bluuebunny/crossref_metadata_2025_split huggingface dataset:
Schistosoma mansoni miracidia: revisiting motility and survival parameters for improved computational modelling
Authors: de Souza Renata Perotto , Pascoal Vanessa Fey , Vilches Thomas Nogueira , Bittencourt Hélio Radke , Utz Laura Roberta Pinto , Graeff-Teixeira Carlos 
Published: May 2022

AbstractSchistosoma mansoni is the main causative agent of intestinal schistosomiasis which affects millions of people worldwide. At the larval stage, miracidia are released into bodies of water where they utilize their motility to successfully infect their intermediate host, snails. Here, we revisit the motility and survival of S. mansoni miracidia throughout its life span. Briefly, miracidia motility was monitored at 30-min and 60-min intervals under the presence/absence of natural/artificial light. Based on a subjective evaluation of activity, body shape and transparency, 6 categories of miracidia activity were established from its fully active stage to its immobile larva stage. The estimated life span of miracidia was 5.8 and 3.5 h in the experiments with 60-min and 30-min observation intervals, respectively. Death was defined by an absence of cilia and body movement. When mobility was used as a proxy for infectivity, infective miracidia were detected at 2.5 and 4.5 h, respectively. The present miracidia motility and survival re-evaluation supports parameters optimization for computational modelling of schistosomiasis transmission dynamics. Target control interventions, especially at late stages next to transmission interruption, may greatly benefit from improved modelling studies.
Haemosporidian infections in wild populations of Podarcis muralis from the Italian Peninsula
Authors: Storniolo Federico , Zuffi Marco A. L. , Coladonato Alan J. , Mangiacotti Marco , Scali Stefano , Sacchi Roberto 
Published: May 2022

AbstractParasites can significantly influence the ecology, behaviour and physiology of their hosts sometimes with remarkable effects on their survivorship. However, endemic parasites or those not associated with obvious clinical disease have been partly neglected in the past decades comparatively to the most pathogenic ones. Apicomplexa are an important example of blood parasites that have been broadly investigated, although it can be difficult to determine the effects of infections at the population level, especially in widespread species. Such is the case of the common wall lizard (Podarcis muralis). We investigated 61 populations across Italy between 2008 and 2017 and recorded snout–vent length, latitude, date of collection and took blood samples for parasite count. We modelled parasite prevalence and load in a Bayesian framework. Parasites were present in all populations but 1 and in 13 of them all individuals were parasitized. We recorded almost identical responses for probability of infection and parasite load in both sexes, directly proportional to body size and inversely proportional to latitude, with a peak in cooler months. Therefore, haemosporidians can be very common in P. muralis, although their presence can vary significantly. Moreover, such a high prevalence makes it necessary to investigate to what extent haemosporidians affect hosts' survivorship, taking into consideration abiotic and biotic factors such as temperature, hormone levels and immune response.
Effects of nest-box environment on fledgling success rate and pathogen load
Authors: Scott-Baumann James F. , Morgan Eric R. , Cogan Tristan A. 
Published: May 2022

AbstractNest boxes have been used for many decades as tools for conservation and to study avian population dynamics. Plastic is increasingly used as a material for nest boxes, but no studies have investigated effects of this different material. Two consecutive studies were conducted to investigate effects of nest-box environment on nidicolous parasites, bacteria and fungi, as well as nest success, in blue tits Cyanistes caeruleus and great tits Parus major. The first compared microclimate and parasite and pathogen load in plastic and wooden nest boxes. The second tested the nest protection hypothesis – that birds naturally incorporate aromatic herbs into nests to decrease nest parasites and pathogens – by comparing parasite and pathogen load in plastic nest boxes to which aromatic or non-aromatic plant material was added. No significant difference in nest-box temperature or relative humidity was found between plastic and wooden boxes. Wooden boxes, however, contained 30-fold higher numbers of fleas and a higher total bacterial load on chicks. Fledging success for blue tit broods was significantly higher in wooden boxes. Parasites and bacteria did not decrease by the inclusion of aromatic herbs. The results increase the evidence base for nest-box design in support of plastic, which can provide an appropriate alternative nest-box material to wood, with apparently no difference in microclimate and no increase in the load of measured parasites and pathogens.
The relation of second language acquisition, instructed second language acquisition, and language teaching from the lens of second language tense-aspect
Authors: Bardovi-Harlig Kathleen , Comajoan-Colomé Llorenç 
Published: May 2022

