bluuebunny/crossref_metadata_2025_split huggingface dataset:
Buying vaccines through a single payment as a proxy for procuring vaccines via formularies
Authors: Alves-Maciel Bruno , Proano Ruben A. 
Published: August 2022

Abstract
In this study, we evaluate the possibility of making vaccines more affordable without impacting profits by exploring the effects of selling vaccines as formularies or baskets of vaccines bundled in the same sale. Assuming that countries are grouped into market segments for tiered pricing purposes and are coordinated by a single decision-maker, we propose selling vaccines as formularies by changing their pricing scheme so that buyers make a single lump-sum payment to each vaccine producer for their vaccines. Results show that changing the pricing scheme can improve affordability.
Retinal vascular density changes following phacoemulsification versus phacotrabeculectomy for primary angle-closure glaucoma: A comparative study
Authors: Daneshvar Ramin , Karimi Farshid , Azimi Abbas , Khorrami-Nejad Masoud , Tireh Hossein , Moghaddam Somayeh Ghasemi 
Published: August 2022

Abstract

Purpose:To compare retinal vascular density changes following phacoemulsification vs. phacotrabeculectomy for primary angle-closure glaucoma(PACG).Materials and methods:Sixty-seven glaucoma patients were evaluated in a single center, and those with concomitant PACG and senile cataracts and without a history of prior ocular surgeries, trauma, or monocular status use were recruited. Finally, 59 eligible subjects were assigned to phacoemulsification (‘Phaco’ group, 29 eyes) or phacotrabeculectomy (‘Combined’ group, 30 eyes) surgeries based on the clinical situation. A commercial optical coherence tomography angiography (OCTA) device was used to measure the retinal vascular density and retinal nerve fiber layer thickness before, one week, one month after surgery.Results:For the RNFL thickness in different areas, a significant difference was found between the pre- and postoperative value only in the nasal area in the 'Combined' group (P<0.05). Among different vascular parameters, ‘inside disc vessel density’ had a significant difference for both ‘all vessels’ and ‘capillaries’ (p<0.05). Furthermore, ‘superficial hemifield vessel density for all vessels’ significantly changed after combined surgery (p=0.049).Conclusions:Despite similar IOP control, the vascular changes following phaco and combined surgery in PACG patients may be different, contributing to functional outcomes of these therapeutic modalities.
Ovarian reserve decreases in women with Crohn's disease: clinical characteristics and risk factors-a case control study
Authors: Xiang Peng , Yao Jia-yin , Li Xiao-lan , Zhang Min , Hu Pin-jin , Zhi Min 
Published: August 2022

Abstract
Background:Crohn’s disease(CD), often occurring in women of child-bearing age, can decline the fertility rate. However, whether it reduces ovarian reserve has been rarely reported. This study aimed to evaluate the ovarian reserve in women with CD from the perspective of anti-müllerian hormone(AMH), and explore the factors that can decrease ovarian reserve. Methods: A case-control retrospective study was designed. We analyzed the AMH levels in a total of 135 CD women and 878 healthy controls. Then using the technique of propensity score matching, the subjected were grouped in a ratio of 1:3, according to age, body mass index and smoking status. Finally, 121 patients were included into the CD group, and 324 into control group, with similar basic characteristics. Serum AMH levels were measured by chemiluminescence.Results: The AMH level in the CD group was significantly lower than that in the control group (2.17±2.23ug/L vs 3.95±2.01ug/L, 95%CI[1.34-2.21], P<0.001). In both groups, the AMH levels decreased as age increased, but without between-group difference in the decreasing rate (P=0.639). Multivariate analysis showed that age>30 years (OR,2.905;95%CI[1.053-8.531], P=0.017), disease activity (OR,4.314; 95%CI[1.561-12.910], P=0.002) and thalidomide use (OR,12.628; 95%CI[4.351 -42.820], P<0.001) were independent risk factors associated with decreased ovarian reserve (AMH＜1.1ug/L). Conclusion: Ovarian reserve is lower in CD women than in healthy women. Age, CD activity and medication of thalidomide are risk factors that an aggravate the decline of ovarian reserve.
Performance Analysis of Hermite Gaussian 8×40 Gb/s DWDM-FSO System using Advance Modulation Schemes
Authors: Sinha Shivaji , Kumar Chakresh 
Published: August 2022

