bluuebunny/crossref_metadata_2025_split huggingface dataset:
The specificity of methods of online teaching to play the piano for students of primary, secondary and senior classes of music schools
Authors: Чжоу Е. 
Published: October 2022

Представлены некоторые методы онлайн-обучения игре на фортепиано. Детально рассмотрена специфика методов онлайн-обучения музыке в разных возрастных группах. Отмечена важность максимального приближения онлайн-обучения к очному формату, необходимость сохранения индивидуального подхода к каждому ученику.
The article represents some methods of online learning to play the piano. The specifics of online music teaching methods in different age groups are represented in detail. In the article noted the importance of bringing online learning as close as possible to the usual format, the need to maintain an individual approach to each student.
Ocular Findings in Rheumatoid Arthritis: Retrospective Study
Authors: ÇETİNKAYA Yasemin Fatma 
Published: October 2022

Objective: The aim of this study is to determine the accompanying ocular findings, frequency and to examine the complications in Rheumatoid Arthritis (RA) patients.
Method: Medical records of Rheumatoid Arthritis patients who were consulted with the eye clinic between 2017 and 2022, were retrospectively reviewed. Demographic features, eye examination findings, and detected eye diseases were noted.
Results: The records of 23840 Rheumatoid Arthritis and related patients who were consulted with the Eye Clinic were reviewed. From these patient records, 2691 patients, who were especially diagnosed with seropositive Rheumatoid Arthritis, were evaluated in detail within the scope of the study. Ophthalmological examination findings obtained from the records were examined. In particular, anterior segment biomicroscopy, Schirmer test, tear break-up time (BUT) and fundus examination was evaluated. 2067 of the patients were female and 624 were male. And the mean age was examined. When the average age is examined; patients aged 41-65 years were the most common (1795 patients (1374 women, 421 men)). The most common sign of ocular involvement was a dry eye(%25.97). Less frequently, episcleritis was found in 4.57% of patients, and scleritis was found in 1.37%. There were no patients with posterior or necrotizing scleritis among the patients examined. In addition, posterior scleritis of the cornea, scleromalacia, or retinal vasculitis were not detected in our patients.
Conclusion: Rheumatoid Arthritis is a disease that can progress with extra-articular findings and may even appear as the first finding. Ocular findings may accompany the disease at a considerable rate. It can also affect the prognosis of the disease with the right perspective.
De cómo un conflicto parroquial influyó en los debates sobre la laicidad argentina: la destitución del cura de San Cristóbal en 1886 y sus inesperadas derivaciones
Authors: Di Stefano Roberto 
Published: October 2022

En la historia argentina, la década de 1880 es célebre por los debates públicos en torno a la definición de la laicidad. En ese decenio se discutieron y promulgaron tres proyectos legislativos que se cristalizaron en las «leyes laicas» de educación, registro civil y matrimonio civil. En 1886, un conflicto aparentemente baladí entre un párroco de los suburbios de Buenos Aires y el arzobispo potenció un enfrentamiento que alcanzó las más altas esferas políticas y eclesiásticas, concitó la atención de personajes públicos de primera línea y hasta dio lugar a la adopción de medidas legislativas relevantes. La historia de ese episodio es interesante porque puso sobre el tapete temas cruciales que hacían a la definición de la laicidad y porque muestra el peso que un hecho fortuito, en principio intrascendente, puede adquirir en la toma de decisiones al más alto nivel, ilustra las intrincadas relaciones que median entre acontecimientos, coyunturas y transformaciones estructurales y nos habla de los vínculos dialécticos entre los discursos y sus contextos de enunciación.
La implementación de las políticas públicas adoptadas por el Estado peruano frente al impacto del COVID-19 en la violencia contra las mujeres e intrafamiliar
Authors: Huaita Alegre Marcela , Hancco Rodríguez Norely 
Published: October 2022

