bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ventral Tegmental Area Glutamate Neurons establish a mu-opioid receptor gated circuit to mesolimbic dopamine neurons and regulate prescription opioid-seeking behavior
Authors: McGovern Dillon J. , Polter Abigail M. , Ly Annie , Prevost Emily D. , McNulty Connor , Root David H. 
Published: December 2022

ABSTRACTA two-neuron model of ventral tegmental area (VTA) opioid function classically involves VTA GABA neuron regulation of VTA dopamine neurons via a mu-opioid receptor dependent inhibitory circuit. However, this model predates the discovery of a third major type of neuron in the VTA: glutamatergic neurons. We find that about one-quarter of VTA neurons expressing the mu-opioid receptor are glutamate neurons without molecular markers of GABA co-release. Glutamate-Mu opioid receptor neurons are topographically distributed in the anterior VTA. The majority of remaining VTA mu-opioid receptor neurons are GABAergic neurons that are largely within the posterior VTA and do not express molecular markers of glutamate co-release. Optogenetic stimulation of VTA glutamate neurons results in monosynaptic excitatory currents recorded from VTA dopamine neurons that are reduced by presynaptic activation of the mu-opioid receptorex vivo, establishing a local mu-opioid receptor dependent excitatory circuit from VTA glutamate neurons to VTA dopamine neurons. This VTA glutamate to VTA dopamine pathway regulates dopamine release to the nucleus accumbens through mu-opioid receptor activityin vivo. Behaviorally, VTA glutamate calcium-related neuronal activity increased following oxycodone consumption and response-contingent oxycodone-associated cues during self-administration and abstinent reinstatement of drug-seeking behavior. Further, chemogenetic inhibition of VTA glutamate neurons reduced abstinent oxycodone-seeking behavior in male but not female mice. These results establish 1) a three-neuron model of VTA opioid function involving a mu-opioid receptor gated VTA glutamate neuron pathway to VTA dopamine neurons that controls dopamine release within the nucleus accumbens, and 2) that VTA glutamate neurons participate in prescription opioid-seeking behavior.
Examining the Role of Maternal Religiosity in Offspring Mental Health Using Latent Class Analysis in a UK Prospective Cohort Study
Authors: Halstead Isaac , Heron Jon , Svob Connie , Joinson Carol 
Published: December 2022

AbstractBackgroundPrevious research has examined the role of parental religious belief in offspring mental health, but has revealed inconsistent results, and suffered from a number of limitations. The aim of this study is to examine the prospective relationship between maternal religiosity and offspring mental health and psychosocial outcomes.MethodsWe used latent classes of religious belief (Highly religious, Moderately religious, Agnostic, Atheist) in mothers from the Avon Longitudinal Study of Parents and Children and examined their association with parent-reported mental health outcomes and self-reported psychosocial outcomes in their children at age 7-8 (n = 6079 for mental health outcomes and n = 5235 for psychosocial outcomes). We used inverse probability weighted multivariable logistic regression analysis adjusted for maternal mental health, adverse childhood experience, and socioeconomic variables.ResultsThere was evidence for a greater risk of internalising problems among the offspring of the Highly religious and Moderately religious classes (e.g. for depression; OR = 1.51, 95% CI [1.24,1.77], OR = 1.50, 95% CI [1.26,1.73]), and greater risk of externalising problems in the offspring of the Atheist class (e.g. for ADHD; OR = 1.44, 95% CI [1.18,1.71]), compared to the offspring of the Agnostic class.ConclusionsThese novel findings provide evidence associations between maternal religiosity and offspring mental health differ when examined using a person-centred approach, compared to the previously used variable-centred approaches. Our findings also suggest that differences may exist in the relationship between religious (non)belief and mental health variables when comparing the UK and US.
Does female off-farm employment affect fertility desire? Evidence from rural China
Authors: Shen Zheng , Brown Derek S. , Yu Kang 
Published: December 2022

PurposeOff-farm employment is an important factor associated with fertility transition in many developing countries. The purpose of this paper is to investigate the impact of female off-farm employment on their fertility desire in rural China.Design/methodology/approachBased on the data from the China Labor-force Dynamics Survey, the authors adopt an instrumental variable approach to address the endogeneity issue. Desired number of children and desire for a second child are used to measure fertility desire.FindingsThe results show that off-farm employment participation significantly reduces women's desired number of children and the likelihood of their desire for a second child. Moreover, off-farm employment reduces women's fertility desire mainly through pathways including the weakening of son preference and a decrease in job autonomy, rather than the changes in leisure hours. Further evidence suggests that social health insurance plays an important role in moderating the adverse relationship between off-farm employment and the desire for a second child. The fertility-reducing effects are more pronounced among younger women, among those participating in off-farm wage employment and among families with only wives' participation in the off-farm labor market.Originality/valueThis paper contributes to the existing research by investigating the causal impact of off-farm employment on fertility desire in a rural developing context and the possible underlying mechanisms responsible for this relationship. This study provides important insights on this topic in developing countries and may have important implications for theory and practice.
Policy framework to apply artificial intelligence for the management of records at the Council for Scientific and Industrial Research
Authors: Modiba Mashilo 
Published: December 2022

