bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unilateral Biportal Endoscopic Tumor Removal and Percutaneous Stabilization for Extradural Tumors: Technical Case Report and Literature Review
Authors: Kim Seung-kook , Bendardaf Riyad , Ali Murtaza , Kim Hyun-a , Heo Eun-jung , Lee Su-chan 
Published: March 2022

Background:Extradural spinal tumors arise from soft or bony tissues in the spine and account for majority of spinal tumors. Interest in the unilateral biportal endoscopic (UBE) technique is rising, because it can easily decompress the bony spinal canal and accommodate all open surgical instruments under endoscopic guidance. However, reports of this technique have been limited to certain diseases. This study first demonstrates the UBE technique for extradural tumor biopsy and removal, and percutaneous stabilization in a 72-year-old female patient with dramatic symptom improvement.MethodsWe used the UBE technique for decompression and the percutaneous screw fixation technique for stabilization in a patient with an extradural mass compressing the thecal sac and destroying the posterior element. Under endoscopic guidance, a unilateral approach was used, and decompression and flavectomy were performed bilaterally. After decompression, tumor removal and biopsy were performed using various forceps and biopsy needles. After confirming sufficient spinal canal decompression, the screw was placed percutaneously. We evaluated the technical process of the procedure, the patient's pre- and postoperative pain (using the visual analog scale), and operative radiology and pathologic results.ResultsPostoperative pain and disability improved clinically, and spinal alignment stabilized radiologically. As the pathology findings confirmed an aneurysmal bone cyst, the treatment was completed without adjuvant therapy.ConclusionsWe treated an unstable spine due to an extradural tumor with the UBE and percutaneous screw techniques.
Advance care planning in primary care for patients with gastrointestinal cancer: feasibility randomised trial
Authors: Canny Anne , Mason Bruce , Stephen Jacqueline , Hopkins Samantha , Wall Lucy , Christie Alan , Skipworth Richard JE , Bowden Joanna , Graham Louise , Kendall Marilyn , Weir Christopher J , Boyd Kirsty 
Published: March 2022

BackgroundAdvance (anticipatory) care planning (ACP) requires discussions between patients and healthcare professionals about planning for future deterioration in health. ACP improves care coordination but uptake is limited and often deferred.AimTo assess the feasibility and acceptability to patients, carers, and GPs of a primary care ACP intervention for people with incurable oesophageal, gastric, or pancreatic cancer.Design and settingA 12-month feasibility randomised controlled trial (RCT) in a Scottish Cancer Network.MethodPatients aged ≥18 years starting palliative oncology treatment were randomised 1:1 to an ACP intervention or standard care. Patients in the intervention group received an oncologist letter supporting them to request a GP review along with a patient information leaflet about ACP. Pre-specified analyses with masking included trial recruitment and retention, ACP completion, and quality-of-life questionnaires (EuroQol EQ-5D-5L and ICECAP Supportive Care Measure) at baseline, 6, 12, 24, and 48 weeks. Qualitative interviews with purposive sampling explored patient, carer, and GP experiences.ResultsOf 99 eligible participants (269 screened), 46% were recruited (n = 46) and randomised; 25 to intervention and 21 to control. By 12 weeks, 45% (n = 9/20) of the individuals in the intervention and 59% (n = 10/17) in the control group had a documented ACP plan. By 24 weeks, 30% (n = 14) had died; in the remaining participants quality of life was maintained at 24 weeks except for physical symptoms. Social norms associating ACP with dying were prevalent among 23 participants interviewed. No psychological or clinical harms were identified.ConclusionAn RCT of ACP for people with incurable cancer in primary care is feasible. Patient, carer, and GP attitudes and behaviours determined acceptability and timing of care planning.
The Clinical Utility of the Neutrophil-to-Lymphocyte Ratio as a Discriminatory Test among Bacterial, Mycobacterium Tuberculosis, and Nontuberculous Mycobacterium Peritoneal Dialysis–Related Peritonitis
Authors: Fung Winston Wing-Shing , Chow Kai-Ming , Ng Jack Kit-Chung , Chan Gordon Chun-Kau , Li Philip Kam-Tao , Szeto Cheuk-Chun 
Published: March 2022

Key Points

Distinguishing Mycobacterium tuberculosis (TB) and nontuberculous Mycobacterium (NTM) from bacterial peritonitis early is often challenging.Delay in diagnosis and treatment of TB/NTM peritonitis often leads to significant morbidity and mortality.The neutrophil-to-lymphocyte ratio is readily calculable, which allows early prompting of TB/NTM peritonitis.

