bluuebunny/crossref_metadata_2025_split huggingface dataset:
SEMANTIC ANALYSIS; JARGON AND WORDS WITH SPECIFIC MEANING USED IN MOTOGP
Authors: Fayi Thifal , Rejeki Sari , Widisanti Ni Made 
Published: June 2022

This study aims to identify the jargon and specific meaning used by the professionals and community of MotoGP such as commentators and hosts (during MotoGP race), interviewers (during interviews) and racers (during interviews) taken from YouTube in the period of March-November 2019. This research is descriptive-qualitative in nature. The results of the study reveal, out of 64, 33 words are categorized as jargons and 31 words have specific meaning. The jargon and words which specific meaning found in the sport of MotoGP racing all refer to the racing technique, the situation and conditions of the riders, the communication between the teams and groups of the event, as well as the conditions of the race track in competitions. Keywords : Jargon; specific meaning; MotoGP
Representasi Yami Kawaii Pada Kondisi Kejiwaan Anak-Anak Muda Di Jepang
Authors: Larasati Putu Vergenia Ayu , Fitriana Rina , Winny Paramita 
Published: June 2022

Abstrak Di dalam skripsi ini membahas mengenai Representasi Yami kawaii pada kondisi kejiwaan anak-anak muda di Jepang. Penelitian ini dilaksanakan untuk menunjukan kepopuleran Yami kawaii yang akhir-akhir ini sering dibicarakan oleh masyarakat Jepang, khususnya anak-anak muda di Jepang yang tertarik dengan berbagai tren fesyen dan lain-lain. Diharapkan pada penelitian ini agar pembaca dapat menambah kewawasannya mengenai sub tren fesyen terbaru dari gaya Harajuku, yang akhir-akhir ini telah menjadi booming, khususnya di dunia perfesyenan di Jepang. Harajuku memang merupakan jalanan yang paling terkenal dengan kontras warna-warni keberagaman fesyennya. Namun, bagaimana jika gaya tersebut dipadukan dengan konteks kehidupan secara realita. Yami kawaii atau menhera-kei, merupakan sebuah tren yang lahir dari kesan bold dan wild yang sangat melekat di jalanan Harajuku ini. Ketika bagian dari konteks kehidupan nyata meresap ke dalam gaya kawaii atau ketika orang-orang ingin memproyeksikan perasaan mereka, terutama perasaan sedih, sesak, dan sakit, maka tren Yami kawaii muncul di hadapan itu semua. Dalam penelitian ini penulis menggunakan metode penelitian deskriptif, yang meneliti tentang fenomena-fenomena yang terjadi, secara aktual pada gejala-gejala yang telah terjadi, khususnya pada tren Yami kawaii yang dapat dihubungkan dengan kondisi kejiwaan anak-anak muda di Jepang. Dengan menggunakan teknik kajian pustaka, yaitu mengumpulakan sejumlah data-data baik dari literatur dan berbagai sumber artikel dari internet yang berkaitan dengan judul yang penulis teliti. Kata kunci: Yami kawaii, menhera-kei, anak-anak muda di Jepang, kondisi kejiwaan, tren fesyen, Harajuku
Analisis Unsur Surealisme dalam Novel Umibe no Kafuka Karya Murakami Haruki
Authors: Kurniadewi Trifa Fajarina , Fitriana Rina , Haryati Tatat 
Published: June 2022

Abstrak Penelitian ini membahas unsur surealisme yang terdapat pada tokoh dan latar serta proses pembentukan identitas tokoh utama Kafka Tamura dalamnovel Umibe no Kafuka. Metode yang digunakan adalah deskriptif analisis. Teori yang digunakan meliputi tokoh dan penokohan, latar, surealisme dan psikoanalisis Jacques Lacan. Hasil analisis yang diperoleh adalah unsur surealisme yang terdapat pada sifat dan perilaku tokoh serta latar merupakan pengaruh dari proses pembentukan identitas tokoh utama. Proses pembentukan identitas maupun unsur surealisme, keduanya dibentuk oleh alam sadar manusia.Kata Kunci : surealisme, psikoanalisis, alam bawah sadar, identitas
PENGARUH KESADARAN MEREK TERHADAP KEPUTUSAN PEMBELIAN DALAM PENGGUNAAN E-COMMERCE TRAVELOKA (Kasus Di Kelurahan Baranangsiang Bogor Timur)
Authors: Wajdi Fahmi Indra , Martha Layung Paramesti , Kusumaningtias Intan Tri 
Published: June 2022

