bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trajectory patterns and factors influencing perinatal fatigue among Chinese women from late pregnancy to 6 months after delivery
Authors: Zhu Xiaoxiao , Xia Haiou 
Published: May 2022

Background
Perinatal fatigue among women is related to the clinical outcomes of mothers and infants. Perinatal fatigue changes over time, and the trajectory varies according to the predictors and outcomes of the mothers. This, however, has not been documented in any study.

Objectives
This study aimed to identify and characterize the trajectory patterns of perinatal fatigue among women from late pregnancy to 6 months after delivery.

Methods
We used growth mixture modeling to estimate the trajectory of perinatal fatigue at 28 gestational weeks (T0), 37 gestational weeks (T1), 3 days (T2), 1 week (T3), 6 weeks (T4), and 6 months (T5) after delivery with (n = 1,030). The Mann-Whitney U test and binary logistic regression were used to tie the selected trajectory classes to predictors and outcomes.

Results
There were two distinct patterns of perinatal fatigue in women: “persistently high” (11.1%, n = 114) and “persistently low” (88.9%, n = 916). Levels of perinatal fatigue among women in the “persistently high” group were higher than those in the “persistently low” group across the six measurements. Complications, fatigue at T0, and employment status in late pregnancy were all significant predictors of trajectories. Additionally, the “persistently high” group had a greater prevalence of difficult baby care and weight retention and a lower prevalence of exclusive breastfeeding.

Conclusions
Our study proved the heterogeneity and characteristics of perinatal fatigue among women. Future research should concentrate on developing intervention packages targeted at specific individuals in order to alleviate perinatal fatigue in women.
Impact of Social Media on Student’s Academic Preparation of the Government Business College in Bhutan: The Students’ Insight
Authors: Sharma Dhanapati , Lhamo Sonam , Wangmo Sangay , Choden Sangay , Mongar Sher Bdr , Selden Meto 
Published: May 2022

Aim: This study was carried out to explore the impact of social media from the students’ perspective.
Methodology: 318 quantitative-based questionnaires were distributed to the first-year students, second-year students, and final-year students of Gedu College of Business Studies, the only government business college in Bhutan. The students were asked to rate on the Likert scale to determine how social media assisted them in academic preparations. The students also rated the challenges faced while using social media and for what other purposes social media was used besides academic preparation. Descriptive statistics was used to draw results.
Results: The study found out that there was a positive impact of social media on students. It was mainly used to hold discussions with peers for exam preparations, research purposes, interaction with teachers, and solving academic problems. Students also used social media as a platform for socialization and entertainment purposes. Despite the positive effects of social media, students also faced some restrictions to access social media. Thus, the use of social media assisted the students in their academic preparation.
Conclusion: The study revealed that the use of social media helps student in their academic preparation providing the facility to communicate and converse with their friends and teachers to prepare for exams and enhancing collaborative learning.
Hysteresis modulation‐based sliding mode load frequency controller for multi‐area power system
Authors: Mahendran Mahesh Veluchamy , Vijayan Velappan 
Published: May 2022

AbstractRecently the raise in interconnection of the power system leads to vigorous change of power flow, as well as load in tie‐line. Hence, there is a need of robust control in both tie‐line power flows and systems frequency. This research work aims to design a dual‐mode switch controller‐based load frequency control in multi‐area interconnected power system (MAIPS). In this, the incremental control action's influence is taken along with the constraints of the system dynamic such as Governor with Dead Band, Capacitive Energy Storage, and Generation Rate Constraint. This work on the proposed controller of the multisource‐MAIPS (MS‐MAIPS) is operated on the basis of dual mode switching function. For this purpose, a threshold value is evolved. The control on MPC and optimized hysteresis modulation based sliding mode control (HMSMC) is varied according to this switching function. For attaining the fascinating performance, the optimal tuning of switch threshold and the gain of HMSMC controller is exploited by a new Self‐Adaptive Sea Lion algorithm. To the end, variation of control parameters like , , , as well as for reducing unwanted variances in power flows among control areas is used to verify the effectiveness of the implemented scheme.
Evaluation of Entropy‐Stabilized (Mg0.2Co0.2Ni0.2Cu0.2Zn0.2)O Oxides Produced via Solvothermal Method or Electrospinning as Anodes in Lithium‐Ion Batteries
Authors: Triolo Claudia , Xu Wenlei , Petrovičovà Beatrix , Pinna Nicola , Santangelo Saveria 
Published: May 2022

