bluuebunny/crossref_metadata_2025_split huggingface dataset:
Longitudinal associations of parental monitoring and delinquent peer affiliation: The potential influence of parental solicitation and monitoring rules
Authors: Vaughan Erin P. , Speck Julianne S. , Frick Paul J. , Robertson Emily L. , Ray James V. , Thornton Laura C. , Wall Myers Tina D. , Steinberg Laurence , Cauffman Elizabeth 
Published: May 2022

AbstractIntroductionPoor parental monitoring has been theorized as a key risk factor for an adolescent's association with deviant peers. However, measurements of parental monitoring often only measure parental knowledge rather than parental monitoring actions, leaving the true longitudinal associations between parental monitoring and peer delinquency unclear.MethodsThe current sample consisted of 1095 male justice‐involved adolescents (13–17 years old at baseline collected between 2011 and 2013) from across the United States who provided survey data every 6 months for 3 years. Longitudinal associations between parental monitoring constructs (i.e., parental solicitation and monitoring rules) and peer delinquency were tested using random intercept cross‐lagged panel models to investigate both between‐individual associations and within‐individual bidirectional effects.ResultsAlthough parental monitoring and peer delinquency were negatively related at a between‐individual level, very few within‐individual directional effects were found. The few within‐individual effects present indicated that parental solicitation predicted greater peer delinquency and peer delinquency predicted fewer parental monitoring rules over time.ConclusionsCurrent findings indicate that, while greater overall parental monitoring is associated with less peer delinquency, there is little evidence that changes in parental monitoring lead to reductions in peer delinquency over time. Results support previous findings suggesting parental monitoring should not be the sole target of intervention for reducing peer delinquency.
Serum transfer RNA‐derived fragment tRF‐31‐79MP9P9NH57SD acts as a novel diagnostic biomarker for non‐small cell lung cancer
Authors: Li Jipeng , Cao Chao , Fang Laifu , Yu Wanjun 
Published: May 2022

AbstractBackgroundtRNA‐derived fragments (tRFs) have been found to have a crucial function in the pathophysiology of cancers. However, the function of tRFs in non‐small cell lung cancer (NSCLC) is yet unknown. The goal of this study was to assess the tRF‐31‐79MP9P9NH57SD serum expression from NSCLC patients and to determine its diagnostic usefulness.MethodsBy using stem‐loop quantitative real‐time PCR, we were able to detect various tRF‐31‐79MP9P9NH57SD expressions in 96 NSCLC serum samples, 96 healthy controls, and 20 pairs of NSCLC serum samples pre‐ and post‐surgery (qRT‐PCR). After that, we analyzed its diagnostic effectiveness using the receiver operating characteristic (ROC) curve.ResultsSerum tRF‐31‐79MP9P9NH57SD expression was higher in NSCLC patients, and levels of tRF‐31‐79MP9P9NH57SD were linked to the clinical stage (p = 0.002) and the malignancy of lymph node (p = 0.012). In addition, after the procedure, the serum tRF‐31‐79MP9P9NH57SD expression in NSCLC patients dropped. With 48.96 percent sensitivity and 90.62 percent specificity, the area under ROC curve (AUC) was 0.733.Conclusionserum tRF‐31‐79MP9P9NH57SD possibly is a new and groundbreaking biomarker for the NSCLC.
Complete wastewater discoloration by a novel peroxidase source with promising bioxidative properties
Authors: Klanovicz Natalia , Stefanski Fábio Spitza , Camargo Aline Frumi , Michelon William , Treichel Helen , Teixeira Antonio Carlos Silva Costa 
Published: May 2022

