bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recycled carbonates in the mantle sources of natural kamafugites: A zinc isotope perspective
Authors: Ma Lei , Liu Sheng-Ao , Zhao Zhidan , Yu Xue-Hui 
Published: June 2022

Abstract
Kamafugites are strongly silica-undersaturated melts that are difficult to produce by partial melting of volatile-free peridotites but can be produced experimentally in the presence of CO2. Nevertheless, there is not yet direct evidence for a CO2-rich mantle source and the possible presence of recycled carbonates in the source of natural kamafugites. Marine carbonates have a heavier zinc isotopic composition (δ66Zn) than that of the mantle by up to 1.0‰, making zinc isotopes a sensitive tracer for recycled carbonates in the sources of mantle-derived magmas. Here we take Cenozoic kamafugites from the West Qinling orogen in China as an example to address the origin of this rare volcanic rock. The West Qinling kamafugites are strongly silica-undersaturated (SiO2 = 37.0 to 43.0 wt%) and have significantly higher δ66Zn (0.30‰ to 0.47‰) than that of the normal mantle (0.18 ± 0.05‰). No correlation between δ66Zn and MgO or SiO2 contents is observed, indicating that the high δ66Zn was not a result of magmatic differentiation. Modeling of melting indicates that even at extremely low degree (~0.5%), partial melting of a normal peridotitic source is still unlikely to produce silicate melts with δ 66Zn values exceeding 0.30‰. Thus, the elevated δ66Zn of the West Qinling kamafugites demonstrates the presence of recycled carbonates in their mantle sources. Binary-mixing modeling suggests that the source contains ~5 to 15% recycled carbonates, which is supported by the positive correlation between δ66Zn and CaO/Al2O3. Overall, the West Qinling kamafugites represent the products of low-degree partial melting of a recycled carbonate-bearing peridotite source, which provides evidence for an important role of recycled carbonates in the origin of natural kamafugite suites.
Groundwater Assessment and Management for sustainable water-supply and coordinated subsurface drainage
Authors: Foster Stephen , Gogu Radu 
Published: June 2022

Abstract
Groundwater beneath cities is important. Water utilities and private abstractors use is it as a secure source of water-supply and municipal authorities have to cope with it when planning sanitation and using underground space for building and transportation infrastructure, but all too often neither have a comprehensive understanding. This Guidebook aims to highlight what water utilities and municipal government can do to improve groundwater assessment, management and monitoring to avoid experiencing ‘nasty surprises’.
Groundwater, especially from deeper aquifers, is a critical resource for enhancing urban water-supply security under climate-change stress. But to achieve its use sustainably will require adaptive promotion of resource management and protection, according to local circumstances. In recent times municipal governments are making much more use of urban subsurface space (especially down to 15-metres depth) for construction. Traditionally the drainage and stability of such structures were achieved by individual site investigation, but today a more coordinated approach is needed to managing shallow groundwater conditions.
The Guidebook is divided into three complementary parts: Part A is intended for guidance of water-utility, together with water-resource agency and municipal sanitation department, staff working to improve urban water-supply resilience, with its inevitable requirement to get more involved in groundwater management. Part B is intended for guidance of municipal government authorities working to improve the design and execution of urban infrastructure to avoid potentially costly subsurface drainage issues, structural instability and groundwater flooding problems. Part C provides a series of case histories on urban groundwater management from around the world.
ISBN: 9781789063103
EISBN: 9781789063110
ePub: 9781789063127
Physio-chemical and heavy metal assessment of groundwater near dumping sites in Srinagar District, Jammu & Kashmir-India
Authors: Hafiz Imran , Singla Sandeep , Hafiz Bisma Zahoor 
Published: June 2022

