bluuebunny/crossref_metadata_2025_split huggingface dataset:
Activate Your Health: impact of a real-life programme promoting healthy lifestyle habits in Canadian workers
Authors: Kugathasan Thiffya Arabi , Gilbert Jo-Anne , Laberge Suzanne , Tremblay Jonathan , Mathieu Marie-Eve 
Published: March 2022

SummaryThe workplace has been suggested as a good setting for the promotion of healthy lifestyles. This article examines the impact of Activate Your Health programme, provided over an average of 1.35 years, on employee health and lifestyle habits (actual and intention to improve). Companies selected one of the programme’s four options (number of interventions in parentheses): Control (2), Light (8), Moderate (13) and High (14). Employees (n = 524) completed an online questionnaire at baseline and post-intervention. Mixed-effect models and generalized estimating equations models were used, where appropriate. There was an interaction effect of time by option for the number of employees intending to improve sleep habits (p = 0.030): +11.0% in Light (p = 0.013). No significant interaction effect of time by option was observed for body weight, body mass index, number of health problems or lifestyle habits (actual and intention to improve). When stratified by sex, there was an interaction effect of time by option for the number of women intending to improve sleep habits (p = 0.023): −26.1% in Moderate (p = 0.014). There was an interaction effect of time by option for body weight in men (p = 0.001): −0.58 kg in High (p = 0.031) and +2.58 kg in Control (p = 0.005). Other outcomes of interest were stable or improved post-intervention, regardless of option. The Activate Your Health programme allowed employees to maintain or improve outcomes related to health and lifestyle habits. A package like High may be beneficial for body weight regulation in men.
Western Baltic cod in distress: decline in energy reserves since 1977
Authors: Receveur Aurore , Bleil Martina , Funk Steffen , Stötera Sven , Gräwe Ulf , Naumann Michael , Dutheil Cyril , Krumme Uwe 
Published: March 2022

Abstract
The western Baltic Sea cod (WBC) stock is at historically low levels, mainly attributed to high fishing pressure and low recruitment. Stable stock assessment metrics suggested recovery potential, given appropriate fisheries management measures. However, changing environmental conditions violate stability assumptions, may negatively affect WBC, and challenge the resource management. The present study explored 42 years of changes in WBC biological parameters. WBC body condition gradually decreased over the last decades for juveniles and adults, with a rapid decrease in recent years when a single cohort dominated the overfished stock. The hepato-somatic index and the muscle weight decreased by 50% and 10% in the last 10 years, respectively, suggesting severely decreasing energy reserves and productivity. The changes in energy reserves were associated with changes in environmental conditions (increase in bottom water temperature, expansion of hypoxic areas during late summer/autumn), and changes in diet composition (less herring). A key bottleneck is the warming and longer-lasting summer period when WBC, trapped between warmed shallow waters and hypoxic deeper waters, have to mobilize energy reserves to account for reduced feeding opportunities and thermal stress. Our results suggest that stock recovery is unlikely to happen by fisheries management alone if environmental trajectories remain unchanged.
Frameless—finding and refining a sampling frame for surveying recreational fisheries: lessons from estimating Swedish harvest of western Baltic cod
Authors: Sande Hege , Prista Nuno , de Groote Annica , Casini Michele , Jones Cynthia , Sundelöf Andreas 
Published: March 2022

Abstract
To achieve sustainable fisheries, advice to management should be based on reliable science and unbiased data. Attaining quality data (i.e. precise and unbiased) on recreational fishing can be challenging, particularly when prior knowledge of the sector is limited and a proper sample frame of recreational fishers or vessels does not exist. In this study, a registry of access points was constructed for the Swedish south–west coast and used as a spatial sample frame in determining both effort and catches of the private boat fishery. Sampling dates, times for sampling, and access points visited were selected using probabilistic methods, ensuring unbiased results. The final multi-stage sampling design involved multiple strata, clusters, and probability selection methods and enabled first-time estimation of Swedish recreational landings of western Baltic cod by private boats to be used in stock assessment. Concurrent data collection covering aspects such as boat counts at access points, provided additional information on e.g. activity patterns. That additional information opens possibilities to refine the design of the original survey and optimize the sampling effort towards different goals, such as other fished resources. In this paper, we reflect on the challenges that limitations in initial information poses to the design and deployment of a new recreational fisheries survey. We suggest ways, whereby indirect sampling frames can be developed from initially incomplete or limited information to access the fishers and their catch. Our experience shows that, despite initial frame and knowledge limitations, full probabilistic methods are worth considering in data limited scenarios and that the design-based point estimates and variances they provide on recreational fishing effort and catches are useful in guiding initial management and the next steps of survey improvement.
Cefiderocol: EUCAST criteria for disc diffusion and broth microdilution for antimicrobial susceptibility testing
Authors: Matuschek Erika , Longshaw Christopher , Takemura Miki , Yamano Yoshinori , Kahlmeter Gunnar 
Published: March 2022

