bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fully Automated MRI Segmentation and Volumetric Measurement of Intracranial Meningioma Using Deep Learning
Authors: Kang Ho , Witanto Joseph Nathanael , Pratama Kevin , Lee Doohee , Choi Kyu Sung , Choi Seung Hong , Kim Kyung‐Min , Kim Min‐Sung , Kim Jin Wook , Kim Yong Hwy , Park Sang Joon , Park Chul‐Kee 
Published: July 2022

BackgroundAccurate and rapid measurement of the MRI volume of meningiomas is essential in clinical practice to determine the growth rate of the tumor. Imperfect automation and disappointing performance for small meningiomas of previous automated volumetric tools limit their use in routine clinical practice.PurposeTo develop and validate a computational model for fully automated meningioma segmentation and volume measurement on contrast‐enhanced MRI scans using deep learning.Study TypeRetrospective.PopulationA total of 659 intracranial meningioma patients (median age, 59.0 years; interquartile range: 53.0–66.0 years) including 554 women and 105 men.Field Strength/SequenceThe 1.0 T, 1.5 T, and 3.0 T; three‐dimensional, T1‐weighted gradient‐echo imaging with contrast enhancement.AssessmentThe tumors were manually segmented by two neurosurgeons, H.K. and C.‐K.P., with 10 and 26 years of clinical experience, respectively, for use as the ground truth. Deep learning models based on U‐Net and nnU‐Net were trained using 459 subjects and tested for 100 patients from a single institution (internal validation set [IVS]) and 100 patients from other 24 institutions (external validation set [EVS]), respectively. The performance of each model was evaluated with the Sørensen‐Dice similarity coefficient (DSC) compared with the ground truth.Statistical TestsAccording to the normality of the data distribution verified by the Shapiro–Wilk test, variables with three or more categories were compared by the Kruskal–Wallis test with Dunn's post hoc analysis.ResultsA two‐dimensional (2D) nnU‐Net showed the highest median DSCs of 0.922 and 0.893 for the IVS and EVS, respectively. The nnU‐Nets achieved superior performance in meningioma segmentation than the U‐Nets. The DSCs of the 2D nnU‐Net for small meningiomas less than 1 cm3 were 0.769 and 0.780 with the IVS and EVS, respectively.Data ConclusionA fully automated and accurate volumetric measurement tool for meningioma with clinically applicable performance for small meningioma using nnU‐Net was developed.Evidence Level3Technical EfficacyStage 2
Synesthetes are More Involved in Art — Evidence From the Artistic Creativity Domains Compendium (ACDC)
Authors: Lunke Katrin , Meier Beat 
Published: July 2022

ABSTRACTCreativity is a multidimensional, multistage, and time‐dependent process, which can be expressed in various artistic domains and sub‐domains (e.g., visual arts, literature, music, and performing arts). The present study investigated the involvement of synesthetes in art, and whether the type of synesthesia determines the preferred artistic domain. We tested 709 participants with either grapheme‐color, sound‐color, or sequence‐space synesthesia (monotypical synesthesia) or a combination thereof (multiple synesthesia) and non‐synesthete controls with the Artistic Creativity Domains Compendium (ACDC). The ACDC measures the involvement in art on the three levels “interest,” “ability,” and “performance” for the four domains “visual arts,” “literature,” “music,” and “performing arts.” Overall, the results showed that synesthetes have an affinity for all four artistic domains compared with non‐synesthete controls. Moreover, the presence of multiple types of synesthesia affected the specific preference. Besides, compared with monotoypical synesthetes, the group of grapheme‐color‐sound‐color‐and‐sequence‐space synesthetes showed higher involvement in all artistic domains, most pronounced in visual arts. Overall, the study demonstrates that synesthesia is associated with higher interest, ability, and performance in art.
Microlaryngeal Laser Surgery Using High‐flow Nasal Ventilation at Two Oxygen Concentration Deliveries
Authors: Novakovic Daniel , Sheth Meet , Fellner Avital , Zoszak Alexander , Liew Stefan , Nguyen Duy Duong 
Published: July 2022

