bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the Potential Relationship Between Global Greenness and DALY Loss Due to Depressive Disorders
Authors: Asri Aji Kusumaning , Tsai Hui-Ju , Pan Wen-Chi , Guo Yue Leon , Yu Chia-Pin , Wu Chi-Shin , Su Huey-Jen , Lung Shih-Chun Candice , Wu Chih-Da , Spengler John D. 
Published: June 2022

ObjectivePrior studies have shown that greenness can reduce the burden of depressive disorders. However, most were focused on local-scale analyses while limited evaluated globally. We aimed to investigate the association between greenness and the burden of depressive disorders using data from 183 countries worldwide.MethodsWe used the normalized difference vegetation index (NDVI) to estimate greenness. Country-level disability-adjusted life year (DALY) loss due to depressive disorders was used to represent depressive disorder burdens. A generalized linear mixed model was applied to assess the relationship between greenness and depressive disorders after controlling for covariates. Stratified analyses were conducted to determine the effects of greenness across several socio-demographic levels.ResultsThe findings showed a significant negative association between greenness and the health burden of depressive disorders with a coefficient of −0.196 (95% CI: −0.356, −0.035) in the DALY changes per interquartile unit increment of NDVI. The stratified analyses suggested beneficial effects of greenness on depressive disorders across sex, various age groups especially for those aged &lt;49 years, with low-income and/or those living in highly urbanized countries.ConclusionsOur study noted that greenness exposure was significant negative association with the burden of depressive disorders. The findings should be viewed as recommendations for relevant authorities in supporting environmental greenness enhancement to reduce the mental burdens.
Novel Functional eQTL-SNPs Associated With Susceptibility to Mycoplasma pneumoniae Pneumonia in Children
Authors: Dong Yang , Gao Yanmin , Luo Cheng , Wu Nengshun , Cheng Zhounan , Qiu Anni , Zhou Yan , Zhang Wendi , Chu Minjie , Chang Qing 
Published: June 2022

BackgroundThe functional causal single-nucleotide polymorphisms (SNPs) associated with susceptibility to Mycoplasma pneumoniae Pneumonia (MPP) have scarcely been identified. In this study, we aimed to analyze the association between the functional expression quantitative trait locus (eQTL)-SNPs and the risk of MPP.MethodsFirst, we identified reported genes associated with MPP from the human disease database, MalaCards. After investigating multiple databases, we systematically selected seven functional eQTL-SNPs (rs2070874, rs360720, rs8032531, rs4316, rs4353, rs7258241, and rs2250656). Finally, the selected eQTL-SNPs were genotyped using the TaqMan genotyping technology, and compared between 100 children with MPP and 178 healthy controls.ResultsWe found that three eQTL-SNPs (rs8032531 in CD276 and rs4316 and rs4353 in ACE) were significantly associated with susceptibility to MPP. Joint analysis of the three eQTL-SNPs revealed that the risk of MPP increased with an increase in the number of risk alleles present. Plasma protein expression levels of CD276 and ACE were distinctively higher in children with MPP than in healthy children (CD276: P &lt; 0.001; ACE: P = 0.001).ConclusionFunctional eQTL-SNPs in CD276 and ACE may affect the susceptibility to MPP. The risk of developing MPP is higher in patients harboring a greater number of unfavorable alleles of the aforementioned SNPs.
Satisfaction as a Mediator and Its Interaction With Adherence to Labor Analgesia Protocols: A Cross-Sectional Survey of Chinese Medical Personnel
Authors: Lang Dong , Long Chengxu , Lin Shuna , Xie Yinghua , Chen Fangfei , Zhao Rui , Liu Chunping , Tang Shangfeng 
Published: June 2022

