bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Dynamic Scheduling Algorithm Based on Endogenous Security
Authors: Miao Weiwei , Zeng Zeng , Zhang Rui , Xi Zesheng 
Published: November 2022

Abstract
Endogenous security enables the network to have its own immunity against various known and unknown attacks. The redundant executive scheduling strategy is an important link, which determines the security and reliability of the architecture. The existing scheduling strategy lacks consideration of scheduling time and the number of executors, and does not flexibly utilize attack feedback information. They are relatively simple and lack of security to a certain extent. Based on this, this paper proposes a dynamic scheduling algorithm by introducing the consideration of scheduling attributes and historical attack information. Firstly, a scheduling trigger based on the joint control of working time and abnormal feedback is designed. Then, the dynamic calculation formulas under different attack scenarios are constructed by using historical attack feedback information. Finally, a complete scheduling scheme is proposed. Experiments show that the dynamic performance of the algorithm is better than the fixed strategy. In addition, the algorithm improves the utilization of the actuator and achieves a good balance between reliability and efficiency.
Research on conformance test sequence generation of the communication unit adaptation specification protocol
Authors: Zhu Zixu , Ju Hanji , Li Dan , Qie Shuang , Du Yina , Wu Zhongxing 
Published: November 2022

Abstract
The communication unit adaptation specification protocol of the customer-side energy measuring equipment and its conformance test is important for realizing massive equipment access to the energy internet flexibly and efficiently. The conformance test of communication protocol is the key to generating complete and efficient test sequences. In allusion to the problem of conformance test sequence generation of communication unit adaptation specification protocol, the paper first formally describes the protocol based on a finite state machine, and then further carries out the research on conformance test sequence generation based on T method, U method and U+ method. The results show that the test sequence generated by U+ method has the ability of state verification and the length is 22.1% shorter than that of U method. Its redundancy is slightly less than that of T method and the error detection ability is much better. Therefore, U+ method is more suitable for the conformance test sequence generation of communication unit adaptation specification protocol.
Nitrogen solubility test under different pressures and temperatures for nitrogen-sealed transformers
Authors: Li Jiansheng , Yang Xiaoping , Wang Shengquan 
Published: November 2022

Abstract
The 35kV nitrogen sealed transformers are widely used due to its excellent explosion-proof performance. But for higher voltage transformers, the nitrogen solubility under different temperatures and pressures is unknown, which restricts the design of nitrogen layer volume. In this paper, a nitrogen solubility test platform is built. And the nitrogen solubility in insulating oil under different oil temperatures and nitrogen pressures is obtained. Besides, the relationship between pressure, temperature and nitrogen solubility is established, which provides an important basis for transformer design.
Rare desynchronization events in power grids: on data implementation and dimensional reductions
Authors: Ritmeester Tim , Meyer-Ortmanns Hildegard 
Published: November 2022

Abstract
We discuss the frequency of desynchronization events in power grids for realistic data input. We focus on the role of time correlations in the fluctuating power production and propose a new method for implementing colored noise that reproduces non-Gaussian data by means of cumulants of data increment distributions. Our desynchronization events are caused by overloads. We extend known and propose different methods of dimensional reduction to considerably reduce the high-dimensional phase space and to predict the rare desynchronization events with reasonable computational costs. The first method splits the system into two areas, connected by heavily loaded lines, and treats each area as a single node. The second method considers a separation of the timescales of power fluctuations and phase angle dynamics and completely disregards the latter. The fact that this separation turns out to be justified, albeit only to exponential accuracy in the strength of fluctuations, means that the number of rare events does not sensitively depend on inertia or damping for realistic heterogeneous parameters and long correlation times. Neither does the number of desynchronization events automatically increase with non-Gaussian fluctuations in the power production as one might have expected. On the other hand, the analytical expressions for the average time to desynchronization depend sensitively on the finite correlation time of the fluctuating power input.
Active particles using reinforcement learning to navigate in complex motility landscapes
Authors: Monderkamp Paul A , Schwarzendahl Fabian Jan , Klatt Michael A , Löwen Hartmut 
Published: November 2022

