bluuebunny/crossref_metadata_2025_split huggingface dataset:
CYCLIZATION IN OLEKSA STEFANOVYCH’S POETRY
Authors: Riazantseva Tetiana 
Published: February 2022

The article analyses the peculiarities of cyclization in Oleksa Stefanovych’s (1899—1970) poetry. Based on the theoretical definitions of a lyrical cycle (cycle of poems, sequence of poems) formulated in the works of Rolf Fieguth, Mikhail Darvin, Larisa Liapina, Ronald Vroon, Leonid Yanitskii, et al., the research outlines the main compositional, stylistic, thematic, and functional traits of Stefanovych’s lyrical cycles and demonstrates the evolution of certain key images in them. The material for analysis is taken from the collection of Stefanovych’s poetry published posthumously in Toronto (“Zibrani Tvory” / “Collected Works”, 1975).
The special attention is paid to his apocalyptic cycle “Kintsesvitnie” (“The World’s End”) that demonstrates the whole complex of architectonic and stylistic features inherent to a cycle of poems, particularly the presence of the ‘cyclic subject’ defined by R. Fieguth as “the subject of all creative, especially compositional, acts which are the basis of this poetic cycle” [13, 19].
The composition of “Kintsesvitnie” is based on the combination of the chronological and the plot development principles allowing to encompass Stefanovych’s creative work as a whole. The poems from various periods are selected and arranged so that they form a clear cyclic structure with steady imagery and a distinct thematic echo between its beginning and its end. Their dating reflects the consistency of the poet’s catastrophic worldview declared by the cycle’s title. It also demonstrates the evolution of its key metaphors (an evil bird, a thunderstorm, a trumpet) that arise in Stefanovych’s early works as visual or acoustic images and gradually evolve into the apocalyptic symbols of “Kintsesvitnie”.
Error Analysis on Students’ Writing in Using Simple Present Tense in Descriptive Text
Authors: Mukarromah Maulidatul , Suryanto Bradhiansyah Tri 
Published: February 2022

The objectives of this study are to know the types of errors and the dominant error made by the students of the ten grade of SMA Istiqlal. The researcher used the descriptive qualitative method as the research methodology. The data was collected from the written test done by the researcher. Based on the analysis that has done by the researcher, the result of the study found that all of the students produce error by total error 92 errors which classified into omission 46 error (50%), 5 error in addition (5,43%), 33 errors in miss-formation (35,86%) and 8 error in miss-ordering (8,69%). Thus, the dominant error was happened in the omission error by total error 46 errors (50%). The source of the error that made by the students are from interlingal and intra-lingual. However most of the errors are from the inralingual source which total 84 errors and 8 errors from inter-lingual.
Functional Effects of ARV-1502 Analogs Against Bacterial Hsp70 and Implications for Antimicrobial Activity
Authors: Brakel Alexandra , Kolano Lisa , Kraus Carl N. , Otvos Laszlo , Hoffmann Ralf 
Published: February 2022

The antimicrobial peptide (AMP) ARV-1502 was designed based on naturally occurring short proline-rich AMPs, including pyrrhocoricin and drosocin. Identification of chaperone DnaK as a therapeutic target in Escherichia coli triggered intense research on the ligand-DnaK-interactions using fluorescence polarization and X-ray crystallography to reveal the binding motif and characterize the influence of the chaperone on protein refolding activity, especially in stress situations. In continuation of this research, 182 analogs of ARV-1502 were designed by substituting residues involved in antimicrobial activity against Gram-negative pathogens. The peptides synthesized on solid-phase were examined for their binding to E. coli and S. aureus DnaK providing 15 analogs with improved binding characteristics for at least one DnaK. These 15 analogs were distinguished from the original sequence by their increased hydrophobicity parameters. Additionally, the influence of the entire DnaK chaperone system, including co-chaperones DnaJ and GrpE on refolding and ATPase activity, was investigated. The increasingly hydrophobic peptides showed a stronger inhibitory effect on the refolding activity of E. coli chaperones, reducing protein refolding by up to 64%. However, these more hydrophobic peptides had only a minor effect on the ATPase activity. The most dramatic changes on the ATPase activity involved peptides with aspartate substitutions. Interestingly, these peptides resulted in a 59% reduction of the ATPase activity in the E. coli chaperone system whereas they stimulated the ATPase activity in the S. aureus system up to 220%. Of particular note is the improvement of the antimicrobial activity against S. aureus from originally &gt;128 µg/mL to as low as 16 µg/mL. Only a single analog exhibited improved activity over the original value of 8 µg/mL against E. coli. Overall, the various moderate-throughput screenings established here allowed identifying (un)favored substitutions on 1) DnaK binding, 2) the ATPase activity of DnaK, 3) the refolding activity of DnaK alone or together with co-chaperones, and 4) the antimicrobial activity against both E. coli and S. aureus.
Impact of Systemic Inflammatory Response Syndrome on Clinical, Echocardiographic, and Computed Tomographic Outcomes Among Patients Undergoing Transcatheter Aortic Valve Implantation
Authors: Ahmed Tarek A. N. , Ki You-Jeong , Choi You-Jung , El-Naggar Heba M. , Kang Jeehoon , Han Jung-Kyu , Yang Han-Mo , Park Kyung Woo , Kang Hyun-Jae , Koo Bon-Kwon , Kim Hyo-Soo 
Published: February 2022

