bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inferior fronto‐occipital fascicle displacement in temporoinsular gliomas using diffusion tensor imaging
Authors: Camins Àngels , Naval‐Baudin Pablo , Majós Carles , Sierpowska Joanna , Sanmillan Jose L , Cos Mónica , Rodriguez‐Fornells Antoni , Gabarrós Andreu 
Published: March 2022

AbstractBackground and PurposeBrain tumors can result in displacement or destruction of important white matter tracts such as the inferior fronto‐occipital fascicle (IFOF). Diffusion tensor imaging (DTI) can assess the extent of this effect and potentially provide neurosurgeons with an accurate map to guide tumor resection; analyze IFOF displacement patterns in temporoinsular gliomas based on tumor grading and topography in the temporal lobe; and assess whether these patterns follow a predictable pattern, to assist in maximal tumor resection while preserving IFOF function.MethodsThirty‐four patients with temporal gliomas and available presurgical MRI were recruited. Twenty‐two had insula infiltration. DTI deterministic region of interest (ROI)‐based tractography was performed using commercial software. Tumor topographic imaging characteristics analyzed were as follows: location in the temporal lobe and extent of extratemporal involvement. Qualitative tractographic data obtained from directional DTI color maps included type of involvement (displaced/edematous‐infiltrated/destroyed) and displacement direction. Quantitative tractographic data of ipsi‐ and contralateral IFOF included whole tract volume, fractional anisotropy, and fractional anisotropy of a 2‐dimensional coronal ROI on the tract at the point of maximum tumor involvement.ResultsThe most common tract involvement pattern was edematous/infiltrative displacement. Displacement patterns depended on main tumor location in the temporal lobe and presence of insular involvement. All tumors showed superior displacement pattern. In lateral tumors, displacement tendency was medial. In medial tumors, displacement tendency was lateral. When we add insular involvement, the tendency was more medial displacement. A qualitative and quantitative assessment supported these results.ConclusionsIFOF displacement patterns are reproducible and suitable for temporoinsular gliomas presurgical planning.
Oxacillinases and antimicrobial susceptibility of Ralstonia pickettii from pharmaceutical water systems in Croatia
Authors: Batarilo I. , Maravic-Vlahovicek G. , Bedenic B. , Kazazic S. , Bingulac-Popovic J. , Slade-Vitkovic M. , Katić S. , Jukic I. 
Published: March 2022

Abstract
This study evaluated antibiotic susceptibility and presence of blaOXA22 and blaOXA60 genes in 81 isolates of Ralstonia pickettii obtained from different purified and ultra-pure water systems in two different geographical areas of Croatia. E-test and disc diffusion test were performed to determine antibiotic susceptibility. Polymerase chain reaction was applied to detect genes encoding OXA-22 and OXA-60 oxacillinases previously identified in R. pickettii. The isolates were genotyped by pulsed-field gel electrophoresis. The results revealed variable susceptibility/resistance profiles. Our isolates exhibited high susceptibility rates to ceftriaxone, cefotaxime, piperacillin-tazobactam, ciprofloxacin, imipenem, cefepime and in lesser extent to ceftazidime. High rates of susceptibility were also observed for sulphamethoxazole-trimethoprim and piperacillin. High resistance rates were noticed for ticarcillin-clavulanate, aztreonam and meropenem, as well as for all aminoglycosides tested. Modified Hodge test was positive in 51·9% strains, indicating production of carbapenemases. blaOXA22 and blaOXA60 genes were detected in 37·0 and 80·3% strains, respectively. Pulsed-field gel electrophoresis identified three major clusters containing subclusters. R. pickettii should be taken seriously as a possible cause of nosocomial infections to ensure adequate therapy, to prevent the development of resistant strains and to try to reduce the possibility of R. pickettii surviving in clean and ultra clean water systems.
The impact of technology use on adolescents' leisure reading preferences
Authors: Loh Chin Ee , Sun Baoqi 
Published: March 2022

