bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ethiopian women’s sexual experiences and coping strategies for sexual problems after gynaecological cancer treatment: a qualitative study
Authors: Hundie Gashaw Yada , Sendo Endalew G , Habte Teshome 
Published: March 2022

ObjectiveThis study explored women’s sexual experiences and coping strategies for sexual problems after gynaecological treatment.SettingThe research was carried out at Tikur Anbessa Specialized Hospital, one of the two cancer centre hospitals in the country.Study designA phenomenological qualitative study design was employed in this study.Study participantsParticipants were recruited using purposeful sampling. Thirteen eligible study participants were interviewed face to face. Data were collected from 2 February to 15 March 2019 and analysed at the same time. For data analysis, thematic analysis was used, which comprises three stages: data reduction, data display and data conclusion.ResultsFour themes resulted from the analysis of individual interview data, including treatment side effects, sexual issues following radiation therapy, lack of awareness regarding cancer treatment and sexual dysfunction, and coping strategies for sexual dysfunction following gynaecological cancer treatment. Three subthemes emerged as coping mechanisms for managing sexual issues and dysfunction among Ethiopian women with gynaecological cancer: avoiding sexual intercourse, praying for healing and seeking professional help. These themes were identified as the rich and detailed account of the experiences of sexually active women who have received treatment for their cervical cancer.ConclusionThis study has broadened the perspectives on sexuality in the setting of gynaecological cancer and challenged certain commonly held beliefs about sexuality after treatment. Researchers should look into how inclusive sexuality education and training may be better integrated into the training programmes of healthcare workers. More research is needed to learn how partners of women with gynaecological cancer cope with sexual changes after treatment, how the couple as a partnership negotiates changes after treatment, and the facilitators and barriers that healthcare providers face when discussing sexuality issues with patients.
Qualitative study exploring factors affecting the implementation of a vocational rehabilitation intervention in the UK major trauma pathway
Authors: Kettlewell Jade , Radford Kate , Kendrick Denise , Patel Priya , Bridger Kay , Kellezi Blerina , Das Nair Roshan , Jones Trevor , Timmons Stephen 
Published: March 2022

ObjectivesThis study aimed to: (1) understand the context for delivering a trauma vocational rehabilitation (VR) intervention; (2) identify potential barriers and enablers to the implementation of a VR intervention post-trauma.DesignQualitative study. Data were collected in person or via phone using different methods: 38 semistructured interviews, 11 informal ‘walk-through care pathways’ interviews, 5 focus groups (n=25), 5 codesign workshops (n=43). Data were thematically analysed using the framework approach, informed by the Consolidated Framework for Implementation Research.SettingStakeholders recruited across five UK major trauma networks.ParticipantsA variety of stakeholders were recruited (n=117) including trauma survivors, rehabilitation physicians, therapists, psychologists, trauma coordinators and general practitioners. We recruited 32 service users (trauma survivors or carers) and 85 service providers.ResultsThere were several issues associated with implementing a trauma VR intervention including: culture within healthcare/employing organisations; extent to which healthcare systems were networked with other organisations; poor transition between different organisations; failure to recognise VR as a priority; external policies and funding. Some barriers were typical implementation issues (eg, funding, policies, openness to change). This study further highlighted the challenges associated with implementing a complex intervention like VR (eg, inadequate networking/communication, poor service provision, perceived VR priority). Our intervention was developed to overcome these barriers through adapting a therapist training package, and by providing early contact with patient/employer, a psychological component alongside occupational therapy, case coordination/central point of contact, and support crossing sector boundaries (eg, between health/employment/welfare).ConclusionsFindings informed the implementation of our VR intervention within the complex trauma pathway. Although we understand how to embed it within this context, the success of its implementation needs to be measured as part of a process evaluation in a future trial.
Role of adherent and invasiveEscherichia coliin Crohn’s disease: lessons from the postoperative recurrence model
Authors: Buisson Anthony , Sokol Harry , Hammoudi Nassim , nancey Stéphane , Treton Xavier , Nachury Maria , Fumery Mathurin , Hébuterne Xavier , Rodrigues Michael , Hugot Jean-Pierre , Boschetti Gilles , Stefanescu Carmen , Wils Pauline , Seksik Philippe , Le Bourhis Lionel , Bezault Madeleine , Sauvanet Pierre , Pereira Bruno , Allez Matthieu , Barnich Nicolas 
Published: March 2022

