bluuebunny/crossref_metadata_2025_split huggingface dataset:
The position of financial prudence, social influence, and environmental satisfaction in the sustainable consumption behavioural model: Cross‐market intergenerational investigation during the Covid‐19 pandemic
Authors: Cui Yuting , Lissillour Raphael , Chebeň Juraj , Lančarič Drahoslav , Duan Chunlin 
Published: February 2022

AbstractThe main purpose of this study is to gain an in‐depth understanding of the impact of financial prudence (FIN) on social influence and environmental satisfaction in the sustainable consumption (SC) behavioural model from a cross‐market intergenerational perspective in the context of COVID‐19. Surprisingly, we discovered that, during the COVID‐19 pandemic, significant differences emerge between the Chinese and European markets in the four factors (social influence, SC behaviour, environmental satisfaction, and FIN). Unpredictably, Generation X in the European market and Generation Y in the Chinese market had the highest FIN during the pandemic. Another substantial contribution is that, during the epidemic, the influence of social interaction promotes SC behaviour and social influence motivates users to implement SC behaviours by enhancing environmental satisfaction. However, differences arise in the moderating effect of FIN. In China, the moderating effect occurs in the relationship between social influence and SC behaviour, whereas, in Europe, it reflects in the relationship between social influence and environmental satisfaction.
Alkylated glutamic acid and histidine derived from protein‐adducts indicate exposure to sulfur mustard in avian serum
Authors: John Harald , Hörmann Philipp , Schrader Michael , Thiermann Horst 
Published: February 2022

AbstractSulfur mustard (SM, bis[2‐chloroethyl]‐sulfide) is a banned chemical warfare agent deployed in the violent conflict in the Middle East poisoning humans and animals. For legal reasons, bioanalytical methods are mandatory proving exposure to SM. Reaction products (adducts) of SM with endogenous proteins, for example, serum albumin (SA), are valuable long‐lived targets for analysis. Whereas nearly all methods known so far focus on human proteins, we address for the first time neat chicken SA and avian serum from chicken, duck, and ostrich. After proteolysis, protein precipitation, evaporation of the supernatant, and re‐dissolution analysis were performed by micro‐liquid chromatography‐electrospray ionization tandem‐mass spectrometry in the selected reaction monitoring mode, μLC‐ESI MS/MS (SRM), for detection of the hydroxyethylthioethyl product ion [HETE]+ at m/z 105.0. After in vitro incubation with SM and pronase‐catalyzed proteolysis, the alkylated amino acids Glu(‐HETE) and His(‐HETE) were detected. Both borne the SM‐characteristic HETE‐moiety bound to their side chain. The eightfold deuterated SM analog (d8‐SM) was also applied to support adduct identification. Proteolysis conditions were optimized with respect to pH (8.0), temperature (50°C), and time to maximize the yield of Glu(‐HETE) (30 min) and His(‐HETE) (180 min). Amino acid adducts were stable in the autosampler for at least 24 h. Protein‐adducts were stable in serum at −30°C for at least 33 days and for three freeze‐and‐thaw cycles. At the body temperature of chicken (+40°C), Glu(‐HETE) was degraded in serum (period of half‐change 3 days), whereas His(‐HETE) remained stable. The presented method broadens the toolbox of procedures to document poisoning with SM.
Humpback whale adult females and calves balance acoustic contact with vocal crypsis during periods of increased separation
Authors: Indeck Katherine L. , Noad Michael J. , Dunlop Rebecca A. 
Published: February 2022

AbstractAcoustic communication is important for animals with dependent young, particularly when they are spatially separated. Maternal humpback whales (Megaptera novaeangliae) use acoustic calling to help minimize the risk of separation from their young calves during migration. These pairs also use acoustic crypsis to minimize detection by males. How they balance a restricted active space with the need to maintain acoustic contact during periods of separation is not yet understood. Here, we analyzed movement metrics of tagged adult female–calf pairs during migration to identify two behavioral states, “resting/milling” and “travelling.” When travelling, these pairs dived synchronously and exhibited little to no spatial separation. Alternatively, adult females had significantly longer dive durations (p < .01) when resting, and while they spent prolonged times at depth, calves would surface several times independently. This demonstrated that these pairs are frequently separated during periods of rest. We then determined whether the call rates and acoustic levels of these pairs increased with more frequent separation, finding that both adult females and calves significantly increased their call rates, but not levels, when resting. We also found that adult female–calf pairs have a restricted active space, with less than 15% of calls estimated to be detectable beyond 2 km. However, as with call level, detection distance did not differ significantly between the two behavioral states. In summary, adult female–calf pairs maintain successful communication during periods of separation by calling more frequently rather than by producing louder calls. This strategy aids in maintaining acoustic contact while simultaneously limiting detectability by conspecifics.
Constructing Ternary Photocatalyst Ag/Ni(OH)2/g‐C3N4 for Efficient Photocatalytic Hydrogen Production
Authors: He Ping , Deng Dashuang , Ren Tongyan , Dang Yinping , Li Ming , Chen Jiufu , Xiao Yao 
Published: February 2022

