bluuebunny/crossref_metadata_2025_split huggingface dataset:
The value of air purification and carbon storage ecosystem services of park trees in Warsaw, Poland
Authors: Szkop Zbigniew 
Published: September 2022

Abstract
This study assessed, in monetary terms, the ecosystem services provided by trees growing in public parks and garden squares in Warsaw, Poland. It focused on the valuation of two services: air purification (measured as an annual benefit stream in EUR/year) and carbon storage (measured as a fixed value at a given point in time in EUR). The study was conducted using the Avoided Cost Method with i-Tree Eco software. The initial calculations were based on data obtained from 41 selected green spaces in Warsaw. Subsequently, the results were extrapolated to all public parks and garden squares. The findings indicate that the average economic value of the NO2, SO2 and PM2.5 pollution removal ecosystem service provided by trees in Warsaw is around 3 EUR/tree/year. On average, one hectare of a public park in Warsaw provides this service at a value of 408 EUR/ha/year, while one hectare of a garden square provides this service at a value of 347 EUR/ha/year. With regards to the carbon storage ecosystem service, the results showed that the average economic value of this service is around 170 EUR/tree. On average, one hectare of a public park provides this service at a value of 22.4 thousand EUR/ha, and one hectare of a garden square provides this service at an average value of 18.9 thousand EUR/ha. By extrapolating these results, the total value of the air pollution removal ecosystem service provided by trees growing in all public parks and garden squares in Warsaw was estimated to range from 393 to 560 thousand EUR/year. The value of the carbon storage service ranges from 23.3 to 30.2 million EUR.
Options of Treatment in SARS-CoV-2 Infections
Authors: Cristea Alexandra Maria , Cosmin Zaharia Dragos , Miron Bogdan Alexandru 
Published: September 2022

Abstract
Starting December 2019, in China, the SARS-CoV-2 infection became a local health issue, but its high infectiveness quickly turned it into a pandemic, to be declared an epidemiological emergency of international concern less than two months from identifying the first cases. Despite tremendous efforts aimed at discovering new drug classes that would slow down or stop the evolution of the COVID-19 disease and curb the number of severe cases and related complications, there is no specific antiviral treatment to date. The only efficient measure proved to be the prophylaxis, through vaccination.
Therapeutic challenges in a case of sarcoidosis
Authors: Hédi-Katalin Sárközi , Vultur Mara Andreea , Szathmáry Mioara , Budin Corina , Chiș Monica , Jimborean Gabriela 
Published: September 2022

Abstract
Sarcoidosis is a chronic systemic inflammatory disease with unknown etiology, whose diagnosis is based on suggestive symptoms/imaging, histopathological examination with non-caseous granuloma, and exclusion of other etiologies. Corticosteroid therapy is the treatment of choice for moderate/severe forms, but medication intolerance or unfavorable evolution may require immunomodulatory therapy. A 40-year-old patient known with poly-allergy was hospitalized for resting dyspnoea, dry cough, night sweats, and itching. Objective examination identifies roughened breathing, wheezing and SpO2 = 98%. Spirometry shows a medium mixed ventilatory dysfunction. Computed tomography (CT) describes multiple mediastinal lymphadenopathies and inhomogeneous hepatomegaly. Osteomedullary biopsy refutes the suspicion of lymphoma. Bronchoscopy detects bronchial hypervascularization. Due to the suggestive imaging context, a transbronchial biopsy was performed (EBUS-TBNA) from the mediastinal lymphadenopathy. Histopathological examination suggested sarcoidosis: granulomas with epithelioid histiocytes, without caseous necrosis, associated with Langerhans cells and lymphocytes. We initiated corticosteroid therapy, but the patient had an allergic reaction that required the interruption of treatment and administration of methotrexate. After eight months, the clinical and imaging aspect worsened, and we replaced the treatment with cyclophosphamide. However, side effects occurred after a few months, it was replaced with azathioprine. The patient’s condition deteriorates significantly with desaturation. We requested a consultation with the ‘Sarcoidosis Center’ in Rotterdam, which recommended treatment with anti-TNF-α or human immunoglobulin. The patient shows a slightly favorable evolution under human immunoglobulin. The poly-allergy and drug intolerance, including corticosteroid therapy, led to the initiation of immunomodulatory therapy for a young patient with moderate/severe sarcoidosis. The choice of medication was difficult due to the side effects.
DETERMINASI TOTAL BAKTERI DAN Escherichia coli PADA TELUR BURUNG PERKUTUT (Geopelia striata) YANG GAGAL MENETAS DI BEBERAPA PENANGKARAN LOKAL DENPASAR, BALI
Authors: Saputra Aryadi Millenia , Kawuri Retno , Subagio Job Nico 
Published: September 2022

