bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Novel Deep Encrypted Network Traffic Discriminator in Software Defined Network (SDN)
Authors: Mohammadi Negin , Shirmarz Alireza 
Published: September 2022

Abstract
Nowadays, Internet users are rising and need to be supplied with an adoptable quality of service (QoS). Network traffic classification is one of the essential functions that can lead the internet service provider (ISP) to provide required network resources rationally. In facing new flows, the network traffic classification accuracy improvement can play a critical role in network performance, QoS, and security improvement. In this paper, we propose a novel classification model, including (1) a deep autoencoder and (2) a classifier to improve the network traffic classification accuracy in facing new network flows. The deep autoencoder is designed and evaluated in this article with the mean square error (MSE) metric. The proposed deep autoencoder has advanced the model to extract the effective features from the training set more accurately than other methods like the manual method or shallow neural network model. Three distinct classifiers are considered to be added to the deep autoencoder and make it more accurate. The transfer learning is used to add the distinct classifiers, namely logistic regression, random forest, decision tree, and Support Vector Machine (SVM), as a layer to the proposed model. The proposed deep classification model is evaluated with accuracy and f-score measures. The simulation results show that the proposed model has more accuracy and f-score than Convolutional Neural Network (CNN). The UNB ISCX VPN-nonVPN dataset is used for training and testing the model. Software Defined Network (SDN) architecture is used for the proposed model to be deployed because this architecture has made the network more programmable and flexible than the traditional closed networks.
Gender Representations in Biology Textbooks for Secondary Schools in China
Authors: Yang Daihu , Zhou Minghui 
Published: September 2022

Abstract
The gender gap, which is thought to mediate students’ future career trajectory, remains an issue in science education communities over the past decades. Although many factors can contribute to the gender gap in science, textbooks are one of important factors considering their empowering role in shaping students’ attitudes toward gender and projecting their own gender roles in science. How gender is represented in visual matters in biological science textbooks is rarely charted. This study intended to explore the extent to which the illustrations in six biological science textbooks for secondary schools advocate an egalitarian gender ideology by mapping the ratio of female-to-male and enquiring how males and females were rendered through the three dimensions of representational, compositional and interactive meaning of social semiotic theory. The findings reveal that the textbooks appear to be gender neutral at face value since the social semiotic analysis of the individuals in the illustrations suggests that males and females are portrayed impartially. However, the textbooks persist in a sexist ideology through the way in which the quantitative inequality of the two sexes, successful role models and research activities as well as the subtle and nuanced strategies employed by the textbooks to downplay successful female role models and to portray women in more assistant and subordinate roles in professional activities. The gendered message delivered in the textbooks has the potential to disempower female students’ career aspiration and influence their perceptions of their roles in science in relation to their gender.
Menstrual cycle brain plasticity: Ultra-high field 7T MRI reveals changes in human medial temporal lobe volume in female adults
Authors: Zsido Rachel , Williams Angharad , Barth Claudia , Serio Bianca , Kurth Luisa , Beyer Frauke , Witte A. Veronica , Villringer Arno , Sacher Julia 
Published: September 2022

Abstract
Fluctuations in ovarian hormones influence the risk of depression and Alzheimer's disease, which is twice as high in females. How ovarian hormones affect brain structural plasticity in regions involved in memory and affective cognition, however, remains unclear. Detailed menstrual cycle phenotyping in health may therefore allow for differentiating early processes of cognitive decline from normal aging and offer insights into mechanisms contributing to dementia and depression. We performed longitudinal mapping of medial temporal lobe subregion morphology at 6 timepoints across the menstrual cycle in vivo using a dense-sampling protocol, ultra-high field neuroimaging and individually-derived segmentation analysis in 27 healthy participants (19-34 years). We found positive associations between estradiol and parahippocampal cortex volume, progesterone and subiculum and perirhinal Area 35 volumes, and an estradiol*progesterone interaction with CA1 volume. We confirmed volumetric changes were not driven by hormone-related water or blood-flow changes. We provide open access to the data and analytical pipeline. This resource provides a blueprint for examining shared dynamics of the brain and ovarian function to develop sex-specific strategies for identifying and treating brain disorders that affect memory and cognition.
Effects of D and V cryo-plate methods for plum pox virus eradication from two plum cultivars
Authors: Jevremović Darko , Vasilijevic Bojana , Anđelić Tatjana , Vujović Tatjana 
Published: September 2022

