bluuebunny/crossref_metadata_2025_split huggingface dataset:
AVALIAÇÕES REMOTAS EMERGENCIAIS EM UM CURSO DE LICENCIATURA EM MATEMÁTICA A DISTÂNCIA
Authors: Jocemar de Quadros Chagas  , Elisangela dos Santos Meza  , Ana Lúcia Pereira  
Published: April 2022

Este artigo apresenta o processo de adaptação das avaliações em um Curso de Licenciatura em Matemática ofertado na modalidade a distância de uma universidade pública no estado do Paraná, durante o período de pandemia da Covid-19. Como contextualização, apresenta-se brevemente a universidade e o Curso de Licenciatura em Matemática, assim como o histórico da oferta a distância do referido curso no âmbito da Universidade Aberta do Brasil (UAB). O processo avaliativo constante no Projeto Pedagógico do Curso é, também, apresentado, assim como algumas pertinentes reflexões acerca da avaliação em Matemática. Na sequência, destaca-se a adaptação das avaliações finais (tipicamente presenciais) ao formato remoto, motivada pelas restrições de mobilidade e aglomeração impostas pelo poder público como tentativas de contenção da pandemia do novo coronavírus, sempre ressaltando que Ensino Remoto Emergencial (ERE) não deve ser confundido com Educação a Distância (EaD). As estratégias emergenciais apontam que a inserção no AVA do registro das resoluções, realizadas durante as avaliações, motiva a desenvolver um olhar mais atento à forma como cada licenciando organiza o pensamento e raciocínio matemático. Além disso, a manutenção da exigência de produção escrita pelos estudantes nas atividades avaliativas serviu como um processo de “experimentação” e “reﬂexão” para professores e coordenadores do curso.
Palavras-chave: Licenciatura em Matemática. Educação a Distância. Práticas de avaliação. Avaliações finais. Avaliações remotas emergenciais.
Atelier experiences in interior architecture education: Zero waste approaches
Authors: Doğan Rabia Köse 
Published: April 2022

Workshops, seminars, ateliers, and charrettes, which are vocational courses and extracurricular activities taken outside of the studio courses, support studio education to a great extent. The "learning by doing" model gains significance in 21st-century interior architecture education. In this context, the application model of two workshops/ateliers held at different times within the scope of the study will be reviewed. The first of these consists of the Zero Waste Approach in Design Education Training Workshop-1, which was held face-to-face and organized by the Hacettepe University Faculty of Fine Arts, Department of Interior Architecture and Environmental Design in 2019, and the second, the Zero Waste Approach in Design Education Training Workshop-2, held online in 2021. From the study, participation in workshops and ateliers in interior architecture education boosts students' awareness, supports group work, increases synergy and motivation, and strengthens their design skills. The cooperation of institutions, on the other hand, expands the interaction and provides important contributions to interior architecture education.

Keywords: Atelier; Interior Architecture; Learning by Doing; Workshop; Zero Waste.
ystematic review on the clinical management of chronic pain and comorbid opioid use disorder
Authors: Jiménez-Fernández Beltrán , Calomarde-Gómez Cristina , López-Lazcano Ana , Lligoña Anna , Gual Antoni , López-Pelayo Hugo 
Published: April 2022

The crisis caused by prescribed opioids and their related side effects are a public health problem worldwide. Most of these are prescribed for coping with chronic pain. The coexistence of opioid use disorder (OUD) in patients with chronic pain represents a complex challenge due to the need for managing both pain and OUD. The aim of this systematic review is to evaluate the efficacy of feasible treatments for this population with OUD and comorbid chronic pain for both conditions. A systematic database search has been performed using Cochrane Library, MEDLINE, PsycINFO and ClinicalTrials.gov in compliance with PRISMA guidelines. Eligible articles addressed the outcomes in chronic pain patients with comorbid opioid use disorder after treatment interventions were applied. Of 593 identified articles, nine were eligible for qualitative review (n = 7 pharmacological interventions; n = 2 psychological interventions). Methadone, buprenorphine, cognitive-behavioral and mindfulness showed promising results, but data were inconclusive (<2 RCT with low risk of bias). It is unclear whether the opioid agonist treatment should be maintained or tapered and which drug should be prescribed for the opioid substitution therapy (methadone or buprenorphine/naloxone). Mindfulness and cognitive behavioral therapy have a discrete effect on improving negative affect but not pain. The therapeutic approach might be individualized under a shared decision-making basis.
Pengetahuan, Persepsi dan Sikap Perawat RSUD Arjawinangun tentang Asuhan Keperawatan Spiritual
Authors: Sutrisno Niko , Swasti Keksi Girindra , Mulyono Wastu Adi 
Published: April 2022

