bluuebunny/crossref_metadata_2025_split huggingface dataset:
Präventionsdilemma auf kommunaler Ebene?
Authors: Herbert-Maul Annika , Abu-Omar Karim , Till Maike , Fleuren Tobias , Wolff Andrea R. , Reimers Anne K. 
Published: July 2022

Zusammenfassung
Hintergrund
Von Gesundheitsförderung profitieren häufig vorwiegend sozial privilegierte Personen während sozial Benachteiligte seltener erreicht werden. Ob dieses Präventionsdilemma auch auf kommunaler Ebene besteht, wurde bislang kaum erforscht.

Ziel der Arbeit
Die Studie untersucht anhand von zwei bayernweiten Projektausschreibungen zur kommunalen Bewegungsförderung, ob sozioökonomisch deprivierte Kommunen, die geringe Angebotsstrukturen der Gesundheitsförderung aufweisen, durch solche Ausschreibungen erreicht werden und welche Faktoren die Bereitschaft zur Beteiligung beeinflussen.

Methoden
Es werden Bevölkerungsdaten und sozioökonomische Deprivationsdaten von (n = 171) Kommunen aus drei Gruppen (teilnehmende/interessierte Kommunen und deprivierte Vergleichskommunen) verglichen. Durch eine systematische Internetrecherche werden die Gesundheitsförderungsaktivitäten ausgewählter Kommunen erhoben. Barrieren und Förderfaktoren für die Umsetzung der Projekte werden mittels einer Dokumentenanalyse erfasst.

Ergebnisse
Die teilnehmenden und interessierten Kommunen weisen höhere Einwohnerzahlen und geringere Deprivationswerte als der Durchschnitt der Kommunen in Bayern auf und stellen mehr Angebote der Gesundheitsförderung bereit als deprivierte Vergleichskommunen. Großen Einfluss auf die Teilnahme an den Projekten haben finanzielle Faktoren, politische Unterstützung und engagierte Personen.

Diskussion
Die Ergebnisse dieser Studie deuten auf ein Präventionsdilemma auf kommunaler Ebene hin. Um gesundheitlichen Ungleichheiten zwischen Kommunen vorzubeugen, sollten benachteiligte Kommunen in die Gestaltung von Förderprogrammen einbezogen werden, um diese Programme an deren Bedürfnisse anzupassen.
Spatiotemporal Dynamics of the Molecular Expression Pattern and Intercellular Interactions in the Glial Scar Response to Spinal Cord Injury
Authors: Gong Leilei , Gu Yun , Han Xiaoxiao , Luan Chengcheng , Liu Chang , Wang Xinghui , Sun Yufeng , Zheng Mengru , Fang Mengya , Yang Shuhai , Xu Lai , Sun Hualin , Yu Bin , Gu Xiaosong , Zhou Songlin 
Published: July 2022

AbstractNerve regeneration in adult mammalian spinal cord is poor because of the lack of intrinsic regeneration of neurons and extrinsic factors – the glial scar is triggered by injury and inhibits or promotes regeneration. Recent technological advances in spatial transcriptomics (ST) provide a unique opportunity to decipher most genes systematically throughout scar formation, which remains poorly understood. Here, we first constructed the tissue-wide gene expression patterns of mouse spinal cords over the course of scar formation using ST after spinal cord injury from 32 samples. Locally, we profiled gene expression gradients from the leading edge to the core of the scar areas to further understand the scar microenvironment, such as neurotransmitter disorders, activation of the pro-inflammatory response, neurotoxic saturated lipids, angiogenesis, obstructed axon extension, and extracellular structure re-organization. In addition, we described 21 cell transcriptional states during scar formation and delineated the origins, functional diversity, and possible trajectories of subpopulations of fibroblasts, glia, and immune cells. Specifically, we found some regulators in special cell types, such as Thbs1 and Col1a2 in macrophages, CD36 and Postn in fibroblasts, Plxnb2 and Nxpe3 in microglia, Clu in astrocytes, and CD74 in oligodendrocytes. Furthermore, salvianolic acid B, a blood–brain barrier permeation and CD36 inhibitor, was administered after surgery and found to remedy fibrosis. Subsequently, we described the extent of the scar boundary and profiled the bidirectional ligand-receptor interactions at the neighboring cluster boundary, contributing to maintain scar architecture during gliosis and fibrosis, and found that GPR37L1_PSAP, and GPR37_PSAP were the most significant gene-pairs among microglia, fibroblasts, and astrocytes. Last, we quantified the fraction of scar-resident cells and proposed four possible phases of scar formation: macrophage infiltration, proliferation and differentiation of scar-resident cells, scar emergence, and scar stationary. Together, these profiles delineated the spatial heterogeneity of the scar, confirmed the previous concepts about scar architecture, provided some new clues for scar formation, and served as a valuable resource for the treatment of central nervous system injury.
Improving customer satisfaction in proactive service design
Authors: Wenninger Annette , Rau Daniel , Röglinger Maximilian 
Published: July 2022