AbstractBACKGROUNDOur study aimed to characterize and prospect immobilization strategies for a novel fungal peroxidase (POD) and insert it in pollutant remediation context. The enzymatic extract was obtained by submerged fermentation of Trichoderma koningiopsis in an alternative substrate consisting of fresh microalgal biomass. The immobilization efficiency was evaluated by monitoring the residual activity (RA) and the discoloration potential (DP) of a synthetic dye solution. Concomitantly, the POD catalytic properties were explored, and the most promising storage strategy to maintain the enzymatic activity was studied.RESULTSThe novel and non‐purified guaiacol peroxidase from T. koningiopsis expressed a specific activity of up to 7801 U mg−1 in the free form, showing stability when subjected to up to 80 °C in a pH range between 4.0 and 8.0. Furthermore, the bioproduct immobilized on Fe3O4 magnetic nanoparticles, named magnetic nanozymes (MN‐POD), expressed up to 689% RA and 100% removal for the Direct Brown 27 dye. An increase in the enzymatic activity, in both free and immobilized forms, was also observed after storage for up to 8 months. The synthesized magnetic nanozymes showed good reusability, maintaining 13 546 U mg−1 after 10 cycles, and removing 94% of color in a second batch. Toxicological evaluation with Allium cepa indicated that the enzymatic discoloration process with immobilized POD was essential for eliminating genotoxic effects.CONCLUSIONThe T. koningiopsis peroxidase production and immobilization presented in this work are promising for the enzyme market and for wastewater treatment technologies due to their high bioxidative potential. © 2022 Society of Chemical Industry (SCI).
Production of filamentous fungal biomass with increased oil content using olive oil as a carbon source
Authors: Nazir Muhammad Tahir , Soufiani Amir Mahboubi , Ferreira Jorge A , Sar Taner , Taherzadeh Mohammad J 
Published: May 2022

AbstractBACKGROUNDVegetable oil is more difficult for microorganisms to degrade compared with carbohydrates and protein. Oil‐rich waste creates serious environmental and health concerns if it remains untreated. The aim of the work reported here was to evaluate the effects on the nutritional composition of filamentous fungal biomass by growing it in pure olive oil as a carbon source.RESULTSThe growth of different filamentous fungal strains (Aspergillus oryzae,Neurospora intermediaandRhizopus oryzae) was investigated in pure olive oil. A pre‐germination stage of either glucose or yeast extract was necessary for successful fungal growth in olive oil.A. oryzaeshowed superior performance in comparison withN. intermediaandR. oryzaein terms of biomass growth. The obtained biomass fromA. oryzaeandN. intermediawas analyzed for protein, fat, ash and alkali‐insoluble material, where the presence of olive oil had a steering effect on biomass growth (16 g L−1with oilversus4 g L−1without oil). Nutritional composition of the fungal biomass ofA. oryzaecontained 0.33% fat and 48% protein when cultivated in medium without olive oil supplementation, while 31% fat and 14% protein contents were observed in the presence of olive oil‐containing medium. Similar trends for fat and protein contents were observed for the biomass ofN. intermedia. Moreover, microscopy confirmed the presence of oil globules inside the fungal cells.CONCLUSIONSFat composition of fungal biomass can be steered through addition of olive oil, which increases the versatility of the produced biomass for various applications, namely in feed, food and biofuel production. © 2022 The Authors.Journal of Chemical Technology and Biotechnologypublished by John Wiley & Sons Ltd on behalf of Society of Chemical Industry (SCI).
Experience of residents learning about social determinants of health and an assessment tool: Mixed‐methods research
Authors: Mizumoto Junki , Son Daisuke , Izumiya Masashi , Horita Shoko , Eto Masato 
Published: May 2022

AbstractBackgroundEducating healthcare professionals about the social determinants of health is important in improving health outcomes of marginalized patients. Residents' experience of learning about the social determinants of health and a clinical assessment tool remains unclear.MethodsResidents participated in an online session about the social determinants of health and the assessment tool. Using the New World Kirkpatrick Model, we obtained data about participants' experience from various perspectives. The data were analyzed using a concurrent triangulation mixed‐methods design.ResultsThe study included 20 out of 30 residents. Their response was good, and self‐reported learning scores were increased by the session. They learned when to ask about patients' social conditions, what to ask, and how to coordinate medical care appropriately. Participants reported reflecting on their role as medical professionals and implementing new practices based on their learning, as well as concerns about addressing patients' social conditions.ConclusionThrough learning about the social determinants of health, and assessment tools, residents both acquired knowledge and skills, and reflected on their previous practice, accepted patients as they are, understood difficult patients better, and developed interprofessional collaboration. Medical education about the social determinants of health can trigger changes in residents' views.
Patient and medication‐related factors associated with opioid use disorder after inpatient opioid administration
Authors: Swart Elizabeth C.S. , Newman Terri V. , Huang Yan , Howell Robert J. , Han Mei , Good Chester B. , Peasah Samuel K. , Parekh Natasha 
Published: May 2022

