bluuebunny/crossref_metadata_2025_split huggingface dataset:
Urban blue–green space landscape ecological health assessment based on the integration of pattern, process, function and sustainability
Authors: Song Shuang , Wang Shaohan , Shi Mengxi , Hu Shanshan , Xu Dawei 
Published: May 2022

AbstractLandscape ecological health (LEH) assessment of blue–green space is vital for the management and restoration of the urban environment. At present, existing LEH assessment research has mainly focused on the single measurement of landscape pattern or external ecological service function, ignoring the effect mechanism. Moreover, there is a lack of targeted assessment of urban blue–green space LEH. In this study, we constructed an urban blue–green space LEH assessment framework based on the integration of pattern, process, function and sustainability, and conducted an empirical analysis in Harbin, a megacity in Northeastern China. The results showed that the spatial changes in the four assessment units of landscape ecological pattern, process, function and sustainability were not coordinated in the study area. From 2011 to 2020, the overall condition of blue–green space LEH in the study area improved but still at an unhealthy level, and the spatial difference increased. Grassland, water and wetland suffered from the widespread degradation of LEH in the study area, and the LEH level improvement type had the largest area proportion, and the stabilization type had the smallest. Moreover, based on the spatial autocorrelation analysis, we clarified the LEH spatial correlation characteristics of the study area and proposed targeted optimization suggestions. Our assessment framework will extend the LEH assessment scope and methodology, and the research results can provide significant references for urban blue–green space protection and management.
Effects of bone turnover status on the efficacy and safety of denosumab among haemodialysis patients
Authors: Hori Mayuko , Yasuda Kaoru , Takahashi Hiroshi , Kondo Chika , Shirasawa Yuichi , Ishimaru Yuka , Sekiya Yuka , Morozumi Kunio , Maruyama Shoichi 
Published: May 2022

AbstractDenosumab is reported to increase bone mineral density (BMD) among haemodialysis patients; however, hypocalcaemia is a serious adverse effect among chronic kidney disease (CKD) patients. Identifying which patients will show greater improvement in BMD is important. We enrolled 84 haemodialysis patients with osteoporosis in our study. 28 patients initiated denosumab treatment between October 2019 and October 2020. We assessed BMD changes and investigated the association between baseline bone turnover marker (BTM) levels and 6-month changes in BMD after denosumab treatment. BMD was increased at 6 months in denosumab-treated patients compared with patients not treated with denosumab (lumbar spine: 5.34% vs. − 0.49%; total hip: 2.43% vs. − 0.47%). Bone-specific alkaline phosphatase (BAP) and tartrate-resistant acid phosphatase-5b (TRACP-5b) at baseline were independently associated with increased BMD in the total hip (BAP: β = 0.472, p value = 0.004; TRACP-5b: β = 0.433, p value = 0.008) and lumbar spine (BAP: β = 0.591, p value = 0.001; TRACP-5b: β = 0.613, p value = 0.0008). BAP and TRACP-5b were also independent predictors of hypocalcaemic events (OR [95% CI] 1.747 [1.084–4.604] and 1.006 [1.000–1.015], respectively). BTMs may be associated with increased BMD and hypocalcaemic events after denosumab treatment. BTM measurement may be useful for assessing the effect of denosumab on BMD; however, careful monitoring of serum calcium levels is needed.
Effect of self-managed lifestyle treatment on glycemic control in patients with type 2 diabetes
Authors: Dwibedi Chinmay , Mellergård Emelia , Gyllensten Amaru Cuba , Nilsson Kristoffer , Axelsson Annika S. , Bäckman Malin , Sahlgren Magnus , Friend Stephen H. , Persson Sofie , Franzén Stefan , Abrahamsson Birgitta , Carlsson Katarina Steen , Rosengren Anders H. 
Published: May 2022

