bluuebunny/crossref_metadata_2025_split huggingface dataset:
Physiological and Biochemical Effects of Heavy Metals on Wheat Seedlings in Northern Xuzhou
Authors: Luan Huijun , Xiao Xin , CONDE Sékou Mohamed , Wang Li , Xing Mingjie , Liang Yan , Lu Yin 
Published: May 2022

Abstract
Storage and transportation of coal，and operation of the coal fired power plant produce a large amount of waste water, gas and solid waste, which may lead to enhanced levels of heavy metals in overlapped areas of farmland and coal resources (OAFCR) environment. A field experiment was conducted to explore heavy metal (Cr, Cd, Cu, Zn, Pb and As) stress in environment on wheat seedlings (AK-58) growing in OAFCR region (north of Xuzhou) and the area in the southern suburb of Xuzhou. The results show that (1) Compared with the southern suburb of Xuzhou, the biomass (fresh and dry weight) of wheat was significantly lower in OAFCR. (2) The activities of photosynthetic enzymes and POD were significantly lower in OAFCR, but the activities of SOD and CAT were higher, compared with the area in the southern suburb of Xuzhou. (3)The content of Cr,Cd,Pb,Zn in shoot and Cr,Cd,Pb,Zn,Cu in root of wheat growing in OAFCR were all significantly higher than in the southern suburb of Xuzhou; Translocation factors (TF) of elements（except Cd） were lower in OAFCR . The BCF values of heavy metals in wheat in OAFCR were also exceed that in the southern suburb of Xuzhou by approximately 199% (Cd), 110% (Pb), 61% (Cr), 37% (Zn), 27% (Cu) and 7% (As) respectively. (4)The subcellular analysis showed that the Pb, Cu, Cd, Zn and Cr absorbed by wheat were stored primarily in the cell walls and the soluble fractions. Both the contents of Cu , Cr in wheat cell walls and the contents of Pb, Cu and Zn in soluble components in OAFCR were all significantly higher than in the southern suburb of Xuzhou
Superlubricity under ultrahigh contact pressure enabled by self-assembled fluorinated azobenzene layers
Authors: Xue Dandan , Ma Liran , Wen Shizhu , Luo Jianbin 
Published: May 2022

Abstract
Extensive efforts have been made to pursue an ultralow-friction state, which is known as superlubricity, with promising applications in many fields, such as mechanical and biomedical engineering. The load capacity of superlubricity has been considered to be crucial for industrial applications. Here, we report superlubricity under ultrahigh contact pressure by building a novel self-assembled fluorinated azobenzene layer on an atomically smooth highly oriented pyrolytic graphite (HOPG) surface. Sliding friction coefficients could be as low as 0.0005 or even lower under a contact pressure of up to 4 GPa. This ultralow-friction is attributed to molecular fluorination, which significantly weakens the intermolecular force between the close-packed fluorine atoms arrayed between the HOPG surface and the silicon atomic force microscopy (AFM) probe. This work provides a new approach to solid superlubricity under relatively high contact pressure, which might has great potential application value in the future.
Elucidation of peripheral nerve myelination by bimodal waveform analysis in the pediatric population
Authors: Okuma Aiko , Nakamura Tomohiko , Katsuno Masahisa , Matsushita Tadashi 
Published: May 2022

Abstract
Purpose
As the myelin sheath of the peripheral nerves is immaturely developed in children, a bimodal waveform may be evoked when sensory nerve conduction studies are performed in them. However, there has been no study regarding the relationship between age and the frequency of appearance of the bimodal waveform or the intervertex latency. Herein, we examined how the bimodal waveform changes with age.
Methods
A total of 218 sensory nerves (109 median and 109 ulnar nerves) in 86 children (0 to 15 years old) were analyzed. The frequency of the bimodal waveform and the distance-corrected intervertex latency were examined with antidromic sensory nerve conduction studies of the upper limbs on proximal stimulation.
Results
The frequency of bimodal waveforms and distance-corrected intervertex latency decreased with age. Analysis of the slope line of the scatter plot demonstrated that the bimodal waveform was present until the age of 15–16 years.
Conclusion
The bimodal waveform of sensory nerves faded with growth. Given that development-associated temporal dispersion is considered to be the cause of the differences in the bimodal waveform, our results indicate that the myelin sheath in peripheral nerves continues to develop until approximately 15–16 years.
Assessment of Resected Liver Fibrosis Stages by Preoperative/Intraoperative Needle Biopsy among Hepatocellular Carcinoma Patients
Authors: Kuramitsu Kaori , Fukushima Kenji , Yano Yoshihiko , Itoh Tomoo , Kido Masahiro , Komatsu Shohei , Tsugawa Daisuke , Ajiki Tetsuo , Toyama Hirochika , Fukumoto Takumi 
Published: May 2022

