bluuebunny/crossref_metadata_2025_split huggingface dataset:
UJI KITOSAN SISIK IKAN HARUAN (Channa striata) TERHADAP AKTIVITAS ENZIM GLUKOSILTRANSFERASE Streptococcus mutans
Authors: Rachfa Moch. Andhika Firdausi , Tri Putri Deby Kania , Dewi Renie Kumala 
Published: November 2022

ABSTRACTBackground: Streptococcus mutans is a bacterium that acts as the main agent for dental caries. These bacteria have glucosyltransferase (GTF) enzyme which can catalyze sucrose into adhesive glucans, this pathogen nature also plays a role in biofilm structures. Haruan fish (Channa striata) of chitosan known as a natural ingredient which has antibacterial properties, the content of amine groups (NH2) in chitosan can inhibit the activity of the GTF enzyme from Streptococcus mutans Purpose: To explain the effect of chitosan from haruan fish scales on the activity of the enzyme Glucosyltransferase Streptococcus mutans. Methods: This research was a true experimental study with a post-test only design with control group design using haruan fish scales chitosan with concentration of 1.5%, 2.5%, 3.5%, 4% and measured using High Performance Liquid Chromatography HPLC to see activity of the glucosyltransferase enzyme. Results: This study showed that 1.5% concentration of haruan fish scales chitosan was able to inhibit the enzyme activity with a value of 82.689 unit. Conclusion: Haruan fish scales chitosan with concentration 1.5%, 2.5%, 3.5%, 4% has the same ability as 0.2% Chlorhexidine gluconate in inhibiting the activity of the GTF S. mutans enzyme. Key words: Chitosan, glucosyltransferase enzyme, HPLC, Streptococcus mutans. ABSTRAKLatar Belakang: Streptococcus mutans merupakan bakteri yang berperan sebagai agen utama terjadinya karies gigi. Bakteri ini memiliki enzim glukosiltransferase (GTF) yang dapat mengkatalis sukrosa menjadi glukan yang bersifat adhesive sehingga meningkatkan perlekatan bakteri, sifat patogen ini juga berperan dalam pembentukan struktur biofilm. Kitosan sisik ikan haruan (Channa striataGen gtfB, gtfC, gtfD) diketahui sebagai bahan alami yang memiliki sifat antibakteri. Kandungan gugus amina (NH2) dalam kitosan ikan haruan dapat menghambat aktivitas enzim GTF Streptococcus mutans. Tujuan: Menjelaskan pengaruh kitosan sisik ikan haruan (Channa striata) Terhadap aktivitas enzim Glukosiltransferase Streptococcus mutans. Metode: penelitian true experimental dengan rancangan post test only with control group design menggunakan kitosan sisik ikan haruan konsentrasi 1,5%, 2,5%, 3,5%, 4% dan diukur menggunakan High Performance Liquid Chromatography (HPLC) untuk melihat aktivitas enzim glukosiltransferase. Hasil: Hasil dari pengujian menunjukkan bahwa kitosan sisik ikan haruan konsentrasi 1,5% sudah mampu menghambat aktivitas enzim dengan nilai 82,689unit Kesimpulan: Kitosan sisik ikan haruan konsentrasi 1,5%, 2,5%, 3,5%, 4% memiliki kemampuan yang setara dengan Chlorhexidine gluconate 0,2% dalam menghambat aktivitas enzim GTF S. mutans. Kata kunci : Enzim Glukosiltransferase, HPLC, Kitosan, Streptococcus mutans.
