bluuebunny/crossref_metadata_2025_split huggingface dataset:
Digitizing UK analogue magnetogram records from large geomagnetic storms of the past two centuries
Authors: Beggan Ciaran D. , Eaton Eliot , Maume Eleanor , Clarke Ellen , Williamson John , Humphries Thomas 
Published: March 2022

AbstractContinuous geomagnetic records of the strength and direction of the Earth's field at the surface extend back to the 1840s. Over the past two centuries, eight observatories have existed in the United Kingdom, which measured the daily field variations using light‐sensitive photographic paper to produce analogue magnetograms. Around 350,000 magnetograms have been digitally photographed at high resolution. However, converting the traces to digital values is difficult and time consuming as the magnetograms can have over‐lapping lines, low quality recordings and obscure metadata for conversion to SI units. We discuss our approach to digitizing the traces from large geomagnetic storms and highlight some of the issues to be aware of when capturing magnetic information from analogue measurements. These include cross‐checking the final digitized values with the recorded hourly mean values from observatory year books and comparing several observatory records for the same storm to catch errors such as sign inversions or incorrect ‘wrap‐around’ of data on the paper records.
High‐resolution simulated water balance and streamflow data set for 1951–2020 for the territory of Poland
Authors: Marcinkowski Paweł , Kardel Ignacy , Płaczkowska Eliza , Giełczewski Marek , Osuch Paweł , Okruszko Tomasz , Venegas‐Cordero Nelson , Ignar Stefan , Piniewski Mikołaj 
Published: March 2022

AbstractLong‐term simulated water balance and streamflow data for the territory of Poland with high spatio‐temporal resolution were reconstructed for the period 1951–2020 with a daily time step, using the Soil and Water Assessment Tool (SWAT) hydrological model. The spatial structure includes 4,381 sub‐basins and 47,725 hydrological response units. The SWAT model was extensively calibrated and validated following a two‐stage, multi‐site calibration method for 88 gauging stations across Poland. The simulations show satisfactory performance with a median Kling–Gupta efficiency of 0.73 and 0.7 in the calibration and validation period respectively. The model performance exceeded that of its predecessor, the SWAT model of the Vistula and Odra basins. The simulated hydrological data set covers daily water balance components at the sub‐basin level, including precipitation total, snowfall, snowmelt, evapotranspiration (actual and potential), surface runoff, soil water, percolation, groundwater recharge, groundwater flow, tile flow and water yield (all components in mm), and daily streamflow (m3/s) at the reach level. The data set is stored in an online, publicly available research data archive 4TU.Research Data (Marcinkowski, P., Kardel, I., Płaczkowska, E., Giełczewski, M., Osuch, P., Okruszko, T., Venegas‐Cordero, N., Ignar, S. & Piniewski, M (2021). PL‐SWAT‐51_20: a high‐resolution simulated water balance and streamflow data set for 1951‐2020 for the territory of Poland, 4TU.ResearchData. dataset, https://doi.org/10.4121/16843183).
HLA‐matched allogeneic anti‐CD19 CAR‐T therapy in treating a relapsed/refractory acute lymphoblastic leukemia patient with high tumor burden
Authors: Huang Yue , Yu Qin , Yin Elaine Tan Su , Wei Guoqing , Wu Wenjun , Chang Alex H. , Huang He , Hu Yongxian 
Published: March 2022

AbstractThe genetically engineered chimeric antigen receptor T cell (CAR‐T) therapy has shown remarkable clinical efficacy in the treatment of hematological malignancies. Nonetheless, it is difficult to harvest adequate autologous T cells to manufacture potent CAR‐T cell products in patients with high tumor burden and prior tumor‐reductive treatment. Here we reported a relapsed/refractory acute lymphoblastic leukemia patient with high leukemia burden and central nervous system (CNS) involvement. The patient responded to donor‐derived HLA‐matched allogeneic CAR‐T treatment, with the achievement of quick complete remission. And for the first time, we revealed the development of a cerebral CRS in situ after allogeneic CAR‐T therapy.
Embodied philanthropy and Sir Captain Tom Moore's “Walk for the NHS”
Authors: Wade Matthew , Hookway Nicholas , Filo Kevin , Palmer Catherine 
Published: March 2022