AbstractAs an emergent variant of digital and smart services, proactive services (PAS) do not wait for customers to make the first move, but proactively participate in customers’ lives and make decisions on their behalf. Due to their novelty, the literature on PAS is in its infancy. Specifically, there is a lack of guidance on designing PAS to meet customer needs. Hence, we examined how customers assess specific features of PAS and whether their assessments differ according to personality traits. To this end, we conducted an online survey via the crowdsourcing platform Prolific, which yielded 259 valid responses. We used a methodological combination of the Kano model, self-stated importance method, and the Five Factor model. Our results reveal that, at the moment, customers do not value features of PAS related to autonomy and that customers engage in paradoxical behavior when assessing the use of personal data. These results allow for a more precise classification and prioritization of the features of PAS tuned to a customer’s most prevalent personality trait.
Research highlights of clinical oncology early 2022
Authors: Wu Kaichun 
Published: July 2022

AbstractAdvance in clinical oncology is highly relied on development of cancer research and clinical trials. There has been ample evidence regarding the new therapeutic drugs, agents or techniques for the treatment of cancer. We did a broad literature search to catch the latest progress in the cancer therapy. Here is a brief review of the newly released results of clinical trials including surgical modalities, immune checkpoint blockade, chimeric antigen receptor T-cell (CAR T) therapy, antibody–drug conjugates and tumor vaccines, etc. Biomarkers or patient assessment of cancer therapy were also discussed.
Periodic Solutions and KAM Tori for the Spatial Maxwell Restricted $$N+1$$-Body Problem with Manev Potential
Authors: Ascencio Mauricio , Vidal Claudio 
Published: July 2022

AbstractWe consider the motion of an infinitesimal mass under the Newtonian attraction of N point masses forming a ring plus a central body where a Manev potential ($$-1/r + e/r^2$$

-
1
/
r
+
e
/

r
2

, $$e \in {\mathbb {R}}$$

e
∈
R

), is applied to the central body. More precisely, the bodies are arranged in a planar ring configuration. This configuration consists of $$N-1$$

N
-
1

primaries of equal mass m located at the vertices of a regular polygon that is rotating on its own plane about its center of mass with a constant angular velocity $$\omega $$
ω
. Another primary of mass $$m_0=\beta m$$

m
0

=
β
m

($$\beta >0$$

β
>
0

parameter) is placed at the center of the ring. Moreover, we assume that the central body may be an ellipsoid, or a radiation source, which introduces a new parameter e. The existence and stability of periodic solutions of the spatial Maxwell restricted $$N+1$$

N
+
1

-body problem is obtained using averaging theory. The determination of KAM 3-tori encasing some of the linearly stable periodic solutions is proved. The planar case is moreover considered.
The Sardauna's Middle East: Regionalism and Backstage Politics in Nigeria's Postcolonial Diplomacy
Authors: Schler Lynn 
Published: July 2022