Abstract
The present study is aimed to analyze and assess the critical quality parameters of ground water in district Srinagar spread over distinct seasons of the year 2020. The analysis was carried out on 15 Physio-Chemical quality parameters and 6 trace element concentrations (Lead, Zinc, Cadmium, Chromium, Nickel & Copper). Primary data was collected from 6 distinct sites of the district and subjected to methodical analysis. It was revealed that the mean values of various physio- chemical parameters are within the prescribed permissible levels while as heavy metal concentrations exhibit an escalating tendency across all selected sites especially GW1 (Pb 329, Cu 86, Ar 61, Zn 191), GW2 (Zn 132) and GW3 (Zn 144, Ar 67). The results indicate that waste disposal mechanism in hospitals of Srinagar is not environmental conducive and there is necessity to prevent further denigration of ground water sources in the region. Not denying that the present work is not the panacea for ground water contamination but the methodology adopted for this study is expected to pave way for further hydro-geological analysis in the region to identify the critical quality issues and also to explore remedial strategy to conserve the qualitative characteristics of ground water in the region.
Direct Monosaccharide Composition And N-Linked Oligosaccharide Analysis of Pvdf-Cartridge Immobilized Glycoproteins
Authors: O'Neill Roger , Somack Ralph , Olechno Joseph D. 
Published: June 2022

Abstract:
PVDF membrane-containing ProSpinncTM and ProSorbTM cartridges, designed for preparation of proteins and pep­ tides for amino acid and sequence analysis, can also be used for glycoprotein sample preparation and carbohy­ drate analysis. These devices concentrate samples from large volumes and remove interfering substances. Com­
position analysis and N-linked oligosaccharide "fingerprint" analysis can be performed directly on the PVDF
membrane, using kits available from Perkin-Elmer.
Monte Carlo analysis of potential C-terminal membrane interactive α-helices
Authors: Pewsey Arthur R. , Phoenix David A. , Roberts Martin G. 
Published: June 2022

Abstract:
Known membrane anchors of four prokaryotic carboxypeptidases were compared to the membrane interactive toxin melittin and an endopeptidase which contains a potential membrane anchor. Existing methodologies based on hydrophobic moment profile analysis have been extended to place them on a more rigorous statistical footing. All four carboxypeptidase anchors were predicted to contain a segment of surface active amphiphilic α-helix and the endopeptidase was predicted to be weakly membrane interactive.
AGAP2-AS1: An Indispensable lncRNA in Tumors
Authors: Wang Bei , Chen Jinlan 
Published: June 2022

Background:
LncRNA has been found to participate in a variety of biological processes
and play an important role in the occurrence and development of tumors. Therefore, it is of vital
clinical value to study the relationship between lncRNA and tumor. It has been confirmed that
lncRNA affects tumor progression through sponge mRNA, regulation of signal pathways and activity
of oncogenes. Recent studies have shown that LncRNA AGAP2-AS1 is closely related to
tumor, because this review focuses on the molecular mechanism of LncRNA AGAP2-AS1 affecting
tumor progression.

Methods:
The role of LncRNAAGAP2-AS1 in tumor was summarized by searching the literature
related to LncRNAAGAP2-AS1 from PubMed in recent years.

Results:
LncRNA AGAP2-AS1 is abnormally expressed as an oncogene in tumors, which participates
in biological processes such as tumor proliferation, migration, invasion and autophagy.
LncRNA AGAP2-AS1 plays an important role in tumorigenesis and development by binding to
mRNA, regulating signal pathway and affecting protein activity, which suggests that AGAP2-
AS1 may play a great potential value in the treatment of human cancer.

Conclusion:
The abnormal expression of LncRNAAGAP2-AS1 plays an important role in the
progression of tumor and has a promising value in the treatment of tumor. Exploring the molecular
mechanism of lncRNA AGAP2-AS1 is of indispensable significance for tumor treatment.
Capecitabine and Hand-foot Syndrome: A Case Report
Authors: Yella Sree Sudha Tanguturi , Uppala Praveen Kumar , Varghese Anjaly Mary , Velmurugan Hemasri , Thangaraju Pugazhenthan , Krishna Sasanka Kota Shesha Brahma Shree 
Published: June 2022

Abstract:
Capecitabine, a prodrug of 5-fluorouracil, is an FDA-approved drug for adjuvant treatment
of colon, metastatic colorectal, and breast cancer. A variety of mucocutaneous adverse effects has been
recognized with capecitabine. The pathogenesis of such manifestations still remains an enigma though
various theories have been proposed. Here, we report two such cases. A 59-year-old female with carcinoma
of the sigmoid colon on palliative therapy developed localized cutaneous hyperpigmentation of
the palms and soles secondary to capecitabine in her 2nd cycle. Another case was of a 42-year-old female
with stomach adenocarcinoma, who developed similar adverse effects after administration of
capecitabine in her 4th cycle. Since these drugs have been widely used in recent years due to their relative
ease in administration, the relative unawareness of Hand-foot syndrome (HFS) caused due to this
drug makes it a prudent topic to be reported.
Participation in Social Group Activities and Risk of Dementia: A Systematic Review
Authors: Taniguchi Rika , Ukawa Shigekazu 
Published: June 2022

Introduction:
This systematic review aimed to assess the association between social participation in group activities or associations and the risk of dementia based on longitudinal cohort studies.

