bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlation of White Blood Cells Level in Semen with Endometritis in Subfertile Couples
Authors: Lie Vellyana 
Published: December 2022

Introduction
Over the past decades, infertility has become a serious health problem worldwide and until nowadays numerous studies have shown it can be a negative prognostic factor for infertility.1 During, natural intercourse, ejaculation of seminal fluid into vagina may deposit spermatozoa, contaminants, and bacteria into the uterus by pelvic or penile thrusting and belling of the glans penis during coitus. In that case, the risk factor of infection in both women and man will happen post natural intercourse. So, the relationship between endometritis and increasing white blood cells level in sperm with infertility such as repeated implantation failure and recurrent miscarriage has recently emerged as an area of inquiry.
Aims
Aims this study, Correlation of endometritis that found in hysteroscopy examination and increasing white blood cell level in semen in sub fertile couples.
Methods
This study was conducted from 492 Infertility couple who underwent hysteroscopy from January 2021 to December 2021. The semen analysis was performed at least twice with range two weeks one from the other based on WHO guideline. Hysteroscopy was performed during endometrial proliferation phase. All data analysis performed using IBM SPSS 23.
Results
The result showed that mean leucocyte level range difference was significant in patient non-endometritis was 0.25 and endometritis patient was 0.66. The leucocyte number had correlation with the result of the pH level and slow progressive motility in semen specimen.
Conclusion
This research result showed the correlation women with resulted endometritis in hysteroscopy and white blood cell in semen specimen and had correlation with pH level and slow progressive motility in semen specimen.
Keywords: White blood cells count in semen, endometritis, subfertil.
ANALISIS TRAVEL COST DAN MANFAAT TAMAN HUTAN HUJAN TROPIS INDONESIA (TH2TI) BAGI MASYARAKAT
Authors: Rahman Muhammad Arif , Fithria Abdi , Nisa Khairun 
Published: December 2022

This study aims to analyze the economic value of the Indonesian Tropical Rain Forest Park TH2TI using the Travel Cost Method and to find out the economicand social benefits for the surrounding community. This research was conducted in Banjarbaru City, South Kalimantan for 2 months. The resultsof the study indicate that the costof traveling at the TH2TI location is influenced by the distance of each end as well as the means of transportation and consumption of visitors. The data above is for the location of the closest visitor position, namely Banjarbaru with an estimated distance of 7 km with an average expenditure per person of Rp. 29,000, Martapura/ Banjar a distance of 10 km the average expenditure is Rp. 30.000, Tanah Laut a distance of 55 km with an average expenditure of Rp. 70,000 and the furthest is a new city with a distance of 300 km with an average expenditure of Rp. 400,000. The influence of the presence of TH2TI on the socio-economic conditions of the community is as follows, providing employment Opportunities for the community around MH2T are business opportunities both as traders and in the service sector. In tourism in Cempaka Village, namely Ungu Lake, the development strategy for Purple Lake from the results of the analysis of internal and external factors for Purple Lake, namely 1.95 and 1.75, which is in quadrant II, this position shows solid but faces great difficulties. The Purple Lake site design uses a tourism concept that provides a variety of tours in one tourist locationPenelitaian ini dimaksudkanr untuk menganalisis nilai ekonomi Taman Hutan Hujan Tropis Indonesia TH2TI dengan metode Travel Cost Method serta mengetahui manfaat ekonomi dan sosial bagi masyarakat sekitar. Penelitian ini dilakukan di Kota Banjarbaru, Kalimantan Selatan Selam 2 bulan. Hasil penelitian menujukan bahwa biaya di dalam perjalan pada lokasi TH2TI, di pengaruhi oleh jarak masing masing pengujung serta alat transportasi dan konsumsi pengunjung. Data diatas untuk lokasi kedudukan pengunjung paling terdekat yaitu Banjarbaru dengan jarak estimasi 7 km dengan rata-rata pengeluaran per orang Rp. 29.000, Martapura/ Banjar jarak 10 km rata-rata pengeluaran Rp. 30.000, Tanah laut jarak 55 km rata-rata pengeluaran Rp.70.000 dan yang paling terjauh yaitu kota baru dengan jarak 300 km rata-rata pengeluaran Rp. 400.000. Pengaruh kehadiran TH2TI terhadap sosial ekonomi masyarakat, tersedianya lapangan pekerjaan berpeluang bagi masyarakat. TH2TI adalah peluang usaha baik sebagai pedagang maupun bidang jasa. didalam wisata yang terdapat di Kelurahan Cempaka yaitu Danau Ungu, Strategi pengembangan untuk Danau Ungu dari hasil analisis faktor internal dan eksternal Danau Ungu yaitu 1,95 dan 1,75 yang Berada di kuadran II posisi ini menunjukkan solid namun menghadapi kesulitan besar. Desain tapak Danau Ungu menggunakan konsep wisata yang memberikan beragam wisata di dalam satu lokasi wisata.
The Use of Kahoot in Writing Skills in Junior High School
Authors: Romatullah Sitti , Santoso Dian Rahma 
Published: December 2022