AbstractThere is worldwide concern about the decline in children and adolescent enjoyment of reading as documented by international and national surveys, with smartphones and other technologies often blamed for the decline. Yet, with recent rapid improvements in technologies for reading, the accelerated adoption of devices for learning during the pandemic and increased access to e‐books through the public library system in Singapore, the relationship between adolescent technology use and reading may be more complex than is typically painted in popular press. This mixed‐methods study seeks to make current an understanding of adolescent reading in relation to technology by exploring adolescents' preferred reading devices, their use of technology for reading and their use of public e‐resources for reading. In this study, adolescents preferred using their smartphones over print forms for reading and preferred to read social media online. E‐books accessed freely through the public library were under‐utilised, and adolescents reported lack of knowledge or experience about how to look for reading resources online. Findings suggest an intentional and nuanced approach is needed to create an ecosystem of opportunities for adolescents to have meaningful reading experiences in print and digitally.
Seasonal variation and intra urban heterogeneity of the entomological risk of transmission of dengue and yellow fever in Abidjan, Côte d'Ivoire
Authors: Guindo‐Coulibaly Négnorogo , Kpan Mintokapieu Didier Stephane , Adja Akré Maurice , Kouadio Affoué Mireille Nadia , Assouho Konan Fabrice , Zoh Dounin Danielle , Azongnibo Konan Rodolphe Mardoché , Remoue Franck , Fournet Florence 
Published: March 2022

AbstractDengue and yellow fever are prevalent in Côte d'Ivoire and Aedes (Stegomyia) aegypti (Linnaeus), (Diptera: Culicidae), is known as the main vector. We aimed to assess seasonal variation and spatial heterogeneity in the transmission of both arbovirus diseases in Abidjan. Entomological surveys targeting larvae of A. aegypti, were carried out between November 2015 and August 2016 covering the four climatic seasons including a cohort of 100 houses randomly selected in three neighbourhoods. A. aegypti was the predominant species (96.6%) of mosquitoes resulting from the rearing of harvested larvae, and the only vector of dengue and yellow fever recorded during the study period. The highest proportion of water storage containers (45.5%) which represented the major breeding sites infested by the larvae of A. aegypti, was observed in Anoumabo. The house indices >5% and/or Breteau indices >20 recorded in each neighbourhood, during the different climatic seasons, indicated that there was, a high and permanent, heterogeneity in the transmission risk of dengue and yellow fever between the three neighbourhoods. In terms of transmission risk, Anoumabo was the neighbourhood with the highest risk compared to the two others, then, particular attention should be paid to this site in terms of surveillance by vector control programme in Abidjan.
Disentangling the effects of trait and state worry on error‐related brain activity: Results from a randomized controlled trial using worry manipulations
Authors: Härpfer Kai , Carsten Hannes Per , Löwisch Kim , Westermann Nele , Riesel Anja 
Published: March 2022

AbstractEnhanced amplitudes of the error‐related negativity (ERN) have been suggested to be a transdiagnostic neural risk marker for internalizing psychopathology. Previous studies propose worry to be an underlying mechanism driving the association between enhanced ERN and anxiety. The present preregistered study focused on disentangling possible effects of trait and state worry on the ERN by utilizing a cross sectional observational and a longitudinal randomized controlled experimental design. To this end, we examined the ERN of n = 90 students during a flanker task (T0), which were then randomly assigned to one of three groups (worry induction, worry reduction, passive control group). Following the intervention, participants performed another flanker task (T1) to determine potential alterations of their ERN. Manipulation checks revealed that compared to the control group, state worry increased in the induction but also in the reduction group. ERN amplitudes did not vary as a function of state worry. An association of trait worry with larger ERN amplitudes was only observed in females. Furthermore, we found larger ERN amplitudes in participants with a current or lifetime diagnosis of internalizing disorders. In summary, our findings suggest that the ERN seems to be insensitive to variations in state worry, but that an elevated ERN is associated with the trait‐like tendency to worry and internalizing psychopathology, which is consistent with the notion that the ERN likely represents a trait‐like neural risk associated with anxiety.
Hemodiafiltration in developing countries
Authors: Kusirisin Prit , Srisawat Nattachai 
Published: March 2022