BackgroundAlthough the Chinese promotion of labor analgesia began in 2018 to improve maternal health, high-quality medical care is difficult to provide to pregnant women when medical staff cannot implement standard labor analgesia procedures. This study aims to examine medical personnel's adherence to labor analgesia protocols and to explore the relationships among adherence, satisfaction, and other factors.MethodsThe data were from a national cross-sectional dataset (N = 13,944) of the 2020 Chinese Labor Analgesia Pilot Evaluation Project. Mediating and moderating effects analyses were used to examine the role of satisfaction as a mediator between support measures and adherence.ResultsThere were differences in adherence between different types of medical personnel. Support measures and satisfaction had a positive association with adherence to labor analgesia protocols. Satisfaction had a significant mediating and moderating effect on the relationship between support measures and adherence to labor analgesia standards. Moderating effects of professional titles and attitudes were also observed.ConclusionPrimary health care policies worth considering include comprehensive incentives for medical institutions to improve the use of labor analgesia by medical personnel. It is also worth considering providing more training opportunities for the staff in anesthesiology departments.
Prediction of Lumbar Drainage-Related Meningitis Based on Supervised Machine Learning Algorithms
Authors: Wang Peng , Cheng Shuwen , Li Yaxin , Liu Li , Liu Jia , Zhao Qiang , Luo Shuang 
Published: June 2022

BackgroundLumbar drainage is widely used in the clinic; however, forecasting lumbar drainage-related meningitis (LDRM) is limited. We aimed to establish prediction models using supervised machine learning (ML) algorithms.MethodsWe utilized a cohort of 273 eligible lumbar drainage cases. Data were preprocessed and split into training and testing sets. Optimal hyper-parameters were archived by 10-fold cross-validation and grid search. The support vector machine (SVM), random forest (RF), and artificial neural network (ANN) were adopted for model training. The area under the operating characteristic curve (AUROC) and precision-recall curve (AUPRC), true positive ratio (TPR), true negative ratio (TNR), specificity, sensitivity, accuracy, and kappa coefficient were used for model evaluation. All trained models were internally validated. The importance of features was also analyzed.ResultsIn the training set, all the models had AUROC exceeding 0.8. SVM and the RF models had an AUPRC of more than 0.6, but the ANN model had an unexpectedly low AUPRC (0.380). The RF and ANN models revealed similar TPR, whereas the ANN model had a higher TNR and demonstrated better specificity, sensitivity, accuracy, and kappa efficiency. In the testing set, most performance indicators of established models decreased. However, the RF and AVM models maintained adequate AUROC (0.828 vs. 0.719) and AUPRC (0.413 vs. 0.520), and the RF model also had better TPR, specificity, sensitivity, accuracy, and kappa efficiency. Site leakage showed the most considerable mean decrease in accuracy.ConclusionsThe RF and SVM models could predict LDRM, in which the RF model owned the best performance, and site leakage was the most meaningful predictor.
Robotic Versus Laparoscopic Gastrectomy for Gastric Cancer: A Mega Meta-Analysis
Authors: Baral Shantanu , Arawker Mubeen Hussein , Sun Qiannan , Jiang Mingrui , Wang Liuhua , Wang Yong , Ali Muhammad , Wang Daorong 
Published: June 2022

