bluuebunny/crossref_metadata_2025_split huggingface dataset:
Financial literacy, education and risk aversion: a survey of French students
Authors: Le Fur Eric , Outreville Jean-François 
Published: August 2022

PurposeFinancial literacy is generally seen as an important factor explaining a broader set of investment behaviors. In the context of a weak financial knowledge in France, this article focuses on the particular situation of Generation Z (individuals born after 1995) and more particularly management students likely to be involved in financial decisions in the near future.Design/methodology/approachThe analysis is based on a survey conducted in the Fall of 2019, through a questionnaire distributed to 300 students enrolled in a French business school.FindingsThe results indicate that financial knowledge is poor for students who do not follow a specialized course in finance. This research also demonstrates the importance of risk behavior, showing that risk adverse students are also those with the lowest level of financial literacy.Originality/valueThis article contributes to the academic literature by focusing on students in France. It is the first study to examine Gen Z financial literacy and its implications. It raises awareness on the importance of financial education in the education curriculum.
Luxury consumption amidst the COVID-19 pandemic
Authors: Kumar Prashant 
Published: August 2022

PurposeThis study investigates shifts in luxury consumers' perceptions regarding luxury consumption, subsequent changes in the meaning of luxury and antecedents of luxury observed amidst the COVID-19 pandemic.Design/methodology/approachOverall, 145, one-to-one qualitative interviews were conducted online with luxury consumers and the data acquired was analysed using NVivo.FindingsPhygital connectedness and access-based consumption are the future of luxury for luxury consumers' well-being, social connectedness, living experience and rational and thoughtful luxury consumption. Moreover, distinct luxury symbols (e.g. conciseness towards societal connotation of luxury goods and consumption, empathy, wisdom and maturity) and transformation expectations (for the self, others in society and luxury brands) govern luxury consumption behaviour.Research limitations/implicationsThe meaning of luxury amidst the pandemic is explained along a continuum, from luxury transforming consumers' inner selves to influencing other consumers' lives to transforming society.Practical implicationsLuxury professionals should include phygital experience, sustainability, social–cultural sensitivity, empathy, symbolism, mindfulness and thoughtfulness in marketing strategies.Originality/valueNew perspectives have enriched the realm of luxury.
Scientific mapping of digital transformation strategy research studies in the Industry 4.0: a bibliometric analysis
Authors: Khoshroo Mina , Talari Mohammad 
Published: August 2022

Purpose
Today, the rapid development and expansion of advanced technologies have created many changes in society and industry and motivate businesses to use digital transformation strategy (DTS) to create significant changes in the business environment. Therefore, it is necessary to define a roadmap and a vision that will determine the steps forward in this direction. In line with this, the purpose of this study is a comprehensive review of past and present studies in this field to identify future research guidelines and gaps related to the implementation of this concept.

Design/methodology/approach
This study is a bibliometric analysis using VOSviewer software for all documents published in the Scopus database in the field of DTS from 2011 (the emergence of Industry 4.0) to 2021. It should also be noted that the data for this study have been collected and analyzed in September 2021.

Findings
The current study presents the basic bibliometric results for DTS, and it focuses on DTS performance analysis and its science mapping during the past 10 years. This study first shows the publication process, types and languages of published documents, and the most influential authors, institutions, sources and countries in terms of publishing documents and receiving citations in the field of DTS. Then, by using the VOSviewer software, it shows the bibliographic coupling of top authors, institutions, sources and countries. Finally, it reports the co-occurrence of authors’ frequently occurring keywords and the timeline of their publications.

