bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk factors for low back pain after oblique lumbar interbody fusion in patients with low-grade degenerative lumbar spondylolisthesis: a retrospective study
Authors: Wang Shuanchi , Chen Jiabao , Lu Zhe 
Published: January 2025

ObjectiveTo investigate the risk factors of low back pain after oblique lumbar interbody fusion (OLIF) in patients with low grade degenerative lumbar spondylolisthesis (DLS).MethodsThis retrospective study included 116 patients with single-level low-grade lumbar spondylolisthesis with low back pain who underwent OLIF surgery in our hospital from December 2017 to October 2020. Demographic, clinical, surgical, and radiological characteristics of this population were analyzed to determine the relationship between these characteristics and the degree of low back pain relief after OLIF.ResultsA total of 116 patients (average age 58.61 ± 7.01 years) were included in this study. Among them, 33 patients had poor improvement of low back pain after surgery, and 83 patients had satisfactory effect after surgery with obvious relief of low back pain. Postoperative disc height increase ≤2.5 mm (P = 0.000) was most correlated with poor improvement of low back pain symptoms after OLIF. The factors positively correlated with poor improvement of low back pain symptoms after OLIF in patients with low-grade degenerative lumbar spondylolisthesis included the increase of spondylolisthesis grade (OR = 17.665; 95%CI: 3.262–95.678 P = 0.001), disc height increase ≤2.5 mm (OR = 34.377; 95%CI: 5.632–209.818 P = 0.000). The factors negatively correlated with poor improvement of low back pain symptoms after OLIF in patients with low-grade degenerative lumbar spondylolisthesis included no osteoporosis (OR = 0.067; 95%CI: 0.013–0.350 P = 0.001), no cage subsidence (OR = 0.208; 95%CI: 0.048–0.903 P = 0.036), duration of preoperative low back pain symptoms ≤36 months (OR = 0.045; 95%CI: 0.007–0.277 P = 0.001).ConclusionsOLIF can significantly improve the low back pain symptoms in patients with low-grade degenerative lumbar spondylolisthesis. High grade of spondylolisthesis before operation, duration of low back pain symptoms more than 36 months, osteoporosis, postoperative cage subsidence, and postoperative segmental disc height improvement less than 2.5 mm are risk factors for low back pain after operation.
Physicochemical profiles of mixed ruminal microbes in response to surface tension and specific surface area
Authors: Liu Yong , Liao Junrui , Tang Shaoxun , Zhou Chuanshe , Tan Zhiliang , Salem Abdelfattah Z. M. 
Published: January 2025

IntroductionIn ruminants, a symbiotic rumen microbiota is responsible for supporting the digestion of dietary fiber and contributes to health traits closely associated with meat and milk quality. A holistic view of the physicochemical profiles of mixed rumen microbiota (MRM) is not well-illustrated.MethodsThe experiment was performed with a 3 × 4 factorial arrangement of the specific surface area (SSA: 3.37, 3.73, and 4.44 m2/g) of NDF extracted from rice straw and the surface tension (ST: 54, 46, 43, and 36 dyn/cm) of a fermented medium in a fermentation time series of 6, 12, 24, 48 h with three experimental units. Here, we used three rumen-fistulated adult Liuyang black goats as the rumen liquid donors for this experiment.ResultsIt was found that increasing SSA decreased the average acetate/propionate ratio (A/P, p &lt; 0.05) and increased the molarity of propionate (p &lt; 0.05). Increasing ST decreased total volatile fatty acid (tVFA) concentration (p &lt; 0.01). Greater SSA increased (p &lt; 0.01) MRM hydrophobicity, whereas increasing ST increased MRM cell membrane permeability (p &lt; 0.01). The neutral detergent fiber digestibility (NDFD, r = 0.937) and tVFA (r = 0.809) were positively correlated with the membrane permeability of MRM.DiscussionThe surface tension of the artificial medium and substrate-specific surface area had a significant influence on MRM's fermentation profiles, hydrophobicity, and permeability. The results suggest that physical environmental properties are key in regulating rumen fermentation function and homeostasis in the gastrointestinal tract ecosystem.
Fusobacterium nucleatum and Treponema denticola are robust biomarkers for gingivitis and periodontitis in small dogs
Authors: Kwon Daehyun , Bae Kisuk , Jang Kwangsik , Jo Hyun Min , Kang Seong Soo , Byun Jonghoe , Kim Se Eun 
Published: January 2025

