bluuebunny/crossref_metadata_2025_split huggingface dataset:
Scenario Analysis of Water-Saving Potential in Yeast Manufacturing Industry under the Guidance of Water Intake Quota
Authors: Zhang Yubo , Bai Xue 
Published: April 2022

While yeast manufacturing consumes a large amount of water per unit of product, water use efficiency varies widely within the industry due to disparity in water-saving technologies. By stipulating water intake per unit of product, the Norm of Water Intake––Part 41: Yeast Production (GB/T 18916.41-2019) will standardize production water use and improve the water-saving level of the yeast manufacturing industry. This paper estimates the industry’s production capacity from 2020 to 2024 through regression analysis. It examines the distribution of water use efficiency under different policy scenarios based on the standard for water intake, including the business-as-usual scenario, the bottom-line scenario, the ideal scenario, and the expected scenario. Then, the water use of the yeast manufacturing industry under different scenarios is calculated, and the water-saving potential is analyzed by comparing it with the business-as-usual scenario. The results indicate that depending on the intensity of policy implementation, the average annual water savings will range from

2.5
×
106

m

3

to

14
×
106

m

3

. The cumulative water savings will add up to

16
×
106

m

3

to

51
×
106

m

3

in the next five years, which is very large.
Severe Short Bowel Syndrome: Prognosis for Nutritional Independence Through Management by a Multidisciplinary Nutrition Service and Surgery
Authors: Yeh Daniel D. , Vasileiou Georgia , Mulder Michelle , Byerly Saskya , Ripat Caroline , Byers Patricia M. 
Published: April 2022

Introduction Short bowel syndrome (SBS) is a debilitating condition associated with significant morbidity and mortality. Historically, SBS patients require indefinite parenteral nutrition (PN) and endure lifelong nutritional challenges. The purpose of this study was to review the outcomes, specifically nutritional independence, of a multidisciplinary nutrition service. Methods A retrospective analysis of SBS patients followed by our surgical nutrition service was performed. Patients without 1-year follow-up were excluded. Demographics and nutritional parameters were collected at 4 intervals: initial presentation, 1-year, 2-year, and 5-year follow-up. Short bowel syndrome anatomical subtypes identified through operative reports were characterized as end jejunostomy, jejunocolonic, or jejuno-ileocolonic with ileo-cecal valve intact. Intestinal failure was defined by the requirement of PN, while intestinal insufficiency was defined by enteral support requirement. Clinical outcomes examined included mortality, fistula closure, and nutritional independence. Results The study cohort comprised 89 patients, 50 of whom had ≤ 100 cm intestinal length. Mean age was 57 ± 17y, 55 (62%) were female, and median initial intestinal length was 77 [60-120] cm. Short bowel syndrome was complicated by fistulas in 47 (53%) of patients. Overall mortality was 13%, and 67 (75%) were liberated from PN. A total of 58 (65%) underwent operative intervention and fistula closure was achieved in 37 of 47 (79%) patients. Conclusions Short bowel syndrome patients can experience significant benefit under treatment by a multidisciplinary nutrition service. By incorporating surgical intervention, the majority of patients previously relegated to lifelong PN have the opportunity to become nutritionally independent within 5 years.
Spanish Version of the Death Attitude Profile-Revised. Translation and Validation Into Spanish
Authors: Cruzado Juan Antonio , Ibáñez del Prado Celia , Carrascosa Pujalte Elisa , Wong Paul T. P. , Eisenbeck Nikolett , Carreno David F. 
Published: April 2022

The Death Attitude Profile-Revised (DAP-R) was developed in English-speaking cultures with the aim of measuring attitudes towards death. This measure consists of 32 items, grouped into five factors (Fear of Death, Avoidance of Death, Neutral Acceptance, Approach Acceptance, and Escape Acceptance). The DAP-R was translated and adapted to Spanish (DAP-RSp), and the psychometric properties were analyzed accross a general sample. The face validity was evaluated by 20 experts in palliative care. N = 417 (X = 39.06 years) took part in the validation. DAP-RSp showed adequate internal consistency (Cronbach’s alpha ranging from 0.67 for Neutral Acceptance to 0.95 for Escape a Acceptance, and 0.88 for the total), a multitrait scaling analysis and a confirmatory factor analysis reproduced the five dimensions of the original scale. The Spanish version of the DAP-R can be used as a valid scale to assess attitudes towards death in Spanish speaking population.
Association between varicose vein and atrial fibrillation—a population-based study in Taiwan
Authors: Hu Wei-Syun , Lin Cheng-Li 
Published: April 2022

