bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of Risk Factors for Rupture in Breast Reconstruction Patients with Macrotextured Breast Implants
Authors: Paolini Guido , Firmani Guido , Briganti Francesca , Macino Mattia , Nigrelli Simone , Sorotos Michail , Santanelli di Pompeo Fabio 
Published: October 2022

Abstract
Background
Breast implants (BI) are widely used in plastic surgery, though they are not lifetime devices. Average life before rupture is reported to be around 10–15 years. No consensus exists regarding which factors are involved.

Objectives
Following FDA recommendations, this study aims at identifying potential risk factors by evaluating their effect on BI rupture cases.

Methods
In this observational study, 763 BI patients were operated between 2003 and 2019, with a mean implant indwelling of 12.2 years. Patients that returned for follow-up were administered a questionnaire regarding postoperative lifestyle and habits. Implant rupture rate was 15.1%, while BI lifespan was 10.1 years. We obtained complete data from 191 breast implant patients (288 implants). Twenty-three potential risk factors were evaluated and divided in four categories: patient-related, surgery-related, postoperative complications/symptoms, and postoperative care/lifestyle habits. Odds Ratio (OR) for each factor was calculated. Linear regression analysis was calculated for those with a significant OR.

Results
We report 120 patients (195 implants) with intact and 71 (93 implants) with ruptured devices. BIs were macrotextured in 95.1% of cases (86.8% Allergan BIOCELL). OR was significant for underwire bra use (OR: 2.708), car seat belts (OR: 3.066), mammographic imaging (OR: 2.196), weightlifting (OR: 0.407) and carry-on heavy purses and backpacks (OR: 0.347).

Conclusion
Wearing underwire bras, seat belts and undergoing mammography increases the risk of rupture. Weightlifting and carry heavy bags do not increase that risk. Implant rupture is directly linked with time of indwelling. Postoperative recommendations in BI patients should consider findings from our study, though larger multicenter studies should be encouraged.

Level of Evidence IV
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
Fusion seismischer, akustischer und optischer Unterwasserdaten und Modelle zur Analyse submariner Hangrutschungen an Vulkansystemen
Authors: Köser K. , Kwasnitschka T. , Urlaub M. 
Published: October 2022

ZusammenfassungDie Messung submariner Bodendeformationen an den Flanken von Inselvulkanen hilft dabei, ihre Stabilität und die Gefahr von Hangrutschungen einzuschätzen, ist aber inherent schwierig für Gebiete, die unter Wasser liegen. Wiederholte Seismik- oder Fächerecholot-Vermessungen können größere Gebiete abdecken, aber Auflösung und Lokalisierung sind bestimmten Grenzen unterworfen. Optische Daten andererseits sind besser aufgelöst, aber limitiert in ihrer räumlichen Abdeckung, und Meeresbodengeodäsie wiederum liefert nur punktuelle Information. In diesem Artikel schlagen wir vor, verschiedene Arten von Fernerkundungsdaten zusammenzubringen und auch mit bestehenden statischen und dynamischen Modellen zu verschneiden. Aufgrund ihrer verschiedenen Modalitäten, Unsicherheiten und Skalierungen ist dies jedoch schwierig und bedarf einer Fusion. Zusammen mit anderen Aspekten (Erdbeben, Strömungen etc.) sollen die fusionierten Daten und Modelle langfristig neue Einblicke in das dynamische System des sich verändernden Meeresbodens, die dafür verantwortlichen Faktoren sowie die Auswirkungen instabiler submariner Hänge auf andere Meeressysteme bieten.
Acute response of biomarkers in plasma from capillary blood after a strenuous endurance exercise bout
Authors: Reichel Thomas , Held Steffen , Schwarz Anthony , Hacker Sebastian , Wesemann Fabian , Donath Lars , Krüger Karsten 
Published: October 2022

Abstract
Purpose
The present study aims to investigate the acute response of potential exercise-sensitive biomarkers in capillary plasma to an acute incremental running test. In a second step, their concentration was compared to the changes in the venous serum.

