bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perspektif Fishbein Model dalam Pengelolaan Pesan Persuasif Petani Agribisnis Pepaya Calina Melalui Media Sosial
Authors: Djaya Tika Ristia 
Published: April 2022

<p><em>Social media as a means to obtain information and knowledge and build relationships / relational that has its own allure because of low cost, can reach space and time. Thus the message will easily reach the communicant, so that feedback can be obtained immediately. In accordance with the communication function one of which is to persuade the communicant to support the message conveyed by the communicator. So that the communicant acts like a message delivered by the communicator. In this case the communicator is a calina papaya farmer and the communicant is a farmer in general in Magelang, Central Java. But it does not rule out the possibility that farmers in general can become communicators when the conversation occurs. This study aims to determine the farmers in Magelang, Central Java in getting information on calina papaya agribusiness from the perspective of the fishbein model. The research method used is a qualitative method with an explorative study approach. The results showed farmers in the area of Magelang had been inspired and obsessed with social media messages about the agribusiness of calina papaya as a planting option by considering yields. Thus it means that calina papaya farmers have managed the message as in the perspective of the fishbein model regarding the calina papaya agribusiness through various social media. This study concluded that: (1). Persuasive messages are managed by showing visual evidence, delivery methods, systematic / ways to develop content, so that the message is organized and can be trusted. (2). Publish strong arguments using language that is easy to understand and focuses more on experience. (3). Practice involvement. This involvement can be an educational practice as well as being able to interact among the farmers of calina papaya.</em></p>
Pengaruh Terpaan Iklan Marketplace, Akses Aplikasi, dan Minat Membeli Pada Mahasiswa
Authors: Norhabiba Fitri 
Published: April 2022

<p><em>As a new media, internet not only as production tools but also distributed message. Internet has a function like traditional media, internet as a storage message. Internet has many easier tools and become many application to be access many times. Consumer behavior has changed from traditional to online.</em></p><p><em>This research tried to examine aspect of elaboration likelihood model and advertising exposure and connected to consumer behavior on youth, especially students in the big city.</em></p><p><em>This research took place di University of 17 August Surabaya, located in the central city of Surabaya, and could be represent students. The population is students of Untag Surabaya 13849. The sampel is 160, based n slovin formula and used systematic random sampling. The type of the research is quantitative descriptive, the data used to generalize youth in the city.</em></p><p><em>The result show that there is a influence of marketplace’s advertising exposure, application access to buying interest toward student with linear regression. The influence of marketplace’s advertising exposure, application access to buying interest is 41,9%. R<sup>2</sup>=0,419,6 </em>β=0,408;p&lt;0,01.</p><p> </p><p><strong><em>Keywords: advertising exposure, buying interest</em></strong><strong>, <em>elaboration likelihood model</em></strong></p><div id="gtx-trans" style="position: absolute; left: 60px; top: 236px;"> </div>
Konstruksi Kuasa Presiden Jokowi dalam Pidato “Indonesia Darurat Corona”
Authors: Robin Patricia , Priscila Gabriela 
Published: April 2022

<p><em>Wabah Covid-19 merupakan titik balik kehidupan manusia. Segi kehidupan pribadi dan sosial berubah, waktu bekerja menjadi lama, dan pemilihan penggunaan media menjadi lebih terpola. Hal ini memunculkan kebijakan dan keputusan baru dari Pemerintah. Penelitian ini menggunakan Analisis Wacana Kritis Norman Fairclough untuk membongkar teks pidato Presiden Joko Widodo yang lekat dengan unsur kekuasaan dalam lingkup massif dan kooperatif. Adapun pembahasan ini melingkupi segi </em><em>wacana mikrostruktur membahas representasi, hubungan, dan identitas; analisis wacana mesostruktur, yang erat dengan produksi, konsumsi, dan reproduksi teks kekuasaan yang tidak seimbang; dilanjutkan dengan analisis wacana makrostruktur (sosiokultural) yang melihat dari aspek situasional, kelembagaan, dan sosial</em><em>. </em><em>Presiden Jokowi menjawab keresahan masyarakat mengenai penanganan wabah dan perekonomian, serta menunjukkan bahwa pemerintah telah melakukan usaha-usaha dan menyiapkan skenario-skenario untuk segala kemungkinan. Melalui pidato ini, Presiden Jokowi sekaligus merespon asumsi kepemimpinannya yang kurang tegas dan banyaknya ketidaksesuaian antara pusat dan daerah dengan menegaskan kebijakan mengenai PSBB</em><em>. Perhatian utama peneliti adalah pada pemilihan kata yang digunakan oleh Presiden Jokowi dalam penyampaian Pidato. Menjadi perhatian ketika sebuah keputusan yang ditetapkan oleh pemerintahan seakan menjadi pertunjukkan satu orang semata.</em></p><p><strong><em> </em></strong></p><p><strong><em>Keywords</em></strong><strong><em>: </em></strong><em>Norman Fairclough;<strong> </strong>Pidato Presiden Jokowi; Kekuasaan Foucault; PSBB<strong></strong></em></p>
Bersama Indonesia Power, Kembangkan Potensi Pariwisata Jawa Tengah untuk Pariwisata yang Berdikari Pasca Pandemi
Authors: Mardhiyani Nur Laili , Kinanthi Laksmi , Hidayat Satria Nur , Bertrand B.T Louis , Sofia Dina , Purbasiwi K Sekar , Shifananda V.P Jeva Shifananda V.P 
Published: April 2022

