bluuebunny/crossref_metadata_2025_split huggingface dataset:
Memory B cell responses to Omicron subvariants after SARS-CoV-2 mRNA breakthrough infection
Authors: Wang Zijun , Zhou Pengcheng , Muecksch Frauke , Cho Alice , Tanfous Tarek Ben , Canis Marie , Witte Leander , Johnson Brianna , Raspe Raphael , Schmidt Fabian , Bednarski Eva , Silva Justin Da , Ramos Victor , Zong Shuai , Turroja Martina , Millard Katrina G. , Yao Kai-Hui , Shimeliovich Irina , Dizon Juan , Kaczynska Anna , Jankovic Mila , Gazumyan Anna , Oliveira Thiago Y. , Caskey Marina , Gaebler Christian , Bieniasz Paul D. , Hatziioannou Theodora , Nussenzweig Michel C. 
Published: August 2022

AbstractIndividuals that receive a 3rd mRNA vaccine dose show enhanced protection against severe COVID19 but little is known about the impact of breakthrough infections on memory responses. Here, we examine the memory antibodies that develop after a 3rd or 4th antigenic exposure by Delta or Omicron BA.1 infection, respectively. A 3rd exposure to antigen by Delta breakthrough increases the number of memory B cells that produce antibodies with comparable potency and breadth to a 3rd mRNA vaccine dose. A 4th antigenic exposure with Omicron BA.1 infection increased variant specific plasma antibody and memory B cell responses. However, the 4th exposure did not increase the overall frequency of memory B cells or their general potency or breadth compared to a 3rd mRNA vaccine dose. In conclusion, a 3rd antigenic exposure by Delta infection elicits strain-specific memory responses and increases in the overall potency and breadth of the memory B cells. In contrast, the effects of a 4th antigenic exposure with Omicron BA.1 is limited to increased strain specific memory with little effect on the potency or breadth of memory B cell antibodies. The results suggest that the effect of strain-specific boosting on memory B cell compartment may be limited.
A genome catalogue of lake bacteria across watershed land use gradients at a continental scale
Authors: Garner Rebecca E. , Kraemer Susanne A. , Onana Vera E. , Fradette Maxime , Varin Marie-Pierre , Huot Yannick , Walsh David A. 
Published: August 2022

AbstractLakes are heterogenous ecosystems inhabited by a rich microbiome whose genomic diversity is poorly defined. We present a continental-scale study of metagenomes representing 6.5 million km2of the most lake-rich landscape on Earth. Analysis of 308 Canadian lakes resulted in a metagenome-assembled genome (MAG) catalogue of 1,008 mostly novel bacterial genomospecies. Lake trophic state was a leading driver of taxonomic and functional diversity among MAG assemblages, reflecting the responses of communities profiled by 16S rRNA amplicons and gene-centric metagenomics. Coupling the MAG catalogue with watershed geomatics revealed terrestrial influences of soils and land use on assemblages. Agriculture and human population density were drivers of turnover, indicating detectable anthropogenic imprints on lake bacteria at the continental scale. The sensitivity of bacterial assemblages to human impact reinforces lakes as sentinels of environmental change. Overall, the LakePulse MAG catalogue greatly expands the freshwater genomic landscape, advancing an integrative view of diversity across Earth’s microbiomes.
Being a college student leader boosts career prospects: a panel survey in China
Authors: Cui Sheng , Wu Qiuxiang , Erdemir Burcu 
Published: August 2022

