bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intraoperative Analysis of Localization and Prevalence of Adhesions in the Abdominal Cavity
Authors: Клюйко Д.А. 
Published: February 2022

Введение. Профилактика и лечение спаечной болезни брюшной полости являются актуальной проблемной современной медицины, учитывая стремительный рост количества оперативных вмешательств и увеличение продолжительности жизни пациентов. Цель. Изучить топографо-анатомические особенности и распространенность спаечного процесса у пациентов со спаечной болезнью брюшной полости и спаечной кишечной непроходимостью. Материалы и методы. С помощью перитонеального индекса адгезии (PAI) во время хирургических вмешательств на органах брюшной полости оценены локализация и распространенность спаечного процесса у 194 пациентов. Результаты. Наиболее редкими причинами кишечной непроходимости стали конгломерат петель и выраженный спаечный процесс - по 6 случаев (11,8%), а также тотальный спаечный процесс (8 случаев (15,7%)), так как петли кишечника фиксированы и лишены подвижности. Напротив, наиболее часто кишечная непроходимость развивалась при слабо (22 случая (43,1%)) и умеренно (14 (27,5%)) выраженном спаечном процессе в брюшной полости. Выводы. Фиброзно-адгезивный процесс при спаечной болезни брюшной полости наиболее часто локализовался преимущественно в нижнем этаже брюшной полости и в области послеоперационного рубца после срединной лапаротомии, что связано с особенностями скопления патологического экссудата при воспалительных заболеваниях брюшной полости.
Introduction. Prevention and treatment of abdominal adhesions are an urgent problem of modern medicine, given the rapid increase in the number of surgical interventions and an increase in the life expectancy of patients. Purpose. To study the topographic and anatomical features and prevalence of the adhesive process in patients with adhesive abdominal disease and adhesive intestinal obstruction. Materials and methods. The localization and prevalence of the adhesive process in 194 patients were evaluated using the peritoneal adhesion index (PAI) during surgical interventions on abdominal organs. Results. The rarest causes of intestinal obstruction were a conglomerate of loops and a pronounced adhesive process - in 6 cases (11.8%), as well as a total adhesive process (8 cases (15.7%)), since the intestinal loops are fixed and motionless. On the contrary, intestinal obstruction most often developed in mild (22 cases (43.1%)) and moderate (14 (27.5%)) pronounced adhesive process in the abdominal cavity. Conclusions. The fibrous-adhesive process in abdominal adhesions was most often localized mainly in the lower floor of the abdominal cavity and in the area of the postoperative scar after median laparotomy, which is associated with the features of accumulation of pathological exudate in inflammatory diseases, insufficient sanitation and drainage of the abdominal cavity.
The Role of Cytochrome P450 Genes Polymorphic Variants in the Metabolism of Xenobiotics and the Pathogenesis of Hemoblastoses
Authors: Руденкова Т.В. , Костюк С.А. , Климкович Н.Н. , Демиденко А.Н. 
Published: February 2022

Генетический статус макроорганизма оказывает непосредственное влияние на процесс развития и вариант исхода как основного заболевания, так и его осложнений. Изучение роли генов-кандидатов в развитии, течении и вариантах исхода патологических процессов является перспективным направлением с точки зрения поиска объективных маркеров для персонификации профилактики, диагностики и лечения. Актуальным направлением является поиск и изучение факторов, способных оказывать влияние на фармакокинетику или фармакодинамику химиотерапевтических препаратов, что поможет прогнозировать развитие серьезных побочных эффектов у пациентов. Наиболее перспективными для изучения являются гены, контролирующие синтез ферментов, участвующих в процессах биотрансформации ксенобиотиков. Полиморфизм данных генов является одним из факторов, определяющих структуру и функции ферментов. Изучение молекулярно-генетических особенностей генов цитохрома P450 может заложить фундамент для разработки индивидуализированного подхода к профилактике и снижению частоты развития осложнений химиотерапии.
The genetic status of a macroorganism has a direct impact on the progress and the outcome of both the disease and complications. The study of genes-candidate role in the progress, course and outcomes of pathological processes is a promising direction for prevention, diagnosis and treatment personification objective markers finding. An actual direction is the search and study of factors that can influence the pharmacokinetics or pharmacodynamics of chemotherapeutic drugs, which will help predict the development of serious side effects in patients. The most promising for study are genes that control the synthesis of enzymes involved in the xenobiotics biotransformation processes. These genes polymorphism is one of the factors that determine structure and function of enzymes. The study of the cytochrome P450 genes characteristics can lay the foundation for the development of an individualized approach to prevention and reduction of the chemotherapy complications incidence.
Acute Leukemia in Children of the First Year of Life: Clinical Cases
Authors: Сачилович Д.С. , Пугачева Ж.Н. , Ярец Ю.И. , Ромашевская И.П. , Лукьяненко Е.П. , Демиденко А.Н. 
Published: February 2022