AbstractConservation of plant species, particularly of those important for agriculture, has now reached a very high importance in order to ensure sustainable utilization of biological resources by preventing further losses of plant diversity. The most advanced method for plant conservation is cryopreservation. Cryotherapy that relies on cryopreservation procedure, alone or in combination with other techniques, can be used for pathogen elimination from infected plants. Viral diseases pose a significant threat to the agriculture, decreasing yields and crop quality. In this work, two cryotherapy methods (D and V cryo-plate) were evaluated for plum pox virus (PPV) eradication from autochthonous plums ‘Crvena Ranka’ and ‘Belošljiva’, widely present under different local names on the Balkan peninsula. Nine different cryo-plate treatments were performed per each genotype. Cryotherapy was efficient in PPV eradication from plum ‘Crvena Ranka’ in three V cryo-plate treatments, but failed to eliminate PPV from genotype ‘Belošljiva’.
Risk factors and clinical outcomes of extubation failure in very early preterm infants: a single-center cohort study
Authors: Park Su Jeong , Bae Mi Hye , Jeong Mun Hui , Jeong Seong Hee , Lee Na Rae , Byun Shin Yun , Park Kyung Hee 
Published: September 2022

Abstract
Background
Early extubation success (ES) in preterm infants may reduce various mechanical ventilation-associated complications; however, extubation failure (EF) can cause adverse short-term and long-term outcomes. Therefore, the present study aimed to identify the differences in risk factors and clinical outcomes between ES and EF in very early preterm infants.
Methods
This retrospective study was conducted between January 2017 and December 2021. We enrolled premature infants born under the gestational age of 32 weeks who failed extubation even once in the EF group, and patients with similar gestational age and birth weight to the EF group and successful extubation at once were assigned to the ES group. EF was defined as the need for reintubation within 120 hours after extubation. Various variables were analyzed between the two groups.
Results
EF rate in this study was 18.6% (24/129), and approximately 80% of EF patients required re-intubation within 90.17 h. In the ES group, there was less use of inotropes within 7 days of life (12(63.2%) vs. 22(91.7%), p=0.022), a lower respiratory severity score (RSS) at 1 and 4 weeks of age (1.72 vs. 2.5, p=0.026, 1.73 vs. 2.92, p=0.010), and a faster time to reach full feeding (18.7 vs. 29.7, p=0.020). There was a higher severity of BPD (3(15.8%) vs. 14(58.3%), p=0.018), a longer duration of oxygen supply (66.5 vs. 92.9, p=0.042), and higher corrected age at discharge (39.6 vs. 42.5, p=0.043) in the EF group. The cutoff value, sensitivity, and specificity of the RSS at 1 week of age were 1.98, 0.71, and 0.42, respectively, and the cutoff value, sensitivity, and specificity of RSS at 4 weeks of age were 2.22, 0.67, and 0.47, respectively
Conclusions
EF can cause adverse short-term outcomes, such as a higher severity of BPD and a longer duration of hospital days. Therefore, extubation in very early preterm infants should be attempted carefully. The use of inotropes and proceeding feeding and RSS at 1 week of age can be helpful to predict successful extubation.
Study on stability and bearing characteristics of macroscopic pressure arch of surrounding rock in Western deep buried stope of China
Authors: 杨 玉亮 , Zhao Yixin , Zhang Cun , Ma Jianqi , Han Penghua 
Published: September 2022

