bluuebunny/crossref_metadata_2025_split huggingface dataset:
Top management team heterogeneity and economic performance: a micro-foundations perspective of academic business venturing
Authors: Sciarelli Mauro , Landi Giovanni C. , Turriziani Lorenzo , Prisco Anna 
Published: April 2022

PurposeThis research focuses on the relationship between Top Management Team heterogeneity (TMT) and University Spin-Offs (USOs) economic performance according to a micro-foundational perspective. The purpose consists in exploring whether a high academic representation in TMTs may improve USOs’ performance and how their competencies and backgrounds affect USOs’ economic success.Design/methodology/approachThe authors employed data from the Italian platform Netval to identify the entire population of USOs in southern Italy. They selected both pure and hybrid spin-offs that had at least one academic member on the TMT. Applying these conditions to our sample selection, the authors came to a population of 136 firms. They applied a hierarchical regression analysis to test the hypotheses.FindingsOur main findings reveal that the USOs’ economic performance improves with more academicians in the TMT and even in the same scientific field. Our data also shows that CEO duality has a negative impact on economic performance.Originality/valueThis work takes for the first time a micro-foundational perspective to analyze individual-level factors that affect USOs’ performance. The authors tried to bridge a research gap in the USO literature, shedding light on the relationship between TMT composition and new venture performance, considering some significant interactions between team members. Our expected findings also contribute to the general literature on entrepreneurial teams in new ventures and suggest a means to reconcile some inconsistent literature results on TMT heterogeneity and USO performance.
Perceived quality: in search of a definition
Authors: Solin Andrey , Curry Adrienne 
Published: April 2022

PurposeThis paper aims to present a review of extant literature representing attempts to define perceived quality and to propose a new definition. Perceived quality (PQ) is a well-researched, yet vaguely defined subject. Despite a plethora of PQ definitions suggested by various scholars, there is no consensus among researchers on what it really is. The main purpose of this study is to offer a conceptualization of PQ that different researchers and practitioners would agree upon.Design/methodology/approachThis study adopted Garvin's five approaches to defining quality as a frame of reference. The paper utilizes a continuum of approaches to underscore the fact that PQ is neither totally subjective nor wholly objective. After a comprehensive analysis of available conceptualizations, the paper then proposes a new definition that captures the intricate nature of PQ and aligns its various perspectives.FindingsThe paper proposes a new definition of PQ as an impression of quality. Such a conceptualization of PQ aligns the various researcher perspectives of it. It also highlights the fact that PQ relies on quality cues under conditions of limited product knowledge by the consumer, a situation known as information asymmetry.Originality/valueThe study contributes to the understanding of the elusive concept of PQ by suggesting a new definition of PQ.
Brexit and the United Kingdom's Devolutionary Constitution
Authors: Masterman Roger 
Published: April 2022

AbstractThis piece considers the implications of the Brexit process for the United Kingdom's territorial constitution. It advances two narratives of the devolutionary settlement; one which emphasises the continuing post‐devolution influence – and dominance – of the institutions of UK‐level government, the other which regards devolution as having engineered a quasi‐federal division of powers and having diluted the sovereignty of the Westminster Parliament via expressions of national sovereignty in Scotland, Wales and Northern Ireland. The continuing resonance of the former is addressed across three elements of the Brexit process: (1) the design and outcome of the 2016 referendum; (2) litigation concerning Brexit and devolution; and (3) the legislative process of repatriating competences to domestic institutions from the EU. Seen through these lenses, Brexit is argued to provide ongoing evidence of the democratic deficits that the post‐1998 phase of devolution was designed to address, and of an increasingly unstable territorial constitution.
Beyond 1973: UK Accession and the Origins of EC Consumer Policy
Authors: Leucht Brigitte 
Published: April 2022

