bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence and Risk Factors of Workplace Violence Against Emergency Department Nurses in China
Authors: Lei Zihui , Yan Shijiao , Jiang Heng , Feng Jing , Han Shuyang , Herath Chulani , Shen Xin , Min Rui , Lv Chuanzhu , Gan Yong 
Published: August 2022

Objectives: We aim to find out the prevalence, characteristics, and predictors of workplace violence (WPV) against current Chinese emergency department (ED) nurses.Methods: A cross-sectional survey of 20,136 ED nurses was conducted in 31 provinces in China between July and September 2019. Descriptive analyses were used to examine the prevalence and characteristics of WPV. Chi-square analysis and Binary logistic regression analysis were used to identify the predictors of WPV.Results: During the past 12 months, there are 79.39% of ED nurses exposed to any type of WPV, including 78.38% and 39.65% exposed to nonphysical and physical violence, respectively. Binary logistic regression analysis shows that ED nurses who were male, had bachelor’s degrees, had average monthly salary between 5,001 and 12,000, worked in central China, had higher professional titles, were more experienced, arranging shift work, and had higher work stress were more likely to experience WPV.Conclusion: A relatively high prevalence of WPV against Chinese ED nurses has been revealed in this study. The characteristics and predictors of WPV remind us to take positive measures to reduce WPV.
Drawing on Adolescent Psychology to Achieve Tobacco-Free Generations
Authors: Berrick Jon 
Published: August 2022

Background: In 2021, the European Union called for creation of a “tobacco-free generation.” We consider the means to this end. The persistence of youthful noncompliance with current minimum age laws (leading to widespread subsequent addiction, morbidity and mortality) raises questions whether such laws are truly aligned with adolescent psychology.Evidence: The ubiquity of minimum-age laws limits direct evidence of their effectiveness, so we seek indirect evidence. Qualitative findings originally intended for tobacco manufacturers indicate counterproductive aspects of minimum-age laws. Further evidence about adolescent reactions is provided by a recent review and meta-analysis of greater youth defiance of under-age laws than whole-of-life laws in the domain of motorcycle helmets.Policy Options and Recommendations: As an alternative to minimum-age laws, we consider the Tobacco-Free Generation proposal (TFG), which phases out sales on an age cohort basis and has recently gained prominence.Conclusion: The Tobacco-Free Generation proposal (TFG) seems well aligned with adolescent psychology, and is therefore especially worthy of attention. It has recently been introduced or endorsed by a number of jurisdictions, both local and national.
Cancer-Associated Stromal Fibroblast-Derived Transcriptomes Predict Poor Clinical Outcomes and Immunosuppression in Colon Cancer
Authors: Wang Jie , Akter Rehana , Shahriar Md. Fahim , Uddin Md. Nazim 
Published: August 2022

Background: Previous studies revealed that colonic cancer-associated fibroblasts (CAFs) are associated with the modulation of the colon tumor microenvironment (TME). However, identification of key transcriptomes and their correlations with the survival prognosis, immunosuppression, tumor progression, and metastasis in colon cancer remains lacking.Methods: We used the GSE46824, GSE70468, GSE17536, GSE35602, and the cancer genome atlas (TCGA) colon adenocarcinoma (COAD) datasets for this study. We identified the differentially expressed genes (DEGs), Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, hub genes, and survival-associated genes in colon cancer. Finally, we investigated the correlation of key genes with the survival prognosis, immunosuppression, and metastasis.Results: We identified 246 common DEGs between the GSE46824 and GSE70468 datasets of colonic CAFs, which included 72 upregulated and 174 downregulated genes. The upregulated pathways are mainly involved with cancers and cellular signaling, and downregulated pathways are involved with immune regulation and cellular metabolism. The search tool for the retrieval of interacting genes (STRING)-based analysis identified 15 hub genes and 9 significant clusters in colonic CAFs. The upregulation of CTHRC1, PDGFC, PDLIM3, NTM, and SLC16A3 and downregulation of FBN2 are correlated with a shorter survival time in colon cancer. The CTHRC1, PDGFC, PDLIM3, and NTM genes are positively correlated with the infiltration of tumor-associated macrophages (TAM), macrophages, M2 macrophages, the regulatory T cells (Tregs), T cell exhaustion, and myeloid-derived suppressor cells (MDSCs), indicating the immunosuppressive roles of these transcriptomes in colon cancer. Moreover, the CTHRC1, PDGFC, PDLIM3, NTM, and SLC16A3 genes are gradually increased from normal tissue to the tumor and tumor to the metastatic tumor, and FBN2 showed the reverse pattern. Furthermore, the CTHRC1, FBN2, PDGFC, PDLIM3, and NTM genes are positively correlated with the metastatic scores in colon cancer. Then, we revealed that the expression value of CTHRC1, FBN2, PDGFC, PDLIM3, NTM, and SLC16A3 showed the diagnostic efficacy in colonic CAFs. Finally, the expression level of CTHRC1, PDGFC, and NTM genes are consistently altered in colon tumor stroma as well as in the higher CAFs-group of TCGA COAD patients.Conclusion: The identified colonic CAFs-derived key genes are positively correlated with survival prognosis, immunosuppression, tumor progression, and metastasis.
Investigation of the Application of Coagulants in Case of Domestic Greywater Fraction
Authors: Murguly Zsófia , Bodnár Ildikó 
Published: August 2022

