bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aboveground biomass variation in working landscapes of southern Bahia, Brazil
Authors: Rocha¹ Janaine Isabela da Silva , Piotto Daniel 
Published: September 2022

Abstract

Native tropical forests have been increasingly modified in different land uses. Many of these lands have regrown into secondary forests and agroforestry systems. In this study, we investigate how different forest covers in a working landscape contribute to aboveground biomass in the southern region of Bahia, Brazil. We used Generalized Linear Models (GLM) to compare aboveground biomass in different forest covers, as follows: secondary forests of 10, 25 and 40 years old, mature forests and two different agroforestry systems (AFS): ‘cabruca’ and ‘conventional’. Our results showed that mature forests store the highest amount of biomass compared to other forest cover, followed by advanced stage secondary forests (40 years-old), AFS cabruca and AFS conventional. The lowest biomass was found in early-stage secondary forests (10 and 25 years-old). We emphasize here the importance of mature forests for carbon storage, in addition to maintaining various ecosystem services. Furthermore, we stress the importance of working landscapes that include agroforestry systems and secondary forests, as they provide timber and non-timber products, reduce the pressure on native forest resources, and contribute to the provision of ecosystem services such as carbon storage.
Combining pedological information with bioclimatic scenarios for evaluating the effect of climate change on the modelled distribution of forest species: case of study Apuleia leiocarpa
Authors: Bispo Diêgo Faustolo Alves , Beniaich Adnane , Freire Juliana Müller , Silva Ricardo Siqueira , Barroso Deborah Guerra 
Published: September 2022

Abstract
Sustainable wood production is one of the current challenges due to the increasing demand for wood worldwide. Despite, forest planting has proved to be a good solution; the high wood productivity can be achieved only under favorable bioclimatic conditions, which makes this study of great value for government policies. This study aimed to assess the impact of climate on the distribution of Apuleia leiocarpa in Rio de Janeiro and Minas Gerais, Brazil. The Species Distribution Models (SDMs) were performed using the MaxEnt model-based on-field survey of A. leiocarpa (n = 54). Pedological and bioclimatic data were used to identify suitable areas and climate change effects on the distribution of this species. Ours results have shown that the MaxEnt presented a good performance in modelling the distribution of the A. leiocarpa. The temperature was the main controlling variable of the distribution of this species. The pedological models overestimated of the suitable area. Despite that, the results provide useful information to be considered in the future in order to refine the selection of variables for a better characterization of the ecological niche. Regarding the projection of the future A. leiocarpa distribution, there was found an alarming scenario, which it must be taken into the consideration for the local authorities in order to establish a successful species-replanting program.
Thermodynamic Evaluation of Coshine Yukawa Potential (Cyp) for Some Diatomic Molecule Systems
Authors: Ekong Sylvester A. , Okorie Uduakobong S. , Ikot Akpan N. , Okon Ituen B. , Obagboye Lewis F. , Abdullah Hewa Y. , Sever Ramazan , Qadir Karwan W. 
Published: September 2022

Abstract
Within the framework of non-relativistic quantum mechanics, the bound state approximate solution of the SE is solved for the coshine Yukawa potential (CYP) using the Nikiforov–Uvarov (NU) method. By employing the Greene-Aldrich-type approximation scheme, we have obtained the explicit energy-eigenvalues and corresponding normalized eigen-functions in closed form for the newly proposed CYP for hydrogen-related diatomic molecules such as hydrogen dimer (H2), lithium hydride (LiH), scandium hydride (ScH) and hydrogen chloride (HCl). The thermodynamic properties are also evaluated including the vibrational partition function, vibrational mean energy, vibrational mean free energy, vibrational entropy and vibrational specific heat capacity. Presented also are some numerical results which show an indication of similar correlation of energies, owing to their ion-ion coupling with regards to similar atomic radii existing among the diatomic molecules.
The lesion responsible for the Alice in Wonderland syndrome with visual distortions is located in the right occipital lobe
Authors: Kobayashi Yuya , Tazawa Ko-ichi , Kondo Yasufumi , Yamamoto Kanji , Sekijima Yoshiki 
Published: September 2022

