bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relapsed and refractory yolk sac tumor of the peritoneum (mesentery): A case report and literature review
Authors: Zhou Xue , Zhao Lanbo , Feng Xue , Pan Zhenni , Bin Yadi , Zhang Siyi , Li Min , Guo Miao , Hou Huilian , Li Qiling 
Published: August 2022

BackgroundExtragonadal yolk sac tumor (YST) of peritoneum is a rare malignancy.Case DescriptionA 37-year-old Chinese woman was admitted to hospital with a 3-month abdominal pain 4 years ago. Alpha-fetoprotein was 228,499.0 ng/mL. Computed tomography scan revealed a massive mass in the left lower abdomen. Exploratory laparotomy exposed a huge mesenteric mass. Then, mesenteric tumor resection, partial sigmoidectomy, and single-lumen fistula of sigmoid colon were performed. Postoperative pathologic diagnosis reported a stage IV mesenteric YST. After surgery, the patient received 6 courses of BEP (bleomycin, etoposide, and cisplatin) chemotherapy. Seven months later, the patient underwent stoma reversion of sigmoid colon and received another 2 courses of BEP chemotherapy. Three months after the last chemotherapy, liver metastases were diagnosed. She subsequently underwent 3 surgeries, radiotherapy for liver metastases, and multiple tiers of palliative chemotherapies, including TP (docetaxel and carboplatin), VIP (ifosfamide, cisplatin, and etoposide), TIP (paclitaxel, ifosfamide, and cisplatin), and so on. After the third surgery (left hepatic lesion resection and right iliac lymph node resection), she received 4 cyclic chemotherapies of BEP´ (boanmycin, etoposide, and cisplatin) without pulmonary toxic side effects.ConclusionPostoperative histopathology and immunohistochemistry are gold standards for the diagnosis of peritoneal YST. The standard first-line treatment is surgery plus BEP chemotherapy. Second-line therapy regimens and above, including VIP and TIP, improve the prognosis of recurrent germ cell tumors. This relapsed and refractory patient with peritoneal YST benefits from the secondary BEP´ chemotherapy.
Quality assessment of clinical practice guidelines on psychological distress of cancer patients using the AGREE II instrument
Authors: Hao Ran , Jin Haoyu , Zuo Jinfan , Zhao Rumeng , Hu Jie , Qi Yixin 
Published: August 2022

ObjectiveThis study aimed to assess the quality of the clinical practice guidelines on psychological distress among cancer patients and provide users with recommendations for coping with psychological distress.MethodsA systematic search of relevant clinical practice guidelines was undertaken to identify and select the clinical practice guidelines related to psychological distress among cancer patients. Literature databases were searched in PubMed, Web of Science, Excerpta Medica Database, the Cumulative Index to Nursing &amp; Allied Health Literature, China Biology Medicine, China National Knowledge Infrastructure, WanFang and Weipu Journal Database. The guideline databases include Yimaitong Guidelines Network, National Guideline Clearinghouse, National Institute for Health and Clinical Excellence, American Society of Clinical Oncology (ASCO), New Zealand Guidelines Group, Scottish Intercollegiate GuidelinesNetwork, American Psychological Association, Registered Nurses’ Association of Ontario and Cancer Care Ontario (CCO). Four independent reviewers assessed the eligible guidelines using the Appraisal of Guidelines for Research and Evaluation (AGREE II) instrument.ResultsSix clinical practice guidelines were included and assessed for critical evaluation. The median score for the scope and purpose domain was 71.5% (IQR 64%-77.25%), the stakeholder involvement domain was 65% (IQR 47.5%-74.5%), the rigour of the development domain was 61.5% (IQR 45.5%-85.25%), the clarity of the presentation domain was 91% (IQR 72.25%-94.5%), the applicability domain was 70% (IQR 33%-78.75%), and the editorial independence domain was 48.84% (IQR 61.75%-95%). Four guidelines (ASCO, 2014; Canadian Association of Psychosocial Oncology, 2015; NCCN, 2020, and CCO, 2016) were classified as “recommended,” and the remaining (European Palliative Care Research Collaborative and Chinese Psychosocial Oncology Society) were “recommended with modifications,” especially in the domains of Stakeholder involvement, rigour of development, and applicability. The inter-rater consistency of each domain showed moderate level (0.52–0.90) analyzing by intraclass correlation.ConclusionsThe clinical practice guidelines on psychological distress among cancer patients varied in quality, and there were discrepancies in terms of the recommendations and recommendation grades. These findings could contribute to improving the quality of clinical practice guidelines on psychological distress, and enable the development and implementation of evidence-based guidelines for cancer patients.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO, identifier CRD42020209204.
Skeletal muscle metastasis from extrahepatic cholangiocarcinoma: A case report and literature review
Authors: Qian Hongwei , Huang Zhikun , Sun Xuezheng , Ren Peitu 
Published: August 2022

