bluuebunny/crossref_metadata_2025_split huggingface dataset:
Are scrubs really protecting?
Authors: Suleman Fatima 
Published: May 2022

Madam, surgical site infections are a major cause of postoperative morbidity and mortality and have long been a matter of concern. In the early twentieth century, surgeons were allowed to wear their clothes in the operating room (OR). After it was discovered that the surgical attire could be a source of these infections, surgical scrubs were introduced [1]. With the advent of the COVID-19 pandemic, many hospitals changed their policies, requiring healthcare workers to wear scrubs in wards, special care units (SCU), and intensive care units (ICU) due to their encounters with patients. This measure was taken to protect the healthcare personnel from the virus and t ensure that their contaminated clothing did not become a vector of infection to their families and society. The change was quickly adopted particularly in the private sector, due to the free provision of scrubs by the hospital, hospital-laundering facilities, increased comfort and feasibility of the professionals, and most importantly, for the sake of their own and their families’ safety [2]. The issue arose when doctors were observed wearing the same surgical scrubs in the operating room as they did elsewhere in the hospital. Patients admitted at SCU and ICU are infected with multidrug-resistant and extensively drug-resistant microbes, and wearing scrubs contaminated with these organisms in the operating room can be extremely dangerous. Though many hospitals encourage wearing gowns or white coats over the scrubs outside the OR, there is no evidence that it prevents contamination. According to observations and studies, professionals wear white coats even outside the hospital, and are more contaminated by multidrug-resistant organisms. The extent of contamination depends at the type of fabric, antimicrobicidal coating, and the laundering frequency [3]. The national guidelines for infection prevention and control need to be more precise regarding the surgical attire inside and outside the OR, and it should ensure implementation at every hospital. It is suggested that the colour of the scrubs worn inside and outside the OR be different, surgical scrubs should be provided to all healthcare staff by the hospital, and no one should be allowed to wear his personal scrubs inside the hospital. All professionals should be provided lockers, and wearing surgical scrubs outside the hospital should be prohibited. More frequent audits during the pandemic should be done to ensure the safety of the healthcare workers and patients [4].
Eine Arche Noah für Pflanzen
Authors: Schaal René 
Published: May 2022

Frankfurt a.M. Das beschauliche Longyearbyen auf der norwegischen Insel Spitzbergen wurde Anfang des vergangenen Jahrhunderts als Bergarbeitersiedlung gegründet. Die etwas mehr als 2000 Einwohner können sich rühmen, in der nördlichsten Gemeinde der Erde zu leben – und Heimat der weltweit größten Saatgutsammlung zu sein.
Seropositivity of Toxoplasma gondii antibodies in rheumatoid arthritis patients under treatment with TNF-? antagonists
Authors: Dreaj Hadeel Abed , Hathal Huda Dhaher , Hassan Abbas Ahmed Abdul 
Published: May 2022

Introduction and Aim: Rheumatoid arthritis an autoimmune disease is the most frequent kind of inflammatory arthritis and a leading cause of disability in the United States. The study's goal was to determine whether or not individuals with Rheumatoid Arthritis were positive for Toxoplasma antibodies while receiving biological therapy.

Materials and Methods: By ELISA method Toxoplasma antibodies were investigates in serum of 100 RA patients under treatment with TNF-? antagonist from 4-6 months, and in serum from 100 healthy controls.

Results: A statistically significant difference was found between patients and controls in the proportion of Toxoplasma antibodies (IgM 6, IgG 16 positive individuals). There was no correlation identified between Toxoplasma antibody seropositivity and responsiveness to biological treatments or disease activity.

Conclusion: Toxoplasma antibody seropositivity may be associated with rheumatoid arthritis among Iraqi patients under biological drugs.
The potential of social and pedagogic design for training future teachers to their professional activity
Authors: Кибальник А.В. , Федосова И.В. 
Published: May 2022

