bluuebunny/crossref_metadata_2025_split huggingface dataset:
Análisis comparativo de dos traducciones de Une femme de Annie Ernaux
Authors: Pérez López Patricia , Sánchez Hernández Ángeles 
Published: December 2022

This article deals with the study of literary translation and, in particular, the process of retranslation, carrying out a research based on a balance between the theoretical and the empirical. Our work has been done on the basis of the observation of two Spanish translations of Annie Ernaux's Une femme(1987). The first one is carried out by Enrique Sordo (1988) shortly after its publication in France; the second one by Lydia Vázquez in 2020. The aim of which is based on looking for significant changes between these two translations, finding out what they are due to and verifying whether they correctly show the writer's idiolect. We analyze whether the variations may be due to gender issues of the translators, or whether they are due to the deepening of the knowledge that exists today of the French writer's work. We also seek to identify the different translational strategies adopted in the two target texts.
El presente artículo aborda el estudio de la traducción literaria y, en particular, observamos el proceso de retraducción, efectuando una investigación basada en el equilibrio entre lo teórico y lo empírico. Nuestro trabajo se fundamenta en la observación de dos traducciones en español de la obra Une femme(1987) de Annie Ernaux. La primera de ellas la lleva a cabo Enrique Sordo (1988) poco después de su publicación en Francia; la segunda traducción la realiza Lydia Vázquez en 2020. Revisamos las teorías sobre la traducción literaria y la retraducción para aplicarlas a nuestro estudio, cuyo objetivo se basa en buscar los cambios significativos entre estas dos traducciones, indagar a qué son debidos y verificar si muestran correctamente el idiolecto de la escritora. Analizamos si las variaciones pueden obedecer a cuestiones de género de los traductores, o son debidas a la profundización del conocimiento que existe hoy de la obra de la escritora francesa. Se busca, asimismo, identificar las diferentes estrategias traslativas adoptadas en los dos textos metas.
Cet article porte sur l'étude de la traduction littéraire et, en particulier, nous observons le processus de retraduction, en realisantune recherche basée sur un équilibre entre la théorie et l'empirique. Notre travail se fait sur l'observation de deux traductions espagnoles d'Une femme(1987) d'Annie Ernaux. La première est réalisée par Enrique Sordo (1988) peu après sa publication en France ; la seconde par Lydia Vázquez, en 2020. Le but est de rechercher des changements significatifs entre ces deux traductions, de trouver les raisons de ces changements et de vérifier s'ils montrent correctement l'idiolecte de l'auteur. Nous analysons si les variations peuvent être dues à des questions de genre des traducteurs ou bien à l'approfondissement de la connaissance qui existe aujourd'hui de l'œuvre de l'écrivaine française. Nous cherchons également à identifier les différentes stratégies de traduction adoptées dans les deux textes cibles.
METTL16-mediated translation of CIDEA promotes non-alcoholic fatty liver disease progression via m6A-dependent manner
Authors: Tang Jinhong , Zhao Xiangyun , Wei Wei , Liu Weiwei , Fan Huining , Liu Xiu ping , Li Yungai , Wang Long , Guo Jinghui 
Published: December 2022

Background
As the most prevalent chemical modifications on eukaryotic mRNAs, N6-methyladenosine (m6A) methylation was reported to participate in the regulation of various metabolic diseases. This study aimed to investigate the roles of m6A methylation and methyltransferase-like16 (METTL16) in non-alcoholic fatty liver disease (NAFLD).

Methods
In this study, we used a model of diet-induced NAFLD, maintaining six male C57BL/6J mice on high-fat diet (HFD) to generate hepatic steatosis. The high-throughput sequencing and RNA sequencing were performed to identify the m6A methylation patterns and differentially expressed mRNAs in HFD mice livers. Furthermore, we detected the expression levels of m6A modify enzymes by qRT-PCR in liver tissues, and further investigated the potential role of METTL16 in NAFLD through constructing overexpression and a knockdown model of METTL16 in HepG2 cells.

Results
In total, we confirmed 15,999 m6A recurrent peaks in HFD mice and 12,322 in the control. Genes with differentially methylated m6A peaks were significantly associated with the dysregulated glucolipid metabolism and aggravated hepatic inflammatory response. In addition, we identified five genes (CIDEA, THRSP, OSBPL3, GDF15 and LGALS1) that played important roles in NAFLD progression after analyzing the differentially expressed genes containing differentially methylated m6A peaks. Intriguingly, we found that the expression levels of METTL16 were substantially increased in the NAFLD model in vivo and in vitro, and further confirmed that METTL16 upregulated the expression level of lipogenic genes CIDEA in HepG2 cells.

