bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-wave infrared transparent sulfur polymers enabled by symmetric thiol cross-linker
Authors: Lee Miyeon , Oh Yuna , Yu Jaesang , Jang Se Gyu , Yeo Hyeonuk , Park Jong-Jin , You Nam-Ho 
Published: December 2022

Abstract
Infrared (IR) transmissive polymeric materials for optical elements require a balance between their optical properties, including refractive index (n) and IR transparency, and thermal properties such as glass transition temperature (Tg). Achieving both a high refractive index (n) and IR transparency in polymer materials is a very difficult challenge. In particular, there are significant complexities and considerations to obtaining organic materials that transmit in the long-wave infrared (LWIR) region, because of high optical losses due to the IR absorption of the organic molecules. Our differentiated strategy to extend the frontiers of LWIR transparency is to reduce the IR absorption of the organic moieties. The proposed approach synthesized a sulfur copolymer via the inverse vulcanization of 1,3,5-benzenetrithiol (BTT), which has a relatively simple IR absorption because of its symmetric structure, and elemental sulfur, which is mostly IR inactive. This strategy resulted in approximately 1 mm thick lenses with an ultrahigh refractive index (nav>1.9) and high mid-wave infrared (MWIR) and LWIR transmission, without any significant decline in thermal properties. Furthermore, we demonstrated that our IR transmissive material was sufficiently competitive with widely used optical inorganic and polymeric materials.
Primary extraskeletal myxoid chondrosarcoma of ovary with novel KIT mutation: A case report and literature review
Authors: Liu Fang , Xiong Jianbo , Peng Yi , Li Wen , Zhou Enle , Zhong Shanshan , Li Mingyang , Jiang Weiyang , Jiang Qingming 
Published: December 2022

Abstract
Background
Extraskeletal myxoid chondrosarcoma (EMC) is a rare malignant mesenchymal neoplasm of uncertain differentiation. Despite its name, this tumor type has no relationship to cartilage. Most tumors arise in deep soft tissue of the proximal extremities and limb girdles. The KIT mutation of this tumor is extremely rare and the ovary location as primary location has not been reported yet before.
Case presentation:
We present a case of primary EMC of ovary with novel KIT mutation of a 54-year-old female. To the best of our knowledge, we report the first primary EMC of ovary and the fourth case with KIT mutation.
Conclusions
With this case study we try to make a better understanding of tumor, lessen the diagnostic confusion by highlighting its rare location, and more importantly present substantial molecular data, which might help in providing more therapeutic opportunities in the future.
Beneficial Methanolic Extraction of Aractium lappal and Eryngium billardieri that Have Potential of Anti diabetic, Antibacterial, Anticancer and Biosynthesis of Novel Silver Nanoparticles
Authors: Feizi Hassan , Mollania Nasrin , Mollania Hamid , Mollania Fariba 
Published: December 2022

