bluuebunny/crossref_metadata_2025_split huggingface dataset:
Addressing Mental and Social Health in Workers' Compensation
Authors: Ring David 
Published: February 2022

Abstract
Humans interpret and react to symptoms. We only seek care for a symptom when it becomes a concern.1 Variation in symptom intensity and magnitude of capability relates more to unhelpful thoughts, feelings of worry and despair regarding symptoms, and feelings of insecurity around role and livelihood (mental and social health opportunities) than pathophysiology.2 Work claims are meant to address pathology that results from injury. Injuries have predictable recovery trajectories. When the recovery trajectory seems off track, consider pre-existing non-trauma pathology and mental and social health opportunities. Appropriate management of new pathology under the work claim and pre-existing pathology and mental and social health opportunities outside the work claim, along with a supportive environment that anticipates these aspects of normal human illness behavior, can help people get and stay healthy in the context of workers' compensation.
Mars entry navigation under biases based on adaptive Huber divided difference filter
Authors: Xia Yuanqing , Zhu Cui , Cui Pingyuan , Xing Zirui , Dai Li , Wang Liansheng 
Published: February 2022

SummaryTo address the problems of unknown disturbances and measurement outliers at Mars entry phase, three integrated navigation schemes are proposed in this study by complying with divided difference filters, that is, integrated navigation schemes based on the Huber first‐order divided difference filter (HDDF1), adaptive Huber first‐order divided difference filter (AHDDF1), and adaptive Huber second‐order divided difference filter (AHDDF2). The novel versions of predictive state estimation error covariance (PSEEC) and measurement noise covariance (MNC) are deduced by adopting the function of the Huber case to modify the cost function of the standard Kalman filter. To be specific, the HDDF1 is derived by embedding the novel PSEEC and MNC in the general first‐order divided difference filter. To more specifically enhance the performance of the filter under significant biases, an adaptive forgetting factor is introduced in the HDDF1. On that basis, the AHDDF1 is derived. Likewise, the AHDDF2 is yielded. The numerical simulations are presented to verify the effectiveness of the proposed navigation schemes.
A Wearable All‐Gel Multimodal Cutaneous Sensor Enabling Simultaneous Single‐Site Monitoring of Cardiac‐Related Biophysical Signals
Authors: Chun Kyoung‐Yong , Seo Seunghwan , Han Chang‐Soo 
Published: February 2022

AbstractThe human cutaneous sensory organ is a highly evolved biosensor that is efficient, sensitive, selective, and adaptable. Recently, with the development of various materials and structures inspired by sensory organs, artificial cutaneous sensors have been widely studied. In this study, the acquisition of biophysical signals is demonstrated at one point on the body using a wearable all‐gel‐integrated multimodal sensor composed of four element sensors, inspired by the slow/rapid adapting functions of the skin sensory receptors. The gel‐type sensors ensure flexibility, compactness, portability, adherence, and integrity. The wearable all‐gel multimodal sensor is easily attached to the wrist and simultaneously gathers blood pressure (BP), electrocardiogram (ECG), electromyogram (EMG), and mechanomyogram (MMG) signals related to cardiac and muscle health. Human activity causes muscle contraction, which affects blood flow; therefore, the relationship between the muscle and heart is crucial for screening and predicting heart health. Cardiac health is monitored by obtaining the two types of phase time differences (i.e., Δtbe: BP and ECG, Δtem: ECG and MMG) generated during muscle movement. The suggested multimodal sensor has potential applicability in monitoring biophysical conditions and diagnosing cardiac‐related health problems.
WET‐Induced Layered Organohydrogel as Bioinspired “Sticky−Slippy Skin” for Robust Underwater Oil‐Repellency
Authors: Wan Xizi , Jia Lanxin , Liu Xi , Dai Bing , Jiang Lei , Wang Shutao 
Published: February 2022

AbstractUnderwater superoleophobic surfaces featuring anti‐oil‐fouling properties are of great significance in widespread fields. However, their complicated engineering process and weak interfacial adhesion strength with underlying substrates severely hamper these ideal surfaces toward practical applications. Here, a moss‐inspired sticky−slippy skin composed of layered organohydrogel is reported through a one‐step wetting‐enabled‐transfer (WET) strategy, which unprecedentedly integrates robust inherent adhesion with durable anti‐oil‐fouling properties. The sticky organogel layer can be simply attached to various substrates, from metals and plastics to glass, independent of any surface pretreatment. The slippy hydrogel layer enables stable underwater superoleophobicity and ultralow oil adhesion for diverse kinds of oils. The sticky−slippy skin features outstanding comprehensive properties including easy‐pasting, anti‐swelling/anti‐bending, compatibility with commercial adhesives, acid/alkali resistance, environmental friendliness, and substrate universality. The design strategy with integrated functions provides a clue to accelerate the development of bioinspired multifunctional interfacial materials toward real‐world applications.
Stable and Solution‐Processable Cumulenic sp‐Carbon Wires: A New Paradigm for Organic Electronics
Authors: Pecorario Stefano , Scaccabarozzi Alberto D. , Fazzi Daniele , Gutiérrez‐Fernández Edgar , Vurro Vito , Maserati Lorenzo , Jiang Mengting , Losi Tommaso , Sun Bozheng , Tykwinski Rik R. , Casari Carlo S. , Caironi Mario 
Published: February 2022

