bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantitative Surface Quality Assessment of Car Outer Panels with a Virtual Light Room
Authors: Guillon Frédéric , Camanho Arthur , Padovani Renan , Gripp Jorge , Sakuramoto Carlos 
Published: May 2022

Abstract
Perception is reality. A customers’ perception about the quality of a car is closely linked to the aspect of its outer panels and that reality translates into what motivates customers to choose one car over another. The smoothness of the panels, how much gap is visible and how that looks; these visual cues are considerations within a customer’s decision-making process. The process of choosing a new car is certainly subjective and varies from customer to customer, but Original Equipment Manufacturers (OEMs) agree that the visual appeal of the body of a car is a key factor. Building a car only to find surface imperfections results in huge costs in postproduction rectifying those perceived defects. The further into production these defects are found the more expensive it is to fix them. Some OEMs release cars into the buying cycle knowing that their engineering teams are still struggling to fix surface defects. There is a solution to this though. Numerical simulation. This action can and should be used to find surface defects very early in the design process. Surface quality assessment via numerical simulation is achieved by analysing different contours that relate stress or strain values. Other subjective criteria exist, but it is often very difficult to ascertain if a surface defect is severe enough to be detected by human eye. This paper describes a simulation methodology that, when used along with a software that reads surface light distortions and rates them, will give reliable results allowing engineers to fix problems before a car is built. This technology was developed using actual data supplied by a partnering OEM. Current examples will be presented, comparing parts “as designed” with parts “as manufactured”. After manufacturing parts will show variations caused by the stamping process such as skid marks, bumps, hollows, etc. All that can be accurately predicted by simulation.
Design of a simple shear test for large strains with sequential re-machining of the specimen edges
Authors: Colon Xavier , Adlafi Morwan , Galpin Bertrand , Maheo Laurent , Grolleau Vincent 
Published: May 2022

Abstract
The simple shear test is a standard experiment used for the calibration of plasticity models. For thin sheets, the specimen can be as simple as a rectangular strip, or feature optimized geometries of the free edges. These enhancements are mainly motivated by the undesirable initiation of fracture from the free edges, which limit the usable strain range of the test. Previous studies have shown that fracture from the edges occurs due to a local stress state close to uniaxial tension in these areas. In an attempt to increase the maximum strain, a sequential simple shear test is proposed. The specimen is a sheet metal strip with two opposing cut-outs with rounded concave edges. The specimen is mounted in a shear testing device, composed of two jaws with a prismatic joint connection. The shear test protocol includes multiple two-steps sequences. First, an interrupted shear test is performed up to a given value of displacement. Second, the shear testing device, along with the clamped specimen, is positioned in a milling machine and the rounded free edges of the specimen are re-machined. The application of the proposed testing protocol is presented for three engineering materials. It is found that the valid range of this experiment (i.e. the maximum strains attained before specimen failure) can be substantially extended through repeated re-machining of the specimen boundaries.
Simulations of plastic deformation by anisotropic hardening yield functions for QP1180
Authors: Chen Zhe , Lou Yanshan 
Published: May 2022

Abstract
This research compares the accuracy, computation efficiency and user-friendliness of the Hill48 and three anisotropic hardening models (S-Y 2009, CQN and newly proposed one) for QP1180 steel sheet. Experiments are conducted with dogbone and notched specimens along RD, DD and TD and bulging specimens for strain hardening behavior under equibiaxial tension. These models are calibrated by the experimental data above. The calibrated models are applied to simulate the uniaxial tension and plane strain tension tests for the metal. The simulation time and accuracy of the models are compared for both uniaxial tension and plane strain tension tests to evaluate their accuracy and computation efficiency. The results suggest that the CQN and proposed models are the most accurate among the four models compared, but the computation efficiency of the proposed model can dramatically reduce the numerical simulation time by 20%~40% compared to the CQN model. The comparison shows that the proposed model is the most accurate and is higher in numerical computation efficiency for engineers. Therefore, the proposed model is recommended to be utilized to describe anisotropic hardening behaviors during sheet metal forming processes.
Environment-friendly and biodegradable a-Fe2O3/C20H38O11nanocomposite growth to lengthen the Solanum lycopersicum storage process
Authors: Guleria Geetika , Thakur Sapna , Sharma Dhananjay K , Thakur Shweta , Kumari Poonam , Shandilya Mamta 
Published: May 2022