BackgroundLaparoscopic gastrectomy and robotic gastrectomy are the most widely adopted treatment of choice for gastric cancer. To systematically assess the safety and effectiveness of robotic gastrectomy for gastric cancer, we carried out a systematic review and meta-analysis on short-term and long-term outcomes of robotic gastrectomy.MethodsIn order to find relevant studies on the efficacy and safety of robotic gastrectomy (RG) and laparoscopic gastrectomy (LG) in the treatment of gastric cancer, numerous medical databases including PubMed, Medline, Cochrane Library, Embase, Google Scholar, and China Journal Full-text Database (CNKI) were consulted, and Chinese and English studies on the efficacy and safety of RG and LG in the treatment of gastric cancer published from 2012 to 2022 were screened according to inclusion and exclusion criteria, and a meta-analysis was conducted using RevMan 5.4 software.ResultsThe meta-analysis inlcuded 48 literatures, with 20,151 gastric cancer patients, including 6,175 in the RG group and 13,976 in the LG group, respectively. Results of our meta-analysis showed that RG group had prololonged operative time (WMD = 35.72, 95% CI = 28.59–42.86, P &lt; 0.05) (RG: mean ± SD = 258.69 min ± 32.98; LG: mean ± SD = 221.85 min ± 31.18), reduced blood loss (WMD = −21.93, 95% CI = −28.94 to −14.91, P &lt; 0.05) (RG: mean ± SD = 105.22 ml ± 62.79; LG: mean ± SD = 127.34 ml ± 79.62), higher number of harvested lymph nodes (WMD = 2.81, 95% CI = 1.99–3.63, P &lt; 0.05) (RG: mean ± SD = 35.88 ± 4.14; LG: mean ± SD = 32.73 ± 4.67), time to first postoperative food intake shortened (WMD = −0.20, 95% CI = −0.29 to −0.10, P &lt; 0.05) (RG: mean ± SD = 4.5 d ± 1.94; LG: mean ± SD = 4.7 d ± 1.54), and lower length of postoperative hospital stay (WMD = −0.54, 95% CI = −0.83 to −0.24, P &lt; 0.05) (RG: mean ± SD = 8.91 d ± 6.13; LG: mean ± SD = 9.61 d ± 7.74) in comparison to the LG group. While the other variables, for example, time to first postoperative flatus, postoperative complications, proximal and distal mar gin, R0 resection rate, mortality rate, conversion rate, and 3-year overall survival rate were all found to be statistically similar at P &gt; 0.05.ConclusionsIn the treatment of gastric cancer, robotic gastrectomy is a safe and effective procedure that has both short- and long-term effects. To properly evaluate the advantages of robotic surgery in gastric cancer, more randomised controlled studies with rigorous research methodologies are needed.
Identification and Verification of SLC27A1, PTBP1 and EIF5A With Significantly Altered Expression in Aggressive Pituitary Adenomas
Authors: Cheng Jianhua , Sun Ruya , Nie Ding , Li Bin , Gui Song Bai , Li Chu Zhong , Zhang Ya Zhuo , Zhao Peng 
Published: June 2022

BackgroundAggressive pituitary adenoma encircling the internal carotid artery has a poor clinical prognosis because of a high surgical risk and a high recurrence rate. This seriously affects patients’ quality of life and yet there is no effective medical treatment. The European Diagnostic Guidelines have recommended the use of temozolomide (TMZ) for these aggressive pituitary adenomas, but the treatment remission rate has been less than 50%.MethodsIn this study, transcriptome sequencing of pituitary tumour tissues and TMZ-treated pituitary tumour cell lines were employed to explore the significance gene expressions affecting the efficacy of TMZ treatment for pituitary tumours. To clarify the roles of these gene expressions, six adult patients with pituitary adenomas treated in Tiantan Hospital from 2015 to 2020 and a pituitary adenoma cell line (Att20 sensitive to TMZ treatment) were analyzed by mRNA transcriptome sequencing. The differentially expressed genes were assayed by analyzing the sequencing results, and the expression level of these genes was further verified by immunohistochemistry. In addition, Ki67, VEGF, and p53 of the tumour tissues were also verified by immunohistochemistry.ResultsIn tumour tissues, mRNA sequencing showed that PTBP1 and EIF5A were significantly overexpressed in primary pituitary adenomas and SLC27A1 was significantly overexpressed in aggressive pituitary adenomas. Also in the pituitary adenoma cell line (AtT20), SLC27A1 expression levels were suppressed by TMZ treatment. Subsequent immunohistochemistry confirmed the sequencing results.ConclusionHigh expression of SLC27A1 and low expression of EIF5A and PTBP1 may be potential indicators to predict the progression of aggressive pituitary adenomas, and patients with high SLC27A1 subtype may be sensitive to TMZ in clinical treatments.
PREVENTION AND TREATMENT OF POSTPARTUM HEMORRHAGE: A LITERATURE REVIEW
Authors: Bitbit Yohana Rita , Ahmad Mardiana , Sunarno Isharyah 
Published: June 2022

