bluuebunny/crossref_metadata_2025_split huggingface dataset:
Information literacy: assessment of undergraduate and graduate nursing students
Authors: Allari Rabia S. , Hamdan Khaldoun , Albqoor Maha Alkaid , Shaheen Abeer 
Published: January 2022

PurposeTo describe the perceived level of information competency among nursing students in Jordan.Design/methodology/approachCross sectional-correlational design was utilized. Data were collected using an electronic self-administered questionnaire from graduate and undergraduate nursing students in Jordan.FindingsNursing students showed a moderate mean total score of information competency (184.11 out of 280, SD = 22.92). Among information competency subscales, using the information technologies subscale had the highest mean score, while information from the mass media subscale had the lowest mean score. Information competency of nursing students was positively correlated with students' age. Significant differences were found in information competency according to the academic level, addressing scientific research and research in databases in the course of the study, frequency of meeting the supervisor to discuss the research and university sector.Originality/valueAlthough there are numerous studies worldwide that assessed nursing students' information literacy, this paper represents the first study of information literacy competencies among nursing students in Jordan. While the content supports conclusions that have been drawn from other studies, this study is novel in terms of the student population it addressed. Information competency among nursing students can be improved by integrating standard research and information competency courses at the undergraduate level and involving mass media platforms in the nursing education curricula.
The impact of environmental barriers on attendance of outdoor and indoor professional sports: the case of the South Korean soccer, baseball and basketball leagues
Authors: Lee Seomgyun , Oh Taeyeon , Lim Choong Hoon 
Published: January 2022

PurposeThis study sought to determine if environmental barriers (i.e. air pollution, temperature and precipitation) affect outdoor (i.e. soccer and baseball) and indoor (i.e. basketball) professional sport attendance in South Korea.Design/methodology/approachBy including actual air quality, temperature and precipitation data collected from each place where the sporting events take place, this study conducted a regression analysis to examine factors that influenced outdoor and indoor sport attendance.FindingsIn outdoor sports, the estimated results suggested that soccer and baseball attendance were not affected by air pollution. Indoor sport consumers did not change their consumption behaviors in attending sports despite the presence of air pollution. In addition, there was mixed evidence on the effect of weather-related variables on attendance. Average temperature had a positive effect on baseball (outdoor) and basketball (indoor) sport attendance, indicating that the warmer the temperature, the more likely those fans were to attend the games. Average precipitation was negatively associated with outdoor (soccer) sport spectators.Originality/valueThe present study contributes to the sport environment literature by examining the impact of environmental barriers on spectators' behaviors in the context of outdoor and indoor professional sports.
What contributes to auditee satisfaction in external ISO 9001 audits?
Authors: Lenning Jan , Gremyr Ida , Raharjo Hendry 
Published: January 2022

PurposeThis study aims to explore factors that contribute to auditee satisfaction in external audit fieldwork of ISO 9001, and relationships between these factors.Design/methodology/approachThe purpose is addressed through a single case study and based upon data collected by a questionnaire. Data were analysed using probabilistic graphical models.FindingsAn auditor's knowledge of operations is shown to be the single most important factor contributing to auditee satisfaction in the study. Furthermore, establishing a co-operative audit atmosphere and focussing on business improvements support the co-creation of value in the interaction between auditor and auditee, while a focus on ISO compliance appears to be more of a hygiene factor.Research limitations/implicationsThis paper is based on a study of one company and its interactions with one of the certification bodies for external auditing. Hence, the generalisability of the findings is limited by the case study method.Practical implicationsThis paper identifies that an auditor's knowledge of operations and a focus on improvements and co-creation of value can improve auditee satisfaction and appreciation of the audit process.Originality/valuePrevious research has concluded that audit fieldwork is a key attribute associated with auditee satisfaction. This paper adds to this body of knowledge by empirically examining the specific factors within audit fieldwork that contribute to auditee satisfaction and focuses on value-creation in the audit process. By understanding these factors and moving towards a service perspective on audits with value co-creation as focus, it is possible to enhance the value of external audits.
Developing a pedagogical instrument for MIS fundamental course – embracing self-regulated learning strategies
Authors: Abukhader Sajed M. 
Published: January 2022

