bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estimating the Economic Value of Automated Virtual Reality Cognitive Therapy for Treating Agoraphobic Avoidance in Patients With Psychosis: Findings From the gameChange Randomized Controlled Clinical Trial
Authors: Altunkaya James , Craven Michael , Lambe Sinéad , Beckley Ariane , Rosebrock Laina , Dudley Robert , Chapman Kate , Morrison Anthony , O'Regan Eileen , Grabey Jenna , Bergin Aislinn , Kabir Thomas , Waite Felicity , Freeman Daniel , Leal José 
Published: November 2022

Background
An automated virtual reality cognitive therapy (gameChange) has demonstrated its effectiveness to treat agoraphobia in patients with psychosis, especially for high or severe anxious avoidance. Its economic value to the health care system is not yet established.

Objective
In this study, we aimed to estimate the potential economic value of gameChange for the UK National Health Service (NHS) and establish the maximum cost-effective price per patient.

Methods
Using data from a randomized controlled trial with 346 patients with psychosis (ISRCTN17308399), we estimated differences in health-related quality of life, health and social care costs, and wider societal costs for patients receiving virtual reality therapy in addition to treatment as usual compared with treatment as usual alone. The maximum cost-effective prices of gameChange were calculated based on UK cost-effectiveness thresholds. The sensitivity of the results to analytical assumptions was tested.

Results
Patients allocated to gameChange reported higher quality-adjusted life years (0.008 QALYs, 95% CI –0.010 to 0.026) and lower NHS and social care costs (–£105, 95% CI –£1135 to £924) compared with treatment as usual (£1=US $1.28); however, these differences were not statistically significant. gameChange was estimated to be worth up to £341 per patient from an NHS and social care (NHS and personal social services) perspective or £1967 per patient from a wider societal perspective. In patients with high or severe anxious avoidance, maximum cost-effective prices rose to £877 and £3073 per patient from an NHS and personal social services perspective and societal perspective, respectively.

Conclusions
gameChange is a promising, cost-effective intervention for the UK NHS and is particularly valuable for patients with high or severe anxious avoidance. This presents an opportunity to expand cost-effective psychological treatment coverage for a population with significant health needs.

Trial Registration
ISRCTN Registry ISRCTN17308399; https://www.isrctn.com/ISRCTN17308399

International Registered Report Identifier (IRRID)
RR2-10.1136/bmjopen-2019-031606
Leveraging mHealth and Patient Supporters for African Americans' and Latinxs' Engagement in HIV Care (LEAN): Protocol for a Randomized, Controlled, Effectiveness-Implementation Trial
Authors: Jones Joyce , McKenzie-White Jane , Saxton Ronald , Grieb Suzanne M , Nonyane Bareng , Graham Cadeesha , Cano Anthony , Johnson Sheridan , Childs Lanisha , Greenbaum Adena , Flynn Colin , Pearlowitz Marcia , Celano Shivaun , Chang Larry W , Page Kathleen R 
Published: November 2022

Background
Despite substantial investments in ending the HIV epidemic, disparities in HIV care persist, and there is an urgent need to evaluate novel and scalable approaches to improving HIV care engagement and viral suppression in real-world settings.

Objective
This paper aims to describe a study protocol for a pragmatic type II hybrid effectiveness-implementation randomized controlled trial comparing existing standard of care clinic HIV linkage, adherence, and retention (LAR) protocols to a mobile health (mHealth)–enhanced linkage, adherence, and retention (mLAR) intervention.

Methods
The study will enroll 450 participants from clinics in Baltimore City. Eligibility criteria include being ≥18 years of age, having a new HIV diagnosis or being HIV-positive and out of care, or being HIV-positive and deemed by clinic staff as someone who could benefit from linkage and retention services. Participants randomized to the intervention receive mHealth-supported patient navigation for 12 months. Participants in the control group receive the referring clinic’s standard of care patient support. The primary outcome is HIV virologic suppression at 12 months. A subset of participants will be interviewed at 12 months to learn about their HIV care experiences and, for those in the intervention arm, their experiences with the mLAR intervention. This protocol was developed in collaboration with the Baltimore City Health Department (BCHD) and the Maryland Department of Health (MDH) and with input from a community advisory board.