Conclusions
These results indicate the critical roles of m6A methylation and METTL16 in HFD-induced mice and cell NAFLD models, which broaden people’s perspectives on potential m6A-related treatments and biomarkers for NAFLD.
Influence of Irrigation Schedules on Economics of Winter Wheat in Eastern Uttar Pradesh
Authors: Mishra Vipin , Denis D. M. , Singh Rajesh , Paul Anupriya 
Published: December 2022

This research was aimed to investigate the influence of irrigation schedules on the economic return of winter wheat during the Rabi season of years 2020-21 and 2021-22 for two consecutive years in Prayagraj, Uttar Pradesh, India. Irrigation was scheduled as influenced by limiting soil water conditions, climatological factors and factors of energy balance. Irrigation was scheduled as influenced by limiting soil water conditions; the maximum cost of wheat production 46702.14 Rs/ha was found with 396 mm of total water applied at irrigation level 0 % soil moisture depletion and maximum benefit cost ratio 1.93 was found with 316.8 mm of total water applied at irrigation level 20 % soil moisture depletion, while a minimum benefit cost ratio 1.30 was found with 79.2 mm of total water applied at irrigation level 80% soil moisture depletion. Irrigation was scheduled as influenced by climatological factors, the maximum cost of wheat production 46702.14 Rs/ha was found with 396 mm of total water applied at irrigation level (IW/CPE=1.75) and maximum benefit cost ratio 2.07 was found with 330 mm of total water applied at irrigation level (IW/CPE=1.5) while minimum benefit cost ratio 1.44 was found with 132 mm of total water applied at irrigation level (IW/CPE= 0.50). Irrigation was scheduled as influenced by factors of energy balance, the maximum cost of wheat production 50306.08 Rs/ha was found with 528 mm of total water applied at irrigation level (EB=0.50) and maximum benefit cost ratio 2.19 was found with 396 mm of total water applied at irrigation level (EB=0.75) while the minimum benefit cost ratio 1.72 was found with 198 mm of total water applied at irrigation level (EB=1.75). Total water applied and B:C ratio of wheat as influenced by limiting soil water conditions, climatological factors and factors of energy balance showed a quadratic relationship R2=0.90, 0.85, and 0.65, respectively.
Prevalence of Extended-spectrum Beta-lactamase Mediated Urinary Tract Infections in a Tertiary Hospital in Enugu, South East, Nigeria
Authors: Ugwu Luke Jideofor , Ogbuabor Alphonsus Ogbonna , Anyamene Chris Okwudilichukwu 
Published: December 2022

Extended-Spectrum Beta-Lactamase (ESBL) are a class of plasmid-mediated diverse, complex and rapidly evolving enzymes which hydrolyzes penicillins, monobactams and broad-spectrum cephalosporins. There is increasing prevalence of ESBL-producing bacteria globally with higher prevalence reported in developing countries. The present study was designed to determine the prevalence and antimicrobial sensitivity pattern of ESBL producing bacteria isolates in patients with Urinary Tract Infection (UTI) in Enugu. Urine samples were collected from a total of 284 subjects with self-reported UTI In the Enugu State University of Science and Technology Teaching Hospital, Enugu State, Nigeria between the periods of April to May,2019.Samples were analyzed for the presence of UTI and antimicrobial resistance pattern of ESBL-producing bacteria using standard methods. Data was analyzed by descriptive statistics using SPSS version 23 (IBM Corp Armok, NY). A total of 145 strains of Staphylococcus aureus (n= 19). Escherichia coli (n=52), Klebsiella pneumonia (n=45), Pseudomonas aeruginosa (n =12), Enterococcus faecalis (n=9) and Proteus mirabilis (n=8), were isolated from 132 subjects giving a UTI prevalence rate of 34.6%. Forty-nine (49) ESBL-producing strains comprising Staphylococcus aureus (n=5), Escherichia coli (n=15), Klebsiella pneumonia (n=16), Pseudomonas aeruginosa (n=13), Enterococcus faecalis (n=8) and Proteus mirabilis (n=7) were implicated in UTI accounting for 46.8%ESBL-producing bacteria mediated UTI. There is a high prevalence of ESBL-producing bacteria induced UTI. This portends a great danger to the management of bacterial infections.
Efficacy of a Brief Tele–Cognitive Behavioral Treatment vs Attention Control for Head and Neck Cancer Survivors With Body Image Distress
Authors: Graboyes Evan M. , Maurer Stacey , Balliet Wendy , Li Hong , Williams Amy M. , Osazuwa-Peters Nosayaba , Yan Flora , Padgett Lynne , Rush Angie , Ruggiero Kenneth J. , Sterba Katherine R. 
Published: December 2022

