bluuebunny/crossref_metadata_2025_split huggingface dataset:
Concept and Dependencies Enhanced Graph Convolutional Networks for Short Text Classification
Authors: Zhang Hu , Bai Ping , Li Ru 
Published: June 2022

Abstract
Short text classification task is a special kind of text classification task in that the text to be classified is generally short, typically generating a sparse text representation that lacks rich semantic information. Given this shortcoming, scholars worldwide have explored improved short text classification methods based on deep learning. However, existing methods cannot effectively use concept knowledge and long-distance word dependencies. Therefore, based on graph neural networks from the perspective of text composition, we propose concept and dependencies enhanced graph convolutional networks for short text classification. First, the co-occurrence relationship between words, the inclusion relationship between documents and words, long-distance word dependencies, and the association relationship between external concepts and words are defined. Then, a text graph is constructed for an entire text corpus based on the four relationships. Finally, the text graph is input into graph convolutional neural networks, and the category of each document node is predicted after two layers of convolution. Experimental results show that our proposed method overall best on multiple classical English text classification datasets.
A Digital Twin of Synchronized Circular Laser Array for Powder Bed Fusion Additive Manufacturing
Authors: Attariani Hamed , Petitjean Shayna Renay , Dousti Majid 
Published: June 2022

Abstract
The formation of undesirable microstructures and defects hinders the widespread use of additive manufacturing, e.g., the formation of columnar grains in Ti-6Al-4V leads to undesirable anisotropic mechanical properties. Here, the microstructure produced by a novel synchronized circular laser array for application in the powder bed fusion technique is investigated. The temporal temperature distribution for different process parameters (laser power, scanning speed, and internal distance between lasers in the array) were obtained by an anisotropic heat transfer model, and the Hunt criterion was employed to construct the solidification map. The results revealed that a degree of overlap between lasers is recommended to form a coherent melt pool, avoid degeneracy in surface quality, and maintain adequate resolution for all processing windows. However, laser overlap is not required for low scanning speed and high power scenarios. Finally, microstructure prediction shows that 45% of printed track includes equiaxed grains at a high power regime (500 W). However, the volume fraction of the equiaxed microstructure is reduced by decreasing laser power.
What is the impact of endometrioma on IVF/ICSI outcomes in patients with endometriosis: A retrospective study
Authors: Chang Jui-Chun , Yi Yu-Chiao , Chen Ya-Fang , Guu Hwa-Fen , Kung Hsiao-Fan , Chen Li-Yu , Chuan Shih-Ting , Chen Ming-Jer 
Published: June 2022

Abstract
Background
Does endometrioma per se, different from endometriosis, have specific impacts on IVF/ICSI outcomes? Dose cystectomy of the endometrioma improve IVF/ICSI outcomes?
Methods
We retrospectively analyzed 2153 IVF/ICSI cases treated during Jan/01/2014 to Dec/31/2020 in VGHTC. Two-hundred-and-eight women receiving IVF/ICSI treatment due to endometriosis. The control group consisted of 624 infertile women without endometriosis. First, we divided 208 patients into those with endometrioma (89) and those only with endometriosis (119). Second, we divided patients into primary endometrioma, recurrent endometrioma and those having received cystectomy for endometrioma before IVF/ICSI. Reproductive outcomes were compared.
Results
We found in the endometrioma subgroup (B), the usage gonadotropin dose was significantly higher, and the blastocyst formation rate was significantly lower compared with endometriosis (A) and control group (C). The CLBR (60.5% versus 49.4% versus 56.9%, p = 0.194 in A versus B, p = 0.406 in A versus C, p = 0.878 in B versus C) were comparable. From the second analysis, the blastocyst formation rate was significantly higher in the s/p cystectomy group. The CLBR were comparable (47.1%, 60% and 57.9% p = 0.194 in D versus E, p = 0.406 in D versus F, p = 0.878 in E versus F, in primary endometrioma (D), s/p cystectomy (E) and recurrent endometrioma group (F)).
Conclusions
Although the blastocyst formation rate was lower, and the usage gonadotropin dose was higher in the endometrioma group, CLBR was not worse than those with endometriosis or control. Cystectomy for endometrioma did not alter IVF/ICSI outcomes if ovarian reserve is comparable. Recurrent endometrioma did not worsen ART outcome than primary endometrioma.
Appropriate management of Kawasaki disease patients with coronary artery aneurysms: an interim report on a multicentric prospective registry study three years after commencement
Authors: Koyama Yutaro , Miura Masaru , Kobayashi Tohru , Hokosaki Tatsunori , Suganuma Eisuke , Numano Fujito , Furuno Kenji , Shiono Junko , Ebata Ryota , Fuse Shigeto , Fukazawa Ryuji , Mitani Yoshihide 
Published: June 2022

