bluuebunny/crossref_metadata_2025_split huggingface dataset:
The health and wellbeing of Australian social housing tenants compared to people living in other types of housing
Authors: Freund Megan , Clapham Matt , Ooi Jia Ying , Adamson David , Boyes Allison , Sanson-Fisher Robert 
Published: November 2022

Abstract
Background
Although social housing provides access to safe and affordable housing, recent studies have found that social housing tenants consistently have lower levels of health and well-being compared to other people. Given this, there is a need to examine multimorbidity for social housing tenants.
Methods
Secondary data analysis of the 2017-18 Australian National Health Survey (n = 14,327) compared the health of adults residing in social housing compared to people in other housing types (private rentals, homeowners, and homeowners/mortgagees).
Results
Most health factors examined were more prevalent in social housing tenants compared to those living in other housing types. Individual health problems identified as more highly prevalent in social housing tenants compared to all other housing types included mental health issues (43%), arthritis (36%), back problems (32%), hypertension (25%), asthma (22%) and COPD (11%). Twenty-four percent of social housing tenants reported five or more health factors compared to 3–6% of people in other housing types.
Conclusions
Although these findings are not unexpected, they provide more detailed evidence that social housing providers and policy makers should consider when planning future initiatives.
Vertical subluxation caused by infection around the odontoid process: a case report
Authors: Sanada Kyoichi , Tanaka Jun , Shiokawa Teruaki , Shibata Tatsuya , Hagihara Shusuke , Yamamoto Takuaki 
Published: November 2022

Abstract
Background: There are few reports of cases with vertical subluxation. We report our experience of a vertical subluxation of the atlantoaxial joint caused by infection.
Case presentation: A 63-year-old man had a 5-month history of neck pain. He was treated for rheumatoid arthritis by a local doctor. At admission to our hospital, he had neck pain and complained of dysphagia and hoarseness. His white blood cell count and C-reactive protein were 7200/mm3 and 4.86 mg/dL. Cervical X-ray showed atlantoaxial subluxation. Computed tomography showed osteolysis around the odontoid process, including the atlantooccipital and atlantoaxial joints, causing vertical subluxation. Magnetic resonance imaging showed spinal cord and brainstem compression and the presence of fluid. Gadolinium-enhanced magnetic resonance imaging showed enhancement around the odontoid process. We performed occipital-cervical spine fixation and C1 laminectomy. Following surgery, his symptoms completely resolved. Bone fusion was confirmed 6 months after surgery.
Conclusion: If subluxation of the upper cervical spine occurs rapidly, infection should be considered.
Unraveling transcriptomics of sorghum grain carotenoids: A step forward for biofortification
Authors: Cruet-Burgos Clara , Rhodes Davina H. 
Published: November 2022

Abstract
Background
Sorghum (Sorghum bicolor [L.] Moench) is a promising target for pro-vitamin A biofortification as it is a global staple crop, particularly in regions where vitamin A deficiency is prevalent. As with most cereal grains, carotenoid concentrations are low in sorghum, and breeding could be a feasible strategy to increase pro-vitamin A carotenoids to biologically relevant concentrations. However, there are knowledge gaps in the biosynthesis and regulation of sorghum grain carotenoids, which can limit breeding effectiveness. The aim of this research was to gain an understanding of the transcriptional regulation of a priori candidate genes in carotenoid precursor, biosynthesis, and degradation pathways.
Results
We used RNA sequencing of grain to compare the transcriptional profile of four sorghum accessions with contrasting carotenoid profiles through grain development. Most a priori candidate genes involved in the precursor MEP, carotenoid biosynthesis, and carotenoid degradation pathways were found to be differentially expressed between sorghum grain developmental stages. There was also differential expression of some of the a priori candidate genes between high and low carotenoid content groups at each developmental time point. Among these, we propose geranyl geranyl pyrophosphate synthase (GGPPS), phytoene synthase (PSY), and phytoene desaturase (PDS) as promising targets for pro-vitamin A carotenoid biofortification efforts in sorghum grain.
Conclusions
A deeper understanding of the controls underlying biosynthesis and degradation of sorghum grain carotenoids is needed to advance biofortification efforts. This study provides the first insights into the regulation of sorghum grain carotenoid biosynthesis and degradation, suggesting potential gene targets to prioritize for molecular breeding.
Benefits associated with topoclimatic zoning for native species of the Brazilian Amazon: methodological innovation
Authors: Martorano Lucieta Guerreiro , Júnior Silvio Brienza , Lisboa Leila Sheila Silva , de Moraes José Reinaldo da Silva Cabral 
Published: November 2022

