bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of mandibular lingual canal in North Indian population by cone beam computed tomography
Authors: Aggarwal Anshul , Agrawal Neha , Verma Pradhuman , Tewari R K , Gupta Juhi , Goyal Rati 
Published: June 2022

A numerous unnamed accessory canals and foramina have been reported in maxilla and mandible, especially on the lingual aspect, at the midline, lateral to the lingual and mental foramina as well as in the canine–premolar region of the mandible. Given all the potential complications that could arise from an undetected accessory canal, pre-operative radiographs are the standard diagnostic means to rule out such variations. Out of many radiographic techniques, cone beam computed tomographyCBCT) is a suitable diagnostic method for accessory canals of the jaw due to good image quality, excellent geometric accuracy and low radiation exposure to patient. The purpose of this study is to evaluate the frequency and distribution of median lingual canal (MLC) in North Indian population by the use of CBCT. A retrospective analysis of 100 CBCT scans of mandible showing anterior region (51 males and 49 females) of patients from North India; ages ranging from 20- 60 years who visited a diagnostic centre were randomly selected for this study. The CBCT scan evaluation was carried with Carestream 3D software. The frequency and distribution of median lingual canal in anterior region of mandible were evaluated. Two oral and maxillofacial radiologists examined all images to analyze the location median lingual canal with respect to gender and age.Statistical analysis was performed using SPSS software to determine the frequency and distribution of median lingual canal. About 100 patients (male = 51 and female = 49) shows the presence of median lingual canal with prevalence rate of 100%.Only one patient shows three canals. MLC was observed in all 100 cases with prevalence rate of 100%. The study shows the maximum prevalence of two MLC i.e. 60.0% among all. The maximum number of one MLC was present in female cases and maximum number of two MLC was present in male cases. 1MLC was maximum in the age group of 51–60 years, while the 2 MLC and 3 MLC canal was maximum in the age group of 41–50 years of total 100 scans respectively. Statistically, no significant differences were observed in the presence of MLC between gender and among various age groups. The prevalence of MLC near to 100% mandates a thorough radiographic analysis prior to any surgical procedure especially for implant placement in the anterior region of the mandible. A vigilant examination is required using CBCT to avoid post-operative complications.
Prodigious presentation of oral squamous cell carcinoma: early diagnosis and treatment – A case report
Authors: Mehta Mansi , Sorout Ravina , Mehta Deskshe 
Published: June 2022

Squamous cell carcinoma is the most common malignant tumor of the oral cavity and one of the most trivial forms of cancer of the head and neck region It arises from dysplastic oral squamous epithelium. By considering the pathogenesis of squamous cell carcinoma, the smooth and intact surface for this lesion is not usual and almost every time it mimics other inflammatory gingival regions. A solitary well defined proliferative growth of normal mucosal color and sessile in nature. Histopathological examination revealed well differentiated oral squamous cell carcinoma. In this paper, we report an unusual clinical presentation of oral squamous cell carcinoma in buccal mucosa which is very rare.
CHubungan Tingkat Beban Pekerjaan terhadap Kejadian Kifosis pada Buruh Panggul di Pasar Tradisional Tanjung Jember Periode Bulan Januari 2020
Authors: Sutikno Totalenesya Reforrent , Dharmawan Dion Krismashogi , Efendi Erfan 
Published: June 2022

Background: Kyphosis is vertebrae disorder characterized with increased of vertebrae curve in sagital line of 40o Cobb angle. Kyphosis is caused by degenerative proces,, neuromuscular disease, tumor, trauma, congenital abnormalities and unergonomic posture at the moment of carriying weights. One of kyphosis risk factor is excessive weights on the back in long duration. The complication of kyphosis such as vertebrae compression fracture could cause pain and deformities. Objective: Purpose of this research is to describe the correlation between workload level in carrier workers towards kyphosis at Tanjung Market, Jember. Methods: This research was observational analitic, cross sectional method, and total sampling. The respondents were 32 male carrier workers and 32 controls.. Data was obtained by interview and Cobb angle measurement on 1st and 12th thoracal vertebrae using inclinometer. Statistical test was done by Spearman correlation test. Results: The data analysis showed that p value for working time, work tenure, and transport weights toward kyphosis prevalence sequentially were 0,778; 0,326; and 0,739. Male carrier workers in Tanjung Traditional Market used to carry 50-100 Kg of weights once they start to transport. The working time of the carrier workers each day were seven hours and 15 years for work tenure in average. There were two carrier workers (6,2%) suffering of kyphosis (50 years old) with working time 8 hours per day, 10 years for work tenure, and 50 Kg for transport weights.. Conclusion: This research had proven that there is no any correlation between working time, work tenure, and carried load level towards kyphosis in carrier workers of Tanjung Market Jember.
Laporan Kasus : Krisis Hiperglikemi pada Pasien Diabetes Wanita Usia 45 tahun dengan Edema Paru
Authors: Sherliana Ria 
Published: June 2022

