bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tasa de éxito de los minitornillos infracigomáticos considerando su diseño y técnicas de inserción. Una revisión
Authors: Rodríguez-Rimachi María Emely , Malpartida-Pacheco Mónica Ivette , Olazábal-Martínez Walter Carlos 
Published: October 2022

Los minitornillos ofrecen la posibilidad de realizar movimientos dentales, lo que minimiza los efectos secundarios no deseados y potencia la eficacia. Los minitornillos extraalveolares son ideales ya que proporcionan una excelente estabilidad primaria y evitan estructuras anatómicas. Sin embargo, en algunos casos se pierde la estabilidad primaria antes de lograr el éxito de la mecánica utilizada y, por lo tanto, se deben determinar las causas más probables de la falla. El propósito de esta revisión fue analizar la tasa de éxito de los minitornillos infracigomáticos, considerando su diseño y las técnicas de inserción utilizadas. La recolección de datos de esta revisión bibliográfica se realizó mediante la búsqueda en PubMed, Wiley, sitios de Google Scholar, SciELO, Elsevier y Dialnet para publicaciones realizadas desde 2003 hasta junio de 2022. La búsqueda se realizó el 10 de junio de 2022 y se utilizaron las siguientes palabras clave: cresta infracigomática, minitornillos, anclaje y estabilidad. Se analizaron y discutieron diferentes temas destacando su relevancia clínica. Tras analizar los 798 artículos, se excluyeron 566. Los restantes fueron reanalizados y 153 resultaron excluidos por el título o resumen, y 33 por la metodología. Finalmente, quedaron 46 artículos. Tras analizar exhaustivamente todos los artículos incluidos, este estudio concluye que la aleación del minitornillo (acero inoxidable o titanio), la perforación del seno maxilar y la zona de colocación (mucosa adherida o mucosa móvil) no influyen en la supervivencia del minitornillo. La evidencia también indica que el porcentaje de fracaso es menor en los minitornillos infracigomáticos en comparación con los intrarradiculares. Los ortodoncistas pueden incluir con confianza y seguridad minitornillos infracigomáticos en diferentes procedimientos de ortodoncia.
Efectividad del blanqueamiento dental en pacientes con tratamiento de ortodoncia fija activa: Una revisión narrativa
Authors: Santillán-Guerra Adrián Mauricio , Sánchez-Rodríguez Angie Melanie 
Published: October 2022

Introducción: Actualmente, la estética dental durante el tratamiento de ortodoncia fija es una opción requerida por los pacientes, debido a las frecuentes pigmentaciones que se pueden presentar en el esmalte dental como consecuencia de una inadecuada higiene bucal y la retención de placa provocada por la aparatología fija. Objetivo: Determinar la efectividad del blanqueamiento dental y sus efectos secundarios durante el tratamiento de ortodoncia fija activa, como alternativa de tratamiento estético en determinados casos que lo ameriten. Materiales y metodos: Esta revisión narrativa evaluó 35 artículos científicos de las fuentes de información Medline (vía PubMed), Embase, Scopus, SciELO y LILACS de los últimos 10 años, publicados en español, portugués e inglés. Se incluyeron 17 artículos que cumplieron con los criterios de selección, los cuales fueron ensayos clínicos aleatorizados y estudios observacionales, estudios in vitro y estudios in vivo que evaluaron el aclaramiento dental en consultorio, realizados en pacientes que utilizaban tratamiento de ortodoncia fija en ese momento. Se excluyeron revisiones sistemáticas, informes de casos y editoriales. Resultados: Se observo que el blanqueamiento dental en pacientes con tratamiento de ortodoncia activa afecta mínimamente la adherencia del aparato de ortodoncia a la superficie del diente. Además, algunos estudios observaron que los brackets interfieren en la extensión del aclaramiento dental, al evidenciar áreas ligeramente más oscuras. Conclusiones: El blanqueamiento dental durante el tratamiento de ortodoncia se puede dar de manera eficiente en la práctica clínica, dependiendo del requerimiento estético del paciente. Sin embargo, es un procedimiento recomendado en ciertos casos de gran necesidad de estética inmediata, ya que el material con el que se instalan los Brackets sobre la superficie dentaria interferirá en la extensión del material aclarante, lo que da como resultado una tonalidad más oscura en ese sector y diferente del tejido circundante. Asimismo, intervendrá en la adhesión a la superficie dentaria, por lo que existen muchas probabilidades de que el aparato de ortodoncia pueda desprenderse.
The connection between sustainable brand and business in the Amazon Forest – Local business owner’s POV
Authors: Diego Luiz , Holanda Francisco Sandro Rodrigues , de Menezes Pedro Vinícius Bertulino , Oliveira Catuxe Varjão de Santana , Villwock Ana Paula Schervinski , Pedrotti Auceu 
Published: October 2022