En el presente artículo, las autoras analizan la respuesta del Estado peruano a través de la implementación de diversas políticas públicas con el objetivo de contrarrestar la violencia contra las mujeres e integrantes del grupo familiar fortalecida y desencadenada por el contexto de la pandemia del COVID-19.
Primero, las autoras estudian las medidas tomadas de manera inmediata por el Estado peruano durante el inicio de la pandemia y las sitúan en el contexto latinoamericano mediante una perspectiva comparada. En un segundo momento, tales medidas se analizan con el fin de hacer un balance entre los límites y logros en su implementación efectiva durante el primer año de la pandemia.
Vacuna contra el COVID-19: ¿el ordenamiento jurídico peruano permite su aplicación obligatoria?
Authors: Valero Quispe Christian Dennis 
Published: October 2022

El sector salud no fue el único afectado por la pandemia producto del COVID-19, la rápida propagación de este virus impactó en la educación, la economía, el trabajo, el turismo, entre otros sectores. Esta situación conllevó a que diversos laboratorios farmacéuticos de todo el mundo inicien una investigación para desarrollar una vacuna. Como resultado de estas investigaciones, a nivel internacional, en pleno 2020, se llevó a cabo un proceso de vacunación; por su parte, en el Perú se inició con este proceso a inicios de 2021.
En el presente artículo, el autor analiza si el ordenamiento jurídico peruano permite la aplicación obligatoria de la vacuna contra el COVID-19, para ello se realizó una ponderación de derechos entre la libertad individual de quienes no desean vacunarse y la salud pública. Adicionalmente, se sostiene que una medida como restringir el acceso a espacios cerrados debe considerar los principios de razonabilidad y proporcionalidad. De este modo, se concluye que no es posible someter a un tratamiento médico a una persona que no haya expresado su consentimiento; sin embargo, sí existe la posibilidad de imponer restricciones como prohibir el acceso a medios de transporte o el ingreso a universidades a las personas que no estén vacunadas.
Designing an Android-based mobile app to address issues with online shopping
Authors: Salama Ramiz , Arab Duaa Abu 
Published: October 2022

Recently, most companies have develop mobile applications since phones are the main way to use the Internet rather than computers. Based on the evidence, the year 2021 witnessed a huge increase in the number of online purchases, especially during the corona pandemic and other diseases that emerged after it. This research, therefore, aimed to develop a mobile application that can provide ease of shopping and help its users to take advantage of discount prices across their region, especially during the COVID-19 lockdown. ‘Discount Guide’ was a great solution during this time and forever. This application is designed to allow the seller and the buyer as well to sell or buy discounted items. This app was built using the Java language, Android studio, Gradle and JUI to design the app effectively and more easily. As a result, the customer gets the benefit from using the app for online shopping on their Android devices.

Keywords: Android, application, mobile, MySQL, online shopping, smartphone;
Pemodelan faktor-faktor yang memengaruhi angka kesembuhan tuberkulosis di Jawa Barat menggunakan regresi spline truncated
Authors: Evitasari Niken , Handajani Sri Sulistijowati , Pratiwi Hasih 
Published: October 2022

Tuberculosis is a bacterial infection caused by Mycobacterium tuberculosis. Transmission of tuberculosis (TBC) can occur due to environmental factors and community behavior. West Java is Indonesia's province with the highest number of tuberculosis cases. Curing tuberculosis is critical to reducing cases and breaking the transmission chain. The Human Development Index (IPM), good sanitation, comprehensive tuberculosis treatment, public spaces (PS) meeting health criteria, and residents having health insurance are all assumed to influence the tuberculosis cure rate. This research aimed to model the elements that have a substantial impact on tuberculosis cure rates.The tuberculosis cure rate in West Java in 2020 was modeled using nonparametric spline truncated linear regression with a combination of knot points (3,3,3,3,2). The lowest Generalized Cross Validation (GCV) value of 26.7579 was used to find the best knot point. The adjusted coefficient of determination for this study was 96.35 percent, indicating that the linear truncated spline regression model with a combination of knot points is feasible to use in modeling. The five predictor variables simultaneously affect the tuberculosis cure rate of 96.35 percent, while 3.65 percent is influenced by other variables not used in the study.
Keywords: Spline truncated, tuberculosis cure, knots, GCVMSC2020: 62G08
Variasi spasial dan temporal nilai-b pada gempa bumi di wilayah Sulawesi Tengah, Gorontalo, dan sekitarnya menggunakan metode robust fitting
Authors: Fitriyati Nina , Wijaya Madona Yunita , Bisyri M. Alvi 
Published: October 2022

