bluuebunny/crossref_metadata_2025_split huggingface dataset:
LyBERT: Multi-class classification of lyrics using Bidirectional Encoder Representations from Transformers (BERT)
Authors: Rajendran Revathy V , Pillai Anitha S , Daneshfar Fatemah 
Published: April 2022

Abstract
Recent developments in music streaming applications and websites have made the music emotion recognition task continually active and exciting. Recognizing the music mood has many advantages. One of them is that it helps find out the prominent feeling or state of mind it brings to a listener. Identifying a listener's taste is the primary motive of currently available music emotion recognition systems such as music streaming systems (YouTube), music recommender systems (Spotify), automatic playlist generation, etc. Being a subdomain of music information retrieval (MIR), for the past years, several challenges of music emotion recognition have been studied and solved by researchers. Music emotion recognition's significant challenges include data accessibility, data volume, recognizing emotionally relevant features, etc. Several researchers have proved that emotionally relevant features can be identified by analyzing multiple features and the semantic features of lyrics and effects of audio signals create music emotion. Then one can initiate the music recognition task from a lyrical perspective because it has semantic features and audio features such as valence and arousal. The challenging part is the availability of these features that influence the music's emotion.
The lyrical features relevant for identifying four emotions (happy, sad, relaxed, and angry) were learned with the help of state-of-the-art algorithms. After that, those features were used to predict the feelings of Music4All dataset lyrics from the Music Emotion Recognition (MER) dataset. This work tries to identify the importance of these features through transfer learning and combining pre-trained model BERT. After transfer learning, the BERT model is then applied to the dataset to improve the model's accuracy. The overall accuracy achieved is 92%.
Adrenal hemorrhage following DOACs therapy and first report in an APS-2 patient: Two Case Reports and Literature Review
Authors: Sheklabadi Elaheh , Sharifi Yasaman , Tabarraee Mahdi , Rabiee Parham , Tamehrizadeh Seyed Saeed , Hadaegh Farzad 
Published: April 2022

Abstract
Background:Adrenal hemorrhage (AH) is a rare condition that can result in a life-threatening medical emergency. This medical condition could be caused by several underlying factors, one of which is the use of anticoagulants. As far as we are aware, direct oral anticoagulant (DOAC) agents are a rare but possible cause of AH.Case presentation:Herein, we described two cases of AH due to DOACs. The first case was a 35-year-old woman with a past medical history of Hashimoto thyroiditis who was being treated with Apixaban due to the previous thrombosis. Her first symptoms of AH (November 2021) were strangely similar to symptoms of autoimmune Addison disease (AAD) which led to a confirmed diagnosis of autoimmune polyendocrine syndrome type 2 (APS-2). An abdominal MRI revealed an oval shape well-encapsulated cystic mass with a diameter of 20x14 mm with a thick and low signal intensity rim in the left adrenal gland, highly suggestive of sub-acute left-sided AH. Our second case was an 89-year-old woman who had been admitted to the hospital (August 2021) with low blood pressure and disorientation. At the beginning of her admission, the evaluation showed hyponatremia, and further evaluations confirmed adrenal insufficiency (AI). The patient reported Rivaroxaban usage for deep vein thrombosis prophylaxis after femur fixation surgery. Her abdominal CT scans showed bilateral adrenal masses highly suggestive of AH. Her follow-up examination showed persistent AI after three months.Conclusion:Given the history of our cases, physicians should be aware of AH in patients receiving DOACs, particularly in elderly patients who are at high risk of bleeding. It is also worth noting that AH can occur after a confirmed diagnosis of APS-2, and this is why patients need to be monitored closely.
Ecosystem services approach in national park planning: factors influencing the inhabitants’ perspectives on local natural resources and protected areas
Authors: Boćkowski Mariusz Daniel , Tusznio Joanna , Rechciński Marcin , Blicharska Małgorzata , Grodzińska-Jurczak Małgorzata 
Published: April 2022

