bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISI FAKTOR-FAKTOR YANG PENGARUHI PAJAK DAERAH KABUPATEN EKS-KARESIDENAN SURAKARTA
Authors: Gunawan Shodhik Ade , Harimurti Fadjar , Sunarti Sunarti 
Published: September 2022

This study aims to examine the influence and analysis of PDRB, population, inflation and number of industries on the tax revenue of the ex-residency district of Surakarta. This study uses a survey method as an instrument. The population of this study is LKPD and BPS data of the Surakarta Ex-Residency District. Based on the purposive sampling method, the number of samples obtained was 35 data. This type of research used in this research is quantitative research with the aim to uncover the truth contained in this research problem with multiple regression testing and class assumption testing and data analysis to determine the quality used with the help of SPSS 25 software.
The results of this study indicate that partially PDRB variable, Total Population, Inflation and Number of industries affect the Local Tax Revenue. This research is expected to be able to provide useful input for regional governments to synergize with each other to further increase Regional Tax Revenues.
PENGARUH INFLASI, NILAI TUKAR RUPIAH, SUKU BUNGA DAN SELF ASSESSMENT SYSTEM TERHADAP PENERIMAAN PAJAK PERTAMBAHAN NILAI DI KANTOR WILAYAH DIREKTORAT JENDRAL PAJAK JAWA TENGAH II
Authors: Junianto Setiawan , Harimurti Fadjar , Suharno Suharno 
Published: September 2022

Value Added Tax (VAT) is a tax that is imposed on the consumption of goods and services in the customs area. The purpose of this study is to examine the effect of inflation, the rupiah exchange rate, interest rates and self assessment system on value added tax receipts. The population of this study is the inflation rate in Central Java, the exchange rate of the rupiah against one US Dollar based on the tax rate, Bank Indonesia reference interest rate, the number of VAT notification period and all VAT receipts in the Central Java Regional Tax Office
II with monthly data for the 2015- 2019. The data analysis technique used is descriptive analysis, the classic assumption test and the coefficient of determination (R2). The results of the study concluded that inflation and interest rates did not significantly influence VAT revenue, while the rupiah exchange rate and self assessment system had a significant positive effect on VAT revenue.
ANALISIS FAKTOR-FAKTOR YANG MEMENGARUHI PENERAPAN KONSERVATISME AKUNTANSI
Authors: Ridho Muhammad , Arianto Dwi 
Published: September 2022

Penelitian ini bertujuan untuk menguji Faktor-faktor yang memengaruhi konservatisme akuntansi pada perusahaan manufaktur sector makanan di Bursa Efek Indonesia (Periode 2018-2020). Faktor-faktor yang diuji adalah rasio leverage, ukuran perusahaan, intensitas modal, serta kepemilikan manajerial. Penelitian ini menggunakan 15 perusahaan manufaktur sektor makanan yang terdaftar di Bursa Efek Indonesia periode 2018-2020 sebagai sampel penelitian. Pengujian hipotesis menggunakan model analisis regresi 2018-2020 untuk menguji rasio leverage, ukuran perusahaan, intensitas modal, serta kepemilikan manajerial terhadap konservatisme akuntansi. Hasil penelitian menunjukkan bahwa ukuran perusahaan, intensitas modal dan kepemilikan manajerial berpengaruh positif terhadap konservatisme akuntansi, sedangkan rasio leverage berpengaruh negatif terhadap konservatisme akuntansi.

Kata kunci: rasio leverage, ukuran perusahaan, intensitas modal, kepemilikan manajerial.
De Moravia a Buenos Aires: la Presencia de Francisco Latzina en la construcción de sentido y en el origen de la sociología en argentina
Authors: Castiglione Celeste 
Published: September 2022

El presente trabajo busca ofrecer una lectura contextualizada de un fragmento del Censo de 1914 escrito por Francisco Latzina (1843-1922), migrante del Imperio Austro-Húngaro, que formaba parte de la élite política e intelectual que gobernó la Argentina de 1880 a 1916, pero que proyecta su discurso hasta el presente.
En su figura confluyen una multiplicidad de niveles: las corrientes que conforman una Sociología argentina embrionaria, las migraciones tempranas que aportan una construcción étnica e identitaria particular, la formación de cuadros intelectuales que asumen un registro de observación al otro y en este caso específico con el estudio de su muerte se revelan desde su enfoque positivista en toda su contradictoria complejidad.
Repensando y desandando el proceso de investigación en tiempos de virtualidad en contexto de Pandemia
Authors: Heinrich Alejandro , Odetti Verónica Beatriz , Sampietro Juliana 
Published: September 2022