AbstractA series of ternary Ag/Ni(OH)2/g‐C3N4 composite photocatalysts were prepared by a facile method. The as‐prepared samples were characterized by powder X‐ray diffraction (XRD), Fourier transform infrared (FT‐IR), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and UV‐vis diffuse reflectance spectra (DRS). Photocatalytic water splitting for hydrogen was carried out to evaluate the photocatalytic performance of the as‐prepared samples and the effect of Ag and Ni(OH)2 content was explored. The results indicated that the A5N5−CN sample shows the optimal hydrogen evolution of 1663.2 μmol g−1 h−1, which was 114.7 times higher than that of bulk g‐C3N4. The enhanced photocatalytic activity can be ascribed to the synergistic effect of cocatalysts Ag and Ni(OH)2.
π‐Extendedperi‐Acenes: Recent Progress in Synthesis and Characterization
Authors: Ajayakumar M. R. , Ma Ji , Feng Xinliang 
Published: February 2022

AbstractNanographenes (NGs) with open‐shell character have gained intense attention due to their potential applications in future organic nanoelectronics and spintronics. Among them, NGs bearing a pair of parallel zigzag edges, such as acenes andperi‐acenes (PAs) bestow unique (opto)electronic and magnetic properties owing to their localized non‐bonding π‐state. However, their reactive zigzag edges impart intrinsic instability, leading to the challenging synthesis. The recent development of synthetic strategies provided access to several π‐extended PAs, which were considered unrealistic for decades. Notably, their laterally π‐extended structures of zigzag‐edged graphene nanoribbons was realised via on‐surface synthesis. However, synthesis of π‐extended PAs in solution is still in its infancy, more intensive scientific efforts are needed to surpass the existing challenges regarding stability and solubility. This Review provides an overview of recent progress in the synthesis and characterization of PAs through a bottom‐up synthetic strategy, including on‐surface and solution‐phase chemistry. In addition, views on existing challenges and the future prospects are also provided.
Electroacupuncture relieves neuropathic pain by inhibiting degradation of the ecto‐nucleotidase PAP in the dorsal root ganglions of CCI mice
Authors: Zhou Xiaoxin , Dai Wanbing , Qin Yi , Qi Siyi , Zhang Yizhe , Tian Weitian , Gu Xiyao , Zheng Beijie , Xiao Jie , Yu Weifeng , Chen Xuemei , Su Diansan 
Published: February 2022

AbstractBackgroundAlthough electroacupuncture is widely used in chronic pain management, it is quite controversial due to its unclear mechanism. We hypothesised that EA alleviates pain by inhibiting degradation of the ecto‐nucleotidase prostatic acid phosphatase (PAP) and facilitating ATP dephosphorylation in dorsal root ganglions (DRGs).MethodsWe applied EA in male C57 mice subjected to chronic constriction injury (CCI) and assessed extracellular ATP and 5′‐nucleotidease expression in DRGs. Specifically, we used a luminescence assay, quantitative reverse transcriptase–polymerase chain reaction, Western blotting, immunohistochemistry and nociceptive‐related behavioural changes to gather data, and we tested for effects after PAP expression was inhibited with an adeno‐associated virus (AAV). Moreover, membrane PAP degradation was investigated in cultured DRG neurons and the inhibitory effects of EA on this degradation were assessed using immunoprecipitation.ResultsEA treatment alleviated CCI surgery‐induced mechanical pain hypersensitivity. Furthermore, extracellular ATP decreased significantly in both the DRGs and dorsal horn of EA‐treated mice. PAP protein but not mRNA increased in L4–L5 DRGs, and inhibition of PAP expression via AAV microinjection reversed the analgesic effect of EA. Membrane PAP degradation occurred through a clathrin‐mediated endocytosis pathway in cultured DRG neurons; EA treatment inhibited the phosphorylation of adaptor protein complex 2, which subsequently reduced the endocytosis of membrane PAP.ConclusionsEA treatment alleviated peripheral nerve injury‐induced mechanical pain hypersensitivity in mice by inhibiting membrane PAP degradation via reduced endocytosis and subsequently promote ATP dephosphorylation in DRGs.SignificanceIn a mouse model of chronic pain, electroacupuncture treatment increased levels of prostatic acid phosphatase (PAP: an ecto‐nucleotidase known to relieve pain hypersensitivity) by inhibiting PAP degradation in dorsal root ganglions. This promoted extracellular ATP dephosphorylation, inhibited glia activation and eventually alleviated peripheral nerve injury‐induced mechanical pain hypersensitivity in mice. Our findings represent an important step forward in clarifying the mechanisms of pain relief afforded by acupuncture treatment.
Neurotoxicity‐associated sinus bradycardia after chimeric antigen receptor T‐cell therapy
Authors: Catalá Eva , Iacoboni Gloria , Vidal‐Jordana Ángela , Oristrell Gerard , Carpio Cecilia , Vilaseca Andreu , Cabirta Alba , Bosch Francesc , Tintoré Mar , Barba Pere 
Published: February 2022

