bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diverse Synthetic Approaches and Biological Activities of Lucrative Pyrimidine-
Triazine Hybrid Derivatives: A Review
Authors: Asgaonkar Kalyani , Patil Shital , Pradhan Kunal , Tanksali Sushruti , Jain Jidnyasa 
Published: September 2022

Abstract:
Pyrimidine and Triazine are rewarding pharmacophores as seen from their presence in
different naturally and synthetically occurring drug molecules. Hybridization is a functional concept used in drug design. This updated review encompasses various synthetic procedures that
have been used to prepare molecular hybrids of Pyrimidine and Triazine, detailed structureactivity relationship, and molecular docking studies with patents granted. The most potent and
promising hybrid compounds have also been identified. The study has revealed the synthetic feasibility of Pyrimidine- Triazine hybrids along with a plethora of potent biological activities such
as Anticonvulsant, Antiviral, Anti-inflammatory, Analgesics, etc. This paper highlights the importance of coupling Pyrimidine and Triazine to provide better insight for medicinal chemists to
further explore the hybrid for a significant therapeutic effect.
de Quervain’s Tenosynovitis with Accessory Abductor Pollicis Longus
Tendon and ‘Wartenberg’s syndrome’ - A Case Report
Authors: Siddiq Md Abu Bakar 
Published: September 2022

Background:
de Quervain's tenosynovitis (dQT) is focal soft-tissue rheumatism of ab-ductor pollicis longus (APL) and extensor pollicis brevis (EPB) tendons. The Swiss surgeon Fritz de Quervain first demonstrated the disorder in 1895. Anatomical variation of the first wrist extensor compartment, for example, accessory APL, can be associated with de Quervain's tenosynovitis. Sometimes, dQT may coexist with superficial radial nerve (SRN) compression, widely known as 'Wartenberg’s syndrome'.

Case Presentation:
In the present case study, clinical features of de Quervain's tenosynovitis have been described in a 45-year-old housewife without any known risk factor for the disorder. The pa-tient complained of pain and swelling on the radial aspect of dorsal wrist; there was local tender-ness, and the Finkelstein test was positive. An ultrasonogram of the wrist's first extensor compart-ment depicted a thick, hypoechoic tenosynovial sheath encircling two APL and one EPB tendon. Swollen first extensor wrist compartment compressing the SRN led to tingling and dysesthesia, 'Wartenberg’s syndrome.'

Conclusion:
de Quervain's tenosynovitis with accessory abductor pollicis longus tendon may pre-sent with ‘Wartenberg’s syndrome’.
Maximizing the Yield of Black Cute Rice using Human Urine and NPK Fertilizer
Authors: Aziez Achmad Fatchul 
Published: September 2022

Background:
The nutrient is one of the most important elements for plants. Lack of nutrients cause thegrowth and yield will not be optimal. The use of organic liquid human urine and NPK fertilizer are a source of micro and macronutrients to increase the yield of black cute rice.

Objective:
This study aims to determine the best treatment combination of human urine and NPK fertilizer dose to maximize the yield of black cute rice.

Methods:
The research was arranged in a randomized complete block design (RCBD) with two factors and three replications. The first factor was dose of human urine fertilizer, which consisted of three levels, namely, 0, 500, and 1000 L ha-1. The second factor was the dose of NPK fertilizer, which consisted of three levels, namely, 0, 150, and 300 kg ha-1.

Results:
The results showed that a combination of organic liquid human urine and NPK fertilizer could increase the productive tillers number, canopy dry weight, and grain dry weight of black cute rice. The highest grain dry weight was found at the combination between ferlilizer dose of human urine of 1,000 L ha-1 and NPK of 300 kg ha-1 and yielded the maximum grain dry weight of 8.633 t ha-1 in Litosol soil.

Conclusion:
The research fundings that the combination between human urine of 1,000 L ha-1 and NPK of 300 kg ha-1 can maximize the yield of black cute rice. For future research, we recommend that the combination between human urine of 1,000 L ha-1 and NPK compound of 300 kg ha-1 can use in other rice varieties.
Botanische macroresten uit sloten als spiegel voor het landschap
Authors: Huiting Marjon , Spier Annisa , Schepers Mans 
Published: September 2022

Samples from ditches as a reflection of the landscape. Ditch-fill samples were taken from modern ditches in three different landscapes – the sandy heathland of Balloërveld, the peatland of Fochteloërveen and the woodland of Norg. This contribution focuses on the botanical macroremains collected from the ditch fills and how these remains may improve landscape-historical research. Microscopic research of the macroremains shows a difference between the habitats, albeit not a distinct one. Botanical remains of woodland vegetation were strongly represented in virtually all samples, overshadowing indicative species per landscape type. Given the limits of this pilot study, further research is strongly recommended to assess how ditch fills can be of value to reconstructing past and present landscapes.
De Zeehond of Fiducie? Uitsluitsel over de identiteit en ondergang van de bekendste tjalk van Flevoland
Authors: Van Popta Yftinus 
Published: September 2022

