bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Security Challenges of Big Data Analytics: A Systematic Literature Review
Authors: Tilahun Tewodrose , Tsegaye Solomon 
Published: December 2022

The huge amount of data generated from heterogeneous sources such as social networking sites, healthcare applications, sensor networks and many other sources are drastically increasing from time to time swiftly. Big Data is described as extremely large datasets that have grown beyond the capability to manage and analyze them with traditional database processing tools. Big data analytics is the use of advanced analytical techniques against a very large heterogeneous datasets that include structured, semi-structured and unstructured data from different sources. The larger the quantity of data by itself is not advantageous unless analyzed to produce valuable information. This deluge amount of data creates an operational risk in which, the risks arise from storage devices, security of tools or the technologies used to analyze the data. In this paper, we perform a systematic literature review to give comprehensive review of security challenges and risks related to big data analytics. Security mechanisms such as cryptographic and non-cryptographic techniques are used to secure big data during analytics. The security of big data at rest and in transit gets enough investigation while a few researches had done at securing data at processing stage. Even though a number of possible techniques were proposed for big data security, it still suffers performance issues. This article is trying to explor security issues that used for preserving the Confidentiality, Integrity and Availability (CIA triad), non-repudiation as well as Access control in the context of big data analytics. Finally, we identify open future research directions for security of big data analytics. This paper also can serve as a good reference source for the development of modern security-preserving techniques to address various challenges of big data analytics security and privacy-issues.
Polygalacturonates of Biogenic Metals - Prospective Components of New Composite Preparations for Wheat
Authors: Aksylenko M. , Sheludko E. , Khimach N. , Yevdokymenko V. 
Published: December 2022

New bi- and polymetallic complexes of polygalacturonic acid with essential trace elements for pre-sowing treatment of winter wheat seeds were created.
Aims: The goal of the research was to create effective environmentally safe preparations of multifunctional action, with low cost rates for grain crops based on natural polymers of pectin nature and to determine the effectiveness of their use for pre-sowing treatment of winter wheat seeds.
Methodology: Methods of chemical synthesis of products, research of their structure by atomic force microscopy were used in the work. Laboratory and vegetative experiments were carried out. The substrate is quartz sand. Physiological and biochemical methods were used to determine the working absorbing surface of the roots and its absorbing activity, amylolytic activity, the content of photosynthesis pigments according to Wellburn. The results were processed using the methods of mathematical statistics.
Results: The atomic force microscopy method made it possible to detect a mixture of individual polymer molecules and their aggregates in pectin fractions. Depending on the concentration of pectins in the solution, they form different structures. New bi- and polymetallic complexes of polygalacturonic acid with essential trace elements for pre-sowing treatment of winter wheat seeds were created. According to the results of laboratory and vegetation experiments, the growth-stimulating activity of polygalacturonates of copper, iron, calcium, and nickel, which were used for pre-sowing processing of Smuhlyanka variety winter soft wheat seeds was determined. Preparations contribute to the active development of the root system of plants, strengthening their physiological activity. The investigated compounds are effective promising components of complex compositional preparations for modern agrotechnologies of winter wheat cultivation.
Conclusion: The use of such metal complexes at an insignificant rate of expenditure should contribute to the increase of economic and ecological indicators of crop production — the reduction of the cost price of wheat grain due to the increase in yield and grain quality.
Influence of Climate Resilient Technologies in Blackgram Productivity and Its Adoption in Low Rainfall Areas of Karaipottanar Sub Basin in Tiruchirapalli District in Tamil Nadu, India
Authors: Dhanushkodi V. , Krishnaveni A. , Sangeetha S. , Nageswari R. 
Published: December 2022