PurposeThe authors explored the effect of college student leader experience on students' employment prospects, such as their starting salary. The authors also examined the factors behind being a student leader and the set of skills that foster the effect of leadership experience.Design/methodology/approachUsing an empirical panel survey, the authors collected data from 3,361 undergraduate students over five consecutive years in China, which were analysed using different econometric methods.FindingsThe starting salary premium associated with student leaders' experiences was approximately 7%. Individual learning, problem-solving, and interpersonal skills were mediating variables that replaced half of the wage premium effect of the student leader. Family background and types of educational experiences were associated with being a student leader and labour market outcomes.Research limitations/implicationsThe authors only explored a few leadership-related employability skills; other relevant skills require consideration.Practical implicationsThis study informs students, parents, and higher education institutions (HEIs) by clarifying the importance of leadership development. An effective transition from higher education to the labour market should be emphasised.Social implicationsHigher education educators should provide guidance to student organisations and promote formal and informal student leadership education to all students.Originality/valueThe authors revealed some factors that promote student leadership and how they are associated with labour market outcomes in China. The authors also verified and validated the capital improvement channel for some specific leadership-related skills to explain the effect of student leader experience on employment outcomes.
Sustainable menstrual products: a classic or a fad?
Authors: Ahuja Prerna , Singh Navjit 
Published: August 2022

Purpose
This all-inclusive bibliometric study aims to highlight the importance and shift of the researchers and the society towards the sustainable menstrual products (SMPs). This study also provides insights for this taboo topic which needs to be addressed for improving the menstrual hygiene of women.

Design/methodology/approach
This study adopts a trio of systematic literature review, bibliometric analysis and content analysis of the research articles taken from the SCOPUS database. The influential journals, authors and countries were established with the bibliometric analysis. Most prestigious research articles were identified based on the page-rank analysis. The intellectual structure was established with bibliographic coupling through which various themes were identified. For the content analysis, thematic mapping and author keyword analysis was performed to gain deeper understanding of themes.

Findings
It was established that the taboo yet novel research domain of SMPs is a necessary step towards the improvement of hygiene of women as well as the economy. The products are here to stay making them a Classic; hence, more research normalizing their usage is necessary. From this analysis, research gaps providing directions to the researchers were identified.

Originality/value
To the best knowledge of the authors, this is the first study that provides a comprehensive review of the SMPs. The research methodology applied in this review involves the triad of systematic literature review, bibliometric and content analyses study that establishes an intellectual structure and provides an all-inclusive overview of this taboo research area.
Labour market dualization and social policy in pandemic times: an in-depth analysis of private consumption services in Europe
Authors: Pavolini Emmanuele , Fullin Giovanna , Scalise Gemma 
Published: August 2022

PurposeThis article contributes to the debate on how social policies and labour market regulation have been used to limit the socio-economic consequences of the pandemic by focusing on one specific economic segment of European labour markets: private consumption services, such as trade, tourism, catering and other support services.Design/methodology/approachThe analysis combines mixed methods and a variety of sources. First, we built a set of indicators from the EU-LFS microdata for 2019 and the 2018 Eurostat “Structure of earnings survey” and performed a cluster analysis (k-means) on the dimensions and indicators considered. Second, we elaborated EU-LFS data covering 2019 and 2020 (by quarter) and OECD 2020 data, and finally we traced Covid-related policy reforms for the period March 2020–December 2021 and analysed documents and information collected in different policy repositories.FindingsThe paper shows the relevance and characteristics of private consumption services in different countries, demonstrating that so-called labour market “outsiders” are highly represented in this sector and illustrates the policies adopted to respond to the pandemic in different European countries. The paper asks whether this emergency has been a window of opportunity to redefine regulation in this sector, making it more inclusive. It demonstrates, however, that the common approach in Europe has been dominated by temporary, short-term and one-off measures, which do not represent major changes to the social security schemes that were in place before the pandemic.Originality/valueThis article builds on the literature on labour market dualization, but approaches the concept from a different perspective – one not centred on the nature of employment relations (stable/unstable) but on economic sectors/branches. This article does not, therefore, discuss in general terms what happened to labour market outsiders during the pandemic, but rather focus attention on a specific group of workers who are highly exposed to risks stemming from dualization: those employed in the private consumption services. The economic sector perspective is an integrative way of framing dualization which is still under-researched.
Corporate disclosure timing under IFRS: the case of emerging Georgia
Authors: Pirveli Erekle 
Published: August 2022

Purpose
This study aims to examine the timing of corporate disclosure in the context of Georgia, an emerging market where a recent reform of corporate financial transparency mandated about 80,000 private sector entities to publicly disclose their annual financial statements.