PENGARUH PAPARAN RADIASI TERHADAP pH SALIVA
Authors: Aulia Nida , Sukmana Bayu Indra , Diana Sherli 
Published: November 2022

ABSTRACTBackground: The field of medicine is currently experiencing high progress, one of which is the radiography. The use of X-rays in medicine is as a diagnostic and therapeutic aid. X-rays can be used for diagnosis and treatment of patients. Therapy using radiation is called radiotherapy. Radiotherapy is one way of dealing with cancer, including cancer of the head and neck. The basic principle in radiotherapy for cancer or malignancy is to cause damage to every molecule that is exposed to radiation, resulting in the rupture of cell molecules so that cell damage occurs. Objective: To review various research articles related to the description of the effect of radiation on salivary pH. Methods: A review was conducted on 8 journals that were found to match the inclusion criteria such as journals available in full-text form and research subjects on the effect of radiation on salivary pH. Results: Based on 8 articles that have been reviewed, it was found that 8 articles (100%) stated that there was an effect of radiation on salivary pH after exposure to radiation after radiotherapy. The results showed that articles related to decreasing salivary pH stated that after being exposed to radiation after radiotherapy they tended to decrease salivary pH rather than increase it. Conclusion: there was a decrease in salivary pH after exposure to radiation. Keywords: Radiation, radiotherapy, salivary glands, salivary pH, X-rays. ABSTRAK Latar Belakang: Bidang kedokteran saat ini telah mengalami kemajuan yang tinggi, salah satunya bagian radiografi. Penggunaan sinar-X dalam bidang kedokteran adalah sebagai alat bantu diagnostik dan terapi. Sinar-X dapat dimanfaatkan untuk diagnosa maupun terapi pasien. Terapi dengan menggunakan radiasi disebut radioterapi. Radioterapi merupakan salah satu cara dalam usaha menanggulangi kanker, termasuk kanker pada bagian kepala dan leher. Prinsip dasar dalam radioterapi kanker atau keganasan adalah menimbulkan kerusakan pada setiap molekul yang terkena paparan sinar radiasinya mengakibatkan pecahnya molekul-molekul sel sehingga terjadi kerusakan sel. Tujuan: Mengulas berbagai artikel penelitian yang berkaitan dengan gambaran pengaruh radiasi terhadap pH saliva. Metode: Review dilakukan pada 8 jurnal yang ditemukan sesuai dengan kriteria inklusi seperti jurnal tersedia dalam bentuk full-text dan subjek penelitian pengaruh radiasi terhadap pH saliva. Hasil: Berdasarkan 8 artikel yang telah dilakukan telaah, didapatkan bahwa 8 artikel (100%) menyatakan bahwa terdapat pengaruh radiasi terhadap pH saliva setelah terkena paparan radiasi pasca radioterapi. Hasil penelitian didapatkan bahwa artikel yang berkaitan dengan penurunan pH saliva menyatakan setelah terkena radiasi pasca radioterapi cenderung dapat menurunkan pH saliva daripada meningkatkan pH tersebut. Kesimpulan: Terjadi penurunan pH saliva setelah terkena paparan radiasi. Kata kunci: Kelenjar saliva, , pH saliva, radiasi, radioterapi, sinar-X.
PENGARUH KOMBINASI BUDESONIDE DAN FORMOTEROL TERHADAP KEKASARAN PERMUKAAN RESIN KOMPOSIT BIOAKTIF
Authors: Rahmasari Alya , Erlita Isyana , Diana Sherli 
Published: November 2022

ABSTRACT Background: The combination of budesonide and formoterol is an effective treatment for asthma. The fumaric acid contained in the combination asthma drug budesonide and formoterol affects the condition of the oral cavity, so that it becomes acidic and causes surface roughness of tooth restorations, one of which is a composite resin whose physical properties and materials have been developed, namely bioactive composite resin. Objective: To know the effect of exposure to the combination of budesonide and formoterol asthma drug 320/9µg, 640/18µg, which was soaked only in artificial saliva on the surface roughness of the composite resin. Method: This study use a sample in the form of a disc-shaped bioactive composite resin, 10mm in