bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dopaminergic innervation at the central nucleus of the amygdala reveals distinct topographically and functionally segregated regions
Authors: Casey Eric , Avale María Elena , Kravitz Alexxai , Rubinstein Marcelo 
Published: October 2022

Abstract
The central nucleus of the amygdala (CeA) is involved in the expression of fear and anxiety disorders. Anatomically, it is divided in a medial, lateral (CeL), and capsular (CeC) divisions. The CeA is densely innervated by dopaminergic projections that originate in the ventral periaqueductal gray/dorsal raphe (vPAG/DR) and the ventral tegmental area/substantia nigra compacta (VTA/SNc). However, whether dopamine (DA) exerts a homogenous control over the CeA or differentially regulates the various CeA subdivisions is still unknown. Here, we performed a neuroanatomical and functional analysis of the mouse CeA and found that DAergic innervations from the PAG/DR and VTA/SNc constitute distinct, non-overlapping, pathways differing also in the relative expression of the dopamine transporter. By quantifying the distribution of DAergic fibers and the origin of DA inputs we identified two distinct regions in the CeL: a frontal region innervated by the VTA/SNc and vPAG/DR, a caudal region innervated only by the vPAG/DR and, three distinct regions in the CeC: fronto-dorsal innervated only by the VTA/SNc, fronto-ventral with sparse DAergic innervation, and a caudal region with low innervation from the vPAG/DR. In addition, we found that each region displays a unique pattern of c-Fos activation following the administration of cocaine, SKF 38393, quinpirole or haloperidol; demonstrating that all these regions are functionally distinct. In summary, we revealed unique properties of the DAergic pathways innervating the CeA, distinguishing six topographically segregated and functionally distinct regions. This unanticipated level of functional heterogeneity calls for more precise anatomical specificity in future functional studies of the CeA.
Cultural Background Differences of International Students Relating to Time Management
Authors: Kasirye Faiswal 
Published: October 2022

Abstract
Poor time management is increasing among students by the day, yet it is an essential factor that helps people from all walks of life become professionals, trustworthy, and reliable in what they do. This study aims to examine the cultural background differences of international students related to time management. In addition, this study aims to determine the differences between gender, age, and nationality in time management among international students at IIUM. This study utilizes the ABC time management model to explain the differences between the study's variables. A quantitative research design using a survey method with a questionnaire as the tool for data collection was used in this research. A sample of 282 international students at a public university participated in the study chosen through simple random sampling. The study findings reveal that students have high levels of time management. The study further reveals no statistically significant differences between male and female international students, their age groups, and their nationalities in time management. Additionally, international students noted that they regard time management highly because they are always in charge of how their time is used, prioritize essential tasks, meet required deadlines, complete tasks before they are due, do their tasks according to planned schedules, prepare daily or weekly to-do lists and concentrate on doing essential tasks. Therefore, the ABC model of time management is supported in this study.
Grassroots autonomous organizations embedding, non-agricultural employment and farmer homestead withdrawal behavior：Based on the research data of Qionglai City, Sichuan Province, China
Authors: Liu Xinyi , Xu YingXin , Y.Gao  , Zhao Kai 
Published: October 2022

Abstract
In the context of the rapid rise of the village revitalization in China,the paper examines the impact of the embedding level of grassroots autonomous organizations and farmer non-agriculture employment on the farmer homestead exit behavior. Based on the Embeddedness theory and 421 household survey in Qionglai, this study suggests that, (1) the embedding of grassroots autonomous organizations is beneficial for the farmer homestead exit behavior, but different embedding methods have different effects on farmers' homestead exit behavior. (2) The farmer non-agriculture employment can promote their homestead exit behavior, and the "U" -shaped influence relationship between the non-agricultural employment distance and the farmer homestead exit behavior appears. (3) this study confirms that the level of non-agricultural employment plays an inhibitory role in the positive influence of grassroots organizations to mobilize farmers to exit homestead. (4) Further mechanism analysis show that the moderating effect of farmer non-agriculture employment and the farmer homestead exit behavior. Therefore, it is suggested that when mobilizing farmers to voluntarily withdraw from the homestead, grass-roots organizations should actively improve their own embedding level, improve the construction of farmers 'social network and accelerate the accumulation of farmers' material capital.
A Retrospective Cohort Study of Risk of Seizures in Pre and Postoperative treatment of Supratentorial Meningioma
Authors: Rajab Yasmeen Saeed , Aji Aman Omar , Abdin Ahmad Jehad , Alkharrat Leen 
Published: October 2022