Climate change has emerged as one of the major global environmental issues that greatly influence agricultural production and food security. To meet these emerging challenges of climate change, there is an urgent need for developing promising improved technologies for mitigating of combating the adverse effect of climate change. Climate changes have a direct impact on rainfed crops including pulses. Reduction in yields due to climate change is prominent, since pulses occupy major area in rainfed situation. Hence the present investigation was carried out to study the impact of climate change on productivity of rainfed pulse and climate resilient technologies in increasing productivity of blackgram under rainfed situation. Mohanur block was purposively selected from Namakkal district of Tamil Nadu for the present study. Demonstrations were conducted in 50 farmer’s field in 3 villages, where climate resilient technologies viz., improved blackgram variety VBN 8, biofertilizer application, pulse wonder spray (@5kg/ha) and trap for reducing pest incidence were included under this study. In terms of yield, farmers received an average yield of 854 - 985kg/ha of blackgram variety VBN 8 against 734 kg/ha of old blackgram VBN 4 variety. The highest gross income of Rs.31200 - 39650/ha were also realized from blackgram followed by VBN 8. Highest benefit-cost ratio (2.9-3.0) was realized in case of blackgram variety VBN 8 compared to farmers practices with old variety (2.2-2.4). Based on the experiment it can be concluded that the cultivation of blackgram VBN 8 recorded more profit. Hence, new blackgram VBN 8 variety in rainfed condition is a viable option for combating negative impacts of climate change. The farmers expressed their preference (per cent) for blackgram variety VBN 8 on the aspects like less pest and disease resistance (83%), grain yield (78%), climate variation resistance (58%), time of maturity (76%), ease of processing during harvesting (89%), socio-cultural compatibility (74%) and market price (65%). Improved crop varieties are widely accepted as primary input for guaranteed increase in production and productivity under various situations
Internal Motivation to Enhance Compliance in a Hypertensive Patient: A Case Study
Authors: Thomas Kim, 
Published: December 2022

Aims: The incorporation of internal motivation questions into a care model can enhance compliance. This case study demonstrates how internal motivation and a single intervention strategy can effectively improve compliance in a hypertensive patient.
Study Design: A Case Study.
Place and Duration of Study: Office of RoundGlass Corporation, between April 2020-June 2020.
Methodology: 46-year old female with hypertension. Utilizing questions to determine internal motivation and create a complementary care plan she was able to maintain compliance and effectively reduce blood pressure readings through a daily walking program.
Results: Over the 2 -month period, patient was able to maintain daily compliance of walking a minimum of 20 minutes and reduce blood pressure readings from a start reading of 145/103 mmHg to 137/95 mmHg.
Conclusion: Identification of internal motivation is a valuable asset in enhancing compliance to a complementary care program for a hypertensive patient.
Living on the edge: Predicting invertebrate richness and rarity in disturbance‐prone aquatic–terrestrial ecosystems
Authors: Gething Kieran J. , Hayes Chloe , Webb Jonathan R. , Sykes Tim , England Judy , Stubbington Rachel 
Published: December 2022

Abstract
Temporal fluctuations in cause the spatial extent of wet and dry habitats to vary in aquatic–terrestrial riverine ecosystems, complicating their biomonitoring. As such, biomonitoring efforts may fail to characterize the species that inhabit such habitats, hampering assessments of their biodiversity and implementation of evidence‐informed management strategies.

Relationships between the dynamic characteristics of aquatic–terrestrial habitats and their communities are well known. Thus, habitat characteristics may enable estimation of faunal assemblage characteristics such as taxonomic richness, regardless of in‐channel water levels.

We investigated whether indicators summarizing habitat survey data can predict two metrics representing terrestrial invertebrate assemblages (e.g. taxa richness) in two aquatic–terrestrial habitats: exposed riverine sediments and dry temporary streams. We also compared the performance of unimetric and multimetric habitat indicators in making predictions.

In exposed riverine sediments, >88% of predictions were correlated with observed taxa richness and an index of conservation status. Values predicted by exposed riverine sediment samples were correlated with those observed in temporary stream channels with comparable riparian (i.e. largely agricultural) land use, but not those observed in channels with contrasting (i.e. more urban) land use.

Unimetric habitat indicators performed similarly to more complex multimetric indicators, with each explaining ≤6% of the variability in taxa richness and the index of conservation status. The different spatial scales at which invertebrates respond to habitat conditions and at which indicators record habitat conditions, and a more comprehensive training dataset that incorporates a full range of habitat conditions (i.e. land use), may improve future predictions.

