bluuebunny/crossref_metadata_2025_split huggingface dataset:
The length of distal skin incision of the postero-lateral approach affects the cup inclination during the total hip arthroplasty
Authors: ÇATALTEPE Aziz 
Published: September 2022

Aim: The primary aim of the study was to determine whether the length of the distal skin incision of the posterolateral approach affects the cup inclination during total hip arthroplasty (THA).
Material and Method: In this study, a cohort of 71 consecutive patients who performed between January 2017 and December 2021 with unilateral THA using a posterolateral approach was retrospectively assessed. Two groups were formed according to acetabular cup inclination with normal anteversion angle. There were 56 hips in the inside group and 17 in the outside group. A curvilinear skin incision of around 13 cm was performed. Component position evaluation was carried out through a radiographic assessment of the acetabular component on an anteroposterior pelvis radiograph. The rate of an outlier was compared between groups according to the safe zone defined as 30° to 50° of inclination and 5° to 25° of anteversion, which was described by Lewinnek et al.
Results: No significant difference in the average total incision length was found between the two groups (p=0.207). While the average distal incision length was 7.91±0.62 cm (range, 6.8-9 cm) in the inside group and 6.37±0.21 cm (range, 6-6.7 cm) in the outside group. According to ROC analysis, a patient with ≤6.7 cm of the distal length of incision (DLI) was 5.71 times more likely to be outside than a patient with >6.7 cm of DLI. Seventeen hips (23.3%) were found outside the safe range. Substantial differences were observed regarding radiographic cup inclination between the two groups (p=0.0001). In the inside group, the average cup inclination was 44.11°±3.44° (range, 37°-50°), whereas, in the outside group, it was 55.41°±2.5° (range, 52°-59°). However, there were no significant differences in the average radiographic cup anteversion between the two groups (p=0.960). Although 11 of 17 (64.5%) patients were classified as obese (BMI ≥30) in the outside group experienced higher rates of inaccurate cup orientation, logistic regression analysis showed that the individual effects of obesity on the occurrence of the inaccurate cup position were not observed (p=0.884). One posterior hip dislocation occurred after one month postoperative in the outside group.
Conclusions: Longer distal portion of the skin incision of the posterolateral approach should be performed to achieve optimal operative inclination angles of the acetabular cup during THA. The surgeon must have no hesitation in extending the distal skin incision when adopting the posterolateral approach.
Controversies in neonatology: The efficacy of inhaled nitric oxide in preterm infants with persistent pulmonary hypertension
Authors: VARDAR Gonca , AKSOY OKAN Meliha , TOPÇUOĞLU Sevilay , KARADAĞ Nilgün , ÖZALKAYA Elif , OZGUN KARATEPE Hande , KARATEKİN Güner 
Published: September 2022

Introduction: There is limited and conflicting information in literature regarding use of inhaled nitric oxide (iNO) in preterm infants. In this study we examined the characteristics of preterm infants with persistent pulmonary hypertension (PHT) who responded and did not respond to iNO therapy .
Material and Method: We retrospectively reviewed data of infants
The relationship of nailfold capillaroscopy patterns with clinical features, functional status, pain and fatigue in patients with systemic sclerosis
Authors: ERDEM GÜRSOY Didem , GEZER Halise Hande , ACER Sevtap , BAKLACIOĞLU Hatice Şule , DURUÖZ   Mehmet Tuncay 
Published: September 2022