diameter and 2mm in thickness using ISO 4049 specifications and divided into 3 groups, namely the group exposed to the combine asthma drug budesonide and formoterol at doses of 320/9µg, 640/18µg, and the group that was immersed in artificial saliva. Result: One Way ANOVA and Post Hoc Bonferonni showed a significant difference in the roughness value of the bioactive composite resin between group exposed to the combination of budesonide and formoterol asthma drug 640/18µg and the group that was soaked only in artificial saliva. Conclusion: There is an effect of exposure to the combination of budesonide and formoterol asthma drug on the surface roughness of the bioactive composite resin. Keywords: bioactive composite resin, budesonide and formoterol, surface roughness. ABSTRAK Latar Belakang: Kombinasi budesonide dan formoterol merupakan penanganan yang efektif untuk mengatasi asma. Asam fumarat yang terkandung dalam obat asma kombinasi budesonide dan formoterol mempengaruhi kondisi rongga mulut, sehingga menjadi asam dan menyebabkan kekasaran permukaan restorasi gigi yang salah satunya adalah resin komposit yang telah dikembangkan sifat fisik dan materialnya yaitu resin komposit bioaktif. Tujuan: Untuk mengetahui pengaruh paparan obat asma kombinasi budesonide dan formoterol 320/9µg, 640/18µg, dan hanya direndam saliva buatan terhadap kekasaran permukaan resin komposit. Metode: Penelitian ini menggunakan sampel berupa resin komposit bioaktif yang berbentuk cakram berdiameter 10mm dan tebal 2mm menggunakan spesifikasi ISO 4049 serta dibagi menjadi 3 kelompok yaitu kelompok paparan obat asma kombinasi budesonide dan formoterol 320/9µg, 640/18µg dan yang hanya direndam saliva buatan. Hasil: One Way ANOVA dan Post Hoc Bonferonni menunjukkan perbedaan bermakna pada nilai kekasaran resin komposit bioaktif antara kelompok paparan obat asma kombinasi budesonide dan formoterol 640/18µg dengan kelompok yang hanya direndam saliva buatan. Kesimpulan: Terdapat pengaruh paparan obat asma kombinasi budesonide dan formoterol terhadap kekasaran permukaan resin komposit bioaktif. Kata kunci: Budesonide dan formoterol,kekasaran permukaan, resin komposit bioaktif.
PENGARUH EKSTRAK KULIT BATANG MANGGA KASTURI (Mangifera casturi) TERHADAP KEPADATAN HARD CALLUS
Authors: Manto Taqwa Handraji , Sukmana Bayu Indra , Ichrom Nahzi Muhammad Yanuar 
Published: November 2022

ABSTRACTBackground: Dental and oral health is a unity of body health, so their health must be maintained. One of the most common dental and oral diseases suffered by Indonesians is dental caries. This dental and oral health problem resulted in tooth extraction due to caries, so it requires medication to accelerate wound healing after tooth extraction. Some parts of the kasturi mango plant, such as leaves, fruits, and bark are known to have active substances and potentially against the density of hard callus. Purpose: to review various research articles related to the overview of the effect of mango kasturi bark extract (Mangifera casturi) on hard callus density. Method: All reviewed articles are obtained from Google Scholar and Science Direct data sources searches, and has a maximum journal publishing time span of the last 10 years. Result: The review was conducted in 10 journals found to fit inclusion criteria such as journals available in full-text form and research subjects extracting mango kasturi bark (Mangifera casturi). Conclusion: Kasturi mango bark extract has a direct and indirect influence on hard callus density. Keywords :, hard callus, mango kasturi bark extract, wound healing ABSTRAK Latar Belakang: Kesehatan gigi dan mulut merupakan satu kesatuan dari kesehatan tubuh yang harus dipelihara kesehatannya, salah satu penyakit gigi dan mulut yang paling banyak diderita masyarakat Indonesia ialah karies gigi. Permasalahan kesehatan gigi dan mulut ini mengakibatkan pencabutan gigi karena karies, sehingga memerlukan obat untuk mempercepat penyembuhan luka pasca ekstraksi gigi. Beberapa bagian tanaman