bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of cardiovascular disease risk factors knowledge level, Framingham score, and cardiac markers in a healthy population
Authors: TOPUZ Ayşe Nur , BOZDEMİR Nafiz 
Published: September 2022

Purpose: The iam of this study was to assess the cardiovascular knowledge level of an educated and healthy population and determine how much they transferred it to daily life. In the current study, we first determined Cardiovascular Disease (CVD) Risk Factors Knowledge Level and Framingham score and investigated their relationship between pulse wave velocity (PWV) and laboratory parameters of healthy personal working for Cukurova University.
Materials and Methods: The study was conducted via 192 participants who were selected from the study sample among healthy personnel working for Cukurova University. All participants' knowledge level was determined with the Cardiovascular Disease Risk Factors Knowledge Level (CARRF-KL) scale and the 10-year risk for development of CVD determined by the Framingham risk score. PWV was also determined non-invasively by using an arteriography device. Blood samples were collected from all participants.
Results: The mean age of all participants was 45.3 ± 8.0 years (53.6% woman). The mean CARRF-KL score of the participants was found as 20.4 ± 4.0 and the mean Framingham score was found 6.9±5.6. The average PWV was found 7.9±1.5m/sn. In correlation analyses, PWV was well correlated with both the mean CARRF-KL score and Framingham score. Participants who had the highest CARRF-KL score had also the highest Framingham score and PWV .
Conclusion: Despite the high level of education and knowledge, it is seen that this knowledge is not reflected in daily lives in terms of CVD risk factors. Further studies are needed whether there is a threshold level of CVD knowledge that must be attained for knowledge to influence behavior and risk factor levels. For effective prevention, knowledge should be supported by behavioral counseling interventions.
Effect of distal locking type on radiological results of proximal femoral nails used in the surgical treatment of hip fractures
Authors: DAVUT Serkan 
Published: September 2022

Purpose: The aim of our study is to obtain data that will shed light on the effect of the distal locking type of proximal femoral nails (PFN) on fracture healing, causes of general complications, especially those in the distal of the nails, and reduction of possible complication rates.
Materials and Methods: Patients who underwent surgery with the diagnosis of trochanteric hip fracture between 01.01.2015 and 01.01.2020 and completed the second year follow-up time were examined from the medical records. Patients were grouped first according to AO/OTA sub-types (Three groups as AO A1, A2 and A3), then grouped according to distal locking type (Two groups as group 1: dynamic, group 2: static distal locking with 2 screws). The fracture type, healing status, fracture healing time, complication rates and reoperation because of complication development data were evaluated.
Results: 339 patients enrolled in the study [189 women, 150 men, mean age: 76.24 (60-102) years]. The overall complication rate was 15.6%. AO A3 type fractures had long fracture healing times in each distal locking group compared to the other fracture sub-types. AO A3 type fractures had more frequent complication rates than the other subtype groups. AO A3 type fractures in group 2 had higher overall complication rates than in group 1. There was a significant correlation between group 1 and lag screw cut-out complication occurrence in females and between group 2 and pseudoarthrosis occurrence in males. In addition, there was a statistically significant relationship between the AO fracture sub-type and total rate of complication occurrence, AO A2 fracture type and lag screw cut-out complication occurrence and AO A3 fracture type and pseudoarthrosis complication occurrence.
Conclusion: Patients with AO/OTA 31 A3 type fractures with static distal locking have a longer fracture healing time and a higher complication rate compared to dynamic locking. However, dynamic or static distal locking is not associated with other implant-related complications, especially those in the distal to the tip of PFN’s.
Relationship between childhood trauma, dyadic adjustment, and sexual functions in patients with bipolar disorder
Authors: KULACAOĞLU Filiz , İZCİ Filiz , YİLDİRİM Yusuf Ezel , DIŞPINAR Nazmiye İlayda , CESUR Merve Sinem 
Published: September 2022

