bluuebunny/crossref_metadata_2025_split huggingface dataset:
Authors: Rahmaniyah Siti , Fau Yohanes Deo , Pradita Angria , Fariz Achmad 
Published: May 2022

ABSTRACT
INTRODUCTION: Osteoarthritis is a symptom that often comes in elderly people with chronic progressive conditions that can cause movement disorders and can interfere with daily activities. Isometric exercise is one of the non-operative treatment methods in reducing pain and improving the functional ability of Osteoarthritis patients. This exercise is very helpful for reducing joint torment and can further develop work in patients with intense agony and ongoing torment Osteoarthritis. This review intends to decide the impact of isometric exercise on changes in knee torment in essential osteoarthritis Method: This sort of exploration is a semi trial utilizing One Group Pretest and Posttest plan. Complete populace of 30 individuals with a conclusion of osteoarthritis who met the consideration and prohibition measures. Irregular inspecting with tests in this review, to be specific all patients with essential osteoarthritis matured 50 years and over, adding up to 15 individuals with male and female sexual orientation Result: Isometric exercise was allowed double seven days for quite a long time and knee torment was estimated utilizing a VAS (Visual Analog Scale) estimating instrument. With the Wilcoxon test, the middle worth of pre 6.53 and post was 4.40 with a distinction of 2.13. So the P esteem is 0.000<0.05. So the outcomes acquired in this review demonstrate that there is an impact of giving isometric exercise on reducing knee pain in primary osteoarthritis in the Physiotherapy poly at RSUD dr. H. Moh. Anwar Sumenep. Discussion: the outcomes acquired in this review demonstrate that there is an impact of giving isometric exercise on reducing knee pain in primary osteoarthritis. So primary osteoarthritis patients can do isometric exercise independently so very helpful for reducing joint torment in patients.

Keywords: Isometric exercise, knee pain, osteoarthritis primer
IMPLEMENTATION OF THE KIRKPATRICK EVALUATION MODEL IN BALAI DIKLAT KEAGAMAAN BANJARMASIN
Authors: Amalia Jadwa 
Published: May 2022

Abstract: Nowadays government agencies are required to improve the quality of their services to the community. One of the steps taken to improve that is through training activities. In order to achieve the expected goals, the training that is held must go well, from planning to evaluation of results. Therefore, the evaluation must be done seriously and use the right method or model. The training evaluation model that has been applied at the BDK Banjarmasin refers to the four-level evaluation model or what is often called the Kirkpatrick evaluation model. However, based on initial observation, most of the employees and even some trainers do not know about the Kirkpatrick's evaluation model itself. This can be seen from the number of employees and coaches who do not understand how to do the evaluation, or how to analyze the results. Observations made show that the application of Kirkpatrick's evaluation model in the training at the BDK Banjarmasin was still not effective, because most only focus on levels 1, 2 and 3 while level 4 are still rarely done. Keywords: evaluation; Kirkpatrick; education; training.
Abstrak: Saat ini instansi pemerintah dituntut untuk meningkatkan kualitas pelayanannya kepada masyarakat. Salah satu langkah perbaikan yang dilakukan yaitu melalui kegiatan pelatihan. Untuk mencapai tujuan yang diharapkan, pelatihan yang diadakan harus berjalan dengan baik, mulai dari perencanaan hingga evaluasi hasil. Oleh karena itu, evaluasi harus dilakukan secara serius dan menggunakan metode atau model yang tepat. Model evaluasi pelatihan yang telah diterapkan di BDK Banjarmasin mengacu pada model evaluasi empat tingkat atau yang sering disebut dengan model evaluasi Kirkpatrick. Namun berdasarkan pengamatan awal, sebagian besar karyawan bahkan beberapa trainer belum mengetahui tentang model evaluasi Kirkpatrick itu sendiri. Hal ini terlihat dari masih banyaknya pegawai dan pembina yang belum memahami cara melakukan evaluasi, atau cara menganalisis hasil. Pengamatan yang dilakukan menunjukkan bahwa penerapan model evaluasi Kirkpatrick dalam pelatihan di BDK Banjarmasin masih belum efektif, karena sebagian besar hanya fokus pada level 1, 2 dan 3 sedangkan level 4 masih jarang dilakukan.