Abstract
In this work, the growth of enviro-friendly and biodegradable α-Fe2O3/C20H38O11 nanocomposite is reported by means of a real time application to prolong the storage life of Tomato (Solanum Lycopersicum). A low temperature technique is used to prepare the α-Fe2O3 nanoparticles to obtain a crystalline nanopowder. XRD confirms the phase formation and crystalline nature of α-Fe2O3 nanoparticles. The surface morphology and elemental analysis of α-Fe2O3/C20H38O11 nanocomposite is conducted by SEM and EDX. Nanocomposite exhibits excellent antimicrobial activity against Klebsiella pneumoniae and Staphylococcus aureus bacteria. Tomato fruit samples are coated with two different concentrations of α-Fe2O3/C20H38O11 nanocomposite with 5% UC1A, UC2A and 3% UC1B, UC2B; and uncoated samples UC1, UC2 are stored at room temperature (25 ± 2 °C) and refrigerator temperature (4 °C) respectively for ascorbic acid (vitamin C) analysis on days 0, 4, 8, 12 and 16. Our study revealed that a 3% concentration of α-Fe2O3/C20H38O11 nanocomposite material is quite potent in maintaining quality aspects of the tomato fruit with no decline in vitamin C under refrigerated conditions up to the 16th day. FTIR analysis of all samples was done to determine the functional groups present in tomato samples after storage. Atomic absorption spectrometer (AAS) was used to analyse the content of Fe in tomato samples.
Facts and Propositions, Trueman-Style
Authors: Sullivan Peter 
Published: May 2022

AbstractIn a recent book, Robert Trueman develops a version of the identity theory of truth, the theory that true propositions are not in some kind of correspondence with, but are rather identical with, facts. He claims that this theory ‘collapses the gap between mind and world’. Whether it does so will obviously depend on how the theory is to be understood, which in turn depends on the argumentative route to it. Trueman’s route is clear, rigorous, and free of extravagant assumptions. Perhaps because of those merits it seems obvious that it falls short of the claim he makes for it. But there are difficult questions about the nature of the shortfall and about what in the character of Trueman’s philosophical approach prevents him from appreciating it. The paper explores those questions through a comparison with Moore’s ‘original’ identity theory and the Idealist philosophy he directed it against.
Globally Accessible Distributed Data Sharing (GADDS): a decentralized FAIR platform to facilitate data sharing in the life sciences
Authors: Vazquez Pavel , Hirayama-Shoji Kayoko , Novik Steffen , Krauss Stefan , Rayner Simon 
Published: May 2022

AbstractMotivationTechnical advances have revolutionized the life sciences and researchers commonly face challenges associated with handling large amounts of heterogeneous digital data. The Findable, Accessible, Interoperable and Reusable (FAIR) principles provide a framework to support effective data management. However, implementing this framework is beyond the means of most researchers in terms of resources and expertise, requiring awareness of metadata, policies, community agreements and other factors such as vocabularies and ontologies.ResultsWe have developed the Globally Accessible Distributed Data Sharing (GADDS) platform to facilitate FAIR-like data-sharing in cross-disciplinary research collaborations. The platform consists of (i) a blockchain-based metadata quality control system, (ii) a private cloud-like storage system and (iii) a version control system. GADDS is built with containerized technologies, providing minimal hardware standards and easing scalability, and offers decentralized trust via transparency of metadata, facilitating data exchange and collaboration. As a use case, we provide an example implementation in engineered living material technology within the Hybrid Technology Hub at the University of Oslo.Availability and implementationDemo version available at https://github.com/pavelvazquez/GADDS.Supplementary informationSupplementary data are available at Bioinformatics online.
Metapone: a Bioconductor package for joint pathway testing for untargeted metabolomics data
Authors: Tian Leqi , Li Zhenjiang , Ma Guoxuan , Zhang Xiaoyue , Tang Ziyin , Wang Siheng , Kang Jian , Liang Donghai , Yu Tianwei 
Published: May 2022