Background. Nursing considers humans as complex creatures which different one from another. They consist of biological, social, cultural, psychological and spiritual dimensions. However, the provision of spiritual care is not optimally delivered.Objective. This study was to describe nurses' knowledge, perceptions, and attitudes about spiritual careMethod. An observational study with cross sectional approach was conducted. Totally, 248 nurses worked in RSUD Arjawinangun Cirebon were invited to contribute in the study. The sample was collected by total sampling technique. Self-respon questioners were utilized, included knowledge, SSCRS and attitude scales. Univariate analyses were applied to describe the data.Results. Mosts of respondents indicated 10 years work experience. The education background varied from Diploma to Post-graduate, but the majority was Diploma 3 yrs. Female nurses dominated the sample with age ranged between 25 and 56 years old, but ages 26-35 dominatee the sample. Median scores of knowledge, perceptions and attitudes after being converted into 0-100 scale, all around 64.Conclusion. Scores of knowledge, perceptions and attitudes of Arjawinangun Hospital nurses about spiritual care were in mediocre levels.
Hubungan Peran Orang Tuadan Teman Sebaya dengan Perilaku Pencegahan Penyakit Menular Seksual (PMS) pada Remaja di SMK
Authors: Dini Ihtiara Ria , Ramadani Meida Laely 
Published: April 2022

Background:Teenagers experience physical, cognitive, socio emotional development. Curiosity and sexual fantasy cause teens to want to practice what adults do. Peers and the role of parents also play a very strong role in the attitude and prevention of sexually transmitted diseases (STDs). The role of parents is also important in the personal formation of adolescents. Parents have the role of helping teen increase self-confidence and teach teenagers to make decisions so as not to be influenced by their friends.Objective : To find out the relationship between the role of parents and peers with the prevention of sexually transmitted diseases (STDs) in adolescents at SMK Maarif Nu 1 Ajibarang.Method: This research is a quantitative descriptive study using cross sectional method. The sample of this study is the eleventh grade students namely 94 respondents taken by proportional random sampling. Questionnaire sheet is used to measure the instruments.Result: A total of 55 respondents (58.5%) and there are 73.4% respondents who are 17 years old. 64.9% Respondents received good influence from peers and 84.0% respondents with the good parents role. There are 53.2% adolescents with bad sexually transmitted disease prevention behaviors. The results of the analysis of peer variables and sexually transmitted disease prevention behaviors showed a significant relationship, with a p value = 0.002, and the role of parents with the prevention of sexually transmitted diseases also showed a significant relationship, with a p value = 0.005.Conclusion: There is a relationship between the role of parents and peers with the prevention of sexually transmitted diseases in SMK.
Effect of Massage Therapy on Chest Pain, Anxiety, and Stress Among Patients With Acute Coronary Syndrome: a review
Authors: Candra  , Isworo Atyanti , Setyo Upoyo Arif 
Published: April 2022

Background. Patients with acute coronary syndrome have many compalints such as: chest pain, anxiety, and stress. The management of these symotoms can be pharmacological and non-pharmacological therapy. One of non-pharmachological therapy that can be applied in acute coronary syndrome pastient is massage therapy. Massage therapy is an intervention that is easy to use, safe and inexpensive.
Methods. This study was conducted to reviews articles regarding massage therapy on chest pain, anxiety, and stress in patients with acute coronary syndrome. The literature search was carried out through the Google scholar, ScienceDirect, Pubmed and Proquest databases which the inclusion criteria were article in English from 2017 to 2012, an experiment research design. The search used keywords, namely “reflexotherapy” OR “hand and foot massage” AND “chest pain” OR “stress OR “anxiety” OR “acute coronary syndrome.
Results. There are 6 articles met criteria for analysis, 4 articles have good quality scores, and 2 articles in medium value. The articles shows the effectiveness of massage therapy on chest pain, anxiety and stress in patients with acute coronary syndrome.
Conclusion. Massage therapy effectiveness to reduce chest pain, anxiety, and stress in patients with acute coronary syndrome.
Maximizing the Proppant Carrying and Viscoelastic Properties of the Bakken Hypersaline-Produced Water with High-Viscosity Friction Reducers for Sustainable Applications
Authors: Tomomewo Olusegun Stanley , Mann Michael , Anyim Lawrence , Ellafi Abdulaziz , Tang Clement , Ba Geri Mohammed , Ibikunle Omolara 
Published: April 2022