В работе представлены клинические случаи собственных наблюдений за пациентами первого года жизни с острыми лейкозами. Проанализированы гематологические и иммунофенотипические, молекулярно-генетические характеристики пациентов с острыми лимфобластными лейкозами в данной возрастной группе.
The paper presents clinical cases of our own observations of patients in the first year of life with acute leukemia. Hematological and immunophenotypic, molecular-genetic characteristics of patients with acute lymphoblastic and acute myeloid leukemias in this age group were analyzed.
Faktor-Faktor Yang Mempengaruhi Interaksi Sosial Pada Anak Usia Dini: Literatur Review
Authors: Batinah Batinah , Meiranny Arum , Arisanti Atika Zahria 
Published: February 2022

One form of early adolescence development is the ability to have interaction socially, social development can be affected if the kid's potential to take social roles makes children aware of the mind, feelings, and attitudes of others. the kid's high-quality or terrible self-image is encouraged if the kid is a success or not inside the affiliation. the kid's capacity to conform to the environment, acceptance of the surroundings and other high-quality reviews for the duration of social sports is a completely vital fundamental capital. Literature review aims to look at the related factors that have an effect on social interplay in early adolescence. In writing this newsletter, the method used was a overview of literature opinions contained in the database of health journals, particularly Google student and Pubmed, selected articles primarily based on complete textual content, unfastened open get admission to, in English and in Indonesian. Writing literature through the writer's database determined 16 articles thru Google student and four articles via PubMed. After the assessment was performed, there were 8 appropriate journals. The effects acquired were factors that have an effect on the capacity of interaction in kids, particularly: parenting, environment, gambling with friends and the usage of devices.

Keywords: Interaction influence factors, Social interaction ability, Early childhood.
Faktor Sosial Budaya yang Memengaruhi Kesehatan Ibu dan Anak (Studi Etnografi)
Authors: Salsabila Salsabila , Faizah Zakiyatul , Prasetyo Budi 
Published: February 2022

Maternal and child health as a key indicator of community welfare is measured by Maternal Mortality Rate (MMR) and Infant Mortality Rate (IMR). The problem of maternal and child mortality is a problem that cannot be separated from the culture or behavior of the community itself. The social and cultural system in the community is an important consideration in health services that can be utilized more optimally. The purpose of this study was to determine what cultural factors affect the health of mothers and children. This research is a rapid ethnographic assessment procedure (REAP) with a qualitative approach. Sampling technique using snowball or chain referral sampling. It is carried out sequentially from one participant to another. Is a variation of the purposive sample. The number of respondents as many as 8 people who fit the inclusion criteria. The data shown were the result of indepth interviews and FGDs (Focus Group Discussion). This study resulted in findings about: (1) Kyai become community role models in responding to life's problems ranging from political choices to choices of access to health. (2) Women do not have sufficient full power or empower themselves to choose health services, especially during pregnancy and childbirth. (3) The element of belief inherited from generation to generation also forms the knowledge system of the Cibitung community. (4) The livelihood system of farm laborers as the main source of the economy in Cibitung.
Keywords: Socio-Cultural, Ethnographic, Religious Systems, Kinship Systems, Knowledge Systems, Livelihood Systems
Tingkat Penerimaan Masyarakat terhadap Variasi Stik Berbahan Dasar Tepung Daun Katuk
Authors: Suciati Siti , Rustiana Ernik 
Published: February 2022

