bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ameliorative Effects of Ethanolic Leaf extract of Diodia sarmentosa on high fat induced cardiac tissue injury in male wistar albino rats
Authors: Korie Stephen Chinedumije , Ezejiofor Tobias I.N 
Published: June 2022

Abstract
Background: Diodia sarmentosa is a native straggling herb found in Nigeria, especially in evergreen forest, bushland, and riverine areas. In folklore medicine, it has been used to treat ailments like diabetes, ulcers, etc. This study investigated the ameliorative effects of ethanolic leaf extract of Diodia sarmentosa on high-fat diet-induced cardiac tissue injury in male albino Wistar rats. Methods: Thirty (30) male Wistar rats (150g-200g) were divided into five (5) groups namely; Negative control (NC) group which was not induced nor treated, Positive control (PC) was induced but not treated, Low dose extract (LDE) was treated with 250mg/kg of the extract, High dose extract (HDE) was treated with 500mg/kg of the extract and SIM group treated with 5mg/kg of Simvastatin. Cardiac tissue injury was induced by feeding the rats with high-fat diet (Ghee and Coconut oil in the ratio of 3:1) for six (6) weeks. The administration of the treatments (extract and drug) at the appropriate doses started from the 4th week till the 6th week. Parameters like Total protein concentration, Lactate dehydrogenase (LDH) activity, Malondialdehyde level, Superoxide dismutase (SOD) activity, Catalase (CAT) activity, Glutathione S-transferase (GST) activity, and Glutathione peroxidase (GPx) activity were carried out in the cardiac tissue of the test rats to determine the ameliorative effects of Diodia sarmentosa. Results: Results obtained showed that high-fat diet reduced antioxidant enzymes, protein levels, and caused lipid peroxidation indicating injury in the cardiac tissue of the test rats. However, the extract at high dose significantly reduced (p<0.05) lipid peroxidation and high GST activity in the cardiac tissue caused by high-fat diet. Protein levels and antioxidant enzyme activities in SOD, CAT, GPx, and LDH were all significantly increased (p<0.05), when compared to the positive group. The extract at high dose possesses similar efficacy to the standard drug simvastatin used to compare the efficacy of the extract.Conclusions: Thee evidence from this study shows Diodia sarmentosa has the potential to improve and reverse the injury in the cardiac tissue caused by high-fat diet administration in the test rats, by reducing lipid peroxidation, and increasing antioxidant enzymes and total protein concentration. This makes the plant a potential new natural product for the treatment of cardiovascular diseases.
Dynamics of wage inequality during the pro-long economic transformation: The case of Vietnam
Authors: Doan Tinh 
Published: June 2022

Abstract
Using the RIF-decomposition to explore changes in wage inequality during the economic transformation in Vietnam, we find that real wages increased substantially during the period 1998-2010, but wage growth slowed down in the following period 2010-2020. Wage inequality increased in the former period, but declined considerably in the later one. Overall changes in wage inequality over the former period was mainly contributed by changes in labor market, job and workers’ observed characteristics, but in the later period the change was mainly contributed by the changes in returns to job and workers’ observed characteristics (wage structure effect). The economic structure change and increased supply of higher educated workforce have substantially contributed to the changing wage inequality over the past two decades. A rapid increase in supply of higher educated workers in the later stage of economic transformation has resulted in declining returns to education and thus has contributed to a decline in wage inequality.
Low Quality of life (QoL) in Indian breast cancer patients: a critical analysis of UP
Authors: Srivast Sanjiv , Srivast Alpana , Tiwari Sandeep 
Published: June 2022

Abstract
BackgroundBreast cancer is the most frequent cancer among women worldwide, and India is no exception to this devastating disease. Cancer can cause a variety of symptoms, some of which are complex and others which are not. Quality of Life is a word that encompasses physical, psychological, spiritual, and social components of quality of life. ObjectiveThe objective of this study is to evaluate quality of life in breast cancer patients who are getting treatment with various modalities at various stages of the disease.MethodsA total of 150 breast cancer patients were included in this cross-sectional investigation. Ferrel's Quality of Life Instrument-Breast Cancer Patient Version was used to assess patients' quality of life, and the instrument has already been validated by Ferrel BR et al (2012). General well-being, psychological well-being, distress, fearfulness, social concerns, and spiritual well-being are all included in these questions. ResultsThere was a link discovered between the type of cancer, the quantity of discomfort, and exhaustion (tiredness). However, no demographic factors (age, married status, or income) were shown to be significantly associated to QoL. Education and treatment type were found to be linked to QoL. ConclusionIn breast cancer patients, influencing quality of life (QoL) is a major concern. Apart from the effect of treatment, there are additional elements such as socioeconomic position, psychological well-being, fear of recurrence, and so on, which all play a role in a patient's well-being and can be improved if counselled at many levels such as family, hospital, and society.
Equilibration of a Synthetic Alzheimer 6-Protein Analog, 622-35, During RP-HPLC
Authors: Vyas Sandip B. , Duffy Lawrence K. 
Published: June 2022