ImportanceAlthough 1 in 4 head and neck cancer (HNC) survivors experience clinically significant body image distress (BID), a psychosocial morbidity that adversely affects quality of life, effective interventions for these patients are lacking.ObjectiveTo evaluate the acceptability and preliminary efficacy of BRIGHT (Building a Renewed ImaGe after Head and neck cancer Treatment), a brief tele–cognitive behavioral therapy, at reducing BID among HNC survivors.Design, Setting, and ParticipantsThis parallel-group pilot randomized clinical trial recruited adult HNC survivors with BID between August 13, 2020, and December 9, 2021, from the Medical University of South Carolina HNC clinic during a routine survivorship encounter. Data were analyzed from May 3 to June 16, 2022.InterventionsBRIGHT consisted of 5 weekly psychologist-led video tele–cognitive behavioral therapy sessions. Attention control (AC) consisted of dose- and delivery-matched survivorship education.Main Outcomes and MeasuresChange in HNC-related BID was assessed using IMAGE-HN (Inventory to Measure and Assess imaGe disturbancE–Head and Neck), a validated patient-reported outcome (score range, 0-84, with higher scores indicating greater HNC-related BID). Clinical response rate was measured as the proportion of patients with a clinically meaningful change in IMAGE-HN scores.ResultsOf the 44 HNC survivors with BID allocated to BRIGHT (n = 20) or AC (n = 24), the median (range) age was 63 (41-80) years, and 27 patients (61%) were female. Patients rated BRIGHT’s acceptability highly (all metrics had a mean rating of ≥4.5/5), and 19 of 20 patients (95%) receiving BRIGHT were likely or highly likely to recommend it to other HNC survivors with BID. BRIGHT decreased HNC-related BID from baseline to 1 month postintervention relative to AC (mean model-based difference in change in IMAGE-HN score, –7.9 points; 90% CI, –15.9 to 0.0 points) and from baseline to 3 months postintervention relative to AC (mean model-based difference in change in IMAGE-HN score, –17.1 points; 90% CI, −25.6 to −8.6 points). At 3 months postintervention, the clinical response rate of BRIGHT was 6.6-fold higher than AC (model-based odds ratio, 6.6; 90% CI, 2.0-21.8). The improvement in HNC-related BID for BRIGHT vs AC at 3 months was clinically significant, and the effect size was large (Cohen d, −0.9; 90% CI, −1.4 to −0.4).Conclusions and RelevanceIn this pilot randomized clinical trial, BRIGHT was acceptable, may result in a clinically meaningful improvement in HNC-related BID, and showed a high clinical response rate. These promising preliminary data support conducting a large efficacy trial to establish BRIGHT as the first evidence-based treatment for HNC survivors with BID.Trial RegistrationClinicalTrials.gov Identifier: NCT03831100
A Universal Size Design Principle for Stretchable Inorganic Electronics to Work Consistently under Different Interface Conditions
Authors: Li Shuang , Lan Yuqun , Huang YongAn , Chen Yuli , Su Yewang 
Published: December 2022

AbstractStretchable inorganic electronics are usually designed and calibrated under free interface condition, while the interface conditions between the devices and skins/organs in practical applications are rather complex (free, slidable, or bonded) and may switch among them. In the ideal situation, the mechanical and electrical performances have to be consistent under different interface conditions, to ensure the accuracy and robustness of the devices. Here, the effect of interface conditions on the mechanical and electrical performances is studied for stretchable inorganic electronics with different configurations by theoretical analysis, finite element analysis and experiment. A universal size design principle is proposed for stretchable inorganic electronics to work consistently under different interface conditions, i.e., the period length of the devices/interconnects has to be the same order of magnitude as the encapsulation thickness or less. To ensure the comfort of human skin/organs, micron‐scale geometrical design is necessary for epidermal electronics according to the above designed principle. This finding is of great significance for ensuring the accuracy and robustness of stretchable inorganic electronics in practical applications.
Completely Anisotropic Ultrafast Optical Switching and Direction‐Dependent Photocarrier Diffusion in Layered ZrTe5
Authors: Seo Sung Bok , Nah Sanghee , Sajjad Muhammad , Song Jiacheng , Singh Nirpendra , Suk Sang Ho , Baik Hionsuck , Kim Sanghoon , Kim Geun‐Ju , Kim Jung‐Il , Sim Sangwan 
Published: December 2022

