bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of the COVID-19 pandemic on cardiac implantable electronic device implantation in China: Insights from 2 years of changing pandemic conditions
Authors: Cheng Chen-di , Zhao Shuang , Jiang Jiang , Lin Na , Li Ping , Ning Xiao-hui , Zhang Shu 
Published: November 2022

BackgroundA substantial reduction in the number of cardiac implantable electronic device (CIED) implantation was reported in the early stages of the COVID-19 pandemic. None of the studies have yet explored changes in CIED implantation during the following pandemic.ObjectiveTo explore changes in CIED implantation during the COVID-19 pandemic from 2020 to 2021.MethodsFrom 2019 to 2021, 177,263 patients undergone CIED implantation from 1,227 hospitals in China were included in the analysis. Generalized linear models measured the differences in CIED implantation in different periods. The relationship between changes in CIED implantation and COVID-19 cases was assessed by simple linear regression models.ResultsCompared with the pre-COVID-19 period, the monthly CIED implantation decreased by 17.67% (95% CI: 16.62–18.72%, p &lt; 0.001) in 2020. In 2021, the monthly number of CIED implantation increased by 15.60% (95% CI: 14.34–16.85%, p &lt; 0.001) compared with 2020. For every 10-fold increase in the number of COVID-19 cases, the monthly number of pacemaker implantation decreased by 429 in 2021, while it decreased by 676 in 2020. The proportion of CIED implantation in secondary medical centers increased from 52.84% in 2019 to 56.77% in 2021 (p &lt; 0.001). For every 10-fold increase in regional accumulated COVID-19 cases, the proportion of CIED implantation in secondary centers increased by 6.43% (95% CI: 0.47–12.39%, p = 0.036).ConclusionThe impact of the COVID-19 pandemic on the number of CIED implantation is diminishing in China. Improving the ability of secondary medical centers to undertake more operations may be a critical way to relieve the strain on healthcare resources during the epidemic.
Association of leisure activity changes and reversion from mild cognitive impairment to normal cognitive function among older adults: A prospective cohort study
Authors: Xu Xin Yi , Wang Shan Shan , Niu Li , Leung Isaac Sze Him , Tian Qing Bao 
Published: November 2022

BackgroundOlder adults with mild cognitive impairment (MCI) have the possibility of reverting to normal cognitive function. Leisure activity engagement (LAE) plays a critical role in the progress of the cognitive function. A better understanding of the dynamic relationship between LAE and MCI reversion would inform the implementation of preclinical dementia interventions. This study aimed to investigate the association between change patterns of LAE and MCI reversion among older adults using the Chinese Longitudinal Healthy Longevity Survey (CLHLS) database.Study designLongitudinal population-based study.MethodsOlder adults with MCI at the baseline were enrolled in this study. Information about cognitive function, overall, cognitively stimulating, physically active/demanding, and socially engaged LAE was collected at baseline and follow-up. Adjusted hazard ratios (HRs) for reversion and 95% confidence intervals (CIs) were calculated by Cox hazard models with time as the underlying time metric. We also assessed potential effect modifications by creating a cross-product of the stratifying variable with LAE change patterns in the fully adjusted model.ResultsThe restricted cubic spline showed that the association between LAE change scores and MCI reversion rate was statistically significant and nonlinear (p&lt;0.01). Taking participants in the low–low group as a reference, participants in the low–medium, low–high, medium–medium, medium–high, high–medium, and high–high groups had increased possibilities of MCI reversion with HRs (95% CI) of 2.19 (1.57–3.06), 2.97 (2.13–4.13), 0.87 (0.64–1.19), 2.28 (1.71–3.03), 2.78 (2.10–3.69), 1.93 (1.43–2.59), and 2.74 (2.09–3.60), respectively. Further stratified models showed that the impact of LAE change patterns on MCI reversion varied in different ages (nonagenarian, octogenarian, and younger elderly) and gender.ConclusionsParticipants who maintained the highest LAE had the greatest possibility of MCI reversion. Meanwhile, a higher level of LAE maintenance was associated with the increased possibility of MCI reversion. These results provide a practical message to older adults about how dynamic changes in LAE are associated with improved cognitive function.
BCR-UNet: Bi-directional ConvLSTM residual U-Net for retinal blood vessel segmentation
Authors: Yi Yugen , Guo Changlu , Hu Yangtao , Zhou Wei , Wang Wenle 
Published: November 2022

