bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pelatihan Pembuatan Bahan Handsanitizer Alami dengan Esktrak Aloe vera Sebagai Upaya Pencegahan Covid-19 di Desa Pulorejo
Authors: Fitria Ana , Zulfikar Zulfikar , Risvi M , Arifah Yenny Lidya , Muhibuddin Anton 
Published: May 2022

ABSTRACT
According to the community's need for limited hand sanitizer, training is needed to make natural hand sanitizer. The materials needed are easy to obtain which can support the success of making a hand sanitizer without compromising some of the important components of a hand sanitizer. The socialization delivered at community service activities in Pulorejo village was the use and use of natural hand sanitizer products with aloe vera extract. This product introduction aims to create a community personality who has expertise and knowledge that can take advantage of the surrounding natural resources, so that independence can be created in society by introducing high-value productivity efforts. The results of the training show that there is an increase in public understanding of the manufacture of natural hand sanitizers by 17.56% so this activity is quite effective for the community to overcome the current Covid condition.

Keywords: Natural Hand Sanitizer, Aloe vera Extract, Training

ABSTRAK
Sesuai kebutuhan masyarakat terhadap terbatasnya hand sanitizer maka perlu pelatihan membuat handsanitizer alami. Bahan yang dibutuhkan mudah diperoleh yang bisa menunjang keberhasilan pembuatan handsinitizer tanpa mengurangi beberapa komponen-komponen penting handsanitizer. Sosialisasi yang disampaikan pada kegiatan pengabdian kepada masyarakat di desa Pulorejo adalah pemanfaatan dan kegunaan produk handsanitizer alami dengan ekstrak lidah buaya. Pengenalan produk ini bertujuan untuk menciptakan kepribadian masyarakat yang memiliki keahlian dan ilmu yang bisa memanfaatkan sumber daya alam sekitar, sehingga kemandirian bisa diciptakan dalam suatu masyarakat dengan upaya pengenalan produktifitas yang mempunyai nilai tinggi. Hasil pelatihan menunjukkan bahwa ada peningktaan pemahaman masyarakat terhadap pembuatan handsanitizer alami sebesar 17,56% sehingga kegiatan ini cukup efektif bagi masyarakat untuk mengatasi kondisi Covid sekarang ini.
Diversidad de ideas construidas por estudiantes sobre los números reales, los números irracionales, el orden y la densidad
Authors: Montoro Virginia 
Published: May 2022

Presentamos el análisis de respuestas, de estudiantes de secundaria y de universidad a cuatro tareas que indagan cómo comprenden qué es un número en general y en particular un número irracional, el orden, la densidad y el supremo de un intervalo, en los números reales. Encontramos un gradiente de profundidad en sus ideas desde (i) una visión de los enteros como modelo de número, ajenidad o inseguridad frente a estos aspectos de R, principalmente en estudiantes con menor estudio de matemática. En una zona intermedia la (ii) concepción de los reales identificados con los decimales finitos y de una discretitud explícita, principalmente en estudiantes de secundaria y (iii) una visión en la cual se identifican a los reales con los racionales y como infinitos-potencialmente densos; presente principalmente en ingresantes a las carreras científicas. Por último y principalmente estudiantes avanzados de Matemática, que (iv) comprenden el orden, la densidad y propiedad del supremo en los reales. Mostramos que para promover que los/las estudiantes se apropien del número real, la enseñanza debe prever para los últimos años de secundaria y primeros de universidad trabajar sobre estas complejas nociones, de modo de facilitar el pasaje de una matemática escolar a una matemática avanzada.
PELATIHAN PENULISAN DRAF PROPOSAL PTK BAGI GURU BAHASA INDONESIA KELOMPOK MGMP SMP DI KABUPATEN REJANG LEBONG
Authors: Yulistio Didi 
Published: May 2022

