bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk Factors for Heart Failure Among Pan-European Childhood Cancer Survivors: A PanCareSurFup and ProCardio Cohort and Nested Case-Control Study
Authors: de Baat Esmée C. , Feijen Elizabeth A.M. , Reulen Raoul C. , Allodji Rodrigue S. , Bagnasco Francesca , Bardi Edit , Belle Fabiën N. , Byrne Julianne , van Dalen Elvira C. , Debiche Ghazi , Diallo Ibrahima , Grabow Desiree , Hjorth Lars , Jankovic Momcilo , Kuehni Claudia E. , Levitt Gill , Llanas Damien , Loonen Jacqueline , Zaletel Lorna Z. , Maule Milena M. , Miligi Lucia , van der Pal Helena J.H. , Ronckers Cécile M. , Sacerdote Carlotta , Skinner Roderick , Jakab Zsuzsanna , Veres Cristina , Haddy Nadia , Winter David L. , de Vathaire Florent , Hawkins Michael M. , Kremer Leontien C.M. 
Published: September 2022

PURPOSE Heart failure (HF) is a potentially life-threatening complication of treatment for childhood cancer. We evaluated the risk and risk factors for HF in a large European study of long-term survivors. Little is known of the effects of low doses of treatment, which is needed to improve current treatment protocols and surveillance guidelines. METHODS This study includes the PanCareSurFup and ProCardio cohort of ≥ 5-year childhood cancer survivors diagnosed between 1940 and 2009 in seven European countries (N = 42,361). We calculated the cumulative incidence of HF and conducted a nested case-control study to evaluate detailed treatment-related risk factors. RESULTS The cumulative incidence of HF was 2% (95% CI, 1.7 to 2.2) by age 50 years. The case-control study (n = 1,000) showed that survivors who received a mean heart radiation therapy (RT) dose of 5 to < 15 Gy have an increased risk of HF (odds ratio, 5.5; 95% CI, 2.5 to 12.3), when compared with no heart RT. The risk associated with doses 5 to < 15 Gy increased with exposure of a larger heart volume. In addition, the HF risk increased in a linear fashion with higher mean heart RT doses. Regarding total cumulative anthracycline dose, survivors who received ≥ 100 mg/m2 had a substantially increased risk of HF and survivors treated with a lower dose showed no significantly increased risk of HF. The dose-response relationship appeared quadratic with higher anthracycline doses. CONCLUSION Survivors who received a mean heart RT dose of ≥ 5 Gy have an increased risk of HF. The risk associated with RT increases with larger volumes exposed. Survivors treated with < 100 mg/m2 total cumulative anthracycline dose have no significantly increased risk of HF. These new findings might have consequences for new treatment protocols for children with cancer and for cardiomyopathy surveillance guidelines.
Machine learning with different digital images classification in laparoscopic surgery
Authors: Bayazitov M. , Liashenko A. , Bayazitov D. , Stoeva T. , Godlevska T. 
Published: September 2022

The evaluation of the effectiveness of the automatic computer diagnostic (ACD) systems developed based on two classifiers – HAAR features cascade and AdaBoost for the laparoscopic diagnostics of appendicitis and ovarian cysts in women with chronic pelvic pain is presented. The training of HAAR features cascade, and AdaBoost classifiers were performed with images/ frames, which have been extracted from video gained in laparoscopic diagnostics. Both gamma-corrected RGB and RGB converted into HSV frames were used for training. Descriptors were extracted from images with the method of Local Binary Pattern (LBP), which includes both data on color characteristics («modified color LBP» - MCLBP) and textural characteristics, which have been used later on for AdaBoost classifier training. Classification of test video images revealed that the highest recall for appendicitis diagnostics was achieved after training of AdaBoost with MCLBP descriptors extracted from RGB images – 0.708, and in the case of ovarian cysts diagnostics – for MCLBP gained from RGB images – 0.886.
Developed AdaBoost-based ACD system achieved a 73.6% correct classification rate (accuracy) for appendicitis and 85.4% for ovarian cysts. The accuracy of the HAAR features classifier was highest in the case of ovarian cysts identification and achieved 0.653 (RGB) – 0.708 (HSV) values. It was concluded that the HAAR feature-based cascade classifier turned to be less effective when compared with the AdaBoost classifier trained with MCLBP descriptors. Ovarian cysts were better diagnosed when compared with appendicitis with the developed ACD.
Białoruska poezja protestu. Symbole, emocje i kontekst
Authors: Monina Vera , Weżgowiec Barbara 
Published: September 2022

