bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisa Sisip Transformator Distribusi Terhadap Perbaikan Overload Dan Tegangan Ujung Gardu BNS-0126 Di PT Pln (Persero) Up3 Barabai
Authors: Pebrisasvian Ardina Tri , Karim Saiful 
Published: March 2022

Gardu BNS-0126 yang terletak pada Penyulang BRB08 dalam data pembebanannya mencapai 124,17% (± 62,085 kVA) dari kapasitasnya yaitu 50 kVA dengan tegangan ujung sebesar 205V dan mengalami penurunan (drop voltage) sebesar 12%. Pembebanan tersebut melampaui dari kapasitas maksimum trafo standar 80%, yang berpotensi pada kerugian secara material dan finansial bagi PT PLN (Persero) UP3 Barabai. Jatuh tegangan yang diakibatkan dari hal tersebut sudah melebihi dari SPLNT6.001-2013 sebesar -±10% untuk tegangan rendah. Mempertimbangkan matriks pada Health Index assessment tier-1 Trafo Distribusi, terkait presentase pembebanan trafo berada pada kategori buruk karena dibebani ≥100%. Untuk mengatasi hal tersebut dapat diterapkan yaitu pemasangan transformator sisipan. Dengan pembebanan yang semula dari 124.17% menjadi 46,646% dari kapasitas 50kVA, kemudian tegangan ujung pada Gardu BNS-0126 dengan adanya sisip trafo semula sebesar 205 V dengan jatuh tegangan sebesar 12,0% naik menjadi 212 V dengan prosentase jatuh tegangan yang menurun sampai dengan 8,2%. Pelaksanaan sisip trafo untuk gardu BNS-0126 efektif untuk mengatasi kelebihan beban (overload) dan perbaikan tegangan ujung Kata Kunci : Sisip Trafo, Uprating Trafo, Transformator
ANALISIS DAN RANCANGAN SISTEM INFORMASI MANAJEMEN KEBENCANAAN WILAYAH KALIMANTAN SELATAN
Authors: Muflih M Muflih 
Published: March 2022

Kalimantan Selatan adalah salah satu provinsi di wilayah negara indonesia yang berada di pulau kalimantan, provinsi kalimantan selatan terdiri dari 13 kabupaten/kota, 153 kecamatan, 144 kelurahan dan 1.864 desa dengan jumlah penduduk 4.303.979 jiwa (berdasarkan data BPS tahun 2020). Pada tahun 2021 berdasarkan data BPBD Provinsi Kalimantan Selatan telah terjadi bencana besar yang dialami oleh masyarakat kalimantan selatan, dimana banjir dan tanah longsor terjadi secara bersamaan yang menyebabkan kegiatan masyarakat lumpuh total. Bencana banjir dan tanah longsor melanda 11 kabupaten/kota di kalimantan selatan. Pada 14 Januari 2021, status wilayah kalimantan selatan dinaikkan menjadi tanggap darurat banjir, bencana banjir terjadi dengan ketinggian air yang beragam, yaitu: 30 sentimeter, 50 sentimeter, 2 meter, dan 3 meter. Perkembangan teknologi informasi dan komunikasi berkembang sangat pesat seperti penggunaan smartphone yang terhubung dengan internet, faksimili, komputer, dan satelit dalam berbagai aktivitas sarana berkomunikasi dan memudahkan dalam melakukan pekerjaan. Sistem Informasi Manajemen adalah sebuah sistem manusia atau mesin yang terpadu (integrated) untuk menyajikan informasi guna mendukung fungsi operasi, manajemen, dan pengambilan keputusan dalam sebuah organisasi. Penelitian ini memberikan kontribusi kepada pihak terkait yaitu sebuah aplikasi tentang Sistem Informasi Manajemen Kebencanaan yang dapat mengelola berbagai macam data seperti data bencana, data terdampak, data logistik, pemetaan wilayah serta membantu untuk menjadi dasar dalam pengambilan keputusan baik dari pihak provinsi, kota/kabupaten maupun unsur koordinasi dibawahnya dan hasil laporan dari Sistem Informasi Manajemen Kebencanaan bisa dijadikan bahan evaluasi untuk kedepannya agar menghasilkan suatu kebijakan yang tanggap terhadap bencana di wilayah provinsi kalimantan selatan.
PELAYANAN PUBLIK BERBASIS ONLINE DI DESA (STUDI PADA EMPAT DESA DI KECAMATAN JATINANGOR)
Authors: Ikhbaluddin Ikhbaluddin 
Published: March 2022

