bluuebunny/crossref_metadata_2025_split huggingface dataset:
A novel near field radiation shaping technique by using data driven surrogate based optimization for nondestructive hyperthermia
Authors: Unal Mehmet , Mahouti Peyman , Turk Ahmet Serdar 
Published: September 2022

AbstractHerein, a novel and computationally efficient near field shaping technique for nondestructive hyperthermia applications is presented. The aim of nondestructive hyperthermia studies is to treat cancer cells in the body without damaging the healthy cells using the focused near‐field characteristic of the antenna array. However, optimal near field shaping requires an optimization process for having accurately focus the energy into the desired coordinates, which is, a computational expensive and inefficient task due to the nature of full‐wave electromagnetic (EM) analysis. To enable computationally efficient, and accurate near field shape optimization, a surrogate model is required. To achieve this, the near field radiation of the designed horn antenna array in free space is obtained by using a fast and reliable technique, analytical regularization method (ARM). After that, by using Artificial Neural Network based regression algorithm, a data driven surrogate model is created using the data samples generated by ARM. By this means, near field shaping optimization for focusing the energy to the region where the tumor is located can be achieved, as a multi‐objective optimization problem to be solved via data driven surrogate model assisted optimization techniques. The performance results of K‐fold validation and hold‐out data sets for proposed data driven surrogate model are calculated using Mean Absolute Error metric which are obtained as 0.9 × 10−3 and 1.4 × 10−3 respectively. By observing the presented study case scenario, after 10 min of illumination with antenna array with optimally selected configurations, the targeted area (position of tumor) had reached to the critical temperature of 43 Celsius. Thus, it can be said that the proposed method is an efficient method, both in terms of (1) destroying tumor cells by heating without damaging the healthy cells, and (2) being a computationally efficient method.
Sex‐specific behavioral, neurobiological, and cardiovascular responses to chronic social stress in mice
Authors: Helman Tessa J. , Headrick John P. , Vider Jelena , Peart Jason N. , Stapelberg Nicolas J. C. 
Published: September 2022

AbstractPsychosocial stress promotes and links mood and cardiovascular disorders in a sex‐specific manner. However, findings in animal models are equivocal, in some cases opposing human dimorphisms. We examined central nervous system (CNS), behavioral, endocrine, cardiac, and hepatic outcomes in male or female C57Bl/6 mice subjected to chronic social stress (56 days of social isolation, with intermittent social confrontation encounters twice daily throughout the final 20 days). Females exhibited distinct physiological and behavioral changes, including relative weight loss, and increases in coronary resistance, hepatic inflammation, and thigmotaxic behavior in the open field. Males evidence reductions in coronary resistance and cardiac ischemic tolerance, with increased circulating and hippocampal monoamine levels and emerging anhedonia. Shared CNS gene responses include reduced hippocampal Maoa and increased Htr1b expression, while unique responses include repression of hypothalamic Ntrk1 and upregulation of cortical Nrf2 and Htr1b in females; and repression of hippocampal Drd1 and hypothalamic Gabra1 and Oprm in males. Declining cardiac stress resistance in males was associated with repression of cardiac leptin levels and metabolic, mitochondrial biogenesis, and anti‐inflammatory gene expression. These integrated data reveal distinct biological responses to social stress in males and females, and collectively evidence greater biological disruption or allostatic load in females (consistent with propensities to stress‐related mood and cardiovascular disorders in humans). Distinct stress biology, and molecular to organ responses, emphasize the importance of sex‐specific mechanisms and potential approaches to stress‐dependent disease.
From target to actor: Contagion of honesty and deception across buyer–supplier negotiations
Authors: Ried Leopold , Eckerd Stephanie , Kaufmann Lutz , Carter Craig R. 
Published: September 2022

