bluuebunny/crossref_metadata_2025_split huggingface dataset:
ОСОБЛИВОСТІ ПРОЯВУ ТА ПРОФІЛАКТИКИ У ВІЙСЬКОВОСЛУЖБОВЦІВ УРГЕНТНОЇ АДИКЦІЇ
Authors: Мороз В. 
Published: August 2022

У статті досліджується проблема ургентної адикції ‒ однієї з форм залежної поведінки у військовослужбовців, яка в умовах високих навантажень може призводити до різних психологічних наслідків, і, як результат, до зниження ефективності військово-професійної діяльності.
В ході теоретичного аналізу визначено основні чинники, що призводять до розвитку ургентної залежності, розкрито характерні ознаки даної адикції та її наслідки для військовослужбовців.
Chest CT findings in COVID 19 disease in relation with duration of illness: A study of two hundred cases.
Authors: Saha Chinmoy Kumar , Sarker RN , Saha Dipa , Haque Mohammad Ahsanul , Alam Mohammad Mahabubul , Basak Prabir Mohan , Pal Bablu Kumar , Alam Md Shah 
Published: August 2022

Chest CT scans of 200 symptomatic patients infected with COVID 19 from different health facilities and home were reviewed for common CT findings in relationship with their clinical symptoms, comorbidities and the time between symptom onset and the initial CT scan was studied in this cross-sectional study. Cases were categorized into three groups according to the timing of HRCT, 10 cases were in early (0-2days), 56 cases in intermediate (3-5days) and 110 cases were in late (6-12days) groups. Chest CT scan images showed bilateral peripheral ground glass opacities 96.63%, pulmonary consolidations 15.9%. Notably 29.54% patient had normal CT scan chest and 60% of them were imaged at early phase. With a longer duration of symptoms, chest CT findings were more typical including GGO, consolidation with greater total lung involvement. Bilateral peripheral GGO was observed in 20% patients at early phase while 53.57% and 64.54% were observed at intermediate and late phase of illness. Among the symptoms cough and dyspnea were observed more related with typical CT changes (95%). Diabetes and Hypertension (58% of patients) were the leading comorbidities that were found related with GGO and other typical CT findings. Mean time duration between symptom onset and positive RT PCR, CT scan changes were 4.79 and 7.55 respectively.
Central Medical College Journal Vol 5 No 2 Jul 2021 PP 70-75
PREDICTION OF GOODS STOCK SYSTEM IN SANTI ELECTRONIC SHOP WITH DOUBLE MOVING AVERAGE METHOD
Authors: Sari Fita , Fauziah Rizky , EIIyany Hommy Dorthy 
Published: August 2022

Abstract : Santi Electronic Store is one of the shops that sells the needs of electronic products for the community. This store requires predictions that can estimate the number of items to be sold, this shop often experiences a shortage of electronic products that will be purchased by customers. In designing the system using the Double Moving Average (DMA) forecasting method to support decisions in determining the amount of stock of electronic products to be sold for the next month. This forecasting application is made using Visual Basic Net 2010 programming language with Microsoft Office Access database. From making the system an application can be produced that can control optimal and economical demand and with a high level of accuracy and can predict the number of requests for electronic products in the coming period at the Santi Electronic Store so that the forecast results can help trading businesses so that stock does not occur requests for electronic products at the Santi Electronics Store.
Keywords : Hole; Multiple Moving Average; Prediction. Abstrak : Toko Elektronik Santi merupakan salah satu toko yang menjual kebutuhan produk elekronik bagi masyarakat. Toko ini memerlukan prediksi yang bisa memperkirakan jumlah barang yang akan dijual, pada Toko ini sering mengalami kurangnya persediaan produk eIekronik yang akan dibeIi peIanggan. Dalam perancangan sistem menggunakan metode peramalan DoubIe Moving Average (DMA) untuk proses pendukung keputusan dalam menentukan jumlah stok produk elekronik yang akan dijual untuk buIan berikutnya. Aplikasi Peramalan ini dibuat menggunakan bahasa pemrograman visualbasic net 2010 dengan database microsoft office acces. Dari pembuatan sistem dapat dihasilkan sebuah aplikasi yang dapat mengendalikan permintaan yang optimal dan ekonomis dan dengan tingkat akurasi yang tinggi serta dapat memprediksi jumlah permintaan produk elekronik pada periode yang akan datang di Toko Elektronik Santi sehingga hasil prakiraan peramalan tersebut dapat membantu usaha dagang agar tidak terjadi kehabisan stok permintaan produk elektronik pada Toko Elektronik Santi. Kata kunci : Multiple Moving Average; Prediksi; Permintaan.
Eğitim Programları Ve Öğretim Yüksek Lisans Programına İlişkin Öğretim Üyesi Ve Öğrenci Görüşleri
Authors: ÖKMEN Burcu , ŞAHİN Şeyma , BOYACI Zeynep , KILIÇ Abdurrahman , ADIGÜZEL Abdullah 
Published: August 2022

