bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Green Chelating Agent and Corrosion Inhibitor on Foam Rheology and Stability at High Temperature, Pressure, and Salinity
Authors: Al-Darweesh Jawad , Aljawad Murtada Saleh , Al-Yousif Zuhair , BinGhanim Ahmed , Kamal Muhammad Shahzad , Mahmoud Mohamed 
Published: November 2022

Summary
This research fills the gap in understanding the impact of corrosion inhibitors (CIs) and a chelating agent on the rheology and stability of foam under harsh conditions. In this regard, a modified high-pressure, high-temperature (HPHT) foam rheometer and HPHT foam analyzer were used to investigate foam rheology and stability at 1,000 psi and 120 to 150°C with carbon dioxide (CO2) in the gas phase. Surfactant screening showed that Duomeen TTM and Armovis are thermally stable at high temperature and high water salinity and thus were used in this study. The liquid phase generally contained produced water (PW) (total dissolved solids ~ 24,611 ppm), 15 wt% chelating agent [L-glutamic acid-N, N-diacetic acid (GLDA)], and 1 wt% surfactant with and without a CI. First, we screened the viscosity and stability of Duomeen TTM and Armovis; the results showed that Duomeen TTM has a higher viscosity (at least by 82%) at a low shear rate, but both have similar viscosity at a higher shear rate. However, Armovis produced more stable foam. Once the GLDA was added to the Duomeen TTM solution, the viscosity increased significantly by 135% at a high shear rate (1,000–1,500). For the Armovis system, the viscosity improved by 77% and 68% at the low and high shear rates by adding GLDA. Additionally, foam stability was improved remarkably in both systems; half-life time almost doubled. Finally, we reported the effect of CI on the fluid systems, showing it considerably reduced the foam viscosity and stability. It reduced the half-life of the Armovis system by 79.4% and hindered the generation of foam for the Duomeen TTM system. A detailed discussion of foam properties, such as foamability, bubble count, and bubble radius, is provided. This study provides a wide-ranging understanding of additives’ impact on stimulating foam stability at HPHT.
BrkgaCuda 2.0: A Framework for Fast Biased Random-Key Genetic Algorithms on GPUs
Authors: de Oliveira Bruno Almêda , Xavier Eduardo Candido , Borin Edson 
Published: November 2022

Abstract

In this paper, we present the development of a new version of the BrkgaCuda, called BrkgaCuda 2.0, to support the design and execution of Biased Random-Key Genetic Algorithms (BRKGA) on CUDA/GPU-enabled computing platforms, employing new techniques to accelerate the execution. We compare the performance of our implementation against the standard CPU implementation called BrkgaAPI, developed by Toso and Resende (2015), and the recently proposed GPU-BRKGA, developed by Alves et al (2021). In the same spirit of the standard implementation, all central aspects of the BRKGA logic are dealt with our framework, and little effort is required to reuse the framework on another problem. The user is also allowed to choose to implement the decoder on the CPU in C++ or on GPU in CUDA. Moreover, the BrkgaCuda provides a decoder that receives a permutation created by sorting the indices of the chromosomes using the genes as keys. To evaluate our framework, we use a total of 54 instances of the Traveling Salesman Problem (TSP), the Set Cover Problem (SCP), and the Capacitated Vehicle Routing Problem (CVRP), using a greedy and an optimal decoder on the CVRP. We show that our framework is faster than the standard BrkgaAPI and the GPU-BRKGA while keeping the same solution quality. Also, when using the bb-segsort to create the permutations, our framework achieves even higher speedups when compared to the others.
Deterministic Bell state measurement with a single quantum memory
Authors: Kosaka Hideo , Kamimaki Akira , Wakamatsu Keidai , Mikata Kosuke , Sekiguchi Yuhei 
Published: November 2022

