bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reactivating Positive Personality Traits During Sleep Impacts Self-Evaluative Memories
Authors: Yao Ziqing , Xia Tao , Zhang Zhiguo , Lin Xuanyi , Qin Pengmin , Ma Yina , Hu Xiaoqing 
Published: December 2022

Abstract
People tend to view themselves through rose-tinted glasses, as evidenced by preferential recall of positive personality traits. We asked whether reactivating positive personality traits during sleep could enhance peoples’ positive self-evaluative memories. After a baseline self-referential encoding task in which participants endorsed positive and negative traits as self-descriptive, participants were trained to give timely responses to positive traits in a cue-approach training (CAT) task. Once participants had entered slow-wave sleep during a subsequent nap, half of the trained positive traits were unobtrusively re-played to them to promote consolidation (targeted memory reactivation, TMR). Participants completed free-recall tasks about self-descriptive traits to measure their self-evaluative memories. Our findings revealed that TMR prioritized the recall of positive traits that were strongly memorized before sleep, while impairing the recall of intermediate traits. The results suggest pre-TMR self-evaluative memory strength modulated the TMR benefits. Sleep EEG analyses revealed that compared with weak/intermediate/control traits, re-playing strongly memorized traits during sleep elicited greater sigma power changes, which likely reflect preferential memory reactivation. Our results demonstrate the potential implication of wakeful cue-approach training and sleep-based memory reactivation in strengthening positive self-evaluative memories.
Monte Carlo simulations of synchrotron X-ray dose effects on root growth during in-vivo tomographic imaging
Authors: Moraes Isabela C. , Hesterberg Dean , Neto Fernando A. Bacchim , Archilha Nathaly L. , Pérez Carlos A. , Araújo Maria Victória A. , Ferreira Talita R. 
Published: December 2022

Abstract
Synchrotron X-ray computed tomography (XCT) has been increasingly applied to study the in-vivo dynamics of root growth and rhizosphere processes. However, minimizing radiation-induced damage to root growth warrants further investigation. Our objective was to develop a robust approach for modeling and evaluating ways to reduce synchrotron X-ray dose effects on root growth during in-vivo imaging. Wheat roots growing in soil were exposed to X-rays during XCT experiments resolved in space (3-D) plus time (4-D). The dose rate and cumulative absorbed dose in roots were modelled with the Monte Carlo code FLUKA considering different experimental conditions using polychromatic and quasi-monochromatic X-ray beam configurations. The most impactful factors affecting damage to roots were incident X-ray energy spectrum, stored current in the accelerator machine, position of the root in the soil, and possibly the number of exposures during the 4-D XCT experiments. Our results imply that radiation dose during in-vivo imaging of plant roots can be diminished by using monochromatic radiation at the highest energy suitable for a given sample thickness and field of view, and by controlling the rotation axis of off-centered roots to increase radiation protection by soil.
Estimation of Process Performance Index for Two-Parameter Exponential Distribution with Measurement Error
Authors: Li Yi , Chiang Jyun-You , Bai Yajie , Chaia Kuang-Cheng 
Published: December 2022

Abstract
Since measurement errors are inevitable in practice, and they are not considered in the existing process performance index, we propose an estimation method of process performance index for two-parameter exponential distribution with measurement errors. In this paper, the relationship between the unobservable actual value and measurement value is considered as an additive measurement error model. The maximum likelihood estimation method is considered to obtain the unknown parameters. In addition, we also use the Bootstrap method to construct confidence intervals of process performance index. The performance of the proposed estimation is investigated in terms of bias, mean square error (MSE) and average interval length. Simulation results show that the proposed estimator outperforms the estimates that do not account for measurement error. Finally, an example of the mileage data of the military personnel carrier is given to illustrate the implementation of the proposed estimation method.
Visceral Adiposity：A Potential Marker for Mortality Risk in Heart Failure with Preserved Ejection Fraction?
Authors: Zhao Jin , Zhang Xiaofang , Xiao Jin , Yi Hanwen , Deng Xiangliang , Sun Min , Bai Hongmei , Tan Xiaowei , Liu Zhiqiang , Wen Xuesong , Wang Xi , Ge Ping , Zhang Dongying , Gao Lei 
Published: December 2022

Abstract
Background

Recent research reports that regional adiposity, notably epicardial and visceral fat, may serve a pivotal pathophysiologic role in heart failure with preserved ejection fraction (HFpEF). We aimed to describe the role of regional adiposity in predicting all-cause death in patients with HFpEF.

