bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of WFH on educators' wellbeing: mediating role of institutional head's support and moderating role of employees' self-efficacy at university level
Authors: Khan Najmonnisa , Aslam Rabia , Asad Muhammad Mujtaba , Oad Lubna , Almusharraf Norah Mansour 
Published: July 2022

PurposeThe present study aims to examine the effects of work from home (WFH) on employees' performance and wellbeing during the second wave of pandemic and to find out the effects of institutional head's support as mediating variables and employees' self-efficacy as moderating variables on employees' performance and wellbeing during WFH.Design/methodology/approachA quantitative approach with causal comparative research design was adopted to collect the data from the respondents. The participants of the study were 586 teachers from public and private universities of Karachi, Pakistan, who were teaching from home during the second wave of pandemic, selected randomly from the population. An adopted questionnaire was used to collect data which consists of six parts.FindingsResults found the positive significant effects of WFH on teachers' social wellbeing, negative significant effects on teachers' performance, their physical and mental wellbeing. No significant effects of WFH were found on teachers' financial wellbeing. The study also found that head's support plays a partially mediating significant role in the relationship between WFH and job performance, and social wellbeing, while no mediation on physical, social and financial wellbeing was found. Moderating effects of teachers' self-efficacy exist between the relationship of WFH and teachers' job performance, mental wellbeing and social wellbeing, while no effects exist between the relationship of WFH and teachers' physical and financial wellbeing.Originality/valueThe new research model will contribute significantly to education practitioners' knowledge, especially the government of Pakistan, which needs to measure their work from home policy's effectiveness during the pandemic.
An approach based on process mining to assess the quarantine strategies' effect in reducing the COVID-19 spread
Authors: Yari Eili Mansoureh , Rezaeenour Jalal 
Published: July 2022

PurposeThe feasibility of process mining combined with simulation techniques in estimating the effectiveness of COVID-19 prevention strategies on infection and mortality trends to determine best practices is assessed in this study. The quarantine event log is built from the CUSP (the COVID-19 US State Policy) database, where the dates of implemented social policies in the USA to respond to the COVID-19 pandemic are documented.Design/methodology/approachCOVID-19 is a highly infectious disease leading to a very high death toll worldwide. In most countries, the governments have resorted to a series of drastic strategies to prevent the outbreak by restricting the activities and movement among their population for a predefined time. Heretofore, different approaches have been published to estimate quarantine strategies and the majority signify the positive effect on managing this pandemic. Notably, the process perspective of COVID-19 datasets is of less concern among researchers. The purpose of this paper is to exploit the process mining techniques to model and analyze the quarantine implementation processes.FindingsThe discovered process model has 51 process variants for 51 cases (states), which indicate the quarantine activities were executed in different orders and periods during the pandemic. The time interval analysis between activities reveals the states with the most extended quarantine periods. These primary process mining insights are applied to define scenarios and variables of an agent-based model. The simulation findings indicate a meaningful relation between enforcing quarantine strategies and a declining trend of infection by 90% in the case of following strict quarantine and mask mandates. It is observed that in the post-quarantine period, the disease repeats its ascending trend unless implementation of different intervention strategies likes vaccination.Originality/valueThis study is the first in introducing process mining techniques in analyzing the COVID-19 quarantine strategies impact. The findings provide valuable insights for policymakers to proper control strategies and the process mining research community in expanding more process-related analysis on this pandemic. Also, the results have broad implications for research in other fields like information science to estimate the impact of quarantine strategies on process patterns in library systems.
Does repurchase timing matter in promotional framing effect?
Authors: Wang Bo 
Published: July 2022

PurposeAlthough the evidence exists for the effect of promotional frame on repurchase intention, it is unclear whether the timing of repurchase can moderate the effect. In this paper, three experiments were conducted to answer this question.Design/methodology/approachIn Experiment 1, a 2 (framing: bundle vs. gift) × 2 (repurchase target: focal vs. supplementary) × 2 (timing: short vs. long) between-subjects design was used. In Experiment 2, an identical design was used except that repurchase target being the within-subjects factor. In Experiment 3, the design was based on that of Experiment 2 and brand was added a between-subjects factor.FindingsExperiment 1 showed that, with a short interval, repurchase intention under gift frame was higher than that under bundle frame. With a long interval, there was no significant difference between the gift and bundle frames. Experiment 2, however, indicated no effects for expensive products. Experiment 3 showed that brand (private versus national brand) moderate the interaction between framing, repurchase target and timing. Particularly, for private brand, no significant comparisons were found; for national brand, repurchase intention for the focal product was significantly higher than for the supplementary product, but only under the conditions of long interval and gift frame (rather than bundle frame).Originality/valueTaken together, findings from the current study contributes to the literature by showing for the first time that repurchase timing can moderate the promotional frame effect (i.e. higher repurchase intention under gift framing relative to bundle framing occurs in the short interval but not long interval) and that brand type can moderate the joint effects of framing, timing and repurchase target (i.e. national brand, rather than private brand, paired with long interval and gift frame results in higher repurchase intention for the focal product). The findings provide marketers with important knowledge in terms of how to adjust a promotional frame depending on when consumers repurchase a product and whether the product has a private or national brand.
Negotiating insider research through reactive collaboration: challenges, issues and failures
Authors: Snellgrove Miriam , Punch Samantha 
Published: July 2022