Background
Distinguishing Mycobacterium tuberculosis (TB) and nontuberculous Mycobacterium (NTM) from bacterial peritoneal dialysis (PD)–related peritonitis (peritonitis) is often very challenging and can lead to a significant delay in diagnosis and treatment. The neutrophil-to-lymphocyte ratio (NLR) is readily calculable and has been shown to be useful in differentiating pulmonary TB from bacterial pneumonia. We are the first group to demonstrate the predictive efficacy of peritoneal dialysate (PDE) NLR in distinguishing TB/NTM peritonitis from bacterial causes in the PD population.

Methods
We retrospectively reviewed the clinical and laboratory characteristics of all patients with TB/NTM peritonitis, methicillin-sensitive Staphylococcus aureus (MSSA) peritonitis, and culture-negative peritonitis in our tertiary center between July 2000 and July 2020. The diagnostic ability of the blood and PDE NLR for differential diagnosis was evaluated.

Results
In total, 258 episodes, 38 episodes, and 27 episodes were caused by MSSA, TB, and NTM species, respectively; 364 episodes were culture negative. The PDE NLR level taken at presentation were lowest in the TB peritonitis, followed by the NTM, culture-negative, and MSSA groups, (9.44±13.01, 16.99±23.96, 36.63±32.33, 48.51±36.01; P<0.001, respectively). The area under the receiver operating characteristic curve for the NLR taken at presentation was 0.83 (95% confidence interval, 0.77 to 0.89; P<0.001). A PDE NLR <15 was an optimal cut-off value with sensitivity, specificity, positive predictive value, and negative predictive values of 81%, 70%, 97%, and 22%, respectively.

Conclusions
The PDE NLR obtained at presentation is a useful and easily accessible marker to discriminate TB/NTM peritonitis from bacterial peritonitis, especially in areas with intermediate TB/NTM burden. The NLR may enable early prompting of TB/NTM peritonitis, allowing specific investigation and treatment to be instigated earlier.
Pain Syndrome in the Postoperative Period with the Surgical Treatment of an Oropharingeal Obstruction in the Patients with an Obstructive Apnea Syndrome in the Sleeр
Authors: Макарина-Кибак Л.Э. 
Published: March 2022

Одной из составляющих, характеризующих течение послеоперационного периода, является болевой синдром. В статье представлен обзор литературных данных о механизмах развития боли при хирургическом лечении обструкции верхних дыхательных путей на орофарингеальном уровне. Эффективному купированию болевого синдрома в послеоперационном периоде при операциях в орофарингеальной области посвящено значительное количество работ, но вопрос является нерешенным. Отсутствуют единые подходы к лечению и профилактике его возникновения, необходимо выполнение дальнейших исследований в этом направлении.
One of the components characterizing the course of the postoperative period is the pain. The article presents a review of а literature data on the mechanisms of the pain development in the surgical treatment of an upper respiratory tract obstruction at the oropharyngeal level. A significant amount of the work has been devoted to the effective relief of the pain in the postoperative period during the operations in the oropharyngeal area, but the issue is not resolved. There are no uniform approaches to the treatment and prevention of its occurrence; further studies in this direction are necessary.
The Evaluation of the Eustachian Tube in Patients with Chronic Exudative Otitis Media on the Computerized Tomography
Authors: Гребень Н.И. , Алехно О.В. , Бурчук Н.Ю. , Бибик Р.И. 
Published: March 2022

