bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationships between the shape of the hoof capsule and orientation of the distal phalanx in long toe underrun heels in donkeys
Authors: El‐Marakby Ahmed , Abdelgalil Ahmed , Mostafa Mohamed , Soliman Ahmed 
Published: October 2022

SummaryBackgroundThere is limited information on the morphology, radiography and orientation of the distal phalanx in the hoof capsule in long toe underrun heels in donkeys.ObjectivesThis study aimed to determine the relationships between the hoof capsule shape and distal phalanx radiographic parameters.Study designPost‐mortem collected feet.MethodsA total of 68 cadaver front hooves with long toe underrun heels were used in the study. Lateral photographic and lateromedial radiographic parameters of the feet were obtained.ResultsThe mean hoof wall angle (HWA) was strongly significantly correlated with heel angle (HA), dorsal HWA, HA measured through radiography and distal phalanx to toe distance and was modestly correlated with distal phalanx angle, solar border of the distal phalanx angle, coronet angle and distal phalanx to frog distance. The linear hoof wall length (HWL) and heel length showed a strong and modest significant correlation with distal phalanx to bottom, dorsal HWL and distal phalanx to toe distance.Main limitationsThe feet included in the study were obtained from many yards and different body sizes.ConclusionsThis study supports an association between radiographic and morphologic parameters in long toe underrun heels. The strong and modest correlations between measured photographic and radiographic parameters may indicate the relationships between the hoof capsule shape and distal phalanx orientation.
Influence of artificial seawater on the VHCF behavior of different steels
Authors: Wickmann Carsten , Sander Manuela 
Published: October 2022

AbstractThe fatigue properties of a high‐strength steel, a structural steel, and a duplex stainless steel in artificial seawater were investigated. Consequently, a test chamber for the existing ultrasonic test stand was implemented. The experiments were performed with smooth specimens at a loading with R = −1 up to 2 · 109 cycles. The specimens were fully submerged in artificial seawater. The fatigue data were statistically evaluated using the pearl string method and compared to different SN curves from the literature in air. The results show continuously decreasing SN curves under seawater conditions for all materials, with no detectable fatigue limit. Fracture surface investigations reveal large corrosion areas for the structural steel with, generally, no clear crack initiation location. The duplex stainless steel shows less corrosion pits but a high degree of scatter of the SN data. For the high‐strength steel, multiple crack initiation locations were observed from the surface.
The effect of a virtual child disease management programme on burden and social adjustment of caregivers of children with coagulation factor deficiencies
Authors: Rambod Masoume , Pasyar Nilofar , Irannejad Parizi Fatemeh , Edraki Mitra , Khair Kate , von Mackensen Sylvia 
Published: October 2022

AbstractIntroductionThe use of virtual interventions is of interest to patients with chronic disease and healthcare professionals. This study aimed to determine the effect of virtual child disease management programme on burden and social adjustment of caregivers of children with coagulation factor deficiencies. Moreover, the effect of this intervention on children's acute pain and bleeds was assessed.MethodsThis clinical trial was conducted on 80 caregivers of children with coagulation factor deficiencies. The subjects were randomly assigned into the intervention and control groups. A comprehensive virtual child disease management programme was conducted for 8 weeks and caregiver’ burden and their social adjustment were assessed with the HEMOCAB and social adjustment subscale of Bell Adjustment Inventory, respectively. Data were analysed using ANCOVA and Wilcoxon test.ResultsBefore the intervention, both groups were similar regarding the caregivers’ burden and social adjustment and children's acute pain and bleeds. However, a significant difference was observed between groups in concern to caregivers’ burden (P < .001), women's and men's social adjustment (P = .001, P = .03), and children's acute pain and bleeds (P < .001) after the virtual disease management programme.ConclusionThis study showed that using a virtual child disease management programme reduced burden and improved social adjustment of caregivers of children with coagulation factor deficiencies. This intervention decreased frequencies of acute pain and bleeds in children. Therefore, using this effective intervention in clinical practice is warranted to decrease the caregivers’ burden as well as acute pain and bleeds in children.
180‐degree immersive VR motion visualization in the treatment of haemophilic ankle arthropathy
Authors: Ucero‐Lozano Roberto , Pérez‐Llanes Raúl , López‐Pina José Antonio , Cuesta‐Barriuso Rubén 
Published: October 2022