Bu
araştırmanın amacı; EPÖ yüksek lisans programına ilişkin öğretim üyesi ve
öğrenci görüşlerini belirlemektir. Araştırma betimsel bir araştırma olup nitel
araştırma yöntemi kullanılmıştır. Araştırmanın çalışma grubunu bir devlet
üniversitesinde Eğitim Fakültesinde görev yapan 8 akademisyen ve aynı
üniversitenin Sosyal Bilimler Enstitüsü EPÖ yüksek lisans programından mezun
veya tez aşamasında olan 13 öğrenci oluşturmaktadır. Araştırma verileri görüşme ve odak grup görüşme
teknikleri kullanılarak toplanmıştır.
Verilerin analizinde içerik analizi yöntemi kullanılmıştır. Araştırma
bulguları; “EPÖ yüksek lisans programının genel yapısına ilişkin görüşler”,
“EPÖ yüksek lisans programının öğrenme öğretme sürecine ilişkin görüşler”, “EPÖ
yüksek lisans programında öğrenci değerlendirme sürecine ilişkin görüşler”,
“EPÖ yüksek lisans programında yer alacak derslere ilişkin görüşler”, “EPÖ
yüksek lisans programında eğitim verecek öğretim üyelerine ilişkin görüşler” ve
“EPÖ yüksek lisans programı mezunlarının istihdam alanlarına ilişkin görüşler”
olmak üzere altı ana başlık altında toplanmıştır. Araştırma sonuçlarına göre
çeşitli öneriler geliştirilmiştir.
Case report: Spontaneous coronary artery dissection in a man with Ehlers–Danlos syndrome
Authors: Li Qiao , Ma Min , He Yong 
Published: August 2022

BackgroundSpontaneous coronary artery dissection (SCAD), as a medical emergency, represents one of the non-atherosclerotic causes of an acute coronary syndrome (ACS). It often occurs in young and middle-aged females and is a rarity among male patients. Yet, it is easily misdiagnosed or missed even though it has one of the highest in-hospital mortality rates.Case summaryHere, we present a young male patient admitted to the emergency department of our hospital due to a complaint of acute chest pain. During his hospitalization, we utilized several tools, including imaging modalities, genetic analyses, and clinical strategies, to ensure a proper diagnosis and management of the patient. The results indicated that the patient suffered from SCAD, as well as vascular Ehlers–Danlos syndrome (vEDS). Unfortunately, the patient died of SCAD-related sudden cardiac death (SCD) on the ninth day before the DNA analysis results were obtained. Despite a global effort and huge progress in the clinical characterization of SCAD, as well as patients’ assessments, its pathophysiology remains poorly understood, with a significant recurrence risk and no specific disease-modifying therapy.ConclusionVascular Ehlers–Danlos syndrome, as an inherited connective tissue disorder characterized by congenital connective tissue dysplasia, is a rare and particularly challenging monogenetic disease. It can cause life-threatening changes, including arterial dissections and ruptures, and lead to early death due to COL3A1 pathogenic variants. It is also a rare cause of SCAD. Currently, the gold standard for SCAD diagnosis is coronary angiography (CAG).
Optimal dose of tirzepatide for type 2 diabetes mellitus: A meta-analysis and trial sequential analysis
Authors: Yu Yunfeng , Hu Gang , Yin Shuang , Yang Xinyu , Zhou Manli , Jian Weixiong 
Published: August 2022

