bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relativistic solar particle event on 28 October 2021: Evidence of particle acceleration within and escape from the solar corona
Authors: Klein Karl-Ludwig , Musset Sophie , Vilmer Nicole , Briand Carine , Krucker Säm , Francesco Battaglia Andrea , Dresing Nina , Palmroos Christian , Gary Dale E. 
Published: June 2022

Aims.We analyse particle, radio, and X-ray observations during the first relativistic proton event of solar cycle 25 detected on Earth. The aim is to gain insight into the relationship between relativistic solar particles detected in space and the processes of acceleration and propagation in solar eruptive events.Methods.To this end, we used ground-based neutron monitor measurements of relativistic nucleons and space-borne measurements of electrons with similar speed to determine the arrival times of the first particles at 1 AU and to infer their solar release times. We compared the release times with the time histories of non-thermal electrons in the solar atmosphere and their escape to interplanetary space, as traced by radio spectra and X-ray light curves and images.Results.Non-thermal electrons in the corona are found to be accelerated in different regions. Some are confined in closed magnetic structures expanding during the course of the event. Three episodes of electron escape to the interplanetary space are revealed by groups of decametric-to-kilometric type III bursts. The first group appears on the low-frequency side of a type II burst produced by a coronal shock wave. The two latter groups are accompanied at higher frequencies by bursts with rapid drifts to both lower and higher frequencies (forward- or reverse-drifting bursts). They are produced by electron beams that propagate both sunward and anti-sunward. The first relativistic electrons and nucleons observed near Earth are released with the third group of type III bursts, more than ten minutes after the first signatures of non-thermal electrons and of the formation of the shock wave in the corona. Although the eruptive active region is near the central meridian, several tens of degrees east of the footpoint of the nominal Parker spiral to the Earth, the kilometric spectrum of the type III bursts and the in situ detection of Langmuir waves demonstrate a direct magnetic connection between the L1 Lagrange point and the field lines onto which the electron beams are released at the Sun.Conclusions.We interpret the forward- and reverse-drifting radio bursts as evidence of reconnection between the closed expanding magnetic structures of an erupting flux rope and ambient open magnetic field lines. We discuss the origin of relativistic particles near the Earth across two scenarios: (1) acceleration at the CME-driven shock as it intercepts interplanetary magnetic field lines rooted in the western solar hemisphere and (2) an alternative where the relativistic particles are initially confined in the erupting magnetic fields and get access to the open field lines to the Earth through these reconnection events.
Our Treatment Strategy for CMC-1 Osteoarthritis
Authors: Myncke Irisa , Vanhees Mathias , Verstreken Frederik 
Published: June 2022

AbstractOsteoarthritis of the carpometacarpal joint of the thumb ( CMC-1) is a common problem and many patients will seek medical attention and may eventually need surgical treatment. As no treatment option has shown consistent superiority, a variety of surgical procedures have been proposed. In this review paper we present our algorithm for the approach of symptomatic CMC-1 osteoarthritis, supported by scientific evidence and our personal experience. It is primarily based on patient demands, status of CMC-1 disease and associated problems around the thumb. The selection of a successful surgical treatment plan with restoration of a pain free and fully functional thumb is the goal. We’ll outline the pro’s and con’s of the surgical procedures and although trapeziectomy has long been the gold standard, the advent of reliable total joint arthroplasties with good short and long-term outcome reports has changed our treatment protocol completely.
Retrospective Review of Surgical Site Infections after Endoscopic Endonasal Sellar and Parasellar Surgery: Multicenter Quality Data from the North American Skull Base Society
Authors: Saleh Sara , Sullivan Stephen E. , Bellile Emily , Roxbury Christopher , Das Paramita , Hachem Ralph Abi , Ackall Feras , Jang David , Celtikci Emrah , Sahin Muammer Melih , D'souza Glen , Evans James J. , Nyquist Gurston , Khalafallah Adham , Mukherjee Debraj , Rowan Nicholas R. , Camp Samantha , Choby Garret , Gompel Jamie J. Van , Ghiam Michael K. , Levine Corinna G. , Field Melvin , Adappa Nithin , Locke Tran B. , Rassekh Christopher , Sweis Auddie M. , Goyal Neerav , Zacharia Brad , Wilson Meghan N. , Patel Shivam , Gardner Paul A. , Snyderman Carl H. , Wang Eric W. , Glancz Laurence Johann , Bagchi Ananyo , Dow Graham , Robertson Iain , Rangarajan Sanjeet V. , Michael L. Madison , McKean Erin L. 
Published: June 2022