This study discusses variation in seismic and tectonic modeled by a Gutenberg-Richter relationship for earthquakes in the Central Sulawesi, Gorontalo, and surrounding areas using the Robust Fitting Method (RFM) with the weight function of Tukey’s bisquare. The declustering process on earthquake data is carried out using the Reasenberg equation. The values for both parameters are analyzed spatially and temporally. In the spatial analysis, the research area is divided into 43 grids. In the temporal analysis, the research area is divided into zone A and zone B. The data grouping is done using a sliding time window method, i.e., grouping 50 earthquake catalogs with 5 overlapping events. The results according to spatial analysis show that the b-values range from 0.38 – 1.19. Areas with low b-values (0.38 – 0.7) occur around the Palu-Koro Fault, i.e., Palu city, Malacca strait, and to Toli-Toli, and also in the northern region of Gorontalo, i.e., the subduction plate of the Sulawesi Sea. Meanwhile, high b-values (0.71 – 1.19) are in the Tomini Bay area which is an area with frequent occurrence of earthquakes but has the small potential to generate large-scale earthquakes. The results of the temporal b-value estimation in zones A and B range between values of 0.38 - 1.25. The b-values appear to decrease before the occurrence of major earthquakes in 1996 and 2018 in zone A. The b-values decreased before the occurrence of major earthquakes in 1990, 1991, 2000, and 2008 in zone B. However, the b-values cannot be used as a precursor before the big earthquake in 1997.
Keywords: Tukey’s bisquare, Reasenberg equation, Gutenberg-Richter relationship, sliding time window, Robust Fitting Method. MSC2020: 86A15
Role of Nintedanib in COVID-19-Related Lung Fibrosis
Authors: Fathurrachman Alif , Andriani Linda , Pasaribu Rouly , Sudarto Sudarto , Rasyid Ahmad , Ahmad Zen , Setiawan Tommy 
Published: October 2022

In December 2020, Indonesia was introduced to the long Coronavirus disease 2019 (COVID-19) phenomenon. The Centers for Disease Control and Prevention (CDC) introduced the term "post-COVID condition" as a health problem that persists after four weeks from the first exposure to COVID-19. The National Institute for Healthcare and Care Excellence (NICE) classifies COVID-19 infections into three categories based on disease duration: (1) acute infection for up to 4 weeks; (2) ongoing infection within 4-12 weeks; and (3) post-COVID-19 syndrome for more than 12 weeks and not associated with an alternative diagnosis. One of these phenomena is lung fibrosis. About 80% of COVID-19 survivors had mild to severe chest X-rays in 6 months of follow-up with decreasing lung function. COVID-19-related lung fibrosis is still not widely researched. COVID-19 survivors who develop lung fibrosis usually recover independently, but some develop persistent lung fibrosis. The use of antifibrotic agents, such as nintedanib, has long been approved for idiopathic pulmonary fibrosis (IPF). However, its use in the cases of lung fibrosis due to COVID-19 has not been widely studied. Nintedanib is a tyrosine kinase inhibitor. It inhibits receptor activity of vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and fibroblast growth factor (FGF). Those actions will eventually inhibit the proliferation, migration, and transformation of fibroblasts into myofibroblasts in lung fibrogenesis. Therefore, an antifibrotic agent is potentially needed to inhibit COVID-19-related lung fibrosis to improve quality of life and prevent further lung damage.
Understanding Text and Context for Productive Reading: an Analysis of Abu Zaid’s Hermeneutics of the Qur’an
Authors: Kasim Muhammad Yusuf , Haddade Hasyim 
Published: October 2022

<p align="left">This paper describes the thoughts of Nasr Hamid Abu Zaid on the theory of Al-Qur’an interpretation, with a descriptive-analytic analysis. The data were collected from various sources from Nasr’s writings, books, and journals that wrote about Nasr and his thoughts, as well as other sources that had relevance for analysis purposes. Abu Zaid tries to reveal the meaning and significance (<em>magza</em>) which then brings out the meaning of “the ineffable”. In this case, the meaning is represented by the text or in the sense that it lets the text speak about itself. Then, from that meaning, there is a dialogue with the conditions or contexts that surround a reader. Therefore, the meaning is static because it contains historical meaning, and the significance is dynamic in accordance with the horizon of each reader. </p>
Growing Pacific linkage with western North Atlantic explosive cyclogenesis
Authors: Stuivenvolt-Allen Jacob , Wang Simon S.-Y. , Chikamoto Yoshimitsu , Meyer Jonathan D.D. , Johnson Zachary F. , Deng Liping 
Published: October 2022

