bluuebunny/crossref_metadata_2025_split huggingface dataset:
SEKEDAR MELENGKAPI ATAU MEMENUHI SYARAT DEMOKRASI? MEMBACA TINGKAT PARTISIPASI PEREMPUAN DALAM PEMILU 2019 DI KOTA BEKASI
Authors: Marzoeki Choirunnisa 
Published: September 2022

This article discusses about the level of women's participation in the 2019 general elections in Bekasi City. The participation of women in general elections can be seen from the participation of women as voters, an election organizers, and election participants. Based on the final voter list, there are 50.24% women voters in Bekasi, which is more than men voters. However, this large number is not correlated with women representation in legislative institutions or election organizers.The affirmative action that was fought for since the 2004 election regarding the quota of 30% for women in the parliament until the 2019 election has never been reached. The number of women's votes acquired in the 2019 elections in Bekasi City was 16% or 8 elected candidates of 50 total elected candidates. The legislative candidates with the top serial number still occupy votes. On the other hand, women candidates who have first serial number are only 24%. The representation of women in the election management as regulated in the Law on Election Organizer uses the word "pay attention to" for at least 30% (thirty percent) of women representation. The word "pay attention" implies the sense that there is no obligation or necessity for the composition of women as much as 30 percent both in the General Election Commission and in the Election Supervisory Agency. So that the number of women in election organizer is still very low, starting from the national level to the lowest level.
STUDI KORELASI ANTARA ADVERSITY INTELLIGENCE DENGAN KOMPETENSI PROFESIONAL GURU GEOGRAFI SE- KECAMATAN BEKASI TIMUR KOTA BEKASI
Authors: Maulana Yoga Candra , - Adrian 
Published: September 2022

Penelitian ini bertujuan untuk mengetahui hubungan antara adversity intelligence dengan tingkat kompetensi profesionalnya pada guru-guru geografi se Kecamatan Bekasi Timur Kota Bekasi. Pendekatan penelitian yang digunakan adalah pendekatan kuantitatif dengan metode penelitiannya survey studi asosiatif/ studi korelasi. Populasi penelitiannya adalah seluruh guru geografi yang ada di Kecamatan Bekasi timur yang berjumlah 21 orang. Kesimpulan penelitian ini adalah sebagai berikut (1) tingkat adversity intelligence pada guru-guru geografi se Kecamatan Bekasi Timur Kota Bekasi dikategorikan tinggi dan merata. (2) tingkat komptensi profesional guru-guru geografi se Kecamatan Bekasi Timur Kota Bekasi beragam dan dominan 23,81 % pada kategori sedang, 52,38 % berada pada kategori tinggi. (3) terdapat hubungan signifikan antara adversity intelligence dengan tingkat kompetensi profesionalnya pada guru-guru geografi se Kecamatan Bekasi Timur Kota Bekasi. sebesar 2,86 dan t tabel sebesar 1,681 menunjukkan bahwa thitung lebih besar dari ttabel (t hitung > t tabel), maka hasil hipotesis penelitian H1 diterima dan H0 ditolak yang berarti terdapat hubungan antara variabel X dan variabel Y pada penelitian ini. Rekomendasi adalah sebagai berikut (1) guru melakukan peningkatan kompetensi profesional pada bidang penelitian dan pengembangan diri melalui workshop dan pelatihan-pelatihan. (2) pembinaan oleh pihak internal sekolah yang berkesinambungan dalam meningkatkan profesionalisme guru. (3) optimalisasi MGMP dalam pembinaan dan pengembangan kompetensi profesional, dan mengasah kecerdasan adversity guru geografi dalam mengadaptasi perubahan dan tantangan dalam dunia pendidikan
RANCANG BANGUN MEDIA PEMBELAJARAN LAS LISTRIK DI BENGKEL POLITEKNIK DHARMA PATRIA KEBUMEN
Authors: Setyawan Tri Dedi , Lail Nur Nidzam , Nasrullah Hamid 
Published: September 2022

