bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Femoral Component Cementation on Fracture and Mortality Risk in Elective Total Hip Arthroplasty
Authors: Edelstein Adam I. , Hume Eric L. , Pezzin Liliana E. , McGinley Emily L. , Dillingham Timothy R. 
Published: January 2022

Background:
Complications following elective total hip arthroplasty (THA) are rare but potentially devastating. The impact of femoral component cementation on the risk of periprosthetic femoral fractures and early perioperative death has not been studied in a nationally representative population in the United States.

Methods:
Elective primary THAs performed with or without cement among elderly patients were identified from Medicare claims from 2017 to 2018. We performed separate nested case-control analyses matched 1:2 on age, sex, race/ethnicity, comorbidities, payment model, census division of facility, and exposure time and compared fixation mode between (1) groups with and without 90-day periprosthetic femoral fracture and (2) groups with and without 30-day mortality.

Results:
A total of 118,675 THAs were included. The 90-day periprosthetic femoral fracture rate was 2.0%, and the 30-day mortality rate was 0.18%. Cases were successfully matched. The risk of periprosthetic femoral fracture was significantly lower among female patients with cement fixation compared with matched controls with cementless fixation (OR = 0.83; 95% CI, 0.69 to 1.00; p = 0.05); this finding was not evident among male patients (p = 0.94). In contrast, the 30-day mortality risk was higher among male patients with cement fixation compared with matched controls with cementless fixation (OR = 2.09; 95% CI, 1.12 to 3.87; p = 0.02). The association between cement usage and mortality among female patients almost reached significance (OR = 1.74; 95% CI, 0.98 to 3.11; p = 0.06).

Conclusions:
In elderly patients managed with THA, cemented stems were associated with lower rates of periprosthetic femoral fracture among female patients but not male patients. The association between cemented stems and higher rates of 30-day mortality was significant for male patients and almost reached significance for female patients, although the absolute rates of mortality were very low. For surgeons who can competently perform THA with cement, our data support the use of a cemented stem to avoid periprosthetic femoral fracture in elderly female patients.

Level of Evidence:
Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
Design of Optimal Real Time Emulators for Steam and Wind Turbines for Avoiding Risky Severe Conditions
Authors: El-Zoghby helmy , Ramadan Haitham S. , Alhelou Hassan Haes 
Published: January 2022

Abstract
Modern energy infrastructures may face critical impacts on distributed generation and microgrids in presence of renewable and conventional energy sources. Fast restorations for these networks through proposing convenient proactive protection systems become mandatory for securing energy particularly after severe faults. This paper deals with presenting a descriptive modelling and comprehensive analysis of both steam and wind turbines using optimal real time emulators with unique testbench. Based on the dynamics of each turbine, both emulators are performed using 4kW, 180V, 1500r.p.m separately exited DC motor coupled to 2kW, 380V, 50Hz, 1500r.p.m three-phase synchronous generator. For real-time interface implementation, the mathematical models of steam and wind turbines are realized using LabVIEWTM software. The characterization and verification of both emulated steam and wind turbines are examined at different normal operating conditions in terms of steam valve position and wind speed, respectively. To regulate the current for both systems despite their diverse dynamics, a simple industrial proportional-integral (PI) controller is considered. Unlike other artificial intelligence-based controllers, the offline-controller gains are scheduled using genetic algorithm (GA) via MatlabTM software to ensure the due fast response to cope with unexpected faults. The experimental validity of both emulators is tested at the most severe abnormal operating conditions. The three-phase short circuit is considered at the generator terminals with different fault periods until reaching out-of-step conditions. From numerical analysis and experimental results, the characterization of both emulated steam and wind turbines explicitly mimics their real large-scale turbines in normal conditions. The emulators’ fast responses using the proposed GA-PI control approach are verified. Besides, the experimental dynamic behavior convergence and interoperability between the emulated and real systems for both steam and wind turbines are validated under severe conditions. The practical results confirm the fast-nature performance of the GA in avoid risky instability conditions.
Effect of Integrating Maternal and Child Health Services, Nutrition and Family Planning Services on Postpartum Family Planning Uptake at 6 Months Post-partum in Burkina Faso, Cote d’Ivoire and Niger: Protocol of a Longitudinal Quasi-experimental Study
Authors: KPEBO DENISE , Coulibaly Abou , Yameogo Maurice , Bijou Sujata , Ramatoulaye Lazoumar , Tougri Halima , N’dour Marguerite , Kouanda Seni 
Published: January 2022