Abstract
Biomass wastes and medical plants extract have been demonstrated to be sufficient sources for the biosynthesis of nanoparticles using green technology, and has been applied in bio-medical and technology fields. Nanotechnology is gaining tremendous impetus in the present century due to its capability of modulating metals into the nanosize scale, which drastically changes the chemical, physical and optical properties of metals. This study reports the optimal conditions for beneficial extraction of Aractium lappal and Eryngium billardieri and biosynthesis of silver nanoparticles through reduction of Ag+ ions by secondary metabolite of plant extrcts. The purified nanoparticles was further characterized by UV–vis spectra, dynamic light scattering (DLS), energy dispersive X-Ray Analysis (EDX), X Ray Diffraction (XRD) and Field-Emission Scanning Electron Microscopy (FESEM). Results showed that, the purified solution yielded the maximum absorbance peak at 426 nm and the DLS characterization showed a uniform distribution of nanoparticles, with an average size of 47 nm. In addition, antibacterial results show that these compounds, have good potential of antibacterial activity against Gram negative and Gram positive bacteria. Finally, the cytotoxicity effect of silver nanoparticles on viability of MCF7 and MCR-5 cell lines was assessed by cytotoxicity 2,5-diphenyl-2H-tetrazolium bromide (MTT) assay. The results show that toxicity of the optained nanoparticles on cells is very low (IC50, MCF-7 > 1 mg/ml and IC50, MCR−5 > 5 mg/ml) and follows a concentration dependent manner. Furthermore, the antioxidant and anti-diabetic effect of Aractium lappal methanolic extract were also investigated. The inhibition of pancreatic αft-amylase using this extract seems to be a good way to treat diabetes. Our findings indicate that these extracts are worthy of further consideration as plant drug to develop a new class of inhibitors against bacteria, some cancerous cell lines and also due to considerable antidiabetic effects and nanoparticles biosynthesis potential.
Wirsung diameter and microchannel presence as risk factors in postoperative pancreatic fistulas
Authors: doğan caner , borazan ersin , baskonus ilyas , dizibüyük Omer , balik ahmet 
Published: December 2022

Abstract
Background
Postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is one of the most severe morbidities, which can occasionally be fatal. This study evaluated the association of the main pancreatic duct diameter and the presence of open pancreatic interlobular ducts (microchannels) of the pancreas with pancreatic fistula in the pancreaticojejunostomy anastomotic line.
Methods
An evaluation was made on pancreatojejunostomy anastomoses of 49 patients who underwent pyloric-preserving PD between March 2018 and October 2019 using the International Study Group of Pancreatic Fistula classification. Demographic, clinical, intraoperative, and pathological characteristics of patients without postoperative fistula and with grade A fistula (biochemical leak) were recorded. The groups were analyzed for the diameter of the duct of Wirsung and the presence of microchannels on the cross-sectional surface of the pancreatic surgical margin through the PD materials.
Results
Drain fluid amylase levels were more than three times higher than blood amylase levels in 32(65.3%) patients. The diameter of the duct of Wirsung in overall patients was 2.97±1.84cm. Patients with a small main pancreatic duct diameter(<3 mm) had a high risk of a biochemical leak(RR:2.38;95% CI:1.14–4.97; p:0.002). Microchannels were detected in 27(55.1%) patients. The risk of a leak was 2.45 times higher in patients with microchannels on the pancreatic cross-sectional surface (RR:0.409;95% CI:0.23–0.72;p:0.001).
Conclusion
A main pancreatic duct diameter of < 3 mm, and the presence of microchannels on the pancreatic cross-sectional surface may increase the risk of fistula in postoperative pancreaticojejunostomy anastomosis. Thus, it should be considered in the management of patients at risk after pancreaticoduodenectomy.
Strong Pareto-based multiobjective differential evolution algorithm
Authors: Wang Lifang , Zhang Zhe , Guo Xiaodong , Sun Chaoli , Lan Yang 
Published: December 2022

Abstract

SPEA2 is a multiobjective optimization algorithm based on the Pareto advantage. Since SPEA2 uses traditional genetic operators, the algorithm cannot solve problems in various complex scenarios. For this reason, this article proposes a multiobjective differential evolution algorithm based on strong Pareto (SPEA2-DE) to solve the above problem with several main strategies. First, the new proposed mechanism divides individuals into nondominated and dominated individuals, and it uses a difference operator based on the optimal vector for nondominated individuals to improve the local exploitation capability. To improve the global exploration capability for dominated individuals, this mechanism also uses a difference operator that is based on the current vector and the optimal individual. Second, the learning factor uses an adaptive strategy based on individual adaptation values to improve both the global exploration capability and the local exploitation capability. Furthermore, an adaptive parameter strategy for crossover probabilities for different evolutionary stage characteristics is employed to improve convergence. Third, the improved environmental selection strategy in SPEA2 makes full use of individual density information to increase population diversity, and the convergence of the proposed algorithm is analyzed. To evaluate the performance of SPEA2-DE, comparison experiments are conducted with six state-of-the-art multiobjective algorithms to solve 16 functions in the DTLZ and WFG benchmark suite and address five real-world engineering application scenarios. The comparison results indicate that the proposed SPEA2-DE is significantly better than, or at least comparable to, its competitors.
Passivation Remediation of Cadmium Contaminated Soil by Polyethyleneimine Modified Biochar
Authors: LI Haihua , Qu Yuanyuan , Wang Zhichen , Xie Minghao 
Published: December 2022