Purpose: This study aimed to investigate the dyadic adjustment and sexual functions in patients with bipolar disorder (BD) during the remission period, and examine the effect of a history of childhood trauma on these.
Materials and Methods: This cross-sectional study is consisted of 80 (46 female, 34 male) patients with bipolar disorder-1 and 40 (25 female, 15 male) healthy controls. The Dyadic Adjustment Scale (DAS), Childhood Trauma Questionnaire (CTQ-28), Arizona Sexual Questionnaire (ASEX) were administered to the participants.
Results: The patient group showed significantly higher trauma scores in all subscales and total scores of the CTQ-28, and lower scores in the subscales and total score of DAS compared to the control group. 82.5% of bipolar patients and 57.5% of healthy controls were found to have sexual dysfunction (SED). According to the results of linear regression and multiple regression analyses, age and DAS-total score predicted SED, and male gender, absence of SED and CTQ-total score predicted DAS score.
Conclusion: Patients with BD have more dyadic problems, sexual dysfunction, and trauma history than healthy controls. Sexual function and dyadic adjustment affect each other in two ways and a history of childhood trauma has a negative effect on both sexual function and dyadic adjustment.
Occupational Stress and Resilience among Nurses in the Time of Covid-19 Pandemic
Authors: Kargar-Shouroki Fatemeh , Abrchi Arghavan , Jambarsang Sara , Mortazavi Morteza , Shafiei Rachi Mohammad 
Published: September 2022

Background: During Covid-19 pandemic, nurses are one of the most important job groups who experience high levels of stress. This study aims to compare occupational stress and resilience among nurses working in COVID-19 and non-COVID-19 wards.
Methods: In this cross-sectional study, 130 nurses participated. To determine the occupational stress and resilience, Osipow Occupational Stress Inventory (OSI) questionnaire and Connor-Davidson Resilience Scale (CD-RISC) were used as collecting data tools, respectively.
Results: The total stress score (176.63±15.86 versus 164.47±13.21, p= 0.02) was significantly higher, while the mean score of resilience was significantly lower (65.61±2.75 versus 78.76±2.61, p<0.001) in nurses working in COVID-19 wards, compared with the nurses in other wards. After adjusting for confounders, there were statistically significant associations between occupational stress and control subscale of resilience and between resilience and hospital wards (COVID-19 and non-COVID-19 wards).
Conclusion: The present study's findings indicated that nurses working in COVID-19 wards have higher stress and lower resilience than nurses in other wards.
Application of Hazard and Operability Analysis (HAZOP) Method for Risk Analysis in CGS Station
Authors: Hokmabadi Rajabali , Karimi Ali 
Published: September 2022

Background: The hazard and operability study (HAZOP) method is a risk assessment method based on engineering systems used for qualitative analysis or quantitative evaluation. It is mainly used to discover potential hazards and operational difficulties in the design and qualitative stages of chemical systems. The study aims to apply the HAZOP method in process and safety operations at gas depressurization station.
Methods: This descriptive study was performed at CGS station. The station was divided into four principal nodes including: filter, heater, regulator, and odorize part. Required information for HAZOP worksheets were gathered by operational procedures, daily reports and interviews with engineers and operators working at the station. To determine the severity of consequences and probability of occurrence of scenarios that were predicted based on the risk matrix, the amount of risk was specified and the necessary suggestions were made in this regard.
Results: According to this study, the operational indicators in the pressure reducing station process included pressure, flow, level and temperature. 22 main deviations and 50 causes of failures were identified. 5 deviations (23%) were in the low risk range (green area) and 17 (77%) were in the medium risk range (yellow area).
Conclusions: Causes and effects of deviations in operational parameters at four nodes in gas depressurization station were identified by HAZOP. Preventive actions were emphasized, such as consistent inspection of pipelines, preventive and timely maintenance and preparing a well-scheduled plan for inspecting the equipment in terms of corrosion, inspection, and design revision.
Learning Strategies and Technologies Applied by High Proficiency University Students for English as a General Subject
Authors: Sufiyandi Sufiyandi , Fadhli Muhammad , Kurniawan Ildi 
Published: September 2022

