bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stock Influence on Growth, Morphological and Biochemical Leaf Parameters Prunus domestica L.
Authors: Motyleva Svetlana , Upadysheva Galina , Tumaeva Tatyana , Kulikov Ivan 
Published: January 2022

Vegetation growth peculiarities and morphological and physical-biochemical features of Prunus domestica L. Utro and Yaichnaya Sinyaya varieties leaves grafted on different growing strength rootstocks were studied. Low-growing clonal rootstocks 140–1 and Novinka decreased the trees growing strength on 15–20% in comparison with strong-growing stocks; medium-growing rootstocks OPA-15-2 and OP-23-23 reduced it on 10%. The longest growing activity and the largest sprouts length was stated on these rootstocks as well, i.e. 1.3–1.4 times more than on other ones. Stable sprouts average length decrease was registered on grafted stocks 140–1 and Novinka. Leaf surface index value on the trees grafted on clonal rootstocks OPA-15-2 and OP-23-23 was on 40% higher than on control, i.e. 4.3 leaves m2/crown projection area m2. Optimal values of total increment, sprouts average length, leaves area and the largest part of physiological-biochemical parameters were stated at medium-growing clonal rootstocks OPA-15-2 and OP-23-23 use. Plum leaves blades were hypostomatic; numerous stomata were located on the abaxial (bottom) side of leaves. Stomata were located in interveinal space irregularly. Stomata length size varied from 14.6 μm (Utro/seedlings) to 22.1 μm (Yaichnaya Sinyaya/OP-23-23). The rootstock has influence on the process of photosynthesis, antioxidant activity, accumulation of minerals and metabolic answerin the leaves.
The effect of subjective sleep latency on BMI of medical interns during and before COVID-19 pandemic
Authors: Bastanhagh Ehsan , Erfanian Reza 
Published: January 2022

Objectives Longer subjective sleep latency and eveningness chronotype are associated with higher BMI. Moreover, COVID-19 lockdown changes have been associated with increased BMI. The aim of this study was to investigate the effect of subjective sleep parameters on BMI of medical interns during and before COVID-19 pandemic.
Material and Methods This cross-sectional study was performed among medical interns. Bedtime, sleep latency, waking time, sleep duration, and reduced morningness-eveningness scores were evaluated.
Results There was significant difference between bedtime before (00:11±50) and during (01:10±85) the pandemic in females (p<0.001). The mean circadian score before and during the pandemic showed significant decrease in females (p=0.011). The correlation between BMI with subjective sleep latency in females before and during the pandemic ((r=0.439, p=0.017), (r=0.422, p=0.014)) was significant.
Conclusion COVID-19 pandemic was associated with a change toward nocturnal life among female medical interns. Subjective sleep latency was significantly correlated with BMI in females.
Compliance to Continuous Positive Airway Pressure therapy in patients with obstructive sleep apnea – long-term assessment
Authors: Pascua Josefina , Blanco Magali , Ernst Glenda , Salvado Alejandro , Borsini Eduardo Enrique 
Published: January 2022

Introduction To assess CPAP acquirement, compliance, and dropout rates among OSA patients three years after the prescription.
Material and Methods We assessed CPAP acquirement (Acq), compliance (Comp), and dropout (Dout) through a telephone survey. We interviewed 156 patients; ESS: 9.9±5.7, AHI>15ev/hour in 96.4%. 92 patients had accessed CPAP therapy (58.9%) and 67 (72.8%) were still using it. Dropout was reported by 25 (27.2%). The Comp group was older (p<0.01), had more men (p<0.001), higher ESS scores (p<0.03) and a higher level of specialist follow-up (p<0.001). Multivariate analysis adjusted showed; follow-up by experts (OR: 4.39; p<0.05) and ESS>10 (OR: 1.25; p<0.05) increased CPAP compliance.
Conclusion There is a high number of patients without CPAP therapy acquirement. Long-term compliance was found in ¾ of the study population in symptomatic patients followed up by specialists. Finally, 43% had effective treatment.
Key genes associated with prognosis and metastasis of clear cell renal cell carcinoma
Authors: Zhong Tingting , Jiang Zeying , Wang Xiangdong , Wang Honglei , Song Meiyi , Chen Wenfang , Yang Shicong 
Published: January 2022

