bluuebunny/crossref_metadata_2025_split huggingface dataset:
Resting-state functional magnetic resonance imaging-based identification of altered brain the fractional amplitude of low frequency fluctuation in adolescent major depressive disorder patients undergoing electroconvulsive therapy
Authors: Wang Xing-Yu , Tan Huan , Li Xiao , Dai Lin-Qi , Zhang Zhi-Wei , Lv Fa-Jin , Yu Ren-Qiang 
Published: July 2022

PurposeWhile electroconvulsive therapy (ECT) has been repeatedly been shown to effectively and efficiently treat the major depressive disorder (MDD), the mechanistic basis for such therapeutic efficacy remains to be firmly established. As such, further research exploring the ECT-based treatment of MDD in an adolescent population is warranted.MethodsThis study included 30 treatment-naïve first-episode MDD patients and 30 healthy control (HC) individuals (aged 12–17 years). All participants were scanned using rs-fMRI, and the 30 MDD patients were scanned again after 2 weeks of the ECT treatment period. Intrinsic local activity in each voxel was assessed based on the fractional amplitude of low frequency fluctuation (fALFF) parameter, with all fALFF analyses being completed using the REST application. Correlations between ECT-related changes in fALFF and clinical parameters were additionally examined.ResultsRelative to HCs, MDD patients exhibited increased fALFF values in the right inferior frontal gyrus (ORBinf), inferior occipital gyrus (IOG), and the left middle frontal gyrus (MFG) at baseline. Following ECT, these patients exhibited significant increases in fALFF values in the right medial superior frontal gyrus (SFGmed), dorsolateral superior frontal gyrus (SFGdor), anterior cingulate, and paracingulate gyrus (ACG), median cingulate and paracingulate gyrus (DCG), and left MFG. MDD patient HAMD scores were negatively correlated with fALFF values when analyzing pre-ECT vs. post-HCT ΔHAMD and fALFF values in the right SFGmed, SFGdor, and the left MFG.ConclusionThese data suggest that ECT induced altered fALFF in some regions of the brain, suggesting that these alterations may serve as a neurobiological indicator of ECT effectiveness in MDD adolescents.
A bibliometric analysis of COVID-19 publications in neurology by using the visual mapping method
Authors: Zhang Qian , Li Jian , Weng Ling 
Published: July 2022

BackgroundThe characteristic symptom of coronavirus disease 2019 (COVID-19) is respiratory distress, but neurological symptoms are the most frequent extra-pulmonary symptoms. This study aims to explore the current status and hot topics of neurology-related research on COVID-19 using bibliometric analysis.MethodsPublications regarding neurology and COVID-19 were retrieved from the Web of Science Core Collection (WoSCC) on March 28 2022. The Advanced search was conducted using “TS = (‘COVID 19’ or ‘Novel Coronavirus 2019’ or ‘Coronavirus disease 2019’ or ‘2019-nCOV’ or ‘SARS-CoV-2’ or ‘coronavirus-2’) and TS = (‘neurology’or ‘neurological’ or ‘nervous system’ or ‘neurodegenerative disease’ or ‘brain’ or ‘cerebra’ or ‘nerve’)”. Microsoft Excel 2010 and VOSviewer were used to characterize the largest contributors, including the authors, journals, institutions, and countries. The hot topics and knowledge network were analyzed by CiteSpace and VOSviewer.ResultsA total of 5,329 publications between 2020 and 2022 were retrieved. The United States, Italy, and the United Kingdom were three key contributors to this field. Harvard Medical School, the Tehran University of Medical Sciences, and the UCL Queen Square Institute of Neurology were the major institutions with the largest publications. Josef Finsterer from the University of São Paulo (Austria) was the most prolific author. Tom Solomon from the University of Liverpool (UK) was the most cited author. Neurological Sciences and Frontiers in Neurology were the first two most productive journals, while Journal of Neurology held the first in terms of total citations and citations per publication. Cerebrovascular diseases, neurodegenerative diseases, encephalitis and encephalopathy, neuroimmune complications, neurological presentation in children, long COVID and mental health, and telemedicine were the central topics regarding the neurology-related research on COVID-19.ConclusionNeurology-related research on COVID-19 has attracted considerable attention worldwide. Research topics shifted from “morality, autopsy, and telemedicine” in 2020 to various COVID-19-related neurological symptoms in 2021, such as “stroke,” “Alzheimer's disease,” “Parkinson's disease,” “Guillain–Barre syndrome,” “multiple sclerosis,” “seizures in children,” and “long COVID.” “Applications of telemedicine in neurology during COVID-19 pandemic,” “COVID-19-related neurological complications and mechanism,” and “long COVID” require further study.
Perinatal outcomes among twin pregnancies with gestational diabetes mellitus: A nine-year retrospective cohort study
Authors: Lin Dongxin , Fan Dazhi , Li Pengsheng , Chen Gengdong , Rao Jiaming , Zhou Zixing , Zhang Huishan , Luo Xin , Ma Huiting , Feng Jingping , Lu Demei , Wang Lijuan , Lan Shiyan , Luo Caihong , Guo Xiaoling , Liu Zhengping 
Published: July 2022

