bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence and Risk Factors of Spondyloarthritis Symptoms in a US-Based Multicenter Cohort of Patients With Inflammatory Bowel Disease
Authors: Hong Simon J. , Dalal Rahul S. , Kuhn Kristine A. , Stahly Andrew , Scott Frank I. , Click Benjamin H. , Way Anna , Malik Fardina , Davis John M. , Shmais Manar , Raffals Laura E , Silfen Alexa , Rubin David T. , Dharia Ishaan , Bhattacharya Abhik , Moghaddam Bahar , Mains Trayton , Kurland Jayde , Patel Sheena , Weisman Michael H. , Ermann Joerg , Jan Reem 
Published: January 2025

INTRODUCTION:
Spondyloarthritis (SpA), the most common extraintestinal manifestation of inflammatory bowel disease (IBD), is reported in up to 39% of patients with IBD. Despite this high prevalence, risk factors of developing SpA in patients with IBD are not well described. In this study, we aimed to determine the factors associated with SpA symptoms and their prevalence in an IBD cohort.

METHODS:
Two validated screening questionnaires for the detection of SpA in IBD (DETAIL = DETection of Arthritis in Inflammatory boweL diseases, IBIS-Q = IBD Identification of Spondyloarthritis Questionnaire) were administered to patients with IBD without a prior diagnosis of SpA in 6 US academic medical centers. Demographic data, IBD characteristics, and medication history were recorded.

RESULTS:
Screening questionnaires were completed by 588 patients (220 ulcerative colitis, 349 Crohn's disease, and 19 IBD-unclassified), with a median age of 40 years (interquartile range 30–53) and median disease duration of 12 years (interquartile range 6–22). The number of positive screens was 130 (22%) for DETAIL, 196 (33%) for IBIS-Q, and 204 (35%) for either DETAIL or IBIS-Q. Age, female sex, history of smoking, prior bowel surgery, and history of any biologic or targeted small molecule exposure were associated with a positive screen on univariate analysis. After multivariate analysis, female sex (odds ratio [OR] 2.03, 95% confidence interval [CI] 1.41–2.93), older age (OR 1.02, 95% CI 1.01–1.04), history of smoking (OR 1.67, 95% CI 1.04–2.69), and history of any biologic or targeted small molecule exposure (OR 2.27, 95% CI 1.34–3.84) were independently associated with positive screens. Higher number of biologic exposures was associated with higher risk of positive screens, with the highest risk seen with 3 or more exposures (OR 3.25, 95% CI 1.75–6.03).

DISCUSSION:
A substantial number of patients with IBD screen positive for SpA symptoms, indicating a potentially high burden of undiagnosed illness. Factors associated with SpA symptoms include older age, female sex, and more severe disease (based on increased number of advanced therapies or prior surgery), whereas IBD phenotype does not independently increase the risk of a positive SpA screen. Further studies are needed to confirm these findings and better characterize SpA in IBD.
Rebound in Fecal Testing, Colonoscopy Utilization, and Colorectal Neoplasia Detection During the COVID-19 Pandemic
Authors: Langevin Michael J. , Jensen Christopher D. , Marks Amy R. , Merchant Sophie A. , Badalov Jessica , Lee Jeffrey K. , Lam Angela Y. , Halm Ethan A. , Levin Theodore R. 
Published: January 2025

INTRODUCTION:
The COVID-19 pandemic reduced colorectal cancer (CRC) screening, but the rebound in testing and outcomes after the pandemic has not been widely reported. We evaluated CRC test utilization and colorectal neoplasia detection among screening eligible patients in a large health system in 2020 and 2021, compared with 2019 (prepandemic).

METHODS:
Using a retrospective cohort study design, fecal immunochemical test (FIT) and colonoscopy utilization, FIT positivity, and neoplasia detection were evaluated annually in 2019–2021 among Kaiser Permanente Northern California patients aged 50–75 years overall and by sex, age, race and ethnicity, and spoken language preference.

RESULTS:
Compared with 2019, reductions in FIT, colonoscopy, FIT positivity, and neoplasia detection in 2020 were followed by a strong rebound in 2021 and no subgroups by age and sex or minority subgroups by race and ethnicity or spoken language preference demonstrably lagged in their recovery in 2021. Among White persons and those with an Englishlanguage preference, there was a small lag in recovery to baseline levels. The overall decline in CRC testing by colonoscopy in 2020 was offset by a lesser decrease in FIT utilization in 2020, and a strong rebound in FIT utilization in 2021 helped to offset the small lag in the rebound in colonoscopies completed in 2021.

