bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surgical tactics in peritonitis, caused by complicated course of colorectal cancer
Authors: Karol I. V. 
Published: December 2022

Objective. To improve surgical tactics in peritonitis, caused by complicated course of colorectal cancer.
Materials and methods. Through the 2017 - 2020 yrs period in Department of Surgery in Brovary Multidisciplinary Clinical Hospital 18 patients with colorectal cancer, complicated by peritonitis, were operated. Among them there were 14 (77.8%) men and 4 (22.2%) women, ageing in spectrum 42 – 83 yrs old. In 12 (66.7%) patients the cancer of Stage III was diagnosed, while in 6 (33.3%) – Stage ІV.
Results. The right-sided hemicolectomy was performed in 22.2% of the patients, resection of transverse colon – in 3 (16.7%), a left-sided hemicolectomy – 1 (5.6%), Hartmann operation – 9 (50.0%), subtotal colectomy – 1 (5.6%). All the operations were performed without formation of primary anastomoses, and with stoma construction in proximal part of intestine. Reoperation were performed in 4 (22.2%) patients. There were 3 (16.7%) postoperative deaths – in patients with the cancer Stage IV, peritonitis in a terminal stage – due to development of the polyorgan insufficiency syndrome.
Conclusion. Formation of primary interintestinal anastomoses while doing surgical intervention for colorectal cancer, complicated by peritonitis, is contraindicated because of high risk of the sutures insufficiency presence.
Security and efficacy of intravenous injection of lidocaine in major hepatic resection
Authors: Zatsarynnyi R. A. , Sydiuk O. E. , Pidopryhora O. O. 
Published: December 2022

Objective. To determine in dynamics the blood lidocaine concentration in the patients while performing major hepatic resection with its epidural and intravenous injection for intra– and postoperative anesthesia and to estimate the toxicity potential.
Materials and methods. Into the investigation 27 patients were included, to whom hepatic resection with preservation of 30 – 60% of parenchyma was done. In all the patients multicomponent intraoperative anesthesia was applied. Depending on adjuvant used, the patients were divided into two groups: the first – 7 patients, in whom intravenous lidocaine injection was applied, and the second – 20 patients, in whom multicomponent anesthesia was added by thoracic epidural anesthesia.
Results. In 2 h postoperatively a tendency towards enhanced blood concentration of lidocaine was observed by 28.8% after its epidural injection, comparing with intravenous injection – 2.37 and 1.84 mcg/ml (р=0.29) accordingly without principal difference in 14 h after the operation – 2.85 and 2.62 mcg/ml (р=0.76) accordingly. In no one patient toxic life–threatening reactions were registered.
Conclusion. The adjuvant application of lidocaine for intra– and postoperative anesthesia, using intravenous and epidural introduction in major hepatic resection performance, do not lead to raising of the medicinal compound concentration in the blood higher than conventional toxic content. The blood concentration of the preparation while its epidural introduction may be higher, than in intravenous introduction, witnessing in favor of secureness of intravenous application of lidocaine and at the same time a statistically significant difference between indices of its concentration in various ways of introduction was not observed.
Teknik Fotografi dan Analisa Semiotika dalam Photoshoot Challenge Romance in Rain INTM Cycle 2
Authors: Santika Aprilia , Sari Maya Purnama 
Published: December 2022

In this study, the author analyzes and discusses photography techniques seen from the photos in the Photoshoot Challenge Romance in Rain INTM Cycle 2 and analyzes the semiotics of the photos based on the theory of Charles Sanders Peirce. Then in the method taken here the author uses a qualitative method, because here the author needs various references from articles, journals, social media, books, and others. Where the photos of the six models analyzed are Helen Hiu, Sarah Tumiwa, Faradina Amalia, Peace Jemima Okechukwu Nnatuanya, Audya Ananta, dan Tiffany Regina. The result of the analysis was obtained which interpreted the pose movements carried out by the model in the photoshoot in the presence of rain falling and it was explained that the techniques used were full shot shooting techniques and how to take photos in rainy conditions. Key words: Photography, Semiotics, Model
Perkembangan Teknologi Informasi dan Komunikasi terhadap Perubahan Sistem Komunikasi Indonesia
Authors: Wiryany Detya , Natasha Selina , Kurniawan Rio 
Published: December 2022