IntroductionPeriodontal disease is one of the most common oral diseases in dogs and humans. It starts with gingivitis, a reversible condition, and progresses to an irreversible condition, periodontitis. Unlike humans, the etiology of periodontal disease in dogs has not been widely studied. Many studies suggest that bacteria strongly implicated in human periodontal disease might also play a role in canine periodontal disease. In contrast to studies examining only the prevalence of bacteria, a recent study analyzed 336 gingival crevicular fluid (GCF) samples in dogs to evaluate the prevalence of 11 putative periodontopathic bacteria and the correlation and association of bacterial numbers individually and in combination with periodontal disease stages. Results showed that Treponema denticola (Td) was a strong prognostic biomarker for periodontitis in dogs. However, a limitation of this study was that samples were grouped according to the periodontal status of the target tooth only, without assessment of the overall oral health. Furthermore, the findings of this study revealed a need for validation in a larger sample size.Materials and methodsThis study ensured that the overall oral health assessment of dogs under 20 kg matched with sampled groups, thus eliminating the influence of environmental factors on the results. Furthermore, 1,054 GCF samples were analyzed using quantitative real-time polymerase chain reaction (qPCR) for 12 bacteria, including the same 11 putative periodontopathic bacteria [Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg), Tannerella forsythia (Tf), Td, Fusobacterium nucleatum (Fn), Prevotella nigrescens (Pn), Prevotella intermedia (Pi), Parvimonas micra (Pm), Eubacterium nodatum (En), Campylobacter rectus (Cr), and Eikenella corrodens (Ec)] and Porphyromonas gulae (P. gulae), suspected to be a major causative agent of periodontitis in dogs in some statistical evaluatioins.ResultsInterestingly, the present study found that Fn was strongly associated with gingivitis and reconfirmed a strong association between Td and periodontitis (irreversible periodontal disease). However, Aa showed no relevance, and P. gulae was not significantly associated with periodontal disease in dogs in this study.ConclusionThese findings suggest that Fn and Td would be robust biomarkers for the severity of periodontal disease in small dogs.
Pain as a Symptom of Mental Health Conditions Among Undocumented Migrants in France: Results From a Cross-Sectional Study
Authors: Moussaoui Sohela , Vignier Nicolas , Guillaume Stephanie , Jusot Florence , Marsaudon Antoine , Wittwer Jérôme , Dourgnon Paul 
Published: January 2025

ObjectivesThis study aimed to explore the associations between mental health status and experienced pain among undocumented migrants (UMs) in France.MethodsWe used data from the multicentric cross-sectional “Premier Pas” study conducted in the Parisian and Bordeaux regions from February to April 2019. Participants over 18 years of age were recruited from sixty-three sites. Pain was assessed through two variables: overall pain and musculoskeletal pain. Mental health conditions, including anxiety, sleep disorders, depression, and posttraumatic stress disorder (PTSD) were evaluated. Logistic regression models were used to explore associations, controlling for social determinants of health (SDHs).ResultsOur findings revealed significant associations between mental health status and pain among the 1,188 included participants. Sleep disorder was associated to higher odds of musculoskeletal pain (aOR = 2.53, 95% CI [1.20–5.33], p = 0.014). Stratified results indicated that among women, depression was associated to higher odds of pain (aOR = 4.85, 95% CI [1.53–13.36], p = 0.007).ConclusionThis large study confirms the connection between mental health status and pain among UMs, providing valuable evidence for clinicians to address mental health issues in this population.
Delays in Blood Work and Disease Burden: A Cross-Sectional Analysis of Unmet Blood Work Need and Seven Key Health Conditions Across 21 Countries
Authors: Chung Eunice , Ewald Louisa , Kassembaum Nicholas J. , Noyes Taylor , Gakidou Emmanuela , Mokdad Ali H. 
Published: January 2025

