bluuebunny/crossref_metadata_2025_split huggingface dataset:
Indications, clinical outcome and survival of rotating hinge total knee arthroplasty in a retrospective study of 63 primary and revision cases
Authors: Hecker Andreas , Pütz Hans-Jürg A. , Wangler Sebastian , Eberlein Sophie C. , Klenke Frank M. 
Published: August 2022

Abstract
Purpose
The purpose of this study is to report and compare outcome data of both primary and revision cases using a rotating hinge knee (RHK) implant.

Methods
This study retrospectively analyzed 63 cases (19 primary, 44 revisions) at a mean follow-up of 34 ± 8 months after RHK implantation. Outcome parameters were stability, range of motion (ROM), loosening, Hospital of Special Surgery Score (HSS), Knee Society Score (KSS), Oxford Knee Score (OKS), EQ-5D-3L, and Visual Analog Scale (VAS) for overall function. Revision rates and implant survival are reported.

Results
Eleven percent showed medio-lateral instability < 5 mm, a mean ROM of 115° ± 17° and radiologic loosening occurred in 8% (2% symptomatic). PROMS showed the following results: HSS 79 ± 18, KSS 78 ± 27, OKS 26 ± 10, EQ-5D index 0.741 ± 0.233 and VAS 70 ± 20. Primary cases revealed better outcomes in HHS (p = .035) and OKS (p = 0.047). KSS, EQ-5D index and VAS did not differ between primary and revision cases (p = 0.070; p = 0.377; p = 0.117). Revision rate was 6.3% with an implant survival of 96.8%.

Conclusions
RHK arthroplasty can be performed with good clinical outcome and low revision rate in revision and complex primary cases. RHK is an option in cases where standard arthroplasty and even implants with a higher degree of constraint have reached their limits.

Level of Evidence
Level III, retrospective cohort study.
The RSNA ImageShare — Enabling Secure, Transparent, and Easy Image Exchange
Authors: Mendelson David S. , Carr Chris , Davis Blanca “Didi” 
Published: August 2022

AbstractIn the early 2000s, the radiology community was awakened to the limitations of electronic media (CDs, DVDs) for exchanging imaging exams. Clinicians frustrated by the time-consuming task of opening discs, while Internet-based exchange of music, photos, and videos were becoming more widespread. The RSNA, which had extensive experience working on interoperability issues in medical imaging, began to look for opportunities to address the issue. In 2007, in the wake of the financial crisis, the National Institute of Biomedical Imaging and Bioengineering (NIBIB) issued an RFP to address Internet-based exchange of medical images. The RFP defined requirements for the network, including that it needed to be patient controlled and standards based. The RSNA was awarded funding for what came to be known as RSNA ImageShare. Over the next 8 years, the RSNA worked in partnership with several vendors and academic institutions to create a network for sharing image-enabled personal health records (PHR). The foundation of interoperability standards used in ImageShare was provided by Integrating the Healthcare Enterprise (IHE), a standards-development organization with which RSNA has had a long association. In 2018 and 2019, the RSNA looked at what had been accomplished and asked if we could take that next step at a national level and promote a solution by which any standards-compliant party could exchange imaging exams through an HIE mechanism.
Two-step success rate criterion strategy: a model- and data-driven partial ambiguity resolution method for medium-long baselines RTK
Authors: Hou Yanqing , Liu Xin , Zhang Haoli , Zhou Dezhong , Guo Jiaju , Li Zishen 
Published: August 2022

