bluuebunny/crossref_metadata_2025_split huggingface dataset:
Екологiя людського суспiльства
Authors: Н. Тимофеєва Бесіду вела 
Published: July 2022

Станiслав Васильович Адаменко — iнженер-фiзик, науковий керiвник Лабораторiї електродинамiчних дослiджень «Протон 21» (Київ). Вiн брав активну участь у становленнi нашого журналу. У перших випусках видання була публiкована низка його праць.У 2012 роцi Станiслав Адаменко дав iнтерв’ю журналу, яке не було опублiковане. Прiоритет тодi вiддавався езпосередньо статтям самого автора. У цьому випуску ми публiкуємо фрагмент згаданого iнтерв’ю: сьогоднi воно є не менш актуальним, анiж десять рокiв тому.У другому номерi «Вiсника Нацiональної академiї наук України» вiд 2003 року була опублiкована стаття С.В. Адаменка, у якiй йшлося про вiдкриття методу «несилового», або «холодного», контрольованого ядерного синтезу. У передмовi до статтi автор писав: «Серед актуальних проблем сучасної науки керована трансмутацiя елементiв та iзотопiв належить до найпрiоритетнiших. Вона є ключовою для розв’язання таких нагальних питань, як екологiчно безпечне використання ядерної енергiї, технологiчний синтез малопоширених iзотопiв, безпечна та ефективна переробка й утилiзацiя радiоактивних вiдходiв, синтез надважких трансуранових ядер. Кожне з цих питань протягом десятилiть намагаються вирiшити великi науковi центри iндустрiально розвинених країн iз залученням найквалiфiкованiших фахiвцiв та великих фiнансових i технiчних ресурсiв. Однак досягти iстотних результатiв, якi можна було б широко впровадити у практику, поки що не вдається.Втiм змiна концептуальних пiдходiв дала змогу одержати дуже обнадiйливi експериментальнi результати». Експерименти, проведенi у Лабораторiї «Протон 21», показали, що визначений вплив когерентного електричного струму на металеву мiшень призводить до внутрiшнього ядерного збудження мiшенi та її вибуху В результатi вiдбувається перетворення ядер металу мiшенi на ядра синтезованих iзотопiв. При цьому енергiя когерентного драйвера, який генерує такий процес, має лише малу частку вiд енергiї, яка видiляється у результатi ядерногосинтезу. У випадку створення промислової установки, яка буде використовувати такий метод, можливе вирiшення задачi забезпечення енергоресурсами у свiтовому масштабi.
A semântica do pretérito imperfeito do indicativo com o verbo querer em português: modalidade e evidencialidade
Authors: De Paula Bruno Alves 
Published: July 2022

Este artigo pretende analisar a semântica do Pretérito Imperfeito do Indicativo, com o verbo querer, do ponto de vista da modalidade e da evidencialidade. Trata-se, mais concretamente, de casos em que essa forma verbal deixa de expressar o seu valor básico, temporal, para sinalizar um valor secundário, de cariz modal, sendo essas ocorrências de Imperfeito com leitura modal normalmente identificadas pela literatura linguística como um mesmo caso de “Imperfeito de Cortesia”. Buscar-se-á demonstrar que, a depender da evidência na base de uma enunciação com o verbo querer flexionado no Pretérito Imperfeito do Indicativo, haverá um ou outro posicionamento avaliativo do enunciador, sugerindo a existência de valores modais distintos, assinalados através da forma verbal em questão.
Interfaces do não desenvolvimento da maternidade na revista Pais & Filhos (1969-1972)
Authors: Martins Thayná Guedes Assunção , Marinho Joseanne Zingleara Soares 
Published: July 2022

