bluuebunny/crossref_metadata_2025_split huggingface dataset:
A hierarchical performance evaluation approach for the sustainability of smart grid
Authors: Pal Chandra , Shankar Ravi 
Published: May 2022

Purpose
The purpose of this study is to establish a hierarchy of critical success factors to develop a framework for evaluating the performance of smart grids from a sustainability perspective.

Design/methodology/approach
The fuzzy analytical hierarchy process is used in this study to assess and determine the relative weight of economic, operational and environmental criteria. At the same time, the evidential reasoning algorithm is used to determine the belief degree of expert’s opinion, and the expected utility theory for the crisp value of success factors in performance estimation.

Findings
The finding reveals that success factors associated with the economic criteria receive significantly more attention from the expert group. Sensitivity analysis indicates the ranking of consumer satisfaction remains stable no matter how criteria weights are changed, which verifies the robustness and effectiveness of the proposed model and evaluation results.

Originality/value
The study presents a solid mathematical framework for collaborative system modeling and systematic analysis. Managers and stakeholders may use the proposed technique as a flexible tool to improve the energy system’s resiliency in a systematic way.
FESM-based approach for stiffness modeling, identification and updating of collaborative robots
Authors: Hu Mingwei , Sun Hongwei , Liao Liangchuang , He Jiajian 
Published: May 2022

Purpose
The purpose of this paper is to introduce a method for stiffness modeling, identification and updating of collaborative robots (cobots). This method operates in real-time and with high precision and can eliminate the modeling error between the actual stiffness model and the theoretical stiffness model.

Design/methodology/approach
To simultaneously ensure the computational efficiency and modeling accuracy of the stiffness model, this method introduces the finite element substructure method (FESM) into the virtual joint method (VJM). The stiffness model of the cobots is built by integrating several 6-degree of freedom virtual joints that represent the elastic deformation of the cobot modules, and the stiffness matrices of these modules can be identified and obtained by the FESM. A model-updating method is proposed to identify stiffness influence coefficients, which can eliminate the modeling error between the actual prototype model and the theoretical finite element model.

Findings
The average relative error and the cycle time of the proposed method are approximately 6.14% and 1.31 ms, respectively. Compared with other stiffness modeling methods, this method not only has high modeling accuracy in high dexterity poses but also in low dexterity poses.

Originality/value
A hybrid stiffness modeling method is introduced to integrate the modeling accuracy of the FESM into the VJM. Stiffness influence coefficients are proposed to eliminate the modeling error between the theoretical and actual stiffness models.
Relationship follows technology! How Industry 4.0 reshapes future buyer-supplier relationships
Authors: Veile Johannes Wolfgang , Schmidt Marie-Christin , Müller Julian Marius , Voigt Kai-Ingo 
Published: May 2022

Purpose
This study analyzes how technological changes in the context of Industry 4.0 influence buyer-supplier relationships (BSRs).

Design/methodology/approach
The study is explorative in nature; hence, an empirical qualitative research design is applied. It bases on 45 expert interviews with managers from German and Austrian industrial companies as empirical data. A qualitative content analysis is conducted to inductively analyze the empirical material and to identify common patterns, themes and categories.

Findings
The paper finds that future transactions are mainly based on digitized, automated procedures, transferring various value creation processes to platforms. BSRs become more intense in nature. Companies consolidate their supplier base by focusing on important strategic suppliers.

Research limitations/implications
As the paper is of exploratory nature, it can only present first qualitative insights. Further studies can extend the results by analyzing and contrasting BSRs in various industries or value chain stages and map differences and similarities, respectively.

Practical implications
The paper's results provide implications for management and corporate practice alike. These help companies to raise Industry 4.0's full potential as for BSRs creating and securing long-term and sustainable competitive advantages.

