bluuebunny/crossref_metadata_2025_split huggingface dataset:
A pipeline for assembling low copy nuclear markers from plant genome skimming data for phylogenetic use
Authors: Reginato Marcelo 
Published: December 2022

Background
Genome skimming is a popular method in plant phylogenomics that do not include a biased enrichment step, relying on random shallow sequencing of total genomic DNA. From these data the plastome is usually readily assembled and constitutes the bulk of phylogenetic information generated in these studies. Despite a few attempts to use genome skims to recover low copy nuclear loci for direct phylogenetic use, such endeavor remains neglected. Causes might include the trade-off between libraries with few reads and species with large genomes (i.e., missing data caused by low coverage), but also might relate to the lack of pipelines for data assembling.

Methods
A pipeline and its companion R package designed to automate the recovery of low copy nuclear markers from genome skimming libraries are presented. Additionally, a series of analyses aiming to evaluate the impact of key assembling parameters, reference selection and missing data are presented.

Results
A substantial amount of putative low copy nuclear loci was assembled and proved useful to base phylogenetic inference across the libraries tested (4 to 11 times more data than previously assembled plastomes from the same libraries).

Discussion
Critical aspects of assembling low copy nuclear markers from genome skims include the minimum coverage and depth of a sequence to be used. More stringent values of these parameters reduces the amount of assembled data and increases the relative amount of missing data, which can compromise phylogenetic inference, in turn relaxing the same parameters might increase sequence error. These issues are discussed in the text, and parameter tuning through multiple comparisons tracking their effects on support and congruence is highly recommended when using this pipeline. The skimmingLoci pipeline (https://github.com/mreginato/skimmingLoci) might stimulate the use of genome skims to recover nuclear loci for direct phylogenetic use, increasing the power of genome skimming data to resolve phylogenetic relationships, while reducing the amount of sequenced DNA that is commonly wasted.
Embedding Atomically Dispersed Iron Sites in Nitrogen‐Doped Carbon Frameworks‐Wrapped Silicon Suboxide for Superior Lithium Storage
Authors: Guo Xiaotian , Xu Hengyue , Li Wenting , Liu Yangyi , Shi Yuxin , Li Qing , Pang Huan 
Published: December 2022

AbstractSilicon suboxide (SiOx) has attracted widespread interest as Li‐ion battery (LIB) anodes. However, its undesirable electronic conductivity and apparent volume effect during cycling impede its practical applications. Herein, sustainable rice husks (RHs)‐derived SiO2 are chosen as a feedstock to design SiOx/iron–nitrogen co‐doped carbon (Fe–N–C) materials. Using a facile electrospray‐carbonization strategy, SiOx nanoparticles (NPs) are encapsulated in the nitrogen‐doped carbon (N–C) frameworks decorating atomically dispersed iron sites. Systematic characterizations including high‐angle annular dark‐field scanning transmission electron microscopy (HAADF‐STEM) and X‐ray absorption fine structure (XAFS) verify the existence of Fe single atoms and typical coordination environment. Benefiting from its structural and compositional merits, the SiOx/Fe–N–C anode delivers significantly improved discharge capacity of 799.1 mAh g−1, rate capability, and exceptional durability, compared with pure SiO2 and SiOx/N–C, which has been revealed by the density functional theory (DFT) calculations. Additionally, the electrochemical tests and in situ X‐ray diffraction (XRD) analysis reveal the oxidation of LixSi phase and the storage mechanism. The synthetic strategy is universal for the design and synthesis of metal single atoms/clusters dispersed N–C frameworks encapsulated SiOx NPs. Meanwhile, this work provides impressive insights into developing various LIB anode materials suffering from inferior conductivity and huge volume fluctuations.
Orthorhombic Nb2O5 Decorated Carbon Nanoreactors Enable Bidirectionally Regulated Redox Behaviors in Room‐Temperature Na–S Batteries
Authors: Huang Xiang Long , Zhang Xiaofeng , Zhou Liujiang , Guo Zaiping , Liu Hua Kun , Dou Shi Xue , Wang Zhiming 
Published: December 2022

