bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Kepemilikan Institusional, Kebijakan Deviden, Pertumbuhan Perusahaan dan Ukuran Perusahaan Terhadap Kebijakan Hutang yang Dimoderasi oleh Rasio Keuangan
Authors: Mufidah Mia Nur , Fachrurrozie Fachrurrozie 
Published: August 2022

ABSTRACTThe purpose of this study is to analyze the effect of institutional ownership, dividend policy, firm growth and firm size on debt policy with financial ratios as a moderating variable. The population of this study was 186 manufacturing companies listed on the Indonesia Stock Exchange (IDX) for the period 2015 – 2019. Based on the purposive sampling method, the research sample was obtained as many as 26 companies with 117 data units. The analysis of this study uses descriptive statistics, multiple linear regression and Moderated Regression Analysis (MRA) with the help of SPSS 25. The results of this study indicate that institutional ownership, firm growth and firm size have a positive and significant effect on debt policy, while dividend policy has a negative and significant effect. On debt policy, and financial ratios can only moderate the effect of firm size on debt policy, while for institutional ownership, dividend policy and firm growth cannot be moderated. The conclusion of this study is that the higher the dividend policy, the lower the company's debt policy, so that the company's capital can be taken from retained earnings. Keywords: Debt Policy; Institutional Ownership; Dividend Policy; Company Growth; Firm Size ABSTRAKTujuan penelitian ini untuk menganalisis pengaruh kepemilikan institusional, kebijakan dividen, pertumbuhan perusahaan dan ukuran perusahaan terhadap kebijakan hutang dengan rasio keuangan sebagai variabel moderating. Populasi penelitian ini sebanyak 186 perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia (BEI) periode 2015 – 2019. Berdasarkan metode purposive sampling, Sampel penelitian diperoleh sebanyak 26 perusahaan dengan 117 unit data. Analisis penelitian ini menggunakan statistik deskriptif, regresi linier berganda dan Moderated Regression Analysis (MRA) dengan bantuan SPSS 25. Hasil penelitian ini menunjukkan bahwa kepemilikan institusional, pertumbuhan perusahaan dan ukuran perusahaan berpengaruh positif dan signifikan terhadap kebijakan hutang, sedangkan kebijakan deviden berpengaruh negatif dan signifikan terhadap kebijakan hutang, serta rasio keuangan hanya dapat memoderasi pengaruh ukuran perusahaan terhadap kebijakan hutang, sedangkan untuk kepemilikan institusional, kebijakan dividen dan pertumbuhan perusahaan tidak dapat di moderasi. Kesimpulan dari penelitian ini adalah semakin tinggi kebijakan dividen semakin rendah kebijakan hutang perusahaan, sehingga modal perusahaan dapat diambil dari laba ditahan.Kata Kunci: Kebijakan Hutang; Kepemilikan Institusional; Kebijakan Dividen; Pertumbuhan Perusahaan; Ukuran Perusahaan
PENGARUH PROFITABILITAS DAN LEVERAGE TERHADAP SUSTAINABILITY REPORT DENGAN NILAI PERUSAHAAN SEBAGAI VARIABEL INTERVENING (Studi Empiris pada Perusahaan Pertambangan yang Terdaftar di Bursa Efek Indonesia tahun 2014-2018)
Authors: Nurdiah Nurdiah , Asrori Asrori 
Published: August 2022