ObjectiveThe purpose of this study is to evaluate the optimal dose of tirzepatide (TZP) for the treatment of type 2 diabetes mellitus (T2DM) by meta-analysis and trial sequential analysis (TSA).MethodsClinical trials of TZP for T2DM were obtained by searching 8 databases with a time limit from database creation to May 2022. Mean differences (MD) and 95% confidence intervals (95%CI) were used for continuous variables, and relative risk (RR) and 95%CI were used for dichotomous variables.ResultsCompared with TZP 5 mg, meta-analysis showed that TZP 10 mg significantly reduced glycosylated hemoglobin type A1c (HbA1c) (MD −0.24, 95%CI −0.31~-0.17, P &lt; 0.00001), fasting serum glucose (FSG) (MD −5.82, 95%CI −8.35~-3.28, P &lt; 0.00001) and weight (MD −2.47, 95%CI −2.95~-1.98, P &lt; 0.00001), and TZP 15 mg significantly reduced HbA1c (MD −0.37, 95%CI −0.44~-0.29, P &lt; 0.00001), FSG (MD −8.52, 95%CI −11.07~-5.98, P &lt; 0.00001) and weight (MD −4.63, 95%CI −5.45~-3.81, P &lt; 0.00001). Compared with TZP 10 mg, TZP 15 mg dramatically reduced HbA1c (MD −0.12, 95%CI −0.19~-0.05, P = 0.001), FSG (MD −2.73, 95%CI −5.29~-0.17, P = 0.04) and weight (MD −2.18, 95%CI −2.67~-1.70, P &lt; 0.00001). The TSA indicated that the benefits observed in the current information set were conclusive, except for the FSG of “TZP 15 mg vs. TZP 10 mg”. In terms of safety endpoints, meta-analysis revealed that there was no significant difference in the serious adverse events (AEs), major adverse cardiovascular events-4 (MACE-4), cardiovascular death, hypertension, cancer and hypoglycemic of the three dose groups of TZP. Compared with TZP 5 mg, TZP 10 mg increased total adverse events (RR 1.06, 95%CI 1.01~1.11, P = 0.03) and gastrointestinal (GI) AEs (RR 1.17, 95%CI 1.03~1.33, P = 0.02), and TZP 15 mg increased total AEs (RR 1.10, 95%CI 1.05~1.15, P = 0.0001). There were no significant differences in total AEs and GI AEs for TZP 15 mg compared to TZP 10 mg. The TSA demonstrated that the total AEs of “TZP 15 mg vs. TZP 5 mg” were conclusive.ConclusionsTZP 15 mg &gt;TZP 10 mg &gt; TZP 5 mg in terms of lowering glycemia and reducing weight. TZP 5 mg &gt; TZP 10 mg = TZP 15 mg in terms of safety. On this basis, we recommend TZP 5 mg as the first-choice dose for patients with T2DM to minimize AEs while reducing glycemia and weight. If patients cannot effectively control their glycemia after taking TZP 5 mg, it is recommended to take TZP 15 mg directly to achieve the best effect of glycemic reduction. However, most of the included studies have the background of basic medication, the independent efficacy and safety of different doses of TZP still need to be tested.Systematic review registrationUnique Identifier: CRD42022341966.
Long-term use of renin-angiotensin-system inhibitors after acute myocardial infarction is not associated with survival benefits: Analysis of data from the Korean acute myocardial infarction registry-national institutes of health registry
Authors: Park Chan Soon , Yang Han-Mo , Kang Jeehoon , Han Jung-Kyu , Park Kyung Woo , Kang Hyun-Jae , Koo Bon-Kwon , Seung Ki-Bae , Cha Kwang Soo , Seong In-Whan , Rha Seung-Woon , Jeong Myung Ho , Kim Hyo-Soo 
Published: August 2022

