bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between Fuchs Endothelial Corneal Dystrophy, Diabetes Mellitus and Multimorbidity
Authors: Nealon Cari L. , Halladay Christopher W. , Gorman Bryan R. , Simpson Piana , Roncone David P. , Canania Rachael L. , Anthony Scott A. , Sawicki Rogers Lea R. , Leber Jenna N. , Dougherty Jacquelyn M. , Bailey Jessica N. Cooke , Crawford Dana C. , Sullivan Jack M. , Galor Anat , Wu Wen-Chih , Greenberg Paul B. ,   the Million Veteran Program, Lass Jonathan H. , Iyengar Sudha K. , Peachey Neal S. 
Published: December 2022

AbstractPurposeTo assess risk for demographic variables and other health conditions that are associated with Fuchs endothelial corneal dystrophy (FECD).MethodsWe developed a FECD case-control algorithm based on structured EHR data and accuracy confirmed by individual review of charts at three VA Medical Centers. This algorithm was applied to the Department of Veterans Affairs Million Veteran Program cohort from whom sex, genetic ancestry, comorbidities, diagnostic phecodes and laboratory values were extracted. Single and multiple variable logistic regression models were used to determine the association of these risk factors with FECD diagnosis.ResultsBeing a FECD case was associated with female sex, European genetic ancestry, and a greater number of comorbidities. Of 1417 diagnostic phecodes evaluated, 213 had a significant association with FECD, falling in both ocular and non-ocular conditions, including diabetes mellitus (DM). Five of 69 laboratory values were associated with FECD, with the direction of change for four being consistent with DM. Insulin dependency and type 1 DM raised risk to a greater degree than type 2 DM, like other microvascular diabetic complications.ConclusionsFemale gender, European ancestry and multimorbidity increased FECD risk. Endocrine/metabolic clinic encounter codes as well as altered patterns of laboratory values support DM increasing FECD risk. Our results evoke a threshold model in which the FECD phenotype is intensified by DM and potentially other health conditions that alter corneal physiology. DM may modify FECD onset and encourage progression among susceptible individuals, suggesting that optimizing glucose control may be an effective preventative for FECD.
COVID-19db linkage maps of cell surface proteins and transcription factors in immune cells
Authors: Ramjattun Koushul , Ma Xiaojun , Gao Shou-Jiang , Singh Harinder , Osmanbeyoglu Hatice Ulku 
Published: December 2022

ABSTRACTThe highly contagious SARS-CoV-2 and its associated disease (COVID-19) are a threat to global public health and economies. To develop effective treatments for COVID-19, we must understand the host cell types, cell states and regulators associated with infection and pathogenesis such as dysregulated transcription factors (TFs) and surface proteins, including signaling receptors. To link cell surface proteins with TFs, we recently developed SPaRTAN (Single-cell Proteomic and RNA-based Transcription factor Activity Network) by integrating parallel single-cell proteomic and transcriptomic data based on Cellular Indexing of Transcriptomes and Epitopes by sequencing (CITE-seq), which contains gene cis-regulatory information. We apply SPaRTAN to CITE-seq datasets from patients with varying degrees of COVID-19 severity and healthy controls to identify the associations between surface proteins and TFs in host immune cells. Here, we present COVID-19db of Immune Cell States (https://covid19db.streamlit.app/), a web server containing cell surface protein expression, SPaRTAN-inferred TF activities, and their associations with major host immune cell types. The data include four high-quality COVID-19 CITE-seq datasets with a toolset for user-friendly data analysis and visualization. We provide interactive surface protein and TF visualizations across major immune cell types for each dataset, allowing comparison between various patient severity groups for the discovery of potential therapeutic targets and diagnostic biomarkers.
Pursuing alignment of clients' and contractors' perceptions of client satisfaction in Saudi Arabian projects
Authors: Alshihre Fawaz , Chinyio Ezekiel , Nzekwe-Excel Chinny , Daniel Emmanuel I. 
Published: December 2022

