bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhanced Electrochemiluminescence of Porphyrin‐Based Hydrogen‐Bonded Organic Frameworks at Low Positive Potential via Substituent‐Induced Outer‐Sphere Microenvironment Modulation
Authors: Cui Lin , Yang Yuncong , Song Linlin , Cao Xueting , Chu Wenqi , Zhang Chun‐yang 
Published: February 2025

AbstractThe porphyrin‐based hydrogen‐bonded organic framework (HOF) offers a superior platform for decoding electrochemiluminescence (ECL) via controlling charge transfer due to its higher solubility, chemical stability, and tunable framework behavior. In this research, three kinds of HOFs including TDPP‐HOF, TCPP‐HOF, and TCNPP‐HOF are synthesized based on a porphyrin tectonic plate decorated with 2,4‐diaminotriazinyl (DAT), carboxyl, and nitrile moieties to study their ECL performances. The hydrazine as the coreactant can trigger TDPP‐HOF at the low‐excited positive potential to generate 15.8‐ and 112.9‐fold enhancement in ECL signal than TCNPP‐HOF and TCPP‐HOF. Experimental results and density functional theory calculations verify that TDPP‐HOF with a lower bandgap and a larger binding energy (ΔE) between coreactant and HOF is beneficial to intrareticular charge transfer (ICT), facilitating the enhancement of ECL performance. These results indicate that the peripheral substituents can establish a specialized outer‐sphere microenvironment around the porphyrin center to tune both the HOF activity and the ECL performance. As a proof of concept, a simple TDPP‐HOF‐based ECL sensor is constructed to sensitively detect phenolic compounds. This research provides a new avenue for improving the ECL performance via modulating the outer‐sphere microenvironment of HOFs.
A Hyperstable Aqueous Zinc‐Ion Battery Based on Mo1.74CTz MXene
Authors: Chen Ningjun , Ronchi Rodrigo , Halim Joseph , Persson Per O. Å. , Qin Leiqiang , Rosen Johanna 
Published: February 2025

AbstractThe sustainable utilization of natural resources and growing demand for various electronic devices have promoted the development of safe, stable, and rechargeable aqueous zinc‐ion batteries (AZIBs). However, a stable cathode material is crucial for ZIBs in an aqueous electrolyte, since it is more difficult for divalent Zn2+ to be reversibly inserted and extracted between active materials than it is for monovalent metal ions. In this work, a tailored multi‐defect MXene, Mo1.74CTz, of a complete chemical formula of Mo1.74±0.06CO0.95±0.02(OH)0.63±0.01F0.3±0.03.0.2±0.05H2Oads (Mo1.74CTz), is assembled as cathode in AZIBs. It achieved 75% capacity retention and nearly 100% Coulombic efficiency even after up to 100 000 cycles as the intrinsic structural stability and many vertical holes of the Mo1.74CTz MXene contributed to alleviating the MXene collapse under repeated charge and discharge. Meanwhile, the Mo1.74CTz‐based AZIBs exhibited good performance with a specific capacity of 200 mAh g−1 at a current density of 0.2 A g−1, which greatly exceeds previous reports of pure MXene‐based cathodes in AZIBs. This work will aid in finding new solutions for sustainable energy development, which will pave the way for AZIBs as an alternative to lithium‐ion batteries (LIBs) in the future.
Tannic Acid Modified Epoxidized Natural Rubber Based High Performing Triboelectric Nanogenerator
Authors: Guchait Aparna , Haridas C. P. Ajay , Chattopadhyay Santanu , Mondal Titash 
Published: February 2025

