bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of Mental Disorders in Patients With Chronic Thromboembolic Pulmonary Hypertension
Authors: Dering Madelaine-Rachel , Lepsy Nicole , Fuge Jan , Meltendorf Tanja , Hoeper Marius M. , Heitland Ivo , Kamp Jan C. , Park Da-Hee , Richter Manuel J. , Gall Henning , Ghofrani Hossein A. , Ellermeier Dietmar , Kulla Hans-Dieter , Kahl Kai G. , Olsson Karen M. 
Published: March 2022

ObjectivePulmonary hypertension (PH) is a chronic and progressive pulmonary vascular disease resulting in symptoms such as shortness of breath and fatigue and leading to death from right heart failure if not adequately treated. Chronic thromboembolic pulmonary hypertension (CTEPH) is a subgroup of PH characterized by obstruction or occlusion of pulmonary arteries by post-embolic fibrotic material. To date, few studies examined symptoms of depression and anxiety in patients with CTEPH, showing depression levels as high as 37.5%. However, none of the former studies used structured expert interviews.MethodsMental disorders were diagnosed using the Structured Clinical Interview for DSM-5 (SCID). The prevalence of mental disorders in patients with CTEPH were compared to the prevalence in patients with pulmonary arterial hypertension (PAH) and the general German population. Quality of life (QoL) was measured with World Health Organization (WHO) Quality of Life questionnaire (short form). Factors associated with QoL were analyzed with linear regression and the diagnostic value of the Hospital Anxiety and Depression Scale (HADS) was evaluated using receiver operating characteristics (ROC) curve analysis.ResultsHundred and seven patients with CTEPH were included. Almost one-third of the patients (31.8%) had current psychological disorders. Panic disorder (8.4%), specific phobia (8.4%), and major depressive disorder (6.5%) were the most prevalent mental illnesses. The prevalence of panic disorders was higher in CTEPH compared to the German population while major depressive disorder was fewer in CTEPH compared to PAH. The presence of mental disorders had a major impact on QoL. Hospital Anxiety and Depression Scale discriminated depression and panic disorder reliably.ConclusionMental disorders are common in patients with CTEPH and associated with an impaired QoL. The HADS may be a useful screening tool for panic and depression disorders in patients with CTEPH. Further research on therapeutic strategies targeting mental disorders in patients with CTEPH is needed.
International Publication Trends in Low Back Pain Research: A Bibliometric and Visualization Analysis
Authors: Huang Fan , Zheng Beisi , Wu Cunshu , Zhao Siyi , Xu Yuanyue , Li Ziyuan , Huang Chuyu , Fan Zhiyong , Wu Shan 
Published: March 2022

BackgroundAlthough there is a growing research base on low back pain, the bibliometric literature related to it is deficient. The aim of this study was to conduct a bibliometric and visualization analysis of low back pain and to provide a broad view of the current trends in LBP research and a potential guide in this discipline.MethodsThe authors searched the Web of Science to extract publications regarding low back pain, and found a total of 12,249 publications during a period of 22 years, among which 12,242 were eligible. We classified and analyzed publications such as total citations, average citations per item, H-index, research types, countries/regions, institutions, and journals using standard bibliometric indicators. Bibliometric approaches (VOSviewer1.6.13 and CiteSpace 5.8.3) were also available for gathering information and explore the trends of research.ResultsConspicuously, over the past 22 years, an increasing number of scholars have specialized in the research of LBP, exerting the boom in articles. The largest number of document type was that of articles. Under modern conditions, regional distinction existed in the research of low back pain and developed countries preceded others. Research individuals and institutions were preoccupied by respective aspects. Visualization analysis provided objective information for potential collaborators and cooperative institutions. Furthermore, most burst keywords varied during different periods.ConclusionsThe map of research on LBP obtained by our analysis is expected to help researchers to efficiently and effectively explore LBP.
Cost-Effectiveness Analysis of Pembrolizumab in Patients With Advanced Esophageal Cancer Based on the KEYNOTE-181 Study
Authors: Zhan Mei , Xu Ting , Zheng Hanrui , He Zhiyao 
Published: March 2022