Abstract

The rhetorictoward entrepreneurship in the Amazon region highlights the importance of sustainable actions developed by local brands. But little attention has been given to the entrepreneur's vision regarding the results of said applied practices. This study seeks to understand the perception of entrepreneurs from their business model related to the connection of the Amazon rainforest brand. The study consisted of semi structuredinterviews with 7 brands of Amazonian products using grounded theory. The results show that entrepreneurs understand that the reach of the social dimension depends on the trifecta articulation: entrepreneurs, native people, and ecological and cultural dimensions codependence directly on shared traditional knowledge. It is observed that the political dimension is still little developed in the region and its effects on products are inconsequential. The economic dimension is still little favored using environmentally sustainable brands. Finally, the territorial dimension depends on the creation of permanent protection areas as well as agroforestry systems.
Multidrug Resistance Tracing by Plasmid Profile Analysis and the Curing of Bacteria from Different Clinical Specimens
Authors: Okoye Ebele L. , Kemakolam Christian , Ugwuoji Emmanuel T , Ogbonna Ifeoma 
Published: October 2022

Abstract
Human-pathogenic bacteria resistant to one or multiple antibiotics have dramatically increased worldwide in the past decades. These bacteria possess great danger, have become a global issue and it is now impossible to avoid developing strategies for the restoration of treatment options against infections caused by them. This research aims at profiling plasmids of multidrug-resistant bacteria from various clinical specimens such as ear exudate, sputum, urethral swab, wound swab, urine from the catheter, urine, nasal swab, high vaginal swab, stool, eye swab and blood at Chukwuemeka Odumegwu Ojukwu University Teaching Hospital Awka, Anambra State, Nigeria. Our investigation used the Agar diffusion method for susceptibility tests and identification of multidrug-resistant bacteria before plasmid extraction and gel electrophoresis. A plasmid curing test was performed with 10% Sodium Dodecyl Sulphate. Of the 860 bacteria whose resistance profile was determined, only 42 were multidrug-resistant. These bacteria include Pseudomonas aeruginosa 16 (38.10%), Staphylococcus aureus 12 (28.57%), Escherichia coli 9 (21.43%), and Klebsiella pneumoniae 5(11.90%). The molecular weight of their plasmids ranges between 20.884kbp and 187.50kbp. As indicated by the plasmid bands, some bacteria had similar molecular weight while others had no plasmid. The bacterial pattern of the post-curing sensitivity test showed that the bacteria with plasmid bands were cured as they became susceptible to the drugs they were previously resistant to, while the bacteria without plasmid bands remained resistant to the antibiotics. This implies that the latter’s multidrug resistance is non-plasmid mediated. Our analyses highlight the relationship between plasmids and multidrug resistance as well as the role of plasmids in the transmission of drug resistance across bacteria. Thus, in order to lessen the burden that multidrug-resistant bacteria cause and to improve bacterial infections treatments, there should be continued surveillance and periodic research on antibiotic resistance patterns of bacteria from various clinical settings.
COVID-19 Stock Market Experiences and Local Investors’ Investment Decisions in Lagos, Nigeria: A Pilot Study
Authors: Ekechukwu Iheanyi Valentine , Adejoh Ojima Samuel , Dinne Chinedu Ernest , Nwogu Joseph N 
Published: October 2022

Abstract
Economic activities were yet to pick up following the devastating effects of Covid-19 pandemic on stock market in Nigeria. Major cities were on complete lockdown for months leading to another phase of stock market crisis in 2021. This study explored Covid-19 stock market experiences and local investors’ investment decisions in Lagos, Nigeria. Organic theory of Emile Durkheim was adopted as framework, whereas exploratory design was employed. The study utilized purposive and snowballing sampling techniques, using purely qualitative research instruments with a sample of fifty-three (53) interviewees. Forty In-depth interviews (IDI), four Case Studies and nine Key informants (KII), three each were purposively selected from staff of Nigerian Exchange Ltd (NGX), Securities and Exchange Commission (SEC) and Stockbrokers in Lagos State based on their in-depth professional knowledge about stock market operations. The qualitative data were content analyzed. The result of the study showed that local investors’ Covid-19 stock market experiences have greatly affected their present investment decisions, hence local investors’ investment apathy currently affecting the Nigerian stock market. There is need for restoration of investors’ confidence in the Nigerian stock market.
Establishment of a human pluripotent stem cell-derived MKX-tdTomato reporter system
Authors: Fujisawa Yuki , Lu Ming , Yamada Daisuke , Takao Tomoka , Takarada Takeshi 
Published: October 2022

