bluuebunny/crossref_metadata_2025_split huggingface dataset:
North American multicenter experience with the Flow Redirection Endoluminal Device in the treatment of intracranial aneurysms
Authors: Khorasanizadeh MirHojjat , Shutran Max , Schirmer Clemens M. , Salem Mohamed M. , Ringer Andrew J. , Grandhi Ramesh , Mitha Alim P. , Levitt Michael R. , Jankowitz Brian T. , Taussky Philipp , Thomas Ajith J. , Moore Justin M. , Ogilvy Christopher S. 
Published: September 2022

OBJECTIVE
Flow diverters have revolutionized the endovascular treatment of intracranial aneurysms. Here, the authors present the first large-scale North American multicenter experience using the Flow Redirection Endoluminal Device (FRED) in the treatment of cerebral aneurysms.

METHODS
Consecutive cerebral aneurysms treated with FRED at 7 North American centers between June 2020 and November 2021 were included. Data collected included patient demographic characteristics, aneurysm characteristics, periprocedural and long-term complications, modified Rankin Scale (mRS) scores, and radiological follow-up.

RESULTS
In total, 133 aneurysms in 116 patients were treated with 123 FRED deployment procedures and included in this study. One hundred twenty-six aneurysms (94.7%) were unruptured, 117 (88.0%) saccular, and 123 (92.5%) located in anterior circulation. The mean (range) aneurysm maximal width and neck width sizes were 7.2 (1.5–42.5) mm and 4.1 (1.0–15.1) mm, respectively. Successful FRED deployment was achieved in 122 procedures (99.2%). Adjunctive coiling was used in 4 procedures (3.3%). Radiological follow-up was available for 101 aneurysms at a median duration of 7.0 months. At last follow-up, complete occlusion was observed in 55.4% of patients, residual neck in 8.9%, and filling aneurysm in 35.6%; among cases with radiological follow-up duration > 10 months, these values were 21/43 (48.8%), 3/43 (7.0%), and 19/43 (44.2%), respectively. On multivariate regression analysis, age (OR 0.93, p = 0.001) and aneurysm neck size (OR 0.83, p = 0.048) were negatively correlated with odds of complete occlusion at latest follow-up. The retreatment rate was 6/124 (4.8%). The overall complication rate was 31/116 (26.7%). Parent vessel occlusion, covered branch occlusion, and in-stent stenosis were detected in 9/99 (9.1%), 6/63 (9.5%), and 15/99 (15.2%) cases, respectively. The FRED-related, symptomatic, thromboembolic, and hemorrhagic complication rates were 22.4%, 12.9%, 6.9%, and 0.9% respectively. The morbidity rate was 10/116 patients (8.6%). There was 1 death due to massive periprocedural internal carotid artery stroke, and 3.6% of the patients had an mRS score > 2 at the last follow-up (vs 0.9% at baseline).

CONCLUSIONS
As the first large-scale North American multicenter FRED experience, this study confirmed the ease of successful FRED deployment but suggested lower efficacy and a higher rate of complications than reported by previous European and South American studies on FRED and other flow-diverting devices. The authors recommend judicious use of this device until future studies can better elucidate the long-term outcomes of FRED treatment.
Long-term outcomes after surgery for brainstem cavernous malformations: analysis of 46 consecutive cases
Authors: Hori Tomokatsu , Chernov Mikhail , Alshebib Yasir A. , Kubota Yuichi , Matsuo Seigo , Shiramizu Hideki , Okada Yoshikazu 
Published: September 2022

OBJECTIVE
The objective of this study was to evaluate the long-term outcomes after resection of brainstem cavernous malformations (BSCMs) and to assess the usefulness of the Lawton grading system in these cases.

METHODS
This retrospective study analyzed 46 consecutive patients with BSCMs operated on between July 1990 and December 2020. Outcomes at the last follow-up were defined as favorable (modified Rankin Scale [mRS] score 0–2) or unfavorable (mRS score > 2).

