bluuebunny/crossref_metadata_2025_split huggingface dataset:
Convexity of charged operators in CFTs with multiple Abelian symmetries
Authors: Palti Eran , Sharon Adar 
Published: September 2022

Abstract
Motivated by the Weak Gravity Conjecture in the context of holography in AdS, it has been proposed that operators charged under global symmetries in CFTs, in three dimensions or higher, should satisfy certain convexity properties on their spectrum. A key element of this proposal is the charge at which convexity must appear, which was proposed to never be parametrically large. In this paper, we develop this constraint in the context of multiple Abelian global symmetries. We propose the statement that the convex directions in the multi-dimensional charge space should generate a sub-lattice of the total lattice of charged operators, such that the index of this sub-lattice cannot be made parametrically large. In the special case of two-dimensional CFTs, the index can be made parametrically large, which we prove by an explicit example. However, we also prove that in two dimensions there always exist convex directions generating a sub-lattice with an index bounded by the current levels of the global symmetry. Therefore, in two dimensions, the conjecture should be slightly modified to account for the current levels, and then it can be proven. In more than two dimensions, we show that the index of the sub-lattice generated by marginally convex charge vectors associated to BPS operators only, can be made parametrically large. However, we do not find evidence for parametric delay in convexity once all operators are considered.
Digitalization of small and medium sized sawmills in Austria: a survey about business processes
Authors: Ranacher L. , Stocker R. , Riegler M. , Schwarzbauer P. , Hesser F. 
Published: September 2022

AbstractThis study investigates the level of digitalization as well as opportunities and challenges from the perspective of sawmill representatives. The level of digitalization of business processes was assessed by a survey on digitalization criteria regarding business processes. The questions dealt with the existence of basic data processing, digitally networked information and communication and digitally networked products and services. Over 700 small and medium sized sawmills were contacted by e-mail or mail using enterprise directories. The response of 87 completed questionnaires was analyzed by means of cluster analysis. The companies were divided into different groups based on their similarity regarding the digitalization criteria. The study identified three clusters: the first cluster (n1 = 35), the “manual small business”, did not reach the first stage of digitalization. The second cluster (n2 = 26), the “automated business”, has partially reached the first stage of digitalization. The third cluster (n3 = 26), the “solid developed” group, has reached the first stage of digitalization as the basic hardware and software is available. The increasing networking of the value chain, the workplace of the future and the increasing individualization of customer requirements are perceived as opportunities. The main barriers are data protection and data security whereas cloud solutions are considered as the biggest risk.
CutFEM based on extended finite element spaces
Authors: Burman Erik , Hansbo Peter , Larson Mats G. 
Published: September 2022

AbstractWe develop a general framework for construction and analysis of discrete extension operators with application to unfitted finite element approximation of partial differential equations. In unfitted methods so called cut elements intersected by the boundary occur and these elements must in general by stabilized in some way. Discrete extension operators provides such a stabilization by modification of the finite element space close to the boundary. More, precisely the finite element space is extended from the stable interior elements over the boundary in a stable way which also guarantees optimal approximation properties. Our framework is applicable to all standard nodal based finite elements of various order and regularity. We develop an abstract theory for elliptic problems and associated parabolic time dependent partial differential equations and derive a priori error estimates. We finally apply this to some examples of partial differential equations of different order including the interface problems, the biharmonic operator and the sixth order triharmonic operator.
Effects of percutaneous coronary intervention on dyspnea in stable coronary artery disease
Authors: Wester Michael , Koll Franziska , Luedde Mark , Langer Christoph , Resch Markus , Luchner Andreas , Müller Karolina , Zeman Florian , Koller Michael , Maier Lars S. , Sossalla Samuel 
Published: September 2022

Abstract
Background
Dyspnea is a frequent symptom in patients with stable coronary artery disease (CAD) and is recognized as a possible angina equivalent.

Objectives
This study was to assess the impact of percutaneous coronary intervention (PCI) on dyspnea, quality of life, and angina pectoris in patients with stable CAD.