Methods

This was a prospective cohort study in patients with HFpEF, and the primary outcome of this study was all-cause mortality. Visceral fat area (VFA) was measured through the multifrequency bioelectrical impedance analyzer (BIA). The thickness of epicardial adipose tissue (EAT) and pericardial adipose tissue (PAT) was measured by echocardiography. Cox regression analysis was used to evaluate the predicted effect of the potential risk factors. Test for interaction was used to estimate whether the prognostic value of VFA was affected by subgroups of potential risk confounders.

Results

A total of 172 patients with an average age of 72 years were analyzed, of which 59.9% (n = 103) were females. 66% were hypertensive and 40% had atrial fibrillation (AF). The best cutoff value of VFA for all-cause death was 148.3cm2. The all-cause mortality rate in the VFA ≥ 148.3 cm2 group was significantly higher than in the VFA < 148.3 cm2 group. Patients with higher VFA were older, with higher body mass index (BMI), and more frequently with pre-existing hypertension and atrial fibrillation. Age, smoking, BMI, H2PEFF score, and VFA were significantly associated with higher mortality in HFpEF by univariable Cox analysis. However, PAT thickness, EAT thickness, waist/hip ratio, body fat mass, and abdominal obesity were not effective predictors of HFpEF outcomes. After adjusting for cofounders of other underlining risk factors, VFA could independently predict all-cause mortality in HFpEF. In addition, results were broadly consistent in participants with different baseline characteristics.

Conclusions

VFA may be a useful prognostic risk factor for all-cause mortality in patients with HFpEF.

Trial registration

NCT05496439 (08/10/2022), retrospectively registered.
Low TFPI2 expression is associated with poor prognosis and defective immune cell infiltration in breast cancer disease
Authors: Zhu Cheng , Dai Ying , Zhang Yanyan , Wang Hua , Hu Xiaolei 
Published: December 2022

Abstract
Background
Breast cancer is the leading cause of death in female cancer population worldwide. The mainstay treatment for breast cancer includes chemotherapy, targeted therapy, endocrine therapy and immunotherapy. Tissue factor pathway inhibitor 2 (TFPI2) plays an important role in balancing the activity of various enzymes in the human environment. However, the correlation of TFPI2 to the prognosis and the immune infiltration in breast cancer has not been reported.
Methods
We firstly analyzed the expression level of TFPI2 via high-throughput sequencing, clinical sample detection and cancer genome profiling (TCGA).
Results
TFPI2 expression was significantly downregulated in different subtypes of breast cancer samples. Downregulation of TFPI2 expression was associated with multiple clinical features and poor prognosis. In the tumor microenvironment (TME), TFPI2 is positively correlated with immune cells and immune modulators (chemokines, receptors, immunostimulants, immunosuppressants and MHC). With TFPI2 upregulation, immune and stromal components significantly increased.
Conclusion
This is the first comprehensive study to reveal that TFPI2 may serve as a novel prognostic biomarker associated with tumor immune infiltration and provide a potential therapeutic target in breast cancer.
User Acceptance of Healthcare Robots Through Extended UTAUT2: A Mixed Method Approach
Authors: Lorella Cannavacciuolo , Rippa Pierluigi , Caputo Sergio 
Published: December 2022