A maternidade, sobretudo ao longo do século XX, foi uma condição sobre a qual foram realizadas fortes investidas sociais a partir das mentes e corpos femininos. Aquelas que se encontravam distantes do modelo de mulher pautado pelo matrimônio, maternidade e dedicação ao lar, eram incorporadas ao campo do diferente, inviabilizado e, muitas vezes, do patológico. Contudo, ao se aproximar do século XXI foi se tornando cada vez mais insustentável manter essas mulheres no campo do não visto. Dessa forma, este estudo se propõe a analisar as representações sobre o não exercício da maternidade a partir das reportagens da revista Pais & Filhos, um periódico de circulação nacional que tinha como foco leitor as mulheres mães, sob o recorte temporal de 1969 a 1972. A análise enfoca a visão incorporada pelo periódico no que tange ao não desenvolvimento da atividade maternal, abordando aspectos variados dessa condição, como a questão da relação com o trabalho e a saúde a partir de temáticas sobre o aborto e a contracepção, assuntos que se entrelaçam no cerne da condição não materna.
Palavras-chave: História. Gênero. Não maternidade. Revista Pais & Filhos.
Minimally invasive lateral retroperitoneal transpsoas approach for lumbar corpectomy and fusion with posterior instrumentation
Authors: Srinivasan Ethan S. , Wang Timothy Y. , Rapoport Anna , Erickson Melissa M. , Abd-El-Barr Muhammad M. , Shaffrey Christopher I. , Than Khoi D. 
Published: July 2022

In this video, the authors highlight the operative treatment of a 55-year-old man with chronic osteomyelitis discitis. The operation entailed a minimally invasive lateral retroperitoneal transpsoas approach for L3 and L4 corpectomies, L2–5 interbody fusion, and L2–5 minimally invasive posterior instrumentation. The operation proceeded in two stages, beginning in the lateral position with corpectomy of the L3 and L4 vertebral bodies and placement of a corpectomy cage. After closure of this access wound, the patient was turned to a prone position for the posterior element of the operation. Posterior instrumentation was placed with pedicle screws at L2 and L5.
The video can be found here: https://stream.cadmore.media/r10.3171/2022.3.FOCVID2210
Navigated retrodiaphragmatic/retroperitoneal approach for the treatment of symptomatic kyphoscoliosis: an operative video
Authors: Strong Michael J. , Linzey Joseph R. , Zaki Mark M. , Joshi Rushikesh S. , Ward Ayobami , Yee Timothy J. , Khalsa Siri Sahib S. , Saadeh Yamaan S. , Park Paul 
Published: July 2022

Retropleural, retrodiaphragmatic, and retroperitoneal approaches are utilized to access difficult thoracolumbar junction (T10–L2) pathology. The authors present a 58-year-old man with chronic low-back pain who failed years of conservative therapy. Preoperative radiographs demonstrated significant levoconvex scoliosis with coronal and sagittal imbalance. He underwent a retrodiaphragmatic/retroperitoneal approach for T12–L1, L1–2, L2–3, and L3–4 interbody release and fusion in conjunction with second-stage facet osteotomies, L4–5 TLIF, and T10–iliac posterior instrumented fusion. This video focuses on the retrodiaphragmatic approach assisted by 3D navigation.
The video can be found here: https://stream.cadmore.media/r10.3171/2022.3.FOCVID2215
Ischemia-induced inflammation in arteriovenous malformations
Authors: Rodemerk Jan , Oppong Marvin Darkwah , Junker Andreas , Deuschl Cornelius , Forsting Michael , Zhu Yuan , Dammann Philipp , Uerschels Anne , Jabbarli Ramazan , Sure Ulrich , Wrede Karsten H. 
Published: July 2022

OBJECTIVE
The pathophysiology of development, growth, and rupture of arteriovenous malformations (AVMs) is only partially understood. However, inflammation is known to play an essential role in many vascular diseases. This feasibility study was conducted to investigate the expression of enzymes (cyclooxygenase 2 [COX-2] and NLRP3 [NOD-, LRR-, and pyrin domain–containing protein 3]) in the AVM nidus that are essential in their inflammatory pathways and to explore how these influence the pathophysiology of AVMs.

METHODS
The study group comprised 21 patients with partially thrombosed AVMs. The cohort included 8 ruptured and 13 unruptured AVMs, which had all been treated microsurgically. The formaldehyde-fixed and paraffin-embedded samples were immunohistochemically stained with a monoclonal antibody against COX-2 and NLRP3 (COX-2 clone: CX-294; NLRP3: ab214185). The authors correlated MRI and clinical data with immunohistochemistry, using the Trainable Weka Segmentation algorithm for analysis.