PurposeTeaching management information systems (MIS) fundamental course remains a challenging task to date, encountering several continuing complaints from students as well as instructors, as per several studies. Several reasons are reported, some of which are related to little embrace of more innovative non-traditional techniques, and limited literature guidance on selection and effective use of appropriate strategies to various settings. Toward instructional innovation, this paper proposes and tests a pedagogical instrument. By introducing this tool, the ultimate objective is to minimize the confusion that students usually encounter during this course and to empower the instructors in the delivery of its interdisciplinary knowledge.Design/methodology/approachA triangulation of four methods is being employed: conceptual development, experimentation for 12 years, assessment in light of the self-regulated learning theory, and empirical analysis. For the latter method, an open-ended questionnaire as well as group interviewing were carried out.FindingsThe proposed instrument (need-function instrument [NFI]) was found to be in support of self-regulated learning to a promising extent in terms of its four core aspects. The participants were more inclined to accept as well as appreciate the instrument than report drawbacks. Yet, there are few complaints for the inability to distinguish between two introduced terms, ‘Information Problem’ and ‘Operations Problem’. Therefore, a future effort is deemed necessary to explore this aspect.Research limitations/implicationsThe results are based on a single case of educational institution which is not enough to generalize for other educational environments. Future research is necessary for testing in a variety of settings in terms of type of classroom, number of students enrolled, type of institution (public or private), etc.Practical implicationsWhereas the instrument is anticipated to render improvements in the students’ understanding of MIS content and to alleviate the task of the course leader in delivering the course, there are possible practical implications that should be paid careful attention to. They were analyzed in terms of four dimensions: the Instructor, the Student, the Classroom and Time.Originality/valueThe paper introduces a new pedagogical instrument/tool for teaching the MIS fundamental course.
Relative contribution of high and low elevation soil microbes and nematodes to ecosystem functioning
Authors: Semeraro Sarah , Kergunteuil Alan , Sánchez‐Moreno Sara , Puissant Jérémy , Goodall Tim , Griffiths Robert , Rasmann Sergio 
Published: January 2022

Abstract

Ecosystem productivity is largely dependent on soil nutrient cycling which, in turn, is driven by decomposition rates governed by locally adapted below‐ground microbial and soil communities. How climate change will impact soil biota and the associated ecosystem functioning, however, remains largely an open question.

To address this gap, we first characterized differences in soil microbial and nematode communities as well as functional characteristics from soils collected from the foothills or in sub‐alpine elevations of the Alps. We next performed a full‐factorial reciprocal transplant common garden experiment at two elevations, and asked whether elevation‐related functional and taxonomic differences are maintained or can be altered depending on the local climatic conditions. For this, we separately transplanted soil microbial and nematode communities from low and high elevation in their home or opposite elevation in pots added with a common plant community.

We found evidence for taxonomic and functional differentiation of the microbial and nematode communities when collected at high or low elevation. Specifically, we observed a decrease in microbial diversity and activity at high elevation, and additionally, through nematodes' functional characterization, we found increased fungal‐dominated energy channels at high elevation.

Moreover, according to the reciprocal transplant experiment, while we found little effect of soil biodiversity change based on elevation of origin on plant growth and plant community composition, soils inoculated with microbes originating from low elevation respired more than those originating from high elevation, particularly when at low elevation. This observation correlates well with the observed faster carbon degradation rates by the low elevation microbial communities.

Climate change can reshuffle soil communities depending on organism‐specific variation in range expansion, ultimately affecting soil fertility and carbon‐cycle dynamics.