BackgroundCholangiocarcinoma (CCA) is a type of malignant tumor that arises from the epithelium of the bile ducts. According to anatomical location, CCA can be classified as intrahepatic (ICC), perihilar (PCC), or extrahepatic (ECC). CCA can invade and metastasize to other tissues in various ways, but distal skeletal muscle metastasis (SMM) is extremely rare. There are several reports on SMM from ICC or PCC, but SMM from ECC has not yet been reported.Case presentationA 71-year-old woman was diagnosed with ECC, for which she underwent pancreatoduodenectomy and partial hepatectomy. Nine months after surgery, she was re-admitted to the hospital complaining of a rapidly growing mass on her right thigh with progressive lower extremity edema. Magnetic resonance imaging of the right thigh showed two masses with iso-signal intensity on T1-weighted images and hyper-intensity on T2-weighted images compared with the surrounding muscles. Pathological examination of the fine-needle biopsy specimen revealed that it was similar to the previously detected ECC, and the diagnosis was metastasis of ECC. The patient was treated with opioid analgesics and died of systemic failure three months later.ConclusionSMM should be considered during the follow-up period despite its low incidence, and perineural invasion may be an essential pathway of distant metastasis in CCA.
A case report of primary colonic paraganglioma with lymph node metastasis
Authors: Zhu Xinyi , Huang Zhen , Dong Lin , Zhao Hong , Lu Haizhen 
Published: August 2022

BackgroundParaganglioma is a kind of neuroendocrine tumor that originates from paraganglia outside the adrenal gland. Gastrointestinal tract paraganglioma is very rare and only four cases of paraganglioma originating in the colon have been reported.Case PresentationWe report a case of metastatic paraganglioma originating in the colon, in which the differential diagnosis was established by comprehensively considering clinical information, histology, immunohistochemistry, and findings of fluorescence in situ hybridization and next generation sequencing analyses. The patient has remained well for over 14 months after the treatment.ConclusionSince all paraganglioma have metastatic potential, we believe that radical surgical resection and regular follow-up are necessary. Genetic testing may be indicative of metastatic potential and prognosis. Because colonic paraganglioma is very rare, differential diagnosis is very important. Our report provides experience for the diagnosis and study of paraganglioma in rare sites.
Employee Mental Health During COVID-19 Adaptation: Observations of Occupational Safety and Health/Human Resource Professionals in Ireland
Authors: Chen Yanbing , Ingram Carolyn , Downey Vicky , Roe Mark , Drummond Anne , Sripaiboonkij Penpatra , Buckley Claire , Alvarez Elizabeth , Perrotta Carla , Buggy Conor 
Published: August 2022