Aim: To identify the frequency of scleroderma-type capillaroscopic patterns and evaluate the association of capillaroscopic patterns with clinical parameters, functional status, fatigue, and pain in systemic sclerosis (SSc).
Material and Method: This cross-sectional study included SSc patients consecutively between January 2017 and January 2019. Cutaneous involvement was evaluated with the modified Rodnan skin score (mRSS). The presence of digital ulcers, Raynaud phenomenon, interstitial lung disease, pulmonary hypertension, cardiac, gastrointestinal system (GIS), renal, joint and muscle involvement were recorded. The severity of the Raynaud phenomenon, fatigue, pain, and patient global assessment (PGA) was assessed on the Visual Analogue Scale (VAS). The Health Assessment Questionnaire (HAQ) and the Duruoz Hand Index (DHI) were used to assess physical disability and hand function, respectively. Nailfold videocapillaroscopic examinations of the patients were performed, and they were classified into four groups, including normal/non-specific, early, active, and late scleroderma patterns.
Results: The mean age of 32 patients with SSc (31 female, one male) was 48.93±12.77. Anormal capillaroscopic examination findings were detected in 93.7% of the patients, and the most common capillaroscopic pattern was the active pattern. The comparison of scleroderma pattern groups revealed no difference in age (p=0.224), but disease duration was shorter in the early pattern group (p=0.005). The duration and severity of the Raynaud phenomenon, and mean mRSS were lower in the early pattern group (p=0.004, p=0.009, and p=0.001, respectively). The digital ulcer (p=0.011) and diffuse cutaneous SSc (p=0.016) were more common in the late pattern group. The percentage of pulmonary hypertension (p=0.011), GIS involvement (p
Does uterine septum resection improve IVF treatment success?
Authors: CEVHER AKDULUM Munire Funda , DEMİRDAĞ Erhan , ARIK Seçil İrem , ERDEM Mehmet , BOZKURT Nuray , OKTEM Mesut , GÜLER İsmail , ERDEM Ahmet 
Published: September 2022

Aim: Uterine septum is the most common type of congenital uterine malformation. The septum has also been suggested as a potential cause of infertility. The role of the septum in infertility and whether the septum can be resected is debatable. We aimed to reveal the results of assisted reproductive techniques in patients with septate uterus according to whether or not resection is performed.
Material and Method: 7790 patients were scanned retrospectively. 110 patients with the uterine septum and unexplained infertility were included in the study. Patients who underwent uterine septum resection were recorded. The clinical pregnancies of patients were compared according to whether or not resection was performed. In addition, patients with complete septum were evaluated according to whether or not resection was performed, and their clinical pregnancies were evaluated.
Results: It was revealed that 79 of the patients with uterine septum underwent septum resection operation. It was determined that 31 patients were not treated. Clinical pregnancy rates were found to be statistically significantly higher in the expectant management group (p=0.02). In addition, comparing the clinical pregnancy rates of the resection and expectant management groups in patients with a complete septum, no significant difference was found between the groups (p=0.134).
Conclusion: In our study, the success of treatment with assisted reproductive techniques did not change after septum resection. Although uterine septum resection is a simple and safe method, it has disadvantages such as the development of adhesions and rupture in the uterus. There is insufficient evidence to perform septum resection in patients with uterine septum prior to infertility treatment.
The effect of immunosuppressive therapy on the development of ventilator-associated pneumonia in patients with COVID-19
Authors: CANOĞLU Kadir , AYTEN Omer 
Published: September 2022

