bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of the position of confining transverse links on lap strength
Authors: Metelli Giovanni , Marchina Egidio , Plizzari Giovanni A. 
Published: February 2022

AbstractThe article presents the results of an experimental campaign to investigate the effect of the position of transverse links on the strength of lap splices in tension. Lap splices with transverse links either adjacent to the lapped bars or at a distance of 4.5 times the bar diameter from the lap were tested. The stirrups index of confinement was similar in all the specimens. The results show a reduction of the lap strength up to 15% when the transverse links are not close to the lapped bars because of the splitting crack propagation which is not adequately counteracted by the confining action of the links. The test results show that the provisions of MC2010 for lap splices, with links relatively far, may be unconservative. Furthermore, an experimental database on the strength of lap splices with different distances of transverse links to the lapped bars is gathered from studies published in literature. This database enables to assess the accuracy of the efficiency factor km of confining reinforcement in the fib MC2010 formulation. Based on the statistical analysis of the test results concerning the confining reinforcement, a reduction is proposed for the effectiveness factor (km), to be applied whenever the distance of laps to the transverse links exceeds four times the bar diameter.
Portraying secondary science teacher retention with the person‐position framework: An analysis of a state cohort of first‐year science teachers
Authors: Larkin Douglas B. , Patzelt Suzanne Poole , Ahmed Khadija M. , Carletta Liz , Gaynor Catherine R. 
Published: February 2022

AbstractThis study uses state‐level staffing data to analyze the five‐year career trajectories of all 231 first‐year secondary science teachers in New Jersey who began teaching during the 2010‐2011 school year. The person‐position framework for studying teacher retention is introduced in this analysis, and the authors present a case for the importance of specifying both location and duration in empirical reporting on teacher retention, as well as distinguishing between the employers’ and individual teachers’ perspectives on retention. In the cohort studied here, the 5‐year retention‐by‐employer rate was 38%, but the retention‐in‐profession rate for those actively teaching was 65%. An additional 24% of science teachers changed districts during or immediately after their first year, and were retained in their second districts for four or more years. 16% of the science teachers in the cohort identified as non‐White or Hispanic and these teachers were retained at similar rates to their White/non‐Hispanic counterparts. Alternate route preparation programs attracted many more secondary science teachers who identified as non‐White or Hispanic, but teachers from these programs had a far lower 5‐year retained‐in‐profession rate (45%) than non‐White or Hispanic traditional route teachers (75%). It was more common for science teachers in higher SES districts to transfer to lower SES districts than the reverse. The position turnover rate for science teachers was slightly lower in higher SES districts. As a category, charter schools had the lowest 5‐year science teacher retention rate (13%). There was no identifiable relationship between the age, sex, subject area certification, or starting salary of science teachers and the measures of retention used in this study. The authors discuss the characterization of retention itself in research, including the use of descriptors related to retention. Implications relating to science teacher education policy are discussed, as is the future use of state‐level data systems in retention research.
Prevalence of Eimeria spp. with associated risk factors in dairy calves in Sylhet, Bangladesh
Authors: Chandra Deb Liton , Ahmed Syed Sayeem Uddin , Baidhya Chandan Chandra , Deb Nath Nirmalendu , Ghosh Sumon , Paul Suman 
Published: February 2022

AbstractBackgroundBovine eimeriosis is thought to be very important for the productivity and health of cattle all over the world. Despite the importance of cattle farming in Sylhet, little is known about the prevalence of bovine Eimeria spp. and the risk factors connected with it.ObjectivesWe conducted a study to evaluate the prevalence, species diversity and associated risk factors of Eimeria spp. in a population of 50 cattle farms from 12 upazilas (sub‐district) in Sylhet district.MethodsFaecal samples were collected randomly from a total of 554 calves ranging in age from 1 month to 2 years old during a period of 7 months. We used Flotation and McMaster techniques for parasitological examination. Species identification was done by using their morphological and morphometric characteristics.ResultsOut of 554 calves, 308 were found to be positive for Eimeria species (55.60%). Seven species of Eimeria were identified. Among the identified species, E. bovis (38.98%), E. zuernii (26.17%) and E. alabamensis (22.38%) were found to be the most prevalent species. Mixed and species‐specific Eimeria infection were (24.73%; 95% CI 21.32–28.49) and (30.87%; 95% CI 27.17–34.84), respectively. In addition, the highest prevalence was observed at Zakigonj (68%; 95% CI 58.34–76.33) and the lowest at Companygonj (40%; 95% CI 30.94–49.80). Eimeria species intensity ranged between 50 and 76,550 oocyst per gram of faeces. Analysis of associated risk factors by using multivariate logistic regression analysis revealed that age, gender and body condition were significantly (p < 0.05) associated with Eimeria infection.ConclusionsBased on these present findings, it can be assumed that ‘coccidia belong to the most prevalent pathogens in the population of calves in the study area’. Thus, the findings of this study could be used as tools for adoptive surveillance and effective control and prevention of the disease in cattle populations in this region.
Effect of different processing techniques and presence of antioxidant on the chitosan film performance
Authors: Infurna Giulia , Cavallaro Giuseppe , Lazzara Giuseppe , Milioto Stefana , Dintcheva Nadka Tz. 
Published: February 2022