<p><em>Glagah Wangi Beach or Instanbul Demak is a beach in the coastal area of </em><em></em><em>Demak Regency which offers the beauty of Mangrove forest tourism. Glagah Wangi Beach is one of the tours that has become an icon of Demak Regency which is also included in the 10 nominations for new tourist destinations held by the Anugerah Pesona Indonesia (API) 2020. Glagah Wangi Beach itself is located in Tambak Bulusan Village, Dukuh Bongsari, Kec. Karang Tengah with the distance to the district center is approximately 20 km or 1 hour away by motorbike or car. This service aims to increase the potential of regional tourism to become the choice of tourist attractions in Central Java and Indonesia, increase the income of the surrounding community by developing tourism activities based on training and education on good tourism management in accordance with ISO standards, increasing brand awareness and brand reputation of PT. Indonesia Power; get PR Value in the form of news in the mass media (print, digital and electronic).</em></p><p><strong> </strong></p><p><strong><em>Keywords: </em></strong><em>Glagah Wangi Beach; Istanbul Demak; Tourism; Mangrove Forest</em></p>
Menjaga Stabilitas Perusahaan Bandeng Juwana Elrina melalui Perencanaan Program Community Relations Petani Tambak Wonoagung
Authors: Mardhiyani Nur Laili , Wulandari Arum Desti , Hanifa Millati , Ayunda Tsalsa Amilia , Krisnawan Elza Orvint 
Published: April 2022

<p class="Abstract"><em>The increasing number and development of companies and UMKM resulted in intense competition in the business world. To obtain support from various parties to maintain the survival of the company or UMKM, it is necessary to have Community Relations activities to maintain the stability of the activities of the company or UMKM. These activities are not limited to just looking for profit but also pay attention to the benefit of the surroundings or the target of Community Relations itself.</em></p><p class="Abstract"><em>This research is aimed at Milkfish Juwana Elrina with several proposed activity programs for the target, namely pond farmers in Wonoagung Village, Demak Regency with several programs such as training, empowerment, and the provision of other facilities.</em></p><p class="Abstract"><em>The purpose of this research is to create a relationship with the target audience, provide a new product for Milkfish Juwana Elrina and improve the welfare of the people of Wonoagung Village, Demak Regency.</em></p><p class="Abstract"><em>This study uses a descriptive qualitative research method. Descriptive research is to describes the quality of a symptom to make the reader know what is happening in the related research.</em></p><p> </p>
Review of: Michael J. B. Allen, Studies in the Platonism of Marsilio Ficino and Giovanni Pico, Routledge, London–New York 2017 (Variorum Collected Studies Series,1063). XIII + 348 pp., ISBN: 9781472448385.
Authors: Monfasani John 
Published: April 2022

Review of:
Michael J. B. Allen, Studies in the Platonism of Marsilio Ficino and Giovanni Pico, Routledge, London–New York 2017 (Variorum Collected Studies Series,1063). XIII + 348 pp., ISBN: 9781472448385.
Review of: Cecilia Muratori, Renaissance Vegetarianism: The Philosophical Afterlives of Porphyry’s ‘On Abstinence’, Legenda, Cambridge 2020 (Italian Perspectives, 46), 276 pp., ISBN 9781781883389.
Authors: Durán Mañas Monica 
Published: April 2022

Review of:
Cecilia Muratori, Renaissance Vegetarianism: The Philosophical Afterlives of Porphyry’s ‘On Abstinence’, Legenda, Cambridge 2020 (Italian Perspectives, 46), 276 pp., ISBN 9781781883389.
Review of: Florian Hamann, Das Renaissanceabenteuer, Muslime zu bekehren. Ein philosophischer Feldzug, Wissenschaftliche Buchgesellschaft, Darmstadt 2021, 283 pp., ISBN: 9783534404599.
Authors: Imbach Ruedi 
Published: April 2022

