bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experience in implementing workplace wellbeing programs in Russia: results of a survey of employers on the ATRIA platform
Authors: Antsiferova A. A. , Kontsevaya A. V. , Khudyakov M. B. , Ipatov P. V. , Drapkina O. M. 
Published: July 2022

One of the effective approaches to the prevention of noncommunicable diseases and the extension of labor potential is the introduction of workplace wellbeing programs (WWPs). The implementation of WWPs and the formation of health promotion working conditions contribute to improvement of the wellbeing and quality of life of employees, reduce presenteeism, absenteeism and improve the economic performance of the company.Aim. To assess the experience of implementing the WWPs among employers in Russia using the ATRIA electronic platform.Material and methods. Experts from the National Medical Research Center for Therapy and Preventive Medicine have developed a set of tools (a questionnaire for employers and employees) to assist in the development and implementation of WWPs. A link to an ATRIA electronic platform was sent to the chief external specialists in preventive medicine to ensure a wide coverage of the country’s population. The survey was conducted from April 2020 to October 2021.Results. The survey involved 181 employers and 7500 employees (women, 63,2%, n=4735), but not every respondent answered all questions. The companies related to education, science and culture (23,8%, n=43), metallurgy/mining (19,9%, n=36) and chemical/ petrochemical industry (11,6%, n=21). The majority of employers (73%; n=73) consider it necessary to develop and implement WWPs, while the majority of them (66,9%, n=121) were not familiar with such programs. Companies mainly implement health examinations (79,4%, n=100), vaccination (78,6%, n=99), measures aimed at increasing the physical activity (73,8%, n=93). Only 50% of employers evaluate the effectiveness of WWPs: according to a survey of employees — 41,2% (n=47), according to temporary disability rate — 27,2% (n=31), according to staff turnover — 13,2% (n=15). Through the implementation of the WWPs, employers expect to improve employee health (94,4%, n=171), employee satisfaction (81,2%, n=147), morale (77,3%, n=140) and workforce productivity (75,1%, n=136).Conclusion. The prevalence of WWPs in Russia varies depending on the industry, the entities involved in its implementation, the nature of work and the number of employees, which creates health inequalities and justifies the need to develop targeted interventions and measures to implement WWPs.
Development and approbation of a tool for assessing municipal infrastructure affecting behavioral risk factors for cardiovascular and other noncommunicable diseases
Authors: Popovich M. V. , Kontsevaya A. V. , Zinovieva V. A. , Glukhovskaya S. V. , Savchuk A. N. , Mukaneeva D. K. , Antsiferova A. A. , Usova Е. V. , Drapkina O. M. 
Published: July 2022

Aim. To present first results of the study on the assessment of municipal infrastructure using specialized software in a pilot subject of the Russian Federation (Sverdlovsk Oblast).Material and methods. The following infrastructure elements of four municipalities of the Sverdlovsk Oblast have been assessed in the period from January to March 2022: sports facilities, grocery stores, fairs/markets with fresh vegetables and fruits, alcoholic drinks in shops and supermarkets, special liquor stores, tobacco outlets, fast food restaurants). The assessment was made with specialized software developed using Open Street Map (OSM) that allows real-time recording of objects for interactive map data visualization.Results. The density of sales outlets for tobacco, alcohol, fresh vegetables and fruits was 2,3, 3,4 and 2,4 per 1 km², respectively; the density of sports facilities, fast food and restaurants — 1,3, 0,9 and 0,5, respectively. The number of sales outlets for tobacco, alcohol, fresh vegetables and fruits per 100 thousand people was 111,6, 167,7 and 116,5, respectively, while the number of sports facilities, fast food and restaurants — 63,5, 44,1, 25,0, respectively.Conclusion. Creation and implementation of integrated system for assessing a unified preventive environment for promoting health and maintaining a healthy lifestyle at the municipal level using a combination of objective (GIS technologies, paraclinical tests) and subjective assessment methods (personal survey), as well as the introduction of interactive maps of municipal infrastructure, will make possible use of evidence to make decisions on the development and implementation of programs for the prevention of cardiovascular diseases and health promotion, as well as their management at the regional/municipal level.
Mortality from acute types of coronary artery disease in men and women in Russia in 2015 and 2019
Authors: Samorodskaya I. V. , Bubnova M. G. , Akulova O. A. , Matveeva I. F. 
Published: July 2022