ObjectivesVentilation using 100% oxygenation creates a risk of fire during laser microlaryngeal surgery (MLS). The purpose of this study is to describe the technique of transnasal high‐flow ventilation using laser safe (30%) oxygen conditions, measure the intraoperative real‐time laryngeal oxygen concentration, and examine patient saturation status using this technique.MethodsProspective IRB approved study of patients undergoing tubeless laser MLS using high‐flow nasal oxygenation. Delivered oxygen concentration was reduced from 100% to 30% before lasering using an oxygen‐air blender then increased to 100% post‐laser procedure. Outcome measures included time for laryngeal oxygen concentration to equalize to laser safe levels; time to, methods of and duration of rescue ventilation; and desaturation rates and apnoeic times at both 100% and 30% oxygen deliveries.ResultsFifty patients were recruited (mean age = 47.4 years). Mean laryngeal oxygen concentration (%) at 100% and 30% deliveries was 98.46 and 31.45, respectively. Mean (SD) of laryngeal oxygen concentration equalization time to 30% (seconds) was 9.4 (3.69). At 30% oxygen delivery desaturation rate was faster and apneic time shorter compared with 100%. Eighteen patients required rescue (jet) ventilation and they had a faster apneic desaturation rate (%/minute) than patients not requiring rescue. Mean (SD) apneic time (minutes) at 30% delivery was 4.56 (2.25) and 4.41 (2.18) in rescue versus non‐rescue groups respectively. BMI was the only significant predictor of desaturation rate at 30% oxygen delivery.ConclusionIt is possible to achieve a safe time window for use of laser during MLS using transnasal humidified high‐flow ventilation by delivering 30% oxygen concentration.Level of Evidence4 Laryngoscope, 133:634–639, 2023
Influence of Al content and low oxygen pressure preoxidation on high‐temperature oxidation resistance of Ni–25Cr–xAl–1Si–0.5Y alloys
Authors: Li Danhong , Wang Kun , Zhu Xiangying , Chen Junxiu , Liu Ya , Wang Jianhua , Su Xuping 
Published: July 2022

AbstractThe influence of Al content and low oxygen pressure preoxidation on the high‐temperature oxidation resistance of the Ni–25Cr–xAl–1Si–0.5Y (x = 0, 1, 3, 5 wt%) alloys were studied. The formation of oxides in low oxygen pressure preoxidation was investigated. The oxidation behavior of alloys with different Al content at 1000°C with and without preoxidation under low oxygen pressure was discussed. A protective oxide film was formed on the surface of alloys with different Al content in low oxygen pressure pre‐oxidation at 950°C for 5 h, but there were great differences in microstructures and properties. With the increase of Al content, the outermost oxide film of the alloy gradually changed from continuous Cr2O3 to Al2O3, and the oxidation resistance of the alloy increased gradually at 1000°C. By comparison, the oxidation resistance of Ni–25Cr–xAl–1Si–0.5Y (x = 0, 1, 3, 5 wt%) alloys can be significantly improved at 1000°C by low oxygen pressure preoxidation treatment.
Study of Ion Transport in Novel Protic Polymerized Ionic Liquids and Composites
Authors: Huang Gongyue , Zhu Haijin , Porcarelli Luca , García Yady , O'Dell Luke A. , Forsyth Maria 
Published: July 2022

AbstractIn this work, a novel protic polymerized ionic liquid [PSTFSI][Im] is synthesized. The [PSTFSI][Im] polymer presents moderate ionic conductivity and evidences proton activity. Incorporating protic ionic liquid (Protic IL) [MIm][TFSI], the composites present enhanced ionic conductivity, up to 10−3 S cm−1 at 120 °C upon addition of 60 wt% [MIm][TFSI]. It is found that the [PSTFSI][Im] polymer matrix can promote ion dissociation of the [MIm][TFSI] IL, leading to a larger cation/anion relative mobility compared to the neat Protic IL. This work demonstrates the potential of protic PolyIL as a polymer matrix for proton conductors.
Case report of bilateral ovarian fibromas associated with de novo germline variants in PTCH1 and SMARCA4
Authors: Higashimoto Tomoyasu , Smith Christy Haakonsen , Hopkins Mark R. , Gross John , Xing Deyin , Lee Jae W. , Morris Traevia , Bodurtha Joann 
Published: July 2022