AbstractThe Middle East conflict has been identified as one of the most polarizing issues in the history of foreign relations of Nigeria during the First Republic (1960–6). The Christian-majority southern regions supported close relations with Israel, while the Muslim-majority Northern Region aligned with Arab states. The Sardauna Ahmadu Bello, Premier of the Northern Region, is remembered as particularly hostile to Israeli incursions in Nigeria. Reviewing new evidence from the Israel State Archives, this article introduces more complexity into portrayals of the Sardauna's positions. Contending with the enormous challenges of decolonization, the Sardauna continually vacillated in his approach to Middle East relations, weighing opportunities against drawbacks in establishing ties. Examining the more accommodating approach that the Sardauna adopted beyond the public eye, we gain new insights into his attempts to achieve political and economic objectives with regard to the Northern Region, while navigating the contentious political landscape of Nigeria's First Republic.
Emergency management plan for paediatric patients with tracheostomies during the coronavirus disease 2019 pandemic
Authors: Petulla B , Ho E , Sov E , Soma M 
Published: July 2022

AbstractObjectivesPaediatric patients with tracheostomies are a vulnerable group. During the coronavirus disease 2019 pandemic, healthcare workers can be anxious about viral transmission from secretions and aerosols emerging from the open airway. This paper aims to share a systematic approach to decrease staff exposure and optimise care of these patients.MethodsThree documents were developed: a generic tracheostomy management plan detailing troubleshooting; a personalised management plan with customised recommendations; and a guide for tracheostomy tube change to minimise aerosol production.ResultsThe plan was distributed to 31 patients (age range, 11 months to 17 years) including 23 (74.2 per cent) with uncuffed tubes and 9 (29 per cent) on long-term ventilation. There have been 10 occasions in which the plan was utilised and influenced management.ConclusionA structured approach to emergency presentations during the coronavirus disease 2019 pandemic may safeguard paediatric patients from unnecessary manipulation of their tracheostomy tube, minimise viral exposure and allow provision of expeditious care.
A hybrid cable-driven parallel robot as a solution to the limited rotational workspace issue
Authors: Ennaiem Ferdaws , Chaker Abdelbadia , Sandoval Juan , Mlika Abdelfattah , Romdhane Lotfi , Bennour Sami , Zeghloul Said , Laribi Med Amine 
Published: July 2022

AbstractCable-driven parallel robots (CDPRs) are still gaining attention thanks to their interesting characteristics compared to serial or classic parallel manipulators. However, the limited range of rotation of their end-effectors reduces their application fields to predominantly translational movements. In this context, the issue of extending the rotational workspace of a CDPR while maintaining a compact robot structure is addressed in this paper. This work is motivated by the need to find the optimal CDPR for upper limb rehabilitation allowing to assist the patient’s hand along a set of prescribed tasks. Firstly, a reconfigurable robot, where the motors’ locations are movable, is proposed in order to help reaching all the prescribed poses. Although this solution presents promising results compared to classical CDPRs, it involves a sizable robot structure inadequate to rehabilitation application. To improve the obtained solution, another approach is proposed, based on combining the large translational workspace of CDPRs and the large rotational workspace of serial manipulators. The optimal structure of a hybrid robot will be considered for the prototype design.
Interlacing China and Taiwan: Tea Production, Chinese-language Education and the Territorial Politics of Re-Sinicization in the Northern Borderlands of Thailand
Authors: Hung Po-Yi 
Published: July 2022

AbstractWhile most ethnic Chinese in northern Thailand are Thai citizens now, their everyday lives are a site where we can witness the political power entanglement of China, Taiwan and Thailand. With this in mind, this paper aims to look into the relationship between global China and overseas Chinese from the perspective of the ethnic Chinese in the northern borderlands of Thailand. The purpose is not just to disclose the multiplicity of global China in people's everyday lives, but also to complicate the picture of overseas Chinese as portrayed in top-down grand narratives about global China. I argue that the ongoing re-Sinicization in South-East Asia and the territorial geopolitics among China, Taiwan and Thailand have opened a conceptual space for the ethnic Chinese in northern Thailand to flexibly articulate themselves within the changing geopolitical economy. I use tea production and related Chinese-language education programmes, two separate but intertwined cases, to address these issues. By looking beyond the competition, conflict and dilemmas between China and Taiwan, I argue that Taiwan's previous engagement with agricultural transfer to Thailand and the rooting of pro-Taiwan identity and discourse in language education have paradoxically paved a way for China to stretch its influence into the everyday lives of the Chinese communities in the northern Thai borderlands.
A Doppler enhanced TDCP algorithm based on terrain adaptive and robust Kalman filter using a stand-alone receiver
Authors: Shao Kefan , Li Zengke , Yang Zhehua , Liu Zan , Sun Yaowen 
Published: July 2022