DISCUSSION:
Findings may help guide organizations looking to improve CRC screening and minimize health care disparities related to national emergencies such as pandemics. Long-term studies are needed to evaluate how pandemic-related changes in CRC screening practices will affect future CRC outcomes.
Reduced Gastric Mucosal Nerve Density in Functional Dyspepsia: Clinical Significance and Functional Correlation
Authors: Yang Yao-Chun , Tseng Ping-Huei , Chen Chieh‐Chang , Cheng Ya‐Yin , Wei Jing-Jung , Lin Cheng-Chen , Yeh Ti-Yen , Chao Chi‐Chao , Hsieh Sung‐Tsang 
Published: January 2025

INTRODUCTION:
The aim of this study was to quantitatively examine gastric mucosal nerve density (GMND) in patients with functional dyspepsia (FD) and analyzed its clinical correlation.

METHODS:
We prospectively enrolled 35 patients with FD and 16 age-matched and gender-matched healthy controls for comparison of GMND on endoscopic biopsy, scores of Gastroparesis Cardinal Symptom Index, and gastric emptying scintigraphy.

RESULTS:
Patients with FD had lower GMND than the controls in gastric antrum, body, and fundus. GMND was inversely correlated with the Gastroparesis Cardinal Symptom Index scores, but not correlated with gastric emptying scintigraphy parameters.

DISCUSSION:
GMND was reduced in FD and inversely correlated with the symptom severity.
Time-varying reproductive number estimation for practical application in structured populations
Authors: Clancey Erin , Lofgren Eric T. 
Published: January 2025

Abstract

Objectives

EpiEstim is a popular statistical framework designed to produce real-time estimates of the time-varying reproductive number,

R

t

${\mathcal{R}}_{t}$

. However, the methods in EpiEstim have not been tested in small, non-randomly mixing populations to determine if the resulting

R

̂

t

${\hat{\mathcal{R}}}_{t}$

estimates are temporally biased. Thus, we evaluate the temporal performance of EpiEstim

R

̂

t

${\hat{\mathcal{R}}}_{t}$

estimates when population structure is present, and then demonstrate how to recover temporal accuracy using an approximation with EpiEstim.

Methods
Following a real-world example of a COVID-19 outbreak in a small university town, we generate simulated case report data from a two-population mechanistic model with an explicit generation interval distribution and expression to compute true

R

t

${\mathcal{R}}_{t}$

. To quantify the temporal bias, we compare the time points when true

R

t

${\mathcal{R}}_{t}$

and estimated

R

̂

t

${\hat{\mathcal{R}}}_{t}$

from EpiEstim fall below the critical threshold of 1.

Results
When population structure is present but not accounted for

R

̂

t

${\hat{\mathcal{R}}}_{t}$

estimates from EpiEstim prematurely fall below 1. When incidence data is aggregated over weeks the estimates from EpiEstim fall below the critical threshold at a later time point than estimates from daily data, however, population structure does not further affect timing differences between aggregated and daily data. Last, we show it is possible to recover the correct timing when by using the lagging subpopulation outbreak to estimate

R

̂

t

${\hat{\mathcal{R}}}_{t}$

for the total population with EpiEstim.

Conclusions

R

t

${\mathcal{R}}_{t}$

is a key parameter used for epidemic response. Since population structure can bias

R

t

${\mathcal{R}}_{t}$

near the critical threshold of 1, EpiEstim should be prudently applied to incidence data from structured populations.
Characteristic study of intra woven green fibers for structural application
Authors: Kar Sasmita , Pattnaik Sarojrani , Sutar Mihir Kumar 
Published: January 2025

Abstract
The current study uses three engineered fibres: white flax, brown flax, and jute fibres to form plain intra-woven fabrics. The fabrics were alkali treated with a 5 % NaOH solution and mechanical, physical, and thermal tests were conducted to characterize the individual fabrics. It was observed that treated woven fabrics significantly enhanced the overall mechanical strength compared to untreated fabrics. White and brown flax interlaced fabrics increased the tensile strength by 157 % and 574 %, Young’s modulus by 36 % and 26 %, and breaking strain by 58 % and 89 % than jute interlaced brown and white flax, respectively. Thermo-gravimetric analysis revealed that the fabric containing white flax fibre exhibited a maximum degradation temperature of 364.45 °C and after treatment, each fabric revealed a higher degradation temperature. The change in chemical composition of the green fibres after treatment was studied through Fourier transform infrared spectroscopy analysis.
Localized exciton emission from monolayer WS2 nanoribbon at cryogenic temperature
Authors: Qiang Gang , Saunders Ashley P. , Trinh Cong T. , Liu Na , Jones Andrew C. , Liu Fang , Htoon Han 
Published: January 2025

