bluuebunny/crossref_metadata_2025_split huggingface dataset:
REKRUTMEN KARYAWAN BARU BERBASIS METODE ANALYTICAL HIERARCHY PROCESS (AHP)
Authors: Kurnia Dona 
Published: March 2022

Sistem pendukung keputusan kegiatan rekrutmen karyawan baru. Salah satu metode yang dapat digunakan adalah metode Analytical Hierarchy Process (AHP) dimana proses rekrutmen karyawan baru dengan metode AHP bertujuan untuk membantu manajer dalam pengambilan keputusan pada proses seleksi karyawan baru dengan menyajikan alternatif-alternatif yang ditampilkan dalam bentuk sistem perangkingan alternatif. Pada jurnal ini studi kasus dilakukan pada PT. Mitra Bisnis Seluler Kota Bukittinggi yang pada saat ini sedang melakukan proses rekrutmen karyawan baru. Untuk mempermudah manajer dalam pengambilan keputusan seleksi rekrutmen karyawan baru dengan metode AHP maka akan sehingga akan menghasilkan karyawan yang benar-benar berkualitas. Rekrutmen karyawan baru menggunakan 4 kriteria yaitu administrasi, pengetahuan, psikotest dan interview dengan CR= 0,01 yang menunjukan kriteria dapat diterima karena hasil yang ditunjukkan CR<10%. Analisa dilakukan terhadap 5 sampel kandidat karyawan baru yang menghasilkan perankingan dimana kandidat 3 memperoleh nilai tertinggi yaitu 0,28. Setelah proses pengujian dilakukan dengan aplikasi rekrutmen karyawan baru menggunakan metode AHP yang diterapkan pada 5 kandidat karyawan baru menunjukan bahwa sistem dapat dikategorikan dalam kondisi yang baik digunakan untuk pengambilan keputusan oleh manajer dalam proses seleksi karyawan baru.
IMPLEMENTASI ROUTING PROTOKOL BORDER GATEWAY PROTOCOL (BGP) PADA ROUTER MIKROTIK RB 2011 DI KOMINFO KABUPATEN SOLOK SELATAN
Authors: Putra Eko Kurniawanto 
Published: March 2022

Perkembangan teknologi digital saat pada saat ini sangat pesat, untuk mengiringi hal ini factor pendukung dari teknologi digital juga di harus kan dapat mendukung perkembangan ini faktor pendukung berupa instalasi jaringan komputer. Berbagai macam model penerapan jaringan komputer yang ada dapat di sesuai kan dengan kebutuhan dari pemakai layanan dipengaruhi dari proses route atau jalur penghubungnya antara sesama jaringan komputer. Seperti Kabupaten Solok Selatan yang sedang berbenah dengan semua kedinasan yang ada dapat tegabung dalam sebuah jaringan komputer yang dapat di kontrol terpusat. Untuk mengatasi masalah tersebut maka dibuatlah implementasi jaringan berskala MAN ( Metropolitan Area Netwok) pada Kabupaten Solok Selatan. Lokasi dari kedinasan yang ada di Kabupaten Solok Selatan sangat berpengaruh dalam implementasi jaringan ini. Model penentuan jalur (routing) sangatberpengaruh, untuk menghubungkan semua kedinasan adalah routing BGP (Border Gateway Protocol) yang mendukung untuk implementasi jaringan dalam skala besar. Kualitas Implementasi routing BGP dapat di jaga dengan pengujian QoS yang memaksimalkan teknologi digital yang ada di Kabupaten Solok Selatan. pengontrolan terpusat pada di dinas Komunikasi Dan Informatika (KOMINFO) membuat proses penerapan teknologi digital dan routing BGP membantu penanganan terhadap permasaalahn jaringan yang lebih mudah.
Magnetic Ranging Method for Horizontal Section Spacing Control of Cluster Wells
Authors: Diao Binbin , Gao Deli , Zhang Sen , Zhang Wenkai , Liu Zhe , Liu Rui 
Published: March 2022