De Zeehond or Fiducie? New insights into the identity and date of foundering of Flevoland’s best known sailing barge shipwreck. This paper focuses on the late 19th-century wreck of a Groninger tjalk (sailing barge) that was discovered in the 1960s in the eastern part of Flevoland, near the city of Lelystad. During the excavation of the wreck (1972), two wooden battens were found that carried the inscriptions ’18 DE ZEEHOND 78’ and ‘W Venema 1878 A Koerts’. Soon it was concluded that the former carried the name and date of the ship and its construction, while the latter carried the names of the ship’s owners. Additional research revealed that the operators were identified as Willem Venema and Annegien Koerts from Hoogezand, Groningen. However, the archives failed to provide any information on a ship known as De Zeehond, whereas historical documents proved that Willem Venema did own a ship by the name of Fiducie. The current study answers the question whether the ship’s true name was De Zeehond or Fiducie, and provides new and more detailed insights into the ship’s career, date of foundering and crew history.
Ríos Ruiz, Alma de los Ángeles, Enseñanza del Derecho: Era Tecnológica, Electrónica y Digital, México, Editorial Flores, 2022,
Authors: Patiño Manffer Ruperto 
Published: September 2022

Recesión del libro "Enseñanza del Derecho: Era ecnológica, Electrónica y Digital" de la autora mexicana Alma de los Ángeles Ríos Ruiz.
El tráfico de hidrocarburos: un análisis químico-jurídico
Authors: García-Castillo Zoraida , Castillo-Alanís Alejandra 
Published: September 2022

<p>Este artículo tiene como propósito analizar, desde el punto de vista jurídico y científico, la resolución de asuntos de tráfico de hidrocarburos. Ello, a partir de cuatro sentencias dictadas en el contexto del sistema penal acusatorio en México, en casos similares de “huachicol”, en su modalidad de posesión y transporte de hidrocarburos, en forma ilícita. Este delito se analiza en juicio, principalmente sobre la base de la dictaminación de la química forense para la determinación de hidrocarburos. Las técnicas que se usan requieren de ser estandarizadas y clarificadas para su correcta aplicación, y deberían de ser conocidas por los juristas que intervienen en la resolución de los casos para tener mejores elementos de convicción sobre su calidad y confiabilidad, para la valoración en juicio. El diálogo entre la ciencia y el derecho se muestra indispensable. </p><div> </div>
La química y los grandes delitos ambientales
Authors: Cruz Núñez Xochitl 
Published: September 2022

<p>Los delitos ambientales son relevantes a escala planetaria debido a que agreden la salud y estabilidad de los ecosistemas y, en muchas instancias, los daños son irreversibles debido a la fragilidad de los ecosistemas. Al menos siete de los 17 objetivos del desarrollo sostenible están dirigidos a la salud en un ambiente sano. El artículo 4º de la Constitución Política de los Estados Unidos Mexicanos declara el derecho de todos los mexicanos a un “medio ambiente sano para su desarrollo y bienestar” y la penalización a quien deteriore el medio ambiente. </p><p>La normatividad mexicana contiene un grueso acervo de normas, leyes y reglamentos encaminados a proteger la salud ambiental y humana, así como la conservación de las especies. Uno de los problemas asociados con este cumplimiento es la coordinación y cumplimiento de múltiples instancias, principalmente gubernamentales, que puede resultar en una dispersión de responsabilidades. Un ejemplo es la calidad del aire. Si el aire está contaminado, ¿quién es responsable? Encontrar las causas de la contaminación permitirá asignar responsabilidades. Determinar la base científica es el papel del científico, en este caso, del químico de la atmósfera, y asignar la responsabilidad es el papel del que imparte justicia. </p><p>En esta contribución se presenta un estudio de caso en el que el conocimiento de la química permite entender el problema de la calidad del aire en Hermosillo, Sonora, debido a la denuncia presentada por un ciudadano. El conocimiento de las causas de la contaminación proporcionó las herramientas para dirigirse a los directamente responsables, en este caso, las autoridades municipales de Hermosillo.</p>
La dosis es el veneno
Authors: Antonio Chamizo José 
Published: September 2022

