bluuebunny/crossref_metadata_2025_split huggingface dataset:
COVID-19 and sensorineural deafness: systemic review
Authors: Hussain Tanvir , Ghaznain Amna , Patil Nash 
Published: September 2022

Coronavirus is a pandemic that hits the world when least expected, causing health chaos. A plethora of evidence from recent studies indicates that the novel coronavirus (COVID-19) disease has led to various health problems. For instance, a range of neurological symptoms may worsen in the event of a Coronavirus infection. The virus is linked to sudden sensorineural deafness also (used in this article) known as (SSNHL) sudden sensorineural hearing loss. Studies indicate that due to the vulnerability of the inner ear to viruses, SSNHL is believed to develop after severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) exposure, frequently leading to prolonged morbidity and deterioration of quality of life. This is because otologic symptoms relating to SSNL outlined in patients with coronavirus infection. However, no definitive link has been found between COVID-19 and SSNHL. This systematic assessment investigated the relationship between the prevalence of SSNHL and COVID-19 disease. Additionally, the review utilizes patients having coronavirus-related sudden sensorineural hearing loss from the ENT outpatient department; all the patients in this review are at least 18 years of age. Sensorineural deafness generally appeared within a couple of days and two months following the COVID-19 diagnosis, while some individuals experienced it prior to the detection of COVID-19. As previously stated, the purpose of this article is to conduct a systematic literature review to assess the potential link between COVID-19 infection and SSNHL. SARS-CoV-2 might impair cochlear function, according to existing evidence; however, the evidence is scarce. To assess the long-term impact of this virus on the inner ear, substantial cohort and potential investigations are required.
Cholesteatoma of the middle ear: about 50 cases in Donka University Hospital
Authors: Keita Abdoulaye , Diallo Ibrahima , Diallo Mamadou A. , Diallo Mamadou M. R. , Fofana Mamady , Barry Kadiatou , Bayo Abdoulaye 
Published: September 2022

<p class="abstract"><strong>Background:</strong> Cholesteatoma of the middle ear remains a dangerous chronic otitis that can potentially lead to serious complications. The treatment remains exclusively surgical. The aim of the study was to describe the epidemiology and anatomical functional results of surgery for middle ear cholesteatoma.</p><p class="abstract"><strong>Methods:</strong> This was a cross-sectional study of retrospective data collection over 5 years (from 01 January 2016 to 30 December 2020) and conducted at the ENT and head and neck surgery department of Donka University Hospital. </p><p class="abstract"><strong>Results:</strong> We collected 50 cases of cholesteatoma. The prevalence was 1.33%. The mean age was 33.58±18.07 years. The sex ratio was 0.92. Purulent otorrhea (96%) and hearing loss (84%) were the main symptoms. We noted 56% pocket retraction and 36% tympanic perforation. Conductive hearing loss accounted for 76% of cases. The CT scan of the rocks noted 69.89% of filling associated with the lysis of the walls of the middle ear. Masto-atticotomy associated with tympanoplasty was performed in 78.89% of cases. Encapsulated cholesteatoma was the most frequent (66%). The epitympanum was its elective seat (44%). The ossicular chain was lysed in 76%. The incus was the most affected ossicle (66%). Ossiculoplasty was performed in 66%. The postoperative course was simple (74%). Medium and long-term follow-up revealed normal anatomical restoration of the neo-tympanum in 94%. Hearing improvement was noted in all our patients with an average hearing gain of 10-30 dB in 52%.</p><p class="abstract"><strong>Conclusions:</strong> The treatment was exclusively surgical. However, we obtained largely satisfactory anatomical and functional results.</p>
Juvenile fibroadenoma of the breast
Authors: Jagtap Sunil Vitthalrao , Jagtap Swati Sunil , Goswami Nidhi Rajubhai , Desai Neha Babasaheb 
Published: September 2022

