bluuebunny/crossref_metadata_2025_split huggingface dataset:
Information asymmetry, east–west cultural differences, and divergence in investor reactions
Authors: Lee Seungho , Walker Thomas , Zhang Aoran , Zhao Yunfei 
Published: July 2022

AbstractThis paper investigates the divergence in investor behaviour between the United States and China following the abolition of the Chinese presidential term limit in 2018, which may, in part, have reflected the heterogeneous opinions expressed in public online media regarding this event. Compared with Chinese investors, the sentiment among US investors was considerably more pessimistic. Accordingly, we find that Chinese companies listed in the United States significantly underperformed relative to a sample of propensity score‐matched firms listed in China. Additionally, we find that the political connectedness of firms to the Chinese government strongly influenced the stock prices of US‐listed Chinese firms.
Mapping of instruments in Japanese for measuring evidence‐based practice among clinical nurses: A scoping review
Authors: Tomotaki Ai , Morioka Noriko , Tsuda Yasunobu 
Published: July 2022

AbstractAimsThis work aims to map instruments available in Japanese that have been assessed for reliability or validity for measuring evidence‐based practice (EBP) among clinical nurses.BackgroundAs EBP competencies comprise various domains, many EBP instruments have been developed. However, instruments available in Japanese for measuring EBP have not been reported systematically.DesignWe conducted a scoping review.Data sourcesTwo different bibliography databases were searched to identify EBP instruments published until 2019: ICHUSHI (for Japanese articles) and PubMed.Review methodsAfter relevant studies were screened and identified, study profile characteristics were extracted to identify EBP instruments in Japanese, and the quality of methodology for developing such instruments was evaluated. This information was recorded and the characteristics were descriptively summarized.ResultsNinety potentially relevant articles were identified, of which seven articles and nine instruments were included in this review. All instruments were based on self‐reported self‐efficacy and attitudes. Few Japanese instruments included all the steps required for EBP. The overall reporting quality of each instrument was low.ConclusionsEBP instruments available in Japanese are extremely scarce. The study results show that it is difficult to measure the various aspects of EBP with the existing instruments.
Demand information sharing of fresh produce supply chain considering competing suppliers’ freshness‐keeping effort
Authors: Chen Zhenjiang , Dan Bin , Ma Songxuan , Tian Yu 
Published: July 2022

AbstractThis paper considers a fresh produce supply chain in which a retailer sources alternative produce from two competing suppliers. The suppliers make efforts to preserve product freshness, while the retailer, with demand forecast information, can share it with none, one or both of the suppliers strategically. By constructing a multistage game model, the optimal demand information sharing strategy in the supply chain is explored. The results show that the retailer has the willingness to disclose demand information only when the freshness elasticity is high. Significantly, with the improvement of the freshness elasticity, the retailer will transform from sharing information with both suppliers to one supplier. The suppliers are always willing to accept the information disclosed by the retailer. However, complete transparency of demand information may hurt the supply chain under certain conditions. To improve the supply chain performance, the retailer can charge both suppliers for information fees and adjust from sharing information with no suppliers to both suppliers with a relatively low freshness elasticity. Conversely, the retailer can change from sharing information with both suppliers to sharing information with one supplier through a charging contract with a relatively high freshness elasticity.
Oral characteristics in adult individuals with periodontal Ehlers‐Danlos syndrome
Authors: Lepperdinger Ulrike , Angwin Chloe , Milnes Di , Sobey Glenda , Ghali Neeti , Johnson Diana , Brady Angela F. , Kammin Tammy , Bowen Jessica M. , Gröbner Rebekka , Lundberg Pernilla , Scott James , Zschocke Johannes , van Dijk Fleur S. , Kapferer‐Seebacher Ines 
Published: July 2022

