bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prenatal exposure to trans fatty acids and head growth in fetal life and childhood: triangulating confounder-adjustment and instrumental variable approaches
Authors: Zou Runyu , Labrecque Jeremy A. , Swanson Sonja A. , Steegers Eric A. P. , White Tonya , El Marroun Hanan , Tiemeier Henning 
Published: September 2022

AbstractDietary trans fatty acids (TFAs) are primarily industrially produced and remain abundant in processed food, particularly in low- and middle-income countries. Although TFAs are a cause of adverse cardiometabolic outcomes, little is known about exposure to TFAs in relation to brain development. We aimed to investigate the effect of maternal TFA concentration during pregnancy on offspring head growth in utero and during childhood. In a prospective population-based study in Rotterdam, the Netherlands, with 6900 mother–child dyads, maternal plasma TFA concentration was assessed using gas chromatography in mid-gestation. Offspring head circumference (HC) was measured in the second and third trimesters using ultrasonography; childhood brain morphology was assessed using magnetic resonance imaging at age 10 years. We performed regression analyses adjusting for sociodemographic and lifestyle confounders and instrumental variable (IV) analyses. Our IV analysis leveraged a national policy change that led to a substantial reduction in TFA and occurred mid-recruitment. After adjusting for covariates, maternal TFA concentration during pregnancy was inversely related to fetal HC in the third trimester (mean difference per 1% wt:wt increase: − 0.33, 95% CI − 0.51, − 0.15, cm) and to fetal HC growth from the second to the third trimester (− 0.04, 95% CI − 0.06, − 0.02, cm/week). Consistent findings were obtained with IV analyses, strengthening a causal interpretation. Association between prenatal TFA exposure and HC in the second trimester or global brain volume at age 10 years was inconclusive. Our findings are of important public health relevance as TFA levels in food remain high in many countries.
Achromatic Quarter-Waveplate for the Terahertz Frequency Range Made by 3D Printing
Authors: Jäckel Alexander , Ulm David , Kleine-Ostmann Thomas , Castro-Camus Enrique , Koch Martin , Ornik Jan 
Published: September 2022

AbstractHere we propose a 3D printed form-birefringent achromatic quarter-waveplate targeting the lower terahertz frequency range. The monolithically fabricated waveplate consists of three individual layers of different thickness and orientation of the stratified structure resulting in the achromatic response. The experimental results show that the performance of the fabricated waveplate fits the optimal behaviour within 5 % in terms of ellipticity and phase shift for frequencies between 75 GHz and 110 GHz.
Focal dissection and rupture of left atherosclerotic subclavian artery: a rare cause of haemothorax
Authors: Tse Rexson , Thompson Melissa , Han Issac , Olumbe Alex 
Published: September 2022

AbstractWe report a rare case of a focally dissected and ruptured atherosclerotic left subclavian artery leading to haemothorax. A man in his 50 s who suffered from hypertension and gout was found dead in bed unexpectedly. Postmortem examination showed a focally dissected and ruptured atherosclerotic left subclavian artery with relatively disease-free aorta and major branches. Although theoretically possible, focal atherosclerosis of left subclavian artery compounded by hypertension causing focal dissection and rupture is not previously reported in literature.
Optimizing monitoring of an endemic terrestrial salamander (Speleomantes ambrosii): comparing cost-effectiveness of different methods for abundance estimation
Authors: Rosa Giacomo 
Published: September 2022

AbstractIn order to correctly plan conservation and management of animal populations, it is fundamental to obtain reliable information on population abundance using cost-effective monitoring methods. In the case of small terrestrial vertebrates, capture–mark–recapture, removal sampling and counts of unmarked individuals have proven to be reliable techniques to estimate population abundance. In the present study, we applied a multinomial N-mixture modelling approach, performed through a double-observer sampling protocol, to estimate population size of the endemic terrestrial salamander Speleomantes ambrosii. We aimed at comparing cost-effectiveness of this protocol with those of other estimation methods (i.e., capture–mark–recapture and removal sampling), with particular attention to management and monitoring guidelines. The double-observer multinomial N-mixture protocol was the most cost-effective among the different methods: given its ease of application and cost-effectiveness, we encourage its employment for long-term monitoring and conservation plans of the near-threatened plethodontid salamander Speleomantes ambrosii.
Sustained inhibition of CC-chemokine receptor-2 via intraarticular deposition of polymeric microplates in post-traumatic osteoarthritis
Authors: Ozkan Huseyin , Di Francesco Martina , Willcockson Helen , Valdés-Fernández José , Di Francesco Valentina , Granero-Moltó Froilán , Prósper Felipe , Decuzzi Paolo , Longobardi Lara 
Published: September 2022