Originality/value
The study presents the results of the first attempt to conduct a comprehensive bibliometric analysis of DTS-related documents. Its contribution lies in the fact that it has categorized the most frequently co-occurring keywords into specific clusters so that researchers will know which keywords have co-occurred with each other the most. Also, the most influential keywords in each cluster in terms of having total link strength and the number of its co-occurrence with others were identified. Finally, it became clear that the process of publishing documents over time has been concentrated on topics such as acceptance of digital culture, strategic renewal and digital transformation of business models, as well as presentation of a research agenda on the applications and barriers of DTS in critical situations such as COVID-19, which leads researchers to some awareness and insights for conducting new research.
The efficacy and safety of upadacitinib treatment for moderate to severe atopic dermatitis in real‐world practice in Japan
Authors: Hagino Teppei , Saeki Hidehisa , Kanda Naoko 
Published: August 2022

AbstractWe evaluated the efficacy and safety of upadacitinib, janus kinase 1 inhibitor for atopic dermatitis (AD) in real‐world practice. From September 2021 to March 2022, 31 patients with moderate‐to‐severe AD, aged ≥12 years were treated with oral upadacitinib 15 mg/day plus topical corticosteroids. Upadacitinib reduced clinical indexes compared to baseline levels: percent reduction at week 4 and 12 (median) was 73.6% and 85.6% in eczema area and severity index (EASI); 81.3% and 81.3% in AD control tool (ADCT); and 70% and 75% in peak pruritus numerical rating score (PP‐NRS), respectively. The achievement rate of EASI 75 was 51.6% and 67.7% at week 4 and 12, respectively. Upadacitinib reduced serum lactate dehydrogenase and total eosinophil count (TEC) at week 4 and 12, and thymus and activation‐regulated chemokine and immunoglobulin E at week 4, compared to baseline levels. Percent reduction of TEC was correlated with that of EASI at week 4 and 12. Baseline TEC was positively correlated with the percent reduction of EASI at week 4. Percent reduction of EASI in female patients was higher than that in male patients at week 4 and 12. Linear multivariate regression analyses revealed that high percent reduction of EASI at week 4 or 12 was associated with high baseline TEC or female gender, respectively. There were no serious treatment‐emergent adverse events. Adverse events include acne (5%), elevation of creatine phosphokinase (9.7%), herpes zoster (1%), and AD (1%). Upadacitinib plus topical corticosteroids for patients with AD in the real‐world practice was well tolerated and gave therapeutic effects comparable with those in previous clinical trials. The ADCT and PP‐NRS rapidly reduced at week 4 while EASI gradually reduced until week 12. The TEC might act both as a predictive factor of response at week 4 and as a biomarker reflecting therapeutic effects in upadacitinib treatment for AD.
Environmental filtering of macroinvertebrate traits influences ecosystem functioning in a large river floodplain
Authors: Rideout Natalie K. , Compson Zacchaeus G. , Monk Wendy A. , Bruce Meghann R. , Hajibabaei Mehrdad , Porter Teresita M. , Wright Michael T. G. , Baird Donald J. 
Published: August 2022

AbstractThe biodiversity–ecosystem function hypothesis postulates that higher biodiversity is correlated with faster ecosystem process rates and increased ecosystem stability in fluctuating environments. Exhibiting high spatiotemporal habitat diversity, floodplains are highly productive ecosystems, supporting communities that are naturally resilient and highly diverse.We examined linkages among floodplain wetland habitats, invertebrate communities and their associated traits, and ecosystem function across 60 sites within the floodplain wetlands of the lower Wolastoq | Saint John River, New Brunswick, using structural equation modelling and Threshold Indicator Taxa ANalysis.We identified key environmental filters structuring invertebrate communities, by linking increased niche differentiation through shoreline change, flood pulse dynamics, and macrophyte bed complexity with increased taxa and functional diversity.Examination of traits linked to ecosystem functions revealed that more resilient wetlands with balance between primary productivity and decomposition as carbon sources were associated with greater functional evenness and richness, while habitat patches with elevated decomposition rates had lower functional richness, reflecting a simplified, more disturbed habitat.While our more complex overarching SEM model was ultimately compromised by an overspecified number of pathways, our results nevertheless are indicative of a divergence between wetland and riverine ecosystems in their relationships linking biodiversity and ecosystem function, illustrating how to define ecosystem health in wetland habitats, and demonstrating how critical functions support healthy wetland habitats by providing increased resilience to disturbance.Read the freePlain Language Summaryfor this article on the Journal blog.
The outcome of patients with stress urinary incontinence combined with pelvic organ prolapse treated by mid‐urethral linear suspension
Authors: Tang Biao , Wang Jing , Chen Dexin , Wan Hong , Han Xu , Wang Qinjie , Zhao Zhigang , Li Ming 
Published: August 2022