ObjectivesThis study analyzes survey data across 21 countries to explore correlations between delays in blood testing and the prevalence of seven health conditions: thalassaemias, sickle cell disorders, malaria, HIV, high fasting plasma glucose, impaired kidney function, and high LDL cholesterol.MethodsWe analyzed Pandemic Recovery Survey data via multivariable logistic regression to compare blood test delays between individuals with and without medical conditions, while adjusting for sociodemographic factors. We also examined the disease burden using disability-adjusted life years (DALYs) and summary exposure values (SEV) rates.ResultsOur findings indicate profound disparities, with over 60% of respondents in Egypt, Nigeria, and India reporting they have never undergone blood tests. Individuals with existing medical conditions are significantly more likely to experience delays in blood work.ConclusionThere is a pronounced gap in blood work accessibility, particularly in countries with high disease burdens. Findings suggest an urgent need for interventions to improve routine blood test access for high-risk populations to reduce the underdiagnosis of significant medical conditions. Prioritizing timely and accessible blood testing can serve as a step towards mitigating healthcare disparities.
Rendimiento en canal y calidad sensorial de la carne del pocoyo (Dormitator latifrons) en policultivo con la tilapia azul (Oreochromis aureus)
Authors: Valverde-Moya José , Montero Álvaro 
Published: January 2025

Dormitator latifrons ha demostrado ser una especie con gran potencial acuícola para cultivo, pero debido al desconocimiento de su gastronomía a nivel nacional, hasta la fecha no tiene demanda ni valor de mercado a pesar de la opinión de la excelente calidad organoléptica de su carne en otros países. En este estudio, se evalúo el rendimiento de la carne en canal de D. latifrons sexado y el grado de aceptación sensorial que tienen los consumidores sobre la calidad de este pescado proveniente de un sistema tradicional de cultivo. Con el análisis sensorial se logran conocer las propiedades organolépticas de un alimento por medio de los sentidos para tener un juicio más objetivo acerca de este. El peso promedio entero en la muestra evaluada fue de 185,8 ± 42,6 para las hembras y 170,0 ± 27,3 para los machos. El peso en la canal fue similar para ambos sexos con rendimientos de 75 ± 5% para las hembras y 79 ± 2% para los machos, con un porcentaje de las vísceras de 23 ± 5% y 19 ± 3%, respectivamente. El análisis sensorial se evaluó mediante una prueba hedónica encuestando a 20 personas. A más del 70% de los encuestados les gustó la jugosidad (79%) y el sabor (73%) de D. latifrons cultivado y en todos los criterios analizados, el sabor obtuvo la mayor aceptación (60% gustó mucho y 13% gustó). El olor obtuvo la aceptación más baja (33%) seguido por la textura (28%). Estas características sensoriales se relacionaron con el sistema de producción implementado. El buen rendimiento en la canal y la gran aceptación en el sabor, hacen que D. latifrons sea una especie nativa promisoria para el cultivo comercial y la venta en el mercado local y nacional en este tipo de presentación.
Estrategia didáctica: La gamificación para fomentar la lectura comprensiva de los estudiantes de primero de bachillerato
Authors: Salina Briones Deysi Betzabeth , Cevallos Sánchez Herman Arnulfo 
Published: January 2025

