bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pre-extension demonstration and evaluation of food barley technology (Hordeum vulgare L.) in West and Kellem Wollega zones
Authors: Tasfa Hika , Umar Damaksa 
Published: April 2022

Pre extension demonstration of food barley varieties was carried out during 2010/11 and 2011/12 E.C cropping season with the objective of evaluating the best performed and preferred food barley varieties under farmer’s management condition. The trial was carried out selecting one kebele from each Anfilo, Hawa Gelan and Boji Dirmaji districts and selecting two kebeles from Seyo district. Three improved varieties of food barley (dinsho, abdane and biftu) with a local check were evaluated with full participation of FRG members under their management condition. The best fit variety was selected with the participants. The total of five (5) FRGs which incorporated a total of 59 male and 23 female was established. Each experimental plot had gross area of 100 m2 and rows spacing of 25 cm were used. All recommended agronomic practices were equally applied to all plots. Yield of varieties were collected and analyzed using descriptive statistics. Accordingly the yield performances of varieties were 28.66 qt/ha, 26.02 qt/ha, 23.96 qt/ha and 21.15 qt/ha for Dinsho, Abdane, Biftu and local respectively. Accordingly, the yield advantage of dinsho over local is 35.5% while the yield advantage of abdane over local is 23.02% and yield advantage of biftu over local is 13.28%. Farmers were enhanced to evaluate the technology using their own criteria. Accordingly they selected dinsho variety as their first choice by its grain yield, disease resistance, finger size and abdane variety secondly by its merits of early maturity, lodging tolerance and biftu and local thirdly and fourthly respectively. Generally based on farmer’s preference and objectively measured trait variety dinsho should be scaled up/out in Sayo, Hawa Galan, Anfilo and Bodji Dirmaji districts and similar agro ecology of West and Kellam wollega zones.
Res. Agric., Livest. Fish.9(1): 29-36, April 2022
Öğretmen Adaylarının Bireysel Ekolojik Ayak İzinin Bazı Değişkenlere Göre Değerlendirilmesi
Authors: Özyürek Cengiz , Demirci Filiz , Sarıgöl Julide , Tepe Banu , Güler Hatice 
Published: April 2022

Bu araştırmada Giresun Üniversitesi
eğitim fakültesinde öğrenim gören öğretmen adaylarının ekolojik ayak izi
seviyelerini belirlemek ve çeşitli değişkenler açısından bir değerlendirmesini
yapmak amaçlanmıştır. Araştırma tarama modelinde yapılmış, araştırmaya katılan
öğretmen adaylarının ekolojik ayak izlerini hesaplamak amacıyla veri toplama
aracı olarak “Ekolojik Ayak İzi Hesaplama Aracı” kullanılmıştır. Demografik bilgilerini öğrenmek için de
araştırmacılar tarafından hazırlanan “Kişisel Bilgi Formu” kullanılmıştır.
Araştırmanın çalışma grubu, 2017-2018 eğitim-öğretim yılında Giresun
Üniversitesi Eğitim Fakültesi 4. sınıf öğrenim düzeyindeki 259 öğretmen
adayından oluşmaktadır. Araştırmadan elde edilen bulgulara göre, öğretmen
adaylarının kişi başına düşen ekolojik ayak izi ortalamasının, dünyada kişi
başına düşen ayak izi ortalamasından daha fazla olduğu tespit edilmiştir.
Ayrıca, öğretmen adaylarının barınak bileşeni açısından kız olmasının ve
kentsel alanda yaşamış olmasının, hem
anketin tamamı hem de hizmetler bileşeni açısından anadolu lisesinden mezun
olmasının, hem anketin tamamı hem de mal ve hizmetler bileşeni açısından fen
bilgisi öğretmenliğinde öğrenim görmesinin ve gıda bileşeni açısından çevre
dersi almasının toplam ekolojik ayak izi değerlerini artırmada anlamlı
etkisinin olduğu söylenebilir.
Understanding the relationship between environment, agriculture and health: An interdisciplinary challenge
Authors: Waage Jeff 
Published: April 2022