Pengujian pada rancang bangun media las listrik bertujuan untuk menguji media pembelajaran pada praktikum mata kuliah teknologi pembentukan dasar dengan bilik penutup menggunakan bahan logam seng sebagai pembatas ruangan dengan tempat praktikum lainnya, rancang bangun media las listrik merupakan media yang di gunakan pada praktikum mata kuliah teknologi pembentukan dasar. Metode penelitian yang kami digunakan adalah menggunakan metode penelitan deskriptif dan dokumentasi. Hasil peelitian yang kami ujikan bertujuan untuk menguatkan hasil yang kami teliti agar memiliki kaitan yang erat dengan inti dari permasalahan maka pengambilan data dengan cara observasi dan studi kepustakaan. Hasil penguji pada rancang bangun media las listrik yaitu: 1) Daya kerja pada transformator dapat bekerja maksimal dengan amper rendah maupun amper tinggi, 2) blower exhause fanmerk KDX dengan kecepatan 910 RPM mampu menyerap asap hasil pengelasan 87% dengan suhu ruangan suhu 40˚C, dan 3) penilain dari hasil quisioner siswa praktikum mendapat perbandingan sangat efektif 57%, efektif 4%, kurang efektif 1%.
PENGARUH VARIASI PERSENTASE REDUKSI PADA PROSES WIRE DRAWING TERHADAP KEKERASAN DAN KEKUATAN TARIK KAWAT S45C
Authors: Prahastowo Yogan Daru , Oktadinata Herry 
Published: September 2022

Persentase reduksi yang terjadi pada proses wire drawing mengakibatkan perubahan sifat mekanik. Pada Proses wire drawing ini terjadinya suatu fenomena pengerasan regangan, selain meningkatkan kekuatan Tarik dan kekerasan bahan, juga meningkatkan kegetasan bahan. Berkaitan dengan hal tersebut maka dilakukan penelitian pengaruh variasi presentase reduksi pada proses wire drawing terhadap kekuatan tarik dan kekerasan kawat S45C. Tujuan penelitian ialah untuk memperoleh data dan hasil kekuatan tarik dan kekerasan kawat, dan mengetahui akibat dan pengaruh variasi reduksi terhadap kekuatan tarik kawat, kekerasan kawat, dan perubahan sturuktur mikro kawat yang terjadi setelah proses wire drawing dengan variasi persentase reduksi. hasil penelitian meliputi foto mikrostruktur, nilai kekerasan material dan kekuatan tarik kawat. Dalam penelitian ini spesimen uji adalah kawat S45C.
Penelitian ini dilakukan variasi persentase reduksi sebesar 36% dan 25% kemudian direduksi kembali sebesar 10%. Didapat hasil eksperimen adalah nilai kekerasan paling tinggi pada kawat hasil reduksi 25% dan direduksi kembali 10% yaitu dengan nilai 183,71 HV, hasil drawing dengan reduksi 36% memiliki pertambahan nilai kekuatan tarik paling tinggi sebesar 118,07 MPa. Adapun nilai kekuatan tarik paling tinggi adalah 558,84 MPa yaitu pada kawat hasil reduksi 25% dan direduksi kembali 10%. Dalam foto struktur mikro ditemukan terjadinya perubahan dengan terlihatnya garis-garis memanjang yang menandakan terjadi nya dislokasi. Dislokasi terbesar terlihat pada kawat yang direduksi 36%.
Terminal group effects of DOPO-conjugated flame retardant on polyamide 6: Thermal stability, flame retardancy and mechanical performances
Authors: Gao Jing , He Wentao , Xiang Yushu , Long Lijuan , Qin Shuhao 
Published: September 2022