Abstract
Background : Although several interventions integrating maternal, neonatal, child health and nutrition with family planning have been implemented and tested, there is still limited evidence on their effectiveness to guide program efforts and policy action,on health services integration. This study aims to assess the effectiveness of a service delivery model integrating maternal and child health services, nutrition and family planning services, compared with the general standard of care in Burkina Faso, Cote d'Ivoire, and Niger. Methods: This is a quasi experimental study with one intervention group and one control group of 3-4 health facilities in each country. Each facility was matched to a control facility of the same level of care and that had similar coverage on selected reproductive health indicators such as family planning and post-partum family planning. The study participants are pregnant women (with a 6 months pregnancy at maximum) coming for their first antenatal care visit. They will be followed up to 6 months after childbirth, and will be interviewed at each antenatal visit and also during visits for infant vaccines.The analyzes will be carried out by intention to treat, using generalized linear models (binomial log or log Poisson) to assess the effect of the intervention on the ratio of contraceptive use prevalence between the two groups of the study at a significance level of 5%, while taking into account the cluster effect and adjusting for potential confounding factors (socio-demographic characteristics of women, unevenly distributed at inclusion). Discussion :This longitudinal study, with the provision of family planning services integrated into the whole maternal care continuum, a sufficiently long observation time and repeated measurements, will make it possible to better appreciate the timeline and the factors influencing women's decision-making on the use of post-partum family planning services. The results will help in increasing the body of knowledge regarding the impact of maternal and child health services integration on the utilization of post-partum family planning, taking into account the specific context of sub-Saharan Africa French speaking countries where such information is very needed.
Application of Nature Inspired Soft Computing Techniques for Gene Selection: A Novel Frame Work for Classification of Cancer.
Authors: Aziz Rabia Musheer 
Published: January 2022

Abstract
A modified Artificial Bee Colony (ABC) metaheuristics optimization technique is applied for cancer classification, that reduces the classifier's prediction errors and allows for faster convergence by selecting informative genes. Cuckoo search (CS) algorithm was used in the onlooker bee phase (exploitation phase)of ABC to boost performance by maintaining the balance between exploration and exploitation of ABC. Tuned the modified ABC algorithm by using Naïve Bayes (NB) classifiers to improve the further accuracy of the model. Independent Component Analysis (ICA) is used for dimensionality reduction. In the first step, the reduced dataset is optimized by using Modified ABC and after that, in the second step, the optimized dataset is used to train the NB classifier. Extensive experiments were performed for comprehensive comparative analysis of the proposed algorithm with well-known metaheuristic algorithms, namely Genetic Algorithm (GA) when used with the same framework for the classification of six high-dimensional cancer datasets. The comparison results showed that the proposed model with the CS algorithm achieves the highest performance as maximum classification accuracy with less count of selected genes. This shows the effectiveness of the proposed algorithm which is validated using ANOVA for cancer classification.
Beliefs in Misinformation and Conspiracy Theories About COVID- 19: a Triangular Relationship Between Analytic Thinking, Depressive States, and Misperception
Authors: Delmastro Marco , Paciello Marinella 
Published: January 2022

