bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sentiment analysis on social media tweets using dimensionality reduction and natural language processing
Authors: Omuya Erick Odhiambo , Okeyo George , Kimwele Michael 
Published: October 2022

AbstractSocial media has been embraced by different people as a convenient and official medium of communication. People write or share messages and attach images and videos on Twitter, Facebook and other social media platforms. It therefore generates a lot of data that is rich in sentiments. Sentiment analysis has been used to determine the opinions of clients, for instance, relating to a particular product or company. Lexicon and machine learning approaches are the strategies that have been used to analyze these sentiments. The performance of sentiment analysis is, however, distorted by noise, the curse of dimensionality, the data domains and the size of data used for training and testing. This article aims at developing a model for sentiment analysis of social media data in which dimensionality reduction and natural language processing with part of speech tagging are incorporated. The model is tested using Naïve Bayes, support vector machine, and K‐nearest neighbor algorithms, and its performance compared with that of two other sentiment analysis models. Experimental results show that the model improves sentiment analysis performance using machine learning techniques.
A Guideline Value for Dioxin-Like Compounds in Marine Sediments
Authors: Manning Therese , Batley Graeme E. 
Published: October 2022

Abstract
Sediments to be dredged as part of the installation of a harbor crossing in Sydney, Australia, contained measurable concentrations of dioxin-like compounds. To assess the suitability of these sediments for ocean disposal, a defensible sediment quality guideline value (SQGV) for dioxin-like compounds, expressed as pg toxic equivalent (TEQ)fish/g dry weight, was required. There were deemed to be too many uncertainties associated with a value derived using effects data from field studies. A similar issue was associated with values based on equilibrium partitioning from sediment to pore water, largely associated with the wide range of reported sediment:water partition coefficients. Greater certainty was associated with the use of a tissue residue approach based on equilibrium partitioning between sediment and organisms determined using tissue concentrations in fish, the most sensitive aquatic biota, and biota:sediment accumulation factors. The calculation of an appropriate SQGV used data for dioxin-like compounds in both fish and sediments from Sydney Harbor. A conservative SQGV for dioxin-like compounds of 70 pg TEQ/g dry weight was deemed to be adequately protective of biota that might be exposed to these contaminants in sediments at the ocean spoil ground. The approach is transferable to similar situations internationally. Environ Toxicol Chem 2023;42:257–271. © 2022 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.
Point‐of‐care CRISPR/Cas biosensing technology: A promising tool for preventing the possible COVID‐19 resurgence caused by contaminated cold‐chain food and packaging
Authors: Zhang Xianlong , Yang Yan , Cao Juanjuan , Qi Zihe , Li Guoliang 
Published: October 2022

AbstractThe ongoing coronavirus disease 2019 (COVID‐19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has caused great public health concern and has been a global threat due to its high transmissibility and morbidity. Although the SARS‐CoV‐2 transmission mainly relies on the person‐to‐person route through the respiratory droplets, the possible transmission through the contaminated cold‐chain food and packaging to humans has raised widespread concerns. This review discussed the possibility of SARS‐CoV‐2 transmission via the contaminated cold‐chain food and packaging by tracing the occurrence, the survival of SARS‐CoV‐2 in the contaminated cold‐chain food and packaging, as well as the transmission and outbreaks related to the contaminated cold‐chain food and packaging. Rapid, accurate, and reliable diagnostics of SARS‐CoV‐2 is of great importance for preventing and controlling the COVID‐19 resurgence. Therefore, we summarized the recent advances on the emerging clustered regularly interspaced short palindromic repeats (CRISPR)/Cas system‐based biosensing technology that is promising and powerful for preventing the possible COVID‐19 resurgence caused by the contaminated cold‐chain food and packaging during the COVID‐19 pandemic, including CRISPR/Cas system‐based biosensors and their integration with portable devices (e.g., smartphone, lateral flow assays, microfluidic chips, and nanopores). Impressively, this review not only provided an insight on the possibility of SARS‐CoV‐2 transmission through the food supply chain, but also proposed the future opportunities and challenges on the development of CRISPR/Cas system‐based detection methods for the diagnosis of SARS‐CoV‐2.
Digital sales channels and the relationship between product and international diversification: Evidence from going digital retail MNEs
Authors: Batsakis Georgios , Konara Palitha , Theoharakis Vasilis 
Published: October 2022

