bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis SWOT pembelajaran daring era pandemi covid-19 pada sekolah dasar
Authors: Citraningsih Diningrum , Wiranata Rz. Ricky Satria 
Published: July 2022

Penelitian ini bertujuan untuk mengetahui SWOT yaitu strengths (kekuatan), weakness (kelemahan), opportunity (peluang), threats (ancaman) dalam pembelajaran daring era pandemic covid-19 pada jenejang sekolah dasar. Penelitian ini merupakan penelitian library research yang mana menggunakan sumber data berupa buku, artikel atau jurnal. Hasil penelitian yaitu pada dimensi strengths (kekuatan) menjelaskan tentang motivasi dari guru dan orang tua kepada peserta didik, dukungan fasilitas penunjang pembelajaran (handphone, laptop, kuota), penggunaan aplikasi portal rumah belajar Kemendikbud, menambah keahlian dan kreativitas guru dan peserta didik, dan pelaksanaan program pendampingan belajar di rumah. Pada dimensi weakness (kelemahan) menjelaskan tentang tingkat kedisiplinan peserta didik dalam pembelajaran daring belum maksimal, kejenuhan peserta didik dengan kegiatan monoton, kurangnya waktu interaksi peserta didik dengan guru, kurangnya pengawasan dari orang tua pada anak, minimnya tingkat literasi digital. Pada dimensi opportunity (peluang) menjelaskan tentang pengembangan wawasan, pengetahuan dan keterampilan bagi guru dan peserta didik, meningkatkan kerja sama antara orang tua dan guru. Pada dimensi threats (ancaman) menjelaskan tentang penyediaan kuota internet dan biaya pembelajaran daring, jaringan internet yang kurang stabil, minimnya fasilitas pendukung berupa handphone atau laptop, kesehatan dan ketahanan tubuh. This study aims to determine SWOT, strengths, weaknesses, opportunities, threats in online learning in the era of the covid-19 pandemic at the elementary school. This research uses a library research which uses data sources in the form of books, articles or journals. The results of the study are on the strengths dimension explaining the motivation of teachers and parents to students, support for learning support facilities (mobile phones, laptops, quotas), the use of the Ministry of Education and Culture's home learning portal application, increasing the skills and creativity of teachers and students, and implementing mentoring programs. study at home. The weakness dimension explains the level of student discipline in online learning is not maximized, student saturation with monotonous activities, lack of interaction time between students and teachers, lack of parental supervision of children, lack of digital literacy levels. The opportunity dimension describes the development of insight, knowledge and skills for teachers and students, increasing cooperation between parents and teachers. The threats dimension describes the provision of internet quota and online learning costs, unstable internet network, lack of supporting facilities in the form of mobile phones or laptops, health and body resistance.
A Data-Driven Reference Standard for Adverse Drug Reaction (RS-ADR) Signal Assessment: Development and Validation
Authors: Lee Suehyun , Lee Jeong Hoon , Kim Grace Juyun , Kim Jong-Yeup , Shin Hyunah , Ko Inseok , Choe Seon , Kim Ju Han 
Published: July 2022

BackgroundPharmacovigilance using real-world data (RWD), such as multicenter electronic health records (EHRs), yields massively parallel adverse drug reaction (ADR) signals. However, proper validation of computationally detected ADR signals is not possible due to the lack of a reference standard for positive and negative associations.ObjectiveThis study aimed to develop a reference standard for ADR (RS-ADR) to streamline the systematic detection, assessment, and understanding of almost all drug-ADR associations suggested by RWD analyses.MethodsWe integrated well-known reference sets for drug-ADR pairs, including Side Effect Resource, Observational Medical Outcomes Partnership, and EU-ADR. We created a pharmacovigilance dictionary using controlled vocabularies and systematically annotated EHR data. Drug-ADR associations computed from MetaLAB and MetaNurse analyses of multicenter EHRs and extracted from the Food and Drug Administration Adverse Event Reporting System were integrated as “empirically determined” positive and negative reference sets by means of cross-validation between institutions.ResultsThe RS-ADR consisted of 1344 drugs, 4485 ADRs, and 6,027,840 drug-ADR pairs with positive and negative consensus votes as pharmacovigilance reference sets. After the curation of the initial version of RS-ADR, novel ADR signals such as “famotidine–hepatic function abnormal” were detected and reasonably validated by RS-ADR. Although the validation of the entire reference standard is challenging, especially with this initial version, the reference standard will improve as more RWD participate in the consensus voting with advanced pharmacovigilance dictionaries and analytic algorithms. One can check if a drug-ADR pair has been reported by our web-based search interface for RS-ADRs.ConclusionsRS-ADRs enriched with the pharmacovigilance dictionary, ADR knowledge, and real-world evidence from EHRs may streamline the systematic detection, evaluation, and causality assessment of computationally detected ADR signals.
Adesão à terapia farmacológica em pacientes com hanseníase
Authors: Oliveira Josiéle Gomes de , Oliveira Isabella Alcantara de , Valério Danielle Conceição de Barros Costa , Santos Débora Aparecida da Silva , Alves Rauni Jandé Roama , Goulart Letícia Silveira 
Published: July 2022