Two DOPO-conjugated flame retardants with or without amino terminal groups (DOPO-NH2 and DIDOPO, respectively) were synthesized and incorporated into polyamide 6 (PA6). Results demonstrated the DOPO-NH2 endowed superior thermal, flame retardant and mechanical performances to PA6 composites. With the same loading of 15 wt%, DOPO-NH2 can catalyze the PA6 matrix more effectively and result in more residues at high temperature. The PA6 composites containing DOPO-NH2 exhibited higher LOI (28.0%) compared to 25.0% for the sample containing DIDOPO, and the lower heat release capacity and peak heat release rate. Furthermore, the overall mechanical properties of PA6 composites containing DOPO-NH2 outperformed the samples containing DIDOPO, even superior to that for PA6. Such a significant difference can be mainly attributed to the existence of amino-terminal group, which can interact with carboxyl group in PA6 as confirmed by dynamic mechanical analysis, improving the compatibility between the flame retardant and PA6 matrix.
Non-invasive assessment of acute heart failure by Stevenson classification: Does echocardiographic examination recognize different phenotypes?
Authors: Palazzuoli Alberto , Ruocco Gaetano , Valente Serafina , Stefanini Andrea , Carluccio Erberto , Ambrosio Giuseppe 
Published: September 2022

BackgroundAcute heart failure (AHF) presentation is universally classified in relation to the presence or absence of congestion and the peripheral perfusion condition according to the Stevenson diagram. We sought to evaluate a relationship existing between clinical assessment and echocardiographic evaluation in patients with AHF.Materials and methodsThis is a retrospective blinded multicenter analysis assessing both clinical and echocardiographic analyses during the early hospital admission for AHF. Patients were categorized into four groups according to the Stevenson presentation: group A (warm and dry), group B (cold and dry), group C (warm and wet), and group D (cold and wet). Echocardiographic evaluation was executed within 12 h from the first clinical evaluation. The following parameters were measured: left ventricular (LV) volumes, LV ejection fraction (LVEF); pattern Doppler by E/e1 ratio, pulmonary artery systolic pressure (PASP), tricuspid annular plane systolic excursion (TAPSE), and inferior cave vein diameter (ICV).ResultsWe studied 208 patients, 10 in group A, 16 in group B, 153 in group C, and 29 in group D. Median age of our sample was 81 [69–86] years and the patients enrolled were mainly men (66.8%). Patients in groups C and A showed significant higher levels of systolic arterial pressures with respect to groups B and D (respectively, 130 [115–145] mmHg vs. 122 [119–130] mmHg vs. 92 [90–100] mmHg vs. 95 [90–100] mmHg, p &lt; 0.001). Patients in groups A and C (warm) demonstrated significant higher values of LVEF with respect to patients in groups B and D (43 [34–49] vs. 42 [30–49] vs. 27 [15–31] vs. 30 [22–42]%, p &lt; 0.001). Whereas group B experienced significant lower TAPSE values compared with other group (14 [12–17] mm vs. A: 17 [16–21] mm vs. C: 18 [14–20] mm vs. D: 16 [12–17] mm; p = 0.02). Finally, echocardiographic congestion score including PASP ≥ 40 mmHg, ICV ≥ 21, mm and E/e’ &gt; 14 did not differ among groups. Follow-up analysis showed an increased mortality rate in D group (HR 8.2 p &lt; 0.04).ConclusionThe early Stevenson classification remains a simple and universally recognized approach for the detection of congestion and perfusion status. The combined clinical and echocardiographic assessment may be useful to better define the patients’ profile.
Left atrial anatomical variations correlate with atrial fibrillation sources near the left atrial ridge
Authors: Gagyi Rita B. , Szegedi Nándor , Simon Judit , Wijchers Sip , Bhagwandien Rohit , Kong Melissa H. , Ruppersberg Peter , Szili-Torok Tamas 
Published: September 2022