Purpose
This study aims to investigate how a policy framework can be applied in the use of artificial intelligence (AI) for the management of records at the Council for Scientific and Industrial Research (CSIR) in South Africa. A policy and legal framework enables the records divisions to protect, administer and make their records available in a safe and professional way. Policies play a crucial role in ensuring that records are properly managed.

Design/methodology/approach
Convergent mixed-methods research was conducted, and data were collected using interviews and questionnaires. Data were analysed thematically and statistically and presented in tables and figures.

Findings
The study reveals that the policy framework should also include the application of AI for the management of records. Therefore, this study further concludes that the CSIR should review their policy framework to ensure the application of AI for the management of records is accommodated.

Originality/value
The study proposed a framework to guide the application of the policy framework in using AI for the management of records at CSIR. It is hoped that the proposed framework will serve as a guideline for the implementation of a policy framework in the utilisation of AI in the archives and records management sector.
Advertising of a national importance the Swedish Advertisers’ Association and the institutionalization of Sweden's international advertising 1955–1972
Authors: Funke Michael 
Published: December 2022

Purpose
The purpose of this paper is to analyze the Swedish Advertisers’ Association's role in the institutional development of Swedish international advertising during 1955–1972.

Design/methodology/approach
A qualitative analysis of business association sources is used to explore the institutional development of international advertising.

Findings
A new postwar paradigm that focused on a consumer-oriented brand ideology enabled marketing executives in the Swedish Advertisers’ Association to develop a new discourse on international advertising in Sweden, which then was institutionalized within a national network on export promotion. The institutionalization process was supported by a corporatist system typical of smaller export dependent postwar European economies.

Research limitations/implications
While based on a national case, this study points to the importance of understanding how advertising concepts are embedded within other economic, political and cultural systems than in those they originated in and how this contributes to a heterogenous implementation of similar ideas and practices. This study also illustrates how members can use their association to institutionalize a new discourse on marketing and network with other actors to enhance the use and reputation of its ideas and practices.

Practical implications
By highlighting the importance of analyzing both internal and external organizational relations, this study contributes to the research on history of marketing by making salient the importance of an institutional perspective to understand key processes in marketing. In practice neither the institutional perspective nor the explanatory power of discourse has received much attention, therefore the study results should be both interesting and valid for practitioners as well.

Originality/value
The study of the historical development of international advertising is limited and often descriptive. This study contributes to the literature by using a theoretical and methodological approach to make salient how the interaction between discourse, marketing associations and other collective actors propelled the institutionalization of international advertising within a specific national context.
How an industrial internet platform empowers the digital transformation of SMEs: theoretical mechanism and business model
Authors: Li Honglei , Yang Ziyu , Jin Chunhua , Wang Jinxia 
Published: December 2022

Purpose
The purpose of this paper is to reveal the inner mechanisms of the role of industrial internet platforms in empowering the digital transformation of SMEs. This ROOTCLOUD-based case study shows that knowledge integration and knowledge sharing and driving play essential empowering roles in the impact of industrial internet platforms on the digital transformation of SMEs. The industrial internet platform promotes knowledge integration on the supply side, empowers cross-domain knowledge sharing and shapes the knowledge-driven digital supply chain system in the digital transformation processes of SMEs.

Design/methodology/approach
This paper presents a qualitative analysis of the knowledge empowerment role played by industrial internet platforms in the digital transformation process of SMEs. Based on theoretical sampling, this paper selects ROOTCLOUD as a typical case to analyse the implementation mechanism of the industrial internet platform in solving the digital transformation problems and challenges faced by SMEs.

Findings
Knowledge management (knowledge integration, sharing and driving) plays an important intermediary role between the empowerment of industrial internet platform and the digital transformation of SMEs. Specifically, the industrial internet platform empowers SMEs with knowledge, empowers supply-side knowledge integration, empowers cross-domain knowledge sharing and facilitates the formation of knowledge-driven supply chain systems.

Research limitations/implications
This study clarifies the mechanism underlying the digital transformation of SMEs empowered by industrial internet platforms, that is, the empowerment of industrial internet platform enhances the level of knowledge integration and sharing of SMEs, thus improving the effectiveness of SMEs in achieving digital transformation. Further empirical studies should be conducted on the above mechanism.