Objectives: This study aims to understand mental health issues among Irish employees arising from COVID-19 adaptation from the perspective of Occupational Safety and Health (OSH) and/or Human Resource (HR) professionals.Methods: Fifteen focus groups including 60 OSH/HR professionals from various sectors were conducted covering four predetermined themes. The data were transcribed verbatim, with transcripts entered into Nvivo for thematic analysis incorporating intercoder reliability testing.Results: The mental health impacts among employees are identified from three stages: pre-adaptation, during adaptation, and post-adaptation. Most issues were reported during the second stage when working conditions dramatically changed to follow emerging COVID-19 policies. The identified mental health support from participating organizations included providing timely and reliable information, Employee Assistance Programme (EAP), informal communication channels, hybrid work schedules and reinforcement of control measures.Conclusion: This study explores the challenges facing employees during the different stages of COVID-19 adaptation and the associated mental health impacts. Gender’s influence on mental health consultations should be considered when planning for public health emergencies, and further research conducted in male dominated industries.
Matlab Program for Determining the Inertia Characteristics of Flat Surfaces with Monte Carlo Algorithms
Authors: BOTIȘ Marius , PLEȘCAN Costel 
Published: August 2022

This paper presents a Matlab program for calculating the inertia tensor for complex plane surfaces. The calculation of the moments of inertia for plane surfaces with classical methods involves decomposing the surfaces into primitive surfaces and applying Steiner's relations. The classical methods are based on the knowledge of the analytical determined moments of inertia for primitive surfaces. In the case of complex surfaces, numerical methods can be used which are based on discretizing the surface into triangles and determining the moments of inertia by applying Steiner's relations knowing the analytical moments of inertia for a triangle. Both methods are computationally intensive and are basically based on the analytical moments of inertia of an elementary surface. In the case of large and complex surfaces the Monte Carlo algorithm can be used, which is a probabilistic algorithm based on the generation of area elements within the surface for which the moments of inertia are determined and then summed over the entire area bounded by the surface. The paper presents the Matlab calculation program and application examples for the use of the probabilistic Monte Carlo algorithm.
KAJIAN MODEL KESENJANGAN KAJIAN MODEL KESENJANGAN EKONOMI WILAYAH DI KAWASAN AGLOMERASI MALANG RAYA
Authors: Widodo Widiyanto Hari Subagyo , Imaduddina Annisaa  Hamidah , Nurul Hidayati Agustina 
Published: August 2022

Kondisi dan potensi setiap wilayah sangat beragam dengan karakteristik masing- masing. Hal ini menjadikan tingkat tumbuh dan berkembangnya suatu wilayah menjadi berbeda- beda. Karena perbedaan kondisi wilayah sehingga tingkat tumbuh dan berkembangnya wilayah menjadi berbeda maka kondisi ini menyebabkan terjadinya ketidakmerataan kecepatan pengembangan dan pembangunan wilayah atau yang disebut disparitas/ kesenjangan. Kesenjangan akan menjadi masalah bila terjadi kesenjangan yang terlalu besar dan disebabkan oleh sistem pembangunan yang salah, sehingga dapat menjadi penyebab munculnya keresahan, ketidakpuasan dan bahkan sampai timbul aksi dari sekelompok masyarakat untuk memisahkan diri dari NKRI. Permasalahan mendasar pada pengembangan wilayah di Kawasan Metropolitan terutama Malang Raya adalah kesenjangan antara daerah dimana pembangunan di monosentris, terpusat pada Kota Malang. Menanggapi kondisi demikian, dibutuhkan perumusan model kesenjangan wilayah di Malang Raya, untuk mengetahui sejauh mana pemusatan pembangunan dan pertumbuhan wilayah di Malang Raya. Selain itu diharapkan melalui perumusan model kesenjangan wilayah mampu menjadi acuan sehingga arahan dapat meminimalkan kesenjangan wilayah di Malang Raya
UJI BANDING EFEKTIFITAS ROUGHING FILTER ALIRAN HORIZONTAL DAN ALIRAN UPFLOW DALAM REDUKSI KADAR KEKERUHAN DAN KESADAHAN AIR SUNGAI BRANTAS
Authors: Setyobudiarso Hery , Sudiro Sudiro , Agnes Agnes Tyagita 
Published: August 2022

