bluuebunny/crossref_metadata_2025_split huggingface dataset:
Drug review sentimental analysis based on modular lexicon generation and a fusion of bidirectional threshold weighted mapping CNN‐RNN
Authors: Dubey Gaurav , Singh Harivans Pratap , Sheoran Kavita , Dhand Geetika , Malik Pooja 
Published: December 2022

SummaryIn drug review sentimental analysis (SA), users can share their experiences after consuming the drugs, which provides an accurate decision about the safety of the drug and public health. Patient‐written medical and health‐care reviews are among the most valuable and informative textual content on social media, but researchers in the areas of natural language processing (NLP) and data mining have not researched them thoroughly. These reviews provide insight into patients' interactions with doctors, treatment, and satisfaction or dissatisfaction with health services. The existing approaches have some problems like exploding/vanishing gradients and do not have sequential modeling. When learning long reviews, the exploding and vanishing gradient problems occurs. This problem makes it hard to tune parameters and learn in the network. The existing methods do not have sequential modeling because they fail to extract long dependencies for long reviews in both backward and forward directions. To overcome these issues, we proposed a Modular Lexicon Generation and a Fusion of Bidirectional threshold weighted mapping CNN‐RNN (MLBTWCR) for classifying drug reviews based on users opinions. The Aspect based Modular Lexicon generation using the Advanced Dragon Fly Algorithm (AMLDA) is used to generate the score values for the lexicon and labels based on aspect. The Bidirectional Dropout Long and Short‐Term Memory (Bi‐DLSTM) and Bidirectional Gated Recurrent Unit (Bi‐GRU) used for extracting long dependencies and for performing the sequence of arbitrary length in both backward and forward directions. The experimental results are evaluated using
Drugslib.com and
Drugs.com datasets. Based on evaluation result, the proposed MLBTWCR gives accuracy of 93.02%, recall of 88.72%, error rate of 11.2, false positive rate (FPR) of 11.3, false negative rate (FNR) of 13.6, running time of 15 s, and convergence speed of 0.2 and F‐measure of 92.64%. Hence, our method performs well for the drug reviews classification based on aspects.
Women empowerment and entrepreneurial intention: A pathway to achieve sustainable development goal (SDG‐5)
Authors: Bilal Ahmad Raza , Rosato Pierfelice , Campo Raffaele , Leopizzi Rossella 
Published: December 2022

AbstractThis research aims to investigate the impact of social networking, family support, social dominance orientation and, access to finance on the entrepreneurial intention among Omani women and to examine the mediating role of entrepreneurial persistence and entrepreneurial passion between growth constraints and the entrepreneurial intention on Omani women. The contribution of women in the development of the economy has received great attention in the past years. Therefore, to motivate women to engage in entrepreneurship, it is necessary to understand the growth impediments that impact their entrepreneurial intentions to achieve sustainable development goal (SDG‐5). By using the stratified sampling method, this study collected data from 262 Omani women from nine regions, including Al Batinah North, Al Batinah South, AlBuraimi, Muscat, Ash Sharqiyah South, Ad Dakhiliyah, Dhofar, Ad Dhahirah, and Musandam. The study's findings showed that social networking significantly impacts entrepreneurial intention and entrepreneurial persistence. At the same time, access to finance and family support has an insignificant effect on entrepreneurial persistence, entrepreneurial passion, and entrepreneurial intention. The findings indicate the role of the mediating variables between growth constraints and entrepreneurial intention. Based on findings that offer valuable insight, several recommended strategies are provided for policymakers in general and for the socio‐economic development of Omani women, in particular.
What affects the quality of sustainability report texts? Evidence from China
Authors: Zhang Zhengxin , Xu Bing , Li Piao 
Published: December 2022

