bluuebunny/crossref_metadata_2025_split huggingface dataset:
İSLÂM ÖNCESİ ARAP TARİHİNİ YANSITMASI BAKIMINDAN KAYA RESİMLERİ
Authors: TEMİR Hakan 
Published: February 2022

Yazı, insan ilişkilerini mikro sevide yansıtan bir araç olduğundan “tarih yazıyla başlar” tezi haklı bir söylemdir. Lakin yazıdan önce de insan vardı ve varlığını bir şekilde duyurmak, sonraki nesillere nasihatte bulunmak ya da hiç değilse iç dünyalarını yansıtmak isteyen kimseler; malzeme yetersizliğine aldırış etmeden taşların üzerine resimler çizmişlerdir ki bunlar alfabeye dayalı olmayan bir aktarım sistematiğinin ürünleridir. Yazıdan önce veya sonra hiç fark etmez, insan ilişkilerini kompozisyonlar hâlinde sunan kaya resimleri 19. yüzyıldan itibaren dikkatleri üzerine topladığından arkeologlar, taşlar üzerine resmedilen geçmişi keşfetmeye yöneldiler. Dünya genelindeki bu zengin miras, birçok coğrafyanın tarihini aydınlatmaya ve bazı genel kanaatleri değiştirmeye namzettir.
Tarihî materyal mahiyeti taşıyan kaya resimleri, Arap Yarımadası’na gelişleri çok eski olan Arapların tarihini aydınlatmada da argümandır. Kısmen dinî haberler ve İslâmî dönemdeki kurgularla anlatılan kadim Arap tarihi, sınırlı bilgilerden ibaret olduğundan bunların bir milletin uzak geçmişini aydınlatmaya yeterli gelmeyeceğini artık kabul etmek gerekir. Tarihteki bu boşluk, son birkaç asır boyunca sürdürülen arkeolojik kazılar sayesinde doldurulabilir. Zira uzman arkeologların öncülüğünde yürütülen kazılarda bugünkü Suudi Arabistan’da 4 bin sit bölgesi ve 1.500 civarında kaya resmi alanı keşfedilmiştir. Yarımadanın farklı yerlerinde ortaya çıkan bu zengin miras, birçok kaya yüzeyinde belirgin veya yarı belirgin şekilde durarak ulusal kimliğin tespiti de dâhil olmak üzere çeşitli konularda işe yarayacaktır. Dolayısıyla bu çalışmada İslâm öncesi Arap tarihini gün yüzüne çıkarmada kaya resimlerinin konumunu belirlemek amacıyla kaya resimleri tabirinden başlayarak ören yerleri, kayalarda bulunan şekil ve yazıların değerlenmesi ile bunların tarihe olan katkıları üzerinde durulacaktır. Arkeolojik buluntular henüz yeni bir uğraş olduğundan araştırmada daha çok güncel kaynaklardan ve web sitelerinden yararlanılacaktır.
Transradial Retrograde Percutaneous Coronary Intervention of Chronic Total Occlusion via an Ipsilateral Septal Collateral Using a Single Guiding Catheter: A Case Report
Authors: Liu Xiaogang , Zhang Jing , Zhang Hong , Zhang Peng , Fu Naikuan 
Published: February 2022

BackgroundWith the development of specialized equipment and the retrograde technique, success rates for percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) have increased from 60 to 90% in the past 10 years. Performing PCI via a collateral channel from the contralateral artery, using two guiding catheters, is usually the preferred approach to retrograde CTO-PCI. In the case described in this report, only the ipsilateral septal collateral artery from the proximal occluded left anterior descending (LAD) artery was available. The procedure can be performed successfully from radial artery access using a single guiding catheter.Case SummaryA 57-year-old patient, with a history of anterior and inferior myocardial infarction and previous PCI, underwent a planned coronary arteriography due to his complaints of typical angina symptoms. Coronary angiography revealed stent occlusion located mid-LAD and severe in-stent restenosis in the distal right coronary artery (RCA). A proximal septal branch was supplying the distal LAD retrogradely. After repeated failed attempts at antegrade PCI for the LAD's CTO, the retrograde approach was tried. This intervention finally succeeded through the ipsilateral septal collateral. It was performed via a single radial-artery access throughout the whole process. Post-operatively, the patient had no complications and was stable at 1-year follow-up.ConclusionThe transradial approach to retrograde PCI for CTO via an ipsilateral septal collateral using a single guiding catheter is feasible and safe in appropriately selected cases.
Improvements of the Sub-Seasonal Precipitation Predicted by the BCC_S2S Forecast System Over Eastern China in Summer Using the Singular Value Decomposition Bias Correction Method
Authors: Fu Zhipeng , Huang Anning , Guo Qu 
Published: February 2022