AbstractRecent decades have witnessed growing popularity in embodied philanthropy, where participants undertake various types of publicly displayed bodily labour in support of their respective causes. The fundraising potential of such efforts reached extraordinary heights during Sir Captain Thomas Moore's “Walk for the National Health Service,” wherein the 99‐year‐old World War II veteran walked laps of his garden to raise funds during the COVID‐19 pandemic. Within less than a month “Captain Tom” raised over £30 million, the highest amount ever by an individual charity walker. To better understand the social and cultural drivers behind Moore's incredible popularity this article applies Julie Robert's theoretical framework of embodied philanthropy, exploring the multivalent semiotic potential that Moore radiated through his age, disability, military adornments, Yorkshire grit, and unfailingly positive, aphoristic style of speaking. During a time of global crisis, this distinct array of bodily affordances enabled Captain Tom to simultaneously serve as an honest broker, teacher, exemplar, rallying figure, and ultimately martyr. Such practices of sacrificial citizenship, however, raise troubling questions, particularly in relation to expectations that fellow citizens should likewise stoically uphold civic‐minded resilience during times of crisis. Furthermore, while the potential benefits can prove extraordinarily impactful, organizations should exercise care in too readily attaching themselves to particular causes, lest they become complicit in contentious agendas or even inadvertently mislead donors.
Evaluating the dynamic‐mechanical and thermal stability of polyphenylene sulfide composites filled with magnetic filler for sensor applications
Authors: Aloui Sahbi , El Yaagoubi Mohammed , Münster Bernhard , Schwegler Dietmar 
Published: March 2022

AbstractIsotropic polyphenylene sulfide (PPS) composites filled with the magnetic fillers strontium ferrites (SrFeO) and neodymium iron boron (NdFeB) at two concentrations of 52 vol.% and 60 vol.% were prepared by the injection molding technique without use of an external magnetic field. Frequency sweeps shows that the mechanical frequency has little influence on the strength of all PPS samples and only ensures a higher mobility of the PPS chain ends at high frequency. Increasing the magnetic filler content and the use of NdFeB instead of SrFeO provide the PPS composites a larger structural robustness making them more resistant to mechanical loads and mechanically more stable. The temperature behavior of the PPS composites shows independently of the filler a strong softening from 80 °C. Nevertheless, larger operating temperatures below the glass transition temperature appear realistic.
Gas‐phase experimental and computational studies of human hypoxanthine‐guanine phosphoribosyltransferase substrates: Intrinsic properties and biological implications
Authors: Zhang Lanxin , Hinz Damon J. , Kiruba George Sebastina Mary , Ding Xiao , Lee Jeehiun K. 
Published: March 2022

AbstractThe gas‐phase acidity and proton affinity of nucleobases that are substrates for the enzyme human hypoxanthine‐guanine phosphoribosyltransferase (HGPRT) have been examined using both theoretical and experimental methods. These thermochemical values have not heretofore been measured and provide experimental data to benchmark the computational results. HGPRT is important for human health and is also a key target for antiparasitic chemotherapy. We use our gas‐phase results to lend insight into the HGPRT mechanism and also propose kinetic isotope studies that could potentially differentiate between possible mechanisms.
Direct C−H Functionalization of Calix[n](het)arenes (n=4,6): A Brief Update
Authors: Mukherjee Anindita , Kopchuk Dmitry S. , Kovalev Igor S. , Santra Sougata , Varaksin Mikhail V. , Zyryanov Grigory V. , Majee Adinath , Chupakhin Oleg N. , Charushin Valery N. 
Published: March 2022

AbstractCalix[4]arenes are, probably, the mostly explored macrocycles in the supramolecular chemistry. By means of the synthetic modification/functionalization of the upper or lower rims, as well as meso‐positions, the “host‐guest” properties of these macrocycles can be modulated in order to accommodate the guest molecules of various sizes and nature for supramolecular and coordination chemistry, and to perform various functions for materials science and for biomedical applications. In this review, we wish to highlight the most prospective synthetic approaches for the direct C−H functionalization of calixarene core with various functional moieties. Depending on the nature of the functional moiety these calix[4]arenes can serve as drug carriers and nano‐containers for the recognition, encapsulation or storage of bioactive molecules and for many other applications. Current review article deals with the recent examples of C(H)‐functionalization of calix[4]arenes, as well as selected patterns of direct C(H)‐modification of some calix[6]arenes and calix[4]pyrroles.
Study on the Luminescence and Coordination Behavior of Semi‐rigid Dual‐Benzimidazole Ligands and Complexes
Authors: Jia Qiangqiang , Feng Kangkang , Tong Liang , Wang Guoxi X. , Chen Lizhuang Z. 
Published: March 2022

