bluuebunny/crossref_metadata_2025_split huggingface dataset:
Indian Ocean Dipole and ENSO’s mechanistic importance in modulating the ensuing-summer precipitation over Eastern China
Authors: Zhang Yue , Zhou Wen , Wang Xin , Chen Sheng , Chen Jiepeng , Li Shanshan 
Published: June 2022

AbstractEastern China was extremely wet in summer 2020, which is found to be related to the potential delayed effects of the Indian Ocean Dipole (IOD). Additional knowledge is warranted to improve our understanding of detailed mechanisms of such an effect. In this study, we compared physical processes associated with delayed effects of the IOD and El Niño–Southern Oscillation (ENSO) on summer precipitation. Partial correlation and composite analysis reveal that ENSO modulates precipitation mainly over the Yangtze River Valley, whereas IOD benefits precipitation farther north. Both IOD and ENSO can stimulate anticyclonic circulation over the western North Pacific (WNP) in the ensuing summer but with different spatial distributions related to the different sea surface temperature (SST) evolution processes. IOD is similarly followed by warming signals in the Indian Ocean, known as the “capacitor” effect, but the location is closer to Australia than that associated with ENSO. IOD also stimulates significant SST cooling anomalies over the equatorial Pacific during the ensuing summer, jointly contributing to the anomalous anticyclone over WNP. Numerical experiments confirm that combined effects of the Indian Ocean “capacitor” and equatorial Pacific cooling can generate an anomalous anticyclone with wider distribution in the meridional direction over WNP.
Distributed learning for heterogeneous clinical data with application to integrating COVID-19 data across 230 sites
Authors: Tong Jiayi , Luo Chongliang , Islam Md Nazmul , Sheils Natalie E. , Buresh John , Edmondson Mackenzie , Merkel Peter A. , Lautenbach Ebbing , Duan Rui , Chen Yong 
Published: June 2022

AbstractIntegrating real-world data (RWD) from several clinical sites offers great opportunities to improve estimation with a more general population compared to analyses based on a single clinical site. However, sharing patient-level data across sites is practically challenging due to concerns about maintaining patient privacy. We develop a distributed algorithm to integrate heterogeneous RWD from multiple clinical sites without sharing patient-level data. The proposed distributed conditional logistic regression (dCLR) algorithm can effectively account for between-site heterogeneity and requires only one round of communication. Our simulation study and data application with the data of 14,215 COVID-19 patients from 230 clinical sites in the UnitedHealth Group Clinical Research Database demonstrate that the proposed distributed algorithm provides an estimator that is robust to heterogeneity in event rates when efficiently integrating data from multiple clinical sites. Our algorithm is therefore a practical alternative to both meta-analysis and existing distributed algorithms for modeling heterogeneous multi-site binary outcomes.
Harmonization and standardization of data for a pan-European cohort on SARS- CoV-2 pandemic
Authors: Rinaldi Eugenia , Stellmach Caroline , Rajkumar Naveen Moses Raj , Caroccia Natascia , Dellacasa Chiara , Giannella Maddalena , Guedes Mariana , Mirandola Massimo , Scipione Gabriella , Tacconelli Evelina , Thun Sylvia 
Published: June 2022

AbstractThe European project ORCHESTRA intends to create a new pan-European cohort to rapidly advance the knowledge of the effects and treatment of COVID-19. Establishing processes that facilitate the merging of heterogeneous clusters of retrospective data was an essential challenge. In addition, data from new ORCHESTRA prospective studies have to be compatible with earlier collected information to be efficiently combined. In this article, we describe how we utilized and contributed to existing standard terminologies to create consistent semantic representation of over 2500 COVID-19-related variables taken from three ORCHESTRA studies. The goal is to enable the semantic interoperability of data within the existing project studies and to create a common basis of standardized elements available for the design of new COVID-19 studies. We also identified 743 variables that were commonly used in two of the three prospective ORCHESTRA studies and can therefore be directly combined for analysis purposes. Additionally, we actively contributed to global interoperability by submitting new concept requests to the terminology Standards Development Organizations.
Multiple magnetic orders in LaFeAs1-xPxO uncover universality of iron-pnictide superconductors
Authors: Stadel Ryan , Khalyavin Dmitry D. , Manuel Pascal , Yokoyama Koji , Lapidus Saul , Christensen Morten H. , Fernandes Rafael M. , Phelan Daniel , Chung Duck Young , Osborn Raymond , Rosenkranz Stephan , Chmaissem Omar 
Published: June 2022

