bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recent Updates on Synthesis, Biological Activity, and Structure-activity
Relationship of 1,3,4-Oxadiazole-quinoline Hybrids: A Review
Authors: Sharma Abhishek Shankar , Salahuddin  , Mazumder Avijit , Kumar Rajnish , Datt Vimal , Shabana Km , Tyagi Sonakshi , Yar Mohammad Shahar , Ahsan Mohamed Jawed 
Published: October 2022

Abstract:
Due to their diverse applications in industrial and synthetic organic chemistry, quinoline
and 1,3,4-oxadiazole have become important heterocyclic compounds. Quinoline and 1,3,4-
oxadiazole compounds have been developed for various medical conditions such as anti-cancer,
anti-bacterial, anti-fungal, antimalarial, antioxidants, anti-HIV, anticonvulsant, antiviral, etc. The
current review includes synthetic protocols for biologically active 1,3,4-oxadiazole incorporating
quinoline hybrids with their structure-activity relationship to explore work (Mainly from 2010 to
2021) based on 1,3,4-oxadiazole-quinoline hybrids to the medicinal chemist for further research in
the development of the molecule.
Herbal Drugs to Targets in the Treatment of Cancer - A Futuristic Approach
Authors: Tiwari Anshu , Alam Md. Aftab , Kaur Awaneet , Sharma Shaweta , Yadav Shikha 
Published: October 2022

Abstract:In the last few decades, cancer has affected people globally and is the most minacious disease that affects human body cells. It is a prominent cause of death. Cancer can affect anyone anywhere in the body. Most ordinary cancers are lung, colorectal, prostate, breast, etc. There are various options for the treatment of cancer, such as chemotherapy, radiation, surgery, or hormonal therapy, but the adverse effects may be harmful and can vary considerably depending on the health outcomes of the person. Many studies have recently focused on herbal species for anticancer purposes. Several herbal components and their analogues are mostly recognised as crucial anticancer factors. However, different plants have anticancer properties. Various medicinal herbs were revealed to improve the quality of life of cancer patients. This study shows that herbal goods with related analogues are cancer-resistant compounds with in vivo or in vitro anticancer effects. His study aims to demonstrate the herbal products with related analogues as cancer-resistant compounds as novel species with in vivo or in vitro anticancer effects. This review has focused on several natural anticancer substances, besides several other organic products. Most herbs seemed to progress through the process of anti-cancer. An herbal compound analysis is often valuable for discovering new pharmacologically important materials with special pathways. It can be noted that to provide nature’s variability, chemically, components that can be associated with most targeted therapies are often developed.
Decentralized Wind Power Forecasting using Average Output Model and
Improved Stacking Ensemble Learning
Authors: Yang Jiaquan , Li Wei , Yan Yuting , Yuan Zhiyong , Su Shi , Bai Hao , Pan Shuhui , Chen Jun , Zhao Qindao 
Published: October 2022

Background:
Distributed wind farms cover a wide area, the internal units are far apart,
and the output correlation is low. With the gradual expansion of its development scale, accurate
prediction of distributed wind power has become an important means to ensure the smooth operation
of the power system.

Objective:
This paper proposes a decentralized wind power forecasting method based on cluster
analysis and multi-model stacking ensemble learning.

Method:
Firstly, the average output model of multiple units is established through cluster analysis
to eliminate redundant and repetitive features; secondly, a feature complex model is established to
construct multi-dimensional combined features to fully extract feature information; then, an improved
Stacking integrated learning model is proposed. Sets and model sets, while reducing the
amount of model calculation, give full play to the feature adaptability of different models.

Results:
The results of the proposed model are analyzed by comparison with traditional machine
learning models such as SVM. Root Mean Square Error (RMSE) can be reduced by up to 6.3%

Conclusion:
The results show that, compared with traditional single-model forecasting, the decentralized
wind power forecasting method based on cluster analysis and multi-model stacking ensemble
learning has higher forecasting accuracy.
Newly-onset Autoimmune Diabetes Mellitus Triggered by COVID 19 Infection:
A Case-based Review
Authors: Akkuş Gamze 
Published: October 2022

:
The devastating global pandemic Coronavirus disease 2019 (COVID 19) isolated in China in
January 2020 is responsible for an outbreak of pneumonia and other multisystemic complications. The
clinical picture of the infection has extreme variability: it goes from asymptomatic patients or mild forms
with fever, cough, fatigue and loss of smell and taste to severe cases ending up in the intensive care unit
(ICU). This is due to a possible cytokine storm that may lead to multiorgan failure, septic shock, or thrombosis.