AbstractBackgroundExamine baseline factors associated with a new diagnosis of opioid use disorder (OUD) within 12 months postdischarge among opioid‐naïve patients who received an opioid prescription in the inpatient setting.Design/SettingRetrospective cohort (surgery and nonsurgery) study of opioid‐naive patients who had at least one prescription for an opioid during an inpatient hospitalist between 2014 and 2017.ParticipantsTwenty‐three thousand and thirty‐three patients were included.ObjectiveThe primary objective was to determine baseline factors associated with a new OUD diagnosis within 12 months of discharge. Baseline covariates included demographic information, clinical characteristics, medication use, characteristics related to index hospital encounter, and discharge location.Findings2.1% of the sample had a new diagnosis of OUD within a year after receiving an opioid during hospital admission. Patients between ages 25 and 34 had higher odds of a new OUD diagnosis compared to those 65 years of age and older (odds ratio [OR]: 6.98, 95% confidence interval [CI]: 4.02–12.1 [nonsurgery] and 4.69, 95% CI: 2.63–8.37 [surgery]). Patients from a high opioid geo‐rank region had higher odds of OUD diagnosis (OR: 2.08, 95% CI: 1.31–3.31 [nonsurgery] and 1.80, 95% CI: 1.03–3.15 [surgery]). History of nonopioid‐related drug disorder, tobacco use disorder, mental health conditions, and gabapentin use 12 months prior to index date and white race were associated with higher odds of new OUD diagnosis.ConclusionsIt is important to identify and evaluate factors associated with developing a new diagnosis of OUD following hospitalization. This can inform pain management strategies within the hospital and at discharge, and prompt clinicians to screen for risk of OUD.
China's strategy of free trade area and economic regionalism
Authors: Lei Yu , Sui Sophia 
Published: May 2022

AbstractChina's FTA strategy and its efforts in economic regionalism in the Pacific region are providing new impetus to deepening economic interdependence with its partners and domestic reform to sustain the country's economic growth. The FTAs in the Pacific region provide China and its economic partners with convenient access to their mutual markets, investment destinations and resources, expanding their economic cooperation and trade. China is increasingly able to obtain economic benefits from the regional network of FTAs while intensifying its economic and, by extension, political relations with its partners. In the face of the enormous economic benefits, China's partners, particularly those without geopolitical competition and territorial disputes with China, may view China's rise as an “opportunity” for their economic growth and accept its concept of “peaceful rise.” In this sense, China's FTA strategy and the regional network of FTAs may help China reap not only economic but also geopolitical interest, accelerating its rise at the systemic (global) and subsystemic (regional) levels.
Cold sensor, hot topic: TRPM8 plays a role in monocyte function and differentiation
Authors: Trusiano Brie , Tupik Juselyn D , Allen Irving C 
Published: May 2022

AbstractUnderstanding the innate immune system and how aberrant activation or impaired inhibition leads to the development of hyperinflammatory conditions, including inflammatory bowel disease, is crucial for patient management and treatment. An emerging area of interest surrounding dysregulated inflammation focuses on membrane bound transient receptor potential (TRP) ion channels. These channels are permeable to calcium and other cations involved in the balance of leukocyte membrane potential and function, as well as afferent neuron signaling within the myenteric plexus of the GI tract, bladder, and skin. A particular channel, TRPM8, is an important cell surface marker for prostate cancer and participates in the function of cold sensing neurons. Specifically, this ion-gated receptor is shown to be activated by agonists such as menthol and eucalyptus, which aid in the soothing, cooling effects of these agents. Furthermore, the TRPM8 channel is also identified on the surface of resident tissue Mϕs and is also linked to the protective role and release of calcitonin gene-related peptide (CGRP) by sensory neurons.
Internationalization of counseling: Integrating the Western theories and practices into the local ways
Authors: Keklik İbrahim 
Published: May 2022