Abstract

Objectives
The reproducibility of cefiderocol MIC determination using broth microdilution (BMD) in iron-depleted CAMHB (ID-CAMHB) was investigated, and the EUCAST disc diffusion (DD) method for cefiderocol susceptibility testing was developed and validated against reference BMD.

Methods
Cefiderocol values were determined for wild-type (WT) and non-WT isolates using BMD plates with ID-CAMHB (Thermo Scientific, Oakwood, USA) per EUCAST guidelines. DD was performed using standard EUCAST methodology on unsupplemented Mueller–Hinton agar with cefiderocol 30 μg discs. Control agents were included in all tests. MICs were correlated with zone diameters (ZD), and ZD breakpoints (BP) best corresponding to the MIC BPs were determined. Areas of technical uncertainty (ATU) were included where appropriate. External laboratory validation of cefiderocol DD was performed per the EUCAST SOP 9.2.

Results
MIC and ZD distributions for cefiderocol against WT isolates were established. Cefiderocol ZD BPs were set at susceptible ≥22 mm, resistant &lt;22 mm for Enterobacterales and Pseudomonas aeruginosa and ATUs were decided. For Acinetobacter baumannii and Stenotrophomonas maltophilia, ZD cut-off values of ≥17 mm and ≥20 mm corresponded to MIC values of ≤2 and ≤0.5 mg/L, respectively. Cefiderocol ZDs for Escherichia coli ATCC 25922 (target 27 mm) and P. aeruginosa ATCC 27853 (target 26 mm) were within ±3 mm of the target values. For DD, there was no problematic variation between discs, media or laboratories.

Conclusions
DD is a robust and easy-to-perform method for cefiderocol susceptibility testing. For isolates with results in the ATU, an MIC test should be performed to confirm the results.
From OIE standards to responsible and prudent use of antimicrobials: supporting stewardship for the use of antimicrobial agents in animals
Authors: Pinto Ferreira Jorge , Gochez Delfy , Jeannin Morgan , Magongo Mduduzi Welcome , Loi Camille , Bucher Karen , Moulin Gerard , Erlacher-Vindel Elisabeth 
Published: March 2022

Abstract
The global action plan (GAP) on antimicrobial resistance (AMR) advocated the development of national action plans on AMR and the implementation of plans aimed at preventing, combating and monitoring AMR. The World Organisation for Animal Health (OIE)’s strategy on AMR and the prudent use of antimicrobials is aligned with the GAP and recognizes the importance of a One Health approach. This paper reviews the goals, tools and strategies that the OIE has in place to support its Members, envisioning an increased awareness of them and ultimately an increased implementation of the OIE standards. The OIE standards are endorsed by vote of all the 182 Members and are recognized by the World Trade Organization (WTO). The OIE List of Antimicrobial Agents of Veterinary Importance, which includes specific recommendations on the use of antimicrobial agents, is also of particular importance for antimicrobial stewardship. OIE’s antimicrobial use (AMU) data collection started in 2015 and has been developed in particular to measure trends in AMU. An annual report is published as an output of this data collection. An AMU IT database system is being developed. The OIE provides assistance to its 182 Members to strengthen the implementation of OIE standards via its support of good governance, the Performance of Veterinary Services (PVS) Pathway, PVS Veterinary Legislation Support Program and training of veterinarians and veterinary paraprofessionals. In parallel, the OIE Observatory is a recent initiative, specifically targeting the monitoring of the implementation of the OIE standards. Cooperation agreements between the OIE and intergovernmental organizations and non-governmental organizations are instrumental for the increase of the dissemination and implementation of the OIE standards and guidelines.
Novel Fluorescent Nano Carbon Quantum Dots Derived From Lactarius Hatsudake for High Selective Vitamin B12 Detection
Authors: Xiang Yingying , Song Fei , Jiang Lei , Liu Ze , Tu Yujiao 
Published: March 2022

