bluuebunny/crossref_metadata_2025_split huggingface dataset:
Simultaneous malignant hyperthermia reactions in two siblings during living donor liver transplantation
Authors: Majeed A. , Chaiah Y. , Latif N. , Tahir A. , Mahmood A. 
Published: February 2022

SummaryWe report a case of simultaneous malignant hyperthermia reactions occurring in two siblings during living donor liver transplantation. This report highlights the conflicting goals in the clinical management of liver transplantation and malignant hyperthermia, including the use of total intravenous anaesthesia and dantrolene in the face of the potential for drug‐induced hepatotoxicity in the remnant liver or transplanted liver graft, as well as cautious fluid management needed for liver transplantation balanced against the liberal fluid therapy required to prevent acute kidney injury associated with malignant hyperthermia. The logistical challenges of managing this emergency in two closely related patients are discussed, including rapid preparation of two vapour‐free anaesthesia machines, the need for availability of additional dantrolene and the requirement for additional personnel. Prompt recognition, immediate removal of the triggering agents and conversion to total intravenous anaesthesia helped to curtail the malignant hyperthermic reactions in our patients, both of whom made a full recovery.
Characterization of column flow regimes on horizontal tubes for falling‐film systems: An experimental approach
Authors: Kandukuri Prudviraj , Deshmukh Sandip , Katiresan Supradeepan 
Published: February 2022

AbstractThe intertube flow regimes and hydrodynamic behavior of the liquid profile have a significant impact on the functioning of falling‐film evaporators. Column flow is one of the fundamental flow modes, which is actively observed in many industrial evaporators. A high‐speed digital photographic device is utilized to visualize the complete progression of column flow phases for intertube distances of 10/20/30/40 mm and Reynolds number (Re) values ranging from 41 to 583. The Sobel edge detection algorithm is implemented to quantify the flow parameters for each frame of a sequence. The research results indicated that the column flow regime between the inline horizontal tubes can be broadly classified into the following phases: columnar droplet flow, periodic column flow, satellite drops column flow, drift column flow, and mixing liquid film column flow. The findings show that the liquid jet diameters between the tubes range from 1.6 to 8.46 mm, an increase in the liquid jet diameter with Re and a decrease with tube‐to‐tube distance. The axial coverage of the liquid film profile beneath the tube differed from 2.07 to 3.99 mm and over the tube surface ranged from 1.14 to 2.68 mm. The formation of dry spots and flooding is a major problem in the operation of falling‐film heat exchangers. The shape and size of the liquid jet have a direct impact on the interfacial area; understanding the entire progression of column flow regimes, as well as their characteristics, can help designers avoid the aforementioned problem.
More utilitarian judgment in Internet addiction? An exploration using process dissociation and the CNI model
Authors: Lu Jianxia , Xie Junjie , Chen Jin , Zeng Yan , Jiang Zhongli , Wang Yunqiang , Zheng Hui 
Published: February 2022

AbstractBackgroundInternet addiction (IA), which is disadvantageous for decision making, such as moral judgment, is a pernicious threat to contemporary societies. However, few studies consider social cognition abilities as an important variable in IA.ObjectivesThis study explores the psychological mechanism of IA facing the moral dilemma.MethodsForty participants with IA and 89 healthy participants were recruited. They finished the Internet Addiction Test and completed the moral judgment task. The process dissociation (PD) method and the consequences, norms, and generalized inaction (CNI) model were used to analyze moral judgment data.ResultsCompared with the healthy control (HC) group, the traditional analysis showed that the IA group made more utilitarian judgment regarding moral dilemmas. PD analysis showed that the IA group had decreased deontological inclination, without utilitarian inclination. The CNI model further showed that the sensitivity of the IA group to moral rules was significantly lower than that of the HC group, while there was no significant difference between groups in the sensitivity to the consequences and the general preference for action.ConclusionsIndividuals with IA make more utilitarian judgment when faced with a moral dilemma, which is related to their weak sensitivity to moral norms.
Heavy head lice infestation in an adolescent girl following benzodiazepine poisoning
Authors: Moghimi Minoo , Nekoukar Zahra , Sharifpour Ali , Zakariaei Zakaria , Fakhar Mahdi , Soleymani Mostafa 
Published: February 2022

