bluuebunny/crossref_metadata_2025_split huggingface dataset:
Posterior Reversible Encephalopathy Syndrome with Postoperative Hematoma After C4-C6 Spinal Fusion: A Case Report
Authors: Porter Matt , Schmitz Miguel A. 
Published: June 2022

Case:
A 71-year-old woman with a 2-year history of spondylosis and radiculopathy presented with progressively worsening cervical spine pain and neurological dysfunction for 2 years. The patient developed posterior reversible encephalopathy syndrome (PRES) after postoperative hematoma in the retroesophageal and retropharyngeal areas. This occurred status post anterior cervical diskectomy and fusion (ACDF) of C4-C6. One year postoperatively, the patient recovered with full ambulation, neurological improvement, and resolution of all PRES signs and symptoms.

Conclusion:
We present a case of a previously undescribed outcome of PRES as a complication of ACDF likely related to postoperative hypertension and fragile blood vessels.
Pre-processing of handwritten signature images for following recognition
Authors: Akhundjanov U. Yu. , Starovoitov V. V. 
Published: June 2022

In the process of handwritten signature recognition, preprocessing is an important step before calculation its informative features. Signatures of any person always have some differences, in addition, they can be of different colors, sizes and orientations. After signature digitization, their images may contain some noise. The purpose of signature image preprocessing is to obtain the most invariant representation of the digital image of a person's signature, which will allow us to identify him or define that the signature is forged.This paper describes a sequence of transformations necessary to perform preprocessing of the signature image and form its representation of a single orientation and size. It is assumed that there are no graphic elements in the image that are not related to the signature and the background is relatively uniform. The transformations under consideration sequentially perform binarization of the signature image, its filtering, rotation, cropping of the circumscribed rectangle and scaling to a fixed size.The described preprocessing procedures were applied to a number of available digital signature image databases, such as CEDAR, BHSig260-Bengali, BHSig260-Hindi. Experiments on signature recognition confirm that the presented approach to the signature image preprocessing leads to increasing of the recognition accuracy.
Seaweed (Gracilariopsis funicularis) biochar incorporation into a goat manure-food waste vermicompost for optimized vermi-degradation and nutrient release
Authors: Katakula Asteria , Gawanab Werner , Handura Berthold , Itanna Fisseha , Mupambwa Hupenyu Allan 
Published: June 2022

Abstract
Vermicomposts are organic fertilizer sources that are being promoted, however their concentration of macro nutrients such as (NPK) are very low. This study therefore evaluated the biochar from seaweed ( Gracilariopsis funicularis ) incorporated into a goat manure-food waste mixture at 0% (control); 2%; 4%; 6% and 8% on compost degradation and macro-nutrient release. After 10 weeks of vermicomposting the highest pH of 9.06 was observed within the control whilst the lowest was 8.7 in the 8% treatment. The electrical conductivity showed a positive relationship with the level of biochar incorporation with the highest of 16.5 mS/cm from the 8% treatment whilst the lowest was within the control with 6 mS/cm. There were no significant differences between treatments on humification parameters, however there were significant differences on the changes of C/N ratio with the final C/N ratio of 14.4; 14.9; 16.7; 15.1 and 14.4 for the control; 2%; 4%; 6%; and 8% treatments respectively. Higher incorporation rate resulted in the higher concentration of potassium with a value of 32.3 g/kg at week 8. The final percentage change in Olsen P was 19%: 14.2%; 7.3%; 4.1% and 3.0% for the 8%; 6%; control; 4%; and 2% treatments, respectively. An optimized level of 6 to 8 % biochar incorporation ratio can be recommended. However, incorporation of G. funicularis biochar does not seem to influence changes in the vermi degradation efficiency, though it can significantly improve the macro nutrients like P, K and Mg concentrations as well as the macro element concentrations.
Annular structures in perturbed low mass disc-shaped gaseous nebulae II: general and polytropic models
Authors: PLETSER Vladimir 
Published: June 2022

