bluuebunny/crossref_metadata_2025_split huggingface dataset:
Paper 2: a systematic review of narrative therapy treatment outcomes for eating disorders—bridging the divide between practice-based evidence and evidence-based practice
Authors: Conti Janet , Heywood Lauren , Hay Phillipa , Shrestha Rebecca Makaju , Perich Tania 
Published: September 2022

Abstract
Background
Narrative therapy has been proposed to have practice-based evidence however little is known about its research evidence-base in the treatment of eating disorders. The aim of this study was to conduct a systematic review of the outcome literature of narrative therapy for eating disorders.

Method
Treatment outcome data were extracted from 33 eligible included studies following systematic search of five data bases. The study is reported according to Preferred Reporting items for Systematic Reviews and Meta-Analyses guidelines.

Results
Of the identified 33 studies, 3 reported positive outcomes using psychometric instruments, albeit some were outdated. Otherwise, reported outcomes were based on therapy transcript material and therapist reports. The most commonly reported treatment outcome was in relation to shifts in identity narratives and improved personal agency with a trend towards under-reporting shifts in ED symptoms. Some improvements were reported in interpersonal and occupational engagement, reduced ED symptoms, and improved quality of life, however, there was an absence of standardized measures to support these reports.

Conclusions
This systematic review found limited support for narrative therapy in the treatment of eating disorders through practice-based evidence in clinician reports and transcripts of therapy sessions. Less is known about systematic treatment outcomes of narrative therapy. There is a need to fill this gap to understand the effectiveness of narrative therapy in the treatment of EDs through systematic (1) Deliveries of this intervention; and (2) Reporting of outcomes. In doing so, the research arm of narrative therapy evidence base will become more comprehensively known.
Nutritional Modulation of Sleep Latency, Duration, and Efficiency: A Randomized, Repeated-Measures, Double-Blind Deception Study
Authors: LANGAN-EVANS CARL , HEARRIS MARK A. , GALLAGHER CHLOE , LONG STEPHEN , THOMAS CRAIG , MOSS ANDREW D. , CHEUNG WILLIAM , HOWATSON GLYN , MORTON JAMES P. 
Published: September 2022

ABSTRACT

Purpose
This study aimed to test the hypothesis that a novel nutritional blend composed of tryptophan, glycine, magnesium, tart cherry powder, and l-theanine enhances subjective and objective measures of sleep during free living conditions.

Methods
In a randomized, repeated-measures crossover and double-blind deception design, participants (n = 9 males and 7 females, age = 24 ± 3 yr, body mass = 69.8 ± 11.6 kg, stature = 170.8 ± 9.1 cm) completed a 3-d familiarization period, followed by 3-d intervention and placebo trials. Subjective Pittsburgh Quality Sleep Index, Core Consensus Sleep Diary, and Karolinska Sleepiness Scale survey tools, alongside objective actigraphy measures of sleep, were assessed, with daily nutritional intake, activity, and light exposure standardized between trials. Participants provided daily urine samples for assessment of targeted and untargeted metabolomes.

Results
The intervention trial reduced sleep onset latency (−24 ± 25 min; P = 0.002), increased total sleep time (22 ± 32 min; P = 0.01), and increased sleep efficiency (2.4% ± 3.9%; P = 0.03), while also reducing morning sleepiness (P = 0.02). Throughout the study, 75% of participants remained blinded to sleep assessment as a primary outcome measure, with 56% subjectively indicating improved sleep during the intervention trial. Metabolomic analysis highlighted several significantly altered metabolomes related to sleep regulation between trials, inclusive of 6-sulfatoxymelatonin, d-serine, and l-glutamic acid.