Abstract
Objective
Alice in Wonderland syndrome is extremely rare, occurring more often in young than elderly individuals. Symptoms typically include altered body image, size perception, and time perception. The pathophysiology and lesions responsible for Alice in Wonderland syndrome are unknown. In most cases, specific lesions cannot be identified with computed tomography or magnetic resonance imaging.
Methods
This was a single-center (Nagano Municipal Hospital, Japan), retrospective study that selected consecutive patients who presented with symptoms of Alice in Wonderland syndrome.
Results
Among the 4724 patients who presented to the emergency room with neurological symptoms, two were enrolled in this study. These patients had isolated cortical venous thrombosis in the right occipital area. Both experienced transient visual symptoms. A literature search indicated that Alice in Wonderland syndrome with visual distortions is associated with right occipital lobe lesions, supporting the present findings.
Conclusion
Lesions of the right occipital area can be responsible for visual distortions in Alice in Wonderland syndrome.
Evaluating haplotype associations for brown planthopper resistance in rice using the HAPLOANNOTATOR bioinformatics tool
Authors: Sawangkaew Non , Jamboonsri Watchareewan , Arikit Siwaret , Wanchana Samart , Toojinda Theerayut , Darwell Clive T. 
Published: September 2022

Abstract
Arthropod pests are a major contributor to rice production losses at a global scale and are predicted to increase in severity due to anthropogenic activity. It is generally recognised that an urgent requirement is to understand the genomic basis of crop-insect resistance to develop successful selective crop breeding programs capable of sustainably supporting future generations of human civilization. We evaluated phenotypic assay of rice resistance against its predominant arthropod pest, Nilaparvata lugens (brown planthopper; BPH) in Thailand. Using four geographically distinct BPH populations against a 227 strong rice accession panel, we identified eight key functional gene haplotypes (FGHs) in rice that statistically associate with high BPH resistance. Three of these were shown to associate with high resistance against all populations of examined BPH which likely represents two BPH biotypes. Finally, correlation analyses failed to detect strong signals of FGH pyramiding indicating that identified FGHs may be capable of conferring resistance independently. Our work relies on a newly developed bioinformatics tool, haploAnnotator, that provides graphical and statistical annotation of FGHs and should prove valuable to breeding research among all crops (not only rice) that possess a published genome.
On the Dynamical Instability of Monatomic Fluid Spheres in (N+1)-dimensional Spacetime
Authors: Feng Wei-Xiang 
Published: September 2022

Abstract
In this note, I derive the Chandrasekhar instability of a fluid sphere in (N + 1)-dimensional Schwarzschild-Tangherlini spacetime and take the homogeneous (uniform energy density) solution for illustration. Qualitatively, the effect of positive (negative) cosmological constant tends to destabilize (stabilize) the sphere. In the absence of cosmological constant, the privileged position of (3+1)-dimensional spacetime is manifest in its own right. As it is the marginal dimensionality in which a monatomic ideal fluid sphere is stable but not too stable to trigger the onset of gravitational collapse. Furthermore, it is the unique dimensionality that can accommodate stable hydrostatic equilibrium with positive cosmological constant. However, given the current cosmological constant observed no stable configuration can be larger than 1021 M⦿. On the other hand, in (2+1) dimensions it is too stable to collapse either in the context of Newtonian Gravity (NG) or Einstein's General Relativity (GR). In GR, the role of negative cosmological constant is crucial not only to guarantee fluid equilibrium (decreasing monotonicity of pressure) but also to have the Bañados-Teitelboim-Zanelli (BTZ) solution. Owing to the negativeness of the cosmological constant, there is no unstable configuration for a homogeneous fluid disk with mass 0 < M ≤ 0.5 to collapse into a naked singularity, which supports the Cosmic Censorship Conjecture. However, the relativistic instability can be triggered for a homogeneous disk with mass 0.5 < M ≲ 0.518 under causal limit, which implies that BTZ holes of mass MBTZ > 0 could emerge from collapsing fluid disks under proper conditions. The implicit assumptions and implications are also discussed.
Novel classification of petro-clival meningiomas (PCMs) in intradural anterior trans-petrosal approach
Authors: Bai Jie , Cheng Ye , Yang Wei , Wang Leiming , Li Xiaoran , Xiao Xinru 
Published: September 2022

