bluuebunny/crossref_metadata_2025_split huggingface dataset:
Der Marine Drive in Mumbai: ein bald versunkenes Kulturerbe?
Authors: Muhidine Eléonore 
Published: November 2022

Abstract
From the 1930s to the 1940s, Mumbai was a city of modern architecture marked by international influences, but also the birthplace of a modern Indian architectural style that became fully expressed after 1947. This heritage has rarely been considered by international research, despite its recent inclusion on the UNESCO World Heritage List (2018) and the very active involvement of local groups. A report published in the journal Nature in 2019 highlighted the consequences of climate change and rising water levels on the city of Mumbai, built on an artificial peninsula. Hence the urgent need to complete the task of researching, locating and digitizing sources on the modern architecture of Mumbai, a heritage doubly threatened by the effects of global warming and excessive urban development.
Wie Architekturgeschichte schreiben, wie Architekturgeschichte denken?
Authors: Fuhrmeister Christian 
Published: November 2022

Abstract
The short intervention pleads for a comprehensive analysis of architecture in the sense of an encompassing history of the built environment. Trespassing beyond the study of formal invention and mere aesthetic qualities, the paper argues for a holistic or systemic approach that aims at incorporating the many truly fundamental and foundational aspects, like capital in the form of land or financial resources, or power. Since many forces shape the building, it is a unique source in its own right that can be used, in turn, for an enhanced understanding of past societies. At the same time, this broader assessment is meaningful and relevant for us today.
The Application of Pragmatic Presupposition in Developing Critical Thinking of Writing
Authors: Song Yan , Wang Shuaiqi 
Published: November 2022

Abstract
This study aims to explore whether developing critical thinking ability from the perspective of pragmatic presupposition can help non-English majors improve their writing achievements. This empirical study employs tests as the instruments. 126 non-English majors from a key university of Shandong Province participate in the study. The results of the Ennis-Weir Critical Thinking Essay Test indicate that most subjects (95%) have inadequate or limited critical thinking ability, which leads to digression, repetitive and lengthy description, and unconvincing arguments, as well as illogical or incoherent structures in writing. After a ten-week teaching instruction from the perspective of pragmatic presupposition, students in experimental group improve their writing achievements, indicating that the instruction of critical thinking ability from the perspective of pragmatic presupposition may have certain effects on their writing performance. The study will promote the application of pragmatic presupposition to writing teaching and offer some implications for the teaching of English writing.
Embracing diversity: measuring the impact of an international immersion learning experience on nursing students’ cultural beliefs and values
Authors: Argenbright Christine , Sanford Julie , Sherwood Gwen D. , Jordan Portia Janine , Moriyama Michiko , Jiménez-Herrera Maria Francisca , Bengtsson Mariette , Lui Lee , Hart Vesna , McDonald Maria 
Published: November 2022

Abstract

Objectives
An international Nursing Leadership Collaborative covened in Japan to hold a patient safety and quality workshop for nursing students from six countries. The purpose was to measure students’ self reported beliefs reflecting sensitivity and openness to cultural diversity before and after the international experience.

Methods
A pre-post-test design was used and the Beliefs, Events, and Values Inventory was administered to international undergraduate and graduate nursing students.

Results
The group aggregate data analysis indicate that prior to the start of the workshop, the group presented itself as quite introspective and after the workshop the group reported being more sophisticated in making causal explanations about why the world works in the way it does.

Conclusions
Nursing students experienced an expanded awareness of their beliefs and values that reflect a greater degree of intercultural sensitivity for acceptance of inclusivity and diversity after the experience.
On nonnil-coherent modules and nonnil-Noetherian modules
Authors: Haddaoui Younes El , Kim Hwankoo , Mahdou Najib 
Published: November 2022

Abstract
In this article, we introduce two new classes of modules over a

ϕ

\phi

-ring that generalize the classes of coherent modules and Noetherian modules. We next study the possible transfer of the properties of being nonnil-Noetherian rings,

ϕ

\phi

-coherent rings, and nonnil-coherent rings in the amalgamated algebra along an ideal.
Forebrain Glucocorticoid Receptor Overexpression Alters Behavioral Encoding of Hippocampal CA1 Pyramidal Cells in Mice
Authors: Gavade Swapnil , Wei Qiang , Johnston Colin , Kounelis-Wuillaume Savannah , Laborc Klaudia , Baranwal Salisha , Akil Huda , Spencer-Segal Joanna L. 
Published: November 2022

