bluuebunny/crossref_metadata_2025_split huggingface dataset:
Middle phalanx epidermoid cyst, an unusual site: A case report
Authors: Makkar Dheeraj 
Published: April 2022

Epidermoid cysts are cutaneous cysts frequently observed among farmers, factory workers, carpenters, and tailors due to their occupations' predilection for repetitive minor hand trauma. A 66-year-old male laborer presented to our hospital with a swelling on the palmar aspect of his right middle finger. The swelling was accompanied by pain and an inability to work over the previous four months. A 2.5 cm × 2.5 cm smooth, tender, immobile, non-compressible hard swelling was detected just above the middle phalanx during the clinical examination on the volar aspect of the right middle finger. The diagnosis was confirmed by histopathology after excision. The patient's range of motion improved significantly following surgery, and his pain subsided. We present a novel location for an epidermal inclusion cyst and the importance of histopathologic evaluation in this case. Additionally, we emphasize the significance of extensively checking the cyst's epithelium to guarantee complete capsule removal and rule out any additional pathology.
The Linear and Nonlinear Indices of Electroencephalography Change in the Stroop Color and Word Test
Authors: Sobhani Vahid , Rezvani Zahra , Meftahi Gholam Hossein , Ghahvehchi-Hosseini Fahimeh , Hatef Boshra 
Published: April 2022

Introduction: This study evaluated the brain activity based on the linear and nonlinear features of surface electroencephalography (EEG) in the Stroop Color and Word Test (SCWT) and the effect of learning in the test response and related EEG features.Materials and Methods: A total of 21 women and 19 men with physical and mental health participated in this study. Four stages of this SCWT, consistently in the first and second stages and inconsistently in the third and fourth stages, were taken twice by the participants with a 10-min interval. Besides, EEG recording was simultaneously taken for 1 minute at each stage.Results: The number of correct responses in the inconsistent stages was lower than that in the consistent stages, while the delay of correct responses was more in the consistent stages. EEG features showed that the relative power band of alpha 1 (8-10 Hz) frequency reduced during the test compared to the resting state. In contrast, the gamma 2 (40-50 Hz) frequency band showed a significant increase. There was no significant difference between various stages of the test and between two repetitions in the test indices and EEG features.Conclusion: Compared to the resting state, the relative power of alpha 1 and gamma 2 frequency bands changed during SCWT without considering the stage of the test.
Effectiveness of the Combined Memory Training Program on Memory Skills and School Achievement of Children with Specific Learning Disorders: A Pilot Randomized Controlled Trial
Authors: Nazok Nasrin , Akbarfahimi Malahat , Ghaffari Amin , Parand Akram 
Published: April 2022

Introduction: Children with Specific Learning Disorders (SLD) suffer from some cognitive deficits affecting their school achievement. This study investigated the effect of the combined Working Memory Training Program (WMTP) with the Caillou program (the game-like features of computerized cognitive training programs) on memory (as a cognitive function) and academic achievement in children with SLD.Materials and Methods: In this pilot randomized controlled trial study, 30 children with SLD, aged 8-11 years, participated. They were randomly allocated to the intervention and control groups. The intervention group received 20 training sessions in 10 weeks, each lasting 30-45 minutes. The control group only participated in the assessment sessions. The primary outcome was verbal working memory skills assessed by the digit span and letter-number sequencing subtests of the Wechsler Intelligence Scale for Children, the fourth edition (WISC-IV). Also, the grades of science, literature, and mathematics were collected as the secondary outcomes. Children were assessed 3 times: baseline (pre-test), after the intervention (post-test), and 2 months after the intervention (follow-up).Results: Working memory (digit span and letter-number sequencing scores) and mathematics grades were significantly improved in the intervention group, as compared to the control group at the post-test session (P<0.05) and remained in the follow-up session.Conclusion: Although this combined program effectively improves working memory and mathematic grades, further research is suggested for more academic achievement.
Sagittal Spinal Mobility and Back Extensor Muscle Function in Older Females with Age-Related Hyperkyphosis
Authors: Roghani Tayebeh , Gladin Amy , Talebian Saeed , Khalkhali Zavieh Minoo , Niknam Hoda , Katzman Wendy B. 
Published: April 2022