BELARUSIAN PROTEST POETRY: SYMBOLS, EMOTIONS AND CONTEXT
The article discusses protest poetry written by Belarusians poets after the rigged elections on August 9, 2020 and during the so-called “Belarusian revolution”. Using the example of three poems in Russian, Belarusian and Polish, the paper tries to deconstruct the meaning of symbols actively used in protest poetry and also sketches the context in which these symbols exist. Poetry in the article is also considered as a way of expressing emotions at various structural levels.
Acute Recurrent Pericarditis as the Inaugural Manifestation of Familial Mediterranean Fever
Authors: Hassene Attout , Amichi Sofia , Bouhamla Hichem 
Published: September 2022

Familial Mediterranean fever (FMF) is an inherited autosomal recessive disorder commonly found among individuals of Mediterranean or Middle Eastern descent and caused by Mediterranean Fever gene (MEFV) mutations on chromosome 16. It is the most frequent periodic febrile syndrome among the autoinflammatory syndromes. Typical febrile attacks include serosal inflammation, but although FMF is characterized by recurrent polyserositis, there is a little documentation of pericardial disease among patients. We report the case of a patient who presented recurrent pericarditis. Each episode occurred with a high fever and elevation of the C-reactive protein level. Treatment with colchicine was effective. The patient was found to be heterozygous for the V726A mutation.
Doe and kid activity in the first hours of life
Authors: Cooper Yasmine , Anzuino Katherine 
Published: September 2022

Background: Currently there is little to no published data describing the behaviours of does and kids on UK dairy farms immediately following parturition. Aims: This small study explored behaviour expressed by does and kids in the period immediately following parturition and tentatively identified potential areas for future study of goat behaviour in UK dairy systems. It aimed to develop an ethogram and trial this ethogram by recording activities of kids and their does in the first hours following parturition on a UK dairy goat farm. Methods: Five does were each observed for a period of 248 minutes, alongside their 10 kids. Observations began shortly after does were confined in pens with their kids and the kids had been fed colostrum via stomach tube. Doe and kid activities were recorded at 2-minute intervals. Results: The most prevalent activities observed in kids were ‘lying down’ and ‘searching for a teat’. The most prevalent activities observed in does were ‘grooming’ and ‘standing neutrally’. Does spent most of the first hours of the kids’ life grooming, then feeding and lying down later. Kids started searching for a teat within 1 hour after being fed colostrum by stomach tube but took much longer to successfully suckle. Conclusion: The ethogram proved practical to use, and lessons learned from this trial could be used to develop further behavioural studies.
Eugenia uniflora L. seedling production by cutting: substrate, sazonality, auxine and rejuvenation methods
Authors: Cipriano Roger , Tomazzoli Maíra Maciel , Tofanelli Mauro Brasil Dias , Santos Bruno Francisco Sant’Anna , Ribas Katia Christina Zuffellato , Deschamps Cícero 
Published: September 2022

Eugenia uniflora is a species that presents great phytochemical variability, due to its main form of propagation, the seminal, which makes the cultivation of this commercial crop unfeasible. Therefore, the objective of this work was to develop a protocol for vegetative propagation of Eugenia uniflora by stem cuttings. Substrates (Tropstrato®, vermiculite and sand), indolbutyric acid concentrations, rejuvenation methods (drastic pruning and minicutting) and harvesting times (winter, summer, autumn and winter) of the stems were compared. The highest rooting percentage and quality of the root system in cuttings were obtained when commercial substrate Tropstrato® and with some method of rejuvenation were used. The minicutting was more efficient, reaching almost 50% of rooting when collected in summer . Stem cuttings from plants that did not undergo any kind of rejuvenation, regardless of the time of collection, did not result in root formation. No anatomical changes were observed between cuttings from rejuvenated and non-rejuvenated plant material, indicating that the rhizogenic process did not occur in the cuttings originated from plants without rejuvenation because of biochemical and/or physiological reasons. The treatment of the stem cuttings with IBA did not result in increase of rooting, therefore the use of this plant regulator is not recommended.
Hydrogen peroxide as a mitigator of salt stress for melon seed germination
Authors: Rocha Limão Marcelo Augusto , Batista Silva Rodrigues Marília Hortência , Da Silva Santos Adriana , Silva Barbosa Luana , Pinheiro Lopes Kilson , Cunha Fernandes dos Santos Dias Denise 
Published: September 2022