AbstractBackgroundPatients with haemophilic arthropathy suffer chronic pain that affects and restricts their quality of life. Visualization of movement through immersive virtual reality is used for pain management.AimTo evaluate the efficacy of 180‐degree immersive VR motion visualization therapy in patients with haemophilic ankle arthropathy.MethodsProspective, multicentre pilot study. Fifteen adult patients with bilateral haemophilic ankle arthropathy were recruited (mean age: 42.73 ± 12.36 years). The intervention lasted 4 weeks, with daily home sessions of 180‐degree immersive motion visualization. The patients were given virtual reality glasses to use with their smartphones. From the YouTube mobile app® they accessed the recorded video with access from the He‐Mirror App®. The study variables were joint state (Haemophilia Joint Health Score), pressure pain threshold (pressure algometer), muscle strength (dynamometry) and range of motion (goniometry). Three evaluations were performed: at baseline (T0), after the intervention (T1) and at the end of a 16‐week follow‐up period (T2).ResultsNo patient developed ankle hemarthrosis during the experimental phase. In the repeated measures analysis we found statistically significant differences in joint state (F = 51.38; η2p = .63), pressure pain threshold of the lateral malleolus (F = 12.34; η2p = .29) and range of motion (F = 11.7; η2p = .28).ConclusionsTherapy using immersive motion visualization does not cause hemarthrosis. This intervention can improve joint condition, pressure pain threshold and range of motion in patients with ankle arthropathy. Changes greater than the MDC were reported in more than 40% of patients for the variables pressure pain threshold, anterior tibialis strength and range of motion, which were considered clinically relevant.
Inhibition of acrylamide and 5‐hydroxymethylfurfural formation in French fries by additives in model reaction
Authors: Verma Vandana , Yadav Neelam 
Published: October 2022

AbstractAcrylamide (AA) and 5‐hydroxymethylfurfural (HMF) are Maillard reaction products that are formed during frying; they are toxic and are considered a potential health risk due to their high consumption levels in western diets. The purpose of this study was to evaluate various strategies for the formation of AA and HMF in French fries. HMF was quantified with a UV‐spectrophotometer and AA was determined by high‐pressure liquid chromatography (HPLC) with the help of diode array detection (DAD) detector. Principal component analysis was used to visualize the effects of the various additive treatments, and these data were also used to evaluate the best‐fitting regression models between AA and HMF with reducing sugar, asparagine, and color value (a*), and browning index. The resulting models showed a highly significant correlation (r > 0.90, p < 0.001). Organic acids and salts and pectin all significantly reduced the final AA content due to the change in pH. Additionally, amino acids decreased AA while maintaining the pH at its original value. With a combination of citric acid and l‐lysine, a synergistic AA‐lowering effect was observed.Practical applicationThis research will benefit the Indian food industry by demonstrating how an additive can be used as a pretreatment to compress the AA and HMF content of foods. This frequently raises the customer's awareness of consumable goods and the importance of determining the maximum amount that can be consumed daily to protect themselves from contaminants such as HMF and AA.
Longitudinal patterns and predictors of self‐care behavior trajectories among Korean patients with heart failure: A 6‐month prospective study
Authors: Kim Da‐Young , Son Youn‐Jung 
Published: October 2022

