bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structuring Nanofibers of SMEC Sheets: A New Approach to Control Self‐Folded Shape by Uniaxial Stretching
Authors: Rabaux Oscar , Riva Raphaël , Noels Ludovic , Jérôme Christine 
Published: July 2022

AbstractShape‐memory elastomer composite (SMEC) sheets, made of a honeycomb structured electrospun poly(ε‐caprolactone) (PCL) fiber mat embedded in a silicone (PDMS) elastomer, fold on themselves upon uniaxial traction. The self‐folding of the composite sheet originates from a bi‐layered structure obtained by a simple one‐step impregnation process. Indeed, the impregnation of a structured PCL fiber mat by oily PDMS in a flat Teflon mold leads, after curing, to an asymmetric composite sheet made of one PDMS flat thin layer on the mold side and one rough PDMS/PCL composite layer on the other side due to specific affinities between the three polymers involved. The self‐folded shape of such structured single sheet obtained upon uniaxial stretching and stress release is controlled by the honeycomb pattern orientation versus stretching direction, by the pattern size and by the applied uniaxial stretching stress. High shape recovery and robust shape memory cycling are also demonstrated by dynamic mechanical analysis. This innovative process based on the mat structuration allows a straightforward one‐step fabrication of shape memory sheets, with a wide scope of tunable self‐folded curvatures exhibiting efficient temperature shape recovery.
Clinical Profile and Treatment Outcomes of Hypermanganesemia with Dystonia 1 and 2 among 27 Indian Children
Authors: Garg Divyani , Yoganathan Sangeetha , Shamim Uzma , Mankad Kshitij , Gulati Parveen , Bonifati Vincenzo , Botre Abhijeet , Kalane Umesh , Saini Arushi Gahlot , Sankhyan Naveen , Srivastava Kavita , Gowda Vykuntaraju K. , Juneja Monica , Kamate Mahesh , Padmanabha Hansashree , Panigrahi Debasis , Pachapure Shaila , Udani Vrajesh , Kumar Atin , Pandey Sanjay , Thomas Maya , Danda Sumita , Iqbalahmed Shaikh Atif , Subramanian Annadurai , Pemde Harish , Singh Varinder , Faruq Mohammed , Sharma Suvasini 
Published: July 2022

ABSTRACTBackgroundHypermanganesemia with dystonia 1 and 2 (HMNDYT1 and 2) are rare, inherited disorders of manganese transport.ObjectivesWe aimed to describe clinical, laboratory features, and outcomes among children with HMNDYT.MethodsWe conducted a retrospective multicenter study involving tertiary centers across India. We enrolled children between 1 month to 18 years of age with genetically confirmed/clinically probable HMNDYT. Clinical, laboratory profile, genetic testing, treatment details, and outcomes scored by treating physicians on a Likert scale were recorded.ResultsWe enrolled 27 children (19 girls). Fourteen harbored SLC30A10 mutations; nine had SLC39A14 mutations. The SLC39A14 cohort had lower median age at onset (1.3 [interquartile range (IQR), 0.7–5.5] years) versus SLC30A10 cohort (2.0 [IQR, 1.5–5.1] years). The most frequent neurological features were dystonia (100%; n = 27), gait abnormality (77.7%; n = 21), falls (66.7%; n = 18), and parkinsonism (59.3%; n = 16). Median serum manganese (Mn) levels among SLC39A14 (44.9 [IQR, 27.3–147.7] mcg/L) cohort were higher than SLC30A10 (29.4 [17.1–42.0] mcg/L); median hemoglobin was higher in SLC30A10 (16.3 [IQR, 15.2–17.5] g/dL) versus SLC39A14 cohort (12.5 [8.8–13.2] g/dL). Hepatic involvement and polycythaemia were observed exclusively in SLC30A10 variants. A total of 26/27 children underwent chelation with disodium calcium edetate. Nine demonstrated some improvement, three stabilized, two had marked improvement, and one had normalization. Children with SLC39A14 mutations had poorer response. Two children died and nine were lost to follow‐up.ConclusionsWe found female predominance. Children with SLC39A14 mutations presented at younger age and responded less favorably to chelation compared to SLC30A10 mutations. There is emerging need to better define management strategies, especially in low resource settings.
Preoperative dysphagia risk in community‐dwelling adults aged ≥50 years: Prevalence and risk factors
Authors: Canick Julia , Campbell James C. , Cohen Seth M. , Jones Harrison N. , Leiman David A. , Raman Sudha , Porter Starr Kathryn N. 
Published: July 2022