Abstract
As the length scales of the smallest technology continue to advance beyond the micron scale it becomes increasingly important to equip robotic components with the means for intelligent and autonomous decision making with limited information. With the help of a tabular Q-learning algorithm, we design a model for training a microswimmer, to navigate quickly through an environment given by various different scalar motility fields, while receiving a limited amount of local information. We compare the performances of the microswimmer, defined via time of first passage to a target, with performances of suitable reference cases. We show that the strategy obtained with our reinforcement learning model indeed represents an efficient navigation strategy, that outperforms the reference cases. By confronting the swimmer with a variety of unfamiliar environments after the finalised training, we show that the obtained strategy generalises to different classes of random fields.
Outcomes of bariatric surgery in patients with inflammatory bowel disease from a French nationwide database
Authors: Corbière Lisa , Scanff Alexandre , Desfourneaux Véronique , Merdrignac Aude , Ingels Anne , Thibault Ronan , Bouguen Guillaume , Bergeat Damien 
Published: November 2022

Abstract

Background
The outcomes of bariatric surgery (BS) in patients with chronic inflammatory bowel disease (IBD) remain rarely described. We aimed to evaluate the 90-day morbidity and mortality rates, and the risk of IBD complications 2 years after BS.

Method
Patients from the French Programme de Médicalisation des Systèmes d’Information (PMSI) database who underwent a primary BS between 2016 and 2018 were included. We identified patients with a previous diagnosis of IBD. Postoperative 90-day (POD90) morbidity and mortality rates were compared between the two groups. The evolution of IBD was followed 2 years after BS.

Results
Between 2016 and 2018, 138 980 patients underwent primary BS, including 587 patients with IBD: 326 (55.5 per cent) with Crohn’s disease (CD) and 261 (44.5 per cent) with ulcerative colitis (UC). The preferred surgical technique was sleeve gastrectomy, especially in the IBD group (81.1 per cent), followed by gastric bypass (14.6 per cent). Patients with IBD had more comorbidities (Charlson Comorbidity Index of 1 or more, hypertension, and diabetes; P &lt; 0.001) than those without IBD. The POD90 mortality rate did not differ between the two groups (0.049 per cent in the IBD group versus 0 per cent in the non-IBD group), but more unscheduled rehospitalizations at POD90 were observed in patients with IBD (6.0 per cent versus 3.7 per cent; P = 0.004). Two years after BS, 86 patients (14.6 per cent) in the IBD group had at least one unplanned readmission for the management of their IBD; 15 patients stayed for 3 or more days. After multivariable analysis, patients with CD had an independent elevated risk of IBD-related unplanned readmissions 2 years after BS versus UC (adjusted odds ratio 1.90, 95 per cent c.i. 1.22 to 2.97; P = 0.005).

Conclusion
In a highly selected cohort of patients with well-controlled IBD, BS did not result in added mortality or morbidity. A point of vigilance must be underlined regarding BS in patients with CD.
IBC-Ox26 Concomitant hiatal hernia repair during bariatric surgery: is it the reinforcement making the difference?
Authors: Boru C , Iossa A , Silecchia G 
Published: November 2022

Abstract

Background
Concomitant hiatal hernia repair (HHR) in patients who undergo bariatric surgery (BS) is under debate.

Aims
To evaluate on long-term the safety and efficacy of posterior cruroplasty (PC), simple or reinforced with a biosynthetic, absorbable mesh, performed during BS. Primary endpoint: PC's failure, defined as symptomatic HH recurrence, nonresponding to conservative treatment and requiring revisional surgery.

Methods
The prospective database of 1948 patients undergoing BS in a center of excellence between 2011-2020 was searched. Intraoperative measurement of the hiatal surface area (HSA) was performed routinely.