mangga kasturi, seperti daun, buah, dan kulit batangnya diketahui memiliki zat aktif dan berpotensi terhadap kepadatan hard callus. Tujuan: mengulas berbagai artikel penelitian yang berkaitan dengan gambaran pengaruh ekstrak kulit batang mangga kasturi (Mangifera casturi) terhadap kepadatan hard callus. Metode: Semua artikel yang direview diperoleh dari pencarian sumber data Google Scholar, dan Science Direct yang memiliki rentang waktu penerbitan jurnal maksimal 10 tahun terakhir. Hasil: Review dilakukan pada 10 jurnal yang ditemukan sesuai dengan kriteria inklusi seperti jurnal tersedia dalam bentuk full-text dan subjek penelitian ekstrak kulit batang mangga kasturi (Mangifera casturi). Kesimpulan: Ekstrak kulit batang mangga kasturi memiliki pengaruh secara langsung dan tidak langsung terhadap kepadatan hard callus. Kata kunci: Penyembuhan luka, ekstrak kulit batang mangga kasturi, hard callus
UJI TOKSISITAS EKSTRAK KULIT BATANG ULIN (Eusideroxylon zwageri) TERHADAP SEL FIBROBLAS BHK-21 SECARA IN VITRO
Authors: Salwa Ismi Natasya , Firdaus I Wayan Arya Krishnawan , Azizah Aulia 
Published: November 2022

ABSTRACTBackground: Antioxidants can come from plants that contain flavonoids such as ironwood. The bark of ironwood is declared effective to be used as a mouthwash because of the content of flavonoids, phenolics, tannins, saponins, alkaloids, and terpenoids. Ironwood bark extract to be used as an alternative material must be safe for oral tissues, so it is necessary to do a toxicity test. Objective: To analyze the toxic effect of ironwood bark extract through IC50 on BHK-21 fibroblast cells. Methods: This study was a pure laboratory experimental study with posttest-only control group design, consisting of 12 groups with 10 treatment groups given ironwood bark extract at concentrations of 5%, 15%, 25%, 35%, 45%, 55%. , 65%, 75%, 85%, and 95% and 2 control groups, namely cell control and media control. It was repeated 3 times so that the total sample was 36 samples. Toxicity test media used MTT assay which produced color absorbance and cell viability was calculated. Results: The results showed that the cell viability of the entire treatment group was >60% so it had no toxic effect. In addition, based on the IC50> 0.1%, which is 3.746%, it has no toxic effect on BHK-21 fibroblast cells. Conclusion: Ironwood bark extract at concentrations of 5%, 15%, 25%, 35%, 45%, 55%, 65%, 75%, 85%, and 95% had no toxic effect on BHK-21 fibroblast cells. Keywords: BHK-21 fibroblast cells, Ironwood bark extract, , toxicity ABSTRAKLatar Belakang: Antioksidan dapat berasal dari tanaman yang mengandung flavonoid seperti ulin. Kulit batang ulin dinyatakan efektif untuk dijadikan obat kumur karena adanya kandungan flavonoid, fenolik, tanin, saponin, alkaloid, dan terpenoid. Ekstrak kulit batang ulin untuk dijadikan sebagai bahan alternatif harus bersifat aman untuk jaringan rongga mulut sehingga perlu dilakukan uji toksisitas. Tujuan: Menganalisis efek toksik ekstrak kulit batang ulin melalui IC50 terhadap sel fibroblas BHK-21. Metode: Penelitian eksperimental laboratoris murni dengan posttest-only with control group design, terdiri dari 12 kelompok dengan 10 kelompok perlakuan yang diberi ekstrak kulit batang ulin konsentrasi 5%, 15%, 25%, 35%, 45%, 55%, 65%, 75%, 85%, dan 95% dan 2 kelompok kontrol, yaitu kontrol sel dan kontrol media. Dilakukan 3 kali pengulangan sehingga total sampel berjumlah 36 sampel. Media uji toksisitas menggunakan MTT assay yang menghasilkan absorbansi warna dan dilakukan perhitungan viabilitas sel. Hasil: Viabilitas sel seluruh kelompok perlakuan adalah >60% sehingga tidak memiliki efek toksik. Selain itu, berdasarkan nilai IC50>0,1% yaitu sebesar 3,746% tidak memiliki efek toksik terhadap sel fibroblas BHK-21. Kesimpulan: Ekstrak kulit batang ulin pada konsentrasi 5%, 15%, 25%, 35%, 45%, 55%, 65%, 75%, 85%, dan 95% tidak memiliki efek toksik terhadap sel fibroblas BHK-21. Kata kunci: Esktrak kulit batang ulin, sel fibroblas BHK-21, toksisitas.