Abstract
Any quantum information system operates with entanglement as a resource, which should be deterministically generated by a joint measurement known as complete Bell state measurement (BSM). The determinism arises from a quantum nondemolition measurement of two coupled qubits with the help of readout ancilla, which inevitably requires extra physical qubits. We here demonstrate a deterministic and complete BSM with only a nitrogen atom in a nitrogen-vacancy (NV) center in diamond as a quantum memory without reliance on any carbon isotopes by exploiting electron‒nitrogen (14N) double qutrits at a zero magnetic field. The degenerate logical qubits within the subspace of qutrits on the electron and nitrogen spins are holonomically controlled by arbitrarily polarized microwave and radiofrequency pulses via zero-field-split states as the ancilla, enabling the complete BSM deterministically. Since the system works under an isotope-free and field-free environment, the demonstration paves the way for realizing high-yield, high-fidelity, and high-speed quantum repeaters for long-haul quantum networks and quantum interfaces for large-scale distributed quantum computers.
MicroRNAs-26 and related osteogenic target genes can play a pivotal role in improving the mechanical and cellular properties of critical-sized foot defects in photobiomodulation and adipose-derived stem cell-based treatments in a rat model
Authors: Mohebbi Hanieh , Torbati Elham Siasi , Khosravipour Armin , Asghari Mohammadali , Amini Abdollah , Mostafavinia Atarodalsadat , Bayat Mohammad 
Published: November 2022

Abstract
Photobiomodulation (PBM) and stem cell-based treatments are relatively invasive methods for treating bone defects. Specific and oriented cellular and molecular functions can be induced by applying an appropriate type of PBMT and ADSs. This study aimed to explore the role of MicroRNAs in the PBM & hADS-based treatments in improving the mechanical and cellular properties of a critical size fracture in a rat model. A critical size femoral defect (CSFD) is induced in both femoral bones of 24 rats. Then a human demineralized bone matrix scaffold (hDBMS) was engrafted into the CSFDs of all rats. Experiments are performed on 4 groups (12 rats per group): (1) Control (hDBMS); (2) hDBMS + hADS, hADS was engrafted into CSFDs; (3) hDBMS + PBM, the CSFD was exposed to PBM(810 nm wavelength, 1.2 J/cm2 energy density); (4) hDBMS+(hADS + PBM), hADSs were implanted into CSFD then were exposed to PBM. At 42 days after CSFD induction, the rats were killed and, the left and right CSFDs were removed for the mechanical compression tests, and molecular and cellular studies, respectively. The results indicate that miRNA-26a, BMP, SMAD, RUNX, and OSTREX were more expressed in the treated groups than in the control group. Furthermore, the biomechanical and histological properties of CSFDs in treated groups were better than the control group. The correlation tests revealed a positive relationship between microRNA and improving biomechanical and cellular parameters of CSFDs in the rat model. We concluded that MicroRNA-26 plays a significant role in the hADS, PBM, and hADS + PBM-based healing of CSFDs in rats.
Investigating the impact of innovation on Carbon emission: Evidence from OBOR countries
Authors: Mpeqa Rethabile , Sun Hua Ping , Beraud Jean-Jacques Dominique 
Published: November 2022

Abstract
Carbon dioxide emissions are a major cause of global climate change. The public is aware that the world must rapidly reduce its windows to avoid the worst effects of climate change. But how this responsibility is distributed between regions, countries, and individuals has become a recurring element of debate in international debates. This study aimed to compare the different impacts of exporting and importing CO2 emissions in 29 selected countries with the Belt and Road Initiative from 2008 to 2019. We will also look at the impact of innovations on CO2 emissions. Regular testing is done using cross-sectional data, panel data, and integrated testing. Sector results show that exports and imports have a negative effect on CO2 emissions.. EKC is useful in these countries. In addition, population size and energy efficiency increase CO2 emissions. Modern technologies reduce CO2 emissions by increasing energy efficiency. It is important to promote environmental sustainability and the development of professional enterprises in certain countries.
A Randomised Controlled Trial evaluating the Guide Cymru Mental Health Literacy intervention programme in Year 9 (age 13-14) school pupils in Wales
Authors: Simkiss Nicola J. , Gray Nicola S. , Kemp Andrew , Dunne Chris , Snowden Robert J. 
Published: November 2022

