bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengembangan LKPD (Lembar Kerja Peserta Didik) Berbasis AIR (Auditory Intellectualy Repitition) Pada Materi Sistem Gerak Manusia Dikelas XI MIPA SMA Negeri 1 Palopo
Authors: Khaerati  , Martipa  
Published: April 2022

This study aims to determine the results of the development of AIR (Auditory Intellectualy Repetition) based LKPD (student worksheets) on the material of the human movement system class XI MIPA Senior high school number 1 Palopo. This type of research is R&D (Research and Development) research which refers to the development research design of Hannafin and Peck (1988) which consists of three stages namely needs assessment, design stage, and implementation development stage. The results of the study show that the development of AIR (Auditory Intellectualy Repetition) based LKPD (student worksheets ) on the material of the human movement system class XI MIPA 1 Senior High School Number 1 Palopo is stated: (1) valid with an average total validity value 3,7 the percentage value of validity is 92,5% criteria very valid (2) the p ercentage of teacher responses to the AIR (Auditory Intellectualy Repetition) based LKPD (student worksheets) with an average value 3,8 with a percentage value of 95% very partical criteria (3) the percentage of student responses to the AIR (Auditory Intellectualy Repetition) based LKPD (student worksheets) with an average value of 3,32 with a percentage of 83%) partical criteria (4) the percentage value of effevtiveness of the AIR (Auditory Intellectualy Repetition) based LKPD (student worksheets) with an average value of 83,77% very effective criteria. These criteria indicate that development AIR (Auditory Intellectualy Repetition) based LKPD (student worksheets) is valid, practical, and effective.
ŞİİRDE MÜZİK, ORYANTALİZM VE YAHYA KEMAL’İN ŞİİRLERİNDEKİ GİZLİ MÜZİĞİN KİMLİĞİ
Authors: ALTIKULAÇ DEMİRDAĞ Refika 
Published: April 2022

Şiirde ritim ve ahenk unsurlarının müzikle ifade edilme çabası edebiyat tarihi boyunca şiir sanatı için vazgeçilmez bir konu kabul edilmiştir. Şairin duygularını dile getiriş biçimindeki ahenk, müzikte olduğu gibi bir takım iniş çıkışlar, imalar, sarsılmalar, yükselme ve alçalmalar, geçişler ya da genişlemeler gibi unsurların bir araya gelmesiyle bir kompozisyon oluşturur. Bunun bir ezgiye denk geldiği fikri bu çalışmanın varsayımını oluşturmaktadır. Çalışmada ezgi ya da ahengin sadece seslerle değil, anlamla da ilişkili olduğu fikri benimsenmiş, ezginin müzik gibi notalarla ifade edilebilmesi için anlama ilişkin yapıların tespit edilerek görünür kılınmasının mümkün olabileceği fikrinden hareket edilerek örnek bir uygulama denemesi yapılmıştır.
Türk şiirinde ahenk konusuna ilgi çeken önemli sanatçılardan biridir Yahya Kemal. Şair, “derunî ahenk” fikriyle şiirin sadece dış unsurlarını değil, anlamını da ahengin konusu yapar. Onun “derunî ahenk” kavramına yüklediği anlamla Rahip Bremond’un kullandığı kavram karşılaştırılmış, iki şairin tam anlamıyla örtüşen bir ahenkten bahsetmedikleri sonucuna ulaşılmıştır. Aradaki en belirgin farkın mistik duyuşla ilgili olduğu söylenebilir. Bu farklılığın Yahya Kemal’in şiirine nasıl yansıdığı üzerinde bir değerlendirme yapmak için şiirlerdeki ahengin kimliği ortaya çıkarılmaya çalışılmıştır. Yahya Kemal’in şiirindeki iç ahengin müzik notalarıyla ifade edilme şansı olsa, Kendi Gök Kubbemiz’de toplanan şiirlerdeki saklı müzik hangi tür müziğin özelliklerini gösterir, sorusunun yanıtı bulunmaya çalışılmıştır. Sanatçının şiirlerinde Batı müziği ile Türk müziği arasında bir bağ kurduğu iddia edilmiş, bu bağı Batılı bir bestekâr üslubuyla kurup kurmadığı tartışılmıştır. Şairin Batı referanslarından hareket ederek Doğu kültürüne yaklaşımının oryantalist etkiler içerip içermediği konusunda değerlendirme yapılmıştır. Bu değerlendirme sonucunda şiirlerde hissedilen anlama ilişkin nağmelerin gidiş, salınış, akış ya da dağılışının ne Türk müziğindeki makam formuyla açıklanabileceği ne de Batı müziğinin senfonik çok sesliliğine sahip olduğunun söylenebileceği sonucuna ulaşılmıştır. Şairin iki tür müzik arasında organik bir bağ kurduğu ve bu bağı Türk müziği temelinde işlediği ispatlanmaya çalışılmıştır.
STUDY OF TOXIC HEAVY METAL REMOVAL BY DIFFERENT CHITOSAN/HYACINTHS PLANT COMPOSITE
Authors: & et al. Rashid 
Published: April 2022

