bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clear air echoes from the atmospheric boundary layer over Chennai – A study using S-band Doppler Weather Radar
Authors: SURESH R. , ARAVINDAN V. , RAO P.  RAJESH , BHATNAGAR A.  K. 
Published: January 2022

During December 2002 – early April 2003, between 2345 and 0215 UTC and between 1230 and 1400 UTC covering the twilight period, radar reflectivities as high as 28-38 dBZ were measured in the atmospheric boundary layer by the Doppler Weather Radar (DWR) installed at Cyclone Detection Radar station, Chennai regularly. On analysis, it was found that these radar returns were not from precipitating clouds but from some other invisible source(s). The contributory mechanisms for this high order of reflectivity have been analysed from meteorological and non-meteorological angles. Thermodynamical parameters and potential radio refractive index have been computed and analysed. The refractive index structure constant (Cn2) has been computed from the 0000 and 1200 UTC RS/RW data as well as from the radar reflectivity data. The prevalence of convectively unstable atmosphere in the first layer adjacent to the surface (upto 350 m a.g.l) at 1200 UTC and nocturnal surface inversion at 0000 UTC contribute to the enhanced Cn2 in the range of 3.58 ´ 10-12 to 10-15 m-2/3 in the layers upto 900 m a.g.l. This sort of Bragg scattering with high Cn2 could have contributed to radar reflectivity factor as high as +0.8 dBZ only. During the last three decades, there is an alarming increase in nocturnal surface inversion frequencies over Chennai presumably due to high concentration of suspended particulate matters and respirable dust particles. The contribution by these pollutants to the radar reflectivity factor is restricted to a maximum of about – 0.9 dBZ only. Migratory birds of about eight to twelve thousand in number with 10 – 50 cm2 radar cross section and possibly innumerable insects appear as sources of the enhanced reflectivity.
Evolution of convection anomalies over the Indo-Pacific region in relation to Indian monsoon rainfall
Authors: PATTANAIK D. R. , KALSI S. R. , HATWAR H. R. 
Published: January 2022

The present study is an attempt to explore a relationship between Indian Summer Monsoon Rainfall (ISMR) and the evolution of convective activity during winter to pre-monsoon seasons over the Indo-Pacific region. The monthly mean Outgoing Long-wave Radiation (OLR) data obtained from National Oceanic and Atmospheric Administration (NOAA) polar orbiting spacecraft are used in this study from January 1975 to May 2004. It is observed that the negative OLR (thus, convection) anomalies from January gradually strengthen in a west northwest direction from western Pacific region and got established over the southeast Asian region and adjoining eastern equatorial Indian Ocean by the month of May during excess ISMR years indicating a gradual reversal of anomalous rising motion over western Pacific in January to anomalous sinking motion in May over western Pacific region. However, during the deficient ISMR years the negative OLR anomalies established over the western Pacific region in January almost remain active over the same region till the month of May and consequently there is persistent presence of rising motion from northern winter to pre-monsoon seasons over the western Pacific.
Similar to the patterns during the deficient composite the evolution of OLR anomalies show stronger than normal convective activity over the western Pacific region east of 150° E compared to that of eastern Indian Ocean and adjoining southeast Asia from February to May during the deficient years of 1979, 1982, 1987, 2002, and 2004 though there exists strong interannual variability in its magnitude. The tendency of OLR anomalies over the western Pacific region from January to March and the difference of OLR anomalies between western equatorial Pacific and eastern Indian Ocean and adjoining southeast Asia regions in the month of May shows significant (95% level) correlation with ISMR and the predicted ISMR with these two predictors using simple regression model shows significant correlations (95% and 99% level respectively) with actual ISMR for the extreme years.
Role of cyclonic systems in excess and deficit monsoon years in India
Authors: MUTHUCHAMI A. , SRIDHARAN S. 
Published: January 2022