Burung memiliki daya tarik yaitu memiliki warna unik dan suara merdu, termasuk jenis burung perkutut (Geopelia striata). Tingginya nilai ekonomi burung perkutut (G. striata) bagi masyarakat menyebabkan perburuan dan perdagangan satwa tersebut dilakukan secara berlebihan sehingga dapat menurunkan populasi burung di alam. Usaha konservasi yang dilakukan untuk mencegah terjadinya penurunan populasi burung di alam yaitu tempat penangkaran burung. Kontaminasi bakteri merupakan kendala selama proses perkembangbiakan burung. Tujuan dilakukan penelitian ini adalah untuk menentukan Angka Lempeng Total (ALT) bakteri dan Escherichia coli pada sampel isi dan cangkang telur burung perkutut (G. striata) yang gagal menetas dari beberapa penangkar burung lokal Denpasar, Bali. Penelitian dilakukan di Laboratorium Mikrobiologi Program Studi Biologi FMIPA Universitas Udayana. Metode yang digunakan yaitu uji ALT secara pour plate pada media Nutrient Agar (NA) dan Eosin Methylene Blue Agar (EMBA). Hasil pengujian ALT bakteri pada sampel isi dan cangkang telur diperoleh rata – rata tertinggi terdapat di penangkar III, sedangkan terendah di penangkar I. Hasil pengujian ALT Escherichia coli pada sampel isi dan cangkang telur diperoleh rata – rata tertinggi terdapat di penangkar III. Keberadaan jumlah ALT bakteri dan Escherichia coli pada sampel isi dan cangkang telur burung perkutut (G. striata) bervariasi pada setiap penangkar.
Kata kunci: Patogen, Kontaminasi Bakteri, Tahap Kematian Embrio
ANALYSIS OF CASSIAVERA FARMING DEVELOPMENT STRATEGY IN KERINCI REGENCY
Authors: Ulma Riri Oktari , Nurchaini Dewi Sri , Effran Endy 
Published: September 2022

The purpose of this study are describes general picture of Cassiavera farming in Kerinci Regency, and Identifying any strategies and alternative strategies that can be applied in developing Cassiavera farming in Kerinci Regency. Research data is sourced from primary and secondary data. Data collection techniques are taken by means of observation, in-person interview, and indepth interview. Determination of sample regions is done by the Stratified–Cluster random sampling method, where the technique combines stratafication and cluster methods. Meanwhile, the determination of farmer respondents was taken using the slovin technique. Data analysis in descriptive and SWOT analysis. The results showed that the development of Cassiavera farming in Kerinci Regency uses S-O strategy which is a combination of strength and opportunity factors, with alternative strategies that can be applied, namely maintaining the quality of Cassiavera to maintain the superior advantage of Cassiavera as Indonesia's superior export commodity to meet high market demand.
PENERAPAN PRINSIP-PRINSIP ARSITEKTUR EKSPRESIONIS DALAM PERANCANGAN THEATRE ART CENTER DI RENGAT
Authors: Ningsih Aprilliya , Faisal Gun , Rijal Muhammad 
Published: September 2022

Dalam Kehidupan manusia saat ini erat kaitannya dengan yang namanya seni dan budaya. Terutama seni teater yang menampilkan pertunjukan yang berisi dialog, akting, tarian, dan nyanyian yang dilakukan oleh para pemainnya diatas panggung. Fasilitas penunjang dan pendidikan yang berfokus pada bakat dan minat generasi muda terutama pada bidang seni teater saat ini sangat kurang diperhatikan. Hal ini mempengaruhi penurunan aktivitas pada beberapa komunitas atau sanggar teater yang sudah ada. Kurangnya fasilitas yang memadai untuk pendidikan dan pertunjukan seni teater merupakan salah satu yang melatar belakangi perencanaan dan perancangan Theatre Art Center di Rengat. RengatÂ merupakan kota yang kaya tentang adat istiadat serta kesenian teaternya, hal ini dapat dilihat dari sering diadakannya pementasan teater di beberapa gedung. Ditambah dengan banyaknya berdiri komunitas atau sanggar teater didaerah tersebut. Theatre Art Center menjadi wadah kegiatan seni teater yang berfungsi sebagai ruang edukasi dan pertunjukan, sehingga dapat mendukung minat dan bakat bagi masyarakat dalam pementasan seni teater. Tema Ekspresionis akan menerapkan ciri dan nilai dari ekspresionisme ke dalam rancangan. Tema akan diterapkan pada tapak, fasad maupun ruang di dalam bangunan.
METHODOLOGICAL APPROACH TO TEACHING THE PRINCIPLES OF TRANSCRIPTIONAL REGULATION OF INFLAMMATION AS A TYPICAL PATHOLOGICAL PROCESS AT THE DEPARTMENT OF PATHOPHYSIOLOGY
Authors: Akimov O.Ye. 
Published: September 2022

