bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fiber Glass/Kenaf Reinforced Thermoset Composite with Microcrystalline Cellulose as Filler in a Different Fluid Immersion
Authors: Palmiyanto Martinus Heru , Surojo Eko , Ariawan Dody , Imaduddin Fitrian 
Published: August 2022

Abstract
Microcrystalline cellulose (MCC) is one of the good and environmentally friendly natural rigid fillers used in polymer matrix composites to improve mechanical properties. However, the reliability of this MCC composite cannot be ensured in a humid environment or submerged in water with different pH. This study investigated the addition of MCC filler to the absorption of distilled water (pH 7), seawater (pH8), and acid solution (pH 3), flexural strength, and flexural modulus of kenaf/glass fiber reinforced polymer composites. Soaking the composite for 60 days in distilled water and seawater showed an increase in the concentration of water absorption. Water absorption by the kenaf fibers causes the fibers to swell and provides an expansion to the matrix resulting in crack propagation and the growth of new cracks in the matrix. The behavior of the composite in an acidic solution shows a mass loss, and the matrix erodes on the surface and inside the material. The flexural strength and flexural modulus of the composite decreased at all immersions. The addition of MCC as a reinforcing filler for thermoset composites increases the interfacial interaction between the matrix and the kenaf/glass fiber. The improved mechanical properties of MCC-filled composites in different pH environments create opportunities and reliability for use in different engineering applications.
Two-step flotation and reverse flotation circuits of iron oxide and its process minerology
Authors: Hou Ying , Lin Song , Fu Guohui , Gai Zhuang , Yang Guang , Sobhy Ahmed 
Published: August 2022

Abstract
Mining operations usually provide ore of varying characteristics. Similarly, for Donganshan Sintering Plant, the charges in iron oxide ore especially prior flotation process were investigated by conducting mineral liberation analyzer “MLA”. This in-deep study of process mineralogy explored and analyzed the mechanism of difficulty to obtain high-efficient flotation process. The MLA analysis results showed also that the main useful minerals in this ore are magnetite/hematite, and the main gangue minerals is quartz, followed by chlorite and ankerite. In addition, two-step “direct then reverse” and one step “reverse” flotation experiments were carried out and produced iron oxide concentrates of 48.91% and 49.45% yield; 65.03% and 65.22% grade; 70.96% and 72.08% recovery respectively. Besides, the process flow sheet was simplified with reduced reagent consumptions.
Low Degree / High Degree polynomial decomposition in a large population of healthy normal eyes and how it compares to the Zernike polynomials: an observational study
Authors: Karcenty Mickael , Barugel Raphael , Karcenty John-Evan , Debellemanière Guillaume , Rampat Radhika , Mazharian Adrien , Malet Jacques , Dumas Laurent , Gatinel Damien 
Published: August 2022

Abstract

Purpose: To evaluate and compare the ocular aberrations in healthy normal eyes with Zernike versus Low Degree/High Degree (LD/HD) coefficients using OPD-Scan III wavefront sampling.Methods: Retrospective case series. Ocular wavefront acquisition using automated skiascopy was performed in mesopic conditions on refractive surgery candidates. Root Mean Square (RMS) values were computed for 6 mm pupils and aberration data from the 1st to the 6th order were exported.A Principal Component Analysis was performed to investigate which of the two classifications explained better the variance of the wave aberrations for their respective higher order wavefront components.Results: Data from 3827 eyes of 2110 patients were analyzed. Z1-1 (horizontal tilt) and Z11 (vertical tilt) modes had a mean absolute RMS of 0.299 +/- 0.233 μm and 0.242 +/- 0.194 μm. G1-1 and G11 had a mean absolute RMS of 0.051 +/- 0.044 μm and 0.045 +/- 0.039 μm. Total Zernike coma (Z3-1, Z31, Z5-1 and Z51) had a mean absolute RMS of 0.168 +/- 0.089 μm. Total LD/HD coma (G3-1, G31, G5-1 and G51) had a mean absolute RMS of 0.488 +/- 0.261 μm. Zernike Spherical Aberration (SA = Z40) had a mean absolute RMS of 0.093 +/- 0.070 μm while LD/HD SA (Z40) had a mean absolute RMS of 0.642 +/- 0.481 μm. PCA demonstrated that the LD/HD classification provided a new set of basis functions that better fitted the variance of HOAs, compared with the Zernike classification.Conclusion: This study standardizes Zernike and LD/HD based wavefront reconstructions using the OPD-Scan III in mesopic conditions. LD/HD classifications appear to offer a more efficient description of the eye’s aberrations. The main differences of both classifications are expanded upon.
Hsa_circ_0008344 promotes glioma cells proliferation, invasion and migration via miR-556- 5p/NLRP3/NF-κB signaling pathway
Authors: Xue LiPing , Lu Bin , CaiQi Jiang , Sun Ke , He QiBin , Jiang Hao , Ding Peng 
Published: August 2022

