bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Cross Section From the Consumer Perspective on Sustainable Nutrition: Consumer Awareness and Motivation Status
Authors: Ersoy Nesli 
Published: August 2022

Abstract
Sustainable diets and food production systems are important for healthy life and future generations. This goal should be reachable by consumer motivations. The study aim is the evaluation of awareness and knowledge of sustainability and logo/claims related with sustainability. Participants’ knowledge about sustainability definition and logos/claims related to sustainability were assessed by an online-questionnaire. The questionnaire involved the calculation of annual dietary carbon emissions (kg), nitrogen waste (g), and water consumption (L). Four hundred-two volunteers participated in the study (male: 24.9%; female: 75.1). Only 44 participants (10.9%) explained what sustainable nutrition definition, correctly. The rates of knowledge about logos were quite low; 29.4% for organic product logo; 26.6% for Good farming practice logo; 86.1% for Recycle logo; and 8.0% for Eco-label logo, respectively. The education status of participants affected to knowledge of logo/claim ratio (p<0.05).Ethic production statements and environmental impact statement information were taken attention of participants’ ratio of 33.6% and 34.1%, respectively. The mean dietary carbon emission of participants was 551.0±343.6 kg/year, which was 81% of the upper limit (680 kg/year). The mean nitrogen waste was 3238.8±4620.9 g/year and mean water consumption was 91538.7±157537.9 L/year. Mediterranean diet model carbon emission and nitrogen waste were higher than other diet models, omnivore diet models had more water consumption than other diet models. But these differences were not found statistically significant (p>0.05).Sustainable nutrition can be achieved via consumers’ awareness. Food industry and government should encourage the people about promotion of sustainable food preferences.
Temporal dynamics of hepato-metabolic variables, pH metrics and electrolyte homeostasis throughout the transition period in mithun (Bos frontalis) cows
Authors: Joshi Vivek , Chamuah J. K. , R. Vikram , Ezung Lipenthung Y , Vupru K. , Lalzampuia H. , Khan M. H. 
Published: August 2022

Abstract
Mithun is a rare bovid exclusively found in high altitude rainforests of northeast India and remains as one of the least studied and neglected species. This is the first study aimed to monitor the effect of transition period on lipid biology, metabolic variables, pH metrics and serum electrolytes of mithun cows reared under semi-intensive system. The study was based on ante-partum (-3 weeks) and post-partum (+1, +2, +3 weeks) appraisal of blood, urine and ruminal fluid from fifteen pregnant mithun cows in last trimester (test group) and fifteen non-pregnant mithun cows (controls). Significantly lowered (P<0.05) total cholesterol and triglycerides were observed in mithun cows immediately after calving however, their levels increased during 1st to 3rd week post-partum. There was a consistent rise (P<0.05) in AST activity at week 0 and +1 while it began to decrease from week +1 to +3. During week 0 and 1, significant decrease (P<0.05) in serum calcium, magnesium, sodium and iron was recorded in transitioning mithun. However, these electrolytes gradually increased from week +1 to +3. Moreover, transitioning cows self-regulated their blood, urinary and ruminal pH without deviation around calving and during the first week of lactation. It is inferred that although transitioning mithun cows are predisposed to mild hypocalcemia, hypomagnesemia and hyponatremia for few weeks post-partum, lipomobilization is a hallmark of their transition period to mitigate energy demands of lactation. Transitioning mithuns exhibit superior metabolic adaptability by rapid restoration of the hepato-metabolic dynamics and pH metrics to normal without supplementation of glucogenic precursors.
Evaluation of Provincial Carbon-neutral Capacities in the Yellow River Basin Using DPSIR
Authors: Xu Jian , Wang Haiying , Zhao Keyu , Li Zhi 
Published: August 2022