The aims of this study are determine the level of awareness of the Kelurahaan Baranangsiang community brand and to find out how the level of brand awareness influences the community purchasing decisions of Baranangsing Village towards Traveloka E-commerce. The method used in this study was descriptive quantitative using survey research. This research was conducted in Kelurahaan Baranangsiang, East Bogor District, Bogor City with a total of 100 respondents. The sampling technique used in this study is a non probability sampling technique with a purposive sampling method. Quantitative data is presented in the form of a frequency table. Statistical tests were carried out with the help of the SPSS version 25.0 program. Based on the results of the study, it was found that the level of brand awareness of the Baranangsiang Kelurahan community was dominated by people with brand awareness at the brand recognition level. It can be concluded that brand awareness has an influence but the influence given is not too significant. But at the peak level of mind towards the level of awareness of the Traveloka brand weakening, which shows that the peak of one's mind can change along with the development of E-commerce that exists today. Keywords: E-Commerce, Traveloka, Brand Awareness Level, Purchasing Decision.
ANALISIS MANAJEMEN KOMUNIKASI DISKOMINFOSTANDI DALAM MENINGKATKAN KUALITAS PELAYANAN PEMKOT BOGOR (STUDI KASUS APLIKASI SI BADRA)
Authors: Sabilah Danil , Puspanidra Tiara , Martha Layung Paramesti 
Published: June 2022

This study aims to describe how the communication management carried out by DISKOMINFOSTANDI in an effort to improve service quality through the Si Badra Application program. This research is a used of descriptive qualitative research methods. Data collection techniques through interviews, observation and documentation. The results showed that the communication management process carried out consisted of four stages, namely the analysis, planning, implementation, and control stages. In this stage DISKOMINFOSTANDI was less prepared in the implementation process, namely the training carried out. But it is very good in the other processes.
Gentamicin Augments the Quorum Quenching Potential of Cinnamaldehyde In Vitro and Protects Caenorhabditis elegans From Pseudomonas aeruginosa Infection
Authors: Chadha Jatin , Ravi  , Singh Jogender , Chhibber Sanjay , Harjai Kusum 
Published: June 2022

The quorum sensing (QS) circuitry of Pseudomonas aeruginosa represents an attractive target to attenuate bacterial virulence and antibiotic resistance. In this context, phytochemicals harboring anti-virulent properties have emerged as an alternative medicine to combat pseudomonal infections. Hence, this study was undertaken to investigate the synergistic effects and quorum quenching (QQ) potential of cinnamaldehyde (CiNN) in combination with gentamicin (GeN) against P. aeruginosa. The QQ activity of this novel combination was evaluated using a QS reporter strain and synergism was studied using chequerboard assays. Further, the genotypic and phenotypic expression of pseudomonal virulence factors was examined alongside biofilm formation. The combination of CiNN and GeN exhibited synergy and promising anti-QS activity. This drug combination was shown to suppress AHL production and downregulate the expression of critical QS genes in P. aeruginosa PAO1. Molecular docking revealed strong interactions between the QS receptors and CiNN, asserting its QQ potential. Bacterial motility was compromised along with a significant reduction in pyocyanin (72.3%), alginate (58.7%), rhamnolipid (33.6%), hemolysin (82.6%), protease (70.9%), and elastase (63.9%) production. The drug combination successfully eradicated preformed biofilms and inhibited biofilm formation by abrogating EPS production. Our findings suggest that although GeN alone could not attenuate QS, but was able to augment the anti-QS potential of CiNN. To validate our results using an infection model, we quantified the survival rates of Caenorhabditis elegans following PAO1 challenge. The combination significantly rescued C. elegans from PAO1 infection and improved its survival rate by 54% at 96 h. In summary, this study is the first to elucidate the mechanism behind the QQ prospects of CiNN (augmented in presence of GeN) by abrogating AHL production and increasing the survival rate of C. elegans, thereby highlighting its anti-virulent properties.
Genomic Characterization of Mutli-Drug Resistant Pseudomonas aeruginosa Clinical Isolates: Evaluation and Determination of Ceftolozane/Tazobactam Activity and Resistance Mechanisms
Authors: Bitar Ibrahim , Salloum Tamara , Merhi Georgi , Hrabak Jaroslav , Araj George F. , Tokajian Sima 
Published: June 2022