HUBUNGAN ANTARA PENGETAHUAN KESEHATAN GIGI DENGAN NILAI INDEKS DMF-T SISWA SEKOLAH MENENGAH PERTAMA
Authors: Ryzanur.A M. Fahrul , Widodo Widodo , Adhani Rosihan 
Published: November 2022

ABSTRACTBackground: The prevalence of people with oral and dental problems in Indonesia according to Riskesdas in 2018 was 57.6% with the National DMF-T index of 7.1. Lack of knowledge about oral and dental health causes a person not knowing the causes and prevention of dental caries. Purpose: To determine the results of published studies related to the relationship between dental health knowledge and the DMF-T index value of junior high school students. Method: A literature review with the type of narrative literature review. Data collection is carried out through electronic media. The data source is Secondary data from journals regarding the relationship between dental and oral health knowledge on the DMF-T score of junior high school students. Results: The results of the review of 12 journals conducted, found that the largest average percentage of DMF-T from 6 journals was in the low category, which was 27.45%, the average percentage of the largest dental and oral health knowledge level of the 5 journals was in the good / high, which is equal to 57.68%. Conclusion: There is a relationship between the level of knowledge and the DMF-T index, most of the DMF-T index tends to be low in students with high levels of knowledge. Keywords: DMF-T index, Junior high school students, Level of knowledge. ABSTRAKLatar Belakang: Prevalensi masyarakat yang bermasalah gigi dan mulut di Indonesia menurut Riskesdas tahun 2018 sebesar 57,6% dengan indeks DMF-T Nasional sebesar 7,1%. Pengetahuan yang kurang mengenai kesehatan gigi dan mulut menyebabkan seseorang tidak mengetahui penyebab dan pencegahan karies gigi. Tujuan: Untuk mengetahui hasil penelitian yang sudah dipublikasikan yang berkaitan dengan hubungan pengetahuan kesehatan gigi dengan nilai indeks DMF-T siswa SMP. Metode: Literature review menggunakan jenis narrative literature review. Pengumpulan data dilakukan melalui media elektronik. Sumber data berupa data sekunder dari jurnal mengenai hubungan pengetahuan kesehatan gigi dan mulut terhadap nilai DMF-T siswa SMP. Hasil: Hasil review 12 jurnal yang dilakukan, ditemukan rata-rata persentase DMF-T terbesar dari 6 jurnal pada kategori rendah, yaitu sebesar 27,45%, rata-rata persentase tingkat pengetahuan kesehatan gigi dan mulut terbesar dari 5 jurnal tersebut adalah pada kategori baik/tinggi, yaitu sebesar 57,68%. Kesimpulan: Terdapat hubungan tingkat pengetahuan dengan indeks DMF-T, sebagian besar indeks DMF-T cenderung rendah pada siswa dengan tingkat pengetahuan tinggi. Kata kunci: Indeks DMF-T, Siswa SMP, Tingkat pengetahuan.
PENGARUH EKSTRAK DAUN KASTURI TERHADAP KADAR LIMFOSIT MENCIT JANTAN (Mus musculus) YANG DIPAPAR SINAR-X RADIOGRAFI PERIAPIKAL
Authors: Ennisa Syifa , Aspriyanto Didit , Taufiqurrahman Irham 
Published: November 2022

ABSTRACTBackground: Periapical radiographic X-ray exposure can cause blood cell damage, such as lymphocyte damage. Direct damage occurs when it attacks the DNA and RNA of cells. Indirect damage occurs through the formation of free radicals. One of the natural antioxidants that can be used is kasturi leaves. Kasturi leaf extract contains active ingredients such as flavonoids, phenols, alkaloids, terpenoids, and saponins that can inhibit free radical activity. Objective: To measure and analyze the effect of kasturi leaf extract on the increase in lymphocytes levels of male mice exposed to x-ray periapical radiographs. Methods: This study used a true experimental method with a post test only design with a control group design. The samples used were 20 male mice aged 3-4 months with 20-25 grams bodyweight. Mice were divided into 5 groups, each group consisted of 4 mice. Mice were given kasturi leaf extract and exposed to x-ray periapical radiographs. Mice lymphocytes levels were measured automatically using a hematology analyzer. Results: Lymphocyte levels in P1 group = 3,400 x 103/µL, P2 group = 5,725 x 103/µL, P3 group = 7,825 x 103/µL, P4 group = 9,750 x 103/µL, and P5 group = 5,375 x 103/µL. Conclusion: Differences in lymphocyte levels were influenced by antioxidants from kasturi leaf extract and large differences in the radiation dose received. Keywords : Kasturi leaf