Design/methodology/approach
The main analysis covers more than 4,000 large, medium, small and micro private sector entities, for which the data is obtained from the Ministry of Finance of Georgia. This paper builds an empirical model of logit/probit regression, with industry fixed and random effects to investigate the drivers of the corporate disclosure timing.

Findings
Findings suggest that the mean reporting time lag is 279 days after the fiscal year-end, that is nine days after the statutory deadline. Almost one-third (30%) of the entities miss the nine-month statutory deadline, while the timely filers almost unexceptionally file immediately before the deadline. Multivariate tests reveal that voluntarily filing entities completed the process significantly faster than those mandated to do so; audited financial statements take more time to be filed, whereas those with unqualified audit opinion or audited by large/international audit firms are filed faster than their counterparts. The author concludes that despite the overall high filing rates, the timing of corporate disclosure is not (yet) efficiently enforced in practice (but is progressing over time), whereas regulatory incentives prevail over market incentives among the timely filers.

Originality/value
To the best of the author’s knowledge, this is the first study that explores corporate disclosure timing incentives in the context of Georgia. This study extends prior literature on the timing of financial information from an emerging country’s private sector perspective, with juxtaposed market and regulatory incentives.
Employee burnout: the dark side of performance-driven work climates
Authors: Fastje Franzisca , Mesmer-Magnus Jessica , Guidice Rebecca , Andrews Martha C. 
Published: August 2022

PurposeThe purpose of this study is to explore the role of “overtime norms” as a mediator between performance-driven work climates and employee burnout. This study also examines in-role performance and work engagement as moderators between high-performance climates and burnout.Design/methodology/approachA snowball sample of 214 full-time working adults from the United States participated via an online survey. Data were analyzed using SmartPLS and conditional process analysis.FindingsResults from conditional process analyses suggest (1) performance-driven climates are positively related to burnout, (2) overtime norms mediate the relationship between performance-driven climates and burnout, and (3) in-role performance and work engagement moderate that relationship such that highly competent and engaged employees are less prone to stress and burnout.Practical implicationsThese results highlight the dangers of performance-driven work climates on employee well-being. Trends toward extended work hours which can be exacerbated by technological advancements inevitably come at a cost. Managers and organizations should be careful not to prioritize work life over non-work life.Originality/valueThis study contributes to the literature by identifying overtime norms as a mediator in the performance-driven work climate–burnout relationship. This study also identifies in-role performance and work engagement as resources that can reduce burnout.
The impact of debt, taxation and financial crisis on earnings management: the case of Greece
Authors: Mamatzakis Emmanuel , Pegkas Panagiotis , Staikouras Christos 
Published: August 2022

PurposeThe purpose of this study is to empirically investigate the Greek firms' earnings management policies compared with debt, taxation and the financial crisis.Design/methodology/approachIn this paper, the authors show that existed measures of real earnings management, whether corrected for performance or not, rely crucially on strong assumptions. The authors provide a novel modelling that permits panel structure so as to correct for heterogeneity across firms while permitting to determine endogenously the number of underlying firm-groups in the data generating process.FindingsThe empirical results indicate that Greek firms are likely to reduce earnings manipulation activities when they face liquidity risk. Taxation and financial crisis have a negative and positive effect on earnings management, respectively.Originality/valueThe effect of debt, taxation and financial crisis on earnings management has never been investigated in Greece. The empirical results offer valuable information to shareholders and investors as they can understand how some main factors, such as debt, taxation and financial crisis, influence firm's accounting practices.
Clinical history analysis of Japanese melanoma cases and characteristics of melanoma with childhood onset
Authors: Minagawa Akane , Uhara Hisashi , Ashida Atsuko , Koga Hiroshi , Okuyama Ryuhei 
Published: August 2022