Abstract
In view of the obvious loose and weak occurrence characteristics of the deeply buried thick weakly cemented stratum in the western mining area of China, the bearing characteristics and stability mechanism of the macrography surrounding rock pressure arch (SRPA) are studied. Firstly, considering the engineering characteristics of deep mining, a SRPA model with trapezoidal load was constructed based on the three-hinged arch theory, the shape characteristic, rise-span ratio and arch thickness equations were derived, the arch thickness under different stress paths is analyzed to characterize the bearing performance of pressure arch. Secondly, the internal force distribution law and destabilization damage type were studied by establishing a two-dimensional bearing SRPA model through arch without articulation theory. The instability type and location can be accurately judged and verified by simulation of similar materials. The results show that, the rational arch axis of SRPA is a cubic parabola with opening downward, its rise-span ratio is between 0.3–0.5. Increasing the rise-span ratio and lateral pressure coefficient can promote the stable bearing capacity of arch. Axial force distribution on the SRPA section is basically consistent with the arch axis, and the arch has the best bearing characteristics. The positive bending moment occurs in the ranges of [0°, 30°] and [81°, 90°] on both sides of the symmetry axis, where is prone to tensile failure. The maximum shear force is concentrated on the arch waist and skewback, and these sections are prone to shear failure. The instability modes of SRPA can be divided into “skewback - vault (arch waist)” and “vault (arch waist) - skewback”. The research results have theoretical guiding significance for mining roof management.
Cytomegalovirus coinfection among people living with HIV in China before and on cART: A retrospective study
Authors: Li Xiaodi , Lu Lianfeng , Liu Xiaosheng , Han Yang , Zhu Ting , Qiu Zhifeng , Li Xiaoxia , Li Yanling , Song Xiaojing , Cao Wei , Li Taisheng 
Published: September 2022

Abstract
Background
Cytomegalovirus (CMV) was the common opportunistic pathogen among people living with HIV(PLWH), even in the combination antiretroviral therapy (ART) era. This study aimed to report the epidemiology and characteristics of CMV coinfection among Chinese PLWH.
Methods
Data were collected from two prospective longitudinal multicenter cohorts of PLWH initiating combination antiretroviral therapy (cART) from 2010 to 2015. This study extracted laboratory parameters, clinical symptoms, and serology of CMV baseline to 192 weeks of cART.
Results
1552 patients were included in this analysis; the prevalence of CMV coinfection was 3.53% before cART. Logistics analysis showed that patients with lower CD4 T cell counts, RPR-seropositive, infected through homosexual contact, and from southern China had a higher risk of CMV/HIV coinfection at baseline. Patients with CMV coinfection at baseline had lower CD4/CD8 ratios at baseline (0.29 vs 0.22, p = 0.006), 96 weeks (0.63 vs 0.51, p = 0.015). After initiation of cART, the incidence of CMV recent infection was 10 cases/1000 PY. Cases coinfected with CMV during cART were mostly asymptomatic and had a comparable CD4, CD8 T cell counts, and CD4/CD8 ratio to non-coinfected patients.
Conclusion
This multicenter study reported a national prevalence and incidence of CMV recent infection among the Chinese PLWH before or on cART. CMV coinfection before cART initiation was associated with a slower recovery of CD4/CD8 ratio. However, CMV coinfection during successful treatment cART seems not to affect immunity parameters.
Association between the Triglyceride to High-Density Lipoprotein Cholesterol Ratio and Mortality in Maintenance Haemodialysis Patients
Authors: Qi LeMuge , Zhang Aihong , Zhang Yanping , Ren Zhuo , Zhao Chen , Wang Qian , Ren Kaiming , Bai Jiuxu , Cao Ning 
Published: September 2022

