bluuebunny/crossref_metadata_2025_split huggingface dataset:
Complicações em pacientes internados por COVID-19 com insuficiência cardíaca descompensada
Authors: Santos Gabriela Silva , Santos Gabriel Barbosa Figueira dos , Bispo Laura Dayane Gois , Santos Debora Santana , Tavares Gilberto Andrade , Meneguz-Moreno Rafael Alexandre , Campos Viviane Correia 
Published: August 2022

Objetivo: Analisar o desenvolvimento de complicações durante a internação de pacientes com COVID-19 e IC. Método: Trata-se de um estudo observacional, quantitativo, a partir da revisão dos prontuários dos pacientes internados na Unidade de Doenças Respiratórias (UDR) de um Hospital Universitário do nordeste brasileiro, com RT-PCR reagente para SARS-COV2 e diagnóstico de IC. Resultados: Dos 77 pacientes, 51 (66,2%) apresentavam uma insuficiência cardíaca crônica agudizada (ICCa) enquanto os demais (n = 26; 33,8%) não tinham história de cardiopatia prévia e estavam apresentando o primeiro episódio de insuficiência cardíaca aguda (ICA). Aqueles com a classificação NYHA IV tiveram maior risco de desenvolver choque (p = 0,001), parada cardiorrespiratória (PCR) (p = 0,01), síndrome do desconforto respiratório agudo (SDRA) (p < 0,0001), bacteremia (p = 0,008), hemorragia e dano hepático (p = 0,04) como complicações. A taxa de mortalidade intra-hospitalar foi de 39% (n= 30). Ao analisar a relação entre o tipo de complicação desenvolvida com o desfecho óbito, choque, PCR, SDRA (p < 0,0001), pneumonia (p = 0,009), bacteremia (p = 0,0003), hemorragia, anemia (p = 0,02), arritmia cardíaca (p = 0,03) e dano hepático (p = 0,04) tiveram associação significante. Conclusão: A associação entre IC e COVID-19 na internação leva a uma alta taxa de mortalidade intra-hospitalar. Pacientes com a classe funcional NYHA IV possuem maior risco de desenvolver complicações e óbito durante internação. Além disso, os pacientes com IC e COVID-19 que desenvolvem pneumonia, SDRA, choque, PCR, anemia, hemorragia, arritmia, dano hepático e/ou bacteremia possuem maior taxa de mortalidade.
Storm politics: how governmental response to natural disasters is influenced by capacity
Authors: Menezes Aline Brêtas de 
Published: August 2022

Despite the remarkable gains in performance research, public administration field still lacks more empirical analysis of the organizational capacity-government performance relationship and objective measures of organizational capacity. We shed light on the role how capacity enhances performance. By using secondary longitudinal data, we focus on the actions taken by 5,570 Brazilian municipalities to prevent or reduce damage caused by natural disasters. Droughts represent a significant impact on the environment of the region, affect local economy and bring misery to the population. Our hypotheses investigate whether mayors' competence and/or municipal capabilities influence the governmental response to prevent or reduce damage caused by natural disasters. Results provide support for all three hypotheses meaning that when considering both internal dimensions of capacity, it is possible to predict the probability of a municipality adopts actions pro-environment to prevent or reduce damage caused by droughts. Although government faces various constraints, we contribute to investigate subnational organizational capacity as an input to performance of municipalities giving research a more fulsome assessment of government quality.
Utilização de lipossomas no diagnóstico e tratamento do câncer de pele não melanoma: uma revisão integrativa
Authors: Mendes Ana Victória da Silva , Santos Andressa Amorim dos , Pinheiro Clailson da Silva , Lopes Talissa Brenda de Castro , Nogueira Maritânia dos Santos , Rolim Hercilia Maria Lins 
Published: August 2022