AbstractRegulating redox kinetics is able to spur the great‐leap‐forward development of room‐temperature sodium–sulfur (RT Na–S) batteries, especially on propelling their Na‐ion storage capability. Here, an innovative metal oxide kinetics accelerator, orthorhombic Nb2O5 Na‐ion conductor, is proposed to functionalize porous carbon nanoreactors (CNR) for S cathodes. The Nb2O5 is shown to chemically immobilize sodium polysulfides via strong affinity. Theoretical and experimental evidence reveals that the Nb2O5 can bidirectionally regulate redox behaviors of S cathodes, which accelerates reduction conversions from polysulfides to sulfides as well as promotes oxidation reactions from sulfides to S. In situ and ex situ characterization techniques further verify its electrochemical lasting endurance in catalyzing S conversions. The well‐designed S cathode demonstrates a high specific capacity of 1377 mA h g−1 at 0.1 A g−1, outstanding rate capability of 405 mA h g−1 at 2 A g−1, and stable cyclability with a capacity retention of 617 mA h g−1 over 600 cycles at 0.5 A g−1. An ultralow capacity decay rate of 0.0193% per cycle is successfully realized, superior to those of current state‐of‐the‐art RT Na–S batteries. This design also suits emerging Na–Se batteries, which contribute to outstanding electrochemical performance as well.
Dihydrophenazine‐Based Conjugated Microporous Polymer Cathodes with Enhanced Electronic and Ionic Conductivities for High‐Performance Aluminum Dual‐Ion Batteries
Authors: Ma Wenyan , Luo Lian‐Wei , Huang Xiuhua , Dong Peihua , Chen Yu , Zhang Chong , Huang Fei , Jiang Jia‐Xing , Cao Yong 
Published: December 2022

AbstractIt is fundamentally challenging for cathode materials to achieve long life, high capacity, and fast kinetics in rechargeable aluminum batteries, due to the strong electrostatic interaction between Al3+ and the host materials. Herein, the redox‐active dihydrophenazine (Pz) is coupled with pyrene (Py) or biphenyl (Ph) to develop two conjugated microporous polymers of PyPz and PhPz as AlCl4−‐hosting cathodes for aluminum dual‐ion batteries (ADIBs). It is revealed that the planar Py unit endows PyPz with an extended conjugated skeleton and a higher surface area than PhPz produced from the Ph unit with a twisted structure, thus leading to a higher redox activity for PyPz. Hence, the PyPz cathode delivers a much higher capacity of 231 mAh g−1 than PhPz (137 mAh g−1). Its porous structure and insolubility also ensure PyPz shows a superior rate performance and exceptional cyclability over 100 000 cycles. Meanwhile, the feature of fast kinetics for AlCl4− storage also allows PyPz to operate well at not only a low temperature (−30 °C) but also a high areal capacity of 2.53 mAh cm−2. These findings suggest that redox‐active conjugated polymers are promising advanced organic cathodes for sustainable ADIBs, where the electrochemical performance can be significantly enhanced by rational structural design.
A Disordered Rubik's Cube‐Inspired Framework for Sodium‐Ion Batteries with Ultralong Cycle Lifespan
Authors: Peng Jian , Zhang Bao , Hua Weibo , Liang Yaru , Zhang Wang , Du Yumeng , Peleckis Germanas , Indris Sylvio , Gu Qinfen , Cheng Zhenxiang , Wang Jiazhao , Liu Huakun , Dou Shixue , Chou Shulei 
Published: December 2022