AbstractPurposeThis study aimed to identify distinct trajectories of self‐care behaviors over 6 months after hospital discharge in patients with heart failure, including the baseline predictors affecting these trajectories.DesignThis was a prospective longitudinal observational cohort study with a 6‐month follow‐up.MethodsA total of 158 patients with heart failure (mean age = 66.75 years, 62.7% men) were included in this study. Patients' characteristics, including cognitive function, health literacy, and social support were collected as possible baseline predictors of self‐care behavior trajectories using a structured questionnaire and an electronic medical record review. Self‐care behaviors were evaluated using the Korean version of the nine‐item European Heart Failure Self‐care Behavior Scale at baseline, 1, 3, and 6 months after hospital discharge. Latent growth model analysis was conducted to identify the homogeneous subgroups with distinct trajectories of self‐care behaviors. Subsequently, multinomial logistic regression was used to assess whether baseline predictors were associated with these trajectories in patients with heart failure.ResultsThree distinct self‐care behavior trajectory groups were identified: “low‐decreased” (n = 33, 20.9%), “middle‐increased” (n = 93, 58.9%), and “high‐sustained” (n = 32, 20.2%). The multinomial logistic regression analysis showed that baseline adequate health literacy and positive social support significantly predicted patients' belonging to both the middle‐increased and high‐sustained self‐care behavior trajectory groups compared to the low‐decreased group. Importantly, better cognitive function at baseline was only significantly associated with the high‐sustained self‐care behavior trajectory compared to the low‐decreased trajectory.ConclusionOur study revealed that only one‐fifth of the patients belonged to the high‐sustained self‐care behavior group 6 months after hospital discharge. Strategies aimed at improving cognitive function, health literacy, and social support should be developed to sustain satisfactory self‐care behaviors in patients with heart failure. Further studies with long‐term follow‐ups are required to identify other possible factors, as well as the baseline predictors of this study affecting longitudinal trajectories of self‐care behaviors.Clinical relevanceHealthcare providers should recognize and evaluate the distinct patterns of self‐care behaviors over time in patients with heart failure. Importantly, assessing baseline cognitive function, health literacy, and social support before hospital discharge may be necessary to prevent a decline in self‐care behaviors over time.
Oral lesions in patients with human monkeypox: A systematic scoping review
Authors: Ardila Carlos M. , Arrubla‐Escobar Daniel Esteban , Vivares‐Builes Annie Marcela 
Published: October 2022

AbstractObjectivesTo describe the clinical features and location of oral lesions in patients with human monkeypox.MethodsA systematic scoping review was accomplished by implementing the Preferred Reporting Items for Systematic Reviews and Meta‐analyses extension for scoping reviews. The analysis incorporated varied databases and the gray literature. Keywords were implemented to search publications in all languages until July 2022.ResultsThe initial electronic exploration included 889 reports, of which 843 studies were eliminated. Reading the full text occasioned the omission of 27 additional investigations. Finally, 19 publications were included. These reports analyzed 1256 patients with monkeypox, mostly described in Europe. Most of them were men who have sex with men. The study population consisted mainly of adults but children were also infected. The oral lesions of monkeypox patients were observed in different parts of the oral mucosa, including lips and tongue, but mainly in the tonsils (15 cases). The oral lesions manifested as papules, vesicles, pustules, and ulcers. Erythema, edema, enanthema, and severe pain were also observed, accompanied by tonsillar enlargement. Sore throat was also reported. Monkeypox is accompanied by a significant number of systemic manifestations, mainly including multiple skin lesions throughout the body, as well as lymphadenopathy, fever, headache, myalgia, and fatigue, among others. The symptoms associated with monkeypox were managed with different antiretroviral and antimicrobial therapies and medications to control pain and fever principally. Seventeen deaths were informed.ConclusionMost monkeypox‐associated oral lesions are seen in different parts of the oral mucosa, mainly in the tonsils manifested as papules, vesicles, pustules, and ulcers.
Landscape genetics across the Andes mountains: Environmental variation drives genetic divergence in the leaf‐cutting ant Atta cephalotes
Authors: Muñoz‐Valencia Vanessa , Montoya‐Lerma James , Seppä Perttu , Diaz Fernando 
Published: October 2022