PurposeThe study explored the disparity between construction clients and contractors on what constitutes “client satisfaction”. Such disparity is important because it can lead to different conclusions and thus disagreement on the assessment of project success.Design/methodology/approachThe philosophical stance was interpretivism, thus the qualitative methodology was adopted. Employing purposive sampling, 30 interviews with clients and another 30 interviews with contractors were conducted in Saudi Arabia. The data obtained were evaluated by thematic analysis.FindingsThe results indicate differences in the consensus ad idem (meeting of the minds) between clients and contractors in terms of both their perceptions and prioritisation of the attributes that underpin client satisfaction. For example, some contractors thought that using advanced technologies was very important for client satisfaction, whereas some clients preferred the contractors to be honest with them.Research limitations/implicationsThe data collection was limited to Saudi Arabia and only the views of clients and contractors were studied, thereby limiting the generalisability of the findings.Practical implicationsThe identification of the differing priorities of clients and contractors on client satisfaction provides an informed basis to make more concerted efforts to satisfy clients and minimise disputes on projects in Saudi Arabia.Originality/valueThe study contrasted the views of clients and contractors simultaneously on the subject matter of client satisfaction in relation to project success, and analysed this through the lens of consensus ad idem. The key influences on clients' satisfaction in Saudi Arabia are also presented.
Uncovering the antecedents and motivational determinants of job crafting
Authors: Masood Huda , Podolsky Mark , Budworth Marie-Helene , Karajovic Stefan 
Published: December 2022

PurposeThe purpose of this mixed-methods study is to examine the motivational determinants and contextual antecedents of individual job crafting behaviors.Design/methodology/approachThe current research uses the mixed-methods design to elucidate the relationship between career outcome expectations and different forms of job crafting through external regulation. In Study 1, surveys were collected and analyzed from 151 employees across occupations and ranks using purposeful sampling approach. In Study 2, interview data were thematically analyzed to add complementarity and completeness to the findings.FindingsIn Study 1 (n = 151), a direct relationship between career outcome expectations and different forms of job crafting was established. Mediation analysis indicated an indirect relationship between career outcome expectations and approach crafting through external-social regulation. The authors found support for the accentuating role of turnover intentions on career outcome expectations and external social and material regulations. In Study 2 (n = 25), a thematic analysis of semi-structured interviews confirmed that when employees experience unfulfilled career expectations, employees attempt to realign the work situations. Such expectations may be tied to various forms of work-related external regulations and may lead to job crafting behaviors. The individuals depicted these behaviors while experiencing turnover intentions.Originality/valueThe current study brings together literature from job design, motivation and careers to consider the role of career expectations and external regulation in predicting job crafting behaviors. Taken together, the findings unearth the cognitive and contextual antecedents of job crafting.
Intersectoral approaches: the key to mitigating psychosocial and health consequences of disasters and systemic risks
Authors: Gousse-Lessard Anne-Sophie , Gachon Philippe , Lessard Lily , Vermeulen Valérie , Boivin Maxime , Maltais Danielle , Landaverde Elsa , Généreux Mélissa , Motulsky Bernard , Le Beller Julien 
Published: December 2022