AbstractThe field of counseling has been expanding over the globe in recent decades. Countries newly establishing the profession seem to adapt Western‐originated theories and practices without sufficient alteration or modification to their local cultures. Turkey with its 70 years of experience with counseling is a significant example. In this paper, the need for integrating foreign theories, concepts, and practices into the local‐host cultures will be discussed from social justice and de‐colonialization point of view.
Tracking and plant growth‐promoting effect of Paraburkholderia tropica MTo‐293 applied to Solanum lycopersicum
Authors: Vio Santiago A. , Bernabeu Pamela R. , García Sabrina S. , Galar María L. , Luna María F. 
Published: May 2022

AbstractParaburkholderia tropica MTo‐293 was applied as an experimental bio‐input to Solanum lycopersicum (tomato) cv. Platense. Different plant growth systems and inoculation strategies were tested to evaluate P. tropica plant colonization at the seedling stage (growth chamber) using culture‐dependent and ‐independent techniques. The effect of P. tropica on plant growth was evaluated in the growth chamber and greenhouse (productive stage) by biomass accumulation and fruit production, respectively. P. tropica was able to colonize the surface and inner root and stem of tomato seedlings regardless of the inoculation strategy—at sowing and/or before transplanting—showing the competitive nature of P. tropica in nonsterile substrate systems. A nested polymerase chain reaction was validated to track P. tropica in tomato plants even in the inner stem with endophytic P. tropica populations of less than 102 CFU g–1 of fresh weight. Efficient colonization of P. tropica correlated with a positive effect on tomato growth when applied at sowing and/or before transplanting: plant growth promotion was observed not only at the seedling stage but also at productive stages improving crop yield in two different seasons. To our knowledge, this report is the first to track and evaluate the plant growth‐promoting effect of P. tropica MTo‐293 in tomato plants grown in nonsterile substrate systems.
Assessing improvement in the fifth‐generation ECMWF atmospheric reanalysis precipitation over East Africa
Authors: Assamnew Abera Debebe , Mengistu Tsidu Gizaw 
Published: May 2022

AbstractThis study aims to assess the performance of European Center for Medium‐Range Weather Forecasting (ECMWF) Reanalysis fifth generation (ERA5) in terms of the progress made over its predecessor, ERA‐Interim, over East Africa (EA) in reproducing observed rainfall. The observed rainfall used as reference rainfall are Global Precipitation Climatology Center (GPCC) and Climate Research Unit Time Series (CRU‐TS). The performance of ERA5 to its predecessor is evaluated using root‐mean‐square error (RMSE), correlation, and bias. The reductions of wet bias from ERA‐Interim to ERA5 are 16.81–6.94% from June to September (JJAS), 31.99–19.33% from September to December (SOND), and 29.24–17.69% from December to February (DJF) over most of EA relative to CRU‐TS. Similar reductions in the wet bias relative to GPCC are also noted. Spatially, notable reductions are observed over western Ethiopia, Sudan Republic, South Sudan, and Uganda. The decreasing trends revealed in the bias of seasonal ERA5 rainfall relative to CRU‐TS and GPCC are attributed to an increase in the number and quality of assimilated observations in ERA5 over its predecessors. RMSE of ERA5 rainfall relative to the two reference rainfall and correlations with the two reference rainfall are consistent with spatial and temporal features captured in the bias. Specifically, the correlation of the monthly time series of ERA5 ranges from 0.90 with CRU‐TS over equatorial EA (EEA) to 0.98 with GPCC over southern EA (SEA) in contrast to that of ERA‐Interim which ranges from 0.84 with CRU‐TS over EEA to 0.93 with CRU‐TS over SEA. However, the wet bias in ERA5 along the Great Rift Valley remained the same as in ERA‐Interim whereas spatial correlation of ERA5 with the two reference rainfall is relatively weaker than that of ERA‐Interim.
Whether increased water‐use efficiency of Picea crassifolia promotes radial growth of trees in the eastern Qilian Mountains
Authors: Wang Kai , Gou Xiaohua , Gao Linlin , Liu Wenhuo , Fan Haowen , Zhang Weiguo , Yang Haijiang 
Published: May 2022