Review of:
Florian Hamann, Das Renaissanceabenteuer, Muslime zu bekehren. Ein philosophischer Feldzug, Wissenschaftliche Buchgesellschaft, Darmstadt 2021, 283 pp., ISBN: 9783534404599.
Review of: Massimiliano Traversino Di Cristo (ed.), Giordano Bruno: Law, Philosophy, and Theology in the Early Modern Era, Classiques Garnier, Paris 2021 (Works from the Centre for Further Study of the Renaissance, 7), 478 pp., ISBN: 9782406104469.
Authors: Brotto Luisa 
Published: April 2022

Review of:
Massimiliano Traversino Di Cristo (ed.), Giordano Bruno: Law, Philosophy, and Theology in the Early Modern Era, Classiques Garnier, Paris 2021 (Works from the Centre for Further Study of the Renaissance, 7), 478 pp., ISBN: 9782406104469.
Review of: Laura Stagno, Borja Franco Llopis (eds.), Lepanto and Beyond. Images of Religious Alterity from Genoa and the Christian Mediterranean, Leuven University Press, Leuven 2021, 324 pp., ISBN: 9462702640.
Authors: Zardin Danilo 
Published: April 2022

Review of:
Review of: Laura Stagno, Borja Franco Llopis (eds.), Lepanto and Beyond. Images of Religious Alterity from Genoa and the Christian Mediterranean, Leuven University Press, Leuven 2021, 324 pp., ISBN: 9462702640.
Review of: Bente Maegaard, Riccardo Pozzo, Alberto Melloni, Matthew Woollard (eds.), Stay Tuned to the Future: Impact of the Research Infrastructures for Social Sciences and Humanities, Leo S. Olschki, Firenze 2019, XXXVI + 190 pp., ISBN: 9788822266439.
Authors: Fantoli Margherita 
Published: April 2022

Review of:
Bente Maegaard, Riccardo Pozzo, Alberto Melloni, Matthew Woollard (eds.), Stay Tuned to the Future: Impact of the Research Infrastructures for Social Sciences and Humanities, Leo S. Olschki, Firenze 2019 (Lessico intellettuale europeo, 128), XXXVI + 190 pp., ISBN: 9788822266439.
Review of: Valery Rees, Anna Corrias, Francesca M. Crasta, Laura Follesa, Guido Giglioni (eds.), Platonism, Ficino to Foucault, Leiden–Boston, Brill 2021 (Brill’s Studies in Intellectual History, 320), 357 pp., ISBN: 9789004358935.
Authors: Steiris Georgios 
Published: April 2022

Review of:
Valery Rees, Anna Corrias, Francesca M. Crasta, Laura Follesa, Guido Giglioni (eds.), Platonism, Ficino to Foucault, Leiden–Boston, Brill 2021 (Brill’s Studies in Intellectual History, 320), 357 pp., ISBN: 9789004358935.
Exploring Robust Architectures for Deep Artificial Neural Networks
Authors: Waqas Asim , Rasool Ghulam , Farooq Hamza , Bouaynaya Nidhal 
Published: April 2022

Abstract
The architectures of deep artificial neural networks (DANNs) are routinelystudied to improve their predictive performance. However, the relationshipbetween the architecture of a DANN and its robustness to noiseand adversarial attacks is less explored. We investigate how the robustnessof DANNs relates to their underlying graph architectures or structures.This study: (1) starts by exploring the design space of architecturesof DANNs using graph-theoretic robustness measures; (2) transforms thegraphs to DANN architectures to train/validate/test on various imageclassification tasks; (3) explores the relationship between the robustnessof trained DANNs against noise and adversarial attacks and the robustnessof their underlying architectures estimated via graph-theoreticmeasures. We show that the topological entropy and Olivier-Ricci curvatureof the underlying graphs can quantify the robustness performanceof DANNs. The said relationship is stronger for complex tasks and largeDANNs. Our work will allow autoML and neural architecture searchcommunity to explore design spaces of robust and accurate DANNs.
Increased expression of syncytin-1 in skeletal muscle of humans with increased body mass index
Authors: Ravichandran Jayachandran , Roust Lori R , Katsanos Christos 
Published: April 2022