AbstractIt remains debatable whether melanoma with a clinical history of early childhood onset truly arises from a nevus. To clarify the clinical and genetic characteristics of melanoma detected at birth or several years afterwards, 249 melanoma cases seen at Shinshu University Hospital between 2006 and 2015 were retrospectively analyzed. Ten (4.0%) cases (median age 39.5 years, range 19–70 years; male/female 2/8; lesion site, 6 extremities, 2 trunk, 1 head, 1 face; cumulative sun damage [CSD] skin, 9 low‐CSD, 1 high‐CSD; detection at birth 3) had recorded early childhood onset. Median Breslow's tumor thickness in those cases was 6.0 mm (range: 0.4–17.5 mm). The frequency of lesions detected at <20 years of age was significantly higher for low‐CSD melanoma (17.5%) than for high‐CSD (3.3%) and acral (0.8%) melanoma. Although melanoma with a history of early childhood onset is rare, the characteristics of such cases should be established since most have progressed to an advanced stage at the initial visit.
Nonstructural carbohydrates predict survival in saplings of temperate trees under carbon stress
Authors: Piper Frida I. , Moreno‐Meynard Paulo , Fajardo Alex 
Published: August 2022

Abstract

Nonstructural carbohydrates (NSCs) mediate plant survival when the plant's carbon (C) balance is negative, suggesting that NSCs could predict plant survival under C stress. To examine this possibility, we exposed saplings of six temperate tree species to diverse levels of C stress created by the combination of two light conditions (full light availability and deep shade) and two defoliation levels (severe defoliation and nondefoliation). We then measured survival, biomass and total NSCs and soluble sugars (SSs) concentrations in different organs of both dead and live saplings.

We estimated mean NSCs and SSs contents and concentrations per sapling and fitted logistic generalized mixed‐effects models to determine if NSCs and SSs predict survival. Using inverse prediction modelling, we also determined whether there is a common NSCs and SSs threshold across species at the time of sapling's death.

Defoliation and shade reduced the mean sapling's NSCs and SSs contents, indicating C stress. Mean sapling NSCs and SSs contents and concentrations predicted survival and the robustness of the models improved with the inclusion of species. At death, saplings of the exotic deciduous tree species Acer pseudoplatanus exhibited significantly lower mean NSCs and SSs contents than saplings of the evergreen conifer species Podocarpus nubigenus and lower stem NSCs and SSs concentrations than the broadleaf evergreen species Drimys winteri.

The energetic role that NSCs and SSs play in plants under C stress was evidenced by the capacity of these compounds to predict sapling survival under C stress. No common threshold of NSCs and SSs contents or concentrations for sapling survival amongst species was found, indicating that the level of these compounds may not be good proxies for interspecific comparisons of tolerance to C stress. Presumably, there are species‐specific limits for the mobilization and use of NSCs and SSs in metabolism.

Our results anticipate that the inclusion of NSCs and SSs in modelling will improve predictions regarding tree responses to ongoing climate change. Nonetheless, a better understanding of the many roles that carbohydrates play in plant survival under C stress is required to scale predictions up to the community level.

Read the free Plain Language Summary for this article on the Journal blog.
Impact of simulation training on the management of shoulder dystocia and incidence of permanent brachial plexus birth injury: An observational study
Authors: Kaijomaa Marja , Gissler Mika , Äyräs Outi , Sten Assi , Grahn Petra 
Published: August 2022