IntroductionAnatomical variations and characteristics of the left atrium (LA) may have a previously undescribed effect on source locations in atrial fibrillation (AF). This is the first study aiming to investigate the relationship between anatomical characteristics of the LA and non-PV sources detected by electrographic flow (EGF) mapping in patients with persistent AF.Materials and methodsWe analyzed cardiac computed tomography (CT) and EGF mapping data in patients who underwent radiofrequency catheter ablation (CA). EGF mapping is a novel method based on Horn–Schunk flow estimation algorithm, used to estimate cardiac action potential flow in the atria that can detect AF sources in patients with persistent AF. By analyzing EGF maps obtained during CA procedures, we localized non-PV sources in the LA.ResultsThirty patients were included in this study (mean age 62.4 ± 6.8 years). Ten patients had AF sources near the LA ridge, while twenty patients had no leading source (source activity &gt; 26%) near the LA ridge. LA anatomical characteristics, left atrial appendage (LAA) length, and ostial diameter showed no correlation with the presence of a leading source. We documented 19 patients with abutting LAA and left superior pulmonary vein (LSPV) (distance &lt; 2 mm), and 11 patients with non-abutting LAA–LSPV (distance &gt; 2 mm). Three out of 19 patients presented with a leading source near ridge in the abutting LAA–LSPV group, while 7 out of 11 patients presented with a leading source near the ridge in the non-abutting LAA-LSPV group (p = 0.01).ConclusionOur data suggests that non-abutting LAA-LSPV is associated with the presence of AF sources near the LA ridge.
Clinical characteristics and risk factors of in-hospital gastrointestinal bleeding in patients with acute myocardial infarction
Authors: Zhong Liang , Quan Xingpu , Dang Peizhu , Tang Manyun , Yu Hang , Guo Fengwei 
Published: September 2022

BackgroundGastrointestinal bleeding (GIB) is one of the most serious complications of acute myocardial infarction (AMI) and is correlated with poor outcomes.ObjectiveTo evaluate the prevalence, risk factors and in-hospital mortality of GIB in patients with AMI.MethodsThis observational case-control study retrospectively enrolled consecutive patients with AMI from the Department of Cardiovascular Medicine and Cardiovascular Surgery of the First Affiliated Hospital of Xi'an Jiaotong University from January 2015 to December 2020. GIB after AMI was identified by International Classification of Diseases (ICD) codes from inpatient medical settings and validated by medical record review. AMI patients without GIB were accordingly classified as the control group. Propensity score matching (PSM) was used to match with the GIB group and the control group. All anonymized clinical data were provided by the Biobank of the First Affiliated Hospital of Xi'an Jiaotong University.ResultsA total of 5,868 AMI patients were enrolled, 0.87% (51/5,868) of whom developed GIB after AMI. On the univariate analysis, history of diabetes, chronic kidney disease, Killip IV, a lower hemoglobin concentration, a higher serum level of creatinine, blood urea nitrogen and D-dimer were closely associated with the risk of GIB (P &lt; 0.05). On the multivariable analysis, a lower hemoglobin concentration (OR: 0.93, 95% CI: 0.89–0.96, P &lt; 0.001) was independently associated with the risk of GIB. Patients with GIB had a much higher in-hospital mortality rate than those without GIB (14.3 vs. 2.1%, P = 0.047). In-hospital mortality among patients with GIB after AMI appeared to be associated with a decreased hemoglobin concentration (OR: 0.93, 95% CI: 0.86–0.99, P = 0.045) and Killip IV (OR: 51.59, 95% CI: 2.65–1,005.30, P = 0.009).ConclusionThe history of diabetes, poor renal function and heart failure were associated with the high risk of GIB in patients experiencing AMI. The in-hospital mortality in patients with AMI complicating GIB was higher than that in patients without GIB and was associated with a decreased hemoglobin concentration and high Killip classification.
A novel method for measuring pulmonary artery pressure by high-frequency ultrasound-guided transthoracic puncture in rats
Authors: Zhang Xiaofeng , Li Jingtao , Zeng Decai , Liang Chunting , Zhong Yanfen , Huang Tongtong , Mo Yingying , Rao Huaqing , Pan Xiaoxiong , Wu Ji 
Published: September 2022