AbstractDistinguishing among the mechanisms underlying the spatial distribution of genetic variation resulting from the environmental or physical barriers from those arising due to simple geographic distance is challenging in complex landscapes. The Andean uplift represents one of the most heterogeneous habitats where multiple mechanisms may interact, confounding their relative roles. We explore this broad question in the leaf‐cutting ant Atta cephalotes, a species that is distributed across the Andes mountains, using nuclear microsatellite markers and mtCOI gene sequences. We investigate spatial genetic divergence across the western range of the northern Andes in Colombia by testing the relative role of alternative scenarios of population divergence, including isolation by geographic distance (IBD), climatic conditions (IBE), and the physical barriers presented by the Andes mountains (IBB). Our results reveal substantial genetic differentiation among A. cephalotes populations for both types of markers, but only nuclear divergence followed a hierarchical pattern with multiple models of genetic divergence imposed by the western range. Model selection showed that the IBD, IBE (temperature and precipitation), and IBB (Andes mountains) models, often proposed as individual drivers of genetic divergence, interact, and explain up to 33% of the genetic divergence in A. cephalotes. The IBE model remained significant after accounting for IBD, suggesting that environmental factors play a more prominent role than IBB. These factors, in combination with the idiosyncratic dispersal patterns of ants, appear to determine the hierarchical patterns of gene flow. This study enriches our understanding of the forces shaping population divergence in complex habitat landscapes.
A Jewish View of Contemporary Ideas of The Trinity
Authors: Brill Alan 
Published: October 2022

AbstractCan Jews get beyond treating the Trinity as tri‐theism? The essay reviews the relationship between Jewish theological notions of God and Christian understandings of the doctrine of the Trinity to move beyond the seeming impasse. Recent scholarship shows that Jews do not possess a pristine monotheism. Instead, Jewish theology often included complex views of God. In addition, currently Jews and Christians, especially at the highest levels of academic discourse, are in a “post‐polemical” era in which they read each other’s theological texts seriously for their own work and readily share and borrow from each other. The core of the article examines the Trinitarian thought of German Catholic theologians Karl Rahner and Jürgen Moltmann to evaluate similarities and differences between the two religions. The conclusion is that the Jewish concept of God and the Christian concept of the Trinity are not diametrically opposed in a zero‐sum way; nevertheless, actual differences between the religions should not be elided or minimized.
Efficacy of a lay community health worker (promotoras de salud) program to improve adherence to emollients in Spanish‐speaking Latin American pediatric patients in the United States with atopic dermatitis: A randomized, controlled, evaluator‐blinded study
Authors: Chen Henry W. , Limmer Emily E. , Joseph Adrienne K. , Kinser Kathryn , Trevino Amanda , Valencia Angel , Weinheimer Rachel A. , Youssef Sara Hassan , Cervantes Cecilia , Guzman Maria Teresa , Morales Ana , Morales Sandy , Contreras Maurica , Eifert Faye , LaMontagne Darci , Nouri Sarah , Reyes Fabiola , Pandya Amit G. , Dominguez Arturo R. 
Published: October 2022

AbstractBackgroundLatin American patients in the United States experience significant health disparities. Community health workers (promotoras de salud) reduce disparities by providing culturally appropriate education. While educational interventions have been studied in atopic dermatitis (AD), a chronic dermatologic condition affecting children, none have evaluated the use of promotoras in Spanish‐speaking pediatric patients in the United States.ObjectiveTo create and evaluate a promotora‐led education program for Spanish‐speaking caregivers of Latin American, pediatric patients with AD through a randomized, controlled, evaluator‐blinded study.MethodsChildren with moderate/severe AD (n = 48) were recruited from the pediatric dermatology clinic at Children's Health℠ in Dallas, TX and randomized to receive clinic education (n = 26) or clinic education plus promotora home visits (n = 22). The primary outcome was overall adherence to topical emollients over the 12‐week study, quantified by MEMSCap™ devices; several secondary endpoints were evaluated.ResultsIntention‐to‐treat analysis revealed a trend toward increased overall adherence to emollients over the 12‐week study period in promotora (median [interquartile range, IQR]: 43% [26%–61%]) versus non‐promotora (median [IQR]: 20% [11%–49%]) (p = .09) groups. SCORAD, AD knowledge, and Spanish‐language Parental Quality of Life Questionnaire for AD (Sp‐PIQoL‐AD) improved in both groups, although there was no statistically significant difference between groups. There was a trend toward increased AD knowledge at Week 4 (p = .06) in the promotora group.ConclusionsA promotora‐led educational intervention is a promising approach in increasing caregiver medication adherence in pediatric, Latin American patients with AD in the United States. Further research using creative and culturally appropriate strategies to increase medication adherence is necessary to reduce health disparities in other racial and ethnic minority populations in the United States.
When “the runs” also burns: Case reports of severe diaper dermatitis in children with acute gastroenteritis mimicking scald burns
Authors: Fanny Sanemba Aya , Burge Lauren , Small Amanda , Turbeville Jackson , Donaruma‐Kwoh Marcella , Adekunle‐Ojo Aderonke 
Published: October 2022