Resistance to ceftolozane/tazobactam (C/T) in Pseudomonas aeruginosa is a health concern. In this study, we conducted a whole-genome-based molecular characterization to correlate resistance patterns and β-lactamases with C/T resistance among multi-drug resistant P. aeruginosa clinical isolates. Resistance profiles for 25 P. aeruginosa clinical isolates were examined using disk diffusion assay. Minimal inhibitory concentrations (MIC) for C/T were determined by broth microdilution. Whole-genome sequencing was used to check for antimicrobial resistance determinants and reveal their genetic context. The clonal relatedness was evaluated using MLST, PFGE, and serotyping. All the isolates were resistant to C/T. At least two β-lactamases were detected in each with the blaOXA-4, blaOXA-10, blaOXA-50, and blaOXA-395 being the most common. blaIMP-15, blaNDM-1, or blaVIM-2, metallo-β-lactamases, were associated with C/T MIC &gt;256 μg/mL. Eight AmpC variants were identified, and PDC-3 was the most common. We also determined the clonal relatedness of the isolates and showed that they grouped into 11 sequence types (STs) some corresponding to widespread clonal complexes (ST111, ST233, and ST357). C/T resistance was likely driven by the acquired OXA β-lactamases such as OXA-10, and OXA-50, ESBLs GES-1, GES-15, and VEB-1, and metallo- β-lactamases IMP-15, NDM-1, and VIM-2. Collectively, our results revealed C/T resistance determinants and patterns in multi-drug resistant P. aeruginosa clinical isolates. Surveillance programs should be implemented and maintained to better track and define resistance mechanisms and how they accumulate and interact.
Septal Thickness Does Not Impact Outcome After Hypertrophic Obstructive Cardiomyopathy Surgery (Septal Myectomy and Subvalvular Mitral Apparatus Remodeling): A 15-Years of Experience
Authors: Raffa Giuseppe M. , Franca Eluisa La , Lachina Carlo , Palmeri Andrea , Kowalewski Mariusz , Lebowitz Steven , Ricasoli Alessandro , Greco Matteo , Sciacca Sergio , Turrisi Marco , Morsolini Marco , Stringi Vincenzo , Mattiucci Gabriella , Pilato Michele 
Published: June 2022

BackgroundThe aim of this study was to assess the impact of septal thickness on long-term outcomes of surgical treatment for hypertrophic obstructive cardiomyopathy (HOCM) and correction of mitral subvalvular anomalies.MethodsSixty-six consecutive patients (58 ± 12 years, 56% female) undergoing extended septal myectomy and subvalvular mitral apparatus remodeling from 2007 to 2021 were retrospectively reviewed. Patients were divided into 2 groups according to septal thickness: moderate [&lt; 18 mm, 29 patients (44%)] and severe [≥ 18 mm, 37 patients (56%)]. End points included survival, symptom improvement, reduction of left ventricle outflow tract (LVOT) gradient, resolution of mitral regurgitation (MR), and reoperation.ResultsThe mean interventricular septal thickness was 19 ± 3 mm, 15.8 ± 0.8 mm in patients with moderate and 21.4 ± 3.2 mm in those with severe hypertrophy. Preoperative data, intraoperative variables, postoperative complication rates, pre-discharge echocardiographic and clinical parameters did not differ between the two study groups [except for procedures involving the posterior mitral leaflet (p = 0.033) and septal thickness after myectomy (p = 0.0001)]. Subvalvular apparatus remodeling (secondary chordae of mitral valve resection and papillary muscle and muscularis trabecula procedures including resection, splitting, and elongation) was invariably added to septal myectomy (100%). Four (6%) procedures involved the posterior mitral leaflets. Mitral valve replacement was carried out in two patients (3%, p = 0.4). Reoperation for persistent MR was necessary in one patient (1%, p = 0.4). Neither iatrogenic ventricular septal defect nor in-hospital mortality occurred. During follow-up (mean 4.8 ± 3.8 years), two deaths occurred. NYHA class was reduced from 2.9 ± 0.7 to 1.6 ± 0.6 (p &lt; 0.0001), the LVOT gradient from 89.7 ± 34.5 to 16.3 ± 8.8 mmHg (p &lt; 0.0001), mitral valve regurgitation grade from 2.5 ± 1 to 1.2 ± 0.5 (p &lt; 0.0001), and septal thickness from 18.9 ± 3.7 to 13.9 ± 2.7 mm (p &lt; 0.0001).ConclusionsRegardless of septal thickness, subvalvular apparatus remodeling with concomitant septal myectomy can provide satisfactory long-term outcomes in terms of symptom improvement, LVOT obstruction relief, and MR resolution (without mitral valve replacement in most cases) in patients with HOCM.
Assessing Causal Associations of Atopic Dermatitis With Heart Failure and Other Cardiovascular Outcomes: A Mendelian Randomization Study
Authors: Chen Heng , Zhuo Chengui , Zheng Liangrong 
Published: June 2022