Summary
Interwell fracture interactions are becoming an increasing problem with the large-scale exploitation of shale gas. High precision ranging technology is required for controlling the horizontal section spacing in cluster horizontal well drilling projects. The existing magnetic ranging technology has achieved remarkable application effects in the drilling engineering of twin horizontal wells, connected wells, and relief wells. But the maximum detection range cannot meet the needs of cluster horizontal well drilling engineering. A magnetic orientation sub connected to the nonmagnetic drill collar was designed to mark the position of the wellbore being drilled. Compared with the conventional magnetic sub connected to the drill bit, the magnetic orientation sub has a higher magnetic moment, is closer to the inclinometer, and has less effect on the build-up ability of the drilling tool. Although the effect of the magnetic orientation sub on the azimuth measurement is small when the azimuth angle is equal to 90° or 270°, the effect cannot be neglected in most cases. Therefore, we develop a computational model of the azimuth that considers the influence of the magnetic orientation sub. A new calculation model of distance and direction from the wellbore being drilled to the existing wellbore is developed to realize the ranging every 30 m or so. And the simulation experiment shows that the calculation accuracy of the distance and direction can meet the field needs of cluster horizontal well drilling engineering.
Inhibition mechanism of the chloride channel TMEM16A by the pore blocker 1PBC
Authors: Dutzler Raimund , Lam Andy , Rutz Sonja 
Published: March 2022

Abstract
TMEM16A, a calcium-activated chloride channel involved in multiple cellular processes, is a proposed target for diseases such as hypertension, asthma, and cystic fibrosis. Despite these therapeutic promises, its pharmacology remains poorly understood. Here, we present a cryo-EM structure of TMEM16A in complex with the channel blocker 1PBC and a detailed functional analysis of its inhibition mechanism. A pocket located external to the neck region of the hourglass-shaped pore is responsible for open-channel block by 1PBC and presumably also by its structural analogs. The binding of the blocker stabilizes an open-like conformation of the channel that involves a rearrangement of several pore helices. The expansion of the outer pore enhances blocker sensitivity and enables 1PBC to bind at a site within the transmembrane electric field. Our results define the mechanism of inhibition and gating and will facilitate the design of new, potent TMEM16A modulators.
Iatrogenic injury of the popliteal artery in orthopedic knee surgery - clinical results and development of a therapeutic algorithm
Authors: Goßlau Yvonne , Warm Tobias Dominik , Foerch Stefan , Zerwes Sebastian , Scheurig-Muenkler Christian , Hyhlik-Duerr Alexander 
Published: March 2022

Abstract
Purpose Intraoperative injury to the popliteal artery is a rare complication of orthopedic surgery, however, it can have serious consequences, including major amputation. Recommendations for a standard approach are lacking. The aim of this study was to develop an interdisciplinary therapeutic algorithm to assist in complication management. Methods From 01/11 to 12/20, 16 arterial injuries after knee surgery were analyzed in a retrospective single-center study. Four cases involved recurrent orthopedic surgery. Procedures performed included eleven total knee arthoplasties (TKA), two TKA replacements, one arthroscopy, and two high tibial osteotomies. Clinical presentation of patients was hemorrhage (n=2), ischemia (n=7), the combination of both (n=4), or pseudoaneurysm formation (n=3). Results Ten patients underwent endovascular treatment, some as combined procedures: (stent)-PTA (n=6), aspiration thrombectomy (n=5), thrombin injection (n=1), and embolization (n=1). Six patients were treated surgically: four with bypass/interposition and one with a patch plasty and one as a hybrid procedure, respectively. Only autologous great saphenous vein was used. All extremities could be preserved. Functional impairment remained in six cases. Conclusion Both endovascular and surgical procedures can be used to treat arterial injuries after knee surgery. Efficient standardized diagnosis and the involvement of vascular expertise are essential to prevent functional impairment or limb loss, as suggested in the algorithms.
Detection of Parvovirus B19 DNA in pregnant Sudanese women attending The Military hospital using Nested PCR technique
Authors: Abdelkabeer Tagwa Hafiz , Mohammed Nusaiba Elhadi , Khider Jala Suliman , Yassin Mustafa Eltigani , Idris Alkhair Abd Almahmoud 
Published: March 2022

Abstract
Background: Parvovirus B19 is a human pathogenic virus associated with a wide range of clinical conditions. During pregnancy congenital infection with parvovirus B19 can be associated with poor outcome, including miscarriage, fetal anemia and non-immune hydrops. Objective: The study aimed to determine the prevalenceof Parvovirus B19 DNA in pregnant women attending the Military hospital in Khartoum, demonstrating the association between the virus and poor pregnancy outcomes. Materials and methods: This study was a cross sectional study, testing pregnant Sudanese women whole blood samples (n= 97) for the presence of Parvovirus B19 DNA using nested PCR technique. Result: Two samples were found positive for Parvovirus B19 DNA out of the total number of samples screened. Conclusions: The prevalence of Parvovirus B19 DNA among pregnant women attending the Military hospital was 2.1%.
Soil algae for combating soil degradation - greenhouse experiment with different soil amendments
Authors: Zhang Xin , Koehler Hartmut 
Published: March 2022