В статье исследован потенциал социально-педагогического проектирования в подготовке будущих педагогов к профессиональной деятельности: формирование субъектной позиции личности, умение критически оценивать результаты профессиональной деятельности, способности конструирования и моделирования условий социальной среды с использованием педагогических средств для получения общественно-ценного продукта. На основе теоретического анализа психолого-педагогической литературы выявлены критерии (мотивационно-ценностный, деятельностный, индивидуально-личностный, рефлексивный) и показатели готовности будущих педагогов к профессиональной деятельности, а также подобран диагностический инструментарий исследования. В результате представлена модель подготовки будущих педагогов к профессиональной деятельности через социально-педагогическое проектирование, состоящая из трех взаимосвязанных блоков: установочно-целевой, представляющий цели и задачи модели; организационно-деятельностный, реализующийся в процессе формальной и неформальной образовательной деятельности; оценочно-аналитический, включающий ряд рефлексивных приемов.
The article issues the potential of social and pedagogic design for training future teachers to their professional activity: the forming of personality’s subject position, skill of critical assessment of the results of one’s own professional activity, ability to design and model the conditions of social environment using pedagogic means to obtain socially valuable product. Based on theoretical analysis of psychological and pedagogic literature, the authors worked out the criteria (motivation, value, activity, personal and reflective criteria) and indices of future teachers’ preparedness to professional activity and, in addition, selected diagnostic tools for research. The result is a model of training future teachers for professional activity through social and pedagogic projecting. The model consists of 3 inter-related sections: aim and direction section representing goals and tasks of the model; organizational and activity section, implemented during formal and informal education activity; finally, assessment and analytical block including a number of reflective techniques
Features of the world image of older
Authors: Додзина О.Б. 
Published: May 2022

Статья посвящена актуальной проблеме образа мира, являющемуся ориентировочной основой познания и социального взаимодействия. Уточнение данных об особенностях образа мира лиц с ОВЗ имеет первостепенное значение для понимания своеобразия их познавательного, личностного развития и социализации. Цель статьи определить особенности образа мира старших дошкольников с задержкой психического развития. В исследовании была использована методика «Детский образ мира» (ДОМ) С.А. Домишкевича. Было установлено, что представления о мире старших дошкольников с задержкой психического развития несмотря на их относительную полноту, не функциональны, слабо обобщены и не имеют тенденции к интеграции. Исследование эмоционально-ценностного аспекта образа мира старших дошкольников с задержкой психического развития выявило сочетание эмоционально положительного отношения к компонентам образа мира, связанным с игрой, отдыхом и, одновременно с этим, отсутствие позитивного интереса к школе и обучению. В исследовании установлено, что образ мира старших дошкольников с задержкой психического развития не обладает целостностью, то есть представляет собой отдельные не связанные между собой образы, каждый из которых ограничен чувственными, непосредственно воспринимаемыми компонентами. Эмоционально-ценностный компонент усиливает дефицитарность функционирования образа мира старших дошкольников с задержкой психического развития, так как препятствует развитию познавательной потребности, решению социальных задач взросления, фиксирует личностную незрелость.
The article is devoted to the actual problem of the world image, which is the indicative basis of cognition and social interaction. Clarification of data on the features of the world image of persons with disabilities is of paramount importance for understanding the originality of their cognitive, personal development and socialization. The purpose of the article is to determine the features of the world image of older preschoolers with mental retardation. The study used the technique "Children's world image" (DOM) S.A. Domishkevich. It was found that therepresentations about world of older preschoolers with mental retardation, despite their relative completeness, are not functional, poorly generalized, and do not tend to integrate. The study of the emotionally significant aspect of the world image of older preschoolers with mental retardation revealed a combination of an emotionally positive attitude to the components of the world imageassociated with play, recreation and, at the same time, a lack of positive interest in school and learning. The study found that the world image of older preschoolers with mental retardation does not have integrity, that is, it represents separate unrelated representations, each of which is limited by sensory, directly perceived components. The emotionally significant component enhances the deficiency in the functioning of the world imageof older preschoolers with mental retardation, as it prevents the development of a cognitive need, the solution of social problems of growing up, and fixes personal immaturity.
The method of sand therapy in working with the emotional sphere of a person who is faced with a difficult life situation during a pandemic
Authors: Полянская Е.Н. , Каргина Н.В. 
Published: May 2022

