bluuebunny/crossref_metadata_2025_split huggingface dataset:
Feasibility and Safety of Whole-Body Electromyostimulation in Frail Older People—A Pilot Trial
Authors: Bloeckl Joerg , Raps Sebastian , Weineck Michael , Kob Robert , Bertsch Thomas , Kemmler Wolfgang , Schoene Daniel 
Published: June 2022

Whole-body electromyostimulation (WB-EMS) induces high-intense stimuli to skeletal muscles with low strain on joints and the autonomic nervous system and may thus be suitable for frail, older people. However, if trained at very high intensities, WB-EMS may damage muscles and kidneys (rhabdomyolysis). This study aimed at investigating the feasibility, safety and preliminary efficacy of WB-EMS in frail, older people. Seven frail (81.3 ± 3.5 years), 11 robust (79.5 ± 3.6 years), 10 young (29.1 ± 6.4 years) participants completed an eight-week WB-EMS training (week 1–4: 1x/week; week 5–8: 1.5x/week) consisting of functional exercises addressing lower extremity strength and balance. Feasibility was assessed using recruitment, adherence, retention, and dropout rates. The satisfaction with WB-EMS was measured using the Physical Activity Enjoyment Scale for older adults (PACES-8). In week 1, 3, and 8 creatine kinase (CK) was assessed immediately before, 48 and 72 h after WB-EMS. Symptoms of rhabdomyolysis (muscle pain, muscle weakness, myoglobinuria) and adverse events were recorded. Functional capacity was assessed at baseline and after 8 weeks using the Short Physical Performance Battery (SPPB), Timed Up-and-Go Test (TUG), Choice Stepping Reaction Time Test (CSRT), 30-second Chair-Stand Test (30-STS), maximum isometric leg strength and handgrip strength. The recruitment rate of frail individuals was 46.2%, adherence 88.3% and the dropout rate 16.7%. All groups indicated a high satisfaction with WB-EMS. CK activity was more pronounced in young individuals with significant changes over time. Within older people CK increased borderline-significantly in the frail group from baseline to week 1 but not afterwards. In robust individuals CK increased significantly from baseline to week 1 and 3. No participant reached CK elevations close to the threshold of ≥5,000 U/l and no symptoms of rhabdomyolysis were observed. With the exception of the TUG (p = 0.173), frail individuals improved in all tests of functional capacity. Compared to the young and robust groups, frail individuals showed the greater improvements in the SPPB, handgrip strength, maximum isokinetic hip-/knee extension and flexion strength. WB-EMS is feasible for frail older people. There were no clinical signs of exertional rhabdomyolysis. WB-EMS proved to be sufficiently intense to induce meaningful changes in functional capacity with frail individuals showing greater improvements for several measures.
Inhibitory Control of Emotional Interference in Deaf Children: Evidence From Event-Related Potentials and Event-Related Spectral Perturbation Analysis
Authors: Chen Qiong , Zhao Junfeng , Gu Huang , Li Xiaoming 
Published: June 2022

BackgroundImpairment of interference control ability may reflect a more general deficit in executive functioning, and lead to an increase in internal-externalized problems such as impulsivity, which has been reported in deaf children. However, few researches have examined the neural mechanism of this impairment.MethodsThis study applied the electroencephalogram (EEG) technique to investigate the interference control ability in 31 deaf children and 28 hearing controls with emotional face-word stroop task.ResultsResults from behavioral task showed that deaf children exhibited lower accuracy compared to hearing controls. As for EEG analysis, reduced activation of ERP components in N1 and enhanced activation of ERP components in N450 have been found in deaf children. Besides, incongruent condition elicited larger N450 than congruent condition. Furthermore, for brain oscillation, alpha band (600–800 ms) revealed a reduced desynchronization in deaf children, while theta band (200–400 ms) revealed an enhanced synchronization in deaf children and incongruent condition, which were in line with ERP components.ConclusionThe present findings seem to indicate that the deficit during emotional interference control ability among deaf children might be due to the impaired attention allocation ability and emotional cognitive monitoring function during emotional conflict detection process. Consequently, reduced N1 and enhanced N450 might be due to early attention impairment causing more effort of deaf children later in emotional cognitive monitoring.
Text Messages in the Field of Mental Health: Rapid Review of the Reviews
Authors: Shalaby Reham , Adu Medard K. , El Gindi Hany M. , Agyapong Vincent I. O. 
Published: June 2022

