bluuebunny/crossref_metadata_2025_split huggingface dataset:
Understanding microbial networks of farm animals through genomics, metagenomics and other meta-omic approaches for livestock wellness and sustainability – A Review
Authors: Wani Atif K. , Hashem Nesrein M. , Akhtar Nahid , Singh Reena , Madkour Mahmoud , Prakash Ajit 
Published: March 2022

Abstract
The association of microorganisms with livestock as endosymbionts, opportunists, and pathogens has been a matter of debate for a long time. Several livestock-associated bacterial and other microbial species have been identified and characterized through traditional culture-dependent genomic approaches. However, it is imperative to understand the comprehensive microbial network of domestic animals for their wellness, disease management, and disease transmission control. Since it is strenuous to provide a niche replica to any microorganisms while culturing them, thus a substantial number of microbial communities remain obscure. Metagenomics has laid out a powerful lens for gaining insight into the hidden microbial diversity by allowing the direct sequencing of the DNA isolated from any livestock sample like the gastrointestinal tract, udder, or genital system. Through metatranscriptomics and metabolomics, understanding gene expression profiles of the microorganisms and their molecular phenotype has become unchallenging. With large data sets emerging out of the genomic, metagenomic, and other meta-omics methods, several computational tools have also been developed for curation, assembly, gene prediction, and taxonomic profiling of the microorganisms. This review provides a detailed account of the beneficial and pathogenic organisms that dwell within or on farm animals. Besides, it highlights the role of meta-omics and computational tools in a comprehensive analysis of livestock-associated microorganisms.
Zinc-binding proteins in stallion seminal plasma as potential sperm function regulators
Authors: Mogielnicka-Brzozowska Marzena , Piątkowska Elżbieta , Fraser Leyland , Cichowska Aleksandra Wiktoria , Zalecki Michal , Kraziński Bartłomiej Emil , Słowińska Mariola , Kordan Władysław 
Published: March 2022

Abstract
Sperm functions may be influenced by seminal plasma (SP) proteins with affinity to zinc ions. The aim of the study was to isolate and characterise zinc-binding proteins (ZnBPs) from stallion SP using proteomic tools. Zinc-binding proteins were isolated from the SP of eight stallions by zinc-affinity chromatography. They were analysed in the SDS-PAGE system, and peptide extracts were prepared. Samples of ZnBPs isolated from stallion SP were injected onto the nLC-1000 nanoflow HPLC system coupled via a nano-electrospray ion source to the Orbitrap Elite FTMS mass spectrometer (Thermo Fisher Scientific). Raw MS data were analysed using MaxQuant software with label-free quantification (LFQ). Protein sequences were obtained from the UniProt database. Forty-seven proteins in ZnBPs were annotated in a gene ontology (GO) analysis. The LFQ intensity analysis of individual proteins revealed that ZnBPs comprised mainly clusterin (CLU, 27%), serin protease inhibitor F1 (SERPINF1, 13%), actin, cytoplasmic 1 (ACTB, 9%), nucleobindin 2 (NUCB2, 8%) and polymeric immunoglobulin receptor (PIGR, 6%). This is the first proteomic study to analyse ZnBPs in stallion SP. The present findings show that ZnBPs in stallion SP could play an important role in the regulation of sperm function.
Polydrusus aeratus (Coleoptera: Curculionidae: Entiminae): a potential pest of young coniferous stands
Authors: Fiala Tomáš , Holuša Jaroslav 
Published: March 2022

Abstract

Polydrusus aeratus Gravenhorst, 1807 is a pest of both coniferous and deciduous trees in forests. It is widespread throughout the Czech Republic from the lowlands to the mountains. Adult beetles occur from April to September. In the western Czech Republic, a number of 1- to 2-m tall Abies alba were recently damaged by P. aeratus adults at an altitude of 750 m. P. aeratus can damage older saplings that were damaged as young saplings by the pine weevil. The damage caused by P. aeratus is so for rather small but should not be neglected by foresters. As the ongoing climate change modifies the relationship between trees and pests, also currently indifferent species may become dangerous for forests in near feature. Therefore, scientists would focus also on relatively less dangerous species of pests, especially insects. Possible methods for controlling of P. aeratus are suggested as main output of the study.
Chronic stress-induced immune dysregulation in breast cancer: Implications of psychosocial factors
Authors: Chen Xiuyun , Wang Mozhi , Yu Keda , Xu Shouping , Qiu Pengfei , Lyu Zhidong , Zhang Xinwen , Xu Yingying 
Published: March 2022