IntroductionRenin-angiotensin-system inhibitors (RASi) have shown survival benefits after acute myocardial infarction (MI), but the role of routine long-term use of RASi remains unclear. Thereby, we explored the therapeutic effects of RASi medication at 1-year follow-up from acute MI.MethodsUsing the nationwide Korea Acute Myocardial Infarction Registry-National Institutes of Health (KAMIR-NIH) registry, we included and analyzed 10,822 subjects. Patients were stratified into those taking RASi at 1-year follow-up (n = 7,696) and those not taking RASi at 1-year follow-up (n = 3,126). Patients were followed up for 2-years from the 1-year follow-up; 2-year all-cause mortality and cardiac mortality were analyzed as primary and secondary outcomes, respectively.ResultsThe use of RASi at 1-year follow-up was not associated with decreased all-cause mortality (log-rank P = 0.195) or cardiac mortality (log-rank P = 0.337). In multivariate analyses, RASi medication at 1-year follow-up did not reduce all-cause mortality (P = 0.758) or cardiac mortality (P = 0.923), while RASi medication at discharge substantially reduced 1-year all-cause and cardiac mortality. Treatment with either an angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker at 1-year follow-up did not show survival benefits from 1-year follow-up, respectively. The use of RASi at 1-year follow-up did not show a prognostic interaction between previous history of chronic kidney disease, post-MI acute heart failure, concomitant use of beta-blockers at 1-year follow-up, or 1-year LVEF.ConclusionAcute MI patients taking RASi at 1-year follow-up were not associated with improved 2-year all-cause mortality or cardiac mortality from the 1-year follow-up. This study provides valuable information regarding tailored medication strategy after acute MI.Clinical trial registration[www.ClinicalTrials.gov], identifier [KCT0000863].
Evaluation of organic geochemical characteristics and experiments of thermal pressure simulation of Jurassic coal measure source rocks in the Yanqi Basin
Authors: Yao Yaming , Zhao Fei , Zhang Junmin , Zhao Juanjuan 
Published: August 2022

The Yanqi Basin is a coal-bearing basin in Western China. In order to determine the hydrocarbon generation potential of the Jurassic source rocks in this area, the organic matter composition of coal-measure mudstone, carbonaceous mudstone and coal rocks, the yields of liquid and gaseous hydrocarbons, and the comparison of hydrocarbon sources were studied by means of hydrocarbon-generating thermal simulation experiments. The results showed that the micro-composition of the Jurassic coal rocks in the Yanqi Basin showed the characteristics of rich vitrinite-inertinite and poor chitinite + saprolite components; however, the micro-composition of the mudstone showed the characteristics of poor inertinite and rich vitrinite–chitinite + saprolite components. The Jurassic mudstone has a wide distribution range of hydrogen and oxygen indexes, among which the hydrogen index is distributed between 2 and 266 mg/gTOC, and the oxygen index is distributed between 3 and 183 mg/g TOC. The organic matter in the mudstone belongs to Type II2-III kerogen. The hydrogen index of coal is distributed in the range of 100–300 mg/gTOC, which is obviously larger than that of mudstone. The total liquid hydrocarbon yield of the coal rock is the highest (43.2 mg/gTOC), followed by mudstone (16.4–20.4 mg/gTOC), while that of the carbonaceous mudstone is the lowest (5.36 mg/gTOC). In addition, mudstone has the highest yield of gaseous hydrocarbons, followed by coal, while that of carbonaceous mudstone is the lowest. The oil-source comparison showed that the Jurassic crude oil has a certain affinity with its main source rocks (mudstone, carbonaceous mudstone, and coal). At the same time, the comparison results of steroid and terpene biomarker parameters with crude oil showed that the Middle and Lower Jurassic mudstone, carbonaceous mudstone, and coal rock in this area are all source rocks and the Badaowan Formation mudstone is the main hydrocarbon source.
Anti-Mullerian Hormone (AMH) and adenomyosis: Mini-review of literature of the last 5 years
Authors: Gulino Ferdinando Antonio , Dilisi Valentina , Capriglione Stella , Cannone Francesco , Catania Francesco , Martire Francesco Giuseppe , Tuscano Attilio , Gulisano Marianna , D’Urso Valentina , Di Stefano Alessandra , Cimino Monia Caterina , Filippini Maurizio , Latella Silvia , Sammarini Margaret , Musmeci Giulia , Palumbo Marco Antonio 
Published: August 2022

