bluuebunny/crossref_metadata_2025_split huggingface dataset:
An overview of adsorptive desulfurization of liquid transportation fuels over various adsorbents including zeolites
Authors: Yeole Niteen R. 
Published: July 2022

AbstractThe conventional technique of hydrodesulfurization (HDS) faces challenges while removing refractory sulfur compounds from liquid fuels. Alternative techniques are under exploration. One of the alternative techniques is adsorptive desulfurization (ADS). In ADS, an adsorbent is used to remove sulfur through physical or chemical adsorption. Moreover, it is possible at ambient conditions. Recent developments in the area of ADS is the focus of the present review. Various adsorbents have been assessed for ADS of the model and real feedstocks. These include both activated carbons and zeolites. Their modification through incorporation of metal ions can improve the performance. Present paper reviews recent progress regarding the development of adsorbents. Improvement of selectivity and stability along with regeneration and reuse too, reviewed. Regeneration studies are helpful in knowing the reusability of adsorbents. Various methods of regeneration such as thermal, solvent and their combination have been addressed. Thus, present paper covers modification, testing, regeneration and reuse of adsorbents for ADS of liquid fuels. Equilibrium, kinetic and thermodynamic studies relevant to chosen topic also reviewed. Challenges do exist in testing adsorbents for ADS of commercial fuels. These challenges arise due to the competitive adsorption between sulfur compounds and aromatics. For commercialization of ADS, the development of adsorbent with cheaper metal ions and ideal regeneration methods are essential.
Optimization of photocatalytic degradation of biochemical oxygen demand from textile industry effluent using copper oxide nanoparticles by response surface methodology
Authors: Mohammadi Leili , Mohammadpour Amin , Hosseini Mohammad Reza , Shahsavani Ebrahim , Rayeni Reza Abbasi , Golaki Mohammad , Rahdar Abbas , Pandey Sadanand 
Published: July 2022

AbstractThis study aimed at photocatalytic degradation of biochemical oxygen demand (BOD) from the effluent of the Baluch textile factory in Iranshahr (Iran) using copper oxide nanoparticles (CuONPs). The characteristics of CuONPs were analyzed using a scanning electron microscope (SEM), transmission electron microscope (TEM), X‐ray diffraction (XRD) and X‐ray fluorescence (XRF). The results showed that the maximum removal efficiency (90.03%) was related to the state in which the intensity of ultraviolet (UV) was at the highest value (30 W). In this study, high values of coefficient of determination (R2) (99.2%) and adjusted coefficient of determination (adjusted R2) (98.11%) indicated that the very large share of changes in response variables was determined by independent factors. According to the results of analysis of variance, the order of the effect of the factors used in the study were as follows: pH > UV > time > Copper(II) oxide (CuO) dose. The BOD removal efficiency increased when pH was increased from 3 to 7 and contact time was increased from 10 to 60 min. More than 89% of BOD was removed at pH 7 and contact time 60 min. As such, when nanoparticle dose (from 0.02 to 0.05 g/L and contact time from 10 to 60 min) increased, so that the highest removal efficiency (89%) was reported at a dose of 0.05 g/L nanoparticles and a contact time of 60 min. In general, the Langmuir isotherm had a much better fit (R2 = 0.991) than the Freundlich (R2 = 0.9712) and Temkin (R2 = 0.7545) isotherms.
Challenges and advances of organic electrode materials for sustainable secondary batteries
Authors: Shi Ruijuan , Jiao Shilong , Yue Qianqian , Gu Guangqin , Zhang Kai , Zhao Yong 
Published: July 2022

AbstractOrganic electrode materials (OEMs) emerge as one of the most promising candidates for the next‐generation rechargeable batteries, mainly owing to their advantages of bountiful resources, high theoretical capacity, structural designability, and sustainability. However, OEMs usually suffer from poor electronic conductivity and unsatisfied stability in common organic electrolytes, ultimately leading to their deteriorating output capacity and inferior rate capability. Making clear of the issues from microscale to macroscale level is of great importance for the exploration of novel OEMs. Herein, the challenges and advanced strategies to boost the electrochemical performance of redox‐active OEMs for sustainable secondary batteries are systematically summarized. Particularly, the characterization technologies and computational methods to elucidate the complex redox reaction mechanisms and confirm the organic radical intermediates of OEMs have been introduced. Moreover, the structural design of OEMs‐based full cells and the outlook for OEMs are further presented. This review will shed light on the in‐depth understanding and development of OEMs for sustainable secondary batteries.
Investigation on compression and mildew of mixed and separated maize
Authors: Liu Chaosai , Chen Guixiang , Zhou Yang , Yue Longfei , Liu Wenlei 
Published: July 2022