AbstractAimPeriodontal Ehlers‐Danlos syndrome (pEDS) is a monogenic type of Ehlers‐Danlos syndrome characterized by periodontal destruction at a young age. The present study aimed to document the oral phenotype of pEDS based on prospective clinical investigations.Materials and MethodsThirty‐five adult individuals from 13 families with a clinically and genetically confirmed diagnosis of pEDS underwent a systematic oral assessment.ResultsPeriodontitis stage 3 or 4 or edentulism due to periodontal destruction were diagnosed in 94% of the individuals. First permanent tooth loss was reported at the age of 21.5 years (median; range 13–43 years). Deep periodontal pockets were infrequent, with 94% measuring <4 mm. However, there was increased clinical attachment loss (CAL) averaging 8 mm (range 4–13 mm), and the probability of being edentate between the age of 35 and 44 years was 28–47% compared with less than 0.25% of the general population. Radiographic anomalous findings were only found in a portion of subjects and consisted of fused roots of maxillary second molars (81%), root hypoplasia (57%), taurodontism (26%) and tooth rotation of premolars (67%). As such, radiographic findings are not considered common characteristics of pEDS.ConclusionsCharacteristic oral traits of pEDS in adults are severe CAL with shallow probing depths and marked gingival recession. This is complemented by a lack of attached gingiva. These indications need to be paralleled by genetic analyses to diagnose pEDS unambiguously.
Comparative analysis of bacterial communities in olive psyllids, Euphyllura straminea and Euphyllura pakistanica expose proteobacteria dominance
Authors: Fami‐Tafreshi Tahereh , Askarianzadeh Alireza , Saeedizadeh Ayatolla , Karamipour Naeime , Mehrabadi Mohammad 
Published: July 2022

AbstractInsect–bacteria symbiont associations can be found in almost all insect orders which supply an array of physiological and ecological benefits to the host insect. Plant sap‐feeding insects, including psyllids, have developed symbiotic relationships with a variety of bacteria to compensate nitrogen‐poor diets. In this study, we determined the bacterial composition of two olive psyllid pest species, Euphyllura straminea and Euphyllura pakistanica (Hemiptera: Aphalaridae), using 16S rRNA gene sequence and qPCR analyses. Proteobacteria, including Alphaproteobacteria, Gammaproteobacteria and Betaproteobacteria, composed the primary bacterial structures of the psyllids. Alphaproteobacteria were the dominant bacterial group in E. straminea, while Gammaproteobacteria composed the main portion of the bacterial structure in E. pakistanica. The primary endosymbiont, Carsonella, was detected in both psyllids and Arsenophonus with high prevalence was the main secondary endosymbiont. Interestingly, we observed high titres of Wolbachia in E. straminea compared with E. pakistanica, which revealed a negative correlation between Wolbachia and Carsonella and Arsenophonus titres. Our results show that the limited core microbiota of olive psyllids is similar while the abundance of each bacterial symbiont can vary in different species. A possible role of Wolbachia in modulating bacterial composition in the psyllids was also suggested. There is the potential to utilize symbionts for developing pest control strategies by reducing the insect host's fitness such as targeting essential endosymbionts, transferring symbionts between species and parthenogenesis. Our results can be used as a basis for further research towards the implementation of novel strategies in symbiont‐based biological control of the olive psyllids.
Development and characterization of monoclonal antibodies specific for cyprinid herpesvirus 2
Authors: Zhao Lupin , Gao Wa , zheng Yihua , Lu Liqun , Li Qiang , Jiang Yousheng 
Published: July 2022

AbstractInfections of Cyprinid herpesvirus 2 in goldfish and farmed crucian carp (Carassius auratus gibelio) are still an urgent problem worldwide. Detection and prevention are necessary for the control of haematopoietic necrosis disease caused by CyHV‐2. Although many sensitive molecular diagnostic methods have been developed, effective immunodiagnosis and neutralization approaches based on monoclonal antibodies (MAbs) against CyHV‐2 are still important to CyHV‐2 study. In this experiment, purified CyHV‐2 was used as antigens to produce monoclonal antibodies (Mabs). Six Mabs bound to different proteins were selected by Dot‐blot screening and Western‐blot analysis, and no one had cross‐reactivity with closely related koi herpesvirus. Among them, Mabs 2E1‐B10, 1F5‐A3 and 4C4‐A7 belonged to IgG1 isotype, while other three Mabs 3G9‐B11, 3B4‐G5 and 4F4‐B7 belonged to IgM isotype. These six Mabs all could specifically detect CyHV‐2 in CyHV‐2 infected caudal fin of Carassius auratus gibelio (GiCF) cells by immunofluorescence assays. Then, the neutralization ability was tested in vitro, and the result showed that all six Mabs can attenuate CPE by CyHV‐2 in vitro among which 2E1‐B10 had the best neutralization ability. The virus proteins recognized by these six Mabs were identified by mass spectrometry identification, and the result showed they probably were ORF88, ORF55R, ORF115 and ORF151R. This study is the first to prepare Mabs by purifying CyHV‐2, which will provide a practical basis for the in‐depth study of CyHV‐2 virus.
Improving salt diffusion by ultrasound application during wet salting of pork meat: A mathematical modeling approach
Authors: Sanches Marcio Augusto Ribeiro , Lapinskas Nicholas Matheus , Barretto Tiago Luis , da Silva‐Barretto Andrea Carla , Telis‐Romero Javier 
Published: July 2022

