bluuebunny/crossref_metadata_2025_split huggingface dataset:
The health-related quality of life among the elderly in northwest China
Authors: Qi Mingrui , Bao Yun , Wang Wenjuan , Han Jing , Shi Zhao , Tian Limin 
Published: October 2022

Abstract
Objectives
This study aimed to evaluate health state utility (HSU) and compare the health-related quality of life (HRQoL) among elderly people in northwest China, and explore the factors affecting the HRQoL
Methods
In 2021, 1500 elderly were randomly recruited in Lanzhou, Gansu Province, the EQ-5D-5L and 15D scales were used to measure HRQoL and HSU. Descriptive analyses, such as demographic characteristics, socioeconomic status, etc. And the Tobit regression and multiple linear regression models were used to evaluate the related factors of HSU.
Result
A total of 1,320 older adults completed the study, and 35.3% elderly were normal weight; overweight elderly were 445(33.7%); obese elderly were 409 (31%). These elderly’s HSU was 0.941, 0.930, and 0.909 in the EQ-5D-5L, and in the 15D scale were 0.872, 0.858, and 0.845. Those aged 65–70, 70–75, 75–80 and above 80 HSU were 0.93, 0.927, 0.920 and 0.882 in the EQ-5D scale ( 0.867, 0.857, 0.850, and 0.837 in 15D). Males and females HSU were 0.939 and 0.918 ( 0.879 and 0.844 in 15D). Subgroup analysis, Tobit regression, and multiple linear regression showed that BMI, gender, age, marital status, and previous medical history were all related to the HRQoL of the elderly.
Conclusion
The EQ-5D-5L and 15D scales were used to measure the HSU of elderly people in northwest China and found overweight or obese, female, older age, marital status, and previous medical history. were closely associated with impaired HRQoL in the elderly.
Assessment of Vulnerability to Urban Floods in Greater Mumbai, India Using Geospatial Techniques
Authors: Mann Rohit , Gupta Anju 
Published: October 2022

Abstract

Urban flooding as well as its socio-economic repercussions is dramatically escalating globally in several coastal cities due to changes in rainfall patterns triggered by climate change. The principal aim of the study is to evaluate the flood vulnerable locations in Mumbai by using a multi-criteria evaluation (MCE) approach. The weights of flood-vulnerable impacting parameters like rainfall, slope, land use/cover (LULC), vicinity to sewers and storm water drainage, vicinity to natural drainage, vegetation, and soil are evaluated using the Analytical Hierarchy Process (AHP). The weights for said parameters are determined by using AHP, and they are as follows: rainfall (29.42%), slope (20.96%), LULC (17.52%), vicinity to sewers and storm water drainage (13.99%), vicinity to natural drainage (8.97%), vegetation (5.58%), and soil (3.56%). In the study area, it is estimated that 46.72% of the area is classified as being severe vulnerable, 18.74% of the area as high to very high and just 34.54% of the area as slight to moderate. Researchers were able to validate the modelling conclusion by examination of all 234 water-logged locations in the study area. Most of the water-logged spots i.e. 85.46% were found in areas that fall under the category of severe to very high vulnerability and only 14% of locations fall in other three categories as per the data of the flooding sites that are collected from MCGM authorities. These model-based flood vulnerable scenario maps are crucial for planning flood conservation and control measures to prioritize the area based on the degree of vulnerability.
The association of collaterals with myocardial ischemia and viability in chronic total occlusions
Authors: Leite Luís , Campos Gustavo , Silva Rodolfo , Jorge Elisabete , Oliveira-Santos Manuel , Gomes Andreia , Gonçalves Lino , Castelo-Branco Miguel , Abrunhosa Antero , Ferreira Maria João 
Published: October 2022