Abstract
Chronic stress refers to continuous emotional changes and psychological pressure that individuals experience when they are unable to adjust and stabilize the internal environment over an extended period. It can increase the pressure on endocrine mediators and cytokines in the circulation, as well as tissues throughout the hypothalamic-pituitary-adrenaline (HPA) axis and sympathetic nervous system (SNS); thus, evolving the internal environment of the tumor. This review assesses several key issues, involving psychosocial factors, and integrates clinical, cellular, and molecular studies—as well as the latest research progress—to provide a mechanistic understanding regarding breast oncopsychology. We propose that chronic stress contributes to large individual diferences in the prognosis of breast cancer survivors because they change the basic physiological processes of the endocrine and immune systems, which in turn regulate tumor growth. The study of psychological and physiological reactions of breast cancer patients suggests a new idea for psychological intervention and clinical treatment for breast cancer patients.
Hyperthyroidism in the Domestic Cat (Felis Catus): Informed Treatment Choice Based on Survival Analysis
Authors: Mata Fernando , Bhuller Ravneet 
Published: March 2022

Abstract
Hyperthyroidism is the most frequently diagnosed endocrine disorder in cats. Therapy may include pharmacological, surgical (thyroidectomy), radioactive (iodine), and dietary treatment. The choice of treatment is believed to be strongly influenced by the veterinarian’s experience, level of education, and knowledge of the current scientific literature. The history of survival rates can affect the decision for treatment by both the veterinarian and the owner. This study aimed to explore the longevity in cats diagnosed with hyperthyroidism and to identify significant variables which affect survival rates by using retrospective data from the practice. A multivariate Cox regression was applied with the following results: surgical thyroidectomy and methimazole medication produced similar longevity (median 23.5 months, P>0.05); Domestic Short Hair cats survived longer than pure breeds (median 27.2 vs 9.4 months, P<0.05); as do cats without chronic renal disease (median 28.1 vs 6.2 months, P<0.001); and those with low activities of alanine aminotransferase (median 27.1 vs 17.0 months, P<0.01). Hyperthyroidism is comorbid with renal diseases, but no cumulative effect was found on survivability. There was no difference in survival rates between surgical and pharmaceutical treatment, therefore the discussion of treatment options with owners can focus on other factors (e.g., cost, owners’ compliance, cats’ tolerance to medication, presence of comorbidities). We propose that surgery may be the preferred treatment when the survival rates are expected to be higher than one year. This would avoid high costs and potential side effects of medication.
Knowing When and How to Trust Superiors’ Decisions: Toward a Conceptual Model of Subordinate Managers’ Behavior
Authors: Kotsev Emil 
Published: March 2022

Abstract

Background/Purpose: The study explores subordinate managers’ propensity to trust superiors’ decisions. Its purpose is twofold: first, to provide lower-level managers with a tool to know when and how to trust superiors’ decisions for a better organizational performance, and second, to lay the foundations for the development of a conceptual model of subordinate managers’ behavior.

Methods: The research philosophy adopts an inductive content analysis perspective. A mixed-methods research design is applied, using both qualitative and quantitative approaches. Data is collected through questionnaire, focus groups, interviews, and literature review. A total number of 219 managers from eight Bulgarian business organizations filled the questionnaire and 92 of them participated in group discussions and interviews.

Results: The majority of the managers surveyed tend to trust their immediate superiors. As a result of group discussions, the main advantages and disadvantages of managers with opposing attitudes toward trust are identified. A decision tree model of subordinate manager’s appropriate behaviors is proposed.