Introduction: Spinal range of motion (ROM) is a potential and modifiable variable that may contribute to the maintenance of upright sagittal alignment. The present study aimed to compare spinal ROM in older females with and without hyperkyphosis and investigate associations between thoracic kyphosis and spinal ROM, back extensor strength (BES), and back extensor endurance (BEE).Materials and Methods: Sagittal spinal curvature and ROM were measured with the Spinal Mouse. Also, BES and BEE were assessed with a load cell. Variables were compared between older females with and without hyperkyphosis with the independent sample t test. We used the Pearson correlation coefficient to calculate associations between variables. Multiple linear regression was used to find which variable is best associated with kyphosis.Results: Lumbar and total spinal ROM were lower in the hyperkyphosis compared to the normal group (P<0.05). Thoracic kyphosis was associated with total lumbar ROM (r=-0.30, P=0.03), total spinal ROM (r=-0.35, P=0.01), BES (r=-0.73, P< 0.001), and BEE (r=-0.60, P< 0.001). Multiple linear regression analysis after adjusting for age, weight, and BMI showed that BES (P<0.001) and BEE (P=0.01) but not spinal ROM (P=0.16) were significantly associated with thoracic kyphosis.Conclusion: Females with hyperkyphosis had lower spinal ROM than those with normal kyphosis. While thoracic kyphosis was significantly associated with total lumbar ROM, total spinal ROM, BES, and BEE, multivariate regression showed that ROM was not a significant contributor to thoracic kyphosis. BES and BEE were significant contributors to thoracic kyphosis and should be targeted in the rehabilitation of hyperkyphosis.
Gait Abnormalities in a Patient with the Syndrome of Inappropriate Antidiuretic Hormone Secretion: A Case Studied with Gait Analysis
Authors: Luigi Di Lorenzo , Carmela Falzarano , Raimondo Cocozza , Paolo Marano , Vincenzo Golini , Itala Ventre 
Published: April 2022

Introduction: Hyponatremia, defined as serum sodium concentration <136 mEq/l, represents one of the most challenging clinical disorder in geriatric rehabilitative settings . It is associated with significant morbidity and mortality. Hyponatremia can be often followed by neurological symptoms caused by cerebral oedema and in severe hyponatremia, patients frequently experience balance disorder and a high risk of falls.Materials and Method: We report the case of a female patient, followed after an accurate diagnostic work-up for a syndrome of inappropriate antidiuresis (SIADH). Hyponatremia was initially treated with hypertonic saline infusion and then with fluid restriction. In consideration of the poor response to fluid restriction, treatment with tolvaptan was started. The patient experienced walking problems and was evaluated with an EMG computed Gait Analysis before and after that sodium level was normalized.Results: Gait analysis carried out highlighted neuromuscular instability with alteration of the time parameter and spatial postural deficit. Once corrected the hyposodiemia the patient showed a marked improvement in neuromuscular control with normalization of the temporal and spatial parameter of the step.Conclusions: The clinical manifestations of the patient with SIADH are related to the severity of hyponatremia and the speed with which the sodium deficit is established. The criteria for the diagnosis of SIADH in a patient with hypotonic hyponatremia remain those established by Bartter and Schwartz in 1967. Our suggestions is so to monitor balance and gait disorders and perform serial measurements of urine and serum osmolarity during rehabilitation process in order to prevent unbalance and falling.
Involvement of Epigenetics in the Pathogenesis, Testing and Management of Coronavirus Disease 2019 (COVID-19) Pandemic: A Narrative Review
Authors: Yahaya Tajudeen , Oladele Esther , Muhammed Aminu , Haruna Abdulhakeem , Liman Usman 
Published: April 2022