A free Plain Language Summary can be found within the Supporting Information of this article.
Blood filters in children with COVID‐19 and acute kidney injury: A review
Authors: Raina Rupesh , Sethi Sidharth Kumar , Chakraborty Ronith , Singh Siddhartha , Teo Sharon , Khooblall Amrit , Montini Giovanni , Bunchman Timothy , Topaloglu Rezan , Yap Hui Kim 
Published: January 2022

AbstractCOVID‐19 has challenged the global healthcare system through rapid proliferation and lack of existing treatment resulting in over 180 million cases and 3.8 million deaths since December 2019. Although pediatric patients only comprise 1%–2% of diagnosed cases, their incidence of acute kidney injury ranges from 8.2% to 18.2% compared to 49% in adults. Severe infection, initiated by dysregulated host response, can lead to multiorgan failure. In this review, we focus on the use of various blood filters approved for use in pediatric kidney replacement therapy to mitigate adverse effects of severe illness. Therapeutic effects of these blood filters range from cytokine removal (CytoSorb, HA330, HCO/MCO), endotoxin removal (Toraymyxin, CPFA), both cytokine and endotoxin removal (oXiris), and nonspecific removal of proteins (PMMA) that have already been established and can be used to mitigate the various effects of the cytokine storm syndrome in COVID‐19.
Adverse effects of iron toward the peritoneal mesothelial cells are reversible
Authors: Jasiński Tomasz , Bręborowicz Andrzej 
Published: January 2022

AbstractIntroductionEvaluation of the effects of the drugs used for iron supplementation on the peritoneal mesothelial cells.MethodsAcute effects during18‐h incubation of iron sucrose, ferric carboxymaltose, and iron isomaltoside in concentrations 1, 5, and 20 ug/dl on properties of the human peritoneal mesothelial cells in in vitro culture were evaluated, and their reversibility after the following culture for 14 days in the iron‐free medium was studied.ResultsAll studied compounds reduced viability of mesothelial cells and proliferation rate and increased intracellular oxidative stress and iron content in the cytosol. Secretion of monocyte chemoattractant protein‐1 was increased and tissue plasminogen activator (t‐PA) decreased. After 14 days of culture in iron‐free medium, reversibility of all these effects was observed.ConclusionIron compounds impair the functional properties of mesothelial cells in a dose‐dependent manner, but these effects are reversible after the following culture of the cells in an iron‐free medium.
The American racial divide in fear of the police
Authors: Pickett Justin T. , Graham Amanda , Cullen Francis T. 
Published: January 2022

AbstractThe mission of policing is “to protect and serve,” but recent events suggest that many Americans, and especially Black Americans, do not feel protected from the police. Understanding police‐related fear is important because it may impact civilians’ health, daily lives, and policy attitudes. To examine the prevalence, sources, and consequences of both personal and altruistic fear of the police, we surveyed a nationwide sample (N = 1,150), which included comparable numbers of Black (N = 517) and White (N = 492) respondents. Most White respondents felt safe, but most Black respondents lived in fear of the police killing them and hurting their family members. Approximately half of Black respondents preferred to be robbed or burglarized than to have unprovoked contact with officers. The racial divide in fear was mediated by past experiences with police mistreatment. In turn, fear mediated the effects of race and past mistreatment on support for defunding the police and intentions to have “the talk” with family youths about the need to distrust and avoid officers. The deep American racial divide in police‐related fear represents a racially disparate health crisis and a primary obstacle to law enforcement's capacity to serve all communities equitably.
Marketization and crime in contemporary China: Puzzles for criminological theorizing*
Authors: Messner Steven F. 
Published: January 2022

AbstractThe purpose of my Sutherland Address is to explore the potential utility of elaborating and adapting the analytic framework of Institutional Anomie Theory (IAT) to account for the macro‐social dynamics of crime in contemporary China. To do so, I situate the institutional dynamics of crime in China in comparative historical context and put forth a newly adapted formulation of IAT. I then illustrate the ways in which this adapted formulation of IAT can enhance the coherence of a rich body of research on crime in China by incorporating some of the empirical findings and insightful interpretations within an overarching theoretical framework. In addition, interrogating the applicability of IAT to the Chinese context draws attention to important gaps in the theory, thereby facilitating its further elaboration as well as promoting the development of general macro‐social theory in criminology.
Styles of Regulators: Evidence from the SEC's Comment Letters†
Authors: Do Truc (Peter) Thuc , Zhang Huai 
Published: January 2022