Abstract
The circular RNAs (circRNA) are becoming more important in cancer development. However, the functional role of circRNA in glioblastoma is still remain to be deeply studied. In the current study, we used CCK-8, flow cytometry, transwell, western blot, and RT-PCR assays to determine the expression of has_circ_0008344 in different glioma cells. Results showed that the expression level of hsa_circ_0008344 in glioma cells was remarkably higher than normal HCGC cells. Down-regulation of hsa_circ_0008344 significantly decreased the proliferation rate, increased apoptotic rate, impaired invasion and migration capacity in U87MG and U251MGA cells. We found that miR-513a-5p mimics could significantly reverse the over-expression of hsa_circ_0008344 and enhancing the knocking-down of hsa_circ_0008344. Moreover, NLRP3 promoted the biological activities of glioma cells coordinately with hsa_circ_0008344 and could reverse the impact of miR-513a-5p mimics on over-expression of hsa_circ_0008344 treated glioma cells. Also activated p-NF-κB involved in the invasion and migration of glioma cells. In conclusion, the present study demonstrates that hsa_circ_0008344 is up-regulated in glioma in vitro and promoted the proliferation activity, invasion and migration of glioma cells by ameliorating miR-556-5p/NLRP3/NF-κB signaling pathway. Our results may contribute to the diagnosis and treatment of glioma in the future.
TRβ gene expression of Sprague- Dawley rats’ hypothyroidism treated with non-Protein amino acid beta-amino butyric acid (βABA)
Authors: Mohammed Saja Aied , Jasim Mohammed Abbas 
Published: August 2022

Abstract
Thyroid receptors TRα, TRβ, and other receptor subunits belong to the nuclear receptor family as they mediate thyroid hormone signaling to regulate a wide range of physiological processes including growth and metabolism. Our study aimed to investigate the effect of beta-aminobutyric acid (βABA) on the gene expression of the TRβ gene in 30 male Sprague-Dawley rats with hypothyroidism and normal condition. Animals were divided into six groups, three of which developed hypothyroidism by intraperitoneal injection with propylthiouracil (PTU) daily for 15 days, while the other three groups did not develop hypothyroidism and remained healthy. Then four groups of rats (two infected and two normal groups) were injected with two concentrations of (βABA) (100 and 200 mg/kg body weight) three times a week for two weeks. An infected control group was left for βABA treated groups and a normal control group was left for all groups. The gene expression level of the TRβ gene was measured, and it was found that there was a decrease in relation to the infected control group only while the expression value increased in the infected and treated groups treated with amino acid in both concentrations and with regard to the normal and injected groups with (βABA), the gene expression increased in the group injected with a concentration of 100 mg/kg only. We conclude that BABA had a positive role in regulating the secretion of pro-and anti-inflammatory cytokines under studied concentrations besides it had a positive role in increasing the expression of the TRβ gene.
Stoma Versus Anastomosis After Sphincter-Sparing Rectal Cancer Resection; the Impact on Health-Related Quality of Life
Authors: Algie Jelle P.A. , Kooten Robert T. , Tollenaar Rob A.E.M. , Wouters Michel W.J.M. , Peeters Koen C.M.J. , Dekker Jan Willem T. 
Published: August 2022