AbstractHemodiafiltration (HDF) is a promising kidney replacement therapy modality for patients with end‐stage kidney disease. The principle of uremic toxin clearance by combining convection and diffusion can lead to greater benefits compared to conventional hemodialysis. Evidence is building that supports the advantages of HDF with short‐term outcomes such as greater intradialytic hemodynamic stability, improved nutritional status, attenuation of anemia, and reduction of inflammatory cytokines which produce improved key long‐term impacts including survival and cardiovascular outcomes. Very little is known about the prevalence of HDF treatments in developing countries due to a shortage of national kidney registries. HDF experience is limited in many countries due to the cost of dialysis treatments, availability of online HDF machines, and reimbursement policies. These obstacles have led to nephrologists developing innovations, for example, convective control HDF (CC‐HDF), simple mid‐dilution, and simple mixed‐dilution methods, which may be as effective as commercially available HDF machines. In this article, we will focus on the experience of HDF practice and barriers to adoption in developing countries. Results can guide clinical practice recommendations for implementing HDF in resource‐limited settings.
Research hotspots and emerging trends of automated peritoneal dialysis: A bibliometric analysis from 2000 to 2020
Authors: Tong Yan , Wang Hong , Cao Xueying , Cai Guangyan , Chen Xiangmei , Zhou Jianhui 
Published: March 2022

AbstractBackgroundThe implementation of automated peritoneal dialysis (APD) has considerably increased in many countries. We conducted a bibliometric analysis to evaluate the accumulating studies on APD in the last two decades quantitatively and qualitatively.MethodsPublications regarding APD research between 2000 and 2020 were retrieved from the Web of Science Core Collection database by using the index term “automated peritoneal dialysis.” CiteSpace, VOSviewer, and an online platform were employed to analyze the number of publications and the collaboration relationships between countries, institutions, authors, and co‐cited journals. Cluster analysis and burst keywords detection were performed on co‐cited references and keywords, respectively.ResultsWe obtained a record of 545 publications related to APD in total. The United States was the country that contributes most, and Baxter Healthcare Corporation was the leading institution. Peritoneal Dialysis International was the most active journals in this field. Claudio Ranco was the most productive author, and Simon J Davies ranked the first in the cited authors. Co‐cited reference cluster analysis and high frequency keywords showed that survival, ultrafiltration and peritonitis are continuous hot topics. While remote monitoring (RM) and telemedicine may be APD research frontiers according to burst keywords detection.ConclusionThis bibliometric study provides comprehensive overview on the publications of APD over the past two decades. These findings help to identify the hotspots and explore new directions for future research. RM has become an emerging trend in APD field.
TRUEE; a bioinformatic pipeline to define the functional microRNA targetome of Arabidopsis
Authors: Wong Gigi Y. , Millar Anthony A. 
Published: March 2022

SUMMARYCentral to plant microRNA (miRNA) biology is the identification of functional miRNA‐target interactions (MTIs). However, the complementarity basis of bioinformatic target prediction results in mostly false positives, and the degree of complementarity does not equate with regulation. Here, we develop a bioinformatic workflow named TRUEE (Targets Ranked Using Experimental Evidence) that ranks MTIs on the extent to which they are subjected to miRNA‐mediated cleavage. It sorts predicted targets into high (HE) and low evidence (LE) groupings based on the frequency and strength of miRNA‐guided cleavage degradome signals across multiple degradome experiments. From this, each target is assigned a numerical value, termed a Category Score, ranking the extent to which it is subjected to miRNA‐mediated cleavage. As a proof‐of‐concept, the 428 Arabidopsis miRNAs annotated in miRBase were processed through the TRUEE pipeline to determine the miRNA ‘targetome’. The majority of high‐ranking Category Score targets corresponded to highly conserved MTIs, validating the workflow. Very few Arabidopsis‐specific, Brassicaceae‐specific, or Conserved‐passenger miRNAs had HE targets with high Category Scores. In total, only several hundred MTIs were found to have Category Scores characteristic of currently known physiologically significance MTIs. Although non‐exhaustive, clearly the number of functional MTIs is much narrower than many studies claim. Therefore, using TRUEE to numerically rank targets  directly on experimental evidence has given insights into the scope of the functional miRNA targetome of Arabidopsis.
Minimising donor‐site morbidity following limbs' injuries with keystone perforator island flap reconstruction
Authors: Virág Timea H. , Muntean Maximilian V. , Georgescu Alexandru V. 
Published: March 2022

