bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploiting surface textures dynamics for dry friction control
Authors: Menga N. , Bottiglione F. , Carbone G. 
Published: October 2022

AbstractWe study the dynamic behavior of a lattice of bristle-like elastic elements disposed at the interface between a rigid still substrate and a rigid sliding slab, in steady conditions. Due to normal and frictional interactions with the moving slab, complex bristles dynamics occur, which may eventually alter the overall frictional response of the structured interface. Indeed, up to three main mechanisms of friction control can be identified, depending on the specific bristles dynamics: the relative velocity-dependent modulation of local friction force; the misalignment between the local relative velocity and the slab velocity, due to the emergence of transverse vibration; the local friction coefficient variation due to the normal load acting on the bristle. Results show that, depending on the interface dynamic properties (i.e., bristles stiffness, normal load, slab velocity, etc.), a significant reduction of the friction force opposing the slab motion can be achieved, also involving self-excited bristle vibration. Since the present formulation is scale independent, this result may suggest possible mechanisms of friction control in different practical application fields, ranging from bio-inspired micro-structured interfaces to macro-scale features, such as brush seals in electric motors.
Natural acylated flavonoids: their chemistry and biological merits in context to molecular docking studies
Authors: Essa Ahmed F. , Teleb Mohamed , El-Kersh Dina M. , El Gendy Abd El-Nasser G. , Elshamy Abdelsamed I. , Farag Mohamed A. 
Published: October 2022

AbstractAcylated flavonoids are widely distributed natural dietary bioactives with several health attributes. A large diversity of acylated flavonoids with interesting biological potentialities were reported. Of these, 123 compounds with potential antimicrobial, antiparasitic, anti-inflammatory, anti-nociceptive, analgesic and anti-complementary effects were selected from several databases. Based upon these data, the possible mechanistic evidence for their effects were reported. Generally, aromatic acyls i.e., galloyl derivatives appeared to improve efficacy through enhancement of the binding affinities to molecular targets due to plenty of donating and accepting centers. Docking simulations conducted by Molecular Operating Environment (MOE) of acylated flavonoids revealed that compound 12 is at the top of the list into the antibacterial target DNA gyrase subunit B (GyrB), from E. coli, followed by compounds 10, 4 and 23. Compounds 81, 88, 96, 92, 99, 100, 102 and 103 have the strongest binding affinities into Human matrix metallopeptidase (MMP) 2 and 9 catalytic domains. Compound 103 exerted the most balanced predicted dual MMP-2/MMP-9 inhibition action. Compound 95 recorded the strongest binding affinity into metabotropic glutamate receptor (mglur1) with the lowest energy conformer. The data presented in this review suggests that these candidate acylated flavonoids ought to be considered in future drug developments especially as anti-inflammatory and antimicrobial agents.
Is the World a Just Place? The Italian Adaptation of the Personal and General Belief in a Just World Scales
Authors: Esposito Ciro , Di Martino Salvatore , Arcidiacono Caterina , Di Napoli Immacolata 
Published: October 2022

AbstractThe study presents the Italian adaptation of the Personal and General Belief in a Just World (P-BJW and G-BJW) Scales. Dalbert and colleagues developed these scales to capture the belief in a just world for oneself and a just world in general. After the translation and back-translation, the P-BJW and G-BJW scales were administered first to a pilot sample of 213 university students and then to a national sample of 2683 Italian people. Results showed that it was necessary to make some revisions to the predicted two correlated factor structure. These changes entailed correlating the error terms for some manifest variables and removing the first item of the P-BJW factor. The final structure of the P-BJW and G-BJW scales presented satisfactory indexes of model fit as well as high reliability and moderate validity values. Additionally, this structure proved to fit the data better than an alternative one-factor or a bi-factor model with two orthogonal-specific factors. As predicted, well-being strongly predicted scores on the BJW, but age and gender did not. Multigroup comparisons among Northern, Central, and Southern Italy respondents indicated that Italian people interpret scale items equivalently, regardless of their geographical location. Introducing the P-BJW and G-BJW scales to the Italian justice scholarship is very useful to unpack the reasons why Italy reports lower levels of social justice than other European countries and also to investigate the link between justice, well-being, and other socio-psychological variables.
Associations of metal profiles in blood with thyroiditis: a cross-sectional study
Authors: Luo Yaosheng , Zeng Huixian , Ye Yanshi , Yu Genfeng , Song Cheng , Liu Siyang , Chen Xingying , Jiang Yuqi , Duan Hualin , Li Yue , He Shengqing , Chen Zhi , Liu Lingling , Liang Yongqian , Lin Xu , Wan Heng , Shen Jie 
Published: October 2022