RESULTS
The study cohort comprised 24 men (52%) and 22 women (48%), ranging in age from 8 to 78 years old (median 37 years). In 19 patients (41%), the preoperative mRS score was > 2. All patients had hemorrhagic BSCM. There were 12 (26%) mesencephalic, 19 (41%) pontine, 7 (15%) medullary, and 8 (17%) cerebellar peduncle lesions, with a maximal diameter ranging from 5 to 40 mm (median 15 mm). In total, 24 BSCMs (52%) had bilateral extension crossing the brainstem midline. Lawton grades of 0, I, II, III, IV, V, and VI were defined in 3 (7%), 2 (4%), 10 (22%), 11 (24%), 8 (17%), 7 (15%), and 5 (11%) cases, respectively. Total resection of BSCMs was attained in 43 patients (93%). There were no perioperative deaths. Excluding the 3 most recent cases, the length of follow-up ranged from 56 to 365 months. The majority of patients demonstrated good functional recovery, but regress of the preexisting oculomotor nerve deficit was usually incomplete. No new hemorrhagic events were noted after total resection of BSCMs. In 42 patients (91%), the mRS score at the time of last follow-up was ≤ 2 (favorable outcome), and in 18 (39%), it was 0 (absence of neurological symptoms). Forty-four patients (96%) demonstrated clinical improvement and 2 (4%) had no changes compared with the preoperative period. Multivariate analysis revealed that only lower Lawton grade had a statistically significant independent association (p = 0.0280) with favorable long-term outcome. The area under the receiver operating characteristic curve for prediction of favorable outcome with 7 available Lawton grades of BSCM was 0.93.

CONCLUSIONS
Resection of hemorrhagic BSCMs by an experienced neurosurgeon may be performed safely and effectively, even in severely disabled patients. In the authors’ experience, preexisting oculomotor nerve palsy represents the main cause of permanent postoperative neurological morbidity. The Lawton grading system effectively predicts long-term outcome after surgery.
The Committee on Advanced Subspecialty Training–accredited postgraduate neurosurgery fellowship application experience: a national survey
Authors: Shlobin Nathan A. , Graffeo Christopher S. , Dornbos David L. , Mukherjee Debraj , Sivakumar Walavan , Johnson Jeremiah , _ _ 
Published: September 2022

OBJECTIVE
The neurosurgery fellowship application process is heterogenous. Therefore, the authors conducted a survey of individuals graduating from Committee on Advanced Subspecialty Training (CAST)–accredited fellowships in the past 5 years to examine 1) experiences with the fellowship application process, 2) perspectives on the process, 3) reasons for pursuing a given subspecialty and fellowship, and 4) post-fellowship practices.

METHODS
A survey querying demographics, experiences with and perspectives on the fellowship application process, and factors contributing to the pursuit of a given fellowship was distributed to individuals who had graduated from CAST-accredited fellowships in the past 5 years. The survey response period was May 22, 2021–June 22, 2021.

RESULTS
Of 273 unique individuals who had graduated from CAST-accredited fellowships in the past 5 years, 65 (29.7%) were included in this analysis. The most common postgraduate year (PGY) during which respondents applied for fellowship positions was PGY5 (43.8%), whereas the most common training level at which respondents accepted a fellowship position was PGY6 (46.9%), with a large degree of variability for both (range PGY4–PGY7). Only 43.1% respondents reported an application deadline for their fellowship. A total of 77.4% respondents received 1–2 fellowship position offers, and 13.4% indicated that there was a match process. In total, 64.5% respondents indicated that the fellowship offer timeline was mostly or very asynchronous. The time frame for applicants to decline or accept a fellowship offer was heterogeneous and mismatched among institutions. Respondents agreed that a more standardized application timeline would be beneficial (median response "agree"), and 83.1% of respondents indicated that PGY5 or PGY6 was the appropriate time to interview for a fellowship.