Abstract
Tendon regeneration is difficult because detailed knowledge about tendon progenitor cells (TPCs), which produce tenocytes to repair tendon tissue, has not been revealed. Mohawk homeobox (MKX) is a marker of TPCs or tenocytes, but a human pluripotent stem cell (hPSC)-based reporter system that visualizes MKX+ cells has not been developed. Here we established an hPSC-derived MKX-tdTomato reporter cell line and tested the induction ratio of MKX-tdTomato+ cells using our stepwise/xeno-free differentiation protocol. MKX-tdTomato + cells were generated with high efficiency and expressed tendon-specific markers, including MKX, SCX, TNMD, and COL1A1. Our MKX-tdTomato hPSC line would be a useful tool for studying the development or regeneration of tendon tissue.
Attack detection in IoT-Fog computing environment using hybrid optimization-based Generative Adversarial Network
Authors: N Pallavi K , V Ravi Kumar 
Published: October 2022

Abstract
Internet of Things (IoT) is considered the rapidly growing paradigm in the evolution of computing. A number of attack detection methods is introduced for detecting the attacks in IoT-Fog computing, but achieving significant result poses a complex task due to the requirements of the IoT devices, like distribution, low latency, limitation of resources, and scalability. Hence, an effective attack detection method is designed using the proposed Sail Fish Cat Spider-based Generative Adversarial Network for detecting the attacks in the IoT framework. The proposed SFCS is developed by the integration of Sail Fish Optimization (SFO) with Cat Swarm Optimization (CSO) and Spider Monkey Optimization (SMO), respectively. Here, the features are selected from the data using Minkowski distance, and the process of attack detection is accomplished using GAN. However, the deep learning classifier named GAN is trained using the proposed SFCS optimization algorithm. The deep learning classifier is more effective in detecting cyber-attacks in the IoT environment. However, the average values of the proposed SFCS-based GAN obtained by considering the metrics, recall, precision, and F-measure is specified with the values of 85.787%, 85.165%, and 85.247% for DoS attack, and recall, precision, and F-measure of 85.340%, 85.653%, and 85.243% for Fuzzers attack.
Learning Target Point Seeking Weights Spatial-Temporal Regularized Correlation Filters for Visual Tracking
Authors: JIANG Wen-Tao , WANG Zi-Min , ZHANG Sheng-Chong , ZHOU Zi-Qi 
Published: October 2022

Abstract
Spatial-temporal regularized correlation filtering (STRCF) is an effective tracking algorithm. Still, problems such as target occlusion, background clutter and out of view caused by target movement are inevitable in the running process. This paper proposes a Target Point Seeking Weights Spatial-Temporal Regularized Correlation Filters (TP-STRCF) to tackle target loss. The alternating direction method of multipliers (ADMM) is used to simplify the spatial-temporal regularized term in the objective function, obtain the optimal solution of the filter and auxiliary factor, reduce the algorithm's complexity, and realize the adaptability of time and space. The target weight response model is obtained through the target point finding weight, the target motion information is extracted, the target motion state and motion trajectory are predicted, and the interference information such as the algorithm's ability to identify the target and the ability to distinguish the target is enhanced. With the help of the weighted least squares method, the maximum response value of the weight is obtained, and the target position is determined. Experiments show that, compared with other mainstream correlation filtering algorithms, the proposed algorithm has higher tracking accuracy and stronger robustness under complex conditions.
Urolithin A reduces amyloid-beta load and improves cognitive deficits uncorrelated with plaque burden in a mouse model of Alzheimer’s disease
Authors: Ballesteros-Alvarez Josue , Nguyen Wynnie , Sivapatham Renuka , Rane Anand , Andersen Julie K 
Published: October 2022