Abstract
The remote prognosis of patients with Kawasaki disease (KD) complicated by coronary artery aneurysms (CAA) is still unclear. The present, multicentric registry study aimed to study the factors associated with coronary events (CE) and determine an appropriate management method for patients with KD complicated with medium-sized or large CAA from 2015 to the present. The primary endpoint was the time-dependent incidence of CE. Associated factors were also examined. In total, 179 patients from 53 centers were enrolled and followed up for a median of 501 days. The median age at KD onset was 2.2 years, 137 patients were male (77%), 47 had incomplete KD (26%), and 36 had large CAA (20%). CE occurred in 13 patients (7%; 95% confidence interval: 4-12%); eight (62%) experienced CE within one year, and all the patients experienced a CE within two years. All but one patient received antiplatelet drugs and warfarin. Patients with a large CAA had significantly more CAA (2.8 vs. 1.7, p < 0.001), more cases of warfarin use (86% vs. 43%, p < 0.001), and were more likely to have CE (28% vs. 2%, p < 0.001) than those with a medium-sized CAA. On Cox proportional hazards analysis, the factors significantly associated with CE were large CAA (hazard ratio (HR): 17.0), three or more CAA (HR: 23.3), and beaded CAA (HR: 15.9).Conclusion: Patients with a large CAA were more likely to have a CE within two years, suggesting that antithrombotic therapy with warfarin may have limited efficacy. Patients with multiple or beaded CAA should be managed carefully.
Clinical sequencing identifies potential actionable alterations in a high rate of urachal and primary bladder adenocarcinomas
Authors: Varadi Melinda , Nagy Nikolett , Reis Henning , Hadaschik Boris , Niedworok Christian , Modos Orsolya , Szendroi Attila , Ablat Jason , Black Peter , Keresztes David , Csizmarik Anita , Olah Csilla , Gaisa Nadine , Kiss András , Tímár József , Toth Erika , Csernák Erzsébet , Gerstner Arpad , Mittal Vinay , Karkampouna Sofia , de Julio Marianna Kruithof , Gyorffy Balazs , Bedics Gabor , Rink Michael , Fisch Margit , Nyirády Peter , Szarvas Tibor 
Published: June 2022

Abstract
Administration of targeted therapies provides a promising treatment strategy for rare cancers such as urachal adenocarcinoma (UrC) or primary bladder adenocarcinoma (PBAC), however, the selection of appropriate drugs remains difficult. Therefore, in the present study, we aimed to establish a routine compatible methodological pipeline for the identification of the most important therapeutic targets and potentially effective drugs for UrC and PBAC. Next-generation sequencing using a 161 cancer driver gene panel was performed on 41 UrC and 13 PBAC samples. Clinically relevant alterations were filtered by four publicly available databases. Therapeutic interpretation has been performed by in silico evaluation of drug-gene interactions using an evidence-based decision support tool. After data processing, 45/54 samples (33 UrC and 12 PBAC) passed the quality control. The sequencing analyses revealed a total of 191 pathogenic SNVs in 68 genes. The most frequent gain-of-function mutations in UrC were found in KRAS (33%), MYC (15%), EGFR (9%) and ERBB2 (9%), while in PBAC KRAS (25%), MYC (25%), FLT3 (17%) and TERT (17%) were recurrently affected. The most frequently affected pathways in both tumour types were related to cell cycle regulation, DNA damage control and the MAPK/RAS pathway. Actionable mutations with at least one available, regulatory agency-approved drug could be identified for 31/33 (94%) of UrC and 8/12 (67%) of PBAC patients. In this study, we used a commercially available assay and developed a data processing pipeline for the detection and therapeutic interpretation of genetic alterations in two rare cancers. Our analyses revealed actionable mutations in a high rate of cases, including EGFR, BRCA, CCND1/2/3, ERBB2, METex14 suggesting a potentially feasible strategy for both UrC and PBAC treatment.
Effect of Annealing on Thermal and Dynamic Mechanical Properties of Poly(lactic acid)
Authors: Zennaki Assia , Zair Latifa , Arabeche Khadidja , Benkraled Lina , Maschke Ulrich , Berrayah Abdelkader 
Published: June 2022

