bluuebunny/crossref_metadata_2025_split huggingface dataset:
The cycle ergometer test is not a reliable alternative to the countermovement jump in the assessment of power output
Authors: Peyper Kyle , Olivier Benita , Green Andrew 
Published: June 2022

Background: Rugby union is a physically demanding collision sport that requires optimal neuromuscular functionfor maximal power output, with mechanical power an integral component of performance. Peak power (Pp) andrelative Pp are parameters of neuromuscular function commonly assessed through the countermovement jump(CMJ) as a measure of fatigue. The Wattbike cycle ergometer test (CET) is a non-load bearing method of evaluating lower limb power. The cost-effective CET could therefore offer a viable alternative to the CMJ.
Objectives: This study aimed to determine the concurrent validity of the CMJ and CET.
Methods: Thirty-eight professional rugby union players performed twelve CMJs on a force platform with four loads(bodyweight: BW-CMJ; 20kg: 20-CMJ; 40kg: 40-CMJ and 60kg: 60-CMJ) and a six second peak power (6PPO) CET assessment on a Wattbike ergometer.
Results: CMJ power outputs were [BW-CMJ: Pp - 3101±648 W; 20-CMJ: Pp - 2724±513 W; 40-CMJ: Pp - 2490±496 W; 60-CMJ: Pp - 2238±366 W] and CET [Pp – 1310±161 W]. None of the CMJ-Pp values showed relationships with any CET power variables. Large (r = 0.51-0.63; p = 0.000 – 0.001) relationshipswere found to be between relative CMJ and relative CET power outputs. Bland-Altman plots, which were used todetermine the level of agreement between the two assessments, showed the agreement between the tests waspoor.
Conclusion: Though positive relationships existed between relative CMJ and relative CET power variables, analyses of the level of agreement in the Bland-Altman plots suggest that the two power assessment methods are not interchangeable measures of power.
Congreso Internacional de Periodismo en Debate 2020: Periodismo en tiempos de pandemia
Authors: Orbe Tania 
Published: June 2022

Transformación, reinvención, resiliencia y adaptación para la sostenibilidad de la profesión del futuro.
Esta publicación recoge las memorias del X Congreso Internacional “Periodismo en Debate” que se efectuó del 9 al 14 de noviembre de 2020. El tema central del evento fue: “PERIODISMO EN TIEMPOS DE PANDEMIA Transformación, reinvención, resilencia y adaptación para la sostenibilidad de la profesión del futuro”.
Este evento respondió a la necesidad de desarrollar nuevos formatos para el periodismo en tiempos de pandemia y la reivindicación de los formatos tradicionales como crónicas y reportajes largos en la cobertura de temas relacionados a los derechos humanos como violencia intrafamiliar, femicidio, xenofobia, migración, abuso sexual, entre otros. El Congreso Internacional “Periodismo en Debate” ya lleva diez ediciones y estamos preparando la onceaba edición de aniversario para noviembre de 2021.
V SIMPOSIO EN FITOPATOLOGÍA, CONTROL BIOLÓGICO E INTERACCIONES PLANTA-PATÓGENO
Authors: León-Reyes Antonio 
Published: June 2022