BackgroundHigh precision segmentation of retinal blood vessels from retinal images is a significant step for doctors to diagnose many diseases such as glaucoma and cardiovascular diseases. However, at the peripheral region of vessels, previous U-Net-based segmentation methods failed to significantly preserve the low-contrast tiny vessels.MethodsFor solving this challenge, we propose a novel network model called Bi-directional ConvLSTM Residual U-Net (BCR-UNet), which takes full advantage of U-Net, Dropblock, Residual convolution and Bi-directional ConvLSTM (BConvLSTM). In this proposed BCR-UNet model, we propose a novel Structured Dropout Residual Block (SDRB) instead of using the original U-Net convolutional block, to construct our network skeleton for improving the robustness of the network. Furthermore, to improve the discriminative ability of the network and preserve more original semantic information of tiny vessels, we adopt BConvLSTM to integrate the feature maps captured from the first residual block and the last up-convolutional layer in a nonlinear manner.Results and discussionWe conduct experiments on four public retinal blood vessel datasets, and the results show that the proposed BCR-UNet can preserve more tiny blood vessels at the low-contrast peripheral regions, even outperforming previous state-of-the-art methods.
Crisis communication strategies for health officials
Authors: Su Zhaohui , Zhang Huan , McDonnell Dean , Ahmad Junaid , Cheshmehzangi Ali , Yuan Changrong 
Published: November 2022

BackgroundMixed messaging among health officials are prevalent amid COVID-19. Crisis communication strategies have the potential to help health officials effectively address issues such as mixed messages and improve their crisis communication efficacy. However, there is a dearth of insights in the literature. Therefore, to bridge the research gap, this study aims to examine practical strategies health officials can utilize to improve their crisis communication efficacy.MethodsA literature review on effective crisis communication strategies amid COVID-19 was conducted in PubMed, Scopus, and PsycINFO, with a focus on scholarly literature published in English.ResultsThe findings of the study identified the following strategies that health officials can utilize to improve their crisis communication capabilities: (1) develop fact-based, transparent, and accountable messaging, (2) utilize people-centered and empathetic persuasive strategies, and (3) leverage international collaboration for consistent messaging and comprehensive crisis communication.ConclusionCOVID-19 has challenged health officials with unprecedented crisis communication duties and responsibilities. In this study, we underscored the importance of effective crisis communication amid global health emergencies like COVID-19, and identified communication strategies health officials could adopt or adapt to improve their crisis communication efficacy. Future research could explore strategies health officials can use to better communicate with government officials and media professionals to further help health officials improve their crisis communication capabilities, their abilities to avoid preventable miscommunication or mixed messaging, and in turn, society's collective strengthen in curbing and controlling the pandemic.
MET gene alterations predict poor survival following chemotherapy in patients with advanced cancer
Authors: Ko Jihoon , Jung Jaeyun , Kim Seung Tae , Hong Jung Yong , Park Sehhoon , Park Joon Oh , Park Young Suk , Lim Ho Yeong , Ahn Soomin , Kim Kyoung-Mee , Kang Won Ki , Lee Jeeyun 
Published: November 2022

Background: To aid in oncology drug development, we investigated MET proto-oncogene receptor tyrosine kinase gene aberrations in 2,239 oncology patients who underwent next-generation sequencing (NGS) in clinical practice.Materials and methods: From November 2019 to January 2021, 2,239 patientswith advanced solid tumors who visited oncology clinics underwent NGS. The NGS panel included &gt;500 comprehensive NGS tests using archival tissue specimens. Programmed death-ligand 1(PD-L1) 22C3 assay results and clinical records regarding initial chemotherapy were available for 1,137 (50.8%) and 1,761 (78.7%) patients, respectively for overall survival (OS) analysis.Results: The 2,239 patients represented 37 types of cancer. The NGS panel included &gt;500 genes, microsatellite instability status, tumor mutational burden, and fusions. The most common cancer types were colorectal (N = 702), gastric (N = 481), and sarcoma (N = 180). MET aberrations were detected in 212 patients. All MET-amplified tumors had microsatellite stable status, and 8 had a high tumor mutational burden. Of 46 patients with MET-amplified cancers, 8 had MET-positive protein expression by immunohistochemistry (2+ and 3+). MET fusion was detected in 10 patients. Partner genes of MET fusion included ST7, TFEC, LRRD1, CFTR, CAV1, PCM1, HLA-DRB1, and CAPZA2. In survival analysis, patients with amplification of MET gene fusion had shorter OS and progression-free survival (PFS) than those without. Thus, MET aberration was determined to be a factor of response to chemotherapy.Conclusion: Approximately 2.1% and 0.4% of patients with advanced solid tumors demonstrated MET gene amplification and fusion, respectively, and displayed a worse response to chemotherapy and significantly shorter OS and PFS than those without MET gene amplification or fusion.
Consequence of Blowby Flow and Idling Time on Oil Consumption and Particulate Emissions in Gasoline Engine
Authors: Berthome Vincent , Chalet David , Hetet Jean-François 
Published: November 2022