Abstract
During our research work, we examined the removal of contaminants from synthetically produced bathing waters using different coagulants and studied the efficiency and the mechanism of coagulation-flocculation processes in detail. In our work, we performed experiments with two different types of coagulants (iron(III) chloride and polyelectrolyte) and compared their efficiencies. The zeta potential and its change were monitored as a qualifying parameter while other water quality parameters were also analyzed. In our experiments, a newly acquired flocculator device was also used to study the coagulation-flocculation processes of larger volume samples. The main goal of our research is to promote the sustainable management of drinking water quality and to study the bathing water reuse possibilities.
High Heat Input Welding of NSSC 2120 Type Lean Duplex Steel
Authors: Simon Soma Csaba , Varbai Balázs 
Published: August 2022

Abstract
Duplex stainless steels offer a high strength alternative to stainless steel, while providing excellent corrosion resistance, due to their dual-phase microstructure. This microstructure can be significantly influenced during welding, thus the maximum recommended heat input is usually 2.5 kJ/mm. In this research, we inspected the high heat input (3 kJ/mm) weldability of NSSC 2120 lean duplex stainless steel, which is designed and developed specifically for this purpose. The welds were evaluated by metallographic techniques and corrosion tests. It was found the NSSC 2120 grade can be welded with high heat input without deterioration in the phase balance and microstructure.
Disruption to the doctor–patient relationship in primary care: a qualitative study
Authors: Eggleton Kyle , Bui Nam , Goodyear-Smith Felicity 
Published: August 2022

BackgroundStarfield described the importance of system-level components of primary care (first contact, continuous, comprehensive, coordinated), on countries’ health systems. It is postulated that, at the individual level, interpersonal interactions and relationship-centred care are central to primary care.AimTo explore the impact of COVID-19 on disruption to the doctor–patient relationship and subsequent development of new models of care.Design & settingA series of 11 cross-sectional surveys of New Zealand (NZ) urban and rural primary care doctors, nurses, and managers, from May 2020 to February 2021, to understand and monitor responses to the pandemic.MethodUsing inductive content analysis, cumulated qualitative data from doctors were examined through the lenses of the doctor–patient relationship, its disruption, and resulting changes in models of care.ResultsThere were 1519 responses to the surveys, representing 482 unique participants. The majority (86%) of responses were from doctors. The following four key themes emerged: moving to transactional consultations; task-shifting with team changes; creating a production line; and diminished communication and coordination across services.ConclusionThe advent of the pandemic led to severe and ongoing strain on practices requiring rapid change to the model of care. Team members took on new roles for triaging, testing, and separating patients with respiratory and non-respiratory symptoms. There was a rapid move to telehealth, with policies developed on where face-to-face consultations were necessary. Practice strain was exacerbated by disruption to coordination with secondary and other referral services. As new models of general practice develop, further disruptions to development of doctor–patient relationships must be avoided. This work extends Starfield’s system-level paradigm to the individual level, with the core value of primary care the doctor–patient relationship. Successful sustainable models are likely to be where relationships are treated as of central importance.
THE EFFECT OF SOCIAL MEDIA MARKETING ON PURCHASE INTENTION IN IMPROVING TOURISM SECTOR IN BATAM
Authors: Putra Edy Yulianto , Aprilson Leonardo 
Published: August 2022

