bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perfil lipídico em pessoas iniciando a terapia antirretroviral com regimes baseados em efavirenz ou dolutegravir em um centro de referência no Brasil: um estudo de coorte
Authors: Fernandes Ana Cristina da Silva , Cesar Jorgino Júlio , Bonolo Palmira de Fátima , Souza Clessius Ribeiro de , Ceccato Maria das Graças Braga 
Published: April 2022

Objetivo: Comparar o impacto no perfil lipídico (PL) em pessoas iniciando a terapia antirretroviral (TARV) baseados pré e pós uso de efavirenz (EFZ) ou dolutegravir (DTG). Métodos: Coorte prospectiva onde foi estratificados dois grupos, as pessoas vivendo com HIV (PVIV) que iniciaram esquema com DTG ou EFV. A dislipidemia foi definida por critérios laboratoriais no período entre setembro de 2015 a outubro de 2017. Utilizados testes paramétrico e não paramétrico e testes de pares combinados, considerando o p <0,05 estatisticamente significativo. Resultados: estudados 468 indivíduos estratificados em dois grupos, com (n=180) ou sem (n=288) registros dos exames laboratoriais no tempo T0 (início do tratamento) ou no T48 (12 meses após a dispensação dos antirretrovirais. Entre esses 180, 60 (33,1%) estavam em uso de DTG e 113 (62,4%) em uso de EFZ. Nas comparações do nível sérico (mg/dl) do PL, pré e pós TARV, todos os valores apresentaram aumento e estaticamente significativo para o HDL (p<0,001). Foi analisado a variação do PL, pós TARV e em relação ao uso de EFV e DTG. Em relação ao EFZ, houve aumento do nível sérico de todo o PL, estaticamente significativo para o HDL. Em relação ao DTG, houve aumento do nível sérico apenas para o VLDL que não foi estaticamente significativo. Conclusão: comparando o uso do DTG com o EFV, o EFV aumentou o nível sérico do CT e frações, estaticamente significativa para o HDL. Com uso do DTG, houve um aumento do nível sérico de VLDL e diminuição do HDL, sem significância estatística.
KECENDERUNGAN VISUALISASI ANAK-ANAK DALAM MERESPON SITUASI PANDEMI
Authors: Bastari Rendy Pandita 
Published: April 2022

Abstrak Bahasa visual memiliki efeknya sendiri terhadap audiens. Manifestasi gagasan, ekspresi, ideologi dapat tersalurkan melalui bahasa visual. Hal ini menunjukan bahwa objek visual memiliki makna tertentu, dan terdapat aspek komunikasi yang terkandung di dalamnya. Studi terdahulu menunjukan adanya menifestasi visual pada anak-anak dalam merespon keadaan sosial atau situasi tertentu. Studi ini pun menunjukan bahwa ide yang disampaikan secara visual dapat tercerna dengan baik oleh anak-anak. Studi ini menyimpulkan bahwa proses produksi visual merepresentasikan pengetahuan mereka khususnya secara sosial. Namun studi ini masih belum konklusif terkait kecenderungan karakteristik visualnya. Penelitian ini bermaksud untuk melakukan pendekatan lain dan lebih mengarah pada visualisasinya. Metode yang digunakan adalah analisis visual dari Gillian Rose melalui pengambilan Sampel karya anak-anak dalam merespon situasi pandemi 2020. Sampel berjumlah 18 karya visual dengan kecenderungannya masing-masing. Hasil dari studi ini mendapatkan bahwa anak-anak cenderung merespon dengan visualisasi yang sepenuhnya imajinatif dengan menghadirkan figur-figur dari budaya populer dan ekspresi imajinasinya yang tidak ada konteksnya pada situasi pandemi. Kecenderungan lain terlihat bahwa adanya upaya untuk menggambarkan realita sebagaimana mestinya dan mengandung relevansi terhadap situasi pandemi. Terakhir bahwa terdapat kesan optimisme dalam beberapa karya dan pesimisme dalam beberapa karya. Kata Kunci: anak-anak, karakteristik visual, pandemi, seni AbstractVisual language has its own effect on audiences. The manifestation of ideas, expressions, ideologies can be channeled through visual language. This shows that visual object has a certain meaning, and there are aspects of communication contained in it. Previous studies have shown visual manifestations in children in response to certain social conditions or situations. This study also proves that visually conveyed idea can be received well by children, this study concludes that visual production process represents their social knowledge. However, this study is inconclusive pertaining their visual characteristic tendencies. This study aims to conduct different approach which is more oriented to their visualization. The method used is visual analysis coined by Gillian Rose through sampling of children's work in response to the 2020 pandemic situation. The Sampel consisted of 18 visual works with their respective tendencies. The results of this study show that children tend to respond with fully imaginative visualizations by presenting figures from popular culture and their imaginary expressions that have no context in a pandemic situation. Another trend appears to be an attempt to portray reality as it should and contain relevance to the pandemic situation. Finally, there is an impression of optimism in some works and pessimism in some works. Keywords: art, children, pandemic, visual characteristic
RANCANG BANGUN APLIKASI MARP UNTUK WAYFINDING GEDUNG DAN RUANGAN DI POLINEMA
Authors: Khairy Muhammad Shulhan , Syalwa Laduni Estu , Nurhasan Usman 
Published: April 2022