O efeito do peróxido de hidrogênio vem sendo muito estudado, mas pouco se sabe sobre o seu efeito na germinação e crescimento inicial de sementes de meloeiro submetidas ao estresse salino. Neste contexto, objetivou-se avaliar o efeito do peróxido de hidrogênio como atenuante do estresse salino na germinação das sementes de meloeiro. O trabalho foi realizado no Laboratório de Sementes e Mudas da Universidade Federal de Campina Grande, campus Pombal-PB. O experimento foi conduzido em delineamento inteiramente casualizado, em esquema fatorial 4 x 6, tempos de embebição no H 2 O 2 (TE 1 : 0; TE 2 : 8; TE 3 : 16 e TE 4: 24 horas) e níveis de salinidade da água de irrigação (0,3; 1,2; 2,1; 3,0; 3,9 e 4,8 dS m -1 ), com quatro repetições. Foram utilizadas sementes de meloeiro da variedade comercial Imperial-45. A solução foi preparada a partir de uma solução a 1mmol L -1 de H 2 O 2 , sendo diluída para atingir a concentração de 10 µmol L -1 , posteriormente como sementes foram acondicionadas em becker e embebidas com 100 ml da solução por diferentes tempos . As variáveis ​​avaliadas foram: porcentagem de germinação, primeira contagem de germinação, índice de velocidade de germinação, velocidade média de germinação, tempo médio de germinação e comprimento da radícula. Sementes embebidas em solução de H 2 O2 por 16 horas atenuam os efeitos causados ​​pelo estresse salino em até 2,2 dS m -1 , porém quando embebidas por 24 horas na solução de H 2 O 2 causaram prejuízos no processo germinativo das sementes meloeiro.
Evaluation of residual strength of polymeric yarns subjected to previous impact loads
Authors: Hahn Gabriela , Monteiro da Fonseca Thomé da Silva Antônio Henrique , Tempel Stumpf Felipe , Marcos Guilherme Carlos Eduardo 
Published: September 2022

The discovery of oil fields in deep and ultra-deep waters provided an opportunity to evaluate the use of synthetic ropes, complementarily or alternatively to traditional steel-based mooring lines in offshore units, mainly because of the former’s lower specific weight. Considering the series of complex dynamic-mechanical mainly axial loads to which these structures may be subjected, originated from different sources, such as wind, water current, tide, etc., there may be cases when at least one of these lines may possibly face an abrupt, shock-like axial load of considerably larger magnitude. The goal of the present study is to evaluate the residual tensile strength of three different synthetic yarns (polyester, and two grades of high modulus polyethylene) after exposure to such axial impact loads. It was observed that, for the tested materials, polyester is the one with the largest impact resistance to the conditions evaluated herein, mainly because of its comparatively greater energy absorption properties.
Psychological, morphological and dietic aspects of violations of food behavior of young people
Authors: Filatova O. V. , Kutseva E. V. , Voronina I. Yu. 
Published: September 2022

Background: The article shows that the development of obesity and associated health disorders is directly related to the changes in eating behavior (EB) and the psychoemotional state. However, the considered studies were carried out in obese patients of medical institutions only. The research in young people focuses mainly on the sociological and psychological aspects of EB.Aim: To study the psychological characteristics, eating behavior features and their relationship with the indicators of actual nutrition and the body composition in young men.Materials and methods: A multicenter, cross-sectional sample survey of young men aged 17 to 21 was performed. A survey of violations of the EB was carried out, on the basis of which 5 groups of young men were formed. Group 1 (comparison) consisted of young men without violations of the EB. Group 2 consisted of young men with impaired emotiogenic EB. Group 3 consisted of boys with violations of the restrictive PP; group 4 — young men with impaired external EB; group 5 — young men with a combination of impairment of emotionogenic and restrictive EB. We used the Dutch DEBQ questionnaire to study the types of eating behavior. The current mental state of the testees was evaluated by a clinical and psychological test — Symptom Checklist-90-Revised (SCL-90-R). The body composition was assessed with the ABC-01 «Medass» bioimpedansometry device. The «Analysis of the human nutritional state” computer program was applied to estimate the actual nutrition by the frequency analysis method.Results: The study included 96 volunteers. Young men with impaired external EB feature an increase in the daily average energy consumption, which resulted in an increase in BFM%. In young people with eating disorders, an increase in scores on the «Somatization», «Obsession-compulsion», and «Anxiety» scales as compared to the reference valuesis testified. The depression level in young men correlated with the severity of emotiogenic eating behavior (r = 0.455, p <0.001).However, it is associated with the severity of external EB to a greater extent (r = 0.608, p <0.001). On the contrary, the anxiety level more strongly correlated with the severity of emotiogenic EB (r = 0.575, p <0.001) rather than of external EB type (r = 0.391, p <0.001).Conclusion: EB disorders in young men are associated with psychophysiological features, eating disorders accounting for the accumulation of adipose tissue in the body.
The first experience of using beta-hydroxybutyrate analysis of capillary blood in the diagnosis of non-diabetic hypoglycemia in adults
Authors: Yukina M. Yu. , Troshina E. A. , Nuralieva N. F. , Mokrysheva N. G. 
Published: September 2022

