bluuebunny/crossref_metadata_2025_split huggingface dataset:
COVID-19, business continuity management and standardization: case study of Huawei
Authors: Chen Shumei , Xu Jia 
Published: September 2022

PurposeThis paper aims to theoretically and empirically demonstrate the role played by business continuity management (BCM) to address risks such as trade conflicts and natural disasters. This paper also answers whether compliance with international standards such as the International Organization for Standardization (ISO) 22301 is adequate.Design/methodology/approachA case study of Chinese telecommunications giant Huawei is conducted to examine how a robust end-to-end BCM system has been established in two decades and in what way it has helped Huawei to efficiently maintain growth under pressure, such as being added to the “Entity List” and the pandemic.FindingsHuawei case contributes to BCM theory in its approach to establishing the BCM system and its well-established BCM model. Huawei establishes and continually improves its BCM system by applying the Plan (establish), Do (implement and operate), Check (monitor and review) and Act (maintain and improve) cycle. Characterized as 4Ps: BCM policy, BCM process, incident management plan and business continuity plan, Huawei BCM system is shaped into a loop with end-to-end BCM process, covering all steps along its value chain – from suppliers and partners to Huawei itself and then on to its customers – with key initiatives for all domains such as R&D, procurement, manufacturing, logistics and global technical services. In practice, implementing international standards such as ISO 22301 enables Huawei to develop business continuity but not enough. Optimizing the BCM system is an ongoing effort, and BCM maturity is ever present: continually improving Huawei’s own BCM system and benchmarking against best practices available worldwide.Research limitations/implicationsApart from the case study, other methods such as counter-factual analysis can be used to further test whether Huawei’s BCM system is cost-effective. Another direction for future study is whether suggested BCM maturity levels should be supplemented into ISO 22301. In the digital age, how to use digitalization to ensure business continuity is a current issue not just for practitioners such as Huawei but also for researchers worldwide.Practical implicationsIn practice, implementing international standards such as ISO 22301 enables Huawei to develop business continuity but not enough. Optimizing the BCM system is an ongoing effort, and BCM maturity is ever present: continually improving Huawei’s own BCM system and benchmarking against best practices available worldwide.Originality/valueTo the best of the authors’ knowledge, this is one of the first studies to focus on how an organization continually improves the suitability, adequacy and effectiveness of its BCM system, with special attention to standards compliance.
Packaging-integrated-products: capturing new opportunities in the front end of product development
Authors: Simms Chris , Trott Paul 
Published: September 2022

Purpose
The purpose of this paper is to examine how firms manage the front end of new product development projects where packaging forms a core part of the product itself. Within the fast-moving consumer goods industry, innovation provides opportunities to create packaging that forms an integrated part of the product offering. The authors refer to these as packaging-integrated-products. This study conceptualises three levels of integration and investigates how they impact upon the management of the front end.

Design/methodology/approach
The study consisted of a two-phase design. This involved a preliminary study with key informants, followed by a multiple case study design, which examines product development projects with differing extents of packaging integration.

Findings
The results identify nine different new product opportunities. The authors also present 11 propositions that reveal the key characteristics of the front end of packaging-integrated development projects, as well as the project management requirements to capture the opportunities they present.

Research limitations/implications
Initial insights into a number of unique front-end project management characteristics required to deliver different project types form an area for further research to better understand product packaging integration. The propositions presented guide the way forward for future studies.

Practical implications
The findings provide marketers with new understanding of three types of new product opportunities presented by packaging integration and demonstrate what is required to capture the opportunities they present in the front end of product development.

Originality/value
The paper contributes to extant studies of packaging development in the marketing literature, which have previously failed to capture the high levels of integration between packaging and the product. The authors present a new conceptual approach to understanding integration and subsequently uncover how the opportunities it presents can be captured.
Marketing in a crisis: lessons from the “COVID election” in New Zealand
Authors: Elder Edward , Lees-Marshment Jennifer , Bendle Neil Thomas 
Published: September 2022