Conclusion: Inferior managers can have an active role in managing trust in their superiors’ decisions. Several situational factors, including superior’s competence and integrity, and organizational culture, determine the degree of trust that the subordinate manager should observe concerning the decisions and requests of the immediate superior.
Kikuchi-Fujimoto disease and systemic lupus erythematosus – an enigmatic association for clinicians and pathologists: Case report and short literature review
Authors: Tarabichi Shirley , Nicola Andreea Alexandra , Radu Lucia , Enache Simona , Busuioc Constantin Ioan , Moldovianu Ana-Maria , Nitu Andra-Florina , Predeteanu Denisa , Sarafoleanu Codrut 
Published: March 2022

Abstract
Kikuchi-Fujimoto disease or histiocytic necrotizing lymphadenitis is a benign condition of the lymphatic tissue whose cause has not been fully elucidated. Although it has been thought that various viral infections are involved in the onset of the disease, its immunological characteristics expressed by the proliferation of cytotoxic CD8-positive T lymphocytes and histiocytic phagocytosis place it at the border of autoimmunity. Sharing immunological mechanisms, clinical manifestations, and epidemiological data (both are described in young women) with systemic lupus erythematosus (SLE), the association of the two pathologies represents a challenge for both clinicians and pathologists.
We present the case of a young woman with SLE with immunological, haematological and articular involvement, who associates a few months after diagnosis the significant swelling of the submandibular glands and latero-cervical lymphadenopathy. Histopathological and immunohistochemical examinations subsequently certify the diagnosis of histiocytic necrotizing lymphadenitis associated with the autoimmune disease.
Fluorescent border diagnosis and surgical treatment of the malignant process of external nose skin
Authors: Yevcheva Anhelina , Pukhlik Serhii , Vicheva Dilyana 
Published: March 2022

Abstract

OBJECTIVE. The purpose of the study was to find out the diagnostic value of the Photolon® as a fluorescent visualization of the borders of malignant lesions of the external nose, with the aim of radical surgical removal of the tumor.

MATERIAL AND METHODS. During the period from 2016 until 2018, 30 patients with malignant neoplasms of the external nose were examined and operated on in the Otolaryngology-Head and Neck Department. During the study, patients underwent surgical removal of tumors by using a complex of anemic Klein’s solution and fluorescent imaging of the lesion in 15 patients, while 15 patients were operated on without using Klein’s solution and fluorescent imaging.

RESULTS. Observation in the postoperative period showed that, in the group of patients who underwent fluorescent imaging with adding anemic Klein’s solution, the postoperative period was satisfactory, and no signs of recurrence were observed. In the group operated on without fluorescent imaging and without conducting anemic Klein’s solution, after two years 4 (26.6%) patients were diagnosed with a superficial recurrence of skin cancer at the border of the cartilage and bone.

CONCLUSION. The authors provide suggestions for the effectiveness of the use of a complex of fluorescent imaging of the border of the tumor lesion and prophylactic anemic solution in the surgical removal of the tumor of the outer nose.
METHODS OF SEED-GROWING OF THE COTTON THE APPLIED IN WORLD
Authors: Турсоатов С. , Мамарахимов Б.И. 
Published: March 2022

В статьи приведен обзор и сопоставление методов семеноводство хлопчатника. В мире существуют разные способы отбора и заготовки семян хлопчатника в целях семеноводства. Сопоставление методов семеноводство хлопчатника применяемых за рубежом дает возможности адаптации систему региона к мировому практику.
In articles the review and comparison of methods cotton seed-growing is resulted. In the world there are different ways of selection and preparation of seeds of cotton with a view of seed-growing. Comparison of methods seed-growing of cotton applied in world practices gives possibilities of adaptation region system to world expert.
Perang Teluk III : Dimensi Politik dan Bisnis
Authors: Soedradjat Setyo 
Published: March 2022

Untuk kesekian kali, kawasan Teluk menjadi ajang pertempuran. Dua kali sudah Irak mengalami invasi. Invasi pertama oleh pemimpin Amerika pada tahun 1991 dan setengah tahun yang lalu dilakukan lagi oleh Amerika Serikat lagi plus Inggris dan lain-lain, invasi kali ini Amerika dipimpin oleh Bush yunior. Invasi juga pernah dilakukan oleh Irak (ke Kuwait) dalam Perang Teluk II. AS Bush Pimpinan yang dibantu para sekutunya, kemudian menyerang Irak habis-habisan yang diikuti oleh embargo ekspor minyak Irak. Jauh sebelumnya, mesin-mesin dan amunisi perang juga sudah berlangsung bertahun-tahun karena perang Iran Irak melelahkan itu. Invasi AS dan Inggris ke Irak dalam perang Teluk II dibantu 27 sekutunya; kali ini dimulai pada akhir Februari 2003 dan berakhir relatif singkat yakni sampai 20 Maret 2003 (sekitar 3 minggu).
Soil Mesofauna Community on Ex-Landfills Land Gunung Tugel Banyumas Regency
Authors: Susanto Susanto , Briliani Erin Putri Latifatul , Purbomartono Cahyono 
Published: March 2022

