bluuebunny/crossref_metadata_2025_split huggingface dataset:
“LET ALONE AT MISS UNIVERSE”: SIERA BEARCHELL AS EMBODIMENT OF CULTURAL RESISTANCE OF FEMININITY IN MISS UNIVERSE
Authors: Quamilla Asyifa 
Published: July 2022

<p><em>The existence of plus size contender in Miss Universe has broken down the normalization of slenderness which has been one of manifestations of femininity in American society and its beauty pageant industries. The plus size lens is brought by Siera Bearchell who has been placed on Top 9 in Miss Universe 2016 edition to resist the cultural normalization of slender body size. By using textual analysis, this research focuses on Siera Bearchell’s YouTube videos and news articles related to the plus size contender to investigate the way she embodies the cultural resistance through her personal practices in the Miss Universe pageant. This research shows that Siera Bearchell has failed at embodying the dominant ideology of feminine slender ideal in Miss Universe. However, this failure cannot put Siera Bearchell to cultural obedience to the bodily ideal. This occurs since Siera Bearchell has resisted the cultural normalization by embodying her plus size body as a state for personal space and freedom. Therefore, the symbol of normalization of feminine slender size contradicts her identity as the plus size contender. </em></p>
METHOD FOR PREDICTION OF DURABILITY OF FRICTION LININGS OF TRACTOR BRAKES
Authors: Podryhalo Mykhailo , Kashkanov Andrei , Shein Vitalii , Kasianenko Oleksii , Uzhyk Valerii 
Published: July 2022

The paper presents the results of a research on the creation of a methodology for predicting the durability of friction linings of tractor brake mechanisms at the design stage. Not only an increase in engine power and tractor weight is taken into account, but also the installation of more advanced brake mechanisms. Thanks to the developed method for predicting the durability of the friction linings of tractor brake mechanisms, the use of unified disc brakes is justified.
To solve the problem, the similarity theory was used, in which the most intense loading mode of the tractor brake mechanisms was modeled. As an indicator, the maximum work performed by the brakes until the friction linings are completely worn out was used. The results of estimating the resource of the friction linings of the tractor brake mechanisms under the most intense loading conditions were compared with the results of the calculation under the actual loading conditions.
Penerapan Metode Eksperimen untuk Meningkatkan Prestasi dan Motivasi Belajar Siswa pada Topik Usaha dan Pesawat Sederhana
Authors: Imeske Anggreni , Sholikhan  , Ain Nurul 
Published: July 2022

Metode eksperimen merupan suatu cara penyajian mata pelajaran dimana siswa secara aktif mengalami dan membuktikan sendiri apa yang sedang dipelajarinya. Melalui metode eksperimen siswa secara total dilibatkan dalam melakukan sendiri, membuktikan dan menarik kesimpulan sendiri tentang suatu objek, keadaan atau proses tertentu.Tujuan penelitian ini adalah untuk mengetahui Penerapan Metode EksperimenUntuk Meningkatkan Prestasi Fisika, Motivasi Belajar Siswa Pada Materi Usaha Dan Pesawat Sederhana Kelas VIII SMP Negeri 03 Ampelgading. Penelitian ini dilaksanakan pada ajaran 2020/2021 di SMP Negeri 03 Ampelgading. Metode penelitianan ini adalah siswa kelas VIII C yang terdiri dari 27 siswa, 17 orang siswa laki-laki dan 10 orang siswa perempuan tahun ajaran 2020/2021. Instrument yang di gunakan dalam penelitian ini adalah lembar observasi keterlaksanaan metode eksperimen, tes berupa soal uraian 5 soal. Perbedaaan pada metode eksperimen yaitu pada siklus I 67,85%, sedangkan pada siklus II 94,04%, antara siswa belajar menggunakan metode eksperimen pada tahap pra siklus sebesar 14,81%, kemudian 18,52% dan 77,78% . Motivasi pada tahap siklus I sebesar 68,42%, siklus II 80,24%.

Kata Kunci: Metode Eksperimen, Prestasi Belajar, Motivasi
Study Investigates Deepwater BOP Technology, Reliability
Authors: Carpenter Chris 
Published: July 2022

This article, written by JPT Technology Editor Chris Carpenter, contains highlights of paper IPTC 21430, “Deepwater Subsea BOP Technological and Reliability Advancement,” by Mahesh Picha, SPE, Malik Faisal Abdullah, and Ashutosh Rai, Petronas, et al. The paper has not been peer reviewed. Copyright 2021 International Petroleum Technology Conference. Reproduced by permission.
Subsea blowout preventer (SBOP) reliability is a major challenge in deepwater drilling and completion operations, accounting for a large portion of major equipment failures and nonproductive time (NPT) costs annually. The complete paper focuses on SBOP technological advancement since the Macondo incident in 2010, with emphasis on reliability, equipment-condition monitoring, and statistical root-cause analysis. The development of new technologies has targeted overall cost optimization of the well life cycle but also has been aimed at assuring SBOP functionality.