AbstractConsidering today's environmental concerns, the development of triboelectric nanogenerator (TENG) is gaining immense interest as a green energy harvesting technology. However, most materials leveraged in TENG construction are based on non‐renewable resources. Therefore, developing a bio‐based composite with high performance for the TENG application is extremely desirable. This study uses Tannic acid (TA), a naturally occurring polyphenolic compound, as a reactive bio‐filler in the bio‐based elastomer Epoxidized natural rubber (ENR‐50). This bio‐composite is utilized as a tribo‐positive pair for TENG construction, which resulted in a very high output voltage of 751 V (at 9 Hz) and 568 V (at 5 Hz). The maximum obtained power density recorded at 9 Hz is 37 W m−2 at 1 MΩ external load resistance and an average power density is 20 W m−2 at a load resistance of 10–100 MΩ. This excellent output performance results from the high electron‐donating ability of TA. It is many‐fold higher in terms of power density than recently reported all the bio‐composites. Density Functional Theory is leveraged to probe contact electrification process. The result correlates with surface energy, dielectric, dynamic mechanical properties, and surface morphologies (roughness). Notably that such a bio‐composite can be a promising material for next‐generation power harvesting technology.
Next‐Generation Chemiresistive Wearable Breath Sensors for Non‐Invasive Healthcare Monitoring: Advances in Composite and Hybrid Materials
Authors: Verma Gulshan , Gupta Ankur 
Published: February 2025

AbstractRecently wearable breath sensors have received significant attention in personalized healthcare systems by offering new methods for remote, non‐invasive, and continuous monitoring of various health indicators from breath samples without disrupting daily routines. The rising demand for rapid, personalized diagnostics has sparked concerns over electronic waste from short‐lived silicon‐based devices. To address this issue, the development of flexible and wearable sensors for breath sensing applications is a promising approach. Research highlights the development of different flexible, wearable sensors operating with different operating principles, such as chemiresistive sensors to detect specific target analytes due to their simple design, high sensitivity, selectivity, and reliability. Further, focusing on the non‐invasive detection of biomarkers through exhaled breath, chemiresistive wearable sensors offer a comprehensive and environmentally friendly solution. This article presents a comprehensive discussion of the recent advancement in chemiresistive wearable breath sensors for the non‐invasive detection of breath biomarkers. The article further emphasizes the intricate development and functioning of the sensor, including the selection criteria for both the flexible substrate and advanced functional materials, including their sensing mechanisms. The review then explores the potential applications of wearable gas sensing systems with specific disease detection, with modern challenges associated with non‐invasive breath sensors.
Advancements and Perspectives on Nonaqueous Electrolyte Engineering for Graphite Anode in Potassium‐Ion Battery
Authors: Mao Zhifei , Wang Keliang , Fan Qi Hua , Wang Ruigang 
Published: February 2025

AbstractPotassium‐ion batteries (KIBs) have emerged as a promising alternative to lithium‐ion batteries due to the abundance and low cost of potassium resources. Coupled with commercial graphite anode, KIBs have great potential for the next‐generation large‐scale electrochemical energy storage devices. However, graphite anode in KIBs suffers from rapid capacity decay in commercial “potassium hexafluorophosphate (KPF6) + ethylene carbonate (EC)” electrolytes. These issues can be addressed through electrolyte engineering, which has been proven effective in improving graphite performance. This review explores the underlying mechanisms of K+ storage in graphite, the challenges of electrolyte design, and the recent advancements in electrolyte engineering for graphite anode optimization in KIBs.
Liposome‐Enabled Nanomaterials for Muscle Regeneration
Authors: Wu Shuang , Lu Jianqin 
Published: February 2025

AbstractMuscle regeneration is a vital biological process that is crucial for maintaining muscle function and integrity, particularly for the treatment of muscle diseases such as sarcopenia and muscular dystrophy. Generally, muscular tissues can self‐repair and regenerate under various conditions, including acute or chronic injuries, aging, and genetic mutation. However, regeneration becomes challenging beyond a certain threshold, particularly in severe muscle injuries or progressive diseases. In recent years, liposome‐based nanotechnologies have shown potential as promising therapeutic strategies for muscle regeneration. Liposomes offer an adaptable platform for targeted drug delivery due to their cell membrane‐like structure and excellent biocompatibility. They can enhance drug solubility, stability, and targeted delivery while minimizing systemic side effects by different mechanisms. This review summarizes recent advancements, discusses current applications and mechanisms, and highlights challenges and future directions for possible clinical translation of liposome‐based nanomaterials in the treatment of muscle diseases. It is hoped this review offers new insights into the development of liposome‐enabled nanomedicine to address current limitations.
A Systems Thinking Approach to Understand the Impacts of Pesticides on the Great Barrier Reef Ecosystems
Authors: Phan Thuc D. , Bertone Edoardo , Neelamraju Catherine , Nguyen Nam , Nguyen Tien Q. , Pham Tuyen V. 
Published: February 2025