AbstractWe relied on web crawlers and text analysis techniques to develop a new method for measuring the quality of sustainability report texts, and accordingly discussed the impact of chief executive officers' (CEOs') characteristics on the quality of sustainability report texts. We found that companies led by younger CEOs and CEOs with better‐educated, financial and overseas backgrounds provided higher quality sustainability reports, while companies led by female CEOs and CEOs with academic backgrounds provided poorer quality sustainability reports. We also unpacked the “black box” of sustainability report quality, grouping it into three aspects: comprehensiveness, objectivity and reliability. Further research found that CEO characteristics had a greater impact on the quality of sustainability reports in the sample of voluntary and non‐state‐owned enterprises. Our study has the potential to contribute to the selection of CEOs and the improvement of sustainability disclosure.
Sulfur‐Doped rGO Aerogel Enables the Anchoring of 1T/2H MoS2 for Durable Oxygen Reduction Reaction Catalyst Support
Authors: Sun Lian , Wang Honglei , Yan Xingheng , Li Wudi , Xie Haijiao , Yang Yaping , Yu Jinshan , Zhou Xingui 
Published: December 2022

AbstractDurability is crucial for the long‐term application of cathode oxygen reduction reaction (ORR) catalysts in fuel cells. In this work, sulfur was successfully doped into reduced graphene oxide (rGO) aerogels to achieve the formation of 1T/2H hybrid phase MoS2, obtaining MoS2@S‐rGO‐300 composite ORR catalyst support. After loading ultrafine Pt nanoparticles, Pt/MoS2@S‐rGO‐300 showed not only an enhanced ORR activity, but also a significantly improved stability after 10000 cycles. The mass activity retention for Pt/MoS2@S‐rGO‐300 after cycles reached 89.94 %, while that of Pt/rGO was only 37.44 %. Density functional theory calculations revealed that the enlarged binding energy between Pt atoms and MoS2@S‐rGO‐300 led to the prevention of Pt agglomeration as well as Ostwald ripening.
Migratory birds with delayed spring departure migrate faster but pay the costs
Authors: Dossman Bryant C. , Rodewald Amanda D. , Studds Colin E. , Marra Peter P. 
Published: December 2022

AbstractMigratory birds that experience poor overwintering conditions are often late to arrive at the breeding grounds, which is known to depress individual fitness. Despite the importance of this carryover effect, few studies have investigated how individuals can modify migratory behaviors en route to reduce delays on arrival and whether accelerating migration incurs survival costs. To examine this, we used Motus Wildlife Tracking System to track individual American redstarts (Setophaga ruticilla) as they migrated from wintering grounds in Southwest Jamaica through Florida en route to their breeding areas. We leveraged long‐term data on spring departure timing and breeding latitude to quantify the relative departure dates (early vs. delayed) of tagged individuals, which we then related to individual migration rates and apparent annual survival. Compared to those initiating migration earlier, individuals that departed relatively late (10‐day delay) migrated at a 43% faster rate, which decreased their annual survival by 6.3%. Our results are consistent with the hypothesis that spring migrants use speed to compensate for departure delays despite incurring survival costs. This compensatory behavior may potentially underly differential survival during spring migration and may be particularly widespread across short‐lived migratory birds generally considered time‐constrained.
BaO‐Catalyzed α‐Deuteration of Ketones, Sulfones, Sulfoxides, and Nitriles
Authors: Fan Hui‐ke , Yang Sen , Li Jun‐hua , Teng Qiao‐qiao , Chen Ming 
Published: December 2022

AbstractHerein a facile methodology of α‐deuterating ketones, sulfoxides, sulfones and nitriles using catalytic BaO was developed. The protocol allowed high d‐incorporation in a single‐run with broad functional group tolerance and was scalable and applicable in preparing exemplary bioactive ketone candidates.
Stereoselective Synthesis of Enamides through Palladium‐Catalyzed Oxidative Amidation of Conjugated Olefins with 2‐Pyridones
Authors: Zhao Shuai , Lu Bin‐Wei , Bao Ning , Yin Zi‐Jian , Qian Mingcheng , Cao Lin , Geng Min , Lin Ye , Chen Xin 
Published: December 2022

AbstractA palladium‐catalyzed oxidative amidation of conjugated olefin with 2‐pyridone is described. A series of E‐Enamides were synthesized in a highly stereocontrolled manner. The reaction also accommodates other cyclic and acyclic amides. Z‐Enamides were predominantly prepared for primary amides probably due to the presence of an intramolecular hydrogen bond. Gram‐scale synthesis of enamide and the following oxidative annulation with diphenylacetylene demonstrates the synthetic utility of this reaction.
Amperometric sandwich‐type aptasensor based on peroxidase mimetic Au@Pt for the carcinoembryonic antigen
Authors: Li Hui , Zhang Yuting , Chang Anqi , Cai Shixin , Zhou Nandi 
Published: December 2022

