bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh peningkatan suhu pada fase pembentukan umbi tanaman kentang (Solanum tuberosum) cv. Granola
Authors: Pantouw Carla Frieda , Hapsari Betalini Widhi , Hastilestari Bernadetta Rina 
Published: July 2022

Kentang (Solanum tuberosum) merupakan salah satu bahan makanan yang penting di dunia. Budidaya komoditas ini umumnya berada di dataran tinggi dengan suhu yang rendah. Jumlah lahan pertanian di dataran tinggi semakin kecil disebabkan antara lain karena alih fungsi lahan. Penanaman kentang di dataran yang lebih rendah menjadi kendala karena adanya peningkatan suhu. Penelitian ini dirancang untuk mengetahui pengaruh ketinggian tempat dan perubahan suhu terhadap tanaman kentang pada fase pembentukan umbi. Tanaman kontrol ditanam pada ketinggian 2921 meter diatas permukaan laut (m dpl) dengan suhu siang/malam (190C/120C). Setelah fase pembentukan umbi, sebagian tanaman dipindah ke daerah dengan ketinggian 115 m dpl dengan suhu siang/malam (300C/240C). Perubahan ketinggian tempat dengan suhu yang berbeda mengakibatkan shade avoidance, perubahan akumulasi biomasa pada batang tanaman dan penurunan hasil panen. Hal ini disebabkan karena penurunan hasil fotosintesa, sukrosa, serta kadar klorofil yang disebabkan oleh faktor genetik dan metabolisme enzim. Oleh karena untuk mendukung permintaan komoditas kentang yang semakin meningkat, pemuliaan tanaman kentang tahan terhadap cekaman suhu diperlukan untuk memperluas area penanaman kentang di dataran menengah maupun dataran rendah.ABSTRACTPotato (Solanum tuberosum) is one of the important staple foods in the world. This plant is mostly cultivated in high-altitude regions with low temperatures. As the number of lands for potato cultivation is getting smaller due to land conversion. Potato cultivation in low-altitude regions with high temperatures yields low productivity. This study was designed to determine the effect of altitude and temperature changes on potato plants in the tuber formation phase. Control plants were planted in an area with an altitude of 2921 meters above sea level (m asl), with day/night temperatures (190C/120C). After the tuber formation phase, some plants were transferred to areas with an altitude of 115 m above sea level and day/night temperatures (300C/240C). Change in altitude with different temperatures resulted in shade avoidance, changes in the accumulation of biomass on plant stems, and yield reduction. This is due to decreasing sucrose content as photosynthesis assimilates, and chlorophyll content due to genetic factors and enzyme metabolism. Therefore, to support the increasing demand for potato commodities, breeding potato plants resistant to heat stress is needed to expand the potato planting area in middle or low altitudes.
Tale of two rhinos: isotopic ecology, paleodiet, and niche
differentiation of Aphelops and Teleoceras from the Florida
Neogene
Authors: MacFadden Bruce J. 
Published: August 2022

Abstract
Carbon (δ13C) and oxygen
(δ18O) isotopic results are presented from 42 tooth
enamel carbonate samples of rhinos (Family Rhinocerotidae) from a sequence
of Florida Neogene localities between 9.5 and 4.5 Ma. These data are used to
interpret ancient diets and test previous hypotheses of terrestrial/aquatic
adaptations of two sympatric rhinos, Aphelops and
Teleoceras. The long-limbed, shorter-crowned
Aphelops traditionally has been reconstructed
as an open-country browser (similar to the modern black rhino), whereas
short-limbed, higher-crowned Teleoceras
traditionally has been reconstructed as an amphibious grazer (similar to the
modern hippo). Between about 9. 5 and 7 Ma the δ13C
values (all <−11.0‰) from Florida Aphelops and
Teleoceras indicate that both rhinos were
feeding on C3 plants. This diet probably included a
combination of browse and C3 grasses, although the
exact proportions for each genus cannot be distinguished isotopically. In
contrast, after the late Miocene global carbon shift as represented at 4.5
Ma in Florida, Aphelops was a browser (mean
δ13C = −11.9‰), whereas
Teleoceras was a mixed
feeder/C4 grazer (mean δ13C =
−7.0‰). Oxygen isotopic values indicate that neither
Aphelops nor
Teleoceras was principally aquatic. Given
these new isotopic data, more plausible modern analogs for these two extinct
rhinos are, respectively, the terrestrial browsing black rhino
(Diceros bicornis) and the terrestrial
grazing white rhino (Ceratotherium simum), which
are sympatric today in Africa.
Management of oncological and emergency surgery cases during COVID-19 pandemic
Authors: DAL M. Burak , UĞUR Mustafa , DUYMUŞ Mehmet Esat , TEMİZ Muhyittin 
Published: July 2022