AbstractSolution‐processed, large‐area, and flexible electronics largely relies on the excellent electronic properties of sp2‐hybridized carbon molecules, either in the form of π‐conjugated small molecules and polymers or graphene and carbon nanotubes. Carbon with sp‐hybridization, the foundation of the elusive allotrope carbyne, offers vast opportunities for functionalized molecules in the form of linear carbon atomic wires (CAWs), with intriguing and even superior predicted electronic properties. While CAWs represent a vibrant field of research, to date, they have only been applied sparingly to molecular devices. The recent observation of the field‐effect in microcrystalline cumulenes suggests their potential applications in solution‐processed thin‐film transistors but concerns surrounding the stability and electronic performance have precluded developments in this direction. In the present study, ideal field‐effect characteristics are demonstrated for solution‐processed thin films of tetraphenyl[3]cumulene, the shortest semiconducting CAW. Films are deposited through a scalable, large‐area, meniscus‐coating technique, providing transistors with hole mobilities in excess of 0.1 cm2 V−1 s−1, as well as promising operational stability under dark conditions. These results offer a solid foundation for the exploitation of a vast class of molecular semiconductors for organic electronics based on sp‐hybridized carbon systems and create a previously unexplored paradigm.
Spatial Separation of Cocatalysts on Z‐Scheme Organic/Inorganic Heterostructure Hollow Spheres for Enhanced Photocatalytic H2 Evolution and In‐Depth Analysis of the Charge‐Transfer Mechanism
Authors: Moon Hyun Sik , Hsiao Kai‐Chi , Wu Ming‐Chung , Yun Yongju , Hsu Yung‐Jung , Yong Kijung 
Published: February 2022

AbstractA Z‐scheme heterojunction with spatially separated cocatalysts is proposed for overcoming fundamental issues in photocatalytic water splitting, such as inefficient light absorption, charge recombination, and sluggish reaction kinetics. For efficient light absorption and interfacial charge separation, Z‐scheme organic/inorganic heterojunction photocatalysts are synthesized by firmly immobilizing ultrathin g‐C3N4 on the surface of TiO2 hollow spheres via electrostatic interactions. Additionally, two cocatalysts, Pt and IrOx, are spatially separated along the Z‐scheme charge‐transfer pathway to enhance surface charge separation and reaction kinetics. The as‐prepared Pt/g‐C3N4/TiO2/IrOx (PCTI) hollow sphere photocatalyst exhibits an exceptional H2 evolution rate of 8.15 mmol h−1 g−1 and a remarkable apparent quantum yield of 24.3% at 330 nm in the presence of 0.5 wt% Pt and 1.2 wt% IrOx cocatalysts on g‐C3N4 and TiO2, respectively. Photoassisted Kelvin probe force microscopy is used to systematically analyze the Z‐scheme charge‐transfer mechanism within PCTI. Furthermore, the benefits of spatially separating cocatalysts in the PCTI system are methodically investigated in comparison to randomly depositing them. This work adequately demonstrates that the combination of a Z‐scheme heterojunction and spatially separated cocatalysts can be a promising strategy for designing high‐performance photocatalytic platforms for solar fuel production.
A Nanostructured Moisture‐Absorbing Gel for Fast and Large‐Scale Passive Dehumidification
Authors: Dai Ming , Zhao Fei , Fan Juanjuan , Li Qing , Yang Ya , Fan Zhuangjun , Ling Shengjie , Yu Haipeng , Liu Shouxin , Li Jian , Chen Wenshuai , Yu Guihua 
Published: February 2022