AbstractLoss of consciousness (LOC) is one of the most common causes of emergency department (ED) visits. It may be due to intoxication or hypoglycemia. We present a 15‐year‐old girl who was referred with heavy head lice and LOC to the ED in the north of Iran.
Mature cystic teratoma of the temporal lobe: A rare tumor with an unusual location
Authors: Rijal Yasoda , Shah Om Bikram , Shrestha Suraj , Shrestha Bibek Man , Bhattarai Shiva Lal , Bishowkarma Sabita , Sedhai Gopal 
Published: February 2022

AbstractIntracranial mature cystic teratoma is rare. The temporal lobe is a very unusual location and can pose a considerable diagnostic challenge. Proper histological diagnosis and long‐term follow‐up are imperative.
An Innovative Sensor Based on Chitosan and Graphene Oxide for Selective and Highly‐Sensitive Detection of Serotonin
Authors: Tertis Mihaela , Sîrbu Petra‐Lia , Suciu Maria , Bogdan Diana , Pana Ovidiu , Cristea Cecilia , Simon Ioan 
Published: February 2022

AbstractA biomimetic electrochemical sensor based on molecularly imprinted polymer (MIP) containing chitosan and graphene oxide was designed for direct highly sensitive and selective detection of serotonin, an important neurotransmitter, with a significant role in various body functions, in real samples such as serum, tears and saliva. The composite MIP film was immobilized in a reproducible manner onto the glassy carbon electrode (GCE) via amperometry while the optimization and complete characterization of the sensor was performed with cyclic voltammetry, electrochemical impedance spectroscopy, scanning electron microscopy (SEM), atomic force microscopy (AFM) and X‐Ray Photoelectron Spectroscopy (XPS). The direct electrochemical detection based on the oxidation signal of the target analyte was performed by differential pulse voltammetry, the biomimetic sensor exhibiting a wide dynamic range (5 nm–10 μm), with an estimated limit of detection of 1.6 nm. The sensor demonstrated reproducibility, stability in time and reusability, excellent selectivity over other possible interferents and good recoveries in real samples, being promising for biomedical applications.
Batteriechemie im Aufwind
Authors: Gandert Etwina , Reubold Michael 
Published: February 2022

AbstractDie Lanxess‐Tochter Saltigo ist in die Herstellung von Batteriechemikalien eingestiegen. Kathodenmaterialien und Elektrolytkomponenten wie das Leitsalz Lithiumhexafluorophosphat gehören zu Produkten. Der Markt für Elektromobilität und Energiespeicher bietet eine Reihe von Chancen für den Konzern.
Drehmoment‐kontrolle verhindert‐ Auslaufen beim ‐Verschließen
Authors: Musat Michael 
Published: February 2022

AbstractGesichtsmasken mit Pressverschluss, Nagellackentferner in Schraubflaschen oder Sonnensprays mit Sprühpumpe und überkappe: Beim Kosmetikhersteller Mann & Schröder Cosmetics werden Pflegeprodukte mit teils stark variierender Konsistenz in entsprechende Behältnisse gefüllt und verschlossen. Die dabei eingesetzten Anlagen müssen trotz kurzfristiger Medienwechsel sowie variierender Füllvolumina präzise dosieren. Zudem dürfen die Verschlusskappen nicht zu stark oder zu lose aufgesetzt werden, um das Auslaufen oder eine Beschädigung des Behältnisses zu verhindern. Daher setzt das Kosmetikunternehmen seit Jahren auf die Abfüll‐ und Verschließsysteme der RATIONATOR Maschinenbau GmbH. Bei der neuesten Abfüllanlage handelt es sich um eine Serienmaschine mit angepassten Ausstattungsmerkmalen.
Psychological needs and support among patients and families undergoing food oral immunotherapy
Authors: Polloni Laura , Muraro Antonella , Bonaguro Roberta , Toniolo Alice , Ballin Anna , Guarnaccia Alberto , Lazzarotto Francesca 
Published: February 2022