AbstractBackgroundPreoperative dysphagia screening is rare. The purpose of this study was to assess the prevalence and potential risk factors of preoperative dysphagia risk in adults preparing for surgery.MethodsThe Eating Assessment Tool (EAT‐10), Patient‐Generated Subjective Global Assessment Short Form (PG‐SGA SF), and Sarcopenia Screening Tool (SARC‐F) were self‐administered in adults preparing for surgery to identify dysphagia, malnutrition, and sarcopenia risk, respectively. Other variables collected include clinical demographics, fall risk, and surgical history associated with increased dysphagia risk. Descriptive summary statistics, univariate analysis, and logistic regression were performed as appropriate.ResultsThe median age was 69 years and preoperative dysphagia risk was 9.6%. Among 357 patients completing both EAT‐10 and PG‐SGA SF or SARC‐F, 7.3% had preoperative dysphagia and malnutrition risk and 7.2% had preoperative dysphagia and sarcopenia risk. Preoperative dysphagia risk was 2.7 times greater in those with prior surgical history associated with increased risk of dysphagia, 2.2 times higher in women, and almost twice as high in Black patients and patients with fall risk. Logistic regression revealed significant odds ratios (ORs) for prior surgical history associated with increased risk of dysphagia (OR, 2.95; 95% CI, 1.62–5.40) and male sex (OR, 0.52; 95% CI, 0.29–0.94), and a significant relationship between preoperative dysphagia and malnutrition risk (OR, 4.56; 95% CI, 2.02–10.28) when controlling for clinical variables.ConclusionThe high prevalence of dysphagia risk alone and in combination with malnutrition and sarcopenia risk in community‐dwelling adults underscores the need for standardized preoperative screening and optimization prior to surgery.
Non‐intrusive reduced‐order modeling using convolutional autoencoders
Authors: Halder Rakesh , Fidkowski Krzysztof J. , Maki Kevin J. 
Published: July 2022

AbstractThe use of reduced‐order models (ROMs) in physics‐based modeling and simulation almost always involves the use of linear reduced basis (RB) methods such as the proper orthogonal decomposition (POD). For some nonlinear problems, linear RB methods perform poorly, failing to provide an efficient subspace for the solution space. The use of nonlinear manifolds for ROMs has gained traction in recent years, showing increased performance for certain nonlinear problems over linear methods. Deep learning has been popular to this end through the use of autoencoders for providing a nonlinear trial manifold for the solution space. In this work, we present a non‐intrusive ROM framework for steady‐state parameterized partial differential equations that uses convolutional autoencoders to provide a nonlinear solution manifold and is augmented by Gaussian process regression (GPR) to approximate the expansion coefficients of the reduced model. When applied to a numerical example involving the steady incompressible Navier–Stokes equations solving a lid‐driven cavity problem, it is shown that the proposed ROM offers greater performance in prediction of full‐order states when compared to a popular method employing POD and GPR over a number of ROM dimensions.
Mass spectrometry and synchrotron‐FTIR microspectroscopy reveal the anti‐inflammatory activity of Bua Bok extracts
Authors: Paemanee Atchara , Rattanabunyong Siriluk , Ketngamkum Yanisa , Siriwaseree Jeeraprapa , Pongpamorn Ponkanok , Romyanon Kanokwan , Tangphatsornruang Sithichoke , Kuaprasert Buabarn , Choowongkomon Kiattawee 
Published: July 2022