ObjectiveTo compare the outcomes between gestational diabetes mellitus (GDM) vs. non-GDM twin gestations.MethodsA retrospective cohort study of 2,151 twin pregnancies was performed in a tertiary hospital in Foshan, China, 2012–2020. Pregnancy and neonatal outcomes were compared between women with vs. without GDM using 1:1 propensity score matching (PSM) and multivariable logistic models. For neonatal outcomes, generalized estimating equation (GEE) approach was used to address the intertwin correlation.ResultsOf the 2,151 participants, 472 women (21.9%) were diagnosed with GDM. Women with GDM were older and more likely to be overweight or obese, and more likely have chronic hypertension, assisted pregnancies and dichorionic twins. In the PSM cohort of 942 pregnancies, there was no statistical difference when comparing GDM twin pregnancies and non-GDM in any of the perinatal outcomes, especially in terms of preterm birth (PTB) &lt;37 weeks (P = 0.715), large for gestational age (LGA) (P = 0.521) and neonatal respiratory distress (NRDS) (P = 0.206). In the entire cohort, no significant adjusted ORs for these outcomes were obtained from logistic regression models adjusted for confounders (aOR for PTB &lt; 37 weeks: 1.25, 95% CI: 0.98–1.58; aOR for LGA: 1.26, 95% CI: 0.88–1.82; and aOR for NRDS, 1.05, 95% CI: 0.68–1.64).ConclusionTwin pregnancies with GDM and adequate prenatal care have comparable perinatal outcomes to those without.
“The worst thing that has happened to me”: Healthcare and social services professionals confronting death during the COVID-19 crisis
Authors: Hernández-Fernández Carlos , Meneses-Falcón Carmen 
Published: July 2022

ObjectivesThis study analyzes the subjective emotional impact COVID-19 deaths have had on healthcare, social services, and funeral services professionals, it explores the different implications, and analyzes the different reactions of health and social care professionals and funeral professionals to the volume of deaths.MethodsThis work is based on a qualitative, phenomenological, and interpretative approach through in-depth interviews with 42 informants, including 36 social and healthcare professionals, as well as 6 family members of those who died from COVID-19 in Madrid. The interviews were processed through a qualitative, interpretative, categorical analysis.ResultsHealthcare professionals were overexposed to a significant number of deaths under dramatic circumstances. Many of these professionals had difficulties processing their experiences and expressed the need for psychological help. The fact that certain professionals had previous exposure to high mortality rates was not a protective factor. Some coping differences were seen between healthcare professionals and professionals dedicated to the care of the deceased (undertakers or firemen), particularly in the degree to which they personalized the care they provided.ConclusionThe overexposure to death with the circumstances that existed during the state of emergency had a significant emotional impact on the professionals, which can lead to mental health problems in the near term.
Heart rhythm assessment in elite endurance athletes: A better method?
Authors: Ausland Ådne , Sandberg Edvard Liljedahl , Jortveit Jarle , Seiler Stephen 
Published: July 2022