Abstract

In 2006 the soybean moratorium provided the impulse for the installation of a large grain exporting port in western Pará, and the states of Mato Grosso and Pará became references at a national level for grain production. Topoclimatological zoning for species is a methodological innovation that accounts for phenological phases based on herbarium registries, and occurrence as described by RADAMBRAZIL forest inventories. This process also includes climatic data including range of annual precipitation, quarterly maximum and minimum rainfall, months with total rainfall below 60 mm, ranges of water stress with soil water holding capacity based on 300 mm, maximum, minimum, and average thermal regimes, air humidity and vapor pressure deficit, and altitude ranges. The zoning process is finalized by a panel of specialists who assign importance values to each variable and conduct statistical analyses to define the variables that best explain the productive potential for each species. This study presents the results of topoclimatological zoning for the species paricá (Schizolobium amazonicum) and tachi-branco (Tachigali vulgarisL.F.). Through this method, it is possible to identify areas with high, medium, and low topo climatic potential for any native species in the Amazon.
Validation and reliability of a therapeutic adherence measurement scale
Authors: Sánchez José Ángel González , Cerro Enrique Pacheco del , Sorinano Ismael Ortuño , Jiménez Daniel Muñoz , Iglesias María José Hurtado , Palacio Encarnación Fernández del 
Published: November 2022

Abstract
Introduction-Objectives: the different studies have shown the lack of a universal measurement system or gold standard, for which a scale has been developed using the most representative theoretical and empirical models, the objective is to validate the scale and verify the factors that influence. Methodology: a validation study is carried out through a cross-sectional descriptive observational study of nursing consultations, of chronic patients, located in a hospital. Results: a reliability of 0.846 is obtained from the scale under study, with an interclass correlation of 0.149. The scale is modified with nine items, obtaining a reliability of 0.750, and with an intraclass correlation of 0.835. There is a good correlation between the socioeconomic data and the characteristics of the dwelling. In regression models, these data (socioeconomic and housing) seem to have the highest incidence. Discussion: The data, as in other studies, confirm the values ​​of risk factors, or that affect adherence values, emphasizing socioeconomic and housing data. The modified scale presents acceptable reliability data. Conclusions: The scale can be used to measure adherence to patients with chronic diseases, it would be useful to increase the number of patients under study and achieve representativeness in each chronic disease.
Ambient Nitrogen Dioxide and Cardiovascular Diseases in Rural Regions: A Time-series Analyses Using Data From the New Rural Cooperative Medical Scheme in Fuyang, East China
Authors: Dong Teng-fei , Zha Zhen-qiu , Sun Liang , Liu Ling-li , Li Xing-yang , Wang Yuan , Meng Xiang-long , Li Huai-biao , Wang Hong-li , Nie Huan-huan , Yang Lin-Sheng 
Published: November 2022