PurposeThis paper aims to identify both the traditional and novel forms of marketing behind New Zealand Prime Minster Jacinda Ardern’s landslide victory in the 2020 New Zealand General Election during the COVID-19 pandemic.Design/methodology/approachThis research analysed both qualitative and quantitative data, including over 70 primary sources, the perspectives of practitioners, polling and data from surveys with over 450,000 respondents. The qualitative data was analysed interpretively against established theoretical concepts, whereas the quantitative data was analysed through descriptive statistics.FindingsThis research found that COVID-19 drastically changed what the public prioritised, allowing Ardern and Labour to position themselves as guardians of government stability, while camouflaging previous delivery failures. Labour also used a more emergent market-oriented and “polite” populist political marketing strategy.Research limitations/implicationsWhile the survey data used is not a perfect sample of the population, it is the largest public opinion survey in New Zealand and, given its convergence with other sources, provides valuable insights into political marketing during a crisis more broadly.Practical implicationsThis research reinforces marketing’s most important aspect; the market should drive action. How decision makers respond to the market should depend on the environment. Thus, up-to-date market research becomes even more important during a crisis, as the environment changes rapidly. This leaves prior assumptions obsolete and implies strategy needs to be adaptive. Additionally, greater public attention provides governing leaders with the opportunity to present a more well-rounded leadership image.Originality/valueTo the best of the authors’ knowledge, this is the first research to look at marketing while in government and election campaigning in the context of successful management of a global pandemic.
The link between transformational leadership and organizational development: testing the mediating role of employees' maturity
Authors: Radi Afsouran Naghi , Charkhabi Morteza , Mohammadkhani Fatemeh , Seidel Laura 
Published: September 2022

PurposeThis study aims to test the association between transformational leadership and its components and organizational development. As a second aim, this study examines the extent to which employees' maturity may mediate the link between transformational leadership and organizational development.Design/methodology/approachHypotheses were tested on a sample of 248 full-time employees (58% men, 42% women) recruited by a simple random sampling method from four Iranian public organizations. Participants were asked to complete scales on transformational leadership, organizational development, and employees' maturity.FindingsPearson correlation analysis showed a positively significant association between transformational leadership and organizational development. Furthermore, path analysis of structural equation modeling revealed that the direct effect of transformational leadership on organizational development is significant. Additionally, the analysis supported the mediating role of employees' maturity in the link between transformational leadership and organizational development.Originality/valueTransformational leaders may use the maturity of employees to increase their impact in the process of organizational development.
Male rock hyraxes that maintain an isochronous song rhythm achieve higher reproductive success
Authors: Demartsev Vlad , Haddas‐Sasson Michal , Ilany Amiyaal , Koren Lee , Geffen Eli 
Published: September 2022

Abstract

Rhythmic stability (nonrandom temporal structure) is required for many neural and physiological functions, whereas rhythmic irregularities can indicate genetic or developmental deficiencies. Therefore, rhythmic courtship or contest signals are widespread in nature as honest advertisement displays. Examination of bird songs revealed the pervasiveness of categorical rhythmic patterns that can be described as small integer ratios between sequential inter‐call intervals. As similar rhythmic profiles are prevalent in human music, it was suggested that a shared functionality could drive both animal songs and human musical rhythms, facilitating synchrony between signallers and enabling easy identification of performance errors.

Here we examined whether the rhythmic structure and the rhythmic stability of vocal displays are related to reproductive success in male rock hyraxes (Procavia capensis), which presents an unusual case of a terrestrial singing mammal.

We combined long‐term parentage analysis of 13 male hyraxes (22 male/years) with an analysis of an audio library of 105 hyrax songs. Male annual reproductive success was determined by the number of offspring that survived to the age of 1 year. The frequency of singing events was used to determine the seasonal singing effort for each male. Songs were analysed for rhythmic structure, focusing on the presence of categorical rhythms and the contribution of rhythmic stability to annual reproductive success.

We found that male hyraxes that sing more frequently tend to have more surviving offspring and that the rhythmic profile of hyrax songs is predominantly isochronous with sequential vocal element pairs nearly equally spaced. The ratio of isochronous vocal element transitions (on‐integer) to element transitions that deviate from an isochronous pattern (off‐integer) in hyrax songs is positively correlated with male reproductive success.

Our findings support the notion that isochronous rhythmic stability can serve as an indication of quality in sexually selected signals and is not necessarily driven by the need for multiple caller synchronization. The relative scarcity of nonisochronous rhythmic categories in individually performed hyrax songs raises the question of whether such rhythmic categories could be a product of collective, coordinated signalling, while being selected against in individual performance.
On the role of hypotheses in science
Authors: Brüssow Harald 
Published: September 2022