Abstract
Purpose: Posthepatectomy liver failure (PHLF) is a major complication of hepatectomy. Although the extent of liver resection and fibrosis stages were previously identified as predictors of the development of PHLF, fibrosis stages were diagnosed using samples from resected livers. We evaluated the association between preoperative/intraoperative liver biopsies and final fibrosis stages.Methods: We included 272 patients who underwent an initial hepatectomy at our facility between January 2014 and December 2018.Results: PHLF occurred in 70 patients (25.7%) and decreased their overall survival (p = 0.0001). Preoperative/intraoperative liver biopsies showed a significant correlation with final fibrosis stages (p < 0.0001). The underestimation rates of preoperative and intraoperative F0/F1/F2 were 16.9% and 28.2%, respectively. Among the preoperative factors, 99mTc-GSA scintigraphy LHL < 0.91 was significantly associated with the resected liver fibrosis stages (hazard ratio [HR], 2.38; 95% confidence interval [CI]: 1.37–4.21; p = 0.0022). The underestimation rates of preoperative F0/F1/F2 with 99mTc-GSA scintigraphy LHL > 0.91 and <0.91 were 14.3% and 23.5%, respectively. None of the patients had underestimated final fibrosis stages based on intraoperative biopsies. The intraoperative fibrosis stages perfectly matched with final fibrosis stages in 86.4% of the cases, but the final fibrosis stages were overestimated in 13.6%.Conclusions: The fibrosis stages of the resected livers were associated with preoperative and intraoperative liver biopsies. Successful hepatectomies could be performed in accordance with findings from preoperative liver biopsies, 99mTc-GSA scintigraphy, and intraoperative liver biopsies without the incidence of PHLF.
Genome-based reclassification of Anoxybacillus karvacharensis Panosyan et al. as a later heterotypic synonym of Anoxybacillus kestanbolensis Dulger et al. 2004
Authors: BEKTAS Kadriye INAN , GULER Halil İbrahim , CANAKCI Sabriye , BELDUZ Ali Osman 
Published: May 2022

Abstract
In the present study, we attempted to clarify the relationship between Anoxybacillus karvacharensis K1T and Anoxybacillus kestanbolensis NCIMB13971T by using whole-genome phylogenetic analysis. The genome sequence of A.kestanbolensis NCIMB13971T was not available in any database, so it was sequenced in this study. The 16S rRNA gene sequence obtained from the genome of A.kestanbolensis NCIMB13971T had 99.93% similarity with A.karvacharensis K1T. Also, A.karvacharensis K1T and A.kestanbolensis NCIMB 13971T formed a robust branch different from other type strains of Anoxybacillus in the phylogenetic trees based on whole-genome sequences and 16S rRNA gene sequences. The average nucleotide identity (ANI), average amino acid identity (AAI) and digital DNA–DNA hybridization (DDH) values between A.karvacharensis K1T and A.kestanbolensis NCIMB13971T were greater than the threshold values for species demarcation. The present results indicate that both strains were considered to belong to the same species and A. karvacharensis K1T is later heterotypic synonym of A.kestanbolensis NCIMB13971T.
Grounded Theory-Based Model of Digital Communication’s Influence on Handicraft Intangible Cultural Heritage
Authors: li jia , Kim KieSu 
Published: May 2022