Tujuan Kegiatan pengabdian pada masyarakat ini untuk memberikan pengalaman menulis proposal Penelitian Tindakan Kelas (PTK), khususnya, perubahan pola pikir (mindset) sikap, pengetahuan, dan keterampilan dalam menulis draf proposal PTK bagi guru Bahasa Indonesia Kelompok MGMP SMP N/S di Kabupaten Rejang Lebong. Kegiatan ini dilaksanakan di SMP Negeri 1 Rejang Lebong Jalan Basuki Rahmad No 06 Curup pada hari Rabu, 19 Februari 2020, Pukul 08.00 s.d 16.00 WIB., dengan peserta sebanyak 30 orang. Kegiatan ini menggunakan metode Bimbingan Teknis melalui ceramah, tanya jawab, diskusi terpimpin, dan demonstrasi praktis. Narasumber kegiatan dosen Prodi Pendidikan Bahasa Indonesia FKIP Universitas Bengkulu, dengan presentasi materi penulisan draf proposal PTK, mencakup judul, permasalahan PTK, Kerangka Teori, dan Metode Pelaksanaan PTK melalui tiga tahapan, yakni (1) perencanaan, (2) pelaksanaan, dan (3) evaluasi dan pelaporan hasil kegiatan. Target capaian kegiatan, yakni perubahan pola pikir sikap, pengetahuan, dan keterampilan guru bahasa Indonesia dalam menulis draf proposal PTK dan tersusunnya laporan hasil Pengabdian pada Masyarakat serta luaran berupa artikel Jurnal PPM. Hasil kegiatan pengabdian kepada masyarakat ini dapat disimpulkan bahwa kegiatan pelatihan telah mengubah pengetahuan dan keterampilan guru bahasa Indonesia dalam menulis draf proposal PTK secara baik dan bermakna. Terlihat dari keterampilan guru dalam merumuskan judul dan bagian permasalahan PTK. Pelatihan ini juga telah mengubah aktivitas pola pikir (mindset), khususnya sikap guru bahasa Indonesia yang menyatakan hasil kegiatan dalam menulis draf proposal PTK penting dan bermanfaat. Hal ini tampak dari aktivitas peserta yang bersemangat dalam mengikuti proses pembimbingan dan diskusi menyusun judul dan permasalahan PTK serta bukti hasil evaluasi yang secara umum menyatakan sangat bermanfaat. Harapan peserta, bahwa kegiatan ini perlu ada tindak lanjut, baik melalui bimtek mandiri secara online melalui WA, maupun kegiatan pelatihan lanjutan penyusunan kerangka teori dan metodologi penelitian hingga penelitian di kelas serta tersusunnya laporan PTK dan artikel untuk jurnal ilmiah.
Pengembangan Wisata Pantai Syari Untuk Meningkatkan Perekonomian Masyarakat Momi Waren Ransiki Papua Barat
Authors: Rombe Yunita Pare , Kaiba Abner Oskar , Marisan Hengki Marisan 
Published: May 2022

Pariwisata merupakan salah satu sektor pertumbuhan ekonomi yang terus berkembang untuk kesejahteraan masyarakat dan salah satu program unggulan dalam pembagunan daerah. Pembagunan pariwisata diharapakan dapat memberikan konstribusi terhadap pendapatan suatu daerah. Kabupaten Manokwari Selatan merupakan salah satu potensi wisata alam dan sejarah. Potensi pariwisata manokwari selatan dapat dimanfaatkan masyarakat dalam meningkatkan perekonomian bagi penduduk di wilayah sekitarnya. Potensi pariwisata tersebar di wilayah Ransiki, Nenei dan khususnya Momi Waren. Tujuan dari kegiatan ini adalah menata kawasan pantai syari Momi Waren dengan desain menarik dan pembuatan sarana prasarana dan meningkatkan perekonomian masyarakat.metode yang diguanakn yaitu observasi, sosialisasi, pelaksanaan dan evaluasi hasil program kegiatan.
Aplikasi Pemanfaatan Tepung Mocaf (Modified Cassava Flour) Pada Beberapa Produk Pangan Di Madrasah Aliyah Mambaul Ulum Kabupaten Bengkulu Tengah
Authors: Gusriani Ika , Koto Hidayat , Dany Yusril 
Published: May 2022

