bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interspecific competition can drive the loss of conjugative plasmids from a focal species in a microbial community
Authors: Walker-Sünderhauf David , Klümper Uli , Gaze William H , Westra Edze R , van Houte Stineke 
Published: June 2022

AbstractPlasmids are key disseminators of antimicrobial resistance genes and virulence factors, and it is therefore critical to predict and reduce plasmid spread within microbial communities. The cost of plasmid carriage is a key metric that can be used to predict plasmids’ ecological fate, and it is unclear whether plasmid costs are affected by growth partners in a microbial community. We carried out competition experiments and tracked plasmid maintenance using a synthetic and stable 5-species community and a broad host-range plasmid as a model. We report that both the cost of plasmid carriage and its long-term maintenance in a focal strain depended on the presence of competitors, and that these interactions were species-specific. Addition of growth partners increased the plasmid cost to a focal strain, and accordingly plasmid loss from the focal species occurred over a shorter time frame in these species combinations. We propose that the destabilising effect of interspecific competition on plasmid maintenance may be leveraged in clinical and natural environments to cure plasmids from focal strains.
Identification of genomic regions implicated in susceptibility toSchistosoma mansoniinfection in a murine genetic model (backcross)
Authors: Hernández-Goenaga Juan , López-Abán Julio , Blanco-Gómez Adrián , Vicente Belén , Burguillo Francisco-Javier , Pérez-Losada Jesús , Muro Antonio 
Published: June 2022

AbstractHigh levels of infection and severe liver fibrosis in schistosomiasis appear only in a few cases of infected people with high susceptibility. Tissue damage is caused by the inflammatory response to eggs trapped in the liver. The genetic background influences susceptibility to schistosome infection. To assess the genetic basis of susceptibility to schistosomiasis and identify the chromosomic regions involved, we used a backcross strategy to generate a mouse cohort with high variation in schistosomiasis susceptibility. Thus, we crossed the resistant C57BL/6 mouse strain with the susceptible CBA one; and later; the F1 females (C57 x CBA) were backcrossed with CBA males generating the F1BX cohort. The spectrum of phenotypes in the F1BX mice showed gradation from mild to severe disease, lacking a fully resistant group. We differentiated four levels of infection intensity using cluster and principal component analyses and K-means based on parasitological, pathological and immunological trait measurements. Mice were massively genotyped with 961 informative SNPs. We identify 19 new quantitative trait loci (QTL) associated with phenotype indicators of parasite burden, liver lesion, white blood cell populations, and antibody responses evaluated in the backcross cohort. Two QTLs on chromosomes 15 and 18 were simultaneously linked to the number of granulomas, grade of liver lesion and IgM levels. The human syntenic regions are located in chromosomes 8 and 18. None of the significant QTL identified coincided with previously reported mice association or were syntenic with human chromosomes.Author summaryHigh number of cases of infection and high levels of infection and liver fibrosis in schistosomiasis appear only in a few cases of people with high susceptibility, because the genetic background influences this susceptibility. To assess this, we used a backcross strategy crossing a resistant strain of mouse C57BL/6 with another susceptible CBA, and later F1 females were backcrossed with males susceptible, generating the F1BX cohort, which showed gradation from mild to severe disease. We differentiated four levels of infection according to cluster, principal component analysis and K-means, and based on parasitological, pathological and immunological measurements. Mice were massively genotyped and 19 quantitative trait loci (QTL) were identified, associated with phenotype indicators evaluated in backcross cohort. Two QTLs on chromosomes 15 and 18 were simultaneously linked to the number of granulomas, grade of liver lesion and IgM levels. None of the significant QTL identified coincided with previously reported mice association or were syntenic with human chromosomes.
Exact solutions of (1+2)-dimensional non-linear time-space fractional PDEs
Authors: Kumar Manoj 
Published: June 2022

PurposeIn this paper, the author presents a hybrid method along with its error analysis to solve (1+2)-dimensional non-linear time-space fractional partial differential equations (FPDEs).Design/methodology/approachThe proposed method is a combination of Sumudu transform and a semi-analytc technique Daftardar-Gejji and Jafari method (DGJM).FindingsThe author solves various non-trivial examples using the proposed method. Moreover, the author obtained the solutions either in exact form or in a series that converges to a closed-form solution. The proposed method is a very good tool to solve this type of equations.Originality/valueThe present work is original. To the best of the author's knowledge, this work is not done by anyone in the literature.
Opportunities and challenges for service-learning experiences in informal urban settlements
Authors: Garcia Cervantes Natalia , Hinojosa Hinojosa Karen 
Published: June 2022

