bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of a group‐based exercise and relaxation rehabilitation program during hospitalization for allogeneic hematopoietic stem cell transplant
Authors: Camacho Pérez Encarna , Mayo Samantha , Lipton Jeffrey H. , Chang Eugene , De Souza Lyndsey , Santa Mina Daniel 
Published: February 2022

AbstractBackgroundExercise and relaxation interventions have demonstrated benefits in allogeneic hematopoietic stem cell transplant (allo‐HSCT) patients; however, little is known about the implementation enablers and barriers for inpatient rehabilitation or its impact on health outcomes.ObjectiveTo conduct a program evaluation of group‐based rehabilitation consisting of exercise and relaxation classes for allo‐HSCT inpatients.DesignProspective program evaluation using the RE‐AIM (reach, effectiveness, adoption, implementation, and maintenance) framework.SettingInpatient hospital unit at a tertiary care center.ParticipantsForty‐five adult patients admitted for allo‐HSCT.InterventionsStandard of care rehabilitation.Main Outcome MeasuresProgram attendance, safety, satisfaction, and fidelity were assessed. Exploratory effectiveness analyses were conducted via the measurement of physical, psychosocial, clinical, and health resource use outcomes at hospital admission and discharge.ResultsForty‐seven of the 63 patients receiving allo‐HSCT between November 2019 and March 2020 were consented. Data presented in this publication are from the 33 participants who completed study assessments (high attrition due to cancellation of research during the COVID‐19 pandemic). Eighty‐two percent of participants attended at least one class; however, 55% of the participants invited to the classes on a daily basis were not able to attend. Barriers to participation included transplant complications, isolation for infection prevention, and fatigue. There were no adverse events associated with the intervention and 82% of participants adhered to the prescribed activities. Participants reported satisfaction with the program and enjoyed the motivational support and social interaction. Between hospital admission and discharge, anxiety scores improved; however, fatigue, depression, grip strength, functional mobility, and quality of life scores declined. Physical activity volume and lower body strength were maintained.ConclusionsGroup‐based exercise and relaxation classes seem to be feasible and safe during hospitalization for allo‐HSCT; however, there are pragmatic barriers to be considered for optimal program implementation. Further research examining program effectiveness and adoption is warranted.
On the mechanism of the Au(I)‐mediated addition of alkynes to anthranils to furnish 7‐acylindoles
Authors: Stylianakis Ioannis , Litinas Iraklis , Nieto Faza Olalla , Kolocouris Antonios , Silva López Carlos 
Published: February 2022

AbstractIndole is a very common structural motif in alkaloids with a remarkable history in pharma industry. In the continuous search for more direct and efficient access to these valuable structures, a new and rather elegant approach was found by Jin and coworkers, which involved a gold(I)‐mediated addition of alkynes onto anthralins. This approach selectively furnishes 7‐acylindoles in a rather expeditious way, and it has been shown to be compatible with a large range of decorated reactants, both at the alkyne side and at the anthralin side. We studied the mechanism of this reaction with a set of different alkynes, including disubstituted ones, to establish similarities and differences between them and to aid in the elucidation of key steps in the reaction pathway. The observed regioselectivity seems to be connected to the irreversible formation of a key α‐imino gold carbene intermediate, common to all reaction profiles, through the initial regioselective nucleophilic attack of the anthranil N atom onto the alkyne fragment.
Monitoring multistage multivariate therapeutic processes using risk‐adjusted model‐based group multivariate EWMA control chart
Authors: Rasouli Mohammad , Noorossana Rassoul , Samimi Yaser 
Published: February 2022