La lectura implica un conjunto de habilidades que ponen a prueba las capacidades y conocimiento de los alumnos, incidiendo en la subjetivación de estos para construcción de criterios propios. La gamificación motiva y enriquece este proceso de aprendizaje a través del juego, haciendo uso de la tecnología como recurso didáctico para crear un espacio interactivo e inmersivo. Este estudio se desarrolló en la Unidad Educativa Paulo Emilio Macias en Portoviejo con el objetivo de diseñar una estrategia didáctica para el uso de la gamificación en el aprendizaje de la lectura comprensiva empleando para ello el paradigma pragmático con enfoque mixto, no experimental, descriptivo; y, en abordaje cualitativo el método de Investigación Acción Participativa. En el artículo, se divulgan los resultados cuantitativos en dos momentos, uno inicial o prediagnóstico para identificar el nivel de comprensión lectora y otro posterior a la aplicación de la estrategia didáctica con el propósito de medir su impacto, y; de la misma manera, se describe el proceso cualitativo que condujo la investigación, provocando la propuesta gamificada. Se aplicó el test ACL- 5 con 35 ítems a 89 estudiantes de primer año de Bachillerato. Los resultados cuantitativos demostraron que los estudiantes aumentaron su nivel de compresión lectora una vez gamificada esta actividad. Se concluye que la gamificación es una herramienta inherente para el desarrollo del aprendizaje, siendo necesario que los docentes manejen esta temática, especialmente para mejorar el análisis de lectura en los estudiantes)
PALABRAS CLAVE: Compresión lectora; gamificación; educación; aprendizaje; estrategia didáctica.
KAJI EKSPERIMENTAL PENGARUH CAMPURAN BIOETANOL DARI MOLASSE PADA BAHAN BAKAR GASOLINE TERHADAP EMISI GAS BUANG YANG DIHASILKAN
Authors: Risky Muhammad , Drajat Indah Mawarni*  
Published: January 2025

Bioethanol is an alcohol compound that comes from the fermentation process of carbohydrate compounds using the help of the microbe saccaromyches cereviceae. Bioethanol production from plants containing cellulose, including molasses, is carried out through the conversion process of lignocellulose into cellulose using several methods, namely; physical, chemical and biological hydrolysis. Molasses which comes from the Gendis Multi Manis Jepon Blora Sugar Factory, Central Java, is a by-product of the sugar processing industry which still contains sugar and organic acids. The molasses produced has a fairly high sucrose content in molasses, around 48-55% so it can be used as a good raw material for making ethanol. The results of tests carried out using a mixture of Bioethanol with Pertalite fuel have an influence on exhaust gas emissions by increasing the bioethanol mixture. produces different values ​​of CO, HC, CO2, O2. The highest CO value in pure pertalite fuel is 7.79% and the lowest CO value is in the 30% Bioethanol mixture, namely with a CO value of 0.27%. The highest HC value in pure pertalite fuel is 7.31 ppm and the HC value the lowest was in the 10% Bioethanol mixture, namely 1.52 ppm. The highest CO2 value was in the 30% Bioethanol mixture, namely 9.00% and the lowest CO2 value was in the 10% Bioethanol mixture, namely with a CO2 value of 2.30%. Furthermore, the highest O2 value was in the 30% Bioethanol mixture, namely 14.46% and the lowest O2 value was in the 10% Bioethanol mixture, namely with an O2 value of 3.46%.
ANALISIS PREDIKSI KELULUSAN MAHASISWA DENGAN METODE NAIVE BAYES CLASSIFIER
Authors: Masungging Dwi Cahyo  , Sri Redjek  , Erna Hudianti Pujiarini  
Published: January 2025