Background and AimsObservational epidemiological studies have suggested that atopic dermatitis (AD) was associated with an increased risk of cardiovascular diseases (CVDs). However, causality remains to be established. In the present study, Mendelian randomization (MR) analyses were used to evaluate whether AD and CVDs are causally associated.MethodsThis study was based on summary statistics of genome-wide association studies (GWASs) for a set of cardiovascular outcomes including heart failure (HF), coronary artery disease (CAD), myocardial infarction (MI), atrial fibrillation (AF), stroke, and stroke subtypes. A total of 19 independent single nucleotide polymorphisms associated with AD were identified at a genome-wide significance threshold (P &lt; 5 × 10−8) based on a large GWAS meta-analysis. MR estimates were pooled using the inverse variance weighted method. Complementary analyses further evaluated the robustness of the results.ResultsGenetically determined AD was causally associated with HF [odds ratio (OR), 1.07; 95% confidence interval (CI), 1.03–1.10; P = 1.11 × 10−4]. However, there was no causal association between AD and the risk of AF, CAD, MI, stroke, and stroke subtypes. Complementary analyses returned similar results. No horizontal pleiotropy was found.ConclusionThis MR study provided evidence to support that AD exerted an effect contributing to HF. No significant associations were found for other cardiovascular outcomes. The study suggested that prevention and early diagnosis of AD may help prevent HF. Improved awareness of these associations is warranted for better management of CVDs in the future.
Robust Association Between Changes in Coronary Flow Capacity Following Percutaneous Coronary Intervention and Vessel-Oriented Outcomes and the Implication for Clinical Practice
Authors: Hamaya Rikuta , Yonetsu Taishi , Sayama Kodai , Matsuda Kazuki , Ueno Hiroki , Nagamine Tatsuhiro , Misawa Toru , Hada Masahiro , Hoshino Masahiro , Sugiyama Tomoyo , Sasano Tetsuo , Kakuta Tsunekazu 
Published: June 2022

BackgroundCoronary flow capacity (CFC) is a potentially important physiologic marker of ischemia for guiding percutaneous coronary intervention (PCI) indication, while the changes through PCI have not been investigated.ObjectivesTo assess the determinants and prognostic implication of delta CFC, defined as the change in the CFC status following PCI.Materials and MethodsFrom a single-center registry, a total of 450 patients with chronic coronary syndrome (CCS) who underwent fractional flow reserve (FFR)-guided PCI with pre-/post-PCI invasive coronary physiological assessments were included. Associations between PCI-related changes in thermodilution method-derived CFC categories and incident target vessel failure (TVF) were assessed.ResultsThe mean (SD) age was 67.1 (10.0) years and there were 75 (16.7%) women. Compared with patients showing no change in CFC categories after PCI, patients with category worsened, +1, +2, and +3 category improved had the hazard ratio (95% CI) for incident TVF of 2.27 (0.95, 5.43), 0.85 (0.33, 2.22), 0.45 (0.12, 1.63), and 0.14 (0.016, 1.30), respectively (p for linear trends = 0.0051). After adjustment for confounders, one additional change in CFC status was associated with 0.61 (0.45, 0.83) times the hazard of TVF. CFC changes were largely predicted by the pre-PCI CFC status.ConclusionCoronary flow capacity changes following PCI, which was largely determined by the pre-PCI CFC status, were associated with the lower risk of incident TVF in patients with CCS who underwent PCI. The CFC changes provide a mechanistic explanation on potential favorable effect of PCI on reducing vessel-oriented outcome in lesions with reduced CFC and low FFR.
Relationships Between Rapid Urbanization and Extreme Summer Precipitation Over the Sichuan–Chongqing Area of China
Authors: Wang Hao , Yan Yilin , Long Keji , Chen Qingqing , Fan Xingang , Zhang Fugui , Tan Linyin 
Published: June 2022

China has undergone rapid urbanization over the past few decades, and accordingly, changes have occurred in the extreme precipitation events. However, few studies have focused on the relationships between rapid urbanization and extreme precipitation events in southwest China, particularly in the Sichuan–Chongqing area, which has a complex topography and has experienced rapid urbanization over the past few decades. This is the first study to analyze the impact of urbanization on the amount, frequency, and intensity of extreme summer (June–August) precipitation events over the past 30 years. Our results indicate that extreme precipitation events primarily occurred in the urban-dominated Sichuan basin, particularly during the fast urbanization development stage (FUDS) of 1994–2015. Extreme precipitation amounts and intensities increased during the FUDS, implying the greater probability of individual precipitation events developing into heavy or extreme events in a particular area. In addition, the probability distribution functions of the occurrence and volume of strong convective events significantly increased during the FUDS. Finally, the annual increase in urban-scale land surface air temperature, increase in wet convection, and changes in wind speed are identified as essential factors leading to extreme precipitation events in this region.
Influence of Dietary Salt Intake on T2D Treatment
Authors: Li Li , Mi Yuwei , Xu Miao , Ruan Liemin , Sun Jie , Song Qifa 
Published: June 2022