AbstractThe objectives of this research were to evaluate the influence of ultrasound (US; power of 600 W; frequency of 20 kHz), and salt concentration (SC) in brine (50 and 100 g of salt·L−1 of water) on salt gain (SG) in salted pork meat and to investigate the applicability of mathematical models to simulate SG. Four treatments were tested: T50SB, static brine with 50 g of salt·L−1 of water; T100SB, static brine with 100 g of salt·L−1 of water; T50US, US‐assisted brine with 50 g of salt·L−1 of water; T100US, US‐assisted brine with 100 g of salt·L−1 of water. After wet salting, the NaCl content was determined by the Mohr method. Five mathematical models (Azuara; Z and L; Simplified Fick Equation; Weibull; Diffusive) were tested to describe SG. US‐assisted brine and increasing SC in the brine increased (p < .05) the NaCl content in the salted meat. The salt diffusion coefficients also increased (p < .05) as a result of the increase in the SC in the brine and by the application of US (TM). All models tested showed predictability of experimental data and confirmed that US accelerated the SG during wet salting. The Azuara model presented the highest coefficients of determination (R2) and was chosen to predict the experimental data due to its best fit and because it has a simple mathematical solution, also enabling the prediction of equilibrium conditions. Therefore, US‐assisted brine is a technology that can shorten the salting time and improve the salt diffusion in pork meat and the Azuara model can be used to simulate wet salting processes.Practical ApplicationsUltrasound is an emerging technology that has shown promising results in the processing of meat and meat products. This study showed that ultrasound‐assisted brine of pork meat improves SG, increasing the salt diffusion coefficient in salted meat. Therefore, ultrasound‐assisted brine has the potential to shorten salting time in the industrial processing of pork meat. The Azuara model successfully described the kinetic parameters of the process and can be used to simulate the static and ultrasound‐assisted brine process.
Nipple ulcers of the nipple retractor technique to correct inverted nipples: A retrospective multivariate analysis
Authors: Cao Hairu , Wang Hayson Chenyu , Ting Wenyun 
Published: July 2022

AbstractBackgroundA simple procedure using a nipple retractor to correct inverted nipples has been applied in clinical practice with stable and satisfactory aesthetic outcomes. Nipple ulceration and necrosis are rare and severe, with the causes unclear.ObjectiveThis study aimed to investigate the risk factors for the development of nipple ulcers in the nipple retractor technique.MethodsA retrospective study was conducted on inverted nipple patients between January 2012 and September 2021. Clinical information, including baseline patient demographics, reproductive history, smoking, previous treatment, nipple inversion grades, nipple size, areola size, blood flow perfusion, and ulcer development, was collected.ResultsTwenty‐five female patients with 44 inverted nipples were enrolled. Nipple ulcers were present in seven patients, four of whom were bilateral. Logistic regression analysis showed nipple inversion grades (Z = 2.105, OR 7.005, 95% CI: 1.144–42.898, p = 0.035) and relative perfusion of nipples (Z = −2.337, OR 0.969, 95% CI: 0.944–0.995, p = 0.019) were significantly associated with ulceration. The structural equation model demonstrated the interaction of related factors: nipple inversion grades increased by 0.411 points for ulcers (p = 0.004), while relative perfusion of nipples decreased by 0.647 points for ulcers (p < 0.001).ConclusionPreoperative nipple inversion severity and post‐operative nipple blood supply may be the risk factors for nipple ulcer development in the nipple retractor technique.
Trauma exposure and short‐term volitional personality trait change
Authors: Blackie Laura E. R. , Hudson Nathan W. 
Published: July 2022

