bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impaired Verbal Memory Recall in Patients With Axonal Degeneration and Serum Glycine-Receptor Autoantibodies—Case Series
Authors: Hansen Niels , Bartels Claudia , Stöcker Winfried , Wiltfang Jens , Fitzner Dirk 
Published: January 2022

BackgroundGlycine receptor antibody-associated neuropsychiatric disease is currently known to be dominated by the phenotypes stiff-person syndrome and progressive encephalomyelitis entailing rigidity and myoclonus. In our case series we aim to depict the less-often reported feature of cognitive impairment associated with glycine receptor antibodies.MethodsWe investigated five patients with cognitive impairment varying from mild cognitive impairment to dementia associated with serum glycine receptor antibodies. Mild and major neurocognitive disorders were diagnosed according to the DSM-5 (fifth edition of the Diagnostic and Statistical Manual of Mental Disorders). Neuropsychology via Consortium to Establish a Registry for Alzheimer's Disease (CERAD) testing results, psychopathology data via the Manual for the Assessment and Documentation of Psychopathology in Psychiatry (AMDP), cerebrospinal fluid analysis and magnetic resonance imaging data were retrospectively analyzed from patient files.ResultsWe identified five patients with cognitive impairment as the main neuropsychiatric feature associated with serum glycine receptor antibodies. One patient also presented akinetic rigidity syndrome. The psychopathology comprised disorders of attention and memory, orientation, formal thought, and affect. In addition to suffering deficits in verbal memory function, figural recall, phonematic fluency, and globally deteriorated cognitive function, these patients presented seriously impaired memory recall in particular. Tau protein and phosphorylated tau protein 181 were elevated in 75% of patients.ConclusionsOur results suggest that axonal neurodegeneration and especially impaired verbal memory recall in addition to deficits in verbal and figural memory characterize patients with progressive cognitive impairment associated with glycine receptor antibodies. This unresolved issue should be clarified by researchers to discover whether axonal degeneration is merely an age-related phenomenon or one related to glycine-receptor autoantibodies in old age. Cognitive impairment as a neuropsychiatric syndrome of glycine-receptor antibody disease is a potential, conceivable, but so far unproven additional feature requiring deeper large-scale investigations and consideration during differential diagnosis in memory clinics.
Mediating Effect of Body Mass Index and Dyslipidemia on the Relation of Uric Acid and Type 2 Diabetes: Results From China Health and Retirement Longitudinal Study
Authors: Cheng Fang , Li Yanzhi , Zheng Han , Tian Lu , Jia Hongying 
Published: January 2022

ObjectiveThis study assessed temporal relationships of serum uric acid (SUA) with blood glucose and determine the mediating effects of body mass index (BMI) and dyslipidemia on the relation of SUA and risk of type 2 diabetes.MethodsParticipants aged ≥ 45 years were participated in 2011 and followed up until 2015. Cox proportional hazards regression with a robust variance estimator was performed to explore the association of SUA with the risk of diabetes, and crosslagged path analysis was introduced to examine the temporal relationships between SUA and blood glucose. A mediation analysis was finally used to identify the mediating effect of BMI and dyslipidemia on the relation of SUA and the future risk of diabetes.ResultsA total of 9,020 participants were included with an average age of 58.59 years at baseline in 2011, and 53.6% of them were women. Linear dose–response relationship was identified by restricted spline cubic analysis between baseline SUA and follow-up blood glucose (the non-linear trend for fasting plasma glucose (FPG): β2 = −0.71, p = 0.52; for HbA1c: β2 = 0.05, p = 0.07; for risk of diabetes: β2 = 0.12, p = 0.39). Additionally, compared with the lowest quartiles of SUA, the adjusted risk ratios of diabetes were 1.00 (95% CI: 0.82–1.23), 1.08 (95% CI: 0.89–1.31), and 1.37 (95% CI: 1.11–1.96) for quartile 2–4 (p-trend &lt; 0.01), respectively. Further additional adjustments for BMI or dyslipidemia, these ratios were not statistically significant. In addition, a unidirectional relationship from baseline SUA to follow-up FPG (ρ1 = 0.24, p = 0.03) was further confirmed using crosslagged path analysis. After stratifying by genders, the above results were only significant in the women subgroup, and we thus conducted a mediation analysis in women and found that the BMI and dyslipidemia partially mediated the effect of SUA on diabetes with a 23.05 and 18.82% mediating effect, respectively.ConclusionsThese findings provide strong evidence that hyperuricemia preceded diabetes, and the effect of baseline SUA on follow-up type 2 diabetes was more pronounced among middle-aged and elderly Chinese women, especially in postmenopausal women, and this effect is partly mediated by BMI and dyslipidemia at baseline.
The Determinants of Length of Homeless Shelter Stays: Evidence-Based Regression Analyses
Authors: Hao Haijing , Garfield Monica , Purao Sandeep 
Published: January 2022