Abstract
Introduction Transnasal access to the anterior skull base provides a minimally invasive approach for sellar and parasellar masses compared with its open counterparts. The unique microbiome of the sinonasal mucosa provides distinct challenges not encountered with other cranial approaches. The use of antibiotics in these cases has not been standardized, and data remain scarce regarding infectious outcomes.
Methods We conducted a multicenter retrospective analysis of shared quality data points for the endoscopic endonasal approach (EEA) for pituitary adenomas, along with other sellar and parasellar region masses that were included by participating institutions. Patient and operative characteristics, perioperative and postoperative antibiotic regimens and their durations, intraoperative and postoperative cerebrospinal fluid leak, and onset of postoperative meningitis and sinusitis were compared.
Results Fifteen institutions participated and provided 6 consecutive months' worth of case data. Five hundred ninety-three cases were included in the study, of which 564 were pituitary adenomectomies. The incidences of postoperative meningitis and sinusitis were low (0.67 and 2.87% for all pathologies, respectively; 0.35% meningitis for pituitary adenomas) and did not correlate with any specific antibiotic regimen. Immunocompromised status posed an increased odds of meningitis in pituitary adenomectomies (28.6, 95% confidence interval [1.72–474.4]).
Conclusions The results show no clear benefit to postoperative antimicrobial use in EEA, with further larger studies needed.
The Toronto Upper Gastrointestinal Cleaning Score: a prospective validation study
Authors: Khan Rishad , Gimpaya Nikko , Vargas Jose I. , Ramkissoon Anushka , Seleq Samir , Gholami Reza , Akhtar Hisham J. , Bansal Rishi , Scaffidi Michael A. , Amin Sunil , Bollipo Steven , Kral Jan , Lui Rashid , Pawlak Katarzyna M. , Sandhu Dalbir S. , Bilal Mohammad , de-Madaria Enrique , Siau Keith , Charabaty Aline , Hashim Almoutaz , Sánchez-Luna Sergio A. , Teshima Christopher W. , May Gary R. , Mosko Jeffrey D. , Walsh Catharine M. , Grover Samir C. 
Published: June 2022

Background Assessment of mucosal visualization during esophagogastroduodenoscopy (EGD) can be improved with a standardized scoring system. To address this need, we created the Toronto Upper Gastrointestinal Cleaning Score (TUGCS).
Methods We developed the TUGCS using Delphi methodology, whereby an international group of endoscopy experts iteratively rated their agreement with proposed TUGCS items and anchors on a 5-point Likert scale. After each Delphi round, we analyzed responses and refined the TUGCS using an 80 % agreement threshold for consensus. We used the intraclass correlation coefficient (ICC) to assess inter-rater and test–retest reliability. We assessed internal consistency with Cronbach’s alpha and item-total and inter-item correlations with Pearson’s correlation coefficient. We compared TUGCS ratings with an independent endoscopist’s global rating of mucosal visualization using Spearman’s ρ.
Results We achieved consensus with 14 invited participants after three Delphi rounds. Inter-rater reliability was high at 0.79 (95 %CI 0.64–0.88). Test–retest reliability was excellent at 0.83 (95 %CI 0.77–0.87). Cronbach’s α was 0.81, item-total correlation range was 0.52–0.70, and inter-item correlation range was 0.38–0.74. There was a positive correlation between TUGCS ratings and a global rating of visualization (r = 0.41, P = 0.002). TUGCS ratings for EGDs with global ratings of excellent were significantly higher than those for EGDs with global ratings of fair (P = 0.01).
Conclusion The TUGCS had strong evidence of validity in the clinical setting. The international group of assessors, broad variety of EGD indications, and minimal assessor training improves the potential for dissemination.
Evaluation of the Content of Ophthalmology Fellowship Program Web sites
Authors: Alsaloum Peter , Alsaloum Matthew , Kim Tyler J. , Zheng David X. , Valentim Carolina C. S. , Muste Justin C. , Goshe Jeffrey M. , Singh Rishi P. 
Published: June 2022

