bluuebunny/crossref_metadata_2025_split huggingface dataset:
Studying leadership: an eclectic approach to qualitative data collection and analysis
Authors: Eftenaru Cristina L. 
Published: October 2022

PurposeThis paper describes the approach to studying leadership within the interpretive paradigm that the author undertook for their doctoral research.Design/methodology/approachFor the study, qualitative data were collected via in-depth interviews and the researcher's systematic reflections. The analytical process consisted of database design and management followed by cyclical interview and cross-interview analyses and integration of the researcher's reflections.FindingsThe paper showed that integrating various qualitative methods in pragmatic ways that better align with the research scope, along with a systematic approach to studying complex phenomena—such as leadership—generated richer and more cohesive perspectives.Research limitations/implicationsThis paper provides a detailed account of how the qualitative data collection and analysis methods were used, which could be replicated or adapted for future research within the interpretive paradigm.Practical implicationsThe paper helps students and junior researchers make sense of qualitative data analysis and interpretation by offering practical tools to tackle the diverse processes of qualitative research.Originality/valueThis paper is based on the Author's doctoral research, recording their experience with engaging in qualitative research.
The Everyday Economy and the Right to Food
Authors: Colás Alejandro , Edwards Jason 
Published: October 2022

AbstractThis article makes the case for incorporating the right to food into notions of the everyday economy in the UK. Beyond the important entitlement to sufficient safe, nutritious and affordable food, the right to food calls for structural change in the current food system and the empowerment of citizens in the everyday production, procurement and consumption of food. We consider the role of reproduction and consumption of food in everyday settings of the household, workplace and community, suggesting that considerations of time combine with questions of earnings and income in addressing the UK's deepening crisis in food security.
Effect of 6‐n‐propyl‐2‐thiouracil or dexamethasone administration on the responses of antimicrobial components in goat milk to intramammary lipopolysaccharide infusion
Authors: Suzuki Naoki , Purba Fika Yuliza , Nii Takahiro , Isobe Naoki 
Published: October 2022

AbstractHeat stress impacts the immune system of dairy animals by altering the hypothalamic–pituitary–adrenal axis and thyroid function, leading to conditions such as hypothyroidism and hypercortisolism. This study aimed to elucidate the effect of hypothyroidism and hypercortisolism on the response of mammary innate immune function to inflammation caused by Escherichia coli in dairy goats. To induce hypothyroidism and hypercortisolism, we administered 6‐n‐propyl‐2‐thiouracil (PTU; for 21 days) and dexamethasone (DEX; for 5 days), respectively, to six goats each; six goats without treatment were used as the control group. After treatment, lipopolysaccharide (LPS) from E. coli O111 was infused into the mammary gland. Somatic cell counts (SCC) and levels of lactoferrin (LF), S100A7, immunoglobulin A (IgA), and interleukin‐8 (IL‐8) in milk until 7 days after LPS infusion were measured. An increase in SCC after LPS infusion was inhibited in both PTU and DEX groups, and an increase in LF after LPS infusion was inhibited in PTU group, compared with that in the control group. The results of the present study suggest that the recruitment of neutrophils and LF production decreased under hypothyroidism or hypercortisolism, which may be one of the causes underlying increased incidence of mastitis in dairy animals under heat stress conditions.
The economics of cryptocurrency: Bitcoin and beyond
Authors: Chiu Jonathan , Koeppl Thorsten V. 
Published: October 2022

AbstractHow well can a cryptocurrency serve as a means of payment? Cryptocurrencies need to overcome double‐spending by costly mining and by delaying settlement. We formalize this insight through an incentive constraint that rules out double‐spending and pins down the welfare costs of a cryptocurrency. We find that it is optimal to use seignorage rather than transaction fees to finance costly mining. In supplementary material, we study an extension with endogenous transaction fees and show quantitatively that the prime cost of Bitcoin arises from mining, but can be reduced substantially by optimally designing the reward system.
Nurses' and medical doctors' attitudes towards exercise for people with chronic kidney disease in Denmark
Authors: Molsted Stig , Bennett Paul N. , Wilund Ken , Bruun Karina , Pakpour Amir H. , Liljehult Jacob Mesot , Brandi Lisbet 
Published: October 2022