Aim. To comparison standardized mortality rates (SMRs) among men and women from acute types of coronary artery disease (CAD) and their regional variability in Russia in 2015 and 2019.Material and methods. The Federal State Statistics Service (Rosstat) data on the population and the number of deaths from CAD based on the brief nomenclature of death causes using the Tenth Revision of the International Statistical Classification of Diseases and Related Health Problems (ICD-10) in 2015 and 2019 in 82 Russian subjects are presented. For each sex, SMR was calculated for acute (primary) and recurrent myocardial infarction (MI) (I21-I22), for other types of acute CAD (I20, I24.1-9), as well as average regional SMRs, coefficient of variation (CV).Results. The average regional SMR for each of the acute CAD types among men was significantly higher than among women both in 2015 (p<0,0001) and in 2019 (p<0,0001). For the period of 2015-2019 in men, SMR from all acute CAD types decreased by 22,5%, from acute MI — by 7,4%, from recurrent MI — by 22,2% and from other acute CAD types — by 25,8%, while in women, these figures were 11,8, 8,8, 19,0 and 29,7%, respectively. The men-to-women SMR ratio in 2015 and 2019 were 2,79/2,72 for all acute CAD types, 2,58/2,55 for all MI cases, and 3,36/4,18 for other acute CAD types. The minimum CV values (41,9% among men in 2019 and 44,7% among women in 2015) were recorded for acute MI, while the maximum CV values (129,3% among men and 158,6% among women in 2019) for other acute CAD types.Conclusion. Over the period of 2015-2019, the average regional SMR from acute CAD types in men and women decreased in Russia, with a more noticeable decrease for men. Greater regional variability in mortality, especially for other acute CAD types, poses the problem of finding organizational, methodological and strategic solutions to clarify the criteria for coding and refine the logistics schemes for providing healthcare for doubtful or uncertain diagnostic signs of acute CAD.
Brazilian and international nursing have a key role for combating racial exclusion and health inequities
Authors: Cruz Isabel Cristina Fonseca da 
Published: July 2022

Afro-descendant an indigenous populations have systematically over 500 years lagged behind the white population includding health issues.This secular process of exploitation lead to inequity and exclusion. It is necessary a clear understanding of the racism as a subtle social ideology of discrimination for designing and implement effective programs and policies that promote development with justice or in other words affirmative actions.Even the World Bank recognize that nurses can provide the majority of the care in clinical and health public services. But although our mission is based on humanistic principles, we have to point out the human rights to advocate for ethnic groups that are underserved or not have access to health.The reports of WHO and PAHO note the necessity of including the ONU´s report of Durbam´s Conference against Racism (August 2001) in the agenda of each health instituition. Particularly inLatin Americaand Caribe, we nurses must plan our actions with the main objectives of reduce and eliminate health disparities related mainly to racial an gender discrimination considering the cultural and ethnic aspects of our populations to provide culturally sensitive care.At the last number of the OBJN, I claimed to all nurses to show to the world wide what we have done, what we are doing, and our potencial skills to improve health and care for the population (CRUZ, 2002). Now, the OBJN claim to all nurses worldwide to contribute to the overall WHO/PAHO efforts and to do as much as possible to reduce an eliminate health disparities related to racial and gender discrimination.
The implementation of the nursing process methodology: problems and perspectives
Authors: Cruz Isabel Cristina Fonseca da 
Published: July 2022

The adherence to an international taxonomy of the nursing practice probably will be positively related to the implementation of the nursing process in the practice setting. This paper relates a dialectic analysis for identifying problems and perspectives related to the utilization of nursing diagnoses, nursing interventions, and client outcomes. Twelve nurses were interviewed and based on the data it was concluded that an ideological discourse about nursing activities is the principal obstacle to their development although the international and national political context are favorable implementation of the nursing activities.
Health and african-brazilian ethnicity research group (HABERG)
Authors: Cruz Isabel Cristina Fonseca da 
Published: July 2022