Originality/value
This paper is among the first to empirically investigate BSRs in the context of Industry 4.0. Providing implications for research and corporate practice, it contributes to tapping Industry 4.0's full potential complementing an extra-organizational perspective.
Supervisor incivility and employee voice: the roles of cognitive reappraisal and psychological distress
Authors: Dedahanov Alisher Tohirovich , Fayzullaev Abdulkhamid Komil ugli , Abdurazzakov Odiljon Sobirovich 
Published: May 2022

PurposeThis work assesses the contingent role of cognitive reappraisal on the link between supervisor incivility and psychological distress and examines the mediating role of psychological distress on the link between supervisor incivility and employee voice, namely, promotive and prohibitive.Design/methodology/approachThe data were collected from 447 highly skilled employees of manufacturing companies. To evaluate the validity of the proposed hypotheses, the authors conducted hierarchical regression analysis and bootstrapping test.FindingsThe findings suggest that despite supervisor incivility, individuals with higher level of cognitive reappraisal are less likely to suffer from psychological distress, whereas individuals with a lower level of cognitive reappraisal are prone to psychological distress when individuals suffer from supervisor incivility. Moreover, the results indicate that psychological distress mediates the link between supervisor incivility and voice, namely, promotive and prohibitive.Originality/valueThis work is the first to investigate the contingency role of cognitive reappraisal on the link between supervisor incivility and psychological distress and the mediating role of psychological distress on the link between supervisor incivility and employee voice.
Green drivers and green enablers in pharmaceuticals supply chain: in the context of an emerging economy
Authors: Sabat Kali Charan , Krishnamoorthy Bala , Bhattacharyya Som Sekhar 
Published: May 2022

PurposeThe purpose of this study was to comprehend the current state of green supply chain management (GSCM) and its drivers and enablers in the pharmaceutical supply chains (PSCs).Design/methodology/approachThis study developed a model consisting of the factors green drivers, green enablers and green practices. For this study, data were collected from 166 supply chain heads from 124 pharmaceutical companies operating in India. The data was empirically analysed using SmartPLS3 software.FindingsThe study revealed that in Indian PSCs, public pressure, supplier pressure and competitor pressure were the major drivers for GSCM practices and coercive pressures such as pressure from government and regulatory bodies were insignificant drivers. The results indicated that the influence of green drivers and green enablers altered with supply chain flow. Green drivers indicated higher influence at the upstream of PSCs whereas the influence of green enablers was higher at the downstream of PSCs. Furthermore, the study revealed that the factor “green enablers” was a good mediator for the relationship between “green drivers” and “GSCM practices” in PSCs.Research limitations/implicationsThis study was an extension work with the addition of external green drivers to the self-induced organizational activities. Further investigations can be done by including the “green barriers” construct in the conceptual model.Practical implicationsThis research connected the institutional theory with the resource-based view to understanding the role of green drivers and green enablers in greening PSC. For managers and regulators, this study provided clear insights on how to approach different supply chain drivers and enablers to maximize the impact of GSCM practices. Moreover, the findings of this study helped in incorporating knowledge about GSCM into a framework that can be used for defining strategies for setting up a sustainable PSC for pharmaceutical products leading to the development and growth of the pharmaceuticals industry.Originality/valueMost of the earlier studies on GSCM were at the firm level and some studies were at the supply chain level. To further enhance the scope of GSCM theory, this study was conducted at two different levels, first at the complete supply chain level and second at three different levels: upstream, firm-level and downstream.
Safety and effectiveness of nivolumab in Japanese patients with malignant melanoma: Final analysis of a post‐marketing surveillance
Authors: Uhara Hisashi , Tsuchida Tetsuya , Kiyohara Yoshio , Akamatsu Ayumi , Sakamoto Takahiko , Yamazaki Naoya 
Published: May 2022

