bluuebunny/crossref_metadata_2025_split huggingface dataset:
Low-dose computed tomography for lung cancer screening in Anhui, China: A randomized controlled trial
Authors: Rong Feng , Shi Rui , Hu Lili , Chen Ran , Wang Daoyue , Lv Xiazhi , Zhao Yong , Huang Wei , Yang Yang , Zhou Hongyang , Hong Kaige 
Published: December 2022

BackgroundLung cancer is the leading cause of cancer-related death worldwide, with risk factors such as age and smoking. Low-dose computed tomography screening can reduce lung cancer mortality. However, its effectiveness in Asian populations remains unclear. Most Asian women with lung cancer are non-smokers who have not been screened. We conducted a randomized controlled trial to evaluate the performance of low-dose computed tomography screening in a Chinese population, including high-risk smokers and non-smokers exposed to passive smoking. The baseline data are reported in this study.MethodsBetween May and December 2019, eligible participants were randomized in a ratio of 1:1:1 to a screening (two arms) or control cohort. Non-calcified nodules/masses with a diameter &gt;4 mm on low-dose computed tomography were considered positive findings.ResultsIn total, 600 patients (mean age, 59.1 ± 6.9 years) underwent low-dose computed tomography. Women accounted for 31.5% (189/600) of patients; 89.9% (170/189) were non-smokers/passive smokers. At baseline, the incidence of lung cancer was 1.8% (11/600). The incidence of lung cancer was significantly lower in smokers than in female non-smokers/passive smokers (1.0% [4/415] vs. 4.1% [7/170], respectively; P=0.017). Stage 0–I lung cancer accounted for 90.9% (10/11) of cases.ConclusionsWe demonstrate the importance of including active smokers and female non-smokers/passive smokers in lung cancer screening programs. Further studies are needed to explore the risk factors, and long-term cost–benefit of screening Asian non-smoking women.Clinical trial registrationhttp://chictr.org.cn/showproj.aspx?proj=39003, identifier ChiCTR1900023197.
Process of diagnosis and treatment of chronic cough in children at primary hospitals
Authors: Shen Hua-Qin , Zhang Yan-Han , Zhang Jing , Sheng Qiu-Ming 
Published: December 2022

ObjectiveThis study aimed to establish a process for the diagnosis and treatment of chronic cough in children suitable at primary hospitals and improve the treatment efficacy rate and improve health economic indicators.MethodsChildren who visited the Department of Pediatrics, Affiliated Zhou Pu Hospital of the Shanghai Health Medical College from January to December 2021 were randomly assigned to the intervention group (n = 206), in which the diagnosis and treatment process proposed here was applied, and a control group (n = 211) that did not follow the intervention pathway and followed a pathway with the doctors usual practice based on his/her previous experience. Patients were followed up and data were collected at weeks 0 (time of enrollment), 2, 4, 8, and 12 to evaluate the efficacy rate and clinical value.Results(1) No significant differences were detected between the two groups in baseline characteristics, including gender, age, duration of cough (weeks), history of allergy in children and parents, and smoking of family members living in the same household (p &gt; 0.05); (2) During the follow-up, all cough symptom scores of the intervention group were lower than the control group. Additionally, at week 12, the treatment efficacy rate of the intervention group (91.70%) was significantly higher than the control group (69.20%) (p &lt; 0.05); (3) The quality of life of children in both groups at week 12 was improved compared to the first visit. However, the total score of the intervention group was significantly higher than the control group (p &lt; 0.05); (4) At week 12, the referral rate was significantly lower in the intervention group (11.17%) than in the control group (21.33%); (5) The intervention group was better than the control group for the mean monthly medication costs, number of days on errors in childhood, and number of days mistakenly worked by family members at week 12 (p &lt; 0.05).ConclusionThe current process of diagnosis and treatment of chronic cough in children at primary hospitals can improve the effective diagnosis and treatment rate, the quality of life, and other parameters, with good effectiveness and feasibility.
Effects of traditional Chinese herb hot compress combined with therapeutic exercise on pain, proprioception, and functional performance among older adults with knee osteoarthritis: A randomized controlled trial
Authors: Wang Jingwen , Liu Wei , Fu Haitao 
Published: December 2022