Since 1994, the Health and African-Brazilian Ethnicity Research Group is focused on the social determinants of health inequalities. The group was created and is directed by Isabel Cruz, RN, PhD It is based in the Medical-Surgical Nursing Department, Fluminense Federal University (RJ, Brazil). Its aims were to undertake multi-disciplinary social and health science research to advance the understanding of the social processes, particularly the racism, which underlie and mediate socio-economic inequalities in health and to advance the methodology of health inequalities research.These aims are been taking forward through two projects. The project related to the nursing diagnosis chronic low self-esteem and the nursing intervention cultural brokerage is multi-disciplinary, involving collaborators from arts (music, dance, painting, literature), economics, history, psychology, social policy and sociology. The other project is related to the nursing diagnoses and interventions to the hypertensive client and his family. Both projects have a focus on racism and socio-economic inequalities in health, addressing for example ethnic and gender inequalities which are not yet on the scientific and policy agenda of public health.Communication with the users of research has been a priority for the HABERG, which was linked regularly to over 500 users in and beyond Brazil by the NEPAE-NESEN Eletronic Newsletter which provides updates on HABERG activities, researches, and its policy implications. The information on the website (www.uff.br/nepae/NESEN.htm) provides a record of the research group activities.Publications: all HABERG newsletter articles and research reports are displayed on the website www.uff.br/nepae or www.uff.br/nepae/NESEN.htm
Urine-lipoarabinomannan-might fill the gap in delayed diagnosis of life-threatening tuberculosis
Authors: Kant Surya , Kumar Ankit , Niranjan Vijeta , Bajaj Darshan Kumar , Devi Laxmi 
Published: July 2022

Mycobacterium tuberculosis bacilli is a causative organism for tuberculosis disease. The lungs are the most commonly affected organ with this infection but it can infect any vital organ of the body. The person with signs and symptoms of tuberculosis disease was identified with detection of acid-fast bacilli in the biological specimen and with rapid molecular testing. However, the limiting factor for the early tuberculosis (Tb) diagnosis is the running cost of the diagnostic test. It is the common reason preventing the advancement of diagnostic laboratories in low and middle-income countries. The person and community both suffered from this diagnostic delay. This delay causes significant morbidity and mortality in the patient. An alternate test and an alternate sample that can be easily obtained would be beneficial to prevent these diagnostic delay issues. Lipoarabinomannan (LAM) antigen detection in the urine sample is one such promising diagnostic test. Mycobacterium tuberculosis’s inner layer is made up of glycolipids. LAM is derived from phosphatidylinositol. LAM is a heat-stable amphiphilic cell wall component. It is the precursor of phosphatidyl-inositol-mannosidase and lipomannan. An extra mannose cap is a characteristic feature of a virulent strain of Mycobacterium. LAM has immunogenic and immunomodulatory properties. It is a promising diagnostic test because it is simple to do, the assay can be performed at the patient’s bedside and takes a while to perform. This assay sensitivity varies from 56% to 85% and it has greater than 88% specificity. In HIV seropositive patients, use of LAM assay can reduce 8-week mortality. LAM detection is also a very good assay for the detection of tuberculosis in renal failure and disseminated tuberculosis patients.Lipoarabinomannan detection in the urine is a possible test that can prevent delay in diagnosis. This is a promising test because it's easy to perform, the test can be done with a card test besides the patient's bed. It can be used in HIV seropositive patients and various other forms of extra pulmonary tuberculosis. It can be a very useful test for diagnosing a critically ill patient who is not able to produce a target sample.
Molecular systems processes and cellular mechanisms-causing to itching tingling and aching in atopic dermatitis skin conditions and repercussions for innovative therapeutics
Authors: Raju V Rama 
Published: July 2022