Abstract
Our research contributes to the knowledge of using soil algae to combat soil degradation. We tested green algae (Klebsormidium flaccidum) and a field community in a three-month greenhouse experiment and studied their performance on two substrates: sand from the Ordos Desert and artificial desert soil (washed sand). Also a rapid fluorescence microscopy-Image J method was developed to assess the abundance of algae. We studied the effects of four soil amendments (biochar, clay, organic matter, geohumus®) on the development of green algae, field algae and biological soil crusts. K. flaccidum developed better than field communities, and field algae preferred washed sand. All amendments had a positive effect on the abundance of K. flaccidum and field algae. Biological soil crusts were generally lower in control and organic matter treatments, but relatively higher in biochar and clay treatments. No relationship between algal abundance and soil crust stability was found in this short-term experiment.
The Impact of Government Actions and Risk Perception on the Promotion of Self-Protective Behaviors During the COVID-19 Pandemic
Authors: Alvarez-Galvez Javier , Anastasiou Andreas , Lamnisos Demetris , Constantinou Marios , Nicolaou Christiana , Papacostas Savvas , Vasiliou Vasilis S. , McHugh Louise , Lubenko Jelena , Ruiz Francisco J. , Paez-Blarrina Marisa , Montesinos Francisco , Valdivia-Salas Sonsoles , Merwin Rhonda M. , Karekla Maria , Gloster Andrew T. , Kassianos Angelos P. 
Published: March 2022

Abstract
We aim to understand the factors that drive citizens of different countries adhere to recommended self-protective behaviors during the COVID-19 pandemic. Survey data obtained through the COVID Impact project was used. We combined previous evidence and change-point detection analysis to establish variations in self-protective behaviors across participating countries whose effect was then assessed by means of interrupted series analysis. A high level of compliance with health and governmental authorities’ recommendations were generally observed in all countries. The level of stress decreased near the period when countries such as Cyprus, Greece or the United Kingdom relaxed their prevention behavior recommendations. However, this relaxation of behaviors did not occur in countries such as Germany, Ireland or the United States. When the daily number of recorded COVID-19 cases decreased, people relaxed their protective behaviors (Cyprus, Greece, Ireland), although the opposite trend was observed in Switzerland. COVID-19 self-protective behavior following has been heterogeneous across countries examined. Our findings show that there is probably no single winning strategy for exiting future health crises, as similar interventions, aimed to promote self-protective behaviors, may be received differently depending on the singular population groups and on the specific geographical context in which they are implemented.
Determination of Total Phenolic Content and Antioxidant Activity of Commiphora mollis (Oliv.) Engl. Resin
Authors: Molole Guyo Jilo , Gure Abera , Abdissa Negera 
Published: March 2022

Abstract
In this study, total phenolic contents (TPC) and antioxidant activity of Commiphora mollis (Oliv.) Engl. (Burseraceae) resin was investigated. The resin was extracted using petroleum ether, chloroform, and methanol and yielded 27.46 ± 0.48, 46.56 ± 0.42, and 53.00 ± 1.39% extractable solids, respectively. The Folin-Ciocalteu redox (F-CR) assay was optimized considering relevant parameters such as reaction time, maximum wavelength, and dilution effect before the determination of TPC. The amount of antioxidant necessary to decrease by 50%, the initial concentration of DPPH (EC50) was determined at 60 min. The kinetics of the reaction was analyzed taking into account the pseudo-first-order model. For the F-CR assay, the optimum conditions for the maximum absorbance and analysis time were 760 nm and 30 min, respectively. Under these conditions, the method was valid and the instrumental response was linear and sensitive. Relatively, higher TPC was obtained in diluted samples (500 µg/mL): 168.27 ± 3.44, 137.43 ± 1.32, and 136.16 ± 0.42 mgGAE/g from methanol, chloroform, and petroleum ether extracts, respectively. By using different concentrations of the test sample, exhaustive reduction of phenolics and/or antioxidant substrates was achieved. The obtained DPPH radical scavenging capacity index (EC50) was 44.72 ±0.48 for ascorbic acid, and 295.03 ± 3.55, 342.75 ±9.72 and 353.69 ± 7.30 µg/mL for methanol, chloroform, and petroleum ether extracts, respectively. The methanol extracts showed better kinetic behavior (k2 values: 115.08 to 53.28 M-1s-1 and steady-state time < 30 min), which was closer to the standard L-ascorbic acid (k2 values; 190 to 109 M-1s-1), than other extracts. Results of the current study showed that polar solvent, methanol resulted in better F-CR reducing capacity and DPPH radical scavenging activity than nonpolar solvents which displayed similar effects (p > 0.05). This could have resulted from different antioxidants extracted from C. mollis resin. In conclusion, C. mollis resin could be a useful source of antioxidants. For better understanding, further study accompanied by isolation of pure compounds is recommended.
Cost-Effectiveness Analysis Of Pegfilgrastim In Patients With Non-Small Cell Lung Cancer Receiving Ramucirumab Plus Docetaxel In Japan
Authors: Kondo Yu , Tachi Tomoya , Sakakibara Takayoshi , Kato Jun , Kato Aki , Mizuno Takahito , Miyake Yoshio , Teramachi Hitomi 
Published: March 2022

