bluuebunny/crossref_metadata_2025_split huggingface dataset:
Catalogue of solar-like oscillators observed by TESS in 120-s and 20-s cadence
Authors: Hatt Emily , Nielsen Martin B. , Chaplin William J. , Ball Warrick H. , Davies Guy R. , Bedding Timothy R. , Buzasi Derek L. , Chontos Ashley , Huber Daniel , Kayhan Cenk , Li Yaguang , White Timothy R. , Cheng Chen , Metcalfe Travis S. , Stello Dennis 
Published: October 2022

Context. The Transiting Exoplanet Survey Satellite (TESS) mission has provided photometric light curves for stars across nearly the entire sky. This allows for the application of asteroseismology to a pool of potential solar-like oscillators that is unprecedented in size.
Aims. We aim to produce a catalogue of solar-like oscillators observed by TESS in the 120-s and 20-s cadence modes. The catalogue is intended to highlight stars oscillating at frequencies above the TESS 30-min cadence Nyquist frequency with the purpose of encompassing the main-sequence and subgiant evolutionary phases. We aim to provide estimates for the global asteroseismic parameters vmax and ∆v.
Methods. We applied a new probabilistic detection algorithm to the 120-s and 20-s light curves of over 250 000 stars. This algorithm flags targets that show characteristic signatures of solar-like oscillations. We manually vetted the resulting list of targets to confirm the presence of solar-like oscillations. Using the probability densities computed by the algorithm, we measured the global asteroseismic parameters vmax and ∆v.
Results. We produce a catalogue of 4177 solar-like oscillators, reporting ∆v and vmax for 98% of the total star count. The asteroseismic data reveal a vast coverage of the Hertzsprung-Russell diagram, populating the red giant branch, the subgiant regime, and extending towards the main sequence.
Conclusions. A crossmatch with external catalogues shows that 25 of the detected solar-like oscillators are a component of a spectroscopic binary, and 28 are confirmed planet host stars. These results provide the potential for precise, independent asteroseismic constraints on these and any additional TESS targets of interest.
Sarcopenia does not limit overall survival in patients with colorectal liver metastases undergoing interstitial brachytherapy
Authors: Thormann Maximilian , Heitmann Franziska , Wrobel Vanessa , Barajas Ordonez Felix , Pech Maciej , Surov Alexey , Damm Robert , Omari Jazan 
Published: October 2022

Purpose Several studies report an association of sarcopenia with survival in oncologic patients. The aim of this study is to assess the influence of sarcopenia on overall survival (OS) in patients with colorectal liver metastases undergoing interstitial brachytherapy (iBT)
Methods We identified 144 patients with colorectal liver metastases from our database from 2014–2017. Computed tomography (CT) chest scans at the L3 level were retrospectively analyzed. Psoas muscle area (PMA), psoas muscle index (PMI), and skeletal muscle gauge (SMG) were measured on the CT scan before treatment. Parameters were associated with overall survival.
Results 116 patients were included. Median overall survival was 27 months. Median PMA was 13.79 cm2, median PMI 4.51 cm2/m2. Neither PMA (HR 1.036, 95 % CI 0.996–1.078, p = 0.080), PMI (HR 1.068, 95 % CI 0.922–1.238, p = 0.382), nor SMG (HR 1.00, 95 % CI 0.998–1.003, p = 0.955) were significantly associated with overall survival.
Conclusion Sarcopenic patients undergoing iBT for colorectal liver metastases did not show decreased overall survival. If confirmed by comparative studies, sarcopenia may serve as a biomarker for treatment decision in patients with CRLM.
Key points: Sarcopenia is not a risk factor for survival in patients with CLRM undergoing iBT.
Citation Format
The impact of basic public services on residents’ consumption in China
Authors: Xiong Xing , Yu Xinghou , Wang Yuxin 
Published: October 2022