AbstractThe iron-pnictide superconductors have generated tremendous excitement as the competition between magnetism and superconductivity has allowed unique in-roads towards elucidating a microscopic theory of unconventional high-temperature superconductivity. In addition to the stripe spin density wave ($${C}_{2M}^{a}$$

C

2
M

a

) phase observed in the parent compounds of all iron-pnictide superconductors, two novel magnetic orders have recently been discovered in different parent structures: an out-of-plane collinear double-Q ($${C}_{4M}^{c}$$

C

4
M

c

) structure in the hole-doped (Ca, Sr, Ba)1-x(Na)xFe2As2 and Ba1-xKxFe2As2 families, and a spin vortex crystal “hedgehog” ($${C}_{4M}^{{ab}}$$

C

4
M

a
b

) structure in the CaKFe4As4 family. Using neutron diffraction, we demonstrate that LaFeAs1-xPxO contains all three magnetic orders within a single-phase diagram as a function of substitution, all of which compete strongly with superconductivity. Our experimental observations combined with theoretical modeling demonstrate how the reduction in electronic correlations by chemical substitution results in larger Fermi surfaces and the sequential stabilization of multiple magnetic anisotropies. Our work presents a unified narrative for the competing magnetic and superconducting phases observed in various iron-pnictide systems with different crystal structures and chemistry.
Extensive performance investigation of Luo converter‐based modified firefly maximum point tracking algorithm for permanent magnet synchronous motor‐driven photovoltaic pumping system
Authors: Priyadarshi Neeraj , Maroti Pandav Kiran , Hussien Mohamed G. 
Published: June 2022

AbstractThis research paper deals the practical performance analysis of Permanent Magnet Synchronous Motor (PMSM) drives‐based photovoltaic (PV) pumping applications. A modified firefly algorithm (MFA) based maximum power point tracker (MPPT) with Luo converter is employed. In this research work, equated to classical Firefly algorithm, the degree of attractiveness (α) has been updated in each iteration number with rejection of coefficients of absorption (β) as well as random movement factor (γ) to achieve faster PV tracked efficiency with rapid convergence velocity. Vector‐oriented inverter control strategy depending on solar irradiance has been used for controlling the rate of converter/water flow. The proposed standalone PV pumping system has been tested under highly weather fluctuating conditions which provide efficient, accurate and feasible option for water pumping in remote areas. Experimental results have been justified using dSPACE (DS1104) practical environment.
Angsterkrankungen in der Rehabilitation
Authors: Chrysanthou Sophia , Köllner Volker 
Published: June 2022

ZusammenfassungAngststörungen gehören zu den häufigsten und sozialmedizinisch relevantesten psychischen Erkrankungen. Die richtige Diagnose und die Einleitung einer angemessenen Therapie sind von größter Bedeutung für die Prognose der Patienten:innen und für die Sicherung ihrer sozialen und beruflichen Teilhabe. Dieser Artikel soll daher einen Überblick über neue Entwicklungen auf dem Gebiet der Angststörungen geben, die für die Rehabilitation relevant sind.
Cortical Reorganization Following Psychoeducational Counselling and Residual Inhibition Therapy (RIT) in Individuals with Tinnitus
Authors: Vasudevan Harini , Palaniswamy Hari Prakash , Balakrishnan Ramaswamy , Rajashekhar Bellur 
Published: June 2022

AbstractIntroduction Psychoeducational counselling and residual inhibition therapy (RIT) are traditional approaches used in many clinics to manage tinnitus. However, neurophysiological studies to evaluate posttreatment perceptual and functional cortical changes in humans are scarce.Objectives The present study aims to explore whether cortical auditory-evoked potentials (CAEPs; N1 and P3) reflect the effect of modified RIT and psychoeducational counselling, and whether there is a correlation between the behavioral and electrophysiological measures.Methods Ten participants with continuous and bothersome tinnitus underwent a session of psychoeducational counselling and modified RIT. Perceptual measures and CAEPs were recorded pre- and posttreatment. Further, the posttreatment measures were compared with age and gender-matched historical control groups.Results Subjectively, 80% of the participants reported a reduction in the loudness of their tinnitus. Objectively, there was a significant reduction in the posttreatment amplitude of N1 and P3, with no alterations in latency. There was no correlation between the perceived difference in tinnitus loudness and the difference in P3 amplitude (at Pz).Conclusion The perceptual and functional (as evidenced by sensory, N1, and cognitive, P3 reduction) changes after a single session of RIT and psychoeducational counselling are suggestive of plastic changes at the cortical level. The current study serves as preliminary evidence that event-related potentials (ERPs) can be used to quantify the physiological changes that occur after the intervention for tinnitus.
Assessment Protocol for Candidates for Bone-Anchored Hearing Devices
Authors: Ueda Cynthia Harumi Yokoyama , Soares Renata Marcial , Jardim Isabela , Bento Ricardo Ferreira 
Published: June 2022