Abstract
Purpose To assess the availability and content of fellowship program Web sites (FPWs) among ophthalmology subspecialties.
Design This is a cross-sectional study.
Subjects Web sites of all Association of University Professors of Ophthalmology-accredited fellowship programs in five subspecialties (i.e., surgical retina and vitreous; cornea, external disease, and refractive surgery; glaucoma; neuro-ophthalmology; and pediatric ophthalmology).
Methods FPWs were assessed for the presence of 26 key content criteria encompassing program demographics (n = 13), features (n = 10), and social life (n = 3). The presence of each content criterion as well as the content criteria groups were compared across subspecialties.
Main Outcome Measures The main outcome measured is the average percentage of key content criteria present among ophthalmology fellowship Web sites.
Results Among 266 accredited fellowship programs, 240 (90.2%) had Web sites. On average, Web sites reported 14.9 of 26 key content criteria (57.2%), 8.29 of 13 demographic criteria (63.8%), 5.84 of the 10 program features criteria (58.4%), and 0.705 of the 3 social life criteria (23.5%). Significant differences were identified among subspecialties in the presence of program description (p = 0.046), hospital affiliation (p < 0.001), names of current fellows (p = 0.004), case diversity (p = 0.001), and surgical statistics (p = 0.015). The average number of key criteria differed between subspecialties (p < 0.001).
Conclusion There is significant heterogeneity in program fellowship Web site content among ophthalmology subspecialties. Information regarding social life, such as wellness programs and community information, was largely absent across all disciplines. Addressing missing information on ophthalmology FPWs may help optimize program-applicant fit.
How to Perform Discriminant Analysis in Medical Research? Explained with Illustrations
Authors: Dhamnetiya Deepak , Goel Manish Kumar , Jha Ravi Prakash , Shalini Shalini , Bhattacharyya Krittika 
Published: June 2022

AbstractDiscriminant function analysis is the statistical analysis used to analyze data when the dependent variable or outcome is categorical and independent variable or predictor variable is parametric. It is a parametric technique to determine which weightings of quantitative variables or predictors best discriminates between two or more than two categories of dependent variables and does so better than chance. Discriminant analysis is used to find out the accuracy of a given classification system in predicting the sample into a particular group. Discriminant analysis includes the development of discriminant functions for each sample and deriving a cutoff score that is used for classifying the samples into different groups. Discriminant function analysis is a statistical analysis used to find out the accuracy of a given classification system or predictor variables. This article explains the basic assumptions, uses, and necessary requirements of discriminant analysis with a real-life clinical example. Whenever a new classification system is introduced, discriminant function analysis can be used to find out the accuracy with which the classification is able to differentiate a particular sample into different groups. Thus, it is a very useful tool in medical research where classification is required.
Maternal Deaths from COVID-19 in Brazil: Increase during the Second Wave of the Pandemic
Authors: Scheler Carlos André , Discacciati Michelle Garcia , Vale Diama Bhadra , Lajos Giuliane Jesus , Surita Fernanda Garanhani , Teixeira Julio Cesar 
Published: June 2022

Abstract
Objective To compare death rates by COVID-19 between pregnant or postpartum and nonpregnant women during the first and second waves of the Brazilian pandemic.
Methods In the present population-based evaluation data from the Sistema de Informação da Vigilância Epidemiológica da Gripe (SIVEP-Gripe, in the Portuguese acronym), we included women with c (ARDS) by COVID-19: 47,768 in 2020 (4,853 obstetric versus 42,915 nonobstetric) and 66,689 in 2021 (5,208 obstetric versus 61,481 nonobstetric) and estimated the frequency of in-hospital death.
Results We identified 377 maternal deaths in 2020 (first wave) and 804 in 2021 (second wave). The death rate increased 2.0-fold for the obstetric (7.7 to 15.4%) and 1.6-fold for the nonobstetric groups (13.9 to 22.9%) from 2020 to 2021 (odds ratio [OR]: 0.52; 95% confidence interval [CI]: 0.47–0.58 in 2020 and OR: 0.61; 95%CI: 0.56–0.66 in 2021; p < 0.05). In women with comorbidities, the death rate increased 1.7-fold (13.3 to 23.3%) and 1.4-fold (22.8 to 31.4%) in the obstetric and nonobstetric groups, respectively (OR: 0.52; 95%CI: 0.44–0.61 in 2020 to OR: 0.66; 95%CI: 0.59–0.73 in 2021; p < 0.05). In women without comorbidities, the mortality rate was higher for nonobstetric (2.4 times; 6.6 to 15.7%) than for obstetric women (1.8 times; 5.5 to 10.1%; OR: 0.81; 95%CI: 0.69–0.95 in 2020 and OR: 0.60; 95%CI: 0.58–0.68 in 2021; p < 0.05).
Conclusion There was an increase in maternal deaths from COVID-19 in 2021 compared with 2020, especially in patients with comorbidities. Death rates were even higher in nonpregnant women, with or without comorbidities.
Critical Care Nutrition Support following Cardiac Surgery in the Pediatric and Adult Population—A Review Article
Authors: Hote Milind Padmakar , Kapoor Poonam Malhotra , Malakar Jaydeep 
Published: June 2022