Abstract:
The 1322-35 peptide (mol wt 1345 Da) of the Alzheimer 13-protein, AI3P, eluted as a series of oligomers during reversed-phase high-perfonriance liquid chromatography. Four distinct oligomers were resolved on the reversed­ phase surface, whereas size-exclusion chromatography indicated a single component with an approximate mol wt of 11kDa which suggested that the peptide existed as an octamer in solution.
Aspartate aminotranferase Thermus aquaticus YT-1. stability from the thermophilic bacterium Functional characterisation and stability
Authors: Raimo Gennaro , Cassar Mark , Masullo Mariorosario , Bocchini Vincenzo , Bannister William H. , Bannister Joe V. 
Published: June 2022

Abstract:
Aspartate aminotranferase from the thermophilic bacterium Thermus aquaticus has been purified to
homogeneity. The enzyme is pyridoxal-5-phosphate dependent and is composed of two subunits having an Mr
44000 each. T.aquaticus AspAT shows a pi of 4.5 and is a thermophilic enzyme exhibiting its maximum activity at 80°C in the pH range 7-8. Itis also resistant against denaturation to hea(and several chemical agents.
Studies on the Chemical Synthesis of Tick Anti-Coagulant Peptide (Tap)
Authors: Irving Stephen L , Mansfield Royston W 
Published: June 2022

Abstract:
Tick Anti-Coagulant Peptide (TAP) is a potent and selective inhibitor of blood coagulation Factor Xa. This 7 kDa polypeptide has been chemically synthesised using the Fmoc/t Bu solid phase method. Alternative cysteine
Protecting groups were explored for the synthesis and Cys(Trt) was found to be superior to Cys(Acm).
Impact of Motivation, Learning Strategy, and Intelligence Quotient on Medical Students' Grades
Authors: Febriza Ami , Sompa Andi Weri , Amaliah Asty , Padad Andi Tenri , Savitri Ary I. 
Published: June 2022

Background:
Medical students were faced with a problem-based learning (PBL) curriculum that required them to think critically. PBL requires a student to have the ability to think logically and collect integrated information, which is reflected in their IQ scores. Learning and motivation strategies were factors that could contribute to their academic achievement. High intelligence does not ensure academic achievement, and students need to recognize the learning strategies that work best for them. This study aimed to investigate the association of medical students' motivation for learning and their intelligence quotient with their course grades in their first semester.

Methods:
This study was an observational study of first-semester undergraduate medical students with 134 respondents. Intelligenz Struktur Test (IST) was used to assess IQ and the Motivated Strategies for Learning Questionnaire (MSLQ) form was used to measure students' academic motivation and their use of different learning strategies. Course grades were collected from their biomedical system course in the first semester. Linear regression analysis was used to determine the association between IQ scores and average biomedical grades.

Results and Discussion:
Linear regression analysis showed that IQ might play a role in determining biomedical system course grades both in the crude and adjusted analysis (p-value <0.001). None of the investigated motivation and learning scales modified the association between IQ scores and average biomedical grades.

Conclusion:
Intelligence can predict students' academic performance in their first semester courses. Motivation for learning did not differ between different IQ groups and did not modify the association between intelligence and academic achievement.
The Distribution of HIV and AIDS Cases in Luzhou, China, From 2011 to 2020: Bayesian Spatiotemporal Analysis
Authors: Ren Ningjun , Li Yuansheng , Wang Ruolan , Zhang Wenxin , Chen Run , Xiao Ticheng , Chen Hang , Li Ailing , Fan Song 
Published: June 2022

Background
The vastly increasing number of reported HIV and AIDS cases in Luzhou, China, in recent years, coupled with the city’s unique geographical location at the intersection of 4 provinces, makes it particularly important to conduct a spatiotemporal analysis of HIV and AIDS cases.

