bluuebunny/crossref_metadata_2025_split huggingface dataset:
Musculocutaneous Latissimus Dorsi Phalloplasty
Authors: Bencic Marko , Stojanovic Borko , Bizic Marta , Djordjevic Miroslav L. 
Published: June 2022

AbstractThe treatment of gender dysphoria consists of psychiatric evaluation, initiation of hormonal therapy, and the final step in an individual's transition, performing gender-affirming surgery. Construction of the neophallus is one of the most demanding tasks in genital affirming surgery of transgender men. The main objectives of phalloplasty are to achieve a cosmetically acceptable and functional phallus, with a neourethra that allows voiding in standing position, sufficient length and strength for possible penetrative intercourse, preserved tactile and orgasmic sensation, and acceptable donor site morbidity. The musculocutaneous latissimus dorsi flap has reliable and suitable anatomy (good size, volume, and length of neurovascular pedicle) to meet the esthetic and functional requirements of neophallus reconstruction. Despite many advantages, the main disadvantage of this flap is the lack of sensitivity. Although the radial free forearm flap technique is the most commonly performed procedure, musculus latissimus dorsi flap is an acceptable choice in gender-affirming surgery.
The Value of Spiral Chest Computed Tomography Scan in the Diagnosis of Asymptomatic Coronavirus Carriers among Paranasal Sinus and Pharynx Surgery Candidates
Authors: Hasibi Mehrdad , Asadollahi-Amin Ali , Sharifian Hashem , Kazemi Mohammad Ali , Nazemi Pershang , Kouhi Ali , Iravani Babak Mohajer , SeyedAlinaghi SeyedAhmad 
Published: June 2022

Abstract
Introduction The nasopharynx and oropharynx are the main colonization sites of coronavirus. Therefore, patients with paranasal sinuses and pharyngeal problems (ear, nose, and throat [ENT] patients) predispose coronavirus infection.Ear, nose, and throat patients with concomitant asymptomatic coronavirus infection may develop severe pneumonia following surgical procedures. As a result, presurgical screening for coronavirus infection is a substantial concern.
Objective We evaluated the usefulness of a spiral chest computed tomography (CT) scan in the diagnosis of asymptomatic coronavirus infection in the presurgical assessment of ENT patients
Methods In this study, candidates of paranasal sinus or pharyngeal surgery were evaluated for coronavirus infection. Patients with neither history of coronavirus disease 2019 (COVID-19) nor compatible symptoms and signs were screened for asymptomatic coronavirus infection. These patients composed two groups: the first group underwent a reverse transcription polymerase chain reaction (RT-PCR) test of nasopharyngeal sample and spiral chest CT scan, but for the second one, only the latter was performed.
Results In the first group, which consisted of 106 patients, 11 (10.4%) cases had positive RT-PCR test results, and 17 (16%) patients showed positive findings in favor of coronavirus infection in the spiral chest CT scan. In the second group, which consisted of 173 patients, 34 (19.7%) cases had positive chest CT scan results.
Conclusion The chest CT scan has a valuable role in the early diagnosis of asymptomatic coronavirus carriers in patients highly predisposed to infection, especially in low resource areas, where the RT-PCR test is unavailable.
Adrenal Histoplasmosis: An Uncommon Cause of Adrenal Crisis in an Immunocompetent Man
Authors: Alnuaimi Mouza , Alblooshi Maitha , Alzaabi Amna , Elomami Abdulghani , Almazrouei Raya 
Published: June 2022

Abstract
Background Histoplasmosis is a rare cause of primary adrenal insufficiency. Adrenal involvement is commonly encountered with disseminated disease in immunocompromised individuals though some have been reported in immunocompetent patients. Primary adrenal histoplasmosis where adrenals are the only organs with demonstrable disease is uncommon.
Case Presentation A 33-year-old immunocompetent man presented with an adrenal crisis. Further evaluation of the underling etiology of primary adrenal insufficiency revealed bilateral adrenal enlargement that was confirmed to be histoplasmosis on adrenal biopsy.
Conclusion The case highlights the importance of considering histoplasmosis as an underlying cause of primary adrenal insufficiency in patients from high endemic areas.
Uso de cuestionarios reportados por pacientes en cirugía de pie y tobillo en Chile
Authors: Morales Sergio , Villa Andres , Palma Joaquin , Mery Pablo , Urrutia Tomas , Ledermann Gerardo , Vidal Catalina 
Published: June 2022