Results
268 patients undergone BS and concomitant HHR (13.7%). Simple PC (group A, 165 patients) was performed during 137 sleeve gastrectomies LSG, 5 re- sleeves and 23 gastric bypasses LGB; mean BMI 43.4 ± 5.8 kg/m2, HSA mean size 3.4 ± 2 cm2. Reinforced PC (group B) was performed in 102 cases: 64 primary LSG, 23 LGB and 15 revisions of LSG; mean BMI 44.6 ± 7.7 kg/m2, HSA mean size 6.7 ± 2 cm2. PC's failure, with intrathoracic migration (ITM) was encountered in 12 cases (7.5%) of simple vs. only 4 cases (3.9%) of reinforced PC (p=0.23); hence, a repeat, reinforced PC and LGB was performed in all cases. No mesh-related complications were registered perioperatively or after long-term follow-up (mean 61 months), minimum 12 months. Only one case of cardiac metaplasia was detected 4 years postoperatively; conversion to LGB, with reinforced redo of the PC was performed. The Cox hazard analysis showed that the use of more than four stitches for cruroplasty represents a negative factor on recurrence (HR = 8; p &lt; 0.05).

Conclusions
Our results support the use of bioabsorbable, synthetic mesh as reinforcement of HH &gt; 4 cm2 in obese patients during BS, showing excellent recurrence rate results (4%). Accurate patients’ and technique's selection, combined with PC (simple or reinforced) ensure effectiveness and safety, with a combined rate of failure (HH recurrence) at 4 years of 6.0%.
IBCOx-9 Enhanced Recovery After Metabolic Surgery: Results of a De Novo Program for Same-day Cases in a Free-standing Ambulatory Surgical Center
Authors: Billing P , Billing J , Balee S 
Published: November 2022

Abstract

Background
Metabolic Surgery (MS) is commonly performed in a hospital setting. Same-day case (SDC) MS has not been performed due to concern for patient safety and complications after discharge. Procedures performed in ambulatory surgical centers (ASC) provide several advantages over hospital-based surgery by improving patient experience, decreasing hospital acquired infections, decreasing cost, and increasing access to MS. We previously reported our experience with performing 2,534 patients who underwent sleeve gastrectomy (SG) in an ASC. The ability to replicate this program validates the safety of Enhanced Recovery After Metabolic Surgery (ERAMS) protocols. We have replicated the SDC program with a new team in a new facility using previously established ERAMS protocols.

Objective
To report safe and effective protocols for same-day metabolic surgery.

Setting
Free-standing ASC,

Methods
Data was collected retrospectively for all patients undergoing MS from June 2019 - December 2019, n = 18. Revisional procedures were not excluded from this study. Patients were excluded from the ASC criteria if they weighed &gt;400 pounds, if anticipated surgery time was &gt; 2 hours, if the patient had impaired mobility limiting early ambulation, if they had chronic obstructive pulmonary disease, severe sleep apnea or moderate cardiac risk. All surgeries were performed laparoscopically using a 38 French Bougie, staple line was initiated 4 cm from the pylorus. No buttress material was used. The upper 3 cm of the staple line was oversewn. Intraoperative blood pressure was raised 20 mm Hg to identify bleeding along the staple line. Drains were not routinely used. Patients were given 3-4 liters of intravenous fluid prior to discharge. Patients were discharged once ASC discharge criteria was met: ambulating, voiding, tolerating fluids, pain and nausea controlled and normal vital signs.

Results
Mean age was 41.3 years (21-70). Mean preoperative body mass index (BMI) was 43.2 (32-55). Mean operative time was 88.1 minutes (54-146). Average length of stay at the ASC was 386.7 minutes (165-547). There were no re-admissions, re-operations, or direct transfers from the ASC to the hospital. One patient was seen in the emergency department (ED) within 30 days (postoperative day 3) for anxiety and dysphagia. She was discharged from the ED after negative studies. Seventeen patients had SG. Four had concomitant hiatal hernia pairs. One had concomitant liver biopsy. Two patients were revisional: one patient had a previous gastric band; one patient had previous banded sleeve gastrectomy.

