bluuebunny/crossref_metadata_2025_split huggingface dataset:
Power, Politics and Children’s Citizenship: The Silencing of Civil Society
Authors: Osler Audrey , Kato Aya 
Published: June 2022

Abstract
Children remain marginalised in theoretical analyses of citizenship and political rights, with their partial citizenship status attracting minimal attention. We consider the ontological need for political engagement, children’s political agency and intergenerational justice. We discuss how Derrida’s hospitality concept may inform analyses of power structures that serve to exclude children from the demos. We then examine the case of Japan where education law neglects children’s political rights, though respect for human rights and popular sovereignty are core constitutional values. Analysis of parliamentary debates addressing Article 12 and children’s right to be heard and organise collectively reveals a long-standing ideological divide concerning children’s political participation. The Committee on the Rights of the Child has explained Japan’s reluctance to implement Article 12 as reflecting “traditional” attitudes. The reality is more complex. From the late 1950s, Japan experienced a wave of student-led protests, focusing on the US-Japan Anpo Security Treaty. Subsequently, the Japanese government prioritised public order over students’ political rights, and global economic competitiveness over citizenship rights. Article 12 remains a site of struggle between those wishing to extend children’s citizenship rights and those who wish to maintain their partial citizenship, fearing social unrest and a focus away from global economic competitiveness.
Who, or What, is Lost: Singapore’s Impressions of Christmas Island, c. 1960–1990
Authors: Chan Ying-kit 
Published: June 2022

Abstract
Although Singapore no longer governs Christmas Island, either on behalf of its British colonial administrators or for itself, some Singaporeans continue to regard it as a lost territory and have false impressions that it once belonged and should again belong to Singapore. By examining this complexity related to Christmas Island and its possible implications for Singapore’s national psyche, this paper surveys the newspapers of Singapore and oral history records of Singaporean ministers and officials for accounts of Christmas Island. It suggests that Singaporean newspapers’ portrayal of Christmas Island as a neglected Australian overseas territory contributed to some Singaporeans’ perception that Christmas Island might actually be better off with Singapore; others even had a misconception of Christmas Island as a lost territory. Such opinions have never really dissipated because the government has never publicly clarified the transfer of Christmas Island and rejected claims about its “sale” to Australia.
Near-Inertial Wave Interactions and Turbulence Production in a Kuroshio Anticyclonic Eddy
Authors: Essink Sebastian , Kunze Eric , Lien Ren-Chieh , Inoue Ryuichiro , Ito Shin-ichi 
Published: June 2022

Abstract
Interactions between near-inertial waves and the balanced eddy field modulate the intensity and location of turbulent dissipation and mixing. Two EM-APEX profiling floats measured near-inertial waves generated by Typhoons Mindulle, 22 August 2016, and Lionrock, 30 August 2016, near the radius of maximum velocity of a mesoscale anticyclonic eddy in the Kuroshio–Oyashio confluence east of Japan. High-vertical-wavenumber near-inertial waves exhibit energy fluxes inward toward eddy center, consistent with wave refraction/reflection at the eddy perimeter. Near-inertial kinetic energy tendencies are nearly two orders of magnitude greater than observed turbulent dissipation rates ε, indicating propagation/advection of wave packets in and out of the measurement windows. Between 50 and 150 m, ε ∼ (10−10) W kg−1, more than an order of magnitude weaker than outside the eddy, pointing to near-inertial wave breaking at different depths or eddy radii. Between 150 and 300 m, small-scale inertial-period patches of intense turbulence with near-critical Ri occur where comparable near-inertial and eddy shears are superposed. Three-dimensional ray-tracing simulations show that wave dynamics at the eddy perimeter are controlled by radial gradients in vorticity and Doppler shifting with much weaker contributions from vertical gradients, stratification, and sloping isopycnals. Surface-forced waves are initially refracted downward and inward, consistent with the observed energy flux. A turning-point shadow zone is found in the upper pycnocline, consistent with weak observed dissipation rates. In summary, the geometry of wave–mean flow interaction creates a shadow zone of weaker near-inertial waves and turbulence in the upper part while turning-point reflections amplify wave shear leading to enhanced dissipation rates in the lower part of the eddy.
The University of Alabama at Birmingham Surgery Community Network: Tackling the Challenges of Rural Surgery
Authors: Kraus Abigayle C. , Gunnells Drew J. , Chu Daniel I. , Kennedy Alexis E. , Hughes Tyler G. , Chen Herb , Hollis Robert H. , Porterfield John R. , Stahl Richard D. , Kennedy Gregory D. 
Published: June 2022