Abstract
Collateral development in chronic total occlusions (CTO) is crucial to perfuse the distal myocardium and its angiographic evaluation is frequently used to assess the need for revascularization. We aimed to analyse the association between the presence of ischemia and hibernating myocardium, evaluated by cardiac [13N]NH3/2-[18F]FDG PET-CT, and the angiographic characterization of the collateral circulation. Prospective study including patients with a CTO who underwent a [13N]NH3 and, when deemed necessary, 2-[18F]FDG PET-CT. Well developed (WD) collaterals were defined as a concomitant angiographic Rentrop grade 3 and Werner collateral connection score 2 or 3, whereas the remaining as poorly developed (PD). Two percentage thresholds used to identify prognostic benefit of revascularization were applied: ischemia >10% and hibernating myocardium >7%. Fifty-nine patients (age 62.9±9.1 years, 58 male) were recruited, WD collaterals were present in 28 (47.5%). No significant differences were found in ischemia (WD 6.4±4.3 vs. PD 7.0±4.1, p=0.64) and hibernation (WD 1.8±1.9 vs. PD 3.1±3.3, p=0.18) scores. Most CTO territories demonstrated ischemia, but only 19 (46.3%) were associated with an area >10% (WD 47.6% vs. PD 45.0%, p=0.58). Scared non-viable myocardium was limited to 9 (15.3%) patients and was not associated with PD collaterals. Hibernating myocardium was frequent (54.2%), but just 6 (10.2%) CTO patients had an area of >7% (WD 3.6% vs. PD 16.1%, p=0.20). Collateral assessment by angiography has a poor association with the ischemic burden and hibernation state of CTO territories. Myocardial viability was present even in most CTO with angiographic PD collaterals.
PEGylated emissive CdSe/ZnS@Fe2O3 nanocrystals for the UV mediated superior degradation of methylene blue
Authors: Ekici Derya Dincyurek , Mutlugun Evren 
Published: October 2022

Abstract
This work focuses on the degradation of methylene blue (MB), which has a toxic effect in water and cannot be completely removed by classical methods, i.e. under UV light. Photocatalytic nanoparticles produced in heterogeneous structure were carried out by examining the interaction of MB with our pegylated core-shell CdSe/ZnS@Fe2O3 nanocrystals under UV light in a dye-stuff solution medium. In our study CdSe/ZnS@Fe2O3 nanoparticles were synthesized and then, PEG has been attached to the surface upon careful surface engineering. The amount and time of catalyst upon degradation of MB under these conditions were investigated. The PEG:(CdSe/ZnS@Fe2O3) nanocomposite enable the degradation of MB with a photocataliytic degradation rate of 16,5*10− 3 min-1 in 30 mins, which is found to be more than 4,9 times when compared with the pegylated bare Fe2O3. It is worth noting that further optimizing the PEG:(CdSe/ZnS@Fe2O3) and the MB ratio the reaction rate reaches the maximum level of 63,12*10− 3 min-1. The PEG-(CdSe/ZnS@Fe2O3) nanocomposite exhibited a photocatalytic degradation efficiency of 84,2% within 30 min for methylene blue under visible light.
Family history of Glaucoma in patients diagnosed with Systemic Hypertension and Diabetes: The Colombian Glaucoma study.
Authors: Rivera Carlos Eduardo , Libreros-Peña Laura , Hernández Carlos Andrés , Morales Valentin , Marulanda Jesús , Ferreira Maria Catalina , Shah Ahsan , Aristizabal Juan Carlos , Muñoz Edgar , Seth Ankur 
Published: October 2022

Abstract

Background
It is estimated that worldwide, 76 million people have some type of glaucoma, 57.5 million are affected by Primary Open Angle Glaucoma (POAG), the relationship between family history of glaucoma and development of this disease has not been established so far in Latin American populations. We aim to establish the relationship between the Family History of Glaucoma in Colombian patients diagnosed with Systemic Hypertension (SH) and Diabetes Mellitus (DM).
Methods
We conducted a cross-sectional study among hypertensive and diabetic patients in Colombia, 2,067 subjects older than 50 diagnosed with SH or DM were included. Participants underwent to a complete ophthalmic and medical examination, standardized questionnaires, and interviews aiming to evaluate participants’ health conditions and lifestyles.
Results
In patients with a Family History of Glaucoma an OR: 2.11 ( 95% CI 1.33–3.34) was assessed for the presence of glaucoma, confirmed POAG was more frequent in men of all ages, patients from 70 to 79 years of age, OR: 0.54 ( 95% CI 0.36–0.79), and patients older than 80 years of age, OR: 0.47.
Conclusion
We established a relation between family history of Glaucoma in Colombian glaucoma patients diagnosed with SH and DM over 50 years of age. Screening for glaucoma should be recommended in high-risk groups, such as relatives of glaucoma patients.
Biodiversity conservation in the digital age, will Africa meet the challenge?
Authors: GANGLO Jean Cossi 
Published: October 2022