AbstractSodium‐ion batteries (SIBs) with fast‐charge capability and long lifespan could be applied in various sustainable energy storage systems, from personal devices to grid storage. Inspired by the disordered Rubik's cube, here, we report that the high‐entropy (HE) concept can lead to a very substantial improvement in the sodium storage properties of hexacyanoferrate (HCF). An example of HE‐HCF has been synthesized as a proof of concept, which has achieved impressive cycling stability over 50 000 cycles and an outstanding fast‐charging capability up to 75 C. Remarkable air stability and all‐climate performance are observed. Its quasi‐zero‐strain reaction mechanism and high sodium diffusion coefficient have been measured and analyzed by multiple in situ techniques and density functional theory calculations. This strategy provides new insights into the development of advanced electrodes and provides the opportunity to tune electrochemical performance by tailoring the atomic composition.
Furan‐Extended Helical Rylenes with Fjord Edge Topology and Tunable Optoelectronic Properties
Authors: Luo Teng , Wang Yanpei , Hao Jiahang , Chen Ping‐An , Hu Yuanyuan , Chen Bo , Zhang Jun , Yang Kun , Zeng Zebing 
Published: December 2022

AbstractLateral furan‐expansion of polycyclic aromatics, which enables multipleO‐doping and peripheral edge evolution of rylenes, is developed for the first time. TetrafuranylperyleneTPF‐4CNand octafuranylquaterryleneOFQ‐8CNwere prepared as model compounds bearing unique fjord edge topology and helical conformations. Compared toTPF‐4CN, the higher congenerOFQ‐8CNdisplays a largely red‐shifted (≈333 nm) and intensified absorption band (λmax=829 nm) as well as a narrowed electrochemical band gap (≈1.08 eV) due to its pronounced π‐delocalization and emerging of open‐shell diradicaloid upon the increase of fjord edge length. Moreover, strong circular dichroism signals in a broad range until 900 nm are observed for open‐shell chiralOFQ‐8CN, owing to the excellent conformational stability of its central bis(tetraoxa[5]helicene) fragments. Our studies provide insights into the relationships between edge topologies and (chir)optoelectronic properties for this novel type ofO‐doped PAHs.
Rapid synthesis of conjugated linoleic acid from fruit processing residues seed oil by alkali‐dimethyl sulfoxide isomerization
Authors: Pojjanapornpun Siriluck , Sombutsuwan Piraporn , Chumsantea Salisa , Nakornsadet Akkaradech , Krisnangkura Kanit , Aryusuk Kornkanok 
Published: December 2022

AbstractRapid synthesis of conjugated linoleic acid (CLA) by the alkali‐dimethyl sulfoxide (DMSO) isomerization method is presented in this study. Seeds from fruit processing residues in Thailand were screened as an alternative potential source of linoleic acid (LA)‐rich oil. Passion fruit with 72.10% LA and 26.18% oil in the seeds was selected as starting oil. The Alkali‐DMSO isomerization was carried out by mixing DMSO with alkali hydroxides and polyhydric alcohols. Under a mass ratio of 1:0.5:1:1 oil/NaOH/propylene glycol/DMSO, at 180°C, production of the major isomers of CLA (c9,t11, and t10,c12) was complete within 3 min, resulting in a 20‐fold increase in productivity compared to the conventional method. The reaction time decreased because of an increment in the basic strength of the alkali‐DMSO catalyst. CLA from alkali‐DMSO isomerization and commercial supplements showed a similar isomer distribution and yielded similar CC50 values when evaluated against the Vero cell line. This method might be an alternative in industrial production as it is fast and simply applied to the conventional system. In addition, seed oils from fruit processing residues can be used as an alternative to traditional LA‐rich oils.
Building Performance Simulation an der RWTH Aachen University – Serie: Gebäudesimulation und Berechnungstools in der Lehre
Authors: Frisch Jérôme , van Treeck Christoph 
Published: December 2022