PurposeThe purpose of this paper is to highlight the ways in which reactive researcher collaboration helps to manage some of the challenges present in insider research.Design/methodology/approachEmploying (auto)biographical reflections from across two different case-studies, the authors explore the ways in which reactive collaboration is enmeshed with issues associated with researching the familiar in a marketized university environment.FindingsThe authors develop the term “reactive collaboration” to explore the ways in which insider research projects have to deal with a range of challenges from within their own research community. Reactive collaboration is as much about insider research solidarity as it is with reacting to anticipated and unanticipated events during the research process (and how inside researchers do and do not deal with them). Reactive collaboration highlights the successes as well as the failures of insider researchers negotiating complex research situations.Originality/valueThe authors show how reactive collaboration occurs in challenging research environments, including the joys, sorrows and failures. The authors argue that the challenges and benefits of insider research can be helpfully crystalised through reactive collaboration.
Ambidexterity and Agile project management: an empirical framework
Authors: Binci Daniele , Cerruti Corrado , Masili Giorgia , Paternoster Cristina 
Published: July 2022

PurposeThe purpose of this study is to explore the agile project management (APM) approach through the contextual ambidextrous lens by overcoming the traditional perspective that separates projects within the opposite planned-exploitation- and emergent-exploration-oriented forms.Design/methodology/approachThis study uses a grounded approach to five different agile-oriented companies for discovering how agile adoption shows both emergent (exploration-oriented) and planned (exploitation-oriented) tensions in a perspective that connects, rather than separates, them.FindingsThis study discovers five main categories, namely, approach, objectives, boundaries, leadership and feedback, that capture the tensions between planned and emergent issues of agile projects. The identified variables interact with different intervening conditions of the APM attributes (i.e. road map, product backlog, team backlog and solution delivery), activating different response actions (“exploitation embedded in exploration” and vice-versa), requiring, as a consequence, the need for contextual ambidexterity.Research limitations/implicationsThis study identifies different implications based on real project contexts, as the importance of a more complete picture of the APM approach, which also considers the combination of planned and emergent aspects of projects and, as consequence, the needs for dual capacities (T-shaped skills) both at project management and team levels.Practical implicationsThis study identifies, in real project contexts, the relevance of integration between the corporate level and the agile project team. This implies the search for constant dialogue, with feedback exchange spread across all levels, also enabled by an integrated leadership approach.Originality/valueThis study highlights agile tensions in a real-world project context by describing how APM connects both explorative and exploitative aspects of change within the same APM initiative, in order to manage such tensions, which differs from previous studies that consider APM in alternation with a linear project management approach as stage-gate.
Does digitalization limit the proliferation of the shadow economy in African countries? An in‐depth panel analysis
Authors: Haruna Emmanuel Umoru , Alhassan Usman 
Published: July 2022

AbstractWe investigate the relationship between digitalization and the shadow economy in 42 African countries using unbalanced panel data from 2003 to 2016. We begin by drawing on modernization theory to hypothesize that digitalization efforts in African economies represent an augmentation of public service delivery as well as a channel through which the size of the continent's informal economic activity might be reduced. We employ the fixed effects estimation technique as its baseline estimator while correcting for potential endogeneity concerns using an instrumental variable two‐stage least squares technique. We show compelling evidence that digitalization is associated with a decrease in the size of the shadow economy in Africa. However, evidence of a larger influence is driven by the availability of telecommunications infrastructure and the expansion of government online services. These findings suggest that policymakers should invest more in digital technology to formalize Africa's hidden economic activity, particularly to fill the post‐COVID‐19 financing gap.
Stakeholder Orientation and Bank Payout Policy: Evidence from US Constituency Statutes
Authors: Chronopoulos Dimitris K. , Yilmaz Muhammed H. , Wilson John O.S. 
Published: July 2022

AbstractWe investigate the impact of stakeholder orientation on bank payout policy. As a quasi‐experimental setting, we exploit the staggered enactment of constituency statutes across US states, which broaden the scope of managerial duties to an extended group of stakeholders. The results of a difference‐in‐differences analysis suggest that bank holding companies (BHCs) incorporated in states enacting constituency statutes experience significant declines in total payouts, which is driven by a decline in share repurchases. This observed decline in share repurchases is stronger for banks with sizeable implicit claims, lower transparency and substantial agency conflicts. These findings remain intact following a myriad of robustness checks and alternative estimation techniques.
The development and implementation of a new hospital performance measure to assess hospital contributions to community health and equity
Authors: Plott Caroline F. , Thornton Rachel L. J. , Punwani Ekta , Dankwa‐Mullan Irene , Karunakaram Hema , Craig Kelly Jean Thomas , Rhee Kyu , Sharfstein Joshua M. 
Published: July 2022