Over the past 5 years, The University of Alabama at Birmingham (UAB) Department of Surgery has taken a keen interest in the practice of surgery in rural Alabama and has established the UAB surgery community network. Our goal is to improve the delivery of surgical care in rural areas through active recruitment of rural surgeons, the development of research around rural surgery practice, and the expansion of a surgery network throughout the state. Here, we will present the challenges faced by rural surgery, our early work to address these challenges, and offer a plan for moving forward.
Adherence Patterns and Acceptability of a Perioperative, App-Based Mindfulness Meditation Among Surgical Patients With Chronic Pain
Authors: Diller Maggie L. , Mascaro Jennifer , Haack Carla , Master Viraj 
Published: June 2022

Identifying barriers to compliance with mindfulness-based interventions (MBIs) during the perioperative period is paramount to the design and implementation of non-pharmacologic, opiate-sparing pain regimens. We prospectively investigated the acceptability and adherence patterns of an app-based MBI amongst surgical patients with chronic pain. Patients were provided a subscription code to a meditation app and encouraged to use the app an average of 10 minutes/day over a 6-week study period. Patients reported a high level of interest in using the app prior to enrollment. 71% used the app at least once, 30% for half the recommended time, and 8% for the recommended amount of time. 88% of respondents enjoyed using the app and agreed it improved mental health and stress levels. Surgical patients with pre-existing pain report a high level of interest in utilizing MBIs perioperatively. Identifying barriers to compliance represents an important area of future investigation.
Does Physical Activity Improve Inhibition in Kindergarteners? A Pilot Study
Authors: Giordano Giulia , Alesi Marianna 
Published: June 2022

Substantial empirical evidence supports the positive effects of physical activity (PA) on executive functions, but not all forms of physical activity benefit equally. Among kindergarteners, cognitively-engaging exercise seems to more strongly effect EF than simple exercise. We aimed to investigate several qualitatively different exercise formats on kindergarteners' inhibition. Participants were 75 children (M age = 68.1 months), recruited from 14 classrooms of three kindergarten schools. They were randomly assigned to three groups: control group, free play group (non-cognitively-engaging PA), and an intervention group (cognitively-engaging PA). The intervention group performed 18 sessions of a cognitively engaging PA (tasks requiring movements and inhibitory behavior skills). We assessed “hot” and “cool” aspects of inhibition using the Day-Night Stroop test, Head-Shoulders-Knees-Toes, Gift Wrap, and Snack Delay. We found that the intervention group obtained a more consistent performance improvement on post-test measures of hot and cool inhibition than did the free play group.
Financial Inclusion Through Banking for the Poor: A Study on Cycle Rickshaw Pullers in West Bengal
Authors: Maity Sudarshan , Sahu Tarak Nath , Biswas Debasish 
Published: June 2022

Financial services actively contribute to the economic development of society. This leads to social safety that protects people from economic shocks. The present study seeks to ascertain whether cycle rickshaw pullers of West Bengal have bank accounts and to also investigate if bank account awareness among cycle rickshaw pullers are affected by different socio-economic factors. The study has been conducted on 170 rickshaw pullers who belong to the poor and marginalized sections of society. The study uses logistic regression to estimate important factors that influence the opening of a bank account. The goodness of fit of the model is checked in terms of the Hosmer–Lemeshow test. A large percentage of this group of rickshaw pullers is excluded from banking services. Among the 10 explanatory variables, the study finds that the number of years pulling cycle rickshaws, the monthly income and social participation are the factors that significantly influence the opening of a bank account. It has been observed that the respondents have meager incomes, low levels of health care and personal well-being, lives entrapped in poverty and are, on the whole, excluded from the mainstream. To include them in the mainstream financial services, the study suggests valid recommendations to draw the attention of the regulators and banks towards financial inclusion. JEL Codes: G21, G29
Assessing the Impact of Community Factors on Acute Care Nurses’ Job Satisfaction and Turnover Intention
Authors: Yasin Yasin M. , Kerr Michael S. , Wong Carol A. , Bélanger Charles H. 
Published: June 2022