AbstractBackgroundImplementation of exercise training in people with kidney failure may be affected by clinicians' attitudes.ObjectivesTo investigate Danish nephrology nurses' and medical doctors' attitudes towards: exercise for people undergoing dialysis; use of physical activity interventions in chronic kidney disease; and to compare Danish and previously reported Australian nurse attitudes.DesignCross‐sectional survey.ParticipantsNurses and medical doctors from the nephrology field in Denmark.MeasurementsThe questionnaire attitudes towards exercise in dialysis, and questions about exercise advice, counselling and interventions.ResultsNephrology nurses (n = 167) and 17 medical doctors (women 92%, age 47 ± 11 years) from 19 dialysis units participated. There were no differences between nurses' and medical doctors attitudes about training. Ninety‐five % and 88% of nurses and medical doctors, respectively, agreed that most people undergoing dialysis could benefit from exercise. Exercise training was offered to people undergoing haemodialyses in 88% of 17 departments. Danish nurses reported more positive attitudes than Australian towards exercise (p < 0.05). Ninety‐five % and 86% of the Danish and Australian nurses, respectively, agreed/strongly agreed that most people undergoing dialysis could benefit from exercise. Six % and 35% of the Danish and Australian nurses, respectively, agreed/strongly agreed that most people with dialysis were too sick to exercise.ConclusionDanish nephrology nurses and medical doctors had mostly positive attitudes to exercise training to people undergoing dialysis, and exercise to people with dialysis was offered frequently. Danish and Australian nurses had positive attitudes to exercise to people undergoing dialysis, it was however more positive in Danish nurses.
The joint macroeconomic impacts of capital markets integration and fertility
Authors: Davoine Thomas 
Published: October 2022

AbstractPopulation aging puts pressure on the financing of pension systems in many developed economies over the long run. Higher fertility would reduce the speed at which a population ages, and thus ease the financing pressure. The positive fiscal externality of childbearing decisions is well known in a single‐country context. I perform a quantitative investigation of this externality in a multi‐country context, to investigate the role of capital markets integration. On a sample of 14 European countries confronted with population aging, I find with simulations that the fiscal gains from a 70‐years increase in fertility are on average 1.3 larger with integrated capital markets than with separated capital markets in 50 years, while the GDP per capita gains are 5.0 larger. Positive fertility shocks indeed depress the capital‐labor ratio, increase the interest rate and thus attract foreign investors, when capital markets are open. Fertility increases and capital markets integration are however not sufficient to deal fully with the public finance challenge generated by population aging. More reforms are needed.
Use of information and communication technologies (ICTs) in cancer multidisciplinary team meetings: an explorative study based on EU healthcare professionals
Authors: Prades Joan , Coll-Ortega Cristina , Dal Lago Lissandra , Goffin Karolien , Javor Eugen , Lombardo Claudio , de Munter Johan , Ponce Jordi , Regge Daniele , Salazar Ramón , Valentini Vincenzo , Borras Josep M 
Published: October 2022

ObjectivesMultidisciplinary teams in cancer care are increasingly using information and communication technology (ICT), hospital health information system (HIS) functionalities and ICT-driven care components. We aimed to explore the use of these tools in multidisciplinary team meetings (MTMs) and to identify the critical challenges posed by their adoption based on the perspective of professionals representatives from European scientific societies.DesignThis qualitative study used discussion of cases and focus group technique to generate data. Thematic analysis was applied.SettingHealthcare professionals working in a multidisciplinary cancer care environment.ParticipantsSelection of informants was carried out by European scientific societies in accordance with professionals’ degree of experience in adopting the implementation of ICT and from different health systems.ResultsProfessionals representatives of 9 European scientific societies were involved. Up to 10 ICTs, HIS functionalities and care components are embedded in the informational and decision-making processes along three stages of MTMs. ICTs play a key role in opening MTMs to other institutions (eg, by means of molecular tumour boards) and information types (eg, patient-reported outcome measures), and in contributing to the internal efficiency of teams. While ICTs and care components have their own challenges, the information technology context is characterised by the massive generation of unstructured data, the lack of interoperability between systems from different hospitals and HIS that are conceived to store and classify information rather than to work with it.ConclusionsThe emergence of an MTM model that is better integrated in the wider health system context and incorporates inputs from patients and support systems make traditional meetings more dynamic and interconnected. Although these changes signal a second transition in the development process of multidisciplinary teams, they occur in a context marked by clear gaps between the information and management needs of MTMs and the adequacy of current HIS.
Role of COVID-19 pandemic in the academic life and well-being of private sector university students: an exploratory qualitative study
Authors: Ali Naureen Akber , Feroz Anam Shahil , Akber Noshaba , Khoja Adeel 
Published: October 2022