This study aims to analyze the effect of social media marketing on purchase intention, as well as the relationship with brand awareness, brand image, and e-wom in the Batam City hospitality industry. The dependent variable in this study is purchase intention. The independent variables consist of social media marketing, brand image, e-wom and brand awareness.
The sampling technique used in this research is purposive sampling. There are 2 types of data used in this study, namely primary data which is data received by researchers through the distribution of questionnaires to be processed. While secondary data is data collected through research articles, scientific journals, and others to meet research needs.
The results showed that social media marketing variables had a significant positive effect on purchase intention, brand awareness, brand image and e-wom. The variables of e-wom, brand awareness, brand image, and social media marketing have a significant positive effect on purchase intention. Social media marketing variables have a significant positive effect on purchase intention through mediation of brand image, brand awareness and e-wom.
THE EFFECT OF AUDIT QUALITY AND COMPANY'S FINANCIAL CONDITION ON GOING CONCERN AUDIT OPINION AT THE REGIONAL PUBLIC ACCOUNTING OFFICE OF DKI JAKARTA
Authors: Mayndarto Eko Cahyo 
Published: August 2022

The survival of the company is always associated with the ability of management to manage the company in order to survive. Going concern is the ability of a business unit to maintain its viability for a reasonable period of time, which is no more than one year from the date of the financial statements, and the role of the auditor is also responsible for the going concern audit report.
Statistical tests are used to provide an overview and description of the variables to be studied. This analysis can also be seen from the average value (mean), standard deviation, variance, maximum, minimum, sum, range, kurtosis and skewness (skew of distribution). Therefore, in this study, information will be obtained about the relationship between variables after all data is collected, and will be processed and presented in the form of data tables. The results obtained from descriptive statistics cannot be used to find conclusions broadly.
The influence of Audit Quality and the Company's Financial Condition simultaneously affects the Going Concern Audit Opinion at the Public Accounting Firm in DKI Jakarta. This is indicated by the value of Adjust R Square, which means that the dependent variable of Going Concern Audit Opinion is simultaneously influenced by the independent variables in this study, namely Audit Quality and Company Financial Condition. From the calculation results of the SPSS Version 25 program the influence of Audit Quality on Going Concern Audit Opinions shows the value of sig. In this study, the results of data analysis obtained R Square (R2), which means that the Going Concern Audit Opinion at the DKI Jakarta Public Accounting Firm is influenced by Audit Quality and the rest is influenced by other variables that are not included in this study.
ANALYSIS OF DYNAMIC SYSTEM PERIODIC SIMULATION MODEL OF STUDENT FLOWS AT SEKOLAH TINGGI ILMU EKONOMI INDRAGIRI RENGAT
Authors: Fransinatra Ziko , Saputra Raja Marwan Indra , Adjie Gerhana , Awdina Ollyfia , Putri Tri Yulia 
Published: August 2022

An essential tool for a nation's progress is education. Higher education is one of the foundations of education, and it must maintain its quality to remain competitive and accountable to its users—whether they be students, employees, or the government. Paying attention to the human resource management plan can be one way to increase quality. A dynamic system is a technique that can assist the management or the university director in choosing the best plans or policies. An analysis of the existing research on dynamic systems in higher education was done for this study. Scope identification, variable identification, model selection, and model development are all included in literature studies. To decide on human resource management strategy for raising the standard of higher education, the Causal Loop Diagram (CLD) model was developed. In reality, the number of lecturers in a study program is not taken into consideration when accepting new students for a variety of reasons. This affects not just the learning process but also the slow rate of student graduation, creating an imbalance between the number of new students and those who graduate or leave the program (DO). The goal of this project is to create a dynamic model of the rate at which students enter and leave a program of study. A dynamic system simulation model between the number of student inputs and outputs is the end result of building this model. As a decision support tool for new student admissions policies, the simulation model that is produced can be employed.
Chronic Myeloid Leukemia: Part II—Cost of Care Among Patients in Advanced Phases or Later Lines of Therapy in Chronic Phase in the United States from a Commercial Perspective
Authors: Atallah Ehab L. , Maegawa Rodrigo , Latremouille-Viau Dominick , Rossi Carmine , Guérin Annie 
Published: August 2022

