bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Super-Resolution Altitude Measurement Technology for VHF Radar Based on Synthetic Steering Vector and Model Matching
Authors: Le Yi , Tang Ji , Huang Qiang , Guan Linhai , Zhou Jianyang , Dong Xiaoxuan 
Published: November 2022

Abstract
As radar is a kind of measuring device, the altitude measuring accuracy is a quite important core tactical indicator. In engineering practice, the altitude measuring accuracy deteriorates significantly in low elevation range, especially for low frequency radar such as VHF radar. This urgent problem to be solved is what we focus on in this article. After building a multipath reflection model, a method of altitude super-resolution measurement based on synthetic steering vector and model matching is proposed. Then some simulation analysis is finished, and some validation experiments are carried out on a practical VHF radar prototype. The results of theoretical simulation and prototype experiments show obviously improved altitude measuring performance compared with traditional measuring methods, verifying the correctness and engineering feasibility of the super-resolution altitude measurement technology proposed in this article. This study should have certain practical guiding significance for the theoretical and application research of related fields.
Simulation of Special Distribution of energy of plasma in a High-speed Changing Magnetic Field
Authors: Wei Xijie 
Published: November 2022

Abstract
Tokamak and inertial confinement fusion(ICF) are two kinds of devices to achieve fusion. Magnetic and gravitational fields are the drivers used in tokamak and ICF, respectively. In other fusion devices like MIF, both of them are used. In this work, different from these fusion devices mentioned above, a new promising method to confine plasma is proposed. Spacial distribution of energy of plasma in a high-speed changing magnetic field is simulated. This method is expected to achieve fusion.
Developability assessment at early-stage discovery to enable development of antibody-derived therapeutics
Authors: Zhang Weijie , Wang Hao , Feng Nan , Li Yifeng , Gu Jijie , Wang Zhuozhi 
Published: November 2022

Abstract
Developability refers to the likelihood that an antibody candidate will become a manufacturable, safe and efficacious drug. Although the safety and efficacy of a drug candidate will be well considered by sponsors and regulatory agencies, developability in the narrow sense can be defined as the likelihood that an antibody candidate will go smoothly through the chemistry, manufacturing and control (CMC) process at a reasonable cost and within a reasonable timeline. Developability in this sense is the focus of this review. To lower the risk that an antibody candidate with poor developability will move to the CMC stage, the candidate’s developability-related properties should be screened, assessed and optimized as early as possible. Assessment of developability at the early discovery stage should be performed in a rapid and high-throughput manner while consuming small amounts of testing materials. In addition to monoclonal antibodies, bispecific antibodies, multispecific antibodies and antibody-drug conjugates, as the derivatives of monoclonal antibodies, should also be assessed for developability. Moreover, we propose that the criterion of developability is relative: expected clinical indication, and the dosage and administration route of the antibody could affect this criterion. We also recommend a general screening process during the early discovery stage of antibody-derived therapeutics. With the advance of artificial intelligence-aided prediction of protein structures and features, computational tools can be used to predict, screen and optimize the developability of antibody candidates and greatly reduce the risk of moving a suboptimal candidate to the development stage.
Can native predators be used as a stepping stone to reduce prey naivety to novel predators?
Authors: Van der Weyde Leanne K , Blumstein Daniel T , Letnic Mike , Tuft Katherine , Ryan-Schofield Ned , Moseby Katherine E 
Published: November 2022

AbstractPredator naivety negatively affects reintroduction success, and this threat is exacerbated when prey encounters predators with which they have had no evolutionary experience. While methods have been developed to inculcate fear into such predator-naïve individuals, none have been uniformly successful. Exposing ontogenetically- and evolutionary-naïve individuals first to native predators may be an effective stepping stone to improved responses to evolutionarily novel predators. We focused on greater bilbies (Macrotis lagotis) and capitalized on a multi-year mammalian recovery experiment whereby western quolls (Dasyurus geoffroii) were reintroduced into parts of a large fenced reserve that contained a population of naïve bilbies. We quantified a suite of anti-predator behaviors and measures of general wariness across quoll-exposed and quoll-naive bilby populations. We then translocated both quoll-exposed and quoll-naïve individuals into a large enclosure that contained feral cats (Felis catus) and monitored several behaviors. We found that bilbies can respond appropriately to quolls but found only limited support that experience with quolls better-prepared bilbies to respond to cats. Both populations of bilbies rapidly modified their behavior in a similar manner after their reintroduction to a novel environment. These results may have emerged due to insufficient prior exposure to quolls, inappropriate behavioral tests, or insufficient predation risk during cat exposure. Alternatively, quolls and cats are only distantly related and may not share sufficient similarities in their predatory cues or behavior to support such a learning transfer. Testing this stepping stone hypothesis with more closely related predator species and under higher predation risk would be informative.
Barbeques and shiny numbers: micro-ethical encounters in Sydney social housing estates
Authors: Massola Cate , Howard Amanda 
Published: November 2022