ABSTRACT This study is to determine the effect of 1) Profitability on Sustainability Report, 2) Leverage on Sustainability Report, 3) Company Value on Sustainability Report, 4) Profitability on Firm Value, 5) Leverage on Firm Value, 6) Profitability on Sustainability Report through company value, 7) Leverage on Sustainability Report through company value. The sampling technique was using purposive sampling method. Data collection techniques using documentation. Data analysis techniques include 1) Descriptive statistics 2) Classical Assumption Test: Normality, Multicollinearity, Autocorrelation and Heteroscedasticity. 4) Hypothesis testing of path analysis methods and Sobel Test. The results showed that: 1) Return on assets has a positive and significant effect on company value in mining companies listed on the IDX in 2014-2018. 2) Earning Per Share has a positive and significant effect on Sustainability Report through company value at mining companies listed on the IDX in 2014-2018. 3) 10. Leverage has a positive and significant effect on the Sustainability Report through the company value of mining companies listed on the IDX in 2014-2018. Keywords: Return on Asset, Earning Per Share, Debt to Equity Ratio, Price to Book Value, Sustainability Reporting. ABSTRAKPenelitian ini untuk mengetahui pengaruh 1) Profitabilitas terhadap Sustainability Report, 2) Leverage terhadap Sustainability Report, 3) Nilai Perusahaan terhadap Sustainability Report, 4) Profitabilitas tehadap Nilai Perusahaan, 5) Leverage terhadap Nilai Perusahaan, 6) profitabilitas terhadap Sustainability Report melalui nilai perusahaan, 7) Leverage terhadap Sustainability Report melalui nilai perusahaan. Teknik pengambilan sampel menggunakan metode purposive sampling. Teknik pengumpulan data menggunakan dokumentasi. Teknik analisis data meliputi 1) Statistik deskriptif 2) Uji Asumsi Klasik: Normalitas, Multikolinearitas, Autokorelasi dan Heteroskedastisitas. 4) Pengujian Hipotesis metode analisis jalur dan Sobel Test. Hasil penelitian menunjukkan bahwa : 1) Return On Asset mempunyai pengaruh positif dan signifikan terhadap nilai perusahaan pada perusahaan pertambangan yang terdaftar di BEI tahun 2014-2018. 2) Earning Per Share berpengaruh secara positif dan signifikan terhadap Sustainability Report melalui nilai perusahaan pada perusahaan pertambangan yang terdaftar di BEI tahun 2014-2018. 3) 10. Leverage berpengaruh secara positif dan signifikan terhadap Sustainability Report melalui nilai perusahaan pada perusahaan pertambangan yang terdaftar di BEI tahun 2014-2018.Kata Kunci: Return On Asset, Earning Per Share, Debt to Equity Ratio, Price to Book Value, Sustainability Repor
PTEN Immunohistochemistry
Authors: Terra Simone Antunes , de Arruda Lourenção, Pedro Luiz Toledo , Rodrigues Maria Aparecida Marchesan 
Published: August 2022

Context.—
Intestinal neuronal dysplasia type B (IND B) is a complex entity involving the enteric nervous system, clinically manifested with constipation in infancy. Diagnosis has been established by histopathologic analysis of rectal biopsies. However, the criteria for the diagnosis have been questioned and modified, hindering diagnostic practice.

Objective.—
To analyze the applicability of PTEN immunohistochemistry in the diagnosis of IND B and to compare with control cases and cases of Hirschsprung disease (HD).

Design.—
PTEN immunohistochemical expression was analyzed in colorectal samples from 29 cases of IND B and compared with 4 control cases and 6 cases of HD. The pattern of PTEN immunoexpression was analyzed in glial cells of the submucosal and myenteric nerve plexuses and in neural fibrils of the muscularis propria using a scoring system.

Results.—
Marked reduction or absence of PTEN expression was observed in glial cells of the submucosal nerve plexuses in all cases of the IND B group and in the myenteric nerve plexuses in 28 of 29 cases (96.5%). Lack of PTEN expression was detected in neural fibrils within the muscularis propria in 21 of 29 cases (72%) of the IND B group. PTEN expression was positive in the same neural structures of the control and HD groups.

Conclusions.—
PTEN immunohistochemistry may be a valuable tool in the diagnostic evaluation of IND B. Lack of or reduction of PTEN expression in neural fibrils within the muscularis propria suggests that involvement of the neuromuscular junction may be a key event in the pathogenesis of the motility disturbance occurring in IND B.
Variability, Correlation and Path Analysis for Grain Yield Characters of Rice (Oryza sativa L.) Genotypes
Authors: Mathew Akhila , Lavanya G. Roopa , Kumar R. 
Published: August 2022

The present investigation with thirty-four accessions of rice (Oryza sativa L.) genotypes (26 Advanced breeding lines (ABL’s),7 Dhan varieties and one check) were investigated to study variability, correlation and path analysis for yield contributing characters carried out at the Field Experimentation Centre, Department of Genetics and Plant Breeding, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj during Kharif-2021 in Randomized Block Design with three replications. NDR 359 rice variety was used as the check. The data was recorded for 13 quantitative traits viz Days to 50% flowering, Plant height (cm), Flag leaf length (cm), Flag leaf width (cm), Number of total tillers per hill, Number of panicles per hill, Panicle length (cm), Number of spikelets per panicle, Days to maturity, Biological index, Harvest index (%), Test weight (g), Grain yield per hill (g) using agro-morphological traits. The mean sum of squares due to genotypes was highly significant for all the quantitative characters in ANOVA. The characters with high range estimates of GCV and PCV (Grain yield per hill), heritability (days to maturity) and genetic advance as percent mean (number of spikelets per panicle,) should be given top priority during selection. For character association, grain yield per hill showed positive significance with flag leaf length, number of spikelets per panicle, biological yield, harvest index, number of tillers per hill, biological yield because it help in determining the nature and extent of the relationship existing between the yield and its contributing components and their association.Path analysis further proved about the direct and indirect effect of characters on grain yield. Days to 50% flowering, flag leaf width, number of panicles per hill, biological yield, harvest index showed positive direct effect at both genotypic and phenotypic level indicating their importance in breeding programme. So direct selection of the above characters will be rewarding.
Evaluation of the Hepatic effects of Caladium hortulanum Leaf Extract on Wistar Albino Rats
Authors: Oforibika G. A. , Obia C. 
Published: August 2022