AbstractIn the last two decades, the naturally occurring polysaccharides have gained great attention because of their potential applications in different sectors, for example, from food to biomedical sectors. Chitosan is a cationic polysaccharide with good transparency, and currently, it has been considered also as suitable material for the formulation film and coating in cultural heritage protection. In this work, the chitosan films (Ch), with and without natural antioxidant such as citric acid (CA), are formulated considering two different processing techniques: (i) conventional solvent casting and (ii) compression molding, that is an unconventional method for this polysaccharide, giving the possibility to formulate films with extended surface and constant thickness. The effects of processing conditions and antioxidant presence on the properties and performance are evaluated by thermo‐gravimetric analysis, FTIR and UV–visible spectroscopy, water contact angle measurements and tensile test. Besides, the durability of all investigated Ch and Ch/CA has been evaluated subjecting thin film to UVB exposure and monitoring their structural changes by FTIR analysis in time. All obtained results suggest that the chitosan films can be processed successfully by both solvent casting and compression molding techniques. Further, the CA presence in Ch films has a beneficial effect on the thermal resistance and durability and no negative effect on the transparency and optical properties.
Papillary meningioma with multifocal leptomeningeal spread in a dog
Authors: Santifort Koen , Van Soens Iris , Beukers Martijn , Grinwis Guy , van der Lugt Jaco , Mandigers Paul 
Published: February 2022

AbstractAn 11‐year‐old, English cocker spaniel was presented with subacute progressive signs of vestibular ataxia, tetraparesis, left‐sided proprioceptive deficits, positional ventrolateral strabismus of the right eye and a right‐sided menace deficit. Magnetic resonance imaging of the cranium and cranial cervical spinal cord revealed multifocal T2 hyper‐/T1‐hypointense intradural lesions with dural tail signs and intra‐axial and intramedullary extension. Medical treatment resulted in initial improvement before deterioration was noticed. Cytological examination results of computed tomography‐guided fine‐needle aspiration biopsy of the C1–C2 lesion were consistent with mesenchymal neoplasia. Three days later, after progressive clinical deterioration, euthanasia was performed. Postmortem examination and subsequent histological examination of the brainstem and spinal cord revealed multifocal, strongly infiltrative growth of neoplastic cells with areas of pseudo‐rosette formation by cylindrical neoplastic cells with moderately large, oval nuclei in addition to areas of spindle‐shaped neoplastic cells with meningothelial whorls. The final diagnosis was a papillary (grade III) meningioma with multifocal leptomeningeal spread.
Die Hand positionieren, um zu agieren – Validierung des 8-Punkte-Greifraum-Tests
Authors: Krupp Sonja , Petersen Theresa , Balck Friedrich , Kasten Meike , Willkomm Martin , Kasper Jennifer 
Published: February 2022

Zusammenfassung
Hintergrund
Das standardisierte geriatrische Assessment der oberen Extremitäten beschränkt sich häufig auf die Messung der Handkraft. Als einziges weiteres Instrument nennt die S1-Leitlinie zum geriatrischen Assessment der Stufe 2 den 20-Cents-Test (20-C-T). Neben Kraft und Feinmotorik ist jedoch das erfolgreiche Platzieren der Hand eine Voraussetzung für die Selbstversorgung.