Originality/value
Based on the theoretical perspective of knowledge management, this paper discusses the problems and challenges faced in the digital transformation of SMEs through knowledge empowerment by the industrial internet platform ROOTCLOUD and proposes that knowledge empowerment in the industrial internet platform helps supply-side knowledge integration, promotes cross-domain knowledge sharing and contributes to forming a knowledge-driven supply chain system, thereby promoting the digital transformation of SMEs. System architects and relevant policy departments should pay attention to data-centred system construction, improve the construction of data-based collaborative application ecology and encourage industrial internet platforms to provide more targeted knowledge empowerment solutions for SMEs.
Exploring the tourism development strategies of Gulf Cooperation Council countries: commonalities, contrasts and clusters
Authors: Mahate Ashraf A. , Parahoo Sanjai K. 
Published: December 2022

PurposeThis study aims to examine the commonalities and contrasts in the tourism objectives and strategies of the Gulf Cooperation Council (GCC) countries, thereby revealing the foundations and pillars underlying the strategic initiatives implemented.Design/methodology/approachThis exploratory study applied the resource-based view (RBV) lens to the country level. A comparative analysis of the tourism strategy in each GCC country was undertaken to determine commonalities and contrasts between the different strategies and to classify them into clusters. In the next stage, in-depth interviews were carried out to validate the findings.FindingsFour distinct clusters were identified in this paper: lifestyle glamor, emerging giant, sports-induced country branding and eco-friendly regional-based strategies.Practical implicationsThe findings and cluster classification are pertinent to policymakers and industry marketers in crafting tourism development plans.Originality/valueThis study analyzed the economic diversification strategies adopted by GCC countries as new entrants in the tourism sector and classified them into four clusters.
3D printing of microbial communities: A new platform for understanding and engineering microbiomes
Authors: Krishna Kumar Ravinash , Foster Kevin R. 
Published: December 2022

Abstract3D printing has emerged as a powerful way to produce complex materials on‐demand. These printing technologies are now being applied in microbiology, with many recent examples where microbes and matrices are co‐printed to create bespoke living materials. Here, we propose a new paradigm for microbial printing. In addition to its importance for materials, we argue that printing can be used to understand and engineer microbiome communities, analogous to its use in human tissue engineering. Many microbes naturally live in diverse, spatially structured communities that are challenging to study and manipulate. 3D printing offers an exciting new solution to these challenges, as it can precisely arrange microbes in 3D space, allowing one to build custom microbial communities for a wide range of purposes in research, medicine, and industry.
Consequences of local social norms: A review of the literature in accounting, finance, and corporate governance
Authors: Habib Ahsan , D' Costa Mabel , Al‐Hadi Ahmed Khamis 
Published: December 2022

AbstractWe synthesise the empirical archival research on the consequences of local social norms on accounting, finance, and corporate governance outcomes in an international setting. The literature reviewed is premised on the theory that corporations do not make decisions, but managers do, and managers are likely to be influenced by the socioeconomic environment of the region in which they operate and/or by the people with whom they interact. To provide a structure to our review, we identify social capital, religiosity, gambling norms, and corruption culture, as four constructs of local social norms and link these with financial reporting and external auditing, financial, investment, and dividend decisions, capital market consequences and finally, corporate governance and corporate social responsibility behaviour of firms. We highlight some limitations of the existing research and offer some suggestions for future research.
Advance planning for research participation: Time to translate this innovation into practice
Authors: Ries Nola , Johnston Briony , Jeon Yun‐Hee , Mansfield Elise , Nay Rhonda , Parker Deborah , Schnitker Linda , Sinclair Craig 
Published: December 2022

AbstractObjectivesAdvance planning for research is a process that involves thinking about, discussing and expressing preferences for taking part in research during future periods of incapacity. The process may include making an advance research directive and naming trusted people to be involved in decisions about research participation. Advance research planning could help to overcome barriers to including people with dementia in research. To encourage innovation in this area, this article presents recommendations informed by a stakeholder workshop that brought together consumer representatives and representatives active in dementia, ageing and health‐related research, policy‐making, advocacy and service delivery in health and aged care.MethodsAn online workshop where 15 stakeholders shared perspectives and suggestions for implementing advance research planning, with a focus on research involving people with dementia.ResultsRaising awareness of advance research planning requires multi‐faceted strategies. Training and resources are needed for researchers, ethics committees and organisations regarding this form of advance planning and the use of research directives. Like any form of advance planning, planning ahead for research must be a voluntary, informed and person‐centred process. There is a lack of uniform legal rules on research involving people who lack the capacity to consent; however, advance research directives could, in principle, inform decisions about research participation.ConclusionsAs a matter of law, policy and practice, people are encouraged to plan ahead in many areas of their life. Research planning has been relatively neglected, and the recommendations offered here aim to encourage innovation in research and implementation in this area.
Transition from open to robotic distal pancreatectomy in a low volume pancreatic surgery country: a single Australian centre experience
Authors: Masuda Hiro , Kotecha Krishna , Gall Tamara , Gill Anthony J. , Mittal Anubhav , Samra Jaswinder S. 
Published: December 2022