AbstractThe advent of chimeric antigen receptor (CAR) T‐cell therapy has changed the therapeutic landscape of relapsed/refractory aggressive B‐cell lymphomas. Cytokine release syndrome and immune effector cell‐associated neurotoxicity syndrome (ICANS) are the typical adverse events associated with this therapy. Cardiovascular toxicities have also been reported in this setting. However, there is scarce data regarding the development of sinus bradycardia after CAR T‐cell therapy. Here, we detail the clinical course of 4 patients with aggressive B‐cell malignancies who received CAR T‐cells and developed transient and reversible sinus bradycardia in the context of ICANS. We also discuss several hypotheses behind the pathophysiology of this potential new adverse event.
Bioactive constituents from Mesona chinensis: Chemical evidence for its antihyperuricemic activity
Authors: Chen Chien‐Yi , Hsu Fu‐Chun , Tsai Sheng‐Fa , Lee Shoei‐Sheng 
Published: February 2022

AbstractMesona chinensis Benth. (Lamiaceae) has been shown antihyperuricemic effect in vivo. This study was aimed to provide chemical evidence for such bioactivity. Three new compounds (3, 4, and 8) together with 14 known were isolated from the n‐BuOH soluble fraction of its aerial part. All the structures were elucidated based on the spectroscopic analysis. This effort also revised the reported structure for mesonolate B. Except for 2 and 6, the remaining 15 isolates are reported for the first time from the title plant. Preliminary quantification of four majors (1, 5, 6, 8) by liquid chromatography–mass spectroscopy (LC–MS) (EIC) indicated their content in the dried aerial part to be 788, 146, 177, and 97 ppm (w/w), respectively. Among these isolates, 3‐O‐(6‐O‐feruloyl‐β‐d‐glucosyl)‐rosmarinic acid (3) was shown xanthine oxidase inhibition besides the reported rosmarinic acid (1), lithospermic acid A (5), isoquercitrin (11), and ursolic acid (13). In addition, compounds 2–4, 6 and 7, and 12 could be hydrolyzed to the corresponding active metabolites 1, 5, and 11 in the GI tract. Thus, this chemical investigation verified the reported hypouricemic effect of M. chinensis. Accordingly, this herbal medicine should have great potential to be developed as an antihyperuricemic nutraceutical.
Spatiotemporal dependency of resource use efficiency on phytoplankton diversity in Lake Taihu
Authors: Guo Chaoxuan , Zhu Mengyuan , Xu Hai , Zhang Yunlin , Qin Boqiang , Zhu Guangwei , Wang Jianjun 
Published: February 2022

