bluuebunny/crossref_metadata_2025_split huggingface dataset:
Granulation multi-label decision tables and three-level granulation attribute reductions of multi-label decision tables
Authors: Wang Zhaohao , Zhang Xiaoping 
Published: February 2022

Abstract
Multi-label data is an important data type in machine learning. The rough set theory has been successfully used to deal with various data. However, the application of rough set theory to multi-label data is still not perfect. In this paper, we investigate the attribute reduction of multi-label data. First, in order to explore the attribute reduction of a multilabel decision table, this paper constructs the granulation multi-label decision table of a multi-label decision table. Moreover, we divide the granulation multi-label decision function in the granulation multi-label decision table to three levels, that is, macroscopic level, mesoscopic level and microscopic level. Second, we give some new characterizations of the complementary decision reduction of a multi-label decision table by means of the three-level granulation multilabel decision functions. Third, we define the concept of a granulation attribute reduction of a multi-label decision table, and establish three-level granulation attribute reductions, that is, the macroscopic-level, the mesoscopic-level and the microscopic-level granulation attribute reduction. Furthermore, we show that a complementary decision reduction of a multi-label decision table can be seen as a macroscopic-level granulation attribute reduction and thus it can be interpreted as a positive region reduction. Finally, by several comparative analysis, the reasonability, feasibility and effectiveness of the granulation attribute reduction are demonstrated.
A Study Protocol for Randomized Trials on Visual ERP for multiclass discrimination in CAAD applications
Authors: Cutellic Pierre , Qureshi Nauman Khalid 
Published: February 2022

Abstract
Background: A great part of brain-computer interfaces (BCI’s) research has so far, been focusing on interactions using exogenous responses under selective attention with synchronous and reactive methods for clear relation with controlled stimuli and the widespread applicability of the methods. Over the two past decades, event-related potentials (ERP’s) have become more and more investigated for a broader community of researchers due to the relatively little amount of training necessary for a system to perform and their detection across diverse modalities of acquisition to correlate with the sensory discrimination of dedicated stimuli. The proposed study aims to observe the detection of ERP’s components and correlated neuralphenomena under the visual presentation of complex stimuli and devise processing methods that would generalize their classification for applications in computer-aided architectural design (CAAD), where visual complexity becomes an intrinsic feature of the tasks.Methods: Its objective is exploratory and twofold: evaluating data processing and stimulus presentation methods, as well as the evolution of similar responses in repeated measures intra- and inter-subjects in non-clinical states. The study is divided into 4 phases of offline-online experiments across its timeline. Offline experiments are used to study and validate base methods, and online experiments are used to validate their modifications for application usage. Each of these experiments are framed by cross-sectional and longitudinal sub-studies. The chosen neural phenomena and study, as well as the presentation paradigm, precondition the trial design with repeated measures for averaging temporal waveforms within an exploratory framework. An expected total of at least 200 participants will be recruited over the course of the study. The aim is to recruit for a distribution of age, gender and participants that are involved in studies or practices of architecture, visual arts or related to maximize statistical significance regarding the targeted population segment.Discussion: This study aims to investigate the cardinality of discriminative neural patterns correlated with the presentation of complex visual stimuli by detecting subcomponents of these neural phenomena using the designed system on short and prolonged periods of time and involving participants from architecture, visual arts or related fields. Subsequent results will bring to further discussion the role of visual experience in such system and the range it might address in the population segment.Trial Status: The first phase of the study has been submitted for non-clinical trials and approved by ETH Z¨urich Ethics Commission on the 02nd July 2021 and given the registration ID: EK 2021-N-106. The first trial has been approved on August 1st 2021
A Pregnant Woman With Severe Pulmonary Hypertension Due to an Atrial Septal Defect That Was Triggered by Pregnancy
Authors: Mishima Sakurako , Mitsui Takashi , Akagi Satoshi , Mitoma Tomohiro , Ohira Akiko , Tani Kazumasa , Maki Jota , Kirino Satoe , Eto Eriko , Hayata Kei , Ito Hiroshi , Masuyama Hisashi 
Published: February 2022

