bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Pernikahan Usia Muda terhadap Gugatan Cerai di Pengadilan Agama Antapani Bandung
Authors: Badruzaman Dudi 
Published: May 2022

AbstractMarriage is a physical and spiritual bond between a man and a woman as husband and wife with the aim of forming a happy and eternal family. Marriage life which is a goal that is desired by Islam. However, in reality, to realize these ideal goals, some couples experience difficulties. If the problem cannot be resolved properly, it will lead to disputes and lead to divorce. The purpose of this study is to find out young marriage registered in the Antapani Religious Court in Bandung, to find out the level of divorce in the Bandung Antapani Religious Court, and to determine the effect of young marriage on the divorce rate in the Antapani Religious Court in Bandung. The population in this study used the Simple Random Sampling Technique with 30 couples filing for divorce. The method used in this research is descriptive research method with a quantitative approach. From the results of research that has been carried out that young marriage has a positive and significant effect on the divorce rate in the Antapani Religious Court in Bandung, which means that the younger the age of a person having a marriage, the higher the divorce rate. AbstrakPerkawinan adalah ikatan lahir dan batin antara seorang pria dengan seorang wanita sebagai suami istri dengan tujuan membentuk keluarga (rumah tangga) yang bahagia dan kekal. Kehidupan perkawinan merupakan satu tujuan yang sangat diinginkan oleh islam. Akan tetapi pada realitasnya untuk mewujudkan tujuan yang ideal tersebut sebagian pasangan suami istri mengalami kesulitan. Apabila permasalahan itu tidak dapat diselesaikan dengan baik, maka akan menimbulkan kepada perselisihan dan berujung pada perceraian. Tujuan dari penelitian ini yaitu untuk mengetahui pernikahan usia muda yang terdaftar di Pengadilan Agama Antapani Bandung, untuk mengetahui tingkat perceraian di Pengadilan Agama Antapani Bandung, dan untuk mengetahui pengaruh pernikahan usia muda terhadap tingkat perceraian di Pengadilan Agama Antapani Bandung. Populasi dalam penelitian ini menggunakan teknik simple random sampling dengan 30 pasangan yang ngajukan gugatan cerai. Metode yang digunakan dalam penelitian ini adalah metode penelitian deskriptif dengan pendekatan kuantitatif. Dari hasil penelitian yang telah dilakukan bahwa pernikahan usia muda berpengaruh terhadap tingkat perceraian di Pengadilan Agama Antapani Bandung, artinya bahwa semakin muda usia seseorang melakukan pernikahan maka semakin tinggi tingkat perceraian.
Chlorothalonil induces metabolic syndrome in mice by regulating host gut microbiota and bile acids metabolism via FXR pathways
Authors: Meng Zhiyuan , Yan Sen , Sun Wei , Yan Jin , Teng Miaomiao , Jia Ming , Tian Sinuo , Li Ruisheng , Huang Shiran , Diao Jinling , Chen Xiaojun , Zhou Zhiqiang , Qiu Jing , Zhu Wentao 
Published: May 2022

Abstract
Background: The most commonly used organochlorine pesticide nowadays, chlorothalonil (CHI), is ubiquitous in a natural environment and poses many adverse effects to organisms. Unfortunately, the toxicity mechanisms of CHI have not been clarified yet.Results: This study found that the CHI based on acceptable daily intake (ADI) level could induce metabolic syndrome (MetS) in mice, including obesity, hepatic steatosis, dyslipidemia, and insulin resistance. In addition, exposure to reglementary-dose CHI could induce an imbalance in the gut microbiota of mice, resulting in a significant increase in the ratio of Firmicutes to Bacteroidetes. Furthermore, the results of the antibiotic treatment and gut microbiota transplantation experiments showed that the reglementary-dose CHI could induce MetS in mice in a gut microbiota-dependent manner. Based on the results of targeted metabolomics and gene expression analysis, the reglementary-dose CHI could disturb the serum metabolism of bile acids (BAs) in mice, causing the inhibition of the signal response of BAs receptor farnesol X receptor (FXR) and leading to glycolipid metabolism disorders in liver tissue and epididymal white adipose tissue (epiWAT) of mice. The administration of FXR agonist GW4064 and CDCA could significantly improve the reglementary-dose CHI-induced MetS in mice.Conclusions: In conclusion, the reglementary-dose CHI was found to induce MetS in mice by regulating the gut microbiota and BAs metabolism via the FXR signaling pathway. This study provides evidence linking the gut microbiota and pesticides exposure with the progression of MetS, demonstrating the key role of gut microbiota in the toxic effects of pesticides.
Feasibility Verification and Electrical Performance of Additive-manufactured Flexible Microspiral Inductor Made of Copper Wire
Authors: Niu Wenjie , Yang Mengxue , Gong Yu , Liu Yu , Zhang Yanfang 
Published: May 2022