Amaç: Acil cerrahi vakalara Genel Cerrahide önemli bir yer tutmaktadır. COVID-19 salgını döneminde, hastaların salgından etkilenme korkusu ve davranış şekillerinin karmaşıklığı bu hastalıkların teşhis ve tedavisini zorlaştırmaktadır.
Yöntem: Üçüncü basamak olan merkezimizde, COVID pandemisi sırasında akut apandisit, kolesistit ve kolorektal kanser tanısı ile cerrahi geçiren hastaların bilgisayarlı veri tabanı retrospektif olarak pandemi öncesi ve pandemi dönemi şeklinde gözden geçirildi.
Bulgular: Çalışma süresi boyunca 1100 hasta apandisit, 500 hasta kolesistit, 120 hasta onkolojik hastalıklar nedeni ile ameliyat edildi. Ortalama yaş her iki dönem için benzerdi, pandemi öncesi dönemde 34.06 ± 16.7 pandemi döneminde 36,72 ± 15,31 yaş ortalaması mevcuttu. Semptom başlaması ile hastaların hastaneye başvuru süreleri her iki döneme benzerdir (34,55 ± 31,51 ile 34,35 ± 37,94 sa, P = 0,968). Laboratuvar testler arasında anlamlı bir farklılık göstermemiştir. WBC değerleri pandemi öncesi dönemde 12.73 ± 4.3 × 103 idi pandemi sonrası dönemde 13.62 ± 4.62×103 (P = 0.1308) idi. Pandemi öncesi ve pandemi döneminde tüm hastalar en az 1 görüntüleme yöntemi kullanılmıştır.
Sonuç: COVID-19 pandemisinin ilk aşamasında, komplike acil cerrahi gereksinimi oranında önemli bir artış vardı. Hastalar bundan kaçınmaları için semptomların başlaması ile acil polikliniklere başvurmaları şiddetle teşvik edilmelidir.
The expression of Beta-Catenin and Sox2 in adenocarcinoma and adenomatous polyps of the colon and their association with clinicopathological parameters
Authors: GÜNEY Neslihan , GÜRSES İclal , SERİNSÖZ LİNKE Ebru , GÜRSOY Didar , ÜÇBİLEK Enver , ÇOLAK Tahsin 
Published: July 2022