PurposeThe current pandemic and ongoing climate risks highlight the limited capacity of various systems, including health and social ones, to respond to population-scale and long-term threats. Practices to reduce the impacts on the health and well-being of populations must evolve from a reactive mode to preventive, proactive and concerted actions beginning at individual and community levels. Experiences and lessons learned from the pandemic will help to better prevent and reduce the psychosocial impacts of floods, or other hydroclimatic risks, in a climate change context.Design/methodology/approachThe present paper first describes the complexity and the challenges associated with climate change and systemic risks. It also presents some systemic frameworks of mental health determinants, and provides an overview of the different types of psychosocial impacts of disasters. Through various Quebec case studies and using lessons learned from past and recent flood-related events, recommendations are made on how to better integrate individual and community factors in disaster response.FindingsResults highlight the fact that people who have been affected by the events are significantly more likely to have mental health problems than those not exposed to flooding. They further demonstrate the adverse and long-term effects of floods on psychological health, notably stemming from indirect stressors at the community and institutional levels. Different strategies are proposed from individual-centered to systemic approaches, in putting forward the advantages from intersectoral and multirisk researches and interventions.Originality/valueThe establishment of an intersectoral flood network, namely the InterSectoral Flood Network of Québec (RIISQ), is presented as an interesting avenue to foster interdisciplinary collaboration and a systemic view of flood risks. Intersectoral work is proving to be a major issue in the management of systemic risks, and should concern communities, health and mental health professionals, and the various levels of governance. As climate change is called upon to lead to more and more systemic risks, close collaboration between all the areas concerned with the management of the factors of vulnerability and exposure of populations will be necessary to respond effectively to damages and impacts (direct and indirect) linked to new meteorological and compound hazards. This means as well to better integrate the communication managers into the risk management team.
Penetrating or expanding: the dilemma at Raushangul atelier studio, Kazakhstan
Authors: Mirzaliyeva Sanam Sunnatullayevna , Chakraborty Kamalika , Biswas Samir , Berikkyzy Dina , Tleubek Dina 
Published: December 2022

Learning outcomes
After the case discussion in class, the audience is expected to:▪ Apply the use of management tools in identifying core competencies in the sustenance and growth of a venture.▪ Evaluate the sustainability of the core competencies using relevant tools and frameworks.▪ Assess using relevant criteria whether firms should diversify or not?

Case overview/synopsis
The case highlights the experience and obstacles encountered by a Kazakh entrepreneur, Moldakhmetova, who is exploring her long-term business continuity choices. Moldakhmetova ran her own tailoring business, which focused mostly on designing and creating national costumes worn at weddings and concerts. However, she was confronted with a number of obstacles pertaining to the long-term viability of her enterprise, especially with the commencement of the Covid pandemic. The volume of national costume sales was affected by the declaration of the lockdown and restrictions on concerts and celebrations. As the lockdown lifted and orders started to pour in, Moldakhmetova pondered the long-term viability of her business venture. In addition, the availability of inexpensive ready-made Moldakhemetova costumes in Almaty (one of the major cities) made her question whether or not they were her competitors. Thus, Atlas contemplated many choices as potential answers to the question of the enterprise's long-term viability. She was currently faced with the dilemma of selecting the most feasible solution from the possibilities she had identified.

Complexity academic level
BBA and MBA programs.

Supplementary materials
Teaching notes are available for educators only. Students are recommended to watch the video about the Kazakh folk style of clothing at: https://www.youtube.com/watch?v=ddVzrUeSn64 (25 minutes). Students can watch the following video about specific embroidery styles applied in Kazakh national clothing at: https://www.youtube.com/watch?v=wB0XJE09N9w (first 10 minutes of video). The case could be used in online teaching via the Padlet platform.

Subject Code
CSS: 11: Strategy.
Beardo’s strategic partnership with Marico
Authors: Saxena Meetali , Mahajan Harleen 
Published: December 2022

Learning outcomes
• The students will be able to compare various perspectives and concepts of strategic alliance as a tool of corporate expansion.
• The students will be able to identify the trade-offs between financial and non-financial gains and losses for corporate expansion.
• The students will be able to identify strategic partnership as a better alternative in comparison to acquisition and vice versa according to the different situations being faced by the companies.
• The students will be able to identify different approaches for brand building.