Abstract
Objective
Surgical resection of petro-clival meningiomas (PCMs) is challenging. This study aimed to establish a novel classification of PCMs based on tumor extension during intradural anterior transpetrosal approach (ATPA) and establish optimal surgical strategies for PCMs based on the classification and review the clinical outcomes.
Methods
Between January 2013 and December 2019, 128 patients of with PCMs underwent surgery by the senior author (Xr.X.). According to tumour extension, we classified the 128 patients into five types (I-V) and introduced key technologies of intradural anterior transpetrosal approach (ATPA) in different types for the first time and achieve a supreme surgical technology. The clinical data, radiological findings, surgical treatment, complications, and outcomes of patients were then retrospectively analysed.
Results
There are 22 cases (17.2%) belonged to type I, 44 patients (34.4%) of type II, 25 patients (19.5%) of III, 29 patients (22.7%) of IV, 8 patients (6.3%) in type V. Tumours were gross totally removed (GTR, Simpson I and II) in 100 patients (78.1%), sub-totally (STR, Simpson III) in 20 patients (15.6%), partially (PR, Simpson IV) in 8 patients (6.3%). Progression or recurrence rates were 5% (5/100) in GTR, 22.3% (6/20) in STR ,62.5% (5/8, 1 died) in PR. According to Karnofsky Performance Scale and Glasgow Outcome Scale, 108 patients had good recovery (84.4%,108/128) and 115 had independent (89.8%,115/128) at the end of follow-up.
Conclusions
Totally resection of PCMs is challenging, with the help of our new classification with related key technologies. Increased tumour exposure, greater resection of tumour and nerve function protection can be achieved.
Effect of B7-H4 downregulation induced by Toxoplasma gondii infection on dysfunction of decidual macrophages contributes to adverse pregnancy outcomes
Authors: Cui Lijun , Wang Yu , Ren Liqin , Li Zhidan , Jiang Yuzhu , Wang Chao , Liu Xianbing , Ren Yushan , Hu Xuemei 
Published: September 2022

Abstract
Background: Toxoplasma gondii（T. gondii） infection during pregnancy can lead to fetal defect or congenital complications. The inhibitory molecule B7-H4 expressed on decidual macrophage (dMφ) exerted important role in maternal-fetal tolerance. However, the effect of B7-H4 on the function of dMφ during T. gondii infection remains unclear.
Methods: In the present study, the change of B7-H4 expression on dMφ after T. gondii infection were explored in vivo and in vitro. B7-H4-/- pregnant mice and purified primary human dMφ treated by B7-H4 neutralizing antibody were used to explore the role of B7-H4 signaling on regulating the membrane molecules, arginine metabolic enzymes synthesis, and cytokines production of dMφ with T. gondii infection. Also adoptive transfer of dMφ from WT pregnant mice or B7-H4-/- pregnant mice to infected B7-H4-/- pregnant mice were used to examine the effect of B7-H4 on adverse pregnancy outcomes induced by T. gondii infection.
Results: Our results illustrated that B7-H4-/- pregnant mice infected by T. gondii displayed poorer pregnancy outcomes than those of the wild-type counterparts. B7-H4 expression on dMφ significantly decreased after T. gondii infection, which further resulted in the polarization of dMφ from M2 toward M1 phenotype by changing the expression of membrane molecules (CD80, CD86, CD163, CD206), arginine metabolic enzymes (Arg-1, iNOS) synthesis, and cytokines (IL-10, TNF-α) production. Also, we found that the B7-H4 down-regulation after T. gondii infection increased iNOS and TNF-α expression through JAK2/STAT1 signaling pathway. Besides, adoptive transfer of dMφ from WT pregnant mice donor rather than B7-H4-/- pregnant mice donor could improve adverse pregnancy outcomes induced by T. gondii infection.
Conclusions: The results demonstrated that the downregulation of B7-H4 induced by T. gondii infection leaded to the dysfunction of decidual macrophages and contributed to abnormal pregnancy outcomes. Moreover, adoptive transfer of B7-H4+dMφ could improve adverse pregnancy outcomes induced by T. gondii infection.
Using Multi-index Model to Assess the Risk From Flash Flood: a Geospatial Approach on Sunamganj Haor (Wetland) Region, Bangladesh
Authors: Saha Gourab , Kabir Md. Najmul , Khandaker Afrin 
Published: September 2022