Tepung Mocaf ( Tepung Singkong Modifikasi) merupakan Ubi Kayu Yang Telah diubah sehingga menyerupai Karakter Tepung Terigu. Tepung Mocaf memiliki kadar air 9,25%, Kadar protein 1,93%, kadar abu 0,30%, kadar pati 85,60%, kadar lemak 2,72%, kadar serat 0,21%. Pengabdian ini bertujuan untuk memberikan sejumlah informasi dan sosialisasi Tepung Mocaf sebagai pengganti dari Tepung terigu, sehingga diharapkan mampu mengurangi penggunaan Tepung terigu di masyarakat; memberikan informasi kandungan nutrisi; memberikan edukasi dan demonstrasi penggunaan tepung Mocaf pada beberapa produk pangan olahan seperti bakso, Mie basah dan, Cookies, biskuit, dan terutama pada Brownies Rendah Gluten;mengedukasi siswa dan pelaku usaha di Sekolah terhadap peluang Usaha Pemanfaatan Ubi Kayu menjadi Tepung Mocaf dan aplikasi Tepung Mocaf pada beberapa produk pangan. Pengabdian dilakukan dengan cara koordinasi dan sosialisasi, penyuluhan dan demonstrasi secara langsung di Sekolah Madrasah Aliyah Mambaul Ulum dihadiri oleh sejumlah Guru dan murid yang juga sebagai pelaku wirausaha di Sekolah tersebut. Pengabdian tersebut berjalan dengan baik dan lancar, hal ini dapat dilihat dari antusiasme guru dan murid yang ikut pelaksanaan demo aplikasi Tepung Mocaf berlangsung. Pengabdian ini perlu dilanjutkan dengan memanfaatkan Tepung Mocaf yang diaplikasikan pada beberapa produk pangan lainnya sehingga dapat memaksimalkan penggunaan tepung Mocaf yang bersumber dari pangan lokal.
Edukasi Kesiap-Siagaan Bencana Tsunami Pada Anak Melalui Penggunaan Media Pembelajaran Interaktif
Authors: Pratama M. Iqbal Liayong , Yusuf Daud , Hendra Hendra 
Published: May 2022

Pelaksanaan pengabdian berfokus pada edukasi kesiap-siagaan bencana tsunami pada anak dikawasan pesisir Teluk Tomini sebagai langkah awal untuk pengurangan resiko bencana. Hal ini dilakukan berdasar pada upaya untuk mengurangi risiko bencana pada anak, yang mana anak-anak merupakan golongan yang rentan terhadap suatu bencana. Anak-anak perlu dibekali akan berbagai informasi mengenai bencana alam, tentu saja muatan informasi tersebut dan cara penyampaiannya perlu disesuaikan dengan usia mereka. Alternatif yang mudah dalam mengenalkan konsep bencana alam ialah melalui penggunaan media pembelajaran interaktif. Penggunaan media bertujuan untuk menarik minat anak untuk belajar dan memberikan kemudahan dalam menyajikan materi kepada anak. Pelaksanaan pengabdian edukasi kesiap-siagaan bencana tsunami pada anak menggunakan media interaktif ini menunjukkan hasil yang positif. Anak-anak lebih mengetahui tentang konsep dan penyebab dan tanda-tanda terjadinya bencana tsunami, serta tindakan-tindakan dalam menghadapi bencana tersebut. Selain itu, anak-anak bersedia untuk berbagi informasi kepada teman-teman dan keluarga tentang konsep bencana tsunami dan sikap kesia-siagaan dalam menghadapinya.
Solvent-Induced Selectivity of Isoprene From Bio-Derived Prenol
Authors: Kothandaraman Jotheeswari , Cosimbescu Lelia , Swita Marie S. 
Published: May 2022