AbstractScientific research progresses by the dialectic dialogue between hypothesis building and the experimental testing of these hypotheses. Microbiologists as biologists in general can rely on an increasing set of sophisticated experimental methods for hypothesis testing such that many scientists maintain that progress in biology essentially comes with new experimental tools. While this is certainly true, the importance of hypothesis building in science should not be neglected. Some scientists rely on intuition for hypothesis building. However, there is also a large body of philosophical thinking on hypothesis building whose knowledge may be of use to young scientists. The present essay presents a primer into philosophical thoughts on hypothesis building and illustrates it with two hypotheses that played a major role in the history of science (the parallel axiom and the fifth element hypothesis). It continues with philosophical concepts on hypotheses as a calculus that fits observations (Copernicus), the need for plausibility (Descartes and Gilbert) and for explicatory power imposing a strong selection on theories (Darwin, James and Dewey). Galilei introduced and James and Poincaré later justified the reductionist principle in hypothesis building. Waddington stressed the feed‐forward aspect of fruitful hypothesis building, while Poincaré called for a dialogue between experiment and hypothesis and distinguished false, true, fruitful and dangerous hypotheses. Theoretical biology plays a much lesser role than theoretical physics because physical thinking strives for unification principle across the universe while biology is confronted with a breathtaking diversity of life forms and its historical development on a single planet. Knowledge of the philosophical foundations on hypothesis building in science might stimulate more hypothesis‐driven experimentation that simple observation‐oriented “fishing expeditions” in biological research.
Vector redesign and in‐droplet cell‐growth improves enrichment and recovery in live Escherichia coli
Authors: Eenink Bernard D. G. , Kaminski Tomasz S. , Bornberg‐Bauer Erich , Jose Joachim , Hollfelder Florian , van Loo Bert 
Published: September 2022

AbstractDirected evolution (DE) is a widely used method for improving the function of biomolecules via multiple rounds of mutation and selection. Microfluidic droplets have emerged as an important means to screen the large libraries needed for DE, but this approach was so far partially limited by the need to lyse cells, recover DNA, and retransform into cells for the next round, necessitating the use of a high‐copy number plasmid or oversampling. The recently developed live cell recovery avoids some of these limitations by directly regrowing selected cells after sorting. However, repeated sorting cycles used to further enrich the most active variants ultimately resulted in unfavourable recovery of empty plasmid vector‐containing cells over those expressing the protein of interest. In this study, we found that engineering of the original expression vector solved the problem of false positives (i.e. plasmids lacking an insert) cells containing empty vectors. Five approaches to measure activity of cell‐displayed enzymes in microdroplets were compared. By comparing various cell treatment methods prior to droplet sorting two things were found. Substrate encapsulation from the start, that is prior to expression of enzyme, showed no disadvantage to post‐induction substrate addition by pico‐injection with respect to recovery of true positive variants. Furthermore in‐droplet cell growth prior to induction of enzyme production improves the total amount of cells retrieved (recovery) and proportion of true positive variants (enrichment) after droplet sorting.
A case of multiple primary lung adenocarcinoma with a CD74‐NRG1 fusion protein and HER2 mutation benefit from combined target therapy
Authors: Chen Kai , Li Wen , Xi Xiaoming , Zhong Jia 
Published: September 2022

AbstractNeuregulin 1 (NRG1) gene fusion is a rare oncogenic driver gene in multiple tumor types, leading to the activation of the epidermal growth factor receptor (ErbB)‐mediated pathway. Therefore, afatinib, a pan‐ErbB family inhibitor, may be a therapeutic candidate for NRG1 fusion‐driven tumors. In this case, we report a multiple primary lung adenocarcinoma patient harboring the CD74‐NRG1 fusion, epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 2 (ERBB2) mutation simultaneously. The patient received afatinib and pyrotinib combination therapy and showed a significant treatment response with a progression‐free survival of 5 months. Our case further supports the use of targeted therapy for NRG1 fusion‐positive non‐small‐cell lung cancer.
Incidence‐data‐based species richness estimation via a Beta‐Binomial model
Authors: Chiu Chun‐Huo 
Published: September 2022

Abstract

Individual‐based abundance data and sample‐based incidence data are the two most widely used survey data formats to assess the species diversity in a target area, where the sample‐based incidence data are more available and efficient for estimating species richness. For species individual with spatial aggregation, individual‐unit‐based random sampling scheme is difficult to implement, and quadrat‐unit‐based sampling scheme is more available to implement and more likely to fit the model assumption of random sampling. In addition, sample‐based incidence data, without recording the number of individuals of a species and only recording the binary presence or absence of a species in the sampled unit, could considerably reduce the survey loading in the field.

In this study, according to sample‐based incidence data and based on a beta‐binomial model assumption, instead of using the maximum likelihood method, I used the moment method to derive the richness estimator. The proposed richness estimation method provides a lower bound estimator of species richness for beta‐binomial models, in which the new method only uses the number of singletons, doubletons and tripletons in the sample to estimate undetected richness.