Objective: To identify determinants that contribute to the length of homeless shelter stay.Methods: We utilized a unique dataset from the Homeless Management Information Systems from Boston, Massachusetts, United States, which contains 44,197 shelter stays for 17,070 adults between Jan. 2014 and May 2018.Results: Our statistical analyses and regression model analyses show that factors that contribute to the length of a homeless shelter stay include being female, senior, disability, being Hispanic, or being Asian or Black African. A significant fraction of homeless shelter stays (76%) are experienced by individuals with at least one of three disabilities: physical disability, mental health issues, or substance use disorder. Recidivism also contributes to longer homeless shelter stays.Conclusion: The results suggest possible program and policy implications. Several factors that contribute to longer homeless shelter stay, such as gender, age, disability, race, and ethnicity, may have funding implications. Age may point to the need for early interventions. Disability is developmental and may benefit from treatment and intervention. Finally, we find that length of stay and recidivism are not independent, and may form a vicious cycle that requires additional investigation.
Prevalencia de dolor crónico en personas adultas en Costa Rica, enero-2020 a marzo-2021
Authors: Acuña-Aguilar Carlos , Fernández-Cordero Ariel , Benavides-Lara Adriana 
Published: January 2022

Introducción: el objetivo del estudio fue determinar el comportamiento epidemiológico y la atención de las personas adultas que cursan con dolor crónico en Costa Rica. Metodología: estudio observacional transversal mediante una encuesta telefónica realizada a personas mayores de 19 años, residentes en Costa Rica por al menos tres meses. Se estimó una muestra aleatoria con representatividad nacional, ponderada según los 82 cantones del país. Se determinó la prevalencia de dolor crónico con su respectivo IC95% para el país y cada provincia. Resultados: se realizaron entrevistas a 375 personas, con una media de edad de 57,4 años (DE 17,4); 73,1% mujeres. Ciento ocho personas reportaron dolor crónico para una prevalencia nacional de 28,8% (IC95% 24,3-33,7), con una media de edad significativamente mayor que la población entrevistada (62,9 años; DE 14,2). No se encontraron diferencias por provincia. La media de duración del dolor fue 61 meses (DE: 104,7; rango 36-756 meses). La artrosis como causa única se presentó en el 65,6% de los casos. El miembro inferior fue la localización más frecuente (53,7%). Para la intensidad del dolor (escala numérica del 0 a 10): 69,4% puntuó igual o superior a 5, y 29,6% entre 8-10. Según su frecuencia, 54% presentaron dolor a diario; la mayoría lo describieron como entumecimiento (40,7%). Aproximadamente 83,3% utilizaron medidas farmacológicas, principalmente antiinflamatorios no esteroideos (76,9%); 64% de estos medicamentos fueron prescritos por un médico, 30% se auto medicaron o siguieron consejos (publicidad o amigos). La esfera de vida diaria más afectada fue la laboral (70,4%), seguida de alteraciones en el sueño (59,3%). Conclusión: el dolor crónico en las personas adultas de Costa Rica es un problema de salud pública, con una prevalencia similar a la reportada en Latinoamérica, que aumenta significativamente con la edad. La mayoría de las personas que lo padecen se ven afectadas diariamente por periodos prolongados. Se destaca la baja utilización de opioides, un elevado consumo de AINES y automedicación.
El rol de la investigación en la profesión de la Enfermería
Authors: Ricardo-Rosendo Amaya Córdova , Jaime-Villafuerte Mayra Yariza , Chong-Manzano Susan Stephany , Suarez-Bastidas Beibelin Emily 
Published: January 2022

Objetivo: Evaluar el rol de la investigación en la profesión de la enfermería. Metodología: De corte documental – descriptiva, fundamentada en la bibliografía revisada desde el punto de vista profesional y social de la importancia de utilizar la investigación para hacer compatible la práctica de los cuidados con la evidencia científica a través de las bases de datos de Cuidatge, Cuiden, Medline, Scielo, PubMed y Cinahl. Conclusión: Se explica el rol de la investigación en la praxis de la enfermería como aquella que permite lograr fomentar la autonomía e independencia profesional y hacerla innegable en los equipos científicos interdisciplinarios para ser percibida por usuarios y la sociedad en general.
Gestión del flujo de efectivo en organizaciones del sector no financiero popular y solidario
Authors: Iza-López Karina Johanna , Erazo-Álvarez Juan Carlos 
Published: January 2022