Results
Enrollment began on February 25, 2020. As of August 11, 2022, 411 of the 450 target participants had been enrolled.

Conclusions
Pragmatic implementation science trials designed with input from key stakeholders, including health departments and community members, can help evaluate the evidence for mHealth interventions to reduce HIV health disparities.

Trial Registration
ClinicalTrials.gov NCT03934437; https://clinicaltrials.gov/ct2/show/NCT03934437

International Registered Report Identifier (IRRID)
DERR1-10.2196/42691
ENERGY MODELLING AND FORECASTING OF DAERAH ISTIMEWA YOGYAKARTA 2025
Authors: Haryono Eko , - Deendarlianto , Sopha Bertha Maya 
Published: November 2022

Daerah Istimewa Yogyakarta (DIY) is one of the provinces in Indonesia which does not have a backup or potential sources of non-renewable primary energy. The non-renewable energy demand until this time, such as oil,coal and gas is supplied from the outside. DIY is in Java Madura Bali (JAMALI) interconnerction system and has not had a large-scale power systems. While DIY has renewable energy sources such as hydro, solar, wind, wave and biomass energy. These renewable energy sources are alternative energy that have not been optimally used. The lack of reserve energy resources that resulting dependence of energy supply from other areas should receive special attention from DIY government. To meet energy demand, the energy resources development is required. Due to the energy resources development requires a long time and high cost, it is necessary to be supported by good planning in energy policy.The purpose of this study is to determine the balance of energy demand and supply of DIY until 2025. Furthermore, the purpose of this study is to find out a mix number of renewable energy. The Indonesian government has launched a vision of 25/25 which expection in 2025, the mix number of renewable energy will be 25%.The results of this study indicate that in 2025, the Transportion Sector is the largest energy user sector in DIY at 52.37%, followed by Household Sector (32.70%), Commercial Sector (8.26%), Other Sector (4.64%), and Industrial Sector (2.04%). The high level of energy consumption in the Transportation Sector is caused by the increasing number of vehicles especially motorcycles and passenger cars considering DIY is a student and tourism city. In term of the type of energy used, in 2025, the gasoline is the greatest type of energy demand (41.8%), followed by LPG (23.97%), electricity (18.14%) and diesel oil (11, 74%). This indicates that the fuel oil is still the main energy source for the DIY community activities. When viewed from supply side, most of the energy needs in DIY are supplied from outside. If the development of enewable energy targets DIY reached, the renewable energy mix is obtained by 0.53 %.
The Impact of Carbamylation and Anemia on HbA1c’s Association With Renal Outcomes in Patients With Diabetes and Chronic Kidney Disease
Authors: Tang Mengyao , Berg Anders , Rhee Eugene P. , Allegretti Andrew S. , Nigwekar Sagar , Karumanchi S. Ananth , Lash James P. , Kalim Sahir 
Published: November 2022

OBJECTIVE
Glycated hemoglobin (HbA1c) can predict risk for microvascular complications in patients with diabetes. However, HbA1c’s reliability in chronic kidney disease (CKD) has been questioned, with concerns including competition from another posttranslational protein modification, carbamylation, acting on the same amino groups as glycation, and anemia with reduced erythrocyte lifespans leading to altered glycation accumulation. We investigated whether carbamylation and anemia modify the impact of HbA1c on renal outcomes in patients with diabetes and CKD.

RESEARCH DESIGN AND METHODS
In 1,516 participants from the Chronic Renal Insufficiency Cohort study with diabetes and CKD, Cox regression models were applied to evaluate the association between HbA1c and CKD progression (composite of end-stage kidney disease or 50% decline in estimated glomerular filtration rate [eGFR]), stratified by carbamylated albumin (C-Alb) quartiles and anemia.