Статья посвящена проблеме эффективных методов в работе с эмоциональной сферой человека, столкнувшимся с трудной жизненной ситуацией в период пандемии. Современные реалии с пандемией и как следствие нестабильная экономическая ситуация вынуждает человека находиться в напряжении, состоянии стресса и фрустрации. Потеря работы, переход на дистанционное обучение и работу, болезнь, смерть близких людей и т.д. и т.п. Не многие находят в себе силы для того, чтобы пережить негатив и найти необходимые ресурсы для адаптации в новых условиях. Чаще всего негативные эмоции человека настолько сильны, что «захватывают» его полностью, мешая думать и принимать решения.Авторами проведено экспериментальное исследование с испытуемыми, оказавшимися в трудных жизненных ситуациях, был использован метод песочной терапии.В результате авторы приходят к выводу, что метод песочной терапии является эффективным методом для работы с эмоциональной сферой человека.
The article is devoted to the problem of effective methods in working with the emotional sphere of a person who is faced with a difficult life situation during a pandemic. Modern realities with a pandemic and, as a result, an unstable economic situation force a person to be in tension, a state of stress and frustration. Job loss, transition to distance learning and work, illness, death of loved ones, etc. etc. Not many find the strength in themselves to survive the negative and find the necessary resources to adapt to the new conditions. Most often, a person’s negative emotions are so strong that they “capture” him completely, making it difficult to think and make decisions.The authors conducted an experimental study with subjects who found themselves in difficult life situations, the method of sand therapy was used.As a result, the authors come to the conclusion that the method of sand therapy is an effective method for working with the emotional sphere of a person.
Practical teaching of pathophysiology to LAFFH at the IPD outpatient clinic of FMP/FASE: Historical Report
Authors: Martins Cláudio Hansel , Sperduto Victor Tito , Bernardo Roberta Malher , Pires Thaís Ferreira do Espírito Santo , Varricchio Marcia Cristina Braga Nunes 
Published: May 2022

Background: Undergraduate students of UNIFASE/FMP, through the Academic League of Human Physiology and Pathophysiology (Liga Acadêmica de Fisiologia e Fisiopatologia Humana - LAFFH), participate in a supervised internship to outpatient at the Infectious and Parasitic Diseases Service of FMP/FASE, authorized by Clinical Direction (October 2018). Patients received conventional therapy in addition to complementary therapy with Homeopathy, for external use for cleaning skin lesions and modulating inflammatory responses, whose mechanisms of action are already described in the scientific literature and authorized by ANVISA. Aims: Make approach of undergraduate students to Homeopathic pathophysiology. Methodology: The supervised clinical internship of LAFFH students is in two service rooms with 6 students in each, based on prior appointment due to spontaneous demand, with medical records registered by the IPD outpatient service secretary. Outpatient clinical care addresses the pathophysiology and miasms of the symptoms and signs of neglected chronic parasitic diseases prevalent in our country, identified by anamnesis and physical examination. They are correlated to biological activities in plant chemistry classes, besides official homeopathic pharmacopoeia. So, it was adopted the external use of HUD Ledum palustre 6ch for the cleansing of skin lesions with torpid evolution at IPD. Results and discussion: Two patients with edema and varicose ulcers were treated with the ointment offered. Edema extension which was +++/4+ to both patients diminished to +/4+ in 30 days of interval. Indeed, ulcers remained at the same shape and size, but their bases were cleaned, without purulence. Novel clinical sessions did not occur because of social distancing needed. Conclusion: It has been developed a positive perception among patients and students about the action of homeopathic remedies. The practical teaching activity initiated encourages students in clinical reasoning about complementary therapeutic association with Homeopathy for patients whose evolution is below the expected prognosis with conventional therapy. Project of clinical observation will be elaborated to research ethics committee.
Viscum album L. homeopathic mother tinctures: Metabolome and antitumor activity
Authors: Melo Michelle Nonato de Oliveira , Oliveira Adriana Passos , Garrett Rafael , Zancan Patrícia , Ochioni Alan Clavelland , Grazi Mirio , Ramm Hartmut , Jaeger Tim , Baumgartner Stephan , Holandino Carla 
Published: May 2022