CONCLUSIONS
Respondents reported heterogeneous experiences in applying for a fellowship, indicated that a standardized application timeline including interviews at PGY5 or PGY6 would be beneficial, and preferred streamlining the fellowship application process.
Long-term consequences of residual lesions after chemoradiotherapy in patients with germinoma at onset
Authors: Yamaguchi Shigeru , Okamoto Michinari , Ishi Yukitomo , Sawaya Ryosuke , Motegi Hiroaki , Sugiyama Minako , Harada Taisuke , Fujima Noriyuki , Mori Takashi , Hashimoto Takayuki , Takakuwa Emi , Manabe Atsushi , Kudo Kohsuke , Aoyama Hidefumi , Fujimura Miki 
Published: September 2022

OBJECTIVE
In patients with intracranial germ cell tumors, residual lesions are sometimes observed after completion of primary chemoradiotherapy. Although salvage resection of these end-of-treatment residual lesions is recommended for patients with nongerminomatous germ cell tumors, the necessity of early salvage resection for those with germinoma is not clear. The aim of this study was to investigate the frequency of residual germinoma lesions after primary chemoradiotherapy, as well as their management, long-term consequences, and prognosis.

METHODS
The authors retrospectively reviewed patients who were primarily treated for germinoma between 2002 and 2021. Residual lesions were evaluated with MRI with and without contrast enhancement within 2 weeks after chemoradiotherapy. The decision to perform salvage resection of residual lesions was at the discretion of the treating physicians. The change in appearance of residual lesions was assessed with serial MRI. Overall survival (OS), progression-free survival (PFS), and recurrence pattern were also investigated.

RESULTS
Sixty-nine patients were treated with chemoradiotherapy for germinoma, with a mean follow-up period of 108 months. Residual lesions were radiologically observed in 30 patients (43.5%). Among these, 5 patients (3 with pineal lesions and 2 with basal ganglia lesions) underwent salvage resection. Pathological examination revealed teratomatous components in 3 patients, whereas no tumoral components were identified in 2 patients. One patient with a basal ganglia lesion showed worsening of hemiparesis postoperatively. The remaining 25 patients received watchful observation without surgical intervention. Chronological periodic radiological change in residual lesions was evaluated in 21 patients. One year after primary treatment, the size of the residual lesions was stable and had decreased in 10 and 11 patients, respectively. None of the lesions increased in size. The 10-year PFS and OS rates were 96.7% and 97.3% in patients without residual lesions (n = 39), and 87.1% and 100% in patients with residual lesions (n = 30), respectively. Presence of residual lesions had no significant effect on PFS or OS. All recurrences occurred at distant sites or via dissemination without progression of the primary tumor site, regardless of the presence of residual lesion.

CONCLUSIONS
End-of-treatment residual lesions are not rare in patients with germinoma, and these residual lesions seldom show progression. Because of the potential risk of surgical complications, the indication for early salvage surgery for residual lesions should be carefully determined. Watchful observation is recommended for the majority of these cases.
Proposed Polish Advertisement Levies – An Efficient Source of Public Income or Instruments of the Political Battle?
Authors: Duda-Hyz Michalina 
Published: September 2022

This article analyses the bill of 2nd February 2021 on additional revenues of the National Health Fund, the National Fund for the Protection of Historical Monuments and the establishment of a Fund for the Support of Culture and National Heritage in the Media Area. The draft legislation, the announcement of which has triggered an unprecedented blackout protest in private media as well as a mass anti-government protest on the Internet, provides for the introduction of new public levies called advertisement contributions and the establishment of a new state special-purpose fund – the Fund for the Support of Culture and National Heritage in the Media Area. The aim of the article is to identify and present those provisions of the draft act which have evoked most controversies and have given rise to the stiff social resistance to the proposal. The first part of the paper is devoted to the assessment of the regulations within the context of the objective of the bill that was declared by the drafters in the legislative rationale. The analysis carried out has supported the assumption that providing adequate finances for those special-purpose funds that are strongly involved in remedying the consequences of the SARS CoV-2 epidemic was not a genuine purpose of the bill. It also leads to the conclusion that there is no constitutional justification for such a special-purpose levy. In the second part, the controversies over technical components of the advertising levies have been presented and analysed. On the basis of this analysis, it is possible to conclude that some of the qualitative and quantitative elements of the so-called advertisement contributions may give rise to interpretative doubts. The implementation of the research objectives made it possible to formulate a thesis that the advertisement contributions, as drafted, would not be efficient instruments of fair taxation of digital economy but rather would form instruments for achieving certain political objectives.
Neutron scattering on DIoGENE at IPHI–neutrons
Authors: Darpentigny Jacques , Ott Frédéric 
Published: September 2022