Ziel der Arbeit
Zur standardisierten seitengetrennten Überprüfung des alltagsrelevanten Positionierens der Hand im Sitzen wurde der 8‑Punkte-Greifraum-Test (8P-GRT) entwickelt. Die Studie diente der Ermittlung von Gütekriterien des 8P-GRT bei geriatrischen Krankenhauspatienten.

Material und Methoden
Zwischen dem 31.07.2019 und dem 23.09.2019 wurden im Krankenhaus Rotes Kreuz Lübeck – Geriatriezentrum 82 stationäre Patienten mithilfe des 8P-GRT, des Shoulder Pain and Disability Index (SPADI), einem zu den Handpositionen des 8P-GRT korrespondierenden Fragebogen zu Aktivitäten der Selbstversorgung, der Handkraftmessung und dem 20-C‑T untersucht.

Ergebnisse
Die Interrater-Reliabilität betrug 0,99, die Retest-Reliabilität 0,95 für die rechte und 0,90 für die linke Seite. Auf die Person bezogen, trat ein Deckeneffekt (beidseits Score 8) bei 4,1 % (n = 3) auf; kein Bodeneffekt wurde beobachtet. Die interne Konsistenz (Cronbachs α) des gemäß Faktorenanalyse zweifaktoriellen Tests betrug 0,78 (rechts) bzw. 0,76 (links). Jeder der anderen Tests korrelierte enger mit dem 8P-GRT auf der rechten Seite, wobei die Korrelation mit dem oben genannten Fragebogen am höchsten war (−0,72), gefolgt vom SPADI (−0,60).

Diskussion
Eine standardisierte Erhebung der Handkraft, Feinmotorik und aktiven Positionierung der Hand (z. B. 8P-GRT) fügt die Hauptaspekte der Funktionsfähigkeit der oberen Extremitäten zu einem Gesamtbild zusammen.
Creatinine-based GFR-estimating equations in children with overweight and obesity
Authors: van Dam Mark J. C. M. , Pottel Hans , Vreugdenhil Anita C. E. 
Published: February 2022

Abstract
Background
With the increasing prevalence of childhood obesity and related development of chronic kidney disease (CKD), there is a critical need to understand how best to assess kidney function in children with obesity. Since serum creatinine (SCr) is recommended as marker of first choice for GFR estimation, we evaluated and compared creatinine-based GFR equations in children with overweight and obesity.

Methods
Six hundred children with overweight and obesity (53.5% female; mean age 12.20 ± 3.28 years; mean BMI z-score 3.31 ± 0.75) were included from the Centre for Overweight Adolescent and Children’s Healthcare (COACH).

Results
Serum creatinine (SCr), normalized using Q-age polynomials obtained from reference values, results in median and mean SCr/Q value close to “1” for all age groups, and 96.5% of the children have a SCr/Q within the reference band [0.67–1.33], corresponding to the 2.5th and 97.5th percentile. eGFR CKiD (bedside Schwartz equation) and Schwartz-Lyon decreased with age, whereas eGFR EKFC and modified CKD-EPI40 showed no age-dependency, but the distribution of eGFR values was not symmetrical. eGFR CKiD under 25 (CKiDU25) demonstrated no age-dependency but major sex differences were observed. eGFR FAS age, FAS height, and adjusted-creatinine revised Lund-Malmö (LMR18) showed a relatively symmetrical distribution and no age-dependency.

Conclusions
Serum creatinine (SCr) values of children with overweight and obesity are mostly within the reference range for children. Normalization of SCr using reference Q-age polynomials works very well in this cohort. After evaluation of the different equations, we suggest that FAS age, FAS height, and LMR18 are the preferred creatinine-based GFR-estimating equations in children with overweight and obesity.
Clinical trial registration.
ClinicalTrial.gov; Registration Number: NCT02091544.

Graphical abstract
A higher resolution version of the Graphical abstract is available as Supplementary information
Sustainability assessment of short food supply chains (SFSC): developing and testing a rapid assessment tool in one African and three European city regions
Authors: Doernberg Alexandra , Piorr Annette , Zasada Ingo , Wascher Dirk , Schmutz Ulrich 
Published: February 2022