Background: Viscum album L. is a semi-parasitic plant with antitumor activity attributed to the aqueous extracts. However, European V. album ethanolic extracts (VAE) have also demonstrated in vitro activity in tumor models. Aims: Evaluate the metabolic profiles of fifty VAE harvested during summer and winter seasons and their antitumor activity through 2D and 3D models. Methodology: VAE were prepared by maceration from: V. album subsp. album growing on Malus domestica, Quercus sp. and Ulmus sp.; V. album subsp. austriacum from Pinus sylvestris; V. album subsp. abietis from Abies alba. Chemical analyses were performed through liquid chromatography coupled with high resolution mass spectrometry and Partial Least Squares Discriminant Analysis (PLS-DA) was performed in the Metaboanalyst 4.0. The antitumor potential of the selected VAE was evaluated in 2D and 3D models (MDA-MB-231 cancer cells) by MTT, crystal violet and glycolytic pathway analysis. Results and discussion: The first 3 principal components in PLS-DA explained 60% and 40% of data variation in positive and negative modes respectively. Three groups were formed and showed chemical similarity among V. album subspecies. The compounds responsible for group separation were tentatively identified as: pinobankasin or naringenin hexoside; isorhamnetin-3-hexoside, meglutol and different amino acids. The summer VAE at 0.5% v/v induced higher cytotoxic damage than the winter preparations, and Abies alba and Quercus sp. VAE promoted 49% and 42% reduction of tumor viability in 3D model (72h incubation), respectively. MDA-MB-231 glycolytic pathway in 2D model showed a decrease in the glucose consumption and extracellular lactate production. Also, PFK (6- phosphofructo-1-kinase) and PK (Pyruvate kinase) activities were inhibited by Abies alba and Quercus sp. VAE at 48h of incubation. Conclusion: VAE extracts showed different metabolomes and the glycolytic pathway should be an important target involved in the inhibition of tumor growth by these extracts.
Health Technology Assessment in Tanzania: Capacity and experience of HTA committee members
Authors: Surgey Gavin , Mori Amani T , Baltussen Rob 
Published: May 2022

Background Tanzania established a Health Technology Assessment Committee in recognition of the increasing role of Health Technology Assessment (HTA) to achieve universal health coverage. The committee has the mandate to develop recommendations on the reimbursement of technologies for decision-makers. It is widely recognized that there are challenges to the technical capacity and human resource availability of HTA, including that of decision-making committees. Committee members need to combine scientific and social judgments vis-a-vis the technology under evaluation. This paper reports on a self-administered survey among committee members to assess their capacity for the tasks at hand. Methods A survey was developed and sent to all members of the HTA committee in Tanzania. Responses were analyzed, and key themes explored. Results Out of 20 committee members, 15 members completed the survey (response rate 75%). Committee members were primarily government employees who were qualified and well-experienced in clinical medicine. However, they were less qualified and experienced in HTA and expressed low confidence in this subject matter. Conclusions The results indicate the type of evidence an advisory committee can reasonably be expected to understand and handle. It can also guide future capacity-strengthening activities and programmes, and serve as a baseline for measuring the impact of these programmes.
UPAYA MENINGKATKAN KEMAMPUAN MEMBACA, MENULIS DAN MENGHITUNG MELALUI REMEDIAL TEACHING BAGI ANAK TUNAGRAHITA RINGAN DI WISMA PAULO 6 YAYASAN BHAKTI LUHUR MALANG
Authors: Wahyuni Sri , Muliati Florentina 
Published: May 2022

Anak tunagrahita ringan adalah anak tunagrahita yang tidak mampu mengikuti program sekolah biasa tetapi ia masih memiliki kemampuan yang dapat dikembangkan melalui pendidikan khusus. Remedial Teaching adalah suatu layanan pendidikan atau suatu bentuk program pembelajaran yang dilaksanakan dengan perlakuan khusus yang diberikan guru pada siswa yang mengalami kesulitan dan hambatan dalam kegiatan belajar mengajar sehingga siswa tersebut mencapai standar kompetensi yang telah ditentukan. Penelitian ini bertujuan untuk mengetahui apakah remedial teaching dapat meningkatkan kemampuan membaca menulis dan menghitung bagi anak tunagrahita ringan di Wisma Paulo 6 Yayasan Bhakti Luhur Malang. Penelitian ini menggunakan rancangan penelitian deskriptif kuantitatif, dengan subjek 2 orang anak tunagrahita ringan. Metode yang digunakan adalah observasi partisipan penuh. Sedangkan analisa data dilakukan dengan membandingkan tes awal dan tes akhir. Sesuai dengan tujuan upaya meningatkan kemampuan membaca menulis dan menghitung bagi anak tunagrahita ringan maka diperoleh hasil sebagai berikut: untuk responden MZ latihan membaca nilai pre testnya 5 nilai post tesnya 8, jadi ada kemajuan 3 poin. Untuk latihan menulis nilai pre tesnya 5 dan nilai post tesnya 9, jadi ada kemajuan 4 poin. Untuk latihan menghitung nilai pre tesnya 5 dan hasil post tesnya sebesar 8 jadi ada kemajuan 3 poin. Untuk responden AG latihan membaca nilai pre tesnya 5 dan nilai post tesnya 9 jadi ada kemajuan 4 poin. Untuk latihan menulis nilai pre tesnya 5 dan nilai post tesnya 9, jadi ada kemajuan 4 poin. Untuk latihan menghitung nilai pre tesnya dan hasil post tesnya 8 jadi ada kemajuan 3 poin.
Avaliação da aprendizagem: como vivenciá-la numa perspectiva de construção do conhecimento?
Authors: Santos Zelia Maria , Cavalcanti Rilva José Cavalcanti , Pereira José 
Published: May 2022

