bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Implementation of Environmental Management System to Moderate the Relationship Between the Green Strategy and Company Performance
Authors: Hasugian Hotbin , Murwaningsari Etty , Augustine Sudibyo Yvonne 
Published: November 2022

Introduction: The aspects of the highest pollution levels required a green strategy solution and the implementation of an Environmental Management System to improve the company's performance. This study aims to test and analyze environmental management systems' green strategy and implementation. Method: This study uses primary data collected using questionnaires from respondents using the Purposive sampling technique. The number of questionnaires that can be used is as many as 142, with the company analysis unit of State-Owned Enterprises and private companies included in the green industry list from 185 total questionnaires. Data were processed and analyzed using Structural Equation Modeling (SEM) by the alternative Partial Least Square (PLS) method. Result: The green strategy affects the company's performance. Meanwhile, applying the Environment Management System has no effect as a reinforcement of the relationship of green strategy on the company performance. The results of this study are expected to contribute to the company’s strategy, state-owned enterprises, and private companies in determining green-oriented vision and goals. Conclusion: The Green strategy impacts the company's performance; it is proven that a good green plan will increase the company's performance produced by state-owned enterprises. A low green method will decrease the performance of the company made by state-owned enterprises and private industrial companies. The implementation of Environmental Management Systems cannot increase the impact of the green strategy on the productivity of industrial organizations, state-owned enterprises, and private companies.
Livskvalitet i salmer og visdomslitteratur
Authors: Rosendal Bent 
Published: November 2022

Synet på ‘livskvalitet’ (ganske vist en anakronistisk, men dog relevant kategori) i GT har markant forskelig udseende i hhv. salme- og i visdomstraditionen, hhv. en guddommelig gave og en menneskelig opgave, en sæt af guddommeligt etablerede normer og en række aktive valg
Antimicrobial Resistance and Whole Genome Sequencing Analysis of Neisseria gonorrhoeae Isolates in Bulgaria, 2019
Authors: Philipova Ivva , Levterova Viktoryia , Simeonovski Ivan , Kantardjiev Todor 
Published: November 2022

Neisseria gonorrhoeae is evolving into a superbug with resistance to previously and currently recommended antimicrobials for treatment of gonorrhoea, which creates a significant public health concern globally. Antimicrobial resistance (AMR) poses a great threat; it causes longer duration of illness and treatment, and increases health care costs and the social, psychological and financial burden to families and societies. In response to this worrying situation laboratory research should be strengthened with implementation of newer molecular methods for monitoring and detecting AMR, and evaluation of the correlation of obtained genetic data with corresponding phenotypes.
This study aimed to implement whole genome sequencing analysis for the first time of N. gonorrhoeae isolates from Bulgaria and to acquire molecular epidemiological and AMR information linked with phenotypic resistance data.
Although the tested strains were susceptible to current recommended dual therapy, genetic analysis showed the presence of several mutations responsible for reducing susceptibility to third generation cephalosporins, namely the presence of genotype G1407 strains in the Bulgarian population. Regarding previously recommended antimicrobials, penicillin resistance and intermediate sensitivity to tetracyclines was demonstrated in all strains, and fluoroquinolone resistance in two strains.
The obtained results showed that the use of whole genome sequencing was feasible, could describe current circulating gonococcal strains and predict and infer transmission of antimicrobial resistance. Therefore, gonococcal infections prevention and control programmes will be aided to target interventions where needed and to revise treatment guidelines that will help improve patient care.
Advantages of Real-time PCR and RD4-PCR as Molecular Methods for Rapid Detection of Bovine Tuberculosis in Bulgaria
Authors: Savova-Lalkovska Tanya , Valcheva Violeta , Dimitrova Albena , Najdenski Hristo , Bonovska Magdalena 
Published: November 2022