Water pollution with toxic heavy metals represents a most important problem, as a result of releasing these metals to ecological ambient without treatment, leading to their persistence and non-biodegradation. A variety of traditional methods are utilized as an attempt to remove heavy metals from waste water, but still without making any actual progress. In present work Eichhorniacrassipes (water hyacinth) root and shoot powder ,and ash case with chitosan are used as a removal system for heavy metals (HM), including lead, copper and cadmium from waste water via biosorption process .It was carried out by using two different experimental conditions: (i) heavy metal concentration (1000 ppm), with different pH values, ranged between 3-8 with a constant (HM) (ii) using variable (HM) concentrations with a range (250, 500, 750 and 1000 ppm). The results proved a good absorption for the hyacinths plant to the heavy metal ions especially chitosan /hyacinth shoot . Moreover, it was seen that highest removal (98%) of Pb (II), while was removed (98.2%) of Cu (II) and removed )96.8%) of Cd (II) where removal within 24 hr. On the other hand, FTIR spectra of composite materials showed only the characteristic of raw materials bands, which provided a strong indication of composite formation.
Merged testing for colorectal cancer syndromes and re‐evaluation of genetic variants improve diagnostic yield: Results from a nationwide prospective cohort
Authors: Svensson Sara , Zagoras Theofanis , Aravidis Christos , Askmalm Marie Stenmark , Björck Erik , Borg Åke , Kuchinskaya Ekaterina , Nilbert Mef , Nordling Margareta , Rohlin Anna , Silander Gustav , Lagerstedt‐Robinson Kristina , Gebre‐Medhin Samuel 
Published: April 2022

AbstractApproximately 5% of patients with colorectal cancer (CRC) have a Mendelian predisposition for the disease. Identification of the disease‐causing genetic variant enables carrier testing and tailored cancer prevention within affected families. To determine the panorama and genetic variation of Mendelian CRC syndromes among referrals at the cancer genetics clinics in Sweden, 850 patients clinically selected for CRC genetic investigation were included in a prospective study that tested for all major hereditary polyposis and nonpolyposis CRC conditions. Genetically defined syndromes were diagnosed in 11% of the patients. Lynch syndrome was predominant (n = 73) followed by familial adenomatous polyposis (n = 12) and MUTYH‐associated polyposis (n = 8); the latter of which two patients presented with CRC before polyposis was evident. One patient with a history of adolescent‐onset CRC and polyposis had biallelic disease‐causing variants diagnostic for constitutional mismatch repair deficiency syndrome. Post‐study review of detected variants of unknown clinical significance (n = 129) resulted in the reclassification of variants as likely benign (n = 59) or as diagnostic for Lynch syndrome (n = 2). Our results reveal the panorama of Mendelian CRC syndromes at the cancer genetics clinics in Sweden and show that unified testing for polyposis and nonpolyposis CRC conditions as well as regular reexamination of sequence data improve the diagnostic yield.
Simplification from tenofovir disoproxil fumarate plus lamivudine or emtricitabine plus ritonavir-boosted protease inhibitor to ritonavir-boosted atazanavir plus lamivudine in virologically suppressed HIV-infected adults with osteopenia: a pilot study
Authors: Blanco José L , Rojas Jhon , de Lazzari Elisa , Inciarte Alexy , Subirana Mar , Callau Pilar , Martinez-Rebollar María , Laguno Montserrat , Mallolas Josep , de la Mora Lorena , Torres Berta , Gonzalez-Cordón Ana , Martinez Esteban 
Published: April 2022

Abstract

Background
Tenofovir disoproxil fumarate, particularly when given with a ritonavir-boosted PI, reduces bone mineral density (BMD) and increases bone turnover markers (BTMs). Ritonavir-boosted atazanavir plus lamivudine is a feasible simplified option. We evaluated whether switching from a triple ritonavir-boosted PI plus tenofovir disoproxil fumarate to a two-drug regimen of lamivudine plus ritonavir-boosted atazanavir would improve BMD.

