bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimal effectiveness of heart failure management — an umbrella review of meta-analyses examining the effectiveness of interventions to reduce (re)hospitalizations in heart failure
Authors: Hafkamp Frederique J. , Tio Rene A. , Otterspoor Luuk C. , de Greef Tineke , van Steenbergen Gijs J. , van de Ven Arjen R. T. , Smits Geert , Post Hans , van Veghel Dennis 
Published: March 2022

AbstractHeart failure (HF) is a major health concern, which accounts for 1–2% of all hospital admissions. Nevertheless, there remains a knowledge gap concerning which interventions contribute to effective prevention of HF (re)hospitalization. Therefore, this umbrella review aims to systematically review meta-analyses that examined the effectiveness of interventions in reducing HF-related (re)hospitalization in HFrEF patients. An electronic literature search was performed in PubMed, Web of Science, PsycInfo, Cochrane Reviews, CINAHL, and Medline to identify eligible studies published in the English language in the past 10 years. Primarily, to synthesize the meta-analyzed data, a best-evidence synthesis was used in which meta-analyses were classified based on level of validity. Secondarily, all unique RCTS were extracted from the meta-analyses and examined. A total of 44 meta-analyses were included which encompassed 186 unique RCTs. Strong or moderate evidence suggested that catheter ablation, cardiac resynchronization therapy, cardiac rehabilitation, telemonitoring, and RAAS inhibitors could reduce (re)hospitalization. Additionally, limited evidence suggested that multidisciplinary clinic or self-management promotion programs, beta-blockers, statins, and mitral valve therapy could reduce HF hospitalization. No, or conflicting evidence was found for the effects of cell therapy or anticoagulation. This umbrella review highlights different levels of evidence regarding the effectiveness of several interventions in reducing HF-related (re)hospitalization in HFrEF patients. It could guide future guideline development in optimizing care pathways for heart failure patients.
Utilization of synthetic nano-cryptomelane for enhanced scavenging of cesium and cobalt ions from single and binary solutions
Authors: Ghaly M. , Metwally S. S. , El-Sherief E. A. , Saad E. A. , Abdel Rahman R. O. 
Published: March 2022

AbstractThe feasibility of using nano-cryptomelane for elimination of cobalt and cesium metal ions from their single and binary solutions was studied. In this respect, the material was prepared and characterized to confirm its chemical composition and structure. Results illustrate that the synthesized nano-cryptomelane has a tunnel structure with particle size ranged between 4 and 6 nm. The material feasibility was detected by conducting a series of batch experiments for determination of the kinetic and equilibrium performance of the removal process. All characteristic Raman bands for Mn–O lattice vibrations within the (2 × 2) tunnel structure of MnO6 octahedral are observed which confirm formation of nano-cryptomelane. The specific surface area (SSA) for nano-cryptomelane was calculated and equal to 299.03 m2/g while the surface fractal information (Ds) was2.53. The process sensitivity to changes of H+ concentration is attributed to changes in structural elements-species distribution at the solid/aqueous interface. The pH optimum value was desired at pH 5 for exchange of Cs+ and/or Co2+ with K+ ions. The equilibrium studies show that Langmuir isotherm model was more fitted to the experimental data than that of Freundlich model.
A construction of left equalizer simple medial semigroups
Authors: Nagy Attila 
Published: March 2022

AbstractA semigroup S is said to be left equalizer simple if, for all elements a, b, x, y of S, $$xa=xb$$

x
a
=
x
b

implies $$ya=yb$$

y
a
=
y
b

. It is known that left equalizer simplicity is a necessary condition for a semigroup to be embedded in a left simple semigroup. A semigroup satisfying the identity $$axyb=ayxb$$

a
x
y
b
=
a
y
x
b

is called a medial semigroup. In this paper we show how to construct left equalizer simple medial semigroups, especially, medial semigroups which can be embedded in idempotent-free left simple semigroups.
A percentile rank score of group productivity: an evaluation of publication productivity for researchers from various fields
Authors: Yamamoto Koh , Yasunaga Takuo 
Published: March 2022