AbstractThis article examines the role of the accession of the UK in the development of the European Community's consumer policy. It will show that British accession boosted the development of EC consumer policy by influencing the European Commission's 1975 programme for consumer and information policy and by providing the Commission with political legitimation for developing its new consumer policy. Beyond accession in 1973, British membership in the EC contributed to the eventual prioritisation of an economic model of European consumer citizenship over competing approaches that favoured consumer protection in the EC from a social policy rationale. This historical examination reveals long term tensions between the UK’s preference for market liberalisation and the creation of the common market, on the one hand, and attempts to safeguard national regulation, on the other – tensions which would resonate throughout the UK's membership of the EC/EU and beyond the area of consumer protection.
Informing adaptive forest management: A hazard rating tool for southern pine beetleDendroctonus frontalisin pitch pine barrens
Authors: Jamison Elizabeth‐Ann K. , D'Amato Anthony W. , Dodds Kevin J. 
Published: April 2022

AbstractClimate change is facilitating a novel range expansion of southern pine beetle (SPB) into globally rare north‐eastern pitch pine barrens.By assessing stand conditions present in SPB‐infested and uninfested pitch pine stands on Long Island, NY, USA, we developed a regionally‐calibrated hazard rating model that predicts stand‐level SPB susceptibility.The model indicates that a stand's SPB susceptibility increases with (1) increasing pitch pine basal area, (2) increasing instances of previous year SPB spots nearby, and (3) sandy soil texture.The model informs adaptation strategies to a novel pest dynamic by supporting the identification and prioritization of high hazard stands for prevention management.An alignment between treatments effective in reducing SPB vulnerability and conserving pine barrens communities indicates that pine barrens can be managed both to improve resilience to future threats and preserve historic ecological conditions.
Recycling and the material science tetrahedron: Everyday strategies of making in high temperature technologies of Iron Age southern Africa
Authors: Chirikure Shadreck 
Published: April 2022

AbstractThis paper applies the Material Science Tetrahedron concept to explore practices of pottery recycling in selected craft activities performed in first and second millennium CE southern Africa. It combines analyses of pottery decorative style on vessels and their fragments used for metal processing with fabric inclusion mineralogy and chemical composition to show that recycling was a sociotechnical endeavour integral to making and remaking everyday things in society. Recycling weaved, along the chaîne opératoire, tapestries of materialities formed by and flowing from relationships between crafting, materials, containers, and humans as part of daily routines of making, provisioning, and consumption.
Party‐led innovation of state‐sponsored intermediary organizations in Beijing, Shanghai, and Guangdong of China: Effects and managerial strategies
Authors: Li Wei 
Published: April 2022

AbstractAlthough it has become popular for the state in different regions to encourage social organizations (SOs) via innovation, few studies have examined the innovation of intermediary organizations (IOs) as an important mechanism in social governance reform. This article is a study of party‐led innovation of state‐sponsored IOs in three cities in China—Beijing, Shanghai, and Guangdong—particularly, the contexts, goals, and effects of the innovation. It finds that state‐sponsored IOs can gain organizational independence and managerial autonomy even though they receive a high level of financial resources from the state and carry out party activities. The innovation, aiming at supporting, leading, and regulating SOs, has enabled the state‐sponsored IOs to adopt less coercive network‐ and market‐based strategies than the hierarchical strategy to embed constituent SOs in the party's policy and organizational networks.
A national service for delivering CD19 CAR‐Tin large B‐cell lymphoma – The UK real‐world experience
Authors: Kuhnl Andrea , Roddie Claire , Kirkwood Amy A. , Tholouli Eleni , Menne Tobias , Patel Amit , Besley Caroline , Chaganti Sridhar , Sanderson Robin , O'Reilly Maeve , Norman Jane , Osborne Wendy , Bloor Adrian , Lugthart Sanne , Malladi Ram , Patten Piers E. M. , Neill Lorna , Martinez‐Cibrian Nuria , Kennedy Hannah , Phillips Elizabeth H. , Jones Ceri , Sharplin Kirsty , El‐Sharkawi Dima , Latif Anne‐Louise , Mathew Amrith , Uttenthal Benjamin , Stewart Orla , Marzolini Maria A. V. , Townsend William , Cwynarski Kate , Ardeshna Kirit , Ardavan Arzhang , Robinson Kate , Pagliuca Antonio , Collins Graham P. , Johnson Roderick , McMillan Andrew 
Published: April 2022