Methods
Single-arm pilot study. Virologically suppressed patients on tenofovir disoproxil fumarate plus lamivudine or emtricitabine plus ritonavir-boosted PI with low BMD, without previous resistance mutations and/or virological failure to study drugs were switched to 100/300 mg of ritonavir-boosted atazanavir plus 300 mg of lamivudine once daily. The primary endpoint was BMD change by DXA at Week 48.

Results
There were 31 patients, 4 (13%) female, and median age was 40 years. Seven participants (22.5%) had osteoporosis. At 48 weeks, mean (SD) changes in spine and hip BMD were +0.01 (0.03) (P = 0.0239) and +0.013 (0.03) g/cm2 (P = 0.0046), respectively. Mean (SD) T-score changes were +0.1 (0.23) (P = 0.0089) and +0.25 (0.76) (P = 0.0197), respectively. N-telopeptide and urine tenofovir disoproxil fumarate toxicity markers showed significant improvements. One participant withdrew from the study and two were lost to follow-up. There were no virological failures, or serious or grade 3–4 adverse events.

Conclusions
Switching from a tenofovir disoproxil fumarate plus ritonavir-boosted PI triple therapy to a lamivudine plus ritonavir-boosted atazanavir two-drug regimen in virologically suppressed HIV-infected adults with low BMD was safe, increased low BMD and reduced plasma markers of bone turnover and urine markers of tenofovir disoproxil fumarate toxicity over 48 weeks.
An ALS‐associated KIF5A mutant forms oligomers and aggregates and induces neuronal toxicity
Authors: Nakano Juri , Chiba Kyoko , Niwa Shinsuke 
Published: April 2022

AbstractKIF5A is a kinesin superfamily motor protein that transports various cargos in neurons. Mutations in Kif5a cause familial amyotrophic lateral sclerosis (ALS). These ALS mutations are in the intron of Kif5a and induce mis‐splicing of KIF5A mRNA, leading to splicing out of exon 27, which in human KIF5A encodes the cargo‐binding tail domain of KIF5A. Therefore, it has been suggested that ALS is caused by loss of function of KIF5A. However, the precise mechanisms regarding how mutations in KIF5A cause ALS remain unclear. Here, we show that an ALS‐associated mutant of KIF5A, KIF5A(Δexon27), is predisposed to form oligomers and aggregates in cultured mouse cell lines. Interestingly, purified KIF5A(Δexon27) oligomers showed more active movement on microtubules than wild‐type KIF5A in vitro. Purified KIF5A(∆exon27) was prone to form aggregates in vitro. Moreover, KIF5A(Δexon27)‐expressing Caenorhabditis elegans neurons showed morphological defects. These data collectively suggest that ALS‐associated mutations of KIF5A are toxic gain‐of‐function mutations rather than simple loss‐of‐function mutations.
The compliance of nutrition claims on pita bread in Lebanon and risk on public health: a cross-sectional study
Authors: Bedran Priscilla , Bou-Mitri Christelle , Merhi Samar , Doumit Jacqueline , Fares Jessy El Hayek , Farhat Antoine G. 
Published: April 2022

Abstract
Background
Mislabeling is a type of fraud, that can lead to major health concerns, especially when used on staple foods like bread. This study aimed to assess the compliance of nutrition claims on pre-packaged Pita bread in Mount Lebanon with national (LIBNOR; NL 661:2017) and international (CODEX; CAC/GL -2–1985) standards.

Methods
A cross-sectional study was conducted and Lebanese bread samples (n = 75) were collected from all the registered bakeries in Mount Lebanon directorate (n = 25). The claim compliance assessment was based on values of the nutrition facts panel and standard nutrient analyses, following official methods.

Results
Of all assessed breads, 84% carried nutrition claims, and 25.3% carried health claims. Among nutrition claims, 70.7% had non-addition claims, 56.0% had nutrient content claims, and 1.3% had comparative claims. The results showed a high prevalence of nutrition claims with majority non-compliant. Based on the nutrition facts panel, only 32.4% of the sugar related claims, 45.5% of the fiber claims, and 54.4% of salt claims were eligible to make those statements. Based on the chemical nutrient analyses, only 47.0% of sugar claims, 16.1% of fiber claims, and 37.5% of salt claims were compliant. All the claims related to protein (n = 7) were compliant.