Writing skill is a way to express and build the ideas into written form. In 4.0 era, which technology is to support the education, one of which is by using Kahoot in learning process. The methodology used in this research was the experimental quantitative research with the paired sample t-test. The research population was 319 eigh grade students. Then, the research sample was 8E consisting of 36 students at SMPN 3 Sidoarjo in the academic year of 2021/2022. The result of the data presented that, there was significant different score between pre-test and post-tes. The mean pre-test was 54.25 and the the mean of post-test was 68.78. The significant value of the research was 0.000 < significant level 0.05. therefore, it showed there is an effect of Kahoot for learning writing skill recount text of the eight grade students at SMPN 3 Sidoarjo
Development of Marketing in the Context of A Tourism Pandemic in Uzbekistan
Authors: Ramazonovma Muhammadova Dilovar 
Published: December 2022

The article analyzes the basic foundations of marketing in tourism. The author analyzes the methodology of tourism marketing, which is relevant in the current market conditions after the Pandemic. Based on theoretical materials and practical research by leading scientists in this field, as a result of the article, conclusions were drawn regarding the development of tourism in tourism at the informatization of society and globalization of the market in Uzbekistan. The paper formulates specific areas of current research in tourism marketing for the pandemic period.
Furthermore, the article discusses the conceptual foundations of marketing in the tourism industry, its features, functions, the need to use modern information technologies.
Reorganization of Northern Peri-Gondwanan Terranes at Cambrian–Ordovician Times: Insights from the Detrital Zircon Record of the Ossa-Morena Zone (SW Iberian Massif)
Authors: Accotto Cristina , Azor Antonio , Martínez Poyatos David , Pedrera Antonio , González Lodeiro Francisco 
Published: December 2022

AbstractThe Ossa-Morena Zone constitutes a fringe Gondwana-related terrane all along the Paleozoic. This continental block has been classically interpreted as being attached to a portion of the northern Gondwanan margin located close to the West African Craton. We report here the results of U-Pb dating on detrital zircon grains from 15 metasedimentary rocks collected in two well-exposed and well-dated Cambrian sections (Córdoba and Zafra) of the Ossa-Morena Zone. The studied samples show a dominant late Tonian-Ediacaran population peaked at c. 600 Ma. Secondary populations are Rhyacian-early Orosirian and late Orosirian-Statherian in age, with maxima at c. 2.1 and 1.9 Ga. Minor detrital zircon populations are Mesoarchean-early Siderian in age, with peaks between c. 3.05 and 2.45 Ga. Most of the studied samples lack a Stenian-early Tonian population, except for two of them with a minor peak at c. 1 Ga. Our results corroborate previous studies that locate the Ossa-Morena Zone close to the West African Craton and/or the Tuareg Shield (i.e., in a western position with respect to other Variscan zones of the Iberian Massif) at the onset of the rifting stage that opened the Rheic Ocean. Nevertheless, the absence of a significant Stenian-early Tonian population in the Cambrian Ossa-Morena rocks contrasts with the reported results on middle Ordovician-Lower Devonian rocks of this zone, which systematically contain an important population with a peak at c. 1 Ga. We relate this change to the latest Ediacaran-early Ordovician paleogeographic/paleotectonic evolution of the Ossa-Morena Zone, which might have recorded a significant eastward displacement, together with a reorganization of the drainage systems. Thus, the vanishing stages of the Cadomian orogeny could have translated eastward the Ossa-Morena Zone terrane at latest Ediacaran-earliest Cambrian time due to change in plate kinematics from subduction to right-lateral shearing. This translation would have shifted the Ossa-Morena Zone from an Ediacaran location close to the West African Craton to a Cambrian position close to the Tuareg Shield. Finally, the rift-to-drift transition occurred at late Cambrian-early Ordovician time along the northern Gondwanan margin would have reorganized the drainage systems, facilitating sediment supply from an eastern source with abundant Stenian-early Tonian detrital zircon grains, probably the Saharan Metacraton.
Interleukins and the risk of non-alcoholic fatty liver disease: a two-sample Mendelian randomization study
Authors: Wang Fang , Mi Jiarui , Bai Xiaoyin , Ruan Gechong , Zhang Yu , Yu Kang 
Published: December 2022