RESULTS
The mean eGFR was 38.1 mL/min/1.73 m2, mean HbA1c was 7.5% (58 mmol/mol), and median C-Alb was 8.4 mmol/mol. HbA1c was lower in the higher C-Alb quartiles. During a median follow-up of 6.9 years, 763 participants experienced CKD progression. Overall, higher HbA1c was associated with an increased risk of CKD progression (adjusted hazard ratio 1.07 [95% CI 1.02–1.13]). However, using stratified analyses, HbA1c was no longer associated with CKD progression in the highest C-Alb quartile, but did show a monotonic increase in CKD progression risk across each lower C-Alb quartile (P-interaction = 0.022). Anemia also modified the association between HbA1c and CKD progression (P-interaction = 0.025).

CONCLUSIONS
In patients with coexisting diabetes and CKD, the association between HbA1c and CKD progression is modified by carbamylation and anemia.
Analisis Determinan Harga Beras di Kabupaten Padang Pariaman
Authors: Lestari Indah , Marta Joan , Satria Doni 
Published: November 2022

This study aims to analyze; (1) the impact of the amount of rice production on the rice price in Padang Pariaman (2) the effect of dry threshed paddy (Gabah Kering Panen/GKP) price on the rice price in Padang Pariaman (3) the effect of unhusked dry rice ready for milling (Gabah Kering Giling/GKP) price on the rice price in Padang Pariaman (4) the influence of the Pekanbaru rice price on the Padang Pariaman rice price. The data used is monthly from 2018-2020. Analysis used analysis Ordinary Least Square (OLS). The results showed that (1) the amount of rice production had a negative and significant effect on the price of rice in Padang Pariaman (2) the price of GKP had a positive and significant impact on the price of rice in Padang Pariaman (3) the price of GKG had a positive and significant effect on rice prices. significant effect on rice prices in Padang Pariaman (4) Pekanbaru rice prices have a positive and significant impact on Padang Pariaman rice prices
Pengaruh Investasi (PMDN), Angkatan Kerja, Pengeluaran Pemerintah dan Pendidikan Terhadap Pertumbuhan Ekonomi di Indonesia
Authors: Fadillah Mia , Anis Ali 
Published: November 2022

The purpose of this research is to figure out (1) The Influence of investment to the growth economic in Indonesia (2) The Influence of the quantity of workforce, to the growth economic in Indonesia (3) The Influence of goverment expenditure to the growth economic in Indonesia (4) The Influence of education to the growth economic in Indonesia (5) The Influence of investment, the workforce, goverment expenditure and education to the growth economic in Indonesia. This research uses panel data from 2010-2019, the method is multiple linear regression. the research shows The estimation multiple linear regression (OLS) with the Fixed Effect Model that shows: (1) investment had an possetive significant influence to the growth economic in Indonesia(2) the workforce had an possetive significant influence to the growth economic in Indonesia (3) goverment expenditure had an possetive significant influence to the growth economic in Indonesia (4) education had a negative significant influence to the growth economic in Indonesia. Based on this research the writer suggests to increase the quality of investment, the workforce , goverment expenditure and education. The government should cooperate strongly with tne participant countries and take action to increase the productivity and the quality of the human sources also increase the investment that makes increase the growth economic in Indoneisa.
The influence of precedent practice of the European Court of Human Rights on the civil justice of Ukraine
Authors: Rohach O. , Fennych V. 
Published: November 2022