AbstractIntroductionBua Bok or Centella asiatica (CA) is an Asian vegetable with anti‐inflammatory benefits. Asiaticoside, asiatic acid, madecassoside and madecassic have been characterised as major active ingredients with a wide range of pharmacological advantages. In manufacturing processes, high‐performance liquid chromatography (HPLC) and liquid chromatography–mass spectrometry (LCMS) are used to routinely determine the active compounds in raw materials.ObjectivesThis research aims to explore anti‐inflammatory properties, characterise metabolites and observe the biochemical changes of the inflammatory induced macrophages after pretreatment with the potential extracted fractions.MethodsBua Bok leaf extracts were prepared. Macrophages were pretreated with non‐toxic fractions to determine the anti‐inflammatory action. Tentative metabolites of effective fractions were identified by LC–MS. Synchrotron fourier‐transform infrared (S‐FTIR) microspectroscopy was utilised to observe the biochemical change of the lipopolysaccharide (LPS)‐induced cells after pretreatment with potential fractions.ResultsFractions of ethyl acetate, 30% and 100% ethanol highly increased the nitrile scavenging and suppressed the function of phospholipase A2. Fractions of 70% and 100% ethanol strongly decreased nitric oxide production. The comparison of 39 chemical compounds was presented. The change of proteins was improved after pretreatment of macrophages with fraction 70% ethanol. Fraction of 100% ethanol revealed the lipid accumulation was lower than 70% ethanol and diclofenac.ConclusionWhile the anti‐inflammatory actions of 70% and 100% ethanol were similar. S‐FTIR expressed they inhibited inflammatory response with the distinct features of biomolecules. The S‐FTIR, LC–MS and biological assay confidently provided the efficient strategies to inform the advantage of herbal extract on cellular organisation instead of a single compound.
New insights into the Van Krevelen diagram: Automated molecular formula determination from HRMS for a large chemical profiling of lichen extracts
Authors: Ollivier Simon , Jéhan Philippe , Olivier‐Jimenez Damien , Lambert Fabian , Boustie Joël , Lohézic‐Le Dévéhat Françoise , Le Yondre Nicolas 
Published: July 2022

AbstractIntroductionIn recent years, LC‐MS has become the golden standard for metabolomic studies. Indeed, LC is relatively easy to couple with the soft electrospray ionization. As a consequence, many tools have been developed for the structural annotation of tandem mass spectra. However, it is sometimes difficult to do data‐dependent acquisition (DDA), especially when developing new methods that stray from the classical LC‐MS workflow.ObjectiveAn old tool from petroleomics that has recently gained popularity in metabolomics, the Van Krevelen diagram, is adapted for an overview of the molecular diversity profile in lichens through high‐resolution mass spectrometry (HRMS).MethodsA new method is benchmarked against the state‐of‐the‐art classification tool ClassyFire using a database containing most known lichen metabolites (n ≈ 2,000). Four lichens known for their contrasted chemical composition were selected, and extractions with apolar, aprotic polar, and protic polar solvents were performed to cover a wide range of polarities. Extracts were analyzed with direct infusion electrospray ionization mass spectrometry (DI‐ESI‐MS) and atmospheric solids analysis probe mass spectrometry (ASAP‐MS) techniques to be compared with the chemical composition described in the literature.ResultsThe most common lichen metabolites were efficiently classified, with more than 90% of the molecules in some classes being matched with ClassyFire. Results from this method are consistent with the various extraction protocols in the present case study.ConclusionThis approach is a rapid and efficient tool to gain structural insight regarding lichen metabolites analyzed by HRMS without relying on DDA by LC‐MS/MS analysis. It may notably be of use during the development phase of novel MS‐based metabolomic approaches.
The impact of testicular cancer and its treatment on masculinity: A systematic review
Authors: Dax Victoria , Ftanou Maria , Tran Ben , Lewin Jeremy , Wallace Rebecca , Seidler Zac , Wiley Joshua F. 
Published: July 2022

AbstractObjectiveThe purpose of this review was to synthesise the literature on the topic of masculinity and testicular cancer (TC) and investigate the relative impact of TC on men's view of their masculinity.MethodsSearches were conducted across four databases (MEDline, PsycInfo, CINAHL Plus and Scopus) for articles published before April 2022 that included (1) TC and (2) masculinity. Two researchers independently rated studies for inclusion with a third resolving conflicts. Of the 6464 articles screened, 24 articles (10 quantitative and 14 qualitative) were included in the review. Articles were rated for quality and a narrative synthesis was performed.ResultsOverall, results indicated some men experience a shift in the way they relate to their sense of masculinity following diagnosis and treatment for TC. Being single and without children was related to the experience of negative masculinity‐related outcomes, possibly due to a compounding lack of relational support and being unable to conform to protector, provider traditions. Men who described testicle loss as symbolic of their diminished masculinity were also negatively impacted. However, recent, high‐quality literature on the topic using standardised masculinity measures was limited.ConclusionSome men experience a reduced sense of masculinity after TC, however the impact of TC on masculinity remains person dependent. Further research using validated masculinity measures is required to uncover psycho‐social variables that may account for whether and how meaning is made between TC and its treatment and any subsequent impact on perceived masculinity. Such factors may better support these men in life beyond cancer.Systematic review registration: PROSPERO.International Prospective Register of Systematic Reviews: CRD42020185649.
On‐orbit results for radial distances between collocated GEO satellites for RF analysis
Authors: Yilmaz Umit Cezmi 
Published: July 2022

