bluuebunny/crossref_metadata_2025_split huggingface dataset:
Presumed congenital nictitating membrane dysplasia in a Japanese white rabbit
Authors: Masatsugu Miki , Atsumi Ikuyo , Yamagiwa Yoshinori , Haranosono Yu , Kurata Masaaki 
Published: May 2022

AbstractObjectiveThe present report characterises a spontaneous nictitating membrane abnormality in a Japanese white rabbit.Animal studiedThe animal was a male Japanese white rabbit (Oryctolagus cuniculus, Kbs:JW, 10 weeks old at the time of purchase) that had not received any treatment. A morphological abnormality of the nictitating membrane in the animal's right eye was detected.ProceduresOphthalmological examinations, including slit‐lamp biomicroscopy, corneal and conjunctival staining with fluorescein and lissamine green, fundoscopy, blinking rate measurement, Schirmer's tear test, and tonometry were performed. The animal was euthanised at 15 weeks of age, and histopathological examinations of the abnormal nictitating membrane, palpebral conjunctiva, eyelid and eyeball were performed.ResultsThe tip of the nictitating membrane adhered to the palpebral conjunctiva of the medial canthus. The eye and periocular tissues showed no abnormalities in the ophthalmological examinations, except for the structure of the nictitating membrane. Histopathological examination revealed that the adhered site of the nictitating membrane and the palpebral conjunctiva consisted of dense fibrous connective tissue that was consecutive to the conjunctiva adjacent to the eyelid margin and lamina propria of the nictitating membrane. The fibrous connective tissue was covered with stratified squamous epithelium.ConclusionBased on these results, we diagnosed this abnormal finding as congenital nictitating membrane dysplasia. This paper is the first case report describing a congenital structural abnormality of the nictitating membrane in a Japanese white rabbit.
Variable‐rate infusion of adrenaline to manage hypotension in an anaesthetised goat
Authors: Casoria Vincenzo , Auckburally Adam , Rocchi Attilio 
Published: May 2022

AbstractTreatment of hypotension in domestic ruminants is more challenging than in other species, due to strict drug legislation and a limited number of licensed drugs in food‐producing animals. The use of adrenaline as a variable‐rate infusion to improve haemodynamics is a viable treatment option when other interventions fail. Further studies are needed to establish appropriate infusion rates and potential side effects in goats.
Whooping and sandhill cranes visit upland ponds proportional to migration phenology on the Texas coast
Authors: Butler Matthew J. , Metzger Kristine L. , Sanspree Colt R. , Cain James W. , Harris Grant M. 
Published: May 2022

AbstractTwo crane species, whooping cranes (Grus americana) and sandhill cranes (Antigone canadensis), overwinter along the Texas Gulf Coast. Periodic, extreme drought conditions have prompted concerns that potential freshwater limitations could hinder conservation of cranes, especially endangered whooping cranes. In response, land managers constructed and maintained freshwater ponds in upland areas near saltmarshes on the wintering grounds. We monitored 30 of those constructed ponds using camera traps (1 Oct 2013–31 May 2014) to quantify crane visits. For each species, we modeled pond visits as a function of migration phenology and environmental variables at 2 scales. Pond‐scale variables included distance to saltmarsh and monthly salinity, and broad‐scale variables included bay salinity, drought index, and tide level. We found pond visits by both crane species followed migration phenology with the greatest pond use in January–February. Both crane species visited ponds more on the mainland than on Matagorda Island. Sandhill crane visits were fewer at ponds with higher salinities and those filled by well water. Cranes visited ponds during the diurnal period and tended to avoid visiting ponds during the first 10% of the day. Pond visits by whooping cranes were ≤0.15 times/pond/day and by sandhill cranes were ≤0.28 times/pond/day. Our results suggested crane visits to constructed ponds may not be as frequent as once assumed nor driven by tidal and salinity conditions in the bay. The greater number of crane visits to constructed ponds on the mainland compared to Matagorda Island may be related to shrub encroachment around natural freshwater swale wetlands on the mainland, which is not as prevalent of a problem on the island. With proper management, swales on the mainland may provide alternatives to constructed ponds for cranes to obtain freshwater and forage.
Speed Discrimination in the Apparent Haptic Motion Illusion
Authors: Lacôte I. , Gueorguiev D. , Pacchierotti C. , Babel M. , Marchal M. 
Published: May 2022