El Colegio de Ciencias e Ingeniería, Politécnico, y la carrera de Agronomía de la Universidad San Francisco de Quito USFQ bajo la filosofía de las Artes Liberales y con el fin de apoyar el desarrollo del sector agrícola y agroindustrial del país organiza el QUINTO SIMPOSIO EN FITOPATOLOGÍA, CONTROL BIOLÓGICO E INTERACCIONES PLANTA-PATÓGENO. El simposio se caracteriza por la exposición de temas de interés técnico científico, con un enfoque en las aplicaciones en las áreas de la fitopatología, control biológico y defensas en las plantas. En estaocasión se abordarán los siguientes temas:
1) Control Biológico:• Mecanismos de hongos y bacterias benéficas para el control de enfermedades.• Microorganismos antagonistas frente a enfermedades vegetales.• Producción masiva de bacterias y hongos benéficos para el control de plagas y enfermedades.
2) Interacciones Planta-Patógeno:• Metabolitos secundarios y ruta del ácido jasmónico en la defensa contra insectos y hongos.• Reconocimiento y rutas de defensa vegetal frente a fitopatógenos de diversos estilos de vida.• Supresión de defensas vegetales mediante efectores microbianos.• Búsqueda de genes de resistencia frente a virus.
3) Fitopatología:• Aislamiento, detección y caracterización de virus asociados a especies vegetales.• Aislamiento, detección y caracterización de patógenos asociados a los cultivos de exportación.• Aislamiento, detección y caracterización de microrganismos de suelo.
4) Diversidad genética:• Diversidad genética de enfermedades• Diversidad genética de bacterias• Diversidad genética de virus
Por su naturaleza, el evento está dirigido a profesionales del sector agrícola, pecuario, biotecnológico e investigativo, al igual que a estudiantes de las distintas instituciones vinculadas al sector. El objetivo de este tipo de evento es conocer sobre las diversas aplicaciones de la fitopatología en el sector, que ayuden al sector Agrícola a resolver los diversos problemas prácticos usando los conocimientos integrales de las interacciones planta patógeno. Durante el curso, se cubrirán varios temas relacionados a las áreas de microbiología, biología molecular, biodiversidad, enfocado en las interacciones planta-patógeno.
Teachers' perceptions of the factors influencing rural school Grade 12 Business Studies learner performance in the National Senior Certificate
Authors: Mtshali Muntuwenkosi Abraham , Ngwenya Jabulisile Cynthia , Myende Thandanani Hansford 
Published: June 2022

The purpose of this study is to examine teachers’ perceptions of teacher factors affecting the dwindling Grade 12 learners’ performance in Business Studies National Senior Certificate (NSC) examinations at the rural Umbumbulu circuit of Umlazi district, in the province of KwaZulu-Natal, South Africa. The study employed a qualitative research methodology to explore teachers’ perceptions. Five Grade 12 teachers were purposively selected from five rural secondary schools that offered Business Studies as a subject of teaching and learning in the Umbumbulu circuit. The case study research design was used to focus on a few participants who had lived experiences of teaching Business Studies at Grade 12 in rural schools and could relate to dominant factors influencing learner performance in this subject. Data were generated through faceto- face, semi-structured interviews, and thematic analysis was used as a method of analysing qualitative data with the purpose of identifying salient traits in data that could develop into themes. The study found that teacher factors influencing learner performance in Grade 12 Business Studies were teacher approaches to teaching Business Studies, timetabling and impediments to innovative teaching and assessment in the form of rural contextual factors such as large classes and a shortage of textbooks. The study nurtures awareness of teacher factors influencing rural school learners’ performance in Grade 12 Business Studies, so that Business Studies teachers in emerging economies can think of ways to address these factors to improve learner performance.
Adapting to technology tools in a learning environment: A case study of first-year students at a traditional African university
Authors: Olaitan Olutoyin , Mavuso Nosipho 
Published: June 2022

The introduction of technology to teaching and learning has brought about modernisation of academic activities. The drastic paradigm shift faced by the education sector is inevitable, especially as the impact of the much-touted Fourth Industrial Revolution is being felt in key sectors of the economy. This reality imposes the need for technology-enhanced learning for tertiary students as it represents the future of the workplace for which they are being prepared at university. For effective learning to take place, institutions need to incorporate technological tools in their teaching and learning. Adapting to a myriad of technology tools can be challenging, especially for less privileged learners who might be adjusting to tertiary life and previously have not been exposed to the basics of computers and other technology tools. This challenge is further compounded by the fact that most of these learners are experiencing the independence of tertiary education for the first time and are still struggling to balance their academic workload with the anxieties of social blending. This paper investigated how first-year students at a traditional, previously disadvantaged university in the Eastern Cape province, South Africa, adapted to Blackboard Learn (also referred to as WiseUP), the learning management system (LMS) adapted for blended learning at the university. The paper explored the challenges faced by the new students and thereafter employed a combination of the Theory of Planned Behaviour and the Technology Acceptance Model to build a new model, which reveals the critical factors that influence students to embrace technology. This model will assist lecturers, faculty and student support structures to understand the underpinning factors that influence first-year students to embrace the technology tool, namely, the university’s LMS. Quantitative data collection and analysis were used in the case study, which was conducted with two groups of first-year students in management and information technology courses. Results show the significant factors that influence students’ attitudes positively towards the use of technology for learning.
Factors influencing data saturation in qualitative studies
Authors: Mwita Kelvin 
Published: June 2022

