bluuebunny/crossref_metadata_2025_split huggingface dataset:
Percepción sobre uso de Fisiología en el Proceso Enfermero
Authors: Bianchi Maria Eugenia 
Published: September 2022

Introducción: el ejercicio de la enfermería requiere conocimiento integral del funcionamiento del cuerpo humano, por lo cual es imprescindible el aprendizaje de fisiología humana dentro del proceso formativo de grado. El proceso enfermero, herramienta para la práctica profesional sistemática, dinámica y oportuna basado en el método científico, constituye el eje organizador del currículo de la Licenciatura en Enfermería en la Universidad Nacional del Nordeste (Corrientes, Argentina). Objetivo: Identificar la percepción que estudiantes y docentes de asignaturas troncales de Enfermería tenían sobre la aplicación o no de conocimientos fisiológicos desarrollados en los trabajos prácticos de la asignatura Fisiología en las distintas etapas del proceso enfermero. Metodología: Se realizó un estudio descriptivo, observacional y transversal, cuestionario anónimo distribuido al azar a estudiantes y docentes, consistente en una tabla de doble entrada que describe los contenidos de cada trabajo práctico, por un lado, y las fases del proceso enfermero, por el otro. Resultados: respondieron 24 docentes (39 %) y 38 estudiantes (61 %). Las fases en que más reconocieron aplicar conocimientos de fisiología en el proceso enfermero fueron, en ambos grupos, valoración y diagnóstico; en cada trabajo práctico fue percibido diferente por docentes y estudiantes, siendo mayor el reconocimiento del uso de fisiología en el proceso enfermero por parte de docentes. Conclusiones: vertebrar la actividad práctica de fisiología alrededor del proceso enfermero parece constituir una estrategia didáctica válida, dado que docentes y estudiantes perciben, en mayor o menor medida, que aplican conocimientos trabajados en la asignatura en las distintas etapas del proceso enfermero, particularmente en la valoración y el diagnóstico. La percepción fue mayor en docentes, lo cual evidencia mejor manejo del proceso enfermero, por tener mayor nivel de conocimientos y práctica profesional.
Effect of Erector Spinae Block and PECS Block on Quality of Recovery and Analgesia After Modified Radical Mastectomy
Authors: Mohsin Md Hammad , . Hemlata , Verma Reetu , Singh Dinesh , Singh Sarita , Singh Kulranjan 
Published: September 2022

Objectives: Postoperative pain after modified radical mastectomy ranges from moderate to severe. Pectoralis block in comparison to Erector Spinae block have been found better in reducing pain scores and reducing consumption of rescue analgesic in postoperative period. This study aimed to compare the effect of Erector Spinae block and Pectoralis block on quality of recovery after Modified Radical Mastectomy using QoR-40 score. Methods: After general anaesthesia, patients were given block according to computer generated randomization. Group-I-Pectoralis block including PEC I AND PEC II(PECS), Group-II-Erector spinae block(ESP) and Group III-Control Group (No intervention). Quality of recovery (QoR-40) score was observed on morning of surgery and at 24 hrs. Time to rescue analgesia and total consumption of rescue analgesia in first 24 hrs. were also observed. Results: In the postoperative period at 24 hrs. Global QoR-40 scores were 183.64±6.36 in PECS group, 179.68± 6.38 in ESP group and 171.37±6.88 in control group. (p<0.0001) But, there was no statistically significant difference between QoR score of PECS & ESP group patients(p=0.0551). The total requirement of rescue analgesic was significantly lesser in PECS group (137.28±31.46 mg) in comparison to ESP Group(189.46±42.98mg) and control group (229.57±46.80 mg). (p<0.0001). Time to first rescue analgesia was significantly higher in PECS group (6.53±2.78 hrs) in comparison to ESP (4.05±2.91 hrs) and control group (2.15±1.51 hrs). (p<0.0001) Conclusion: Both Erector Spinae block and Pectoralis block are effective for improving QoR score and reducing consumption of rescue analgesic after modified radical mastectomy.
Keywords: breast surgery, cancer, postoperative recovery, postoperative pain
A Case Report of a Novel Atypical Mycobacterial Infection
Authors: McLaughlin C.M. , Schade M. , Cochran E. , Taylor K.F. 
Published: September 2022

Case:
A 76-year-old fisherman with a history of diabetes mellitus, coronary artery bypass grafting, and a previous ipsilateral elbow wound presented with a 1-year history of hand pain and swelling. Anti-inflammatories and antibiotics were administered without improvement. Magnetic resonance imaging and ultrasound demonstrated flexor tenosynovitis. Intraoperative cultures revealed Mycobacterium chimaera. The treatment course included 2 tenosynovectomies and a 1-year course of triple antimycobacterial therapy.