AbstractRecent literature demonstrates the contribution of short food supply chains (SFSC) to regional economies and sustainable food systems, and acknowledges their role as drivers for sustainable development. Moreover, different types of SFSC have been supported by urban food policies (UFP) over the few last years and actors from the food chain became part of new institutional settings for urban food policies. However, evidence from the sustainability impact assessment (SIA) of these SFSC in urban contexts is limited. Our paper presents an approach for the development of an SIA framework for different SFSC types. In addition, a practical application of the tool in four metropolitan regions (Berlin, London, Ljubljana and Nairobi) is tested. The conceptual development of the SIA framework is based on an in-depth analysis of existing SIA frameworks and methods for assessing the sustainability of agriculture, food chains and food systems and adapted to the specific needs of analysing SFSC in metropolitan regions. The operational value and utility of the framework and the tool were tested with social and natural scientists and local stakeholders. The assessment results demonstrate that SFSC seems to be more sustainable than the baseline (long global food chains) in the social dimension, but also feature specific strengths and weaknesses concerning their economic and environmental sustainability. This might give an indication for regional adjusted strategies and food chain innovations that improve the sustainability performance may be required. We found the tool useful for framing the dialogue between food chain actors, consumers and policy, because it makes benefits and trade-offs of the chain types operating in an urban–rural context more visible and communicable.
The therapeutic potential of RNA Polymerase I transcription inhibitor, CX-5461, in uterine leiomyosarcoma
Authors: Kang Chang-Won , Hannan Katherine M. , Blackburn Anneke C. , Loh Amos H. P. , Hong Kuick Chik , Yuan Goh Jian , Hein Nadine , Drygin Denis , Hannan Ross D. , Coupland Lucy A. 
Published: February 2022

Summary
Background. Uterine leiomyosarcoma is a rare aggressive smooth muscle cancer with poor survival rates. RNA Polymerase I (Pol I) activity is elevated in many cancers supporting tumour growth and prior studies in uterine leiomyosarcoma revealed enlarged nucleoli and upregulated Pol I activity-related genes. This study aimed to investigate the anti-tumour potential of CX-5461, a Pol I transcription inhibitor currently being evaluated in clinical trials for several cancers, against the human uterine leiomyosarcoma cell line, SK-UT-1. Methods. SK-UT-1 was characterised using genome profiling and western blotting. The anti-tumour effects of CX-5461 were investigated using cell proliferation assays, expression analysis using qRT-PCR, and BrdU/PI based cell cycle analysis. Results. Genetic analysis of SK-UT-1 revealed mutations in TP53, RB1, PTEN, APC and TSC1 & 2, all potentially associated with increased Pol I activity. Protein expression analysis showed dysregulated p53, RB1 and c-Myc. CX-5461 treatment resulted in an anti-proliferation response, G2 phase cell-cycle arrest and on-target activity demonstrated by reduced ribosomal DNA transcription. Conclusions. SK-UT-1 was confirmed as a representative model of uterine leiomyosarcoma and CX-5461 has significant potential as a novel adjuvant for this rare cancer.
Size variation, allometry and mating success in Aotearoa|New Zealand kelp flies (Coelopidae)
Authors: LeGrice Rebecca J. , Holwell Gregory I. 
Published: February 2022

AbstractThe need to respond quickly to the presence of an ephemeral resource required for breeding is often a feature of scramble competition mating systems. Scramble competition mating systems can feature extreme levels of sexual conflict and coercive mating by males. As a result, sexual selection can act on various traits used by males to overcome female resistance behaviours. Selection on these traits may result in significant intra and intersexual size variation and sexual dimorphism. Additionally, traits that influence mating success in males often show positive static allometry. Kelp flies (Coelopidae) are a small family of Diptera which specialise on wrack (beach cast marine macroalgae), a highly ephemeral resource. The mating system of these flies involves high levels of sexual conflict, with females rejecting all male mating attempts. In this study we describe intra and intersexual size variation and static allometry of traits in two of Aotearoa|New Zealand’s species, Coelopella curvipes and Chaetocoelopa littoralis. In addition, we investigate the mating behaviour of C. littoralis under ecologically relevant mating conditions. We found high levels of variation in both species with significant evidence of sexual dimorphism across all traits measured in C. littoralis, and in mid tibia length in C. curvipes. Furthermore, mid tibia length in both species exhibits positive static allometry and is disproportionally larger in larger males, suggesting that this trait in particular may be under strong sexual selection. We found that larger male C. littoralis which attempt to mate are significantly more likely to mate successfully demonstrating a large-size advantage in this species similar to findings across the Coelopidae. However, we only found a non-significant trend towards a mating advantage for males with longer mid-tibiae. We discuss these findings with reference to the population dynamics and ecology of these species.
Multinational ownership patterns and anti-tax avoidance legislation
Authors: Prettl Axel , von Hagen Dominik 
Published: February 2022