Kata kunci: evaluasi; Kirkpatrick; pendidikan; pelatihan.
The Effects of Intrinsic and Extrinsic Rewards on Employees' Performance
Authors: Alimawi Mohammed , Muda @ Ismail Farah laili 
Published: May 2022

The requirements for success and the achievement of the planned goals, force companies and institutions to optimize the utilization of the employees, especially those who have acquired experience in their field of work within a specific work environment. In order to make sure the employees are continuously in high momentum and performance, the employees must be given sufficient rewards. This conceptual paper discusses on the employees performace and how it is influenced by rewards. In an occupational sector, rewards can be classified into two categories, which are intrinsic rewards and extrinsic rewards. Various literatures were studied and analyzed. The study found that most of employees performance, either positive or negative were influenced by the rewards they received.

Keperluan untuk meraih kejayaan dan mencapai matlamat yang dirancang, memaksa syarikat dan institusi untuk mengoptimumkan penggunaan pekerja, terutamanya mereka yang telah memperoleh pengalaman dalam bidang kerja mereka dalam persekitaran kerja tertentu. Bagi memastikan pekerja sentiasa berada dalam momentum dan prestasi yang tinggi, pekerja mesti diberi ganjaran yang mencukupi. Kertas konsep ini membincangkan tentang prestasi pekerja dan bagaimana ia dipengaruhi oleh ganjaran. Dalam sektor pekerjaan, ganjaran boleh dikelaskan kepada dua kategori, iaitu ganjaran intrinsik dan ganjaran ekstrinsik. Pelbagai literatur telah dikaji dan dianalisis. Kajian mendapati kebanyakan prestasi pekerja, sama ada positif atau negatif dipengaruhi oleh ganjaran yang mereka terima.
Current Issues on Assessment in Education during Pandemic
Authors: Wok Zaki Azurawati , Darmi Ramiaida , Selamat Suzanah 
Published: May 2022

School Based Assessment (SBA) is a concept integrated in the Malaysian education system to harmonise assessment of an educator into the process of teaching and learning, with an idea to optimize students’ understanding of a subject they are learning. When the Covid-19 virus ravages the world, the education sector was not spared, schools were quick to be shut down in fear of the disease. It was not long before the education system was forced to adapt the unconventional method of leaning to outlast the pandemic. Rushing, even in good intention, comes with myriad of the issues and the concern of the effectivity of SBA in this new environment is not excused. With student focused education principles rooted in the education system, to being virtually available in a virtual classroom is a challenge to both to the teachers and students. To enforce discipline and to engage individual student in of itself is not an easy task let alone when both parties separated by miles away. Thus, this paper will cast an overview the effects of the Covid-19 Pandemic to the Malaysian education system, issues related to online assessment in the Malaysia education system during pandemic and assessment practices, challenges and solution during pandemic by other countries.