AbstractThere exist multitude of therapeutic processes and the results are commonly observed during various dependent steps. For studying such processes that are referred to as multistage therapeutic processes, two concepts are of particular importance; risk adjustment and cascade property. To monitor such processes, a variety of control charts including model‐based control charts are used. In order to design model‐based control charts, analysts must first recognize a suitable model to identify the multistage processes by considering process risks and cascade property. Based on the identified model, the control charts can be proposed. In this study, a risk‐adjusted time‐variant linear state space model is introduced. Afterward, the model order and its parameters are estimated based on Hankel singular value decomposition (HSVD) and prediction error minimization (PEM) methods. Then, the group multivariate exponentially weighted moving average (GMEWMA) control chart is used to monitor a multistage multivariate therapeutic process. To evaluate the performance of the model‐based control chart, a simulation study as well as a two‐stage thyroid cancer surgery was used. Results show that the proposed control chart performs well for predicting and monitoring of multistage multivariate therapeutic processes in real world.
Adaptive neural network control for visual docking of an autonomous underwater vehicle using command filtered backstepping
Authors: Zhang Yuanxu , Gao Jian , Chen Yimin , Bian Chenyi , Zhang Fubin , Liang Qingwei 
Published: February 2022

AbstractThis article proposes an unscented Kalman filter‐based visual docking controller for underactuated underwater vehicles using a position‐based visual servoing (PBVS) approach. The relative pose of an underwater vehicle with respect to a moving docking station is estimated by an unscented Kalman filter with the visual measurements of multiple point features installed on the station. Based on the estimated pose, the Euler angles commands are designed via an integral cross‐tracking docking method to drive the underwater vehicle to move along the desired docking path. Then, an adaptive neural network (NN) controller is designed to track the desired yaw and pitch angles using command filtered backstepping, in which a single‐hidden‐layer (SHL) neural network is employed to compensate for dynamic uncertainties and external disturbances. A barrier Lyapunov function is defined to improve the stability of tracking errors under attitude constraints to ensure the features are in the field of view, and hyperbolic tangent functions are utilized to deal with input saturation. Simulation studies and pool experiments are provided to demonstrate the performances of the proposed visual docking controller.
High‐performance liquid chromatography–ultraviolet detection method to evaluate the migration of di(2‐ethylhexyl) terephthalate and its metabolite from polyvinyl chloride bag in four labile blood products
Authors: Thelliez Aurélie , Descat Amandine , Bouchot Pauline , Kouach Mostafa , Goossens Jean‐François , Decaudin Bertrand , Lecoeur Marie 
Published: February 2022

AbstractA liquid chromatography with UV detection method has been developed and validated for the quantitation of di(2‐ethylhexyl)terephthalate, a blood bag plasticizer, and its monoester metabolite, mono(2‐ethylhexyl)terephthalate, in the four labile blood products: whole blood, red cells concentrate, plasma and platelet concentrate. Quantitation thresholds were compared with those obtained using the more conventional tandem mass spectrometry detection and revealed that UV performed better than mass spectrometry for the quantitation of di(2‐ethylhexyl)terephthalate.Liquid‐liquid extraction was selected for sample preparation. Recoveries ranged from 101 to 106 and from 80 to 83%, for di(2‐ethylhexyl)terephthalate and mono(2‐ethylhexyl)terephthalate, respectively, depending on the labile blood product. Repeatability and intermediate precision expressed as relative standard deviation were lower than 20% at the lower limit of quantitation and ranged from 1.9 to 11.2% for the other concentration levels. Regarding the trueness, bias ranged from ‐13.6 to 11.8%. The method was validated considering a total error of ± 20%. Lower limits of quantitation ranged from 500 to 680 nM for di(2‐ethylhexyl)terephthalate and were equal to 500 nM for mono(2‐ethylhexyl)terephthalate. Migration of di(2‐ethylhexyl)terephthalate from polyvinyl chloride blood bags was investigated and mono(2‐ethylhexyl)terephthalate concentrations were determined in each labile blood product.
Water sources sensitivity: The impacts of forests loss from human activities
Authors: Sweya Lukuba N. , Bumarwa Rashid N. , Igunda Minza Selele 
Published: February 2022