A hanseníase é uma doença infecciosa crônica causada pelo Mycobacterium leprae, considerada um grave problema de saúde pública. A adesão à terapia farmacológica contribui para a qualidade de vida do paciente e para a interrupção da cadeia de transmissão da doença. Este trabalho objetivou analisar a adesão à poliquimioterapia em pacientes com hanseníase acompanhados em um serviço de atendimento especializado do município de Rondonópolis (MT). Trata-se de um estudo descritivo de abordagem quantitativa. Participaram da pesquisa 63 pacientes com diagnóstico de hanseníase, acompanhados no Serviço de Atendimento Especializado do Município de Rondonópolis. Para analisar a adesão, utilizou-se o teste de Morisky-Green. Foram classificados como aderentes ao tratamento 31 pacientes (49,2%) no total. As menores frequências de adesão foram observadas em mulheres, na faixa etária de 51 a 59 anos, de cor autodeclarada branca, renda familiar superior ou igual a dois salários mínimos, com até oito anos de estudo, sem companheiros e que possuíam rede de esgoto em suas residências. Observou-se diferença estatística para as variáveis sexo (p = 0,036), modo de detecção (p = 0,008) e forma clínica (p = 0,028). Os resultados indicaram baixa adesão à poliquimioterapia. Mulheres, pacientes com modo de detecção do tipo encaminhamento ou exames de coletividade, com forma clínica indeterminada, tuberculoide ou virchowiana são menos aderentes à poliquimioterapia. Os resultados indicam a necessidade de adoção de medidas que busquem promover melhor aceitação à terapia farmacológica entre os pacientes com hanseníase.
PEMANGKASAN DAUN PADA POSISI SPESIFIK TERHADAP HASIL TANAMAN JAGUNG
Authors: Mapegau Mapegau , Fitriani Miranti Sari , Hayati Islah , Rumita Sari Puput 
Published: July 2022

Pemangkasan daun pada posisi tertentu pada batang, merupakan salah satu teknik yang dapa dilakukan untuk meningkatkan hasil tanaman jagung. Penelitian ini bertujuan untuk mendapatkan posisi pemangkasan daun pada batang yang tepat untuk meningkatkan hasil tanaman jagung (Zea mays L.). Penelitian dilaksanakan pada bulan Juli-Oktober 2020 di Kelurahan Simpang, Kecamatan Berbak, Kabupaten Tanjung Jabung Timur, Provinsi Jambi. Penelitian menggunakan Rancangan Acak Kelompok (RAK) dengan 5 ulangan. Perlakuan pemangkasan yang cobakan berdasrkan posisi daun pada batang adalah: Tanpa pemangkasan (kontrol/p0), pemangkasan 3 helai daun pada possis dekat permukaan tanah (p1), pemangkasan 3 helai daun pada posisi di bawah tongkol (p2), pemangkasan 3 helai daun pada posisi sekitar tongkol (p3), dan pemangkasan 3 daun pada posisi diatas tongkol (p4). Jagung ditanam dengan jarak tanam 80 cm x 20 cm pada petakan berukuran 4 m x 2 m. Hasil penelitian menunjukkan bahwa perlakuan pemangkasan daun berpengaruh nyata pada berat tongkol kering berkelobot, berat 100 butir biji kering, dan hasil biji kering, tetapi tidak berpengaruh terhadap berat tongkol kering tanpa kelobot. Pemangkasan 3 helai daun pada posisi di bawah tongkol dapat meningkatkan berat tongkol kering berkelobotsebesar 14,91%, berat 100 butir biji kering sebesar16,27%, dan hasil biji kering sebesar 35,07% dibandingkan tanpa pemangkasan. Pemangkasan 3 helai daun pada posisi sekitar tongkol dapat meningkatkan berat tongkol kering berkelobot sebesar 28,00%, berat 100 butir biji kering sebesar 19,19%, dan hasil biji kering 27,96% dibandingkan tanpa pemangkasan.
Diagnostic value of Epstein – Barr virus DNA quantification in blood leukocytes in children with infectious mononucleosis
Authors: Popkova M. I. , Filatova E. N. , Soboleva E. A. , Bryzgalova D. A. , Kulova E. A. , Sakharnov N. A. , Utkin O. V. 
Published: July 2022