AbstractEntropy‐stabilized oxides (ESOs), such as (Mg0.2Co0.2Ni0.2Cu0.2Zn0.2)O, have recently gained significant interest as novel anodes for lithium‐ion batteries (LIBs) due to their stable crystal structure and robust lithium‐storage properties. In this work, (Mg0.2Co0.2Ni0.2Cu0.2Zn0.2)O oxides with different morphologies are prepared by electrospinning and solvothermal method and are applied as anode active materials for LIBs. It is found that different morphologies possess different characteristics, namely particle size, particle size range, and defect density, which have a significant effect on the electrochemical behavior. The most active (Mg, Co, Ni, Cu, Zn) ESO shows outstanding electrochemical properties in terms of high reversible capacity (480 mAh g–1 at 20 mA g–1), superior rate capability (206 mAh g–1 at 2 A g–1), and excellent cycling stability (390 mAh g–1 at 500 mA g–1 after 300 cycles). The strategy demonstrates the importance of engineering microstructures in tailoring the electrochemical performance.
Scalable Manufacturing of Liquid Metal Circuits
Authors: Ozutemiz Kadri Bugra , Majidi Carmel , Ozdoganlar O Burak 
Published: May 2022

AbstractLiquid‐metal (LM)‐based soft and stretchable electronics (SSEs) provide unique advantages for wearable computing, soft robotics, and implantable devices applications involving physical interaction with biological tissues and delicate objects. However, the lack of scalable manufacturing techniques prevents their mainstream adoption and commercialization. This paper introduces a scalable and reproducible manufacturing technique for wafer‐level fabrication of LM‐based SSEs, including LM‐only devices and hybrid circuits with LM and solid‐state microelectronics. The approach combines selective metal‐alloy wetting (SMAW) and controlled dip‐coating of eutectic gallium‐indium (EGaIn). The alloying of EGaIn and metal enables depositing EGaIn selectively onto the circuit layout defined by lithographically patterned copper traces on elastomer‐coated wafers. An automated, wafer‐level dip‐coating (DC) approach is developed to enable controllable and reproducible deposition of EGaIn. Wafer‐level simultaneous fabrication of many LM capacitors is demonstrated, and their geometric and electrical reproducibility is evaluated. The results indicate that the SMAW‐DC process can fabricate LM circuits reproducibly and rapidly. Hybrid SSEs are demonstrated by fabricating multiple wearable patches of ultra‐high frequency circuits with an LM dipole antenna, an LM strain gauge, and a solid‐state temperature sensor. Importantly, the presented technique can be integrated into the standard microfabrication flow for microelectronics, ensuring a high level of scalability.
Donor–Acceptor–Donor “Hot Exciton” Triads for High Reverse Intersystem Crossing in OLEDs
Authors: Zhu Yanan , Vela Sergi , Meng Hong , Corminboeuf Clémence , Fumanal Maria 
Published: May 2022

AbstractHot exciton materials have the potential to improve the quantum efficiency of organic light‐emitting diodes (OLEDs) by promoting high reversed intersystem crossing (hRISC) between a high‐lying triplet (Tn, n ≥ 2) and a radiative singlet (Sm). In recent years, donor–acceptor–donor (D–A–D) molecular systems have shown great promise in its ability to enhance the hRISC process under certain conditions. However, strategies to find appropriate D–A–D combinations beyond trial‐and‐error are still elusive. This work exposes the limited applicability of the current fragment‐based design rules and proposes high‐throughput screening as the optimal route to find candidates that fulfill the energy criteria for hRISC. The strategy consists of first establishing the thresholds for large triplet–triplet splitting and small singlet–triplet gap, then filtering combinations through rate comparison of competitive crossing pathways, and finally confirming hRISC with spin‐orbital coupling evaluation. Based on a dataset of 234 compounds, this protocol identifies 31 candidates with potential for hRISC, 4 of which are reported in the literature. Remarkably, while most of the promising systems show prominent hybridized local and charge transfer character, several candidates do not fulfill this condition, indicating that different routes are possible to design efficient OLED materials.
Ylide‐Functionalized Diisopropyl Phosphine (prYPhos): A Ligand for Selective Suzuki‐Miyaura Couplings of Aryl Chlorides
Authors: Wei Xiao‐Jing , Xue Bingxiang , Handelmann Jens , Hu Zhiyong , Darmandeh Heidar , Gessner Viktoria H. , Gooßen Lukas J. 
Published: May 2022