In this paper an attempt is made to study the rainfall features associated with cyclonic systems (Depressions and cyclonic storms) during excess and deficit monsoon years over the country. It is seen statistically that there is no significant difference in number of systems that formed during excess and deficit years. In the month of May systems travel mostly towards north in excess years whereas in deficit years they travel northwest ward. In June the formation positions during excess and deficit years have no significant difference in latitude of formation. In the case of longitude, the systems in excess monsoon years form slightly to the east compared to deficit years. In September the systems not only form at lower latitudes in deficit years but also they form close to coast in deficit years than in excess years. In September number of formation of systems in excess years is more than deficit years. El- Nino is not the major factor which controls the rainfall distribution in monsoon months.
PENGARUH ALAT MODIFIKASI BOLA GANTUNG TERHADAP KETERAMPILAN PASSING BAWAH DALAM PERMAINAN BOLA VOLI
Authors: Gustaman Candra Pardini  
Published: January 2022

Penelitian ini bertujuan untuk mengetahui Pengaruh Alat Modifikasi Bola Gantung Terhadap Keterampilan Passing Bawah dalam Permainan Bola Voli. Penelitian ini merupakan penelitian yang mengunakan deskriptif kualitatif. Teknik dalam pengumpulan data dalam penelitian ini menggunakan studi literatur yang dimana menggunakan data primer dan data sekunder. Teknik keabsahan data menggunakan triangulasi data. Hasil penelitian ini dapat disimpulkan bahwa Terdapat pengaruh alat modifikasi bola gantung terhadap keterampilan passing bawah sebelum dan sesudah pelaksanaan passing bawah bola voli dengan menggunakan alat modifikasi bola gantung. Dengan penggunaan alat modifikasi bola gantung berpengaruh secara signifikan terhadap keterampilan passing bawah dalam permaianan bola voli.
Educación remota de emergencia: experiencias de estudiantes de una unidad académica regional de la BUAP durante la pandemia de COVID-19
Authors: Romero Fernández Abelardo , Villanueva Méndez Laura , Morandín Ahuerma Fabio , Vargas Vizuet Ana Liviere 
Published: January 2022

Este estudio presenta los resultados de una investigación cuantitativa de alcance exploratorio que tuvo por objetivo recuperar y explorar las experiencias de los estudiantes de nivel licenciatura, que tuvieron que concluir el semestre de primavera 2020 por medio de clases no presenciales con los medios que disponían durante la etapa de mayor incertidumbre sobre la pandemia generada por Covid-19. Se aplicó un cuestionario con preguntas cerradas y abiertas a 124 estudiantes de las licenciaturas de Estomatología, Medicina General y Comunitaria, Nutrición Clínica y de Psicología de una unidad académica regional en la zona nororiental del Estado de Puebla. Entre los resultados se destaca que, aunque la mayoría de los estudiantes cuenta con un servicio de internet para realizar sus tareas y acceder a sus clases, se señala como problema constante para cubrir objetivos de aprendizaje la baja calidad en conexión a internet. Además, se identifica que aunque en la mayoría de los casos se revisaron los temas de los programas de estudio, los estudiantes consideraron que no se cubrieron los objetivos de aprendizaje, lo que relacionaron principalmente a la aplicación de técnicas y actividades no adecuadas para las clases no presenciales por parte de los docentes. Finalmente la falta de práctica clínica fue un elemento que presentó diferencia significativa en la licenciatura en estomatología respecto a las otras licenciaturas en el logro de objetivos de aprendizaje.
A influência da fadiga muscular de membros superiores na estabilidade manual
Authors: Nascimento Juarez Vieira do 
Published: January 2022