Abstract
Heavy downpours in Meghalaya and Assam regions are causing flash floods in Bangladesh's northeastern Haor region at regular intervals. As high volume of water enters into the Surma river through the downstream river network, the Haor region faces heavy damage almost every year. The major focus of the study was to assess the risk of flash floods in the greater Sylhet region. Literature review of past flood scenarios have shown that Sunamganj District directly faces the wrath of flash floods each year and witnesses tremendous damage. A geospatial multi-index model was developed which considered four major indices (hazard, exposure, sensitivity, and resilience) for this risk assessment. The model systematically accounted for various flood risk indicators related to the economic, social, and physical environment of the Sunamganj District. Geostatistical methods were used to calculate the risk from the indicators and Principal Component Analysis (PCA) was used for composite analysis. The result showed that the high- and very high-risk zones occupied almost 40% (~ 1452.51 Km2), while the very low- and low-risk zones covered about 45% (~ 1554.66 Km2) of the Sunamganj District. Based on the risk rank, Dharampasha upazila had high percentage (~ 60%) which followed by Sulla, Derai, Jamalganj, Daksin Sunamganj, and Tahirpur upazilas respectively. The proposed methods will help the researchers to identify the causes of flash floods and the results will be helpful for policymakers and developers to take steps for flash flood risks reduction.
Examination of the Effectiveness of Local Therapy for Oligo-recurrence of Epidermal Growth Factor Receptor-Mutated Non-Small Cell Lung Cancer
Authors: Sonoda Dai , Kondo Yasuto , Maruyama Raito , Hayashi Shoko , Naito Masahito , Mikubo Masashi , Matsui Yoshio , Shiomi Kazu , Satoh Yukitoshi 
Published: September 2022

Abstract
Purpose
The effectiveness of local therapy was recently reported in patients with non-small cell lung cancer (NSCLC) oligo-recurrence, a metachronous recurrence with a limited number of recurrences. Conversely, systemic therapy for NSCLC has made remarkable progress with the advent of molecular targeted therapy. In particular, epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) arevery effective in the treatment of EGFR-mutated NSCLC. This study aimed to evaluate the effectiveness of radical local therapy for oligo-recurrence in EGFR-mutated NSCLC.
Methods
Between 2004 and 2014, 811 patients underwent complete resection for NSCLC at Kitasato University Hospital, and 244 of these patients developed recurrence. Oligo-recurrence was defined as the presence of two or fewer recurrent lesions, and 34 patients presented with EGFR-mutated oligo-recurrence. We retrospectively examined and compared the effects of EGFR-TKIs with those of radical local therapy in patients with oligo-recurrent EGFR-mutated NSCLC.
Results
The five-year post-recurrence survival (PRS) rates of patients with EGFR-mutated oligo-recurrence who received radical local therapy (n = 23) and those who did not (n = 11) were 59.4% and 45.5%, respectively (P = 0.777). Multivariate analysis revealed no favorable prognostic factors associated with prolonged PRS, and radical local therapies did not improve PRS in patients with oligo-recurrence (P = 0.551).
Conclusion
Radical local therapy did not affect PRS in patients with oligo-recurrent EGFR-mutated NSCLC. Thus, even in cases of oligo-recurrence, the administration of local therapy in patients with EGFR-mutated NSCLC must be carefully considered.
Sonochemistry in organic synthesis: A convenient method for the preparation of halo-bicyclic molecules with keten addition reaction and biological properties of Dimethyl 7,7-dichloro-8-oxabicyclo[4.2.0]oct-3-ene-3,4- dicarboxylate
Authors: Sezen Hazal , Kuş Nermin Şimşek , Özdemir Sadin , Tollu Gülşah 
Published: September 2022