Abstract
Biochar was prepared from tobacco straws, and polyethyleneimine (PEI) was loaded on the biochar surface to produce PEI-modified biochar (PBC). The remediation effect of PBC on Cd-contaminated soil was studied. During the soil incubation, soil samples were collected three times at 30, 60 and 90 days, and the physical and chemical properties of soil and the contents of heavy metals were determined after natural drying. After conducting passivation and remediation of Cd-contaminated soil, the available Cd content decreased significantly, the residual and oxidizable heavy metal Cd contents in the soil increased significantly, and the weak acid extractable Cd content decreased. When the PBC addition amount was 3% and the soil was cultured for 90 d, the available Cd content in the soil decreased by 54.36%, the weak acid extractable Cd content decreased by 35.36%, and the residual Cd content increased by 184.67%. This indicates that PBC can be used to repair heavy metal-contaminated soil and reduce the bioavailability, migration, and transformation ability of heavy metal Cd.
A comparative study of data-driven modal decomposition analysis of unforced and forced cylinder wakes
Authors: Chang Xu , Chen Wen-Li , Li Hui , Gao Donglai 
Published: December 2022

Abstract
The present study on the recognition of coherent structures in flow fields was conducted using three typical data-driven modal decomposition methods: proper orthogonal decomposition (POD), dynamic mode decomposition (DMD), and Fourier mode decomposition (FMD). Two real circular cylinder wake flows (forced and unforced), obtained from two-dimensional particle image velocimetry (2D PIV) measurements, were analyzed to extract the coherent structures. It was found that the POD method could be used to extract the large-scale structures from the fluctuating velocity in a wake flow, the DMD method showed potential for dynamical mode frequency identification and linear reconstruction of the flow field, and the FMD method provided a significant computational efficiency advantage when the dominant frequency of the flow field was known. The limitations of the three methods were also identified: the POD method was incomplete in the spatial-temporal decomposition and each mode mixed multiple frequencies leading to unclear physics, the DMD method is based on the linear assumption and thus the highly nonlinear part of the flow field was unsuitable, and the FMD method is based on global power spectrum analysis while being overwhelmed by an unknown high-frequency flow field.
Responding to the Tragedies of Our Time - The Human Right to Health and the Virtue of Creative Resolve
Authors: Hassoun Nicole 
Published: December 2022

We live in tragic times. Millions are sheltering in place to avoid exacerbating the Coronavirus (COVID-19) pandemic. How should we respond to such tragedies? This paper argues that the human right to health can help us do so because it inspires human rights advocates, claimants, and those with responsibility for fulfilling the right to try hard to satisfy its claims. That is, the right should, and often does, give rise to what I call the virtue of creative resolve. This resolve embodies a fundamental commitment to finding creative solutions to what appear to be tragic dilemmas. Contra critics, we should not reject the right even if it cannot tell us how to ration scarce health resources. Rather, the right gives us a response to apparent tragedy in motivating us to search for ways of fulfilling everyone’s basic health needs.
Impacts of disinfected wastewater irrigation on soil characteristics, microbial community composition, and crop yield
Authors: Leonel Lays Paulino , Bize Ariane , Mariadassou Mahendra , Midoux Cédric , Schneider Jerusa , Tonetti Adriano Luiz 
Published: December 2022

