bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlating Perceptual Voice Quality in Adductor Spasmodic Dysphonia With Computer Vision Assessment of Glottal Geometry Dynamics
Authors: Peterson Quinn A. , Fei Teng , Sy Lauren E. , Froeschke Laura L.O. , Mendelsohn Abie H. , Berke Gerald S. , Peterson David A. 
Published: September 2022

Purpose:
This study examined the relationship between voice quality and glottal geometry dynamics in patients with adductor spasmodic dysphonia (ADSD).

Method:
An objective computer vision and machine learning system was developed to extract glottal geometry dynamics from nasolaryngoscopic video recordings for 78 patients with ADSD. General regression models were used to examine the relationship between overall voice quality and 15 variables that capture glottal geometry dynamics derived from the computer vision system. Two experts in ADSD independently rated voice quality for two separate voice tasks for every patient, yielding four different voice quality rating models.

Results:

All four of the regression models exhibited positive correlations with clinical assessments of voice quality (
R
2
s = .30–.34, Spearman rho = .55–.61, all with
p
< .001). Seven to 10 variables were included in each model. There was high overlap in the variables included between the four models, and the sign of the correlation with voice quality was consistent for each variable across all four regression models.

Conclusion:
We found specific glottal geometry dynamics that correspond to voice quality in ADSD.
Microstructural analysis of biowaste‐derived hydroxyapatite‐chitosan nanocomposites
Authors: Shah Sambridhi , Joshi Rajendra , Rai Nelson , Adhikari Rameshwar , Pandit Rajesh 
Published: September 2022

AbstractIn recent years, considerable attention is given in various nanomaterials development using biodegradable wastes for establishing more eco‐friendly technologies. Due to the biocompatible, biodegradable, and non‐toxic nature hydroxyapatite (HAp) and chitosan (CS) are highly studied in recent times. In this research work, HAp and CS were synthesized in a nanometric range using the bio‐wastes obtained from chicken bones and pila shells, respectively. In addition, HAp/CS nanocomposites were also prepared through the co‐precipitation method in various weight ratios. The synthesized nanomaterials and nanocomposites were characterized by X‐ray diffraction (XRD) and Fourier Transform Infrared (FTIR) spectroscopy. The XRD pattern analysis revealed the hexagonal crystalline structure of HAp and orthorhombic crystallite structure of CS with crystallite sizes of 40.52 and 39.51 nm, respectively. The physical parameters such as d‐spacing, dislocation density, stacking fault probability, and lattice strain of HAp and CS were also analyzed. The FTIR spectra analysis confirmed the formation of HAp and CS. Likewise, the broadening and weakening of the chemical bond between two phases of HAp and CS indicated the bond formation and compatibility between HAp and CS.
Kosteneffizienz der Behandlung von Aszites bei Leberzirrhose im Rahmen des G-DRG-Systems
Authors: Claus Simone , Brozat Jonathan Frederik , Trautwein Christian , Koch Alexander 
Published: September 2022

ZusammenfassungIn Deutschland sind rund 1 Mio. Menschen von einer Leberzirrhose betroffen. Eine häufige Komplikation stellt dabei das Auftreten von Aszites dar. Durch die steigende Leistungsverdichtung im Krankenhaus sowie die zunehmende Ökonomisierung im Gesundheitssektor befinden sich die Kliniken im Spannungsfeld zwischen Wirtschaftlichkeit und patientenorientierter Gesundheitsversorgung. Angesichts geringer Erlösflexibilität durch Fallpauschalen sind die Behandlungskosten ein wichtiger Ansatzpunkt der Erfolgsoptimierung und des effektiven Umgangs mit Ressourcen. Das Ziel dieser Arbeit war daher eine Aufarbeitung der Kosten- und Erlösstrukturen der Aszitesbehandlung in einem universitären Zentrum mit hepatologischem Schwerpunkt. Für diese Studie wurden die Behandlungsdaten von 778 Patienten, die im Zeitraum von 2016 bis 2019 in der Medizinischen Klinik III des Universitätsklinikums Aachen aufgenommen wurden, retrospektiv und anonymisiert ausgewertet. Die ermittelten Leistungen wurden im Rahmen einer Prozesskostenrechnung wirtschaftlich bewertet und den Erlösanteilen der Matrix aus Kostenstellen und Kostenarten des Diagnosis-Related-Groups (DRG)-Systems gegenübergestellt. Es zeigten sich Unterdeckungen in allen untersuchten Bereichen entlang des Behandlungspfades, sodass gegenwärtig die Versorgung des Aszites bei Zirrhose nicht kostendeckend im deutschen DRG-System abgebildet ist. Dies ist insbesondere auf eine höhere Fallschwere der universitär behandelten Patienten zurückzuführen.
A New Avenue to One-Pot Four-Component Synthesis of Spiro[indoline-3,4′-quinoline] Derivatives Using DABCO as a Green Catalyst
Authors: Singh Sundaram , Maury Suresh Kumar 
Published: September 2022