Abstract
Background: Pregnancy is contraindicated in patients with pulmonary hypertension (PH). Here, we report a case of a pregnant woman with severe PH due to an atrial septal defect (ASD) that was triggered by pregnancy.Case Presentation: A 27-year-old woman with gravida 3 and para 2 presented with dyspnea in the fifth or sixth month of pregnancy, which gradually worsened. At 35+4 weeks of gestation, echocardiography revealed a transtricuspid pressure gradient (TRPG) of 120 mmHg, a sign of right heart failure; thus, she was diagnosed with severe PH. Because it was unsafe to continue pregnancy, an elective cesarean section was performed at 35+6 weeks under general anesthesia. A female infant weighing 1880 g was delivered; her Apgar scores were 8 and 9 after 1 and 5 minutes, respectively. Intraoperative transesophageal echocardiography revealed an ASD in the mother’s heart, a possible cause of PH. After the delivery, the mother was treated with an epoprostenol infusion via Hickman line, which was continued, along with home oxygen therapy, after she was discharged from the hospital. Nine months later, she underwent transcatheter closure for the ASD and her PH resolved. Conclusion: In pregnant patients with PH, the baby should be delivered at the appropriate time to relieve the pressure on the patient’s hemodynamics. This should be followed by strict circulation management including the requisite medical and surgical interventions to restore cardiac function.
Prediction of ABO Hemolytic Disease of the Newborn Using Prenatal Quantification of Maternal Vascular Endothelial Cadherin and anti-A/anti-B IgG Titer in China
Authors: Jiang Dandan , Ding Jiane , Shao Shuling , Dong Xiumei , Li Shanshan , Liu Peng 
Published: February 2022

Abstract
Objective To study the value of maternal vascular endothelial cadherin (VE-cadherin) level and anti-A/B IgG titer in the prenatal diagnosis of ABO hemolytic disease. Methods We conducted a case-control study of blood group O Rh(D) positive mothers according to the occurrence of ABO-HDFN in newborns. Then the level of maternal VE-cadherin and anti-A /B IgG titer of the two groups were compared and analyzed, and their correlation with total bilirubin in children, and their value for the prenatal diagnosis of ABO-HDFN was analyzed.Results The VE-cadherin level and anti-A/B IgG titer of pregnant women in the ABO-HDFN group were higher than those of the control group (P<0.001). There was a positive correlation between VE-cadherin level and total bilirubin (r=0.3520, P<0.05) in the ABO-HDFN group, but no significant correlation between IgG titer and TBIL (r=0.1289, P=0.4605). The AUC of the VE-cadherin level was 0.762, the sensitivity and the specificity was 80.95%, 63.16%; the AUC, sensitivity and specificity of IgG titer were 0.862, 88.10% and 71.05%, respectively. The AUC, sensitivity and specificity of the combined diagnosis were 0.915, 92.86% and 84.21%, respectively. Conclusion The level of maternal VE-cadherin and anti-A/B IgG titer have important reference value for the prenatal diagnosis of ABO-HDFN, and they have good joint diagnostic efficacy.
Efficient wastewater treatment by utilizing biomass derived adsorbent: A comprehensive study to prove its commercial viability
Authors: Khan Rana Zahir , Khurram Muhammed Shahzad , Rafiq Sikander , Inayat Abrar , Hussain Arif , Bokhari Awais , Aslam Muhammed , Jamil Farrukh 
Published: February 2022

Abstract
This research projected the productive use of chickpea for wastewater treatment. Iron (Fe) based nanoparticles were deposited on chickpea husk (agro-based) and used for the removal of phenolic compounds from wastewater. The material was characterized using XRD, FTIR, magnetic effect test and laser microscopy. These findings assisted in deposition of iron nano particles on chickpea husk. Optimum adsorbent and initial phenolic concentration were calculated as 0.25g and 40ppm. The result indicated that mono layer, heterogeneous and adsorbent-adsorbate interactions observed when phenolic compounds interacts with adsobents. Adsorption was followed by Langmuir isotherm with maximum adsorption (K) of 84.033 mg/g, highest value of adsorption coefficient (p) of 0.362 and highest value of correlation coefficient (R2) of 0.992. R2 in Freundlich isotherm results was 0.999 which indicated the phenolic compounds were absorbed into the surface. The Tempkin isotherm study shows R2 value of 0.989 for adsorption of phenolic compounds. But other isotherms for phenolic compounds adsorption did not much fit. Phenolic compounds removal rates display pseudo 2nd order kinetics, giving the rate limiting step in adsorption on the surfaces. Hence, iron based nano particles deposited agro-waste chickpea husk is excellent adsorbent for the removal of phenolic compounds from wastewater.
Development of Acid Modified Clay for the Treatment of Simulated Textile Dye Effluents
Authors: O. Aderemi B. , O.R.A. Iyun , A.P. Adelana 
Published: February 2022