AbstractBurns to the buttocks of a child are highly concerning for child abuse unless there is a clear history to support an alternative diagnosis. We report two cases of severe erosive diaper dermatitis presenting as buttocks and perineal burns caused by prolonged exposure to diarrheal stool. These cases underscore the importance of making the right diagnosis to avoid the undue psychosocial stress to families that comes with a mistaken diagnosis of inflicted injury, and further add to our understanding of diarrheal contact burns in the absence of laxative use.
Prorocentrum pervagatum sp. nov. (Prorocentrales, Dinophyceae): A new, small, planktonic species with a global distribution
Authors: Tillmann Urban , Wietkamp Stephan , Gottschling Marc , Hoppenrath Mona 
Published: October 2022

SUMMARYProrocentrum comprises a unique group of dinophytes with several apomorphic traits, such as an apical insertion of flagella and the presence of two major, large thecal plates. Species delimitation is challenging, especially for morphologically very similar, small planktonic species. Contemporary analyses, including SEM studies and molecular phylogenetics of type material, are not available for many described species. Based on six strains isolated from Antarctic, subarctic and North Atlantic waters, Prorocentrum pervagatum sp. nov. is described. Prorocentrum pervagatum was small (12–16 μm long and deep), oval to round in outline, and moderately compressed. One small, pyrenoid‐like structure was faintly visible in some cells. Rod‐like, long trichocysts were present. Cells had one distinct apical spine (1.1–1.7 μm in length) visible in light microscopy. The plate surface appeared smooth in light microscopy with few pores located close to the plate margin visible in empty thecae. Electron microscopy revealed plates to be densely covered by small projections and two size classes of thecal pores. Cells had a row of mostly four large pores in apical‐ventral position on the right thecal plate. The periflagellar area consisted of eight small platelets. The apical spine was formed by platelet six. In molecular phylogenetics, P. pervagatum was part of a species group generally exhibiting small size and spiny thecal ornamentation, together with Prorocentrum cordatum and Prorocentrum obtusidens. The new species is distinct in DNA trees and differs from the protologues of other small species of Prorocentrum by the unique combination of size, shape (i.e. only moderately compressed or round), presence of a distinct apical spine, and position of thecal pores (i.e. located at the plate margins only). Its clear description and illustration may stimulate similar work of other small species of Prorocentrum, particularly including the re‐investigation of taxa with historical names collected at the corresponding type localities.
Naturally occurring anti‐PP1PK in a Chinese individual with p phenotype: A case based on compound heterozygosity including one novel allele
Authors: Liang Shuang , Wu Fan , Deng Zhi‐Hui , Liang Yan‐Lian , Peng Long , Su Yu‐Qing 
Published: October 2022

AbstractBackgroundThe null phenotype in P1PK blood group, known as “p,” is extremely rare in the whole world. Individuals of p phenotype spontaneously form anti‐PP1PK isoantibody. Here, we report a case of p phenotype with naturally occurring anti‐PP1PK isoantibodies in a Chinese individual.Study Design and MethodsSerology tests, containing alloantibodies screening and identification, were conducted to demonstrate the phenotype in P1PK blood group. The genotype of A4GALT gene was identified by haplotypes separation and sequencing.ResultsThe serological assay demonstrated the p phenotype of the proband, presenting with 1:64 titer of anti‐PP1PK. The sequencing data revealed a compound heterozygote consisting of A4GALT*P1.01 with c.343A>T and a novel allele based on A4GALT*01N.05 with an addition polymorphism c.100G>A. The sequence of the novel allele has been submitted to GenBank and the accession number OM912503 was assigned.ConclusionOur study demonstrates a case of naturally occurring anti‐PP1Pk in a Chinese individual with p phenotype, which is based on compound heterozygosity including one novel allele. As the proband is a young lady, monitoring the titer of anti‐PP1PK and early initiation of medical intervention are essential after her pregnancy.