AbstractMotivationTesting for pathway enrichment is an important aspect in the analysis of untargeted metabolomics data. Due to the unique characteristics of untargeted metabolomics data, some key issues have not been fully addressed in existing pathway testing algorithms: (i) matching uncertainty between data features and metabolites; (ii) lacking of method to analyze positive mode and negative mode liquid chromatography–mass spectrometry (LC/MS) data simultaneously on the same set of subjects; (iii) the incompleteness of pathways in individual software packages.ResultsWe developed an innovative R/Bioconductor package: metabolic pathway testing with positive and negative mode data (metapone), which can perform two novel statistical tests that take matching uncertainty into consideration—(i) a weighted gene set enrichment analysis-type test and (ii) a permutation-based weighted hypergeometric test. The package is capable of combining positive- and negative-ion mode results in a single testing scheme. For comprehensiveness, the built-in pathways were manually curated from three sources: Kyoto Encyclopedia of Genes and Genomes, Mummichog and The Small Molecule Pathway Database.Availability and implementationThe package is available at https://bioconductor.org/packages/devel/bioc/html/metapone.html.Supplementary informationSupplementary data are available at Bioinformatics online.
Characteristics of emergency general surgery services in Switzerland: A nationwide survey
Authors: Quaile O , Perrodin S , Trippel A , Schnüriger B ,   Swiss ACS
Published: May 2022

Abstract

Objective
Running emergency general surgery (EGS) services is challenging and requires significant personnel and institutional resources. In addition, increasing specialization of surgeons has made the provision of EGS services more problematic. The aim of this study was to elaborate a nationwide overview of the individual hospital organization systems of EGS services in Switzerland and to find related challenges and difficulties.

Methods
Telephone based standardized survey of all Swiss hospitals with a state medical treatment contract of the Swiss Federal Office of Public Health (FOPH) including a surgical and emergency unit (ER). The telephone interviews were conducted between December 2021 and January 2022. A corresponding junior, senior consultant or attending surgeon was interviewed per hospital by one of four interviewers. Descriptive and univariate analysis was performed using SPSS Version 28.

Results
A total of 72 of 79 (91.1%) surgical clinics participated in the telephone survey. There were 19 (26.4%) hospitals with &lt;100 beds, 37 (54.2%) hospitals with 100–300 beds, 7 (9.7%) with 300–600 beds, and 7 (9–7%) with &gt;600 beds. 57 (79.2%) hospitals have both, an ER and an intensive care unit (ICU). Eight (11.1%) hospitals have solely an intermediate care unit (IMC), 7 (9.7%) solely an ER. The average number of surgeons per hospital was proportional to the size of the hospital: 11.1±4.1 surgeons in hospitals &lt;100 beds, 23.1±8.8 surgeons in hospitals with 100–300 beds, 29.1±10 surgeons in hospitals with 300–600 beds, and 37.7±9.4 surgeons in hospitals &gt;600 beds. The percentage of surgical staff on EGS service per hospital was significantly higher in smaller hospitals (&lt;100 beds), however, with a smaller number of surgeons on service per day. Regarding personal resources to run the EGS services, for hospitals with &gt;300 beds similar person-days per month were found (159.7±24.7).

Conclusion
This study elaborates and characterises for the first time EGS services in Switzerland. Different EGS systems are in place and are related to the size of the hospitals. The individual EGS systems have been discussed regarding (1) surgical expertise, (2) continuity of treating surgical teams, (3) teaching and (4) optimization of personnel hospital resources. Moreover, based on these results, recommendations have been made to optimize EGS services.
Construction and Validation of Social Work Intervention Complexity Scale in Hospital Care Settings
Authors: Carvalho Helena , Espírito Santo Maria Inês , Ferreira Jorge 
Published: May 2022