Abstract
Despite changing paradigms on nature conservation, protected areas (PAs) such as national parks (NPs) remain key elements of systems of nature protection. Nowadays PAs are perceived as socio-ecological systems and there is a conviction that using ecosystem services (ES) approach (and follow-up derivatives) may help explaining social reluctance towards planned or existing PAs. In our study we focused on the planned Turnicki National Park (TuNP) in the far eastern part of the Polish Carpathians - an arena of intensive conservation conflict between proponents of park establishment and various local stakeholders. We examined the case through the ecosystem services perspective, using a questionnaire survey covering local communities around the planned TuNP. Further, we analyzed the interactions between perception of benefits from nature and attitudes towards NPs, as well as we assessed how social and economic status of local inhabitants shape attitudes towards PAs. Also, we discussed potential roles and viewpoints for a NP for a better coexistence with local social environments. We found important associations between attitudes towards parks and different factors, such as age, the length of living in a municipality, level of education and net income. Most notably, respondents who saw benefits of nature were more positive towards NPs in general and TuNP in specific, however those who prioritized provisioning services were more skeptical. The study has shown that using ES lens can help exploring the factors important in establishment and management of PAs and suggesting approaches to improve people’s attitudes towards PAs.
Activation of hippocampus mitochondrial Mn-SOD by a SIRT3 activator, honokiol, correlates with its deacetylation and upregulation of FoxO3a-PGC1α axis in a rat model of ammonia neurotoxicity
Authors: Trigun Surendra K , anamika Anamika 
Published: April 2022

Abstract
We have recently reported that honokiol (HKL), by activating mitochondrial SIRT3, restored ROS led deranged mitochondrial integrity associated with the pathogenesis of ammonia neurotoxicity induced moderate grade hepatic encephalopathy (MoHE). To delineate mechanism by which HKL does so, the present study describes activity vs acetylation level of the mitochondrial Mn-OD and its expression vs levels of its main transcription regulators; FOXO3a, PGC1α, in the hippocampus of the MoHE rat model of ammonia neurotoxicity, developed by administration of 100 mg/kg bw of thioacetamide i.p. for 10 days, and the MoHE rats treated with HKL (10 mg/Kg b.w.) for 7 days. As compared to the control, the hippocampus mitochondria from MoHE rats showed a significantly declined activity of MnSOD coinciding with the increased level of its acetylated form which however, could be restored back due the HKL treatment. Also, a significantly reduced expression of Mn-SOD in the hippocampus of those MoHE rats coincided with a similar decline in transcript level of FOXO3a and PGC1α. This was consistent with the reduced immunoreactivity of FOXO3a and PGC1α in the hippocampus DG, CA1 and CA3 regions of the MoHE rats. However, all these factors were observed to be restored back to their normal levels in the hippocampus of the MoHE rats treated with HKL. As HKL activates mitochondrial SIRT3, these findings suggest involvement of Sirt3 activation led deacetylation of MnSOD and upregulation of its transcription activators; FOXO3a and PGC1α in activating mitochondrial MnSOD in the hippocampus of the MoHE rat model of ammonia neurotoxicity.
A Clinical Study of Liposuction combined with Lymphovenous Anastomosis for Treatment of Breast Cancer-Related Lymphedema
Authors: Chang Kun , Xia Song , Liang Chen , Sun Yuguang , Xin Jianfeng , Shen Wenbin 
Published: April 2022

Abstract
Objective: In this work, we studied the clinical effect of liposuction combined with lymphovenous Anastomosis (LVAs) for treatment of breast cancer-related lymphedema (BCRL). Methods: We studied 158 patients with unilateral upper limb BCRL underwent liposuction combined with LVAs. Arm circumferences before and 7 days after the combined treatments were prospectively recorded. Circumferences of different upper extremities were measured before the procedure, 7 days after LVAs and during the follow-ups. Volumes were calculated with the frustum method. During the follow-ups, the conditions of patients’ treated arms, i.e. the frequency of erysipelas episodes and dependence on compression garments, were recorded. Results: The mean circumference difference between two upper limbs decreased significantly from M (P25, P75) 5.3 (4.1, 6.9) preoperatively to 0.5 (-0.8, 1.0) 7 days after treatments, while at follow-up 0.3 (-0.4,1.0). The mean volume difference decreased significantly from M (P25, P75) 838.3（662.4, 1129.0）preoperatively to 7.8 (-120.3, 151.4) 7 days after treatments, while at follow-up 43.7 (-59.4,161.1). The incidence of erysipelas also significantly decreased. 6.3% patients were already independent of compression garments during the past six months or even more. Conclusion: Liposuction combined with LVAs is an effective method for the treatment of BCRL.
Transumbilical single-site laparoscopic pyloromyotomy for pediatric hypertrophic pyloric stenosis
Authors: Ji Yi , Lai Xiaoqin , Xu Zhicheng 
Published: April 2022

