bluuebunny/crossref_metadata_2025_split huggingface dataset:
Indeterminate (B3) breast lesions: experience with vacuum-assisted biopsy under ultrasound guidance
Authors: Busko E. A. , Mortada V. V. , Krivorotko P. V. , Semiglazov V. F. , Pesotsky R. S. , Emelyanov А. S. , Amirov N. S. , Channov V. S. , Tabagua T. T. , Gigolaeva L. P. , Yerechshenko S. S. , Komyakhov A. V. , Nikolaev K. S. , Zernov K. Y. , Zhiltsova E. K. , Bondarchuk Ya. I. , Enaldieva D. A.. , Novikov S. N. , Apollonova V. S. , Tseluiko A. I. , Kasparov B. S. 
Published: October 2022

INTRODUCTION: Introduction of breast cancer screening programs has led to an increase in detection of non-palpable masses requiring core needle biopsy. Masses that fall into B3 category based on the histological results of core biopsy specimens, are of interest precisely because of their uncertain malignant potential and the lack of a final consensus on their management.OBJECTIVE: To analyze the 3-year experience of ultrasound guided vacuum-assisted biopsy (VAB) in patients with B3 breast lesions based on the results of histological examination of core biopsy specimens.MATERIALS AND METHODS: Between June 2019 and June 2022, 163 VABs were performed. The study group included patients with category 2–4 breast lesions according to the BI-RADS scoring system. The decision to perform VAB was made by the oncologist in each specific case on the basis of anamnesis, clinical data and the results of core biopsy histological examination: in cases of B3 or B2 lesions with a discordant radiologic pattern.RESULTS: In 155 (95.0%) cases, the removed lesions were benign, invasive cancer was detected in 2 (1.2%) cases, ductal cancer in situ in 6 cases (3.8%). The сomplications included: in 5 (3.1%) cases, patients had pain after the procedure, and in 37 (22.7%) cases there was a hematoma. In 5 (3.1%) patients, residual tissue was found at the site of removed lesions. CONCLUSIONS: VAB is a safe alternative to exploratory surgery in patients with B3 lesions diagnosed by core biopsy.
Pelatihan Penulisan dan Publikasi Artikel Ilmiah bagi Guru-Guru Sekolah Dasar
Authors: Widiana I Wayan , Tristiantari Ni Ketut Desia , Rediani Ni Nyoman , Yudiana Kadek Edi , Sari Ni Made Daini Vitri Sinta 
Published: October 2022

Guru-guru sekolah dasar masih mengalami banyak hambatan dan kendala dalam penulisan karya ilmiah serta publikais ilmiah diperlukan sebagai syarat kenaikan pangkat. Pengabdian ini bertujuan untuk memberikan pemahaman guru tentang teknik penulisan karya ilmiah dan tentang cara dan sistematikan publikasi ilmiah. Metode yang digunakan adalah In Service Training melalui metode ceramah, diskusi, presentasi, dan On Service Training melalui pendampingan melakukan perencanaan penelitian; melakukan progress report; menulis artikel ilmiah; dan pendampingan melakukan submit jurnal. Hasil dari pengabdian ini adalah peserta mampu memahami konsep artikel ilmiah dan dapat membuat artikel ilmiah yang siap publish pada jurnal-jurnal nasional terakreditasi. Kegiatan ini dikatakan berhasil karena pemahaman peserta terkait materi meningkat, respon peserta terhadap kegiatan ini sangat positif, dan terdapat salah satu guru yang mampu menulis artikel ilmiah dan siap publish di salah satu jurnal nasional terakreditasi.
Clinical outcomes of predoctoral implant dentistry education: A Systematic Review.
Authors: Nagpal Disha , Flores-Mir Carlos , Nassar Usama , Levin Liran 
Published: October 2022