Juvenile fibroadenoma is a rare variant of fibroadenoma and is characterized by rapidly enlarging, painless, and unilateral masses. We presents a case of juvenile fibroadenoma of the breast in a 14 year old girl, presented with rapidly growing mass in the right breast of four months duration. On local examination a solitary, firm, mobile, unilateral, non-tender mass was felt in the upper and lower outer quadrant of the right breast, measuring 6.5 x 4.1 x 3.5cm. The overlying skin was normal. There was no axillary lymphadenopathy. The sonomammography of the right breast showed a single, oval, hypoechoic, well circumscribed mass lesion with cleft like spaces features suggestive of complex fibroadenoma BIRADS IV a. On fine niddle aspiration cytology showed sheets of hyperplastic benign ductal epithelial cells with myoepithelial cells and a background of benign bipolar nuclei and blood, without inflammatory cells. It was suggestive of fibroadenoma. She underwent right lumpectomy with breast conservation. We received right breast lumpectomy specimen. On gross showed a well-circumscribed, grey white, firm mass m 6.3 x 4.1 x 3.2 cm. On histologic features reported as juvenile fibroadenoma right breast. The postoperative period was uneventful and she recovered well and advise regular follow up. Juvenile fibroadenomas are rare benign breast tumors that should be distinguished from other masses of breast. Herewith we are presenting case of Juvenile fibroadenoma for its clinical, radio imaging, pathological features and management.
Riesgo de la prescripción de opioides para el manejo del dolor
Authors: Fajardo Zapata Alvaro Luis , Caicedo Murte Nidia Patricia 
Published: September 2022

Actualmente existe una intensa prescripción de opioides para el manejo de todo tipo de dolor a nivel clínico, razón por la cual es importante considerar los posibles daños derivados de esta actividad, tales como tolerancia, adicción, dependencia y sobredosis. La medicación de opiáceos o sus derivados de manera irracional para el manejo del dolor agudo o crónico puede ser la puerta de entrada a las drogodependencias. Muchos adictos a opiáceos informaron haber estado expuestos por primera vez a los opioides a través de una prescripción médica para el tratamiento del dolor. Por ello, es importante evaluar por parte de los profesionales de la salud el uso a largo plazo de estos medicamentos para el manejo del dolor, porque estudios han evidenciado una relación entre el uso clínico y la dependencia de estos, sobre todo en adolescentes y adultos jóvenes sin experiencia en opiáceos que fueron sometidos a procedimientos quirúrgicos y dentales.
INTERPRETING ALGORITHM FOR A TEXT COGNITIVE SCRIPT ARCHITECTONICS IN NON-FICTION
Authors: Ogneva Elena A. 
Published: September 2022

Aim. To create an interpretive taxonomic model of a text cognitive script, represented in the conceptual domain of documentary prose.Methodology. By means of the innovative author’s interpreting algorithm for text cognitive script architectonics represented in the conceptual domain of documentary prose, the specific features of a complex taxonomic model as a dynamic textual research construct are identified.Results. For the first time, a complex taxonomic model of a text cognitive script, represented in the conceptual domain of documentary prose, has been interpreted; the author’s interpreting algorithm for text cognitive script architectonics as a dynamic construct of the conceptual domain of documentary prose is proposed; a typology of research constructs which compose the conceptual domain of documentary prose is proposed; the correlation between the text cognitive script architectonics and the functioning of text cognitive attractors in the conceptual domain of documentary prose is substantiated.Research implications. The results of this scientific research contribute to the further development of cognitive poetics, the methodology of interpretative taxonomic modeling of textual cognitive constructs. The terms “documentary and literary concept” and “spatial-temporal cyclicity” are introduced into the scientific thesaurus. The author’s typology of documentary and literary concept is presented. The results of the study can be applied in lectures on text theory and cognitive poetics.
QUALITATIVE SINGULARITY OF VERBAL AGGRESSION IN THE CONTEXT OF VARIOUS GENERAL PROFESSIONAL DEFORMATIONS OF EDUCATORS
Authors: Simatova Oksana B. 
Published: September 2022