ObjectiveWe used the postoperative recurrence model to better understand the role of adherent and invasiveEscherichia coli(AIEC) bacteria in Crohn’s disease (CD), taking advantage of a well-characterised postoperative cohort.DesignFrom a prospective, multicentre cohort of operated patients with CD, AIEC identification was performed within the surgical specimen (M0) (N=181 patients) and the neoterminal ileum (n=119 patients/181) during colonoscopy performed 6 months after surgery (M6). Endoscopic postoperative recurrence was graded using Rutgeerts’ index. The mucosa-associated microbiota was analysed by 16S sequencing at M0 and M6. Relative risks or ORs were adjusted on potential confounders.ResultsAIEC prevalence was twofold higher within the neoterminal ileum at M6 (30.3%) than within the surgical specimen (14.9%) (p<0.001). AIEC within the neoterminal ileum at M6 was associated with higher rate of early ileal lesions (i1) (41.6% vs 17.1%; aRR 3.49 (95% CI 1.01 to 12.04), p=0.048) or ileal lesions (i2b+i3) (38.2% vs 17.1%; aRR 3.45 (95% CI 1.06 to 11.30), p=0.040) compared with no lesion (i0). AIEC within the surgical specimen was predictive of higher risk of i2b-endoscopic postoperative recurrence (POR) (aOR 2.54 (95% CI 1.01 to 6.44), p=0.049) and severe endoscopic POR (aOR 3.36 (95% CI 1.25 to 9.06), p=0.017). While only 5.0% (6/119) of the patients were AIEC-positive at both M0 and M6, 43.7% (52/119), patients with history of positive test for AIEC (M0 or M6) had higher risk of ileal endoscopic POR (aOR 2.32 (95% CI 1.01 to 5.39), p=0.048)), i2b-endoscopic postoperative recurrence (aOR 2.41 (95% CI 1.01 to 5.74); p=0.048) and severe endoscopic postoperative (aOR=3.84 (95% CI 1.32 to 11.18), p=0.013). AIEC colonisation was associated with a specific microbiota signature including increased abundance ofRuminococcus gnavus.ConclusionBased on the postoperative recurrence model, our data support the idea that AIEC are involved in the early steps of ileal CD.Trial registration numberNCT03458195.
Effects of a Pilates programme in spinal curvatures and hamstring extensibility in adolescents with thoracic hyperkyphosis: a randomised controlled trial
Authors: González-Gálvez Noelia , Marcos-Pardo Pablo Jorge , Albaladejo-Saura Mario , López-Vivancos Abraham , Vaquero-Cristóbal Raquel 
Published: March 2022

AbstractAimTo evaluate the effects of a 9-month Pilates exercise programme on the sagittal spinal posture and hamstring extensibility of adolescents with thoracic hyperkyphosis.DesignRandomised controlled trial with blinded examiner.PatientsOne-hundred and three adolescents with thoracic hyperkyphosis.InterventionsParticipants were randomly placed into an experimental group which participated in a Pilates exercise programme implemented for a total of 38 weeks (two sessions/week, 15 min/session) (Pilates group (PG), sample = 49, or control group (CG), sample = 48).Main outcome measuresThe outcome measures were the thoracic curve in sagittal spinal curvature in relaxed standing, sagittal spinal curvatures and pelvic tilt in relaxed standing and sit-and-reach positions, and hamstring extensibility.ResultsThere was a significant adjusted mean difference between groups in favour of the PG in the thoracic curve in relaxed standing position (−5.6°, p = 0.003), pelvic tilt (−2.9°, p = 0.03) and all straight leg tests (p&lt;0.001). The PG showed a significant change in thoracic curve (−5.9, p&lt;0.001) and in lumbar angle (4.0, p = 0.001) in relaxed standing position and in all straight leg raise tests (+6.4 to +15°, p&lt;0.0001).ConclusionsThe adolescents with thoracic hyperkyphosis from the PG had a decreased thoracic kyphosis in relaxed standing position, and improved hamstring extensibility as compared with the CG. More than 50% of the participants obtained kyphosis values inside normality, showing an adjusted mean difference between groups in the thoracic curve of about 73% of the baseline mean, resulting in a large improvement and high clinical importance.Trial registration numberNCT03831867.
Short-term exposure to ambient air pollution and individual emergency department visits for COVID-19: a case-crossover study in Canada
Authors: Lavigne Eric , Ryti Niilo , Gasparrini Antonio , Sera Francesco , Weichenthal Scott , Chen Hong , To Teresa , Evans Greg J , Sun Liu , Dheri Aman , Lemogo Lionnel , Kotchi Serge Olivier , Stieb Dave 
Published: March 2022