AbstractIntroduction The technology regarding bone-anchored hearing devices has been advancing. Nevertheless, complications are still often reported, which can impair treatment adherence and lead to discontinuation of use. There is a lack of studies conducted in tropical countries, where complications can be even greater, as well as standardized protocols for selection, indication and evaluation.Objective To characterize implanted patients from a Brazilian public institution and describe the medical and audiological assessment protocols to which they were submitted during the selection process and in the follow-up after surgery.Method An observational, cross-sectional study evaluating the medical records of patients with hearing loss and ear malformations and describing the care protocol through which they were treated.Results The medical records of 15 patients were reviewed: 6 received transcutaneous implants, and 9, percutaneous implants; 9 patients reported some type of skin lesion, 2 reported pain on the follow-up visit, and 3 had osseointegration failure. The time between surgery and activation ranged from 2 to 9 months. The median scores on the sentences, Sentences in Noise and Monosyllable tests were 100%, 60% and 80%, respectively.Conclusion It was possible to characterize the patients who received implants at the institution. The patients performed well in silence and had greater difficulty in noise. Even patients who had complications did not complain about the audibility and sound quality. It is essential to develop a model and to standardize the assessment and follow-up methods aimed at the benefit of users of bone-anchored hearing devices, as well as to enable the technico-scientific development in this field.
A Very Rare Cause of Thrombotic Peripheral Occlusion
Authors: Kretzschmar Daniel , Thieme Marcus , Aschenbach Rene , Schulze P. Christian , Möbius-Winkler Sven 
Published: June 2022

AbstractA 45-year-old healthy woman presented with claudication of the right leg. The resting ankle-brachial index (ABI) was reduced to 0.6, and a duplex scan revealed an occlusion of the right popliteal artery. Angiography presented a patent superficial femoral artery that ends above the knee joint. Laterally, there was delayed retrograde contrast filling of the popliteal artery. After exploring the internal iliac artery, we crossed a thrombotic occlusion of a persisting sciatic artery (PSA). Local thrombolysis with recombinant tissue plasminogen activator (1 mg/h) was initiated. The Angiography 18 hours later showed a reduction of thrombotic material and relevant stenosis in the proximal part of the vessel. Residual thrombus and the stenosis were covered by two stentgrafts (Gore Viabahn Endoprosthesis) that were stabilized by an interwoven stent (Supera). Final angiography displayed a patent sciatic artery and a three-vessel run off. Postinterventional ABI was normalized to 1.0. The magnetic resonance imaging 6 days after the intervention demonstrated a patent PSA again and a normal blood flow on the left leg. A PSA should be included in the differential diagnosis of lower limb ischemia or suspected aneurysm formation. We demonstrated the feasibility of an interventional approach with an excellent outcome in this case.
The Induction of Hypothyroidism during Gestation Decreases Outer Hair Cell Motility in Rat Offspring
Authors: Oliveira Priscila Feliciano de , Trindade Beatriz Barros Santos , Reis Paloma Fonseca Martins , Santos Tâmara Figueiredo do Carmo , Alves Julio Cesar Santana , Santana Demetrius Silva de , Badauê-Passos Jr Daniel 
Published: June 2022