Background: There is an intense search for the Coronavirus Disease 19 (COVID-19) cure, to stem the spread and burden of the disease worldwide. Studies revealed that epigenetic modifications impact the pathogenesis of some COVID-19 cases, which can be used as therapeutic targets.
Objectives: This review articulated the role of epigenetics in the pathogenesis and management of COVID-19.
Methods: Relevant articles published between January 2000 and November 2020 were retrieved from reputable academic databases, including PubMed, SpringerLink, Scopus, and Google Scholar.
Results: Epigenetic modifications in the COVID-19’s pathogen, called the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and host’s cells may influence susceptibility or resistance to the disease. Notably, abnormal Deoxyribonucleic Acid (DNA) methylation and histone modification involving immune regulatory genes and molecules, such as cytokines and interferon-regulated genes may compromise immune function and enhance the host’s susceptibility and disease severity. The hypomethylation of SARS-CoV-2’s receptor, called the Angiotensin-Converting Enzyme 2 (ACE2), causing its overexpression, can also enhance SARS-CoV-2’s infectivity. Moreover, SARS-CoV-2 can hijack the host’s MicroRNA (miRNA) using its miRNA and compromise the immune function, increasing its infectivity. Fortunately, epigenetic changes are reversible; thus, a therapy that targets the epigenetic changes in the affected case may reverse COVID-19.
Conclusion: Modifications in the SARS-CoV-2 or host epigenome promote the pathogenesis and severity of COVID-19. Epigenetic changes are reversible, so healthcare providers are advised to formulate therapeutic procedures that target the causal mechanisms in the affected individual.
In vivo Toxicity Evaluation of Ethanolic Extract From Two Mangrove Plants
Authors: Aunjum Afiya , Biswas Rana , Al Munna Abdullah , Billah Morsaline , Islam Emdadul , Didarul Islam Kazi Mohammed 
Published: April 2022

Background: Mangrove plants, often possessing a unique collection of metabolites, have extensively been used for the primary healthcare of coastal residents.
Objectives: To determine the safety level and enrich the scientific data, the present study aimed to investigate the toxicity of Avicennia officinalis and Excoecaria agallocha.
Methods: Ethanolic leaf and stem extracts were evaluated for cytotoxicity by brine shrimp lethality assay. The obtained extracts were administered to Swiss albino in a single dose (200, 400, 800, 1600, & 3200 mg/kg body weight) by oral-gavage for acute toxicity assay. Furthermore, systematic observation was performed by close monitoring for any toxic manifestations and mortality after dosing for the first 4 h, at 24 h and twice daily for 6 days. Evaluating the adverse effects were estimated by comparing the test groups with the controls. After sacrificing all group animals, relative organ weight was measured and histopathological analysis was conducted.
Results: Having Lethal Concentration (LC50) of 44.66 µg/mL, E. agallocha leaf was found with the highest toxicity against brine shrimp nauplii. The toxicological study data demonstrated no death and noticeable change in behavioral patterns in the test mice groups, compared with the control group. Moreover, no significant (P>0.05) differences were found in body weight and relative organ weights, compared to the controls. The histological structures of the liver in the treated mice displayed regular tissue configurations similar to the control group.
Conclusion: In this study, the mice model exhibited no harmful effects; thus, the reported results indicated that the ethanolic extracts of leaf and stem of these two mangrove plants are safe for therapeutic use. Further long-term toxicological impact of the extracts should be determined for well-founded confirmation.
Sudden Death Due to Acetone Toxicity
Authors: Mohammadzadeh Hasan , Mohammadi Hamidreza , Tavakoli Mohammad Ali , Sadeghi Sajjad 
Published: April 2022

Background: Acetone or propanone is a volatile liquid that can be absorbed by ingestion, inhalation, and dermal routes, and is distributed throughout the body.
Case Presentation: This study presented a case of an employee of the Emergency Medical Center of North Khorasan Province, Iran, who died due to acetone poisoning. He was last seen alive approximately 4 hours before his body was found. Thus, the deceased was found 4 hours after death. He was a 25-year-old unmarried male nurse. He had a history of smoking for the last 4 years and reported diarrhea and nausea on the day before death. There was no history of diabetes or alcoholism as well as no other definite causes. According to interviews with his colleagues and family, he had no history of depression. A postmortem examination was performed to define the cause of death. Postmortem quantitative toxicological analysis with Gas Chromatography with Flame-Ionization Detection (GC-FID) presented acetone in the vitreous (35 mg/dL), blood (28 mg/dL), and urine (77 mg/dL) samples. Furthermore, in postmortem pathological analysis, highly microvascular changes and the diffuse necrosis of hepatocytes were reported. Other pathological changes in the brain and lungs were observed. No other definite medical cause of death was found. The cause of death was determined to be acute acetone intoxication.
Conclusion: Contrary to public opinion, acetone is a toxic and dangerous substance; thus, it is necessary to improve and implement public safeguards concerning acetone usage, as well as its handling, and disposal. Organ toxicity due to acetone can be a major cause of death. Other alcohol-related poisoning deaths, such as acetone and other metabolites, should be considered.
Lacunar Infarction In Old Stroke: A Case Report
Authors: Devantoro Mohammad Ridho , Wijaya Wilson Saputra , Arigi Putra Muhammad Iqbal , Yogaswara Raden 
Published: April 2022

