bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Implementation of Notesmaster as a Learning Platform for Secondary Education - A Case of the Namibian College of Open Learning (NAMCOL)
Authors: Nitschke Jan Jacobus , Louw Wilhelmina 
Published: July 2022

The Namibian College of Open Learning (NAMCOL) is a government-funded educational institution that provides study opportunities to adults and out-of-school youth. NAMCOL has adopted the Notesmaster platform as a learning portal for its secondary education programme. This study aims to share the NAMCOL experience, in using Notesmaster as a preferred platform for OER in open schooling, including experiences of the content developers, tutors and learners. Data was gathered from learners, tutors and content developers to assess their involvement and determine to what extent the platform has contributed to their success in teaching and learning.
In documenting and sharing the successes and challenges experienced by NAMCOL, this paper could serve as a valuable resource to any Open Innovative School seeking to implement its own OER development programme and subsequent provision to learners and tutors.
Keywords: eLearning, Open Schooling, Open Educational Resources.
Teaching and Learning Experiences in Medical Education During the COVID-19 Pandemic: The Case of Kilimanjaro Christian Medical University College (KCMUCo), Tanzania
Authors: Ibrahim Glory , Luzinge Heavenlight , Kapanda Gibson 
Published: July 2022

Objective
The purpose of this paper was to share teaching and learning experiences during the COVID-19 pandemic and mandated university closure.
Methods
A cross-sectional study was conducted among all eligible students and faculty members using voluntary anonymous questionnaires. To capture the attitudes and perceptions of respondents, five-point Likert scale questions were used.
Results
A total of 865 (58%) students and 57 (51%) faculty members participated in the survey. Uptake of e-learning platforms increased by 15.4% for students, 43.0% for faculty and by 22.3% in courses. The overall students’ strength of consensus measure of perception on accessibility of platforms was 65% and support entities 79%. About 70% of students owned a smartphone as a learning device. More than 67% of the students highlighted the cost of Internet bundles as a major challenge.
Conclusion
Shifting from blended learning to online learning during the lockdown was feasible given the pre-planned e-learning practices.
Academic Silver Linings in a Philippine State University Amid the Early Stages of Pandemic Cases
Authors: Toquero Cathy Mae 
Published: July 2022

The primary role of the academe is knowledge building, however, due to the prevailing digital divide, some institutions of higher learning were not able to offer even Emergency Online Teaching (EOT) for continuous formal education during the early stages of the pandemic. This article highlights diversified ways that a state university from a developing country (Philippines) responded to the crisis to offer assistance towards the social development of the stakeholders amid the COVID-19 pandemic.
ИЗУЧЕНИЕ ФАРМАКОКИНЕТИКИ ГЕНТАМИЦИНА У КРЫС ПРИ ЛИМФОТРОПНОМ ПРЕТРАХЕАЛЬНОМ И ВНУТРИМЫШЕЧНОМ ВВЕДЕНИИ
Authors: Маматов Бахтияржон , Муминов Бахром , Кузиев Озодбек , Абдуллаев Азизбек , Собиров Мухаммаджон , Исмоилов Ойбек , Эргашев Хуршидбек , Хасанов Шокирхон , Атаханова Нилуфар 
Published: July 2022

Статья посвящена экспериментальному изучению на крысах фармакокинетики гентамицина при лимфотропном претрахеальном и внутримышечном способах введения. Приведены данные о концентрации антибиотика в крови и тканях органов дыхания крыс в динамике, показано, что метод лимфотропного претрахеального введения обеспечивает более высокие концентрации антибиотика в сравнении с внутримышечным способом. Высокую терапевтическую эффективность этого метода удается достичь, благодаря наличию связей между лимфатической системой, а также органами и тканями. Это обстоятельство позволяет доставлять лекарственный препарат к пораженному органу непосредственно. Помимо этого, в случае проведения лимфотропной терапии в очаге оптимальная концентрация лекарственного препарата сохраняется в течение 24 часов. Так что, нет необходимости в частом введении препарата (к примеру, при антибактериальной терапии), можно снизить курсовую и суточную дозы лекарственных препаратов. Лекарственное средство, которое введено лимфотропно, не способно оказывать токсическое воздействие на кишечник, почки, печень, так как в кровь попадает только мизерная часть препарата.
Penggunaan Alas Kaki Terhadap Tingkat Pengetahuan Siswa Sekolah Dasar Negeri 060873 Pulo Brayan Kota Medan
Authors: Putri Ajeng Nurika , Harahap Nurma Aini , Harahap Sefira Aulia , Yulia Silvia Ade , Rahmanda Syalwa Uzla 
Published: July 2022

