bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differential Expression of Long Noncoding RNAs in Murine Myoblasts After Short Hairpin RNA-Mediated Dysferlin Silencing In Vitro: Microarray Profiling
Authors: Singhal Richa , Lukose Rachel , Carr Gwenyth , Moktar Afsoon , Gonzales-Urday Ana Lucia , Rouchka Eric C , Vajravelu Bathri N 
Published: May 2022

Background
Long noncoding RNAs (lncRNAs) are noncoding RNA transcripts greater than 200 nucleotides in length and are known to play a role in regulating the transcription of genes involved in vital cellular functions. We hypothesized the disease process in dysferlinopathy is linked to an aberrant expression of lncRNAs and messenger RNAs (mRNAs).

Objective
In this study, we compared the lncRNA and mRNA expression profiles between wild-type and dysferlin-deficient murine myoblasts (C2C12 cells).

Methods
LncRNA and mRNA expression profiling were performed using a microarray. Several lncRNAs with differential expression were validated using quantitative real-time polymerase chain reaction. Gene Ontology (GO) analysis was performed to understand the functional role of the differentially expressed mRNAs. Further bioinformatics analysis was used to explore the potential function, lncRNA-mRNA correlation, and potential targets of the differentially expressed lncRNAs.

Results
We found 3195 lncRNAs and 1966 mRNAs that were differentially expressed. The chromosomal distribution of the differentially expressed lncRNAs and mRNAs was unequal, with chromosome 2 having the highest number of lncRNAs and chromosome 7 having the highest number of mRNAs that were differentially expressed. Pathway analysis of the differentially expressed genes indicated the involvement of several signaling pathways including PI3K-Akt, Hippo, and pathways regulating the pluripotency of stem cells. The differentially expressed genes were also enriched for the GO terms, developmental process and muscle system process. Network analysis identified 8 statistically significant (P<.05) network objects from the upregulated lncRNAs and 3 statistically significant network objects from the downregulated lncRNAs.

Conclusions
Our results thus far imply that dysferlinopathy is associated with an aberrant expression of multiple lncRNAs, many of which may have a specific function in the disease process. GO terms and network analysis suggest a muscle-specific role for these lncRNAs. To elucidate the specific roles of these abnormally expressed noncoding RNAs, further studies engineering their expression are required.
INVESTIGAÇÃO DO SUPORTE ORGANIZACIONAL: PERCEPÇÃO DE COLABORADORES DE UMA COOPERATIVA DO RIO GRANDE DO SUL
Authors: Oliveira Ramadam Amanda , Barros Estivalete Vania de Fátima , Da Silva Wegner Roger , Parcianello José Adroaldo 
Published: May 2022

Objetivo: Este estudo tem como objetivo elencar as prioridades referentes a percepção de suporte organizacional sob a perspectiva dos colaboradores de uma cooperativa do ramo agropecuário localizada no Rio Grande do Sul.
Método / abordagem: Realizou-se uma pesquisa quantitativa e descritiva com 262 colaboradores de uma cooperativa agropecuária. Como instrumento de coleta de dados foi utilizada a escala de Escala de Percepção de Suporte Organizacional, versão reduzida (EPSO-R), desenvolvida por Queiroga, Brandão e Borges-Andrade (2015). O método Analytic Hierarchy Process (AHP) foi utilizado com o objetivo de elencar os critérios e subcritérios mais importantes sob a percepção dos colaboradores investigados.
Principais resultados: Como principais resultados observa-se que os colaboradores priorizaram as “Práticas de promoção e recompensas”, principalmente no que concerne às recompensas simbólicas e materiais, a cooperativa preocupa-se também em garantir equipamentos e materiais necessários ao desempenho eficaz de suas tarefas e conceder gratificações aos seus colaboradores a título de participação nos lucros e resultados (PLR). Os colaboradores também priorizaram o “Suporte material ao desempenho”, esta ação demonstra que a cooperativa investigada fornece aos indivíduos um ambiente adequado e confortável para a realização das atividades rotineiras.
Contribuições metodológicas / sociais / gerenciais: Verificou-se que a cooperativa promove o reconhecimento dos seus colaboradores e estimula o desenvolvimento de novas ideias. Dada a significância dessas organizações, nota-se a importância de compreender os elementos priorizados pelos colaboradores em relação ao suporte organizacional nas cooperativas do ramo agropecuário.
Originalidade / relevância: Ressalta-se que essa pesquisa abre caminho para destacar a importância da temática de suporte organizacional para área de gestão de pessoas e comportamento organizacional no contexto das cooperativas.
O DEVIR-PERIFERIA DO MUNDO: CRISE DO CAPITAL E A CONDIÇÃO PERIFÉRICA
Authors: Canettieri Thiago 
Published: May 2022