Abstract
This is the second of two papers where we study additional analytical solutions of a bidimensional low mass gaseous disc rotating around a central mass and submitted to small radial perturbations. In a first Paper, hydrodynamics equations were solved for the equilibrium and perturbed configurations and a wave-like equation for the gas perturbed specific mass was deduced and solved analytically for several cases of exponents of the power law distributions of the unperturbed specific mass and sound speed. In this paper, two other general cases of exponents, including a polytropic case, are solved analytically for small frequencies of the perturbations. Similar conclusions to the ones of Paper I are found, namely that the maxima of the gas perturbed specific mass are exponentially spaced and that their distance ratio is a constant, function of disc characteristics and of the perturbations frequency. Gaseous annular structures would eventually be formed in the disc by inward and outward gas ows from zones of minima toward zones of maxima of perturbed specific mass.
CD44+/CD24-Flow Cytometry and Immunohistochemistry on Therapy Response to the Administration of Chemotherapy in Ovarian Cancer
Authors: Sihombing Unedo Hence Markus , Andrijono Andrijono , Purwoto Gatot , Gandamihardja Supriadi , Harahap Alida R. , Rustamadji Primariadewi , Kekalih Aria , Widyawati Retno , Fuady Dzicky Rifqi 
Published: June 2022

Abstract
Ovarian cancer is one of the deadliest women’s cancers. There is much chemoresistance to ovarian cancer standard therapy. CD44+/CD24- have an essential role in developing chemoresistance and poor prognosis for the patients. We aimed to study CD44+/CD24- relationship with ovarian cancer chemoresistance and its ability to predict chemoresistance. This study is an ambispective cohort study of 32 people in each group at the Obstetrics-gynecology and pathology Department of Cipto Mangunkusumo, Tarakan, Dharmais, and Fatmawati Hospital
Study of the Accuracy of a Radial Arterial Pressure Waveform Cardiac Output Measurement Device After Cardiac Surgery
Authors: Ordoñez-Rufat Pilar , Mancho-Fora Núria , Tebé-Cordomí Cristian , Polit-Martínez Victoria , Abellán-Lencina Ricardo , Fernandez-Álvarez Joaquin , Lopez-Delgado Juan Carlos 
Published: June 2022

Abstract
Background: Less invasive monitoring, such as radial arterial pulse contour analysis (ProAQT® sensor), represents an alternative when hemodynamic monitoring is necessary to guide postoperative resuscitation and invasive monitoring is not technically feasible. The aim of the study is to evaluate the accuracy of the ProAQT® sensor measurements in comparison with Pulmonary Artery Catheter (PAC) during the postoperative course of patients who underwent cardiac surgery with cardiopulmonary bypass.Case presentation: Prospective observational study in a Surgical Intensive Care Unit of a tertiary university hospital. Ten patients with a mean age of 73.5 years were included. The main comorbidities were hypertension, diabetes, dyslipidemia and the preoperative left ejection fraction was 43.8±14.5%. Regarding the type of surgery, six patients underwent valve surgery, two underwent coronary artery bypass grafting and two underwent aortic surgery. The cardiac index measured simultaneously by the ProAQT® sensor was compared with the PAC. The parameters were evaluated at predefined time points during the early postoperative courses (6h, 12h, 24h, 48h and 72h). The degree of agreement with the cardiac index between the PAC and the ProAQT® sensor along the time points was measured using the concordance correlation coefficient, Bland-Altman analysis and four-quadrant plot.Sixty-three pairs of measurements were analyzed. We showed that measurements of cardiac index were slightly higher with PAC (β ̂=-0.146, p-value=0.094). The concordance correlation coefficient for the additive model of cardiac index was 0.64 (95% Confidence Interval: 0.36, 0.82), indicating a high concordance between both sensors. Bland-Altmann analysis showed a mean bias of 0.45 L·min-1·m-2, limits of agreement from -1.65 to 2.3 L·min-1·m-2, and percentage of error was 82.5%. Four-quadrant plot of changes in cardiac index showed a good concordance rate (75%), which increases after applying the exclusion zone (87%).Conclusion: In patients undergoing cardiac surgery, the ProAQT® sensor may be useful to monitor cardiac index during the postoperative period, especially when more invasive monitoring is not possible.
Functional improvement and satisfaction with a wearable hip exoskeleton in community- living adults
Authors: Kim Jihye , Chun Hyelim , Lee Su-Hyun , Lee Hwang-Jae , Kim Yun-Hee 
Published: June 2022

