bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associations between coastal proximity and children’s mental health in Australia
Authors: Oostenbach Laura H. , Noall Jennifer , Lamb Karen E. , Pearson Amber L. , Mavoa Suzanne , Thornton Lukar E. 
Published: November 2022

AbstractLimited research has explored associations between blue spaces and mental health, specifically in children. This study assessed links between coastal proximity and depression and anxiety among children in Australia and tested whether duration of residency at current address moderated associations. It also explored associations between within‐individual changes in coastal proximity and changes in depression and anxiety. Data were from 2400 children aged 11–12 years in Wave 5 (2012) and aged 14–15 years in Wave 6 (2014) of the national Longitudinal Study of Australian Children. Outcomes were children’s self‐reported symptoms of depression and anxiety. Exposure was coastal proximity (<2, 2–<5, 5–<10, 10–<20, 20–<50, and ≥50 km). Linear models were fitted to examine cross‐sectional associations and fixed effects models for within‐individual associations. After adjustment for potential confounders, findings suggested that those living close to the coast (<2 km) had lower levels of depression than those living the furthest from the coast (≥50 km) during childhood (Wave 5) but not adolescence (Wave 6). No associations were observed with anxiety. There was weak evidence to suggest residency duration moderated associations. No associations were observed for within‐individual changes. Further research is needed to understand whether and what characteristics of coastal environments may benefit children’s mental health.
Development and characterization of probiotic (co)encapsulates in biopolymeric matrices and evaluation of survival in a millet yogurt formulation
Authors: Kouamé Kouadio Jean Eric‐Parfait , Bora Awa Fanny Massounga , Li Xiaodong , Sun Yue , Tian Songfan , Hussain Muhammad , Liu Lu , Coulibaly Ibourahema 
Published: November 2022

AbstractThe formulation of probiotics‐enriched products still remains a challenge for the food industry due to the loss of viability, mainly occurring upon consumption and during storage. To tackle this challenge, the current study investigated the potential of using sodium alginate and inulin (SIN) in combination with various encapsulating materials such as skim milk (SKIM), whey protein concentrate (WPC), soy protein concentrate (SPC), and flaxseed oil (FS) to increase the viability of Lactobacillus casei upon freeze‐drying, under simulated gastrointestinal conditions, during 28 days of storage at 4°C, and in a formulation of millet yogurt. Microstructural properties of microcapsules and co‐microcapsules by SEM, oxidative stability of flaxseed oil in co‐microcapsules, and physicochemical and sensory analysis of the product were performed. The produced microcapsules (SIN‐PRO‐SKIM, SIN‐PRO‐WP, and SIN‐PRO‐SP) and co‐microcapsules (SIN‐PRO‐FS‐SKIM, SIN‐PRO‐FS‐WP, and SIN‐PRO‐FS‐SP) had a high encapsulation rate >90%. Moreover, encapsulated and co‐encapsulated strains exhibited a high in vitro viability accounting for 9.24 log10 CFU/g (SIN‐PRO‐SKIM), 8.96 log10 CFU/g (SIN‐PRO‐WP), and 8.74 log10 CFU/g (SIN‐PRO‐SP) for encapsulated and 10.08 log10 CFU/g (SIN‐PRO‐FS‐SKIM), 10.03 log10 CFU/g (SIN‐PRO‐FS‐WP), and 10.14 log10 CFU/g (SIN‐PRO‐FS‐SP) for co‐encapsulated. Moreover, encapsulated and co‐encapsulated cells showed higher survival upon storage than free cells. Also, the SEM analysis showed spherical particles of 77.92–230.13 µm in size. The physicochemical and sensory analysis revealed an interesting nutritional content in the millet yogurt. The results indicate that the SIN matrix has significant promise as probiotic encapsulating material as it may provide efficient cell protection while also providing considerable physicochemical and nutritional benefits in functional foods.
Visit‐to‐visit variability of blood pressure and risk of macrovascular and microvascular complications in patients with type 2 diabetes: A Chinese primary‐care cohort study
Authors: Deng Ying , Liu Yin , Zhang Shengchao , Yu Hanbing , Zeng Xiaozhou , An Rongrong , Chen Zhenyuan , Sun Na , Yin Xiaoxv , Dong Yue 
Published: November 2022