AbstractFor sensitive analysis of cancer biomarker carcinoembryonic antigen (CEA), an amperometric sandwich‐type aptasensor is proposed based on a signal amplification strategy of Au@Pt bimetallic nanoprobes. As the excellent catalytic activity to hydrogen peroxide (H2O2), core‐shell Au@Pt nanoparticles are employed as nanoprobes by conjugating directly with the secondary aptamer of CEA (Apt‐II). Due to the synergic recognition effect of dual aptamers and the excellent catalytic activity of nanoprobes, this amperometric sandwich‐type aptasensor for CEA exhibits high specificity and good sensitivity with a limit of detection of 0.31 ng/mL, along with a wide linear range from 0.1 ng/mL to 100 ng/mL.
Doping engineering of scandium‐based solid‐state electrolytes toward superior ionic conductivity
Authors: Zhang Hongtu , Zeng Zhichao , Shi Xiaomeng , Wang Chun‐Hai , Du Yaping 
Published: December 2022

AbstractOne key research point of solid‐state electrolytes (SSEs) is ionic conductivity. To date, their ionic conductivity is relatively low to meet the requirements of practical applications; thus, more investigations on the migration mechanisms are needed. Here, we constructed scandium‐based halide SSEs (Li3‐xSc1‐x(Zr/Hf)xCl6, x = 0 ~ 0.5). The highest ionic conductivities (1.61 and 1.33 mS/cm) and the lowest activation energies (0.326 and 0.323 eV) are shown in Li2.6Sc0.6Zr0.4Cl6 (LSZC~0.4) and Li2.6Sc0.6Hf0.4Cl6 (LSHC~0.4), respectively. Their electrochemical windows in the cells of Li/Li7P3S11/LSZC~0.4/LSZC~0.4‐C and Li/Li7P3S11/LSHC~0.4/LSHC~0.4‐C are 1.3 ~ 4.2 V and 1.6 ~ 4.1 V versus Li+/Li, respectively. The crystal structures and the Li+ chemical environments were investigated by X‐ray diffraction and 7Li solid‐state magic angle spinning nuclear magnetic resonance, indicating weaker bond strengths of LiCl to facilitate the transportation of Li+. The potential reason explaining the increased ionic conductivity was determined based on the bond valence site energy theory.image
Improved geospatial analysis of shoreline modification using a weighted‐average‐based novel formulation
Authors: Mohanty Asmita , Rajani Mandyam B. , Majumdar Rudrodip , Nayak Shailesh 
Published: December 2022

AbstractThis study presents a novel weighted‐average method (WAM) that captures the detailed nuances of shoreline change patterns over long and short periods by considering shorelines belonging to five different time frames. Using the WAM, the average shoreline modification for the longer period (136 years with intervals of ~34 years) and for the shorter period (annual changes over a period of 5 years) have been calculated for the 9 km stretch of the Kollam coast in Kerala, India. Historically, Kollam has been a prominent seaport on the Malabar Coast of India and was extensively mapped due to its importance for political, strategic, and trade reasons. The coastal information available in these older maps is unique as there are no comparable data for the coastline of that period that can be used to assess changes along the coast. The WAM demonstrated the efficacy of the historical maps as pivotal reference points. It reliably captured the different shoreline activities (i.e., growing, stable, and receding regions) of natural and anthropogenic origins within the study area, and the findings are consistent with results obtained by using the linear regression rate (LRR) and the end point rate (EPR) methods. This work presents both qualitative and quantitative analyses to evaluate shoreline change using various statistical and mathematical methods. The findings should serve as baseline information for coastal management, notably mitigating coastal hazards—whether of natural or anthropogenic origin—which could result in the enhancement of ecosystem services for coastal communities.
Structural and geochemical studies of the Palaeozoic granites from Dalhousie region of Himachal Himalaya: Implications on petrogenesis and deformation of strongly peraluminous S‐type granites
Authors: Tripathi Kavita , Choudhary Shubham , Joshi Mayank , Sharma Rajesh 
Published: December 2022