Objective This study retrospectively explores the association between varicose vein and atrial fibrillation (AF). Methods The data are from Taiwan National Health Insurance Research Database. The univariate and multivariable-adjusted hazard ratios (HR), with corresponding 95% confidence intervals (CI), for the occurrence of AF between the varicose vein cohort and comparison cohort were estimated using cox proportional hazards models after adjustment for age, sex, and comorbidities. Results The incidence rates of AF in the varicose vein and the comparison cohort were 4.82 per 1000 person-years and 3.47 per 1000-person years, respectively. After controlling for all the confounding variables, subjects with varicose vein were associated with a significantly higher risk of AF (adjusted HR = 1.23, 95% CI = 1.04–1.45) compared with the comparison cohort. Conclusions Our study is the first to show that varicose vein correlates to AF.
Promises and Pitfalls of Dyads in the National Diabetes Prevention Program: Lifestyle Coach Perspectives
Authors: Baucom Katherine J.W. , Bauman Tali , Nemirovsky Yanina , Gutierrez Chavez Manuel , Aguirre Monique C. , Ramos Carmen , Asnaani Anu , Gutner Cassidy A. , Ritchie Natalie D. , Shah Megha , Clark Lauren 
Published: April 2022

Purpose To describe Lifestyle Coach perceptions of dyads (i.e., family members and/or friends) in the National Diabetes Prevention Program (NDPP). Design Qualitative evaluation of cross-sectional survey responses. Setting Online. Participants Lifestyle Coaches (n=253) with experience teaching at least one in-person year-long NDPP cohort at a CDC-recognized organization. Measures Survey included items on background and experience with dyadic approach, as well as open-ended items on the benefits and challenges observed when working with dyads in the NDPP. Analysis Lifestyle Coach background and experience were analyzed descriptively in SPSS. Open-ended responses were content coded in ATLAS.ti using qualitative description, and then grouped into categories. Results Most Lifestyle Coaches (n=210; 83.0%) reported experience delivering the NDPP to dyads. Benefits of a dyadic approach included having a partner in lifestyle change, superior outcomes and increased engagement, and positive “ripple effects.” Challenges included difficult relationship dynamics, differences between dyad members, negative “ripple effects,” and logistics. Conclusion Lifestyle Coaches described a number of benefits, as well as some challenges, with a dyadic approach to the NDPP. Given the concordance between close others in lifestyle and other risk factors for type 2 diabetes, utilizing a dyadic approach in the NDPP has the potential to increase engagement, improve outcomes, and extend the reach of the program.
The Impact of Education and Insurance Status on Past-Year Dental Visits Among Older Mexican Adults: Results From the 2001 and 2012 Mexican Health and Aging Study
Authors: Archuleta Jennifer , Beltrán-Sánchez Hiram 
Published: April 2022

Objective: This study assessed past-year dental visits among older Mexican adults from the Mexican Health and Aging Study (MHAS). MHAS is a nationally representative cohort study of adults 50 years and older from Mexico. Methods: Baseline data from 2001 were compared with 2012 data. Binary logistic regression identified significant predictors of past-year dental visits. Decomposition techniques examined factors that contributed to changes in dental visits between 2001 and 2012. Results: Education and insurance status were positively associated with past-year dental visits, while decomposition results showed that population composition (more adults receiving insurance and higher education over time) contributed to the increased prevalence of dental visits between 2001 and 2012. Discussion: Education and insurance are critical factors that govern access to oral healthcare. After the provision of universal dental coverage by Mexico’s Seguro Popular in 2003, our results may reflect promising effects of such programs, which can inform future policies in Mexico and other settings.
Forming analysis and process study for a 6082 aluminum alloy automobile control arm in the process of forging
Authors: Wang Daoyong , Chai Mu , Tian Ying 
Published: April 2022