Methods
Thirty-seven active young female and male adults completed a VO2max ramp test on a treadmill. Before and after exercise, capillary blood from the earlobe and venous blood were taken and synchronized. Concentrations of Interleukin- (IL-) 1β, IL-1ra, IL-6, IL-8, IL-17A, Interferon (IFN)-y, CC-chemokine ligand (CCL)-2, Matrix metallopeptidase (MMP)-9, Secreted protein acidic and rich in cysteine (SPARC), Cluster of differentiation (CD)163, S100 Ca2+ -binding protein (S100) A8, S100A9, S100B, Brain-derived neurotrophic factor (BDNF), and Myeloperoxidase (MPO) were determined by magnetic bead-based multiplex assay.

Results
Capillary plasma concentrations of IL-1β, IL-6, IL-8, IL-17A, IFN-y, CCL-2, MMP-9, SPARC, CD163, S100A9, S100B, and BDNF increased after exercise (p < 0.05). Comparing the values from capillary plasma and venous serum, ICCs classified as good were found for IFN-y (post), while the ICCs for IL-1β, IL-8, IL-17A, CCL-2, MMP-9 (post), SPARC, and BDNF (post) were classified as moderate. For all other parameters, only weak ICCs were found.

Conclusion
As in the venous serum, there was an increase in most markers in the capillary plasma. However, acceptable to low associations can be found in the concentration levels of these proteins between the compartments. Thus, this source of blood sampling could find some biomarker applications in sports practice.
Time course of adverse reactions following BNT162b2 vaccination in healthy and allergic disease individuals aged 5–11 years and comparison with individuals aged 12–15 years: an observational and historical cohort study
Authors: Yoshida Makoto , Kobashi Yurie , Shimazu Yuzo , Saito Hiroaki , Yamamoto Chika , Kawamura Takeshi , Wakui Masatoshi , Takahashi Kenzo , Ito Naomi , Nishikawa Yoshitaka , Zhao Tianchen , Tsubokura Masaharu 
Published: October 2022

AbstractWe aimed to investigate the type and frequency of adverse events over 7 days following the first and second BNT162b2 vaccination. This observational and historical cohort study included patients aged 5–11 years who received two doses of BNT162b2 and provided consent along with their guardians. We collected data on sex, age, height, weight, blood type, history of Bacille Calmette-Guerin vaccination, allergic disease, medication, history of coronavirus disease 2019 (COVID-19), and adverse reactions 7 days following the first and second BNT162b2 vaccination using a questionnaire. Our results were compared with previously reported results for individuals aged 12–15 years. A total of 421 participants were eligible for this study. Among the 216 patients with allergic disease, 48 (22.2%) had experienced worsening of their chronic diseases, and the frequency of fatigue and dizziness after the second dose was higher than that of healthy individuals. The experience of systemic adverse reactions was associated with asthma. The frequency of headache, diarrhea, fatigue, muscle/joint pain, and fever after the second BNT162b2 vaccination was lower in individuals aged 5–11 years than in those aged 12–15 years. Fever was the only systemic adverse reaction that lasted longer than 5 days (1.0% of participants).Conclusions: Individuals with allergic diseases, who are potentially susceptible to COVID-19, may experience worsening of their chronic diseases and more frequent adverse reactions after BNT162b2 vaccination than healthy individuals. To ensure that children with allergic diseases receive the vaccine safely, further information needs to be collected.

What is Known:• Adverse reactions after
BNT162b2 vaccination among individuals aged 5–11 years are generally
nonserious, more common after second vaccination, and substantially less common
compared to those observed among individuals aged 12–15 years.

What is New:• Individuals with allergic diseases
experienced worsening of their chronic diseases and more frequent adverse
reactions after BNT162b2 vaccination than healthy individuals.• Systemic adverse reactions were associated
with asthma. Fever was the only systemic adverse
reaction that lasted longer than 5 days.
Genotype and phenotype analysis and transplantation strategy in children with kidney failure caused by NPHP
Authors: Li Jianyi , Su Xiaojun , Zhang Huanxi , Wu Wenrui , Li Jianming , Chen Yanxu , Li Jun , Fu Qian , Wu Chenglin , Zhong Xuhui , Wang Changxi , Liu Longshan 
Published: October 2022

Abstract

Background
Nephronophthisis-related ciliopathies (NPHP-RC) have strong genotype and phenotype heterogeneity, and the transplantation strategy of Boichis syndrome is still controversial. Our purpose was to examine associations of genotype and phenotype in children with NPHP-RC and analyze the transplantation strategies of different phenotypes.

