bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhancing the Quality of User Research Using Embedded IoT Sensors for Collecting Life Information
Authors: Tanaka T. , Taoka Y. , Saito S. 
Published: May 2022

AbstractThis study aims at developing a new user research method that uses IoT sensors embedded at users' homes to enable users to recall their memories. The proposed method was evaluated by experiments where four participants individually created user journey maps with quantity data that was collected for seven days. The results showed that IoT sensor data increased the quantity, clarity, and accuracy of recalled memories. This study argues that IoT sensors can be an effective approach to increasing user research quality by triggering users' memories without interfering with users' ordinary lives.
The Use of Function Modelling Methods in Industry: Insights from a Large Scale Study with an Automotive OEM
Authors: Yildirim U. , Campean F. , Uddin A. 
Published: May 2022

AbstractThis paper presents an evaluation study for the System State Flow Diagram function modeling framework based on a large-scale study with an automotive OEM. Technical reports are used to evaluate the usage of the framework within the organization. The paper also introduces a list of the type of problems that engineers are interested in in practical function modelling. The findings suggest that there is a widespread uptake of the framework across the organization and it supports the usage of relevant key engineering tools within the context of a broader model-based Failure Mode Analysis methodology.
Identifying Factors Influencing the Design of a Suitable Knowledge Base in Product Engineering Projects
Authors: Kempf C. , Sanke F. , Heimicke J. , Rapp S. , Albers A. 
Published: May 2022

AbstractDuring product engineering, engineers draw on existing knowledge as a basis. This knowledge is applied in design processes either by adopting elements, alternating some attributes, or changing the solution principles. While concepts for design reuse exist, the proactive design of a suitable knowledge base is still a challenge. In this paper, we show influencing factors in engineering and their influence on the knowledge base. These factors are of the areas market, company, project, and team. Based on our results, we intent to develop a support for engineers to set up the knowledge base.
How to Assess a Creativity Session
Authors: Coustillac L. , Bazzaro F. , Lobbé J. , Meyer Y. 
Published: May 2022

AbstractTo renew their innovation and creativity practices, companies are now equipping themselves with new specific places: innovation laboratories. These laboratories support project teams during creativity sessions to generate ideas. In order to improve these practices, it is necessary to be able to assess and compare the different sessions organised. By joining the Clean Mobility Lab of Faurecia, we were able to analyse, observe and participate in creativity sessions. This immersion allowed us to develop an assessment grid of forty-eight indicators covering the entire creativity process.
The Inclusive Design Canvas. A Strategic Design Template for Architectural Design Professionals
Authors: Zallio M. , Clarkson P. J. 
Published: May 2022

AbstractDesigning accessible and inclusive buildings is essential if they are to provide enjoyable and inspiring experiences for all their occupants. Research revealed that many architectural design professionals perceive a lack of awareness of the aspects to consider when designing to be a limiting factor in the uptake of Inclusive Design. By involving expert stakeholders this study provides evidence for the demand to create an Inclusive Design Canvas, a strategic design template offering an educational springboard for building industry professionals to embed Inclusive Design in the design process.
An Attempt to Grasp Resonance during Co-Creation with Biosignal Indicators
Authors: Matsumae A. , Shoji K. , Motomura Y. 
Published: May 2022

AbstractResonance is known as an important phenomenon where individual creative moments resonate with each other during co-creation. The purpose of this study is to capture this co-creative moment as a resonant cognitive status with biosignal indicators. The authors conducted an experiment in which pairs of participants work on concept generation from two nouns and measured their dynamic creative status both subjectively and objectively with biosignal indicators fEMG and EOG. This study will help to understand co-creative cognitive phenomena and to improve the co-creative design process.
Designing Long-Lasting Products: Barriers for Design Consultancies
Authors: Bendixen A. F. , Jensen C. N. , Schmidt F. , Laursen L. N. 
Published: May 2022