This study aims to identify and reveal the soil fauna community which includes individual counts, diversity and dominance as well as the quality of the soil environment in the former landfills Gunung Tugel land, Kedung Randu Village, Patikraja District, Banyumas Regency. The method used is purposive random sampling. Sampling was carried out for six months, during January-June 2021, six times with an interval of one month, at day (06.00 - 08.00) and night (18.00-20.00). Soil sampling and soil quality measurements were carried out at two research locations, location I in the northern and eastern areas of the ex-landfills Gunung Tugel area and location II in the western and southern areas of the ex- landfills Gunung Tugel area. The results of the sampling were identified using a microscope and referred to the book An Introduction to the Study of Insects and the book Ecology of Soil Animals. The results showed that 394 individuals of soil mesofauna were counted which belonged to 12 orders, 15 families and 17 species. The diversity index is classified as moderate, in the range of 0.970 - 1.097 with an average of 1.045. The dominance index is relatively low, ranging from 0.335 to 0.423 with an average of 0.367 and shows that no species dominates. The quality of the soil environment of the former Gunung Tugel landfills is classified as not yet feasible to support the life of the soil mesofauna.
Analisis Penyebab Banjir Rob di Kawasan Pesisir Studi Kasus: Jakarta Utara, Semarang Timur, Kabupaten Brebes, Pekalongan
Authors: Syafitri Annisa Widya , Rochani Agus 
Published: March 2022

ABSTRACTRob flooding in coastal areas is a problem that is currently very difficult to solve, especially big cities in Indonesia. This study discusses the causes of rob flood disasters to the impacts caused to inundated areas. This research uses descriptive qualitative method with the approach of study literature in conducting studies related to the cause of rob flood. The case study that became the reference of this study consisted of rob flood problems in the city of Semarang, Brebes Regency, Pekalongan, and North Jakarta. The cause of rob flooding in coastal areas is dominated by decreased land levels and rising sea levels at high tide. The impact of rob flooding is very detrimental to the community and the government. Areas affected by rob flooding are not uncommon to become slums after rob floods occur. Damage to infrastructure and public facilities is also inevitable when affected by rob flooding. This research is expected to be considered as an anticipation material for residents who are in coastal areas when facing flood rob.Keywords: Land Subsidence, Over Pumpage Of Underground Water, Rob Puddles ABSTRAKBanjir rob di kawasan pesisir menjadi permasalahan yang saat ini sangat sukar untuk diselesaikan khususnya kota-kota besar di Indonesia. Penelitian ini membahas terkait penyebab dari bencana banjir rob hingga dampak yang ditimbulkan bagi wilayah tergenang. Penelitian ini menggunakan metode kualitatif deskriptif dengan pendekatan literatur studi dalam melakukan kajian terkait penyebab banjir rob. Studi kasus yang menjadi acuan dari penelitian ini terdiri dari permasalahan banjir rob di Kota Semarang, Kabupaten Brebes, Pekalongan, dan Jakarta Utara. Penyebab dari banjir rob di kawasan pesisir didominasi oleh penurunan muka tanah dan kenaikan muka air laut pada saat terjadi pasang air laut. Dampak yang ditimbulkan dari banjir rob sangat merugikan masyarakat dan pemerintah. Kawasan terdampak genangan banjir rob tak jarang menjadi kawasan kumuh pasca banjir rob terjadi. Kerusakan infrastruktur dan fasilitas umum juga tidak dapat dihindari saat terdampak genangan banjir rob. Penelitian ini diharapkan dapat menjadi pertimbangan sebagai bahan antisipasi bagi warga yang berada di kawasan pesisir saat menghadapi banjir rob.Kata Kunci: Land Subsidence, Over Pumpage Air Bawah Tanah, Genangan Rob
Kesesuaian Lahan Permukiman Terhadap Kawasan Rawan Bencana Longsor
Authors: Firdaus Muhammad Iqbal , Yuliani Eppy 
Published: March 2022

