bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fenologi Bunga Zinnia sp dan Potensinya Sebagai Refugia Pada Tanaman Cabai (Capsicum annum)
Authors: HARAHAP WAHYUNI UMAMI , Fadhillah Wizni , Intan Dian Retno 
Published: November 2022

Budidaya tanaman cabai di Indonesia saat ini sangat bergantung terhadap penggunaan pestisida sintetik. Pestisida sintetik sangat buruk terhadap kelestarian lingkungan seperti berkurangnya jumlah dan jenis musuh alami. Kondisi tersebut mendorong penemuan teknik pengendalian hama dan penyakit yang lebih ramah lingkungan seperti penggunaan refugia. Refugia yang sering digunakan adalah Zinnia sp. Namun morfologi Zinnia sp belum banyak diketahui terutama tentang penologi bunga sehingga sulit menentukan waktu penanaman yang tepat agar efektif dalam mengendalikan hama. Hal ini yang menjadi dasar dilakukannya penelitian penggunaan refugia Zinnia sp pada tanaman cabai. Penelitian ini dilakukan dengan penanaman refugia Zinnia sp sebanyak 20 tanaman di setiap pinggir bedengan. Pengamatan dilakukan dengan mengamati perkembangan bunga Zinnia sp setiap hari serta mengidentifikasi hama dan musuh alami. Berdasarkan hasil pengamatan diketahui serangga menyukai bunga Zinnia sp pada fase X sampai XII. Hama yang ditemukan pada lahan adalah orong-orong (Gryllotalpa sp.), lalat pengorok daun (Liriomyza sp.), kutu kebul (Aphis craccivora), trips (Thrips spp.), tungau (P. latus), lalat buah (Bactrocera spp.). Musuh alami yang ditemukan pada lahan adalah Hemiptarsenus varicornis, Eriborus argenteopilosus, Menochilus sexmaculatus. Kesimpulan yang dapat diambil dari penelitian ini adalah Zinnia memiliki potensi yang tinggi untuk digunakan sebagai refugia dan penanaman Zinnia sp sebaiknya dilakukan satu bulan lebih awal dari penanaman cabai.
Phenomenon of Fasting in the Early Christian Anglo-Saxon Tradition
Authors: Proskurina A. V. 
Published: November 2022

: The Old English poem Seasons for Fasting was written in the X century and consists of 230 lines. This article describes it through the prism of fasting in the Old English tradition. Like any other Old English Christian sermon, Seasons for Fasting focused on the moral rules of Christian life. It represented the first procedures for seasonal fasts. The author translated the poem and performed an interdisciplinary study of the phenomenon of fasting against the background of the indisputable position of faith in the Anglo-Saxon culture. The Old and New Testaments, as well as the Indo-European myths, showed the deep cultural interconnection of archaic traditions. A detailed idea of divinely revealed truth was reflected already in the earliest Christian texts where references to commandments from the Old Testament intertwined with the moral principles of the New Testament. The goal of the study was to determine the complex nature of the traditional methods used for philological analysis of texts and the semiotic approach to texts. The view of food as sacred and profane was manifested already at the early stages of the religious consciousness development. Traditionally, fasting issues were considered as part of prayer appeals. Seasons for Fasting stressed the New Testament idea that sinners could not enter the Kingdom of God without repentance and awareness of their unrighteous life. The paper highlights the symbolism of fire, mountains, cosmos, sacrifice, submersion, burial, and the Kingdom of Heaven. The article also provides a list of variant addresses to God used in the poem: the Old English period saw a well-developed Christian tradition, which had no direct naming for the devil.
Procedure for the Semisyntheses of Peptide Amides having a Glutamic or Aspartic Acid a-Amide at the C-terminal
Authors: Rolland Marc , Henriksen Dennis B. , Breddam Klaus , Buchardt Ole 
Published: November 2022

Abstract:
Various protected aspartic acid ex-amide and glutamic acid ex-amide derivatives were synthesized and applied as nucleophiles in transacylation reactions using carboxypeptidase Y. The benzyl, tert-butyl, cyclohexyl and cyclopentyl ester-type protection for the carboxyl groups were examined and deprotection were achieved by conventional methods.
Self assembling peptides exhibiting antithrombotic activity
Authors: Puvanakrishnan R. , Ramesh C.V. , Jayakumar R. 
Published: November 2022