AbstractObjectives: To systematically synthesize the status of predoctoral implant dental education in terms of clinical outcomes including implant success and survival of them when placed by predoctoral students.Materials and methods: A thorough search was carried out up to February 2019 using Medline (OVID), EMBASE, ERIC, and Web of Science electronic databases. In addition to this, bibliographies of the potentially eligible articles were searched manually. Abstracts that seemed to satisfy the initial selection criteria were selected for the recovery of the full text. The full-text risk of bias assessment was then done, in line with the selection criteria by two reviewers. The selected articles were evaluated using the Joanna Briggs Institute (JBI) Critical Appraisal tools. The GRADE approach was adapted, but not validated, for observational studies to assess the certainty of evidence.Results: Overall, 15 articles were included. Most of the reported implants were used to support mandibular overdentures or single unit implants and their survival rates were found to be generally favorable. Only a few studies also used patient satisfaction surveys which displayed overall satisfaction, suggesting that the dental implant treatment may be adequately provided in school settings.Clinical significance: The success and survival of the implant’s type done in an undergraduate classroom setting is indicative of the undergraduate dental implant curriculum. Based on this work, it can be concluded that the success and survival of such implants appear to be reasonable and most of the patients getting an implant at the school were satisfied.
The Microbially Extended Phenotype of Plants, a Keystone against Abiotic Stress
Authors: Ruiz-González Mario X. , Vicente Oscar 
Published: October 2022

Abstract

Background: Climate change affects every region across the globe with heterogeneous effects on local temperatures and precipitation patterns. In plants, sessile organisms, climate change imposes more drastic effects leading to loss of yield or even death. However, plants establish mutualistic interactions with microorganisms that boost plant tolerance against abiotic stresses or strengthen the plant immune system against pathogens, thus, enhancing their survival and fitness. Moreover, in the wild, microbial endophytes provide important ecosystem services.

Purpose and scope: Little we know about the mechanisms of response against the adverse effects of climate change on natural populations of wild plants and even less about the potential role played by microbial biostimulants. In this article, we review the effects of biostimulants on plant responses against abiotic stresses, with a particular focus on the role of mycorrhizas and leaf endophytes.

Results: We have reviewed the effects of the main abiotic stresses in plants, the mechanisms that plants use to face these abiotic challenges, and the interaction plant-biostimulant-abiotic stress, highlighting the primary responses and parameters to evaluate different plant responses.

Conclusion: Abiotic stresses can check the phenotypic plasticity of plants and also trigger a complex and heterogeneous array of responses to face different abiotic stresses, and beneficial microorganisms do play an essential role in enhancing such responses. Our laboratory has initiated a project to characterise microbial populations associated with plants from wild areas and analyse their potential role in aiding the plants to cope with abiotic stresses.
Influence of intercultural competence on an organisation’s success and personal career: the case study of Lithuania
Authors: Adamoniene Ruta , Blašková Martina , Petrauskiene Ruta , Rauleckas Rimantas 
Published: October 2022

Abstract
This paper aims to identify the influence of intercultural competence on an organisation’s success and personal career in Lithuania. The study described in this paper is a part of international research on intercultural competence. An online questionnaire survey was conducted in Lithuania with non-probability convenience sampling to find out the views of employees working in different sector organisations. The survey was filled out by 1193 respondents from Lithuania. Employees’ intercultural competence (knowledge/cognitive dimension, skills/behavioural dimension, and attitudes/emotional dimension) was evaluated using 5-point Likert items and is elaborated elsewhere. The multivariate analysis was used to analyse the survey data and test three hypotheses stating that (1) employees support the notion that higher intercultural competence can foster an organisation’s success and personal career, (2) organisations tend to leave the development of intercultural competence to employees, and (3) current intercultural knowledge and skills are inadequate to operate in a multicultural work environment. The analysis showed that half of the respondents agreed with the statement that the development of intercultural competence (ICC) helped the personal career and an organisation’s success. The statement regarding organisations tending to leave the intercultural competence development to their employees was only supported by less than one-third of the respondents. Besides, the data did not fully support the statement that employees’ current intercultural knowledge and skills were inadequate to operate in a multicultural work environment, as no more than one-third of the respondents had frequent or very frequent issues when communicating with foreigners due to inadequate intercultural knowledge and skills in various sub-areas. The paper elaborates on detailed results.
Collective creativity in management science
Authors: Ciachorowski Damian , Lis Anna Maria 
Published: October 2022

