bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rosai Dorfman disease- A rare entity: Case report in North Indian male
Authors: Ankur Baruah  , Parul Goyal  , K. L. Ramesh  
Published: January 2025

Rosai Dorfman disease is a rare disease characterized by histiocytic proliferation of lymph node in young adults. We present here the case of a 67 years old Indian male presenting with lymphadenopathy and pyrexia of unknown origin for 16 months duration. Histopathological examination of lymph nodes revealed emperipolesis consistent with the diagnosis of Rosai Dorfman disease. The patient recovered with steroid treatment .Our case is one of the few cases of adult onset Rosai Dorfman Disease reported from India.
DOI: http://dx.doi.org/10.3126/ajms.v6i3.10288
Asian Journal of Medical Sciences Vol.6(3) 2015 87-90
Pyogenic granuloma of tongue: A rare case report
Authors: Sonam Sharma  , Amita Sharma  , Ashok Kumar  , Shivani Kalhan  , Jasmine Kaur  
Published: January 2025

Pyogenic granuloma (PG) is a kind of inflammatory hyperplasia in response to chronic irritation. Here, we report a case of 64 year old male patient with PG on midline of the dorsum of the posterior third of the tongue. Its differential diagnosis, the importance of biopsy findings in establishing definitive diagnosis and about the new approaches for its treatment is discussed.
DOI: http://dx.doi.org/10.3126/ajms.v6i3.10619
Asian Journal of Medical Sciences Vol.6(3) 2015 84-86
Fungus infected atrial myxoma: A rare cause of infective endocarditis and chordae rupture
Authors: Gökhan Özmen  , Kübra Doganay  , Hasan Ari  , Tolga Dasli  , Ahmet Tutuncu  , Mehmet Melek  , Mehmet Demir  , Erhan Tenekecioglu  
Published: January 2025

Case reports are increasing about infected myxomas. Infection with bacteria is relatively much more but fungus infected atrial myxomas are exteremely rare and may complicate the disease course. As our knowledge this is the first fungus infected myxoma report in Turkish population.
DOI: http://dx.doi.org/10.3126/ajms.v6i3.11045
Asian Journal of Medical Sciences Vol.6(3) 2015 81-83
Role of fibreoptic bronchoscopy and CT guided FNAC in diagnostic evaluation of Non resolving Pneumonia with special emphasis on clinical outcome
Authors: Bhupendra Kumar Jain  , Pooja Sharma  , Ashok Bajpai  , Satish Motiwale  , Nikhilesh Pasari  , Deepika Patel  
Published: January 2025

Background: Nonresolving pneumonia is a pneumonia with a delayed or slow resolution of radiographic infiltrates or clinical symptoms despite adequate treatment with antibiotics for a minimum period of 10 days. Fibreoptic bronchoscopy (FOB) and CT guided FNAC has a specific role in diagnosis of Non resolving pneumonia.
Aims and Objectives: To assess the diagnostic efficacy of fibreoptic bronchoscopy (FOB) and computed tomography (CT)- guided fi ne needle aspiration cytology (FNAC) in evaluation of non-resolving or slowly resolving pneumonia with special emphasis on clinical outcome.
Material and Methods: The study was designed as a prospective observational study. We reviewed FOB in Sixty-five consecutive patients of Non-resolving pneumonia admitted under Respiratory Medicine unit of Sri aurobindo medical college and PG Institute Indore from June 2012 to May 2014. We also reviewed role of CT guided FNAC in selected case where FOB result was inconclusive.
Result: Out of total Sixty-five case of non resolving pneumonia, Fifty-two patient (81%) were diagnosed with the help of FOB and Eleven patients (91%) were diagnosed with help of CT guided FNAC out of Twelve patient subjected for procedure.
Conclusion: FOB should be the first option before CT-guided FNAC in evaluating non-resolving pneumonia. Both the procedures were safe and no major complication was observed.
DOI: http://dx.doi.org/10.3126/ajms.v6i3.10727
Asian Journal of Medical Sciences Vol.6(3) 2015 66-71
Insights of HBV Pathogenesis and Emerging Clinical Therapies for HBV Induced HCC Patients for a Better Prognostic Outcome
Authors: Reshmi Chatterjee  , Abhisek Mitra  
Published: January 2025