Permasalahan yang sering terjadi pada anak sekolah belum memahami pentingnya penggunaan alas kaki. Penelitian ini menggunakan metode penelitian kuantitatif. Teknik pengambilan data dengan kuesioner yang diberikan kepada responden dan sebuah game cerdas cermat untuk menguji pemahaman siswa-siswi SD Negeri 060873 tentang pentingnya penggunaan alas kaki. Persentase pengetahuan siswa-siswi SD Negeri 060873 tentang penggunaan alas kaki yang didapatkan sebelum penyampaian promosi kesehatan adalah sebanyak 86,3% dari 100%. Dan setelah promosi kesehatan didapatkan 93,6% dari 100%. Dalam penyampaian materi promosi kesehatan ini, siswa-siswi antusias dalam melihat, mendengarkan, dan menanggapi materi dengan baik.Permasalahan yang sering terjadi pada anak sekolah belum memahami pentingnya penggunaan alas kaki. Penelitian ini menggunakan metode penelitian kuantitatif. Teknik pengambilan data dengan kuesioner yang diberikan kepada responden dan sebuah game cerdas cermat untuk menguji pemahaman siswa-siswi SD Negeri 060873 tentang pentingnya penggunaan alas kaki. Persentase pengetahuan siswa-siswi SD Negeri 060873 tentang penggunaan alas kaki yang didapatkan sebelum penyampaian promosi kesehatan adalah sebanyak 86,3% dari 100%. Dan setelah promosi kesehatan didapatkan 93,6% dari 100%. Dalam penyampaian materi promosi kesehatan ini, siswa-siswi antusias dalam melihat, mendengarkan, dan menanggapi materi dengan baik.
Gambaran Pengetahuan Dan Sikap Remaja Putri Kelas VII Tentang Menstruasi Di SMPN 2 Kapala Pitu Tahun 2018
Authors: Rapa Albertin 
Published: July 2022

Latar Belakang penulisan karya ilmiah Sebagian remaja sudah mengalami kematangan organ reproduksi dan dapat berfungsi atau bereproduksi, namun secara sosial dan mental mereka belum dewasa. Remaja akan mengalami banyak masalah jika pendidikan dan pengasuhan seksualitas dan reproduksinya terabaikan. Tujuan Penelitian adalah untuk mengetahui gambaran pengetahuan dan sikap remaja putri kelas VII tentang menstruasi di SMPN 2 KapalaPitu Kec. KapalaPitu, Kab. Toraja Utara Tahun 2018. Metode Penelitian yang digunakan adalah desain penelitian deskriptif dengan menggunakan tekhnik Non Probality Sampling dengan metode Purposive Sampling dengan jumlah 46 sampel. Data yang digunakan dalam penelitian ini adalah data primer, dengan variable di teliti adalah pengetahuan dan sikap siswa. Hasil Penelitian menunjukkan bahwa dari 46 siswi yang menjadi responden penelitian, terdapat 10 (21,74%) siswi yang pengetahuan kurang, 26 (56,52%) siswi yang pengetahuan cukup dan 10 (21,74%) siswi yang pengetahuan baik. Dan dari 46 siswi yang menjadi responden penelitian, terdapat 13 (28,26%) siswi yang bersikap negatif dan 33 (71,74%) siswi yang bersikap positif. Kesimpulan dan Saran dari penelitian ini adalah masih terdapat siswi di SMPN 2 KapalaPitu yang berpengetahuan kurang dan bersikap negatif tentang menstruasi sehingga diharapkan kepada Kepala Sekolah dan Guru di sekolah untuk bekerjasama dengan tenaga kesehatan agar dapat memberikan penyuluhan kesehatan khususnya tentang menstruasi.
Registered report: The effects of incentivized lies on memory
Authors: Riesthuis Paul , Otgaar Henry , Hope Lorraine , Mangiulli Ivan 
Published: July 2022