Abstract

Digital accessible Knowledge (DAK) is of utmost importance for biodiversity conservation; indeed, their use are indispensable to provide evidence and strategies to support decision-making on natural resource management and sustainable use. The Global Biodiversity Information Facility (GBIF, www.gbif.org) is a mega data infrastructure with more than two billion occurrence records as of 28th May 2022. It is by far the largest initiative assembling and sharing DAK to support scientific research, conservation, and sustainable development. We decided to analyze plant data published on GBIF site at the scale of Africa. This will highlight the contribution of the continent to GBIF and thereby underline data gaps across taxonomic groups, basis of records, and geographic space. In order to achieve our purpose, we downloaded data of the Plantae kingdom from Africa. They are available at https://doi.org/10.15468/dl.f79228. We achieved data treatment and analysis using R, several packages and related functions. Although Africa is home to a rich biodiversity with many hotspots, the global data contribution of Africa to GBIF is still incredibly low (1.37%). Furthermore, there are huge disparities between African countries with South Africa contributing alone for 65% of the data of the continent. The plant data of Africa (2,713,790 occurrence records) accounted for 9.11% of the data of the continent; this underlines huge gaps between taxonomic groups. Furthermore, the Magnoliopsida is the dominant plant class with the highest number of records (79.62%) and the highest number of species (71.85%) followed by the Liliopsida with 15.10% of the records and 18.16% of the species. Two basis of records were dominant: preserved specimens (75.49%) and human observation (18.60%). In geographic space, plant data gaps are also quite huge across the continent at either spatial resolution (half degree or one degree spatial grid cells); data completeness is more achieved in West Africa, East Africa, Southern Africa, and Madagascar. The huge multidimensional data gaps identified in this study should be in priority addressed in the future data collections. Accessibility either by roads or waterways and protected areas are underpinning factors of data completeness across the continent. We deplored important data loss during the process of data cleaning; indeed the total number of records with adequate coordinates accounted for 71.03% of the initial data while the data fitness for use in completeness analysis (records with adequate coordinates and full dates) are only about 65% of the total data records initially downloaded.
Grünes Kartellrecht: Wettbewerbspolitisches Plädoyer für einen «more environmental approach»
Authors: Bremer Frank , Ritz Michèle 
Published: October 2022

Die Bewahrung der Umwelt erweist sich immer mehr als überlebenskritische gesellschaftliche Generationenaufgabe. Obschon der Fokus auf staatlichen Massnahmen liegt, ist auch die Mitwirkung der Wirtschaft und damit der den Regeln des Kartellgesetzes unterstehenden Marktteilnehmer unabdingbar. Das schweizerische Kartellgesetz verfügt über vielfältige Schnittstellen für die wettbewerbliche Berücksichtigung von Umweltbelangen. Dies betrifft insbesondere die Beurteilungsgrundsätze für Wettbewerbsbeschränkungen durch Umweltabreden und die Berücksichtigungsfähigkeit pro-kompetitiver Umwelteffizienzen. Die Wettbewerbsbehörden stehen dabei im Sinne eines «more environmental approach» in der Verantwortung, die Voraussetzungen für eine Rechtssicherheit vermittelnde umweltkartellrechtliche Anwendungspraxis zu schaffen und damit die Transformation in eine grüne zukunftsfähige Wirtschaft proaktiv mitzugestalten.
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La préservation de l'environnement constitue une responsabilité sociale critique pour la survie des générations actuelles et futures. Bien que l'accent soit mis sur les mesures étatiques, la participation des acteurs du marché soumis aux règles de la loi sur les cartels est également indispensable. La loi suisse sur les cartels permet de considérer les questions environnementales et peut fournir aux entreprises en Suisse des réponses concurrentielles aux défis environnementaux. Cela concerne notamment les principes d'évaluation des restrictions à la concurrence par des accords environnementaux et la prise en compte des rendements environnementaux dans une perspective pro-concurentielle. Dans le sens d'une « more environmental approach », les autorités de concurrence ont la responsabilité de mettre en œuvre un droit des cartels environnemental garantissant la sécurité juridique et de participer ainsi de manière proactive à la transition vers une économie verte et durable.
Characteristics and performance analysis of different grain sizes bamboo-activated carbons for motorcycle flue gas adsorption
Authors: Negara Dewa Ngakan Ketut Putra , Nindhia Tjokorda Gde Tirta , Sucipta Made , Widiyarta I Made , Hariwangsa I Putu 
Published: October 2022