Pentaksiran Berasaskan Sekolah (PBS) adalah konsep penilaian yang digunapakai oleh guru-guru dalam pengajaran dan pembelajaran bagi mengoptimumkan pemahaman pelajar terhadap sesuatu subjek yang mereka pelajari. Disiplin yang melibatkan pelajar dalam pembelajaran bukanlah tugas yang mudah, apatah lagi ketika kedua-dua pihak dipisahkan dengan jarak. Oleh itu, artikel ini akan menjelaskan kesan Pandemik COVID-19 terhadap sistem pendidikan Malaysia, isu-isu yang berkaitan dengan penilaian dalam talian dalam sistem pendidikan Malaysia semasa pandemik dan amalan penilaian, cabaran dan penyelesaian semasa pandemik yang dilaksanakan oleh negara lain. Metodologi yang digunakan dalam artikel ini adalah kualitatif, melalui tinjauan dokumen secara khusus mengenai kajian masa terdahulu dari tahun 2019 hingga 2021. Kajian terdahulu menunjukkan bahawa semasa pandemik e-Pembelajaran banyak dipraktikan, dan PBS menggantikan peperiksaan formal. Selain itu, keperluan untuk alat teknologi dan sambungan internet menjadi isu yang tidak pernah berakhir dalam kalangan pelajar. Walau bagaimanapun, beberapa negara telah mempraktikkan penilaian dalam talian untuk menggantikan amalan penilaian formal di dalam kelas. Kesimpulannya, sebarang perubahan dalam sistem pendidikan, memerlukan tindakan segera dari setiap pihak yang terlibat, termasuk guru, pelajar dan ibu bapa. Tidak ada seorang pun kanak-kanak yang ketinggalan atau ‘No child left behind’ adalah dasar yang harus menjadi asas keutamaan sistem pendidikan semasa wabak ini.
Penelitian Awal Terhadap Penglibatan Orang Arab dalam Kerja Amal di Malaysia Sebelum dan Selepas Perang Dunia Kedua
Authors: Abdul Latiff Latifah 
Published: May 2022

Dahulu, orang Arab pada umumnya lebih dikenali sebagai ulama atau golongan agamawan dalam kalangan masyarakat Melayu di Malaysia. Orang Arab khasnya daripada keturunan Sayyid dari Hadhramaut, Yaman tidak hanya terlibat dalam aktiviti dakwah, tetapi mereka juga turut melibatkan diri dalam perniagaan dan keusahawanan. Oleh kerana kebanyakan daripada mereka lebih dikenali masyarakat sebagai pendakwah atau dai dan ulama, maka, makalah ini cuba mengetengahkan penglibatan beberapa orang tokoh Arab keturunan Sayyid dalam aspek kebajikan dan kerja amal mereka di Malaysia sebelum Perang Dunia Kedua. Kajian ini menggunakan kaedah penyelidikan berbentuk kualitatif, mengkaji dan menganalisis penglibatan orang Arab dalam kerja amal dengan mengakses bahan daripada rekod arkib seperti surat dan dokumen serta penulisan ilmiah. Kajian mendapati keluarga Arab seperti al-Kaff, al-Sagoff, al-Junied dan al-Attas merupakan antara keluarga Arab yang berjaya di Malaysia dalam pelbagai bidang perniagaan. Walaupun mereka berjaya dalam bidang perniagaan, namun mereka juga turut menyumbang kepada masyarakat melalui aktiviti dan kerja amal seperti mewakafkan tanah perkuburan, membina masjid dan mendirikan madrasah yang dibiayai oleh dana wakaf.

The Arabs popularly known as orang Arab among Malays were once known as religious men in the society. The Arabs especially the Hadhrami Sayyids who originated from Hadhramaut, Yemen were not only involved in dakwah activities but also engaged in business and entrepreneurship. Since many of them were only known by the society as preachers (dai) and religious scholars (ulama), therefore, this paper attempts to highlight the humanitarian aspect of the Arabs in particular the prominent Arabs in fulfilling their social responsibilities in Malaya before the World War Two. This article employed a qualitative research method studying and analyzing the Arabs’ engagement in charity works by accessing records from archives such as letters, records, and documents as well as literature from scholarly works. It is found that the Arab families such as al-Kaff, al-Sagoff, al-Junied and al-Attas were among those Arab families who succeeded in Malaya. They were not only concerned about their business ventures, but also involved in philanthropic works such as endowing funeral grounds, building mosques, and establishing madrasah that are mostly funded through endowment funds.
Kertas Konsep Pengintegrasian Ayat Hafazan al-Quran dengan Ilmu Aqli: Ke Arah Pembangunan Model di Kolej GENIUS Insan
Authors: Ahmad Hilmi Ahmad Bazli , Saleh Muhammad Hafiz , Sulaiman @ Mohamad Adibah 
Published: May 2022