In an editorial last year, Prof. Kathryn Monk explained the importance to environmental research of an interdisciplinary approach. She has asked me to share with readers some further, personal thoughts on this topic. I am an ecologist by training, but I spent much of my career managing agricultural research programmes in tropical regions. For the last ten years, I have held a position in a school of public health. This varied disciplinary experience has given me the opportunity to explore and understand interactions between environment, agriculture and human health. It is helpful to think of environment, agriculture, and health as points in a triangle, each having specific interactions with an adjacent sector, but also being influenced by more complex, three-way interactions. For environmental scientists, the interactions with agriculture are probably the most familiar. Extensive planting of crops like rice and oil palm has dramatic effects on biological diversity, water systems and their function, and soils. The importance of healthy environments to agriculture is repeatedly demonstrated. Thirty years ago, I had the opportunity to review the Indonesian national programme on integrated pest management in rice. Use of pesticides on rice was, paradoxically, causing severe outbreaks of pests like brown planthopper. The environmental processes behind this were actually quite complex. Soon after flooding, aquatic arthropods colonizing rice paddies provided a food source for generalist predators that moved in and built levels capable of suppressing subsequent pest invasion. Pesticides killed off this general predator community, while the pests, which lay their eggs inside plants, were less affected and their populations exploded in this predator-free environment (Settle et al. 1996). Integrated Pest Management (IPM) on rice, pioneered in countries like Indonesia, was for many years a leading example of the value of integrating environmental and agricultural research.Environmental scientists will be less familiar, perhaps, with the interactions between agriculture and health, so here is a short introduction. Agricultural systems have two impacts on health, which for historical reasons have been treated as separate disciplines in the health sector. They produce food that contributes to nutrition, which is usually, but not always, a health benefit, and they produce distinct health risks, including diseases associated with food and food production, and toxins associated with agriculture, such as the pesticide just mentioned.
Unraveling the Metabolic Derangements Occurring in Non-infarcted Areas of Pig Hearts With Chronic Heart Failure
Authors: Correia Cláudia , Wang Qing-Dong , Linhardt Gunilla , Carlsson Leif G. , Ulfenborg Benjamin , Walentinsson Anna , Rydén-Markinhutha Katarina , Behrendt Margareta , Wikström Johannes , Sartipy Peter , Jennbacken Karin , Synnergren Jane 
Published: April 2022

Graphical AbstractSummary of the metabolic and vascular derangements found in border and remote zones of pig hearts three months after the MI.
Association of ACE2 Polymorphisms and Derived Haplotypes With Obesity and Hyperlipidemia in Female Spanish Adolescents
Authors: Lumpuy-Castillo Jairo , Vales-Villamarín Claudia , Mahíllo-Fernández Ignacio , Pérez-Nadador Iris , Soriano-Guillén Leandro , Lorenzo Oscar , Garcés Carmen 
Published: May 2022

BackgroundIn the cardiovascular (CV) system, overactivation of the angiotensin converting enzyme (ACE) may trigger deleterious responses derived from angiotensin (Ang)-II, which can be attenuated by stimulation of ACE2 and subsequent Ang-(1-7) metabolite. However, ACE2 exhibits a high degree of genetic polymorphism that may affect its structure and stability, interfering with these cardioprotective actions. The aim of this study was to analyse the relationship of ACE2 polymorphisms with cardiovascular risk factors in children.MethodologyFive ACE2-single nucleotide polymorphisms (SNP), rs4646188, rs2158083, rs233575, rs879922, and rs2074192, previously related to CV risk factors, were analyzed in a representative sample of 12–16-year-old children and tested for their potential association with anthropometric parameters, insulin levels and the lipid profile.ResultsGirls (N = 461) exhibited lower rates of overweight, obesity, blood pressure, and glycemia than boys (N = 412), though increased plasma lipids. The triglycerides (TG)/HDL-C ratio was, however, lower in females. Interestingly, only in girls, the occurrence of overweight/obesity was associated with the SNPs rs879922 [OR 1.67 (1.02–2.75)], rs233575 [OR 1.98 (1.21- 3.22)] and rs2158083 [OR 1.67 (1.04–2.68)]. Also, TG levels were linked to the rs879922, rs233575, and rs2158083 SNPs, and the TG/HDL-C ratio was associated with rs879922 and rs233575. Levels of TC and LDL-C were associated with rs2074192 and rs2158083. Furthermore, the established cut-off level for TG ≥ 90 mg/dL was related to rs879922 [OR 1.78 (1.06–2.96)], rs2158083 [OR 1.75 (1.08–2.82)], and rs233575 [OR 1.62 (1.00–2.61)]. The cut-off level for TC ≥ 170 mg/dL was associated with rs2074192 OR 1.54 (1.04–2.28) and rs2158083 [OR 1.53 (1.04–2.25)]. Additionally, the haplotype (C-G-C) derived from rs879922-rs2158083-rs233575 was related to higher prevalence of overweight/obesity and TG elevation.ConclusionThe expression and activity of ACE2 may be essential for CV homeostasis. Interestingly, the ACE2-SNPs rs879922, rs233575, rs2158083 and rs2074192, and the haplotype (C-G-C) of the three former could induce vulnerability to obesity and hyperlipidemia in women. Thus, these SNPs might be used as predictive biomarkers for CV diseases and as molecular targets for CV therapy.
Antioxidant Peptides From Protein Hydrolysate of Marine Red Algae Eucheuma cottonii: Preparation, Identification, and Cytoprotective Mechanisms on H2O2 Oxidative Damaged HUVECs
Authors: Sun Kun-Lai , Gao Min , Wang Yue-Zhen , Li Xue-Rong , Wang Peng , Wang Bin 
Published: April 2022