Resumen
Objetivo Describir el uso de los cuestionarios reportados por pacientes (patient-reported outcome measures, PROMs, en inglés) en cirugía de tobillo y pie en Chile.
Materiales y métodos Estudio descriptivo, transversal, en el que se diseñó y se aplicó una encuesta para conocer el uso de PROMs en Chile. Se invitó a participar a los traumatólogos cuya actividad principal fuese la cirugía de tobillo y pie.
Resultados En total, 73 de 110 traumatólogos contestaron la encuesta. El 75% de los encuestados ha utilizado PROMs al menos una vez, y el 50% los utiliza de manera regular. La finalidad con la que se utilizan es principalmente de investigación (83%), y su aplicación es realizada la mayoría de las veces por los médicos del equipo (94%). Se identificaron 15 cuestionarios distintos aplicados en nuestro medio, siendo los más utilizados la Escala Visual Análoga (EVA), la Escala de Tobillo y Retropié de la American Orthopaedic Foot and Ankle Society (AOFAS), el 36-item Short Form Health Survey (SF-36), y la Escala de Resultados de Tobillo y Pie (Ankle and Foot Outcome Score, FAOS, en inglés). Los encuestados que no han utilizado estos cuestionarios señalaron como principales limitantes la falta de información, de tiempo y de personal capacitado.
Conclusión El 75% de los traumatólogos dedicados a la cirugía de tobillo y pie encuestados ha utilizado PROMs en su práctica clínica. Existe una amplia variedad de cuestionarios aplicados, y el presente estudio constituye la primera aproximación de su aplicación en nuestro medio.
Nivel de evidencia: 4.
Atypical Posterior Reversible Encephalopathy Syndrome in Intraorbital Lymphoma after Tumor Biopsy: An Illustrative Case
Authors: Vongsfak Jirapong , Norasethada Thunya , Unsrisong Kittisak 
Published: June 2022

Abstract
Introduction A 63-year-old male presented with visual loss and left eye proptosis. Magnetic resonance imaging revealed a left orbital tumor, measuring 1.4 cm × 0.9 cm. The patient underwent left frontotemporal craniotomy to perform a biopsy of the tumor. During the postoperative period, the patient developed the first episode of a generalized tonic–clonic seizure.
Case Summary Computed tomography of the brain showed hypodensity of the bilateral basal ganglia and thalami with associated edematous white matter hypodensity of bilateral temporo-occipital lobes compatible with atypical posterior reversible encephalopathy syndrome (PRES). The patient received antiepileptic medication and was observed for clinical seizure. One week later, computed tomography of the brain showed the reversible process of PRES. The pathology report revealed diffuse large B cell lymphoma. Following pathological diagnosis, the patient received treatment with whole-brain radiotherapy.
Conclusion This is the first reported case of atypical PRES associated with orbital lymphoma following craniotomy for the purpose of tumor biopsy. Early detection as well as seizure and blood pressure control, is essential for the proper treatment of PRES.
Visible light modulator by sputter-deposited lithium niobate
Authors: Fukuzawa Hideaki , Yoshinari Jiro , Hara Hiroki , Sasaki Kenji , Take Hiroshi , Yoshida Makoto , Shimura Atsuhi , Kikukawa Takashi 
Published: June 2022