AbstractDiese Artikelserie stellt den Einsatz von Computerprogrammen in der Hochschullehre der Bauphysik und Gebäudetechnik für Architekten und Bauingenieure vor.Seit 2013 wird an der RWTH Aachen University am Lehrstuhl für Energieeffizientes Bauen E3D das Fach „Energetische Gebäudesimulation“ angeboten. Zielgruppe bilden die Kernstudiengänge „Bauingenieurwesen“, „Umweltingenieurwissenschaften“ und „Wirtschaftsingenieurwesen, Fachrichtung Bau“ im Masterstudium an der Fakultät für Bauingenieurwesen. Ziel der aktuellen Lehrveranstaltung ist es, den Studierenden die theoretischen und praktischen Grundzüge der energetischen Gebäudesimulation zu vermitteln. Hierzu werden die theoretischen Grundlagen modular aufbereitet und detailliert in der Vorlesung vorgestellt. In der Übung werden die Grundlagen der Programmierung vermittelt oder aufgefrischt. Anschließend werden modular Teilkomponenten für eine Simulation in der Sprache Modelica selbst implementiert und programmiert. Dies ermöglicht es den Studierenden in angemessener Art und Weise durch die komplexe Themensammlung zu schreiten und sich mit Themen tiefgehend zu beschäftigen, die bei einer rein anwendungsbezogenen Sicht auf ein existierendes Gebäudesimulationsprogramm sicherlich zu kurz kommen würden.
Einfaches und schnelles dynamisches Modell für die Vorhersage des PV‐Eigenverbrauchs
Authors: Ochs Fabian , Dermentzis Georgios 
Published: December 2022

AbstractDer breite Einsatz erneuerbarer Energien spielt eine entscheidende Rolle bei der Steigerung der Energieeffizienz des Gebäudebestands. Deutlich gesunkenen PV‐Anlagenpreise und die hohe Flexibilität bei der Stromnutzung für alle Verbraucher in einem Gebäude, also Raumheizung (und ‐kühlung), Warmwasserbereitung in Kombination mit Wärmepumpe, Hilfsenergien, Haushaltsgeräten und zunehmend auch Mobilität führt zu einem breiten Einsatz von PV. Jedoch ist die Einbindung von PV ins Gebäude komplex und erfordert die Anwendung von elektrischer und/oder thermischer Energiespeicherung und entsprechenden Regelstrategien. Dementsprechend ist die Bewertung und Optimierung der Möglichkeit, den PV‐Ertrag direkt im Gebäude zu nutzen oder zu speichern, eine anspruchsvolle Aufgabe. Für eine detaillierte technische Analyse von PV und Energiespeichern auf Gebäudeebene wurden daher umfangreiche Gebäude‐ und Anlagen‐Simulationen anhand von Referenzgebäuden durchgeführt.
MicroRNAs play regulatory roles in genomic balance
Authors: Shi Xiaowen , Yang Hua , Birchler James A. 
Published: December 2022

AbstractClassic genetics studies found that genomic imbalance caused by changing the dosage of part of the genome (aneuploidy) has more detrimental effects than altering the dosage of the whole genome (ploidy). Previous analysis revealed global modulation of gene expression triggered by aneuploidy across various species, including maize (Zea mays), Arabidopsis, yeast, mammals, etc. Plant microRNAs (miRNAs) are a class of 20‐ to 24‐nt endogenous small noncoding RNAs that carry out post‐transcriptional gene expression regulation. That miRNAs and their putative targets are preferentially retained as duplicates after whole‐genome duplication, as are many transcription factors and signaling components, indicates miRNAs are likely to be dosage‐sensitive and potentially involved in genomic balance networks. This review addresses the following questions regarding the role of miRNAs in genomic imbalance. (1) How do aneuploidy and polyploidy impact the expression of miRNAs? (2) Do miRNAs play a regulatory role in modulating the expression of their targets under genomic imbalance?
H2O2 feeding enables LPMO‐assisted cellulose saccharification during simultaneous fermentative production of lactic acid
Authors: Hansen Line D. , Eijsink Vincent G. H. , Horn Svein J. , Várnai Anikó 
Published: December 2022

