bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is language ability associated with behaviors of concern in autism? A systematic review
Authors: Chan Charissa Ying Zhen , Williams Katrina , May Tamara , Wan Wei Herng , Brignell Amanda 
Published: November 2022

AbstractThis review systematically synthesized evidence on the association between structural language ability and behaviors of concern (BoC) in autism. Four databases were searched for studies that included >10 autistic participants, measures of structural language (content and/or form of language) and BoC, and an analysis of their association. BoCs included self‐injurious behavior (SIB), aggression, tantrums, and externalizing behavior. Methodological quality of studies were assessed using the Newcastle Ottawa Scale. Forty‐five publications (n = 11,961) were included. Forty studies were cross‐sectional and five were prospective cohort studies. Over 70% of the studies investigating expressive language and SIB (n = 10), aggression (n = 5), tantrums (n = 3), and externalizing behavior (n = 17) reported an inverse association, where lower expressive language ability was associated with increased BoC. Eleven out of sixteen studies of combined expressive and receptive language reported an inverse relationship with SIB or aggression. All outcomes were rated as moderate to very low certainty of evidence. This review highlights evidence showing an inverse association between expressive or combined language ability and SIB, and externalizing behavior in autism. However, further high‐quality studies that use standardized, consistent measures of language and behavior and investigate longitudinal associations are needed. Early detection and support for reduced structural language difficulties have substantial potential to assist in reducing BoC.
Electrochemically Induced Borate Allotropes for Expedite Charge Transfer in Lithium‐Ion Batteries and Hydroxyl Ion Capture Activity in Flexible Pseudocapacitor
Authors: Kasiviswanathan Kavibharathy , Lakshmanan Kumaresan , Chenrayan Senthil , Woo Lee Chang , Rangasamy Baskaran , Vediappan Kumaran 
Published: November 2022

AbstractDespite lithium‐ion battery (LIB) and supercapacitor materials have gone through numerous enhancements, achieving high energy density as well as power density together is still a dream for the industries. In this scenario, herein we report, boric acid coated α−MnO2 anode with 1288 mAh g−1 at 0.1 C at the initial cycle and of an average discharge capacity of 570 mAh g−1 at 0.1 C over 20 cycles, high‐rate capability and 100 % Coulombic efficiency after 60 cycles for LIB. The Li+ diffusion coefficient estimated from GITT and EIS measurements reveals that the H3BO3 coated α−MnO2 electrode has superior Li‐ion kinetics (
∼10−10 cm2 s−1) than bare α−MnO2. Coin cells with boric acid coated α−MnO2 electrode are able to power up red and blue LEDs continuously for about 24–32 hours. The ex‐situ investigations reveal an interesting self‐assembled active electrode‐electrolyte interfacial bridging Li4B2O5 layer formation. This significant active layer allows free migration of lithium ions across interface that leads to good cyclability. In flexible supercapacitor, the boric acid coated α−MnO2 yields excellent cyclability over 500 cycles with specific capacitance of 35 F g−1 at 1 A g−1 and further 200 cycles at 30° acute angle with 21 F g−1 at 1 A g−1. The research overthrows the significance of boric acid in conversion reactions for active interfacial bridging layer in LIB and hydroxyl ion capturing agent in flexible supercapacitor.
Development and validation of a stability‐indicating, single HPLC method for sacubitril–valsartan and their stereoisomers and identification of forced degradation products using LC–MS/MS
Authors: Vijaykumar Cholleti , Kumar Yalavarti Ravindra , Aparna Pasula , Rao Pydimarry Surya Prakash 
Published: November 2022