Abstract
Beliefs about misinformation and conspiracy theories are often associated with a state of mind. With the spread of the pandemic there has been an outbreak of depression cases among the population. In this paper, we attempt to test the relationship between affective states and beliefs in misinformation about COVID-19 during the early phase of the pandemic. We do this through a survey carried out on a random and representative sample of the Italian population that allows us to go and verify the co-evolution of many factors: i.e., beliefs in misinformation, symptoms of depression, perceptions and misperceptions about COVID-19, ways in which citizens got informed about the pandemic, and sociodemographic characteristics (e.g., age, gender, education). The results show that the relationship between affective state and beliefs in misinformation exists but is more complex than hypothesized.
The Electronic Waste Management Crisis- A Situation Analysis of Zambia
Authors: NALWAMBA DAIZY SHOMA 
Published: January 2022

Abstract
Globally, the technological era has seemingly increased the environmental burden of many Low income countries in the management of electronic waste. An increase in the use of electrical and electronic equipment potentially relates to an increase in e-waste in the environment. Poorly managed ewaste degrades the environment in various ways such as through percolation of toxicants into the soils and leaching into aquatic systems. As Zambia steadily develops, the use of EEEs is a major threat in the increased amounts of e-waste thus placing more demand on environmental institutions as well as wellestablished and sustainable e-waste management systems. Environmental issues are complex and diverse, in this view; waste management is an integral part of a sustainable environment thus making effective electronic waste management categorically fundamental. This study employed a mixed method approach (concurrent nested) to assess the effectiveness of electronic waste management facilities in Lusaka. In this study, the inclusion and exclusion criteria were used so as to select the participants by use of questionnaires and interviews. This study showed that in Zambia, e-waste has not been given the same attention as other waste types. The knowledge base of electrical and electronic equipment users is very shallow as this study indicated that most EEE consumers have little or no knowledge of the toxic components of electronic waste. Further, available environmental institutions do not currently have the capacity to quantify e-waste that is generated in the country. Moreover, the e-waste that is appropriately disposed of is exported to neighboring countries recycling. The study concluded that Zambia lacks the needed expertise and facilities to adequately handle e-waste. However, information obtained from EEE users and e-waste generators clearly indicated that inasmuch as there could be efforts by environmental institutions to manage e-waste, there hasn’t been local authority effort to specifically handle e-waste or rather sensitize the users of EEEs on e-waste issues. The study thus recommended the following; creation of e-waste black market, further Studies, Laws to prohibit dumping of e-waste, Promotion of E-waste education amongst EEE users, Promotion of E-waste education amongst EEE users, Repurpose old devices before purchasing new ones.
Biocompatibility Evaluation of PEO-treated Magnesium Alloy Implants Placed in Rabbit Femur Condyle Notches and Paravertebral Muscles
Authors: Kim Seong Ryoung , Lee Keon Mo , Kim Jin Hong , Choi Young Jin , Park Han Ick , Jung Hwa Chul , Roh Hyung Jin , Han Jee Hye Lo , Kim Joon Rae , Lee Bu-Kyu 
Published: January 2022

Abstract
Background: Magnesium alloys have been receiving much attention for use in biodegradable metal implants because of their excellent mechanical properties and biocompatibility. However, their rapid breakdown and low bioactivity can cause the implant to lose mechanical integrity before the bone is completely healed. Moreover, hydrogen gas released during degradation can significantly delay the tissue regeneration process. To solve the instability of magnesium alloys, Zn and Ca can be added to improve the mechanical properties and biocompatibility. One other way to improve the mechanical properties of Mg is plasma electrolytic oxidation (PEO), which provides a dense, thick ceramic-like coating on the Mg surface. In this study, high-purity Mg was selected as the control, and Mg-1wt%Zn-0.1wt%Ca alloy and PEO-treated Mg-1wt%Zn-0.1wt%Ca alloy were selected as the test materials; the results of radiographic and histological analyses of their biocompatibility are reported herein. Materials and method: Nineteen New Zealand white rabbits were used in the study. Rod-bars (Ø2.7x13.6mm) were placed on both paravertebral muscles, and cannulated screws (Ø2.7x10mm) were placed on both femur condyle notches. Each animal was implanted in all four sites. X-rays were taken at 0, 2, 4, 8, and 12 weeks, micro-CT, and live-CT were taken at 4, 8, and 12 weeks. At weeks 4, 8, and 12, individuals representing each group were selected and sacrificed to prepare specimens for histopathological examination. Result: The results confirm that in vivo, Mg-1wt%Zn-0.1wt%Ca alloy had higher corrosion resistance than high-purity Mg and safely degraded over time without causing possible side effects (foreign body or inflammatory reactions, etc.). In addition, PEO treatment of Mg-1wt%Zn-0.1wt%Ca alloy had a positive effect on fracture recovery by increasing the bonding area with bone. Conclusion: Our results suggest that PEO treatment of Mg-1wt%Zn-0.1wt%Ca alloy can be a promising biomaterials in the field of various clinical situations such as orthopedic and maxillofacial surgerys.
Modified Tectonic Corneoscleral Graft For Management of Devastating Corneoscleral Infections
Authors: Zhang Xiaoyu , Qi Xiaolin , Wang Miaolin , Gao Hua 
Published: January 2022