Summary
The development and production of unconventional reservoirs, such as the Bakken Formation, have become a resolved mystery for operators in North America since the arrival and advancement of horizontal drilling and hydraulic fracturing technologies. As a result, unconventional reservoir assets became the central focus of the oil and gas industry at the state, national, and global levels. The produced water from these activities in the Bakken Formation have high salt contents (110,000–350,000 ppm) total dissolve solids (TDS) and can pose significant challenges to the environment if not treated. Deep injection into disposal wells is the routine method used to get rid of the Bakken produced water. However, there have been some concerns that unrestrained injections, in addition to polluting the groundwater, could potentially lead to seismic activities either at the time of injection or in the near future. To diminish the environmental impacts that may be associated with induced seismicity, including the reduction of the costs of water acquisition, the produced water can be treated and reused in the hydraulic fracturing processes. Also, the treated water could be used for irrigation purposes, for power generation, and coal mining operations. The issues of waste water and residual oil high in TDS are challenges yet to be effectively addressed despite preceding research and studies on advancing produced water technologies. The goal of this study is to explore all applicable ways by which the produced water from the Bakken Formation can serve as a replacement base fluid for use with polymers like the high-viscosity friction reducers (HVFRs) to create hydraulic fracturing fluids that can be stable with reservoir conditions and also be able to minimize environmental impacts and cost of operations. Experimental investigations using the high-salinity produced water from the Bakken Formation with HVFRs were carried out. The studies included a base case that served as a bench mark for comparing the effectiveness of the other scenarios. The results indicate that the Bakken hyper-saline produced water can withstand effect of heavy metals, salinity, hardness and remain stable through different shear rates (66–330 s−1) when treated with higher dosages [4–8 gal/1,000 gal (gpt)] of HVFRs. Filtration and dilution were the only methods used on the Bakken Formation produced wate for this research
Liquid Loading in Natural Gas Vertical Wells: A Review and Experimental Study
Authors: Alsanea Maziad , Mateus-Rubiano Camilo , Karami Hamidreza 
Published: April 2022

Summary
Liquid loading in natural gas wells is one of the main causes of decline and eventual cease of production. Identifying the onset of liquid loading and its impacts on production is vital in production optimization of gas wells. In this study, a new state-of-the-art experimental facility is used to analyze two-phase flow parameters, such as liquid and gas velocities, pressure drop, liquid holdup, and flow pattern, and study the onset of liquid loading. Experiments are conducted using air and water in a 0.0508-m (2-in.) internal diameter (ID) vertical flow loop. The facility is designed to eliminate any source of disruption to the flow in a temperature-controlled indoor environment to avoid changes in fluid properties. A wide range of data are collected related to the onset of liquid loading and in the churn region. The acquired data are compared with other studies to ensure the accuracy and repeatability of the tests.
A quantitative method is developed to predict the onset of liquid loading, namely, the positive frictional pressure gradient (negative pressure drop). A comparison is made between the visual observations for flow pattern transition, positive frictional pressure gradient, and minimum pressure drop. Overall, the results show that the positive frictional pressure gradient approach can provide a better estimation of the onset of liquid loading than the minimum pressure drop approach. Additionally, Tulsa University Fluid Flow Project (TUFFP) unified model (v2016) and OLGA (v2016.2.1) are used to evaluate the average pressure drop, liquid holdup, and flow pattern. Furthermore, the liquid film reversal model, liquid droplet models, and inflection point approach are included in the comparison of the onset of liquid loading with experimental data. The OLGA model predicts the results more precisely than other models. The comparison with the experimental data indicates that inaccurate flow pattern predictions could significantly increase the relative errors in pressure drop and liquid holdup. In addition, the evaluation of OLGA results suggests the need to develop a model for churn flow, as the relative error increases sharply in the churn flow with the model predicting the transition to slug flow.
Mitigating fungi-related nitrous oxide emissions by application of industrial waste in an acidic soil
Authors: Yin Junhui , Cui Wenjing , Xu Yumeng , Ma Yan , Chen Huaihai , Guo Jingheng , Liu Rui , Chen Qing 
Published: April 2022