Abstract:
Peptides viz. Boc-L-Arg-L-Pro-lauryl ester laurate (I), Boc-L-Arg-L-Pro-L-Pro-lauryl ester laurate (II) and Boc-L-Arg-L-Pro-stearyl ester stearate (III) were tested in vitro for anticoagulant and fibrinolytic activity. Peptide III was also tested for induction oftissue-plasminogen activator release in a rat model, measured ex vivo. Among the peptides tested, III was found to be more potent than I and II. The peptides tended to aggregate in aqueous solutions, and in this aggregated state, the peptides could exhibit the biological activities.
Enzymatic Properties Of A-Mannosidase From
Trichoderma Reese
Authors: Neustroev Kirill N. , Kulminskaya Anna A. , Eneyskaya Elena V. , Isaeva-lvanova Ludmila S. , Shabalin Konstantin A. , Savel'ev Andrew N. , Backinowsky Leon V. , Abronina Polina I. 
Published: November 2022

Abstract:
Kinetic parameters of reactions catalyzed by a-mannosidase from Trichoderma reesei were determined using various mannooligosacharides as substrates. These reactions were found to go with retention of anomeric configuration. Kinetic experiments revealed the existence of a functionally significant SH-group in the active site of the enzyme. A transglycosylating activity toward p-nitrophenyl-a-D-mannopyranoside was found and single product of this reaction was identified as p-nitrophenyl-a-D-al 2 mannopyranosyl-a-D-mannopyranose.
Use Of 1-β-Naphthalenesulfonyloxybenzotriazole As Coupling Reagent For Peptide Synthesis In The Presence Of Fluorinated Alcohols As Cosolvent
Authors: Khare Sanjay K. , Singh Geeta , Agarwalb Kamlesh C. , Kundu Bijoy 
Published: November 2022

Abstract:
Solution Phase synthesis of peptides in solvents mixed with fluorinated alcohols have been carried out using 1-B-Naphthalenesulfonyloxybenzotriazole (NSBt) as coupling reagent.
Crystallization and preliminary x-ray analysis of sm-spm, a phospholipase A2 isolated from the venom of bothrops jararacussu
Authors: de Azevedo Walter F. , Fontes M. R. M. , Ward Richard J. , Lombardi F. R. , Cintra A. C. O. , Giglio Jose R. , Arni Raghuvir K 
Published: November 2022

Abstract:
Large single crystals have been obtained of Srn-SPm, a phospholipase A2 from the venom of Bothrops Jararacussu. The crystals belong to the orthorhombic system space group C222, and diffract X-rays to a resolution of I.9 A. Preliminary analysis reveals the presence of one molecule in the crystallographic asymmetri9 unit. The crystal structure is currently being determined using molecular replacement techniques.
Effects of Gene Dosage on the Expression of a Functionally Active C-Terminal Domain of Human Mucus Proteinase Inhibitor in E. Coli
Authors: Blaukat Andree , Kemme Michael 
Published: November 2022

Abstract:
A gene dosage strategy was developed for efficient production of the C-terminal domain of human mucus proteinase inhibitor (cMPI) in E. coli with polycistronic expression cassettes containing one, two and four tandemly arranged cMPI genes. Upon induction, the synthesis of soluble cMPI increased proportionally to the number of genes integrated due to amplified plasmid copy numbers and enhanced protein stability, reaching a maximum up to 20 mg/I culture. Purified recombinant cMPI retained the inhibitory activity of native MPI.
Current Insights and Molecular Docking Studies of the Drugs under Clinical Trial
as RdRp Inhibitors in COVID-19 Treatment
Authors: Verma Amita , Kumar Pradeep , Pauly Irine , Kumar Singh Ankit , Kumar Adarsh , Singh Yogesh , Thareja Suresh , Kamal Mohammad A. 
Published: November 2022