Pendidikan tahfiz di Malaysia semakin berkembang dengan pengenalan Kurikulum Bersepadu Tahfiz (KBT). Mutakhir ini terdapat usaha untuk mengintegrasikan hafazan al-Qur’an dengan subjek-subjek akademik yang dipelajari pelajar. Namun, model integrasi ayat hafazan dengan ilmu aqli berlandaskan disiplin ilmu tafsir bagi kegunaan pelajar peringkat menengah belum diketengahkan. Kertas konsep ini bertujuan membangunkan model pengintegrasian ayat hafazan Al-Quran dengan ilmu aqli di Kolej GENIUS Insan. Kajian ini menggunakan pendekatan Design and Developmental Research (DDR) yang diasaskan oleh Richey dan Klein (2007) yang mempunyai tiga fasa iaitu analisis keperluan, reka bentuk dan pembangunan, dan penilaian kebolehgunaan. Bagi analisis keperluan, tinjauan menggunakan temu bual dilakukan dalam kalangan guru, alumni, dan pelajar Kolej GENIUS Insan untuk melihat bagaimana pengintegrasian ayat hafazan Al-Quran dengan ilmu aqli diimplementasikan. Fasa kedua ialah mereka bentuk model menggunakan kaedah Focus Group Discussion (FGD) melibatkan 7 orang pakar dan membangunkan model menggunakan pendekatan Fuzzy Delphi Method melibatkan 12 pakar. Model prototaip untuk integrasi ayat hafazan Al-Quran dengan ilmu aqli akan menjadi hasil fasa ini. Pada fasa ketiga, Nominal Group Technique (NGT) melibatkan 9 panel pakar akan digunakan untuk menilai kebolehgunaan model.

Tahfiz education in Malaysia is growing with the introduction of the Tahfiz Integrated Curriculum (KBT). Recently, there have been efforts to integrate Quranic memorisation with academic subjects. However, the model of integrating Quranic memorised verses with aqli knowledge based on the discipline of tafsir for the use of secondary level students has not been highlighted. Therefore, this concept paper presents research proposals to develop a model of integrating the Quranic memorised verse with the aqli knowledge in the Kolej GENIUS Insan using Design and Development Research (DDR) approach. Through this conceptual paper, the theory of the Quran as a source of knowledge, constructivism theory, Adnan integration of naqli and aqli knowledge model, and Pedaste inquiry-based learning model will be the basis theory and model in the development of the model.
Cardiovascular Magnetic Resonance in Early Detection of Radiation Associated Cardiotoxicity With Chest Radiation
Authors: Vallabhaneni Srilakshmi , Wang Yue , Zhang Ying , Smith Amanda , Zou Wei , Feigenberg Steven , Plastaras John , Freedman Gary , Witschey Walter R. T. , Ky Bonnie , Han Yuchi 
Published: May 2022