AbstractUnderstanding negotiators' decision‐making processes in buyer–supplier relationships has been of key interest to behavioral operations and supply chain management researchers. We hypothesize that through the exposure to various counterparts in the supply chain network, negotiators' behaviors are influenced by others' behaviors and prone to behavioral contagion—where the target adopts the behavior he/she is subjected to and exhibits it toward a nonpartisan counterpart. This paper examines such contagion where targets turn into actors of honesty and deception across buyer–supplier negotiations. We analyzed text responses from two studies employing scenario‐based negotiation experiments with 350 and 424 individuals with B2B sales experience and tested for the effects of previously received behavior (honesty/deception) and different frequency levels of the received behavior. Our results show contagion effects for honesty and deception in both studies. These effects are largely independent from the frequency with which the behaviors have been received, suggesting that a low stimulus frequency suffices to induce contagion of honest and deceptive behaviors across buyer–supplier negotiations. Interestingly, in contrast to our hypothesized key mechanism based on the extant literature, neither injunctive nor descriptive social norms mediated the relationship between received and acted behaviors. We offer alternative explanations and discuss implications for theory and practice.
Short and long‐term outcomes of prophylactic total gastrectomy in 54 consecutive individuals with germline pathogenic mutations in the CDH1 gene
Authors: Stillman Mason D. , Kusche Nicole , Toledano Sabrina , Hilfrank Kimberly J. , Yoon Changhwan , Gabre Joel T. , Rustgi Sheila D. , Hur Chin , Kastrinos Fay , Ryeom Sandra W. , Yoon Sam S. 
Published: September 2022

AbstractBackgroundGermline mutation of CDH1 is rare and leads to hereditary diffuse gastric cancer (DGC).MethodsPatients (pts) with CDH1 mutation who underwent multidisciplinary counseling followed by open prophylactic total gastrectomy (PTG) by a single surgeon were reviewed.ResultsFifty‐four pts with a median age of 41 years (16–70 years) underwent PTG between 2006 and 2021. Median operative time was 161 min, and median hospital stay was 7 days (range 6–12). There were 5 complications (9.2%) within 30 days, and two complications (pulmonary embolism and pancreatitis) required readmission. There were no anastomotic leaks. The pathologic analysis of the first 10 pts included the entire gastric mucosa, revealing a median of 15 foci of DGC (range 5–136). The subsequent 44 pts with more limited analysis had a median of 2 foci (range 0–5), and two pts (3.7%) had no foci identified. Median maximum weight loss was 19%. In long‐term follow‐up (median 4.6 years) of 20 pts, median global QOL was 2.0 (very good), the majority had persistent difficulty with certain foods or liquids, and all stated they would again elect PTG over surveillance endoscopy.ConclusionsPTG can be performed safely at high‐volume referral centers with very good QOL but nutritional sequelae persist.
Benefits of Side‐Firing Optical Fibers in Endoscopic Laser Treatment of the Larynx
Authors: DeVore Elliana Kirsh , Chiluisa Alex J. , Minch Emily V. , Mihaleva Rositsa , Do Hoang , Tougas Ryan , Fichera Loris , Carroll Thomas L. 
Published: September 2022

ObjectiveTo elucidate potential tissue coverage of side‐firing optical fibers in office‐based endoscopic laser treatment of larynx, as well as to demonstrate their enhanced ability to address challenging anatomic areas.MethodWe performed a comparative study of four different fiber designs: a traditional forward‐facing fiber, and three side‐firing fibers that emit light at an angle of 45°, 70°, and 90°, respectively. The study was conducted in simulation, using eight three‐dimensional models of the human larynx generated from microtomography x‐ray scans. A computer program simulated the insertion of the endoscope into the larynx, and the Möller–Trumbore algorithm was used to simulate the application of laser light.ResultsSide‐firing laser fibers increased potential tissue coverage by a mean of 50.2 (standard deviation [SD] 25.8), 73.8 (SD 41.3), and 84.0 (SD 47.6) percent for angles of 45°, 70°, and 90°, respectively, compared to forward‐facing fibers. Angled fibers provided access to areas of the larynx considered difficult to address by traditional methods, including the infraglottis, laryngeal ventricle, and right vocal fold.ConclusionSimulation results suggest that side‐firing optical fibers have the potential to enhance anatomical access during in‐office endoscopic laser procedures in the larynx. Further research is needed to better understand the benefits and any potential risks or contraindications of side‐firing optical fibers.Level of EvidenceNA Laryngoscope, 133:1205–1210, 2023
Voluntary Cough Testing as a Clinical Indicator of Airway Protection in Cervical Spinal Cord Injury
Authors: Pitts Laura , Hamilton Valerie K. , Walaszek Erin A. , Watts Stephanie , Cherney Leora R. 
Published: September 2022

