bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perceived overqualification and work engagement: the moderating role of organizational size
Authors: Tomás Inés , González-Romá Vicente , Valls Victor , Hernández Ana 
Published: July 2022

AbstractTesting two competing hypotheses based on different theories (i.e., the theory of career mobility and social exchange theory), this study examines whether organizational size enhances or buffers the negative relationship between perceived overqualification (i.e., having more education or qualifications, skills, and/or experience than one’s job requires) and work engagement (a positive, affective-motivational state of fulfillment characterized by vigor, dedication, and absorption). The study sample consisted of 107 university graduates. A time-lagged design with two data collection points was implemented. Data were analyzed using moderated regression. The results showed that organizational size enhanced the negative relationship between perceived overqualification and engagement (vigor, dedication, and absorption). This is the first study to show the moderator role of organizational size in the investigated relationship. To mitigate the dysfunctional consequences of perceived overqualification on work engagement, we suggest that large organizations should give overqualified employees the opportunity to develop long-term, high-quality relationships in their work environment.
Gasification of Biowaste Based on Validated Computational Simulations: A Circular Economy Model to Handle Poultry Litter Waste
Authors: de Priall Oisín , Brandoni Caterina , Gogulancea Valentina , Jaffar Mohammad , Hewitt Neil J. , Zhang Kai , Huang Ye 
Published: July 2022

AbstractConverting waste biomass resources through downdraft gasification can generate a producer gas for a combined heat and power unit. The study includes feedstock analysis, process modelling using ECLIPSE simulation software, and experimental analysis of materials in a pilot-scale fixed-bed downdraft gasifier. Anaerobic digestate and miscanthus were investigated for comparing the gasification potential of poultry litter as an energy source. Models validated through experimental analysis were applied to a case study based on a typical poultry farm in Northern Ireland.; Results found producer gas with a lower heating value up to 4.15 MJ/Nm3 can be generated. Sufficient poultry waste is generated on-site to produce the required heat and electricity for each shed, allowing the farm to switch from fossil fuels to a local renewable resource and addressing the waste disposal issue.; Downdraft gasification coupled with cogeneration could have a payback period of 4–5 years given the correct conditions. The net present value is positive for all technologies considered (i.e. internal combustion engine and the Organic Rankine cycle combined heat and power unit) under different subsidies, showing the economic viability of the solution. The break-even selling price could be lower than the current grid electricity selling price (£120/MWh) when incentives such as: (i) avoiding disposal cost of £30/tonne, (ii) selling the biochar by-product at £200/tonne and (iii) fuel displacement costs of 1.5p/kWh are considered.
Graphical abstract
Unraveling Heterogeneities in Mindfulness Profiles: a Review and Latent Profile Analysis of the Five Facet Mindfulness Questionnaire Short-Form (FFMQ-SF) in the Spanish Population
Authors: Lecuona Oscar , García-Rubio Carlos , de Rivas Sara , Moreno-Jiménez Jennifer E. , Rodríguez-Carvajal Raquel 
Published: July 2022

Abstract
Objectives
The Five Facet Mindfulness Questionnaire (FFMQ) is one of the most common self-report instruments used in scientific literature to assess mindfulness. However, mixed evidence has been provided regarding its psychometric properties. Among them, the FFMQ seems to present latent classes or profiles with specific patterns in its facets, which might explain said mixed evidence. This study explores mindfulness profiles in the Spanish population using the short form of the FFMQ (FFMQ-SF) and its relations with relevant constructs (i.e., decentering, self-compassion, psychological well-being, psychopathology, positive and negative states).

Methods
A general population sample of 826 participants completed instruments measuring mindfulness and related constructs. Latent profile analyses were applied to the FFMQ-SF facets, and profile membership of participants was estimated for relations with related constructs.

Results
Three latent profiles were found: General Mindfulness, Judgmentally Observing, and Non-judgmentally Aware. General Mindfulness showed expected relations with other constructs, but the other two profiles showed some relations opposite to prior literature: The Judgmentally Observing profile displayed functional behaviors while the Non-judgmentally Aware profile showed an inverse mitigated pattern. Results could not be explained by gender, age, level of studies, or minimum experience with meditation.