AbstractCardiac surgical patients in the intensive care unit certainly develop complex nutritional issues. Nutrition support is indicated in these subsets of patients and the same may be customized depending on individual patient characteristics. This review article that aims to examine the American Society for Parenteral and Enteral Nutrition guidelines for the use of parenteral and enteral nutrition in pediatric and adult cardiac surgical patients in cardiac critical care/intensive care unit evaluates the evidence related to the use of nutritional screening and nutritional assessment. The goal of this review is to enrich the discussion contained in the clinical guidelines and simplify the guideline statements to provide a platform for cardiac care providers to implement into their daily practice related to nutrition support in postoperative cardiac surgery patients.
Investigation of the structural, morphological, and magnetic properties of small crystalline Co–Cu ferrite nanoparticles in the single-domain regime
Authors: Alzoubi Gassem M. , Masadeh Ahmad S. , Shatnawi Moneeb T. M. 
Published: June 2022

Single-domain Co0.5Cu0.5Fe2O4 ferrite nanoparticles with a crystallite size of 23 nm were hydrothermally prepared and characterized using x-ray diffraction, transmission electron microscopy, Fourier-transform infrared (FT-IR) spectroscopy, and vibrating sample magnetometry. According to the Rietveld refinement results, the prepared nanoparticles were single-phase with spinel type structures. The transmission electron microscope measurements demonstrated that the nanoparticles were spherical in shape. The FT-IR spectrum showed two principle absorption bands, confirming the characteristic features of cubic spinel ferrites. Magnetization data revealed that the prepared nanoparticles were ferrimagnetic from room temperature to 10 K, with well-defined saturation magnetization, coercivity, and remanence magnetization. The remanence magnetization and coercivity were found to increase with decreasing temperature. The value of room temperature squareness ratio (Mr/Ms) of 0.42 was found to be somewhat similar to that expected (0.5) for a system of noninteracting single-domain nanoparticles, suggesting that the prepared nanoparticles are in a single-domain regime. The temperature dependence of coercivity was found to have slight deviations from Kneller’s law, possibly due to interactions between nanoparticles. The zero field cooled–field cooled curves indicated that below 150 K, the nanoparticles were ferrimagnetic dressed with spin-glass behavior, resulting from interactions between the ferrimagnetic nanoparticles and/or random freezing of surface spins.
Investigation of a nanostructured GaP/MoS2 p-n heterojunction photodiode
Authors: Novák J. , Laurenčíková A. , Eliáš P. , Hasenöhrl S. , Sojková M. , Kováč J. , Kováč J. 
Published: June 2022

We report on the properties of a GaP/MoS2 heterojunction prepared on a nanocone (NC)-structured GaP substrate and a planar GaP substrate. The nanocone-structured GaP substrate was prepared by the growth of GaP NCs at gold seeds on a ⟨111⟩B GaP substrate at 650 °C by metal organic vapor phase epitaxy. At this growth temperature, most NCs exhibited a hexagonal symmetry with six heavily facetted sides that contained numerous facets, ledges, and edges with a large surface area. A thin Mo layer was deposited on both types of GaP substrates by direct current magnetron sputtering. The Mo layer was then sulfurated at 700 °C and turned into a MoS2 layer. Electrical and optical characterization gave evidence that a PN heterojunction formed between GaP and MoS2 during the sulfuration process. The spectral response measurement showed two separate regions between 400 and 550 nm linked with the generation of carriers in GaP and between 550 and 1100 nm associated with the generation of carriers in the MoS2 layer. The planar GaP/MoS2 heterojunction generated a lower photocurrent compared with the GaP/MoS2 heterojunction that formed on the nanocone-structured GaP substrate. The results support theoretical assumptions that edge rich substrates can help to increase the quality of deposited 2D materials.
Transport properties of n-ethylene glycol aqueous solutions with focus on triethylene glycol–water
Authors: Santos C. I. A. V. , Barros M. C. F. , Ribeiro A. C. F. , Bou-Ali M. M. , Mialdun A. , Shevtsova V. 
Published: June 2022