O presente artigo pretende sugerir uma interpretação para o atual momento da reprodução do capital que parece engendrar uma condição específica, uma espécie de novo tempo do mundo, em que o front de defesa para a sobrevivência do capital não se restringe apenas à fábrica, mas, ao contrário, explode e implode, alcançando a totalidade do espaço social inteiro. Este momento gera (i) uma forma específica de produção do espaço marcada pela precariedade; (ii) uma forma de vida cotidiana talhada por uma experiência danificada; e (iii) uma forma de dominação social que alcança toda a esfera da vida. Diante dessas confluências, o artigo sugere a ideia de condição periférica capaz de captar o predicamento deste tempo.
INJUSTIÇA TERRITORIAL NO RIO DE JANEIRO E A EXPERIÊNCIA DA REDE INTERSETORIAL DO CAJU
Authors: Almeida de Abreu Andre 
Published: May 2022

O presente artigo resulta do esforço em busca da produção de um estudo sobre a justiça territorial munido de ancoragem empírica, utilizando-se da pesquisa de tipo qualitativo. O intuito da análise é compreender o papel da Rede Intersetorial do Caju na busca por justiça territorial no bairro situado na zona portuária do Rio de Janeiro, marcado por uma estrutura territorial injusta. Utilizando-se do estudo das redes políticas territoriais, busca-se compreender a articulação entre os atores envolvidos e da rede política territorial em questão com o poder público municipal. O estudo inclui também uma análise sobre o papel de reforço das injustiças territoriais que a estigmatização dos territórios periféricos produz, com efeito nocivo sobre a atuação do poder público no bairro do Caju. Identificamos que o desafio é desenvolver, no Caju, processos de governança territorial local que tenham como premissa a participação comunitária, a confiança e o controle democrático e que seu horizonte seja o da justiça territorial.

Palavras-chave: justiça territorial; redes políticas; Rio de Janeiro.
A EDUCAÇÃO ESCOLAR QUILOMBOLA E O ENSINO DE GEOGRAFIA EM VILA NOVA JUTAÍ – BREU BRANCO – PA
Authors: Alves dos Santos Robson , Coelho da Paixão Karleison , Laurindo dos Santos Luciano , Silva Araújo Amarildo , Eduardo Ribeiro Rocha Carlos , Vinicius Mariano de Souza Marcus 
Published: May 2022

Em um país marcado pela diversidade étnico-racial, com um extenso legado de preconceitos e negação de direitos básicos, é necessária a projeção de uma educação diferenciada e afirmativa, que se entrelace com saberes históricos e cotidianos e que desenvolva posturas críticas a partir das vozes dos quilombolas, quase sempre silenciadas. O artigo aborda a educação escolar formal, especificamente sobre o ensino de geografia na educação escolar quilombola na comunidade remanescente quilombola de Vila Nova Jutaí – Breu Branco – PA. Assim, foi desenvolvido na escola da comunidade o projeto “Nós Propomos”, que buscou identificar quais são os principais problemas socioespaciais da comunidade. A pesquisa foi baseada em levantamento bibliográfico, execução do projeto, aplicação de questionários e formulário de entrevistas. A geografia enquanto ciência e disciplina escolar tem um legado histórico de contribuição ao processo de construção da cidadania, através da análise crítica que desenvolve nos estudantes a respeito do espaço geográfico, oportunizando-os a compreenderem as dinâmicas e transformações socioespaciais.
Palavras-chave: Cultura. Territorialidades. Quilombolas. Educação.
Kinerja Keuangan Daerah dan Hubungan dengan SilPA di Kabupaten Bungo
Authors: H. Izudin H.Izudin , Syaparuddin Syaparudin , Syamsuddin HM Syamsuddin HM 
Published: May 2022

