bluuebunny/crossref_metadata_2025_split huggingface dataset:
A unique mineralizing pool of Gli1+ stem cells builds the tendon enthesis and demonstrates therapeutic potential
Authors: Fang Fei , Xiao Yang , Zelzer Elazar , Leong Kam W. , Thomopoulos Stavros 
Published: February 2022

SummaryThe enthesis, a fibrocartilaginous transition between tendon and bone, is necessary for the transfer of force from muscle to bone to produce joint motion. The enthesis is prone to injury due to mechanical demands, and it cannot regenerate. A better understanding of how the enthesis develops will lead to more effective therapies to prevent pathology and promote regeneration. Here, we used single-cell RNA sequencing to define the development transcriptome of the entheses over postnatal stages. Six resident cell types, including enthesis progenitors and mineralizing chondrocytes, were identified along with their transcription factor regulons and temporal regulation. Following our prior discovery of the necessity of Gli1-lineage cells for enthesis development and healing, we then examined their transcriptomes at single cell resolution and demonstrated their clonogenicity and multipotency. Transplantation of these Gli1- lineage cells to enthesis injuries improved healing, demonstrating their therapeutic potential for enthesis regeneration.HighlightsThe transcriptome and differentiation trajectory of enthesis stem cells during postnatal development are defined at single cell resolution.Transcription factor regulons drive enthesis stem cell differentiation.Gli1-lineage enthesis stem cells demonstrate in vivo and in vitro clonogenicity and multipotency.Transplantation of Gli1-lineage enthesis stem cells to enthesis injuries improves healing.
Reflections on the impact of informal sector tourism on indigenous Namibian Craft processes
Authors: Beamer Becky , Gleason Kimberly C. 
Published: February 2022

Purpose The purpose of this study is to use a spreadable form of creative expression, bookwork, to illustrate the encroachment upon the indigenous craft process of Namibian master crafters. In addition, the authors hope to inspire a dialogue regarding the value of interdisciplinary research between the arts and business and promote creative expression as scholarly output that can provide additional depth to research topics in business.Design/methodology/approach This study introduces bookwork as a research technique used to convey insights regarding the consequences to master crafters and indigenous craft practices arising from the economic activities of informal sector tourists as “outsiders” – those external to the indigenous Namibian Craft community.Findings In this paper, the authors convey the manner in which outsiders (such as tourists) permanently influence the traditional craft culture of indigenous communities in a largely unexplored cultural ecological niche in Namibia by purchasing low cost, easily mass produced, yet inauthentic brightly colored objects. It is likely that craft processes designed for revenue generation will encroach on the role of the master crafters in Namibian society and permanently redirect creative activities away from the indigenous practices.Research limitations/implications The researchers acknowledge the biases they have, as outsiders, in their perception of Namibian master crafters and craft practices.Social implications The human capital of the master crafters of Namibia is being eroded and traditional craft practices are being distorted due to incentives created by tourist preferences for cheap, inauthentic replicas of the master crafters’ work.Originality/value While some business disciplines, such as marketing, have incorporated the arts into their research, the use of creative expression in many business disciplines has been limited. The authors are the first to use bookwork to explore academic business research questions as per their knowledge. In addition, this study provides a new perspective, that of the outsider, in assessing how tourism impacts traditional Namibian Craft processes.
Dispatch information affects diagnosis in paramedics: an experimental study of applied dual-process theory
Authors: Keene Toby , Pammer Kristen , Lord Bill , Shipp Carol 
Published: February 2022

PurposePrevious research has shown that paramedics form intuitive impressions based on limited “pre-arrival” dispatch information and this subsequently affects their diagnosis. However, this observation has never been experimentally studied.Design/methodology/approachThis was an experimental study of 83 Australian undergraduate paramedics and 65 Australian paramedics with median 14 years' experience (Range: 1–32 years). Participants responded to written vignettes in two parts that aimed to induce an intuitive impression by placing participants under time pressure and with a secondary task, followed by a diagnosis made without distraction or time pressure. The vignettes varied the likelihood of Acute Coronary Syndrome (ACS) and measured self-reports of typicality and confidence. Answer fluency, which is the ease with which the answer comes to mind, was also measured.FindingsMore participants exposed to the likely pre-arrival vignette recorded a final diagnosis of ACS, than those exposed to unlikely pre-arrival information (0.85 [95%CI: 0.78, 0.90] vs 0.74 [95%CI: 0.66, 0.81]; p = 0.03). This effect was greater in paramedics with more than 14 years' experience (0.94 [95%CI: 0.78, 0.99] vs 0.67 [95%CI: 0.48, 0.81]; p = 0.01). Answer fluency and confidence were associated with the impression, while the impression and confidence were associated with final diagnosis.Practical implicationsThe authors have experimentally shown that pre-arrival information can affect subsequent diagnosis. The most experienced paramedics were more likely to be affected.Originality/valueThis is the first experimental study of diagnostic decision-making in paramedics and paramedic students.
A conceptual analysis of the ethicality of Web-based messaging on the COVID-19 pandemic
Authors: Joseph Rhoda C. , Ali Mohammad 
Published: February 2022

Purpose
The purpose of this study is to examine the primary sources and methods of Web-based messaging during the early stages of the coronavirus pandemic. The authors use ethical lens to develop a conceptual framework to inform and reduce conflicts of Web-based messaging associated with COVID-19.