AbstractMicro-ethical practices are at the heart of community development work, however they are often subsumed within descriptions and reports focused on projects and outcomes. In this article, we examine the critical role played by micro-ethical practices in addressing exclusion and misrecognition with community members experiencing social disadvantage. In three vignettes drawn from a weekly food and social support programme, we discuss the ways in which micro-ethical practices in community development can address exclusion at a fundamental level in the everyday environment using relation-based principles and a framework of recognition.
The Association Between Prebooster Vaccination Antibody Levels and the Risk of Severe Acute Respiratory Syndrome Coronavirus 2 Infection
Authors: Barda Noam , Canetti Michal , Gilboa Mayan , Asraf Keren , Indenboim Victoria , Weiss-Ottolenghi Yael , Amit Sharon , Zubli Daniel , Doolman Ram , Mendelson Ella , Freedman Laurence S , Kreiss Yitshak , Lustig Yaniv , Regev-Yochay Gili 
Published: November 2022

AbstractThe correlation between anti–severe acute respiratory syndrome coronavirus 2 antibody levels and infection was reported. Here, we estimated the role of pre–fourth dose levels using data from 1098 healthcare workers. The risk of infection was reduced by 46% (95% confidence interval, 29%–59%) for each 10-fold increase in prebooster levels. Prebooster antibody levels could be used to optimally time boosters.
Renal arcuate vein thrombosis–induced acute kidney injury: a rare multiple-Hit–mediated disease
Authors: Pardinhas Clara , Filipe Rui , Vergnaud Paul , Grapin Mathilde , Ferrière Elsa , Jamet Anne , Fourgeaud Jacques , Da Rocha Nicolas , Pérot Philippe , Boyer Olivia , Rabant Marion , Van Huyen Jean-Paul Duong , Isnard Pierre 
Published: November 2022

ABSTRACT

Background
Renal arcuate vein thrombosis (RAVT) is a rare and recently recognized cause of acute kidney injury (AKI) in young adults. However, the precise incidence and underlying pathophysiologic mechanisms leading to AKI in these patients remain elusive.

Methods
This study included all patients who underwent a kidney biopsy over a 40-month period sent to the pathology department of Necker-Enfants Malades Hospital, with evidence of RAVT. We performed coagulation tests, genetic testing for thrombophilia, complete urine toxicologic screening and kidney metagenomic sequencing to identify an underlying cause of thrombosis.

Results
We report five pediatric cases of RAVT discovered on kidney biopsy performed in the setting of unexplained AKI. Investigations did not reveal an underlying cause of thrombosis but only a significant nonsteroidal anti-inflammatory drugs (NSAIDs) use was reported in 4/5 patients, supporting a potential link between NSAIDs use and RAVT. By performing metagenomic sequencing on kidney biopsy samples, we detected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in the kidney of one patient. These results suggest that systemic SARS-CoV-2 infection may also be a key contributing factor of renal thrombosis, particularly by inducing potential endothelial disruption.

Conclusions
In conclusion, RAVT-induced AKI appears to be a multiple hit–mediated disease in which NSAIDs consumption and viral infection such as SARS-CoV-2 may be crucial contributing factors. These findings may have significant public health implications given the prevalence of NSAIDs use in the general population. Increased awareness and additional study of future cases may lead to a better understanding of this rare cause of AKI in children and young adults.
FDRdb: a manually curated database of fibrotic disease–associated RNAome and high-throughput datasets
Authors: Wang Chengyu , Chen Tingting , Mu Yuchen , Liang Xuan , Xiong Kai , Ai Liqiang , Gu Yunyan , Fan Xingxing , Liang Haihai 
Published: November 2022

Abstract
Fibrosis is a common and serious disease that exists as a complicated impairment in many organs and triggers a complex cascade of responses. The deregulation of Ribonucleic Acids (RNAs) plays important roles in a variety of organ fibrosis cases. However, for fibrotic diseases, there is still a lack of an integrated platform with up-to-date information on RNA deregulation and high-throughput data. The Fibrotic Disease–associated RNAome database (FDRdb) (http://www.medsysbio.org/FDRdb) is a manually curated database of fibrotic disease–associated RNAome information and high-throughput datasets. This initial release (i) contains 1947 associations between 912 RNAs and 92 fibrotic diseases in eight species; (ii) collects information on 764 datasets of fibrotic diseases; (iii) provides a user-friendly web interface that allows users to browse, search and download the RNAome information on fibrotic diseases and high-throughput datasets and (iv) provides tools to analyze the expression profiles of fibrotic diseases, including differential expression analysis and pathway enrichment. The FDRdb is a valuable resource for researchers to explore the mechanisms of RNA dysregulation in organ fibrosis.
Database URL: http://www.medsysbio.org/FDRdb
High complication rate with titanium plates for chest wall reconstruction following tumour resection
Authors: Bergovec Marko , Smolle Maria , Lindenmann Jörg , Fediuk Melanie , Leithner Andreas , Smolle-Jüttner Freyja-Maria 
Published: November 2022