BackgroundSystemic inflammatory response syndrome (SIRS) is a systemic insult that has been described with many interventional cardiac procedures. The outcomes of patients undergoing transcatheter aortic valve implantation (TAVI) are thought to be influenced by this syndrome not only on short-term, but also on long-term.ObjectiveWe assessed the association of SIRS to different clinical, echocardiographic, and computed tomographic (CT) outcomes after TAVI.MethodsTwo hundred and twenty-four consecutive patients undergoing TAVI were enrolled in this study. They were assessed for the occurrence of SIRS within the first 48 h after TAVI. Patients were followed-up for short- and long-term clinical outcomes. Serial echocardiographic follow-ups were conducted at 1-week, 6-months, and 1-year. CT follow-up at 1 year was recorded.ResultsEighty patients (36%) developed SIRS. Among different parameters, only pre-TAVI total leucocytic count (TLC), pre-TAVI heart rate, and post-TAVI systolic blood pressure independently predicted the occurrence of SIRS. The incidence of HALT was not significantly different between both groups, albeit higher among SIRS patients (p = 0.1) at 1-year CT follow-up. Both groups had similar patterns of LV recovery on serial echocardiography. Long-term follow-up showed that all-cause death, cardiac death, and re-admission for heart failure (HF) or acute coronary syndrome (ACS) were significantly more frequent among SIRS patients. Early safety and clinical efficacy outcomes were more frequently encountered in the SIRS group, while device-related events and time-related valve safety were comparable.ConclusionAlthough SIRS implies an early acute inflammatory status post-TAVI, yet its clinical sequelae seem to extend to long-term clinical outcomes.
Neoantigen Quantity and Quality in Relation to Pancreatic Cancer Survival
Authors: Levink Iris J. M. , Brosens Lodewijk A. A. , Rensen Sander S. , Aberle Merel R. , Olde Damink Steven S. W. , Cahen Djuna L. , Buschow Sonja I. , Fuhler Gwenny M. , Peppelenbosch Maikel P. , Bruno Marco J. 
Published: February 2022

IntroductionFactors underlying antitumor immunity in pancreatic cancer (PC) are poorly understood. We hypothesized that not neoantigen quantity, but quality, is related to immune cell infiltration and survival.MethodologyWe performed genomic and transcriptomic profiling of paired normal, tumor tissue of 13 patients with PC with distinct survival times. Additionally, neoantigens prediction and immunological profiling were performed.ResultsThe proportion of neoantigens with a low similarity-to-self score was higher in short-term survivors (p &lt; 0.0001), while mutational load and burden, similarity-to-known-pathogens, and immunogenicity of neoantigens were not associated with immune cell infiltration or survival.DiscussionNo tumor mutational load or neoantigen quantity, but low similarity-to-self score, was associated with immune cell infiltration and survival.
Self-Consciousness of Appearance in Chinese Patients With Cleft Lip: Validation of the Chinese Derriford Appearance Scale 59 (DAS 59) Instrument
Authors: Sakran Karim A. , Song Sixing , Li Huo , Pan Peiyue , Chen Nan , Zeng Ni , Chi Ting , Shi Bing , Huang Hanyao , Wang Yan , Gong Caixia 
Published: February 2022