This study aims to evaluate the factors that influence data saturation in qualitative studies. The study adopted a systematic literature review of 24 journal articles published between 2018 and 2022. The articles were obtained from a Google scholar database. The findings point to five factors that affect data saturation namely, pre-determined codes and themes, sample size, relevancy of research subjects (respondents), number of research methods, and length of data collection sessions. It is argued in this paper, therefore, that in order to attain data saturation, researchers should consider multiple factors that may affect data saturation in order to increase the validity of qualitative studies.
Здоровье экосистем: понятие, методологические подходы, критерии оценки
Authors: Кузнецова Т. В. , Манвелова А. Б. 
Published: June 2022

Всё возрастающая антропогенная нагрузка на водные экосистемы создаёт угрозы экологической безопасности, и в этой связи важным является экосистемный подход к эксплуатации природных ресурсов с целью разработки комплексных регулирующих мер в природоохранной сфере. Термин «здоровье экосистемы» широко используют в оценке экологического состояния акваторий представители зарубежных научных сообществ (HELCOM, ICES, OSPAR, MEDPOL), однако нечасто применяют отечественные исследователи. Концепция «здоровье экосистемы» не является новой парадигмой: она не только активно обсуждается с начала 2000-х гг. в научной литературе, но и закреплена в долговременных документах Евросоюза и в Водной рамочной директиве ЕС по стратегии сохранения окружающей среды. В статье на основе обзора существующих литературных данных представлены основные понятия, подходы и критерии оценки экологического состояния (здоровья) водных экосистем. Подчёркнуто, что оценка здоровья экосистем зависит от целей и задач экологических исследований, с чем связана применяемая методология и, соответственно, выбор методов и показателей, характеризующих состояние экосистемы. В обзоре рассмотрены понятие «здоровье организмов» и некоторые его атрибуты: поддержание гомеостаза, причинно-следственные связи в континууме здоровье — болезнь, функциональные адаптации. Представлен сравнительный анализ ряда подходов к оценке здоровья рек и морских акваторий. Рассмотрены различные показатели, комплексные индексы, биомаркеры экспозиции и эффектов, указывающие на подверженность водных экосистем изменениям в результате природных и антропогенных воздействий. Отдельное внимание обращено на необходимость применения комплексного экосистемного подхода в анализе состояния водных экосистем, что будет способствовать интегральной оценке последствий деятельности человека для целостности экосистем. На основе опыта выполнения международного проекта BONUS+/BEAST представлен комплексный биомаркерный подход к определению здоровья биоиндикаторов с последующей интерпретацией данных о состоянии здоровья экосистем, в которых эти организмы обитают. Авторы надеются, что обзор будет интересен как специалистам в области экологии водных экосистем, так и представителям природоохранных организаций, ответственным за проведение экологических экспертиз.
Effective Inclusion Practices for Neurodiverse Children and Adolescents in Informal STEM Learning: A Systematic Review Protocol
Authors: Jenson Ronda Jean , Lee Michele Sky , Day Arden D , Hughes Amy E , Maroushek Emma E , Roberts Kelly D 
Published: June 2022