AbstractObjectiveTo report the clinical outcomes of 80 patients with stress urinary incontinence combined with pelvic organ prolapse treated by linear suspension of the middle‐ part of the urethra.MethodologyRetrospective analysis of 80 patients who underwent linear suspension of the middle part of the urethra to treat stress urinary incontinence and repair of pelvic organ prolapse in our hospital from January 2010 to April 2019.ResultsThe mean age of the patients was 50.98 ± 9.7 years old, the follow‐up time was 6–109 months. 54/80 (67.5%) were cured, 11/80 (13.8%) were improved, 10/80 (12.5%) were not cured, and 5 /80 (6.3%) were relapsed. Pelvic organ prolapse quantitation (POP‐Q) scale had no effect on treatment of stress urinary incontinence.ConclusionLinear suspension of the middle part of urethra can be an alternative method to treat stress urinary incontinence combined with pelvic organ prolapse.
Encapsulation of phenolic and antioxidant compounds from spent coffee grounds using spray‐drying and freeze‐drying and characterization of dried powders
Authors: Araújo Cintia da Silva , Vimercati Wallaf Costa , Macedo Leandro Levate , Saraiva Sérgio Henriques , Teixeira Luciano José Quintão , da Costa Joyce Maria Gomes , Pimenta Carlos José 
Published: August 2022

AbstractSpent coffee grounds (SCG) are a coproduct that causes environmental impacts worldwide. Thus, consciously reusing the SCG is an eminent need. This work aimed to encapsulate phenolic compounds and antioxidants obtained from SCG extracts through spray‐ and freeze‐drying techniques using different isolated and combined wall materials. The dried powders produced were evaluated for moisture content, water activity, bulk density, hygroscopicity, color, content of phenolic compounds and antioxidants, and the results were compared. The results showed that all evaluated treatments resulted in a powdered product with low values of bulk density, moisture and water activity, especially for freeze‐drying. The freeze‐dried product also showed higher hygroscopicity. Regarding the content of phenolic compounds and antioxidants, both drying methods showed high levels of these compounds in the dried product and good encapsulation efficiency, reaching 83.43%. In most cases, spray‐drying and freeze‐drying did not differ statistically (p > 0.05) in relation to bioactive compound content and encapsulation efficiency. In relation to wall materials, albumin showed the worst performance in the retention of bioactive compounds. On the other hand, pure gum arabic combined with maltodextrin led to better preservation of these compounds.Practical ApplicationSpent coffee grounds are a coproduct generated in large quantities in the world. The encapsulation of phenolic and antioxidant compounds protects and enables their application in different food matrices. Therefore, the evaluation of different encapsulation methods and wall materials is important to define good process conditions.
Thymol and trans‐cinnamaldehyde induce apoptosis through a metacaspase‐dependent mitochondrial pathway in food‐spoilage yeast Zygosaccharomyces rouxii
Authors: Wang Huxuan , Peng Zhonghua , Wang Cong , Zhu Yanan , Xia Fei , Sun Hongmin 
Published: August 2022