A bias correction scheme has been developed based on the singular value decomposition (SVD) analysis in this study, and it is further validated and used to improve the skill of sub-seasonal precipitation over Eastern China in summer predicted by the Beijing Climate Center sub-seasonal to seasonal forecast system (BCC_S2SFS). Results show that the BCC_S2SFS prediction skill of summer precipitation over Eastern China at the sub-seasonal scale is up to 1 days in advance and exhibits clear regional and inter-annual differences. Further adopting the bias correction scheme can significantly improve the skill of BCC_S2SFS in predicting the sub-seasonal precipitation over Eastern China in summer with different lead time especially longer than 10 days. Compared to the original prediction of BCC_S2SFS, the temporal (spatial) correlation coefficient between the bias corrected predictions and observations over Eastern China can be increased by 0.15, 0.55, and 0.56 (0.14, 0.17, and 0.19) during the forecast lead time of 0–10, 11–20, and 21–30 days, respectively. The bias correction scheme developed in this study shows large potential application prospects in the operational forecast.
Sex Disparities in the Association of Serum Uric Acid With Kidney Stone: A Cross-Sectional Study in China
Authors: Xu Jin-Zhou , Lu Jun-Lin , Hu Liu , Xun Yang , Wan Zheng-Ce , Xia Qi-Dong , Qian Xiao-Yuan , Yang Yuan-Yuan , Hong Sen-Yuan , Lv Yong-Man , Wang Shao-Gang , Lei Xiao-Mei , Guan Wei , Li Cong 
Published: February 2022

Background and AimsUrolithiasis is characterized by high rates of prevalence and recurrence. Hyperuricemia is related to various diseases. We hope to determine the association between serum uric acid (UA) level and kidney stone (KS).MethodsIn this population-based cross-sectional study, a total of 82,017 Chinese individuals who underwent a comprehensive examination in 2017 were included. The KS was diagnosed based on ultrasonography examination outcomes. Fully adjusted odds ratio (OR) for KS, and mean difference between the two groups were applied to determine the association of UA level with KS.ResultsAmong the 82,017 participants included in this study (aged 18~99 years), 9,435 participants (11.5%) are diagnosed with KS. A proportion of 56.3% of individuals is male. The mean UA level of overall participants is 341.77 μmol/L. The participants with KS report higher UA level than the participants without KS [mean UA level 369.91 vs. 338.11 μmol/L; mean difference (MD), 31.96 (95% CI, 29.61~34.28) μmol/L]. In men, the OR for KS significantly increases from 330 μmol/L UA level. Every 50 μmol/L elevation of UA level increases the risk of KS formation by about 10.7% above the UA level of 330 μmol/L in men. The subgroup analysis for male is consistent with the overall result except for the participants presenting underweight [adjusted OR, 1.035 (0.875~1.217); MD, −5.57 (−16.45~11.37)], low cholesterol [adjusted OR, 1.088 (0.938~1.261); MD, 8.18 (−7.93~24.68)] or high estimated glomerular filtration rate (eGFR) [adjusted OR, 1.044 (0.983~1.108); MD, 5.61 (−1.84~13.36)]. However, no significant association is observed in women between UA and KS either in all female participants or in female subgroups.ConclusionAmong Chinese adults, UA level is associated with KS in a dose-response manner in men but not in women. However, the association becomes considerably weak in male participants with malnutrition status.
Impact of COVID-19 Infection Among Heart Transplant Recipients: A Southern Brazilian Experience
Authors: Scolari Fernando Luis , Hastenteufel Laura Caroline Tavares , Einsfeld Lídia , Bueno Julia , Orlandin Letícia , Clausell Nadine , Goldraich Lívia Adams 
Published: February 2022