The use of fossil fuels in human activities such as motorcycles has led to an increase in the concentration emitted in the atmosphere. Various efforts and methods such as adsorption using activated carbon have been developed and applied to reduce the emission. Therefore, this study focuses on the characteristics and performance of bamboo-activated carbons in the adsorption of motorcycle flue gases. This was carried out using different grain sizes (z) of activated carbons AC-M1, AC-M2, and AC-M3 for grain sizes of z≤250, 250<z≤420, and 420<z≤590 microns, respectively, which were derived from swat bamboo and carbonized at a temperature of 750 ○C. Furthermore, physical activation was applied by heating the charcoal at the same temperature under a nitrogen flow rate of 150 mL/min nitrogen. The Thermogravimetric (TGA), scanning electron microscopy (SEM), and adsorption isotherm tests were employed for the characterization of activated carbons. Additionally, the performances of activated carbons for motorcycle flue gas adsorption (CO2, CO, and HC) were carried out by a motorcycle emission test. According to the results, activated carbon AC-M1 produced the best characteristics and performance for adsorption of motorcycle flue gas, as it has a pore volume of 0.135 cm3/g, a specific surface area of 244.69 m2/g, and a nitrogen adsorption capacity of 87.047 cm3/g. These characteristics prove to have good adsorption efficiencies at 100 %, 87.30 %, and 100 % for adsorption of CO2, CO, and HC, respectively.
Experimental determination of the heat exchange coefficient of industrial steam pipelines
Authors: Kostov Konstantin , Ivanov Ivan , Atanasov Koycho , Nikolov Chavdar , Kalchev Stefan 
Published: October 2022

The article discusses and analyses the factors related to the use of a thermal imaging camera to determine heat loss in industrial steam pipelines at factories from chemical and metallurgical industry, by measuring their surface temperature. The generally accepted enthalpy method for determination of the loss has serious drawback it gives accurate results, but in averaged units in which it is impossible to take account of the contribution of the different parts and components of the pipeline in the total heat loss. The unavailability of information on where, how and in what way along the route this loss is formed does not allow prompt and specific measures to be taken for its reduction. An attempt has been made to structure empirically a reliable analytic dependence for determination of the heat exchange coefficient, bringing together the various factors influencing the heat exchange. By the method of the least squares the free coefficient and the exponent have been determined of criterion equation satisfying initial and boundary conditions of the experiment. Based on the obtained results for determining the heat losses by measuring the surface temperature of steam pipelines with a thermal imaging system, a reliable and acceptable method is proposed, which has a place in engineering practice. For this purpose, an industrial experiment has been carried out at three actually operating steam pipelines of different diameters and steam parameters. A criterion equation has been derived that can be used as a mathematical model for software products with a practical orientation for regular assessment of heat losses of steam pipelines. Values of heat losses determined through energy balance of heat carrier and heat flux from the outer surface of the steam pipelines have been compared. Results for the heat exchange coefficient, obtained through a balance have been compared with the analytically determined values based on current standards. A new method has been developed for express evaluations of the current heat losses of the steam pipeline in real time, as the sum of the losses through its individual components gives as average values 9÷12 % increased results for the losses compared to the enthalpy method. Its great advantage is that it can be used selectively to determine the losses through individual sections of the steam pipeline.
Interaction of cyanidin with a hydroxylated surface (kaolin), modeling the effect of pН
Authors: Kaurkovska Veronika , Kaurkovska Kateryna 
Published: October 2022