IntroductionAdenomyosis is a form of endometriosis characterized by the presence of endometrial tissue in the myometrium. The correlation between anti-Mullerian hormone (AMH) expression and adenomyosis is unclear. Few studies investigated this possible correlation with promising results. The aim of this mini-review is to illustrate the potential prognostic and therapeutic role of AMH in adenomyosis.Materials and methodsA study protocol was completed conforming to the Preferred Reporting Items for Reviews and Meta-Analyses (PRISMA) guidelines for systematic reviews. We performed an electronic databases search from each database’s inception from August 2017 to August 2022 for full-text articles and published abstracts. For database searches, the following main keywords were the following text words: “adenomyosis” or “uterine endometriosis” [Mesh] AND “AMH” or “anti-mullerian hormone”.ResultsFrom the literature search, 8 abstracts of studies were retrieved and independently screened for inclusion by three authors. It was found that the most common therapeutic strategies (such as adenomyomectomy and high-intensity focused ultrasound (HIFU) do not alter AMH levels. Moreover, a higher expression of the AMH receptor II was observed in adenomyotic tissue, hence a possible therapeutic use of AMH was hypothesized.ConclusionThe available evidence shows an unclear relationship between adenomyosis and AMH. Probably, women with adenomyosis have lower levels of AMH and the surgical treatment (adenomyomectomy, HIFU) does not alter this characteristic, therefore in all of them, ovarian function is not influenced.
Risk factors of new vertebral compression fracture after percutaneous vertebroplasty or percutaneous kyphoplasty
Authors: Cheng Yuanpei , Cheng Xiaokang , Wu Han 
Published: August 2022

BackgroundNew vertebral compression fracture (VCF) may occur in patients who underwent percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fracture (OVCF). However, the risk factors of new VCF remain controversial. The research aimed to analyze the risk factors of new VCF after PVP or PKP.MethodsFrom August 2019 to March 2021, we retrospectively analyzed the patients who underwent PVP or PKP for OVCF at our institution. Age, gender, body mass index (BMI), smoking, drinking, hypertension, diabetes, fracture location, surgical method, Hounsfield unit (HU) value, preoperative degree of anterior vertebral compression (DAVC), bisphosphonates, bone cement volume, bone cement leakage, and cement distribution were collected. The risk factors were obtained by univariate and multivariate analysis of the data.ResultsA total of 247 patients were included in the study. There were 23 patients (9.3%) with new VCF after PVP or PKP. Univariate analysis showed that age (p &lt; 0.001), BMI (p = 0.002), fracture location (p = 0.030), and a low HU value (p &lt; 0.001) were significantly associated with new VCF after PVP or PKP. A low HU value was an independent risk factor for new VCF after PVP or PKP obtained by multivariate regression analysis (OR = 0.963; 95% CI, 0.943–0.984, p = 0.001).ConclusionsIn this study, a low HU value was an independent risk factor of new VCF after PVP or PKP.
Bacterial isolates from diabetic foot ulcers and their antimicrobial resistance profile from selected hospitals in Addis Ababa, Ethiopia
Authors: Atlaw Asegdew , Kebede Habtamu Biazin , Abdela Abdurezak Ahmed , Woldeamanuel Yimtubezinash 
Published: August 2022