AbstractResearch SummaryWe argue that in the era of e‐commerce, retail firms can simultaneously grow their product and international portfolio by adopting a multichannel strategy, that is, using digital and physical channels. Drawing on the resource bundling perspective, we argue that the previously advocated negative relationship between product and international diversification is mitigated by the retail firm's digital sales intensity. By separately examining product and international diversification across digital and physical channels, we find that while increased product diversification in physical channels relates negatively with international diversification in both physical and digital channels, increased product diversification in digital channels relates positively with international diversification in both channels. Our hypotheses are tested against a sample of 122 born physical ‐ going digital retail MNEs over the period 2006–2016.Managerial SummaryThe decision on how firm resources should be allocated for growing a firm's product and international scope has been a continuing debate in corporate strategy. While our research supports the conventional wisdom that product portfolio growth relates negatively to international market growth, we show that firms which increase their digital sales are able to mitigate the costs associated with this relationship. Based on longitudinal data of some of the world's largest retail MNEs, our research shows that retail firms with increased digital sales activity are more capable of mutually benefiting from simultaneously growing their product portfolio and international market presence. Therefore, if a retail firm aims at simultaneously growing its product portfolio and international market presence, it is advisable that they increase their proportion of digital sales (i.e., e‐commerce activity).
Bidirectional intimate partner violence: Evidence from a list experiment in Kenya
Authors: Castilla Carolina , Murphy David M. A. 
Published: October 2022

AbstractIntimate Partner Violence (IPV) continues to be a major public health concern that can both respond to economic policies and affect economic outcomes. Few studies regarding IPV, however, take a gender inclusive approach towards its identification. Using a sample of both men and women from rural Kenya, we are the first, to our knowledge, to conduct a list experiment with cohabiting married couples to identify the prevalence of physical violence on both men and women. We find that 14 percent of respondents agree with the statement “my spouse regularly hits me”. In contrast to other survey evidence that uses direct elicitation, we find no differences in the prevalence of male‐to‐female and female‐to‐male violence. We provide supporting evidence that bidirectional IPV accounts for the lack of gender differences. A complete understanding of the typology of IPV can be crucial for policies seeking IPV reduction.
Evaluation of the definition of hyperdynamic circulation in patients with cirrhosis and ascites
Authors: Ripoll Cristina , Ibáñez‐Samaniego Luis , Neumann Beatrix , Vaquero Javier , Greinert Robin , Bañares Rafael , Zipprich Alexander 
Published: October 2022

Abstract
The aim of this study was to evaluate potential criteria for defining hyperdynamic circulation in patients with cirrhosis according to the severity of ascites and its association with the activation of vasoactive systems and markers of systemic inflammation. Cross‐sectional study of patients with cirrhosis and right heart catheter measurement from two different academic centers. We evaluated systemic vascular resistance (SVR)/cardiac output (CO) according to ascites severity. The first substudy evaluated the possible definition, the second validated the findings, and the third evaluated the possible mechanisms. Comparisons were performed by means of t test, Mann–Whitney U test, and analysis of variance. Finally, linear regression curves were adjusted to evaluate the relationship between CO and SVR according to the severity of ascites and compensated or decompensated stage of cirrhosis. The study included 721 patients (substudy 1, n = 437; substudy 2, n = 197; substudy 3, n = 87). Hyperdynamic circulation (HC), defined by absolute cutoffs, had no association with the presence or severity of ascites in the first two cohorts. No association was observed between HC with renin, aldosterone, or markers of bacterial translocation. Comparison of linear regression curves showed a shift of the CO–SVR relationship to the left in patients with refractory ascites (p < 0.001) compared to patients without ascites as well as to patients with decompensated cirrhosis (p = 0.002). Conclusion: HC according to the traditional concept of high CO and low SVR is not always present in ascites. Evaluation of the CO–SVR relationship according to the severity of ascites shows a shift to the left, suggesting that the presence of HC would be defined by this shift, independent of absolute values.
Maladaptation in air traffic management: Development of a Human Factors methods framework
Authors: Foster Craig J. , Plant Katherine L. , Stanton Neville A. 
Published: October 2022

AbstractHuman Factors methods play a key role in challenging assumptions, analyzing interactions, and informing decision‐making in complex sociotechnical systems and organizations that manage safety risks. Structured methodological approaches also have a role to play in better understanding properties of systems such as adaptation. Adaptation is increasingly recognized as being an important feature that supports the production of safety in complex sociotechnical systems. A safety management intervention, introduced to address a real risk in UK air traffic control but which resulted in unanticipated, maladaptive, and emergent effects, is analyzed using the Hierarchical Task Analysis, Systems Theoretic Accident Model and Processes, Functional Resonance Analysis Method, Human Factors Analysis and Classification System, Cognitive Work Analysis, Critical Decision Method, and Event Analysis of Systemic Teamwork Methods. The results from the application of each of the methods are presented and the different perspectives on adaptation that the methods provide are compared. A methodological framework is presented that has the potential to explore the factors of adaptation across the organizational hierarchy and assist safety practitioners in supporting decision makers in safety‐related organizations.
Mechanisms of epigenetic regulation of transcription by lncRNAs in plants
Authors: Tremblay Benjamin J.M. , Qüesta Julia I. 
Published: October 2022