AbstractA simple, efficient, and green, one-pot four-component synthesis of spiro[indoline-3,4′-quinoline] derivatives has been developed from isatin, ethyl cyanoacetate/malononitrile, dimedone, and aniline using green catalyst DABCO and green solvent ethanol. The current method generates good to exceptional yields in a short reaction time and provides a broad substrate scope. This method also works for gram-scale reactions.
The Therapeutic Potential of Salidroside for Parkinsonʼs Disease
Authors: Li Li , Yao Wenlong 
Published: September 2022

AbstractParkinsonʼs disease (PD), a neurological disorder, is characterized by the progressive loss of dopaminergic (DA) neurons in the substantia nigra. Its incidence increases with age. Salidroside, a phenolic compound extracted from Sedum roseum, reportedly has multiple biological and pharmacological activities in the nervous system. However, its effects on PD remain unclear. In this review, we summarize the effects of salidroside on PD with regard to DA metabolism, neuronal protection, and glial activation. In addition, we summarize the susceptibility genes and their underlying mechanisms related to antioxidation, inflammation, and autophagy by regulating mitochondrial function, ubiquitin, and multiple signaling pathways involving NF-κB, mTOR, and PI3K/Akt. Although recent studies were based on animal and cellular experiments, this review provides evidence for further clinical utilization of salidroside for PD.
Green Tea Catechol (−)-Epigallocatechin Gallate (EGCG) Conjugated with Phenylalanine Shows Enhanced Autophagy Stimulating Activity in Human Aortic Endothelial
Cells
Authors: Lee Taegum , Oh Yeonji , Kim Mi Kyoung , Chong Youhoon 
Published: September 2022

Abstract(−)-Epigallocatechin gallate (EGCG) is one of the autophagy stimulators that have been reported to protect vascular endothelial cells from oxidative stress-induced damage. In this study, we
attempted potentiation of the autophagy-stimulating activity of EGCG in human aortic epithelial cells (HAECs) by using the EGCG-phenylalanine conjugate, E10. Autophagy-stimulating activity
of E10 was evaluated by LC3-II measurement in the absence and presence of the lysosomal blocker chloroquine, CTYO-ID staining, and reporter assay using tandem fluorescence-tagged LC3. These
experiments revealed significantly enhanced autophagic flux stimulation in HAECs by E10 compared with EGCG. Further elaboration of E10 showed that activation of AMPK through phosphorylation
as the major mechanism of its autophagy stimulation. Like other autophagy stimulators, E10 protected HAECs from lipotoxicity as well as accompanying endothelial senescence. Finally,
stimulation of autophagy by E10 was shown to protect HAECs from oxidative stress-induced apoptosis. These findings collectively suggest potential clinical implications of E10 for various
cardiovascular complications through stimulation of autophagy.
Enantioselective Alkylation of Amino Acid Derivatives with ­Unactivated Olefins via C–N Bond Cleavage
Authors: Shang Ming , Cai Yue-Ming 
Published: September 2022

AbstractWe reported a nickel-catalyzed enantioconvergent deaminative alkylation of α-amino acid derivatives with unactivated olefins, providing an efficient and convenient access to a range of α-enantioenriched amides. This method represents the first example of enantioselective deaminative functionalization with racemic amine precursors and features in mild conditions and broad substrate scope. New sterically encumbered bis(oxazoline) ligand was developed to improve both reactivity and enantioselectivity, which is key to the success of this reaction.
Comparison of Hindlimb Conformation in Cats with and without Medial Patellar Luxation
Authors: Beer Andrew James Carey , Langley-Hobbs Sorrel , Belch Alex 
Published: September 2022