BackgroundCommunity factors may affect nurses’ job behavior and decision making. There is a gap in the literature regarding the impact of community satisfaction, family ties, and community preferences on acute care nurses’ turnover intention and job satisfaction. Furthermore, no studies have examined the differences in community satisfaction, community preferences, and family ties among nurses working in rural and urban settings.PurposeTo identify the impact of family ties, community satisfaction, and community preferences on turnover intention and job satisfaction among acute care nurses working in Ontario's urban and rural areas.MethodsDescriptive correlational survey design was used in this study. A targeted stratified sampling technique was used to recruit acute care nurses working in Ontario's urban and rural areas (N = 349) between May 2019 and July 2019. Dillman's approach was used to guide data collection. Parametric and non-parametric tests were used for data analysis.ResultsA significant association was found between working settings and community preferences. A statistically significant positive relationship between community satisfaction and nurses’ job satisfaction was identified. Furthermore, community satisfaction had a negative impact on turnover intention. Neither community preference nor family ties were significantly associated with turnover intention or job satisfaction.ConclusionThe study suggests that community satisfaction can influence important nurse work-related outcomes. Future studies should replicate and validate these results in different contexts and cultures. Retaining nurses may be difficult if they are not satisfied with their communities.
CSF TNF and osteopontin levels correlate with the response to dimethyl fumarate in early multiple sclerosis
Authors: Marastoni Damiano , Pisani Anna I. , Schiavi Gianmarco , Mazziotti Valentina , Castellaro Marco , Tamanti Agnese , Bosello Francesca , Crescenzo Francesco , Ricciardi Giuseppe K. , Montemezzi Stefania , Pizzini Francesca B. , Calabrese Massimiliano 
Published: June 2022

Background: Disease activity in the first years after a diagnosis of relapsing-remitting multiple sclerosis (RRMS) is a negative prognostic factor for long-term disability. Markers of both clinical and radiological responses to disease-modifying therapies (DMTs) are advocated. Objective: The objective of this study is to estimate the value of cerebrospinal fluid (CSF) inflammatory markers at the time of diagnosis in predicting the disease activity in treatment-naïve multiple sclerosis (MS) patients exposed to dimethyl fumarate (DMF). Methods: In total, 48 RRMS patients (31 females/17 males) treated with DMF after the diagnosis were included in this 2-year longitudinal study. All patients underwent a CSF examination, regular clinical and 3T magnetic resonance imaging (MRI) scans that included the assessment of white matter (WM) lesions, cortical lesions (CLs) and global cortical thickness. CSF levels of 10 pro-inflammatory markers – CXCL13 [chemokine (C-X-C motif) ligand 13 or B lymphocyte chemoattractant], CXCL12 (stromal cell-derived factor or C-X-C motif chemokine 12), tumour necrosis factor (TNF), APRIL (a proliferation-inducing ligand, or tumour necrosis factor ligand superfamily member 13), LIGHT (tumour necrosis factor ligand superfamily member 14 or tumour necrosis factor superfamily member 14), interferon (IFN) gamma, interleukin 12 (IL-12), osteopontin, sCD163 [soluble-CD163 (cluster of differentiation 163)] and Chitinase3-like1 – were assessed using immune-assay multiplex techniques. The combined three-domain status of ‘no evidence of disease activity’ (NEDA-3) was defined by no relapses, no disability worsening and no MRI activity, including CLs. Results: Twenty patients (42%) reached the NEDA-3 status; patients with disease activity showed higher CSF TNF ( p = 0.009), osteopontin ( p = 0.005), CXCL12 ( p = 0.037), CXCL13 ( p = 0.040) and IFN gamma levels ( p = 0.019) compared with NEDA-3 patients. After applying a random forest approach, TNF and osteopontin revealed the most important variables associated with the NEDA-3 status. Six molecules that emerged at the random forest approach were added in a multivariate regression model with demographic, clinical and MRI measures of WM and grey matter damage as independent variables. TNF levels confirmed to be associated with the absence of disease activity: odds ratio (OR) = 0.25, CI% = 0.04–0.77. Conclusion: CSF inflammatory markers may provide prognostic information in predicting disease activity in the first years after DMF initiation. CSF TNF levels are a possible candidate in predicting treatment response, in addition to clinical, demographic and MRI variables.
Fluoroscopic and Endoscopic Calcaneal Spur Resection Without Plantar Fascial Release for Recalcitrant Plantar Fasciitis
Authors: Nakajima Kenichiro 
Published: June 2022