O câncer de pele não melanoma (CPNM) é o tipo de câncer com maior incidência e tem sido classificado em: carcinoma basocelular (CBC) e carcinoma espinocelular (CEC). O objetivo do presente estudo foi avaliar, por meio de uma revisão bibliográfica integrativa, a utilização de lipossomas no diagnóstico e tratamento de CPNM. A estratégia de busca dos artigos científicos foi realizada através de uma investigação nas bases de dados Scopus, Pubmed e Web Of Science, acessando através do Portal Periódicos Capes, utilizando os descritores em inglês “Liposomes” AND “non-melanoma” AND “skin” AND “cancer” AND “(treatment OR diagnosis)”. Para auxiliar o processo de análise dos artigos, utilizou-se a plataforma Rayyan. Após análise, 7 publicações foram selecionadas para compor essa revisão, identificando: títulos, autores, objetivos, principais resultados, conclusões e temas abordados nos estudos. Observou-se que a maioria dos eixos temáticos abordaram a utilização de sistemas lipossomais para a potencialização de drogas com capacidade antitumoral. Os demais artigos discorriam sobre a utilização na detecção e diagnóstico das lesões associadas ao Câncer de Pele Não Melanoma e, também, a aplicação de nanocarreadores em terapias anticâncer, sobretudo na terapia fotodinâmica. Baseado nisso, concluiu-se que os lipossomas possuem uma aplicação versátil no CPNM, indo do tratamento ao diagnóstico, no entanto, as pesquisas acerca da aplicação voltada para esse tema, são escassas e recentes. Dessa forma, esta revisão é de extrema relevância para que se possa direcionar a elaboração de novos estudos que visem aprimorar técnicas já mencionadas e desenvolver novas pesquisas acerca do tema.
Ensino de Química Orgânica por meio de atividades experimentais: Análise baseada na perspectiva dos professores de Química do Ensino Médio de Confresa/MT
Authors: Maciel Aldenair Gomes , Leão Marcelo Franco 
Published: August 2022

O presente estudo teve como objetivo analisar as práticas experimentais utilizadas no ensino de Química Orgânica por professores do Ensino Médio da cidade de Confresa/MT. Essa pesquisa de campo, de natureza básica, descritiva e exploratória, cuja abordagem foi qualitativa, foi desenvolvida durante o segundo semestre de 2021. Os sujeitos investigados foram 9 professores de Química do Ensino Médio que atuam nessa cidade. Para coletar dados foi utilizado um questionário, constituído por 11 questões abertas. As respostas foram organizadas em quatro categorias de análise: Atividades experimentais e conteúdos abordados; Como desenvolver os experimentos em aula; Contribuições para o aprendizado dos alunos; e O uso de Materiais Alternativos. Com a realização desse estudo foi possível verificar que a experimentação no ensino é bastante usada pelos professores, trazendo assim uma ótima assimilação com o cotidiano dos alunos. Também revelou que as atividades experimentais são, na percepção desses professores, de suma importância para se ensinar Química, pois ela traz sentido de forma concreta a tudo o que está sendo estudado. Dessa forma, constatou-se que a utilização da experimentação no ensino de Química, especificamente abordando assuntos da Química Orgânica, é viável e necessária para ser desenvolvida em sala de aula, mesmo que seja por meio de materiais de fácil acesso, ou seja, materiais alternativos. Logo, essa metodologia de ensino, além de aproximar teoria e prática em sua essência, proporciona um ensino envolvente e uma aprendizagem significativa, motivando os alunos para que desenvolvam atitudes e valores, na construção e reconstrução de significados para os conceitos científicos, oportunizando a compreensão e interpretação dos fenômenos da natureza.
THE EFFECT OF MASSAGE EFFLEURAGE WITH LAVENDER AROMATHERAPY ON THE INTENSITY OF DYMENORORE PAIN IN ADOLESCENT WOMEN IN THE PABELAN HEALTH CENTER
Authors: Hudhariani Rose Nur , Yunani Yunani 
Published: August 2022

ABSTRACT

The incidence of dysmenorrhea in the world is very large, at least 45-90% of women experience dysmenorrhea during the reproductive years. Several self-care measures can be taken for the management of menstrual pain. One of the non-pharmacological methods to reduce pain intensity can be done by using effleurage massage and lavender aromatherapy.
This study aims to find out the effect of massage effleurage combination of lavender aromatherapy on the intensity of dysmenorrhea pain in adolescent women in the working area of Pabelan Health Center.
The research method used is quantitative using a quasi-experimental approach. The sampling technique used non-probability sampling/non-random, the number of samples was 28 people according to the specified criteria. Massage effleurage combined with lavender aromatherapy for 10 minutes. The act of giving 3 drops of lavender aromatherapy into 40 ml of water through a diffuser that will be turned on during massage effleurage therapy
The result of this study was that there was a difference in disminore pain in adolescent women before and after the intervention of Massage Effleurage therapy combined with lavender aromatherapy in the working area of Pabelan Health Center of Semarang Regency (P-value = 0.000).