Pollutant emission standards and, in particular, those concerning particles from an internal combustion engine (ICE) are becoming increasingly restrictive. Thus, it is important to determine the main factors related to the production of particulate matter. In this article, the phenomenon of oil sweeping by the blowby gases between the rings/piston/cylinder is investigated. First, a blowby gas simulation model based on experimental results from a Turbocharged Gasoline Direct Injection (TGDI) is developed. From this model, it is possible to characterise the amount of oil swept by the blowby gases. This depends on the endgap position of both the compression and sealing rings. It also depends on the intensity of the blowby flow rate, which is highest at low rpm and high load. At 1500 rpm and full load, this flowrate exceeds 25 mg.cycle−1. From this result, it is possible to quantify the amount of oil swept by these gases as a function of the endgap position. For θrings=180°, the quantity of oil swept rises to 20 µg.cycle−1 while for θrings=30°, this decreases to 6 µg.cycle−1. The oil concentration of the blowby gas has a direct impact on the particulate emissions because the oil concentration of the backflow gas is inversely proportional to the blowby gas flowrate. As the backflow gases return to the cylinder, the oil oxidises and produces particles. Therefore, it is essential to control the oil concentration of the backflow gases. In addition, the simulation model shows the blowby flowrate becomes negative and decreases to −3.4 mg. cycle−1 in idle conditions. The amount of oil swept by the blowby is no longer directed towards the oil pan, but towards the piston crown. This phenomenon of oil storage of the piston crown in idle condition is proportional to the duration of the idle time. In order to confirm these results, experimental tests are carried out on a TGDI engine. It appears that when the idling time changes from 0 s to 7 s between two strictly identical accelerations, the level of particulate emissions is multiplied by 1.3. When the idling time changes from 0 s to 22 s between two strictly identical accelerations, the level of particulate emissions is multiplied by 3. These results confirm the mechanism of oil storage at idle highlighted by the simulation model.
Historicização do processo de alfabetização em contextos inclusivos
Authors: Oliveira Marineiva Moro Campos de , Veiga Karine Odete , Tedesco Anderson Luiz 
Published: November 2022

O presente artigo tem como objetivo apresentar as pesquisas correlatas do objeto de investigação desta pesquisa, a alfabetização no ensino inclusivo, destacando a articulação desses elementos na constituição histórica do processo educacional inclusivo. Apresentam-se no decorrer do trabalho os fundamentos e concepções da organização do processo de alfabetização e do ensino inclusivo de sua institucionalização aos dias atuais. Para isso, realizaram-se buscas de pesquisas correlatas sobre a alfabetização e ensino inclusivo no banco de produções científicas da Capes. A busca possibilitou compreender como o processo histórico de alfabetização foi organizado no decorrer dos tempos, os métodos e as teorias que balizaram o ensino e a aprendizagem da leitura e da escrita, apontando as aproximações e contradições entre os elementos que nortearam o processo. As considerações finais apontam que ao longo da história a alfabetização foi estruturada por métodos e perspectivas teóricas que conduziram o processo à fragmentação, à hierarquização e à desqualificação. Ainda, evidenciam a necessidade de compreender que a inserção no campo de alfabetização pressupõe assumir o compromisso com a transformação social na busca pela emancipação dos sujeitos a partir do ensino e da aprendizagem dos conhecimentos científicos da leitura e da escrita.
Pensar el vínculo. Hacia un ensayo sobre el nexo entre las izquierdas y el movimiento obrero
Authors: Ceruso Diego , Mangiantini Martín 
Published: November 2022