Aim. To investigate the frequency and content structure of verbal aggression among educators with various professional deformities.Methodology. The study of verbal aggression was carried out using visual observation with verbal registration of speech material.Results. The empirical study revealed statistically significant differences in the frequency of occurrence and the content structure of verbal aggression in various professional deformations of educators.Research implications. The study contributes to the understanding of verbal aggression as a significant component of a number of professional deformations of a teacher. The results of the study determine the effective direction of preventive and correctional work in relation to professional deformities of teachers, taking into account the frequency and qualitative originality of verbal aggression manifestations.
The Effect of Ulnar Styloid Fractures on Patient-Reported Outcomes After Surgically Treated Distal Radial Fractures
Authors: Clementsen Ståle Ørstavik , Jakobsen Rune Bruhn , Hammer Ola-Lars , Randsborg Per-Henrik 
Published: September 2022

Background:
Ulnar styloid fractures (USFs) are often associated with distal radial fractures (DRFs). When unstable DRFs are treated surgically, any associated USF is most commonly left untreated. The purpose of this study was to evaluate the effect of a concomitant USF on outcome after surgical stabilization of a DRF.

Methods:
Data from 2 randomized controlled trials on the treatment of unstable DRFs were pooled. The effect of a USF on the QuickDASH, EQ-5D, pain, and range of motion at 2 years was evaluated.

Results:
Two hundred and eighty-one patients were included; 177 (63%) had an associated, untreated USF. An unadjusted analysis demonstrated no significant difference in functional or patient-reported outcome measures (PROMs) at 2 years between patients with or without a concomitant USF. When controlling for confounding factors, the presence of a USF did not predict change in any of the PROMs from baseline to 2 years. A concomitant USF also did not predict change in grip strength or range of motion, except for a small effect on extension (−4.1°; 95% confidence interval, −7.5° to −0.8°; p = 0.02), which probably does not have clinical relevance.

Conclusions:
A USF in combination with a DRF does not affect PROMs, range of motion, or grip strength. We recommend that concomitant USFs be left untreated when treating a DRF with surgical fixation.

Level of Evidence:
Prognostic Level I. See Instructions for Authors for a complete description of levels of evidence.
A planted forest in the mountain steppe of Tabriz, Iran. Visitor’s perceptions of Eynali Urban Woodland Park
Authors: Sabouri Ramin , Breuste Jürgen , Rahimi Akbar 
Published: September 2022

Abstract

Eynali Urban Woodland Park (EWP) is a large mountain park in Tabriz, Iran, and is the largest urban woodland park in Iran. It was developed to increase the urban green space in the growing city of Tabriz for recreation, climate improvement, biodiversity, and ecological connection between the city and its natural surroundings. The planted hilly woodland is located in a natural mountain steppe in a semi-arid region andneeds intensive management, including irrigation.
By questioning of 277 randomly selected park visitor's frequency of visits, activities, accessibility, preferences, and especially nature preferences were analyzed using visualization of different nature types by photographs. The management targets were compared to visitors’ perceptions, preferences, and acceptances.
The results show, visitors prefer a natural surrounding instead of artificial landscape design. Expectations of visitors for specific natural design attractions are lower than the actual status offers, higher for social security, quality of infrastructure, accessibility, and utilization. Especially important are security by monitoring and guarding, enhancing picnic sites, improving the lighting system for evening visits, continuing forestry, public transport, and providing natural risk protection.
Most visitors prefer nature-near vegetation, dry grassland with shrubs partly planted with trees and bushes, followed by planted forest. The planted forest is not the prefered preference. Vistors’ mental nature imagination matches quite well with the nature experience they have from the surrounding mountain steppe with forest patches.
Conclusions: The use of the visitors’ expectations can improve the park landscape management can reduce the management costs.
Study on the learning curve during the transition from direct lateral to direct anterior approach in total hip arthroplasty : a consecutive one hundred and twenty-seven case series
Authors: Chu Miao , Wang Yong , Jiang Tao , Bao Weiguo , Zhou Jiangang 
Published: September 2022