AbstractPlastic surgeons strive to choose better techniques to reconstruct the defects of the limbs, minimising the wound healing problems, improving the aesthetic and functional outcome with less complications. This study refers to the use of keystone perforator island flap (KPIF) in limbs' reconstruction, their harvesting technique to minimise donor‐site morbidity, maximise the functional and cosmetic outcome, and will point on the most important indications and advantages. Between January 2014 and June 2020, a number of 28 cases were treated in our department, with simple or complex defects of the limbs. The database included patients' demographics, comorbidities, aetiology, characteristics of the flap, surgical factors, follow‐up period and flap outcomes. We performed 28 KPIFs, 14 of type I, 12 of type IIA, 1 of type III, and 1 of type IV, with an average size of 69 cm2 (ranged from 1.25 cm2 to 318 cm2). Trauma was the major cause of the defects. One flap exhibited approximately 4% partial superficial necrosis. All donor sites healed without any adverse events. All patients were satisfied with the functional and aesthetic results. The KPIFs provide a simple and effective method of wound closure by using tissues of similar texture, thickness and colour. Preserving the main artery and the underlying muscle, this flap reduces the donor site morbidity. The use of KPIFs seems to be one of the most suitable choices whenever possible.
Experimental and CFD simulation of interactions between water droplets with different surface features to understand water droplet erosion
Authors: Jing Ming , Gujba Abdullahi K. , Medraj Mamoun 
Published: March 2022

Water droplet erosion (WDE) has received considerable attention in recent years. Different approaches have been proposed to understand WDE and find lasting solutions. Among them is understanding the interaction between the droplet impacts and the target surface, especially at the erosion initiation stage. For this reason, we studied the interactions between water droplets and different surface features to understand WDE. These surface features included flat smooth surfaces and grooved and porous samples. For the grooved samples, depths of 1.0 and 0.5 mm were studied and their WDE performance was evaluated. The 0.5 mm groove showed a longer incubation period than the flat reference sample. This work suggested that a thin water film is formed in the groove, which aids in dampening the impacts of subsequent water droplets. However, the maximum erosion rate is not affected by introducing these grooves. The WDE performance of the porous samples is better than that of the solid material. This is because the porous structure dissipates the impact energy of the water droplets. The simulation results were in agreement with the experimental observations in this work. Furthermore, the simulation showed that the water droplet impacting patterns on different surface features are attributed to the effect of radial and axial airflows.
Can electron and muon $$g-2$$ anomalies be jointly explained in SUSY?
Authors: Li Song , Xiao Yang , Yang Jin Min 
Published: March 2022

AbstractThe FNAL+BNL measurements for muon $$g-2$$

g
-
2

is $$4.2\sigma $$

4.2
σ

above the SM prediction, and the Berkeley $$^{133}$$

133

Cs measurement for the fine-structure constant $$\alpha _\mathrm{em}$$

α
em

leads to the SM prediction for electron $$g-2$$

g
-
2

which is $$2.4\sigma $$

2.4
σ

above the experimental value. Hence, a joint explanation of both anomalies requires a positive contribution to muon $$g-2$$

g
-
2

and a negative contribution to electron $$g-2$$

g
-
2

, which is rather challenging. In this work we explore the possibility of such a joint explanation in the minimal supersymmetric standard model (MSSM). Assuming no universality between smuon and selectron soft masses, we find out a part of parameter space for a joint explanation at $$2\sigma $$

2
σ

level, i.e., $$\mu M_1,\mu M_2<0$$

μ

M
1

,
μ

M
2

<
0

, $$m_{L1}, m_{E2}<200$$

m

L
1

,

m

E
2

<
200

GeV, $$m_{L2}$$

m

L
2

being much larger than the soft masses of other sleptons, $$|M_1|<125$$

|

M
1

|
<
125

GeV and $$\mu <400$$

μ
<
400

GeV. This part of parameter space can survive LHC and LEP constraints, but gives an over-abundance for dark matter if the bino-like lightest neutralino is assumed to be the dark matter candidate. With the assumption that the dark matter candidate is a superWIMP (say a pseudo-goldstino in multi-sector SUSY breaking scenarios, whose mass can be as light as GeV and produced from the late-decay of the thermally freeze-out lightest neutralino), the dark matter problem can be avoided. So, we conclude that the MSSM may give a joint explanation for the muon and electron $$g-2$$