El presente artículo tiene por objetivo presentar una reseña de ciertas dimensiones del proceso metodológico de una investigación realizada en el marco del Estudio nacional sobre las modificaciones en los consumos de sustancias y las respuestas políticas implementadas a partir del Aislamiento Social Preventivo y Obligatorio (ASPO) por COVID-19, llevada a cabo por la cátedra de Psicología Social de la Facultad de Humanidades Artes y Ciencias Sociales de la Universidad Autónoma de Entre Ríos en conjunto con la Secretaría de Políticas Integrales sobre droga de la Nación Argentina (SEDRONAR). Dicha investigación, comprende una revisión, análisis y reflexión del proceso de investigación, las implicancias, desafíos y potencialidades del trabajo remoto en contexto de pandemia durante el 2020.
PENERAPAN MODEL PEMBELAJARAN PROBLEM BASED LEARNING UNTUK MENINGKATKAN KETERAMPILAN BERPIKIR KRITIS KONSEP KALOR PADA SISWA KELAS XI-IPA-1 DAN XI-IPA-2 SMA NEGERI 5 KOTA TERNATE
Authors: Umar Saputri Hi , Balulu Nasrun 
Published: September 2022

Penelitian ini bertujuan untuk mengetahui peningkatan keterampilan berpikir kritis siswa pada konsep kalor dengan menggunakan model pembelajaran Problem Based Learning. Penelitian ini mengikuti rancangan one-group pretest and posttest. Jenis penelitian ini adalah penelitian eksperimen. Metode yang digunakan dalam penelitian ini adalah metode deskriptif kuantitatif. Berdasarkan hasil analisis data, dapat disimpulkan bahwa model pembelajaran Problem Based Learning yang terdiri atas lima sintaks yaitu orientasi, mengorganisasi, investigasi, menyajikan hasil data, dan evaluasi Hasil penelitian menunjukkan bahwa pembelajaran yang dilaksanakan dengan model pembelajaran Problem Based Learning, dapat meningkatkan keterampilan berpikir kritis siswa dengan kategori sedang dan tinggi untuk XI-MIPA-1 dengan rata-rata N-Gain 63.80% dan keterampilan berpikir kritis siswa dengan kategori sedang dan tinggi untuk XI-MIPA-2 dengan rata-rata N-Gain 69.89%. Pengujian normalitas di kelas MIPA-1 diperoleh data 2hit <2tab atau 5,39 < 35,175 dengan dk 23 dan taraf signifikansi (α) 0,05 atau 5%. Maka dapat disimpulkan bahwa data distribusi normal dan Pengujian normalitas di kelas MIPA-2 diperoleh data 2hit <2tab atau 7,06<30,144 dengan dk 19 dan taraf signifikansi (α) 0,05 atau 5%. Dengan demikian Ha ditolak dan Ho diterima. Artinya tidak terdapat perbedaan peningkatan yang signifikan pada penerapan model pembelajaran Problem Based Learning di kelas MIPA-1 dan MIPA-2. Maka dapat disimpulkan bahwa penerapan model pembelajaran Problem Based Learning konsisten dalam penerapannya di kelas.
MENINGKATKAN KEMAMPUAN MEMBACA PEMAHAMAN MENGGUNAKAN STRATEGI KNOW WANT TO LEARN (KWL) PADA SISWA KELAS V SD INPRES 15 HALMAHERA BARAT
Authors: Awa Meike , Abdullah Suhardi , Karim Kodrat Hi. , Marasabesy Anwar 
Published: September 2022

The research objectives consist of (1) To increase students reading comprehension understanding in using Know Want and To Learn strategy and (2) To Describe the students reading comprehension ability in using this teaching strategy by the students of 5th grade SD Inpres Halmahera Barat. Classroom action research has become the kind or type of research that used it. Thus the research consists of planning, action, observation, and reflection. Also, this research used quantitative and qualitative approaches in determining the data analysis. The data considered by the testing process, observation activities (between students and teachers), and also students post-test. The result of both cycles was as follows: (1) the student’s reading comprehension ability score averages at the first cycle were 70 and in the second cycle became 95. It means that the learning strategy functions better in the process and also students’ capability in reading comprehension learning objectives is reached.
Hybrid cell line development system utilizing site-specific integration and methotrexate-mediated gene amplification in Chinese hamster ovary cells
Authors: Min Honggi , Kim Seul Mi , Kim Dongwoo , Lee Solhwi , Lee Sumin , Lee Jae Seong 
Published: September 2022