Um dos grandes desafios da educação é a avaliação da aprendizagem, pois embora muito se tenha escrito a este respeito, é possível encontrarmos nas escolas a velha prática do exame, que tem como finalidade classificar. Então, neste artigo temos como objetivo diferenciar exame de avaliação, como também, compreender a avaliação na perspectiva da construção do conhecimento. Para esta discussão trazemos o que pensam alguns autores como Bechara (2009), Saul (2010), Luckesi (2011) Romão (2011),), Sant’Anna (2014) e Oliveira e Batista Neto (2017), bem como, um relato de experiência vivenciado em sala de aula alusivo à avaliação dialógica e consequentemente voltada para a construção do conhecimento, evidenciando, dessa forma, o erro do estudante como subsídios às novas aprendizagens, uma vez que a filosofia do professor está direcionada para a construção significativa do saber.
El may pole en la memoria de los portadores culturales creoles de Puerto Cabezas, Región Autónoma de la Costa Caribe Norte de Nicaragua
Authors: Lee Smith Dixie Dean , Rojas Hooker Sandra Carolina 
Published: May 2022

Este artículo titulado El may pole en la memoria de los portadores culturales creoles de Puerto Cabezas, Región Autónoma de la Costa Caribe Norte de Nicaragua, alude a la danza caribeña palo de mayo y se han enfatizado los ritos asociados a la celebración de esta festividad que, representa un reencuentro con nuestras raíces históricas y culturales. La metodología es cualitativa con enfoque hermenéutico al basarse fundamentalmente en bibliografía y las entrevistas realizadas, el nivel de profundidad es descriptiva-explicativa ya que permitió reconstruir la memoria sobre lo andado y vivido y extraer las lecciones aprendidas o la experiencia de los portadores culturales afrodescendientes en la promoción y preservación del may pole en Puerto Cabezas. Al compartir sus conocimientos, saberes y prácticas los portadores culturales nos brindan la posibilidad de rescate del verdadero significado de la festividad y la revitalización de la misma en espacios privados y públicos.
Relationship of plasma homocysteine, soluble intercellular adhesion molecule-1, high mobility group box 1 protein with carotid intima-media thickness in elderly patients with type 2 diabetes mellitus
Authors: Cai Zhijie , Xue Jun , Ma Xiaohui , Chen Peifeng , Ge Biao , Zhang Yuying , Dong Zhihui 
Published: May 2022

Objective: To explore the relationship of plasma homocysteine (Hcy), soluble intercellular adhesion molecule-1 (sICAM-1) and high mobility group box 1 protein (HMGB1) with carotid intima-media thickness (c-IMT) in elderly patients with type 2 diabetes mellitus.Methods: A total of 100 elderly patients who were diagnosed as type 2 diabetes mellitus in Baogang Hospital of Inner Mongolia from June 2017 to May 2020 were chosen as research objects. According to c-IMT, they were divided into the normal group (n = 35), the mild to moderate group (n = 41) and the severe group (n = 24). The expression levels of plasma Hcy, sICAM-1 and HMGB1 were compared between groups respectively. Pearson’s correlation coefficient was used to analyze the relationship of plasma Hcy, sICAM-1, HMGB1 with c-IMT.Results: The comparison in plasma Hcy, sICAM-1, HMGB1 and c-IMT among the three groups of patients was of statistical significance (p < .05). The results of correlation analysis showed that the expression levels of plasma Hcy, sICAM-1 and HMGB1 were positively correlated with c-IMT in elderly patients with type 2 diabetes mellitus (r = .627, .598, .614; p < .05).Conclusions: The expression levels of plasma Hcy, sICAM-1 and HMGB1 are abnormally increased in elderly patients with type 2 diabetes mellitus, and related to c-IMT, which can provide a strong evidence for clinical diagnosis and treatment by detecting their levels in clinical practice.