Hyperglycemic crisis is a metabolic emergency that causes morbidity or death. Diabetic Ketoacidosis (DKA), and Hyperosmolar Hyperglycemic State (HHS), are 2 forms of hyperglycemic crisis that often occur in patients with uncontrolled diabetes mellitus. A 45-year-old female patient came to the hospital emergency department with decreased consciousness since 12 hours and shortness of breath since 2 days. The patient has a history of diabetes mellitus. On physical examination, E2V2M4 consciousness, blood pressure 140/90, oxygen saturation 40% with a reservoir bag oxygen mask 15 liters per minute, coarse rhonchi and chest retractions. From the results of investigations, there was an increase in blood glucose (523 mg/dL), a chest X-ray of pulmonary edema and bilateral bronchopneumonia. The patient was diagnosed with a hyperglycemic crisis with unstable hemodynamics. However, before being transferred to the intensive care unit, the patient was declared dead. Hyperglycemic crisis is a metabolic emergency whose management must be fast and appropriate in order to maintain hemodynamic stability and prevent death Keyword :Diabetes, Diabetic ketoacidosis, Hyperglycemic crisis, Hyperosmolar hyperglycemic state
Integrasi Nilai Islam dalam Kurikulum Pendidikan Kedokteran
Authors: Susanti Nurlaili , Riskiyah Riskiyah 
Published: June 2022

Background: Medical education has a strategic role in producing professional doctors who will provide quality health services to the community. A medical education curriculum that integrates Islamic content is needed to strengthen professionalism as a Muslim doctor. Objective: This study examines the implementation of Islamic integration in several Islamic Medical Faculties in Indonesia. Methods: This research is qualitative research with a phenomenological approach. The research subject was taken by purposive sampling. The research subjects are the Faculty of Medicine under the State Islamic Religious College (PTKIN). Data collection techniques were carried out through document studies and interviews. Results: Each Faculty of Medicine has the concept of implementing Islamic integration in medical education with different approaches and ways. Conclusion: The implementation of the integration of Islam in medical science is reflected in curriculum development, learning activities, and assessments Keyword :Medical education, muslim doctor, Islamic value, integration, curriculum.
Surgical technologies of sutured iris fixation of the dislocated IOL — fibrosed capsular bag complex
Authors: Nikitin V. N. , Ivanov D. I. 
Published: June 2022

Purpose. To present various techniques of surgical treatment with the dislocation of the IOL — fibrosed capsular bag complex, and to analyze their clinical and functional results.Material and methods. 50 patients (mean age 75.7 ± 1.3 years) who received surgery with IOL-capsular bag complex (ICBC) were divided into 2 groups according to the applied treatment tactics. Tactics 1 consisted in suturing ICBC to the iris on the support needle without manipulations with the capsular bag (26 eyes). Tactic 2 involved IOL suturing to the iris in combination with various manipulations on the capsular bag, aimed at partial or complete removal of fibrous tissue (24 eyes). The follow-up period ranged from 4 to 6 years.Results. The criteria affecting the choice of the treatment technique were determined: integrity of the Zinn ligament, manifestation of capsular bag fibrosis (phimosis of the anterior capsulorhexis, fibrosis of the posterior capsule); impact of changes in the capsular bag structure on the correct position of the IOL (frontal inclination of the IOL, inversion of haptic elements to the optic zone); presence of a prolapse of the vitreous body; Semmering's ring with a high risk of the release of lens masses. A frequency occurrence analysis of the proposed criteria showed their importance in the choice of surgical treatment technique in patients with mixed type ICBC dislocation. Remote functional results of the operations are presented.Conclusion. The proposed low invasive methods of surgical treatment of patients with the dislocation of the IOL — fibrosed capsular bag complex are reliable and technically simple. Relative indications to choosing the treatment method with dislocation of the IOL-fibrosed capsular bag complex have been determined for various combinations of the proposed criteria.
The structure of human retinal vasculature and interstitium in the terminal stage of primary openangle glaucoma
Authors: Bgatova N. P. , Obanina N. A. , Eremina A. V. , Trunov A. N. , Chernykh V. V. 
Published: June 2022