Keywords: Dysmenorrhea, Lavender Aromatherapy, Massage Effleurage,
THE RELATIONSHIP BETWEEN KNOWLEDGE OF PREGNANT WOMEN AND FAMILY SUPPORT FOR THE PARTICIPATION OF PREGNANT WOMEN IN TEACHING CLASSES FOR PREGNANT WOMEN IN THE WORK AREA OF UPT PUSKESMAS PANCA MAKMUR
Authors: Jusniar Jusniar , Marfuah Siti 
Published: August 2022

Knowledge is the sensing of object (Arifah E A & Fridayanti W, 2016). Participation is personal involvement (Dwiningrum, 2018). Support is verbal or non-verbal advice, action have emotional benefit. This study aim to show that teaching classes for pregnant women have a good impact on pregnant women, which increase the knowledge and skill of pregnant women in dealing with pregnancy until the parturition process. Teaching class for pregnant women aim to reduce maternal and infant mortality.
This study aim to determine the relationship between knowledge of pregnant women and family support on the participation of pregnant women in the Teaching Class for Pregnant Women in the working area of ​​the Panca Makmur Health Center UPT. This type of research is a quantitative study with a descriptive correlational approach. Normality test was carried out using descriptive analytic with a sample size of 36 so that the significant value of Kolmogorov-Smirnov was selected. So the correlation test use rank spearment
The results showed that the knowledge of pregnant women was not good enough for 4 respondents (11.1%) and 32 respondents (88.8%). Poor family support 19 respondents (52.7%) and good support 17 respondents (47.2 %). Participation of pregnant women in teaching classes for pregnant women is not good 7 respondents (19.4%) and 29 respondents are good (80.6%). The rank spearment test shows that H1 is rejected, meaning that there is no relationship between knowledge of pregnant women and family support on the participation of pregnant women in teaching classes for pregnant women in the working area of ​​UPT Puskesmas Panca Makmur.
Keywords: Knowledge, Support, Participation of pregnant women
Reproductive lifespan in association with risk of hypertension among Chinese postmenopausal women: Results from a large representative nationwide population
Authors: Hu Zhen , Chen Lu , Wang Xin , Zhang Linfeng , Chen Zuo , Zheng Congyi , Cao Xue , Song Yuxin , Zhou Haoqi , Tian Yixin , Cai Jiayin , Huang Yilin , Gu Runqing , Tian Ye , Shao Lan , Wang Zengwu 
Published: August 2022

BackgroundThe association between reproductive lifespan and risk of hypertension among postmenopausal women is unclear.MethodsA total of 94,141 postmenopausal women with a mean age of 64.8 years from the China Hypertension Survey were enrolled at baseline from 2012 to 2015. A standardized questionnaire was used to collect relevant information by well-trained interviewers. Blood pressure and physical examination of the participants were performed by trained medical staff. Logistic regression was used to estimate the odds ratios for hypertension by years of reproductive lifespan.ResultsThe average years of reproductive lifespan in Chinese women was 34.0 years. Women who were longer in reproductive lifespan were more likely to have older age at recruitment, higher body mass index, larger waist circumference, lower mean systolic blood pressure, and higher mean diastolic blood pressure (p &lt; 0.05). After adjustments, odds ratios (95% confidence interval) for hypertension were 1.035 (0.988–1.085), 1.007 (0.966–1.048), 1.000 (reference), 0.932 (0.899–0.967), and 0.953 (0.909–0.997) for those with reproductive lifespan at ≤ 28, 29–31, 32–34 (reference), 35–37, and ≥ 38 years, respectively, with a significantly inverse association was seen in those with reproductive lifespan at 35–37 and ≥ 38 years. The overall risk of hypertension declined with the increase in reproductive lifespan, and the risk of hypertension was reduced by 1.1% for every 1-year increase in the reproductive lifespan (odds ratio, 0.989; 95% confidence interval, 0985–0.994) per year. The negative association between reproductive lifespan and hypertension was evident among age at recruitment groups, body mass index categories, and education levels, with the strongest association among women aged ≥ 70 years. Positive associations between reproductive lifespan and risk of hypertension were evident among women aged &lt; 60 years, and this association was stronger among current alcohol drinkers.ConclusionBased on the large nationally representative sample, Chinese postmenopausal women with a shorter reproductive lifespan have a higher risk of hypertension.
Comprehensive metabolomic characterization of atrial fibrillation
Authors: Lu Chengcan , Liu Chunyan , Mei Di , Yu Mengjie , Bai Jian , Bao Xue , Wang Min , Fu Kejia , Yi Xin , Ge Weihong , Shen Jizhong , Peng Yuzhu , Xu Wei 
Published: August 2022