Conclusions
Data demonstrate that using the proposed blend of novel nutritional ingredients during free living conditions reduced sleep onset latency, increased total sleep duration, and increased sleep efficiency, leading to reduced perceptions of morning sleepiness. These effects may be mediated by the upregulation of key metabolites involved in the neurophysiological modulation of the sleep/wake cycle.
Evaluation of assisted reproductive technology treatment outcomes based on stimulation dosages and anti-Mullerian hormone levels
Authors: Pannu Navdeep Singh , Samsudin Nurulhafizah , Ye Lo Jia , Tian Tee Sze 
Published: September 2022

Background: Serum levels of anti-Müllerian hormone (AMH) have a significant association with ovarian response in the event of assisted reproductive technology (ART) treatment cycles. The present study was performed to evaluate the ovarian stimulation protocols selection with respect to serum AMH levels in patients and its impact on ART outcome. Methods: Based on the serum AMH, 191 women were classified as low, normal and high responders. Follicle Stimulating Hormone (FSH) and Human Menopausal Gonadotropin (HMG) dosages in controlled ovarian stimulation were determined. Retrieval, maturation, fertilization and utilization rates were measured. Subgroup analysis was done using one-way ANOVA followed by post hoc analysis. The relationship between AMH levels and fertilization was determined using Pearson’s correlation analysis. A p-value <0.05 was considered as statistically significant. Results: According to AMH levels, the majority of the patients were normal responders (52.4%) followed by high responders (29.8%) and low responders (17.8%). The average FSH, HMG per day and number of days HMG required was found to be significant among the different responders. Further, retrieval rate and blastulation rate was found to be significant among the different responders. A positive correlation was found between AMH and the number of oocytes retrieved and number of oocytes successfully fertilized, which was found to be significant. In addition, there was a significant inverse relationship between AMH levels and age. Conclusions: The study outcomes revealed that the rates of retrieval, maturation, fertilization, embryo utilization and blastulation were higher among the high responders compared with the low responders. Thus, proper increase in dosages of ovarian stimulation protocol is required among the low responders to achieve quality embryos.
Prevalence of leakage and its negative impact on quality of life in people living with a stoma in the UK
Authors: Osborne Wendy , White Maddie , Aibibula Miriayi , Boisen Esben Bo , Ainsworth Rachel , Vestergaard Martin 
Published: September 2022

Background: People with a stoma are reported to experience leakage, which negatively impacts patient quality of life (QoL). Aim: To assess the impact of leakage experienced by individuals with a stoma in the UK. Methods: Data were analysed from 301 patients living in the UK who completed a questionnaire concerning the physical and psychosocial impact of living with a stoma. Findings: Most respondents had had their stoma for more than 5 years. Nine out of 10 worried about leakage to varying degrees and half the respondents accepted that this was a worry they had to live with. Almost 70% experienced leakage onto clothes within the preceding year, and 28% experienced this monthly. Peristomal skin complications were experienced by 82% of respondents, the severity of which correlated with reductions in QoL. Conclusion: Despite the consequential negative impact of leakage on QoL, individuals are not seeking advice to resolve leakage-related issues, including from their specialist stoma care nurse.
Multi-gigahertz mode-locked femtosecond Yb:KLuW waveguide lasers
Authors: Bae Ji Eun , Mateos Xavier , Aguiló Magdalena , Díaz Francesc , Ajates Javier García , Romero Carolina , Vázquez de Aldana Javier Rodríguez , Rotermund Fabian 
Published: September 2022

We demonstrate multi-gigahertz continuous-wave mode-locking of a Yb:KLuW waveguide laser. A femtosecond-laser-inscribed Yb:KLuW channel waveguide in an extended laser cavity delivers a fundamentally mode-locked laser near 1030 nm. A tunable few-centimeter-long cavity containing a single-walled carbon nanotube saturable absorber as mode-locker generates self-starting femtosecond pulses with average output powers exceeding 210 mW at repetition rates of 2.27, 2.69, and 3.55 GHz. The laser cavity, which includes a wedged waveguide, is extended by using a lens pair that controls the laser fluence on the saturable absorber for reliable mode-locked operation without instability. The presented laser performance, mode-locked up to 3.55 GHz, highly suggests the potential of crystalline Yb:KLuW waveguides for realizing high-power ultrafast lasers with higher GHz repetition rates in a quasi-monolithic cavity.
Sodium-glucose cotransporter 2 (SGLT2) inhibitor initiation and hepatocellular carcinoma prognosis
Authors: Hendryx Michael , Dong Yi , Ndeke Jonas M. , Luo Juhua 
Published: September 2022

