bluuebunny/crossref_metadata_2025_split huggingface dataset:
COVID-19 and the Infodemic: An Overview of the Role and Impact of Social Media, the Evolution of Medical Knowledge, and Emerging Problems
Authors: Corinti Francesca , Pontillo Daniela , Giansanti Daniele 
Published: April 2022

The infodemic is an important component of the cyber-risk in regard to the poor and uncontrolled dissemination of information related to the COVID-19 pandemic. The purpose of this study was to perform a narrative review based on three points of view to allow for an overall picture of this issue. The points of view focused on: (a) the volume of use of social media (a key element of the infodemic) and the position of international health domain bodies; (b) the evolution of scientific production in the life sciences; (c) emerging issues. The research methodology was based on Google and PubMed searches and a qualification process based on a standard checklist and an evaluation of eligibility based on parameters with five score levels applied by two experts (plus one in case of discrepancy). The three points of view stressed the key role of social media as a dissemination tool of the infodemic among citizens. The impact on citizens depends on various social factors and involves indirect (e.g., vaccine avoidance) and direct risks such as mental problems and the risk of suicide. The widespread diffusion of social media, conveyed by mobile technologies, also suggests their use as countermeasures, calibrated based on citizens’ level of both technological and health literacy. Effective and promising countermeasures in this direction are based both on initiatives of contact by apps or SMS and the collection of data based on surveys and finalized to the particular intervention. The review also suggests as further areas of in-depth research: (a) to combat high-level infodemic produced by scientific publications that are not yet official (preprint) or that have undergone peer review with bias/distortion; (b) focusing on the impact of the infodemic considering its spread in different languages.
Identification of virulence resistance genes in Pseudomonas aeruginosa strains isolated from blood samples
Authors: BIYIK İlknur , TANRIVERDİ ÇAYCI Yeliz , ATIGAN Ege Berke , BIRINCI Asuman 
Published: April 2022

Aim: In this it is aimed to the determine the presence of virulence resistance genes (toxA, algD, plcN, lasB, plcH) in P. aeruginosa isolates isolated from blood samples.
Materials and methods: DNA extraction of the study isolates was done by boiling method. Optimization was done using positive control after DNA extraction. After optimization, the presence of virulence (toxA, algD, plcN, lasB, plcH) resistance genes was investigated by polymerase chain reaction (PCR) method.
Results: As a result of PCR of the virulence gene regions (toxA, algD, lasB, plcN, plcH); Positive rates of KR 25 isolates were 80% (n=20), 100% (n=25), 100% (n=25), 100% (n=25), 96% (n=24) in KS 46 isolates. On the other hand, the positive rate distributions were found to be 93.47% (n=43), 100% (n=46), 100% (n=46), 100% (n=46), 97.82% (n=45).
Conclusion: As a result of PCR of virulence gene regions (toxA, algD, lasB, plcN, plcH) of P. aeruginosa, it was determined that algD, lasB, plcN genes were found in all 25 carbapenem resistant (KR) and 46 carbapenem sensitive (KS) isolates.
Infective Endocarditis in the Current Clinical Practice
Authors: Горбич Ю.Л. , Карпов И.А. , Соловей Н.В. , Горбич О.А. 
Published: April 2022