Methods:
We searched the electronic database PubMed for relevant studies in English published up to April 13, 2021. The search strategy included a combination of terms related to (1) longitudinal cohort studies, (2) assessing the association between social participation in group activities or associations and the risk of dementia, and (3) the article must be published in English or Japanese.

Results:
Of the 1,881 identified studies, 7 were included in the current systematic review. Five of these seven studies indicated social participation in group activities or associations to be significantly associated with a decreased risk of dementia. Our search also revealed the following points: 1) four studies evaluated the association between the specific type of social participation and the risk of dementia; 2) two studies evaluated the association between the frequency of social participation and the risk of dementia, and 3) one study investigated the effects of changes in the state of social participation on the risk of dementia.

Conclusion:
To clarify the association between social participation in group activities or associations and the risk of dementia, future studies should: 1) evaluate the association between the specific type and frequency of social participation and the risk of dementia, and 2) investigate the effects of changes in the states of social participation on the risk of dementia.
Microbial Production of Lactic Acid – A Review
Authors: Arshad Hira , Irfan Muhammad , Shakir Hafiz Abdullah , Khan Muhammad , Ali Shaukat , Saeed Shagufta , Franco Marcelo 
Published: June 2022

Abstract:
Lactic acid is a generally existing natural acid, which is significant because of its wide
use in food and food-related ventures, pharmaceutics, the cosmetics sector and its ability to create
biopolymers. Lactic acid is eco-friendly, can be obtained from natural crude substances utilizing
different varieties of microbes, and is chemically synthesized. Taking into account the value of lactic
acid, this is a brief review of methods of processing, applications, microbes and substrates required
for lactic acid production.
HISTORY TOMB OF DATUK ABDURRAHIM BIN ABU BAKAR IN LATENG, BANYUWANGI, EAST JAVA AS A HISTORY LEARNING SOURCE IN BANYUWANGI 1 STATE HIGH SCHOOL
Authors: Asy'ari Faruq Hasan , Ediyono Suryo 
Published: June 2022

Datuk Abdurrahim Bin Abu Bakar is known as a preacher of Islam, namely spreading Islam in various areas, especially Banyuwangi. Every day, the tomb of Datuk Abdurrahim Bin Abu Bakar is never empty of pilgrims who come from various regions with different goals and motivations. The tomb, which is located not far from the city center of Banyuwangi, is very sacred to the people of Banyuwangi. This is very unique, because usually the graves that are sacred to the community are located in forests, hills, and beaches, which are far from residential areas. The further uniqueness of the name of the tomb itself. At the beginning of the name there is the word "datuk", the word comes from the Malay culture which is used to address an old man. If you look at the culture in Banyuwangi, East Java, to call an old man by using the word "mbah". In this research, it can be collected using the historical method with stages; (1) heuristics, (2) source criticism, (3) interpretation, (4) historiography. The purpose of this research is to; (1) Knowing the history of the Tomb of Datuk Abdurrahim Bin Abu Bakar, (2) Knowing the potential of the Tomb of Datuk Abdurrahim Bin Abu Bakar Bin Abdurrahim Bauzir as a source of learning history in high school and the values of character education in compulsory history learning for class X according to the 2013 curriculum, such as; tolerance, religious, honesty, helpful help, hard work, and discipline. It is hoped that further researchers can complement the research results that have been written by current researchers Keywords: Tombs, Character values, History Learning Resources
Sex Workers’ Lived Experiences With COVID-19 on Social Media: Content Analysis of Twitter Posts
Authors: Al-Rawi Ahmed , Zemenchik Kiana 
Published: June 2022

Background
The COVID-19 pandemic has drawn attention to various inequalities in global societies, highlighting discrepancies in terms of safety, accessibility, and overall health. In particular, sex workers are disproportionately at risk due to the nature of their work and the social stigma that comes alongside it.

