bluuebunny/crossref_metadata_2025_split huggingface dataset:
Uji Kualitatif Aktivitas Antioksidan Ekstrak Etanol Propolis
Authors: Rosana Marilis , Ahwan Ahwan , Qonitah Fadilah 
Published: January 2022

ABSTRAKPropolis adalah zat yang terdiri dari campuran resin, serbuk sari dan lilin tanaman yang dikumpulkan oleh lebah madu. Selain itu propolis mengandung senyawa metabolit sekunder seperti flavonoid yang berpotensi sebagai antioksidan. Penelitian ini dilakukan dengan tujuan untuk mengetahui ada atau tidaknya potensi antioksidan dari ekstrak etanol propolis. Uji kualitatif aktivitas antioksidan ekstrak etanol propolis dilakukan menggunakan pereaksi DPPH (2.2-diphenyl-1-picrylhydrazyl). Hasil penelitian menunjukkan bahwa terjadi perubahan warna larutan DPPH dari unggu menjadi kuning pada ekstrak etanol propolis panen 6 bulan dan 1 tahun. Berdasarkan hasil tersebut dapat disimpulkan bahwa ekstrak etanol propolis panen 6 bulan dan 1 tahun memiliki potensi sebagai antioksidan. Kata kunci: Antioksidan; Propolis; DPPH.ABSTRACTPropolis is a substance consisting of a mixture of resin, pollen, and plant wax collected by honeybees. In addition, propolis contains secondary metabolite compounds such as flavonoids that have the potential as antioxidants. This research was conducted to know the potential or potential antioxidants of propolis ethanol extract. A qualitative test of antioxidant activity of propolis ethanol extract was conducted using DPPH reagents (2.2-diphenyl-1-picrylhydrazyl). The results showed that there was a discoloration of DPPH solution from Purple to yellow in propolis ethanol extract harvested 6 months and 1 year. Based on these results can be concluded that propolis ethanol extract harvest 6 months and 1 year has the potential as an antioxidant.Keyword: Antioxidant; Propolis; DPPH
Uji Aktivitas Antibakteri Staphylococcus Aureus Dan Escherichia Coli Terhadap Senyawa Sintesis Difeniltin (IV) Metil Ditiokarbamat
Authors: Sanuddin Mukhlis , Hadriyati Armini , Sari Indah Permata 
Published: January 2022

ABSTRAKSenyawa organotimah (IV) ditiokarbamat ini telah banyak digunakan dalam bidang farmasi dan kedokteran dan digunakan sebagai antibakteri, atikanker. dan sebagai antijamur. Senyawa. ini berhasil disintesis. dengan tujuan untuk mencari gambaran struktur. dan aktivitas antibakteri terhadap bakteri Staphylococcus aureus dan Escherichia coli. Senyawa ini disintesis dengan metode in situ yaitu dengan penambahan metil amina (0.02 mol) + karbon disulfida (0.02 mol) + logam difeniltin (IV) diklorida (0.01 mol), dan menghasilkan serbuk sebanyak 1.9 g dilakukan identifikasi menggunakan FTIR, 1H NMR, dan 13C NMR. Pengujian aktivitas antibakteri dilakukan dengan metode difusi kertas cakram dan menggunakan media NA (Nutrient Agar). Hasil penelitian dari senyawa sintesis menggunakan FTIR diperoleh gugus (C-N), (C-S), (C=N), (C=C), (C-H). Hasil pengukuran dari 1H NMR diperoleh δ 2,34 (CH3) dan δ 7.29 – 8,32 (aromatik). Hasil 13C NMR diperoleh δ 11.17 – 20.32 (CH3), δ 128.12 – 142.71 (C aromatik) dan δ 51.03 – 57.39 (CH2), dan hasil pengujian aktivitas antibakteri dengan konsentrasi 90 ppm dapat dikategorikan sangat kuat dalam aktivitas antibakteri. .Kesimpulan senyawa ini berhasil disintesis dan dikarakterisasi dengan gambaran struktur dan senyawa kompleks ini mempunyai aktivitas sebagai agen antibakteri. dengan kategori sangat kuat. Kata kunci : Antibakteri; FTIR; NMR; Organotimah (IV) ditiokarbamat.ABSTRACTThis organotin (IV) dithiocarbamate compound has been widely used in the pharmaceutical and medical fields and is used as an anticancer, antibacterial and antifungal. This compound was successfully synthesized with the aim of finding an overview of the structure and antibacterial activity against Staphylococcus aureus and Escherichia coli bacteria. This compound was synthesized by the in situ method by adding methyl amine (0.02 mol) + carbon disulfide (0.02 mol) + metal diphenyltin (IV) dichloride (0.01 mol), and producing a powder of 1.9 g was identified using FTIR, 1H NMR, and 13C NMR. Antibacterial activity testing was carried out using the paper disc diffusion method and using NA (Nutrient Agar) media. The results of the research of synthetic compounds using FTIR obtained groups (C-N), (C-S), (C=N), (C=C), (C-H). The measurement results of 1H NMR obtained 2.34 (CH3) and 7.29 – 8.32 (aromatic). The results of 13C NMR obtained 11.17 – 20.32 (CH3), 128.12 – 142.71 (C aromatic) and 51.03 – 57.39 (CH2), and the results of antibacterial activity test with a concentration of 90 ppm can be categorized as very strong in antibacterial activity. In conclusion, this compound was succesfully synthesized and caracterized by its structure description and this complex compound has activity as an antibacterial agent with a very strong category.Keywords : Antibacterial; FTIR; NMR; Organotimah (IV) ditiocarbamate.
PERPUSTAKAAN DIGITAL BUDAYA INDONESIA: PERAN MASYARAKAT DAN KOMUNITAS MELINDUNGI DAN MELESTARIKAN BUDAYA INDONESIA
Authors: Kusumaningtiyas Tiara , Nurazizah  
Published: January 2022