AbstractBackgroundAdvances in technology and techniques have allowed for robotic distal pancreatectomies to be readily performed in patients at high volume centres. This study describes the experience of a single surgeon during the learning curve and transition from open to robotic distal pancreatectomy in Australia, a traditionally low volume pancreatic surgery country.MethodsAll patients undergoing distal pancreatectomy at an Australian‐based tertiary referral centre between 2010 and 2021 were reviewed retrospectively. Demographic, clinicopathologic and survival data were analysed to compare perioperative and oncological outcomes between patients who underwent open, laparoscopic and robotic distal pancreatectomies.ResultsA total of 178 distal pancreatectomies were identified for analysis during the study period. Ninety‐one open distal pancreatectomies (ODP), 48 laparoscopic distal pancreatectomies (LDP), and 39 robotic distal pancreatectomies (RDP) were performed. Robotic distal pancreatectomy was non‐inferior with respect to perioperative outcomes and yielded statistically non‐significant advantages over LDP and ODP.ConclusionRDP is feasible and can be performed safely in well‐selected patients during the learning phase at large pancreatic centres in a traditionally low‐volume country like Australia. Referral to large pancreatic centres where access to the robotic platform and surgeon experience is not a barrier, and where a robust multidisciplinary team meeting can take place, remains pivotal in the introduction and transition toward the robotic approach for management of patients with pancreatic body or tail lesions.
Functional outcomes after single quadriceps muscle resection in patients with soft tissue sarcoma of the anterior compartment of the thigh
Authors: Gu Xinchen , Ricketts Sophie , Mah Eldon 
Published: December 2022

AbstractBACKGROUNDSoft tissue sarcoma (STS) occurs most commonly in the anterior compartment of the thigh. Limb salvage surgery is the mainstay of treatment, however, resections frequently involve muscle sacrifice. This study determines the impact of a single quadriceps muscle sacrifice on daily living functions. This is to assist clinical decision‐making relating to when a functional reconstruction should be offered over simple soft tissue coverage for these defects.METHODSPatients who underwent single quadriceps resection as part of the management of STS between 2010 and 2020 were selected. Three functional tests were performed: Time Up and Go (TUG), Timed Up and Down Stairs (TUDS) and Toronto Extremity Salvage Score (TESS). The results were compared with age/sex matched healthy reference values and literature cohorts of lower limb STS patients. Correlations between the tests and age and follow‐up duration were determined by the Spearman's test.RESULTSThe mean TESS, TUG and TUDS results of the 13 patients were 89.6%, 9.8 and 1.01 s/step, respectively. These scores were either similar or significantly better than the comparator values. The TESS score showed no statistical significance compared with patients with no muscle resection. TUG and TUDS scores showed significant positive correlation with each other (ρ = 0.885, P = <0.01) and with age (ρ = 0.646, P = 0.017 and ρ = 0.567, P = 0.043, respectively).CONCLUSIONThis is the largest documented case series of single quadriceps resection for STS. The study suggests that this group of patients does not show a functional deficit and therefore does not require functional reconstruction.
Bayesian Sample Size Calculations for Comparing Two Strategies in SMART Studies
Authors: Turchetta Armando , Moodie Erica E. M. , Stephens David A. , Lambert Sylvie D. 
Published: December 2022

Abstract
In the management of most chronic conditions characterized by the lack of universally effective treatments, adaptive treatment strategies (ATSs) have grown in popularity as they offer a more individualized approach. As a result, sequential multiple assignment randomized trials (SMARTs) have gained attention as the most suitable clinical trial design to formalize the study of these strategies. While the number of SMARTs has increased in recent years, sample size and design considerations have generally been carried out in frequentist settings. However, standard frequentist formulae require assumptions on interim response rates and variance components. Misspecifying these can lead to incorrect sample size calculations and correspondingly inadequate levels of power. The Bayesian framework offers a straightforward path to alleviate some of these concerns. In this paper, we provide calculations in a Bayesian setting to allow more realistic and robust estimates that account for uncertainty in inputs through the ‘two priors’ approach. Additionally, compared to the standard frequentist formulae, this methodology allows us to rely on fewer assumptions, integrate pre-trial knowledge, and switch the focus from the standardized effect size to the MDD. The proposed methodology is evaluated in a thorough simulation study and is implemented to estimate the sample size for a full-scale SMART of an internet-based adaptive stress management intervention on cardiovascular disease patients using data from its pilot study conducted in two Canadian provinces.