AbstractGlobal change, characterized by elevated atmospheric CO2 concentrations and warming, is profoundly affecting terrestrial forests. However, whether the increasing atmospheric CO2 concentration has a fertilizer effect on tree growth and whether intrinsic water use efficiency (iWUE) promotes tree growth in semi‐arid regions is not entirely clear. In this study, we evaluated the relationships between tree‐ring widths, δ13C values and iWUE of Qinghai Spruce (Picea crassifolia Kom.) in the eastern Qilian Mountains, northwestern China. We found that the iWUE is significantly consistent with the δ13C of rings in the high‐frequency signal, and the relationship between iWUE and tree‐ring width is unstable. The first‐order difference correlation analysis with meteorological data showed that both the iWUE and tree‐ring width were drought‐limited. The radial growth was mainly regulated by water availability in current April and July, while annual variation of iWUE was primarily controlled by that in current July. In the early stage of trees growth, there was a positive relationship between iWUE and radial growth due to the CO2 fertilization. During the 1970s–2000s, the effect of water availability in July on radial growth increases because of the decreased precipitation in July. This has decreased stomatal conductance, intercellular CO2 concentration, carbon uptake and growth, contributing to the negatively significant correlation between tree‐ring widths and iWUE (p < .05). Since the year of 2010, the relationship between the radial growth and iWUE shifted because of the increased precipitation in July. This study provided new insights for whether increased water‐use efficiency enhances tree growth under semixeric conditions.
A determination of season shifting across Turkey in the period 1965–2020
Authors: Aksu Hakan 
Published: May 2022

AbstractSignificant changes in the onset, length and thermal characteristics of seasons have been reported all over the globe in recent decades; however, the spatiotemporal changes of seasonal characteristics in Turkey have received little attention in relation to seasons delineation. In this study, the changes in the characteristics of Turkish seasons have been examined from 1965 to 2020 by considering the daily average temperature data obtained from 65 meteorological stations. A nonstatic definition of season onset was used to delineate the seasons. The study also presents the response of seasons timing and thermal characteristics affected by climate change. All over Turkey, the trend rate for beginning of summer was determined to be 2.1 days·decade−1 from 1965 to 2020, while the beginning of winter has shifted forward at many stations in southeastern Anatolia. All the seasons have experienced increases in average temperatures. The maximum increase was in summer seasons and occurred at up to a rate of 0.7°C·decade−1. There has been almost no change in winter temperatures over the Mediterranean region. Eastern Marmara with the western and middle Black Sea regions experienced an extension of spring as well as a shortening of the autumn season. It was noted that the change in the beginning of summer occurred all over the country. However, the extension of spring and shortening of the autumn season was mainly limited to the western Black Sea regions. The seasons, defined by considering climate change and variability, showed significant trends for length, average temperature and their onset. To the best of the author's knowledge, the delineation of seasons using a dynamic approach is the first attempt of its kind in this study area.
Denoising Raman spectra using fully convolutional encoder–decoder network
Authors: Loc Irem , Kecoglu Ibrahim , Unlu Mehmet Burcin , Parlatan Ugur 
Published: May 2022

AbstractRaman spectroscopy is a vibrational method that gives molecular information rapidly and non‐invasively. Despite its advantages, the weak intensity of Raman spectroscopy leads to low‐quality signals, particularly with tissue samples. The requirement of high exposure times makes Raman a time‐consuming process and diminishes its non‐invasive property while studying living tissues. Novel denoising techniques using convolutional neural networks (CNN) have achieved remarkable results in image processing. Here, we propose a similar approach for noise reduction for the Raman spectra acquired with 10
lower exposure times. In this work, we developed fully convolutional encoder‐decoder architecture (FCED) and trained them with noisy Raman signals. The results demonstrate that our model is superior (p value < 0.0001) to the conventional denoising techniques such as the Savitzky‐Golay filter and wavelet denoising. Improvement in the signal‐to‐noise ratio values ranges from 20% to 80%, depending on the initial signal‐to‐noise ratio. Thus, we proved that tissue analysis could be done in a shorter time without any need for instrumental enhancement.