I evaluated the proposed estimator using simulated datasets generated from various species abundance models. For highly heterogeneous communities, the simulation results indicate that the proposed estimator could provide a more stable, less biased estimate and a more accurate 95% confidence interval of true richness compared to other traditional parametric‐based estimators.

I also applied the proposed approach to real datasets for assessment and comparison with traditional estimators. The newly proposed richness estimator provides different information and conclusions from other estimators.
Development of the motivational thought frequency scale for alcohol abstinence (MTF‐A)
Authors: Cheng Brandon , Coates Jason M. , Gullo Matthew J. , Chan Gary , Kavanagh David J. , Feeney Gerald F. X. , Young Ross Mc D. , Clark Paul J. , Connor Jason P. 
Published: September 2022

AbstractBackground and aimsFor most treatment‐seeking patients with severe Alcohol Use Disorder (AUD), abstinence is the clinically indicated goal. Existing AUD motivation scales are non‐specific about treatment consumption goals, which limit their effectiveness. Desires and mental imagery are relevant in the motivation for AUD treatment engagement. The Motivational Thought Frequency Scale for an abstinence goal (MTF‐A) was adapted from the MTF for controlled drinking (MTF‐CD). This study psychometrically evaluated the MTF‐A in an alcohol‐dependent sample engaged in treatment with a goal of abstinence. To enhance the clinical utility of the scale, a secondary aim was to evaluate a psychometrically equivalent short version of the MTF‐A.MethodA sample N of 329 treatment‐seeking patients with AUD (mean age of 44.44 years, SD = 11.89 years, 72% male) who were undertaking a cognitive behavioral treatment (CBT) program for abstinence completed the Motivational Thought Frequency Scale for Abstinence (MTF‐A) and the Severity of Alcohol Dependence Questionnaire (SADQ). The MTF‐A measured motivation for abstinence through four factors: intensity, self‐efficacy imagery, incentives imagery, and availability. Confirmatory factor analyses (CFAs) were conducted to examine factor structure and model fit. Cronbach's alpha assessed internal consistency. Predictive validity was determined by logistic regression predicting first‐session treatment non‐attendance and alcohol consumption between baseline assessment and commencement of treatment, controlling for potential confounds.ResultsA four‐factor structure provided the best fit for the MTF‐A, compared with one‐ and three‐factor models. A shortened 9‐item MTF‐A scale (S‐MTF‐A) provided better fit than the 13‐item MTF‐A scale. Both MTF‐A and S‐MTF‐A displayed good internal consistency. Although both MTF‐A and S‐MTF‐A successfully predicted first‐session treatment non‐attendance, neither predicted alcohol consumption between the baseline assessment and commencement of treatment.ConclusionsThe model fit of the four‐factor, 9‐item S‐MTF‐A was superior to the original 13‐item MTF‐A. Both scales were predictive of participation of AUD treatment. Desires and mental imagery play an important role in AUD treatment motivation.
Reflections on working and walking gently together in collaboration and partnership in Aboriginal ageing research
Authors: Wall Sharon , Donovan Terrence , Radford Kylie , Allan Wendy , Daylight Gail , Finlay Ellen 
Published: September 2022

AbstractProblemAn important aspect of the work that takes place in and across our Aboriginal Health and Ageing research group is about building partnerships between Aboriginal and Torres Strait Islander peoples and non‐Indigenous people. Partnerships are created between colleagues and co‐researchers as well as with community Elders, Aboriginal community‐controlled organisations, community groups and associations and individuals.SettingTo fully realise this has required an introspective look at the way we function as a team of Aboriginal researchers and non‐Indigenous researchers working together. It has challenged us to explore and determine our shared visions and shared outcomes and to develop strong, enduring and authentic partnerships by putting culture at the centre of everything we do.Key measures for improvementThis wisdom‐led approach has fostered the development of a shared narrative about research WITH Aboriginal and Torres Strait Islander communities and a shared language of research collaboration.Strategies and effects of changeThis paper aims to provide an opportunity to reflect on the key elements of co‐design which have underpinned our work together across cultures both within team and within community.Lessons learntThis paper will provide lived examples of the co‐design and co‐creation process utilised by our team in working with community. It will further share a model which underpins these experiences. It provides a framework to refer to and reflect upon, which commits to working with shared respect, shared meaning, shared knowledge and an enriched experience of collaboratively working and walking and learning together.