ObjectiveVoluntary cough testing (VCT) may be useful for determining aspiration risk in neurogenic dysphagia; however, has yet to be investigated in traumatic cervical spinal cord injury (tCSCI). The study explored if VCT may elucidate swallowing safety and kinematics related to airway protection in tCSCI survivors.MethodsTen inpatients, 13–73 days post‐tCSCI (7 incomplete injuries), completed VCT and a modified barium swallowing study that was analyzed via the Penetration Aspiration Scale (PAS) and norm‐referenced measures of swallowing events related to airway protection. Spearman rho correlations explored relations among cough airflow, median PAS, and airway protection. Mann–Whitney U tests explored group differences based on clinical airway invasion (PAS > 2) and receiver operating characteristic statistics probed the sensitivity/specificity of VCT measures.ResultsSafe (PAS > 2) and unsafe swallowers differed by cough volume acceleration (CVA) for the total sample and by inspiratory duration for incomplete injuries (p = 0.03, r > 0.7). A cut‐off value of 24.8 L/s for CVA predicted airway invasion (AUC = 0.917, p = 0.03) with sensitivity = 100%/specificity = 75%. CVA correlated with delayed laryngeal vestibule closure during swallowing for both the total sample and for incomplete injuries (rs > 0.6, p < 0.05). Blunted peak flow and prolonged cough phases were associated with disordered laryngeal kinematics and prolonged bolus transit during swallowing (p < 0.05).ConclusionsReduced CVA, blunted peak flow, and prolonged cough phases reflected PAS and disrupted mechanisms of airway protection in tCSCI survivors, demonstrating promise for VCT as a clinical assessment for post‐tCSCI dysphagia.Level of Evidence3 Laryngoscope, 133:1434–1441, 2023
Tracheotomy care simulation training program for inpatient providers
Authors: Tiu Ryan Alyson‐Yao , Meyer Tanya Kim , Mayerhoff Ross M. , Ray Joel C. , Kritek Patricia A. , Merati Albert Lincoln , Sardesai Maya Guirish 
Published: September 2022

AbstractObjectivesTracheotomy complications can be life‐threatening. Many of these complications may be avoided with proper education of health care providers. Unfortunately, access to high‐quality tracheotomy care curricula is limited. We developed a program to address this gap in tracheotomy care education for inpatient providers. This study aimed to assess the efficacy of this training program in improving trainee knowledge and comfort with tracheotomy care.MethodsThe curriculum includes asynchronous online modules coupled with a self‐directed hands‐on simulation activity using a low‐cost tracheotomy care task trainer. The program was offered to inpatient providers including medical students, residents, medical assistants, nurses, and respiratory therapists. Efficacy of the training was assessed using pre‐training and post‐training surveys of learner comfort, knowledge, and qualitative feedback.ResultsData was collected on 41 participants. After completing the program, participants exhibited significantly improved comfort in performing tracheotomy care activities and 15% improvement in knowledge scores, with large effect sizes respectively and greater gains among those with little prior tracheotomy care experience.ConclusionThis study has demonstrated that completion of this integrated online and hands‐on tracheotomy simulation curriculum training increases comfort and knowledge, especially for less‐experienced learners. This training addresses an important gap in tracheotomy care education among health care professionals with low levels of tracheotomy care experience and ultimately aims to improve patient safety and quality of care. This curriculum is easily transferrable as it requires only access to the online modules and low‐cost simulation materials and could be used in other hospitals, long‐term care facilities, outpatient clinics, and home settings.Level of evidence4.
Study of the matching performance of a microarc oxidation film/electrophoresis composite coating on magnesium alloys
Authors: Dong Kaihui , Cheng Xiaoyu , Song Yingwei , Yang Jiayu , Wang Qitong , Wang Haitao , Han En‐Hou 
Published: September 2022

