bluuebunny/crossref_metadata_2025_split huggingface dataset:
Male pelvic pain: the role of psychological factors and sexual dysfunction in a young sample
Authors: Edvinsson Magnus , Karlsson Moa , Linton Steven J. , Brattgård Klas , Solinger Gabriel , Flink Ida K. 
Published: July 2022

Abstract

Objectives
Male pelvic pain is a common yet poorly understood condition, strongly influencing quality of life of those affected. Research on psychological and sexual factors is lacking, specifically on younger men in family-forming ages. This study aims to explore psychological and sexual factors related to pelvic pain in younger men (<40 years) through a cross-sectional design.

Methods
Participants were recruited via social media, and completed a digital survey regarding sexual health and psychological distress (n=2,647). Men with varying levels of pelvic pain were compared on levels of psychological distress and self-reported sexual health.

Results
Men with pelvic pain (n=369) reported significantly higher levels of catastrophizing, anxiety and premature ejaculation compared to men without pelvic pain. Furthermore, men with higher pain intensity reported significantly higher levels of catastrophizing, anxiety and depressive symptoms compared to men experiencing lower pain intensity. Hierarchical regression analysis revealed catastrophizing and depressive symptoms as significantly predictors of pain intensity.

Conclusions
These findings underscore the role of psychological factors in male pelvic pain, and points to the need for integrating a psychological understanding for further treatment development.
Multiple sluicing and islands: a cross-linguistic experimental investigation of the clausemate condition
Authors: Cortés Rodríguez Álvaro 
Published: July 2022

AbstractThis paper experimentally investigates the two generalizations for multiple sluicing (MS) recently presented by Klaus Abels and Veneeta Dayal: first, that wh-remnants must have clausemate correlates in the antecedent utterance and, second, that wh-remnants in MS can have correlates in the antecedent clause that are contained in a strong syntactic island. The fact that MS displays both of these properties is puzzling since island insensitivity under sluicing favors a non-sententialist approach to MS, while the clausemate requirement on MS is most straightforwardly explained by postulating a silent structure at the ellipsis site. Even though the clausemate condition has been reported in several languages, no experimental work has been conducted so far to examine its precise effects on the acceptability of MS constructions. In this paper, I will present the results of a series of experiments in German, English, and Spanish (employing both acceptability judgment tasks and a self-paced reading task), where the factors of clausemateness and islandhood have been examined systematically. The results provide solid cross-linguistic support for Abels and Dayal’s generalizations by showing that multiple sluices originating from islands and non-islands are equally acceptable and do not exhibit online processing differences. Furthermore, the acceptability judgment tasks show a significant degradation in acceptability when the correlates in the antecedent do not stem from the same finite clause, thus violating the clausemate condition. I will interpret these results as supporting a particular strand of sententialist research known as theisland evasionapproach and, in particular, defend that MS is derived from a non-isomorphicshort sourcesluice.
Gestational Buprenorphine Exposure Disrupts Dopamine Neuron Activity and Related Behaviors in Adulthood
Authors: Elam Hannah B. , Donegan Jennifer J. , Hsieh Jenny , Lodge Daniel J. 
Published: July 2022

AbstractOpioid misuse among pregnant women is rapidly increasing in the United States. The number of maternal opioid-related diagnoses increased by 131% in the last 10 years, resulting in an increased number of infants exposed to opioidsin uteroand a subsequent increase in infants developing neonatal abstinence syndrome (NAS). The most prescribed treatment to combat maternal opioid use disorder is buprenorphine, a partial μ-opioid receptor agonist and κ-opioid receptor antagonist. Buprenorphine treatment effectively reduces NAS but has been associated with disrupted cortical development and neurodevelopmental consequences in childhood. Less is known about the long-term neurodevelopmental consequences following buprenorphine exposurein utero. Previous research has shown that gestational buprenorphine exposure can induce anxiety-like and depressive-like phenotypes in adult rats, suggesting that exposure to buprenorphinein uteromay render individuals more susceptible to psychiatric illness in adulthood. A common pathology observed across multiple psychiatric illnesses is dopamine system dysfunction. Here, we administered the highly-abused opioid, oxycodone (10 mg/kg, i.p.) or a therapeutic used to treat opioid use disorder, buprenorphine (1 mg/kg, i.p) to pregnant Sprague Dawley rats from gestational day 11 through 21, then examined neurophysiological alterations in the mesolimbic dopamine system and dopamine-dependent behaviors in adult offspring. We found that gestational exposure to buprenorphine or oxycodone increases dopamine neuron activity in adulthood. Moreover, prenatal buprenorphine exposure disrupts the afferent regulation of dopamine neuron activity in the ventral tegmental area (VTA). Taken together, we posit that gestational buprenorphine or oxycodone exposure can have profound effects on the mesolimbic dopamine system in adulthood.
Redox-sensitive DJ-1 protein: an insight into physiological roles, secretion, and therapeutic target
Authors: Dash Biplab Kumar , Urano Yasuomi , Saito Yoshiro , Noguchi Noriko 
Published: July 2022