AbstractLong noncoding RNAs (lncRNAs) are an ubiquitous feature of eukaryotic genomes and in recent decades have been shown to be highly abundant and varied. Many prominent examples have been described as having essential roles in regulating the expression of genes in different developmental and environmental contexts. As a result, much work has been done on elucidating the mechanisms by which they modulate the expression of protein coding genes. In this review, we focus on those which have been characterized in plants. We specifically examine common epigenetic mechanisms that regulate gene expression at the level of transcription. In this regard, we focus on the lncRNAs in plants that have primarily been associated with controlling the chromatin environment of genes at the level of modifications, RNA POLYMERASE II (RNAPII) processivity and efficiency of transcription, and mediating the formation of transcriptionally activating and repressive chromatin loops. We discuss open questions in plant lncRNA epigenetic regulation and opportunities for future study of functionally significant lncRNAs with yet‐unknown epigenetic mechanisms.
Nonsuicidal self‐injury, sleep quality, and shame response to a laboratory stress task
Authors: Grove Jeremy L. , Carlson Steven E. , Parkhurst Kimberly A. , O'Neill John C. , Smith Timothy W. 
Published: October 2022

AbstractObjectiveNonsuicidal self‐injury (NSSI) frequently functions to regulate shame‐based emotions and cognitions in the context of interpersonal stress. The present study sought to examine how sleep quality (SQ) may influence this process in a laboratory setting.MethodsParticipants included 72 adults (Mage = 24.28; 36 with a lifetime history of NSSI) who completed a self‐report measure of prior month SQ and engaged in a modified Trier social stress task (TSST). State shame ratings were collected immediately before and following the TSST, as well as 5 min post‐TSST, to allow for the measurement of shame reactivity and recovery.ResultsNo significant results emerged for NSSI history and SQ as statistical predictors of shame reactivity. However, NSSI history was significantly associated with heightened shame intensity during the recovery period of the task, and this was moderated by SQ. Simple slopes analyses revealed a conditional effect whereby poorer SQ (1SD above the mean) was associated with greater intensity of shame during recovery, but only for those with a history of NSSI.ConclusionPoor SQ may contribute to worrisome emotional responses to daytime stressors in those at risk for NSSI.
Impaired Cardiometabolic Effects of Bromocriptine in Men With Early‐Onset Androgenic Alopecia
Authors: Krysiak Robert , Basiak Marcin , Szkróbka Witold , Okopień Bogusław 
Published: October 2022

AbstractBoth hyperprolactinemia and early‐onset androgenic alopecia are associated with increased cardiometabolic risk. The aim of this study was to assess whether early‐onset male‐pattern baldness modifies cardiometabolic effects of bromocriptine in men with prolactin excess. The study included 2 groups of men with prolactin excess: individuals with early‐onset androgenic alopecia (group 1) and individuals with normal hair growth (group 2). Both groups were matched for age, smoking habits, body mass index, blood pressure, and prolactin levels. Over the entire study period (4 months), all participants were treated with bromocriptine (7.5 mg daily). Plasma levels of hormones (prolactin, total testosterone, and bioavailable testosterone), glucose homeostasis markers, lipids, uric acid, high‐sensitivity C‐reactive protein (hsCRP), fibrinogen, homocysteine, and the urinary albumin‐to‐creatinine ratio (UACR) were measured at the beginning and at the end of the study period. The two groups differed in total testosterone, bioavailable testosterone, insulin sensitivity, high‐density lipoprotein (HDL) cholesterol, triglycerides, uric acid, hsCRP, fibrinogen, homocysteine, and UACR. In both groups, bromocriptine reduced prolactin, increased total and bioavailable testosterone, improved insulin sensitivity, and decreased uric acid, hsCRP, and homocysteine. The impact on prolactin, insulin sensitivity, uric acid, hsCRP, and homocysteine was stronger in group 2 than in group 1. Only in group 2 did the drug increase HDL cholesterol and decrease triglycerides, fibrinogen, and UACR. The impact on cardiometabolic risk factors correlated with a reduction in prolactin levels and an improvement in insulin sensitivity, and, in group 1, inversely correlated with testosterone levels. The obtained results suggest that men with early‐onset androgenic alopecia are partially resistant to the cardiometabolic effects of bromocriptine.
A prospective clinical study on the mechanisms underlying critical illness myopathy—A time‐course approach
Authors: Cacciani Nicola , Skärlén Åsa , Wen Ya , Zhang Xiang , Addinsall Alex B. , Llano‐Diez Monica , Li Meishan , Gransberg Lennart , Hedström Yvette , Bellander Bo‐Michael , Nelson David , Bergquist Jonas , Larsson Lars 
Published: October 2022

