bluuebunny/crossref_metadata_2025_split huggingface dataset:
Supportive Educative Nursing Intervention (SENI) as Intervention in Enhancing Self-Efficacy among Hemodialysis Patients
Authors: Bardah Wasalamah  , Syahirul Alim  , Dony Widyandana  
Published: September 2022

Fluid restriction is the hardest regimen to follow in chronic kidney disease patients receiving hemodialysis, leading to an increase of Interdialytic Weight Gain (IDWG) with several complications. Supportive Educative Nursing Intervention (SENI) Orem's theory is innovative method with the goal of enhancing fluid restriction self-efficacy, and thus have a positive impact on controlling IDWG as an objective marker of fluid restriction adherence. This study aimed to determine the effect of Supportive Educative Nursing Intervention (SENI) on self-efficacy among CKD patients. This study adopted a quasi-experimental, pre and post test with control group design, which was conducted at the RSUD. Dr. M Yunus Bengkulu, Indonesia involving 80 hemodialysis patients. Self-efficacy was measured using the Indonesian Fluid Intake Appraisal Inventory (I-FIAI). Data were collected at baseline, 1 week, and 2 weeks after intervention. Data were analyzed using Repeated ANOVA. Repeated ANOVA test showed a statistically significant difference in mean score self- efficacy (p=0.000). An increase mean score self- efficacy of intervention group was higher than control group (p<0.05). Supportive Educative Nursing Intervention (SENI) Orem's theory increases self- efficacy of hemodialysis patients in fluid restriction.
Sistem Informasi Koperasi Menggunakan Metode Rapid Application Development (RAD)
Authors: Rusmawan Uus 
Published: September 2022

Koperasi merupakan sokoguru perekonomian nasional. Pembagian sisa hasil usaha pada koperasi dilakukan secara adil sesuai dengan jasa usaha masing-masing anggota, yaitu 25% disisihkan untuk dana cadangan jika usaha tersebut berasal dari anggota koperasi dan jika bukan berasal dari anggota, sebanyak 60%. SHU idealnya dialokasikan untuk dana cadangan 35 persen. Jasa anggota 40 persen, dana pengurus 5 persen, dana pengelola koperasi/karyawan 5 persen, dana pendidikan pegawai 5 persen, dana pembangunan lingkungan/pengembangan koperasi 5 persen dam dana sosial 5 persen. Pada implemantasinya, pembagian SHU diserahkan kepada Rapat Anggota Tahunan (RAT) dengan tetap berpegang pada rinsip keadilan dan demokratis. Seiring dengan perkembangan teknologi informasi dan banyaknya permintaan pembuatan aplikasi koperasi yang sesuai dengan kebutuhan user dari berbagai kelompok masyarakat, industri dan perkantoran dengan kebutuhan yang cukup mendesak akibat adanya peraturan pemerintah yang menekankan keberadaannya maka dalam penelitian ini dipilih metode Rapid Application Development (RAD). Proses utama dalam koperasi antara lain dimulai dari pendaftaran, simpanan pokok, simpanan wajib, simpanan sukarela, penarikan dana, pinjaman dana, kredit barang dan pembayaran cicilan sampai pada proses akhir berupa perhitungan SHU. Hal-hal yang sering diminta dalam aplikasi koperasi adalah laporan tunggakan simpanan wajib, laporan tunggakan pinjaman dana, laporan tunggakan cicilan kredit barang, laporan arus kas berupa pemasukan dan pengeluaran biaya-biaya operasional, laporan laba rugi dari hasil unit usaha (penjualan) dan perhitungan Sisa Hasil Usaha (SHU). Aplikasi yang dihasilkan dengan menggunakan metode ini dapat memenuhi kebutuhan pengguna dengan durasi pembuatan yang cukup cepat.
Uterine rupture secondary to undiagnosed placental site trophoblastic tumor: case report
Authors: Hoch Karin , Tavares Arthur Antolini , Benetti-pinto Cristina Laguna , Yela Daniela Angerame 
Published: September 2022

ABSTRACTPlacental site trophoblastic tumor is a rare and malignant form of gestational trophoblastic disease. Its incidence rate is 1/50.000-100.000 pregnancies and accounts for less than 3% of all cases of gestational trophoblastic disease. In addition to its infrequency, the tumor lacks pathognomonic sonographic features, delaying diagnosis until immunohistochemical staining of uterine samples. Early diagnosis is key to avoid metastatic disease. We report a case of an undiagnosed placental site trophoblastic tumor, which caused uterine rupture and hemorrhagic shock.
Redaktionelt forord
Authors: Iversen Ane , Bisgaard Maja , Klindt Mads Peter 
Published: September 2022