Abstract
Effects of annealing temperature (Ta: 80-140°C) and time (ta: 3-30 h) on the crystalline phase transition in poly(lactic acid) (PLA) were studied by Differential Scanning Calorimetry (DSC) and Dynamic Mechanical Analysis (DMA). In the DSC curves, the sample annealed at Ta=80°C with time interval (ta: 10-30 h) demonstrates a peculiarly small exothermal peak (Texo) around 130°C, just prior to the melting point, corresponding to the disorder-to-order (a’-to- a) phase transition, while the sample annealed at temperature (Ta: 90-110°C) shows a double melting behavior considered as the a'- a phase transition. At Ta>110°C, the a′ -form of PLA was found to transform into the a one during the annealing process. The a’- a phase transition around 100°C (Ta: 90-110°C), determined from the two melting peaks (Tm1 and Tm2) as function of Ta at different times ta, shows a good correlation with the substantial increase in the crystallinity rate (Xc) with a maximum of 32% at Ta=120°C. Towards low temperatures, the glass modulus Eg reported by DMA thermograms, shows an important increase (~30 000 MPa) at Ta=80°C for ta=3 h, due to the nucleation density extremely high in low PLA materials crystallization. After a sharp drop to 3 600 MPa at Ta=110°C, a marked improvement of Eg (15 900 MPa) is observed around Ta=120°C for all samples, regardless of time ta, temperature region where PLA is usually molded in the industrial melt processing. This interesting effect (improvement of Eg in range Ta=100-120°C) can be correlated with the grow of crystallinity in the same domain of Ta, and the a’- a phase transition Ta (Ta: 90-110 °C) determinate by the double Tm melting DSC peak, which is confirmed by the increase of Tg for Ta=90-110°C.
Predictors of Traditional Herbal Medicine Use Among Cancer Patients in Morocco
Authors: karima selmaoui , ouzennou nadia , mohamed aboufaras 
Published: June 2022

Abstract
Background
Although some Moroccan studies have shown a high frequency of use of traditional and complementary medicines (T&CM). No survey has investigated the predictive factors of the use of traditional herbal medicine.
Methods
At the regional oncology center of Beni Mellal, we conducted a descriptive and analytical cross-sectional study with 530 adult cancer patients chosen by quota sampling. A 54-item questionnaire was used to perform the face-to-face survey. The theory of planned behavior (TPB )and a CAM healthcare model were used to create this instrument. Using SPSS software, we performed bivariate and multivariate statistical analysis as well as logistic regression.
Results
The prevalence of traditional herbal medicine use was 36.6%. Several variables of the conceptual model were associated with the use of herbal medicine (gender, attitude and belief towards T&CM, financial resources, clinical characteristics of patients)(p < 0.05). Predictors of traditional herbal medicine use were female gender (OR = 4.687; p < 0.000), social impact of cancer(OR = 2.314; p < 0.05), emotional impact of cancer (OR = 2.314; p < 0. 05), Expected benefits of TM/CAM use(OR = 3.453; p < 0.000), perceived scientific barriers (OR = 0.580; p < 0.000), perceived socioeconomic barriers(OR = 0.657; p < 0.005), use and social norms of relatives(OR = 3.238; p < 0).
Conclusion
Because of the high prevalence of herbal medicine, health care providers should focus on specialized and multidisciplinary therapeutic education that focuses on the psychosocial factors and representations that underpin this use.
Analysis of rheumatic heart disease mortality in the Chinese population: A JoinPoint and age-period-cohort study
Authors: Cui Jiameng , Guo Xinru , Yuan Xin , Wu Hao , Yu Ge , Li Biao , Kou Changgui 
Published: June 2022