The IPHI–Neutrons facility is a low energy neutron CANS ( E p = 3 MeV) used to test various technologies for the construction of high current CANS (HiCANS). Part of the research program includes the investigation of the possibility to perform neutron scattering and radiography experiments around CANS. For this purpose, the DIoGENE instrument has recently been installed around the IPHI source. The instrument is aimed as a general-purpose neutron scattering instrument featuring 256 high-pressure 3 He tubes covering a solid angle of 0.74 sr. The instrument is especially suited for diffraction experiments but may be upgraded as a SANS or reflectometry instrument. We are using the DIoGENE instrument to investigate the performances of the neutron TMR, the issues related to background noise due to fast neutrons and gamma rays productions and more generally the ToF data acquisition protocols and processing in event mode. We present in this communication the recent diffraction results obtained on DIoGENE during the tests of the new high power Be target on IPHI–Neutrons.
A fast classification method of mass data in Internet of things based on fuzzy clustering maximum tree algorithm
Authors: Duan Zhixia , Tang Shuai 
Published: September 2022

In order to improve the classification accuracy and shorten the classification time of mass data, a fast classification method of mass data in the Internet of things based on fuzzy clustering maximum tree algorithm is proposed. Reduce the dimension to process the mass data of the Internet of things, establish the time series of the mass data of the Internet of things, and complete the preprocessing of the mass data of the Internet of things. Extract the feature vector of the Internet of things mass data, and use the fuzzy clustering maximum tree algorithm to perform fuzzy clustering analysis on the Internet of things mass data, so as to realize the classification of the Internet of things mass data. The results show that the recall rate of the proposed method is as high as 97.5%, the root mean square error is only 0.030, and the classification time is only 12.3 ms.
Upaya Meningkatkan Penguasaan Konsep IPA melalui Penggunaan Media Audio Visual
Authors: Iskandar Joni Iskandar 
Published: September 2022

Pembelajaran jarak jauh yang dilaksanakan selama pandemi di SMPN 1 Bandar Lampung secara daring (dalam jaringan) dengan dua kegiatan yaitu sinkronous dengan aplikasi Zoom Meeting dan asinkronus dengan aplikasi Google Classroom. Berdasarkan pengamatan terhadap PJJ dalam jaringan yang telah dilakukan terlihat bahwa motivasi belajar mandiri peserta didik masih rendah. Hal tersebut juga sejalan dengan hasil belajar siswa secara rata-rata masih dibawah kriteria ketuntasan minimal (KKM). Selama pelaksanaan PJJ daring, ternyata guru kurang mengoptimalkan penggunaan media pembelajaran dan kurang menggali penguasaan konsep siswa. Sebagai upaya pemecahan terhadap masalah yang timbul maka perlu dilakukan Penelitian Tindakan Kelas (PTK). Tujuan dari penelitian ini adalah untuk meningkatkan penguasaan konsep IPA peserta didik pada materi Listrik Dinamis dengan menerapkan pembelajaran menggunakan media Audio Visual. Penelitian ini dilakukan di SMPN 1 Bandar Lampung dengan melibatkan 30 peserta didik kelas IX.9 semester ganjil tahun pelajaran 2020/2021. Penelitian ini dilakukan dalam 2 siklus kegiatan, dimana setiap siklus terdiri dari dua pertemuan. Tahapan kegiatan yang dilakukan pada tiap-tiap siklus meliputi perencanaan, pelaksanaan tindakan, evaluasi dan refleksi. Hasil penelitian ini menunjukkan bahwa terdapat kenaikan pada aktivitas dan penguasaan konsep peserta didik, dimana pada siklus I aktivitas siswa rata-ratanya 72,16 dan pada siklus II 87,5 sedangkan penguasaan konsep peserta didik nilai rata-rata pada siklus I 73,05 dan pada siklus II nilai rata-ratanya 85.
Pengaruh Metode Demonstrasi disertai Video Animasi Terhadap Hasil Belajar IPA Siswa Kelas VIII SMPN 6 Kerinci
Authors: Angela Lia 
Published: September 2022