Introduction
Drilling contractors are required to establish minimum standards of redundancy and reliability of their SBOP systems and are required to implement an auditable risk-management process to ensure that their SBOP systems operate above minimum standards. A 2015 study found that 38% of NPT events were related to SBOP issues. Of this 38%, 56% were associated with maintenance, 22% with manufacturing issues, 16% with not following operational procedures, and 6% with training time. Because maintenance-related NPT was the major contributor, a detailed analysis was performed and found that frequency of the maintenance cycle, insufficient detailing of maintenance procedures, a lack of specific tools, insufficient spare parts onboard, and unavailability of technical documentation were responsible.
Complement Factor I Deficiency, a study on prevalence and impacts on complement dysregulation and health.
Authors: Kelly Lauren , DeDent Andrea , Patterson Aneeka Hancock , Selters Linday , Lovejoy Christopher , Sowers Rebeka , Holten-Andersen Lars , Frazer-Abel Ashley , Moan Natacha Le 
Published: July 2022

Abstract
Background: The complement system plays a central role in innate immune response with the recognition and elimination of pathogens through direct killing and/or stimulation of phagocytosis. The complement system is composed of a complex proteolytic cascade of more than 50 soluble and membranous proteins among which the complement Factor I (FI) is a key protease that regulates the cascade through inactivation of C3b and C4b and their downstream effect in terminal membrane attack complex (MAC) formation. A deficiency or absence of endogenous FI results in uncontrolled spontaneous activation of the alternative pathway, leading to continuous, massive consumption of complement component 3 (C3). Low levels of C3 may, in turn, reduce phagocytic activity, opsonization, and antibody production, as well as impair immune complex metabolism. As such, FI deficiency can result in an increased susceptibility to infections by encapsulated bacteria and/or an increased incidence of autoimmune and immune-complex diseases. Methods: By using a data harmonization method, we created a repository for quantitative interrogation of FI deficiency phenotype and its associated complement markers across 135 cases. In addition, we generated Cfi-/- rats to establish a model that recapitulates the complement biomarker imbalance observed in FI deficient individuals.Results: Bacterial infections are the most predominant clinical phenotype in FI deficient individuals. Our analysis highlights symptoms often begin early in childhood with ~70% of the cases reported in children < 18 years old, further supporting that FI deficiency is a pediatric disorder. The complement imbalance observed in FI deficient individuals is recapitulated in Cfi-/- rats.Conclusions: We provide the first robust meta-analysis of FI-deficiency of 135 cases described in the literature and established a new tool to evaluate future therapeutic agents for their capacity to treat FI deficiencies.
Assessment the effect of graphene and graphene oxide on antibiotic resistance genes during copper-contained swine manure anaerobic digestion
Authors: Zhang Ranran , Li Jiming , Zhou Liuyuan , Zhuang Haifeng , Shen Sihan , Wang Yuheng 
Published: July 2022

Abstract
The metals added to swine feed to promote livestock growth could be important selectors for antibiotic resistance genes (ARGs) because of metal–antibioticcross-resistance and/or coresistance. This study investigated the effects of grapheme and grapheme oxide on ARGs during the anaerobic reactors containing copper. The abundances of 15 ARGs, 4 mobile genetic elements (MGEs), 5 heavy metal resistance genes (HMRGs), and the bacterial communities were determined.The additives ofgraphene and graphene oxide both can reduce ARGs abundance in varying degrees with the anaerobic reactors that contained a higher concentration of copper. What’s more, graphene decreased the abundances of ARGs more effectively than graphene oxide. Most ARGs significantly correlated with Firmicutes, Bacteroidetes, Spirochaetes, and Verrucomicrobiaat phyla level. Network and redundancy analyses demonstrated that alterations in the bacterial community were mainly associated with the changes in ARGs. In anaerobic digestion products, Firmicutes, Bacteroidetes, and Spirochaetes were enriched lower in graphene reactor than graphene oxide. This may be the main reason that graphene is superior to graphene oxide to reduced ARGs abundance. Additionally, this study demonstrated that ARGs were closely with HMRGs than MGEs in the addition of graphene reactors. Nevertheless, the driver of MGEs in graphene oxide reactors for ARGs are higher than HMRGs. Therefore, we speculatethe decreased of HMRGs by graphene and MGEs by graphene oxide further improved their effects for ARGs reduced.
Climate change impacts on food system security and sustainability in Bangladesh
Authors: Chowdhury Md. Monirul Islam , Rahman Syed Masiur , Amran Md Iqram Uddin Al , Malik Karim , Abubakar Ismaila Rimi , Aina Yusuf Adedoyin , Rahman Sheikh Mohammad Abdur , Khan Maqbool , Muhyedeen Musah Ahmed , Hasan Md. Arif 
Published: July 2022