SummaryCD19 CAR‐T have emerged as a new standard treatment for relapsed/refractory (r/r) large B‐cell lymphoma (LBCL). CAR‐T real‐world (RW) outcomes published to date suggest significant variability across countries. We provide results of a large national cohort of patients intended to be treated with CAR‐T in the UK. Consecutive patients with r/r LBCL approved for CAR‐T by the National CAR‐T Clinical Panel between December 2018 and November 2020 across all UK CAR‐T centres were included. 404/432 patients were approved [292 axicabtagene ciloleucel (axi‐cel), 112 tisagenlecleucel (tisa‐cel)], 300 (74%) received the cells. 110/300 (38.3%) patients achieved complete remission (CR) at 6 months (m). The overall response rate was 77% (52% CR) for axi‐cel, 57% (44% CR) for tisa‐cel. The 12‐month progression‐free survival was 41.8% (axi‐cel) and 27.4% (tisa‐cel). Median overall survival for the intention‐to‐treat population was 10.5 m, 16.2 m for infused patients. The incidence of grade ≥3 cytokine release syndrome and neurotoxicity were 7.6%/19.6% for axi‐cel and 7.9%/3.9% for tisa‐cel. This prospective RW population of CAR‐T eligible patients offers important insights into the clinical benefit of CD19 CAR‐T in LBCL in daily practice. Our results confirm long‐term efficacy in patients receiving treatment similar to the pivotal trials, but highlight the significance of early CAR‐T failure.
Interventions for obstructive uropathy in advanced prostate cancer: a population‐based study
Authors: Nathan Arjun , Morris Melanie , Parry Matthew G. , Berry Brendan , Sujenthiran Arunan , Nossiter Julie , Payne Heather , Van Der Meulen Jan , Clarke Noel W. , Green James S. A. 
Published: April 2022

ObjectivesTo develop and validate a coding framework to identify interventions for upper tract obstructive uropathy (UTOU) in men with locally advanced and metastatic prostate cancer (PCa) using administrative hospital data to assess clinical outcomes. There are no population‐based studies on the incidence, treatment, and outcomes of this complication.Patients and MethodsPatients newly diagnosed with PCa between April 2014 and March 2019 were identified in the English cancer registry. A coding framework based on procedure (Office of Population Censuses and Surveys Classification of Surgical Operations and Procedures fourth edition) and diagnostic (International Classification of Diseases, 10th edition) codes was developed and validated. Subsequent clinical outcomes were determined using Hospital Episodes Statistics to determine the utility of the intervention.ResultsA total of 77 010 patients newly diagnosed with locally advanced, and 30 083 patients with metastatic PCa were identified. Of these, 1951 (1.8%) patients underwent an intervention for UTOU according to our coding framework: 830 (42.5%) had locally advanced disease and 1121 (57.5%) had metastatic disease. In all, 844 (43.3%) had a percutaneous nephrostomy (PCN), 473 (24.2%) had a PCN with antegrade stent, and 634 (32.5%) had a retrograde stent. The mean follow‐up was 43.2 months. The cumulative incidence of the use of these interventions at 1, 3, and 5 years was 2.5%, 3.6% and 4.2% in men with metastases compared to 0.5%, 0.9% and 1.4% in men with locally advanced disease.ConclusionA new coding framework, developed to identify procedures for UTOU was applied in the largest study to date of UTOU in men with primary locally advanced and metastatic PCa. Results demonstrated that 2% of men with locally advanced PCa and 4% of men with metastatic PCa require an intervention to resolve UTOU within 5 years of their PCa diagnosis.
Late Quaternary mud‐dominated, basin‐floor sedimentation of the Gulf of Corinth, Greece: Implications for deep‐water depositional processes and controls on syn‐rift sedimentation
Authors: Gawthorpe Rob L. , Fabregas Natacha , Pechlivanidou Sofia , Ford Mary , Collier Richard E. Ll. , Carter Gareth D. O. , McNeill Lisa C. , Shillington Donna J. 
Published: April 2022