AbstractThe difficulty in evaluating the research performance of groups is attributable to the following two factors: 1) difference of population size or discipline of group members and 2) skewed distribution of the research performance of individuals. This study attempts to overcome this difficulty, focusing on the research performance based on publication productivity. We employ the normalized index for the number of papers, in which publication efficiency was considered and disciplinary variation in the publication intensity was corrected by the disciplinary averages, to calculate a new percentile rank score. The score was developed on the basis of the principle that a person who is rare is valuable. The score was also tested with publication data for faculty members of 17 Japanese universities. The employment of the normalized index increased the score of universities with relatively few faculty members working in the disciplines of high productivity, resulting in more plausible university rankings. The rankings show a high correlation with those for a previously established percentile rank score, which was developed for citation analysis, and they are consistent with the judgment by evaluators of several universities under study. The advantage of the new score over the previous one is that it has no room for arbitrariness in determining the scheme of rank classification and the weights given to each rank class.
Metacognitive judgements and abilities in patients with affective disorders
Authors: Drueke Barbara , Gauggel Siegfried , Weise Lorenz , Forkmann Thomas , Mainz Verena 
Published: March 2022

Abstract
Objectives
Cognitive and metacognitive deficits depict important factors in depression, but the relationship between these concepts remains to be elucidated. The present study investigated the difference between patients with depression and controls in metacognitive judgements regarding the domain of attention. Furthermore, the associations between different metacognitive abilities, depressiveness and confidence were investigated, as well as in how far the derived correlates would predict depression.

Methods
Thirty patients with a major depressive episode and 30 healthy participants were enrolled in the current study. Attention and executive functioning ability were assessed including metacognitive judgements of performance and confidence with regard to the test performance in the Stroop test. To examine further aspects related to (meta-)cognitive abilities, decentering skills, aspects of self-conscious attention, self-assessed intelligence and metacognitive beliefs, judgements and monitoring tendencies were assessed.

Results
Albeit groups’ metacognitive judgements of performance did not differ, patients indicated to be significantly less confident in their judgements. Depressive patients showed less decentering abilities compared to healthy participants and there was a significant association between decentering and confidence ratings. Moreover, depressiveness was associated with dysfunctional self-consciousness and low cognitive confidence. Finally, lower decentering skills and higher dysfunctional self-attention were the best predictors for depressiveness.

Conclusions
Results favor the assumption that patients’ metacognitive abilities regarding the domain of attention are not generally deficient. Rather, the lower confidence in their judgements and dysfunctional (meta-)cognitive abilities, like decentering, metacognitive beliefs and aspects of self-conscious attention and intelligence, seem to mirror the patients’ impairments.
Economic benefits of immigration for natives: the effects of immigrants through the school system
Authors: Jinno Masatoshi , Yasuoka Masaya 
Published: March 2022

AbstractImmigration can have indirect negative effects, such as the additional burden of providing education to immigrant children who may need more support than native children to master the culture, customs, and language of the host country. This also leads to a transition of labor from the consumption sector to the education sector and a change in the number of children through the costs of education. Thus, using an overlapping generation model, we examine the effects of immigration on the welfare of the native population with the burden of providing schooling to native and immigrant children with endogenous fertility rates and endogenous unemployment rates. The results indicate that immigration may improve the welfare of the native population when the number of educators required for immigrant children is sufficiently low. Moreover, whether immigration improves the welfare of the native population depends not on the productivity of immigrants but on the increment in the number of educators caused by immigration.
Effects of Formic Acid Preservation of Fishbones on the Extractability of Ammonium Lactate–Acetate Soluble Calcium, Phosphorus, Magnesium, and Potassium
Authors: Løes Anne-Kristin , Ahlin Johan Petter , Ahuja Ishita , Krogstad Tore , Smevoll Ståle , Waag Hanne 
Published: March 2022