Abstract
Background
Surgical resection is the mainstay of curative treatment for rectal cancer. Post-operative complications, low anterior resection syndrome (LARS) and the presence of a stoma may influence the quality of life after surgery. This study aimed to gain more insights into the long-term trade-off between stoma and anastomosis.
Methods
All patients who underwent sphincter-sparing surgical resection for rectal cancer in the Leiden University Medical Center and the Reinier de Graaf Gasthuis between January 2012 and January 2016 were included. Patients received the following questionnaires: EORTC-QLQ-CR29, EORTC-QLQ-C30, EQ-5D-5L and the LARS-score. A comparison was made between patients with a stoma and without a stoma after follow-up.
Results
Some 210 patients were included of which 149 returned the questionnaires (70.9%), after a mean follow-up of 3.69 years. Overall quality of life was not significantly different in patients with and without stoma after follow-up using the EORTC-QLQ-C30 (p = 0.15) or EQ-5D-5L (p = 0.28). However, after multivariate analysis, a significant difference was found for the presence of a stoma on global health status (p = 0.01) and physical functioning (p < 0.01). Additionally, there was no difference detected in the quality of life between patients with major-LARS or a stoma.
Conclusion
This study shows that, after correction for possible confounders, a stoma is associated with lower global health status and physical functioning. However, no differences were found in health-related quality of life between patients with major-LARS and patients with a stoma. This suggests that the choice between stoma and anastomosis is mainly preferential, and that shared decision-making is required.
Benefit-sharing in International Law Post-2020 Global Biodiversity Framework and reciprocity
Authors: Sirakaya Aysegül 
Published: August 2022

Abstract
Benefit-sharing is a twofold concept that appears both in the realm of human rights law and environmental law. This is because the achievement of many human rights objectives such as those listed under the UN Sustainable Development Goals inherently depends on the maintenance of a healthy environment (A/HRC/19/34, A/RES/70/1). The lack of achievement related to environmental objectives can therefore jeopardize the achievement of human rights objectives. The Special Rapporteur on the issue of human rights obligations relating to the enjoyment of a safe, clean, healthy, and sustainable environment states that the “enormous problem is that [biodiversity agreements] have often not been effectively implemented and their goals have not been met.” (A/HRC/31/52) Consequently, the provenance and prevalence of benefit-sharing in international law need analysis from both the human rights and the environmental law perspectives as they are interdependent. This paper initiates a holistic study on benefit-sharing in international law by exploring its application in the Global Biodiversity Framework through interconnected principles of human rights and environmental law, theory of change, rights-based-approach, and intergenerational equity.
Detection of Changes in the Dynamics of Thermonuclear Plasmas to Improve the Prediction of Disruptions
Authors: CRACIUNESCU Teddy , Murari Andrea 
Published: August 2022

Abstract
In particular circumstances, nonlinear systems can collapse suddenly and abruptly. Anomalous detection is therefore an important task. Unfortunately, many phenomena occurring in complex systems out of equilibrium, such as disruptions in tokamak thermonuclear plasmas, cannot be modelled from first principles in real time compatible form and therefore data driven, machine learning techniques are often deployed. A typical issue, for training these tools, is the choice of the most adequate examples. Determining the intervals, in which the anomalous behaviours manifest themselves, is consequently a challenging but essential objective. In this paper a series of methods are deployed to determine when the plasma dynamics of the tokamak configuration varies, indicating the onset of drifts towards a form of collapse called disruption. The techniques rely on changes in various quantities derived from the time series of the main signals: from the embedding dimensions to the properties of recurrence plots and to indicators of transition to chaotic dynamics. The methods, being mathematically completely independent, provide quite robust indications about the intervals, in which the various signals manifest a predisruptive behaviour. Consequently, the signal samples, to be used for supervised machine learning predictors, can be defined precisely, on the basis of the plasma dynamics. This information can improve significantly not only the performance of machine learning classifiers but also the physical understanding of the phenomenon.
An NLP-Assisted Bayesian Time Series Analysis for Prevalence of Twitter Cyberbullying During the COVID-19 Pandemic
Authors: Perez Christopher , Karmakar Sayar 
Published: August 2022

Abstract
COVID-19 has brought about many changes in social dynamics. Stay-at-home orders and disruptions in school teaching can influence bullying behavior in-person and online, both of which leading to negative outcomes in victims. To study cyberbullying specifically, 1 million tweets containing keywords associated with abuse were collected from the beginning of 2019 to the end of 2021 with the Twitter API search endpoint. A natural language processing model pre-trained on a Twitter corpus generated probabilities for the tweets being offensive and hateful. To overcome limitations of sampling, data was also collected using the count endpoint. The fraction of tweets from a given daily sample marked as abusive is multiplied to the number reported by the count endpoint. Once these adjusted counts are assembled, a Bayesian autoregressive Poisson model allows one to study the mean trend and lag functions of the data and how they vary over time. The results reveal strong weekly and yearly seasonality in hateful speech but with slight differences across years that may be attributed to COVID-19.
Impact of age on the cerebrospinal fluid spaces: high-convexity and medial subarachnoid spaces decrease with age
Authors: Hidaka Yosuke , Hashimoto Mamoru , Suehiro Takashi , Fukuhara Ryuji , Ishikawa Tomohisa , Tsunoda Naoko , Koyama Asuka , Honda Kazuki , Miyagawa Yusuke , Yoshiura Kazuhiro , Boku Shuken , Ishii Kazunari , Ikeda Manabu , Takebayashi Minoru 
Published: August 2022