IntroductionArrhythmias also occur among elite endurance athletes. Conventional diagnostic tools for assessment of arrhythmias suffer from limited availability and usability challenges, particularly under the demanding training conditions of an elite athlete. Among endurance athletes, there is a need for out-of-hospital monitoring to enhance detection of arrhythmias under conditions that are relevant and potentially provocative of underlying pathology. The Norwegian patch ECG247 Smart Heart Sensor has been developed to simplify the assessment of heart rhythm disorders. The current study aimed to evaluate the ECG247 Smart Heart Sensor function and usability in an elite athlete environment.MethodsA total of 13 professional cyclists from the UNO-X Pro Cycling Team were examined with the ECG247 Smart Heart Sensor during training camp in Spain, December 2021. All ECG data were analyzed by cardiologists at Sorlandet Hospital Arendal, Norway. The athletes also completed a brief questionnaire registering their training (from on-bike monitoring units) and provided self-assessment of usability parameters after the test.ResultsIn 8 of 13 athletes (69% male, age 23 ± 4 years), two test periods were performed with different ECG patches, resulting in a total of 21 tests with continuous ECG monitoring. Average total ECG test duration per athlete was 144 ± 47 h (89 ± 24 h/patch). Athletes performed an average of 15 ± 5 training h during each test. The ECG quality from all tests was considered satisfactory for rhythm analysis—also during exercise. The reported usability of the ECG247 Smart Heart Sensor was high, and no athletes reported trouble sleeping or training with the sensor. The automatic arrhythmia algorithm reported episodes of possible arrhythmias in 5 (24%) tests; 2 atrial flutter, 2 supraventricular tachycardia and 1 bradycardia (heart rate &lt;30/min). Manual assessment by physicians verified the episode of bradycardia but revealed normal sinus rhythm in all other tests. No false negative events were identified in over 1,800 h of ECG collection.ConclusionThe ECG247 Smart Heart Sensor allowed for high quality ECG monitoring with high usability during intensive exercise in athletes.
How effective is indocyanine green (ICG) in localization of malignant pulmonary nodules? A systematic review and meta-analysis
Authors: Gkikas Andreas , Lampridis Savvas , Patrini Davide , Kestenholz Peter B. , Scarci Marco , Minervini Fabrizio 
Published: July 2022

BackgroundVideo-Assisted and Robotic-Assisted techniques become constantly more prominent practice in thoracic surgery for lung cancer. Furthermore, the increased frequency in detection of small lung cancers makes the intra-operative identification of these cancers even more challenging. Indocyanine Green (ICG) is one of the most commonly used dyes that assists surgeons identify small lung cancers intra-operatively. Our study aimed to evaluate the effectiveness and safety of ICG in lung cancer detection.MethodsWe performed a systematic review of the literature by screening the databases of MEDLINE, EMBASE, CENTRAL and Scopus until 30th April 2022 and the first 300 articles of Google Scholar for any suitable grey literature. We included any study that investigated the effectiveness of ICG in lung cancer detection. We excluded studies that explored the use of ICG only in identification of intersegmental planes, lymph node mapping, case reports and non-English articles. We aimed to perform a meta-analysis on test accuracy studies using hierarchical summary receiver operating characteristic (HSROC) and the bivariate random-effects models. In cases where the data for a localization technique was not sufficient for that analysis, it was presented with tables with narrative purposes. Each study was assessed for Risk of Bias (RoB) and Applicability using the QUADAS-2 tool.ResultsWe found 30 eligible studies that included a total of 1,776 patients who underwent ICG localization of pulmonary nodules. We identified three ICG localization techniques: CT-guided, endobronchial and intravenous. From the 30 studies, 13 investigated CT-guided localization, 12 explored an endobronchial method while 8 studies administered ICG intravenously the median reported success rate was 94.3% (IQR: 91.4%–100%) and 98.3% (IQR: 94%–100%) for the first two techniques respectively. Intravenous ICG lung cancer localization showed Sensitivity of 88% (95% CI: 59%–0.97%) and Specificity of 25% (95% CI: 0.04%–0.74%). There were 15.2% (150/989) patients who experienced complications from CT guided ICG localization. No ICG-related complications were reported in endobronchial or intravenous techniques.ConclusionOur study provides a comprehensive review of the literature on ICG localization techniques for lung cancer. Current evidence suggests that ICG is boh effective and safe. Further prospective research with standardized protocols across multiple thoracic units is required in order to accurately validate these findings.
A Criterion of Colorectal Cancer Diagnosis Using Exosome Fluorescence-Lifetime Imaging
Authors: Borisov Alexey V. , Zakharova Olga A. , Samarinova Alisa A. , Yunusova Natalia V. , Cheremisina Olga V. , Kistenev Yury V. 
Published: July 2022