Det danske arbejdsmarked er på en og samme tid præget af mangel på kvalificeret arbejdskraft og høj ledighed for dimittender fra en række universitetsuddannelser. Arbejdskraftmanglen ses f.eks. i små- og mellemstore bygge- og anlægsvirksomheder og på sosu-området, hvor det gennem flere år har svært at skaffe faglærte. Imens er ledigheden for nyuddannede akademikere vokset markant. Ifølge en analyse fra tænketanken Mandag Morgen steg dimittendledigheden i 2010’erne fra 16 til 40 %. Højdespringerne i statistikken er historikere, biologer og kommunikationsuddannede, men andre kandidater er også hårdt ramt.
Political Economy of Greenhouse Gas Emissions and Human Security Threat: An Evidence from Niger Delta Region, Nigeria
Authors: Promise Ogele, Eziho 
Published: September 2022

The paper examined the political economy of greenhouse gas emissions and human security threats in the Niger Delta Region, Nigeria. Nigeria is one of the largest producers of crude oil in Africa and flares a greater percent of her gas. The Gas Flare Track indicates that from March 2012 to February 2019, the total carbon dioxide emitted in the five Niger Delta states was estimated at an average of 239.1 million tonnes. Gas flaring by the transnational oil firms is a major contributor to global warming leading to the human security threat in the region. At present, the Niger Delta ecosystem is one of the worst hit by the adverse effects of global warming. The effect of climate change in the Niger Delta region has pushed a greater percentage of its inhabitants into abject poverty. The government is rhetorical and adamant about attending to the socio-economic challenges occasioned by climate change. The continuous neglect and deprivation of access to petrodollar benefits led to the anti-thesis between the Niger Delta inhabitants and the oil companies backed by the federal government in the Region. The aftermath of this struggle is the launching of the artisanal refining of crude oil, which became another source of greenhouse gas emission in the Niger Delta Region. The artisanal refining enterprise, however, received a morale boost from the oil-bearing communities, but unbeknown to them of its environmental impact. The study adopted the externality theory and structural conflict theory as its theoretical construct. The study relied on the qualitative method of data gathering techniques, which include the internet, journals, and books. The study unraveled that gas flaring has become another source of revenue for the Nigerian government, hence cannot end it. The paper recommends amongst others the amendment of the Reinjection Act of 1979 clause that allows multinational oil companies to flare gas.
The Clinical Effect of Triglyceride Glucose Index, an Insulin Resistance Marker, in Predicting Neuropathy Induced by the FOLFOX Chemotherapy Protocol
Authors: Gündoğdu Utku Dönem , Karabağ Funda , Tuğrul Fuzuli 
Published: September 2022

Objective: FOLFOX chemotherapy protocol is a chemotherapeutic agent used in both adjuvant and neoadjuvant chemotherapy of many malignancies such as colon, rectum, stomach, gallbladder, and pancreatic cancer. Despite its therapeutic efficacy, neuropathy is the most dose-limiting factor. The treatment of neuropathy has not been determined yet. Many clinical studies are ongoing for the treatment and prevention of neuropathy. In our study, we aimed to examine the relationship between insulin resistance and neuropathic pain due to FOLFOX chemotherapy protocol.
Materials and Methods: The triglyceride glucose index (TyG-I) before the first chemotherapy, at the 3rd and 6th months of the patients who developed neuropathic pain within 6 months and did not develop neuropathic pain in the patients who underwent FOLFOX chemotherapy protocol due to the diagnosis of cancer, was calculated. Neuropathy pain score was calculated using a validated test, the DN4 neuropathic pain questionnaire. In the pain questionnaire, it was evaluated as neuropathic pain over 4 points. The difference between the patients who developed neuropathic pain and those who did not develop neuropathic pain was evaluated. The effect of TyG-I, an insulin resistance marker, on neuropathic pain was examined.
Discussion and Conclusion: In our study, no difference was found between chemotherapy-induced neuropathic pain and TyG index in patients who underwent FOLFOX chemotherapy protocol. Additional risk factors in the pathophysiology of oxaliplatin-induced neuropathy are limited in the literature. Studies in the literature have not found a relationship between oxaliplatin-induced neuropathy and diabetes. Additional risk factors affecting the development of chemotherapy-induced neuropathy still continue to be the subject of research.
The Effects of Alcohol and Social Isolation on Yawning Behavior in Adult Male Rats, Treated with Opioid Receptor Agonist and Antagonist
Authors: Rafighdoost Fatemeh , Vaezi Gholamhassan , Sharafi Shahram , Shajiee Hooman 
Published: September 2022