AbstractBackgroundWe evaluated the effects of visit‐to‐visit variability of systolic blood pressure (SBP) and diastolic blood pressure (DBP) on macrovascular and microvascular complications among patients with type 2 diabetes.MethodsA total of 11 043 patients with type 2 diabetes from primary healthcare institutions between January 2010 and June 2020 were included. The visit‐to‐visit blood pressure variability was calculated using three metrics: SD, coefficient of variation (CV), and average real variability (ARV), obtained over a 12‐month measurement period. The associations of visit‐to‐visit blood pressure variability with macrovascular and microvascular complications were evaluated using multivariate‐adjusted Cox proportional hazards models, and hazard ratio (HR) with 95% confidence interval (CI) were reported.ResultsThere were 330 macrovascular events and 542 microvascular events. Compared to those for participants with the lowest quartile of SD of SBP and DBP, increased risks were observed in patients with the highest quartile of SD of SBP and DBP for macrovascular complications (SD‐SBP: HR = 1.78, 95% CI: 1.24–2.57; SD‐DBP: HR = 2.20, 95% CI: 1.50–3.25) and microvascular complications (SD‐SBP: HR = 1.85, 95% CI: 1.39–2.46; SD‐DBP: HR = 1.82, 95% CI: 1.36–2.44). CV and ARV of SBP and DBP also had statistically significant associations with macrovascular and microvascular complications. The optimal variability of blood pressure target was SD of SBP <6.45 mm Hg and SD of DBP <4.81 mm Hg.ConclusionsVisit‐to‐visit blood pressure variability may be a potential predictor for macrovascular and microvascular complications in patients with type 2 diabetes.
Discussion on “Instrumental Variable Estimation of the Causal Hazard Ratio,” by Linbo Wang, Eric Tchetgen Tchetgen, Torben Martinussen, and Stijn Vansteelandt
Authors: Baer Benjamin R. , Strawderman Robert L. , Ertefaie Ashkan 
Published: November 2022

Abstract
We propose and study an augmented variant of the estimator proposed by Wang, Tchetgen Tchetgen, Martinussen, and Vansteelandt.
Latent profiles of maternal disrupted communication: Relations to affect and behaviour in early infancy
Authors: Khoury Jennifer E. , Cunningham Molly , Jenkins Emma , Enlow Michelle Bosquet , Lyons‐Ruth Karlen 
Published: November 2022

AbstractFew studies have examined how mothering is organized in the first months of infancy, especially regarding risk‐related interactions. Person‐centred approaches, including latent profile analysis (LPA), add valuable insights about early parenting by identifying distinct profiles of interaction. First, this study aimed to identify profiles of disrupted maternal interaction during the Still‐Face Paradigm among 181 mothers and their 3‐ to 8‐month‐old infants. Second, the study assessed how each maternal profile was related to infant affect and interactive behaviour. The LPA identified four profiles of maternal interaction: optimal, negative/intrusive, withdrawing and pervasively disrupted. The pervasively disrupted profile, in particular, has not been identified in past research. Each profile was associated with specific aspects of infant affect and behaviour. Recognition of disrupted behavioural profiles among at‐risk mothers and infants in the early months could facilitate more precise tailoring of early interventions to the needs of mothers and infants with differing profiles of interactive risk.
Novel de novo ZNF148 truncating variant causing autism spectrum disorder, attention deficit hyperactivity disorder, and intellectual disability
Authors: Miao Chunyue , Du Lin , Zhang Yu , Jia Feiyong , Shan Ling 
Published: November 2022

AbstractZNF148 gene is a Krüppel‐type transcription factor that has transcriptional regulatory function. Heterozygous variant in ZNF148 gene causes an intellectual disability syndrome characterized by global developmental delay, absence, or hypoplasia of corpus callosum, wide intracerebral ventricles, and dysmorphic facial features, while its associations with ASD and ADHD have not been reported. We report a new patient with intellectual disability, autism spectrum disorder (ASD) and attention‐deficit hyperactivity disorder (ADHD). The patient had a novel heterozygous truncating variant c.1818dupC (p.Lys607Glnfs*11) in the ZNF148 gene. This variation produces a ZNF148 truncated protein with a deletion of the C‐terminal activation domain and may destabilize the protein by affecting the transcriptional activation function. Brain MRI shows normal brain development. Here, we identify a novel ZNF148 heterozygous truncating variant in a patient with distinct phenotypes of ASD and ADHD, which expands the genotype–phenotype spectrum of ZNF148, and indicates ZNF148 is also a potential target gene for ASD.
Bariatric surgery and weight loss in the short‐ and long‐term: Evidence from NHANES 2015–2018
Authors: Xie Wubin , Johnston Stephen S. , Waggoner Jason R. , Doshi Ishita D. , Stokes Andrew C. 
Published: November 2022