AbstrakBanyaknya gedung perkuliahan dan kurangnya petunjuk jalan maupun peta lokasi yang mudah diakses membuat lokasi gedung, bangunan, bahkan ruang kelas di Politeknik Negeri Malang (Polinema) mempunyai keterbatasan dalam pencarian. Melihat permasalahan tersebut, maka dibangun sebuah aplikasi pencarian lokasi gedung dan ruangan yang mengacu pada koordinat lokasi yang diperoleh melalui Google Maps. Penelitian ini menggunakan metode Rational Unified Process dengan pendekatan teknologi markerless pada augmented reality sebagai media informasi yang digunakan sebagai penanda gedung dan ruangan yang dapat dijalankan pada smartphone Android. Hasilnya sistem dapat mengimplementasikan metode markerless augmented reality dengan cukup baik yang memperoleh tingkat akurasi 89% dalam ketepatan menampilkan informasi lokasi gedung dan kelas secara real-time pada kamera perangkat android dan dari semua kelas uji. Kata Kunci: android, augmented reality, markerless, wayfinding AbstractThe number of lecture buildings and the lack of street guides and easily accessible location maps make the location of buildings, buildings, even classrooms in Polinema have limitations in the search. This is in accordance with the problems that occur in Polinema's new students in finding the location of each building or class, not least with old students, education personnel, and the public who visit Polinema. Seeing the problem, a search application was built for the location of the building and the room that refers to the coordinates of the location obtained through google map. The study used the Rational Unified Process method with a markerless augmented reality technology as an information medium used as a marker of buildings and rooms that can be run on android smartphones. As a result, the system can implement the Markerless Augmented Reality Method quite well which obtains an 89% accuracy rate in the accuracy of displaying building and class location information in real-time on the cameras of android devices and from all test classes. Keywords: android, augmented reality, markerless, wayfinding
Potensi Beeforage Apis dorsata Binghamii Di KPHP Gularaya Tobimeita Kendari
Authors: Rosmarlinasiah Rosmarlinasiah , Kabe Abigael , Uslinawaty Zakiah , Syamsul Syamsul 
Published: April 2022