AbstractIn this work, two novel semi‐rigid bisbenzimidazole ligands with different substituents (L1,2‐H; L2,2H‐methyl; L3, 2H‐ethyl; L4, 2H‐isopropyl; L5, 2H‐tertbutyl, which L1‐L3 have been reported,[19,20]to compare the effects of different substituents on properties, herein, we re‐synthesize them) and two coordination compounds are synthesized. Single crystal structure X‐ray diffraction data suggests that the ligand(L1) exhibits boat‐like configuration in the crystal lattice which makes the compound 1 crystallizes in the polar space group (C2), otherwise, chair‐like structure of ligands (L2‐L4) makes compound 2–4 grow in centrosymmetric space group (C2/c). Interestingly, polar compound 1 demonstrates typical ferroelectric behavior with remnant electric polarization (Pr) of 0.308 μC/cm2 and an electric coercive field (Ec) of 20 kV/cm. In addition, the fluorescence of the compounds 1–4 all are in the blue‐violet light region under the combined action of metal ions and organic ligands. Notably, L5 emits bright charming orange light at 365 nm UV light, and we also verified the reason and possibility of luminescence through density functional theory (DFT) calculations. Besides, the photoluminescence quantum yield (PLQY) of the L5 is up to 24.6 % and fluorescence lifetime is 3.29 ns. In short, this work might provide strategy to construct metal organic frameworks (MOFs) with ferroelectric and photoluminescent properties.
Patient satisfaction and incidence of adverse events during a trial of sonographer administered musculoskeletal injections
Authors: Osborne Brooke , Thoirs Kerry , Dizon Janine , Parange Nayana , Milanese Steve 
Published: March 2022

AbstractIntroductionIncreases in demand for therapeutic ultrasound‐guided musculoskeletal injections have led to longer waiting times for appointments. With the right training, sonographers are well placed to perform these low‐risk procedures. This study evaluated the effect of musculoskeletal injections administered by trained sonographers with respect to patient safety and satisfaction.MethodsPatients were recruited from three radiology clinics staffed with appropriately trained sonographers. Patients who agreed to have their injection completed by a sonographer completed satisfaction surveys immediately after their appointment, with adverse reactions also recorded. Longer‐term outcomes were recorded 7–10 days later.Results97% of 804 participating patients were completely satisfied with the service they received. Reported adverse events were low, with <1% and 8% immediately and at follow up respectively. There was demonstrated patient satisfaction with staff and the service, and support for the importance of this service in reducing the extensive waiting times experienced.ConclusionThis study indicates that appropriately trained sonographers can provide ultrasound‐guided musculoskeletal injections at a level of safety which is comparable to similar injection procedures explored in the literature. The high level of satisfaction of the patients suggest that this service should be extended and expanded to address patient concerns regarding long waiting times.
Dynamic governance of the first wave of Covid‐19 in Tunisia: An interoperability analysis
Authors: Nasri Khaled , Boubaker Houda , Dhaouadi Nacef 
Published: March 2022

AbstractThis study proposes an interoperability index of the measures taken by the Tunisian government during the first wave of the coronavirus disease 2019 (COVID‐19) pandemic. In the first part, we present the process of decision making as a revised and adjusted process in continuous upgrading, based on the dynamic governance process in times of crisis. In the second part, we estimate an index that records the strictness of government policies in each subperiod and the degree of interoperability between the Tunisian pandemic responses against COVID‐19 using subperiod instantiations. Our empirical findings show that the pandemic management strategy in Tunisia during the first wave was adjusted by incorporating new pandemic policies and changing the stringency levels over time. After estimating the interoperability index, we found that the measures taken early in a subperiod interact directly with the next successive subperiod in the decision process, but they interact indirectly with other successive subperiods.
τRR minimization in presence of hypermultiplets
Authors: Amariti Antonio , Gnecchi Alessandra 
Published: March 2022