PurposeThe coronavirus-2019 (COVID-19) infection is associated with a high risk of complications and death among heart transplant recipients. However, most cohorts are from high-income countries, while data from Latin America are sparse.MethodsThis is a retrospective cohort of heart transplant recipients followed at a hospital in Rio Grande do Sul, Brazil, between March 1st 2020 and October 1st 2021.ResultsOf the 62 heart transplant recipients on follow-up, 21 (34%) were infected by COVID-19, 58 (36–63) years of age, 67% male, body mass index of 26 (23-29) kg/m2, 48% with hypertension, 43% with chronic kidney disease, 5% with diabetes, within 2 (1–4) years of post-transplant follow-up. At presentation, the main symptoms were fever (62%), myalgia (33%), cough (33%), headache (33%), and dyspnea (19%). Hospitalization was required for 13 (62%) patients, with a time from first symptoms to the admission of 5 (1–12) days. In 38%, supplementary oxygen was needed, 19% required intensive care, and 10% mechanical ventilation. Three (14%) were infected after at least a first dose of COVID-19 vaccine. The main complications were bacterial pneumonia (38%), renal replacement therapy (19%), sepsis (10%) and venous thromboembolism (10%). Immunosuppression therapy was modified in 48%, with a reduction in the majority (89%). Two (10%) patients died in the hospital due to refractory hypoxemia and multiple organ dysfunction. The incidence of COVID-19 among transplant patients was comparable to the general population in the State of Rio Grande do Sul with a peak in December 2020.ConclusionHeart transplant recipients shown a high rate of COVID-19 infection in Southern Brazil, with typical symptom presentation in most cases. There was an elevated rate of hospitalization, supplementary oxygen support, and complications. In-hospital lethality among infected heart transplanted recipients was similar to previously reported data worldwide despite the high rates of infection in Latin America.
A Real-World Observation of Antipsychotic Effects on Brain Volumes and Intrinsic Brain Activity in Schizophrenia
Authors: Chen Yifan , Womer Fay Y. , Feng Ruiqi , Zhang Xizhe , Zhang Yanbo , Duan Jia , Chang Miao , Yin Zhiyang , Jiang Xiaowei , Wei Shengnan , Wei Yange , Tang Yanqing , Wang Fei 
Published: February 2022

BackgroundThe confounding effects of antipsychotics that led to the inconsistencies of neuroimaging findings have long been the barriers to understanding the pathophysiology of schizophrenia (SZ). Although it is widely accepted that antipsychotics can alleviate psychotic symptoms during the early most acute phase, the longer-term effects of antipsychotics on the brain have been unclear. This study aims to look at the susceptibility of different imaging measures to longer-term medicated status through real-world observation.MethodsWe compared gray matter volume (GMV) with amplitude of low-frequency fluctuations (ALFFs) in 89 medicated-schizophrenia (med-SZ), 81 unmedicated-schizophrenia (unmed-SZ), and 235 healthy controls (HC), and the differences were explored for relationships between imaging modalities and clinical variables. We also analyzed age-related effects on GMV and ALFF values in the two patient groups (med-SZ and unmed-SZ).ResultsMed-SZ demonstrated less GMV in the prefrontal cortex, temporal lobe, cingulate gyri, and left insula than unmed-SZ and HC (p &lt; 0.05, family-wise error corrected). Additionally, GMV loss correlated with psychiatric symptom relief in all SZ. However, medicated status did not influence ALFF values: all SZ showed increased ALFF in the anterior cerebrum and decreased ALFF in posterior visual cortices compared with HC (p &lt; 0.05, family-wise error corrected). Age-related GMV effects were seen in all regions, which showed group-level differences except fusiform gyrus. No significant correlation was found between ALFF values and psychiatric symptoms.ConclusionGMV loss appeared to be pronounced to longer-term antipsychotics, whereby imbalanced alterations in regional low-frequency fluctuations persisted unaffected by antipsychotic treatment. Our findings may help to understand the disease course of SZ and potentially identify a reliable neuroimaging feature for diagnosis.
Antithrombin III Defi ciency: Diagnosis, Therapy and Management of Patients with Pregnancy
Authors: Кабаева Е.Н. 
Published: February 2022