AbstractAutoimmune thyroiditis (AIT) is increasingly common, and serological markers include thyroid peroxidase antibody (TPOAb) and thyroglobulin antibody (TgAb). To determine if selected metals influence thyroiditis antibody positivity, this cross-sectional study investigated associations between metals and thyroiditis antibody status. Healthy individuals (n = 1104) completed a questionnaire and underwent checkups of anthropometric parameters, thyroid function status, and levels of seven metals in blood (magnesium, iron, calcium, copper, zinc, manganese, and lead). Associated profiles of glyco- and lipid metabolism were also established. Logistic regression and restricted cubic spline (RCS) regression analysis were applied to adjudge associations between metals and TPOAb and TgAb status. It was found that, after adjusting for likely cofounding factors, participants with antibody positivity had significantly lower serum concentrations of magnesium and iron. When serum magnesium levels were analyzed in quartiles, the odds ratios of quartile 4 were 0.329–fold (95% confidence interval (CI): 0.167–0647) and 0.259-fold (95% CI 0.177–0.574) that of quartile 1 regarding TPOAb and TgAb positivity (P = 0.004, 0.003). After adjustment, the RCS analysis detected nonlinear associations between iron and TPOAb and TgAb positivity (P < 0.01, both). In stratified analyses, these associations regarding magnesium and iron remained for women of reproductive age, but not for postmenopausal women and men. We conclude that lower serum levels of magnesium and iron are associated with incremental positivity of thyroiditis antibodies and may be among the most important metals contributing to AIT in women of reproductive age.
Psychological Profile, Emotion Regulation, and Aggression in Police Applicants: A Swiss Cross-Sectional Study
Authors: Ceschi Grazia , Meylan Stephanie , Rowe Charlotte , Boudoukha Abdel Halim 
Published: October 2022

AbstractAlthough police officers are recurrently exposed to traumatic situations during their duties, only a minority report notable emotional complaints. This can be explained either by strong emotional coping skills or by a repressive self-presentation style. The current study describes the emotional profile and personality dispositions of police candidates (i.e., prior to exposure to occupational trauma) and explores the possible association between these personal characteristics and predisposition to aggression. In a cross-section design, 149 Swiss police applicants were compared to 110 individuals of the community matched by age, gender and level of education. Validated scales were used to obtain self-report markers of emotions and attitudes (anxiety, happiness/depression, aggressive attitudes) and personal dispositions (sensitivity to reinforcement, impulsivity, social desirability). Compared to civilian individuals, police candidates self-reported being happier, less anxious, less aggressive, and less impulsive. They declared being less sensitive to reinforcement, whether punishment or reward, but showed a higher degree of social desirability. Their aggressive tendencies were influenced by anxiety, urgency, and sensitivity to reward. The findings will be discussed within the framework of a diathesis-stress model of emotion regulation. It suggests that the repressive coping style described in police candidates may be a protective factor against negative and overwhelming emotions in the short term, but a risk factor for emotional imbalance in the long term, particularly if exposed to recurrent adverse events.
Trends and Clinical Characteristics of HIV and Cerebrovascular Disease in Low- and Middle-Income Countries (LMICs) Between 1990 and 2021
Authors: Ransley George , Zimba Stanley , Gadama Yohane , Saylor Deanna , Benjamin Laura 
Published: October 2022