AbstractThe lack of effective, scalable solutions for lifestyle treatment is a global clinical problem, causing severe morbidity and mortality. We developed a method for lifestyle treatment that promotes self-reflection and iterative behavioral change, provided as a digital tool, and evaluated its effect in 370 patients with type 2 diabetes (ClinicalTrials.gov identifier: NCT04691973). Users of the tool had reduced blood glucose, both compared with randomized and matched controls (involving 158 and 204 users, respectively), as well as improved systolic blood pressure, body weight and insulin resistance. The improvement was sustained during the entire follow-up (average 730 days). A pathophysiological subgroup of obese insulin-resistant individuals had a pronounced glycemic response, enabling identification of those who would benefit in particular from lifestyle treatment. Natural language processing showed that the metabolic improvement was coupled with the self-reflective element of the tool. The treatment is cost-saving because of improved risk factor control for cardiovascular complications. The findings open an avenue for self-managed lifestyle treatment with long-term metabolic efficacy that is cost-saving and can reach large numbers of people.
A framework for multiplex imaging optimization and reproducible analysis
Authors: Eng Jennifer , Bucher Elmar , Hu Zhi , Zheng Ting , Gibbs Summer L. , Chin Koei , Gray Joe W. 
Published: May 2022

AbstractMultiplex imaging technologies are increasingly used for single-cell phenotyping and spatial characterization of tissues; however, transparent methods are needed for comparing the performance of platforms, protocols and analytical pipelines. We developed a python software, mplexable, for reproducible image processing and utilize Jupyter notebooks to share our optimization of signal removal, antibody specificity, background correction and batch normalization of the multiplex imaging with a focus on cyclic immunofluorescence (CyCIF). Our work both improves the CyCIF methodology and provides a framework for multiplexed image analytics that can be easily shared and reproduced.
Mycelium polysaccharides of Macrolepiota procera alleviate reproductive impairments induced by nonylphenol
Authors: Wang Wenshuai , Li Xiaoxu , Zhang Yaohan , Zhang Jianjun , Jia Le 
Published: May 2022

Mycelium polysaccharides of Macrolepiota procera (MMP) had positive role in amelioration of NP-induced reproductive disorders.
Tailor-made urethane-linked alkyl-celluloses: a promising stabilizer for oil-in-oil Pickering emulsions
Authors: Tan Jiaojun , Ruan Shaowei , Zhang Meiyun , He Hui , Song Shunxi , Yang Bin , Nie Jingyi , Zhang Qiuyu 
Published: May 2022

A series of urethane-linked alkyl-cellulose was efficiently fabricated and served as a promising stabilizer for oil-in-oil Pickering emulsions.
The influences of silane coupling agents on the heat and moisture resistance of basalt fibre‐reinforced composites
Authors: Liu Yunpeng , Zhang Mingjia , Liu Hechen , Sun Yu , Wang Wanxian , Liu Jie 
Published: May 2022

AbstractBasalt fibre composite materials have shown good application prospects in electrical equipment, but their reliability can be affected by damp‐heat ageing. In this work, the interface, mechanical, and electrical properties of basalt fibre composites treated with three coupling agents via damp‐heat ageing were compared. Molecular simulations were conducted to reveal the damp‐heat ageing mechanism of the composites. The results show that γ‐aminopropyl triethoxy silane (KH‐550) and γ‐glycidoxy propyl trimethoxy silane (KH‐560) perform better as coupling agents as they form bonds with the matrix resin, compared with γ‐methacryloxy propyl trimethoxy silane (KH‐570). After the damp‐heat ageing treatment, the hydrolysis of the defects of the amino groups in the interface of the KH‐550‐treated sample can weaken its mechanical properties and insulation properties greatly. The interface layer of the KH‐560‐treated sample is mostly composed of carbon–oxygen single bonds and methylene groups with its interface structure more stable, which endows the sample with better stability of its mechanical and insulating properties. Therefore, KH‐560 is a more suitable coupling agent for processing basalt fibres to be used in electrical equipment.
New technique for determining a pulsar period: Waterfall principal component analysis
Authors: Cassanelli T. , Naletto G. , Codogno G. , Barbieri C. , Verroi E. , Zampieri L. 
Published: May 2022

Aims. This paper describes a new technique for determining the optimal period of a pulsar and consequently its light curve.
Methods. The implemented technique makes use of the principal component analysis (PCA) applied to the so-called waterfall diagram, which is a bidimensional representation of the acquired data of the pulsar. In this context, we have developed the python package pywpf to easily retrieve the period with the presented method.
Results. We applied this technique to sets of data of the brightest pulsars in visible light that we obtained with the fast photon counter Iqueye. Our results are compared with those obtained by different and more classical analyses (e.g., epoch folding), showing that the periods so determined agree within the errors, and that the errors associated with the waterfall-PCA folding technique are slightly smaller than those obtained by the x2 epoch-folding technique. We also simulated extremely noisy situations, showing that by means of a new merit function associated with the waterfall-PCA folding, it is possible to become more confident about the determined period with respect to the x2 epoch-folding technique.
Sicherheit und Effektivität der oralen Antikoagulation bei Vorhofflimmern und Niereninsuffizienz im Praxisalltag
Authors: Zeymer Uwe , Bonnemeier Hendrik , Wanner Christoph 
Published: May 2022