ABSTRACTThe health and resilience of the Great Barrier Reef ecosystems are affected by complex dynamics and interconnected processes. A systems thinking approach can aid to comprehensively understand the past, current and future system behaviour, thereby informing effective decision‐making. A qualitative conceptual model was developed based on the theory of systems thinking approach and critical literature reviews, giving consideration to the complex non‐linear feedbacks that determine the structure and behaviour of the system. The model indicates that the feedback structure of the system is governed by agricultural production, pesticide applications, pesticide residues, water quality improvement policies and climate change. The findings highlight the inherent challenges of achieving water quality goals in a complex and dynamic environment, constantly influenced by many factors (e.g., climate change). This underscores the critical need for ongoing research, adaptation and a shift towards a systems perspective, enabling decision makers to avoid the unintended consequences emerging from linear thinking, thereby initiating more flexible and adaptive management strategies for saving this iconic system.
Von Amstetten zur Molekulardynamik – Teil 1
Authors: Lang Robert , Ladinek Markus 
Published: February 2025

AbstractIm Jahr 1875 fand in Österreich die Entgleisung der Lokomotive Amstetten statt. Die Ursache war ein Radreifenbruch durch eine damals noch kaum beachtete Werkstoffeigenschaft – die Werkstoffermüdung. Zum 150. Jahrestag sollen im ersten Teil in einem Abriss einige wichtige geschichtsträchtige Ereignisse in der Forschungsgeschichte der Ermüdungsfestigkeit beleuchtet werden. Dabei werden Einflussfaktoren untersucht sowie diskutiert und es wird auf den heutigen Stand der Technik verwiesen. Dieser Abriss kann nicht vollständig sein und soll es auch gar nicht. So mancher heutige Aspekt oder heutiges Konzept wird aber erst im historischen Kontext plausibel und nachvollziehbar. Im zweiten Teil dieses Beitrags wird ein Blick auf den Stand der Wissenschaft gewagt. Skalenmodelle und molekulardynamische Ansätze sollen angerissen und aufgezeigt werden. Zuletzt wird ein Fazit über 150 Jahre gezogen. Warum sind diese modernen Aspekte in der Praxis kaum vertreten und wo ist eine Lösung im Spannungsfeld zwischen bewährten und modernen Methoden erkennbar, welche die Forschung wieder näher an die Praxis bindet.
Von Amstetten zur Molekulardynamik – Teil 2
Authors: Ladinek Markus , Lang Robert 
Published: February 2025

AbstractIm Jahr 1875 fand in Österreich die Entgleisung der Lokomotive Amstetten statt. Die Ursache war ein Radreifenbruch durch eine damals noch kaum beachtete Werkstoffeigenschaft – die Ermüdungsfestigkeit. Im ersten Teil dieses Zweiteilers wurde die Forschungsgeschichte in einigen Aspekten der Ermüdungsfestigkeit beleuchtet. Im zweiten Teil dieses Beitrags richtet sich der Blick auf den Stand der Wissenschaft. Fortschrittliche Methoden werden vorgestellt, die viele gewachsene Probleme zu lösen scheinen. Dennoch bleiben diese Methoden aus vielerlei Gründen der Wissenschaft vorbehalten und finden praktisch keinen Einzug in die Praxis – trotz der evidenten Vorteile. Die Gründe scheinen vielfältig und doch überbrückbar, wie Vorzeigebeispiele veranschaulichen.
Morphology and molecules revealed a remarkable new genus of Lamiaceae, a surprising discovery in south‐eastern Europe
Authors: Surina Boštjan , Vuksanović Snežana , Dragićević Snežana , Glasnović Peter , Siljak‐Yakovlev Sonja , Balant Manica , Radosavljević Ivan , Xiang Chun‐Lei , Li Bo 
Published: February 2025