Methods
The records of children with NPHP treated at our center from 01/2018 to 03/2021 were retrospectively reviewed. Inclusion criteria were a diagnosis of NPHP, received kidney transplantation, and received whole exome sequencing (WES) or nephropathy gene panel testing.

Results
Twenty-nine children with NPHP were included. Nine children (31%) had NPHP1 mutations, and all presented with isolated nephropathy. Eighteen of 20 patients with non-NPHP1 mutations had compound heterozygous mutations, and 70% had extrarenal phenotype. Age at disease presentation (11.2 ± 1.94 years) and the development of kidney failure (12.4 ± 2.70 years) were later in children with NPHP1 mutations than those with non-NPHP1 mutations (5.2 ± 2.83 years and 5.7 ± 2.92 years, respectively). Four of six children with NPHP3 mutations were diagnosed with Boichis syndrome due to liver fibrosis. Isolated kidney transplantation resulted in good outcomes for patients with mild or moderate liver fibrosis without portal hypertension, while cholestasis was common postoperatively and could be resolved with ursodeoxycholic acid.

Conclusions
NPHP1 mutations are the most common in children with NPHP, and the phenotype of NPHP1 mutation is significantly different from that of non-NPHP1 mutation. For NPHP patients with mild to moderate liver fibrosis without portal hypertension, timely treatment of cholestasis could prevent the rapid progression of liver function damage after isolated kidney transplantation.

Graphical abstract
Space weather phenomena on heart rate: a study in the Greek region
Authors: Papailiou Maria , Ioannidou Sofia , Tezari Anastasia , Lingri Dimitra , Konstantaki Maria , Mavromichalaki Helen , Dimitrova Svetla 
Published: October 2022

Abstract
Many scientific investigations have focused on how space weather phenomena, taking place in the vicinity of the Earth, may influence different aspects of life on Earth and presumably human health itself. From 2005, the National and Kapodistrian University of Athens has established an important position in the field of these investigations by collaborating with various scientists and Institutes, both international and domestic, in different heliobiological projects. In this work, the Cosmic Ray Group of the National and Kapodistrian University of Athens has co-operated with the medical staff from different hospitals and clinics around the country so as to develop large records of medical data (heart rate) which covers a long time period. These data are analyzed in regard to physical activity, either on a daily basis or on different levels of geomagnetic disturbances and variations of the cosmic ray intensity using the ANalysis Of Variance (ANOVA) and the multiple linear regression analysis. Results suggest that space weather phenomena may be related to heart rate variability, i.e., heart rate is statistically significantly effected either by variations of cosmic rays intensity or geomagnetic activity.
Investigating a citrus fruit supply chain network considering CO2 emissions using meta-heuristic algorithms
Authors: Goodarzian Fariba , Kumar Vikas , Ghasemi Peiman 
Published: October 2022

AbstractAccording to the increasing carbon dioxide released through vehicles and the shortage of water resources, decision-makers decided to combine the environmental and economic effects in the Agri-Food Supply Chain Network (AFSCN) in developing countries. This paper focuses on the citrus fruit supply chain network. The novelty of this study is the proposal of a mathematical model for a three-echelon AFSCN considering simultaneously CO2 emissions, coefficient water, and time window. Additionally, a bi-objective mixed-integer non-linear programming is formulated for production–distribution-inventory-allocation problem. The model seeks to minimise the total cost and CO+ emission simultaneously. To solve the multi-objective model in this paper, the Augmented Epsilon-constraint method is utilised for small- and medium-sized problems. The Augmented Epsilon-constraint method is not able to solve large-scale problems due to its high computational time. This method is a well-known approach to dealing with multi-objective problems. It allows for producing a set of Pareto solutions for multi-objective problems. Multi-Objective Ant Colony Optimisation, fast Pareto genetic algorithm, non-dominated sorting genetic algorithm II, and multi-objective simulated annealing are used to solve the model. Then, a hybrid meta-heuristic algorithm called Hybrid multi-objective Ant Colony Optimisation with multi-objective Simulated Annealing (HACO-SA) is developed to solve the model. In the HACO-SA algorithm, an initial temperature and temperature reduction rate is utilised to ensure a faster convergence rate and to optimise the ability of exploitation and exploration as input data of the SA algorithm. The computational results show the superiority of the Augmented Epsilon-constraint method in small-sized problems, while HACO-SA indicates that is better than the suggested original algorithms in the medium- and large-sized problems.
Twin-roll forming, a novel method for producing high-consistency microfibrillated cellulosic films
Authors: Sharifi Zamani Elaheh , Ahadian Hamidreza , Maloney Thaddeus 
Published: October 2022