Purpose: to study the structural organization of the vascular bed of human retina in the terminal stage of primary open-angle glaucoma (POAG).Material and methods. We performed a comparative immunohistochemical analysis of the content of vessels in the retina of 13 eyes of patients in the terminal stage of POAG, enucleated for medical reasons, and 17 eyes with uveal melanoma, using the markers of blood vessels endothelium CD34. The ultrastructural organization of the interstitium and endothelial cells of retinal microvessels was studied by electron microscopy and morphometry.Results. A significant increase in the volume density of the interstitium and a decrease in the volume density of CD34+-blood vessels in the retina of patients in the terminal stage of POAG, as compared with uveal melanoma, were revealed. An increased volume density of luminal and basal caveolae and the formation of transendothelial channels in the cytoplasm of endotheliocytes of retinal blood capillaries in the terminal stage of POAG were noted.Conclusion. In the terminal stage of POAG, the interstitial spaces of the retina are increased and the volume density of blood vessels is dropping. The increased volume density of luminal and basal caveolae and the formation of transendothelial channels in the cytoplasm of blood capillary endotheliocytes indicate the growth of transcytosis and the permeability of the blood-retinal barrier.
Ophthalmic hypertension in patients after vitreoretinal surgery with various tamponades of the vitreal cavity
Authors: Akulov S. N. , Kabardina E. V. , Bronnikova N. S. 
Published: June 2022

Purpose. To analyze the cases of ophthalmic hypertension in patients after vitreoretinal surgery with various tamponades of the vitreal cavity. Material and methods. We analyzed 344 case histories of patients aged 30 to 80 who underwent vitreoretinal intervention with various tamponades of the vitreal cavity for macular rupture, epiretinal membrane, hemophthalmia, retinal detachment in 2019–2021. To detect ophthalmic hypertension, all patients underwent tonometry before surgery and every month after it during the entire 2-year follow-up period.Results. Of the 46 patients who were diagnosed with ophthalmic hypertension after vitreoretinal surgery, 18 patients achieved intraocular pressure compensation within the 2 year follow-up and they required no hypotensive therapy. 28 patients, including 4 patients who had glaucoma before vitreoretinal intervention were prescribed hypotensive therapy (carbonic anhydrase inhibitors, 2 adrenomimetics), 2 patients received an implantation of an Express anti-glaucomatous device.Conclusions. The analysis of ophthalmic hypertension in patients after vitreoretinal surgery showed that post-surgical IOP increase occurs both in cases of applying tamponade with silicon oil and those using sterile air or gasair mixture. Intraocular pressure compensation follows different patterns in every case, so that an individual approach is needed. Using one antihypertensive drug may be insufficient so in some cases a stronger antihypertensive therapy is required and sometimes anti-glaucomatous surgical interventions have to be resorted to.
Evaluation of morphometric parameters of the optic disc in patients with diverse clinical forms of openangle glaucoma
Authors: Arutyunyan L. L. , Morozova Yu. S. , Anisimova S. Yu. , Anisimov S. I. 
Published: June 2022