BackgroundWhile mental health problems constitute a worldwide concern contributing to the global rates of morbidity and mortality, conventional mental healthcare services do not meet the current needs. Text messages (TM) represent a live model that incorporates technology into health services, spanning a large number of health conditions and playing different roles that may support the current healthcare system.ObjectiveTo examine the TM services in the field of mental health, regarding their effectiveness, feasibility, acceptability, and economic evaluation in different contexts of mental health diagnoses and during critical times, when provided to individuals with mental health symptoms/disorders.MethodsThis rapid review was conducted through an online search in PubMed, Embase, PsycINFO, and Medline databases. The review targeted the review studies which examined online or mobile addiction and mental health services, utilizing TM services. The search was run from the inception up to September 30, 2021.ResultsSixty review articles met the inclusion criteria and were included in this review. All reviews were published over the last decade. The results showed that people of a young age were fairly represented, and most reviews were run over substance use disorders (SUD), including Alcohol. Most reviews examined the effectiveness outcomes of the texting service, while to a lesser extent the acceptability and feasibility, among others. Texting services were reported as effective in psychotic disorders and SUD. However, the results related to depression and anxiety were mixed. Most reviews reported a considerably high risk of bias among their included studies. High satisfaction and acceptability of the texting services were reported for patients with various mental health conditions, including those with severe mental illness.ConclusionsThis rapid review highlighted the applications, usability, benefits, and satisfaction with the TM in the field of mental health. For a higher quality of evidence, future studies should consider TM interventions in the contexts with mixed results or a dearth of literature, and during critical times, such as the COVID-19 pandemic. Policy- and decision-makers, therefore, need to further support text-based services with guided investments in interventions that were evidenced to be accepted, economic and feasible.
Strategies For Enhancing Equity, Diversity, and Inclusion in Medical School Admissions–A Canadian Medical School's Journey
Authors: Joy Tisha R. 
Published: June 2022

BackgroundMedical schools aim to select and train future physicians representative of and able to serve their diverse population needs. Enhancing equity, diversity, and inclusion (EDI) in admissions processes includes identifying and mitigating barriers for those underrepresented in medicine (URM).Summary of InnovationsIn 2017, Schulich School of Medicine and Dentistry (Western University, Ontario, Canada) critically reviewed its general Admissions pathways for the Doctor of Medicine (MD) program. Till that time, interview invitations were primarily based on academic metrics rather than a holistic review as for its Indigenous MD Admissions pathway. To help diversify the Canadian physician workforce, Schulich Medicine utilized a multipronged approach with five key changes implemented over 2 years into the general MD Admissions pathways: 1. A voluntary applicant diversity survey (race, socioeconomic status, and community size) to examine potential barriers within the Admissions process; 2. Diversification of the admissions committee and evaluator pool with the inclusion of an Equity Representative on the admissions committee; 3. A biosketch for applicants' life experiences; 4. Implicit bias awareness training for Committee members, file reviewers and interviewers; and 5. A specific pathway for applicants with financial, sociocultural, and medical barriers (termed ACCESS pathway). Diversity data before (Class of 2022) vs. after (Class of 2024) these initiatives and of the applicant pool vs. admitted class were examined.ConclusionFor the Class of 2024, the percentage of admitted racialized students (55.2%), those with socioeconomic challenges (32.3%), and those from remote/rural/small town communities (18.6%) reflected applicant pool demographics (52.8, 29.9, and 17.2%, respectively). Additionally, 5.3% (vs. 5.6% applicant pool) of admitted students had applied through ACCESS. These data suggest that barriers within the admissions process for these URM populations were potentially mitigated by these initiatives. The initiatives broadly improved representation of racialized students, LGBTQ2S+, and those with disability with statistically significant increases in representation of those with socioeconomic challenges (32.3 vs. 19.3%, p = 0.04), and those with language diversity (42.1 vs. 35.0%, p = 0.04). Thus, these changes within the general MD admissions pathways will help diversify the future Canadian physician workforce and inform future initiatives to address health equity and social accountability within Canada.
Association of Habitual Physical Activity With the Risk of All-Cause Mortality Among Chinese Adults: A Prospective Cohort Study
Authors: Hu Peng , Zheng Murui , Huang Jun , Zhao Wenjing , Wang Harry H. X. , Zhang Xiong , Chen Yuanyuan , Deng Hai , Qin Pengzhe , Liu Xudong 
Published: June 2022