Budget Revenues and Expenditures should be managed properly and correctly, noted that financial management shall indicator of the success of the viewable area if the area of financial performance have been implemented effectively and efficiently, the impact of the effectiveness and efficiency of lead remaining in Over Budget Calculation known pleased with SiLPA, for the author want to know the district noted that financial performance is connected dengnan Bunge Silpa with the aim of (1) determine the relationship of SiLPA Revenue Bungo Regency period 2001-2010 (2) to determine the relationship Silpa-forming component with the period 2001-2010 SiLPA Bungo district, (3) to determine effectiveness and efficiency of financial management Bungo district in 2001-2010, and (4) to determine whether the effectiveness and efficiency affects the Silpa. Data analysis methods used in this study is the analysis of secondary data from Government Financial Statements consisting of Bungo District Budget Realization report, Balance Sheet, Statement of Cash Flow from Revenue Management Agency Regional Finance and Asset District Bungp years 2001-2010 and data derived from the Regional Planning Board Bungo District. By using the formula analysis korelaisi and regression Karl Person's and the analysis of the ratio obtained (1) The relationship of income of Regional against SiLPA is in the category of very low, low and medium, (2) The relationship components of SiLPA with SiLPA is in the category of moderate, strong and very strong, (3) The effectiveness of financial management are in the category of effective and very effective., for efficiency is in the category are not efficient, less efficient and reasonably efficient (4) Effect of the effectiveness of 1.419 means SiLPA event of excess revenue will mempengeruhi SiLPA increased by 1.42 percent and the efficiency of minus 0.389 SiLPA mean if there is a reduction / savings will affect the increase in spending of 0.39 percent SiLPA. Keywords: SiLPA, Budget, Financial Management
Faktor-Faktor yang Mempengaruhi Kemiskinan dan Pengangguran di Kota Jambi
Authors: Harlik Harlik , Amir Amri , Hardiani Hardiani 
Published: May 2022

The purpose of this study was : (1) To analyze the factors that affect poverty in the City of Jambi during the period 2000-2011, (2) To analyze the factors causing high unemployment in the city of Jambi during the period 2000-2011, and (3) To analyze the relationship between poverty and unemployment in the city of Jambi during the period 2000-2011. The data used in this study is secondary data from the years 2000-2011. BPS data sources derived from the city of Jambi and Diskakertrans city of Jambi. Analysis tools used in this research is a method of multiple linear regression and correlation. The results showed that: (1). Simultaneously (together) variable population density, education level and the unemployment rate, and a significant positive effect on the level of poverty in the city of Jambi. While partially independent variables that significantly influence the level of education level and the level of poverty is unemployment. Variables influence population density, education level and the unemployment rate is equal to the poverty rate of 92,40 percent, (2). Simultaneously (together) variable education level and health level have positive and significant effect on the unemployment rate in the city of Jambi. While partially independent variables had significant effect on the unemployment rate in the City of Jambi is education level. Variables influence education level and health level rate is equal to the unemployment rate of 42,6 percent; (3). Levels of poverty and unemployment rate in the city of Jambi has a negative correlation with a correlation coefficient of -0.290.
Keywords: Population Density, Unemployment Rate, Education Level
Analisis Pendapatan dan Pola Pengeluaran Rumah Tangga Miskin Di Kabupaten Sarolangun
Authors: Bahrun Bahrun , Syaparuddin Syaparuddin , Hardiani Hardiani 
Published: May 2022

The purpose of the research entittled ’An Analysis of Income and Expenditure Patterns of the Poor Households di Sarolangun Regency’, they are: First, to analyze the poor households income in Sarolangun Regency. Second, to analyze the education level of the poor households in Sarolangun Regency. Third, to analyze the expenditure pattern of the poor households in Sarolangun Regency. Forth, to analyze the poor households income’s inequality in Sarolangun Regency. The result of the research shows that, First; the monthly average of poor households income in Sarolangun Regency is Rp.852.057,- each family. Second, in the education level point of view, 90,6% of the poor household only completed their Elementary School. Third, in the expenditure-pattern point of view, in average, the expenditure-pattern of 72,96% poor households in Sarolangun Regency spent their income in food consumption, other 12,07% spent their income in primary needs (electricity, gas, water) and the rest 14,97% for vary. It is indicate that the expenditure pattern of poor households in Sarolangun Regency still concern to the primary consumption. Fourth, the poor households income’s inequality in Sarolangun Regency in average is 0,30. Keywords: primary need, expenditure pattern, income’s inequality
Analisis Sektor Basis dalam Hubungannya dengan Penyerapan Tenaga Kerja di Kabupaten Batang Hari
Authors: Syaiful Syaiful , Syaparuddin Syaparuddin , Artis Dearmi 
Published: May 2022