This study evaluates the hepatic effects of caladium hortulanum leaf extract on wistar albino rats. A total of twenty-four (24) rats were randomly divided into 4 groups labeled A, B, C and D and kept in a well-ventilated room. Group A served as control and these rats were fed distilled water. Rats in the groups B, C, and D were given three (3) different doses of the leaf extract (1.5, 3.5 and 5.0mL/Kgbw) respectively. They were administered once daily for 14 and 28 days consecutively. Animals were sacrificed 24 hours after the last treatment. Blood samples were collected into heparinized sample bottles for analysis. All liver enzymes and histology results were normal for short term use in this study. Alkaline phosphatase was increased in a dose dependent manner when used in the long term. Histopathological changes were seen in all doses when Caladium hortulanum leaf extract was used in the long term. This suggests that this medicinal plant cause some degree of hepatic damage when used for continuously for long periods at a time. Care should therefore be taken with their use, prescriptions reviewed as needed and regular monitoring of liver function should be instituted.
Designing Geometric Degrees of Freedom in ReO3‐Type Coordination Polymers
Authors: Burger Stefan , Hemmer Karina , Mayer David C. , Vervoorts Pia , Daisenberger Dominik , Zaręba Jan K. , Kieslich Gregor 
Published: August 2022

AbstractEngineering the interplay of structural degrees of freedom that couple to external stimuli such as temperature and pressure is a powerful approach for material design. New structural degrees of freedom expand the potential of the concept, and coordination polymers as a chemically versatile material platform offer fascinating possibilities to address this challenge. Here, we report a new class of perovskite‐like AB2X6 coordination polymers based on a [BX3] − ReO3‐type host network ([Mn(C2N3)3] −), in which the spatial orientation of divalent A2+ cations ([R3N(CH2)nNR3]2+) with separated charge centers that bridge adjacent ReO3‐cavities is introduced as a new geometric degree of freedom. Herringbone and head‐to‐tail order pattern of [R3N(CH2)nNR3]2+ cations are obtained by varying the separator length n and, together with distortions of the pseudocubic [BX3] − network, they determine the materials’ stimuli‐responsive behavior such as counterintuitive large negative compressibility and uniaxial negative thermal expansion. This new family of coordination polymers highlights the chemists’ capabilities of designing matter on a molecular level to address macroscopic material functionality and underpins the opportunities of the design of structural degrees of freedom as a conceptual framework for rational material synthesis in the future.
High Photocurrent Anisotropy in Domain‐Engineered Ferroelectrics for Visible‐Light Polarization Detection
Authors: Matsuo Hiroki , Noguchi Yuji 
Published: August 2022

AbstractVisible‐light polarization detection is a critical challenge for next‐generation light communication and imaging technologies. While low‐dimensional nanomaterials exhibit polarization‐dependent photocurrents originating from their anisotropic absorption, ferroelectric photovoltaics provide a photocurrent derived from spatial inversion symmetry breaking. Here, it is reported that domain‐engineered ferroelectrics are promising materials for visible‐light polarization detection. Polarization angle‐resolved photocurrent measurements demonstrate that the introduction of domain walls in ferroelectric BiFe0.95Mn0.05O3 films increases the photocurrent anisotropy ratio up to 7.9 under visible light with hν = 2.4 eV (λ = 515 nm), which is much higher than that of typical nanomaterials (≈2–3). Simulations of polarization‐dependent photocurrents show that the domain walls provide an additional degree of freedom for designing ferroelectrics with quite high photocurrent anisotropy. This study opens up the possibility of developing ferrophotovoltaic‐based visible‐light polarization detectors with simple device structures.
Radical C−H Alkylation with Ethers and Unactivated Cycloalkanes toward the Assembly of Tetrasubstituted Amino Acid Derivatives
Authors: San Segundo Marcos , Correa Arkaitz 
Published: August 2022