Aim: It remains unclear whether immunosuppressive treatments such as corticosteroids and IL-6 receptor blockers have an effect on the development of ventilator-associated pneumonia (VAP). The aim of this study was to investigate the effect of immunosuppressive therapy on the development of VAP in critically ill patients with COVID-19.
Material and Method: Two hundred thirty five patients with critically ill patients with COVID-19, who were treated in the intensive care unit (ICU) and received mechanical ventilator support, were evaluated retrospectively. VAP development, secondary infections, microorganisms isolated, and resistance patterns were compared between the groups that received and did not receive immunosuppressive therapy, and also the groups that did not receive immunosuppressive therapy, received only corticosteroid, received only tocilizumab, and received corticosteroid plus tocilizumab were compared in the subgroup analysis.
Results: In the immunosuppressive treatment group, VAP development (40.2% vs. 21.2%; p=0.001), secondary infection development (48.4% vs. 29.2%; p=0.003), at least one drug resistant bacteria growth (46.7% vs. 27.4%; p=0.001), extensively-drug resistant (XDR) microorganism growth (89.8% vs. 72.7%; p=0.033) were higher than the group that did not receive immunosuppressive treatment. VAP (53.3%; p=0.004), secondary infection (73.3%; p=0.0002), the growth of bacteria resistant to at least one drug (70%; p=0.0003) were highest in the corticosteroid plus tocilizumab group in the subgroup analysis. In addition, XDR (95.5% vs. 72.7%; p=0.032) and pan-drug resistant (PDR) microorganism growth (31.8% vs. 9.1% p=0.032) were higher in the corticosteroid plus tocilizumab group than the no immunosuppressive therapy group. There was no difference between the groups in terms of mortality (p>0.05).
Conclusion: Immunosuppressive therapy has been found to potentially enhance the risk of VAP and secondary infections in critically ill patients with COVID-19 pneumonia as well as the growth of bacteria resistant to at least one drug, the length of stay in hospital and ICUs. In addition, it has been evaluated that there may be an increase in the growth of XDR and PDR microorganisms when corticosteroid and tocilizumab are used together. Although there was no difference in mortality, using immunosuppressive therapy may require careful use of targeted antibiotics and longer-term antimicrobial therapy.
The progress of chronic renal disease patients followed by the diagnosis of COVID-19 in ICU
Authors: UYSAL Elmas , SEĞMEN Fatih , ULUBAŞOĞLU Pınar , ZENGİN Emine Nilgün , ERDEM Deniz 
Published: September 2022

Aim: The mortality and morbidity of COVID-19 disease are higher in patients with comorbidities. In this study, we staged patients with chronic renal failure hospitalized in the intensive care unit (ICU) and aimed to evaluate the process of the disease according to the stage of failure.
Material and Method: The medical records of 249 patients followed in Ankara City Hospital MH3 ICU were reviewed retrospectively. The patients were divided into three stages according to their estimated glomerular filtration rate (e-GFR) value (stage 1: e-GFR≥90 ml/min/1.73 m², stage-2: e-GFR: 15-89 ml/min/1.73 m², stage- 3: e-GFR≤15 ml/min/1.73 m²). Data such as age, gender, comorbidity status, length of stay in the ICU, duration of mechanical ventilation, and mortality rate of the patients were recorded. Patients who were evaluated as stage-2 were also classified into 3 stages (stage-2a: e-GFR: 60-89 ml/min/1.73 m², stage-2b: e-GFR:30-59 ml/min/1.73 m², stage-2c: e-GFR: 15-29 ml/min/1.73 m²) and evaluated with the same parameters.
Results: The mean age of all patients was 71 years. It was found that the intubation rate was higher (p=0.012) and the mortality rate was higher (p=0.003) in patients evaluated as stage-3. APACHE II and SOFA scores were higher than the other groups (p=
Development of Ecotourism for Local Economic Growth in Chotiari Wetland Complex-Sanghar, Sindh Pakistan
Authors: Nazir Humaira 
Published: September 2022

Tourist organizations, such asSindh Tourism Development Corporation (STDC), Sustainable Development Foundation (SDF), andWorldWide Fund for Nature-Pakistan (WWF-Pakistan), agree that ecotourism has a significant potential to invite both domestic and foreign visitors. Accordingly, ecotourism industry has been promoted as one of the most important tourist industries due to its potential for protecting natural resources, while also improving the socio-economic conditions of local residents. As per thereview of relevant literature, most of the developed and underdeveloped nations utilize their natural assets for tourism and economic upliftment. Thus, the study aimed at determining how ecotourism development adds to the economic growth of local communities of the study region. The research was carried out in Chotiari Wetland Complex,Sindh, Pakistan primarily due to its scenic natural assets. The research sample included officials of local non-governmental organizations (NGOs), local community organizations, the management of Chotiari's Nature Reserve, local leaders, and individuals from local households living inareas surrounding the wetland.A sample of 60 participants was chosen from the communityusing a random sampling methodology. Mixed-methods research, comprising both quantitative and qualitative methodologies,wasused to collect and analyzethe collected data, interpret results, and draw conclusions. A questionnaire survey was used as a toolto collect data. The Statistical Package for the Social Sciences (SPSS version 22) was utilized to evaluate quantitative records, while content interpretation was conductedtoevaluate qualitative information. The findings indicated that ecotourism and wetland developmentimprovedthe local economic growth of the studied region through jobcreation and capacity building.
Keywords: ecotourism,foreign visitors, local economic growth, natural resources, wetland development, WWF-Pakistan
Assessing the Potential of Sustainable Urban Regeneration in Lahore: A Case Study of Orange Line Metro Train Route
Authors: Rafique Saima , Nadeem Obaid-ullah , Asim Muhammad , Jalil Adnan 
Published: September 2022