Abstract
Objectives Medial patellar luxation (MPL) is the most common developmental cause of hindlimb lameness in cats. The association between femoral and tibial conformation and MPL measured on computed tomography (CT) has not been reported in cats. The aims were to report femoral and tibial conformation in cats with and without MPL and to report normal femoral and tibial angles.
Methods Angle of inclination of femoral neck (AI), anatomical lateral distal femoral angle (aLDFA), femoral trochanteric angle (FCT), angle of anteversion of femoral neck (AA), distal and proximal anteversion angle (DAA/PAA), overall tibial valgus (TV), tibial torsion (TT), tibial tuberosity displacement (TTD) and trochlear depth:patellar thickness ratio (T:P) were measured by three observers on CT of cats with and without MPL. Comparisons were made between groups. Inter-observer intraclass correlation coefficient (ICC) was calculated.
Results Sixteen cats were recruited: eight control and eight with MPL. The aLDFA, PAA, TT, TTD and T:P were significantly less in cats with high-grade MPL. The AI, FCT, AA, DAA and TV were not significantly different. A high correlation was shown with inter-observer ICC in 33.33% and good correlation in 26.67% when comparing measurements between observers.
Clinical Significance This study suggests that cats with high-grade MPL have decreased TT, TTD and T:P and may require tibial tuberosity transposition and femoral trochleoplasty. The PAA, TT and aLDFA were decreased, although clinical significance may vary and these cats may not require correctional osteotomies. Results should be interpreted with caution as high/good levels of inter-observer ICC occurred in less than two-thirds of cases between observers.
A lexicon-based approach to examine depression detection in social media: the case of Twitter and university community
Authors: Cha Junyeop , Kim Seoyun , Park Eunil 
Published: September 2022

AbstractGlobally, the number of people who suffer from depression is consistently increasing. Because both detecting and addressing the early stage of depression is one of the strongest factors for effective treatment, a number of scholars have attempted to examine how to detect and address early-stage depression. Recent studies have been focusing on the use of social media for depression detection where users express their thoughts and emotions freely. With this trend, we examine two-step approaches for early-stage depression detection. First, we propose a depression post-classification model using multiple languagesTwitterdatasets (Korean, English, and Japanese) to improve the applicability of the proposed model. Moreover, we built a depression lexicon for each language, which mental health experts verified. Then, we applied the proposed model to a more specific user group dataset, a community of university students (Everytime), to examine whether the model can be employed to address depression posts in more specific user groups. The classification results present that the proposed model and approach can effectively detect depression posts of a general user group (Twitter), as well as specific user group datasets. Moreover, the implemented models and datasets are publicly available.
Use of Recovery Probabilities Can Improve Sampling Efficiency for Throw Traps in Vegetated Habitats
Authors: Camp Edward V. , Gwinn Daniel C. , Lauretta Matthew V. , Pine William E. , Frazer Thomas K. 
Published: September 2022

AbstractThrow traps are commonly used to assess small fish and macroinvertebrate (SFI) communities in aquatic habitats. Traditionally, numerous passes with a bar seine are used to remove all SFIs from within the throw trap, providing density estimates that are comparable across habitat types. However, similar information can be gathered with fewer seine passes than are traditionally used, thus allowing more sampling in a given field effort. The appropriate number of seine passes to meet study objectives can be determined if habitat‐specific recovery probabilities are estimated. We investigated how SFI recovery probabilities within throw traps varied among five submerged aquatic vegetation habitat types and how these recovery probabilities can be used to determine the number of seine passes necessary to assess and detect differences in SFI relative abundance. Using a 1‐m2 throw trap and bar seine, we found that estimates of SFI recovery probability were high (75–80%) and similar across habitats. Because of the high recovery probabilities, the use of about three bar‐seine passes produced accurate estimates of true SFI density within a throw‐trap sample, and additional bar‐seine passes did not substantially improve the power to detect decreases in SFI density. These results are applicable to studies that use throw traps to sample SFIs in submerged aquatic vegetation habitats, and they illustrate how improvements in sampling efficiency can be obtained by decreasing the number of passes used per sample.
Culture of Tubifex tubifex: Effect of Feed Type, Ration, Temperature, and Density on Juvenile Recruitment, Production, and Adult Survival
Authors: Oplinger Randall W , Bartley Matt , Wagner Eric J 
Published: September 2022