Aim. To determine the threshold value of the Epstein-Barr virus (EBV) viral load (VL) in blood leukocytes to improve the laboratory diagnostics of infectious mononucleosis in children.Materials and methods. EBV DNA quantification in blood leukocytes in children aged 1-17 years (n=163) was determined by real-time polymerase chain reaction. VL were compared in groups of EBV mononucleosis (n=67), non-EBV mononucleosis (n=25) and healthy donors (n=25). Threshold was determined based on VL data from children with active and latent EBV infection. The R program and the RStudio environment were used for satistic analysis.Results. EBV DNA is found in blood leukocytes in infectious mononucleosis not associated with EBV and in healthy virus carriers, however VL in these groups is significantly lower than in patients with EBV mononucleosis (p<0.001). The threshold value was determined – 41 copies/105 cells (or 1.6 lg of EBV DNA/105 cells), which was characterized by acceptable values of specificity and sensitivity (0.90 and 0.85, respectively) of laboratory diagnostics. High EBV VL (equal to or above the set threshold) is associated with an 8.5-fold increased risk of detecting active EBV infection compared to children who have a low VL (below a set threshold) (RR 8.5; 95% CI: 3.7–19.7, p<0.001).Conclusion. In general, the results obtained create prerequisites for more intensive implementation of quantitative studies of EBV DNA in blood leukocytes, both in the context of improving the early diagnosis of infectious mononucleosis and its etiological interpretation, and in terms of detailing the features of the course of EBV infection.
Personalized therapy with bacteriophages of digestive diseases
Authors: Gonchar N. V. , Ermolenko K. D. , Skripchenko N. V. 
Published: July 2022

Current insights into the close relationship between human health and the gut microbiota, as well as recent advances in molecular biology suggesting a significant role for gut viromas, have encouraged research into the therapeutic usefulness of bacteriophages.The purpose of this review is to consider the prospects for the use of bacteriophages for the correction of the gut microbiota and therapy of digestive system diseases.The review describes the basics of phage biology, peculiarities of bacteriophage virome of the intestine in gastroenterological pathology; it highlights modern methods of phage-based therapy and prevention, considers problems of phage therapy and ways to overcome them. It is shown that the use of phages can become a key personalized approach to the treatment and prevention of infectious and non-infectious gastroenterological diseases.
Indirect bonding: an in-vitro comparison of a Polyjet printed versus a conventional silicone transfer tray
Authors: Hofmann Eva C. , Süpple Julia , von Glasenapp Julius , Jost-Brinkmann Paul-Georg , Koch Petra J. 
Published: July 2022

ABSTRACT

Objectives
To investigate and compare transfer accuracy between a Polyjet printed indirect bonding (IDB) tray (SureSmile, Dentsply Sirona, Richardson, TX, USA) and a conventional two-layered silicone tray.

Materials and Methods
Plaster models of 24 patients were digitized with an intraoral scanner, and brackets and tubes were positioned virtually on the provider's homepage. IDB trays were designed over the planned attachments and Polyjet 3D-printed. For the conventional tray, brackets and tubes were bonded in their ideal positions manually before fabricating a two-layered silicone tray. For both trays, attachments were transferred indirectly to corresponding models. A second scan was performed of each bonded model to capture actual attachment positions, which were then compared to initial bracket positions using Geomagic Control (3D Systems Inc., Rock Hill, SC, USA). Linear and angular deviations were evaluated for each attachment within a clinically acceptable range of ≤0.2 mm and 1°. A descriptive statistical analysis and a mixed model were executed.

Results
Both trays showed highest accuracy in the orobuccal direction (99.5% for the 3D-printed tray and 100% for the conventional tray). For the 3D-printed tray, most frequent deviations were found for torque (15.4%) and, for the silicone tray, for rotation (1.9%). A significant difference was observed for angular measurements (P = .004) between the trays.