Learning strategy is an important factor in the success of achieving communicative language skills. Besides the awareness of using various strategies, applying technology in the language learning activity also becomes crucial for learners to succeed. However, learning strategies and the use of technologies by students of English Subjects at colleges and universities have not been widely found in the literature. For this reason, the research is aimed at finding out the application of strategies and technologies used by high proficiency students. The research is designed by combining both qualitative and quantitative research as the so-called Mixed Method. The participants involved were 33 high proficiency students in English subjects. They were taken based on the tests from 169 students spreading across four faculties at Universitas Bengkulu – Sumatera, Indonesia. After providing the test to determine the high proficiency student, the questionnaires were administered to collect the data related to the strategies and technologies applied by the students. Eventually, an interview was also undertaken to gain the qualitative data. Based on the questionnaire data, it was found that the students applied all learning strategies, namely: memory, cognitive, metacognitive, compensation, affective, and social strategies. Of the six strategies, metacognitive was the strategy mostly used with a mean score of 3.771 and followed by cognitive strategy with 3.643 points. Meanwhile, the least used ones were compensation and social, which have a value of 3.419 and 3.460, respectively. In addition, based on the interview, the use of technology as a learning strategy was also concluded. The high proficiency students applied various technologies such as mobile phones, various Internet Websites, and language applications to practice English. Of these various technologies, mobile phones were the most dominant.
Teaching Speaking through Story Telling: The Case of a Junior High School
Authors: Yelia Yelia , Wahyuni Vera , Rachmawati Rachmawati , Efriza Dony 
Published: September 2022

This collaborative classroom action research described the use of storytelling in teaching English speaking. The subjects of the research were 13 junior high school students at SMP Laboratorium STKIP Jambi, Indonesia. The qualitative data consisted of field notes, students’ diaries, photographs, and videos of teaching and learning process collected through observations and analyzed descriptively. The quantitative data were the students' scores in their English speaking performance generated through speaking tests and analyzed by using Microsoft Excel. The findings showed that the use of storytelling in teaching speaking could attract students’ attention to the lesson and encourage them to speak English. Pronouncing words, constructing sentences, and retelling the story could enhance students’ speaking performance. The students’ mean scores in their speaking performance tests got a significant improvement from cycle to cycle.
The Markup on Orthopaedic Services: An Analysis of 2014-2019 Medicare Data and the Potential for Surprise Billing
Authors: Burkhart Robert J. , Acuña Alexander J. , Zhu Kevin Y. , Kamath Atul F. 
Published: September 2022

Background:Markups on charges for medical services have the potential to result in “surprise billing,” especially for out-of-network and uninsured patients. Although previously analyzed in other surgical subspecialties, the distribution and level of cost-to-charge ratios (CCRs) for orthopaedic services have yet to be studied. Therefore, our analysis sought to evaluate the CCRs for orthopaedic surgery services provided to Medicare beneficiaries throughout the United States.Methods:Orthopaedic services provided to Medicare Part B beneficiaries between 2014 and 2019 were identified in the Physician & Other Practitioners database of the Centers for Medicare & Medicaid Services (CMS). CCRs, representing the ratio between the actual payment provided by CMS and the charge submitted by the provider, were calculated for each service. Descriptive statistics were calculated for CCRs at the national, state, and service-code levels. The coefficient of variation (CoV) was utilized to evaluate variability in CCRs across services and states. Additionally, Mann-Kendall tests were performed to evaluate trends in CCRs for included services over the time frame.Results:Our analysis included an annual mean of 47,247,928 services provided by a mean of 23,185 orthopaedic surgeons over the study period. In the non-facility setting, there was a decrease in median CCRs for orthopaedic surgery services (0.29 to 0.27; p = 0.024). No changes were demonstrated for facility-based services. Service codes related to trigger finger procedures (0.18 to 0.17; p = 0.004), physical therapy (0.40 to 0.36; p = 0.035), and new patient visits (0.52 to 0.46; p = 0.035) demonstrated significant decreases in median CCRs. Only shoulder arthroscopy demonstrated a significant increase in median CCR (0.09 to 0.10; p = 0.003). High dispersion in CCRs was demonstrated for 16 (80%) of the 20 evaluated services. Wide variations in CCRs were demonstrated across individual states (median, 0.57; interquartile range width, 0.53).Conclusions:Our analysis demonstrated low and variable CCRs for commonly performed orthopaedic services in the U.S. These findings serve to inform and help improve related price transparency policies. Additionally, our analysis encourages increased efforts at preventing these low CCRs from limiting care in vulnerable populations.
Pseudo-classification of natural elements and atomic total energy prediction
Authors: Belahcene Brahim 
Published: September 2022