Abstract
The physiochemical properties of Natural Bentonite Clay (NBC) were modified in this work to increase its adsorption performance. The NBC was mined from Fika town in Yobe State and thereafter subjected to beneficiation to obtain various particle sizes. The modified NBC and Activated Bentonite Clay (ABC) were characterized using X-ray fluorescence to determine the elemental assay of the samples, Fourier transform infrared (FTIR) spectroscopy for the determination of the effect of acid attack and the adsorbate Braunner-Emmet-Teller (BET) method for surface area determination was conducted on the clay sample before and after modification procedure. The surface areas of the adsorbents before and after modification were found to be 160.40 m2/g and 126.50 m2/g for ABC and NBC respectively. The raw and the modified samples had an adsorption capacity of 12.55 and 74.98 mg/g which were used to purify the simulated textile wastewater to investigate their adsorptive performance. The equilibrium data were fitted in Langmuir, Freundlich and Temkin adsorption isotherm models with the aid of origin 9 software using two statistical parameters- the correlation coefficient R and Sum of Square Errors SSE. Results showed the experimental data was best fitted in the Langmuir isotherm model where R values of ABC was consistently higher for dye 1-dye 4 than that of NBC. The SSE of ABC was also found to be consistently lower for all dye adsorption than that of corresponding ABC.
Myeloid-related protein 8/14 in plasma and serum in patients with new-onset juvenile idiopathic arthritis in a real-life setting
Authors: Keskitalo Paula L , Kangas Salla M , Sard Sirja , Pokka Tytti , Glumoff Virpi , Kulmala Petri , Vähäsalo Paula 
Published: February 2022

Abstract
Objective: The aim of this study was to analyze the usefulness of myeloid-related protein 8/14 (MRP8/14) in the prediction of disease course in a real-life setting for patients with new-onset juvenile idiopathic arthritis (JIA), to identify the relationship between MRP8/14 and disease activity using the physician’s global assessment of disease activity (PGA), and determine whether the MRP8/14 levels measured in serum and plasma are equally useful.Methods: In this prospective follow-up study, 87 new-onset non-systemic JIA patients were studied. Blood and synovial fluid samples were collected prior to any antirheumatic medication use. MRP8/14 was measured from serum (S-MRP8/14), plasma (P-MRP8/14), and synovial fluid samples using ELISA. Results: The baseline MRP8/14 blood levels were significantly higher in patients using synthetic antirheumatic drugs than in patients with no systemic medications at one year after diagnosis in serum (mean 298 vs. 198 ng/ml, P<0.001) and in plasma (mean 291 vs. 137 ng/ml, P=0.001). MRP8/14 levels at the time of JIA diagnosis were higher in patients who started methotrexate during 1.5-year follow-up compared to those who achieved long-lasting inactive disease status without systemic medications (serum: mean 298 vs. 219 ng/ml, P=0.006 and plasma: 296 vs. 141 ng/ml, P=0.001). P-MRP8/14 was the most effective predictive variable for disease activity (by PGA) in linear multivariate regression model (combined to ESR, CRP, leukocytes, and neutrophils), whereas S-MRP8/14 was not significant. Conclusions: Blood MRP8/14 levels at baseline seem to predict disease course in new-onset JIA patients. P-MRP8/14 might be superior to S-MRP8/14 in assessing disease activity at the time of JIA diagnosis.
Are Serum Levels of Inflammatory Markers Associated With the Severity of Symptoms of Bipolar Disorder?
Authors: Wu Xiuhua , Chen Zhongcheng , Liao Yingtao , Yang Zhihua , Liang Xiaolin , Guan Nianhong , Gan Zhaoyu 
Published: February 2022

