bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANTIBACTERIAL THERAPY IN INFECTED FORMS OF NECROTIC PANCREATITIS
Authors: Goldovskiy B. M. , Medvedev V. P. , Filimonova I. V. , Miheev Yu. O. , Lelyuk D. V. , Paketa A. I. , Litvinenko V. V. 
Published: June 2022

Summary: Evaluation of the effectiveness of antibacterial therapy at different stages of necrotic pancreatitis (NP) is the most important area of ​​scientific and practical research on the course of necrotic pancreatitis and the development of sepsis. The work is based on the results of a comprehensive examination and treatment of 54 patients with necrotic pancreatitis in the intensive care unit of city Hospital № 3, Zaporizhia in 2017-2019 pp.
Objective: Optimize the use of antibacterial therapy in the complex treatment of infected forms of NP depending on the microbial spectrum of infection, the course of the disease and the development of sepsis.
Material and methods of research. The study included 54 patients with infected forms of NP who were treated in the Department of Anesthesiology and Intensive Care of the 3rd City Hospital. Research results and their discussion. Thus, the analysis of antibiotic sensitivity showed that high activity against pathogens, based on the perception of the main pathogens characteristic of infected forms of NP, is observed in meropenem, taigecycline and tobramycin. When studying the species composition of microorganisms, it was found that the NP is dominated by gram-negative flora: Pseudomonas aeruginosa - 26.5%, Acinetobacter spp. - 21.2%, family Enterobacteriaceae: Klebsiella pneumoniae - 10.2% and Escherichia coli - 15.6%. Resistant strains of Ps were found in 22% of patients. Aeruginosa. The use of detoxification therapy with the inclusion of extracorporeal detoxification methods (discrete plasmapheresis) in combination with two-component antibacterial therapy (meropenem + linezolid) led to a positive trend in the course of the disease.
Conclusions. Analyzing the course of the disease in patients with infected NP and its complications on the basis of constant monitoring of bacterial flora with optimal antibacterial therapy, prevention of nosocomial infection and modern strategy of surgical interventions, especially minimally invasive, noted a positive trend in the course of sepsis and sepsis.
Diagnostic capabilities of optical coherence tomography and optical coherence tomography angiography in the diagnosis of primary open-angle glaucoma
Authors: Lutsenko N. S. , Nedilka T. V. 
Published: June 2022

Abstract. to assess the features of the retinal nerve fiber layer (RNFL), ganglion complex (GC) and the microcirculatory bed of the retina in patients with primary open-angle glaucoma (POAG) using optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA).
Materials and methods: The study involved 20 people (11 females, 9 males). Patients were divided into 2 groups. The first group included 10 clinically healthy individuals, the second group - 10 patients with POAG. All patients underwent standard ophthalmic examination, OCT / OCTA examination of the RNFL, GC and retinal microcirculatory bed.
Results: The study identified the most sensitive indicators to the progression of the glaucoma process. It was found that the RNFL thickness and the density of the retinal vascular progressively decrease with the development of glaucoma opticopathy. Compared with the group of healthy individuals in patients with POAG, the RNFL thickness in the lower temporal sector of the peripapillary zone was reduced by 44.04% (p <0,01). Compared with healthy individuals, the density of the superficial vascular plexus decreased by 16.3%, deep - by 12.5% ​​(p <0,01). The perimeter of the foveolar avascular zone in patients with glaucoma increased by 31.01%, the area of ​​the foveolar avascular zone increased 1.6 times (p <0.01).
Conclusions: OCT and OCTA are effective methods for assessing the state of GC, RNFL and microcirculatory bed of the retina, which allow for non-invasive monitoring and evaluation of these indicators in patients with POAG.
The use of procalcitonin in patients with pyogenic liver abscesses
Authors: Novak V. V. 
Published: June 2022

