bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prediction and copy number variation identification of ZNF146 gene related to growth traits in Chinese cattle
Authors: Ding X. T. , Liu X. , Li X. M. , Wen Y. F. , Xu J. W. , Liu W. J. , Li Z. M. , Zhang Z. J. , Chai Y. N. , Wang H. L. , Cheng B. W. , Liu S. H. , Hou B. , Huang Y. J. , Li J. G. , Li L. J. , Yang G. J. , Qi Z. F. , Chen F. Y. , Shi Q. T. , Wang E. Y. , Lei C. Z. , Chen H. , Ru B. R. , Huang Y. Z. 
Published: August 2022

AbstractThe great demographic pressure brings tremendous volume of beef demand. The key to solve this problem is the growth and development of Chinese cattle. In order to find molecular markers conducive to the growth and development of Chinese cattle, sequencing was used to determine the position of copy number variations (CNVs), bioinformatics analysis was used to predict the function of ZNF146 gene, real-time fluorescent quantitative polymerase chain reaction (qPCR) was used for CNV genotyping and one-way analysis of variance was used for association analysis. The results showed that there exists CNV in Chr 18: 47225201-47229600 (5.0.1 version) of ZNF146 gene through the early sequencing results in the laboratory and predicted ZNF146 gene was expressed in liver, skeletal muscle and breast cells, and was amplified or overexpressed in pancreatic cancer, which promoted the development of tumour through bioinformatics. Therefore, it is predicted that ZNF146 gene affects the proliferation of muscle cells, and then affects the growth and development of cattle. Furthermore, CNV genotyping of ZNF146 gene was three types (deletion type, normal type and duplication type) by Real-time fluorescent quantitative PCR (qPCR). The association analysis results showed that ZNF146-CNV was significantly correlated with rump length of Qinchuan cattle, hucklebone width of Jiaxian red cattle and heart girth of Yunling cattle. From the above results, ZNF146-CNV had a significant effect on growth traits, which provided an important candidate molecular marker for growth and development of Chinese cattle.
BAHA Attract to Osia conversion patients: comparison of the two systems and long-term outcomes
Authors: Szabo L , Nagy R , Posta B , Kiss J G , Rovo L , Bere Z 
Published: August 2022

AbstractObjectiveOsia is a new, transcutaneous, active bone-conduction implant. This study aimed to compare the BAHA Attract and the first-generation Osia system after BAHA Attract to Osia conversion surgery.MethodFive patients who had previously used the BAHA Attract system were converted to the first generation of the Osia system. Surgical aspects of the two different systems, audiological performance and subjective opinions of the patients were investigated. Pure tone audiometry and speech audiometry in quiet was performed with each patient's BAHA 5 sound processor on Attract, and the test battery was repeated six weeks after the Attract to Osia conversion and at different time points after the first fitting. Details of the surgery and patients' feedback were analysed.ResultsAudiology tests showed significant improvement when using either system; however, the Osia system performance was better. Based on patient feedback, all the five implantees preferred the Osia system.ConclusionThe study results suggest that the Osia system is a safe and powerful hearing implant that provides good clinical outcomes.
Finding “Harry Peglar”: Re-examining the discovery of a Franklin expedition sailor’s skeleton by the 1859 McClintock search expedition
Authors: Stenton Douglas R. 
Published: August 2022

Abstract
A review of historical documents concerning the 1859 discovery of the skeleton of a member of the 1845 Franklin expedition on southern King William Island revealed a significant but previously unrecognized geographical error about the site’s reported and mapped location. Archeological investigations conducted in 2019 established the site’s correct location and the fact that it had unwittingly been rediscovered in 1973. Misconceptions concerning the site’s location and key aspects of its interpretation highlight the importance of careful evaluation of historical and archeological data regarding the 1845 Franklin expedition.
Determination of protein–protein interactions at the single-molecule level using optical tweezers
Authors: Sánchez Wendy N. , Robeson Luka , Carrasco Valentina , Figueroa Nataniel L. , Burgos-Bravo Francesca , Wilson Christian A. M. , Casanova-Morales Nathalie 
Published: August 2022