AbstractThe aim of this research work was to develop and validate a stability‐indicating, single reversed‐phase HPLC method for the separation of five impurities, including enantiomers, diastereomers, and degradation products in sacubitril–valsartan tablets. The method was developed using a Chiralcel OJ‐RH column (150 × 4.6 mm, 5 μm) at 45°C with a gradient program of (T/%B) 0.01/25, 10.0/25, 25/38, 37.0/45, 39.0/25, and 45.0/25 at a flow rate of 0.8 ml/min. Mobile phase A consisted of 1 ml of trifluoroacetic acid in 1000 ml of Milli‐Q water. Mobile phase B consisted of 1 ml of trifluoroacetic acid in a mixture of acetonitrile and methanol in the ratio of 950:50 (v/v). Sacubitril, valsartan, and their five impurities were monitored at 254 nm. Degradation was not observed when sacubitril–valsartan was subjected to heat, light, hydrolytic, and oxidation conditions. In acid degradation study (1 N HCl/60°C/2 h) impurity 1 (m/z 383.44) was formed, and in base degradation study (0.1 N NaOH/40°C/1 h) impurities 1 and 5 (m/z 265.35) were formed; both impurities were confirmed using LC–MS. The degradation products, enantiomers, and diastereomers were well separated from sacubitril and valsartan, proving the stability‐indicating power of the method. The developed method was validated per the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use guidelines. The inter‐ and intra‐day percentage relative standard deviation for sacubitril, valsartan, and their five impurities was less than 5.2%, recovery of the five impurities was between 93 and 105%, and linearity was ≥0.999. The limit of detection was 0.030–0.048 μg/ml, and the limit of quantification was 0.100–0.160 μg/ml.
Tell me where you come from and I know what makes you tick: Managing the consumer personality–satisfaction link in diverse cultures
Authors: Mooradian Todd , Matzler Kurt , Strobl Andreas , Teichmann Karin 
Published: November 2022

AbstractMarketing programs that evoke high satisfaction and marketing success in one culture often fail in others, but the understanding of those cultural differences is insufficient. The question of how culture is linked to consumer satisfaction is still not answered satisfactorily. One promising paradigm for exploring such questions comes from progress in cross‐cultural personality psychology. Thus, we examine the influence of individual‐level cultural orientations on personality, and the role of personality and affect in satisfaction formation across cultures. Based on experimental data, we show that a high individualism orientation triggers higher levels of extraversion; a high uncertainty‐avoidance orientation triggers higher levels of neuroticism. Based on field data from Japan, Spain, and the United States, we identify equivalent relationships amongst personality‐related antecedent processes shaping satisfaction indicating universality across these cultures. The findings demonstrate the usefulness of cross‐cultural personality psychology theory and methods for understanding and predicting consumer responses to marketing actions across cultures.
Procedural simplification of left atrial appendage occlusion using the VersaCross connect system: First in‐human experience
Authors: Perrin Nils , McAlister Cameron , Tsang Michael , Mondésert Blandine , Ibrahim Réda , Saw Jacqueline 
Published: November 2022

AbstractBackgroundLeft atrial appendage occlusion (LAAO) has emerged over the last two decades as an efficient and safe alternative to oral anticoagulation for stroke prevention. However, LAAO remains challenging due to the variety of anatomies and the multiple steps required to complete the procedure.AimsWe report the first series of in‐human experience of the new all‐in‐one VersaCross Connect system designed to access the left atrium in conjunction with the delivery sheath for deployment of the WATCHMAN FLX device.MethodsWe prospectively included the first nine consecutive cases of LAAO using the new VersaCross Connect system for WATCHMAN FLX device implantation at the Montreal Heart Institute and Vancouver General Hospital and collected procedural duration (defined as time from femoral access to closure) and time from transseptal puncture to device delivery.ResultsVersaCross Connect system use for WATCHMAN FLX implantation was successful in all patients. No procedural complication was reported. Mean procedural time was 31 ± 6.3 min with a fluoroscopy time of 6.7 ± 4.9 min. The mean delay between the transseptal puncture and device implantation was 12.2 ± 1.9 min.ConclusionsWe showed that the VersaCross Connect system was safe and successfully used in all first nine cases. This new system helped improve the efficiency of the procedure.
Quality characteristics and antioxidant activities of Korean traditional rice and quinoa‐based wine “Makgeolli”
Authors: Jeon Eun Bi , Song Min Gyu , Kim So Hee , Choi Jae‐Suk , Lee Jung‐Suck , Park Shin Young 
Published: November 2022