BackgroundClear cell renal cell carcinoma (ccRCC) is a tumor that frequently shows the hematogenous pathway and tends to be resistant to radiotherapy and chemotherapy. However, the exact mechanism of ccRCC metastasis remains unknown.MethodsDifferentially expressed genes (DEGs) of three gene expression profiles (GSE85258,GSE105288andGSE22541) downloaded from the Gene Expression Omnibus (GEO) database were analyzed by GEO2R analysis, and co-expressed DEGs among the datasets were identified using a Venn drawing tool. The co-expressed DEGs were investigated using Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis, and hub genes were determined based on the protein-protein interaction network established by STRING. After survival analysis performed on UALCAN website, possible key genes were selected and verified in ccRCC cell lines and ccRCC tissues (n = 44). Statistical analysis was conducted using GraphPad Prism (Version 8.1.1).ResultsA total of 104 co-expressed DEGs were identified in the three datasets. Pathway analysis revealed that these genes were enriched in the extracellular matrix (ECM)–receptor interaction, protein digestion and absorption and focal adhesion. Survival analysis on 17 hub genes revealed that four key genes with a significant impact on survival: procollagen C-endopeptidase enhancer (PCOLCE), prolyl 4-hydroxylase subunit beta (P4HB), collagen type VI alpha 2 (COL6A2) and collagen type VI alpha 3 (COL6A3). Patients with higher expression of these key genes had worse survival than those with lower expression.In vitroexperiments revealed that the mRNA expression levels ofPCOLCE,P4HBandCOL6A2were three times higher and that ofCOL6A3mRNA was 16 times higher in the metastatic ccRCC cell line Caki-1 than the corresponding primary cell line Caki-2. Immunohistochemistry revealed higher expression of the proteins encoded by these four genes in metastatic ccRCC compared with tumors from the corresponding primary sites, with statistical significance.ConclusionPCOLCE, P4HB, COL6A2 and COL6A3 are upregulated in metastatic ccRCC and might be related to poor prognosis and distant metastases.
Predicting continuous ground reaction forces from accelerometers during uphill and downhill running: a recurrent neural network solution
Authors: Alcantara Ryan S. , Edwards W. Brent , Millet Guillaume Y. , Grabowski Alena M. 
Published: January 2022

Background
Ground reaction forces (GRFs) are important for understanding human movement, but their measurement is generally limited to a laboratory environment. Previous studies have used neural networks to predict GRF waveforms during running from wearable device data, but these predictions are limited to the stance phase of level-ground running. A method of predicting the normal (perpendicular to running surface) GRF waveform using wearable devices across a range of running speeds and slopes could allow researchers and clinicians to predict kinetic and kinematic variables outside the laboratory environment.

Purpose
We sought to develop a recurrent neural network capable of predicting continuous normal (perpendicular to surface) GRFs across a range of running speeds and slopes from accelerometer data.

Methods
Nineteen subjects ran on a force-measuring treadmill at five slopes (0°, ±5°, ±10°) and three speeds (2.5, 3.33, 4.17 m/s) per slope with sacral- and shoe-mounted accelerometers. We then trained a recurrent neural network to predict normal GRF waveforms frame-by-frame. The predicted versus measured GRF waveforms had an average ± SD RMSE of 0.16 ± 0.04 BW and relative RMSE of 6.4 ± 1.5% across all conditions and subjects.

