bluuebunny/crossref_metadata_2025_split huggingface dataset:
Post COVID-19 recovery for independent full-service restaurants using the salience theory: what will it take to get customers to return?
Authors: Sun Xiaodi , Ge Li , Marvil Charles 
Published: June 2022

Purpose
This study aims to compare customers’ perceived importance of various post-COVID-19 recovery strategies (i.e. sanitary practices, discounts, menu modification and marketing strategies) adopted by independent full-service restaurants (casual dining versus upscale/fine dining) using the salience theory. It also assesses the associations between customers’ perceptions and their restaurant spending patterns.

Design/methodology/approach
An online survey was administered to assess 657 US adult participants’ restaurant spending behaviors at different stages of the COVID-19 pandemic using recall questions. Higher-spending versus lower-spending participants’ perceived importance of restaurant recovery strategies were compared in the casual dining versus upscale/fine dining contexts.

Findings
Amid the COVID-19 pandemic, sanitary practices were the most important factor in participants’ restaurant choices, and it was more important for independent casual dining restaurants than for upscale/fine dining restaurants. No significant difference was found in participants’ perceived importance of sanitary practices across different geographic regions. Higher-spending diners (HSD) perceived almost every restaurant recovery strategy as important. Lower-spending diners (LSD) only considered sanitary practices as important.

Practical implications
This study identified important strategies that restaurant operators and public health officials can adopt to help full-service restaurants recover from pandemic losses.

Originality/value
This study differs from previous consumer choice studies; in that it compared HSD with LSD regarding their perceived importance of various restaurant recovery strategies. This study also provides new insights for understanding the salience theory of choice under the impact of COVID-19.
Safety of a 24‐h‐or‐less break‐in period in elderly patients undergoing urgent‐start peritoneal dialysis: A multicenter retrospective cohort study
Authors: Cheng Siyu , Yang Liming , Sun Zhanshan , Zhang Xiaoxuan , Zhu Xueyan , Meng Lingfei , Guo Shizheng , Zhuang Xiaohua , Luo Ping , Cui Wenpeng 
Published: June 2022

AbstractBackgroundSeveral elderly patients with end‐stage renal disease (ESRD) had to undergo urgent‐start peritoneal dialysis (USPD). This study aimed to determine whether break‐in period (BI) within 24 h was feasible in elderly patients undergoing USPD.MethodsPatients with ESRD who underwent PD at five hospitals were screened. Patients were divided into the BI ≤24 h and >24 h groups. Complications were compared between the two groups. Multivariate logistic regression model was used to determine whether BI ≤24 h was associated with complications.ResultsA total of 175 elderly patients were included: BI ≤24 h group, 78; and BI >24 h group, 97. There was no significant difference in the rate of complications between the two groups (all p > 0.05). Furthermore, BI ≤24 h was not an independent risk factor for complications (all p > 0.05).ConclusionsStarting PD within 24 h after PD catheter insertion was feasible in elderly ESRD patients.
Alcohol misuse in patients with alcohol‐related liver disease: How can we do better? A narrative review of the literature
Authors: Horrell Jane , Callaghan Lynne , Dhanda Ashwin 
Published: June 2022

AbstractBackgroundOngoing alcohol use is strongly associated with progressive liver damage and higher mortality in patients with alcohol‐related liver disease (ArLD). Reduction in alcohol use is therefore the cornerstone of treatment to improve the long‐term outcome of these patients. However, a large proportion of patients continue to use alcohol and do not access or engage with alcohol treatment services after a diagnosis of ArLD. We reviewed the literature on factors associated with ongoing alcohol consumption among patients with ArLD to identify barriers or facilitators to their accessing alcohol treatment.MethodsA search of MEDLINE and EMBASE was conducted using search strategies relating to ArLD and the psychosocial factors hypothesized to influence alcohol reduction and/or abstinence.ResultsThere were few relevant studies pertinent to this population group. Several studies reported a high prevalence of mental health diagnoses associated with the severity of alcohol dependence. Social and environmental factors were shown to be important determinants of alcohol use. Common themes perceived as barriers to treatment from qualitative interviews with ArLD patients across studies included poor communication between the clinical team and patient, lack of symptoms recognized by patients themselves, and perceived loss of control over their condition.ConclusionsWe recommend that future clinical studies of patient cohorts with ArLD include detailed psychosocial assessments to capture information on mental health and social factors. Qualitative studies are required to explore the patient journey pre and post hospital admission, which should focus on identifying facilitators and barriers to accessing treatment. Well‐designed, controlled studies are needed to identify patient, social, and environmental factors associated with relapse to alcohol use after a diagnosis of ArLD. These data will enable us to adapt our support for patients to enhance engagement with services and improve long‐term outcomes.
Perceptions of rural high school teachers ‐ on the frontline of youth suicide
Authors: Bowman Siann , McKinstry Carol , Howie Linsey , Hepworth Graham , McGorry Patrick 
Published: June 2022