AbstractPurpose of the ReviewTo describe trends and clinical characteristics of HIV and cerebrovascular disease between 1990 and 2021 in LMICs and identify the gaps in our understanding.Recent FindingsIn the era of antiretroviral therapy (ART), people living with HIV (PLWH) live longer and risk excess cerebrovascular events due to ageing and HIV-driven factors. Despite the highest burden of HIV infection in low-to-middle income countries, there is underreporting in the literature of cerebrovascular events in this population. We systematically reviewed published literature for primary clinical studies in adult PLWH and cerebrovascular disease in LMICs.SummaryThe clinical phenotype of cerebrovascular disease among PLWH over the last three decades in LMICs has evolved and transitioned to an older group with overlapping cerebrovascular risk factors. There is an important need to increase research in this population and standardise reporting to facilitate understanding, guide development of appropriate interventions, and evaluate their impact.
A case of percutaneous transhepatic stomal varices embolization and partial splenic artery embolization for rectal cancer after CAPOX/BEV chemotherapy: the summary of the stomal varices related to oxaliplatin administration
Authors: Mizukami Shoichiro , Shonaka Tatsuya , Tani Chikayoshi , Ihara Kazuki , Takeda Tomohiro , Ohara Mizuho , Hasegawa Kimiharu , Tanino Mishie , Sawada Koji , Sumi Yasuo 
Published: October 2022

AbstractCapecitabine and oxaliplatin (CAPOX) plus bevacizumab (BEV) therapy (CAPOX/BEV) is a standard treatment recommended as the first-line treatment for colorectal cancer recurrence. Recently, sinusoidal obstruction syndrome (SOS) and resulting portal hypertension have been reported as important side effects of oxaliplatin. We herein report a rectal cancer patient who underwent percutaneous transhepatic stoma variceal embolization (PTO) and partial splenic artery embolization (PSE) for stomal variceal bleeding and splenomegaly due to portal hypertension caused by SOS after CAPOX therapy. A 43-year-old man who underwent robot-assisted laparoscopic abdominoperineal resection for advanced lower rectal cancer was started on CAPOX/BEV therapy for early recurrence 1 month after surgery. In the sixth course, splenomegaly rapidly worsened, stomal varices appeared, and the stoma began bleeding. At 5 months after the appearance of stomal varices, the splenomegaly worsened, the frequency of stomal bleeding increased, and PTO was performed. Five months later, PSE was performed for splenomegaly and thrombocytopenia. At 5 months since the PSE, the stoma bleeding has not recurred, and the thrombocytopenia has been corrected. The patient has been able to continue chemotherapy. We suggest that staged treatment by PTO and PSE be considered an important treatment option for stomal varices and splenomegaly associated with SOS.
Peatland Plant Functional Type Effects on Early Decomposition Indicators are Non-Pervasive, but Microhabitat Dependent
Authors: Sahar Najam e , Robroek Bjorn J. M. , Mills Robert T. E. , Dumont Marc G. , Barel Janna M. 
Published: October 2022

AbstractOmbrotrophic peatlands are important long-term sinks for atmospheric carbon as plant productivity exceeds litter decomposition. Changes in plant community composition may alter decomposition rates through alterations in microbial communities and activity. Such plant community driven changes in decomposition rates may however differ between microhabitats. Nevertheless, the microhabitat-context-dependency of plant community composition effects on decomposition remains poorly understood. We used a long-term (> 10 year) plant removal experiment to study how vascular plant functional types (PFTs, i.e. graminoids and ericoids) influence decomposition processes in wet lawns and hummocks. We employed the Tea Bag Index (TBI) as an indicator for early litter decomposition and carbon stabilization and assessed the potential activity of five hydrolytic extracellular enzymes (EEAs) as indicators for microbial activity. PFT removal had no effect on the TBI decomposition rate constant (k), nor on the stabilization factor (S). Yet, k increased slightly when both PFTs were absent. In the lawns, we observed higher values of k and S as compared to hummocks. PFT composition influenced four out of five hydrolytic EEAs that can drive decomposition. Yet, this influence was non-pervasive and microhabitat dependent. In wet lawns, PFT removal generally increased enzyme activities, while opposite trends were detected in the hummocks. Our results suggest an important role for vegetation change, through their influence on enzyme activity, along the lawn-hummock gradient in regulating decomposition processes in northern peatlands. This implies that potential consequences of vegetation changes on organic matter turnover, hence the peatland carbon sink function, cannot be generalized across peatland microhabitats.
Evolution of Alkali Release by an Illitic Rock for Use as Supplementary Cementitious Material
Authors: Lemma Roxana , Marfil Silvina , Rahhal Viviana 
Published: October 2022