ObjectiveTo develop a reliable and valid Chinese version of the Derriford Appearance Scale 59 (DAS 59) instrument for assessing the self-consciousness of appearance in Chinese patients with cleft lip.MethodsThe original DAS 59 instrument was translated into Mandarin, back-translated, and culturally adapted among the Chinese population, following the protocol of the original DAS 59. The validation of the Chinese DAS 59 instrument was estimated on 443 adult participants including 213 subjects with a history of cleft lip with/without palate (CL/P, study group) and 230 normal subjects without facial appearance concern (control group). The reliability was estimated by Cronbach's α coefficient and Guttman's split-half coefficient. Content validity was tested using the Spearman correlation coefficient, while discriminant validity was tested by the Mann–Whitney U test.ResultsThe overall internal consistency of Chinese DAS 59 was excellent; Cronbach's α was 0.951 (α = 0.965 and 0.959 in the study and control groups, respectively). Further, Guttman's split-half coefficient was excellent in the study group (0.935) and control group (0.901). The validity of content was good with an acceptable correlation between all the items and domains. The construct validity through the discrimination was good with a statistically significant difference in most domains between the two groups. Patients with CL/P had more concern about the general self-consciousness and social self-consciousness of appearance. They also showed a good self-concept score.ConclusionThe Chinese version of DAS 59 demonstrated acceptable reliability and good construct and discriminant validity. It can be used for the research and assessment of the psychological state and quality of life for Chinese patients with cleft lip as well as other appearance problems and concerns.
High Performance Dual Ballistic and Thermal Neutrons Shields From Kevlar Fibers Reinforced Epoxy/B4C Hybrid Composites
Authors: Derradji Mehdi , Mehelli Oussama , Belgacemi Raouf , Abdous Slimane 
Published: February 2022

Targeting the development of advanced lightweight thermal and ballistic neutrons shields, a new hybrid composite was developed, for the first time, from Kevlar fibers, epoxy and boron carbide (B4C) particles. Kevlar fibers, as one of the strongest polymeric fillers, possess a high proportion of low Z atoms highly suitable for moderating neutrons. Meanwhile, these fibers can provide an additional efficient protection against high velocity projectiles. The B4C particles were added in various amounts, mainly for their excellent absorption of thermal neutrons. The nuclear shielding tests were performed at NUR research reactor using an optimized experimental setup. The obtained results confirmed the high shielding efficiency of all the developed materials. Meanwhile, the best performance was recorded at B4C amount of 20 wt.% with a macroscopic cross-section (Σ) of with a 3.638 cm−1 equivalent to a mean free path (λ) of 0.191 cm. The obtained results were compared with the most performant available shields and the data confirmed that superiority of the developed materials.
Analisis Resiko Kecelakaan Kerja di CV. Jati Jepara Furniture dengan Metode HIRARC (Hazard Identification Risk Assessment and Risk Control)
Authors: Willy Afredo Lamhot 
Published: February 2022

Industri saat ini sedang mengalami persaingan yang ketat, oleh karena itu penting bagi manajemen untuk melakukan evaluasi terhadap performa perusahaan dan perencanaan tujuan di masa mendatang. CV Super Jati Jepara Furniture adalah usaha yang bergerak di bidang produksi mebel, yaitu pembuatan seperti pintu, lemari, kursi, dll. Pabrik mebel ini memiliki beberapa potensi bahaya dikarenakan masih manual. Untuk mengidentifikasi, mengurangi, mengendalikan atau menghilangkan resiko yan terkait dengan progam kesehatan dan keselamatan kerja (K3) adalah menggunakan HIRARC (Hazard Identification Risk Assesment and Risk Control) adaalah salah satu metode teknik identifikasi, analisis bahaya dan pengendalikan resiko yang digunakan untuk meninjau proses atau operasi pada sebuah sistem secara sistematis. Dengan menggunakan Hazard Identification Risk Assesment Control (HIRARC), diharapkan dapat dilakukan usaha pencegahan terjadinya kecelakaan kerja yang terjadi di perusahaan dan menghindari serta menanggulangi resiko tersebut dengan yang tepat. Dalam penelitian ini data yang dikumpulkan dengan melakukan wawancara untuk memperoleh tentang proses kerja dan hal yang berkaitan dengan proses kerja, kejadian kecelakaan dalam proses kerja, pengumpulan data juga dilakukan dengan dokumentasi untuk mempelajari dokumen-dokumen perusahaan, buku-buku, laporan-laporan penelitan sejenis yang berhubungan. Dalam tahap penilain riiko dilakukan dengan cara melakukan penyebaran kuesioner kepada pekerja. Pada perusahaan tingkat kecelakaan ditetapkan dalam tiga kategori. Untuk nilai 4 dan 5 dikategorikan sebagai nilai tertinggi dengan resiko yang dapat mengganggu pernafasan, pendengaran, untuk nilai 3 dan 2 dikategorikan sebagai level medium yang dapat mengakibatkan luka pada tangan dan kaki, untuk nilai dikategorikan sebagai level terendah yang dapat mengakibatkan iritasi kulit.
Ethiopathogenetic Mechanisms of Formation of Diverticulosis and Diverticular Disease
Authors: Воробей А.В. , Костюк С.А. , Полуян О.С. , Хаджи Исмаил И.А. 
Published: February 2022