Purpose. To compare the thickness of the prelaminar layer of nerve fibers and the depth of the lamina cribrosa in patients with diverse forms of open-angle glaucoma, measured by optical coherence tomography (OCT).Material and methods. 130 patients aged 71.4 ± 9.7 with stage II (advanced) glaucoma were divided into three groups depending on the form of glaucoma: group 1 of 39 patients with primary openangle glaucoma (POAG); group 2 of 26 patients with normal-tension glaucoma (NTG); group 3 of 22 patients with pseudoexfoliative glaucoma (PEG). The control group consisted of 43 patients without ophthalmic pathology. All patients were scanned for the optic disc and the macular areas in the OCT Disk + Macula 3D regimen and in the Disk Raster regimen (Optopol Revo 60 OCT device (Optopol Technology, Poland). The depth of the lamina cribrosa (LC) and the thickness of the prelaminar layer of nerve fibers (tPLNF) were calculated.Results. No significant differences were found between the LC depth in patients with different forms of glaucoma compared with the control group. LC depth averaged 426.9 ± 98.7 μm (p < 0.164) in patients with POAG, 416.9 ± 161.0 μm (p < 0.818) with NTG and 425.5 ± 88.04 μm, (p < 0.18) with PEG. The thinnest layer of prelaminar nerve fibers was found in patients with NTG (134,0 ± 91.4 μM), where the value was half as much as the control (p < 0.001). There were no differences in the tPNFL parameter in POAG (193.2 ± 114.6 μm) and PEG (190.7 ± 115.3 μm) but both were significantly lower as compared to the control group (p < 0.001, p < 0.002) respectively.Conclusion. The study of LC parameters contributes to a better understanding of the pathogenesis of optic neuropathy in diverse forms of glaucoma. It opens up new opportunities in the differential diagnosis and prediction of the glaucoma course.
Combined surgery for cataract and open-angle glaucoma by a modified technique of partially fistulizing surgery
Authors: Bikbov M. M. , Orenburkina O. I. , Babushkin A. E. , Khusnitdinov I. I. , Israfilova C. Z. 
Published: June 2022

Purpose. To evaluate the clinical and functional results of a combined intervention - one-stage cataract phacoemulsification and a newly developed version of partially fistulizing antiglaucoma surgery (PFS) of patients with primary open-angle glaucoma (POAG) as compared with those of phacoemulsification in combination with penetrating and non-penetrating antiglaucoma intervention.Material and methods. 61 patients (65 eyes) with a combination of incomplete complicated cataract and previously unoperated stages I–III POAG. were divided into 3 groups: group 1 (control, 17 patients, 17 eyes) with ultrasonic cataract phacoemulsification (PEC) and non-penetrating deep sclerectomy (NPDS); 2 group 2 (control, 25 patients, 28 eyes patients with PEC and trabeculectomy (TE); group 3 (main, 19 patients, 20 eyes) with PEC and the newly developed PFS.Results. The best long-term results, with approximately equal hypotensive parameters were achieved with combined operations, which included PEC with TE (the absolute effect achieved in 65% of cases) and PFS (in 60%). However, the number of early postoperative complications after PFS turned out to be almost 2 times as small as after a simultaneous intervention with penetrating TE, and was wholly comparable with that after NPDS (15 and 11.8%). At the same time, the best visual results over the relevant period were observed in the main (0.78 ± 0.06) group and the control group 1 (0.64± 0.05).Conclusion. Combined simultaneous intervention, including cataract phacoemulsification with the newly developed partially fistulizing antiglaucoma surgery, is an effective way to improve visual acuity, normalize intraocular pressure and stabilize glaucomatous optic neuropathy, as well as to reduce the drug load on the patient.
Ocular damages inflicted by criminal injuries
Authors: Gavrilova T. V. , Sobyanin N. A. , Patrushev A. V. , Chereshneva M. V. 
Published: June 2022