SummaryBecause the GEO belt is becoming more and more crowded every day, controlling the number of satellites in the same control box is becoming more common. There are different kinds of collocation strategies to control more than two satellites in the same box, such as (1) eccentricity and inclination separation or (2) longitude separation. TURKSAT has been using option (1) for a long time. In this paper, we demonstrated TURKSAT on‐orbit experience to show mainly radial distances between the satellites. The motivation of this study is to demonstrate how often the satellites are becoming behind of each other, which can be used for RF colocation analysis. Most of the cases the worst case for RF interference analysis between two collocated satellites is having zero distance in normal and tangential but having a radial distance only. In this study, based on the radial distance thresholds, the noninterfered link availability is also shown.
Online communities on competing platforms: Evidence from game wikis
Authors: Loh Johannes , Kretschmer Tobias 
Published: July 2022

AbstractResearch SummaryMany platforms rely on volunteer contributions for value creation. Thus, unpaid contributors are valuable to the platform, but control over their activities is limited. We study whether and how volunteer communities can provide a competitive advantage and ask how contributor behavior depends on a platform's competitive position. We propose two channels: First, a stronger competitive position facilitates contributor coordination, leading to a larger active community. Second, a platform's competitive position is related to contributor motivation, which drives how much individuals contribute. Studying two competing game wiki platforms, we find that a platform's stronger competitive position is associated with higher activity, primarily driven by the number of contributors, which in turn triggers increased contributions by existing contributors. Further, high‐productivity contributors are especially active on a stronger platform.Managerial SummaryOnline “crowdsourcing” communities create value for many digital platforms, but managing them in a way that ensures productive contributions is challenging. To better understand the conditions under which online communities create value productively we analyze how contribution patterns differ between more and less successful platforms. We study 13 game wiki communities on two competing platforms and find that success is tied to higher activity, which is in turn the result of more manpower in the value creation process, but also higher productivity by individual contributors. In addition, a dedicated core of highly productive community members is an important driver of platform success. These findings have implications for the motivation of community members, and the entry and growth strategies of crowdsourced platforms.
Ferromagnetic‐Based Charge‐Accumulation Triboelectric Nanogenerator With Ultrahigh Surface Charge Density
Authors: Qi Youchao , Liu Guoxu , Bu Tianzhao , Zeng Jianhua , Zhang Zhi , Zhang Chi 
Published: July 2022

AbstractAn encouraging micro‐energy harvesting technology, the triboelectric nanogenerator (TENG), has been proven to transfer ambient environmental micro‐energy into electricity, but a low surface charge density results in low performance and limits the practical application of TENG. Here, a ferromagnetic‐based charge‐accumulation TENG (FC–TENG) is proposed with ultrahigh surface charge density and performances. The FC–TENG introduces a ferromagnetic media to enhance the output charge by magnetization effect. Meanwhile, the charge can also be continuously accumulated by the charge pump effects. Based on these two effects, an ultra‐high surface charge density of 2.85 mC m−2 is obtained under ambient atmospheric conditions using an ultra‐thin PET film (3 µm) and deposited Permalloy ferromagnetic electrodes. Meanwhile, the surface charge density of the FC–TENG can always maintain more than 1.5 mC m−2, even if the relative humidity arrives at 90%. This work provides a prospective technical mode to enhance the surface charge density of TENG, which would shed a new insight and guidance on the high‐performance TENG for various environmental conditions such as the ocean, industrial manufacturing, aerospace, and rail traffic.
A Single‐Atom Fe‐N‐C Catalyst with Ultrahigh Utilization of Active Sites for Efficient Oxygen Reduction
Authors: Ao Xiang , Ding Yong , Nam Gyutae , Soule Luke , Jing Panpan , Zhao Bote , Hwang Jee Youn , Jang Ji‐Hoon , Wang Chundong , Liu Meilin 
Published: July 2022