Abstract
The aim of this article was to develop and validate a scale to measure the complexity of social intervention with adults in hospital care settings. Two separate studies were conducted (N1 = 224 and N2 = 224). Study 1 was focused on the development of the Social Work Intervention Complexity (SWIC) scale and on its dimensionality. The exploratory factorial analysis was conducted to identify its factor structure, and reliability was assessed. Study 2 examined the construct validity of the scale and tested its robustness in the two samples with an invariance test. Single-group and multi-group confirmatory factor analyses were used. The results confirmed a three-factor structure and convergent validity, and discriminant validity was guaranteed. The invariance of the measuring instrument across the two groups was also proved. The practical implications arising from the validation of the SWIC scale are also a distinctive feature of this work. The application can be implemented to monitor the complexity of social intervention with adults in hospital care settings. In the future, different hospitals could integrate the application of the SWIC scale into their protocol since the social worker's professional practice must be combined with scientific rigor and the quality of social intervention.
Circulating biomarkers for management of cancer therapeutics-related cardiac dysfunction
Authors: Tonry Claire , Russell-Hallinan Adam , McCune Claire , Collier Patrick , Harbinson Mark , Dixon Lana , Watson Chris J 
Published: May 2022

AbstractCancer therapeutics-related cardiac dysfunction (CTRCD) has emerged as a major cause of morbidity and mortality in cancer survivors. Effective clinical management of CTRCD is impeded by a lack of sensitive diagnostic and prognostic strategies. Circulating molecular markers could potentially address this need as they are often indicative of cardiac stress before cardiac damage can be detected clinically. A growing understanding of the underlying physiological mechanisms for CTRCD has inspired research efforts to identify novel pathophysiologically relevant biomarkers that may also guide development of cardio-protective therapeutic approaches. The purpose of this review is to evaluate current circulating biomarkers of cardiac stress and their potential role in diagnosis and management of CTRCD. We also discuss some emerging avenues for CTRCD-focused biomarker investigations.
Incidence, predictors and prognostic value of permanent pacemaker implantation following sutureless valve implantation in low-risk aortic stenosis patients
Authors: Vilalta Victoria , Cediel Germán , Mohammadi Siamak , López Helena , Kalavrouziotis Dimitri , Resta Helena , Dumont Eric , Voisine Pierre , Philippon François , Escabia Claudia , Borrellas Andrea , Alperi Alberto , Bayes-Genis Antoni , Rodes-Cabau Josep 
Published: May 2022

Abstract

OBJECTIVES
Sutureless aortic valve replacement (SU-SAVR) has been associated with higher rates of permanent pacemaker (PPM) compared with conventionally implanted aortic bioprostheses. The purpose of this study was to determine the incidence, predictors and mid-term prognostic impact of PPM after Perceval (Livanova, London, UK) SU-SAVR in low-risk patients.

METHODS
A total of 400 consecutive low-risk (EuroSCORE II &lt; 4%) patients without prior pacemaker who underwent surgical aortic valve replacement with the Perceval prosthesis from 2013 to 2019 in 2 centres were included. Baseline, clinical and electrocardiographic parameters, procedural characteristics and follow-up data were collected.

RESULTS
PPM was required in 36 (9%) patients after SU-SAVR, with a median time between the procedure and PPM implantation of 7.5 (4.5–10.5) days. Older age and prior right bundle branch block (RBBB) were associated with an increased risk of PPM (P &lt; 0.05 for all), but only baseline RBBB was found to be an independent predictor of new PPM requirement (odds ratio: 2.60, 95% confidence interval: 1.15–5.81; P = 0.022). At a median follow-up of 3.4 (2.3–4.5) years, there were no differences between groups in mortality (PPM: 36%, no PPM: 22%, P = 0.105) or heart failure rehospitalization (PPM: 25%, no PPM: 21%, P = 0.839).

CONCLUSIONS
About 1 out of 10 low-risk patients with aortic stenosis undergoing SU-SAVR with the Perceval prosthesis required PPM implantation. Prior RBBB determined an increased risk (close to 3-fold) of PPM following the procedure. PPM was not associated with a higher risk of clinical events at 3-year follow-up.
Closed-chest unilateral thoracoscopic ablation: box lesion with radiofrequency clamps only
Authors: Vos Lara M , Fleerakkers Jelle , Hofman Frederik N , van Putte Bart P 
Published: May 2022