Urban regeneration is viewed as a far-reaching field in urban planning. Urban regeneration contributes not just to set up new urban structures in urban communities, yet in moulding the urban communities as well. The long-term vision of urban regeneration projects along with transit corridors is to promote sustainable patterns of urban growth by ensuring all urban design features and creating higher densities along transit and non-motorized transit use. This research aims to assess the potential of urban regeneration along the route of Orange Line Metro Train. The primary data was gathered using in-depth interviews and structured questionnaires. All the 26 stations of Orange Line Metro train were divided into three equal stratums. Furthermore, the middle order station had been selected from all the three stratums and for each selected station a buffer was drawn of half of a kilometer radius and selected as a sample of the study area. Respondents were asked about their opinion regarding the significance level of the different urban design features of a sustainable urban regeneration project. The Cronbach’s alpha of the data collection instrument was calculated as 0.71, which is higher than the acceptable reliability coefficient. The validity test was completed by Principal component analysis. Varimax rotation was used for the rotation of components. KMO adequacy test was 0.707, which must be more than 0.5 to retain the variables, and the variables with Kaiser-Meyer-Olkin Measure less than 0.5 must be excluded from the study. Bartlett’ Test was significant at p<.05. The significance index of urban design features for sustainable urban regeneration projects had been calculated. Overall, the necessary attributes of sustainable urban regeneration project were found. The research provides the priority areas of urban regeneration as per the key stakeholders along the Orange Line Metro Train Route.
Keywords: Urban regeneration, Light Rail Transit (LRT), urban design features, mixed development, security against crimes, price premier
Lumpy Skin Disease: A Review
Authors: Raja Hasan , Khan Irfan , Madan Vani , Sharma Dr. Vandana , Sharma Dr. Mukesh , Lal Soni Shankar , Sharma Ashok Kumar 
Published: September 2022

In India, a newly emerging viral disease known as lumpy skin disease (LSD) affects cattle and buffalo. Arthropods (mosquitoes, biting flies, Culi-coides midges, and three blood-sucking hard ticks) that operate as mechanical vectors are the primary means of disease transmission. Skin nodules all over the body, fever, lacrimal discharge, nasal discharge, anorexia, decreased milk yield, emaciation, sadness, and unwillingness to move are some of the most significant clinical symptoms. Since the first discovery of lumpy skin disease in India, the condition has been swiftly spreading throughout the nation, posing a potential threat to the production and survival of the cow and buffalo populations.
Through the Middle East, lumpy skin disease of cattle (LSD) has since spread outside of Africa. It is now threatening to become a worldwide pandemic, with india possibly next in its path.
Pelatihan Pembuangan Masker Sebagai Upaya Pencegahan Penyakit Infeksi di Desa Sukowati Kecamatan Kapas Kabupaten Bojonegoro
Authors: Saputri Romadhiyana Kisno , Hutahaen Titi Agni , Ni'am Musfirotun , Albabi Nabila Ulul 
Published: September 2022