Leaf Katuk sticks are sticks made from wheat flour with the addition of katuk leaf flour. Moringa leaves contain polyphenols and steroids that can increase prolactin levels which play a role in producing breast milk. The purpose of this study was to determine the level of public acceptance of variations of sticks made from katuk leaf flour. This type of research is observational with a pre experimental design. The sample used in this study was 30 panelists who were determined by accidental sampling who met the inclusion criteria and the panelists were asked to feel and assess the variation of sticks made from katuk leaves. Assessment based on organoleptic theory. The variations of the Katuk Leaf Sticks were tested for differences in the level of acceptance. Statistical analysis of the acceptance rate using the Kruskal Wallis testing technique with an alpha value of 0.05. Based on the results of organoleptic and hedonic testing from the panelists, it is known that there are differences in the level of acceptance of variations of sticks made from katuk leaves both in terms of aroma, taste, texture and color with Asymp values. Sig < 0.005. The results of the different acceptance rates for variations of the katuk leaf sticks are that there are differences in the acceptance rates for formula 1, formula 2, and formula 3 sticks . The most accepted variation of sticks made from katuk leaves is in Formula 1.

Keywords: Acceptance Rate, Katuk Leaf Stick Variation, Organoleptic
The concept of active longevity as a tool for ensuring the economic security of territories in the context of population aging
Authors: Lavrikova Yu. G. , Vasil’eva E. V. 
Published: February 2022

Aim. The presented study aims to analyze the possibility of applying the concept of active longevity as a response to demographic threats to the economic security of territories.Tasks. The authors determine the theoretical and methodological prerequisites for the development of positive response measures regarding population aging based on the concept of active longevity to ensure the economic security of territories.Methods. This study uses the methods of analysis, grouping, and systematization. To substantiate the instrument of ensuring economic security in the context of population aging, the authors propose to make allowance for state interests in the economic sphere and the interests of elderly citizens.Results. Opportunities for applying the concept of active longevity to substantiate policies in the field of the economic security of territories are identified.Conclusion. The integration of the concept of active longevity into the political basis of ensuring the economic security of territories will make it possible to balance state interests in the economic sphere and the interests of elderly citizens in the context of population aging.
Russian tourism industry: consequences of the COVID-19 pandemic
Authors: Narbut V. V. 
Published: February 2022

Aim. The presented study aims to statistically assess the scale of the pandemic’s negative impact on the major indicators of the tourism industry in the Russian Federation.Tasks.The author shows the dynamics of the key indicators of the tourism industry before and during the pandemic; assesses the impact of the crisis on the activities of travel agencies; compares the amount of funds received from the sale of tourist products in Russian regions before and during the pandemic; assesses the statistical significance of changes in funds received from the sale of tourist products per company before and during the pandemic in the federal districts of Russiа.Methods. This study presents and analyzes data of the Federal State Statistics Service on the major activity indicators of organizations in the Russian travel industry from 2017 to 2020. The data mart of the Federal State Statistics Service serves as a source of information about the activities of travel agencies in the constituent entities of the Russian Federation. In the course of the study, the author uses the methods of grouping, variation, structural and dynamic data analysis. To obtain region-specific information, a corresponding analysis was performed in 2019–2020 in 85 constituent entities of the Russian Federation. A hypothesis about data distribution normality is tested using the Shapiro–Wilk test. A hypothesis about the significance of the differences in tourist activity indicators before and during the pandemic is tested using the non-parametric Wilcoxon test, since the nature of data distribution is different from normal.Results.It is found that the pandemic-related crisis has had a negative impact on all key indicators of the tourism industry. There have been significant job cuts, and the seasonality that is typical of the ‘healthy’ stage of the tourism industry’s development has been interrupted. The biggest decline in the number of employees is observed in the summer months of 2020. The impact of the crisis on average wages is manifested in a significant decline in April 2020 and fluctuations in the level of yearly average wages becoming more pronounced during the crisis. Quarantine measures contributed to the withdrawal of 227 companies from the Russian tourist services market, a 3.7-fold decrease in the number of tourist trips, and a 54.4% reduction in funds received from the sale of tourist products. The study presents the results of estimating the statistical significance of changes in the amount of funds received from the sale of tourist products per company before and during the pandemic in the federal districts of Russia.Conclusions.The impact of the pandemic is expressed in the breakdown of tourism development trends that preceded it, creating prerequisites for the restructuring of the industry and the emergence of new trends. A set of measures and joint actions of the state and tourism enterprises are needed to overcome the consequences of the pandemic in the tourism sector.
Transformation of the instruments of government regulation of the economy: from non-interference to strategic managementt
Authors: Volkova E. Yu. 
Published: February 2022