El presente ensayo se propone analizar el modo en el que la historiografía argentina exploró y problematizó la vinculación entre las izquierdas y la clase trabajadora. Algunas preguntas orientan nuestra reflexión. ¿Es posible cualificar el alcance de la inserción de una organización revolucionaria en el seno del proletariado y en sus organismos de representación? ¿Qué variables se pueden utilizar para analizar o dimensionar la existencia real de tal influencia? ¿Qué particularidades históricas y políticas deben atenderse? ¿Cuáles son los elementos que podrían ponderarse para capturar las especificidades de cada caso? El objetivo no consiste en realizar un mero recorrido historiográfico sino presentar una serie de argumentaciones teóricas y metodológicas que colaboren a la reflexión sobre esta ligazón en el marco de la historia argentina del siglo XX.
A Torsion-Based Rheometer for Measuring Viscoelastic Material Properties
Authors: Asp Merrill , Jutzeler Elise , Kochanowski Jakub , Kerr Katherine , Song Dawei , Gupta Sarthak , Carroll Bobby , Patteson Alison 
Published: November 2022

ABSTRACT
Rheology and the study of viscoelastic materials are an integral part of engineering and the study of biophysical systems. Tissue rheology is even used in the study of cancer and other diseases. However, the cost of a rheometer is feasible only for colleges, universities, and research laboratories. Even if a rheometer can be purchased, it is bulky and delicately calibrated, limiting its usefulness to the laboratory itself. The design presented here is less than a tenth of the cost of a professional rheometer. The design is also portable, making it the ideal solution to introduce viscoelasticity to high school students as well as for use in the field for obtaining rheological data.
Abordagens teóricas de métodos regionais na perspectiva da dialética
Authors: Carrieri Raquel Augusta Melilo , Ascenção Valéria de Oliveira Roque 
Published: November 2022

É apresentada, neste artigo, parte das primeiras análises da revisão bibliográfica que compõe uma pesquisa de doutoramento. Esta pesquisa tem como um dos objetivos, e procedimentos, analisar as possibilidades da abordagem de regionalização na geografia escolar que permitam o desenvolvimento do raciocínio geográfico. Por isso, justifica-se o enfoque sobre método regional. Apresenta-se, neste artigo, a investigação do método regional nas correntes de pensamento associadas à geografia crítica. Os dois métodos regionais que serão apresentados, e contrastados, foram defendidos por Aluízio Duarte e Roberto Lobato Correia. O primeiro geógrafo advoga a aplicação do conceito de totalidade como suporte de análise e divisão regional. Já Roberto Lobato Correia defende a aplicação de uma das leis da dialética no processo de divisão regional: a lei do desenvolvimento desigual e combinado. Apesar das diferenças, os dois autores atribuem as mudanças na estrutura dos espaços às forças do capital internacional. Não há, entre essas e diversas outras opções teóricas, um método acabado e mais correto. Há aquele que se adequará, em termos de linguagem e conteúdo, às questões de pesquisa.
Influence of the temperature and substrate modification on the formation of continuous GaSb film on Si(111) by solid phase epitaxy
Authors: Chusovitina S. V. , Subbotin E. Y. , Chusovitin E. A. , Goroshko D. L. , Dotsenko S. A. , Pyachin S. A. , Gerasimenko A. V. , Gutakovskii A. K. 
Published: November 2022

Abstract
The solid-state formation of gallium antimonide on Si(111) from a stoichiometric mixture of GaSb in the temperature range of 300 °C–500 °C and thicknesses of 12–40 nm was studied under ultrahigh vacuum conditions. The influence of the preformed GaSb seed islands on the morphology, composition, and structure was studied. It has been found that at 300 °C a strained continuous polycrystalline film is formed, which rupture at 350 °C. It has been shown that a continuous single-crystal GaSb film grows at 400 °C–500 °C if the sample is annealed at a weak antimony flow. This is also facilitated by the preliminary formation of a high density of nanosize GaSb seed islands. As a result, a continuous relaxed film with epitaxial relations GaSb(111)∣∣Si(111) and GaSb[1–10]∣∣Si[1–10] was obtained from a GaSb mixture 40 nm thick at 500 °C. We demonstrate a possibility of direct formation of GaSb on Si(111) without buffer layers of other chemical elements.
Pendampingan Penyusunan Laporan Keuangan Berdasarkan PSAK ETAP di BUMNag Baringin Saiyo Kecamatan Lima Kaum
Authors: Fitria Nita , Fitri Sri Adella , Rahmi Mega , Guspendri Nasfizar , Marlin Khairul 
Published: November 2022

