bluuebunny/crossref_metadata_2025_split huggingface dataset:
ADVANTAGES AND DISADVANTAGES OF STUDYING ABROAD FOR RUSSIAN STUDENTS
Authors: Елинсон Мария Альбертовна , Субхангулов Аскар Зуфарович 
Published: July 2022

Статья посвящена исследованию обучения за рубежом для российских студентов. Приведены главные преимущества и недостатки обучения заграницей.
The article is devoted to the study of education abroad for Russian students. The main advantages and disadvantages of studying abroad are considered.
ABOUT THE MECHANISMS OF THE PROTECTIVE INFLUENCE OF CARNOSINE IN NON-ALCOHOLIC FATTY LIVER DISEASE
Authors: Трушина Элеонора Николаевна 
Published: July 2022

В статье приводится краткий обзор литературы о механизмах протективного влияния карнозина при неалкогольной жировой болезни печени.
The article provides a brief review of the literature on the mechanisms of the protective effect of carnosine in non-alcoholic fatty liver disease.
INFRARED SENSORS AND THEIR APPLICATION
Authors: Тимербаев Артур Русланович , Буслова Надежда Сергеевна 
Published: July 2022

В статье рассматривается понятия первичных преобразователей и инфракрасных датчиков, приводится их классификация, описывается принцип работы, а также область применения.
The article discusses the concepts of primary converters and infrared sensors, provides their classification, describes the principle of operation, as well as the scope of application.
HUbungan Tingkat Kecemasan Terhadap Kinerja Dosen dan Karyawan Universitas Muhammadiyah Bengkulu Di Masa New Normal Covid 19
Authors: FATSIWI NUNIK ANDARI  
Published: July 2022

Corona virus desease (Covid-19) yang pertama kali ditemukan di Wuhan, Cina telah dinyatakan sebagai pandemi. WHO mencatat sebanyak 213 negara terpapar kasus Covid-19. Jumlah penambahan kasus baru terkonfirmasi positif dan jumlah kematian dalam satu hari terus mengalami peningkatan, termasuk di Provinsi Bengkulu. Tingginya angka kejadian ini menimbulkan kecemasan bagi setiap orang, termasuk dosen dan karyawan Universitas Muhammadiyah Bengkulu. Penelitian ini bertujuan untuk mengetahui hubungan tingkat kecemasan dengan kinerja dosen dan karyawan Universitas Muhammadiyah Bengkulu yang bekerja di masa new normal Covid-19. Penelitian ini menggunakan pendekatan cross sectional dengan jumlah sampel sebanyak 90 orang. Pengumpulan data dilakukan dengan menggunakan kuesioner Zung Self Anxiety Rating-Scale (ZSAR-S) dan kuesioner Individual Work Performance Questionnaire (IWPQ). Hasil penelitian dengan analisis Spearman Rank test menunjukkan bahwa tidak ada hubungan yang signifikan antara tingkat kecemasan dengan kinerja dosen dan karyawan Universitas Muhammadiyah Bengkulu saat bekerja di masa new normal Covid-19 dengan p-value = 0.855. Kesimpulan dari penelitian adalah tidak ada hubungan antara tingkat kecemasan dengan kinerja dosen dan karyawan Universitas Muhammadiyah Bengkulu di masa new normal Covid-19.
Kata Kunci : Dosen, Karyawan, Kecemasan, Kinerja, New normal
Recipientes islámicos de vidrio dorado encapsulado: evidencias en al-Andalus
Authors: Velo-Gala Almudena , Govantes-Edwards David , Duckworth Chloë N. 
Published: July 2022