Graphical AbstractThe mechanisms of antioxidant peptides EP4 and EP5 on protecting HUVECs from oxidative damage.
Combining Robot-Assisted Gait Training and Non-Invasive Brain Stimulation in Chronic Stroke Patients: A Systematic Review
Authors: Bressi Federica , Cinnera Alex Martino , Morone Giovanni , Campagnola Benedetta , Cricenti Laura , Santacaterina Fabio , Miccinilli Sandra , Zollo Loredana , Paolucci Stefano , Di Lazzaro Vincenzo , Sterzi Silvia , Bravi Marco 
Published: May 2022

Gait impairment is one of the most common disorders of patients with chronic stroke, which hugely affects the ability to carry out the activities of daily living and the quality of life. Recently, traditional rehabilitation techniques have been associated with non-invasive brain stimulation (NIBS) techniques, which enhance brain plasticity, with the aim of promoting recovery in patients with chronic stroke. NIBS effectiveness in improving gait parameters in patients with chronic stroke has been in several studies evaluated. Robotic devices are emerging as promising tools for the treatment of stroke-related disabilities by performing repetitive, intensive, and task-specific treatments and have been proved to be effective for the enhancement of motor recovery in patients with chronic stroke. To date, several studies have examined the combination of NIBS with robotic-assisted gait training, but the effectiveness of this approach is not yet well established. The main purpose of this systematic review is to clarify whether the combination of NIBS and robot-assisted gait training may improve walking function in patients with chronic stroke. Our systematic review was conducted according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. Studies eligible for review were identified through PubMed/MEDLINE, Embase, Scopus, and PEDro from inception to March 15, 2021, and the outcomes considered were gait assessments. Seven studies were included in the qualitative analysis of this systematic review, with a total population of 186 patients with chronic stroke. All studies specified technical characteristics of robotic devices and NIBS used, with high heterogeneity of protocols. Methodological studies have shown a significantly greater improvement in walking capacity recorded with 6MWT. Finally, research studies have highlighted a positive effect on walking recovery by combination of robot-assisted gait training with non-invasive brain stimulation. Furthermore, future studies should identify the best characteristics of the combined therapeutic protocols.Systematic Review RegistrationCRD42021244869.
Bridging the Transient Intraluminal Stroke Preclinical Model to Clinical Practice: From Improved Surgical Procedures to a Workflow of Functional Tests
Authors: Pinto Raquel , Magalhães Ana , Sousa Mafalda , Melo Lúcia , Lobo Andrea , Barros Pedro , Gomes João R. 
Published: April 2022

