bluuebunny/crossref_metadata_2025_split huggingface dataset:
The senior high school students' perception on the use of Google Classroom in online English learning
Authors: Kurniawan Heri , Suharjito Bambang , Ariyanto Sugeng 
Published: April 2022

This research was intended to describe the eleventh-grade students’ perception on the use of Google Classroom in online English learning at SMAN 1 Ngoro Mojokerto. Hence, this research used a descriptive research design because the objective of the study was to describe the students’ perception on the use of Google Classroom for online English learning during the pandemic. The data of this research were collected from the questionnaire. Further, the data of the research was calculated in the form of percentages and analyzed using quantitative analysis. The finding and discussion described the appropriateness of comfort, the content, efficient in use, language in Google Classroom application, clarity of the material, and fun to use. The result of the research showed that overall, the majority of the students had positive responses to every indicator and agreed that Google Classroom could facilitate them in an English classroom during pandemic situations.
Keyword: Students’ Perception; Google Classroom; Online English learning
Investigating Teachers' Strategies in Applying Online Teaching Platforms to Teach English during Covid-19 Pandemic
Authors: Damayanti Fitria Saqinah , Sudarsono Sudarsono , Ariyanto Sugeng 
Published: April 2022

Abstract
In early 2020, face-to-face learning has been shifted to online learning caused by the Covid-19 pandemic. Therefore, this study was conducted to examine the online teaching platform used by English teachers and their strategies to attract students' active participation. The researcher chose a case study as the research design. Meanwhile, the data were collected by interviewing four English teachers and validated by conducting interviews with four students from each teacher and observing the online class activities. Then, the data collected was analyzed using the theory of Miles and Huberman (1994). The result showed applications that teachers used to teach online classes. In addition, they had some teaching strategies that focused more on how the teacher attracted the students to participate in the class actively. However, teachers still needed to develop teaching strategies that focus on the active participation of students and their learning goals.
Keywords: Online teaching platforms, teaching strategies, online learning.
DETECTION OF GENDER BIASED USING DIF (DIFFERENTIAL ITEM FUNCTIONING) ANALYSIS ON ITEM TEST OF SCHOOL EXAMINATION YOGYAKARTA
Authors: Ajeng Wahyuni  
Published: April 2022

This study aim to detect an item that biased on gender (divided by male and female) by DIF (Differential Item Functioning) on school examination test in Yogyakarta regency in islamic education subject for third grade of Senior High School based on item respons theory . This research is quantitative research and the subject for this study are 937 Senior High School students in Yogyakarta regency taken by their response sheets on 50 items test with of choices of islamic education subject in school examination at year 2016. Data analysis based on Rasch model with Winstep 3.73 software. The research found that the there are item that biased on certain gender, there are 26 items that have probabilitas value less than 0.05 and t-value outside the range of -1.96 ≤ t-value ≤ 1.96, based on plot from the result analysis there are 14 items (6, 9, 10, 13, 15, 16, 20, 25, 28, 30, 31, 32, 41, 48) tend to give advantage for Male, and there are 12 items (1, 11, 12, 14, 21, 22, 29, 38, 40, 43, 46, 50) tend to give advantage for Female.
Deterioration Characteristic and Constitutive Model of Red-Bed Argillaceous Siltstone Subjected to Drying-Wetting Cycles
Authors: Zha Fusheng , Huang Kai , Kang Bo , Sun Xianguo , Su Jingwen , Li Yunfeng , Lu Zhitang 
Published: April 2022