Background: Tyrosine kinase inhibitors (TKIs) are the standard-of-care treatment for chronic myeloid leukemia in chronic phase (CML-CP). Despite advances in therapy, there remains a proportion of patients with CML-CP that are refractory/intolerant to TKIs, and these patients cycle through multiple lines of therapy. Moreover, even with TKIs, some patients progress to accelerated phase/blast crisis (AP/BC), which is associated with particularly poor clinical outcomes. Objectives: To describe real-world treatment patterns, healthcare resource utilization (HRU), and costs of patients with CML-CP reaching later lines of therapy or progressing to AP/BC in the United States. Methods: Adult CML patients from administrative claims data (January 1, 2000–June 30, 2019) were classified by health state: on third-line (CML-CP On Treatment), on fourth or later lines (CML-CP Post-Discontinuation), or progressed to AP/BC (CML-AP/BC). Outcomes were assessed by health state. Results: There were 296 (4620 patient-months), 83 (1644 patient-months), and 949 (25 593 patient-months) patients classified in the CML-CP On Treatment, CML-CP Post-Discontinuation, and CML-AP/BC cohorts, respectively. Second-generation TKIs (nilotinib, dasatinib, and bosutinib) were most commonly used in the CML-CP On Treatment (69.1% of patient-months) and CML-CP Post-Discontinuation cohorts (59.1% of patient-months). Three-month outpatient incidence rates (IRs) were 7.6, 8.3, and 7.0 visits in the CML-CP On Treatment, CML-CP Post-Discontinuation, and CML-AP/BC cohort, respectively, with mean costs of $597 per service. Three-month inpatient IRs were 0.6, 0.7, and 1.4 days in the CML-CP On Treatment, CML-CP Post-Discontinuation, and CML-AP/BC cohort, respectively, with mean costs of $5892 per day. Mean hematopoietic stem cell transplantation cost was $352 333; mean 3-month terminal care cost was $107 013. Discussion: Cost of CML care is substantial among patients with CML reaching third-line, fourth or later lines, or progressing to AP/BC, suggesting that the disease is associated with a significant economic and clinical burden. From third-line to fourth or later lines, HRU was observed to increase, and the incidence of inpatient days was particularly high for those who progressed to AP/BC. Conclusion: In this study, patients with CML cycling through TKIs in later lines of therapy or progressing to AP/BC experienced substantial HRU and costs, suggesting unmet treatment needs.
Da reprodução social da unidade familiar camponesa: um estudo de caso no vale do Tocantins
Authors: Ramos Júnior Dernival Venâncio , Silva Harley 
Published: August 2022

Este artigo discute os resultados de pesquisa empírica sobre uma unidade familiar camponesa localizada no norte do estado do Tocantins. O trabalho situa essa unidade familiar no contexto das regiões de expansão da produção de soja em monocultura, além de enfatizar de que maneira a reprodução social do grupo decorre de sua capacidade de mobilizar os recursos naturais renováveis disponíveis na área, bem como dos resultados do trabalho do grupo familiar. O grupo familiar constrói relações econômicas diversas, ligadas às trocas de mercado, assim como a outras formas de integração econômica fundadas em relações de domesticidade e reciprocidade (POLANYI, 2012). O texto destaca a capacidade que o grupo tem de fazer uso de técnicas de produção e reprodução simultaneamente singelas e sofisticadas, como o cultivo de quintais produtivos com notável biodiversidade, as quais, em conjunto, asseguram a sua permanência mesmo diante das condições de dificuldade.elocation-id: e2230202Recebido: 7.dez.2021 • Aceito: 19.jul.2022 • Publicado: 4.ago.2022Artigo original / Revisão por pares cega / Acesso aberto
Pengamatan Pelaksanaan Pekerjaan Plat pada Jembatan Rumah Susun Padat Karya
Authors: Hatoguan Manurung Edison , Ricardo Julius 
Published: August 2022