Abstract
Background
Demand for wearable devices and supportive technology is growing as these devices have the potential to enhance physical function and quality of life in users. The purpose of this study was to investigate usability and satisfaction after performing functional and gait exercise with a wearable hip exoskeleton in community-living adults.
Methods
Two-hundred and twenty-five adults (mean age 67.52 ± 10.99) residing in the local community participated in this study. All participants (middle-aged group, n = 75; old-aged group, n = 150) performed 40-minutes of exercise once with a wearable hip exoskeleton in various environments. The EX1 (Samsung Electronics Co., Ltd., Suwon, Republic of Korea), which functions as a wearable hip exoskeleton, was used. Physical function was assessed before and after exercise with the EX1 using the 10-meter walking test (10MWT), four square step test (FSST), timed up and go test (TUG), 6-minute walking test (6MWT), and short physical performance battery (SPPB). In addition, after completing exercise with the EX1, the usability and satisfaction questionnaires were evaluated.
Results
Gait speed, TUG, and FSST showed statistically significant improvements after exercise with the EX1 in both groups (p < 0.05). In 6MWT, a significant increase was observed in the middle-aged group (p < 0.05) but not in the old-aged group. In SPPB, there was a significant improvement in the old-aged group (p < 0.05) but not in the middle-aged group. On the other hand, positive results in usability and satisfaction were noticed in both groups. In preference between resistance and assist mode of the EX1, the old-aged group preferred the assist mode and the middle-aged group preferred the resistance mode.
Conclusion
These results demonstrate that a single session of exercise with the EX1 was effective in improving physical performance of both middle- and old-aged adults, with positive feedback from most of the participants.
Trial registration:
Clinical trials registration information: ClinicalTrials.gov Identifier: NCT05106881 (04/11/2021).
How I treat recurrent paediatric high-grade glioma (pHGG): A Europe-wide survey study
Authors: Perwein Thomas , Giese Barbara , Nussbaumer Gunther , Bueren André O. , Buiren Miriam , Benesch Martin , Kramm Christof Maria 
Published: June 2022

Abstract
BACKGROUND: As there is no standard of care treatment for recurrent/progressing paediatric high-grade gliomas (pHGG), we aimed to gain an overview of different treatment strategies. METHODS: In a web-based questionnaire, members of the SIOPE-BTG and the GPOH were surveyed on therapeutic options in four case scenarios (children/adolescents with recurrent/progressing HGG).RESULTS: Most respondents (139 clinicians from 22 European countries) preferred further oncological treatment in three out of four cases and chose palliative care in one case with marked symptoms. Depending on the case, 8-92% would initiate a re-resection (preferably hemispheric pHGG), combined with molecular diagnostics. Throughout all case scenarios, 55-77% recommended (re-)irradiation, preferably local radiotherapy >20 Gy, and most respondents would participate in clinical trials and use targeted therapy (79-99%), depending on molecular genetic findings (BRAF alterations: BRAF/MEK inhibitor, 64-88%; EGFR overexpression: anti-EGFR treatment, 46%; CDKN2A deletion: CDK inhibitor, 18%; SMARCB1 deletion: EZH2 inhibitor, 12%). 31-72% would administer chemotherapy (CCNU, 17%; PCV, 8%; temozolomide, 19%; oral etoposide/trofosfamide, 8%), and 20-69% advocated immunotherapy (checkpoint inhibitors, 30%; tumour vaccines, 16%). Depending on the individual case, respondents would also include bevacizumab (6-18%), HDAC inhibitors (4-15%), tumour-treating fields (1-26%), and intraventricular chemotherapy (4-24%). CONCLUSIONS: In each case, experts would combine conventional multimodal treatment concepts, including reirradiation, with targeted therapy based on molecular genetic findings. International cooperative trials combining a (chemo-)therapy backbone with targeted therapy approaches for defined subgroups may help to gain valid clinical data and improve treatment in paediatric patients with recurrent/progressing HGG.
Coupled plasma filtration adsorption for the treatment of sepsis or septic shock ： a systematic review and meta-analysis
Authors: Li Yuting , Li Hongxiang , Guo Jianxing , Wang Youquan , Zhang Dong 
Published: June 2022