Abstract
Background
Most of studies relating ambient cardiovascular hospital admissions exposure to hospital admissions for cardiovascular diseases (CVDs) were conducted among urban population. Whether and to what extent these results could be generalizable to rural population remains unknown. We addressed this question using data from the New Rural Cooperative Medical Scheme (NRCMS) in Fuyang, Anhui, China.
Methods
Daily hospital admissions for total CVDs, ischaemic heart disease, heart failure, heart rhythm disturbances, ischaemic stroke, and hemorrhagic stroke in rural regions of Fuyang, China were extracted from NRCMS between January 2015 and June 2017. A two-stage time-series analysis method was used to assess the associations between NO2 and CVD hospital admissions and the disease burden fractions attributable to NO2.
Results
In our study period, the average number (standard deviation) of hospital admissions per day were 488.2 (117.1) for total CVDs, 179.8 (45.6) for ischaemic heart disease, 7.0 (3.3) for heart rhythm disturbances, 13.2 (7.2) for heart failure, 267.9 (67.7) for ischaemic stroke, and 20.2 (6.4) for hemorrhagic stroke. The 10 µg/m3 increase of NO2 was related to an elevated risk of 1.9% (RR: 1.019, 95% CI: 1.005 to 1.032) for hospital admissions of total CVDs at lag0-2 day, 2.1% (1.021, 1.006 to 1.036) for ischaemic heart disease, and 2.1% (1.021, 1.006 to 1.035) for ischaemic stroke, respectively. While no significant association was observed between NO2 and hospital admissions for heart rhythm disturbances, heart failure, and hemorrhagic stroke. The attributable fractions of total CVDs, ischaemic heart disease, and ischaemic stroke to NO2 were 6.52% (1.87–10.94%), 7.31% (2.19–12.17%) and 7.12% (2.14–11.85%), respectively.
Conclusions
Our findings suggest that CVD burdens in rural population are also partly attributed to short-term exposure to NO2. More studies across rural regions are required to replicate our findings.
Benefits of physical activity on reproductive health functions among polycystic ovarian syndrome women: A systematic review
Authors: Butt Muhammad Salman , Saleem Javeria , Zakar Rubeena , Aiman Sobia , Khan Muhammad Zeeshan , Fischer Florian 
Published: November 2022

Abstract
Background
Polycystic ovary syndrome (PCOS) is amongst the predominant endocrine disorders of reproductive-aged women. The prevalence of PCOS has been estimated at around 6–26%, affecting 105 million worldwide. This systematic review aimed to synthesize the evidence on the effects of physical activity on reproductive health functions among PCOS women.
Methods
The systematic review includes randomization-controlled trials (RCTs) on physical exercise and reproductive functions among women with PCOS. Studies in English language published between January 2010 and December 2020 were identified via PubMed. A combination of medical subject headings terms of physical activity, exercise, menstrual cycle, hyperandrogenism, reproductive hormone, hirsutism, and PCOS were used.
Results
Overall, six RCTs were included in this systematic review. The studies investigated interventions of physical activity of any intensity and volume and measured reproductive functions, hormonal and menstrual improvement. The inclusion of physical activity alone or in a combination with other therapeutic interventions improved the reproductive outcomes.
Conclusion
The reproductive functions of PCOS women can be improved with physical activity. Furthermore, physical activity can also reduce infertility, as well as social and psychological stress among women.
PROSPERO Systematic review registration:
CRD42020213732
Association between sociodemographic determinants and health behaviors, and clustering of health risk behaviors among 28,047 adults: A cross-sectional study among adults from the general Norwegian population
Authors: Korslund Silje B. , Hansen Bjørge H. , Bjørkkjær Tormod 
Published: November 2022