AbstractObjectiveThis study aimed to investigate the perceptions and beliefs of rural high school teachers about student suicide completion in their school and their perceived self‐efficacy in identification of suicidality in students (suicidal ideation, plans and behaviours).DesignA cross‐sectional survey methodology.SettingGippsland and the Loddon Mallee regions of Victoria, Australia.ParticipantsRural high school teachers.Outcome MeasureA survey that aimed to obtain participants' perceptions and self‐reports about students who had died by suicide in their school within the last 5 years, their perceived self‐efficacy in identifying suicidal students and barriers to helping students at risk.ResultsTwo hundred and seventy‐seven rural high school teachers participated and 86% reported that a student from their school had died by suicide within the last 5 years. Sixty‐five per cent believed that more than one student had died by suicide and 70% perceived they were currently aware of students experiencing suicidality in their class. Receiving professional development about suicide and obtaining help from mental health clinicians predicted perceived self‐efficacy in identification of suicidality in students. Participants perceived the barriers to help students at risk included insufficient numbers of school‐based mental health professionals and community mental health services.ConclusionsMany rural high school teachers perceive they are at the front line of the youth suicide crisis due to unmet service need in youth mental ill health. Increased access to effective services immediately after teachers become aware of suicidality may assist in reducing youth suicide in rural areas.
Dump Truck Destiny: Alberta Oil, “East Coast” Workers, and Attachment to Extraction
Authors: Mazer Katie 
Published: June 2022

AbstractThis paper considers how white, rural, working‐class men come to be seen, by employers and themselves, as a “natural fit” for mobile work in resource extraction. Examining mobility between eastern Canada and the Alberta petroleum industry, I trace longstanding racial, geographical, and gendered explanations of these workers as dependent and averse to work. I draw on interviews with employers, employment counsellors, and mobile workers, and media representations to consider how these narratives function to shape and constrain workers’ political imaginaries and understandings of themselves. The pervasive story of these workers as undeserving has enabled the emergence of a contrasting working subject: the hard‐working, flexible “east coast” worker who is a natural fit for mobile work in resource extraction. I argue that, despite the challenges of mobile resource work, the interplay of stories that pathologise and celebrate these workers has encouraged their attachment to resource extraction as the pathway to a better life.
Riot Platforms: Protest, Police, Planet
Authors: liu michelle corinne , Brenes Reyes Jaime R. , Sahoo Sananda , Dyer‐Witheford Nick 
Published: June 2022

AbstractA wave of urban uprisings swept the planet from 2018 to 2021, throwing protesters into violent collisions with police, confrontations fought out both in the streets and on digital platforms. This paper proposes successive cycles of digitally‐mediated social unrest are passing into a phase marked by protesters’ assemblage of “riot platforms”. It examines the development of such platforms by movements in France, Hong Kong, Chile, Lebanon, Ecuador and elsewhere, and the responses of a police power which is itself increasingly digitalised, examines how these contending dynamics played out in 2020 Black Lives Matter rising, discusses the alt‐right’s Capitol Hill seizure as a digitally‐organised reactionary counter‐riot, and concludes by situating “riot platforms” in planet‐wide processes of political recomposition.
IMPACT study: Impact of adherence to anti‐VEGF intravitreal injections for macular disease during COVID 19‐related confinement in France
Authors: Hurand Victoire , Ducloyer Jean‐Baptiste , Baudin Florian , Aho Serge , Weber Michel , Kodjikian Laurent , Devin François , Gabrielle Pierre‐Henry , Creuzot‐Garcher Catherine , Massin Pascale ,   for the CFSR Research Net
Published: June 2022