AbstractThe levels of CO2 emissions generated by the cement industry and the growth in demand for its products have led to a search for ways to reduce these emissions. The use of supplementary cementitious materials has become one of the solutions proposed for this problem. Illite, which is found all over the world, is a possible supplementary cementitious material. Before illite can be used, it must be milled and treated thermally in order to activate it, so that the alkalis (Na+ and K+) are free and available to react. Alkalis in cement participate in deleterious reactions (alkali-silica reaction) or have a beneficial effect (alkaline activation). The alkalis present in the rocks can play an active role in these phenomena, however. In addition, the material could be influenced by the alkaline environment produced by the cement. The current study was aimed at analyzing whether an alkali release occurs and if so, how it is affected when a milled and thermally treated illitic rock is in contact with water or an alkaline solution. The material was characterized by X-ray fluorescence, polarizing microscopy, and X-ray diffraction (XRD). The sample was treated thermally at 300, 600, and 900°C, and the thermal activation was evaluated through XRD, density, and Atterberg limits. The evolution of alkali release was studied by determining the sodium and potassium concentration of contact water obtained by mixing the samples with different pH solutions for various lengths of time. In addition, the calcium concentration was determined. The concentrations of sodium and potassium in the contact water were determined by flame photometry, and of calcium by EDTA (ethylenediaminetetraacetic acid) titration. The results showed that with increasing age, increasing solution pH, and higher treatment temperatures, alkali release occurred and increased, whereas Ca2+ concentration decreased.
Discovery of peculiar radio morphologies with ASKAP using unsupervised machine learning
Authors: Gupta Nikhel , Huynh Minh , Norris Ray P. , Rosalind Wang X. , Hopkins Andrew M. , Andernach Heinz , Koribalski Bärbel S. , Galvin Tim J. 
Published: October 2022

Abstract
We present a set of peculiar radio sources detected using an unsupervised machine learning method. We use data from the Australian Square Kilometre Array Pathfinder (ASKAP) telescope to train a self-organizing map (SOM). The radio maps from three ASKAP surveys, Evolutionary Map of Universe pilot survey (EMU-PS), Deep Investigation of Neutral Gas Origins pilot survey (DINGO), and Survey With ASKAP of GAMA-09 + X-ray (SWAG-X), are used to search for the rarest or unknown radio morphologies. We use an extension of the SOM algorithm that implements rotation and flipping invariance on astronomical sources. The SOM is trained using the images of all ‘complex’ radio sources in the EMU-PS which we define as all sources catalogued as ‘multi-component’. The trained SOM is then used to estimate a similarity score for complex sources in all surveys. We select 0.5% of the sources that are most complex according to the similarity metric and visually examine them to find the rarest radio morphologies. Among these, we find two new odd radio circle (ORC) candidates and five other peculiar morphologies. We discuss multiwavelength properties and the optical/infrared counterparts of selected peculiar sources. In addition, we present examples of conventional radio morphologies including: diffuse emission from galaxy clusters, and resolved, bent-tailed, and FR-I and FR-II type radio galaxies. We discuss the overdense environment that may be the reason behind the circular shape of ORC candidates.
Robotic rotorcraft
Authors: Austin R. G. 
Published: October 2022