AbstractWhen talking about the Apparent Haptic Motion (AHM) illusion, temporal parameters are the most discussed for providing the smoothest illusion. Nonetheless, it is rare to see studies addressing the impact of changing these parameters for conveying information about thevelocityof the elicited motion sensation. In our study, we investigate the discrimination of velocity changes in AHM and the robustness of this perception, considering two stimulating sensations and two directions of motion. Results show that participants were better at discriminating the velocity of the illusory motion when comparing stimulations with higher differences in the actuators activation delay. Results also show limitations for the integration of this approach in everyday life applications.
Fuzzy Dark Matter candidates from string theory
Authors: Cicoli Michele , Guidetti Veronica , Righi Nicole , Westphal Alexander 
Published: May 2022

Abstract
String theory has been claimed to give rise to natural fuzzy dark matter candidates in the form of ultralight axions. In this paper we revisit this claim by a detailed study of how moduli stabilisation affects the masses and decay constants of different axion fields which arise in type IIB flux compactifications. We find that obtaining a considerable contribution to the observed dark matter abundance without tuning the axion initial misalignment angle is not a generic feature of 4D string models since it requires a mild violation of the Sf ≲ MP bound, where S is the instanton action and f the axion decay constant. Our analysis singles out C4-axions, C2-axions and thraxions as the best candidates to realise fuzzy dark matter in string theory. For all these ultralight axions we provide predictions which can be confronted with present and forthcoming observations.
Probing light mediators and (g − 2)μ through detection of coherent elastic neutrino nucleus scattering at COHERENT
Authors: Corona M. Atzori , Cadeddu M. , Cargioli N. , Dordei F. , Giunti C. , Li Y. F. , Picciau E. , Ternes C. A. , Zhang Y. Y. 
Published: May 2022

Abstract
We present the constraints on the parameters of several light boson mediator models obtained from the analysis of the current data of the COHERENT CEνNS experiment. We consider a variety of vector boson mediator models: the so-called universal, the B − L and other anomaly-free U(1)′ gauge models with direct couplings of the new vector boson with neutrinos and quarks, and the anomaly-free Le− Lμ, Le− Lτ, and Lμ− Lτ gauge models where the coupling of the new vector boson with the quarks is generated by kinetic mixing with the photon at the one-loop level. We consider also a model with a new light scalar boson mediator that is assumed, for simplicity, to have universal coupling with quarks and leptons. Since the COHERENT CEνNS data are well-fitted with the cross section predicted by the Standard Model, the analysis of the data yields constraints for the mass and coupling of the new boson mediator that depend on the charges of quarks and neutrinos in each model under consideration. We compare these constraints with the limits obtained in other experiments and with the values that can explain the muon g − 2 anomaly in the models where the muon couples to the new boson mediator.
Optimal configuration of Protvino to ORCA experiment for hierarchy and non-standard interactions
Authors: Singha Dinesh Kumar , Ghosh Monojit , Majhi Rudra , Mohanta Rukmani 
Published: May 2022

Abstract
In this paper, we study the hierarchy sensitivity of Protvino to ORCA (P2O) experiment in three flavour scenario as well as its sensitivity to non-standard interactions (NSI) in neutrino propagation. Because of the largest possible baseline length of 2595 km, P2O is expected to have strong sensitivity towards neutrino mass hierarchy and NSI parameters. In our study, we show that even though the number of appearance channel events for the minimal configuration of P2O are higher compared to DUNE, still the hierarchy sensitivity of P2O is less than DUNE because of large background events. Our results show that for a background reduction factor of 0.46 and appearance channel background systematic normalization error of 4%, the hierarchy sensitivity of P2O becomes equivalent of DUNE for δCP = 195°. We call this configuration of P2O as optimized P2O. Regarding the study of NSI, we find that, for ϵeμ (ϵeτ) sensitivity of DUNE is similar (better) as compared to optimized P2O when both ϵeμ and ϵeτ are included in the analysis. Our results show that in presence of NSI, the change of hierarchy sensitivity with respect to standard three flavor scenario, is higher in P2O as compared to DUNE. Further, hierarchy sensitivity in presence of NSI is lower (higher) than sensitivity in the standard three flavour scenario for δCP = 270°(90°). It is important to note that hierarchy sensitivity of optimized P2O does not get significantly better than DUNE for the current favourable values of δCP which is 180° < δCP< 360° as obtained by the global analysis in both standard three flavour and in presence of NSI.
Wilson coefficients and natural zeros from the on-shell viewpoint
Authors: Rose Luigi Delle , von Harling Benedict , Pomarol Alex 
Published: May 2022