Case overview/synopsis
Shah and Valani, owners of Zed Lifestyle Pvt Ltd which owned Beardo, had to decide whether they should accept the offer of a strategic partnership with Marico Industries, a fast-moving consumer goods company (FMCG) in the global beauty and wellness space. Marico nurtured leading brands across categories of hair care, skin care, edible oils, healthy foods, hygiene, male grooming and fabric care. The decision was not easy as Marico was a leader in the FMCG segment in India and had a strong brand presence in both online and offline distribution channels. Beardo, on the other hand, had its presence marked mostly on the online channel with a hundred offline salon outlets. Partnering with Marico would ensure access to the massive distribution channel owned by Marico but, on the other hand, would lead to possible loss of independence and an early exit from their business. They were not prepared to let go of their ownership as there was no clarity on what would happen if the projected growth figures were not met. There were many other questions too that crossed their minds which had to be answered before they decided on a yes or a no.
The case highlighted the decision dilemma faced by the brand owners, the market scenario, competitive landscape and the situational facts so as to help the students critically analyse the decision situation and develop decision-making competencies by evaluating the possible course of actions and their possible outcomes.

Complexity academic level
Corporate-level strategies.

Supplementary materials
Teaching notes are available for educators only.

Subject code
CSS 11: Strategy.
The roles of experience and gender in shaping work values
Authors: Waterwall Brian , Chullen Cody Logan , Barber Dennis , Adeyemi-Bello Tope 
Published: December 2022

PurposeThis paper aims to examine work values among job seekers and how these values differ across experience and gender.Design/methodology/approachThis study asked participants to rate the importance of various intrinsic and extrinsic work values on a five-point Likert scale. Responses were compared for 865 participants.FindingsThis study found that individuals differed in their ratings of work values based on experience. Individuals with more experience assigned greater importance to intrinsic job characteristics, while those with less experience assigned greater importance to extrinsic job characteristics. Findings further reveal differences in gender ratings of work values, with females assigning greater importance ratings to both intrinsic and extrinsic job characteristics as compared to males.Research limitations/implicationsLimitations of this study include that it drew its data exclusively from a sample of US respondents. Research investigating populations from other geographic regions within the same study may uncover important cross-national similarities/differences. Moreover, although this study examined experience and gender, it excluded other potentially important factors such as ethnicity. Future research should explore international samples and broaden its focus to include additional factors.Practical implicationsOrganizations should be aware of how experience and gender shape work values to impact job choice and retention. They may wish to target their recruitment efforts toward certain groups to ensure alignment between candidates' work values and those of available positions.Originality/valueThis study improves on prior research by examining the dual impact of experience and gender in shaping work values.
Post-pandemic revisit intentions: how shopping value and visit frequency matters
Authors: Moharana Tapas Ranjan , Pattanaik Subidita 
Published: December 2022

PurposeThis paper examines the effect of shopping value (utilitarian, hedonic and social) on shopping satisfaction and store revisit intention in the post-pandemic phase. Additionally, the authors investigate how shoppers’ COVID-responsible behaviour and visit frequency are contingent on their shopping value evaluations.Design/methodology/approachData were collected (n = 527) using the store intercept method during March 2022 (a recovery phase from the third wave of COVID-19 in India). The authors adopted structural equation modelling to test the proposed model.FindingsShopping values significantly impacted shopping satisfaction and store revisit intentions. The effects of utilitarian and hedonic value on satisfaction were stronger for frequent shoppers than infrequent shoppers. While utilitarian value contributes to stronger satisfaction of COVID-responsible shoppers, COVID-non-responsible shoppers are better satisfied with social value. The impact of hedonic and social value on satisfaction has reduced significantly from the pre- to post-pandemic phase.Practical implicationsPractising managers should recognise that positive shopping value evaluations are important for generating satisfaction. Notably, the utilitarian value becomes more important in times of environmental exigencies. The study provides insights to devise strategies to attract and retain frequent shoppers who are major contributors to the store’s profit.Originality/valueThis study is one of the few studies which focuses on in-store shopping and consumers’ shopping value evaluations in a COVID-19 recovery phase. This study is one of the first that compares the post-pandemic shopping value judgement to a pre-pandemic phase. The authors provide valuable insights into store revisit intentions of shoppers who behave responsibly in a challenging environment.
Remarkable lives – Ella Vadasz in conversation with Robert Hurst
Authors: Vadasz Ella , Hurst Robert 
Published: December 2022