AbstractDehumidification is significant for environmental sustainability and human health. Traditional dehumidification methods involve significant energy consumption and have negative impact on the environment. The core challenge is to expose hygroscopic surfaces to the air, and appropriately store the captured water and avoid surface inactivation. Here, a nanostructured moisture‐absorbing gel (N‐MAG) for passive dehumidification, which consists of a hydrophilic nanocellulose network functionalized by hygroscopic lithium chloride, is reported. The interconnected nanocellulose can transfer the captured water to the internal space of the bulky N‐MAG, eliminating water accumulation near the surfaces and hence enabling high‐rate moisture absorption. The N‐MAG can reduce the relative humidity from 96.7% to 28.7% in 6 h, even if the space is over 2 × 104 times of its own volume. The condensed water can be completely confined in the N‐MAG, overcoming the problem of environmental pollution. This research brings a new perspective for sustainable humidity management without energy consumption and with positive environmental footprint.
Targeting TFAP2C/PDCD6 Pathway by lncRNA PP7080 Expedites Tumorigenesis and Contributes to an Immunosuppressive Tumor Microenvironment in Non‐Small Cell Lung Cancer
Authors: Zhuo Yue , Hu Wei , Liao Mei‐Juan , Chen Jia‐Hao , Zhang Jian , Wang Juan , Zhang Yu , Zhang Fa‐Xue , Shi Yu‐Fan , Qian Hui‐Ling , Li Shu‐Jun , Sun Cheng‐Cao 
Published: February 2022

AbstractLong noncoding RNAs (lncRNAs) play essential roles in various biological processes. Nevertheless, advance exploration is warranted to elaborate the therapeutic implications and detailed mechanisms of lncRNAs in non‐small cell lung cancer (NSCLC). In the present study, lncRNA PP7080 is found highly expressed and correlated with a poorer prognosis for NSCLC. Knockout of PP7080 diminishes cell proliferation, migration, and invasion, but accelerates cell apoptosis in vitro, and impeded tumor growth in vivo. While elevated PP7080 facilitates cell proliferation, migration and invasion, repressed cell apoptosis in vitro, and accelerated xenograft tumor growth in vivo. Additionally, downregulated DNMT1 is found contributing the higher PP7080 expression via regulation of DNA methylation at PP7080 promoter‐regions in NSCLC. Furthermore, PP7080 directly bound with TFAP2C and facilitated TFAP2C phosphorylation at Ser434 site, and then upregulated PDCD6 expression through binding with its promoters. Furthermore, highly expressed PP7080/PDCD6 correlated with immune‐suppressing tumor microenvironment (TME) in NSCLC. Collectively, the results identified PP7080 mainly localized in the nucleus and functioned its oncogenic role via regulating NSCLC initiation, advancement, and contributing to an immune‐resistant TME through TFAP2C/PP7080/PDCD6 axis, implying PP7080 as a novel therapeutic target for NSCLC.
Older adults and the food security infrastructure
Authors: Balistreri Kelly Stamper 
Published: February 2022

AbstractThis project explores the correlates of state variation in food security using data from the 2008 to 2018 Current Population Survey's Food Security Supplements. The focus is on the relationship between state‐level availability and accessibility of congregate and home‐delivered meal programs, the Supplemental Nutrition Assistance Program, the Senior Farmer's Market Nutrition Program, and the Commodity Supplemental Food Program on food security among lower‐income households headed by older adults (ages 60 and up). Results show evidence that a senior‐specific state‐level food security infrastructure plays a role in the food security status of households headed by older adults.
Cereal rye cover crop terminated at crop planting reduces early‐season weed density and biomass in Wisconsin corn–soybean production
Authors: Grint Kolby R. , Arneson Nicholas J. , Oliveira Maxwel Coura , Smith Daniel H. , Werle Rodrigo 
Published: February 2022

AbstractA fall‐established cereal rye (Secale cereale L.) cover crop has potential to provide weed suppression in fields that will be planted with corn (Zea mays L.) and/or soybean [Glycine max (L.) Merr.], reducing the selection pressure for herbicide resistance as part of an integrated weed management approach. However, biomass from an overwintering cover crop can be limited in areas with prolonged cool‐spring growing conditions, like in the Upper Midwest region of the United States. This study was conducted to determine if a cereal rye cover crop grown in Wisconsin and terminated at the time of crop planting could provide effective levels of early‐season weed suppression in corn–soybean systems practicing no‐till soil management. Cover crop biomass, weed biomass, and weed density were assessed at two Wisconsin locations (eight site‐crop‐years total; four site‐years of each corn and soybean) in 2019 and 2020. Cereal rye biomass production at the time of crop planting ranged from 290–1,480 kg ha–1. Overall, no‐till management with a cover crop reduced weed density by 31% and reduced weed biomass by 61% compared with no‐till without a cover crop. These results indicate that the use of a cereal rye cover crop in the Upper Midwest has potential to reduce the exclusive reliance on spring burndown herbicides in no‐till, but limited spring cover crop biomass in this region may diminish the weed‐suppressive effects from this management practice compared with other parts of the United States where higher amounts of cover crop biomass can be achieved at crop planting time.
Genetic Architecture of Stroke of Undetermined Source: Overlap with Known Stroke Etiologies and Associations with Modifiable Risk Factors
Authors: Georgakis Marios K. , Parodi Livia , Frerich Simon , Mayerhofer Ernst , Tsivgoulis Georgios , Pirruccello James P. , Slowik Agnieszka , Rundek Tatjana , Malik Rainer , Dichgans Martin , Rosand Jonathan , Anderson Christopher D. ,   NINDS Stroke Genetics Network (SiGN)
Published: February 2022