Abstract
The oligochaete worm Tubifex tubifex is widely cultured as a fish food. Stocking of certain T. tubifex strains has been shown to help prevent the occurrence or reduce the severity of whirling disease caused by Myxobolus cerebralis. Optimal culture conditions (e.g., temperature, density, and feed type) are not known for T. tubifex. We conducted four experiments to improve our knowledge of culture methods for T. tubifex. First, we evaluated the survival, growth, and recruitment of T. tubifex that were fed one of three different diets. We found that the performance of worms fed cow manure was poor and that growth and recruitment were best when they were fed either a commercial fish-flake food (Tetramin) or a commercial sinking fish feed containing spirulina Spirulina spp. In the second experiment, we evaluated the performance of worms fed Tetramin at rations of 0, 2.5, 5.0, and 10.0% of body mass/d and found the greatest growth and recruitment at the 5.0% and 10.0% rations. In the third experiment, we found high growth and survival among T. tubifex at temperatures between 12°C and 27°C; however, recruitment decreased at temperatures above 21°C. In the final experiment comparing seven initial adult stocking densities (2,675–267,451 individuals/m2), juvenile recruitment and the net increase in biomass were found to be highest at the lowest initial density of 2,675 adults/m2. Recruitment decreased significantly at densities above 6,686 adults/m2.
Received June 16, 2010; accepted September 4, 2010
Laboratory Mass Culture of the Freshwater Oligochaete Dero digitata
Authors: Mischke Charles C , Griffin Matt J 
Published: September 2022

Abstract
Proliferative gill disease (PGD) in channel catfish Ictalurus punctatus is caused by the myxozoan parasite Henneguya ictaluri, which uses the freshwater oligochaete Dero digitata as an alternate host. Controlled studies on the transmission of PGD require sustainable D. digitata mass cultures. We developed methods to grow and sustain large D. digitata populations and compared population growth in aerated versus nonaerated containers. White paper towels (2–3-cm squares) were placed into six 10.7-L dish pans into which 4 L of autoclaved pond water from commercial channel catfish ponds were then added along with 0.1 g of fish food. Each of the six dish pans was initially stocked with 100 D. digitata and maintained at 22–25°C; three pans received aeration, and three did not. All worms were counted and returned to their respective pans once each week for 5 weeks. To compensate for evaporative loss, autoclaved pond water was added to the pans weekly, and pond water and paper towels were completely changed after 4 weeks. Over 5 weeks, the mean number of worms per pan increased significantly more in the nonaerated pans than in the aerated pans. We have maintained D. digitata mass cultures in our laboratory for over a year, starting with two pans containing 100 worms each. Through routine exchanges of pond water and paper towel squares, these populations have expanded to 16 pans, each supporting 3,000–6,000 worms. We have also removed thousands of worms periodically to give to other researchers or for research in our laboratory. Using methods described here, researchers can maintain D. digitata mass cultures and predict population numbers that will be available at given times for studies on myxozoan life cycles and oligochaete control.
Received March 12, 2010; accepted May 24, 2010
Effects of the COVID-19 lockdowns on aesthetic and affective evaluations of natural and urban scenes (Efectos de los confinamientos COVID-19 sobre las evaluaciones estéticas y afectivas de escenas naturales y urbanas)
Authors: Felisberti Fatima-M. , Harrison Neil-R. 
Published: September 2022