Abstract
We show how to simplify the calculation of the finite contributions from heavy particles to EFT Wilson coefficients by using on-shell methods. We apply the technique to the one-loop calculation of g − 2 and Hγγ, showing how finite contributions can be obtained from the product of tree-level amplitudes. In certain cases, due to a parity symmetry of these amplitudes, the total contribution adds up to zero, as previously found in the literature. Our method allows to search for new natural zeros, as well as to obtain non-zero contributions in a straightforward way.
Reheating and dark matter freeze-in in the Higgs-R2 inflation model
Authors: Aoki Shuntaro , Lee Hyun Min , Menkara Adriana G. , Yamashita Kimiko 
Published: May 2022

Abstract
We study the post-inflationary dynamics for reheating and freeze-in dark matter in the Higgs-R2 inflation model. Taking the perturbative approach for reheating, we determine the evolution of the temperature for radiation bath produced during reheating and determine the maximum and reheating temperatures of the Universe. Adopting a singlet scalar dark matter with a conformal non-minimal coupling and a vanishing Higgs-portal coupling, we discuss the freeze-in production of dark matter both from the non-thermal scattering during reheating and the thermal scattering after reheating. We find that thermal scattering is dominant for dark matter production in our model due to the high reheating temperature. The reheating temperature in our model is determined dominantly by the Higgs condensate to be up to about 1014 GeV and dark matter with masses up to about 109 GeV can be produced with a correct relic density.
Shifted quiver quantum toroidal algebra and subcrystal representations
Authors: Noshita Go , Watanabe Akimi 
Published: May 2022

Abstract
Recently, new classes of infinite-dimensional algebras, quiver Yangian (QY) and shifted QY, were introduced, and they act on BPS states for non-compact toric Calabi-Yau threefolds. In particular, shifted QY acts on general subcrystals of the original BPS crystal. A trigonometric deformation called quiver quantum toroidal algebra (QQTA) was also proposed and shown to act on the same BPS crystal. Unlike QY, QQTA has a formal Hopf superalgebra structure which is useful in deriving representations.In this paper, we define the shifted QQTA and study a class of their representations. We define 1d and 2d subcrystals of the original 3d crystal by removing a few arrows from the original quiver diagram and show how the shifted QQTA acts on them. We construct the 2d crystal representations from the 1d crystal representations by utilizing a generalized coproduct acting on different shifted QQTAs. We provide a detailed derivation of subcrystal representations of ℂ3, ℂ3/ℤn(n ≥ 2), conifold, suspended pinch point, and ℂ3/(ℤ2× ℤ2).
Wheat glutamine synthetase TaGSr-4B is a candidate gene for a QTL of thousand grain weight on chromosome 4B
Authors: Yang Fan , Zhang Jingjuan , Zhao Yun , Liu Qier , Islam Shahidul , Yang Wuyun , Ma Wujun 
Published: May 2022

Abstract
Key message
Glutamine synthetase TaGSr-4B is a candidate gene for a QTL of thousand grain weight on 4B, and the gene marker is ready for wheat breeding.

Abstract
A QTL for thousand grain weight (TGW) in wheat was previously mapped on chromosome 4B in a DH population of Westonia × Kauz. For identifying the candidate genes of the QTL, wheat 90 K SNP array was used to saturate the existing linkage map, and four field trials plus one glasshouse experiment over five locations were conducted to refine the QTL. Three nitrogen levels were applied to two of those field trials, resulting in a TGW phenotype data set from nine environments. A robust TGW QTL cluster including 773 genes was detected in six environments with the highest LOD value of 13.4. Based on differentiate gene expression within the QTL cluster in an RNAseq data of Westonia and Kauz during grain filling, a glutamine synthesis gene (GS: TaGSr-4B) was selected as a potential candidate gene for the QTL. A SNP on the promoter region between Westonia and Kauz was used to develop a cleaved amplified polymorphic marker for TaGSr-4B gene mapping and QTL reanalysing. As results, TGW QTL appeared in seven environments, and in four out of seven environments, the TGW QTL were localized on the TaGSr-4B locus and showed significant contributions to the phenotype. Based on the marker, two allele groups of Westonia and Kauz formed showed significant differences on TGW in eight environments. In agreement with the roles of GS genes on nitrogen and carbon remobilizations, TaGSr-4B is likely the candidate gene of the TGW QTL on 4B and the TaGSr-4B gene marker is ready for wheat breeding.
Relationships Between Muscle Parameters and History of Falls and Fractures in the Hertfordshire Cohort Study: Do All Muscle Components Relate Equally to Clinical Outcomes?
Authors: Laskou Faidra , Westbury Leo D. , Fuggle Nicholas R. , Edwards Mark H. , Cooper Cyrus , Dennison Elaine M. 
Published: May 2022