Air merupakan kebutuhan dasar yang sangat penting dalam kehidupan sehari-hari. Karena keberadaannya yang sangat penting tersebut, maka berbagai usaha dilakukan untuk memperolehnya dengan memanfaatkan air dari berbagai sumber. Air sungai biasanya tidak dapat langsung digunakan, karena umumnya kotor dan tercemar. Oleh karena itu, perlu dilakukan pengolahan air untuk memenuhi syarat sebagai air minum/air bersih dengan pengolahan pendahuluan salah satunya dengan menggunakan proses filtrasi, yaitu dengan memakai alat Roughing Filter. Penelitian bertujuan untuk mengetahui kemampuan Roughing Filter aliran horizontal dan Roughing Filter aliran Up Flow terhadap penurunan konsentrasi kekeruhan dan kesadahan air sungai Brantas. Hasil penelitian menunjukkan bahwa Roughing filter aliran horizontal dan upflow dengan media batu kapur dan batu kerikil memiliki kemampuan dalam menurunkan kandungan kesadahan dan kekeruhan dari air sungai.Pada Roughing Filter Aliran Horizontal penurunan kekeruhan air sungai paling tinggi diperoleh pada media cangkang kerang dan batu apung dengan waktu 210 menit dengan persentase penurunan kandungan kekeruhan sebesar 90,92% dan kesadahan sebesar 51.59%. Pada Roughing Filter Aliran Upflow penurunan kekeruhan paling tinggi diperoleh pada diameter media 19 mm – 22 mm dengan perbandingan ketinggian media batu kapur 100 cm: batu kerikil 0 cm, pada waktu 60 menit dengan nilai persentase 28,7036 % (26 NTU). penurunan konsentrasi kesadahan paling tinggi diperoleh pada diameter media 19 mm – 22 mm, perbandingan ketinggian media batu kapur 25 cm : batu kerikil 75 cm, pada waktu 60 menit dengan nilai persentase 49,0585 % (79,37 mg/l)
Desain Game Karakter 3d Tokoh Madura dengan Actionscript Macromedia
Authors: Ashari Mohammad Ibrahim , Faisol Ahmad 
Published: August 2022

Desain karakter sangat penting dalam menciptakan rasa ketertarikan akan jalan cerita yang ada dalam sebuah game. Flash game yaitu game 2D yang dibuat dengan menggunakan software Macromedia Flash pada umumnya menampilkan desain karakter 2D yang tidak dibuat dengan software pengolah grafik 3D. Sehingga desain karakter yang digunakan umumnya tampak flat karena tidak memiliki efek-efek seperti pada desain karakter game 3D. Game action “ putra sakera ” adalah game action 2D yang dibuat dengan menggunakan software Macromedia Flash dan menggunakan desain karakter 3D yang dibuat dengan software pengolah grafik tiga dimensi 3Ds Max 7. Desain karakter tiga dimensi ( 3D ) yang terdapat di dalam game “ putra sakera “ dan dibuat dengan aplikasi pendukung 3Ds Max 7 dapat berjalan dengan baik ketika dikompilasi ke dalam Macromedia Flash berupa animasi gerakan karakter dalam bentuk png sequence dengan teknik frame by frame animation. Dengan menggunakan desain karakter 3D yang unik akan menjadi daya tarik tersendiri dalam game flash” putra sakera ” ini sehingga membedakan dengan game-game flash pada umumnya yang hanya menampilkan desain karakter dua dimensi ( 2D ).
Aplikasi Penggunaan Iot pada Pengukuran Tangki Penyimpanan Solar Secara Real Time
Authors: Sulistiawati Irrine Budi , Firdaus Aji Akbar , Nahdliyah Sisca Dina Nur , Yunardi Riky Tri , Setiawan Yudha Bhakti 
Published: August 2022