AbstractThis article examines the relationships between second language acquisition (SLA), instructed second language acquisition (ISLA), and language teaching by examining them from the lens of the research on the acquisition and teaching of second language (L2) tense-aspect in the last 20 years (2000–2021). Review 1 examines 56 instructional effect studies on the acquisition of L2 tense-aspect, and Review 2 examines 38 pedagogical proposals for the teaching of L2 tense-aspect. The reviews investigate to what extent instructional effect studies and pedagogical proposals with tense-aspect as the target of investigation and instruction (a) provide a linguistic description of the instructional target, (b) engage with previous research, (c) implement results from previous research to design assessment or instruction, and (d) include elaborate descriptions of teaching interventions and teaching materials. The results show that there are clear attempts to establish connections between research and practice. However, neither instructional effect studies nor pedagogical proposals always engage with the SLA literature on the acquisition of tense-aspect; nor do they engage fully with language teaching.
Diversity patterns of lizard assemblages from a protected habitat mosaic in the Brazilian Cerrado savanna
Authors: Barros Rafael Assis , Dorado-Rodrigues Tainá Figueras , Valadão Rafael Martins , Strüssmann Christine 
Published: May 2022

AbstractDifferences in habitat complexity and structure can directly influence the composition, diversity, and structure of species assemblages. Measurements of functional and phylogenetic diversity complement the commonly used measurements of taxonomic diversity, elucidating the relationships between species, their traits, and their evolutionary history. In this study, we evaluated how the mosaic of open and forested formations in a federal conservation unit in the western portion of the Brazilian Cerrado savanna influences the taxonomic, functional, and phylogenetic structure of lizard assemblages. Lizards were sampled for 15 months using pitfall traps set in open and forested formations. We recorded 292 lizards distributed among 16 species from eight families, with species composition differing among the formations. Richness was greater in the assemblages from open formations, while functional diversity and phylogenetic variability were greater in those of forested formations. Lizard assemblages in open formations were functionally and phylogenetically clustered, probably as a result of environmental filters acting on species, while the assemblages from forested formations were randomly structured. Different environmental and historical mechanisms have apparently shaped the current diversity of lizards in the region. This study shows that Cerrado vegetation mosaics can promote wide variation in different aspects of the taxonomic, functional, and phylogenetic structure from the lizard assemblages.
Evaluation of the left ventricular systolic function and myocardial deformation by real-time three-dimensional (four-dimensional) and speckle-tracking echocardiography in children with type 1 diabetes mellitus
Authors: Eroğlu Ayşe G. , Yüksel Esra K. , Karagözlü Fatih , Acar Hazal C. , Gökalp Selman , Evliyaoğlu Olcay 
Published: May 2022