BackgroundsTo what extent patients undergoing long-term T2D treatment are affected by dietary salt intake has not been completely investigated.ObjectivesWe aimed to investigate the influence of dietary salt intakes on T2D treatment, including glucose-lowering effect and indices related to T2D progression.MethodsThe study recruited 1090 patients with T2D at Ningbo City First Hospital from January 1, 2018, to December 30, 2021. We compared their one-year follow-up outcomes in terms of fasting blood glucose (FBG), glycated hemoglobin (HbA1c), blood pressure, obesity, and prevalence of retinopathy and neuropathy among groups with different dietary salt intakes.ResultsThe 1090 patients consisted of 287(26.3%) decreasing-, 190(17.4%) increasing-, 175(16.0%) steadily low-, 243(22.3%) steadily medium-, and 195(17.9%) steadily high-dietary salt intake patients. Compared to increasing-, steadily medium-, and steadily high-dietary salt intake patients, decreasing and steadily low salt intake led to lower baseline FBG, HbA1c, systolic blood pressure (SBP), BMI, and visceral fat area (VFA) (all p&lt;0.05), to a larger decrease in FBG, HbA1c, SBP, BMI, and VFA after one-year treatment (all p&lt;0.05), as well as to a slightly lower prevalence of retinopathy and a significantly lower prevalence of neuropathy. The steadily low salt patients had lower urine albumin/creatinine ratio (UAR) both at baseline and after treatment. Notably, the fasting insulin in the steadily low salt group was higher than the remaining groups after treatment (p&lt;0.01).ConclusionsThe present study concludes that lowered dietary salt intake benefits T2D treatment in multiple aspects, including main treatment targets such as FBG and HbA1c, and indices reflecting potential complications of T2D, including BMI, VFA, SBP, UAR, retinopathy, and neuropathy.Clinical Trial Registrationwww.ClinicalTrials.gov, identifier: NCT03811470.
Techno-Economic and Environmental Assessment of Ammonia Production From Residual Bagasse Gasification: A Decarbonization Pathway for Nitrogen Fertilizers
Authors: Telini Rodrigo Oliveira , Flórez-Orrego Daniel , de Oliveira Junior Silvio 
Published: June 2022

This work evaluates the potential to produce synthetic nitrogen fertilizers by using sugarcane bagasse gasification in the São Paulo state, Brazil, aiming to increase the economic revenues and to decarbonize a chemical sector traditionally based on natural gas. The partial or total substitution of natural gas by consuming bagasse and enabling an intensive import of electricity from the Brazilian electricity mix is studied. The comparative assessment of the alternative production routes considers a reference case in which the residual bagasse is used only to generate surplus power at the cogeneration unit of the sugarcane mill, whereas ammonia is typically produced by consuming only natural gas. Unlike the conventional scenario, the proposed alternative routes employ surplus bagasse to produce ammonia. Regarding the unit exergy cost of ammonia, an increase between 50% and 100% is expected for the biomass-based routes (2.4498–3.1780 kJ/kJNH3) when compared to the conventional case (1.5866 kJ/kJNH3). In contrast, the net CO2 emissions balance of the alternative scenario achieve negative values (−2.5017 tCO2/tNH3), in comparison to the net CO2 positive emissions (1.75 tCO2/tNH3) of the conventional scenario. Additionally, the best location of the ammonia plant is nearby a sugarcane mill with a milling capacity of 10 Mt/y and 20 km far from another smaller sugarcane mill, in order to achieve an ammonia production potential of 1,200 tNH3/day. Concerning the economic analysis, if no carbon taxes are considered, the net present value (NPV) of the alternative scenarios drops up to 52%, compared to the conventional scenario. Finally, since 1.6 MtCO2/y can be avoided by using the residual bagasse as feedstock in the ammonia plant, the alternative scenarios become competitive vis-à-vis the conventional scenario in terms of NPV when carbon taxes of 40–50 USD/tCO2 are adopted. In the absence of carbon taxes, the drawback of the seasonality of the sugarcane crops (240 days of operation compared to 340 days for the conventional scenario) contributes to the decrease (39%–51%) of the NPV for the alternative scenarios.