Background: Knee osteoarthritis (KOA) is one of the most common chronic progressive diseases with degenerative destruction of articular cartilage and bone, leading to knee pain, impaired proprioception, and reduced functional performance. This study was to investigate the effects of an 8-week Traditional Chinese herb hot compress (TCHHC) combined with therapeutic exercise (TE) on pain, proprioception, and functional performance among older adults with KOA.Methods: Twenty-seven older adults with KOA were recruited and randomly assigned to the TCHHC + TE or TE groups. Thirteen participants received TCHHC + TE, and fourteen received TE. At pre- (week 0) and post-intervention (week 9), their pain, joint proprioception, and functional performance were measured. Two-way ANOVA with repeated measures was adopted to analyze the data.Results: Compared with week 0, the pain score, proprioception thresholds of knee extension and ankle plantarflexion, and the times of TUG and 20-m walk tests decreased more significantly in the TCHHC + TE group than in the TE group at week 9.Conclusion: Compared with TE, the 8-week TCHHC + TE was superior in relieving pain, recovering proprioception, and improving functional performance among older adults with KOA. It is recommended that TCHHC should be adopted prior to TE to enhance the effects of KOA rehabilitation.
No moderating effect of coping skills on the association between bullying experience and self-esteem: Results from K-CHILD study
Authors: Saimon Yukino , Doi Satomi , Fujiwara Takeo 
Published: December 2022

IntroductionFew studies have investigated the moderating effect of coping skills on the association between bullying experience and low self-esteem. The aim of this study was to examine whether coping skills have a moderating effect on the association between bullying experience and self-esteem among Japanese students.MethodsData from the population-based Kochi Child Health Impact of Living Difficulty (K-CHILD) study conducted in 2016 were analyzed. Participants included fifth-and eighth-grade students living in Kochi Prefecture, Japan. A questionnaire for the students (n = 5,991) assessed the bullying experience, self-esteem (the Japanese Edition of the Harter’s Perceived Competence Scale for Children), and coping skills that comprised six types (The shortened version of coping skills for elementary school children). Multivariate linear regression analyses were conducted to examine the association between bullying experience and self-esteem and then the moderating effects of six types of coping as interaction terms on the association were considered.ResultsBullying experience was inversely associated with self-esteem. All six types of coping did not moderate the relationship between bullying experience and low self-esteem even after adjusting for cofounders (all P for interaction &gt; 0.15).ConclusionCoping skills did not moderate the association between bullying experience and self-esteem, suggesting that intervention to boost coping skills to mitigate the adverse effect of bullying experience may not be promising.
Breathomics profiling of metabolic pathways affected by major depression: Possibilities and limitations
Authors: Gbaoui Laila , Fachet Melanie , Lüno Marian , Meyer-Lotz Gabriele , Frodl Thomas , Hoeschen Christoph 
Published: December 2022

BackgroundMajor depressive disorder (MDD) is one of the most common psychiatric disorders with multifactorial etiologies. Metabolomics has recently emerged as a particularly potential quantitative tool that provides a multi-parametric signature specific to several mechanisms underlying the heterogeneous pathophysiology of MDD. The main purpose of the present study was to investigate possibilities and limitations of breath-based metabolomics, breathomics patterns to discriminate MDD patients from healthy controls (HCs) and identify the altered metabolic pathways in MDD.MethodsBreath samples were collected in Tedlar bags at awakening, 30 and 60 min after awakening from 26 patients with MDD and 25 HCs. The non-targeted breathomics analysis was carried out by proton transfer reaction mass spectrometry. The univariate analysis was first performed by T-test to rank potential biomarkers. The metabolomic pathway analysis and hierarchical clustering analysis (HCA) were performed to group the significant metabolites involved in the same metabolic pathways or networks. Moreover, a support vector machine (SVM) predictive model was built to identify the potential metabolites in the altered pathways and clusters. The accuracy of the SVM model was evaluated by receiver operating characteristics (ROC) analysis.ResultsA total of 23 differential exhaled breath metabolites were significantly altered in patients with MDD compared with HCs and mapped in five significant metabolic pathways including aminoacyl-tRNA biosynthesis (p = 0.0055), branched chain amino acids valine, leucine and isoleucine biosynthesis (p = 0.0060), glycolysis and gluconeogenesis (p = 0.0067), nicotinate and nicotinamide metabolism (p = 0.0213) and pyruvate metabolism (p = 0.0440). Moreover, the SVM predictive model showed that butylamine (p = 0.0005, pFDR=0.0006), 3-methylpyridine (p = 0.0002, pFDR = 0.0012), endogenous aliphatic ethanol isotope (p = 0.0073, pFDR = 0.0174), valeric acid (p = 0.005, pFDR = 0.0162) and isoprene (p = 0.038, pFDR = 0.045) were potential metabolites within identified clusters with HCA and altered pathways, and discriminated between patients with MDD and non-depressed ones with high sensitivity (0.88), specificity (0.96) and area under curve of ROC (0.96).ConclusionAccording to the results of this study, the non-targeted breathomics analysis with high-throughput sensitive analytical technologies coupled to advanced computational tools approaches offer completely new insights into peripheral biochemical changes in MDD.
Investigation of Soft Magnetic Material Fe-6.5Si Fracture Obtained by Additive Manufacturing
Authors: Agapovichev Anton V. , Khaimovich Alexander I. , Erisov Yaroslav A. , Ryazanov Mikhail V. 
Published: December 2022