AbstractPosttraumatic osteoarthritis (PTOA) is mostly treated via corticosteroid administration, and total joint arthroplasty continues to be the sole effective intervention in severe conditions. To assess the therapeutic potential of CCR2 targeting in PTOA, we used biodegradable microplates (µPLs) to achieve a slow and sustained intraarticular release of the CCR2 inhibitor RS504393 into injured knees and followed joint damage during disease progression. RS504393-loaded µPLs (RS-µPLs) were fabricated via a template-replica molding technique. A mixture of poly(lactic-co-glycolic acid) (PLGA) and RS504393 was deposited into 20 × 10 μm (length × height) wells in a polyvinyl alcohol (PVA) square-patterned template. After physicochemical and toxicological characterizations, the RS504393 release profile from µPL was assessed in PBS buffer. C57BL/6 J male mice were subjected to destabilization of the medial meniscus (DMM)/sham surgery, and RS-µPLs (1 mg/kg) were administered intraarticularly 1 week postsurgery. Administrations were repeated at 4 and 7 weeks post-DMM. Drug free-µPLs (DF-µPLs) and saline injections were performed as controls. Mice were euthanized at 4 and 10 weeks post-DMM, corresponding to the early and severe PTOA stages, respectively. Knees were evaluated for cartilage structure score (ACS, H&E), matrix loss (safranin O score), osteophyte formation and maturation from cartilage to bone (cartilage quantification), and subchondral plate thickness. The RS-µPL architecture ensured the sustained release of CCR2 inhibitors over several weeks, with ~ 20% of RS504393 still available at 21 days. This prolonged release improved cartilage structure and reduced bone damage and synovial hyperplasia at both PTOA stages. Extracellular matrix loss was also attenuated, although with less efficacy. The results indicate that local sustained delivery is needed to optimize CCR2-targeted therapies.
Graphical abstract
Computation of Artificial Meteors Trajectory and Ablation
Authors: Raposo-Pulido V. , Lemal A. , Urrutxua H. , Peláez J. , Kimura N. , Sahara H. , Kamachi K. , Okajima L. 
Published: September 2022

AbstractThis work has been motivated by the lack of meteor data, which hinders the determination of the mass and composition of natural meteors. To advance the knowledge of meteors science, the Japanese start-up ALE Co. Ltd. (standing for Astro Live Experiences) designed hundreds of 1-cm diameter particles composed of materials representative of natural meteors, which will be release at an altitude of 300 km by an original payload in 2023. During entry, the light emitted by the particles will be analyzed by spectrometers and cameras on the ground to characterize the thermal and optical properties of the materials. This paper carries out a sensitivity analysis and aims to discuss the modeling parameters predicting full disintegration of the particles before touching ground. This paper presents the efforts undertaken to compute the trajectory of artificial meteors during their entry into Earth’s atmosphere. Various materials representative of natural meteors and their thermal response were modeled. The trajectory of artificial meteors was computed by solving the equation of motion including mass conservation. The influence of the drag coefficient, heat transfer coefficient, and geometric parameters was evaluated through the statistical analysis of Grid Sampling and Monte Carlo simulations. They were shown to have a sizeable effect on the trajectory, mass loss, latitude and altitude of demise. The computations demonstrate full demisability of the artificial meteor above 60 km, which is compliant with international safety regulations.
Fully Safe Rendezvous Strategy in Cis-Lunar Space: Passive and Active Collision Avoidance
Authors: Bucchioni Giordana , De Benedetti Matteo , D’Onofrio Fabio , Innocenti Mario 
Published: September 2022

AbstractThe future assembly of the Lunar Orbital Platform Gateway, on a near 9:2 resonant Rectilinear Halo Orbit, requires the necessity of designing safe and reliable strategies to perform rendezvous and docking with the station. The paper describes and tests a strategy to guarantee the safety of an entire rendezvous manoeuvre in the proximity of the Moon L2 Lagrangian point with respect to a specific set of failures. The safety in the far range is guaranteed through the automatic allocation of selected hold-points, whereas during close range rendezvous the safety is actively guaranteed in the presence of selected failures. The main goal of the paper is to contribute to the very limited literature about autonomous design of the guidance for rendezvous in presence of a non negligible third body influence, where safety considerations are paramount. The proposed approach is based on the exploitation of the manifold theory used in the circular restricted three body problem model to guarantee the passive safety in the far-range section, and on an optimal and reliable active collision avoidance manoeuvre to guarantee the safety for the close range approach.
Reviewing the Origins of You: How Childhood Shapes Later Life (2020)
Authors: Petillo Laura 
Published: September 2022