Abstract

Background
VB12 is involved in the production of bone marrow red blood cells, preventing pernicious anemia and brain nerve damage.

Objective
A large edible fungus Lactarius hatsudake (Lh) was used as a carbon source to produce fluorescent carbon dots (CDs) with high quantum yield and high photostability by a one-step hydrothermal method.

Method
The structure and optical properties of Lh-CDs were characterized by XRD, XPS, FTIR, and UV-Vis, and the stability of Lh-CDs was studied. The maximum excitation wavelength and emission wavelength of Lh-CDs were 324 and 408 nm, respectively, and the average fluorescence lifetime was 2.29 ns.

Results
The linear range is 0∼20 μM (R2 = 0.9972) with a detection limit of 36.9 nM. At the same time, the mechanism of fluorescence quenching was internal filtration effect.

Conclusions
It showed that Lh-CDS had good selectivity, high sensitivity, and good anti-interference ability to VB12, which provided a new detection method for VB12.Highlights The fluorescence intensity of the LH-CDs could be effectively quenched by VB12.

Highlights
The fluorescence intensity of the LH-CDs could be effectively quenched by VB12.
Experiential and Analytical Price Evaluations: How Experiential Product Description Affects Prices
Authors: Monnier Arnaud , Thomas Manoj 
Published: March 2022

Abstract
Quantity can be described using perceptual units (e.g., bags, pieces) or standardized units (e.g., ounces, grams). Merely making perceptual units more salient in quantity description can increase perceived economic value. Even when the objective information and numerosity are kept constant, merely presenting the perceptual unit first (e.g., Lay’s Chips 14 snack bags, 14 oz. of chips in snack bags of 1 oz. each) increases willingness to pay compared to presenting the standardized unit first (e.g., Lay’s Chips 14 oz., 14 oz. of chips in snack bags of 1 oz. each). This occurs because perceptual units activate more experiential evaluations whereas standardized units activate more analytical evaluations. An archival study shows that retailers charge higher unit prices for products when perceptual units are salient in quantity description. Six preregistered experiments show that even when both units are available, merely increasing the attentional salience of perceptual units increases willingness to pay. The demonstration that the mere salience of experiential information can alter subjective value offers new insights into the psychology of market prices.
A “Serious Game” to Explore Alternative Forestry Futures
Authors: Bengston David N , Westphal Lynne M , Dockry Michael J , Crabtree Jason 
Published: March 2022

Abstract
Serious games are designed to achieve specific educational or other practical purposes beyond pure entertainment. These games take many different forms—from card decks to massive multiplayer online games—and have proliferated across diverse fields. This note introduces IMPACT: Forestry Edition, a serious board game designed to help forestry professionals and stakeholders think more broadly, critically, and creatively about the future of forestry. We describe the game and feedback from beta testing and discuss the advantages and potential drawbacks of gaming methods. A “print and play” version of the game is included as supplemental material. Serious games can make an important contribution to forestry by engaging and informing diverse stakeholders and generating insight that other methods cannot.
A case of sporadic Peutz-Jeghers syndrome presenting as multiple intussusceptions
Authors: Gorji Leva , Huish Grant , Morgan Joshua , Levy Paul 
Published: March 2022

Abstract
Peutz-Jeghers syndrome (PJS) is an autosomal dominant mutation of the STK11/LKB1 gene on chromosome 19 often characterized by mucocutaneous pigmentation, hamartomatous polyps, anemia, gastrointestinal bleeding and intussusception. We present the case of a 21-year-old female with no pertinent family history who received the diagnosis of PJS after presenting to the hospital with two episodes intussusception. Patients with PJS have an increased lifetime risk of developing stomach, small bowel, colon, pancreatic, breast, cervical, uterus and testicular cancer requiring religious surveillance at an early age.
EUS-FNA Diagnosis of a Metastatic Adult Granulosa Cell Tumor in the Stomach
Authors: Nikas Ilias P , Sepsa Athanasia , Kleidaradaki Evangelia , Salla Charitini 
Published: March 2022