Abstract
Background: To explore the relationship between serum levels of inflammatory markers and symptomatic severity of bipolar disorder (BD).Material and Methods: A cross-sectional study was conducted on 126 BD patients with current depressive episode (BDD), 102 BD patient with current mixed or (hypo)manic episode (BDM) and 94 healthy controls (HC). Fasting serum levels of CRP, leptin (LEP), adiponectin (ADP), visfatin (VIS), TNF-α, IL-2, IL-6, IL-10, IL-17), and monocyte chemoattractant protein-1 (MCP-1) were measured with enzyme-linked immunosorbent assay (ELISA). Symptomatic severity of BD was assessed with HAMD-17 and YMRS. Generalized linear model was used to determine the association between the serum levels of inflammatory markers and symptomatic severity of BD. Results: The serum levels of IL-6, IL-10 and IL-17, and the IL-6/IL-10 ratio were significantly lower in mild BDD than in HC. In moderate BDD, the serum levels of MCP, IL-6 and IL-17 were significantly lower than in HC. In severe BDD, the serum level of ADP, MCP-1, IL-10 and IL-17and the IL-17/IL-10 ratio were significantly lower than in HC. The serum levels of TNF-α and the IL-6/IL-10 ratio were significantly higher in mild BDM than in HC. In moderate BDM, the serum level of VIS, IL-2, and IL-17 were significantly higher than in HC, but the IL-6/IL-10 ratio was significantly lower than in control. In severe BDM, the serum levels of IL-6 and IL-17 and the ratios of IL-6/IL-10 and IL-17/IL-10 were significantly lower than in HC, but the neutrophil/lymphocyte ratio was significantly higher than in HC. Conclusions: In BDD, immune-inhibition is persistently predominant, while in BDM, immune system is first activated then inhibited with the worsening of the symptoms. The dynamic change of serum inflammatory markers might help stage BD and guide the future immune treatment of BD.
Therapeutic Recreation Camps for Youth with Childhood-Onset Systemic Lupus Erythematosus: Perceived Psychosocial Benefits
Authors: Saez Cristina , Nassi Lorien , Wright Tracey , Makris Una E. , Kramer Justin , Bermas Bonnie L. , Solow Elizabeth Blair , Bitencourt Nicole 
Published: February 2022

Abstract
Background: The psychosocial burden of chronic disease can be substantial for adolescents with childhood-onset systemic lupus erythematosus (cSLE). Current literature is scarce on interventions that can improve psychosocial outcomes for this population. Therapeutic recreation camps have been proposed as a beneficial experience for chronically ill pediatric populations. However, their effective components have not been well characterized in patients with cSLE. In this study, we sought to understand the various components of the camp experience for adolescents with cSLE from both the patient and parent perspective.Methods: We recruited patients with cSLE who had participated in one or more annual, weekend-long recreational lupus camp(s) near Dallas, Texas. Semi-structured in-depth telephone interviews were conducted from March-June 2020 with both the patients and parents. Questions focused on overall patient experience, psychosocial impact of camp participation, coping skills gained, and opportunities to prepare for the transition from pediatric to adult care. Interviews were coded and analyzed using inductive thematic analysis.Results: We interviewed 9 current and former campers (ages 16-24), including a current camp counselor, and 3 of their parents separately. Reported benefits included a positive impact on social support through peer bonding, opportunities to develop coping mechanisms through structured activities and peer/medical staff interactions, opportunities for education about the cSLE disease experience, improved adherence through peer modeling, overall increase in self-efficacy, and better parental insight into the patient experience. Participants also provided suggestions for expansion and improvement in program development to optimize educational opportunities for both campers and parents. In addition, they advocated for longitudinal social support and community building.Conclusions: In this qualitative study, in which cSLE patients and their parents reflected on their experiences with therapeutic recreation camps, we found several perceived benefits impacting the patient and parent experience. Participants expressed a desire for more educational opportunities that could contribute to their successful transition from pediatric to adult care. Further studies are needed to demonstrate the effects of therapeutic recreation camps on the psychosocial health of this population.
Work-Related Musculoskeletal Pain of The Neck, Shoulders And Back Among Dentists At The Dental Hospital of The University Of Barcelona: A Cross-Sectional Study
Authors: Bayona-Baanders  , O Camps-Font , B Traboulsi-Garet , Sánchez-Garcés  
Published: February 2022