Penelitian ini bertujuan untuk mengetahui pengaruh metode demonstrasi disertai video animasi terhadap hasil belajar IPA siswa kelas VIII SMPN 6 Kerinci. Metode yang digunakan dlaam peneltiian ini yaitu peneltiian Quasi Eksperimen. Sampel penelitian ini yaitu siswa kelas VIII A sebagai kelas kontrol dan siswa kelas VIII C sebagai kelas eksperimen. Teknik pengumpulan data yaitu menggunakan post-test dengan rancangan non equivalent post-test only control group design. Teknik analisis data menggunakan uji-t. Hasil analisis data diperoleh bahwa rata-rata hasil belajr siswa di kelas eksperimen yaitu 78,18 dan kelas kontrol 64,79. Hasil uji hipotesis diperoleh thitung=6,3459 dan ttabel=2,0137 dengan arti thitung> ttabel sehingg H0 ditolak dan H1 diterima, jadi dapat disimpulkan metode demonstrasi disertai video animasi berpenagruh terhadap hasil belajar.
PENGEMBANGAN BANK SOAL DALAM UPAYA PENINGKATAN PROFESIONALISME GURU PAI PADA MASA PANDEMI DI SMP KEMALA BHAYANGKARI 1 SURABAYA
Authors: Hanifah Dinda Salsabila Amadea , Muthmainnah Iin , Muslim Imam , Mukaffa Zumrotul 
Published: September 2022

Bank Soal adalah bentuk nyata dari profesionalisme guru terutama dimasa pandemi yang berlansung dimana dunia pendidikan harus sigap dan adaptif terhadap berbagai keadaan. Pengabdian masyarakat ini bertujuan untuk merumuskan dan menyusun Bank Soal yang berkualitas dan adaptif dimasa pandemi. Metode dalam pengabdian ini adalah Community Based Research. Pengembangan Bank Soal ini dilaksanakan di SMP Kemala Bhayangkari 1 Surabaya. Kegiatan dilaksanakan dengan antusias dan kooperatif. Hasil dari pengembangan Bank Soal bisa diterapkan dengan baik dan mempunyai manfaat yang berkepanjangan Kata kunci: Bank Soal, profesionalisme, guru, evaluasi.
PENDAMPINGAN BELAJAR ANAK-ANAK MEMBACA AL–QUR’AN DENGAN ILMU TAJWID DI DESA RATU JAYA KABUPATEN LAMPUNG UTARA
Authors: Muhammad Hasanuddin , Al Mu'min Yudha Tama 
Published: September 2022

Masjid Nurul Sholah merupakan sebuah masjid yang berada di Desa Ratu Jaya Kabupaten Lampung Utara dan dijadikan sebagai tempat mengaji bagi mereka yang ingin belajar mengaji. Namun, terdapat masalah yang masih menjadi persoalan dalam membacanya yaitu masih kurangnya menerapkan ilmu tajwid yang benar. Anak – anak yang mengaji hanya menerapkan pelafalan huruh hijaiyah tanpa menerapkan ilmu tajwidyang benar. Tujuan dari kegiatan ini adalah untuk memberikan pembelajaran kepada anak – anak yang mengaji agar bacaannya sudah sesuai dengan ilmutajwid. Metode yang digunakan dalam pendampingan adalah dengan tatap muka mengajar mengaji kepada anak – anak yang mengaji di masjid Nurul Sholah. Hasil pengabdian ada peningkatan kemampuan membaca al-qur’an dengan tajwid.
PENGARUH KONSEP DIRI DAN DUKUNGAN SOSIAL TEMAN SEBAYA TERHADAP PRESTASI BELAJAR MATEMATIKA SISWA KELAS VIII SMPN 1 SALOMEKKO
Authors: Fitriani Fitriani 
Published: September 2022