Conclusion:
Nontuberculous mycobacteria infections should be considered in cases of indolent tenosynovitis. M. chimaera should be considered in patients with a history of cardiopulmonary bypass given its association with cardiopulmonary heater-cooler units.
Interprosthetic Femur Fractures
Authors: McMellen Christopher J. , Romeo Nicholas M. 
Published: September 2022

» The prevalence of interprosthetic femur fractures (IFFs) is rising with the aging population and increased prevalence of total joint arthroplasty.» IFFs have high rates of complications and high associated morbidity and mortality.» The main treatment methods available for IFFs include plate fixation, intramedullary nailing, combined plate fixation and intramedullary nailing, and revision arthroplasty including partial and total femur replacement.» There have been several proposed classification systems and at least 1 proposed treatment algorithm for IFFs; however, there is no consensus.» Whichever treatment option is chosen, goals of surgery should include preservation of blood supply, restoration of length, alignment, rotation, and sufficient stabilization to allow for early mobilization.
Mobile Robot: Automatic Speech Recognition Application for Automation and STEM Education
Authors: Tran Duy Thanh , Truong Dang Huy , Le Hoanh Su , Huh Jun-Ho 
Published: September 2022

Abstract
Nowadays, Robots are widely applied in life as well as industrial production, medicine, rescue, learning and entertainment. There are many types of robots using different modern technologies that are divided into groups such as Robot Manipulator, Movement Robot, Biomimetic robot, each type is applied according to its own role. Robots are also applied in training, especially in STEM training. In this paper, we propose technical models to design Mobile Robot combined with Android OS Tablet with user interaction screen, voice control model and AIDL IPC interactive model for remote control. Mobile Robot's motion as well as giving a layered UML Model for motion handling towards open source. We research the Mobile Robot using RockChip AI Processor RK3399Pro, which focuses on understanding the structure and operating mechanism of the AI Processor that RockChip Robot uses, along with researching Android with IPC AIDL architecture and with Automatic Voice Recognition technology to control Robot to turn left, turn right, move forward, backward, jump or stop motion by voice with three languages: Korean, English and Vietnamese. From there, it will serve as a foundation for the research and development of a system to support students in learning by interacting with robots through voice in the form of gamification of the curriculum, especially for extensive research on training programs, created in the STEM field.
Differential expression of m5C RNA methyltransferase genes NSUN6 and NSUN7 in Alzheimer’s disease and Traumatic Brain Injury
Authors: Grovas-Saltijeral Adriana Perez , Rajkumar Anto P. , Knight Helen Miranda 
Published: September 2022

Abstract
Epigenetic processes have become increasingly relevant in understanding disease modifying mechanisms. 5-methylcytosine methylation of DNA (5mC) and RNA (m5C) have functional transcriptional and RNA translational consequences and are tightly regulated by writers, readers, and erasers effector proteins. To investigate the involvement of 5mC/5hmC and m5C effector proteins contributing to the development of dementia neuropathology, RNA-sequencing data for 32 effector proteins across four brain regions was examined in 51 aged non-affected and 56 Alzheimer’s disease (AD) individuals obtained from the Aging, Dementia and Traumatic Brain Injury (TBI) study. Gene expression profiles were compared between AD and controls, neuropathological Braak and CERAD scores and in individuals with a history of TBI. We found an increase in DNA methylation writers DNMT1, DNMT3A, DNMT3B mRNA and decrease in reader UHRF1 mRNA in AD samples across three brain regions while the DNA erasers GADD45B and AICDA showed changes in mRNA abundance within neuropathological load groupings. RNA methylation writers NSUN6 and NSUN7 showed significant expression differences with AD and, along with the reader, ALYREF, differences in expression for neuropathologic ranking. A history of TBI was associated with a significant increase in the DNA readers ZBTB4 and MeCP2 (p < 0.05) and decrease in NSUN6 (p < 0.001) mRNA. These findings implicate regulation of protein pathways disrupted in AD and TBI via multiple pre- and post-transcriptional mechanisms including potentially acting upon tRNAs, enhancer RNAs, as well as nuclear-cytoplasmic shuttling and cytoplasmic translational control. The targeting of such processes provides new therapeutic avenues for neurodegenerative brain conditions.
Effect of an Artificial Intelligence-assisted Antibiotic Susceptibility Test on Reducing the Mortality Rate of and Antibiotics Use in Patients with Bacteremia: A Prospective Observational Cohort Study
Authors: Wang Hsin-Yao , Chung Chia-Ru , Tseng Yi-Ju , Huang Yhu-Chering , Yu Jia-Ruei , Chen Chao-Jung , Lin Ting-Wei , Huang Wan-Ting , Lee Tzong-Yi , Horng JT , Lu Jang-Jih 
Published: September 2022