Abstract
Climate change threatens the security and sustainability of the global food system. In Bangladesh, the fragile food system is strongly being impacted by climate variability and extreme weather events. Estimates indicate that the agricultural sector could lose about USD7.7 billion per annum due to climate change. The average annual rice production could decline by 33% within two decades. However, a few studies investigated the impacts of fluctuating temperature and rainfall, flash floods, drought, and saline water intrusion on the food system and security in an integrated manner. This study examines climate change impacts on food system security and sustainability in Bangladesh. It reviews the country’s food system, the climatic conditions that threaten food security, and impacts climate change on the food systems and the associated vulnerabilities. The study then assesses the existing adaptation initiatives and the extent of their integration among pertinent stakeholders. It concludes that local climate change adaptation strategies and stakeholder collaboration are necessary for reducing climate change impacts on food system security.
Robust Structural Superlubricity under Gigapascal Pressures
Authors: Xu Zhiping , Sun Taotao , Gao Enlai , Jia Xiangzheng , Wang Zhou , Ma Ming , Zheng Quanshui 
Published: July 2022

Abstract
Structural superlubricity (SSL) is a state of contact between two sliding surfaces with no wear and ultralow friction. SSL has been characterized at contacts with van der Waals (vdW) layered materials, while its robustness under high pressure has not been assessed. Here we report experimental results showing that incommensurate vdW interfaces between graphite can maintain the state of SSL under the pressure of no lower than 9.45 GPa, and the vdW contact between a tungsten tip and graphite substrate remains stable up to 3.74 GPa, even higher than the strength of most solids. Beyond this critical pressure, wear is activated, signaling the breakdown of vdW contacts and SSL. This unexpected strong pressure resistance and wear-free feature of SSL signals a wear mechanism beyond the Archard law. Atomistic simulations reveal the microscopic processes of SSL breakdown, which originates from lattice destruction at the vdW contact by pressure-assisted bonding, triggering wear through shear-induced tearing of layered vdW materials. The correlation between the breakdown pressure and material parameters for a number of vdW contacts was analyzed. The results show that the bulk modulus and the first ionization energy, are the most relevant factors, which indicate the combined structural and electronic effects. The critical pressures of several metal/graphite contacts could exceed the strength of metals, demonstrating the robustness of SSL. These findings offer fundamental understandings of wear at the vdW contacts, and could guide the design of SSL-derived applications.
Reprogramming of glycometabolism caused by low-level lead in vascular smooth muscle cells
Authors: Xu Li-Hui , Duan Huan-ren , Zhang Yu , Zhang Tong-jia , Liu Ya-shu , Zhou Jin-sa , Hu Wen-xiu , Zhang Huan , Shi Wan-ying , Sun Su-ju 
Published: July 2022

Abstract
Background: Lead induces cardiovascular disease in humans and animals. Changes in the structure and function of vascular smooth muscle cells (VSMCs) are the cytopathological basis of many cardiovascular diseases. The present study investigated the effects of low-level lead on oxidative stress and carbohydrate metabolism in rat VSMCs. Materials and Results: VSMCs were cultured in media with 0 μM (control group) 、0.25 μM、1 μM lead acetate for 24 h. Low-level lead exposure caused oxidative stress damage to vascular smooth muscle cells, increased level of Reaction oxygen species (ROS) and reduced glutathione (GSH) in VSMCs were detected compared with that in control group (P< 0.05). Compared with the control group, the decreased activity of PKM2, LDH and HK, the key enzymes for oxygen-free oxidation in lead-exposed group (P< 0.05) were detected. The key oxygen-oxidation enzyme PDH in the lead-exposed group was detected and the activity was reduced (P< 0.05), while the PDK1 content increased (P< 0.05). The activity of G-6-PD, a key enzyme of the pentose phosphate pathway, and the product NADPH increased (P< 0.05) in the lead-exposed group. Moreover, the Intracellular glucose content significantly increased in the lead-exposed group (P< 0.05).Conclusion: Low-level lead exposure leads to oxidative stress damage in VSMCs and enhances pentose phosphate pathway flow by improving the metabolic efficiency of the glutathione redox cycle, while disrupts the glycometabolism of VSMCs, inhibits anaerobic and aerobic oxidative processes, causing glycometabolism reprogramming in VSMCs. These findings may be the molecular mechanism for cardiovascular disease induced by low-level lead.
Spatiotemporal differences and influencing factors of high-quality utilization of land resources in the Yellow River Basin of China
Authors: Li Weiming , Cai Zhaoyang 
Published: July 2022