Abstract
Purpose To analyze the clinical results and the efficacy of modified tectonic corneoscleral graft (TCG) in patients with devastating corneoscleral infections.Methods Twenty-five eyes from 25 patients who underwent modified TCG were enrolled. The recurrence, best-corrected visual acuity (BCVA), ocular surface stability, postoperative complications and graft survival condition were recorded.Results Among 25 patients, 19 cases were fungal infection and 6 cases were bacterial. The rate of recurrence was 8% with Pythium Insidiosum as a corresponding pathogen. The rate of monocular blindness declined from 100% to 57%. Changes in BCVA from preoperative to postoperative values were significant ( Z=4.22, P＜0.001). The survival of ocular surface stability was 73.6% and 43.9% at 1 and 3 years after surgery, respectively. Within the mean follow-up period of 17.5 ± 8.9 months, 21eyes (84.0%) had a stable ocular surface. The incidence rate of immune rejection was 36%. Corneal epithelial defects occurred in 7 patients and choroidal detachment occurred in 3 patients. No elevation of intraocular pressure was detected.Conclusions The modified TCG is effective in eradicating infection, salvaging the eyeball and saving some useful vision for devastating corneoscleral infections. Regular application of tacrolimus, timely addition of glucocorticoid and good compliance may decrease the postoperative course challenging.
Reasonable Layout of High Drainage Roadways for Jiaojiazhai Mine
Authors: Hu Dongjie , Li Zongxiang 
Published: January 2022

Abstract
To ensure that the gas concentration at the top corner does not exceed the limit, a reasonable level of the high drainage roadway layout in Jiaojiazhai Mine should be determined. In this work, based on the actual conditions of the working face, an SF6 tracer gas was used to test the connectivity between the high drainage roadway and the working face. A discrete element analysis program was used to simulate the deformation law of the overlying strata in the goaf, and a corresponding caving control program for the surrounding rock was written based on the obtained parameters and “O” ring theory. A fluid simulation software was used to simulate and analyze five goaf models with different high drainage roadway layouts (10, 15, 20, 25, and 30 m). The gas drainage data for two layers (10 m and 20 m) of the high drainage roadway were measured. The results showed that the height of the caving zone in the goaf is approximately 20 m, and when the high drainage roadway is arranged along the roof (when the layout layer height is 10 m), the roadway will be directly connected to the working face, thus pumping fresh air to the working face. The gas extraction effect of the 20 m stratum was better than those of the other strata. The simulation results of the gas extraction were consistent with the measured data. The proposed scheme was practically applied, and its effect was found to be evident, thus solving the problem of high gas concentration at the top corner and increasing the mine output.
A Novel Coq8a Mutation in a Case with Juvenile Onset Coq10d4: Case Report and Literature Review
Authors: Dedeoglu Özge , Tükün Ajlan , Laleli Yahya 
Published: January 2022