Abstract
Background: The effect of coupled plasma filtration adsorption(CPFA) for the treatment of sepsis or septic shock is controversial. A systematic review and meta-analysis was performed to evaluate the impact of CPFA on all-cause mortality in patients with sepsis or septic shock.Methods: We searched the PubMed, Cochrane, and Embase databases for randomized controlled trials(RCTs) and cohort studies from inception to the 1st of May 2022. We included studies involving patients (˃14 years) with sepsis or septic shock. All authors reported our primary outcome of all-cause mortality(hospital mortality, 28-day mortality or 30-day mortality). Results were expressed as odds ratio (OR) with accompanying 95% confidence interval (CI).Results: Six studies including 537 patients were included. The primary outcome of this meta-analysis showed that the all-cause mortality was about 54.2% (119/243 in the CPFA group and 172/294 in the control group). There was no statistically significant difference in the all-cause mortality between two groups(odds ratio [OR]=0.75;95% CI, 0.53 to 1.06; P=0.11;Chi2=14.04; I2=64%).Conclusions: The treatment of CPFA failed to decrease all-cause mortality of sepsis or septic shock patients. Further large-scale randomized controlled trials (RCTs) evaluating the ability of this therapy to improve clinical outcomes are still required to confirm these results.
Relation between derived cardiovascular indices, body surface area, blood pressure/heart rate recovery among active and inactive Nigerian student
Authors: Ewah Patrick Ayi , Oyeyemi Adetoyeje Y 
Published: June 2022

Abstract
BACKGROUNDThe ease in the computation of derived cardiovascular indices such as mean arterial pressure [MAP], rate pressure product [RPP], and pulse pressure [PP]), make them attractive for use in making clinical decisions for patient management in resource-deprived environments. This study sought to determine the relationship between these indices and heart-rate/blood pressure drops during recovery state among physically active and inactive individuals following submaximal exercise. RESULTSThis quasi-experimental study conveniently sampled 105 apparently healthy male subjects aged 18-35 years of the University of Maiduguri. Inter-group categorization was executed by IPAQ. The derived indices were calculated using heart rate and blood pressure measurement while the body surface area (BSA) was determined using height and weight. The subjects were subjected to a submaximal exercise test using a bicycle ergometer. Data analysis include; descriptive statistic, Pearson correlation, student t-test, analysis of covariance, and multiple linear regression. The data was analyzed using SPSS version 25.0 at a significance of p<0.05. The mean BSA and resting-PP, MAP, and RPP were 1.84±0.16 m2, 41.23±7.57 mmHg, 85.92±9 mmHg, and 8266.45±1404.05 respectively. The resting-RPP of the physically inactive subjects was significantly higher than that of the active (8742.71±1496.31 vs 7790.18±1131.59, p=0.00) however, the active subject had a higher resting MAP than the inactive (87.91±7.98 Vs 83.93±9.59, p=0.03). The relationship between the RPP and the Absolute/percent recovery HR was r=-0.23, p=0.02/r=-0.34, p=0.00. The relationship between the PP and absolute recovery SBP was r=0.22, p= 0.03. The relationship found between the MAP and absolute recovery SBP was (r= 0.33, p= 0.00). The best negative predictor of recovery HR was the RPP while the MAP was the best positive predictor of recovery HR and SBP.CONCLUSIONSOverall, the physically active subjects coped better during the exercise than their inactive counterpart because of lower cardiac work and better blood perfusion to vital body organs. An inverse relationship was found between the RPP and absolute/percent recovery HR at one-minute post-exercise while a positive relationship was found between the PP and absolute drop in SBP/percent drop in DBP one minute post-exercise. The best predictor of recovery in HR and blood pressure was the RPP.
Comparison between direct anterior approach and minimally invasive posterolateral approach for bipolar hemiarthroplasty in elderly patients with femoral neck fracture
Authors: Liu Wei , Lin Wei , Hao Congqiang , Zong Yaqi 
Published: June 2022

Abstract
Background To compare the clinical effect after bipolar hemiarthroplasty（BHA）via the direct anterior approach（DAA）or minimally invasive posterolateral approach（MIPA）following the elderly patients with femoral neck fracture. Methods 196 elderly patients with femoral neck fracture were divided into DAA group (n=98) and MIPA group (n=98) according to the surgical approach. The clinical data，postoperative pain and complications，the time to keep seating for 1 hour and walking independently，postoperative Harris score of functional activity in 6 weeks and 2 years and mortality at 2 years after surgery were compared between the two groups. Results （1）The patients in group DAA had longer operation time, but the patients with pneumonia 72 hours after the operation was less，the VAS score of DAA patients decreased after 24 hours of operation, and the time of keep seating for 1 hour and walking independently was earlier (P< 0.05).（2）6 weeks after the operation, the Harris score of wearing socks and shoelaces , sitting on chairs and climbing stairs in the DAA group was better than that in the MIPA group (P< 0.05). After 2 years, there was no significant difference in Harris scores between the two groups (P> 0.05). Conclusion In the elderly patients with BHA, DAA can be more effective than MIPA to reduce the incidence of complications associated with long-term bed rest, relieve early postoperative pain, and improve the early postoperative hip function.
The Performance Analysis of 802.11p with Cooperative Communication and Dynamic Contention Window
Authors: Septa Neha 
Published: June 2022