AbstractTransmission of high-speed optical signals across the free space channel is highly dependent on external characteristics such as scintillation and attenuation as a result of atmospheric conditions that are constantly changing. This paper describes the architecture of an 8×40 Gbps dense wavelength division multiplexed (DWDM)-FSO transmission system based on Hermite Gaussian (HG) channels and incorporates various advanced modulation techniques. In addition, the implementation of a spatial mode laser and an optical boost amplifier decreases the effect of degradation caused by atmospheric attenuation and extends the optical link distance. The performance of the proposed system design is investigated for six modulation schemes including 64-QAM, 16-QAM, 4-QAM, 8-PSK, DPSK, and DQPSK modulations in different atmospheric attenuations conditions under a strong Gamma-Gamma (GG) turbulent channel. It is reported that the optical link performance degrades exponentially with an increase in signal to noise ratio (SNR) for the modulation schemes listed above. 4-QAM and DPSK modulations outperform the rest of the modulation methods for low SNR values as the optical link distance increases. The successful signal transmission of 8×40 Gb/s data over the transmission link distance of about 5 km with an acceptable BER level of 10− 6is achieved.
Probabilistic Behavior Assessment of Semi-Flexible and Flexible Base-Isolated Buildings
Authors: Karimi Mohammad Reza Bagerzadeh , Geneş Mehmet Cemal 
Published: August 2022

Abstract
Despite the well-known mechanical properties of the Lead Core Rubber Bearing (LCRB) system, it can act variously under different forms of ground motion with various components. Since the performance of seismically isolated buildings is unpredictable and varies under the several types of ground motions with different components, and as it depends on the variation of the mechanical properties of the base isolation systems, the probabilistic behavior of the semi-flexible and flexible base-isolated buildings has been evaluated in terms of preserving the structural system and vibration-sensitive contents. In this direction, four important key parameters of the LCRB system have been considered as variable parameters, and 94 pulse-like ground motions, whose pulse period ranges between 0.5 sec and 13 sec, have been selected from PEER strong ground motion database center. In this respect, a Monte Carlo simulation was performed and 28200 time-history analyses were implemented for each of the buildings selected in this study. Finally, detailed insight into the variability of seismic response was given to understand the behavior of the base-isolated buildings and the effect of the mechanical parameters of the base isolation systems considering the different components of the pulse-like ground motions.
Patterns of coexistence between two mesocarnivores in presence of anthropogenic disturbances in Western Himalaya
Authors: Bandyopadhyay Meghna , Biswas Suvankar , Dasgupta Tryambak , Krishnamurthy Ramesh 
Published: August 2022

Abstract
Species' coexistence depends on species-specific resource utilization in a given habitat. Human disturbances in this context can constrain the realized niche by altering their community dynamics. In this study, we considered Western Himalaya as a case study to test the hypothesis that human disturbances influence mesocarnivore coexistence patterns. We regarded red fox and leopard cat as the focal species and assessed the coexistence patterns in low and high human disturbance areas in three dimensions: spatial, temporal and dietary habit. We used camera trap detections and mitochondrial DNA-based species identification of faecal samples. We used generalized linear mixed-effect modelling (GLMM), activity overlap, Levin’s niche breadth and Pianka’s overlap index to capture the spatial, temporal and dietary interactions respectively. We found that red fox and leopard cat coexisted by spatial segregation in low human disturbance area, whereas dietary segregation was the means of coexistence in high human disturbance area. We observed a broader dietary breadth for red fox and a narrower for leopard cat in high human disturbance area. The altered coexistence pattern due to differential human disturbances indicates intensive anthropogenic activities adjacent to natural forests. It can link to increased opportunities for shared spaces between mesocarnivores and humans, leading to future disease spread and conflicts. Our study contributes to scant ecological knowledge of these mesocarnivores and adds to our understanding of community dynamics in human-altered ecosystems. The study elucidates the need for long-term monitoring of wildlife inhabiting interface areas to ensure human and wildlife coexistence.
Improvement of lamination process of banana pseudo stem/polylactic acid: mechanical-thermal and biodegradation analysis
Authors: Kittikorn Thorsak , Jitjaicham Sujinda , Chanwetwirot Chinchuta , Malakul Ramitanun , Kadea Suding 
Published: August 2022

Abstract
This research was to investigate the effect of silanization of 3-(trimethoxysilyl) propyl methacrylate of polyvinyl alcohol (PVA) as a binder and compatibilizer for the production of a pulp fibre sheet based agricultural waste of banana pseudo stem fibre and laminating with polylactic acid (PLA), respectively. The modification of PVA was successful by a confirmation of FTIR. As a result of mechanical-thermal analysis (DMTA), the modified PVA performed prominence as a compatibilizer in the combination of PLA and pulp sheet for the lamination process. It influenced to improve storage modulus roughly up to 50% while performing more viscous. Similarly, the tensile test also confirmed the improved properties. Interestingly, the biocomposite laminate as used in the modified PVA showed more hydrophilic rather than unmodified. A microbial growth test by Aspergillus niger also revealed the modified PVA influencing more severe biodegradation on the laminate.
Consumer perception of brand equity based on environmental sustainability in the Amazon: development and validation of a scale
Authors: Diego Luiz , Holanda Francisco Sandro Rodrigues 
Published: August 2022