The purpose of the study is to (1) analyze the economy sector which become basis sector with its development rates in Batang Hari Regency, (2) the correlation between the developments of basis sector with employment and to (3) analyze the policy of local government on developing that basis sector through bibliography methods on secondary PDRB data according to constant price 2000 of Batang Hari Regency and Jambi Province from 2003 to 2012 and also employment data in the same periods and regency. This analysis uses Location Quotient (LQ) model and Dynamic Location Quotient (DLQ) model. Whereas the correlation between the developments of basis sector with employment uses Pearson’s Coefficient Of Correlation. The output of LQ analysis shows that there are four economy sectors as basis sector (LQ >1) in Batang Hari, which are agricultures, industry and manufactures, trades, hotels, restaurants, and another distinction service. While from the DLQ analysis, there are four sectors identified can be a basis sector in the future (DLQ >1), which are mining and excavation, electricity, gases and fresh water, transportation and communications, and distinction sectors. Only distinction sector which is identified as basis sector nowadays as well as in the future. From the study of the PDRB rate in Batang Hari from 2003 to 2013 shows that average growth rate of agriculture, industry and manufactures, trades, hotels and restaurants are relatively smaller than other sectors in Batang Hari, excluding distinction sectors which are higher. Pearson’s Coefficient Of Correlation analysis evinces there only two basis sectors which its growth has a strong and positive correlation with employment in Batang Hari, which are distinction and trades with hotels and restaurants. The PDRB growth of these sectors moving in the direction of the employment rates. In the agriculture and manufacture industry sectors, the correlation with employment is low and very weak. Keywords: competitive, basis sector, agriculture, manufacture
Penerapan Sistem Tanam Legowo Usahatani Padi Sawah dan Kontribusinya Terhadap Pendapatan dan Kelayakan Usaha di Kecamatan Dungaliyo Kabupaten Gorontalo
Authors: Rauf Asda , Murtisari Amelia 
Published: May 2022

Abstrak Penelitian ini bertujuan untuk mengetahui pengaruh sistem tanam padi sawah Legowo terhadap pendapatan petani padi dan kelayakan usahatani padi. Lokasi penelitian di Kecamatan Dungaliyo Kabupaten Gorontalo. Penelitian menggunakan metode survei. data primer diperoleh dari sampel petani dengan menggunakan panduan wawancara. Hasil penelitian menemukan bahwa penerapan sistem tanam legowo 4:1 menghasilkan pendapatan Rp 21.844.604 / ha, dan sistem tanam legowo 2:1 menghasilkan pendapatan sebesar Rp 21.705.833 / ha. Kelayakan padi tanam pertanian sistem legowo 4: 1 = 2.16 dan 2: 1 = 2.63. Kedua sistem tanam legowo adalah layak diterapkan untuk padi pertanian padi. Kata kunci : Sistem tanam legowa, pendapatan petani, kelayakan usaha tani Abstract This study aims to determine the effect of lowland rice cropping system Legowo on farmers' income and eligibility paddy rice. Location research in Subdistrcit Dungaliyo Subdistrict, District of Gorontalo. Research using survey method. primary data obtained from a sample of farmers using an interview guide. The results found that the application of the system of planting Legowo 4: 1 generates a revenue of Rp 21,844,604 / ha, and cropping systems legowo 2: 1 generate a revenue Rp 21,705,833 / ha. Feasibility of transplanting rice farming system legowo 4:1 = 2.16 and 2:1 = 2.63. Both legowo cropping system is feasible for paddy rice farming. Keywords: Legowo cropping system , farm income, farming feasiliblity
Faktor-Faktor Yang Mempengaruhi Penyerapan Tenaga Kerja Pada Usaha Mikro, Kecil dan Menengah (UMKM) di Kota Jambi
Authors: Syuhada Siti , Tasman Aulia , Hardiani Hardiani 
Published: May 2022

Abstrak Penelitian ini bertujuan untuk menganalisis faktor-faktor yang mempengaruhi kesempatan kerja dan faktor yang paling dominan dalam mempengaruhi penyerapan tenaga kerja pada usaha mikro dan kecil menengah (UMKM) di Kota Jambi. Metode analisis data adalah model regresi linier berganda (OLS), dengan menggunakan data sekunder time series dari tahun 1993-2010 yang bersumber dari Badan Pusat Statistik (BPS) dan Kota Jambi Bank Indonesia. Hasil analisis menunjukkan bahwa upah riil memiliki efek negatif yang signifikan terhadap kesempatan kerja dan pembentukan modal tetap bruto dan memiliki pengaruh positif dan signifikan terhadap kesempatan kerja pada usaha mikro di kota Jambi. Tingkat bunga riil memiliki efek signifikan negatif dan upah regional riil memiliki pengaruh positif yang signifikan. Variabel upah riil lebih dominan dalam mempengaruhi kesempatan kerja pada UMKM di kota Jambi.. Kata kunci : Upah riil, Tingkat bunga riil, Pembentukan Modal Tetap Bruto,. Abstract The purpose of this study was to analyze the factors that affect employment and the most dominant factor in influencing the labor absorption in the small micro and medium enterprises in the city of Jambi. Methods of data analysis used in this research is the model of multiple linear regression (OLS), by using data from the years 1993-2010 time series derived from the Central Statistics Agency (BPS) and Bank Indonesia Jambi. The results of data analysis showed that real wages and a significant negative effect on employment in micro and gross fixed capital formation has positive and significant impact on employment in micro businesses in the town of Jambi. The real interest rate significant negatif and the regional real wages in small and medium enterprises in the city of Jambi has positive and significant. Variable the real wage is more dominant in affecting employment in micro, small and medium enterprises in the town of Jambi. Keywords: real wages, real interest rates, and gross fixed capital formation
Potensi Penerimaan Pajak Bumi dan Bangunan Sektor Perdesaan dan Perkotaan di Kabupaten Batang Hari
Authors: Putra Rama Adi , Delis Arman , Hodijah Siti 
Published: May 2022