Conclusions
Transfer accuracy of Polyjet printed IDB tray is not as high as transfer accuracy of the conventional silicone tray, though both trays show good results and are suitable for clinical application.
Conciencia verde y ley de emprendimiento; el camino de la sostenibilidad
Authors: MARTINEZ LARRARTE EDUARDO , Hernández Flechas Sonia 
Published: July 2022

La crisis estructural del capitalismo, el Carácter inestable, imprevisible de la crisis ha dado apertura de posibilidades nuevas, la experiencia humana de la basculación[1] que según el investigador (Jerome baschet), serán la base para el auge de nuevas economías más sostenibles, por su parte el modelo E3ME tratado ampliamente en las sesiones del CEPAL (Comisión económica para Latinoamérica y el caribe) durante el mes de octubre del año 2020, propone como centro de su estrategia, la innovación como ancla, a su vez se vale de las variables clima, energía y economía, todo en un ciclo que se repite y en donde se plantean renovaciones constantes[2].
Dentro del emergente proceso de conversión económica, la reciente pandemia ha alterado estos planes, dando lugar a la aceleración forzosa de las empresas hacia esta conversión, propiciando también nuevas oportunidades económicas. Así mismo, Las patologías previas padecidas por las empresas tales como el endeudamiento, desabastecimiento, y caducidad de su relevancia en el mercado; son el punto de partida donde se ubicará la innovación de las mismas, y su sentimiento de crisis inevitable.

[1] Este termino hace referencia, a
[2] Para ampliar este concepto remitirse a; https://www.camecon.com/how/e3me-model/
El queso y los gusanos: un modelo de historia crítica para el análisis de las culturas subalternas
Authors: Aguirre Rojas Carlos Antonio 
Published: July 2022

"A partir de un análisis preciso, la idea de una religión "popular", ahistórica e inmóvil, se revela como insostenible. En su lugar hay que plantear la idea compleja de una lucha entre religión de las clases hegemónicas y religión de las clases subalternas, conformada como toda lucha, por confrontaciones abiertas, por compromisos, por situaciones de una paz forzada, por guerrillas".CARLO GINZBURG, "Premessa Giustificativa" en Quaderni Storici, num. 41, 1979.
El estado democrático de derecho y los derechos fundamentales
Authors: Durango Álvarez Gerardo 
Published: July 2022

El objetivo de este ensayo es realizar un acercamiento a los postulados que sobre los derechos fundamentales realiza Habermas, esto mediante un postulado de gran referencia teórico-argumentativa como el esgrimido por el autor, en el "principio discursivo". Para analizar la legitimación basada en los derechos fundamentales, Habermas parte de un sentido referido a la legitimación de un orden político y, particularmente, al orden político del Estado constitucional democrático. Habermas explica dicha relación a través de un nexo interno entre democracia y derechos humanos. Se pregunta cuáles son los derechos fundamentales que deben otorgarse recíprocamente ciudadanos libres e iguales si quieren regular legítimamente su vida común con los medios del derecho positivo.
El jurado de conciencia
Authors: Franco Jaramillo Héctor Ignacio 
Published: July 2022

Cada vez está más cerca el 1 de enero de 2005, fecha en la cual, según lo dispone el Acto Legislativo 03 de diciembre 19 de 2002, debe entrar a regir el nuevo sistema de procesamiento penal: el sistema acusatorio. En el acto legislativo y en el proyecto de Código de Procedimiento Penal que desarrolla dicho sistema de procesamiento, si bien es cierto el Jurado de Conciencia se enuncia como uno de los órganos llamados a administrar justicia, no se le asigna esquema de funcionamiento alguno -número de integrantes, forma de elección, posesión, instalación, operatividad, etc.- como tampoco se señala qué delitos estarían sometidos al juzgamiento con participación de dicha Institución.
¿Un nuevo derecho para una sola justicia protectora del derecho laboral y de la seguridad social en Colombia?
Authors: Mejia Restrepo Alfonso Tito 
Published: July 2022

El interrogante que se hace, sobre si en Colombia nos estamos viendo abocados a tener dos sistemas de justicia diferentes, o, por el contrario, es sólo un sistema de justicia protectora de los derechos con una nueva interpretación de las disposiciones, dándole su verdadero sentido y alcance conforme con la Constitución Política a partir de 1991, tiene plena actualidad, y es de gran linportancia siempre que abotdemos cualquiera de los temas del derecho, en especial, los correspondientes al derecho laboral y a la seguridad social integral, puesto que estos últimos conllevan implícitamente el respeto por los derechos y la dignidad humana.
Las reformas constitucionales en México, como objeto de la acción de inconstitucionalidad
Authors: Rizo Magaña Elva 
Published: July 2022