Инфекционный эндокардит остается заболеванием с относительно высокой летальностью, достигающей в настоящее время 1520 среди установленных случаев. Летальность в большинстве случаев связана с отсутствием или поздней диагностикой заболевания. В статье освещены ключевые аспекты этиологии, возможности диагностики (в том числе ранней диагностики) инфекционного эндокардита. Клиническая картина заболевания крайне неспецифична и не позволяет установить этот диагноз. Модифицированные критерии Дьюка и эхокардиография остаются основой диагностики, однако новые методики визуализационной диагностики (позитронно-эмиссионная томография, многослойная компьютерная томография с ангиографией) расширяют возможности постановки диагноза в сложных случаях. Особое внимание уделено вопросам антимикробной терапии инфекционного эндокардита, приведены схемы эмпирической и этиотропной терапии у пациентов с естественными и протезированными клапанами, факторы риска грибкового эндокардита и практические особенности использования наиболее широко применяющихся антибиотиков. Обсуждены возможности профилактики инфекционного эндокардита, которая в настоящее время рекомендована для применения только при ряде инвазивных стоматологических вмешательств у пациентов высокого риска.
Infective endocarditis (IE) remains a highly mortal disease with approximately 1520 of lethal outcomes among established cases. In the vast majority of cases mortality in IE patients is associated with missed or made only late in the disease course diagnosis. Key features of the infective endocarditis etiology and diagnostics (incl. early diagnostics) are highlighted in this article. Clinical picture of the disease is nonspecific and does not allow making a diagnosis. The modified Duke Criteria and echocardiography remain the cornerstones of the diagnosis, however the new imaging methods (positron-emission tomography, multislice computed tomography with angiography) enlarge diagnostic options in complex and tricky cases. Particular attention was paid for antimicrobial therapy of infective endocarditis. Recommendations for empiric and targeted therapy in patients with native and prosthetic valves, risk factors for fungal endocarditis and practical essentials for the most widely used antibiotics are included in the article. Prophylactic approaches for infective endocarditis are also discussed. Issued guidelines recommend antibiotic prophylaxis only in high-risk patients before selected invasive dentistry procedures.
Metode Runge-Kutta Orde 4 Dalam Penyelesaian Persamaan Gelombang 1D Syarat Batas Dirichlet
Authors: Enkekes Yenci Brika , Mardianto Lutfi 
Published: April 2022

The problem studied in this study was the movement of deviations in the equation of 1D waves on the rope given the initial deviation value. In this study, the equation of 1D waves with dirichlet boundary problems will be solved analytically using variable and numerical separation using the runge-kutta method approach of order 4. This research begins with examining equation models, solving analytical solutions, applying schemes to the final results of simulations. The decrease in equation model fissile is done by reviewing the working force on a piece of rope, solving an analytical solution with a variable separation method, and numerical completion resulting in the best simulation result with parameter c= 0.5 with time steps ∆x= 0.01 and time interval of 0 ≤ t≤ 1 resulting in a numerical approach close to its analytical solution up to t= 1 s and the influence of parameter c on the movement of wave deviations resulted in that the influence of parameter c affects the magnitude of the deviation of the wave, so the greater the value of parameter c, the smaller deviation of the wave and the faster the speed of the direction. Thus, it can be concluded that the runge-kutta method of order 4 in this study can be said to be one of the numerical approaches of the problem of 1D wave equations with dirichlet boundaries.
BLUE ECONOMY DEVELOPMENT IN INDONESIA
Authors: Razladova Oksana , Nyoko Antonio E. L. 
Published: April 2022

This work is highlighting the possibilities to enhance blue economy development in Indonesia with environmentally friendly and sustainable solutions to assure successful future and growth. Literatures review and Focus Group Discussion were conducted to collect Indonesia profiles and potential factors to be developed in blue economic strategic planning. Blue economy employment opportunities would enhance gender balance also due to specialization job offers where females proved to be potentially more productive than males. Marine Spatial Planning (MSP) originates from nature conservation approach in the Great Barrier Reef. MSP has gain since then a lot of attention due to overused of marine areas. Ecosystem based approach for MSP could result in clean, healthy, safe, productive, and diverse ocean. It could influence where and when the human activities could occur. MSP normally require authority to plan the one and another to implement. Funding normally has government based but could be supported with grants, partnerships, and private sector funding. All activities have to be monitored to assure progress of achievements and environmental effect.
Keywords: Blue Economy Development, Indonesia, Gresik, Marine Spatial Planning
SELECTION OF PERFORATED PIPE DIAMETER OF SEED PLACEMENT DEVICE IN THE SOIL
Authors: Николаев В.А. , Кряклина И.В. 
Published: April 2022