Abstract
PurposeA new novel technique for the treatment of pediatric hypertrophic pyloric stenosis (HPS), transumbilical single-site laparoscopic pyloromyotomy with a single instrument (TUSSLP), was introduced. TUSSLP was compared with the trans-abdominal three-site laparoscopic pyloromyotomy (TATSLP) procedure.MethodsPatients with HPS who underwent TUSSLP and TATSLP between January 2016 and September 2020 were assigned to group A and group B, respectively. The data of perioperative clinical characteristics and postoperative follow-up results were retrospectively analysed and compared between the 2 groups.ResultsSixty-four patients were enrolled in this study. Of these patients, 29 (22 males, 7 females, 54.4±22.6 d) who received TUSSLP were assigned to group A. The remaining 35 (28 males, 7 females, 54.5±27.6 d) who received TATSLP were assigned to group B. The data of preoperative patient variables were comparable between the 2 groups (P>0.05). The mean operative time (ORT) was 28.1±5.6 min in group A, which was not significantly different from 25.8±3.1 min in group B (P=0.25). The other perioperative features were not significantly different between the 2 groups (P>0.05). During follow-up (39.1±14.7 m in group A and 35.4±16.1 m in group B, P=0.51), no significant difference was observed in the overall incidence of vomiting between the 2 groups (P=0.26).ConclusionsTUSSLP is a feasible and reliable minimally invasive method for HPS. It has the advantages of an improved cosmetic appearance. The postoperative follow-up results of TUSSLP are comparable with those of TATSLP.
Coral Sr/Ca records provide realistic representation of eastern Indian Ocean cooling during extreme positive Indian Ocean Dipole events
Authors: Pfeiffer Miriam , Watanabe Takaaki Konabe , Takayanagi Hideko , Cahyarini Sri Yudawati , Garbe-Schönberg Dieter , Watanabe Tsuyoshi 
Published: April 2022

Abstract
Extreme positive Indian Ocean Dipole (pIOD) events are amplified by non-linear ocean-atmosphere interactions and are characterized by pronounced cooling in the eastern equatorial Indian Ocean. These non-linear feedbacks are not adequately represented in historical products of sea surface temperatures that underestimate the magnitude of extreme pIOD events. Here, we present a sea surface temperature (SST) reconstruction based on monthly coral Sr/Ca ratios measured in two coral cores from Enggano Island (Indonesia), that lie in the eastern pole of the IOD. The coral SST reconstruction extends from 1930–2008 and captures the magnitude of cooling during extreme pIOD events as shown in recent satellite and reanalysis data of SST that include ocean dynamics. The corals indicate that the 1961 pIOD event was at least as severe as the 1997 event, while the 1967 pIOD was more comparable to the 2006 event. The magnitude 1963 pIOD is difficult to assess at present due to poor replication between coral cores, and may be comparable to either 1997 or 2006. Cooling during the 1972 pIOD was short-lived and followed by pronounced warming, as seen in the moderate pIOD event of 1982. A combination of coral SST reconstructions and an extension of new reanalysis products of SST to historical time scales could help to better assess the severity and impact of past pIOD events such as the ones seen in the 1960s.
Generation of nano-sized mist by passing a solution through dielectric barrier corona discharge
Authors: Watanabe Ryosuke , Tanaka Shiori , Miyaji Godai , Yoshino Daisuke 
Published: April 2022

Abstract
Plasma medicine, a therapeutic technology that uses atmospheric-pressure plasma, is attracting much attention as an innovative tool for the medical field. Most of the plasma biomedical tools use direct effects, such as heat, optical stimulation, and reactive chemical species, on the lesion. Nanoparticulation techniques using indirect action by plasma, i.e., generation of electric fields, have the potential to be applied to promote transdermal absorption, where drugs pass through the barrier function of skin and penetrate into internal tissues. Here, we show a method to generate the nano-sized mist by passing a solution through the corona-like discharge. This method enables us to produce the mist with generally less than 2.15 µm in particle size for both water-based and oil-based solutions. Efficiency of mist generation was influenced by the plasma-induced changes in physical and chemical characteristics, including electrical conductivity, viscosity, and chemical species. We anticipate the developed method for nano-sized mist generation to provide a technique in the applications of the transdermal absorption system, including those related to pharmaceuticals and cosmetics.
LINC01638 regulates miR-128/PDK1 to promotes cell proliferation and drug resistance in ovarian cancer
Authors: Ye Ying , Wang Hui 
Published: April 2022