To reduce the weight of vehicles and save on fuel consumption, the forming analysis and process study for a 6082 aluminum alloy automobile control arm were conducted, and the results are reported here. First, the parameters of the constitutive equation of the 6082 aluminum alloy are determined, and the forming process and the dies of the stretch rolling, bending, and die-forging are proposed and discussed according to the given contours of the control arm. Then, the control arm is simulated by means of Deform-3D, the experiment results of the automobile control arm are compared with the simulation results, and the tensile strength, yield strength, and elongation of the test bars obtained from the control arm can meet the mechanical performance requirements based on the tensile test rig. Finally, the relationship of the die load, die wear, workpiece damage, and workpiece equivalent stress with different processing parameters are analyzed, and the effects of different solid solution times on the strength of control arm are discussed. The results show that when the friction coefficient is 0.3, the die temperature is 250°C, the forging velocity is 230 mm/s, the strain rate is 1s−1 and the solid solution time is 30 min, the die load, die wear, workpiece damage, workpiece equivalent stress, and the mechanical strength are then in a good state. The results of this research provide a reliable basis and analysis method for the forging of aluminum alloy automobile control arms.
Multidisciplinary Health Care Professionals’ Perceptions About Pediatric End of Life Discussions: A Cross-Sectional Survey and Needs Analysis
Authors: Georgadarellis Alexandria G. , Chu Tzu-Chun , Mason Katherine E. 
Published: April 2022

Background Pediatric end of life (EOL) care involves complex coordination of providers from multiple disciplines. Many of these providers’ experiences have not been completely described. Aim This study aims to explicate the alignment and divergence of health care professionals’ perceptions of the training, timelines, comfort, and effectiveness of pediatric EOL discussions as well as identify methods to improve medical education training. Design A cross-sectional survey was conducted. Analyses included Fisher’s exact and post-hoc tests for all pairwise comparisons. Setting/participants A total of 160 of 508 eligible participants at a single academic Department of Pediatrics completed the survey (response rate 31%). Participants included attending physicians, fellows, residents, mid-level providers, nurses, and social workers. Results Sixty percent thought EOL discussions occurred late and 70% thought discussions should occur earlier. Attending physicians were more likely to think discussions occurred late and should occur earlier ( P <.01). Residents and fellows were more likely to think participating in and leading discussions was stressful ( P <.02 and P <.01, respectively). Respondents that were female, younger than forty years old, had been in their provider role less than five years, or were residents and fellows were more likely to agree that these discussions led to changes in plan of patient care ( P <.05). Conclusions The majority of multidisciplinary pediatric health care professionals believe pediatric EOL discussions are stressful, occur too late, and should occur earlier. Future efforts in medical education should prioritize curriculum development focusing on workshops and simulations.
Outcomes of upper arm axillary artery and brachial artery arteriovenous grafts
Authors: Fermawi Sarah Ali , Fadia Rueshil , Chong Chyi Chyi , Berman Scott , Rybin Denis , Siracuse Jeffrey J , Zhou Wei , Tan Tze-Woei 
Published: April 2022

Background: We compared the outcomes of upper arm arteriovenous grafts (AVGs) in a large, prospectively collected data set to determine if there are clinically significant differences in axillary artery-based and brachial artery-based AVGs. Methods: Patients who received upper arm AVGs within the Society of Vascular Surgery Vascular Quality Initiative (VQI) dataset were identified. The primary outcome measures were primary and secondary patency loss at 12-month follow-up. Other outcomes included were wound infection, steal syndrome, and arm swelling at 6-month follow-up. The log-rank test was used to evaluate patency loss using Kaplan–Meier analysis, and Cox proportional hazards models were used to examine adjusted association between inflow artery (brachial artery vs axillary artery) and outcomes, adjusting for configuration (straight vs looped). Results: Among 3637 upper extremity AVGs in the VQI (2010-2017), there were 510 upper arm brachial artery AVGs and 394 upper arm axillary artery AVGs. Patients with axillary artery AVGs were more likely to be female (72% vs 56%, p < 0.001) and underwent general anesthesia (61% vs 57%, p < 0.05). In univariable analysis, the 12-month primary patency (54% vs 63%, p = 0.03) and secondary patency (81% vs 89%, p = 0.007) were lower for axillary artery AVGs than upper arm brachial artery AVGs. In multivariable analysis, although wound infection and arm swelling were similar at 6-month follow up, axillary artery AVGs were more likely to have steal syndrome (adjusted Hazard Ratio (aHR) = 2.6, 95% Confidence Interval (CI) 1.2,5.6, p = 0.017). In addition, axillary artery AVGs were associated with higher rates of 12-month primary patency loss (aHR = 1.6, 95% CI 1.2–2.2, p = 0.002) and 12-month secondary patency loss (aHR = 2.0, 95% CI 1.3–3.3, p = 0.005). Conclusions: From this observational study analyzing the outcomes of upper extremity hemodialysis access, axillary artery AVGs were associated with significantly lower patency rates and higher risk of steal syndrome than brachial artery AVGs.
COVID 19 and the Opioid Epidemic: An Analysis of Clinical Outcomes During COVID 19
Authors: Ezie Chiemeka , Badolato Ryan , Rockas Mary , Nafiz Rayek , Sands Brian , Wolkin Adam , Farahmand Pantea 
Published: April 2022