Purpose: to analyze eyeball and appendage damages inflicted by criminal injuries of patients who sought assistance by the emergency ophthalmological care unit in Perm.Materials and methods. The data of the patients’register and medical histories of the ophthalmological department of the State Clinical Hospital No. 2 named after Dr. F. H. Gral of Perm for 2018–2020 were retrospectively analyzed.Results. Out of 30428 cases of domestic injuries, 847 (2.8%) were received under criminal circumstances. The victims, predominantly male (77.6%), and of working age (93.7%), were delivered by ambulance in 51.6% of cases. The majority of people sought assistance within 24 hours (90%). The injuries were inflicted by strangers (59.5%) or acquaintances of the patients. 1257 eyes were injured. The prevailing conditions were contusions (46.9%), while the most common traumatizing factor was first punch (79.6%). Combined damages to the eyeball and appendage were more common, claiming 72.6%. Visual acuity fell below 0.1 in 5.6% of cases, 0.1–0.6 in 57.6%, 0.7–1.0 in 36.8% of cases. 45.9% of all cases were represented by eye burns: mainly they were chemical burns (99.5%) of which the overwhelming type was burns caused by gas spray irritants (97.9%). In burn cases, visual acuity was below 0.1 in 1.4% of cases, 0.1–0.6 in 62.6%, 0.7–0.8 in 36% of cases. The wounds inflicted to the eye amounted to 7.2%, the damaging factors being handgun bullet, glass, metallic objects. Injuries of the eyelids and the eyeball were observed. Most of the injuries were mild (91.3%). 5.83% of the victims needed hospitalization in an ophthalmological in-patient facility.Conclusion. The eye trauma, especially one of a criminal nature, is a social problem, and its analysis is highly relevant. The data obtained illustrates the need to increase the general culture of the population, to improve sanitary and educational work, and optimize medical care for those suffered.
An intelligent decision-making system for early diagnosis of macular pathology
Authors: Kamenskikh T. G. , Dolinina O. N. , Kolbenev I. O. , Veselova E. V. 
Published: June 2022

Purpose: to develop a software technology based on artificial intelligence methods aimed at analyzing large volumes of optical coherent tomography (OCT) data in order to identify early symptoms of age-related macular degeneration (AMD) and the transition from dry AMD to neovascular AMD (nAMD).Material and methods. Patients with dry AMD (1125 eyes), wet nAMD (1200 eyes) and subjects without ophthalmic pathology (1205 eyes) underwent a standard ophthalmological examination and macular OCT (Cirrus HD-OCT 4000, Carl Zeiss Meditec AG, Germany) according to the MacularCube scanning protocol with a standard ETDRS macular map. The thickness of the retina from the inner limiting membrane to the retinal pigment epithelium and the presence and location of fovea configuration changes were determined.Results. Two ultra-precise artificial neural networks (ANN) were created: one intended to identify patients with early signs of dry AMD and the other to identify those with signs of nAMD. By the time when 1000 training images were processed, the image interpretation decision-making accuracy in the first ANN increased to reach 97.6%, in the second ANN, to 96.8%, which shows the high efficiency of this technology. The deep learning processes were run on an Amazon Web Service EC2 GPU. The trained ANN model was also tested on healthy eyes at each estimated probability value. The correspondence between the doctor's diagnosis and the decision taken by the ANN was assessed.Conclusions. A software technology based on artificial intelligence methods has been developed, which answered the need to process a large amount of OCT data. The technology proved effective in identifying early symptoms of dry and wet forms of AMD and in early diagnosis of the transition of the dry form of AMD into neovascular form, the latter requiring immediate treatment.
A clinical and functional system for patients with accommodation disorders subjected to excimer laser correction of hypermetropia
Authors: Kuznetsova O. S. , Balalin S. V. 
Published: June 2022

Purpose: to develop a clinical and functional rehabilitation system for patients with mild and moderate hyperopia and accommodation disorders before and after FemtoLASIK surgery and to assess its effectiveness.Material and methods. 234 patients (234 eyes) with the above conditions, aged 25 to 30 (mean age 27.9 ± 1.2 years) were divided into 2 groups. The control group included 114 patients (114 eyes) who received no prevention measures or accommodation disorders treatment, while the main group (120 patients, 120 eyes) received clinical and functional rehabilitation before and after FemtoLASIK.Results. The “false myopization” syndrome observed in the main group was 14.2% lower than in the control group. A week after FemtoLASIK, the normalization of accommodation parameters was achieved in 57.5% of the main group cases, and combined accommodation disorders occurred 2.37 less frequently than in the control group. Weak accommodation in patients of this group was 30% less than in the control group. Habitually excessive accommodation in the control group was 2.45 times more frequent than in the main group. According to the CISS test questionnaire, the mean values of indices for the main group patients reached the normal level one month after FemtoLASIK whilst the control group required 6 months.Conclusion. The clinical and functional rehabilitation system in patients with mild and moderate hyperopia and accommodation disorders applied before and after FemtoLASIK helps achieve maximum clinical and functional results 1 month after the operation and yields the best results in accommodation disorders treatment.