RESULTS
The median AVM volume was 2240 mm3. The proportion of NLRP3-positive cells was significantly higher (26.23%–83.95%), compared to COX-2 positive cells (0.25%–14.94%, p < 0.0001). Ruptured AVMs had no higher expression of NLRP3 (p = 0.39) or COX-2 (p = 0.44), compared to nonruptured AVMs. Moreover, no patient characteristics could be reported that showed significant correlations to the enzyme expression.

CONCLUSIONS
NLRP3 consistently showed an approximately 10-fold higher expression level than COX-2, making the inflammatory process in AVMs appear to be mainly associated with ischemic (NLRP3)–driven rather than with mechanical (COX-2)–driven inflammatory pathways. No direct associations between NLRP3 and COX-2 expression and radiological, standard histopathological, or patient characteristics were found in this cohort.
More pronounced hemodynamic alterations in patients with brain arteriovenous malformation–associated epilepsy
Authors: Sebök Martina , Germans Menno Robbert , Niftrik Christiaan Hendrik Bas van , Kulcsár Zsolt , Regli Luca , Fierstra Jorn 
Published: July 2022

OBJECTIVE
Epileptic seizures in patients with brain arteriovenous malformations (bAVMs) may be caused by hemodynamic alterations due to the complex angioarchitecture of bAVMs. In particular, an arterial steal phenomenon and venous outflow disruption may play an etiological role in seizure development but remain challenging to demonstrate quantitatively. Blood oxygenation level–dependent (BOLD) cerebrovascular reactivity (CVR) imaging is an emerging technique that can measure both arterial steal phenomenon (as a paradoxical BOLD signal decrease during a vasodilatory stimulus) and impaired perinidal BOLD-CVR (which has been found in the presence of venous congestion on conventional angiography in bAVM patients with epilepsy). By applying this innovative BOLD-CVR technique, the aim is to better study CVR patterns and their correlation with morphological features on conventional angiography in patients with bAVM with and without epilepsy.

METHODS
Twenty-two patients with unruptured and previously untreated bAVMs (8 with and 14 without epilepsy) were included in this case-control study. Quantitative CVR measurements were derived from BOLD functional MRI volumes using a novel standardized and precise hypercapnic stimulus (i.e., % BOLD/mm Hg CO2). In addition, 22 matched healthy controls underwent an identical BOLD-CVR study. Evaluation of venous congestion was performed on conventional angiography for all patients with bAVM.

RESULTS
Patients with bAVM-associated epilepsy showed impaired whole-brain BOLD-CVR compared to those in the nonepilepsy group, even after correction for AVM volume and AVM grade (epilepsy vs nonepilepsy group: 0.17 ± 0.07 vs 0.25 ± 0.07, p = 0.04). A BOLD-CVR–derived arterial steal phenomenon was observed in 2 patients with epilepsy (25%). Venous congestion was noted in 3 patients with epilepsy (38%) and in 1 patient without epilepsy (7%; p = 0.08).

CONCLUSIONS
These data suggest that whole-brain CVR impairment, and more pronounced hemodynamic alterations (i.e., arterial steal phenomenon and venous outflow restriction), may be more present in patients with bAVM-associated epilepsy. The association of impaired BOLD-CVR and bAVM-associated epilepsy will need further investigation in a larger patient cohort.
Endovascular treatment as the first-line approach for cure of low-grade brain arteriovenous malformation
Authors: Razavi Seyed Ali Shariat , Mirbolouk Mohammad Hossein , Gorji Reza , Ebrahimnia Feizollah , Sasannejad Payam , Zabihyan Samira , Seraj Farid Qoorchi Moheb , Etemadrezaie Hamid , Esmaeilzadeh Mahla , Blanc Raphaël , Piotin Michel , Baharvahdat Humain 
Published: July 2022

OBJECTIVE
While microsurgery has been proposed as the first-line treatment for patients with low-grade (Spetzler-Martin grade I or II) brain arteriovenous malformations (bAVMs), recent studies have shown promising results for endovascular treatment (EVT) as a single proper choice for the management of this group of bAVMs. In this study, the authors evaluated the safety and efficacy of EVT as a first-line strategy for curing low-grade bAVMs at their center.