Background and Objectives: Here we aimed to characterize clinical outcomes in those receiving treatment at a Veterans Health Administration (VHA) methadone maintenance treatment program (MMT) during the COVID 19 pandemic in which SAMSHA regulations for MMTs were changed to provide a greater number of methadone allotments and decreased clinic-visit frequency. Methods: We report results of a single-site, pre-post cohort study of urine drug screen data 3 months before and after an increase in allotments of take-home medication from the methadone clinic. One hundred twenty-nine patients met inclusion criteria for this study. The study was reviewed by the NYHHS IRB committee and granted final approval by the Research and Development Committee. Results: The sample was predominately male, average age 66years and average years in most recent treatment is 4.1 years. No statistical significance was found between period 1 and period 2 in the positive test detection for nonprescribed opiates, methadone and illicit substances ( P > .05), number of new medical illnesses or overdoses. We controlled for participant age, substance use disorder diagnosis, psychiatric disorder diagnosis, and number of years in treatment. Discussion/Conclusions: The results of the study illustrate the relative safety of the changes made at this particular MMT during the pandemic. Additionally, there was continued adherence to methadone treatment with minimal change in illicit substance use during period 1 and period 2. Scientific Significance: To these authors’ knowledge this paper is one of the first to examine clinical outcomes in those with opioid addiction prescribed methadone from MMTs during the COVID 19 pandemic.
Changes in blood lipids in patients with chronic hepatitis B after 48 weeks of tenofovir alafenamide treatment: A prospective real-world clinical study
Authors: Zhang Yeqiong , Li Zhipeng , Luo Qiumin , Xu Wenxiong , Wang Lu , Zhu Shu , Peng Liang , Xie Chan 
Published: April 2022

Background Tenofovir alafenamide (TAF) is a new anti-hepatitis B virus nucleotide analogue that can cause dyslipidaemia in AIDS patients, but the effect of TAF on blood lipids in patients with chronic hepatitis B (CHB) is unknown. This study aimed to evaluate the effect of TAF on blood lipid levels in patients with CHB. Methods One hundred and twenty-one CHB patients were recruited as TAF group, including 69 treatment-naïve patients and 52 patients with nucleoside/nucleotide analogue experience before TAF treatment. All patients were followed up regularly for 48 weeks. Total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and triglyceride (TG) levels and the incidence of dyslipidaemia before and after TAF treatment were compared. Results After 48 weeks of TAF treatment, the levels of TC, TGs and LDL-C in TAF group were significantly higher than those in control group. In TAF group, the TC and TG levels were significantly higher than that at baseline. Baseline TC and TGs levels had a significant effect on the incidence of abnormal TC and TG levels after 48 weeks treatment. The LDL-C decreased slightly but not significantly. The proportion of patients with TC abnormalities increased from 20.7% at baseline to 26.3% at week 48, LDL-C abnormalities decreased from 50.4% to 42.5% and TG abnormalities increased from 14.2% to 22.5%. There were no significant differences compared with control group, as well as compared with baseline. Conclusions Tenofovir alafenamide treatment mainly affects the TC and TG level in patients with CHB but has little effect on LDL-C.
Effect of prior knowledge about treatment on cephalometric measurements
Authors: Prasad Sabarinath , Denotti Gloria , Farella Mauro 
Published: April 2022