BackgroundChest radiation therapy (RT) is known to be associated with cardiotoxicity. However, the changes in myocardial tissue characterization with radiation-induced cardiotoxicity are not well-understood.ObjectivesThis study sought to assess the changes in left ventricular function and tissue characterization using cardiovascular magnetic resonance (CMR) in patients receiving RT.Materials and MethodsBetween June 2015 and July 2018, we enrolled patients with breast, lung cancer, or lymphoma with plan to receive chest radiation after chemotherapy. CMR was performed using a 1.5T scanner at baseline and 6 months after RT. Myocardial volume, function, strain analysis using feature tracking, and tissue characterization including late gadolinium enhancement (LGE), T1, T2, T1ρ (rho), and extracellular volume fraction (ECV) were measured and compared using non-parametric methods.ResultsThe final cohort consisted of 16 patients, 11 of whom completed both baseline and follow-up CMRs. Patients were matched to 10 healthy controls. At baseline prior to RT, compared to controls, patients had lower global circumferential strain (GCS) (15.3 ± 2.2% vs.18.4 ± 2.1%, p = 0.004), and elevated T2 (47.9 ± 4.8 ms vs. 45.0 ± 1.5 ms, p = 0.04) and T1ρ values (78.4 ± 5.9 vs. 66.9 ± 4.6 ms, p &lt; 0.001). Two patients had LGE. There was no significant difference in the average T1 values or ECV. There was a trend toward lower LV ejection fraction and global longitudinal strain (GLS). At 6-month follow-up after RT, there were no significant changes in all the CMR parameters.ConclusionAt 6-month following chest radiation therapy, there was no change in LV and RV EF, LV and RV GLS, LV GCS, and myocardial tissue characterization using LGE, T1, ECV, T2, and T1ρ in a small cohort of patients. However, the baseline T2 and T1ρ were elevated and LV GCS was reduced compared to controls indicating ongoing myocardial edema and subclinical dysfunction post-chemotherapy.
MG53 Inhibits Necroptosis Through Ubiquitination-Dependent RIPK1 Degradation for Cardiac Protection Following Ischemia/Reperfusion Injury
Authors: Wang Qiang , Park Ki Ho , Geng Bingchuan , Chen Peng , Yang Chunlin , Jiang Qiwei , Yi Frank , Tan Tao , Zhou Xinyu , Bian Zehua , Ma Jianjie , Zhu Hua 
Published: May 2022

RationaleWhile reactive oxygen species (ROS) has been recognized as one of the main causes of cardiac injury following myocardial infarction, the clinical application of antioxidants has shown limited effects on protecting hearts against ischemia–reperfusion (I/R) injury. Thus, the precise role of ROS following cardiac injury remains to be fully elucidated.ObjectiveWe investigated the role of mitsugumin 53 (MG53) in regulating necroptosis following I/R injury to the hearts and the involvement of ROS in MG53-mediated cardioprotection.Methods and ResultsAntioxidants were used to test the role of ROS in MG53-mediated cardioprotection in the mouse model of I/R injury and induced human pluripotent stem cells (hiPSCs)-derived cardiomyocytes subjected to hypoxia or re-oxygenation (H/R) injury. Western blotting and co-immunoprecipitation were used to identify potential cell death pathways that MG53 was involved in. CRISPR/Cas 9-mediated genome editing and mutagenesis assays were performed to further identify specific interaction amino acids between MG53 and its ubiquitin E3 ligase substrate. We found that MG53 could protect myocardial injury via inhibiting the necroptosis pathway. Upon injury, the generation of ROS in the infarct zone of the hearts promoted interaction between MG53 and receptor-interacting protein kinase 1 (RIPK1). As an E3 ubiquitin ligase, MG53 added multiple ubiquitin chains to RIPK1 at the sites of K316, K604, and K627 for proteasome-mediated RIPK1 degradation and inhibited necroptosis. The application of N-acetyl cysteine (NAC) disrupted the interaction between MG53 and RIPK1 and abolished MG53-mediated cardioprotective effects.ConclusionsTaken together, this study provided a molecular mechanism of a potential beneficial role of ROS following acute myocardial infarction. Thus, fine-tuning ROS levels might be critical for cardioprotection.
Additive Impact of Interleukin 6 and Neuron Specific Enolase for Prognosis in Patients With Out-of-Hospital Cardiac Arrest – Experience From the HAnnover COoling REgistry
Authors: Akin Muharrem , Sieweke Jan-Thorben , Garcheva Vera , Martinez Carolina Sanchez , Adel John , Plank Pia , Zandian Paris , Sühs Kurt-Wolfram , Bauersachs Johann , Schäfer Andreas 
Published: May 2022