Inflammation is a typical pathological process that develops as a result of an injury and aimed at eliminating the damaging agent and restoring the integrity of the body. Students of the II (Master) level first encounter the concept of "inflammation" at the Department of Pathophysiology when studying the module I "General Pathophysiology". Basic textbooks on the discipline "Pathophysiology" comprehensively provide information on inflammation as a typical pathological process and distinguish generally accepted stages of this process, though a limited amount of data on the participation of specific transcription factors in the regulation of inflammation is represented. This causes difficulty for medical students when studying additional literature and learning lecture material. Understanding the mechanisms of transcriptional regulation of inflammation will help students to correctly diagnose the stages of this process and thus plan rational intervention to manage it. This can contribute to the quality of medical education and, in the long term, the quality of medical services.
The purpose of this work is to develop a methodological approach to teaching the principles of transcriptional regulation of inflammation at the Department of Pathophysiology. The analysis of literature sources showed a certain antagonism between NF-kB and Nrf-2 at the stage of alteration. The predominance of Nrf-2 will reduce the intensity of secondary alteration, while the predominance of NF-kB will increase it. At the stage of exudation, another important transcription factor, namely AP-1, is added to the regulation of inflammation. Its role depends on the stimulation of cells by certain regulatory agents. To provide optimal conditions for repair of the damaged area, NF-kB activation should be reduced, Nrf-2 activation should be increased, and AP-1 should be activated via p38. Methodological approach to teaching the principles of transcriptional regulation of inflammation at the department of pathophysiology should include: emphasis on the importance of specific transcription factors in the regulation of cellular processes; schematically justified relationship and functional antagonism of transcription factors NF-kB and Nrf-2 at the stage of alteration; discussion regarding the ambiguous role of the transcription factor AP-1 in maintaining and stopping exudation; evidence of the need for the predominance of Nrf-2 and AP-1 activation for the full recovery of damaged tissue during proliferation.
ANALISIS ALASAN MASYARAKAT DALAM MENGGUNAKAN JALUR PEDESTRIAN DI KOTA BANDARLAMPUNG
Authors: Perkasa Mahendra Eka , Artemisia B. Chrysvania , Murwadi Haris 
Published: September 2022

Abstract: A good city is a city that is able to make it easier for people to carry out various activities in the city while still paying attention to its environmental conditions, such as the availability of pedestrian paths. The pedestrian path is a facility that functions as a space for pedestrians to carry out various activities in a city so that they can walk comfortably and safely. With pedestrian paths, a city can become a city that is more environmentally friendly, because it can reduce emissions from using motorized vehicles that can cause air pollution in an urban environment, such as cycling and walking. The purpose of this research is to find out what reasons make the people of Bandarlampung City use the pedestrian path and to find out what types of activities make people use the pedestrian path. The method used in this study is a qualitative method, data collection was carried out by distributing online questionnaires that were distributed to some of the people of Bandarlampung City. This study found the reasons for the community in using the pedestrian path which were then grouped into two groups of reasons, namely the groups of reasons which were Activity and Non-Activity in nature. The reason group that is Activity consists of the reasons for Accessibility and Kind of Activity. The non-activity group of reasons consists of Lane Comfort and Pushers. Abstrak: Sebuah kota yang baik adalah kota yang mampu memudahkan masyarakat dalam melakukan berbagai aktivitas di dalam kota dengan tetap memperhatikan kondisi lingkungannya, seperti tersedianya jalur pedestrian. Jalur pedestrian merupakan sebuah fasilitas yang berfungsi sebagai ruang bagi pejalan kaki dalam melakukan berbagai aktivitas di suatu kota agar dapat berjalan dengan nyaman dan aman. Adanya jalur pedestrian, suatu kota dapat menjadi kota yang lebih ramah lingkungan, karena dapat mengurasi emisi dari penggunaan kendaraan bermesin yang dapat mengakibatkan pencemaran udara pada suatu lingkungan perkotaan, seperti bersepeda dan berjalan. Tujuan dari penelitian ini adalah untuk mengetahui alasan apa saja yang membuat masyarakat Kota Bandarlampung mengunakan jalur pedestrian dan mengetahui jenis kegiatan apa saja yang membuat masyarakat menggunakan jalur pedestrian. Metode yang digunakan pada penelitian ini adalah metode kualitatif, pengumpulan data dilakukan dengan menyebarkan kuisioner online yang dibagikan kepada sebagian masyarakat Kota Bandarlampung. Penelitian ini menemukan alasan masyarakat dalam menggunakan jalur pedestrian yang kemudian dikelompokkan menjadi dua kelompok alasan, yaitu kelompok alasan yang bersifat Activity dan Non-Activity. Kelompok alasan yang bersifat Activity terdiri dari kelompok alasan Accesibility dan Kind of Activity. Kelompok alasan yang bersifat Non-Activity terdiri dari Lane Comfort dan Pushers.
PENERAPAN IDENTITAS PERUSAHAAN DALAM PERANCANGAN INTERIOR: STUDI KASUS LEMBAGA BAHASA LIA PENGADEGAN
Authors: Hapsoro Nur Arief , Zahra Zetta Andalusia 
Published: September 2022

