bluuebunny/crossref_metadata_2025_split huggingface dataset:
Coloniality and contagion: COVID‐19 and the disposability of women of color in feminized labor sectors
Authors: Flores Sanchez José M. , Kai Jade 
Published: October 2022

AbstractGrounded in the historical conditions of epidemics intertwined with state power, we examine the factors that contribute to women of color's high proximity to contagion. We build on significant contributions to scholarship on the racial and sexual politics of work and the colonial history of contagion to argue that colonialism is key in the state's weaponization of illness against entire populations. This is crucial to decipher how women of color in feminized labor sectors, in our case, cleaning services and nursing, confront death during the COVID‐19 pandemic. This transforms readers' understanding of governmentality within public health crizes and the roles of colonial state institutions in administering death in raced, gendered, and classed ways. We conclude that future studies focused on pandemics, labor, race, and gender must account for the ways in which colonialism positions feminized workers as fungible in structures of response to mass crizes.
Analysis of volatile compounds contributing to distinctive odour of silver carp (Hypophthalmichthys molitrix) surimi
Authors: Geng Haiyong , Chen Lihua , Wang Shufen , Wu Yi , Gao Pei , Jiang Qixing , Yang Fang , Xia Wenshui 
Published: October 2022

SummaryAlthough the characterisation of volatile compounds in silver carp (Hypophthalmichthys molitrix) have been studied, their respective contribution to specific odour feeling was unclear. Therefore, an investigation was made in this study by big data mining, solid phase microextraction‐gas chromatography–mass spectrometry (SPME‐GC–MS), odour activity values (OAVs), odour recombination in surimi models and omission experiment. The results demonstrated that 91 volatile compounds were obtained by data mining and 62 volatile compounds were identified by instrumental analysis. Among them, twenty‐one volatile compounds were initially selected for the construction of the surimi model. The odour recombination and omission experiment confirmed that characteristic odour of silver carp surimi were hexanal (fishy, grassy), octanal (grassy, fatty), (E)‐2‐octenal (fishy), nonanal (grassy, fatty), (E)‐2‐nonanal (fatty, grass), (E,E)‐2,4‐heptadienal (fishy), 1‐hexanol (grassy) and 1‐octen‐3‐ol (mushroom). This study specified distinct silver carp surimi odour with definite compounds.
Study on drying characteristics and moisture content prediction model of Panax notoginseng taproot by using segmented drying of microwave vacuum combined with hot air
Authors: Zhang Fujie , Shi Lei , Xin Lidong , Li Lixia , Tian Liquan , Cui Xiuming , Gao Yongping 
Published: October 2022

AbstractIn order to explore the drying characteristics of Panax notoginseng taproot (PNT) and realize the dynamic monitoring of moisture content in the segmented drying process of microwave vacuum combined with hot air, the PNT was conducted the experimental study under different convert moisture contents of wet basis (20, 30, 40 g•g−1), upper‐temperature limits (45, 50, 55°C), power densities (0.50, 0.75, 1.00, 1.50 W•g−1) and chamber pressures (1, 3, 5, 10 kPa). The dynamic changes in moisture ratio and drying rate under different drying conditions were studied, and a snake optimizer‐support vector regression (SO‐SVR) model was proposed to predict moisture content during the drying process. The results showed that the drying process mainly consisted of decreasing rate and constant rate, and the stage of constant rate occurred when the moisture content of the dry basis decreased from 1 to 0.5 g•g−1. In the stage of microwave vacuum, decreasing chamber pressure, increasing upper‐temperature limit and power density could increase the drying rate. In order to verify the prediction ability of SO‐SVR, this study carried out a comparative analysis between SO‐SVR and two famous prediction models (genetic algorithm‐support vector regression and particle swarm optimization‐support vector regression) through three evaluation indexes (coefficient of determination (R2), mean absolute error (MAE) and root mean square error (RMSE). The results showed that the prediction accuracy of the SO‐SVR model was the highest, and the R2, MAE, and RMSE of the prediction set were 0.9850, 0.0140, and 0.0173, respectively. Therefore, the SO‐SVR model is a feasible method to predict the moisture content of PNT during the segmented drying process of microwave vacuum combined with hot air.Practical ApplicationIn the condition of segmented drying of microwave vacuum combined with hot air, the drying technology and characteristics of PNT were explored and proposed a SO‐SVR model to dynamically monitor the moisture content. This method has important theoretical significance and practical value to improve the processing efficiency and quality in the process of Panax notoginseng production.
Parent‐adolescent conflict processes and their measurement: A systematic review
Authors: Marshall Sheila K. , Tilton‐Weaver Lauree , Shankar Sneha , Johnston Andrea 
Published: October 2022