Выполнен ретроспективный анализ 60 компьютерных томограмм пациентов с диагнозом«хронический экссудативный средний отит» (ХЭСО), проходивших лечение в амбулаторно-поликлиническом отделении РНПЦ оториноларингологии с января 2016 г. по июнь 2019 г. Всего 78 ушей с ХЭСО (18 пациентов с двусторонним ХЭСО и 42 пациента с односторонним ХЭСО). Также в исследование включены 32 компьютерные томограммы пациентов с нормальными ушами (64 уха), выполнивших КТ по другому поводу. Произведена оценка угла «плоскость Рейда – СТ», туботимпанального угла, диаметра претимпанальной части СТ. Толщина среза на КТ-изображении составляла до 1 мм (мультипланарная КТ). Измерения выполнялись двумя врачами и повторены через 2 недели. В результате проведенных измерений у пациентов с ХЭСО на КТ-изображении выявлено в сравнении со здоровыми ушами достоверное уменьшение угла «плоскость Рейда – СТ» (25,53±1,16° к 27,45±1,56°, р<0,01) и диаметра претимпанальной части евстахиевой трубы (5,15±0,56 мм к 6,34±0,47 мм, р<0,01); увеличение туботимпанального угла (147,35±3,25° к 141,57±3,48° в контрольной группе, р<0,01). Таким образом, данные анатомические особенности расположения слуховой трубы могут увеличивать вероятность развития ХЭСО либо способствовать его рецидивированию.
A retrospective analysis of 60 computed tomograms of patients with a diagnosis of “chronic exudative otitis media” who were treated in the outpatient department of the Republican Clinical Center of Otorhinolaryngology since January 2016 until June 2019. In total 78 ears with chronic exudative otitis media (18 patients with bilateral chronic exudative otitis media and 42 patients with unilateral chronic exudative otitis media). The study also included 32 computed tomograms of patients with normal ears (64 ears) who performed CT for another reason. The angle“Reid-ET plane”,the tubotympanal angle, and the diameter of the pretympanal part of the ET are estimated. The slice thickness in the CT image was up to 1 mm (multiplanar CT). Measurements were performed by two doctors and repeated after 2 weeks. As a result of measurements in patients with chronic exudative otitis media on the CT image, a significant decrease in the angle of the “Reid-ET plane”was revealed in comparison with healthy ears (25.53±1.16° to 27.45±1.56°, p<0.01) and the diameter of the pretympanal part of the Eustachian tube (5.15±0.56 mm to 6.34±0.47 mm, p<0.01); increase in the tubotympanal angle of 147.35±3.25° to 141.57±3.48° in the control group, p<0.01). Thus, these anatomical features of the location of the auditory tube can increase the likelihood of developing chronic exudative otitis media or contribute to its recurrence.
Obesity: Current Treatment Options in Adults
Authors: Дыдышко Ю.В. , Шепелькевич А.П. 
Published: March 2022

В статье представлены сведения о распространенности ожирения и избыточной массы тела в различных странах мира с учетом половой принадлежности. Проанализированы современные возможности коррекции избыточной массы тела и при наличии сопутствующей патологии. Описаны подходы немедикаментозной терапии, основанной на модификации образа жизни с формированием привычек рационального питания и расширением адекватной физической активности. Отмечены критерии эффективности и неэффективности терапии. Приведены рекомендации по ведению дневника питания. Проанализированы особенности назначения лекарственных средств, зарегистрированных для лечения ожирения, перечислены противопоказания и вероятные побочные действия. Представлены данные о влиянии гормонов на массу тела с указанием возможных патогенетических механизмов. Описаны типы бариатрических операций, используемые для хирургического лечения ожирения. Указаны рекомендации Российской ассоциации эндокринологов по наблюдению пациентов после радикального лечения.
The article provides information on the prevalence of obesity and overweight in various countries of the world, taking into account gender. The modern possibilities of correction of overweight and obesity are analyzed taking into account concomitant pathologies. The approaches of non- drug therapy based on lifestyle modification with the formation of rational eating habits and the expansion of adequate physical activity are described. The criteria for the effectiveness and ineffectiveness of therapy are noted. Recommendations for maintaining a food diary are given. The features of prescribing drugs registered for the treatment of obesity are analyzed, taking into account contraindications and possible side effects. Data are presented on the effect of hormones on body weight indicating possible pathogenetic mechanisms. The types of bariatric surgery used for the surgical treatment of obesity are described. The recommendations of the Russian Association of Endocrinologists on the observation of patients after radical treatment are indicated.
Acute Complications of Diabetes with COVID-19
Authors: Романовский А.А. , Ярошевич Н.А. , Лущик М.Л. , Радюк Д.В. , Бурко И.И. , Данилова Л.И. 
Published: March 2022