AbstractThis work aimed for the first time to provide detailed insights into thymol and trans‐cinnamaldehyde's mechanisms of action on the food‐spoilage yeast Zygosaccharomyces rouxii and offers evidence in favor of the activation of an apoptosis‐like phenotype. The action mechanisms of thymol and trans‐cinnamaldehyde were investigated by the measurement of a series of typical apoptotic features using flow cytometer or microplate reader. Moreover, quantitative reverse transcription PCR (QRT‐PCR) was performed to investigate the effects of thymol and trans‐cinnamaldehyde on the transcription of key regulators of apoptosis in Z. rouxii. The results indicated that the treatment of Z. rouxii with thymol or trans‐cinnamaldehyde (minimum inhibitory and subinhibitory concentrations) triggered reactive oxygen species (ROS) accumulation, elevated intracellular Ca2+ level, and depolarized mitochondrial membrane potential (MMP) coupled with hallmarks of apoptosis including mitochondrial cytochrome c (cyt c) release, metacaspase activation, phosphatidylserine (PS) exposure, and DNA fragmentation. Moreover, thymol or trans‐cinnamaldehyde treatment upregulated the transcription of proapoptotic regulators including Yca1, Dnm1, Nuc1, Ndi1, and Mmi1 and downregulated the transcription of antiapoptotic regulators of Fis1 and Cdc48, further confirming the apoptosis induced by thymol and trans‐cinnamaldehyde in Z. rouxii. In summary, thymol and trans‐cinnamaldehyde probably induced apoptosis through a metacaspase‐dependent mitochondrial pathway in Z. roxuii. These findings provide theoretical support for the development of safe and efficient agents used in food preservation.Practical ApplicationThe results will provide a new idea for the systematic analysis of the antifungal mechanisms of thymol and trans‐cinnamaldehyde and also provide a theoretical support for the development and application of natural food preservatives, which is of positive significance for the effective control of the spoilage caused by Z. rouxii in food processing and storage and the protection of consumers’ health.
Esophageal cancer: Outcome and potential benefit of esophagectomy in elderly patients
Authors: Laurent Adeline , Marechal Raphael , Farinella Eleonora , Bouazza Fikri , Charaf Yassine , Gay France , Van Laethem Jean‐Luc , Gonsette Kimberly , El Nakadi Issam 
Published: August 2022

AbstractBackgroundThis analysis evaluated the morbimortality and the potential benefit of esophagectomy for cancer in elderly patients.MethodsPatients who underwent esophagectomy for EC were divided into elderly (≥70 years) and nonelderly (<70 years) groups. The groups were compared regarding patient and tumor characteristics, postoperative morbimortality, and disease‐free, overall and cancer‐specific survival.ResultsSixty‐one patients were classified into elderly, and 187 into nonelderly groups. The elderly were characterized by a higher rate of WHO score (p < 0.0001), higher cardiac (p < 0.004) and renal (p < 0.023) comorbidities.The rate of neoadjuvant therapy and especially of neoadjuvant CRT was significantly lower in elderly patients (p < 0.018 and p < 0.007). Operative morbidity was also higher in this group (p < 0.024).The 30‐ and 90‐day mortality was 8.2 and 11.5%, respectively in elderly patients and 0.5 and 3.2% in nonelderly patients (p < 0.004 and p < 0.012). This 90‐day mortality decreased when specific surgery‐related deaths were taken into consideration. OS and DFS were significantly better in the nonelderly group (p < 0.003 and p < 0.005) while no difference was observed for cancer‐specific survival (CSS).ConclusionNo difference in CSS was observed. Although elderly patients with EC had higher postoperative morbimortality, the age should not be a criterion whether to perform, or not to perform, esophagectomy. This decision must be based on the balance between the patient's general condition and aggressive disease.
Log odds of positive lymph nodes is a robust predictor of survival and benefits from postoperative radiotherapy in stage IIIA‐N2 resected non‐small cell lung cancer
Authors: Jin Xing , Chen Donglai , Shen Yumei , Shu Jian , Sang Yonghua , Yang Wentao , Duan Shanzhou , Chen Yongbing 
Published: August 2022