Penelitian ini bertujuan untuk mengetahui konsep diri siswa kelas VIII SMPN 1 Salomekko, untuk mengetahui dukungan sosial teman sebaya siswa kelas VIII SMPN 1 Salomekko, untuk mengetahui prestasi belajar matematika siswa kelas VIII SMPN 1 Salomekko,untuk mengetahui ada tidaknya pengaruh konsep diri terhadap prestasi belajar matematika siswa kelas VIII SMPN 1 Salomekko, untuk mengetahu ada tidaknya pengaruh dukungan sosial teman sebaya terhadap prestasi belajar matematika siswa SMPN 1 Salomekko, dan untuk mengetahui ada tidaknya pengaruh konsep diri dan dukungan sosial teman sebaya terhadap prestasi belajar matematika siswa kelas VIII SMPN 1 Salomekko.Penelitian ini merupakan penelitian kuantitatif jenis korelasi yaitu korelasi sebab akibat. Populasi dalam penelitian ini adalah seluruh siswa kelas VIII SMPN 1 Salomekko tahun ajaran 2013/2014 yang berjumlah 204 siswa. Sampel diambil dengan menggunakan teknik Simple Random Sampling yaitu berjumlah 51 siswa. Teknik pengumpulan data yaitu dengan menggunakan instrumen skala dan dokumentasi. Teknik analisis data menggunakan analisis statistik deskriptif dan analisis statistik inferensial. Berdasarkan hasil analisis statistik deskriptif diperoleh rata-rata konsep diri siswa sebesar 58,882 berada pada kategori sedang. Rata-rata dukungan sosial teman sebaya sebesar 103,9608 berada pada kategori sedang. Rata-rata prestasi belajar matematika siswa sebesar 76,3137 berada pada kategori sedang. Berdasarkan hasil pengujian statistik diperoleh persamaan regresi 47,103 + 0,382 + 0,061 . Adapun uji hipotesis menunjukkan F0>Ftabel . Dengan demikian dapat disimpulkan bahwa ada pengaruh konsep diri dan dukungan sosial teman sebaya terhadap prestasi belajar matematika siswa kelas VIII SMPN 1 Salomekko Kecamatan Salomekko Kabupaten Bone sebesar 16,3%.
Identification of Chemical Compounds in Ziziphus mauritiana Fruit Juice by GC-MS and LC-MS/MS Analysis
Authors: Soraya Syafira , Sukara Endang , Sinaga Ernawati 
Published: September 2022

Ziziphus mauritiana is an edible fruiting plant commonly found in Asia. In Indonesia, this plant grows wild and thrives on the islands of Bali, Lombok, and Sumbawa. Although it is edible and has good potential as food and medicinal ingredient, in Indonesia, the fruits of Z. mauritiana are underutilized and have almost no economic value. Information about the bioactivity and chemical content of the fruit is limited. To evaluate its possibility of being developed as functional food, a GC-MS and LC-MS/MS analysis was carried out to identify the phytochemical content of the fruit juice. From the GC-MS chromatogram, four compounds were identified with a quality match of 85% and above. The compounds were 5-( hydroxymethyl)-2–furancarboxaldehyde (43.45%), 5, 5'-(oxybis(methylene)) bis-2- furancarbox-aldehyde (25.99%), 2,3–dihydro-3,5–dihydroxy–6–methyl-4H–pyran–4-one (6.05%), and hexadecanoic acid (2.16%). The result of the LC-MS/MS analysis showed 42 peaks of different chemical compounds and included several groups of compounds such as flavonoids, alkaloids, phenols, terpenoids, and organic acids. From these results, it can be concluded that Ziziphus mauritiana fruit juice contains various chemical compounds that are likely to have medicinal activity and therefore has good potential to be used and developed as a functional food.