AbstractConflicts are frequently incorporated into research on parent‐adolescent relationships. However, empirical research has inconsistently used “parent‐adolescent conflict” as a broad and often singular term rather than processes involving a range of constructs. To understand the balance of attention to the constructs involved in parent‐adolescent conflicts, we conducted a systematic review of measures that were reported in peer‐reviewed journal articles between January 1, 1970 and January 31, 2021, across several disciplines. The initial search identified 17,036 references; after removing duplicates, excluding studies based on stated criteria, and adding 22 articles from reference lists, 467 articles were retained, and 568 measures were extracted from articles. Two types of content analysis (directed and conventional) were used to organize measures into categories. Findings reveal that conflict frequency, intensity, and quality of interactions are most often used while initiation and duration tend to be overlooked. Uneven coverage may generate biases in understanding parent‐adolescent conflict processes.
Safe, supportive neighborhoods: Are they associated with childhood oral health?
Authors: Crouch Elizabeth , Nelson Joni , Radcliff Elizabeth , Merrell Melinda A. , Martin Amy 
Published: October 2022

AbstractObjectiveThere has been limited examination of how community‐level supports may influence oral health metrics among children. The purpose of our study is to examine the association between two types of community‐level positive childhood experiences and oral healthcare and oral health outcomes among children ages 6 to 17 years of age.MethodsThis study uses a cross‐sectional data set from the 2018–2019 National Survey of Children's Health. Two oral health metrics were used: preventive dental care, measured as one or more preventive dental visits in the past 12 months, and tooth decay, measured as tooth decay or cavities in the last 12 months. To quantify living in safe, stable, equitable environments, questions on residing in a safe and supportive neighborhood were used. Descriptive statistics and bivariate analyses were used to calculate frequencies, proportions, and unadjusted associations for each variable (n = 40,290). Multivariable logistic regression models were used.ResultsIn an adjusted analysis, children who lived in a supportive neighborhood had a higher likelihood of receiving a preventive dental visit than children who did not live in a supportive neighborhood (aOR 1.41; 95% CI 1.21–1.65). Children who lived in a safe neighborhood were less likely to have tooth decay than children who did not live in a safe neighborhood (aOR 0.75; 95% CI 0.65–0.86).ConclusionsThe findings from this study highlight the role of social structures in tightening the safety net for oral healthcare in children.
Mechanistic modeling reveals the importance of turgor‐driven apoplastic water transport in wheat stem parenchyma during carbohydrate mobilization
Authors: Verbeke Sarah , Padilla‐Díaz Carmen María , Martínez‐Arias Clara , Goossens Willem , Haesaert Geert , Steppe Kathy 
Published: October 2022

Summary
During stem elongation, wheat (Triticum aestivum) increases its stem carbohydrate content before anthesis as a reserve for grain filling. Hydraulic functioning during this mobilization process is not well understood, and contradictory results exist on the direct effect of drought on carbohydrate mobilization.
In a dedicated experiment, wheat plants were subjected to drought stress during carbohydrate mobilization. Measurements, important to better understand stem physiology, showed some unexpected patterns that could not be explained by our current knowledge on water transport. Traditional water flow and storage models failed to properly describe the drought response in wheat stems during carbohydrate mobilization. To explain the measured patterns, hypotheses were formulated and integrated in a dedicated model for wheat.
The new mechanistic model simulates two hypothetical water storage compartments: one where water is quickly exchanged with the xylem and one that contains the carbohydrate storage. Water exchange between these compartments is turgor‐driven. The model was able to simulate the measured increase in stored carbohydrate concentrations with a decrease in water content and stem diameter.
Calibration of the model showed the importance of turgor‐driven apoplastic water flow during carbohydrate mobilization. This resulted in an increase in stem hydraulic capacitance, which became more important under drought stress.
Demographic differences in understanding and utilization of ranked choice voting
Authors: Donovan Todd , Tolbert Caroline , Harper Samuel 
Published: October 2022