Abstract
This paper aims to establish the current state of knowledge on collective creativity in management science based on a systematic literature review. A systematic review was performed based on the three-step SPL procedure proposed by Tranfield et al. (2003). Two databases (Scopus and Web of Science) were searched electronically until March 2022. Literature analysis and content analysis were performed based on the secondary data. Eighteen studies met the inclusion criteria following the systematic literature review procedure. The conducted descriptive and thematic analysis allowed establishing the state of knowledge in the analysed area and identifying the main thematic areas along with the future research directions. The research was the first to conduct a systematic literature review (SLR) on collective creativity in management science. The main contribution of this paper is its exclusive focus on analysing existing research in the collective creativity field, limited to management science. SLR allowed determining that research in the analysed area was still at a fairly early stage. Although the existing literature sheds some light on collective creativity, studies investigating the aspects of teamwork focused on problem-solving are required.
Pathophysiological and clinical aspects of the circadian rhythm of arterial stiffness in diabetes mellitus: A minireview
Authors: Serhiyenko Victoria A. , Serhiyenko Ludmila M. , Sehin Volodymyr B. , Serhiyenko Alexandr A. 
Published: October 2022

Abstract
Several cross-sectional trials have revealed increased arterial stiffness connected with the cardiac autonomic neuropathy in types 2 and 1 diabetic patients. The pathophysiological relationship between arterial stiffness and autonomic dysfunction in diabetes mellitus is still underinvestigated and the question whether the presence of cardiac autonomic neuropathy leads to arterial stiffening or increased arterial stiffness induced autonomic nervous system impairment is still open. Both arterial stiffness and dysfunction of the autonomic nervous system have common pathogenetic pathways, counting state of the chronic hyperinsulinemia and hyperglycemia, increased formation of advanced glycation end products, activation of protein kinase C, development of endothelial dysfunction, and chronic low-grade inflammation. Baroreceptor dysfunction is thought to be one of the possible reasons for the arterial wall stiffening development and progression. On the contrary, violated autonomic nervous system function can affect the vascular tone and by this way alter the large arteries walls elastic properties. Another possible mechanism of attachment and/or development of arterial stiffness is the increased heart rate and autonomic dysfunction corresponding progression. This minireview analyzes the current state of the relationship between the diabetes mellitus and the arterial stiffness. Particular attention is paid to the analysis, interpretation, and application of the results obtained in patients with type 2 diabetes mellitus and diabetic cardiac autonomic neuropathy.
Manifestations of Sustainable Development in China: Based on Policy Study
Authors: Wu Yue , Zhong Xinzhi 
Published: October 2022

Abstract

Subject and purpose of work: This article aims to better understand China’s actions and challenges encountered in sustainable development due to the COVID-19 crisis, economic difficulties, and the war between Russia and Ukraine. It also aims to provide valuable recommendations for China or other countries concerning future sustainable development work.

Materials and methods: We reviewed extensive literature and made a policy content analysis as the research methodology.

Results: We concluded that China has put emphasis on sustainable development since ancient times. China has made notable progress in sustainable development both domestically inside China and worldwide. However, China also faces challenges related to sustainable development within China itself.

Conclusions: Although China has launched effective policies that have received positive feedback, there is still a long way to go to achieve truly sustainable development. We suggest that all countries, regions, and individuals take a joint action in order to achieve a sustainable planet for us and future generations.
The interrelation between otorhinolaryngology and orthodontics in solving malocclusion and facial dysmorphisms caused by chronic adenotonsillitis
Authors: Cobzeanu Bogdan Mihail , Palade Dragos Octavian , Bandol Gianina , Rusu Daniela , Severin Florentina , Rosu Andrei , Roman Andrei , Vlad Andreea , Mocanu Florin , Cobzeanu Mihail Dan , Cobzeanu Maria Luiza , Zetu Irina , Iacob Mihnea 
Published: October 2022

Abstract

OBJECTIVES. The aim of this study was to reevaluate the implication of early diagnosis of chronic adenoid syndrome and tonsillar hypertrophy in the prophylaxis and control of facial and dental deformities in children.