Graphical AbstractImproving translation of tMCAO mice model. Improvement of the surgical procedure, post-operative care and functional evaluation in the tMCAO mice, gives rise to a model with high parallel and translation into clinical reality. Induction of ischemia for 45-mins using smaller commercial filaments gives rise to uniform lesion volume that together with the improved post-operative care, decreases this model mortality. Furthermore, this allows for intensive long-term functional evaluation of mice. This way, clinical symptoms and ethology, as well as scales used to evaluate stroke, are mimicked in a mouse model.
A Three-Day Intervention With Granola Containing Cereal Beta-Glucan Improves Glycemic Response and Changes the Gut Microbiota in Healthy Individuals: A Crossover Study
Authors: Telle-Hansen Vibeke H. , Gaundal Line , Høgvard Benedicte , Ulven Stine M. , Holven Kirsten B. , Byfuglien Marte G. , Måge Ingrid , Knutsen Svein Halvor , Ballance Simon , Rieder Anne , Rud Ida , Myhrstad Mari C. W. 
Published: April 2022

Intake of soluble fibers including beta-glucan, is known to improve post-prandial glycemic response. The mechanisms have been attributed to the viscous gel forming in the stomach and small intestine, giving a longer absorption time. However, recent evidence suggests a link between intake of beta-glucan and improved glycemic regulation at subsequent meals through the gut microbiota. We investigated the short-term effect of granola with different amounts of cereal beta-glucan on glycemic response and gut microbiota. After a two-week run-in period (baseline), fourteen healthy, normal weight adults completed a dose-response dietary crossover study. Different amounts of cereal beta-glucan (low: 0.8 g, medium: 3.2 g and high: 6.6 g) were provided in granola and eaten with 200 ml low-fat milk as an evening meal for three consecutive days. Blood glucose and insulin were measured fasted and after an oral glucose tolerance test (OGTT) the following day, in addition to peptide YY (PYY) and glucagon-like peptide (GLP-2), fasting short chain fatty acids (SCFA) in blood, breath H2, and gut microbiota in feces. Only the intervention with medium amounts of beta-glucan decreased blood glucose and insulin during OGTT compared to baseline. Fasting PYY increased with both medium and high beta-glucan meal compared to the low beta-glucan meal. The microbiota and SCFAs changed after all three interventions compared to baseline, where acetate and butyrate increased, while propionate was unchanged. Highest positive effect size after intake of beta-glucan was found with Haemophilus, followed by Veillonella and Sutterella. Furthermore, we found several correlations between different bacterial taxa and markers of glycemic response. In summary, intake of granola containing 3.2 g cereal beta-glucan as an evening meal for three consecutive days reduced the glycemic response after an OGTT 0-180 min and changed gut microbiota composition. Since we cannot rule out that other fiber types have contributed to the effect, more studies are needed to further explore the effect of cereal beta-glucan on glycemic regulation.Clinical Trial Registration[www.clinicaltrials.gov], identifier [NCT03293693].
Risk Factors of Symptomatic COVID-19 in Samtse District, Bhutan
Authors: Lhendup Karma , Tsheten Tsheten , Rinzin Tshewang , Wangdi Kinley 
Published: May 2022

IntroductionAll Coronavirus disease 2019 (COVID-19) positive cases in Samtse District, Bhutan were isolated in the isolation facilities managed by the government hospitals. This study aimed to identify the socio-demographic risk factors for developing COVID-19 symptoms amongst these patients.Methods and MaterialsA secondary data of the COVID-19 positive cases from isolation facilities of Samtse District from 5 May to 7 September 2021 was used for this study. Survival analysis was carried out to estimate the cumulative probability of symptom onset time by each risk factor. Kaplan–Meier curves were used to estimate the probabilities for the onset of symptoms at different time points and a log-rank test was employed to assess the differences between covariates.ResultsA total of 449 patients were included, of which 55.2% were males and 73.3% (328) were aged &gt;18 years. The mean age was 42 years with a range of 3 months to 83 years. Forty-seven percent (213) reported at least one symptom. Common symptoms were fever (32.3%, 145), headache (31.6%, 142), and cough (30.1%, 135), respectively. Males were 64% less likely to be symptomatic than females [adjusted hazard ratio (aHR) = 0.36, 95% confidence interval (CI) 0.183–0.917]. Farmers (aHR = 3.17, 95% CI 1.119–8.953), and drivers and loaders (aHR = 3.18, 95% CI 1.029–9.834) were 3 times more likely to be symptomatic compared to housewives. Residents of Samtse sub-districts were 5 times more likely to be symptomatic than those living in other sub-districts (aHR = 5.16, 95% CI 2.362–11.254).ConclusionThe risk of developing COVID-19 symptoms was being fe male, farmers, drivers and loaders, and residents of the Samtse sub-district. These high-risk groups should be provided additional care when in isolation facilities.
Development of a Performance-Enhanced Hybrid Magnetorheological Elastomer-Fluid for Semi-Active Vibration Isolation: Static and Dynamic Experimental Characterization
Authors: Ali Abdelrahman , Salem Ayman M. H. , Muthalif Asan G. A. , Ramli Rahizar Bin , Julai Sabariah 
Published: April 2022

