bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pre-University Health Professional Students' Readiness and Perception Toward Interprofessional Education
Authors: Sahoo Rashmirekha , Sahoo Soumendra , Kyaw Soe Htoo Htoo , Rai Sharada , Singh Jaspal 
Published: January 2022

Background:
Interprofessional education (IPE) helps preparing the learners in all healthcare professions to work effectively in collaborative teams. This study was undertaken to assess the readiness and perception of IPE of preuniversity health professional students even before they enter their health professional courses.

Methods:
The preuniversity health professional students along with final-year medical and dental students were recruited for the study. The readiness for interprofessional learning scale was used to measure the student's readiness toward IPE before the interprofessional-related activity session. The preuniversity students also completed the IEPS scale after their interaction with final-year medical and dental students.

Results:
Most of the aspiring health professional students during their foundation year expressed positive attitude toward readiness for IPE. Most preuniversity students realized that by learning with various professional students would make them effective member of healthcare team. The students had positive perception toward competence and autonomy, perceived need for cooperation, perception of actual cooperation, and understanding other's value, which were significantly higher from score 3 of somewhat disagree (P < 0.001).

Conclusion:
Most of the aspiring health professional students in their preuniversity year expressed positive attitude toward readiness for IPE although were not prepared to take roles and responsibility within the interprofessional group. They could well perceive the need for cooperation, perception of actual cooperation, and understanding other's value while working in an IP team.
Immunoglobulin-G Antibodies against Severe Acute Respiratory Syndrome – Coronavirus-2 among Health-Care Workers
Authors: Prakash Om , Solanki Bhavin , Sheth Jay , Acharya Hemendra , Acharya Swati , Vinzuda Mital , Patani Hari 
Published: January 2022

Background:
Seropositivity among health-care workers (HCWs) may help in better understanding of the immune response after COVID-19 infection.

Objectives:
To estimate seropositivity among HCWs and to compare available variables with seropositivity to understand the factors affecting seropositivity.

Materials and Methods:
A serosurveillance among HCWs was carried out using population proportion sampling during the second half of October 2020 in the city of Ahmedabad using the Covid-Kavach (immunoglobulin G [IgG] ELISA Antibody testing kit). Simple proportions and appropriate statistical tests were used as needed.

Results:
As on October' 2020, HCWs in Ahmedabad demonstrated a seropositivity of 20.84% (95% confidence interval [CI] 19.00–22.81%). Seropositivity among HCWs was lower than that of the general population (24.20%) which was estimated as part of the same study. Female HCWs had higher seropositivity 22.14% (95% CI 19.74–24.74%) as compared to 18.82% (95% CI 16.06–21.93%) among male HCWs and the difference was statistically not significant (Z = 1.66, P = 0.097). Age groups with increasing age show increasing trend in the seropositivity among HCWs.

Conclusion:
As on October 2020, with 20.84% seropositivity among HCWs in Ahmedabad, one in every five HCW already demonstrate IgG antibodies against severe acute respiratory syndrome– coronavirus-2. Further scientific studies on seropositivity and the factors affecting the seropositivity may be carried out to uncover more details of immune reaction after COVID-19 infection.
Diagnostic Accuracy of Calculated Tumor Volumes and Apparent Diffusion Coefficient Values in Predicting Endometrial Cancer Grade
Authors: Kakkar Chandan , Gupta Kamini , Jain Kunal , Narang Vikram , Singh Aminder , Saggar Kavita , Bansal Namita , Cioni Dania , Neri Emanuele 
Published: January 2022

Background:
Magnetic resonance imaging (MRI) has been shown to be an accurate imaging technique for the preoperative assessment of local staging of endometrial cancer and for evaluating the depth of myometrial invasion.

Materials and Methods:
This was a single-center retrospective study performed on patients with histopathologically proven endometrial carcinoma who underwent an MRI examination of the pelvis between October 2017 and May 2020.

Results:
In the present analysis, mean apparent diffusion coefficient (ADC) values for each histologic grade were 0.72 ± 0.13 × 10−3 mm2/s (G1), 0.76 ± 0.17 × 10−3 mm2/s (G2), and 0.74 ± 0.12 × 10−3 mm2/s (G3), respectively, showing no significant correlation between ADC values and tumor grade (P = 0.73). Overall, ADC minimum was significant in differentiating grades of endometrial carcinoma (P = 0.02) with the ability to differentiate Grade I and II lesions (P = 0.01). A mean tumor volume of 25.2 cc could differentiate low-grade tumors (Grade I and Grade II) from high-grade tumors (Grade III) with a sensitivity and specificity of 88% and specificity of 89%. The tumor volume/uterine volume ratio (TV/UV) differentiates high-grade tumors from low-grade tumors (P < 0.001), however, no significant difference in the ratio was observed among Grade I and II lesions (P = 0.48). The area under the curve of tumor volume was 0.875 (95% confidence interval 0.0–1.00) (P = 0.001), indicating that tumor volume was an effective tool for distinguishing high-grade and low-grade endometrioid adenocarcinomas. The corresponding sensitivity and specificity were 88.0% and 89.0%, respectively.