Representatives of Mycobacterium tuberculosis complex (MTBC) are potential causative agents of tuberculosis in animals and humans, and Mycobacterium bovis is considered a major one among domestic and wild ruminants. In the last twenty years, the role of another representative of MTBC – Mycobacterium caprae, has been proven in the countries of Central and Southern Europe. Study sample included 121 diagnostic materials from lymph nodes and lungs from cattle, positively and doubtfully PPD tuberculin-reacted, originating from 6 farms belonging to the 4 regions in Northern and Southern Bulgaria. The bacteriological examination showed typical growth for mycobacteria for 110 (90.9%) samples, which was confirmed by qPCR. By RD4-PCR we proved that 102 (92.7%) of the mycobacterial strains were M. caprae and the remaining 8 strains (7.3%) were M. bovis. This defines M. caprae as a dominant species in the etiology of tuberculosis in cattle in Bulgaria.
In conclusion, we confirmed that the application of real-time PCR is an accurate and convenient method for rapid detection of M. bovis from cattle in the Bulgarian settings. RD4-PCR provides a sufficiently high differentiation and can be used for first-line typing of M. bovis isolates in Bulgaria. This proves the need for the simultaneous application of both methods in the diagnosis of bovine tuberculosis in Bulgaria.
Urine-derived exosomes from individuals with IPF carry pro-fibrotic cargo
Authors: Elliot Sharon , Catanuto Paola , Pereira-simon Simone , Xia Xiaomei , Shahzeidi Shahriar , Roberts Evan , Ludlow John , Hamdan Suzana , Daunert Sylvia , Parra Jennifer , Stone Rivka , Pastar Irena , Tomic-Canic Marjana , Glassberg Marilyn K 
Published: November 2022

Background:MicroRNAs (miRNA) and other components contained in extracellular vesicles may reflect the presence of a disease. Lung tissue, sputum, and sera of individuals with idiopathic pulmonary fibrosis (IPF) show alterations in miRNA expression. We designed this study to test whether urine and/or tissue derived exosomal miRNAs from individuals with IPF carry cargo that can promote fibrosis.Methods:Exosomes were isolated from urine (U-IPFexo), lung tissue myofibroblasts (MF-IPFexo), serum from individuals with IPF (n=16) and age/sex-matched controls without lung disease (n=10). We analyzed microRNA expression of isolated exosomes and their in vivo bio-distribution. We investigated the effect on ex vivo skin wound healing and in in vivo mouse lung models.Results:U-IPFexo or MF-IPFexo expressed miR-let-7d, miR-29a-5p, miR-181b-3p and miR-199a-3p consistent with previous reports of miRNA expression obtained from lung tissue/sera from patients with IPF. In vivo bio-distribution experiments detected bioluminescent exosomes in the lung of normal C57Bl6 mice within 5 min after intravenous infusion, followed by distribution to other organs irrespective of exosome source. Exosomes labeled with gold nanoparticles and imaged by transmission electron microscopy were visualized in alveolar epithelial type I and type II cells. Treatment of human and mouse lung punches obtained from control, non-fibrotic lungs with either U-IPFexo or MF-IPFexo produced a fibrotic phenotype. A fibrotic phenotype was also induced in a human ex vivo skin model and in in vivo lung models.Conclusions:Our results provide evidence of a systemic feature of IPF whereby exosomes contain pro-fibrotic miRNAs when obtained from a fibrotic source and interfere with response to tissue injury as measured in skin and lung models.Funding:This work was supported in part by Lester and Sue Smith Foundation and The Samrick Family Foundation and NIH grants R21 AG060338 (SE and MKG), U01 DK119085 (IP, RS, MTC).
Segmentation of biventricle in cardiac cine MRI via nested capsule dense network
Authors: Zhang Jilong , Zhang Yajuan , Zhang Hongyang , Zhang Quan , Su Weihua , Guo Shijie , Wang Yuanquan 
Published: November 2022

Background
Cardiac magnetic resonance image (MRI) has been widely used in diagnosis of cardiovascular diseases because of its noninvasive nature and high image quality. The evaluation standard of physiological indexes in cardiac diagnosis is essentially the accuracy of segmentation of left ventricle (LV) and right ventricle (RV) in cardiac MRI. The traditional symmetric single codec network structure such as U-Net tends to expand the number of channels to make up for lost information that results in the network looking cumbersome.

Methods
Instead of a single codec, we propose a multiple codecs structure based on the FC-DenseNet (FCD) model and capsule convolution-capsule deconvolution, named Nested Capsule Dense Network (NCDN). NCDN uses multiple codecs to achieve multi-resolution, which makes it possible to save more spatial information and improve the robustness of the model.