В условиях пандемии коронавируса пациенты с сахарным диабетом входят в группу риска по неблагоприятным исходам COVID-19. Это может быть связано как с наличием хронических осложнений диабета, так и с развитием гипергликемических ком, которые утяжеляют течение инфекции. В настоящее время многие больницы полностью перепрофилированы для лечения исключительно пациентов с COVID-19, где пациентов с сахарным диабетом зачастую лечат не эндокринологи, а врачи других специальностей. Лечение диабетических ком является сложной задачей и в обычных условиях, а ведение пациентов с диабетом и COVID-19 имеет ряд особенностей. Например, при тяжелом течении пневмонии в условиях стационара некоторые пероральные глюкозоснижающие средства необходимо отменять и назначать инсулинотерапию. В связи с этим врачам смежных специальностей необходимо знать не только о последствиях COVID-19 для пациентов с диабетом, но и о принципах лечения острых осложнений сахарного диабета. На амбулаторном этапе основой профилактики диабетических ком является самоконтроль гликемии и своевременная коррекция глюкозоснижающей терапии. При этом улучшение компенсации диабета будет усиливать иммунитет пациента и являться важным фактором, снижающим риск инфицирования вирусом SARS-CoV-2.
In a coronavirus pandemic, patients with diabetes are at risk for adverse outcomes of COVID-19. This may be due to the presence of chronic complications of diabetes, as well as the development of hyperglycemic coma, which aggravate the course of the infection. Currently, many hospitals are completely redesigned to treat exclusively COVID-19, in which patients with diabetes are often treated not by endocrinologists, but by doctors of other specialties. Treatment of diabetic comas is also a difficult task under normal conditions, and the management of patients with diabetes and COVID-19 has a number of features. For example, in severe pneumonia in a hospital setting, some oral glucose-lowering drugs must be canceled and insulin therapy prescribed. In this regard, doctors of related specialties need to know not only about the consequences of COVID-19 for patients with diabetes, but also about the principles of treating acute complications of diabetes. At the outpatient stage, the basis for the prevention of diabetic coma is self-monitoring of glycemia and timely correction of glucose-lowering therapy. At the same time, an improvement in diabetescompensation will enhance the patient’s immunity and be an important factor reducing the risk of infection with the SARS-CoV-2 virus.
Assessment of Young People’s Attitudes Towards Sustainable Entrepreneurship with Machine Learning Techniques Use
Authors: Mroczek Teresa , Kaszuba-Perz Adriana , Czyżewska Marta 
Published: March 2022

RESEARCH OBJECTIVE: The main purpose of the research is to assess whether the young generation in Poland has the potential to build sustainable companies by evaluating the attitudes of university students towards sustainable entrepreneurship..
THE RESEARCH PROBLEM AND METHODS: The readiness to create a sustainable enterprise was assessed on the basis of self-assessment of pro-social attitudes, business intentions and knowledge of social and environmental aspects in business with the use of multidimensional analysis based on machine learning methods.
THE PROCESS OF ARGUMENTATION: A significant challenge for policymakers, scientists and entrepreneurs is solving important social and environmental problems through the development of sustainable entrepreneurship. The implementation of this concept requires efforts to educate and shape pro-social attitudes, especially among the young generation. Therefore, the research focuses on identifying and assessing the attitudes and awareness level of pro-social aspects in business and recognition of entrepreneurial intentions among representatives of this generation.
RESEARCH RESULTS: The research results show that young people have an intuitive sense of what sustainable business is all about, but the formal knowledge in this area is low. Financial aspects, i.e. the possibility of obtaining significant income from own business, as well as independence and the possibility of being a manager, turned out to be much more motivating for entrepreneurship than the possibility of changing the world for the better, helping local communities or protecting the environment.
CONCLUSIONS, INNOVATIONS AND RECOMMENDATIONS: The innovative approach to multidimensional data analysis highlighted the lack of knowledge and insufficient level of pro-social attitudes among the young generation, which is a particularly worrying phenomenon in the context of formulated challenges and social and environmental needs.
Analysis of the Juridical Protection of the Most Traditional Health Laws in the Perspective of the Law of the Republic of Indonesia Number 36 of 2009 Concerning Health
Authors: Razy Fakhruddin , Ariani Malisa 
Published: March 2022

Abstract: In accordance with the ideals of the Indonesian people as referred to in Pancasila and the Preamble of the 1945 Constitution of the Republic of Indonesia that health is a human right and one of the elements of welfare that the state must realize. The government as the holder of the highest power has the authority to achieve the highest possible health status for the community by carrying out comprehensive integrated health efforts. The results showed that Law Number 36 Year 2009 concerning Health has not fully provided legal protection for traditional health service business actors, namely traditional health workers and for traditional health service consumers, namely patients / clients. The hope is that the government should does special legislation regulating traditional health services specifically because traditional health services are currently increasingly diverse in treatment techniques and the more trusted by the Indonesian people.
Pelatihan Pengolahan Sampah Rumah Tangga Di Desa Sigerongan Lingsar Lombok Barat
Authors: Royani Ida , Fitriani Herdiyana , Firdaus Laras , Imran Ali , Nawariah Nawariah 
Published: March 2022