Abstract
In recent years, a burgeoning body of evidence has pointed to age-related dysfunction in neuronal autophagy as playing a prominent role in neuropathology associated with Alzheimer’s disease (AD). In the present study, we investigated the effects of urolithin A (UA), a metabolite generated from ellagic acid via its metabolism by gut bacteria, as an autophagy activator with potential neuroprotective activity. WT and 3xTg-AD mice were administered long-term intermittent dietary supplementation with UA. UA was found to prevent deficits in spatial memory, cued fear response and exploratory behavior in this model. It also decreased the Aβ plaque burden in areas of the hippocampus where these protein deposits are prominent in the model. Interestingly, correlation analyses demonstrate that Aβ plaque burden positively correlates with enhanced spatial memory in 3xTg mice on a control diet but not in those supplemented with UA. In contrast, Aβ42 abundance in cortical and hippocampal homogenates negatively correlate with spatial memory in UA-fed mice. Our data suggest that plaque formation may be a protective mechanism against neurodegeneration and cognitive decline and that targeting the generation of proteotoxic Aβ species might be a more successful approach in halting disease progression than targeting plaque formation. UA was also found to extend lifespan in normal aging mice. Mechanistically, we demonstrate that UA is able to induce autophagy and to increase Aβ clearance in neuronal cell lines. In summary, our studies reveal UA, likely via its actions as a autophagy inducer, is capable of removing Aβ from neurons and its dietary administration prevents the onset of cognitive deficits associated with pathological Aβ deposition the 3xTg AD mouse model as well as extending lifespan in normal aging mice.
Green Synthesis of recyclable reduced graphene oxide-gold nanocatalyst using Alstonia scholaris: Applications in waste water purification and microbial field
Authors: Das Piu , Bairy Bapan , Ghosh Sanjukta , Ghosh Raktim , Dam Somasri , (Sen) Moni Baskey 
Published: October 2022

Abstract

A novel green synthesis of reduced gold-graphene oxide (Au-RGO) nanocomposite was fabricated through simple heating method using Alstonia scholaris ( A .scholaris) bark extract. The synthesized nanocatalyst was characterized by X-ray diffraction (XRD), UV-Visible spectroscopy, Fourier transformed infrared spectroscopy (FT-IR). Transmission electron microscopy (TEM) and size distribution study have been investigated to find the dimension of the gold nanoparticles (Au NPs) grown on reduced graphene oxide (RGO) surface. Subsequently, both the catalytic and photocatalytic performances of this nanocomposite were evaluated by using different organic hazardous dyes and a tentative photocatalytic reaction mechanism was discussed depending on the energy band position. To find the effect on different bacterial strains, antibacterial and antiprotozoal studies have been carried out with this nanocomposite.
Identification and Sequence Analysis of B-hordein Genesfrom 18 Barley Cultivars and Those from the GenBank
Authors: Zhao Yongying , Zhao Xianlin , Xiang Zhiguo , Zhang Dan , Zhang Yuyang , Wang Meifang , Yang Hongshan 
Published: October 2022

Abstract
Background: Barley prolamin is a protein affecting end-use quality, malt production, and feeding value. Barley B-hordeins account for 70-80% of total prolamins and have significant effects on barley quality. It is of great importance to study genes encoding B-hordeins.
Methods: Eighteen different barley varieties were used to identify new B-hordein genes. Genomic DNA was extracted from barley seedlings using a modified CTAB procedure, and PCRs were performed to amplify B-hordein genes using newly designed primers based on the previously published B-hordein gene sequences (Accessions X03103 and X87232). The B-hordein genes registered in GenBank were also obtained from NCBI. Gene sequences were analyzed using the software DNAman. Phylogenetic analysis was conducted by the method of Maximum Likelihood.
Results: A total of 20 complete B-hordein gene sequences were obtained, including 14 putative active genes and 6 pseudogenes. Sequence variations were identified in all 20 genes compared with 72 B-hordein genes from GenBank (including 27 genes we previously identified). The deduced amino-acid sequences of 13 genes had a typical set of 8 conserved cysteine residues, and the other one had 7 cysteines and this gene may have positive effects on barley quality. Sequence analysis and phylogenetic analysis indicated obvious differences between the three kinds of B-hordeins ended with an amino acid V, H or Y.
Conclusion: 20 new B-hordein gene sequences were identified, including one with 7 cysteine residues. 92 B-hordein genes were classified into three types (V-type, H-type and Y-type), of which the V-type should be the dominant, original B-hordein genes, while the H-type and the Y-type might be the variants of the V-type. The results provided a reference for further characterizing the B-hordein genes and for breeding quality barley varieties.
Study on biodegradation of polyethylene by microorganisms isolated from Zhanjiang Mangrove Reserve
Authors: Song Qing-Lang , Chen Meng-Meng , Nie Fang-Hong , Zhang Min , Hu Yao , Wei Yun-Li , Lv Guang-Zhou , Wei Wan , Kang Dan-Ju , Chen Zhi-Bao , Lin Hong-Ying , Chen Jin-Jun 
Published: October 2022

