bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE EFFECTIVENESS OF USING 3D SIMULATION MEDIA IN ONLINE LEARNING OF MOLECULAR GEOMETRY ON IMPROVING LEARNING
Authors: Rohmah Nissa Ulfatu 
Published: August 2022

AbstractMolecular geometry is one of the materials in chemical bonds that are abstract. Where students must think imaginatively in predicting the three-dimensional shape of an existing molecule. But because it is abstract the majority of students have difficulty understanding and visualizing the theory of molecular form. This problem is coupled with online learning that makes it difficult for teachers to convey molecular geometry materials. The solution to the problem is the use of interactive learning media for PhET 3D simulation. This study aims to determine the effectiveness of the use of 3D simulation media in online learning of molecular geometry materials. This research is an experimental research in the form of pre- experimentation with the design of one group pretest posttest. Data collection techniques are carried out with tests and questionnaires. Sampling is done by purposive sampling. The result of N-Gain data analysis of experiment class 0.79 with percentage of N-Gain score of 79.8 % with high criteria. This shows that the use of 3D simulation media in online learning of molecular geometry molecular shapes is very effectively used in the teaching and learning process. Hypothesis testing is carried out t-paired with a level of trust of 5%. Interpretation of hypothesis testing by looking at the value of Sig (2 tailed) of 0.00 where 0.00 < 0.05. it can be concluded that there are significant differences in the use of 3D simulation media. Based on effect size test the value obtained is 0.98 with high criteria. These results can be interpreted that the use of 3D simulation media in molecular geometry learning has a scale of effect or strong influence on student learning outcomes. The result of student response data analysis there are four aspects, namely, aspects of students' interest in following learning, material understanding, ease of problem solving, and group cooperation. Aspects of students' interest in following learning and material understanding aspects have excellent criteria. As for the aspect of ease of problem solving and group cooperation has good criteria. Keyword: 3D simulation media, Online learning, Molecular Geometry, Learning outcomes
Analisis Kualitas Pelayanan Terhadap Pelayanan Jasa Reparasi Motor di PT Kemakmuran Jaya Mandiri
Authors: Panuntun Stefanus Katon Bagus , Al-Faritsy Ari Zaki 
Published: August 2022

PT Kemakmuran Jaya Mandiri ialah sebuah usaha yang bergerak di sektor penjualan kendaraan roda dua Honda turut melayani jasa reparasi motor honda. Banyaknya pelanggan yang kurang merasa puas dengan kinerja mekanik dan ruang tunggu yang diberikan oleh perusahaan. Dengan permasalahan yang ada perlu dilakukan analisa kepuasan konsumen agar perusahaan mengetahui atribut mana yang akan diperbaiki. Metode dalam penelitian ini yaitu observasi dan melakukan penyebaran kuisioner yang berisikan 15 pertanyaan sebanyak 40 responden. Penelitian ini menggunakan metode Importance Performance Analysis dan Lean Service. Importance Perfomance Analysis digunakan untuk mengetahui atribat manakah yang memiliki kepentingan tinggi. Lean Service untuk menghilangkan waste aktivitas yang tidak bernilai tambah. Hasil dari penelitian ini, berdasarkan pada diagram kartesius terdapat 3 atribut pelayanan yang memiliki tingkat kepentingan yang tinggi namun memiliki kinerja yang rendah. Atribut tersebut yaitu, dimensi daya tanggap, keahlian, dan empati. Oleh karena itu perlu dilakukan perbaikan untuk meningkatkan kualitas dengan membuat usulan berdasarkan metode Lean Service dan penggambungan antara proses pengecekan motor dengan proses konsumen mendaftar serta menghapus pengecekan akhir.Importance Performance, Kepuasan pelanggan Analysis, Lean Service
Social autopsy analysis of the determinants of neonatal and under-five mortalities in Nigeria, 2013-2018
Authors: Wammanda Robinson D , Quinley John , Eluwa George I , Odejimi Adeyinka , Kunnuji Michael , Weiss William , Jalingo Inuwa B , Ayokunle Olorunimbe T , Nte Alice R , King Rebekah , Franca-Koh Ana C 
Published: August 2022