Abstract
This study aims to explore the functional mechanism of LINC01638 in ovarian cancer (OC). The OC cell proliferation, viability and colony formation were respectively measured using CCK-8, MTT and colony formation assay. The cell cycle and apoptosis were both assessed using flow cytometry. Online bioinformatics tools were performed to predict the downstream gene of LINC01638. RNA pull down experiment and luciferase reporter assay were processed to verify the predictions. The expression of LINC01638, miR-128-3p and PDK1 in OC tissues and cells were detected using qRT-PCR and ISH analysis. The expressions of cisplatin-related proteins were determined by western blot. OC mice model was constructed to carry out in vivo experiment. LINC01638 was highly expressed in OC tissues and cells, and its high expression was related to poor OC prognosis. LINC01638 knockdown inhibited cell proliferation, colony formation and cisplatin resistance, promoted cell apoptosis and induced cell cycle arrest in OC cells. LINC01638 knockdown suppressed tumor growth, proliferation and cisplatin resistance and enhanced apoptosis in vivo. LINC01638 directly targeted miR-128-3p/PDK1 in OC cells. LINC01638 affected OC cell proliferation, survival and cisplatin resistance via combing miR-128-3p and promoting PDK1 expression.
A Predictive Nomogram Model for LARS after Rectal Cancer Resection
Authors: Shi Meiqin , Yan Mingfang , Lin Zhenmeng , Wu Zhiying , Zheng Huizhe 
Published: April 2022

Abstract
Background: The aim of this study was to identify risk factors associated with the low anterior resection syndrome (LARS) and to construct a nomogram capable of predicting the risk of LARS in patients who undergo rectal cancer resection. Methods: 538 patients who had undergone anterior resection were recruited as a development group at the Fujian Cancer Hospital between January 2017 and June 2019. In addition, 114 patients with rectal cancer who had been treated between February 2020 and April 2021 at the Zhongshan Hospital Affiliated to Xiamen University, were analyzed as a validation set to test the new nomogram. The diagnosis of LARS was determined using the LARS Score. Patients in the development set were grouped into two separate cohorts: those with major LARS and those with minor or no LARS. Multiple logistic regression was conducted to detect risk factors for major LARS. A nomogram was performed and verified by a calibration plot and analysis of a receptor operating characteristic (ROC) curve.Results: The prevalence of major LARS was 40.7%, of minor LARS was 28.6% and the proportion with no LARS was 30.7%. In multivariate analysis, female gender, preoperative chemoradiation, low tumor height, diverting ileostomy, postoperative anastomotic leakage were shown to be independently associated with major LARS occurring in patients after rectal cancer resection. The area under the curve (AUC) values of the nomogram were 0.726 (95% CI: 0.682-0.769) and 0.750 (95% CI: 0.655-0.845) in the development and validation sets, respectively. The calibration curves and Hosmer-Lemeshow goodness of fit tests showed that the model was acceptably accurate.Conclusions: There is a significant prevalence of major LARS following oncological rectal resection. A nomogram model based on risk factors could be valuable as a predictor of the probability of major LARS after rectal cancer surgery, and provides a guide that clinical staff can use to take preventive measures for high-risk patients.
Development and validation of a scale for the tendency to exercise in response to mood, eating, and body image cues: The Reactive Exercise Scale (RES)
Authors: De Young Kyle , Kambanis P. Evelyna , Bottera Angeline R. , Mancuso Christopher J. 
Published: April 2022