Objective: Our aim was to investigate the immunohistochemical expression of β-catenin and Sox-2 in adenomatous polyps and adenocarcinoma of colon and also to evaluate the effects of these markers in adenoma-carcinoma sequence and their association with clinicopathological parameters.
Methods: Fifty-six tubular adenomas with low grade dysplasia (TALGD), 53 tubular adenomas with high grade dysplasia (TAHGD), 44 tubulovillous adenomas (TVA), 29 villous adenomas (VA) and 60 adenocarcinomas were included in the study. The nuclear staining of Sox2 was evaluated as well as both nuclear and cytoplasmic stainings of β-catenin. A semiquantitative scoring was performed. The results were compared between the groups and the relationship of the results with clinicopathological parameters was evaluated.
Results: Nuclear and cytoplasmic β-catenin expressions of the adenocarcinomas were higher than polyps. The expressions in the VA and TVA polyp groups were higher than the expressions in TAHGD and TALGD, respectively. Membranous β-catenin expression in the adenocarcinoma was higher than the polyps except VA. The evaluation between polyp groups with respect to membranous β-catenin staining revealed a statistically significantly difference in favor of VA compared with TVA, TAHGD and TALGD; in favor of TAHGD compared with TVA, in favor of TVA compared with TALGD while it was found statistically significantly higher in TAHGD than TALGD.
Conclusion: The results regarding β-catenin expression of the polyp groups were consistent with the literature. There was a positive correlation between β-catenin expression (nuclear and cytoplasmic) and malignancy. High Sox2 expressions were found correlated with malignancy potential. Large sampling size investigations to be supported by further molecular studies are needed to clarify the effect of Sox2 expression in the sequence of adenoma-carcinoma comprehensively.
Diagnostic value of fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography in the postoperative clinical management of patients with colorectal cancer
Authors: ÇINAR Alev , ALAGÖZ Engin , AYAN Aslı , UÇGUN Aybüke 
Published: July 2022

Objective: Colorectal cancer (CRC) is a well-known, surgically curable type of cancer if detected early. Survival rate increase depends on the early detection of the recurrent lesions. In this present study, we aimed to emphasize the value of the F-18 FDG PET/CT imaging modality to evaluate the postoperative treatment response of patients with CRC, based on our clinical experience.
Methods: Between January 2016 and January 2020, 168 colorectal cancer patients underwent F-18 FDG PET/CT to evaluate residue/recurrence cancer in our institution. Patients enrolled in this study were operated on for primary colon tumors. Before and after systemic therapy, all patients underwent pre and post-treatment F-18 FDG PET/CT to assess treatment response. The images were analyzed retrospectively.
Results: Patients were classified according to primary tumor localization. Of 168 patients, the primary tumor localized in the ascending colon (n=55), the descending colon (n=33), the transverse colon (n=14), the rectosigmoid (n=61), and the caecum in the other five patients. Recurrence of primary tumor site was detected in 57 patients; 33 of them were male (57.9%) and 24 female (42.1%). The mean SUVmax of the local recurrent lesion was 8.97 ± 3.42 g/ml. In addition, from the ascending colon group, two patients had new foci of tumoral lesions (1.20%).
Conclusion: Resection of the colonic segments with tumor, if possible, is the first step in the treatment of patients with colorectal cancer. After the curative operation, recurrence can be seen in approximately 40% of patients within the first two years. Early detection of recurrence improves the survival rate.
The Adoption of Artificial Intelligence in Newsrooms in Kenya: a Multi-case Study
Authors: Kioko Peter Mwangangi , Booker Nancy , Chege Njoki , Kimweli Paul 
Published: July 2022

The deployment of Artificial Intelligence (AI) in newsrooms is gaining prominence worldwide, with the technology being used to enhance the processes of news gathering, packaging, and distribution. The study was guided by two research questions: what factors drive/hinder(s) the adoption of AI or lack of it in newsrooms in Kenya? Moreover, what opportunities do journalists feel are offered by adopting AI in newsrooms in Kenya? A qualitative research approach and descriptive research design were employed to investigate the adoption of AI in newsrooms in Kenya. British Broadcasting Corporation (BBC-Africa) and Radio Africa Group (RAG) media organizations were the target population. As a research strategy, a multi-case method was employed. The researchers conducted in-depth interviews with newsroom-based participants. A purposive sampling technique was used to select participants for the research. Collected data were analyzed thematically. The paper identified six factors driving the adoption of AI or lack of it: management buy-in, cost, technical skills, clarity of user case, perception, and company structure. Further, the study identified three challenges presented by adopting AI: lack of quality data, ethical concerns, and unpredictability of the technology’s impact. The study concludes that AI offers excellent opportunities for newsrooms in Kenya to explore. Still, some obstacles need to be addressed before they can benefit fully from the technology. The study projects that human and automated journalism will become closely integrated in the future and recommends that newsrooms in Kenya prepare to embrace AI by laying the foundation for its adoption. Media schools should update curricula to prepare journalists to work with emerging technologies such as AI. Further research is needed to identify the specific skill sets required for Kenyan digital journalists to embrace AI fully. Scholars should investigate how AI can shape new business models given shrinking revenues in the media.
Etude qualitative de la relation entre les Pratiques de Management du Capital Humain et l’Engagement Organisationnel : cas des Professionnels de la Santé Publique
Authors: El Ammary Houda , Balhadj M. Said 
Published: July 2022