Abstract
PurposeBrands gradually became the core dimension and strategic asset of branding for organizations of all sizes, and today many companies adopt various forms of green marketing activities as part of their strategies. In this sense, this study aimed to develop and investigate the psychometric properties of precision and validity of a scale for brand evaluation equity based on the environmental sustainability of the Amazon in the Brazilian context.Design/methodology/approachThe scale was validated by adopting the norms described in the Standards standards. As samples for testing, eight companies from the Amazônia UP program participated in this research, having data interviews applied to 262 potential consumers.discoveriesA scale with 23 items was constructed and validated, and after evaluation by the specialists, 22 items were obtained, divided into four dimensions: Quality perception — POQ(5 questions); Strategic Brand Positioning – SBP (10 questions); Willingness to buy — WIB(2 questions) and Innovation in retail — BRI (4 questions). Three items were modified because they presented the CVC at 0.8, being accepted after the adjustments. The instrument items showed good internal consistency (0.877) regarding their domains. As for DIF data, the scale invariably works for older and younger people for almost all items, except item BRI 04.Research limitations/implicationsThis article fills the gap in the literature by developing a scale to assess consumer perception of brand equity and environmental sustainability. However, the findings are limited to the variation in the data collection since, as a result of the COVID-19 pandemic period, most participants chose to fill in the scale online. Thus, the scale data are limited by the context in which the research was applied.practical implicationsThe development and subsequent validation of the contextualized psychometric scale fills an important gap in the academic literature, providing a better understanding of the perception of potential consumers about the brand. Sustainable brand equity that generalist scales could not measure. Likewise, the scale provides essential information for brand entrepreneurs who aim to develop their products sustainably, an important tool for managers to test and validate the extent to which new advertising materials demonstrate brand authenticity.Originality/ValueThe present study contributes to the directional and effective branding of brands related to environmental sustainability, mainly from tropical forests such as the Amazon rainforest. Furthermore, the findings suggest that the instrument developed and validated cross-culturally can be applied to potential consumers aged between 19 and 64 years of both sexes.
Given Names Change Consumption Decisions: Evidence from the Female Body Image Market in China
Authors: fang Zhou , Bian Yong 
Published: August 2022

Abstract
Names play important roles in Chinese culture; people often obtain their first impression of others by interpreting their names. As “feminine qualities” are favored in the naming of girls, many females receive names with implications of beauty in China. How do these names impact the life of Chinese females? In this paper, which uses survey data from 314 Chinese female as a sample, we tested the impact of beauty in a name on people’s consumption decisions in the body image market. According to the results of a ordinary linear regression, we found that a direct implication of beauty in names results in an increase of 9.51k CNY in appearance improvement consumption on average, which is approximately 43% of the average spending in appearance improvement in our sample.. Additionally, with mediation analysis, we found that this impact is partly caused by the Chinese culture in which people obtain impressions of others through their given names.
Modified Variational Iteration Method with Chebyshev Polynomials for Solving 12th order Boundary Value problems
Authors: Tsetimi Jonathan , K.O Ogeh , A. B Disu 
Published: August 2022

We consider in this paper an illustration of the modified variational iteration method (MVIM) as an effective and accurate solver of 12th order boundary value problem (BVP). For this reason, the Chebyshev polynomials of the principal kind was utilized as a premise capabilities in the guess of the logical capability of the given issue. The strategy is applied in an immediate manner without utilizing linearization or irritation. The subsequent mathematical confirmations recommend that the strategy is without a doubt successful and exact as applied to a few direct and nonlinear issues as mathematical trial and error. Maple 18 was used for all computational simulations carried out in this research.©2022 JNSMR UIN Walisongo. All rights reserved.
Changing academics’ ways of working: towards a distributed university campus
Authors: Migliore Alessandra , Tagliaro Chiara , Ciaramella Andrea 
Published: August 2022