AbstractThis study explores the influence of different segregation configurations on the creep behaviors and mildew of maize. An inexpensive and easy‐to‐use system was designed, and three configurations of maize kernels distribution, i.e., uniform mixing (Mdm), alternating distribution (Mda), and segregated state distribution (Mds), with wet basis moisture content of 22.9%, were compressed under vertical pressure of 200 kPa through a one‐dimensional oedometer. The compression and creep behaviors were investigated using the strain/settlement–time results, and aerobic plate counting (APC) was performed to study the effect of distribution configuration on the mildew effect. A finite‐element model was established to simulate the temperature variation caused by physical environmental factors, and the heat production by fungi was quantified using the difference in temperature between simulation and test. The results indicate that the three‐element Schiffman model can represent the creep behavior of the maize with different distribution configurations. The average temperature of Mdm, Mda, and Mds were 7.53%, 12.98%, and 14.76% higher than the average room temperature, respectively. The aerobic plate count of Mdm, Mda, and Mds were 1.0 × 105, 2.2 × 105, and 8.8 × 105 cfu g−1 stored for 150 h, respectively. In general, the temperature and APC in segregated maize bulk are higher than uniform grain. The effectiveness of the numerical model was verified, and the heat production by maize bulk fungi was quantified using the test and numerical temperature difference. The average heat was the least in Mdm with 2.8 × 106 J m−3, and Mda and Mds were 1.7 and 2 times more than Mdm. And the heat was related to the segregation configurations and agreed very well with the APC and temperature results.
Expert consensus on clinical trials of human xenotransplantation in China
Authors: Huang Jiefu ,   China Organ Transplantation Development Foundation
Published: July 2022

AbstractThe history of xenotransplantation started in the 19th century. After a few decades of investigation, significant breakthroughs and preclinical milestones have been achieved worldwide. With the recent transplantation of genetically modified porcine kidneys and heart into humans, these ground‐breaking achievements have attracted great attention worldwide, in the hope that xenotransplantation might alleviate or even solve the problem of organ shortage. On January 20, 2022, the China Organ Transplantation Development Foundation convened a symposium on “The History, Current Situation and Future of Human Xenotransplantation Clinical Trials,” where ways to promote the ethical and sustainable development of xenotransplantation in China were discussed among the participating experts. A formal consensus was reached as the product of the symposium, outlining the expert opinions on scientific, regulatory, and ethical issues of clinical trials of xenotransplantation in China.
Inhibition of lysyl oxidase‐like 2 overcomes adhesion‐dependent drug resistance in the collagen‐enriched liver cancer microenvironment
Authors: Gong Lanqi , Zhang Yu , Yang Yuma , Yan Qian , Ren Jifeng , Luo Jie , Tiu Yuen Chak , Fang Xiaona , Liu Beilei , Lam Raymond Hiu Wai , Lam Ka‐On , Lee Anne Wing‐Mui , Guan Xin‐Yuan 
Published: July 2022