Background and PurposeThe KEYNOTE-181 study demonstrated that pembrolizumab for advanced or metastatic esophageal cancer in patients with programmed death ligand-1 (PD-L1) combined positive score (CPS) ≥ 10 had a survival advantage and better tolerability than chemotherapy. However, at the same time, pembrolizumab places an economic burden on patients. This study assessed the cost-effectiveness of pembrolizumab based on the KEYNOTE181 study.Materials and MethodsA three-state Markov model [progression-free survival (PFS), progressive disease (PD), and death] based on data from the KEYNOTE-181 study was used to estimate the incremental cost-effectiveness ratio (ICER) of pembrolizumab versus chemotherapy for advanced or metastatic esophageal cancer. The model evaluates the outcomes from the Chinese society's perspective. Costs, quality-adjusted life-years (QALYs), and the ICER in terms of 2021 US$ per QALY gained, were calculated. one-way and probabilistic sensitivity analyses were performed to evaluate the model robustness.ResultsCompared with chemotherapy, pembrolizumab increased costs by $37,201.68, while gaining 0.23 QALYs, resulting in an ICER of $163,165.26 per QALY in patients with PD-L1 CPS ≥ 10. The ICER is $202,708.62 per QALY and $163,643.19 per QALY in the total population and patients with esophageal squamous cell carcinoma, respectively. The ICER was much higher than the commonly accepted willingness-to-pay threshold ($11,105.8 per QALY). One-way and sensitivity analyses showed that the costs of pembrolizumab and the utility of PD were the crucial factors in determining the ICER, and probabilistic sensitivity analyses demonstrated pembrolizumab is unlikely to be cost-effective at a willingness-to-pay threshold of $11,105.8 per QALY. The result was robust across sensitivity analyses.ConclusionPembrolizumab is not a cost-effective treatment option for the second-line treatment of esophageal cancer from the perspective of Chinese society.
Effect of Exercise Training on Physical Fitness Among Young Tennis Players: A Systematic Review
Authors: Xiao Wensheng , Geok Soh Kim , Bai Xiaorong , Bu Te , Norjali Wazir Mohd Rozilee , Talib Othman , Liu Wenfang , Zhan Chongjiang 
Published: March 2022

BackgroundPhysical fitness comprises both health- and skill-related components that have been shown to correlate with the competitive ability of the athletes. Competitive ability of the athletes is strongly related to the positive or poor characteristics of physical fitness. Additionally, the adolescent stage is critical for the development of physical fitness. Physical fitness training for young tennis players should receive more attention. However, the current literature is deficient in in-depth reviews of the effects of exercise training on the physical fitness of young tennis players.ObjectiveThis review is aimed to investigate the effects of exercise training on physical fitness among young tennis players.MethodsFrom October 2020, a comprehensive search was undertaken in four electronic databases (SCOPUS, PubMed, EBSCOhost (SPORTDiscus), and CINAHL Plus) and also on Google Scholar and other sources of gray literature references. The methodological quality of included studies was assessed using the Physiotherapy Evidence Database scale and the over scientific evidence was determined using the best evidence synthesis (BES). This review included only studies that employed an experimental design to assess the physical fitness components of young tennis players.ResultsNine articles on exercise training met all inclusion criteria and were included in this systematic review. The studies were of a high standard of quality. The research findings are relatively credible. The results indicated that speed (n = 8) and agility (n = 8) were the most often investigated performance characteristics in exercise training interventions with young tennis players, followed by power (n = 7), strength (n = 4), and flexibility (n = 1). Exercise training significantly increased the physical fitness of young tennis players in terms of speed and agility. There is a lack of evidence about strength and flexibility. Meanwhile, there is conflicting evidence regarding the effect on power, and yet there is no evidence regarding the effect of exercise training on endurance.ConclusionsThis systematic review established a compelling case for the beneficial effects of exercise training interventions on physical fitness in youngtennis players. The review identifies current research gaps (i.e., athlete gender, with a particular emphasis on female athletes) that should be addressed in future experimental studies.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero, identifier CRD 42020213145.
Cuidar el proceso de un Grupo: Coordenadas Psicodramáticas para su comprensión
Authors: Navarro Roldán Natacha 
Published: March 2022

Se pretende poner en el centro de la reflexión el entendimiento del grupo como entramado de vínculos que generan aprendizaje sobre roles, así como su valor como ente y sistema terapéutico cuyo fin último es la salutogénesis a través del propio crecimiento y madurez. El objetivo final es permitir el crecimiento individual y tolerar la incertidumbre de su propio devenir.
Rheology of the Northern Tibetan Plateau Lithosphere Inferred from the Post-Seismic Deformation Resulting from the 2001 Mw 7.8 Kokoxili Earthquake
Authors: Lv Xiaoran , Shao Yun 
Published: March 2022