Background: Studies on endoscopic calcaneal spur resection (CSR) without plantar fascial release (PFR) are limited. This study aimed to review the data of patients who underwent fluoroscopic and endoscopic CSR without PFR for plantar fasciitis with a calcaneal spur to assess the effectiveness of CSR. Methods: Medical records of consecutive patients with plantar fasciitis with ≥2 mm calcaneal spur who underwent endoscopic CSR without PFR from November 2017 to December 2019 were reviewed. Patients with ≥2 years of follow-up were included, whereas those who underwent another surgery on the operated foot were excluded. Age, body mass index (BMI), follow-up duration, calcaneal spur length, duration to full weightbearing postoperatively, Japanese Society for Surgery of the Foot (JSSF) score, visual analog scale (VAS) score for pain, and complications were assessed. Results: The mean follow-up duration was 2.7 years. A total of 47 patients (31 female, 16 male; mean age, 56.4 years; mean BMI, 25.5) were included. The mean calcaneal spur length was 5.7 mm. The VAS score improved from 79.6 ± 12.9 mm preoperatively to 5.3 ± 7.3 mm postoperatively. The JSSF score improved from 54.0 ± 19.1 points preoperatively to 97.5 ± 5.7 points postoperatively (Wilcoxon signed-rank test, P < .001, respectively). The mean duration to full weightbearing postoperatively was 4.4 ± 4.2 days. Two patients presented with tenderness, and one presented with hypesthesia at the portal site. Conclusion: Endoscopic CSR without PFR resulted in good outcomes, early return to full weightbearing, and few complications in patients with plantar fasciitis with ≥2 mm calcaneal spur. The results suggested that CSR was sufficient to relieve symtoms and improve function. PFR may not be necessary for treating plantar fasciitis with calcaneal spur. Level of Evidence: Level IV, retrospective case series.
Effects of habitat gradient and agro-climatic variation on selected soil physical and chemical properties in the Bale Mountains national park, south-eastern Ethiopia
Authors: Ahmedin Annissa Muhammed , Elias Eyasu 
Published: June 2022

Abstract
Background
Increasing evidence suggests that anthropogenic effects are responsible for drastic changes in landscape patterns and ecosystem services. This study aims to assess the effects of landscape change and agro-climatic variation on selected soil physical and chemical properties in the Bale Mountains national park. A combination of stratified and systematic sampling techniques was employed to draw representative soil samples. A total of 72 soil samples (3 agro-climatic zones × 3 land cover types × 2 habitat gradients × 4 replications = 72) at a depth of 0–20 cm were collected for the soil physical and chemical property analysis. A two-way analysis of variance was conducted to determine the level of variation in soil parameters. Tukey’s honest significance difference (HSD) test was used to compare treatment means at a 0.05 level of significance.

Results
The results suggest that soil parameters differed significantly (p < 0.05) among agro-climatic zones, land cover, and habitat gradients. The soil pH, SOC, TN, AP, CEC and clay content were significantly higher in the lower altitude, natural vegetation and interior habitat, whereas the soil sand and silt content as well as the soil bulk density were significantly higher in the farmland and edge habitat.

Conclusions
Conservation and restoration priority should be given to those vegetation types and ecosystems that are highly affected by human interferences such as the grassland in the middle altitude, ericaceous land in the higher altitude, and moist forest in the lower altitudes.
Comparative genomic analysis reveals contraction of gene families with putative roles in pathogenesis in the fungal boxwood pathogens Calonectria henricotiae and C. pseudonaviculata
Authors: Rogers Layne W. , Koehler Alyssa M. , Crouch Jo Anne , Cubeta Marc A. , LeBlanc Nicholas R. 
Published: June 2022

AbstractBackgroundBoxwood blight disease caused byCalonectria henricotiaeandC. pseudonaviculatais of ecological and economic significance in cultivated and native ecosystems worldwide. Prior research has focused on understanding the population genetic and genomic diversity ofC. henricotiaeandC. pseudonaviculata, but gene family evolution in the context of host adaptation, plant pathogenesis, and trophic lifestyle is poorly understood. This study applied bioinformatic and phylogenetic methods to examine gene family evolution inC. henricotiae,C. pseudonaviculataand 22 related fungi in the Nectriaceae that vary in pathogenic and saprobic (apathogenic) lifestyles.ResultsA total of 19,750 gene families were identified in the 24 genomes, of which 422 were rapidly evolving. Among the sixCalonectriaspecies,C. henricotiaeandC. pseudonaviculatawere the only species to experience high levels of rapid contraction of pathogenesis-related gene families (89% and 78%, respectively). In contrast, saprobic speciesCalonectria multiphialidicaandC. naviculata, two of the closest known relatives ofC. henricotiaeandC. pseudonaviculata, showed rapid expansion of pathogenesis-related gene families.ConclusionsOur results provide novel insight into gene family evolution withinC. henricotiaeandC. pseudonaviculataand suggest gene family contraction may have contributed to limited host-range expansion of these pathogens within the plant family Buxaceae.
Mitochondrial DNA sequences and transcriptomic profiles for elucidating the genetic underpinnings of cisplatin responsiveness in oral squamous cell carcinoma
Authors: Aminuddin Amnani , Ng Pei Yuen , Chua Eng Wee 
Published: June 2022