Дивертикулы ободочной кишки - наиболее частое анатомическое изменение, диагностируемое при колоноскопии. Распространенность данного заболевания выше у пожилых пациентов старше 65 лет со сдвигом в сторону снижения возраста (40-45 лет). Несмотря на высокую распространенность заболевания (по разным данным, от 7 до 20%), патофизиологические механизмы его формирования до конца не изучены. Установлено, что в формировании дивертикулов участвует множество факторов, которые в настоящее время признаны факторами риска развития данного патологического процесса: генетическая предрасположенность, нарушение моторики кишечника, образ жизни (в том числе употребление алкоголя, курение, избыточная масса тела), пищевое поведение (употребление красного мяса, низкое потребление клетчатки и т. д.), нарушение состава микробиоты толстого кишечника, а также прием лекарственных препаратов (нестероидные противовоспалительные средства, аспирин и др.).
Colon diverticula are the most common anatomical changes diagnosed with colonoscopy. The prevalence of this disease is higher in elderly patients over 65 years old with a shift towards decrease of age (40-45 years). Despite the high prevalence of the disease (according to various sources, from 7 to 20%), the pathophysiological mechanisms of its formation are not fully understood. It was found that many factors are involved in the formation of diverticula that are currently recognized as risk factors of development of this pathological process: genetic predisposition, alteration of colonic motility, lifestyle conditions (including alcohol consumption, smoking, overweight), eating behavior (consumption of red meat, low fiber intake, etc.), alterations in colonic microbiota composition, as well as certain medications (non-steroidal anti-inflammatory drugs, aspirin, etc.).
Las victimas perfectas:
Authors: Gantus María Eugenia 
Published: February 2022

Los yazidíes son una minoría religiosa kurda que no fue islamizada, lo que la diferencia y distancia del resto de los kurdos. En este artículo trabajaremos las particularidades de la religión yazidí en relación a sus creencias y a su organización social. Prestaremos especial atención a aquellas cuestiones religiosas que fueron malentendidas por sus vecinos musulmanes y cristianos, lo que los volvió particularmente vulnerables a los ataques de Daesh a partir de 2014.
Entre las mismas se encuentra la malinterpretación de su figura principal, el Ángel Pavorreal (Malak Tawús) y su errónea identificación con el diablo de las tradiciones abrahámicas. Veremos cómo su sistema de castas con las prácticas endogámicas que lo acompañan, favoreció el aislamiento del grupo, lo que fue aprovechado por Daesh para avanzar sobre su tierra, sus bienes y sus mujeres y niños.
Le elezioni comunali in Toscana dal 1993 al 2004. Gli effetti delle nuove regole, i partiti, le coalizioni, i "nuovi" sindaci
Authors: Floridia Antonio 
Published: February 2022

L’obiettivo di questo lavoro quello di fornire un bilancio critico e una valutazione degli effetti che l’applicazione della legge 81 del 25 marzo 1993 ha prodotto sui sistemi politici locali della Toscana: una legge che è stata più volte, e da più parti, definita come il frutto migliore della convulsa fase di crisi e di transizione che hanno vissuto le istituzioni politiche del nostro paese nel corso degli anni Novanta, – «un esempio di ingegneria istituzionale sostanzialmente andato a buon fine», come è stato detto –, ma di cui oggi, a distanza di anni, e dopo tre cicli elettorali, si possono cominciare a cogliere meglio le complesse implicazioni, individuando i processi di mutamento che le nuove regole hanno indotto, o con i quali esse si sono intrecciate, nel comportamento degli elettori e nelle strategie degli attori politici.
Ad oltre dodici anni dall’approvazione di questa legge, tutti i Comuni hanno già sperimentato per almeno tre volte il nuovo sistema elettorale. È possibile quindi disporre oggi di una mole rilevante di dati che permettono di valutare le modalità di funzionamento del nuovo sistema elettorale. Concentrare poi l’attenzione su una sola regione, la Toscana nel nostro caso, corrisponde ad un esigenza conoscitiva di particolare rilievo, proprio perché, come rilevava Giacomo Sani nella Prefazione ad uno degli studi più completi sull’argomento, apparso dopo la tornata elettorale del 1999, ciò che emerge sono appunto «le forti differenze a base regionale» che hanno caratterizzato l’impatto della nuova legge elettorale.
In questa ricerca, dunque, siamo partiti dalle specificità del sistema politico toscano, cominciando ad analizzare alcuni aspetti del voto amministrativo nel corso degli anni Ottanta e cercando di misurare, per quanto possibile, i mutamenti che il nuovo sistema elettorale ha prodotto. I comuni considerati dalla ricerca sono quelli che, sulla base dei dati del Censimento 1991, e poi di quello del 2001, hanno superato i 15 mila abitanti e per i quali, dunque, la nuova legge prevede un sistema elettorale a doppio turno: per la Toscana, si tratta di 51 comuni. Per questi comuni è stato predisposto un data base completo, oggi anche consultabile via internet, comprendente tutti i dati relativi alla partecipazione elettorale, i voti riportati dai candidati e dalle liste collegate, i seggi attribuiti a ciascuna lista. Generalmente, i dati sono stati analizzati anche sulla base delle diverse classi demografiche dei comuni e della diversa ampiezza dei consigli comunali5, e sulla base dei diversi cicli elettorali, in modo da consentire confronti omogenei
Evaluation of the Effectiveness of Using the Post-Isometric Relaxation (PIR) Technique and Exercises on the Mechanotherapy Apparatus in the Postoperative Period in Patients with Damage to the Rotator Cuff of the Shoulder
Authors: Roi I.V. , Borzykh N.O. , Cherniavskyi O.A. , Kravchuk L.D. , Rusanov A.P. , Katiukova L.D. , Yachnik S.P. 
Published: February 2022