BackgroundUsing human humoral metabolomic profiling, we can discover the diagnostic biomarkers and pathogenesis of disease. The specific characterization of atrial fibrillation (AF) subtypes with metabolomics may facilitate effective and targeted treatment, especially in early stages.ObjectivesBy investigating disturbed metabolic pathways, we could evaluate the diagnostic value of biomarkers based on metabolomics for different types of AF.MethodsA cohort of 363 patients was enrolled and divided into a discovery and validation set. Patients underwent an electrocardiogram (ECG) for suspected AF. Groups were divided as follows: healthy individuals (Control), suspected AF (Sus-AF), first diagnosed AF (Fir-AF), paroxysmal AF (Par-AF), persistent AF (Per-AF), and AF causing a cardiogenic ischemic stroke (Car-AF). Serum metabolomic profiles were determined by gas chromatography–mass spectrometry (GC-MS) and liquid chromatography–quadrupole time-of-flight mass spectrometry (LC-QTOF-MS). Metabolomic variables were analyzed with clinical information to identify relevant diagnostic biomarkers.ResultsThe metabolic disorders were characterized by 16 cross-comparisons. We focused on comparing all of the types of AF (All-AFs) plus Car-AF vs. Control, All-AFs vs. Car-AF, Par-AF vs. Control, and Par-AF vs. Per-AF. Then, 117 and 94 metabolites were identified by GC/MS and LC-QTOF-MS, respectively. The essential altered metabolic pathways during AF progression included D-glutamine and D-glutamate metabolism, glycerophospholipid metabolism, etc. For differential diagnosis, the area under the curve (AUC) of specific metabolomic biomarkers ranged from 0.8237 to 0.9890 during the discovery phase, and the predictive values in the validation cohort were 78.8–90.2%.ConclusionsSerum metabolomics is a powerful way to identify metabolic disturbances. Differences in small–molecule metabolites may serve as biomarkers for AF onset, progression, and differential diagnosis.
Characteristics, outcomes, and predictors of de novo malignancy after heart transplantation
Authors: Youn Jong-Chan , Kim Darae , Kim In-Cheol , Lee Hye Sun , Choi Jin-Oh , Jeon Eun-Seok , Nishihara Keith , Kransdorf Evan P. , Chang David H. , Kittleson Michelle M. , Patel Jignesh K. , Ramzy Danny , Esmailian Fardad , Kobashigawa Jon A. 
Published: August 2022

BackgroundPost-transplant malignancy (PTM) causes long-term morbidity and mortality in heart transplant (HTx) recipients. However, the detailed characteristics or predictors of PTM are not well-known. We evaluated the incidence, characteristics, long-term outcomes, and predictors of de novo PTM using a single center large-volume database.MethodsWe retrospectively analyzed the types and characteristics of de novo PTM in 989 patients who underwent HTx. Univariate and multivariate logistic regression analyses were used for the PTM prediction model.ResultsTwo hundred and six patients (20.8%) had de novo PTMs (241 cancers) during a median follow-up of 11.5 years. PTM patients were older than non-PTM patients, received immunosuppressive therapy for a longer period, and were more likely to be male and white. Skin cancers were the most frequent types of malignancy (60.6%) followed by prostate (9.5%), lung (7.1%), and breast (4.1%) cancers. Although most cancers (88.8%) were surgically resected at initial presentation, about half (47.3%) recurred or progressed. Patients with skin cancer and non-skin cancer had significantly lower overall survival (P &lt; 0.001) than patients without cancer. Older age (P &lt; 0.001), white race (P = 0.001), and longer time receiving immunosuppressive therapy (P &lt; 0.001) were independent predictors for PTM.ConclusionOlder age, white race, and longer administration of immunosuppressive therapies were independent risk factors for PTM, which was associated with increased mortality. Further research is necessary for the prevention and early detection of PTM in HTx recipients.
Development of a non-contact sleep monitoring system for children
Authors: Kamon Masamitsu , Okada Shima , Furuta Masafumi , Yoshida Koki 
Published: August 2022