The freeform capability additive manufacturing (AM) technique and the magnetic efficiency of Fe-6.5Si steel have the potential for the development of electromechanical component designs with thin body sections. Moreover, the directional anisotropy of the material, which is formed during growth, improves the magnetic and electrical properties of Fe-6.5 wt%Si. We obtained the range of optimal technological modes of Laser Power Bed Fusion process (volume energy density (VED) of 100–140 J/mm3, scanning speed of 750–500 mm/s) to produce the samples from Fe-6.5 wt%Si powder, but even at the best of them cracks may appear. The optical microscopy and SEM with EDX analysis of the laser-fabricated structures are applied for investigation of this phenomena. We detected a carbon content at the boundaries of the cracks. This suggests that one of the reasons for the crack formation is the presence of Fe3C in the area of the ordered α’FeSi (B2)+Fe3Si(D03) phases. Quantitative analysis based on crack initiation criteria (CIC) showed that the safe level of internal stresses in terms of the CIC criteria in the area of discontinuities is exceeded by almost 190%. Local precipitates of carbides in the area of cracks are explained by the heterogeneity and high dynamics of temperature fields, as well as the transfer of substances due to Marangoni convection, which, as a result, contributes to a significant segregation of elements and the formation of precipitate phases.
RATIONALITY IN SCIENCE: A COMPARISON STUDY BETWEEN IBNU RUSYD AND RENE DESCARTES
Authors: Huringiin Nabila , Indallah Sayyid Muhammad 
Published: December 2022

This article aims to compare the concept of rationality between Rene Descartes and Ibn Rushd. Namely Rene Descart who only uses reason or ratio, while Ibn Rushd who uses reason and revelation in reaching the ultimate truth. This article is a literature review where research data are taken from books and written sources that discuss the two figures. The method used in compiling this article is comparative descriptive with a philosophical approach. The results of this study conclude that the two concepts have something in common, namely the ratio or reason used to reach the truth. Even though they use the same ratio or reason, the main sources of knowledge between the two are very different. According to Rene Descartes, those who only use reason or reason will be able to reach the ultimate truth. Meanwhile, Ibn with his rationality based on revelation will reach the ultimate truth.
Artikel ini bertujuan untuk membandingkan konsep rasionalitas antara Rene Descartes dan Ibnu Rusyd. Yaitu Rene Descart yang hanya menggunakan akal atau rasio, sedangkan Ibnu Rusyd yang menggunakan akal dan wahyu dalam mencapai kebenaran yang hakiki. Artikel ini adalah kajian pustaka dimana data penelitian diambil dari buku-buku dan sumber-sumber yang tertulis yang membahas antara kedua tokoh tersebut. Metode yang digunakan dalam menyusun artikel ini adalah deskriptif komparatif dengan pendekatan filosofis. Hasil dari kajian ini menyimpulkan, bahwasannya kedua konsep tersebut memiliki kesamaan yaitu pada rasio atau nalar yang digunakan untuk mencapai kebenaran tersebut. Meskipun menggunakan rasio atau nalar yang sama namun sember utama ilmu pengetahuan antara keduanya sangat berbeda. Menurut Rene Descartes yang hanya menggunakan akal atau rasio akan dapat mencapai kebenaran yang hakiki. Sedangkan Ibnu dengan rasionalitasnya dengan berlandaskan wahyu akan mencapai kebenaran hakiki.
CHANGES AND DEVELOPMENT OF THE MEANING OF SECULARISM IN ISLAMIC THOUGHT
Authors: Abdurrahman Usman Zulkifli 
Published: December 2022