Dentro del repertorio de la vajilla de vidrio andalusí son escasos los testimonios que se conocen de vidrios dorados. Por este motivo, se ha procedido al análisis morfológico y comparativo de un conjunto de fragmentos, la gran mayoría inéditos, hallados en contextos arqueológicos bien documentados, concretamente de Madinat Ilbira (Granada), el arrabal noroccidental de Qurtuba (Córdoba) y el Conjunto Arqueológico de San Esteban (Murcia), con el objetivo de determinar su importancia y aportar datos sobre algunas cuestiones generales sobre su contexto y su datación. Los resultados han permitido confirmar la existencia de las dos tipologías hasta el momento conocidas, cuencos/vasos y botellas, todos ellos elaborados mediante la técnica de oro encapsulado entre dos capas de vidrio. La similitud de los diseños decorativos indicaría un origen común para todas las piezas, posiblemente, en la zona del Mediterráneo oriental. Los contextos señalan, además, un patrón de consumo en los ambientes domésticos andalusíes que abarcan una cronología entre los siglos IX-XII d. C., con una destacada presencia en la capital del califato.
Predictors of Catching COVID-19 Infection during Pandemic Stage in Patients with Multiple Sclerosis (MS)
Authors: Ghajarzadeh Mahsa , Mirmosayyeb Omid , Molazadeh Negar , Sahraian Mohammad Ali , Bonavita Simona , Shaygannejad Vahid 
Published: July 2022

Background:
Patients with multiple sclerosis (MS) are considered at higher risk of COVID-19 infection due to treatment with immune modulators and immune-suppressive agents. The exact risk factors are not clear. So, we aimed to conduct a study to determine the predictors of catching COVID-19 infection during the pandemic stage in patients with multiple sclerosis (MS).

Methods:
We conducted a multicenter screening study and developed an online questionnaire to collect patients’ self-reported demographic features along with MS-related and COVID-19–related information. The online questionnaire link was released by the Iran Multiple Sclerosis Society (IMSS) social media channel, accessible for 4160 MS patients totally and also was sent by WhatsApp for nonmember cases.

Results:
Totally, 1448 MS patients participated in our study. Twenty-five (1.7%) patients were diagnosed with COVID-19, from which 4 were hospitalized, 4 were treated with medical therapy, and 17 patients had home-quarantine. The patients with COVID-19 diagnosis were more frequently treated with rituximab (28% vs 24%, P = 0.001) than others, and cardiovascular comorbidity was more frequent in this group (8% vs 1.6%, P = 0.01). Regression analysis showed that cardiovascular disease was a significant positive predictor of COVID-19 infection (OR = 5.2, 95% CI: 1.1–23.7).

Conclusions:
Patients with MS who have cardiovascular disease should be more monitored for COVID-19 infection as they are at higher risk of infection.
Primary osteosarcoma of breast - A clinical camouflage: Case report
Authors: Bandegudda Santhoshkumar , N Raju KVV , Kodandapani Suseela , Rao Jayakartik 
Published: July 2022

ABSTRACT
Primary sarcoma of the breast is a rare clinical entity with an incidence of less than 1% among cases of breast cancer. Primary osteosarcoma of the breast is a very rare disease that shares clinical features similar to metaplastic breast carcinoma. A 57-year-old female Dravidian patient presented with a breast lump. A needle biopsy was suggestive of carcinoma. However, the mammogram was suggestive of dense calcification lesion, which is unusual in carcinoma. She underwent breast conservation surgery with sentinel lymph node biopsy; final histopathology was suggestive of osteosarcoma of the breast. After a follow-up of 18 months, the patient is healthy and disease-free. Primary breast osteosarcoma has to be considered as one of the differential diagnoses to metaplastic carcinoma and warrants a different treatment approach. Whenever there is discordance in clinical features, imaging, and histology, thorough evaluation with the mammogram, immunohistochemistry, and PET scan helps to resolve the issue.
Antiproliferative effect of Potentilla fulgens on glioblastoma cancer cells through downregulation of Akt/mTOR signaling pathway
Authors: Kandemir Sevgi Irtegun , Ipek Polat 
Published: July 2022

ABSTRACT

Background:
Glioblastoma multiforme (GBM) is the most aggressive brain tumor that is common among adults. This aggression is due to increased invasion, migration, proliferation, angiogenesis, and decreased apoptosis. Plant-based compounds have a high potential to be used as an anticancer agent due to their various mechanisms and less undesirable side effects. Potentilla fulgens is a medicinal plant, and methanolic root extract of P. fulgens (PRE) has anti-inflammatory and anticancer properties.

Objective:
In this study, we aimed to investigate antiproliferative effect of PRE on U118 and T98G glioblastoma cancer cells and to reveal which molecular signaling pathways regulate this mechanism of action.