Conclusions
Most people (68%) fall into mindfulness profiles that can be regarded as a continuum (e.g., an overall mindfulness factor). However, the FFMQ-SF shows heterogeneities in its facets due to two unique latent profiles, namely “Judgmentally Observing” (7.4%) and “Non-judgmentally Aware” (24.8%). While the structure of these profiles was replicated, relations with relevant psychological constructs contradicted previous literature. Implications and recommendations for future studies are discussed.
Downregulation of PGM5 expression correlates with tumor progression and poor prognosis in human prostate cancer
Authors: Sun Jian , Wang Fei , Zhou Huihui , Zhao Chunchun , Li Kai , Fan Caibin , Wang Jianqing 
Published: July 2022

AbstractProstate cancer (PCa) is the most common malignancy in men in developed countries. Prostate-specific antigen (PSA) remains the most widely used serum marker for prostate cancer. Here, we reported that the expression of phosphoglucomutase-like protein 5 (PGM5) is significantly lower in prostate cancer tissue. The low expression of PGM5 and its related gene signature were found to be linked to poor clinical outcome and high Gleason score. In vitro assays showed that overexpression of PGM5 significantly repressed proliferation and migration of prostate cancer cells. GO and pathway analyses showed the enrichment of genes in regulation of cell growth and migration, and pathways related in cancer. Our additional results showed that the downregulation of PGM5 is closely related to DNA methylation. Taken together, our findings provide the first evidence that PGM5 expression is associated with prostate cancer progression. These results also highlight a preclinical rationale that PGM5 represents a prognostic marker and a promising target for new therapeutic strategies in prostate cancer.
Den Stress im Blick – lokale Blickbewegungsmaße bei der Einschätzung schwierigkeitsgenerierender Merkmale von mathematischen Textaufgaben unter Stress
Authors: Becker Sara , Spinath Birgit , Ditzen Beate , Dörfler Tobias 
Published: July 2022

ZusammenfassungDie Fähigkeit, mathematische Textaufgaben hinsichtlich ihrer schwierigkeitsgenerierenden Merkmale zu beurteilen, erweist sich als wichtiger Indikator der diagnostischen Kompetenz von Mathematiklehrkräften. Die diagnostische Kompetenz umfasst die kognitiven Prozesse der Wahrnehmung von potenziell schwierigkeitsgenerierenden Aufgabenmerkmalen sowie deren Interpretation hinsichtlich ihrer Relevanz. Beide Beurteilungsprozesse erfordern kognitive Kapazitäten, die in realen Lehr-Lern-Situationen aufgrund des kapazitätsreduzierenden Einflusses von Stress beeinträchtigt werden können. Über den Einfluss von Stress auf die Prozesse des Wahrnehmens und Interpretierens von Aufgabenmerkmalen ist bislang wenig bekannt.Vor diesem Hintergrund wurde in der vorliegenden experimentellen Eye Tracking-Studie der Einfluss von Stress auf die diagnostischen Prozesse der Wahrnehmung sowie der Interpretation von schwierigkeitsgenerierenden Merkmalen bei mathematischen Textaufgaben untersucht. Die Teilnehmenden,N = 64 angehende Mathematiklehrkräfte (73,4 % weiblich), wurden randomisiert der Kontrollgruppe oder der Stressgruppe zugeordnet. Die künstliche Erzeugung von Stress bei den Teilnehmenden der Stressgruppe erfolgte vor der Beurteilung der schwierigkeitsgenerierenden Merkmale mithilfe des Sozialevaluativen Kaltwasserstresstests. Der Einfluss von Stress auf die Wahrnehmungsprozesse während des Diagnostizierens wurde über so genannte lokale Blickbewegungsmaße operationalisiert. Der Einfluss von Stress auf die Interpretationsprozesse wurde anhand der Begründungen der Teilnehmenden untersucht.Die Auswertungen der Studie zeigten, dass die schwierigkeitsgenerierenden Textaufgabenmerkmale sowohl von den Teilnehmenden der Kontrollgruppe als auch von denen der Stressgruppe wahrgenommen wurden. Die Aufmerksamkeit unter Stress begrenzte sich jedoch auf potenziell relevante Bereiche der Textaufgaben. Unter Stress wurden insgesamt weniger Merkmale für das diagnostische Urteil herangezogen und jedes schwierigkeitsgenerierende Merkmal wurde weniger oft als relevant interpretiert. Zusammenfassend weisen die Ergebnisse darauf hin, dass angehende Mathematiklehrkräfte unter Stress nur einen selektiven Bereich von Textaufgaben wahrnehmen und verarbeiten können. Insbesondere die kognitiv anspruchsvollen Verarbeitungsprozesse erscheinen eingeschränkt. Dies weist auf eine verzerrte und fehlerhafte Urteilsbildung in Stresssituationen hin.
Allergenicity reduction of the bio-elicited peanut sprout powder (BPSP) and toxicological acceptance of BPSP-supplemented diets assessed with ICR mice
Authors: Weng Brian B.-C. , Liu Yu-Chia , White Brittany L. , Chang Ju-Chun , Davis Jack P. , Hsiao Shih-Hsuan , Chiou Robin Y.-Y. 
Published: July 2022