Abstract
The Yellow River basin plays an important role in China's economic and social development and ecological security. To study the changes in the trend and driving mechanisms of the carbon-neutral capacity of the Yellow River basin and provide a theoretical reference value for a comprehensive realization of carbon neutrality in China in 2060, the corresponding subsystems based on the driving-force-pressure-state-impact-response (DPSIR) model framework were established. Furthermore, a DPSIR index system, which consisted of 39 factors reflecting the carbon-neutrality capacity and ecological environment state of the Yellow River basin, was proposed. The DPSIR subsystem layers’ weights were determined using an expert evaluation method. The global entropy method was used to obtain the weights of the 39 indicators, the evaluation model of carbon-neutral capacity was proposed to calculate the comprehensive evaluation value of the provincial carbon-neutral capacities comprehensive evaluation Index (CCCEI) in the Yellow River basin. Our results indicate that, from the perspective of the DPSIR subsystems, the evaluation value of the carbon-neutral capacity driving subsystem in the Yellow River basin exhibited an overall upward trend from 2008 to 2019. However, the evaluation value of the carbon-neutral capacity pressure subsystem decreased slightly in some years, while the overall trend increased marginally. The carbon-neutral capacity status subsystem evaluation value was at a lower level and requires further improvement. The evaluation value of the carbon-neutral capacity impact subsystem had a certain fluctuation, and the evaluation value of the carbon-neutral capacity response subsystem improved rapidly and steadily afterward. The final results indicated that, from 2008 to 2019, the carbon-neutral capacities of the provinces in the Yellow River basin were in a state of rapid development and had achieved a grade leap. However, seven provinces had carbon-neutral capacity levels at Grade III standard in 2019, thereby leaving scope for substantial improvement.
Maintaining pioneer and exemplary: Model worker CEO and corporate green innovation
Authors: LV Jingxin 
Published: August 2022

Abstract
Drawn on the upper echelons theory, this study analyzes the impact effect and potential mechanism of model worker chief executive officer (CEO) on corporate green innovation. The research results show that model worker CEO has a significant positive impact on corporate green innovation, and the research conclusion is still valid after a series of endogenous analysis and robustness tests. The exploration of the potential mechanism suggests that strengthening environmental ethics and optimizing resource allocation are two potential mechanisms for model worker CEO to influence green innovation. The results of heterogeneity analysis show that model worker CEO is more conducive to promoting green innovation in firms with abundant redundant resources, lower ownership concentration, and state-owned enterprises. In the context of higher market complexity and marketization degree, the positive relationship is more pronounced. From the perspective of CEO cultural background, this study provides new insights into corporate green innovation drivers and can serve as a reference basis for the improvement of CEO selection mechanism, the formulation of corporate green innovation strategy, and the evaluation of stakeholders’ decision-making.
Time to vasoactive agents initiation, restricted volume resuscitation effect on fluid balance and clinical outcomes in children with septic shock
Authors: Sanguanngam Siripen , Kongkiattikul Lalida , Samransamruajkit Rujipat 
Published: August 2022

Abstract
Background
Several studies have shown that positive fluid balance is associated with worse outcomes in pediatric severe sepsis and septic shock patients. Early vasopressor administration in children with septic shock after ≤ 40 cc/kg of fluid bolus may be beneficial.
Methods
This is a retrospective analytic study in children with septic shock (aged between one month and 18 years from 2012–2020.) They were recruited at a referral tertiary university hospital in Bangkok, Thailand and were treated with either restricted volume resuscitation (≤ 40 cc/kg of fluid bolus) combined with vasopressors or standard volume resuscitation. The clinical effect on fluid balance and other outcomes were measured.
Results
One hundred and forty-three patients were diagnosed with septic shock. Ninety-three patients started vasoactive agents at ≤ 40 mL/kg (study group) compared to 50 patients who started the vasopressor drugs after 40 mL/kg of fluid bolus (control group). Volume administered at 6, 24 and 48 hours in study group was significantly less than control group (p < 0.001). There was a trend of higher %Fluid Overload (%FO) at 24 to 72 hours in control group but it was not statistically significant. %FO at 24 hours was significantly correlated with time initiation of vasoactive agent (R2 = 0.17, p = 0.03) and length of PICU stay (R2 = 0.2, p = 0.02). In addition, the multivariate analysis showed that initial serum level of albumin was less than 3 g/dL and positive %FO of more than 10% at 24 hours significantly increased mortality by 6.3 (95% CI, 1.25 to 32.12; p = 0.03) and 6.1 folds (95% CI, 1.47 to 25.46; p = 0.01), respectively.
Conclusion
There was a trend of decreasing %FO overtime in study group compared to the control group. Time initiation of vasoactive agent and %FO significantly correlated with prolonged PICU stay.
Using Developmental Regression to Reorganize the Clinical Importance of Autistic Atypicalities
Authors: Mottron Laurent , Gagnon David , Zeribi Abderrahim , Douard Elise , Courchesne Valerie , Huguet Guillaume , Jacquemont Sébastien , Loum Mor 
Published: August 2022