AbstractIn the current experiment, we examined the effects of self‐generated deceptive behavior on memory. Participants (n = 230) were randomly assigned to a “strong‐incentive to cheat” or “weak‐incentive to cheat” condition and played the adapted Sequential Dyadic Die‐Rolling paradigm. Participants in the “strong‐incentive to cheat” condition were incentivized to lie to avoid a financial penalty (i.e., punishment). Participants in the “weak‐incentive to cheat” could also choose to lie but the outcome was a prosocial one (i.e., benefit for unknown co‐participant). Two‐days later, memory for the die‐rolling event was assessed. A similar number of participants lied to avoid punishment as for prosocial reasons. Interestingly, we did not find evidence for unethical amnesia. However, participants who engaged in deceptive behavior, irrespective of their motives, produced more memory errors than honest participants. Although our results suggest that engaging in deceptive behavior does not lead to motivated forgetting, it can lead to memory errors.
Full‐Scale Field‐Free Spin‐Orbit Torque Switching in HoCo Structure with a Vertical Composition Gradient
Authors: Liu Long , Song Yuhang , Zhao Xiaotian , Liu Wei , Zhang Zhidong 
Published: July 2022

AbstractCurrent‐induced magnetization switching without the assistance of an in‐plane magnetic field by using the spin orbit torque (SOT) has attracted lots of attention for the novel energy‐efficient and nonvolatile spintronics devices. In this study, a full‐scale field‐free SOT switching in perpendicularly magnetized Ru/Pt/HoCo/Ru multilayers with a designed vertical composition gradient is reported. Through annealing the multilayers at 150 °C for 0–40 min, a structural change from a multilayer to an alloying structure with mixed distribution of Ho and Co is found. Simultaneously, the field‐free switching gradually turns from a full‐scale to a partial switching with the structural change. The multiple mechanisms brought by fabricating the HoCo layers with vertical composition gradient (including the non‐uniform Dzyaloshinskii–Moriya interaction (DMI), the defects, the inevitable lateral gradient, or the exchange bias effect along the thickness direction) lead to the deterministic field‐free switching. In addition, a detailed study on the stack of Ru/gradient HoCo/Ru shows that HoCo itself can also produce a certain amount of SOT to realize a partial switching in the absence of the in‐plane field. This work provides a route via engineering rare‐earth‐transition‐metal ferrimagnet to manipulate DMI and SOT for fully electrically controlled spintronics devices.
Nanoscale Writing of Gold Nanoparticle Assemblies at the Liquid‐Vapor Interface Using a Focused Electron Beam
Authors: Priesner Jamir , Kraus Tobias , de Jonge Niels 
Published: July 2022

AbstractThe electron beam of an environmental scanning electron microscope is used to manipulate gold nanoparticles (AuNPs) at the liquid‐vapor interface of their aqueous dispersion. Controlled motion and agglomeration of AuNPs into larger structures is achieved, enabling the writing of superstructures that float at the interface. AuNPs move toward the electron beam, independent of zeta potential, and the spatial range at which this attraction acts is much larger than what is possible for electrostatic interactions. The speed of agglomerate growth depends on the applied electron flux, and electron beam energy. The hypothesis that this electron beam‐induced AuNP assembly process is caused by local liquid evaporation upon electron beam heating is presented.
Weak Localization Enhanced Ultrathin Scattering Media
Authors: Pompe Ruben C. R. , Meiers Dominic T. , Pfeiffer Walter , von Freymann Georg 
Published: July 2022