AbstractThe allergenic and toxicological acceptances of the bio-elicited peanut sprout powder (BPSP) have not been assessed. BPSP was generated from peanut kernels germinated at 26–28 °C for 72 h (designated as 72 h-NGS). The 72 h-NGS were subsequently sliced, incubated, dried, defatted and pulverized to generate bio-elicited peanut sprout powder (BPSP). Protein solubility of BPSP increased 2.6-fold compared to 72 h-NGS. SDS-PAGE analysis revealed BPSP production triggered extensive degradation of the high-molecular weight peanut allergic proteins, mainly Ara h 1 and Ara h 3. Western blotting detected with peanut allergic patients’ IgE indicated decreased in vitro reactivity. Food safety assessment of BPSP was performed with ICR mice fed with basal (control) and three doses of formulated BPSP-supplemented diets containing 0.11 g (normal), 2.5 g (high) and 25 g (super high) BPSP /kg BW. Animals appeared healthy with steady body weight gain in all groups during the entire 35-day dietary intervention. Hematological and serum biochemical analyses revealed no significant difference among groups. Histopathological examination on the tissue sections of primary organs further supported safety with no pathologies. The in vitro allergic reduction and toxicological safety in the BPSP-supplemented dietary intervention in the ICR mice study, support moving forward with BPSP-involved product development.
A new water flooding characteristic curve at ultra-high water cut stage
Authors: Li Shanshan , Feng Qihong , Zhang Xianmin , Yu Chunlei , Huang Yingsong 
Published: July 2022

AbstractA large number of field practices show that the water flooding characteristic curve will appear up-warping phenomenon in ultra-high water cut stage, and the conventional water flooding characteristic curve is difficult to accurately characterize. In this work, a new expression of oil–water relative permeability ratio (Kro/Krw) and water saturation (Sw) is proposed based on the statistical analysis of experimental data of oil–water relative permeability at high displacement multiples. The new expression has a simpler form and fewer unknown parameters. The results show that the expression can accurately fit the later section of the conventional relative permeability ratio curve, and the correlation coefficient is above 0.996. On this basis, a new type of water flooding characteristic curve suitable for the whole process of water flooding reservoir development is established by combining the reservoir engineering method. Numerical simulation and field application show that the new curve has higher accuracy and wider applicability than conventional curve. The prediction error of recoverable reserves calculated by the new curve is only 0.22%, and the error of geological reserves is less than 5%. According to the comparison between the actual data and the predicted data, the actual cumulative oil production is 2.579 × 106 t, the predicted by the new curve is 2.569 × 106 t, the actual ultimate oil recovery is 50.235%, and the predicted is 50.04%. The predicted value is consistent with the actual one. It provides a more reliable method to accurately predict reservoir development indexes and guides the oilfield’s subsequent decision-making.
The Challenge of Catalan Secessionism to the European Model of the Rule of Law
Authors: Hernández Gisela , Closa Carlos 
Published: July 2022