Objective
This study examines how public social media can be used as a tool of professional and personal expression by sex workers during the COVID-19 pandemic. We aimed to explore an underresearched topic by focusing on sex workers’ experiences with the ongoing COVID-19 pandemic on the social media platform Twitter. In particular, we aimed to find the main issues that sex workers discuss on social media in relation to the COVID-19 pandemic.

Methods
A literature review followed by a qualitative analysis of 1458 (re)tweets from 22 sex worker Twitter accounts was used for this study. The tweets were qualitatively coded by theme through the use of intercoder reliability. Empirical, experimental, and observational studies were included in this review to provide context and support for our findings.

Results
In total, 5 major categories were identified as a result of the content analysis used for this study: concerns (n=542, 37.2%), solicitation (n=336, 23.0%), herd mentality (n=231, 15.8%), humor (n=190, 13.0%), and blame (n=146, 10.0%). The concerns category was the most prominent category, which could be due to its multifaceted nature of including individual concerns, health issues, concerns for essential workers and businesses, as well as concerns about inequalities or intersectionality. When using gender as a control factor, the majority of the results were not noteworthy, save for the blame category, in which sexual and gender minorities (SGMs) were more likely to post content.

Conclusions
Though there has been an increase in the literature related to the experiences of sex workers, this paper recommends that future studies could benefit from further examining these 5 major categories through mixed methods research. Examining this phenomenon could recognize the challenges unique to this working community during the COVID-19 pandemic and potentially reduce the widespread stigma associated with sex work in general.
Exploring a Need for a Cardiometabolic Disease Staging System as a Computerized Clinical Decision Support Tool: Qualitative Study
Authors: Karabukayeva Aizhan , Anderson Jami L , Hall Allyson G , Feldman Sue S , Mehta Tapan 
Published: June 2022

Background
Although cardiometabolic diseases are leading causes of morbidity and mortality in the United States, computerized tools for risk assessment of cardiometabolic disease are rarely integral components of primary care practice. Embedding cardiometabolic disease staging systems (CMDS) into computerized clinical decision support systems (CDSS) may assist with identifying and treating patients at greatest risk for developing cardiometabolic disease.

Objective
This study aimed to explore the current approach to medical management of obesity and the need for CMDS designed to aid medical management of people living with obesity, at risk of being obese, or diabetic at the point of care.

Methods
Using a general inductive approach, this qualitative research study was guided by an interpretive epistemology. The method included semistructured, in-depth interviews with primary care providers (PCPs) from university-based community health clinics. The literature informed the interview protocol and included questions on PCPs’ experiences and the need for a tool to improve their ability to manage and prevent complications from overweight and obesity.

Results
PCPs (N=10) described their current approaches and emphasized behavioral treatments consisting of combined diet, physical activity, and behavior therapy as the first line of treatment for people who were overweight or obese. Results suggest that beneficial features of CDSS include (1) clinically relevant and customizable support, (2) provision of a comprehensive medical summary with trends, (3) availability of patient education materials and community resources, and (4) simplicity and ease of navigation.

Conclusions
Implementation of a CMDS via a CDSS could enable PCPs to conduct comprehensive cardiometabolic disease risk assessments, supporting clinical management of overweight, obesity, and diabetes. Results from this study provide unique insights to developers and researchers by identifying areas for design optimization, improved end user experience, and successful adoption of the CDSS.
Metodología para la orientación de inclusión laboral, productiva y de empredimiento de la población “pimpinera” de Ipiales, Pupiales y Gualmatán
Authors: Gómez Rosero Álvaro Hugo , Gómez Achicanoy Germán Alfredo , Dorado Goyes Jorge Arturo 
Published: June 2022