Для создания оптимальных условий прорастания семян и развития растений необходимо обеспечить им оптимальную площадь питания. Она представляет квадрат со сторонами приблизительно 40 х 40 мм. Предложен комбинированный агрегат обработки почвы и посева, обеспечивающий оптимальное размещение семян в почве. В состав агрегата входит устройство размещения семян в почве. Важным элементом устройства размещения семян является перфорированная труба. В результате расчётов и пространственного моделирования выявлены зависимости: количества драже между первым и вторым сбрасывателем от наружного диаметра перфорированной трубы; максимального количества отверстий от наружного диаметра перфорированной трубы, исходя из геометрии перфорированной трубы и исходя из возможного количества драже между первым и вторым сбрасывателем. На основании проведённых исследований определён оптимальный наружный диаметр, количество отверстий в поперечном сечении перфорированной трубы и угол между осями этих отверстий.
To create optimal conditions for seed germination and plant development, it is necessary to provide them with an optimal feeding area. It represents a square with sides of approximately 40 x 40 mm. A combined unit for tillage and sowing is proposed which ensures optimal placement of seeds in the soil. The unit includes a device for placing seeds in the soil. An important element of the seed placement device is a perforated pipe. As a result of calculations and spatial modeling, the following dependencies were revealed: the number of dragees between the first and second ejector from the outside diameter of the perforated pipe, maximum number of holes from the outside diameter of the perforated pipe, based on the geometry of the perforated pipe and based on the possible number of dragges between the first and second ejector. Based on the researches conducted the optimal outside diameter, the number of holes in the cross section of the perforated pipe and the angle between the axes of these holes were determined.
Raman fl uorescence technologies for early detection of infl ammatory and oncological disorders as a part of public health strategy and a tool for improving the quality of medical care: a review
Authors: Timurzieva A. B. 
Published: April 2022

The increasing morbidity and mortality rate in inflammatory and oncological diseases requires determining the public health strategies for early detection of such disorders and improving the quality of medical care. For this goal, high-tech modalities with high sensitivity, specificity and accuracy are to be worked out. Rаman fluorescent medical technologies (RFMT) can be successfully applied in the diagnostics of inflammatory and tumor diseases if to develop a specific algorithm for express analysis of histological, physiological, microbiological and other components of biological tissues. The given article presents a brief overview on the application of Raman fluorescence spectrometry in the diagnostics of diseases. This medical technology, which utilizes the phenomenon of tissue autoflorescence and Raman light scattering, is a promising tool for early diagnostics of different inflammatory and oncological pathologies. The described nоn-invasive method allows to make an express assessment of metabolic, morphometric and functional tissue parameters in intact and in pathological tissue. The present discussion is aimed to find out points for the application of Rаman fluorescence spectrometry and its various modifications; to assess its potentials for screening; to develop a specific algorithm for the diagnostics of inflammatory and tumor pathologies. RFMT is a promising modality for future applications so as to improve the quality of medical care by early detection of inflammatory and tumor diseases and early prescription of rational therapy.
Influence Oxytocin Massage on Reduce Lactation Problems and Support Infants Growth
Authors: Lestari Prasetya , Fatimah Fatimah , Ayuningrum Lia , Herawati Herni Dwi , Afifaturrohmah Nisrina 
Published: April 2022

Background: Lactation problems often occur in the early postnatal period. One of them is the readiness of the mother in early breastfeeding. Early breastfeeding is one of the effective efforts in providing nutrition for newborns and preventing lactation problems. In 2019, in Indonesia, the percentage of newborns who received early breastfeeding was 75.58%. The success rate of this is closely related to lactation readiness in early postpartum. To support the success of lactation, postpartum mothers need to be given education on methods to stimulate milk production at the beginning of the puerperium with oxytocin massage. Good breast milk production will support the nutritional adequacy of the baby and reduce lactation problems in the early postpartum period. Objectives: the purpose of this study was to determine the effectiveness of oxytocin massage on lactation problems and infant growth. Methods: This study was pre-experimental research using posttest only design and true-experiment using posttest only control group design. The research locations were in the Mother and Child Health Clinic and Midwives Independent Practice (PMB) in Bantul, Sleman, and Gunung Kidul Yogyakarta. Implementation from April until September 2020. The population of this study was all the families of postpartum mothers from the first to the third day and after 1 week an evaluation of breastfeeding. The sampling technique uses total sampling was 80 postpartum mothers on the first-third day of childbirth until the baby was 2 months old. The research instruments were the oxytocin massage checklist, lactation problems, and body length observation sheet. Test analysis using Wilcoxon. Results: The results of this study were that the majority of respondents performed oxytocin massage with a frequency more than 3 times (51%) the first week of postnatal, respondents experienced lactation problems in the first week of postnatal by 16.3% and at the 4th postnatal visit all respondents had no lactation problems. The average increase in the length of the baby's body at the age of 2 months is 8.44. The majority of the baby's body length at the age of 2 months corresponds to age (98.8%). The results of bivariate analysis of oxytocin massage were effective in reducing lactation problems (p=0.000) and supporting infants' growth (p=0.000). Conclusion: Oxytocin massage is effective in reducing lactation problems and supporting infants' growth. Oxytocin massage should be implemented in postnatal care to prevent lactation problems and support breastfeeding.
Effectiveness of 6-month Use of Secukinumab in Patients With Psoriatic Arthritis in the CorEvitas Psoriatic Arthritis/Spondyloarthritis Registry
Authors: Mease Philip J. , Blachley Taylor , Dube Blessing , McLean Robert R. , Kim Nina , Hur Peter , Ogdie Alexis 
Published: April 2022