AbstractThe ylide‐functionalized diisopropyl phosphine (prYPhos) promotes Pd‐catalyzed Suzuki‐Miyaura couplings of aryl chlorides and bromides with arylboronic acids. Using Pd2(dba)3/prYPhos as the catalyst and K2CO3 as the base, various (hetero)biaryls were synthesized in 45–98% yields at mild reaction conditions, tolerating sensitive functional groups and steric hindrance. The electron rich, sterically demanding ligand induces a high selectivity for halides versus triflate. Chloroaryl triflates were selectively coupled at the chloride, leaving inherently more reactive triflate groups in place.magnified image
Hepatocyte Deletion of IGF2 Prevents DNA Damage and Tumor Formation in Hepatocellular Carcinoma
Authors: Kumar Deepak , Das Manasi , Oberg Alexis , Sahoo Debashis , Wu Panyisha , Sauceda Consuelo , Jih Lily , Ellies Lesley G. , Langiewicz Magda T. , Sen Supriya , Webster Nicholas J. G. 
Published: May 2022

AbstractHepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Serine‐arginine rich splicing factor 3 (SRSF3) plays a critical role in hepatocyte function and its loss in mice promotes chronic liver damage and leads to HCC. Hepatocyte‐specific SRSF3 knockout mice (SKO mice) also overexpress insulin‐like growth factor 2 (IGF2). In the present study, double deletion of Igf2 and Srsf3 (DKO mice) prevents hepatic fibrosis and inflammation, and completely prevents tumor formation, and is associated with decreased proliferation, apoptosis and DNA damage, and restored DNA repair enzyme expression. This is confirmed in vitro, where IGF2 treatment of HepG2 hepatoma cells decreases DNA repair enzyme expression and causes DNA damage. Tumors from the SKO mice also show mutational signatures consistent with homologous recombination and mismatch repair defects. Analysis of frozen human samples shows that SRSF3 protein is decreased sixfold in HCC compared to normal liver tissue but SRSF3 mRNA is increased. Looking at public TCGA data, HCC patients having high SRSF3 mRNA expression show poor survival, as do patients with alterations in known SRSF3‐dependent splicing events. The results indicate that IGF2 overexpression in conjunction with reduced SRSF3 splicing activity could be a major cause of DNA damage and driver of liver cancer.
Activation of the Lateral Habenula‐Ventral Tegmental Area Neural Circuit Contributes to Postoperative Cognitive Dysfunction in Mice
Authors: Xin Juan , Shan Weiran , Li Jun , Yu Hai , Zuo Zhiyi 
Published: May 2022

AbstractPostoperative cognitive dysfunction (POCD) is common and is associated with poor outcome. Neural circuit involvement in POCD is unknown. Lateral habenula (LHb) that regulates coping and depression‐like behaviors after aversive stimuli is activated by surgery in the previous study. Here, surgery activated LHb and ventral tegmental area (VTA) are presented. VTA is known to receive projections from LHb and project to the prefrontal cortex and hippocampus. Direct chemogenetic inhibition of LHb or damaging LHb attenuates surgery‐induced learning and memory impairment, N‐methyl‐d‐aspartate (NMDA) receptor activation, endoplasmic reticulum stress, inflammatory responses and cell injury in the VTA, and activation of rostromedial tegmental nucleus, an intermediate station to connect LHb with VTA. LHb inhibition preserves dendritic spine density in the prefrontal cortex and hippocampus. Retrograde inhibition of LHb via its projections to VTA attenuated surgery‐induced learning and memory dysfunction is observed. Retrograde activation of LHb induced learning and memory dysfunction is observed. Inhibition of NMDA receptors, dopamine synthesis, and endoplasmic reticulum stress in the VTA reduced surgery‐induced learning and memory impairment, inflammatory responses, and cell injury are observed. These results suggest that surgery activates the LHb‐VTA neural circuit, which contributes to POCD and neuropathological changes in the brain. These novel findings represent initial evidence for neural circuit involvement in surgery effects.
From Transistors to Phototransistors by Tailoring the Polymer Stacking
Authors: Cui Shuaiwei , Liang Dongxu , Liu Maning , Vivo Paola , Zheng Meng , Zhuang Tao , Sun Qikun , Yang Wenjun , Zhang Haichang 
Published: May 2022