Дефицит антитромбина 3 (АТ3) является редкой тромбофилией высокого риска с частотой выявления 0,2-0,4%. Тромботические осложнения у лиц с дефицитом АТ3 составляют от 15% до 100% случаев в различных семьях. При беременности риск тромботических осложнений у данной группы пациентов увеличен в 30 раз. Дефицит АТ значительно увеличивает риск тромбоза глубоких вен или тромбоэмболии легочной артерии (ТЭЛА). Несмотря на антикоагулянтную терапию лечебными дозами гепарина во время беременности и после родоразрешения, женщины с дефицитом АТ могут быть подвержены риску развития венозных тромбоэмболий (ВТЭ), в том числе со смертельным исходом. Терапия таких пациенток всегда требует совместной работы врачей-акушеров, специалистов по тромбозу и гемостазу. Ввиду редкости данной патологии четких клинических протоколов на сегодняшний день не существует. Рекомендации по лечению базируются на мнениях экспертов, отдельных клинических исследованиях и описаниях клинических случаев. Тромбофилические состояния играют большую роль в генезе многих осложнений беременности. Несмотря на большое количество работ, посвященных изучению различных факторов свертывания, до сих пор до конца не определена тактика ведения беременности при некоторых формах тромбофилий, особенно редко встречающихся. С целью систематизации подходов к терапии и ведению беременности в различных клинических ситуациях и обсуждения роли концентрата АТ3 написана данная статья.
Antithrombin 3 deficiency is a rare high-risk thrombophilia with a prevalence of 0.2-0.4%. Thrombotic complications in individuals with AT3 deficiency range from 15% to 100% in different families. During pregnancy, the risk of thrombotic complications in this group of patients is 30 times higher. AT deficiency significantly increases the risk of deep vein thrombosis or pulmonary embolism (PE). Despite anticoagulant therapy with therapeutic doses of heparin during pregnancy and after delivery, women with AT deficiency may be at risk of developing VTE, including death. The therapy these patients always require the join work of doctors - obstetricians, specialists at thrombosis and hemostasis. There are no clear clinical protocols due to the rarity of this pathology. Treatment recommendations are based on expert opinion, selected clinical studies and case reports. In order to systematize approaches to the therapy and management of pregnancy in various clinical situations and to discuss the role of antithrombin 3 concentrate, this article has been written.
Prevention of Complications After Termination Pregnancy in the First Trimester (Literature Review)
Authors: Воскресенский С.Л. , Грудницкая Е.Н. , Волотовская А.В. , Волковец Э.Н. , Мосько П.Л. 
Published: February 2022

В обзоре приведены данные о количестве выполняемых абортов в мире и Республике Беларусь. Рассмотрены существующие методы прерывания беременности. Освещены ранние, отсроченные и отдаленные осложнения после хирургического и медикаментозного прерывания беременности. Отмечается, что любой способ досрочного прекращения беременности отражается на здоровье женщины. Подробно описаны постабортные нарушения репродуктивного, соматического и психического здоровья. Особое внимание уделено ранней реабилитации женщин после аборта и профилактике постабортных осложнений. Подробно рассмотрена эффективность приема комбинированных оральных контрацептивов и физиотерапии после прерывания беременности, показана более высокая результативность комплексной реабилитации.
The review provides data on the number of abortions performed in the world and the Republic of Belarus. The existing methods of termination of pregnancy are considered. The article covers early, delayed and long-term complications after surgical and medical termination of pregnancy. It is noted that any method of early termination of pregnancy affects the health of a woman. Postabortem disorders of reproductive, somatic, and mental health are described in detail. Special attention is paid to the early rehabilitation of women after abortion and the prevention of post-abortion complications. The effectiveness of taking combined oral contraceptives and physical therapy after termination of pregnancy is considered in detail, and the higher effectiveness of complex rehabilitation is shown.
Treatment and Prevention of Early Pregnancy Loss in Women with Adenomyosis
Authors: Трохимович О.В. , Борисюк О.Ю. , Чубей Г.В. 
Published: February 2022

В статье рассмотрены особенности фармакодинамики интравагинального и перорального путей лечения препаратами микронизированного прогестерона. Представлены результаты использования препарата микронизированного прогестерона Прогинорм Геста на этапе прегравидарной подготовки женщин с аденомиозом. Обосновано интравагинальное применение микронизированного прогестерона Прогинорм Геста с целью профилактики и лечения ранней потери беременности у женщин с аденомиозом. Установлено, что назначение Прогинорм Геста в первом триместре беременности предупреждает потерю беременности у женщин с аденомиозом, а также является эффективным средством лечения угрозы аборта.
The article discusses the features of the pharmacodynamics of intravaginal and oral treatment with micronized progesterone drugs. The results of the use of micronized progesterone preparations Proginorm Gesta at the stage of pregravid preparation of women with adenomyosis are presented. The intravaginal use of micronized progesterone Proginorm Gesta is substantiated for the prevention and treatment of early pregnancy loss in women with adenomyosis. It has been established that the appointment of Proginorm Gesta in the first trimester of pregnancy prevents pregnancy loss in women with adenomyosis, and is also an effective treatment for the threat of abortion.
Post-COVID Syndrome Variety and Possibilities of Correction of Post-Infectious Immunosuppression
Authors: Якубова Л.В. , Смирнова Л.Н. 
Published: February 2022