O objetivo deste estudo foi verificar a influência da fadi­ga muscular, de membros superiores. Na estabilidade manual de sujeitos de ambos os sexos através da realização de uma tarefa motora, foram sujeitos 20 alunos da universidade federal de santa maria/rs, voluntários, de ambos os sexos (n= 10 masc. e n= 10 fem.). a tarefa fatigante foi realizada num cicloergometro adaptado com aumento progressivo de cargas e velocidade constante de 50 rpm. a analise de variancia, teste de duncan e teste "t" de student revelaram diferen­ças significativas (p< 0. 01; _p <• 0, 05 e p< 0.01, respectivamente ) nos resultados das varaveis numero de erros e tempo de permanencia em erro das maos direita e esquerda. encontrou-se, também diferença significativa (p< 0.01) na estabilidade manual da mão direita para ambos os sexos. concluiu-se que a fadiga muscular influenciou na estabilidade manual dos sujeitos na tarefa motora proposta.
Editorial
Authors: Silva Maria Cristina da Rosa Fonseca , Fernandes Vera Penzo 
Published: January 2022

Editorial da Revista Palíndromo vol. 14 n. 32 janeiro-abril 2022
Dossiê Formação de professores de artes no brasil: problematizações a partir do projeto em rede observatório
Organizadoras:
Profa. Dra. Maria Cristina da Rosa Fonseca da Silva (UDESC)
Profa. Dra. Vera Fernandez Penzo (UFMS)
Analysis of Factors that Influence SOE'S Superior Performance with Cost Leadership as a Mediation Variable
Authors: Lestari Syarifa Yunindiah , Murwaningsari Etty , Mayangsari Sekar , Herawaty Vinola 
Published: January 2022

This study aims to analyze the factors that affect the performance of State-Owned Enterprises or BUMN. The method of determining the sample using purposive sampling, and analyze the factors that affect the performance of State-Owned Enterprises. Research is finding that the variables that affect significantly the performance of state-owned enterprises are cost leadership, leverage, capital expenditure, growth, real earnings management activities, indicators of performance management, cash flow from operating, liquidity, taxes, size, contribution margin, and revenue. The originality of the research is, is the measurement of the variable cost leadership that is based on elasticity theory, and novelty in the measurement variable indicator of the performance of the management which is based on the criteria of the activity in judging the performance of SOEs. The implication of this research is to make it easier for SOE management to achieve performance targets by taking into account the magnitude of the coefficient of influence of key variables on the performance of SOEs.
Experimental validation of a nonlinear model predictive controller regulating the acetate concentration in fed‐batch Escherichia coli BL21(DE3) cultures
Authors: Abadli Merouane , Dewasme Laurent , Tebbani Sihem , Dumur Didier , Vande Wouwer Alain 
Published: January 2022

AbstractFed‐batch cultures of Escherichia coli are commonly used for the production of biopharmaceuticals. However, productivity can be adversely affected by the production of acetate inhibiting the cell respiratory capacity. In this study, a nonlinear predictive control is developed based on a process model, and an unscented Kalman filter for estimating the evolution of the glucose and acetate concentrations. The control objective is to regulate the acetate concentration at a low level, so as to maintain the culture close to the edge between the fermentative and respirative regimes. The control strategy is tested in simulation and in lab‐scale experiments, demonstrating its feasibility and performance.
Single‐dose versus low‐dose rituximab in corticosteroid‐resistant or relapsed ITP: A multicenter, randomized, controlled study
Authors: Ni Xiaofei , Li Daqi , Yuan Chenglu , Yu Yafei , Wang Haoyi , Wang Lingjun , Yu Tianshu , Qin Ping , Peng Jun , Hou Ming , Shi Yan , Hou Yu 
Published: January 2022