AbstractFe‐N‐C single‐atom catalysts (SACs) are emerging as a promising class of electrocatalysts for the oxygen reduction reaction (ORR) to replace Pt‐based catalysts. However, due to the limited loading of Fe for SACs and the inaccessibility of internal active sites, only a small portion of the sites near the external surface are able to contribute to the ORR activity. Here, this work reports a metal–organic framework‐derived Fe‐N‐C SAC with a hierarchically porous and concave nanoarchitecture prepared through a facile but effective strategy, which exhibits superior electrocatalytic ORR activity with a half‐wave potential of 0.926 V (vs RHE) in alkaline media and 0.8 V (vs RHE) in acidic media while maintaining excellent stability. The superior ORR activity of the as‐designed catalyst stems from the unique architecture, where the hierarchically porous architecture contains micropores as Fe SAC anchoring sites, meso‐/macro‐pores as accessible channels, and concave shell for increasing external surface area. The unique architecture has dramatically enhanced the utilization of previously blocked internal active sites, as confirmed by a high turnover frequency of 3.37 s−1 and operando X‐ray absorption spectroscopy analysis with a distinct shift of adsorption edge.
A change management roadmap for wasta‐free managerial practices in Arab organizations
Authors: Alsarhan Fadi 
Published: July 2022

AbstractWasta, which is the typical informal network style pervasive in the Arab world, has long been believed to constitute an intrinsic feature of managerial activities and practices in Arab organizations. With a long and intertwined history on one side, and a large widespread on the other, this practice seems near impossible to dissociate from the social and professional landscape of this part of the world. While more and more studies are emerging in order to understand the mechanisms of this practice, the conditions of its emergences, the factors which stand behind its widespread, and the consequences it brings forth, less attention has been directed towards proposing a solution for this problem. Some scholars have nonetheless attempted to offer practical indications on dealing with wasta in order to limit its spread and disintegrate its operational systems. This paper, which falls in line with these works, proposes a roadmap towards a wasta‐free management system in Arab organizations. Through formulating holistic and comprehensive measures in different levels and areas, this study hopes to contribute a clear roadmap, ready for use by global business leaders, managers, HR practitioners, and government executives alike.
Evolutionary fates of gene‐body methylation and its divergent association with gene expression in pigeonpea
Authors: Junaid Alim , Singh Nagendra Kumar , Gaikwad Kishor 
Published: July 2022

AbstractPigeonpea (Cajanus cajan L. Huth) is an agronomically important legume cultivated worldwide. In this study, we extensively analyzed gene‐body methylation (GbM) patterns in pigeonpea. We found a bimodal distribution of CG and CHG methylation patterns. GbM features‐ slow evolution rate and increased length remained conserved. Genes with moderate CG body methylation showed highest expression where as highly‐methylated genes showed lowest expression. Transposable element (TE)‐related genes were methylated in multiple contexts and hence classified as C‐methylated genes. A low expression among C‐methylated genes was associated with transposons insertion in gene‐body and upstream regulatory regions. The CG methylation patterns were found to be conserved in orthologs compared with non‐CG methylation. By comparing methylation patterns between differentially methylated regions (DMRs) of the three genotypes, we found that variably methylated marks are less likely to target evolutionary conserved sequences. Finally, our analysis showed enrichment of nitrogen‐related genes in GbM orthologs of legumes, which could be promising candidates for generating epialleles for crop improvement.
Transient respiratory arrest after quadratus lumborum block in a dog
Authors: Herrera‐Linares Manuel E. , Martínez Miguel 
Published: July 2022

AbstractA 13.9 kg, 4‐year‐old, male cocker spaniel dog was scheduled for cystotomy. Premedication consisted of intravenous medetomidine (5 µg/kg), induction with propofol (1 mg/kg, intravenous) and anaesthesia maintenance with isoflurane in O2 100%. A medetomidine constant‐rate infusion (1 µg/kg/h) was administered throughout. A bilateral quadratus lumborum block with 3 ml of 0.5% bupivacaine (each side) was performed, and intermittent positive‐pressure ventilation was initiated. At the end of the surgery, medetomidine constant‐rate infusion and intermittent positive‐pressure ventilation ceased. The patient remained in apnoea and developed severe hypercapnia (end‐tidal carbon dioxide: 12 kPa). Thirty minutes after isoflurane discontinuation, respiratory muscles movement started. Three days before, the dog underwent a mini‐hemilaminectomy (similar anaesthetic protocol) without complications. Epidural/spinal migration from the right quadratus lumborum block was suspected, although the definitive cause of transient respiratory arrest after bilateral quadratus lumborum block could not be ascertained. We advise caution when performing quadratus lumborum if previous neighbouring spinal surgery was performed.