AbstractObjectiveTo study the impact of shoulder dystocia (SD) simulation training on the management of SD and the incidence of permanent brachial plexus birth injury (BPBI).DesignRetrospective observational study.SettingHelsinki University Women’s Hospital, Finland.SampleDeliveries with SD.MethodsMulti‐professional, regular and systematic simulation training for obstetric emergencies began in 2015, and SD was one of the main themes. A study was conducted to assess changes in SD management and the incidence of permanent BPBI. The study period was from 2010 to 2019; years 2010–2014 were considered the pre‐training period and years 2015–2019 were considered the post‐training period.Main outcome measuresThe primary outcome measure was the incidence of permanent BPBI after the implementation of systematic simulation training. Changes in the management of SD were also analysed.ResultsDuring the study period, 113 085 vertex deliveries were recorded. The incidence of major SD risk factors (gestational diabetes, induction of labour, vacuum extraction) increased and was significantly higher for each of these factors during the post‐training period (p < 0.001). The incidence of SD also increased significantly (0.01% vs 0.3%, p < 0.001) during the study period, but the number of children with permanent BPBI decreased by 55% after the implementation of systematic simulation training (0.05% vs 0.02%, p < 0.001). The most significant change in the management of SD was the increased incidence of successful delivery of the posterior arm.ConclusionsSystematic simulation‐based training of midwives and doctors can translate into improved individual and team performance and can significantly reduce the incidence of permanent BPBI.
Knowledge structure of emergy theory in the field of eco‐compensation research: A grounded theory approach
Authors: Xu Xiumei , Tan Yilan , Feng Chao 
Published: August 2022

AbstractAlthough emergy theory has made progress in the field of eco‐compensation research, there is still a lack of review articles, summarizing the existing knowledge structure in this area of study. Accordingly, the objective of this paper is to provide a reference for researchers by characterizing the current status of emergy theory in the field of eco‐compensation and to establish the internal logic structure among existing studies, based upon a qualitative analysis of textual data. Inspired by the grounded theory, twelve concepts within five categories of emergy theory were extracted by open, axial, and selective coding of relevant literature. Concepts were extracted from the texts and categories were determined according to the inherent logical relationships among those concepts. The “knowledge structure model of emergy theory in the field of eco‐compensation” was constructed and the following five principal categories were identified: “emergy indicators system,” the “integration of methods and theories,” “research subjects,” “calculation of compensation standards,” and “research concerns.” Moreover, core and supporting genera were also identified from these five axial codes. Finally, the research focuses and hotspots were explored according to the theoretical frameworks as indicated by the core and supporting genera. The findings of this paper provide a reference for researchers to further promote innovation in the application of emergy theory in the field of eco‐compensation.
Analgesic benefits of the quadratus lumborum block in total hip arthroplasty: a systematic review and meta‐analysis
Authors: Hussain N. , Brull R. , Speer J. , Hu L.‐Q. , Sawyer T. , McCartney C. J. L. , Abdallah F. W. 
Published: August 2022

SummaryThe quadratus lumborum block (QLB) is reported to reduce pain and improve function following total hip arthroplasty; however, randomised controlled trials evaluating the benefits of adding this block to general or spinal anaesthesia in this population are conflicting. We performed a systematic review seeking randomised controlled trials investigating QLB benefits for total hip arthroplasty, stratifying comparisons regarding the addition of QLB to either general or spinal anaesthesia. The primary outcome was 24‐h area under the curve (AUC) pain score. Pain scores were interpreted in the context of a population‐specific minimal clinically important difference of 1.86 cm on a 10‐cm visual analogue scale, or an AUC pain score of 5.58 cm.h. Secondary outcomes included analgesic consumption, functional recovery and opioid‐related side‐effects. In all, 18 trials (1318 patients) were included. Adding QLB to general or spinal anaesthesia improved 24‐h AUC rest pain scores by a mean difference (95%CI) of −3.56 cm.h (−6.70 to −0.42; p = 0.034) and − 4.19 cm.h (−7.20 to −1.18; p = 0.014), respectively. These improvements failed to reach the pre‐determined minimal clinically important difference, as did the reduction in analgesic consumption. Quadratus lumborum block improved functional recovery for general, but not spinal, anaesthesia. Opioid‐related side‐effects were reduced with QLB regardless of anaesthetic modality. Low‐to‐moderate quality evidence suggests that the extent to which adding QLB to either general or spinal anaesthesia reduces postoperative pain and opioid consumption after total hip arthroplasty is statistically significant but may be clinically unimportant for most patients. However, adding QLB to general anaesthesia might enhance functional recovery. Taken together, our findings do not support the routine use of QLB as part of multimodal analgesic regimens for total hip arthroplasty.