Background: The main cause of morbidity and maternal mortality is hemorrhage postpartum, with an increasing incidence around the world. Various risk factors for postpartum bleeding are expected to be an effective treatment by health professionals and have a role as advocates, collaborators, educators, service providers, and as researchers must have the latest knowledge in providing optimal and comprehensive care.
Objectives: This study aimed to find out the prevention and treatment of hemorrhage postpartum.
Design: This study design is a systematic review to search and review articles from database and the descriptive theory.
Data Sources: Search scientific articles using the Mendeley application by entering the keywords "Postpartum, Hemorrhage, Prevention, and Treatment" with publication year 2019-2021, English, full text, and open access.
Review Methods: The literature review method uses a narrative review to discuss postpartum hemorrhage, its prevention, and treatment. The inclusion criteria are the year of publication 2019-2021, international publications, articles in English, original articles, full text, and open access. Data were collected and a journal summary was made which included the name of the researcher, year of publication of the journal, research title, method, and a summary of the results or findings.
Results: From 9 journals that meet the conclusion that active management of the third stage, administration of uterotonics and bimanual compression, is the initial treatment for the prevention and treatment of postpartum hemorrhage.
Conclusion: In the prevention of risk factors for postpartum hemorrhage, it is recommended to carry out good active management of the third stage, use of uterotonic drugs according to the recommended dose, early initiation of breastfeeding, and increase the knowledge and skills of health workers.
THE KIND OF MINDFULNESS INTERVENTION FOR ANXIETY IN UNDERGRADUATE NURSING STUDENTS: A LITERATURE REVIEW
Authors: Prasetya Rikhan Luhur , Dwidiyanti Meidiana , Dewi Nur Setiawati 
Published: June 2022

Background: Undergraduate nursing students have experience high levels of anxiety caused by academic, clinical practice and final assignments. This anxiety results in a decrease in students’ intellectual abilities and the risk of experiencing academic failures. Mindfulness is an effective intervention for reducing anxiety.
Objectives: This scoping review aims to determine the kind of mindfulness interventions to reduce anxiety in undergraduate nursing students.
Design: This study used a scoping review through a review of articles the kind of mindfulness interventions to reduce anxiety in undergraduate nursing students.
Data Sources: Search for articles accessed through a database, including: Science Direct, Scopus, Semantic Scholar, ProQuest and SpringerLink with a range of search years 2017 to 2021. The search for articles uses the boolean method of the “OR/AND” operator. The keywords used in the article search were “Mindfulness” AND “Anxiety” AND “Undergraduate”, AND “Nursing” OR “Mindfulness Based Cognitive Therapy” OR “Mindfulness Based Stress Reduction” OR “Mindfulness Based”.
Review Methods: This article uses Arksey and O'Melley's model in the analysis. Identification and analysis using Preferred Reporting Items for Systematic Reviews and Meta-Analysis for Scooping Review (PRISMA-SR).
Results: The result of this literature review show contains 5 quantitative articles. This article summarizes the kind of mindfulness interventions used to reduce anxiety in nursing students are mindfulness based cognitive therapy, mindfulness meditation, virtual community mindfulness, mindfulness through smartphones, and spiritual mindfulness. Mindfulness intervention provides serenity, focus on the situation with full awareness, acceptance, improvement in physical health, psychological, empathy, and well-being. The mindfulness was carried out 6 times in a series of interventions. The stages of mindfulness interventions vary widely, but the point is to focus attention and acceptance with awareness.
Conclusion: The kind of mindfulness interventions used to reduce anxiety in nursing students including: mindfulness based cognitive therapy, mindfulness meditation, virtual community mindfulness, mindfulness spiritual Islam and acceptance, and spiritual mindfulness.
The ways social networks shape reflection on early significant clinical experiences in medical school
Authors: Stasiuk Samantha , Hubinette Maria , Nimmon Laura 
Published: June 2022