Introduction: Lacunar stroke accounts for nearly a quarter of all ischemic strokes and is an important cause of vascular cognitive impairment and dementia.
Case Presentation: A 52-year-old man with lacunar infarct presented with weakness in his left thumb and forefinger since one day ago when he was sitting down. The patient’s fingers appear bent as if holding a pencil and could not be straightened. Physical examination showed an high blood pressure, and paresis of the right facial and hypoglossal nerve. A non-contrast CT scan of head using the parenchymal window showed a hypodense lesion on the left pons, interpreted as a lacunar infarct.
Discussion: Lacunar strokes represent approximately 25% of ischemic strokes and most are associated with good outcomes. However, in 20% to 30% of patients with lacunar stroke, early neurologic damage occurs within the first days after stroke onset. Lacunar stroke was defined as acute lacunar syndrome with infarction <15 mm in diameter in the basal ganglia, deep white matter, thalamus or pons that is not associated with large vessel atherosclerosis or a cardioembolic source.
Conclusion: Lacunar infarction is a potentially reversible. These conditions can potentially be well managed with adequate treatment.
O papel da Filosofia na formação do(a) cientista da Educação
Authors: Cardoso Alves Daniel 
Published: April 2022

Este artigo se constitui metodologicamente como uma revisão de literatura e tem como objetivo geral evidenciar o papel da Filosofia na formação do pedagogo, o cientista da Educação. Para tanto, parte da seguinte questão central: qual o papel da Filosofia na formação do(a) cientista da Educação? Ancorando-se em uma literatura que concebe a Educação em sua dimensão filosófico-científica, tece considerações importantes acerca do conceito de Educação, Ciência, Filosofia, Pedagogia e Pedagogo. Dentre os seus achados, destaca-se a constatação de que a Filosofia vem sendo inserida nos currículos dos cursos de Pedagogia do Brasil de forma panorâmica e pouco aprofundada, o que repercute, inevitavelmente, no conceito de Educação que prevalecerá entre os pedagogos. Como principal contribuição, a discussão exposta evidencia a importância da inseparabilidade entre Filosofia e Ciência para a formação integral do pedagogo, sobretudo no que diz respeito à compreensão radical do seu objeto de estudo e campo de atuação, defendendo, para tanto, que sem Filosofia, muito facilmente, o pedagogo tenderá a tornar-se um profissional que executa práticas e reproduz teorias, porém, pouco sobre ela pensa.
The Influence of TAM, Social influence, Security Relationship toward Intention to Use E Wallet through Attitude and Trust
Authors: Nisa Ulfa Khoirun , Solekah Nihayatu Aslamatis 
Published: April 2022

The purpose of this study is to examine relationship of TAM, Social Influence and Security Toward Intention to use (IU) E-wallet with attitude and trust as intervening variables. The research uses quantitative approach with survey approach. The population of this survey is the people who live in Malang City with the conditions that they are 19-34 years old and the e-wallet used is (Gojek, OVO, Dana, LinkAja, Jenius). The samples taken was 150 respondents. The analysis technique used was SEM-PLS. The results showed that PU, SI, and S had no influence on IU e-wallets, only PEU had direct influence on IU e-wallets, Attitude could not mediate PU and PEU on IU e-wallet, but Trust could fully mediate Security against IU. This showed that the security of using the system can influence respondents' intention to use e-wallets based on trust in the system and it is recommended that e-wallet providers always pay attention to the security of their systems and simplify their applications so that users can benefit from using them.
Croissance et Decroissance d’une Ville en Phase de Desurbanisation : Le Cas de Mossendjo en Republique du Congo
Authors: Mambou Jean-Romuald , Elenga Hilaire 
Published: April 2022