Abstract
Explosive cyclones (ECs), defined as developing extratropical cyclones that experience pressure drops of at least 24 hPa in 24 hours, are impactful weather events which occur along highly populated coastal regions in the eastern United States. These storms occur due to a combination of atmospheric and surface processes, such as jet stream intensification and latent heat release. Even though previous literature has elucidated the role of these processes in EC formation, the sources of interannual variability that impact seasonal EC frequency are not well known. To analyze the sources of interannual variability, we track cases of ECs and dissect them into two spatial groups: those that formed near the east coast of North America (coastal) and those in the North Central Atlantic (high latitude). The frequency of high-latitude ECs is strongly correlated with the North Atlantic Oscillation, a well-known feature, whereas coastal EC frequency exhibits a growing relationship with an atmospheric wave-train emanating from the North Pacific in the last 30 years. This wave-train pattern of alternating high-and-low pressure resulted in heightened upper-level divergence and baroclinic instability along the east coast of North America. Using a coupled model experiment, we show that the tropical Pacific Ocean and North Pacific oceans are the main driver of this atmospheric wave train and the subsequent enhancement seasonal baroclinic instability in the North Atlantic.
Application of Zinc Oxide Reduces the Bioavailability and Specific Uptake of Cadmium by Alfalfa Grown in a Cadmium-contaminated Alkaline Soil
Authors: He Honghua , Zhang Zekun , Wu Miaomiao 
Published: October 2022

Abstract
Zinc (Zn) and cadmium (Cd) have similar chemical properties and interact with each other in the soil-plant system. Application of Zn may be an effective way for phytoremediation of Cd-contaminated soils. A greenhouse pot experiment was carried out to grow alfalfa in an alkaline soil spiked with Cd (0, 20, and 80 mg kg–1) and Zn (0, 200, and 800 mg kg–1) as cadmium oxide (CdO) and zinc oxide (ZnO), respectively, to investigate the effects of ZnO application on soil Cd bioavailability, plant growth and Cd uptake. Adding ZnO resulted in a lower soil pH and greater DTPA-extractable Zn concentration, but a lower DTPA-extractable Cd concentration. The effect of ZnO addition on Cd bioavailability depended on both soil Cd level and Zn dose. Soil Cd contamination considerably inhibited plant growth and increased both root and shoot Cd concentrations. Adding ZnO significantly enhanced plant growth, reduced Cd uptake per unit root dry mass and plant Cd concentrations, but did not affect the total amount of Cd taken up by plants. The percentage of total plant Cd content allocated to roots was significantly lower, but the root-to-shoot translocation factor of Cd was higher when ZnO was added. Both CdO and ZnO addition had a small effect on root exudation of carboxylates. Application of ZnO to soil alleviated Zn deficiency and reduced Cd bioavailability, consequently enhanced plant growth and Cd concentrations, and it may be an effective way for phytoremediation of Cd-contaminated soils.
Development of a new 3D tracking system for multiple marmosets under free-moving conditions
Authors: Yurimoto Terumi , Kumita Wakako , Sato Kenya , Kikuchi Rika , Shibuki Yusuke , Hashimoto Rino , Kamioka Michiko , Hayasegawa Yumi , Yamazaki Eiko , Kurotaki Yoko , Goda Norio , Kitakami Junichi , Fujita Tatsuya , Inoue Takashi , Sasaki Erika 
Published: October 2022