AbstractObjectivesNew York City is the largest U.S. jurisdiction to use ranked choice voting (RCV). We examine New York and other U.S. cities using RCV to assess if there were different levels of understanding and utilization of RCV across demographic groups.MethodsWe placed items on a survey conducted during the 2021 New York City RCV election that had been included in two previous surveys of different U.S. cities using RCV.ResultsWe find higher levels of reported understanding and rates of ranking multiple candidates in NYC than in other jurisdictions. We find no systematic differences by race/ethnicity in terms of reported understanding of RCV in NYC or the other samples. We also find no systematic association between age and reported understanding of RCV. Respondents with more education were more likely to report understanding RCV in each sample. People of color were less likely to report ranking multiple mayoral candidates in NYC and California, and respondents with more education were more likely to report ranking in two samples.ConclusionsApart from these important differences in utilization, our search for race/ethnic differences largely produced null results, suggesting RCV may not produce bias in who engages with it.
Geographic information system data considerations in the context of the enhanced bathtub model for coastal inundation
Authors: Williams Lauren Lyn , Lück‐Vogel Melanie 
Published: October 2022

AbstractThis study determines input data appropriateness for geographic information system‐based enhanced bathtub model (eBTM) modeling of coastal inundation in an urban setting. Various tests were conducted concerning digital surface models (DSMs) to determine: (a) the highest appropriate resolution achievable from available LiDAR data and consider variations between derived sub‐meter DSMs; (b) optimal DSM horizontal resolution for coastal inundation modeling based on “out‐the‐box” solutions; and (c) mechanisms to address the challenge presented by DSMs regarding overhanging structures for a study site in False Bay, South Africa. Results showed that while sub‐meter DSMs are achievable, low point cloud densities may result in the misrepresentation of structures, which affects the inundation extents. High horizontal resolution DSMs are required for inundation modeling in an urban setting to account for narrow thoroughfares. Challenges posed by first return LiDAR depicting bridges as solid structures could be circumvented by modifying the input water source for the eBTM processing.
An ex vivo platform to guide drug combination treatment in relapsed/refractory lymphoma
Authors: Goh Jasmine , De Mel Sanjay , Hoppe Michal M. , Mohd Abdul Rashid Masturah Bte , Zhang Xi Yun , Jaynes Patrick , Ka Yan Ng Esther , Rahmat Nur’Atiqa Diana Binti , Jayalakshmi  , Liu Clementine Xin , Poon Limei , Chan Esther , Lee Joanne , Chee Yen Lin , Koh Liang Piu , Tan Lip Kun , Soh Teck Guan , Yuen Yi Ching , Loi Hoi-Yin , Ng Siok-Bian , Goh Xueying , Eu Donovan , Loh Stanley , Ng Sheldon , Tan Daryl , Cheah Daryl Ming Zhe , Pang Wan Lu , Huang Dachuan , Ong Shin Yeu , Nagarajan Chandramouli , Chan Jason Yongsheng , Ha Jeslin Chian Hung , Khoo Lay Poh , Somasundaram Nagavalli , Tang Tiffany , Ong Choon Kiat , Chng Wee-Joo , Lim Soon Thye , Chow Edward K. , Jeyasekharan Anand D. 
Published: October 2022