Abstract
The digital environment has altered the means of social interaction and information transmission, creating new media and models of cultural communication. Despite extensive investigations of the effect of digital communication on handicraft intangible cultural heritage (ICH), research on the relationship between factors influencing digital communication of handicraft ICH is relatively scarce. In this study, therefore, we obtained data related to influencing factors of digital handicraft ICH communication through in-depth interviews and text analysis. Then, using grounded theory, five core factors were found to have significant effects on the digital communication of handicraft ICH: digital communication awareness, initiative of cultural communication, adaptability of digital technology, audience acceptance and cognition, and uncontrollable factors. Furthermore, by analyzing the relationships among the five independent variables, a theoretical model of “consciousness–behavior–attitude” was constructed. Finally, the action mechanism of the theoretical model was identified and tested, and the action modes of each influencing factor were found to be inconsistent. Antecedent factors were directly proportional to consciousness–behavior, situational factors were inversely proportional to consciousness–behavior, and regulatory factors were inversely proportional to behavior–attitude. In addition, situational factors and regulatory factors had a positive impact on antecedent factors.
Effect of mesoscale eddies on the transport of low-salinity water from the Bay of Bengal into the Arabian Sea during winter
Authors: Zhu Jiechao , Zhang Yuhong , Cheng Xuhua , Wang Xiangpeng , Sun Qiwei , Du Yan 
Published: May 2022

Abstract
Significant contrast in sea surface salinity (SSS) emerges between the Arabian Sea (AS) and Bay of Bengal (BoB) caused by distinct air-sea freshwater flux and runoff inputs. The monsoon-induced inter-basin water exchange plays an important role in regional salinity balance and atmosphere-ocean feedback in the North Indian Ocean. The satellite SSS dataset reveals that significant intraseasonal variabilities of SSS occur in the south of India with stronger amplitude in winter than in summer. A case study in the late fall and earlier winter of 2016 shows that the Northeast Monsoon Current (NMC) and an eddy pair developed in the south of India plays a vital role in the intraseasonal variabilities of SSS there. In November, the East India Coasta Current (EICC) transports the low-salinity water southward to the east side of Sri Lanka. Meanwhile, a cyclonic eddy develops and propagates westward in the south of the NMC. Both NMC and the cyclonic eddy advects the low-salinity water westward to the south of India. Then, an anticyclonic eddy generates in the north of the NMC, forming an eddy pair with the cyclonic eddy. This eddy pair develops and propagates westward in the south of India for more than one and a half months, transporting low-salinity water westward. The perturbation of eddies and SSS gradient leads to the significant intraseasonal variability of SSS there.
Machine Learning-based Calibration of the GOCE Satellite Platform Magnetometers
Authors: Styp-Rekowski Kevin , Michaelis Ingo , Stolle Claudia , Baerenzung Julien , Korte Monika , Kao Odej 
Published: May 2022

Abstract
Additional datasets from space-based observations of the Earth's magnetic field are of high value to space physics and geomagnetism. The use of platform magnetometers from non-dedicated satellites has recently successfully provided additional spatial and temporal coverage of the magnetic field. The Gravity and steady-state Ocean Circulation Explorer (GOCE) mission was launched in March 2009 and ended in November 2013 with the purpose of measuring the Earth's gravity field. It also carried three platform magnetometers onboard. Careful calibration of the platform magnetometers can remove artificial disturbances caused by other satellite payload systems, improving the quality of the measurements. In this work, a Machine Learning-based approach is presented that uses neural networks to achieve a calibration that can incorporate a variety of collected information about the satellite system. The evaluation has shown that the approach is able to significantly reduce the calibration residual with a mean absolute residual of about 6.47nT for low-and mid-latitudes. In addition, the calibrated platform magnetometer data can be used for reconstructing the lithospheric field, due to the low altitude of the mission, and also observing other magnetic phenomena such as geomagnetic storms. Furthermore, the inclusion of the calibrated platform magnetometer data also allows improvement of geomagnetic field models. The calibrated dataset is published alongside this work.
Detection of Sebaceous Gland Hyperplasia with Dermoscopy and Reflectance Confocal Microscopy
Authors: Rao Lang , Lin Er-Yi , Wang Weng-Ju , Huang Xiao-wen 
Published: May 2022