PurposeThe purpose of this article is the discussion of a service-learning experience in architecture pedagogy, based on two core courses at a private university in Mexico. The aim is to identify learning opportunities, challenges and implications arising from engaging with inhabitants of an informal urban settlement with limited digital resources in La Campana-Altamira in Monterrey, Mexico.Design/methodology/approachThe methodology selected is a case study approach, chosen for its effectiveness in architectural pedagogy to create knowledge through exposure to a particular phenomenon, as well as highlight positive teaching practices to facilitate replicability. Case-study methodology was also beneficial in this case because its openness and flexibility allowed for research of a variety of phenomena simultaneously, in this case, both the effects in the informal settlement community and in the academic one.FindingsFindings revealed that opportunities outweigh challenges, and meaningful service and learning are possible in an online context, even when the service aspects take longer than the course length if there are long-term relationships between communities and institutions.Originality/valueThe value of the article lies in the need for flexible and sensitive approaches that put communities in the center, a critical path to identifying and understanding their needs and improving their contexts. This holds especially true given the rapid pace of worldwide urbanization and the ubiquity of informal urban settlements. Implementing service-learning approaches in informal settings using online tools, while sanitary restrictions are in place shows that meaningful experiences can be achieved, even when courses are short and resources are limited.
Improving smallholder farmer's soil nutrient management: the effect of science and technology backyards in the North China plain
Authors: Li Fan , Li Dangui , Voors Maarten , Feng Shuyi , Zhang Weifeng , Heerink Nico 
Published: June 2022

PurposeSoil nutrient management and fertilizer use by farmers are important for sustainable grain production. The authors examined the effect of an experimental agricultural extension program, the science and technology backyard, in promoting sustainable soil nutrient management in the North China Plain (NCP). The science and technology backyard integrates farmer field schools, field demonstrations, and case-to-case counselling to promote sustainable farming practices among rural smallholders.Design/methodology/approachThe authors conducted a large-scale household survey of more than 2,000 rural smallholders. The authors used a multivariate regression analysis as the benchmark to assess the effect of the science-and-technology backyard on smallholder soil nutrient management. Furthermore, the authors used coarse exact matching (CEM) methods to control for potential bias due to self-selection and the (endogenous) switching regression approach as the main empirical analysis.FindingsThe results show that the science-and-technology backyard program increased smallholders' wheat yield by approximately 0.23 standard deviation; however, no significant increase in maize yield was observed. Regarding soil nutrient use efficiency, the authors found a significant improvement in smallholders' phosphorus and potassium use efficiencies for both wheat and maize production, and a significant improvement in nitrogen use efficiency for wheat production, but no significant improvement of nitrogen use efficiency for maize production.Originality/valueThis study evaluated a novel participatory agricultural extension model to improve soil nutrient management practices among smallholders. The integration of agronomists' scientific knowledge and smallholders' local contextual experiences could be an effective way to improve farmers' soil nutrient management. This study provides the first quantitative estimates based on rigorous impact assessment methods of this novel extension approach in rural China.
Exploring the influence of tourist ethnocentrism and risk perception on the hospitality and tourism industry
Authors: Bremser Kerstin , Abraham Villy 
Published: June 2022

PurposeRisk perception and ethnocentrism are recognized as significant psychological factors influencing tourism behaviors. However, the impact of tourist ethnocentrism (TE) on tourism and hospitality-related behaviors has mainly been overlooked in previous research. Hence, the objective of the present study is to propose a comprehensive TE model by exploring the influence of TE and risk perception on the domestic hospitality and tourism industry in Israel.Design/methodology/approachA convenience sample of 204 Israeli respondents 18 years of age or older took part in the study. Structural equation modeling (SEM) was employed to assess hypothesized relationships in the proposed model.FindingsThe data confirmed five out of the eight hypotheses tested. The study findings suggest that TE is unrelated to willingness to pay (WTP) a price premium for local travel or dine in local restaurants. Similarly, the authors found no association between risk perception and willingness to dine in local restaurants.Originality/valueThe current investigation contributes to the literature by proposing a model conceptualizing the influence of both TE and risk perception on hospitality (i.e. dine in a local restaurant) and tourism (i.e. domestic travel). The present research findings contribute to the tourism ethnocentrism literature and shed new light on social identity theory (SIT) by pointing to the importance of considering value for money in future conceptualizations and suggest monetary considerations may overshadow other in-group considerations as conceptualized in SIT.
Social franchise chains operating in African countries: are their social goals aligned with the 2030 United Nations sustainable development goals?
Authors: Perrigot Rozenn , Elom Gbetchi Komlanvi 
Published: June 2022