Abstract
Background: Musculoskeletal pain and disorders represents one of the greatest problems of dental professionals. The present study aimed to make an assessment of the work-related musculoskeletal pain (WRMP) of the neck, shoulders and back of the professors at the Dental Hospital of the University of Barcelona (DHUB) during the last 12 months. Methods: A cross-sectional study was performed. WRMP were assessed using validated questionnaires. Descriptive and bivariate analysis of the data were performed. Results: 165 teachers received the survey, 70 responded and 43 fulfilled the inclusion criteria. 86.05% of respondents reported WRMP during the last 12 months, with shoulders being the most common location. 83.78% of the dentists had gradual pain of moderate intensity. Nearly one-third of these periods of pain had negative consequences. Extreme cervical torsions and flexions during work have been found to be associated with WRMP in the shoulders. In addition, Body Mass Index (BMI) was related to lower back WRMP. Conclusions: Excessive cervical twists and flexions are predictors of shoulders’. A high BMI can be considered a trigger factor of lower back WRMP. Several strategies could reduce the impact of factors associated with WRMP. Further research is needed to prevent WRMP in dentists.
Impact of Urban Innovation on Urban Green Development in China's Yangtze River Economic Belt: Perspectives of Scale and Network
Authors: Tan Feifei , Yang Longxue , Lu Zhaohua , Niu Zhiyuan 
Published: February 2022

Abstract
Understanding whether and how urban innovation offers a sound solution to the dilemma of urban green development, is a crucial response to mitigate the detrimental effect on natural resources and environment for transitioning to sustainable urban development. To address the critical issue, we propose urban green development evaluation index system, and then examine how the urban innovation affect urban green development from the perspectives of government-scale, enterprise-scale and spatial correlation network, all of which are originally applied in the 108 cities of Yangtze River Economic Belt of China (YREB) during period 2006-2016. The evaluation results show that urban innovation promote urban green development, and both government-scale and enterprise-scale contribute to the effects. The constructed spatial correlation network of urban innovation illustrates the network structural form and reveals the network property, and further results tell that increasing network density and centrality would promote green development obviously. More specifically, the network density of urban innovation has been tied to the enhancement of urban green development, which is more significant in middle reaches than in lower and upper reaches of YREB. Similarly, optimizing the network’s degree centrality and closeness centrality can help facilitate urban green development in whole YREB. Thus, the research findings would provide new insights into the essence and driving forces from various scale and hidden network when exploring and seeking urban green development path.
J-shaped Association Between Serum Potassium and 30-day Mortality in Heart Failure: a Secondary Analysis of Cohort Study
Authors: Xu Huan Ying , Jiang Zi Qing , Chen Ying , Zuo Jun Ling , Wu Su Zhen , Zhou Xiao Liang 
Published: February 2022

Abstract
Background: Multiple observational studies suggest that the association between serum potassium and mortality is U-shaped in heart failure patients, but mostly failed to control for potential confounders of other electrolytes. We explored serum potassium in relation to 30-day mortality in heart failure patients by controlling serum sodium and calcium.Methods: Data were drawn from Electrolyte imbalances in an unselected population in an emergency department: a retrospective cohort study, Dryad, Dataset, https://doi.org/10.5061/dryad.f3h26j3. This study involved 31,966 patients aged 18 years or older at the emergency department in Diakonhjemmet Hospital in Oslo, Norway, between January 1, 2010 and December 31, 2015. 30-day mortality was examined according to seven predefined potassium levels: 2.60-3.40(hypokalaemia), 3.5–3.8, 3.9–4.1, 4.2–4.4, 4.5–4.7, 4.80-5.00, and 5.1–7.4(hyperkalemia) mmol/L. We estimated the risk of 30-day mortality using multivariable logistic regression, with serum potassium at 4.2–4.4 mmol/L as reference. Results: A total of 1810 patients were included, and 258 (14.25%) patients died within 30-day. After multivariable adjustment, the 30-day mortality significantly increased for patients with hyperkalemia (OR=2.18, 95% CI: 1.32,3.59), but not with normal serum potassium levels: 4.8-5.0mmol/L (OR=1.08, 95% CI: 0.62,1.87) , 4.5-4.7mmol/L (OR=1.06, 95% CI: 0.67,1.68), 3.9-4.1mmol/L (OR=1.01, 95% CI: 0.65,1.58), 3.5-3.8mmol/L (OR=0.71, 95% CI: 0.42,1.20), nor with hypokalaemia (OR=0.89, 95% CI: 0.44,1.80). A J-shaped relationship between serum potassium and 30-day mortality was found, with a cut-off point at 4.8 mmol/L. When serum potassium exceeded 4.8 mmol/L, the risk of 30-day mortality increased 192 % for each 1 mmol/L increase in serum potassium (OR=2.92, 95CI: 1.74,4.89). Conclusions: J-shaped association between serum potassium and 30-day mortality in heart failure was found, with increased mortality when serum potassium exceeded 4.8 mmol/L.