ObjectiveThe advent of the COVID-19 pandemic has caused a drastic impact on students’ life, causing physical and emotional sufferings. Considering the relevance of unprecedented conditions, we explored perceptions and attitudes of students towards their academic life and well-being amid the COVID-19 pandemic.SettingWe conducted an exploratory qualitative study using a purposive sampling approach conducted at a single-centre private nursing institution in Karachi, Pakistan.ParticipantsThe current study used in-depth interviews with female university students. Study data were analysed manually using the thematic analysis approach.Primary outcomeThe primary outcome is to explore perception of students on academic life and well-being amidst the COVID-19 pandemic.ResultsA total of 10 in-depth interviews were conducted between August and September 2020. Four overarching themes were identified: (1) impact of COVID-19 on students’ well-being; (2) effect of COVID-19 on students’ academic life; (3) current coping mechanisms adopted by students and (4) recommendations to address students’ concerns. The pandemic-related stressors served as a major impediment on students’ motivation, concentration span and socioeconomic conditions which negatively influenced their well-being and academic life. However, students have adopted diverse coping mechanisms to combat unstable circumstances that include connecting with family and relatives, indulging in diverse activities, and getting academic support from faculty, senior students, and university administration. Students also recommended the need for arranging online mental health services, integrating e-learning mediums in existing academia, and constant efforts by the government to address electricity and internet connectivity issues to promote virtual learning.ConclusionUniversity students have been struck hard due to rapid pandemic-related transitions in their life. The study finding served as the potential guide for educational institutions and government officials to employ appropriate psychological interventions and provide infrastructure and technical facilities to provide support with their academic journey and overcoming the ongoing pandemic repercussions.
Primary Care Severe Asthma Registry and Education Project (PCSAR-EDU): Phase 1 – an e-Delphi for registry definitions and indices of clinician behaviour
Authors: D'Urzo Katrina A , Tamari Itamar E , Chapman Kenneth R , Maleki-Yazdi M Reza , Greiver Michelle , Upshur Ross EG , Biro Lana , O'Neill Braden , Moineddin Rahim , Aliarzadeh Babak , Kulasegaram Kulamakan , To Teresa , D'Urzo Anthony D 
Published: October 2022

IntroductionAlthough most asthma is mild to moderate, severe asthma accounts for disproportionate personal and societal costs. Poor co-ordination of care between primary care and specialist settings is recognised as a barrier to achieving optimal outcomes. The Primary Care Severe Asthma Registry and Education (PCSAR-EDU) project aims to address these gaps through the interdisciplinary development and evaluation of both a ‘real-world’ severe asthma registry and an educational programme for primary care providers. This manuscript describes phase 1 of PCSAR-EDU which involves establishing interdisciplinary consensus on criteria for the: (1) definition of severe asthma; (2) generation of a severe asthma registry and (3) definition of an electronic-medical record data-based Clinician Behaviour Index (CBI).Methods and analysisIn phase 1, a modified e-Delphi activity will be conducted. Delphi panellists (n≥13) will be invited to complete a 30 min online survey on three separate occasions (i.e., three separate e-Delphi ‘rounds’) over a 3-month period. Expert opinion will be collected via an open-ended survey (‘Open’ round 1) and 5-point Likert scale and ranking surveys (‘Closed’ round 2 and 3). A fourth and final Delphi round will occur via synchronous meeting, whereby panellists approve a finalised ideal ‘core criteria list’, CBI and corresponding item weighting.Ethics and disseminationEthical approval has been obtained for the activities involved in phase 1 from the University of Toronto’s Human Research Ethics Programme (approval number 39695). Future ethics approvals will depend on information gathered in the proceeding phase; thus, ethical approval for phase 2 and 3 of this study will be sought sequentially. Findings will be disseminated through conference presentations, peer-reviewed publications and knowledge translation tools.
Collaborative research methods and best practice with children and young people: protocol for a mixed-method review of the health and social sciences literature
Authors: Nowland Rebecca , Robertson Laura , Farrelly Nicola , Roy Alastair , Sharpe Darren , Harris Cath , Morocza Nora , Larkins Cath 
Published: October 2022

