bluuebunny/crossref_metadata_2025_split huggingface dataset:
Treatment completion among justice-involved youth engaged in behavioral health treatment studies in the United States: A systematic review and meta-analysis
Authors: Johnson-Kwochka Annalee , Salgado Eduardo F. , Pederson Casey A. , Aalsma Matthew C. , Salyers Michelle P. 
Published: June 2022

Abstract
Justice-involved youth (JIY) have high rates of behavioral health disorders, but few can access, much less complete, treatment in the community. Behavioral health treatment completion among JIY is poorly understood, even within treatment studies. Measurement, reporting, and rates of treatment completion vary across studies. This systematic review and meta-analysis synthesizes the literature on rates of treatment completion among JIY enrolled in research studies and identifies potential moderators. After systematically searching 6 electronic databases, data from 13 studies of 20 individual treatment groups were abstracted and coded. A meta-analysis examined individual prevalence estimates of treatment completion in research studies as well as moderator analyses. Prevalence effect sizes revealed high rates of treatment completion (pr = 82.6). However, analysis suggests a high likelihood that publication bias affected the results. Treatment groups that utilized family- or group-based treatment (pr = 87.8) were associated with higher rates of treatment completion compared to treatment groups utilizing individual treatment (pr = 61.1). Findings suggest that it is possible to achieve high rates of treatment completion for JIY, particularly within the context of family- and group-based interventions. However, these findings are limited by concerns about reporting of treatment completion and publication bias.
Harnessing robot experimentation to optimize the regulatory framing of emerging robot technologies
Authors: Calleja Carlos , Drukarch Hadassah , Fosch-Villaronga Eduard 
Published: June 2022

Abstract
From exoskeletons to lightweight robotic suits, wearable robots are changing dynamically and rapidly, challenging the timeliness of laws and regulatory standards that were not prepared for robots that would help wheelchair users walk again. In this context, equipping regulators with technical knowledge on technologies could solve information asymmetries among developers and policymakers and avoid the problem of regulatory disconnection. This article introduces pushing robot development for lawmaking (PROPELLING), an financial support to third parties from the Horizon 2020 EUROBENCH project that explores how robot testing facilities could generate policy-relevant knowledge and support optimized regulations for robot technologies. With ISO 13482:2014 as a case study, PROPELLING investigates how robot testbeds could be used as data generators to improve the regulation for lower-limb exoskeletons. Specifically, the article discusses how robot testbeds could help regulators tackle hazards like fear of falling, instability in collisions, or define the safe scenarios for avoiding any adverse consequences generated by abrupt protective stops. The article’s central point is that testbeds offer a promising setting to bring policymakers closer to research and development to make policies more attuned to societal needs. In this way, these approximations can be harnessed to unravel an optimal regulatory framework for emerging technologies, such as robots and artificial intelligence, based on science and evidence.
Expansin-mediated developmental and adaptive responses: A matter of cell wall biomechanics?
Authors: Samalova Marketa , Gahurova Evelina , Hejatko Jan 
Published: June 2022

Abstract
Biomechanical properties of the cell wall (CW) are important for many developmental and adaptive responses in plants. Expansins were shown to mediate pH-dependent CW enlargement via a process called CW loosening. Here, we provide a brief overview of expansin occurrence in plant and non-plant species, their structure and mode of action including the role of hormone-regulated CW acidification in the control of expansin activity. We depict the historical as well as recent CW models, discuss the role of expansins in the CW biomechanics and address the developmental importance of expansin-regulated CW loosening in cell elongation and new primordia formation. We summarise the data published so far on the role of expansins in the abiotic stress response as well as the rather scarce evidence and hypotheses on the possible mechanisms underlying expansin-mediated abiotic stress resistance. Finally, we wrap it up by highlighting possible future directions in expansin research.
Turgor pressure change in stomatal guard cells arises from interactions between water influx and mechanical responses of their cell walls
Authors: Yi Hojae , Chen Yintong , Anderson Charles T. 
Published: June 2022