Indonesia is a country with cultural diversity, this diversity has not been able to be identified and registered, so it is feared those cultures will be eroded by globalization or claimed by another party. Perpustakaan Digital Budaya Indonesia with the concept of Virtual Community to collect data on culture which involves people and communities in the preservation of the culture of Indonesia. This article is going to describe how Perpustakaan Digital Budaya Indonesia through budaya-indonesia.org performs cultural preservation with the contribution of all elements of society. This study is using a qualitative approach with web observation and literature study as data collection techniques. The results showed that efforts to conserve the culture of the community by documenting the cultural records and inventory data, access and utilization of cultural data and the benefits of cultural data gathered at the Perpustakaan Digital Budaya Indonesia provide many benefits to Indonesia, among others present in various cultures, record various cultural heritages and minimize claims against Indonesian culture from foreign parties.
Erobots as research tools: Overcoming the ethical and methodological challenges of sexology
Authors: Dubé Simon , Santaguida Maria , Anctil Dave 
Published: January 2022

Sexology faces several ethical and methodological challenges. One of them is that sex researchers must rely on proxy methods to safely study fundamental aspects of human sexuality – in laboratories and natural environments. However, laboratory studies often lack ecological validity, whereas studies conducted in natural environments make it difficult for researchers to control experimental conditions or use sophisticated equipment. Together, this puts into question some of the empirical foundations of contemporary sexology. To address this problem, the present article proposes that sex researchers could leverage the potential of emerging technology, like erobots – or artificial erotic agents, such virtual partners, erotic chatbots, and sex robots – to help overcome some of the current ethical and methodological challenges of sexology. To make this case, this article describes these challenges; highlights how erobotic technologies could be employed as research tools to conduct more ecologically valid sexological studies safely and ethically in and outside laboratory settings; and discusses the relative strengths and weaknesses of embodied, virtual, and augmented erobots as experimental apparatus in sex research. Ultimately, this article concludes that the development of erobots that are useful for sexology may require further collaboration between academia and the private sector. It also concludes that the development of such useful erobots may allow us to gain a deeper understanding of ourselves and our eroticism.
The Strategy of Islamic Religious Education Teachers in Instilling Islamic Character During the Covid-19 Pandemic Period
Authors: Gusman Burhanudin Ata , Adi Kistoro Hanif Cahyo , Ru’iya Sutipyo 
Published: January 2022

The COVID-19 pandemic has had an impact on many aspects, one of which is the education aspect. Currently, the affective element is the main focus for educators. This study aims to determine the system, approach, and impact of the teacher's strategy. This research is qualitative research with a phenomenological approach. The research subjects were research informants, namely teachers, school principals, and ten students—methods of data collection using interviews with interview guide instruments prepared. This study found three crucial points: the system or strategy for planting the character of the teacher's approach and the impact of growing Islamic symbols. The process of Islamic religious education teachers in character building is through three ways, namely exemplary, advice and habituation. The positive impact that occurs is that students at MAN 4 Kebumen have implemented the planting of Islamic characters given by the teacher so that students experience changes in terms of nature such as behavior Changes include students helping each other, doing assignments on time, diligence in worship, accustomed to reading prayers, and eager to learn.
Keywords: Strategy; Islamic character; Example; Advice; Habit.
Islamic Worldview as The Basic of Islamic Society toward Society 5.0
Authors: Huringiin Nabila , Yasmin Alifah 
Published: January 2022