The Palaeozoic granites forming the Dalhousie pluton occur as an elongated body intruded into the core of an antiform in Salkhala metasedimentary rocks and are referred to herein as Dalhousie granites (DG). The studied mesoscopic structures, for example, well‐developed and randomly distributed megacrysts of K‐feldspar at the core part of massif, show undeformed porphyritic nature, whereas augen along with the mylonitic foliation and parallelly aligned feldspar megacrysts are dipping towards north‐north‐east (NNE) in the marginal part. The presence of aplite veins is evidence of final stage crystallization, where these rocks rapidly crystallized from siliceous residual fluids/solutions that escaped along fractures in the granites. Moreover, the granites show intrusive as well as thrusted contact with the Chamba metamorphics. The microscopic study from the marginal parts shows the dynamic recrystallization of quartz along with the fractures filled with secondary material oriented opposite to the top‐to‐the‐SW. Whereas euhedral quartz grains with undeformed grain boundaries, compositional zoning in plagioclase, and magmatic (perthite) texture of K‐feldspar are present in the core of Dalhousie pluton. In addition, a new whole‐rock geochemical dataset of DG is presented and investigated to elucidate the petrogenesis and tectonic environment. The geochemical data shows that DG (dominantly monzogranites) are formed from a pelitic source‐derived, (molar Al2O3/CaO + Na2O + K2O > 1.1) strongly peraluminous (S‐type) calc‐alkaline magma. This magma was generated by muscovite vapour absent dehydration melting. Harker bivariate plots indicate that fractional crystallization was a dominant process during the evolution of these granites. The tectonic discrimination diagrams suggest that DG were generated in syn‐collisional setting. Exceptionally high Pb in DG occurred due to primary melt generation at low‐temperature during partial melting (low‐degree melting) of the pelitic source rock. Trace and rare earth elements characteristics, such as positive anomaly of Zr show a notable amount of zircon as one of the accumulating phases. A pronounced negative Eu anomaly (EuN/Eu* = 0.04–0.66), along with high silica content and highly varied trace element ratios in these rocks, show that these are fairly evolved granites.
Persistent depressive symptoms are associated with frontal regional atrophy in patients with Alzheimer's disease
Authors: Sinclair Lindsey Isla , Ballard Clive G. ,   for the Alzheimer's Disease Neuroimaging Initiative
Published: December 2022

AbstractBackgroundDepression in individuals with Alzheimer's disease (AD) is common, difficult to treat and inadequately understood. Previous studies have identified possible differences in regional brain atrophy in individuals with AD and depression, but the results have been inconsistent and some studies had less robust definitions of depression. We aimed to examine regional brain atrophy in two large dementia focused cohorts.MethodsWe used data from Alzheimer's disease neuroimaging initiative (ADNI) and the National Alzheimer's Co‐ordinating Center (NACC), for those with data from at least one MRI scan. Depression ratings were available using the Geriatric Depression Scale (GDS) and Neuropsychiatric Inventory (NPI). Intermittent depressive symptoms were defined as one episode above threshold (≥8 on GDS, ≥6 on NPI depression subscale and ≥2 on the Neuropsychiatric Inventory version Q depression sub‐scale) and persistent as ≥2 episodes. Derived regional volumetric data was available from ADNI and the NACC.ResultsData was available from 698 individuals with AD in NACC and from 666 individuals in ADNI. We found no evidence of between group differences in regional brain volume at baseline, or of differential atrophy in NACC. In ADNI we found evidence of increased brain atrophy in several frontal brain areas.LimitationsBecause this study was limited to those with MRI data, the numbers in some analyses were low. MRI parcellation differed between studies making direct comparison difficult. For some individuals only the NPI was used to rate depression.ConclusionsWe have found mixed evidence of increased regional atrophy in depression in AD, mainly in frontal brain regions. We found no evidence to support a vascular basis for depression in AD.
Communication quality and relational self‐expansion: The path to leadership coaching effectiveness
Authors: Passarelli Angela M. , Trinh Mai P. , Van Oosten Ellen B. , Varley Amanda 
Published: December 2022