Abstract
Biomolecular interactions are at the base of all physical processes within living organisms; the study of these interactions has led to the development of a plethora of different methods. Among these, single-molecule (in singulo) experiments have become relevant in recent years because these studies can give insight into mechanisms and interactions that are hidden for ensemble-based (in multiplo) methods. The focus of this review is on optical tweezer (OT) experiments, which can be used to apply and measure mechanical forces in molecular systems. OTs are based on optical trapping, where a laser is used to exert a force on a dielectric bead; and optically trap the bead at a controllable position in all three dimensions. Different experimental approaches have been developed to study protein–protein interactions using OTs, such as: (1) refolding and unfolding in trans interaction where one protein is tethered between the beads and the other protein is in the solution; (2) constant force in cis interaction where each protein is bound to a bead, and the tension is suddenly increased. The interaction may break after some time, giving information about the lifetime of the binding at that tension. And (3) force ramp in cis interaction where each protein is attached to a bead and a ramp force is applied until the interaction breaks. With these experiments, parameters such as kinetic constants (koff, kon), affinity values (KD), energy to the transition state ΔG≠, distance to the transition state Δx≠ can be obtained. These parameters characterize the energy landscape of the interaction. Some parameters such as distance to the transition state can only be obtained from force spectroscopy experiments such as those described here.
Design of gripping devices based on a globoid transmission for a robotic biomaterial aliquoting system
Authors: Voloshkin Artem , Rybak Larisa , Cherkasov Vladislav , Carbone Giuseppe 
Published: August 2022

AbstractEvery year the shortage of biosamples is increasing, while the requirements for their quality are constantly tightening, which requires the introduction of new technological solutions. To solve these problems, a robotic system for aliquoting biological liquid was developed. The aliquotation process is described. The station includes a serial robot on which a gripper based on a globoid worm is installed. The gripping device is parameterized and takes into account the gripping force for different finger deflections. 3D models were developed using Computer Aided Design (CAD) system tools, after which working layouts were created using 3D printing. The design process and test results are discussed to show the efficiency of the built prototype with lab tests.
EFFIGY CENSER AND FIGURINE PRODUCTION AT THE POSTCLASSIC MAYA CITY OF MAYAPAN, MEXICO
Authors: Peraza Lope Carlos , Masson Marilyn A. , Cruz Alvarado Wilberth , Russell Bradley W. 
Published: August 2022

AbstractThe spatial contexts of effigy censer and figurine molds at Mayapan, Yucatan, Mexico suggest a tightly controlled industry in which elite representatives of state government and religious orders exerted oversight over production and distribution. Attached artisans at Mayapan made these and other restricted goods for residents of palaces and patrons of the city's public buildings. The study of effigy ceramic production reveals that, like earlier, Classic period Maya kingdoms, Postclassic elites also sponsored the crafting of symbolically charged goods. This finding expands understanding of Postclassic period economic organization, which is best-known for its expansive regional market exchange. The limited distribution of effigy censers and figurines further attests their primary use in the context of state-sponsored ceremonies and, to a lesser extent, high-status mortuary settings. Unlike other places and times in Mesoamerica, neither figurines nor effigy censers are representative of household-scale religious practice for the majority of urban residents at Mayapan.
The good, the loyal or the active? MPs’ parliamentary performance and the achievement of static and progressive career ambitions in parliament
Authors: Schobess Richard , de Vet Benjamin 
Published: August 2022

AbstractAlthough often theorized, empirical research on the relationship between MPs’ parliamentary behaviour and their chances to realize career ambitions is relatively scarce. This article holistically analyses the effect of MPs’ (1) party loyalty, (2) activity level and (3) the quality of their parliamentary work on MPs’ prospects for re-election and their promotion to higher parliamentary office. Based on a unique combination of behavioural and peer assessment data on 325 federal and regional MPs in Belgium (2014–2019), we find that particularly MPs’ loyalty and activity level improve their career prospects in the subsequent term, in contrast to more qualitative aspects of their parliamentary work. These findings provide important new insights into how and to what degree legislators are rewarded for their parliamentary performance.
A novel compact quad-band planar antenna using meander-line, multi-stubs, and slots for WiMAX, WLAN, LTE/5G sub-6 GHz applications
Authors: Maamria Tarek , Challal Mouloud , Benmahmoud Fateh , Fertas Khelil , Mesloub Ammar 
Published: August 2022