METHODS
All patients with low-grade bAVMs managed primarily by EVT between 2015 and 2021 were enrolled in this study. Patients were evaluated and treated by the same team and followed with the same protocol. The primary endpoint was the efficacy of EVT on the cure of low-grade bAVMs. The second endpoint was the safety of EVT for the treatment of low-grade bAVMs, including procedural complications and long-term clinical outcomes.

RESULTS
A total of 109 patients were enrolled and represented in the study population. The mean patient age was 31.6 ± 14.8 years. Forty-eight AVMs (44%) were Spetzler-Martin grade I and 61 (56%) were grade II. Of 99 patients who completed their EVT sessions, complete exclusion was achieved in 89 patients (89.9%). Overall, complete exclusion was achieved in 59.6% of patients after a single EVT session. At the 6-month follow-up, 106 patients (97.2%) had a favorable outcome. Four patients (4.6%) experienced transient neurological deficits, and 1 patient (0.9%) had a permanent neurological deficit.

CONCLUSIONS
EVT can be offered as the first choice of treatment for select patients with low-grade bAVMs, with a high cure rate and low morbidity.
Head and neck arteriovenous malformations: University of Tennessee experience, 2012–2022
Authors: Dawkins Demi , Motiwala Mustafa , Peterson Jeremy , Gleysteen John , Fowler Brian , Arthur Adam , Elijovich Lucas 
Published: July 2022

OBJECTIVE
Head and neck arteriovenous malformations (AVMs) are complex lesions that represent a subset of vascular anomalies (VAs). The authors present an analysis of their institutional experience managing these lesions as a multidisciplinary team.

METHODS
A retrospective chart review was performed of head and neck AVM patients treated at the authors’ institution from 2012 to 2022. Recorded data included patient demographic characteristics, details of clinical presentation, Schöbinger clinical scale and Yakes AVM classification results, and details of all endovascular and surgical treatments. The primary outcome of the study was clinical response to treatment. Angiographic occlusion and complication rates were reported. Chi-square tests were used for comparative statistics.

RESULTS
Sixteen patients (9 female, 56%) with AVMs of the head and neck presented from age 3 to 77 years. The Schöbinger stage was stage II in 56% of patients (n = 9) and stage III in 44% of patients (n = 7). The Yakes AVM classification was nidus type (2a, 2b, or 4) in 7 patients (43%) and fistula type (1, 3a, or 3b) in 9 patients (57%). The majority of patients (n = 11, 69.0%) were managed with embolization as the only treatment modality, with an average of 1.5 embolizations/patient (range 1–3). Surgical resection was employed in 5 patients (4 in combination with embolization). Symptom resolution and symptom control were achieved in 69% and 31% of patients, respectively, in the entire cohort. A radiographic cure was demonstrated in 50% of patients. There were no statistical differences in clinical outcomes or radiographic cure rates between patients treated with different modalities.

CONCLUSIONS
Head and neck AVMs can be treated successfully with a primarily endovascular management strategy by a multidisciplinary team with the goal of symptomatic control.
Cerebral vasospasm following arteriovenous malformation rupture: a population-based cross-sectional study
Authors: Dicpinigaitis Alis J. , Feldstein Eric , Shapiro Steven D. , Kamal Haris , Bauerschmidt Andrew , Rosenberg Jon , Amuluru Krishna , Pisapia Jared , Dangayach Neha S. , Liang John W. , Bowers Christian A. , Mayer Stephan A. , Gandhi Chirag D. , Al-Mufti Fawaz 
Published: July 2022

OBJECTIVE
Studies examining the risk factors and clinical outcomes of arterial vasospasm secondary to cerebral arteriovenous malformation (cAVM) rupture are scarce in the literature. The authors used a population-based national registry to investigate this largely unexamined clinical entity.