Abstract
No mass spectrometry-based antibiotic susceptibility test (AST) AI system has been robustly validated and truly deployed in real-world settings. In the study, an AI-assisted AST prediction system XBugHunter was extensively validated and deployed. A total of 90,064 consecutive patients were included in the models development. During the deployment, 155 consecutive patients with Staphylococcus aureus bacteremia (SAB) was analyzed, whereas the historical control cohort included 455 patients. The predictive sensitivity and specificity for S. aureus (oxacillin) were 0.95 and 0.97, respectively. The reduction on AST turnaround time was 34.06 h. Death within 28 days was 13.55% for the SAB patients in the XBugHunter intervention group, which was significantly lower than 17.58% in the historical control cohort. Totally, 114.77 defined daily doses of inappropriate antibiotics were avoided by deploying XBugHunter. This work showed that XBugHunter can prevent inappropriate antibiotic use, and the adjustment in antibiotic treatment can yield a lower mortality rate.
From Collaborative Care to Population-based Management for Depression in Primary Care: Development of Clinical Databases and Applications for Quality Improvement and Research
Authors: Savitz Samuel Thomas , Kurtzhals Aaron , Drews Maureen , Breitinger Scott A. , Sawchuk Craig N , Leasure William , Brennan RoxAnne M , Lebow Jocelyn , Angstsman Kurt B , Williams Mark D. 
Published: September 2022

Abstract
Background: To describe the process of developing an evolving database for Mayo Clinic primary care patients who screen positive for depression. The databases will support a broad use of these data for current and future quality improvement and research efforts. The description of their development will serve as an example for other institutions attempting to create similar data resources.
Methods: The adult database (patients aged ³ 18) has data from 2007 and the adolescent database (patients aged 12 to < 18) from 2011. To be included, a patient had to be eligible for collaborative care model as a primary care patient with at least moderate symptoms of unipolar depression. The patient did not have to be enrolled in collaborative care model. The main domains of measurement are demographics, social determinants of health, mental health and substance abuse conditions, other comorbidities, interaction with collaborative care model, and questionnaire results. The data is being continuously updated as new data becomes available.
Results: The adult database currently includes 117,619 unique patients with a mean age of 44.7 years, and is 66.4% female, and 88.1% non-Hispanic white. The adolescent database includes 14,684 unique patients with a mean age of 14.8 years, is 66.7% female, and 79.7% non-Hispanic white.
Conclusions: These large, longitudinal, and evolving databases are a key step towards developing a learning environment to improve quality of care and conduct population-based research for patients with depression in primary care settings.
The Effect of Organizational Culture on Organizational Commitment During Covid-19: Evidence From Debre Markos Referral Hospital
Authors: Asresie Gessesse Gizachew , Birara Mulugeta Belayneh , Gebrie Tadesse Asmare 
Published: September 2022