Society 5.0, the basic plan of science in the development of science and technology, the results of the previous 4 phases of reform; (Hunting), (Agricultural), (Industrial), and (Information). Until the fourth phase, the speed of knowledge is fast, but the flow of information is inadequate, social reforms arise, packaged into creative innovations to solve problems in parallel, grand design; IoT (Internet of Things), AI (Artificial Intelligence), and Big Data. Innovations that ensure the disappearance of regional disparities provide a wide range of service products. However, the problem has penetrated, because of the partial point of view, even though it has multidimensional aims. Islam runs in place, an ecological crisis, spiritual crisis, even moral crisis. This research is aimed at re-awakening that the development of science has existed for a long time. Through Islamic scientists, has been proven factually with worldview. The method used in this research is a qualitative literature method, researching literature data that is in accordance with the theme, both from journals, books, and related articles. By focusing the object of research on Muslim communities who tend to live in a generation of digital development. And from this research, it can be said that if the worldview of Islam is applied consistently, the following implications will be realized; First, changing the world-centered view to God-centered. Second; changing the materialism system into an integral method of thinking. Third; knowledge sourced from revelation is strengthened by reason and intuition. Fourth; composed of basic elements, and from them determine change, development, and progress.
Keywords: Islamic Worldview, Islamic Society, Society 5.0
Diagnosis of leprosy by PCR targeting gene encoding 36 kDa antigen of Mycobacterium leprae
Authors: Shampa Shaira Akter , Roy Chandon Kumar , Begam Mahfuja , Farzana Aleya , Hossain Kazi Manwar , Anwar Shaheda , Saleh Ahmed Abu 
Published: January 2022

Background & Objective: This cross sectional study was carried out to assess the diagnostic value of PCR in different forms of leprosy. For the detection of Mycobacterium leprae, DNA amplification by polymerase chain reaction of a 531-bp fragment of the Mycobacterium leprae specific gene encoding the 36 kDA antigen.
Methodology: It was done on different clinical specimens (slit smear of skin, ear lobule smear and nasal smear) from 50 leprosy patients attending the Leprosy Hospital, Mohakhali, Dhaka. Patients were divided into two groups; paucibacillary (70%) group and multibacillary (30%) group. PCR showed 100% positivity in skin and ear lobule and 73.4% positivity in nasal smear of multibacillary group. PCR was positive in 40%, 25.7% and 11.4% in skin lesion, ear lobule and nasal swab in paucibacillry group respectively.
Result: Compared with other diagnostic procedures, PCR showed clear advantages over both modified Z-N stain and auramine-phenol stain especially in paucibacillary patients.
Bangladesh J Med Microbiol 2020; 14 (1): 11-14
Colonization pattern of Gram positive organisms causing neonatal sepsis in pregnant women
Authors: Hasnat Hamima , Afroz Sadia , Islam Faijul , Hossain Mohammad Monir , Paul Shikha 
Published: January 2022

Background: Neonatal sepsis is one of the major causes of mortality and morbidity in neonates. Early onset neonatal sepsis (EONS) is commonly caused by mother’s vaginal and rectal organisms before or during the delivery process.
Objective: The aim of this study was to determine the colonization pattern of common gram positive organisms responsible for neonatal sepsis, in women of 35-37 weeks of pregnancy.
Methodology: A cross sectional analytical study was conducted from July 2018 to June 2019 at the department of Microbiology of Sir Salimullah Medical College, Dhaka. Total 107 of each vaginal and vaginorectal samples was collected from pregnant women at 35-37 weeks of pregnancy attending at the out-patient department of the Obstetrics and Gynaecology unit of Sir Salimullah Medical College & Mitford Hospital, Dhaka. Vaginal and vaginorectal samples were tested by standard culture technique using Todd– Hewitt broth, blood agar, High chrome UTI agar media. Data was collected by a questionnaire and results were analyzed by statistical package for the social sciences (SPSS) program.
Results: In this study, among 107 vaginal swab samples Staphylococcus aureus were the predominant isolate (51.40%), followed by Enterococci (20.56%), Coagulase negative Staphylococcus (14.95%) and Group B Sreptococcus (5.61%). Similarly among 107 vaginorectal swab samples commonest isolates were Staphylococcus aureus (56.1%), followed by Enterococci (52.34%), Coagulase negative Staphylococcus (11.21%) and Group B Streptococcus (6.54%).
Conclusion: The organisms from the vaginal and vaginorectal swabs were essentially the same. Staphylococcus aureus and Enterococci were the most abundant organisms that can cause neonatal sepsis, isolated from the vaginal and vaginorectal swab samples.
Bangladesh J Med Microbiol 2020; 14 (2): 12-18
Quality Assurance in the molecular diagnostic laboratory
Authors: Farook Saika , Siddiqui Tanvir Ahmed , Mondal Pritylata , Anwar Shaheda 
Published: January 2022