AbstractNivolumab, a monoclonal antibody against human programmed death 1, was approved for the treatment of melanoma in July 2014 in Japan. Because the Japanese phase II studies (ONO‐4538‐02, ONO‐4538‐08) enrolled small numbers of melanoma patients, post‐marketing surveillance (PMS; JapicCTI‐163 272) was conducted to collect safety data in a larger patient population. We report data for melanoma patients who received nivolumab between July 4, 2014 and February 28, 2017. Data collected included baseline characteristics, laboratory tests, treatment‐related adverse events (TRAE), and overall survival (OS). Of 2069 enrolled patients, 2008 patients were included in the safety analysis population. There were 1030 (51.3%) males, the median age was 69 years, and 269 patients (13.4%) had a performance status of ≥2. The primary tumor sites were cutaneous (34.4%), mucosal (34.2%), acral lentiginous (18.6%), others (6.8%), and unknown (6.3%). TRAE occurred in 62.1% of patients, the most common being hypothyroidism (14.0%), increased aspartate aminotransferase (8.5%), and increased alanine aminotransferase (6.9%). TRAE of special interest in ≥5% of patients were thyroid dysfunction (24.9%), hepatic dysfunction (20.6%), infusion reactions (11.4%), colitis/severe diarrhea (6.3%), and interstitial lung disease (ILD; 5.0%). Several types of TRAE of special interest, which included myasthenia gravis/myocarditis/myositis/rhabdomyolysis (0.9%), venous thromboembolism (0.2%), immune thrombocytopenic purpura (0.1%), and encephalitis (0.0%), were observed in this PMS. Although these TRAE were not reported in previous studies (ONO‐4538‐02, ONO‐4538‐08, CheckMate 066, and CheckMate 037), they have been listed in the current Risk Management Plan. History of ILD and male sex were risk factors for ILD in a multivariable analysis. Age <75 years was a risk factor for hepatic dysfunction. At 12 months, median OS was not reached. In conclusion, these results suggested that there was no concern requiring additional precautions for the safety of nivolumab in Japanese patients with melanoma other than the safety information in the Risk Management Plan.
How Should a Progressive Parliament Advance Proportional Representation?
Authors: White Stuart 
Published: May 2022

AbstractMany supporters of democratic reform in the UK propose both a change in the electoral system to proportional representation (PR) and a shift to a formal (codified and entrenched) constitution. In principle, these two proposals are deeply complementary. There is, however, also a potential tension between them. Specifically, if a future UK government were to treat PR as a matter of ordinary legislation, this would conflict with the democratic constitutionalist principle that major constitutional changes require a more direct and/or robust test of public support, in addition to parliamentary approval—such as in a confirmatory referendum. The article discusses seven possible approaches by which a future progressive Parliament might advance PR. It assesses their strengths and weaknesses with an eye on this tension and other factors. It concludes that the emerging politics around this tension underscores the need for a formal constitution to prevent the UK's constitutional politics becoming subordinated to partisan conflict.
Functional map of the macroglomerular complex of male Helicoverpa armigera
Authors: Liu Xiao‐Lan , Chu Xi , Sun Long‐Long , Wang Ya‐Nan , Xie Gui‐Ying , Chen Wen‐Bo , Liu Yang , Berg Bente G. , An Shi‐Heng , Wang Gui‐Rong , Yin Xin‐Ming , Zhao Xin‐Cheng 
Published: May 2022

AbstractThe mechanism of sex pheromone reception in the male cotton bollworm Helicoverpa armigera has been extensively studied because it has become an important model system for understanding insect olfaction. However, the pathways of pheromone processing from the antenna to the primary olfactory center in H. armigera have not yet been clarified. Here, the physiology and morphology of male H. armigera olfactory sensory neurons (OSNs) were studied using single sensillum recording along with anterograde filling and intracellular recording with retrograde filling. OSNs localized in type A sensilla responded to the major pheromone component cis‐11‐hexadecenal, and the axonal terminals projected to the cumulus (Cu) of the macroglomerular complex (MGC). The OSNs in type B sensilla responded to the behavioral antagonist cis‐9‐tetradecenal, and the axonal terminals projected to the dorsomedial anterior (DMA) unit of the MGC. In type C sensilla, there were 2 OSNs: one that responded to cis‐9‐tetradecenal and cis‐11‐hexadecenol with the axonal terminals projecting to the DMA, and another that responded to the secondary pheromone components cis‐9‐hexadecenal and cis‐9‐tetradecenal with the axonal terminals projecting to the dorsomedial posterior (DMP) unit of the MGC. Type A and type B sensilla also housed the secondary OSNs, which were silent neurons with axonal terminals projected to the glomerulus G49 and DMP. Overall, the neural pathways that carry information on attractiveness and aversiveness in response to female pheromone components in H. armigera exhibit distinct projections to the MGC units.
Preparation and identification of an antioxidant peptide from wheat embryo albumin and characterization of its Maillard reaction products
Authors: Liao Ai‐Mei , Li Xiao‐Xiao , Gu Zeshan , He Jiang‐Ying , Hou Yinchen , Pan Long , Zheng Shuai‐Nan , Zhang Jie , Peng Peng , Hui Ming , Huang Ji‐Hong 
Published: May 2022

