bluuebunny/crossref_metadata_2025_split huggingface dataset:
UJI COBA PEMBUATAN KUE SEMPRONG DENGAN TEPUNG SORGUM SEBAGAI SUBSTITUSI TEPUNG BERAS
Authors: Pramudito Pramudito , Rachman Faiza 
Published: November 2022

ABSTRAK Saat ini industri makanan banyak berinovasi, muncul dengan merubah beberapa bahan dasar untuk dijadikan pengganti dapat berupa tepung, gula, susu, ataupun telur. Penelitian ini bertujuan membuat uji coba dengan tepung sorgum sebagai penganti tepung beras, yang menjadi bahan utama dalam pembuatan kue semprong. Jenis penelitian yang digunakan merupakan eksperimen. Pada penelitian ini variabel bebas adalah substitusi tepung sorgum 30%, 60%, dan 90%, sedangkan variabel bebas bersifat organolaptik yang meliputi tekstur dan rasa. Metode pengumpulan data dengan cara menyebarkan kuisioner yang diberikan pada panelis terlatih dan semi terlatih sebanyak 30 orang yang terdiri dari 25 masyarakat biasa dan 5 panelis ahli. Hasil penelitian menunjukkan bahwa dari segi tekstur dan rasa produk kue semprong yang di substitusikan dengan tepung sorgum yang paling disukai dengan perbandingan 30%, dapat merubah rasa dan tekstur asli menjadi lebih enak. Sedangkan dengan perbandingan 60% dan 90%, tidak disukai, karena rasa dan tekstur tidak berubah sama sekali sama seperti aslinya. Jadi dapat disimpulakan bahwa kandungan pada tepung sorgum di dalam pembuatan kue semprong ini berpengaruh terhadap tekstur dan rasa yang berada di dalam kue semprong tersebut. Kata Kunci: Kue Semprong, Rasa, Tekstur, Tepung Sorgum ABSTRACT Currently the food industry is innovating a lot, appearing by changing some basic ingredients to be used as substitutes, which can be flour, sugar, milk, or eggs. This study aims to make trials with sorghum flour as a substitute for rice flour, which is the main ingredient in making semprong cakes. The type of research used is an experiment. In this study, the independent variables were substitution of sorghum flour 30%, 60%, and 90%, while the independent variables were organolaptic which included texture and taste. The data collection method was by distributing questionnaires given to 30 trained and semi-trained panelists consisting of 25 ordinary people and 5 expert panelists. The results showed that in terms of texture and taste, the semprong cake product which was substituted with the most preferred sorghum flour with a ratio of 30%, could change the original taste and texture to be more delicious. Meanwhile, with a ratio of 60% and 90%, it is not liked, because the taste and texture have not changed at all the same as the original. So it can be concluded that the content of sorghum flour in making this semprong cake affects the texture and taste in the semprong cake. Keywords: Flavor, Semprong Cake, Sorghum Flour, Textur
Target cooling options for DARIA compact neutron source
Authors: Moroz Anton R. , Kovalenko Nikita A. , Grigoriev Sergey V. 
Published: November 2022

The extensive heat release in the target is the primary limiting factor for a CANS neutron output. CANS DARIA has been chosen to operate using a 13 MeV proton beam providing up to 40 kW of power, which requires an effective target cooling solution. It was found that beryllium provides the best neutron yield while staying in solid state, which makes it the most effective option for the target material. With an optimal beryllium target thickness of 1.1 mm, the proton Bragg peak lies outside of the beryllium layer, but 9.21 MeV per incident proton are still dissipated inside the beryllium. Two cooling options are considered and analysed with PHITS calculations: multilayer targets and rotating targets. The use of proton beams with energies above 13 MeV on beryllium leads to tritium generation, which is not desirable. Any lower energy leads to a decreased neutron yield, but a simpler cooling solution. Therefore, an option to reduce the proton beam energy is also considered.
ErbB4-encoded novel miRNAs act as tumor suppressors by regulating ErbB/PI3K signaling
Authors: Ghaemi Zahra , Soltani Bahram M. , Mowla Seyed Javad 
Published: November 2022