Abstract
A convenient method for the preparation of halo-bicyclic molecules likely to show biological activity, from keten addition reaction with dimethyl cyclohexa-1,4-diene-1,2-dicarboxylate (3) and dichloroketene, respectively, under ultrasound irradiation, is reported. First, 1,4-diene 3 had been synthesized with Diels-Alder addition, and then the ketene addition reaction was carried out. Ultrasonic and non-ultrasonic conditions in the ketene addition reaction were investigated. Then, lactones (8 and 9) were obtained from ketene adducts. The structures of the molecules were illuminated by IR, and NMR spectroscopy techniques, especially Cosy spectroscopy. The test compounds improved antioxidant ability from 9.48% to 69.29% at concentration rates of 12.5-200 mg/L. The newly synthesized dichloro lactone 8 showed good antibacterial activity against gram-negative and –positive bacteria and also, antifungal activity. The antibiofilm activity of dichloro lactone 8 investigated and it showed 99.92 and 99.14% biofilm inhibiton activity againts Staphylococcus aureus and Pseudomonas aeruginosa, respectively at concentration of 250 mg/L. Moreover, it was displayed 100% Escherichia coli viability inhibition at concentrations of 125 and 250 mg/L.
ncRNAs-mediated TIMELESS overexpression in lung adenocarcinoma correlates with reduced tumor immune cell infiltration and poor prognosis
Authors: Gao Xinliang , Tang Mingbo , Tian Suyan , Li Jialin , Liu Wei , Hua Shucheng , Wei Shixiong 
Published: September 2022

Abstract
Background
Lung adenocarcinoma (LUAD) has a poor prognosis. Circadian genes such as TIMELESS have been associated with several pathologies, including cancer. The expression of TIMELESS and the relationship between TIMELESS, infiltration of tumors and prognosis in LUAD requires further investigation.
Methods
In this study, we investigated the expression of TIMELESS and its association with survival across several types of human cancer using data from The Cancer Genome Atlas (TCGA) and the Genotype-Tissue Expression Program. Noncoding RNAs (ncRNAs) regulating overexpression of TIMELESS in LUAD were explored with expression, correlation, and survival analyses. Immune cell infiltration and biomarkers were analyzed between different TIMELESS expression levels. The relationship between TIMELESS expression and immunophenoscores, which were used to predict response to immunotherapy, was evaluated.
Results
TIMELESS was identified as a potential oncogene in LUAD. NcRNA analysis showed MIR4435-2HG/hsa-miR-1-3p may interact with TIMELESS in a competitive endogenous RNA network in LUAD tumor tissues. Most immune cells were significantly decreased in TCGA LUAD tumor tissues with high TIMELESS expression except for CD4 + T cells and Th2 cells. TIMELESS expression in LUAD tumor tissues was significantly negatively correlated with neutrophil biomarkers, dendritic cell biomarkers (HLA-DPB1, HLA-DQB1, HLA-DRA, HLA-DPA1, CD1C) and an immunophenoscore that predicted outcomes associated with the use of immune checkpoint inhibitors.
Conclusions
These findings imply that ncRNAs-mediated TIMELESS overexpression in LUAD tumor tissues correlated with poor prognosis, reduced immune cell infiltration in the tumor microenvironment, and poor response to immune checkpoint inhibitors.
Shared rules between planetary orbits displayed by multi-planet systems and their function
Authors: Ma Yong , Wen Xiumei 
Published: September 2022

AbstractTo better understand orbital relationships, we calculated the exoplanetary observation data of all multi-planet systems with the method of orbital ratio parameter analysis. The calculations display the orbital relationships between all exoplanets of each multi-planet system in a clearer quantification way, including the exoplanets of mean motion resonances (MMRs). By statistics and comparisons, we found more orbital features beyond MMRs and summarized them into the shared rules between planetary orbits. Meanwhile, we derived corresponding equations and principles, based on which we classified the 96 four-and-more-planet extrasolar systems observed. According to Criterion (N-B), 83 are the systems with the shared rules. By analysis, we proposed migratory and absent exoplanets, and calculated their orbits. We also summed up the main reasons why exoplanets migrate or are absent, which cause large deviation rates. The discovery of the shared rules provides a different way to study the completeness and evolution of multi-planet systems.