Abstract
Background
Technological change is reshaping the economic, social and cultural scenarios in which we live. In the health care sector, the response to this change is observed with the advent of eHealth, that employ technologies to support both the healthcare professionals and managers and the patient in his or her care journey. The utilization in practice of these technologies moves the attention to the users. Focusing on the patient side, this study proposes a model aimed at understanding the intention to use the eHealth technology.
Methods
A model based on UTAUT2 has been tested using a mixed approach combining Partial Leas Squares (PLS) and crisp-set Qualitative Comparative Analysis (csQCA) with the aim of identifying recipes fostering eHealth adoption. Data was collected through an online survey on a sample of 208 respondents. PLS and csQCA helped identify causal combinations of variables that lead the PLS and csQCA are complementary analytical approaches providing novel and more reliable information.
Results
The PLS analysis show that the model strongly predicted the intention to use healthcare robot (R-square=0.759). According to the model's path coefficients, Trust in Technology and Performance Expectation are the most powerful significant predictors of intentions to use the robot (TRU: 0.259, ρ<0.001; PE: 0.236, ρ<0.01). Hedonic Motivation (0.180, ρ <0.01) and Social Influence (0.126, ρ <0.05) predicted intention to use positively, while Technology Anxiety (-0.177, ρ <0.001) predicted intention to use negatively. The csQCA reveals four configurations, including the PLS identified factors. The results indicate that several conditions that were not significant in PLS are sufficient when combined with other conditions.
Conclusions
This study emphasizes the importance of adopting an integrated approach centered on performance expectancy, trust in technology, social influence, and hedonic motivation while paying attention to anxiety when using technologies. Our findings could support the practitioners in activating actions oriented to enhance the intention to use of a specific eHealth technology, keeping in account not only the technological aspects but all the variables that affect its utilization.
Increasing importance of crustose coralline algae to coral reef carbonate production under ongoing climate change
Authors: Cornwall Christopher , Carlot Jérémy , Branson Oscar , Courtney Travis , Harvey Ben , Perry Chris T. , Andersson Andreas , Diaz-Pulido Guillermo , Johnson Maggie , Kennedy Emma , Mallela Jennie , McCoy Sophie , Nugues Maggy , Quinter Evan , Krieger Erik , Ross Claire , Ryan Emma , Saderne Vincent , Comeau Steeve 
Published: December 2022

AbstractUnderstanding the drivers of net coral reef calcium carbonate production is increasingly important as ocean warming, acidification, and other anthropogenic stressors threaten the maintenance of coral reef structures and the services these ecosystems provide. Despite intense research effort on coral reef calcium carbonate production, the inclusion of a key reef forming/accreting calcifying group, the crustose coralline algae (CCA), remains challenging both from a theoretical and practical standpoint. While corals are typically the primary reef builders of today, ongoing declines in coral cover due to a range of environmental perturbations will likely increase the relative importance of CCA and other non-scleractinian calcifying taxa to coral reef carbonate production. Here, we demonstrate that CCA are important carbonate producers that, under certain conditions, can match or even exceed the contribution of corals to coral reef carbonate production. Despite their importance, CCA are often inaccurately recorded in benthic surveys or even entirely missing from coral reef carbonate budgets. We outline several recommendations to improve the inclusion of CCA into such carbonate budgets under the ongoing climate crisis.
Defensive eversible organ in swallowtail larvae: morphology, structure, chemistry and defensive efficacy
Authors: Palma-Onetto Valeria , Bergmann Jan , González-Teuber Marcia 
Published: December 2022

Abstract
Chemical secretions are one of the main defensive mechanisms in insects. The osmeterium is a unique organ in larvae of Papilionidae (Lepidoptera), which is everted upon disturbance, secreting odoriferous volatiles. Here, using larvae of the specialized butterfly Battus polydamas archidamas (Papilionidae: Troidini), we aimed to understand the mode of action of the osmeterium, the chemical composition of the secretion, the origin of the secreted volatiles, as well as its defensive efficacy against a natural predator. We described the morphology, ultramorphology, structure, ultrastructure, and chemistry of this defensive organ. Additionally, behavioral assays of the osmeterial secretion against a predator were developed. We showed that the osmeterium is composed of tubular arms (made up by epidermal cells) and of two ellipsoid glands, which possess a secretory function. The eversion and retraction of the osmeterium are dependent on the internal pressure generated by the hemolymph, and by longitudinal muscles that connect the abdomen with the apex of the osmeterium. Germacrene A was the main compound present in the secretion. Minor amounts of monoterpenes (sabinene and ß-pinene) and sesquiterpenes ((E)-β-caryophyllene, selina-3,7(11)-diene, and other not identified compounds) were also identified. Only sesquiterpenes (with the exception of ((E)-β-caryophyllene) are likely to be synthesized in the osmeterium-associated glands. Furthermore, the osmeterial secretion showed an effective repellent effect on predators. Our results suggest that the osmeterium, besides serving as an aposematic warning for enemies, is an efficient chemical defense, with its own synthesis of irritant volatiles.
Anti-vibriosis bioactive molecules from Arctic Penicillium sp. Z2230
Authors: Guo Jiacheng , Yang Jin , Wang Pei , Guo Bo , Li Huifang , Zhang Di , An Faliang , Gao Song 
Published: December 2022