AbstractSyn‐rift deep‐water muds and mudstones preserve a relatively complete stratigraphic record of tectonic and climatic events. This paper investigates mud‐dominated deposits and stratigraphy using core from International Ocean Discovery Program (IODP) Expedition 381 sites M0078 and M0079 in the Gulf of Corinth, Greece. Millimetre‐scale logging defined several bed types: homogeneous and laminated mud beds, bioturbated beds, a variety of graded beds, and rare matrix‐supported conglomerates and slumps. Homogeneous muds and light grey to black laminated muds record deposition from distal, waning low density turbidity currents and terminal mud‐rich quasi‐laminar or laminar plug flows. Graded beds, interpreted as turbidites, range from beds several millimetre to a few centimetres of mud with silt to fine sand bases, to metre‐scale mud beds with coarser sand and pebble bases. Conglomerate and slumped beds record cohesive debris flows, transitional flows and slope failure. Three stratal package types are distinguished: bioturbated, bedded and laminated, recording distinct hydrological conditions. Bioturbated packages record interglacial marine conditions with well oxygenated waters. Bedded packages record hemipelagic processes and low energy density underflows in a mainly dysoxic, stratified, lacustrine setting (glacial phases). In laminated packages, white mm‐scale laminae of calcite or aragonite from varved, hemipelagic sediments demonstrating seasonal variability in a dysoxic non‐marine or transitional setting. Rift stratigraphy is linked to eustatically controlled connections to the global ocean across rift segment boundaries. The ca. 780 to 330 ka succession is dominated by laminated packages with thin bioturbated packages and distinct conglomerates and slumps, suggesting high sills, making ocean connections brief and transitional to lacustrine conditions prolonged. The ca. 330 ka to present succession shows well developed bioturbated and bedded packages, separated by thin laminated packages, suggesting brief transitions and well‐developed marine conditions due to lower sills. Results indicate that structurally controlled rift segment boundaries exert a first‐order control on syn‐rift stratigraphic evolution, with fault segment growth and linkage driving intra‐rift facies and sequence variability.
Tectono‐stratigraphic evolution of the rift and post‐rift systems in the Northern Campos Basin, offshore Brazil
Authors: Strugale Michael , Cartwright Joe 
Published: April 2022

AbstractThe Campos and Santos Basins have been a focus of subsurface studies since the discovery in 2006 of large accumulations of hydrocarbons in the Early Cretaceous rift and post‐rift strata below Aptian evaporites. In this study, regional 2D seismic lines, a 3D seismic survey and well data were interpreted to reconstruct the tectono‐stratigraphic evolution of the rift and post‐rift stages in the northern sector of the Campos Basin. Detailed 3D seismic interpretation and geological modelling were used to subdivide the pre‐salt sedimentary record. This revealed a diachronous strain distribution along the Guriri Fault System (GFS), a roughly NE‐SW striking fault‐bounded horst that was a focus of rift‐related deformation. The syn‐rift succession is interpreted to be the product of two episodes of rifting (RP1 and RP2) with contrasting fault activity patterns and lithostratigraphy. Volcaniclastics and coarse siliciclastics of RP1 were deposited under WNW‐ESE transtension that formed discontinuous half‐grabens followed by extensive erosion and tectonic inversion. Structurally controlled bioclastic rudstones and hybrid deposits characterize RP2 and were deposited in elongated half‐grabens that delimit the GFS horst, which developed under an NW‐SE extension. Deposition under increasingly less tectonically active transitional and post‐rift stages dominated by thermal subsidence gradually led to the healing of the rift‐related structural relief. Selective reactivation of rift faults testifies active tectonic inversion through compression from immediate post‐rift throughout evaporite deposition. These interpretations are put into the context of recent geochronological data of onshore dyke emplacement and the new age constraints for the end of deposition of the pre‐salt sequence. Therefore, we propose an earlier onset on rifting in the Campos Basin, at the Berriasian.
Radiotherapy plus androgen deprivation therapy for prostate‐specific antigen persistence in lymph node–positive prostate cancer
Authors: Shiota Masaki , Takamatsu Dai , Kimura Takahiro , Tashiro Kojiro , Matsui Yoshiyuki , Tomida Ryotaro , Saito Ryoichi , Tsutsumi Masakazu , Yokomizo Akira , Yamamoto Yoshiyuki , Edamura Kohei , Miyake Makito , Morizane Shuichi , Yoshino Takayuki , Matsukawa Akihiro , Narita Shintaro , Matsumoto Ryuji , Kasahara Takashi , Hashimoto Kohei , Matsumoto Hiroaki , Kato Masashi , Akamatsu Shusuke , Joraku Akira , Kato Manabu , Yamaguchi Takahiro , Saito Toshihiro , Kaneko Tomoyuki , Takahashi Atsushi , Kato Takuma , Sakamoto Shinichi , Enokida Hideki , Kanno Hidenori , Terada Naoki , Suekane Shigetaka , Nishiyama Naotaka , Eto Masatoshi , Kitamura Hiroshi ,   the Japanese Urological Oncology Group
Published: April 2022