Conclusion:
Preoperative noninvasive radiological assessment for tumor volume, TV/ UV or tumor volume/uterine volume is important surrogate markers for preoperative prognostication of endometrial carcinoma.
Prescription-Event Monitoring Study on Safety and Efficacy of Levonadifloxacin (Oral and I.V.) in Management of Bacterial Infections
Authors: Mehta Yatin , Sutar Anand R. , Zirpe Kapil , Kothari Jay Narendra , Alapati Chakravarthi , Pathak Manu , Nagvekar Vasant C. , Mehta Kapil Dev , Debnath Khokan 
Published: January 2022

Background:
Levonadifloxacin is a novel broad-spectrum antibiotic belonging to the benzoquinolizine subclass of quinolones. It is available in intravenous as well as oral formulation for the treatment of infections caused by common Gram-positive bacterial pathogens including methicillin-resistant Staphylococcus aureus (MRSA).

Patients and Methods:
This study retrospectively assessed the real-world safety and efficacy of levonadifloxacin (oral and/or IV) in the treatment of 1229 patients across various clinical conditions. Study outcomes were clinical and microbiological success at the end of therapy.

Results:
The mean duration of levonadifloxacin therapy was 7.2 days, with a time to clinical improvement averaging at 4 days. Three hundred and three patients received oral therapy, 875 received IV, and 51 received a combination of IV followed by oral therapy. Patients were prescribed levonadifloxacin for skin and soft-tissue infections, diabetic foot infections, septicemia, catheter-related bloodstream infections, bone and joint infections, febrile neutropenia, and respiratory infections including COVID-19 pneumonia. High clinical success rates of 98.3%, 93.7%, and 96.1% with oral, IV, and IV followed by oral levonadifloxacin, respectively, were obtained. Only 11 mild adverse events were reported in 9 patients which included constipation, diarrhea, hyperglycemia, nausea, fatigue, and vomiting. Overall, 96.3% and 97.3% of investigators rated the efficacy and safety of levonadifloxacin as “good to excellent.”

Conclusions:
An excellent safety and efficacy profile of levonadifloxacin was observed in this study making it a suitable treatment option for management of various bacterial infections, including those caused by resistant Gram-positive pathogens such as MRSA and quinolone-resistant S. aureus.
A study of quality of sleep, quality of life, and cognition in elderly
Authors: Jadhav Samiksha , Subramanyam Alka Anand , Raut Nitin B. , Singh Shipra 
Published: January 2022

Background:
Sleep plays a vital role in maintaining optimum physical and mental functioning and can be implicated in affecting the quality of life (QOL) and cognition in elderly population. This study aims to assess quality of sleep, QOL and to assess the effect of quality of sleep on QOL and cognition in elderly population

Materials and Methods:
A cross-sectional study was done in elderly population in which 30 were healthy control, 30 depressed, and 30 with mild neurocognitive disorder (NCD) who were assessed using Pittsburg Sleep Quality Index, World Health Organization QOL (WHOQOL)-BREF, Geriatric Depression Scale-Short form, and Addenbrooke's Cognitive Examination Scale-Revised (ACE-R). Statistical analysis was done using SPSS 20 software using descriptive methods and Pearson's correlation test.

Results:
Mean Pittsburgh Sleep Quality Index (PSQI) score was the lowest and mean WHOQOL-BREF score highest in healthy control compared to elderly with mild NCD and depression, the difference being statistically significant in both cases (P < 0.01). PSQI scores have negative correlation with the ACE-R scores when studied in healthy control group (P < 0.05, r = −0.136) and WHOQOL-BREF domain scores overall (P < 0.01 r = −0.485, −0.497, −0.350, −0.475).