This study was aimed to investigate the applicability of the exosome fluorescence-lifetime imaging microscopy (FLIM) for colorectal cancer (CRC) diagnosis. Differential ultra-centrifugation was used to extract exosomes from the blood plasma of 11 patients with colon polyps (CPs) and 13 patients with CRC at the T2-4, N0-3, and M0-1 stages. Analysis was performed using a two-photon FLIM device. In total, 165 and 195 FLIM images were recorded for the CP and CCR patient groups, respectively. Two classes of exosomes differentiated by autofluorescence average lifetime tm were discovered in the samples. The first class of exosomes with tm = (0.21 ± 0.06) ns was mostly found in samples from CRC patients. The second class with tm = (0.43 ± 0.19) ns was mostly found in samples from CP patients. The relative number of “CRC-associated” exosomes Nch in the FLIM dataset was shown to be very small for the CP patient group and large for the CRC patient group. This difference was statistically significant. Therefore, the suggested CRS diagnostics criterion can be as follows. If Nch > 0.5, the probability of CRC is high. If Nch < 0.3, the probability of CRC is low.
Aspecto clínico, radiográfico, histopatológico e tratamento do Carcinoma de Seio Maxilar: Revisão de Literatura / Clinical, radiographic, histopathological aspect and treatment of Maxillary Sinus Carcinoma: Literature Review
Authors: Palma Flávio Augusto de Moraes , Amorim João Vitor Oliveira de , Góis Izabela Lima , Souza Victor Arthur Rodrigues de , Abreu Gustavo Baruc Andrade , Silva Felipe de Jesus , Siqueira Edllanckar dos Santos , Viana Amanda Guimarães , Martim Letícia , LimaTaga Márcio Luiz , Repeke Carlos Eduardo Palanch 
Published: July 2022

O carcinoma de seio maxilar é uma malignidade incomum, representando apenas 3% de todos os carcinomas de cabeça e pescoço. Contudo, entre os carcinomas dos seios paranasais, o seio maxilar é o sítio mais comum, correspondendo a 80% das lesões. O objetivo deste trabalho é identificar aspectos clínicos, radiográficos, histopatológico e tratamento da lesão. Trata-se de uma revisão da Literatura, através de uma pesquisa qualitativa, realizada por meio da pesquisa de artigos científicos em bases de dados Lilacs, Scielo, Medline e portais periódicos como BVS e PUBMED, utilizando as palavras-chaves: Carcinoma, Carcinoma de Células escamosas; Seio Maxilar, além de outras buscas através do google acadêmico, e buscas através de livros acadêmicos. A maioria das lesões permanece assintomática, e obtém leve predileção pelo gênero masculino. E para obter um diagnóstico, e importante conhecer o TNM (Classificação de Tumores Malignos), onde este sistema utiliza determinados critérios par obter o diagnóstico. Para um bom tratamento é recomendado a combinação de cirurgia e radioterapia pós-operatória é a melhor escolha, pois oferece melhor sobrevida que a radioterapia sozinha. Os carcinomas do seio maxilar consistem em apenas 3% de todos os carcinomas da cabeça e do pescoço, e costumam ser assintomáticas. Importante ressaltar a utilização do sistema TNM para obter o diagnóstico, além dos exames de imagem e histopatológico. A combinação de cirurgia e radioterapia pós-operatória é a melhor escolha, pois oferece melhor sobrevida que a radioterapia sozinha.
CONTRIBUIÇÃO DA ULTRASSONOGRAFIA NO DIAGNÓSTICO DA PLATINOSOMOSE FELINA
Authors: Silva Oliveira Bruna , Marques de Castro Ana Lígia , Da Silva Santos Jady Franciele , Ferreira Wagner Luis , Del Rio Pinoti5    Del Rio Pinoti Luciana 
Published: July 2022

RESUMO
A platinosomose é uma importante enfermidade hepatobiliar parasitária que acomete felinos, sendo eles de vida livre ou semi domiciliados. O agente etiológico é o trematódeo Platynosomum spp. E a doença é popularmente conhecida como “envenenamento por lagartixa”. As manifestações clínicas da platinosomose são inespecíficas assim como é incomum a observação de lesões hepáticas, o que dificulta o diagnóstico. Felinos possuem o hábito de caça e ao ingerir esses pequenos invertebrados, podem dar continuidade ao ciclo da platinosomose, uma vez que esses animais são os hospedeiros definitivos deste parasito. Esse trematódeo se aloja com frequência no trato biliar dos gatos, causando lesões e possível obstrução do ducto biliar. O grau de comprometimento das lesões hepáticas está na dependência tanto da imunidade, quanto da carga parasitária do animal. O diagnóstico de eleição é o exame parasitológico de fezes, embora ainda seja considerado pouco sensível, sendo relevante a utilização de outras ferramentas diagnósticas. O exame ultrassonográfico permite a observação de alterações hepáticas e até mesmo do próprio parasito no interior do ducto biliar, contribuindo para elucidação dessa enfermidade. Foi atendido no Hospital Veterinário “Luiz Quintiliano de Oliveira”, um felino com histórico de icterícia, e ao exame clínico observou-se escore corporal magro e desidratação em 8%. Após avaliação clínica do animal, o mesmo foi encaminhado para o setor de Diagnóstico por Imagem para avaliação ultrassonográfica abdominal, durante o exame visibilizou-se aumento das dimensões hepáticas, edema de parede em vesícula biliar e a presença pequena de estrutura filiforme, hiperecogênica, em seu interior.
Observation of quasi-elastic light scattering in BiFeO3
Authors: Oishi Eiichi , Fujii Yasuhiro , Koreeda Akitoshi , Satoh Takuya , Ito Toshimitsu 
Published: July 2022