ZusammenfassungDie momentanen Leitlinien empfehlen Nicht-Vitamin-K-abhängige orale Antikoagulanzien (NOAK) als Therapiestandard für die Schlaganfallprophylaxe bei Patienten mit Vorhofflimmern (VHF) und sind daher den Vitamin-K-Antagonisten (VKA) vorzuziehen. Diese Empfehlung gilt auch für Patienten mit VHF und chronischer nicht dialysepflichtiger Niereninsuffizienz. Sogenannte Real-World-Evidenz (RWE), also Daten aus der klinischen Praxis, erweitert und bestätigt die zugrunde liegende klinische Evidenz, die in den stärker formalisierten klinischen Prüfungen mit NOAK und VKA, hier ausschließlich Warfarin, gewonnen wurde. Darüber hinaus zeigte die RWE, dass die Überlegenheit der NOAK gegenüber dem VKA Warfarin auch für Phenprocoumon gilt, dem in Deutschland gebräuchlichsten VKA. Auch fanden sich Hinweise, dass bei Patienten mit chronischen Nierenerkrankungen das Fortschreiten der Nierenfunktionsstörung unter Behandlung mit NOAK geringer ausfallen kann als unter VKA.
The Future of Visual Documentation? Assessing the Use of Videography in Facial Plastic Surgery
Authors: Soares Danny , Yamamoto Kyle , Liebertz Daniel 
Published: May 2022

AbstractRecent technological advancements in the field of portable electronics have facilitated the use of videography as a form of visual documentation in facial plastic surgery. Currently, the degree of video adoption and perceptions relating to its use in plastic surgery are not known. This study aimed to evaluate the current use, perceptions, and barriers regarding the adoption of video in the clinical practice of facial plastic surgery. A cross-sectional study of all American Academy of Facial Plastic and Reconstructive Surgery members was conducted through an e-mail-disseminated 24-item online survey. A total of 164 surgeons responded to the survey. Nearly all surgeons reported routinely employing photography for the documentation and marketing of surgical results. Fewer than 25% of respondents acknowledged using video to document surgical outcomes. Younger surgeons (<10 years in practice) and those in academic practices were significantly more likely to adopt videography (32 vs. 17%, p = 0.042 and 38 vs. 18%, p = 0.027, respectively). Most surgeons regarded video as the superior visual documentation format for dynamic facial expression and as being more difficult to deceptively manipulate. Most frequently cited barriers to adoption included time-consuming capture, file editing/storage requirements, and lack of clear standards. Videography holds favorable potential as the future format of visual documentation in facial plastic surgery due to its ability to capture the full range of dynamic facial expression. Establishing standards and setup guidelines for video capture will be essential in increasing its adoption.
A proposed unified mitotic chromosome architecture
Authors: Sedat John , McDonald Angus , Kasler Herbert , Verdin Eric , Cang Hu , Arigovindan Muthuvel , Murre Cornelis , Elbaum Michael 
Published: May 2022

Significance
The significance of this proposed mitotic chromosome architecture is that a specific, sequenced chromosome, human chromosome 10, can be built into a specific architecture that accounts for the dimensional values and cytological descriptions. Since this molecular architecture is an extension of the interphase chromosome structure, a coiling of the 11-nm nucleosome fiber with further coiling, a unifying molecular structure motif is present throughout the entire mitotic cycle, interphase through mitosis.
TRPC4 and GIRK channels underlie neuronal coding of firing patterns that reflect Gq/11–Gi/ocoincidence signals of variable strengths
Authors: Tian Jin-bin , Yang Jane , Joslin William C. , Flockerzi Veit , Prescott Steven A. , Birnbaumer Lutz , Zhu Michael X. 
Published: May 2022