El control judicial de las leyes apareció hace doscientos años con el caso Marbury vs. Madison,en los Estados Unidos, cuando el Tribunal Supremo norteamericano, presidido por el juez Marshall, consagró, en 1803, con ese emblemático caso, el principio jurídico de la supremacía constitucional, por encima de la soberanía política del Congreso. La sentencia expresó, jurídicamente, un claro conflicto político entre el saliente Presidente Adams -federalista- y el entrante Jefferson -republicano o antifederalista-.
Azar, igualdad y biotecnología
Authors: Ruiz Miguel Alfonso 
Published: July 2022

Las relaciones que pueden establecerse entre azar, igualdad y biotecnología suscitan un debatebien prolijo en el campo de la filosofía moral, generando dudas y numerosas discusiones. La reflexión sobre el alcance moral de ciertas hipotéticas posibilidades que podría brindar la biotecnología, permite iluminar el debate sobre la suerte bruta en materia de justicia distributiva.
Aspectos fenológicos de las progenies de maracuyá silvestre BRS Maracujá Maçã, BRS Pérola do Cerrado y BRS Sertão Forte
Authors: Neves da Silva Clotilde , Faleiro Fábio Gelape , Da Silva Oliveira Jamile , Vilela Junqueira Nilton Tadeu 
Published: July 2022

En este trabajo, el objetivo fue evaluar el comportamiento fenológico de tres progenies de maracuyá silvestre de septiembre de 2015 a agosto de 2016, en las condiciones del Cerrado do Planalto Central, en Planaltina - DF. Se analizaron los períodos de floración y fructificación en condiciones naturales de las progenies BRS Maracujá Maçã (BRS MM), BRS Pérola do Cerrado (BRS PC) y BRS Sertão Forte (BRS SF) para verificar el inicio, duración y terminación de las diferentes fenofases. . Las observaciones se realizaron semanalmente en campo, realizándose registros fotográficos digitales de flores y frutos de plantas de cada descendencia marcadas aleatoriamente en cada zona, con el fin de identificar los estados reproductivos y cambios morfológicos durante la fenología reproductiva de la especie. El mayor número de botones florales y flores por metro de espaldera obtenido por las progenies BRS PC, BRS MM y BRS SF fueron 284 (febrero), 180 (marzo) y 188 (abril), respectivamente. El mayor número de frutos contados para las progenies BRS PC, BRS MM y BRS SF fueron 75 (marzo), 91 (abril) y 77 (agosto), respectivamente. El período de floración y fructificación en las condiciones del Cerrado do Planalto Central para estas tres progenies en estudio es del tipo continuo, en el que hay producción de flores y frutos durante todo el año.
Determination of treatment options for Class III malocclusions in adult patients based on cephalometric values: a systematic review
Authors: Sivarajan Saritha , Zakaria Nor Nadia , Azmily Noor Asyikin , Wey Mang Chek , El-Ghafour Mohamed Abd , Salah Fayed Mona M. 
Published: July 2022

Abstract

Objective
The present systematic review aimed to determine cephalometric values that may be used as a guide in deciding between orthodontic camouflage and orthognathic surgery to treat a Class III malocclusion in adults. In addition, a secondary aim was to identify treatment complications and aesthetic perceptions by laypersons/orthodontists.

Methods
Without a language restriction, an electronic search of six databases and a hand search of three orthodontic journals were performed until September 2021. All studies comparing orthodontic camouflage and orthognathic surgery in Class III malocclusion patients, were included. Data extraction was carried out independently by two authors with disagreement resolved by a third author. The risk of bias related to individual studies was appraised using a modified version of the STROBE checklist. The results were summarised qualitatively, and no meta-analysis was undertaken due to the high heterogeneity between the studies.

Results
With the quality of evidence ranging from moderate to high, six retrospective studies were included. A cephalometric analysis comprising the Holdaway angle, overjet, the Wits appraisal, lower incisor inclination, the maxillary-mandibular ratio, overbite, gonial angle and an additional combination were used as a guide. No treatment complications were reported. One study examined the perception of facial profile attractiveness in borderline surgical Class III malocclusions and found no difference in outcome and significant improvements in both camouflage and surgical groups.

Conclusion
The existing evidence is insufficient to identify a cephalometric parameter threshold in deciding between orthodontic camouflage and orthognathic surgery. PROSPERO database protocol no. CRD42020165164.