolerance and N‐use efficacy in cereal crops to ensure sustainable agriculture and global food security.
Identification of a stripe rust resistance gene YrSF in Chinese wheat (Triticum aestivum) landrace Sifangmai
Authors: Feng Jing , Sun Jian Lu , Shah Syed Jawad Ahmad , Wang Fengtao , Yao Qiang , Guo Qingyun , Lin Ruiming , Xu Shichang 
Published: May 2022

AbstractWheat stripe rust is an important disease and can seriously threaten wheat production. The most economical, safe and effective approach to manage this disease is to breed and deploy resistant varieties. Sifangmai is a Chinese wheat landrace and maintained adequate resistance to the Chinese stripe rust races. In order to decipher genetic bases of resistance in Sifangmai, the F1, F2 and F2:3 of the cross Sifangmai/Taichung 29 were tested at adult stage with race CYR32. Genetic analysis revealed that resistance in Sifangmai was controlled by a single dominant gene named as YrSF. Six SSR on chromosome 5BS showed polymorphism among ‘Taichung 29’, Sifangmai, and resistant and susceptible bulks. Chinese Spring nulli‐tetrasomic and monosomic lines were confirmed YrSF on chromosome 5B. A linkage map of YrSF was constructed and the closely linked marker to YrSF was Xgpw8015 with 1.8 cM. Based on the comparisons of resistance infection type, pedigree analysis, gene origin and chromosomal position of previously reported Yr genes on chromosome 5B, YrSF is different from these known genes and is likely a novel gene.
Occupational COPD—The most under‐recognized occupational lung disease?
Authors: Murgia Nicola , Gambelunghe Angela 
Published: May 2022

AbstractChronic obstructive pulmonary disease (COPD) is caused by exposure to noxious particles and gases. Smoking is the main risk factor, but other factors are also associated with COPD. Occupational exposure to vapours, gases, dusts and fumes contributes to the development and progression of COPD, accounting for a population attributable fraction of 14%. Workplace pollutants, in particular inorganic dust, can initiate airway damage and inflammation, which are the hallmarks of COPD pathogenesis. Occupational COPD is still underdiagnosed, mainly due to the challenges of assessing the occupational component of the disease in clinical settings, especially if other risk factors are present. There is a need for specific education and training for clinicians, and research with a focus on evaluating the role of occupational exposure in causing COPD. Early diagnosis and identification of occupational causes is very important to prevent further decline in lung function and to reduce the health and socio‐economic burden of COPD. Establishing details of the occupational history by general practitioners or respiratory physicians could help to define the occupational burden of COPD for individual patients, providing the first useful interventions (smoking cessation, best therapeutic management, etc.). Once patients are diagnosed with occupational COPD, there is a wide international variation in access to specialist occupational medicine and public health services, along with limitations in workplace and income support. Therefore, a strong collaboration between primary care physicians, respiratory physicians and occupational medicine specialists is desirable to help manage COPD patients' health and social issues.