AbstractSimultaneous saccharification and fermentation (SSF) is a well‐known strategy for valorization of lignocellulosic biomass. Because the fermentation process typically is anaerobic, oxidative enzymes found in modern commercial cellulase cocktails, such as lytic polysaccharide monooxygenases (LPMOs), may be inhibited, limiting the overall efficiency of the enzymatic saccharification. Recent discoveries, however, have shown that LPMOs are active under anoxic conditions if they are provided with H2O2 at low concentrations. In this study, we build on this concept and investigate the potential of using externally added H2O2 to sustain oxidative cellulose depolymerization by LPMOs during an SSF process for lactic acid production. The results of bioreactor experiments with 100 g/L cellulose clearly show that continuous addition of small amounts of H2O2 (at a rate of 80 µM/h) during SSF enables LPMO activity and improves lactic acid production. While further process optimization is needed, the present proof‐of‐concept results show that modern LPMO‐containing cellulase cocktails such as Cellic CTec2 can be used in SSF setups, without sacrificing the LPMO activity in these cocktails.
Nontargeted metabolomics integrated with1H NMR and LC–Q‐TOF–MS/MS methods to depict a more comprehensive metabolic profile in response to chrysosplenetin and artemisinin co‐treatment against artemisinin‐sensitive and ‐resistantPlasmodium bergheiK173
Authors: Wang Yisen , Tian Jingxuan , Chen Jie , Ni Shanhong , Yao Ying , Wang Lirong , Wu Xiuli , Song Ruilong , Chen Jing 
Published: December 2022

AbstractOur previous work revealed mutual and specific metabolites/pathways in artemisinin‐sensitive and ‐resistantPlasmodium bergheiK173‐infected mice. In this study, we further investigated whether chrysosplenetin, a candidate chemical to prevent artemisinin resistance, can regulate these metabolites/pathways by integrating nontargeted metabolomics with1H NMR and LC–Q‐TOF–MS/MS spectrum. The nuclear magnetic resonance method generated specifically altered metabolites in response to co‐treatment with chrysosplenetin, including: the products of glycolysis such as glucose, pyruvate, lactate and alanine; taurine, closely associated with liver injury; arginine and proline as essential amino acids for parasites; TMAO, a biomarker for dysbacteriosis and renal function; and tyrosine, which is used to generate levodopa and dopamine and may improve the torpor state of mice. Importantly, we noticed that chrysosplenetin might depress the activated glycolysis induced by sensitive parasites, but oppositely promoted the inhibited glycolysis to generate more lactate, which suppresses the proliferation of resistant parasites. Moreover, chrysosplentin possibly disturbs the heme biosynthetic pathway in mitochondria. The MS method yielded changed coenzyme A, phosphatidylcholine and ceramides, closely related to mitochondriaβ‐oxidation, cell proliferation, differentiation and apoptosis. These two means shared no overlapped metabolites and formed a more broader metabolic map to study the potential mechanisms of chrysosplenetin as a promising artemisinin resistance inhibitor.
An intriguing case of a paravertebral extramedullary erythropoiesis presenting as tumor‐mimicking lesion in a patient with eosinophilia with FIP1L1‐PDGFRA rearrangement
Authors: Farah Sassi , Yoldez Houcine , Rahma Ayadi , Mona Mlika , Emna Braham , Mahdi Abdennadher , Faouzi El Mezni 
Published: December 2022

AbstractExtramedullary hematopoiesis in the posterior mediastinum is rare. Our case interested a 28‐year‐old man with a history of eosinophilia with FIP1L1‐PDGFRA fusion gene who had a mediastinal mass surgically excised. Pathological examination concluded to an extramedullary erythropoiesis. This case is original by its location and the presence of only the erythroblastic line rearrangement.
Case of laryngeal venous malformations requiring repeated advanced airway management in the perioperative course
Authors: Maruyama Fumi , Masuda Takahiro , Nosaka Nobuyuki , Wakabayashi Kenji 
Published: December 2022

AbstractLaryngeal venous malformations rarely but do cause airway obstruction resulting in life‐threatening events. The perioperative airway management for the patients with them has not been well established. We suggest a strategy for laryngeal venous malformations management in the patients who undergo surgery in addition to planning for airway management.
Cerebral phaeohyphomycosis in liver transplant recipient: A case report
Authors: Ullah Kaleem , Baig Muhammad Asif , Dogar Abdul Wahab , Uddin Shams , Fatir Chaudhary Abdul , Asad Ali , Tahir Muhammad Junaid , Lee Ka Yiu , Mohamed Ahmed Khabab Abbasher Hussien , Yousaf Zohaib 
Published: December 2022