:
Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV -2), which is the virus that causes COVID
19, binds to angiotensin-converting enzyme 2 (ACE2) receptors, which are expressed in key metabolic
organs and tissues, including pancreatic beta cells, adipose tissue, the small intestine and the kidneys.
Therefore it is possible to state that newly-onset diabetes is triggered by COVID 19 infection.

:
Although many hypotheses have clarified the potential diabetogenic effect of COVID 19, a few observations
were reported during this pandemic. Two male patients admitted to us with devastating hyperglycemia
symptoms were diagnosed with type 1/autoimmune diabetes mellitus within 3 months following
COVID 19 infection. Autoantibodies and decreased C peptide levels were detected in these patients. We
speculated that several mechanisms might trigger autoimmune insulitis and pancreatic beta-cell destruction
by COVID 19 infection. We aim to raise awareness of the possible link between SARS-CoV-2 and newly
onset type 1 diabetes mellitus. Further studies are needed to determine a more definitive link between the
two clinical entities.
Assessment of cognitive disorders in fragile patients with arterial hypertension and chronic heart failure
Authors: Safronenko V. A. , Chesnikova A. I. , Godunko E. S. , Hhatlamadzhiyan V. V. 
Published: October 2022

Objective: assessment of cognitive impairment (CI) in «fragile» patients with arterial hypertension (AH) and chronic heart failure (CHF).Materials and methods: the study involved 168 patients with hypertension and senile asthenia syndrome (SSA) over the age of 80 years. Taking into account the presence of CHF, all patients were ranked into two groups: group 1 – patients with hypertension, CSA and CHF (n=84), group 2 – patients with hypertension, CSA without CHF (n=84). Cognitive functions (CF) were assessed by neuropsychological testing using the MMSE short scale, which determines the patient’s mental status.Results: anemia (p=0.033), AF (p=0.003) and type 2 diabetes (p=0.042) were more common in group 1 patients, and higher BMI (p<0.001) in group 2. CI was recorded in 95.2% of patients (50.6% non-dementic CI, 48.8% mild dementia, and 0.6% moderate). In patients with CAS, AH and CHF, mild dementia was more often detected (p=0.005), and in patients without CHF, non-dementic CI was more often detected (p=0.000). In addition, in the 1st group of patients, a decrease in concentration of attention (p=0.036), and spatial and visual memory (p=0.048) was more often recorded in comparison with patients without CHF. Women of the 1st group, in comparison with men, more often had a mild degree of dementia (p=0.050). In men, there was a clear trend towards a more frequent occurrence of non-dementic CI (p=0.068). In addition, in the same group, 2.3% of women had moderate dementia, and 7.5% of men had no CI at all. Among patients with SSA and AH, but without CHF, there were no gender differences in the incidence of cognitive impairment.Conclusions: the obtained results of the study indicate the adverse effect of CHF on cognitive functions in senile patients with AH and CAS. Timely and optimal treatment of not only hypertension, but also CHF will reduce the risk of development and severity of cognitive impairment in such patients.
Microstructural Characterization and Mechanical Properties of Similar and Dissimilar Al Alloys Joined using Friction Stir Welding
Authors: Hassan Kharia Salman 
Published: October 2022