Abstract
Aim and background:
Since meningioma is the most common intracranial tumor, seizures in these patients account for a huge portion of the tumor-related epilepsy. Tumor-related seizures adversely affect the quality of life, hence a better understanding of meningioma seizure rates, associated risk factors, and potential mechanisms is critical to the development of improved treatment strategies.
Methods:
This study was conducted on 100 patients in Damascus Hospital who were diagnosed with supratentorial meningioma and were treated surgically between 2017-2021.
Results:
The incidence of preoperative seizure was found to be 0.92 higher for individuals with cerebral edema (OR =3.329) than for individuals without cerebral edema. Also, it was found that patients with cerebral edema had a higher incidence of postoperative seizures (OR =2.124) compared to patients without cerebral edema by 0.75. In addition, the incidence of seizures for people who have a tumor size of less than 4 cm is 0.23 higher than the incidence of seizures for people who have a tumor size of more than 4 cm. Lastly, the incidence of preoperative seizures for people with neurological deficits (OR =1.049) is 0.02 higher than in people without neurological deficiency.
Conclusion:
It was found that 43% cases of pre-operative seizures have occurred, and this percentage decreased to 25% in post-operative cases. A correlation between tumor classification and the incidence of preoperative seizures was observed where 66.7% of individuals with grade II meningioma had preoperative seizures, and 75% of people with grade III meningioma had preoperative seizures.
Tensor product of finite dimensional nilpotent evolution algebras
Authors: izzat  
Published: October 2022

Abstract
This paper investigates the tensor product of a finite-dimensional nilpotent evolution algebra. Some properties that translate from tensor products to factors and vice versa have been investigated, including the index of nilpotency and annihilator. The index of nilpotency of the tensor product of two nilpotent evolution algebras with different indexes of nilpotency is determined. Moreover, we investigate the tensorially decomposable of the 4-dimensional nilpotent evolution algebra. In addition, the decomposable nilpotent evolution algebra with the maximal nilindex of nilpotency has been carried out.
Quantitatively mapping local quality at super-resolution scale by rolling Fourier ring correlation
Authors: Chen Liangyi , Zhao Weisong , Huang Xiaoshuai , Qiu Guohua , Yang Jianyu , Qu Liying , Han Zhenqian , Li Xiangyu , Zhao Yue , Zhao Shiqun , Li Liuju , Luo Ziying , Wang Xinwei , Shang Guanyu , Hao Huijie , Jiu Yaming , Mao Heng , Ding XUMIN , Tan Jiubin , Liu Jian , Hu Ying , Pan Leiting , Li Haoyu 
Published: October 2022

Abstract
In fluorescence microscopy, computational algorithms have been developed to suppress noise, enhance contrast, and even enable super-resolution (SR). The local quality of the images may vary on multiple scales and these differences can lead to misconceptions. However, current mapping methods fail to finely estimate the local quality, challenging to associate the SR scale content. Here, we develop a rolling Fourier ring correlation (rFRC) to quantify reconstruction quality down to the SR scale. To visually pinpoint regions with low reliability, we combine a filtered rFRC with a modified resolution scaled error map (RSM), providing a comprehensive and concise map for further examination. We demonstrate their performances on different SR imaging modalities, and the resulting quantitative maps enable better SR images integrated from different reconstructions. Beyond that, as a model-independent assessment, we show its applications in evaluating the local restoration qualities for the deep-learning methods.
Patient Satisfaction and Oral Health-related Quality of Life (ohrqol) of Edentulous People after Mandibular Denture Relining With a Soft-liner Material: A Pilot Study
Authors: Khazaleh Mosab , Dever Garth , Taylor Jane , Ramamurthy Poornima , Sharma Dileep 
Published: October 2022

Background:
Oral health-related quality of life indicators have been effectively used to assess the influence of a range of dental treatments and interventions on patient satisfaction and acceptance.

Objectives:
The purpose of this study was to evaluate the impact of the relining of mandibular dentures with a soft-liner material, using the Oral Health Assessment Index (OHIP-14).