AbstractTime-differenced carrier phase (TDCP) is a commonly used method of precise velocimetry, but when the receiver is in a dynamic or complex observation environment, the estimation accuracy is reduced. Doppler velocimetry aims at estimating instantaneous velocity, and the accuracy is restricted by the accuracy of measurement. However, in such unfavourable cases, the Doppler measurement is more reliable than the carrier phase measurement. This paper derives the relationship between Doppler observation and TDCP observation, then proposes a Doppler enhanced TDCP algorithm, for the purpose of improving the velocity estimation accuracy in dynamic and complex observation environments. In addition, considering the error caused by the constant speed state update model in the robust Kalman filter (RKF), this paper designs a terrain adaptive and robust Kalman filter (TARKF). After three experimental tests, the improved TDCP algorithm can significantly increase the speed measurement accuracy to sub-metre per second, and the accuracy can be further improved after using TARKF.
Risk factors for underlying comorbidities and complications in patients with hepatitis B virus-related acute-on-chronic liver failure
Authors: Weng Wei-zhen , Chen Jun-feng , Peng Xiao-hua , Huang Miao , Zhang Jing , Xiong Jing , Cao Hui-juan , Lin Bing-liang 
Published: July 2022

Abstract
Hepatitis B virus-related acute-on-chronic liver failure (HBV-ACLF) is a severe and life-threatening complication, characterised by multi-organ failure and high short-term mortality. However, there is limited information on the impact of various comorbidities on HBV-ACLF in a large population. This study aimed to investigate the relationship between comorbidities, complications and mortality. In this retrospective observational study, we identified 2166 cases of HBV-ACLF hospitalised from January 2010 to March 2018. Demographic data from the patients, medical history, treatment, laboratory indices, comorbidities and complications were collected. The mortality rate in our study group was 47.37%. Type 2 diabetes mellitus was the most common comorbidity, followed by alcoholic liver disease. Spontaneous bacterial peritonitis, pneumonia and hepatic encephalopathy (HE) were common in these patients. Diabetes mellitus and hyperthyroidism are risk factors for death within 90 days, together with gastrointestinal bleeding and HE at admission, HE and hepatorenal syndrome during hospitalisation. Knowledge of risk factors can help identify HBV-ACLF patients with a poor prognosis for HBV-ACLF with comorbidities and complications.
Denotational semantics as a foundation for cost recurrence extraction for functional languages
Authors: DANNER NORMAN , LICATA DANIEL R. 
Published: July 2022

Abstract
A standard informal method for analyzing the asymptotic complexity of a program is to extract a recurrence that describes its cost in terms of the size of its input and then to compute a closed-form upper bound on that recurrence. We give a formal account of that method for functional programs in a higher order language with

$\mathtt{let}$

-polymorphism. The method consists of two phases. In the first phase, a monadic translation is performed to extract a cost-annotated version of the original program. In the second phase, the extracted program is interpreted in a model. The key feature of this second phase is that different models describe different notions of size. This plays out in several ways. For example, when analyzing functions that take arguments of inductive types, different notions of size may be appropriate depending on the analysis. When analyzing polymorphic functions, our approach shows that one can formally describe the notion of size of an argument in terms of the data that is common to the notions of size for each type instance of the domain type. We give several examples of different models that formally justify various informal cost analyses to show the applicability of our approach.
Teamwork within a Senior Capstone Course: Implementation and Assessment
Authors: Bayer Reşat , Turper Sedef , Woods Judy 
Published: July 2022

ABSTRACTAlthough senior capstone courses and projects globally are growing in popularity for undergraduate students in political science, with the potential to integrate prior curriculum and assess student learning, students generally undertake this milestone as individuals. In contrast, we present a teamwork-based capstone course wherein key student submissions—including the final project—are created in teams. Having conducted this course for several years, we describe in this article how we incorporated teamwork and demonstrate how students evaluate teamwork in in-person, online, and hybrid course formats.
The Prospective Effect of Cinnamon and Chia on Submandibular Salivary Glands After Ciprofloxacin Administration in Albino Rats (Histological, Histochemical, and Ultrastructural Study)
Authors: Abd-elmonsif Nehad M , El-Zainy Medhat A , Rabea Amany A , Fathy Mohamed Iman A 
Published: July 2022