AbstractFar from being an abstract concept, international, European, and Spanish legal orders clearly conceptualize “rule of law”. Catalan secessionism, appealing to the democratic principle, challenged the common understanding of rule of law in the period between 2012 and 2017. This article offers a detailed explanation on how secessionism fundamentally disregarded the common understandings of the rule of law principle and, more precisely, two of its essential elements: the principles of legality and respect for courts. In relation to the former, Catalan separatism assumed competences attributed to the central state, ignored procedural guarantees in passing legislation on the referendum, and adopted ad hoc legal supremacy. In relation to the second, Catalan authorities repeatedly ignored and disobeyed the Spanish Constitutional Court’s rulings. However, disrespect for Constitutional justice turned into an appeal to it when Catalan secessionist leaders sought to defend their individual rights in face of criminal prosecution.
Development, testing, and implementation of a new procedure to assess the clinical added benefit of pharmaceuticals
Authors: Dóczy Veronika , Wernerné Sódar Barbara , Hölgyesi Áron , Merész Gergő , Gaál Péter 
Published: July 2022

Abstract

Objectives
The reimbursement process for innovative health technologies in Hungary lacks any formalized assessment of clinical added benefit (CAB). The aim of this research is to present the development, retrospective testing, and implementation of a local assessment framework for determining the CAB of cancer treatments at the Department of Health Technology Assessment of the National Institute of Pharmacy and Nutrition in Hungary.

Methods
The assessment framework was drafted after screening existing methods and a retrospective comparison of local reimbursement dossiers to that of German and French methods. The Magnitude of Clinical Benefit Scale of the European Society for Medical Oncology was chosen to rate the extent of CAB in oncology, as part of a conclusion complemented by the assessment of endpoint relevance and the quality of evidence. Several rounds of retrospective assessments have been conducted involving all clinical assessors, iterated with semistructured discussions to consolidate divergence between assessors. External stakeholders were consulted to provide feedback on the framework.

Results
Retrospective assessments resulted in average more than 75 percent concordance between assessors on each element of the conclusion. Input from ten stakeholders was also incorporated; stakeholders were generally supportive, and they mostly commented on the concept, the elements of the framework, and its implementation.

Conclusions
The procedure is suitable for routine use in the decision-making process to describe the CAB of antineoplastic technologies in Hungary. Further extension of the framework is required to cover more disease areas for structured and comparable conclusions on CAB of innovative health technologies.
Relic Groundwater and Prolonged Drought Confound Interpretations of Water Sustainability and Lithium Extraction in Arid Lands
Authors: Moran Brendan J. , Boutt David F. , McKnight Sarah V. , Jenckes Jordan , Munk Lee Ann , Corkran Daniel , Kirshen Alexander 
Published: July 2022

AbstractDemand for lithium for batteries is growing rapidly with the global push to decarbonize energy systems. The Salar de Atacama, Chile holds ∼42% of the planet's reserves in the form of brine hosted in massive evaporite aquifers. The mining of these brines and associated freshwater use has raised concerns over the environmental responsibility of lithium extraction, yet large uncertainties remain regarding fundamental aspects of governing hydrological processes in these environments. This incomplete understanding has led to the perpetuation of misconceptions about what constitutes sustainable or renewable water use and therefore what justifies responsible allocation. We present an integrated hydrological assessment using tritium and stable oxygen, and hydrogen isotopes paired with remotely sensed and terrestrial hydroclimate data to define unique sources of water distinguished by residence time, physical characteristics, and connectivity to modern climate. Our results describe the impacts of prolonged drought on surface and groundwaters and demonstrate that nearly all inflow to the basin is composed of water recharged >65 years ago. Still, modern precipitation is critical to sustaining important wetlands around the salar. Recent large rain events have increased surface water and vegetation extents and terrestrial water storage while mining‐related water withdrawals have continued. As we show, poor conceptualizations of these complex hydrological systems have perpetuated the misallocation of water and the misattribution of impacts. These fundamental issues apply to arid regions globally. Our new framework for hydrological assessment in these basins moves beyond calculating gross inputs‐outputs at a steady state to include all compartmentalized stores that constitute “modern” budgets.
Potential of Land‐Neutral Negative Emissions Through Biochar Sequestration
Authors: Werner C. , Lucht W. , Gerten D. , Kammann C. 
Published: July 2022