AbstractThis article concerns the design of a new quad-band monopole antenna with a specific configuration and reduced size. The antenna design is based on a single step meander-line parasitic structure, parasitic stubs, and double inverted L-shaped defected microstrip structure units on the top side of the substrate, and double rectangular-shaped defected ground structure units along with partial ground plane on the bottom side. This design procedure allows to achieve quad-band characteristics and improve the impedance matching. The fabricated antenna prototype with overall dimensions of (0.24λ0 × 0.17λ0 × 0.013λ0) is operating at 2.55, 3.65, 4.65, and 5.8 GHz with fractional bandwidth about 7.7, 12.84, 9.23, and 12.8%, respectively. The antenna exhibits an omnidirectional and a monopole like radiation patterns in the H- and E-planes, respectively, with suitable gains between 2.1 and 3.75 dBi. The measurement results are in good agreement with simulation values, which indicates that the proposed antenna design is suitable for WiMAX, LTE B7 (2.52–2.75 GHz), Sub-6 GHz 5G (n77) (3.39 – 3.87 GHz), Sub-6 GHz 5G (n78) (4.4–4.86 GHz), and WLAN, LTE B46 (5.1–5.82 GHz) wireless applications.
Dietary Transition Determining the Tradeoff Between Global Food Security and Sustainable Development Goals Varied in Regions
Authors: Liu Yujie , Tan Qinghua , Chen Jie , Pan Tao , Penuelas Josep , Zhang Jie , Ge Quansheng 
Published: August 2022

AbstractGlobal food security is directly linked to human health and sustainable development. It is critical to comprehensively twig future changes in global food demand and progress in implementing the United Nations Sustainable Development Goals (SDGs), considering the transition of dietary patterns. We presented a global‐scale analysis quantifying the status of national food consumption and SDG performance in 2017, and the food demands and SDG index scores in 2030 were predicted under three healthy dietary patterns using 11 SDG indicators. High‐income nations scored well on most SDG indicators but poorly on food waste and the environment. Total global food demand was projected to be the highest under the national dietary guidelines pattern (12.69–13.37 million ton/d) and the lowest under the WHO healthy diet pattern (10.55–11.18 million ton/d). However, food demand under different dietary patterns varied among regions. Transitioning from current diets to healthy diets was projected to gain SDG index score for most countries. Strategies for shifts in dietary patterns to determine the tradeoff between global food security and sustainable development should be tailored to local conditions. The EAT‐Lancet dietary pattern is an optimal choice for determining the tradeoff between food security and sustainable development on a global scale. Given the current status of food access and nutrition, the National and the WHO dietary patterns are recommended for Asia and Africa, respectively.
Kinetic Generation of Whistler Waves in the Turbulent Magnetosheath
Authors: Svenningsson I. , Yordanova E. , Cozzani G. , Khotyaintsev Yu. V. , André M. 
Published: August 2022