ObjectiveIschemic stroke etiology remains undetermined in 30% of cases. We explored the genetic architecture of stroke classified as undetermined to test if mechanisms and risk factors underlying large‐artery atherosclerotic (LAAS), cardioembolic (CES), and small‐vessel stroke (SVS) contribute to its pathogenesis.MethodsWe analyzed genome‐wide data from 16,851 ischemic stroke cases and 32,473 controls. Using polygenic risk scores for LAAS, CES, and SVS, we assessed the genetic overlap with stroke of undetermined source and used pairwise genomewide association study (GWAS‐PW) to search for shared loci. We then applied Mendelian randomization (MR) to identify potentially causal risk factors of stroke of undetermined source.ResultsGenetic risk for LAS, CES, and SVS was associated with stroke of undetermined source pointing to overlap in their genetic architecture. Pairwise analyses revealed 19 shared loci with LAAS, 2 with CES, and 5 with SVS that have been implicated in atherosclerosis‐related phenotypes. Genetic liability to both carotid atherosclerosis and atrial fibrillation was associated with stroke of undetermined source, but the association with atrial fibrillation was attenuated after excluding cases with incomplete diagnostic workup. MR analyses showed effects of genetically determinants of blood pressure, diabetes, waist‐to‐hip ratio, inflammatory pathways (IL‐6 signaling, MCP‐1/CCL2 levels), and factor XI levels on stroke of undetermined source.InterpretationStroke of undetermined source shares genetic and vascular risk factors with other stroke subtypes, especially LAAS, thus highlighting the diagnostic limitations of current subtyping approaches. The potentially causal associations with carotid atherosclerosis and atherosclerotic risk factors might have implications for prevention strategies targeting these mechanisms. ANN NEUROL 2022;91:640–651
Ein dual‐responsives pH‐ und lichtschaltbares Tensid mit einer Spiropyran‐Einheit: Untersuchungen zum Schaltmechanismus und Anwendung zur Steuerung von Emulsionsstabilitäten
Authors: Reifarth Martin , Bekir Marek , Bapolisi Alain M. , Titov Evgenii , Nußhardt Fabian , Nowaczyk Julius , Grigoriev Dmitry , Sharma Anjali , Saalfrank Peter , Santer Svetlana , Hartlieb Matthias , Böker Alexander 
Published: February 2022

AbstractEin kationisches Tensid mit einer Spiropyran‐Einheit wurde hergestellt, dessen oberflächenaktives Verhalten in dual‐responsiver Weise einstellbar ist. Der Schaltmechanismus des Tensids beruht auf der umkehrbaren Umwandlung des nichtionischen Spiropyrans (SP) zu einer ionischen Merocyaninform (MC/H+), die über eine Änderung des pH‐Wertes der Lösung oder durch Einstrahlung von Licht mit passender Wellenlänge ausgelöst werden kann. Das entsprechende pH‐abhängige photoaktive Verhalten lässt sich so zusammenfassen, dass im Sauren ein ausgeprägter Unterschied zwischen der Oberflächenaktivität beider Formen des Tensids besteht, während dieses Verhalten im neutralen pH‐Bereich unterdrückt ist. Die zugrundeliegenden Prozesse werden vertieft untersucht und eine thermodynamische Erklärung, der eine Verknüpfung aus theoretischen Betrachtungen und experimentellen Ergebnissen zu Grunde liegt, wird gegeben. Das komplexe stimuli‐responsive Verhalten ermöglicht einen gesteuerten Eingriff in kolloidale Systeme. Mithin wird der pH‐abhängige Manipulation einer durch das Tensid stabilisierten Öl‐in‐Wasser‐Emulsion gezeigt, die die vorliegende Studie um eine Anwendung ergänzt.
Rhodaelektro‐katalysierte peri‐selektive direkte Alkenylierungen mit schwacher O‐Koordination ermöglicht durch die Wasserstoffbildungsreaktion (HER)
Authors: Sadowski Bartłomiej , Yuan Binbin , Lin Zhipeng , Ackermann Lutz 
Published: February 2022