Abstract
Ciprofloxacin (CPFX®) is potent fluoroquinolone but has severe side effects. Cinnamon (CIN) and chia seeds are potent antioxidants. The current work aimed to compare the effect of CIN extract and chia seeds on CPFX®-treated submandibular salivary glands (SMGs). Thirty-two male albino rats were divided into four groups: Group 1: received saline. Group 2: received CPFX®. Group 3: received CIN extract after 4 h of CPFX® administration. Group 4: received ground chia seeds after 4 h of CPFX® administration. After 10 days, histological, histochemical, and ultrastructural examinations were done. Different examinations illustrated normal features of SMG in Groups 1 and 3. Group 2 showed degenerative signs. Group 4 showed normal features in some areas. Statistical results illustrated that Group 2 had highest mean vacuolation area%. Highest mean of PAS optical density (OD) was for Group 2. Concerning mercuric bromophenol blue stain OD; Group 1 showed highest mean OD. CPFX® has the deteriorative effect on SMG structure and ultrastructure. It leads to increased levels of glycosaminoglycans (GAGs) and decreased levels of total proteins. CIN extract showed more ameliorative effect compared to chia seeds.
Protecting ocean worlds: Europa Clipper planetary protection inputs to a probabilistic risk-based approach
Authors: Smith Alvin L. , Hendrickson Ryan C. 
Published: July 2022

AbstractThere is increased interest in exploring planetary bodies that have ocean worlds, and planetary protection (PP) practices for spacecraft are important to avoid harmful biological contamination of these sensitive environments. In the autumn of 2018 a diverse set of subject matter experts were assembled to examine the environmental input parameters (e.g. space radiation, Europa surface turnover) and biological input parameters that are referenced by the Europa Clipper project probabilistic risk model, to assess the < 1 × 10−4 probability of contamination requirement derived from NASA Procedural Requirements 8020.12D. A joint NASA–JPL lead workshop entitled, ‘Europa Clipper Planetary Protection Workshop’ was convened on 13–15 November 2018, to validate probability model input values, current Europa Clipper PP requirements and implementation strategy, and identify future PP research topics. The three objectives for the 3 day workshop were: (1) to validate the probability of contamination modelling framework for Europa Clipper PP; (2) to agree on probability of contamination model input values, or on a plan to derive/identify appropriate model inputs and (3) to develop workshop concurrence regarding future PP research plans and their priority. Workshop participants engaged in detailed scientific and engineering discussions focusing on Clipper mission objectives and trajectories, Europan ice shell geophysics and understanding the impact of initial microbial bioburdens and spacecraft cleanliness with all three objectives being successfully completed by the end of the workshop.
Catchment Dissolved Organic Carbon Transport: A Modeling Approach Combining Water Travel Times and Reactivity Continuum
Authors: Grandi G. , Bertuzzo E. 
Published: July 2022

AbstractQuantifying the transfer of organic carbon from the terrestrial to the riverine ecosystems is of crucial importance to fully appreciate the carbon cycle at the catchment, regional and global scales. In this study, we propose a framework for modeling the flux of dissolved organic carbon (DOC) from hillslopes to stream and river networks which couples a transport model based on travel time distributions with the reactivity continuum (RC) approach to model DOC degradation. We test the model by applying it to the Plynlimon catchments (UK) exploiting both weekly and high‐frequency (7‐hr interval) time‐series. We use information about chloride to get an independent estimate of water travel times using the framework of StorAge Selection functions. Following the RC model, the composition and the degradation of DOC along the flowpaths, and its consequent concentration in the streamflow, is described assuming that DOC is composed by a mixture of compounds that follows a continuous spectrum of reactivity. For the high‐frequency data set, the model is able to reproduce DOC streamflow concentrations and to capture the complex hysteretic relation between DOC concentration and discharge. Weekly data are instead not frequent enough to properly describe DOC dynamics in this catchment. The distribution of the age of the water comprised in the streamflow proves thus a key variable to predict the quantity and the reactivity of the DOC exported from soils, and the effect of hydrologic variability on this process.