The results of treatment of 79 patients with pyogenic liver abscesses (AP) were analyzed. Sepsis was diagnosed in 10 (16.1%) patients. Procalcitonin (PCT) levels were used to diagnose sepsis. The duration of antibacterial therapy (ABT) was based on the determination of PCT and the patient's clinical condition. The decision to prescribe or abstain from ABT should be reviewed within the next 6-24 hours based on the patient's clinical condition and PCT level. These values ​​should also be taken into account in the decision-making process regarding the duration of ABT, as well as the clinical course of the disease. There were no fatalities in the treatment of AP.
Purpose of the study. To determine the diagnostic and prognostic significance of procalcitonin in patients with pyogenic liver abscesses.
Materials and methods. The results of treatment of 79 patients with pyogenic liver abscesses were analyzed. The mean age of patients was 48.4 ± 4.7 years, with men predominating (62.9%). The inclusion criterion was the presence of pyogenic liver abscesses, the exclusion criteria were cholangiogenic and specific abscesses. The main group consisted of 44 patients who received comprehensive conservative therapy, taking into account antibacterial treatment, the duration of which was determined by determining the level of PСT. Patients in the control group (35 patients) did not differ from the main in age, sex, comorbidities, severity of the disease and the results of microbiological examination, but received conventional ABT.
Results. Carrying out adequate combined antibiotic therapy in patients with AP by determining PKT, along with surgery, reduced the recovery time of patients: 2-3 days normalization of body temperature (t = 5.66176; P <0.000001) and leukocyte formula (t = 8,56860; P <0,000001) patients of the main group compared with control patients
Conclusion. Conducting ABT by determining the level of PСT contributed to a probable reduction in the length of stay in the hospital for 3 days (t = 3.95561; P = 0.000116).
EFFICIENCY OF PAIN SYNDROME TREATMENT IN PATIENTS WITH MUSCULOSKELETAL PATHOLOGY IN COMPLEX USE OF SHOCK-WAVE AND HIGH TONE POWER THERAPY
Authors: Alypova O. E. , Dotsenko O. M. , Dotsenko S. Ya. 
Published: June 2022

Purpose of the study. Pain is the main complaint of patients with musculoskeletal pathology, the treatment of which by pharmacological methods has significant side effects. Therefore, non-drug treatment, especially physiotherapy, is increasingly being considered as a first-line treatment option. We evaluated the effectiveness of treatment of pain syndrome in complex use of Shock Wave (SW) and High-Tone Power (HiToP) physiotherapy in patients with musculoskeletal pathology.
Methods. We examined 72 patients (mean age 57.6 ± 0.8 years) with musculoskeletal pathology. The course of SW on the affected area is up to 5-6 procedures with an interval between sessions of 3-7 days. The duration of HiToP therapy ranged from 8 to 10 procedures (3-5 sessions per week). Evaluation of the effectiveness of combined physiotherapy was performed according to the Visual - Analog Scale (VAS) and Short Form Health Survey questionnaire (SF-36).
Results. After a course of combined SW and HiToP physiotherapy all patients with musculoskeletal pathology showed positive dynamics in the pain syndrome. At the same time, according to the visual - analog scale of VAS, there was a significant decrease in pain intensity by an average of 35.8% (p <0.05) compared to baseline before treatment. A probable improvement in the quality of life of patients (SF-36 questionnaire) on the scales of both physical and mental functioning was achieved.
Conclusion. The combined use of SW and HiToP physiotherapy has a positive effect on pain and quality of life in 91.7% of patients with pathology of the musculoskeletal system.
ELECTROCHEMOTHERAPY IN THE TREATMENT OF UNRESECTABLE PANCREATIC CANCER
Authors: Kovalev A. A. 
Published: June 2022

Pancreatic cancer (PC) is a malignant tumor with a poor prognosis and an extremely low 5-year survival rate. No more than 10% of patients have local cancer of the pancreas; in the rest, at the time of the initial diagnosis, it is already a systemic disease. In most patients, relapse occurs within the first 6 months after resection and adjuvant therapy. 95% of patients with prostate cancer require palliative therapy.
For 40 years, the results of treatment of metastatic prostate cancer have improved slightly. Gemcitabine monotherapy increased overall survival to 6 months; combinations of gemcitabine with nab-paclitaxel, liposomal irinotecan with 5-FU, or FOLFIRINOX triplet did not achieve 1-year survival.
To date, the survival limit of patients has been reached, and the likelihood of a radical change in the treatment paradigm over the next five years is very small.
The results of current clinical trials examining the effects of new drugs in prostate cancer can be expected in about 8-10 years, with an estimated success rate of about 3%.
A new method of local tumor ablation, which combines intravenous administration of cytostatics (for example, cisplatin or bleomycin) with exposure of tumor cells to constant currents with extremely short and intense pulses (8 nano-pulses of 100 microseconds duration), is the method of electrochemotherapy (clinical therapy).
Unlike radiofrequency, microwave or laser ablation, in which tissues are destroyed as a result of high temperatures with the formation of a zone of coagulation necrosis, the method of electroporation is not associated with thermal exposure, it is safer and can be used in various clinical situations, including in the treatment of cancer. pancreas.
Dynamic Electro-Amplified Chemotherapy (D-EECT) is a safe, simple and effective clinical method for treating large tumor masses. This method opens up a new direction and creates good prospects in the treatment of inoperable, chemoresistant and radioresistant tumors.
In some studies, the median time to progression (PFS) and overall survival (OS) from the moment of diagnosis in patients with unresectable prostate cancer was 22.8 and 30.7 months, respectively, which clearly exceeds the same indicators when using standard methods of anticancer chemotherapy.
The method of electrochemotherapy using Scandinavian ChemoTech AB equipment has already been registered in Ukraine and will soon improve the treatment of patients with complex tumors of various localizations, including those with unresectable forms of pancreatic cancer.
Clinical Features and Principles of Differential Diagnosis of Erysipelas
Authors: Shapoval S. D. , Vasylevska L. A. , Bielinska V. O. 
Published: June 2022