AbstractChina has the largest market potential in the world, but the resident consumption rate is relatively low. Releasing China’s consumption potential will contribute to the sustainable growth of China’s economy and the global economic recovery. Based on the supply of basic public services, this study analyzes the income and substitution effects of basic public services on residents’ consumption, with a view to finding channels and measures to stimulate residents’ consumption from the public sector. We first used the TOPSIS method of entropy weight to evaluate the public service level of 31 provinces in China, and then built a regression model to analyze the impact of public services on residents’ consumption, urban residents’ consumption, rural residents’ consumption, and the consumption gap between urban and rural residents. The study found that the improvement of public services has a significant positive effect on consumption, while public services also have a positive effect on narrowing the consumption gap between urban and rural residents, but the impact on urban and rural residents is different, and the positive effect on urban residents’ consumption is higher than that of rural residents. Based on the research results, this paper puts forward policy implications. On the one hand, we should increase the expenditure on basic public services, and on the other hand, we should optimize the layout of basic public services between urban and rural areas.
Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome
Authors: Vernia Santiago , Lee Alexandra , Kennedy Norman J. , Han Myoung Sook , Isasa Marta , Cavanagh-Kyros Julie , Roy Armanda , Syed Aafreen , Chaudhry Shanzah , Edwards Yvonne J. K. , Gygi Steven P. , Gao Guangping , Davis Roger J. 
Published: October 2022

The cJun NH
2
-terminal kinase (JNK) signaling pathway in the liver promotes systemic changes in metabolism by regulating peroxisome proliferator-activated receptor α (PPARα)-dependent expression of the hepatokine fibroblast growth factor 21 (FGF21). Hepatocyte-specific gene ablation studies demonstrated that the
Mapk9
gene (encoding JNK2) plays a key mechanistic role. Mutually exclusive inclusion of exons 7a and 7b yields expression of the isoforms JNK2α and JNK2β. Here we demonstrate that
Fgf21
gene expression and metabolic regulation are primarily regulated by the JNK2α isoform. To identify relevant substrates of JNK2α, we performed a quantitative phosphoproteomic study of livers isolated from control mice, mice with JNK deficiency in hepatocytes, and mice that express only JNK2α or JNK2β in hepatocytes. We identified the JNK substrate retinoid X receptor α (RXRα) as a protein that exhibited JNK2α-promoted phosphorylation in vivo. RXRα functions as a heterodimeric partner of PPARα and may therefore mediate the effects of JNK2α signaling on
Fgf21
expression. To test this hypothesis, we established mice with hepatocyte-specific expression of wild-type or mutated RXRα proteins. We found that the RXRα phosphorylation site Ser
260
was required for suppression of
Fgf21
gene expression. Collectively, these data establish a JNK-mediated signaling pathway that regulates hepatic
Fgf21
expression.
Implications of the non-observation of 6Li in halo stars for the primordial 7Li problem
Authors: Fields Brian D. , Olive Keith A. 
Published: October 2022

Abstract
The primordial Lithium Problem is intimately connected to the assumption that the 7Li
abundance observed in metal-poor halo stars is unchanged from its primordial value, which lies
significantly below the predictions of standard big-bang nucleosynthesis. Two key lines of
evidence have argued that these stars have not significantly depleted their initial (mostly
primordial) 7Li: i) the lack of dispersion in Li abundance measurements at low metallicity (and
high surface temperature); and ii) the detection of the more fragile 6Li isotope in at least two
halo stars. The purported 6Li detections were in good agreement with predictions from cosmic-ray
nucleosynthesis which is responsible for the origin of 6Li. This concordance left little room
for 6Li depletion, and the apparent 6Li survival implied that 7Li largely evaded destruction,
because stellar interiors destroy 6Li more vigorously then than 7Li. Recent (re)-observations
of halo stars challenge the evidence against 7Li depletion: i) lithium elemental abundances now
show significant dispersion, and ii) sensitive 6Li searches now reveal only upper limits to the
6Li/7Li ratio. We discuss the consequences of these 6Li non-detections on the primordial 7Li
Problem, Galactic cosmic-ray nucleosynthesis, and the question of differential depletion of Li in
stars. The tight new 6Li upper limits generally fall far below the predictions of cosmic-ray
nucleosynthesis, implying that substantial 6Li depletion has occurred — by factors up to 50. We
show that in stars with 6Li limits and thus lower bounds on 6Li depletion, an equal amount of
7Li depletion is more than sufficient to resolve the primordial 7Li Problem. This picture is
consistent with well-studied stellar models in which 7Li is less depleted than 6Li, and
strengthen the case that the Lithium Problem has an astrophysical solution. We conclude by
suggesting future observations that could test these ideas.
Primordial black hole from the running curvaton*
Authors: Liu 刘 Lei-Hua 磊华 
Published: October 2022