Kelulusan dalam waktu yang ditetapkan merupakan salah satu indikator keberhasilan mahasiswa dan kualitas Perguruan tinggi. Prediksi kelulusan tepat waktu perlu dilakukan guna meningkatkan efesiensi sistem pendidikan pada Perguruan Tinggi. Metode Naive Bayes Classifier merupakan metode klasifikasi yang dapat digunakan memprediksi mahasiswa akan lulus tepat waktu atau tidak. Metode Naive Bayes Classifier didasarkan pada teorema Bayes dengan asumsi independensi antar fitur. Data penelitian yang digunakan sebanyak 247 mahasiswa telah lulus. Atribut yang digunakan meliputi jenis kelamin, asal daerah, Indeks Prestasi Semester (IPS) 1 hingga 4, dan nilai mata kuliah kompetensi dengan variabel target empat kategori. Untuk data latih diambil sebanyak 197 (80%) sedangkan data uji diambil sebanyak 50 (20%). Hasil penelitian menunjukkan bahwa model Naive Bayes Classifier memiliki akurasi yang tinggi dalam memprediksi kelulusan mahasiswa, yaitu sebesar 94%. Nilai presisi model untuk kategori 1 dan kategori 3, masing-masing mencapai 94% dan 100% sedangkan presisi model untuk kategori 2 dan kategori 4 adalah 0. Nilai recall untuk kategori 1 dan kategori 3 mencapai 100% sedangkan untuk kategori 2 dan kategori 4 adalah 0. Nilai F1-Score menunjukkan keseimbangan yang cukup baik antara presisi dan recall, yaitu sebesar 49%.
PENGUSIR BURUNG PINTAR BERBASIS INTERNET OF THINGS (IoT)
Authors: Gatot Santoso  , Suwanto Raharjo  , Slamet Hani  , Faidzus Rohman  
Published: January 2025

Penelitian ini bertujuan untuk merancang sistem otomasi pengusir burung pintar berbasis Internet of Things (IoT). yang dirancang untuk pertanian pintar di Desa Pandan. Sistem ini menggunakan modul ESP32 sebagai pengendali utama, yang dipasangkan dengan sensor ultrasonik untuk mendeteksi burung hama, serta termasuk buzzer dan motor servo untuk mengusir burung tersebut. Sistem ini dikendalikan melalui aplikasi Blynk, memungkinkan pengoperasian manual dan otomatis dari jarak jauh menggunakan smartphone. Proses perancangan alat mencakup pembuatan skematik rangkaian dan desain wiring diagram yang diterapkan dalam bentuk modul fisik. Hasil pemrograman ESP32 berhasil diupload dan diuji, memastikan alat beroperasi sesuai dengan pengaturan yang telah ditetapkan. Pengujian dilakukan untuk mengukur kinerja sensor ultrasonik, keaktifan buzzer dan servo, serta efektivitas kontrol manual dan virtual melalui aplikasi Blynk. Pengujian jarak kontrol manual beroprasi dengan baik dan deley rata-rata berada di 1,55 detik – 1,59 detik yang di peroleh hanya selisish sedikit hanya karena diakibatkan oleh sinyal dari smartphone. Pada data sheet sensor ultrasonik komponen dapat mendeteksi objek hingga jarak 5 meter tetapi sensor ultrasonik sistem ini efektif mendeteksi objek dalam jangkauan 3 meter, dan buzzer serta servo berfungsi sesuai harapan. Kontrol melalui Blynk bekerja dengan baik selama perangkat terhubung ke Wi-Fi. Penelitian ini menyimpulkan bahwa sistem otomasi pengusir hama burung berbasis IoT dapat diterapkan dengan baik untuk mendukung smart farming.
ФАКТОРЫ РИСКА У ПОДРОСТКОВ С ОЖИРЕНИЕМ И МЕТАБОЛИЧЕСКИМИ ИЗМЕНЕНИЯМИ В ГЕНДЕРНОМ АСПЕКТЕ
Authors: Балашова А.Д. 
Published: January 2025