Purpose. The purpose is to find out the common and different features of the clinical course of erysipelas from other diseases that can imitate it. Materials and methods. 114 case histories of patients who were hospitalized in the center of purulent-septic surgery in the Non-profit municipal enterprise “City Hospital № 3” in Zaporizhzhia for the period 2019-2020 were analyzed. 123 patients, who underwent hospital treatment in the center during this period of time, were with post-injection abscesses of soft tissue, 184 - with soft tissue abscesses, 203 - with phlegmons of various localizations, 49 - with complicated panaritium, 3 of which - subcutaneous. Over the past 5 years, 127 patients were consulted in the clinic and other therapeutic, infectious, neurological and other departments of the city. A number of criteria and signs have been identified to differentiate erysipelas from diseases that may have similar clinical symptoms and a number of circumstances that need to be clarified. Results. It is established that the diagnosis of erysipelas does not require special laboratory examination and is made on the basis of examination of the patient, epidemiological history and medical history. Provoking factors in the development of erysipelas are: violation of the integrity of the skin (abrasions, scratches, abrasions, cracks, bruises, injuries); mycoses; a sharp change in temperature (supercooling, overheating); emotional stress; increased insolation. Erysipelas has a characteristic summer-autumn seasonality. In people engaged in physical labor, the disease is registered more often than in other types of work. Hereditary predisposition to the disease is observed in 10-15% of cases. In this regard, the presence of such factors as congenital and acquired venous insufficiency of the lower extremities, fungal infection of the lower extremities, the presence of postoperative and post-traumatic scars, lymphostasis, diabetes, cardiovascular disease and diseases accompanied by the development of edema, intake of corticosteroids or cytostatics are of essential significance in the development of the disease.
Conclusions. Mathematical modeling between erysipelas and other diseases that have similar syndromes in their clinical picture may be useful in making a differential diagnosis between them.
Perbedaan Tingkat Konsentrasi Belajar Mahasiswa Terhadap Metode Pembelajaran Online dan Offline pada Mahasiswa Fisioterapi STIKES Suaka Insan Banjarmasin
Authors: Sadu Bernadus , Imus Wendelinus , Prayogo Dadan , Wicaksono Utomo , Ahok Martinus 
Published: June 2022

Kegiatan pembelajaran merupakan hal utama didalam dunia pendidikan. Pelaksanaan kegiatan belajar sebelumnya dilaksanakan dengan offline atau tatap muka secara langsung harus diubah dan dilakukan secara during atau online. Hal ini harus dilakukan terkait dengan mewabahnya covid-19 diseluruh dunia termasuk Indonesia. Konsentrasi belajar merupakan kemampuan sesorang dalam menjaga fokus atau perhatiannya untuk tetap tertuju kepada proses pembelajaran yang sedang berlangsung. Tujuan penelitian ini adalah untuk mengetahui perbedaan tingkat konsetrasi belajar mahasiswa fisioterapi Stikes Suaka Insan Banjarmasin saat mengikuti perkuliahan secara online dan offline Penelitian ini merupakan penelitian deskriptif kuantitatif dengan rancangan penelitian cross sectional, dengan subjek penelitian adalah seluruh mahasiswa fisioterapi Stikes Suaka Insan Banjarmasin. Pengumpulan data menggunakan angket (kuesioner) tingkat konsentrasi belajar. Hasil penelitian menunjukan tingkat konsentrasi belajar mahasiswa pada metode pembelajaran online didapatkan rerata nilai 70,16±3,18 termasuk dalam tingkat konsentrasi kategori sedang. Pada metode pembelajaran offline didapatkan nilai rerata 76,08±7,10 termasuk dalam tingkat konsentrasi kategori Tinggi. Kesimpulan yang dapat diambil dari hasil penelitian ini adalah tingkat konsentrasi belajar mahasiswa Stikes Suaka Insan Banjarmasin pada saat mengikuti metode pembelajaran offline lebih baik daripada tingkat konsentrasi belajar mahasiswa saat mengikuti pembelajaran secara online, dengan p-value 0,000.
Peran Virtual Tour sebagai Media Promosi Kunjungan ke Taman Nasional selama Pandemic Covid-19: Kajian Netnografi berdasarkan Komentar Youtube
Authors: Anggraini Ratih 
Published: June 2022