Abstract
Sebaceous gland hyperplasia (SGH) is a benign cutaneous proliferation of the sebaceous glands that occurs in approximately 1% of the healthy population, mainly males. Our aim was to describe dermoscopy and reflectance confocal microscopy features of sebaceous gland hyperplasia. Thirty-one patients with sebaceous gland hyperplasia diagnosed according to the clinical and histopathological standards were examined using dermoscopy and reflectance confocal microscopy (RCM) from March 2018 to January 2022. Dermoscopically, lesions revealed yellowish-red background and faintyellow background in 25 cases (80.65%) and 6 cases (19.35%) respectively. White-yellowish lobulated structures in the center of the lesion were presented in 31 cases (100%) and umbilications in 19 patients (61.29%). Crown vessels in the peripheral of the lesions were observed in 11 cases (35.48%) while irregular linear vessels on the surface of the lesions in 18 cases (58.06%). Under the reflectance confocal microscopy, all lesions presented a honeycombed pattern in the epidermis and typical morulae-shaped sebaceous lobules in dermis. Dilated follicular infundibulum was observed in 15cases (48.39%) and dilated vessels in 26 cases (83.87%). In conclusion, dermoscopy and RCM enable us to describe the imaging features of SGH. Combing the two useful tools together provides a non-invasive basis for the accuracy of clinical diagnosis.
Attention Vision Transformers for Human Fall Detection
Authors: Bakshi Satyake 
Published: May 2022

Abstract
In recent years, Attention transformers have proven to be instrumental in Natural Language Processing (NLP) based tasks like sentence classification, and language translation. However, their application has been recently extended to large-scale object recognition tasks. In this work, Vision Transformer with attention has been investigated for the detection of human falls and ADLs (Activities of Daily Living) from time series-based signals. The Vision Transformer model has been trained and validated using the accelerometer signals of waist-worn Inertial Measurement Unit (IMU) sensors obtained from the IMU Falls dataset. The model is also trained and validated on the popularly used SiSFall dataset. The model is also investigated by independently training on 3 different cases of patch size and attention heads. It is observed that a larger patch size has resulted in significant performance deterioration. Additionally, smaller patch size took longer to train and was computationally expensive. The model performed (best-case) with an Accuracy (%) of 99.9 ± 0.1 and a True Positive Rate (%) of 99.9 ± 0.1 on the SFU-IMU dataset and with an Accuracy (%) of 99.8 ± 0.25 and a True Positive Rate (%) of 99.87 ± 0.3 on the SISFALL dataset. Overall, the results show that Transformers are highly robust in the detection of human falls and non-falls/ADL subject to the appropriate patch size.
Unrelated umbilical cord blood can improve the prognosis of haploidentical hematopoietic stem cell transplantation
Authors: Yang Ying , Zhang Ming , Li Mengqi , Li Yingchun , Yang Wei , Liu Zhuogang , Wang Hongtao 
Published: May 2022

Abstract
Background: Haploidentical hematopoietic stem cell transplantation (haplo-HSCT) is widely used as a curative treatment strategy for most types of hematological diseases. However, strategies for enhancing the graft versus leukemia (GVL) effect without aggravating the graft versus host disease (GVHD) effect are still being pursued.Methods: A retrospective cohort study was performed to compare the outcomes between combined unrelated umbilical cord blood (UCB-haplo HSCT) and haplo HSCT. Results: The results showed that neither aGVHD nor cGVHD was increased in the UCB-haplo HSCT group, and the engraftment and infection rates were similar between the two groups. However, overall survival (OS) and progression-free survival (PFS) were significantly improved, while transplantation-related mortality (TRM) and relapse were significantly decreased in the UCB-haplo HSCT group by both univariate and multivariate analyses. Conclusion: Our results indicated that the addition of a UCB unit could improve the prognosis of haplo-HSCT and enhance the GVL effect without increasing the incidence of GVHD. Trial registration: The cohort study was retrospectively registered at https://www.chictr.org.cn as ChiCTR2100046681.
Attribution of runoff variation to climate and human-driven changes in the transition zone between the Qinling Mountains and the Loess Plateau under vegetation greening
Authors: Wu Yanrui , Zhang Hongbo , Lan Tian , Wei Xingchen , Shao Shuting , Zhang Jingru , Ding Hao 
Published: May 2022