La gestión del flujo de efectivo es un pilar básico para las pequeñas y medianas empresas que integran el sector no financiero popular y solidario; sin embargo, una de las deficiencias de estas organizaciones es que no cuentan con herramientas de gestión que coadyuven a la optimización de su liquidez sobre todo en tiempos de crisis, este es el caso de la Asociación de Emprendedores dedicada a la Producción y Comercialización de derivados de lácteos los Campos Andinos, por lo tanto, una manera de lograrlo es diseñando un plan de tesorería para la administración del efectivo. Metodológicamente fue de tipo descriptiva. Los resultados evidencian una deficiente gestión de capital, inadecuado manejo del efectivo, desconocimientos de los niveles de liquidez, entre otros.
Estrategias financieras y contables para el fortalecimiento de la liquidez en la Corporación Agroempresarial Coagro
Authors: Solórzano-Quito Daniela Estefanía , Vásconez-Acuña Lenyn Geovanny 
Published: January 2022

La liquidez representa un pilar fundamental para el desarrollo de las organizaciones, ya que conlleva aspectos relevantes como el cumplimiento de obligaciones en los plazos establecidos, la adquisición de productos y servicios con mejores precios, y negociaciones más eficientes. En este contexto, la situación actual de incertidumbre generada por el COVID – 19 ha hecho evidente el impacto de la crisis mundial sobre la liquidez de las empresas, lo cual se traduce en necesidades urgentes de financiamiento, situación que afecta tanto a organizaciones con problemas de liquidez como aquellas con solvencia financiera. Por lo expuesto, el presente trabajo tiene por objetivo diseñar estrategias financieras y contables para el mejoramiento de la liquidez en la Corporación Agroempresarial Arenillas Coagro. La investigación fue de tipo descriptiva. Los resultados dejaron en evidencia la deficiente planificación financiera, la falta de análisis de información financiera previo a la toma de decisiones, entre otros.
Claves de una buena gestión financiera para mitigar los efectos por pandemia en pequeñas organizaciones
Authors: Rivera-Sarmiento Flavio Gerardo , Erazo-Álvarez Juan Carlos 
Published: January 2022

El plan de acción financiero está encaminado a la mejora de la gestión financiera y la toma de decisiones organizacionales, por lo tanto, se constituye en una herramienta básica sobre todo en tiempos de crisis para dar solución a problemas asociados con la liquidez, endeudamiento y rentabilidad. Por lo expuesto, la investigación tiene por objetivo diseñar un plan de acción financiero para la Asociación Multiservicios Javier Loyola Asomuyola de la ciudad Azogues. El estudio se aplicó bajo una metodología descriptiva. Entre los principales resultados del diagnóstico se determinó los efectos negativos provocados sobre el flujo de efectivo como consecuencia de la pandemia por COVID 19, así como también, afectaciones sobre la cadena de suministro, gestión de cobranza y toma de decisiones. Con base en estos hallazgos, se propone un plan financiero sustentado en estrategias de reactivación económica a aplicarse durante y post-pandemia.
Análisis de riesgos financieros en tiempos de pandemia. Caso Asociación Toquilleras María Auxiliadora
Authors: Tello-Castro Lida Esperanza , Torres-Palacios Mireya Magdalena 
Published: January 2022

La gestión de riesgos involucra una serie de actividades que ayudan a las empresas a diseñar estrategias para la prevención y mitigación de situaciones inesperadas que afectan su desempeño. La pandemia por el Covid-19 ha provocado eventos críticos que aquejan en especial a las pequeñas organizaciones, provocando bajos ingresos, déficit de efectivo y altos niveles de endeudamiento. Por lo tanto, el objetivo de este estudio es diseñar un modelo de medición y gestión de riesgos financieros para mitigar el impacto por endeudamiento en la Asociación de Toquilleras María Auxiliadora. La investigación fue de tipo descriptiva, se aplicó la técnica aplicada de análisis institucional organizacional y la encuesta para el levantamiento de datos. Los resultados evidencian un alto endeudamiento y la necesidad de contar con una herramienta de análisis para mitigar los eventos críticos.
Tradição e imaginário na diplomacia brasileira
Authors: Barreto Pedro Luiz Rodrigues 
Published: January 2022