AbstractThe dependency of resource use efficiency (RUE) on phytoplankton diversity is key for understanding aquatic ecosystem responses to eutrophication and climate change. Here, we studied RUE of nitrogen (RUEN), phosphorous (RUEP), or silicate (RUESi) and the associated abiotic and biotic explanatory variables in 3,016 samples collected from 30 sites in Lake Taihu during 2005‐2017, covering cyanobacteria‐ and macrophyte‐dominated regions. We further examined spatiotemporal dependencies of RUE on phytoplankton taxonomic and functional diversity and their underlying drivers. The annual mean RUEsi of each site exhibited an overall increasing temporal trend, while that of RUEN and RUEP displayed U‐shaped patterns over the study period. RUE was affected by nutrients and water temperature, and also was related to phytoplankton diversity in terms of Shannon diversity and functional dispersion diversity. Interestingly, RUE showed negative spatial dependencies on phytoplankton diversity. These negative spatial dependencies had decreasing temporal trends for RUEN and RUESi, while a hump‐shaped pattern for RUEP. The dependencies were generally related to spatial environmental mean of nutrients, such as nitrate and total phosphorus. Furthermore, RUE showed negative temporal dependencies on phytoplankton diversity mainly in the cyanobacteria‐dominated region, while it was occasionally positive in the macrophyte‐dominated region. These temporal dependencies were driven primarily by temporal environmental stability of nutrients, such as dissolved total nitrogen. Collectively, the direction and strength of spatiotemporal dependencies of RUE on phytoplankton diversity were influenced by nutrient status and stability. These findings can be considered in future environmental management plans for long‐term sustainability of ecosystem functioning under global climate change.
Technical note: A graphical approach to the analysis of travel times in an automated storage and retrieval system
Authors: Liu Jingming , Liao Haitao , White John A. 
Published: February 2022

AbstractOperating time is closely related to the performance of an order‐picking system. Knowing the probability distribution of operating time will greatly facilitate system performance analysis and optimization. When using an automated storage and retrieval system (AS/RS), travels of the storage and retrieval machine can be modeled using the Chebyshev metric. However, because of the dependence among the travel legs, analyzing the variance of travel time can be quite challenging. In this paper, a graphical approach based on contour lines is proposed for deriving the probability density function (PDF) of travel time in an AS/RS. With the PDF, the expected value and variance of travel time can be obtained. To demonstrate the use of the proposed approach in evaluating the performance of an AS/RS under stochastic conditions, we derive the PDF of travel time and apply it in a queueing analysis. Based on the queueing performance measures and an overall arrival rate, the minimum number of operation requests waiting or being served occurs when the arrival rates of storage and retrieval requests are approximately equal. Also, when arrival rates of storage and retrieval requests are equal, the number of operation requests waiting or being served is minimized when the rack is square‐in‐time.
An investigation of fear of recurrence, attachment and caregiving experiences among ovarian cancer partner‐caregivers
Authors: Petricone‐Westwood Danielle , Stragapede Elisa , Galica Jacqueline , Hales Sarah , Lebel Sophie 
Published: February 2022

AbstractObjectiveFear of cancer recurrence (FCR) is a common concern for both cancer patients and their caregivers. Attachment insecurity is an established contributor to poorer mental health, particularly as it relates to social support. This study sought to evaluate whether attachment and caregiver experiences in cancer care were predictors of FCR.MethodsA cross‐sectional questionnaire study involving partner‐caregivers of patients with ovarian cancer was conducted. Correlation analyses and multiple hierarchical regressions were used to determine the roles of attachment and caregiving experiences in cancer care on FCR, including the possible moderating role of attachment on the relationship between caregiving experiences and FCR.ResultsParticipants (n = 82), mostly identified as white men, had post‐secondary education and incomes of over $100,000 CAD, and cared for patients with advanced ovarian cancer. Forty percent of participants had clinically elevated FCR. Among the evaluated caregiving experiences in cancer care, caregiving workload (r = 0.33; p = 0.005), needing more help from healthcare providers (r = 0.28; p = 0.02), and lacking time for social relations because of caregiving (r = 0.47; p < 0.001) correlated with FCR. Attachment anxiety correlated significantly with FCR (r = 0.43; p < 0.001), but attachment avoidance did not. Attachment anxiety (ΔR2 = 0.14; p = 0.002) and lacking time for social relations (ΔR2 = 0.18; p < 0.001) contributed to the variance on FCR. Attachment insecurity did not moderate the relationships between caregiving experiences and FCR.ConclusionsPartner‐caregiver attachment anxiety correlates with FCR; however, this does not influence FCR's relationship with poorer perceived support from cancer care institutions. Partner‐caregivers may benefit from psychotherapies for FCR and more practical support from cancer care teams.
Solution structure and dynamics of the mitochondrial‐targeted GTPase‐activating protein (GAP) VopE by an integrated NMR/SAXS approach
Authors: Smith Kyle P. , Lee Woonghee , Tonelli Marco , Lee Yeongjoon , Light Samuel H. , Cornilescu Gabriel , Chakravarthy Srinivas 
Published: February 2022