In this work we demonstrate the selective catalytic conversion of prenol, which is an allylic alcohol that can be prepared from renewable resources to isoprene. The catalyst is an inexpensive molybdenum complex (Molyvan L) designed and used as an additive for lubricants. Isoprene is generated under relatively mild reaction parameters at 130–150°C, for 2 h, under vapor pressure conditions that do not exceed 50 psi. Two cases were studied: one in which Molyvan L was dissolved in a base oil at 1% concentration (weight/weight) and then mixed with a solvent and prenol and the other in which neat Molyvan L was introduced in the reaction and the base oil was replaced with the solvent and prenol. We investigated the selectivity of the reaction using the following solvents in both cases: dodecane, dodecanol, isododecane, octane, blendstock for oxygenate blending (BOB3), a fuel surrogate, a polyalphaolefin (PAO4), and methoxy polyethylene glycol (methoxy PEG350). Although conversion of prenol was above 94% in all experiments, isoprene was formed with various degrees of efficiency alongside a prenol isomeric alcohol, diprenyl ether and mixed ether via intramolecular and intermolecular dehydration reactions. Dodecane appeared to have the highest level of selectivity initially in base oil so we studied the effect of various dodecane-like solvents on isoprene yield and product profile. Surprisingly, octane (similar to dodecane) and isododecane (branched alkane) generated insignificant amounts of byproducts, essentially providing the highly desired isoprene with a very high selectivity. Branching of the solvent does not appear to have an effect on selectivity. Another advantage of this catalyst is the low loadings required to effect the transformation; that is, 0.25% (weight/volume) in the cases using neat Molyvan L and 0.5% (weight/volume) in the cases using Molyvan L dissolved in the base oil. Provided that prenol can be produced in large scale from bioresources, this work would enable the sustainable production of isoprene, in good yield, and with very high selectivity.
“Alterations in the Skin Microbiota Are Associated With Symptom Severity in Mycosis Fungoides”
Authors: Zhang Yumeng , Seminario-Vidal Lucia , Cohen Leah , Hussaini Mohammad , Yao Jiqiang , Rutenberg David , Kim Youngchul , Giualiano Anna , Robinson Lary A. , Sokol Lubomir 
Published: May 2022

Cutaneous T cell lymphoma (CTCL), a non-Hodgkin lymphoma, is thought to arise from mature tissue-resident memory T cells. The most common subtypes include Mycosis Fungoides and Sezary Syndrome. The role of skin microbiota remains unclear in the symptom manifestation of MF. Among 39 patients with MF, we analyzed bacteria colonizing MF lesions and non-lesional skin in the contralateral side and characterized regional changes in the skin microbiota related to MF involvement using the difference in relative abundance of each genus between lesional and contralateral non-lesional skin. We investigated the relationship between these skin microbiota alterations and symptom severity. No statistically significant difference was found in bacterial diversity and richness between lesional and non-lesional skin. Different skin microbiota signatures were associated with different symptoms. More pronounced erythema in the lesions was associated with an increase in Staphylococcus. Pain and thick skin in the lesions were associated with a decrease in Propionibacterium. The results of this pilot study suggest that the skin microbiota plays an important role in changing skin phenotypes among patients with MF. Larger skin microbiota studies are needed to confirm these findings and support the use of antibiotic treatment to mitigate CTCL symptoms.
Humoral, Cellular and Cytokine Immune Responses Against SARS-CoV-2 Variants in COVID-19 Convalescent and Confirmed Patients With Different Disease Severities
Authors: Chiu Chun-Hsiang , Chang Yu-Hsiu , Chang Feng-Yee , Hung Yi-Jen , Liao Ching-Len , Chiu Kuo-Chou , Tsai Pei-Ling , Chang Tien-Wei , Yen Li-Chen 
Published: May 2022