AbstractWe investigate whether controlled foreign corporation (CFC) rules influence cross-border merger and acquisition (M&A) activity on a global scale. CFC rules are one main anti-tax avoidance measure and potentially lead to immediate taxation of foreign subsidiaries’ income at parent level. Analyzing a large M&A data set and detailed self-compiled CFC rule data from 27 countries using two different econometric perspectives, we show if and how CFC rules distort firm behavior and ownership patterns. First, we find that the probability of being the acquirer of a low-tax target decreases if CFC rules may be applicable to this target’s income. Second, we show that CFC rules alter an acquirer’s choice of targets’ location. Altogether, our study shows that for affected acquirer countries, CFC rules lead to less M&A activity in low-tax countries due to potentially reduced incentives to shift income. However, these effects appear to be rather small in size and decrease over time. Thus, our study suggests that CFC rules do not substantially bias the market for corporate control as lobby groups partially claim and policy makers can be confident in reaching their goals of diminishing profit shifting with this increasingly important anti-tax avoidance rule.
Efficient and Robust Background Modeling with Dynamic Mode Decomposition
Authors: Krake Tim , Bruhn Andrés , Eberhardt Bernhard , Weiskopf Daniel 
Published: February 2022

AbstractA large number of modern video background modeling algorithms deal with computational costly minimization problems that often need parameter adjustments. While in most cases spatial and temporal constraints are added artificially to the minimization process, our approach is to exploit Dynamic Mode Decomposition (DMD), a spectral decomposition technique that naturally extracts spatio-temporal patterns from data. Applied to video data, DMD can compute background models. However, the original DMD algorithm for background modeling is neither efficient nor robust. In this paper, we present an equivalent reformulation with constraints leading to a more suitable decomposition into fore- and background. Due to the reformulation, which uses sparse and low-dimensional structures, an efficient and robust algorithm is derived that computes accurate background models. Moreover, we show how our approach can be extended to RGB data, data with periodic parts, and streaming data enabling a versatile use.
Effect of intraoperative personalized goal-directed hemodynamic management on acute myocardial injury in high-risk patients having major abdominal surgery: a post-hoc secondary analysis of a randomized clinical trial
Authors: Kouz Karim , Bergholz Alina , Diener Oliver , Leistenschneider Maximilian , Thompson Christina , Pichotka Friederike , Trepte Constantin , Schwedhelm Edzard , Renné Thomas , Krause Linda , Nicklas Julia Y. , Saugel Bernd 
Published: February 2022

AbstractAcute myocardial injury is common after noncardiac surgery and associated with mortality. Impaired intraoperative cardiovascular dynamics are a risk factor for acute myocardial injury. Optimizing intraoperative cardiovascular dynamics may thus reduce acute myocardial injury. We aimed to investigate the effect of intraoperative personalized goal-directed hemodynamic management on the incidence of acute myocardial injury. We hypothesized that personalized goal-directed hemodynamic management reduces the incidence of acute myocardial injury compared to routine hemodynamic management in high-risk patients having major abdominal surgery. We performed a post-hoc secondary analysis of a randomized clinical trial including 180 high-risk major abdominal surgery patients that were randomized to personalized goal-directed hemodynamic management or routine hemodynamic management. We compared the incidences of acute myocardial injury—defined according to the Fourth Universal Definition of Myocardial Infarction (2018)—between patients randomized to personalized goal-directed hemodynamic management or routine hemodynamic management by calculating the relative and absolute risk reduction together with 95% Wald confidence intervals and P values. Acute myocardial injury occurred in 4 of 90 patients (4%) in the personalized goal-directed hemodynamic management group and in 12 of 90 patients (13%) in the routine hemodynamic management group (relative risk: 0.33, 95% confidence interval: 0.11 to 0.99, P = 0.036; absolute risk reduction: − 9%, 95% confidence interval: − 17% to − 0.68%, P = 0.034). In this post-hoc secondary analysis, intraoperative personalized goal-directed hemodynamic management reduced the incidence of acute myocardial injury compared to routine hemodynamic management in high-risk patients having major abdominal surgery. This needs to be confirmed in larger prospective trials.