Abstract
We compute τRR minimization in gauged supergravity for M-theory and String Theory truncations with both massless and massive vector multiplets. We explicitly compute, as anticipated in [1], that massive vector fields at the vacuum require the introduction of a constraint through a Lagrange multiplier. We illustrate this explicitly in two examples, namely the U(1)2-invariant truncation dual to the mABJM model and the ISO(7) truncation in massive IIA, the latter being a theory with both electric and magnetic gauging. We revisit the vacuum constraints at AdS4 and show how the supergravity analysis matches the results of the field theory dual computation.
Gender influence on clinical manifestations, depressive symptoms and brain-derived neurotrophic factor (BDNF) serum levels in patients affected by fibromyalgia
Authors: Iannuccelli Cristina , Lucchino Bruno , Gioia Chiara , Dolcini Giulio , Rabasco Jole , Venditto Teresa , Ioppolo Francesco , Santilli Valter , Conti Fabrizio , Di Franco Manuela 
Published: March 2022

Abstract
Introduction

Objectives
Fibromyalgia (FM) is a common rheumatic disorder characterized by chronic, widespread pain associated with several not painful symptoms. The contribution of gender to the manifestation of the disease may influence the higher prevalence of FM among women. In spite of this, how patients’ gender influences the clinical manifestation of FM is still not well understood. The frequent association with neuropsychiatric symptoms raised the attention on the role of neurotrophins, including the brain-derived neurotrophic factor (BDNF) as potential biomarkers of the condition. Aims of the study were to evaluate the influence of gender on clinical manifestations and to investigate BDNF serum levels as a potential biomarker of FM.

Methods
We consecutively enrolled 201 adult patients of both sexes diagnosed with FM. For each patient, we collected clinical and clinimetric data and, in a subgroup of 40 patients, we measured serum BDNF levels. BDNF levels have been measured also in 40 matched healthy controls (HC).

Results
Several symptoms were significantly higher in women compared with men, including pain, fatigue, memory problems, tenderness, balance problems and sensitivity to environmental stimuli. On the contrary, men reported a significant higher frequency of coexisting depressive symptoms. BDNF levels were significantly lower in FM patients compared with HC, discriminating with good accuracy the condition.

Conclusion
Gender influences FM clinical manifestations, with a higher prevalence of pain, fatigue and other common FM symptoms among women while higher frequency of neuropsychiatric symptoms among men. BDNF offers promises as a potential biomarker of the disease.

Key Points• Gender-related differences in the clinical manifestations of FM may contribute to the higher prevalence of FM among females. Indeed, women show higher levels of pain and symptoms traditionally associated to FM, which are evaluated to establish the diagnosis according to the clinical criteria.• The new insights into the pathogenesis of the disease raised the attention on the role of brain mediators in FM. Among these, BNDF shows potential as a diagnostic biomarker.
On the analyticity of the abstract MGT-Fourier system
Authors: Dell’Oro Filippo , Pata Vittorino 
Published: March 2022

AbstractWe consider the abstract MGT-Fourier system $${\left\{ \begin{array}{ll} u_{ttt}+\alpha u_{tt}+\beta A^\varrho u_t+\gamma A^\varrho u = \eta A \theta \\ \theta _t+\kappa A \theta = -\eta A u_{tt} - \eta \alpha A u_t \end{array}\right. }$$

u

ttt

+
α

u

tt

+
β

A
ϱ

u
t

+
γ

A
ϱ

u
=
η
A
θ

θ
t

+
κ
A
θ
=
-
η
A

u

tt

-
η
α
A

u
t

in the subcritical regime $$\beta >\gamma /\alpha$$

β
>
γ
/
α

, where the operator A is strictly positive selfadjoint. For any fixed $$\varrho \in [1,2]$$

ϱ
∈
[
1
,
2
]

, we show that the associated solution semigroup S(t) is analytic and exponentially stable as well.
Visual plagiarism in interior design: is it easy to recognise?
Authors: Bettaieb Donia M. , Alawad Abeer A. , Malek Raif B. 
Published: March 2022