AbstractDirekte C−H‐Funktionalisierungen durch Elektrokatalyse werden dominiert durch die Verwendung stark koordinierender N(sp2)‐dirigierender Gruppen. Im Gegensatz dazu sind direkte elektrokatalytische Transformationen schwach koordinierender Phenole weitgehend unbekannt. Vor diesem Hintergrund wurden elektrooxidative peri‐C−H‐Alkenylierungen anspruchsvoller 1‐Naphthole durch die vielseitige Rhodium(III)‐Katalyse mit nutzerfreundlicher galvanostatischer Elektrolyse erreicht. Für die Rhodaelektrokatalyse wurden leicht verfügbare Alkene und ein protisches Reaktionsmedium verwendet. Die Methode zeichnet sich durch eine große Anwendungsbreite, eine gute Toleranz gegenüber funktionellen Gruppen und eine hohe Positions‐ und Stereoselektivität aus. Die Strategie wurde erfolgreich auf hochwertige, stickstoffhaltige Heterocyclen angewandt, wodurch ein direkter Zugang zu ungewöhnlichen heterocyclischen Motiven auf der Grundlage des Dihydropyranochinolingerüsts geschaffen wurde.
Out‐of‐Equilibrium Self‐Replication Allows Selection for Dynamic Kinetic Stability in a System of Competing Replicators
Authors: Liu Bin , Wu Juntian , Geerts Marc , Markovitch Omer , Pappas Charalampos G. , Liu Kai , Otto Sijbren 
Published: February 2022

AbstractAmong the key characteristics of living systems are their ability to self‐replicate and the fact that they exist in an open system away from equilibrium. Herein, we show how the outcome of the competition between two self‐replicators, differing in size and building block composition, is different depending on whether the experiments are conducted in a closed vial or in an open and out‐of‐equilibrium replication–destruction regime. In the closed system, the slower replicator eventually prevails over the faster competitor. In a replication‐destruction regime, implemented through a flow system, the outcome of the competition is reversed and the faster replicator dominates. The interpretation of the experimental observations is supported by a mass‐action‐kinetics model. These results represent one of the few experimental manifestations of selection among competing self‐replicators based on dynamic kinetic stability and pave the way towards Darwinian evolution of abiotic systems.
Sulfamide: A Promising Deep‐Ultraviolet Nonlinear Optical Crystal Assembled from Polar Covalent [SO2(NH2)2] Tetrahedra
Authors: Tian Haotian , Ye Ning , Luo Min 
Published: February 2022

AbstractFor the first time, the polar covalent tetrahedron [SO2(NH2)2] is revealed as a new deep‐ultraviolet (DUV) nonlinear optical (NLO)‐active unit according to theoretical calculations. Furthermore, sulfamide consisting of polar [SO2(NH2)2] units was confirmed as an excellent candidate as a DUV NLO crystal. Sulfamide provides the optimal balance between composition, structure, and properties, in addition to a very short absorption of 160 nm. It achieves multiple optical performance records for non‐π‐conjugated DUV NLO materials, including the strongest second harmonic generation (SHG) efficiency (about 4 times that of KDP), the largest birefringence (obv.: 0.07@589.3 nm) and the shortest SHG wavelength predicted as 188 nm.
Iridium‐Catalyzed Regiodivergent and Enantioselective Hydroalkynylation of Unactivated 1,1‐Disubstituted Alkenes
Authors: Wang Zi‐Xuan , Li Bi‐Jie 
Published: February 2022

AbstractCatalytic enantioselective functionalization of unactivated 1,1‐disubstituted alkenes is challenging due to the difficulty to discriminate the enantiotopic faces. Enantioselective hydrofunctionalization of unactivated 1,1‐disubstituted alkenes with tunable Markovnikov and anti‐Markovnikov selectivity remains elusive. We report here an amide‐directed, regiodivergent and enantioselective hydroalkynylation of unactivated alkenes. The regioselectivity can be readily tuned by the choice of a proper ligand. Catalytic alkynylations occurred with tunable Markovnikov and anti‐Markovnikov selectivity to afford products containing acyclic tertiary or quaternary stereocenters β to an amide. Combining a sequence of alkene isomerization and regioselective hydroalkynylation, we further realized an iridium‐catalyzed formal asymmetric conjugated alkynylation of β,β‐disubstituted α,β‐unsaturated amides. Computational studies suggest that the regioselectivity is dictated by the ligand structures.