Background Nigeria suffers from one of the world’s highest child mortality rates, with about 900,000 deaths in a single year, despite being classified as a middle-income country. Over the past few years, substantial efforts have been made to reduce child mortality, with under-five mortality declining by 31.6% between 1990 and 2018. However, this decline is slower than needed to reduce child mortality significantly. This study presents the social autopsy component of the 2019 verbal and social autopsy (VASA) survey to provide an in-depth understanding of the social determinants of under-five mortality in Nigeria. Methods The study was a cross-sectional inquiry into the social determinants of neonatal and 1-59 months child deaths from the 2018 Nigeria Demographic and Health Survey (NDHS) weighted to represent the Nigerian population. The social autopsy survey asked about maternal care for neonates and 1-59 months children during the final illness. Results Child mortality in Nigeria in children aged 1-59 months is strongly associated with levels of wealth, place of residence, and maternal education. The association of these same socio-economic factors with neonatal mortality is weaker. While there were significant associations with wealth quintiles and geopolitical zones, higher maternal education was not significantly associated with lower neonatal death rates. Maternal complications in pregnancy and/or labour and delivery were common and strongly associated with stillbirths and deaths in the first two days. Severity scores at the inception of the illnesses did not show differences between children who only received informal care versus those who went to formal care providers. The main barriers to care were distance, cost, transport, and the need to travel at night, and these barriers were interlinked. More distant facilities usually required vehicle transport, which was expensive for low-income families. Travelling for an emergency at night was even more difficult in terms of finding and paying for transport and involving problems with insecurity and bad roads. Conclusions The family, community, and health system factors related to neonatal and 1-59 months child deaths in Nigeria were highlighted in this study. Deaths were commonly associated with numerous factors, each of which could contribute to the sequence of events resulting in a preventable death.
Pengaruh Tingkat Pendidikan, Usia Ibu, Tingkat Penghasilan Keluarga terhadap Child Well Being pada Keluarga Ekonomi Lemah
Authors: Erhamwilda Erhamwilda , Afrianti Nurul , Dudi Asep , Husnu Alma 
Published: August 2022

Berbagai penelitian menunjukkan anak dari keluarga ekonomi lemah rawan mendapat kekerasan. Perlu dikembangkan program parenting bagi orang tua dari keluarga ekonomi lemah berbasis pada temuan child well being. Penelitian ini bertujuan untuk melihat pengaruh usia ibu, pekerjaan ibu, tingkat pendidikan ibu, serta penghasilan keluarga terhadap Well Being anak usia dini. Penelitian menggunakan pendekatan kuantitatif dengan metode deskriptif. Sampel dipilih secara purposive yaitu keluarga ekonomi menengah ke bawah di salah satu RW, yang banyak penduduk miskin dan ada kasus kekerasan anak. Responden penelitian 88 orang. Data dikumpulkan dengan instrument child well being yang teruji validitas reliabilitasnya. Hasil Analisis Regresi Linear berganda Dummy variabel menunjukkan variabel usia, pendidikan terakhir, dan penghasilan keluarga secara bersama – sama tidak berpengaruh terhadap Child Weil Being, ada variabel lain yang lebih berpengaruh terhadap well being anak usia dini dari keluarga ekonomi lemah. Temuan menunjukkan tidak selamanya kesejahteraan ekonomi menjadi variabel yang menentukan tingkat child well being
Video Pembelajaran Al-Islam Kemuhammadiyahan untuk Meningkatkan Keterampilan Berbicara dan Karakter Anak Usia Dini
Authors: Susanty Meida , Mahyuddin Nenny 
Published: August 2022

Keterampilan berbicara merupakan hal yang perlu dilatih pada usia dini agar anak mampu mengungkapkan pengetahuan, ide dan perasaaannya sehingga dapat diterima pada lingkungannya. Karakter adalah nilai-nilai positif yang dibentuk pengetahuan, perasaan dan perilaku moral yang ditumbuhkembangkan dalam kepribadian. Al Islam Kemuhammadiyahan (AIK) sebagai karakteristik dari lembaga pendidikan Muhammadiyah/Aisyiyah memerlukan media yang tepat untuk menyampaikan pembelajaran yang terintegrasi dengan kurikulum 2013 PAUD. Tujuan penelitian untuk mengembangkan video pembelajaran AIK yang valid, praktis dan efektif untuk meningkatkan keterampilan berbicara dan karakter anak usia dini di TK Aisyiyah. Jenis penelitian ialah penelitian dan pengembangan (RD) dengan model ADDIE. Hasil penelitian menunjukkan video pembelajaran AIK dapat meningkatkan keterampilan berbicara dan karakter anak sesuai hasil penilaian oleh ahli materi pada persentase 93%, ahli media 93% dan ahli bahasa 96% dengan kategori sangat valid. Selanjutnya hasil praktikalitas video AIK mendapatkan nilai rata-rata 94% dengan kategori sangat praktis dan hasil efektifitas pada nilai rata-rata 92% dengan kategori sangat efektif digunakan dalam pembelajaran anak usia dini
Pendidikan Anak Usia Dini dalam Perspektif Gender
Authors: Bastian Adolf , Novitasari Yesi 
Published: August 2022