Abstract

OBJECTIVES
The reconstruction of the chest wall defect after tumour resection presents a challenge. Titanium rib plates were presented as a reconstruction option due to its biocompatibility, flexibility and pliability. The aim of this study was to evaluate the outcome of single-centre cohort treated with chest wall reconstruction after tumour resections, with a focus on the titanium rib plates reconstruction.

METHODS
We retrospectively reviewed the data of 26 patients who underwent wide resection for malignancies of the chest wall, where reconstruction was performed using polypropylene mesh, porcine dermal collagen mesh with or without titanium rib plates, operated on between 2012 and 2019. Events being associated with the surgery requiring revision were rated as complications.

RESULTS
Most of the patients had primary tumours (n = 19; 73%). A mean of 3.7 ribs (range: 1–7) was resected. Reconstruction was performed with titanium rib plates (13 patients, 50%), of these 11 were performed with additional mesh grafts. The remaining 13 patients (50%) underwent reconstruction with mesh grafts only. Fourteen patients (54%) developed a complication requiring surgical revision, after a median of 5.5 months. The most common complication was wound healing deficit (n = 4), plate fracture (n = 2), mesh rupture (n = 2), infection (n = 2) and local recurrence (n = 2). The only factor being associated with the development of complications was the usage of a plate (P = 0.015), irrespective of defect size (P = 0.29).

CONCLUSIONS
The high complication rate is found when using titanium plates for chest wall reconstruction after tumour resection. A high caution is recommended in choosing the chest wall reconstruction method.
Development of a health-promoting sports club’s intervention in France applying participatory action research
Authors: Tezier Benjamin , Guillemin Francis , Vuillemin Anne , Johnson Stacey , Lemonnier Fabienne , Rostan Florence , Van Hoye Aurélie 
Published: November 2022

AbstractThe recognition of sports clubs (SC) as health-promoting settings is increasing, as well as the number of health promotion (HP) interventions implemented in this setting. However, minimal understanding of their development process and the persistent gap between theoretical knowledge and real-life practice is a major limitation to their implementation. This article describes a participatory research approach, implicating 29 stakeholders in sports and HP (6 HP researchers, 9 HP professionals, 6 representatives from regional and national sports organizations and 8 representatives from SC), leading to the co-construction of a health-promoting SC intervention. Stakeholders were mobilized through four stages: (i) analysis of effective programs, (ii) co-construction workshops, (iii) evaluation of relevance and acceptability, and (iv) beta-testing of a massive open online course (MOOC). A qualitative analysis was carried out on data collected through notetaking, recordings, transcripts, email exchanges and produced documents. This work led to the development of an HP intervention, including an MOOC, as well as a seven-step SC-tailored program. The convergence of theoretical knowledge and contextual real-life practice made it possible to respond to the specific needs and implementation problems encountered by SC actors and to develop acceptable strategies and tools.
Examining COVID-19 vaccine attitude using SEM-Artificial Neural Networks approach: a case from Reddit community
Authors: Sun Yao , Hamedani Moez Farokhnia , Javidi Giti , Sheybani Ehsan , Hao Feng 
Published: November 2022

Summary
As new coronavirus variants continue to emerge, in order to better address vaccine-related concerns and promote vaccine uptake in the next few years, the role played by online communities in shaping individuals’ vaccine attitudes has become an important lesson for public health practitioners and policymakers to learn. Examining the mechanism that underpins the impact of participating in online communities on the attitude toward COVID-19 vaccines, this study adopted a two-stage hybrid structural equation modeling (SEM)-artificial neural networks (ANN) approach to analyze the survey responses from 1037 Reddit community members. Findings from SEM demonstrated that in leading up to positive COVID-19 vaccine attitudes, sense of online community mediates the positive effects of perceived emotional support and social media usage, and perceived social norm mediates the positive effect of sense of online community as well as the negative effect of political conservatism. Health self-efficacy plays a moderating role between perceived emotional support and perceived social norm of COVID-19 vaccination. Results from the ANN model showed that online community members’ perceived social norm of COVID-19 vaccination acts as the most important predictor of positive COVID-19 vaccine attitudes. This study highlights the importance of harnessing online communities in designing COVID-related public health interventions and accelerating normative change in relation to vaccination.
Vales+Tú: a cluster-randomized pilot study to reduce workplace injuries among US Latino day laborers
Authors: Fernández-Esquer Maria Eugenia , Atkinson John S , Hernandez Rodrigo A , Aguerre Cecilia F , Brown Louis D , Reininger Belinda , Ojeda Martha A , Field Craig , Rhoton Jayson M , Da Silva Cristina Espinosa , Diamond Pamela M 
Published: November 2022