AbstractWhen GNSS measurement errors such as ionospheric delays remain large, full ambiguity resolution (FAR) takes an unacceptably long time to fix ambiguities to integers. Partial ambiguity resolution (PAR), under this circumstance, is a possible solution to obtain precise positioning before FAR is achieved. PAR fixes a subset of ambiguities instead of all to improve either the fix rate, success rate or positioning accuracy according to different criteria. This contribution proposes a two-step success rate criterion (TSRC) strategy that first chooses ambiguities to fix using a given success rate threshold and then adds more ambiguities to fix by maximizing the expectation of baseline precision improvement from fixing ambiguities. Then, the TSRC strategy is compared with two other commonly used PAR strategies and the FAR strategy in an experiment with real data forming a medium-long-baseline setup (baselines longer than 15 km and shorter than 50 km). The results show that in medium-long-baseline cases, the TSRC achieves the shortest time to first fix (TTFF), which is 100–200 s shorter than other PAR strategies and 400–800 s shorter than the FAR strategy, excluding cases in which FAR fixes no ambiguities at all. Consequently, the TSRC yields the highest positioning accuracy on average. In addition, the variance–covariance (VC)-matrix of the float ambiguities is found to have a heavy impact on the TSRC strategy in some cases, and amplifying the VC-matrix before the ambiguity fixing process can partly mitigate it.
Disjunct resident population of Melodious Lark Mirafra cheniana discovered in East Africa
Authors: Finch Brian W. , Hatfield R. Stratton , Colombo Silvia , Kennedy Adam S. , te Raa Marije , Irestedt Martin , de Swardt Dawid H. , Grosel Joe , Engelbrecht Derek , Cohen Callan , Olsson Urban , Donald Paul F. , Njoroge Peter , Frahnert Sylke , de Knijf Peter , Alström Per 
Published: August 2022

AbstractWe describe the discovery of a previously unknown population of Melodious Lark Mirafra cheniana from northern Tanzania and southern Kenya, some 2000 km north of what was previously thought to be its northern limit in central Zimbabwe. The identification of this population as M. cheniana is based primarily on analyses of mitochondrial DNA and song. We also clarify relationships within this genus by sequencing material of White-tailed Lark Mirafra albicauda for the first time; although its relationships with other species in the group remain unclear, our analyses clearly show it to be different from M. cheniana in the newly discovered population. The discovery of a population of M. cheniana in East Africa conforms to a known pattern for closely related lark species to have disjunct distributions in southern and eastern Africa.
Perspectival Quantum Realism
Authors: Dieks Dennis 
Published: August 2022

AbstractThe theories of pre-quantum physics are standardly seen as representing physical systems and their properties. Quantum mechanics in its standard form is a more problematic case: here, interpretational problems have led to doubts about the tenability of realist views. Thus, QBists and Quantum Pragmatists maintain that quantum mechanics should not be thought of as representing physical systems, but rather as an agent-centered tool for updating beliefs about such systems. It is part and parcel of such views that different agents may have different beliefs and may assign different quantum states. What results is a collection of agent-centered perspectives rather than a unique representation of the physical world. In this paper we argue that the problems identified by QBism and Quantum Pragmatism do not necessitate abandoning the ideal of representing the physical world. We can avail ourselves of the same puzzle-solving strategies as employed by QBists and pragmatists by adopting a perspectival quantum realism. According to this perspectivalism (close to the relational interpretation of quantum mechanics) objects may possess different, but equally objective properties with respect to different physically defined perspectives. We discuss two options for such a perspectivalism, a local and a nonlocal one, and apply them to Wigner’s friend and EPR scenarios. Finally, we connect quantum perspectivalism to the recently proposed philosophical position of fragmentalism.
The role of methylation profiling in histologically diagnosed neurocytoma: a case series
Authors: Kalawi Adam Z. , Malicki Denise M. , Abdullaev Zied , Pratt Drew W. , Quezado Martha , Aldape Kenneth , Elster Jennifer D. , Paul Megan R. , Khanna Paritosh C. , Levy Michael L. , Crawford John R. 
Published: August 2022

Abstract
Purpose
To highlight the clinical, neuroradiographic, neuropathologic, and molecular features of histologically identified neurocytoma in a pediatric cohort and highlight the evolving use methylation profiling in providing diagnostic clarity in difficult to diagnosis pediatric brain tumors.

Methods
Five consecutive children (ages 9–13, 2 girls 3 boys) were histologically diagnosed with neurocytoma at Rady Children’s Hospital San Diego from 2012 to 2018. Clinical and molecular features were analyzed with regards to treatment course and outcome.