BACKGROUND: ErbB/PI3K signaling is widely recognized as a critical modulator of malignancy and miRNAs have been found to play a crucial role in the regulation of this pathway. OBJECTIVE: This study aimed to identify novel miRNAs related to the ErbBs loci and investigate the functional effects of these miRNAs on ErbB/PI3K signaling in cancer progression. MATERIALS and METHODS: Bioinformatics tools and RNA-seq data were used to discover novel miRNAs in breast and colon cancer cells. Gene expression levels were determined using RT-qPCR. Western blotting and dual-luciferase assays were used to identify the regulatory mechanism between ErbB4-miR1/2 and related genes. The effects of ErbB4-miR1/2 on cell proliferation, viability, ROS production, and migration were assessed by PI-flow cytometry, colony formation, MTT, ROS, scratch, and transwell assays in SKBR3 and SW480 cells. RESULTS: MicroRNA prediction tools, RNA-seq data, RT-qPCR, and sequencing results identified ErbB4-miR1 and ErbB4-miR2 (ErbB4-miR1/2) as novel miRNAs encoded by ErbB4 gene. ErbB4-miR1/2 were downregulated in breast and colon tumor tissues and also in different cancerous cells. RT-qPCR and dual-luciferase assays revealed that ErbB2 and ErbB3 genes are regulated by ErbB4-miR1/2. Consistently, a decrease in the p-AKT/AKT protein ratio verified the suppressive effect of ErbB4-miR1/2 on ErbB/PI3K activity. Furthermore, ErbB4-miR1/2 overexpression suppressed cell proliferation, viability, and migration, and increased ROS production. CONCLUSIONS: ErbB4-miR1/2 are novel tumor suppressor miRNAs which attenuate ErbB/PI3K signaling in breast and colon cancer cells.
Do PESTLE Factors Impact the Development of Non-oil Manufacturing Companies in Oman?
Authors: Ammal K. Ammani , Al Jassasi Alanoud Rashid Nasser , AlGhafri Sheikha 
Published: November 2022

One of the top priorities of Oman Industrial strategy 2040 is to have economic diversification and activate the role played by manufacturing sector in Oman. As the Oman public finances depend entirely on oil revenues, the development of Oman industrial sector is a key pillar of its long-term development strategy. So the present study aimed to identify and analyse the impact of PESTLE factors on the development of non-oil manufacturing companies in Oman and to suggest suitable measures to develop manufacturing companies in Oman. The researcher used both primary and secondary data for the purpose of the study. The primary data were collected through a structured questionnaire from the sample of 52 manufacturing companies of different sectors in Oman. Further, the researcher had preliminary discussions with the officials of the Department of Commerce, Industry, and Investment Promotion. The collected data were analysed with the help of appropriate statistical tools such as percentage, ANOVA, Independent Z-test, correlation, Regression, and Partial Least Square based Structure Equation Modelling. The results of the study showed that there is a positive relationship between PESTLE factors and the development of non-oil manufacturing companies in Oman.
Recreational Thematic Dominants in News TV Discourse
Authors: Gladko M. A. 
Published: November 2022