AbstractThe Origins of You; How Childhood Shapes Later Life (2020) explores the results of the Dunedin Multidisciplinary Health and Development Study, a longitudinal look at 1,000 participants since 1970. This review examines the works’ significant correlations between health and delinquency in adulthood based on childhood experiences, neighborhoods, family dynamics, and genetic predispositions. The Dunedin Study discoveries regarding childhood personality disorders, ADHD, bullying, puberty, and parenting styles offer bold statements that challenge generally accepted ideas. With over 1,200 publications on the findings of the Dunedin Study—several appearing in peer-reviewed journals—this book accomplishes in its purpose what many others have not: sharing the study’s results in a way that is meaningful and enjoyable in a reference-book format. This book review discusses why The Origins of You (2020) is a great resource for parents, educational professionals, teachers, and school administrators.
Relationship between education and well-being in China
Authors: Liu Sijia , Heshmati Almas 
Published: September 2022

AbstractWell-being is often quantitatively measured based on individuals’ income or health situation but the relationship between education and well-being has not been fully investigated. It is also important to compare well-being using different individual characteristics especially gender. This paper analyzes well-being using a unique dataset from the Chinese General Social Surveys in 2012, 2013, and 2015. Two measures of well-being are used: self-assessed unidimensional subjective well-being and parametrically estimated multidimensional objective well-being. Objective well-being is a composite parametric index with contributions from different domains of education influenced by identity, capability, and material well-being. These help in understanding the differences between and compare subjective and objective well-being. The results of our descriptive and regression analysis suggests that the multidimensional well-being index differs from subjective well-being in ranking individuals grouped by important common characteristics. These differences are captured by our study which helps to broaden the measurement and analysis of the multidimensionality of the well-being index. Education influences well-being positively, conditional on controlling for identity, capability, material and marital status, and Confucianism. Investments in education and female empowerment which target well-being measures will help reduce the dimensionality of the gender gap in rural China, in particular those attributed to Confucianism.
For Our World Without Sound: the Opportunistic Debitage in the Italian Context—a Methodological Evaluation of the Lithic Assemblages of Pirro Nord, Cà Belvedere di Montepoggiolo, Ciota Ciara Cave and Riparo Tagliente
Authors: Carpentieri Marco , Arzarello Marta 
Published: September 2022

AbstractThe informative potential taken on by lithic artefacts has increased over the years. They gradually grew into proxies to detect the most relevant features of human material culture, including cognitive abilities to realise stone tools or, in other words, to track down the delineation of behavioural complexity. Consequently, notions like predetermination, standardisation (morphologically likewise) and hierarchisation have been intensely used in lithic technology as markers of such complexity, leading to ruling out contexts lacking any trace of these traits. Within the present state of the art, the use of the terms expedient and opportunism has characterised, in a negative way, the dichotomy between complex and simple within prehistoric contexts. Even if a requalification of expedient technologies has been recently observed, opportunistic behaviours still connote the complete absence of planning and complexity (even in terms of the mental scheme) within lithic industries. This background often prevented a consideration as relevant, from a technological and methodological perspective, these assemblages, primarily when Lower Palaeolithic contexts were addressed. With the definition and use of the term opportunistic debitage, this work questions the possible methodological implications of assemblages known as complexity- and planning-free and that can be found throughout different chronological and cultural phases.
Ingredients for Responsible Machine Learning: A Commented Review of The Hitchhiker’s Guide to Responsible Machine Learning
Authors: Marmolejo-Ramos Fernando , Ospina Raydonal , García-Ceja Enrique , Correa Juan C. 
Published: September 2022

AbstractInThe hitchhiker’s guide to responsible machine learning, Biecek, Kozak, and Zawada (here BKZ) provide an illustrated and engaging step-by-step guide on how to perform a machine learning (ML) analysis such that the algorithms, the software, and the entire process is interpretable and transparent for both the data scientist and the end user. This review summarises BKZ’s book and elaborates on three elements key to ML analyses: inductive inference, causality, and interpretability.
Lichen Sclerosus and Sexual Dysfunction: A Systematic Review and Meta-Analysis
Authors: Pope Rachel , Lee Min Ho , Myers Anna , Song Junmin , Abou Ghayda Ramy , Kim Jong Yeob , Hong Sung Hwi , Lee Se Bee , Koyanagi Ai , Jacob Louis , Smith Lee , Shin Jae Il 
Published: September 2022