Abstract
In recent years, flexible electronic technology has been rapidly developed. Compared with common conductive materials, copper wire has the advantages of high conductivity and low cost. To verify the feasibility of fine copper wire as the conductive material in flexible microelectronic components, a microspiral inductor was taken as an example in this work. First, flexible passive microspiral inductors with 2.5, 4.5, and 6.5 turns were prepared by injection molding using the stereo lithography (SLA) technology to print a mold, with silicone rubber (Ecoflex) as the base material and copper wire as the conductive material. Second, theoretical models of the flexible microspiral inductors with different turns were numerically simulated, and physical experiments on the electrical performance of actual microspiral inductors were conducted under initial and deformation states. The two results were then compared and analyzed. The results showed that the maximum errors in the inductance, quality factor, and self-resonant frequency in the initial state were +18.17%, −19.33%, and 0.17 GHz, and those in the deformation state were +11.15%, −10.88%, and 0.09 GHz. The errors were no more than 20%. These results confirm the feasibility of using copper wire as the conductive material in flexible electronic components.
Repair of pectus excavatum in a patient with an Eloesser thoracostomy window: Sequential extrapleural Nuss procedure and modified Ravitch procedure
Authors: Han Jung Wook , Kim Jae Jun , Choi Won Kyu , Jeong Hye Yoon , Lee Young Eun 
Published: May 2022

Abstract
A 28-year-old man with a history of tuberculous empyema and pectus excavatum visited our hospital for progressive dyspnea and leg edema. The patient had undergone an Eloesser window operation for repetitive pleuro-cutaneous fistula due to chronic tuberculous empyema in the left thorax one year prior. Chest computed tomography demonstrated severe compression of the right ventricle and inferior vena cava and chronic empyema with the Eloesser window in the left thorax. Because conservative treatment had failed, the patient underwent a total extrapleural Nuss procedure, resulting in marked relief of compression and complete resolution of leg edema and congestive hepatopathy. However, he required ventilation support due to carbon dioxide retention. Therefore, the patient underwent a modified Ravitch procedure and was weaned off ventilation support. Herein, we represent the first report of a sequential extrapleural Nuss procedure and a modified Ravitch procedure in a patient with chronic tuberculous empyema with an Eloesser window.
Global French Spine Surgery Activity: Executive Report of Demographics Data and Trends
Authors: Chapon Renan , Meyblum Jean , Simon Laurie , Pelletier Yann , Broussolle Théo , Marty Hugo , Huneidi Maxime , MAINARD Nicolas 
Published: May 2022

Abstract
Background: To date, there is no demographic study of spinal surgery in France. We analyzed the French trend of spinal surgery as well as the variations in incidence according to the type of pathology, the type of institutions, and its distribution on the territory.Methods: Retrospective cohort study using French National Health Data, from 2016 to 2019. We analyzed the market sare, the leakage rate, the utilization rate and the attractiveness rate for each region. Results: There were 103,350 surgical acts on spinal degenerative pathologies in 2019, an increase of 5% since 2016. This increase is found in all procedures, particularly in traumatology with an increase of 34%, from 10,340 procedures in 2016 to 13,858 in 2019. There was a 75% increase in treatments for infectious diseases.There was a clear decrease in the total number of procedures between 2019 and 2020 corresponding to the global pandemic at COVID 19 with a total decrease of 13%.The majority of spinal surgery procedures are performed in private structures and represent almost two-thirds of total activity, i.e. 80,147 procedures in 2019 out of 126,183. The distribution of spinal surgery is based on the major population centers, the coastal areas, and the cities with university hospitals.Conclusion: There is a growing increase in the number of spinal surgery procedures performed in France before the international pandemic with a clear slowdown afterwards. This trend affects all surgical procedures performed regardless of the indication or type of institution in which the procedures were performed, with a very clear increase in private institutions. There are major disparities in the organization of the positioning of the health care supply.
Unsupervised title and abstract screening for systematic review: a topic modelling approach
Authors: Natukunda Agnes , Muchene Leacky 
Published: May 2022