Melaksanakan pendidikan berperspektif gender pada anak usia dini diperlukan perencanaan sebagai langkah awal untuk memberikan arah yang tepat dalam pelaksanaan proses pembelajaran di PAUD. Penelitian ini merupakan penelitian deskriptif dengan menggunakan pendekatan kuantitatif. Populasi penelitian ini mencakup TK se-kecamatan Marpoyan Damai. Adapun sampel penelitian ini berjumlah 30 guru TK yang diambil dengan teknik purposive sampling. Hasil penelitian ini menunjukkan bahwa penyusunan kurikulum berperspektif gender pada pendidikan anak usia dini dapat dipersentasekan 48, 83 % dengan kategori tidak baik, dan pelaksanaan kurikulum berperspektif gender pada pendidikan anak usia dini dapat dipersentasekan 60,17 % dengan kategori baik. Dengan kata lain meskipun dalam penyusunan kurikulum belum menunjukkan perspektif gender, namun dalam pelaksanaan pembelajaran di pendidikan anak usia dini sudah berjalan baik. Sehingga selanjutnya guru di PAUD Marpoyan Damai harus menyesuaikan antara kurikulum yang disusun, dengan kegiatan pembelajaran yang dilakukan.
Prevalence of Anxiety and Depression among College Students in Kathmandu, Nepal
Authors: Khadka Rakshya , Bista Suman , Bista Sujana , Sapkota Sajani , Baskota Swechhya 
Published: August 2022

Introduction: Anxiety and depression are among the most common mental health problems, and they are highly comorbid with each other. Many college students experience several mental health issues because of academic pressure, family expectations, difficult environment, and controlling people. Hence, the objective of the current study was to investigate the prevalence of anxiety and depression in college students of Kathmandu, Nepal, as very limited studies have been conducted in this area.
Methods: This was a cross-sectional study conducted in 504 students (317 male & 187 female, age range = 15 to 21 years, mean age = 17.12±0.90 years) of grade 11 and 12 studying in nine randomly selected colleges of Kathmandu valley, Nepal. Participants with chronic medical illness and severe mental disorders were excluded from the study. A semi-structured questionnaire was used to obtain the information related to socio-demography, and the Hospital Anxiety and Depression Scale (HADS) to assess the status of anxiety and depression in college students. Data were entered and analysed using Statistical Package for Social Sciences (SPSS) version 20.0. Results were presented in frequency and percentage.
Results: The prevalence of anxiety in college students was 53.97%. Where, 28.57% students had mild anxiety, 18.85% had moderate anxiety, and 6.55% had severe anxiety. Similarly, the prevalence of depression in college students was found to be 39.88%. Where, 22.42% students had mild depression, 13.69% had moderate depression, and 3.77% had severe depression.
Conclusion: The prevalence of both anxiety and depression among college students in Kathmandu valley, Nepal, was found to be very high. The Government of Nepal and other concerned bodies should pay attention to this area.
OPTIMALISASI PEMASARAN TANAMAN OLERIKULTURA (KASUS PADA PEMASARAN CABAI BESAR DI KOTA PAYAKUMBUH)
Authors: Reza Muhamad , Hamida Rosi 
Published: August 2022

Cabai besar merupakan salah satu komoditas olerikultura yang dihasilkan di Kota Payakumbuh. Fluktuasi harga cabai besar yang sering dihadapi petani, mengakibatkannya sulit memasarkan cabe dengan harga layak. Kondisi tersebut menimbulkan kerugian petani, pada saat harga berada dibawah biaya produksi yang dikeluarkan petani. Oleh karena itu, perlu dilakukan penelitian dengan tujuan mengoptimalkan pemasarannya melalui perumusan strategi pemasaran cabai besar yang dilaksanakan di Kota Payakumbuh. Penelitian ini dilakukan selama 3 bulan dengan metode kuantitatif. Jenis penelitian yang digunakan yaitu penelitian studi kasus. Jumlah responden penelitian sebanyak 30 orang yang terdiri dari petani cabai besar dan pelaku pemasaran cabai besar. Variabel utama terdiri dari lembaga pemasaran, saluran pemasaran, margin pemasaran, fungsi pemasaran, permsalahan pemasaran, dan strategi pemasaran. Data dikumpulkan dengan metode kuesioner, observasi dan dokumentasi. Teknik analisa data yang digunakan yaitu deskriptif kuantitatif. Temuan yang didapatkan yaitu lembaga pemasarannya terdiri dari pedagang perantara, pedagang pengumpul, dan sub terminal agribisnis. Saluran pemasaran yang ditemukan mulai dari saluran pemasaran pendek sampai dengan saluran pemasaran panjang. Margin pemasaran cabai sebesar Rp. 1.000,- sampai dengan Rp 2.000,- per kg. Permasalahan utama pemasaran cabai besar yaitu terjadinya fluktuasi harga yang tidak bisa dikendalikan petani dan pelaku pasar, belum tersedianya kebijakan pemerintah untuk mengatasi fluktuasi harga cabai besar dan tidak berjalannya fungsi terminal agribisnis sebagai inovasi yang dimiliki oleh pemerintah. Stragi yang dapat digunakan yaitu mengoptimalkan peran pemerintah, memperpendek saluran pemasaran dan membangun industri antara dan hilir berbahan baku cabe di Kota Payakumbuh.
Kata Kunci: fluktuasi, saluran pemasaran, fungsi pemsaran, strategi pemasaran.
Diagnostic Value of Metagenomic Next-Generation Sequencing for Pulmonary Infection in Intensive Care Unit and Non-Intensive Care Unit Patients
Authors: Zhou Jing-Jiang , Ding Wei-Chao , Liu Yan-Cun , Gao Yu-Lei , Xu Lei , Geng Run-Lu , Ye Ying , Chai Yan-Fen 
Published: August 2022