Abstract
Background and Aims: Interleukins (ILs) are associated with non-alcoholic fatty liver disease (NAFLD), however the direction and causal effects of them susceptibility remain unclear. Two-sample Mendelian randomization (MR) study was performed to investigate the causal relationship.
Materials and Methods: Single nucleotide polymorphisms associated with 10 ILs were used as instrumental variables. Summary-level results of estimates for the associations of NAFLD were obtained from two large multi-centered NAFLD genome-wide association study (2,377 cases and 23,5679 controls). For univariable MR, inverse-variance weighted (IVW) method was applied, while MR-Egger, Weighted Median and MRPRESSO were conducted as sensitivity analyses. Lastly, we performed meta-analyses with estimates from the two cohorts.
Results: IL-1 receptor antagonist (IL-1Ra) demonstrated a suggested significant association with an increased risk of NAFLD in both cohorts, with OR 1.435 (95%CI, 1.041-1.977, P=0.0270) and 1.424 (95%CI, 1.011-2.004, P=0.0430), respectively. The combined estimate OR 1.430 (95%CI, 1.132-1.807, P=0.0027). Furthermore, genetically proxied IL-6 and IL-6 receptor alpha (IL-6Ra) levels displayed consistent positive trend with an increased risk of NAFLD, although none of them reach suggestive significance. Notably, the pooled estimates were 1.827 (95% CI, 1.328-2.514, P=0.0002) for IL-6 and 1.098 (95% CI, 1.026-1.176, P=0.0068) for IL-6Ra, respectively. The sensitivity analysis showed consistent positive trend towards the increased NAFLD susceptibility, though none of them achieved statistical significance.
Conclusion: The results suggested genetically proxied circulating of IL-1Ra, IL-6, and IL-6Ra are causally associated with the risk of NAFLD. Moreover, our data highlights the potential targeted measures and drug repurposing strategies in the NAFLD prevention and treatment.
Resident satisfaction Indicators in long term care settings in the United States: A scoping review
Authors: Li Xiaoli , Mpofu Elias , Yin Cheng 
Published: December 2022

Abstract
Background Due to an increasingly aging population and long-term care available, the number of older adults seeking long-term care facilities is growing. Resident satisfaction indicators have become important measurements of service quality. However, few scoping reviews have investigated the evidence on prevalent resident satisfaction indicators and associated factors. The aim of the study is to summarize the evidence on the types of resident satisfaction indicators utilized in long term care settings in the United States
Methods We searched the PubMed, PsycInfo, AgeLine, MEDLINE, Web of Science for articles that published on resident care satisfaction indicators in long-term care facilities and that published in English language journals from inception to 2021. Following PRSMA guideline, 510 titles and abstracts were screened for relevance.
Results A total of 33 articles provided evidence about the determinants of resident satisfaction in different long-term care settings. The analysis yielded to groups of indicators of resident care satisfaction: multi-factors indicators spanning room, staff, food, care services, activities, laundry, choice, finances, overall rating, and those relating to single factors of resident satisfaction, including facility factor, resident factors, service program factor, food service factor, and staff factor.
Conclusion Most residential care facilities used multifactor indicators for the benefit of comprehensiveness. Single factor indicators tend to be used for getting a clear picture of what specific changes need to be made in certain service area. Combinations of multiple factors and single factors can obtain both a comprehensive satisfaction and detailed information to guide change.
What acceleration data from wildlife collars and animal body mass tell us about seed dispersal
Authors: Buchmann Carsten M. , Dreyling Lukas , Constantin Mihaela , Schurr Frank M. 
Published: December 2022