Villages as one of the sub-systems of the government in Indonesia that carry out governance functions is at the forefront in providing services to the community. Especially, it is very essential in the midst of the current demands for easy, cheap, and fast services. One alternative solution to these demands is the use of information technology in the field of government (e-government), such as a website-based online service media. However, in reality, the villages that are used for this research location generally still provide services to the community in a conventional manner. Even when the websites are available, they do not meet the standards in e-government development. The method used in this research is qualitative with a descriptive approach, and with data collection techniques through interviews and observation. The study concludes that Cibeusi Village, Hegarmanah Village, Cileles Village, and Cilayung Village are still not optimal in utilizing website media as an alternative for online public services. Moreover, the necessary features related to online public services, namely information, interactions, and transactions are still not yet available.
Keywords: Villages, Online Public Services
Bioprinting of Decellularized Porcine Cardiac Tissue for Large-Scale Aortic Models
Authors: Oropeza Beu P. , Adams Jason R. , Furth Michael E. , Chessa Jack , Boland Thomas 
Published: March 2022

Bioprinting is an emerging technique used to layer extrudable materials and cells into simple constructs to engineer tissue or arrive at in vitro organ models. Although many examples of bioprinted tissues exist, many lack the biochemical complexity found in the native extracellular matrix. Therefore, the resulting tissues may be less competent than native tissues—this can be especially problematic for tissues that need strong mechanical properties, such as cardiac or those found in the great vessels. Decellularization of native tissues combined with processing for bioprinting may improve the cellular environment for proliferation, biochemical signaling, and improved mechanical characteristics for better outcomes. Whole porcine hearts were decellularized using a series of detergents, followed by lyophilization and mechanical grinding in order to produce a fine powder. Temperature-controlled enzymatic digestion was done to allow for the resuspension of the decellularized extracellular matrix into a pre-gel solution. Using a commercial extrusion bioprinter with a temperature-controlled printhead, a 1:1 scale model of a human ascending aorta and dog bone shaped structures were printed into a reservoir of alginate and xanthium gum then allowed to crosslink at 37C. The bioengineered aortic construct was monitored for cell adhesion, survival, and proliferation through fluorescent microscopy. The dog bone structure was subjected to tensile mechanical testing in order to determine structural and mechanical patterns for comparison to native tissue structures. The stability of the engineered structure was maintained throughout the printing process, allowing for a final structure that upheld the dimensions of the original Computer-Aided Design model. The decellularized ECM (Ē = 920 kPa) exhibited almost three times greater elasticity than the porcine cardiac tissue (Ē = 330 kPa). Similarly, the porcine cardiac tissue displayed two times the deformation than that of the printed decellularized ECM. Cell proliferation and attachment were observed during the in vitro cell survivability assessment of human aortic smooth muscle cells within the extracellular matrix, along with no morphological abnormalities to the cell structure. These observations allow us to report the ability to bioprint mechanically stable, cell-laden structures that serve as a bridge in the current knowledge gap, which could lead to future work involving complex, large-scale tissue models.
A Multimodal Score Accurately Classifies Fontan Failure and Late Mortality in Adult Fontan Patients
Authors: Kramer Peter , Schleiger Anastasia , Schafstedde Marie , Danne Friederike , Nordmeyer Johannes , Berger Felix , Ovroutski Stanislav 
Published: March 2022