AbstractIt is universally acknowledged that highly photosensitive transistors are strongly dependent on the high carrier mobility of polymer‐based semiconductors. However, the polymer π–π stacking and aggregation, required to increase the charge mobility, conversely inhibit the dissociation of photogenerated charge carriers, in turn accelerating the geminate recombination of electron‐hole pairs. To explore the effects of charge mobility and polymer stacking on the photoresponsivity of the phototransistors, here, two alternating copolymers are synthesized, namely P‐PPAB‐IDT and P‐PPAB‐BDT, by palladium‐catalyzed Stille coupling of PPAB with indaceodithiophene (IDT) or benzo[1,2‐b:4,5‐b′]dithiophene‐2,6‐diyl) (BDT) monomers. The polymer P‐PPAB‐IDT demonstrates a nearly 20 times enhancement in the hole mobility compared to P‐PPAB‐BDT. Yet, P‐PPAB‐IDT surprisingly shows no response to white light illumination, whereas P‐PPAB‐BDT exhibits a significant photoresponse to the same light source with a high light‐current/dark‐current (Ilight/Idark) ratio of 21.6 in the p‐type area and a low current ratio of just 5.2 in the n‐type area. It is believed that this work will provide an effective strategy to develop highly photosensitive polymer semiconductors by reducing polymer stacking and aggregation rather than improving the charge carrier mobility.
Spin‐ and Stress‐Depending Electrical Transport in Nanoparticle Supercrystals: Sensing Elastic Properties of Organic Tunnel Barriers via Tunneling Magnetoresistance
Authors: Dreyer Axel , Rempel Thomas , Gottschalk Martin , Zierold Robert , Weimer Agnes , Feld Artur , Schneider Gerold A. , Weller Horst , Hütten Andreas 
Published: May 2022

AbstractThe spin‐dependent electrical transport in rigid inorganic‐inorganic layered systems is extensively applied for the detection of magnetic fields in data storage. In this work, spin‐dependent electrical transport in flexible organic‐inorganic supercrystals based on superparamagnetic iron oxide nanoparticles is investigated. These nanoparticles are stabilized by oleic acid ligands, which in turn are serving as tunneling barriers between individual magnetic nanoparticles. The resulting tunneling magnetoresistance (TMR) is tunable due to the elastic properties of these organic barriers. Applying external mechanical stress on this composite material will change the average distance between adjacent nanoparticles and will hence determine the resulting TMR‐effect amplitude. Thus, measured stress‐induced changes in the barrier thickness at sub‐nanometer scale allow for determining the mechanical properties of organic barrier molecules in the confined space between the particles. These results provide the foundation for a new type of mechanical sensor.
Formation of viscoelastic droplets in a step‐emulsification microdevice
Authors: Liu Xiyang , Jiang Shaokun , Zhu Chunying , Ma Youguang , Fu Taotao 
Published: May 2022

AbstractIn this article, polyethylene oxide glycerin aqueous solution is used as the dispersed phase, and cyclohexane is used as the continuous phase to study the formation mechanism of viscoelastic fluid droplets in a step‐emulsification microdevice. The formation process of viscoelastic droplets mainly includes three stages: two‐dimensional expansion stage, necking stage, and pinch‐off stage. The elasticity has basically no effect on the two‐dimensional expansion stage, but it can delay the process of the necking stage and cause the beading phenomenon of droplets in the pinch‐off stage. The results show that the effect of elasticity on the droplet size is weak, but it cannot be ignored. Moreover, the elasticity will be coupled with the viscous force to reduce the operating range of the dripping regime. Finally, the influence of the elasticity on the formation of satellite droplets is analyzed, and the method to prevent the influence of satellite droplets is proposed.
Mentoring in Times of Crisis and Beyond
Authors: Halabi Nabil M. , Milić Jovana V. , Kaafarani Bilal R. 
Published: May 2022

AbstractDuring the global crisis triggered by the COVID‐19 pandemic, university programs, meetings, and conferences have moved to virtual settings, with consequent erosion of mentorship opportunities for students and early‐career professionals. This calls for mentorship platforms that are adapted to the new landscape in order to bring about a positive change. Our Viewpoint Article shares the perspective of the Transformative Education program and Mentorship Talks initiative at the American University of Beirut in Lebanon, with the aim of providing insights that could stimulate other mentorship platforms.
Synthesis of Si‐Stereogenic Silanols by Catalytic Asymmetric Hydrolytic Oxidation
Authors: Yuan Wei , Zhu Xujiang , Xu Yankun , He Chuan 
Published: May 2022