We demonstrate that invertebrate assemblage characteristics can be predicted regardless of in‐channel water levels. Agreement between exposed riverine sediment predictions and temporary stream observations suggests that these predictions are transferable among a range of aquatic–terrestrial habitat types, and could thus be widely applied to aid conservation of riverine biodiversity in dynamic aquatic–terrestrial ecosystems.
Sophists, Roman Empire
Authors: Sánchez Hernández Juan Pablo 
Published: December 2022

AbstractPhilostratus coined the term “Second Sophistic” in hisLives of the sophiststo refer to a group of popular orators who lived roughly between 60 and 230ceand delighted the crowds with their speeches, combining spectacle, refined language, and historical erudition. But apart from being highly trained orators whose language was modelled after a canon of classical authors (mostly from the fifth to the fourth centuriesbce), sophists were also representatives of a burgeoning provincial elite and were considered so influential as moral and political arbiters that they were admitted into the administration of the Roman Empire.
Dual‐Sites Coordination Engineering of Single Atom Catalysts for Full‐Temperature Adaptive Flexible Ultralong‐Life Solid‐State Zn−Air Batteries
Authors: Gu Tengteng , Zhang Dantong , Yang Yan , Peng Chao , Xue Dongfeng , Zhi Chunyi , Zhu Min , Liu Jun 
Published: December 2022

AbstractHigh‐performance rechargeable Zn‐air batteries with long‐life stability are desirable for power applications in electric vehicles. The key component of the Zn‐air batteries is the bifunctional oxygen electrocatalyst, however, designing a bifunctional oxygen electrocatalyst with high intrinsic reversibility and durability is a challenge. Through density functional theory calculations, it is found that the catalytic activity originated from the electronic and geometric coordination structures synergistic effect of the Fe and Co dual‐sites with metal‐N4 coordination environment, assisting the stronger hybridization of electronic orbitals between Co (dxz, dz2) and OO* (px, pz), thus making the stronger O2 active ability of Co active site. These findings enable to development of a fancy dual single‐atom catalyst comprising adjacent FeN4 and CoN4 sites on N‐doped carbon matrix (FeCo‐NC). FeCo‐NC exhibits extraordinary bifunctional activities for oxygen reduction and evolution reaction (ORR/OER), which displays high half‐wave potential (0.893 V) for the ORR, and low overpotential (343 mV) at 10 mA cm−2 for the OER. The assembled FeCo‐NC air‐electrode works well in the flexible solid‐state Zn‐air battery with a high specific capacity of 747.0 mAh g−1, a long‐time stability of more than 400 h (30 °C), and also a superior performance at extreme temperatures (−30 °C–60 °C).
Multimorphic Materials: Spatially Tailoring Mechanical Properties via Selective Initiation of Interpenetrating Polymer Networks
Authors: Allen Marshall J. , Lien Hsu‐Ming , Prine Nathaniel , Burns Carter , Rylski Adrian K. , Gu Xiaodan , Cox Lewis M. , Mangolini Filippo , Freeman Benny D. , Page Zachariah A. 
Published: December 2022

AbstractAccess to multimaterial polymers with spatially localized properties and robust interfaces is anticipated to enable new capabilities in soft robotics, such as smooth actuation for advanced medical and manufacturing technologies. Here, orthogonal initiation is used to create interpenetrating polymer networks (IPNs) with spatial control over morphology and mechanical properties. Base catalyzes the formation of a stiff and strong polyurethane, while blue LEDs initiate the formation of a soft and elastic polyacrylate. IPN morphology is controlled by when the LED is turned “on”, with large phase separation occurring for short time delays (≈1–2 min) and a mixed morphology for longer time delays (>5 min), which is supported by dynamic mechanical analysis, small angle X‐ray scattering, and atomic force microscopy. Through tailoring morphology, tensile moduli and fracture toughness can be tuned across ≈1–2 orders of magnitude. Moreover, a simple spring model is used to explain the observed mechanical behavior. Photopatterning produces “multimorphic” materials, where morphology is spatially localized with fine precision (<100 µm), while maintaining a uniform chemical composition throughout to mitigate interfacial failure. As a final demonstration, the fabrication of hinges represents a possible use case for multimorphic materials in soft robotics.
Iodine‐modified Pt nanoparticles accelerate the hydrogenative ring‐opening of furfurals to linear alcohols
Authors: Zhang Likang , Li Xiang , Wang Jun , Zeng Zheling , Yang Weiran , Deng Shuguang , Deng Qiang 
Published: December 2022