AbstractAim:This study aimed to evaluate the role of real-time three-dimensional (known as four-dimensional) echocardiography and three-dimensional speckle-tracking echocardiography for the early detection of left ventricular systolic dysfunction in asymptomatic children with type 1 diabetes mellitus.Materials and method:This cross-sectional study included 38 patients (mean age 15.4 ± 2.9, 42.1% male) and 38 age, gender, and body measurements matched healthy children. Each patient underwent an interview about medical history, a detailed clinical examination, blood laboratory tests, conventional echocardiography, and tissue Doppler imaging. Left ventricular ejection fraction; global longitudinal, circumferential, radial strain; twist; and torsion were measured by real-time three-dimensional and speckle-tracking echocardiography.Results:Conventional echocardiography and tissue Doppler imaging showed normal left ventricular systolic function in the patients. Although left ventricular ejection fraction (61.6 ± 1.4%, 61.8 ± 1.1%, p = 0.386), global longitudinal [−26.6 (−27.7 to −26.1)%, −26.2 (−27.7 to −24.9)%, p = 0.224], and radial strain [44.4 (42.4–45.9)%, 43.9 (41–46.1)%, p = 0.513] were similar to the controls, circumferential strain (−27.3 ± 1.3%, −28.0 ± 1.6%, p = 0.048) and twist (9.5 ± 2.3°, 11.4 ± 3.0°, p = 0.003) were decreased in the patients compared with controls.Conclusion:We found that even in children with asymptomatic type 1 diabetes mellitus with normal left ventricular ejection fraction, circumferential function was impaired and rotation pattern was changed. This novel echocardiographic method might be an important tool for detecting left ventricular systolic dysfunction in type 1 diabetes mellitus children before it becomes overt on conventional echocardiography and tissue Doppler imaging.
Performance of a single-ventricle home-monitoring programme: survival and predictors of adverse outcome
Authors: Lillitos Peter J. , Rittey Leila , Vass Madeleine , Ugwoke Gerald , Akhtar Muhammad , Barwick Shuba , Van Doorn Carin , Jaber Osama , Bentham James R. 
Published: May 2022

AbstractIntroduction and background:Mortality between stages 1 and 2 single-ventricle palliation is significant. Home-monitoring programmes are suggested to reduce mortality. Outcomes and risk factors for adverse outcomes for European programmes have not been published.Aims:To evaluate the performance of a home-monitoring programme at a medium-sized United Kingdom centre with regards survival and compare performance with other home-monitoring programmes in the literature.Methods:All fetal and postnatal diagnosis of a single ventricle were investigated with in-depth analysis of those undergoing stage 1 palliation and entered the home-monitoring programme between 2016 and 2020. The primary outcome was survival. Secondary outcomes included multiple parameters as potential predictors of death or adverse outcome.Results:Of 217 fetal single-ventricle diagnoses during the period 2016–2020, 50.2% progressed to live birth, 35.4% to stage 1 and 29.5% to stage 2. Seventy-four patients (including 10 with postnatal diagnosis) entered the home-monitoring programme with six deaths making home-monitoring programme mortality 8.1%. Risk factors for death were the hybrid procedure as the only primary procedure (OR 33.0, p < 0.01), impaired cardiac function (OR 10.3, p < 0.025), Asian ethnicity (OR 9.3, p < 0.025), lower mean birth-weight (2.69 kg versus 3.31 kg, p < 0.01), and lower mean weight centiles during interstage follow-up (mean centiles of 3.1 versus 10.8, p < 0.01)Conclusion:Survival in the home-monitoring programme is comparable with other home-monitoring programmes in the literature. Hybrid procedure, cardiac dysfunction, sub-optimal weight gain, and Asian ethnicity were significant risk factors for death. Home-monitoring programmes should continue to raise awareness of these factors and seek solutions to mitigate adverse events. Future work to generalise home-monitoring programme and single-ventricle fetus to stage 2 outcomes in the United Kingdom will require multi-centre collaboration.
Multilevel exploration of individual- and community-level factors contributing to overweight and obesity among reproductive-aged women: a pooled analysis of Bangladesh Demographic and Health Survey, 2004–2018
Authors: Ahammed Benojir , Sarder Md. Alamgir , Kundu Subarna , Keramat Syed Afroz , Alam Khorshed 
Published: May 2022