ObjectivesDespite the outstanding success of the Fontan operation, it is a palliative procedure and a substantial number of patients experience late failure of the Fontan circulation. Clinical presentation and hemodynamic phenotypes of Fontan failure are considerably variable. While various parameters have been identified as risk factors for late Fontan failure, a feasible score to classify Fontan failure and possibly allow timely risk stratification is lacking. Here, we explored the possibility of developing a score based on hemodynamic, clinical and laboratory parameters to classify Fontan failure and mortality.MethodsWe performed a retrospective study in our cohort of adult Fontan patients from two institutions [n = 198, median follow-up after Fontan 20.3 (IQR 15.6–24.3) years], identifying those patients with clinical Fontan failure (n = 52, 26.3%). Various hemodynamic, echocardiographic, laboratory and clinical data were recorded and differences between patients with and without Fontan failure were analyzed. We composed a Fontan Failure Score containing 15 parameters associated with Fontan failure and/or mortality and assessed its accuracy to discriminate between patients with and without late Fontan failure as well as late mortality and survival.ResultsLate failure occurred at a median of 18.2 (IQR 9.1–21.1) years after Fontan completion. Mortality associated with Fontan failure was substantial (25/52, 48.1%) with freedom of death/transplantation/take-down of 64% at 5 years and 36% at 10 years after onset of Fontan failure, respectively. Patients with Fontan failure had a significantly higher median Fontan Failure Score compared to non-failing Fontan patients [8 points (IQR 5–10) vs. 2 points (IQR 1-5), p &lt; 0.001]. The score accurately classifies Fontan failure as well as mortality as assessed with receiver operating characteristic analysis. Area under the curve of the Fontan Failure Score was 0.963 (95% CI 0.921; 0.985, p &lt; 0.001) to discriminate failure and 0.916 (95% CI 0.873; 0.959, p &lt; 0.001) to classify mortality.ConclusionWe have developed an uncomplex yet remarkably accurate score to classify Fontan failure and late mortality in adult Fontan patients. Prospective validation and most likely refinement and calibration of the score in larger and preferably multi-institutional cohorts is required to assess its potential to predict the risk of Fontan failure and late mortality.
Identification of Specific Coronary Artery Disease Phenotypes Implicating Differential Pathophysiologies
Authors: Krohn Jona B. , Nguyen Y Nhi , Akhavanpoor Mohammadreza , Erbel Christian , Domschke Gabriele , Linden Fabian , Kleber Marcus E. , Delgado Graciela , März Winfried , Katus Hugo A. , Gleissner Christian A. 
Published: March 2022

Background and AimsThe roles of multiple risk factors of coronary artery disease (CAD) are well established. Commonly, CAD is considered as a single disease entity. We wish to examine whether coronary angiography allows to identify distinct CAD phenotypes associated with major risk factors and differences in prognosis.MethodsIn a cohort of 4,344 patients undergoing coronary angiography at Heidelberg University Hospital between 2014 and 2016, cluster analysis of angiographic reports identified subgroups with similar patterns of spatial distribution of high-grade stenoses. Clusters were independently confirmed in 3,129 patients from the LURIC study.ResultsFour clusters were identified: cluster one lacking critical stenoses comprised the highest percentage of women with the lowest cardiovascular risk. Patients in cluster two exhibiting high-grade stenosis of the proximal RCA had a high prevalence of the metabolic syndrome, and showed the highest levels of inflammatory biomarkers. Cluster three with predominant proximal LAD stenosis frequently presented with acute coronary syndrome and elevated troponin levels. Cluster four with high-grade stenoses throughout had the oldest patients with the highest overall cardiovascular risk. All-cause and cardiovascular mortality differed significantly between the clusters.ConclusionsWe identified four phenotypic subgroups of CAD bearing distinct demographic and biochemical characteristics with differences in prognosis, which may indicate multiple disease entities currently summarized as CAD.
Simulation of Fracturing and Well Pattern Optimization of Fractured Tight Sandstone Reservoirs
Authors: Liao Jianbo , Zhang Zhongyi , Tang Haizhong , Yang Jun , Zhang Xiaolei , Wang Bing 
Published: March 2022

The fracturing and well pattern optimization of fractured reservoirs is a hot spot in petroleum engineering. In this study, taking the tight oil reservoirs of the Yanchang Formation in the Ordos Basin as an example, an optimized plan of hydraulic fracturing and well pattern deployment of the fractured tight reservoir were systematically studied using a fluid-solid coupling model. The results show that the Chang 6 Member of Yanchang Formation mainly develop feldspar sandstone. A large number of vertical fractures are developed in Chang 6 Member, and they have significant shearing properties. The target sandstone reservoir is in the mid-diagenetic A stage. Natural fractures have a significant effect on the extension of hydraulic fractures. When the fracturing direction is parallel to the main strike of natural fractures, the extension distance of the hydraulic fractures is long and the fracturing scale is large; however, when the fracturing direction is orthogonal or oblique to the main strike of natural fractures, the extension distance of the hydraulic fractures is limited. Statistics show that the average length of hydraulic fractures when fracturing parallel to natural fractures is 1.3 times of that when fracturing perpendicular to natural fractures. In addition, after optimization of fracturing parameters, we found that the displacement should be controlled at 2–3 cubic meters/min, and the sand ratio should be controlled at 25%. The smaller the horizontal minimum principal stress difference between the fracturing layer and the shielding layer, the lower the elastic modulus, and the easier it is to control the fracture height. Microseismic monitoring results show that the half-fracture length and fracture height are mainly distributed in 80–140 m and 15–25 m, respectively. The optimized fracture half-length was 120 m and the half-fracture height was 20 m. Finally, the well pattern of the target layer is optimized considering natural fractures. Through this study, we found that the reverse five-spot well pattern is suitable for the efficient development of tight oil reservoirs of the Chang 6 Member in this area.
Differences Between Cancer-Specific Survival of Patients With Anaplastic and Primary Squamous Cell Thyroid Carcinoma and Factors Influencing Prognosis: A SEER Database Analysis
Authors: Jin Shuai , Liu Xiangmei , Peng Dandan , Li Dahuan , Ye Yuan-Nong 
Published: March 2022