Abstract
Background
Understanding the associations between health behaviors and which subgroups are at risk of developing health risk behaviors is vital knowledge to develop effective public health interventions to reduce the high prevalence of non-communicable diseases (NCDs). The objective of the study was to assess the association between physical activity, diet, tobacco use, and alcohol consumption and sociodemographic determinants (sex and education), and to examine clustering patterns of these health behaviors.
Method
Data was collected from an online self-reported questionnaire from the Norwegian public health survey conducted in 2019. The study sample consisted of 28,047 adults (≥ 18 years old) from Agder county in Southern Norway. Chi-square tests and logistic regression analysis were used to determine the association between sex and education according to physical activity, diet, tobacco use and alcohol consumption. Linear regression was used to examine the association between educational level and number of health risk behaviors, and cluster analysis were performed to determine cluster patterns.
Results
Females were more likely than men to meet the national public health recommendations for diet (p < 0.001), tobacco use (p < 0.01), and alcohol consumption (p < 0.001). High education was associated with meeting the recommendations for each of the four health behaviors and with a lower risk of having three or four health risk behaviors simultaneously. Furthermore, clustering of health risk behaviors was observed in five of the sixteen health behavior patterns.
Conclusion
Our findings show a higher risk of having multiple health risk behaviors for males and individuals with low education. These subgroups should be targeted in future public health interventions. Clustering patterns were observed in over 30% of the health behavior patterns. More research is needed on the causal relationship between health behaviors and socioeconomic factors, and the association between clustering and health outcomes to design effective interventions in the future.
Zinc Status in Public Health: Exploring Emerging Research Trends Through Bibliometric Analysis of the Historical Context from 1978 to 2022
Authors: Mohamad Nur Syamimi , Tan Ling Ling , Ali Nurul Izzati Mohd , Mazlan Nur-Fadhilah , Sage Edison Eukun , Hassan Nurul Izzaty , Goh Choo Ta 
Published: November 2022

Abstract
The current study aims to provide a roadmap for future research by analyzing the research structures and trends in scholarly publications related to the status of zinc in public health. Only journal articles published between 1978 and 2022 are included in the refined bibliographical outputs retrieved from the Web of Science (WoS) database. The first section announces findings based on WoS categories, such as discipline heterogeneity, times cited and publications over time, and citation reports. The second section then employs VoSViewer software for bibliometric analysis, which includes a thorough examination of co-authorship among researchers, organizations, and countries and a count of all bibliographic databases among documents. The final section discusses the research's weaknesses and strengths in zinc status, public health, and potential future directions. 7158 authors contributed to 1730 papers (including 339 with publications, more than three times). "Keen, C.L." is a researcher with the most publications and a better understanding of zinc status in public health. Meanwhile, the United States has been the epicenter of research on the status of zinc in public health due to the highest percentage of publications with the most citations and collaboration with the rest of the world, with the top institution being the University of California, Davis. Future research can be organized collaboratively based on hot topics from co-occurrence network mapping and bibliographic couplings to improve zinc status and protect public health.
Re: “Dealing With The Problem Of Planning Construction Site Layout Based On Quadratic Assignment Problem Method, Using Ant-Lion hybrid algorithm.
Authors: Son Pham Vu Hong , Lam To Dieu 
Published: November 2022

Abstract

Construction site layout planning (CSLP) problem is important in construction management. Facilities have conflicting purposes in the available space on the construction site, increasing the inefficient transportation of facilities. This is the main cause leading to the loss of operational productivity and increasing project construction costs. Therefore, the facilities planning and layout to be established in the appropriate locations to find an optimal solution in the available space is a problem to be solved using quadratic assignment problems (QAP) method. In the past, there were several ways to solve the QAP problem using metaheuristic methods such as genetic algorithm (GA),mixed integer programming (M.I.P), and artificial bee colony. However, each method has both advantages and disadvantages. Therefore, this study proposes a new algorithm that combines mutation, crossover, tournament selection (TS), and opposition-based learning with improved ant lion optimization based on ant lion optimizer (ALO) to solve the QAP problem of optimizing facilities layout on the construction site to find the most optimal results in the shortest time. The comparison results in the research paper belowhave shown that the new, improved hybrid algorithm outperformed previous algorithms such as the GA, MIP, and original ALO algorithm.
Assessment of plasmids for relating the 2020 Salmonella enterica serovar Newport onion outbreak to farms implicated by the outbreak investigation
Authors: Commichaux Seth , Rand Hugh , Javkar Kiran , Molloy Erin K. , Pettengill James B. , Pightling Arthur , Hoffmann Maria , Pop Mihai , Jayeola Victor , Foley Steven , Luo Yan 
Published: November 2022