IntroductionChildren and young people have the right to participate in research on matters that affect them, and their contribution improves research quality and insights from findings. Discrete participatory approaches are used across different disciplines. This review will provide a synthesis of existing literature from different disciplines by working with young people and adults experienced in participatory research to develop a broad definition of child and youth led research and to identify best practice.Methods and analysisComprehensive searches will be conducted in eight electronic databases (PsycINFO, Medline, CINAHL, Embase, SocINDEX, ASSIA: Applied Social Sciences Index and Abstracts (Proquest), Social Care Online and SCOPUS). Grey literature reports will also be sourced using Google searching. Eligible studies will be English-language primary studies and reviews on collaborative research with children and young people (aged 5–25 years) published from 2000 onwards. Qualitative and quantitative data will be integrated in a single qualitative synthesis following the JBI convergent integrated approach. Study quality will be assessed by developed checklists based on existing participation tools cocreated with the project steering group and co-creation activities with young people.Ethics and disseminationEthical approval is not required as no primary data will be collected. The review will develop guidance on best practice for collaborative research with children and young people, synthesising learnings from a wide variety of disciplines. Dissemination will be via peer-reviewed publications, presentations at academic conferences and lay summaries for various stakeholders. Opportunities for cocreation of outputs will be sought with the young researchers and the project steering committee.PROSPERO registration numberCRD42021246378.
Durable response of anaplastic thyroid carcinoma to FS118, a bispecific LAG-3/PD-L1 antibody, after checkpoint inhibitor progression: a case report
Authors: Kroloff Maxwell J , Holz Josefin-Beate , Stern Omer , Shepherd Christopher J , Morrow Michelle , Kayitalire Louis , Wong Deborah J 
Published: October 2022

Anaplastic thyroid cancer represents a rare, highly aggressive form of thyroid cancer with a poor prognosis and an overall survival ranging from 5 to 12 months. Unfortunately, treatment options remain limited, even for patients with a targetable driver mutation. Here, we present a case of a patient with a BRAF V600E-mutated, PD-L1 positive (tumor proportion score of 95%) anaplastic thyroid cancer refractory to standard therapies, including debulking surgery, followed by chemoradiation, who had further progressed on PD-1 monotherapy, and was unable to tolerate BRAF/MEK inhibition. Ongoing treatment with FS118, a bispecific LAG-3/PD-L1 antagonist, has afforded 3 years of disease control, including a late confirmed partial response, with excellent tolerability. Given this response, further investigation is required to delineate the mechanism by which dual PD-L1/LAG-3 blockade by FS118 overcomes initial PD-1 pathway resistance, and therefore, identify which patients are most likely to benefit. Simultaneously, expanded use should be considered for those with refractory disease, especially if PD-L1 positive.InsightsDual PD-L1/LAG-3 blockade may be an effective treatment strategy for refractory metastatic tumors, including anaplastic thyroid cancer.
ER-851, a Novel Selective Inhibitor of AXL, Overcomes Resistance to Antimitotic Drugs
Authors: Tsukamoto Shuntaro , Sugi Naoko Hata , Nishibata Kyoko , Nakazawa Youya , Ito Daisuke , Fukushima Sayo , Nakagawa Takayuki , Ichikawa Kenji , Kato Yu , Kakiuchi Dai , Goto Aya , Itoh-Yagi Machiko , Aota Tomoki , Inoue Satoshi , Yamane Yoshinobu , Murai Norio , Azuma Hiroshi , Nagao Satoshi , Sasai Ken , Akagi Tsuyoshi , Imai Toshio , Matsui Junji , Matsushima Tomohiro 
Published: October 2022