Abstract
Road safety applications provided by the Vehicular ad hoc networks demand less delay, high throughput, and reliable communication under highly dense traffic conditions. It becomes very challenging to design a network that suits the high mobility of vehicles and frequently chang ing network topology. To overcome these challenges in the network, we propose a new algorithm to dynamically adapt the contention window size (DYCW) to the vehicle density conditions. Along with that, we have introduced a cooperative relay vehicle for relaying the safety mes sages that failed to reach the destination. We have also carried out analytical study of the proposed model and the simulation results for the our model show that using DYCW enhances the system functioning by leading to higher throughput with stability in the performance and decreases both the delay and the packet drop ratio (PDR) of the system.
Role of Maraviroc and/or Rapamycin in Aging Liver Processes
Authors: Pérez-Martínez Laura , Romero Lourdes , Verdugo-Sivianes Eva M. , Muñoz-Galván Sandra , Rubio-Mediavilla Susana , Amiama Ana , Carnero Amancio , Blanco José Ramón 
Published: June 2022

Abstract
Cellular senescence and low-grade inflammation favor the acceleration of aging. The liver is an essential metabolic organ because changes related to its function are related to age-related diseases. The objective of this study was to evaluate the effects of maraviroc (MVC) and/or rapamycin (RAPA) on liver tissue in an experimental model of aging in mice. Eighty male homozygous IL10KO mice were randomly assigned to one of 4 groups (n = 20): i) IL10KO group; ii) MVC group, iii) RAPA group, and iv) MVC-RAPA group. Liver samples were analyzed. Gene expression quantification, western blotting and histopathological analyses were also performed. The proinflammatory cytokines IL-6 and IL-18 were decreased in MVC and MVC/RAPA groups, and TNF-α was decreased in all therapeutic groups. Galactosidase beta-1, was also significantly reduced in all therapeutic groups, as were NK-kB1 and NF-kB2. In all groups, mTOR and CCL5 were significantly reduced. CCR5 expression was decreased in the MVC and MVC/RAPA groups. MVC and RAPA may protect against some factors involved in liver aging. More studies will be necessary to verify their clinical applications.
The unique nano- and microstructure of twinned foraminiferal shell calcite
Authors: Lastam J. , Griesshaber E. , Yin X. , Rupp U. , Sánchez-Almazo I. , Heß M. , Walter P. , Checa A. , Schmahl Wolfgang W. 
Published: June 2022

Abstract
Diversification of biocrystal arrangement patterns, incorporation of biopolymers at many scale levels and a hierarchical architecture are keys for biomaterial optimization. In contrast to molluscan microstructures that consist of ordered assemblies of regularly shaped biocrystals, shells of modern rotaliid foraminifera comprise variously sized and highly irregularly shaped crystals. Benthic and planktonic foraminiferal shell crystals are mesocrystals. Crystal morphologies range from polyhedral, fibrous, to bladed-platy, with most of them having fractal-dendritic morphologies. In this contribution we investigate the nanometer-scale structure and microstructural arrangement of the fractal-dendritic crystals and demonstrate for planktonic Pulleniatina obliquiloculata, Rotaliida, that these consist of twinned calcite. Each fractal-dendritic crystal-unit comprises twin individuals misoriented to each other by 60°. We report for the twinned crystals a unique microstructure, not yet observed for crystals of other carbonate-shelled organisms. The fractal-dendritic, twinned, crystals consist, at the site of nucleation in a rhizopodial-network, of minute fibrils. With distance away from the nucleation site, fibrils change shape and size and evolve to large, twinned, bladed/platy crystals. Arrays of the latter seam outer shell surfaces. We demonstrate that the twinned, fractal-dendritic, crystals form through growth competition at high supersaturation and pH and discuss the main determinants that lead to P. obliquiloculata calcite formation.