AbstractProper forest management focusing on water resources is crucial for supplying good‐quality freshwater and protecting water sources. However, forests are declining due to urbanization, income generation, and agriculture triggering a potential worry for the sustainability of the water sources. The current study assesses the sensitivity of the water resources in Morogoro, Tanzania through historical forest cover losses. The river discharge and water quality trends are used to complement the assessment and discussions. Forest cover losses are analyzed based on the Sustainable Development Goals’ scale for permanent deforestation. The forest cover loss is increasing linearly and consistently to the discharge trends. Fecal contamination suggests the existence of human settlements in the catchments and that the forests are being invaded. The increasing levels of turbidity indicate that stormwater flows through bare soils carrying foreign materials towards the water sources. The findings create awareness amongst water resources stakeholders regarding the impacts of forest loss on the water supply systems in Morogoro and contribute to an approach for water resources sensitivity assessment that would be applied in other water supply systems.
Corpus callosum abnormality in a puppy with hypernatraemia
Authors: Cridge Harry , Zoto Alyssa , Milne Marjorie E. , Burkland Erica 
Published: February 2022

AbstractA 3‐month‐old, female, entire, mixed breed dog presented for a 1‐day history of ataxia and a 7‐day history of gastrointestinal upset. Neurologic examination revealed dull mentation, head pressing and bruxism. The dog had generalised coarse tremors during ambulation and cervical ventroflexion. Cranial nerve examination, postural reactions and myotatic reflexes were normal. The dog was markedly hypernatraemic at 202 mmol/L (139–151 mmol/L) and was assessed to be non‐hypervolaemic. The dog received custom fluids, and once stabilised, underwent magnetic resonance imaging. Magnetic resonance imaging revealed agenesis of the rostral portion and hypoplasia of the caudal portion of the corpus callosum. Absence of the septum pellucidum and a cortical development abnormality were noted with fusion of the ventral portion of the frontal lobes and malformation of the cingulate gyrus. Cerebrospinal fluid revealed an elevated total protein with a mild lymphocytic and macrophagic pleocytosis. The dog responded well to increased dietary moisture.
Synthesis, characterization, and application of α‐Fe2O3@TiO2@SO3H photo‐Fenton catalyst for photocatalytic degradation of biologically pre‐treated wood industry wastewater
Authors: Azimi Seyyedeh Cobra , Shirini Farhad , Pendashteh Alireza 
Published: February 2022

AbstractThe efficiency of removing chemical oxygen demand (COD) and turbidity from wood wastewater was investigated using a sequencing batch reactor (SBR) and the photo‐Fenton process. A total of 94.78% of COD reduction and 99.9% of turbidity removal were observed under optimum conditions of SBR, which consisted of an organic loading rate (OLR) of 0.453 kg COD m−3 day−1, mixed liquor suspended solids (MLSS) of 4564 mg L−1, and cycle time of 48 h. A magnetic α‐Fe2O3@TiO2@SO3H nanocatalyst was prepared as a heterogeneous Fenton reagent. The Fourier transform infrared (FT‐IR), X‐ray diffraction (XRD), Brunauer–Emmett–Teller (BET), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), energy‐dispersive X‐ray (EDX), and elemental mapping (MAP) analyses were performed to determine the structure and morphology of synthesized photocatalyst. The response surface methodology (RSM) was used to optimize the process based on a central composite design (CCD). The maximum photocatalytic degradation of 87.54% and COD reduction of 83.35% were achieved at a dosage of 0.6 g L−1 of catalyst, 30 mg L−1 of H2O2, and pH of 3.5 for 45 min. The results indicated that a combination of the SBR process and α‐Fe2O3@TiO2@SO3H could be used as an effective method for the treatment of wood wastewater.Practitioner Points
A combination of the SBR and photo‐Fenton process was introduced as an impressive method for wood industry wastewater treatment.
The efficiencies of COD, BOD5, NO3‐N, PO4‐P, and color removal were obtained according to the standard limits in Iran.
To our knowledge, this study is the first report of the use of synthesized α‐Fe2O3@TiO2@SO3H photocatalyst for the wood industry wastewater treatment.
Dancing with Lava: Indigenous Interactions with an Active Volcano in Arizona
Authors: Van Vlack Kathleen 
Published: February 2022