L’objectif de cette réflexion est de proposer un inventaire des variables explicatives de l’engagement organisationnel en termes de pratiques de Management du Capital Humain offertes, ainsi que de ceux dont le personnel soignant souhaiterait disposer dans leur organisation. Dans ce sens, une étude qualitative exploratoire a été réalisée auprès de 23 professionnels de la santé publique pour présenter un modèle des pratiques du management de capital humain susceptibles d’influencer l’engagement organisationnel. Le traitement des entretiens semi-directifs a été réalisé sous le logiciel Nvivo 10, à travers une analyse de contenu thématique. Compte tenu des résultats, la caractéristique la plus marquante de cette étude est l’apparition du climat d’éthique comme un antécédent de l’engagement organisationnel.

This paper focuses on proposing an inventory of the explanatory variables of organizational commitment in terms of Human Capital Management practices offered, as well as those that the nursing staff would like to have in their organization. An exploratory qualitative study was carried out with 23 public health professionals. This study presented the main human capital management practices likely to influence organizational commitment. The processing of the semi-directive interviews was carried out using the Nvivo 10 software through a thematic content analysis. Considering the results, the most striking feature of this study is the appearance of ethical climate as an antecedent of organizational commitment.
Evaluación del posicionamiento preciso a través de los receptores GPS LEA-6T, NEO-M8T y ZED-F9P de bajo costo
Authors: Bojorquez-Pacheco Naccieli , Romero-Andrade Rosendo , Trejo-Soto Manuel E. , Hernández-Andrade Daniel , Trejo-Echeagaray Manuel 
Published: July 2022

Se comparó el posicionamiento obtenido en dos casos de estudios dependientes de las distancias (~31 y ~4.9 Km) a través del método estático mediante el uso de receptores de bajo costo de simple (LEA-6T y NEO-M8T) y doble frecuencia (ZED-F9P); tomando como referencia un receptor de orden geodésico Geomax Zenith 25. Asimismo, el posicionamiento fue evaluado con a la normativa vigente en México para el Circulo de Error Probable (CEP) y Exactitud Posicional Vertical (EPV) con una incertidumbre del 95%. Seencuentran discrepancias entre coordenadas para un mismo punto en el sistema ENU, valores mínimos de ~ 2 mm y ~ 10 mm, para una distancia ~31 y ~4.9 Km, respectivamente, obteniendo el mejor resultado con el receptor de una frecuencia LEA-M8T para la distancia de ~31 km; para el caso ~4.9 km se presenta con el receptor ZED-F9P en conjunto con una antena de orden Geodésico. Por otro lado, los resultados muestran un grado de cumplimiento en el posicionamiento de los receptores de bajo costo favorable donde; se obtienen valores de 8 mm de variación máxima para CEP; para EPV al 95% de confiabilidad, 1 cm de discrepancia. Presentando los mejores resultados los receptores LEA-6T y NEO-M8T, caso ~31 km, en cuanto a CEP y EPV.