Graphical abstract

Abstract
The highly conserved DJ-1 protein fundamentally acts as a redox sensor conferring antioxidative cytoprotection under oxidative insults. DJ-1 preferentially undergoes oxidation at 106 cysteine residue (C106) under oxidative stress. Although initially identified as an oncogene, emerging evidence suggests the essential roles of DJ-1 in modulating numerous physiological processes involved in cellular growth, development, survival, and death. Compromised DJ-1 expression and function directly or indirectly trigger signaling cascades leading to pathophysiological conditions including neurodegeneration, cancer, stroke, and inflammatory diseases. Besides the intracellular functions, enhanced DJ-1 secretion into the extracellular fluid, including cerebrospinal fluid and blood, is related to Parkinson’s disease (PD) and cancer pathogenesis. Here, we review the current knowledge regarding DJ-1’s roles as a ubiquitous cytoprotective protein controlling numerous signaling pathways, secretion, and therapeutic potentials.
Association of 25(OH)D Serum Level with Degree of WOMAC Index in Elderly Female Patients with Knee Osteoarthritis at KPKM FK UIN Jakarta
Authors: Wahyudi Ananda Hadist , Zaki Achmad , Widjajakusumah M. Djauhari , Lutfie Syarief Hasan , Muniroh Muniroh 
Published: July 2022

Background. Osteoarthritis (OA) is a chronic, progressive, degenerative disease which incidence increase with age dan occured majority in female. Pain in OA occurs due to accumulative process of degradation, repairment, and inflammation that causes symptoms of pain accompany with decrease in joint activity and function. These symptoms in elderly people, count about 9,8% of Indonesian population in 2020 which is muslim in majority, often causing complaints of difficulties to perform certain movements in shalat. Vitamin D is a nutritional factor which is known from several research wouldinhibit progressive joint destruction and relief of painful symptoms. And may have an important role to prevent the progressive process of the disease, thus promising to help the elderly to perform the shalat without knee joint problems. Objectives. The research’s objective was to determine the association between 25(OH)D serum level and the degree of WOMAC index of pain, stiffness, and functionality of knee OA in elderly female patients at Public Health Clinics (KPKM) Faculty of Medicine, Syarif Hidayatulloh State Islamic University of Jakarta (FK UIN Jakarta). Methods. The research used analytic Cross-Sectional design, with 106 elderly female as respondents, whose pain degree, stiffness, and functionality were measured using the WOMAC questionnaire of Knee OA and 25(OH)D serum level wasexamine. Results. Chi Square Fisher statistical analysis showed that there is no significant statistical association found (p 0,689) between 25(OH)D serum level and the degree of WOMAC index of knee OA in elderly female patients at KPKM FK UIN Jakarta. Conclusion. There is no significant statistical association found between serum vitamin D level and degree of WOMAC index of knee OA in elderly female patients at KPKM FK UIN Jakarta
Effect of 12 Weeks Vitamin D Supplementation (Alphacalcidol) on Blood Pressure in Elderly Women Patients
Authors: Zaki Achmad , Nabila Nida , Widjajakusumah M. Djauhari , Ardini Witri , Nitalia Mery 
Published: July 2022