extract, Lymphocytes, Periapical radiography ABSTRAKLatar Belakang: Paparan sinar-X radiografi periapikal dapat menyebabkan kerusakan sel darah, seperti kerusakan limfosit. Kerusakan langsung terjadi apabila mengenai DNA dan RNA sel. Kerusakan tidak langsung terjadi melalui pembentukan radikal bebas. Salah satu antioksidan alami yang dapat digunakan adalah daun kasturi. Ekstrak daun kasturi mengandung bahan aktif seperti flavonoid, fenol, alkaloid, terpenoid, dan saponin yang dapat menghambat aktivitas radikal bebas. Tujuan: Untuk mengukur dan menganalisis pengaruh ekstrak daun kasturi terhadap peningkatan kadar limfosit mencit jantan yang dipapar sinar-X radiografi periapikal. Metode: True experimental dengan post test only with control group design. Sampel yang digunakan adalah 20 ekor mencit jantan berusia 3-4 bulan dengan berat badan 20-25 gram. Mencit dibagi menjadi 5 kelompok, masing-masing kelompok berjumlah 4 ekor mencit. Mencit diberi ekstrak daun kasturi dan dipapar sinar-X radiografi periapikal. Kadar limfosit mencit diukur secara automatis menggunakan hematology analyzer. Hasil: Kadar limfosit kelompok P1 = 3,400 x 103/µL, kelompok P2 = 5,725 x 103/µL, kelompok P3 = 7,825 x 103/µL, kelompok P4 = 9,750 x 103/µL, dan kelompok P5 = 5,375 x 103/µL. Kesimpulan: Perbedaan kadar limfosit terjadi karena pengaruh antioksidan ekstrak daun kasturi dan perbedaan besar dosis radiasi yang diterima. Kata kunci: Ekstrak daun kasturi, Limfosit, Radiografi periapikal
PENGARUH JARAK PENYINARAN TERHADAP NILAI DERAJAT KONVERSI RESIN KOMPOSIT BIOAKTIF
Authors: Wita Bancin Ulfa Asma , Erlita Isyana , Diana Sherli 
Published: November 2022

ABSTRACTBackground: The improper irradiation process causes imperfect polymerization, so that the hardness of the composite resin, material strength, and color stability of the resulting composite resin are not optimal and water absorption increases. The long irradiation distance will result in the intensity of the light obtained getting smaller because the light can not reach the composite resin optimally and the degree of perfection of the polymerization of the composite resin will decrease. Objectives: The purpose of this study was to determine the difference between the irradiation distance and the degree of conversion of the bioactive composite resin and to analyze the ratio of the irradiation distance of 0 mm, 1 mm, and 5 mm to the value of the degree of conversion of the bioactive composite resin. Methods: This research uses a true experimental method with a post-test only design with a control group design with a simple random sampling technique. Results: The results showed that the highest degree of conversion of bioactive composite resins was at a 0 mm irradiation distance of 38.57%, 1 mm irradiation of 36.02% and the lowest was at a 5 mm irradiation distance of 31.90%. Conclusion: The highest degree of conversion of bioactive composite resin is at a 0 mm irradiation distance. Keywords: Beam distance, Composite resin, Degree of conversion, Light intensityABSTRAKLatar belakang: Proses penyinaran yang kurang tepat menyebabkan polimerisasi tidak sempurna, sehingga kekerasan dari resin komposit, kekuatan bahan, stabilitas warna dari resin komposit yang dihasilkan tidak maksimal serta penyerapan air meningkat. Jarak penyinaran yang jauh akan mengakibatkan intensitas sinar yang didapat semakin kecil karena sinar tidak dapat mencapai resin komposit secara optimal dan derajat kesempurnaan polimerisasi resin komposit akan berkurang. Tujuan: Tujuan penelitian adalah untuk mengetahui perbedaan jarak penyinaran terhadap nilai derajat konversi resin komposit bioaktif serta menganalisis perbandingan jarak penyinaran 0 mm, 1 mm, dan 5 mm terhadap nilai derajat konversi resin komposit bioaktif. Metode: penelitan ini menggunakan metode eksperimental murni (true experimental) dengan rancangan post-test only with control group design dengan teknik pengambilan sampel simple random sampling. Hasil: Hasil penelitian menunjukkan nilai derajat konversi resin komposit bioaktif tertinggi berada pada jarak penyinaran 0 mm sebesar 38.57%, penyinaran 1 mm sebesar 36.02% dan terendah berada pada jarak penyinaran 5 mm sebesar 31.90%. Kesimpulan: Nilai derajat konversi resin komposit bioaktif tertinggi berada pada jarak penyinaran 0 mm. Kata Kunci: Derajat konversi, Intensitas sinar, Jarak sinar, Resin komposit