Abstract:
After the influenza pandemic (1918), COVID-19 was declared a Vth pandemic by the WHO in 2020.
SARS-CoV-2 is an RNA-enveloped single-stranded virus. Based on the structure and life cycle, Protease
(3CLpro), RdRp, ACE2, IL-6, and TMPRSS2 are the major targets for drug development against COVID-19.
Pre-existing several drugs (FDA-approved) are used to inhibit the above targets in different diseases. In coronavirus
treatment, these drugs are also in different clinical trial stages. Remdesivir (RdRp inhibitor) is the only
FDA-approved medicine for coronavirus treatment. In the present study, by using the drug repurposing strategy,
70 preexisting clinical or under clinical trial molecules were used in scrutiny for RdRp inhibitor potent molecules
in coronavirus treatment being surveyed via docking studies. Molecular simulation studies further confirmed
the binding mechanism and stability of the most potent compounds. Docking studies were performed
using the Maestro 12.9 module of Schrodinger software over 70 molecules with RdRp as the target and
remdesivir as the standard drug and further confirmed by simulation studies. The docking studies showed that
many HIV protease inhibitors demonstrated remarkable binding interactions with the target RdRp. Protease inhibitors
such as lopinavir and ritonavir are effective. Along with these, AT-527, ledipasvir, bicalutamide, and
cobicistat showed improved docking scores. RMSD and RMSF were further analyzed for potent ledipasvir and
ritonavir by simulation studies and were identified as potential candidates for corona disease. The drug repurposing
approach provides a new avenue in COVID-19 treatment.

Results:
The docking studies showed that many HIV protease inhibitors demonstrated remarkable binding interactions with the target rdrp. Protease inhibitors such as lopinavir and ritonavir are effective. Along with these, AT-527, ledipasvir, bicalutamide, and cobicistat showed improved docking scores. RMSD and RMSF were further analyzed for potent ledipasvir and ritonavir by simulation studies and were identified as potential candidates for corona disease.
Understanding Learning Styles in Undergraduate Nursing Programs of the Kingdom of Saudi Arabia: An Integrative Literature Review
Authors: Almarwani Abdulaziz Mofdy , Elshatarat Rami 
Published: November 2022

Background:In Saudi Arabia, nursing education is developing fast due to high nursing demand. Alongside this development, nurse educators must identify and understand nursing students learning styles to ensure the multidimensional development of students learning experiences. Students' preferred learning style is an essential element in determining students' unique ways of processing new knowledge, information, and skills.Objective:This literature review aimed to identify the learning styles of undergraduate Saudi nursing students based on the premises of three learning style models: Kolb’s Model, Felder-Silverman Learning, and Visual, Aural, Read/Write, and Kinesthetic (VARK) Learning Styles Inventory.Methods:An integrative review of published studies on Saudi nursing students' learning styles was conducted while adhering to predefined eligibility measures. The research strategy for this study was based on online international databases, such as PubMed, Medline, CINAHL, EBSCO, Google Scholar, and Saudi health databases and journals. The keywords used were: “nursing education,” “learning style,” “learning preference,” “academic learning style,” “undergraduate nursing students,” and “nursing students in Saudi Arabia.”Results:Seven studies met the inclusion criteria. Most of the reviewed literature reported a prominent preference for kinesthetic, accommodating, converging, visual, and active learning styles in nursing students regardless of their age, gender, and level of education in various universities in Saudi Arabia.Conclusion:Students learning styles emphasize the importance of practical experience and students' hands-on practice as the best style that improves nursing students learning experience. The Saudi Arabian education system must adjust to fit students' preferred learning styles and focus on advanced state-of-the-science learning tools in nursing education.
Computer-digital Vision Syndrome Among University Students of Lima City
Authors: Lindo-Cano Elian Fernando , García-Monge Vania Andrea , Castillo-Cadillo Kevin Junior , Sánchez-Tirado Evelyn Andrea , Távara Ingry Marilyn , Morales Juan 
Published: November 2022

Background:
Computer-digital vision syndrome (CVS) is a common occupational disease.

Objective:
This study aims to determine the frequency of CVS and its associated factors in students of a private university located in the north of Lima City.

Methods:
The study was an observational, descriptive, and cross-sectional one. The study variable was CVS, which was assessed using the Computer Vision Syndrome Questionnaire (CVS-Q).

Results:
The analysis was carried out on 709 participants with a mean age of 22.41 years (SD: 4.5; range: 16 to 60). The most frequently used devices were the smartphone and laptop, representing 96.8% (n=686) and 64.7% (n=459), respectively. Of the students exposed to the use of display devices, 58% (n= 413) had CVS. The CVS occurred more frequently in females (p= 0.003), in the 20 to 24-year-old age group (p= 0.022), and in students who were in the first and second academic year (p=0.071). CVS was also found more frequently in lens wearers (p<0.001), in students exposed to screens for 7 to 10 hours and 4 to 6 hours a day (p<0.001), and in students who used two and three electronic devices (p<0.001). CVS occurred mainly in students who used smartphones, and laptops (p<0.05).