Abstract: Secularism is one of the most controversial concepts in Islamic thought. This concept which is rooted in Western history is not only opposed and rejected by some Muslim thinkers, but also critically accepted by some other Muslim thinkers. Muslim thinkers with various scientific backgrounds such as Abdul Karim Sorous, Nasir Hamid Abu Zayd, Nurcholis Madjid tend to accept the concept critically. This paper with descriptive analysis method shows that the elaboration of the concept of secularism by these thinkers not only shows the problematic and controversial concept of secularism, but also proves that the concept is transformed into the Islamic tradition both socio-historical, political, and philosophical.
Sekularisme menjadi salah satu konsep yang paling kontroversial dalam pemikiran Islam. Konsep yang berakar dari sejarah Barat ini bukan hanya ditentang dan ditolak oleh sebagian pemikir Muslim, namun juga diterima secara kritis oleh sebagian pemikir Muslim kontemporer. Pembahasan artikel ini dengan metode komparatif dan deskriptif kualitatif serta dengan pendekatan filosofis menemukan bahwa pemikir-pemikir muslim mengkritik sekularisme model Barat, dan merekonstruksi makna sekularisme sesuai dengan konteks sosial, politik, dan kepercayaan masyarakat muslim. Atas dasar temuan ini, artikel ini menyimpulkan bahwa konsep sekularisme mengalami transformasi dan pergeseran makna dalam pemikiran Islam.

Keywords: Secularism, Islamic Thought, Transformation, Abdul Karim Sorouh, Nasr Hamid Abu Zayd

Abstrak: Sekularisme menjadi salah satu konsep yang paling kontroversial dalam pemikiran Islam. Konsep yang berakar dari sejarah Barat ini bukan hanya ditentang dan ditolak oleh sebagian pemikir Muslim, namun juga diterima secara kritis oleh sebagian pemikir Muslim lainnya. Pemikir-pemikir Muslim dengan berbagai latar belakang keilmuan seperti Abdul Karim Sorous, Nasir Hamid Abu Zayd, Nurcholis Madjid cenderung menerima konsep tersebut secara kritis. Makalah ini dengan metode deskriptif analisis menunjukkan bahwa elaborasi konsep sekularisme oleh pemikir-pemikir tersebut bukan hanya menunjukkan betama problematis dan kontroversialnya konsep sekularisme, namun membuktikan pula bahwa konsep tersebut ditransformasi ke dalam tradisi Islam baik secara sosio-historis, politik, maupun filosofis.

Kata kunci: Sekularisme, Pemikiran Islam, Transformasi, Abdul Karim Sorouh, Nasr Hamid Abu Zayd
ANALYSIS OF THE EFFECTIVENESS OF MUHAMMADIYAH, CILEDUG BRANCH, TANGERANG CITY IN THE MEMBERSHIP CADERIZATION PROCESS
Authors: Fatayan Arum , Ayu Sartika , Bachrudin Aska Amalia 
Published: December 2022

Muhammadiyah is the largest Islam movement organization in Indonesia, as well as a renewal movement guided by the Al-Quran and Hadits. Muhammadiyah cadres arepeople who are elected as members to be responsible for leading Muhammadiyah. The purpose of this study was to find out and explore the process of regeneration at the Ciledug Branch of Muhammadiyah which was considered lacking in regeneration. Muhammadiyah Ciledug Branch is quite active in regular Muhammadiyah study activities. This study uses qualitative research methods to collect data from the Ciledug Branch Manager.Tangerang City through interviews, observations, and documentation. In the results of this study, it turned out that the Muhammadiyah Ciledug Branch was sufficient in membership regeneration, through business charity, routine studies were able could be agents of enewal in improving the quality of cadre membership of Muhammadiyah Ciledug Branch, Tangerang City though business charities.
Muhammadiyah ialah organisasi gerakan islam yang terbesar di Indonesia, selain itu sebagai gerakan pembaharuan berpedoman pada Al-Quran dan Hadits. Kader Muhammadiyah adalah orang yang dipilih sebagai anggota untuk dapat bertanggung jawab dalam memimpin Muhammadiyah. Tujuan penelitian ini dilakukan untuk mengetahui dan mendalami proses kaderisasi pada Muhammadiyah Cabang Ciledug dianggap kurang dalam melakukan kaderisasi. Muhammadiyah Cabang Ciledug termasuk cukup aktif dalam kegiatan kajian Muhammadiyah secara rutin. Penelitian ini menggunakan metode penelitian kualitatif mengumpulkan data dari Pimpinan Cabang Ciledug Kota Tangerang melalui wawancara, observasi, dan dokumentasi. Pada hasil dari penelitian ini ternyata Muhammadiyah cabang ciledug cukup dalam kaderisasi keanggotaan, melalui amal usaha, kajian rutin mampu menghasilkan kaderisasi Muhammadiyah yang berkomitmen, berwawasan luas dalam ajaran islam, dapat menjadi agen pembaharuan dalam meningkatkan kualitas kaderisasi keanggotaan Muhammadiyah Cabang Ciledug Kota Tangerang melalui amal usaha.
Supporting Students Become A Smart User Through TEDTalk Application
Authors: Chotimah Chusnul , Handayani Fitri 
Published: December 2022