AbstractFishbones contain significant amounts of plant nutrients. Fish residues may be preserved by acidification to pH < 4, which may affect the chemical extractability, and the plant availability of nutrients when applied as fertilisers. Grinded bone material from cod (Gadus morhua) heads was mixed with formic acid to investigate if this would increase the concentrations of ammonium lactate–acetate (AL)-extractable nutrients. Two degrees of fineness of fishbones (coarse 2–4 mm; fine < 0.71 mm) were compared at pH 3.0 and 4.0 plus a water control in a laboratory study over 55 days. Samples for measurement of AL-extractable P, Ca, Mg and K were taken on day 2, 15, 34 and 55. Whereas more formic acid and thereby lower pH clearly increased the concentrations of AL-extractable calcium (Ca-AL) and magnesium (Mg-AL), AL-extractable phosphorus (P-AL) was only significantly increased in finely grinded bones at pH 3. After 34 days at pH 3, 6% of the total content of P was extracted by AL in fine fishbones. In the water control, about 1% of the P was extracted, possibly from phospholipids. This P-AL concentration was well above P-AL extracted from acidified coarse fishbones (pH 3 and 4) and from fine fishbones acidified to pH 4. With acidification, about 30% of total Ca and 100% of total Mg were extracted by AL, and the Ca-AL and Mg-AL concentrations were closely correlated. A possible reason for lower P-AL in coarse fishbones at pH 3 and 4, and in fine fishbones at pH 4 than in water controls may be a precipitation of apatite from phospholipids and dissolved calcium.
Graphical Abstract
Antifibrogenic and apoptotic effects of Ocoxin in cultured rat hepatic stellate cells
Authors: Ruiz de Galarreta Marina , Arriazu Elena , Pérez de Obanos María P. , Ansorena Eduardo , Iraburu María J. 
Published: March 2022

Abstract
Ocoxin is a nutritional supplement that has been shown to exert antioxidant and immunomodulatory responses in patients with chronic hepatitis C. The present work aimed to determine the effects of Ocoxin on activated hepatic stellate cells (HSC), the cell type mainly responsible for collagen deposition in the fibrotic liver. Ocoxin was found to reduce the survival of a cell line of immortalized non-tumoral rat HSC in a dose–response fashion and to diminish collagen type I levels. This latter effect was observed even at doses not affecting cell survival, pointing to an antifibrogenic action for the supplement. The decrease in viability exerted by Ocoxin on HSC correlated with an increase in histone-associated fragments in the cytoplasm and with increased activity of caspase-3, indicating the induction of apoptosis. To determine the molecular mechanisms mediating Ocoxin-induced apoptosis, the activation of members of the MAPK family was analyzed. Incubation of HSC with Ocoxin caused a transient and dramatic enhancement on ERK, JNK, and p38 MAPK phosphorylation levels. Using specific inhibitors for these enzymes, p38 MAPK was identified as a key mediator of the apoptotic effect of Ocoxin on HSC.
Feasibility and usability of a regional hub model for colorectal cancer services during the COVID-19 pandemic
Authors: Carvalho Filipe , Rogers Ailín C. , Chang Tou-Pin , Chee Yinshan , Subramaniam Dhivya , Pellino Gianluca , Hardy Katy , Kontovounisios Christos , Tekkis Paris , Rasheed Shahnawaz ,   London Colorectal Cancer Hub Network Collaborators, Karim A , Chung A , Ramwell A , Hagger R , West N , Toquero L , Gupta A , Toomey P , Raja A , Pawa N , Mills S , Warren O , Nicolay C , Thava B , Daulatzai N , Jenkins I , Miskovic D , Burns E , Antoniou A , Agarwal T , Sinha N , Slesser A , Prabhudesai A , MohsenMyers Y A , Harris S , Mohamed S , Abulafi M , Shanmuganandan A , Dellen J 
Published: March 2022