Abstract
Background
In the general population, TG/HDL-C is as a marker of cardiovascular (CV) events and death. However, studies on TG/HDL-C in haemodialysis (HD) patients are limited, and the results are controversial. This study investigated the TG/HDL-C ratio and all-cause and CV mortality in HD patients.
Methods
In this retrospective cohort study, 582 HD patients were enrolled from June 2015 to September 2016 and followed through September 2021. The outcomes were all-cause death and CV mortality. The optimal threshold for the TG/HDL-C ratio was determined by Youden's index in receiver-operating characteristic curve analyses, and the Kaplan–Meier method and log rank test were applied to assess groups. The association between TG/HDL-C and mortality was analysed by adjusted multivariate Cox proportional hazard regression models.
Results
During the median follow-up of 68 months, 159 patients died, with 82 (51.6%) classified as CV death. The optimal threshold of the TG/HDL-C ratio was determined to be 1.71. Kaplan–Meier curves confirmed that patients with TG/HDL-C ≥1.71 had significantly lower all-cause mortality (log rank test, p = 0.007) and cardiovascular mortality (log rank test, p = 0.006). After adjusting for confounders, multivariate Cox regression analysis showed that TG/HDL-C ≥1.71 was associated with decreased all-cause mortality (adjusted hazard ratio [HR] 0.67, 95% confidence interval [CI] 0.47-0.95, P=0.026) and cardiovascular mortality (adjusted HR: 0.59; 95% CI: 0.36-0.99; P=0.045) in HD patients.
Conclusion
TG/HDL-C is an independent protective factor for mortality in HD patients. High TG/HDL-C was associated with decreased all-cause and CV mortality in HD patients.
Genomic prediction in Brazilian Guzerá cattle: application of a single-step approach to productive and reproductive traits
Authors: Carrara Eula Regina , Peixoto Maria Gabriela Campolina Diniz , Silva Alessandra Alves da , Bruneli Frank Angelo Tomita , Ventura Henrique Torres , Zadra Lenira El Faro , Josahkian Luiz Antônio , Veroneze Renata , Lopes Paulo Sávio 
Published: September 2022

Abstract
This study aimed to investigate the feasibility of genomic prediction for productive and reproductive traits in Guzerá cattle using the single-step genomic BLUP (ssGBLUP). Evaluations included the 305-day cumulative yields (first lactation, in kg) of milk, lactose, protein, fat, and total solids; adjusted body weight (kg) at the ages of 450 days, 365 and 210 days; and age at first calving (in days), from a database containing 197,283 measurements from Guzerá males and females born between 1954 and 2018. The pedigree included 433,823 animals spanning up to 14 overlapping generations. A total of 1,618 animals were genotyped. The analyses were performed using ssGBLUP and traditional BLUP methods. Prediction ability and bias were accessed using cross-validation. The predictive abilities were similar between the methods and ranged from 0.27 to 0.47 for the genomic-based model and from 0.30 to 0.45 for the pedigree-based model. The bias also was similar between the methods, ranging from 0.88 to 1.35 in genomic-based model and from 0.96 to 1.41 in pedigree-based model. The individual accuracy of breeding values had an evident increase in genomic evaluation, with values ranging from 0.41 to 0.56 in the genomic-based model and from 0.26 to 0.54 in the pedigree-based model. Even based on a small number of genotyped animals and a small database for some traits, the results suggest that the ssGBLUP is feasible and may be applied to national genetic evaluations of the breed to increase the accuracy of breeding values, but still without great impact on predictive ability and bias.
YouTube™ as a source of information on prostatitis: A quality and reliability analysis
Authors: Aktas Binhan , Demirel Doruk , Celikkaleli Ferhat , Bulut Suleyman , Ozgur Emrah , Kizilkan Yalcin , Ozden Cuneyt 
Published: September 2022

Abstract
It was aimed to analyze the YouTube™ videos on prostatitis regarding their source, content, and information included. The term “prostatitis” was searched by relevance and the first 200 video links and features were recorded. Using the 5- point modified DISCERN tool, Global Quality Score (GQS), and the Journal of American Medical Association (JAMA) score, quality and reliability of the information were assessed by two urologists. The most common source of upload was doctors/medical institutions (33%), and majority of the content was about general information (27%). The mean modified DISCERN, GQS and JAMA scores were 3.24, 3.25 and 2.17, respectively. These scores were correlated with each other and significantly higher in videos uploaded by doctors/medical institutions. Of the videos, 25.5% were poor, 30.5% were moderate, and 44% were high-quality. High-quality videos were significantly shorter than poor qualities. Poor-quality videos had the highest view ratio. The most of YouTube™ videos on prostatitis are short and high-quality videos uploaded by doctors/medical institutions. However, these videos did not reach the view ratios they deserved.
Self-healing, Solvent-free Anti-corrosion Coating based on Skin-like polyurethane/carbon nanotubes Composite with Real-time Damage Monitoring
Authors: Kong Hui , Luo Xiaomin , Zhang Peng , Feng Jianyan , Li Pengni , Hu Wenjie , Wang Xuechuan , Liu Xinhua 
Published: September 2022