<p>La dosis es el veneno es una frase que se atribuye al famoso alquimista Paracelso y uno de los pocos conocimientos que hoy reconocemos como válidos provenientes de aquella época. Se presenta una breve biografía de dicho personaje además de una también breve historia de los venenos ubicándolos en el contexto actual y resaltando su importancia en la educación química.</p><div> </div>
Sifat Fisika Kayu Rajumas (Duabanga moluccana Blume) Berdasarkan Arah Aksial Dan Arah Radial Dari Desa Sambik Elen Kabupaten Lombok Utara
Authors: Wulandari Febriana Tri , Suastana I Made Wayan 
Published: September 2022

Pemanfaatan kayu kurang dikenal sudah banyak dilakukan untuk memenuhi kebutuhan kayu sebagai bahan baku. Kayu yang dimanfaatkan kebanyakan berasal dari jenis cepat tumbuh. Salah satu jenis kayu cepat tumbuh yang sifatnya belum banyak diketahui adalah kayu rajumas. Tujuan dari penelitian ini adalah untuk mengetahui nilai sifat fisika kayu rajumas (Duabanga moluccana Blume) dari Desa Sambik Elen, Lombok Utara serta mengetahui pengaruh interaksi arah aksial dan arah radial terhadap sifat fisika kayu rajumas (Duabanga moluccana Blume). Penelitian ini dilakukan menggunakan metode eksperimen yang dibuat dengan rancangan acak lengkap factorial dengan 2 faktor, yaitu arah aksial dan arah radial. Pembuatan contoh uji dan pengujian dilakukan mengikuti British Standard nomor 373 tahun 1957. Hasil penelitian dianalisis menggunakan software spss 24, kemudian diujilanjut menggunakan uji BNJ dengan taraf kepercayaan 5%. Hasil penelitian menunjukkan bahwa kadar air segar dan kering udara sebesar 140,09% dan 14,17%. Berat jenis segar, kering udara, dan kering tanur berurutan adalah 0,31, 0,32 dan 0,33. Interaksi arah aksial dan arah radial, faktor aksial berpengaruh nyata pada kadar air segar. Sementara faktor arah radial berpengaruh nyata terhadap hampir semua sifat fisika, kecuali kadar air kering udara.
TRADISI DAN BUDAYA TOLERANSI DALAM TINJAUAN SEJARAH DI ACEH
Authors: Nurlaila Nurlaila 
Published: September 2022

The discussion of tolerance has become a hot topic discussed in various studies, both in the form of writing and verbally through various dialogues and forums. Tolerance is an easy topic to discuss in sharing forums, but in its realization and application there is still a lot to learn. The problem of tolerance is a test in itself in society, because although there are many scientific studies that discuss the necessity and obligation of a culture of tolerance in society. But in reality tolerance is always a problem in realizing it. This sometimes becomes difficult in its realization because it is found that there are still many citizens, groups or even certain cultures who are intolerant in various ways. Aceh, an area that applies Islamic law in Indonesia, is a test in itself in implementing a culture of tolerance in Aceh. There were several cases that caused Aceh to become intolerant, starting from the DI/TII rebellion in 1953 which was intolerant of Indonesia, the displacement of other ethnic groups during GAM's burning of houses of worship in Aceh and various other cases that indicated that Aceh was intolerant. Seeing this reality, this study wants to see another angle on the problem of tolerance in Aceh. The author sees from the perspective of culture and history, Aceh is very tolerant in religious matters. So that in the course of Aceh's history they can live, do business, diplomacy and discuss with various religions.AbstrakPembahsan tentang toleransi menjadi topik yang hangat di bicarakan dalam berbagai kajian baik di berupa tulisan, maupun pembicaraan secara lisan lewat bergai dialog dan forum. Toleransi menjadi topik yang mudah untuk di bahas dalam berbagi forum namun dalam perwujudan dan aplikasinya masih harus terus banyak belajar. Masalah toleransi menjadi ujian tersendiri dalam masyarakat, karena meski banyak kajian ilmiah yang membahas harus, perlu dan wajibnya budaya toleransi dalam bermasyarakat. Namun kenyataannya toleransi selalu terjadi masalah dalam mewujudkan. Hal tersebut kadang menjadi susah dalam perwujudannya karena didapati masih banyak warga, kelompok atau bahkan budaya tertentu yang bersikap intoleran dalam berbahai hal. Aceh sebuah daerah yang menerapkan syariat Islam di Indonesia menjadi ujian tersendiri dalam menerapakan budaya toleransi di Aceh. Ada beberapa kasus yang menyebabkan Aceh menjadi in toleran mulai dari pemberontaka DI/TII tahun 1953 yang tidak toleran dengan Inonesia, pengusian etnis lain pada saat GAM pembak aran rumah ibadah di Aceh dan berbagai kasu lain yang mengindikasikan Aceh intoleran. Melihat realitas tersebut kajian ini ingin melihat sudut lain dari permasalah toleransi di Aceh. Penulis melihat dari kaca mata budaya dan sejarah dulu, Aceh sangat toleran dalam masalah agama. Sehingga dalam perjalanan sejarah Aceh bisa hidup, berbisnis, berdiplomasi dan berdiskusi dengan berbagai Agama.
Influence of Women Political Participation in Parliament Correlates to Gender Issues in Indonesia
Authors: SATRIS REZKI , RIZSA SABILLA KINANTI 
Published: September 2022