SignificanceNeurons communicate by releasing neurotransmitters, many of which act at G protein–coupled receptors. Although it is well known that Gq/11accelerates action potential firing while Gi/oinhibits firing, how firing patterns change in response to simultaneous activation of Gq/11and Gi/oremains elusive, especially because the relative strength of Gq/11versus Gi/oactivation varies greatly from event to event. This study reveals that neurons encode distinct messages that reflect coincident Gq/11and Gi/ostimulation by activating two ion channels, TRPC4 and GIRK. The resulting firing patterns, composed of burst, pause, and firing recovery phases, reflect both the occurrence of coincident Gq/11and Gi/oactivation and their relative strengths. With these, we may begin to interpret the language of neurons.
Using music in a word stress processing task
Authors: Degrave Pauline 
Published: May 2022

Abstract
Previous studies have reported that the use of music-related activities (e.g. hand-clapping or songs) can help
learners to acquire foreign languages. It remains unclear, however, whether music-based approaches help every learner equally or
whether it is more beneficial for learners with a musical background, such as musical practice, musical abilities, or engagement
in musical activities. In order to answer this question, we tested 80 French speakers whose musical background was evaluated using
a questionnaire. They performed a word stress processing task in Dutch containing spoken stimuli, spoken stimuli with a beat, or
sung stimuli. The results show that learners with some musical characteristics obtain higher scores than other learners and that
the use of music in the task can favor learners with a musical background.
Z-scheme SnC/HfS2 van der Waals heterojunction increases photocatalytic overall water splitting
Authors: Dai Zhuo-Ni , Cao Yong , Yin Wen Jin , Sheng Wei , Xu Ying 
Published: May 2022

Abstract
Designing a direct Z-scheme system is one of the effective ways to develop a high-efficient photocatalyst. In this paper, we designed the SnC/HfS2 heterojunction and explored its electronic structure and photocatalytic properties for water splitting based on first-principles calculations. Our results suggest that SnC/HfS2 heterostructure is a typical direct Z-scheme heterojunction, which can effectively separate carriers and possesses strong oxidation and reduction capabilities. The valence band maximum of SnC is close to the conduction band minimum of HfS2, which is in favor of the recombination of inter-layer carriers. The very small interlayer band gap and appropriate built-in electric field direction make the migration of electrons and holes along the Z-path. The photo-generated electrons on SnC make the hydrogen evolution reaction happen continuously, while the photo-generated holes on HfS2 make the oxygen evolution reaction happen continuously. The calculation of the reaction energy barrier indicates that the procedure of photocatalytic water splitting on the SnC/HfS2 heterojunction can be spontaneous. Our results show that SnC/HfS2 heterojunction is a potential direct Z-scheme photocatalyst for the overall decomposition of water.
A comparison study of the born-kuhn model and the finite-difference-time-domain calculations on stacked plasmonic nanorods
Authors: Karimitari Nima , Ai Bin , Zhao Yiping 
Published: May 2022

Abstract
A detailed analysis of the Born-Kuhn (BK) model for two coupled oscillators and comparison to the chiral optical properties of the corner-stacked plasmonic nanorods (CSPNs) have been investigated. Based on the normalized coupling constant c (= coupling frequency

ω
c

/resonance frequency

ω
0

) and the damping constant g (= dissipation γ/

ω
0

), the chiral optical response of the BK model could be significantly different, and the c-g space can be divided into two phase regions, a weak coupling and a strong coupling region. Once the c and g parameters are extracted from CSPN structures based on finite-difference time domain (FDTD) calculations, the BK model can be directly applied to predict the chiral plasmonic response of the CSPNs. In particularly, at

c
=

g

, the BK model suggests the strongest optical rotation dispersion while stronger circular dichroism occurs with a small g and a large c. These predictions have been confirmed by the FDTD calculations of CSPN structures. The detailed analysis of the BK model and the use of the model to direct fit the optical property of CSPNs demonstrate that the BK model is a very versatile class model to predict the chiral response of a chiral plasmonic structure or help to design and optimize a specific chiral plasmonic structure for a specific application.
Floquet topological phases with high Chern numbers in a periodically driven extended Su–Schrieffer–Heeger model
Authors: Agrawal Aayushi , Bandyopadhyay Jayendra N 
Published: May 2022