ان تاثير القذف بالكرات الفولاذية السابق لعملية اللحام وكذلك سرعته الخطية والدورانية على الخواص الميكانيكية والمتالورجية لوصلات لحام انتجت بطريقة الخلط الاحتكاكي لسبائك الالمنيوم المتشابهة وغير المتشابهة وذات المتانة العالية - AA2024 T3–AA6061 .تم تحضير عددا من الصفائح من السبائك المختارة بابعاد ملم وان عدد من هذه السبائك تعرضت الى القذف بكرات فولاذية قطرها (1.25) ملم ولمدة (15) دقيقة بعدها عدة وصلات لحام انجزت من الصفائح غير المتماثلة والمتماثلة المقذوفة وغير المقذوفة وبسرعة لحام (28,40,56)mm/min مع تثبيت السرعة الدورانية عند (1400)Rpm وقد انتخبت سرعة لحام (40)mm/min وبالسرعة الدورانية نفسها (1400)Rpm في عملية لحام صفائح اللحام التي تم قذفها لبيان تاثير عملية القذف على اما الخواص الميكانيكية فقد تمت عملية اللحام بواسطة ماكنة تفريز عمودية وتم قياس التغير في درجة الحرارة في مناطق اللحام باستخدام مزدوج حراري وكذلك اجري اختبار الصلادة المايكروية والشد ومن النتائج التي تم الحصول عليها وجد انخفاض في الخواص الميكانيكة عند زيادة في السرعة وان افضل نتيجة ظهرت عند سرعة خطية مقدارها (28m/min) وان عملية القذف بالكرات الفولاذية قبل عملية اللحام ساهمت في تحسين الخواص الميكانيكية لدرجة مقاربة لنتائج المعدن الاساس وقد وجد تحسن في الخواص الميكانيكة عند زيادة السرعة الدورانية.
The Political Role of the Survey Agency in Indonesia Democracy
Authors: Murod Ma'mun , Andriyani Lusi , Gunanto Djoni , Usni  , Hamid Norsiah Abdul 
Published: October 2022

This article has main points of discussion on issues related to how political survey institutions should operate to support democracy in Indonesia. The purpose of the study in this article is to map the ideal operational pattern of political survey institutions to support democracy in Indonesia. By using the literature study method, this article collects various literature sources to draw conclusions from these problems. This article has found that there are various ethical violations in political surveys that have been carried out for some time. The problem relates to the unholy alliance with political consultants, contemporary business models, manipulation and misleading survey results, and survey method techniques. The recommendation from this article is that political pollsters should prioritize integrity, transparency, and accountability over profit. This will certainly be positively correlated with developing democracy in Indonesia.
FAKTOR-FAKTOR YANG MEMPENGARUHI KEPUTUSAN INVESTASI CRYPTOCURRENCY PADA KAUM MILENIAL
Authors: Perayunda I Gusti Ayu Diah , Mahyuni Luh Putu 
Published: October 2022

Penelitian ini bertujuan untuk menguji secara komperhensif faktor-faktor yang mempengaruhi keputusan investasi cryptocurrency pada kaum milenial di kota Denpasar. Data dikumpulkan dengan menggunakan instrumen kuisioner berbasis web google form yang melibatkan 100 responden investor milenial yang aktif berinvestasi jual beli cryptocurrency di kota Denpasar. Data diolah dan dianalisis menggunakan aplikasi software SmartPLS3. Hasil penelitian menunjukkan financial experience dan overconfidence tidak berpengaruh terhadap keputusan investasi cryptocurrency. Hanya risk tolerance yang berpengaruh terhadap keputusan investasi cryptocurrency. Temuan lain juga menunjukkan bahwa overconfidence dan risk tolerance tidak mampu memediasi hubungan antara financial experience terhadap keputusan investasi cryptocurrency. Adanya penelitian ini berimplikasi pada tingkat wawasan dan kesadaran akan tingkat risiko investasi yang dimiliki oleh investor, sehingga keputusan yang diambil dapat lebih efektif, mengingat cryptocurrency merupakan investasi yang bersifat high risk. Penelitian ini menawarkan model empiris yang menjelaskan faktor yang mempengaruhi keputusan investasi cryptocurrency pada kaum milenial dengan menggunakan model penelitian yang menggabungkan faktor psikologis dan demografis yang menggunakan dua variabel mediasi pada investasi cryptocurrency, sehingga penelitian ini penting dilakukan guna menambah kontribusi pada kajian literatur.

Kata kunci: financial experience, overconfidence, risk tolerance, keputusan investasi cryptocurrency, cryptocurrency, milenial
A point-of-care dot blot ELISA assay for detection of protective antibody against canine adenovirus, canine parvovirus, and canine distemper virus is diagnostically accurate
Authors: Egerer Azizeh , Schaefer Zoie , Larson Laurie 
Published: October 2022

Abstract

OBJECTIVE
To determine diagnostic accuracy of a point-of-care antibody-screening test by determining sensitivity, specificity, and overall accuracy when compared to reference standard tests for antibody against core vaccine viruses canine adenovirus (CAV), canine parvovirus (CPV), and canine distemper virus (CDV). A further aim was to provide the practitioner with information to guide selection of vaccinal antibody testing methods.