AbstractFor agricultural reuse, the disinfection treatment must be efficient to inactivate the resistant pathogens and must not generate harmful byproducts for the soil and crop production. Thus, the aim of this work was to evaluate the possible impacts caused by the irrigation with wastewater disinfected with sodium hypochlorite, peracetic acid, ultraviolet radiation, or the oxidation process UV radiation combined with hydrogen peroxide over soil physicochemical properties and microbial community composition, as well as over the wheat crop yield in the short term. A pot essay was performed in a greenhouse, and at the end the main alterations observed in soil physicochemical properties were due to water type, not to the disinfection treatments. The crop yield was influenced by the water type, but not by the disinfectant treatments. Irrigation with wastewater improved almost 5 times the wheat grains yield, compared with freshwater. Wastewater irrigation increased the abundance of families involved in organic matter degradation and nitrogen cycle, and some pathogenic bacteria. Among the disinfectant treatments, the UV disinfection played an important role in shaping soil bacterial community structure.
Impact evaluation and analysis at a river basin scale under projected climate and land-use change
Authors: S. Saranya M. , Nair Vinish V. 
Published: December 2022

Abstract
This study evaluated the individual as well as integrated impacts of climate and land use change on streamflow over Meenachil River Basin, Kerala, India. The hydrological model SWAT was used to simulate future streamflow simulations under representative concentration pathway (RCP) 4.5 and 8.5 scenarios for the medium term (2025–2055) and long term (2056–2086). The land use land cover change was projected using land change modeler (LCM) of TerrSet software for the future period. Climate model simulations were taken to predict future streamflow at the regional scale, and an attempt was made to reduce the uncertainty associated with future predictions. According to the findings, streamflow was influenced by climate change (68.07%) and land use change (31.92%), with climate change having a higher contribution rate. The findings suggest that the combined impact of climate and land use change would increase streamflow in the future. The annual average streamflow is expected to decline (5.9%) in the medium term (2025–2055) under RCP 4.5 scenario and rise by 5.3% under RCP 8.5 scenario with reference to the observed streamflow for the period 1987–2017. However, in the long term, it is expected to rise by 10.56% under RCP 4.5 and 22.61% under RCP 8.5.
Prediction of Partition Coefficient of Carbamates using GA-MLR and GAANN
Methods, and Comparison with Experimental Data
Authors: Moosavi Seyedeh Azadeh , Mohammadinasab Esmat , Isfahani Tahereh Momeni 
Published: December 2022

Abstract:
In the present study, quantum mechanics calculations at the B3LYP theory level and 6-
31G* basis set were carried out to obtain the optimized geometry of carbamates. Then, a comprehensive
set of molecular descriptors was computed by using the Dragon software. A genetic algorithm
(GA) was also applied to select the suitable variables that resulted in the best-fixed models. The relationship
between the molecular descriptors and the partition coefficient of 66 types of carbamates is
represented. The molecular descriptors were applied for modeling the multiple linear regression
(MLR) and artificial neural network (ANN) methods. The quantitative structure-property relationship
models showed that the GA-ANN over the GA-MLR approach resulted in the best outcome. So, the
predicted partition coefficient was found to be in good agreement with the experimental partition coefficient.
The EEig01x and ALOGP descriptors were applied for modeling the multiple linear regression
(MLR) and artificial neural network (ANN) methods. The best model was validated by Q2
LOO,
Q2
F1, Q2
F2, Q2
F3, and CCC techniques and external validation parameters for the established theoretical
models.
Hereditary Rickets: A Quick Guide for the Pediatrician
Authors: AlSubaihin Abdulmajeed , Harrington Jennifer 
Published: December 2022