Magnetorheological elastomers (MREs) are a class of emerging smart materials in which their mechanical and rheological properties can be immediately and reversibly altered upon the application of a magnetic field. The change in the MRE properties under the magnetic field is widely known as the magnetorheological (MR) effect. Despite their inherent viscoelastic property-change characteristics, there are disadvantages incorporated with MREs, such as slow response time and the suspension of the magnetic particles in the elastomer matrix, which depress their MR effect. This study investigates the feasibility of a hybrid magnetorheological elastomer-fluid (MRE-F) for longitudinal vibration isolation. The hybrid MRE-F is fabricated by encapsulating MR fluid inside the elastomer matrix. The inclusion of the MR fluid can enhance the MR effect of the elastomer by providing a better response to the magnetic field and, hence, can improve the vibration isolation capabilities. For this purpose, an MRE-based coupling is developed, and isolation performance is investigated in terms of the linear transmissibility factor. The performance of the hybrid MRE-F was compared against two different MRE samples. The results show that further enhancement of MR-effect in MREs is possible by including MR fluid inside the elastomer. The hybrid MRE-F exhibited better stiffness change with the current increase and recorded the highest value of 55.911 N/mm. The transmissivity curves revealed that the MRE-F contributed to a broader shift in the natural frequency with a 7.2 Hz overall shift at 8.9 mT. The damping characteristics are higher in MRE-F, recording the highest percentage increase in damping with 33.04%. Overall, the results reveal the promising potential of hybrid MRE-F in developing MRE-based coupling for longitudinal vibration isolation.
Prokofiev and Fairy Tale
Authors: Ляхович Артём Владимирович 
Published: April 2022

Статья посвящена образной сфере сказки в творчестве Прокофьева, которая трактуется как ключевой локус его поэтики. Эта сфера рассмотрена в двух планах: сказочность как нарратив (в аспекте музыкально-инструментальной литературности, уподобления инструментального произведения литературной притче) и сказочность как творческий метод (в аспекте музыкального языка Прокофьева, его принципиальной установки на оригинальность и, соответственно, на необычность, остранение, чудо). Со вторым планом связана и сфера детства в музыке Прокофьева, тождественная миру, увиденному «как впервые». Нарратив трактуется двояко: в широком смысле - как комплекс взаимосвязанных музыкально-структурных и ассоциативных систем, восходящих к моделированию литературных форм и смыслов; и в узком - как звукоизображение рассказа, где Прокофьев по-новому продолжает «балладную» традицию романтиков. С литературностью прокофьевского нарратива резонирует роль театра в его творчестве и эстетике.
The article is devoted to the figurative sphere of fairy tales in the work of Prokofiev, which is interpreted as the key locus of his poetics. This sphere is considered in two modes: a fairy tale as a narrative (in the aspect of musical-instrumental literary, assimilating an instrumental work to a literary parable) and a fairy tale as a method of creation (in the aspect of Prokofiev's musical language, his fundamental attitude to originality and, accordingly, to uniqueness, defamiliarization, miracle). The second mode is also associated with the sphere of childhood in Prokofiev's music. It is identical to the world seen “as for the first time.” Narrative is interpreted in two ways: in a broad sense-as a complex of interrelated musical-structural and associative systems, ascending to the modeling of literary forms and meanings; and in the narrower sense, as a sound representation of the story, where Prokofiev continues the “ballad” tradition of composers of Romantism. The role of the theater in his work and aesthetics resonates with the literary nature of Prokofiev's narrative.