Abstract
Background: The importance of systematic reviews in collating and summarising available research output on a particular topic cannot be over-emphasized. However, initial screening of retrieved literature is significantly time and labour intensive. Attempts at automating parts of the systematic review process have been made with varying degree of success partly due to being domain-specific, requiring vendor-specific software or manually labelled training data. We propose an unsupervised learning approach to screening documents’ title and abstract during systematic reviews. Methods: We implemented a Latent Dirichlet Allocation-based topic model to derive representative topics from the retrieved documents’ title and abstract. The second step involves defining a score threshold for classifying the documents as relevant for full-text review or not. The score is derived based on a set of search keywords (often the database retrieval search terms). Two systematic review studies were retrospectively used to illustrate the methodology. Results: In one case study (helminth dataset), 69.83% sensitivity compared to manual title and abstract screening was achieved. This is against a false positive rate of 22.63%. For the second case study (Wilson disease dataset), a sensitivity of 54.02% and specificity of 67.03% was achieved. Conclusions: Unsupervised title and abstract screening has the potential to reduce the workload involved in conducting systematic review. While sensitivity of the methodology on the tested data is low, approximately 70% specificity was achieved. Users still have the option to manually review a subset of documents flagged as irrelevant by the automated system.
A Systematic Review of the Efficacy of Herbal and Nutritional Medicines for Improving Cognition in Older Adults With and Without Subjective Cognitive Impairment
Authors: Cave Adele E. , Chang Dennis H. , Münch Gerald W. , Steiner-Lim Genevieve Z. 
Published: May 2022

Abstract
Background: Subjective cognitive impairment (SCI), is conceptualised as the preclinical phase of dementia, and is characterised by a worsening of cognitive functioning, particularly within the area of memory. Due to the increased risk of developing future objective decline, and the lack of pharmacological interventions available to treat SCI, complementary medicines (CMs) are becoming more widely used by older adults, particularly herbal and nutritional medicines. The aim of this systematic review was to describe the study characteristics, methodologies, and intervention efficacy of studies on herbal and nutritional medicines for older adults with and without SCI. Method: Four databases (Cochrane, MEDLINE, CINAHL, and PsycInfo) were searched from database inception until 20 February 2022. Articles were included in the review if they met the following criteria: study population of older adults with and without SCI, herbal and nutritional medicines as an intervention, evaluated cognitive outcomes, and were randomised control trials. Results: Data was extracted from 20/6,006 eligible full-text articles, and risk of methodological bias in accordance with the Cochrane review process for randomised trials, (ROB 2) was assessed. Nine studies used an SCI population, with the remaining eleven, older adults without SCI. Most studies employed parallel, randomised, placebo-controlled designs, and were 12 weeks in length. Sixteen out of twenty studies used a herbal supplement, with most of these using a form of Ginkgo biloba or Bacopa monnieri. Measures of cognition varied across the studies, with 13/20 studies reporting improvements in at least one area of cognitive functioning across time, in the intervention group (compared to placebo). A total of 14/20 studies were deemed as having an overall high methodological risk of bias, 5/20 had some concerns, and only one study (using an SCI population) was assessed as having a low risk of methodological bias. Conclusions: This was the first review to conduct an extensive search of randomised control trials using herbal and nutritional medicines, to improve cognitive functioning in older adults with, and without SCI. Further work needs to be done in classifying and understanding SCI, before future studies can more accurately determine the efficacy of these interventions.
Monitoring the past and future trends of urban thermal comfort conditions through a new methodology
Authors: Çağlak Savaş , Toy Süleyman , Bahadır Muhammet 
Published: May 2022

Abstract
Human thermal comfort representing the satisfaction of mind with ambient air conditions has significant effects on socioeconomic activities. Climate change is affecting thermal comfort conditions (TCCs) negatively. Therefore, it is important to estimate their past and future trends to take accurate measures for mitigation and adaptation efforts in especially urban areas. However, it is difficult to calculate TCCs for future since they are the combined effect of several meteorological parameters on a person outdoor together with her/his own physiological characteristics, which must be evaluated individually. This study aims to determine the TCCs trends in the past compared to the present while estimating the future conditions using a new methodology in the case of Kayseri city in the Interior Anatolia Region of Turkey. As the result of the study, all the change trends considering temporal and spatial results show that thermal comfort conditions signal warmer and higher heat stress in past and future trends. This means human thermal sensation ranges (e.g. very cold) have replaced with the next warmer range and their spatial distribution in percentage has also changed towards warmer. Future predictions have also implied the same change trend and the level of heat stress which has never been experienced in the study area e.g. strong heat stress. Increase in the prevalence of unfavourable thermal comfort conditions causes the decrease in the liveability indicators in especially urban areas, including serious economic loses based on energy consumption, health care expenses and efficiency of activities. It is required that both past and expected future trends be considered in the planning and design works to make cities resilient and have higher adaptive capacity to climate change.
A single center study of two types of upper kidney preservation surgery for complete duplicate kidney in children
Authors: Chu Han , Zhang Xiansheng , Cao Yongsheng , Qifei Deng 
Published: May 2022