AbstractBackgroundOral immunotherapy (OIT) is a promising treatment for food allergy (FA) however it is a challenging process for patients and parents. Induction can generate stress and anxiety. This may in turn affect their motivation and ability to cope with OIT challenges.ObjectiveThis study aimed to investigate psychological needs and support to patients/parents undergoing food OIT assessing participants' main characteristics, reasons for seeking psychological support, OIT phase and related psychological difficulties, type and timing of treatments and patients' perception of the effectiveness of the intervention.MethodsThis is an observational, retrospective study. 50 psychological interventions required for OIT related problems were selected consecutively in a Referral Centre in North‐Eastern Italy. All patients had a medical diagnosis of FA and were undergoing OIT or had just discontinued it. Data were collected from hospital records. A descriptive statistical analysis was performed.Results66% of patients asked for psychological support for the initial phase (e.g., oral food challenge, first maintenance doses), 20% during the up‐dosing phase, 8% during maintenance and 6% after discontinuation. 70% of treatments were required mainly because of emotional problems including dysfunctional anxiety and mood disorders, increased distress and excessive worry and/or fear related to OIT; 20% because of difficulties in managing OIT; 10% because of eating difficulties; 50% of patients reported recent anaphylaxis. All patients reported improvement and felt the psychological intervention was helpful.ConclusionIt is recommended to evaluate the psychological needs in profiling patients and families suitable to OIT and offer specific psychological support when needed.
Synthesis of Dihydrobenzofuro[3,2‐b]chromenes as Potential 3CLpro Inhibitors of SARS‐CoV‐2: A Molecular Docking and Molecular Dynamics Study
Authors: Gorai Sudip , Junghare Vivek , Kundu Kshama , Gharui Sowmomita , Kumar Mukesh , Patro Birija Sankar , Nayak Sandip K. , Hazra Saugata , Mula Soumyaditya 
Published: February 2022

AbstractThe recent emergence of pandemic of coronavirus (COVID‐19) caused by SARS‐CoV‐2 has raised significant global health concerns. More importantly, there is no specific therapeutics currently available to combat against this deadly infection. The enzyme 3‐chymotrypsin‐like cysteine protease (3CLpro) is known to be essential for viral life cycle as it controls the coronavirus replication. 3CLpro could be a potential drug target as established before in the case of severe acute respiratory syndrome coronavirus (SARS‐CoV) and Middle East respiratory syndrome coronavirus (MERS‐CoV). In the current study, we wanted to explore the potential of fused flavonoids as 3CLpro inhibitors. Fused flavonoids (5a,10a‐dihydro‐11H‐benzofuro[3,2‐b]chromene) are unexplored for their potential bioactivities due to their low natural occurrences. Their synthetic congeners are also rare due to unavailability of general synthetic methodology. Here we designed a simple strategy to synthesize 5a,10a‐dihydro‐11H‐benzofuro[3,2‐b]chromene skeleton and it's four novel derivatives. Our structural bioinformatics study clearly shows excellent potential of the synthesized compounds in comparison to experimentally validated inhibitor N3. Moreover, in‐silico ADMET study displays excellent druggability and extremely low level of toxicity of the synthesized molecules. Further, for better understanding, the molecular dynamic approach was implemented to study the change in dynamicity after the compounds bind to the protein. A detailed investigation through clustering analysis and distance calculation gave us sound comprehensive data about their molecular interaction. In summary, we anticipate that the currently synthesized molecules could not only be a potential set of inhibitors against 3CLpro but also the insights acquired from the current study would be instrumental in further developing novel natural flavonoid based anti‐COVID therapeutic spectrums.
An efficient data science technique for IoT assisted healthcare monitoring system using cloud computing
Authors: Lakshmanan Karthikeyan , Arumugam Samydurai 
Published: February 2022

AbstractIn this era of smart healthcare system, patient expects better healthcare support with low cost which satisfy through the innovative process such as Internet of Things (IoT), cloud computing and data science techniques. Meantime, the healthcare industry faces many problems including the data collection and storage for further progress. For healthcare monitoring system, the data collection and data analytics plays important role to screening the patient health. Therefore, data science techniques and cloud computing are heart for the healthcare system to resists several problems in terms of technical aspects. For further enhancement, efficient data science technique is proposed for IoT assisted healthcare monitoring (DST‐HM) system using cloud computing, which improves the data processing efficiency, data accessibility in cloud. The several IoT sensors are used in a person corpse to collect the real clinical data. The composed data are then maintained in cloud for added data science processing. In DST‐HM system, we first introduce a modified data science technique that is, improved pigeon optimization (IPO) algorithm for grouping the cloud stored data which enhances the prediction rate. Second, we illustrate the optimal feature selection technique for feature extraction and selection.
Multi‐scale point cloud registration based on topological structure
Authors: Dong Tianzhen , Zhao Yuepeng , Zhang Qing , Xue Bin , Li Jinghua , Li Wenju 
Published: February 2022