A comparative study between the positioning obtained in two case studies depending on distances (~31 and ~4.9 km) was carried out through the static method of survey using the low-cost receivers of single (LEA-6T and NEO-M8T) and double frequency (ZED-F9P). The reference was taken as Geomax Zenith 25 geodetic order receiver. The positioning was evaluated with the current regulations in Mexico for the Circle of Probable Error (CEP) and Vertical Positional Accuracy (EPV) with an uncertainty of 95%. The discrepancies between coordinates for the same point in the ENU system were found to be the minimum values of ~ 2 mm and ~ 10 mm for a distance of ~31 and ~4.9 Km, respectively. The best results were obtained with the NEO-M8T single frequency receiver for the distance of ~31 km and for the distance of ~4.9 km, it is presented with the ZED-F9P receiver in conjunction with a geodetic antenna. Whereas on the other hand, the results show a degree of compliance in the positioning of low-cost receivers wherein the variation values of a maximum of 8 mm are obtained for CEP and for EPV 1 cm discrepancy was observed at 95% reliability. The LEA-6T and NEO-M8T receivers presented the best results for the case of ~31 km, in terms of CEP and EPV.
Mid-Borderline Leprosy with Mild Type 1 Reaction in Children: A Case Report
Authors: Indraswari Anindia , Listiawan Muhammad Yulianto 
Published: August 2022

Background: Leprosy is a chronic infectious disease caused by Mycobacterium leprae. Cases of leprosy in children are rarely found because of the long incubation period of Mycobacterium leprae. Purpose: To report a case of mid-borderline leprosy with a mild type 1 reaction in a seven-years-old girl patient. Case: A 7-years-old girl patient presented with multiple red and white patches on her face, body, arms, legs, and buttocks since 6 months before. There was no itching, numbness, painr fever. There was no thickening of peripheral nerves and no nerve function impairment. Her grandmother was suspected to have leprosy, but she had never been treated and had already passed away. From the acid fast bacilli (AFB) examination, the bacterial index (BI) was 1+ and the morphological index (MI) was 2%. A serologic test examination was also performed and the result were Immunoglobulin (Ig) G 3716 u/ml and IgG 284 u/ml. The patient got multidrugs therapy for 12 months and after 9 months of treatment, the pre-existing patches became erythematous, thickened, and felt pain when touched, but there was no fever. In the presence of pain, oral ibuprofen was then administered and the patches began to improveDiscussion: Due to the possibility of leprosy reaction, it is important to immediately give prompt treatment to children with type 1 leprosy reaction that is associated with neuritis and leads to deformities. Conclusion: Early diagnosis and therapy for a type 1 leprosy reaction are very important to prevent deformities.
Permodelan kerawanan tanah longsor di Kecamatan Ngargoyoso, Kabupaten Karanganyar
Authors: Hartono Muhammad Arief , Utomo Rizon Pamardhi , Miladan Nur 
Published: July 2022

<pre>Kecamatan Ngargoyoso merupakan kecamatan dengan jumlah peristiwa kejadian tanah longsor terbanyak di Kabupaten Karanganyar. Dalam Rencana Tata Ruang Wilayah (RTRW) Kabupaten Karanganyar 2011-2031, terdapat peta kerawanan tanah longsor yang digunakan sebagai dasar untuk melakukan tindakan penanganan kejadian bencana tanah longsor. Namun, peta kerawanan yang terdapat dalam RTRW terlihat mengelompok dan tidak menunjukkan kenampakan fisik alam yang beragam. Ketelitian peta tersebut kurang baik sebagai dasar mitigasi pra-bencana tanah longsor di Kecamatan Ngargoyoso. Penelitian ini bertujuan untuk membangun permodelan kerawanan bencana tanah longsor di Kecamatan Ngargoyoso, Kabupaten Karanganyar. Peneliti menggunakan permodelan yang dibangun menggunakan teknik overlay dari enam variabel, yaitu kemiringan lereng, jenis tanah, struktur batuan, lokasi patahan, curah hujan, dan tutupan vegetasi. Hasil dari permodelan ini membagi kerawanan menjadi tiga kategori, yakni kerawanan rendah, sedang dan tinggi. Kategori kerawanan rendah hanya mencakup 54,87 hektar, kerawanan sedang mendominasi dengan luasan 4236,62 hektar, dan kerawanan tinggi mencakup 1657,54 hektar. Kerawanan tinggi tersebar di bagian timur Kecamatan Ngargoyoso, sedangkan lokasi yang memiliki tingkat kerawanan sedang dan rendah tersebar di seluruh desa di Kecamatan Ngargoyoso. Terdapat perbedaan yang signifikan antara peta kerawanan dari dokumen RTRW dengan peta hasil dari permodelan. Lokasi kerawanan pada peta kerawanan RTRW terlihat mengelompok, sedangkan peta hasil permodelan memperlihatkan bahwa lokasi tingkat kerawanan tanah longsor tersebar dan disesuaikan dengan kondisi lapangan. Oleh karena itu, hasil dari permodelan dapat dianggap lebih detail dan mendekati realita.</pre>
Women's Participation in the Health Workforce in Fragile and Conflict-Affected Countries: Application of a Gender Analysis Framework
Authors: Ayaz Basnama , Hall Linda McGillis , Martmianakis Maria Athina , Muntaner Carles , Burnside Heather , Nelson Sioban 
Published: August 2022