Abstract
The ability of plants to absorb CO2 for photosynthesis and transport water from root to shoot depends on the reversible swelling of guard cells that open stomatal pores in the epidermis. Despite decades of experimental and theoretical work, the biomechanical drivers of stomatal opening and closure are still not clearly defined. We combined mechanical principles with a growing body of knowledge concerning water flux across the plant cell membrane and the biomechanical properties of plant cell walls to quantitatively test the long-standing hypothesis that increasing turgor pressure resulting from water uptake drives guard cell expansion during stomatal opening. To test the alternative hypothesis that water influx is the main motive force underlying guard cell expansion, we developed a system dynamics model accounting for water influx. This approach connects stomatal kinetics to whole plant physiology by including values for water flux arising from water status in the plant .
String diagram rewrite theory III: Confluence with and without Frobenius
Authors: Bonchi Filippo , Gadducci Fabio , Kissinger Aleks , Sobociński Paweł , Zanasi Fabio 
Published: June 2022

AbstractIn this paper, we address the problem of proving confluence for string diagram rewriting, which was previously shown to be characterised combinatorially as double-pushout rewriting with interfaces (DPOI) on (labelled) hypergraphs. For standard DPO rewriting without interfaces, confluence for terminating rewriting systems is, in general, undecidable. Nevertheless, we show here that confluence for DPOI, and hence string diagram rewriting, is decidable. We apply this result to give effective procedures for deciding local confluence of symmetric monoidal theories with and without Frobenius structure by critical pair analysis. For the latter, we introduce the new notion of path joinability for critical pairs, which enables finitely many joins of a critical pair to be lifted to an arbitrary context in spite of the strong non-local constraints placed on rewriting in a generic symmetric monoidal theory.
Human‐Climate Coupled Changes in Vegetation Community Complexity of China Since 1980s
Authors: Su Yanjun , Guo Qinghua , Guan Hongcan , Hu Tianyu , Jin Shichao , Wang Zhiheng , Liu Lingli , Jiang Lin , Guo Ke , Xie Zongqiang , An Shazhou , Chen Xuelin , Hao Zhanqing , Hu Yuanman , Huang Yongmei , Jiang Mingxi , Li Jiaxiang , Li Zhenji , Li Xiankun , Li Xiaowei , Liang Cunzhu , Liu Renlin , Liu Qing , Ni Hongwei , Peng Shaolin , Shen Zehao , Tang Zhiyao , Tian Xingjun , Wang Xihua , Wang Renqing , Xie Yingzhong , Xu Xiaoniu , Yang Xiaobo , Yang Yongchuan , Yu Lifei , Yue Ming , Zhang Feng , Chen Jun , Ma Keping 
Published: June 2022

AbstractVegetation community complexity is a critical factor influencing terrestrial ecosystem stability. China, the country leading the world in vegetation greening resulting from human activities, has experienced dramatic changes in vegetation community composition during the past 30 years. However, how China's vegetation community complexity varies spatially and temporally remains unclear. Here, we examined the spatial pattern of China's vegetation community complexity and its temporal changes from the 1980s to 2015 using two vegetation maps of China as well as more than half a million field samples. Spatially, China's vegetation community complexity distribution is primarily dominated by elevation, although temperature and precipitation can be locally more influential than elevation when they become the factors limiting plant growth. Temporally, China's vegetation community complexity shows a significant decreasing trend during the past 30 years, despite the observed vegetation greening trend. Prevailing climate warming across China exhibits a significant negative correlation with the decrease in vegetation community complexity, but this correlation varies with biogeographical regions. The intensity of human activities have an overall negative influence on vegetation community complexity, but vegetation conservation and restoration efforts can have a positive effect on maintaining vegetation composition complexity, informing the critical role of vegetation management policies in achieving the sustainable development goal.
Geophysical and Geotechnical Evaluation of Landslide Slip Surface in a Residual Soil for Monitoring of Slope Instability
Authors: Olabode Oladunjoye P. , Lim Hwee San , Ramli Muhd H. 
Published: June 2022