Abstract
Alkaline industrial wastes to arable soils have the potential to ameliorate soil acidification and improve crop yield. However, the impact of such amendments with N fertilizers on soil nitrous oxide (N2O) emissions and the mechanisms involved remain elusive. Two incubation experiments were conducted to explore the effects of an alkaline amendment (Phosphorus tailing (PT), a waste product of phosphorus mineral flotation process) on N2O emissions and microbial mechanisms from an acidic soil. Four treatments in the first experiment were set as: i) control (CK), ii) urea (U), iii) PT amendment (S) and iv) PT amendment plus urea (S+U). The second experiment was conducted to access the relative contributions of fungi and bacteria to N2O emissions. Results from the first experiment showed that PT amendment significantly increased soil pH from 4.8 to above 6.0, and reduced N2O emissions by an average of 65.7%. Higher N2 emissions and faster O2 consumption were observed after applying the amendment than untreated soils at the end of incubation. PT amendment significantly increased extracellular enzyme activities of leucine aminopeptidase and N-Acetyl-β-glucosaminidase, while significantly decreased activities of β-1, 4-glucosidase and β-cellobiosidase. In comparison to soil with urea, urea with PT amendment raised soil bacteria-related N2O from 9.18% to 18.8% while decreasing fungi-related N2O from 50.5% to 43.2%. These findings suggest that the N2O emissions from acidic soils can be considerably mitigated by application of alkaline industrial wastes. The contribution of fungi should be considered when designing and applying N2O mitigation strategies in acidic soils.
FN1 Is a Prognostic Biomarker and Correlated With Immune Infiltrates in Thyroid Carcinoma and Breast Invasive Carcinoma
Authors: wu yaqin , Zhang Chaojie , Zou Lianhong , Chen Yiru , Xiao Xiangyuqin , Jiang Yu , Feng Yang 
Published: April 2022

Abstract
Background: Fibronectin 1 (FN1), an important extracellular matrix glycoprotein encoded by FN1 gene. Thyroid carcinoma (TC) and breast carcinoma (BC) have always been a threat to women's physical and mental health. However, the relationship between FN1 expression, tumor immunity, and prognosis in TC, BC remains unclear. Methods: FN1 expression and its influence on tumor prognosis were analyzed by the ONCOMINE, Tumor Immune Estimation Resource (TIMER) and Kaplan-Meier plotter. The relationship between FN1 expression and tumor immunity was analyzed by TIMER and Gene Expression Profiling Interactive Analysis (GEPIA). Results: FN1 expression was significantly higher in several human cancers, including TC, BC than in corresponding normal tissues. FN1 expression in TC, BC tissues correlated with prognosis. High FN1 expression associated with poorer relapse-free survival (RFS) in TC patients and poorer post progression survival (PPS), RFS, distant metastasis-free survival (DMFS) in BC patients, particularly at higher T stage and N stage. FN1 showed strong correlation with B cells, CD8+T cells, CD4+T cells, macrophages, neutrophils, and dendritic cells. Conclusion: These findings demonstrate that FN1 is a potential prognostic biomarker that determines cancer progression and correlated with tumor immune cells infiltration in TC and BC.
Modified Technique for Corneal Laceration Repair Using Amniotic Membrane.
Authors: Elkadim Mohamed , Elgohary Asmaa M , Alhelaly Mai Brakat , Sharaf Amr F. 
Published: April 2022

Abstract

Background: To describe technique and evaluate outcomes of using amniotic membrane onlay strip for repair of corneal lacerations.Methods: Retrospective case series included eight eyes with traumatic corneal lacerations. A strip of amniotic membrane was applied to the corneal surface to cover the wound. Wound was then sutured with nylon 10/0 sutures involving the membrane. Sutures were well-spaced and suturing was avoided in the visual axis. Average keratometric reading (average K), keratometric astigmatism (KA), manifest refractive astigmatism (RA) in diopters (D) and spectacle or soft contact lens best corrected visual acuity (BCVA) were assessed 2 months after suture removal. Results: Transient postoperative hypotony was encountered in five cases (62.5%). Average K was 44.61 ± 2.81 D (mean± SD). KA was 2.20±0.71 D (mean± SD). RA was 1.78 ± 0.73 D (mean± SD) and ranged from 1 to 3 D. Log MAR BCVA was 0.39±0.18 (mean± SD) ranged from 0.22 to 0.70.Conclusions: The application of amniotic membrane onlay strip during repair of corneal lacerations was associated with good visual outcome possibly due to reduction of wound and suture related corneal astigmatism.
Spectral Clustering-based System for Spike-Sorting
Authors: Ranjbar Leila , Parsaei Hossein , Movahedi Mohammad Mehdi , Javidi Sam Sharifzadeh 
Published: April 2022