: Atopic dermatitis (AD) is a prolonged seditious, rabble rousing, and inflammatory—provocative skin disease. The subjects (i.e., patients) by means of atopic-dermatitis suffer incendiary lesions linked through extreme itching plus discomfort, and that is leading to sleep disorder (and also rarely apnea), weak mental and psychological health and also quality-of-life (QoL). : This study discusses the molecular systems processes/mechanisms causing to itching, tingling and irritation plus aching signs in atopic-dermatitis and examine the existing clinical, medical-advancement of therapies for mild-to-acute atopic-dermatitis. : The molecular pathology of AD contains abnormal immune, protected stimulation including substantial crisscross-talk amongst the skin and safe and neural cells/neuronal cells. Exogenous and endogenous triggers modulate stimulus of mediators including cytokine/chemokine expression/release by the skin and immune cells, which causes inflammation, skin barrier disruption, activation and growth of sensory neurons, itching and paining. These complex interactions among cell types are mediated primarily by cytokines, but also involve chemokines, neurotransmitters, lipids, proteases, antimicrobial peptides, and agonists of ion channels or various G protein–coupled receptors. : Patients with atopic dermatitis have a cytokine profile characterized by abnormal levels of interleukins 4,12,13,18,22,31 and 33; thymic stromal lymphopoietin; and interferon gamma. Cytokine receptors mainly signal through the Janus kinase/signal transducer and activator of transcription pathways. Among emerging novel therapeutics, several Janus kinase inhibitors are being developed for topical or (general nut systemic) systematic treatment of mild to acute AD tis as of their ability to regulate-cytokine countenance then make available. Janus-kinase hampers take the lead to variations in genetic representation which has positive impacts on provincial and general (universal) cytokine-release, and possibly additional intermediaries, so well regulating molecular-cellular-mechanisms accountable for irritation, itching, tingling followed by agony in AD. : This study explored the skin disorder in which the skin develops pink, inflamed plus wound.
Evaluation of CD4 count response in HIV subjects with antiretroviral treatment protocol
Authors: Patel Kalpesh , Patel Varun , Samnani Simran 
Published: July 2022

The present study was undertaken to evaluate the CD4 count responses in subjects who are on long term first line antiretroviral treatment (ART).A total of 200 People Living with HIV/AIDS (PLHIV), on first line ART for five years seen in the ART centre were included in the study. Patients were interviewed and details entered as per the proforma. Proforma included various details such as serial CD4 counts and Opportunistic infection pre and post ART.Mean CD4 count pre ART was 171.32 ± 65.23 per mm and one year after ART was 374.56 ± 159.12. There was significant rise in CD4 count one year after the initiation of ART (p = 0.000) The mean CD4 count at the time of collection of data was 545.23 ± 259.11 as compared to mean CD4 count pre ART of 171.32 ± 65.23 per mm. The rise was significant.National AIDS Control. OrganizationNACO) suggested first line regimens outcome in vigorous immunologic response that is continued over a mean period of over six years in a majority (84%) of the subjects and consequence in significant decline in opportunistic infections.
Therapeutic effectiveness of bacteriophage in the treatment of pneumonia caused by NDM-4 producing in a mouse model
Authors: C.S VinodKumar , H Srinivasa , Kumar Chirag Arun , Kalasuramath Suneeta , Prasad B.S , V.L Jayasimha , Nachimuthu Ramesh , Manohar Prasanth 
Published: July 2022

Exploration for an alternative to antibiotics to treat bacterial diseases is becoming more important due to the emergence of antibiotic resistance. Bacteriophage or phage has been used for the treatment of superficial infections. In this study, phage isolated from the environment was used as a therapeutic agent against NDM-producing causing respiratory disease in an experimental mouse model. The isolated phage was found to belong to the family based on morphology. For experiments, five groups of mice were used including infection-free, phage-only, bacteria-infected, and the other two groups infected with and treated either with an antibiotic, levofloxacin (50 mg/kg, twice a day intraperitoneally) or phage (3×10 PFU/mL). All the animals were observed for 72 hours for mortality, and the surviving mice were killed for analysis. In the infected group, pneumonia was developed after 48 hours, and 8/10 animals were dead after 72 hours. When pneumonia infected mice were treated with an antibiotic, levofloxacin all the animals survived but showed the signs of pneumonia, and there was up to 6 log CFU/g±0.82 reduction in the bacterial count. In phage treated group, all the animals survived at the end of 72 hours and all the animals were healthy with no signs of pneumonia. The experiment showed new insights into the biology of the broad host range of phage, demonstrating that phage has prospects for the treatment of pneumonia caused by the NDM-producing .
Jornada de Estudos para Educação Onlife: um Relato de Experiência
Authors: Forneck Kári Lúcia , Fiorese Lucimara , Benini Érika Luíse 
Published: July 2022