Background: The diagnostic threshold of β-hydroxybutyrate (BHB) at the moment of hypoglycemia in insulinoma was developed for venous blood many years ago, when there were no alternative ways to measure ketones. Number of works, mainly on patients with diabetes mellitus, found differences in the measurement of this indicator in venous and capillary blood, but the results were contradictory. Moreover, this study was not previously used in the diagnosis of non-diabetic hypoglycemia (NDH) in adults on the territory of the Russian Federation.Aim: To estimate the effectiveness of the method for determining BHB in capillary blood and its place in the diagnosis of NDH.Materials and methods: We conducted an experimental, cross-sectional, comparative study and included patients with suspected NDH who underwent a standard fast test. The BHB level in capillary blood was determined every 6 hours during the fast test and at its completion.Results: Based on the results of the fast test, the participants (n=154) were divided into groups: with hyperinsulinemic variant of NDH and IFRoma (n=98; group 1), with hypoinsulinemic variant of NDH /absence of NDH (n=56; group 2). When comparing the level of BHB at the moment of fasting completion, significant differences were obtained between groups 1 and 2 (p<0.001). According to the ROC analysis, the determination of BHB for differentiation the hyper- and hypoinsulinemic variants of hypoglycemia is characterized by excellent quality of model (AUC=99,1% [98,0%; 100,0%]). The BHB determination in capillary blood has the maximum diagnostic accuracy at a cut-off point of ≤ 1.4 mmol/L (Se 98.0%, Sp 96.4%, PPV 98.0%, NPV 96.4%, Ac 97.4%). Exceeding the diagnostic threshold of BHB was first recorded after 24h of fasting; at the same point, a significant difference was determined when comparing BHB indicators between two consecutive measurements (between 18h and 24h).Conclusion: The BHB determination in capillary blood is a highly sensitive and highly specific additional method for the differential diagnosis of NDH variants. The diagnostic threshold for BHB of capillary blood, which allows differentiating hyper- and hypoketonemic variants of NDH, is ≤1.4 mmol / L. It is advisable to initiate control of BHB in the blood no earlier than 18 hours after the start of the fast test.
Work Motivation and Self-Efficacy: Building Subjective Well-Being Teacher Raudhatul Athfal
Authors: Sri Lestari Sugeng , Muarifah Alif 
Published: September 2022

Purpose – Subjective well-being of a good teacher causes teachers to be more focused, productive, and confident that they can complete teaching tasks regardless of the difficulty. This study aims to determine the effect of self-efficacy and work motivation of teachers on sujective well-being.Design/methods/approach – This quantitative research was conducted by distributing questionnaires to 183 uncertified teachers. Obtained a sample of 118 teachers whose data were taken with area sampling. The measuring instrument used is the work motivation scale, self-efficacy scale, and subjective well-being scale. Research data is processed by multiple regression analysis with an assumption test.Findings – The results of the analysis test obtained R 0.644, 1 = 0.383 and 2 = 0.352 and a significance value of of 0.000 (ῥ < 0.001) providing an effective contribution of 41.85%. It shows that the hypothesis is accepted that there is a significant positive effect between the motivation and self-efficacy of teachers’ work on subjective well-being. The first minor hypothesis test has a partial coefficient value r of 0556 with a significance value of providing an effective contribution of 21.87%. There is a very significant positive influence between work motivation and subjective well-being. The results of the second minor hypothesis test have a partial coefficient value (r) of 0.571 with a significance value of 0.000 <0.01, giving an effective contribution of 19.57%. Some teachers did not have good subjective Well being in Raudhatul Athfal, Bantul Regency. There is a significant positive effect between teacher self-efficacy and subjective well-being. The higher the teacher’s self-efficacy, the greater the subjective Well being. The lower the self-efficacy, the lower the subjective well-being. Self-efficacy contributes 19.57%, and teacher work motivation contributes 21.87% to subjective well-being. Other factors influence the remaining 58.55%.Research implications/limitations – This study only explores internal factors and has not examined external factors that affect subjective well-being. This study’s limitations are that the three-dimensional items’ preparation does not suggest an unfavorable scale. Categorization of intrinsic motivation should be based on the type of teacher work motivation, not categorization based on high and low work motivation. Practical implications – Teachers can do their job well if they have high subjective well-being. It can be pursued by increasing work motivation and high self-efficacy both by the school and the teacher.Originality/value – This study is essential for teachers to have good work motivation and believe they can influence student learning outcomes, improving the teacher’s subjective well-being.
Paper type Research paper
KAJIAN JALUR PELABUHAN “MARINE SCIENCE TECHNO PARK UNDIP” TELUK AWUR JEPARA MENGGUNAKAN MULTIBEAM ECHOSOUNDER (MBES) DAN SISTEM INFORMASI GEOGRAFIS
Authors: Sasmito Bandi , Prasetyo Yudo , Sabri LM , Awaluddin Moehammad 
Published: September 2022