SAMPLES
Canine sera from across North America were submitted to a fee-for-service titer-testing laboratory. Samples came from healthy pet dogs with known core vaccination history (n = 431) as well as unvaccinated dogs held in isolation (132). This study examined a total of 563 samples for CDV/CPV and 183 for CAV.

PROCEDURES
Serum virus neutralization assays determined antibody titers for CDV and CAV. Hemagglutination inhibition assay determined antibody titers against CPV. All sera were also tested by point-of-care dot blot ELISA (index test).

RESULTS
For all 3 viral antigens, the index test provided sensitivity ranging from 96.03% to 96.75% and specificity ranging from 87.50% to 94.33%. Overall accuracy ranged from 93.43% to 95.91%.

CLINICAL RELEVANCE
The index test correlates well with reference standard tests and is a reliable, rapid screening test for detection of protective vaccinal antibody against CAV, CDV, and CPV in healthy dogs over 20 weeks of age. An accurate assessment of immunity allows clinicians to administer core vaccines appropriately as needed, avoiding unnecessary risk of adverse vaccine events.
Equine umbilical cord mesenchymal stem cells demonstrate safety and efficacy in the treatment of canine osteoarthritis: a randomized placebo-controlled trial
Authors: Punzón Eva , Salgüero Raquel , Totusaus Xavier , Mesa-Sánchez Cristian , Badiella Llorenç , García-Castillo María , Pradera Almudena 
Published: October 2022

Abstract

OBJECTIVE
To demonstrate the efficacy and safety of mesenchymal stem cells (MSCs) for xenogeneic use with intra-articular administration in dogs with osteoarthritis.

ANIMALS
80 client-owned dogs with naturally occurring osteoarthritis in elbow or hip.

PROCEDURES
A multicentric, double-blinded, parallel, randomized and placebo-controlled clinical trial was performed. After intra-articular injection of equine umbilical cord MSCs, dogs were reexamined at weeks 4, 8, and 12 using a force platform (gait analysis), orthopedic assessment, and validated owner questionnaire. Eighteen months after treatment, a long-term follow-up was done.

RESULTS
Best results were obtained 8 weeks after treatment, where 63% of the patients showed an improvement in the gait analysis. Also 8 weeks after treatment, 77% of the dogs improved in the orthopedic examination; 65% of the owners considered that the treatment improved their pet’s quality of life 8 weeks after treatment. The long-term follow-up revealed that 59% of the owners observed a duration of effect longer than 6 months after a single intra-articular injection of equine umbilical cord MSCs. No systemic or permanent adverse events were detected at any time point.

CLINICAL RELEVANCE
Results of this study demonstrated the safety and efficacy of intra-articular administration of xenogeneic MSCs for the treatment of canine osteoarthritis.
High Simulation Reconstruction of Crowd Animation Based on Optical Flow Constraint Equation
Authors: Wang Jiajie 
Published: October 2022

Abstract
The amount of information available in modern life is very high. And people's knowledge about what kind of genre they like or prefer, the richness of content and the frequency of use will affect the quality of their animation works and their style. Therefore, how to make animation reach a higher level of simulation has become one of the topics of social concern nowadays; with the advent of mobile Internet era, more and more people like this social platform, and in this environment, we need to personalize ourselves and integrate into it faster through various technical means. In this paper, researchers focus on the reconstruction of crowd movement trajectory based on the optical flow constraint equation (SDH) after modification. Since lasers, cameras and other devices have high-intensity pixel resolution characteristics as well as better directional characteristics, we can use these features to design and build the function; then we can complete the relevant actions according to the prototype model under certain conditions, realize the simulation of the scene according to its requirements, and finally complete the required functions of the whole system. Finally, the feasibility and effectiveness of the optical flow constraint equation and the optimized action model in practical applications are verified through experiments; at the same time, this also provides reference values for relevant staff.
Green building considering image processing technology combined with CFD numerical simulation
Authors: Yin Xiaojing 
Published: October 2022

Abstract
In order to solve the increasing phenomenon of building energy consumption, the green building is deeply studied by combining image processing technology and CFD digital simulation technology. The research status of green building design is compared. The optimal green building design scheme is obtained by introducing CFD numerical simulation method, introducing finite element Navier -Stokes equation, equation turbulence model and so on. This paper analyzes the design optimization of modern green buildings, and explores the application of CFD numerical simulation technology in green building design. In practice, combined with the practice of CFD in the research project, this paper studies the five evaluation indexes of CFD technology in green building design, such as land saving, water saving, energy saving, material saving and indoor environment. This paper verifies the possibility of using CFD technology in the process of green building design, and promotes the application of CFD in green building design by using CFD technology to assist green building evaluation standards in green building design.
Service Quality Towards Banking Customer Satisfaction And Loyalty PT. Bank Mandiri
Authors: Syamsul Alam  , Naninsih Nur , Dewi Pratiwi Indriasari  
Published: October 2022