Abstract
The high Chern number phases with the Chern number |C| > 1 are observed in this study of a periodically driven extended Su–Schrieffer–Heeger (E-SSH) model with a cyclic parameter. Besides the standard intra-dimer and the nearest-neighbor inter-dimer hopping of the SSH model, an additional next-nearest-neighbor hopping is considered in the E-SSH model. The cyclic parameter, which plays the role of a synthetic dimension, is invoked as a modulation of the hopping strengths. A rigorous analysis of different phase diagrams has shown multiple Floquet topological phase transitions among the high Chern number phases. These phase transitions can be controlled by the strength and frequency of the periodic driving. Instead of applying perturbation theory, the whole analysis is done by Floquet replica technique. This gives a freedom to study high as well as low-frequency effects on the system by considering less or more number of photon sectors. This system can be experimentally realized through a pulse sequence scheme in the optical lattice setup.
Statistical terrain model with geometric feature detection based on GPU using LiDAR on vehicles
Authors: Liu Bo , Zhao Dingxuan , Chang Jinming , Yao Shuangji , Ni Tao , Gong Mingde 
Published: May 2022

Abstract
Digital terrain models based on light detection and ranging (LiDAR) are widely used in ground robots to achieve autonomous navigation. Very few studies have been conducted on terrain modelling for preview information, which acts as an input for a vehicle’s active suspension system. In this study, we proposed an algorithm to construct a real-time terrain model from multi-frame LiDAR points according to the applications for preview control. The terrain model consisted of an elevation map with confidence intervals and feature detection. First, the statistical confidence interval of the elevation map represented the reliability of the mean height. Further, we used spatial signal processing techniques to detect the uneven geometric features of the terrain. The key point feature on the trajectory was detected by the Laplacian of Gaussian method. Finally, the raw point cloud data processing procedure was based on parallel multi-thread techniques combined with GPU programming, which significantly promotes computation efficiency to enable real-time implementation. Thus, the proposed terrain model integrates reliability issues and geometric features, which act as inputs for preview controllers or motion planning. Experimental results proved that our method has a competitive performance (in terms of precision and efficiency) compared with the state-of-the-art methods, and runs in real-time at 50 Hz.
Identification of texture characteristics for improved creep behavior of a L-PBF fabricated IN738 alloy through micromechanical simulations
Authors: Prasad Mahesh R G , Biswas Abhishek , Vajragupta Napat , Hartmaier Alexander 
Published: May 2022

Abstract
Additive manufacturing (AM) of nickel-based superalloys, due to high temperature gradients during the building process, typically promotes epitaxial growth of columnar grains with strong crystallographic texture in form of a 〈001〉 fibre or a cube texture. Understanding the mutual dependency between AM process parameters, the resulting microstructure and the effective mechanical properties of the material is of great importance to accelerate the development of the manufacturing process. In this work, a multi-scale micromechanical model is employed to gain deeper insight into the influence of various texture characteristics on the creep behavior of an IN738 superalloy. The creep response is characterized using a phenomenological crystal plasticity creep model that considers the characteristic γ–γ′ microstructure and all active deformation mechanisms. The results reveal that the creep strength increases with decreasing texture intensities and reaches its maximum when the 〈001〉 fibre and cube textures are misaligned to the specimen building direction by 45°. The simulations also predict that the uncommon 〈111〉 and 〈110〉 fibres offer significantly higher creep resistance than the typically observed 〈001〉 fibre, which provides a further incentive to investigate AM processing conditions that can produce these unique textures in the material. As the intensities and the alignment of 〈001〉 fibre and cube textures can be attributed to the laser energy density and the scan strategy employed and as the formation of distinct fibre textures depends on the geometry of the resulting melt pool, the laser powder bed fusion process parameters can be optimized to obtain microstructures with features that improve the creep properties.
Extracellular matrix as a driver for intratumoral heterogeneity
Authors: Pally Dharma , Goutham Shyamili , Bhat Ramray 
Published: May 2022

Abstract
The architecture of an organ is built through interactions between its native cells and its connective tissue consisting of stromal cells and the extracellular matrix (ECM). Upon transformation through tumorigenesis, such interactions are disrupted and replaced by a new set of intercommunications between malignantly transformed parenchyma, an altered stromal cell population, and a remodeled ECM. In this perspective, we propose that the intratumoral heterogeneity of cancer cell phenotypes is an emergent property of such reciprocal intercommunications, both biochemical and mechanical-physical, which engender and amplify the diversity of cell behavioral traits. An attempt to assimilate such findings within a framework of phenotypic plasticity furthers our understanding of cancer progression.