AbstractThe outbreak of the COVID-19 pandemic produced unprecedented challenges, at a global level, in the provision of cancer care. With the ongoing need in the delivery of life-saving cancer treatment, the surgical management of patients with colorectal cancer required prompt significant transformation. The aim of this retrospective study is to report the outcome of a bespoke regional Cancer Hub model in the delivery of elective and essential colorectal cancer surgery, at the height of the first wave of the COVID-19 pandemic. 168 patients underwent colorectal cancer surgery from April 1st to June 30th of 2020. Approximately 75% of patients operated upon underwent colonic resection, of which 47% were left-sided, 34% right-sided and 12% beyond total mesorectal excision surgeries. Around 79% of all resectional surgeries were performed via laparotomy, and the remainder 21%, robotically or laparoscopically. Thirty-day complication rate, for Clavien–Dindo IIIA and above, was 4.2%, and 30-day mortality rate was 0.6%. Re-admission rate, within 30 days post-discharge, was 1.8%, however, no patient developed COVID-19 specific complications post-operatively and up to 28 days post-discharge. The established Cancer Hub offered elective surgical care for patients with colorectal cancer in a centralised, timely and efficient manner, with acceptable post-operative outcomes and no increased risk of contracting COVID-19 during their inpatient stay. We offer a practical model of care that can be used when elective surgery “hubs” for streamlined delivery of elective care needs to be established in an expeditious fashion, either due to the COVID-19 pandemic or any other future pandemics.
Societal Inputs, Religious Outputs, and Young Adults: A Cross-Cohort Analysis of Attitudes toward Same-Sex Relations and Civil Liberties for Gays and Lesbians
Authors: Barringer M. N. , Savage B. 
Published: March 2022

Background Within an open systems theorization, the degree to which religious identity and attendance at religious services influence attitudes toward same-sex relations and civil liberties for gays and lesbians will be shaped by how religious groups respond to societal inputs over time. In recent decades, while some Christian denominations in the United States have remained resolute in their condemnatory stance on these issues, the religious outputs of others have become more tolerant. A cross-cohort examination of the influence of religious identity and attendance at religious services on such attitudes can help uncover effects of this interplay over time. Purpose The present study tests the significance of religious identity and attendance at religious services on attitudes toward same-sex relations and civil liberties for gays and lesbians, comparing young adults across the Baby Boomer, Generation X, and Millennial cohorts. The uniqueness of the study is twofold: (1) Cross-cohort analyses are used to compare young adults within a single study rather than examining each cohort in isolation, and (2) the analyses are contextualized within an open systems framework. Methods Data from the General Social Survey are used to examine the significance of religious identity and attendance at religious services on the attitudes of young adults (ages 20–37) toward moral acceptance of same-sex relations and civil liberties of gays and lesbians. Multiple linear regression analyses are used to test for significant differences across three birth cohorts, controlling for relevant sociodemographics. Results The analyses demonstrate cross-cohort change in the significance of religious identity on attitudes about the morality of same-sex relations and the civil liberties of gays and lesbians, while attendance at services is consistently a strong predictor across the generations. Of particular interest, among Millennial young adults, unlike previous generations, the evangelical Protestant identity does not affect attitudes about civil liberties for gays and lesbians. Conclusions and Implications The findings suggest the importance of examining the interplay of religious outputs and societal inputs and how these dynamics influence public opinion over time. This study reveals a need for increased research into how societal inputs have shifted the output of religious organizations, not just toward gays and lesbians, but also other sexual and gender minorities.
Physical activity, Sedentary Behaviour and Their Correlates in Adults with Autism Spectrum Disorder: a Systematic Review
Authors: Thompson C. , Brook M. , Hick S , Miotti C. , Toong R. , McVeigh JA. 
Published: March 2022

Abstract
The aim of this systematic review was to investigate what is currently known about autistic adults’ participation in physical activity and sedentary behaviour and explore any associated correlates of these behaviours. The databases EMBASE, MEDLINE, PsycINFO, PubMed, and SPORTDiscus were searched for relevant literature. The review was registered with PROSPERO (No. 189187). The search identified 2834 papers, with 12 meeting the criteria for inclusion. Correlates of physical activity and/or sedentary behaviour were reported in eight included studies. The limited evidence identified suggest that autistic adults are unlikely to meet Australia’s physical activity guidelines. Future research should use device-derived measurement to more accurately quantify activity levels within the autistic adult population.
Digitalization and Banking Crisis: A Nonlinear Relationship?
Authors: Ben Ali Mohamed Sami 
Published: March 2022