AbstractThe combination of a microarc oxidation (MAO) film and water‐based electrophoresis painting (EP) technology is a promising surface treatment for magnesium alloys, but the matching performance between them has not been investigated systematically. For fabricating the optimal composite coating, the influence of the MAO film condition and electrophoresis parameters on the overall performance of the composite coating was investigated by scanning electron microscopy, finite element modeling, electrochemical impedance spectroscopy, and immersion tests. The results indicate that the composite coating with an MAO voltage of 330 V and an EP voltage of 120 V shows the best corrosion resistance. Its excellent anticorrosion performance is attributed to the suitable thickness ratio of the MAO/EP coating and the excellent mechanical interlock effect of the MAO/EP interface. The microstructure of the MAO coating plays a key role; the uniform micropore size promotes a uniform electric field distribution in the initial electrophoresis process, which can considerably improve the sealing pore quality of the EP resin and further maximize the interfacial adhesion strength.
A novel passive shimming scheme using explicit control of magnetic field qualities with minimal use of ferromagnetic materials
Authors: Wang Yaohui , Wang Qiuliang , Chen Zhifeng , Liu Yang , Liu Feng 
Published: September 2022

PurposeIn an MRI system, the static magnetic field homogeneity is strictly required especially in ultrahigh field situations. However, owing to the engineering tolerances and system errors, the magnetic field homogeneity of a magnet usually cannot meet the imaging requirement; thus, a shimming operation is always needed.MethodsExisting passive shimming methods commonly minimize the peak‐peak variations of the magnetic fields over the diameter of spherical volume (DSV), targeting the field quality of 10–20 parts per million (ppm). However, these conventional passive shimming methods can sometimes lead to sub‐optimal field quality and iron consumption solutions. Notably, the RMS error (RMSE) value of the field uniformity is inherently unoptimized. This work proposed a novel passive shimming method that can deliver a significantly improved shimming solution by actively controlling the central magnetic field and specific magnetic field deviations in the region of interest. A detailed comparison between the conventional and proposed methods was conducted on a 9.4T human MRI superconducting magnet.ResultsThe results showed that the new solution had a significant advantage in searching for superior magnetic field homogeneity with less iron piece consumption. Significantly, the RMSE value of the magnetic field over the DSV can be substantially reduced >10 times. The proposed algorithms are also very efficient, taking only several seconds to find the shimming solution.ConclusionThe potential of the magnetic field homogeneity improvement methods will promote the development of high‐end MRI systems.
Engaging Stakeholders to Develop a Decision Support Model of Conservation Risk and Management Capacity to Prioritize Investments in Bull Trout Recovery
Authors: Brignon William R. , Davis M. Brian , Gunckel Stephanie , Dunham Jason , Meeuwig Michael H. , Allen Chris , Clements Shaun 
Published: September 2022