AbstractPurposeThe aim of this study was to evaluate the impact of adherence to French coronavirus disease 2019 (COVID 19)‐related guidelines for intravitreal injection (IVI) practice on the visual outcomes of patients treated with anti‐vascular endothelial growth factor (VEGF) agents for macular diseases during the first lockdown period.MethodsObservational multicentre study including all patients from 18 centres with an IVI initially planned during the lockdown. Visual acuity (VA, ETDRS) was recorded at 1 and 4 months after lockdown. French COVID 19‐related guidelines recommended maintaining IVI practice. We defined three groups of patients: A, adherent to guidelines; NA+, non‐adherent with delayed IVIs; and NA−, non‐adherent without IVIs performed during the lockdown. Risk factors for non‐adherence and visual loss were studied.ResultsA total of 3020 eyes of 3020 patients, aged 77.8 ± 11.6 years, 59.8% women, were included. 59.3% were non‐adherent(46.7% NA+, 12.6% NA−). A smaller decrease in VA at 4 months was observed in the A group than the NA+ and NA− group (−0.2 ± 6.7, −0.3 ± 6.9 and −1.5 ± 6.9, respectively [p < 0.001]). Factors associated with non‐adherence were in multivariable analysis, older age, hospital practice, low‐density population areas, high viral incidence areas, longer intervals between injection and treat and extent protocol. Factors associated with visual loss at 4 months in multivariable analysis were, being in the NA− group, older age, T&E and fixed regimens.ConclusionStrict adherence to guidelines was associated with better visual outcome, although most of our patients did not attend as planned. Identification of patients at risk could help in the future in case of a new pandemic lockdown.
Creating stories for impact: Co‐producing knowledge with young people through story mapping
Authors: van Blerk Lorraine , Hunter Janine , Shand Wayne , Prazeres Laura 
Published: June 2022

AbstractThis paper explores co‐production of knowledge for impact with young people through the process of creating digital story maps, drawing on co‐produced research from two projects: with homeless youth in African cities; and with youth refugees in Uganda and Jordan. It examines the process of creating three story maps with the intention of enabling young people to co‐produce knowledge exchange and research impact. Participants were able to engage in the latter stages of research as part of research analysis, outcomes and outputs beyond the temporal and spatial confines of data collection. The story maps were therefore used not only to ‘bring life’ to reports produced for stakeholders and funders, but also to take young people's research stories beyond locally bound contexts to reach a variety of global audiences. The reflections in this paper also highlight that while the approach adopted was not without challenges, in all three story maps a knowledge exchange process was fostered that resulted in young people feeling they had been listened to; were able to contribute to debates that affect their own lives and to instil a desire to create change, influence policy and inform publics about their lives. The paper concludes that story mapping is a useful creative process for extending young people's input into knowledge exchange and longer‐term research impacts.
Hartman's quandary: Reconciling pluralism and realism for virtue ethics in business
Authors: Bhuyan Nisigandha , Chakraborty Arunima 
Published: June 2022

AbstractThere is considerable consensus on the idea that Aristotelian virtue ethics advocates moral realism. In numerous works, the well‐known business ethicist Edwin Hartman grapples with reconciling the unitary vision of life that a particular kind of moral realism advocates and the pluralist respect for diverse cultures and belief systems that comprise our world. This paper closely follows Hartman's efforts to reconcile his liberal values with his guarded support for Aristotelian moral realism. We argue that the realist interpretation of Aristotle's function argument can be employed to strengthen Hartman's critique of the concept of Homo economicus, which is often posited by its proponents and critics alike as the only viable position for a business manager. Drawing from Aristotle, the paper posits a novel notion of species‐excellence as the ultimate telos of human life and an objective basis for a critique of Homo economicus.
Cerebral sinovenous thrombosis associated with head/neck infection in children: Clues for improved management
Authors: Narcy Lucie , Durand Sabine , Grimaud Marion , Leboucq Nicolas , Grevent David , Cambonie Gilles , Couloigner Vincent , Rivier François , Meyer Pierre , Kossorotoff Manoelle 
Published: June 2022