Abstract
Early regression (ER) is often reported in autistic children with a prototypical phenotype, and has been proposed as possible pathognomonic sign, present in mot autistic children. Despite the uncertainties attached to its definition and report, using ER to anchor the autism phenotype could help identify the signs contributing the best to the autism diagnosis. We extracted retrospective data from 1,547 autistic children between the ages of 6 and 18 years from the Simons Simplex collection. Logistic regression identified the atypicalities significantly associated with a history of ER. Stepwise variable selection using logistic regression analysis followed by a bootstrap procedure of 1000 iterations identified the cluster of atypicalities best associated with ER. Linear and logistic regressions measured the association between combinations of atypicalities within the identified cluster and adaptative behaviors, diagnostic areas severity and categories. Seven atypicalities significantly increased the likelihood of having experienced ER (OR = 1.73 to 2.13). Four (“hand leading – ever”, “pronominal reversal – ever”, “never shakes head at age 4 to 5” and “stereotypic use of objects or interest in parts of objects – ever”), when grouped together, best characterized the phenotype of verbal autistic children with ER. This clustering of signs was associated with certain persistent language difficulties, higher summary scores on a diagnostic scale for autism and greater odds of receiving an “autistic disorder” diagnosis instead of another PDD diagnosis. These results raise questions about using language as a clinical specifier, defining cross-sectional signs independently of their relationship with the early developmental trajectory, and relying on polythetic criteria or equivalent weighted autistic atypicalities.
LncRNA XIST promotes metastasis in ESCC by sponging miR-34a to regulate ZEB1 Expression
Authors: Guo Bin , He Ming , Ma Minting , Tian Ziqiang , Jin Jing , Tian Guo 
Published: August 2022

Abstract
Objective
LncRNA X-inactive specific transcript (XIST) is the master regulator of transcriptional silencing of X chromosome. We will study the mechanism that XIST regulates the metastasis of ESCC by regulating ZEB1.
Materials and Methods
We chose KYSE150 cell line to knock down XIST. CCK-8 was used to detect the proliferation and transwell was used to detect the migration and invasion ability. The esophageal cancer xenograft nude mouse model was established to study the effect of XIST in vivo. Luciferase reporter assays were performed to determine whether miR-34a inhibits activity of the luciferase reporter gene by binding to the predicted target sites of XIST and ZEB1. We detected the expression levels of XIST and ZEB1 in 66 paired ESCC and adjacent non-tumor tissues. Correlations between XIST and ZEB1 in tumor tissues and patient characteristics were assessed using the χ2 statistical test.
Results
Knockdown of XIST inhibits the proliferation, migration and invasion of ESCC cells. Knockdown of XIST reduced the expression level of ZEB1, and increased the expression levels of E-cadherin and miR-34a. Down-regulation the expression of miR-34a while knocking down of XIST restored the reduction in cell proliferation, migration and invasion ability caused by knocking down of XIST. The luciferase reporter assays indicated that miR-34a directly binds to the predicted target site of XIST and ZEB1. Both the expression levels of XIST (2.69 ± 1.71 VS 1.84 ± 1.67) and ZEB1 (3.24 ± 2.79 VS 1.06 ± 1.31) were significantly higher in tumor tissues than in adjacent tissues. The relative level of XIST in ESCC tissues was positive correlation with ZEB1. Overexpression of XIST and ZEB1 were associated with postoperative metastasis and shorter OS.
Conclusion
Overexpression of XIST promotes metastasis and indicates a poor prognosis in ESCC. The XIST/miR-34a/ZEB1 axis can be used as a therapeutic target and prognostic biomarker of ESCC.
Role of periosteum in alveolar bone regeneration comparing with collagen membrane in beagle dogs
Authors: Ma Zhigui , Guo Ke , Chen Lu , Chen Xinwei , Zou Duohong , Yang Chi 
Published: August 2022