AbstractElectrical Resistivity Tomography (ERT) technique has been widely used conventionally to monitor slope instability; however, a detailed study to validate ERT models with geotechnical properties for monitoring of slope instability is still rare. The objective of this work was to evaluate soil water conditions in gravelly sand soil that influences slope instability. The ERT investigation was conducted on a 60 m survey length with 1.5 m electrodes space to obtain subsurface geological structures and geotechnical laboratory tests, and experiments were carried out to obtain soil engineering properties for validation of the ERT model results. Our results revealed three geological zones namely: saturated, weathered granite, boulders and floaters, and resistivity values of 1–800 Ωm, 1,200–4,000 Ωm, and >4,000 Ωm, respectively. The saturated zones were characterized by subsidence during dry season and possible collapsed structures of boulders and floaters during prolonged heavy rainfall. The analyzed ERT models revealed that the slip surface of a potential landslide may occur at the boundary between the saturated and weathered granite zones within 3.0 m depth. The analyzed geotechnical properties also confirmed the ERT result because the potential landslide sliding surface was delineated within 3.0 m depth at the boundary between gravelly sand with a lowest angle of internal friction of 30° and a cohesion of 8 KPa, which was easier to destroy, and silty sand with a high angle of internal friction of 33.8° and a cohesion of 12.7 KPa, which was more difficult to destroy. These findings are very fundamental in shaping the earth's surface, especially in the formation of landscapes.
Fault Zone Imaging With Distributed Acoustic Sensing: Surface‐To‐Surface Wave Scattering
Authors: Yang Yan , Zhan Zhongwen , Shen Zhichao , Atterholt James 
Published: June 2022

AbstractFault zone complexities contain important information about factors controlling earthquake dynamic rupture. High‐resolution fault zone imaging requires ﻿high‐quality data from dense arrays and new seismic imaging techniques that can utilize large portions of recorded waveforms. Recently, the emerging Distributed Acoustic Sensing (DAS) technique has enabled near‐surface imaging by utilizing existing telecommunication infrastructure and anthropogenic noise sources. With dense sensors at several meters' spacing, the unaliased wavefield can provide unprecedented details for fault zones. In this work, we use a DAS array converted from a 10‐km underground fiber‐optic cable across Ridgecrest City, California. We report clear acausal and coda signals in ambient noise cross‐correlations caused by surface‐to‐surface wave scattering. We use these scattering‐related waves to locate and characterize potential faults. The mapped fault locations are generally consistent with those in the United States Geological Survey Quaternary Fault database of the United States but are more accurate than the extrapolated ones. We also use waveform modeling to infer that a 35 m wide, 90 m deep fault with 30% velocity reduction can best fit the observed scattered coda waves for one of the identified fault zones. These findings demonstrate the potential of DAS for passive imaging of fine‐scale faults in an urban environment.
Wind‐Wave Attenuation in Arctic Sea Ice: A Discussion of Remote Sensing Capabilities
Authors: Collard Fabrice , Marié Louis , Nouguier Frédéric , Kleinherenbrink Marcel , Ehlers Frithjof , Ardhuin Fabrice 
Published: June 2022

AbstractWind‐generated waves strongly interact with sea ice and impact air‐sea exchanges, operations at sea, and marine life. Unfortunately, the dissipation of wave energy is not well quantified and its possible effect on upper ocean mixing and ice drift is still mysterious. As the Arctic is opening up and wave energy increases, the limited amount of in situ observations is a clear limitation to our scientific understanding. Both radar and optical remote sensing has revealed the frequent presence of waves in ice, and could be used more systematically to investigate wave‐ice interactions. Here we show that, in cloud‐free conditions, Sentinel‐2 images exhibit brightness modulations in ice‐covered water, consistent with the presence of waves measured a few hours later by the ICESat‐2 laser altimeter. We show that a full‐focus SAR processing of Sentinel‐3 radar altimeter data also reveals the presence and wavelengths of waves in sea ice, within minutes of Sentinel‐2 imagery. The SWIM instrument on CFOSAT is another source of quantitative evidence for the direction and wavelengths of waves in ice, when ice conditions are spatially homogeneous. In the presence of sea ice, a quantitative wave height measurement method is not yet available for all‐weather near‐nadir radar instruments such as altimeters and SWIM. However, their systematic colocation with optical instruments on Sentinel‐2 and ICESat‐2, which are less frequently able to observe waves in sea ice, may provide the empirical transfer functions needed to interpret and calibrate the radar data, greatly expanding the available data on wave‐ice interactions.
Roles of Multi‐Scale Orography in Triggering Nocturnal Convection at a Summer Rainfall Hotspot Over the South China Coast: A Case Study
Authors: Rao Xiaona , Zhao Kun , Chen Xingchao , Huang Anning , Hu Sheng , Hu Dongming , Liu Xiantong 
Published: June 2022