ObjectivesThe success of the rat model of pulmonary hypertension (PH) is primarily dependent on the measurement of pulmonary artery pressure. We herein demonstrate a novel method for measuring pulmonary artery pressure through a high-frequency ultrasound-guided transthoracic puncture in rats. The efficacy and time of this novel method are also discussed.MethodsA single subcutaneous injection of monocrotaline (MCT) was used to establish a rat model of PH. Through the heat shaping method, the tip of that puncture cannula was maintained at a certain angle after the needle core was removed. In-plane real-time guided trocar puncture of the right ventricular outflow tract was performed in the short-axis section of the parasternal aorta. The external pressure sensor was used to record the real-time waveform of right ventricular systolic pressure, pulmonary artery systolic pressure, and diastolic pressure.ResultsThe success rates of which using this novel method in the model group and the control group were 88.5 and 86.7%, respectively. The time of puncture pressure measurement was 164 ± 31 and 235 ± 50 s, respectively. The right ventricular systolic blood pressure, pulmonary systolic blood pressure, and diastolic blood pressure of the model group were higher than those of the control group.ConclusionThe modified method for trocar is helpful for accurately positioning pulmonary artery manometry. The method described in this paper has a high success rate and short operation time. It can simultaneously measure systolic blood pressure, diastolic blood pressure, and mean pressure of the right ventricle and pulmonary artery. It has a broad application prospect in verifying the rat PH model and pulmonary artery pressure monitoring.
Case report: A homozygous ADAMTSL2 missense variant causes geleophysic dysplasia with high similarity to Weill-Marchesani syndrome
Authors: Li Mojiang , Li Yingshu , Liu Huixing , Zhou Haiyan , Xie Wanqin , Peng Qinghua 
Published: September 2022

Background: Geleophysic dysplasia and Weill-Marchesani syndrome from the acromelic dysplasias group of genetic skeletal disorders share remarkable clinical and genetic overlap.Methods: Ophthalmological, physical, radiological examinations were conducted with a female patient in her early 30 s. Whole exome sequencing followed by Sanger sequencing validation was performed to identify the genetic cause.Results: The patient, born to consanguineous Chinese parents, presented with microspherophakia, lens subluxation, high myopia, short statue, small hands and feet, stiff joints, and thickened skin. A diagnosis of Weill-Marchesani syndrome was initially made for her. However, genetic testing reveals that the patient is homozygous for the c.1966G&gt;A (p.Gly656Ser) variant in ADAMTSL2, and that the patient’s healthy mother and daughter are heterozygous for the variant. As mutations in ADAMTSL2 are known to cause autosomal recessive geleophysic dysplasia, the patient is re-diagnosed with geleophysic dysplasia in terms of her genotype and phenotype.Conclusion: The present study describes the clinical phenotype of the homozygous ADAMTSL2 p. Gly656Ser variant, which increases our understanding of the genotype-phenotype correlation in acromelic dysplasias.
Low ankle-brachial index and cognitive function after stroke—the PROSpective with Incident Stroke Berlin (PROSCIS-B)
Authors: Stillfried Maria R. V. , Sperber Pia S. , Broersen Leonie H. A. , Huo Shufan , Piper Sophie K. , Heuschmann Peter U. , Endres Matthias , Siegerink Bob , Liman Thomas G. 
Published: September 2022

IntroductionLow ankle-brachial index (ABI) ≤0. 9 is a marker for generalized atherosclerosis and a risk factor for cognitive decline in the general population.ObjectiveTo evaluate the impact of ABI ≤0.9 on cognitive function up to 3 years after first-ever ischemic stroke.MethodsData was used from the “PROspective Cohort with Incident Stroke-Berlin” (PROSCIS-B; NCT01363856). ABI was measured at baseline and categorized into normal (1.4–0.9) vs. low (≤0.9). Cognitive function was assessed with the Montreal Cognitive Assessment (MoCA) and the Mini-Mental-State-Examination (MMSE) at baseline and with the Telephone Interview for Cognitive Status-modified (TICS-m) at 1–3 years of follow-up. We performed confounder adjusted generalized linear models (GLM) to calculate relative risks (RR) for cognitive impairment at baseline (MMSE≤26; MoCA≤25) and linear mixed models (LMM) to estimate the impact of low ABI on TICS-m over time.ResultsWe included 325 patients [mean age: 66 (SD = 13); 38% female, median NIHSS = 2 (IQR = 1–4), ABI≤0.9: 59 (18%)]. Patients with low ABI were at increased risk of cognitive impairment at baseline (adjusted RR for MoCA≤25 = 1.98; 95%-CI:1.24 to 3.16). TICS-m scores were consistently lower over time in patients with low ABI (adjusted ß = −1.96; 95%-CI:−3.55 to −0.37). Independent of ABI, cognitive function did not decline over time (adjusted ß:0.29; 95%-CI:−0.06 to 0.64).ConclusionIn patients with mild to moderate first-ever ischemic stroke, low ABI is associated with reduced cognitive function over a 3-year follow-up.Study Registrationhttps://clinicaltrials.gov; Unique identifier: NCT01363856.
Bioactive peptides identification and nutritional status ameliorating properties on malnourished rats of combined eel and soy-based tempe flour
Authors: Sabrina Nindy , Rizal Mochammad , Nurkolis Fahrul , Hardinsyah Hardinsyah , Tanner Melvin Junior , Gunawan William Ben , Handoko Matthew Nathaniel , Mayulu Nelly , Taslim Nurpudji Astuti , Puspaningtyas Dwi Sari , Noor Sutamara Lasurdi , Yusuf Vincentius Mario , Permatasari Happy Kurnia , Radu Son 
Published: September 2022