Abstract
Acquisition and analyzing the nerve action potentials is a fundamental part of studying the nervous system. A major step in such analysis is spike sorting. Here, we proposed a spike sorting method using the spectral clustering (SC) technique. Various features including raw samples, first and second derivatives (FD, SD), and principal component analysis (PCA), were used to represent spikes. PCA was also used to estimate the number of clusters. A new criterion separability index (SI) was proposed to quantitively measure the difficulty of extracting spike trains from a given signal. The results support our hypothesis about the good performance of spectral clustering on neural data, especially when using raw data samples as features that reduce the computational cost and assist with fast spike sorting. The results, also showed that the proposed index could disclose spike sorting difficulty, so it could be a useful complement to the spike sorting procedure as a classifier to decide which signal may need extra human correction. Such grouping might help with reducing both cost and processing time in analyzing large datasets.
25-hydroxyvitamin D is associated with islet function homeostasis in type 2 diabetes patients with abdominal obesity
Authors: Li Qing , Zhang Wen , Han Bing , Wang Yuying , Wan Heng , Wang Ningjian , Lu Yingli 
Published: April 2022

Abstract
Aim: Islet α-cells input is essential for insulin secretion from β-cells. The role 25-hydroxyvitamin D (25(OH)D) on islet α-cells function is unclear. We aimed to investigate the association between 25(OH)D and islet function homeostasis in type 2 diabetes (T2D) patients. Methods: Total 4670 T2D patients were enrolled from seven communities in Shanghai, China. Anthropometric indices, biochemical parameters, serum 25(OH)D, and islet function including C-peptide (C-p) and glucagon were measured.Results: With increase in 25(OH)D level, FPG, HbA1c, glucagon and C-p were significantly decreased in trend in T2D patients. The population were divided into abdominal obesity and non-abdominal obesity group. 25(OH)D level was associated with HbA1c, glucagon and HOMA-β in non-abdominal obesity group after adjustment. As for abdominal obesity group, there was the significant association between 25(OH)D and HbA1c, glucagon, HOMA-IR, baseline insulin and C-p. The OLS regression and quantile regression further showed that 25(OH)D was associated with glucagon and fasting C-p levels in T2D patients with abdominal obesity. In non-abdominal obesity group, the OLS regression showed that the regression coefficients were not significant in 50th percentile for HOMA-β. The moderate analyses revealed significantly interaction effect of 25(OH)D and glucagon on C-p (P=0.0124), as well as the effect of 25(OH)D and duration of diabetes on glucagon/C-p in abdominal obesity group. According to the range of the duration of diabetes, the conditional indirect effect of 25(OH)D on glucagon/C-p was significantly at 1 SD below the mean (P=0.0002) and the mean of the duration of diabetes (P=0.0007).Conclusion: 25(OH)D was negatively associated with glucagon and C-p in T2D patients with abdominal obesity. Duration of diabetes influence the effect of 25(OH)D on the ratio of glucagon/C-p, on behalf of islet function homeostasis, in T2D patients with abdominal obesity.
Nickel concentration in gills is correlated with shell height in European freshwater duck mussels (Anodonta anatina)
Authors: BERKEL CAGLAR , CACAN Ercan 
Published: April 2022

Abstract
The potential correlations between the concentrations of a number of elements in gills (mg/kg) and shell height (mm) were investigated in European freshwater duck mussels, Anodonta anatina. Our results showed that nickel (Ni) concentration in gills is moderately correlated with shell height in these animals, with correlation coefficient (r) of 0.698. Other elements (As, Cr, Zn, Fe, Pb, Cd, Ca, Mn, Na, K, Co, Hg and Cu) show low (0.3<r<0.5) or almost no correlation (r<0.3) with shell height, with the exception that Arsenic (As) in gills is moderately correlated with shell height (r = 0.532) in duck mussels.