Abstrak: Penelitian ini bertujuan untuk mengetahui jumlah dan jenis tumbuhan berbunga, waktu berbunga, dan mengetahui tingkat dominansi jenis tumbuhan berbunga yang berpotensi sebagai beeforage bagi lebah Apis dorsata Binghamii. Penelitian dilaksanakan di Hutan Produksi Tobimeita pada bulan Januari hingga Pebruari 2017, dan lokasi penelitian berada dalam KPHP Gula Raya Kendari,. Metode penelitian menggunakan metode survey, dengan sampel pengamatan menggunakan metode garis berpetak 4 arah mata angin (utara, timur, selatan dan barat ) dan titik pusat pada pohon inang lebah. Data dianalisis menggunakan metode tabulasi dan analisis vegetasi. Hasil penelitian menunjukkan, terdapat 36 jenis tumbuhan berbunga. Tumbuhan yang berbunga sepanjang waktu adalah Aren (Arenga pinnata) sebagai sumber nektar dan pollen, Kasu Manu-Manu (Malatus peniculatus Muell Arg) sebagai sumber pollen, dan Kelapa (Cocos nucifera) sebagai sumber pollen. Jenis tumbuhan yang paling dominan (INP) adalah jenis Rambutan Hutan (Nephelium mutabile) sebagai sumber nektar (46,59%), Eha (Castanopsis buruana) sumber nektar dan pollen (34,54%), Puloli (Quercues celebica) sumber pollen (22,89%), Kapuk Randu (Ceiba pentandra) sumber nektar (20,56%), Toho sumber pollen (18,64%), dan Jambu Mete (Anacardium occidentale) sumber nektar (16,61%). Kata Kunci: Beeforage, Lebah Madu, Apis Dorsata Binghamii, Tumbuhan Berbunga. Abstract: This studi aims to determine the number and species of flowering plants, flowering time, and knowing the level of dominance of flowering plant species which has the potential as bee forage for Apis dorsata Binghamii. The research was carried out in the Production forest of Tobimeita Village, which is within the KPHP Gula Raya Kendari, from January to February 2017. This study used a survey method, the sample of observations using a systematic square gridlines method 4 cardinal directions (north, east, south, west), and the radius center point on the tree where the honeycomb is located. The data were analyzed using tabulation methods and vegetation analysis. The results showed that there were 36 species of flowering plants. Flowering all the time are sugar palm (Arenga pinnata) a source of nectar an pollen, Kasu Manu-Manu (Malatus peniculatus Muell Arg) a source of pollen, and coconut (Cocos nucifera) as a pollen source.The most dominant plant species (important value index) were forest rambutan (Nephelium mutabile) as a source of nectar (46.59%), eha (Castanopsis buruana) as a source of nectar and pollen (34,54%), Puloli (Quercues celebica) as a source of pollen (22,89%), Kapuk Randu (Ceiba pentandra) as a source of nectar (20,56%), Toho(Artocarpus elasticus) (18,64%) as a source of pollen, and jambu mete (Anacardium occidentale) as a source of nectar (16,61%) Keywords: Beeforage, Honeybee, Apis Dorsata Binghamii, Flowering Plant
Predictors of Maternal Death Among Women With Pulmonary Hypertension in China From 2012 to 2020: A Retrospective Single-Center Study
Authors: Dai Ling-Ling , Jiang Tian-Ci , Li Peng-Fei , Shao Hua , Wang Xi , Wang Yu , Jia Liu-Qun , Liu Meng , An Lin , Jing Xiao-Gang , Cheng Zhe 
Published: April 2022

BackgroundPrevious studies have suggested that pregnant women with pulmonary hypertension (PH) have high maternal mortality. However, indexes or factors that can predict maternal death are lacking.MethodsWe retrospectively reviewed pregnant women with PH admitted for delivery from 2012 to 2020 and followed them for over 6 months. The patients were divided into two groups according to 10-day survival status after delivery. Predictive models and predictors for maternal death were identified using four machine learning algorithms: naïve Bayes, random forest, gradient boosting decision tree (GBDT), and support vector machine.ResultsA total of 299 patients were included. The most frequent PH classifications were Group 1 PH (73.9%) and Group 2 PH (23.7%). The mortality within 10 days after delivery was 9.4% and higher in Group 1 PH than in the other PH groups (11.7 vs. 2.6%, P = 0.016). We identified 17 predictors, each with a P-value &lt; 0.05 by univariable analysis, that were associated with an increased risk of death, and the most notable were pulmonary artery systolic pressure (PASP), platelet count, red cell distribution width, N-terminal brain natriuretic peptide (NT-proBNP), and albumin (all P &lt; 0.01). Four prediction models were established using the candidate variables, and the GBDT model showed the best performance (F1-score = 66.7%, area under the curve = 0.93). Feature importance showed that the three most important predictors were NT-proBNP, PASP, and albumin.ConclusionMortality remained high, particularly in Group 1 PH. Our study shows that NT-proBNP, PASP, and albumin are the most important predictors of maternal death in the GBDT model. These findings may help clinicians provide better advice regarding fertility for women with PH.
Radiosurgery in Treatment of Ventricular Tachycardia – Initial Experience Within the Polish SMART-VT Trial
Authors: Kurzelowski Radosław , Latusek Tomasz , Miszczyk Marcin , Jadczyk Tomasz , Bednarek Jacek , Sajdok Mateusz , Gołba Krzysztof S. , Wojakowski Wojciech , Wita Krystian , Gardas Rafał , Dolla Łukasz , Bekman Adam , Grza̧dziel Aleksandra , Blamek Sławomir 
Published: April 2022