Results
Presenting symptoms included seizures (n = 2), syncope (n = 1), headache (n = 2), visual disturbances (n = 2) and emesis (n = 2). Tumor location included intraventricular (n = 2), intraventricular with parenchymal spread (n = 1), and extraventricular (n = 2). Magnetic resonance imaging demonstrated reduced diffusivity (2/5), signal abnormality on susceptibility-weighted sequences (3/5), and varying degrees of contrast enhancement (4/5). All patients underwent surgical resection alone. Recurrence occurred in four children that were treated with surgery (4/4), adjuvant radiation (2/4), and chemoradiation (1/4). Neuropathologic features included positivity for GFAP (4/5), synaptophysin (4/5), NSE (2/2), NeuN (4/4), and variable Ki-67 (< 1% to 15%). Next generation sequencing (3/5) and microarray (3/5) collectively were abnormal in four of five tumors. Methylation profiling was successfully performed on four of five samples which led to modification of diagnosis in two patients and the others were either unclassifiable or confirmatory with the histologic diagnosis. Mean time to follow up was 77 months (range 44–112 months). Mean progression free survival and overall survival were 24 months (range 6 to 52 months) and 100% respectively.

Conclusion
Neurocytomas are a rare clinical entity that warrants further investigation into molecular and pathologic prognosticating features. Methylation profiling may aid in differentiation of neurocytoma from other difficult to diagnose tumors who share similar histologic features.
Monetary Policy Announcements, Information Shocks, and Exchange Rate Dynamics
Authors: Gründler Daniel , Mayer Eric , Scharler Johann 
Published: August 2022

AbstractWe study nominal exchange rate dynamics in the aftermath of U.S. monetary policy announcements. Using high-frequency interest rate and stock price movements around FOMC announcements, we distinguish between pure monetary policy shocks and information shocks, which are associated with new information contained in the announcements. Contractionary pure policy shocks give rise to a strong, but transitory, appreciation on impact. Information shocks also appreciate the exchange rate, but the effect builds up only slowly over time and is highly persistent. Thus, we conclude that although the short-run effects on the exchange rate are primarily due to pure policy shocks, the medium-run response is driven by information effects.
Eidetic description of consciousness, or consciousness explained in its own right
Authors: Marbach Eduard 
Published: August 2022

AbstractIn the context of «reassessing the relationship between explanation and phenomenology», the paper discusses the question in what ways Husserlian phenomenology as a descriptive science of consciousness has an explanatory potential in consciousness studies. It takes a very limited approach to the wide-ranging themes that may come to mind on this topic. At the center is an exploration of consciousness as an explanandum in its own right, building on Husserl's reflective-eidetic analyses of conscious experiences. It will concentrate on explicating acts of intuitive representification ( anschauliche Vergegenwärtigungen) as intentional modifications of perception, making up higher, radical novel levels of intentionality. Acts of remembering, imagining, depicting something, as well as iterations and combinations of such acts, will serve as examples. A formal notation will be used with the intention to make the reflection-based theoretical language of phenomenology more precise and easier to survey.
Democracy and the quality of economic institutions: theory and evidence
Authors: Krieger Tommy 
Published: August 2022

AbstractWe present a simple model, illustrating how democracy may improve the quality of the economic institutions. The model further suggests that institutional quality varies more across autocracies than across democracy and that the positive effect of democracies on economic institutional quality increases in people’s human capital. Using a panel data set that covers 150 countries and the period from 1920 to 2019, and different measures of economic institutional quality, we show results from fixed effect and instrumental variable regressions that are in line with the predictions of our model.
Quality-adjusted life years among people who inject drugs in a needle syringe program in Sweden
Authors: Kåberg Martin , Larsson Sofie , Bergström Jakob , Hammarberg Anders 
Published: August 2022

Abstract
Purpose
Needle syringe programs (NSP) significantly reduce risk behavior and HIV and hepatitis transmission in people who inject drugs (PWID). However, PWID are underrepresented in studies on health-related quality of life (HRQoL), representing a barrier to evaluate effects of public health and preventive measures related to injecting drug use. In this study, we investigate how well the two questionnaires EQ-5D-3L and SF-6D measure health in PWID. We also estimate HRQoL in the PWID population.