AbstractThe hydrogenative ring‐opening of furfurals (furfural and 5‐methylfurfural) to linear diols (1,4‐pentanediol and 2,5‐hexanediol) is of great significance for bioderived fine chemical synthesis. Unfortunately, the catalytic activity and selectivity are unsatisfactory because of the interference of various side reactions, such as overhydrogenation to tetrahydrofurans. Herein, the preparation of an iodine (I) modified Pt‐based catalyst with abundant Pt‐I pairs is reported for the first time and shows high catalytic efficiency for linear diol synthesis with a yield of 80%–90% via the hydrogenative ring‐opening route, whereas bare Pt counterpart only shows tetrahydrofuran synthesis via the overhydrogenation route. The catalytic reaction mechanism shows the in‐situ hydrogen spillover‐promoted H−‐Pt‐I‐H+ pairs not only supply hydrogenation sites for the C=O hydrogenation step but also provide Brønsted acidic sites for the ring‐opening step. This work presents a feasible and convenient strategy for bifunctional catalysis with powerful linear diol synthesis over iodine‐modified noble metals.
Upper airway microbiome transplantation for patients with chronic rhinosinusitis
Authors: Mårtensson Anders , Cervin‐Hoberg Charlotte , Huygens Flavia , Lindstedt Malin , Sakellariou Christina , Greiff Lennart , Cervin Anders 
Published: December 2022

AbstractBackgroundChronic or recurrent rhinosinusitis without polyps (CRSsNP) is characterized by a persistent inflammation of the sinonasal mucosa. The underlying cause is unclear but increasing interest has been directed toward changes in the sinonasal microbiome as a potential driver.MethodsTwenty‐two patients diagnosed with CRSsNP were treated with antibiotics for 13 days, followed by 5 consecutive days of nasal microbiome transplants from healthy donors. Outcome measures were 22‐item Sino‐Nasal Outcome Test (SNOT‐22) questionnaire, total nasal symptom score (TNSS), endoscopic grading, 16S ribosomal RNA (rRNA) next generation sequencing (microbiome analysis), and nasal lavage fluid analysis of inflammatory cytokines. Patients were examined at the start of the study and after antibiotic treatment as well as 10 days and 3 months after the transplant series.ResultsAt the end of the study, patients reported significantly reduced SNOT‐22 scores and microbiome analysis showed significantly increased abundance and diversity. No significant change was observed for TNSS or endoscopic scoring.ConclusionNasal microbiome transplants obtained from healthy individuals and administered as nasal lavages to patients with CRSsNP are feasible. The patients reported significant and lasting reduction of symptoms and these findings were associated with a lasting increase in abundance and diversity of the local bacterial flora. The observations, which need to be confirmed by randomized controlled trials, may constitute a new treatment avenue for these difficult to treat patients where antibiotics only provide short lasting symptom control.
Therapeutic anti‐amyloid β antibodies cause neuronal disturbances
Authors: Adhikari Utpal Kumar , Khan Rizwan , Mikhael Meena , Balez Rachelle , David Monique Antoinette , Mahns David , Hardy John , Tayebi Mourad 
Published: December 2022