Methods:
Forty-two full denture wearers were selected from patients who attended 9 private prosthetic clinics in New South Wales, Australia. All participants had their lower dentures relined with a soft-liner material, according to the manufacturer’s instructions. Oral health-related quality of life was evaluated before and 1 month after relining using the Oral Health Assessment Index questionnaire. A simple descriptive quantitative analysis of the survey results was undertaken, including a comparison of median scores using the Wilcoxon paired test and binomial probability test.

Results:
In all the outcome variables measured, there was a noticeable positive effect from the denture relining. Specifically, mandibular denture relining with a silicon-based soft-liner material has a positive impact on patient satisfaction and oral health-related quality of life (OHRQoL) of edentulous patients.

Conclusion:
Patient satisfaction and oral health-related quality of life (OHRQoL) of edentulous patients can be significantly improved by the use of soft-liner materials.
Pain Management During Labor and Delivery in a Patient with Possible Local Anesthetic Resistance: A Case Report
Authors: Aliakseyeva Aksana , Villarreal Dante , Pawlowicz Natalia 
Published: October 2022

Background:
Local anesthetic resistance is a clinical entity characterized by inadequate analgesia despite technically well-performed procedures. The exact etiology and pathogenesis of this condition are not yet fully understood.

Case Presentation:
A 36-year-old Caucasian female presented to labor and delivery for induction of labor. On admission, the patient reported failure of epidural anesthesia during the previous delivery. An epidural catheter was placed, and analgesia was reported only at high doses of local anesthetic. The patient’s maximum pain level during delivery never reached a score of 2 out of 10.

Conclusion:
The most common causes of regional anesthetic failure are technical or placement failure, failure related to the local anesthetic itself, or localized infection. This patient appeared to have a true local anesthetic resistance, which was overcome by doubling the customary concentration of local anesthetic. Atypical responses to local anesthetics observed in the patient may be due to incomplete penetrance mutations in sodium channels since local anesthetics work through blocking nerve conduction by acting on these channels.
Speaking anxiety during English oral presentations
Authors: Alharbi Ayed T. 
Published: October 2022

Students at the tertiary level must be placed in an interactive learning setting since traditional lectures are no longer the most effective method of getting students involved in active learning. One of the criteria for passing the course in the department of English and Translation at Qassim University is the performance in the oral presentation simulation. Since this performance of a presentation is not just dependent on the cognitive domain but also the affective dimension, and speaking anxiety can be detrimental to students’ performance affecting their learning motivation in the long run and grades in the short term. This study, therefore, examines the level of anxiety, signs of anxiety and factors that lead to oral anxiety among Saudi EFL students. Fifty students from the department of English and Translation at Qassim University’s second semester comprised the study sample. Direct observation, in-depth interviews, and surveys were used to collect data from the participants. Results show that students experience moderate levels of anxiety related to language (M= 3.51, SD= 0.54).
Use of Artificial Intelligence in the Search for New Information Through Routine Laboratory Tests: Systematic Review
Authors: Cardozo Glauco , Tirloni Salvador Francisco , Pereira Moro Antônio Renato , Marques Jefferson Luiz Brum 
Published: October 2022

Background
In recent decades, the use of artificial intelligence has been widely explored in health care. Similarly, the amount of data generated in the most varied medical processes has practically doubled every year, requiring new methods of analysis and treatment of these data. Mainly aimed at aiding in the diagnosis and prevention of diseases, this precision medicine has shown great potential in different medical disciplines. Laboratory tests, for example, almost always present their results separately as individual values. However, physicians need to analyze a set of results to propose a supposed diagnosis, which leads us to think that sets of laboratory tests may contain more information than those presented separately for each result. In this way, the processes of medical laboratories can be strongly affected by these techniques.

Objective
In this sense, we sought to identify scientific research that used laboratory tests and machine learning techniques to predict hidden information and diagnose diseases.

Methods
The methodology adopted used the population, intervention, comparison, and outcomes principle, searching the main engineering and health sciences databases. The search terms were defined based on the list of terms used in the Medical Subject Heading database. Data from this study were presented descriptively and followed the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses; 2020) statement flow diagram and the National Institutes of Health tool for quality assessment of articles. During the analysis, the inclusion and exclusion criteria were independently applied by 2 authors, with a third author being consulted in cases of disagreement.