AbstractObjectives:Overweight and obesity have been related to a variety of adverse health outcomes. Understanding the overweight and obesity epidemic in Bangladesh, particularly among reproductive-aged women, is critical for monitoring and designing effective control measures. The purpose of this study was to determine the prevalence of overweight and obesity in reproductive-aged women and to identify the risk factors of overweight and obesity.Design:A total of 70 651 women were obtained from the five most recent and successive Bangladesh Demographic and Health Surveys (BDHS). The multilevel logistic regression model was used to explore the individual- and community-level factors of overweight and obesity.Setting:Five most recent nationally representative household surveys across all regions.Participants:Reproductive-aged (15–49 years) non-pregnant women.Results:Approximately 35·2 % (95 % CI: 34·9–35·6 %) of women were either overweight or obese in Bangladesh. At the individual- and community-level, higher age (adjusted odds ratio (aOR) = 5·79, 95 % CI: 5·28–6·34), secondary or higher education (aOR = 1·69 [1·60–1·78]), relatively wealthiest households (aOR = 4·41 [4·10–4·74]), electronic media access (aOR = 1·32 [1·26–1·37]) and community high literacy (aOR = 1·10 [1·04–1·15]) of women were significantly positively associated with being overweight or obese. Whereas, rural residents (aOR = 0·79 [0·76–0·82]) from larger-sized households (aOR = 0·80 [0·73–0·87]) and have high community employment (aOR = 0·92 [0·88–0·97]) were negatively associated with the probability of being overweight or obese.Conclusion:Individual- and community-level factors influenced the overweight and obesity of Bangladeshi reproductive-aged women. Interventions and a comprehensive public health plan aimed at identifying and addressing the growing burden of overweight and obesity should be a top focus.
Temporal patterns of sleep and eating among children during school closure in Japan due to COVID-19 pandemic: associations with lifestyle behaviours and dietary intake
Authors: Sugimoto Minami , Murakami Kentaro , Sasaki Satoshi 
Published: May 2022

AbstractObjective:To identify temporal patterns of sleep and eating among school-age children during school closure due to the COVID-19 pandemic and to examine their associations with lifestyle behaviours and dietary intake.Design:In this cross-sectional study, questionnaires were used to assess sleep and eating times, lifestyle behaviours and dietary intake during school closure. Latent class analysis was performed to identify temporal patterns of sleep and eating based on self-reported clock times for wake-up, going to bed and eating meals. Lifestyle behaviours and dietary intake were compared between latent classes.Setting:Forty-eight primary and secondary schools in Japan.Participants:Totally, 6220 children (aged 8–15 years).Results:Four patterns, labelled ‘Very early (20 % of children)’, ‘Early (24 %)’, ‘Late (30 %)’ and ‘Very late (26 %),’ were identified and ordered according to the circadian timing. Latter patterns were characterised by later timings of sleep and eating, especially in clock times for wake-up, breakfast and lunch compared with earlier patterns. Children with latter patterns had a less physically active lifestyle, longer screen time (≥4 h/d), shorter study time (<2 h/d) and more frequent skipping of breakfast and lunch than those with earlier patterns. In addition, children with latter patterns had lower intakes of several vitamins, vegetables, fruits, fish and shellfish and dairy products and higher intakes of sugar and confectionaries and sweetened beverages.Conclusion:More than half of the participants had later wake-up, breakfast and lunch during school closure, which was associated with more unfavourable lifestyles and dietary intakes.
Rural disparities in head and neck cancer from 2017 to 2021: a single institution analysis
Authors: Nguyen My-Lien , Derouen Jonathan T. , Cantrell J. Nathan , Johnston Andrea , Vidal Gabriel , Schutz Alexis , Ogilvie William , Businelle Michael , Ahmad Salahuddin , Henson Christina 
Published: May 2022

Abstract

Introduction:
This study aims to look at the trends in our head and neck cancer patient population over the past 5 years with an emphasis on the past 2 years to evaluate how the coronavirus disease 2019 (COVID-19) pandemic has impacted our disparities and availability of care for patients, especially those living in rural areas. An additional aim is to identify existing disparities at our institution in the treatment of head and neck patients and determine solutions to improve patient care.

Materials and Methods:
A retrospective chart review was performed to identify patients who were consulted and subsequently treated with at least one fraction of radiation therapy at our institution with palliative or curative intent. Patient demographic information was collected including hometown, distance from the cancer centre based on zip-codes and insurance information and type of appointment (in-person or telehealth). Rural–urban continuum codes were used to determine rurality.