Methods
The prospective, multi-center PLA-pCi-EBO-pilot trial included 144 patients with symptomatic stable CAD and successful PCI. The prespecified endpoints angina pectoris (Seattle Angina Questionnaire–SAQ) and dyspnea (NYHA scale) were assessed 6 months after PCI. Predictors for symptomatic improvement were assessed with uni- and multivariable logistic regression analyses.

Results
Patients with concomitant dyspnea had worse SAQ physical limitation scores at baseline (49.5 ± 21.0 vs 58.9 ± 22.0, p = 0.013) but showed no difference for angina frequency or quality of life. Overall, symptomatic burden of angina pectoris and dyspnea was alleviated by PCI. However, patients with concomitant dyspnea had markedly worse scores for physical limitation (78.9 ± 25.0 vs 94.3 ± 10.6, p < 0.001), angina frequency (77.9 ± 22.8 vs 91.1 ± 12.4, p < 0.001), and quality of life (69.4 ± 24.1 vs 82.5 ± 14.4, p < 0.001) after PCI. The prevalence of dyspnea (NYHA class ≥ 2) declined from 73% before PCI to 54%. Of 95 initially dyspneic patients, 57 (60%) improved at least one NYHA class 6 months after PCI. In a multivariable logistic regression analysis, “atypical angina pectoris” was associated with improved NYHA class, whereas “diabetes mellitus” had a negative association.

Conclusion
PCI effectively reduced dyspnea, which is a frequent and demanding symptom in patients with CAD. The German Clinical Trials Register registration number is DRKS0001752 (www.drks.de).

Graphical abstract
Etiologic reclassification of cryptogenic stroke after implantable cardiac monitoring and computed tomography angiography re-assessment
Authors: Mele Francesco , Scopelliti Giuseppe , Manini Arianna , Ferrari Aggradi Carola , Baiardo Matteo , Schiavone Marco , Viecca Maurizio , Ianniello Andrea , Bertora Pierluigi , Forleo Giovanni B. , Pantoni Leonardo 
Published: September 2022

Abstract
Introduction
Different mechanisms may underlie cryptogenic stroke, including subclinical atrial fibrillation (AF), nonstenotic carotid plaques (NCP), and aortic arch atherosclerosis (AAA). In a cohort of cryptogenic stroke patients, we aimed to: (1) evaluate the prevalence of subclinical AF, NCP, and AAA, and reclassify the etiology accordingly; (2) compare the clinical features of patients with reclassified etiology with those with confirmed cryptogenic stroke.

Methods
Data of patients hospitalized for cryptogenic stroke between January 2018 and February 2021 were retrospectively analyzed. Patients were included if they received implantable cardiac monitoring (ICM) to detect subclinical AF. Baseline computed tomography angiography (CTA) was re-evaluated to assess NCP and AAA. Since aortic plaques with ulceration/intraluminal thrombus were considered pathogenetic during the initial workup, only patients with milder AAA were included. Stroke etiology was reclassified as “cardioembolic”, “atherosclerotic”, or “mixed” based on the detection of AF and NCP/AAA. Patients with “true cryptogenic” stroke (no AF, ipsilateral NCP, or AAA detected) were compared with those with reclassified etiology.

Results
Among 63 patients included, 21 (33%) were diagnosed with AF (median follow-up time of 15 months), 12 (19%) had ipsilateral NCP, and 6 (10%) had AAA. Stroke etiology was reclassified in 30 patients (48%): cardioembolic in 14 (22%), atherosclerotic in 9 (14%), and mixed in 7 (11%). Patients with true cryptogenic stroke were younger compared to those with reclassified etiology (p = 0.001).