Abstract
Red-bed argillaceous siltstone is one of main types of rocks composing unstable slopes on both banks of water diversion project from the Yangtze to Huaihe River and is prone to deterioration after subjected to drying-wetting cycle conditions during water diversion project operation. The study of the damage degradation and the constitutive relationship of rocks subjected to drying-wetting cycle process is therefore of critical scientific importance. In this paper, laboratory tests were conducted to investigate the effect of drying-wetting cycles on the mechanical properties and microstructural characteristics. The experimental results show that the microstructure of the sample surface is no longer dense and uniform and the porosity of tested samples significantly increases with drying-wetting cycles increasing. After subjected to cycles of drying-wetting, the compaction stage of the stress-strain curve becomes longer with more pronounced nonlinear features, while uniaxial compression strength (UCS) and elastic modulus drop obviously. Combined with the evolution characteristics of microstructure found as the porosity grew, UCS and elastic modulus gradually decline. Additionally, from the perspective of energy analysis, the input energy density and dissipated energy density gradually extended with the increasing strain, and the elastic energy density increased first and then declined. As the number of drying-wetting cycles increases, the energy density of samples all present linear fell. Based on the evolution of dissipated energy, a new damage model of red-bed argillaceous siltstone subjected to drying-wetting cycles was established by introducing compaction coefficient. The coefficients of determination (R2) of the constitutive model are always greater than 0.85, indicating that the proposed model is generally in good agreement with the experimental data under different drying-wetting cycles. This paper has specific research and reference value to understand the damage evolution characteristics of red-bed argillaceous siltstone under cyclic drying-wetting.
Embedding employability skills in vocational education and training: What works best for students’ self-evaluation and aspirations?
Authors: Romanova Olga 
Published: April 2022

This paper investigates how explicit integration of employability skills into vocational education and training (VET) affects students’ perceived skills. Perceived or self-evaluated skills are often inaccurate perceptions of the real skills’ possession, but nonetheless they play a profound role in graduates’ career decisions. Confidence that resulted from positive self-evaluations supports the efforts and aspirations during school-to-work transitions. Thus, they are considered to be an important educational outcome supporting employability. The purpose of the study is to enrich understanding of relationship between students’ self-evaluations of employability skills and different teaching practices.
The analysis employs self-evaluations and entrepreneurial intentions of the Russian VET students collected with Monitoring of education markets and organizations in 2020 (n = 9 178). It focuses on social, self-learning and entrepreneurial skills, which are part of the VET national curriculum. The findings show that explicit embedding and integration of employability skills in the curriculum is significantly related to more positive self-evaluations of social and self-learning skills. Moreover, students, who were explicitly taught entrepreneurial skills, are more likely to plan to establish their own enterprise after graduation. Despite being effective, the explicit integration approach is revealed to be not dominant. Further research on the reasons behind this is needed for development of properly informed policy.
A New Kinetic Assay Method for Effective Scale Inhibitor Concentration Determination with Low Detection Limit
Authors: Dai Zhaoyi , Ko Saebom , Wang Xin , Dai Chong , Paudyal Samridhdi , Zhao Yue , Li Wei , Leschied Cianna , Yao Xuanzhu , Lu Yi-Tsung , Kan Amy , Tomson Mason 
Published: April 2022

Summary
Scale inhibitors are widely used for mineral scale control in various industries, including oil and gas productions, geothermal energy acquisitions, and heat exchanger scale control to mention a few. In most applications, these scale inhibitors are effective at substoichiometric concentrations (e.g., 1 mg/L or lower), and the optimization of these applications is based on the ability to accurately measure the effective inhibitor concentration at such low concentrations. For example, the continuous treatment injection rate, the squeeze treatment frequency, or the batch treatment schedule need to be optimized to ensure the minimum inhibitor concentration (MIC) is achieved during production. However, the non- or low-phosphorous polymeric scale inhibitor concentration determination is difficult using inductively coupled plasma (ICP)-optic emission spectroscopy/mass spectrometry or ion chromatography, especially at mg/L level concentrations due to their high detection limits. The recently developed hyamine method or high-pressure liquid chromatography (HPLC) method involves intensive labor and high costs. Furthermore, in the complex oilfield operational conditions, the presence of other chemicals (e.g., surfactants, biocides, and corrosion inhibitors), the potential degradation of scale inhibitors and the use of combination scale inhibitors require the measurement of effective scale inhibitor concentration, which cannot be accomplished by the traditional methods. In this study, a new kinetic assay method has been developed to determine the effective scale inhibitor concentration with limits of detection (LODs) less than or around 0.1 mg/L for most cases. This method uses a continuous stirring tank reactor (CSTR) apparatus and is developed based on the linear correlation between the effective inhibition concentration and the measured critical time when laser signal changes. The results show that the inhibitor concentrations of various non- or low-phosphorous polymeric scale inhibitors in synthetic field brine, laboratory solutions, and real oilfield brines can be accurately determined at mg/L level, or lower, with less than 10% error. The method is robust, accurate, and much less time- or labor-consuming than other existing methods especially for non- or low-phosphorous polymeric scale inhibitors.
Modeling and optimization of the pyrolysis oil production process from polypropylene for the production of aviation kerosene
Authors: Santos Heraclito Alexandre dos , Santos Igor José Boggione , Quintão Cristiane Medina Finzi , Knupp Vagner Fernandes , Lofrano Renata Carolina Zanetti , de Oliveira Eliane Cristina , Samanamud Gisella Lamas , Amaral Mateus Souza , França Alexandre Boscaro , Pereira Mariana Arruda , Silva Matheus Teixeira Araújo , Loures Carla Cristina Almeida , Carneiro Mozart Dos Santos , Ponciano Jéssica Amaral Pereira , Naves Luzia Lima Rezende , Naves Fabiano 
Published: April 2022