Introduction. This study examines the recreational thematic diversity of recreation presented in the form of the thematic dominants list. The thematic dominants are capable of organizing news discourse around themselves and transmitting significant information. Recreation is becoming an integral feature of information discourse, a tool for managing moods and public opinion. That is why the relevance of the topic is determined by the need to study text-forming tools for the implementation of recreation in the discourse. Thematic dominants of recreation are actively involved in the structural organization of the news; implement a wide range of recreational functions. The study of their linguistic implementation rules determines the scientific novelty of the research. The key tasks of the research are to identify the repertoire of thematic dominants of recreation, their functional characteristics, the specifics of participation in the construction of the news text, as well as a description of the recreation scale.Methodology and sources. The study used traditional general scientific methods, such as description and classification of linguistic material, generalization and observation, target sampling, quantitative analysis, as well as linguistic methods: discursive, descriptiveanalytical, contextual, semantic text analysis. As the material of the research, 400 textsrepresentatives of informational TV discourse, various in thematic focus and genre representation, were selected.Results and discussion. The analysis of news discourse allows us to talk about the saturation of recreational topics that broadcast information aimed at providing conditions for rest, relaxation, distraction from everyday problems and entertainment of the addressee. The study reveals macrostructural components, which are most often filled with recreational thematic dominants. It is shown that thematic dominants are unevenly located on the bipolar scale of positive – negative recreation. The extreme, average and threshold degrees of recreation have been established, and the themes that define them have been described.Conclusion. Recreational thematic dominants are aimed at shifting the focus of describing reality for the implementation of recreational functions (the formation of mental effects – distraction, experience; entertainment, interesting leisure, etc.). Their explication represents a multi-layered semiotic system (external level (multimodal resources); internal (macro- and micro-level). Between the two extreme points of recreation there are texts with different levels of recreation, and in descending order the recreational function is combined with additional, non-creative ones.
The Spreading Influence of "Tide of Calligraphy — Itinerant Exhibition for Forty Years of Henan Calligraphy in the New Period"
Authors: Tian Kaifang 
Published: November 2022

The 2019 annual communication and promotion project of the National Art Foundation, "Tide of Calligraphy — Itinerant exhibition for Forty Years of Henan Calligraphy in the New Period", has been completed in Zhengzhou, Changsha, Chengdu, Xi'an and other cities. At present, the COVID-19 epidemic has affected every link of the ecological chain of the exhibition industry, and the work of "Tide of Calligraphy" has also been affected. The epidemic has changed the inherent pattern of exhibition behavior and strongly promoted the development of industries such as "cloud exhibition hall", which provides the public with more aesthetic perspectives and thinking programs. As a beautiful name card of development of Henan calligraphy for 40 years, "Tide of Calligraphy" also adopts the communication method of "cloud exhibition hall" in the exhibition, which stands out from many exhibitions. All of them show their strong cultural communication and influence, which is of great reference value for us to re-examine the exhibition hall mode and the transformation of calligraphy aesthetics under the COVID-19 epidemic.
An Appraisal-based Comparative Study on English and Chinese Movie Review
Authors: Ming Feiqing 
Published: November 2022

With appraisal theory as its theoretical foundation and basing on a self-built small-scaled Chinese and English movie review corpus, the research is conducted from the perspective of types of attitude. Combining qualitative method and quantitative method together, the author tries to make in-depth analyses about the differences of distributions of attitudinal resources in English and Chinese movie reviews. The research concludes that the movie reviewer's culture background will influence their way of using attitudinal resources.
Discussion on Innovation Strategy of Government Management in the New Era
Authors: Yang Muchuan 
Published: November 2022

Government signifies the organization which can be capable of effectively mobilizing social resources and promoting social development in the development of human society. With the improvement of social productivity, further innovation is required for government in management to meet the development needs of the new era, which also leads to a certain lag of government management compared with social development. Government management should be conducted from the following three aspects: system supply, policy incentive and external constraint. At present, there are three problems in government management, such as imperfect system, insufficient information and unqualified staff level. By promoting the holistic level, informationization and professionalism of government services, these three problems can be effectively solved. With the development of productivity, the government management will develop towards the direction of informationization and servitization.
Pengaruh Komunikasi Dan Kerjasama Tim Terhadap Kinerja Pegawai Kecamatan Ilir Barat 1 Palembang
Authors: Taufik Tiara Riska , Hanafi Agustina , Zunaidah Zunaidah , Perizade Badia 
Published: November 2022