AbstractCerebral phaeohyphomycosis is a fungal brain infection with a high fatality rate. It is caused by dematiaceous fungi and is increasingly recognized as a cause of serious illness in both immunocompetent and immunocompromised patients. We report cerebral phaeohyphomycosis in a liver transplant recipient. He was treated with multiple surgeries and antifungals and made a complete recovery. This report highlights that early and aggressive surgical intervention and extended antifungal coverage can have a positive outcome even in immunocompromised patients. The fungal infection in immunocompromised patients should be considered and treated aggressively.
Rhinogenic optic neuropathy with hemianopia caused by ethmoidal sinus mucocele
Authors: Oka Kosuke , Ando Wataru , Hagiya Hideharu , Higaki Takaya , Otsuka Fumio 
Published: December 2022

AbstractA patient complained of acute right vision loss and headache. A computed tomography scan revealed ethmoidal sinus mucocele in the right ethmoid sinus that was compressing the optic nerve and emergency endoscopic sinus surgery was performed.
Acute myocarditis in a young male after gastroenteritis: A case report and literature review
Authors: Kyaw May Thu , Myint Thein , Lwin Thant Zaw 
Published: December 2022

AbstractA 16‐year‐old patient presented with acute myocarditis after gastroenteritis. His ECGs showed STEMI‐like evolutionary changes. Serial troponin measurement was maximum on 3rd day. Echocardiography showed a mildly reduced ejection fraction (45%). He made an uneventful recovery after appropriate treatment. After one‐month follow‐up, his ECG and echo returned to normal.
Epilepsia Partialis continua secondary to diabetic ketoacidosis
Authors: Sayedahmed Ahmed Mahmoud Sayed , Mohammed Alkhair Ebrahim Abdelrahman Abdelgader , Mohamedali Abdalla Mohamed Abdalla , Mahgoub Mahmoud Saeed Saad 
Published: December 2022

AbstractEpilepsia partialis continua is a rare epileptic syndrome presenting with simple, partial, repetitive motor seizures. It can be a result of structural central nervous system lesion or due to metabolic causes. We report a case of a 65‐year‐old male patient diagnosed with EPC secondary to diabetic ketoacidosis.
Euglycemic diabetic ketoacidosis and COVID‐19 management in a term pregnant patient; a case report
Authors: Mohammadzade Fatemeh , Khodabakhshi Behnaz , Amiri Elahe , Bigdeli Amir , Abdollahi Fahimeh , Fatemi Alireza 
Published: December 2022

AbstractIn this case report, we report a Covid‐19 infected female patient with gestational diabetes mellitus with primary manifestation of ketoacidosis at term pregnancy and discuss the management challenges with euglycemia and a high ketone burden.
Prevalence of coronary artery anomalies in 295 coronary computed tomography angiographies performed in Angola: Challenges and difficulties
Authors: Morais Humberto , Lourenço Preciosa , Martins Carlos , Cardona Lorette , Gonçalves Mauer A. A. 
Published: December 2022

AbstractThe present article describes the prevalence of coronary artery anomalies (CAAs) in patients undergoing coronary CT angiography at a private clinic in Luanda, Angola, and the clinical and angiotomographic characteristics of the two patients with CAAs. These anomalies are uncommon and constitute a significant challenge in resource‐poor countries.
A modified minimally invasive surgery for thoracic pyogenic spondylitis: Percutaneous pedicle screw fixation in combination with a vertebral debridement in a separate posterolateral approach—A case report
Authors: Sato Yuki , Hashimoto Ko , Matsuda Michiharu , Onoki Takahiro , Kamimura Masayuki , Takahashi Kohei , Onoda Yoshito , Chiba Daisuke , Mori Yu , Kanno Haruo , Yamamoto Nobuyuki , Aizawa Toshimi 
Published: December 2022

AbstractIn this report, we present a successfully treated case of intractable thoracic pyogenic spondylitis using one‐step curettage/bone grafting of spinal anterior segment and less‐contaminated percutaneous spinal posterior fixation via separated posterior approaches, which was not compatible with conventional spinal instruments.