AbstractBackgroundLichen sclerosus (LS) is a common autoimmune dermatological condition that is often under-diagnosed in women and has been documented to affect quality of life and sexual function.AimTo determine the prevalence of sexual dysfunction among women with vulvar lichen sclerosus.MethodsThe authors conducted a systematic review and meta-analysis of the existing research on LS and sexual function in database including PubMed using search terms: lichen sclerosus OR vulvar lichen sclerosus OR vulvar lichen sclerosus et atrophicus OR kraurosis vulvae) AND (sexual function OR sexual functions OR sexual disorder OR sexual disorders OR sexual activity OR sexual activities OR sexual dysfunction OR sexual dysfunctions OR dyspareunia OR vaginismus).OutcomesNearly 60% of women with lichen sclerosus suffer from sexual dysfunction.ResultsTwo hundred and ten studies were initially identified. Twenty-six articles met inclusion criteria and 3 were excluded as they did not relate to sexual function, were regarding a surgical or medical intervention and sexual dysfunction and one was a review article. Therefore, 23 studies were included in the final analysis resulting in a cumulative 486 participants with LS with 208 patients experiencing any kind of sexual dysfunction. Meta-analysis presented prevalence of sexual dysfunction among LS patients as 59% (95% CI: 48 – 70%). Dyspareunia or generalized pain with intercourse was the most commonly reported type of dysfunction.Clinical ImplicationsDiscussing sexual concerns with women with LS could empower them to seek treatment.Strengths and LimitationsFew articles met criteria for inclusion.ConclusionA large proportion of women with LS experience sexual dysfunction. More research is needed, especially that which includes biopsy-proven LS and validated tools on sexual function.
Joint and Several Liability in EU Competition Law
Authors: Sadrak Katarzyna 
Published: September 2022

Contribution claims in antitrust are controversial and under-researched in the legal literature. This book provides the first comprehensive analysis of contribution claims in EU competition law. By drawing on the historical and current practice of EU and national courts, as well as national laws of major EU jurisdictions, it explains contribution claims in antitrust law in concrete and practical terms. It also provides much needed clarity on the relationship between competition law and joint and several liability, as well as guiding those concerned by contribution claims through the issues that are likely to arise. Topics examined include the requirements competition law sets for contribution claims; the criteria for dividing antitrust liability between individual co-infringers; the impact of EU Directive 2014/10; and whether liability sharing agreements can resolve the problems joint and several liability brings to EU competition law.
Wave power extraction from a floating elastic disk-shaped wave energy converter
Authors: Zheng Siming , Michele Simone , Liang Hui , Meylan Michael H. , Greaves Deborah 
Published: September 2022

In this paper, a concept of a floating elastic wave energy converter consisting of a disk-shaped elastic plate is proposed. The floating plate is moored to the seabed through a series of power take-off (PTO) units. A theoretical model based on the linear potential flow theory and eigenfunction matching method is developed to study the hydroelastic characteristics and evaluate wave power absorption of the device. The PTO system is simulated as a discrete PTO, and moreover, it is also modelled as a continuum PTO to represent the case when the PTO system is composed of a large number of PTO units. The continuum PTO approximation is tested against the discrete PTO simulation for accuracy. Two methods are proposed to predict the wave power absorption of the device. After running convergence analysis and model validation, the present model is employed to do a multiparameter impact analysis. The device adopting a continuum PTO system is found to capture wave power efficiently in an extensive range of wave frequencies. For the continuum PTO system, it is theoretically possible to adopt optimised PTO damper and stiffness/mass to guarantee the absorption of 100 % of the energy flux available in one circular component of the plane incident wave.
Racial and ethnic differences in suicidal behavior and mental health service use among US adults, 2009–2020
Authors: Bommersbach Tanner J. , Rosenheck Robert A. , Rhee Taeho Greg 
Published: September 2022

AbstractBackgroundWhile suicide rates have recently declined for White individuals, rates among Black and Hispanic individuals have increased. Yet, little is known about racial/ethnic differences in precursors to suicide, including suicidal ideation (SI) and suicide attempts (SA).MethodsData from 2009–2020 National Survey of Drug Use and Health (NSDUH) consisted of non-institutionalized US civilians aged ⩾18 (n= 426 008). We compared proportions of White, Black, and Hispanics among adults reporting no past-year suicidal thoughts/behavior, SI, and SA. Multivariable-adjusted analyses were used to evaluate the independence of observed racial/ethnic differences in past-year SI, SA, and mental health service use.ResultsIn the entire sample, 20 791 (4.9%) reported past-year SI only and 3661 (0.9%) reported a SA. Compared to White individuals, Black and Hispanic individuals were significantly less likely to report past-year SI [OR 0.73 (95% CI 0.69–0.77); OR 0.75 (95% CI 0.71–0.79), respectively], but more likely to report a past-year SA [OR 1.45 (95% CI 1.28–1.64); OR 1.19 (95% CI 1.04–1.37), respectively] even after multivariable adjustment. Black and Hispanic individuals were significantly less likely to use mental health services, but the lack of significant interactions between race/ethnicity and SI/SA in association with service use suggests differences in service use do not account for differences in SI or SA.ConclusionsBlack and Hispanic individuals are significantly less likely than White individuals to report SI but more likely to report SAs, suggesting differences in suicidal behavior across race/ethnicity that may be impacted by socio-culturally acceptable expressions of distress and structural racism in the healthcare system.