Results
The recurrent neural network predicted continuous normal GRF waveforms across a range of running speeds and slopes with greater accuracy than neural networks implemented in previous studies. This approach may facilitate predictions of biomechanical variables outside the laboratory in near real-time and improves the accuracy of quantifying and monitoring external forces experienced by the body when running.
The Impact of Customer Behavior on E-business during of the COVID-19 Crisis in Jordan
Authors: Muhammad Harith Adnan , Mohammed Ali Ibrahim , Almomani Amer Abdelwali 
Published: January 2022

Aims: This study was conducted to study the impact of customer behavior on e-business in Jordan in light of the increasing spread of the virus.
Study Design: A quantitative research.
Place and Duration of Study: Jordan, between January - September 2020.
Methodology: The Statistical Analysis Software (SPSS) software is used by the researcher. The survey questionnaires framed by the researcher are helping the researcher in representing the data appropriately
Results: The results showed that online purchase was acceptable and high during the Corona pandemic period despite the complete paralysis of movement Before the customer so that there is an alternative in emergency and necessary cases such as the Corona pandemic and the need to take into account the terms and behavior of the consumer when advertising, selling or promoting the commodity on electronic sales platforms.
Conclusion: Through the foregoing according to the data analysis carried out above shows the negative impact on e-business in Jordan due to the Coronavirus (COVID-19) the negative impact created affects sales as well as the purchasing behavior of customers. The business environment in Jordan is seen as weak due to COVID-19. The challenges that retailers in the e-commerce business face is declining customer buying behavior. Also, lower buying behavior reduces bids and shipping as per the surveys carried out this will lead to the deterioration of the e-business as well as huge losses that the e-business will incur. Research questions as well as research objectives set by the researcher a greater impact has been made on the current e-business in the Jordanian market. Buy food products from food stock for this reason. And the hypothesis of the research papers he developed lies a change in food contamination. For this reason, human-to-human contact is restricted which leads to the deterioration of e-commerce sales. Thus the presented analysis supports for this reason a greater impact has been created on the existing e-business in the Jordanian market since there is a concern of the buyer that with Delivery of food products through the electronic company.
Relationship among Continuous Probability Distributions and Interpolation
Authors: Enwere Kelachi P. , Ogoke Uchenna P. 
Published: January 2022

Aims: The Study seeks to determine the relationship that exists among Continuous Probability Distributions and the use of Interpolation Techniques to estimate unavailable but desired value of a given probability distribution.
Study Design: Statistical Probability tables for Normal, Student t, Chi-squared, F and Gamma distributions were used to compare interpolated values with statistical tabulated values. Charts and Tables were used to represent the relationships among the five probability distributions.
Methodology: Linear Interpolation Technique was employed to interpolate unavailable but desired values so as to obtain approximate values from the statistical tables. The data were analyzed for interpolation of unavailable but desired values at 95% a-level from the five continuous probability distribution.
Results: Interpolated values are as close as possible to the exact values and the difference between the exact value and the interpolated value is not pronounced. The table and chart established showed that relationships do exist among the Normal, Student-t, Chi-squared, F and Gamma distributions.
Conclusion: Interpolation techniques can be applied to obtain unavailable but desired information in a data set. Thus, uncertainty found in a data set can be discovered, then analyzed and interpreted to produce desired results. However, understanding of how these probability distributions are related to each other can inform how best these distributions can be used interchangeably by Statisticians and other Researchers who apply statistical methods employed in practical applications.
Efficacy of Herbal Medicine Administration using Neem (Azadirchta indica L) Leaves as Case Study
Authors: Oladejo Duduyemi , Regina Patinvoh , Aisha Adelowo , Akinbomi J. G. 
Published: January 2022

Plants used for treatment of diverse ailments primitively are concocted and used indiscriminately. The efficacy of "Herbal medicine" which is an ancient tradition, used in some parts of Nigeria was investigated to establish herbal applications of Neem (Azadirachta indica) leaves. Neem leaves (Azadirachta indica) was popularly recognised for the treatment of malaria fever. The leaves were plucked at appropriate peak period of the day when oil and moisture contents were recorded maximum. The peak period of contents was found to occurred between 8am-10am on a very sunny days, 10am to 12 on cool days, and 3:00pm to 5:00pm on cloudy days. Aqueous extract from macerated Neem leaves was subjected to qualitative and quantitative analysis. Available phytochemicals evaluated include; saponin (34.89mg/g), tannin (31.715mg/g), flavonoid (31.835mg/g), phenol (43.59mg/g), terpernoid (14.585mg/g), cardiac glycosides (39.335mg/g), steroid (16.185mg/g) and alkaloid (28.76mg/g). These values differ significantly to recommended oral dosage formulation for human consumption: Saponin (1.433ml), Tannin (1.418ml), Flavonoid (13.91ml), Phenol (2.29ml), Terpernoid (8.23ml), Cardiac Glycosides (0.003177ml), Steroid (0.62mg/g). Consequently, local consumption of herbal resources should be regulated to avoid abuse and long or short-term effects of drug contents as proven in the neem leaves as local herbs.
Evaluation on the Effect of Silica (DE) for Growth and Quality of Mango Kesar
Authors: Vidya A. , Hanumantharayya B. G. , Kumari R. Vasantha 
Published: January 2022