SummaryThe present study aimed to examine short‐ and long‐term weight change in a nationally representative sample of US adults who reportedly underwent bariatric surgery. Individuals aged 20–64 at survey from the US National Health and Nutrition Examination Survey 2015–2018 were included in the analyses (n = 6776). The primary comparison groups include 62 participants who underwent bariatric surgery, 1531 eligible but did not receive surgery, and 5183 not eligible for bariatric surgery. After adjusting for demographic characteristics and comorbidity, adults who reported receiving bariatric surgery were 5.0 times (4.0–6.0) more likely to achieve at least 20% weight loss from maximum weight relative to those who were eligible but reported no surgery. The likelihood appeared to be higher when surgery was performed within 10 years (short‐term, PR 5.5, 95% CI: 4.0, 7.0) relative to surgeries that were performed for 10 or more years (long‐term, PR 3.6, 95% CI: 2.0, 5.3). In this nationally representative sample of US adults, respondents who received bariatric surgery achieved substantial and significant weight loss compared with those who were eligible and did not receive bariatric surgery. Weight loss appeared to be most apparent in the short term and persisted over the long term.
Spraints demonstrate small population size and reliance on fishponds for Eurasian otter (Lutra lutra) in Hong Kong
Authors: McMillan Sharne E. , Wong Anson Tsz Chun , Tang Sally Shui Yan , Yau Eugene Yu Hin , Gomersall Thomas , Wong Portia Y. H. , Vu Andy Ka Hei , Sin Simon Yung Wa , Hau Billy C. H. , Bonebrake Timothy C. 
Published: November 2022

AbstractLack of data on population sizes and resource requirements are major impediments to the effective conservation of rare species globally. The conservation of the Eurasian otter (Lutra lutra) in Hong Kong reflects many of these key challenges for elusive and difficult‐to‐study mammals. It is a rare carnivore that has narrowly escaped extirpation, now surviving within a human‐dominated environment. Using sign surveys and spraint analysis, we recorded only 40 fresh spraints from 246 otter signs locations, over 4 months of intensive sampling across 2 years. Records were restricted to the Mai Po wetlands, confirming this as the core area for Hong Kong's otter population. Molecular analysis and microsatellite genotyping identified a minimum of seven individuals, two pairs of which were likely related. The genetic and sign data together strongly indicate a small population. Fish dominated the otter diet, highlighting the importance of fishpond habitats as a premium foraging resource. Given the rapid changes surrounding the Mai Po area (especially the new Northern Metropolis Development Strategy), maintaining quality and connected habitats, in addition to sustaining commercial fishponds will be key to otter recovery and long‐term population viability in Hong Kong.
Regular protocol liver biopsy is useful to adjust immunosuppressant dose after adult liver transplantation
Authors: Narita Shohei , Miuma Satoshi , Okudaira Sadayuki , Koga Yoshito , Fukushima Masanori , Sasaki Ryu , Haraguchi Masafumi , Soyama Akihiko , Hidaka Masaaki , Miyaaki Hisamitsu , Futakuchi Mitsuru , Nagai Kazuhiro , Ichikawa Tatsuki , Eguchi Susumu , Nakao Kazuhiko 
Published: November 2022