Pengukuran tangki penyimpanan bahan bakar minyak (solar) merupakan hal yang penting dan harus dilakukan oleh beberapa perusahaan industri. Di beberapa perusahaan industri ada yang masih menggunakan pengukuran tangki penyimpanan bahan bakar secara manual atau pengukuran secara langsung, namun hasil yang diperoleh tidak akurat apalagi jika cuaca tidak mendukung sehingga menyebabkan kurangnya pencahayaan. Penelitian disini, melakukan monitoring tangki penyimpanan solar secara real time berbasis internet of things (IoT) menggunakan sensor SRF04 dan menggunakan pengontrol utama NodeMcu ESP8266, sehingga dapat dilakukan pengkuran level tangki dengan mudah karena tidak perlu lagi melakukan pengukuran secara manual menggunakan tongkat besi pengukur. Komunikasi data jarak jauh dan uji coba tingkat akurasi data menunjukkan bahwa sistem monitoring ini dapat memberikan data akurat dan real time. Alat ini bekerja dengan memancarkan transmitter sensor ultrasonik dan mengeluarkan gelombang ultrasonic, kemudian diterima kembali oleh receiver ultrasonik dan di proses pada nodemcu dan ditampilkan pada lcd dan aplikasi Blynk. Blynk juga dapat mengatur on/off pompa melalui relay yang terhubung pada nodemcu. Dari simulasi pengujian yang dilakukan diperoleh total persentase kesalahan sebesar 0.10 % dan total nilai error sebesar 0.12 ml.
Implementasi Artificial Neural Network pada Kendali Bola Pendulum
Authors: Arrival Hidayat Danu , Fauzan Farras , Dwi Cahyo Andy , Eka Yulian Dhany , Thaifur Muhammad , Pambudi Wahyu S 
Published: August 2022

AI (Articifial Intelegence) merupakan suatu system yang dimana memiliki kegunaan agar mempermudah pengerjaan dari suatu pekerjaan yang diharuskan menggunakan tenaga manusia yang dimana bisa digantikan dengan machine learning/ system AI dalam bidang industri seperti melakukan pemilihan barang, pemetaan tempat, pendeteksian suatu barang termasuk baik atau buruk, dan lain-lain. Artificial Neural Network merupakan salah satu dari system tersebut, pengunaannya bisa di gunakan dalam beberapa hal yaitu seperti memetakan pola dari input ke pola baru pada output, dan pendulum digunakan sebagai perantara input untuk melakukan pemetaan pola input ke pola baru yang menghasilkan output
Pemanfaatan Limbah (Ampas Tebu Kering, Kulit Pisang Kering, Kulit Nanas Kering) pada Pemurnian Minyak Jelantah
Authors: Setyawati Harimbi , Putra M. Satria Mandala , Azarine Evelyn Natasya 
Published: August 2022

Minyak jelantah dapat merusak kesehatan manusia, menimbulkan penyakit kanker, pengendapan lemak pada pembuluh darah dan dapat mengurangi kecerdasan, karena di dalam minyak jelantah terdapat senyawa-senyawa yang bersifat karsiogenik (Alamsyah et al., 2017). Oleh karena itu, perlu dilakukam proses pemurnian minyak goreng bekas sebelum dibuang ke lingkungan (Miskah et al., 2019). Kualitas minyak goreng ditentukan dari komponen asam lemak penyusunnya, yakni golongan asam lemak jenuh atau tidak jenuh. Asam lemak tidak jenuh mengandung ikatan rangkap. Sebaliknya, asam lemak jenuh tidak mempunyai ikatan rangkap. Asam lemak yang memiliki semakin banyak ikatan rangkap akan semakin reaktif terhadap oksigen sehingga cenderung mudah teroksidasi. Sementara itu, asam lemak yang rantainya dominan mengandung ikatan tunggal cenderung lebih mudah terhidrolisis. Kedua proses kerusakan tersebut dapat menurunkan kualitas minyak. Reaksi penting lain adalah hidrogenasi, yaitu penjenuhan ikatan rangkap oleh hidrogen. Pengaruh waktu rendam terhadap kemurnian minyak jelantah yang dihasilkan dari amoas tebu, kulit nanas, dan juga kulit pisang yaitu: waktu optimum pada pemurnian minyak jelantah adalah di waktu ke-72 jam, bahan penyerap yang sangat baik dgunakan adalah ampas tebu, kandunga lignin pada kulit pisang mengalami penurunan sebesar 0,88% untuk kulit nanas sebesar 0,35% dan untuk ampas tebu sebesar 1,27%.
Pengurusan Alam Pembelajaran di Sekolah Kebangsaan Nanga Temalat Sarawak
Authors: Amran Nur Fatin Najwa , Hashim Nurul Farzana , Jumadi Mohd Khairul Nizam , Mohamad Jamil Norzaimah , Ibrahim Noraini , Sagin Cyrilyn , Husin Mohd Razimi 
Published: August 2022