Background : Cardiovascular disease have overtaken communicable disease for being the main killer worldwide. Hypertension or high blood pressure is one of the risk factors. Elderly women statistically have a high prevalence of hypertension. Vitamin D is known to affect blood pressure and many studies showed the association between vitamin D and blood pressure with varying result. This study aim to evaluate the effect of vitamin D supplementation (alphacalcidol) for 12 weeks and change in blood pressure of elderly women patients in community health service clinic (KPKM) Medical Faculty Syarif Hidayatullah State Islamic University of Jakarta (FK UIN Jakarta), with pre and hypertension grade 1 patients in majority. Methods : Analytical pre-post study design was conducted as a part of an RCT (Randomized Controlled Trial) studies with 106 participants of elderly women (45 intervention group, 61 control group).Results : Vitamin D deficiency in the intervention group significantly decreased post-supplementation from 22.2% to 8.9%. Subgroup analysis showed the decrease in blood pressure is greater in the subgroup middle-age elderly than young-age elderly category. Even though there was a significant change in the diastolic blood pressure in the subgroup of middle-age elderly post supplementation (p=0.03), Mann-Whitney statistical analysis showed that 12 weeks vitamin D supplementation (alphacalcidol) did not significantly effect the pre and post systolic nor diastolic blood pressure (p>0,05). Conclusion : The study did not found significant effect of 12 weeks Vitamin D (alphacalcidol) supplementation on blood pressure in elderly women patients.
High Risk Primary Percutaneous Coronary Intervention (Pci) in Patient with Acute Stemi Anterior, Chronic Kidney Disease, and Confirmed Covid-19
Authors: Moeswir Dede , Muhammad Fadhil , Nurbaeti Putri 
Published: July 2022

Background: An acute ST-elevation myocardial infarction (STEMI) anterior occurs due to occlusion of left anterior descending artery (LAD) branch of left coronary artery. The occlusion causing transmural myocardial ischemia which in turn to myocardial infarction due to myocardial injury or necrosis. Not only Primary Percutaneous Coronary Intervention (PCI) should be performed in STEMI less than 120 minutes as the risk of the adverse events would increase if exceeding the total ischemic time, but also the procedure can be high risk in patients with multiple clinical factors or comorbidities which can increase the risk of complications.Case Report: We report a case of a 57 years old man who presented Acute STEMI Anterior, Coronary Artery Disease (CAD) 3 Vessel Diseases (VD), Hypertension Heart Disease (HHD), Chronic Kidney Disease (CKD) on Hemodialysis (HD), with COVID-19 confirmed.Results: The left coronary artery was successfully stented by PCI and Coronary Angiogram (CAG) procedures with TIMI 3 flow, minimal bleeding and others complications.
Evaluación de la validez de factores de corrección para estimar la incertidumbre estándar de una distribución triangular con un intervalo de cobertura del 95 %
Authors: Molina-Castro Gabriel 
Published: July 2022

Recientemente, la estimación de incertidumbre de medida se convirtió en un tópico de gran interés para el reporte de inventarios de gases de efecto invernadero (GEI) en Costa Rica. En este contexto, una guía metodológica nacional del Programa País de Carbono Neutralidad (PPCN) ha surgido como base para el desarrollo local de esta temática, pero unos pocos aspectos de su contenido carecen de una explicación clara que justifiquen su implementación. El presente estudio evalúa la validez del uso de factores de corrección, propuestos por esta guía, que amplían la incertidumbre estándar estimada mediante el ajuste una distribución triangular, en presencia de un intervalo de cobertura del 95 %. Para ello, se simularon 3124 escenarios de distribuciones triangulares y se les estimó una incertidumbre estándar considerando que los límites simulados delimitan un intervalo de cobertura al 100 % (u100) y otra considerando un intervalo de cobertura al 95 % (u95), evaluando dos posibles interpretaciones sobre la ubicación del intervalo para esta última. Los factores de corrección FC se estimaron para cuatro diferentes grupos de escenarios como las pendientes entre u95 y u100, estimadas a partir de una regresión por mínimos cuadrados utilizando el software estadístico R. Se obtuvieron resultados entre 1,23 y 1,29, con un valor global de 1,25. Estos valores son consistentes con los encontrados en la guía metodológica nacional, comprobando así su validez y aplicabilidad. Finalmente, se sugiere el uso del factor de corrección de 1,25 como aproximación práctica para todos los escenarios evaluados, lo que podría facilitar su implementación homologada por los usuarios.
Metodología para la gestión de recursos de consumo energético durante el proceso constructivo
Authors: Solís Acuña Mariana , Mata Abdelnour Erick 
Published: July 2022