Results
The proposed model is tested on three datasets that include the York University Cardiac MRI dataset, Automated Cardiac Diagnosis Challenge (ACDC-2017), and the local dataset. The results show that the proposed NCDN outperforms most methods. In particular, we achieved nearly the most advanced accuracy performance in the ACDC-2017 segmentation challenge. This means that our method is a reliable segmentation method, which is conducive to the application of deep learning-based segmentation methods in the field of medical image segmentation.
Genetic evolution of hemagglutinin and neuraminidase genes of H5N1 highly pathogenic avian influenza viruses in Thailand
Authors: Noisumdaeng Pirom , Phadungsombat Juthamas , Weerated Sasrinakarn , Wiriyarat Witthawat , Puthavathana Pilaipan 
Published: November 2022

Background
Ongoing outbreaks of H5N1 highly pathogenic avian influenza (HPAI) viruses and the emergence of the genetic-related hemagglutinin (HA) gene of reassortant H5Nx viruses currently circulating in wild birds and poultries pose a great global public health concern. In this study, we comprehensively analyzed the genetic evolution of Thai H5N1 HA and neuraminidase (NA) genes between 2003 and 2010. The H5N1 Thailand virus clade 2.3.4 was also genetically compared to the currently circulating clade 2.3.4.4 of H5Nx viruses.

Methods
Full-length nucleotide sequences of 178 HA and 143 NA genes of H5N1 viruses circulating between 2003 and 2010 were phylogenetically analyzed using maximum likelihood (ML) phylogenetic construction. Bayesian phylogenetic trees were reconstructed using BEAST analysis with a Bayesian Markov chain Monte Carlo (MCMC) approach. The maximum clade credibility (MCC) tree was determined, and the time of the most recent common ancestor (tMRCA) was estimated. The H5N1 HA nucleotide sequences of clade 2.3.4 Thailand viruses were phylogenetically analyzed using ML phylogenetic tree construction and analyzed for nucleotide similarities with various subtypes of reassortant H5Nx HA clade 2.3.4.4.

Results
ML phylogenetic analysis revealed two distinct HA clades, clade 1 and clade 2.3.4, and two distinct NA groups within the corresponding H5 clade 1 viruses. Bayesian phylogenetic reconstruction for molecular clock suggested that the Thai H5N1 HA and NA emerged in 2001.87 (95% HPD: 2001.34-2002.49) and 2002.38 (95% HPD: 2001.99-2002.82), respectively, suggesting that the virus existed before it was first reported in 2004. The Thai H5N1 HA clade 2.3.4 was grouped into corresponding clades 2.3.4, 2.3.4.1, 2.3.4.2, and 2.3.4.3, and shared nucleotide similarities to reassortant H5Nx clade 2.3.4.4 ranged from 92.4-96.8%. Phylogenetic analysis revealed monophyletic H5Nx clade 2.3.4.4 evolved from H5N1 clade 2.3.4.

Conclusion
H5N1 viruses existed, and were presumably introduced and circulated in avian species in Thailand, before they were officially reported in 2004. HA and NA genes continuously evolved during circulation between 2004 and 2010. This study provides a better understanding of genetic evolution with respect to molecular epidemiology. Monitoring and surveillance of emerging variants/reassortants should be continued.
Adult intussusception: a challenge to laparoscopic surgery?
Authors: Sun Mingze , Li Zhongmin , Shu Zhenbo , Wu Qi , Liu Xue 
Published: November 2022

Background
Intussusception can occur at any age and is common in children but less common in adults. This study aimed to evaluate our experience of 51 adult intussusception and study the etiology, clinical manifestations, diagnosis, and treatment.

Methods
This analysis assessed the clinical manifestations, etiology, diagnosis, and treatment of adult intussusception in 51 adult patients at the Department of Gastrointestinal Surgery of China-Japan Union Hospital of Jilin University from January 2010 to December 2020.

Results
The mean age of the cohort was 54.43 ± 18.21 years, and 42 patients were diagnosed by abdominal ultrasonography and abdominal computed tomography (CT). Among them, 76.5% (39/51) had abdominal pain, 11.8% (6/51) had blood in stool, and 5.9% (3/51) had a palpable abdominal mass. Of these, 62.7% had tumors: malignant accounted for 39.2% (20/51) and benign accounted for 23.5% (12/51). CT is the preferred imaging method with a sensitivity of 92.2%, while colonoscopy provides a complementary diagnosis in patients involving the colon. All patients underwent surgical treatment, including 21.6% (11/51) laparoscopic surgery, 74.5% (38/51) open surgery, and 5.9% (3/51) intussusception reduction during the operation. The average operation time of the open group was 133.27 ± 43.75 min and the average hospital stay was 16.24 ± 12.55 days, while the average operation time of the laparoscopic group was 140.50 ± 46.15 mins, and the average hospital stay was 16.60 ± 16.98 days (P > 0.05).