AbstractDespite growing progress in the construction of chiral organosilicon compounds, the catalytic asymmetric synthesis of silicon‐stereogenic silanols is less explored and remains a considerable challenge. Herein, we report the first enantioselective construction of silicon‐stereogenic silanols by the catalytic asymmetric hydrolytic oxidation of dihydrosilanes. This practical procedure features ambient reaction conditions, high atom economy, good functional‐group compatibility, and H2as the only by‐product, and produces a wide range of valuable chiral silanols and bis‐silanols in decent yields with excellent chemo‐ and stereoselectivity.
A Modular Approach for Diversity‐Oriented Synthesis of 1,3‐trans‐Disubstituted Tetrahydroisoquinolines: Seven‐Step Asymmetric Synthesis of Michellamines B and C
Authors: Bai Miao , Jia Shihu , Zhang Jingyang , Cheng Hong‐Gang , Cong Hengjiang , Liu Shanshan , Huang Zhiqian , Huang Yaoguo , Chen Xiaoming , Zhou Qianghui 
Published: May 2022

Abstract1,3‐trans‐Disubstituted tetrahydroisoquinoline (THIQ) is a common heterocyclic structural unit of naphthylisoquinoline alkaloids. The assembly of this structural unit is not trivial, which constitutes a substantial challenge in the total synthesis of naphthylisoquinoline alkaloids and related pharmaceuticals. Herein, we report a modular and convergent method for the rapid assembly of 1,3‐trans‐disubstituted THIQ frameworks through a three‐component Catellani reaction and a AuI‐catalyzed cyclization/reduction cascade. With widely available simple aryl iodides, aziridines and (triisopropylsilyl)acetylene as the building blocks, this method paves a practical way for the diversity‐oriented synthesis of 1,3‐trans‐disubstituted THIQs. Based on this new method, concise syntheses of an analogue of the new drug mevidalen and four naphthylisoquinoline alkaloids have been accomplished, demonstrating the broad synthetic utility of this approach.
Guest‐Modulated Circularly Polarized Luminescence by Ligand‐to‐Ligand Chirality Transfer in Heteroleptic PdII Coordination Cages
Authors: Wu Kai , Tessarolo Jacopo , Baksi Ananya , Clever Guido H. 
Published: May 2022

AbstractMulticomponent metallo‐supramolecular assembly allows the rational combination of different building blocks. Discrete multifunctional hosts with an accessible cavity can be prepared in a non‐statistical fashion. We employ our shape‐complementary assembly (SCA) method to achieve for the first time integrative self‐sorting of heteroleptic PdII cages showing guest‐tunable circularly polarized luminescence (CPL). An enantiopure helicene‐based ligand (M or P configuration) is coupled with a non‐chiral emissive fluorenone‐based ligand (A or B) to form a series of Pd2L2L′2 assemblies. The modular strategy allows to impart the chiral information of the helicenes to the overall supramolecular system, resulting in CPL from the non‐chiral component. Guest binding results in a 4‐fold increase of CPL intensity. The principle offers potential to generate libraries of multifunctional materials with applications in molecular recognition, enantioselective photo‐redox catalysis and information processing.
Synthesis and Characterization of Spent Bleaching Clay‐based Geopolymer: An Effort towards Palm Oil Industry Waste Reutilization
Authors: Ying Mak Wei , Azmi Mastura , Ganesan Shangeetha 
Published: May 2022

AbstractSpent bleaching clay (SBC) is a problematic waste from the palm oil industry with worldwide availability. In this study, geopolymer was synthesized from SBC, a kind of aluminosilicate material with an alkaline activator solution that is made up of sodium hydroxide and sodium silicate. Calcium silicate (CS), which is a by‐product of the silicates removal from wastewater, was also added to the formulation. The geopolymer mixture paste was cured in an oven at 80 °C for 24 h and at room temperature for 7 days. The characterizations were carried out using FTIR spectroscopy, SEM/EDX, TGA, BET, and XRD. The SEM images showed an aggregate of aluminosilicate material is formed with some unreacted particles on the surface of the geopolymer. The TGA results show that the geopolymers decomposed at a higher temperature than SBC, demonstrating its heat resistance properties. The BET results showed the addition of CS formed a denser geopolymer with a total pore volume of 0.0636 cm3/g.