AbstractThe Little Springs Lava Flow is the remnant of an active volcano located in northern Arizona. Southern Paiutes and the scientific community dispute about the Paiute response to this eruption. Paiutes stipulate that this volcano is a ceremonial landscape where religious leaders physically interacted during eruption and subsequently built a series of trails for ceremony. This interpretation contrasts with that of the scientific community, who maintain that volcanoes are dangerous to humans, and therefore Paiutes would have left in fear during the eruption. This chapter explains this debate and how Paiutes are challenging the scientists in order to communicate their environmental heritage.
Quark-gluon backscattering in the Regge limit at one-loop
Authors: Bhattacharya Arindam , Manohar Aneesh V. , Schwartz Matthew D. 
Published: February 2022

Abstract
At small momentum transfer, the quark-gluon scattering cross section dσ/dt has a power-law divergence in the backward scattering region where the outgoing quark is nearly collinear to the incoming gluon. In this Regge limit |t| ≪ s, the leading behavior of the 2 → 2 amplitude can be described by the exchange of Glauber quarks. In Soft-Collinear Effective Theory (SCET) at leading power, Glauber quark exchange is given by five non-local Glauber quark operators, of which only one is generated at tree-level. We show that at leading power the QCD amplitude for quark-gluon backscattering at one-loop can be exactly reproduced by SCET using the tree-level Glauber operator. The agreement between QCD and SCET of the ultraviolet, infrared, and rapidity divergences as well as all logarithms, Glauber phases and finite parts for all polarizations of the external gluons is a strong check on the effective theory. We find that the entire one-loop matching vanishes — there is no correction to the operator generated at tree-level, and the coefficients of the other four operators remain zero at one-loop. This suggests that SCET with Glauber operators may be useful for uncovering new aspects of Regge physics in a systematically improvable way.
Sewing spacetime with Lorentzian threads: complexity and the emergence of time in quantum gravity
Authors: Pedraza Juan F. , Russo Andrea , Svesko Andrew , Weller-Davies Zachary 
Published: February 2022

Abstract
Holographic entanglement entropy was recently recast in terms of Riemannian flows or ‘bit threads’. We consider the Lorentzian analog to reformulate the ‘complexity=volume’ conjecture using Lorentzian flows — timelike vector fields whose minimum flux through a boundary subregion is equal to the volume of the homologous maximal bulk Cauchy slice. By the nesting of Lorentzian flows, holographic complexity is shown to obey a number of properties. Particularly, the rate of complexity is bounded below by conditional complexity, describing a multi-step optimization with intermediate and final target states. We provide multiple explicit geometric realizations of Lorentzian flows in AdS backgrounds, including their time-dependence and behavior near the singularity in a black hole interior. Conceptually, discretized flows are interpreted as Lorentzian threads or ‘gatelines’. Upon selecting a reference state, complexity thence counts the minimum number of gatelines needed to prepare a target state described by a tensor network discretizing the maximal volume slice, matching its quantum information theoretic definition. We point out that suboptimal tensor networks are important to fully characterize the state, leading us to propose a refined notion of complexity as an ensemble average. The bulk symplectic potential provides a specific ‘canonical’ thread configuration characterizing perturbations around arbitrary CFT states. Consistency of this solution requires the bulk satisfy the linearized Einstein’s equations, which are shown to be equivalent to the holographic first law of complexity, thereby advocating for a principle of ‘spacetime complexity’. Lastly, we argue Lorentzian threads provide a notion of emergent time. This article is an expanded and detailed version of [1], including several new results.
On-shell Z boson production at hadron colliders through 𝒪(ααs)
Authors: Bonciani Roberto , Buccioni Federico , Rana Narayan , Vicini Alessandro 
Published: February 2022

Abstract
The analytical expressions of the mixed QCD-EW corrections to on-shell Z boson inclusive production cross section at hadron colliders are presented, together with computational details. The results are given in terms of polylogarithmic functions and elliptic integrals. The impact on the prediction of the Z boson production total cross section is discussed, comparing different proton parton density sets.
Reconstructing Pérez Piñero’s Anoeta Velodrome
Authors: del Blanco García Federico Luis 
Published: February 2022