Abstract
Background: Informal learning experiences in science, technology, engineering, and math (STEM) can enhance STEM learning that occurs in formal educational settings and curricula as well as generate enthusiasm for considering STEM careers. The aim of this systematic review is to focus on the experiences of neurodiverse students in informal STEM learning. Neurodiversity is a subgroup of neurodevelopmental conditions, such as autism, attention deficit disorder, dyslexia, dyspraxia, and other neurological conditions. The neurodiversity movement regards these conditions as natural forms of human variation, as opposed to dysfunction, and recognizes that neurodiverse individuals possess many strengths relevant to STEM fields. Methods: The authors will systematically search electronic databases for relevant research and evaluation articles addressing informal STEM learning for K-12 children and youth with neurodiverse conditions. Eight databases and content-relevant websites (e.g., informalscience.org) will be searched using a predetermined search strategy and retrieved articles will be screened by two members of the research team. Data synthesis will include meta-analysis and meta-synthesis techniques, depending on the quantitative, qualitative, or mixed methods designs of the studies. Discussion: The synthesis of the findings resulting from various research and evaluation designs, across the K-12 age span, and across various informal STEM learning contexts, will lead to depth and breadth of understanding of ways to improve informal STEM learning programs for neurodiverse children and youth. The identification of informal STEM learning program components and contexts shown to yield positive results will provide specific recommendations for improving inclusiveness, accessibility, and STEM learning for neurodiverse children and youth. Systematic Review Registration: The current study has been registered in PROSPERO. Registration number: CRD42021278618
Molecular and Clinical Profile of patients referred as Noonan or Noonan-like Syndrome in Greece: a cohort of 86 patients
Authors: Papadopoulos George , Papadopoulou Anna , Kosma Konstantina , Papadimitriou Anastasios , Papaevangelou Vassiliki , Kanaka-Gantenbein Christina , Bountouvi Evangelia , Kitsiou-Tzeli Sophia 
Published: June 2022

Abstract
Noonan syndrome (NS) is an autosomal dominant disorder characterized by clinical and genetic heterogeneity. It belongs to a wider group of pathologies, Rasopathies, due to the implication of mutations in genes encoding components of the Ras/MAPK signalling pathway. Recording the genetic alterations across populations helps assessing specific features to specific genes which is essential for better disease’s recognition, prognosis and monitoring. Herein, we report the clinical and molecular data of a Greek cohort comprising of 86 NS or NS-like patients admitted at a single tertiary Centre in Athens, Greece. The analysis was performed using Sanger and Next-Generation-Sequencing, comprising 14 different genes. The mutational rates of the confirmed NS-associated genes in the Greek NS population are: PTPN11 32.5%; RIT1 5.8%; SOS1 4.7%; BRAF 1.2%; CBL 1.2%; KRAS 1.2%; MAP2K1 1.2%; RAF1 1.2%; SHOC2 1.2%, corresponding to 50% of positivity in total NS population. The genotype-phenotype analysis showed statistically significant differences regarding craniofacial dysmorphisms (p=0.005) and pulmonary valve stenosis (PS) (p<0.001) between patients harboring a mutation in any of the tested genes and mutation-free patients. Patients with at least one mutation had 6.71 times greater odds to develop PS compared to mutation-negative patients [OR=6.71, 95%; CI= (2.61, 17.27)]. PTPN11 positive patients showed higher frequency of epicanthal folds (p=0.004), ptosis (p=0.001) and coarseness (p=0.001) and lower frequency of neurological findings (p=0.006) , compared to patients with carrying mutations in other genes. Conclusion: Craniofacial dysmorphismand PS prevail among mutation positive compared to mutation negative NS and NS-like patients while neurological defects are less common in PTPN11 mutated NS patients compared to patients with mutations in other genes The significant prevalence of the Ras/MAPK mutations (17.4%), other than PTPN11, in Greek patients, highlights the necessity of a wider spectrum of molecular diagnosis.
Thermally Radioactive Bioconvection of Magnetized Sutterby Nanofluid over a Stretching Cylinder
Authors: Awan Aziz Ullah , Shah Syed Asif Ali , Waqas Hassan 
Published: June 2022