Abstract
Obesity negatively impacts skeletal muscle protein metabolism, and also impairs skeletal muscle maintenance and regeneration. We analyzed muscle biopsy samples from humans with increased body mass index (BMI) (i.e. > 30 kg/m2) and controls (i.e., BMI < 25 kg/m2) for expression of syncytin-1, a fusogenic protein regulating skeletal muscle regeneration. When compared to controls, humans with increased BMI and concomitant reduction in muscle protein synthesis had higher expression of syncytin-1 in skeletal muscle (P < 0.05). Across human subjects, muscle protein synthesis correlated inversely (r = -0.51; P = 0.03) with syncytin-1 expression in muscle. Using a C2C12 cell line we found that expression of syncytin-A (i.e, corresponding protein in murine tissue) is increased by insulin, and that this response is impaired in the presence of fatty acids, whose metabolism is altered within the metabolic environment induced by increased BMI. In C2C12 cells, the response of the protein 4E-BP1, which signals increase in protein synthesis in muscle, resembled that of syncytin-A. These findings provide novel insights into the expression of syncytin-1 in skeletal muscle of humans with increased BMI, as well as its basic regulation by insulin and fatty acids in muscle. The findings signify the need for further research into the regulation of syncytin-1 in skeletal muscle of humans with increased BMI, as well as its biological implications for altering muscle protein metabolism and regeneration.
Beneficial Effects of Carvacrol on In Vitro Models of Metabolically-Associated Liver Steatosis and Endothelial Dysfunction: A Role for Fatty Acids in Interfering with Carvacrol Binding to Serum Albumin
Authors: Khalil Mohamad , Serale Nadia , Diab Farah , Baldini Francesca , Portincasa Piero , Lupidi Giulio , Vergani Laura 
Published: April 2022

Background:
Carvacrol, a plant phenolic monoterpene, is largely employed as
food additive and phytochemical.

Objective:
We aimed to assess the lipid lowering and protective effects of carvacrol in
vitro using cellular models of hepatic steatosis and endothelial dysfunction. We also investigated
if and how the binding of carvacrol to albumin, the physiological transporter
for small compounds in the blood, might be altered by the presence of high levels of fatty
acids (FAs).

Methods:
Hepatic FaO cells treated with exogenous FAs mimic hepatosteatosis; endothelial
HECV cells exposed to hydrogen peroxide are a model of endothelial dysfunction. In
these models, we measured spectrophotometrically lipid accumulation and release,
lipoperoxidation, free radical production, and nitric oxide release before and after treatment
with carvacrol. The carvacrol binding to albumin in the presence or absence of high
levels of FAs was assessed by absorption and emission spectroscopies.

Results:
Carvacrol counteracted lipid accumulation and oxidative stress in hepatocytes
and protected endothelial cells from oxidative stress and dysfunction. Moreover, high levels
of FAs reduced the binding of carvacrol to albumin.

Conclusion:
The results suggest the good potential of carvacrol in ameliorating dysfunction
of hepatic and endothelial cells in vitro. High levels of circulating FAs might compete
with carvacrol for binding to albumin thus influencing its transport and bio-distribution.
Selective Delivery of Clinically Approved Tubulin Binding Agents through Covalent Conjugation to an Active Targeting Moiety
Authors: Collyer Samuel E. , Stack Gary D. , Walsh John J. 
Published: April 2022

Abstract:
The efficacy and tolerability of tubulin binding agents are hampered by their
low specificity for cancer cells like most clinically used anticancer agents. To improve
specificity, tubulin binding agents have been covalently conjugated to agents that target
cancer cells to give actively targeted drug conjugates. These conjugates are designed to
increase uptake of the drug by cancer cells while having limited uptake by normal cells,
thereby improving efficacy and tolerability. Approaches used include an attachment to
small molecules, polysaccharides, peptides, proteins, and antibodies that exploit the overexpression
of receptors for these substances. Antibody targeted strategies have been the
most successful to date, with six such examples having gained clinical approval. Many
other conjugate types, especially those targeting the folate receptor, have shown promising
efficacy and toxicity profiles in pre-clinical models and in early-stage clinical
studies. Presented herein is a discussion of the success or otherwise of the recent strategies
used to form these actively targeted conjugates.
Insights into Interactions of Human Cytochrome P450 17A1: A Review
Authors: Singh Himanshu , Kumar Rajnish , Mazumder Avijit , Salahuddin  , Mazumder Rupa , Abdullah Mohd. Mustaqeem 
Published: April 2022