Aim. The presented study aims to investigate the evolution of interpretations of the government's role in the economy and to identify and describe the modern functions of the government in the economy and the corresponding regulatory instruments.Tasks. The authors theoretically analyze the approaches of major economic schools to the interpretation of the government's role in the economy in different periods; identify historical patterns in the transformation of government functions depending on external conditions; describe economic problems in the modern world; determine government functions and effective instruments for their implementation in the current context.Methods. This study uses general and special methods, such as induction and deduction, analysis and synthesis, generalization, systematization, comparative analysis, and content analysis. The methodological basis of the study includes the works of economists of various historical eras representing major economic schools, as well as modern research on the history of economic thought and government regulation.Results. The approaches of leading economic schools to substantiating the adequate degree of government intervention in the economy are analyzed – from the pre-scientific period to modern Nobel laureates. The historical and economic features of different eras are established, and the most effective instruments of government regulation of the economy are indicated for each era. Based on global development trends, the main economic features and problems of the XXI century are highlighted, which are universal in the context of globalization. The transformation of government functions in the modern economy is substantiated. The authors propose an original approach to the classification of government functions depending on their focus on solving specific problems and identify instruments for implementing new functions.Conclusions. The study highlights universal government functions in any society, such as producing public goods, protecting law and order, and updating legislation. The scope of government intervention in the economy and the selection of regulatory instruments are justified differently in the concepts of economic schools, depending on the characteristics of the external environment. During the development of human society, the degree of government influence on the economy changes. As social relations and technology become more advanced, government functions in the economy become more complex and new goals and forms of regulation appear. Government functions in the modern economy can be divided into four categories: ensuring economic development, facilitating technological progress, maintaining human capital, and economic globalization. The focus is shifting towards instruments for strategic planning, forecasting, and management and a program-oriented approach to the implementation of government functions.
Sistem Keamanan Smart Door Lock Menggunakan E-KTP (Elektroknik Kartu Tanda Penduduk) Berbasis Internet of Things (IoT)
Authors: Salim Djayus Nor , Pujisusilo Neira Anjar , Manik Samuel Pratama 
Published: February 2022