A few of us, like Tennyson, have the gift of foreseeing the future. (see Fig. I). Another few, like Juan de la Cierva have the gift of delivering the future. They are the innovators.Those who know Tennyson's verse will recall that his vision was of transportation by air of people and freight and also sadly of weapons. These were the tasks for which aircraft have primarily been developed – that is until recently.Let us move back a few years from Cierva's day to view the work of another innovator – Von Karman. His machine was a harbinger of the future in that it was not designed for a transport task but for a surveillance task (Fig. 2). It did not survive for long since Von Karman lacked the light-weight, compact, electro-optical sensors available today and he was forced to carry aloft two mk 1 eyeballs attached to a heavy and bulky man.
Strongyloidiasis – diagnostic and therapeutic dilemmas in hyperinfection patients: a case series
Authors: Balen Topić M. , Grubišić B. , Kovačević E. , Sviben M. , Santini M. 
Published: October 2022

Abstract
The helminth infection caused by Strongyloides stercoralis is widespread in tropical regions, but rare in European countries. Unfamiliarity with the disease and diagnostic obstacles could contribute to its lethal outcome. Frequent use of corticosteroids during the COVID-19 pandemic could increase its significance. The aim of this retrospective descriptive study was to explore disease patterns and discuss clinical dilemmas in patients with S. stercoralis hyperinfection treated at the University Hospital for Infectious Diseases ‘Dr. Fran Mihaljević’ in Zagreb, Croatia, between 2010 and 2021. Five out of 22 (22.7%) immunosuppressed patients treated due to strongyloidiasis developed hyperinfection. All patients were male, median 64 years; four were immunosuppressed by corticosteroids (although ileum resection could have been the trigger in one) and one by rituximab. The diagnosis was established after a median of 1.5 months of symptom duration, accidentally in all patients, by visualizing the parasite in the gastric/duodenal mucosa in four cases, and bronchial aspirate in one. All patients were cachectic, four out of five had severe hypoalbuminemia and all suffered secondary bacterial/fungal infection. Despite combined antibiotic, antifungal and antihelmintic therapy, three out of five of the patients died, after failing to clear living parasites from stool samples. We can conclude that significant delays in diagnosis and lack of clinical suspicion were observed among our patients with the most severe clinical presentations of strongyloidiasis. Although being beyond diagnostic recommendations for strongyloidiasis, an early upper gastrointestinal endoscopy with mucosal sample analysis could expedite diagnosis in severe, immunosuppressed patients. The persistence of viable parasites in the stool despite antihelmintic therapy should be further investigated.
Reply to Spears’s ‘The Asymmetry of Population Ethics’
Authors: Aaron Jonas H. 
Published: October 2022

AbstractIs the procreation asymmetry intuitively supported? According to a recent article in this journal, an experimental study suggests the opposite. Dean Spears (2020) claims that nearly three-quarters of participants report that there is a reason to create a person just because that person’s life would be happy. In reply, I argue that various confounding factors render the study internally invalid. More generally, I show how one might come to adopt the procreation asymmetry for the wrong reasons by misinterpreting one’s intuitions.
Misplaced Trust and Distrust: How Not to Engage with Medical Artificial Intelligence
Authors: Starke Georg , Ienca Marcello 
Published: October 2022

AbstractArtificial intelligence (AI) plays a rapidly increasing role in clinical care. Many of these systems, for instance, deep learning-based applications using multilayered Artificial Neural Nets, exhibit epistemic opacity in the sense that they preclude comprehensive human understanding. In consequence, voices from industry, policymakers, and research have suggested trust as an attitude for engaging with clinical AI systems. Yet, in the philosophical and ethical literature on medical AI, the notion of trust remains fiercely debated. Trust skeptics hold that talking about trust in nonhuman agents constitutes a category error and worry about the concept being misused for ethics washing. Proponents of trust have responded to these worries from various angles, disentangling different concepts and aspects of trust in AI, potentially organized in layers or dimensions. Given the substantial disagreements across these accounts of trust and the important worries about ethics washing, we embrace a diverging strategy here. Instead of aiming for a positive definition of the elements and nature of trust in AI, we proceed ex negativo, that is we look at cases where trust or distrust are misplaced. Comparing these instances with trust expedited in doctor–patient relationships, we systematize these instances and propose a taxonomy of both misplaced trust and distrust. By inverting the perspective and focusing on negative examples, we develop an account that provides useful ethical constraints for decisions in clinical as well as regulatory contexts and that highlights how we should not engage with medical AI.