Background: Medical curricula are increasingly providing opportunities to guide reflection for medical students. However, educational approaches are often limited to formalized classroom initiatives where reflection is prescriptive and measurable. There is paucity of literature that explores the personal ways students may experience authentic reflection outside of curricular time. The purpose of this study was to understand how social networks might shape dimensions of reflection.
Methods: This study employed a qualitative social network analysis approach with a core sample of seven first year undergraduate medical students who described their relationships with 61 individuals in their networks. Data consisted of participant generated sociograms and individual semi-structured interviews.
Results: Many learners struggled to find significant ways to involve their social networks outside of medicine in their new educational experiences. It appeared that some medical students began in-grouping, becoming more socially exclusive. Interestingly, participants emphasized how curricular opportunities such as reflective portfolio sessions were useful for capturing a diversity of perspectives.
Conclusions: Our study is one of the first to characterize the social networks inside and outside of medical school that students utilize to discuss and reflect on early significant clinical experiences. Recent commentary in the literature has suggested reflection is diverse and personal in nature and our study offers empirical evidence to demonstrate this. Our insights emphasize the importance of moving from an instrumental approach to an authentic socially situated approach if we wish to cultivate reflective lifelong learning.
Dirāsah Tahlīliyah Linushush Kitāb Ta’lim Allughah Al’arabiyah Lilshafi Al awal Al tsānawī Liwizārah Alsyu`ūwn Aldīniyah Al Indūnīsiyah ām 2020 (Alfashl Al awal Hatā Alfashl Altsālits Namudzajā)
Authors: Fauzi Muhammad Ikhwanul , Ismail Hadil , Anwar Saeful 
Published: June 2022

Abstract
This study aims to learn how to analyze the texts in the Arabic language education book for the first grade secondary of the Indonesian Ministry of Religious Affairs in 2020 (chapterone to chapter three as a model). This study follows the analytical description approach, tracking texts in the Arabic language education book for the first grade of secondary school of the Indonesian Ministry of Religious Affairs in 2020 (chapterone to chapter three as amodel) and collecting, classifying, presenting and concluding. This study proved that the texts in thisbook are generally appropriate and appropriate for students in the first grade ofsecondary school taking into account its objectives, content, method, and methods of presentation of the lesson with some observations that need to be modified in this book.
Abstrak
Penelitian ini bertujuan untuk mempelajari cara menganalisis teks-teks dalam buku pendidikan bahasa Arab untuk kelas satu sekunder Kementerian Agama Indonesia tahun 2020 (bab satu hingga bab tiga sebagai model). Penelitian ini mengikuti pendekatan deskripsi analitis, melacak teks dalam buku pendidikan bahasa Arab untuk kelas satu sekolah menengah Kementerian Agama Indonesia pada tahun 2020 (bab satu hingga bab tiga sebagaimodel) dan mengumpulkan, mengklasifikasikan, menyajikan dan menyimpulkan. Penelitian ini membuktikan bahwa teks-teks dalam buku ini umumnya sesuai untuk siswa di kelas satu sekolah menengah dengan mempertimbangkan tujuan, konten, metode, dan metode penyajian pelajaran dengan beberapa pengamatan yang perlu dimodifikasi dalam buku ini.
ملخص البحث
تهدف هذه الدراسة إلى التعرف على كيفية تحليل النصوص في كتاب تعليم اللغة العربية للصف الأول الثانوي لوزارة الشؤون الدينية الإندونيسية عام 2020 (الفصل الأول حتى الفصل الثالث نموذجا). وذلك بتحليل المعايير المناسبة من مادة النصوص في هذا الكتاب وبيان تنظيم المواد التراكيب والمفردات والتعبيرات، بحيث إنها تعين المعلمين والمتعلمين على فهم مادة النصوص في هذا الكتاب و اكتشاف نظام مواد التراكيب والمفردات والتعبيرات إجمالا. إن هذه الدراسة تسلك منهج الوصف التحليلي, وذلك بتتبع النصوص في كتاب تعليم اللغة العربية للصف الأول الثانوي لوزارة الشؤون الدينية الإندونيسية عام 2020 (الفصل الأول حتى الفصل الثالث نموذجا) وجمعه، وتصنيفه، وعرضه والاستنتاج .أثبتت هذه الدراسة أن النصوص في هذا الكتاب ملائم ومناسب على وجه العموم للطلاب في الصف الأول الثانوي بمراعاة أهدافه، ومحتواه، وطريقته، وأساليب عرض الدرس مع بعض الملاحظات التي تحتاج إلى تعديلها في هذا الكتاب
Growth Profile in Pediatric Patients with Diabetes Mellitus at Dr. M. Djamil General Hospital, Padang
Authors: Sephberlian Michael Mettafortuna , Eka Agustia Rini  
Published: June 2022