Pada awal Maret 2020 dilaporkan kasus pertama Covid-19 di Indonesia. Setelah pelaporan tersebut, terjadi peningkatan jumlah kasus infeksi dan kematian akibat Virus Corona. Hal tersebut membuat pemerintah melakukan pembatasan kegiatan masyarakat salah satunya adalah dengan melarang bepergian dan berkerumun. Hal ini tentu berdampak negatif terhadap sektor pariwisata. Penelitian ini bertujuan untuk mengkaji peran Youtube dalam mempromosikan Taman Nasional sebagai destinasi wisata di tengah dinamika COVID-19. Dalam penelitian ini, analisis isi menggunakan materi Youtube Ayo ke Taman Nasional sebagai pendekatan kualitatif. Konten tersebut diperoleh series virtual tour ke taman nasional sebanyak 36 video. Analisis data konten Youtube dilakukan dengan menggunakan NVivo 12 Plus. Hasil penelitian menujukkan bahwa durasi rata-rata setiap tayangan virtual tour ke Taman Nasional adalah 114:73±23:37 dengan rata-rata pengunjung adalah sebesar 842,06±777,64. Komentar rata-rata pada konten virtual tour sebesar 2,29±3,25. Jumlah suka rata-rata adalah sebesar 37,63±24,07 dan sama sekali tidak ada pengujung yang menekan tombol tidak suka. Hasil word cloud bahwa kata keren dan mantab sering dipakai dalam komentar untuk menunjukkan apresiasi positif dari peserta. Selain itu juga, komentar didominasi oleh sentimen positif. Komentar positif tersebut menjadi indikator bahwa peserta merasa puas terhadap aktivitas virtual tous. Iimplikasi penelitian ini bisa dimanfaatkan sebagai bagian dari promosi pemasaran dan edukasi terhadap taman nasional yang efektif selama pandemi COVID-19.
MODELING OF CRACK DEVELOPMENT SCHEMES IN SLABS AND SHAPE SHELLS BASED ON TRAJECTORIES OF THE HIGHEST TENSILE STRESSES
Authors: Аверина Т.А. 
Published: June 2022

В статье выполнен расчет напряженно-деформированного состояния плиты и пологой оболочки. В точках нижней поверхности плиты (оболочки) определяются главные площадки и главные напряжения, строятся траектории наибольших растягивающих напряжений.
The stress-strain state of a slab and a shallow shell are calculated in the article. At the points of the lower surface of the slab (shell), the main areas and main stresses are determined, and the trajectories of the highest tensile stresses are constructed. The trajectories are compared with the schemes of crack development obtained on the basis of the experiment. A qualitative convergence between the calculated and experimental data is noted.
DECISION-MAKING METHODOLOGY UNDER UNCERTAINTY USING THE THEORY OF LATENT VARIABLES
Authors: Ананьев А.В. , Иванников К.С. , Моисеев С.И. 
Published: June 2022

В работе предлагается оригинальная методика оценивания альтернатив при принятии решений в условиях неопределенности, которая учитывает чувствительность альтернатив к изменению внешних условий. Приведены результаты вычислительных экспериментов, подтверждающие адекватность полученных оценок альтернатив.
This paper proposes an original method for evaluating alternatives when making decisions under conditions of uncertainty, which takes into account the sensitivity of alternatives to changes in external conditions. The results of computational experiments are presented, confirming the adequacy of the obtained estimates of alternatives. The developed scientific and methodological apparatus has considerable generality and can be extended to a wide range of decision-making problems.
INTEGRATED MECHANISM FOR PLANNING, CONTROL AND STIMULATION OF THE ACTIVITY OF TEACHERS IN HIGHER EDUCATION INSTITUTIONS
Authors: Койнов Р.С. , Кулаков С.М. , Гулевич Т.М. , Ляховец М.В. 
Published: June 2022