AbstractBackgroundOvarian sex cord‐stromal tumors (OSCTs) are rare ovarian tumors that can develop from sex cord, stromal cells, or both. OSCTs can be benign or malignant. Bilateral and/or unilateral ovarian fibromas, a type of OSCT of the stromal cells, have been reported in individuals diagnosed with nevoid basal cell carcinoma syndrome (NBCCS). Calcified ovarian fibromas have been reported in 15–25% of individuals diagnosed with NBCCS while 75% of those cases occur bilaterally. The average age at diagnosis of OSCT/ovarian fibromas in patients with NBCSS is in the second to third decade compared with age 50 in the general population. Ovarian tumors are rare in pediatric populations.MethodsThe patient is a 5‐year‐old female diagnosed with bilateral ovarian fibromas at age 4. Multigene panel for the patient and subsequent targeted molecular evaluation of parents were completed. Histological evaluations on the surgically resected ovaries were performed for microscopic characterization of fibromas.ResultsGermline testing identified de novo heterozygous novel likely pathogenic variants in PTCH1 gene, exon 12 deletion, and an SMARCA4 splicing variant c.2002‐1G > A. Microscopic examination of bilateral tumors was consistent with an ovarian fibroma.ConclusionsTo our knowledge, this is the first report of bilateral benign ovarian fibroma in a child with a diagnosis of nevoid basal cell carcinoma syndrome (NBCCS) with a potential predisposition to Rhabdoid Tumor Predisposition Syndrome (RTPS).
Physiological and metabolic aspects of follicular developmental competence as affected by lactational body condition loss
Authors: Costermans Natasja G. J. , Teerds Katja J. , Kemp Bas , Keijer Jaap , Soede Nicoline M. 
Published: July 2022

AbstractMetabolic demands of modern hybrid sows have increased over the years, which increases the chance that sows enter a substantial negative energy balance (NEB) during lactation. This NEB can negatively impact reproductive outcome, which is especially evident in primiparous sows causing a reduced second parity reproductive performance. The negative effects of the lactational NEB on reproductive performance can be partly explained by the influence of the premating metabolic state, during and after lactation, on the development of follicles from which oocytes will give rise to the next litter. In addition, the degree and type of body tissue mobilization during lactation that is, adipose tissue or lean mass, highly influences follicular development. Research investigating relations between the premating metabolic state and follicular and oocyte competence in modern hybrid sows, which experience higher metabolic demands during lactation, is limited. In this review we summarize current knowledge of physiological relations between the metabolic state of modern hybrid sows and follicular developmental competence. In addition, we discuss potential implications of these relations for current sow management strategies.
Changes in body weight, health behaviors, and mental health in adults with obesity during the COVID‐19 pandemic
Authors: Almandoz Jaime P. , Xie Luyu , Schellinger Jeffrey N. , Mathew M. Sunil , Marroquin Elisa Morales , Murvelashvili Natia , Khatiwada Shreeya , Kukreja Sachin , McAdams Carrie , Messiah Sarah E. 
Published: July 2022

AbstractObjectiveThe aim of this study was to examine the relationships between body weight changes, health behaviors, and mental health in adults with obesity during the second year of the COVID‐19 pandemic.MethodsBetween March 1, 2021, and November 30, 2021, adults from three obesity practices completed an online survey. The primary outcomes were ≥ 5% of body weight change since March 2020 and associated health behaviors and mental health factors.ResultsThe sample (n = 404) was 82.6% female (mean age 52.5 years, mean BMI 43.3 kg/m2). Mean weight change was + 4.3%. Weight gain ≥ 5% was reported by 30% of the sample, whereas 19% reported ≥ 5% body weight loss. The degree of both weight gain and weight loss correlated positively with baseline BMI. Eighty percent of the sample reported difficulties with body weight regulation. Those who gained ≥ 5% versus those who lost ≥ 5% body weight were more likely to report higher levels of stress, anxiety, and depression; less sleep and exercise; less healthy eating and home‐cooked meals; and more takeout foods, comfort foods, fast foods, overeating, and binge eating.ConclusionsWeight gain in adults with obesity during the COVID‐19 pandemic is associated with higher baseline BMI, deteriorations in mental health, maladaptive eating behaviors, and less physical activity and sleep. Further research is needed to identify effective interventions for healthier minds, behaviors, and body weight as the pandemic continues.image
Engineering the surface properties of bamboo scrimber to enhance the gluing properties
Authors: Wu Jiangyuan , Zhang Yahui , Ji Yaohui , Zhu Rongxian , Sun Yuhui , Yu Yanglun , Yu Wenji 
Published: July 2022