Objective
The aim of this study is to understand the spatiotemporal distribution of HIV and the factors influencing this distribution in Luzhou, China, from 2011 to 2020.

Methods
Data on the incidence of HIV and AIDS in Luzhou from 2011 to 2020 were obtained from the AIDS Information Management System of the Luzhou Center for Disease Control and Prevention. ArcGIS was used to visualize the spatiotemporal distribution of HIV and AIDS cases. The Bayesian spatiotemporal model was used to investigate factors affecting the spatiotemporal distribution of HIV and AIDS, including the gross domestic product (GDP) per capita, urbanization rate, number of hospital beds, population density, and road mileage.

Results
The reported incidence of HIV and AIDS rose from 8.50 cases per 100,000 population in 2011 to 49.25 cases per 100,000 population in 2020—an increase of 578.87%. In the first 5 years, hotspots were concentrated in Jiangyang district, Longmatan district, and Luxian county. After 2016, Luzhou’s high HIV incidence areas gradually shifted eastward, with Hejiang county having the highest average prevalence rate (41.68 cases per 100,000 population) from 2011 to 2020, being 2.28 times higher than that in Gulin county (18.30 cases per 100,000), where cold spots were concentrated. The risk for the incidence of HIV and AIDS was associated with the urbanization rate, population density, and GDP per capita. For every 1% increase in the urbanization rate, the relative risk (RR) increases by 1.3%, while an increase of 100 people per square kilometer would increase the RR by 8.7%; for every 1000 Yuan (US $148.12) increase in GDP per capita, the RR decreases by 1.5%.

Conclusions
In Luzhou, current HIV and AIDS prevention and control efforts must be focused on the location of each district or county government; we suggest the region balance urban development and HIV and AIDS prevention. Moreover, more attention should be paid to economically disadvantaged areas.
THE APPLICATION OF PICTURE WORD INDUCTIVE MODEL (PWIM) TO IMPROVE STUDENTS’ ACHIEVEMENTS IN WRITING DESCRIPTIVE TEXT
Authors: Sinurat Jernih D 
Published: June 2022

This study attempted to investigate the application of picture word inductive model (PWIM) to improve students’ achievements in writing descriptive text. The purpose of the study is to find out whether PWIM can improve students’ achievement in writing descriptive. This study was conducted by applying classroom action research. The subject of this study was the first year students ( X/A) of SMA Swasta Gajah Mada Medan. The data of this research were obtained in two cycles. The instrument used for collecting data was quantitative and qualitative. Based on the writing test result, the students’ score kept improving every test. The findings indicate that the using of PWIM as a media of learning improved students’ writing achievement. The students’ score significant improvement, the mean of second cycle i.e. 80.28 is higher that the mean of the first cycle i.e. 70.86. Based on diary notes, questionnaire sheet, observation sheet and interview, it was found that teaching learning process ran well. The conclusion is that the using of PWIM as a media of learning improves students’ writing Achievement.
THE IMPACT OF APPLYING ENGLISH SONG IN LISTENING COMPREHENSION
Authors: Murniaty Murniaty 
Published: June 2022

The study investigated about the sluggishness of students in English language lesson that caused them have low score. Due to that reason, it had researched teaching and learning process of listening comprehension. The students of one public junior high school, class VII were trained to listen songs as an experiment for several times in one semester, such as : folk songs, pop songs, etc. The research findings by applying Wilcoxon signed-rank test showed that Z &gt; 1,96, that is Z &gt; 5,147; which means there is significant difference after giving the treatment, or the score raised up about 5 – 10%. This indicates that students more understand the substance of the song also other English language materials, and more attractive and courage to learn English language.
AN ANALYSIS OF STUDENTS’ ABILITY IN WRITING NARRATIVE TEXT ( A STUDY AT THE EIGHTH GRADE OF SMP NEGERI 2 TAMBANGAN IN 2018/2019 ACADEMIC YEAR)
Authors: Hasibuan Asriani , Handayani Fitri 
Published: June 2022