PurposeAnaplastic thyroid carcinoma (ATC) and primary squamous cell carcinoma of the thyroid (PSCCTh) have similar histological findings and are currently treated using the same approaches; however, the characteristics and prognosis of these cancers are poorly researched. The objective of this study was to determine the differences in characteristics between ATC and PSCCTh and establish prognostic models.Patients and MethodsAll variables of patients with ATC and PSCCTh, diagnosed from 2004–2015, were retrieved from the Surveillance, Epidemiology, and End Results Program (SEER) database. Percentage differences for categorical data were compared using the Chi-square test. Kaplan-Meier curves, log-rank test, and Cox-regression for survival analysis, and C-index value was used to evaluate the performance of the prognostic models.ResultsAfter application of the inclusion and exclusion criteria, a total of 1164 ATC and 124 PSCCTh patients, diagnosed from 2004 to 2015, were included in the study. There were no differences in sex, ethnicity, age, marital status, or percentage of proximal metastases between the two cancers; however, radiotherapy, chemotherapy, incidence of surgical treatment, and presence of multiple primary tumors were higher in patients with ATC than those with PSCCTh. Further cancer-specific survival (CSS) of patients with PSCCTh was better than that of patients with ATC. Prognostic factors were not identical for the two cancers. Multivariate Cox model analysis indicated that age, sex, radiotherapy, chemotherapy, surgery, multiple primary tumors, marital status, and distant metastasis status are independent prognostic factors for CSS in patients with ATC, while for patients with PSCCTh, the corresponding factors are age, radiotherapy, multiple primary tumors, and surgery. The C-index values of the two models were both &gt; 0.8, indicating that the models exhibited good discriminative ability.ConclusionPrognostic factors influencing CSS were not identical in patients with ATC and PSCCTh. These findings indicate that different clinical treatment and management plans are required for patients with these two types of thyroid cancer.
Metabolic Surgery on Patients With Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis
Authors: Yue Wenwen , Huang Xin , Zhang Wenjing , Li Shumin , Liu Xu , Zhao Yian , Shu Jiaxin , Liu Teng , Li Weihua , Liu Shaozhuang 
Published: March 2022

Polycystic ovary syndrome (PCOS) is a complicated reproductive endocrine disease that is closely related to obesity. Metabolic surgery ameliorates a series of clinical manifestations and related comorbidities of PCOS. However, the overall efficacy of metabolic surgery on PCOS remains uncertain. This systematic review and meta-analysis aimed to evaluate the therapeutic effects of metabolic surgery on obese patients with PCOS. A systematic literature search for relevant studies was conducted on PubMed, Embase, Web of Science, and the Cochrane Library from inception to June 2021. Data extraction and quality evaluation were performed by three researchers, and RevMan 5.4 software was used to conduct the meta-analysis. A total of 14 studies involving 501 obese patients with PCOS were included. Incidence of PCOS in obese women ranged from 5.5% to 63.5% among the included studies. The results showed the incidence of abnormal menstruation decreased from 81% to 15% (OR=0.03, 95% confidence interval (CI): 0.01–0.08), while the incidence of hirsutism dropped from 71% to 38% (OR=0.21, 95% CI: 0.06–0.74). Serum total testosterone and free testosterone levels decreased by 25.92 ng/dL (MD = -25.92, 95% CI: -28.90– -22.93) and 2.28 ng/dL (SMD = -2.28, 95% CI: -3.67– -0.89), respectively. Sex hormone-binding globulin (SHBG) levels increased by 26.46 nmol/L (MD = 26.46, 95% CI: 12.97–39.95). Serum anti-Mullerian hormone (AMH) levels decreased by 1.29 ng/mL (MD = -1.29, 95% CI: -1.92– -0.66). Small sample size studies revealed that pregnancy rates ranged from 95.2% to 100% postoperatively. Metabolic surgery contributed to marked improvement of abnormal menstruation, hirsutism, and levels of free testosterone, total testosterone, SHBG, and AMH in patients with PCOS. Our findings indicate that patients with PCOS are expected to benefit from metabolic surgery, and could help potentially improve their reproductive outcomes. Metabolic surgery could thus be a new viable option for the clinical treatment of PCOS.Systematic Review RegistrationPROSPERO https://www.crd.york.ac.uk/PROSPERO/, identifier CRD42021251524.
Prediction of the Fundus Tessellation Severity With Machine Learning Methods
Authors: Shao Lei , Zhang Xiaomei , Hu Teng , Chen Yang , Zhang Chuan , Dong Li , Ling Saiguang , Dong Zhou , Zhou Wen Da , Zhang Rui Heng , Qin Lei , Wei Wen Bin 
Published: March 2022