AbstractPast research shows there are significant barriers for creating long lasting products. In this paper we examine, the distinct collaborative barriers design consultancies face when striving to design long-lasting products for client firms. Data is collected through case studies (four months of observations and interviews) from three projects. Through the study we find indications, that the value chain intricacies, provide distinct interfirm barriers for creating long lasting products. These barriers include vision clashes, misalignment in the aspired manufacturing quality and price position.
Cardiometabolic effects of earlyv. delayed time-restricted eating plus energetic restriction in adults with overweight and obesity: an exploratory randomised clinical trial
Authors: Queiroz Jéssica do Nascimento , Macedo Rodrigo Cauduro Oliveira , dos Santos Gabriela Cristina , Munhoz Samuel Vargas , Machado Carlos Leonardo Figueiredo , de Menezes Rodrigo Leal , Menzem Elisa Nascimento , Moritz Cesar Eduardo Jacintho , Pinto Ronei Silveira , Tinsley Grant M. , de Oliveira Alvaro Reischak 
Published: May 2022

AbstractThis exploratory study investigated the effects of earlyv. delayed time-restricted eating (TRE) plus caloric restriction (CR) on body weight, body composition and cardiometabolic parameters in adults with overweight and obesity. Adults (20–40 years) were randomised to one of three groups for 8 weeks: early time-restricted eating (eTRE; 08.00–16.00) plus CR, delayed time-restricted eating (dTRE; 12.00–20.00) plus CR or only CR (CR; 08.00–20.00). All groups were prescribed a 25 % energy deficit relative to daily energy requirements. Thirteen participants completed the study in the eTRE and CR groups and eleven in the dTRE group (n37). After the interventions, there was no significant difference between the three groups for any of the outcomes. Compared with baseline, significant decreases were observed in the body weight (eTRE group: −4·2 kg; 95 % CI, −5·6, −2·7; dTRE group: −4·8 kg; 95 % CI, −5·9, −3·7; CR: −4·0 kg; 95 % CI, −5·9, −2·1), fat mass (eTRE group: −2·9 kg; 95 % CI, −3·9, −1·9; dTRE group: −3·6 kg; 95 % CI, −4·6, −2·5; CR: −3·1 kg; 95 % CI, −4·3, −1·8) and fasting glucose levels (eTRE group: −4 mg/dl; 95 % CI, −8, −1; dTRE group: −2 mg/dl; 95 % CI, −8, 3; CR: −3 mg/dl; 95 % CI, −8, 2). In a free-living setting, TRE with a energetic deficit, regardless of the time of day, promotes similar benefits in weight loss, body composition and cardiometabolic parameters. However, given the exploratory nature of our study, further investigation is needed to confirm these findings.
Use of the Portsmouth Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (‘P-POSSUM’) to predict morbidity in patients undergoing surgery with reconstruction for temporal bone malignancy
Authors: Jones H , Gendre A , McHugh A , Hintze J , O'Sullivan B , Martin F , McConn-Walsh R , O'Neill J P , Shine N 
Published: May 2022

AbstractObjectiveThe Portsmouth Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity (‘P-POSSUM’) is a two-part scoring system that includes a physiological assessment and a measure of operative severity. This study sought to determine whether risk estimates for this scoring system could be used in major head and neck reconstructive surgery.MethodA retrospective review was performed of patients undergoing resection for a temporal bone malignancy in a single head and neck centre in Dublin, Ireland, from 2002 to 2021.ResultsThe mean ± standard deviation morbidity estimate calculated using the scoring system was 47.6 per cent ± 19.5 per cent. The actual rate of complications was 47 per cent. The optimal cut-off for the scoring system was calculated using the Youden index from the receiver operating characteristic curve, which was 40.5 per cent in this case.ConclusionThe study indicates that the Portsmouth Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity is a useful tool for predicting morbidity risk in patients undergoing head and neck resection with reconstruction for temporal bone malignancies.
Morphological Aspects and Microscopic Analyses of Fibrous Tunic and Uveal Components in Bovine Eye
Authors: Ertaş Tuba Damla , Kahvecioğlu Kifayet Oya , Erdoğan Serkan 
Published: May 2022