PurposeThe purpose of this paper is to share Ella Vadasz’s story.Design/methodology/approachElla wrote a biography of her experiences, including two poems. Robert then asked a series of questions from the perspective of a mental health academic.FindingsElla shared stories from her life and how her experiences have shaped her. She talked about the emotional impact of a custody battle.Research limitations/implicationsRecovery narratives such as this give us an overview of only a single person’s experiences. However, they allow the person with lived experiences to explore their story in depth.Practical implicationsWhat Ella has written is very emotional. Her story will give readers an insight into her life and experiences.Social implicationsThere is so much to learn from stories such as Ella’s, in particular from her critique of social services in Scotland and England.Originality/valueTo the best of the authors’ knowledge, this is the first time that Ella has chosen to share her unique story. This paper features two poems written by her – a first for Remarkable Lives. The value of Ella sharing her story is apparent upon reading it.
Adaptive genetic traits in pelagic freshwater microbes
Authors: Chiriac Maria‐Cecilia , Haber Markus , Salcher Michaela M. 
Published: December 2022

AbstractPelagic microbes have adopted distinct strategies to inhabit the pelagial of lakes and oceans and can be broadly categorized in two groups: free‐living, specialized oligotrophs and patch‐associated generalists or copiotrophs. In this review, we aim to identify genomic traits that enable pelagic freshwater microbes to thrive in their habitat. To do so, we discuss the main genetic differences of pelagic marine and freshwater microbes that are both dominated by specialized oligotrophs and the difference to freshwater sediment microbes, where copiotrophs are more prevalent. We phylogenomically analysed a collection of >7700 metagenome‐assembled genomes, classified habitat preferences on different taxonomic levels, and compared the metabolic traits of pelagic freshwater, marine, and freshwater sediment microbes. Metabolic differences are mainly associated with transport functions, environmental information processing, components of the electron transport chain, osmoregulation and the isoelectric point of proteins. Several lineages with known habitat transitions (Nitrososphaeria, SAR11, Methylophilaceae, Synechococcales, Flavobacteriaceae, Planctomycetota) and the underlying mechanisms in this process are discussed in this review. Additionally, the distribution, ecology and genomic make‐up of the most abundant freshwater prokaryotes are described in details in separate chapters for Actinobacteriota, Bacteroidota, Burkholderiales, Verrucomicrobiota, Chloroflexota, and ‘Ca. Patescibacteria’.
The 21st century trust and leadership problem: Quoi faire?
Authors: Anheier Helmut K. , Knudsen Edward L. 
Published: December 2022

AbstractMuch of the democratic world faces a form of socio‐political crisis. To varying degrees, four trends seem to be present in almost every case: declining institutional trust, failing leadership, increasing political polarisation, and weakened accountability. Although each trend has its own dynamic and causes, they jointly create complex challenges and governance problems for democratic societies. Furthermore, underlying them all is the persistent problem of inequality, which erodes trust, prevents the best leaders from rising to the top, polarises society, and shields elites from accountability. We propose a wide range of potential solutions to this crisis. Of the four, we propose that countries focus primarily on increasing institutional trust and improving leadership potential. Both aspects are particularly impactful and malleable, could influence the other two components and, over time, create a virtuous cycle pulling countries out of crisis. Proposed measures for institutional trust include expanded civic literacy, more expansive regulation of tech platforms, stricter media laws to foster better public discourse and a wider use of codes of conduct. For leadership, we propose more diverse channels and expanded selection pools for leadership recruitment, emphasising ethical conviction and targeted incentives for leadership roles. Essential to all of them, however, is tackling inequality.