PurposeSocial franchise chains have social goals rather than – or in addition to – commercial or profit-making goals. But are these social goals, disclosed by social franchisors, aligned with the Sustainable Development Goals (SDGs) and, if so, which ones?Design/methodology/approachThe authors examine the disclosure of SDG-related information on websites of 69 social franchise chains operating in Africa.FindingsThe authors' main findings show that social goals disclosed by social franchisors are aligned with certain SDGs that are general in nature and not just sector-dependent, except in the case of education.Practical implicationsThe authors' paper contributes to the practice by providing examples of the types and varieties of social goals social franchisors can pursue. Moreover, entrepreneurs might be encouraged to launch their franchise concept as franchisors who contribute to SDGs at an international, national or regional level or to join franchise chains as franchisees who contribute to SDGs at the local level.Social implicationsThe authors' findings show the potential for social franchise chains in developing countries to target and contribute to achieving SDGs.Originality/valueThe authors' paper adds to the limited literature on SDGs and, more specifically, on the role of the private sector, in particular social franchisors, in targeting and achieving SDGs.
Hindrances to smart tourism development
Authors: Sun Sunny , Ye Huiyue , Law Rob , Hsu Alex Yang-Chan 
Published: June 2022

Purpose
Most previous studies have discussed the factors that drive the development of smart tourism or its benefits. Nevertheless, hindrances to smart tourism development have been largely ignored by previous studies. Hence, to bridge the aforementioned research gap, the present study identified the hindrances to smart tourism development in Hong Kong, which has been affected by the recent pandemic, based on the adjusted destination competitiveness conceptual models.

Design/methodology/approach
The purpose of this study is to investigate the hindrances to smart tourism development. A qualitative interview method using a semi-structured questionnaire with open-ended questions was adopted in the present study.

Findings
Findings of the present study indicated that the hindrances in developing smart tourism in Hong Kong are from four primary perspectives, namely, economic, sociocultural, technological and planning and management.

Research limitations/implications
Seeking cooperation from popular tourist destinations can address the economic issues of market size and return on investment in technological infrastructure. Experiences, as the core product of travel, should be highlighted in smart tourism development and enterprises should be given support for the transformation.

Originality/value
Theoretically, based on the adjusted conceptual models for destination competitiveness, the present study identifies the macro factors that hinder the development of smart tourism in Hong Kong from different primary perspectives. Practically, factors such as policy support, which includes public funding or low-interest loans, are essential to supporting preliminary finances to attract entrepreneurs and young talents to participate in the development.
Marketing's take on socio-economic performance
Authors: von der Osten Flávio Luiz , Toaldo Ana Maria 
Published: June 2022

PurposeThe purpose of this paper is to propose that a stakeholder orientation (SO) can explain social and economic performances. It happens because the more the organisation acquires and disseminates stakeholder intelligence, the more it will be aware of the needs of different stakeholder groups, bending the decision making towards less powerful stakeholders and creating social performance. At the same time, more stakeholder intelligence is a strategic resource to be exploited favouring the economic performance. Moreover, it is proposed this effect is mediated by social motivations.Design/methodology/approachIn all, 251 Brazilian agricultural cooperatives were sampled and a survey primary data collection method was applied. To test our hypothesis, the partial least squares structural equation modelling method is used.FindingsIt is found that SO positively influences social and economic performances. Social motivation mediates the relationship between SO and social performance.Originality/valueSocial performance has gained importance because strategies harmful to society are not acceptable anymore and because of the link with economic performance. However, the strategic marketing literature is still scant on how marketing can drive economic and social performance at the same time.
Suicide clusters in law enforcement: a descriptive analysis
Authors: Violanti John M. 
Published: June 2022

PurposeThis study examined the national prevalence of cluster suicides among law enforcement personnel at the county level, the influence on future suicides and risk factors associated with clusters.Design/methodology/approachLaw enforcement suicide data were obtained from The National Violent Death Reporting System (NVDRS) and categorized into: (1) cluster and (2) non-cluster suicides. Chi-square was used to compare differences between the two groups. Logistic regression was used to predict the probability of suicide risk factors in the groups.Findings2,465 law enforcement suicides were listed in NVDRS between 2003–2018. 80 (9.4%) US counties had clusters, with 640 officers (25.7%) of officers as part of those clusters. Odds ratios for risk factors associated with the suicide cluster group were: mental health crisis (OR = 2.6,p = 0.026), age (OR = 1.01,p = 0.003), married (OR = 1.729,p=<0.001), military service (OR = 2.59,p=<0.001) and job problems (OR = 1.70,p = 0.05).Research limitations/implicationsThis study suggests that cluster suicides occur in law enforcement. The study is primarily descriptive and limited by the different numbers of contributing states in the NVDRS database through the years.Practical implicationsThis study suggests that clusters occur in law enforcement and that they can impact future suicides. It is important for law enforcement organizations to recognize the potential for suicide clusters.Originality/valueThis study is among the first to empirically examine suicide clusters in law enforcement.
Role of information and communication technology in mitigating risks in Indian agricultural supply chains
Authors: Shukla Suwarna , Kapoor Rohit , Gupta Narain , Garza-Reyes Jose Arturo , Kumar Vikas 
Published: June 2022