Abstract
Zhanjiang Gaoqiao Mangrove Reserve is one of the largest mangrove reserves in China, and its unique ecosystem makes the mangrove rich in microbial resources. In this study, the sediments from Zhanjiang Gaoqiao Mangrove was used as the samples, and polyethylene (PE) was used as the sole carbon source in the carbon-free medium. The microorganisms in the mangrove sediment were enriched, isolated, purified to obtain PE-degradable bacteria; The species of PE-degrading bacteria were determined by morphological analysis, biochemical identification and molecular identification; The degradation ability of the strain to PE was evaluated by weight loss rate and Fourier transform infrared spectroscopy (FTIR). The obtained results presented three strains of pseudo-degradable bacteria S1-1, S1-2 and S1-3, which belonged to Pseudomonas aeruginosa, Acinetobucter venetianus and Klebsiella pneumoniae, respectively. Among them, S1-3 had the best degradation effect, and the weight loss rate reached 4.25% after 120 days. The weight loss rates of S1-1 and S1-2 were 3.81% and 3.88%, respectively. Under the observation of FTIR, it was found that all three strains could change the internal structure of PE. This study laid a foundation for the verification of PE degradation and provided a reference for the bioremediation of PE pollution in the environment.
ReaxFF molecular dynamic simulations on thermal decomposition of RDX based CMDB propellants
Authors: Wei Huanan , Li Tianpeng , Yao Kai , Xuan Zhaolong 
Published: October 2022

Abstract
ReaxFF molecular dynamics (ReaxFF MD) simulations were performed to study the thermal decomposition property of cyclotrimethylenetrinitramine (RDX) based composite modified double base (CMDB) propellants. The intermediate products and final products of the decomposition of RDX based CMDB propellants at 2000 K, 2500 K and 3000 K are obtained. The simulation results show that the decomposition of RDX and RDX/HTPB/Al are primary triggered by N-NO2 rupture, and then, the intermedia products undergo a series of complex interactions to form final products. The final products of RDX/HTPB/Al are H2 and N2, while the final products of pure RDX are H2, N2 and H2O. In addition, the abundance of the main intermediate products generated by RDX/HTPB/Al is lower than that of RDX, in that the reaction between intermediate products is more complex for RDX/HTPB/Al. Moreover, the decomposition rate of RDX/HTPB/Al increases with the increasing temperature.
Optimization of Multi Hop Data Aggregation in Medical Iot Using Trust Based Secure Routing
Authors: A Sunithanandhini , Natarajan Krishnaraj , J Ramprasath 
Published: October 2022

Abstract
The concept of the Internet of Things (IoT) consists of various sensing devices that have been subject to the threats that stem from an increased dependence on the technologies of communication. The IoT is the concept of healthcare is the main ingredient in the provision of medical facilities to patients and also facilitates both hospitals and doctors. The system proposed contained different medical devices like the sensors and the applications that are mobile-based or web-based. These communicate by means of the devices connected through the network that helps in monitoring and recording medical information and health data of the patients. The IoT was characterized by distributed topology and limited energy. For this scenario, there is a routing algorithm that is energy-saving and secure playing a major role to ensure IoT performance. The aggregation of security data has a crucial role in reducing the transmission of data and further in prolonging the lifetime of Wireless Sensor Network (WSN). When there was a threat to node security, the nodes had generated different data errors resulting in trouble to the measures of security. Owing to the difference in standards and their communication stacks, the traditional mechanisms to security were dependent on the trust management for functioning. For the purpose of this work, there was a multi-hop routing model used in medical IoT that was proposed. For balancing of consumption of energy and trust, routing from the source to the destination has to be taken into consideration for the appraisal of trust as opposed to the destination peers. At the same time, the consumption of energy has to be one major criterion. There was an Imperialist Competitive Algorithm (ICA) with Harmony Search (HS) that can balance the consumption of energy for the reduction of trust cost. This was based on a socio-politically inspired strategy of optimization. The HS was based on the process of improvisation of musicians. The results of the experiment proved this strategy was better in terms of performance than the other methods.