This paper discussed the influence of gender political participation in parliament in advocating gender issues. The quantity of women representation in parliament was increasing according to election contestation. Meanwhile, the concept of representation of women by adopting from Anne Philips mentioned that the presence of political representation occurred due to an imbalance between social classes men and women. Recently, there is evidence that women have a role in public. Thus, politic which interpreted as a presence of thinking could be a basis of political liberation for women in parliament by women activists to take a role in legislative. This paper deeply analyzes the influence of women advocating for gender issues. The research method used in this research was a qualitative approach to understanding the phenomena in the background of specific contextual. The result revealed that women have an influence on all policies form which correlates to women's issues through the promotion movement in the level of decision making. In the condition of women, roles could affect significantly on gender issues in Indonesia.
The power of language: The persuasiveness used in selected Philippines’ and Thailand’s tourism brochures
Authors: Santos Myla L. , Mukminin Amirul 
Published: September 2022

Linguistic features of tourism brochures can describe the distinctive ways of expressing persuasiveness in advertising which have a significant impact on teaching English as a foreign or second language. This study determined how linguistic features and functions characterize the advertising stance of the Philippines’ and Thailand’s tourism brochures. It sought to explore the fundamental contributions of linguistic forms and structures in these tourism brochures to facilitate persuasiveness. A collection of tourism brochures were randomly acquired online and coded for qualitative and quantitative analyses. However, only the verbal expressions were analyzed, disregarding other components of the brochures such as semiotics. The results show that the Philippines’ and Thailand’s brochures used rhyme in their lines minimally. Most of their lines were simple narratives and descriptive statements. There were instances of neologism but no anagrammatical structure. Structural parallelism in both brochures is evident. Thailand’s brochures used minor sentences more often than the Philippines’ brochures. Both showed a degree of informal styles. These informal styles suggested an easy-going social relationship between the audience and the advertisers. Based on the single verbs used, the Philippines’ tourism brochures capitalized on what the senses can experience and the enjoyment and satisfaction derived from such while Thailand’s tourism advertising brochures focused more on movement, both spatial and temporal. In terms of memorability, Thailand’s samples have very limited use of alliteration and metrical rhythm, while the Philippines’ samples were poetic and were fond of using alliteration.
Kill Venus! - Das in Männern und Frauen verratene Weibliche befreien
Authors: Bertola Lina 
Published: September 2022

Das Weibliche ist nicht «die Frau» – deshalb: Kill Venus! Stattdessen ist es ein Zugang zum Leben, der uns alle, Männer und Frauen, mit dem Kern unseres Menschseins verbindet. Die Autorin tritt dafür ein, diesen vor Jahrtausenden verratenen Wert zu befreien – für eine neue Kultur der Menschlichkeit.
Das Weibliche war lange – als Ausdruck ihrer Minderwertigkeit – in den Frauen gefangen. Seine Abwertung hat die Geschichte der Vernunft begleitet und Entscheidungen mitbestimmt, durch die sich die westliche Denkweise durchgesetzt hat. Die Krise unserer Zeit kann interpretiert werden als das Abdriften einer Rationalität, die das Denken und die Formen des Zusammenlebens dominiert. Das Weibliche erblühen zu lassen als neue Nahrung für unser In-der-Welt-Sein bedeutet, die symbolischen Käfige zu verlassen, die unsere Zivilisation erbaut hat, und im Weiblichen ein Prinzip zu erkennen, das wir alle zusammen pflegen müssen.
Prehabilitation Improves Knee Functioning Before and Within the First Year After Total Knee Arthroplasty: A Systematic Review With Meta-analysis
Authors: Gränicher Pascale , Mulder Loes , Lenssen Ton , Scherr Johannes , Swanenburg Jaap , de Bie Rob 
Published: September 2022