AbstractObjectiveTo develop and implement a measure of how US hospitals contribute to community health with a focus on equity.Data SourcesPrimary data from public comments and hospital surveys and secondary data from the IBM Watson Top 100 Hospitals program collected in the United States in 2020 and 2021.Study DesignA thematic analysis of public comments on the proposed measure was conducted using an iterative grounded approach for theme identification. A cross‐sectional survey of 207 hospitals was conducted to assess self‐attestation to 28 community health best practice standards in the revised measure. An analysis of hospital rankings before and after inclusion of the new measure was performed.Data Collection/Extraction MethodsPublic comment on the proposed measure was collected via an online survey, email, and virtual meetings in 2020. The survey of hospitals was conducted online by IBM in 2021. The analysis of hospital ranking compared the 2020 and 2021 IBM Watson Top 100 Hospitals program results.Principal FindingsMore than 650 discrete comments from 83 stakeholders were received and analyzed during measure development. Key themes identified in thematic analysis included equity, fairness, and community priorities. Hospitals that responded to a cross‐sectional survey reported meeting on average 76% of applicable best practice standards. Least met standards included providing emergent buprenorphine treatment for opioid use disorder (53%), supporting an evidence‐based home visiting program (53%), and establishing a returning citizens employment program (27%). Thirty‐seven hospitals shifted position in the 100 Top Hospital rankings after the inclusion of the new measure.ConclusionsThere is broad interest in measuring hospital contributions to community health with a focus on equity. Many highly ranked hospitals report meeting best practice standards, but significant gaps remain. Improving measurement to incentivize greater hospital contributions to community health and equity is an important priority.
Implications of missingness in self‐reported data for estimating racial and ethnic disparities in Medicaid quality measures
Authors: Yee Kimberly , Hoopes Megan , Giebultowicz Sophia , Elliott Marc N. , McConnell K. John 
Published: July 2022

AbstractObjectiveTo assess the feasibility and implications of imputing race and ethnicity for quality and utilization measurement in Medicaid.Data Sources and Study Setting2017 Oregon Medicaid claims from the Oregon Health Authority and electronic health records (EHR) from OCHIN, a clinical data research network, were used.Study DesignWe cross‐sectionally assessed Hispanic‐White, Black‐White, and Asian‐White disparities in 22 quality and utilization measures, comparing self‐reported race and ethnicity to imputed values from the Bayesian Improved Surname Geocoding (BISG) algorithm.Data CollectionRace and ethnicity were obtained from self‐reported data and imputed using BISG.Principal Findings42.5%/4.9% of claims/EHR were missing self‐reported data; BISG estimates were available for >99% of each and had good concordance (0.87–0.95) with Asian, Black, Hispanic, and White self‐report. All estimated racial and ethnic disparities were statistically similar in self‐reported and imputed EHR‐based measures. However, within claims, BISG estimates and incomplete self‐reported data yielded substantially different disparities in almost half of the measures, with BISG‐based Black‐White disparities generally larger than self‐reported race and ethnicity data.ConclusionsBISG imputation methods are feasible for Medicaid claims data and reduced missingness to <1%. Disparities may be larger than what is estimated using self‐reported data with high rates of missingness.
Anti‐glycoprotein 2 (anti‐GP2) IgA and anti‐neutrophil cytoplasmic antibodies to serine proteinase 3 (PR3‐ANCA): antibodies to predict severe disease, poor survival and cholangiocarcinoma in primary sclerosing cholangitis
Authors: Wunsch Ewa , Norman Gary L. , Milkiewicz Malgorzata , Krawczyk Marcin , Bentow Chelsea , Shums Zakera , Mahler Michael , Lopens Steffi , Reinhold Dirk , Franke Andre , Schramm Christoph , Roggenbuck Dirk , Milkiewicz Piotr 
Published: July 2022