Abstract
Purpose: The dose-limiting factor of ramucirumab plus docetaxel (RAM+DTX) therapy in patients with non-small cell lung cancer (NSCLC) is febrile neutropenia (FN), which has a higher incidence in Asians. Pegfilgrastim (Peg-G) is routinely used for FN prophylaxis in Japan. This study aimed to evaluate the cost-effectiveness of Peg-G in patients with NSCLC receiving RAM+DTX in Japan.Methods: We simulated model patients treated with RAM+DTX in Japan and developed a decision-analytical model for patients receiving Peg-G prophylaxis or no primary prophylaxis. The expected cost, quality-adjusted life-year (QALY), and incremental cost-effectiveness ratio (ICER) of each treatment were calculated from the perspective of a Japanese healthcare payer. The willingness-to-pay (WTP) threshold was set at 45,867 United States dollars (USD) (5 million Japanese yen) per QALY gained. The probabilities, utility values, and other costs were obtained from published sources. Deterministic sensitivity analysis (DSA) and probabilistic sensitivity analysis (PSA) were conducted to evaluate the effect of each parameter on the results and robustness of the base-case results.Results: The expected cost and QALYs gained were 4,394 USD and 0.603 for Peg-G prophylaxis, and 2,242 USD and 0.578 for no primary prophylaxis, respectively. The ICER was calculated to be 83,147 USD per QALY gained. The results of DSA were most sensitive to FN risk with Peg-G. PSA revealed a 23.7% probability that primary prophylaxis with Peg-G was cost-effective. Conclusion: Peg-G is not cost-effective in patients with NSCLC receiving RAM+DTX in Japan.
Chemotherapy, Immunotherapy, and Surgery Should be Optimal Treatment Choices of Metastatic Sarcomatoid Renal Cell Carcinoma
Authors: Chen Yongmei , Lu Dongming , Yin Zhenjie , Zhou Weiwen , Bai Yuanyuan , You Bingyong , Chen Daoxun , Liao Shangfan , Wu Zongqiang , Zhang Fabiao , Wang Ying , Lin Tingting , Sun Yingming , Wu Yongyang 
Published: March 2022

Abstract
Background: Sarcomatoid renal cell carcinoma (sRCC) is aggressive and with a poor prognosis. The therapeutic strategy of sRCC is unclear. We aim to evaluate the effectiveness of chemotherapy on sRCC and investigate the potential remedy to fight the sRCC. Methods: Patient information was derived from US Surveillance, Epidemiology, and End Results (SEER) database, and the demographic and clinical characteristics as variables were adopted. We apply log-rank to generate Kaplan–Meier survival curve. We established a nomogram by Cox proportional hazard model and apply the concordance index (C-index) and receiver-operating characteristic (ROC) to verify the quality of the model. Results: 809 patients were collected from SEER database. There are six independent prognostic factors, including age, sex, T stage, N stage, surgery, chemotherapy, that were employed to establish a prognostic model. The C-index of the model was 0.696. Tissue microarray (TMA) results suggested that programmed cell death ligand 1(PD-L1) was highly expressed in sRCC patients. Conclusions: Patients who have metastatic disease in sRCC can benefit from chemotherapy and surgery. Immunotherapy is promising to treat sRCC and should lunch a clinical trial at the current stage.
Evaluation of The Landslide Processes In Cayambe, Pichincha, Ecuador
Authors: Flores Graciela , Strokova Lyudmila A. , Varela-Aldás José 
Published: March 2022