BackgroundAmbient air pollution is thought to contribute to increased risk of COVID-19, but the evidence is controversial.ObjectiveTo evaluate the associations between short-term variations in outdoor concentrations of ambient air pollution and COVID-19 emergency department (ED) visits.MethodsWe conducted a case-crossover study of 78 255 COVID-19 ED visits in Alberta and Ontario, Canada between 1 March 2020 and 31 March 2021. Daily air pollution data (ie, fine particulate matter with diameter less than 2.5 µm (PM2.5), nitrogen dioxide (NO2) and ozone were assigned to individual case of COVID-19 in 10 km × 10 km grid resolution. Conditional logistic regression was used to estimate associations between air pollution and ED visits for COVID-19.ResultsCumulative ambient exposure over 0–3 days to PM2.5 (OR 1.010; 95% CI 1.004 to 1.015, per 6.2 µg/m3) and NO2(OR 1.021; 95% CI 1.015 to 1.028, per 7.7 ppb) concentrations were associated with ED visits for COVID-19. We found that the association between PM2.5and COVID-19 ED visits was stronger among those hospitalised following an ED visit, as a measure of disease severity, (OR 1.023; 95% CI 1.015 to 1.031) compared with those not hospitalised (OR 0.992; 95% CI 0.980 to 1.004) (p value for effect modification=0.04).ConclusionsWe found associations between short-term exposure to ambient air pollutants and COVID-19 ED visits. Exposure to air pollution may also lead to more severe COVID-19 disease.
A single dose of dietary nitrate supplementation protects against endothelial ischemia–reperfusion injury in early postmenopausal women
Authors: Somani Y.B. , Soares R.N. , Gosalia J. , Delgado J.M. , Flanagan M. , Basu S. , Kim-Shapiro D.B. , Murias J.M. , Proctor D.N. 
Published: March 2022

The onset of menopause and accompanying changes to ovarian hormones often precedes endothelial dysfunction in women. In particular, accelerated impairments in macrovascular and microvascular function coincide with the loss of estrogen, as does impaired endothelial responses to ischemia–reperfusion (IR) injury. In healthy, early postmenopausal women ( n = 12; 3.9 ± 1.5 years since menopause) we tested the hypothesis that acute dietary nitrate (NO3−) supplementation would improve endothelial function and attenuate the magnitude of endothelial dysfunction following whole-arm IR in comparison with placebo. In this randomized, double-blind, placebo-controlled, crossover study we tested participants before and after NO3−-rich (BRnitrate) and NO3−-depleted (BRplacebo) beetroot juice (BR) consumption, as well as following IR injury, and 15 min after IR to assess recovery. Analyses with repeated-measures general linear models revealed a condition × time interaction for brachial artery flow-mediated dilation (FMD; P = 0.04), and no interaction effect was found for the near-infrared spectroscopy-derived reperfusion slope ( P = 0.86). Follow-up analysis showed a significant decline in FMD following IR injury with BRplacebo in comparison with all other timepoints (all, P < 0.05), while this decline was not present with BRnitrate (all, P > 0.05). Our findings demonstrate that a single dose of dietary NO3− minimizes IR-induced macrovascular endothelial dysfunction in healthy, early postmenopausal women, but does not improve resting macrovascular and microvascular function. Trial registration number: NCT03644472. Novelty: In healthy, early postmenopausal women, a single dose of NO3−-rich BR can protect against IR-induced endothelial dysfunction. This protection may be due to nitric oxide bioactivity during IR rather than improved endothelial function prior to the IR protocol per se.
Northwest Atlantic redfish science priorities for managing an enigmatic species complex
Authors: Cadigan Noel G. , Duplisea D.E. , Senay C. , Parent G.J. , Winger P.D. , Linton B. , Kristinsson K. 
Published: March 2022