Abstract
Purpose
To investigate the role of periosteum on the treatment of buccal dehiscence defects comparing with collagen membrane in canine model.
Materials and Methods
Bilateral dehiscence-type defects at the buccal side on the distal root of the lower 3rd/4th premolars were created in six beagle dogs with a total of 24 defects and assigned into 3 groups: Group A: blood clot in an untreated defect; Group B: deproteinized bovine bone material (DBBM) covered with an absorbable membrane; Group C: DBBM covered with the periosteum. The structural parameters for trabecular architecture and vertical bone regeneration were evaluated. Histological and histomorphometric evaluation were carried out to observe new bone formation and mineralization in the graft site. Immunohistochemical analysis was performed to identify the expression of osteopontin (OPN) and osteocalcin (OCN) at postoperative 3 months.
Results
Group C achieved greater vertical alveolar bone gain than that of group A and group B. The periosteum-covered group showed significantly greater new bone formation and accelerated mineralization. The greater immunolabeling for OPN and OCN was observed in group C than in group A.
Conclusions
Periosteal coverage has explicit advantages over collagen membranes for the quality and quantity of new bone regeneration in dehiscence defects repairing.
Supportive Care Needs of Breast Cancer Survivors: A Systematic Review
Authors: Khajoei Rahimeh , ZohariAnboohi Sima , Ilkhani Mahnaz 
Published: August 2022

Abstract

Purpose: In order to achieve optimal survival care outcomes, all health care services must be tailored to the patient's specific needs, preferences, and concerns through the survival period. This study aimed to identify supportive care needs from the point of view of breast cancer survivors. Methods: Following PRISMA guidelines for reporting systematic reviews, a comprehensive search of PubMed, Web of Science, and Scopus was performed. The inclusion criteria were all studies published from inception until the end of January 2022, covering all stages of breast cancer. The exclusion criteria were mixed type studies relating to cancer such as case reports, commentaries, editorials, and systematic review studies, as well as studies that assessed patients' needs during cancer treatment. Two quality assessment tools were used for the qualitative and quantitative studies under examination. Results: Of the 13,095 records retrieved, 40 studies, including 20 qualitative studies and 20 quantitative studies, were retained for this review. Survivors’ supportive care needs were classified into 11 domains. The most frequently mentioned supportive care needs of survivors were psychological/emotional needs (N=32), Health system/informational needs (N=30) physical and daily activities (N=19), and interpersonal/intimacy needs (N=19).Conclusions: This systematic review highlights a number of essential needs for breast cancer survivors. Supportive programs should be designed that consider all aspects of these needs, in particular the psychological/emotional and informational needs.
A survey on the quality of life of the elderly in rural areas --Take Donglan County, Hechi City as an example
Authors: Chen Hui , Gan Luwen , Wei Jinman , Ma Fengyi 
Published: August 2022

Abstract
Purpose of the study: To understand the influencing factors of the quality of life of the rural elderly in Hechi area, and to provide empirical evidence for improving the quality of life of the rural elderly. Methods: From December 2020 to February 2021, three natural villages were selected as survey sites in Donglan County, Hechi City, Guangxi Zhuang Autonomous Region,China by multi-stage stratified cluster random sampling,330 elderly people aged 60 and above were selected for questionnaire survey , and SPSS25.0 was used to statistic the data, and general descriptive analysis and chi-square test were used for data statistical analysis. Results: A total of 330 questionnaires were distributed in this survey, 310 valid questionnaires were returned, and 20 invalid questionnaires, and the effective questionnaire recovery rate was 94%. The results showed that factors such as educational level, occupation, health status, source of income, whether children were around, and satisfaction with health care services were statistically significant at P<0.05, which had an important impact on the quality of life of the elderly. Conclusion: Government departments should continue to increase capital investment in rural medical and health services to improve the uneven distribution of rural medical and health resources in the county;relevant departments should also strengthen the health management of the elderly in rural areas, and actively promote health education knowledge;children should pay attention to the family needs and mental health of the elderly, solve the bad emotions of the elderly in time, and listen to the life feelings and demands of the elderly. The findings can provide policy suggestions for health administrative departments to improve the quality of life of rural elderly.
Influence of Magnetic Nanoparticles and Organic Loading Rates (OLRs) on the Behavior of Continuous Stir Tank Reactor (CSTR)
Authors: Ali Asim , Mahar Rasool Bux , Panhwar Sallahuddin , Keerio Hareef Ahmed , Sherazi Tufail Hussain , Shuja Fatihah , Abdelsalam Essam M. 
Published: August 2022