AbstractGlucocorticoid signaling influences hippocampal-dependent behavior and vulnerability to stress-related neuropsychiatric disorders. In mice, lifelong overexpression of glucocorticoid receptor (GR) in forebrain excitatory neurons altered exploratory behavior, cognition, and dorsal hippocampal gene expression in adulthood, but whether GR overexpression alters the information encoded by hippocampal neurons is not known. We performedin vivomicroendoscopic calcium imaging of 1359 dorsal CA1 pyramidal cells in freely behaving male and female wild-type (WT) and GR-overexpressing (GRov) mice during exploration of a novel open field, where most CA1 neurons are expected to respond to center location and mobility. Most neurons showed sensitivity to center location and/or mobility based on single-neuron calcium amplitude and event rate, but these sensitivity patterns differed between genotypes. GRov neurons were more likely than WT neurons to display center sensitivity and less likely to display mobility sensitivity. More than one-third of these responsive GRov neurons were sensitive only to center location and not mobility, while uniquely center-sensitive neurons were rare in WT. Most center-sensitive neurons exhibited anticipatory activity, suggesting they could drive behavior. We conclude that, compared with wild-type, dorsal CA1 pyramidal cells in GRov mice preferentially respond to center location rather than mobility in a novel open field. Such changes in the information encoded by individual hippocampal neurons in an aversive environment could underlie changes in stress vulnerability because of genetic or epigenetic variations in glucocorticoid receptor signaling.
Integrative diagnostic criterion for evaluation of COVID-19 severity and the risk of post-COVID syndrome
Authors: Nesterova I. V. , Atazhakhova M. G. , Matushkina V. A. , Teterin Yu. V. , Gorodin V. N. , Chudilova G. A. 
Published: November 2022

Pathophysiology of severe COVID-19 is characterized by changes in the number, phenotype, and function of neutrophil granulocytes (NG). Among the effector antiviral mechanisms of NG, the neutrophil extracellular traps (NETs) are among the most important features. However, their excessive formation exacerbates inflammation in acute respiratory distress syndrome and contributes to microvascular thrombosis. Their detection and counting may be important in severity grading of COVID-19, for determining correlations with clinical outcome, assessing the risk of developing post-COVID syndrome, and, possibly, for monitoring future targeted therapy. Purpose of our study was to develop a new diagnostic integrative criterion to assess the severity of COVID-19 and the risk of complications in the post-COVID period, including post-COVID signs in peripheral blood. Peripheral blood (PB) samples were studied from 31 patients with acute COVID-19 of moderate (n = 15) and severe degrees (n = 16). Moreover, we observed 52 patients discharged from the hospital after severe COVID-19, with diagnosed post-COVID syndrome (PCS) over the period of 30 to 60 days, and 100 healthy volunteers. The parameters of routine blood counts (MicroCC-20Plus) were evaluated, the leukocyte formula was calculated in PC smears, taking into account the number of formed NETs, and NGs entering pathological apoptosis. Based on the obtained results, an integral diagnostic criterion was calculated using the formula:$$ IDK = \frac{\%\ unchanged\ NG}{\%NET + \%NG\ in\ apoptosis} $$A 8.5-fold decrease in IDK index (p < 0.05) was shown in the cases of moderate-severity course of the disease, and a 30-fold drop was seen in severe cases (p < 0.05) compared with appropriate values in the group of healthy individuals. It was also found that, in 88.5% of patients with PCS after the SARS-CoV-2 infection, no morphologically altered NG were detectable in PB samples. At the same time, in 11.5% of patients with PCS, we found NETs and cells with pathological apoptosis, whereas IDC of NG-PCS was 8 times less than in the comparison group, and did not differ from the parameters of patients with moderate COVID-19 (p > 0.05) thus requiring further dispensary observation of such patients. The data obtained in this study indicate that the developed integrative diagnostic criterion allows us to assess both the severity of COVID-19 over acute period, and the risk of post-COVID syndrome. It should be emphasized that the characteristic changes in NG detected in COVID-19 may be readily identified in PB and consistently monitored by the proposed integral diagnostic criterion. A significant decrease in IDC indicates the persisting hyper-activation of NG and a need for targeted immunotherapy aimed at modulating the NG dysfunction.
PRÁTICAS AUTORREFERIDAS DE ENFERMEIROS SOBRE GERENCIAMENTO DE ANTIMICROBIANOS
Authors: Da Silva Felix Adriana Maria , Valentim Jarina Nathália , Scalon da Costa Perinoti Lívia Cristina , Sanches Couto Daniela , Dos Reis da Paz Beatriz , Moralez de Figueiredo Rosely 
Published: November 2022