Abstract
The tumor microenvironment (TME) is considered to be one of the vital mediators of tumor progression. Extracellular matrix (ECM), infiltrating immune cells, and stromal cells collectively constitute the complex ecosystem with varied biochemical and biophysical properties. The development of liver cancer is strongly tied with fibrosis and cirrhosis that alters the microenvironmental landscape, especially ECM composition. Enhanced deposition and cross‐linking of type I collagen are frequently detected in patients with liver cancer and have been shown to facilitate tumor growth and metastasis by epithelial‐to‐mesenchymal transition. However, information on the effect of collagen enrichment on drug resistance is lacking. Thus, the present study has comprehensively illustrated phenotypical and mechanistic changes in an in vitro mimicry of collagen‐enriched TME and revealed that collagen enrichment could induce 5‐fluorouracil (5FU) and sorafenib resistance in liver cancer cells through hypoxia‐induced up‐regulation of lysyl oxidase‐like 2 (LOXL2). LOXL2, an enzyme that facilitates collagen cross‐linking, enhances cell adhesion‐mediated drug resistance by activating the integrin alpha 5 (ITGA5)/focal adhesion kinase (FAK)/phosphoinositide 3‐kinase (PI3K)/rho‐associated kinase 1 (ROCK1) signaling axis. Conclusion: We demonstrated that inhibition of LOXL2 in a collagen‐enriched microenvironment synergistically promotes the efficacy of sorafenib and 5FU through deterioration of focal adhesion signaling. These findings have clinical implications for developing LOXL2‐targeted strategies in patients with chemoresistant liver cancer and especially for those patients with advanced fibrosis and cirrhosis.
Clinical phenotype of adult‐onset liver disease in patients with variants in ABCB4 , ABCB11 , and ATP8B1
Authors: Nayagam Jeremy S. , Foskett Pierre , Strautnieks Sandra , Agarwal Kosh , Miquel Rosa , Joshi Deepak , Thompson Richard J. 
Published: July 2022

Abstract
Variants in ATP8B1, ABCB11, and ABCB4 underlie the most prevalent forms of progressive familial intrahepatic cholestasis. We aim to describe variants in these genes in a cohort of patients with adult‐onset liver disease, and explore a genotype–phenotype correlation. Patients with onset of liver disease aged above 18 who underwent sequencing of cholestasis genes for clinical purposes over a 5‐year period were identified. Bioinformatic analysis of variants was performed. Liver histology was evaluated in patients with variants. Of the 356 patients tested, at least one variant was identified in 101 (28.4%): 46 ABCB4, 35 ABCB11, and 28 ATP8B1. Patients with ABCB4 variants had chronic liver disease (71.7%) and pregnancy‐associated liver dysfunction (75%), with a younger age of onset in more severe genotypes (p = 0.046). ABCB11 variants presented with pregnancy‐associated liver dysfunction (82.4%) and acute/episodic cholestasis (40%), with no association between age of onset and genotype severity. ATP8B1 variants were associated with chronic liver disease (75%); however, they were commonly seen in patients with an alternate etiology of liver disease and variants were of low predicted pathogenicity. In adults with suspected genetic cholestasis, variants in cholestasis genes were frequently identified and were likely to contribute to the development of liver disease, particularly ABCB4 and ABCB11. Variants were often in heterozygous state, and they should no longer be considered recessive Mendelian traits. Sequencing cholestasis genes in selected patients with adult‐onset disease should be considered, with interpretation in close collaboration with histopathologists and geneticists.
A novel automated depression detection technique using text transcript
Authors: Yadav Uma , Sharma Ashish K. 
Published: July 2022

AbstractDepression is one of the most common mental illnesses, impacting billions of people worldwide. The lack of existing resources is impeding the country's economic prosperity. As a result, new approaches for detecting and treating mental diseases as well as reaching out to individuals are required so that people can overcome their daily challenges and become more productive. An automated depression detection system can greatly aid in clinical findings and early treatment of depression. Automatic detection, like in a clinical interview can be derived from various modalities that include video, audio, and text. Among these modalities, audio characteristics are the most commonly researched while text elements are seldom investigated. In the light of the above, this paper proposes a novel automated depression identification approach based on linguistic material gathered from patient interviews. The focus is to enhance both the accuracy and efficiency of detection. The proposed approach is made up of two parts: a Bidirectional Gated Recurrent Unit (BGRU) network for dealing with linguistic information and a fully coupled network that integrates the model outputs to measure the depressed state. The proposed approach is validated using Distress Analysis Interview Corpus‐Wizard‐of‐Oz interviews dataset. To evaluate the performance precision, recall, and F1 score are computed using the proposed approach and then the comparative analysis is done with the existing approaches. The proposed approach yielded an F1 score of 0.92, indicating the existence of depression as well as the projected severity level. It is realized from the generated results that the proposed approach has outperformed the previous ones. The proposed approach can not only automatically assess the severity of depression but also enhances both the accuracy and efficiency of detection. The proposed approach indicates the feasibility of BGRU over Long Short Term Memory by achieving exceptional results for recognition of depression.
Naphthenic acid fraction components from oil sands process‐affected water from the Athabasca Oil Sands Region impair murine osteoblast differentiation and function
Authors: Gutgesell Robert M. , Jamshed Laiba , Frank Richard A. , Hewitt L. Mark , Thomas Philippe J. , Holloway Alison C. 
Published: July 2022