Discussion
One or more potential covert stroke sources can be recognized in half of the patients with a cryptogenic stroke through long-term cardiac monitoring and focused CTA re-assessment.
Analysis of spot urine biomarkers and association with body weight in Japanese elementary schoolchildren
Authors: Takemoto Nozomi , Millman Jasmine , Uema Tsugumi , Yamakawa Fusae , Okamoto Shiki , Mori Mari , Mori Hideki , Nakamura Koshi , Yamori Yukio , Masuzaki Hiroaki 
Published: September 2022

AbstractChildhood obesity is rapidly increasing worldwide and is largely the consequence of adoption of unhealthy diets excessive in calories and salt (NaCl) as well as devoid in pivotal micronutrients such as potassium (K) and magnesium (Mg). Education-based programs aiming to encourage healthy food knowledge and behaviors are crucial at a young age, and for this purpose, convenient ways to assess daily dietary intake are warranted. We therefore attempted to evaluate the dietary intake of Okinawan schoolchildren in Japan by analyzing a series of biomarkers in morning spot urine samples and explore whether these biomarkers correlate with body weight and a series of metabolic parameters. We enrolled 98 third-grade elementary schoolchildren in Okinawa, Japan. Morning spot urine samples were collected and analyzed using high-performance liquid chromatography (HPLC) to assess dietary intake. We found that estimated daily NaCl intake was higher in obese/overweight children as compared to healthy-weight children (p = 0.0001). There was also a significant positive correlation between body mass index (BMI) and NaCl intake (Spearman) (ρ = 0.45, p < 0.0001) and a negative correlation between BMI and Mg/Cr (ρ =  −0.27, p = 0.01). Furthermore, Na/K ratio was higher in samples collected on Monday (weekend) as compared to samples collected on Thursday or Friday (weekday) (p < 0.0001).Conclusion: Via the use of morning spot urine analyses, our results show that NaCl intake was associated with obesity, and Mg excretion negatively correlated with BMI in Japanese schoolchildren, highlighting the potential role of these micronutrients in maintaining a healthy body weight.

What is Known:•Overweight and obesity are largely due to excessive consumption of calories and positively correlated with salt (NaCl) intake.•Spot urine methods are convenient for assessing the nutritional needs and targeting prevention programs in children.

What is New:•Utilizing morning spot urine analyses, estimated NaCl intake is positively correlated and Mg/Cr negatively correlated with BMI in Okinawan schoolchildren.•As estimated via morning spot urine samples, a greater proportion of children likely exceeds the recommended NaCl intake on the weekend as compared to weekday.
Orthodontic camouflage versus orthodontic-orthognathic surgical treatment in borderline class III malocclusion: a systematic review
Authors: Alhammadi Maged S. , Almashraqi Abeer A. , Khadhi Ahmed Hassan , Arishi Khalid Abdullrahman , Alamir Abdelhamid Aidarous , Beleges Essa Mohammed , Halboub Esam 
Published: September 2022

Abstract
Objective
This systematic review evaluated the available evidence regarding the skeletal, dentoalveolar, and soft tissue effects of orthodontic camouflage (OC) versus orthodontic-orthognathic surgical (OOS) treatment in borderline class III malocclusion patients.

Methods
Eligibility criteria. The included studies were clinical trials and/or follow-up observational studies (retrospective and prospective). Information sources. PubMed, Scopus, Science Direct, Web of Science, Cochrane, and LILACS were searched up to October 2021. Risk of bias. Downs and Black quality assessment checklist was used. Synthesis of results. The outcomes were the skeletal, dentoalveolar, and soft tissue changes obtained from pre- and post-cephalometric measurements.

Results
Included studies. Out of 2089 retrieved articles, 6 were eligible and thus included in the subsequent analyses. Their overall risk of bias was moderate. Outcome results. The results are presented as pre- and post-treatment values or mean changes in both groups. Two studies reported significant retrusion of the maxillary and mandibular bases in OC, in contrast to significant maxillary protrusion and mandibular retrusion with increased ANB angle in OOS. Regarding the vertical jaw relation, one study reported a significant decrease in mandibular plane inclination in OC and a significant increase in OOS. Most of the included studies reported a significant proclination in the maxillary incisors in both groups. Three studies reported a significant proclination of the mandibular incisors in OOS, while four studies reported retroclination in OC.

Conclusion
Interpretation. The OSS has a protrusive effect on the maxillary base, retrusive effect on the mandibular base, and thus improvement in the sagittal relationship accompanied with a clockwise rotational effect on the mandibular plane. The OC has more proclination effect on the maxillary incisors and retroclination effect on the mandibular incisors compared to OOS. Limitation. Meta-analysis was not possible due to considerable variations among the included studies. Owing to the fact that some important data in the included studies were missing, conducting further studies with more standardized methodologies is highly urgent. Registration. The protocol for this systematic review was registered at the International Prospective Register of Systematic Reviews (PROSPERO, No.: CRD42020199591).