The research was conducted with the aim of knowing the quality of service that uses the dimensions of tangible, realibility, responsiveness, assurance and empathy for customer satisfaction and customer loyalty at PT. Bank Mandiri KC Kartini Makassar. The research population is the customers of PT. Bank Mandiri KC Kartini Makassar as many as 50,810 customers. Sampling was carried out using incidental sampling technique, using samples based on chance or incidental meeting of respondents with researchers at the research location as many as 150 customers. The data analysis method that will be used in this study is to use a structural equation model. Data analysis was performed using descriptive and inferential statistical analysis (applying Structural Equation Modeling (SEM) using the Smart PLS Version 3.0 program). The results showed that physical evidence, reliability, responsiveness, assurance, and empathy had a positive and significant impact on customer satisfaction. Meanwhile, physical evidence, reliability, responsiveness, assurance, and empathy have a positive and significant effect on customer loyalty. The management can be given a training or training for employees, so that employees are better trained to serve customers quickly. The quality of service can also affect employee performance because quality employee performance will create satisfaction with customers. Customer satisfaction can be created /formed through factors that can affect these variables such as service quality and customer loyalty.
Mexican-American Moderates and the Shaping of Federal Education Policy: The Case of the May 25, 1970 Memorandum
Authors: San Miguel Jr Guadalupe 
Published: October 2022

During the past several decades, historians have investigated various aspects of the Chicano movement. In most of these studies, the important role that moderate liberal activists have played in promoting significant social change during the same period has been slighted. By moderate liberal activists, I mean those who depended on the federal government to help solve the problems facing the Mexican-American community, trusted mainstream institutions and political leaders to eliminate discrimination, and, most importantly, rejected the politics of protest. Little is known about these individuals. Who were these men and women, and how did they contribute to the struggle for social justice and educational equality?
The following study examines the role that some moderate liberal educators played in promoting school reform during the height of the Chicano movement. It focuses on the drafting of the May 25, 1970 memorandum and the role played by Mexican Americans in shaping its development. This memorandum was the first major policy developed by the Office for Civil Rights to deal with the issue of discrimination against linguistically distinct children in the public schools. It clarified the Department of Health, Education, and Welfare’s (HEW) position on the responsibility of local school districts to “provide equal educational opportunity to national origin minority group children deficient in English language skills.” I argue that while Mexican- American moderates did not play a direct role in the formulation of this policy due to their exclusion from federal agencies prior to the 1960s, they did play a crucial role in its enforcement. Their involvement in the implementation of the memorandum was the origins of meaningful Mexican-American participation in the shaping of educational policies at the national level.
The role of socio-psychological capital in the debt behavior of the individual
Authors: Gagarina M. A. 
Published: October 2022

Introduction.The article provides an analysis of the role of socio-psychological capital in different types of debt behavior: borrowing and lending, as well as fulfilling debt obligations.Materials and Methods.The study was carried out with the participation of 2 samples: N=1971 (45.0% males, from 18 to 54 years old, M=25.9; SD=5.6) and N=3022 (50.5% males; from 18 to 84 years, M=40.6; SD=11.8). Based on collected data, the respondents were divided into borrowers and non-borrowers, debtors and payers, lenders and non-lenders. Quantitative indicators of bonding and bridging social capital; social, institutional and generalized trust; global identity and identification with Russia were assessed. Data processing was done in SPSS 23.0.Results.Borrowers have a higher level of generalized and social trust and a higher level of global and civic identity than non-borrowers. Payers have a higher level of generalized and social trust, and trust in credit institutions than debtors. Lenders have higher level of all types of trust and a more pronounced global and civic identity than non-lenders. People with contrasting variants of different types of debt behavior do not differ in strong and weak social ties.Discussion and Conclusions.The results obtained are compared with the data of domestic and foreign publications. The conducted study contributes to the development of the concept of sociopsychological capital, supplementing it with data on the different level of trust and identity in people with different debt behavior.