AbstractObjectiveResearch into post‐traumatic growth (PTG) finds individuals report positive changes in their identity, relationships, and worldviews after trauma. In a pre‐registered 16‐week longitudinal study, we examined trait change after recent trauma exposure to test an operationalization of PTG as positive personality change. We examined the influence of intrapersonal and social factors including motivation to change traits, perceived social support, and event centrality.MethodParticipants (n = 1004) reported on trauma exposure in past 1‐month, centrality of each traumatic event, and social support. Participants with trauma exposure (n = 146) and a matched control group reported on their traits in 8 waves at 2‐week intervals, and motivation to change traits in 3 waves.ResultsAlthough some trait change was observed, it was not consistent with PTG. We found agreeableness declined in the trauma relative to the control group among participants who did not want to change in this trait. Conscientiousness declined for individuals with highly central traumas. Social support predicted increases in emotional stability, conscientiousness, and openness but only for individuals in the control group.ConclusionsWe discuss the value of defining PTG as positive trait change and suggest future directions including assessment of facet‐level changes and ideographic methods.
Evaluation of symmetric dimethylarginine in cats with acute kidney injury and chronic kidney disease
Authors: Loane Samantha C. , Thomson James M. , Williams Timothy L. , McCallum Katie E. 
Published: July 2022

AbstractBackgroundSerum symmetric dimethylarginine (SDMA) concentrations are considered a biomarker for renal dysfunction in dogs and humans with acute kidney injury (AKI). No studies have assessed SDMA in cats with AKI.Hypothesis/ObjectivesSDMA correctly identifies cats with azotemic AKI.AnimalsFifteen control cats, 22 with novel AKI, 13 with acute on chronic‐AKI (AoC) and 19 with chronic kidney disease (CKD).MethodsRetrospective study. Cats with azotemia (serum creatinine concentrations >1.7 mg/dL) were defined as having AKI or CKD based on history, clinical signs, clinicopathological findings and diagnostic imaging, and classified using the International Renal Interest Society (IRIS) grading/staging systems. Serum SDMA concentrations were compared between groups with nonparametric methods, and correlations assessed using Spearman's correlation coefficient. Data are presented as median [range].ResultsSDMA concentrations were 11 (8‐21) μg/dL, 36 (9‐170)μg/dL, 33 (22‐75) μg/dL and 25 (12‐69) μg/dL in control, novel AKI, AoC and CKD cats. SDMA concentrations were significantly higher in cats with novel AKI (P < .001), AoC (P < .001) and CKD (P < .01) compared to controls. SDMA concentrations were significantly higher in cats with more advanced AKI (IRIS grade IV‐V) compared to less severe AKI (IRIS grade II). Serum creatinine and SDMA concentrations had a significant correlation in cats with novel AKI (rs = 0.826, n = 22; P < .001) and a significant correlation when all cats across all 4 groups were considered together (rs = 0.837, n = 69; P < .001).Conclusions and Clinical ImportanceSerum SDMA concentrations are elevated in cats with established AKI (novel and AoC) and CKD, providing evidence for use of SDMA as a biomarker for AKI in cats.
Impact of routine reporting of estimated glomerular filtration rate using the European Kidney Function Consortium and Chronic Kidney Disease Epidemiology Collaboration equations in a Western Australian community population
Authors: Napier Kathryn , Lim David , Thomas Elizabeth , Boyd James , Chakera Aron , Williamson James , Betts Kim , Manuel Justin , Tuando Teodulo Rey , Robinson Suzanne 
Published: July 2022