Clinical relevance
The common features including skeletal, dental, and soft tissue characteristics of borderline class III malocclusion cases make it more difficult to select the most appropriate treatment modality that can be either OC or OOS. The availability of high-level evidence—systematic reviews—makes the clinical decision much more clear and based on scientific basis rather than personal preference.
Efficient DEM simulations of railway ballast using simple particle shapes
Authors: Suhr Bettina , Six Klaus 
Published: September 2022

AbstractFor complex shaped materials, computational efficiency and accuracy of DEM models are usually opposing requirements. In the literature, DEM models of railway ballast often use very complex and computationally demanding particle shapes in combination with very simple contact laws. In contrast, this study suggests efficient DEM models for railway ballast using simple particle shapes together with a contact law including more physical effects. In previous works of the authors, shape descriptors, calculated in a shape analysis of two types of ballast, were used to construct simple particle shapes (clumps of three spheres). Using such a shape in DEM simulations of compression and direct shear tests, accurate results were achieved only when the contact law included additional physical effects e.g. edge breakage. A parametrisation strategy was developed for this contact law comparing DEM simulations with the measurements. Now, all the constructed simple particle shapes are parametrised allowing to study their suitability and relating their shape descriptors to those of railway ballast. The most suitable particle shapes consist of non-overlapping spheres, thus have a high interlocking potential, and have lowest sphericity and highest convexity values. In a micromechanical analysis of the four best performing shapes, three shapes show similar behaviour on the bulk and the micro-scale, while one shape differs clearly on the micro-scale. This analysis shows, which shapes can be expected to produce similar results in DEM simulations of other tests/load cases. The presented approach is a step towards both efficient and accurate DEM modelling of railway ballast.
Graphic abstract
Infant adoptions in wild bonnet macaques (Macaca radiata)
Authors: Anand Ashvita , Balakrishna Nagarathna , Singh Mewa , Isbell Lynne A. , Sirigeri Sindhuja , Saikia Anushka , Arlet Małgorzata E. 
Published: September 2022

AbstractThough uncommon, adoption of orphaned infants has been observed in both wild and captive non-human primates. In two groups of wild bonnet macaques (Macaca radiata), we observed five instances of infants being cared for after they lost their mothers at a pre-weaning age (< 6 months). Orphaned infants had one or more caregivers (juvenile, subadult, and adult female or male) involved in carrying, grooming, hugging, and protecting them. Adoption did not appear to be related to the age/sex class of the infant, or directly to the mother’s rank. Although the dominance rank of the mother of an orphaned infant did not have a direct effect on orphan survivorship, it determined the number of caregivers available to the orphaned infant, and infant survivorship was positively related to the number of caregivers of the orphaned infant. Thus, survivorship was likely a function of the mother’s sociality. Two other infants born to high-ranking mothers were also adopted by more individuals and survived longer than the infants of low-ranking mothers.
Machine Learning for Improving Surface-Layer-Flux Estimates
Authors: McCandless Tyler , Gagne David John , Kosović Branko , Haupt Sue Ellen , Yang Bai , Becker Charlie , Schreck John 
Published: September 2022

AbstractFlows in the atmospheric boundary layer are turbulent, characterized by a large Reynolds number, the existence of a roughness sublayer and the absence of a well-defined viscous layer. Exchanges with the surface are therefore dominated by turbulent fluxes. In numerical models for atmospheric flows, turbulent fluxes must be specified at the surface; however, surface fluxes are not known a priori and therefore must be parametrized. Atmospheric flow models, including global circulation, limited area models, and large-eddy simulation, employ Monin–Obukhov similarity theory (MOST) to parametrize surface fluxes. The MOST approach is a semi-empirical formulation that accounts for atmospheric stability effects through universal stability functions. The stability functions are determined based on limited observations using simple regression as a function of the non-dimensional stability parameter representing a ratio of distance from the surface and the Obukhov length scale (Obukhov in Trudy Inst Theor Geofiz AN SSSR 1:95–115, 1946), $$z/L$$