Materials and Methods:
The effect of PRE on cell viability of GBM cells was investigated by MTT assay. Involvement of PRE with cell growth and survival signaling pathways, phosphatidylinositol 3-kinase (PI3K)/Akt/mTOR and c-Src/signal transducer and activator of transcription 3 (STAT3), was examined using Western Blot.

Results:
PRE reduced cell viability of GBM and human dermal fibroblast (HDF) cells in a dose-and time-independent manner. PI3K expression/phosphorylation level remained unchanged in both GBM and HDF cells after PRE treatment, but Akt/mTOR signaling pathway was downregulated in PRE-treated cells. PRE treatment did not affect c-Src expression/phosphorylation level in GBM cells; however, expression of c-Src was suppressed in HDF cells. Similar results were observed for STAT3 expression and phosphorylation status.

Conclusion:
PRE has the ability to suppress cell viability in GBM cells, by targeting the Akt/mTOR signaling pathway.
Association of Cognitive Function, Depression, and Quality of Sleep with Statins among Oldest-Old Individuals
Authors: Regalla Sai Sruthi , Anaika Gunampalli , Reddy Bana Manishaa , Sharma Pawan Kumar , Ganguly Enakshi 
Published: July 2022

Background:
Oldest-old population is rapidly increasing in all countries, with many prescribed statin therapy. Statins are associated with multiple cardiovascular benefits at various ages. The benefits of statins above the age of 75 are being questioned. The objective of this study was to measure statins use among the oldest-old population, aged 80 years and above, and to study the effect of statins on cognitive function, depression, and quality of sleep.

Materials and Methods:
This cross-sectional study randomly enrolled 200 community-dwelling individuals aged >80 years. Data were collected upon home visits on sociodemographic, cognitive functions, depression, sleep, chronic diseases, functional limitations, and disabilities. Cognitive function (Mini Mental State Examination), depression (Geriatric Depression Scale), and quality of sleep (Pittsburgh Sleep Quality Index) among individuals using statins versus not using statins were compared. Chi-square test and t-test were done; odds ratios (ORs) with 95% confidence interval (95% CI) were reported. Logistic regression was done to calculate adjusted OR with age, antidepressants, sedatives, antihistaminics, and sleep medicines. P < 0.05 was considered statistically significant.

Results:
Overall prevalence of statin use in our study population was 12%; 11.3% in women and 13.2% in men. Cognitive functions, depression, and quality of sleep improved among those using statins (P < 0.05): cognitive impairment – OR: 0.38; 95% CI: 0.16–0.91; depression – OR: 0.41; 95% CI: 0.17–1.02, and poor sleep quality – OR: 0.39; 95% CI: 0.16–0.96. On stratification by gender, men showed a significant association of improved cognitive function and quality of sleep with the use of statins, whereas women did not show any significant associations with cognitive function and quality of sleep but showed almost significant association with improvement in depression.

Conclusions:
The prevalence of the use of statins was low in our population. Statins had positive effects on cognitive functions, quality of sleep, and depression over 80 years of age in our population, although gender difference exists.
Safety and Efficacy of Ayush Rasayana A and B in Improving Functionality of the Elderly – A Single-Arm Multicenter Study
Authors: Dey Aparajit B. , Gambhir Inderjeet Singh , Hazra Jayram , Sharma Sakshi , Mundada Pallavi S. , Mata Sunita , Chakrawarty Avinash , Singh Om P. , Mitra Achintya , Rana Rakesh K. , Singhal Richa , Vedi S. K. , Sharma Ramavtar , Kumar Adarsh , Gupta Bharti , Padhi Madan M. , Srikanth Narayanam , Dhiman Kartar Singh 
Published: July 2022

Background:
As per Ayurvedic classics, Rasāyana is a term used for unique therapeutic measures intended to improve cognition, memory, physical strength and delay the degenerative processes. Ayush Rasayana A & B are developed from extracts of herbs pertaining rasayana property.

Aims & Objectives:
To assess the safety and effectiveness of 'Ayush Rasayana A and B' in improving physical endurance, quality of life and cognition of elderly.

Materials and Methods:
This is an open label, single arm, multi-centre study among 256 apparently healthy elderly between 60-75 years. Ayush Rasayan A was given for 6 days and Ayush Rayana B for 180 days. The effect of the trial drug was seen on functional capacity, quality of life and cognitive function and, safety of the intervention was assessed through haematological and biochemical tests, clinical examination and incidence of adverse events.