AbstractPrimary immune thrombocytopenia (ITP) is an autoimmune bleeding disorder, in which rituximab (RTX) induces the best long‐term effect among recommended second‐line treatments. Nevertheless, the optimal regimen of RTX remains unclear. We herein conducted a prospective, multicenter, open‐label, randomized controlled trial to compare the efficacy and safety of RTX at two different dosage regimens in patients with corticosteroid‐resistant or relapsed ITP. Recruited patients were randomly assigned (1:1) to receive either RTX at a repeated low dose (100 mg weekly for 4 weeks, LD‐RTX) or at a single dose (375 mg/m2, S‐RTX). Overall response was achieved in 64.3% of patients who received LD‐RTX versus 67.4% of those receiving S‐RTX (p = .759). The complete response (CR) rate was 23.8% after LD‐RTX and 28.3% after S‐RTX (p = .635). In health‐related quality of life, S‐RTX improved patients' psychological status, quality of life, social activities, and work compared with LD‐RTX. Furthermore, S‐RTX significantly reduced physician visits without compromising efficacy. Our findings demonstrate that a S‐RTX is comparable to LD‐RTX in effectiveness and safety for treatment of corticosteroid‐resistant or relapsed ITP. The single‐dosage regimen optimizes the use of medical resources, improves the cost‐effectiveness of RTX, and represents a promising and more convenient replacement for LD‐RTX in ITP. This study has been completed and is registered with ClinicalTrials.gov, number NCT03258866.
Stability in BMI over time is associated with a better cognitive trajectory in older adults
Authors: Beeri Michal Schnaider , Tirosh Amir , Lin Hung‐Mo , Golan Sapir , Boccara Ethel , Sano Mary , Zhu Carolyn W. 
Published: January 2022

AbstractObjectiveEvidence on simultaneous changes in body mass index (BMI) and cognitive decline, which better reflect the natural course of both health phenomena, is limited.MethodsWe capitalized on longitudinal data from 15,977 initially non‐demented elderly from the Alzheimer's Disease Centers followed for 5 years on average. Changes in BMI were defined as (1) last minus first BMI, (2) mean of all follow‐up BMIs minus first BMI, and (3) standard deviation of BMI change from baseline and all follow‐up visits (representing variability).ResultsParticipants with significant changes in BMI (increase or decrease of ≥5%), or who had greater variability in BMI, had faster cognitive decline. This pattern was consistent irrespective of normal (BMI < 25; N = 5747), overweight (25 ≤ BMI < 30; N = 6302), or obese (BMI ≥ 30; N = 3928) BMI at baseline.ConclusionsStability in BMI predicts better cognitive trajectories suggesting clinical value in tracking BMI change, which is simple to measure, and may point to individuals whose cognition is declining.
Measurable residual disease, FLT3‐ITD mutation, and disease status have independent prognostic influence on outcome of allogeneic stem cell transplantation in NPM1‐mutated acute myeloid leukemia
Authors: Al Hamed Rama , Labopin Myriam , Daguindau Etienne , Niittyvuopio Riitta , Huynh Anne , Socié Gerard , Srour Micha , Henri Bourhis Jean , Kröger Nicolaus , Tholouli Eleni , Choi Goda , Poiré Xavier , Martin Hans , Rubio Marie‐Thérèse , Jindra Pavel , Blaise Didier , Beelen Dietrich , Labussière‐Wallet Hélène , Nagler Arnon , Bazarbachi Ali , Mohty Mohamad 
Published: January 2022