AbstractThe treatment for lymph node involvement (LNI) after radical prostatectomy (RP) has not been established. This study aimed to reveal the outcomes of various management strategies among patients with LNI after RP. Retrospectively, 561 patients with LNI after pelvic lymph node dissection (PLND) with RP treated between 2006 and 2019 at 33 institutions participating in the Japanese Urological Oncology Group were investigated. Metastasis‐free survival (MFS) was the primary outcome. Patients were stratified by prostate‐specific antigen (PSA) persistence after RP. Cox regression models were used to analyze the relationships between clinicopathological characteristics and survival. Survival analyses were conducted using the Kaplan‐Meier method and log‐rank test with or without propensity score matching. Prognoses, including MFS and overall survival, were prominently inferior among patients with persistent PSA compared with those without persistent PSA. In multivariate analysis, androgen deprivation therapy (ADT) plus radiotherapy (RT) was associated with better MFS than ADT alone among patients with persistent PSA (hazard ratio = 0.37; 95% confidence interval = 0.15‐0.93; p = 0.034). Similarly, MFS and overall survival were significantly better for ADT plus RT than for ADT alone among patients with persistent PSA after propensity score matching. This study indicated that PSA persistence in LNI prostate cancer increased the risk of poor prognoses, and intensive treatment featuring the addition of RT to ADT might improve survival.
Keratosis follicularis spinulosa decalvans-like cicatricial alopecia in a patient with cardiofaciocutaneous syndrome
Authors: Murad Aizuri , Bergfeld Wilma 
Published: April 2022

Abstract
We describe a patient with the keratosis pilaris atrophicans variant of cicatricial alopecia in conjunction with cardiofaciocutaneous syndrome.
'It's the way they look at you': Why discrimination towards young parents is a policy and practice issue
Authors: Owens Rachael 
Published: April 2022

AbstractQualitative research has long critiqued a simplistic association between youth parenting and poor outcomes. Despite this, the UK youth parenting policy continues to view young parents through a narrow deficit lens, focused on assumed risk rather than structural inequalities. The paper brings together the direct accounts of young parents' experiences, with ethnographic observation of practice, to argue that discrimination is the critical issue associated with being a young parent. This is then set within a wider critique of the policy framework which, it is argued, perpetuates and normalises negative ideas about young parents prevalent in political, societal and cultural processes. An integrative theoretical approach is used to highlight how a deficit lens at a policy level upholds, rather than undermines, young parents' intersectional experiences of discrimination and has ethical implications for practitioners working with them. The paper calls for a reorientation of policy which addresses and disrupts discrimination.