Abstract
We conducted low-temperature photoluminescence (PL) spectroscopy experiments on individual WS2 and MoSe2 nanoribbons prepared by gold-assisted exfoliation from the slanted surface of bulk crystals with a vicinal and stepwise pattern. The nanoribbons are predominantly monolayer and have widths varying from hundreds of nanometers down to tens of nanometers. Most MoSe2 NRs display an emission profile similar to 2D excitons of MoSe2 monolayers. In contrast, WS2 nanoribbons are characterized with sharp emission peaks that can be attributed to the emission from localized excitons or trions. Moreover a broad low energy emission peak can be also observed from some of the WS2 nanoribbons, which originates from bilayer regions. In this manuscript, we analyze spectral diffusion behavior along with pump power and temperature dependence of the localized exciton emission peaks, shedding light on potential of TMDC nanoribbons in sensing and opto-electronic applications.
Dinamika Abrasi terkait Perubahan Garis Pantai di Desa Pantai Bahagia Kabupaten Bekasi
Authors: Nur Elmanda Nisrina , Ananto Aji  , Heri Tjahjono  , Fahrudin Hanafi  
Published: January 2025

Desa Pantai Bahagia merupakan salah satu pesisir di Kabupaten Bekasi tepatnya di Kecamatan Muaragembong yang telah mengalami abrasi dengan sangat signifikan. Kejadian abrasi ini disebabkan oleh naiknya permukaan air laut dan adanya faktor pemicu berupa konversi lahan kawasan mangrove oleh masyarakat untuk keperluan pertambahan lahan tambak. Tujuan dari penelitian ini adalah menganalisis dinamika abrasi secara multitemporal selama 30 tahun di Desa Pantai Bahagia dari tahun 1993, 2000, 2007, 2012, 2020, 2023. Metode yang dilakukan adalah tahapan ekstraksi garis pantai dengan algoritma MNDWI (Modified Diference Water Index). Data garis pantai yang didapatkan lalu dihitung statistik dengan bantuan tools extension DSAS (Digital Shoreline Analysis System) pada ArcMap 10.8 untuk pengolahan data luas perubahan garis pantai yang memiliki nilai abrasi. Statistik yang digunakan yaitu EPR (End Point Rate) dengan membandingkan dua garis pantai serta LRR (Linear Regression Rate). Hasil yang dilakukan uji ground check di area garis pantai pada transek yang mengalami abrasi meningkat setiap tahunnya menyebabkan pengurangan daratan menjadi laut di Dukuh Muara Bendera Timur, Gobah Timur, Kampung Beting dan Blukbuk Timur. Rata –rata pengurangan daratan yang terjadi sebesar -18,77m/tahun pada 1992-2000, di tahun 2000-2007 terjadi sebesar -16,19 m/tahun, pada tahun 2007-2012 terjadi sebesar -31,86 m/tahun, pada tahun 2012-2020 memiliki rata-rata pengurangan daratan sebesar -130,13 m/tahun, serta di tahun 2020-2023 terjadi pengurangan daratan sebesar -60,32 m/tahun.
Examining the Relationship Between Fear of Childbirth During Pregnancy and Prenatal Attachment
Authors: Sari Tuğba , Gürhan Nermin 
Published: January 2025

OBJECTIVE:Giving birth is one of the most stressful events in many women's lives. Fear of childbirth is common among pregnant women, also it becomes a serious issue if it affects daily life. Psychological problems such as fear of birth in pregnancy negatively affect prenatal bonding. The aim of this study is to investigate the relationship between fear of birth and prenatal attachment in pregnancy and examine the risk factors.METHODS:The sample of the study consisted of 500 pregnant women at 20 and above weeks of gestation. Descriptive statistics (percentage, mean, standard deviation), independent groups t test, One Way ANOVA, Pearson correlation and multiple linear regression analyzes were used to evaluate the research data.RESULTS:It was found that the mean score of the pregnant women from the Wijma delivery expectancy/experience questionnaire version A scale was 58.93±21.21 and the mean score of the Prenatal Attachment scale was 52.73±8.75. As the correlation between the mean scores of the scales was examined, it was determined that there was a significant and high correlation in the negative direction.CONCLUSIONS:As a result, fear of childbirth was found to be moderate in the study and there is an inverse relationship between fear of childbirth and prenatal attachment. In addition, fear of childbirth is affected by sociodemographic factors and obstetric characteristics.
Analisis Ekolinguistik Kritis dalam Video Pandawara Group Pembersih Sampah: Perspektif Teun A. Van Dijk
Authors: Yuliastutik Rini 
Published: January 2025