Method
Data on demographics, injection drug use, HIV, hepatitis status, and self-reported HRQoL were collected from 550 PWID enrolled in the Stockholm NSP at enrollment and at 6-, 12-, and 24-month follow-up. Self-rated HRQoL was measured as QALY, using EQ-5D-3L and the SF-6D. Item response theory (IRT) was used to evaluate which of the two instruments that measure health most accurately in this population. Regression analysis was used to estimate population-specific QALYs.

Results
The IRT analysis showed that SF-6D was better suited to measure health in PWID. More specifically, SF-6D to a larger extent discriminated between persons regardless of their health status, while EQ-5D was more suitable to detect persons with poorer health. Self-rated HRQoL showed that average QALY was lower among PWID compared to the general Swedish population. However, a general increase in self-reported health was noted over time among participants.

Conclusion
This study increase knowledge of what instruments are most suitable to measure health among PWID. This is of great importance when evaluating effects of public health and preventive measures in the PWID population.
How to measure parenting styles?
Authors: Rauh Christopher , Renée Laëtitia 
Published: August 2022

AbstractIn this paper, we measure parenting styles through unsupervised machine learning in a panel following children from age 5 to 29 months. The topic model, which is a statistical model originally developed to discover the latent semantic structures in text, classifies parents into two parenting styles: “warm” and “cold”. Parents of the warm type tend to respond to children’s expressions in a supportive manner, while parents of the cold type are less likely to engage with their children in an encouraging manner. Warm parenting is more likely amongst educated and older mothers. Although styles reveal some persistence, the share of parents with a warm style decreases with the age of the child, in particular for boys. Children of warm parents achieve higher cognitive and non-cognitive scores at later ages. We find that the topic model estimated on different sample splits, such as by education or child age, reveal additional information while maintaining robust overall patterns.
The Importance of Different Forms of Social Capital for Happiness in Europe: A Multilevel Structural Equation Model (GSEM)
Authors: Gómez-Balcácer Lucía , Somarriba Arechavala Noelia , Gómez-Costilla Patricia 
Published: August 2022

AbstractThis paper investigates the effects of different dimensions of social capital ​on happiness of Europeans. Unlike other studies, a categorical principal component analysis (CATPCA) is applied to obtain the dimensions of social capital. The data used come from the ninth wave of the European Social Survey (ESS), year 2018. Happiness is modelled using a multilevel structural equations model (GSEM) by country to study the role of social capital in Europeans' happiness, when controlling for the effect of factors such as gender, unemployment, age, low income, higher education, and living with a partner. Social capital is measured as a multidimensional concept composed of institutional trust, social trust, social ties and voluntary association, civility and sense of belonging, and religiosity. Among the results, we found that the five dimensions that build social capital have a positive impact on happiness. In addition to the positive effects of social capital, the control variables have the expected impact. In a context marked by growing individualism and social isolation, the results of this work can guide policy makers in using the dimensions of social capital to increase the subjective well-being of the population.
An In-Plane Bending Test to Characterize Edge Ductility in High-Strength Steels
Authors: Khalilabad M. Masoumi , Perdahcıoğlu E. S. , Atzema E. H. , van den Boogaard A. H. 
Published: August 2022

AbstractA novel in-plane bending test was used to study edge ductility in DP800 as a common advanced high-strength steel in the car industry. The test utilized the digital image correlation technique to measure the local and average fracture strain values along the edge of the specimen. In contrast to the widely used hole expansion capacity test, the impact of punch friction, contact stress, and out-of-plane strain on edge ductility is eliminated by removing the punch. Also, the strain gradient inherent to the beam bending provides a controlled crack propagation path, making crack tracking easier than the sheared edge tensile test. The proposed bending test was utilized to investigate the influence of material orientation, cutting parameters, and global strain gradient on edge fracture strain. A correlation was observed between edge ductility, material orientation, and cutting tool sharpness, while the average fracture strain was independent of the strain gradient. The outcome shows that the in-plane bending test is reliable for determining edge ductility in any desired material orientation.
Metadata analysis to explore hub of the hub-genes highlighting their functions, pathways and regulators for cervical cancer diagnosis and therapies
Authors: Reza Md. Selim , Hossen Md. Alim , Harun-Or-Roshid Md. , Siddika Mst. Ayesha , Kabir Md. Hadiul , Mollah Md. Nurul Haque 
Published: August 2022