Abstract
BackgroundGender analysis is a process for assessing the impact of several development activities in the healthcare system on individual women, men, and other genders. Several gender analysis frameworks guide to undertake gender analysis in planning, implementing, and evaluating the impact of the various development initiatives, ranging from humanitarian assistance to a broader socio-economic development in the context, including the progress towards gender equality in access to and control over resources, and changes in gender relation. MethodsWe applied a gender analysis framework (GAF) proposed by Morgan and colleagues to the empirical literature on women's participation in the health workforce. The GAF guided analysis of the gendered dynamics among males and females between and within medicine, nursing, and midwifery professionals in the human resources for health (HRH) in fragile and conflict-affected states/countries (FCASs).Results Analysis revealed strong gendered patterns influenced unequal access to resources, division of labor, social norms, ideologies and beliefs, and rules and decision making, which disproportionately affected more women than men in FCASs. Based on the findings, we recommend governments in FCAS offer equal opportunities for both the male and female health workforce to address their practical needs as beneficiaries to improve their living conditions and address strategic needs, particularly empowering women and transforming their position in society. Similarly, gender equality must be considered more centrally in health systems research to reinforce transformative social and political interventions empirically from the conception of the research idea, the participation in the processes as participants and researchers to achieve the intended outcomes. Conclusion The gender analysis framework helped analyze gender power dynamics between males and females in the health workforce in different FCASs that affected women's access to resources, role performance, values, and perspectives, and decision making, which have implications for reinforcing equal opportunities for males and females in the workforce and the health systems research.
Mucins form a nanoscale material barrier against immune cell attack
Authors: Park Sangwoo , Colville Marshall , Shurer Carolyn , Huang Ling-Ting , Kuo Joe , Paek Justin , Goudge Marc , Su Jin , DeLisa Matthew , Lammerding Jan , Zipfel Warren , Fischbach Claudia , Reesink Heidi , Paszek Matthew 
Published: August 2022

Abstract
The cancer cell glycocalyx serves as a major line of defense against immune surveillance. However, how specific physical properties of the glycocalyx are regulated and contribute to immune evasion is not well understood. Here, we uncover how the surface density, glycosylation, and crosslinking of cancer-associated mucins contribute to the nanoscale material thickness of the glycocalyx, and further analyze the effect of the glycocalyx thickness on resistance to effector cell attack. Natural Killer (NK) cell-mediated cytotoxicity exhibits a near perfect inverse correlation with the glycocalyx thickness of target cells regardless of the specific glycan structures present, with changes in the glycocalyx thickness of approximately 10 nanometers significantly altering susceptibility to NK attack. Equipping the NK cell surface with a mucin-digesting enzyme can improve killing with a performance enhancement that can rival or exceed chimeric antigen receptors (CARs). Together, our results motivate the development of glycocalyx-editing immune cells for cancer immunotherapy.