Results:
A total of 490 head and neck cancer patients (n = 490) were treated from 2017 to 2021. When broken down by year, there were no significant trends in patient population regarding travel distance or rurality. Roughly 20–30% of our patients live in rural areas and about 30% have a commute > 50 miles for radiation treatment. A majority of our patients rely on public insurance (68%) with a small percentage of those uninsured (4%). Telehealth visits were rare prior to 2019 and rose to 5 and 2 visits in 2020 and 2021, respectively.

Conclusions:
Head and neck cancer patients, despite rurality or distance from a cancer centre, may present with alarmingly enough symptoms despite limitations and difficulties with seeking medical attention even during the COVID-19 pandemic in 2020. However, providers must be aware of these potential disparities that exist in the rural population and seek to address these.
What is IHL history now?
Authors: van Dijk Boyd 
Published: May 2022

AbstractOver the last few decades, an extraordinary amount has changed in our understanding of the history of international humanitarian law (IHL). This article addresses the latest findings in this new historiography, placing contemporary IHL issues in a broader historical context and sharing the author's own experiences as a researcher exploring the discipline's practice from a historical perspective. Ultimately, he makes a passionate case for history – by showing why this discipline has a lot to offer for practitioners of international law.
Climate Controls on River Chemistry
Authors: Li Li , Stewart Bryn , Zhi Wei , Sadayappan Kayalvizhi , Ramesh Shreya , Kerins Devon , Sterle Gary , Harpold Adrian , Perdrial Julia 
Published: May 2022

AbstractHow does climate control river chemistry? Existing literature has examined extensively the response of river chemistry to short‐term weather conditions from event to seasonal scales. Patterns and drivers of long‐term, baseline river chemistry have remained poorly understood. Here we compile and analyze chemistry data from 506 minimally impacted rivers (412,801 data points) in the contiguous United States (CAMELS‐Chem) to identify patterns and drivers of river chemistry. Despite distinct sources and diverse reaction characteristics, a universal pattern emerges for 16 major solutes at the continental scale. Their long‐term mean concentrations (Cm) decrease with mean discharge (Qm), with elevated concentrations in arid climates and lower concentrations in humid climates, indicating overwhelming regulation by climate compared to local Critical Zone characteristics such as lithology and topography. To understand the CmQm pattern, a parsimonious watershed reactor model was solved by bringing together hydrology (storage–discharge relationship) and biogeochemical reaction theories from traditionally separate disciplines. The derivation of long‐term, steady state solutions lead to a power law form of CmQm relationships. The model illuminates two competing processes that determine mean solute concentrations: solute production by subsurface biogeochemical and chemical weathering reactions, and solute export (or removal) by mean discharge, the water flushing capacity dictated by climate and vegetation. In other words, watersheds function primarily as reactors that produce and accumulate solutes in arid climates, and as transporters that export solutes in humid climates. With space‐for‐time substitution, these results indicate that in places where river discharge dwindles in a warming climate, solute concentrations will elevate even without human perturbation, threatening water quality and aquatic ecosystems. Water quality deterioration therefore should be considered in the global calculation of future climate risks.
A Novel Proxy for Tracking the Provenance of Dust Based on Paired E1’‐Peroxy Paramagnetic Defect Centers in Fine‐Grained Quartz
Authors: Dave Aditi K. , Timar‐Gabor Alida , Kabacińska Zuzanna , Scardia Giancarlo , Safaraliev Nosir , Nigmatova Saida , Fitzsimmons Kathryn E. 
Published: May 2022

AbstractCrystal lattice defects in quartz have long been exploited for age determination, yet also show potential for sediment provenance studies. Here, we introduce a novel method for tracking aeolian dust provenance by utilizing the natural accumulation of E1’ and peroxy defect centers in quartz. Our approach is based on the previously observed premise that E1’ and peroxy centers arise from Frenkel defect pairs, and that their concentration increases with the age of the quartz‐bearing source rock. We propose that these defect centers can be utilized as a characteristic feature of the source rock and consequently, for fingerprinting sediments derived from it. We successfully apply our new protocol to distinguish fine‐grained quartz extracted from loess deposits from two regions in Central Asia which are known to derive from different source material of differing age. Our method offers strong potential for identifying variability in source, both spatially and through time down sedimentary sequences.