Abstract
Purpose: Earlier work on engaging in physical exercise when experiencing negative affect demonstrated robust associations with eating disorder (ED) behaviors and attitudes; however, measurement of the behavior was primitive. We report on the development of a self-report measure, the Reactive Exercise Scale (RES), that disentangles the tendency to engage in exercise in response to negative mood cues from the tendency to engage in exercise in response to eating and body image cues, which themselves may be associated with negative mood. The measure also assesses exercising in response to positive mood cues. Method: Exploratory factor analysis (FA) guided item and factor selection. Confirmatory FA in an independent sample supported a 3-factor solution – exercising in response to negative mood cues, eating and body image cues, and positive mood cues. Results: Results supported the construct validity of the RES subscales and indicated that exercising in response to negative mood cues may not uniquely relate to most aspects of ED psychopathology when accounting for eating and body image cues, which themselves are associated with negative mood. Conclusion: The RES allows for testing the unique relation of exercise to regulate negative emotion with ED constructs independent from the appearance-related motives for which exercise may also be used.
Validity and reliability of the Persian version of the Coping Assessment for Bereavement and Loss Experiences (CABLE)
Authors: Ebadi Abbas , Seraji Asal , Farahani Maryam Farmahini , Nia Hamid Sharif 
Published: April 2022

Abstract
Background and Aim:
The loss of loved ones following death, although very sad, becomes an inexperience for every person. Some people are very disabling and threatening to mourn. One of the factors that may distinguish people in response to grief is the coping strategies to deal with grief. The result of this study was designed to translate and determine the characteristics of psychological tools to assess coping with the experiences of grief and loss (28 items) in people living in Tehran, Iran.
Materials and Methods
This is a methodological study with a descriptive cross-sectional design that after obtaining written permission from the original developer and according to the WHO protocol, the Persian version of the questionnaire was completed by 480 experienced mourners living in Tehran in February 2021 to October 2021. Then, the Face validity, Content validity and Construct validity of questionnaire were assessed. Cronbach's alpha coefficient and Test-retest were used to determine the reliability.
Results
Cronbach's alpha for all items was 0.91 and intraclass correlation coefficient was 0.86, both of which indicate the reliability of the Persian version of the CABLE tool. Based on the maximum likelihood exploratory factor analysis and confirmatory factor analysis six factors were identified. The factors could explain 50% of the total variance observed. The model had an acceptable fit: GFI: 0.88, CFI: 0.96, IFI: 0.96, NFI: 0.92, PNFI: 0.82, RAMSEA: 0.058, CMIN/DF: 2.37 RMR: 0.056. Internal consistency and construct validity of the questionnaire were confirmed.
Conclusion
The findings of the present study indicate that the Persian version of CABLE is a tool with appropriate validity and reliability that can be used as a native tool to assess compliance with the experiences of grief and loss.
Severe Disease Activity Despite anti-TNF-α Treatment may Predispose to Post-colectomy Duodenitis Associated with Ulcerative Colitis
Authors: Fukata Masayuki , Sonoda Akira , Yoshimura Naoki , Sako Minako , Okano Soh , Saito Satoshi , Takazoe Masakazu , Furukawa Satomi , Okamoto Kinya , Yamana Tetsuo 
Published: April 2022

Abstract
BackgroundDiffuse mucosal inflammation in the duodenum that is distinct from peptic ulcer diseases has been repeatedly reported in patients with ulcerative colitis (UC). The pathogenesis of this complication remains uncertain, however, a colectomy for medically-refractory UC appears to trigger the duodenitis. We investigated the risk factors, treatments, and prognosis of UC-related duodenitis presented after colectomy. Methods　We performed a case series study of 152 patients with UC who underwent colectomy for the development of UC-related duodenitis between January 2011 and June 2020. Clinical and laboratory data, disease severity, medications were collected to see the associations with UC-related duodenitis. ResultsEleven UC-related duodenitis cases were identified among 55 colectomy cases of UC who received esophagogastroduodenoscopy (EGD) due to epigastric symptoms. Disease severity defined by CRP and partial Mayo score prior to colectomy was significantly higher in patients with UC-related duodenitis than the controls. Among the medications used before colectomy, only anti-TNF-α agents were significantly associated with the development of UC-related duodenitis (OR 5.4, 95% CI: 1.456 - 22.82, P=0.02). Most UC-related duodenitis patients responded to Mesalamine or corticosteroid, and did not experience relapses but four cases (36.4%) needed treatment escalations to control bleeding. Three UC-related duodenitis patients (27.3%) were eventually treated with biologics due to concomitant pouchitis and/or UC-like enteritis. ConclusionsUC patients with higher disease activity and the use of anti-TNF-α agents prior to colectomy appear to be at high risk of developing UC-related duodenitis. A relapse is rare in UC-related duodenitis but maintenance therapies may be needed if it’s complicated with pouchitis.