AbstractAimTo compare paediatric patients with cerebral sinovenous thrombosis (CSVT) with and without head/neck infection to improve management of the condition.MethodWe conducted a bicentric retrospective study of consecutive children (neonates excluded) with radiologically confirmed CSVT, comparing children with a concurrent head/neck infection and children with other causes.ResultsA total of 84 consecutive patients (46 males and 38 females) with a median age of 4 years 6 months (range 3 months–17 years 5 months) were included. Associated head/neck infection was identified in 65.4% of cases and represented the main identified CSVT aetiology. Children in the head/neck infection group displayed a milder clinical presentation and less extensive CSVT. Median time to complete recanalization was significantly shorter in this group (89 days [interquartile range 35–101] vs 112.5 days [interquartile range 83–177], p = 0.005). These findings were even more pronounced in the subgroup of patients with otogenic infection and no neurological sign.InterpretationAs CSVT in the setting of an otogenic infection and no neurological sign seems to represent a milder condition with a shorter course, these results suggest adapting current recommendations: consider earlier control imaging in paediatric otogenic CSVT, and shorter anticoagulant treatment if recanalization is obtained.What this paper adds

Children with cerebral sinovenous thrombosis related to head/neck infections have a milder clinical presentation.
They also have a shorter recanalization time, especially if there is otogenic infection without neurological symptoms.
Functional characterization of Melampsora larici‐populina Hog1‐type MAPK in response to osmotic stress
Authors: Yu Dan , Yang Bing , Chen Kaiyue , Liu Yifei 
Published: June 2022

AbstractThe obligate biotrophic pathogen Melampsora larici‐populina, responsible for poplar foliar rust disease, causes annual epidemics and severe damages to poplar plantations worldwide. Flexible responses to external osmotic pressure changes are important for the growth and survival of pathogens. In a previous study, we suggested that the Hog1‐type MAPK MlpHog1 in M. larici‐populina may play a role in infectious growth and responses to various environmental stresses. In the present study, we analysed its biological characteristics. MlpHog1 displayed a conserved coding sequence pattern among five strains from different regions of China. MlpHog1 restored the Hog1‐orthologue mutant defects responding to hyperosmotic stress in both Saccharomyces cerevisiae and Magnaporthe oryzae. Transient expression in wheat protoplasts revealed that MlpHog1 is localized in the cytoplasm and nucleus. These results indicate that MlpHog1 plays a positive role in responding to osmotic stress in the poplar rust M. larici‐populina.
UK dental students' ability and confidence in applying the Index of Orthodontic Treatment Need and determining appropriate orthodontic referral
Authors: Bouskandar Sherouq Yousif , Al Muraikhi Lina , Hodge Trevor M. , Barber Sophy K. 
Published: June 2022

AbstractIntroductionThe aim was to assess the ability and confidence of UK undergraduate dental students in applying the Index of Orthodontic Treatment Need (IOTN) and determining appropriate orthodontic referral.Materials and MethodsThis was a cross‐sectional survey using a case‐based online questionnaire. Fourth and fifth year undergraduate dental students were recruited from UK dental schools through their university and social media. Six cases were presented and participants were asked to provide an IOTN score and judgement about referral. Participants were asked about their confidence, experience and orthodontic teaching.ResultsSixty‐nine responses were returned. A quarter of participants reported having used IOTN before in a clinical setting. Clinical experience with IOTN influenced confidence. Familiarity with making orthodontic referrals was low and only one participant reported having made an orthodontic referral. Correct IOTN scores were given by 68% of participants for a large 14 mm overjet (5a) case, 43% of participants for an impacted canine (5i) case and 26% of participants for an impacted premolar (5i) case. Incorrect IOTN was most common in hypodontia cases with only 19% correctly identifying mild hypodontia (4h) and 28% identifying severe hypodontia (5h). For the majority of cases, incorrect answers about referral were due to confusion between specialist practitioner and orthodontic consultant pathways.ConclusionsDental students' ability and confidence in correctly applying the IOTN Dental Health Component and selecting the appropriate referral pathway was inadequate. Responses suggest a lack of clinical experience in assessing patients, applying the IOTN and making referrals. The low response rate is disappointing and limits the scope for making recommendations.
Suppression of phosphodiesterase IV enzyme by roflumilast ameliorates cognitive dysfunction in aged rats after sevoflurane anaesthesia via PKA‐CREB and MEK/ERK pathways
Authors: Liu Peirong , Wang Juan , Peng Sheng , Zhang Dan , Zhuang Lin , Liu Chunliang , Zhang Yu , Shi Xiaowei 
Published: June 2022