Abstract
Primary coenzyme Q10 deficiency-4 (COQ10D4) is an autosomal recessive disorder characterized by childhood-onset of cerebellar ataxia and exercise intolerance. Molecular pathology responsible for clinical findings is mitochondrial respiratory chain dysfunction. The main clinical manifestation involves early onset exercise intolerance, progressive cerebellar ataxia and movement disorders. Some affected individuals develop seizures and have mild mental impairment, indicating variable severity. COQ8A gene mutations are responsible for this disease. Here we present a patient with tremor and cerebellar atrophy in which we detected a new mutation in the COQ8A gene. The patient's clinical findings were compatible with juvenile onset COQ10D4. Therefore, we reviewed the clinical, laboratory and genetic findings of 11 juvenile-onset COQ10D4 patients reported to date, as well as the patient's presentation.
Candidate microRNA Biomarkers in Lupus Nephritis: A Meta-Analysis of Profiling Studies in Kidney, Blood and Urine Samples
Authors: Roointan Amir , Gholaminejad Alieh , Shojaie Behrokh , Hudkins Kelly , Gheisari Yousof 
Published: January 2022

Abstract
Lupus nephritis (LN) is a kidney disease caused by systemic lupus erythematosus in which kidneys are attacked by the immune system. MiRNAs participate in the pathogenesis of LN as modulatory effectors in immune responses and nephrogenesis pathways. Despite the large number of miRNAs that are expressed deferentially, identifying the most suitable biomarker candidate for LN is challenging. The aim of this study was to introduce a consensus panel of potential miRNA biomarkers by performing a meta-analysis of miRNA profiles in the kidney, blood, and urine samples of LN patients. A comprehensive literature review approach was considered to find LN-related miRNA expression profiles. After including the 41 eligible studies and performing the data extraction, meta-analysis was done based on the vote-counting rank strategy and as well as meta-analysis of p-value. The result of the meta-analysis was three lists of consensus miRNAs with altered expression profiles in the various tissue samples of LN patients. Of the 13 studies on kidney tissue, the meta-miRNAs were let-7a, miR-198, let-7e, miR-145, and miR-26a. In addition, meta-miRNAs of miR-199a, miR-21, miR-423, miR-1260b, miR-589, miR-150, miR-155, miR-146a, and miR-183 from 21 studies on blood samples, and miR-146a, miR-204, miR-30c, miR-3201, and miR-1273e from 11 studies on urine samples can be considered as non-invasive biomarker panels for LN. The meta-miRNAs and their related genes were subjected to functional enrichment analyses and network construction. Functional enrichment analysis confirmed the involvement of their target genes in nephropathy-related signaling pathways. Network construction showed miR-145-5p in blood and miR-155-5p in kidney, the best hob miRNAs as candidate drug targets. In conclusion using a meta-analysis approach, our study proposes three meta-miRNA panels that could be the target of further research to assess their potential as biomarkers / therapeutic targets in LN disease.
Assessment of Quality of Ground Water Body of Neelangarai and Triplicane Area in Chennai, Tamil Nadu in The Post Inundation Circumstances
Authors: Rajendran A , Mansiya C. , Shanmuganathan M. 
Published: January 2022

Abstract
Although flood hit the entire part of Chennai, Tamil nadu some three years ago, the quality of water is still found to be worse because of major inundation in these areas. The current inspection deals with the physico-chemical analysis of the ground water samples collected from ten locations in Neelangarai and Triplicane area in Chennai, Tamil Nadu and assessed using Heber Water Quality Index (HWQI) in the post tsunami circumstances. The factors examined were pH, fecal coliform, total dissolved solids (TDS), dissolved oxygen (DO), temperature biochemical oxygen demand (BOD) and turbidity. In addition to these parameters, pointers like electrical conductivity and salinity were also taken into consideration. The over all HWQI outcomes for all the trials in Neelangarai area were determined between 65.02 and 72.25 and Triplicane area was 66.64 - 70.71, which suggest that all the samples are medium to good in quality and could used for human consumption.