AbstractBackground and ObjectivesMakgeolli is a traditional Korean rice wine that is brewed by fermenting a mixture of steamed rice and Nuruk. Quinoa products contain polyphenols, including phenolic acids, flavonoids, and tannins, which make up bioactive secondary plant metabolites that contribute to diverse physiological properties, such as antimicrobial, antioxidant, and antitumor activities. The preparation of rice‐based Makgeolli (RM) and quinoa‐added Makgeolli (QM) were obtained by combining rice and quinoa in ratios 1:1 (RM; control: without supplement). This study sought to assess the physicochemical, microbiological, antioxidant, and taste tests of RM and QM during a 6‐day fermentation period.FindingThe alcohol content increased steadily until Day 6 (10.7%–10.3%). From the start of fermentation to Day 2 of fermentation, the number of lactic acid bacteria (LAB) in RM and QM increased rapidly (p < .05), with no significant increase thereafter (p > .05). 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) and 2,2‐azino‐bis(3‐ethylbenzthiazoline‐6‐sulfonic acid) (ABTS) radical scavenging activities were significantly (p < .05) higher in QM (DPPH: 81.01%, ABTS: 91.46%) than in RM (DPPH: 43.65%, ABTS: 53.85%). The average result of iron(II) chelating activity for RM was 39.81%, while for QM was 47.09%. Moreover, superoxide dismutase scavenging activity of both RM and QM were 41.07% and 56.23%, respectively. There were no significant differences in color, smell, appearance, and overall acceptability between RM and QM (p > .05). However, taste values were significantly higher (p < .05) in QM than in RM (5.9 vs. 4.3).ConclusionMakgeolli supplemented with quinoa owing to its good physicochemical and microbiological characteristics, including high antioxidant properties and good consumer acceptance.
Using Artificial Neural Networks to Predict Physical Properties of Membrane Polymers
Authors: Bestwick Tate , Beckmann Jessica , Camarda Kyle V. 
Published: November 2022

AbstractMembrane polymers are a promising technology for use in many challenging gas separation applications. The techniques of computer‐aided molecular design can be used to search through the massive molecular space of heteropolymers and develop a set of likely candidate repeat units matching specific physical property targets. However, reasonably accurate property prediction algorithms are needed, but these algorithms must be very fast in order to be combined with an optimization framework. Artificial neural networks (ANNs), a branch of machine learning, are applied in this work to predict the physical properties of polymers. All of the physical properties investigated were found to be predicted by ANNs with R2 scores exceeding 0.82.
Cortical synapses of the world's smallest mammal: An FIB/SEM study in the Etruscan shrew
Authors: Alonso‐Nanclares Lidia , Rodríguez J. Rodrigo , Merchan‐Perez Angel , González‐Soriano Juncal , Plaza‐Alonso Sergio , Cano‐Astorga Nicolás , Naumann Robert K. , Brecht Michael , DeFelipe Javier 
Published: November 2022

AbstractThe main aim of the present study was to determine if synapses from the exceptionally small brain of the Etruscan shrew show any peculiarities compared to the much larger human brain. We analyzed the cortical synaptic density and a variety of structural characteristics of 7,239 3D reconstructed synapses, using using Focused Ion Beam/Scanning Electron Microscopy (FIB/SEM). We found that some of the general synaptic characteristics are remarkably similar to those found in the human cerebral cortex. However, the cortical volume of the human brain is about 50,000 times larger than the cortical volume of the Etruscan shrew, while the total number of cortical synapses in human is only 20,000 times the number of synapses in the shrew, and synaptic junctions are 35% smaller in the Etruscan shrew. Thus, the differences in the number and size of synapses cannot be attributed to a brain size scaling effect but rather to adaptations of synaptic circuits to particular functions.
Incorporation of a Multi‐Valent Aptamer into Electrochemical Biosensors to Achieve an Improved Performance for Thrombin Analysis in Blood Serum
Authors: Zhu Man , Xu Fan , Miao Siyuan , Xie Chongyu , Li Hui , Li Shaoguang , Xia Fan 
Published: November 2022