MATERIAL AND METHODS. The authors conducted a prospective study on 42 paediatric patients with chronic adenoid syndrome admitted in the ENT and Orthodontic Departments of “Sf. Spiridon” Emergency Hospital and “Sf. Maria” ENT Paediatric Department, Iasi, treated in collaboration with orthodontic and logopaedic specialists, with follow-up on the improvement of symptomatology and morphofunctional deficiencies.

RESULTS. Late diagnosis and treatment of the obstructive adenoid hypertrophy can cause difficulty in managing cases, consequently maintaining the aesthetic deficiencies and morphofunctional disorders within a follow-up period of 2 years. Furthermore, we present the chronic complications due to obstructive adenoid hypertrophy (rhinosinusal and ear-related diseases, obstructive sleep apnea), as well as the progression of these cases after interdisciplinary approach.

CONCLUSION. Chronic adenoiditis and tonsillar hypertrophy can increase the incidence of malocclusion in children, as well as causing changes in length and shape of the upper jaw and mandible, resulting in maxillofacial deformities.
Endothelial progenitor cell (EPCs)-derived exosomal miR-30d-5p inhibits the inflammatory response of high glucose-impaired fibroblasts by affecting the M1/M2 polarization of macrophages
Authors: Xiong Wu , Tan Mei-xin , Chen Zi-lin , Liu Yu , Liu Yang , Zou Xiao-ling , Wang Xiao-qin , Yang Ya , Tan Pei , Zhang Xi 
Published: October 2022

Abstract

Background: Diabetes is a common chronic disease which has caused a great burden on families and society. The treatment of diabetes has always been a hotspot. This study aimed to explore the effect and mechanism of miR-30d-5pon inflammation of high glucose-impaired human keloid fibroblasts (HKF).

Methods: Differently-expressed miRNAs were predicted by bioinformatics methods. Exosomes were observed by transmission electron microscope. Exosome particle sizes were measured by NanoSight. Western Blot was used to detect the expression of CD81, CD63, CD9, and Calnexin. QRT-PCR was used to detect the expression of miR-30d-5p, IL-1β, TNF-α, VEGF, FGF21, NRF2, and HO-1. The levels of IL-1β, TNF-α, IL-6, IL-10, and TGF-β were determined by ELISA. Cell apoptosis and CD86, CD206 positive cells were detected by flow cytometry.

Results: Tori formula could promote the secretion of endothelial progenitor cell (EPCs) exosomes. EPCs exosomes and miR-30d-5p could stimulate the proliferation of HKF impaired by high glucose and the expression of IL-10 and TGF-β. MiR-30d-5p inhibited the proliferation of M1 macrophages and the expression of IL-1β and TNF-α. It could also promote the proliferation of M2 macrophages and the expression of CCL17 and CCL22. Moreover, miR-30d-5p stimulated the expression of VEGF, FGF21, NRF2, and HO-1, as well as suppressed the expression of IL-1β, TNF-α, and IL-6. MiR-30d-5p also restrained the apoptosis of impaired HKF. Conclusion: This study confirmed that miR-30d-5p could promote the M1/M2 polarization and inhibit the inflammatory response of impaired HKF, which provided a certain idea and direction for treating diabetes.
Correlations of cofilin1 and phosphorylation at Ser3 site with sensitivity of elderly patients with non-small cell lung cancer to radiotherapy
Authors: Lu Feijie , Zhong Chunrong , Dong Yongquan , Wang Mingming , Yang Qi 
Published: October 2022

Abstract

Background: To explore the correlations of cofilin1 (CFL1) and phosphorylation level of locus serine residue at position 3 (Ser3) with the sensitivity of elderly patients with non-small cell lung cancer (NSCLC) to radiotherapy.