AbstractThe Earth's magnetosheath (MSH) is governed by numerous physical processes which shape the particle velocity distributions and contribute to the heating of the plasma. Among them are whistler waves which can interact with electrons. We investigate whistler waves detected in the quasi‐parallel MSH by NASA's Magnetospheric Multiscale mission. We find that the whistler waves occur even in regions that are predicted stable to wave growth by electron temperature anisotropy. Whistlers are observed in ion‐scale magnetic minima and are associated with electrons having butterfly‐shaped pitch‐angle distributions. We investigate in detail one example and, with the support of modeling by the linear numerical dispersion solver Waves in Homogeneous, Anisotropic, Multicomponent Plasmas, we demonstrate that the butterfly distribution is unstable to the observed whistler waves. We conclude that the observed waves are generated locally. The result emphasizes the importance of considering complete 3D particle distribution functions, and not only the temperature anisotropy, when studying plasma wave instabilities.
Extreme Poleward Expanding Super Plasma Bubbles Over Asia‐Pacific Region Triggered by Tonga Volcano Eruption During the Recovery‐Phase of Geomagnetic Storm
Authors: Rajesh P. K. , Lin C. C. H. , Lin J. T. , Lin C. Y. , Liu J. Y. , Matsuo T. , Huang C. Y. , Chou M. Y. , Yue J. , Nishioka M. , Jin H. , Choi J. M. , Chen S. P. , Chou Marty , Tsai H. F. 
Published: August 2022

AbstractThe Tonga volcano eruption of 15 January 2022 unleashed a variety of atmospheric perturbations, coinciding with the recovery‐phase of a geomagnetic storm. The ensuing thermospheric variations created rare display of extreme poleward‐expanding conjugate plasma bubbles seen in the rate of total electron content index over 100–150°E, reaching ∼40°N geographic latitude. This is associated with fluctuations in FORMOSAT‐7/COSMIC‐2 (F7/C2) ion‐density measurements and spread‐F in ionograms. Preceding to this, an unusually strong pre‐reversal enhancement (PRE) occurred in the global ionospheric specification (GIS) electron density profiles derived from F7/C2 observations. The GIS also revealed a decrease of equatorial ionization anomaly (EIA) crest density due to the storm impact. Reduced E‐region conductivity by volcano‐induced waves and enhanced F‐region wind, further accelerated by reduced ion‐drag over the EIA, apparently intensified the PRE. Accompanied with the strong PRE, volcano‐induced seed perturbations triggered the super plasma bubble activity.
Changes of Tropical Cyclones Landfalling in China From 1979 to 2018
Authors: Li Guangxin , Li Qinglan , Xu Yinglong , Xu Pengcheng , Wang Wenlan , Huang Dian , Wu Yueyuan , He Lunkai 
Published: August 2022

AbstractThis study investigates the long‐term changes of tropical cyclones (TCs) that originated over the western North Pacific (WNP) and made landfall in China from 1979 to 2018. The TC best track data sets from the three primary weather agencies, the China Meteorological Administration (CMA), the Japan Meteorological Agency (JMA), and the Joint Typhoon Warning Center (JTWC), and the TCs landfall data from the CMA are used in this study. Trend analysis of the mean locations of the TCs' lifetime maximum intensity (LMI) suggests that the locations of the LMI of TCs have moved closer to the coast gradually. This shift may be associated with a landward migration of TC genesis. The changes in TC LMI possibly contribute to the slight increase in the TCs' landfall intensity and the significant growth of TCs' overland duration. Further analyses indicate that all these changes may be mainly due to both dynamic and thermodynamic conditions in the WNP, which tend to be more favorable for the formation and development of TCs, and some of the favorable conditions have shifted toward the land during the 40 years.
Convective Updraft and Downdraft Characteristics of Continental Mesoscale Convective Systems in the Model Gray Zone
Authors: Wang Dié , Prein Andreas F. , Giangrande Scott E. , Ramos‐Valle Alexandra , Ge Ming , Jensen Michael P. 
Published: August 2022