Abstract
Background: The aim of this study was to analyze rheumatic heart disease (RHD) mortality trends in China’s urban and rural areas and to determine the roles of age, period, and cohort effects. Methods: Based on mortality data extracted from the Chinese Health Statistics Yearbook, we calculated the crude mortality rate of RHD in China. Age-adjusted rates were computed by the direct method using the 2020 census as the standard population. The annual percentage change (APC) and average annual percentage change (AAPC) were determined by the JoinPoint regression model. The age-period-cohort model and the intrinsic estimator (IE) algorithm were used to estimate the effects of age, period, and cohort. Results: From 2006 to 2020, the general trend in RHD standardized mortality declined. The RHD mortality rate was higher in rural than in urban areas and among females than males. JoinPoint regression showed that the elderly (over 60 years old) were at high risk for RHD deaths in China. The age effect increased with age, and the cohort effect showed an overall declining trend as chronology grew, but the period effect was not significant. Conclusions: China has achieved great success in RHD, but RHD mortality may increase with age. We should focus on publicity and education about RHD among the elderly. Compared with the period effect, age and cohort effects dominated the risk of RHD deaths.
A large effect QTL introgressed from ricebean imparts resistance to Mungbean yellow mosaic India virus in blackgram (Vigna mungo (L.) Hepper)
Authors: Dhaliwal Sandeep Kaur , Gill Ranjit Kaur , Sharma Abhishek , Kaur Amandeep , Bhatia Dharminder , Kaur Satinder 
Published: June 2022

Abstract
Until recently, precise location of genes and marker assisted selection was long thought in legumes such as blackgram due to lack of dense molecular maps. However, advances in next generation sequencing based high throughput genotyping technologies such as QTL-seq have revolutionized trait mapping in marker-orphan crops. Using QTL-seq approach, we have identified a large effect QTL for resistance to Mungbean yellow mosaic India virus (MYMIV) in blackgram variety Mash114. MYMIV is devastating disease responsible for huge yield losses in blackgram, greengram and other legumes. Mash114, a blackgram variety developed by Punjab Agricultural University, India showed consistent and high level of resistance to MYMIV since last nine years. Whole genome re-sequencing of MYMIV resistant and susceptible bulks derived from RILs of cross KUG253 X Mash114 identified a large effect QTL (qMYMIV6.1.1) spanning 3.4 Mbp on chromosome 6 explaining 70 per cent of total phenotypic variation. This region was further identified as an inter-specific introgression from ricebean. The annotation of the introgressed segment suggested presence of clusters of disease resistance domains of which nine candidate genes were found to have role in virus resistance. Linkage mapping using KASP markers developed from these nine candidate genes identified the 500 kb genomic region equaling 1.9 cM on genetic map linked with MYMIV. The three KASP markers closely associated with MYMIV originated from serine threonine kinase, UBE2D2 and BAK1/ BRI1-ASSOCIATED RECEPTOR KINASE genes. These KASPs can be used for marker assisted transfer of introgressed segment into suitable backgrounds of Vigna species.
Development and Analysis of Human Hair Fiber and Chicken Feather Reinforced Composite
Authors: Worku Tesfaye , Nachippian Sukumar , no no 
Published: June 2022

Abstract
In the current year, composites have been concerned with considerable importance as a potential operational material. Many works have been carried out to enhance the mechanical properties of composites. Chicken feather, human hair and hairs of other birds and animals are commonly described as a waste product. Currently, available disposal methods such as burying and burning of these waste by-products are contributing to environmental pollution. In this research work composite was developed using human hair & chicken feather fiber and analysis the mechanical and physical property of the developed composite sample. Four different composition ratio composite samples were fabricated and then physical and mechanical properties were tested according to standards. Both flexural and compressional strength increase for the first two composite samples, then after it shows a gradual decrease when we have increased the fiber content and decreased resin and sample show that the amount of water absorption in percentage increases when the fiber content increases, and the matrix material (polyester resin) decrease. This research study indicates that using human hair and chicken feather fibers as reinforcement in a polymer matrix could successfully develop a composite material in terms of high strength and rigidity for lightweight house ceiling board material.
Combination of Pioglitazone, a PPARγ Agonist, and Synthetic Surfactant B-YL Prevents Hyperoxia-induced Lung Injury in Adult Mice
Authors: Kurihara Chie , Sakurai Reiko , Chuang Tsai-Der , Waring Alan J. , Walther Frans J. , Rehan Virender K. 
Published: June 2022