AbstractThe establishment of point‐to‐point correspondence between point clouds is called three‐dimensional point matching, which is widely used in computer vision, computer graphics, robotics and other fields. When the scale of source point cloud and target point cloud are different, it brings great difficulties to obtain the satisfactory matching result. Therefore, the article proposes a registration algorithm to solve this problem effectively. First, we construct a multi‐scale space related to Gaussian standard deviation. Second, we use a topological similarity of two directed trees constructed by feature points coming from two point clouds for fuzzy matching. Finally, we use local matching and global matching methods to find the corresponding relationship between patches in multi‐scale space. We find the feature correspondence of different scales in multi‐scale space and get the scale factor. Our method improves the accuracy of matching by eliminating mismatch caused by descriptor matching and local geometry matching. We show great performance of our approach by conducting extensive experiments, which outperforms other state‐of‐the‐art methods, in particular, it provides a valuable tool for point cloud registration.
On‐line Electrode Dissolution Monitoring during Organic Electrosynthesis: Direct Evidence of Electrode Dissolution during Kolbe Electrolysis
Authors: Ranninger Johanna , Nikolaienko Pavlo , Mayrhofer Karl J. J. , Berkes Balázs B. 
Published: February 2022

AbstractElectrode dissolution was monitored in real‐time during Kolbe electrolysis along with the characteristic products. The fast determination of appropriate reaction conditions in electro‐organic chemistry enables the minimization of electrode degradation while keeping an eye on the optimal formation rate and distribution of products. Herein, essential parameters influencing the dissolution of the electrode material platinum in a Kolbe electrolysis were pinpointed. The formation of reaction products and soluble platinum species were monitored during potentiodynamic and potentiostatic experiments using an electroanalytical flow cell coupled to two different mass spectrometers. The approach opens new vistas in the field of electro‐organic chemistry because it enables precise and quick quantification of dissolved metals during electrosynthesis, also involving electrode materials other than platinum. Furthermore, it draws attention to the vital topic of electrode stability in electro‐organic synthesis, which becomes increasingly important for the implementation of green chemical processes utilizing renewable energy.
The role of perceived workplace safety practices and mindfulness in maintaining calm in employees during times of crisis
Authors: Vu Thinh‐Van , Vo‐Thanh Tan , Chi Hsinkuang , Nguyen Nguyen Phong , Nguyen Duy Van , Zaman Mustafeed 
Published: February 2022

AbstractWhile prior studies in human resource management have investigated how employee outcomes have been affected in high‐risk workplaces, this study stands out by examining this issue through the role played by COVID‐19 as a specific stressor. We explained how employees' perceived health risks due to COVID‐19 (CV19PHR) and perceived workplace safety practices (PWSPs) affected job performance via burnout and how PWSPs moderated the CV19PHR–burnout and CV19PHR–JP relationships. We also examined how mindfulness moderated the direct effects of CV19PHR and PWSPs on burnout and JP and the indirect effects of CV19PHR and PWSPs on JP via burnout. We performed three studies using an explanatory sequential mixed‐method design. In study 1, a three‐phase survey with 987 respondents was conducted to test the hypotheses. In study 2, by analyzing verbatim from 22 informants, the findings of study 1 and some main points concerning mindfulness and PWSPs were explained. In study 3, using data from 12 informants, we investigated how COVID‐19 affected individuals differently compared with other high‐risk workplaces and whether the impact of COVID‐19 on individuals was curvilinear. We demonstrated that employees' CV19PHR was positively correlated with burnout, negatively influencing JP. Moreover, PWSPs reduced burnout, which adversely affected JP. Interestingly, PWSPs positively moderated the CV19PHR–burnout relationship but not the CV19PHR–JP relationship. We also found that mindfulness moderated the CV19PHR–burnout and PWSPs–burnout relationships. Furthermore, mindfulness significantly moderated the mediating effects of burnout on the CV19PHR–JP and PWSPs–JP relationships.
Bio‐Cyber‐Physical Systems: from concepts to human‐systems integration engineering
Authors: Gechter Franck , Fass Didier 
Published: February 2022