Cet article traite d’un phénomène urbain encore méconnu en Afrique, mais qui est fréquent ailleurs, à savoir la décroissance des villes. En effet, ce phénomène s’est fortement développé depuis les années 1990 dans plusieurs régions du monde. Les villes en décroissance sont celles qui perdent leurs populations qui migrent en direction d’autres villes plus attractives, à cause du déclin de l’emploi local, des problèmes sociaux et de la faiblesse de l’économie locale. Ce phénomène peut toucher des villes de toutes tailles et causé une crise structurelle multidimensionnelle. Notre enquête sur Mossendjo a conclu que cette ville, de taille moyenne dans l’armature urbaine congolaise, est depuis plusieurs années en phase de décroissance l’entraînant inexorablement vers sa ruralité et la pauvreté de sa population. Elle a démontré que cette décroissance est due essentiellement à la désindustrialisation et la désurbanisation de la ville : la part de la population vivant de l’agriculture de subsistance atteint aujourd’hui 90%, la structure de l’emploi montre que 79% de la population de Mossendjo est sans emploi, la ville compte 56,52% de femmes et sa population est relativement jeune, 92,65% de la population a moins de 45 ans et 75% des habitants de la ville de Mossendjo est au chômage.

This article deals with an urban phenomenon still little known in Africa, but which is frequent elsewhere, namely the decline of cities. Indeed, this phenomenon has developed strongly since the 1990s in several regions of the world. Shrinking cities are those who lose their populations who migrate to other more attractive cities, because of the decline of local employment, social problems and the weakness of the local economy. This phenomenon can affect cities of all sizes and cause a multidimensional structural crisis. Our survey of Mossendjo concluded that this city, of medium size in the Congolese urban framework, has been in a phase of decline inexorably towards its rurality and the poverty of its population. It demonstrated that this decline is essentially due to deindustrialization and de-urbanization of the city: the share of the population living from subsistence agriculture today reaches 90%, the employment structure shows that 70% of the population of Mossendjo is unemployed, the city has 56.52% of women and its population is relatively young, 92.65% of the population is under 45 years old and 75% of the inhabitants of the town of Mossendjo are unemployed.
Effet d’un Programme de Développement des Compétences Psychosociales par la Régulation des Émotions sur la Diminution du Comportement Hostile chez des Avocats Tunisiens
Authors: Riahi Molka 
Published: April 2022

L’objectif de cette étude est d’évaluer l’effet d’un programme thérapeutique de développement des compétences psychosociales (émotivocognitivo-comportemental) sur la diminution du comportement hostile et la capacité de régulation des émotions chez des avocats adhérents à l’association Tunisienne de fierté et dignité. Cette adhésion nous a permis de trouver un échantillon accessible au travail. L’échantillon de l’étude comptait 120 avocats ayant un degré élevé d’hostilité selon le questionnaire de l’hostilité, âgés de 25 à 60 ans. Les participants ont été randomisés dans un programme de vingt-deux séances de 120 minutes de psychothérapie basée sur la régulation du comportement hostile avec ses différentes composantes (émotionnelles, cognitives et comportementales). Les participants du groupe témoin n’ont pas participé au programme. La mesure principale était d’évaluer le programme de développement des compétences psychosociales (variable indépendante), le comportement hostile (variable dépendante, évaluée par l’échelle d’Hostilité et la capacité de régulation des émotions (variable médiatrice). Les principaux effets du programme proposé dans cette étude étaient efficaces. Les séances ont permis de contrôler et de diminuer significativement le comportement hostile, ainsi que d’améliorer la capacité de régulation des émotions chez les avocats participants à la recherche.

This paper focuses on assessing the effect of a therapeutic program for the development of psychosocial (emotional-cognitive-behavioral) skills on the decrease in hostile behavior and the capacity for regulating emotions in lawyers adhering to the Tunisian association of pride and dignity. The study population consisted of 120 lawyers with a high degree of hostility, according to the hostility questionnaire, aged 25 to 60 years. The participants were randomized into a program of twenty-two 120-minute sessions of psychotherapy based on the regulation of hostile behavior with its different components (emotional, cognitive and behavioral). Participants in the control group did not participate in the program. The primary measure was to assess the treatment program (independent variable) and hostile behavior (dependent variable) using the Hostility scale. Secondary measures consisted of mediating variables such as psychosocial skills assessed by the psychosocial skills questionnaire. The main effects of the psychotherapeutic program, proposed in this study, indicate that the sessions of the program make it possible to control. It significantly decreases hostile behavior and also helps to improve the capacity of emotion regulation in the lawyers participating in this study.