Abstract
One of the greatest challenges in the world is in the final disposal of plastics in order to reduce the effect of its polluting potential. Thus, the application of pyrolysis processes in generating products of interest such as fuel oils can be part of the solution. In addition to reducing greenhouse gas emissions to the atmosphere, oil can enter the supply chain after the cracking process in petrochemical industries. In this context, this work used statistical modeling of the response surface linked to the Normal Boundary Intersection algorithm, aiming at a higher yield of oil production and major selectivity of recycled polypropylene pyrolysis. From the analysis of the mechanisms proposed in the literature with the modeling and optimization in this work, it was possible, from a kaolin mass of 9.12 g and a heating ramp of 19.37°C/min, to obtain higher percentages of aviation kerosene as well as a satisfactory performance.
Point prevalence of SARS-CoV-2 infection in Sweden at six time points during 2020
Authors: Groenheit Ramona , Beser Jessica , Berenzon Sharon Kühlmann , Galanis Ilias , Straten Edward , Duracz Jan , Rapp Marie , Hansson Disa , Mansjö Mikael , Söderholm Sandra , Muradrasoli Shaman , Risberg Anna , Ölund Richard , Wiklund Andreas , Metzkes Kristoffer , Lundberg Matilda , Bacchus Philip , Wisell Karin Tegmark , Bråve Andreas 
Published: April 2022

Abstract
BackgroundTo estimate the prevalence and understand the dissemination of SARS-CoV-2 in Sweden, the Public Health Agency of Sweden, with support from the Swedish Armed Forces, conducted a series of point prevalence surveys between March and December 2020.MethodsSampling material and instructions on how to perform self-sampling of the upper respiratory tract were delivered to the homes of the participants. Samples were analysed by real-time PCR, and the participants completed questionnaires regarding symptoms.FindingsThe first survey in the Stockholm region in March, including 707 participants, showed a SARS-CoV-2 prevalence of 2.5%. The following five surveys, performed on a national level, with between 2,461 and 2,983 participants, showed SARS-CoV-2 prevalences of 0.9% (April), 0.3% (May), 0.0% (August), 0.0% (September), and 0.7% (December).All positive cases responding to the questionnaires regarding experienced symptoms had experienced symptoms two weeks before sampling up until the day of sampling.InterpretationNone of the individuals shown to be PCR-positive were asymptomatic at the time of sampling, including 14 days prior to sampling. This is in contrast to many other surveys, where a substantial proportion of positive cases are reported to be asymptomatic.In line with an increasing testing capacity and consecutive inclusion of all symptomatic individuals in the case definition for testing, our surveys demonstrate a decreasing ratio between notified cases and shown prevalence throughout the year.
Identification of key genes and pathways in postoperative cognitive dysfunction: Potential therapeutic drugs discovered using bioinformatics analysis
Authors: Dou Xiaoke , Dai Maosha , Ma Jiamin , Sun Yan , Chen Rui , Lin Yun 
Published: April 2022