The number of 88 rats was chosen, after 21 days, they were ablactated and categorized them as following groups:
The control group 1 has a cage of 8 rats in a social condition. After 6 weeks of saline injection (1mg / kg), the yawning behavior is recorded for 60 minutes. Group 2 in social conditions of receiving ethanol for 2 months, each serving of 600 mg / kg. Group 3 social isolation without treatment with agonist and antagonist, Opioid and alcohol drugs in a separate cage, each cage has one rat. After 6 weeks, It is recorded the yawning was cured for 60 minutes. Group 4 social isolation for 6 weeks and then treatment with alcohol agonist (1200 mg / kg) after 30 minutes of yawing behavior is recorded for 60 minutes. Group 5 Social isolation after 6 weeks of treatment with opioid drugs (5mg / kg of morphine) after 30 minutes of yawing behavior is recorded for 60 minutes. Group 6 social isolation after 6 weeks of morphine + alcohol antagonist treatment after 30 minutes of yawing behavior is recorded for 60 minutes. Group 7 social isolation followed by 6 weeks of treatment with antagonist alcohol (naltrexone), 10 mg / kg, after 30 minutes of yawing behavior is recorded for 60 minutes. Group 8 Social isolation after 6 weeks of treatment with antagonist morphine (naloxone) 1 mg / kg of bad breath after 30 minutes of yawing behavior is recorded for 60 minutes. Group 9 social isolation followed by 6 weeks of treatment with antagonist alcohol + morphine after 30 minutes for 60 minutes of yawing behavior is recorded for 60 minutes. Group 10 social isolation followed by 6 weeks of treatment with antagonist alcohol + morphine antagonist after 30 minutes for 60 minutes of yawing behavior is recorded for 60 minutes. Group 11 Social isolation after 6 treatments with antagonist morphine + alcohol followed after 30 minutes for 60 minutes of yawing behavior is recorded for 60 minutes.
Injection of alcohol chronically reduces yawning, but alcohol injections in conditions of social isolation increase the number of yawns. Antagonist injection of naltrexone prior morphine in conditions of social isolation of yawning. Injection of morphine in conditions of social isolation does not change the number of yawning. Injection of morphine antagonist (naloxone) prior to antagonist of alcohol (naltrexone) in conditions of social isolation increases yawn. Also, the injection of morphine antagonist (naloxone) prior to alcohol into social isolation causes an increase in the number of yawns. Alcohol injection before morphine in conditions of social isolation increases the number of yawns.
It seems that the stress of social isolation by decreasing alcohol and morphine function increases the number of yawns.
Overview on Mixed Connective-Tissue Disease (MCTD)
Authors: Abdulwahed Areej Abdullah , Alsinani Asrar Abdulhameed , Alsaeed Nouf Ali Abdulwahab , Hejazy Asmaa 
Published: September 2022

Most scholars regard mixed connective tissue disease (MCTD) to be a separate illness, whereas some suggest it might be a precursor to a distinct connective tissue disease, such as SLE, SSc, or overlap syndrome. There are no distinct clinical symptoms of MCTD, and clinical presentations vary greatly across individuals. Since the first description, the categorization as a distinct clinical entity has been debated, particularly because individuals with U1 small nuclear ribonucleoprotein particle (snRNP) may eventually match the diagnostic criteria of other 'specified' CTDs. Furthermore, not all investigations have corroborated Sharp's initial definition of MCTD as a benign illness with no organ involvement and a quick response to low-dose glucocorticoids. Mixed connective tissue disease is an uncommon illness with an unknown frequency. Raynaud's phenomenon, arthralgias, swollen joints, esophageal dysfunction, muscular weakness, and sausage-like fingers are the most prevalent clinical signs of mixed connective disease, along with the presence of anti-ribonucleoprotein antibodies. Although several sets of clinical criteria have been offered, there is no agreement on which is the most accurate. MCTD frequently mimics various illnesses and can be readily misdiagnosed. However, many physicians like the Alarcon-Segovia and Villarreal criteria, owing to their simplicity and wide application. Here is little consensus on the initial or long-term therapy of MCTD, particularly the use of low-dose glucocorticoids, antimalarial, and immunosuppressive medications in varied clinical settings. In this article, we we’ll be looking at the disease epidemiology, assessment and treatment.
PENGARUH CUSTOMER PERCEIVED VALUE TERHADAP LOYALITAS TAMU PADA HOTEL BINTANG 4 DAN 5 DI SURABAYA DENGAN KEPUASAN KONSUMEN SEBAGAI MEDIASI
Authors: Silva Elizabeth Amelia Da Costa E. , Hartanto Jane Amelia , Iskandar Vido 
Published: September 2022