Conclusion
With an experienced metabolic surgeon, appropriate protocols, and a consistent operative team, MS can be performed safely as a SDC in a free-standing ASC on selective patients.
IBC-Ox24 Routine Oversewing of Staple Lines to Prevent Leaks is Unnecessary in Patients with Normal Iintraoperative Indocyanine Green (ICG) Perfusion Studies Undergoing Sleeve Gastrectomy
Authors: Billy H , Simpson T 
Published: November 2022

Abstract

Anastomotic staple line leaks following laparoscopic sleeve gastrectomy is a devastating complication. Gastric ischemia and poor tissue perfusion has been hypothesized to be a contributing factor. Various interventions including oversewing of staple lines are commonly used hoping to decrease staple line leaks. Indocyanine green (ICG) can be used to assess bowel perfusion and anastomotic viability following laparoscopic surgery. 50 consecutive patients underwent laparoscopic sleeve gastrectomy utilizing intravenous administration of ICG to assess tissue perfusion and the need for staple line oversewing.

Methods
50 consecutive patients undergoing laparoscopic sleeve gastrectomy were studied intraoperatively after completion of sleeve gastrectomy using intravenous administration of ICG. 7.5 mg of ICG was administered intravenously. Arterial perfusion and end stage tissue perfusion of the completed sleeve gastrectomy was then evaluated. Vascular arterial inflow of the gastric cardia, body and antrum was carefully evaluated both anteriorly and posteriorly for evidence of delayed tissue perfusion or tissue ischemia.

Results
In all cases the staple line was examined for staple line formation and evidence of poor tissue perfusion using ICG. Both anterior and posterior evaluation was performed of the distal esophagus, gastric cardia, gastric body and antrum. Absence of tissue perfusion in the resected gastric body was used as a comparison control in all cases. ICG perfusion of the gastric cardia, body and antrum was found to be excellent and brisk in all patients. There were no areas of decreased perfusion or tissue ischemia. Oversewing of the staple line was avoided in all cases. Hemostatic clips were deployed as needed for staple line bleeding until there was no evidence of bleeding on visual inspection and final ICG administration. Patients were followed for evidence of leakage or obstruction for 30 days following completion of the sleeve gastrectomy. There were no leaks, there were no deaths. There were no obstructions and no readmissions. There were no complications related to administration of ICG. Average operative time was 48.7 minutes.

Conclusions
Our series of 50 consecutive sleeve gastrectomies utilizing ICG to assess for tissue perfusion demonstrated no evidence of tissue perfusion deficiencies along the staple line or at the angle of His. Staple line oversewing was not used in any patients. Staple line oversewing in cases without evidence of tissue perfusion deficits on ICG evaluation following sleeve gastrectomy is unnecessary. Further multicenter studies and prospective randomized series are necessary to confirm these initial findings.
Targeting aberrant dendritic integration to treat cognitive comorbidities of epilepsy
Authors: Masala Nicola , Pofahl Martin , Haubrich André N , Sameen Islam Khondker Ushna , Nikbakht Negar , Pasdarnavab Maryam , Bohmbach Kirsten , Araki Kunihiko , Kamali Fateme , Henneberger Christian , Golcuk Kurtulus , Ewell Laura A , Blaess Sandra , Kelly Tony , Beck Heinz 
Published: November 2022

Abstract
Memory deficits are a debilitating symptom of epilepsy, but little is known about mechanisms underlying cognitive deficits. Here, we describe a Na+ channel-dependent mechanism underlying altered hippocampal dendritic integration, degraded place coding and deficits in spatial memory.
Two-photon glutamate uncaging experiments revealed a marked increase in the fraction of hippocampal first-order CA1 pyramidal cell dendrites capable of generating dendritic spikes in the kainate model of chronic epilepsy. Moreover, in epileptic mice dendritic spikes were generated with lower input synchrony, and with a lower threshold. The Nav1.3/1.1 selective Na+ channel blocker ICA-121431 reversed dendritic hyperexcitability in epileptic mice, while the Nav1.2/1.6 preferring anticonvulsant S-Lic did not. We used in vivo two-photon imaging to determine if aberrant dendritic excitability is associated with altered place-related firing of CA1 neurons. We show that ICA-121431 improves degraded hippocampal spatial representations in epileptic mice. Finally, behavioural experiments show that reversing aberrant dendritic excitability with ICA-121431 reverses hippocampal memory deficits.
Thus, a dendritic channelopathy may underlie cognitive deficits in epilepsy and targeting it pharmacologically may constitute a new avenue to enhance cognition.
Household- Versus Incentive-Based Contact Investigation for Tuberculosis in Rural South Africa: A Cluster-Randomized Trial
Authors: Hanrahan Colleen F , Nonyane Bareng Aletta Sanny , Lebina Limakatso , Mmolawa Lesego , Siwelana Tsundzukani , West Nora S , Albaugh Nicholas , Martinson Neil , Dowdy David W 
Published: November 2022