AbstractThis study aimed to reveal the anatomical features of the bovine eye by scanning electron and light microscopic methods. For this purpose, a total of 40 eyes were evaluated. Gross and microscopic characteristics of the cornea, sclera, ciliary body, choroid, iris, and lens were determined. Bowman's and Descemet's membranes of the cornea were quite dense and prominent. Collagen lamellae of the cornea were wavy in the periphery and more parallel to the basal and metachromatic fibroblasts were noted. Three to four ciliary plicae merged to form ciliary processes. The presence of prominent intermediate bands connecting the ciliary plicae was determined. The zonular fibrils merged and attached to the lens in the form of thick zonular bands. A dense corpora nigra was present at the rectangular pupillary border of the iris. Tapetum fibrosum, consisting of polygonal tapetal cells, was in blue-yellow-green color and covered most of the choroid. A complex drainage system consisting of trabecular meshwork, angular aqueous plexus, ciliary sinus, and scleral venous vessels localized in a fairly wide iridocorneal angle was identified. Identifying structural features of the bovine eye is very important and useful for pathological evaluations, understanding species-specific physiological mechanisms and for operative interventions of ruminant species.
Intergenerational effects of prenatal hypoxia exposure on uterine artery adaptations to pregnancies in the female offspring
Authors: Wooldridge Amy L. , Hula Nataliia , Kirschenman Raven , Spaans Floor , Cooke Christy-Lynn M. , Davidge Sandra T. 
Published: May 2022

AbstractPrenatal hypoxia is a common complication of pregnancy and is associated with detrimental health outcomes, such as impaired cardiac and vascular function, in adult offspring. Exposure to prenatal hypoxia reportedly impacts the reproductive system of female offspring. Whether exposure to prenatal hypoxia influences pregnancy adaptations and outcomes in these female offspring is unknown. We hypothesised that prenatal hypoxia impairs uterine artery adaptations in pregnancies of the adult offspring. Pregnancy outcomes and uterine artery function were assessed in 14–16 weeks old non-pregnant and late pregnant (gestational day 20; term = 22 days) adult female offspring born to rats exposed to prenatal normoxia (21% oxygen) or hypoxia (11% oxygen, between days 15–21 of gestation). Compared with normoxia controls, prenatal hypoxia was associated with pregnant adult offspring having reduced placental weights in their litters, and uterine artery circumferential stress that increased with pregnancy. Overall, prenatal hypoxia adversely, albeit mildly, compromised pregnancies of adult offspring.
Development and psychometric validation of new questionnaires assessing experienced discrimination and internalised stigma among people with Covid-19
Authors: Bonetto Chiara , Pace Davide , Bodini Luca , Colombi Morena , Van Bortel Tine , Lasalvia Antonio 
Published: May 2022

Abstract

Aims
To develop and validate two new standardised measures assessing, respectively, experienced discrimination (Covid-19 Experienced DISCrimination scale, CEDISC) and internalised stigma (COvid-19 INternalised Stigma scale, COINS) in people who had been infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or had developed coronavirus disease 2019 (Covid-19) disease.

Methods
Both the CEDISC and the COINS were developed in Italian and tested for ease of use, comprehension, acceptability, the relevance of items and response options within a focus group session. Online cross-sectional validation survey was conducted among adults infected with SARS-CoV-2 or who developed Covid-19 disease, members of a closed Facebook discussion group in Italy. Exploratory factor analysis (EFA) with Promax oblique rotation; the Kaiser-Meyer-Olkin (KMO) measure of sampling adequacy and the Bartlett's test of sphericity were used to assess the suitability of the sample for factor analysis. Reliability was assessed as internal consistency using Cronbach's alpha and as test–retest reliability using weighted kappa and intraclass correlation coefficient (ICC). Precision was examined by Kendall's tau-b coefficient.

Results
Overall, 579 participants completed the CEDISC, 519 also completed the COINS, 155 completed the retest for both scales after two weeks. The 12 items of the CEDISC converged over a 2-factor solution (‘social life’ and ‘close relations’) accounting for 49.2% of the variance (KMO = 0.894; Bartlett's test p < 0.001); the 13 items of the COINS converged over a 3-factor solution (‘self-perception’, ‘close relations’ and ‘social life’) accounting for 67.7% (KMO = 0.827; Bartlett's test p < 0.001). Cronbach's α was 0.848 for the CEDISC, and 0.837 for the COINS. The CEDISC showed three items (25%) with kappa between 0.61 and 0.80 and seven (58.4%) between 0.41 and 0.60, with only two items scoring 0.21 and 0.40; the COINS had ten items (76.9%) with kappa ranging from 0.41 to 0.60, and three items below 0.31. ICC was 0.906 (95% CI, 0.871–0.932) for the, CEDISC and 0.860 (95% CI, 0.808–0.898) for the COINS. Kendall's tau-b ranged from 0.360 to 0.556 (p < 0.001) for the CEDISC and from 0.290 to 0.606 (p < 0.001) for the COINS.