Abstract
Introduction Perinatal hypothyroidism has a negative repercussion on the development and maturation of auditory system function. However, its long-term effect on auditory function remains unsettled.
Objective To evaluate the effect of prenatal hypothyroidism on the auditory function of adult offspring in rats.
Methods Pregnant Wistar rats were given the antithyroid drug methimazole (0.02% -1-methylimidazole-2-thiol– MMI) in drinking water, ad libitum, from gestational day (GD) 9 to postnatal day 15 (PND15). Anesthetized offspring from MMI-treated dams (OMTD) and control rats were evaluated by tympanometry, distortion product otoacoustic emission (DPOAE), and auditory brainstem response (ABR) at PNDs 30, 60, 90, and 120.
Results Our data demonstrated no middle ear dysfunction, with the OMTD compliance lower than that of the control group. The DPOAE revealed the absence of outer hair cells function, and the ABR showed normal integrity of neural auditory pathways up to brainstem level in the central nervous system. Furthermore, in the OMTD group, hearing loss was characterized by a higher electrophysiological threshold.
Conclusion Our data suggest that perinatal hypothyroidism leads to irreversible damage to cochlear function in offspring.
Transorbital Intracranial Penetrating Injury from a Homemade Gun: A Case Report
Authors: Trakulpanitkit Avika , Sungkaro Kanisorn 
Published: June 2022

AbstractA transorbital intracranial penetrating injury (TOPI) is an unusual traumatic brain injury that requires multidisciplinary management. TOPI may cause traumatic cerebrovascular injury (TCVI) and fatal brain damage with a high mortality rate. Herein, the authors described an 8-year-old male patient who was injured from a handmade gun; a projectile (marble) had penetrated the left frontal base via the left orbit. TOPI caused left anterior cerebral artery compression. A transorbital approach with an intraoperative transcranial approach on standby was performed to remove the foreign body. Postoperative intensive broad-spectrum antibiotics were administrated, and the patient made an uneventful recovery. In summary, TOPI is an uncommon TBI that risks TCVI. Intracranial vascular investigation should be performed before surgical management, and postoperative complications, such as meningitis, brain abscess, and delayed pseudoaneurysm, should be monitored.
A Preliminary Survey of the Postacute Symptoms of COVID-19 among Hospital-Discharged Patients and a Proposed Quantitative Framework for Assessment
Authors: Dutta Abhijit , Mitra Subhasis , Mitra Dalia 
Published: June 2022

Abstract
Background Following a massive outbreak of the coronavirus disease 2019 (COVID-19) pandemic, a significant number of survivors are still suffering from residual symptoms and complications. We designed a preliminary study to evaluate such symptom spectra in COVID-19 patients who had been discharged from the hospital.
Methods A telephone interview was conducted with 100-randomly chosen hospital-discharged COVID-19 survivors from the electronic patient record. The interview structure and method were developed by a panel of experts. A specially trained group conducted the interviews and data collection. The statistical analysis was performed in accordance with the data type (continuous and categorical). Group comparisons were also done between intensive care unit (ICU) versus general ward admission, and patients discharged between 3 and 12 weeks versus more than 12 weeks. Additionally, world clouds were used for better visualization of various prevalent symptoms.
Results Eighty-two participants were finally included for interview after preliminary screening. Fifty-three patients (64.6%) were male participants; 74.4% had at least one symptom. In general, fatigue, cough, insomnia, and shortness of breath were the most common persistent symptoms. Symptoms were more prevalent among the patients discharged from ICU compared with those discharged from the general ward. Cough, loss of appetite, depression, and incoherence were more common in patients after 12 weeks of hospital discharge.
Conclusion There is a wide range of persistent symptoms in the COVID-19 survivors who have been discharged from the hospital. Some symptoms arise or persisted even after 12 weeks. Based on the study results, available literature, and expert consensus, an assessment form has been developed that could be used for further research and clinical assessment of similar problems. Large-scale epidemiological study (longitudinal and cross-sectional) is needed to understand the nature and prevalence of the postacute phase of COVID-19 at the country level. The results of this study could inform the stakeholders and policymakers for taking necessary steps toward a further decision.
Design and implementation of an acoustic-vibration capacitive MEMS microphone
Authors: Duanmu Zheng , Kong Chunxiu , Guo Yangkuan , Zhang Xiaoqing , Liu Hongzhi , Zhao Chenglong , Gong Xiaofeng , Cai Chunhua , Ho Chenta , Wan Caixin 
Published: June 2022