Abstract
Background: Animals are very important for plant seed dispersal in light of global change. The study of seed transport on the exterior of animals’ bodies (epizoochory) is particularly challenging due to the difficulty to describe and quantify the process of seed release. Shaking movement of fur has been shown to cause seed release and can hence determine seed retention times, necessary to assess dispersal distances. Such information on shaking movements is, however, only available on the neck of animals thanks to wildlife collars containing accelerometers.
Methods: In order to quantify shaking forces on the main body of mammals where most plant seeds attach, and to predict this body acceleration from (known) neck acceleration, we simultaneously measured acceleration at the neck, the breast and the upper hind leg of mammals spanning a large range of body masses. We quantify shaking strength as the 95%-quantile of the resultant acceleration (of all measured values in data subsections of five seconds).
Results: While, compared to the neck, acceleration had a similar range of values at the breast and was considerably higher at the leg, neck acceleration in combination with animal body mass proved to be a very valuable predictor: 81 and 63% of variation in breast and leg acceleration could be explained, respectively.
Conclusions: These results enable the use of available acceleration data from animals’ necks to predict body acceleration for mammals with known body mass. In combination with i) further lab experiments to determine seed release in dependence of fur acceleration for specific seed-fur combinations, and ii) animal movement data, this information can be used to predict probability and spatial distributions of seed dispersal. Besides seed dispersal, we believe that the ability to predict body acceleration on mammals should also benefit other ecological fields like parasitology.
Spatial patterns and the associated factors for breast cancer hospitalization in Fujian Province, China
Authors: Song Mengjie , Huang Xiaoxi , Wei Xueqiong , Tang Xuwei , Rao Zhixiang , Hu Zhijian , Yang Haomin 
Published: December 2022

Abstract
Background
Despite the known increasing incidence of breast cancer in China, evidence on the spatial pattern of hospitalization for breast cancer is scarce. This study aimed to describe the disparity of breast cancer hospitalization in Southeast China and to explore the impacts from socioeconomic factors and heavy metal pollution in soil.
Methods
This study was conducted using the New Rural Cooperative Medical Scheme (NRCMS) claims data covering 25.52 million female rural residents from 73 counties in Southeast China during 2015–2016. The associations between breast cancer hospitalization and socioeconomic factors and soil heavy metals pollutants were evaluated with quasi-Poisson regression models and geographically weighted Poisson regressions (GWPR).
Results
The annual hospitalization rate for breast cancer was 101.40/100,000 in the studied area and the rate varied across different counties. Overall, hospitalization for breast cancer was associated with road density (β = 0.43, P = 0.02), urbanization (β = 0.02, P = 0.002) and soil cadmium (Cd) pollution (β = 0.01, P = 0.02). In the GWPR model, a stronger spatial association of Cd, road density and breast cancer hospitalization was found in the northeast regions of the study area while breast cancer hospitalization was mainly related to urbanization in the western regions.
Conclusions
Soil Cd pollution, road density, and urbanization were associated with breast cancer hospitalization in different regions. Findings in this study might provide valuable information for healthcare policies and intervention strategies for breast cancer.
Factors Influencing Sexual and Reproductive Health-related Misuse of Digital Media in Bangladesh
Authors: BakiBillah Abul Hasan , Chowdhury ABM Alauddin , Hamid Syed Abdul 
Published: December 2022

Abstract
This study explored factors influencing the sexual and reproductive health-related misuse of digital media in Bangladesh. The study adopted Key-Informant-Interview (KII) among the Nineteen (19) relevant key informants including academicians, researchers, policymakers, and activists. The thematic analysis of the transcripts was carried out. The mean age of the informants was 40 (SD+/- 6.8) years with having a minimum level of a bachelor degree. Easy access to indecent (porn) sites, low self-awareness of the girls in using social networking sites and other digital devices, the culture of injustice and muscle-men phenomenon, parent’s negligence, and the level of awareness were found as the major factors behind the misuse of digital media in the form of cyber-bullying, sexting, revenge porn, sextortion, access to and production of porn videos, etc. This study revealed that women and girls are the prime victims of the misuse where the worst form of victimization is to lead a deplorable life as a sex-slave and persist with chronic mental disorders. The study recommended that the complete ban on provocative indecent websites, high level of awareness among the women and girls, seeking immediate help from the law-enforcement agencies, and importantly, parents’ full-fledged care and attention.
Bright Semiconductor Single-Photon Sources Pumped by Heterogeneously Integrated Micropillar lasers with Electrical Injections
Authors: Liu Jin , Li Xueshi , Liu Shunfa , Wei Yuming , Ma Jiantao , Song Changkun , Yu Ying , Su Rongbin , Geng Wei , Ni Hai-Qiao , Liu Hanqing , Su Xiangbin , Niu Zhichuan , Chen You-Ling 
Published: December 2022