Abstract
Objectives
Functional genetic variation plays an important role in predicting patients’ response to chemotherapeutic agents. A growing catalogue of mitochondrial DNA (mtDNA) alterations in various cancers point to their important roles in altering the drug responsiveness and survival of cancer cells. In this work, we report the mtDNA sequences, obtained using a nanopore sequencer that can directly sequence unamplified DNA, and the transcriptomes of oral squamous cell carcinoma (OSCC) cell lines with differing responses to cisplatin, to explore the interplay between mtDNA alterations, epigenetic regulation of gene expression, and cisplatin response in OSCC.

Data description
Two human OSCC cell lines, namely H103 and SAS, and drug-resistant stem-like cells derived from SAS were used in this work. To validate our hypothesis that cisplatin sensitivity is linked to mtDNA changes, we sequenced their mtDNA using a nanopore sequencer, MinION. We also obtained the whole transcriptomic profiles of the cells from a microarray analysis. The mtDNA mutational and whole transcriptomic profiles that we provide can be used alongside other similar datasets to facilitate the identification of new markers of cisplatin sensitivity, and therefore the development of effective therapies for OSCC.
Virtual Reality for Pain Relief in the Emergency Room (VIPER) – a prospective, interventional feasibility study
Authors: Birrenbach T. , Bühlmann F. , Exadaktylos A. K. , Hautz W. E. , Müller M. , Sauter T. C. 
Published: June 2022

AbstractBackgroundPain is one of the most common, yet challenging problems leading to emergency department (ED) presentation, despite the availability of a wide range of pharmacological therapies. Virtual reality (VR) simulations are well studied in a wide variety of clinical settings, including acute and chronic pain management, as well as anxiety disorders. However, studies in the busy environment of an adult ED are scarce.The aim of this study is to explore the feasibility and effectiveness of a VR simulation for pain and anxiety control in a convenience sample of adult ED patients presenting with traumatic and non-traumatic pain triaged 2–5 (i.e., urgent to non-urgent) with a pain rating of ≥ 3 on a numeric rating scale (NRS 0–10).MethodsProspective within-subject, repeated measures interventional feasibility pilot study at a Swiss University ED. The intervention consisted of a virtual reality simulation in addition to usual care. Pain and anxiety levels were measured using a verbally administered numeric rating scale (NRS) before and after the intervention. Information on patient experience was collected using established rating scales.ResultsFifty-two patients were enrolled. The most common pain localisations were extremities (n = 15, 28.8%) and abdomen (n = 12, 23.1%). About one third of patients presented with trauma-associated pain (n = 16, 30.8%). Duration of pain was mainly acute (< 24 h) (n = 16, 30.8%) or subacute (> 24 h) (n = 32, 61.5%). The majority of patients were triage category 3, i.e. semi-urgent (n = 48, 92.3%). Significant reduction in pain (NRS median pre-VR simulation 4.5 (IQR 3–7) vs. median post-VR simulation 3 (IQR 2–5),p < 0.001), and anxiety levels (NRS median pre-VR simulation 4 (IQR 2–5) vs. median post-VR simulation 2 (IQR 0–3),p < 0.001) was achieved, yielding moderate to large effect sizes (Cohen’s d estimate for pain reduction = 0.59 (95% CI 0.19—0.98), for anxiety level on NRS = 0.75 (95% CI 0.34—1.15). With medium immersion and good tolerability of the VR simulation, user satisfaction was high.ConclusionsVirtual reality analgesia for pain and anxiety reduction in the busy setting of an ED is feasible, effective, with high user satisfaction. Further randomized controlled studies are needed to better characterize its impact on pain perception and resource utilization.