Abstract
Introduction: Acute lung injury and acute respiratory distress syndrome are characterized by acute alveolar injury, disrupted epithelial-mesenchymal signaling, oxidative stress, and surfactant dysfunction, yet currently, there is no effective treatment. We previously reported that a combination of aerosolized pioglitazone (PGZ) and synthetic lung surfactant B-YL peptide as surfactant protein B mimic prevents hyperoxia-induced neonatal rat lung injury, but this has not been tested in adult lung injury. Method: We characterize effects of hyperoxia on 1) perturbations in Wingless/Int (Wnt) and Transforming Growth Factor (TGF)-β signaling pathways, which are critical mediators of hyperoxia-induced lung injury, 2) aberrations of lung homeostasis and injury repair following 24 or 72-hour exposure of adult mice lung explants to hyperoxia, and 3) whether these hyperoxia-induced aberrations can be blocked by concomitant treatment with PGZ and B-YL combination. Results: Our study reveals that hyperoxia exposure of adult mouse lung explants causes activation of Wnt (upregulation of key Wnt signaling intermediates β-catenin and LEF-1) and TGF-β (upregulation of key TGF-β signaling intermediates TGF-β type I receptor (ALK5) and SMAD 3) signaling pathways accompanied by an upregulation of myogenic proteins (calponin and fibronectin) and inflammatory cytokines (IL-6, MCP-1, IL-1β, and TNFα), and alterations in key endothelial (VEGF-A and its receptor FLT-1 and PECAM-1) markers. All of these changes were largely prevented by PGZ+B-YL combination. Conclusions: The effectiveness of the PGZ+B-YL combination in blocking hyperoxia-induced adult mice lung injury ex-vivo sets the stage to test this promising therapeutic approach for adult lung injury in vivo.
Effect of silica fume on the behavior of lightweight RC beams made from crushed bricks
Authors: Ali Yahia M. S. , abdelaleem Tarek 
Published: June 2022

Abstract
Crushed Over-Burnt Clay Bricks (COBB) is a promising alternative to the natural gravel aggregate in Lightweight Concrete production because of its high strength-to-weight ratio. In addition, COBCB is considered a green aggregate by solving the problem of disposing of this solid waste. in this paper, a total of fifteen Reinforced Concrete beams were constructed and tested up to failure. The experimental program was classified to five groups, the first group was casted with Normalweight Concrete (NWC) as control, the remaining four groups were casted with LWC. The test parameters were concrete type, reinforcement ratio and silica fume (SF) content. The behavior of beams was evaluated in terms of crack patterns, failure mode, ultimate deflection, and ductility. Based on the experimental results, the resulting concrete showed that it satisfies the requirements of LWC in terms of unit weight and strength. In addition, increasing the reinforcement ratio and silica fume content increased overall beam performance. The results revealed that measurable enhancements to the majority of the performance characteristics of LWC beams by adding SF. Thus, using COBCB as a coarse aggregate has successfully been used to produce good quality lightweight concrete. Both ACI 318-14 and CSA-A23.3-14 give acceptable for predicting cracking moment, ultimate capacity and and mid-span deflection.
Habitat preferences, dispersal and demography of two saproxylic longhorn beetles (Cerambycidae: Rosalia alpina, Morimus asper funereus): A case study from the Julian Alps, Slovenia
Authors: JUGOVIC Jure , POGORELEC Nika , LUŽNIK Martina 
Published: June 2022

Abstract
Saproxylic beetles are a diverse and predominant functional group that depend on dead or dying wood. We studied a population of two saproxylic longhorn beetles Rosalia alpina and Morimus asper funereus in a system of 12 potentially suitable habitat patches in a forest reserve in Triglav National Park, Slovenia. For each species we determined demographic parameters, dispersal, and microhabitat preference. We marked 68 individuals of M. a. funereus, 27 individuals of R. alpina. The best-fitting MARK model for M. a. funereus suggested the presence of two groups with different capture probabilities, probably a larger group of non-territorial males and females with lower capture probability, and a smaller group (1–13% of the population) of territorial males with higher capture probability. The total population size was estimated to be about 208 individuals (95% confidence interval 118–462) of M. a. funereus. For R. alpina, estimation of population size was not possible due to scarce recaptures. We detected several short-distance movements (maximum 34 m) for M. a. funereus and rare but longer movements for R. alpina (maximum 457 m). A preference for dead (preferred by R. alpina) or decaying (preferred by M. a. funereus) beech trees (Fagus sylvatica) with large diameters was observed for both species. Implications for insect conservation: Forest reserves with negligible human impact and an abundance of old, intact trees are important for the successful life cycle of both species studied, even more so when both competing species occur together.