Redfish ( Sebastes spp.) in the Northwest Atlantic (NWA) extend from Baffin Island in the north to the Gulf of Maine in the south. The two most abundant species are Sebastes mentella and Sebastes fasciatus, which are morphometrically similar and difficult to visually distinguish. Redfish are long-lived, slow-growing, late-maturing, tend to produce large year classes episodically, and have complex population structure. Intraspecific genetic groups are abundant in the NWA. They are often semipelagic and patchily distributed, which makes them difficult to survey. These are all characteristics that cause difficulties for stock assessment and for sustainable fisheries management. This was the focus of The Ocean Frontier Institute Northwest Atlantic Redfish Symposium in 2018. In this paper, we synthesize the information known about NWA redfish. To improve the scientific basis for sustainable harvest strategies, key research recommendations involve (1) improved biological sampling including species and ecotype; (2) developing integrated stock assessment models; (3) developing harvest strategies with management reference points that are appropriate for redfish; (4) improving fishing technology and practices to avoid capture of small nonmarketable redfish and other species.
Multi-body modelling and adaptive control of a re-configurable uninhabited airship
Authors: Tuta-Navajas Gilmar , Lanteigne Eric 
Published: March 2022

This paper presents pitch control of an uninhabited airship using changes in center of gravity. Changes in center of gravity are achieved by controlling the position of a movable gondola along a rigid keel fixed to the bow of the helium envelope. The longitudinal multi-body dynamic equations of motion were developed using the measured and estimated physical properties and an adaptive PID controller was designed to control the pitch angle. Flight tests on a 4 m long uninhabited airship prototype were conducted to demonstrate the effectiveness of the method.
Replicated Computational Results (RCR) Report for “A New Test for Hamming-Weight Dependencies”
Authors: Wu Xiaoliang , Jin Dong 
Published: March 2022

In the paper “A New Test for Hamming-Weight Dependencies”, Blackman and Vigna propose a new statistical test for
pseudorandom number generators (PRNG)
. Compared with the state-of-the-art tests, the proposed test could find statistical bias in the Hamming weights of the output of the generator. The proposed test is evaluated by using generators in TestU01 [
2
]. The authors provide the C code used in the tests and the code successfully reproduced the results shown in the article.
Effect of Respiration Training-Assisted Western Medicine Therapy on Activity Tolerance, Pulmonary Function, and Quality of Life of Chronic Obstructive Pulmonary Disease Patients in the Stable Phase
Authors: Tong Yaqi , Cui Jia , Chai Di 
Published: March 2022

Objective. To explore the effect of respiration training-assisted western medicine therapy on activity tolerance, pulmonary function, and quality of life (QOL) of chronic obstructive pulmonary disease (COPD) patients in the stable phase. Methods. The medical data of 90 COPD patients in the stable phase treated in the respiratory medicine of our hospital (November 2020–November 2021) were chosen for the retrospective analysis, and the patients were split into group A (n = 45, respiration training-assisted western medicine therapy) and group B (n = 45, western medicine therapy) according to the clinical reception order, so as to record and compare the activity tolerance, lung function, and QOL between the groups after intervention. Results. Compared with group B after intervention, group A showed greatly longer mean 6-min walking distance, significantly lower St. George’s Respiratory Questionnaire (SGRQ) score, significantly higher specific airway conductance (sGAW) and level values of various lung function indicators, and significantly lower level values of airway resistance (RAW) and specific airway resistance (sRAW) (