Design/methodology/approach
This paper provides a comprehensive review of three different ethical schools and identifies the cohesive theme of common good across them. Common good leading to a greater good serves as the overarching ethical construct for Web-based messages that focus on society and not the singular individual, business or political ideology.

Findings
The findings suggest that the ethical construct of common good focuses on prioritizing the society over the individual and draws upon utilitarian principles focused on consequences, Kantian principles focused on intentions and Aristotelian principles focused on the definition of good. Web-based messaging on COVID-19 originates from diverse public and private sources and ethically can be governed by adherence to achieving the greatest good for society. Pervasive conflicts with COVID-19 messaging can be mitigated by pursuing a more ethical agenda with messages.

Originality/value
This manuscript provides a conceptual framework, based on ethical principles, to serve as a blueprint for Web-based messaging during a pandemic. This work offers an ethical perspective for communication during a pandemic and it is original in conceptualizing the components of Web-based messaging and decomposing them into the different levels where conflicts can occur. This article can serve as a template for Web-based communication pertaining to future pandemics and other events that benefit from prioritizing the impact on society over the impact on the individual.
An assessment of the impact of professional development and training on job performance of library staff in Federal University Oye Ekiti libraries, Nigeria
Authors: Osiesi Mensah Prince , Odobe Victor Tobiloba , Sanni Kamorudeen Taiwo , Adams Adijat Bolanle , Oke Chigozie Celestina , Omokhabi Udukhomose Suleiman , Okorie Nnaemeka Chijioke 
Published: February 2022

PurposeThe purpose of this paper is to assess the impact of professional training and development for librarians/library staff in the southwest, Nigeria; especially the Federal University of OyeEkiti, Nigeria. Thus, this study intends to assess the impact of staff professional development and training on the job performance of library staff in the Federal University Oye Ekiti, Nigeria.Design/methodology/approachThe descriptive survey research design was used in carrying out this study. The population of study cuts across all library staff/attendants in the Federal University Oye Ekiti departmental, faculty and the university libraries. The purposive sampling technique was used in selecting the sample for the study (77 library staff). Research instruments, developed by the researchers, Staff Development Programme Questionnaire (r = 0.79), Staff performance Questionnaire (r = 0.81), Challenges of Staff Professional Development and Training Questionnaire (r = 0.82), were used for data collection. The data were analysed using descriptive statistics (frequency counts and percentages, mean and standard deviation) and inference statistics (correlation and one-way ANOVA) at a 5% level of significance.FindingsResults revealed that the level of the job performance of library staff in Federal University Oye-Ekiti (FUOYE) is high; there is a positive and statistically significant relationship between the professional development of library staff and their performance in the job; professional development and training of library staff significantly impact their job performance; orientation, in-house training, seminars, on-the-job training and instructor-led training.Research limitations/implicationsThe study was limited to the university libraries in the Federal University Oye Ekiti, Nigeria. The variables used in this study were restricted to training and development of library staff and job performance of librarians in FUOYE, and professional development programmes available for FUOYE librarians.Practical implicationsOther forms of professional development programmes such as Distance Educational Programmes, Conferences/Workshops, Study visits, Formal professional library education and TETFUND Programmes should be made available for university library staff. Universities should always organise staff professional development programmes; since it enhances the job performance of library staff.Originality/valueThis article is original and has not been published elsewhere.
Can personality traits influence Brazilian university students' financial literacy?
Authors: Goulart Marco Antonio de Oliveira Vieira , da Costa Jr Newton Carneiro Affonso , Paraboni Ana Luiza , Luna Mônica Maria Mendes 
Published: February 2022

PurposeThe objective of the present study is to assess the financial literacy levels of students at a Brazilian university and investigate how these levels are affected by profile characteristics and personality traits.Design/methodology/approachData were collected using SurveyMonkey, and a link to the questionnaire was sent by e-mail. The questionnaire contains three blocks of questions: demographics, financial literacy and personality traits. Ordered logistic regression was applied to a sample of 1,312 students.FindingsYounger participants, those with higher incomes and men were more likely to have a high level of financial literacy. The same was true of those who were less extrovert, i.e. assertive, sociable, optimistic and communicative students. These results contribute to the field by indicating which population segments should be prioritized in efforts to promote financial literacy.Originality/valueTo the best of our knowledge, no study has compared Financial Literacy and Personality Traits in Brazil, a developing country that is only beginning to develop national financial literacy strategies.
Dissecting the stock to flow model for Bitcoin
Authors: Morillon Thibaut G. , Chacon Ryan G. 
Published: February 2022