AbstractThe brilliant white appearance of ultrathin scattering media with low refractive index contrast and the underlying radiative transport phenomena fascinate scientists for more than a decade. Examples of such systems are the scales of beetles of the genus Cyphochilus, photonic network structures or disordered Bragg stacks (DBS). While previous studies relate the highly efficient scattering in the scales to the anisotropy of the intra‐scale network and diffusive light transport, the coherent radiation propagation dynamics remains unaccounted for. Here, the identification of different coherent light transport regimes using time and spatially resolved coherent light scattering spectroscopy is shown. At least 20% of the collected scattered light originates from weakly localized random photonic modes, in contrast to solely diffusive light transport assumed to date. The identification of this significant role of weak localization in ultrathin brilliant scattering media establishes a new design paradigm for efficient scattering optical materials.
Novel and High‐Sensitive Primary and Self‐Referencing Thermometers Based on the Excitation Spectra of Lanthanide Ions
Authors: de Souza Keyla M. N. , Silva Rodolfo N. , Silva Juliana A. B. , Brites Carlos D. S. , Francis Biju , Ferreira Rute A. S. , Carlos Luís D. , Longo Ricardo L. 
Published: July 2022

AbstractRemote sensing through ratiometric luminescence thermometry based on trivalent lanthanide ions (Ln(III)) has lately become a promising technique due to its numerous applications. Most available Ln(III)‐based luminescent thermometers require a calibration process with a reference thermal probe (secondary thermometers) and recurrent calibrations are mandatory, particularly when the thermometers are used in different media. This is sometimes impractical and a medium‐independent calibration relation is postulated, which is potentially inaccurate. Thus, the determination of the temperature based on well‐grounded physical principles by primary thermometers is the only way to overcome these challenges. Despite being considered one of the most important developments in luminescence thermometry, primary luminescent thermometers are scarce. Primary thermometers requiring calibration are proposed, implemented, and validated at one known temperature (primary‐T), which are also self‐referencing, employing ratiometric data from the excitation spectrum of Ln(III). By combining with the emission spectrum, thermometers not requiring calibration (primary‐S) are devised. An Eu(III)‐β‐diketonate complex is used as a proof‐of‐concept, but the approach is universal and other Ln(III)‐based materials can be explored. Because many thermometric parameters are employed for temperature prediction an unprecedented very high accuracy of 0.2% in the physiological range is obtained.
Novel DZ‐SIM Conjugate Targets Cancer Mitochondria and Prolongs Survival in Pancreatic Ductal Adenocarcinoma
Authors: Ou Yan , Wang Ruoxiang , Chu Gina Chia‐Yi , Elmadbouh Omer Hany Miligy , Lim Adrian , Chung Leland Wei‐Kuo , Edderkaoui Mouad , Zhang Yi , Pandol Stephen Jacob 
Published: July 2022

AbstractPancreatic ductal adenocarcinoma (PDAC) is a disease with no effective therapeutics. A novel targeted therapy drug consisting of a tumor‐targeting ligand, near‐infrared (NIR) organic heptamethine carbocyanine dye (DZ), and HMG‐CoA inhibitor simvastatin (SIM), is developed and its efficacy in PDAC is assessed. PDAC cell specific targeting of DZ‐SIM is measured by determining the fluorescence in cells and animals. Mitochondrial bioenergetics and functions are measured by Seahorse and flow cytometry, respectively. Apoptosis is assessed by DNA fragmentation, annexin V/propidium iodide staining, and TUNEL. Markers of cell invasion, epithelial‐to‐mesenchymal transition, and cancer stemness are measured. The effect of DZ‐SIM on survival, tumor growth, and metastasis is measured in the Krasþ/LSLG12D;Trp53þ/LSLR172H;Pdx‐1−Cre transgenic mice and in syngeneic and subcutaneous PDAC models. NIR fluorescence imaging shows specific localization of DZ‐SIM to cancer, but not to normal cells and tissues. DZ‐SIM significantly inhibits tumor growth and re‐sensitizes therapeutically resistant PDAC cells to conventional therapies. DZ‐SIM kills cancer cells through unique pathways involving decreasing mitochondrial bioenergetics, including oxygen consumption and ATP production, and increasing ROS production. Mitochondrial depletion prevents the effect of DZ‐SIM. Administration of DZ‐SIM in three PDAC animal models results in a marked increase in survival and a decrease in tumor growth and metastasis.
3D Generation of Multipurpose Atomic Force Microscopy Tips
Authors: Glia Ayoub , Deliorman Muhammedin , Qasaimeh Mohammad A. 
Published: July 2022