Molecular diagnostics is currently playing an imperative role in the clinical microbiology laboratory. Quality assurance and quality control issues have often remained underdeveloped in our country and are still critical. To relate patient results to these, molecular diagnostics carry values in clinical diagnosis, therapeutic drug monitoring and remission and those results need to be comparable across time and methods. This may be achieved either by producing the identical value across methods and test versions or by using reliable and stable reference materials in the medical laboratories engaged with molecular tests. The establishment of international standards and reference materials, assessment and maintenance of technical competencies, regulatory oversight and best practices considerations are thus of utmost importance. This review focuses on general and specific issues relevant for quality assurance and quality control in the routine molecular diagnostics laboratory.
Bangladesh J Med Microbiol 2021; 15 (1): 30-34
Aleitamento materno de prematuro: revisão integrativa de 2015 a 2020
Authors: Figueiredo Ana Carla Barbosa , Nascimento Marcia Helena Machado , Santos Valéria Regina Cavalcante dos , Soares Vanda Heloísa Marvão , Moraes Pilar Maria de Oliveira , Chermont Aurimery Gomes 
Published: January 2022

O contexto do aleitamento materno vivenciado por mães de recém-nascidos prematuros constitui a questão norteadora deste artigo, considerando as necessidades de crescimento, desenvolvimento neurológico, estabilidade clínica e controle da termorregulação para início da estimulação precoce da amamentação. Em contrapartida temos a condição sociocultural da mãe que necesita de apoio e orientações da equipe multiprofissional para travessia das situações advindas da internação de seu filho na unidade neonatal. Nesse caminho é indispensável propiciar a educação em saúde sobre a amamentação e os cuidados diários com o prematuro. Revisão integrativa da literatura sobre aleitamento materno em unidade neonatal no período de 2015 a 2020 realizada na Biblioteca Virtual em Saúde e bases de dados MEDLINE, LILACS e BDENF usandos os descritores em Ciências da Saúde (DeCS): aleitamento materno, recém-nascido prematuro, UTI neonatal; em seis etapas: elaboração da questão de revisão, busca dos artigos de acordo com critérios de inclusão e exclusão, coleta de dados, análise crítica dos artigos selecionados, discussão dos resultados e apresentação da revisão. Selecionados 148 artigos, destes 20 artigos compuseram a revisão. Nível de evidência dos artigos incluídos: 05 meta-análises - Nível I, 07 estudos transversais - Nível IV, 06 estudos qualitativos descritivos e 02 revisões integrativas - Nível V. As evidências descritas nos artigos analisados corroboram que o aleitamento materno aliado as tecnologias da saúde disponíveis aumentam a sobrevida dos prematuros. Políticas e estratégias de fortalecimento voltadas para o aleitamento materno de prematuros devem ser implementadas nas políticas públicas de saúde.
Atividades lúdico-educativas sobre Infecções Sexualmente Transmissíveis: uma proposta de Divulgação Científica no ambiente escolar
Authors: Martins Ariele da Silva , Silva Marcella Larrate da , Amaral Thamyris  Figueiredo do , Belo Mariana Soares da Silva Peixoto , Silva Bianca Ramos Marins , Costa Patricia Cristina dos Santos 
Published: January 2022