Abstract
Rarely are sufficient resources available to support the full suite of management actions to promote recovery of a species across its entire distribution. Decision support models are a tool that can inform natural resource management decisions with consideration of the perspectives from a variety of stakeholders who work across large geographic and jurisdictional extents. We offer an example of a decision support model that was developed by several federal and state natural resource agencies to rank Bull Trout Salvelinus confluentus core areas for prioritizing conservation investment within Oregon, USA. We engaged state-level decision makers to identify parameters that were believed to be influential in determining funding allocations for Bull Trout core areas. Parameters were linked in a model framework that was further refined with input from local Bull Trout experts with knowledge specific to the various core areas. The model produces a relative priority value that is a combination of the conservation risk to the species and the management capacity to address threats. A series of sensitivity analyses suggested that Bull Trout persistence and threat score were most influential in determining the relative priority of a core area, whereas life history and genetic diversity were least influential. One of the more powerful products from this work is an interactive Web-based application (https://das.ecosphere.fws.gov/public/obts/) that anyone can use to explore how their beliefs in parameter values will affect the relative priority of Bull Trout core areas across Oregon. Our modeling effort is an example of engaging stakeholders with different roles in species recovery and across a large geographic area to create a clearer path forward in allocating limited resources for species recovery. This approach can be employed to address a number of natural resource management situations across species and habitats.
Development of a Professional Practice Nursing Model for a University Nursing School and Teaching Hospital: A nursing methodology research
Authors: Rojas‐Rivera Alejandra , Quiroga Natalia , Echeverria Araceli , Muñoz‐Larrondo Francisca , Concha‐Gutierrez Carolina , Galiano Alejandra , Larrain Ana , Herrera Beatriz Sánchez 
Published: September 2022

AbstractAimThe aim of the study was to describe the process of developing a Professional Practice Model by a Nursing School and Nursing Department of University Hospital.Design and Method (s)This is a descriptive nursing methodology research, developed along three stages: preliminary, empirical and validation. The empirical phase used qualitative and quantitative methodology. 28 teachers from the nursing school and nurses from the hospital participated. We defined the elements of the nursing meta‐paradigm from narratives and focus group. Then, we extracted propositions regarding the nature of nursing from the relationship between the meta‐paradigm elements, which concluded in the core elements.ResultsThe core elements of this nursing professional practice model are nursing seeks the well‐being of the person, family or group; nursing is total and global, person‐centred; nursing is compassionate; nursing entails up‐to‐date, quality scientific, technical and human competencies; nursing is delivered in a teaching hospital environment, with a Christian ethical perspective.
The clinical learning environment during clinical practice in postgraduate district nursing students' education: A cross‐sectional study
Authors: Larsson Margaretha , Sundler Annelie J. , Blomberg Karin , Bisholt Birgitta 
Published: September 2022

AbstractAimTo describe and compare the clinical learning environment in community‐based home care and primary health care in postgraduate district nursing students' education.DesignCross‐sectional study design.MethodsA convenience sample of postgraduate district nursing students was derived from five Swedish universities in 2016 and 2017.ResultsThe postgraduate district nursing students were generally satisfied with the clinical learning environment in their clinical placement. In clinical placement, several factors affected the students' opportunities to learn, such as sufficiently meaningful learning situations with multidimensional content. A working environment that imposed psychosocial strain and high levels of stress among the staff negatively affected the students' learning. To further improve their learning from clinical practices, the students need preceptors who have the skills and competence required to support more advanced reflections and critical thinking on caring situations.
Convergence analysis of a fast second‐order time‐stepping numerical method for two‐dimensional nonlinear time–space fractional Schrödinger equation
Authors: Zhang Hui , Jiang Xiaoyun 
Published: September 2022

AbstractIn this article, we consider the two‐dimensional nonlinear time–space fractional Schrödinger equation with space described by the fractional Laplacian. A second‐order fractional backward difference formula in the temporal direction while Fourier spectral method in the spatial direction is proposed to solve the model numerically. In the numerical implementation, a fast method is applied based on a globally uniform approximation of the trapezoidal rule for the integral on the real line to decrease the memory requirement and computational cost. By using the generalized discrete Gronwall inequality developed by Dixon and McKee and the temporal–spatial error splitting argument, the convergence of the fast time‐stepping numerical method is also proved in a simple manner without imposing the Courant‐Friedrichs‐Lewy (CFL) condition. Finally, some numerical results are provided to support the theoretical analysis.