Abstract
During the covid-19 pandemic, a number of workers refused to provide services and attendance at their workplaces, and forgot about their organizational commitments. Today the industry setup is shifting in relation to the worldwide epidemic of Covid-19. The purpose of this study was to investigate the effect of organizational culture on employee commitment during covid-19 in debre Markos referral hospital. The study employed explanatory research design and qualitative research approach. To achieve the objectives of the study, 244 sample respondents were taken by using simple random sampling techniques from total populations of 627 employees. The data was gathered through a five point lickert scale standardized questionnaire from target respondents. After gathering the required data the study employed descriptive and inferential statistical data analysis methods for instance, mean and standard deviations, correlation, and multiple regressions. The regression analysis has been used to determine the effect of supportive organizational culture, innovative organizational culture and bureaucratic organizational culture on organizational commitment during covid-19. The findings of the study reveal that innovative and supportive organizational culture factors have a positive significant effect on organizational commitment. On contrary, bureaucratic organizational culture traits, has not significant effect on organizational commitment in the study area.
Correlates of host-associated bacterial diversity in New Zealand cicadas and hybrids
Authors: Haji Diler , Vailionis Jason , Stukel Mark , Gordon Eric , Lemmon Emily Moriarty , Lemmon Alan R. , Simon Chris 
Published: September 2022

AbstractHost-microbe interactions are intimately linked to eukaryotic evolution, particularly in sap-sucking insects that often rely on obligate microbial symbionts for nutrient provisioning. Cicadas (Cicadidae: Auchenorrhyncha) specialize on xylem fluid and derive many essential amino acids and vitamins from intracellular bacteria or fungi (Hodgkinia,Sulcia, andOphiocordyceps) that are propagated via transmission from mothers to offspring. Despite the beneficial role of these symbionts in nutrient provisioning, they are generally not considered to function within the gut where microbiota may play dietary roles. Here, we investigate the relative abundance and impact of host phylogeny and ecology on gut microbial diversity in cicadas using 16S ribosomal RNA gene amplicon sequencing data from 197 wild-collected cicadas and new mitochondrial genomes across 38 New Zealand cicada species, including natural hybrids between one species pair. We find low abundance and a lack of phylogenetic structure and hybrid effects but a significant role of elevation in explaining variation in gut microbiota.
Genomic attributes of Vibrio cholerae responsible for a massive cholera outbreak in Bangladesh, 2022
Authors: Alam Munirul , Monir Md Mamun , Islam Mohammad Tarequl , Mazumder Razib , Mondal Dinesh , Nahar Kazi Sumaita , Sultana Marzia , Morita Masatomo , Ohnishi Makoto , Huq Anwar , Watanabe Haruo , Qadri Firdausi , Rahman Mustafizur , Thomson Nick , Seed Kimberley , Colwell Rita R. , Ahmed Tahmeed 
Published: September 2022

Abstract
Bangladesh is currently experiencing one of the worst cholera outbreaks in its history. The icddr,b hospital has treated a record number of patients, more than 1400 per day and ca. 40,000 diarrheal cases from the end of March through April 20221. A recent genomic study showed temporal progression of two lineages, BD-1 and BD-2, with the former linked to the 7th pandemic wave-3 global clade and the latter predominant in endemic cholera in Dhaka during 2013 and 20172. Here, we present genomic attributes of V. cholerae O1 responsible for the 2022 Dhaka cholera epidemic and genome phylogeny of 960 7th pandemic El Tor strains from 88 countries. Results show the Dhaka cholera etiological agent clustered with the 7th pandemic El Tor wave-3 global clade, but comprises a new subclade, BD-1.2, for which the most recent common ancestor appears to be of the globally distributed sublineage predominantly associated with recent endemic cholera in India. Results also suggest BD-1.2 was present in Bangladesh since 2016. However, it was not until 2018 that strains of the subclade successfully established dominance over the BD-2 during an expansion of the wave-3 global clade. It is concluded that the recent shift in predominant lineage and the observed genetic changes including serotype switch in BD-1.2 from Ogawa to Inaba may explain the increasing number of infections and massive outbreak of cholera during 2022 in Bangladesh.
The Proteomics and Metabolomics Studies of GZU001 on Promoting the Merisis of Maize (Zea mays L.) Roots
Authors: Zheng Zhiguo , Chen Shunhong , Wei Panpan , Guo Shengxin , Yu Gang , Wu Jian 
Published: September 2022