Site-specific integration has emerged as a promising strategy for streamlined and predictable Chinese hamster ovary (CHO) cell line development (CLD). However, the low specific productivity of the targeted integrants limits their practical application. In this study, we developed a hybrid CLD platform combining site-specific integration of a transgene and dihydrofolate reductase/methotrexate (DHFR/MTX)-mediated gene amplification to generate high-producing recombinant CHO cell lines. We used the CRISPR/Cas9-based recombinase-mediated cassette exchange landing pad platform to integrate the DHFR expression cassette and transgene landing pad into a CHO genomic hot spot, C12orf35 locus, of DHFR-knockout CHO-K1 host cell lines. When subjected to various MTX concentrations up to 1 μM, EGFP-expressing targeted integrants showed a 3.6-fold increase in EGFP expression in the presence of 200 nM MTX, accompanied by an increase in the DHFR and EGFP copy number. A single-step 200 nM MTX amplification increased the specific monoclonal antibody (mAb) productivity (qmAb) of recombinant mAb-producing targeted integrants by 2.8-folds, reaching a qmAb of 9.1–11.0 pg/cell/day. Fluorescence in situ hybridization analysis showed colocalization of DHFR and mAb sequences at the intended chromosomal locations without clear amplified arrays of signals. Most MTX-amplified targeted integrants sustained recombinant mAb production during long-term culture in the absence of MTX, supporting stable gene expression in the amplified cell lines. Our study provides a new CLD platform that increases the productivity of targeted integrants by amplifying the transgene copies.
The guiding value of hybrid resting full-cycle ratio and fractional flow reserve strategy for percutaneous coronary intervention in a Chinese real-world cohort with non-ST elevation acute coronary syndrome
Authors: Lei Yumeng , Zhang Shuaiyong , Li Mengyao , Wang Jiawang , Wang Yunfei , Zhao Lei , Yan Wei , Chen Ming , Su Yanjie , Yu Jing , Yu Na , Dong Tongjun , Cao Xufen , Yan Liqiu 
Published: September 2022

ObjectiveThe study aimed to assess the correlation and agreement between resting full-cycle ratio (RFR) and fractional flow reserve (FFR), and evaluate the guiding value of a hybrid RFR-FFR strategy for percutaneous coronary intervention (PCI) in a Chinese real-world cohort with non-ST elevation acute coronary syndrome (NSTE-ACS).Materials and methodsA total of 109 patients with NSTE-ACS (149 diseased vessels), who underwent an invasive physiological assessment in Cangzhou Central Hospital, Hebei Medical University, were prospectively enrolled from September 2021 to May 2022. FFR ≤ 0.80 was used as the gold standard for coronary artery functional ischemia. We utilized the Pearson correlation and Bland-Altman analysis to assess the correlation and agreement between RFR and FFR. The diagnostic value of RFR predicting FFR ≤ 0.80 was evaluated in accordance with the receiver operating characteristic (ROC) curve. The hybrid RFR-FFR strategy, which was established according to determining the “gray zone” of RFR (FFR was further assessed using vasodilators only for diseased vessels in the “gray zone”), needed to afford over 95% global agreement with the FFR-only strategy.ResultsResting full-cycle ratio was significantly linearly linked with FFR (R2 = 0.636, P &lt; 0.001). The accuracy, specificity, and sensitivity for RFR ≤ 0.89 predicting FFR ≤ 0.80 were 81.2, 70.8, and 86.1%, respectively. The area under the ROC curve for RFR predicting FFR ≤ 0.80 was 0.881 (P &lt; 0.001), and the cutoff value was 0.90. The “gray zone” of RFR was 0.85–0.93. The positive and negative predictive values of the hybrid RFR-FFR strategy were 0.95 and 0.93, respectively. The hybrid RFR-FFR strategy exhibited an agreement of 96.0% with FFR and obviated the need for a vasodilator by 60.4%.ConclusionResting full-cycle ratio and FFR have high correlation and consistency. The hybrid RFR-FFR strategy highlights considerably enhanced agreement with the FFR-only strategy, whilst making the requirement of vasodilator administration less than a half.
OCT angiography analysis of choriocapillaris vascular density in different stages of age-related macular degeneration
Authors: Savastano Maria Cristina , Fossataro Claudia , Carlà Matteo Mario , Fantozzi Chiara , Falsini Benedetto , Savastano Alfonso , Rizzo Clara , Kilian Raphael , Rizzo Stanislao 
Published: September 2022