Abstract
Objective
To compare the efficacy, advantages and disadvantages of insertable ureteral reimplantation (UC group) and ureteral end-to-side anastomosis (UU group) in the treatment of duplicate kidney, and summarize the clinical experience in diagnosis and treatment.
Methods
Retrospective analysis was performed on 20 cases of duplicate kidney in our hospital from April 2016 to June 2021, including 11 cases of insertable ureteral reimplantation and 9 cases of end-to-side ureteral anastomosis. There were 8 boys, 12 girls, 12 left and 8 right. There were 3 cases of urinary tract infection and 9 cases of urinary incontinence, all of the rest were found by B ultrasound in physical examination. The median age was 33.5 months. Preoperative and postoperative renal pelvis separation, ureteral dilation, operation time and drainage tube indwelling time were compared.
Results
There was no significant difference in the degree of renal pelvis separation and ureter tortuosity before operation between the two groups (P > 0.05), and there was significant difference in the operative time between the two types of operation and in the duration of indwelling drainage tube (P < 0.05), there were significant differences in the degree of hydronephrosis and ureteral dilation before and after the two operations (P < 0.05), while there were no significant differences in the recovery of kidney and ureter after the two operations (P > 0.05).
Conclusion
The two methods have their own advantages and disadvantages, both can be used as the choice of renal sparing therapy for complete duplicate kidney, it is necessary to choose the appropriate method according to the situation of children and the surgical experience of the doctors. Double J tube placement is helpful for finding and protecting ureter intraoperative, without increasing the difficulty of operation, and can prevent anastomosis or ureteral orifice stenosis.
Burden of risks in the analogue and digitally-supported medication use process and potential for solutions to increase patient safety in the hospital: a mixed method study
Authors: Kopanz Julia , Lichtenegger Katharina M. , Schwarz Christine , Motschnig Melanie , Kamolz Lars-Peter , Pieber Thomas , Sendlhofer Gerald , Mader Julia K. , Hoffmann Magdalena 
Published: May 2022

Abstract
Background: Medication errors are common in hospitals. Our aim was to investigate risks of the analogue and digitally-supported medication use process and potential for solutions.Methods: A mixed-method study including a structured literature search, and questionnaires based on the Delphi method was conducted. To identify major risks, a literature search was supplemented by risks from Critical-Incident-Reporting-System cases and risks from experts’ know-how. First, all risks were structured into main and sub-risks and second, risks were grouped into risk clusters. Third, experts were asked to assess risk clusters regarding likelihood of occurrence and impact on patient safety and regarding potential for solutions to strengthen the competence of health care professionals and potential for solutions in digitalization.Results: Overall, 160 main risks and 542 sub-risks were identified. Main risks were grouped into 43 risk clusters. In total, 33 experts (56% female, 50% with >20 years professional-experience) ranked the likelihood of occurrence and the impact on patient safety to 15 top risk clusters regarding the following process steps: admission (n=4), prescribing (n=3), verifying (n=1), preparing/dispensing (n=3), administering (n=1), discharge (n=1), health care professional competence (n=1), and patient (n=1). In total 28 experts (64% female, 43% with >20 years professional-experience) mostly suggested awareness building and training, strengthening of networking, and involvement of pharmacists at point-of-care as solutions to strengthen health care professional competence. For solutions in digitalization a digital medication list, digital warning systems, barcode-technology, and digital support in integrated care were suggested.Conclusions: A multitude of different risks was identified in the medication use process. To increase patient safety and to minimize potential errors, different solutions to strengthen health care professional competence as well as digital solutions exist. As a next step, health care professional competence and digital solutions will be investigated more deeply to derive specific recommendations for intra-hospital clinical practice use.
Exchanges of economic plants along the Land Silk Road
Authors: Wang Guangyan , Chen Qian , Yang Ya , Duan Yuanwen , Yang Yongping 
Published: May 2022

Abstract
Background: The greatest contribution of the Silk Road is to communicate among different countries and nationalities, and promote two-way cultural exchanges between the East and the West. We now have clearer understanding about how material civilization and religious culture of Central Asia and West Asia spread eastward along the Land Silk Road. However, there is controversial about how crops migrate along the Land Silk Road.Results: we summarize archaeology, genetics, and genomics data to explore crop migration patterns. Of the 207 crops that were domesticated along the Land Silk Road, 19 for which genomic evidence was available were selected for discussion.Conclusions: There were conflicting lines of evidence for the domestication of Tibetan barley, mustard, lettuce, buckwheat, and chickpea. The main reasons for the conflicting results may include incomplete early knowledge, record differences in different period, sample sizes, and data analysis techniques. There was strong evidence that Tibetan barley, barley, wheat, and jujube were introduced into China before the existence of the Land Silk Road; and mustard, lettuce, buckwheat, chickpea, alfalfa, walnut, cauliflower, grape, spinach, apple, cucumber, mulberry, and pea spread to China via trade and human migration along the Land Silk Road.