AbstractThe need for water safety management has increased in the transition zone between the Qinling Mountains and the Loess Plateau, China due to streamflow decline over the past 30 years. Vegetation greening, largely due to the result of the ‘Grain for Green’ program implemented in the Loess Plateau, is affecting regional streamflow together with climate change and direct human impacts. There is thus an urgent need to evaluate the relative importance of causes of streamflow variation in this region. A Hydrological Model of L′École de Technologie Supérieure (HMETS)-based segment identification analysis framework was presented to quantify the impacts of climate and human-driven changes on runoff under regional vegetation greening. Results showed that climate change and human interference were alternately dominant in the hydrological cycle from 1976 to 2015. Climate change played a major role in affecting runoff variation before 2000, and then human interference dominated. It is worth noting that temperature increases resulted in runoff reduction and induced more changes in streamflow when precipitation was high. Vegetation greening contributed highly to streamflow attenuation, and its impact on runoff variation was more significant after 2007. Generally, understanding the effects of temperature increases and vegetation greening on streamflow is important for the development of appropriate adaptation strategies for the planning and management of regional water resources.
Novel water treatment system in a low-resource community
Authors: Nogueira R. C. , Nigro M. , Veuthey J. , Thior M. D. F , Amour C. O. D. , Voillat J. 
Published: May 2022

Abstract
This paper evaluates the performance of a low-cost technology in rural Benin (West Africa) that locally produces chlorine (sodium hypochlorite) and then injects it into the community water tanks. Thirty-one water tanks were selected in cooperation with local authorities to receive electro-chlorinator devices (WATA™). Water samples were tested at two points: before chlorination and at the most distant terminal after chlorination. Residual chlorine control tests and microbiology control tests were performed. Water samples that tested positive for the presence of microorganisms were analyzed at a laboratory when possible. The water provided to the community was not always chlorinated, and over half of the tanks lacked access to chlorine powder. Among the sites using the technology, 30% (9/31) of them had structural problems that prevented the existing system from performing adequately. Furthermore, 60% of the water samples collected before chlorination were positive for microbiological contamination. All samples collected from systems where proper chlorination was taking place tested negative for microbiological contamination. However, the water from six tanks presenting structural problems continued to be distributed to the population despite contamination. The average residual chlorine level analyzed at the most distant terminal fountain was 0.29±0.2 mg/L, which is within the country's reference level 0.1–0.8 mg/L. The installation of water-chlorinator devices (WATA™) produces water without microbiological contamination and with chlorine levels within the WHO's recommended values. However, the success of the technology depends on the pre-existing structure of the water tank.
Effects of Pharmacogenomic Testing in Clinical Pain Management: Retrospective Study
Authors: Tagwerker Christian , Carias-Marines Mary Jane , Smith David J 
Published: May 2022

Background
The availability of pharmacogenomic (PGx) methods to determine the right drug and dosage for individualized patient treatment has increased over the past decade. Adoption of the resulting PGx reports in a clinical setting and monitoring of clinical outcomes is a challenging and long-term commitment.

Objective
This study summarizes an extended PGx deep sequencing panel intended for medication dosing and prescription guidance newly adopted in a pain management clinic. The primary outcome of this retrospective study reports the number of cases and types of drugs covered, for which PGx data appears to have assisted in optimal drug prescription and dosing.

Methods
A PGx panel is described, encompassing 23 genes and 141 single-nucleotide polymorphisms or indels, combined with PGx dosing guidance and drug-gene interaction (DGI) and drug-drug interaction (DDI) reporting to prevent adverse drug reactions (ADRs). During a 2-year period, patients (N=171) were monitored in a pain management clinic. Urine toxicology, PGx reports, and progress notes were studied retrospectively for changes in prescription regimens before and after the PGx report was made available to the provider. An additional algorithm provided DGIs and DDIs to prevent ADRs.

Results
Among patient PGx reports with medication lists provided (n=146), 57.5% (n=84) showed one or more moderate and 5.5% (n=8) at least one serious PGx interaction. A total of 96 (65.8%) patients showed at least one moderate and 15.1% (n=22) one or more serious DGIs or DDIs. A significant number of active changes in prescriptions based on the 102 PGx/DGI/DDI report results provided was observed for 85 (83.3%) patients for which a specific drug was either discontinued or switched within the defined drug classes of the report, or a new drug was added.

Conclusions
Preventative action was observed for all serious interactions, and only moderate interactions were tolerated for the lack of other alternatives. This study demonstrates the application of an extended PGx panel combined with a customized informational report to prevent ADRs and improve patient care.