Abstract

Technological development requires the search for new materials with specific properties. Moreover, the forecasting of physical and chemical compound formation and proprieties can be based on Datamining methods. In this paper, one of the unsupervised methods of Datamining is used, like Principal Component Analysis (PCA). The first goal is to make pseudo-classification of natural and synthetic elements of the periodic table based on all physicochemical and energy available properties. Likewise, the second goal is to test the effectiveness of this statistical method to estimate correlations and appreciate the relationships between the variables and properties. A pseudo-classification of periodic elements is a new way of seeing Mendeleev's table. At the end of this work, a predictive polynomial has been presented that can allow the scientific community to make atomic total energy predictions for each natural periodic element, from Z=2 to Z=103.
Estimates of Cardiovascular Diseases Burden Attributable to High Sodium Intake from 1990 to 2019: A Systematic Analysis of Data from the Global Burden of Disease Study
Authors: Wang Keke , Jin Yaqiong , Wang Mengxiao , Liu Jing , Bu Xiang , Mu Jianjun , Lu Jingchao 
Published: September 2022

Abstract

Background
Sodium intake shows a positive correlation with blood pressure, resulting in an increased risk for cardiovascular diseases (CVD). Salt reduction is a key step toward the WHO's goal of 25% reduction in mortality from noncommunicable diseases (NCDs) by 2025. This study aims to assess the current condition and temporal changes of the global CVD burden due to high sodium intake.
Methods
We extracted data from the Global Burden of Disease (GBD) study 2019. The numbers and age-standardized rates of mortality and disability-adjusted life-years (DALYs), stratified by location, sex, and socio-demographic Index (SDI), were used to assess the high sodium intake attributable CVD burden from 1990 to 2019. Stepwise multiple linear regression analysis was performed to evaluate the relationship between the DALYs rates and related factors.
Results
Globally, in 2019, the deaths and DALYs of high sodium-related CVD were 1.72 million and 40.54 million, respectively, increasing by 41.08% and 33.06% from 1990. Meanwhile, the corresponding mortality and DALYs rates dropped by 35.1% and 35.2% respectively. The high-middle and middle SDI quintiles bore almost two-thirds of the CVD burden caused by high sodium, while the high SDI quintile had the lowest DALYs rate with the greatest annual decline. Males and the elderly had a higher risk suffering CVD from high dietary sodium. And the leading causes of high sodium intake attributable CVD burden were ischemic heart disease, stroke, and hypertensive heart disease. Universal health coverage (UHC) was significantly associated with the DALYs rates after adjustment.
Conclusions
From 1990 to 2019, the global CVD burden attributable to high sodium intake has declined with spatiotemporal and sexual heterogeneity. However, it remains a major public health challenge because of the increasing absolute numbers in DALYs and mortality. Improving universal health coverage may serve as an effective strategy to reduce the high sodium-related CVD burden.
Intraocular Pressure Variations in Postural Changes: Comparison Between Overweight and Normal BMI Controls
Authors: De Bernardo Maddalena , PILONE VINCENZO , PAOLA ILENIA DI , Cione Ferdinando , CEMBALO GIOVANNI , CALABRESE PIETRO , Rosa Nicola 
Published: September 2022

Abstract
Background:to compare intraocular pressure (IOP) changes (ΔIOP) between obese patients and normal weight controls in relation to different positions: standing, sitting and supine.
Subjects and Methods: Patients candidates for bariatric surgery and normal weight controls. IOP was measured both in patients and controls with Tono-Pen AVIA in different positions. The utilized sequence was: after 5 minutes (5’) in standing position, sitting, supine, 5’supine, and immediately after standing. ΔIOP obtained by supine positions and all other positions were therefore evaluated.
Results: Ninenty-two eyes of 46 obese patients (14 males) with an age between 18 and 59 years (mean 38.07±11.51 years) and BMI between 31.84 and 60.65 (mean 41.84±7.05) were evaluated. Forty-eight eyes of 24 normal weight controls (5 males) aged between 23 and 55 (mean 35.21±11.96 years) and BMI between 18.20 and 26.79 (mean 21.04±2.36) were also recruited. In obese patients there were statistically significant differences between IOP in supine position and supine positions 5’ with all other IOP measurements (all P<0.05). There were statistically significant differences between ΔIOP in both supine positions and prolonged standing positions obtained by patients and controls. (P<0.05).
Conclusions: In obese patients there is a statistically significant increase in IOP in the supine positions that is significantly greater than normal weight population. BMI is weakly correlated with IOP and ΔIOP in postural changes.
Single and multiple quality characteristics optimization, expanded to the machinability assessment at the optimal cutting combinations across Taguchi OA, GRA and BBD: an overall view
Authors: Tebassi Hamid , Yallese Mohamed Athmane , Belhadi Salim 
Published: September 2022