AbstractGranulosa cell tumors are uncommon ovarian neoplasms, predominantly of the adult type (AGCT). In this report, we present a rare case of a patient with metastatic AGCT to the stomach diagnosed with endoscopic ultrasound–guided fine-needle aspiration (EUS-FNA). A 61-year-old woman without a history of AGCT underwent both a vaginal and an abdominal ultrasound that showed a solid and cystic ovarian mass along with a solid mass in the gastric antral wall. Subsequently, an EUS-FNA was performed to assess the gastric lesion. Cytologic findings showed high cellularity, and the groups of neoplastic cells invaded the muscle layer of the stomach. Notably, these cells formed Call-Exner bodies, whereas some nuclei exhibited nuclear grooves. Immunohistochemistry was performed, revealing positivity for α-inhibin, calretinin, and CD56 in the neoplastic cells, whereas chromogranin, synaptophysin, CD117, and DOG1 were negative. The combination of clinical presentation, radiology, cytomorphology, and immunohistochemistry could facilitate the diagnosis of metastatic AGCT and the management of such patients.
Macroprolactinoma-Induced Syndrome of Inappropriate Antidiuresis and Its Reversal with Dopamine Agonist Therapy
Authors: Schlegel Amnon 
Published: March 2022

Abstract
Hyponatremia is an uncommon manifestation of pituitary adenomas. Herein, I report a case of syndrome of inappropriate antidiuresis (SIAD) caused by a macroprolactinoma that rapidly resolved with dopamine agonist therapy. A 29-year-old White woman presented with euvolemic, hypotonic hyponatremia, normal thyroid and glucocorticoid axes, and inappropriately concentrated urine. She was found to have a 1.2-cm sellar mass. Investigation of additional pituitary axes revealed an elevated prolactin level of 193.7 ng/mL. The SIAD experienced by the patient corrected rapidly with initiation of cabergoline. The patient could not tolerate dopamine agonist therapy, and after 1 year, she underwent transsphenoidal resection of the mass after the prolactin began to increase. Pathological examination confirmed the diagnosis of macroprolactinoma. There was no recurrence of the tumor, and the patient continued to have normonatremia and normoprolactinemia 7 years after her operation. To my knowledge, this is the first report in the literature of pathology-confirmed macroprolactinoma marked by SIAD that showed rapid normalization of water metabolism with dopamine agonist therapy.
In depth search of the Sequence Read Archive database reveals global distribution of the emerging pathogenic fungus Scedosporium aurantiacum
Authors: Irinyi Laszlo , Roper Michael , Meyer Wieland 
Published: March 2022

Abstract

Scedosporium species are emerging opportunistic fungal pathogens causing various infections mainly in immunocompromised patients, but also in immunocompetent individuals, following traumatic injuries. Clinical manifestations range from local infections, such as subcutaneous mycetoma or bone and joint infections, to pulmonary colonization and severe disseminated diseases. They are commonly found in soil and other environmental sources. To date S. aurantiacum has been reported only from a handful of countries. To identify the worldwide distribution of this species we screened publicly available sequencing data from fungal metabarcoding studies in the Sequence Read Archive (SRA) of The National Centre for Biotechnology Information (NCBI) by multiple BLAST searches. S. aurantiacum was found in 26 countries and two islands, throughout every climatic region. This distribution is like that of other Scedosporium species. Several new environmental sources of S. aurantiacum including human and bovine milk, chicken and canine gut, freshwater, and feces of the giant white-tailed rat (Uromys caudimaculatus) were identified. This study demonstrated that raw sequence data stored in the SRA database can be repurposed using a big data analysis approach to answer biological questions of interest.