AbstractPetrolamium crnojevicii gen. & sp. nov., a new distinct and remarkable monotypic genus of Lamiaceae, was discovered in the Dinaric karst of southern Montenegro. This taxon exhibits a unique combination of morphological traits, including eglandular, mostly glabrous reniform leaves with 5–7 lobes and prominent hydatodes at their tips. Its small pedicellate flowers feature included anthers and styles within the corolla tube, a straight, narrow, and emarginate to bifurcate posterior corolla lip, and an anterior lip with entire, broadly elliptic‐oblong lateral lobes. The trigonous mericarps have a truncated apex and bear fatty tissue. Notably, Petrolamium has a unique chromosome number of 2n = 32. A molecular phylogenetic analysis, based on 79 plastid protein‐coding genes and 5 chloroplast markers placed Petrolamium in the subfamily Lamioideae, where it forms a distinct lineage, sister to the other members of the tribe Lamieae. Petrolamium is also unique from an ecological point of view, as it exclusively inhabits floristically depauperate calcareous rock crevices in a very restricted distribution range. This makes P. crnojevicii a critically endangered species according to IUCN criteria and emphasizes the need for immediate conservation efforts. This study highlights the importance of ongoing floristic exploration, demonstrating that even in regions long considered botanically well‐known, important discoveries can still emerge, including within extensively investigated plant families like the Lamiaceae.
Thriving in Adversity: Yeasts in the Agave Fermentation Environment
Authors: Colón‐González Maritrini , Aguirre‐Dugua Xitlali , Guerrero‐Osornio Mariana G. , Avelar‐Rivas J. Abraham , DeLuna Alexander , Mancera Eugenio , Morales Lucia 
Published: February 2025

ABSTRACTAgave spirits have gained global recognition and hold a central position within the cultural heritage of Mexico. Traditional distilleries, characterized by open fermentations driven by local microbial communities, persist despite the rise of industrial‐scale counterparts. In this review, we explore the environmental conditions and production practices that make the must of cooked agave stems a unique habitat for colonizing microorganisms. Additionally, we review selected studies that have characterized yeast species within these communities, with a focus on their metabolic traits and genomic features. Over 50 fungal species, predominantly Saccharomycetales and few Basidiomycetes, along with a similar number of lactic and acetic acid bacteria, have been identified. Despite variations in the chemical composition of the agave substrates and diversity of cultural practices associated with each traditional fermentation process, yeast species such as Saccharomyces cerevisiae, Kluyveromyces marxianus, Torulaspora delbrueckii, and several Pichia species have been consistently isolated across all agave spirit‐producing regions. Importantly, cooked agave must is rich in fermentable sugars, yet it also contains inhibitory compounds that influence the proliferation dynamics of the microbial community. We discuss some of the genetic traits that may enable yeasts to flourish in this challenging environment and how human practices may shape microbial diversity by promoting the selection of microbes that are well‐adapted to agave fermentation environments. The increasing demand for agave spirits, combined with concerns about the preservation of natural resources and cultural practices associated with their production, underscores the need to deepen our understanding of all key players, including the yeast communities involved.
Impact of education in patients undergoing physiotherapy for lower back pain: a level I systematic review and meta-analysis
Authors: Migliorini Filippo , Maffulli Nicola , Schäfer Luise , Manocchio Nicola , Bossa Michela , Foti Calogero , Betsch Marcel , Kubach Joshua 
Published: February 2025

Abstract

Introduction
Lower back pain (LBP) is one of the most common musculoskeletal disorders in modern society, with a lifetime incidence of up to 90%. According to most national and international guidelines, educational interventions play a central role in the multimodal treatment of LBP. This systematic review and meta-analysis investigated the impact of educational interventions on pain and disability in patients with LBP undergoing physiotherapy compared to patients without educational interventions undergoing physiotherapy.

Methods
In October 2024, a comprehensive computer-aided search was performed to assess the online databases PubMed, Web of Science, Google Scholar, and Embase. The search followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria with an established PICOTD algorithm. Two authors independently performed the data extraction and risk of bias evaluation. The primary outcome measures extracted were a pain score (VAS or NRS) and the Roland Morris Disability Questionnaire (RMQ).