Abstract
High-quality utilization of land resources (HULR) is related to security of land ecosystem and sustainable development of socio-economy. To promote the HULR, we explored the spatiotemporal differences and influencing factors of HULR in the Yellow River Basin (an important ecological barrier in China) by using entropy method, spatial panel regression model, and geographically and temporally weighted regression model. We found that the HULR values were 0.22 to 0.28 from 2008 to 2019, showing an increasing trend with obvious spatiotemporal differences. The spatial connectivity, technological innovation, industrialization, industrial upgrading, and marketization are important factors influencing HULR, and different factors have different spatial effects in different regions. Therefore, the important principle of HULR in the Yellow River Basin is to pursue the coordinated development of human and land according to regional characteristics. We hope that this research can provide references for the HULR around the world.
USP14 promotes colorectal cancer progression by targeting JNK for stabilization
Authors: Li Shangze , Du Xuehua , Ke Shao-bo , Liang Xin-Yi , Gao Jie , Xie Xiao-Xiao , Qi Lin-Zhi , Liu Xue-Yi , Xu Guo-Yuan , Zhang Xiao-Dong , Du Run-Lei 
Published: July 2022

Abstract
MAPK/JNK signaling is pivotal in carcinogenesis. However, ubiquitin-mediated homeostasis of JNK remains to be verified. Here, with results from RNA sequencing (RNA-seq) and luciferase reporter pathway identification, we show that USP14 orchestrates MAPK/JNK signaling and identify USP14 as a deubiquitinase that interacts and stabilizes JNK. USP14 is elevated in colorectal cancer patients and is positively associated with JNK protein and downstream gene expression. USP14 ablation clearly inhibits colorectal tumorigenesis by targeting the MAPK/JNK signaling cascade in vitro and in vivo. Moreover, USP14 expression is induced by TNF-α, forming a feedback loop with JNK and leading to tumor amplification. Our study suggests that elevated expression of USP14 promotes MAPK/JNK signaling by stabilizing JNK, which in turn augments colorectal carcinogenesis, indicating a potential therapeutic target for colorectal cancer patients with increased USP14 expression.
Graphene oxide promotes V-Cu-Ce-ZSM-5 to catalyze SO2 and NO at low-temperature: Performance and Mechanism
Authors: WANG Lemeng , ZHAO Zhikai , WANG Wen , XING Gaoshan , ZENG Fang , qi liqiang 
Published: July 2022

Abstract
A catalyst (V-Cu-Ce-ZSM-5) was explored to simultaneously remove the SO2 and NOx from flue gas by use of the ZSM-5 molecular sieve as the carrier, V and Cu as the active components, and Ce as the additive in low temperature of 150℃. The performance of V-Cu-Ce-ZSM-5 was evaluated for the oxidation of NO and SO2 before and after the addition of graphene oxide (GO). The results showed that V-Cu-Ce-ZSM-5@GO0.5 had the best performance at a reaction temperature of 150°C, and the oxidation efficiency of SO2 and NO were 94.60% and 83.64%, respectively. The multiple structural characterizations (BET, SEM, XRD, and XPS) revealed that the loading of V and Cu with the additive Ce expanded the specific surface area and pore volume of ZSM-5, provided more adsorption sites for SO2 and NO, and had good desulfurization and denitration activity. The addition of GO further improved the dispersibility of active components and auxiliaries, increased the number of active sites in the reaction process, and significantly improved catalytic activity.
One step to stabilize calcium sodium phosphate crystals acting as photocatalysts embedded in a glass matrix
Authors: Kaewdee Pongpen , Tandorn Sujitra , Limpichaipanit Apichart , Chokethawai Komsanti , Suwanboon Sumetha , Chandet Nopakarn , Kanpiengjai Apinun , Rujijanagul Gobwute , Randorn Chamnan 
Published: July 2022