This research aims to analyze critical ecolinguistics in the Pandawara Group trash cleaning video from the perspective of Teun A. Van Dijk. This research was conducted using descriptive qualitative methods with content analysis methods. The data source used is the speech of Pandawara Group members in videos on the Pandawara Group Instagram. The data collection techniques used are listening techniques and note-taking techniques. Then, the data analysis technique used consists of five stages, namely watching videos on the Pandawara Group Instagram, listening to videos, identifying (determining data), classifying data (grouping), describing (depiction of data accompanied by appropriate references). The results of this research are three data in text dimensions including, (1) Macro Structure (Thematic), (2) Superstructure (Schematic) and (3) Micro Structure (Semantic). The three data are: (1) “Believe it or not, there are still many people in the community who throw rubbish carelessly, especially into rivers”, (2) “Hey people, don’t throw rubbish carelessly, hey! Trashbarriers are broken” and (3) “Many people use this river as a place to throw away their own waste or household rubbish.”
Ekofeminisme Spritual Starhawk: Hubungan Spiritual Alam pada Novel Mantan Ledek Tayub Karya Dandang A Dahlan
Authors: Badriya Noer Lailatul , Putikadyanto Agus Purnomo Ahmad 
Published: January 2025

This research is motivated by the existence of elements of spiritual ecofeminism in the Starhawk perspective in the novel Former Ledek Tayub by Dandang A. Dahlan. The purpose of this study is to describe the form of abuse of nature carried out to oppress Ganis characters, classify the categories of spiritual ecofeminism violations experienced by Ganis characters using the Starhawk perspective, and the relationship between Ganis characters and nature. This research is a qualitative descriptive research. With data collection techniques using reading and recording techniques. The results of the research include the form of misuse of nature carried out to oppress the character of Ganis, namely witchcraft, classifying the category of violations of spiritual ecofeminism experienced by the character Ganis in the perspective of Starhawk, namely the violation of interconnection, and the relationship of the character of Ganis with nature, namely the union of Ganis with nature with meditation in tritisan that is carried out and carrying out traditions of gratitude to the Creator of nature such as ruwatan. It can be concluded that spiritual ecofeminism from the perspective of Starhawk, spiritual ecofeminism exists as a form of self-control in utilizing the surrounding nature so that this will prevent the nature of mastery and a form of awareness that humans need to be one with nature to be close to God and create peace of heart and mind.
Mapping Vulnerability Description to MITRE ATT&amp;CK Framework by LLM
Authors: Rafiey Pasha , Namadchian Amin 
Published: January 2025

Abstract

As the number and complexity of cybersecurity threats continue to increase, security professionals must augment their knowledge by utilizing resources that provide insights into the attack patterns and techniques employed by attackers. This understanding allows them to better comprehend the potential impact of a vulnerability and prioritize the development of effective mitigation strategies within their organizations. The frequent emergence of CVEs and the impracticality of manually correlating them to MITRE ATT&CK techniques necessitate the use of automated methods. Dependence on automation methods like BERT can become prohibitively expensive and time-consuming. With the continuous emergence of new vulnerabilities and revisions to the ATT&CK framework, it is necessary to retrain the model to ensure precise mapping of these evolving patterns. To address this issue, our paper leverages LLMs to automate the mapping of CVE descriptions to MITRE ATT&CK techniques, offering a scalable and accurate alternative to traditional methods. By embedding detailed CVE and MITRE ATT&CK knowledge into the LLM, the model can more precisely identify and map vulnerabilities to specific attack techniques. The paper also explores innovative prompt design methods to enhance the LLM’s comprehension and output quality. This approach using general-purpose chatbots like GPT-3.5, GPT-4 o and OpenAI o1 yields similar results with lower costs and time, providing a cost-effective solution for CVE to ATT&CK mapping.
Identification of the most dynamic river estuarine system in Bangladesh over the last fifty years (1973-2023) using Landsat Images
Authors: Sultan Niger , Mahmud Abdullah al , Tusar Kamruzzaman , Habib Muhammad Enamul , Chowdhury Sovel Ahsan 
Published: January 2025