Soret effect and diffusion in triethylene glycol (TEG)–water mixtures were investigated as a function of concentration at 25 °C by means of optical digital interferometry, with the use of a classical Soret cell. Diffusion D, thermal diffusion DT, and Soret ST coefficients are described for the full concentration range and an analysis is made individually for TEG–water mixture and within a series of n-ethylene glycol (n-EG) aqueous systems. All coefficients decrease with increasing the concentration of TEG and n-EG. ST shows a change of sign with concentration, and this change is directly related to the ability of the n-EG molecule to establish hydrogen bonding with water. Diffusion and thermal diffusion coefficients present a plateau behavior with increasing concentration, showing the occurrence of changes in the preferential interactions in aqueous solution with concentration and meaning that, at high TEG composition, ether oxygens can be involved in the molecular interactions.
Continuous-wave and pulsed operation of Ho:YLF laser end-pumped by Tm:fiber laser
Authors: Babaiy Tooski Majid , Maleki Abbas , Eslami Majd Abdolah , Ebadian Hassan 
Published: June 2022

Abstract
Continuous-wave and pulsed operation of a Ho:YLF laser was demonstrated. A Tm:fiber laser with 70 W output power was used for the pump source. In this experimental setup, the end-pumped gain medium with 0.5% and 1% Ho concentration in the optical resonators were used. In the continuous-wave regime, 14.2 and 12.8 W linearly polarized power with a concave-concave resonator for 1.0% and 0.5% Ho dopes were extracted, respectively. These amounts correspond to slope efficiencies of 51.9% and 71.3% and optical-to-optical efficiencies of 39.4% and 54.7% for absorbed pump power, respectively. To avoid optical damage, a U-shaped concave-concave resonator was installed, and the resulting spot size in the resonator was about 1.31 mm. The spot size changes about 10% along the total physical length of the resonator. In the pulsed operation regime, for 0.5% Ho concentration with 20 ms pump pulse duration and 10 Hz repetition rates, the free-running output energy was 172 mJ with 16 ms pulse duration. In addition, the absorbed pump energy was about 485 mJ, corresponding to the slope and the optical-to-optical efficiencies of 14.8% and 12.3%, respectively. Also, 27 mJ pulse energy with 29.7 ns duration was achieved for Q-switched operation. Finally, the angle of output beam divergence was measured at approximately 1.1 mrad, and the laser emission wavelength was 2.0568 µm with 0.0065 µm line width.
A New Statistical Distance Scale for Planetary Nebulae, Based on Gaia EDR3
Authors: Ali A. , Algarni E. , Mindil A. , Alghamdi S. A 
Published: June 2022

Abstract
The present work aims to build a new statistical distance scale for planetary nebulae (PNe) based on a rigorous calibration sample. The distances of the calibration sample are derived from the trigonometric parallax method using the recent measurements of Gaia Early Data Release 3 (Gaia EDR3). The new distance scale is created by applying the well-known linear relationship between the radio surface brightness temperature and the nebular radius. The calibration sample is made up of 96 PNe of accurately computed distances with uncertainties less than 20%. Earlier ground- and space-based trigonometric parallaxes of PNe display inconsistency with those of Gaia, particularly the Hipparcos results. In addition, these measurements have appreciably lower precision than those of Gaia. When compared to the trigonometric technique, the expansion and kinematic methods exhibited more consistency than the spectroscopic, extinction, gravity, and photoionization methods. Furthermore, contrary to earlier results in the literature, the extinction and gravity methods, on average, underestimate and slightly overestimate the PN distances respectively. As a byproduct of extracting the Gaia parallaxes, we detect the radial velocity and variability for 14 and 3 PN central stars (CSs), respectively. To our knowledge, the variability of Hen 2-447 CS has been determined for the first time.