An experiment was conducted during 2012-2014 at Kittur Rani Channamma College of Horticulture, Arabhavi, Gokak (Karnataka), India to study the effect of silicon on yield and quality of mango cv. Kesar. The experiment was laid out in a randomized complete block design with nine treatments replicated five times. The results revealed that, the highest yield per tree (140.93 kg/tree) was recorded in the treatment supplemented in (T5) Half of RDF + DE 600 kg/ha which significantly more than the compared to control during 2012-2013, 2013-2014 and pooled data. It was noticed that the (T7) RDF + DE 300 kg per hectareas RDF + DE 300 kg/ha was best on the basis of physical characteristics like increased in length, diameter and volume of the fruit, and the treatment was significantly higher than the untreated control mango fruits. The treatment also helped in better chemical characteristics like increased TSS, total sugars, and reducing sugars and optimum physiological loss in weight, resulting in improved keeping quality at ambient conditions (25-350C, 50-60% RH). The T7 treatment was judged as the most effective soil application for the mango cv. Kesar that helped in increasing the quality of the mango fruits during storage even after 18 days of storage. The same treatment was also found to be more effective and significantly more than the compared to control during 2012-2013, 2013-2014 and pooled data with respect to organoleptic parameters for the mango cv. Kesar.
Awareness about Human Brucellosis in Healthcare Professional in India
Authors: Patel Jinal , Singh Suman 
Published: January 2022

Introduction: Human brucellosis is a widespread zoonosis of serious public health consequences. The infection is transmitted from animal to human through direct contact with infected animals or consumption of infected, unpasteurized animal milk. Being a disease with wide and non-specific clinical manifestations, a case of brucellosis can be detected only if the treating health care professional is aware of the disease and keeps a high rate of suspicion when dealing with suspected cases. We surveyed to find the extent of awareness about Human brucellosis in healthcare professionals in Gujarat, India.
Methodology: A cross-sectional study was conducted among healthcare professionals from December 2020 to May 2021 using a self-administrated questionnaire. This study included healthcare professionals including AYUSH practicing in Gujarat. A validated questionnaire consisting of 23 items was administered to assess the knowledge of professionals toward suspecting, diagnosing, preventing, and managing a case of brucellosis. Both physical and Google forms were used to collect data. Data were analyzed using Statistical Package for the Social Sciences (SPSS) program, IBM version 22.
Results: Sixty-nine healthcare professionals responded to the questionnaire. The findings of the study showed overall good awareness about brucellosis with a higher rate of knowledge in allopathic healthcare professionals and nurses in comparison to AYUSH doctors. Nearly 50% of respondents did not know the treatment as well as the preventive potential of human brucellosis.
Conclusion: The current study suggests a need for creating more awareness in the healthcare professional, particularly AYUSH practitioners about brucellosis for better management and prevention.
Evaluation of Anti-depressant, Anti-anxiety and Muscle Relaxant Activity of Hydroalcoholic Extract of Aerva javanica Roots
Authors: Waqas Mohammed , Sharma Peeyush Kumar , Kumar Yadav Sandeep , Asif Mohammad 
Published: January 2022