Lay summary
To understand the distribution and natural habitat of S. aurantiacum, species-specific DNA sequences were searched in the SRA database. Our large-scale data analysis illustrates that S. aurantiacum is more widely distributed than previously thought and new environmental sources were identified.
The JCMT BISTRO Survey: multiwavelength polarimetry of bright regions in NGC 2071 in the far-infrared/submillimetre range, with POL-2 and HAWC+
Authors: Fanciullo Lapo , Kemper Francisca , Pattle Kate , Koch Patrick M , Sadavoy Sarah , Coudé Simon , Soam Archana , Hoang Thiem , Onaka Takashi , Le Gouellec Valentin J M , Arzoumanian Doris , Berry David , Eswaraiah Chakali , Chung Eun Jung , Furuya Ray , Hull Charles L H , Hwang Jihye , Johnstone Douglas , Kang Ji-hyun , Kim Kyoung Hee , Kirchschlager Florian , Könyves Vera , Kwon Jungmi , Kwon Woojin , Lai Shih-Ping , Lee Chang Won , Liu Tie , Lyo A-Ran , Stephens Ian , Tamura Motohide , Tang Xindi , Ward-Thompson Derek , Whitworth Anthony , Shinnaga Hiroko 
Published: March 2022

ABSTRACTPolarized dust emission is a key tracer in the study of interstellar medium and of star formation. The observed polarization, however, is a product of magnetic field structure, dust grain properties, and grain alignment efficiency, as well as their variations in the line of sight, making it difficult to interpret polarization unambiguously. The comparison of polarimetry at multiple wavelengths is a possible way of mitigating this problem. We use data from HAWC+ /SOFIA and from SCUBA-2/POL-2 (from the BISTRO survey) to analyse the NGC 2071 molecular cloud at 154, 214, and 850 $\mu$m. The polarization angle changes significantly with wavelength over part of NGC 2071, suggesting a change in magnetic field morphology on the line of sight as each wavelength best traces different dust populations. Other possible explanations are the existence of more than one polarization mechanism in the cloud or scattering from very large grains. The observed change of polarization fraction with wavelength, and the 214-to-154 $\mu$m polarization ratio in particular, are difficult to reproduce with current dust models under the assumption of uniform alignment efficiency. We also show that the standard procedure of using monochromatic intensity as a proxy for column density may produce spurious results at HAWC+wavelengths. Using both long-wavelength (POL-2, 850 $\mu$m) and short-wavelength (HAWC+, $\lesssim 200\, \mu$m) polarimetry is key in obtaining these results. This study clearly shows the importance of multi-wavelength polarimetry at submillimetre bands to understand the dust properties of molecular clouds and the relationship between magnetic field and star formation.
Sensitivity tests of cosmic velocity fields to massive neutrinos
Authors: Zhou Shuren , Liu Zhenjie , Ma Qinglin , Liu Yu , Zhang Le , Li Xiao-Dong , Wang Yang , Wang Xin , Yu Yu , Yu Hao-Ran , Zheng Yi 
Published: March 2022

ABSTRACT
We investigate impacts of massive neutrinos on the cosmic velocity fields, employing high-resolution cosmological N-body simulations provided by the information-optimized CUBE code, where cosmic neutrinos are evolved using collisionless hydrodynamics and their perturbations can be accurately resolved. In this study, we focus, for the first time, on the analysis of massive-neutrino-induced suppression effects in various cosmic velocity field components of velocity magnitude, divergence, vorticity, and dispersion. By varying the neutrino mass sum Mν from 0 to 0.4 eV, the simulations show that the power spectra of vorticity – exclusively sourced by non-linear structure formation that is affected by massive neutrinos significantly – are very sensitive to the mass sum, which potentially provide novel signatures in detecting massive neutrinos. Furthermore, using the χ2 statistic, we quantitatively test the sensitivity of the density and velocity power spectra to the neutrino mass sum. Indeed, we find that the vorticity spectrum has the highest sensitivity, and the null hypothesis of massless neutrinos is incompatible with both vorticity and divergence spectra from Mν = 0.1 eV at high significance (P-value = 0.03 and 0.07, respectively). These results demonstrate clearly the importance of peculiar velocity field measurements, in particular of vorticity and divergence components, in determination of neutrino mass and mass hierarchy.