Abstract
Background
The Salmonella enterica serovar Newport red onion outbreak of 2020 was the largest foodborne outbreak of Salmonella in over a decade. The epidemiological investigation suggested two farms as the likely source of contamination. However, single nucleotide polymorphism (SNP) analysis of the whole genome sequencing data did not find any Salmonella isolates from the farm regions that were closely related to the clinical isolates—preventing the use of phylogenetics in source identification. Here, we explored an alternative method for analyzing the whole genome sequencing data driven by the hypothesis that if the outbreak strain had come from the farm regions, then the clinical isolates would disproportionately contain plasmids found in isolates from the farm regions due to recent horizontal transfer.
Results
SNP analysis confirmed that the clinical isolates formed a highly related clade with evidence for ancestry in California going back a decade. The clinical isolates not only had a large and highly conserved core genome (4,399 genes), but also 2,577 sparsely distributed accessory genes—at least 64% of which were carried on plasmids. Amongst the clinical isolates and Salmonella isolates from the farm regions were 2,187 and 503 putative plasmids, respectively. High similarity was observed between 17 plasmids from 8 farm isolates and 14 plasmids from 13 clinical isolates. Phylogenetic analysis suggested the highly similar plasmids shared a recent common ancestor and might have been transferred via intermediary species, but the seeming promiscuity of the plasmids prevented any conclusions about geographic location, isolation source, and time since transfer. Our sampling analysis suggested that observing a similar number and combination of highly similar plasmids in random samples of environmental Salmonella enterica within NCBI Pathogen Detection database was unlikely, supporting a connection between the outbreak strain and the farms implicated by the epidemiological investigation.
Conclusion
Horizontally transferred plasmids provided evidence for a connection between clinical isolates and the farms implicated as the source of the outbreak. Our case study suggests that such analyses might add a new dimension to source tracking investigations, but highlights the need for detailed and accurate metadata, more extensive environmental sampling, and a better understanding of plasmid molecular evolution.
Sample Size Calculations for Indirect Standardization
Authors: Wang Yifei , Chu Philip 
Published: November 2022

Abstract
Indirect standardization, and its associated parameter the Standardized Incidence Ratio, is a commonly-used tool in hospital profiling for comparing the incidence of negative outcomes between an index hospital and a larger population of reference hospitals, while adjusting for confounding factors. For hypothesis testing and statistical inference, the denominator of the Standardized Incidence Ratio, whose computation requires the distribution of confounding covariates in the index hospital, is assumed to be known, and is thus fixed. This assumption severely compromises one's ability to compute required sample sizes for high-powered indirect standardization, as in the contexts where sample size calculation is desired, it's difficult to even estimate such a covariate distribution, much less know it outright. This paper presents novel statistical methodology to perform hypothesis testing and sample size calculation for the Standardized Incidence Ratio while not knowing the covariate distribution of the index hospital, accounting for the mathematical uncertainty this lack of knowledge induces. We apply our methods to example data, as well as to simulation studies, to assess both its capabilities in a vacuum and in comparison to traditional methods of indirect standardization.
Investigation of the effective atomic number dependency on energy using collision stopping powers for charged particles applied in radiotherapy
Authors: Rezaeian Peiman , Kashian Sedigheh , Mehrara Rojin 
Published: November 2022

Abstract

As an important component in medical applications, dosimetry, and radiotherapy studies, the effective atomic number of body tissue, tissue equivalent substances, and dosimetry compounds are investigated. In this research, considering the Coulombic interaction of charged particles, using the collision stopping power and the NIST library data, the effective atomic number of various materials at different energies is calculated for common radiotherapy particles such as an electron, proton, alpha, and carbon ions. Taking into account the direct calculation method based on the collision stopping power, the effective atomic number for electron, proton, alpha, and carbon particles is determined for a group of dosimetry and tissue equivalent materials. Results of the calculations based on the collision stopping power showed that the values of the effective atomic number are equal to the total number of electrons in each molecule of the compound, which is quite justified by the physics of Bethe's formulas.