Objetivo: investigar as práticas autorreferidas de enfermeiros no Programa de Gerenciamento de Antimicrobianos (PGA). Método: estudo transversal, descritivo realizado no período de março a abril de 2021, com 40 enfermeiros de uma instituição privada de ensino superior da cidade de São Paulo. Os dados foram coletados por meio de instrumento estruturado e analisados por estatística descritiva. Resultados: Dentre as 14 práticas de enfermagem esperadas nos PGA, os participantes referiram aplicar oito (57,1%) frequentemente. Conclusão: os enfermeiros praticam parcialmente as atividades previstas nos PGA. Faz-se necessário avançar na abordagem dessa temática em sessões educacionais e durante a graduação para que as atividades sejam efetivamente incorporados na prática profissional do enfermeiro.
Palavras-chave: Enfermeiro. Antimicrobianos. Programa de Gerenciamento do uso de antimicrobianos. Resistência antimicrobiana.
Prophesying the End of Human Time: Eco-Anxiety and Regress in J. G. Ballard’s Short Fiction
Authors: Oramus Dominika 
Published: November 2022

Despite being written half a century before the term “eco-anxiety” (Gifford and Gifford) was coined, J. G. Ballard’s disaster fictions can be read in the context of the social psychodynamics of climate change. My aim in this article is to demonstrate that in J. G. Ballard’s fiction, climate catastrophes and the devastation of nature cause the characters to realize that the Earth is not going to be able to sustain human life much longer, and their psychological reaction is either subdued anger or strange numbness. In order to do this, I analyze two short stories by Ballard: “Deep End” (1961) and “Low-Flying Aircraft” (1975) and show how their protagonists are affected by the landscape they inhabit: de-populated wastelands whose wildlife is extinct or mutated. I argue that it is their awareness that human civilization on earth is coming to its end that results in the state of mind akin to eco-anxiety. The characters are immersed in their own inner space and in these stories clocks mark not the passage from past to future but a countdown to the end.
Fuzzy Logic Simulations for a Smart Air Conditioning System
Authors: K RAJA , Ramathilagam S 
Published: November 2022

Abstract
The temperature control, fan speed, and other features of the air conditioning system we use every day are all manually automated. Recent air conditioners offer automatic temperature control, variable fan speed, variable compressor speed, and more. However, using a Fully Logic Control System, we have refined it in this study to move automation one step further ahead. We count the number of people in the room using an IR sensor, and the temperature and fan speed are then adjusted accordingly. We estimate the room's size using sonar, and based on this data, we determine the fin's tilt position and maintain fan speed. We determine the inside temperature using an external temperature and humidity sensor. These are the three variables or ways by which we calculate the temperature, fan speed, and fin direction necessary to maintain the desired temperature.
The Effects of Parity on Duration of Exclusive Breastfeeding in Kilimanjaro Region, Tanzania – A Prospective Cohort Study
Authors: George Johnston Mukiza , Mgongo Melina , Rie Annelies Van 
Published: November 2022