Summary
Latino day laborers (LDL) are a vulnerable population of workers facing considerable risk for occupational injury. Under the guidance of our Community Advisory Board, we developed and tested the feasibility, acceptability and preliminary effects of Vales+Tú (You Are Worth More), a workplace injury risk-reduction program implemented by promotores on street-corners where LDL seek employment. The program was informed by theoretical perspectives emphasizing individual and group agency and self-determination. A pilot three-arm cluster-randomized community trial was conducted among 75 LDL. The intervention arms consisted of an individualized Brief Motivational Interview, a Group Problem Solving activity and a standard of care control (OSHA safety cards). We met our study goal of 25 LDL per intervention arm, and contacted 88% of participants post intervention. Participants evaluated the interventions favorably. At post-test, the Brief Motivational Interview group reported significant reductions in exposure to workplace hazards and increases in risk-reduction practices. The Group Problem Solving participants showed significant reductions in exposure to hazards (t-test −4.16, p &lt; 0.001). Both intervention groups increased their reliance on corner peers, a measure of social support. Standard of care participants increased in self-efficacy to work safely. Overall, the only significant different between the three study conditions was in self-efficacy. These findings provide evidence of the feasibility and acceptability of Vales+Tú and show preliminary program efficacy. A large-scale replication trial will permit a more formal modeling of the study findings. Clinical Trial Registration (ClinicalTrials.gov): NCT04378348.
A teacher professional development programme to enhance students’ critical health literacy through school-based health and physical education programmes
Authors: Peralta Louisa R , Cinelli Renata L , Marvell Claire L , Nash Rosie 
Published: November 2022

SummaryHealth literacy is a critical asset for adolescents to develop given its positive impact on health outcomes. The few studies that have targeted teacher knowledge and attitudes show that teachers themselves find it difficult to: navigate the multi-modal nature of health information; critically evaluate the different modes and texts; and apply health-related information in a variety of contexts. This research study aimed to address this issue through developing and implementing a teacher professional development (PD) programme for three Australian secondary schools and nine Health and Physical Education (HPE) teachers to improve health literacy, particularly critical health literacy, content and pedagogies embedded in current HPE programmes. Fifteen HPE programmes were analysed using Nutbeam’s health literacy hierarchy and the Australian Curriculum: HPE outcomes and content, with this analysis informing a personalized PD programme. To evaluate how teachers experienced the personalized PD programme, interviews conducted at the completion of the PD programme were analysed using Braun and Clarke’s thematic approach. According to the teachers, the PD had improved their knowledge and understanding of the three levels of HL, including how to implement it into their practice. The personalized nature was a key strength of the PD programme as it allowed for changes to be made in a time-efficient manner, a known challenge for teachers. Teachers recommended the provision of additional resources that foster students’ critical health literacy levels and an additional session to ensure sustainable changes in planning and teaching practices.
Impact of a community-based diabetes self-management support program on adult self-care behaviors
Authors: Dietz C J , Sherrill W W , Ankomah S , Rennert L , Parisi M , Stancil M 
Published: November 2022

Abstract
Diabetes is a chronic condition that has reached epidemic proportions in the United States, affecting nearly 34 million adults, and disproportionately affecting vulnerable populations, such as ethnic minorities, the elderly and individuals with low socioeconomic status. This study addresses the impact of the Health Extension for Diabetes (HED) program, a community-based diabetes self-management support program, on adult diabetes self-care behaviors. The Summary of Diabetes Self-Care Activities (SDSCA) was utilized to evaluate improvement in diabetes self-care behaviors. Descriptive statistics, univariate and multivariable regression models were conducted. Significant increases were observed among program participants (N = 149) in all five subscales of the SDSCA (general diet, specific diet, blood glucose testing, exercise and foot care; P-values &lt; 0.001). A priority of this diabetes education program was helping underserved populations; over half (62%) of participants self-identified as Black/African Americans. After program participation, scores on all SDSCA subscales increased significantly among Black/African Americans (n = 93) by approximately 1 day per week. White/other races (n = 56) showed similar increases in four of the SDSCA subscales post-HED program participation. This study shows that increasing participation in community-based, diabetes self-management support programs, such as HED, can increase engagement in diabetes self-care behaviors among underserved groups.