Abstract
Innate and adaptive resistance to cancer therapies, such as chemotherapies, molecularly targeted therapies, and immune-modulating therapies, is a major issue in clinical practice. Subpopulations of tumor cells expressing the receptor tyrosine kinase AXL become enriched after treatment with antimitotic drugs, causing tumor relapse. Elevated AXL expression is closely associated with drug resistance in clinical samples, suggesting that AXL plays a pivotal role in drug resistance. Although several molecules with AXL inhibitory activity have been developed, none have sufficient activity and selectivity to be clinically effective when administered in combination with a cancer therapy. Here, we report a novel small molecule, ER-851, which is a potent and highly selective AXL inhibitor. To investigate resistance mechanisms and identify driving molecules, we conducted a comprehensive gene expression analysis of chemoresistant tumor cells in mouse xenograft models of genetically engineered human lung cancer and human triple-negative breast cancer. Consistent with the effect of AXL knockdown, cotreatment of ER-851 and antimitotic drugs produced an antitumor effect and prolonged relapse-free survival in the mouse xenograft model of human triple-negative breast cancer. Importantly, when orally administered to BALB/c mice, this compound did not induce retinal toxicity, a known side effect of chronic MER inhibition. Together, these data strongly suggest that AXL is a therapeutic target for overcoming drug resistance and that ER-851 is a promising candidate therapeutic agent for use against AXL-expressing antimitotic-resistant tumors.
Cosmopolitical Spiritualities of Deep Time
Authors: Kotva Simone 
Published: October 2022

Abstract
This article considers J. G. Ballard’s account of deep time in The Drowned World (1962) from a religious perspective. I situate Ballard’s account of deep time in the context of Mircea Eliade’s influential work on the “Real Time” of ecstasy—a time in which humans recognize their indistinctness from the animal and undergo an experience of self-annihilation. But Eliade’s is not the only interpretation of ecstatic temporality that is relevant to Drowned World. I argue that Ballard also narrates a constructive response to deep time that issues not in self-annihilation but in communal action and group living. It is in order to parse this aspect of Ballard’s account of deep time that I turn, in the final part of the article, to consider Drowned World as an anticipation also of more recent, cosmopolitical approaches to ecstatic temporalities by theologians, anthropologists and philosophers.
A female mimic signal type in the vibrational repertoire of male Enchenopa treehoppers
Authors: Escalante Ignacio , Kellner Jerald R. , Rodríguez Rafael L. , Desjonquères Camille 
Published: October 2022

Abstract
Animals vary in the complexity and size of the signal repertoire used in communication. Often, these behavioural repertoires include multiple signal types for the same process, for instance, courtship. In Enchenopa treehoppers (Hemiptera: Membracidae) mate-searching males produce plant-borne vibrational advertisement signals. Receptive females then respond to males with their own signals. Here we describe an additional signal type in the repertoire of these males. We collected nymphs in Wisconsin, USA, and recorded the spontaneous signalling bouts of adult males and duetting signals of females using laser vibrometry. Two-thirds of males produced the additional signal type, which differed in temporal and spectral features from the main male advertisement signals, whilst resembling female duetting signals in placement and acoustic features. Our findings suggest that this might be a female mimic signal. Overall, our findings highlight the diversity in the behavioural repertoire that animals may use for reproduction.
Gibt es eine österreichische Psychologie?
Authors: Antonelli Mauro 
Published: October 2022

Abstract
This article, inspired by Rudolf Haller’s thesis of an independent, specific, and unitary Austrian tradition of scientific philosophy, develops the idea of a specific Austrian tradition of psychological research, as distinguished in its development from that in Germany. This tradition was shaped by two phenomenological trends, which were merged into unity in Prague by Carl Stumpf and Brentano’s students of the second generation. One trend traces back to Goethe and was continued in Prague by the physiologists Jan E. Purkinje and Ewald Hering, culminating in the work of Ernst Mach. The other trend was initiated by Franz Brentano and spread through his school. Stumpf was the key integrator of these two traditions, which he then partially passed on to his Berlin students and founders of Gestalt psychology. Finally, Karl Bühler’s “reimport” of the Brentanian psychological legacy into the Vienna of the First Republic is briefly illustrated.