AbstractWheat embryo albumin (WEA) extracted from wheat embryo possesses multiple effects including antioxidant, anti‐inflammatory, and immunoregulatory effects. In this study, a single factor experiment was conducted to determine the optimal enzymolysis conditions of WEA. Five components (F1–F5) were obtained via ultrafiltration, among which F3 (molecular weight 3–5 kDa) displayed the best antioxidant activity. WEA and F3 were characterized by transmission electron microscopy, scanning electron microscopy, circular dichroism spectrum analysis, and amino acid composition tests. Results revealed that F3 significantly increased the contents of β‐tablets, aromatic amino acids, and hydrophobic amino acids compared to WEA. LC‐MS/MS analysis demonstrated that F3 had more tyrosine and histidine moieties than WEA. Moreover, analysis of the Maillard reaction products (MRPs) showed that F3‐MRPs had strong browning strength, ultraviolet absorption, higher number of free amino acids, and umami amino acid ratio compared with WEA. In conclusion, enzymolysis can improve the functional properties of WEA, which broadens the application spectrum of WEA in food and pharmaceutical fields.Practical ApplicationThis study provides a new approach for identifying potential antioxidants and developing functional foods from WEA, and broadens the application spectrum of wheat germ resources.
Land Speculation and Suburban Covenants: Racial Capitalism and thePre‐RedliningRoots of Housing Segregation in Syracuse, New York
Authors: Kelly Michael T. 
Published: May 2022

AbstractThis article examines the interrelationship of race, space, and landed property in the historical development of racially segregated housing geographies in the United States. Using archival methods, I directly connect late 18thcentury land speculation to early 20thcentury suburban real estate development based on racially restrictive covenants. I investigate the city of Syracuse—a small, post‐industrial city in Upstate New York on unceded Onondaga Nation land and one of the most racially segregated cities in the US. Dispossession, speculation, and homesteading on the “Central New York Military Tract” generated a racialised, spatialised form of property that real estate capitalists later utilised to create and maintain profit‐oriented suburban segregation. This article extends the historical timeline in studies of residential segregation, provides clarity on dispossession and housing inequity in small and mid‐sized cities, and contributes to understanding how processes of racial capitalism operate through private real estate markets.
The voices of children and young people during COVID‐19: A critical review of methods
Authors: Jörgensen Eva , Koller Donna , Raman Shanti , Olatunya Oladele , Asemota Osamagbe , Ekpenyong Bernadine N. , Gunnlaugsson Geir , Okolo Angela 
Published: May 2022

AbstractAimCritically review research methods used to elicit children and young people's views and experiences in the first year of COVID‐19, using an ethical and child rights lens.MethodsA systematic search of peer‐reviewed literature on children and young people's perspectives and experiences of COVID‐19. LEGEND (Let Evidence Guide Every New Decision) tools were applied to assess the quality of included studies. The critical review methodology addressed four ethical parameters: (1) Duty of care; (2) Children and young people's consent; (3) Communication of findings; and (4) Reflexivity.ResultsTwo phases of searches identified 8131 studies; 27 studies were included for final analysis, representing 43,877 children and young people's views. Most studies were from high‐income countries. Three major themes emerged: (a) Whose voices are heard; (b) How are children and young people heard; and (c) How do researchers engage in reflexivity and ethical practice? Online surveys of children and young people from middle‐class backgrounds dominated the research during COVID‐19. Three studies actively involved children and young people in the research process; two documented a rights‐based framework. There was limited attention paid to some ethical issues, particularly the lack of inclusion of children and young people in research processes.ConclusionThere are equity gaps in accessing the experiences of children and young people from disadvantaged settings. Most children and young people were not involved in shaping research methods by soliciting their voices.
Improved growth with growth hormone treatment in children after hematopoietic stem cell transplantation
Authors: Hoekx Carlijn A. , Bresters Dorine , le Cessie Saskia , Oostdijk Wilma , Hannema Sabine E. 
Published: May 2022