Abstract
Background: Postoperative cognitive dysfunction (POCD) is a common complication after general anesthesia surgery, and the mechanism of POCD has not been completely studied yet. We aim to use bioinformatics to identify the potential key genes and pathways involved in the mechanism of POCD and explore the potential targeted drugs to treat POCD.Methods: Genes related to POCD were detected using pubmed2ensemble, then the Gene Ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway of these genes were annotated and visualized using GENECODIS. A protein‑protein interaction (PPI) network was constructed by STRING and visualized in Cytoscape, and the Molecular Complex Detection (MCODE) was used to classify the candidate gene modules. Candidate genes were further validated again via Metascape and Cluego for a GO enrichment and KEGG pathway analysis. Finally, Drug-Gene Interaction Database (DGIDB) was used to identify the related drugs.Results: We identified 70 genes related to POCD and as follows 48 candidate genes were obtained following GO and KEGG enrichment analysis. 39 genes were obtained from a PPI network and one gene module including 12 crucial genes were obtained using the MCODE. Lastly, 5 genes including ACE, IL6, TNF, CCL2, CXCL8 related to 3 main signaling pathways---- hypertrophic cardiomyopathy, viral protein interaction with cytokine and cytokine receptor, and IL17 signaling pathway. Furthmore,26 targeted drugs were explored as potential therapeutic agents. Conclusion: In this study, we ultimately identified 5 target genes targetable by 26 drugs for POCD, related to 3 main signaling pathways.
LAMP2A facilitates lipid droplet production and chemoresistance of colorectal cancer cells by maintaining ING5 protein stability
Authors: Xuan Ying , Shi Shuai , Xue Hang , Liu Kun , Han Wei-li , Li Benchang , Zhang Rui , Nie Yongzhan , Zheng Huachuan 
Published: April 2022

Abstract
Background
LAMP2A is a lysosome-associated membrane glycoprotein, which acts as a receptor for substrate proteins of chaperone-mediated autophagy. This study investigated the effect of LAMP2A in colon tumorigenesis and chemoresistance.
Methods
LAMP2A mRNA and protein expression in colorectal cancer and normal tissue was detected by RT-PCR, immunohistochemistry, and western blot. HCT116 and DLD-1 cell lines and the corresponding transfected cells were assessed by measurement by proliferation, apoptosis, migration, invasion, and droplet formation.
Results
LAMP2A was down-regulated in colorectal cancer at the mRNA level (p < 0.05), but up-regulated at the protein level (p < 0.05). LAMP2A protein overexpression was negatively correlated with lymphatic invasion, lymph node metastasis, liver metastasis and TNM staging of colorectal cancer (p < 0.05), as well as unfavorable prognosis of Tis-T2 colorectal cancer patients (p < 0.05). LAMP2A knockdown suppressed proliferation, migration and invasion, and induced apoptosis of colorectal cancer cells (p < 0.05), along with under-expression of acetyl-CoA carboxylase 1(ACC1), ATP-citrate lyase (ACL), Bcl-2, ING5, NF-κB, and Bax overexpression, while LAMP2A overexpression had the opposite results. There was a positive relationship between LAMP2A and ING5 expression in colorectal cancer (p < 0.05). Treatment with lysosome or NF-κB inhibitor decreased ING5 expression in LAMP2A transfectants. ING5 degradation was delayed in LAMP2A transfectants after cycloheximide exposure (p < 0.05). ING5 knockdown reduced the expression of ACC1, ACL and NF-κB, and the formation of lipid droplets, while the opposite was true in ING5 overexpression. There was higher expression of ING5, LAMP2A, ACC1, ACL, and NF-κB, and stronger lipogenesis in 5-FU-resistant cancer cells. ING5 and/or LAMP2A silencing caused down-regulation of ACC1, ACL, and NF-κB, and lipogenesis in both 5-FU-resistant cancer cells.
Conclusions
LAMP2A overexpression was positively correlated with colorectal carcinogenesis, aggressiveness and poor prognosis of colorectal cancer. LAMP2A may contribute to lipogenesis and subsequent chemoresistance by inhibiting lysosomal degradation of ING5 via the NF-κB signaling pathway.
Face-to-face vs. Emergency Remote Teaching during the Covid-19 lockdown. A comparative analysis of Ecuadorian undergraduate polytechnic students' performance.
Authors: ESTRELLA FELIX 
Published: April 2022