Chronic hepatitis B (CHB) virus infection is a global epidemic and a major cause of hepatocellular carcinoma (HCC). Approximately, 400 million people with 1.5 million Americans are chronically infected with this virus and around 1 million deaths from HBV annually have been estimated. High serum viral load has been detected between 75-80% of HCC patients. Epidemiological studies revealed that there are geographical variations in the incidence rate of hepatitis B virus genotype and subgenotypes. Furthermore, HBV induced HCC has a direct correlation with the recurrent genomic integration of this virus and cross-talk of its oncogenic protein HBV x (HBx) with different cellular signaling pathways. With the help of an extensive pathological study, whole genome sequencing and molecular insights of HBV induced HCC patients, suitable medications providing high-genetic barrier to resistances are made available. These medications can prevent HCC by inhibiting viral replication, modulating the immune response or both. The evolution of drugs with superior efficacy and less toxicity are providing important tools for clinicians to reduce HBV related HCC. This review sheds new perspective on molecular insight of HBV life cycle and clinical updates to treat sustained virus infection and associated cancers.
DOI: http://dx.doi.org/10.3126/ajms.v6i4.11884
Asian Journal of Medical Sciences Vol.6(4) 2015 1-8
Strengthening adverse drug reaction reporting in Nepal
Authors: Nisha Jha  , Devendra Singh Rathore  , Pathiyil Ravi Shankar  , Sudesh Gyawali  , Mohamed Azmi Hassali  , Mohammed Alshakka  , Thamir M. Alshammri  
Published: January 2025

Pharmacovigilance in Nepal is still in infancy. Till date only healthcare professionals are involved and the problem of underreporting is seen. The national pharmacovigilance centre is located in the national regulatory authority of Nepal, i.e. Department of Drug Administration (DDA). Lack of adequate human resources for managing the pharmacovigilance program in Nepal has been a limitation for the growth of pharmacovigilance activities. Currently, there is neither any involvement of community pharmacists in Adverse Drug Reaction (ADR) reporting process nor any involvement of consumers for the same. This paper reviews the current status of pharmacovigilance and mentions possible benefits of involving consumers or patients in the existing pharmacovigilance program. A systematic review were conducted by searching different databases like PubMed, Google scholar, EMBASE, NepJOL, and Scopus. This study also describes the role of healthcare professionals in ADR reporting, possible reasons for underreporting of ADRs, regulatory perspectives and benefits of involving consumers in pharmacovigilance.
DOI: http://dx.doi.org/10.3126/ajms.v6i4.11659
Asian Journal of Medical Sciences Vol.6(4) 2015 9-13
Ghost cell odontogenic cyst : A rare case with literature review
Authors: B.N. Shivakumar  , Santhosh Reddy  , Barakha Nayak  , Nehal Rathore  
Published: January 2025

Gorlin in 1962 described calcifying odontogenic cyst (COC) for the first time as a separate entity. It is an odontogenic cyst with notable presence of histopathological features which contains a cystic lining demonstrating “Ghost” cells with a propensity to calcify. COC shows diversity of variants according to its clinical, histopathological & radiological characteristics. A case of calcifying odontogenic cyst is reported with its review of literature.
DOI: http://dx.doi.org/10.3126/ajms.v6i4.11586
Asian Journal of Medical Sciences Vol.6(4) 2015 83-86
A case of single ventricular heart, pulmonary atresia, patent ductus arteriosus, major aortopulmonary collateral arteries
Authors: Rema V Nair  , Velayudhan Nair  , RV Mookambika  , RG Mohandas Rao  , SN Somayaji  
Published: January 2025

We report a case of multiple congenital anomalies in a female newborn infant, born to themother from a hill tribe. The Doppler echocardiography of the baby showed large atrial septaldefect amounting to single atrium, atretic left atrioventricular valve, large single right sidedventricle, aorta shifted to the left arising from single ventricle and diminutive hypoplasticleft ventricle. Right atrioventricular valve was normal forming single inlet into the ventricle.Pulmonary artery was small and hypoplastic and no antegrade fl ow was observed in it. Thepatient was diagnosed as having single ventricle, pulmonary atresia, patent ductus arteriosus(PDA) and major aortopulmonary collateral artery (MAPCA).
DOI: http://dx.doi.org/10.3126/ajms.v6i4.7660
Asian Journal of Medical Sciences Vol.6(4) 2015 96-98
Sarcomatoid Carcinoma: A Rare and unusual histological variant of prostatic carcinoma
Authors: Amit Gupta  , Bhavesh Chaddha  , Puneet Prakash  , Priya Pathak  , Neelam Wadhwa  
Published: January 2025