AbstractNucleophosmin‐1 (NPM1) mutations in acute myeloid leukemia (AML) confer a survival advantage in the absence of FLT3‐internal tandem duplication (FLT3‐ITD). Here, we investigated the main predictors of outcome after allogeneic hematopoietic stem cell transplantation (allo‐HCT). We identified 1572 adult (age ≥ 18 year) patients with NPM1‐mutated AML in first complete remission (CR1:78%) or second complete remission (CR2:22%) who were transplanted from matched sibling donors (30.8%) or unrelated donors (57.4%) between 2007 and 2019 at EBMT participating centers. Median follow‐up for survivors was 23.7 months. FLT3‐ITD was present in 69.3% of patients and 39.2% had detectable minimal/measurable residual disease (MRD) at transplant. In multivariate analysis, relapse incidence (RI) and leukemia‐free survival (LFS) were negatively affected by concomitant FLT3‐ITD mutation (HR 1.66 p = 0.0001, and HR 1.53, p < 0.0001, respectively), MRD positivity at transplant (HR 2.18, p < 10−5 and HR 1.71, p < 10−5, respectively), and transplant in CR2 (HR 1.36, p = 0.026, and HR 1.26, p = 0.033, respectively), but positively affected by Karnofsky score ≥90 (HR 0.74, p = 0.012, and HR 0.7, p = 0.0002, respectively). Overall survival (OS) was also negatively influenced by concomitant FLT3‐ITD (HR 1.6, p = 0.0001), MRD positivity at transplant (HR 1.61, p < 10−5), and older age (HR 1.22 per 10 years, p < 0.0001), but positively affected by matched sibling donor (unrelated donor: HR 1.35, p = 0.012; haploidentical donor: HR 1.45, p = 0.037) and Karnofsky score ≥90 (HR 0.73, p = 0.004). These results highlight the independent and significant role of FLT3‐ITD, MRD status, and disease status on posttransplant outcomes in patients with NPM1‐mutated AML allowing physicians to identify patients at risk of relapse who may benefit from posttransplant prophylactic interventions.
Coexistence of superficial carcinogenesis of resident epithelium besides neuroendocrine neoplasm of the digestive tract
Authors: Kuwano Hiroyuki , Yokobori Takehiko , Ide Munenori , Saeki Hiroshi , Sohda Makoto , Sakai Makoto , Yoshida Tomonori , Kuriyama Kengo , Ogata Kyoichi , Ogawa Hiroomi , Okada Takuhisa , Miyazaki Tatsuya , Takahashi Shunsuke , Shirabe Ken 
Published: January 2022

AbstractBackground & AimsMixed neuroendocrine–non‐neuroendocrine neoplasm (MiNEN) is a rare neuroendocrine neoplasm (NEN) comprising dual neuroendocrine and non‐neuroendocrine components. Although the coexistence pattern of neuroendocrine and non‐neuroendocrine components in definitive MiNEN is thought to overlap, there may be a coexistent pattern of both components, such as superficial carcinoma adjacent to NEN. The present study evaluated the histopathological findings of the coexistence pattern of superficial carcinomas adjacent to NENs in the esophagogastrointestinal tract.MethodsFrom 2000 to 2019, 35 serial NEN resections of the esophagus (n = 9), stomach (n = 3), and large intestine (n = 23), respectively, were performed at Gunma University Hospital. Borderline areas between NEN and resident superficial epithelium were observed in the 35 serial NEN cases as well as two additional cases from affiliated hospitals.ResultsAmong the 35 serial NEN samples, squamous cell carcinomatous/dysplastic components were identified 77.8% (7/9 cases) of esophageal NENs, and adenocarcinomatous areas were seen in 66.7% (2/3 cases) of gastric NENs and 26% (6/23 cases) of colorectal NENs. Thus, all superficial carcinomatous components adjacent to NENs were observed as squamous cell carcinoma/dysplasia in esophagus and adenocarcinoma in stomach and large intestine, which showed histological characteristics as the resident epithelial pattern in each organ.ConclusionsThese findings suggested a potential “paratransformation” or “bystander effect” in resident epithelium by NENs. Thus, “bystander carcinogenesis” could be a pathogenic mechanism of resident epithelium transformation adjacent to NENs in the esophagogastrointestinal tract.
Severe late‐onset neutropenia induced by ocrelizumab in a multiple sclerosis patient: A case report
Authors: Rauniyar Robin , Rauniyar Rahul , Agrawal Ankita , Yadav Shikha , Avula Sreekant 
Published: January 2022