AbstractLayered nanomaterials with in‐plane anisotropy exhibit unique orientation‐dependent responses to external stimuli, enabling the development of novel devices with additional degrees of freedom. In particular, their anisotropic optical properties enable ultrafast nanophotonic modulators to be controlled by light polarization. However, achieving high controllability is still challenging due to incomplete optical anisotropy in most materials. Here, this work presents a completely anisotropic, ultrafast optical modulation in zirconium pentatelluride (ZrTe5), a layered nanomaterial that has recently attracted renewed attention. The transient absorption (TA) microscopy reveals anisotropic ultrafast picosecond optical modulation in a broad range of 1.2–2.2 eV. In particular, at a certain photon‐energy of 1.62 eV, complete on/off switching with a near‐unity degree of anisotropy is achieved solely by changing the light polarization, suggesting that ZrTe5 is a promising material for polarization‐selective high‐speed optical modulators. The theoretical analysis of the transition dipole moments attributes this sharp anisotropy to strongly polarization‐dependent excited‐state absorption. Furthermore, this work directly observes direction‐dependent photocarrier transport using scanning TA microscopy. It yields the anisotropic diffusivity, mobility, and diffusion lengths of the photocarriers, which are essential parameters for designing devices. Therefore, this work provides a comprehensive understanding of the anisotropic optical characteristics of ZrTe5 on ultrafast timescales.
Novel, Green, and Scalable Aqueous Synthesis of Yellow–Green Emitting Cs3Cu2Cl5 Scintillator and its Application in High‐Resolution TFT Panel for X‐Ray Imaging Detector
Authors: Wang Zhicheng , Guo Jiale , Lin Qi‐Sheng , Rao Guanghui , Zhao Jingtai , Yang Chengzhang , He Weixiang , Wang Chujie , Zhang Zhijun 
Published: December 2022

AbstractCopper‐based metal halide scintillators have received increasing attention due to their high light yield and nontoxicity. However, the synthetic methods are still not feasible for actual commercialization for the difficulty in scaling up and the absence of green chemical footprint. Herein, we report a new, simple, aqueous synthetic method for the mass production of highly purified and crystallized Cs3Cu2Cl5 powder by a room‐temperature reaction between a saturated aqueous solution of CsCl and a saturated hydrochloric acid solution of CuCl. The product exhibits a photoluminence peak centering at 527 nm (FWHM = 106.7 nm) and a quantum yield (PLQY) of 97%. A prototype X‐ray imaging detector is fabricated by coupling a large area scintillation screen prepared by blade coating of Cs3Cu2Cl5 powder and a commercial thin‐film transistor (TFT) panel (16 cm × 13 cm, 125 µm pixel size) with readout circuit. The device exhibits a high spatial resolution of 4 lp mm−1, exceeding the theoretical limit of the TFT panel, and an excellent dynamic imaging ability. In short, this work demonstrates an efficient novel synthetic method of Cs3Cu2Cl5 and its application as X‐ray imaging device, providing an applicable solution for its future commercialization.
Halide Perovskite: A Promising Candidate for Next‐Generation X‐Ray Detectors
Authors: Wu Ya , Feng Jiangshan , Yang Zhou , Liu Yucheng , Liu Shengzhong (Frank) 
Published: December 2022

AbstractIn the past decade, metal halide perovskite (HP) has become a superstar semiconductor material due to its great application potential in the photovoltaic and photoelectric fields. In fact, HP initially attracted worldwide attention because of its excellent photovoltaic efficiency. However, HP and its derivatives also show great promise in X‐ray detection due to their strong X‐ray absorption, high bulk resistivity, suitable optical bandgap, and compatibility with integrated circuits. In this review, the basic working principles and modes of both the direct‐type and the indirect‐type X‐ray detectors are first summarized before discussing the applicability of HP for these two types of detection based on the pros and cons of different perovskites. Furthermore, the authors expand their view to different preparation methods developed for HP including single crystals and polycrystalline materials. Upon systematically analyzing their potential for X‐ray detection and photoelectronic characteristics on the basis of different structures and dimensions (0D, 2D, and 3D), recent progress of HPs (mainly polycrystalline) applied to flexible X‐ray detection are reviewed, and their practicability and feasibility are discussed. Finally, by reviewing the current research on HP‐based X‐ray detection, the challenges in this field are identified, and the main directions and prospects of future research are suggested.
Defoliation at seedling stage enhances maize yield by reducing lodging
Authors: Xu Jiayi , Zou Xiaojin , Xu Huasen , Gong Liang , Sun Zhanxiang , Zhang Lizhen , Niu Shiwei , Feng Liangshan , Han Lei , Wang Ruigang 
Published: December 2022