IntroductionSodium-glucose cotransporter 2 (SGLT2) inhibitors are a relatively new class of antidiabetic drugs. Emerging findings from laboratory studies indicate that SGLT2 inhibitors can improve liver function and suppress the proliferation of hepatocellular carcinoma (HCC) cells. The aim of this study was to test the hypothesis that initiation of SGLT2 inhibitors improves HCC prognosis in a human population.MethodsWe used National Surveillance, Epidemiology and End Results (SEER)—Medicare linked data in the United States to evaluate the role of SGLT2 inhibitor initiation on the survival of HCC patients. 3,185 HCC patients newly diagnosed between 2014 and 2017 aged 66 years or older with pre-existing type 2 diabetes were included and followed to the end of 2019. Information on SGLT2 inhibitor initiation was extracted from the Medicare Part D file.ResultsSGLT2 inhibitor initiation was associated with significantly lower mortality risk after adjusting for potential confounders (HR = 0.68, 95% CI = 0.54–0.86) with stronger association for longer duration of use (HR = 0.60, 95% CI = 0.41–0.88). Further, we found that SGLT2 inhibitor initiation was associated with a lower risk mortality risk ranging from 14% to 60% regardless of patient demographic variables, tumor characteristics, and cancer treatments.ConclusionOur large SEER-Medicare linked data study indicates that SGLT2 inhibitor initiation was associated with improved overall survival of HCC patients with pre-existing type 2 diabetes compared with no SGLT2 inhibitor use. Further studies are needed to confirm our findings and elucidate the possible mechanisms behind the association.
Effect of Different Sintering Cycles on the Flexural Strength of Full Contour Monolithic Zirconia – An In-Vitro Comparative Study
Authors: Sanath Kumar Shetty  , Feba Maria Varghese  , Mohammed Zahid  , Kevin Fernandes  , Fahad Mohammad  , Prakyath Malli  
Published: September 2022

BACKGROUND
Monolithic zirconia restorations are known to exhibit good mechanical properties and acceptable aesthetics. During the fabrication of zirconia prostheses, the sintering process is the most critical step which determines the performance of the final product. However, a lot of issues with zirconia restorations were related to sintering cycles which can affect the crystalline content and grain growth that can affect its mechanical properties. The purpose of this study was to evaluate and compare the effect of different sintering cycles on the flexural strength of full-contour monolithic zirconia.
METHODS
In this in-vitro study, a total of 44 bar-shaped zirconia samples (Amann Girrbach Ceramill® CAD/CAM Material – ZOLID HT+) of final dimensions 20 x 4 x 2 mm were fabricated using Amann Girrbach Ceramill mind – computer-aided designing software and Amann Girrbach Ceramill® motion2 – computer-aided milling unit. These samples were randomly allocated into four groups with 11 samples in each group namely, Group 1, 2, 3 and 4 (Group 1: Long sintering cycle, Group 2: Intermediate sintering cycle, Group 3: Short sintering cycle, Group 4: Ultra-short sintering cycle) and sintered under the respective sintering cycles. The Ceramill® therm (Amann Girrbach) sintering furnace provided 3 sintering cycles ranging from the longest group-1 (19 hours), to the short sintering cycle group-3 (8 hours), with an intermediate sintering cycle group-2 (15 hours). The zircon (KDS) sintering furnace provided an ultra-short sintering cycle group-4 (2 hours). The testing of flexural strength was performed using a three-point bend test on a universal testing machine. Statistical analysis of the collected data was performed by one-way ANOVA using SPSS software.
RESULTS
One-way ANOVA showed no statistically significant difference in the flexural strength of full-contour monolithic zirconia sintered under the four different sintering cycles. (P > 0.05).
CONCLUSIONS
The flexural strength of full-contour monolithic zirconia was influenced to some extent by various sintering cycles. The longest sintering cycle (Group 1) showed the least flexural strength whereas the intermediate sintering cycle (Group 2) showed the highest flexural strength. Also, the ultra-short sintering cycle (Group 4) of 2 hours exhibited flexural strength comparable to the rest of the groups with longer sintering cycles, thus making the cycle a viable alternative to the conventional sintering cycles, thereby making the ‘tooth-in-a-day‘ possible for the patients.
Analytical evaluation and bioclinical validation of new aldosterone and renin immunoassays
Authors: Coulon Caroline , Lotierzo Manuela , Fesler Pierre , Roubille Camille , Badiou Stéphanie , Dupuy Anne Marie , Cristol Jean Paul 
Published: September 2022

Abstract

Objectives
Aldosterone and renin determinations play an important role in the etiological diagnosis of secondary hypertension. The analytical performances of new aldosterone and renin immunoassays on the Lumipulse G600II® system (Fujierbio) were investigated and compared with those of the iSYS® system (IDS) on patients concerned by medical investigations in a context of suspected or proven Primary aldosteronism.