Abstract

This study investigates the long-term trends in Bangladesh's river estuarine systems over a fifty-year period (1973–2023), with a particular focus on the dynamics of erosion and accretion across twelve significant estuaries. Using a suite of multivariate GIS techniques, including image preprocessing, mosaicking, clipping, supervised and unsupervised classification, ground truthing, and change detection, we analyzed Landsat images from 1973, 1980, 1990, 2000, 2010, and 2023, sourced from the USGS Earth Explorer. The findings reveal that over the last 50 years, a total of 1,087.56 km² of land was lost due to erosion, while 3,226.52 km² was gained through accretion, leading to a net land area increase of 2,138.95 km² in the studied estuarine systems. The Meghna River estuary emerged as the most dynamic system, with a net gain of 439.04 km², driven by substantial sediment deposition (1,041.06 km²) countered by erosion (602.02 km²). The Feni River estuary followed, exhibiting a significant net accretion of 847.85 km². The Tetulia and Banskhali River estuaries ranked third and fourth, with net increases of 595.34 km² and 281.27 km², respectively. The Bishakhali estuary ranked sixth with a net gain of 31.31 km², followed by the Balaswar, Kunga, and Sela estuaries, which saw net increases of 38.37 km², 19.92 km², and 12.19 km², respectively. Notably, the Arpangasiya estuary experienced a net loss of 9.78 km². Based on these findings, the estuarine systems were classified into three categories according to their land alteration behaviors: Highly Dynamic Systems, which include the Meghna, Feni, and Tetulia estuaries; Moderately Dynamic Systems, comprising the Banskhali, Karnaphuli, Bishakhali, Balaswar, and Kunga estuaries; and Less Dynamic or Erosion-Dominated Systems, including the Sela, Sangu, Payra, and Arpangasiya estuaries. This research underscores the importance of understanding the complex interactions that shape these ecosystems, emphasizing the need for ongoing studies to support conservation and management efforts in the context of environmental change.
Conformationally Defined Planar-Chiral [n]Paracyclophanes Stabilized by Chiral Ansa Chains
Authors: Zhao Changgui , Wang Jiaming , Wen Yilu , Lv Kang , Liu Tao 
Published: January 2025

Abstract

Although chiral substituents have been incorporated into ansa chains to stabilize the conformations of cyclophanes and modulate the biological activities of pharmaceuticals, the asymmetric syntheses of these atropisomers relies on substrate-induced diastereoselective macrocyclization. Consequently, enantio-, atrop-, and diastereoselective macrocyclizations are yet to be reported. Herein, we describe a N-heterocyclic carbene (NHC) and chiral phosphoric acid (CPA) dual-catalytic process for the desymmetrization of 1,3-diols, to achieve macrocyclization and stereoselective control over two chiral elements. It was deduced that the hydrogen bonding of CPA with the 1,3-diols enhanced the diastereoselectivity of the process. As a result, various planar-chiral cyclophanes bearing chiral ansa chains were synthesized. Thermodynamic experiments revealed that the presence of an all-carbon quaternary carbon center on the ansa chain significantly increased the rotational barriers of the cyclophanes. Moreover, density functional theory calculations suggested that the chiral substituent shrinks the ansa chain by compressing the bond angle, thereby rendering the conformational rotation reaction more challenging.
SF-DaM: An Efficient Lightweight Approach for Detecting and Mitigating the TCP SYN Flooding Attacks in SDN
Authors: Rabed Ahmed , Abdulrazzaq Fuaad , Al-Mqdashi Abdulmajid , Al-Sanabani Maher 
Published: January 2025

Abstract

Despite of its impressive advantages over the traditional networks, SoftwareDefined Networking (SDN) still encounters many challenges, especially when it comes to network security problems. The SYN flooding attacks is considered as the most effective and widely adopted DDoS mechanism to mount saturation on SDN control plane as well as on the targeted victim end systems. Although various studies have addressed this problem area, their solutions do not solve the issue efficiently due to the complexity and impracticality of their designs or due to the significant overhead and long time required for attack detection and mitigation. Therefore, in this paper, we propose an efficient lightweight security approach called SF-DaM for providing fast and accurate alleviation of the SYN flooding attacks in SDNs. The proposed SF-DaM employs a lightweight but effective mechanism for monitoring the incoming TCP connection requests and validating their legitimacy with low overhead which make it capable of detecting and blocking the sources of malicious requests quickly without sacrificing the benign host traffics. To demonstrate its feasibility and effectiveness, the SF-DaM is fully implemented as an extension module of the SDN POX controller and is evaluated under different conditional scenarios via the Mininet emulator. The experimental results illustrate the out-performance of SF-DaM when compared to the state-of-the-art approaches as it can provide a significant improvement on the attack detection time and benign response time specially under the spoofed attacks scenarios. The results also shows that SF-DaM can significantly reduce the overhead on the controller and its control channels.