z
/
L

. However, simple regression cannot capture the relationship between governing parameters and surface-layer structure under the wide range of conditions to which MOST is commonly applied. We therefore develop, train, and test two machine-learning models, an artificial neural network (ANN) and random forest (RF), to estimate surface fluxes of momentum, sensible heat, and moisture based on surface and near-surface observations. To train and test these machine-learning algorithms, we use several years of observations from the Cabauw mast in the Netherlands and from the National Oceanic and Atmospheric Administration’s Field Research Division tower in Idaho. The RF and ANN models outperform MOST. Even when we train the RF and ANN on one set of data and apply them to the second set, they provide more accurate estimates of all of the fluxes compared to MOST. Estimates of sensible heat and moisture fluxes are significantly improved, and model interpretability techniques highlight the logical physical relationships we expect in surface-layer processes.
Heat flux estimation from borehole temperatures acquired during logging while tripping: a case study with the sea floor drill rig MARUM-MeBo
Authors: Freudenthal T. , Villinger H. , Riedel M. , Pape T. 
Published: September 2022

AbstractDuring trip out of the drill string at the end of a drilling operation (logging while tripping) borehole temperatures can be measured without the need for additional operational time. A simple interpretation of the measured borehole temperatures is difficult due to the interfering influences of the drilling operations, mainly due to flushing the borehole during drilling. In this study, we present borehole temperature data from drilling campaigns with the sea floor drill rig MARUM-MeBo200 at the Danube Deep Sea Fan (Black Sea) and west of Taiwan (South China Sea). The temperature measurements were conducted with a PT1000 temperature sensor which is integrated in a memory acoustic borehole logging tool. We developed a modeling approach in order to simulate the drilling perturbations and subsequent evolution of the temperature field within the borehole. By fitting the model data to the measured time dependent temperature depth profiles, we estimated the undisturbed heat flux at the drill sites. This study shows that knowledge of the pattern of drilling operations with alternating phases of drilling/flushing and drill string handling is crucial for comparing temperatures measured during logging while tripping and simulated temperatures.
Phenotypic Variants of Azole-Resistant Aspergillus Fumigatus that Co-exist in Human Respiratory Samples are Genetically Highly Related
Authors: Abdolrasouli Alireza , Rhodes Johanna L. 
Published: September 2022

AbstractRespiratory specimens obtained from patients with chronic forms of aspergillosis contain phenotypic variants of azole-resistantAspergillus fumigatus(ARAF) that co-exist in the airway. Here we aimed to study whether phenotypic variants of ARAF that co-exist in clinical specimens were genetically distinct. A panel of six phenotypic variants of ARAF cultured from two sputum samples collected from two patients with chronic aspergillosis were included. Preliminary identification of all isolates was obtained using MALDI–ToF mass spectrometry and confirmed by AsperGenius®real-time PCR assay. Antifungal susceptibility testing was determined using EUCAST E.Def 9.3 microbroth dilution. Genomic DNA libraries were constructed with the Illumina TruSeq Nano kit. Prepared whole-genome libraries were sequenced on an Illumina HiSeq 2500. Whole genome data were converted into presence/absence of a SNP with respect to the Af293 reference genome. Colonies of ARAF that co-existed in one respiratory sample demonstrated marked phenotypic diversity. Twocyp51Apolymorphisms were found among azole-resistant isolates: TR34/L98H/T289A/I364V/G448S was consistently present in four variants with a pan-azole resistant phenotype and TR34/L98H was detected in two variants (itraconazole MIC > 16 mg/L). WGS typing showed that despite marked phenotypic variation, each sample contained a population of highly genetically related azole-resistantA. fumigatusvariants. Our SNP analysis suggest that mechanisms additional to genetic-based variation are responsible for phenotypic diversity. Our data demonstrate that the phenotypic variants of ARAF that co-exist in clinical specimens are highly clonal and strongly suggest their origination from a single common ancestor.