Abstract
In light of our previous study [Chin. Phys. C 44(8), 085103 (2020)], we investigate the possibility of the formation of a primordial black hole in the second inflationary process induced by the oscillation of the curvaton. By adopting the instability of the Mathieu equation, one can utilize the δ function to fully describe the power spectrum. Owing to the running of the curvaton mass, we can simulate the value of the abundance of primordial black holes covering almost all of the mass ranges. Three special cases are given. One case may account for dark matter because the abundance of a primordial black hole is approximately 75% . As late times, the relic of exponential potential may be approximated to a constant of the order of a cosmological constant, which is dubbed as the role of dark energy. Thus, our model could unify dark energy and dark matter from the perspective of phenomenology. Finally, it sheds new light on exploring Higgs physics.
6 OLDER ADULTS’ DECISION-MAKING CAPACITY FOR INDEPENDENT LIVING: OCCUPATIONAL THERAPY CONTRIBUTIONS TO COLLABORATIVE MULTIDISCIPLINARY ASSESSMENT
Authors: Usher R , Stapleton T 
Published: October 2022

Abstract

Background
Increasing age and life expectancy, alongside the growing prevalence of dementia-related diseases, indicate more older adults are likely to experience challenges regarding their decision-making capacity (DMC). The Assisted Decision Making (Capacity) Act 2015 provides a statuary framework for adults who are experiencing difficulties with decision-making and has implications for all healthcare professionals. Occupational therapists frequently contribute to multidisciplinary assessments of older adults’ DMC for independent living (IL).

Methods
Focus groups were conducted among occupational therapists working with older adults in Ireland to explore assessment practices of DMC for IL.

Results
Fifty-two occupational therapists, from a range of hospital and community settings, participated in nine focus groups. Therapists reported using enablement strategies and occupation-based approaches when assessing DMC to address the person’s values and preferences, cognitive-functional abilities and environmental needs for IL. However, resource issues and lack of shared understanding of DMC among the multidisciplinary team constrain DMC assessment practices. Furthermore, older people are often excluded from care-planning, and IL options are determined by availability of services rather than will and preference. Multidisciplinary education on DMC is essential in shaping a cohesive approach to assessment and to enhance older adults’ participation in decision-making.

Conclusion
Multidisciplinary collaboration and commitment to person-centred approaches may lead to enhanced outcomes for maximising and supporting older adult’s DMC regarding IL. A potential leadership role for occupational therapy in assessing DMC for IL is also highlighted.
13 FIGHTING FRAILTY FROM FOUNDATION UP
Authors: McKeown W , Kelly R , Eakin R , Hunter N 
Published: October 2022

Abstract

Background
In 2021 the UK Foundation Programme introduced a new curriculum for UK Foundation Doctors (FDs). For the first time, frailty has been designated as a core learning topic. This means that all FDs are expected to undertake dedicated frailty training. Subsequently, a virtual frailty workshop was developed and delivered by Zoom to all F2 doctors in Northern Ireland. Entitled ‘Taking a Better Approach to the Frailer Adult’, the three hour workshop familiarises FDs with core frailty concepts including Comprehensive Geriatric Assessment (CGA), delirium, and deprescribing.

Methods
All attendees completed an online survey after workshops. They were asked to provide free text comments about what they felt were the most successful and useful aspects of the workshop. Attendees were also were asked to numerically rate the workshop relevance, handout quality and venue suitability.

Results
The frailty workshop was delivered to 222 F2 doctors over eight months. On average, attendees rated the relevance of the workshop as 4.8/5. Attendees rated the quality of the handouts and the venue suitability at 4.4/5 and 4.2/5 respectively. Thematic analysis of qualitative feedback on the most successful elements of the workshop showed that attendees found the session to be useful, relevant, and engaging, with particular preference for use of cases. For example, one attendee wrote that, ‘use of cases and breakout rooms to discuss CGA [allowed] us to get a feel of how this applies to patients in clinical settings”. Thematic analysis of qualitative feedback on what could be done to make the workshop better showed attendees had preferences for greater use of cases and smaller breakout rooms. This feedback was used to develop and improve the workshop.