ObjectivesTo analyze the choriocapillaris vessel density (CVD) of eyes at different stages of Age-related Macular Degeneration (AMD) with Optical Coherence Tomography Angiography (OCTA).MethodsThis is a prospective observational cross-sectional study on 21 age-matched healthy eyes and 84 eyes with AMD (i.e., early AMD, late AMD, Geographic Atrophy [GA], and disciform scar AMD). OCTA was used to automatically measure the CVD (%), on both the whole macula and the foveal area, in a layer going from 9 µm above to 30 µm below the Bruch’s membrane. Furthermore, in the GA subgroup, the extension of the Ellipsoid Zone (EZ) interruption and the area of macular chorio-retinal atrophy was analyzed.ResultsMacular CVD was significantly lower in the GA, late AMD and disciform scar AMD-subgroups compared to controls (respectively, p=0.0052; p&lt;0.0001; p=0.0003), whereas it did not significantly vary in the early AMD group (p=0.86). A significant difference between the early AMD and both the late AMD and the disciform scar AMD subgroups was also found (p=0.0009 and 0.0095, respectively). When comparing the foveal CVD of healthy and AMD eyes, a significant difference was found with every AMD subgroup (early AMD, p=0.011; GA, p&lt;0.0001; late AMD, p&lt;0.0001; disciform scar AMD, p&lt;0.0001). Furthermore, in the GA subgroup, the CVD had an inverse correlation with both the extension of the EZ-interruption (p=0.012) and with the calculated chorio-retinal atrophic area (p=0.009).ConclusionsOCTA could play a crucial role in the categorization of AMD, allowing for the evaluation of gradual flow impairment at different stages of the disease. Moreover, the detection of a decreased macular and foveal CVD may shed light on the pathogenesis of AMD.
Allium stent as a curative treatment for benign ureteral strictures: Preliminary experience, surgical technique, and functional results
Authors: Salciccia Stefano , De Marco Ferdinando , Sciarra Alessandro , Moriconi Martina , Alfarone Andrea , Polese Milena , Maggi Martina , Del Giudice Francesco , Gentilucci Alessandro , De Berardinis Ettore , Ricciuti Gian Piero 
Published: September 2022

ObjectivesTo evaluate the effectiveness and safety of the Allium™ ureteral stent as a curative treatment of benign ureteral strictures.Materials and methodsWe retrospectively reviewed the electronic database of the two centers of patients who underwent ureteral Allium™ positioning for different types of stenosis (benign or malignant). Between April 2017 and May 2021, 151 patients were treated with the Allium™ stent for ureteral strictures including benign and malignant stenosis. In total, 83 of them met the inclusion criteria for benign ureteral stricture and were included in final analysis.ResultsAbout the etiology of strictures, 79 (95.18%) were secondary to ureteroscopy or impacted stones and 4 (4.82%) were secondary to pelvic surgery. The median operating time was 47.9 ± 15.53 min, and the median length of strictures was 2.51 ± 0.84 (1-4) cm. The median time of follow-up was 18 months (range 1–48 months), the overall success rate was 85.5% (71/83), and no intraoperative or perioperative major complications were recorded. Among patients with failure (12 pts, 14.5%): 10 (83.33%) presented ureteral strictures again; among them, 8/10 were patients with a stricture length between 2 and 4 cm, 2 (16.67%) patients with pyelus–ureteral junction stenosis experienced the migration of the stent. All patients who experienced failure were treated surgically either with a robotic or laparoscopic approach.ConclusionsIn our preliminary experience, the Allium™ stent seems to be an effective and safe surgical treatment for benign ureteral stricture. Further analysis and prospective trials are necessary to better define the role of the Allium™ stent in the treatment of benign ureteral strictures.
Hip-preserving reconstruction using a customized cemented femoral endoprosthesis with a curved stem in patients with short proximal femur segments: Mid-term follow-up outcomes
Authors: You Qi , Lu Minxun , Min Li , Zhang Yuqi , Luo Yi , Zhou Yong , Tu Chongqi 
Published: September 2022