En Costa Rica existe un vacío en la creación de políticas para la gestión eficiente del consumo de recursos y del desarrollo de estadísticas de consumo de energía, que permita medir el desempeño de la sostenibilidad en la construcción. Por lo tanto, se realizó una investigación con el propósito de reconocer el estado de desarrollo de control y la gestión eficiente de recursos de consumo energético en la construcción a nivel internacional y nacional.
Posteriormente, se desarrollaron procesos y herramientas para la creación de una metodología, con el fin de generar una primera aproximación para estimar y registrar el consumo energético de edificaciones verticales en construcción y definir estadísticas en desempeño. Esta se aplicó en dos proyectos de edificios verticales durante la construcción de obra gris, con el fin de analizar la gestión del consumo de recursos. Además, esta metodología propuesta obtuvo un alto grado de aceptación por parte de un comité de validación, la cual fue considerada válida para la estimación y registro de estadísticas de sostenibilidad a lo largo del desempeño en el proyecto, lo cual ayuda a tener un control de los consumos de recursos.
Pediatricians’ Competence in Prevention, Risk Determination or Detection of Suicidal Behavior in Children: Cross-Sectional Survey Study
Authors: Basova Anna Y. , Bebchuk Marina A. , Ustinova Natalia V. , Namazova-Baranova Leyla S. , Efendiyeva Kamilla E. , Vishneva Elena A. 
Published: July 2022

Background. Child and adolescent suicides remain one of the most painful public issues. The COVID-19 pandemic has aggravated this topic as the number of suicides among children population has increased in this period. Research and practice guidelines identify the leading role of primary care physicians in the prevention, identification, and routing of patients with suicidal behavior. At the same time, there were no studies on pediatricians’ competence in the field of suicides.Objective. The aim of the study is to study pediatricians’ competence in prevention, risk determination or and detection of suicidal behavior.Methods. Cross-sectional study was conducted with the usage of original electronic questionnaire aimed on identifying the level of pediatricians’ competence in evaluating suicidal behavior in children. Questionnaire included 18 questions.Results. We have received 208 electronic questionnaires. 97.1% of specialists have confirmed that they evaluate emotional status of their patients during admission. During admission: 86.1% of specialists have considered the characteristics of children appearance, facial expression, voice intonation, 65.4% — have asked questions about mood, 62.5% — have interviewed parents. 98.6% of specialists pay attention to the presence of self-inflicted injuries marks, 88.4% — ask about the origin of these injuries. Only 36.1% of respondents ask patients about suicidal thoughts, intentions, or actions. Only 69.3% of specialists are ready to refer their patients to psychologist, and 51.7% — to psychiatrist.Conclusion. Even though most surveyed pediatricians notice signs of suicidal intent (low mood, self-inflicted injuries), they avoid discussing the topic of suicide during admission. Increasing the competence of pediatricians should be aimed on destigmatisation in the field of mental health, increasing the knowledge level, and developing practical skills in working with children with suicidal behavior.
La construcción del paisaje cultural de Araponga-MG
Authors: Miranda Vanessa Lopes de , Civale Leonardo 
Published: July 2022

Este trabajo forma parte de los resultados de una investigación que tiene como objetivo comprender las influencias del turismo después de la implementación del Parque Estatal Serra do Brigadeiro (PESB) en el paisaje de Araponga - MG., utilizado como marco de tiempo desde 1996 hasta 2020. Discute el papel del paisaje en la discusión sobre el patrimonio cultural en una pequeña ciudad de Minas Gerais, considerando que recibe influencia del turismo proveniente del PESB. Al acercarnos al "paisaje" consideramos aspectos morfológicos y simbólicos de este término polisémico, se toma que está ligado a la forma en que las personas experimentan y se manifiestan en el espacio, por lo tanto, se trata del interés de comprender la percepción de la comunidad que utiliza el paisaje, ya sea como vivienda, trabajo o fuente de alimento. El Parque Estatal Serra do Brigadeiro fue inaugurado en medio de conflictos, tales conflictos permitieron el reconocimiento de una comunidad unida dispuesta a luchar por el uso de su espacio, siendo Araponga uno de los protagonistas en este contexto. Hubo, más tarde, la búsqueda del equilibrio entre la mirada externa, del especialista en patrimonio cultural o ambiental, y la mirada de la comunidad local que percibía y utilizaba ese espacio. El estudio del paisaje exige comprender aportes que vayan más allá de lo visto, por lo tanto, es necesario profundizar en las relaciones sociales presentes en la memoria e historia de un grupo determinado para comprender los cambios que ocurrieron y sus significados, así como conciliar perspectivas externas e internas al municipio.
Lester Kruger Born, Ernst Maximilian Posner, and the American Influence on the Reshaping of German Archives after the Second World War
Authors: Haas Philip , Schürrer Martin 
Published: July 2022