Methods
By using the Lumipulse® G Aldosterone and Renin assays we performed imprecision study, linearity and method comparison (n=107). Accuracy of this new renin assay was tested using the International Standard (WHO IS 68/356). We also assessed the equivalence of the different samples types (n=29).

Results
The imprecision evaluation showed all CVs <3% and <6% for Lumipulse® G Aldosterone and Renin assays respectively. The linearity was excellent over the clinical range and the comparison with the iSYS® assays (n=79) showed a strong correlation (R2=1) despite a slight tendency to underestimation (bias of −17.53 pg/mL or 48.56 pmol/L for aldosterone and −15.395 pg/mL for renin). Moreover, the contingency studies based on diagnostic criteria showed that Lumipulse® G results lead to the same clinical diagnosis that iSYS® results. A clear correlation was obtained between EDTA and heparin plasma as well as with the serum for all range of measures.

Conclusions
The Lumipulse® G Aldosterone and Renin assays present performances compatible with a routine use in medical laboratories. The precise quantification in the low range can be of interest in some clinical contexts especially standing/laying tests. However, the standardisation against the WHO International Standard Renin would be advisable.
Ethnopharmacological study of medicinal plants in Kastamonu province (Türkiye)
Authors: Şen Gökhan , Akbulut Sefa , Karaköse Mustafa 
Published: September 2022

AbstractThis study is aimed at determining some of the plants traditionally used in the treatment of diseases by the local people living in Kastamonu province center and surrounding villages. A face-to-face questionnaire was applied and semi-structured interviews were conducted with 52 informants, 34 women and 18 men. Identification of 92 plants belonging to 41 families has been confirmed and their medicinal uses have been recorded. The most used families were Rosaceae (13 taxa), Asteraceae (11), and Lamiaceae (11). The most preferred folk recipes of medicinal plants was decoction (55 taxa) and in preparations and applications, the most used were the leaves (45 taxa). According to the International Classification of Primary Care categories, plants were the most used for digestive disorders (37 taxa), respiratory disorders (27 taxa), and urological disorders (24 taxa). The highest use-value was recorded forUrtica dioica(0.519), and highest relative frequency citation was recorded forTilia rubrasubsp.caucasica(0.231). Male genital diseases had the highest informant consensus factor value (0.83). New areas of use were also determined forPilosella leucopsilonsubsp. pilisquama,Galium palustre, andAstragalus nitens. With this study, new information for folkloric medicines is presented and the usage of herbal drugs in the study area are enhanced.
Preparation of PEEK-NH2/graphene network structured nanocomposites with high electrical conductivity
Authors: Liu Huizhi , Mei Qilin , Ding Guomin , Xiao Han , Chen Shuhui , Huang Zhixiong 
Published: September 2022

Abstract
The percolation thresholds of poly ether ether ketone/graphene (PEEK/Gr) composites in most studies are high due to the random distribution of Gr in the matrix. Here, aminated poly-ether-ether-ketone/graphene network (PEEK-NH2/GN) nanocomposites were prepared by electrostatic adsorption of PEEK-NH2 with positive charges and graphene oxide with negative charges, followed by in -situ reduction and hot-pressing. The GN structure of composites was well presented in the images of scanning electron microscope. The PEEK-NH2/GN nanocomposites exhibited excellent electrical conductivity with a maximum conductivity of 0.0634 S·cm−1 and a percolation threshold as low as 0.25 vol%. In addition, the maximum tensile strength of nanocomposites was reached at 93 MPa when the Gr content was 0.5 wt%. We believe that this approach is a new avenue for the production of low filler high conductive polymer composites with potential commercial prospects in various fields.
Periodic solution of a discrete commensal symbiosis model with Hassell-Varley type functional response
Authors: Chen Shangming , Chong Yanbo , Chen Fengde 
Published: September 2022