Carcinosarcoma of Prostate also known as Sarcomatoid carcinoma is a rare biphasic malignancy with a malignant epithelial component (carcinomatous) and a malignant mesenchymal component. We report a case of this rare and unusual histological variant of prostatic carcinoma.
DOI: http://dx.doi.org/10.3126/ajms.v6i5.12336
Asian Journal of Medical Sciences Vol.6(5) 2015 69-70
Placental malarial parasitaemia and pregnancy outcome among parturients in a tertiary hospital in South- South Nigeria
Authors: Godwin J Ibanga  , Aniekan M Abasiattai  , Emem A Bassey  , Michael Ukpe  , Olujimi A Olatunbosun  , Udeme Ekrikpo  
Published: January 2025

Background: Malaria is the most common human parasitic disease and continues to be a complex and overwhelming global health problem, especially in sub-Saharan Africa. Placental malaria, one of the major features of malaria in pregnancy has been associated with serious adverse health consequences to both the mother and her fetus.
Objective: This study sought to determine the prevalence of maternal, cord, and placental malarial parasitaemia at parturition, the association between maternal and placental parasitaemia, and also the association between placental parasitaemia and pregnancy outcomes.
Materials and Methods: A descriptive cross-sectional design was used to study 330 pregnant women selected by the systematic random sampling technique as they presented in the labour ward of University of Uyo Teaching Hospital, Uyo between April, 2012 and September, 2012. Pre-delivery, maternal peripheral blood was taken for malaria parasite (MP) and packed cell volume (PCV). Post delivery, cord blood was taken for MP and PCV estimation while placental blood was examined for MP. Neonatal demographic and clinical characteristics were also obtained. The data was analyzed using SPSS version 17. Level of statistical significance was set at P less than 0.05 (P < 0.05).
Results: The mean age of the respondents was 28.8 ± 4.4 years. The prevalence of maternal, cord, and placental parasitaemia were 30.3%, 14.8% and 18.2% respectively. There was a strong correlation between maternal parasitaemia and placental parasitaemia (rho = 0.75, P< 0.001). Also, a significant linear association between cord parasitaemia and placental malaria (rho = 0.87, p< 0.001) was found. Placental malaria predisposed to low birth weight (OR 1.01{95%CI 1.001 – 1.02}, p = 0.04) and fetal anaemia (OR 1.02{95%CI 1.01 – 1.03}, p < 0.001.
Conclusion: There is a relatively high prevalence of placental parasitaemia at parturition. Placental malaria is associated with adverse pregnancy outcomes such as low birth weight, fetal anaemia and cord parasitaemia. Proven strategies to prevent malaria in pregnancy such as use of ITNs and IPT and free antenatal care should be intensified to curb this deadly but preventable disease.
DOI: http://dx.doi.org/10.3126/ajms.v6i6.12401
Asian Journal of Medical Sciences Vol.6(6) 2015 53-59
Idiopathic hypokalemic periodic paralysis: A series of cases clustered in a part of Eastern India
Authors: Joydeep Mukherjee  , Durga Prasad Chakraborty  , Uma Sinharoy  , Shankar Prasad Saha  
Published: January 2025