Although combination therapy is the standard of care for relapsed/refractory non-Hodgkin’s lymphoma (RR-NHL), combination treatment chosen for an individual patient is empirical, and response rates remain poor in individuals with chemotherapy-resistant disease. Here, we evaluate an experimental-analytic method, quadratic phenotypic optimization platform (QPOP), for prediction of patient-specific drug combination efficacy from a limited quantity of biopsied tumor samples. In this prospective study, we enrolled 71 patients with RR-NHL (39 B cell NHL and 32 NK/T cell NHL) with a median of two prior lines of treatment, at two academic hospitals in Singapore from November 2017 to August 2021. Fresh biopsies underwent ex vivo testing using a panel of 12 drugs with known efficacy against NHL to identify effective single and combination treatments. Individualized QPOP reports were generated for 67 of 75 patient samples, with a median turnaround time of 6 days from sample collection to report generation. Doublet drug combinations containing copanlisib or romidepsin were most effective against B cell NHL and NK/T cell NHL samples, respectively. Off-label QPOP-guided therapy offered at physician discretion in the absence of standard options (
n
= 17) resulted in five complete responses. Among patients with more than two prior lines of therapy, the rates of progressive disease were lower with QPOP-guided treatments than with conventional chemotherapy. Overall, this study shows that the identification of patient-specific drug combinations through ex vivo analysis was achievable for RR-NHL in a clinically applicable time frame. These data provide the basis for a prospective clinical trial evaluating ex vivo–guided combination therapy in RR-NHL.
Association between socioeconomic status and mucosal healing in Japanese patients with ulcerative colitis: a cross-sectional study
Authors: Kitahata Shogo , Furukawa Shinya , Miyake Teruki , Shiraishi Kana , Tange Kazuhiro , Hashimoto Yu , Yagi Sen , Ninomiya Tomoyuki , Suzuki Seiyuu , Shibata Naozumi , Murakami Hidehiro , Ohashi Katsuhisa , Tomida Hideomi , Yamamoto Yasunori , Takeshita Eiji , Ikeda Yoshio , Hiasa Yoichi 
Published: October 2022

ObjectiveSocioeconomic status is a risk factor for worse outcomes in many diseases. However, evidence on the association between socioeconomic status and clinical outcome in patients with ulcerative colitis (UC) is limited. In the clinical setting, the therapeutic goal for UC is to achieve mucosal healing (MH). Thus, the aim of this study is to examine the association between socioeconomic status and MH in patients with UC.MethodsThe study population consisted of 298 patients with UC. Education status and household income were divided into three groups based on a self-administered questionnaire. MH and complete MH were defined as a Mayo endoscopic subscore of 0–1 and 0, respectively. The association of socioeconomic status with MH and complete MH was assessed by multivariate logistic regression analysis. Patients with UC were divided into a younger group (<51 years old) and an older group (≥51 years old) based on median age.ResultsThe percentage of MH and complete MH was 62.4% and 25.2%, respectively. In all patients, socioeconomic status was not associated with MH and complete MH, respectively. In the older group, education but not household income was independently positively associated with MH and complete MH. In contrast, in the younger group, no association between socioeconomic status and MH and complete MH was found.ConclusionIn older Japanese patients with UC, education status but not household income was independently positively associated with MH and complete MH.
Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic
Authors:   Global Health Research Group on Children’s Non-Communicable Diseases Collaborative
Published: October 2022

IntroductionChildhood cancer is a leading cause of death. It is unclear whether the COVID-19 pandemic has impacted childhood cancer mortality. In this study, we aimed to establish all-cause mortality rates for childhood cancers during the COVID-19 pandemic and determine the factors associated with mortality.MethodsProspective cohort study in 109 institutions in 41 countries. Inclusion criteria: children <18 years who were newly diagnosed with or undergoing active treatment for acute lymphoblastic leukaemia, non-Hodgkin's lymphoma, Hodgkin lymphoma, retinoblastoma, Wilms tumour, glioma, osteosarcoma, Ewing sarcoma, rhabdomyosarcoma, medulloblastoma and neuroblastoma. Of 2327 cases, 2118 patients were included in the study. The primary outcome measure was all-cause mortality at 30 days, 90 days and 12 months.ResultsAll-cause mortality was 3.4% (n=71/2084) at 30-day follow-up, 5.7% (n=113/1969) at 90-day follow-up and 13.0% (n=206/1581) at 12-month follow-up. The median time from diagnosis to multidisciplinary team (MDT) plan was longest in low-income countries (7 days, IQR 3–11). Multivariable analysis revealed several factors associated with 12-month mortality, including low-income (OR 6.99 (95% CI 2.49 to 19.68); p<0.001), lower middle income (OR 3.32 (95% CI 1.96 to 5.61); p<0.001) and upper middle income (OR 3.49 (95% CI 2.02 to 6.03); p<0.001) country status and chemotherapy (OR 0.55 (95% CI 0.36 to 0.86); p=0.008) and immunotherapy (OR 0.27 (95% CI 0.08 to 0.91); p=0.035) within 30 days from MDT plan. Multivariable analysis revealed laboratory-confirmed SARS-CoV-2 infection (OR 5.33 (95% CI 1.19 to 23.84); p=0.029) was associated with 30-day mortality.ConclusionsChildren with cancer are more likely to die within 30 days if infected with SARS-CoV-2. However, timely treatment reduced odds of death. This report provides crucial information to balance the benefits of providing anticancer therapy against the risks of SARS-CoV-2 infection in children with cancer.
Cortisol, cognition and Alzheimer’s disease biomarkers among memory clinic patients
Authors: Holleman Jasper , Adagunodo Sofia , Kåreholt Ingemar , Hagman Göran , Aspö Malin , Udeh-Momoh Chinedu T , Solomon Alina , Kivipelto Miia , Sindi Shireen 
Published: October 2022