Thin-film lithium niobate (LN) modulators have significant potential for ultra-high-speed optical communications. Although a significant cost reduction of the modulator is needed to satisfy the growing demands of huge data communications, all the existing studies of thin-film LN modulators were fabricated using the adhesion process of bulk LN to a substrate, and it severely constrains the use case of LN modulators. In order to overcome this critical issue, we have deposited thin-film LN (006) directly on a Al2O3 sapphire (001) substrate and fabricated LN modulators by using the wafer process. Furthermore, previous studies have been largely limited to the use of infrared light (typical wavelengths λ = 1550 nm), which also constrains half-wave voltage and interaction electrode length (Vπ · L) required for modulation. Small Vπ · L is essentially important not only for small die size with lower cost but also for small voltage operation by using a complementary metal oxide semiconductor. Here, we demonstrate the modulation of red (λ = 637 nm), green (λ = 520 nm), and blue (λ = 473 nm) visible light using sputter-deposited thin-film LN; the product of the half-wave voltage and interaction electrode length (Vπ · L) was 1.9, 1.4, and 1.2 V cm, respectively: it decreased with the decreasing wavelength. Thus, LN modulators can be adopted for emerging applications of visible light communications, and wafer-level fabrication using sputter-deposited thin-film LN provides opportunities for future mass production with a much lower fabrication cost.
Implementation of rapid microwave sintering using a 24 GHz gyrotron system
Authors: Egorov S. V. , Eremeev A. G. , Kholoptsev V. V. , Plotnikov I. V. , Rybakov K. I. , Sorokin A. A. 
Published: June 2022

Rapid microwave sintering of different oxide ceramics with heating rates up to 300 °C/min and zero hold time has been implemented using a 24 GHz gyrotron-based system for high-temperature processing of materials. The design of the system, principle of operation, and process control are described. Particular attention is given to the design of thermal insulation assemblies and the implementation of temperature measurement in an environment with intense electromagnetic fields. A description of an optical system for dilatometry and temperature measurement is presented. The interrelation between the automatically regulated output power of the gyrotron and the microwave power absorbed volumetrically in the sample is analyzed on the basis of energy balance considerations. The analysis is illustrated by considering examples of rapid sintering processes with ZnO-based and BaTiO3 ceramic samples making use of direct and susceptor-assisted microwave heating. It is demonstrated that an increase in the volumetrically absorbed power leads to the development of a controlled thermal instability, which results in a lower temperature of the densification onset.
CLIL in the 21st Century
Authors: Dalton-Puffer Christiane , Hüttner Julia , Llinares Ana 
Published: June 2022

Abstract
This article traces the historical phases in the conceptualisation of and research on
Content-and-language-Integrated Learning in Europe since the 1990s. Following upon early programmatic statements, the first wave
of CLIL research concentrated on language learning outcomes. In a second wave, the focus was on descriptions of practice and
studies of participant perspectives. More recently, studies have focused on the unique character of CLIL as an educational
approach in its own right, not simply as a context of foreign language teaching. The crucial content-language interface is being
addressed in research focusing on language and literacy in content curricula and classroom practices. A new CLIL research focus is
the development of pedagogical practice through theory-based interventions. In line with the UN sustainable development goal of
Quality Education, we identify equity and team work as future challenges and argue that CLIL could be a catalyst for a more
collaborative and multidisciplinary approach in education.
Turbulence, Atmosphere and Climate Dynamics
Authors: Mokhov I I , Chkhetiani O G , Repina I A 
Published: June 2022

Abstract
The conference "Turbulence, Atmosphere and Climate Dynamics" dedicated to the memory of the Alexander M. Obukhov was held in Moscow from November 10 to 12, 2020. The topics of the conference covered the following scientific areas: turbulence; geophysical hydrodynamics; atmospheric and climate system dynamics; physics and composition of the atmosphere; air-sea interaction; wave propagation. The conference showed a high scientific level of almost all the presentations. Studies of turbulent, climatic and atmospheric processes are traditionally conducted in our country at the highest level, as evidenced by the publication in high-ranking scientific journals and the active participation of Russian scientists in international programs.
List of Program committee, Organizing committee are avilable in this pdf.
Estimating the parameters of wind turbulence from spectra of radial velocity measured by a pulsed Doppler lidar
Authors: Banakh V A , Smalikho I N 
Published: June 2022

Abstract
The paper proposes the method for estimating the turbulence energy dissipation rate and the variance of the vertical component of the wind velocity vector from the spectral density of radial velocity measured by a pulsed coherent Doppler lidar. The method takes into account the averaging of the radial velocity over the probing volume. It is shown that neglecting the spatial averaging leads to the understating the dissipation rate.
Influence of aerosols on the meteorological regime of Northern Eurasia according to COSMO-Ru Model
Authors: Poliukhov A A , Blinov D V 
Published: June 2022