AbstractA radical α−C−H alkylation of a collection of N‐picolinamide amino acid derivatives with ethers and cycloalkanes as chemical feedstock is described. This cross‐dehydrogenative coupling is distinguished by its reliable scalability and removable auxiliary group, and enables the assembly of a variety of tri‐ and tetrasubstituted amino acid compounds.magnified image
Constrained robust Bayesian optimization of expensive noisy black‐box functions with guaranteed regret bounds
Authors: Kudva Akshay , Sorourifar Farshud , Paulson Joel A. 
Published: August 2022

AbstractMany real‐world design problems involve optimization of expensive black‐box functions. Bayesian optimization (BO) is a promising approach for solving such challenging problems using probabilistic surrogate models to systematically tradeoff between exploitation and exploration of the design space. Although BO is often applied to unconstrained problems, it has recently been extended to the constrained setting. Current constrained BO methods, however, cannot identify solutions that are robust to unavoidable uncertainties. In this article, we propose a robust constrained BO method, constrained adversarially robust Bayesian optimization (CARBO), that addresses this challenge by jointly modeling the effect of the design variables and uncertainties on the unknown functions. Using exact penalty functions, we establish a bound on the number of CARBO iterations required to find a near‐global robust solution and provide a rigorous proof of convergence. The advantages of CARBO are demonstrated on two case studies including a non‐convex benchmark problem and a realistic bubble column reactor design problem.
Expanding the phenotypic spectrum of COLEC10‐Related 3MC syndrome: A glimpse into COLEC10‐Related 3MC syndrome in the Ashkenazi Jewish population
Authors: Rabin Rachel , Hirsch Yoel , Chung Wendy K. , Ekstein Josef , Levy‐Lahad Ephrat , Zuckerman Shachar , Mor‐Shaked Hagar , Meiner Vardiella , Booth Kevin T. , Pappas John 
Published: August 2022

AbstractBi‐allelic variants in COLEC11 and MASP1 have been associated with 3MC syndrome, a clinical entity made of up four rare autosomal recessive disorders: Carnevale, Mingarelli, Malpuech, and Michels syndromes, characterized by variable expression of facial dysmorphia, cleft lip/palate, postnatal growth deficiency, hearing loss, cognitive impairment, craniosynostosis, radioulnar synostosis, and genital and vesicorenal anomalies. More recently, bi‐allelic variants in COLEC10 have been described to be associated with 3MC syndrome. Syndromic features seen in 3MC syndrome are thought to be due to disruption of the chemoattractant properties that influence neural crest cell migration. We identified nine individuals from five families of Ashkenazi Jewish descent with homozygosity of the c.311G > T (p.Gly104Val) variant in COLEC10 and phenotype consistent with 3MC syndrome. Carrier frequency was calculated among 52,278 individuals of Jewish descent. Testing revealed 400 carriers out of 39,750 individuals of Ashkenazi Jewish descent, giving a carrier frequency of 1 in 99 or 1.01%. Molecular protein modeling suggested that the p.Gly104Val substitution alters local conformation. The c.311G > T (p.Gly104Val) variant likely represents a founder variant, and homozygosity is associated with features of 3MC syndrome. 3MC syndrome should be in the differential diagnosis for individuals with short stature, radioulnar synostosis, cleft lip and cleft palate.
Towards osteogenic bioengineering of human dental pulp stem cells induced by incorporating Prunus amygdalus dulcis extract in polycaprolactone‐gelatin nanofibrous scaffold
Authors: Valizadeh Nasrin , Salehi Roya , Roshangar Leila , Agbolaghi Samira , Mahkam Mehrdad 
Published: August 2022

AbstractIn this study, the osteo‐inductive potential of Prunus amygdalus dulcis (SA) extract that loaded with different concentrations in poly‐ε‐Caprolactone/gelatin (PCL/GEL) nanofibrous scaffolds was investigated. The morphology and composition of nanofibers were evaluated using field emission scanning electron microscope and FT‐IR spectroscopy. Mechanical properties, hydrophilicity and pore structures were determined by tensile test, contact angle, and N2 adsorption–desorption isotherm, respectively. By incorporation of SA extract into PCL/GEL nanofibers, mechanical capabilities as well as their physical qualities were improved. The response of human dental pulp stem cells on prepared scaffolds were studied using MTT assay, alkaline phosphatase activity, alizarin red assay, and quantitave real‐time PCR analysis. The SA loaded nanofibers presented excellent cell attachment and enhanced osteoblast proliferation and mineralization compared to the pristine PCL/GEL nanofibers. The analysis revealed the addition SA extract to PCL/GEL nanofibers increased the expression of osteogenic genes significantly. According to our findings, PCL/GEL/SA nanofibers show a lot of potential for bone tissue engineering.
Wage arbitrage through skilled emigration: Evidence from the Pacific Islands
Authors: Chand Satish , Clemens Michael , Dempster Helen 
Published: August 2022