ABSTRACTWe investigate whether individual securities regulators exhibit personal styles in their work, a question of importance to corporate executives and capital market participants. Using the SEC's comment letters as our setting, we find that SEC staff members exhibit unique personal “styles.” We manually collect information on SEC staff members and provide evidence that staff members' personal characteristics influence the SEC's review process. Further analyses reveal that SEC staff members with a CPA qualification are associated with a lower likelihood of future accounting restatements; moreover, similarity between the SEC staff member and the firm's correspondent is associated with lower scrutiny intensity. Overall, our study offers evidence that SEC staff members exhibit individual differences and that their styles shape the SEC's enforcement actions. Our results offer implications for the working of securities regulators.
Allergen immunotherapy and/or biologicals for IgE‐mediated food allergy: A systematic review and meta‐analysis
Authors: de Silva Debra , Rodríguez del Río Pablo , de Jong Nicolette W. , Khaleva Ekaterina , Singh Chris , Nowak‐Wegrzyn Anna , Muraro Antonella , Begin Philippe , Pajno Giovanni , Fiocchi Alessandro , Sanchez Angel , Jones Carla , Nilsson Caroline , Bindslev‐Jensen Carsten , Wong Gary , Sampson Hugh , Beyer Kirsten , Marchisotto Mary‐Jane , Fernandez Rivas Montserrat , Meyer Rosan , Lau Susanne , Nurmatov Ulugbek , Roberts Graham ,   the GALEN Food Allergy Guidelines Group
Published: January 2022

AbstractBackgroundThere is substantial interest in immunotherapy and biologicals in IgE‐mediated food allergy.MethodsWe searched six databases for randomized controlled trials about immunotherapy alone or with biologicals (to April 2021) or biological monotherapy (to September 2021) in food allergy confirmed by oral food challenge. We pooled the data using random‐effects meta‐analysis.ResultsWe included 36 trials about immunotherapy with 2126 mainly child participants. Oral immunotherapy increased tolerance whilst on therapy for peanut (RR 9.9, 95% CI 4.5.–21.4, high certainty); cow's milk (RR 5.7, 1.9–16.7, moderate certainty) and hen's egg allergy (RR 8.9, 4.4–18, moderate certainty). The number needed to treat to increase tolerance to a single dose of 300 mg or 1000 mg peanut protein was 2.Oral immunotherapy did not increase adverse reactions (RR 1.1, 1.0–1.2, low certainty) or severe reactions in peanut allergy (RR 1,6, 0.7–3.5, low certainty), but may increase (mild) adverse reactions in cow's milk (RR 3.9, 2.1–7.5, low certainty) and hen's egg allergy (RR 7.0, 2.4–19.8, moderate certainty). Epicutaneous immunotherapy increased tolerance whilst on therapy for peanut (RR 2.6, 1.8–3.8, moderate certainty). Results were unclear for other allergies and administration routes.There were too few trials of biologicals alone (3) or with immunotherapy (1) to draw conclusions.ConclusionsOral immunotherapy improves tolerance whilst on therapy and is probably safe in peanut, cow's milk and hen's egg allergy. More research is needed about quality of life, cost and biologicals.
Cashew oral immunotherapy for desensitizing cashew‐pistachio allergy (NUT CRACKER study)
Authors: Elizur Arnon , Appel Michael Y. , Nachshon Liat , Levy Michael B. , Epstein‐Rigbi Naama , Koren Yael , Holmqvist Marie , Porsch Helena , Lidholm Jonas , Goldberg Michael R. 
Published: January 2022