AbstractIn this work, 3D polymeric atomic force microscopy (AFM) tips, referred to as 3DTIPs, are manufactured with great flexibility in design and function using two‐photon polymerization. With the technology holding a great potential in developing next‐generation AFM tips, 3DTIPs prove effective in obtaining high‐resolution and high‐speed AFM images in air and liquid environments, using common AFM modes. In particular, it is shown that the 3DTIPs provide high‐resolution imaging due to their extremely low Hamaker constant, high speed scanning rates due to their low quality factor, and high durability due to their soft nature and minimal isotropic tip wear; the three important features for advancing AFM studies. It is also shown that refining the tip end of the 3DTIPs by focused ion beam etching and by carbon nanotube inclusion substantially extends their functionality in high‐resolution AFM imaging, reaching angstrom scales. Altogether, the multifunctional capabilities of 3DTIPs can bring next‐generation AFM tips to routine and advanced AFM applications, and expand the fields of high speed AFM imaging and biological force measurements.
High‐Performance Flexible Sulfur Cathodes with Robust Electrode Skeletons Built by a Hierarchical Self‐Assembling Slurry
Authors: Zhang Zhengmin , Mo Jiangyang , Yu Peng , Feng Lanxiang , Wang Yu , Lu Yuyuan , Yang Wei 
Published: July 2022

AbstractThe electrochemical performance of lithium–sulfur batteries is fundamentally determined by the structural and mechanical stability of their composite sulfur cathodes. However, the development of cost‐effective strategies for realizing robust hierarchical composite electrode structures remains highly challenging due to uncontrollable interactions among the components. The present work addresses this issue by proposing a type of self‐assembling electrode slurry based on a well‐designed two‐component (polyacrylonitrile and polyvinylpyrrolidone) polar binder system with carbon nanotubes that forms hierarchical porous structures via optimized water‐vapor‐induced phase separation. The electrode skeleton is a highly robust and flexible electron‐conductive network, and the porous structure provides hierarchical ion‐transport channels with strong polysulfide trapping capability. Composite sulfur cathodes prepared with a sulfur loading of 4.53 mg cm−2 realize a very stable specific capacity of 485 mAh g−1 at a current density of 3.74 mA cm−2 after 1000 cycles. Meanwhile, a composite sulfur cathode with a high sulfur loading of 14.5 mg cm−2 in a lithium–sulfur pouch cell provides good flexibility and delivers a high capacity of 600 mAh g−1 at a current density of 0.72 mA cm−2 for 78 cycles.
Increases in vein length compensate for leaf area lost to lobing in grapevine
Authors: Migicovsky Zoë , Swift Joel F. , Helget Zachary , Klein Laura L. , Ly Anh , Maimaitiyiming Matthew , Woodhouse Karoline , Fennell Anne , Kwasniewski Misha , Miller Allison J. , Cousins Peter , Chitwood Daniel H. 
Published: July 2022