AbstractIn previous work, relationships between muscle and bone size and strength have been demonstrated and were stronger in females, suggesting possible sexual dimorphism. Here we examine sex-specific associations between individual muscle sarcopenia components with clinical outcomes (falls and fractures). 641 participants were recruited. Muscle mass was assessed as cross-sectional area (CSA) by peripheral quantitative computed tomography of the calf, grip strength (GpS) by Jamar dynamometry and function by gait speed (GtS). Falls and fractures were self-reported. Ordinal and logistic regression were used to examine the associations between muscle measurements and outcomes with and without adjustment for confounders. Mean (SD) age was 69.3 (2.6) years. CSA, GpS, and GtS were greater among males (p < 0.002). A higher proportion of females had fallen since age 45 (61.3% vs 40.2%, p < 0.001); in the last year (19.9% vs 14.1%, p = 0.053); and reported a previous fracture since age 45 (21.8% vs 18.5%, p = 0.302), than males. Among females, greater CSA was related to reduced risk of falling and fewer falls in the previous year in fully adjusted analysis only (p < 0.05); higher GpS was related to lower risk of falls since age 45 in unadjusted analysis (p = 0.045) and lower risk of fracture since age 45 in both unadjusted and fully adjusted analysis (p < 0.045). No statistically significant associations were observed for GtS among either sex for any relationships between muscle measurements and clinical outcomes studied. We observed relationships between muscle mass and strength but not function with falls and fractures in females only; further longitudinal studies are required to reproduce these results.
Differenzialdiagnose reaktiver Zytopenien
Authors: Menter Thomas , Dirnhofer Stefan , Tzankov Alexandar 
Published: May 2022

ZusammenfassungReaktive Zytopenien sind eine häufige Ursache für Knochenmarkuntersuchungen einschließlich Biopsieentnahmen, insbesondere falls klinische Abklärungen und Laboranalysen (z. B. Feststellung von Substratmängeln) nicht für eine Erklärung sorgen können. Bei der Beurteilung solcher Biopsien geht es in erster Linie um den Ausschluss von Krankheiten, die die normale Hämatopoese verdrängen (Infiltrate akuter Leukämien oder Lymphome, Metastasen), um ein myelodysplastisches Syndrom zu falsifizieren, das klassischerweise zu einer ineffektiven Hämatopoese führt, oder um den Nachweis spezifischer, insbesondere infektiöser oder histiozytärer Krankheiten zu erbringen (z. B. hämophagozytierende Lymphohistiozytose).In dieser Übersicht beschreiben wir charakteristische morphologische Veränderungen reaktiver Zytopenien, fokussieren auf spezifische infektiöse und nichtinfektiöse Krankheitsbilder und grenzen sie von malignen Veränderungen, insbesondere dem myelodysplastischen Syndrom und zugrunde liegender Leukämie grossgranulärer T‑Lymphozyten, ab. Medikamenteninduzierte Veränderungen der Hämatopoese werden in einem anderen Beitrag dieser Ausgabe beschrieben.
Alterations in resting-state functional connectivity after brain posterior lesions reflect the functionality of the visual system in hemianopic patients
Authors: Gallina Jessica , Zanon Marco , Mikulan Ezequiel , Pietrelli Mattia , Gambino Silvia , Ibáñez Agustín , Bertini Caterina 
Published: May 2022

AbstractEmerging evidence suggests a role of the posterior cortices in regulating alpha oscillatory activity and organizing low-level processing in non-alpha frequency bands. Therefore, posterior brain lesions, which damage the neural circuits of the visual system, might affect functional connectivity patterns of brain rhythms. To test this hypothesis, eyes-closed resting state EEG signal was acquired from patients with hemianopia with left and right posterior lesions, patients without hemianopia with more anterior lesions and healthy controls. Left-lesioned hemianopics showed reduced intrahemispheric connectivity in the range of upper alpha only in the lesioned hemisphere, whereas right-lesioned hemianopics exhibited reduced intrahemispheric alpha connectivity in both hemispheres. In terms of network topology, these impairments were characterized by reduced local functional segregation, with no associated change in global functional integration. This suggests a crucial role of posterior cortices in promoting functional connectivity in the range of alpha. Right-lesioned hemianopics revealed also additional impairments in the theta range, with increased connectivity in this frequency band, characterized by both increased local segregated activity and decreased global integration. This indicates that lesions to right posterior cortices lead to stronger impairments in alpha connectivity and induce additional alterations in local and global low-level processing, suggesting a specialization of the right hemisphere in generating alpha oscillations and in coordinating complex interplays with lower frequency bands. Importantly, hemianopic patient’s visual performance in the blind field was linked to alpha functional connectivity, corroborating the notion that alpha oscillatory patterns represent a biomarker of the integrity and the functioning of the underlying visual system.
Topology Optimized Unit Cells for Laser Powder Bed Fusion
Authors: Boos Eugen , Ihlenfeldt Steffen , Milaev Nikolaus , Thielsch Juliane , Drossel Welf-Guntram , Bruns Marco , Elsner Beatrix A. M. 
Published: May 2022