The purpose of this research is to understand the influence of customer perceived value on customer loyalty in four- and five-star hotels at Surabaya with customer satisfaction as the mediating variable which were assigned during the COVID-19 pandemic in the city of Surabaya. In this research, researchers used a quantitative method which involved about 200 people who live in Surabaya and experienced staycation as the research’s respondents. This research shows that customer perceived value positively and significantly affects customer satisfaction, customer perceived value positive and significantly affects customer loyalty, customer satisfaction positive and significantly affects customer loyalty, and customer satisfaction fully mediates the relationship of customer perceived value and customer loyalty.

Abstrak
Penelitian dilakukan dengan tujuan untuk mengetahui pengaruh customer perceived value terhadap loyalitas tamu yang menginap di hotel bintang 4 dan 5 yang ada di kota Surabaya dengan kepuasan tamu sebagai variabel mediasi yang diteliti selama pandemi COVID-19 berlangsung di kota Surabaya. Dalam penelitian berikut, peneliti menggunakan metode kuantitatif yang melibatkan 200 masyarakat Surabaya yang pernah melakukan kegiatan staycation sebagai responden. Hasil penelitian ini menunjukkan bahwa customer perceived value berpengaruh positif dan signifikan terhadap kepuasan tamu, customer perceived value berpengaruh positif dan signifikan terhadap loyalitas tamu, kepuasan tamu berpengaruh positif dan signifikan terhadap loyalitas tamu, dan kepuasan tamu memediasi penuh hubungan antara customer perceived value dan loyalitas tamu.
Seasonal variation in risk of anemia among pregnant Nepali women
Authors: Bondevik G.T. , Lie R.T. , Ulstein M. , Kvåle G. 
Published: July 2002

AbstractObjective: We aimed to investigate whether there is any seasonal variation in risk of anemia among pregnant Nepali women. Methods: We studied the hematocrit values in pregnant women (n=5495) attending Patan Hospital, Kathmandu for the first antenatal visit in the 2‐year period from January 1994 until December 1995. In a sub‐sample of subjects (n=2706), additional information was obtained through interviews and clinical examinations. Logistic regression models were used to analyze data. Results: Mean hematocrit values recorded in the monsoon period were significantly lower than hematocrit values recorded in the winter. The prevalence of moderate (hematocrit 25–33%) and severe (hematocrit<25%) anemia was highest in September. Conclusions: We found a clear seasonal variation in risk of anemia, which was associated with rainfall and temperature. The monsoon seems to be a period when interventions may give the most beneficial effects.
Thyrotropin‐releasing hormone immunoreactivity in the brain and the pituitary during Bufo arenarum development
Authors: Miranda Leandro Andrés , Affanni Jorge Mario 
Published: July 2002

AbstractThe ontogeny of the thyrotropin releasing hormone (TRH) neuronal system was evaluated by immunocytochemistry in Bufo arenarum. The first appearance of TRH immunoreactive fibers was at early premetamorphosis. These fibers were found in small numbers and weakly stained in the median eminence and pars nervosa. With the advance of larval development, TRH‐like material stained intensely and tended to aggregate in the median eminence, pars nervosa and pars intermedia. At climax stages immunoreactive fibers and perikarya (weakly stained) were also identified in the preoptic area. In adult specimens TRH perikarya and neuronal fibers were found in the preoptic and infundibular nuclei of the hypothalamus and in the amygdala, septum and diagonal band of Broca of the telencephalon. In addition, TRH neuronal fibers and endings were found in the preoptic‐hypophyseal tract, the external zone of the median eminence, the pars nervosa and pars intermedia. Fibers were absent in the pars distalis. This study represents the first immunocytochemical demonstration of TRH in Bufo species, and serves as a basis for clarification of the neuroendocrine regulation of metamorphosis.
Antihormonal treatment of paraphilic patients in German forensic psychiatric clinics
Authors: Czerny J.-P. , Briken P. , Berner W. 
Published: July 2002

SummaryThe aim of this study was to investigate which antihormonal treatment strategies are used in German forensic psychiatric institutions. Forensic clinics were asked about the number of treated patients. Four hundred seventy-four patients were committed for sex offences; 12% received either CPA (n = 29) or LHRH- agonists (n = 29). Differences in efficacy were small. Several side effects confirm the importance of a protocol for minimizing medical complications.
Expression of Single Chain Antibodies (ScFvs) for c‐myc Oncoprotein in Recombinant Escherichiacoli Membranes by Using the Ice‐Nucleation Protein of Pseudomonassyringae
Authors: Bassi Amarjeet S. , Ding Daniel N. , Gloor Gregory B. , Margaritis Argyrios 
Published: July 2002