Divulgação Científica (DC) é um método de difusão do conhecimento científico-acadêmico cujo objetivo é democratizar o acesso à informação e estimular o desenvolvimento de senso crítico, atingindo diferentes públicos. A utilização de práticas lúdico-educativas como método de divulgação faz-se necessária para um aprendizado mais dinâmico e com maior desenvolvimento cognitivo. Reforça ainda as instituições de ensino como importantes promotoras de ações educativas, especialmente em saúde. Sabendo que os adolescentes estão entre os grupos mais vulneráveis e possuem defasagem de conhecimento básico quanto às Infecções Sexualmente Transmissíveis (IST), a adoção de intervenções mais efetivas acerca do tema é crucial. Assim, com esse trabalho, objetiva-se propor estratégias de DC em espaços escolares através de atividades lúdico-educativas sobre IST como ferramenta pedagógica e promotora da saúde. Esta proposta de divulgação científica é composta por estratégias de ensino, diferentes do modelo expositivo tradicional, tais como a promoção de conhecimento por meio de informações básicas e preventivas sobre essas infecções e seus impactos na saúde; ações interativas através de jogos de perguntas e respostas intitulados “Jogo de Tabuleiro Humano”, “Quiz Torta na Cara” e “Ida ao Posto de Saúde”; e divulgação das unidades locais de Atenção Primária à Saúde. Essas atividades lúdicas são relevantes por estimularem a participação e trabalho em equipe dos estudantes envolvidos, além de favorecerem ao processo de ensino-aprendizagem mais atrativo e criativo, questões fundamentais para a prática de ações promotoras da saúde no ambiente escolar.
Metaplasia e lesões histopatológicas de mucosa esofágica
Authors: Moura Elomar Rezende , Souza Gabrielle Barbosa Vasconcelos de , Trindade Yasmin Tourinho Delmondes , Santana Neto Durval José de , Moreira Larissa Gonçalves , Silva Wianne Santos , Barreto Íkaro Daniel de Carvalho , Silva Décio Fragata da , Meurer Luíse , Trindade Leda Maria Delmondes Freitas 
Published: January 2022

A metaplasia é um processo adaptativo reversível, que acontece em um tipo de célula que, mediante um estímulo, passa pela substituição de outro tipo celular de linhagem semelhante. Objetivo: identificar a prevalência de metaplasia e a sua relação com lesões histopatológicas encontradas em amostras de mucosa esofágica. Método: estudo transversal, retrospectivo com uma amostra de 1953 laudos histopatológicos de mucosa esofágica. Resultados: de 1953 laudos, 548 (28,1%) tinham metaplasia, sendo 94 (17,1%) do tipo intestinal e destes 35(6,4%) focal; 133(6,8%) tinham esôfago de Barrett, 414 (75,5%) com ectopia gástrica, 21 (1,1%) com displasia, sendo 12 (57,1%) de baixo grau e 9 (42,9%) alto grau e 1427 (73,1%) laudos apresentaram esofagite. A faixa etária mediana dos portadores de metaplasia foi de 45 anos (IIQ 34-55), sendo 289 (51,7%) do sexo feminino e 438 (81,4%) procedentes da capital. Dos laudos com metaplasia, 46 (8,2%) tinham Helicobacter pylori, 30 (5,3%) esôfago de Barrett e 14 (2,6%) com atrofia gástrica associada a bactéria, entretanto não houve associação significativa com a H.pylori. Foi estatisticamente significativo (p<0,001) a associação de metaplasia com esofagite, esofagite eosinofílica e pólipo adenomatoso. Conjuntamente, observamos um menor risco de metaplasia na presença de esofagite (RR: 0,44; IC95%: 0,36-0,55) e maior na presença de Eosinófilos >=15 eos/ CGA (RR: 3,27; IC95%: 1,70-6,62). Conclusão: Não temos evidências de relação entre metaplasia no esófago e H.pylori. A ausência de esofagite e a presença de Eosinófilos >=15 eos/ CGA está associado a um maior risco de transformação metaplásica.
Introducing Nafion for In Situ Desalting and Biofluid Profiling in Spray Mass Spectrometry
Authors: Song Xiaowei , Mofidfar Mohammad , Zare Richard N. 
Published: January 2022

We introduce Nafion into the ambient ionization technique of spray mass spectrometry to serve for in situ desalting and direct analysis of biological fluids. Nafion was coated onto the surface of the triangular spray tip as the cation exchange material. Because the sulfonic group from the Nafion membrane effectively exchanges their carried protons with inorganic salt ions (e.g., Na+ and K+), the analyte’s ionization efficiency can be significantly enhanced by reducing ion suppression. The desalting efficiency can reach 90% and the maximum tolerance of the absolute salt amount reaches 100 μmol. The mass spectral profile can also be simplified by removing the multiple adducted ion types from small-molecule drugs and metabolites ([M + Na]+ and [M + K]+), or multiply charged ions formed by proteins ([M + nNa]n+ and [M + nK]n+). Thus, the Nafion coating makes less ambiguous data interpretation collected from spray mass spectrometry for qualitative profiling or quantitative measurement of a target analyte.