METHODS
Admissions for adult patients with cAVM ruptures were identified in the National Inpatient Sample during the period from 2015 to 2019. Complex samples multivariable logistic regression and chi-square automatic interaction detection (CHAID) decision tree analyses were performed to identify significant associations between clinical covariates and the development of vasospasm, and a cAVM–vasospasm predictive model (cAVM-VPM) was generated based on the effect sizes of these parameters.

RESULTS
Among 7215 cAVM patients identified, 935 developed vasospasm, corresponding to an incidence rate of 13.0%; 110 of these patients (11.8%) subsequently progressed to delayed cerebral ischemia (DCI). Multivariable adjusted modeling identified the following baseline clinical covariates: decreasing age by decade (adjusted odds ratio [aOR] 0.87, 95% CI 0.83–0.92; p < 0.001), female sex (aOR 1.68, 95% CI 1.45–1.95; p < 0.001), admission Glasgow Coma Scale score < 9 (aOR 1.34, 95% CI 1.01–1.79; p = 0.045), intraventricular hemorrhage (aOR 1.87, 95% CI 1.17–2.98; p = 0.009), hypertension (aOR 1.77, 95% CI 1.50–2.08; p < 0.001), obesity (aOR 0.68, 95% CI 0.55–0.84; p < 0.001), congestive heart failure (aOR 1.34, 95% CI 1.01–1.78; p = 0.043), tobacco smoking (aOR 1.48, 95% CI 1.23–1.78; p < 0.019), and hospitalization events (leukocytosis [aOR 1.64, 95% CI 1.32–2.04; p < 0.001], hyponatremia [aOR 1.66, 95% CI 1.39–1.98; p < 0.001], and acute hypotension [aOR 1.67, 95% CI 1.31–2.11; p < 0.001]) independently associated with the development of vasospasm. Intraparenchymal and subarachnoid hemorrhage were not associated with the development of vasospasm following multivariable adjustment. Among significant associations, a CHAID decision tree algorithm identified age 50–59 years (parent node), hyponatremia, and leukocytosis as important determinants of vasospasm development. The cAVM-VPM achieved an area under the curve of 0.65 (sensitivity 0.70, specificity 0.53). Progression to DCI, but not vasospasm alone, was independently associated with in-hospital mortality (aOR 2.35, 95% CI 1.29–4.31; p = 0.016) and lower likelihood of routine discharge (aOR 0.62, 95% CI 0.41–0.96; p = 0.031).

CONCLUSIONS
This large-scale assessment of vasospasm in cAVM identifies common clinical risk factors and establishes progression to DCI as a predictor of poor neurological outcomes.
De novo epilepsy after microsurgical resection of brain arteriovenous malformations
Authors: Sen Rajeev D. , Nistal Dominic , McGrath Margaret , Barros Guilherme , Shenoy Varadaraya Satyanarayan , Sekhar Laligam N. , Levitt Michael R. , Kim Louis J. 
Published: July 2022

OBJECTIVE
Seizures are the second most common presenting symptom of brain arteriovenous malformations (bAVMs) after hemorrhage. Risk factors for preoperative seizures and subsequent seizure control outcomes have been well studied. There is a paucity of literature on postoperative, de novo seizures in initially seizure-naïve patients who undergo resection. Whereas this entity has been documented after craniotomy for a wide variety of neurosurgically treated pathologies including tumors, trauma, and aneurysms, de novo seizures after bAVM resection are poorly studied. Given the debilitating nature of epilepsy, the purpose of this study was to elucidate the incidence and risk factors associated with de novo epilepsy after bAVM resection.

METHODS
A retrospective review of patients who underwent resection of a bAVM over a 15-year period was performed. Patients who did not present with seizure were included, and the primary outcome was de novo epilepsy (i.e., a seizure disorder that only manifested after surgery). Demographic, clinical, and radiographic characteristics were compared between patients with and without postoperative epilepsy. Subgroup analysis was conducted on the ruptured bAVMs.