Purpose
Perhaps the most popular pricing model among Bitcoin enthusiasts is the stock-to-flow (S2F) model. The model gained significant traction after successfully predicting the meteoric rise of Bitcoin prices from late 2020 to early 2021. This paper dissects the S2F model for Bitcoin empirically to determine its viability and investigate whether investors can profit from an S2F-based trading strategy.

Design/methodology/approach
This paper, dissects the S2F model for Bitcoin by putting it through a battery of tests to examine its design, characteristics, robustness and appropriateness.

Findings
Overall, this paper finds the S2F model to be insensitive to differing assumptions in the early stages of the model, alleviating concerns about data mining. This paper produces a dynamic S2F model with no peek-ahead bias and shows evidence that prediction accuracy increases over time. Finally, this paper shows that a dynamic trading strategy that goes long (short) when Bitcoin is undervalued (overvalued) according to S2F is far less profitable than a classic buy-and-hold strategy.

Originality/value
To the best of the authors’ knowledge, this is the first paper to analyze the S2F model in an academic setting by providing a rigorous assessment of the model's construction. This paper demonstrates how the model can be implemented realistically without the peek-ahead bias, creating a tool that can be used contemporaneously by investors.
Weight discrimination: implications to the workplace
Authors: Gaines Rachel , Vincent Vinod 
Published: February 2022

Purpose
Given the prevalence of obesity in society at large and ensuing weight discrimination in the workplace, the purpose of this paper is to bring to light the social stigma attached to obesity, stimulate the discussion around enacting better legislation to alleviate weight-based discrimination in the workplace and highlight the role of human resource (HR) departments in preventing such discriminatory actions.

Design/methodology/approach
This paper reviews current perceptions, trends, laws and consequences related to obesity and weight discrimination and discusses the implications for organizations and HR professionals.

Findings
Weight discrimination is a real problem in society as a whole and workplaces in particular. HR professionals have a key role to play in removing weight discrimination and creating a more inclusive and equitable workplace.

Originality/value
Although weight discrimination has significant professional and personal consequences, there is a lack of explicit laws and policies that provide strong protection to impacted individuals. This paper brings the issue to light and discusses the role of HR in eliminating such bias and discriminatory practices in the workplace.
What makes a smart village smart? A review of the literature
Authors: Gerli Paolo , Navio Marco Julio , Whalley Jason 
Published: February 2022

Purpose
Smart villages (SVs) have lately attracted considerable attention, but what does the term mean? This literature review aims to explore its ambiguous nature and to identify main theoretical and practical aspects to be further explored in the conceptualisation and implementation of these initiatives.

Design/methodology/approach
The analysis draws upon a review of 79 references from the grey and academic literature on SVs, identified through a systematic search of academic databases and snowball sampling.

Findings
This review highlights how the definition and characterisation of SVs is currently shaped by disciplinary backgrounds and geographical contexts. SVs are often viewed as the rural version of smart cities or an innovative model for rural development, but there has been little engagement in the literature with other debates around rurality and sustainable development. It is only through engaging with these other debates that a better understanding of the term will emerge.

Originality/value
To the best of the authors’ knowledge, this is the first paper to conduct a systematic review on SVs. In addition to identifying the main trends in the conceptualisations and design of these initiatives, this paper contributes to the academic debate on smart rural development and provides useful recommendations to both policy makers and practitioners.
Surgical procedures and innovative approaches for vitiligo regenerative treatment and melanocytorrhagy
Authors: Kawakami Tamihiro 
Published: February 2022