AbstractLodging greatly reduces maize (Zea mays L.) grain yield and harvest efficiency. We conducted a 3‐year (2018–2020) field experiment in Fengcheng city, Liaoning, China to investigate the effects of maize seedling defoliation on lodging resistance and grain yield. Two cultivars, Liangyu99 and Hongshuo, were tested without (control treatment) and with defoliation at seedling stage (V4 stage: DS treatment). Compared with the control, DS significantly (p < 0.05) decreased stalk lodging by 63.2%–77.9% and 51.0%–75.1%, contributing to the increase in grain yield by 4.94%–7.76% and 9.75%–19.6% for Liangyu99 and Hongshuo, respectively, during 2018–2020. The improvement of maize lodging resistance by seeding defoliation was mainly due to changes in plant morphology. On average, 12.0% and 21.9% declines in plant and ear heights, respectively, were observed and the number of internodes below the ear was reduced by 1–2 units for both cultivars with DS. A comparison of cultivars revealed that the increase in grain yield with defoliation was approximately twofold greater for Hongshuo than for Liangyu99. The greatest yield increase due to seedling defoliation was observed in 2018, when the yield was lowest with the nontreated control. However, in environments where lodging is less common, suppression of early vegetative growth would probably make little, if any, contribution to maize yield. These results suggest that defoliation of maize seedlings could be a profitable agronomic practice for maize grown in areas that experience frequent lodging.
A novel homozygous nonsense NDNF variant in Kallmann syndrome
Authors: Kotan Leman Damla , Yildiz Melek , Turan Ihsan , Celiloglu Can , Yuksel Bilgin , Topaloglu Ali Kemal 
Published: December 2022

AbstractKallmann syndrome (KS) is a rare genetic disease characterized by pubertal failure and olfactory defects. Although many genes associated with KS have been reported, most are rare. Recently, heterozygous inactivating mutations in the neuron‐derived neurotrophic factor gene (NDNF) were reported to cause KS. Here, we present a 14‐year‐old Kurdish boy with KS who has a novel homozygous nonsense c.1251C>A (p.Tyr417Ter) variant in NDNF. The variant was not observed in reference population databases and was predicted to be deleterious. Segregation analysis performed with Sanger sequencing indicated the autosomal recessive inheritance of the clinical phenotype. His heterozygous parents have experienced timely pubertal development and normal reproductive features. This study reported the first homozygous truncating NDNF variant, enabling the direct observation of the clinical consequences of predictively absent NDNF function. These results support the contention that the inactivating mutations in NDNF cause KS, and provide additional evidence for the complex inheritance of KS.
Benign goiters requiring thyroidectomy as the signal for PTEN hamartoma tumor syndrome diagnosis
Authors: Wang Xia , Moore Colin , Bao Yong 
Published: December 2022

AbstractPTEN hamartoma tumor syndrome (PHTS) is a rare genetic cancer and tumor predisposition syndrome. Due to the wide spectrum of clinical manifestations and variable age at onset, the pathways leading to a PHTS diagnosis are difficult and highly variable. Many patients were found to have PHTS after a cancer diagnosis, missing the opportunity of prevention or enhanced cancer screening. This retrospective study evaluated a PHTS cohort followed in a high‐risk surveillance clinic in a comprehensive cancer institution. A significant portion of the patients (60.9%, 14/23) had at least one cancer diagnosis (average age 34.6 years at diagnosis). A significant portion (78.3%, 18/23) were affected with clinically significant goiters (age 27.9 years), and many (60.9%, 14/23) had partial or total thyroidectomy (age 27.1 years). The average age at goiter diagnosis or thyroidectomy is younger than a cancer diagnosis. In 12 individuals who were affected with clinically significant goiter and cancer, all cancers were diagnosed after the thyroid disease (6.3 years). As clinically significant thyroid nodules in childhood or early young adulthood are common in PHTS, but uncommon for general population, these early onset thyroid nodules may alert the clinician to initiate PHTS‐targeted evaluation and genetic testing.