AbstractPostoperative cognitive dysfunction (POCD) is a prevalent disorder after anaesthesia in the elderly patients. Roflumilast (RF), a phosphodiesterase 4 (PDE‐4) inhibitor, could improve cognition with no side effects. Here, we sought to explore the efficacy of RF in the improvement of cognitive dysfunction caused by sevoflurane (Sev). Sprague–Dawley rats were anaesthetized, and the hippocampal neurons were treated with Sev to develop in vivo and in vitro POCD models, followed by RF administration. The mechanism of the PKA‐CREB and MEK/ERK pathways in the pathogenesis of POCD was explored. Sev impaired the cognitive functions of rats, significantly reduced cyclic adenosine monophosphate (cAMP) concentrations and blocked the PKA‐CREB and MEK/ERK pathways. Moreover, the Sev‐treated rats and neurons exhibited enhanced apoptosis and reactive oxygen species (ROS). After treatment with RF, rats had better learning and memory function, and the activity of neurons in hippocampus and cortex was improved. Loss‐of‐function assay indicated that PKA‐CREB and MEK/ERK signalling impairment reduced cAMP levels and promoted apoptosis and ROS in rat hippocampus and neurons. Generally, RF promotes neuronal activity in rats after Sev treatment by maintaining cAMP levels and sustaining the activation of PKA‐CREB and MEK/ERK pathways. This might offer novel sights for POCD therapy.
The Seizure‐Associated Genes Across Species (SAGAS) database offers insights into epilepsy genes, pathways and treatments
Authors: Gracie Lara , Rostami‐Hochaghan Danial , Taweel Basel , Mirza Nasir ,   the SAGAS Scientists' Collaborative
Published: June 2022

AbstractObjectiveDecades of genetic studies on people with many different epilepsies, and on many nonhuman species, using many different technologies, have generated a huge body of literature about the genes associated with seizures/epilepsy. Collating these data can help uncover epilepsy genes, pathways, and treatments that would otherwise be overlooked. We aimed to collate and structure these data into a database, and use the database to identify novel epilepsy genes and pathways, and to prioritize promising treatments.MethodsWe collated all the genes associated with all types of seizures/epilepsy in all species, and quantified the supporting evidence for each gene, by manually screening ~10 000 publications, and by extracting data from existing databases.ResultsThe largest published dataset of epilepsy genes includes only 977 genes, whereas our database (www.sagas.ac) includes 2876 genes, which demonstrates that the number of genes that can potentially contribute to seizures/epilepsy is much higher than previously envisaged. We use our database to identify 12 hitherto unreported polygenic epilepsy genes, 479 high‐confidence monogenic epilepsy genes, and 394 more biological pathways than identified using the previously largest epilepsy gene dataset. We use a unique feature of Seizure‐Associated Genes Across Species—the number of citations for each gene—to demonstrate that a drug is more likely to affect seizures if there is more evidence that the genes it affects are associated with seizures, and we use these data to identify promising candidate antiseizure drugs.SignificanceThis database offers insights into the causes of epilepsy and its treatments, and can accelerate future epilepsy research.
Artificial intelligence of medical things for disease detection using ensemble deep learning and attention mechanism
Authors: Djenouri Youcef , Belhadi Asma , Yazidi Anis , Srivastava Gautam , Lin Jerry Chun‐Wei 
Published: June 2022

AbstractIn this paper, we present a novel paradigm for disease detection. We build an artificial intelligence based system where various biomedical data are retrieved from distributed and homogeneous sensors. We use different deep learning architectures (VGG16, RESNET, and DenseNet) with ensemble learning and attention mechanisms to study the interactions between different biomedical data to detect and diagnose diseases. We conduct extensive testing on biomedical data. The results show the benefits of using deep learning technologies in the field of artificial intelligence of medical things to diagnose diseases in the healthcare decision‐making process. For example, the disease detection rate using the proposed methodology achieves 92%, which is greatly improved compared to the higher‐level disease detection models.