IntroductionInfected diabetic foot ulcer (IDFU) is a worldwide problem associated with diabetes mellitus. It could lead from soft tissue infection to bone infection and is a leading cause of lower limb amputation. Gram-negative and Gram-positive bacteria, including anaerobic bacteria and fungi, are considered potential causes of infection. The early diagnosis of DFU infection and appropriate treatment based on the identification of the pathogens and their antimicrobial susceptibility pattern is important for good prognosis. Therefore, the purpose of this study was to isolate the bacteria that infect foot ulcers in selected Hospitals and determine their antimicrobial resistance profile.MethodAn institutional-based multicenter, cross-sectional study was conducted in selected Hospitals in Addis Ababa, Ethiopia, from November 2020 to May 2021. A sterile swab was used to collect samples from the foot ulcer and a sterile needle to collect pus. Isolates were identified by culture, Gram-staining, and a series of biochemical tests. For each bacterial species identified, the antibiotic profiling was determined by the Kirby-Bauer disk diffusion method.Resultsone hundred and twenty-seven pathogenic bacteria were isolated from samples taken from 130 patients with a diabetic foot ulcer. Sixty-eight percent had growth of multiple microorganisms. Two-thirds (66.7%) of the isolates were gram-negative bacteria. The predominant bacterial species were S. aureus 25.19% (32/127), Pseudomonas species 18.89% (24/127), and Escherichia coli 16.53% (21/127). Overall, 92.9% (118/127) of the isolates were identified as multi-drug resistant. Gram-positive isolates were susceptible to chloramphenicol, clindamycin, and amikacin. Gram-negative isolates were also sensitive to chloramphenicol, aztreonam, and amikacin.ConclusionThe majority of bacteria isolated from patients presenting with Diabetic foot ulcer infections were found to be multi-drug resistant in the study sites of the current study. The results demonstrate the importance of timely identification of infection of diabetic foot ulcers, proper sample collection for identification of the pathogens and for determining their antibiotic susceptibility pattern before initiating antimicrobial treatment
Distributed robust optimization scheduling of a steel plant integrated energy system considering the uncertainty of byproduct coal gas
Authors: Li Fan , Li Yuxiao , Niu Tao , Fang Sidun , Wu Wenguo 
Published: August 2022

The steel plant integrated energy system (SPIES) is an important form in the steel industry. Improving the utilization efficiency of steam, electricity, coal gas and other energy flows is of great significance for both economic and environmental benefits. In this paper, a SPIES scheduling model is established according to the operation characteristics of coal gas holders, boilers and other equipment in steel plants. Meanwhile, to cope with the uncertainty of byproduct coal gas, this paper adopts an imprecise Dirichlet model (IDM) to construct a fuzzy set containing multisource coal gas production information. Then, according to duality theory and the big-M method, the original distributed robust optimization (DRO) model is transformed into a traditional mixed integer linear programming (MILP) model, which is solved by the column-and-constraint generation (CC&amp;G) algorithm. Finally, a real steel production system is given in a case study. Case study illustrate that compared with the traditional robust method, the method proposed in this paper for a SPIES can effectively reduce the conservatism of the scheduling decision. Numerical simulation show that the proposed method can reduce total cost by 55,307.1¥, accounting for 1.91% of the total cost compared with robust optimization method and save 1,326.94 s of computational time compared with the stochastic optimization method, thus reaching balance between conservatism and computational efficiency.