AbstractThe adhesive ability of bamboo scrimber is critical for its use in large‐scale engineering structures. Cold‐pressed bamboo scrimber with varying sanding mesh and density was made and then bonded with polyurethane resin. The adhesive was concentrated on the surface, assisting the anchoring into the material surface. The shear strength and immersion peel strength are studied as parameters to determine the glue qualities. The optimum gluing characteristics were obtained using a 120 grit sandpaper and a density of 1.15 g/cm3. The results indicated that at a density of 1.15 g/cm3, the gluing characteristics rose initially and subsequently dropped as the number of sanding meshes increased. The bonding strength improved with increasing density when 120‐mesh sanding was used. With increasing density, the bamboo fiber distribution inside the material got more compact, while the resin dispersion became more uniform. Thus, the surface porosity and roughness were decreased.
Design, preparation, and characterization of silk fibroin/carboxymethyl cellulose wound dressing for skin tissue regeneration applications
Authors: Farshi Paniz , Salarian Reza , Rabiee Mohammad , Alizadeh Sanaz , Gholipourmalekabadi Mazaher , Ahmadi Sepideh , Rabiee Navid 
Published: July 2022

AbstractSilk fibroin (SF) has been broadly applied in wound dressing fabrication because of its proper features for wound healing. In this work, we developed a carboxymethyl cellulose (CMC)/gelatin blend film with different concentrations of glycerol, and modified the optimized film with an SF layer through electrospinning process. Tensile strength and cell viability evaluation of blend films demonstrated that the glycerol content of 3% could be suitable as the substrate layer for the two‐layer wound dressing. The morphology of the blend film and electrospun nanofibers was obtained from scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR). It concluded that structural changes had been occurred in both layers after cross‐linking with glutaraldehyde vapor. Further, it was shown that the mechanical properties of the two‐layer enhanced with the addition of SF. Moreover, the swelling ratio was higher than those of SF itself, due to the hydrophilic property of CMC/gelatin blend film. The biocompatibility of fibroblasts was investigated by MTT assay, and the coating showed an improvement in cell proliferation because of the cytocompatibility nature of SF. All results suggest that the prepared wound dressing could be a desirable candidate for wound healing applications.
Von Wasserstoff bis Eisen, Nickel und Zink
Authors: Thielemann Friedrich‐Karl 
Published: July 2022

ZusammenfassungDie Entstehung der Elemente im Kosmos findet in einer Vielzahl astrophysikalischer Umgebungen statt. Diese umfassen den Urknall, Sterne mit geringer und mittlerer Masse sowie massereiche Sterne. Beiträge während der Entwicklung von Galaxien erfolgen durch abgeblasene Winde während der Sternentwicklung und durch Explosionen an ihrem Ende. In diesem Teil I zur kosmischen Nukleosynthese ist der Beitrag von Doppelsternsystemen – wie Typ‐Ia‐Supernovae aus explodierenden Weißen Zwergen mit viel Fe‐Produktion – nicht berücksichtigt, ebensowenig wie der Ursprung der schweren Elemente. Dies wird der Schwerpunkt von Teil II sein, wo wir auch die Bedeutung von langsamen und schnellen Neutronen‐Einfangprozessen in Sternen sowie bei Supernovae und Neutronenstern‐Verschmelzungen diskutieren und einen Gesamtüberblick über die Erzeugung der verschiedenen Elemente geben werden.
Prevention of Self Decomposition in Pyrotechnic Wet Mixtures by Replacing Aluminium with Boron
Authors: Prakash Lakshmana Pandian , Azhagurajan Arumugachamy , Jeyasubramanian Kadarkaraithangam 
Published: July 2022

AbstractIn fireworks industries, water‐added mixtures like tip mixtures, and aerial star pellet coatings are susceptible to self‐decomposition because aluminium readily reacts with water that is used with them. While adding water to the tip mixture, the aluminium undergoes hydration and forms an oxide. It also liberates heat and hydrogen gas, which leads to an explosion. Similarly, the star pellets coated with aluminium also had the same problem. To avoid the hazard due to self‐decomposition, partial replacement of aluminium powder helps in the reduction of workplace accidents/injuries. Recently, researchers used boron as a substituent for aluminium in dry mixtures such as flash powder composition. In this work, the use of aluminium in the wet mixtures is gradually replaced with boron. The thermal analysis and the decomposition tests were conducted for the boron‐blended wet mixtures. The performance characteristics of boron‐blended tip mixtures and star pellets were evaluated to determine the optimum level of replacement to sustain the quality with improved safety.
Extended JCZ3 Equation of State and JAGUAR Implementation for High Explosives
Authors: Stiel Leonard , Baker Ernest , Samuels Philip , Cornell Rodger , Rydzewski David 
Published: July 2022