Abstract
The emerging hybrid integrated quantum photonics combines advantages of different functional components into a single chip to meet the stringent requirements for quantum information processing. Despite the tremendous progress in hybrid integrations of III-V quantum emitters with silicon-based photonic circuits and superconducting single-photon detectors, on-chip optical excitations of quantum emitters via miniaturized lasers towards single-photon sources (SPSs) with low power consumptions, small device footprints and excellent coherence properties is highly desirable yet illusive. In this work, we present realizations of bright semiconductor singe-photon sources heterogeneously integrated with on-chip electrically-injected microlasers. Different from previous one-by-one transfer printing technique implemented in hybrid quantum dot (QD) photonic devices, multiple deterministically coupled QD-circular Bragg Grating (CBG) SPSs were integrated with electrically-injected micropillar lasers at one time via a potentially scalable transfer printing process assisted by the wide-field photoluminescence (PL) imaging technique. Optically pumped by electrically-injected microlasers, pure single photons are generated with a high-brightness of a count rate of 3.8 M/s and an extraction efficiency of 21.5%. Such a high-brightness is due to the enhancement by the cavity mode of the CBG, which is confirmed by a Purcell factor of 2.5. Our work provides a powerful tool for advancing hybrid integrated quantum photonics in general and boosts the developments for realizing highly-compact, energy-efficient and coherent SPSs in particular.
Simulation of inertial droplet dispersion and the spray mediated fluxes in the atmospheric boundary layer above waved water surface: a Lagrangian stochastic model versus direct numerical simulation
Authors: Troitskaya Yuliya , Druzhinin Oleg , Gladskikh Daria , Ermakova Olga , Soustova Irina 
Published: December 2022

Abstract
Lagrangian stochastic models (LSM) are widely used to model the dispersion of sea spray droplets injected from the water surface into the marine atmospheric boundary layer (MABL) and for evaluation of the spray impact on the exchange fluxes between the atmosphere and the ocean. While moving through the MABL the droplets pass through the region of high gradients of air velocity, temperature and humidity occurring in the vicinity of the air-water interface. In this case, the applicability of LSMs constructed under the assumption of weakly inhomogeneous flows is questionable. In this work, we develop a Lagrangian stochastic model taking into account the strongly inhomogeneous structure of the airflow in MABL and, in particular, the anisotropy of turbulence dissipation rate. The model constants and the diffusion matrix coefficients are calibrated by comparison of the LSM prediction for the profiles of droplet concentration and the exchange fluxes of sensible and latent heat against the results of direct numerical simulation (DNS) of turbulent, droplet-laden airflow over a waved water surface.
CSF tau phosphorylation at T217 and T205 are improved biomarkers of amyloid and tau pathology in Alzheimer disease
Authors: Barthélemy Nicolas , Saef Benjamin , Li Yan , Gordon Brian , He Yingxin , Horie Kanta , Stomrud Erik , Salvado Gemma , Janelidze Shorena , Sato Chihiro , Ovod Vitaliy , Henson Rachel , Fagan Anne , Benzinger Tammie , Xiong Chengjie , Morris John , Hansson Oskar , Bateman Randall , Schindler Suzanne 
Published: December 2022

Abstract

CSF Aβ42/Aβ40 and tau phosphorylated at site 181 (p-tau181) are well-established biomarkers of Alzheimer disease (AD). This study used mass spectrometry to measure concentrations of 9 phosphorylated and 5 non-phosphorylated species, and phosphorylation occupancies (phosphorylated/non-phosphorylated [%]) at 10 sites. In 750 individuals with a median age of 71.2 years, CSF pT217/T217 (%) predicted amyloid PET status slightly better than Aβ42/Aβ40 (p=0.02). In amyloid PET positive individuals (n=263), CSF pT217/T217 (%) was more strongly correlated with amyloid PET Centiloid (Spearman ρ=0.69) than Aβ42/Aβ40 (ρ = -0.42, p<0.0001). CSF pT217/T217 (%) and pT205/T205 (%) were superior to Aβ42/Aβ40 and similar to tau PET in prediction of cognitive impairment. In two independent cohorts with symptomatic AD (n=55 and n=90), CSF pT217/T217 (%) and pT205/205 (%) were better correlated with tau PET measures than CSF p-tau181 concentration. CSF pT217/T217 (%) and pT205/205 (%) represent improved CSF biomarkers of amyloid and tau pathology in AD.