Results
Following the defined requirements, 40 studies presenting good quality in the analysis process were selected and evaluated. We found that, in recent years, there has been a significant increase in the number of works that have used this methodology, mainly because of COVID-19. In general, the studies used machine learning classification models to predict new information, and the most used parameters were data from routine laboratory tests such as the complete blood count.

Conclusions
Finally, we conclude that laboratory tests, together with machine learning techniques, can predict new tests, thus helping the search for new diagnoses. This process has proved to be advantageous and innovative for medical laboratories. It is making it possible to discover hidden information and propose additional tests, reducing the number of false negatives and helping in the early discovery of unknown diseases.
Pengaruh Terapi Mindfulness untuk Menurunkan Tingkat Depresi pada Ibu Hamil Risiko Tinggi
Authors: Kristyaningrum Nathalia Nindi , Moordiningsih Moordiningsih - 
Published: October 2022

Penelitian ini bertujuan untuk mengetahui pengaruh terapi mindfulness terhadap penurunan tingkat depresi pada ibu hamil risiko tinggi. Subjek penelitian adalah empat orang ibu hamil risiko tinggi, berusia 32-39 tahun dan terindikasi mengalami depresi. Desain penelitian yang digunakan adalah desain eksperimen one group pretest-posttest design. Alat pengumpulan data yang digunakan adalah Edinburgh Postnatal Depression Scale (EPDS), wawancara sebelum dan sesudah pemberian terapi, dan observasi sebelum, saat, serta sesudah pemberian terapi. Analisis data yang digunakan adalah uji Friedman Test statistik nonparametrik untuk melihat perbedaan skor pre-test, post-test, dan follow up pada kelompok eksperimen. Hasil analisis menunjukkan bahwa skor chi square sebesar 8,000 (p <0,05). Artinya bahwa terdapat perbedaan tingkat depresi antara skor pre-test, post-test, dan follow up. Partisipan penelitian pada kelompok eksperimen mengalami penurunan tingkat depresi setelah mendapatkan terapi mindfulness. Hal ini membuktikan bahwa terapi mindfulness berpengaruh terhadap penurunan tingkat depresi pada ibu hamil yang beresiko tinggi.
Media Buku Pintar Meningkatkan Hasil Belajar Keterampilan Dasar Siswa Kelas I Sekolah Dasar
Authors: Mariantini Luh , Wibawa I Made Citra , Suarjana I Made 
Published: October 2022

Banyak siswa yang kesulitan dalam meningkatkan keterampilan dasar. Tujuan penelitian ini yaitu mengembangkan Media Smart Book dalam Meningkatkan Hasil Belajar Keterampilan Dasar Siswa Kelas I SD. Jenis penelitian ini yaitu pengembangan dengan model ADDIE. Subjek uji coba yaitu 2 ahli media dan 2 ahli materi. Subjek uji coba yaitu 1 praktisi dan siswa kelas I SD yang berjumlah 28 siswa. Metode yang digunakan yaitu dengan teknik wawancara dan observasi. Instrumen pengumpulan data yang digunakan yaitu kuesioner. Teknik analisis data yaitu analisis kualitatif dan kuantitatif serta statistic inferensial. Hasil penelitian yaitu hasil penilaian oleh ahli isi media yaitu0,93 (validitas tinggi), dan ahli media mendapatkan nilai 0,87 (validitas tinggi). Skor validasi dari masing-masing responden yaitu 4,45 (sangat baik), dan 4,89 (sangat baik) hasil dari respons siswa. Dari hasil analisis disimpulkan bahwa media Smart Book layak atau valid digunakan dalam proses pembelajaran. Hasil uji-t yaitu terdapat perbedaan antara nilai pretest dan post test siswa kelas 1 sebelum dan sesudah menggunakan media Smart Book. Disimpulkan bahwa Media Smart Book dapat meningkatkan keterampilan dasar pada siswa kelas I SD. Implikasi penelitian ini smart book dapat digunakan.
Peran Orang Tua Dalam Meningkatkan Motivasi Belajar Siswa Di Masa Pandemi Covid-19
Authors: Nengsih Marliza Septia , Dafit Febrina 
Published: October 2022