BackgroundStereotactic Arrhythmia Radioablation (STAR) is an emerging treatment modality for patients with sustained ventricular tachycardia (VT) and refractory to treatment with drugs and radiofrequency catheter ablation (RFA). It is believed that up to 12–17% of patients experience recurrence of VT within 1 year of follow-up; thus, novel therapeutic options are needed. The aim of this article is to present initial experience within a novel treatment modality for VT.Case SummaryTwo patients with a medical history of coronary artery disease and heart failure with reduced left ventricle (LV) ejection fraction, after implantation of cardioverter-defibrillator (ICD) and previous unsuccessful RFAs owing to sustained VT were admitted to the cardiology department due to recurrence of sustained VT episodes. With electroanatomical mapping (EAM), the VT substrate in LV has been confirmed and specified. In order to determine the target volume for radioablation, contrast-enhanced computed tomography was performed and the arrhythmia substrate was contoured using EAM data. Using the Volumetric Modulated Arc Therapy technique and three 6 MeV flattening filter-free photon beam fields, a single dose of 25 Gy was delivered to the target volume structure located in the apex and anterior apical segments of LV in the first patient and in the apex, anterolateral and inferior apical segments of the second patient. In both cases, volumes of the target structures were comparable. Interrogation of the implanted ICD at follow-up visits throughout 6 months after the treatment revealed no VT episodes in the first patient and sudden periprocedural increase in VT burden with a subsequent gradual decrease of ventricular arrhythmia to only two non-sustained episodes at the end of the follow-up period in case of the second patient. A significant reduction in premature ventricular contractions burden was observed compared to the pre-treatment period. No noticeable deterioration in LV function was noted, nor any adverse effects of radiosurgery associated with the implanted device.ConclusionThe early response to STAR can be unpredictable and probably does not reflect the final outcome of irradiation. Close monitoring of patients, especially in the early period after irradiation is crucial to properly handle potentially harmful early reactions to STAR.
Advanced Clinical Neonatal Nursing Students’ Transfer of Performance: From Skills Training With Real-Time Feedback on Ventilation to a Simulated Neonatal Resuscitation Scenario
Authors: Rød Irene , Jørstad Anna-Kristi , Aagaard Hanne , Rønnestad Arild , Solevåg Anne Lee 
Published: April 2022

BackgroundAdvanced clinical neonatal nurses are expected to have technical skills including bag-mask ventilation. Previous studies on neonatal bag-mask ventilation skills training focus largely on medical students and/or physicians. The aim of this study was to investigate whether advanced clinical neonatal nursing students’ bag-mask ventilation training with real-time feedback resulted in transfer of bag-mask ventilation performance to a simulated setting without feedback on ventilation.Materials and MethodsStudents in advanced clinical neonatal nursing practiced bag-mask ventilation on a premature manikin (Premature Anne, Laerdal Medical, Stavanger, Norway) during skills training. A flow sensor (Neo Training, Monivent AB, Gothenburg, Sweden) was placed between the facemask and the self-inflating bag (Laerdal Medical), and visual feedback on mask leak (%), expiratory tidal volume (VTe in ml/kg), ventilation rate and inflation pressure was provided. Two months later, the students participated in a simulated neonatal resuscitation scenario. The same variables were recorded, but not fed back to the students. We compared ventilation data from skills- and simulation training. A structured questionnaire was used to investigate the students’ self-perceived neonatal ventilation competence before and after the skills- and simulation training.ResultsMask leakage and ventilation rate was higher, and VTe lower and highly variable in the simulated scenario compared with skills training (all p &lt; 0.001). There was no statistically significant difference in inflation pressure (p = 0.92). The fraction of ventilations with VTe within the target range was lower during simulation (21%) compared to skills training (30%) (p &lt; 0.001). There was no difference in the students’ self-perceived competence in bag-mask ventilation before vs. after skills- and simulation training.ConclusionSkills training with real-time feedback on mask leak, ventilation rate, tidal volume, and inflation pressure did not result in objective or subjective improvements in bag-mask ventilation in a simulated neonatal resuscitation situation. Incorrect VTe delivery was common even when feedback was provided. It would be of interest to study whether more frequent training, and training both with and without feedback, could improve transfer of performance to a simulated resuscitation setting.
Evaluation of Essential and Toxic Elements in the Blood of 0–14-Year-Old Children in Hunan, China From 2013 to 2019: A Retrospective Analysis
Authors: Tan Shan , Yang Yang , Chen Zhiheng , Zhao Lingling , Yang Zuocheng , Dai Hongmei , He Wei , Jiang Mei , Yao Yanhua , Huang Ke , Li Liu , Zhu Pengfei , Xu Shasha , Zhao Mingyi , Yang Minghua 
Published: April 2022