This study aims to know the student’s ability in writing narrative text in terms of content, organization, vocabulary, language use, and mechanics mastery at the eightth grade of SMP Negeri 2 Tambangan and to know why the students’ ability in writing narrative text in terms of content, organization, vocabulary, language use, and mechanics mastery are low at the eighth grade of SMP Negeri 2 Tambangan. The research was conducted by using mix method(quantitative and qualitative research) with 9 students as the informants. The documentation and interview were used in collecting the data. Based on data analysis, it could be found (a)the result of the from their ability in writing narrative text in terms of content, organization, vocabulary, language use, and mechanics still below the criteria minimum (KKM). The average all of the participants just on average 65 while the KKM value demanded that they must except to get the score on the average of criteria minimum at 75. and b) The result of the data finding showed that most of the students are unable in writing narrative text includes in content, organization, vocabulary, language use, and mechanics. It is proved from their score n writing narrative text are still below the KKM. and c)Based on the writer’s interview to the 9 informants, most of students think writing is difficult skill for them because they have limited understanding in vocabulary, grammar and tenses mastery.
THEME IN INDONESIAN – ENGLISH TRANSLATION TEXT
Authors: Nasution Putri 
Published: June 2022

<p>This research is based on Linguistics Systemic Functional (LSF) and it observes the fronting idea and modeling in translation. Fronting idea can be seen from the Theme and the shift of Theme in a text ant its translation. This Theme and Rheme system is as part of LSF theory, whilst the ways or systems of translation are seen from Larson’s and Catford’s theories. There are sixteen different texts taken as data analyzed in this research from five different sources. They are from (1) The British Council Bulletin, (2) Political Speech; (3) Connexions Magazine; (4) Pelangi Magazine; (5) Islamic Speech Book. Each of the text is identified based on its Thematization including Marked and Unmarked Theme, Simple and Complex Theme, Singular and Plural Themes especially the Theme-Shift. From this analysis,, it can be also known the factors that cause the shifts of the Theme. The results of the analysis are: first, Plural Topical Marked Theme is the dominant Theme in both languages. Secondly, there are seven types of Theme shift in both languages, i.e. (1) the shift in simple Theme becomes complex or vice versa, (2) the shift in singular Theme becomes plural or vice versa, (3) the shift in marked Theme becomes unmarked ones or vice versa, (4) the shift in Theme position, (5) additional Theme, (6) omission, and (7) changing Theme. Thirdly, the factors that influence the Theme shifts in translation are caused by shifts of language units from Theme or Rheme or vice versa. Besides, it is also found that the additional of language units from English to Indonesian or vice versa, such as conjunctions, circumstance of place, manner, and time. On the contrary, it can also be caused by the existence of omission of language unit from English to Indonesian or vice versa. The shifts, additions, and omissions of language units cause and influence the forms, types, and the number of Themes from Singular Theme becomes plural ones and vice versa, and from Simple Theme becomes the complex ones or vice versa.</p>
Perlindungan Hukum Bagi Penerima Bilyet Giro Kosong Dalam Perspektif Perundang-Undangan
Authors: Mega Dwi Putri Mutiara , Suhermi Suhermi , Pahlefi Pahlefi 
Published: June 2022

This study aims to determine and analyze the form of legal protection for recipients of blank bilyet giro based on Decision Number 2470 K / Pdt / 2014 and Decision Number 423 / PDT / 2018 / PT DKI. Furthermore, to find out and analyze the publisher's responsibility regarding blank bilyet giro based on Decision Number 2470 K / Pdt / 2014 and Decision Number 423 / PDT / 2018 / PT DKI. The formulation of the problems in this study are 1) What is the form of legal protection for recipients of empty bilyet giro related to Decision Number 2470 K / Pdt / 2014 and Decision Number 423 / PDT / 2018 / PT DKI? 2) What is the publisher's responsibility regarding Decision Number 2470 K / Pdt / 2014 and Decision Number 423 / PDT / 2018 / PT DKI? This research method is normative legal research and uses a statutory approach, a case approach, and a conceptual approach. The result of this research is the legal protection provided to recipients of empty bilyet giro in the form of repressive legal protection in the form of regressive rights and claiming compensation and payment, by filing a lawsuit to the Court. The publisher's responsibility for issuing blank bilyet giro is to provide compensation and provide an object of guarantee to the recipient based on a court decision.
Abstrak
Penelitian ini bertujuan untuk mengetahui dan menganalisis bentuk perlindungan hukum bagi penerima bilyet giro kosong berdasarkan Putusan Nomor 2470 K/Pdt/2014 dan Putusan Nomor 423/PDT/2018/PT DKI. Selanjutnya untuk mengetahui dan menganalisis tanggung jawab penerbit terkait bilyet giro kosong berdasarkan Putusan Nomor 2470 K/Pdt/2014 dan Putusan Nomor 423/PDT/2018/PT DKI. Adapun rumusan masalah dalam penelitian ini adalah 1)Bagaimanakah bentuk perlindungan hukum bagi penerima bilyet giro kosong terkait dengan Putusan Nomor 2470 K/Pdt/2014 dan Putusan Nomor 423/PDT/2018/PT DKI? 2)Bagaimanakah tanggungjawat penerbit terkait Putusan Nomor 2470 K/Pdt/2014 dan Putusan Nomor 423/PDT/2018/PT DKI? Metode penelitian ini adalah penelitian hukum normatif dan menggunakan pendekatan peraturan perundang-udangan, pendekatan kasus, serta pendekatan konseptual. Hasil dari penelitian ini adalah perlindungan hukum yang diberikan bagi penerima bilyet giro kosong berupa perlindungan hukum represif berupa hak regres dan menuntut ganti rugi serta pembayaran, dengan mengajukan gugatan ke Pengadilan. Bentuk pertanggungjawaban penerbit terhadap penerbitan bilyet giro kosong yaitu memberikan ganti rugi serta memberikan objek jaminan kepada penerima berdasarkan putusan pengadilan.
Perlindungan Hukum Bagi Nasabah Penyimpan Pada Lembaga Keuangan Mikro Syariah
Authors: Jannah Mifthahul , Raffles Raffles , Alissa Evalina 
Published: June 2022