AbstractIntroductionAdjusting immunosuppression to minimal levels post‐adult liver transplantation (LT) is critical; however, graft rejection has been reported in LT recipients with normal liver function evaluated by liver biopsy (LBx). Continual protocol liver biopsy (PLB) is performed regularly in LT recipients with normal liver function in some centers; however, its usefulness remains inadequately evaluated. This study aimed to assess retrospectively the usefulness of late PLB after adult LT.MethodsLBx evaluations of LT recipients with normal liver function and hepatitis B and C virus seronegativity were defined as PLB. The cases requiring immunosuppressive therapy for rejection findings based on Banff criteria were extracted from the PLBs, and pathological data collected before and after immunosuppressive dosage adjustment (based on modified histological activity index [HAI] score) were compared.ResultsAmong 548 LBx cases, 213 LBx in 110 recipients fulfilled the inclusion criteria for PLB. Immunosuppressive therapy after PLB was intensified in 14 LBx (6.6%) recipients (12.7%); of these, nine had late‐onset acute rejection, three had isolated perivenular inflammation, one had plasma cell‐rich rejection, and one had early chronic rejection. Follow‐up LBx after immunosuppressive dose adjustment showed improvement in the modified HAI score grading in 10 of 14 cases (71.4%). No clinical background and blood examination data, including those from the post‐LT period, immunosuppressant trough level, or examination for de novo DSA, predicted rejection in PLB. Complications of PLB were found in only three cases.ConclusionPLB is useful in the management of seemingly stable LT recipients, to discover subclinical rejection and allow for appropriate immunosuppressant dose adjustment.
Investment and the long swings of unemployment
Authors: Hoon Hian Teck , Katsimi Margarita , Zoega Gylfi 
Published: November 2022

AbstractWe estimate the medium‐term relationship between investment and unemployment over the period 1960–2017 in 20 OECD countries, a period that includes the years of the Great Recession. While neoclassical growth theory typically assumes full employment—with no effect of investment on unemployment—and New‐Keynesian models assume that such a relationship only exists in the short term at business cycle frequencies, we find that over our sample period covering more than 5 decades, a statistically significant negative relationship does exist: in decades when investment fell, unemployment increased. Panel estimation, using a measure of stock market volatility as an instrument for investment, confirms the negative relationship between investment and unemployment. High stock market volatility and low investment are associated with high unemployment, other things equal. The evidence supports both Keynes' ideas about an unemployment equilibrium as well as more recent investment‐based theories of the natural rate of unemployment.
Refusing Teachers and the Politics of Instrumentalism in Educational Policy
Authors: Carusi F. Tony 
Published: November 2022

AbstractIn this article, F. Tony Carusi considers the politics of instrumentalism performed between educational policy and research that figures the teacher as the primary means to raise student achievement. By reducing teachers to a means toward an end, policy and research work together to collapse what teachers are into what teachers are for, and in doing so, they enable discourses that privilege the instrumental specifically as ontological. In contrast to this collapse, Carusi highlights here the resistance of the ontological to the instrumental by considering what teachers are apart from what they are for. Thinking the ontological apart from the instrumental leads to a dark pedagogy in which the refusals and negations performed by teachers occur where the politics of instrumentalism that renders them as an “in‐school factor” do not see.
Gene expression meta‐analysis in patients with schizophrenia reveals up‐regulation of RGS2 and RGS16 in Brodmann Area 10
Authors: Shriebman Yaen , Yitzhaky Assif , Kosloff Mickey , Hertzberg Libi 
Published: November 2022

AbstractRegulator of G‐protein signalling (RGS) proteins inhibit signalling by G‐protein‐coupled receptors (GPCRs). GPCRs mediate the functions of several important neurotransmitters and serve as targets of many anti‐psychotics. RGS2, RGS4, RGS5 and RGS16 are located on chromosome 1q23.3–31, a locus found to be associated with schizophrenia. Although previous gene expression analysis detected down‐regulation of RGS4 expression in brain samples of patients with schizophrenia, the results were not consistent. In the present study, we performed a systematic meta‐analysis of differential RGS2, RGS4, RGS5 and RGS16 expression in Brodmann Area 10 (BA10) samples of patients with schizophrenia and from healthy controls. Two microarray datasets met the inclusion criteria (overall, 41 schizophrenia samples and 38 controls were analysed). RGS2 and RGS16 were found to be up‐regulated in BA10 samples of individuals with schizophrenia, whereas no differential expression of RGS4 and RGS5 was detected. Analysis of dorso‐lateral prefrontal cortex samples of the CommonMind Consortium (258 schizophrenia samples vs. 279 controls) further validated the results. Given their central role in inactivating G‐protein‐coupled signalling pathways, our results suggest that differential gene expression might lead to enhanced inactivation of G‐protein signalling in schizophrenia. This, in turn, suggests that additional studies are needed to further explore the consequences of the differential expression we detected, this time at the protein and functional levels.
Establishment of a laboratory‐rearing technique for the rove beetle Anotylus amicus (Coleoptera: Staphylinidae) with investigations of its life cycle, behavior and morphological variations
Authors: Okuzono Motoharu , Tokuda Makoto 
Published: November 2022