Abstract
The Inconel 718 is among the most used alloy in several industrial fields, so it was necessary to develop appropriate modeling, optimization, and prediction methods during the turning of this material; in terms of minimum experiments for giving good competitiveness to final products. In this research paper, turning experiments have been performed under a dry environment with different conditions of cutting speed, feed rate, and depth of cut, using Taguchi design along with Grey Relational Analysis and Box-Behnken design when turning of Inconel 718. Initially, design evaluation is achieved based on their fraction of design space graphs. Then, optimization single and multi-objective are satisfied, and a general comparison of short and long-term is achieved apropos optimal cutting regimes. Mono-objective optimization through Taguchi orthogonal array shows the carelessness of responses outside the optimization object. On the other hand, multi-objective optimization relating to Taguchi-Grey produces better results regarding its reduced number of experiments. The Box-Behnken design implements a good fit for multi-attribute optimization. Nevertheless, its higher number of experiments must be considered regarding their costs. Moreover, a comparative study for the short and long term can demonstrate a suitable and accurate approach regarding its optimal cutting combination. The Grey-Taguchi approach displays good results in terms of multi-attribute optimization against the Box-Behnken design. This judgment is based on the balancing of the obtained accuracy regarding the smallest design. However, the tool wear long-term test is integrated as a criterion of better machinability relating to the optimal cutting combinations.
Anemonin attenuates hydrogen peroxide-induced oxidative stress, inflammation and extracellular matrix degradation in nucleus pulposus cells by regulating NOX4/NF-κB signaling pathway
Authors: Ma Zhijia , Yu Pengfei , Li Xiaochun , Dai Feng , Jiang Hong , Liu Jintao 
Published: September 2022

Abstract
Backgroud:
Excessive oxidative stress plays a critical role in the progression of various diseases, including intervertebral disc degeneration (IVDD). Recent studies have found that anemonin (ANE) possesses antioxidant and anti-inflammatory effects. However, the role of ANE in IVDD is still unclear. Therefore, this study investigated the effect and mechanism of ANE on H2O2 induced degeneration of nucleus pulposus cells (NPCs).
Methods
NPCs were pretreated with ANE, and then treated with H2O2. NOX4 was upregulated by transfection of pcDNA-NOX4 into NPCs. Cytotoxicity was detected by MTT, oxidative stress related indicators and inflammatory factors were measured by ELISA, mRNA expression was assessed by RT-PCR, and protein expression was tested by western blot.
Results
ANE attenuated H2O2-induced inhibition of NPCs activity. H2O2 enhanced oxidative stress, namely, increased ROS and MDA levels and decreased SOD level. However, these were suppressed and pretreated by ANE. ANE treatment repressed the expression of inflammatory factors (IL-6, IL-1β and TNF-α) in H2O2-induced NPCs. ANE treatment also prevented the degradation of extracellular matrix induced by H2O2, showing the downregulation of MMP-3, 13 and ADAMTS-4, 5 and the upregulation of collagen II. NOX4 is a key factor regulating oxidative stress. Our study confirmed that ANE could restrained NOX4 and p-NF-κB. In addition, overexpression of NOX4 counteracted the anti-oxidant and anti-inflammatory activities of ANE in H2O2-induced NPCs, and the inhibition of the degradation of extracellular matrix induced by ANE was also reversed by overexpression of NOX4.
Conclusion
ANE repressed oxidative stress, inflammation and extracellular matrix degradation in H2O2-induced NPCs by inhibiting NOX4/NF-κB pathway. Our study indicated that ANE might be a candidate drug for the treatment of IVDD.