Time-series observations from Sentinel-1 A/B InSAR spanning November 2014 to July 2021 were used to study the late post-seismic deformation velocity field arising from the Kokoxili earthquake. The deformation velocity caused by the interseismic slip along the major active faults in Tibet was first simulated. Comparing the simulated deformation velocity with the observed one, the maximum ratio of the simulated deformation velocity to the observed one was found to be 42%, indicating continuity in the viscoelastic relaxation caused by the 2001 Kokoxili earthquake. Subsequently, the rheological structure of the Kokoxili region was explored using a mixed model comprising the viscoelastic relaxation mechanism and the buried elastic dislocation model. The best estimated viscosities for the lower crust and upper mantle were ηlc=1−0.44+0.78×1019 Pas and ηum=1+0+0.78×1020 Pas, respectively. The results obtained in this study were compared with those of previous studies that used the early post-seismic displacement ranging from 0 to 6.5 years following the earthquake. The obtained value was largely the same as the previously estimated steady-state viscosity, which means that the viscosities of the viscoelastic layer beneath the Kokoxili regions have almost reached their stable state. Furthermore, the effective lower crustal viscosity of the Kokoxili region exhibited a logarithmic trend with time.
Changes in the Potential Distribution of Vanilla planifolia Andrews under Different Climate Change Projections in Mexico
Authors: Armenta-Montero Samaria , Menchaca-García Rebeca , Pérez-Silva Araceli , Velázquez-Rosas Noé 
Published: March 2022

Vanilla planifolia is the most widely cultivated species for obtaining natural vanilla. In Mexico, vanilla production has decreased due to negative effects of climate change. We evaluate the current, potential, and future of vanilla cultivation areas in Mexico using bioclimatic models with distinct climate change scenarios (intermediate emissions, temperature rise of 1.1 to 2.6 °C, and high emissions from 2.6 to 4.8 °C, to 2050 and 2070), in order to understand the magnitude of future distribution changes and propose future management strategies. We found that the areas with greatest potential for establishment of V. planifolia are northern Veracruz state bordering the state of Puebla (the Totonacapan region) and northeast Oaxaca state. In the models, the most relevant environmental variable were mean temperature and precipitation of the driest quarter. The average projections for 2050 and 2070 show a progressive reduction in the potential area for the species (−1.6 and −17.3%). However, the Totonacapan region maintains the largest ideal cultivation area, while that of northeast Oaxaca is reduced by 50%. These results show the need to redesign the strategies of agricultural production of vanilla, through sustainable and climate-smart agricultural production strategies as well as a national strategy for conservation of genetic diversity.
Pemantauan Penyerapan Gas Beracun Menggunakan Tanaman Sansevieria Pada Ruangan Tertutup
Authors: Putra Barzan Trio , Exaudi Kemahyanto , Passarella Rossi , Sari Purwita 
Published: March 2022

Kualitas udara didalam ruangan perlu mendapat perhatian khusus karena sangat berpengaruh terhadap kesehatan manusia. Salah satu cara yang dapat dilakukan yaitu menjaga kualitas udara dalam ruangan tetap bersih dengan memanfaatkan tanaman sansevieria trifasciata. Penelitian ini bertujuan untuk mendeteksi kadar polusi udara didalam sebuah ruangan tertutup yang terdapat tanaman Sansevieria Trifasciata. Fungsi tanaman tersebut sebagai penyerap gas beracun seperti karbon monoksida (CO) yang tercemar didalam ruangan. Prototipe ruangan uji berukuran 65cm x 65cm x 65cm. Sensor gas diletakkan di bagian atas ruangan dan slot untuk memasukkan sampel gas dibagian depan. Sistem kerjanya adalah ruangan dilakukan strerilisasi sampai sensor gas mendeteksi nilai ppm normal, kemudian sampel gas dimasukkan kedalam ruangan uji menggunakan media suntik dan sensor gas kembali membaca nilai ppm sampai kondisi normal. Hasil penelitian membuktikan bahwa tanaman sansevieria dapat menyerap gas CO dengan sempurna. Ukuran dan bentuk sansevieria juga mempengaruhi proses penyerapan gas CO. semakin besar tanaman maka samakin baik daya serapnya. Hal ini dibuktikan dengan Rerata waktu yang dibutuhkan sansevieria kecil menyerap gas asap sampai mencapai ppm normal adalah 120 menit. Sedangkan untuk sansevieria besar selama 80 menit.
La politique censitaire du marquis de Condorcet
Authors: Guibert-Sledziewski Elisabeth 
Published: March 2022