AbstractThe ice nucleation protein (INP) is a glycosyl phosphatidylinositol anchored outer membrane protein found in certain Gram‐negative bacteria. In this study, the INP from Pseudomonas syringae was applied as a fusion partner with the single chain antibody fragment (ScFv) against the human oncoprotein c‐myc. Two new plasmids pNinaZ‐myc and pNinaZScFv‐BsaA1 were constructed and cloned into Escherichia coli JM109. The expression of the fusion protein was successfully demonstrated in the cloned cells. The fusion proteins had no effect on the viability of the host cells. Ice nucleation activity measurements and flow cytometry studies were followed to investigate the membrane expression of the fusion protein.
Improving the Cytochrome P450 Enzyme System for Electrode‐Driven Biocatalysis of Styrene Epoxidation
Authors: Mayhew Martin P. , Reipa Vytautas , Holden Marcia J. , Vilker Vincent L. 
Published: July 2002

AbstractCytochrome P450 enzymes catalyze a vast array of oxidative and reductive biotransformations that are potentially useful for industrial and pharmaceutical syntheses. Factors such as cofactor utilization and slow reaction rates for nonnatural substrates limit their large‐scale usefulness. This paper reports several improvements that make the cytochrome P450cam enzyme system more practical for the epoxidation of styrene. NADH coupling was increased from 14 to 54 mol %, and product turnover rate was increased from 8 to 70 min−1 by introducing the Y96F mutation to P450cam. Styrene and styrene oxide mass balance determinations showed different product profiles at low and high styrene conversion levels. For styrene conversion less than about 25 mol %, the stoichiometry between styrene consumption and styrene oxide formation was 1:1. At high styrene conversion, a second doubly oxidized product, α‐hydroxyacetophenone, was formed. This was also the exclusive product when Y96F P450cam acted on racemic, commercially available styrene oxide. The α‐hydroxyacetophenone product was suppressed in reactions where styrene was present at saturating concentrations. Finally, styrene epoxidation was carried out in an electroenzymatic reactor. In this scheme, the costly NADH cofactor and one of the three proteins (putidaredoxin reductase) are eliminated from the Y96F P450cam enzyme system.
Production of Cycloisomaltooligosaccharides from Dextran Using Enzyme Immobilized in Multilayers onto Porous Membranes
Authors: Kawakita Hidetaka , Sugita Kazuyuki , Saito Kyoichi , Tamada Masao , Sugo Takanobu , Kawamoto Hiroshi 
Published: July 2002

AbstractAnion‐exchange porous hollow‐fiber membranes with a thickness of about 1.2 mm and a pore size of about 0.30 μm were used as a supporting matrix to immobilize cycloisomaltooligosaccharide glucanotransferase (CITase). CITase was immobilized to the membrane via anion‐exchange adsorption and by subsequent enzymatic cross‐linking with transglutaminase, the amount of which ranged from 3 to 110 mg per gram of the membrane. The degree of enzyme multilayer binding was equivalent to 0.3–9.8. Dextran, as the substrate, was converted into seven‐ to nine‐glucose‐membered cycloisomaltooligosaccharides (CI‐7, ‐8, and ‐9) at a maximum yield of 28% in weight at a space velocity of 10 per hour during the permeation of 2.0% (w/w) dextran solution across the CITase‐immobilized porous hollow‐fiber membrane. The yield of CIs increased with increasing degree of CITase multilayering.
Crystallization and X‐ray Diffraction of Crystals Formed in Water‐Plasticized Amorphous Lactose
Authors: Jouppila Kirsi , Kansikas Jarno , Roos Yrjö H. 
Published: July 2002

AbstractEffects of storage time and relative humidity on crystallization and crystal forms produced from amorphous lactose were investigated. Crystallization was observed from time‐dependent loss of sorbed water and increasing intensities of peaks in X‐ray diffraction patterns. The rate of crystallization increased with increasing storage relative humidity. Lactose crystallized mainly as α‐lactose monohydrate and anhydrous crystals with α‐ and β‐lactose in a molar ratio of 5:3. The results suggested that the crystal form was defined by the early nucleation process. The crystallization data are important in modeling of crystallization phenomena and prediction of stability of lactose‐containing food and pharmaceutical materials.