Conclusion
Adult intussusception is a rare disease in clinic. Laparoscopic surgery can be useful and safe for adult intussusception.
The Combination of Vivianite Powder and Compost Derived Poultry Litter: Appropriate Biological Fertilizer to Improve Nutritional Values of Carrot (Daucus Carota L.)
Authors: Hamadou Bachirou , Lucien Tchuenteu Tatchum , Abba Maimouna , Clautilde Megueni , Nicolas Njintang Yanou 
Published: November 2022

Aims: To improve the nutritional values of carrot in the Great North Cameroon by using natural fertilizing.
Study Design: A 11x2x2 factorial design with 11 origins of carrot roots (fertilizing) (T0, T+, P10, P15, Py10, Py15, F1, F1+P10, F1+P15, F1+Py10 and F1+Py15), 02 harvest areas (Maroua and Ngaoundere (Cameroon)) and 02 harvest years (2019 and 2020).
Place and Duration of Study: Laboratory of Biodiversity and Sustainable Development, University of Ngaoundere Cameroon, September 2019 and September 2020.
Methodology: Nutrient parameters of carrot roots (moisture, vitamin C, carotenoids, fiber, carbohydrates and ash of carrot roots contents) were assessed according to standard methods.
Results: Globally, carrot nutritional values varied significantly (p<0.05) depending on fertilizer, harvest area (Ngaoundere and Maroua Cameroon), and harvest year (2019 and 2020). The carrot nutrient contents from Maroua Cameroon were higher than those from Ngaoundere. The highest carrot nutrients content was from F1+P10 plots (combination of 1 Kg of poultry litter with 10 g of vivianite powder). In Maroua, roots from treated carrot plants with F1+P10 fertilizer are 1.55 and 1.24 fold richer in carotenoids than those from T0 and T+ plants respectively in 2019 ; in growing year 2020, the carotenoid contents of F1+P10 roots were 1.52 fold and 1.29 fold higher than those of T0 and T+ plants. In Ngaoundere, Vitamin C content of carrots from F1+P10 fertilizer is 1.79 fold higher than that of T0 plants and 1.18 fold higher than that of T+ plants in 2019, while in 2020 the value of this parameter was 1.69 fold and 1.47 fold higher than that of T0 and T+ plants respectively. The F1+P10 fertilizer encreased total carbohydrate content at 51.88 % compared to T0 and 20.03 % compared to T+ in Maroua, and at 27.59 % and 7.95 % compared to T0 and T+ respectively in Ngaoundere.
Conclusion: By used F1+P10 natural fertilizer for carrot growing, we contribute to improve the nutritional values of this vegetable crop, but also to valorize our local resources in biological agriculture, as well as to protect the environment.
Atomic‐Level Surface Engineering of Nickel Phosphide Nanoarrays for Efficient Electrocatalytic Water Splitting at Large Current Density
Authors: Lv Xinding , Wan Shutong , Mou Tianyou , Han Xue , Zhang Yifan , Wang Zilong , Tao Xia 
Published: November 2022

AbstractDesigning high‐performance and cost‐effective electrocatalysts for water splitting at high current density is pivotal for practical industrial applications. Herein, it is found that atomic‐level surface engineering of self‐supported nickel phosphide (NiP) nanoarrays via a facile cation‐exchange method can substantially regulate the chemical and physical properties of catalysts by introducing Co atoms. Such surface‐engineered NixCo1–xP endows several aspects of merits: i) rough nanosheet array electrode structure accessible to diffusion of electrolytes and release of gas bubbles, ii) enriched P vacancies companied by Co doping and thus increased active sites, and iii) the synergy of Ni5P4 and NiP2 beneficial to catalytic activity enhancement. By virtue of finely controlling the Co contents, the optimal Ni0.96Co0.04P electrode achieves remarkable bifunctional electrocatalytic performance for overall water splitting at a large current density of 1000 mA cm−2, showing overpotentials of 249.7 mV for hydrogen evolution reaction and 281.7 mV for oxygen evolution reaction. Furthermore, the Ni0.96Co0.04P electrode at 500 mA cm−2 exhibits an ultralow potential (1.71 V) and ultralong durability (500 h) for overall water splitting. This study implies that the atomic‐level surface engineering of the electrode materials offers a viable route for gaining high‐performance catalysts for water splitting at large current density.
Zwitterionic Polysaccharide‐Based Hydrogel Dressing as a Stem Cell Carrier to Accelerate Burn Wound Healing
Authors: Yu Qingyu , Sun Hong , Yue Zhiwei , Yu Chaojie , Jiang Lijie , Dong Xiaoru , Yao Mengmeng , Shi Mingyue , Liang Lei , Wan Yizao , Zhang Hong , Yao Fanglian , Li Junjie 
Published: November 2022