Academics are a peculiar category of knowledge workers whose work, by nature, is characterized by undefined time and space and includes individual and collaborative activities. Over the past decades, academics have progressively evolved their typically university-centric way of working towards a hybrid, spatially distributed model that includes home and other spaces. The spread of the Covid-19 pandemic has accelerated the redrawing of the geography of workspaces for academics and has opened up opportunities to enable creative, innovative and socially sustainable ways of working. Indeed, working from other spaces than the official workplace can not only have positive impacts on productivity, creativity, and collaboration of academics and staff, but also increase the attractiveness and inclusivity of university campuses by proposing a campus model that is spread across the territory according to the individual needs of its users. While there are already some cases where university campuses accommodate coworking spaces, libraries and innovation hubs within them, evidence of academics using other spaces off-campus is scarce. This research investigates whether, and to what extent, the use of off-campus spaces by Italian academics is a likely and desirable prospect for the future, based on how much their way of doing research has evolved during the Covid-19 pandemic towards a multi-local way of working. A questionnaire was distributed among Italian tenured academics. This chapter presents a quantitative and qualitative interpretative analysis of the data collected from 1,199 answers to this questionnaire. Results describe different profiles of multi-local Italian academics, in relation to the types of location they work from, the experience they had during the Covid-working period and the future they wish for at university campuses. The evidence on multi-local work presented in this chapter shows implications both for academic staff and for university management. The former could approach work in a more distributed way such as it would extend university campuses to an urban and extra-urban dimension. The latter are called upon to meet the needs of their staff using socially sustainable ways of managing their facilities within and beyond campus boundaries.
A study on drinking water quality in different income groups of Vizianagaram region of India
Authors: Reddy M. Kiranmai , Priyadarshini N. Priyanka , Singh Visakha , Suresh Reddy K.V.N. 
Published: August 2022

Abstract
Portable clean water consumption is the basic right of every individual. The major global concern is water pollution which can cause mortality. Change in physicochemical characteristics in drinking water is not only a pollution problem, but the presence of antibiotic-resistant microbes is also a significant issue. The study was carried out to assess the physicochemical and microbiological quality of the reservoir, municipality-supplied water, and bottled water. A total of 100 samples were collected from different income classes (higher, medium, and low) groups. The experiments were carried out based on the guidelines of APHA. In the present study, 40% of samples have been found to be contaminated with bacteria such as Escherichia coli, Vibrio cholerae, and Enterobacter aerogenes. Moreover, these bacteria also showed antibiotic resistance to certain drugs. The percentage of isolated bacterial strains was resistant to amoxicillin and ampicillin antibiotics. The statistical analysis of the Chi-square test states that there is a significant correlation between E. coli and other microbes (p ≤ 0.5). This study gives a piece of baseline information about the prevalence of antibiotic-resistant bacteria and focuses on the improvement of water from purification before reaching the consumer.
Chemotherapy and Anticancer Drugs Adjustment in Obesity: A Narrative
Review
Authors: Thimotheo Batista João Pedro , Santos Marzano Lucas Alexandre , Menezes Silva Renata Aguiar , de Sá Rodrigues Karla Emília , Simões e Silva Ana Cristina 
Published: August 2022

Background:
Obese individuals have higher rates of cancer incidence and cancer-
related mortality. The worse chemotherapy outcomes observed in this subset of patients
are multifactorial, including the altered physiology in obesity and its impact on
pharmacokinetics, the possible increased risk of underdosing, and treatment-related toxicity.

Aim:
The present review aimed to discuss recent data on physiology, providing just an
overall perspective and pharmacokinetic alterations in obesity concerning chemotherapy.
We also reviewed the controversies of dosing adjustment strategies in adult and pediatric
patients, mainly addressing the use of actual total body weight and ideal body weight.

Methods:
This narrative review tried to provide the best evidence to support antineoplastic
drug dosing strategies in children, adolescents, and adults.

Results:
Cardiovascular, hepatic, and renal alterations of obesity can affect the distribution,
metabolism, and clearance of drugs. Anticancer drugs have a narrow therapeutic
range, and variations in dosing may result in either toxicity or underdosing. Obese patients
are underrepresented in clinical trials that focus on determining recommendations
for chemotherapy dosing and administration in clinical practice. After considering associated
comorbidities, the guidelines recommend that chemotherapy should be dosed according
to body surface area (BSA) calculated with actual total body weight, not an estimate
or ideal weight, especially when the intention of therapy is the cure.

Conclusion:
The actual total body weight dosing appears to be a better approach to dosing
anticancer drugs in both adults and children when aiming for curative results, showing
no difference in toxicity and no limitation in treatment outcomes compared to adjusted
doses.
Present and Future Prospects of the Anti-cancer Activities of Saikosaponins
Authors: Jiao Zuo-Yi , Xiao Li-Xia , Zhou Hui-Nian 
Published: August 2022

Abstract:
Since their discovery, saikosaponins (SSs) have been found to play an important role in
treating a variety of cancers via diverse mechanisms of action. This review summarizes the current research
status and prospects of the anti-cancer activities of SSs, providing novel insights into the limitations
of current studies. In addition, it discusses whether SSs can be applied in immunotherapy and
the possible mechanisms by which SSs may facilitate immunotherapy. The research is significant to
understanding the anti-cancer potents of SSs in the development of SSs-based therapeutic strategies
and clinical practice.