Penelitian ini bertujuan untuk menguji Pengaruh Komunikasi Dan Kerjasama Tim Terhadap Kinerja Pegawai Kecamatan Ilir Barat 1 Palembang. Teknik pengambilan sampel dilakukan dengan menggunakan kuesioner. populasi yang diambil yaitu seluruh anggota pegawai Kantor Kecamatan Ilir Barat 1 Palembang yaitu 123 orang. Seluruh populasi dijadikan sampel penelitian. Teknik analisis data dalam penelitian ini menggunakan analisis Regresi Linier Berganda dengan analisis 1) deskriptif kuantitatif; 2) Uji Parsial Variabel (Uji-t); 3) Uji Kesesuaian Model Penelitian (Uji-F); 4) Koefisien Korelasi (r); dan 5) Koefisien Determinasi (). Analisis regresi linear dengan menggunakan software SPSS. Hasil pengujian menunjukkan bahwa 1) Komunikasi dan Kerjasama Tim berpengaruh positif signifikan terhadap Kinerja Pegawai pada Kantor Kecamatan Ilir Barat 1 Palembang; 2) Komunikasi tidak berpengaruh positif dan signifikan terhadap Kinerja Pegawai pada Kantor Kecamatan Ilir Barat 1 Palembang; dan 3) Kerjasama Tim berpengaruh positif yang signifikan terhadap Kinerja Pegawaipada Kantor Kecamatan Ilir Barat 1 Palembang.
Analisis Efektivitas Pelaksanaan Anggaran Aset Tetap Pada Kantor Badan Perencanaan Pembangunan Daerah di Provinsi Sumatera Utara
Authors: K Kamila , Harahap Adillah Sipatussiwa 
Published: November 2022

Value for money harus dipertimbangkan ketika organisasi sektor publik melaksanakan kegiatannya. Pelaksanaan value for money juga harus dapat dipertanggngjawabkan serta memenuhi tujuan yang diinginkan oleh masyarakat, seperti pengadaan serta alokasi sumber daya yang murah, serta keberhasilan atau efektivitas dalam mengapai sasaran atau tujuan. Tujuan penelitian ini adalah untuk menganalisis efektifitas pelaksanaan anggaran belanja pada Aset Tetap BAPPEDA Medan Sumatera Utara. Analisis data yang digunakan analisis deskriptif. Keefektifan pelaksanaan anggaran BAPPEDA Medan Sumut tahun 2019-2021 sangat bervariasi baik tingkat maupun kriterianya. Tahun 2010 menunjukkan tingkat kemanjuran terbesar, sedangkan tahun 2011 menunjukkan tingkat keberhasilan yang paling rendah. Pelaksanaan anggaran tersebut diklaim efektif untuk tahun 20019, 2020, dan 2021, namun masih belum efektif pada tahun 2020 karena anggaran belanja aset tetap jauh dari sasaran. Kesenjangan ini muncul sebagai akibat dari faktor Covid-19 yang muncul di awal tahun; beberapa tindakan yang dianggarkan tidak dilakukan karena lakdawn. Namun, beberapa upaya yang didanai telah terbukti berhasil. Menurut BAPPEDA Medan Sumatera Utara, suatu kegiatan dianggap efektif bila semua tindakan yang dijadwalkan selesai dan dilaksanakan sesuai rencana.
APPLICATION OF PHOTOVOLTAIC SOLAR POWER PLANT TO REDUCE OVER LOAD OF DISTRIBUTION SUBTS COMPLEX YOGYAKARTA CITY HALL ARE
Authors: Dulhadi  , Utama Budi 
Published: November 2022