RESULTS
From a cohort of 198 patients who underwent resection of a bAVM during the study period, 111 supratentorial ruptured and unruptured bAVMs that did not present with seizure were included. Twenty-one patients (19%) developed de novo epilepsy. One-year cumulative rates of developing de novo epilepsy were 9% for the overall cohort and 8.5% for the cohort with ruptured bAVMs. There were no significant differences between the epilepsy and no-epilepsy groups overall; however, the de novo epilepsy group was younger in the cohort with ruptured bAVMs (28.7 ± 11.7 vs 35.1 ± 19.9 years; p = 0.04). The mean time between resection and first seizure was 26.0 ± 40.4 months, with the longest time being 14 years. Subgroup analysis of the ruptured and endovascular embolization cohorts did not reveal any significant differences. Of the patients who developed poorly controlled epilepsy (defined as Engel class III–IV), all had a history of hemorrhage and half had bAVMs located in the temporal lobe.

CONCLUSIONS
De novo epilepsy after bAVM resection occurs at an annual cumulative risk of 9%, with potentially long-term onset. Younger age may be a risk factor in patients who present with rupture. The development of poorly controlled epilepsy may be associated with temporal lobe location and a delay between hemorrhage and resection.
PELATIHAN PEMANFAATAN APLIKASI GOOGLE DATA STUDIO UNTUK VISUALISASI DATA DI SMK TEKNOLOGI RIAU
Authors: Syam Febrizal Alfarasy , Yuvi Darmayunata  , Lucky Lhaura Van FC  
Published: July 2022

Pengabdian ini dilakukan di Sekolah Menengah Kejuruan (SMK) Teknologi Riau, berupa pelatihan kepada guru dan staff terhadap pemanfaatan google data studio untuk menvisualisasikan data yang ada di SMK Teknologi Riau secara online. Saat ini data yang ada di SMK Teknologi masih tersimpan di perangkat komputer yang dimiliki oleh SMK Teknologi Riau , namun data tersebut belum dapat memberikan informasi kepada civitas akademika maupun masyarakat secara langsung. Jika civitas akademika atau masyarakat ingin mendapatkan informasi terkait data yang ada di SMK Teknologi Riau, maka harus melalui staff terlebih dahulu karena hak aksesnya yang terbatas. Data yang ada juga masih dalam bentuk data mentah dan bentuk tampilan datanya juga kurang menarik. Oleh karena itu diperlukan suatu media yang dapat mengatasi hal tersebut. Pada pengabdian ini kami akan memberikan solusi dengan pemanfaatan google data studio untuk menvisualisasikan data agar lebih menarik sehingga dapat ditampilkan pada website SMK Teknologi Riau. Berdasarkan hasil kuesioner post test, pemahaman peserta terhadap aplikasi google data studio sudah baik yaitu 100% menyatakan paham tentang dasar penggunaan aplikasi. Berdasarkan pengamatan tim pengabdian, peserta sangat antusias mengikuti pelatihan yang diberikan.
PKM PELATIHAN PEMBUATAN GAME MENGGUNAKAN UNITY UNTUK SISWA SMK DI KOTA PEKANBARU
Authors: Nurliana Nasution  , Feldiansyah Bakri Nasution  , Hasan Mhd Arief 
Published: July 2022

Pengabdian Masyarakat ini mengangkat kegiatan mengenai pelatihan pembuatan Game menggunakan Game Engine Unity. Unity merupakan salah satu Game Engine terpopuler saat ini. Dikarenakan game engine ini mampu untuk menghasilkan game lintas platform sistem operasi. PKM ini diadakan bersama siswa SMK N 8 Pekanbaru. Kegiatan ini di adakan di Fakultas Ilmu Komputer Universitas Lancang Kuning. Dari kegiatan ini peserta diajarkan step-step pembuatan aplikasi menggunakan unity. Peserta diajarkan teknik instalasi, pembuatan objek dasar dan game dasar. Evaluasi kegiatan berupa beberapa tugas latihan dari pemateri yang dikumpulkan di kemudian hari. Tugas ini dikerjakan disekolah mereka masing-masing. Hasil dari penghargaan peserta ini diberikan berupa sertifikat kepada masing-masing peserta. Hasil pekerjaan projek terbaik diberikan hadiah tambahan dari pemateri.