AbstractThe northern mountainous area of the Pearl River Delta (PRD) is a center of convection and heavy rainfall of coastal southern China during the summer monsoon season. Although there are frequent nighttime convective activities and rainfall over the region, the key dynamical and physical processes responsible for the nocturnal convection initiation (CI) are complex and not yet well documented. In this study, high‐resolution reanalyses from the Variational Doppler Radar Assimilation System (VDRAS) were used to explore the triggering mechanisms of a representative nocturnal convection event that occurred over the northern PRD on August 14, 2014. Results showed that the enhanced prevailing low‐level southerly winds, deflected easterly winds caused by the blocking of multi‐scale orography, and northern downslope winds associated with an orographic cooling effect were crucial for generating low‐level convergence and strong updrafts before CI. The low‐level convergence and moisture flux in the boundary layer started to increase at 00:20 local solar time (LST), and by the CI time (01:00 LST), the convergence intensity more than doubled. The intensification of low‐level convergence and moisture transport was strongest before 00:40 LST and was dominated by a zonal component that was closely related to the deflected easterly winds. Using Doppler radar data assimilation, this is the first study to reveal how the deflected flows and the thermally induced downslope winds combine with prevailing monsoonal winds to affect a nocturnal CI over the complex mountainous region of the South China coast.
Cell deaths: Involvement in the pathogenesis and intervention therapy of COVID-19
Authors: Li Xue , Zhang Ziqi , Wang Zhenling , Gutiérrez-Castrellón Pedro , Shi Huashan 
Published: June 2022

AbstractThe current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has dramatically influenced various aspects of the world. It is urgent to thoroughly study pathology and underlying mechanisms for developing effective strategies to prevent and treat this threatening disease. It is universally acknowledged that cell death and cell autophagy are essential and crucial to maintaining host homeostasis and participating in disease pathogenesis. At present, more than twenty different types of cell death have been discovered, some parts of which have been fully understood, whereas some of which need more investigation. Increasing studies have indicated that cell death and cell autophagy caused by coronavirus might play an important role in virus infection and pathogenicity. However, the knowledge of the interactions and related mechanisms of SARS-CoV-2 between cell death and cell autophagy lacks systematic elucidation. Therefore, in this review, we comprehensively delineate how SARS-CoV-2 manipulates diverse cell death (including apoptosis, necroptosis, pyroptosis, ferroptosis, and NETosis) and cell autophagy for itself benefits, which is simultaneously involved in the occurrence and progression of COVID-19, aiming to provide a reasonable basis for the existing interventions and further development of novel therapies.
Gene expression signatures of individual ductal carcinoma in situ lesions identify processes and biomarkers associated with progression towards invasive ductal carcinoma
Authors: Rebbeck Clare A. , Xian Jian , Bornelöv Susanne , Geradts Joseph , Hobeika Amy , Geiger Heather , Alvarez Jose Franco , Rozhkova Elena , Nicholls Ashley , Robine Nicolas , Lyerly Herbert K. , Hannon Gregory J. 
Published: June 2022