Objective: We hypothesised that prior knowledge of details for a growth modification treatment influences cephalometric measurements and results in a detectable bias. Design: Observational study. Setting: University teaching facility. Methods: Six orthodontic residents assessed 48 lateral cephalograms taken before and after functional appliance treatment from 24 patients. The residents assessed six cephalometric measurements, (Cd-Pog, Cd-Me, Ar-Pog, Ar-Me, Go-Me, SNB) over three separate sessions, in either a random concealed order or as matched pairs with information about treatment and time disclosed. Results: When information was disclosed, five out of the six cephalometric measurements were significantly higher that the corresponding cephalometric measurements taken randomly with undisclosed information. The bias was in the range of 1.6–3.2 mm for linear measurements and was 1.1° for SNB. Conclusion: Disclosing treatment information does introduce systematic errors in cephalometric measurements. Cephalometric analysis in orthodontic clinical research should be carried out by assessors who are blinded to treatment details, to minimise risk of bias.
‘It feels like my visibility matters’: Women ageing with HIV overcoming the ‘violence of invisibility’ through community, advocacy and the radical act of care for others
Authors: Stevenson Jacqui 
Published: April 2022

Objectives: A participatory qualitative study exploring women’s experiences of ageing with HIV in London, United Kingdom. The research considered how the concept of ‘community’ was relevant to women’s experiences and what constructions of ‘community’ could be discerned in the experiences, accounts given and discourses employed by older women living with HIV. Methods: The research presented in this article was conducted as a PhD study between 2015 and 2019. The study was structured in multiple and overlapping phases, and adopted a feminist and participatory approach. The methods used in the research were as follows: participatory literature review, participatory creative workshops, policy review and stakeholder interviews, life story interviews, and a participatory analysis workshop. Results: Eighteen women living with HIV aged over 50 participated in creative workshops and fourteen women in life story interviews. Women’s experiences of ageing with HIV are shaped by intersecting identities, community responses, and personal connections. Ageing with HIV brings challenges, added to and augmented by other difficulties women face in their lives, but women draw on individual and community assets in order to adapt, cope and thrive. Belonging to a community of women living with HIV and a broader community of people living with HIV created a vital space of safety, in which women found support, advice, and meaning. Conclusions: Women ageing with HIV countered the ‘violence of invisibility’ through forming community with other women living with HIV, rejecting stigma, and enacting a personal form of advocacy through care for others.
The Clinician’s Guide to Baseball Pitching Biomechanics
Authors: Diffendaffer Alek Z. , Bagwell Michael S. , Fleisig Glenn S. , Yanagita Yuki , Stewart Megan , Cain E. Lyle , Dugas Jeffrey R. , Wilk Kevin E. 
Published: April 2022

Context: Improper baseball pitching biomechanics are associated with increased stresses on the throwing elbow and shoulder as well as an increased risk of injury. Evidence Acquisition: Previous studies quantifying pitching kinematics and kinetics were reviewed. Study Design: Clinical review. Level of Evidence: Level 5. Results: At the instant of lead foot contact, the elbow should be flexed approximately 90° with the shoulder at about 90° abduction, 20° horizontal abduction, and 45° external rotation. The stride length should be about 85% of the pitcher’s height with the lead foot in a slightly closed position. The pelvis should be rotated slightly open toward home plate with the upper torso in line with the pitching direction. Improper shoulder external rotation at foot contact is associated with increased elbow and shoulder torques and forces and may be corrected by changing the stride length and/or arm path. From foot contact to maximum shoulder external rotation to ball release, the pitcher should demonstrate a kinematic chain of lead knee extension, pelvis rotation, upper trunk rotation, elbow extension, and shoulder internal rotation. The lead knee should be flexed about 45° at foot contact and 30° at ball release. Corrective strategies for insufficient knee extension may involve technical issues (stride length, lead foot position, lead foot orientation) and/or strength and conditioning of the lower body. Improper pelvis and upper trunk rotation often indicate the need for core strength and flexibility. Maximum shoulder external rotation should be about 170°. Insufficient external rotation leads to low shoulder internal rotation velocity and low ball velocity. Deviation from 90° abduction decreases the ability to achieve maximum external rotation, increases elbow torque, and decreases the dynamic stability in the glenohumeral joint. Conclusion: Improved pitching biomechanics can increase performance and reduce risk of injury. SORT: Level C.