g
-
2

anomalies at $$2\sigma $$

2
σ

level (the muon $$g-2$$

g
-
2

anomaly can be even ameliorated to $$1\sigma $$

1
σ

).
Association of Brain Volumes and White Matter Injury With Race, Ethnicity, and Cardiovascular Risk Factors: The Multi‐Ethnic Study of Atherosclerosis
Authors: Austin Thomas R. , Nasrallah Ilya M. , Erus Guray , Desiderio Lisa M. , Chen Lin Y. , Greenland Philip , Harding Barbara N. , Hughes Timothy M. , Jensen Paul N. , Longstreth WT , Post Wendy S. , Shea Steven J. , Sitlani Colleen M. , Davatzikos Christos , Habes Mohamad , Nick Bryan R. , Heckbert Susan R. 
Published: March 2022

Background
Cardiovascular risk factors are associated with cognitive decline and dementia. Magnetic resonance imaging provides sensitive measurement of brain morphology and vascular brain injury. However, associations of risk factors with brain magnetic resonance imaging findings have largely been studied in White participants. We investigated associations of race, ethnicity, and cardiovascular risk factors with brain morphology and white matter (WM) injury in a diverse population.

Methods and Results
In the Multi‐Ethnic Study of Atherosclerosis, measures were made in 2018 to 2019 of total brain volume, gray matter and WM volume, and WM injury, including WM hyperintensity volume and WM fractional anisotropy. We assessed cross‐sectional associations of race and ethnicity and of cardiovascular risk factors with magnetic resonance imaging measures. Magnetic resonance imaging data were complete in 1036 participants; 25% Black, 15% Chinese‐American, 19% Hispanic, and 41% White. Mean (SD) age was 72 (8) years and 53% were women. Although WM injury was greater in Black than in White participants in a minimally adjusted model, additional adjustment for cardiovascular risk factors and socioeconomic status each attenuated this association, rendering it nonsignificant. Overall, greater average WM hyperintensity volume was associated with older age and current smoking (69% greater vs never smoking); lower fractional anisotropy was additionally associated with higher diastolic blood pressure, use of antihypertensive medication, and diabetes.

Conclusions
We found no statistically significant difference in measures of WM injury by race and ethnicity after adjustment for cardiovascular risk factors and socioeconomic status. In all racial and ethnic groups, older age, current smoking, hypertension, and diabetes were strongly associated with WM injury.
Maintenance of Western North Pacific Anomalous Anticyclone in Boreal Summer by Wind-Induced Moist Enthalpy Advection Mechanism
Authors: Wang Yiming , Wu Bo , Zhou Tianjun 
Published: March 2022

Abstract
The western North Pacific anomalous anticyclone (WNPAC) is the most important interannual circulation anomaly over the western Pacific warm pool. It can persist from boreal winter to the following summer and has great impacts on the East Asian monsoon. The maintenance of the WNPAC in boreal summer was explained by Ekman divergence anomalies over the western North Pacific (WNP) induced by the equatorial easterly Kelvin waves from the tropical Indian Ocean and the Maritime Continent. In this study, we propose a new mechanism for the maintenance of the WNPAC in the season, which we refer to as the “wind-induced moist enthalpy advection” (WIMEA) mechanism. Warm anomalies over the tropical Indian Ocean enhance local deep convection and thus excite atmospheric easterly Kelvin waves to the east. Climatological moist enthalpy decreases eastward over the WNP due to the local northward extension of the intertropical convergence zone (ITCZ) with the establishment of the WNP summer monsoon. Hence, the easterly anomalies transport low moist enthalpy (dry) air westward to the WNP. The induced negative moist enthalpy advection anomalies drive downward motion anomalies and thus suppress deep convection over the WNP under the constraint of the moist static energy budget balance. This moist teleconnection mechanism does not rely on Ekman processes. Numerical experiments using a dry linear baroclinic model indicate that the WIMEA and the conventional Kelvin wave–induced Ekman divergence mechanism have nearly equal relative contributions to the maintenance of the summer WNPAC, with the former mainly driven by the enhanced convection over the tropical Indian Ocean, while the latter is driven by that over the Maritime Continent.