ObjectiveThe aim was to investigate the distribution and correlation of Ca, Mg, Zn, Cu, Fe, Pb, and Cd in the blood of children aged 0–14 years in Hunan, China, which may serve to provide a basis for clinical guidance on child health.Study DesignA retrospective analysis was carried out. Concentrations of all elements were determined by atomic absorption spectrophotometry. Distributions were analyzed and compared among different age, sex, and year groups by the Kruskal–Wallis test, the chi-square test, and the Fisher's exact test. Spearman's rank correlation coefficient was used to evaluate the association between every pair of elements.ResultsA total of 46,951 children were involved in this study from 2013 to 2019. The median blood levels of elements were 13.51 μmol/L (Cu), 58.69 μmol/L (Zn), 1.70 mmol/L (Ca), 1.40 mmol/L (Mg), 7.46 mmol/L (Fe), 35.00 μg/L (Pb), and 1.00 μg/L (Cd). Girls had a higher level of Ca and lower levels of Pb and Cd than boys. Cu and Ca showed an upward trend, and Mg and Pb showed a downward trend by year. Zn and Fe increased and Ca decreased significantly with age. The deficiency rates of Fe and Zn decreased significantly by year, while Ca and Cu increased significantly by year. Cd exposure in this area was relatively low.ConclusionMost children had normal levels of the essential elements Ca, Cu, and Mg and the toxic elements Pb and Cd. Severe deficiencies in Zn and Fe were observed in the relatively younger children but improved with age. Persistent efforts in reducing Pb exposure might still be needed.
Evaluation of the Effectiveness of Cochlear Implantation in Children with Severe Sensorineural Hearing Loss
Authors: Асланов П.Р. 
Published: April 2022

Обследовано 87 пациентов в возрасте от 1 года до 12 лет (средний возраст 2,41,2 года) с диагнозом двусторонняя хроническая нейросенсорная потеря слуха IV степени, пограничная с глухотой, состояние после односторонней кохлеарной имплантации . Лица женского пола составили 58,6 (51 человек), мужского 41,4 (36 человек) от общего количества отобранных пациентов. Продолжительность периода глухоты в среднем составила 2,21,7 года (от 6 мес. до 11 лет). В ходе проведенного исследования установлено, что через 3 и 9 месяцев после активации речевого процессора системы кохлеарной имплантации индекс его функционирования во всех группах был низким, однако наименьшие значения зафиксированы в подгруппе IIБ. Усовершенствованный алгоритм настройки речевых процессоров позволяет повысить эффективность реабилитации пациентов после кохлеарной имплантации и дополнить сведения об эффективности функционирования кохлеарного импланта.
87 patients aged from 1 to 12 years (average age 2.41.2 years) were examined with the diagnosis of bilateral chronic sensorineural hearing loss of the IV degree, borderline with deafness, a condition after unilateral cochlear implantation. Women accounted for 58.6 (51 people) and men 41.4 (36 people) of the total number of selected patients. The duration of the period of deafness on average was 2.21.7 years (from 6 months up to 11 years). The study found that 3 and 9 months after activation of the speech processor of the cochlear implantation system, the index of its functioning in all groups was low, but the lowest values were recorded in subgroup II B. The improved algorithm for configuring speech processors allows increasing the efficiency of rehabilitation of patients after cochlear implantation and adding information about the effectiveness of the cochlear implant.