Background and aimsA combined eel and soy-based tempe (CEST) flour is rich in nutrients, especially its high amino acid content in which bioactive peptides (BPs) are expected to be found. Hence, this research aimed to identify the BPs of CEST flour and CEST supplementation’s effect on improving nutritional status biomarkers by ameliorating serum protein, hemoglobin, and IGF-1 of malnourished rats.MethodsCEST flour with a ratio of eel and soy-based tempe of 1:3.5 was produced by applying the oven drying method. Amino acid sequences from six BPs were analyzed using a protein sequencer and spectrometer-electrospray ionization (MS-ESI). A total of thirty malnourished male Rattus norvegicus aged 3–4 weeks were given low-protein (LP; 4% w/w protein) diet treatment for 4 weeks. Afterward, rats were divided into 3 groups of 10 rats. Group A and B remained on a low-protein diet for 4 weeks, receiving an LP diet and getting doses of CEST of 100 and 200 mg/kg BW, respectively, via oral. Group C or control was given a Normal-protein (NP) diet (23% w/w of protein) and was allowed to feed ad libitum during the trial period without a dose of CEST.ResultsSix bioactive peptides were found, with WMGPY being the most abundant, along with a DPPH radical scavenging activity of 5.0 mg/mL. The results showed that serum protein, hemoglobin, and IGF-1 of group B were significantly higher compared to groups A and C (p = 0.0021). CEST dose of 200 mg/kg BW was more effective to increase serum levels of protein (p = 0.0052), hemoglobin, and IGF-1 (p &lt; 0.0001) compared to a 100 mg/kg BW dose.ConclusionThis indicates that the CEST flour has six bioactive peptides, which may contribute to the improvement of nutritional status biomarkers. To establish its potential impact, a human clinical study is urgently needed.
Case report: Alpelisib-induced Stevens–Johnson syndrome
Authors: Kurian Christine Jane , Desai Akshay , Rafferty William , Abou Hussein Ahmed Kamel 
Published: September 2022

BackgroundAlpelisib is a recently approved treatment for hormone receptor-positive, HER2-negative, PIK3CA-mutated advanced breast cancer. It has been associated with alopecia and rash, but there are no documented cases of Stevens–Johnson Syndrome (SJS) associated with this drug. Here, we detail the first case of SJS associated with alpelisib.Case descriptionOur patient is a 60-year-old woman with a past medical history of metastatic hormone receptor-positive (ER+ 80% and PR+ 1%), HER2-negative metastatic breast cancer who presented with acute odynophagia, fevers, and diffuse body rash after receiving her first doses of alpelisib and fulvestrant in the preceding days. She presented to the emergency department after developing a whole-body rash and severe ulceration of her buccal mucosa. She was started on methylprednisolone with remarkable improvement in symptoms.ConclusionThis case report details the only report of SJS following alpelisib treatment. Immediate cessation of drugs and initiation of steroids are the cornerstone of treatment. Patients who experience such side effects will have to be monitored closely for long-term sequelae associated with SJS, including cutaneous, ocular, and oral sequelae, all of which can profoundly affect the quality of life for cancer patients.