Conclusion:
CVS is common among university students. The use of a variety of electronic devices, mainly smartphones and laptops, as well as the exposure time, plays an important role. Therefore, it is recommended to carry out prevention and promotion activities of vision care at the beginning of the academic period.
Communication with diminutives to young children vs. pets in German, Italian, Lithuanian, Russian, and English
Authors: Dressler Wolfgang U. , Mattiello Elisa , Korecky-Kröll Katharina , Noccetti Sabrina , Dabašinskiene Ineta , Kamandulyte-Merfeldiene Laura , Kazakovskaya Victoria V. 
Published: November 2022

This contribution is dedicated to Steven Gillis with whom we have collaborated since the nineties within the “Crosslinguistic Project on Pre- and Protomorphology in Language Acquisition” on both child speech (CS) and child-directed speech (CDS) and also about the development of diminutives (DIMs). We investigate parallels in the use of DIMs and of hypocoristics (HYPs) between CDS and pet-directed speech (PDS), whereas CS is only marginally dealt with. When relevant, also adult-directed speech (ADS), written or oral (especially from electronic corpora, wherever available) will be compared. The presuppositions of this investigation will be stated at the beginning of the Introduction (§ 1). This involves several innovations (beyond descriptions of new data), when compared with existing literature, relevant to theoretical and typological problem areas. We will show that also in DIMs and HYPs used in CDS and PDS semantics only plays a partial or even marginal role when using more DIMs to communicate with young children and young and/or small pets, because it is more relevant that both younger and smaller pets are emotionally closer to us, which is again a pragmatic factor. In regard to language typology, we will apply our concepts of morphological richness and productivity, as argued for and supported in our previous publications, to CDS and PDS and show that richer and more productive patterns of DIM formation of a language also have a typological impact on more frequent and more productive use both in CDS and PDS. We will also apply our concepts of grading morphosemantic transparency/opacity, as argued for and supported in our previous publications, and we start to show, as already shown for CS, that also in CDS towards young children (and similarly in PDS) more morphosemantically transparent DIMs are used than in ADS. This is also connected to their predominantly pragmatic meanings in CDS and PDS (obviously not exclusively pragmatic as in early CS). The languages and authors were selected according to who among the participants in the Crosslinguistic Project on Pre- and Protomorphology in Language Acquisition had CDS and PDS available, plus Elisa Mattiello who has collected English and Italian PDS data.
Quest of Transitioning towards Socialism: Concept Here-so-forth & Course That Nepal Should Command Ahead
Authors: Dahal Atindra 
Published: November 2022

Socialism is one of the key phrases on political landscape across the world, at current time. Among few major buzzwords in global politics of this century, i.e., Nation Building, State Re-structuring, Advanced Democracy, Welfare State, Public Sovereignty, and so on, currently, socialism also has been sufficiently dragging the attention of the politicians, political scientists, scholars and/or researchers in domain of Political/Social Science. All the pro-progressive scholars and politicians urge in adopting socialism orientated advancement in each sector or domain of the society including education, health, economy, governance, judiciary, bureaucracy and so on. But, there is an evident lacuna in exploring the commencement and progress track-record of socialism in terms of both practice and acknowledgement. A clearly comprehensible and communicative blueprint of-long waited and highly touted-socialism prone society is still an absolute missing. Nepal is no longer an exception with the situation of being at this sheer crossroad. Thus, this paper digs out the origin of socialism along with its base concept and gradual development of practice across the world. Further, major features that Nepal ought to embody for pro-socialism transformation as well as political activities and societal reflection prone to socialism will be minutely unearthed here on.
Professores e a manifestação da sexualidade das crianças na escola
Authors: Ferreira Luiza Pinheiro Mendes , Laguárdia de Lima Nadia 
Published: November 2022

Este artigo objetiva apresentar os principais pontos das Conversações realizadas com um grupo de professoras da Educação Infantil para a pesquisa de mestrado intitulada “Psicanálise e educação: respostas encontradas pelos professores diante das manifestações de sexualidade das crianças na escola” e discutir as possibilidades de contribuição da psicanálise para a educação, apontando, principalmente, para as respostas que as professoras encontram diante dos impasses relacionados à sexualidade das crianças. Inicialmente foram pontuadas e selecionadas as falas das professoras. Para fundamentar, buscou-se em literatura de Sigmund Freud, sobre a sexualidade infantil e do caráter traumático que tanto reverbera para a criança, quanto para o adulto. Neste sentido foram apontadas algumas contribuições que a psicanálise pode dar à educação com relação à questão da sexualidade. O propósito foi deslocar o foco do mal-estar das professoras, à possibilidade de mitigar as angústias das docentes em lidar com os impasses da sexualidade infantil. Assim, as reflexões a partir das Conversações, percebeu-se que essa estratégia da Psicologia pode contribuir para que as professoras elaborem novas respostas frente a esse tema nevrálgico.
MITO DE ÉDIPO
Authors: Gimenes Roseli , Santos Jorgina Francisca Severino dos 
Published: November 2022