Abstract:
Cytochrome P450s are a widespread and vast superfamily of hemeprotein monooxygenases that metabolize
physiologically essential chemicals necessary for most species' survival, ranging from protists to plants to humans.
They catalyze the synthesis of steroid hormones, cholesterol, bile acids, and arachidonate metabolites and the
degradation of endogenous compounds, such as steroids, fatty acids, and other catabolizing compounds as an energy
source and detoxifying xenobiotics, such as drugs, procarcinogens, and carcinogens. The human CYP17A1 is one of
the cytochrome P450 genes located at the 10q chromosome. The gene expression occurs in the adrenals and gonads,
with minor amounts in the brain, placenta, and heart. This P450c17 cytochrome gene is a critical steroidogenesis
regulator which performs two distinct activities: 17 alpha-hydroxylase activity (converting pregnenolone to 17-
hydroxypregnenolone and progesterone to 17-hydroxyprogesterone; these precursors are further processed to provide
glucocorticoids and sex hormones) and 17, 20-lyase activity (which converts 17-hydroxypregnenolone to DHEA).
Dozens of mutations within CYP17A1 are found to cause 17-alpha-hydroxylase and 17, 20-lyase deficiency. This
condition affects the function of certain hormone-producing glands, resulting in high blood pressure levels (hypertension),
abnormal sexual development, and other deficiency diseases. This review highlights the changes in CYP17A1
associated with gene-gene interaction, drug-gene interaction, chemical-gene interaction, and its biochemical reactions;
they have some insights to correlate with the fascinating functional characteristics of this human steroidogenic
gene. The findings of our theoretical results will be helpful to further the design of specific inhibitors of CYP17A1.
Draft Genome Sequence of the Earthworm Eudrilus eugeniae
Authors: Sivasubramaniam Sudhakar , Arumugaperumal Arun , Sudalaimani Dinesh Kumar , Arumugaswami Vaithilingaraja 
Published: April 2022

Background:
Earthworms are annelids. They play a major role in agriculture and soil fertility. Vermicompost is the best organic manure for plant crops. Eudrilus eugeniae is an earthworm well
suited for efficient vermicompost production. The worm is also used to study the cell and molecular
biology of regeneration, molecular toxicology, developmental biology, etc., because of its abilities like
high growth rate, rapid reproduction, tolerability toward wide temperature range, and less cost of
maintenance.

Objective:
The whole genome has been revealed only for Eisenia andrei and Eisenia fetida.

Methods:
In the present work, we sequenced the genome of E. eugeniae using the Illumina platform
and generated 160,684,383 paired-end reads

Results:
The reads were assembled into a draft genome of size 488 Mb with 743,870 contigs and successfully annotated 24,599 genes. Further, 208 stem cell-specific genes and 3,432 non-coding genes
were identified.
Vitamin D and its Possible Relationship to Neuroprotection in COVID-19:
Evidence in the Literature
Authors: Quintero-Fabián Saray , Bandala Cindy , Pichardo-Macías Luz Adriana , Contreras-García Itzel Jatziri , Gómez-Manzo Saúl , Hernández-Ochoa Beatriz , Martínez-Orozco José Arturo , Ignacio- Mejía Iván , Cárdenas-Rodríguez Noemí 
Published: April 2022

Abstract:
Vitamin D is a hormone involved in the regulation of important biological processes such
as signal transduction, immune response, metabolic regulation and also in the nervous and vascular
systems. To date, coronavirus disease 2019 (COVID-19) infection does not have a specific treatment.
However, various drugs have been proposed, including those that attenuate the intense inflammatory
response, and recently, the use of vitamin D, in clinical trials, as part of the treatment of
COVID-19 has provided promising results. It has been observed in some clinical studies that the use
of cholecalciferol (vitamin D3) and its two metabolites the circulating form, calcidiol or calcifediol
(25-hydroxycalciferol, 25-(OH)-D), and the active form, calcitriol (1,25-(OH)2-D), in different doses,
improve the clinical manifestations, prognosis, and survival of patients infected with COVID-19
probably because of its anti-inflammatory, antiviral and lung-protective action. In relation to the
central nervous system (CNS) it has been shown, in clinical studies, that vitamin D is beneficial in
some neurological and psychiatric conditions because of its anti-inflammatory and antioxidant
properties, modulation of neurotransmitters actions, and regulation of calcium homeostasis between
other mechanisms. It has been shown that COVID-19 infection induces CNS complications such as
headache, anosmia, ageusia, neuropathy, encephalitis, stroke, thrombosis, cerebral hemorrhages, cytotoxic
lesions, and psychiatric conditions and it has been proposed that the use of dietary supplements,
as vitamin and minerals, can be adjuvants in this disease. In this review, the evidence of the
possible role of vitamin D, and its metabolites, as a protector against the neurological manifestations
of COVID-19 was summarized.