AbstractThe rise of additive manufacturing has enabled new degrees of freedom in terms of design and functionality. In this context, this contribution addresses the design and characterization of structural unit cells that are intended as building blocks of highly porous lattice structures with tailored properties. While typical lattice structures are often composed of gyroid or diamond lattices, this study presents stackable unit cells of different sizes created by a generative design approach to meet boundary conditions such as printability and homogeneous stress distributions under a given mechanical load. Suitable laser powder bed fusion (LPBF) parameters were determined for AlSi10Mg to ensure high resolution and process reproducibility for all considered unit cells. Stacks of unit cells were integrated into tensile and pressure test specimens for which the mechanical performance of the cells was evaluated. Experimentally measured material properties, applied process parameters, and mechanical test results were employed for calibration and validation of finite element (FE) simulations of both the LPBF process as well as the subsequent mechanical characterization. The obtained data therefore provides the basis to combine the different unit cells into tailored lattice structures and to numerically investigate the local variation of properties in the resulting structures.
Bewertung alternativer Arbeitsmittel für Wärmepumpen im Gebäudesektor
Authors: Höges Christoph , Venzik Valerius , Vering Christian , Müller Dirk 
Published: May 2022

ZusammenfassungDas Arbeitsmittel in Wärmepumpen unterliegt einer Vielzahl von Anforderungen, welche für einen effizienten und sicheren Betrieb eingehalten werden müssen. Weiterhin steigt die Anzahl markterhältlicher Arbeitsmittel durch die Entwicklung neuer Gemische kontinuierlich an, wodurch deren Auswahl erschwert wird. Aus diesem Grund wird im Rahmen dieses Beitrags eine Marktanalyse alternativer Arbeitsmittel durchgeführt und die selektierten Arbeitsmittel hinsichtlich ihres Potentials für Wärmepumpen bewertet. Die Marktanalyse beinhaltet eine Einordnung der Arbeitsmittel durch politische Vorgaben (kein Ozonabbaupotential, geringes Treibhauspotential), sicherheitstechnischer Aspekte (Toxizität, Brennbarkeit) sowie technischer Anforderungen (unterkritischer Betrieb, maximale Prozesstemperaturen). Hierbei werden 32 Fluide identifiziert, welche die gestellten Anforderungen einhalten. Diese sind alle brennbar und größtenteils entweder Kohlenwasserstoffe (KW) oder Hydrofluorolefine (HFO). Anschließend wird die Effizienz im einfachen Kältekreislauf nach DIN EN 14825 bestimmt. Um die Fluidabhhängigkeit detailliert und realitätsnah abschätzen zu können, wird ein semi-physikalisches Verdichtermodell eingesetzt, welches fluid- und betriebspunktabhängige Verdichterwirkungsgrade liefert. Innerhalb der Kreislaufberechnung zeigen die Fluide RC270 und R161 die höchsten Effizienzen und führen zu einer Verbesserung der saisonalen Arbeitszahl im Vergleich zu R410A von bis zu 15 %. Diese führen aber zu hohen Temperaturen am Verdichteraustritt und sind daher ungeeignet. Weiterhin zeigen KW höhere Effizienzen als HFO. Bei der Wahl des Arbeitsmittels müssen allerdings weitere Aspekte, wie der Umwelteinfluss sowie Füllmengenbeschränkungen aufgrund der Brennbarkeit des Fluids betrachtet werden. Insgesamt weisen die Arbeitsmittel Propan und Propen das höchste Anwendungspotential auf. Für Anwendungen, in denen füllmengenbeschränkte Wärmepumpen erforderlich sind, bieten die HFO R454C, R457A und R516A effiziente Alternativen, deren Potenzial durch die Integration eines internen Wärmeübertragers in den Kältekreislauf gesteigert werden kann.