ObjectiveThis study was conducted to evaluate the association of the risk of all-cause mortality with habitual physical activity (HPA) and its different domains among Chinese adults.MethodsA total of 11,994 participants from the Guangzhou Heart Study were followed up until 1 January 2020. Information on HPA, including leisure-time physical activity (LTPA) and commute activity, was collected using a modified Global Physical Activity Questionnaire. Individual cause of death was obtained from the National Death Registry of China. Cox proportional hazards regression model was used to estimate hazard ratio (HR) and 95% confidence interval (CI) after adjustment for covariates.ResultsDuring 37,715 person-years of follow-up, 208 deaths (1.73%) were observed. When compared with the highest with the lowest exposure tertiles, HPA and LTPA were associated with 34% (HR: 0.66, 95% CI: 0.46–0.95) and 30% (HR: 0.70, 95% CI: 0.49–0.99) reduced risk of all-cause mortality after adjustment for covariates. Commute activity was not associated with mortality risk. For the specific component of LTPA, we found that every 1 MET-h/week increment of the housework was associated with a 1% (HR: 0.99, 95% CI: 0.98–0.99) decreased mortality risk, and performing brisk walking/health exercises/Yangko was associated with a 46% reduced mortality risk (HR: 0.54, 95% CI: 0.29–0.99).ConclusionThis study suggests that a higher level of HPA and LTPA was associated with a lower risk of all-cause mortality. Our findings suggest people to perform HPA, especially LTPA, as a strategy for mortality reduction and health promotion.
Synchronous Operable Pancreatic and Breast Cancer Without Genetic Mutation: A Literature Review and Discussion
Authors: Ofri Adam , Zuidersma Danika , Diakos Connie I. , Stevanovic Amanda , Wong Matthew , Sood Samriti , Samra Jaswinder S. , Gill Anthony J. , Mittal Anubhav 
Published: June 2022

BackgroundSynchronous cancers are rarely detected when working-up a patient for a primary cancer. Neoadjuvant management of synchronous breast and pancreatic cancers, without a germline mutation, has yet to be discussed. Two patients were diagnosed with synchronous breast and pancreatic cancers at our institution over the last decade. A literature review was performed to evaluate the current evidence stance.ResultsThe first patient was 61-years old and diagnosed with a HER2+ breast cancer. The second patient was 77-years old and diagnosed with a Luminal B breast cancer. The inability to provide concurrent breast and pancreatic neoadjuvant therapy for the HER2+ patient, resulted in upfront surgery. The second patient was able to have both cancers treated simultaneously - neoadjuvant chemotherapy to the pancreas, and neoadjuvant endocrine therapy to the breast.DiscussThere is no single neoadjuvant regimen that treats both pancreatic and breast cancer. The differences in breast cancer sub-types impacted our neoadjuvant options. Our recent experience led us to the hypothesis that breast cancer care dictates treatment, while pancreatic cancer determines survival. There is a significant paucity in the literature regarding synchronous breast and pancreatic cancer.
Radially Symmetric Solution for Fractional Laplacian Systems with Different Negative Powers
Authors: Xu Haiyong , Ahmad Bashir , Wang Guotao , Zhang Lihong 
Published: June 2022

By developing the direct method of moving planes, we study the radial symmetry of nonnegative solutions for a fractional Laplacian system with different negative powers: (−Δ)α2u(x)+u−γ(x)+v−q(x)=0,x∈RN, (−Δ)β2v(x)+v−σ(x)+u−p(x)=0,x∈RN, u(x)≳|x|a,v(x)≳|x|bas|x|→∞, where α,β∈(0,2), and a,b>0 are constants. We study the decay at infinity and narrow region principle for the fractional Laplacian system with different negative powers. The same results hold for nonlinear Hénon-type fractional Laplacian systems with different negative powers.
Predictors for inappropriate proton pump inhibitor use: observational study in primary care
Authors: Koggel Lieke Maria , Lantinga Marten Alexander , Büchner Frederike Leonie , Drenth Joost Paulus Hubertus , Frankema Jacqueline Sarah , Heeregrave Edwin Johannes , Heringa Mette , Numans Mattijs Everard , Siersema Peter Derk 
Published: June 2022