Abstract
A non-autonomous discrete commensal symbiosis model with Hassell-Varley type functional response is proposed and studied in this paper. Sufficient conditions are obtained for the existence of positive periodic solution of the system.
Bark from Nordic tree species – a sustainable source for amphiphilic polymers and surfactants
Authors: Kwan Isabella , Huang Tianxiao , Ek Monica , Seppänen Rauni , Skagerlind Peter 
Published: September 2022

AbstractMany of the amphiphilic molecules, or surfactants, are produced from fossil-based raw materials. With the increasing awareness of the climate situation, focus has shifted toward more environmentally friendly solutions to replace fossil-based products. This has led to more interest towards the forest. The circular bioeconomy is focused on making use of residues and waste and on optimizing the value of biomass over time via cascading. Nowadays, bark is seen as a waste product by industries and mainly incinerated as solid fuel. The bark contains interesting compounds but some of these are only available in low amounts, less than 1 % in the bark, while other components are present in several percentages. However, some of these components are potential candidates for the manufacture of amphiphiles and there seems to be a strong match between bark availability and surfactant demand. The global amount of bark available is approximately 359 million m3and more than 10 million m3of industrial bark are generated annually in Sweden and Finland. The bark of Norway spruce, Scots pine and silver birch contains approximately 25–32 % of extractives and part of these extractives has a potential as a surfactant backbone. This matches the global surfactant demand of about 15.6 million tons. Therefore, industrial bark has a significant potential value as a raw material source for amphiphilic molecules and polymers. This review focuses on betulin, condensed tannin and suberin. These compounds have been studied on individually and methods to extract them out from the bark are well investigated, but to utilize them as amphiphilic compounds has not been explored. With this review, we want to emphasis the potential of using bark, what today is seen as a waste product, as a raw material for production of amphiphiles. Moreover, a techno-economic analysis has been performed on betulin, tannins and suberin.
Effects of local fiber discontinuity on the fatigue strength parameter at the fiber inclusion corner in fiber-reinforced composites
Authors: Wang Cong-Man , Ping Xue-Cheng , Wang Xing-Xing 
Published: September 2022

Abstract
To comprehend the fatigue failure mechanism at the fiber discontinuity in fiber-reinforced composites, it is necessary to evaluate the local mechanical behaviors. The fatigue strength depends on the stress distribution at the fiber inclusion corner. An improved advanced finite element method (IAFEM) is proposed for the stress intensity factor (SIF) analysis at the fiber inclusion corner. In the IAFEM, the element stiffness matrix of singular inclusion corner element (SICE) is obtained, and the singular elastic field at the tip of the fiber inclusion is determined. The effects of load direction, fiber distribution, fiber geometry, and material properties on SIFs are analyzed numerically using the IAFEM. The difference in stress field distribution between two-dimensional and three-dimensional fiber inclusions is discussed. The IAFEIM and calculation results can provide reference for fatigue strength analysis and preparation of composite materials.
C-command constraints in German: A corpus-based investigation
Authors: Webelhuth Gert 
Published: September 2022

AbstractReinhart (1983) proposed that quantificational binding is subject to a surface c-command condition. Her claim has been widely accepted in the literature on the syntax-semantics interface. However, Barker (2012) presented systematic counterevidence against the c-command requirement from English. The current paper addresses the role of c-command constraints in the grammar of three phenomena in German: relative quantifier scope, quantificational binding, and negative polarity. The results of a large corpus study are presented that demonstrate empirically that scope of one quantifier over another, quantificational binding, and the licensing of negative polarity items in German are systematically possible in structural configurations where surface c-command cannot reasonably be assumed to obtain. Further corpus evidence is produced which shows that the non-c-commanding quantifiers in the examples typically occur in contexts where the set they quantify over is discourse-old or easy to accommodate. The overall picture that emerges from the empirical evidence is that topicality motivates wide scope, and scope rather than c-command licenses negative polarity items and bound pronouns.