Methods: A total of 102 eligible patients treated from June 2013 to April 2015 were selected. The cases of complete remission and partial remission were included into radiotherapy-sensitive group (n=55), while those of stable disease and progressive disease were enrolled into radiotherapy-resistant group (n=47). Before treatment, tissues were collected to detect the expressions of CFL1 and CFL1 (phospho S3) by immunohistochemistry. The survival time and rate were recorded during follow-up.

Results: Compared with the radiotherapy-sensitive group, the radiotherapy-resistant group had advanced tumor-node-metastasis (TNM) stage and higher lymph node metastasis rate (P=0.000, 0.000). Compared with the tissues with negative CFL1 expression, the tissues with positive CFL1 expression had advanced TNM stage and higher lymph node metastasis rate (P=0.013, 0.000). The positive expression rate of CFL1 in the radiotherapy-resistant group was higher than that of the radiotherapy-sensitive group, whereas the positive expression rate of CFL1 (phospho S3) in the former was lower (P=0.000, 0.000). Lymph node metastasis, high CFL1 expression, and low CFL1 (phospho S3) expression were independent predictors for resistance to radiotherapy (P=0.001, 0.006, 0.003). In the radiotherapy-sensitive group, the patients with negative CFL1 expression and positive CFL1 (phospho S3) expression had long progression-free survival and high 5-year survival rate (P=0.000, 0.000).

Conclusion: The sensitivity to radiotherapy of elderly NSCLC patients is correlated negatively with CFL1 and positively with phosphorylation at locus Ser3. CFL1 and phosphorylation at locus Ser3 are independent predictors for sensitivity to radiotherapy.
Protocol and Matters for Consideration for the Treatment of Polymerase Chain Reaction Contamination in Next-Generation Sequencing Laboratories
Authors: Wang Lin , Ma Chen , He Bin , Qiang Rong , Zhang Hongsu 
Published: October 2022

Abstract

Objective: The contamination of polymerase chain reaction (PCR) samples in molecular diagnostic laboratories can cause serious consequences. Internal quality control efforts are often inadequate, especially in clinical next-generation sequencing (NGS) laboratories.

Methods: In this study, we retrospectively investigated an incidence of PCR contamination and its decontamination process in a clinical laboratory. We performed a series of measures for decontamination. Taqman fluorescence quantification was carried out to determine the presence of contaminating DNA. SYBR-Green PCR was conducted to evaluate the effect of chlorine disinfectant on NGS library preparation.

Results: Through a series of elimination measures undertaken over 8 weeks, the decontamination process was verified as reliable. Almost no contamination was detected. Chlorine disinfectant should be forbidden in Illumina NGS laboratories because it may cause the failure of library preparation.

Conclusion: Our prevention and decontamination strategies could effectively eliminate PCR amplicons. Chlorine disinfectants should not be used in Illumina NGS laboratories.
التحليل المكاني للحوادث المرورية في مدينة سامراء لعام 2020
Authors: Saleh Ahmed Omar Mohamed 
Published: October 2022