A educação em tempos contemporâneos vem requerendo dos professores adaptações, considerando a inserção de Tecnologias Digitais (TD) em suas práticas de ensino. Para isso, é importante oportunizar contextos de formação continuada de professores para o uso de TD em sala de aula. Considerando esse cenário, o presente estudo relata a experiência de uma jornada de estudos acerca do uso de Tecnologias Digitais, para o desenvolvimento da educação onLIFE e do letramento digital. Assim, num primeiro momento, apresenta-se a execução da Jornada de Estudos: Ensino, Linguagens e Tecnologias, desenvolvida para discutir temáticas relevantes ao uso de TD em contextos de aulas remotas; num segundo momento, são apresentadas percepções dos professores participantes acerca da experiência formativa, obtidas por meio de formulários online. O conteúdo das respostas foi analisado a partir de uma aproximação com a Análise Textual Discursiva, em que emergiram três categorias: “a formação continuada e os desafios da tecnologia”, “vivemos em tempos de conexão?!” e “a prática docente em tempos de hiperconexão: leitura e escrita em ambientes digitais”. Como resultados, podem ser destacadas a) a necessidade de aprofundar discussões sobre a presença ou ausência de Tecnologias Digitais em sala de aula, b) a importância de oportunizar formações continuadas conectadas com as Tecnologias Digitais; e c) o uso de tecnologias em sala de aula, como percepção da educação onLIFE, que se dá por meio de plataformas, recursos e ferramentas digitais que são percebidas pelos docentes como contribuições de aulas hiperconectadas que promovem letramento digital.

Palavras-chave: Educação onLIFE. Formação continuada. Letramento digital. Tecnologias digitais.
The Role of Scintigraphy and Hybrid Single-Photon Emission Tomography in Comparison with Laboratory Data in a Comprehensive Examination of Patients with Secondary Hyperparathyroidism
Authors: Prokina V. Е. , Ansheles А. А. , Tarasov A. V. , Ametov A. S. , Sergienko V. B. 
Published: July 2022

Objective:to estimate the possibilities and determine the diagnostic value of scintigraphy and single-photon emission computed tomography combined with computed tomography (SPECT/CT) in the assessment of the functional state of parathyroids in comparison with laboratory data in patients with secondary hyperparathyroidism (SHPT). Material and methods.The study consistently included 64 patients with the established diagnosis of SHPT due to the acquired vitamin D deficiency or with terminal chronic kidney disease (CKD), with the presence of ultrasound data and laboratory tests of calcium-phosphoric exchange indicators. Neck and mediastum nuclear study with 99mTc-methoxy-isobutyl-isonitrile (MIBI) was performed in the planar two-phase scintigraphy mode according to the standard protocol with an estimation of parathyroid visualization intensity, as well as in SPECT/CT performed 1 hour after MIBI injection. Results. In the group of patients with CKD as a cause of SHPT (n = 14), the most pronounced increase of parathyroid hormone (PTH) level (210.8 ± 103.0 vs. 107.0 ± 40.2 pg/ml in patients with vitamin D deficiency (n = 50, p < 0.001)) and phosphorus (mean 1.39 ± 0.51 mmol/l), as well as excess of normal levels of alkaline phosphatase (407.7 ± 338.1 units/l) were noted. In patients with vitamin D deficiency, impaired parathyroids according to SPECT/CT data was visualized in 8 % of cases, and in patients with CKD in 14.3 %. No significant differences in the mean levels of vitamin D in patients with (n = 46) and without (n = 4) modified parathyroids according to scintigraphy were detected: 26.06 ± 13.19 vs. 25.82 ± 18.80 ng/ml, respectively (p = 0.97). Differences in PTH and calcium levels were not observed: 91.3 ± 39.2 vs. 89.2 ± 29.5 pg/ml (p = 0.90), 2.53 ± 0.21 vs. 2.58 ± 0,15 mmol/l (p = 0.64), respectively. Conclusion.The neck SPECT/CT is a key method of topical imaging of impaired parathyroids in preoperative preparation of patients with SHPT caused by CKD. The method may have a diagnostic value in treatment-resistant patients with vitamin D deficiency and upper-normal PTH and calcium levels in terms of detection of the nodular form of parathyroid hyperplasia. The implementation of SPECT/CT after 1 hour after MIBI injection increases the sensitivity of the study.