AbstractThe electrochemical aptamer‐based (E‐AB) biosensor usually has a long reaction time when detecting thrombin. This work reports the design of an E‐AB biosensor with dual recognition sites to quickly detect thrombin. Specifically, two specific recognition sites of thrombin were used to design three aptamer sequences (TBA‐15, TBA‐29 and TBA‐U), followed by fabrication of corresponding sensors. First, we tested these three types of biosensors in tris buffer solution, and found that the response time of the TBA‐U sensor to the same concentration of thrombin was about 2 hours, which is shorter than TBA‐15 and TBA‐29 sensors. Then, we also did the same test in 50 % diluted serum with 500 nM thrombin. The response time of the TBA‐U sensor was about 2 hours, which is still faster than the 3 hours of TBA‐15 sensor and the 5.5 hours for TBA‐29 sensor. In addition, in terms of dynamic range and specificity, TBA‐U has good performance.
Diabetic foot resurfacing using microvascular tissue transfer from lateral thoracic region
Authors: Chang Lan Sook , Jang Dong Woo , Kim Youn Hwan , Kim Sang Wha 
Published: November 2022

AbstractAimsDiabetic foot ulcer is a major complication of diabetes mellitus and amputation is often needed. Since mortality rate after amputation is comparatively high, saving diabetic foot is required not only for preserving function and life quality, but also for decreasing mortality rate. This study was designed to analyse experience of limb salvage in patients with diabetic foot using free flaps from the lateral thoracic region over a 10‐year period.Materials and MethodsBetween 2009 and 2018, 297 cases of diabetic foot underwent surgical procedures. We analysed the 83 cases who underwent free flap from lateral thoracic region. Patient data were reviewed retrospectively.ResultsA total of 83 patients, 56 of them males, were included in this study. Age of patients ranged from 27 to 80 years. Twenty patients underwent percutaneous transluminal angioplasty procedures. The latissimus dorsi muscle sparing technique was used in 7 cases. A thoracodorsal artery perforator flap was used in 68 cases. A thoracodorsal artery perforator chimaeric flap was performed in 8 cases. The flap survival rate was 98.8% and the limb salvage rate was 96.4%. The mean follow‐up was 6.5 years. During follow‐up 14 patients suffered recurrence of foot ulcers.ConclusionsTen‐year experience of using flaps from the lateral thoracic region revealed superior outcomes in terms of flap survival and limb saving compared to those in a recent meta‐analysis and other reports. Long vascular pedicle technique and the chimaeric technique might be the alternative methods for multiple or vascular insufficient diabetic foot defects.
Investigating the social embeddedness of criminal groups: Longitudinal associations between masculine honour and legitimizing attitudes towards the Camorra
Authors: Travaglino Giovanni A. , Friehs Maria‐Therese , Kotzur Patrick Ferdinand , Abrams Dominic 
Published: November 2022

AbstractThe embeddedness of criminal groups within communities accrues from their ability to establish legitimacy, particularly among young people. A prototypical example are mafia claims to political authority in Italy. Intracultural Appropriation Theory proposes that embeddedness is partly derived from criminal groups’ ability to embody cultural ideologies of masculine honour, and to reinforce these ideologies in society through their actions. We tested these propositions using a three‐wave longitudinal design involving Italian adolescents from the Campania region (N1stwave = 1,173). We also examined an alternative explanation rooted in individuals’ generic acceptance of group‐based hierarchies, i.e., social dominance orientation. The longitudinal design enabled us to examine for the first time both between‐ and within‐person processes. Between‐person results indicated that higher levels of the masculine honour ideology and social dominance were associated with stronger legitimizing attitudes towards the Camorra, a mafia‐type group. Within‐person effects revealed a positive reciprocal association between masculine honour and legitimizing attitudes. These findings emphasize the importance of culture‐specific ideologies in sustaining the legitimacy of criminal groups.
Combining amperometry and mass spectrometry as a dual detection approach for capillary electrophoresis
Authors: Böhm Daniel , Koall Martin , Matysik Frank‐Michael 
Published: November 2022