AbstractSurgical treatments for vitiligo are a safe and effective treatment modality for select patients with vitiligo. Many techniques of vitiligo surgery exist, each with unique advantages and disadvantages. We reviewed the various surgical therapies and innovative approaches for vitiligo regenerative treatment reported in the literature. Surgical therapies can be subdivided into tissue grafting methods and cellular grafting methods. Tissue grafting methods mainly include mini punch grafts, suction blister roof grafts, and hair follicle grafts. Cellular grafting methods include cultured and non‐cultured treatments. The efficacy needs to be improved largely due to the poor proliferation and quality of the autologous melanocytes. Rho‐associated protein kinase inhibitor enhances primary melanocyte culture proliferation from vitiligo patients to prevent apoptosis. Innovative approaches using stem cell methods could prove invaluable in developing a novel cell therapy for patients suffering from vitiligo. We succeeded in inducing melanin pigmentation in mice skin in vivo using our human induced pluripotent stem cell‐derived melanocytes. In addition, we reviewed melanocytorrhagy, detachment and transepidermal loss of melanocytes, and melanocyte‐related adhesion molecules. These adhesion molecules include epithelial cadherin, discoidin domain receptor tyrosine kinase 1, glycoprotein non‐metastatic melanoma protein B, macrophage migration inhibiting factor, 17β‐hydroxysteroid dehydrogenase 1, and E26 transformation‐specific 1.
Novel synergistic freezing methods and technologies for enhanced food product quality: A critical review
Authors: Hu Rui , Zhang Min , Liu Wenchao , Mujumdar Arun S. , Bai Baosong 
Published: February 2022

AbstractFreezing has a long history as an effective food preservation method, but traditional freezing technologies have quality limitations, such as the potential for water loss and/or shrinkage and/or nutrient loss, etc. in the frozen products. Due to enhanced quality preservation and simpler thawing operation, synergistic technologies for freezing are emerging as the optimal methods for frozen food processing. This article comprehensively reviewed the recently developed synergistic technologies for freezing and pretreatment, for example, ultrasonication, cell alive system freezing, glass transition temperature regulation, high pressure freezing, pulsed electric field pretreatment, osmotic pretreatment, and antifreeze protein pretreatment, etc. The mechanisms and applications of these techniques are outlined briefly here. Though the application of new treatments in freezing is relatively mature, reducing the energy consumption in the application of these new technologies is a key issue for future research. It is also necessary to consider scale‐up issues involved in large‐scale applications as much of the research effort so far is limited to laboratory or pilot scale. For future development, intelligent freezing should be given more attention. Freezing should automatically identify and respond to different freezing conditions according to the nature of different materials to achieve more efficient freezing.Practical ApplicationThis paper provides a reference for subsequent production and research, and analyzes the advantages and disadvantages of different novel synergistic technologies, which points out the direction for subsequent industry development and research. At the same time, it provides new ideas for the freezing industry.
Endogenous carbon monoxide due to hemolytic anemia: A forensic red herring
Authors: Hyson Brian E. , Wehbie Robert S. , Haikal Nabila A. , Bishop‐Freeman Sandra C. 
Published: February 2022

AbstractCarbon monoxide (CO) toxicity associated with exposure to an environmental, exogenous source, is routinely investigated in the field of forensics. Paramedics responded to the home of a 60‐year‐old woman who complained of persistent nausea, dizziness, and fatigue. Her initial carboxyhemoglobin (COHb) saturation was 25% as measured by paramedics in the field via pulse CO‐oximetry (SpCO) and was, 2 hours later, confirmed by hospital laboratory spectrophotometric analysis to be 16% after initial treatment in the emergency department. The clinical presentation of environmental CO exposure and subsequent death notification to the North Carolina Office of the Chief Medical Examiner prompted an extensive investigation into the suspected residential source of CO, which ultimately ruled out all exogenous sources. The medicolegal death investigator later discovered an updated hematology consultation note, which determined the actual source of the CO to be endogenously produced from disease. Herein, we report an unusual fatality involving enhanced endogenous CO production caused by warm autoimmune hemolytic anemia. This unique case report and brief literature review of disease‐related elevation of endogenous CO will shed light on this lesser‐known phenomenon alerting the forensic community to its potential occurrence and need for consideration when sources of environmental exposure have been exhausted.
Identity in Diversity: Programmatic Pictures of the Enlightenment
Authors: Fulda Daniel 
Published: February 2022

AbstractInquiries into the realm of Enlightenment identities usually depart from the texts of this period. Yet pictures created by contemporary artists are equally crucial and largely overlooked sources that have the potential to condense such identities. Using examples from late eighteenth‐century France and early eighteenth‐century Germany, this paper shows how pictures were used to propagate agendas of enlightenment and, sometimes, to draft it in the first place. It discusses how different ideas of enlightenment connected to different strategies of visual representation and to schemes of public usage of the pictures.
Les passeurs et passeuses littéraires dans le discours identitaire en Pologne des Lumières
Authors: Bajer Michał 
Published: February 2022

AbstractThere are three ways of conceptualising the identity of men and women involved in the circulation of literary forms and foreign texts developed in Poland during the Enlightenment era: firstly, the identity of men and women of letters as members of the privileged social classes; secondly, their identity as members of a cosmopolitan community; thirdly, their involvement in the emerging idea of nationhood. This article explores the relationship between these three aspects, particularly focusing on the ways in which notions of identity are expressed in texts which explicitly discuss the question of cultural transfer.