Financial reports can have a positive impact on the development of BUMNag. From financial reports, systematic data and information can be obtained on the business so as to assist in making decisions. The presentation of financial statements must be good and in accordance with the criteria that are understandable, relevant, reliable, and comparable, so that it can be useful in making decisions that affect the performance and image of the company going forward. In making financial statements, a company must comply with existing Financial Accounting Standards. In compiling the financial statements of BUMNag Baringin Saiyo encountered several obstacles, namely the problem of existing human resources, a lack of knowledge of accounting knowledge which was not sufficient to make account adjustments, and the preparation of financial statements in accordance with Financial Accounting Standards. The purpose of the service activity is to prepare financial reports for BUMNag Baringin SAIYO according to Financial Accounting Standards. The resulting financial statements consist of a Profit and Loss report, a Statement of Financial Position, and notes to the financial statements.
Meningkatkan Pendapatan Dengan Usaha/Bisnis di Masa Pandemi
Authors: Gazali Masfar , Widowati Dorina , Lukito Nico 
Published: November 2022

Turbulensi masih terjadi pada kasus pandemi di Indonesia. Sempat turun di awal tahun, di semester kedua kasus melonjak tajam dan kemudian kembali menerpa menjelang kuartal ketiga. Kondisi ini menuntut pemerintah merancang sistem yang efektif untuk membendung laju turbulensi sehingga momentum penurunan ini dapat terus berlanjut. Selain itu, pemerintah juga perlu terus berpikir untuk menjaga keseimbangan sektor kesehatan dan sektor ekonomi secara keseluruhan. Dua hal utama dalam pembangunan ini adalah sektor vital yang paling terdampak, namun karena peristiwa pandemi keduanya seolah berjalan menjauh. Sebagai langkah strategis dalam membendung peningkatan kasus COVID-19 yang sangat signifikan, Pemberlakuan Pembatasan Kegiatan Masyarakat (PPKM) menjadi langkah awal yang dipilih pemerintah. Hal ini menimbulkan dampak yang tidak mungkin dihindari, yaitu memperlambat perputaran roda ekonomi. Komunitas dengan kelompok bisnis terbawah adalah yang paling terpukul dalam pembatasan ini. Tujuan kegiatan pengabdian ini adalah untuk memberikan dan membagikan informasi, ide-ide tentang peluang usaha/bisnis yang disesuaikan dengan modal minim pada masa pandemi, dan meningkatkan pendapatan usahanya yang mudah diaplikasikan dalam kondisi pandemi ini. Tentunya program PPKM ini perlu didukung dan diimbangi dengan bantuan sosial kepada mereka yang merasakan dampak ekonomi paling besar yang muncul. Menurut Badan Pusat Statistik, dunia usaha di Indonesia saat ini didominasi oleh Usaha Mikro Kecil (UMK), dan jumlahnya mencapai 26 juta usaha atau 98,68 persen dari total usaha non pertanian di Indonesia. Usaha ini mampu menyerap 59 juta orang atau sekitar 75,33 persen dari total tenaga kerja non pertanian. Tentu kita tidak bisa hanya mengandalkan Belanja Bantuan Sosial untuk menjaga ketahanan masyarakat yang paling terdampak. Setiap lapisan masyarakat juga dapat memberikan perannya masing-masing untuk menjaga perputaran ekonomi saat ini. Dana bantuan pemerintah yang cukup besar tidak akan berarti jika salah objek mendapat bantuan. Untuk itu perlu dukungan penuh dari masyarakat untuk mengontrol dan menjaga agar program ini tepat sasaran, tepat guna, dan mampu memberikan efek yang paling optimal. Selain itu, upaya bersama masyarakat untuk saling berbagi, dan saling menjaga kesehatan juga menjadi elemen penting dalam “perang” kita melawan gejolak pandemi ini.