OBJECTIVE: To assess whether prehabilitation influenced knee functioning before and within the first year after total knee arthroplasty (TKA) surgery. DESIGN: Intervention systematic review with meta-analysis. LITERATURE SEARCH: The authors searched the MEDLINE/PubMED, EMBASE, CINAHL, Cochrane Library, Physiotherapy Evidence Database, Web of Science, and Scopus databases from their inception until March 2022. STUDY SELECTION CITERIA: The authors included peer-reviewed articles comparing preoperative, short-, mid- or long-term effects of exercise-based physical therapy before primary unilateral TKA with TKA without prehabilitation. DATA SYNTHESIS: We assessed bias using the Cochrane Risk-of-Bias tool (ROB 2.0) and therapeutic validity using the i-CONTENT tool. Standardized mean differences (Hedges' g) and 95% confidence intervals (CIs) were calculated for knee functioning. Certainty of evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. RESULTS: Sixteen trials (968 participants) were included; 14 qualified for meta-analysis. Low to very low certainty of evidence favored prehabilitation over no intervention for improving knee functioning before (g = 1.23; 95% CI: 0.49, 1.97) and up to 3 months after TKA (short-term: 1 day to 1 month, g = 0.90; 95% CI: 0.18, 1.61; mid-term: 6 weeks to 3 months, g = 0.45; 95% CI: 0.06, 0.84). There were no significant between-group differences at long-term follow-up (6–12 months, g = 0.07; 95% CI: −0.17, 0.30). CONCLUSION: There was low to very low certainty of evidence that prehabilitation promotes superior knee functioning before and up to 3 months after TKA, compared to TKA alone. The long-term postoperative effects were inconclusive. J Orthop Sports Phys Ther 2022;52(11):709–725 Epub: 20 September 2022. doi:10.2519/jospt.2022.11160
Assessment of oral care habits in patients with fixed dental prostheses: A pilot study
Authors: Alenezi Ali 
Published: September 2022

Objectives:
The aim of the present study was to evaluate patients’ oral care habits with fixed dental prostheses and the level of oral hygiene instructions they received from dental professionals.

Material and Methods:
A short questionnaire was created containing 12 questions and focusing on four main parts. The first part of the questions included patient demographic information while the remaining part assisted patient’s oral care habits and instructions that patients received from their dentists and dental hygienists.

Results:
The study population consisted of 259 patients in which 59% of them were female. Nearly 40% of the patients believed that they did not receive clear information and instructions from their dentists or hygienists on how to clean their fixed dental prosthesis. Although, most of them did visit their dentists and hygienists after they completed the fixed prosthesis treatment. Around 57% of the patients revealed that they did not try to seek information about the correct way of cleaning your fixed dental prosthesis. When they were asked about their cleaning habits of the fixed prosthesis, the majority reported that they use both toothbrush and flossing methods for cleaning.

Conclusion:
Most of patients with dental prosthesis believe they are lacking instructions about the proper method for optimal oral hygiene. Meanwhile, patients who believed that they received enough instructions with regard optimal oral hygiene can show better commitment toward daily oral care.
Le Trouble de Déficit de l’Attention et d’Hyperactivité (TDAH) de l’adulte : Quand certains symptômes en cachent d’autres.
Authors: Rio Benito Maria 
Published: September 2022

Le diagnostic de TDAH de l’adulte a été inclus dans la cinquième version du Manuel des Troubles Mentaux de l’Association Américaine de Psychiatrie (DSM5), en 2013. Ce diagnostic se réfère à un trouble neurodéveloppemental avec, comme symptômes cardinaux, l’inattention, l’hyperactivité et l’impulsivité. Les études mon­trent une prévalence de 5,29% pour les enfants, et de 2,5% pour les adultes entre 19 et 45 ans. Le taux de comorbidités chez les adultes diagnostiqués de TDAH est élevé. L’objectif de cet article est double : 1. l’exploration des pistes d’amélioration du processus diagnostic et thérapeutique du TDAH afin d’éviter un diagnostic tardif, et 2. Un regard rétrospectif sur le parcours des adultes diagnostiqués de TDAH en quête d’idées pour l’amélioration de la prise en charge familiale, scolaire et sociétale des enfants diagnostiqués de TDAH. Les données utilisées pour l’étude proviennent de deux sources : 1. les dossiers cliniques des patients de la file active de l’auteure pour lesquels le diagnostic de TDAH de l’adulte a été posé tardivement, et 2. de l’expérience propre des patients, obtenue via le remplissage volontaire d’un questionnaire anonyme présenté cidessous. Les données ont été analysées qualitativement. Les résultats montrent qu’un diagnostic précoce de TDAH et des comorbidités éventuelles apparaît comme la meilleure option pour orienter les choix de style de vie, de cursus académique et de travail les plus adaptés au fonctionnement de la personne.