SummaryBackgroundPrimary sclerosing cholangitis (PSC) is associated with progressive liver disease and cholangiocarcinoma. Although risk stratification is crucial for making clinical decisions, it is hindered by a scarcity of proven prognostic markers.AimsTo assess the value of novel anti‐glycoprotein 2 (anti‐GP2) and anti‐neutrophil cytoplasmic antibodies to serine proteinase 3 (PR3‐ANCA) in combination with PSC‐specific clinical and laboratory markers as predictors of quality of life, disease severity, and cholangiocarcinoma in two large, independent cohorts of PSC patientsMethodsDiscovery (338 Polish patients) and validation (178 German patients) cohorts with PSC were evaluated. Anti‐GP2 (isoforms 1/4) was detected by ELISAs and PR3‐ANCA by chemiluminescence immunoassay. Clinical and laboratory data were collected and analysed. The outcome was defined as liver transplantation‐free survival and occurrence of cholangiocarcinoma during follow‐up.ResultsIn the discovery group, anti‐GP21/4 IgA and PR3‐ANCA were associated with liver dysfunction, anti‐GP21/4 IgA with risk scores for PSC and anti‐GP24 IgA with cirrhosis. All cholangiocarcinoma patients were positive for PR3‐ANCA and/or anti‐GP24 IgA. The association between anti‐GP2 IgA and liver biochemistry, risk scores, cirrhosis, impaired survival, and cholangiocarcinoma was confirmed in the validation cohort. Cox proportional‐hazards regression indicated anti‐GP21 IgA as an independent variable of poor outcome in both study cohorts. Analysis of the combined data showed that anti‐GP24 IgA and PR3‐ANCA were independent predictors for cholangiocarcinoma, while anti‐GP21 IgA and PR3‐ANCA were indicators for poor survival.ConclusionsAnti‐GP2 and PR3‐ANCA are prognostic antibodies in PSC as they identify patients at risk of severe disease, poor survival and biliary cancer.
Editorial: serologic antibodies in primary sclerosing cholangitis – a tell‐tale sign of compromised gut‐liver immunity?
Authors: Tornai David , Papp Maria 
Published: July 2022

LINKED CONTENT
This article is linked to Wunschi et al and Wunsch & Milkiewicz papers. To view these articles, visit https://doi.org/10.1111/apt.16153 and https://doi.org/10.1111/apt.16211
Enhanced stimulation of antigen‐specific immune responses against nucleophosmin 1 mutated acute myeloid leukaemia by an anti‐programmed death 1 antibody
Authors: Greiner Jochen , Goetz Marlies , Schuler Patrick J. , Bulach Christiane , Hofmann Susanne , Schrezenmeier Hubert , Dӧhner Harmut , Schneider Vanessa , Guinn Barbara‐ann 
Published: July 2022

SummaryNucleophosmin1 (NPM1) is one of the most commonly mutated genes in AML and is often associated with a favourable prognosis. Immune responses play an increasing role in AML treatment decisions; however, the role of immune checkpoint inhibition is still not clear. To address this, we investigated specific immune responses against NPM1, and three other leukaemia‐associated antigens (LAA), PRAME, Wilms' tumour 1 and RHAMM in AML patients. We investigated T cell responses against leukaemic progenitor/stem cells (LPC/LSC) using colony‐forming immunoassays and flow cytometry. We examined whether immune checkpoint inhibition with the anti‐programmed death 1 antibody increases the immune response against stem cell‐like cells, comparing cells from NPM1 mutated and NPM1 wild‐type AML patients. We found that the anti‐PD‐1 antibody, nivolumab, increases LAA stimulated cytotoxic T lymphocytes and the cytotoxic effect against LPC/LSC. The effect was strongest against NPM1mut cells when the immunogenic epitope was derived from the mutated region of NPM1 and these effects were enhanced through the addition of anti‐PD‐1. The data suggest that patients with NPM1 mutated AML could be treated with the immune checkpoint inhibitor anti‐PD‐1 and that this treatment combined with NPM1‐mutation specific directed immunotherapy could be even more effective for this unique group of patients.
The use of Monte Carlo simulation to evaluate the optical properties of polyester fabric treated with titanium dioxide nanopigments
Authors: Asadi Laleh , Nateri Ali Shams 
Published: July 2022

AbstractThe current study utilises Monte Carlo simulation and Mie scattering theory to estimate the reflectance spectra of fabric coated with titanium dioxide nanopigments of various diameters and concentrations. Image processing was carried out and experimental data were gathered to evaluate the performance of Monte Carlo simulation. The distribution and location of the nanopigments on the surface of fabric were determined using the Monte Carlo method. Reflection of the fabric was calculated based on Monte Carlo simulation with the partitive mixing method and Mie theory. According to the experimental and simulation results, the reflectance of coated samples was increased by increasing the concentration and number of titanium dioxide nanoparticles. There was a good match between the results obtained by Monte Carlo simulation and the experimental results. For coated samples (dTiO2: 500 nm), the root mean square error between measured and predicted reflectance by the Monte Carlo and partitive mixing method and by Monte Carlo and Mie theory was 0.022 and 0.0078, respectively. The results indicate that the performance of the Monte Carlo and Mie method was better than that of the Monte Carlo and partitive mixing method. According to t‐test analysis, there was no statistically significant difference between the experimental data and Monte Carlo simulation.