Abstract
Vibrio species (Vibrio sp.) is a class of gram-negative aquatic bacteria that causes vibriosis in aquaculture and leads to big economic losses. Antibiotics have been used to control vibriosis, but concerns on antibiotic resistance keep raising. Natural products are important sources of drug lead compounds that provide potential antibiotic alternatives. In this study, seven compounds were isolated from the Arctic endophytic fungus Penicillium sp. Z2230 and determined for the structures. Among these seven compounds, compounds 3, 4, and 5 showed anti-Vibrio activity, and the antibacterial mechanisms were explored by molecular docking. The results suggested that the anti-Vibrio activities could come from the inhibition of bacterial peptide deformylase (PDF). The data indicate that these Penicillium-derived compounds are potential lead molecules for developing novel anti-Vibrio agents, and PDF is a promising antibacterial target. This study expands the bioactive diversity of polar endophytic fungi by showing a good example in which the secondary metabolites of a polar microbe are a good source of natural medicine.
A modified technique to repair severe Ebstein’s anomaly: a monocusp with autologous pericardium
Authors: Qiu Zhi-Huang , Wu Qing-Song , chen Liang-Wan 
Published: December 2022

Abstract
We describe a modified technique for repairing severe Ebstein’s anomalies. The anterior and posterior leaflets were detached from the right ventricle (RV), followed by longitudinal plication of the lateral posterior wall to reduce both the enlarged true tricuspid annulus and the atrialized RV. The separated anterior and posterior leaflets, as well as autologous pericardium of a corresponding size, were sutured on the true tricuspid annulus.The pericardial patch was fixed to the papillary muscle with an artificial tendon. Finally, we closed the atrial septal defect or the patent foramen ovale. Our initial application showed that this technique could effectively repair the tricuspid valve and achieve satisfactory right ventricular function.
Identification of a putative novel cholivirus in the transcriptome of Gymnema sylvestre R. Br
Authors: Sidharthan V. Kavi , Vanamala Gayatri , Rajeswari V , Baranwal V. K. 
Published: December 2022

Abstract
Gymnema sylvestre is a tropical climber species that is widely used in traditional medicine since ages. In the present study, the transcriptome datasets of G. sylvestre available in public domain were screened for the presence of novel plant viral sequences and a putative novel virus tentatively named as Gymnema sylvestre virus 1 (GysV1) was identified. Coding-complete genome segments of GysV1 that are 6.35 kb (RNA1) and 3.98 kb (RNA2) long possessed a single large open reading frame coding for a polyprotein. BLASTp, sequence identity and phylogenetic analyses revealed the relatedness of GysV1 to the members of the subgenus Cholivirus (genus Sadwavirus; family Secoviridae; order Picornavirales). Based on the species demarcation criteria of the family Secoviridae, GysV1 can be regarded as a new cholivirus member.
Large-Scale Climate Drivers of Interannual to Multidecadal Variability in Rainfall Occurrence during Indian Summer Monsoon
Authors: Pal Lalit , Ojha Chandra Shekhar Prasad 
Published: December 2022