Описан новый механизм планирования, оценивания и стимулирования эффективности деятельности профессорско-преподаватель-ского состава, кафедр, институтов (факультетов) образовательного учреждения, учитывающий наличие государственного задания по видам деятельности и новых отраслевых аккредитационных показателей.
The article describes a new mechanism for planning, evaluating and stimulating the effectiveness of the activities of the teaching staff, departments, institutes (faculties) of an educational institution, taking into account the presence of a state assignment by type of activity and new industry accreditation indicators for educational programs. The formalization of the complex management mechanism, particular indicators are given, on the basis of which the final indicator of efficiency is calculated. The advantage of this mechanism, which ensures the implementation of the principle of coordinated planning, is shown. The theoretical basis of the developed proposals are: the theory of management of multilevel hierarchical organizational systems, system analysis.
DATA PRE-PROCESSING FOR COMPLEX SYSTEM BEHAVIOR ANALYSIS
Authors: Резова Н.Л. , Казаковцев Л.А. , Шкаберина Г.Ш. , Цепкова М.И. 
Published: June 2022

Рассматривается развитие методов предварительной обработки данных с целью классификации больших объемов данных на примере задачи анализа поведения экосистем. Результаты вычислительного эксперимента показали целесообразность их использования.
The article discusses the development of data preprocessing methods to classify large data amounts using the example of the problem of analyzing the behavior of ecosystems. The results of the computational experiment showed the feasibility of their use.
ADJACENT ELEMENTS OF INFORMATIVE SIGNALS AND THEIR APPLICATION IN THE ANALYSIS OF DYNAMIC PROCESSES
Authors: Цыганенко В.Н. , Белик А.Г. 
Published: June 2022

Предлагается и обсуждается применение прилегающих элементов как системный метод прикладного функционального моделирования информативных сигналов в задачах оценивания и анализа предельных состояний динамических процессов.
The use of adjacent elements is proposed and discussed as a systematic method of applied functional modeling of informative signals in the problems of estimating and analyzing the limit states of dynamic processes. Algorithms and methods of their application for the construction of linear and harmonic adjoinment models for the study of trends and periodicity of time series of data have been developed. Possibilities of using the technique in applied problems of analytical estimation and forecasting of dynamically changing processes are studied. The results of the studies showed the expediency of using the method in various applied problems of studying behavior in control and management systems for various purposes.
SOFTWARE AND ALGORITHMIC SUPPORT FOR MISSING DATA IMPUTATION
Authors: Глебова Е.А. , Пимонов А.Г. 
Published: June 2022

В статье представлено разработанное программное обеспечение импутирования пропущенных данных. В составе ядра созданной информационной системы реализованы различные алгоритмы и методы восстановления пропущенных наблюдений.
The article presents the developed software for imputation of missing data. As part of the core of the created information system, various algorithms and methods of missing observations recovery are implemented, the most promising of which is the evolutionary, which allows the complex use of neural network technology and a genetic algorithm.
INTELLIGENT ANALYSIS OF THE INFORMATION SECURITY EVENT FLOW NETWORK IDS
Authors: Горохов Д.Е. , Уваров Д.С. 
Published: June 2022

В статье рассматривается модель поиска аномалий в многомерном временном наборе признаков потока СИБ на основе метода роста ошибки предсказания в момент появления аномалии, основанная на рекуррентных нейронных сетях с долгой краткосрочной памятью LSTM. Описана математическая модель и приведены результаты ее применения.
The article considers a model for searching for anomalies in a multidimensional time set of SIB stream features based on the method of prediction error growth at the moment of anomaly occurrence, based on recurrent neural networks with long short-term memory LSTM. The mathematical model is described and the results of its application are presented.
INFORMATION SYSTEM FOR COMBINED DATA ANALYSIS OF VIDEONYSTAGMOGRAPHY AND ELECTROENCEPHALOGRAPHY
Authors: Непрокин А.В. 
Published: June 2022

Разработана информационная система для комбинированного сбора и анализа данных движений глаз и биоэлектрической активности головного мозга, позволяющая существенно повысить качество процесса диагностики неврологических расстройств.
An information system for the combined collection and analysis of eye movement and bioelectrical activity of the brain data has been developed, which significantly improves the quality of the process of diagnosing of neurological disorders.
MODERN INTELLIGENT FARM MANAGEMENT TECHNOLOGIES: CHALLENGES AND WAYS OF DEVELOPMENT
Authors: Авксентьева Е.Ю. , Кулешов С.В. , Зайцева А.А. , Суровцев В.Н. 
Published: June 2022

Представлено краткое резюме исследований, проведенных на взрослом крупном рогатом скоте, определяем существующее состояние, проблемы и возможные пути дальнейшего развития технологий мониторинга здоровья молочного скота и управления стадом.
This article provides a brief summary of research carried out on adult cattle, identifying the current status, challenges and possible ways forward for dairy cattle health monitoring and herd management technologies in real time.