La organización Internacional del Trabajo OIT en convenio con la Universidad Mariana presenta la metodología para orientar la línea de Inclusión laboral y Productiva empresarial de 140 personas como muestra de la población de “Pimpineros” en los municipios de la Frontera con el Ecuador y Colombia, zona andina, Ipiales, Gualmatán y Pupiales.
De esta manera, el proyecto se centró en el diagnóstico y formulación de las acciones para promover la transición de la economía informal a la formal de aquellas personas que se dedican a la distribución de combustible sin los requisitos legales. La población caracterizada mostró interés en el proceso investigativo con expectativa de reconversión laboral, trabajo en comunidad con apoyo de instituciones que faciliten la participación en políticas que estén orientadas al logro de la equidad y la inclusión. Lo anterior, a través del desarrollo de actividades orientadas a la realización de una investigación sobre la población “Pimpinera” a partir de, entre otros ejercicios, la articulación con entidades territoriales y la convocatoria para la focalización en la población que se dedica a la distribución de combustibles líquidos sin observancia de las normas legales.
Upaya Peningkatan Perilaku Ibu Postpartum Melalui Edukasi Family Centered Maternity Care (Fcmc) Tentang Perawatan Masa Postpartum di Wilayah Kerja Puskesmas Gambirsari Surakarta
Authors: Widyastutik Desy , Ernawati Ernawati , Pratiwi Erinda Nur , Wulandari Retno 
Published: June 2022

The role of a parent cannot be separated from the participation or cooperation between the mother and the family (husband) and other family members. Barriers that are still found in the care of postpartum mothers are the perception of the community that post partum mothers are sick mothers, their mobility is inhibited, their diet is restricted, colostrum breastfeeding is inhibited so that the needs of post partum mothers are prioritized for full rest. The involvement of extended families in infant care has so far been misunderstood, where baby care is left to other family members.
After efforts to improve the behavior of postpartum mothers through Family Centered Maternity Care (FCMC) education, it is hoped that postpartum mothers can carry out postpartum care by involving their families. Implementation method with demonstration and discussion. The media used are baby phantoms, postpartum care booklets, LCDs, laptops and projectors. The implementation of health education is carried out by home visits by paying attention to health protocols from March 2020 to September 2020.
The result of community service is that 90% of postpartum mothers can provide postpartum care with family involvement. And from the results of monitoring and evaluation by means of meeting again by means of home care to postpartum mothers using instruments related to postpartum care. Based on the implementation of community service, it can be concluded that there is an increase in the behavior of postpartum mothers in postpartum care in the Gambirsari Public Health Center, Surakarta.
Maternal dietary glycemic index and glycemic load in pregnancy and offspring cord blood DNA methylation
Authors: Küpers Leanne K. , Fernández-Barrés Sílvia , Mancano Giulia , Johnson Laura , Ott Raffael , Vioque Jesus , Colombo Marco , Landgraf Kathrin , Tobi Elmar W. , Körner Antje , Gaillard Romy , Vries Jeanne H.M. de , Jaddoe Vincent W.V. , Vrijheid Martine , Sharp Gemma C. , Felix Janine F. 
Published: June 2022

<p> </p>
<p><strong>Objective</strong>: Suboptimal nutrition in pregnancy is associated with worse offspring cardiometabolic health. DNA methylation may be an underlying mechanism. We meta-analyzed epigenome-wide association studies (EWASs) of maternal dietary glycemic index and load with cord blood DNA methylation.</p>
<p><strong>Research Design and Methods</strong>: We calculated maternal glycemic index and load from food frequency questionnaires, and ran EWASs on cord blood DNA methylation in 2003 mother-offspring pairs from three cohorts. Analyses were additionally stratified by maternal BMI categories. We looked-up the findings in EWASs of maternal glycemic traits and BMI, and in EWASs of birthweight and child BMI. We examined associations with gene expression in child blood in the online Human Early Life Exposome eQTM catalogue and in 223 adipose tissue samples.</p>
<p><strong>Results</strong>: Maternal glycemic index and load were associated with cord blood DNA methylation at 41 cytosine-phosphate-guanine sites (CpGs, P<1.17x10-7), mostly in mothers with overweight/obesity. We did not observe overlap with CpGs associated with maternal glycemic traits, BMI or child birthweight or BMI. Only DNA methylation at cg24458009 and cg23347399 was associated with expression of <em>PCED1B</em> and <em>PCDHG</em>, respectively, in child blood, and DNA methylation at cg27193519 was associated with expression of <em>TFAP4</em>, <em>ZNF500</em>, <em>PPL</em> and <em>ANKS3</em> in child subcutaneous adipose tissue. </p>
<p><strong>Conclusions</strong>: We observed multiple associations of maternal glycemic index and load during pregnancy with cord blood DNA methylation, mostly in mothers with overweight/obesity; some of these CpGs were associated with gene expression. Additional studies are required to further explore functionality, uncover causality, and study pathways to offspring health. </p>