PurposeTo predict the fundus tessellation (FT) severity with machine learning methods.MethodsA population-based cross-sectional study with 3,468 individuals (mean age of 64.6 ± 9.8 years) based on Beijing Eye Study 2011. Participants underwent detailed ophthalmic examinations including fundus images. Five machine learning methods including ordinal logistic regression, ordinal probit regression, ordinal log-gamma regression, ordinal forest and neural network were used.Main Outcome MeasureFT precision, recall, F1-score, weighted-average F1-score and AUC value.ResultsObserved from the in-sample fitting performance, the optimal model was ordinal forest, which had correct classification rate (precision) of 81.28%, while 34.75, 93.73, 70.03, and 24.82% in each classified group by FT severity. The AUC value was 0.7249. And the F1-score was 65.05%, weighted-average F1-score was 79.64% on the whole dataset. For out-of-sample prediction performance, the optimal model was ordinal logistic regression, which had precision of 77.12% on the validation dataset, while 19.57, 92.68, 64.74, and 6.76% in each classified group by FT severity. The AUC value was 0.7187. The classification accuracy of light FT group was the highest, while that of severe FT group was the lowest. And the F1-score was 54.46%, weighted-average F1-score was 74.19% on the whole dataset.ConclusionsThe ordinal forest and ordinal logistic regression model had the strong prediction in-sample and out-sample performance, respectively. The threshold ranges of the ordinal forest model for no FT and light, moderate, severe FT were [0, 0.3078], [0.3078, 0.3347], [0.3347, 0.4048], [0.4048, 1], respectively. Likewise, the threshold ranges of ordinal logistic regression model were ≤ 3.7389, [3.7389, 10.5053], [10.5053, 13.9323], &gt; 13.9323. These results can be applied to guide clinical fundus disease screening and FT severity assessment.
Efficacy and Safety of Cryobiopsy vs. Forceps Biopsy for Interstitial Lung Diseases, Lung Tumors, and Peripheral Pulmonary Lesions: An Updated Systematic Review and Meta-Analysis
Authors: Giri Mohan , Huang Guichuan , Puri Anju , Zhuang Rongjuan , Li Yishi , Guo Shuliang 
Published: March 2022

BackgroundCryobiopsy has emerged as a novel alternative to conventional forceps biopsy for the diagnosis of interstitial lung diseases (ILDs), lung tumors, and peripheral pulmonary lesions (PPLs). This study aims to compare cryobiopsy and forceps biopsy for the diagnosis of these lung pathologies with respect to efficacy and safety by performing a meta-analysis of updated evidence.MethodsA number of databases, such as PubMed, Embase, Web of Science, the Cochrane Library, OVID, CNKI, and Wanfang database, were searched for eligible studies. Randomized and non-randomized comparative studies investigating the efficacy and safety of cryobiopsy vs. forceps biopsy for lung pathologies were included. Pooled results were calculated as an odds ratio (OR) or standardized mean difference (SMD) with 95% CI.ResultsA total of 39 studies, such as 9 RCTs with 3,586 biopsies (1,759 cryobiopsies and 1,827 flexible forceps biopsies) were analyzed. Cryobiopsy was associated with a significant increase in the diagnostic rates of ILDs (OR, 4.29; 95% CI, 1.85–9.93; p &lt; 0.01), lung tumors (OR, 3.58; 95% CI, 2.60–4.93; p &lt; 0.01), and PPLs (OR, 1.70; 95% CI, 1.23–2.34; p &lt; 0.01). Cryobiopsy yielded significantly larger specimens compared with flexible forceps biopsy (SMD, 3.06; 95% CI, 2.37–3.74; p &lt; 0.01). The cryobiopsy group had a significantly higher (moderate to severe) bleeding risk than the forceps group (OR, 2.17; 95% CI, 1.48–3.19; p &lt; 0.01). No significant difference was observed in the incidence of pneumothorax between the groups (OR, 0.90; 95% CI, 0.44–1.85; p = 0.78).ConclusionOur results demonstrate that cryobiopsy is a safe and efficacious alternative to conventional forceps biopsy.