ABSTRACT
At the end of the Second World War, the collapse of the Prussian archival system lead to a gap in archival administration. Education and training of archivsts who broke ties with Nazi-era principles, and who adopted ties to American archival theory and practice, became a priority. This article first examines the contribution of American archival protection officers to this endeavor, including the establishment of an archival school in the American Zone, and the influence of Ernst Posner's archival theory. This article examines the historical context of these events and concludes by asking the question of what traces the American commitment has left behind in the archival system of Germany.
a National Characteristic Program For Growing Student’s Nasionalism Character At Immersion Primary School Ponorogo
Authors: Azizah Wafiqul 
Published: July 2022

Abstract
Education is an effort to form individuals to grow into responsible, moral, creative, independent, and noble individuals. In forming individuals with noble character, character education is needed to prepare individuals who have character and are ready to face the challenges of the times. The implementation of character education is in line with the character crisis caused by the increasing development of globalization. The impact of the development of globalization has brought students to like some trends in social media that are not in accordance with the development of students' ages. In minimizing the impact of the development of globalization, Immersion Primary School Ponorogo developed a national habituation program to cultivate the character of nationalism as the basis for students' identity to love and respect the nation's culture. The purpose of this study is to describe: (1) the form of inculcating the character of nationalism through a national habituation program; (2) the implication of the national habituation program on the development of the character of nationalism; and (3) the effectiveness of the implementation of the national habituation program in instilling the character of nationalism. This research was designed using a qualitative approach with the type of case study. As a result, at Immersion Primary School Ponorogo: (1) focusing on national habituation on aspects of the character of discipline and love for the homeland with three forms of habituation, namely giving examples, spontaneous activities, and routine activities. Meanwhile, in fostering the character of habituation nationalism, in the form of routine activities and programmed activities; (2) national habituation activities have implications for the growth of students' awareness and responsibility to carry out national habituation without any encouragement from the teacher and the growth of students' self-confidence to take part in various competitions; (3) the implementation of the habituation program has been as expected and there is a match between the implementation of the habituation program and the initial goal.

Keywords: habituation program, national habituation, nationalism character
The Application of The Team Assisted Individualization Cooperative Learning Model in Improving Learning Outcomes of Class VII Students of Junior High School State 1 Pringapus for The 2021/2022 Academic Year on Data Presentation Materials
Authors: Rofilia Maulina , Titikusumawati Eni 
Published: July 2022

This research aims to determine the improvement of student learning outcomes in class VII C of Junior High School State 1 Pringapus by using the TAI type cooperative learning model in the data presentation material. The problem behind this research is the low learning outcomes of class VII C students during PTS (Middle Semester Assessment) 1 and it made the class with the lowest average math score.
This research is a classroom action research with research stages, namely planning, implementation, observation and reflection. Research data obtained through written tests, student worksheets, observation, questionnaires, field notes and documentation.
The results of descriptive research analysis showed an increase in student learning outcomes for class VII C Junior High School State 1 Pringapus through the TAI type cooperative learning model on data presentation material. Improved learning outcomes can be known through the evaluation results in each cycle. In the first cycle, the mastery of students was 52,94% or 18 students who completed with an average learning outcome of 79,85 and in the second cycle the number of learning mastery increased to 82,35% or 28 students with an average learning outcome of 87,79. Meanwhile, the results of the student response questionnaire also showed 74,74% results, which means that students agree or like to use the TAI type cooperative learning model in teaching and learning activities at school.