В обзорной статье приводятся определение пост-COVID-синдрома и его классификации. Основные клинические проявления пост-COVID-синдрома включают в себя множество состояний и симптомов, частота проявлений которых варьирует в зависимости от тяжести острой инфекции и периода наблюдения. Наиболее распространенный симптом пост-COVID-синдрома - усталость, встречающаяся с частотой от 17,5% до 72%. По данным Dennis A. и соавт., МРТ выявила поражение хотя бы одного органа в 70% случаев пост-COVID-синдрома через 4 месяца после выздоровления от острой инфекции. Длительное воспаление, иммунная дисрегуляция играют ключевую роль в развитии большинства пост-COVID-проявлений, безусловно, являясь не единственным патофизиологическим механизмом их развития. Если воспалительный ответ слишком подавлен, то пациент, сумев «пережить» первоначальный гипервоспалительный цитокиновый шторм и прогрессирование полиорганной недостаточности, может вступить в стадию затяжной иммуносупрессии, известной как синдром стойкого воспаления, иммуносупрессии и катаболизма, что является одной из предполагаемых причин стойкого пост-COVID-синдрома. Приведена работа, в которой рассматривается возможность применения в лечении инфекции SARS-CoV-2 инозина пранобекса, который зарегистрирован как противовирусный иммуномодулирующий препарат более чем в 70 странах мира.
The review article provides the definition of post-COVID syndrome and its classification. The main clinical manifestations of post-COVID syndrome include many conditions and symptoms, the frequency of which varies depending on the severity of the acute infection and the observation period. The most common symptom of post-COVID syndrome is fatigue, ranging from 17.5% to 72%. According to Dennis A. et al., the MRI revealed damage to at least one organ in 70% of post- COVID cases in 4 months after recovery from acute infection. Prolonged inflammation and immune dysregulation play a key role in the development of the majority of post-COVID manifestations, certainly not being the only pathophysiological mechanism of its development. If the inflammatory response is too suppressed, the patient, having managed to "survive" the initial hyperinflammatory cytokine storm and the progression of multiple organ failure, may enter the stage of protracted immunosuppression known as persistent inflammation, immunosuppression and catabolism syndrome, which is one of the alleged reasons of persistent post-COVID syndrome. The work is presented, in which the possibility of using inosine pranobex, which is registered as an antiviral immunomodulatory drug in more than 70 countries of the world, is considered in the treatment of SARS-CoV-2 infection.
Choice of Low-Intensity Laser Radiation Parameters for Use in Complex Therapy of Chronic Generalized Periodontitis
Authors: Бобкова И.Л. , Зиновенко О.Г. 
Published: February 2022

Хронический генерализованный пародонтит характеризуется высокой распространенностью среди взрослого населения. Актуален поиск новых действенных методов лечения данной патологии. Одним из путей повышения эффективности является применение комплексных методов лечения, основанных на сочетании лазерного излучения с медикаментозным воздействием. Целью работы являлся выбор параметров низкоинтенсивного лазерного излучения (НИЛИ) для использования в комплексной терапии хронического генерализованного пародонтита.
Periodontal diseases are widely spread among the adult population. A search of new effective methods of treating gingivitis and periodontitis is actual.One of the ways to improve the efficiency of treating this pathology is the use of complex methods of treatment based on a combination of laser radiation and medicinal effect. The aim of the study was to investigate the effect of low intensity laser radiation for using in the complex therapy of chronic generalized periodontitis.
Methods of Treating Tooth Cracks
Authors: Новак Н.В. 
Published: February 2022

В статье изложены разработанные на кафедре терапевтической стоматологии БелМАПО методы лечения трещин постоянных зубов. Данные статьи основаны на результатах научных исследований сотрудников кафедры. Приведены показания и противопоказания к лечению трещин твердых тканей зубов. Внедрение в практику рекомендаций по лечению трещин будет способствовать повышению эффективности лечения зубов, восстановлению утраченных твердых тканей с учетом индивидуальных особенностей зубов пациента, а также профилактике возникновения и прогрессирования трещин эмали и дентина.
The article describes the methods of treatment of cracks of permanent teeth developed at the Department of Therapeutic Dentistry of Belarusian Medical Academy of Postgraduate Education. These articles are based on the results of scientific research of the employees of the department. Indications and contraindications to treatment of cracks of hard tissues of teeth are given. The introduction of recommendations for the treatment of cracks will contribute to improving the effectiveness of dental treatment,restoring lost solid tissues taking into account the individual features of the patient’s teeth, as well as preventing the occurrence and progression of enamel and dentin cracks.