A novel acoustic-vibration capacitive microelectromechanical system microphone is designed, fabricated, and implemented in this paper. The new microphone consists of a rigid diaphragm and mass blocks sensitive to low-frequency vibratory and sound signals. This sensor takes advantage of the semiconductor technology to design the capacitance sensor structure by surface micromachining technology, and the inertial mass blocks are shaped using the bulk silicon micromachining technology. The structure of the anti-stiction-dimple array is designed and deployed at the bottom of the diaphragm and the backplate to avoid the risk of sensor failure by vibration stiction. The bottom and top of the backplate are designed with an anti-humidity hydrophobic insulation protective layer, which avoids adsorption of moisture and attachment of foreign particles. The thickness of the mass blocks can be controlled by the combination of the dry and the wet micromachining method, which is sensitive to different frequency responses. This study can design and produce wafer level silicon with high consistency. The inertial mass proposed in this research can be achieved through a 6 in. wafer process with &gt;80% consistency when the thickness of the mass is around 300 μm. The sensing frequency can be reduced to below the 4 kHz frequency bandwidth with enhanced sensitivity in the ±0.5 dB range. Typical characteristic results show that the open-circuit sensitivity of the microphone is 12.63 mV/Pa (37.97 dBV/Pa) at 1 kHz (with 94 dB as the reference sound level). The total harmonic distortion and acoustic overload point are 0.21% and 121.2 dB sound pressure level, respectively. The electronic stethoscope is a typical application of this research, which can collect the characteristics and frequency spectrum of low-frequency cardiac vibration signals.
Single-dose ethanol intoxication causes acute and lasting neuronal changes in the brain
Authors: Knabbe Johannes , Protzmann Jil , Schneider Niklas , Berger Michael , Dannehl Dominik , Wei Shoupeng , Strahle Christopher , Tegtmeier Michèle , Jaiswal Astha , Zheng Hongwei , Krüger Marcus , Rohr Karl , Spanagel Rainer , Bilbao Ainhoa , Engelhardt Maren , Scholz Henrike , Cambridge Sidney B. 
Published: June 2022

Alcohol intoxication at early ages is a risk factor for the development of addictive behavior. To uncover neuronal molecular correlates of acute ethanol intoxication, we used stable-isotope–labeled mice combined with quantitative mass spectrometry to screen more than 2,000 hippocampal proteins, of which 72 changed synaptic abundance up to twofold after ethanol exposure. Among those were mitochondrial proteins and proteins important for neuronal morphology, including MAP6 and ankyrin-G. Based on these candidate proteins, we found acute and lasting molecular, cellular, and behavioral changes following a single intoxication in alcohol-naïve mice. Immunofluorescence analysis revealed a shortening of axon initial segments. Longitudinal two-photon in vivo imaging showed increased synaptic dynamics and mitochondrial trafficking in axons. Knockdown of mitochondrial trafficking in dopaminergic neurons abolished conditioned alcohol preference inDrosophilaflies. This study introduces mitochondrial trafficking as a process implicated in reward learning and highlights the potential of high-resolution proteomics to identify cellular mechanisms relevant for addictive behavior.
Single parameter scaling in the non-Hermitian Anderson model
Authors: Khan Niaz Ali , Muhammad Saz , Sajid Muhammad , Saud Shah 
Published: June 2022

Abstract
We numerically study the single parameter scaling (SPS) hypothesis in a non-interacting one-dimensional non-Hermitian Anderson model. We examine the role of non-Hermiticity in disorder potential on the SPS hypothesis at the band center. We report numerical calculations of the mean and variance of the distribution of the negative logarithmic conductance based on the linearized Landauer formalism in the perturbative regime at zero temperature. Our numerical finding indicates the violation of the SPS hypothesis for the non-Hermitian Anderson model. In particular, it turns out that the numerical SPS value of the Hermitian Anderson model is twice the magnitude of the SPS value of the non-Hermitian Anderson model for overall energies. Moreover, we obtain a relation between the localization length of the Hermitian and non-Hermitian Anderson models.
A novel approach in pharmaceutical analysis by laser induced breakdown spectroscopy combined with chemometric methods and artificial neural network
Authors: Farhadian A H , Mousavifard S S , Mollaei M 
Published: June 2022

Abstract
As a reliable method, Laser induced breakdown spectroscopy (LIBS) is widely applied to elemental analysis in different fields. In this research, LIBS was used to analyze pharmaceutical tablets. For this purpose, spectra from eight samples of three pharmaceutical classes were acquired; and after peaks recognition, they were investigated by principal component analysis (PCA) and artificial neural network (ANN). According to the results, due to the similarity of the main elements of different samples, it is difficult to distinguish them by spectra; therefore, PCA was used to make a better comparison between the samples. Apart from that, unknown samples were identified and predicted through the ANN.