Abstract: Corporate identity is totally important to make the public identify its existence easily. Corporate identity must be applied in its interior design to directly present the visual form of the spaces to its users. The case study in this research is the interior design of Lembaga Bahasa LIA Pengadegan building. Researchers found that LIA identity is not fully applied in the space forming elements—floor, wall and ceiling. Therefore, the aim of this research is to get the public insights about the application of LIA identity on its interior design by means of questionnaire and then match the results with the respondents’ answers and the researcher’s opinion about the identity being applied. This research uses a qualitative method where data is gained by filling in questionnaire, source, and pictures. Data analysis results in a descriptive conclusion: researchers, the public and source have the same opinion about the color of LIA identity, but they have different opinion about other elements of LIA identity. Abstrak: Identitas perusahaan sangatlah penting agar perusahaan tersebut dikenal masyarakat. Identitas perusahaan harus diterapkan dalam perancangan interiornya sehingga bentuk visualnya dapat dihadirkan secara langsung untuk pengguna ruang. Studi kasus yang diangkat dalam penelitian ini adalah interior gedung Lembaga Bahasa LIA Pengadegan yang merupakan Kantor pusat sekaligus tempat kursus bahasa Inggris. Peneliti bahwa identitas LIA kurang diterapkan pada elemen pembentuk ruang-lantai, dinding dan plafon. Oleh karena itu, penelitian ini bertujuan untuk memperoleh pandangan masyarakat terhadap penerapan identitas LIA pada perancangannya melalui pengisian kuesioner, serta mencocokkannya dengan jawaban narasumber pada saat wawancara dan pandangan peneliti mengenai identitas yang diterapkan. Penelitian ini menggunakan metode kualitatif dengan pengumpulan datanya berupa pengisian kuesioner, wawancara dan foto. Data dianalisis menghasilkan kesimpulan yang berbentuk deskripsi berupa: peneliti, masyarakat, dan narasumber memiliki pandangan yang serupa terhadap warna identitas LIA, namun ketiga pihak tersebut memiliki pandangan yang berbeda terhadap elemen identitas lainnya.
POTENSI VISUAL DAN STORYTELLING EKOWISATA BUKIT PANGONAN DI ERA DIGITAL
Authors: Basuki Basuki 
Published: September 2022

Obyek wisata Bukit Pangonan Kabupaten Banyumas mempunyai potensi dalam pengembangan tujuan wisata yang hijau, sehat, alami dan lokal di era digital. Potensi visual tidak hanya terkait dengan estetika, namun juga nilai dan makna yang lebih luas, seperti: kebahagiaan, pengalaman, pengetahuan, kenangan (memori), konektivitas sosial, bahasa dan aktualisasi diri dalam bentuk narasi cerita (storytelling). Penelitian ini bertujuan untuk mengidentifikasi potensi visual obyek wisata bukit Pangonan Kabupaten Banyumas. Potensi visual yaitu visual yang unik dan bernilai dari obyek wisata tersebut. Penelitian dilakukan dengan pendekatan kualitatif eksploratif melalui studi kasus. Pengumpulan data dilakukan melalui kuesioner terbuka (open-ended), wawancara dan studi dokumen dari berbagai sumber yang terpublikasi maupun yang tidak terpublikasi. Data kemudian diolah secara kualitatif dengan metode open coding, axial coding, dan selective coding. Hasil penelitian menemukan bahwa potensi visual fisik kawasan wisata Bukit Pangonan adalah: view diatas bukit, wisata hijau-sehat-alami, dan wisata lokal. Faktor-faktor tersebut merupakan faktor unik dan bernilai yang dapat menciptakan sense of place Bukit Pangonan. Namun demikian, utilitas marjinal akan semakin menurun seiring dengan intensitas kunjungan, sehingga peran kreativitas diperlukan untuk memperkuat potensi visual branding kawasan
A new wireless actuator integrating magnetic resonance coupling with reluctance actuator
Authors: Zhang Lihui , Xia Yongming , Ma Jien , Zheng Jun , Yan Wenjun , Fang Youtong , Lu Qinfen , Gong Zhe 
Published: September 2022