Objective.To evaluate clinical and patient-reported outcomes (PROs) at 6 months after secukinumab initiation in US patients with psoriatic arthritis (PsA).Methods.Patients with PsA in the CorEvitas Psoriatic Arthritis/Spondyloarthritis Registry who initiated secukinumab between April 1, 2017, and December 2, 2019, and maintained secukinumab at their 6-month follow-up visit were included. Achievement of minimal disease activity (MDA) among patients not in MDA at initiation; resolution (ie, no evidence) of tender and swollen joint counts, enthesitis, and dactylitis among patients with ≥ 1 of these at initiation; and change in disease activity and PROs were evaluated at 6 months in all patients and in patients who received secukinumab as a first-line biologic.Results.Of the 100 eligible patients included, most (83.0%) were biologic experienced and 17.0% initiated secukinumab as a first-line biologic. At initiation, 75/90 patients (83.3%) with available data were not in MDA; 26/71 (36.6%) with follow-up data achieved MDA at 6 months. Further, 28/68 patients (41.2%) with ≥ 1 tender joint, 24/54 (44.4%) with ≥ 1 swollen joint, 17/28 (60.7%) with enthesitis, and 9/12 (75.0%) with dactylitis at initiation achieved resolution at 6 months. Improvements in clinical manifestations, PRO measures, and work productivity and activity were observed after 6 months among patients with PsA who initiated and maintained secukinumab.Conclusion.In this real-world population, patients with PsA who received and maintained secukinumab for 6 months achieved MDA in proportions consistent with clinical trials and demonstrated improvements in clinical manifestations and PROs.
Monitoring of Disease Activity With a Smartphone App in Routine Clinical Care in Patients With Axial Spondyloarthritis
Authors: Kempin Robin , Richter Jutta G. , Schlegel Anna , Baraliakos Xenofon , Tsiami Styliani , Buehring Bjoern , Kiefer David , Braun Juergen , Kiltz Uta 
Published: April 2022

ObjectiveTo investigate the performance of a health app with respect to usability, adherence, and equivalence of data in daily care of patients with axial spondyloarthritis (axSpA).MethodsConsecutive patients with axSpA were asked to export patient-reported outcomes (PRO) electronically with the AxSpA Live App regularly every 2 weeks over a period of 6 months. The first clinical visit was followed by 2 further personal visits after 3 and 6 months. Patients completed paper-based PRO at every visit; they also completed the Mobile App Rating Scale and the System Usability Scale after 3 and 6 months.ResultsOf 103 patients with axSpA, 69 agreed to participate (67.0%): age 41.5 (11.3) years, 58.0% male, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) 4.3 (2.0), and 76.8% treated with biologic disease-modifying antirheumatic drugs. Patients’ adherence to regular app exports was 29.0% and 28.4% after 3 and 6 months, respectively. Significant predictors for good adherence were high disease activity (P = 0.02) and older age (P = 0.04). No systematic differences between digital and paper-based BASDAI scores were found (intraclass correlation coefficients 0.99 [95% CI 0.98-0.99]). Performance of the app was rated as good.ConclusionCollection of digital PROs by AxSpA Live App may be successfully used in patients with axSpA with high disease activity. Our study showed equivalence of digital data, but adherence to the app after 6 months was poor. Higher disease activity and older age resulted in increased adherence to the app. This suggests that the use of health apps like this should concentrate on more severely affected patients.
Resserrer les liens : approche systémique et désinstitutionalisation
Authors: Soria Delphine 
Published: April 2022

Cet article aborde une des manières possibles de construire le travail avec les familles au sein d’une institution accueillant des adolescents. Dans le processus actuel de désinstitutionalisation, l’approche systémique peut-elle être un recours, tant pour les usagers que pour les professionnels ?
Soigner nos liens pour soigner le lien : Du lion au singe en passant par la licorne…
Authors: Kaisin Patrick , Ameye Sarah , Boucau Valérie , Lallemand Bernadette , Noël Camille , Pirlot Vanessa , Van Ypersele David , Lempereur Emmanuelle 
Published: April 2022