Abstract:
With the increased discovery of genes implicated in vitamin D metabolism and the regu-lation of calcium and phosphate homeostasis, a growing number of genetic forms of rickets are now recognized. These are categorized into calciopenic and phosphopenic rickets. Calciopenic forms of hereditary rickets are caused by genetic mutations that alter the enzymatic activity in the vitamin D activation pathway or impair the vitamin D receptor action. Hereditary forms of phosphopenic rick-ets, on the other hand, are caused by genetic mutations that lead to increased expression of FGF23 hormone or that impair the absorptive capacity of phosphate at the proximal renal tubule. Due to the clinical overlap between acquired and genetic forms of rickets, identifying children with hereditary rickets can be challenging. A clear understanding of the molecular basis of hereditary forms of rick-ets and their associated biochemical patterns allow the health care provider to assign the correct di-agnosis, avoid non-effective interventions and shorten the duration of the diagnostic journey in these children. In this mini-review, known forms of hereditary rickets listed on the Online Mendeli-an Inheritance in Man database are discussed. Further, a clinical approach to identify and diagnose children with hereditary forms of rickets is suggested.
First Trimester Tricuspid Regurgitation: Clinical Significance
Authors: Teixeira Sofia , Guedes-Martins Luís. 
Published: December 2022

Abstract:
Tricuspid regurgitation is a cardiac valvular anomaly that consists of the return of blood
to the right atrium during systole due to incomplete valve closure. This structure can be visualized
on ultrasound between 11 and 14 weeks of gestation in most cases. Despite being a common finding,
even in healthy fetuses, the presence of tricuspid regurgitation may be associated with chromosomal
and structural abnormalities. The evaluation of tricuspid flow and the presence of regurgitation
on first-trimester ultrasound has shown promising results regarding its role in the early detection
of aneuploidies, congenital heart defects, and other adverse perinatal outcomes. This review
article aims to demonstrate the importance of tricuspid regurgitation as a secondary marker, and
consequently, significant benefits of its early detection when added to the combined first-trimester
screening. Its value will be discussed, namely its sensitivity and specificity, alone and together
with other current markers in the fetal assessment performed in the first-trimester ultrasound.
Adaptogenic Properties of 1-(Germatran-1-il)-Oxyethylamine
Authors: Zhigacheva Irina V. , Krikunova Natalya I. , Rasulov Maksud M. 
Published: December 2022

Background:
Germanium is a biologically active trace element, and it is present in almost
all organs and tissues. Its biological activity was revealed in the 20th century. However, the study on
the possibility of using germanium for medical purposes was first undertaken by the Japanese scientist
Dr. Kazuhiko Asai in 1940. In 1965, academician M.G.Voronkov and colleagues synthesized tricyclic
esters of triethanolamine germanium with the general formula XGe(OCH2CH2)3N and studied their
biological activity. However, the adaptogenic properties of these compounds have not been sufficiently
studied. In this regard, there is an urgent need to study the adaptogenic properties of these drugs.

Objective:
As the resistance of the organism to stress factors primarily depends on energy metabolism,
the aim of our work was to study the influence of stress and 1- (germatran-1-il) –oxyethylamine (GM)
on the functional state of mitochondria.

Methods:
The functional state of mitochondria was studied as per the rate of mitochondria respiration
by the level of lipid peroxidation and fatty acid composition of mitochondrial membranes by chromatography
technique.

Results:
It was shown that the drug in concentrations of 10-5, 10-6, and 10-11M reduced the intensity of
LPO in the membranes of "aged" mitochondria. This may serve as evidence regarding the presence of
anti-stress properties in the drug. Injection of GM at a dose of 10-5 mol/kg to rats prevented the activation
of LPO in the membranes of the liver mitochondria in conditions of acute hypobaric hypoxia. Restricting
lipid peroxidation, GM prevented changes in the content of C18 and C22 fatty acids in mitochondrial
membranes, which probably contributed to maintaining the bioenergetic characteristics of
mitochondria at the control level.

Conclusion:
It is assumed that the anti-stress activity of the drug is associated with its antioxidant
properties and its effect on the complex I of the mitochondrial respiratory chain.