Pourquoi la Révolution française a-t-elle entraîné la condamnation, mais aussi l'adhésion de Condorcet ? Un texte écrit par lui sur le rapport entre propriété et droits civiques peut être interrogé à ce propos :
"Sur les fonctions des Etats-Généraux, et, des autres assemblées nationales", paru en 1789. Condorcet y défend l'idée qu' "on doit regarder les propriétaires comme étant les seuls véritables citoyens". C'est au nom de la démocratie et de la lutte contre les privilèges, que sont exclus de la vie politique et du pouvoir ceux qui n'ont pas de bien. Ils ne peuvent avoir en effet le souci du bien public, et le moyen réel d'y contribuer. Condorcet révèle ici les contradictions d'une bourgeoisie qui hésite à l'alliance avec le peuple, condition nécessaire de la Révolution.
Propositions pour un enseignement de la traduction orale en laboratoire de langues
Authors: Franchéo Marianne 
Published: March 2022

Comment peut-on acquérir de façon rationnelle, efficace et individuelle une certaine technique de la traduction orale ?
Partant d'une situation pédagogique concrète combinée avec des exigences spécifiques, nous essayons d'augmenter les capacités linguistiques en utilisant le laboratoire de langues ainsi que des séries d'exercices progressifs en vue d'un but précis..
Conte ou Mythe ? Apulée : Métamorphoses (IV. § XXVIII à VI. § XXIV)
Authors: Brossard Michèle 
Published: March 2022

Une lecture naïve permet de reconnaître de nombreux traits des contes populaires dans l'histoire de Psyché et Cupidon Insérée par Apulée dans son roman Les Métamorphoese (IV § XXVIII, VI § XXIV).
Ce texte offre un champ tout désigné pour mettre è l'épreuve le modèle proposé par Vladimir Propp dons sa Morphologie du Conte. L'étude des fonctions selon la méthode de Propp permet de faire ressortir qu'il s'agit d'un conte populaire.
Les renseignements recueillis è l'issue d'une analyse menée selon cette méthode soulignent l'intérêt qu'elle offre pour l'étude d'un texte de cette nature et permettent par ailleurs de proposer, après une comparaison avec le mythe d'Isis, un essai d'interprétation du sens caché d'un conte où la fonction mythique, originelle se laisse encore exhiber.
L'anneau (ou le centre inhabitable). Mythe et cosmos de Richard Wagner
Authors: Fricheau Catherine 
Published: March 2022

Qu'y a-t-il dans l'Anneau de Nibelung ? Quel monde Wagner a-t-il enfermé dans le cercle merveilleux ?
Avec quoi a-t-il fabriqué son mythe ? Avec des "petits boutons de chemise", des grains solides qui résistent è la représentation et à l'Interprétation.
On entre dans le monde, on ne le transpose pas. Sa réalité est unique, comme est unique le langage qui la dit. Le dédoublement rend aveugle et sourd. Siegfried échoue lorsqu'il essaye d'imiter le chant des mésanges sur un roseau taillé. Il n'y a qu'un seul monde et qu'un seul langage : une seule musique. Il reste alors à décrire toutes les réalités qui composent le monde. Pour cela nous avons procédé par montage d'éléments empruntés à l'Opéra lui-même, aux contes romantiques allemands, à la poésie scaldique, aux légendes grecques et aux coutumes populaires, afin de réunir le plus d'images, le plus de sensations, le plus d'expériences possibles.
Évolution historique de la notion d'élément chimique
Authors: Sadoun Goupil Michelle 
Published: March 2022

La noción de elemento es una de las bases de la química, cuya presentación a menudo plantea problemas al cuerpo docente, y cuya adquisición siempre resulta dificultuosa. El examen de la evolución histórica de esta noción ha de ayudar, en cierta medida, a comprender mejor las dificultades halladas por los principiantes, y, por lo tanto, a resolverlas.
En esta relación haremos todo lo posible para presentar claramente y sin deformarlas las ideas expresadas a ese respecto por los que nos precedieron ; estas mismas ideas se integran en grandes corrientes de pensamiento, dentro de las cuales ha evolucionado la noción para llegar hasta nosotros.
Difficultés de compréhension en électronique élémentaire
Authors: Gillet Bernard 
Published: March 2022