Abstract
Background: Direct anterior approach (DAA) for primary hip arthroplasty has received increasing attention recently. However, there have been no reports focused on the learning curve when transitioning from direct lateral approach(DLA) to DAA. This study evaluates a single surgeon’s learning curve by examining Procedure Time (PT), Operation Preparation Time (OPT), Operating Room Time(ORT) and other data.
Methods: From 2019 to 2021, a single surgeon’s first 100 cases with DAA and 27 cases with DLA between the learning cure were reviewed. PT, OPT, ORT and other data were analyzed.
Results: Compared with DLA, PT, OPT and ORT had a sharp rise in the first 10 cases. There was no statistical significance in PT after 20 cases, ORT after 30 cases, and OPT after 50 cases. The difference of PT and ORT between group 1(DLA) and group 2(DAA, 1-51 cases), group 2 and group 3(DAA, 51-100 cases) were statistically significant. OPT of Group 1 was the shortest, increased significantly in group 2, gradually decreased in group 3. There were significant differences in blood lossbetween group 1 and group 3, between group 2 and group 3. 4 complications in total, 1 case in group 1, 3 cases in group 2. There were no significant differences in blood transfusion, length of stay and complication rate.
Conclusions: When transitioning from DLA to DAA, an experienced surgeon may be low efficient, with longer PT, OPT and ORT. Great changes appeared after DAA 50 cases, complications and blood loss could be controlled within the safe range.
Enhancing women’s participation in SMEs is a major boost for Zimbabwe’s economic recovery strategy
Authors: Musabayana Godfrey Tambudzayi , Mutambara Emmanuel , Ngwenya Tony 
Published: September 2022

Abstract
The greater involvement of women in the SME sector would improve the economy of the country through a higher participation of the mostly excluded group. The low involvement of women in the SME sector in Zimbabwe is a major cause of concern since they are being marginally involved in the business activities by the current economic environment. This study established that the women are not supported by the government, they lack resources and are incapacitated yet the SMEs are currently the main source of employment for the Zimbabweans. The qualitative research method was used in the study which employed interviews as the main data collection method. The findings of the study will assist the government to promote the participation of women in the SME sector and this will improve the economy of the country. The researcher proposed the strategy that the Zimbabwean government could adopt in order to improve the participation of women in the economic development of the country.
Fostering Small and Medium-sized Enterprises through Public Procurement in Canada: A Data Analytics Approach
Authors: Wu ShiKui , Zhang Kem Z.K. , Farrokhi Kiana 
Published: September 2022

Abstract
Public procurement has been considered as a policy tool to foster small and medium-sized enterprises (SMEs), while the effectiveness remains unclear. This study aims to assess the participation and performance of SMEs in Canadian public procurements. We adopt a data analytics approach in assessing the tenders’ data from the Government of Canada over a ten-year period (2009–2019). We analyzed key factors, identified patterns and profiles in winning contracts, compared the performance between SMEs and large enterprises (LEs), and developed prediction models for contract value. Contract value is found to vary across firm sizes, levels of competitiveness, and supplier’s locations and industries. SMEs are top performers and are strongly complementing LEs with diverse and specialized offerings. A majority of public contracts with SMEs are awarded with relatively small value, short terms and limited to certain service contracts. The random forest regression model is shown to be the best in predicting contract value. The findings provide insights for both governments and SMEs in using procurement more effectively as a policy tool. Future work may validate this research in other countries with traditional method and primary data.
Silibinin inhibits the invasion of human fibrosarcoma cells through MMPs, p-p38 and IL-1β
Authors: In Ah , Kim Moon-Moo 
Published: September 2022