Daily monitoring is important, even for healthy children, because sleep plays a critical role in their development and growth. Polysomnography is necessary for sleep monitoring. However, measuring sleep requires specialized equipment and knowledge and is difficult to do at home. In recent years, smartwatches and other devices have been developed to easily measure sleep. However, they cannot measure children's sleep, and contact devices may disturb their sleep.A non-contact method of measuring sleep is the use of video during sleep. This is most suitable for the daily monitoring of children’s sleep, as it is simple and inexpensive. However, the algorithms have been developed only based on adult sleep, whereas children’s sleep is known to differ considerably from that of adults.For this reason, we conducted a non-contact estimation of sleep stages for children using video. The participants were children between the ages of 0–6 years old. We estimated the four stages of sleep using the body movement information calculated from the videos recorded. Six parameters were calculated from body movement information. As children’s sleep is known to change significantly as they grow, estimation was divided into two groups (0–2 and 3–6 years).The results show average estimation accuracies of 46.7 ± 6.6 and 49.0 ± 4.8% and kappa coefficients of 0.24 ± 0.11 and 0.28 ± 0.06 in the age groups of 0–2 and 3–6 years, respectively. This performance is comparable to or better than that reported in previous adult studies.
A comprehensive review of methods based on deep learning for diabetes-related foot ulcers
Authors: Zhang Jianglin , Qiu Yue , Peng Li , Zhou Qiuhong , Wang Zheng , Qi Min 
Published: August 2022

BackgroundDiabetes mellitus (DM) is a chronic disease with hyperglycemia. If not treated in time, it may lead to lower limb amputation. At the initial stage, the detection of diabetes-related foot ulcer (DFU) is very difficult. Deep learning has demonstrated state-of-the-art performance in various fields and has been used to analyze images of DFUs.ObjectiveThis article reviewed current applications of deep learning to the early detection of DFU to avoid limb amputation or infection.MethodsRelevant literature on deep learning models, including in the classification, object detection, and semantic segmentation for images of DFU, published during the past 10 years, were analyzed.ResultsCurrently, the primary uses of deep learning in early DFU detection are related to different algorithms. For classification tasks, improved classification models were all based on convolutional neural networks (CNNs). The model with parallel convolutional layers based on GoogLeNet and the ensemble model outperformed the other models in classification accuracy. For object detection tasks, the models were based on architectures such as faster R-CNN, You-Only-Look-Once (YOLO) v3, YOLO v5, or EfficientDet. The refinements on YOLO v3 models achieved an accuracy of 91.95% and the model with an adaptive faster R-CNN architecture achieved a mean average precision (mAP) of 91.4%, which outperformed the other models. For semantic segmentation tasks, the models were based on architectures such as fully convolutional networks (FCNs), U-Net, V-Net, or SegNet. The model with U-Net outperformed the other models with an accuracy of 94.96%. Taking segmentation tasks as an example, the models were based on architectures such as mask R-CNN. The model with mask R-CNN obtained a precision value of 0.8632 and a mAP of 0.5084.ConclusionAlthough current research is promising in the ability of deep learning to improve a patient’s quality of life, further research is required to better understand the mechanisms of deep learning for DFUs.
A rare case report of multifocal para-aortic and para-vesical paragangliomas
Authors: Xiong San-Chao , Di Xing-Peng , Zhang Meng-Ni , Wu Kan , Li Xiang 
Published: August 2022

BackgroundParagangliomas (PGLs) are uncommon tumors of uncertain malignant potential. Multifocal paragangliomas are scarcely reported in the literature.Case summaryA 25-year-old male patient was reported for the first time with multifocal para-aortic and para-vesical PGLs. The diagnosis was identified by blood catecholamine tests and enhanced CT scan and MIBG scintigraphy. A resection surgery was performed for treatment and the immunochemistry test of the tumors presented the features of PGL.ConclusionA case of multifocal para-aortic and para-vesical PGLs confirmed by the catecholamine test, enhanced CT, and MIBG scintigraphy is presented. The cooperation of experienced surgeons, anesthesiologists, and endocrinologists was critical in treatment.