A diplomacia desempenhou um notório papel na formação histórica do Estado do Brasil. Por essa razão, o patrono da diplomacia brasileira, o Barão de Rio Branco, tornou-se também um dos mais importantes heróis nacionais do país. Como Ministro das Relações Exteriores, Rio Branco foi responsável por conceber as linhas mestras da atuação internacional do Brasil moderno. A partir de sua administração, todo o desenvolvimento da diplomacia brasileira foi definido como a continuação dos postulados e da tradição por ele inaugurados. A relevância e a permanência desse seu legado se deram, a nosso juízo, especialmente por uma singular transformação de ordem simbólica e axiológica que imprimiu ao Itamaraty, transformação essa que lhe confere um inegável prestígio no rol dos estadistas brasileiros. Durante a República, contudo, o ícone histórico do Barão parece ter também se transformado profundamente, assumindo características típicas de uma narrativa mítica. Nesse movimento, a idealização de tal personagem converteu-o em uma espécie de mito fundador da política externa brasileira. A figura mítica de Rio Branco, portanto, é aspecto central de nossa tradição diplomática. À luz dessas considerações, o presente trabalho visa refletir sobre a construção mitológica do Barão de Rio Branco e de seu imaginário diplomático, compreendendo-os como recursos de natureza simbólica e ideológica, que são empregados por nosso Estado Nacional na perseguição de seus interesses estratégicos.
Política criminal petista e sua leitura criminológica (1979-2002)
Authors: Gomes Ícaro Del Rio Pertence 
Published: January 2022

O objetivo deste artigo é debater a política criminal petista (programa que estabelece as condutas que devem ser consideradas crimes e as políticas públicas para sua repressão e prevenção) e a leitura criminológica (apreensão das principais determinantes das condutas criminosas) que a embasa. Para tanto, analisaram-se os documentos redigidos pelo conjunto do partido durante o período de 1979 a 2002. Estes documentos trazem cinco grandes eixos para a questão criminal brasileira: (i) “Criminalidade” urbana; (ii) Crimes políticos rurais; (iii) “Corrupção”; (iv) Criminalização das opressões e (v) Defesa dos direitos humanos e reforma dos aparelhos repressores do Estado. Em linhas gerais, quando lê-se que o crime é uma prática de certa camada privilegiada, o partido denuncia a impunidade sistêmica desses agentes e conclama a apuração e punição destas condutas, criando-se aparatos e reformando os já existentes para tanto. Quando o crime é um “meio anti-social de sobrevivência” das classes espoliadas, compreende-se que a política econômica é a responsável por pressionar os trabalhadores a tais condutas e a proposta principal é elevar as condições materiais dos trabalhadores para que possam sobreviver através de meios lícitos. A exceção a tal tendência são os atos de racismo, machismo e homofobia que atravessam todas as classes sociais. Neste caso, conclama-se a punição destas condutas, ante sua impunidade, bem como a criação de um aparato de proteção do Estado. Por fim, o partido é enfático em defender a reforma do sistema prisional e de todo o aparato repressivo do Estado em defesa dos direitos humanos.
Fabrication and characterization of CH3NH3PbI3 solar cells with added guanidinium and inserted with decaphenylpentasilane
Authors: Ono Iori , Oku Takeo , Suzuki Atsushi , Asakawa Yugo , Terada Shuhei , Okita Masanobu , Fukunishi Sakiko , Tachikawa Tomoharu 
Published: January 2022

Abstract
In this work we investigated the effects of the addition of guanidinium [C(NH2)3; GA] on CH3NH3PbI3 perovskite solar cells fabricated at a high temperature of 190°C in atmospheric air. The addition of GA iodide and the insertion of decaphenylpentasilane between the perovskite and hole transport layer improved the external quantum efficiency and short-circuit current density, and the conversion efficiencies were stable after 1 month. X-ray diffraction showed that the lattice constant of the perovskite crystals was increased by the addition of GA, and addition of GA also improved the surface morphology. First-principles calculations on the density of states and band structures showed reduction of the total energy by the addition of GA and the effectiveness of the nitrogen atoms in GA.
Effects of Ge and Ni catalytic underlayers to nanographene synthesis from pentacene-based film via soft X-ray irradiation
Authors: Heya Akira , Kanda Kazuhiro , Yamasaki Ryo , Sumitomo Koji 
Published: January 2022