AbstractAn extended JCZ3 based equation of state for the modelling of high explosive detonation products has been implemented in the JAGUAR computer model. This development includes the parameterization of EXP‐6 potentials for individual products species, as well as mixing rules for the combination of species. Non‐linear variable metric optimization was used for the species parameterization, as well as for the solution of free energy minimized states. Explosive detonation and products expansion are typically modelled for JWL and JWLB high explosives thermodynamic equation of state development. An analytic c ylinder test model was developed for the comparison to experimental cylinder expansion test data and for the characterization of explosive products expansion and work output. Examples and comparisons to data are presented. Historically, streak photography was used for cylinder testing, whereas photon‐doppler velocimetry (PDV) is now standard. This has resulted in some changes in cylinder testing data reduction. A JAGUAR MSIAC web‐based application is currently under development for use by the MSIAC member nations.
Imputation of continuous missing values in profile data
Authors: Yang Luo , Wang Kaibo 
Published: July 2022

AbstractProfile data have been widely used in quality control practice. However, in some applications, incomplete profiles, or profiles with continuous missing values, are frequently encountered. Imputation of continuous missing values in profiles for quality control is a challenging problem. In this work, we propose a latent feature model and a two‐step learning algorithm to reconstruct missing values. In the model, an unsupervised deep‐learning technique, variational autoencoder (VAE), is utilized to learn the latent features from profile data. Then a supervised variational coding (SVC) scheme is proposed to map the incomplete profile data to the learned latent features, and imputation is then made based on the latent features. The performance of the proposed method is evaluated by simulated and real datasets, and the results prove the effectiveness and superiority of the proposed method.
Synthesis and Biological Evaluation of Substituted 3‐Isoxazolethioethers as Antileishmanial and Antibacterial Agents
Authors: Bisht Shweta , Kumar Lalan , Kaul Grace , Akhir Abdul , Saxena Deepanshi , Chopra Sidharth , Karthik R. , Goyal Neena , Batra Sanjay 
Published: July 2022

AbstractThe synthesis of substituted 3‐isoxazolethioethers and their bioevaluation as anti‐leishmanial and anti‐bacterial agents are described. The DBU‐catalyzed thioetherification of substituted 3‐nitroisoxazoles via nucleophilic aromatic substitution (SNAr) reaction using aromatic, aliphatic and heteroaromatic thiols gave the title compounds in good yields. These 3‐thioisoxazole derivatives were synthetically modified to prepare new compounds including 3‐phenylbenzo[b]isoxazolo[4,3‐f][1,4]thiazepin‐4(5H)‐ones. Four compounds displayed promising activity against amastigote stage ofL. donovaniwhereas two compounds displayed good antibacterial effect.
Isomeric D‐π‐D Dopant‐Free Hole Transport Materials: Effect of the Substitution Position and Heteroatom on the Performance of Perovskite Solar Cells
Authors: Liang Yongpeng , Wu Nan , Zhang Xianfu , Ghadari Rahim , Liu Xuepeng , Guo Fuling , Dai Songyuan 
Published: July 2022

AbstractA series of facile small‐molecular D‐π‐D HTMs with dibenzofuran or dibenzothiophene as π‐bridge, and the triarylamine groups as peripheral arms was designed and prepared. The impact of the varied substitution position of triarylamine groups on the π‐bridge and heteroatomic effect on the molecular and device properties are extensively studied. All the molecules exhibit suitable energy alignment of the HOMO with the valence band of perovskite. 3,7‐molecules showed red‐shift spectra compared to that of 4,6 and 2,8‐counterparts, indicating the better conjugation. Due to the better hole extraction and conductivity of 3,7‐molecules because of enhanced conjugation, which exhibits relatively best power conversion efficiency. 4,6‐substituents exhibit inferior device performance due to the broken conjugation of 4,6‐position and bad film‐forming ability. Moreover, the O‐based HTMs exhibit relatively better device performance when the terminal groups are located on 3,7‐position due to enhanced hole extraction ability. However, the heteroatom effect of 4,6‐substituent is contrary with 3,7‐counterpart due to the opposite conductivity change trend.