Kawasan komplek Balai Kota Yogyakarta dipasok listrik PLN 875 KVA dengan arus 3,977 kA, kebutuhan beban maksimal 3,389 kA, sehingga prosentase pembebanan mencapai 85,09 %. Dengan asumsi pertumbuhan beban 1% per tahun dikhawatirkan terjadi kolaps daya listrik, maka perlu penambahan daya listrik agar tidak terjadi kolaps. Potensi sumber daya listrik selain dari PLN yakni pemanfaatan energi baru terbarukan tenaga surya Fotovoltaik. Untuk mengatasi permasalahan tersebut terlebih dahulu dilakukan perencanaan PLTS On Grid. Hasil perencanaan dengan area 1400 m2 didapat daya 204 kWp terdiri 648 panel surya dengan susunan 18 pasangan seri dan 12 paralel. Output tegangan AC pada fase R, S dan T masing – masing 228,63 Volt, 108,2 Ampere. Hasil kontribusi PLTS On Grid dalam bentuk daya AC sebesar 24,74 KVA memberikan tambahan daya 2,8272 %. Penambahan tersebut dapat menghemat biaya operasional sebesar Rp 9.826.300,- per bulan.
Kata kunci: Kolaps, Perencanaan PLTS On Grid, Penghematan
KARAKTERISTIK BATUAN ASAL (BEDROCK) PEMBENTUKAN NIKEL LATERIT PADA DAERAH X DAN SEKITARNYA KABUPATEN MOROWALI UTARA SULAWESI TENGAH
Authors: Biney Andarias , Nugraheni Amara , Kusuma Wijayanti Herning Dyah 
Published: November 2022

Abstract
Administratively, the research area is included in North Morowali Regency, Central Sulawesi Province, Central Java Province, which is in the 49 S zone with UTM (Universal Transverse Mercator) coordinates 9152800 – 9152800 400800 - 406800 mE with an area of ​​± 54 km2 (9 km x 6 km). ). One of the factors that influence the formation of laterite nickel deposits is the source rock. The purpose of this research is to focus on the characteristics of the original rock, namely ultramafic rock based on the intensity of serpentinization, its constituent minerals, and its relation to the laterization potential of nickel deposits in area X and its surroundings, North Morowali Regency, Central Sulawesi. The research method used is literature study, field activities (surface mapping), data processing (laboratory analysis and studio analysis), and report generation. Based on megascopic data, the research area consists of three units, namely alluvial units, peridotite rock units and limestone units. Based on petrographic analysis, the characteristics of the original rock in 10 rock samples were dominated by dunite and followed by serpentinized dunite, harzburgite, lerzolite, wehrlite, and serpentinite. The main mineral compositions in the rock are olivine, clinopyroxene, orthopyroxene, and group serpentine (antigorite, lizardite and talc). Laterite distribution in the research area is dominated by rocky laterite and laterite, with the prospect area being in the eastern part of the study area. The distribution of serpentinization zones based on the intensity level of serpentine minerals in the rock, found in the western hills is dominated by very low-medium serpentinization, while the eastern hills are dominated by low-high serpentinization.
Key words : Origin Rock, Laterite, North Morowali, Petrography, Serpentinization
TESTING OF THE DECISION SUPPORT SYSTEM OF DEPARTMENT DETERMINATION ON HIGH SCHOOL STUDENTS USING BLACK BOX METHOD BASED ON EQUIVALENCE PARTITIONS
Authors: Salsabila Khonsa , Anggraeny Fetty Tri , Rizki Agung Mustika 
Published: November 2022

Pengujian kualitas pada perangkat lunak sangat penting sebelum pengguna menggunakan perangkat lunak tersebut. Pengujian terhadap perangkat lunak diperlukan untuk meminimalisir kerugian yang terjadi akibat kesalahan sistem. Pada penelitian ini yaitu pengujian pada perangkat lunak penentuan jurusan dengan menggunakan Black Box Testing teknik Equivalence Partitions. Teknik Equivalence Partitions ini berfokus pada pengujian dengan menggunakan masukan data pada masing-masing form yang terdapat pada sistem pendukung keputusan penentuan jurusan, setiap form masukan akan dilakukan pengujian dan dikelompokkan berdasarkan fungsinya baik itu sesuai maupun tidak. Hasil dari pengujian dengan menggunakan Black Box Testing berbasis Equivalence Partitions memberikan hasil dimana kita akan mengetahui apakah perangkat lunak ini memiliki kesalah atau tidak, serta pengujian ini dapat menjamin kualitas dari perangkat lunak sistem pendukung keputusan penentuan jurusan ini.
The alterations of circulating mucosal-associated invariant T cells in polycystic ovary syndrome
Authors: Zhou Hong , Xu Junting , Hong Ling , Jia Yanping , Burk Lilo Valerie , Chi Fengli , Zhao Mei , Guan Xiaohong , Liu Dan , Yin Xiangjie , Zhang Yiqiao , Teng Xiaoming , Duan Liyan , Li Kunming 
Published: November 2022