Conclusion:
Quality of sleep in elderly with depression and mild NCD is lower as compared to healthy control. Sleep may affect QOL and cognition in elderly and thus it would be essential to screen and identify sleep-related issues and intervene early.
Cognitive status of older adults with diabetes mellitus, hypertension, and dyslipidemia on Hindi Cognitive Screening Test and Saint Louis University Mental State
Authors: Tripathi Rakesh Kumar , Tripathi Shailendra Mohan , Pandey Nisha Mani , Srivastava Anamika , Usman Kauser , Ali Wahid , Tiwari Sarvada C. 
Published: January 2022

Background:
Hindi cognitive screening test (HCST) and Saint Louis University Mental Status (SLUMS) Examination both claim that they are bias-free cognitive screening tests. HCST is highly sensitive and specific in screening Indian older adults. However, SLUMS is more comprehensive in terms of assessing visuospatial and memory functions. The present study presents and compare cognitive status of older adults with diabetes mellitus (DM), hypertension (HT), and dyslipidemia (DL) on HCST and SLUMS.

Methods:
The sample comprised of 150 older adults ≥60 years included in a consecutive series. Participants and their family members, giving written informed consent, residing permanently in central catchment areas Chowk, Lucknow, constituted the study sample. Semistructured sociodemographic details and medical history proforma, Socioeconomic Status (SES) Scale, General Health Questionaire – 12, SLUMS and HCST were administered. Blood pressure was measured by Medical Research Assistant. Biochemical investigations for DM and DL were carried out. Participants were categorized into two groups: (1) case groups (112): DM only + HT only + DL only and (2) control group (38): Without discernable abnormality of physical illness on the basis of invesigations. Data were analyzed using percentage, mean, standard devitation SD, Chi-square, and t-test.

Results:
There was a statistically significant difference on cognitive status between control and DM group on recall, reading, copying (P < 0.05 level), and on writing (P < 0.01) on HCST. A statistically significant difference was also found in writing (P < 0.01) between control and HT group. A statistically significant difference was found between control and DL on recall (P < 0.05) and writing (P < 0.01). According to SLUMS control and DM group differ significantly (0.01) for delayed recall and with HT and DL group on visuospatial function.

Conclusion:
Cognitive status of older adults with DM, HT, and DL was found to be significantly impaired on specific domains as compared to the control group.
Life skill training workshop in geriatric mental health for postgraduate students
Authors: Pandey Nisha Mani , Tripathi Rakesh Kumar , Tiwari Samyak 
Published: January 2022

Background:
Management of mentally ill elderly is a challenging task. Due to the lack of awareness, training opportunities in the course curriculum, and nil to negligible knowledge/ understanding/ exposures, allied mental health professionals are hardly available in geriatric mental health (GMH). Awareness generating orientation/ skill development workshops/ seminars/ webinars/ conferences may develop the interest in the young generations, which further may help in generating human resources in the subject. The present article aims to provide a snapshot of the Life Skill Training (LST) workshop developed for psychology students and discusses its effectiveness.

Materials and Methods:
The authors had an opportunity to organize and facilitate orientation workshop named as “life skill training in GMH“ for the students of psychology in Varanasi. A total of 86 students had participated in two independent workshops. All participants' self-rated appraisal was obtained on a five-point scale (ranging from very poor to very good) for all ten core life skills as laid out by the World Health Organization. The workshop was conducted by applying the tools such as imagination, reflection, communication, presentation, problem-solving, critical thinking, and sharing. The pre-post assessment was done, and qualitative feedback was received from the participants.

Results:
The results reveal that participants observed betterment in self on each life skill as the obtained value of mean scores after the workshop was found to be slightly more on each of the core life skills.

Conclusion:
The orientation workshop sensitizes the students regarding the issues related to the field, which may allow them to pursue the subject further.
Cytomorphological Categorization of Thyroid Lesions according to The Bethesda System for Reporting Thyroid Cytology and Correlation with their Histological Outcome
Authors: Kamboj Meenakshi , Mehta Anurag , Pasricha Sunil , Gupta Gurudutt , Sharma Anila , Durga Garima 
Published: January 2022

Objective:
The objective of this study was to report the experience of an Indian premiere tertiary care oncology center in reporting fine needle aspiration cytology of thyroid lesions according to the Bethesda system of reporting thyroid cytopathology (TBSRTC) given by National Cancer Institute (NCI). These were then correlated with their histopathological outcome, analyzing the level of specificity and sensitivity of the procedure.

Material and Methods:
Aspiration cytology of thyroid lesions, presented during a 5.5-year duration, was reported retrospectively and prospectively, according TBSRTC, and correlated with their histopathologic diagnosis.