ObjectiveThis study aims to investigate the relationship between diurnal cortisol patterns, cognition and Alzheimer’s disease (AD) biomarkers in memory clinic patients.MethodMemory clinic patients were recruited from Karolinska University Hospital in Sweden (n=155). Diurnal cortisol patterns were assessed using five measures: awakening levels, cortisol awakening response, bedtime levels, the ratio of awakening to bedtime levels (AM/PM ratio) and total daily output. Cognition was measured in five domains: memory, working memory, processing speed, perceptual reasoning and overall cognition. AD biomarkers Aβ42, total tau and phosphorylated tau were assessed from cerebrospinal fluid (CSF). Cognition was measured at follow-up (average 32 months) in a subsample of participants (n=57).ResultsIn assessing the associations between cortisol and cognition, higher awakening cortisol levels were associated with greater processing speed at baseline. No relationship was found between diurnal cortisol patterns and change in cognition over time or CSF AD biomarkers in the total sample. After stratification by CSF Aβ42levels, higher awakening cortisol levels were associated with worse memory performance in amyloid-positive participants. In amyloid-negative participants, higher bedtime cortisol levels and a lower AM/PM ratio were associated with lower overall cognition, greater awakening cortisol levels were associated with better processing speed, and a higher AM/PM ratio was associated with better perceptual reasoning. Additionally, higher awakening cortisol levels were associated with lower CSF Aβ42levels in amyloid-positive participants, while higher bedtime cortisol levels and a lower AM/PM ratio were associated with higher CSF total tau in amyloid-negative participants.ConclusionsOur findings suggest that diurnal cortisol patterns are associated with cognitive function and provide new insights into the association between diurnal cortisol patterns and AD-related CSF biomarkers. Further research is needed to examine the complex relationship between cortisol, cognition and brain pathology.
Addressing childcare as a barrier to healthcare access through community partnerships in a large public health system
Authors: Alvarez Kristin S , Bhavan Kavita , Mathew Sheryl , Johnson Courtney , McCarthy Amy , Garcia Blanca , Callies Marilyn , Stovall Kelly , Harms Michael , Kho Kimberly A 
Published: October 2022

ObjectiveIn our public health system, a survey of reproductive-aged women identified lack of childcare as the most common reason for missing or delaying healthcare. Community-based organisations (CBOs) in our county identified a similar need, so we partnered to develop a hospital-based childcare centre for patients to use during appointments.MethodsIn a large academic public health system, a partnership with a non-profit childcare CBO was formed to address lack of childcare as a barrier to accessing healthcare. Pilot clinics where no-cost childcare would be offered included obstetrics, gynaecology and medical oncology. Transparent communication from the CBO within the electronic medical record was built to minimally impact clinic workflows. Visual and electronic outreach, including patient portal questionnaires, were created to introduce patients to the services. Personalised clinic staff in-services were performed to introduce the service to clinics and leadership. Continual assessments of workflow were conducted and adjusted based on patient and staff feedback and quality checks. At 12 months, overall utilisation of the service was collected.ResultsIn the first 12 months that no-cost childcare was offered, 175 patients enrolled 271 children into the programme. Ninety-seven percent were women, primarily Hispanic (87/175 (50%)) or black (64/175 (37%)), with an average age of 31.8 years. Of the enrollees, 142/175 (81%) patients made 637 childcare appointments and 119/175 (68%) patients used at least one reservation for 191 children. Most patients were verbally referred by clinic staff for childcare or self-referred for childcare from clinic signage or paperwork. Childcare was requested most frequently for obstetrics and gynaecology appointments.