This article examines the influence of the decisions of the European Court of Human Rights on the development of the civil procedural law of Ukraine and the practice of applying its norms by domestic courts. The concept and essence of the precedent nature of decisions (decisions) of the European Court of Human Rights, their place in the system of so-called "judicial sources" of civil procedural law are defined. The shortcomings of the Law of Ukraine "On the implementation of decisions and application of the practice of the European Court of Human Rights" are indicated, which recognizes the practice of the European Court of Human Rights as a source of law and the position of domestic courts regarding this deficiency.
It is noted that the source of law according to the Law of Ukraine "On the Execution of Decisions and Application of the Practice of the European Court of Human Rights" is also the practice of the European Commission on Human Rights and its role in the procedure for considering complaints about violations of the Convention is determined.
The directions of the influence of the practice of the European Court of Human Rights on civil proceedings are outlined, where it is concluded that a precedent can be formed on any procedural issue due to the dynamic interpretation by the specified court of the provisions of the Convention on the Protection of Human Rights and Fundamental Freedoms of 1950 and its protocols . It is noted that the practice of the European Court of Human Rights generally constructs legal ideas regarding the principles of civil procedure and the right to a fair trial. On the example of a separate decision of the European Court of Human Rights, the law enforcement and regulatory influence on the results of consideration and resolution of a civil case and the development of the civil procedural law of Ukraine, respectively, are analyzed. The importance of the practice of the European Court of Human Rights for the civil justice of Ukraine is summarized. In particular, taking into account the precedent practice of the ECtHR during the consideration and resolution of civil cases will eliminate the factors that serve as the reason for the appeal to the Court and will introduce European standards of protection of human rights and freedoms into Ukrainian civil proceedings. As a result, the impact of the decisions of the ECtHR will reduce the need to appeal to an international judicial institution in search of just satisfaction, which will accelerate the protection of the rights and freedoms of the parties to a civil case within the framework of national judicial jurisdiction.
The genesis of the European Parliament and its transformation to supra statehood
Authors: Hrebeniuk D. 
Published: November 2022

The article examines the European Union as a unique association of European countries, which was created as an organizational form for political, economic and social cooperation between member countries, candidates for membership and partner countries that are not part of the union. The European Union symbolizes the diversity of nations and European cultures and aims to achieve peace and prosperity. Independent countries united for the sake of a common goal and sacrificed part of their sovereignty in order to become economically stronger, so it is not surprising that the official motto of the union is "unity in diversity".
The article pays special attention to the nature of the European Union, because de facto it is an international entity, it combines such features as supra-statehood and inter-statehood, but de jure it is neither one nor the other. The structure of the European Union includes institutions whose tasks are to realize the goals of this union, to serve its interests and the interests of its citizens, as well as to ensure the consistency and effectiveness of its policies. At the beginning of its creation, the European Union consisted of six countries and had a completely different name, namely the European Coal and Steel Association. Gradually, the subjects of this entity are deepening economic integration and creating a single market, we can also see that successively, partial management functions are moving to the supranational level and the number of future participants of the union is increasing. The evolution of the union takes place for the sake of economic development, through the opening of markets, which leads to an increase in production and, as a result, new working cities are created. With an increase in imports, competition increases and prices decrease and the quality of goods increases [1, р. 1].
This scientific work examines the formation of the legislative institution of the European Union, analyzes the cooperation of the European Parliament with other leading institutions, and also examines the regulatory and legal framework that influenced the transformation and reveals the nature of the European Parliament.
BETWEEN THE LIGHTNESS OF BEING AND THE WEIGHT OF BECOMING
Authors: FLOREA Marius 
Published: November 2022

One of the few direct solutions that Nietzsche gives for the overcoming of nihilism is the facing of the thought of eternal recurrence. Being the heaviest of all thoughts, it may seem that through Heidegger’s filter it will become a sort of metaphysical concept, but his analysis may at least help us see it as an axis around which thought can pivot, at least for a moment. Kundera sees the contradiction between lightness and weight as the most problematic of all, as it is difficult to see the burden as something positive when emancipation seems to always be an attempt to achieve total freedom, a search for lightness. We argue that the heavy thought makes us confront fatalism and affirm freedom, while lightness makes freedom by becoming impossible. The eternal recurrence is the idea that offers motivation to intervene in the chain of determinations and to influence them decisively.
Morfologi Kisah Negreri Jambi (Putri Pinang Masak): Model Analisis Vladimir Propp
Authors: Septiani Resty Maudina 
Published: November 2022