AbstractEngineering a technical system that must be coupled to humans is generally a tough task. One of the main reasons is that two systems, different by nature, must be coupled. Even if, there has been a strong effort to include Human factors in engineering processes, there is still a lot of issues to tackle with. Indeed, the adaptation of technical centered engineering processes to human concerns is not necessary the best solution. The Human‐machine design process requires then to consider the system as a whole and not as a composition of heterogenous elements. This is the key towards efficient and adaptative systems. The goal of the paper is both a conceptual and theoretical effort to ground Human‐Systems Integration as a discipline_and to propose a framework aimed at helping the engineering of Bio‐Cyber‐Physical Systems (Bio‐CPS).
Influence of Estimated Mission Data on Air Mission Commander Situation Awareness During Datalink Loss
Authors: Meyer Carsten , Kreutz Tobias , Schulte Axel 
Published: February 2022

AbstractThis article presents the impact of displaying accurate or inaccurate position estimates on air mission commanders’ (AMC) situation awareness (SA) during datalink interruptions between AMC and unmanned aerial vehicles (UAVs). The lack of current information about UAV state and position during datalink interruptions is suspected to negatively influence the controlling AMC's SA. We assume that the AMC's SA can be supported by displaying a state estimate, based on last transmitted data, instead of displaying last known position. An experimental evaluation in a full‐mission research cockpit simulator showed improvements in subjective SA with estimate shown. Objective SA only improved, if the estimate was accurate. Although we expected a negative impact of inaccurate estimates on objective SA (since the user might falsely trust it), none could be observed. Improvements in SA with accurate estimates, but no observable degradations with inaccurate estimates suggest benefits of showing an estimate in any case.
Model Based HSI & Operational Process Simulation
Authors: Peleg Eran , Gavish Nirit , Zonnenshain Avigdor 
Published: February 2022

AbstractHuman‐Systems Integration (HSI) activities are focused on the human engineering aspects of the systems designing, manufacturing, operation, and maintenance. It is part of the system engineering process. Model‐Based Systems Engineering (MBSE) is a concept, which is implemented by languages and software tools, for supporting all activities of development, operation, and system retirement, using a set of coherent models. This paper proposed how MBSE usage can be used to support the holistic HSI, from requirements and operational analysis, through retirement. The suggested methodology, which includes the use of Operational Process (OP) diagrams and model‐based 3D (three dimensional) simulation, can be applied to introduce further discipline and rigor to address complex HSI, marking an improvement over current document‐based practice.
Development of a digital twin for collaborative decision‐making, based on a multi‐agent system: application to prescriptive maintenance
Authors: Lorente Quentin , Villeneuve Eric , Merlo Christophe , Boy Guy André , Thermy François 
Published: February 2022

AbstractThe fourth industrial revolution involves more complexity. This research effort focuses on decision‐making in helicopter engine maintenance activities. Such a decision‐making task is difficult and relies on a variety of experts who only have partial knowledge and incomplete situation awareness, due to the great diversity of everyday operational practices. In this paper, we propose a digital twin multi‐agent approach to collaborative decision‐making in prescriptive maintenance.
Implementing HSI Research in COTS Tools
Authors: Dam Steven H. 
Published: February 2022

AbstractIn this paper, we describe the process for taking Human Systems Integration (HSI) research developed by George Mason University for creating high quality standard operating procedures (SOPs) and using that information to modify a commercial off‐the‐shelf tool, Innoslate®, to create a new tool, Sopatra®, that aids SOP developers in creating and verifying that the procedures work within the Allowable Operational Time Window (AOTW). The tool compares the AOTW with the Time on Procedure (ToP) to create new metrics: Procedure Buffer Time (PBT) and Probability of Failure to Complete (PFtC). A new Natural Language Processing (NLP) technique was developed as well.