AbstractObjectiveHematopoietic stem cell transplantation (HSCT) can be a curative treatment for malignant and nonmalignant diseases in children but is associated with significant late effects including growth failure. Growth hormone treatment (GHRx) is offered to improve growth, but limited data are available on its effect on adult height (AH). We aim to evaluate the effectiveness of GHRx.DesignSingle‐center retrospective study.PatientsThirty‐four patients who had received GHRx for ≥1 year were matched with two controls each, without GHRx, based on sex, indication for HSCT (malignancy, benign haematological disease or immunodeficiency), age at HSCT and conditioning with/without total body irradiation (TBI). All had reached AH.MeasurementsThe primary outcome measure was the difference between AH and predicted AH (PAH) at start of GHRx or the equivalent age in controls (AH−PAH), calculated according to Bailey and Pinneau.ResultsGHRx was started at age 12.0 ± 2.6 years; median treatment duration was 3.8 years (range 1.7−9.2). AH−PAH standard deviation score (SDS) was significantly higher in growth hormone (GH) treated boys (−0.5 ± 0.7 SDS) than in controls (−1.5 ± 1.0 SDS, p < .001). Girls also had a higher AH−PAH after GHRx (+0.5 ± 0.6 SDS) compared to controls (−0.2 SDS ±0.7, p < .01). AH remained approximately 2 SDS below target height (TH) in treated and untreated individuals. Among GH‐treated children, AH−PAH was higher in those who had received busulfan‐based compared to TBI‐based conditioning.ConclusionGHRx had a significant positive effect on AH compared to PAH, although AH remained far below TH. Higher AH−PAH was observed in girls and in those conditioned without TBI.
Effect of food intake on echocardiographic measurements in healthy elderly
Authors: Gårdinger Ylva , Malmgren Andreas , Hlebowicz Joanna , Dencker Magnus 
Published: May 2022

AbstractObjectiveThis study evaluates whether food intake affects systolic and diastolic echocardiographic measurements in healthy seniors.MethodsThirty healthy subjects 65–70 years of age were investigated with echocardiography, at fasting and then 30, 90, and 180 min after a meal.ResultsAfter 30 min the biggest changes were seen in left ventricular wall stress and myocardial performance index with a decrease of 45% and 33%, respectively, compared to fasting values. Significant (p < .05) increases also were seen in left ventricular stroke volume, left ventricular cardiac output, left ventricular cardiac index, left ventricular outflow velocity‐time integral, peak of early diastolic (E) and late diastolic (A) mitral flow velocities, the E/A ratio, pulsed tissue Doppler peak systolic (s') and early (e') and late (a') diastolic velocities, pulmonary vein peak velocities in systole (S) and diastole (D), mitral annular plane systolic excursion (MAPSE), tricuspid annular plane systolic excursion (TAPSE), and global longitudinal strain (GLS) (increases ranging 6%–19%). After 90 min there remained a decrease in wall stress and myocardial performance index of 31% and 17%, respectively, and smaller, but still significant, changes could be seen in left ventricular stroke volume, left ventricular outflow velocity‐time integral, MAPSE (lateral), TAPSE, GLS, and a few pulsed tissue Doppler peak systolic velocities and late diastolic velocities. An increase also could be seen in deceleration time of E‐wave (DT). After 180 min, all variables except DT were back at baseline or below. No significant changes were seen in S/D ratio, lateral early diastolic velocity (e' lateral) and E/e'ratio.ConclusionsThis study shows that food intake affects commonly used echocardiographic parameters, both systolic and diastolic, in healthy seniors. With a few exceptions, the changes seen in the older population were less pronounced than previous studies in younger subjects.