AbstractThe “gray zone” of convective modeling is defined as the range of horizontal grid spacings (Δx) at which turbulent transport processes are only partially resolved by the dynamics of the numerical model. This zone typically covers Δx from a few kilometers to several hundred meters, wherein the realistic representation of convective cloud processes can be challenging. This study characterizes the convective draft behaviors at multiple Δx across the gray zone and determines the appropriate Δx that can reliably capture these salient convective properties. We perform an ensemble of idealized simulations of mesoscale convective systems (MCS) using the Weather Research and Forecasting model at various Δx from 4 km to 250 m over the central U.S. An evaluation of key MCS kinematic properties is constrained using unique, long‐term vertical velocity estimates obtained by radar wind profilers deployed by the Department of Energy Atmospheric Radiation Measurement user facility. MCS simulations for all Δx tested overestimate (underestimate) the probabilities of convective updrafts (downdrafts) compared to the observations. In terms of the convective draft intensity, finer‐Δx models overestimate the updraft intensity, while the opposite is found for downdrafts. Moving from Δx = 4 km to 250 m, downdrafts become stronger and more frequent especially at middle and upper levels, attributed to additional drag from an increasing graupel frequency and compensation of enhanced updraft velocity. Simulated draft characteristics, including core size, intensity, and probability of occurrence, exhibit pronounced changes at Δx greater than 500 m, but suggest less sensitivity when Δx is reduced below 500 m.
Specifying Satellite Drag Through Coupled Thermosphere‐Ionosphere Data Assimilation of Radio Occultation Electron Density Profiles
Authors: Dietrich Nicholas , Matsuo Tomoko , Hsu Chih‐Ting 
Published: August 2022

AbstractThe largest obstacle to managing satellites in low Earth orbit (LEO) is accurately forecasting the neutral mass densities that appreciably impact atmospheric drag. Empirical thermospheric models are often used to estimate neutral densities but they struggle to forecast neutral densities during geomagnetic storms when they are highly variable. Physics‐based models are thus increasingly turned to for their ability to describe the dynamical evolution of neutral densities. However, these models require observations to constrain dynamical state variables to be able to forecast mass densities with adequate fidelity. The LEO environment has scarce neutral state observations. Here, we demonstrate, in simulated experiments, a reduction in orbit errors and neutral densities using a physics‐based, data assimilation approach with ionospheric observations. Using a coupled thermosphere‐ionosphere model, the Thermosphere Ionosphere Electrodynamics General Circulation Model, we assimilate Constellation Observing System for Meterology, Ionosphere, and Climate electron density profiles (EDPs) derived from radio occultation (RO) observations. We use the EDPs to directly update neutral states, improving errors for neutral temperature by 70% and neutral winds by 20%. Updated neutral temperature and neutral winds additionally improve helium composition errors by 60% and 40%, respectively. Improved neutral density estimates correspond to a reduction in orbit errors of 1.2 km over 2 days, a 70% reduction over a no‐assimilation control, and a 29 km improvement over 9 days. This study builds on the results of our earlier work to further develop and demonstrate the potential of using a vast and growing RO data source, with a physics‐based model, to overcome our limited number of neutral observations.
Content and delivery preferences for information to support the management of high blood pressure
Authors: Chapman N. , Marques F. Z. , Picone D. S. , Adji A. , Broughton B. R. S. , Dinh Q. N. , Gabb G. , Lambert G. W. , Mihailidou A. S. , Nelson M. R. , Stowasser M. , Schlaich M. , Schultz M. G. , Mynard J. P. , Climie R. E. 
Published: August 2022

AbstractBlood pressure(BP) management interventions have been shown to be more effective when accompanied by appropriate patient education. As high BP remains poorly controlled, there may be gaps in patient knowledge and education. Therefore, this study aimed to identify specific content and delivery preferences for information to support BP management among Australian adults from the general public. Given that BP management is predominantly undertaken by general practitioners(GPs), information preferences to support BP management were also ascertained from a small sample of Australian GPs. An online survey of adults was conducted to identify areas of concern for BP management to inform content preferences and preferred format for information delivery. A separate online survey was also delivered to GPs to determine preferred information sources to support BP management. Participants were recruited via social media. General public participants (n = 465) were mostly female (68%), >60 years (57%) and 49% were taking BP-lowering medications. The management of BP without medications, and role of lifestyle in BP management were of concern among 30% and 26% of adults respectively. Most adults (73%) preferred to access BP management information from their GP. 57% of GPs (total n = 23) preferred information for supporting BP management to be delivered via one-page summaries. This study identified that Australian adults would prefer more information about the management of BP without medications and via lifestyle delivered by their GP. This could be achieved by providing GPs with one-page summaries on relevant topics to support patient education and ultimately improve BP management.