MORFOLOGI KISAH Abstrak: Penelitian ini bertujuan menganalisis morfologi cerita rakyat Jambi Putri Pinang Masak. Ada berbagai versi Putri Pinang Masak yang dikenal di Riau, Jambi, dan Sumatera Selatan. Peneliti akan menggunakan versi Kisah Negeri Jambi yang telah didokumentasikan dalam bentuk tulisan oleh Amran Tasai. Fokus objek yang diteliti meliputi fungsi-fungsi pelaku, skema dan pola cerita, dan distribusi fungsi di kalangan pelaku. Tujuan penelitian ini adalah mengetahui struktur cerita rakyat ini. Model analisis yang dikembangkan Vladimir Propp digunakan dalam penelitian ini. Metode yang digunakan adalah metode deskriptif kualitatif dengan teknik pengumpulan data melalui studi pustaka dan analisis struktural naratologi. Hasil analisis menunjukkan ada sebelas fungsi yaitu Absentation (β), Delivery (ζ), The difficult task (M), Struggle (H), Fraud (ƞ), Return (↓), Villainy (Α), lack (a), Victory (I), Marking (J), dan The initial misfortune or lack is liquated (K). Fungsi terebut terdistribusi ke dalam tiga lingkaran tindakan, yaitu lingkaran aksi penjahat, aksi donor, dan aksi perantara. Kata kunci: morfologi, Kisah Negeri Jambi, Putri Pinang Masak, fungsi pelaku, Vladimir Propp, deskriptif kualitatif.Abstract: This study aims to analyze the morphology of Jambi’s folklore of Putri Pinang Masak. The story of Putri Pinang Masak varys in Riau, Jambi, and South Sumatera. However, the documented Kisah Negeri Jambi by Amran Tasai is selected. Narrative functions, schemes and the patterns of the story, and function distributions among characters are observed. This study is intended to find out the structure of the story. The Analysis’s model by Vladimir Propp is used to achieve the author’s target. This study uses qualitative approach of narratological analysis and literature studies. The result showed that there are eleven narrative functions which are Absentation (β), Delivery (ζ), The difficult task (M), Struggle (H), Fraud (ƞ), Return (↓), Villainy (Α), lack (a), Victory (I), Marking (J), dan The initial misfortune or lack is liquated (K). The narrative functions are distributed in three spheres of action which are villain action, donor action, and dispatcher action. Keywords: morphology, Kisah Negeri Jambi, Putri Pinang Masak, narrative functions, Vladimir Propp, descriptive qualitative.
Microbial Contamination after Cardiac Surgery in a Hospital Cardiac Surgery Ward
Authors: Damavandi Donya Shahedi ,   Faculty of Medicine, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran, Javan Mina ,   Faculty of Medicine, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran, Moshashaei Hamidreza ,   Faculty of Medicine, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran, Forootan Mojgan ,   Department of Gastroenterology, Gastrointestinal and Liver Diseases Research Center (RCGLD),Shahid Beheshti University of Medical Sciences, Tehran, Iran, Darvishi Mohammad ,   Infectious Diseases and Tropical Medicine Research Center (IDTMRC), Department of Aerospace and Subaquatic Medicine,AJA University of Medical Sciences, Tehran, Iran,   Mohammad Darvishi, Infectious Diseases and Tropical Medicine Research Center (IDTMRC), Department of Aerospace and Subaquatic Medicine,AJA University of Medical Sciences, Tehran, Iran E-mail: darvishi1349@gmail.com Phone: 00989123060846
Published: November 2022

Surgery site infection is one of the most common postoperative complications which is associated with increased morbidity, mortality and admission costs. It is considered a priority to determine the level of nosocomial infection and its control in reflecting the quality of care. Therefore, this study aimed to evaluate the microbial contamination after cardiac surgery at a hospital cardiac surgery ward of Besat Hospital, Tehran.
In this cross-sectional descriptive-analytic study (2013-2017), 610 patients underwent surgery at the Department of Cardiac Surgery of Besat Hospital. All necessary information such as urine culture, surgical site, histopathologic examination for the diagnosis of microbial contamination and microorganisms were collected from the patient records and inserted in the questionnaire. The data were analyzed using SPSS (version 25).
The incidence of nosocomial infections following cardiac surgery reportedly ranged from 17% to 23%. Accordingly, pneumonia (51.2%) and local infections (22%) were the most common infections in the studied population. The mortality rate in our population was 11.4%. Moreover, 64.3% of the total mortality cases were reported in patients with sepsis. The mean age and duration of admission of patients with catheter infection were significantly higher than other subjects.
Given the relatively high prevalence of the infection and its importance, it is necessary to take more serious measures to prevent and control these infections.