Abstract
Background: Impaired cerebrospinal fluid (CSF) dynamics may contribute to the pathophysiology of neurodegenerative diseases. CSF dynamics may play a crucial role in brain health in older people; nonetheless, such age-related changes have not been well elucidated. Disproportionately enlarged subarachnoid-space hydrocephalus (DESH) is a neuroimaging phenotype of idiopathic normal-pressure hydrocephalus, which originates from impaired CSF dynamics. DESH is closely associated with aging; therefore, this study aimed to investigate the pathophysiology of DESH and determine age-related changes in CSF dynamics.Methods: Using magnetic resonance imaging, we investigated the pathophysiology of DESH by quantitatively evaluating the volumes of DESH-related regions (ventricles [VS], Sylvian fissure [SF], and subarachnoid spaces at high convexity and midline [SHM]) and brain parenchyma in community-dwelling individuals aged ≥65 years. DESH-related regions were assessed using a visual rating scale, and their volumes were measured using voxel-based morphometry. The brain parenchyma volumes were measured using FreeSurfer software.Results: The data of 1,356 individuals were analyzed, and 25 (1.8%) individuals had DESH. Regarding the relationships between the volume of each CSF space and age, VS and SF volumes increased with age, whereas SHM volume decreased with age. The VS and SF volumes increased as the whole brain volume decreased, whereas SHM volume decreased as the whole brain volume decreased; that is, SHM narrowed as brain atrophy progressed. Moreover, lower Mini-Mental State Examination scores were significantly associated with lower SHM volume and higher VS volume. These associations remained significant even when individuals with DESH were excluded.Conclusions: This study showed that the volume of high-convexity and medial subarachnoid spaces decreases with age; the human brain continuously progresses toward a “DESH-like” morphology with aging in community-dwelling older persons (i.e., DESH is an “accelerated aging stage” but not an “age-related disorder”). Our results indicated that brain atrophy is associated with the development of “DESH-like” morphology. In addition, this morphological change, as well as brain atrophy, is an important condition that can cause cognitive decline in older adults. Our findings highlight the importance of investigating the aging process of CSF dynamics in the human brain to preserve brain health in older people.
Limnobacter parvuscolonica sp. nov., thiosulfate-oxidizing bacterium isolated from lake water
Authors: Xamxidin Maripat , Huang Xin-Peng , Yang Xiang-Wei , Wang Tao , Chen Can , Wu Min 
Published: August 2022

Abstract
A novel bacterium, strain YS8-69T, was isolated from an inland closed lake, Xinjiang province, PR China. Comparative analysis of the 16S rRNA gene sequence shows the strain is affiliated to the genus Limnobacter, in the family Burkholderiaceae, with the highest similarities to Limnobacter alexandrii LZ-4T (98.93%), Limnobacter thiooxidans DSM 13612T (98.55%), Limnobacter humi NBRC 111650T (97.66%), and Limnobacter litoralis KP1-19T (97.04%). Strain YS8-69T was a Gram-stain-negative, rod-shaped, catalase- and oxidase-positive bacterium, and growth was observed at 4–40°C (optimum, 25°C), pH 7.0–10.0 (optimum, pH 7.0) and 0–3% (w/v) NaCl (optimum, 0.5%). It grew chemolithoautotrophically using thiosulfate. The principal fatty acids were C16:0, summed feature 3 (C16:1 ω7c and/or C16:1 ω6c), and summed feature 8 (C18:1 ω7c and/or C18:1 ω6c). The major respiratory quinone was Q-8 and predominant polar lipids were diphosphatidylglycerol (DPG), phosphatidylglycerol (PG), phosphatidylethanolamine (PE), two unidentified aminolipids (AL1,2), two unidentified glycolipids (GL1,2), an unidentified amino phosphoglycolipid (APGL), two unidentifed phospholipid (PL1,2), and two unidentified lipids (L1,2). The average nucleotide identity (ANI) values between strain YS8-69T and L. thiooxidans JCM 13612T, L. humi DSM 111650T were 36% and 15.80% respectively. The final genome sequencing showed that length of strain YS8-69T genome was 3,162,663 bp, with 20 contigs, and 51.7 mol % of G + C content. Based on physiological, chemotaxonomic, genotypic characteristics, and phylogenetic results in the polyphasic taxonomy approach, we propose that strain YS8-69T represents a novel specie of the genus Limnobacter, for which the name Limnobacter parvuscolonica sp. nov. is proposed (type strain YS8-69T = MCCC 1K08015T = KCTC 92278T).
Using minimax techniques for nonlinear programming with many inequality constraints
Authors: Jiang Xiaowei , Yang Yueting , Cao Mingyuan , Zhou Guoling 
Published: August 2022