This research aims at looking at levels of growth, contribution, potency and projection of income from Land and Building Tax (PBB) in rural and urban sectors in Batang Hari Distric. The analysis instruments used are : growth, contribution, potency analysis and projection. Analysis result shows that the average of income growth of Land and Building Tax in rural and urban sectors since observation period is 9,67% ; and the contribution of Land and Building Tax in rural and urban sectors to Budget of Local revenue and Expenditure (APBD) is only in the average of 0,89%, meaning that it is still low. Whereas the average targetted is 59,34% of the known potency. This means that the target can be increased. Furthermore, in accordance with estimates projection result for 2014-2020 get increased. This means that the income prospect will continuonsly increase The growth of income will be better if data collection is accurately carried out every year ; human resources of this division is increased; and coordination is continuously improved.
Dampak Pemberian Subsidi Produksi Terhadap Keseimbangan Pasar pada Pasar Persaingan Sempurna dan Pasar Monopoli
Authors: Hardiani Hardiani , Umiyati Etik 
Published: May 2022

Abstract. This study aimed to analyze: (1) the impact of subsidies on the market equilibriumin perfect competition and monopoly markets (2) the impact of subsidies on the efficiency of markets, surplus buyer-seller on the market perfect competition and monopoly market. Research using method of experimental economics. The simulated market in the form of a) a perfectly competitive market with goods subsidized and non-subsidized goods; b) a monopoly market with goods subsidized and non-subsidized goods. Data were analyzed at each simulation and the market structure of each type of goods. The result showed that: (1) Empirical equilibrium price higher than the market monopoly of perfect competition and the higher the subsidy conditions than non-subsidized either on transaction systems double action or decentralization; (2) market with subsidized monopoly has a level of market efficiency is better than a perfectly competitive market both with and without subsidies; (3) The allocation of the surplus on the market almost entirely monopoly enjoyed by the seller. In contrast to the perfectly competitive market, relatively more surplus enjoyed by the buyer, but the difference is not too great. Keywords: experimental economics, monopoly market, perfect competition market, subsidies Abstrak. Penelitian ini bertujuan untuk menganalisis: (1) dampak subsidi terhadap keseimbangan pasar pada pasar persaingan sempurna dan pasar monopoli (2) dampak subsidi terhadap efisiensi pasar, surplus pembeli-penjual pada pasar persaingan sempurna dan pasar monopoli. Penelitian menggunakan metode percobaan ekonomi. Pasar disimulasi dalam bentuk a) pasar persaingan sempurna dengan barang non subsidi dan barang subsidi desentralisasi; b) pasar monopoli dengan barang non subsidi dan barang subsidi desentralisasi. Data yang diperoleh dianalisis pada masing-masing simulasi struktur pasar dan pada masing-masing jenis barang. Dari hasil penelitian didapatkan bahwa: (1) Harga keseimbangan empiris lebih tinggi pada pasar monopoli dibandingkan persaingan sempurna dan lebih tinggi pada kondisi subsidi dibandingkan non-subsidi baik pada sistem transaksi double action ataupun desentralisasi; (2) Pasar monopoli dengan subsidi memiliki tingkat efisiensi pasar lebih baik dibandingkan pasar persaingan sempurna baik dengan subsidi maupun tanpa subsidi; (3) Alokasi surplus pada pasar monopoli hampir seluruhnya dinikmati oleh penjual. Sebaliknya pada pasar persaingan sempurna, surplus relatif lebih banyak dinikmati oleh pembeli, tetapi dengan selisih yang tidak terlalu besar. Kata Kunci: Ekonomi Percobaan, Pasar Monopoli, Pasar Persaingan Sempurna, Subsidi