AbstractBackgroundOral immunotherapy (OIT) is a treatment option for patients with milk, egg, and peanut allergy, but data on the efficacy and safety of cashew OIT are limited.MethodsA cohort of 50 cashew‐allergic patients aged ≥4 years, who were consecutively enrolled into cashew OIT (target dose 4000 mg protein) between 4/2016 and 12/2019. Fifteen cashew‐allergic patients who continued cashew elimination served as observational controls. Co‐allergy to pistachio and walnut was determined. Full desensitization rate and associated immunological changes in both groups were compared. Patients fully desensitized to cashew were instructed to consume a dose of 1200 mg cashew protein for 6 months and were then challenged to a full dose. Patients with co‐allergy to pistachio or walnut were challenged to the respective nut.ResultsForty‐four of 50 OIT‐treated patients (88%) compared to 0% in controls tolerated a dose of 4000 mg cashew protein at the end of the study (odds ratio 8.3, 95% CI 3.9–17.7, p < 0.001). An additional three patients were desensitized to 1200 mg cashew protein, and three patients stopped treatment. Three patients (6%) were treated with injectable epinephrine for home reactions. Desensitized patients had decreased SPT, sIgE, basophil reactivity, and increased sIgG4, following treatment. Following cashew desensitization, all pistachio (n = 35) and four of eight walnut co‐allergic patients were cross‐desensitized to the respective nut. All (n = 44) patients consuming a low cashew dose for ≥6 months following desensitization passed a full‐dose cashew OFC.ConclusionsCashew OIT desensitizes most cashew‐allergic patients and cross‐desensitizes to pistachio. Safety is similar to OIT for other foods.
Sensitivity of estimated tacrolimus population pharmacokinetic profile to assumed dose timing and absorption in real‐world data and simulated data
Authors: Williams Michael L. , Weeks Hannah L. , Beck Cole , Birdwell Kelly A. , Van Driest Sara L. , Choi Leena 
Published: January 2022

AimsUse of electronic health record (EHR) data to estimate population pharmacokinetic (PK) profiles necessitates several assumptions. We sought to investigate sensitivity to some of these assumptions about dose timing and absorption rates.MethodsA population PK study with 363 subjects was performed using real‐world data extracted from EHRs to estimate the tacrolimus population PK profile. Data were extracted and built using our automated system, EHR2PKPD, suitable for quickly constructing large PK datasets from the EHR. Population PK studies for oral medications performed using EHR data often assume a regular dosing schedule as prescribed without incorporating exact dosing time. We assessed the sensitivity of the PK parameter estimates to assumptions about dose timing using last‐dose times extracted by our own natural language processing system, medExtractR. We also investigated the sensitivity of estimates to absorption rate constants that are often fixed at a published value in tacrolimus population PK analyses. We conducted simulation studies to investigate how drug PK profiles and experimental designs such as concentration measurements design affect sensitivity to incorrect assumptions about dose timing and absorption rates.ResultsThere was no appreciable difference in parameter estimates with assumed versus extracted last‐dose time, and our sensitivity analysis revealed little difference between parameters estimated across a range of assumed absorption rate constants.ConclusionOur findings suggest that drugs with a slower elimination rate (or a longer half‐life) are less sensitive to dose timing errors and that experimental designs which only allow for trough blood concentrations are usually insensitive to deviation in absorption rate.
Bayesian Inference for Stationary Points in Gaussian Process Regression Models for Event-Related Potentials Analysis
Authors: Yu Cheng-Han , Li Meng , Noe Colin , Fischer-Baum Simon , Vannucci Marina 
Published: January 2022

Abstract
Stationary points embedded in the derivatives are often critical for a model to be interpretable and may be considered as key features of interest in many applications. We propose a semiparametric Bayesian model to efficiently infer the locations of stationary points of a nonparametric function, which also produces an estimate of the function. We use Gaussian processes as a flexible prior for the underlying function and impose derivative constraints to control the function's shape via conditioning. We develop an inferential strategy that intentionally restricts estimation to the case of at least one stationary point, bypassing possible mis-specifications in the number of stationary points and avoiding the varying dimension problem that often brings in computational complexity. We illustrate the proposed methods using simulations and then apply the method to the estimation of event-related potentials derived from electroencephalography (EEG) signals. We show how the proposed method automatically identifies characteristic components and their latencies at the individual level, which avoids the excessive averaging across subjects that is routinely done in the field to obtain smooth curves. By applying this approach to EEG data collected from younger and older adults during a speech perception task, we are able to demonstrate how the time course of speech perception processes changes with age.