Cet article rend compte d'un travail effectué auprès de 80 élèves de Classes Terminales d'électronique de la Région Parisienne. Ils ont été interrogés par entretien lors de la résolution d'exercices scolaires habituels : élaboration et traitement d'équations (celle de la maille d'un circuit électrique simple et celle de la droite de charge), de graphiques, de schémas et de montages. L'article propose d'abord un langage pour décrire d'une part les processus attendus dans l'exécution de la tâche et d'autre part le déroulement même des raisonnements observés (buts, tactiques, vérifications).
Après l'exposé de la cotation des résultats et une évaluation quantitative de l'importance des erreurs, les difficultés des élèves sont présentées à travers le cadre d'analyse des conduites observées et ce, pour chaque sorte de données successivement (équations, graphiques, schémas, montages).
Sur l'intérêt d'une nouvelle présentation de la Thermodynamique
Authors: Tonnelat Jacques 
Published: March 2022

En la física, el recurso a modelos matemáticos permite utilizar modos de razonamientos mas potentes, pero tal tipo de modelo no se adapta necesariamente mejor a la explicación de un fenómeno físico que un modelo fenomenológico.
Los modelos que suelen ser utilizados en termodinamica clasica y en
termodinámica de los fenómenos irreversibles son motivos de discusión.
En los informes habituales de termodinámica estadística, la introducción prematura de un modelo matemático disimula los trastornos sucesivos relacionados con el aumento de entropía. La toma en consideración de un modelo puramente fenomenologico const i tu i do por entidades susceptibles de transformación durante la evolución lleva a concluir que un si stoma cerrado y aislado se encamina hacia estados de equilibrio instantáneos sucesivos que pueden ser realizados de modos cada vez más numerosos. Este enunciado de la ley de evolución es mas general que el enunciado habitual que sólo toma en cuenta el aumento de entropía. Su explotación es más fructuosa en el caso de sistemas naturales. Resulta que hay que distinguir las posibilidades de reparticiones en el espacio y las posibilidades de reparticiones én los niveles de energía. Estas últimas intervienen solas en la relación dS = dQ/T. Un sistema que evoluciona se encamina hacia un estado más probable en el sentido estadístico, y no hacia un estado de energía más baja. Ademas, es de notar que no existe vinculo necesario entre entropía y desorden, ni vínculo alguno entre entropía e información .
Nixonland U.S.A.
Authors: Nataf Valérie 
Published: March 2022

Confier à Nixon le rôle du narrateur privilégié dans une œuvre contemporaine, tel est le pari de Coover. Ce choix conditionne une écriture dont notre étude se propose de cerner les enjeux.
En premier lieu, il s’agit d’examiner l’esthétique du discontinu qui s’exprime à la fois au niveau structurel et dans l’écriture fantasmatique. Il en résultera une tension entre le réel et l’imaginaire. Nixon métaphorisera ce processus dont nous analyserons les deux étapes : le «brouillage» et la contamination.
Ensuite, nous constaterons l’effet produit par ce décalage entre la vérité historique et la fiction. C’est, bien sûr, le rire dont les manifestations diverses révèlent autant de points de vue de Coover quant à l’idéologie américaine.
Celle-ci fournira la matière à notre troisième problématique. En effet, Nixon s’avère être le véhicule des métaphores religieuse et spectaculaire dans le roman. Nous en étudierons les fonctionnements spécifiques dans le cadre d’une certaine nixonisation de l’Amérique, c’est-à-dire d’une emblématisation symptomatique des années cinquante.
La ville en propre. La police des rues à Paris aux XVIIe et XVIIIe siècles
Authors: Houdard Sophie 
Published: March 2022

Las calles de la Capital limpias y seguras : esta orden dirigida a los parisienses a mediados del siglo XVII es el punto de partida de este estudio. La limpieza de la ciudad es asunto de la Policía, lo “sucio" entra en el campo de la penalidad y de la seguridad pública, cuando los criterios medicales estabilizan las normas de la limpieza y del bienestar.
En este trabajo se analizan las relaciones que permitieron la creación y el desarrollo de prácticas - institucionales y privadas - de limpieza, la emergencia de una nueva sensibilidad en las personas, la aparición en los textos y en el mapa de la ciudad de una geografía moral de la limpieza y de la suciedad.