Abstract
The COVID-19 outbreak has changed education, mainly by shifting face-to-face classes to online sessions. Online courses are not new as many educational institutions offer distance or hybrid learning courses. However, emergency remote teaching (ERT), into which education has shifted, attains differences. This study aims to identify student performance differences depending on teaching modality (face-to-face and ERT). Studies considering the COVID-19 pandemic and information originating from Ecuador are scarce, making this study relevant. This quantitative research used a two-way ANOVA to analyze skills results from exams given in the academic year 2019 (face-to-face) and 2020 (ERT). Results were not statistically significant at p < .05, which concurs with the existing literature.
Experiences of Cancer Patients about Seeking Health Information: A Qualitative Study
Authors: Mousavi Seyedeh Leila Mousavi , Saki Mandana , Mohammadipour Fatemeh , Gholami Mohammad , Almasian Mohammad , Pour Fatemeh Jafari 
Published: April 2022

Abstract
Objective: Searching for health information is an important strategy in dealing with cancer that contributed to the improved management of cancer. This study aimed to explore the experiences of cancer patients seeking health information.Methods: The 18 participants were selected by purposive sampling and data were collected through semi-structured in-depth interviews. Data analysis was performed through conventional content analysis approach method at the same time as data collection.Results: Data analysis led to the emergence of three central categories, including “optimal cancer management”, “poor information dissemination system” and “perceived health literacy”.Conclusion: Knowing how cancer patients obtain health information can form the basis to promote patients’ health literacy and design a health information dissemination system tailored to the patients’ needs.
Abundance and characteristics of microplastics in major urban wetlands of Dhaka, Bangladesh
Authors: Mercy Fariha Tahsin , Alam A.K.M. Rashidul , Akbor Md. Ahedul 
Published: April 2022

Abstract
The study was performed to evaluate the abundance and characteristics of MPs in water, sediment, and fish samples of three major urban lakes, namely Dhanmondi Lake, Gulshan Lake, and Hatir Jheel Lake in Dhaka, Bangladesh. The abundance of microplastics varied from 0-9 items/L in surface water, 0-16 items/kg in sediment, and 0-17 items/individual; 0-4.88 items/g in the gastrointestinal tract (GIT) of test fish species, respectively. Highest abundance of microplastic in an individual fish was observed in Oreochromis mossambicus from Dhanmondi Lake. The samples were visually observed under a stereo microscope, which showed the dominant type of microplastics in both water and sediment samples were films followed by micro pellets, fragments, fibers, and in fish samples pellets and foams were dominant. According to the Fourier Transform Infrared analysis (FTIR) the dominant polymers in the analyzed samples were High density polyethylene (HDP), Ethylene Vinyl Acetate (EVA), Polyvinyl chloride (PVC), Polycarbonate (PC), Cellulose Acetate (CA), and Polypropylene (PP). In water and sediment samples of Gulshan Lake, MPs were relatively higher than in other lakes, and in fish samples of Dhanmondi Lake MPs were higher. The results of this study indicate that MPs were abundant in studied lakes and suggested a high level of microplastic contamination occurred not only in the water and sediment but also in the resident fishes. The implication of the finding suggests that the presence of MPs in urban lakes has raised concerns about the potential human health impact.
Molecular Research on the Effect of IL10 Gene Polymorphism on Obesity Parameters in Highly Physically Active Young Men
Authors: Maculewicz Ewelina , Mastalerz Andrzej , Antkowiak Bożena , Antkowiak Oktawiusz , Borecka Anna , Garbacz Aleksandra , Szarska Ewa , Dzitkowska-Zabielska Magdalena , Rusin Paweł , Cywińska Anna , Białek Agnieszka , Cięszczyk Paweł 
Published: April 2022

Abstract
The main aim of this study was to investigate the association between 5 polymorphisms of the interleukin 10 (IL10) gene with body composition parameters in physically active young men. A cohort of 131 male students was enrolled and the following IL10 SNPs were analyzed: rs1518111, rs1878672, rs3024496, rs3024498 and rs3024505. The subjects were divided into groups depending on obesity parameters: body mass index (BMI) and fat percentage (fat %). Statistical analysis was conducted for a single locus and haplotypes, an association between SNPs and body composition parameters were tested with four genetic models: dominant, recessive, codominant and overdominant mode of inheritance (MOI).The results showed statistically significant association with BMI for CCGTA haplotype in additive model (score = -2.00, p = 0.04) and in dominant model (score = -2.30, p = 0.02). The obtained results indicate the significant participation of IL10 polymorphisms in the regulation of body weight in physically active people.