AbstractDuctal carcinoma in situ (DCIS) is considered a non-invasive precursor to breast cancer, and although associated with an increased risk of developing invasive disease, many women with DCIS will never progress beyond their in situ diagnosis. The path from normal duct to invasive ductal carcinoma (IDC) is not well understood, and efforts to do so are hampered by the substantial heterogeneity that exists between patients, and even within patients. Here we show gene expression analysis from > 2,000 individually micro-dissected ductal lesions representing 145 patients. Combining all samples into one continuous trajectory we show there is a progressive loss in basal layer integrity heading towards IDC, coupled with two epithelial to mesenchymal transitions, one early and a second coinciding with the convergence of DCIS and IDC expression profiles. We identify early processes and potential biomarkers, including CAMK2N1, MNX1, ADCY5, HOXC11 and ANKRD22, whose reduced expression is associated with the progression of DCIS to invasive breast cancer.
Bis-Schiff base linkage-triggered highly bright luminescence of gold nanoclusters in aqueous solution at the single-cluster level
Authors: Deng Haohua , Huang Kaiyuan , Xiu Lingfang , Sun Weiming , Yao Qiaofeng , Fang Xiangyu , Huang Xin , Noreldeen Hamada A. A. , Peng Huaping , Xie Jianping , Chen Wei 
Published: June 2022

AbstractMetal nanoclusters (NCs) have been developed as a new class of luminescent nanomaterials with potential applications in various fields. However, for most of the metal NCs reported so far, the relatively low photoluminescence quantum yield (QY) in aqueous solution hinders their applications. Here, we describe the utilization of bis-Schiff base linkages to restrict intramolecular motion of surface motifs at the single-cluster level. Based on Au22(SG)18 (SG: glutathione) NCs, an intracluster cross-linking system was constructed with 2,6-pyridinedicarboxaldehyde (PDA), and water-soluble gold NCs with luminescence QY up to 48% were obtained. The proposed approach for achieving high emission efficiency can be extended to other luminescent gold NCs with core-shell structure. Our results also show that the content of surface-bound Au(I)-SG complexes has a significant impact on the PDA-induced luminescence enhancement, and a high ratio of Au(I)-SG will be beneficial to increasing the photoluminescence intensity of gold NCs.
Nickel(0)-catalyzed divergent reactions of silacyclobutanes with internal alkynes
Authors: Wang Xi-Chao , Li Bo , Ju Cheng-Wei , Zhao Dongbing 
Published: June 2022

AbstractTransition metal-catalyzed reactions of silacyclobutanes with a variety of π units have attracted much attention and become one of the most straightforward and efficient approaches to rapidly access structurally diverse organosilicon compounds. However, the reaction of silacyclobutanes with alkynes still suffers from some limitations: (1) internal alkynes remain challenging substrates; (2) expensive Pd- or Rh-based catalysts have been employed in all existing systems; (3) controlling chemodivergence has not yet been realized. Herein we realize Ni-catalyzed chemodivergent reactions of silacyclobutanes with alkynes. In comparison with the previous Pd or Rh catalytic systems, our Ni-catalytic system features: 1) complementary substrate scope; 2) ligand-controlled chemodivergence; 3) low cost. The ligand precisely dictates the pathway selectivity, leading to the divergent formation of (benzo)silacyclohexenes and allyl vinylsilanes. Moreover, we demonstrate that employment of a chiral phosphine ligand is capable of forming silicon-stereogenic allyl vinylsilanes in high yields and enantioselectivities. In addition, DFT calculation is performed to elucidate the origin of the switchable selectivities, which is mainly attributed to different ligand steric effects.
Detection of quantum-vacuum field correlations outside the light cone
Authors: Settembrini Francesca Fabiana , Lindel Frieder , Herter Alexa Marina , Buhmann Stefan Yoshi , Faist Jérôme 
Published: June 2022

AbstractAccording to quantum field theory, empty space—the ground state with all real excitations removed—is not empty, but filled with quantum-vacuum fluctuations. Their presence can manifest itself through phenomena such as the Casimir force, spontaneous emission, or dispersion forces. These fluctuating fields possess correlations between space-time points outside the light cone, i.e. points causally disconnected according to special relativity. As a consequence, two initially uncorrelated quantum objects in empty space which are located in causally disconnected space-time regions, and therefore unable to exchange information, can become correlated. Here, we have experimentally demonstrated the existence of correlations of the vacuum fields for non-causally connected space-time points by using electro-optic sampling. This result is obtained by detecting vacuum-induced correlations between two 195 fs laser pulses separated by a time of flight of 470 fs. This work marks a first step in analyzing the space-time structure of vacuum correlations in quantum field theory.