Abstract
The current article analyzes bioconvection aspects in Sutterby nanofluid flow across stretching cylinder with conductivity that varies with temperature. The non-linear thermal radiation and higher-order slip is scrutinized. The behavior of mass diffusivity and activation energy is investigated in this communication. The main object of this article is to enhance the heat transformation rate. A system of PDEs addresses the current physical problem. The appropriate similarity transformation reduces the PDEs system to the ODEs system. The set of non-linear ODEs is numerically solved utilizing bvp4c code built-in MATLAB. The result of the problem is discussed graphically. It is found that velocity profile diminishes for the boosted values of 1st order and 2nd order slips parameters while temperature enhances by increasing the values of non-linear thermal radiations. Moreover, the value of Nusselt number, skin fraction coefficient, and Sherwood number are evaluated through tables.
High-Dose Chemotherapy with Stem Cell Rescue to Treat Stage III Homologous Deficient Breast Cancer: Factors Influencing Clinical Implementation
Authors: Verbeek Joost Gijs Edmond , de Jong Vincent M.T. , Wijnja Hanna M. , Jager Agnes , Linn Sabine C. , Retèl Valesca P. , Harten Wim H. van 
Published: June 2022

Abstract
Purpose: High-dose chemotherapy with autologous stem cell rescue (HDCT) is a promising treatment for patients with stage III, HER2-negative, homologous recombination deficient (HRD) breast cancer. Clinical effectiveness and cost-effectiveness are currently under investigation in an international multicenter randomized controlled trial. To increase the chance of successful introduction of HDCT into daily clinical practice, we aimed to identify relevant factors for smooth implementation using an early comprehensive assessment framework. Methods: This is a qualitative, multi-stakeholder, exploratory research using semi-structured interviews guided by the Constructive Technology Assessment model, which evaluates the quality of a novel health technology by clinical, economic, patient-related, and organizational factors. Stakeholders were recruited by purposeful stratified sampling and interviewed until sufficient content saturation was reached. Two researchers independently created themes, categories, and subcategories by following inductive coding steps, these were verified by a third researcher. Results: We interviewed 28 stakeholders between June 2019 and April 2021. In total, five overarching themes and seventeen categories were identified. Important findings for optimal implementation included the structural identification and referral of all eligible patients, early integration of supportive care, multidisciplinary collaboration between- and within hospitals, (de)centralization of treatment aspects, the provision of information for patients and healthcare professionals, and compliance to new regulation for the BRCA1-like test.Conclusions: In anticipation of a positive reimbursement decision, we recommend to take the highlighted implementation factors into consideration. This might expedite and guide high-quality equitable access to HDCT for patients with stage III, HER2-negative, HRD breast cancer in the Netherlands.
Spatiotemporal mapping of malaria incidence in Sudan using routine surveillance data
Authors: Elagali Ahmed , Ahmed Ayman , Makki Nada , Ismail Hassan , Ajak Mark , Alene Kefyalew Addis , Weiss Daniel , Mohammed Abdalla Ahmed , Abubakr Mustafa , Cameron Ewan , Gething Peter , Elagali Asmaa 
Published: June 2022

Abstract
Malaria is a serious threat to global health, with over 95% of the cases reported in 2020 by the World Health Organization in African countries, including Sudan. Sudan is a low-income country with a limited healthcare system and a substantial burden of malaria. The epidemiology of malaria in Sudan is rapidly changing due to factors including the rapidly developing resistance to drugs and insecticides among the parasites and vectors, respectively; the growing population living in humanitarian settings due to political instability; and the recent emergence of Anopheles stephensi in the country. These factors contribute to changes in the distribution of the parasites species as well as malaria vectors in Sudan, and the shifting patterns of malaria epidemiology underscore the need for investment in improved situational awareness, early preparedness, and a national prevention and control strategy that is updated, evidence based, and proactive. A key component of this strategy is accurate, high-resolution endemicity maps of species-specific malaria. Here, we present a spatiotemporal Bayesian model, developed in collaboration with the Sudanese Ministry of Health, that predicts a fine-scale (1 km × 1 km) clinical incidence and seasonality profiles for Plasmodium falciparum and Plasmodium vivax across the country. We use monthly malaria case counts for both species collected via routine surveillance between January 2017 and December 2019, as well as a suite of high-resolution environmental covariates to inform our predictions. These epidemiological maps provide a useful resource for strategic planning and cost-effective implementation of malaria interventions, thus informing policymakers in Sudan to achieve success in malaria control and elimination.