AbstractThis study assesses the impact that ICT can have on the occurrence of banking crisis for a sample of 113 countries over the period 1996–2017 while considering the interfering role of corruption and the potential existence of a nonlinear relationship for the ICT-banking crisis nexus. We consider countries with varying income levels to check for the stability of the relationship. Our estimation results show that more highly ICT endowed countries can improve the resilience of the banking system. The study provides evidence that ICTs do not produce the same effect regardless of a country’s level of income. Estimation outcomes show the existence of a threshold effect driving the ICT-banking stability nexus. More results show that Information and communication technologies can improve the stability of the banking system only when corruption is relatively low. However, when corruption is endemic, ICT endowment is useless for the stability of the banking system.
RNA-seq analysis of gene expression profiles in posttraumatic stress disorder, Parkinson’s disease and schizophrenia identifies roles for common and distinct biological pathways
Authors: Hemmings Sian M. J. , Swart Patricia , Womersely Jacqueline S. , Ovenden Ellen S. , van den Heuvel Leigh L. , McGregor Nathaniel W. , Meier Stuart , Bardien Soraya , Abrahams Shameemah , Tromp Gerard , Emsley Robin , Carr Jonathan , Seedat Soraya 
Published: March 2022

AbstractEvidence suggests that shared pathophysiological mechanisms in neuropsychiatric disorders (NPDs) may contribute to risk and resilience. We used single-gene and network-level transcriptomic approaches to investigate shared and disorder-specific processes underlying posttraumatic stress disorder (PTSD), Parkinson’s disease (PD) and schizophrenia in a South African sample. RNA-seq was performed on blood obtained from cases and controls from each cohort. Gene expression and weighted gene correlation network analyses (WGCNA) were performed usingDESeq2andCEMiTool,respectively. Significant differences in gene expression were limited to the PTSD cohort. However, WGCNA implicated, amongst others, ribosomal expression, inflammation and ubiquitination as key players in the NPDs under investigation. Differential expression in ribosomal-related pathways was observed in the PTSD and PD cohorts, and focal adhesion and extracellular matrix pathways were implicated in PD and schizophrenia. We propose that, despite different phenotypic presentations, core transdiagnostic mechanisms may play important roles in the molecular aetiology of NPDs.
Demands of Justice
Authors: Clark Ann Marie 
Published: March 2022

Demands of Justice draws on original interviews and archival research to show how global appeals for human rights began in the 1970s to expand the boundaries of the global neighbourhood and disseminate new arguments about humane concern and law in direct opposition to human rights violations. Turning a justice lens on human rights practice, Clark argues that human rights practice offers tools that enrich three facets of global justice: transnational expressions of simple concern, the political realization of justice through politics and law, and new but still incomplete approaches to social justice. A key case study explores the origins of Amnesty International's well-known Urgent Action alerts for individuals, as well as temporal change in the use of law in such appeals. A second case study, of Oxfam's adoption of rights language, demonstrates the spread of human rights as a primary way of expressing calls for justice in the world.
ON INTEGER SETS WITH THE SAME REPRESENTATION FUNCTIONS
Authors: JIAO KAI-JIE , SÁNDOR CSABA , YANG QUAN-HUI , ZHOU JUN-YU 
Published: March 2022

AbstractLet
$\mathbb {N}$
be the set of all nonnegative integers. For
$S\subseteq \mathbb {N}$
and
$n\in \mathbb {N}$
, let
$R_S(n)$
denote the number of solutions of the equation
$n=s_1+s_2$
,
$s_1,s_2\in S$
and
$s_1<s_2$
. Let A be the set of all nonnegative integers which contain an even number of digits
$1$
in their binary representations and
$B=\mathbb {N}\setminus A$
. Put
$A_l=A\cap [0,2^l-1]$
and
$B_l=B\cap [0,2^l-1]$
. We prove that if
$C \cup D=[0, m]\setminus \{r\}$
with
$0<r<m$
,
$C \cap D=\emptyset $
and
$0 \in C$
, then
$R_{C}(n)=R_{D}(n)$
for any nonnegative integer n if and only if there exists an integer
$l \geq 1$
such that
$m=2^{l}$
,
$r=2^{l-1}$
,
$C=A_{l-1} \cup (2^{l-1}+1+B_{l-1})$
and
$D=B_{l-1} \cup (2^{l-1}+1+A_{l-1})$
. Kiss and Sándor [‘Partitions of the set of nonnegative integers with the same representation functions’, Discrete Math.340 (2017), 1154–1161] proved an analogous result when
$C\cup D=[0,m]$
,
$0\in C$
and
$C\cap D=\{r\}$
.