The ongoing COVID-19 pandemic and subsequent UK lockdowns restricted mobility, altered access to the outdoors and led to changes in the environment (e.g., reduced traffic, pollution and crowding). This is likely to have altered the way people evaluated outdoor environments. Here we investigated aesthetic and emotional responses (liking, openness, relaxation) to paintings and photographs depicting landscapes and urban scenes in three UK cohorts: pre-lockdown, spring 2020 lockdown, and winter 2021 lockdown. Participants ( N = 334) reported higher levels of liking, openness and relaxation for landscapes and urban scenes during the two lockdown periods compared to pre-lockdown levels. Importantly, evaluations in the lockdown groups were influenced by the types of places visited most frequently. These findings aid our understanding of the psychological effects of lockdowns on evaluations of outdoor environments and are relevant to the development of policies for the promotion of well-being, including the design of more open and relaxing urban spaces.
Spin excitations of individual magnetic dopants in an ionic thin film
Authors: Li Zhe , Delgado Fernando , Du Mei , He Chen , Schouteden Koen , Haesendonck Chris Van , Janssens Ewald , Arnau Andres , Lievens Peter , Cerda Jorge I 
Published: September 2022

Abstract
Individual magnetic transition metal dopants in a solid host usually exhibit relatively small spin excitation energies of a few meV. Using scanning tunneling microscopy and inelastic electron tunneling spectroscopy (IETS) techniques, we have observed a high spin excitation energy around 36 meV for an individual Co substitutional dopant in ultrathin NaCl films. In contrast, the Cr dopant in the NaCl film shows much lower spin excitation energy around 2.5 meV. Electronic multiplet calculations combined with first-principles calculations confirm the spin excitation induced IETS, and quantitatively reveal the out-of-plane magnetic anisotropies for both Co and Cr. They also allow reproducing the experimentally observed redshift in the spin excitations of Co dimers and ascribe it to a charge and geometry redistribution.
An attention-enhanced multi-modal deep learning algorithm for robotic compound fault diagnosis
Authors: Zhou Xing , Zeng Hanlin , Chen Chong , Xiao Hong , Xiang Zhenlin 
Published: September 2022

Abstract
Compound fault diagnosis plays a critical role in lowering the maintenance time and cost of industrial robots. With the advance of deep learning and industrial big data, a compound fault diagnosis model can be established through a data-driven approach. However, current methods mainly focus on the single fault diagnosis of assets, which cannot achieve satisfactory performance for compound fault diagnosis. This study proposes a compound fault diagnosis algorithm for an industrial robot based on multi-modal feature extraction and fusion. Firstly, the multi-head self-attention enhanced convolution neural network module and long short-term memory network module are adopted to learn the fault-related features from different perspectives simultaneously. The local and global features extracted by the aforementioned modules are then fused for subsequent compound fault classification. An experimental study was implemented based on real-world robotic sensor data. The experimental results indicated that the proposed multi-modal algorithm shows merits in compound fault diagnosis in comparison with other state-of-the-art methods.
A simple experimental setup for investigating light diffraction with a thin copper wire and a LED
Authors: Onorato Pasquale , Gratton Luigi M , Di Mauro Marco , Rosi Tommaso 
Published: September 2022

Abstract
A simple experimental setup for quantitatively investigating single-slit diffraction is described, which uses only inexpensive materials and can be reproduced at home, making it suitable for distance learning. The theoretical basis exploits Babinet’s principle, according to which a thin wire—much easier to obtain than a slit—produces, with a very good approximation, a diffraction pattern which is the same as that produced by the slit. A copper wire is placed directly on the camera of a smartphone, and the resulting photos are quantitatively analyzed with Tracker. As light sources, LEDs of different colors are used.
Grüneisen approach for universal scaling of the Brillouin shift in gases
Authors: Liang Kun , Xu Jiaqi , Wang Yuanqing , Lü Hai-Feng , Ubachs Wim 
Published: September 2022

Abstract
A Grüneisen relationship is defined for gases, following the formulation of the original microscopic Grüneisen ratio γ = (d ln ω)/(d ln V) for solids. In the case of gases acoustic excitations represent the modes at frequency ω to be considered. By comparing to measured Brillouin shifts in various gases (SF6, N2O, and CO2) under various conditions of pressure and temperature, a specific value of the defined ratio γ
0 = 0.064 ± 0.004 is found to provide a universal description of the active modes in a gas. This finding of such universal gas law may find application in extrapolation of properties of ideal gases to regimes where those cannot be measured easily, like the acoustics and shocks at extremely high temperatures.