Abstract
Self-healing anti-corrosion coatings are widely regarded as a promising long-term corrosion protection strategy, and it is even more significant if the coating damage can be monitored in real-time and thus repaired. Inspired by the hierarchical structure of human skin, a self-healing solvent-free polyurethane/carbon nanotubes coating (SFPUHE-HTF-CNTs) with a skin-like bilayer structure was constructed by scraping and spraying techniques. The SFPUHE-HTF-CNTs is composed of a self-healing functional layer and a corrosion protection layer. In detail, the hydrophobic solvent-free polyurethane (SFPUHE-HTF) containing disulfide bonds and fluorinated polysiloxane chain segments consists of the self-healing functional layer, and the CNTs with good electrical conductivity consist of the corrosion protection layer, which also allows real-time monitoring of coating damage. SFPUHE-HTF-CNTs can self-repair cracks when heated at 60 ℃ for 16 min or irradiated with UV light at the energy of 200 for 48 h. The results of corrosion protection experiments indicate that the coating has a low corrosion current density (8.94×10− 9 A·cm− 2), a positive corrosion potential (-0.38 V) and a high impedance modulus (|Z|=4.79×105 Ω·cm2). The impedance modulus could still reach 4.54×104 Ω·cm2 after self-healing, showing excellent self-healing properties for anti-corrosion protection. Synchronously, SFPUHE-HTF-CNTs exhibits satisfying damage sensing performance, enabling real-time monitoring of fractures at different sizes. This work realized the effective combination of self-healing performance and corrosion protection and real-time damage monitoring function through bionic design, and completed the simple, green, low-cost and rapid preparation of multi-functional self-healing coating, which has the advantage of scale production.
Adoption and scaling-up of an effective mHealth intervention to increase adherence to triage of HPV-positive women (ATICA study): Perceptions of health decision-makers and health-care providers
Authors: Straw Cecilia , Sanchez-Antelo Victoria , Kohler Racquel , Paolino Melisa , Viswanath Kasisomayajula , Arrossi Silvina 
Published: September 2022

Abstract
Background: The ATICA study was a Hybrid I type randomized effectiveness-implementation trial that demonstrated effectiveness of a multicomponent mHealth intervention (Up to four SMS messages sent to HPV-positive women, and one SMS message to CHWs to prompt a visit of women with no triage Pap 60 days after a positive-test), to increase adherence to triage of HPV positive women (ATICA Study). We report data on perceptions of health decision-makers and healthcare providers regarding the intervention adoption and scaling-up.
Methods: A qualitative study was carried out based on individual, semi-structured interviews with health decision-makers (n=10) and health care providers (n= 10). The themes explored were selected and analyzed using domains and constructs of the Consolidated Framework for Implementation Research (CFIR) and the maintenance dimension of the Reach Effectiveness Adoption Implementation Maintenance (RE-AIM) framework.
Results: Both health care providers and decision-makers had a positive assessment of the intervention through most included constructs: knowledge of the intervention, intervention source, design quality, adaptability, compatibility, access to knowledge and information, relative advantage, women’s needs, and relative priority. However, some potential barriers were also identified including complexity, leadership engagement, external policies, economic cost, women needs and maintenance. Stakeholders conditioned the strategy’s sustainability to the political commitment of national and provincial health authorities to prioritize cervical cancer prevention, and to the establishment of the ATICA strategy as a programmatic line of work by health authorities. They also highlighted the need to ensure, above all, that there is staff to take the Pap tests and carry out the HPV-lab work, and to guarantee a constant provision of HPV-test.
Conclusions: Health decision-makers and healthcare providers had a positive perception regarding implementation of the multicomponent mHealth intervention designed to increase adherence to triage among women with HPV self-collected tests. This increases the potential for a successful scaling-up of the intervention, with great implications for not only to Argentina but also for middle and low-income countries considering using mHealth interventions to enhance the cervical screening/follow-up/treatment process.