ObjectiveTo evaluate the diagnostic performance of metagenomic next-generation sequencing (mNGS) and culture in pathogen detection among intensive care unit (ICU) and non-ICU patients with suspected pulmonary infection.MethodsIn this prospective study, sputum samples were collected from patients with suspected pulmonary infection for 2 consecutive days and then subjected to DNA or RNA sequencing by mNGS or culture; 62 ICU patients and 60 non-ICU patients were admitted. In the end, comparisons were made on the pathogen species identified by mNGS and culture, the overall performance of these two methods in pathogen detection, and the most common pathogens detected by mNGS between the ICU and non-ICU groups.ResultsIn DNA and RNA sequencing, the positive rate of pathogen detection reached 96.69% (117/121) and 96.43% (108/112), respectively. In culture tests, the positive rate of the pathogen was 39.34% (48/122), much lower than that of DNA and RNA sequencing. In general, the positive rate of pathogen detection by sputum mNGS was significantly higher than that of sputum culture in the total and non-ICU groups (p &lt; 0.001) but did not show a significant difference when compared to the result of sputum culture in the ICU group (p = 0.08). Haemophilus spp., Candida albicans, Enterococcus spp., and viruses from the mNGS results were excluded before comparing the overall performance of these two methods in pathogen detection. Specifically, among the 10 most common bacteria implied from the mNGS results, significant differences were observed in the number of cases of Haemophilus parainfluenzae, Acinetobacter baumannii, Klebsiella pneumoniae, Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Staphylococcus aureus, and Enterococcus faecalis between the ICU and non-ICU groups (p &lt; 0.05).ConclusionsThis study demonstrated the superiority of mNGS over culture in detecting all kinds of pathogen species in sputum samples. These results indicate that mNGS may serve as a valuable tool to identify pathogens, especially for ICU patients who are more susceptible to mixed infections.
Prognostic implications of coronary artery disease and stress tests in patients with elevated left ventricular filling pressure and preserved ejection fraction
Authors: Seo Jeong Hun , Hong David , Youn Taeho , Lee Seung Hun , Choi Ki Hong , Kim Darae , Park Taek Kyu , Lee Joo Myung , Song Young Bin , Choi Jin-Oh , Hahn Joo-Yong , Choi Seung-Hyuk , Gwon Hyeon-Cheol , Jeon Eun-Seok , Yang Jeong Hoon 
Published: August 2022

BackgroundThe prognostic role of myocardial ischemia in patients with heart failure with preserved ejection fraction (HFpEF) has not been fully elucidated. Therefore, we investigated the change in echocardiographic parameters and clinical outcomes based on the presence of epicardial coronary artery disease (CAD) and positive stress tests in HFpEF patients.MethodsSymptomatic patients with left ventricular end diastolic pressure ≥15 mmHg who underwent coronary angiography were analyzed between January 2000 and August 2019 after exclusion of patients with acute coronary syndrome.ResultsA total of 555 HFpEF patients were invasively confirmed, 285 (51%) had angiographically-proven CAD. HFpEF patients with CAD displayed greater deterioration in left ventricular ejection fraction (p = 0.002) over time but this was not observed in those without CAD (p = 0.99) on follow-up echocardiography; however, the mitral annulus early diastolic velocity (e') was significantly decreased in both groups (p &lt; 0.001 and p = 0.003, respectively). Among 274 patients that received stress tests, those with positive stress tests showed a decline in e' (p 0.001), but this was not found in subjects with negative stress tests (p = 0.44). There was no significant difference in all-cause mortality between patients with CAD and without CAD (p = 0.26) with a median follow-up of 10.6 years.ConclusionIn HFpEF patients, CAD was associated with greater deterioration in the left ventricular systolic function but not with mortality during the follow-up. In addition, myocardial ischemia with a positive stress test may contribute to greater deterioration of diastolic dysfunction.
Intercomparison of Atmospheric Upper-Air Temperature From Recent Global Reanalysis Datasets
Authors: Essa Yassmin H. , Cagnazzo Chiara , Madonna Fabio , Cristofanelli Paolo , Yang Chunxue , Serva Federico , Caporaso Luca , Santoleri Rosalia 
Published: August 2022