ObjectivesTo assess humoral and cellular immune responses against SARS-CoV-2 variants in COVID-19 convalescent and confirmed patients, to explore the correlation between disease severity, humoral immunity, and cytokines/chemokines in confirmed patients, and to evaluate the ADE risk of SARS-CoV-2.MethodsAnti-RBD IgG were quantified using an ELISA. Neutralization potency was measured using pseudovirus and real virus. Cellular immunity was measured using ELISpot. Cytokine/chemokine levels were detected using multiplex immunoassays. In vitro ADE assays were performed using Raji cells.ResultsOne-month alpha convalescents exhibited spike-specific antibodies and T cells for alpha and delta variants. Notably, the RBD-specific IgG towards the delta variant decreased by 2.5-fold compared to the alpha variant. Besides, serum from individuals recently experienced COVID-19 showed suboptimal neutralizing activity against the delta and omicron variants. Humoral immune response, IL-6, IP-10 and MCP-1 levels were greater in patients with severe disease. Moreover, neither SARS-CoV-1 nor SARS-CoV-2 convalescent sera significantly enhanced SARS-CoV-2 pseudovirus infection.ConclusionsSignificant resistance of the delta and omicron variants to the humoral immune response generated by individuals who recently experienced COVID-19. Furthermore, there was a significant correlation among disease severity, humoral immune response, and specific cytokines/chemokine levels. No evident ADE was observed for SARS-CoV-2.
Long-Term Beta-Blocker Therapy in Patients With Stable Coronary Artery Disease After Percutaneous Coronary Intervention
Authors: Lee Seung-Jun , Choi Dong-Woo , Kim Choongki , Suh Yongsung , Hong Sung-Jin , Ahn Chul-Min , Kim Jung-Sun , Kim Byeong-Keuk , Ko Young-Guk , Choi Donghoon , Park Eun-Cheol , Jang Yangsoo , Nam Chung-Mo , Hong Myeong-Ki 
Published: May 2022

BackgroundIt is unclear whether beta-blocker treatment is advantageous in patients with stable coronary artery disease (CAD) who underwent percutaneous coronary intervention (PCI). We evaluated the clinical impact of long-term beta-blocker maintenance in patients with stable CAD after PCI with drug-eluting stent (DES).MethodsFrom a nationwide cohort database, we identified the stable CAD patients without current or prior history of myocardial infarction or heart failure who underwent DES implantation. An intention-to-treat principle was used to analyze the impact of beta-blocker treatment on long-term outcomes of major adverse cardiovascular events (MACE) composed of cardiovascular death, myocardial infarction, and hospitalization with heart failure.ResultsAfter stabilized inverse probability of treatment weighting, a total of 78,380 patients with stable CAD was enrolled; 45,746 patients with and 32,634 without beta-blocker treatment. At 5 years after PCI with a 6-month quarantine period, the adjusted incidence of MACE was significantly higher in patients treated with beta-blockers [10.0 vs. 9.1%; hazard ratio (HR) 1.11, 95% CI 1.06–1.16, p &lt; 0.001] in an intention-to-treat analysis. There was no significant difference in all-cause death between patients treated with and without beta-blockers (8.1 vs. 8.2%; HR 0.99, 95% CI 0.94–1.04, p = 0.62). Statistical analysis with a time-varying Cox regression and rank-preserving structure failure time model revealed similar results to the intention-to-treat analysis.ConclusionsAmong patients with stable CAD undergoing DES implantation, long-term maintenance with beta-blocker treatment might not be associated with clinical outcome improvement.Trial RegistrationClinicalTrial.gov (NCT04715594).
Effect of Integrated Care on Patients With Atrial Fibrillation: A Systematic Review of Randomized Controlled Trials
Authors: Li Yi , Zhao Wenjing , Huang Jun , Zheng Murui , Hu Peng , Lu Jiahai , Deng Hai , Liu Xudong 
Published: May 2022