BackgroundProton pump inhibitor (PPI) indications are limited to gastrointestinal disorders and ulcer prophylaxis. However, PPIs are among the most frequently prescribed drugs.AimTo evaluate the appropriateness of PPI prescriptions and identify predictive factors for inappropriate PPI use.Design and settingObservational study using a Dutch primary care database with all new PPI prescriptions between 2016 and 2018.MethodIndividual patient data and details on PPI use were collected. The appropriateness of initiation and continuation of PPI prescriptions was evaluated using the applicable guidelines.ResultsIn total, 148 926 patients (aged ≥18 years) from 27 general practices were evaluated. A total of 23 601 (16%) patients started PPI therapy (mean age 57 [SD 17] years, 59% female). Valid PPI indications at initiation were seen in 10 466 PPI users (44%). Predictors for inappropriately initiated PPI use were older age (odds ratio [OR] 1.03, 95% confidence interval [CI] = 1.03 to 1.03), and use of non-selective non-steroidal anti-inflammatory drugs (OR 5.15, 95% CI = 4.70 to 5.65), adenosine diphosphate receptor inhibitors (OR 5.07, 95% CI = 3.46 to 7.41), COX-2 inhibitors (also known as coxibs) (OR 3.93, 95% CI = 2.92 to 5.28), and low-dose aspirin (OR 3.83, 95% CI = 3.07 to 4.77). Despite an initial valid indication, PPI use was inaccurately continued in 32% of patients on short-course therapy for dyspepsia and in 11% of patients on ulcer prophylaxis.ConclusionMore than half of PPI users in primary care were found to have an inappropriate indication, with unnecessary ulcer prophylaxis related to drug use being one of the leading causes. Future initiatives to reduce PPI use for unnecessary ulcer prophylaxis and timely deprescription if PPI is no longer indicated, are needed.
Comparison of operational costs and production of fresh tuna products; before and during the Covid-19 pandemic in Talaud Islands Regency, North Sulawesi Province
Authors: Naung Pelia , Luasunaung Alfret , Andaki Jardie A. , Suhaeni Siti , Kaligis Erly Y. , Manembu Indri S. 
Published: June 2022

Covid-19 pandemic has implications for all aspects of fishery activities in Indonesia, one of them is negative impact on the supply chain of the fishery business. To find out more about this impact, the study was aimed to determine the condition, in general, of tuna capture fisheries in the Talaud Islands Regency before and during the Covid-19 Pandemic, and to find out the comparison of operational costs and production of fresh tuna at the level of fishermen and intermediary traders in the area in both periods. Data collection was carried out in April 2020 to March 2021. Three districts in the area were selected as research locations, namely Salibabu, Gemeh, and South Essang. Surveys using questionnaires were conducted on respondents at predetermined locations. Comparative analysis using t-test was applied in this study. The results showed that the pandemic has caused, among other things, a decline in fish prices, effect in community's economy, and a decrease of tuna production. Tuna production is particularly important because while it affected the production, the operational costs remained constant. This occurs at all levels, both at the level of fishermen and at the level of intermediary traders. It can be concluded that the Covid-19 pandemic has had an impact on fresh tuna fishing activities in the area where fresh tuna production has decreased and tuna buying traders are not operating. In particular, the operational costs of catching tuna at the fisherman's level are the same, both before and during the pandemic. Meanwhile, tuna production has decreased dramatically during the pandemic. This also happens at the level of intermediary traders.Indonesian title: Komparasi biaya operasional dan produksi produk tuna segar pada masa sebelum dan selama Pandemi Covid-19 di Kabupaten Kepulauan Talaud, Provinsi Sulawesi Utara
Coastal tourism development of Diyonumo Island, East Sumalata District, Gorontalo-Indonesia, based on natural resources and carrying capacity
Authors: Kamah Masita H. , Sahami Femy M. , Baruadi Alfi S. 
Published: June 2022

The purpose of this study is to assess the suitability of coastal tourism in the Diyonumo Island and the carrying capacity of the area to support the sustainability development of coastal tourism in the island. The study was conducted at Diyonumo Island, Deme II Village, East Sumalata District, North Gorontalo District, Gorontalo Province, from September to November 2020. The data collection was done by observation and surveys. Study location was divided into 4 stations with an assessment of 3 categories designated for beach tourism, namely recreation, fishing, and camping. Tourism Suitability Index (TSI) and carrying capacity were calculated from the obtained data. The results showed that the island has the potential to be developed into a tourist area with the TSI value for the categories of recreational, fishing, and camping is categorised ‘very suitable’. Moreover, the carryingcapacity for recreation, fishing, and camping are 1.916 people/day, 104 people/day, and 125 people/day, respectively. The most important thing to do in order to achieve a sustainable development and management is by properly use and manage the resource of the island and this effort can be done by government through community empowerment programs.Indonesian title: Pengembangan wisata pantai berbasis potensi dan daya dukung kawasan Pulau Diyonumo, Kecamatan Sumalata Timur, Gorontalo-Indonesia
Heteroepitaxial growth of InSb thin film on SrTiO3 (001) by pulsed laser deposition for magnetic Hall sensor application
Authors: Lee Koomok , Shigematsu Kei , Azuma Masaki 
Published: June 2022