Abstract
In this paper, the inequality constrained optimization problem is transformed into a minimax problem. The objective function of the latter is essentially an exact penalty function, which can avoid the appearance of the ill-conditioning case when the penalty parameter is too large. For the max-value function containing 0 in minimax problem, most of the previous literatures approximate max{0, f i (x)}(i = 1, 2, · · · , m) one by one, while a modified flattened aggregate function proposed in this paper can approximate max{0, f 1 (x), · · · , f m (x)} in whole, which brings great convenience to solve the optimization problems with many constraints. By carefully updating aggregate parameters, the smooth unconstrained optimization problem is solved by a conjugate gradient method, which can usually save much computation of gradients and Hessians of constraint functions. Convergence of the proposed method is proven. A numerical procedure is given to implement the proposed method, and preliminary computational results show its efficiency.
A study on some physical and mechanical properties of molded thermal insulation materials produced from perlite and boric acid added forestry by-products
Authors: Efe Fatih Tuncay 
Published: August 2022

Abstract
Thousands of tons of bark and cones are produced each year in the forest products industry and the natural life cycle of forests. These raw materials are either burned or left in the forest. In both cases, it causes both environmental problems and a significant loss of economic potential. On the other hand, the demand for thermal insulation materials is increasing day by day, and more synthetic and fossil-based raw materials with negative environmental effects are consumed. In this study, some physical and mechanical properties of molded thermal insulation materials produced from natural raw materials were investigated experimentally. In this context, 15 types of sandwich panel materials containing honeycomb-shaped core were produced from pine (Pinus brutia Ten.) bark and cones. The mean moisture content, density, compressive strength, tensile strength perpendicular to the surface (Internal adhesion strength), tensile strength parallel to the surface (Tensile strength), and dimensional stability (width-length-thickness change) values of the materials were 10.600%, 269.717 kg/m3, 0.493.06 N/mm2, 0.011 N/mm2, 0.150 N/mm2 and − 0.156%, -0.054%, 0.942%, respectively. According to the results, it was determined that the increase in particle size and perlite ratio in the materials produced from the bark decreased the density. Moreover, it was found that the particle size-moisture content relationship and the perlite ratio-moisture content relationship varied in the materials containing bark and cones, that the mechanical properties were higher in the materials containing cones, and that the dimensional stability did not show a regular change.
Unmanned Aerial Vehicle assisted Intelligent approach to Manage the Resources for Defense Systems
Authors: Biswas Tarun , Anirudh Pokala , Raj Ayush , Rupesh Galla , Ray Anjan Kumar 
Published: August 2022

Abstract
Generally, resources are transported through manned transportation in a distant war zones. The manual transportation of the resources involve various constrains such as time consuming, risk, cost. Efficient management of these limited resources is one of the primary desiring factors to decide the fate of war. Compu-tationally, resource management is an non-deterministic polynomial hard (NP-hard) problem. In this work, several novel resources management algorithms are designed for defence systems by utilization the intelligence of UAV and Jaccard coefficient and Overlap coefficient mathematical support. The intelligent use of Unmanned Aerial Vehicles (UAVs) facilitate resources management in faster, less risky and efficient manner. The proposed UAV assisted resource management algorithms are analyzed and validated over various synthetic simulated war going situations data sets. The proposed algorithms show significant performance in the total service time, utilization of deployed UAVs and number of flights.