Abstract
Accurate assessment of behavioral changes and social interactions in mammalian models is necessary to elucidate the pathogenesis of neurological disorders. The common marmoset (Callithrix jacchus) is a useful model in this regard. However, behavioral measurements, including assessments of sociality of free-moving group animals, have not been conducted in marmosets. Here, we developed a new behavioral analysis system for three-dimensional (3D) trajectories of independently free-moving multiple individuals by combining video tracking, 3D coordinates detected using light detection and ranging (Lidar), and facial recognition. Each marmoset was identified using deep learning facial recognition (accuracy ≥ 97%). Location preferences and distances between individuals were calculated using 3D trajectories, and grooming was detected using deep learning. This system will allow quantification of individual captive group animals, facilitating automatic measurement of social behavior. Furthermore, the behavioral changes observed might be directly extrapolated to humans and contribute to better understanding of the mechanisms underlying neurodegenerative disorders.
Effects of sodium para-aminosalicylic acid on chelation treatment in Pb-exposed mice
Authors: Li Yan , Liang Yuan , Fang Yuan-yuan , Chen Jing , Zheng Xiao-wei , Zhou Wu-wang , Lu Li-li , Aschner Michael , Ou Shi-yan , Jiang Yue-ming 
Published: October 2022

Abstract
Lead (Pb) is a corrosion-resistant, heavy, non-ferrous metal with widespread environmental pollution. Several metal chelators have been used in the treatment of Pb poisoning. However, the effect of sodium para-aminosalicylic acid(PAS-Na)on Pb excretion has yet to be reported. To investigate the effects of PAS-Na on Pb excretion, a mouse model of acute lead exposure was established. Healthy mice (90) received abdominal injection (i.p.) of 120 mg/kg Pb acetate, and 4 h later 80, 160, 240 mg/kg PAS-Na, or 240 mg/kg edetate calcium disodium (CaNa2EDTA) were injected subcutaneously (s.c.) once per day for 6 days into the corresponding groups, respectively. The Control, Pb-exposed, PAS-Na and CaNa2EDTA groups were evaluated simultaneously. After collecting 24 h urine samples, the animals were sacrificed in batches on the 2nd, 4th, 6th day. Levels of Pb and other metal elements [including manganese (Mn) and copper (Cu)] in the urine, whole blood and brain tissues were analyzed by graphite furnace atomic absorption spectrometry (AAS). The results showed that lead exposure increased Pb levels in urine and blood of mice, and PAS-Na treatment afforded antagonistic effect against Pb-induced toxicity. While additional studies will be needed, these novel results establish PAS-Na as a potential efficacious treatment for mitigating Pb-induced toxicity.
Transcriptional alteration in NF-κB-associated long noncoding RNAs in the gastric tissue of the Helicobacter pylori infected and non-infected patients with chronic gastritis
Authors: Ghanbarian Marzieh , Bakhtiari Ronak , Mirbagheri Seyedeh Zohre , Rezaei Fatemeh , Foroushani Abbas Rahimi , Alebouyeh Masoud 
Published: October 2022

Abstract
Background: Helicobacter pylori could colonize the gastric mucosa and cause gastritis, gastric ulcer and gastric cancer. Numerous virulence factors have been identified in this bacterium that play important roles in the promotion of gastric disorders. Although the interaction of long noncoding RNAs (lncRNAs) with transcription, processing, and translation of genes associated with different diseases are described, their interaction with the inflammatory genes and H. pylori infection in the gastric tissue is not well known. In this study, H. pylori infection and its effect on the transcription of common lncRNAs that regulate NF-κB expression were analyzed relative to the non-infected patients.
Materials and Methods: Two groups of H. pylori-infected and non-infected patients with chronic gastritis were included in the study after general histopathological and microbiological analysis. Genotyping of the H. pylori strains was done by PCR and relative changes in the expression of NF-κB and regulatory lncRNAs, lincRNA-p21, MALAT1, NKILA, were measured by relative quantitative real time-PCR.
Results: Significant increase in the NF-κB gene expression was shown, while the expression level of MALAT1, lincRNA-p21 and NKILA genes decreased in the infected patients compared with the non-infected patients. Our results showed that the hypervirulent strain with oipA“on”/HP-NAP+/iceA1+/iceA2+/vacA s1m1/s1m2+/cagA+ genotype can promote a higher level of NF-κB transcription in the inflamed tissue.
Conclusion: H. pylori infection could promote down-regulation of lincRNA-p21, MALAT1 and NKILA in the infected gastric tissue that is correlated with upregulation of NF-κB. More detailed studies are needed to show link between the virulence genes and their impact on the deregulation of lncRNAs in the gastric tissue.