Conclusions
Both the CEDISC and the COINS are two valid and reliable scales to be used in studies examining the role of stigma and discrimination of people infected with SARS-CoV-2 and Covid-19 patients, and in research evaluating interventions designed to mitigate stigma in this population.
On the Variability of Floc Characteristics in a Shallow Estuary
Authors: Egan Galen , Chang Grace , Manning Andrew J. , Monismith Stephen , Fringer Oliver 
Published: May 2022

AbstractWe conducted field work in South San Francisco Bay to examine cohesive sediment flocculation dynamics in a shallow, wave‐ and current‐driven estuarine environment. Drawing on data collected using a suite of acoustic and optical instrumentation over three distinct seasons, we found that the factors driving floc size variability differed substantially when comparing locally sourced sediment (i.e., through wave‐driven resuspension) to suspended sediment advected from upstream. Statistical analysis of our extensive field data revealed additional seasonal variability in these trends, with wave stress promoting floc breakup during the summer and winter months, and biological processes encouraging floc growth during the spring productive period. Combining these data with fractal dimension estimates, we found that seasonally varying floc composition can lead to differences in floc settling velocity by a factor of approximately two to five for a given floc size. Finally, by analyzing co‐located turbulence and sediment flux measurements from the bottom boundary layer, we present evidence that the relationship between floc size and the inverse turbulent Schmidt number varies with floc structure. These results can be used to inform sediment transport modeling parameterizations in estuarine environments.
Mesoscale Moisture Transport in Determining the Location of Daytime Convection Initiations Clustered in Time and Space Over Southern China
Authors: Mai Chuying , Du Yu 
Published: May 2022

AbstractConvective initiation (CI) episodes are defined as a series of CIs that occur in clusters in time and space, and their prediction remains a challenge due to their complex mechanisms. In the present study, high‐resolution convection‐permitting simulations and observations were conducted to investigate the source of inhomogeneous instability for a cluster of daytime CIs gathering in a northeast‐southwest oriented region in South China where the convergence boundary for lifting was not evident. In the region of the CI episode, low‐level water vapor was enhanced significantly, which thus induced the heterogeneity of convective available potential energy. The enhanced moisture and instability in the CI episode region were caused by a mesoscale anticyclonic moisture channel. Mesoscale moisture transport formed under both the inertial oscillation of ageostrophic winds and the mesoscale high‐pressure disturbances in the daytime. The revealed mechanism is further confirmed by sensitivity experiments, where mesoscale anticyclonic transport is highly sensitive. Water vapor transport was affected by the evolution of mesoscale pressure disturbances and dominated the location and shape of the CI episode. Stronger mesoscale pressure disturbances resulted in the subsequent mesoscale anticyclonic airflow coming from various high‐pressure systems and conveying moisture farther east, and therefore, a CI episode occurred farther east by dozens to hundreds of kilometers. The climatology of the daytime CI episode also showed that the various mesoscale moisture transports confined moisture within the CI episode regions under weak convergence.
Effects of Formation Pathways and Bromide Incorporation on Jarosite Dissolution Rates: Implications for Mars
Authors: Zhou Di‐Sheng , Yu Xiao‐Wen , Chang Rui , Zhao Yu‐Yan Sara , Li Xiongyao , Liu Jianzhong , Lin Honglei , Qi Chao 
Published: May 2022

AbstractThe dissolution rates of jarosite can constrain the duration of aqueous activities on Mars. To date, few studies have considered the influences of formation pathways and anion substitutions on jarosite dissolution rates. Here, we investigated how the formation pathways (Fe(II)‐oxidation and Fe(III)‐forced hydrolysis) and incorporation of bromide influence the dissolution rates of K‐jarosite under eight aqueous conditions combining T (277 K, 298 K, and 323 K) and αw (0.35, 0.75 and 1), except for 277 K−0.35αw. The results show that jarosite dissolution rates are primarily influenced by aqueous T‐αw conditions. Formation pathways and Br contents are secondary factors and only become notable under low T (277 K) and low αw (0.35) conditions. Taking the jarosite formation pathways and Br incorporation into account, the maximum lifetime of jarosite may be slightly longer than that of the halogen‐free counterparts formed via Fe(III)‐forced hydrolysis. Jarosite of the Burns Formation (Meridiani Planum) and the Pahrump Hills member (Gale Crater) are likely formed via Fe(II)‐oxidation and halogen‐bearing. Their estimated field lifetime (∼150 μm–1 mm particles) in low‐T groundwater may last for hundreds of thousand years to a few million years. Jarosite in the Vera Rubin Ridge would share a similar lifespan if low‐T solutions account for jarosite formation and subsequent interactions; otherwise, interactions with hydrothermal fluids (∼100°C) would substantially shorten the jarosite lifetime. We conclude that Martian jarosite may survive continuous aqueous interactions for up to a few million years, indicating an extended duration of aqueous environments than previously thought.
Astronomical tuning of the Aptian stage and its implications for age recalibrations and paleoclimatic events
Authors: Leandro C. G. , Savian J. F. , Kochhann M. V. L. , Franco D. R. , Coccioni R. , Frontalini F. , Gardin S. , Jovane L. , Figueiredo M. , Tedeschi L. R. , Janikian L. , Almeida R. P. , Trindade R. I. F. 
Published: May 2022