Results:
A total of 431 patients were evaluated comprising 289 females and 142 males, with a median age of 52 years. Among the cytological categories 80 (18.6%) were non-diagnostic (ND), 131 (30.2%) benign, 45 (10.4%) follicular lesion of undetermined significance (FLUS), 27 (6.3%) follicular neoplasm, 33 (7.9%) suspicious for malignancy (SM), and 115 (26.7%) malignant. Histopathology reports were available in 142 of these cases. Final malignant diagnosis was reported in 11 of 14 ND (78.6%), 5 of 18 benign cases (27.7%); 9 of 17 FLUS (52.9%), 7 of 13 FLUS (53.89%), 19 of 20 SM (95%), and 58 of 60 malignant cases (96.7%). The procedure had sensitivity of 94.4%, specificity of 61.9%, positive predictive value of 90.3% and negative predictive value of 72.22%.

Conclusion:
TBSRTC provides uniform categorization of thyroid cytology, which also helps in further management. This valid system has helped to streamline the reporting terminologies as well as the clinical management.
Circulating serum amyloid A levels but not SAA1 variants predict long-term outcomes of angiographically confirmed coronary artery disease
Authors: Yeh Kuan-Hung , Hsu Lung-An , Juang Jyh-Ming Jimmy , Chiang Fu-Tien , Teng Ming-Sheng , Tzeng I-Shiang , Wu Semon , Lin Jeng-Feng , Ko Yu-Lin 
Published: January 2022

Objectives:
Circulating serum amyloid A (SAA) levels are strongly associated with atherosclerotic cardiovascular disease risk and severity. The association between SAA1 genetic variants, SAA levels, inflammatory marker levels, and coronary artery disease (CAD) prognosis has not been fully understood.

Materials and Methods:
In total, 2199 Taiwan Biobank (TWB) participants were enrolled for a genome-wide association study (GWAS), and the long-term outcomes in 481 patients with CAD were analyzed. The primary endpoint was all-cause mortality, and the secondary endpoint was the combination of all-cause death, myocardial infarction, stroke, and hospitalization for heart failure.

Results:
Through GWAS, SAA1 rs11024600 and rs7112278 were independently associated with SAA levels (P = 3.84 × 10−145 and P = 1.05 × 10−29, respectively). SAA levels were positively associated with leukocyte counts and multiple inflammatory marker levels in CAD patients and with body mass index, hemoglobin, high-density lipoprotein cholesterol, and alanine aminotransferase levels in TWB participants. By stepwise linear regression analysis, SAA1 gene variants contributed to 27.53% and 8.07% of the variation of the SAA levels in TWB and CAD populations, respectively, revealing a stronger influence of these two variants in TWB participants compared to CAD patients. Kaplan–Meier survival analysis revealed that SAA levels, but not SAA1 gene variants, were associated with long-term outcomes in patients with CAD. Cox regression analysis also indicated that high circulating SAA levels were an independent predictor of both the primary and secondary endpoints.

Conclusion:

SAA1 genotypes contributed significantly to SAA levels in the general population and in patients with CAD. Circulating SAA levels but not SAA1 genetic variants could predict long-term outcomes in patients with angiographically confirmed CAD.
Structural and optical characteristics of poly(vinyl alcohol)/carboxymethyl cellulose/ curcumin nanocomposites
Authors: Ahmed E. , Aboelkhair A. , M. Abdelghany A. 
Published: January 2022

ABSTRACT. Curcumin nanoparticles (CurNP’s) were successfully synthesized, characterized, and used as a cross-linking dopant of polyvinyl alcohol/ sodium carboxymethyl cellulose (PVA/CMC) semi-natural polymer blend. Synthesized nanocomposite films of (PVA/CMC/CurNP’s) were characterized using Fourier transforms infrared FTIR spectroscopy and tested for their resistance of different bacterial grams. Obtained data shows that studied PVA polymerized and cross-linked with CMC as a result for hydrogen bonding between the carboxylic groups and with the non-substituted hydroxyl groups of the cellulose molecule. The optical energy gap was found to be sensitive for the CurNP’s doping level, and the indirect transition was dominant in the studied samples. The addition of CurNP’s appears to increase the activity index of all samples against both gram-negative and positive bacteria, and their activity increases with increasing dopant level until a specific optimal concentration.