Les dernières années ont vu se multiplier le recours au terme « incasable » pour qualifier une certaine catégorie de jeunes qui épuisent les institutions et sont ballotés de l’une à l’autre. À partir d’une présentation du parcours de vie et de l’hospitalisation d’une jeune fille de 10 ans présentant un attachement insécure désorganisé et des symptômes de dissociation post-traumatique, l’article explore les éléments qui ont soutenu sa prise en charge. Parmi ceux-ci, l’accent est particulièrement mis sur l’importance de diffracter les liens et les relations transférentielles, à la fois dans l’unité de soin, dans l’institution de soin et entre celles-ci et les partenaires du réseau de la jeune. Le rôle et l’utilisation de certains objets ainsi qu’un modèle de prise en charge en co-thérapie par une psychologue et une kinésithérapeute sont proposés. Enfin, l’article présente le témoignage de la jeune recueilli sous la forme d’un jeu de sable.
Nous ne savons pas et c’est notre chance !
Authors: Verbist Yolande , Pietquin Thomas 
Published: April 2022

Parmi toutes les institutions qui prennent en charge l’enfance, il y a l’école. L’école, on ne la choisit pas toujours, et plus on a de difficultés, moins on choisit. À l’école, adultes et enfants sont confrontés à leur non-savoir et à leur impuissance. Ce non- savoir est une chance : il oblige à la rencontre ! C’est elle qui peut ouvrir à ce mouvement qu’est l’apprentissage. Dans les situations où plusieurs services et familles sont « condamnés » à travailler ensemble et à s’accorder, il s’agit de « tenir ensemble le cadre » pour bricoler un collectif sécurisé et sécurisant afin qu’apprendre soit enfin possible !
Relations de services
Authors: Livian Yves-Frédéric 
Published: April 2022

Résumé Parmi les principaux aspects de la relation de service, il convient d’avoir à l’esprit : la pression sur les résultats, la tendance à la normalisation, l’évolution sociétale de certains comportements, le rôle essentiel de l’engagement subjectif… Plusieurs tensions apparaissent dans l’exercice de la relation de service : des prestations homogènes versus individualisation des services, le respect des procédures versus la personnalisation de la prestation, l’autonomie versus le contrôle des salariés… Sur le plan des pratiques de gestion inadaptées, à retenir : l’inadaptation des outils informatiques lors de l’interaction attendue avec le client, l’absence d’influence du département GRH sur l’organisation du travail, le contenu des tâches, les risques psychosociaux. Au regard des pistes d’action possibles, l’accent est mis sur les démarches participatives de conception des postes de travail ou des outils, la formation de la hiérarchie intermédiaire, l’intérêt à s’appuyer sur un examen de l’activité réelle des salariés, de disposer d’espaces d’échanges et de réflexion sur les pratiques.
Arab American Identity in Mohja Kahf’s The Girl in the Tangerine Scarf
Authors: Bayeh Jumana 
Published: April 2022

Dans cet article nous nous demandons comment l’identité se forme, comment elle se négocie et comment elle se transforme dans un contexte de diaspora et de migration. Ce questionnement prend place dans la fiction arabo-américaine de l’Amérique post-11 Septembre. Prenant pour objet d’analyse le roman The Girl in the Tangerine Scarf de Mohja Kahf, nous cherchons à souligner le rôle essentiel que joue le récit et la mise en récit pour comprendre comment l’identité est influencée et altérée dans un monde où le racisme et les discriminations contre les Arabes et les Musulmans se sont intensifiés.
Photography and the Remapping of Home in Contemporary Arab American Literature
Authors: Arami Sara 
Published: April 2022

Cet article a pour but d’étudier les notions de « chez soi » et d’identité dans la fiction de deux auteures arabo-américaines à travers l’utilisation de représentations photographiques et de photos. Il se concentre sur la manière dont la photographie et les photos sont mises en œuvre dans les récits de deux romans de Mohja Kahf et Alia Yunis afin d’examiner comment les personnages immigrés des romans s’engagent dans un processus de reconfiguration de l’espace du « chez soi ».