Abstract
The present work proposes the use of the statistical method of frequency ratio (RF) and the hierarchical analytical process (AHP) to obtain zoning maps of the landslide processes, determining the susceptible areas in the territory of the Cayambe canton located in the province of Pichincha in Ecuador. Statistical methods use sample data based on the relationship between landslides and causal factors, evaluating the combination of these data objectively. As results, it was identified that the analysis of the landslide indices according to the FR method and the AHP method, shows that the inclination of the slope and the exposure are the important factors in the analysis of the susceptibility of the territory. However, a separate analysis shows that, for the FR method, the stratigraphic genetic complex factor is the most relevant, while for the AHP method, the most important factor is the steepness of the slope. On the other hand, the analysis of the distribution of landslides by parish shows that rural parishes present a greater number of landslide processes. In this way, it is highlighted that the Cangahua rural parish has 42% of the total landslides identified in the canton. Followed by the parishes Santa Rosa de Cusubamba and San José de Ayora, together with 29% of the landslides.
Prevalence, Associated Risk Factors and Molecular Characterization of Eimeria Species Affecting Backyard Poultry of Jammu Region, North India
Authors: Khursheed Aiman , Yadav Anish , Sofi Omer Mohi-U-Din , Kushwaha Anand , Yadav Vikas , Rafiqi Shafiya I. , Godara Rajesh , Katoch Rajesh 
Published: March 2022

Abstract
The present study was conducted from January 2018 to December 2019 to know the prevalence of coccidiosis in backyard poultry in Jammu, Samba and Udhampur districts of Union Territory of Jammu and Kashmir, North India. A total of 600 pooled faecal samples collected from backyard poultry were examined for presence of Eimeria oocysts. Morphometry and Polymerase Chain Reaction (PCR) based amplification of ITS-1 gene was carried to characterize the Eimeria species infecting the backyard poultry of the study area. An overall prevalence of 28.5% Eimeria spp. infection among backyard poultry birds was recorded. Among the seasons, highest prevalence was recorded during rainy season (32%) with significantly (p<0.05) high oocyst excretion (1.77±0.01) and lowest during summer (19.3%) with low oocyst excretion (0.17±0.006). Young birds upto 3 months of age were found to be more susceptible to infection than older birds, with a significantly (p<0.05) high prevalence percentage of 38.02. Morphometry with COCCIMORPH software revealed presence of Eimeria acervulina, Eimeria maxima, Eimeria necatrix, and Eimeria tenella species with prevalence rates of 16.5%, 3.6%, 21.3%, and 27.6%, respectively.The amplified fragments of ITS-1 gene presented different sizes of Eimeria spp. viz. E. acervulina (321bp), E. tenella (278 bp), E. maxima (145 bp) and E. necatrix (383bp). The study concluded that although backyard poultry didn’t show clinical form of coccidiosis but may act as source of potential reservoir.
Strength, durability, and microstructure of self-compacting geopolymer concrete produced with copper slag aggregates
Authors: Arora Saloni , Jangra Parveen , Lim Yee , Pham Thong 
Published: March 2022

Abstract
Lack of vibrations on fresh concrete negatively influences the compaction and thus the quality of concrete. This is particularly concerning with geopolymer concrete (GPC) containing sodium silicate (Na 2 SiO 3 ), which is viscous in nature. In this study, self-compacting geopolymer concrete (SCGC) containing fly ash (FA) and ultrafine slag (UFS) with copper slag aggregates (CSA) was proposed and investigated. CSA were used as a substitute to sand (by weight) in SCGC at different percentages up to 60%. In the fresh state, slump, T500 slump flow, V-funnel, L-box, U-box, and sieve aggregation ratio tests were performed to investigate flowability, passing ability, and viscosity. At the hardened state, the compressive strength, water absorption, chloride ion resistance and sorptivity tests were examined. The flowability of SCGC improved when CSA were added, and the highest slump of 735 mm was achieved for the mix with 60% CSA. Substitution of up to 20% of CSA enhanced the properties of SCGC at all ages. Mix having 20% CSA (20CSA-SCGC) was superior to other mixes, exhibiting the highest compressive strength (47 MPa) at 365 days while possessing the lowest water absorption, sorptivity, and the highest chloride ion resistance. Scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) analyses also confirmed the improved microstructure of Mix 20CSA-SCGC. Meanwhile, X-ray diffraction (XRD) analysis confirmed the presence of quartz and calcium silicate hydrate (CSH) products, which were the main contributors to properties enhancement.