AbstractNegative emissions (NE) are under discussion as elements of mitigation strategies aiming to achieve the climate targets of the Paris Agreement. However, biomass‐based NE technologies such as bioenergy with carbon capture and storage (BECCS) require vast land areas in order to meet the targets projected by climate economic optimization models, thereby competing with food production and ecosystem protection. Here we assess feasible NE contributions of alternative, more sustainable pyrogenic carbon capture and storage (PyCCS) based on land‐neutral biomass production using biochar‐mediated yield increases to maintain calorie production while realizing net CO2 extraction from the atmosphere. Simulations with a biosphere model indicate that such a land‐ and calorie‐neutral PyCCS approach could sequester 0.44–2.62 Gt CO2 yr−1 depending on the assumed biochar‐mediated yield increase achievable on (sub‐)tropical cropland (15%, 20% and 30%, respectively). Cumulatively, by the end of the century, 33–201 Gt CO2 could be sustainably supplied by such an approach, equaling 6%–35% of the NE demand projected for trajectories likely to limit climate warming to 2°C or lower. Furthermore, additional areas dedicated to BECCS in integrated assessment scenarios could instead be used to increase global calorie production (by 2%–16%), or spared for nature protection (up to ∼ 100 Mha). Thus, land‐ and calorie‐neutral PyCCS may, within limits, contribute to lessening the additional land use pressure of biomass‐based NE technologies.
New Findings From Explainable SYM‐H Forecasting Using Gradient Boosting Machines
Authors: Iong Daniel , Chen Yang , Toth Gabor , Zou Shasha , Pulkkinen Tuija , Ren Jiaen , Camporeale Enrico , Gombosi Tamas 
Published: July 2022

AbstractIn this work, we develop gradient boosting machines (GBMs) for forecasting the SYM‐H index multiple hours ahead using different combinations of solar wind and interplanetary magnetic field (IMF) parameters, derived parameters, and past SYM‐H values. Using Shapley Additive Explanation values to quantify the contributions from each input to predictions of the SYM‐H index from GBMs, we show that our predictions are consistent with physical understanding while also providing insight into the complex relationship between the solar wind and Earth's ring current. In particular, we found that feature contributions vary depending on the storm phase. We also perform a direct comparison between GBMs and neural networks presented in prior publications for forecasting the SYM‐H index by training, validating, and testing them on the same data. We find that the GBMs yield a statistically significant improvement in root mean squared error over the best published black‐box neural network schemes and the Burton equation.
Hydrologic Turnover Matters — Gross Gains and Losses of Six First‐Order Streams Across Contrasting Landscapes and Flow Regimes
Authors: Jähkel A. , Graeber D. , Fleckenstein J. H. , Schmidt C. 
Published: July 2022

AbstractGross gains and losses of stream water and the consequent hydrologic turnover may modify the composition of stream water and drive in‐stream ecological functioning. We evaluated over 500 breakthrough curves of conservative tracer additions to analyze the channel water balance resulting in gross gains and losses, net exchange, and hydrologic turnover. During the hydrological year 2019, seven tracer experiments had been carried out in six first‐order streams along 400 m study reaches. All streams are located in the Holtemme catchment (Central Germany) with three each dominated by forested and agricultural land use. Four of the six streams were characterized by net‐losing conditions. The overall median of gross exchange was five times higher than net exchange. On average, subsurface gains replaced 50% of the original stream water over less than one kilometer of stream length. We even observed cases where over 95% of the stream water turned over within 100 m. Gross exchange was relatively higher in forested than in agricultural streams. Patterns of exchange in the forested streams persisted spatially and were temporally independent of streamflow, whereas in the agricultural ones, variable spatial patterns and streamflow dependence occurred. Overall, moderate flow coincided with highest relative gross exchange. Our results support previous findings that in‐stream solute concentrations could heavily depend on location and magnitude of gains and losses. Gross exchange embodies a permanent but variable control of downstream solute concentrations interacting with the signal of biogeochemical activity. We highlight the importance to include reach‐scale hydrological processes in studies on nutrient spiraling.