AbstractPremiseLeaf lobing and leaf size vary considerably across and within species, including among grapevines (Vitis spp.), some of the best‐studied leaves. We examined the relationship between leaf lobing and leaf area across grapevine populations that varied in extent of leaf lobing.MethodsWe used homologous landmarking techniques to measure 2632 leaves across 2 years in 476 unique, genetically distinct grapevines from five biparental crosses that vary primarily in the extent of lobing. We determined to what extent leaf area explained variation in lobing, vein length, and vein to blade ratio.ResultsAlthough lobing was the primary source of variation in shape across the leaves we measured, leaf area varied only slightly as a function of lobing. Rather, leaf area increases as a function of total major vein length, total branching vein length, and vein to blade ratio. These relationships are stronger for more highly lobed leaves, with the residuals for each model differing as a function of distal lobing.ConclusionsFor leaves with different extents of lobing but the same area, the more highly lobed leaves have longer veins and higher vein to blade ratios, allowing them to maintain similar leaf areas despite increased lobing. These findings show how more highly lobed leaves may compensate for what would otherwise result in a reduced leaf area, allowing for increased photosynthetic capacity through similar leaf size.
Indefinite linear quadratic optimal control for discrete time‐varying linear rectangular descriptor systems
Authors: Li Yichun , Ma Shuping 
Published: July 2022

AbstractIn this article, the indefinite linear quadratic (LQ) optimal control problem for discrete time‐varying rectangular descriptor systems is investigated, in which the indefinite weight matrices are considered in the quadratic cost function. With a suite of equivalent transformations, the indefinite LQ problem for discrete time‐varying rectangular descriptor systems can be substituted by an equivalent indefinite LQ problem for standard state space systems. Then, the transformed equivalent indefinite LQ problem is solved by establishing a dual Krein space model, and the optimal control and optimal cost value are obtained by invoking the Kalman filter of Krein space. The form of state feedback optimal control corresponding to the original system is given. Next, to guarantee the dynamic part for the resulting optimal closed‐loop system has a unique solution, some necessary and sufficient conditions are proposed. Finally, a numerical example is carried out to demonstrate the availability of established results.
Large papillary thyroid cancer bed recurrence causing overlying skin ulceration and bleeding
Authors: Boulas Konstantinos A. , Nathanailidou Maria , Sitaridis Konstantinos , Filippidis Isaac , Tsiariglis Ioannis , Domi Iliana , Hatzigeorgiadis Anestis , Jalalabadi Narjes Zarei 
Published: July 2022

AbstractSalvage surgery is an acceptable option for palliative treatment of thyroid bed recurrence in metastatic papillary thyroid carcinoma when other non‐invasive options fail to control local skin complications.
Fulminant hepatitis following COVID‐19 vaccination: A case report
Authors: Barary Mohammad , Sharifi‐Razavi Athena , Rakhshani Nasser , Sio Terence T. , Ebrahimpour Soheil , Baziboroun Mana 
Published: July 2022

AbstractThe common side effects of COVID‐19 vaccination were mostly self‐restricted local reactions that quickly resolved. Nevertheless, rare autoimmune hepatitis cases have been reported in some vaccinated with mRNA COVID‐19 vaccines. This article presents a young man who developed fulminant hepatitis a few days after vaccination with the first dose of the AstraZeneca COVID‐19 vaccine. A 35‐year‐old man was admitted to our hospital with generalized weakness, abdominal pain, and jaundice. He received the first dose of the AstraZeneca COVID‐19 vaccine 8 days earlier. He was admitted to the hospital with a chief complaint of abdominal pain. On admission and because of his high D‐dimers, low platelet count, and low Fibrinogen level, vaccine‐induced immune thrombosis thrombocytopenia was suspected, which was ruled out later. Then, after a surge in his liver function tests, decreasing platelet, and abnormal clotting tests, fulminant hepatitis was considered for this patient. Several bacterial, viral, and autoimmune etiologies were then suspected, with all ruled out. Thus, fulminant hepatitis secondary to his AstraZeneca COVID‐19 vaccine was confirmed. Unfortunately, he died 3 days later of disseminated intravascular coagulopathy, after which a liver necropsy was performed, indicating drug/toxin‐induced hepatitis.