Abstract
Background
Adolescent mental health has become a public health concern as 10–20% of adolescents have experiences with mental health problems. Improving mental health education is critical to reducing stigma and improving access to appropriate care when needed. Here we examine the impact of a mental health literacy programme (Guide Cymru) in young adolescents in the UK. A randomised controlled trial assessed the effectiveness of the Guide Cymru intervention.
Method
A total of 1,926 pupils (860 males and 1066 females) aged 13–14 (year 9) took part in the study. The secondary schools were randomised into the active and control arms of the study. Teachers in the active arm of the study were trained on the Guide Cymru and then delivered the intervention to their pupils. Pupils in the active groups received six modules of mental health literacy (the Guide Cymru), and control schools received teaching as usual. Mental health literacy across several domains (e.g., knowledge, stigma, help-seeking intentions) were assessed both before and after the intervention. Data collection for the randomised controlled trial ran from September 2019 to March 2020. Multi-level modelling analysis was conducted to account for the clustered nature of the design.
Results
All aspects of mental health literacy, including mental health knowledge (g = 0.32), good mental health behaviours (g = 0.22), mental health stigmas (g = 0.16), intentions to seek help (g = 0.15), and avoidant coping (g = 0.14) improved after completing the Guide Cymru programme (ps < .001).
Discussion
The current study presents evidence for the Guide Cymru’s effectiveness in improving secondary school pupils' mental health literacy. We demonstrate that providing teachers with appropriate resources and training to deliver the Guide Cymru programme within their classrooms can improve the mental health literacy of pupils. These findings have important implications for the beneficial impacts the secondary school system can have on reducing the burden of mental health problems at a critical point in a young person’s life.
Trial registration
ISRCTN15462041. Registered 03/10/2019.
Angioarchitecture and genetic variants of spinal cord cavernous malformations and associated DVAs — A case report
Authors: Ren Jian , Tu Tianqi , Hong Tao , Zhang Hongqi 
Published: November 2022

Abstract
Cavernous malformations (CMs) have long been considered congenital of central nervous system, while the mechanism of CMs detailed development process associated with genetic factors remains unclear. We reported an uncommon case which suffered spinal cord cavernous malformations. In this work, representative samples were obtained and the sequenced results were described for the first time. A 9-year-old boy was found oblique shoulder with slightly weakness of left limbs, MRI indicated spinal cord cavernous malformations (CMs) located at the C4-C6 vertebral level. On genetic analysis, a shared mutation of PIK3CA (p.H1047R) in CMs and associated DVAs was detected, with a different abundance (2% and 7%, respectively), and a somatic mutation of MAP3K3 (p.I441M) was detected in the CM tissue samples. This case provides better knowledge of the formation history and genetic triggers of the DVA-associated CMs. This evidence allows us to speculate the developmental history of the CM lesion: the DVA with PIK3CA mutation might be genetic precursor, and then the associated CM could be derived from terminal cell population of the DVA by acquiring a somatic mutation in MAP3K3.
Melatonin alleviates chromium toxicity by altering Cr6+ subcellular distribution and enhancing antioxidant metabolism in wheat seedlings
Authors: Sun chuanjiao , Gao Lijun , Xu Libin , Zheng Qiaomei , Sun Shuzhen , Liu Xiaoxue , Zhang Zigang , Tian Zhongwei , Dai Tingbo , Sun Jianyun 
Published: November 2022

Abstract
It was reported that Melatonin (MT) is essential for plants and can mitigate multiple abiotic stresses. However, the mechanism used by endogenous MT to alleviate chromium phytotoxicity is still unclear. In this study, the effects of MT pretreatment on growth, root architecture, subcellular Cr distribution, phytochelatin synthesis and antioxidant metabolism of wheat seedlings under chromium (50 µM Cr6+) stress were researched. Our results showed that Cr stress markedly inhibited seedlings growth and increased ROS accumulation in both roots and leaves. Importantly, growth inhibition and oxidative stress were significantly improved by MT under Cr stress. On the one hand, Cr accumulation and transport from roots to leaves were reduce by MT, which was owed to enhanced vacuolar sequestration via up-regulated phytochelatin (PC) accumulation, which was derived from that MT up-regulated the expression of key genes for PC synthesis (TaPCS and Taγ-ECS). On the other hand, MT pretreatment obviously alleviated Cr-induced oxidative damage, which proved by the diminished lipid peroxidation and cell apoptosis, profiting from the enhanced scavenging ability of reactive oxygen species (ROS) as a result of the MT-induced increment of the activities of superoxide dismutase (SOD), catalase (CAT), ascorbate peroxidase (APX) and glutathione reductase (GR) and the related encoding genes expression levels of TaSOD2, TaCAT, TaAPX and TaGR. Taken together, all these results revealed that MT alleviated Cr toxicity to wheat seedlings probably through altering Cr6+ subcellular distribution and enhancing antioxidant metabolism. And these findings may be helpful to increase wheat production under Cr stress.
TMT-based proteomic analysis of the causes of reduced seed viability in Allium mongolicum under accelerated aging
Authors: Song Xiaoqing , Zhang Dong , Zhang Fenglan , Zhang Xiaoyan , Liu Jiecai , Yang Zhongren 
Published: November 2022