AbstractBackgroundThe significance of postoperative adjuvant radiotherapy (PORT) on the survival of resected IIIA‐N2 non–small cell lung cancer (NSCLC) remains controversial. Here, we aimed to determine the predictive value of the three nodal classifications which might aid in PORT decision‐making.MethodsA total of 4797 patients with stage IIIA‐N2 resected NSCLC were identified in the Surveillance, Epidemiology and End Results (SEER) database and were grouped by whether PORT was administered. Survival analysis was used to identify the patient groups who can benefit from PORT. Multivariate analysis was performed to confirm the independent risk factors for lung cancer‐specific survival (LCSS) and overall survival (OS). A validation cohort of 1184 patients from three medical centers in China were also included.ResultsPORT was not associated with better LCSS and OS in the entire cohort after propensity score matching (PSM). However, in the subgroups of positive lymph nodes 4 (PLN4), lymph node ratio 4 (LNR4), and log odds of positive lymph nodes 4 (LODDS4), PORT exhibited its role in improving LCSS (p < 0.05). Although the three nodal classifications were all identified as independent predictors of LCSS and OS, LODDS classification had the best discriminatory ability and prognostic accuracy for stage IIIA‐N2 patients. Similar results were also obtained in the validation cohort.ConclusionsThe LODDS classification not only exhibited the best prognostic performance in predicting LCSS and OS in stage IIIA‐N2 disease, but also could help tailor individualized PORT.
Risk Management in Small‐ and Medium‐Sized Businesses and How Accountants Contribute*
Authors: Moschella Jason , Boulianne Emilio , Magnan Michel 
Published: August 2022

ABSTRACTWe investigate how owners of small‐ and medium‐sized enterprises (SMEs) perceive, make sense of, and practice risk management. Drawing on Schatzki's practice theory, we theorize on how and why risk management happens in SMEs. Thus, we fill a gap in the extant literature, which focuses almost exclusively on risk management within large organizations. We interview entrepreneurs and conduct site observations to gain insight into their risk management activities, the drivers that lead to the adoption of said activities, their attitudes toward risk management, and how their accountants may shape and contribute to risk management in SMEs. We find that rather than a specific set of formal processes, entrepreneurs view risk management as a mindset that emphasizes the preservation of key assets, creation of competitive advantages, and development of local talent and expertise. We observe practices that are mainly informal yet planned, deliberate, and fully integrated within the fabric of organizations that align with ideal forms of risk management. We also find that full‐time, in‐house accountants do help entrepreneurs with risk management, while external accountants, whose main activities relate to financial statement preparation and tax filings, do not systematically help entrepreneurs manage risk. We contribute to both the theory and practice of risk management by sharing empirical insights into how SME owners perceive, make sense of, and manage risk.
Causal inference for planning randomised critical care trials: Protocol for a scoping review
Authors: Kaas‐Hansen Benjamin Skov , Granholm Anders , Anthon Carl Thomas , Kjær Maj‐Brit Nørregaard , Sivapalan Praleene , Maagaard Mathias , Schjørring Olav Lilleholt , Fagerberg Steen Kåre , Ellekjær Karen Louise , Mølgaard Jesper , Ekstrøm Claus Thorn , Møller Morten Hylander , Perner Anders 
Published: August 2022

AbstractBackgroundRandomised clinical trials in critical care are prone to inconclusiveness owing, in part, to undue optimism about effect sizes and suboptimal accounting for heterogeneous treatment effects. Planned predictive enrichment based on secondary critical care data (often very rich with respect to both data types and temporal granularity) and causal inference methods may help overcome these challenges, but no overview exists about their use to this end.MethodsWe will conduct a scoping review to assess the extent and nature of the use of causal inference from secondary data for planned predictive enrichment of randomised clinical trials in critical care. We will systematically search 10 general and specialty journals for reports published on or after 1 January 2018, of randomised clinical trials enrolling adult critically ill patients. We will collect trial metadata (e.g., recruitment period and phase) and, when available, information pertaining to the focus of the review (predictive enrichment based on causal inference estimates from secondary data): causal inference methods, estimation techniques and software used; types of patient populations; data provenance, types and models; and the availability of the data (public or not). The results will be reported in a descriptive manner.DiscussionThe outlined scoping review aims to assess the use of causal inference methods and secondary data for planned predictive enrichment in randomised critical care trials. This will help guide methodological improvements to increase the utility, and facilitate the use, of causal inference estimates when planning such trials in the future.