Atmospheric temperature is a key variable to detect and attribute climate change. Due to the relative sparseness of ground-based observations and heterogeneity of satellite data, global atmospheric reanalysis products are considered valuable datasets for studying and monitoring the climate, since these usually ensure spatially complete and continuous temporal coverage. Consequently, evaluating differences among the existing reanalyses is key to identifying inconsistencies. To this aim, the current study intercompares the climatological mean, variability, and linear trends for upper air temperature provided from four recent atmospheric reanalysis products (ERA5, ERA-Interim, MERRA-2, and JRA-55) The Reanalysis Multi-Model Ensemble-mean (RMME) is used as a comparator. Radiosonde observations are included for comparison on the regional scale (tropics). The results reveal that all evaluated reanalyses provide a consistent reproduction of the upper-air temperature profile. Temperature differences from RMME within ±0.25 K are found in both the troposphere and lower stratosphere, except for a few specific regions. Larger differences (&gt;± 1.5 K) and discrepancies among the datasets are found in the upper stratosphere. Agreement between reanalyses increased after 1998. Differences in the temperature time series and seasonal cycle at the regional scales are smaller in the Northern Hemisphere mid-latitudes than in the tropics and Southern Hemisphere. A robust cooling trend in the lower stratosphere during the period of largest ozone depletion (1980-1997) and a warming trend in the troposphere for the period 1998-2018 are clearly found, at the global level, in all the datasets. Temperature trends and variability in the tropics are consistent in all reanalysis datasets with the homogenized radiosonde records from the lower to middle troposphere and in the lower stratosphere. However, large differences are found in the upper troposphere, tropical tropopause layer (TTL), and middle stratosphere. The well-known temperature variability in the lower stratosphere associated with Quasi-Biennial Oscillation (QBO) is captured in both reanalyses and observational datasets. Among the reanalyses, ERA5 shows the smallest temperature difference with respect to homogenized upper-air radiosoundings records.
LncRNA DUXAP8 as a prognostic biomarker for various cancers: A meta-analysis and bioinformatics analysis
Authors: Wang Yongfeng , Jiang Xianglai , Zhang Dongzhi , Zhao Yuanbin , Han Xiaoyong , Zhu Lihui , Ren Jingyao , Liu Yubin , You Jiarong , Wang Haolan , Cai Hui 
Published: August 2022

Background: Dual homeoboxes A pseudogene 8 (DUXAP8) is a newly discovered long noncoding RNA that has been shown to function as an oncogene in a variety of human malignant cancers. By integrating available data, this meta-analysis sought to determine the relationship between clinical prognosis and DUXAP8 expression levels in diverse malignancies.Materials and methods: A systematic search was performed to identify eligible studies from several electronic databases from their inception to 25 October 2021. Pooled odds ratios and hazard ratios with 95% CI were used to estimate the association between DUXAP8 expression and survival. For survival analysis, the Kaplan-Meier method and COX analysis were used. Furthermore, we utilized Spearman’s correlation analysis to explore the correlation between DUXAP8 and tumor mutational burden (TMB), microsatellite instability (MSI), the related genes of mismatch repair (MMR), DNA methyltransferases (DNMTs), and immune checkpoint biomarkers.Results: Our findings indicated that overexpression of DUXAP8 was related to poor overall survival (OS) (HR = 1.63, 95% CI, 1.49–1.77, p &lt; 0.001). In addition, elevated DUXAP8 expression was closely related to poor OS in several cancers in the TCGA database. Moreover, DUXAP8 expression has been associated with TMB, MSI, and MMR in a variety of malignancies.Conclusion: This study revealed that DUXAP8 might serve as a prognostic biomarker and potential therapeutic target for cancer. It can be used to improve cancer diagnosis, discover potential treatment targets, and improve prognosis.