AbstractStem cell therapy integrated with hydrogels has shown promising potential in wound healing. However, the existing hydrogels usually cannot reach the desired therapeutic efficacy for burn wounds due to the inadaptability to wound shape and weak anti‐infection ability. Moreover, it is difficult to improve the environment for the survival and function of stem cells under complicated wound microenvironments. In this study, an injectable and self‐healing hydrogel (DSC), comprising sulfobetaine‐derived dextran and carboxymethyl chitosan, is fabricated through a Schiff‐base reaction. Meanwhile, the DSC hydrogel shows high nonfouling properties, including resistance to bacteria and nonspecific proteins; moreover, the prepared hydrogel can provide a biomimetic microenvironment for cell proliferation whilst maintaining the stemness of adipose‐derived stem cells (ADSCs) regardless of complex microenvironments. In burnt murine animal models, the ADSCs‐laden hydrogel can significantly accelerate wound healing rate and scarless skin tissue regeneration through multiple pathways. Specifically, the ADSCs‐laden DSC hydrogel can avoid immune system recognition and activation and thus reduce the inflammatory response. Moreover, the ADSCs‐laden DSC hydrogel can promote collagen deposition, angiogenesis, and enhance macrophage M2 polarization in the wound area. In summary, sulfobetaine‐derived polysaccharide hydrogel can serve as a versatile platform for stem cell delivery to promote burn wound healing.
Efficient Warming Textile Enhanced by a High‐Entropy Spectrally Selective Nanofilm with High Solar Absorption
Authors: He Cheng‐Yu , Zhao Peng , Zhang Hong , Chen Kai , Liu Bao‐Hua , Lu Zhong‐Wei , Li Yang , La Pei‐Qing , Liu Gang , Gao Xiang‐Hu 
Published: November 2022

AbstractSolar and radiative warming are smart approaches to maintaining the human body at a metabolically comfortable temperature in both indoor and outdoor scenarios. Nevertheless, existing warming textiles are ineffective in frigid climates because the solar absorption of selective absorbing coating is significantly reduced when coated on rough textile surface. Herein, for the first time, high‐entropy nitrides based spectrally selective film (SSF) is introduced on common cotton through a one‐step magnetron sputtering method. The well‐designed refractive index gradient enables destructive interference effects, offering a roughness‐insensitive high solar absorptance (92.8%) and low thermal emittance (39.2%). Impressively, the solar absorptance is 9.1% higher than the reported best‐performing selective nanofilm‐based textile. As a result, such a textile achieves a record‐high photothermal conversion efficiency (82.2% under 0.6 suns, at 0 °C). This textile yields a 3.5 °C drop in the set‐point of indoor air‐conditioner temperature. Besides, in a winter morning with an air temperature of 7.5 °C, it warms up the human skin by as large as 12 °C under weak sunlight (350 W m−2). More importantly, such a superior radiative warming performance is achieved by engineering the widely used cotton without compromising its breathability and durability, showing great potential for practical applications.
Nonclassical Growth of Atomically Flat Two‐Dimensional Organic Single Crystals on a Liquid Surface through Fusion
Authors: Yao Jiarong , Tian Xinzi , Li Bin , Wang Zhaofeng , Zhang Xiali , Jie Jiansheng , Yang Fangxu , Li Rongjin , Hu Wenping 
Published: November 2022

AbstractOrganic single crystals with low defect density are key functional materials for next‐generation electronics. Classical crystallization commonly results in a high density of molecular steps, which are defects that can trap charge carriers and reduce the mobility of organic semiconductors. Herein, a novel nonclassical crystallization mechanism involving nucleation, fusion, and growth is designed. The introduction of the fusion stage changes the crystal growth mode from three‐dimensional island growth to two‐dimensional layer‐by‐layer growth and leads to large‐area two‐dimensional molecular crystals with almost no molecular steps. Therefore, the average mobility is observed to improve from 1.26 to 2.07 cm2 V−1 s−1. The nonclassical crystallization mechanism paves the way for atomically flat single crystals to probe the intrinsic optoelectronic properties of organic semiconductors.