AbstractDual detection concepts (DDCs) are becoming more and more popular in analytical chemistry. In this work, we describe a novel DDC for capillary electrophoresis (CE) consisting of an amperometric detector (AD) and a mass spectrometer (MS). This detector combination has a good complementarity as the AD exhibits high sensitivity, whereas the MS provides excellent selectivity. Both detectors are based on a destructive detection principle, making a serial detector arrangement impossible. Thus, for the realization of the DDC, the CE flow was divided into two parts with a flow splitter. The DDC was characterized in a proof‐of‐concept study with ferrocene derivates and a nonaqueous background electrolyte. We could show that splitting the CE flow was a suitable method for the instrumental realization of the DDC consisting of two destructive detectors. By lowering the height of the AD compared to the MS, it was possible to synchronize the detector responses. Additionally, for the chosen model system, we confirmed that the AD was much more reproducible and had lower limits of detection (LODs) than the MS. The LODs were identical for the DDC and the single‐detection arrangements, indicating no sensitivity decrease due to the CE flow splitting. The DDC was successfully applied to determine the drug and doping agent trimetazidine.
Multi‐scale drivers of spatial patterns in floodplain sediment and phosphorus deposition
Authors: Diehl Rebecca M. , Underwood Kristen L. , Triantafillou Shayla P. , Ross Don S. , Drago Stephanie , Wemple Beverley C. 
Published: November 2022

AbstractThe capacity for floodplains to capture sediment and filter pollutants is spatially variable and depends on the complex interactions of geomorphic, geologic, and hydrologic variables that operate at multiple scales. In this study, we integrated watershed‐scale and local assessments to improve our understanding of floodplain depositional patterns. We developed a dataset of event‐scale observations of sediment and phosphorus deposition rates distributed at 129 plots across large environmental gradients of floodplain topography, valley geometry, and watershed characteristics in the Lake Champlain Basin, Vermont. Plot‐scale observations were used to evaluate the cross‐scale influence of environmental factors and were summarized into site‐scale averages to explore regional trends. Consistent with other studies, floodplain deposition generally scaled with drainage area, but trends were longitudinally discontinuous and depended on variations in valley width and slope. While variability in deposition patterns at the watershed‐scale was large (average of 2.0 (0.2–9.8) kg sediment m−2 yr−1; average of 1.4 (0.2–6.5) g phosphorus m−2 yr−1), the range in deposition rates locally across a floodplain was greater (average of 4.6 (0.06–21.7) kg sediment m−2 yr−1; average of 6.4 (0.1–41.1) g phosphorus m−2 yr−1). Local variables that described the proximity to water and sediment sources, and frequency with which the plot was activated by a flood, had the greatest relative contribution to boosted regression tree models of phosphorus deposition rates, highlighting the importance of river–floodplain connectivity for floodplain functioning and the profound impact of human activities that limit such connectivity. Patterns identified in our study may guide prioritization of restoration and conservation practices designed to capture sediment and phosphorus on floodplains.
Phase‐field‐based multiple‐distribution‐function lattice Boltzmann method for incompressible two‐phase flows
Authors: Zhan Chengjie , Chai Zhenhua , Shi Baochang 
Published: November 2022

AbstractIn this work, a multiple‐distribution‐function lattice Boltzmann method (MDF‐LBM) for the incompressible two‐phase flows with large density ratios is proposed by considering the governing equations as a coupled convection‐diffusion system. In this method, the phase‐field and convection‐diffusion‐based Navier–Stokes equations can be correctly recovered through the direct Taylor expansion. In addition, the pressure is obtained from the first‐order moment of the distribution function, and the incompressibility is satisfied automatically. Furthermore, we also develop a local computing scheme for the velocity gradient, which can be used to calculate some physical quantities, for example, the strain rate tensor, velocity divergence and vorticity. In our simulations, two simple phase‐capturing benchmark tests without including flow field are first conducted to validate the present MDF‐LBM. When coupling the flow field, we consider the deformation of a square droplet, and find that compared to the commonly used single LBM, the present MDF‐LBM can preserve the incompressibility and mass conservation much better. Then the layered Poiseuille flow is also used to test the present MDF‐LBM, and the numerical results are in good agreement with the analytical solutions and some available results. Finally, the problems of the droplet impact on a thin liquid film as well as the two‐dimensional and three‐dimensional Rayleigh–Taylor instability with the large deformation are further investigated to show the capability of present MDF‐LBM in the study of the complex two‐phase flows.