Abstract
We provided the estimation of the aerosols effect at the surface and at the top of the atmosphere, as well as on the sensible and latent heat flux for the Northern Eurasia using the MACv2 aerosol climatology. The numerical experiments were performed with the COSMO-Ru model for the January and July in 2017. It is found that the aerosol radiation effect on the surface can reach -50 W/m2. At the same time, it is shown that the net shortwave radiation increase does not unequivocally leads to the air temperature at two meters increase. We revealed that the temperature at 2 meters decreases on -0.5±0.1 degrees per 100 W/m2 in the clear sky condition for Mediterranean, Red, Black and Caspian seas areas. The temperature sensitivity is positive and equals 0.9±0.3 degrees per 100 W/m2 for Middle East and southern Europe and 1.7±0.7 degrees per 100 W/m2 for northern Africa.
Three decades of remote sensing of NO2 vertical distribution and column content at the A. M. Obukhov Institute of Atmospheric Physics
Authors: Gruzdev A N , Elokhov A S 
Published: June 2022

Abstract
The paper reviews the results of 30-year spectrometric measurements of vertical distribution and column content of NO2 at the Zvenigorod Scientific Station (ZSS) of the A. M. Obukhov Institute of Atmospheric Physics and presents analysis of NO2 long-term trends and interannual variations. The station is located in the western Moscow region. It is part of the Network for the Detection of Atmospheric Composition Change (NDACC). Measurements are done in the morning and evening twilight by zenith-scattered visible solar radiation. Vertical NO2 profiles are retrieved and column NO2 contents are calculated by profile integration. Long term trends and inter-annual variations of NO2 are analysed by multivariate regression method taking into account autocorrelation of data in a wide range of time scales. Seasonally dependent estimates of NO2 trends and interannual variations due to the quasi-biennial oscillation, El Nino–Southern oscillation, North Atlantic Oscillation, and the 11-year solar cycle are obtained. Most pronounced (in per cent units) trends and circulation and solar cycle effects are peculiar to the winter–spring period of the year. Mutual influence is assessed between the estimates of the trend and the solar cycle effect in stratospheric NO2.
Temporal variations of downward solar radiation, aerosol optical thickness and cloudiness over North of the European part of Russia based on surface data records (during 40 years)
Authors: Plakhina I N , Repina I A , Makhotkina E L 
Published: June 2022

Abstract
The results of the analysis of temporal changes in the aerosol optical thickness of the atmosphere, the factor of turbidity, cloudiness and incoming solar radiation near the Earth's surface in the north of the European Territory of Russia (ETR) based on observations of the Roshydromet actinometric network for 1976—2014 are presented. Trends of synchronous changes in the above parameters have been revealed, both for the entire observation period and in the post-volcanic period (1995—2014). Under conditions of the aerosol optical thickness (AOT) decreasing (an increasing of the transparency of the atmosphere) for average cloudiness, a neutral time dependence of the incoming radiation is observed. Comparison with the results at actinometric stations in the south of ETR was carried out.
Study of biogas utilization as waste-to-energy plant and transport modelling of iron (Fe), lead (Pb) and copper (CU) in leachate at Muara Fajar landfill Pekanbaru
Authors: Yuvendius H , Zondra E , Zainuri  , Sari V I 
Published: June 2022

Abstract
Daily activities such as household, restaurants, markets and others especially in Pekanbaru city will produce waste. Waste produced is both organic and inorganic. A biogas utilization study has been conducted at the Muara Fajar landfill and 888.6 kW potential electricity has been obtained. Each landfill will produce leachate containing metals such as iron (Fe), lead (Pb), copper (Cu) and others. The level of metal toxicity will increasingly pollute the environment. Using the PHREEQC Interactive version 3.0.6.7757 modeling of these contaminants, it can be predicted the transport of the elements and at the same time reduce the risk of soil and water pollution. Modeling with parameter condition of the presence of dolomite show that concentration of Ca, Mg and Na metal decreased, while Cu metal showed a significant increase in the 10th to 50th years and stable at Cu concentration 1.4 mg/L. Lead (Pb) also increased from the 20th to 60th year and stable at Pb concentration 0.25 mg/L. In conditions without dolomite, concentration of iron (Fe) increase in the 15th year namely 0.175 mg/L and constant for the following year while Ca, Na and K have decreased to reach zero concentration.
The Utilization of Three-Dimensional Printing in Creating a Surgical Instrument: An Areola Cookie Cutter
Authors: Burhamah Waleed , Alshawaf Solaiman M , Alwazzan Sabika , AlYouha Sarah , Al-Sabah Salman 
Published: June 2022