BackgroundShort metaphyseal segments that remain following extensive distal femoral tumor resection can be challenging to manage, as the residual short segments may not be sufficient to accept an intramedullary cemented stem of standard length. The present study was developed to detail preliminary findings and experiences associated with an intra-neck curved stem (INCS) reconstructive approach, with a particular focus on mechanical stability.MethodFrom March 2013 to August 2016, 11 total patients underwent reconstructive procedures using a customized cemented femoral endoprosthesis (CCFE) with an INCS. Measurements of femoral neck-shaft angle values were made before and after this procedure. Radiological outcomes associated with this treatment strategy over an average 63-month follow-up period were additionally assessed. Functionality was assessed based upon Musculoskeletal Tumor Society (MSTS) scores, while a visual analog scale (VAS) was used to rate pre- and postoperative pain, and any complications were noted.ResultsRelative to the preoperative design, no significant differences in femoral neck–shaft angle were observed after this reconstructive procedure (p = 0.410). Postoperatively, the tip of the stem was primarily positioned within the middle third of the femoral head in both lateral and posterior-anterior radiographic, supporting the accuracy of INCS positioning. The average MSTS score for these patients was 25 (range: 21–28), and VAS scores were significantly reduced after surgery (p &lt; 0.0001). One patient exhibited local disease recurrence and ultimately succumbed to lung metastases, while two patients exhibited aseptic loosening. None of the treated patients exhibited complications such as infections, periprosthetic fractures, or prosthetic fractures as of most recent follow-up.ConclusionCCFE with an INCS represents a viable approach to massive femoral diaphyseal defect with short proximal femur repair, as patients can achieve good functional outcomes and early weight-bearing with proper individualized rehabilitative interventions, all while exhibiting low rates of procedure-related complications.
Who Said What: A Multi-Country Content Analysis of European Health Organisations’ COVID-19 Social Media Communication
Authors: Kompani Kamyar , Deml Michael J. , Mahdavian Farnaz , Koval Olena , Arora Sanjana , Broqvist Hilda 
Published: September 2022

Objectives: As a risk communication tool, social media was mobilised at an unprecedented level during the COVID-19 pandemic. This study examined health authorities’ risk communication on social media in response to the pandemic in 2020.Methods: We analysed 1,633 COVID-19-related posts from 15 social media accounts managed by official health authorities in Germany, Norway, Sweden, Switzerland, and the United Kingdom.Results: The rate at which the authorities posted about COVID-19 on social media fluctuated throughout 2020. Each account’s posting frequency peaked between March and May 2020, before dropping considerably during the summer. The messages that the organisations focused on also varied throughout the year but covered most risk communication guidelines. Yet, our analysis highlighted themes that were communicated infrequently, such as long COVID or exercising during the pandemic.Conclusion: With more individuals now following health authorities on social media, platforms such as Instagram hold great potential for future risk communication campaigns and strategies.
Home-built environment interventions and inflammation biomarkers: a systematic review and meta-analysis protocol
Authors: Hernandez-Garcia Eva , Chrysikou Evangelia , Nekhlyudov Larissa , Gilroy Derek W , Ordóñez-Mena José M 
Published: September 2022

BackgroundInflammation control is a fundamental part of chronic care in patients with a history of cancer and comorbidity. As the risk–benefit profile of anti-inflammatory drugs is unclear in survivors of cancer, GPs and patients could benefit from alternative non-pharmacological treatment options for dysregulated inflammation. There is a potential for home-built environment (H-BE) interventions to modulate inflammation; however, discrepancies exist between studies.AimTo evaluate the effectiveness of H-BE interventions on cancer-associated inflammation biomarkers.Design & settingA systematic review and meta-analysis of randomised and non-randomised trials in community-dwelling adults.MethodPubMed and MEDLINE, Embase, Web of Science, and Google Scholar will be searched for clinical trials published in January 2000 onwards. The study will include H-BE interventions modifying air quality, thermal comfort, non-ionising radiation, noise, nature, and water. No restrictions to study population will be applied to allow deriving expectations for effects of the interventions in cancer survivors from available source populations. Outcome measures will be inflammatory biomarkers clinically and physiologically relevant to cancer. The first reviewer will independently screen articles together with GPs and extract data that will be verified by a second reviewer. The quality of studies will be assessed using the Cochrane risk-of-bias tools. Depending on the clinical and methodological homogeneity of populations, interventions, and outcomes, a meta-analysis will be conducted using random-effects models.ConclusionFindings will determine the effectiveness of H-BE interventions on inflammatory parameters, guide future directions for its provision in community-dwelling survivors of cancer and support GPs with safer anti-inflammatory treatment options in high-risk patients for clinical complications.