AbstractLeadership coaching—a relational process by which a professional coach works with a leader to support their development—is a common component of learning and development portfolios in organizations. Despite broad agreement about the importance of the coaching relationship, relational processes remain undertheorized, failing to account for the growth and intertwining of coach‐leader self‐concepts as they engage in a generative and co‐creative coaching process. To address these shortcomings, we reconceptualize the relational process within coaching as one of relational self‐expansion and theorize that the communication channel and communication quality impact relational self‐expansion which, in turn, influences coaching effectiveness. Our hypotheses are tested in a field experiment featuring random assignment to experimental conditions (communication channels) in which a coaching intervention was deployed in five organizations. Using structural equation modeling, we demonstrated that communication quality and relational self‐expansion during the coaching process positively predicted coaching effectiveness. Contrary to expectations, communication quality did not differ by channel (phone, videoconference, face‐to‐face) nor did it predict relational self‐expansion.
A Geneticist Transcribing the Chemical Language of Bacteria
Authors: Miller Conrad Laura C. , Perez Lark J. 
Published: December 2022

AbstractThe study of quorum sensing, bacterial cell‐to‐cell communication mediated by the production and detection of small molecule signals, has skyrocketed since its discovery in the last third of the 20th century. Building from early investigations of bacterial bioluminescence, the process has been characterized to control a numerous and growing number of group behaviors, including virulence and biofilm formation. Bonnie Bassler has made key contributions to the understanding of quorum sensing, leading interdisciplinary efforts to characterize key signaling pathway components and their respective signaling molecules across a range of gram‐negative bacteria. This review highlights her work in the field, with a particular emphasis on the chemical contributions of her work.
Self‐managed abortion: Aligning law and policy with medical evidence
Authors: Skuster Patty , Moseson Heidi , Perritt Jamila 
Published: December 2022

AbstractPeople have always and will always find ways to try to end their pregnancies when necessary. Many do so safely without the involvement or direct supervision of healthcare professionals by self‐managing their abortions. In 2022, the well‐established safety and efficacy of abortion medications prompted WHO to fully endorse self‐managed medication abortion as part of a comprehensive range of safe, effective options for abortion care. But despite robust evidence supporting the safety and effectiveness of the self‐use of medications for abortion, abortion laws and policies around the world remain at odds with clinical evidence and with the realities of self‐managed medication abortion in the present day. The present article considers legal issues related to self‐managed abortion and addresses the role of obstetricians, gynecologists, and other healthcare professionals in promoting clinical and legal safety in abortion care through support of self‐managed abortion.
Metabolic inhibitor screening identifies dihydrofolate reductase as an inducer of the tumor immune escape mediator CD24
Authors: Boese Austin C. , Hwang Jung Seok , Young Isabelle , Malin Courteney M. , Avalos Vanessa , Kang JiHoon , Kang Sumin 
Published: December 2022

AbstractImmune checkpoint inhibitors (ICIs) have improved the clinical management of some cancer cases, yet patients still fail to respond to immunotherapy. Dysregulated metabolism is a common feature of many cancers, and metabolites are known to modulate functions in cancer cells. To identify potential metabolic pathways involved in anti‐tumor immune response, we employed a metabolic inhibitor‐based drug screen in human lung cancer cell lines and examined expression changes in a panel of immune regulator genes. Notably, pharmacologic inhibition of dihydrofolate reductase (DHFR) downregulated cancer cell expression of cluster of differentiation 24 (CD24), an anti‐phagocytic surface protein. Genetic modulation of DHFR resulted in decreased CD24 expression, whereas tetrahydrofolate, the product of DHFR, enhanced CD24 expression. DHFR inhibition and the consequent CD24 decrease enhanced T cell‐mediated tumor cell killing, whereas replenishment of DHFR or CD24 partially mitigated the immune‐mediated tumor cell killing that resulted from methotrexate treatment in cancer cells. Moreover, publicly available clinical data analyses further revealed the link between DHFR, CD24, and the antitumor immune response in lung cancer patients. Our study highlights a novel connection between folate metabolism and the anti‐tumor immune response and partially interprets how DHFR inhibitors lead to clinical benefits when combined with cancer immunotherapy agents.