Abstract
Background
Plant growth regulators are chemicals that regulate plant growth and development, which can regulate hormonal balance and affect plant growth, thereby increasing crop yield and/or improving crop quality. We discovered a novel compound (GZU001), a potential plant growth regulator, that significantly promoted root elongation in maize. However, an underlying potential mechanism is still under study.
Results
To explore the response pathway and regulation mechanism of GZU001 in promoting maize root elongation, the current study used a combination of metabolomics and proteomics study. From the appearance, we can see that both roots and plants of maize treated with GZU001 are significantly improved. In the metabolic process of maize roots, glucose not only acts as a nutrient molecule, but also plays a dual role as a signal molecule, which plays an important role in promoting plant growth and development. In total, 101 differentially abundant proteins (DAPs) and 79 differentially expressed metabolites were identified. The current study identified altered proteins and metabolites associated with physiological and biochemical processes. These processes are mainly involved in carbohydrate metabolism, amino acid metabolism, energy metabolism and secondary metabolism, indicating that the enhancement of primary metabolism after GZU001 treatment is beneficial to the growth and development of maize, and plays an important role in maintaining metabolism and growth and development.
Conclusions
This study recorded the changes of related proteins and metabolites in maize roots after GZU001 treatment, and provided evidence for the action mode and mechanism of this compound in plants.
Negative appendectomy rate in patients diagnosed with acute appendicitis
Authors: Chaochankit Wongsakorn , Boocha Aeraungkoon , Samphao Srila 
Published: September 2022

Abstract
Background: Acute appendicitis is the most common cause of acute lower abdominal pain leading patients to the emergency department. This study aims to find the negative appendectomy rate in patients diagnosed with acute appendicitis from 2015-2019.
Methods: This study was a retrospective cohort study in the patients preoperatively diagnosed with acute appendicitis and underwent appendectomy from January 2015 to December 2019. Negative appendectomy is defined as the final pathologic results confirmed normal, congestion or peri-appendicitis.
Results: The study population was 892 patients which was 54.3% female. The five-year negative appendectomy rate was 8.6% (n=77) and 70% in female (n=54). The factors associated with increasing the negative appendectomy rate were female (OR 2.23, P=0.003), age £ 40 years old (OR 2.35, P=0.003), and no history of diarrhea (OR 2.42, P=0.017). Whereas the factors related to decline in the negative appendectomy rate were white blood cell count (WBC) ≥10,000 (OR 0.39, P=0.016), neutrophil (N) ≥75% (OR 0.28, P< 0.001), and positive appendicitis from ultrasonography of abdomen (OR 0.04, P<0.001) or computed tomography of abdomen (OR 0.07, P< 0.001).
Conclusion: The negative appendectomy rate was less than 10% in this study. Female, age 40 £ years old and history of diarrhea were related to increase in negative appendectomy. The factors that related to decline in negative appendectomy were leukocytosis with cells shift to the left, positive acute appendicitis from abdominal ultrasonography and CT scan. However, to request the further imaging studies to diagnose patients with suspected acute appendicitis depends on the risk and benefit to each patient and the choice of investigation.
Horro and their crossbred dairy cow’s reproductive performance in Ethiopia subhumid tropical environments
Authors: Jalata Beshatu , Goshu Habtamu Abera , Mediksa Tesfaye , Bekele Dereje , Aliye Mohammed 
Published: September 2022

AbstractThe estrus detection system, proper time of insemination, feeding, and health care practices each make a significant contribution towards the herd's optimal breeding efficiency and lifetime production. In the subhumid environments of Ethiopia, the age at first calving, days open, calving to first heat, and services per conception are economic traits in the reproductive performance of Horro and theircrossbreddairy cows. As a result, data collected at Ethiopia's Bako Agricultural Research Center from 1980 to 2019 were used to study the reproductive performance of Horro and their crosses with Holstein Friesian and Jersey dairy cows. The overall mean ± standard error of age at first service (AFS), age at first calving (AFC), number of services per conception (NSP), calving interval (CI), days open (DO), conception rate (CR), and replacement rate (RR) were 29.2±0.2 months, 39.8±0.2months,1.76±0.4, 13.2±0.3 months, 94.3±4.3 days, 75.0±1.3%, and 28.4±0.3%, respectively.At 60 and 90 days, the odds ratio of the nonreturn rate (NRR) was 0.22 and 0.96, respectively.The breeds (sire and dam) and birth period had a significant (P< 0.001) influence on AFS and AFC, whereas season and dam parity had a significant influence on CI and DO.Inconsistent management in feeding, heat detection, inseminator skills, insemination time, health, and other husbandry practices may result in extended periods of AFS, AFC, CI, and DO. To improve the reproductive performance of Horro and their crosses with Holstein Friesian and Jersey dairy cows in Ethiopia's subhumid environments, we should focus on increasing management factors.