BackgroundPolycystic ovary syndrome (PCOS) is the most common endocrine disorder affecting reproductive age females and an important cause of infertility. Although the etiology is complex and its pathogenesis remains unclear, the pathological process of PCOS is tightly related with the immune dysfunction and gut microbial dysbiosis. Mucosal-associated invariant T (MAIT) cells are a subset of innate-like T cells which can regulate inflammation through the production of cytokines and play a role in regulating the gut microbiota. We aim to evaluate the correlation between characteristics of PCOS and MAIT cells as well as their impact on cytokine secretion.MethodsPeripheral blood samples were taken from PCOS patients (n=33) and healthy controls (n=30) during 2-5 days of the menstrual period. The frequencies of MAIT cells and T cells were measured by flow cytometry. Cytokines interleukin 17 (IL-17), interleukin 22(IL-22), interferon γ (IFN-γ) and granzyme B were determined by Enzyme-linked immunosorbent assay (ELISA).ResultsThe frequency of MAIT cells was significantly reduced in the blood of PCOS patients compared with the controls, and negatively correlated with Body Mass Index (BMI), Homeostatic model assessment- insulin resistance (HOMA-IR) index, and Anti Miillerian Hormone (AMH). Thus, the frequencies of MAIT cells decreased in PCOS patients with abnormal weight (BMI≥24kg/m2), higher HOMA-IR (≥1.5), and excessive AMH (≥8ng/ml). The Cytokine IL-17 was significantly higher in PCOS patients and negatively correlated with the frequency of MAIT cells. Even though the IL-22 was lower in PCOS Patients, no correlation with MAIT cells was detected. In subgroup, CD4+MAIT cells correlated with BMI, AMH, and testosterone (T) levels.ConclusionThe frequency change of MAIT cells may play a significant role in the pathogenesis of PCOS. Exploring these interactions with MAIT cells may provide a new target for PCOS treatment and prevention.
ADAR1-dependent editing regulates human β cell transcriptome diversity during inflammation
Authors: Szymczak Florian , Cohen-Fultheim Roni , Thomaidou Sofia , de Brachène Alexandra Coomans , Castela Angela , Colli Maikel , Marchetti Piero , Levanon Erez , Eizirik Decio , Zaldumbide Arnaud 
Published: November 2022

IntroductionEnterovirus infection has long been suspected as a possible trigger for type 1 diabetes. Upon infection, viral double-stranded RNA (dsRNA) is recognized by membrane and cytosolic sensors that orchestrate type I interferon signaling and the recruitment of innate immune cells to the pancreatic islets. In this context, adenosine deaminase acting on RNA 1 (ADAR1) editing plays an important role in dampening the immune response by inducing adenosine mispairing, destabilizing the RNA duplexes and thus preventing excessive immune activation.MethodsUsing high-throughput RNA sequencing data from human islets and EndoC-βH1 cells exposed to IFNα or IFNγ/IL1β, we evaluated the role of ADAR1 in human pancreatic β cells and determined the impact of the type 1 diabetes pathophysiological environment on ADAR1-dependent RNA editing.ResultsWe show that both IFNα and IFNγ/IL1β stimulation promote ADAR1 expression and increase the A-to-I RNA editing of Alu-Containing mRNAs in EndoC-βH1 cells as well as in primary human islets.DiscussionWe demonstrate that ADAR1 overexpression inhibits type I interferon response signaling, while ADAR1 silencing potentiates IFNα effects. In addition, ADAR1 overexpression triggers the generation of alternatively spliced mRNAs, highlighting a novel role for ADAR1 as a regulator of the β cell transcriptome under inflammatory conditions.