This study aims to indentify and analyze (1) the arrangements regarding the form of legal protection for depositors at Sharia MFIs, (2) the limitations regarding the authority of OJK to depositors at Sharia MFIs. The research method used is juridical normative using a statute approach, conceptual approach and case approach. The results of this research are (1) Regulations regarding the form of legal protection for depositors in the form of preventive protection are clearly contained in the laws regarding MFIs. Meanwhile, repressive protection in the form of dispute resolution is carried out at the Religious Court,and it can be resolved through other means based on the agreement of the disputing parties if it is stated in the agreement. Legal protection regarding depositing customer funds in the form of LPS can be found in Article 19 of the laws regarding MFIs, government regulations that further explain the LPS rules for this Sharia MFIs do not yet exist, so it can be said that this LPS has not yet been formed, (2) The limitations of the OJK's authority are include about regulation, supervision and settlement of Sharia MFIs, especially in terms of solvency and liquidity difficulties which are assisted by the Regency/City Government or other appointed parties. Furthermore, the Ministry of Cooperatives conducts the inspection with the Ministry of Internal Affairs and OJK on Sharia MFIs in terms of licensing and guidance.
Abstrak
Penelitian ini bertujuan untuk mengetahui dan menganalisis (1) pengaturan mengenai bentuk perlindungan hukum bagi nasabah penyimpan pada LKM Syariah, (2) batasan mengenai kewenangan OJK kepada nasabah penyimpan pada LKM Syariah. Metode penelitian yang digunakan adalah yuridis normatif dengan menggunakan pendekatan perundang-undangan (statute approach), pendekatan konseptual (conceptual approach) dan pendekatan kasus (case approach). Hasil dari penelitian ini adalah (1) Pengaturan mengenai bentuk perlindungan hukum nasabah penyimpan berupa perlindungan preventif sudah secara jelas terdapat pada undang-undang mengenai LKM. Sedangkan perlindungan represif berupa penyelesaian sengketa dilakukan di Pengadilan Agama, dapat diselesaikan melalui cara lain berdasarkan kesepakatan para pihak yang bersengketa bila dicantumkan pada perjanjian. Perlindungan hukum mengenai dana nasabah penyimpan berupa LPS dapat ditemukan pada undang-undangan mengenai LKM Pasal 19, peraturan pemerintah yang menjelaskan lebih lanjut mengenai aturan LPS pada LKM Syariah ini belum ada sehingga dapat dikatakan bahwa LPS ini belum dibentuk, (2) Batasan kewenangan OJK diantaranya mengenai pengaturan, pengawasan serta penyelesaian terhadap LKM Syariah terutama dalam hal kesulitan solvabilitas dan likuiditas yang dibantu oleh Pemerintah Daerah Kabupaten/Kota atau kepada pihak lain yang ditunjuk. Sedangkan Kementerian Koperasi melakukan pemeriksaan bersama-sama dengan Kementerian Dalam Negeri dan OJK pada LKM Syariah dalam hal perizinan dan pembinaannya.