AimsThe integrated management was evidenced to improve the hospitalization and its associated complications in patients with atrial fibrillation (AF), but the strategies of integrated care varied and results were inconsistent. This systematic review and meta-analysis aimed to evaluate the effect of integrated care on AF-related outcomes with comparison with usual care.MethodsPubMed, Embase, and Web of Science were searched for articles published until 10th January 2022. Eligible studies were randomized controlled trials to study the effect of integrated care on AF-related outcomes. Meta-analysis with a random-effect model was used to calculate risk ratio (RR) and 95% confidence interval (CI) by comparing the integrated care with usual care.ResultsA total of five studies with 6,486 AF patients were selected. By synthesizing available data, integrated care effectively reduced the risk of all-cause mortality (RR = 0.54, 95% CI = 0.42–0.69), cardiovascular hospitalization (RR = 0.72, 95% CI = 0.55–0.94), and cardiovascular mortality (RR = 0.52, 95% CI = 0.36–0.78) when compared with usual care; however, there was no superior effect on preventing AF-related hospitalization (RR = 0.86, 95% CI = 0.72–1.02), cerebrovascular events (RR = 1.13, 95% CI = 0.75–1.70), and major bleeding (RR = 1.29, 95% CI = 0.86–1.94) when comparing integrated care with usual care.ConclusionIntegrated care can reduce the risk of all-cause mortality, cardiovascular mortality, and cardiovascular hospitalizations in AF patients compared with usual care, while the benefit was not observed in other outcomes.
Geological and Geochemical Characteristics of the Terrestrial Lower Jurassic Shale in Tarim Basin and its Favorable Exploration Areas
Authors: Wang Qifeng , Tang Haifa , Guo Zhi , Cheng Gang , Lv Zhikai , Liu Qunming 
Published: May 2022

Large amounts of conventional gas resources that originated from terrestrial Lower Jurassic shale were discovered in the Tarim Basin, indicating promising exploration prospects for shale gas resources, whereas limited understandings were obtained on the geological and geochemical characteristics of the Lower Jurassic shale. In this study, based on cores of exploration wells and field outcrops, total organic carbon (TOC) pyrolysis, microscopic composition, organic elements, vitrinite reflectance, x-ray diffraction, and methane isothermal adsorption experiments were carried out on Lower Jurassic shale in the Tarim Basin. The results show that the TOC content of shale is relatively high, but the TOC content of shale in different regions is quite different. Among them, the Kuqa Depression is the highest (more than 3%), the Southwest Tarim Basin is second (more than 1%), and the East Tarim Basin is the lowest. The main types of kerogen in shale are mainly type III and type II2. The thermal evolution maturity of shale in different regions is quite different; the highest Ro of shale in the Southwest Tarim Basin is more than 2.0% and that of shale in the Kuqa depression is higher than 1.5%, both of which have entered the stage of high-over-mature evolution, and the shale in the East Tarim Basin is only in the low maturity–mature stage. The overall content of brittle minerals such as quartz in shale is greater than 40%, which has good fracturing properties. The adsorbed gas content of shale is high, but there is a great difference (0.5–4 m3/t), which is related to the large difference in the abundance of organic matter, thermal maturity, and clay mineral content of shale. Therefore, the Lower Jurassic shale gas in the Tarim Basin has good prospects for exploration. Based on the superposition method of the main controlling geological factors, it is predicted that the favorable areas for shale gas exploration are mainly located in the Keshen and Yinan-Yeyun areas of the Kuqa Depression and the Caohu Sag-Mandong area of the East Tarim Basin. This research not only provides basic data for the evaluation of shale gas resources in our country, but also provides certain guidance for the exploration of Lower Jurassic shale gas in the Tarim Basin.