AbstractSkilled workers in poor countries earn wages a fraction of that of their counterparts in rich nations. Here, we estimate the opportunities for wage arbitrage from emigration of workers from the Pacific Islands into Australia and New Zealand. Our calculations, based on wages earned by graduate accountants, computer science graduates and cooks with Certificate III qualifications, reveal wage premiums of a factor of up to 10 from emigration. Likewise, the cost of training to Australian standards within the Pacific Islands is as little as a third of that in Australia meaning that the total factor of economic arbitrage is 30.
Behavioral beliefs about genetic counseling among high‐risk Latina breast cancer survivors in Florida and Puerto Rico
Authors: Rivera Rivera Jessica N. , Conley Claire C. , Castro‐Figueroa Eida M. , Moreno Laura , Dutil Julie , García Jennifer D. , Ricker Charité , Quinn Gwendolyn P. , Soliman Hatem , Vadaparampil Susan T. 
Published: August 2022

AbstractCompared with non‐Hispanic White women, Latina women are less likely to receive genetic counseling (GC) and testing (GT) following BC diagnosis. This study used secondary data analysis to explore beliefs about GC among Latina BC survivors in and outside the US mainland. GC/GT‐naïve, high‐risk, Spanish‐preferring Latina BC survivors (n = 52) in FL and PR completed the Behavioral Beliefs about GC scale. Participants reported high positive beliefs about GC (M = 4.19, SD = 0.92); the majority agreed that GC was beneficial to understand cancer risk (90%) and promote discussion (87%) in their family. Participants reported low‐to‐moderate scores for barriers (Ms = 1.53–3.40; SDs = 0.59–0.90). The most frequently endorsed barriers were desire for additional GC information (M = 3.44; SD = 0.90), and GC logistic concerns (M = 2.71; SD = 0.80). No statistically significant differences for barriers and benefits scales were identified by place of residence (all ps ≥ 0.12). These findings highlight the importance of delivering culturally sensitive GC information to high‐risk Latina BC survivors.
Bias behind closed doors: Chinese consumers' perception of foreign wines
Authors: Christian Jesse Elias , Wang Di 
Published: August 2022

AbstractAlthough considerable research has explored consumer ethnocentrism and conspicuous consumption effects independently, a meaningful quantitative analysis of the interaction of such effects on consumer perception is yet to be undertaken. This study aims to provide insight into these effects by examining the impacts of consumer ethnocentrism and consumption setting on foreign Country‐of‐Origin (COO) effects in a Chinese consumer wine market context. A total of 324 wine consumers in mainland China participated in a 3 (COO: France vs. Australia vs. China) × 2 (Consumption Setting: Public vs. Private) × continuous (Chinese consumer ethnocentrism) between‐subject, factorial design experiment. The study finds that Chinese consumers favor French red wine when compared with its Australian and Chinese counterparts but shows that Australian wines still benefit through smaller, indirect COO effects. Additionally, French COO effects are mediated by the utilitarian and hedonic meanings of red wine and moderated by consumer trait ethnocentrism and the consumption setting. This paper contributes to the understanding of culturally informed self‐regulation of consumer behaviors and how Chinese consumer ethnocentrism interacts with consumption settings to alter a consumer's perception of foreign goods. The findings of this paper also provide practical insight into Chinese wine consumers' perceptions and decision‐making processes for wine exporters.
Central positional vertigo as first initial multiple sclerosis symptom: A case report with systematic review
Authors: Meshref Mostafa , Shaheen Ahmed , Elmatboly Abdelmagid M. , Hamdallah Aboalmagd , Abdella Walid Shaban , Amro Yara , Khairat Shiamaa M. , Swed Sarya 
Published: August 2022

AbstractMultiple sclerosis is a disease that affects the central nervous system, resulting in various symptoms such as vision, physical activity, and stability. Central positional vertigo as initial multiple sclerosis symptoms are a rare case. It increases the attention of doctors to follow accurate measurements to diagnose multi sclerosis regarding the initial symptoms.
Giant internal carotid artery aneurysms and porcelain aorta in an elderly patient with Marfan syndrome
Authors: Yagi Hiroki , Takeda Norifumi , Hosoya Yumiko , Yamauchi Haruo , Komuro Issei 
Published: August 2022

AbstractMarfan syndrome (MFS) an inherited disorder caused by FBN1 gene variants, is well known to cause lethal aortic aneurysm and dissections at a relatively young age. Here, we report giant internal carotid artery aneurysms (ICAAs) and porcelain aorta in an elderly patient with MFS.