منذ زمن بعيد أصبحت الحوادث المرورية والإصابات الناتجة عنها تشكل هاجسا مقلقا لجميع فئات المجتمع كونها متصلة بأحد الأنشطة اليومية المهمة التي لم يعد بالإمكان الاستغناء عنها إلا وهي استخدام المركبات في حركة النقل والتنقل، فعلى الرغم مما أتاحته المركبات للأفراد من مميزات كبيرة كاختصار الوقت وطي المسافات وتواصل الجماعات البشرية المتباعدة فيما بينها وتنظيم حياة الناس، فضلا عن حمايتهم من تقلبات المناخ وأحوال الطقس المختلفة ، ألا إن استخدامها في الفترة الأخيرة بات محفوفاً بالعديد من المخاطر ، وهذا استدعى القيام بدراسة هذه الظاهرة وبيان اسبابها وتكرار حدوثها وتحديد أهم النقاط أو الاماكن التي تحدث فيها الحوادث المرورية ومحاولة ايجاد الحلول الملائمة للحد من وقوع هذه الظاهرة ضمن الحدود الادارية لمدينة سامراء , فمن خلال الدراسة والتحليل تبين ان هناك تباين في نسبة وقوع الحوادث المرورية ونوعيتها من حيث الاصطدام والدهس والانقلاب وحجم الخسائر البشرية والمادية الناتجة عنها وذلك بحسب طبيعة الزخم السكاني و المروري .
اثر انموذج رحلة التدريس في تحصيل طلاب الصف الخامس العلمي في مادة التربية الاسلامية وتنمية تفكيرهم المستقبلي
Authors: Sahab Saadia M. 
Published: October 2022

هدف البحث التعرف على اثر انموذج رحلة التدريس في تحصيل طلاب الصف الخامس العلمي في مادة ‎التربية الاسلامية وتنمية تفكيرهم المستقبلي.
تم اختيار المنهج التجريبي ذو المجموعتين المتكافئة , طبق البحث في الفصل الدراسي الاول من العام الدراسي (۲۰۲۰-۲۰۲۱) م تكونت العينة من (60) طالبا بواقع (30) طالبا في كل من المجموعة التجريبية والضابطة .كوفئت المجموعتين بمتغيرات عدة واعدت الباحثة اغراضا سلوكية للمادة العلمية, وخططا تدريسية . وأعدت اداتين للبحث هما اختبارا تحصيليا تألف من(40) فقرة موضوعية ومقياسا للتفكير المستقبلي تكون من (40) فقرة بثلاثة بدائل وتم التحقق من صدقهما وخصائصهما السايكومترية كما تم أيجاد ثباتهما .بعد الانتهاء من تدريس المجموعتين وتطبيق الاختبارات البعدية تمت معالجة البيانات احصائيا وأظهرت نتائج البحث :
‎۱-وجود فرق ذو دلالة إحصائية بين متوسط درجات طلاب المجموعة التجريبية الذين درسوا وفقا لأنموذج رحلة التدريس ودرجـات طـلاب المجموعة الضابطة الذين درسوا وفقا للطريقة الاعتيادية في الاختبار التحصيلي ‎ومقياس التفكير المستقبلي لصالح متوسط المجموعة التجريبية.
۲-وجود فرق ذو دلالة إحصائية بين متوسطي درجات طلاب المجموعة التجريبية الذين درسوا وفقا لأنموذج رحلة التدريس قبل التجربة وبعدها في مقياس التفكير المستقبلي لصالح المتوسط البعدي .
‎وبناء على هذه النتائج وضعت الباحثة جملة من الاستنتاجات والتوصيات كما اقترحت أجراء دراسات مستقبلية .
تشخيص الطبيعة الحية في شعر الجواهري
Authors: Muhammed Farooq Abdul Salam , AbdAljabbar Sanaa Salman 
Published: October 2022

لقد كانت الطبيعة الحية من اهم بواعث الشعر عند الجواهري. فقد كانت عناصرها على اختلاف انواعها جزءً لا يتجزأ من حياة الناس عامة و الشاعر بشكل خاص, فكانت إحدى منابع التصوير الفني والتنسيق الجمالي التي يلجأ اليها الشاعر في كثير من الاحيان.
الشاعر ابن بيئته ولا يمكن له الانسلاخ منها, و الطبيعة الحية جزء من تلك البيئة المحيطة بالشاعر, و تشكل الحيوانات الركن الاهم فيها. فقد تناول الشعراء قديما و حديثا وصف الحيوانات بتفاصيلها كلها. و إذا ما نظرنا الى النصوص التي تناولت الطبيعة الحية, نجدها ساعدت على اكتمال ملامح النص و ساعدت في سد الفراغات ضمن الهيكل العام للقصيدة.