BackgroundPatients after out-of-hospital cardiac arrest (OHCA) are at increased risk for mortality and poor neurological outcome. We assessed the additive impact of interleukin 6 (IL-6) at admission to neuron-specific enolase (NSE) at day 3 for prognosis of 30-day mortality and long-term neurological outcome in OHCA patients.MethodsA total of 217 patients from the HAnnover COoling REgistry with return of spontaneous circulation (ROSC) after OHCA and IL-6 measurement immediately after admission during 2017–2020 were included to investigate the prognostic value and importance of IL-6 in addition to NSE obtained on day 3. Poor neurological outcome was defined by cerebral performance category (CPC) ≥ 3 after 6 months.ResultsPatients with poor outcome showed higher IL-6 values (30-day mortality: 2,224 ± 524 ng/l vs 186 ± 15 ng/l, p &lt; 0.001; CPC ≥ 3 at 6 months: 1,440 ± 331 ng/l vs 180 ± 24 ng/l, p &lt; 0.001). IL-6 was an independent predictor of mortality (HR = 1.013/ng/l; 95% CI 1.007–1.019; p &lt; 0.001) and poor neurological outcome (HR = 1.004/ng/l; 95% CI 1.001–1.007; p = 0.036). In ROC-analysis, AUC for IL-6 was 0.98 (95% CI 0.96–0.99) for mortality, but only 0.76 (95% CI 0.68–0.84) for poor neurological outcome. The determined cut-off value for IL-6 was 431 ng/l for mortality (NPV 89.2%). In patients with IL-6 &gt; 431 ng/l, the combination with NSE &lt; 46 μg/l optimally identified those individuals with potential for good neurological outcome (CPC ≤ 2).ConclusionElevated IL-6 levels at admission after ROSC were closely associated with 30-day mortality. The combination of IL-6 and NSE provided clinically important additive information for predict poor neurological outcome at 6 months.
Fenestrated and Branched Stent-Grafts for the Treatment of Thoracoabdominal Aortic Aneurysms: A Systematic Review and Meta-Analysis
Authors: Hu Zhongzhou , Zhang Zheng , Liu Hui , Chen Zhong 
Published: May 2022

PurposeTo investigate the safety and efficacy of total endovascular repair for thoracoabdominal aortic aneurysms (TAAAs) with fenestrated and branched stent-grafts.MethodsThe MEDLINE, EMBASE, and Cochrane databases were searched between January 2001 and December 2021 to identify literature relevant to the use of fenestrated and branched endografts for the treatment of TAAAs. Studies with &lt;4 cases and those on juxtarenal or pararenal aortic aneurysms were excluded. Meta-analyses were conducted to evaluate spinal cord ischemia (SCI), irreversible SCI, renal insufficiency, dialysis, endoleak, reintervention, target vessel patency, 30-day mortality and overall mortality. Fourteen studies comprising 1,114 patients (mean age 72.42 years, 847 men) were selected. The mean TAAA diameter was 67 mm. The Crawford TAAA classification was type I-III in 759 cases, type IV in 344 cases, and type V in 10 cases. Outcomes of the meta-analysis are reported as proportions and 95% confidence intervals (CIs).ResultsThe pooled rates for 30-day mortality and overall mortality were 6% and 18%, respectively. The pooled rate for technical success was 94% (95% CI, 93–96%), for SCI was 8% (95% CI, 7–10%), for irreversible SCI was 6% (95% CI, 4–7%), for reversible SCI was 5% (95% CI, 4–6%), for reversible SCI was 2% (95% CI, 2–3%), for renal insufficiency was 7% (95% CI, 5–10%), for dialysis was 3% (95% CI, 2–4%), for target vessel patency was 98% (95% CI, 97–99%), and for reintervention was 15% (95% CI, 9–24%).ConclusionFenestrated and branched endografts for the treatment of TAAAs are safe and effective with acceptable early results. Lifelong regular follow-up and additional prospective studies are necessary to substantiate whether this technique is valid.