Pintu merupakan sebuah media yang digunakan sebagai jalan untuk masuk atau keluar dari ruangan. Untuk mempermudah suatu pekerjaan dibutuhkan suatu alat yang efektif dan efisien. Tujuan dari penelitian ini adalah membuat sebuah sistem keamanan smart door lock menggunakan e-KTP berbasis Internet Of Things (IoT) dengan metode waterfall. Sistem keamanan smart door lock dibangun menggunakan RFID (Radio Frequency Identification) berbasis IoT dengan menggunakan mikrokontroler NodeMCU ESP32 dan dapat terkoneksi pada internet sehingga bisa diakses melalui smartphone android. Sistem keamanan smart door lock ini menggunakan RFID (Radio Frequency Identification) sebagai pembukanya dan juga dengan memanfaatkan teknologi Internet Of Things (IoT) dengan menggunakan wireless yang terhubung pada aplikasi smartphone android. Berdasarkan hasil penelitian ini adalah RFID (Radio Frequency Identification) yang digunakan memiliki keamanan yang lebih terjamin, karena yang mana untuk mendaftarkan e-KTP dengan menggunakan aplikasi Blynk pada smartphone android, jadi tidak semua orang bisa mendaftarkan e-KTP, dan juga terdapat buzzer akan mengeluarkan suara bip 1x apabila pintu dapat dibuka sesuai dengan frekuensi 13,56MHz yang terdapat dalam RFID yang dapat membaca e-KTP dengan jarak 50 mm. Buzzer akan mengeluarkan suara bip 2x apabila e-KTP tidak terdaftar pada alat tersebut. Solenoid Door Lock dapat membuka tuas pintu apabila e-KTP tidak sesuai dengan NodeMCU ESP32, solenoid akan mengunci kembali dalam waktu 2 detik. Kesimpulan dari penelitian yang dilakukan telah dirancang dan dibangun sistem keamanan smart door lock menggunakan e-KTP berbasis Internet Of Things (IoT).
Evaluasi Efektifitas Laporan Pemakaian dan Lembar Permintaan Obat (LP-LPO) Puskesmas Kota Jambi
Authors: Salmah Hisran Hamad 
Published: February 2022

The importance of valid data means the achievement of lp-LPO objectives as a report on the use and demand of drugs to the installation. The purpose of this study is tosee how effective the monthly report of drugs (LP-LPO) in health centers by measuringindicators of demand accuracy, demand suitability and delivery, accuracy of administration to sub units and measuring the level of drug availability. Effective here means a good report means the availability of an effective drug reporting system in the health center and its network. Method: Research design is descriptively quantitative with an observative and evaluative approach. Data on drug demand and distribution were collected from LPLPO Quarters I, 2,3 and 4. The amount of drugs observed was 20 items of the drug. Observations are made on the suitability of filling data in the demand column and the distribution of LPLPO between calculations should be in theory with those stated in lp-LPO. Results: LP-LPO has been able to describe the availability of puskesmas drugs. The average availability of puskesmas drugs is 2.11 months which belongs to the safe category. The suitability of requests and calculations, submitted by puskesmas through LP-LPO is good enough, according to 61.5% is in accordance with the calculation according to standards. The suitability of puskesmas request submitted through LP-LPO, 80.3% is in accordance with the grant given by the Pharmaceutical installation
Pengalaman Kepala Ruangan dalam Mengelola Ruangan yang Merawat Pasien Covid 19
Authors: Relly Brension , Afiyanti Yati , Syafwani Muhammad 
Published: February 2022

The recent Covid 19 outbreak has grown from a public health emergency to a major global pandemic. As the Covid 19 pandemic emerged as a global health care crisis, scientists around the world were actively developing prophylactic and therapeutic interventions. During the pandemic, the management of the chief strategist played a very important role. The strategy taken must be able to adapt very quickly, whether organizational, corporate, business unit, or operational level. The management of Man, Money, Materials, Machines, and Methods in the element of management becomes crucial to be managed by a head of the room This research aims to explore in depth the Experience of the Head of Room in managing the Room That Cares for Covid 19 Patients. Research methods with qualitative data were obtained through indepth interviews on 10 participants of Hospital A and B in Palangka Raya central Kalimantan using qualitative methods with purposive sampling techniques. The results of the study found 6 main themes, namely (1). Management of Resources of Manausia Nurse, (2). Financial Management, (3). availability of consumables, (4). Readiness of medical devices, (5) Room management methods, (6). evaluation of management of human resources management, finance, facilities, availability of tools, room governance methods. The results of this study concluded that the management and evaluation of the head of the room during the Covid 19 pandemic needs the management of human resources, finance, availability of consumables, tools and methods of room governance to be of particular concern to hospital managers who provide health services to Covid 19 patients.