Results
Data from 8152 patients were retrieved. The mean length of follow-up was 6.2 ± 3.9 months, the mean length of symptom duration was 66.7 ± 51.6 months, and the mean age of the patients was 46.7 ± 9.2 years. Compared to physiotherapy alone, additional education did not reduce pain (P = 0.4) or disability according to the RMQ (P = 0.9).

Conclusion
The addition of education did not impact pain and disability in patients undergoing physiotherapy for chronic non-specific LPB.

Level of evidence
Level I, systematic review and meta-analysis of RCTs.
Focus on hydrochars produced from hydrothermal liquefaction of beech wood, soda lignin and black liquor
Authors: Wörner Maximilian , Hornung Ursel , Karagöz Selhan , Zevaco Thomas , Dahmen Nicolaus 
Published: February 2025

Abstract
Previous studies on the hydrothermal liquefaction (HTL) of biomass have primarily focused on bio-oil production, overlooking the significant hydrochar by-product. In this work, the HTL of beech wood, soda lignin, and black liquor was performed at temperatures of 300 °C and 350 °C for 20 min. The effect of temperature and biomass type on hydrochar yields and properties was thoroughly investigated. The mass yields of the hydrochars varied between 25.92 wt% and 32.70 wt%. An increase in temperature from 300 °C to 350 °C led to a decrease in hydrochar mass yields. The carbon yield was found to be highest (51 wt%) at 300 °C using beech wood. The highest heating value, 30.97 MJ/kg, was obtained with hydrochar derived from soda lignin at 300 °C. Solid-state carbon NMR demonstrated that the hydrochars derived from black liquor contain condensed aromatic structures. Both the type of biomass and temperature significantly influenced the characteristics of the resulting hydrochar. This research demonstrates that hydrochar holds promise as a solid biofuel due to its advantageous energy content and carbon yield, highlighting its potential for sustainable energy applications.
Islet autoantibodies in Thai individuals individuals diagnosed with type 1 diabetes before 30 years of age: a large multicentre nationwide study
Authors: Plengvidhya Nattachet , Suthon Sarocha , Nakdontri Tassanee , Teerawattanapong Nipaporn , Ingnang Saranya , Tangjittipokin Watip ,   Thai Type 1 Diabetes and Diabetes Diagnosed Before Age 30 Years Registry, Care, and Network (T1DDAR CN)
Published: February 2025

Abstract

Aims/hypothesis
Type 1 diabetes is categorised into autoantibody positive and autoantibody negative. Most type 1 diabetes research has focused on European populations, leaving a gap in understanding in relation to other ethnic groups, including Thai populations. This lack of data is significant given Thailand’s poor prevention and therapeutic management strategies. We aimed to investigate the frequency and distribution of islet autoantibodies among Thai individuals with long-standing type 1 diabetes diagnosed before the age of 30 years.

Methods
We conducted a nationwide population-based study involving 48 hospitals in Thailand from May 2020 to September 2023, enrolling 953 participants. Demographic and clinical characteristics of individuals with autoantibody-positive and -negative type 1 diabetes were analysed. The autoantibodies GAD65, IA-2 and ZnT8 were measured using ELISA. A random C-peptide level was detected by electrochemiluminescence immunoassay.

Results
Thai individuals with autoantibody-negative type 1 diabetes comprised 34.2% of the population. Among all individuals, the frequency of GAD65, IA-2 and ZnT8 was 56%, 37% and 33%, respectively. Autoantibody-negative individuals with type 1 diabetes were older at diagnosis, had higher BMI and had higher random C-peptide levels compared with autoantibody-positive individuals with type 1 diabetes. Female individuals had a higher prevalence of type 1 diabetes than male individuals (58% vs 42%; p=1.531 × 10−5). The southern region of Thailand exhibited a distinct pattern of autoantibody frequency compared with other regions (p=0.0001561).

Conclusions/interpretation
The frequency, distribution and characteristics of autoantibody-positive and -negative long-standing type 1 diabetes in Thailand showed uniqueness from other populations. This provides insight into the disease that may have implications for type 1 diabetes prediction, treatment and pathogenesis, especially in the Southeast Asian population.

Graphical Abstract