Conclusion
FDs value teaching on frailty and consider it highly relevant for clinical practice. Frailty education can be delivered successfully in a virtual setting. Junior doctors prefer interactive case based learning, with use of breakout rooms with small numbers of participants in each room.
25 EVALUATION OF PATIENTS PRESENTING WITH TIA IN THE AMAU AND TIA FAST ASSESSMENT CLINICS - ARE WE MEETING ESO GUIDELINES?
Authors: Hearne S , Costelloe R , Murphy S , Kelly P , McGorrian C , Marnane M 
Published: October 2022

Abstract

Background
The European Stroke Organisation published guidelines on the management of Transient Ischaemic Attack (TIA) in 2021. Specialist review of suspected TIA is recommended within 24-hours of symptom onset in a TIA clinic. They suggest using CT or MR angiogram for additional confirmation of large artery stenosis of &gt;50%. They advise against the use of prediction tools alone e.g. ABCD2 score when identifying high-risk patients. Dual antiplatelet therapy is recommended short-term in high risk, non cardio-embolic TIA patients. This audit evaluates if these guidelines are being followed in our institution.

Methods
We evaluated all patients attending the TIA clinic and the Acute Medical Assessment Unit (AMAU) with suspected TIA over a three-week period in 2021 in a single tertiary referral centre. Retrospective data was collected based on chart review.

Results
Twenty patients underwent review in the TIA clinic and eight in the AMAU with suspected TIA in the chosen time period. One patient (3.5%) was seen within 24 hours from symptom onset, 2 were seen within 24-36 hours (7.1%), 4 patients (14.2%) were seen within 36-72 hours, 21 patients (75%) were seen &gt;72 hours after symptom onset. In all patients who had a doppler US showing &gt;50% carotid stenosis, a CT angiogram was performed. ABCD2 scores were recorded but used in combination with clinical judgment. All patients with high-risk, non-cardioembolic TIA received early, short-term dual antiplatelet therapy.

Conclusion
The diagnostic methods and treatment strategies in place for patients attending the TIA clinic or AMAU with TIA were in keeping with the recently published ESO guidelines. However, there was a time delay from symptom onset to time of review in many patients. Further studies are indicated to identify the potential mechanisms behind these delays. Interventions to ensure that we are meeting this ‘time-to-review’ target in patients could be implemented, ensuring high quality, evidence-based care.
30 THE DIAGNOSTIC AND PREDICTIVE ACCURACY OF THE EDMONTON FRAIL SCALE FOR SCREENING FRAILTY IN OLDER ADULTS: A SYSTEMATIC REVIEW AND META-ANALYSIS
Authors: Hynes C , Galvin R 
Published: October 2022

Abstract

Background
Frailty is a dynamic, multidimensional syndrome that is highly prevalent in older adults (65 years or older), which increases one’s dependency and vulnerability to adverse health outcomes, including mortality. The Edmonton Frail Scale (EFS) is a commonly used screening tool for identifying frailty in older adults.
The purpose of this systematic review and meta-analysis is to determine the diagnostic test accuracy of the EFS to identify frailty in older adults, as well as the predictive accuracy of the EFS for adverse outcomes associated with frailty.

Methods
A literature search was performed across PubMed, EMBASE, CINAHL, MEDLINE and the Cochrane Library to identify all studies that validated the EFS across clinical settings. The methodological quality of the included studies was assessed using the QUADAS-2 tool. A bivariate random effects model generated pooled estimates of sensitivity and specificity.

Results
Eleven studies were included in the systematic review and six studies were included in meta-analysis. The diagnostic test accuracy of the EFS could not be proven from the included studies. The EFS was found to be more useful at ruling in rather than ruling out increased risk of mortality in individuals classified as frail, with a higher pooled specificity (0.75, 95% CI 0.64-0.84) than sensitivity (0.49, 95% CI 0.42-0.56).