AbstractCervical cancer (CC) is considered as the fourth most common women cancer globally.that shows malignant features of local infiltration and invasion into adjacent organs and tissues. There are several individual studies in the literature that explored CC-causing hub-genes (HubGs), however, we observed that their results are not so consistent. Therefore, the main objective of this study was to explore hub of the HubGs (hHubGs) that might be more representative CC-causing HubGs compare to the single study based HubGs. We reviewed 52 published articles and found 255 HubGs/studied-genes in total. Among them, we selected 10 HubGs (CDK1, CDK2, CHEK1, MKI67, TOP2A, BRCA1, PLK1, CCNA2, CCNB1, TYMS) as the hHubGs by the protein–protein interaction (PPI) network analysis. Then, we validated their differential expression patterns between CC and control samples through the GPEA database. The enrichment analysis of HubGs revealed some crucial CC-causing biological processes (BPs), molecular functions (MFs) and cellular components (CCs) by involving hHubGs. The gene regulatory network (GRN) analysis identified four TFs proteins and three miRNAs as the key transcriptional and post-transcriptional regulators of hHubGs. Then, we identified hHubGs-guided top-ranked FDA-approved 10 candidate drugs and validated them against the state-of-the-arts independent receptors by molecular docking analysis. Finally, we investigated the binding stability of the top-ranked three candidate drugs (Docetaxel, Temsirolimus, Paclitaxel) by using 100 ns MD-based MM-PBSA simulations and observed their stable performance. Therefore the finding of this study might be the useful resources for CC diagnosis and therapies.
Impact of ATC speed instructions on fuel consumption and noise exposure: an assessment of real operations in Zurich
Authors: Abdelmoula Fethi , Roeser Mathias S. , Kühne Christoph G. , Gerber Martin , Wunderli Jean-Marc 
Published: August 2022

AbstractApproach operations at busy airports are louder and less fuel efficient than they technically could be. Carrying out a safe approach under fluctuating wind and weather conditions while following individual air traffic control (ATC) instructions imposes a significant workload on the flight crew, especially with the limited systems support and information availability on the flight deck today. The SESAR exploratory research project DYNCAT (Dynamic Configuration Adjustment in the TMA) aims to highlight the impact of current approach operations on the environment based on all relevant data sources (on-board operational data, ATC commands, noise measurement data, surrounding traffic and weather information) allowed to evaluate individual approach operations in their full context, exemplarily for the Airbus A320 at Zurich airport. The evaluations performed are a unique opportunity to analyse the impact of ATC instructions on fuel consumption and noise exposure during real operations. The results showed that speed instructions, especially when given early during the transition phase, lead to high fuel consumption, due to the long-time flight in low speed levels correlated to earlier usage of Flaps configurations. A mean difference of almost 50 kg in fuel burned is observed when comparing the flights with speed restrictions to those without. On the other hand, speed restrictions provide a well-defined airspeed guidance for the pilots during transition and final approach, which leads to lower usage of speed brakes and also to lower speed levels for the landing gear extension. The less speed restrictions were given to the pilots by ATC, the higher was the usage of speed brakes during the final approach, and also the landing gear deployment was performed at higher speed levels, which ceteris paribus contributes significantly to the noise exposure and noise footprint. Based on these evaluations, requirements for a novel flight management system (FMS) function, which is set to be developed in the next steps of the project, were derived to support pilots and controllers through extended information exchange, thus increasing predictability of the lateral and vertical flight profiles for both sides. A central component is a novel airborne energy management assistance system including a configuration management functionality, to be implemented through an extension of the FMS capabilities.