Abstract
Background: Seeds are the most basic production material in agricultural production and occupy an important position in the whole process of agricultural production. However, aging begins to occur after seed harvested, serious aging will affect the conservation of germplasm resources. Seed propagation is the most commonly used method in the production of A.mongolicumseeds, but with the prolongation of storage time, A.mongolicum seeds undergo different degrees of aging. Therefore, we used an integrated approach of Tandem Mass Tag(TMT) labeling in conjunction with liquid chromatographytandem mass spectrometry (LC-MS/MS) to capture the differential protein expression profiles of A.mongolicumseeds under unaged (CK), lightly aged (T1), and severely aged (T4) treatments to provide evidence of protein expression levels for revealing the aging mechanism study of A.mongolicumseeds.
Results: A total of 4336 proteins were identified in this study, of which 4318 total proteins could be quantified. There were 291 diferentially expressed proteins (DEPs) identifed after accelerated aging treatments. Compared with CK, 36 DEPs (16 up-regulated and 20 down-regulated) were found in T1; and 139 DEPs (64 up-regulated and 75 down-regulated) in T4. Compared with T1, 116 DEPs (51 up-regulated and 65 down-regulated) were found in T4. A number of candidate proteins associated with seed aging were screened, for example, ATP-dependent RNA helicase-like protein DB10(Unigene0060546)、β-D-glucan exohydolase(Unigene0008772)、Histone H1.2 partial(Unigene0049278)、defensin Ec-AMP-D2(Unigene0042879)、NAD(P)H dehydrogenase (quinone) FQR1(Unigene0047137)、glutathione S-transferase(Unigene0000863)、oleosin S1-2(Unigene0011542)、probable inactive purple acid phosphatase 2(Unigene0010352)、glutathione S-transferase U8-like(Unigene0006910)、glutathione S-transferase U17-like(Unigene0051938).
Conclusions: This study was the first to determine the proteome of A.mongolicum seeds, these data provided references for further study of seed aging mechanism of A.mongolicum. The results showed that the related proteins were significantly enriched in glutathione metabolism and other pathways after accelerated aging. In addition, among the candidate proteins, PAP2 is down-regulated after aging, which was speculated to be the main reason for limiting radicle growth.
Human Alu elements promote the establishment and enhancement of piRNA-protein-coding gene targeting relationships
Authors: He Chong , Zhu Hao 
Published: November 2022

Abstract
Background: PIWI-interacting RNAs (piRNAs) are the most diverse category of small RNAs in animals. Recent evidence suggests that transposable elements (TEs) incorporated into protein-coding genes (PCGs) can be targeted by piRNAs. Thus, TEs might have a piRNA-mediated influence on organisms. In human PCGs, the extent to which TEs contribute to the presence of piRNA target sites remains to be assessed. Moreover, related evolutionary forces remain to be explored.
Results: We found that the presence of Alu elements, a class of primate-specific TEs, in human PCGs almost always results in potential piRNA target sites. Additionally, we observed that Alu elements can exert a secondary influence on piRNAs and their potential target sites via interlocus gene conversion (IGC). This mutagenic process can homogenize piRNAs and their potential target sites, resulting in an excess of single nucleotide variants (SNVs) that increase piRNA-PCG targeting affinity in the genome. Although Aluelements facilitate the occurrence of SNVs that increase piRNA-PCG targeting affinity, these SNVs tend to show low allele frequencies in the human population. This footprint suggests that natural selection opposes the promotion effect of Alu elements on the formation of piRNA-PCG targeting relationships.
Conclusions: Human Alu elements promote both the establishment and enhancement of piRNA-PCG targeting relationships. In addition, piRNA-PCG targeting relationships impose a piRNA-related selective constraint on the evolution of human PCGs. Our work suggests that the interplay between Alu elements and piRNAs is an important factor that influences the evolutionary trajectory of human PCGs.
Association Between Built Environment on Transport and Recreational Walking in Japan: The Case of Kitakyushu
Authors: Zeng Qian , Bao Xin , Dewancker Bart Julien 
Published: November 2022