AbstractRove beetles (Staphylinidae) are one of the largest families in Coleoptera. Although the ecological features of rove beetles are important subjects in terms of understanding their diversification processes, laboratory‐rearing studies have only been conducted for a few species to date. In this study, we established a continuous rearing method for Anotylus amicus (Bernhauer, 1923) (Staphylinidae: Oxytelinae) using bell cricket food. In addition, its life cycle, behavior and morphological variations were investigated using the rearing technique. The mean duration of egg, first, second and third instars, prepupa and pupa were 4.3, 4.0, 4.0, 7.8, 1.7 and 4.7 days at 24°C, respectively. Adults and larvae used substrate, food and excrement for nesting. Mate guarding by males and associated male–male combat were observed. Head width and body size sexually varied; most males were larger than females, but some were comparable to females. Many individuals possessed undeveloped short hindwings, while some, especially large females, had long ones. As A. amicus can be reared simply, have a fairly short generation period, and exhibit interesting behavioral and morphological characteristics, A. amicus is suitable for clarifying the ecological aspects of rove beetles.
Communication with mechanically ventilated patients in intensive care units: A concept analysis
Authors: Karlsen Marte‐Marie Wallander , Holm Anna , Kvande Monica Evelyn , Dreyer Pia , Tate Judith Ann , Heyn Lena Günterberg , Happ Mary Beth 
Published: November 2022

AbstractAimsThe aim of this study was to perform a concept analysis of communication with mechanically ventilated patients in intensive care units and present a preliminary model for communication practice with these patients.DesignThe Im & Meleis approach for concept analysis guided the study.Search MethodsA literature search was performed in January 2022 in MEDLINE, Embase, CINAHL, psycINFO and Scopus, limited to 1998–2022. The main medical subject headings search terms used were artificial respiration, communication and critical care. The search resulted in 10,698 unique references.Review MethodsAfter a blinded review by two authors, 108 references were included. Core concepts and terminology related to communication with mechanically ventilated patients were defined by content analytic methods. The concepts were then grouped into main categories after proposing relationships between them. As a final step, a preliminary model for communication with mechanically ventilated patients was developed.ResultsWe identified 39 different phrases to describe the mechanically ventilated patient. A total of 60 relevant concepts describing the communication with mechanically ventilated patients in intensive care were identified. The concepts were categorized into five main categories in a conceptual map. The preliminary model encompasses the unique communication practice when interacting with mechanically ventilated patients in intensive care units.ConclusionHighlighting different perspectives of the communication between mechanically ventilated patients and providers through concept analysis has contributed to a deeper understanding of the phenomena and the complexity of communication when the patients have limited possibilities to express themselves.ImpactA clear definition of concepts is needed in the further development of guidelines and recommendations for patient care in intensive care, as well as in future research. The preliminary model will be tested further.Patient or Public ContributionNo patient or public contribution, as this is a concept analysis of previous research.
The role of group identification, self‐ and collective efficacy on secondary traumatic stress and general health in a sample of emergency medical service volunteers
Authors: Caricati Luca , De vito Martina , Panari Chiara 
Published: November 2022

AbstractThis paper reports the results of a web‐based survey on the relationship between group identification, secondary traumatic stress, and psychological distress in a sample of Italian emergency medical service volunteers. The theoretical foundation of this research was based on the social cure approach that suggests that group identification can increase people's wellbeing by enhancing the sense of social support and mastery. Responses from 1214 volunteers (50% men) were collected and structural equation modeling was performed to assess direct and indirect effect of group identification on both secondary traumatic stress and psychological distress. Results supported expectations, and indicated that group identification was associated with decreased secondary traumatic stress and psychological distress: this relation was both direct and mediated by self‐efficacy and collective efficacy. Self‐efficacy and collective efficacy completely mediated the relationship between group identification and secondary traumatic stress, while mediation was partial for the relationship between group identification and psychological distress. Moreover, our findings revealed that collective efficacy had a higher impact on psychological distress than on secondary traumatic stress. Self‐efficacy, instead, had a significant negative effect on both secondary traumatic stress and psychological distress. Finally, secondary traumatic stress had a strong relationship with psychological distress. The practical implications for volunteers' wellbeing and volunteer association are discussed in view of the need to improve collective positive resources.