Purpose
Theorising from a resource-based view perspective, the intersection of supply chain management and the use of information technology (IT) has been investigated in this study. This paper aims to investigate supply chain performance (SCP) as an essential outcome of the use of IT and explores the effect of supply chain collaboration (SCC) on SCP. In addition, volume uncertainty (VU) has been explored and tested to establish whether various associated uncertainties can be mitigated when the use of IT is involved.

Design/methodology/approach
A sample of 121 senior executives from agri-tech firms was collected by travelling and meeting the executives in person in various states of India. Structural equation modelling was used to test the hypothesized relationship of VU to SCP via the use of IT and SCC.

Findings
The results show that VU significantly impacts SCC via the use of IT and SCP via SCC. The use of IT positively and significantly impacts SCP via SCC.

Practical implications
Witnessing the potential benefits of the emerging use of IT in the uncertainty reduction as reported in this study, agri-tech firms operating in emerging rural and agricultural economies can enhance SCC to improve SCP.

Social implications
This study unfolds how risks in agricultural supply chains (ASCs) sourced because the VU can be mitigated through the use of IT and SCC to influence SCP in rural agricultural and developing economies.

Originality/value
VU at agri-tech firms and farmers is a ground reality that has led to an inability to plan and prepare, resulting in wastages and disruptions in ASCs and farmers’ struggles.
Applicability of cross‐property differential effective medium model to the joint elastic–electrical properties of reservoir sandstones
Authors: Han Tongcheng , Yan Han , Fu Li‐Yun , Li Fulai 
Published: June 2022

ABSTRACTJoint seismic and controlled‐source electromagnetic surveys can reduce uncertainty and improve hydrocarbon quantification. However, the successful interpretation of joint seismic and controlled‐source electromagnetic survey data requires a valid rock physics model to link the elastic and electrical rock properties. A cross‐property differential effective medium is recently proposed with pores embedded in the mineral matrix. We have presented a technique to test the applicability of the cross‐property differential effective medium model to the joint elastic‐electrical properties of reservoir sandstones. The method is based on the common employment of measured sample porosity and inverted equivalent pore aspect ratio from cementation exponent for the modelling. Application of the modelling approach to a laboratory joint elastic‐electrical dataset shows that there is a systematic discrepancy in the modelled and measured joint elastic–electrical properties. It is also found that an equivalent pore aspect ratio is existing to reasonably predict the trend of the joint elastic–electrical data; however, the porosity used in the modelling is far from their measured values. Conversely, if the measured sample porosity is employed, the mentioned equivalent pore aspect ratio fails to fit either of the measured elastic and electrical rock properties. The results indicate the incapability of the cross‐property differential effective medium model for the joint elastic–electrical modelling of reservoir rocks and suggest the requirement of a new model to link the elastic and electrical properties.
Insulin peptides and their receptors regulate ovarian development and oviposition behavior in Diaphorina citri
Authors: Wang Ziye , Tan Delong , Wang Feifeng , Guo Shuhao , Liu Jinhua , Cuthbertson Andrew G. S. , Qiu Baoli , Sang Wen 
Published: June 2022

AbstractDiaphorina citri is an important vector of Citrus Huanglongbing (HLB) disease. After feeding on young host plant shoots, the population of D. citri can increase significantly. Females also only lay eggs on young shoots. However, there are few studies on the mechanism of this phenomenon. Exogenous nutrient signals can affect the insulin signaling system of D. citri after feeding on young shoots. In this study, the expression of upstream factors DcILP1, DcILP2, and DcIR in the insulin signaling system of D. citri was upregulated after feeding on young shoots. After being silenced by RNA interference technology, the results showed that the number of oviposited eggs of D. citri was significantly decreased and the ovarian development was inhibited with severe vacuolation. In addition, detection using quantitative reverse transcription–polymerase chain reaction showed that the upstream regulatory gene DcRheb of the target of rapamycin (TOR) pathway and the downstream reproduction‐related DcVg gene were also significantly downregulated. These results suggest that feeding upon young shoots may upregulate the expression levels of upstream factors DcILP1, DcILP2, and DcIR in the insulin signaling system. The signal will be through upregulating the expression of DcRheb, an upstream gene of the TOR signaling pathway. This in turn influences yolk metabolism, which eventually causes the ovaries of female D. citri to mature and therefore initiate oviposition behavior.