Abstract
Background:Breastfeeding is essential for a child’s healthy growth and development. The World Health Organization recommends early inhiation and six months of continuation of exclusive breastfeeding (EBF). Parity might influence EBF uptake, but it remains unclear how previous breastfeeding duration affects subsequent children's breastfeeding duration among multiparous women.
Methods: Secondary data analysis of a prospective cohort of pregnant women (third trimester) and their infant (followed until age 12 months) enrolled from 2002-2015 in Kilimanjaro-Tanzania. In this analysis, eligible mothers were multipara women who entered the study as primigravida. To evaluate how parity affects EBF duration, Kaplan-Meier survival curves and multivariate Cox-proportional hazard models were applied.
Results: Only 56.3% of children-initiated breastfeeding within one hour of birth. Early initiation of breastfeeding did not differ between firstborn and subsequent-born children (p=0.88) and did not change over time. While 69% of women practiced EBF for three months, only 5% did so for 6 months. The proportion of children receiving EBF for the recommended 6 months rose from 3.2% for firstborns to 5.1% for second-borns, 9.6%, for third-borns and 15.8% for fifth-borns. The mean EBF duration increased from 11.1 weeks in 2000/2005 to 15.0 weeks in 2011/2015, corresponding to 87% higher hazards for longer EBF (aHR: 1.87 95%CI: 1.32-2.63) for children born between 2011 and 2015 compared to those born between 2000 and 2005. Children born to mothers with medium and high SES had 31% (aHR: 1.31 95%CI: 1.10-1.56) and 23% (aHR:1.23 95%CI: 1.00-1.54) higher hazards for prolonged EBF compared to children born to mothers with low SES. Compared to those women who delivered at home, children delivered in health facilities had 22% greater hazards for longer EBF (aHR: 1.22 95%CI: 1.01-1.52).
Conclusion: In this study in Tanzania, an unacceptable low proportion of women completed 6 months EBF, but parity was not independently associated with EBF duration for multiparous women. The increase in EBF duration between 2000 and 2015 shows that EBF is responsive to policy changes and public health efforts. EBF counselling should be improved, especially for women of poor SES and women who deliver at home.
LCK Facilitates DNA Damage Repair by Stabilizing RAD51 and BRCA1 in the Nucleus of Chemoresistant Ovarian Cancer
Authors: Reizes Ofer , DEY GOUTAM , BHARTI RASHMI , Braley Chad , Alluri Ravi , Esakov Emily , Crean-Tate Katie , McCrae Keith , Joehlin-Price Amy , Rose Peter , Lathia Justin , Gong Zihua 
Published: November 2022

Abstract
Poly-ADP Ribose Polymerase (PARP) targeted therapy is clinically approved for the treatment of homologous recombination (HR) repair deficient tumors. The remarkable success of this therapy in the treatment of HR repair deficient cancers has not translated to HR-proficient cancers. Our studies identify the novel role of non-receptor lymphocyte-specific protein tyrosine kinase (LCK) in the regulation of HR repair in endometrioid epithelial ovarian cancer (eEOC) model. We show that DNA damage leads to direct interaction of LCK with the HR repair proteins RAD51 and BRCA1 in a kinase dependent manner RAD51 and BRCA1 stabilization. LCK expression is induced and activated in the nucleus in response to DNA damage insult. Disruption of LCK expression attenuates RAD51, BRCA1, and BRCA2 protein expression by hampering there stability and results in inhibition of HR-mediated DNA repair including suppression of RAD51 foci formation, and augmentation of gH2AX foci formation. In contrast LCK overexpression leads to increased RAD51 and BRCA1 expression with a concomitant increase in HR DNA damage repair. Importantly, attenuation of LCK sensitizes HR-proficient eEOC cells to PARP inhibitor in cells and pre-clinical mouse studies. Collectively, our findings identify a novel therapeutic strategy to expand the utility of PARP targeted therapy in HR proficient ovarian cancer.
Morpho-physiological responses of peppermint (Mentha x piperita L.) by seaweed floair under salinity stress
Authors: Hakimzadeh Mohammad Ali , koshkenow hamideh jafarzade , sodaeizadeh hamid , Esfandiari Motahareh 
Published: November 2022