Universitas Diponegoro mempunyai Science and Technological Parks (STP) yang dibangun di Teluk Awur, Jepara yang diberi nama Marine Science Techno Park (MSTP). Dalam lingkungan MSTP terdapat fasilitas dermaga yang kini tidak dipergunakan dan terbengkalai. Penelitian ini bertujuan untuk mengaji jalur pelabuhan menuju dan keluar dermaga MSTP dengan data-data baru sehingga dermaga dapat dipergunakan. Metode yang digunakan adalah pengukuran kedalaman dengan peralatan Multibeam Echosounder (MBES). Sedangkan metode penentuan jalurnya menggunakan pemodelan dengan teknologi Sistem Informasi Geografis. Hasil pengolahan yang diharapkan adalah model dasar perairan MSTP dan analisis penentuan jalur pelabuhan keluar masuk dermaga yang disajikan secara spasial (Peta Tematik). Hasil diharapkan dapat digunakan sebagai bahan pertimbangan dalam perancangan dan perencanaan revitalisasi MSTP dalam jangka panjang.Kata kunci : Marine Science Techno Park, Multibeam Echosounder, Sistem Informasi Geografis
ANALISIS SEBARAN ALIRAN LAVA UNTUK PEMBUATAN PETA MITIGASI BENCANA GUNUNG SLAMET
Authors: Sudarsono Bambang , Yuwono Bambang Darmo 
Published: September 2022

Indonesia merupakan salah satu negara yang memiliki wilayah rawan bencana alam yang disebabkan oleh beberapa hal antara lain banjir, tanah longsor, tsunami, gempa bumi, dan erupsi gunung api. Diantara bencana alam yang terjadi sering membawa korban manusia antara lain adalah bencana alam karena erupsi gunung api. Erupsi gunung api yang terjadi dapat menghasilkan sejumlah bencana, seperti lava pijar, lahar, jatuhnya piroklastik dan awan panas. Apabila terjadi erupsi gunung api , maka akan menimbulkan bencana bagi warga masyarakat sekitarnya. Oleh karena itu diperlukan mitigasi bencana sebagai salah satu upaya untuk mengurangi dampak bencana erupsi gunung api. Berdasarkan uraian tersebut perlu dilakukan penelitian sebaran aliran lava untuk pembuatan peta mitigasi bencana berbasis penginderaan jauh dan Sistem Informasi Geografis (SIG). Pada penelitian ini akan dilakukan kajian terhadap prediksi sebaran aliran lava dan kajian pembuatan peta mitigasi aliran lava di wilayah Gunung Slamet. Analisis sebaran aliran lava dibuat dengan menggunakan data DEM TerraSAR dan citra satelit Sentinel 2-A yang akan digunakan untuk mengetahui klasifikasi tutupan lahan di lokasi penelitian. Selanjutnya data model permukaan digital dan data klasifikasi lahan diproses overlay untuk mendapatkan prediksi area lahan yang terkena dampat aliran lava. Dari analisis sebaran aliran lava dapat diketahui prediksi aliran lava dan dampak aliran lava di lokasi penelitian. Kemudian dapat ditentukan tingkat kerentanan dan luas area yang terdampak. Berdasarkan data dan analisis yang dilakukan, kemudian dapat dilakukan pembuatan peta mitigasi bencana aliran lava Gunung Slamet.