Pemahaman di dalam penelitian ini sangat di perlukan bagi lulusan teknik sipil, agar dapat mengetahui serta dapat membandingkan teori – teori dibangku kuliah dengan di lapangan. Selain itu juga dapat berguna bagi mahasiswa yang akan menghadapi situasi yang akan datang di kemudian hari. Oleh karena itu, Dinas Perumahan Rakyat dan Kawasan Pemukiman (DPR KP) sebagai Owner, PT. Fajar Nusa Consultant sebagai Manajemen, dan PT. Wijaya Karya Gedung sebagai Kontraktor, dengan keadaan di lapangan untuk memantapkan dan menambah pemahaman mahasiswa dalam bidang Teknik Sipil terutama bagian Jembatan di proyek pembangunan Rumah Susun Padat Karya Rorotan, Cilincing, Jakarta Utara. Penulis diberikan kesempatan untuk melakukan penelitian di proyek pembangunan Jembatan di Rumah Susun Padat Karya selama 3 (Tiga) Bulan terhitung dari tanggal 11 – Oktober – 2021 sampai dengan 11 - Januari - 2022. dan bertempat di Proyek Pembangunan Jembatan di Rumah Susun Padat Karya, Rorotan, Cilincing. Metode yang digunakan dalam penelitian ini adalah kualitatif dengan mengumpulkan data tertentu dan observasi langsung di lapangan. Hasil dari penelitian ini ialah
Perceived Stress, Breastfeeding Motivation and Breastfeeding Success among Mothers with Newborn Infants’ Hospitalization in the Neonatal Unit
Authors: ŞENER TAPLAK Ayşe , ŞENER Yeter 
Published: August 2022

Aim: This research aimed to determine perceived stress, breastfeeding motivation, and breastfeeding success and to reveal the relationship between them, among mothers with newborn infants’ hospitalization in the neonatal unit.
Materials and Methods: This cross-sectional study sampling consisted of 128 term newborn’s mothers. After obtaining the necessary permissions data were collected via introductory characteristics form, perceived stress scale, breastfeeding motivation scale, and LATCH breastfeeding assesment scale. Descriptive statistical analyzes, Mann-Whitney U test, Kruskal-Wallis, Dunn-Bonferroni, and Spearman correlation analysis were used for data analysis. P< 0.05 was considered statistically significant in all analyses.
Results: In this sample, the perceived stress was higher among primiparous mothers with newborn infant in the neonatal unit, who were older age, primary and high school graduates, nonworking, who did not receive prenatal breastfeeding training, and started breastfeeding immediately after birth. Breastfeeding motivation was higher among young mothers, university graduates, working, mothers with a planned pregnancy, and who received prenatal breastfeeding training. The results also showed that mothers who graduated from high school and university, whose pregnancy was planned, and who received prenatal breastfeeding training had higher LATCH scale scores. As perceived stress decreased, breastfeeding motivation and breastfeeding success increased, in this study (p
Mapping the X-Ray Corona Evolution of IRAS 13224-3809 with the Power Spectral Density
Authors: Chainakun Poemwai , Luangtip Wasuthep , Jiang Jiachen , Young Andrew J. 
Published: August 2022

Abstract
We develop the power spectral density (PSD) model to explain the nature of the X-ray variability in IRAS 13224–3809, including the full effects of the X-ray reverberation due to the lamppost source. We utilize 16 XMM-Newton observations individually as well as group them into three different luminosity bins: low, medium, and high. The soft (0.3–1 keV) and hard (1.2–5 keV) PSD spectra are extracted and simultaneously fitted with the model. We find that the corona height changes from h ∼ 3 r
g during the lowest luminosity state to ∼25 r
g during the highest luminosity state. This provides further evidence that the source height from the reverberation data is significantly larger than what is constrained by the spectral analysis. Furthermore, as the corona height increases, the energy spectrum tends to be softer while the observed fractional excess variance, F
var, reduces. We find that the PSD normalization is strongly correlated with F
var and moderately correlated with the PSD bending index. Therefore, the normalization is dependent on the accretion rate that controls the intrinsic shape of the PSD. While the intrinsic variability of the disk is manifested by the reverberation signals, the disk and corona may evolve independently. Our results suggest that, as the source height increases, the disk itself generates less overall variability power but more high-frequency variability resulting in the PSD spectrum that flattens out (i.e., the inner disk becomes more active). Using the luminosity-bin data, the hint of the Lorentzian component is seen, with the peak appearing at lower frequencies with increasing luminosity.