AbstractThe bacterial pathogen Vibrio cholerae use a type III secretion system to inject effector proteins into a host cell. Recently, a putative Toxic GTPase Activating Protein (ToxGAP) called Vibrio outer protein E (VopE) was identified as a T3SS substrate and virulence factor that affected host mitochondrial dynamics and immune response. However, biophysical and structural characterization has been absent. Here, we describe solution NMR structure of the putative GTPase‐activating protein (GAP) domain (73–204) of VopE. Using size exclusion chromatography coupled with small‐angle x‐ray scattering and residual dipolar coupling data, we restrained the MD process to efficiently determine the overall fold and improve the quality of the output calculated structures. Comparing the structure of VopE with other ToxGAP's revealed a similar overall fold with several features unique to VopE. Specifically, the “Bulge 1,” α1 helix, and noteworthy “backside linker” elements on the N‐terminus are dissimilar to the other ToxGAP's. By using NMR relaxation dispersion experiments, we demonstrate that these regions undergo motions on a > 6 s−1 timescale. Based on the disposition of these mobile regions relative to the putative catalytic arginine residue, we hypothesize that the protein may undergo structural changes to bind cognate GTPases.
Cover Image, Volume 78, Issue 3
Authors: Bajda Sabina A , De Clercq Patrick , Van Leeuwen Thomas 
Published: February 2022

The cover image is based on the Research Article Selectivity and molecular stress responses to classical and botanical acaricides in the predatory mite Phytoseiulus persimilis Athias‐Henriot (Acari: Phytoseiidae) by Sabina A Bajda et al., https://doi.org/10.1002/ps.6747.image
Computational mechanisms affecting the efficiency of resource use in the honey bee swarm
Authors: Foss Richard A. 
Published: February 2022

AbstractThe honey bee swarm carried out its best‐of‐N nest site computations by operating more than a dozen different information processing loops in parallel and by recruiting more resources to provide greater precision in loops evaluating the better quality sites. The positive feedback effects of recurrent recruitment by means of waggle dance signalling amplified the utilisation of the swarm's energy, memory and carrier resources. The relatively strong negative feedback effects of various attenuation mechanisms tended to reduce resource use and therefore counter‐balanced amplification for long enough for a meaningful nest site survey and quorum decision to be made. Some information processing mechanisms such as exploration tendency, waggle dance signalling, site non‐specific attenuation, noise reduction, independent site evaluation, energy efficient coding, mixed precision processing, self‐organising computation and quorum decision making were found to profoundly influence the efficiency of resource use. Significant insights were also gained into extended cognition, dark data processing, information quality and resource leakage. Finally, the energy cost of acquiring and processing sensory information was estimated.
Recent Advancement of the Current Aspects of g‐C3N4for its Photocatalytic Applications in Sustainable Energy System
Authors: Hayat Asif , Sohail Muhammad , Ali Shah Syed Jawad , Al‐Sehemi Abdullah G. , Mohammed Mohammed H. , Al‐Ghamdi Ahmed A. , Taha T. A. , Salem AlSalem Huda , Alenad Asma M. , Amin Mohammed A. , Palamanit Arkom , Liu Changkun , Nawawi W. I. , Tariq Saeed Chani Muhammad , Muzibur Rahman Mohammed 
Published: February 2022

AbstractBeing one of the foremost enticing and intriguing innovations, heterogeneous photocatalysis has also been used to effectively gather, transform, and conserve sustainable sun‘s radiation for the production of efficient and clean fossil energy as well as a wide range of ecological implications. The generation of solar fuel‐based water splitting and CO2photoreduction is excellent for generating alternative resources and reducing global warming. Developing an inexpensive photocatalyst can effectively split water into hydrogen (H2), oxygen (O2) sources, and carbon dioxide (CO2) into fuel sources, which is a crucial problem in photocatalysis. The metal‐free g‐C3N4photocatalyst has a high solar fuel generation potential. This review covers the most recent advancements in g‐C3N4preparation, including innovative design concepts and new synthesis methods, and novel ideas for expanding the light absorption of pure g‐C3N4for photocatalytic application. Similarly, the main issue concerning research and prospects in photocatalysts based g‐C3N4was also discussed. The current dissertation provides an overview of comprehensive understanding of the exploitation of the extraordinary systemic and characteristics, as well as the fabrication processes and uses of g‐C3N4.