Abstract
ABSTRACT
In this study, the biocompatibility of iron oxide nanoparticles (Fe3O4 NPs) with a concentration of 75 mg/L was experimentally investigated with different organic loading rates (OLRs) in Continuous Stir Tank Reactors (CSTRs). The OLRs were started from the lowest concentration of 0.3 gVS/Ld to the highest at 1.3 gVS/Ld with an intermediate of 0.8 gVS/Ld. During this experimentation, the behavior of other parameters like pH, soluble chemical oxygen demand (sCOD), total volatile fatty acids (TVFAs) generation and degradation, total solids (TS) and VS removal were monitored along with CH4 generation. It was observed that the NPs efficiency was higher at the lowest OLR. The CH4 yield was optimal at 0.3 gVS/Ld, which was 725.9 mL/gVS and reduced to 652.02 mL/gVS in R1 (with NPs additives). However, R2 (without NPs) showed much-stabilized behavior and get increasing from 372.8 to 424.4 mL/gVS at 0.3 to 1.3 gVS/Ld of OLR, respectively. Moreover, the higher removal of sCOD, TVFAs, and TV/VS were archived in R1 at the shortest hydraulic retention time (HRT).
Isometry groups of six-dimensional nilmanifolds
Authors: Ficzere Kornélia , Figula Ágota 
Published: August 2022

Abstract
We determine the 6-dimensional nilpotent metric Lie algebras such that the Lie algebra n has a descending series of ideals invariant under all automorphisms of n and the dimension of the consecutive members of the series decreases by one. We call them metric Lie algebras having a framing determined by ideals. We classify the isometry equivalence classes and determine the isometry groups of connected and simply connected Riemannian nilmanifolds on 6-dimensional nilpotent Lie groups having a Lie algebra n as their Lie algebra.Mathematics Subject Classification (2010). Primary 53C30; Secondary 57M60, 17B30, 22E25.
Participatory disease surveillance for a mass gathering - a prospective cohort study on COVID-19, Germany 2021
Authors: Hohmuth Nils , Khanyaree Ifrah , Lang Anna-Lena , Duering Ohad , Konigorski Stefan , Višković Vukašin , Heising Tobias , Egender Friedemann , Remschmidt Cornelius , Leistner Rasmus 
Published: August 2022

Abstract
Background
Mass gatherings (MGs) such as music festivals and sports events have been associated with a high risk of SARS-CoV-2 transmission. On-site research can foster knowledge of risk factors for infections and improve risk assessments and precautionary measures at future events. We tested a web-based participatory disease surveillance tool to detect COVID-19 infections at and after an outdoor mass gathering by collecting self-reported COVID-19 symptoms and tests.
Methods
We conducted a digital prospective observational cohort study among fully immunized attendees of a sports festival that took place from September 2 to 5, 2021 in Saxony-Anhalt, Germany. Participants used our study app to report demographic data, COVID-19 tests, symptoms, and their contact behavior. This self-reported data was used to define probable and confirmed COVID-19 cases during the full “study period” (08/12/2021–10/31/2021) and within the 14-day “surveillance period” during and after the event, in which the highest likelihood of an event related COVID-19 outbreak could be expected (09/04/2021–09/17/2021).
Results
A total of 2,808 of 9,242 (30.4%) event attendees participated in the study. Within the study period, 776 individual symptoms and 5,255 COVID-19 tests were reported. During the 14-day surveillance period around and after the event, seven probable and seven PCR-confirmed COVID-19 cases were detected. The confirmed cases translated to an estimated seven-day incidence of 125 per 100,000 participants (95% CI [67.7/100,000, 223/100,000]), which was comparable to the average age-matched incidence in Germany during this time. Overall, weekly numbers of COVID-19 cases were fluctuating over the study period, with another increase at the end of the study period.
Conclusion
COVID-19 cases attributable to the mass gathering were comparable to the Germany-wide age-matched incidence, implicating that our active participatory disease surveillance tool was able to detect MG-related infections. Further studies are needed to evaluate and apply our participatory disease surveillance tool in other mass gathering settings.