AbstractAimIn 2020, the European Kidney Function Consortium (EKFC) published a new creatinine‐based equation to estimate glomerular filtration rate (eGFR) to overcome known limitations in existing equations. The aim of this study is to model the potential impact on service referral and health expenditure of routine reporting of eGFR using the EKFC equation as compared to the CKD‐EPI equation in a Western Australian population.MethodseGFR was calculated for 760 614 patients with 2 368 234 creatinine results using the CKD‐EPI and EKFC formulas. Patients were grouped into a CKD cohort if they had at least two eGFR results of <60 ml/min/1.73 m2 from tests at least 90 days apart. The impact of each equation on the reclassification of CKD stages, CKD cohort classification, the rate of change in eGFR and direct health costs were assessed.ResultsAbout 90.66% of patients had a lower eGFR when calculated using the EKFC equation. About 12.6% of individuals were classified into a different CKD stage using the EKFC equation with 97.43% of these patients classified into a higher (more advanced) stage. There was a 25.9% increase in the number of patients identified as having CKD when calculated using the EKFC equation. Direct health costs also increased with the use of EKFC reporting.ConclusionUse of the EKFC equation will increase population prevalence of CKD and will result in a shift to higher stages of CKD. This has implications for monitoring and referral of patients within specialist services and has the potential to increase the need for multidisciplinary care.
Impact of claudin‐10 deficiency on amelogenesis: Lesson from a HELIX tooth
Authors: Obtel Nicolas , Le Cabec Adeline , Nguyen Thè Nghia , Giabicani Eloise , Van Malderen Stijn J. M. , Garrevoet Jan , Percot Aline , Paris Céline , Dean Christopher , Hadj‐Rabia Smail , Houillier Pascal , Breiderhoff Tilman , Bardet Claire , Coradin Thibaud , Ramirez Rozzi Fernando , Chaussain Catherine 
Published: July 2022

AbstractIn epithelia, claudin proteins are important components of the tight junctions as they determine the permeability and specificity to ions of the paracellular pathway. Mutations in CLDN10 cause the rare autosomal recessive HELIX syndrome (Hypohidrosis, Electrolyte imbalance, Lacrimal gland dysfunction, Ichthyosis, and Xerostomia), in which patients display severe enamel wear. Here, we assess whether this enamel wear is caused by an innate fragility directly related to claudin‐10 deficiency in addition to xerostomia. A third molar collected from a female HELIX patient was analyzed by a combination of microanatomical and physicochemical approaches (i.e., electron microscopy, elemental mapping, Raman microspectroscopy, and synchrotron‐based X‐ray fluorescence). The enamel morphology, formation time, organization, and microstructure appeared to be within the natural variability. However, we identified accentuated strontium variations within the HELIX enamel, with alternating enrichments and depletions following the direction of the periodical striae of Retzius. These markings were also present in dentin. These data suggest that the enamel wear associated with HELIX may not be related to a disruption of enamel microstructure but rather to xerostomia. However, the occurrence of events of strontium variations within dental tissues might indicate repeated episodes of worsening of the renal dysfunction that may require further investigations.
Red Wine Inspired Chromophores as Photodynamic Therapy Sensitizers†
Authors: Martins Lucas M. O. S. , Wang Xuhui , Silva Gustavo T. M. , Junqueira Helena C. , Fornaciari Bárbara , Lopes Lohanna F. , Silva Cassio P. , Zhou Peng , Cavalcante Victor F. , Baptista Mauricio S. , Quina Frank H. 
Published: July 2022

AbstractHydroxypyranoflavylium (HPF) cations are synthetic analogs possessing the same basic chromophore as the pyranoanthocyanins that form during the maturation of red wine. HPF cations absorb strongly in the visible spectral region, and most are fluorescent, triplet‐sensitize singlet oxygen formation in solution and are strong photooxidants, properties that are desirable in a sensitizer for photodynamic therapy (PDT). The results of this study demonstrate that several simple HPF dyes can indeed function as PDT sensitizers. Of the eight HPF cations investigated in this work, four were phototoxic to a human cervical adenocarcinoma cell line (HeLa) at the 1–10 μmol dm−3 level, while only one of the eight compounds showed noticeable cytotoxicity in the dark. Neither a Type I nor a Type II mechanism can adequately rationalize the differences in phototoxicity of the compounds. Colocalization experiments with the most phototoxic compound demonstrated the affinity of the dye for both the mitochondria and lysosomes of HeLa cells. The fact that relatively modest structural differences, e.g., the exchange of an electron‐donating substituent for an electron‐withdrawing substituent, can cause profound differences in the phototoxicity, together with the relatively facile synthesis of substituted HPF cations, makes them interesting candidates for further evaluation as PDT sensitizers.