KEY WORDS: Curcumin nanoparticles, Semi-natural polymer blend, Antibacterial, FTIR, Optical energy gap

Bull. Chem. Soc. Ethiop. 2021, 35(3), 615-624.
DOI: https://dx.doi.org/10.4314/bcse.v35i3.12
Novel 6-aryl-7-alkyl/aryl-[1,2,4]triazolo[4,3-a][1,3,5]triazine-5(6H)-thiones, processes for their preparation, characterization and evaluation of their in vitro antioxidant activity
Authors: Hajri A. , Alimi D. , Rtibi K. , Sebai H. 
Published: January 2022

ABSTRACT. A series of nine new 6-aryl-7-alkyl/aryl-[1,2,4]triazolo[4,3-a][1,3,5]triazine-5(6H)-thiones (2a-i) were synthesized by a reaction of N-triazol-3-yl imidates (1) with three different isothiocyanate derivatives (RNCS) in refluxing toluene. The structures of the final heterocyclic compounds were confirmed by 1H-NMR, 13C-NMR, FT-IR, elemental analysis, and mass spectral analysis. The target compounds (2a-i) were in vitro screened for their activity as antioxidants using DPPH (2,2′-diphenyl-1-picrylhydrazyl) and FRAP (ferric reducing/antioxidant power) methods. The results revealed that some triazolotriazine-5-(6H)thiones exhibited antioxidant activity ranging from moderate to high. The obtained findings revealed that the triazolotriazine-5-(6H)thiones (2g, 2h, and 2i) have superiority among all compounds, It is obvious that the presence of a hydroxyl group in the structure is essential for the antioxidant properties and should be taken into consideration in further design of structures with potential antioxidant properties.

KEY WORDS: Imidates, Isothiocyanates, Antioxidant, Triazole, DPPH, FRAP

Bull. Chem. Soc. Ethiop. 2021, 35(3), 565-572.
DOI: https://dx.doi.org/10.4314/bcse.v35i3.8
En torno a la Academia del Arcadia: ilustres admitidas e ilustres excluidas
Authors: Aguilar González Juan 
Published: January 2022

La Academia de la Arcadia supuso, desde su creación, un excelente auspicio para las mujeres que deseaban ejercer la escritura. Las escritoras de la Arcadia formaron un nutrido grupo que, si bien dentro del canon impuesto, destacó por la calidad de algunas de sus componentes hasta el punto de llegar a formar parte de las antologías masculinas de la época y siglos posteriores.
No obstante, no todo fue positivo, pues quedaron fuera de la institución poetas de talento cuyo estilo de vida no congeniaba con el estilo que sus fundadores quisieron imprimir a la Arcadia. Al menos, Cristina Dudley y Teresa Zani, entre otras, vieron su labor poética reconocida en diversas antologías.
Clima organizacional, su impacto en el desempeño académico y la eficiencia laboral de los alumnos pertenecientes a la licenciatura de contador público
Authors: González Saúl 
Published: January 2022

El objetivo de esta investigación es analizar y presentar un panorama del clima organizacional, su impacto en el desempeño académico y en la eficiencia laboral de los alumnos de la licenciatura de contador público. El análisis de la investigación se apoya mediante la aplicación de una escala de Likert, en donde los datos obtenidos se procesarán en un software especializado SPSS versión 5.0 y se resumirán en su totalidad para analizarse y presentar una propuesta a la Jefatura de División de la Licenciatura de Contador Público perteneciente al Tecnológico de Estudios Superiores de Jocotitlán, para que sirva de base a la oportuna toma de decisiones.
Abstract
The objective of this research is to analyze and present an overview of the organizational climate, its impact on the academic performance and work efficiency of students in the Bachelor's Degree in Public Accountancy. The analysis of the research is supported by the application of a Likert scale, where the data obtained will be processed in a specialized software SPSS version 5.0 and will be summarized in its totality to be analyzed and to present a proposal to the Division Head of the Bachelor's Degree of Public Accountant belonging to the Tecnológico de Estudios Superiores de Jocotitlán, to serve as a basis for timely decision making.
empresas familiares
Authors: Patiño Martínez Arely Viridiana 
Published: January 2022

Se ha documentado que en las EF contratan mujeres que no necesariamente son las dueñas o fundadoras pero que de cierta manera ejercen liderazgo en las mismas, ocupan puestos estratégicos que les permiten tomar decisiones de pronta respuesta y que determinan en ciertas ocasiones el beneplácito o desaprobación de la propia empresa. Sin embargo, aún no se ha explorado el perfil de las mujeres en ese ámbito, siendo éste la principal aportación a la literatura que se pretende obtener mediante la elaboración de este proyecto.
Abstract
It has been documented that women are hired in the FE who are not necessarily the owners or founders, but who in a certain way exercise leadership in the same, occupy strategic positions that allow them to make quick response decisions and sometimes determine the approval or disapproval of the company itself. However, the profile of women in this field has not yet been explored, and this is the main contribution to the literature that we intend to obtain through the development of this project.