Abstract

Background
Household contact investigation for people newly diagnosed with tuberculosis (TB) is poorly implemented, particularly in low- and middle-income countries. Conditional cash incentives may improve uptake.

Methods
We conducted a pragmatic, cluster-randomized, crossover trial of 2 TB contact investigation approaches (household-based and incentive-based) in 28 public primary care clinics in South Africa. Each clinic used 1 approach for 18 months, followed by a 6-month washout period, after which the opposite approach was used. Fourteen clinics were randomized to each approach. In the household-based arm, we conducted TB screening and testing of contacts at the household. In the incentive-based arm, both index patients and ≤10 of their close contacts (either within or outside the household) were given small cash incentives for presenting to study clinics for TB screening. The primary outcome was the number of people with incident TB who were diagnosed and started on treatment at study clinics.

Results
From July 2016 to January 2020, we randomized 28 clinics to each study arm, and enrolled 782 index TB patients and 1882 contacts in the household-based arm and 780 index patients and 1940 contacts in the incentive-based arm. A total of 1413 individuals started on TB treatment in the household-based arm and 1510 in the incentive-based arm. The adjusted incidence rate ratio of TB treatment initiation in the incentive- versus household-based arms was 1.05 (95% confidence interval: .97–1.13).

Conclusions
Incentive-based contact investigation for TB has similar effectiveness to traditional household-based approaches and may be a viable alternative or complementary approach to household-based investigation.
Novel histologic score predicts recurrent intestinal metaplasia after successful endoscopic eradication therapy
Authors: Triggs Joseph R , Krogh Katrina , Simon Violette , Krause Amanda , Kaplan Jeffrey B , Yang Guang-Yu , Wani Sachin , Kahrilas Peter J , Pandolfino John , Komanduri Srinadh 
Published: November 2022

Abstract
Endoscopic eradication therapy (EET) is an effective treatment for Barrett’s esophagus (BE); however, disease recurrence remains problematic requiring surveillance post-treatment. While data regarding predictors of recurrence are limited, uncontrolled reflux may play a significant role. Our aim was to develop a scoring system based on histopathologic reflux in surveillance biopsies following EET to identify patients at high risk for recurrence of BE. Patients were identified from two centers in the treatment with resection and endoscopic ablation techniques for BE consortium. Hematoxylin and eosin-stained slides of surveillance biopsies post-EET were assessed for histologic changes associated with reflux from a cohort of patients who also underwent pH-metry (derivation cohort). We developed a novel scoring system (Recurrent Epithelial Changes from Uncontrolled Reflux [RECUR]) composed of dilated intercellular spaces, epithelial ballooning, basal cell hyperplasia, and parakeratosis, to identify patients with abnormal esophageal acid exposure. This scoring system was then used to grade surveillance biopsies from patients with or without recurrence of BE following EET (validation cohort). Of 41 patients in the derivation cohort, 19.5% had abnormal acid exposure times (AET) while on proton pump inhibitor therapy. The mean (SD) RECUR score for patients with AET &lt;4% was 4.0 (1.6), compared with 5.5 (0.9) for AET ≥4% (P = 0.015). In the validation cohort consisting of 72 patients without recurrence and 64 patients with recurrence following EET, the RECUR score was the only significant predictor of recurrence (odds ratio: 1.36, 95% confidence interval: 1.10–1.69, P = 0.005). Histologic grading of surveillance biopsies using the RECUR scoring system correlates with BE recurrence following EET.