Objective: to evaluate the effectiveness of performing exercises on an innovative mechanotherapy apparatus and the PIR technique for the recovery of patients with damage to the rotator cuff of the shoulder at the postoperative stage.
Materials and Methods. The study involved 46 patients after arthroscopic intervention due to damage to the structures of the shoulder joint. The reasons for arthroscopic intervention were: adhesive capsulitis (3 patients), damage to the rotator cuff of the shoulder (39 patients), and impingement syndrome (4 patients). The average age of patients was 44.7±8.3 years. All patients were divided into 2 groups: the control group (CG, n=21) and the main group (MG, n=25). The beginning of rehabilitation among patients averaged 4.9±2.4 weeks after the surgery. The duration of treatment was 4.5±3.2 weeks. The study was carried out on the basis of the Department of Rehabilitation of the SI “Institute of Traumatology and Orthopedics of NAMS of Ukraine” during 2020-2021.
Results and Discussion. According to the VAS results, the pain level after the rehabilitation program significantly decreased in both groups (p<0.05). In the MG, the dynamics of pain syndrome according to the VAS ranged from 6.2±1.2 cm to 0.9±0.7 cm 6 weeks after the surgery. In the CG, the majority of patients also noted an improvement in the level of pain after surgery (from 6.5±1.1 cm to 1.1±1.2 cm); no significant differences after treatment in terms of the level of pain between the patients in the MG and the CG (p>0.05) were observed. Also, patients who were included in the main group and did exercises with a simulator and elements of PIR according to the rehabilitation program showed generally better indicators of recovery of the function of the shoulder joint, namely there was a higher dynamics in increasing the amplitude of movements in the shoulder joint (112.5±10.60 flexion before physical rehabilitation (PR), 173.2±5.50 after РR). In the CG, the positive dynamics was less pronounced (107.7±6.80 flexion before PR, 151.2±6.50 after PR). Similar results were found according to the data of manual muscle testing (MMT).
Conclusions. Therefore, the method of post-isometric muscle relaxation using the proposed technique of training on a mechanotherapy apparatus for developing the shoulder joint is an effective method for treating postoperative contractures and can be recommended for the use in the complex rehabilitation of patients with contracture of the shoulder joint as a result of arthroscopic intervention in patients with injury of the rotator cuff of the shoulder.
PyExoRaMa: An Interactive Tool in Python to Investigate the Radius–Mass Diagram for Exoplanets
Authors: Francesco Amadori , Mario Damasso , Li Zeng , Alessandro Sozzetti 
Published: February 2022

Abstract
We present the python version of the software originally developed with Mathematica by Zeng et al. The code represents a useful tool for visualizing and manipulating data related to extrasolar planets and their host stars in a multi-dimensional parameter space. Its versatility enables statistical studies based on the large and constantly increasing number of detected exoplanets. It can be used to identify possible interdependence among several physical parameters, and to compare observables with theoretical models describing the exoplanet composition and structure. Our transposition to python presents some new features with respect to the original version, and due to the popularity of this programming language in the astrophysics community, the tool is made accessible to a larger number of users interested in exoplanet studies.