Abstract
Unstable calcium sodium phosphate (CaNaPO4) in aqueous solution can be stabilized and shows photocatalytic activity in a glass matrix. This research presents one-step melt quenching to prepare stable CaNaPO4 crystals in a glass material. The CaNaPO4 glass ceramic was produced with stoichiometric amounts of SiO2, B2O3, P2O5, CaO, Na2O and TiO2 at 1,200 °C for 4 h. The CaNaPO4 glass ceramic samples were confirmed by XRD, SEM, and TEM techniques. The photocatalytic activity of the CaNaPO4 glass ceramic was investigated by monitoring methyl orange degradation with the addition of H2O2. Notably, the CaNaPO4 glass ceramic demonstrates the high-efficiency photocatalytic degradation of methyl orange (MO) under UV irradiation. The CaNaPO4 glass ceramic can be reused several times. After 8 cycles, the catalyst is still stable and effective in decomposing 100% of methyl orange within 5 h/cycle. In addition, the solid phase photocatalytic activity of the CaNaPO4 glass ceramic was examined by bleaching adsorbed MB under UV light within 25 h. It can also inhibit the growth of E. coli bacteria after UV irradiation for 20 minutes. Therefore, the CaNaPO4 glass ceramic might be an alternative photocatalytic material for wastewater treatment.
Anomaly detection by using a combination of generative adversarial networks and convolutional autoencoders
Authors: Luo Xukang , Jiang Ying , Wang EnQiang , Men Xinlei 
Published: July 2022

Abstract
With the development of full digitalization, the amount of time-series data generated by sensors is ever increasing; thus, time-series outlier detection has become crucial. Moreover, in practice, discovering and flagging anomalies is very time-consuming and expensive. To solve this problem, unsupervised anomaly detection methods have often been used in the past, wherein the model is trained with normal data to learn its behavioral patterns. Generative adversarial networks (GAN) can simulate complex and high-dimensional distributions of data and can be used to learn the behavioral patterns of normal data for unsupervised anomaly detection. However, due to the problem of convergence, GAN are difficult to train. Thus, USAD utilize an autoencoder (AE) to undertake the task of the generator and discriminator and enhance the stability during adversarial training by using the AE to alleviate the problem of non-convergence encountered in GAN. Therefore, in this study, we used the USAD’s generative adversarial training architecture combined with convolutional AEs to improve the model’s feature extraction capabilities. In addition, to reduce false-positive outcomes caused by the prominent sharp points in the reconstructed data, we used the exponential weighted moving average method to smooth the reconstruction error, thereby improving the anomaly detection accuracy of the model. Finally, we experimented with real-world time-series data (ECG and 2D gesture) and verified that our approach could improve the accuracy.
Topical Immunomodulators Improve Clinical Signs of Vernal Keratoconjunctivitis and Atopic Keratoconjunctivitis: A Meta-Analysis
Authors: Erdinest Nir , Noyman Dror Ben Ephraim , London Naomi , Morad Yair , Levinger Nadav , Landau David , Lavy Itay , Solomon Abraham , Naroo Shehzad 
Published: July 2022

Abstract
Objective: Topical immunomodulators cyclosporine A (CsA) and tacrolimus have been added in recent years to the armament to control severe chronic allergic ocular diseases such as atopic keratoconjunctivitis (AKC) and vernal keratoconjunctivitis (VKC). This meta-analysis summarizes the randomized controlled trials (RCTs) that utilized topical immunomodulators, to examine their effectiveness at decreasing clinical signs as assessed by clinicians in severe allergic eye disease.Methods: A systematic search identified thirteen studies and a total of 445 patients for inclusion, making this the largest meta-analysis published on the subject.Results: Thirteen RCTs were included. Eleven studies used Cyclosporine A as the treatment, and two used Tacrolimus. In total, 445 participants were included, 76.6% were male. The mean age of the participants was 14 years. All studies reported clinical signs as evaluated by an examining clinician. Signs were usually assessed by anatomical region, with the most common regions being the conjunctiva and the cornea, and the most common signs assessed were hyperemia and papillae. Three studies accounted for over 50% of the meta-analysis's weight. Effect size (d) ranged from -2.37 to -0.03, negative values favoring immunomodulators. Fixed Effect Meta-Analysis returned an SMD of -0.81 (95% CI: [-0.98, -0.65]). However, there was significant heterogeneity (I2=61%, Qw=30.76) in the outcome measure (P=0.0021); therefore, a random-effect meta-analysis was also completed where the pooled SMD was -0.98 (95% CI: [-1.26, -0.69], τ2 = 0.16).Conclusions: This study affirms that immunomodulators effectively treat clinical signs, including blepharitis, conjunctival hyperemia, edema, papillae, and corneal damage in severe ocular allergic disease.