Abstract
This research is aboutTed Talk application that support the students being smart people by smartphone. TED Talk applications can help the students in learning English for four skills such as reading writing listening and speaking. This app offers kids and parents the opportunity to explore and view videos from the renowned TED (Technology, Entertainment, Design) conferences, which feature a mix of interesting speakers from all walks of life. The researcher believes that this application can support the students being smart people by smartphone. The purpose of this research is to support the students being smart people by their smartphone using TED Talk application. This research did about six months in As-Syafi’iyah Islamic University. The participants in this research are 20 college students on fifth semester in speaking for academic purposes subject. The method of this research is descriptive qualitative. The instruments that used in this research are interview and observation. And based the data, the researcher can conclude that using TED Talk as application that support the students being smart people by smartphone is very useful for all students. The students can increase their knowledge and skills in English. They can watch videos or listening audio to get some ideas for speaking practice.
THE ENGLISH PROFICIENCY OF TOURIST ACTORS IN KLATEN
Authors: Sholihah Umi , Sumekto Didik Rinan 
Published: December 2022

This study aims to know the English proficiency of tourist actors in Klaten. The data of this research consist of primary data and secondary data. Primary data are the data gotten from English proficiency of tourist actors in Klaten, especially in speaking skill. Meanwhile, secondary data are the data from the tourism department of Klaten. This research method is descriptive quantitative. The subjects of this study are tourist actors in temple and water tourist spots in Klaten, which consists of officers, sellers, parking attendants, security, and other tourist actors. The temple tourist spots are Plaosan temple and Sojiwan temple. Meanwhile, the water tourist spots are Umbul Ponggok and Umbul Cokro (OMAC). The choice of those spots is depended on the most foreign tourists among that type of tourist destinations. The result of the study shows that the English proficiency of tourist actors in temple tourist attractions is higher (50%) than water tourist attractions (8,33%). In temple tourist attractions, tourist actors who have high English proficiency is 50%, average is 37.5%, low is 12.5%. In water tourist attractions, tourist actors who have high English proficiency is 8.33%, average is 29.16%, low is 62.5%. This study also got other data that tourist actors in Klaten have important role to support tourism industry in Klaten to attract tourists, both domestic and foreign, but their awareness of it is still low. Most of them still rely on domestic tourists than foreigners.
La pastorale d’un franciscain dans le Midi de la France à la fin du XIIIe siècle d’après un recueil d'exempla inédit (ms lat. 3555 de la BNF)
Authors: Polo de Beaulieu Marie-Anne 
Published: December 2022

A Franciscan’s Preaching in Southern France at the End of the Thirteenth Century from an Unpublished Collection of Exempta (ms lat. 3555 of the BNF).
The study and analysis of Latin manuscript 3555 of the BNF allow us to place the collection of exempla it contained in a pastoral project led by Franciscans, surely coming from the convent of Montpellier. The study of the sources and the presentation of the collection reveal a relatively low cultural level or an intentional simplicity on the part of its anonymous author, offset by use of a near journalistic style in which the mention of place names served as auctoritas. The abundance of these topographical mentions defines an area of pastoral activity focused on Languedoc with undeniable Hispanic links. As far as the diffusion of this collection is concerned, a few leads have been explored, as much in the genre (Speculum laicorum, Scala coeli) as in Franciscan hagiographical litterature, centered on saint François.
La mort des saints dans les Vies et les procès de canonisation du Midi de la France (XIe-XIVe siècle)
Authors: Sigal Pierre-André 
Published: December 2022

Death in Lives of saints and canonization proceedings in Southern France.
Seventeen Lives and four canonization proceedings (mid-XIth till the end of XIVth century) from southern Aquitaine, Languedoc and Provence detail the death of some local saints, most of them abbots or bishops. They faced death happyly, supported by their entourage where medical attendants found an important place from the Xlllth onwards. The saint prepared his death by prayers, a mass-attendance and by hearing of readings. He received the Viaticum and the extreme unction. We notice an evolution in the evocation of the death scenery : usually tradi-tionnal and quick among the Lives of the Xlth and Xllth centuries, it became more developped in the canonization proceedings of the XIVth century. Furthermore these proceedings stressed the supernatural manifestations affecting the corpse. In a few cases, the faithful of the saint got a vision which strengthened their belief in the holiness of the dead man.