Abstract
Walking is a popular form of transportation with a wide range of health, economic, environmental and social benefits. Previous studies have shown that walking is easily influenced by the surrounding built environment. In order to explore the relationship between objective built environment and perceived built environment factors in Japan and transport walking and recreational walking, this study selected Kitakyushu as a sample through questionnaire survey and geographic information data, and evaluated walking activity level through IPAQ and perceive the built environment through ANEWS, and then measured the objective measurement characteristics of the built environment through GIS. Multivariate linear regression model and multivariate logistic model were also used to evaluate the relationship between different built environment factors and pedestrian walking behavior in Japan. The results show that: (1) Age and residential period promoted transport walking. (2) Land mix use, dense bus stops, accessible commercial facilities, and a safe environment can all promote transport walking. (3) High building density and intersection density, more transit stops, more accessible commercial facilities and public service facilities can also promote recreational walking. (4) Having excellent walking facilities increased the time spent on leisure walks.
Surface Water Survey and Localized Waterlogging Risk Assessment in Hanoi, Vietnam
Authors: Nguyen Hong Ngoc , Fukuda Hiroatsu , Nguyen Xuan Hinh 
Published: November 2022

Abstract
This study aims to assess the risk of localized urban waterlogging based on the survey of surface water in the inner city of Hanoi, Vietnam. To achieve this task, the spatial analysis method integrated by ArcGIS, and the open Internet databases were used to generate the contained surface water survey network of Hanoi in 2020. The results show that the natural surface water area has decreased by 37.2% within five years due to urbanization. The area of the artificial lake built up is small and scattered. Achieving data from measurement surveys at 11 vulnerable points for inundation, the author found that there is a significant relationship between the distribution of water-bearing surfaces and the level of waterlogging risk. Congested urban areas that are not connected to surface water are more likely to be vulnerable to inundation. By charting the classification of survey groups according to similar and different characteristics, the analysis is based on indicators to assess the vulnerability of urban inundation to determine the risk of local flooding survey. Finally, this study shows the importance of surface water construction practices in urban inundation risk management and can be used as an example of the current state of the surface survey to contribute to the construction of the basis for urban planning.
Developing Expert International Consensus Statements for Opioid-Sparing Analgesia Using the Delphi Method
Authors: Der Daniel Sng Da , Uitenbosch Giulia , de Boer Hans D. , Carvalho Hugo Nogueira , Cata Juan P , Erdoes Gabor , Heytens Luc , Lois Fernande Jane , Pelosi Paolo , Rousseau Anne-Françoise , Forget Patrice , Nesvadba David 
Published: November 2022

Abstract
Introduction: The management of postoperative pain in anaesthesia is evolving with a deeper understanding of associating multiple modalities and analgesic medications. However, the motivations and barriers regarding the adoption of opioid-sparing analgesia are not well known.
Methods: We designed a modified Delphi survey to explore the perspectives and opinions of expert panellists with regard to opioid-sparing multimodal analgesia. 29 anaesthetists underwent an evolving three-round questionnaire to determine the level of agreement on certain aspects of multimodal analgesia, with the last round deciding if each statement was a priority.
Results: The results were aggregated and a consensus, defined as achievement of over 75% on the Likert scale, was reached for five out of eight statements. The panellists agreed there was a strong body of evidence supporting opioid-sparing multimodal analgesia. However, there existed multiple barriers to widespread adoption, foremost the lack of training and education, as well as the reluctance to change existing practices. Practical issues such as cost effectiveness, increased workload, or the lack of supply of anaesthetic agents were not perceived to be as critical in preventing adoption.
Conclusion: Thus, a focus on developing specific guidelines for multimodal analgesia and addressing gaps in education may improve the adoption of opioid-sparing analgesia.