Abstract
We observed quasi-elastic light scattering (QELS) in BiFeO3 using Raman spectroscopy over a temperature range of 300–860 K. The QELS has two componenets: narrow and broad ones. The temperature dependence of the intensity and linewidth of the broad component differed below and beyond the Néel point, and the broad QELS may have a magnetic origin.
Machine Learning model application and implementation in Project Management owner cost predictions using SAS
Authors: Atir Mohd 
Published: July 2022

<p>Use of Data science and machine learning algorithms in order to develop solutions for the management of various capital-intensive projects is explained through one of its applications in the estimation of project owner cost.</p>
<p>Owner cost prediction using machine learning techniques help in project cost allocation at the portfolio level. The application of ML algorithms using key factors like project size, project location, duration, extension, turned out to improve the accuracy of the cost estimation by 14%. The final Mean absolute percentage error of the model turned out to be 25.16%. </p>
<p>This research is a foundation for application in other areas of project management. It will also serve as a reference for application of machine learning models using historical data to predict the project owner cost for various capital-intensive projects.</p>
Information activity: phenomenon interpretation in the context of business
Authors: Baranetska Anna 
Published: July 2022

In the article the phenomenon of information activity in the context of the business sphere is analyzed. Information business is characterized as a multifunctional phenomenon. The concept of "information activity" from the stand point of its types and purposes is revealed. Different directions of information activity implementation in business are defined. The concept of information needs is interpreted. A unique algorithm for meeting the information needs of the company and the company is proposed. The information activity of the enterprise is understood as the satisfaction of its information requests for the implementation of its functioning, as well as a means of building internal organizational relationships. Information activities from the stand point of creating an appropriate information product and establishing relationships with various groups of the public, including consumers, are presented. Two groups of the public for business organizations (external and internal) are described. The concept of business information as a component of the business process is presented. Types of business information sources are represented, information resource practices are covered, as well as possible options for meeting information needs. The importance of the concept of creating e-government — e-Government — as an important modern information resource is pointed out. Two levels of information flows in business companies are identified. The media and, inparticular, corporate media are described as a powerful channel for information activities in the direction of communication with consumers. Endogenous and exogenous vectors of satisfaction of information needs of business structures are revealed, the process of realization of information inquiries of the company is presented as dichotomous.
Pengaruh Kesadaran Wajib Pajak, Pelayanan Perpajakan Dan Kepatuhan Wajib Pajak UMKM Terhadap Penerimaan Pajak Pada Kantor Pelayanan Pajak Pratama Pematangsiantar
Authors: Ayu Gustia Laras , Sriwiyanti Eva , Damanik Elfina OP 
Published: July 2022

Penelitian ini bertujuan untuk mengetahui pengaruh dari kesadaran wajib pajak, pelayanan perpajakan, dan kepatuhan wajib pajak UMKM. Sedangkan kesadaran wajib pajak, pelayanan perpajakan, dan kepatuhan kewajiban moral relevan dengan Teori atribusi. Penelitian ini merupakan penelitian kuantitatif yang dikualitatifkan dengan jumlah responden 100 UMKM yang terdaftar Pada Kantor Pelayanan Pajak Pratama Pematangsiantar. Teknik pengambilan sampel menggunakan rumus slovin dan pengumpulan sampel yang digunakan adalah random sampling. Data yang digunakan adalah data primer dengan menggunakan kuesioner yang disebarkan melalui google form, dan mendatangi langsung pelaku UMKM yang dalam hal ini sebagai responden penelitian. Hasil penyebaran kuesioner dikumpulkan terlebih dahulu, setelah itu dioalah dengan memanfaatkan IMB SPSS versi 25. Hasil penelitian ini menunjukkan kesadaran wajib pajak, pelayanan, dan kewajiban moral berpengaruh positif dan signifikan terhadap penerimaan pajak pada Kantor Pelayanan Pajak Pratama Pematangsiantar