AbstractMicro-nano fibrillated cellulose (MNFC) films have the potential for applications in, e.g., packaging and printed electronics. However, the production paradigm for these types of products has still not been established. This study uses twin-rollers to form films from high consistency (15% w/w) micro fibrillated cellulose furnishes. MFC furnishes were produced at 20% wt dry matter content with enzymatic hydrolysis and PFI refining. We used the twin-roller method to spread the material over a supporting substrate by repeatedly passing between two parallel rollers with decreasing nip. Rheological behavior and physical properties of furnishes were analyzed. We found that only some furnishes with relatively short fiber lengths were formable. Refining improved the formation of the sheets. Roll-formed sheets showed comparable strength and formation to conventional wet-laid hand sheets.
The impact of varying doses of moringa leaf methanolic extract supplementation in the cryopreservation media on sperm quality, oxidants, and antioxidant capacity of frozen-thawed ram sperm
Authors: El-Seadawy Islam E. , Kotp Mohamed S. , El-Maaty Amal M. Abo , Fadl Aya M. , El-Sherbiny Hossam R. , Abdelnaby Elshymaa A. 
Published: October 2022

Abstract
To increase rams’ post-thaw semen quality following cryopreservation, this study used enriched Tris-based diluent with varying amounts of moringa leaf methanolic extract (MLME). The antioxidant activity, total phenolic, and total flavonoid content were all assessed in MLME. The sperm of five healthy Awassi rams were collected, divided into 4 equal aliquots, and diluted [1:5; (v/v)] in Tris-citrate-glucose extender supplemented with 0.48, 0.56, and 0.64 mg MLME/ml or without MLME supplementation (control). The percentages of sperm total motility (STM, %), sperm progressive motility (SPM, %) and viability (V, %), abnormal morphology (AM, %), membrane functional integrity (MFI, %), and acrosome integrity (AI %) were measured. Malondialdehyde (MDA), nitric oxide (NO), ascorbic acid (AA), superoxide dismutase (SOD), glutathione peroxidase (GPx), total cholesterol (TC), low-density lipoproteins (LDL), lactate dehydrogenase (LDH), alkaline phosphatase (ALP), zinc (Zn), and copper (Cu) were measured. The total phenolic gallic acid and flavonoid catechin (equivalent) contents were 19.78 mg/g and 11.94 mg/g, respectively. 2,2-Diphenyl-1-picrylhydrazyl (34.37 mM TE/g) and 2,2′-azino-bis/3-ethylbenzothiazoline-6-sulfonic acid (53.47 mM TE/g) were found in MLME. MLME had a 64.59 mM TE/g ferric-reducing power. In comparison to control, the addition of 0.64 mg/ml MLME to Tris-based extender resulted in the highest (P < 0.001) STM (55.22 ± 0.98), SPM (45.41 ± .70), SV (60.01 ± 1.05), MFI (75.23 ± 0.77), and AI (73.13 ± 0.72) and the lowest (P < 0.001) AM (21.34 ± 0.72) values. In comparison to the control, the addition of 0.56 mg/ml semen extender resulted in lower STM, SPM, SV, MFI, and AI with higher AM percentages. MDA (P = 0.03), NO (P = 0.012), CHO (P = 0.0001), and LDL (P = 0.004) were reduced by 0.64 mg/ml MLME, while AA (P = 0.017) and SOD (P = 0.0001) were elevated. In conclusion, the highest copper (P = 0.006) and lowest zinc concentrations in MLME (0.48 mg/ml extender) deteriorated the post-thaw semen quality, prompting us to suggest the addition of 0.64 mg MLME to rams’ Tris-based semen extender.
Humor as a Multifaceted Resource in Healthcare: An Initial Qualitative Analysis of Perceived Functions and Conditions of Medical Assistants’ Use of Humor in their Everyday Work and Education
Authors: Raecke Julia , Proyer René T. 
Published: October 2022