Несмотря на огромное количество исследований, посвященных изучению проблемы ожирения, на сегодняшний день является открытым вопрос факторов риска развития данного заболевания, а также зачастую сопутствующих ему компонентов метаболического синдрома. Целью данного исследования являлось изучение факторов риска развития ожирения с метаболическим синдромом у пациентов подросткового возраста, в том числе в гендерном аспекте. В работе рассмотрели роль перинатальных факторов, наследственности, особенностей пищевого поведения, психологического статуса и микросоциума. В статье показано, что неблагоприятные перинатальные факторы, проблемы раннего грудного периода жизни, а также отягощенную наследственность по кардиоваскулярной и эндокринной патологии имели все подростки с ожирением, независимо от наличия компонентов метаболического синдрома и половой принадлежности. Также у всех обследованных подростков имели место нежелательные особенности пищевого статуса в сочетании с гиподинамией, но чаще они встречались у девушек с ожирением и метаболическими изменениями. Кроме того, психологические проблемы, в том числе семейные превалировали у исследованной группы подростков, также у женского пола. Учитывая, важность выявленных факторов, целесообразно их включение при разработке персонифицированных лечебно-реабилитационных программ реабилитации для пациентов с ожирением.
Despite the huge amount of research studying the problem of obesity, today the question of risk factors for the development of this disease, as well as the often-accompanying metabolic syndrome components, is open. The purpose of this study was to study risk factors for the development of obesity with metabolic syndrome among adolescent patients, including their gender. The work examines the role of perinatal factors, heredity, eating behavior, psychological status and microsociety. The article shows that all obese adolescents had unfavorable perinatal factors, problems of the early infancy period, as well as a family history of cardiovascular and endocrine pathologies, regardless of the presence of metabolic syndrome components and gender. Also all the examined adolescents had undesirable features of nutritional status in combination with physical inactivity, but they were more common in girls with obesity and metabolic changes. In addition, psychological problems including family ones also prevailed in the studied group of adolescent females. Considering the importance of the identified factors, it is advisable to include them in the development of personalized treatment and rehabilitation programs for patients with obesity.
МНОЖЕСТВЕННЫЕ ОЧАГИ ОСТЕОНЕКРОЗА У ПАЦИЕНТА С ГЕРМИНОМОЙ ЦЕНТРАЛЬНОЙ НЕРВНОЙ СИСТЕМЫ
Authors: Харчиков Д.В. , Бондаренко В.П. , Чурикова А.И. , Карелин А.Ф. , Терещенко Г.В. 
Published: January 2025

Лечение злокачественных новообразований сопровождается развитием, так называемых поздних токсических эффектов. Авторы представили клинический случай развития очагов остеонекроза у пациента с герминомой центральной нервной системы. Клинический случай. Пациент М. 16 лет получил комплексную противоопухолевую терапию, в результате лечения злокачественного новообразования у пациента развились множественные эндокринные нарушения, в том числе с появлением асептических очагов остеонекроза различной локализации на фоне остеопении. Обсуждение. Лечение злокачественных новообразований в детском возрасте может привести к развитию остеопении/остеопороза— состояния, вызванного нарушением минеральной плотности кости, что сопровождается снижением доли кроветворного костного мозга, увеличением содержания адипоцитов и снижением количества остеобластов, остеоцитов. Заключение. Развитие остеонекроза в описанном клиническом случае представляет собой многофакторный процесс, обусловленный, вероятно, исходным опухолевым процессом, химио- и лучевой терапией, синергическим действием кортикостероидов, применяемых в рамках гормональной заместительной терапии гипокортицизма, метаболических и обменных нарушений на фоне эндокринных осложнений лечения герминомы.
Treatment of malignant neoplasms is accompanied by the development of so-called late toxic effects. The authors presented a clinical case of the development of osteonecrosis in a patient with a germinoma of the central nervous system. Clinical case. Patient M., 16 years old, received complex antitumor therapy; as a result of treatment of a malignant neoplasm, the patient developed multiple endocrine disorders, including the appearance of aseptic foci of osteonecrosis of various locations against the background of osteopenia. Discussion. Treatment of malignant neoplasms in childhood can lead to the development of osteopenia/osteoporosis - a condition caused by a violation of bone mineral density, which is accompanied by a decrease in the proportion of hematopoietic bone marrow, an increase in the content of adipocytes and a decrease in the number of osteoblasts and osteocytes. Conclusion. The development of osteonecrosis in the described clinical case is a multifactorial process, probably caused by the initial tumor process, chemotherapy and radiation therapy, the synergistic effect of corticosteroids used as part of hormonal replacement therapy for hypocortisolism, metabolic and metabolic disorders against the background of endocrine complications of germinoma treatment.