AbstractRainfall occurrence (or rainy days) during the Indian summer monsoon (ISM) exhibits a significant decline over the last century, that is considerably more widespread than the decline observed in rainfall magnitude. Here, we investigate the teleconnections of monsoon rainfall occurrence in India with prominent large-scale climate systems to examine their role in the observed widespread decline. Study results reveal strong interannual (5–12 years) periodicities in rainfall occurrence over central and western parts of north India, whereas multidecadal (30–40 years) periodicities are found dominant over northwest Himalayas, northeast India and parts of south India. El Niño-Southern Oscillations (ENSO) dominates the interannual variability and exhibits strong negative linkage with rainfall occurrence over the entire country except for northeast and parts of south India. The influence of Indian Ocean Dipole (IOD) and Pacific Decadal Oscillations (PDO) is mainly observed as modulations to ENSO’s linkage with rainfall occurrence at interannual and decadal timescales, respectively. Co-occurrence of strong (negative or positive) IOD results in supressed influence of ENSO, whereas warm (cold) PDO is associated with suppressed (enhanced) ENSO impact on rainfall occurrence. After 1950s, PDO’s linkage with rainfall occurrence has strengthened over northeast, western Himalayas, and peninsular south India, that is responsible for the observed dominance of multidecadal periodicities. IOD’s linkage with rainfall occurrence has also strengthened after 1970s over northwest, west central and parts of peninsular India leading to strong positive relationship in recent years. Further investigation suggests that the observed decline in rainfall occurrence is attributable to the shorter and less frequent La Niña events and stronger positive IOD events in the warming climate. The study findings would essentially benefit in accurate predictions and long-term projections of monsoon rainfall occurrence to facilitate planning and policy making.
The Homology and Homotopy Groups of Hermitian Symmetric Spaces
Authors: DAVIS SIMON 
Published: December 2022

Abstract
A method for computing homotopy groups of SU(3) and G2 from the cross sectioning of exact sequences for the fibrations SU(2) → SU(3) → S5 and SU(3) → G2 → S6, and the localizations at odd primes, is developed. The homol-ogy and homotopy groups of hermitian symmetric spaces are derived through exact sequences. It is found that the homotopy groups of the classical and exceptional coset manifolds with simple stability groups may be deduced generally from the known homotopy groups of unitary groups and spheres, When the stability group consists of a product of simple groups, the homology groups will receive an extra component by the Künneth formula. It follows that the second homology group and the first Chern characteristic class of the two exceptional Hermitian symmetric spaces will be nonvanishing. Bott periodicity of the stable homotopy groups of the classical Hermitian symmetric spaces is proven through the exact sequences for the cosets of orthogonal, unitary and symplectic groups. Homotopy groups of EIII = E6 / (Spin(10)×U (1))/Z4 , EVII = E7 / (E6×U (1))/Z3, EIX = E8 / (E7×SU(2))/Z2 and the boundaries of noncompact Hermtian symmetic spaces in plance convex domains are computed. A geometrical representation for universal Teichmüller space as the limit of a sequence of Hermitian symmetric spaces is given, and the Diff(S1)/S1 theory, formulated through vector bundles on this manifold is an integrable system.
MSC: 55E05, 55E40, 57F10, 57F15
Potential Impacts of Land Use Changes and Climate Variations on Flows in a Basin in Northeastern Brazil
Authors: Sousa Lucas Farias , Ferraz Lorena Lima , Santos Carlos Amilton Silva , Rocha Felizardo Adenilson , Jesus Raildo Mota 
Published: December 2022

Abstract
The present study sought to evaluate the sensitivity of several ecologically relevant flow parameters to land use changes and climate change. The study was carried out in the Cachoeira River Basin located in the Atlantic Forest biome with predominately agricultural activities in its drainage area, in the state of Bahia, Brazil. To achieve the proposed objective, the Soil and Water Assessment Tool (SWAT) model was used to calibrate and validate the historical flow series from 1985 to 2015, create the simulation scenarios, and subsequently evaluate the hydrological changes in the different scenarios proposed through the 19 indices in the Indicators of Hydrologic Alteration (IHA) software. The results reveal that the maximum flows of 30 and 90 days, as well as the number of reversals, will be the most affected by future climate conditions. These significant changes indicate that the flows are mainly linked to changes in precipitation patterns in the basin. Thus, the negative medium and long-term trend of these flows can alter the availability of water in the basin and affect not only aquatic life but also the socio-economic development of the basin, with consequences for the water supply to cities and riverside populations that use its tributaries as a source of food, income, and leisure.