Results:
Significant improvement in 6 minute walk test and HMSE score was observed at 187th as compared to baseline (p<0.0001). Quality of life of the participants especially in domains of physical health, social relationship and environment also improved at the end of intervention period (p<0.0001). The haematological and bio-chemical parameters showed no significant changes as compared to baseline and no adverse events were observed during the study.

Conclusion:
Ayush Rasayana A and Ayush Rasayana B, both were well tolerated by all the participants. This ayurvedic intervention can be safely given to apparently healthy elderly to improve their functionality, quality of life and cognition. However, a randomized controlled trial is warranted to substantiate the efficacy of this drug.

Trial Registration:
CTRI/2015/04/005679 dated 8th April 2015.
Does outer retinal layer thickness correlate with the central visual field indices in early dry age-related macular degeneration?
Authors: Acharya Sarmila , Kharel Sitaula R , Karki Pratap , Mishra Sanjeeb Kumar , Dahal Hira Nath , Poudel Amit 
Published: July 2022

PURPOSE:
Age-related macular degeneration (ARMD) is the leading cause of irreversible blindness worldwide and Nepal is one among them. We aimed to determine the relationship between outer retinal layer thickness parameters with central visual field indices in early dry ARMD cases among Nepalese population.

MATERIALS AND METHODS:
The subjects for this descriptive, cross-sectional study comprised 40 patients with early dry ARMD from the ophthalmology department of a tertiary level hospital of Nepal. The retinal layer thickness was measured with spectral-domain optical coherence tomography (SD-OCT), and the visual field indices were assessed using the 10-2 protocol of Humphrey visual field analyzer (HFA). Thus, the retinal layer structures correlated with visual field indices among our population.

RESULTS:
Among our early dry ARMD population, the foveal threshold (FT) was found to be significantly correlated with retinal pigment epithelium (RPE) elevation (P < 0.01, r = −0.541), outer segment (OS) length (P = 0.02, r = 0.465), and inner segment ellipsoid (ISe) band disruption (P = 0.01, r = −0.499), but not with presence of hyperreflective foci (P = 0.464), RPE thickness (P = 0.612), and central macular thickness (P = 0.214). However, no significant correlation between mean deviation and pattern standard deviation of visual field with retinal layer thickness parameters was identified.

CONCLUSION:
In early dry ARMD, a reduced FT is significantly correlated with the integrity of the ISe band, thinning of OS length, and drusen-associated RPE elevation. The results highlight the utility of both SD-OCT retinal layer measurement and central visual field testing by HFA in ARMD to monitor the progression of the disease.
Emboli Udara Vena saat Seksio Sesarea
Authors: Yulianti Bisri Dewi , Bisri Tatang 
Published: July 2022

Seksio sesarea telah dikaitkan dengan emboli udara vena (venous air embolism/VAE). Sinus uterus rentan sebagai pintu masuk udara, terutama dengan adanya plasenta previa. Insiden VAE selama seksio sesarea telah dilaporkan antara 9,5% dan 65%, dan ini dapat terjadi selama anestesi epidural, anestesi spinal, dan anestesi umum. Emboli udara dalam sirkulasi paru dapat menyebabkan ketidakcocokan ventilasi/perfusi dan dapat menurunkan saturasi oksigen. Nyeri dada dan dyspnea dapat dikaitkan dengan VAE, dan juga telah diamati adanya perubahan ECG. Sebagian besar perubahan terjadi pada sayatan uterus dan persalinan serta pada saat eksteriorisasi uterus. Oleh karena itu, saturasi oksigen, tekanan darah, dan denyut nadi harus dipantau secara ketat selama persalinan dan segera pascapersalinan
MALE PARTICIPATION IN ANTENATAL CARE AND ITS EFFECT ON PREGNANCY
Authors: Omolola ADERIBIGBE , OHAERI Beatrice , Iyanuoluwa OJO , BABARIMISA BABARIMISA , ADEBAYO Mercy 
Published: July 2022