Background: Most of the studies on hypokalemic periodic paralysis (HOPP) in India and abroad had described secondary causes as the origin of the disease. We had observed a series of HOPP cases clustered within 40 kilometers around Bankura, a district town of West Bengal, Eastern India. The aim of our study was to probe into the clinical, biochemical and electrophysiological details of the cases, which were found to be idiopathic.
Material and Methods: 32 idiopathic HOPP cases, attending the neurology OPD or admitted in Bankura Sammilani Medical College & Hospital (BSMCH), were selected from October 2006 to May 2008. All the secondary causes of HOPP were excluded. The patients were evaluated and the data was analyzed.
Results: Cases were clustered within a 40-kilometer radius from Bankura town, location of BSMCH. Male: female = 4.3:1. Median age of onset was 23.5 years (4-50 years). Median number of attacks was 2.5, (1 to 70); duration 3 hours - 6 days, median 3 days. Strenous physical activity was most common precipitating factor. 25% had bulbar symptoms, 9.4% had bladder dysfunction and 46.9% had diminished to absent deep tendon reflexes. Mean serum potassium = 2.45 mEq/L (1.4 – 3.1 mEq/L).
Conclusion: We had observed a group of idiopathic HOPP cases within a relatively small area in a short span of time in contrast to most other Indian studies, where the share of idiopathic aetiology is comparatively smaller. This underscores the importance of a larger study with genetic analysis on the aetiology of the idiopathic HOPP in this area.
DOI: http://dx.doi.org/10.3126/ajms.v6i6.12482
Asian Journal of Medical Sciences Vol.6(6) 2015 83-87
Case report on Ewing's sarcoma with review of literature
Authors: Agrawal Sonam , Vanita C Rathod  , Pankaj Kumar Agrawal  , Swati Saluja  
Published: January 2025

Ewings sarcoma is a highly malignant primary mesenchymal neoplasm of bone,which was first reported in 1921 by Ewing. The exact cell of origin of Ewing Sarcoma is not known it is generally believed that the lesion arises from either the endothelial cells of the blood vessels within the bone or from the undifferentiated reticulo-endothelial cell. Primitive neuroectodermal tumors (PNETs) arises from mesenchymal stem cells that differentiates along neural cell lineage. Reports of Ewings sarcoma constitute about 10% of all malignant bone tumor. A case of Ewings sarcoma in 10 year old male patient is reported, who visited to Dept of Oral and Maxillo-facial Pathology in Rungta College of Dental Sciences And Research, with chief complaint of pain and swelling in right side of face since 1 month. Early diagnosis of this case helps in selecting the appropriate treatment procedure and to avoid further complication.
DOI: http://dx.doi.org/10.3126/ajms.v6i6.12283
Asian Journal of Medical Sciences Vol.6(6) 2015 88-92
Sex determination using mastoid process
Authors: Jigyasa Passey  , Suniti R Mishra  , Rahul Singh  , K Sushobhna  , Shailendra Singh  , Priyanka Sinha  
Published: January 2025

Objective: Osteometric studies using individual bones have been a topic of interest among researchers. Such researches are a tool for conducting studies related to evolution, demographic profiles and forensic sciences. Skull is important in this regard as it resists adverse environmental conditions over time. The mastoid process can thus be used as a marker of sex as well as ancestry of individuals and populations. The aim of this study was to evaluate the use of mastoid process as a tool for sex determination in unidentified skeleton.
Materials and Methods: 70 (44 male and 26 female) complete undamaged skulls of known sex were used for the study. Mastoid length was recorded on the right and left mastoid process in each skull. Measurements were made with a digital vernier caliper.
Results: Statistics revealed high significance (p<0.0001) for the mastoid length for sex determination.
Conclusion: Reports on the use of mastoid process as a tool for sex estimation in unidentified human skeleton have been reported in different populations. The present study supports this finding among the Indian population.
DOI: http://dx.doi.org/10.3126/ajms.v6i6.12406
Asian Journal of Medical Sciences Vol.6(6) 2015 93-95
Are the adverse psychiatric outcomes reflection of occupational stress among nurses: An exploratory study
Authors: Anuradha Davey  , Parul Sharma  , Sanjeev Davey  , Arvind Shukla  , Kajal Srivastava  , Shaili Vyas  
Published: January 2025