Background: Diabetes mellitus (DM) is a glucose metabolism disorder characterized by chronic hyperglycemia that often occurs and is a major health problem. During puberty, increased Growth Hormone (GH) secretion results in increased insulin resistance. This study aimed to describe the growth profile of pediatric patients with diabetes mellitus at Dr. M. Djamil General Hospital.
Methods: A descriptive retrospective study with conducted by collecting data on body height, HbA1C level, and status of puberty from medical records at the pediatric ward of Dr. M. Djamil General Hospital from January 2019 - December 2020.
Results: The sample was 67 (63 T1DM, 2 T2DM, and 2 double DM). Ten of them with short stature (8 with poor metabolic control).
Conclusion: Children with DM may experience growth disturbance.
PENINGKATAN ADAPTASI KEBIASAAN BARU COVID 19 BERSAMA DRIVER PARIWISATA
Authors: Jayanti Desak made ari dwi , Nopitawati Ni Made Nopitawati , Lestari Ni Kadek Yuni , Thrisnadewi Ni Luh Putu , Sudarma I Nyoman 
Published: June 2022

Kesehatan merupakan hal yang sangat penting, menjaga kesehatan perlu dilakukan baik secara fisik maupun jiwa. Pandemic Covid 19 menimbulkan permasalahn baik dari segi kesehatan fisik dan juga kesehatan jiwa. Driver Pariwista merupakan salah satu sektor terdampak Covid 19. Tujuan pengabdian masyarakat ini adalah meningkatkan dapatasi kebiasan baru Covid 19 untuk menjaga kesehatan fisik dan jiwa. Metode kegiatan dilakukan dengan memberikan pelatihan Adaptasi Kebiasan Baru Covid 19 secara langsung selama tiga hari dan melakukan pre-test dan post-test. Kegiatan pengabdian ini dikuti oleh Driver Pariwisata United Bali Driver yang berada di Wilayah Peguyangan Kangin. Hasil kegiatan menunjukan bahwa 100% peserta pengabdian masyarakat dapat memahami bagaimana upaya dalam meningkatkan kesehatan dengan melakukan Adaptasi Kebiasan Baru Covid 19 yaitu meningkatkan imunitas fisik, meningkatkan ketahanan kesehatan jiwa, mencegah penularan Covid 19, mencegah masalah kesehatan jiwa dan psikososial pada dirisendiri, keluarga dan masyarakat. Disarankan kepada peserta agar menerapkan Adaptasi Kebiasan baru Covid 19 ini kedalam kehidupan sehari-hari serta menginformasikan kepada angota keluarga untuk menjaga kesehan fisik dan jiwa