Guru merupakan individu yang memainkan peranan penting dalam pengurusan alam pembelajaran. Pengurusan alam pembelajaran perlu bagi merangsang minat belajar kanak-kanak. Pengurusan alam pembelajaran penting bagi memenuhi masa yang diperuntukkan untuk mengajar dan juga memastikan objektif pembelajaran dan pengajaran tercapai serta menarik perhatian pelajar terhadap sebuah pengajaran. Sekolah Kebangsaan Nanga Temalat di Sarawak menjadi pilihan untuk melaksanakan kajian tentang pengurusan alam pembelajaran yang mana seorang responden adalah seorang guru daripada Sekolah Kebangsaan Nanga Temalat. Pengurusan alam pembelajaran perlu dilakukan sebelum PDP, semasa PDP dan selepas PDP. Kajian ini mendapati bahawa pengurusan alam pembelajaran yang mantap dan efektif adalah merupakan kunci utama dalam keberhasilan suatu pengajaran dan pembelajaran. Guru perlu menitikberatkan aspek pengurusan alam pembelajaran supaya minat setiap murid dapat dipupuk dengan lebih berkesan di samping dapat memastikan guru dapat menyampaikan maklumat kepada murid-murid dengan lebih lancar sekaligus guru juga dapat meningkatkan pencapaian setiap murid.
Learning Environment Management at Nanga Temalat National School Sarawak
Abstract: Teachers are individuals who play an important role in the management of the learning environment. Management of the learning environment is necessary to stimulate children's interest in learning. The management of the learning environment is important to meet the time allotted for teaching and also to ensure that learning and teaching objectives are achieved and attract students' attention to a lesson. Nanga Temalat National School in Sarawak was chosen to carry out a study on the management of the learning environment where one respondent was a teacher from Nanga Temalat National School. Learning environment management needs to be done before PDP, during PDP and after PDP. This study found that the management of a robust and effective learning environment is the main key to the success of teaching and learning. Teachers need to focus on the management aspect of the learning environment so that each student's interest can be nurtured more effectively while also being able to ensure that the teacher can convey information to the students more smoothly and at the same time the teacher can also improve the achievement of each student.
Keywords: Learning, Learning Environment Management, SWOT.
A Review of Current-Limiting Control of Grid-Forming Inverters Under Symmetrical Disturbances
Authors: Fan Bo , Liu Teng , Zhao Fangzhou , Wu Heng , Wang Xiongfei 
Published: August 2022

<p>Grid-forming (GFM) inverters are recognized as a viable solution to increase the penetration of renewable energy in bulk power systems. However, they are physically different from synchronous generators in terms of overcurrent capability. To protect the power semiconductor devices and support the power grid under severe symmetrical disturbances, the GFM control systems should be able to achieve the following requirements: current magnitude limitation, fault current contribution, and fault recovery capability. Various current-limiting control methods are reported in the literature to fulfill these goals, including current limiters, virtual impedance, and voltage limiters. This paper presents an overview of those methods. Emerging challenges that need to be addressed, including temporary overcurrent, unspecified output current vector angle, undesired current saturation, and transient overvoltage, are pointed out. Comparative simulations are conducted to demonstrate the performance of different methods under grid voltage drops and phase jumps. Finally, open issues of current-limiting control methods for GFM inverters, including transient stability assessment, voltage source behavior under overcurrent conditions, and windup of voltage controllers, are shared. </p>