Background: Stress-related disorders encompass a broad array of conditions, including psychological disorders such as depression and anxiety etc. Among healthcare professionals, nurses have been found to be most prone to burnout.
Aims and Objective: 1) To find out the prevalence of recent stress among staff nurses in terms of somatic symptoms, anxiety, social dysfunction and depression and; 2) To find out the association between these psychiatric outcomes and various socio-demographic variables, inter-personal relationships, working environment and professional stress.
Materials and Methods: Institutional based cross sectional study conducted on 100 staff nurses. Goldberg and Hillier’s 28-item scaled version of the General Health Questionnaire (GHQ-28) was used to measure the psychological aspect of quality of life of Staff nurses.
Results: The most common psychological outcome noted was the social dysfunction (94%) among the staff nurses. For anxiety, potential stressor were doctors’ attitude, insufficient salary and separate wash room for females; whereas significant association was found between depression and unsatisfactory attitude of doctors, fellow nurses, not enough time for rest and not getting enough holidays.
Conclusion: Social dysfunction could be cause or effect of other psychiatric manifestations like anxiety or depression
Asian Journal of Medical Sciences Vol.7(1) 2015 96-100
Fenetheylline in the Middle East, a thriving trade in the post-Saddam era
Authors: Ahmed M Lutfi  
Published: January 2025

Aims and Objectives: To collect up-to-date knowledge using a systematic review of the literature and to get evidence-based data concerning Fenethylline, and its illegal commerce in the region of the Middle East after 2003.
Materials and Methods: Four main medicalliterature databases were scrutinized using a list of pre-specified keywords. Additionally, social networks, and other resources were utilized to retrieve relevant data. The total number of references that were used in this paper is twenty-two.
Results: The literature search was conducted from the 3rd of December to the 29th of December 2015. The search was done from Baghdad, Iraq via the Earth link-Telenet Internet Service Provider (ISP). The Total Search Engine Results Pages (SERPs) were 463137. The highest SERPs were for the keywords “Amphetamine” and “Fitton.” Google Scholar and PubMed were the databases that scored the highest SERPs. Captagon is a dangerous psychoactive substance. Its production was officially stopped in the 1980s. Currently, Captagon, and counterfeit Captagonare being illegally produced in South-East Europe and trafficked to the region of the Middle East.
Conclusion: In the post-Saddam era of the Middle East, this substance has been traded and distributed at an exponential rate. The main explanation is that the rise of this illegal commerce is related to the chaos and the lack of order in the regions of conflict and civil war in Syria and Iraq in particular.
Asian Journal of Medical Sciences Vol.7(4) 2016 116-119
Intradiploic meningioma- A rare osteolytic calvarial lesion: A case report and review of literature
Authors: Sandeep B V  , Kaushik Roy  , Manpreet Singh Banga  , Partha Ghosh  
Published: January 2025

Meningiomas are most commonest benign intracranial neoplasm which are encountered in clinical practice. One of the most uncommon variant is intradiploic meningiomas, which can present as osteoblastic or osteolytic calvarial lesion and should be considered as differential diagnosis. We here present a rare case report of osteolytic intradiploic meningioma of skull presenting as scalp mass with a background of head injury and discuss its management.
Asian Journal of Medical Sciences Vol.7(5) 2016 103-105
Myasthenia gravis: A rare presentation
Authors: Sandeep Lahiry  , Dipak Bhowmik  
Published: January 2025

Myasthenia gravis (MG) is a relatively rare autoimmune disorder in which antibodies form against acetylcholine (Ach) nicotinic postsynaptic receptors at the neuromuscular junction of skeletal muscles. The usual initial complaint is a muscle weakness but can also present as respiratory failure, as in our case. MG is treated with medications such as Acetylcholine-esterase (AChE) inhibitors or immunosuppresants and, in selected cases, thymectomy.
Here, we present a case of 32 year old women with MG, who presented with an unexplained respiratory failure. She was stabilized with mechanical ventilation and subsequently treated with immunoglobins and thymectomy.
Asian Journal of Medical Sciences Vol.7(5) 2016 100-102
A-V malformation of nose: A rare challenging case
Authors: Gaurab Ranjan Chaudhuri  , Ruma Guha  , Rajesh Hansda  , Soumendra Nath Bandyopadhyay  
Published: January 2025

Congenital A-V malformations of head-neck region are extremely uncommon lesions encountered in clinical practice. They may lead to a wide array of clinical effects from cosmetic disfigurement and recurrent life threatening haemorrhage to cardiac failure. Treatment of these lesions pose a challenge to reconstructive surgeons due to their extreme vascularity, high incidence of recurrence and involvement of adjacent vascular channels. The case presented here is a congenital A-V malformation treated successfully by thorough surgical excision and reconstruction by a well vascularised flap.
Asian Journal of Medical Sciences Vol.8(1) 2017 94-97