Conclusion
The Edmonton Frail scale has limited ability as a frailty screening tool and should not be used in isolation to screen for frailty in older adults in clinical settings.
39 CAN BEHAVIOURAL CHANGE INTERVENTIONS IMPROVE SELF-EFFICACY AND EXERCISE ADHERENCE AMONG PEOPLE WITH PARKINSON’S? A SYSTEMATIC REVIEW
Authors: Ahern L , Timmons S , Lamb S , McCullagh R 
Published: October 2022

Abstract

Background
People with Parkinson’s (PwP) lead sedentary lifestyles compared to healthy peers. Personal influences including low self-efficacy and poor outcome expectation appear to predict exercise adherence more accurately than disease severity. The purpose of this review is to identify successful behavioural-change interventions that promote self-efficacy and exercise adherence among PwP.

Methods
Databases including EBSCO, Medline, CINAHL, Web of Science, PubMed, Embase, Scopus, Google Scholar and Cochrane Library were searched from inception to 2020. Interventional studies including a behavioural-change intervention were included. Title, abstract and full-text screening was conducted by two independent reviewers. The Cochrane Risk of Bias Tool and Robins-I were used to assess the Risk of Bias. Data was extracted by two independent reviewers. The outcomes of interest were self-efficacy, quality of life, physical function, and exercise adherence. A narrative synthesis was completed and mapped to the Theoretical Domains Framework, to produce practice-orientated outcomes.

Results
Seventeen studies (n=1319) were included. Risk of bias was generally moderate. A multicomponent behavioural-change intervention encompassing education, behavioural strategies and support groups appeared to improve quality of life, physical function, and exercise adherence in PwP. No intervention improved self-efficacy. Self-monitoring, goal setting, social supports, feedback, self-managements skills and action planning improved long-term adherence.

Conclusion
No intervention changed self-efficacy. However, it appears that a multicomponent intervention is essential to improve exercise adherence. Trials directly comparing different intervention types and adequate follow-up periods are limited, preventing a conclusive finding of the most effective behavioural-change intervention to promote exercise adherence among PwP.
43 EXPLORING STAFF PERCEPTIONS AND ATTITUDES TO CARE AND CAREBOTS: THE CASE OF AN ORIGINAL AIR-DISINFECTION ROBOT IN IRELAND
Authors: Kodate N , Kohli P , McGinn C , Scott R , Ross E , Treusch P , Maeda Y , Donnelly S , Leonard C , Cogan L , Mannan H , O’Shea D , Obayashi K , Masuyama S 
Published: October 2022

Abstract

Background
The pandemic heightened the sense of security and safety in care settings, with cleanliness and infection control becoming an even more important aspect of care delivery. Although the impact of new welfare technology on health and social care has been discussed in recent years, few studies have reported the implementation processes or human-robot interactions in care facilities in different cultural settings. The aims of this interdisciplinary research therefore were to understand needs and aspects that have to be considered for implementing an assistive robot, and to explore user perceptions, and the process by which the robots are adopted in Ireland and Japan.

Methods
An original air-disinfection robot (V-Air) was developed by Akara Robotics, as part of research project “Harmonisation towards the establishment of Person-centred, Robotics-aided Care System” (Toyota Foundation, D18-ST-0005). Prior to its instalment in a rehabilitation centre in Dublin, semi-structured interviews were conducted, and observations carried out with seven care professionals, as they interacted with V-Air. The robot was then trialled for eight weeks (March-May 2022) in selected areas of the facility. After four weeks, the users filled out the System Usability Score and were asked questions at the end of the trial. Their scores and answers to the questions revealed staff perceptions and attitudes to care robots.

Results
Overall, the users had positive perceptions of V-Air and its usability. Initial differences existed in staff’s confidence levels, depending on prior experiences with technologies. Collective sensemaking was observed, particularly, around care delivery processes and robot functionalities. The adoption process was facilitated by several factors such as the timing of introduction, user-centred design, concept of care and organisational support.

Conclusion
The findings suggest that the introduction of care robots in care settings can offer an additional layer of organisational safety, while highlighting the significance of the iterative process in adopting assistive technologies.