The development of interest in anthocyanins in recent years is associated with an increase in the range of applications of these natural glycosides, contained in plants and berries, the color changes from red to blue with increasing pH. In addition to coloring properties (clay, fabric, hair), the use of anthocyanins – components of red and blue berries (including blueberries) – helps to reduce the risk of cardiovascular disease, Parkinson's disease and more.Most practical studies concern the interaction of anthocyanins with surfaces (clay, tissue, gastrointestinal mucosa, etc.) that have many hydroxyl groups. Therefore, the question of determining the approximate pH range is relevant, in which such an interaction is most likely. The aim of the work was to determine the priority form of the dye (according to the pH of the medium), which can be better fixed on the surface of kaolinSimulation of the interaction of cyanidin with the surface of white clay was performed by the Hartree-Fock-Rutaan method, using the GAMESS software package.The paper presents the results of modeling the interaction of different forms of the anthocyanin model – cyanidin (the content of cyanidin in plants is 50 % of the mass of all types of anthocyanins) in solutions with pH<3 (red – forms of cyanidin), 3<pH<7 (violet) and pH>7 (blue) with a hydroxylated surface of white clay – kaolin, having different types of hydroxyl groups.
The aglycone part of the cyanidin molecule artificially was approached at a distance of approximately 2.5 Å to the surface of kaolin.
It was shown, that the quinoid form of cyanidin (violet) was the most active of the three forms, mainly in interaction with the silanol groups of the kaolin surface. The form of cyanidin at pH<3 (red) have the lowest energies of interaction with the surface of kaolin
E. Coli expression of functionally active cellular targeting motif of human focal adhesion kinase
Authors: Healy Judith M. , Yamaguchi Ryuji , Jingamil Hisato 
Published: October 2022

Abstract:
Focal adhesion kinase (FAK) is a structurally distinctive cytoplasmic tyrosine kinase which localizes to
cellular focal contacts. Sequences near the C-terrninus of FAK, termed the focal adhesion targeting (FAT) domain,
are responsible for localization of FAK to focal adhesion complexes. Here, we report expression in E. coli of Cterminal fragments of human FAK containing the FAT domain as epitope-tagged fusions. Purified bacterially derived
FAT domains were biologically active and their far ultraviolet circular dichroism spectra showed evidence of
extensive alpha-helical secondary structure,
NMR investigation of a microtubule binding region peptide from human tau ('t) protein
Authors: de Serrano Vesna , Ribeiro Anthony A. , Strittmatter Warren J. , Spicer Leonard D. 
Published: October 2022

Abstract:
Solution NMR studies of 1:Dl, an 18-residue microtubule binding peptide from domain 1 of human tau protein, are reported. Using 2D I H NMR (TOCSY, NOESY and ROESY) at 5 and 37 oc, we assigned the resonances of almost all protons of 1:Dl at pH 4.2, 5.8 and 7.3. While overall the peptide is highly disordered, several medium range NOE's give evidence for conformational preferences involving a bend at the T8-Q14 segment of the peptide.
Arginine and peptidyl oximes are able to inhibit both proprotein convertases pcl and furin
Authors: Basak Ajoy , Lazure Claude 
Published: October 2022

Abstract:
Various Arginine derivatives bearing a modified carboxyl function such as oxime, hydroxamate, N,O-dimethyl hydroxamate, O-methyl oxime and O-methyloxy carbonyl oxime were able to inhibit the enzymatic activities of hPCl and hfurin towards a fluorescent peptidyl substrate. In an effort to improve the inhibition, a tetrapeptide containing a C-terminal arginine oxime, Arg-Lys-Lys-Arg-CH=NOH was prepared and, together with a side reaction product, Arg-Lys-Lys-Arg-C(NHOH)(OH)-N(OMe)Me, exhibited a much enhanced level of inhibition.
Crystallization and preliminary x-ray analysis of mouse pro-renin converting enzyme
Authors: Blaber Michael 
Published: October 2022

Abstract:
Hexagonal crystals (P64) of mouse pro-renin converting enzyme (PRECE) have been grown which diffract to better than 2.5A. A native data set has been collected with 93% completion from 20 to 3.0A. Using molecular replacement, with porcine kallikrein (PPK) as a search model (56% amino acid identity), a solution for a single molecule in the asymmetric unit has been identified. Refinement of the correctly positioned PPK model, against the PRECE dataset, has resulted in a PRECE model with an Rrac10, of24.7% and an Rrrec of32.8%.
Aspartic protease inhibitors: synthesis of a radiolabelled fatty acid linked pepstatin
Authors: Bessodest Michel , Antonakis Kostas , Rougeot Christian , Capony Francoise , Garcia Marcel , Rochefort Henri 
Published: October 2022

Abstract:
To improve the bioavailability of the inhibitor of aspartic proteases, pepstatin A, the synthesis of a tritium labelled fatty acid derivative and its condensation with the C-terminal of pepstatine was performed. A comparative study of the inhibition properties of the title compound with pepstatin A was made.