Abstract
Ⅲ–Ⅴ semiconductor compound InSb with a zinc blende structure and extremely high electron mobility was grown as a thin film on SrTiO3 (STO)(001) substrate by pulsed laser deposition. The growth of (111) oriented InSb was observed despite a large lattice mismatch of 1.6% ([1−10]InSb ∣∣ [010]STO) and 17.8% ([11−2]InSb ∣∣ [100]STO). Electron mobility of 94 cm2 V−1s−1 at room temperature was confirmed by Hall effect measurement and the magnetic field reversal down to 1 Oe was detected. Growth of InSb/STO (001) thin film could be a promising approach for the detection of magnetic signals from various perovskite type functional oxide materials and will find applications in future devices.
Effect of Au electrode on the resistance change response of HfO
x
-based ReRAM device under voltage pulse trains
Authors: Shingubara S. , Huang C.Y. , Hatanaka R. , Shimizu T. , Ito T. 
Published: June 2022

Abstract
The demand for neuromorphic computing is increasing, and resistive random access memory (ReRAM) devices are intriguing candidates for synaptic applications. We studied a Ti/HfO
x
/Au ReRAM device with this potential in view, and fabricated a Ti/HfO
x
/Pt device for comparison. Both devices exhibited bipolar switching characteristics. In response to voltage pulse trains, gradual resistance change was observed in the Ti/HfO
x
/Au device for both the SET and RESET processes, indicating its suitability for artificial synapse application. In contrast, an abrupt resistance change was observed in the SET process of the Ti/HfO
x
/Pt device. A significant diffusion of Au atoms occurred in the HfO
x
layer of the Ti/HfO
x
/Au device, and the Au atoms were oxidized at the interface. This led to an increase in the O vacancy concentration, which assisted the achievement of the gradual resistance change. The present study indicates that the Ti/HfO
x
/Au device demonstrates good potential for use as an artificial synaptic device.
Aufzüge lernen von der Gebäudetechnik
Authors: Stricker-Berghoff Undine 
Published: June 2022

39. Heilbronner Aufzugstage

Ein umfangreiches Hygienekonzept machte es möglich, dass die 39. Heilbronner Aufzugstage Anfang März bereits wieder als Präsenzveranstaltung stattfinden konnten. In der Harmonie Heilbronn standen die Themen Nachhaltigkeit, Digitalisierung und Regelwerke im Mittelpunkt. Die zunehmende Verflechtung der Gebäudetechnik mit dem noch sehr geschlossenen Gewerk Aufzugstechnik zeigte sich auf dieser Tagung verstärkt.
PENINGKATAN PENDAPATAN PEREKONOMIAN KELUARGA MELALUI “PEJUANG SUBUH” DI PONDOK BENOWO INDAH SURABAYA DALAM ERA PANDEMI COVID 19
Authors: Dewianawati Dwi , Setiawan Erry 
Published: June 2022

Dalam menghadapi era COVID 19 banyak warga yang mengalami penurunan pendapatan, bahkan banyak pula yang sudah tidak berpenghasilan, mereka tergabung dalam kelompok “Pejuang Subuh”yang berlokasi di Pondok benowo Indah Surabaya dimana dengan peran para perempuan atau ibu ibu bertujuan meningkatkan pendapatan perekonomian keluarga dengan mengembangkan kemampuan para perempuan dalam bidang kuliner baik kue kue maupun makanan.
Peneletian ini dilakukan dengana analisa menggunakana analisa Kualitatif dimana saat pengumpulan data berlangsung dan setelah selesai pengumpulan data dan periode tertentu. Kegiatan dilaksanakan dengan wawancara interaktif dan dilakukan secara terus menerus sampai selesai sehingga datanya sampai jenuh. Kegiatan pengolahan data menggunakan data reduction, data display, dan conculusion drawing/ purification
Hasil penelitian yang dapat di berikan adalah Berhasilnya pemberdayaan perempuan pada penelitian ini tergantung pada kerjasama antar individu, yang dalam penelitian ini kerjasama antar pengurus, anggota dan pendamping. Pengaruh pendamping memiliki peran besar terhadap kesuksesan pemberdayaan masyarakat pada penelitian ini. Pengembangan potensi baik pada setiap individu dalam kelompok Pejuang Subuh ini menjadi salah satu faktor yang menghasilkan produk maknan atau kue yang kreatif dan inovatif sehingga dengan ini, memiliki ciri khas tersendiri dibandingkan dengan pesaing lainnya. Harapan pada penelitian ini kedepan diadakan pembinaan, baik secara pelatihan ataupun workshop mengenai produks yang bagus dan pengelolaan keuangan.