Os contos de fada provocam leituras que nos remetem a muitos aspectos mitológicos. Este artigo tem como objetivo a leitura do mito de Édipo em relação aos contos de fada na acepção de Bruno Bettelheim (1988) e de Junito de Souza Brandão (1989). A análise que implica nos impasses do mito nos contos de fada segue concepções do imaginário como proposto pelo registro de Jacques Lacan em o Estádio do Espelho (1995). A metodologia qualitativa implica em análise de alguns contos de fada em confronto a temas em que o mito de Édipo aparece. Os resultados apontam que muitos contos de fada constituem leituras semióticas (SANTAELLA, 2001) do mito edipiano seja nas colocações de busca da origem dos personagens, seja na indicação acerca do destino que os rodeia. É possível concluir que a relação entre o mito de Édipo e os contos de fada é constante e revela impasses do destino.
AAlat PengeringAmpas Kelapa (Peneurah)Kontruksi Makna Dalam Ilmu Fisika: Tradisi Orang Aceh
Authors: Maknuni Jauharil , Ayunda Desy Sary 
Published: November 2022

Peunerah merupakan alat tradisional masyarakat Aceh untuk pembuatan ampas kelapa yang akan di keringkan atau dalam bahasa Aceh disebut pliek U (patarana). Peneurah biasanya terbuat dari dua atau tiga batang kayu persegi panjang yang salah satu atau kedua sisinya diberi tekanan, baik dengan memasukkan pasak (alee) pada salah satu sisi ataupun dengan menggunakan ulir. Metode penelitiannya kualitatif, dengan pendekatan studi kasus, dimana peneliti mengkaji keunikanPeneurah yang ada di Aceh. Tujuan dalam penelitian ini untuk mengkajian hubungan Peneurahdalam ilmu fisika. Hasil penelitian menunjukkan bahwa teori fisika yang digunakan peneurah adalah gaya karna ketika penuerah diputar aleenya (pasak) maka harus diberi gaya supaya pliek u tersebut tertekan. Gaya adalah tarikan atau dorongan yang dapat menyebabkan perubahan kecepatan (percepatan) perubahan bentuk benda. tekanan salah satu teori fisika yang digunakan dalam penuerah ketika seseorang memberi gaya dialee penuarah maka pliek u tersebut akan terhimpit dan berubah bentuk. seperti pengertian tekanan yaitu perbandingan antara gaya tekan dengan luas bidang. Ketika kita memutar alee (pasak) penuerah maka alee tersebut akan bergerak melingkar dengan kecepatan yang berbeda-beda dan kelajuan konstan.
Peran Pelatihan Kerja Dalam Meningkatkan Potensi Sumber Daya Manusia Pada Upt-Lk Wilayah I Provinsi Riau Menurut Perspektif Ekonomi Syariah
Authors: Hadi Kamal , Andrini Rozi , Sriyani Sriyani 
Published: November 2022

This paper analyzes the role of job training in increasing the potential of human resources in UPT-LK Region I Riau Province according to a sharia economic perspective and explores the supporting and inhibiting factors in the implementation of job training. This study is essential considering that increasing the potential of human resources is an effort that must be made to compete in the world of work. One of the efforts that can be done to increase human resources' potential is by on-the-job training. This research is field research with qualitative descriptive analysis. The study results indicate that job training has a significant role in increasing the potential of human resources. The trainees stated that they had gained additional knowledge and skills. Factors supporting the implementation of job training at UPT-LK Region I Riau Province, including training materials, instructors, participants' abilities, funding, and strategic locations. While the inhibiting factors are related to facilities and infrastructure, some participants resigned during the training. There is no alumni association of training participants, so that there is no data on graduates who have worked according to the exercise that has been followed. The sharia economic review regarding the role of job training at UPT-LK Region I Riau Province, in general, is by sharia principles, namely kafa'ah, himmatul-Amal, and Amanah. Keywords: Role, Job Training, HR