Sampah rumah tangga menjadi salah satu penyumbang masalah sampah di wilayah desa Segerongan. Tujuan Kegitan ini adalah untuk meningkatkan pemahaman dan keterampilan tentang pengolahan sampah rumah tangga di Desa Sigerongan Lingsar Lombok Barat. Mitra dalam kegitan pengabdian ini adalah warga desa Segerongan dengan jumlah angota mitra 20 orang. Metode pelaksanaan pengabdian ini adalah Model Participatory Rapid Appraisal (PRA) dengan tahapan, (1) Persiapan, (2) Pelaksanaan dan (3) Evaluasi. Hasil capaian kegiatan ini adalah peningkatan pemahaman dan keterampilan masyarakat dalam memilah sampah organik dan anorganik serta mampu membuat pupuk organik cair dari sampah rumah tangga degan menggunaan metode komposter. Kegitan pendampingan perlu dilakukan secara kontinu sampai mitra benar-benar bisa mandiri dalam pengelolaan dan pengolahan limbah, selain itu untuk keberlanjutan dibutuhkan manajemen dan wadah seperti bank sampah.
Training On Household Waste Treatment In Sigerongan Lingsar Village West Lombok
Household waste is one of the contributors to the waste problem in the Segerongan village area. The purpose of this activity is to increase understanding and skills regarding household waste processing in Sigerongan Lingsar Village, West Lombok. Partners in this service activity are residents of Segerongan village with 20 partner members. The method of implementing this service is the Participatory Rapid Appraisal (PRA) model with stages, (1) Preparation, (2) Implementation, and (3) Evaluation. The result of this activity is an increase in people's understanding and skills in sorting organic and inorganic waste and being able to make liquid organic fertilizer from household waste using the composter method. Assistance activities need to be carried out continuously until partners can truly be independent in waste management and processing, besides that for sustainability, management and containers such as waste banks are needed.
ANALISIS KINERJA PERAWAT PELAKSANA DALAM PEMBERIASN ASUHAN KEPERAWATAN DI INSTALASI RAWAT INAP
Authors: Suherwin Miming Oxyandi, 
Published: March 2022

ABSTRAKLatar belakang: Kinerja perawat terutama dalam pelaksnaan proses keperawatan masih belum sesuai standar yang ditetapkan. Banyak ditemukan data dilapangan dalam proses pengkajian sampai tahap evaluasi masih banyak yang belum sesuai standar asuhaan keperawatan. Penelitian ini bertujuan: untuk mengidentifikasi dan menganalisi faktor-faktor yang berhubungan dengan penerapan asuhan keperawatan rumah sakit Islam di kota Palembang. Metode penelitian: Desain penelitian yang digunakan adalah observasional dengan pendekatan cross sectional. Populasi penelitian ini berjumalah 83 perawat pelaksana. Penentuan jumlah sampel dalam penelitian ini menggunakan tehnik Proportionate Random Sampling, Besaran sampel dalam penelitian ini sebanyak 68 responden. Hasil penelitian: Hasil penelitian ini secara kumulatif kinerja perawat pelaksana dalam melaksanakan asuhan keperawatan hanya Intervensi keperawatan (75,5%) yang mencapai standar Depkes RI yaitu dengan nilai pencapai 75 %. Ruang VIP, standar kinerja perawat hampir semua dari komponen proses keperawatan memenuhi Standar minimal Depkes 75% (diagnosa sebesar 77%, intervensi sebesar 82%, impelementasi sebesar 78% dan evaluasi sebesar 75%) kecuali komponen pengkajian sebesar 67%. Sedangkan rawat inap biasa sebaliknya didapatkan nilai rata-rata dibawah nilai standar minimal Depkes RI 75% yaitu pengkajian sebesar 58%, diagnosa sebesar 62%, intervensi sebesar 70%, impelementasi sebesar 74% dan evaluasi sebesar 62%. rawat inap intensif didapatkan nilai rata-rata dibawah nilai standar minimal Depkes RI 75% yaitu pengkajian sebesar 64%, diagnosa sebesar 79%, intervensi sebesar 69%, impelementasi sebesar 68% dan evaluasi sebesar 68%. Saran: Penelitian ini merekomendasikan perlu mengembangkan kebijakan terhadap upaya evaluasi penerapan asuhan keperawatan rumah sakit, begitu juga evaluasi terhadap penerapan standar praktek keperawatan serta faktor yang mempengaruhinya. Kata Kunci : Kinerja, Pelaksanaan Asuhan Keperawatan