AbstractThe extraction of bitumen from surface mining in the Athabasca Oil Sands Region (AOSR) produces large quantities of oil sands process‐affected water (OSPW) that needs to be stored in settling basins near extraction sites. Chemical constituents of OSPW are known to impair bone health in some organisms, which can lead to increased fracture risk and lower reproductive fitness. Naphthenic acid fraction components (NAFCs) are thought to be among the most toxic class of compounds in OSPW; however, the effect of NAFCs on osteoblast development is largely unknown. In this study, we demonstrate that NAFCs from OSPW inhibit osteoblast differentiation and deposition of extracellular matrix, which is required for bone formation. Extracellular matrix deposition was inhibited in osteoblasts exposed to 12.5–125 mg/L of NAFC for 21 days. We also show that components within NAFCs inhibit the expression of gene markers of osteoblast differentiation and function, namely, alkaline phosphatase (Alp), osteocalcin, and collagen type 1 alpha 1 (Col1a1). These effects were partially mediated by the induction of glucocorticoid receptor (GR) activity; NAFC induces the expression of the GR activity marker genes Sgk1 (12.5 mg/L) and p85a (125 mg/L) and inhibits GR protein (125 mg/L) and Opg RNA (12.5 mg/L) expression. This study provides evidence that NAFC concentrations of 12.5 mg/L and above can directly act on osteoblasts to inhibit bone formation and suggests that NAFCs contain components that can act as GR agonists, which may have further endocrine disrupting effects on exposed wildlife.
Change in Morphological Features of Enlarged Subarachnoid Spaces Following Treatment in Idiopathic Normal Pressure Hydrocephalus
Authors: Camerucci Emanuele , Graff‐Radford Jonathan , Jones David T. , Elder Benjamin D. , Gunter Jeffrey L. , Cutsforth‐Gregory Jeremy K. , Botha Hugo , Murphy Matthew C. , Johnson Derek R. , Davidge‐Pitts Caroline , Jack Clifford R. , Huston John , Cogswell Petrice M. 
Published: July 2022

BackgroundFocally enlarged sulci (FES) are areas of proposed extraventricular fluid entrapment that may occur within idiopathic normal pressure hydrocephalus (iNPH) with radiographic evidence of disproportionately enlarged subarachnoid‐space hydrocephalus (DESH), and should be differentiated from atrophy.PurposeTo evaluate for change in FES size and pituitary height after shunt placement in iNPH.Study typeRetrospective.SubjectsA total of 125 iNPH patients who underwent shunt surgery and 40 age‐matched controls.Field Strength/Sequence1.5 T and 3 T. Axial T2w FLAIR, 3D T1w MPRAGE, 2D sagittal T1w.AssessmentFES were measured in three dimensions and volume was estimated by assuming an ellipsoid shape. Pituitary gland height was measured in the mid third of the gland in iNPH patients and controls.Statistical testsWilcoxon signed‐rank test for comparisons between MRI measurements; Wilcoxon rank sum test for comparison of cases/controls. Significance level was P < 0.05.ResultsFifty percent of the patients had FES. FES volume significantly decreased between the pre and first postshunt MRI by a median of 303 mm3 or 30.0%. Pituitary gland size significantly increased by 0.48 mm or 14.4%. FES decreased significantly by 190 mm3 or 23.1% and pituitary gland size increased significantly by 0.25 mm or 6% between the first and last postshunt MRI.Data ConclusionDecrease in size of FES after shunt placement provides further evidence that these regions are due to disordered cerebrospinal fluid (CSF) dynamics and should not be misinterpreted as atrophy. A relatively smaller pituitary gland in iNPH patients that normalizes after shunt is a less‐well recognized feature of altered CSF dynamics.Evidence Level3Technical EfficacyStage 2
Evaluation on the effect of ice glazing with different compound additives on the quality of frozen stored (−23 °C) large yellow croaker (Pseudosciaena crocea)
Authors: Chu Yuanming , Ding Zhaoyang , Yang Dazhang , Xie Jing 
Published: July 2022