Abstract
In this article, we describe the modified technique of a unilateral closed-chest thoracoscopic ablation and left atrial appendage closure including a box lesion that is made by radiofrequency clamps only for the treatment of atrial fibrillation. By abandoning the unidirectional pen devices and replacing these by radiofrequency clamps, we aim to further improve the procedural efficacy and shorten operation time while minimizing surgical exposure for the patient.
Cardiopulmonary exercise testing and efficacy of percutaneous coronary intervention: a substudy of the ORBITA trial
Authors: Ganesananthan Sashiananthan , Rajkumar Christopher A , Foley Michael , Thompson David , Nowbar Alexandra N , Seligman Henry , Petraco Ricardo , Sen Sayan , Nijjer Sukhjinder , Thom Simon A , Wensel Roland , Davies John , Francis Darrel , Shun-Shin Matthew , Howard James , Al-Lamee Rasha 
Published: May 2022

Abstract

Aims
Oxygen-pulse morphology and gas exchange analysis measured during cardiopulmonary exercise testing (CPET) has been associated with myocardial ischaemia. The aim of this analysis was to examine the relationship between CPET parameters, myocardial ischaemia and anginal symptoms in patients with chronic coronary syndrome and to determine the ability of these parameters to predict the placebo-controlled response to percutaneous coronary intervention (PCI).

Methods and results
Patients with severe single-vessel coronary artery disease (CAD) were randomized 1:1 to PCI or placebo in the ORBITA trial. Subjects underwent pre-randomization treadmill CPET, dobutamine stress echocardiography (DSE) and symptom assessment. These assessments were repeated at the end of a 6-week blinded follow-up period.
A total of 195 patients with CPET data were randomized (102 PCI, 93 placebo). Patients in whom an oxygen-pulse plateau was observed during CPET had higher (more ischaemic) DSE score [+0.82 segments; 95% confidence interval (CI): 0.40 to 1.25, P = 0.0068] and lower fractional flow reserve (−0.07; 95% CI: −0.12 to −0.02, P = 0.011) compared with those without. At lower (more abnormal) oxygen-pulse slopes, there was a larger improvement of the placebo-controlled effect of PCI on DSE score [oxygen-pulse plateau presence (Pinteraction = 0.026) and oxygen-pulse gradient (Pinteraction = 0.023)] and Seattle angina physical-limitation score [oxygen-pulse plateau presence (Pinteraction = 0.037)]. Impaired peak VO2, VE/VCO2 slope, peak oxygen-pulse, and oxygen uptake efficacy slope was significantly associated with higher symptom burden but did not relate to severity of ischaemia or predict response to PCI.

Conclusion
Although selected CPET parameters relate to severity of angina symptoms and quality of life, only an oxygen-pulse plateau detects the severity of myocardial ischaemia and predicts the placebo-controlled efficacy of PCI in patients with single-vessel CAD.
Interventions aimed at improving healthcare and health education equity for adult d/Deaf patients: a systematic review
Authors: Morisod Kevin , Malebranche Mary , Marti Joachim , Spycher Jacques , Grazioli Véronique S , Bodenmann Patrick 
Published: May 2022

Abstract

Background
d/Deaf people suffer from inequitable access to healthcare and health information. This results in worse health literacy and poorer mental and physical health compared to hearing populations. Various interventions aimed at improving health equity for d/Deaf people have been documented but not systematically analyzed. The purpose of this systematic review is to obtain a global overview of what we know about interventions aimed at improving health equity for d/Deaf people.

Methods
Medline Ovid SP, Embase, CINAHL EBSCO, PsycINFO Ovid SP, Central—Cochrane Library Wiley and Web of Science were searched for relevant studies on access to healthcare and health-related interventions for d/Deaf people following the PRISMA-equity guidelines. We focused on interventions aimed at achieving equitable care and equitable access to health information for d/Deaf people.

Results
Forty-six studies were identified and analyzed. Seven categories of interventions facing healthcare or health education inequities emerged: use of Sign Language (1), translation, validation and identification of clinical tools and scales (2), healthcare provider training program (3), development of adapted healthcare facilities (4), online interventions (5), education programs (6) and videos (7). Despite some methodological limitations or lack of data, these interventions seem relevant to improve equity of care and health education for d/Deaf people.

Conclusion
Interventions that promote healthcare equity, health education amongst d/Deaf patients and healthcare provider awareness of communication barriers and cultural sensitivity show promise in achieving more equitable care for d/Deaf patients. Meaningful engagement of d/Deaf individuals in the conceptualization, implementation and evaluation of health-related interventions is imperative.