AbstractOcrelizumab is a recombinant humanized antibody targeted against CD‐20 molecule, which was approved for the treatment of relapsing and primary progressive multiple sclerosis. Common adverse events of ocrelizumab include infusion‐related reactions like rash, pruritus, and flushing. Late‐onset neutropenia (LON) is a rarely reported complication of ocrelizumab therapy. We report a case of severe late‐onset neutropenia in a patient with primary progressive multiple sclerosis treated with ocrelizumab with neutropenia occurring 3 months after the last dose received treated with empirical broad‐spectrum intravenous antibiotics and filgrastim. Severe late‐onset neutropenia is a rare unpredictable adverse event and outlines the importance of regular routine blood workup for detecting severe neutropenia early in its course.
Effects of Channel Hydraulic Diameters and Flow Ratios of Two‐Phase Flow in Y‐Junction Microchannels
Authors: Khan Wasim , Chandra Abhishek K. , Sachan Sadhana , Alam Mohammad Siraj 
Published: January 2022

AbstractThe hydrodynamics of two‐phase flow of a water‐cyclohexane immiscible system with and without obstruction of Y‐junction microchannels under slug flow regime were studied numerically. Flow ratios of water and cyclohexane were varied in a wide range. The results indicate that the slug volume decreases linearly with an increase in flow rate of both fluids; however, the rate of declination in the slug volume for water is higher than that of cyclohexane. For a channel with smaller hydraulic diameter the decrease in slug volume was more pronounced at a constant velocity than that for a channel with a larger hydraulic diameter under identical conditions. The effect of fluid properties along the channel length were compared with existing results.
Affective styles and their association with anxiety and depression in a Japanese clinical sample
Authors: Yamaguchi Keiko , Ito Masaya , Takebayashi Yoshitake , Horikoshi Masaru , Hofmann Stefan G. 
Published: January 2022

AbstractAffective styles are assumed to play an important role in maintaining negative affect, including anxiety and depression. However, little is known about the longitudinal relationship between affective styles and symptoms. Therefore, we conducted a longitudinal study to examine the influence of affective styles, assessed using the Affective Style Questionnaire, on anxiety and depression among clinical populations in Japan. Using an online survey, 1521 participants (406 with major depressive disorder; 479 with one or more anxiety disorders; and 636 with both) answered the Affective Style Questionnaire and measures of emotion regulation, anxiety and depression symptoms. Data were collected twice over 2 months. Confirmatory factor analyses replicated the same four‐factor structure found in a previous sample of Japanese university students. Hierarchical regression analyses revealed that the affective styles had a slightly greater effect on anxiety symptoms but not on depression compared to other common emotion regulation strategies, such as suppression and reappraisal measured by the Emotion Regulation Questionnaire (ERQ). Limitations of this study were that it used online surveys, in which, participants' diagnostic statuses were based on unverifiable self‐reports. In conclusion, the association of affective styles with anxiety and depression among the clinical populations was prospectively confirmed. Further study is needed to examine the association considering the combination or profiles of affective styles among different emotional disorders.
Photochemical Nitrene Transfer Reactions of Iminoiodinanes with Sulfides
Authors: Guo Yujing , Pei Chao , Empel Claire , Jana Sripati , Koenigs Rene M. 
Published: January 2022

AbstractPhotochemical, metal‐free nitrene transfer reactions for C−H amination, aziridination, or sulfilimination are highly desirable. Yet, photochemical sulfilimination reactions of nitrenes with sulfides are underdeveloped as singlet nitrene species would be required for a productive reaction. Herein, we describe the blue‐light‐mediated sulfilimination reaction using iminoiodinanes. We developed a protocol for a highly efficient stoichiometric reaction, which allows for the synthesis of sulfilimines in only 10 minutes reaction time. We further applied our reaction procedure towards allyl sulfides for the synthesis of sulfenamides in a sulfilimination/rearrangement cascade reaction. Moreover, we performed computational calculations and uncovered the participation of a singlet nitrene intermediate, which rapidly reacts with methyl phenyl sulfide to give the desired product.