Conclusions
These results suggest the urgent need to develop clear guidelines for the effective implementation of the current standard; in order to prevent mislead consumers from making poor decisions at the point-of-sale, which might affect their overall health and efforts towards proper nutrition.
Angiographic analysis on posterior fossa hemorrhages and vascular malformations beyond aneurysms by CT angiography and digital subtraction angiography
Authors: Vignesh S. , Prasad Surya Nandan , Singh Vivek , Neyaz Zafar , Phadke R. V. , Mehrotra Anant , Mishra Prabhakar 
Published: April 2022

Abstract
Background
Posterior fossa malformations are less common than supratentorial malformations, but hemorrhages in posterior fossa are more serious due to presence of vital structures within this region. Most common cause of bleed in posterior fossa apart from hypertension is aneurysms but other vascular malformations are also there which cause hemorrhage. Here we discuss other causes of posterior fossa bleed beyond aneurysms.

Results
A total of 80 patients were evaluated: 47 (58.8%) had aneurysms, 29 (36.3%) had arteriovenous malformations, one each had developmental venous anomaly and brainstem cavernoma. Thirty vascular malformations were detected, of which 18 (62.1%) were pial arteriovenous malformations (AVMs), 11 (37.9%) were dural arteriovenous fistulas (dAVF), and one had developmental venous anomaly (DVA). Six patients of AVM underwent both DSA and CTA, and CTA could correctly diagnose only 2 of 4 pial AVMs detected by DSA. Among two dAVFs detected by DSA, CTA could demonstrate dAVF only in one patient.

Conclusion
CTA could be used as alternative to DSA in diagnosis and characterizing aneurysms in posterior fossa but for AVMs, 3D-CTA cannot replace DSA; however potential of time-resolved CTA (TR-CTA) appears promising.
Acting across Borders: Mobility and Identity in Italian Cinema, Alberto Zambenedetti (2021)
Authors: Leavitt IV Charles L. 
Published: April 2022

Review of: Acting across Borders: Mobility and Identity in Italian Cinema, Alberto Zambenedetti (2021)
Edinburgh: Edinburgh University Press, 256 pp.,
ISBN 978-1-47443-986-2, h/bk, $105.00
Mario Garbuglia luce sulla scena: Ricordi di cinema e teatro, Dani Massidda (ed.) (2021)
Authors: Keating Carla Mereu 
Published: April 2022

Review of: Mario Garbuglia luce sulla scena: Ricordi di cinema e teatro, Dani Massidda (ed.) (2021)
Modena: Palombi Editori, 160 pp.,
ISBN 978-8-86060-916-8, p/bk, €15.00
The Structure of Space and its Impact on Interplanetary Travel and Answers to Fundamental Cosmological Questions
Authors: Sobolewska Natalia Julia , Sobolewska Joanna Paulina , Sobolewski Marek Juliusz , Sobolewski Michał Amadeusz , Sobolewski Dariusz Stanisław 
Published: April 2022

The article presents the far-reaching implications of the theory entitled "Theory of Space" (Sobolewski D. S., Theory of Space, 2016) (Sobolewski D. S., Theory of Space, 2017) (Sobolewski D. S., Theory of Space, 2022 - new unpublished edition) and of the publication "New Generations of Rocket Engines" (Sobolewska, Sobolewska, Sobolewski, Sobolewski, & Sobolewski, 2021). Among others, it presents the shape of curved space in E4 for selected planets of the solar system and the Sun, taking into account boundary hypersurfaces and gravitational interactions. The existence of space tunnels was analysed and the perspective of new technologies enabling interplanetary travel was outlined. Furthermore, due to the revealed structure of space, cosmological issues including the existence of other Universes and possible effects of their interactions are addressed. The constant Gdańsk was also introduced GGdańsk which, together with the introduced equation, makes it possible to determine the maximum immersion depth of an astronomical object of mass M.
INFLUENCE OF MARKET RESEARCH RESULTS ON THE ORGANOLEPTIC CHARACTERISTICS OF CONFECTIONERY GLAZES
Authors: БАРАНОВА З.А. , БАРАНОВА Е.И. 
Published: April 2022