AbstractBackgroundCritical illness myopathy (CIM) is a consequence of modern critical care resulting in general muscle wasting and paralyses of all limb and trunk muscles, resulting in prolonged weaning from the ventilator, intensive care unit (ICU) treatment and rehabilitation. CIM is associated with severe morbidity/mortality and significant negative socioeconomic consequences, which has become increasingly evident during the current COVID‐19 pandemic, but underlying mechanisms remain elusive.MethodsTen neuro‐ICU patients exposed to long‐term controlled mechanical ventilation were followed with repeated muscle biopsies, electrophysiology and plasma collection three times per week for up to 12 days. Single muscle fibre contractile recordings were conducted on the first and final biopsy, and a multiomics approach was taken to analyse gene and protein expression in muscle and plasma at all collection time points.Results(i) A progressive preferential myosin loss, the hallmark of CIM, was observed in all neuro‐ICU patients during the observation period (myosin:actin ratio decreased from 2.0 in the first to 0.9 in the final biopsy, P < 0.001). The myosin loss was coupled to a general transcriptional downregulation of myofibrillar proteins (P < 0.05; absolute fold change >2) and activation of protein degradation pathways (false discovery rate [FDR] <0.1), resulting in significant muscle fibre atrophy and loss in force generation capacity, which declined >65% during the 12 day observation period (muscle fibre cross‐sectional area [CSA] and maximum single muscle fibre force normalized to CSA [specific force] declined 30% [P < 0.007] and 50% [P < 0.0001], respectively). (ii) Membrane excitability was not affected as indicated by the maintained compound muscle action potential amplitude upon supramaximal stimulation of upper and lower extremity motor nerves. (iii) Analyses of plasma revealed early activation of inflammatory and proinflammatory pathways (FDR < 0.1), as well as a redistribution of zinc ions from plasma.ConclusionsThe mechanical ventilation‐induced lung injury with release of cytokines/chemokines and the complete mechanical silencing uniquely observed in immobilized ICU patients affecting skeletal muscle gene/protein expression are forwarded as the dominant factors triggering CIM.
Post‐drainage stand growth and peat mineralization impair water quality from forested peatlands
Authors: Nieminen Mika , Hasselquist Eliza Maher , Mosquera Virginia , Ukonmaanaho Liisa , Sallantaus Tapani , Sarkkola Sakari 
Published: October 2022

AbstractMany recent studies have indicated upward trends in carbon and nutrient concentrations from drained peatland forests over time since their initial drainage, but the mechanisms behind these trends are still poorly understood. We gathered data on nitrogen and phosphorus concentrations discharged from 37 drained boreal peatland forests where we also had data on peat and tree stand characteristics. We found that tree stand volume and peat bulk density were positively correlated with the nitrogen and phosphorus concentrations discharged from particularly the deep‐peated sites. We interpret these results to indicate that a plausible reason for the reported upward trends in nutrient concentrations is the maturing and growing of the tree stands over time since initial drainage and the consequent increasing evapotranspiration capacity, which results in lowered soil water levels and enhanced aerobic peat mineralization. We discuss how our results should be considered in the management of drained peatland forests.
Enhancing the Soil Health–Watershed Health Nexus: Introduction
Authors: Fortuna Ann‐Marie , Lewandowski A. Marcelle , Osterholz William R. 
Published: October 2022

AbstractScientific concepts and measurements that relate soil and water resources are lacking in several areas, limiting our development of a framework or nexus to assess soil–watershed health. Current research designs rely on land management practices as a proxy for soil condition. Yet, conservation practices are often studied in isolation of each other, and adoption may be driven by state and federal farm programs that can incentivize a given management practice without accounting for current, novel farmer‐driven adoption of conservation systems. Despite the value of conservation management, its ability to predict soil health is often limited if based solely on land management because chemical, physical, and biological processes vary across time, discipline, and terrain. Similarly, connections between soil health and water quality are constrained due to several “grand challenges” that include dissimilar scales and the number of metrics required to correlate soil and water systems. Equally important is soil sampling within the critical flow path(s) that determines sediment/contaminant loading. In some instances, most of the sediment/contaminant loading during a portion or entire year results from channel and bank erosion and not overland flow that may not be within conservation management hectares. Additional challenges include legacy effects of prior land management, climate variability, and varying turnover rates of soil and water systems. This special section aims to frame research issues that inspire new approaches and collaborations for tackling the challenge of leveraging soil health to strengthen water management across plot, field, and watershed scales, using models, statistics, and other novel methodologies.