Abstract
Three-dimensional (3D) printing is a rapidly evolving technology with many applications in the medical field. It involves printing solid objects from a digital file. In this paper, we describe our experience with the use of 3D printing in creating an areola cookie cutter that is compatible with sterilization. The objective of this study is to explore accurate and cost-effective methods of producing patient-specific areola cookie cutters. Auto computer-aided design (CAD) 3D software was used to design a digital model that was subsequently converted to a standard tessellation language (STL) file. The models were printed with the Formlabs Form 3+ SLA printer (Somerville, MA) using a resin material. Washing and curing were then performed followed by autoclave sterilization of the models. A total of 3 areola cookie cutters were created, each with different sizes (33, 38, and 42 mm) using resin material (Formlabs BioMed Clear Resin; Somerville, MA). All 3 models were able to withstand autoclave sterilization. The use of 3D printing has proven to be a valuable tool in Plastic surgery. We describe our experience of designing and producing an areola cookie cutter using a 3D printer; our model is compatible with the process of sterilization. We emphasize the advantages of a quick production time and accuracy in design.
The Cdc25/Ras/cAMP-dependent protein kinase A signaling pathway regulates proline utilization in wine yeast Saccharomyces cerevisiae under a wine fermentation model
Authors: Nishimura Akira , Ichikawa Kazuki , Nakazawa Hayate , Tanahashi Ryoya , Morita Fumika , Sitepu Irnayuli , Boundy-Mills Kyria , Fox Glen , Takagi Hiroshi 
Published: June 2022

ABSTRACT
Proline is a predominant amino acid in grape must, but it is poorly utilized by the yeast Saccharomyces cerevisiae in wine-making processes. This sometimes leads to a nitrogen deficiency during fermentation and proline accumulation in wine. In this study, we clarified that a glucose response is involved in an inhibitory mechanism of proline utilization in yeast. Our genetic screen showed that strains with a loss-of-function mutation on the CDC25 gene can utilize proline even under fermentation conditions. Cdc25 is a regulator of the glucose response consisting of the Ras/cAMP-dependent protein kinase A (PKA) pathway. Moreover, we found that activation of the Ras/PKA pathway is necessary for the inhibitory mechanism of proline utilization. The present data revealed that crosstalk exists between the carbon and proline metabolisms. Our study could hold promise for the development of wine yeast strains that can efficiently assimilate proline during the fermentation processes.
Batch alignment via retention orders for preprocessing large-scale multi-batch LC-MS experiments
Authors: Malinka František , Zareie Ashkan , Prochazka Jan , Sedlacek Radislav , Novosadova Vendula 
Published: June 2022

AbstractMotivationMeticulous selection of chromatographic peak detection parameters and algorithms is a crucial step in preprocessing liquid chromatography–mass spectrometry (LC-MS) data. However, as mass-to-charge ratio and retention time shifts are larger between batches than within batches, finding apt parameters for all samples of a large-scale multi-batch experiment with the aim of minimizing information loss becomes a challenging task. Preprocessing independent batches individually can curtail said problems but requires a method for aligning and combining them for further downstream analysis.ResultsWe present two methods for aligning and combining individually preprocessed batches in multi-batch LC-MS experiments. Our developed methods were tested on six sets of simulated and six sets of real datasets. Furthermore, by estimating the probabilities of peak insertion, deletion and swap between batches in authentic datasets, we demonstrate that retention order swaps are not rare in untargeted LC-MS data.Availability and implementationkmersAlignment and rtcorrectedAlignment algorithms are made available as an R package with raw data at https://metabocombiner.img.cas.czSupplementary informationSupplementary data are available at Bioinformatics online.