Pemakaian masker sekali pakai meningkat 30% -50% selama pandemi COVID-19. Sampah masker masuk ke dalam sampah infeksius atau sampah yang dapat menyebabkan penyakit infeksi, sehingga sebelum dibuang, perlu penanganan khusus yaitu didisinfeksi lalu dirusak masker dengan cara dilepas tali masker atau disobek. Sampah masker skala rumah tangga harus dikumpulkan tersendiri, digunting, direndam dengan larutan disinfektan dan dibungkus dengan kantong plastik sebelum dibuang. Kegiatan pengabdian kepada masyarakat ini bertujuan untuk meningkatkan pengetahuan dan keterampilan masyarakat dalam membuang masker sebagai upaya pencegahan penyakit infeksi. Metode yang digunakan pada kegiatan ini adalah metode ceramah dan simulasi atau praktik langsung di depan sasaran. Sasaran adalah ibu-ibu PKK yang berjumlah 40 orang. Kegiatan ini memberikan hasil adanya peningkatan tingkat pengetahuan mengenai pembuangan masker yang tepat sebesar 55% dan peningkatan keterampilan mengenai pembuangan masker yang tepat sebesar 87,5%. Kegiatan pengabdian kepada masyarakat ini mampu meningkatkan pengetahuan dan keterampilan masyarakat dalam membuang masker sebagai upaya pencegahan penyakit infeksi.
An Investigation of Backscatter Power Spectra from Cells, Cell Pellets and Microspheres
Authors: Kolios Michael , Taggart L. , Baddour Ralph E. , Foster F. S. , Hunt J. W. , Czarnota G. J. , Sherar Michael D. 
Published: September 2022

<p> It has been previously shown that high frequency ultrasound (20 - 100 MHz) can be used to detect cellular structure changes in tissues and cell ensembles. However, the changes seen in the backscattered ultrasound intensity and frequency spectrum are not fully understood. In this paper we attempt to better understand the nature of these changes by examination of the backscatter power spectra from cell ensembles (in pellet form) that have undergone two different types of cell death: by exposure to the chemotherapeutic cisplatin and by withdrawal of nutrients (decay). Three different ultrasound transducers were used, centered at 20MHz and 40MHz. In both death pathways, an increase of the midband fit of 10-12dB was measured, and there were significant changes in the spectral slopes. Furthermore, our initial analysis of the backscatter from single cells and polystyrene microspheres demonstrates the potential of the technique to assess scatterer size. </p>
Solving Exchange Rate Puzzles with neither Sticky Prices nor Trade Costs
Authors: Moore Michael J , Roche Maurice J 
Published: September 2022

<p>We present a simple framework in which both the exchange rates disconnect and forward bias puzzles are simultaneously resolved. The flexible-price two-country monetary model is extended to include a consumption externality with habit persistence. Habit persistence is modeled using Campbell Cochrane preferences with „deep‟ habits. By deep habits, we mean habits defined over goods rather than countries. The model is simulated using the artificial economy methodology. It offers a neo-classical explanation of the Meese-Rogoff puzzle and mimics the failure of fundamentals to explain nominal exchange rates in a linear setting. Finally, the model naturally generates the negative slope in the standard forward market regression. </p>
A Case Study of the Ergonomic Consequences of Engineering Decisions
Authors: Neumann Patrick , Kihlberg S. , Medbo P. , Winkel Jorgen 
Published: September 2022

<p>This paper presents a case study of the ergonomic consequences of engineering change. Within the context of a project to re-design an electronics assembly system a decision was made to automate transportation functions. A manual batch-cart system was changed to a line-system with automatic conveyors. </p>
Organisational Design and the (dis)Integration of Human Factors in Production System Development
Authors: Neumann Patrick , Winkel Jorgen 
Published: September 2022

<p>This paper describes and generalises experiences from two cases of production system development in the Swedish context. We have observed the successful application of ergonomics to be related to the lack of coordination of human factorsacross groups responsible for different stages of the production system designprocess. This problem is magnified by the tendency for ‘ergonomics’ to be the responsibility of Human Resources departments who are distanced from they design process, rather than engineering teams directly engaged in design. Available toolsto improve the integration of ergonomics considerations into the design process are briefly presented and discussed. </p>