Pada masa pandemi covid-19 peran orang tua diperlukan dalam proses pembelajaran jarak jauh. Orang tua dapat memberikan motivasi, perhatian dan juga dukungan untuk anak saat aktivitas belajar. Penelitian ini bertujuan untuk menganalisis peran orangtua dalam belajar siswa dan menganalisis apa saja faktor penghambat peran orangtua dalam belajar siswa. jenis penelitian ini yaitu kualitatif. Jenis penelitian ini yaitu penelitian deskriptif kualitatif. Pendekatan yang digunakan dalam penelitian ini adalah pendekatan kualitatif. Metode yang digunakan untuk mengumpulkan data yaitu wawancara, observasi dan dokumentasi. Instrument pengumpulan data penelitian ini adalah pedoman wawancara. Teknik yang digunakan dalam menganalis data yaitu analisis deskriptif kualitatif. Hasil penelitian menunjukkan bahwa peran orang tua dalam memotivasi belajar tampak dari peran sebagai pembimbing, fasilitator dan motivator. Orangtua sebagai fasilitator dengan menyediakan sarana alat belajar seperti tempat belajar, buku-buku pelajaran dan alat-alat tulis dan memberikan fasilitas untuk mengembangkan bakat dan minat anak. Orangtua sebagai motivator dengan memberikan motivasi kepada anak dengan cara memberi penghargaan terhadap prestasi belajar anak dengan memberi hadiah maupun kata-kata pujian. Orangtua sebagai pembimbing dengan terlibat dalam kegiatan belajar dengan mendiskusikan dengan pihak homeschooling mengenai program belajar yang sesuai dengan kondisi anak.
Menstimulasi Perilaku Sopan Santun Pada Anak Usia Dini Melalui Media Permainan Ular Tangga
Authors: Savitri I Gusti Ayu Putu , Tegeh I Made , Asril Nice Maylani 
Published: October 2022

Kurangnya perkembangan moral pada anak menyebabkan rendahnya perilaku sopan santun pada anak usia dini. Masih ada siswa yang kurang sopan saat mengikuti pembelajaran di kelas. Hal ini disebabkan guru kurang menstimulasi perkembangan moral pada anak. Penelitian ini bertujuan untuk menciptakan media permainan ular tangga perilaku untuk menstimulasi perilaku sopan santun pada anak usia dini. Jenis penelitian ini yaitu penelitian pengembangan dengan model ADDIE, namun pengembangan ini hanya sampai pada tahap pengembangan (development). Subjek penelitian terdiri atas 1 orang ahli media dan 1 orang ahli materi pembelajaran. Metode yang digunakan untuk mengumpulkan data yaitu observasi, wawancara dan kuisioner. Instrument yang digunakan untuk mengumpulkan data yaitu kuesioner. Analisis data dilaksanakan melalui analisis kualitatif dan kuantitatif. Hasil penelitian yaitu nilai rata-rata CVR yakni 1.00 dan CVI 1.00 dengan kriteria sangat tinggi. Dapat disimpulkan bahwa media permainan ular tangga perilaku yang dikembangkan valid dan layak digunakan pada pembelajaran. Implikasi penelitian ini yaitu guru dapat menggunakan media permainan ular tangga perilaku untuk menstimulasi perilaku sopan santun pada anak usia dini dalam pembelajaran.
Analyzing Online Marketing for Contemporary Snacks Through Instagram using SIR Model
Authors: Mohd Hilmi Nur Syazwani Atikah , Sharif Noorzila 
Published: October 2022

During the implementation of the Movement Control Order (MCO), e-marketing became a favourable solution for sellers to interact with customers at home. Today, even though the MCO is no longer in existence, online shopping behaviours have become a new norm because of a long-term impact on the interactions between seller and buyer. Since the number of online marketing is growing, sellers must understand the concept of viral marketing that suits their products. This study analyses the virality of contemporary snack marketing on the Instagram platform using the Susceptible-Infected-Recovery (SIR) model. It is essential for sellers or marketers who want to see how users react to various types of posting. It also makes it easier for customers to get the information from the postings. The parameters used in this model are the number of followers, number of reached users, and number of homepage visits. Data are collected from 14 July 2021 until 11 October 2021 at an Instagram account that promotes a type of chocolate-in-jar snack. There are three types of posting that the admin of the Instagram account frequently uses to gain customer interaction, which are Feed, Reels, and Stories. The most viral posting from each type is observed. The results reveal among the viral posts, Reels recorded the highest virality Â posted on 11 September 2021 (Saturday).