AbstractThe 1972 dome to cover the Anoeta Velodrome is the product of the experiences up to that date of the architects Emilio Pérez Piñero and Félix Candela, specialists, respectively, in the design of deployable reticular structures and thin concrete shells using hyperbolic paraboloids. It is a very relevant project in the careers of both architects, as the Anoeta dome was Pérez Piñero’s last project, and also the last of the domes in which Candela participated since 1965. Pérez Piñero’s death in 1972 marked the end of a phase in Candela’s life. This paper describes the virtual reconstruction of a variation of the project and analyses its geometry, based on the subdivision of the sphere into polygons onto which hyperbolic paraboloids were then inserted. New documentation is provided which offers context for the evolution of Candela’s work, linking this project to his previous major work: the Palacio de los Deportes built for the 1968 Mexico Olympics.
The diagnostic accuracy of clinical tests for anterior cruciate ligament tears are comparable but the Lachman test has been previously overestimated: a systematic review and meta-analysis
Authors: Sokal Pawel A. , Norris Richard , Maddox Thomas W. , Oldershaw Rachel A. 
Published: February 2022

AbstractPurposeThe diagnostic accuracy of clinical tests for anterior cruciate ligament injury has been reported in previous systematic reviews. Numerous studies in these reviews include subjects with additional knee ligament injury, which could affect the sensitivity of the tests. Meta-analyses have also been performed using methods that do not account for the non-independence of sensitivity and specificity, potentially overestimating diagnostic accuracy. The aim of this study was to report the diagnostic accuracy of clinical tests for anterior cruciate ligament tears (partial and complete) without concomitant knee ligament injury.MethodsA systematic review with meta-analysis was performed according to the PRISMA guidelines. Meta-analyses included studies reporting the specificity and/or sensitivity of tests with or without concomitant meniscal injury. Where possible, pooled diagnostic estimates were calculated with bivariate random-effects modelling to determine the most accurate effect sizes. Diagnostic accuracy values are presented for the anterior drawer, Lachman, Lever sign and pivot shift tests overall and in acute or post-acute presentations.ResultsPooled estimates using a bivariate model for overall sensitivity and specificity respectively were as follows: anterior drawer test 83% [95% CI, 77–88] and 85% [95% CI, 64–95]; Lachman test 81% [95% CI, 73–87] and 85% [95% CI, 73–92]; pivot shift test 55% [95% CI, 47–62] and 94% [95% CI, 88–97]; Lever sign test 83% [95% CI, 68–92] and 91% [95% CI, 83–95]. For specific presentations, the sensitivity and specificity of the Lachman test, respectively, were: complete tears 68% [95% CI, 54–79] and 79% [95% CI, 51–93]; post-acute injuries 70% [95% CI, 57–80] and 77% [95% CI, 53–91].ConclusionsThe pivot shift and Lever sign were the best tests overall for ruling in or ruling out an anterior cruciate ligament tear, respectively. The diagnostic accuracy of the Lachman test, particularly in post-acute presentations and for complete tears, is lower than previously reported. Further research is required to establish more accurate estimates for the Lachman test in acute presentations and partial ligament tears using bivariate analysis.Level of evidenceIII.
Laser pre-structure-assisted micro-milling of Ti6Al4V titanium alloy
Authors: Hojati Faramarz , Azarhoushang Bahman , Daneshi Amir , Biermann Dirk 
Published: February 2022

AbstractHigh flexibility of the micro-milling process compared to nontraditional methods has led to its growing application in manufacturing complex micro-parts with tight tolerances and high accuracies. However, difficulties such as tool deflection, size effect, and tool wear limit the application of micro-milling. In this regard, the role of laser-assisted machining (LAM) is highlighted to prevent mentioned issues through reduction of machining forces and providing the possibility for using higher feeds. Ti6Al4V as a hard-to-machine material is chosen as the workpiece material. Unlike traditional LAM, Ti6Al4V parts were structured using a picosecond laser before micro-milling. The influence of laser structuring at different structure densities on the reduction of machining forces was analyzed at two feeds of 10 and 50 µm/tooth at a constant cutting speed of 35 m/min. A remarkable reduction in cutting forces was observed at both feeds. Additionally, the role of structure density in cutting force reduction is highlighted.