Abstract
Herein, carbon films, including pentacene oligomers and pentacene-based precursors, were prepared from pentacene and H2 by hot mesh deposition. Ge and Ni films were used as catalytic underlayers to facilitate the polymerization of the pentacene-based precursors. Thereafter, the hot mesh-deposited C films on the Ge and Ni underlayers were irradiated with soft X-rays of high photon flux density in the NewSUBARU synchrotron facility. The Raman spectra of the Ni underlayer exhibited sharp peaks of the G and D bands, which possibly originated from the nanographene formed after soft X-ray irradiation. Conversely, for the amorphous and the polycrystalline Ge underlayers, broad peaks corresponding to amorphous C or small-sized graphite were observed despite the high-temperature treatment at approximately 1000 °C during soft X-ray irradiation. Results suggest that the differences between the properties of the Ge and Ni underlayers lead to the observed difference in their catalytic activities.
Paesaggi intangibili, voi dite...
Authors: Zagari Franco 
Published: January 2022

... And to think that it is precisely by working remotely that we would have discovered the fascination of absence ...
Intangible landscapes, you say... With this term ‘intangible’ we define some material and immaterial landscapes that are expressions of rights acquired in our history at the price of struggles and sacrifices, whose value we want to preserve because they characterize our identity. As you know, I have always sustained that the substance of the landscape, if understood as a project, has forms and contents that it is not only possible, but dutyful to define, because it is also an eminently political issue, to be proposed to our country as a daily priority commitment.
The effect of different consumption rates of the herbicide Basis, 75, VG, on the level of stress in maize plants
Authors: Storchous I. , Ivaschenko A. , Tyschuk O. 
Published: January 2022

Goal. Establishing the optimally high efficiency of the herbicide Basis, 75, VG, during the control of weed seedlings in maize crops for grain at reduced rates of consumption of the drug to relieve stress in crop plants.
Methods. field; laboratory; quantitative and weight; visual; settlement and comparative; mathematical and statistical.
Results. According to the results of research, it was found that one spraying of crops with herbicide Basis, 75, VG, with the maximum consumption rate allowed, led to the induction of chemical stress in maize plants (determined to reduce the amount of chlorophyll (a + b) from 1.3 to 1.1 g/dm2), which negatively affected the processes of photosynthesis intensity and partially delayed other physiological processes. According to research, it is established that the optimal from both physiological and agronomic assessment is the use of the herbicide Basis, 75, VG, with reduced consumption rates during successive spraying with a time interval, which provided the herbicide in the most sensitive phases of storm germination. and did not lead to the induction of stress in crop plants. According to the obtained indicators, according to the results of research, the highest grain yield was corn at option 3, 8.75 t/ha or 93.9%, where the first spraying of crops with herbicide Basis, 75, VG, with a rate of 12 g/ha + Trend-90 — 0.2 l/ha, during the phase of formation of three leaves in maize plants, and the second spraying on the 4th day after the first spraying.
Conclusions. According to the results of research, a system of application of the herbicide Basis, 75, VG, with reduced consumption rates with a certain time interval between sprays, which eliminates the negative effects of chemical treatment for crops and allows to obtain high yields of corn grain, and the risk of chemical load on the environment 4 to 28%.
ANTIBACTERIAL EFFECTS OF EXTRACTS FROM Tanacetum parthenium L. LEAVES
Authors: Shiferaw Zewditu , Jagathala Mahalingam Sasikumar , Kebede Ameha , Teju Endale 
Published: January 2022

In our current study, phytochemical analysis and antibacterial activity of leaf extracts of T. parthenium were assessed. Qualitative phytochemical screening was carried using standard procedures and quantitative analysis for estimation of total phenolic content (TPC) was determined by spectrophotometric method. The antibacterial activity was accomplished using disc diffusion assay, determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against two gram positives (Streptococcus pyogenes (ATCC 19615), Streptococcus anginosus) and two gram negatives (Pseudomonas aeruginosa (ATCC 27853) and Fusobacterium necrogenes) pathogenic bacteria. Preliminary phytochemical analysis of the plant extracts revealed the presence of phenolics, tannins, flavonoids, terpenoids, and cardiac glycosides. The methanol extract had highest total phenolic content (6.17 ± 0.19 mg/ml). The results also displayed that the methanol extract exhibited significant antibacterial activity against the tested pathogenic microorganisms, in particular against S. anginosus with inhibition zone of 15.33±0.33 mm. The lowest MIC (33.33 mg/ml) and MBC (41.66 g/ml) values were observed in methanol extract against S. anginosus and S. pyogenes respectively. The results indicated that crude leaf extracts of T. parthenium had a potent antibacterial activity suggesting that it could be valuable in treating pathogenic bacterial infections.