The subcutaneous implant, which can realize on-demand drug release, is used for the treatments of some chronic diseases such as chronic pain, diabetes, and osteoporosis. This paper proposes a new type of wireless actuator for potential use in active implantable drug delivery systems. The proposed structure suits both wireless power well, which requires far-field flux traveling and receiving, and actuator design, which should take advantage of strong local magnetic fields. The mover in the actuator generates mechanical movement when power is transferred wirelessly to the actuator, and the mover restores to its original position when the wireless power stops. The maximum oscillation amplitude of the mover can be achieved when the ON and OFF frequency of the wireless power transfer is equal to the mechanical resonant frequency of the mover. Experimental results on a prototype actuator with 20 mm in diameter and 10.3 mm in thickness are given for validating the proposed new idea.
HE4 and CA125 serum biomarker monitoring in women with epithelial ovarian cancer
Authors: Samborski Alexandra , Miller M. Craig , Blackman Alexandra , MacLaughlan-David Shannon , Jackson Amanda , Lambert-Messerlian Geralyn , Rowswell-Turner Rachel , Moore Richard G. 
Published: September 2022

BACKGROUND: CA125 is the gold standard serum biomarker for monitoring patients with epithelial ovarian cancer (EOC). Human epididymal protein 4 (HE4) is a novel serum biomarker for EOC patients. OBJECTIVE: The objective of this trial was to examine the utility of measuring serum HE4 levels for monitoring EOC patients and to compare HE4 performance parameters to serum CA125. METHODS: A retrospective trial using residual longitudinal serum samples drawn during treatment and monitoring from EOC patients. Serum CA125 and HE4 levels were analyzed at each time point, and a velocity of change was calculated and correlated with clinical status. The null hypothesis was that HE4 is inferior to CA125, and this was tested using concordance and two-sided Fisher’s exact testing. McNemar’s test was used to assess the overall agreement of the two assays with the clinical status. RESULTS: A total of 129 patients with 272 separate clinical periods and 1739 events (serum samples) were evaluated. Using a 25% change in serum biomarker levels to indicate change in disease status, the accuracy and NPV determined for HE4 versus CA125 were 81.8% versus 82.6% ( p = 0.846) and 87.4% versus 89.7% ( p = 0.082), respectively. Concordance comparison of HE4 accuracy / CA125 accuracy was 0.990, indicating HE4 was not inferior to CA125 (McNemar’s test p-value = 0.522). Performing a velocity of change analysis, the accuracy and NPV determined for HE4 versus CA125 were 78.3% versus 78.6% ( p = 0.995) and 74.9% versus 76.3% ( p = 0.815), respectively. Concordance comparison of HE4 velocity accuracy / CA125 velocity accuracy was 0.996, again indicating HE4 was not inferior to CA125 (McNemar’s test p-value = 0.884). The combination of HE4 and CA125 velocity changes showed a similar accuracy of 81.3% ( p = 0.797 compared to HE4 and CA125 alone) and NPV of 81.1% ( p≥0.172 compared to HE4 and CA125 alone), and an increased sensitivity of 70.5% ( p≤0.070 compared to HE4 and CA125 alone). CONCLUSION: HE4 is equivalent to CA125 for monitoring of EOC patients. The combination of CA125 and HE4 velocities is superior to either marker alone.
Impact of Revenues from Oil and Non-Oil Sectors on the Economic Growth of Azerbaijan
Authors: Huseynli Nigar 
Published: September 2022

The main purpose of the study is to determine the relationship between the revenues obtained from the oil and non-oil sectors of Azerbaijan, which is a country dependent on the oil industry, and its economic growth. The fact that Azerbaijan is an oil-dominated country and a large part of its exports consist of oil may have caused us to think that the share of oil in the country's incomes will be higher. However, the fact that the country generally exports oil in crude form and imports it ready-made affects the final result. In this study, the share of the oil and non-oil sectors in the economic growth of the country over a 20-year period is determined. Another aim of the study is to reveal how the earnings from these two different sectors affect the employment level of the country. During the study, the logarithm of the variables was taken and included in the analysis in order to measure the strong relationship between the data. According to the results obtained, the development of these sectors affects the decrease in unemployment levels and has be a positive result between the realized economic growth and oil revenues and non-oil sector revenues.