Маркетинговые исследования вкусовых предпочтений потребителей являются необходимым условием повышения качества кондитерских глазурей. С целью получения объективной оценки важности органолептических характеристик кондитерских глазурей проведены комплексные маркетинговые исследования с применением метода hall-test и метода blind-test. Валидность исследований составила более 65%. Результаты исследований позволили установить рейтинг образцов кондитерских глазурей по количеству лидирующей позиции (с учетом сознательной и бессознательной оценки), а также выявить целевые показатели создания жировых полуфабрикатов. Опрос респондентов позволил определить средние значения важности органолептических характеристик для потребителей из разных городов. На основе комплексной оценки результатов даны рекомендации для совершенствования технологии производства заменителей масла какао, в том числе нелауринового типа, без образования транс-изомеров жирных кислот.
Marketing research of consumers' taste preferences is a necessary condition to improve the quality of confectionary glazes. In order to obtain an objective assessment of the importance of specific organoleptic characteristics of confectionery glazes a comprehensive marketing research was conducted using hall-test and blind-test methods. The validity of the study was over 65%. The results of the study allowed to establish the ranking of samples of confectionery glazes on the number of leading position (taking into account the conscious and unconscious evaluation), as well as to identify targets for the creation of fat semi-finished products. The survey of respondents using a specialized scale of constructs allowed to determine the average values of the importance of organoleptic characteristics for consumers from different cities. On the basis of complex estimation of obtained results recommendations were given for improvement of production technology of cocoa butter substitutes, including non-lauric type with minimum content of trans-isomers of fatty acids.
Territórios do agronegócio e projetos de parcerias na educação
Authors: Ruscheinsky Aloisio , Rempel Enaide Tereza 
Published: April 2022

Resumo
Este artigo resulta de pesquisa no território do agronegócio, em que se analisou a relação entre as parcerias e as práticas sociais, em particular no campo da educação. Objetivamos apreender as estratégias de construção cotidiana de consenso e de obtenção de hegemonia a partir da responsabilidade social e a presença da noção de sustentabilidade em projetos ambientais de empresa transnacional. O problema de pesquisa trata da responsabilidade social como uma ideologia, mediada pelo discurso político-pedagógico do desenvolvimento sustentável, conjugando educação, legitimidade e hegemonia. A coleta de dados se baseou em documentação e entrevistas com docentes e gestores educacionais. A pesquisa concluiu que o projeto político-pedagógico corporativo viabilizou práticas associadas à homogeneização de condições diferenciadas de vida e às formas de invisibilizar tensões e conflitos no território.
Palavras-chaves: Estado. Agronegócio. Parcerias. Educação. Hegemonia.

Abstract
This article results from research in the agribusiness territory where the relationship between partnerships and social practices was analyzed, particularly in the field of education. We aim to apprehend the strategies of daily building consensus and obtaining hegemony based on social responsibility and the presence of the notion of sustainability in corporate transnational company's environmental projects. The research problem deals with social responsibility as an ideology, mediated by the political-pedagogical discourse of sustainable development, combining education, legitimacy, and hegemony. Data collection was based on documentation and interviews with teachers and educational managers. The research concluded that the corporate political-pedagogical project made possible practices associated with the homogenization of differentiated living conditions and ways of making tensions and conflicts invisible in the territory.
Keywords: State. Agribusiness. Partnerships. Education. Hegemony.
O Neoliberalismo nos Livros Didáticos de Sociologia: A exemplificação como recurso didático
Authors: Lopes Ricardo Cortez , Capriolli Aline Bernardi 
Published: April 2022

O presente trabalho trata de um estudo da utilização do recurso da exemplificação em livros didáticos de Sociologia, de maneira a compreender parte de como o processo se desenrolou nos ditos instrumentos educativos. Por meio de uma revisão conceitual, foi determinado que o exemplo pode assumir uma polissemia, que parte desde a metonímia, da demonstração ou de um modelo comportamental, de modo que também discutimos a sua utilidade para o processo didático em um geral e em específico para a didática do ensino de Sociologia. O corpus empírico foi baseado em três livros didáticos de Sociologia para o Ensino Médio, selecionados do Programa Nacional do Livro e do Material Didático (PNLD): “Sociologia para o Ensino Médio” (2012), “Sociologia para Jovens no Século XXI” (2015) e “Sociologia Hoje” (2018). O foco do estudo foi no conceito de neoliberalismo, cujas recorrências no material foram investigadas por uma análise de conteúdo.
Palavras-chaves: Ensino de Sociologia. Livro Didático. Neoliberalismo.

Abstract
The present paper deals with a study of the use of the resource of exemplification in textbooks of Sociology, in order to understand part of how the process unfolded in the called educational instruments. Through a conceptual review, it was determined that the example can assume a polysemy, starting from metonymy, from the demonstration or from a behavioral model, so that we also discuss its usefulness for the didactic process in general and specifically for the didactics of Sociology teaching. The empirical corpus was based in three textbooks on Sociology for High School: “Sociologia para o Ensino Médio” (2012), “Sociologia para Jovens no Século XXI” (2015) and “Sociologia Hoje” (2018). The focus of the study was on the concept of neoliberalism, whose recurrences in the material were investigated by a content analysis.

Keywords: Sociology teaching. Textbook. Neoliberalism.