ABSTRACTIndonesia is a country with varying regional topography conditions. This varied topography also means that Indonesia has varying slope levels as well. With the slope of this varied slope increases the potential for landslide disasters. Some areas with steep slope levels are utilized not as they should increase the risk of losses experienced in the event of a disaster. This research aims to identify and analyze the suitability of residential land to landslide-prone areas and to identify mitigation efforts against landslides. This analysis begins by identifying the factors that affect landslide disaster insecurity. After that, identify the distribution of settlements. After the two were identified, an analysis was carried out to determine the suitability of the landslide-prone settlement. Based on the analysis that has been done, then the next step is to classify landslide disaster prone areas where the number of classes obtained is 5 (five) classes. The classification of landslide disaster insanity is divided into very low, low, medium, high, and very high levels of insanity.Keywords: Settlements, Disaster Insecurity, Landslide ABSTRAKIndonesia merupakan negara dengan kondisi topografi wilayah yang bervariasi. Topografi yang bervariasi ini juga mengartikan bahwa Indonesia memiliki tingkat kemiringan lereng yang bervariasi pula. Dengan kemiringan lereng yang bervariasi ini meningkatkan potensi terjadinya tanah longsor. Beberapa wilayah dengan tingkat kemiringan lereng curam ini dimanfaatkan tidak sebagaimana mestinya sehingga meningkatkan risiko kerugian yang dialami saat terjadi bencana. Penelitian ini bertujuan untuk mengidentifikasi dan menganalisis kesesuaian lahan permukiman terhadap kawasan rawan bencana longsor serta mengetahui upaya mitigasi terhadap bencana tanah longsor. Analisis ini dimulai dengan melakukan identifikasi faktor-faktor yang mempengaruhi kerawanan bencana longsor. Setelah itu, melakukan identifikasi persebaran lokasi permukiman. Setelah keduanya diidentifikasi, maka dilakukan analisis guna mengetahui kesesuaian lahan permukiman terhdap kawasn rawan bencana longsor. Berdasarkan analisis yang telah dilakukan, maka langkah selanjutnya adalah melakukan klasifikasi kawasan rawan bencana tanah longsor dimana jumlah kelas yang diperoleh adalah 5 (lima) kelas. Klasifikasi kerawanan bencana tanah longsor terbagi menjadi tingkat kerawanan sangat rendah, rendah, sedang, tinggi, dan sangat tinggi.Kata Kunci : Permukiman, Kerawanan Bencana, Tanah Longsor
Relación entre el control de la presión arterial y la adherencia al tratamiento medida mediante el sistema de receta XXI en Granada (España)
Authors: García Corpas José P. , Pareja-Martínez Elisa , Esquivel-Prados Elisabeth , Martínez-Martínez Fernando 
Published: March 2022

Introducción: La adherencia al tratamiento ha sido identificada como uno de los factores más importantes para conseguir valores de presión arterial adecuados en pacientes hipertensos. Objetivo: Describir cuál es la adherencia de los pacientes al tratamiento antihipertensivo determinada mediante los registros de retirada de medicamentos por prescripción electrónica (Receta XXI) y estudiar la relación que existe entre dicha adherencia y el control de la presión arterial (PA).
Método: Descriptivo transversal desde mayo de 2017 hasta mayo de 2019, en 6 farmacias comunitarias de la provincia de Granada (España). Se incluyeron pacientes mayores de 18 años que tomaban al menos un medicamento antihipertensivo durante un mínimo de 6 meses. Variables principales: Control de la presión arterial y adherencia al tratamiento antihipertensivo mediante el Sistema Receta XXI.
Resultados: 95 pacientes fueron incluidos en el estudio. 49 (51,6%) no tenían controlada la PA y 29 (30.5%) paciente mostraron tener una adherencia sub-óptima. El análisis multivariante mostró que el grado de adherencia no estaba asociado a ninguna de las variables incluidas en el estudio y el control de la PA sólo estuvo relacionado con el sexo (OR: 0,044; IC95%: 0,005-0,427), con haber padecido arritmia cardiaca (OR: 0,004; IC95%: 0,000-0,106) y con padecer ansiedad (OR: 0,109; IC95%: 0,013-0,933).
Conclusión: La prevalencia de hipertensión arterial no controlada fue muy elevada (51,6%) y no hubo asociación con factores de riesgo sociodemográficos habituales como la actividad física, tabaquismo o IMC. La falta de adherencia al tratamiento también tuvo una prevalencia muy alta (30.5%) sin embargo no mostró ser factor de riesgo PA no controlada.