Abstract
Silibinin, from milk thistle (Cirsium japonicum) has been known to suppress lung cancer and liver protection. Due to the defection of normal cells to regulate cell division, cancer cells metastasize into other tissues. Therefore, the development of natural substances to suppress metastasis through MMPs, the metastatic enzymes, is necessary. The purpose of this study is to investigate the effect of silibinin on the metastasis of human fibrosarcoma cells. Cytotoxicity was shown in the presence of silibinin above 20 μM. Silibinin above 20 μM remarkably inhibited the levels of both MMP-2 and MMP-9 activations under PMA treatment condition. Furthermore, silibinin at 25 μM suppressed metastasis by reducing the expression levels of TIMP-1, MMP-2, IL-1β, ERK1/2, and p-p38. Moreover, silibinin above 10 μM inhibited the invasion of HT1080 cells. These results suggest that silibinin could exert an excellent effect on the suppression of metastatic enzymes, leading to the inhibition of cell invasion.
Case Serie of Hybrid Brachytherapy followed by Intensity Modulated Radiation Therapy (HyBIRT) Technique for the Definitive Management of Tongue Squamous Cell Carcinoma (TSCC)
Authors: Musa Muhamad Yusri , Appalanaido Gokula Kumar , Ch’ng Ewe Seng , Shukor Syadwa Abdul , Soon Eu Chong , Noor Siti Noor Fazliah Mohd , Azahari Ahmad Naqiuddin , Kamaruddin Siti Hajariah , Ishak Nor Hafizah , Aziz Mohd Zahri Abdul , Jalil Jasmin 
Published: September 2022

Abstract
Introduction
The Hybrid Brachytherapy followed by Intensity Modulated Radiation Therapy (HyBIRT) technique reverses the commonly used sequence by delivering high dose rate interstitial brachytherapy (HDRIBT) first followed by IMRT in the management of tongue squamous cell carcinomas (TSCC).
Materials and methods
Eleven patients treated with 20Gy in 5 fractions HDRIBT to TSCC followed by definitive IMRT to 69.96Gy to the involved nodes; 61.71Gy to the high risk volume and 56.1Gy to the low risk volume over 33 fractions in a single institution were analyzed retrospectively.
Results
All 11 patients achieved clinical complete response (cCR) and 9 patients with available radiological imaging achieved radiological complete response (rCR) at the primary site. One year locoregional progression-free survival was 90% (95% CI: 73.2% − 100%) and 18-month disease-free survival (DFS) for 8 patients who achieved rCR was 66.7% (95% CI: 30% − 100%). Median times to cCR and rCR at the primary site were 3.91 months and 4.34 months, respectively. Seven out of 8 patients with nodal disease achieved rCR of the nodes with a median time for rCR of 4.58 months. Two patients had persistent ulcer at 8 months and 11 months of follow-up.
Discussion
HyBIRT technique has the advantage of easy tumor identification during HDRIBT applicator insertion, ability to maneuver the subsequent IMRT plan and reduced the overall treatment time (OTT) while delivering tumoricidal dose to gross disease. Studies with larger sample size are needed to further confirm the efficacy of this organ sparring technique.
Determinants of Passenger Brand Preference Decision (a case of long-distance public transport service in Bahir Dar city station, Ethiopia).
Authors: Yimer Ahmed Mohammed , Dessie Tsadiku Setegne , Ali Mohammed Yimam 
Published: September 2022

Abstract

The study was aims to examine the determinants of passenger brand preference decision in a case of long-distance public transport service in Bahir Dar City station. Specifically, the study sought to address the influence of price, availability of a facility, brand name awareness, brand attributes (comfort, customer care, and safety measures), perceived service quality, and employee service on passengers' brand preference decisions. The study used a positivism research paradigm with a deductive research approach and an explanatory research design to investigate the significance level and the direction of its determinant. In this study, a convenience sampling method was employed to select the sample respondents. The collected data through questionnaire was analysed by the ordinal logistic regression model. In accordance, the finding of this study showed that except the availability of facility, all other predictor variables (price, brand name awareness, brand attributes (comfort, customer care/ safety measures), perceived service quality and employee service) have a strong positive effect on passengers’ brand preference decision. To survive the present competitive pressure and to take the bus as the preferred brand in the industry, the Road transport firms should be required to manage and give more attention to the price charged, increase the level of awareness, creation of comfort, customer care, and safety measures, provide a better quality of service, and improve employees’ hospitality of service