Abstract
seaweed has developed as a cure with the capability to spare the biological system, because of its eco-friendliness, reasonableness, accessibility, and active ion expulsion rate. This work summarizes the result of saltiness on the organ of plants, and this biomass is revered because the driving redress material among the accessible materials too grandstand the bio activity part of seaweed extricate disengage and its adequacy as a valuable, on morphological and physiological characteristics of peppermint underneath completely different irrigation water salinity was conducted a factorial experiment supported a totally irregular style with four replications within the Yazd University greenhouse in 2020. Experimental factors included salinity stress at four levels of (0, 2, 4 and 8 dS/m) and, seaweed powder application at four levels of (0, 1, 2 and 4 ppt ). Morphological traits or growth parameters and physiological characteristics (relative water content, photosynthetic pigments, total soluble carbohydrate, proline amino acid) assessed. our results demonstrated that seaweed led to changes in peppermint growth and physiology which improved the plant salt stress response. Examination of interaction effects showed was a significant effect on total chlorophyll, chlorophyll a, chlorophyll b, carotenoids (Photosynthetic pigment) and, total soluble carbohydrate at the level of 1% (p≤0.01), and in examining morphological traits results demonstrated that fresh and dry weight of leaves, aerial components, total fresh and dry biomass and harvest index were significant at the level of 1% (p≤0.01). The use of seaweed at 4 ppt under stress-free conditions resulted in the highest weight of leaves, aerial, and total biomass. The highest relative water content was related to the without salinity stress (65.8%). The highest proline content was obtained at 4 and 8 dS/m salinity levels, which showed a rise of 37.5% compared to the management treatment. In general, the results showed that the employment of 2 and 4 ppt seaweed at high levels of salinity (4 and 8 dS/m) reduced the adverse effects of salinity stress by improved physiological traits, together with chemical change pigments and amino acid content. This analysis grandstands the bio activity part of seaweed growth biomass and its adequacy as a helpful, cheap, and reasonable.
Historical and Futuristic Perspectives on Seismic Site Effects in Turkiye-Izmir-Bayrakli Basin
Authors: Cetin Kemal Onder , Cakir Elife , Zarzour Moutassem 
Published: November 2022

Abstract

Due to the unique soil, morphological and subsurface topographical conditions, site effect-induced amplified and prolonged seismic demand traces were observed in historical strong ground motion records from Bayrakli-Izmir-Turkiye. A vivid example of these was documented after the recent October 30, 2020 normal event with Mw 7.0, which took place offshore of Samos Island and Seferihisar. During the event, structural damage and life losses were unexpectedly concentrated in Bayrakli-Izmir, even though the fault rupture was located 70 km away. The presence of strong ground motion stations located on rock and soil sites in Bayrakli enables quantitative assessment of this rather unique response. For this purpose, earthquake records starting from year 2010 till present were compiled and studied to assess intensity- or better to refer as strain- dependent Bayrakli basin-specific, nonlinear amplification factors. 1-D total stress-based equivalent linear site response assessments were performed to better understand and model these effects. Additionally, amplification factors were probabilistically estimated by following the modified analytical procedures. After having calibrated and validated the idealized 1-D models, they were used to predict the responses of the site during future, deterministic, more of design basis like scenario events. The results revealed that the 2475- year design basis spectral amplitudes for a ZE type site could be exceeded in Bayrakli by as much as 20 to 100% in the period range 1.5 to 3.5 seconds. Similarly, the amplification factors by Turkish earthquake code (TEC 2018) are expected to be exceeded under deterministic seismic scenarios on Izmir, Karaburun and Seferihisar faults, with Eurocode (2004) and NEHRP (2020) recommendations to be no exceptions. These clearly address the need to develop Bayrakli-specific seismic zonation and design practices due to its rather unique site effect-governed seismic response.
A bacterial formula with native strains as alternative to chemical fertiliser for tomato crop
Authors: Paganin Patrizia , Isca Clelia , Tasso Flavia , Calandrelli Tommaso , Migliore Giada , Medas Daniela , Dore Elisabetta , Marras Pier Andrea , De Giudici Giovanni , Sprocati Anna Rosa , Alisi Chiara 
Published: November 2022

Abstract
Worldwide productivity of tomato is threatened by biotic and abiotic stress factors. To sustain and guarantee an adequate yield of tomato crops, agricultural practices have been based on the intensive use of fertilisers with negative impacts on the environment. An eco-friendly and sustainable alternative to the traditional cultivation methods is the bioaugmentation approach, using tailor-made microbial consortia. Eight indigenous strains, isolated from the soil of “Terra-Sole” farm in the coastal plain of Pula (Sardinia - Italy), were selected in the laboratory for their plant growth promoting (PGP) functions. The beneficial effects of the bacterial formula, including genera Delftia, Pseudomonas, Paenarthrobacter, Phyllobacterium, Bacillus, and Acinetobacter, were tested in three subsequent field trials carried out at the company greenhouse, with different tomato varieties (Camone, Oblungo, Cherry). The results indicate that the inoculation of the indigenous bacterial formula repeated at the different stages of plant growth, regardless of the tomato variety, represents an effective strategy to obtain a fruit yield comparable to that obtained with chemical fertilisers. The application of proper biofertilisation could thus substitute the use of expensive and polluting chemicals without compromising the tomato yield.