p

all<0.001); the total effective rate was significantly higher in group A (

p

< 0.05). Conclusion. Respiration training-assisted western medicine therapy is a dependable way to improve the activity tolerance of COPD patients in the stable phase, and such strategy largely improves patients’ lung function and QOL. Deeper studies will be helpful to establish a preferable solution for such patients.
Serum Carotenoids and Cancer-Related Fatigue: An Analysis of the 2005–2006 National Health and Nutrition Examination Survey
Authors: Kleckner Amber S. , van Wijngaarden Edwin , Jusko Todd A. , Kleckner Ian R. , Lin Po-Ju , Mustian Karen M. , Peppone Luke J. 
Published: March 2022

Cancer-related fatigue is a prevalent, debilitating condition, and preliminary evidence suggests a relationship between higher diet quality and lower fatigue. Serum-based carotenoids, Vitamin A, and Vitamin E are biomarkers of fruit and vegetable intake and therefore diet quality. To further elucidate the link between diet quality and cancer-related fatigue, associations were assessed between these serum-based nutrients and fatigue among American adults with special attention to cancer history. Data were analyzed from the United States 2005–2006 National Health and Nutrition Examination Survey dataset. Ten carotenoids, vitamin A, vitamin E, and γ-tocopherol were measured from fasting blood samples and fatigue was patient-reported. Associations between carotenoid concentration and fatigue were estimated using ordinal logistic regression models. Adjusted models included a diagnosis of cancer (with the exception on nonmelanoma skin cancer, yes/no), age, body mass index, race/ethnicity, education, and exercise habits as covariates, and additional models included a cancer × nutrient interaction. Of 4,091 participants, 272 (8.0%) reported a history of cancer. Greater fatigue was associated with lower serum trans-lycopene, retinyl palmitate, and retinyl stearate (all P &lt; 0.05) in separate models adjusting for potential confounders. For these nutrients, a one-SD increase in nutrient was associated with a 6.8%–9.9% lower risk of greater fatigue. Among cancer survivors only (n = 272), statistically significant associations were not observed between any of the nutrients and fatigue. In conclusion, greater serum concentrations of carotenoid biomarkers were associated with less fatigue. These results support further exploration into relationships between carotenoid intake, diet quality, and persistent fatigue.Significance:Cancer-related fatigue often persists for years into survivorship, reduces quality of life, and prevents people from returning to their lives before cancer. Interventions to address cancer-related fatigue are much needed. Herein, serum carotenoids were associated with lower fatigue, thereby supporting further development of nutritional interventions to address fatigue in survivorship.
The Evaluation of Exam Preparation for Reading Skills by Indonesian Daf-Teachers
Authors: Ardiyani Dewi Kartika , Rofiáh Rofiáh 
Published: March 2022

The minimum competency assessment (Asesmen Kompetensi Minimum / AKM) is an assessment of the basic competencies of Indonesian learners. The AKM consists of test questions that are created by teachers. Self-competence and critical thinking of the learner are to be emphasized by these test questions. The AKM instrument comprises two basic skills, namely reading skills and mathematical skills (numeric). The aim of this study is to find out the difficulty of Indonesian German teachers in preparing for reading competence exams and to describe the AKM test questions for learning German at high school (SMA / MA) in Indonesia. This study used a descriptive-qualitative method with questionnaire as the data collection technique. The data is Indonesian German teachers (20 teachers) difficulty in reading exam preparation and the AKM test questions they had been created. Based on the data result of the questionnaire, it is found that most teachers have had difficulty creating questions about the content of the text that encourage critical thinking of the learners. In addition, the validation results of the AKM test questions show that the text selection should be adapted to the goals to be achieved. The tasks related to the text should be able to improve the productive skills of the learner, e.g. graphic form. The selected text should contain a lot of information and the answer options should not be so easy to choose. The results of this research are intended to provide information for Indonesian German teachers so that they can create AKM test questions that encourage critical thinking skills of the learners. This can then develop the learner's reading skills.