AbstractIntroductionRecent published clinical trial safety data showed that 41% of Alzheimer patients experienced amyloid‐related imaging abnormalities (ARIA), marks of microhemorrhages and edema in the brain, following administration of Biogen's Aduhelm/aducanumab (amino acids 3‐7 of the Aβ peptide). Similarly, Janssen/Pfizer's Bapineuzumab (amino acids 1‐5 of the Aβ peptide) and Roche's Gantenerumab (amino acids 2‐11/18‐27 of the Aβ peptide) also displayed ARIA in clinical trials, including microhemorrhage and focal areas of inflammation or vasogenic edema, respectively. The molecular mechanisms underlying ARIA caused by therapeutic anti‐Aβ antibodies remain largely unknown, however, recent reports demonstrated that therapeutic anti‐prion antibodies activate neuronal allergenic proteomes following cross‐linking cellular prion protein.MethodsHere, we report that treatment of human induced pluripotent stem cells‐ derived neurons (HSCN) from a non‐demented donor, co‐cultured with human primary microglia with anti‐Aβ1‐6, or anti‐Aβ17‐23 antibodies activate a significant number of allergenic‐related proteins as assessed by mass spectrometry.ResultsInterestingly, a large proportion of the identified proteins included cytokines such as interleukin (IL)‐4, IL‐12, and IL‐13 suggesting a type‐1 hypersensitivity response. Following flow cytometry analysis, several proinflammatory cytokines were significantly elevated following anti‐Aβ1‐6, or anti‐Aβ17‐23 antibody treatment.DiscussionThese results justify further and more robust investigation of the molecular mechanisms of ARIA during immunotherapy study trials of AD.HIGHLIGHTS
Allergenic‐related proteins are often linked with Alzheimer's disease (AD).
We investigated the effects of amyloid beta (Aβ) immunotherapy on stem cell derived neurons and primary neuronal cells co‐cultured with microglia.
Anti‐Aβ antibody treatment of neurons or neurons co‐cultured with microglia led to activation of a substantial number of allergenic‐related genes.
These allergenic‐related genes are associated with endothelial dysfunction possibly responsible for ARIA.
Tau‐PET is superior to phospho‐tau when predicting cognitive decline in symptomatic AD patients
Authors: Smith Ruben , Cullen Nicholas C. , Pichet Binette Alexa , Leuzy Antoine , Blennow Kaj , Zetterberg Henrik , Klein Gregory , Borroni Edilio , Ossenkoppele Rik , Janelidze Shorena , Palmqvist Sebastian , Mattsson‐Carlgren Niklas , Stomrud Erik , Hansson Oskar ,   for the Alzheimer's Disease Neuroimaging Initiative
Published: December 2022

AbstractIntroductionBiomarkers for the prediction of cognitive decline in patients with amnestic mild cognitive impairment (MCI) and amnestic mild dementia are needed for both clinical practice and clinical trials.MethodsWe evaluated the ability of tau‐PET (positron emission tomography), cortical atrophy on magnetic resonance imaging (MRI), baseline cognition, apolipoprotein E gene (APOE) status, plasma and cerebrospinal fluid (CSF) levels of phosphorylated tau‐217, neurofilament light (NfL), and amyloid beta (Aβ)42/40 ratio (individually and in combination) to predict cognitive decline over 2 years in BioFINDER‐2 and Alzheimer's Disease Neuroimaging Initiative (ADNI).ResultsBaseline tau‐PET and a composite baseline cognitive score were the strongest independent predictors of cognitive decline. Cortical thickness and NfL provided some additional information. Using a predictive algorithm to enrich patient selection in a theoretical clinical trial led to a significantly lower required sample size.DiscussionModels including baseline tau‐PET and cognition consistently provided the best prediction of change in cognitive function over 2 years in patients with amnestic MCI or mild dementia.
Magnetoelectric‐Field Electrodynamics: Search for Magnetoelectric Point Scatterers
Authors: Kamenetskii Eugene O. 
Published: December 2022

AbstractResonant scattering of electromagnetic (EM) waves by small particles is considered as one of the basic problems in metamaterial science. At present, special subwavelength resonators are considered as structural elements in chiral and bianisotropic metamaterials. There is a general consensus that these small scatterers behave like “artificial atoms” with strong electrical and magnetic responses and an interconnection between these responses. However, the observed effect of magnetoelectric (ME) coupling in these meta‐atoms is not associated with the near‐field manipulation properties caused by intrinsic magnetoelectricity. This arises the question whether ME point scatterers of EM radiation really exist. In this paper, we show that there are mesoscopic structures with electric and magnetic dipole‐carrying excitations that behave like point scatterers with their inherent magnetoelectricity. In such subwavelength resonators, coherent oscillations of the electric polarization and magnetization can be considered as quasistatic oscillations described by electrostatic (ES) and magnetostatic (MS) scalar wave functions. The ME resonance effect arises from the coupling of two, ES and MS, oscillations. The near fields of these resonators, called the ME near fields, are characterized by simultaneous violation of time reversal and inversion symmetry. In study of ME fields and EM problems associated with these fields, we put forward the concept of ME‐field electrodynamics.