Aims: To evaluate anti-depressant, anti-anxiety and muscle relaxant activity of hydroalcoholic extract of Aerva javanica roots in various experimental animal models.
Study Design: Animal study.
Place and Duration of Study: The study was conducted in Bilwal Medchem and Research Laboratory, Jaipur from July 2021-August 2021.
Methodology: The root powder of Aerva javanica was extracted with hydroalcoholic solvent (70% ethanol). The hydroalcoholic extract at three doses 100 mg/kg, 200 mg/kg, and 400 mg/kg was checked for anti-depressant and skeletal muscle relaxant activity in the experimental animal models. To determine the anti-depressant activity tail suspension test, locomotor activity, open field test, and MAO inhibitor assay were done; to determine the anti-anxiety activity hole board test was used; and to determine the skeletal muscle relaxant activity rotarod test, grip strength test, and chimney test were done.
Results: In the tail suspension test, the extract at 200 mg/kg and 400 mg/kg significantly reduced the duration of immobility compared to normal control (p<0.0001). The extract at dose 400 mg/kg significantly reduced MAO-A and MAO-B activity compared to the normal control group (p<0.01 and p<0.05, respectively). The extract at 200 mg/kg and 400 mg/kg were able to decrease locomotor activity in actophotomoter and increased time spent in centre square in open field test revealing the sedative effect of the extract. In hole board test, the extract at dose 400 mg/kg and 200 mg/kg significantly increased number of head dip count (p<0.0001 and p<0.001) respectively. In the rotarod test, the extract at dose 200 and 400 mg/kg decreased the time spent on the rotating rod (p<0.0001), compared to normal control. Similarly, in the grip strength test the extract at dose 200 and 400 mg/kg decreased the time spend on suspended wire revealing the skeletal muscle relaxant property of the test extract.
Conclusion: Based on the result, it can be concluded that the extract exert anti-depressant, anti-anxiety and skeletal muscle relaxant like activity in the experimental rat which was hypothesized to be attributed to the flavonoids present in the hydroalcoholic root extract of Aerva javanica.
Protocol on Effect of Planned Teaching on Knowledge Regarding Menstrual Blood Banking among Nursing Students
Authors: Ngente Elizabeth Remsangzuali , Chaudhari Vaibhav , Fodekar Nita , Gathe Pranali , Ghume Samiksha , Jambhulkar Shruti , Gomase Kavita 
Published: January 2022

Background: The student’s changing habits varies depending on their intellectual level. Transition concerns are also present among college students. You have issues with your parents and siblings due to shyness and aggression. They are having academic adjustment issues as a result of the new academic pattern, atmosphere, and faculties. Academic transition includes finding inspiration, taking actions to satisfy academic obligations, and dealing with academic frustration.
Aim: To evaluate the effectiveness of planned teaching on knowledge regarding Menstrual Blood Banking among nursing students.
Methods: The data gathering process began from 5th April 2021. The investigators visited selected nursing school in Sawangi (M) Wardha City and got the mandatory authorization from the concerned authorities. To ensure better coordination during data collection, the researchers introduced themselves and told them about the purpose of the study. The researchers contacted the final year nursing students of selected area and clarified the purposes of the study and described how it will be helpful for them. They investigated their will to take part in the study and attain permission from them. They will assess their knowledge regarding Menstrual Blood Banking among Nursing Students by using structured questionnaire and after that, they will give them planned teaching regarding Menstrual Blood Banking. Then, after the seventh day of planned teaching, they will assess their post-test knowledge score regarding Menstrual Blood Banking. The investigators acknowledged all the study samples as well as the authorities for their support. The conclusion will be drawn from the results and will be published in peer reviewed journal.
Materials and Methods: The information was gathered from nursing students at nursing colleges in Wardha district. The research method was quantitative, and the study design was pre-experimental, one group pre-test post-test. The research was conducted at Wardha district's selected nursing colleges. Students make up the population, and samples were taken from 64 nursing students. The data was collected using a self-administered questionnaire and a targeted sample strategy. The tools for data collection used was -socio demographic data (age, education, religion, course, year of study and residence of the students),self-administered questionnaire on Menstrual Blood Banking and lesson plan on Menstrual Blood Banking.
Expected Results: This study is planned to assess knowledge regarding Menstrual Blood Banking among nursing students. Hence, it is expected to identify the effectiveness of planned teaching regarding Menstrual Blood Banking. The conclusion will be drawn from the results and will be published in per review journal.