AbstractThis study aims to remove some of the ambiguities of visual plagiarism in interior design (those related to the visual composition of space represented by line, form, shape, texture, time, colour, light, etc.) by examining the main detection methods, the extent of the issue, and the experiences and roles of academic interior designers. Two main methods were used: an analysis of the primary forms of visual plagiarism and an applied approach to test the effectiveness of plagiarism. Additionally, 30 academics in the Kingdom of Saudi Arabia, who majored in interior design, were surveyed using an online questionnaire. The results demonstrated that changing the light and colour while maintaining the rest of the properties and changing the line, form, and shape are considered visual plagiarism. However, the results also indicated that visual plagiarism is not always clear for academics. It is hoped that the results of this study will increase the awareness of visual plagiarism, enhance ethics in the university environment, and help academic interior designers apply scientific methods to detect plagiarism in design projects. This study can also assist regulatory authorities to manage complaints and disputes in plagiarism cases.
Distribution of labor, productivity and innovation in collaborative science
Authors: Gargiulo Floriana , Castaldo Maria , Venturini Tommaso , Frasca Paolo 
Published: March 2022

AbstractIn this paper, we investigate the process of scientific discovery using an under-exploited source of information: the Polymath projects. Polymath projects are an original attempt to solve a series mathematical problems collectively and in a collaborative online environment. To investigate the Polymath experiment, we analyze all the posts related to the projects that have resulted in a peer-reviewed publication. We focus in particular on the organization of the scientific labor and on the innovations that result from the contributions of the different authors. We find that a high presence of occasional contributors increases the productivity of the most active users and the overall productivity of the forums (i.e., the number of posts grows super-linearly with the number of contributors). We argue that, in large-scale collaborations, the serendipitous interaction between occasional contributors can be crucial to the scientific process, and individual contributions from occasional participants can open new directions of research.
Investigation of a nonlinear piezoelectric energy harvester with advanced electric circuits with the finite element method
Authors: Hegendörfer Andreas , Steinmann Paul , Mergheim Julia 
Published: March 2022

Abstract
In this contribution, a system simulation method based on the finite element method (FEM) is applied to simulate a strongly coupled bimorph piezoelectric vibration-based energy harvester (PVEH) with various nonlinear, non-ideal and active circuits: The standard circuit, the synchronized switch harvesting on inductor circuit and the synchronized electric charge extraction circuit are considered. Furthermore, nonlinear elastic behavior of the piezoelectric material is taken into account and harmonic base excitations of different magnitudes at a fixed frequency are applied. The holistic FEM-based system simulation approach solves the complete set of piezoelectric equations together with the equation of the electric circuit such that all electromechanical coupling phenomena are taken into account. This fully coupled numerical analysis enables the detailed evaluation of the influences of the electric circuits on the vibrational behavior and the harvested energy of the PVEH with respect to the magnitude of base excitation. Results from literature on the efficiency of electric circuits are confirmed and interactions between mechanical and electrical nonlinearities of PVEHs are revealed.

Article highlights

System simulations of a mechanically and electrically nonlinear piezoelectric energy harvester are performed using only one software tool.

The infuence of electric circuits on the vibration behavior and the effciency of an energy harvester are investigated in detail.

Interactions between mechanical and electrical nonlinearities of an energy harvester are revealed.
Nutritional, antioxidant, carbohydrate hydrolyzing enzyme inhibitory activities, and glyceamic index of wheat bread as influence by bambara groundnut substitution
Authors: Oguntuase Samuel Oladeji , Ijarotimi Oluwole Steve , Oluwajuyitan Timilehin David , Oboh Ganiyu 
Published: March 2022

AbstractThe research was designed to ascertain the potential of bambara groundnut inclusion in wheat bread to improve antioxidant activity, modulate carbohydrate hydrolyzing enzyme activities, and lower glyceamic index/ load. Protein (g/100 g) (11.2—11.73) and energy value (kcal/100 g) (421.5—435.5) of the bread were significantly higher than commercial wheat flour bread (CWF—10.45; 388.7). However, developed experimental bread samples exhibited higher growth performance in rats, free radical scavenging potentials, inhibitory activities against carbohydrate hydrolyzing enzymes and low glycemic index than other bread samples. Nevertheless, experimental bread samples were rated lower compared with the controls samples as regards organoleptic properties. The study authenticates that WBO3—25% wheat, and 75% bamabara groundnut WBO3 exhibits higher potentials as regards nutritional composition, growth indices, free radical scavenging potentials, ability to modulate carbohydrate hydrolyzing enzyme and lower glycemic index/ load. Hence, WBO3 may be recommended as functional bread for hyperglycemia prevention/ management.