AbstractBACKGROUNDCompounded ice glazing has been used in large yellow croaker to improve its quality during frozen storage. The ice glazing liquid is prepared by compound use of trehalose and tea polyphenols, and the moisture, protein‐related properties and freshness of the fish have been evaluated during 300 days of frozen storage.RESULTSThe results showed that the addition of trehalose effectively reduced the loss of water. At the same time, it was difficult for ice crystals to grow under the action of trehalose, the average diameter could still be maintained at 111.25–119.85 μm. The combination with tea polyphenols could effectively maintain the protein structure and keep the total volatile base nitrogen (TVB‐N) and K value within 11.84 mg/100 g and 13.18%, so that the freshness of the fish was always at the first level.CONCLUSIONIn a word, the ice glazing with 5% trehalose and 8% tea polyphenols had the best preservation effect, which was recommended for the frozen storage. © 2022 Society of Chemical Industry.
Co‐authoring with undergraduate students: An emerging process from the semi‐periphery of the world of science
Authors: Plakhotnik Maria S. 
Published: July 2022

AbstractUndergraduate students benefit from writing for publication and co‐authoring with faculty, who in turn find value in collaborating with students. Yet, compared to graduate students and novice researchers, undergraduates are rarely in the focus of research and practice around scholarly writing and co‐authorship. Furthermore, this limited knowledge is primarily, if not exclusively, produced by scholars in countries that dominate the international publication landscape. How faculty and undergraduates from countries in the semi‐periphery of the world of science collaborate to co‐author scholarly publications is not clear. This paper describes a process that has led to publishing articles with undergraduate students in the semi‐periphery in English language journals indexed in Web of Science (SSCI), Scopus, and the AJG guide. The process consists of two phases that differ across such dimensions as goals, length, key steps, and contributors' roles. The process demonstrates that collaboration with talented undergraduates is not different from co‐authoring with novice and experienced scholars in its final outcome, a high‐quality article, and its process of creative ideation, rigorous execution, and collective contribution. I discuss how journal editors, universities, and other researchers in the semi‐periphery could change the ways in which they approach publication collaborations with undergraduate students.
The barriers and informational needs of students and junior researchers when reading scientific papers
Authors: Wang Xiaoguang , Xia Lingying , Duan Qingyu 
Published: July 2022

AbstractStudents and junior researchers are important stakeholders in scholarly publishing, but there is relatively little research into their reading needs and barriers. This study hoped to understand the similarities and differences between junior researchers and students, between this group and more senior researchers and between different disciplines. The research comprised two parts: initial interviews to ascertain the main barrier and needs items, followed by a large‐scale online survey. The survey received 673 responses from Chinese students and junior researchers. The survey revealed that poor presentation leading to poor understanding was a common barrier, but there were disciplinary differences, with humanities scholars having fewer barriers than other disciplines. Postgraduates reported more barriers than undergraduates, and also scored information needs more highly. The results identify needed improvements in the presentation of articles and explanation of terminology in order to better engage with students and junior researchers.
Nurturing an ‘ethic of collaboration’: Dispatches from a case study on Jindal Global Law Review
Authors: Pagedar Aishwarya , Sanghi Sanskriti , Gangwar Shivangi 
Published: July 2022

Key points
Building an ethos of trust and respect is a key factor in the success of engaging early career researchers (ECRs) in editorial teams.
Regular meetings and open communication ensure accountability and sharing of responsibilities.
Nurturing and sustaining an ethic of collaboration with senior editors mentoring junior ones ensures a strong allegiance and sense of responsibility to the journal.
Being part of a journal editorial group can help build community and solidarity with other researchers which may not be so easily achieved within academia.
Real‐time engagement, whilst beneficial to the journal and to authors, may be too onerous for ECRs and separation of work and personal life should be maintained.