Purpose: Male participation in antenatal care (ANC) is important and contributes to better maternal and neonatal birth outcomes. Deaths among mothers remain a serious burden in the developing countries, including Nigeria. Lack of male involvement in pregnancy related care is one of the contributing factors. The purpose of this study is to assess the level of male participation in ANC. In most countries in the world, promotion of maternal and child health is perceived as women’s role and men do not feel that they are responsible and see no reason to accompany their partners to Antenatal Care (ANC) clinics.
Methodology: Cross sectional descriptive survey was used in the study.
Findings: It was discovered that male partners do not fully participate in antenatal care due to many factors like low level of education, fear of being tested for HIV, culture and so on. Male partners/husbands are key support persons for many childbearing women and their involvement in pregnancy, childbirth and the postpartum/postnatal period has beneficial effects on a wide range of outcomes related to maternal and child health and family wellbeing. Male involvement in antenatal care (ANC) is among interventions to improve maternal health. Globally male involvement in ANC is low and varies in low-income and middle-income countries including Nigeria where most maternal deaths occur. In Sub-Sahara, men are chief decision makers and highly influence maternal health.
Unique Contribution to Theory Practice and Policy: It is therefore recommended that male should participate in ANC in order to encourage the wife in the course of pregnancy and promote psychological support.
Analisis Tingkat Kesehatan PT.Bank Negara Indonesia Tbk. Melalui Pendekatan Earnings dan Capital Periode 2014-2018
Authors: Pratama Harie , Halin Hamid , Purnamasari Endah Dewi 
Published: July 2022

This study aims as to analyze the bank financial health rates of PT Bank Negara Indonesia, Tbk. for the period of 2014 to 2018. Data were collected through documentation and analyzed employing the earnings and capital approach using the indicators of return on asset (ROA), net interest margin (NIM), and cash adequacy ratio (CAR). The results unveil that during 2014 to 2018 respectively: (1) the earnings aspects of PT Bank Negara Indonesia, Tbk. were rated highly healthy with an average ROA value of 3.37 percent, 2.48 percent, 2.57 percent, 2.62 percent, 2.58 percent and NIM of 4.79 percent, 4.77 percent, 4.28 percent, 3.43 percent, 3.20 percent; (2) the capital aspects were rated highly healthy with an average CAR value of 16.27 percent, 17.90 percent, 18.78 percent, 18.42 percent, and 18.03 percent; (3) overall earnings and capital aspects at PT Bank Negara Indonesia, Tbk. from 2014 to 2018 were in the composite rank 1 (PK 1) which was highly healthy
Digital Activism in the COVID-19 era
Authors: Jacinto Olga Anaid Diaz , Lirios Cruz García 
Published: July 2022

The exploration of the dimensions of digital activism was the objective of this work. A non-experimental study was carried out with a non-probabilistic selection of 150 students, considering their affiliation with student organizations. A four-dimensional structure was established; technological habitus, computational self-efficacy, diffusion of innovations and Internet mobilization that explained 48% of the total variance, although the design limited the results to the research scenario, suggesting the extension of the study and the inclusion of variables such as training, socialization and intention to use the devices and networks
NUTRITIONAL STATUS SCREENING AND NUTRITION FULFILLMENT EDUCATION IN THE ADOLESCENT FOOTBALL CLUB IN KUBUTAMBAHAN VILLAGE
Authors: Purnamayanti Ni Kadek Diah 
Published: July 2022

Background: Adolescent boys are an age group that needs special attention regarding the fulfillment of nutrition to support activity and growth. The sport activity that is often the choice of teenage boys is soccer. This type of sport requires excellent energy and is classified as a strenuous activity
Purpose: This community service activity aims to carry out early detection of the nutritional status of teenage boys who are members of soccer sports clubs. This activity also provides education to athletes and coaches in Kubutambahan Village.
Methods: This activity was carried out by conducting a physical examination related to anthropometry accompanied by counseling related to the nutrition of soccer athletes. Educational content related to nutrition before the competition, before the competition and after the competition.
Results: All athletes of the U21 soccer club in Kubutambahan Village are at the age of 11-16 years. The total number of youth involved in this activity is 21 people. Most (85.71%) had normal nutritional status. While 9.5% are under nutrition and 4.79% are obese.
Conclusion: Early detection of nutritional status in adolescents who are members of soccer clubs is important to do. Efforts to fulfill long-term nutrition need to involve parents and sponsors in order to realize a balanced nutritional composition.