AbstractThe Aptian was characterized by dramatic tectonic, oceanographic, climatic and biotic changes and its record is punctuated by Oceanic Anoxic Events (OAEs). The timing and duration of these events are still contentious, particularly the age of the Barremian-Aptian boundary. This study presents a cyclostratigraphic evaluation of a high-resolution multiproxy dataset (δ13C, δ18O, MS and ARM) from the Poggio le Guaine core. The identification of Milankovitch-band imprints allowed us to construct a 405-kyr astronomically-tuned age model that provides new constraints for the Aptian climato-chronostratigraphic framework. Based on the astronomical tuning, we propose: (i) a timespan of ~7.2 Myr for the Aptian; (ii) a timespan of ~420 kyr for the magnetic polarity Chron M0r and an age of ~120.2 Ma for the Barremian−Aptian boundary; and (iii) new age constraints on the onset and duration of Aptian OAEs and the ‘cold snap’. The new framework significantly impacts the Early Cretaceous geological timescale.
A topological refactoring design strategy yields highly stable granulopoietic proteins
Authors: Skokowa Julia , Hernandez Alvarez Birte , Coles Murray , Ritter Malte , Nasri Masoud , Haaf Jérémy , Aghaallaei Narges , Xu Yun , Mir Perihan , Krahl Ann-Christin , Rogers Katherine W. , Maksymenko Kateryna , Bajoghli Baubak , Welte Karl , Lupas Andrei N. , Müller Patrick , ElGamacy Mohammad 
Published: May 2022

AbstractProtein therapeutics frequently face major challenges, including complicated production, instability, poor solubility, and aggregation. De novo protein design can readily address these challenges. Here, we demonstrate the utility of a topological refactoring strategy to design novel granulopoietic proteins starting from the granulocyte-colony stimulating factor (G-CSF) structure. We change a protein fold by rearranging the sequence and optimising it towards the new fold. Testing four designs, we obtain two that possess nanomolar activity, the most active of which is highly thermostable and protease-resistant, and matches its designed structure to atomic accuracy. While the designs possess starkly different sequence and structure from the native G-CSF, they show specific activity in differentiating primary human haematopoietic stem cells into mature neutrophils. The designs also show significant and specific activity in vivo. Our topological refactoring approach is largely independent of sequence or structural context, and is therefore applicable to a wide range of protein targets.
Tailoring the superradiant and subradiant nature of two coherently coupled quantum emitters
Authors: Trebbia J.-B. , Deplano Q. , Tamarat P. , Lounis B. 
Published: May 2022

AbstractThe control and manipulation of quantum-entangled states is crucial for the development of quantum technologies. A promising route is to couple solid-state quantum emitters through their optical dipole-dipole interactions. Entanglement in itself is challenging, as it requires both nanometric distances between emitters and nearly degenerate electronic transitions. Here we implement hyperspectral imaging to identify pairs of coupled dibenzanthanthrene molecules, and find distinctive spectral signatures of maximally entangled superradiant and subradiant electronic states by tuning the molecular optical resonances with Stark effect. We demonstrate far-field selective excitation of the long-lived subradiant delocalized state with a laser field tailored in amplitude and phase. Optical nanoscopy of the coupled molecules unveils spatial signatures that result from quantum interferences in their excitation pathways and reveal the location of each emitter. Controlled electronic-states superposition will help deciphering more complex physical or biological mechanisms governed by the coherent coupling and developing quantum information schemes.