AbstractIt has been argued that humor serves as a crucial resource for healthcare professionals (HCPs). For example, they can use it to cope with work stress, to build relationships with patients, and/or to educate medical students and residents—to name but a few functions. However, empirical studies on the importance of humor among HCPs are still scarce. Existing studies primarily focus on nurses and physicians and rarely distinguish between different humor styles (e.g., light and dark). Based on qualitative interviews with 14 German Medical Assistants (MAs), we investigate the potential of humor as a resource for MAs’ work and education. We focus on the perceived functions and conditions of MAs’ successful use of humor as well as the role of humor styles (i.e., comic styles). Results indicate various functions of humor in MAs’ everyday work (e.g., soothing patients, coping with mistakes, fostering team cohesion, or promoting apprentices’ education) as well as different conditions for a successful use of humor (e.g., positive social basis, current well-being, and social sensitivity). Further, the results suggest that the use of a certain humor style depends on the interlocutor as well as the intended goal of the humor. The results not only stress the multifaceted potential as well as the relevance of conditions of successful humor for MAs’ everyday work and education, but also provide valuable real-life insights into MAs’ everyday humor, thus offering several implications for practice to promote humor as a positive resource in MAs.
Advanced Fiber Materials for Wearable Electronics
Authors: Zhu Chuang , Wu Jiawei , Yan Jianhua , Liu Xuqing 
Published: October 2022

AbstractFiber materials are highly desirable for wearable electronics that are expected to be flexible and stretchable. Compared with rigid and planar electronic devices, fiber-based wearable electronics provide significant advantages in terms of flexibility, stretchability and breathability, and they are considered as the pioneers in the new generation of soft wearables. The convergence of textile science, electronic engineering and nanotechnology has made it feasible to build electronic functions on fibers and maintain them during wear. Over the last few years, fiber-shaped wearable electronics with desired designability and integration features have been intensively explored and developed. As an indispensable part and cornerstone of flexible wearable devices, fibers are of great significance. Herein, the research progress of advanced fiber materials is reviewed, which mainly includes various material preparations, fabrication technologies and representative studies on different wearable applications. Finally, key challenges and future directions of fiber materials and wearable electronics are examined along with an analysis of possible solutions.
Graphical abstract
Low velocity perforation of thick magnesium alloy AM60 plates impacted by rigid conical-nose impactor
Authors: Nowak Zdzisław , Kowalewski Zbigniew L. , Szymczak Tadeusz 
Published: October 2022

Abstract
The impact resistance behaviour of the plate made of the AM60 magnesium alloy at the low velocity impact perforation mode is here investigated at room temperature using a numerical approach based on experimental results. Dynamic tests were performed using an impact digital tower on the 10.0 mm thick AM60 magnesium alloy plates using cylindrical impactors with conical-nose shapes of a nominal diameter of 12.0 mm, and a nominal mass of 5.77 kg. The plates were impacted with velocities ranging from 7 to 16 m/s. During the experiments, the failure of the target plates was evaluated. Finite element (FE) model was validated using experimental results. FE simulations of the conducted experiments were performed with ABAQUS software. In simulations the strain rate dependent Johnson–Cook yield criterion with a strain hardening law was accompanied with either the ductile fracture criterion or stress triaxiality-dependent JC fracture criterion to describe the target material properties. The stress and strain distributions for different impactor velocity considered were calculated using initial impact velocity data obtained from the experiments. A range of parameters, like element size, the fracture initiation strain, friction coefficient, etc. which play an important role in the simulation, were studied. The results of numerical simulation were compared with those from the experiment obtained. A good agreement between them was achieved. The failure process of AM60 target-plate revealed that in the case of the conical-nose impactor, the ductile hole enlargement occurs during the initial stage of the impact, and subsequently, a through-thickness fracture develops causing its shear plugging failure.