The role of information and communication technology is no less important than human food and clothing needs. A technology is essentially created to make human life easier and more comfortable. Through communication, humans build themselves and their environment, and through communication, human civilization becomes dynamic. This research method is descriptive qualitative with purposive sampling technique in determining five informants. Data collection techniques by observation, documentation and interviews and using data analysis Miles and Huberman. The existence of technology at that time helped the government's communication process, facilitated access to information, shortened time and cut costs. The development of information and communication technology is progressing very rapidly at this time so that it triggers changes in Indonesia's communication system. In conveying information or messages to other communities in urban and rural areas, of course, it was still very limited in the past, technology with all-improvement was very difficult to obtain information or communicate. Along with developments, today's communication system changes everything to be very easy and sophisticated.Keywords: Development of Technology, Information, Communication Systems
Women's Silence Imaginative-Proximity in Media
Authors: Saudah Saudah , Adi Dodot Sapto 
Published: December 2022

The condition of society is equal to the need for information presented in the mass media. This uniqueness places women in an important position in finding the existence of the media. Women have a dual position as creators and connoisseurs of mass media, because there is sufficient time to utilize the media as a solution. The growing phenomenon lies in the reality that can be formed from the conditions created between women, and conventional mass media as well as renewable media. By conducting in-depth interviews, the results show that the media has the ability to form and strengthen identities, and get closer to the media, so that they can carry out the process of adapting to the patterns presented by the media. This situation causes the emergence of women's closeness to the mass media which is shrouded in a distinctive imagination. Each will mean the information presented, and provide a process of knowing, imitating, and forming identity on the mass media.Keywords: Women, Mass Media, Medium Wise
Effect of Fibers Orientation on the Nonlinear Dynamic Performance of Laminated Composite Plate under Different Loading In-plane
Authors: Mohammed Wisam Hamzah , Shambina Svetlana , Ammash Haider Kadhim 
Published: December 2022

Non-linear dynamic analysis of a cross-ply laminated composite with fibre spacing plates under in-plane loading was presented. The mathematical formulation is based on first-order shear deformation theory and von-Karman non-linearity. Eight-node isoperimetric quadrilateral elements with five degrees of freedom per node were used to maintain geometric nonlinearity. In this investigation, a variety of fiber spacings and fibre orientations were used for the purpose of studying the effect of improvements on the behaviour of samples with this type of load. The dynamic equilibrium equations were solved using the Newmark integration technique. The non-linear dynamic analysis addressed several functions of changing fibre spacing with various changes in volume percentage and diverse fibre orientations. Fibre orientation, volume fraction fluctuation, and fibre distribution significantly affected laminated composite plates' non-linear dynamic behaviour. This study showed that the combination of improvements does not give a clear vision of the ideal improvement, and the best case for fibre distribution and the best case for layer rotation and combination should be studied to know the effect of the ameliorations one on the other and distinguish the impact of the transverse loading pattern in one direction on rotating the sample layers with axial load in one direction, so that changing the fibre distribution is more effective in the behaviour and stability of the plate by taking advantage of the orientation change, as demonstrated in this paper. Doi: 10.28991/CEJ-2022-08-12-03 Full Text: PDF
The Impact of the Environment and People’s Attitudes on Greywater Management in Slum Coastal Settlements
Authors: Asmal Idawarni , Syarif Edward , Amin Samsuddin , Walenna Muhammad A. 
Published: December 2022

The rapid population growth in many countries will ultimately impact the provision of essential services and engender many challenges, such as inadequate sanitation. Indonesia has an extensive coastline and densely populated coastal areas that have grown sporadically, creating slums. These areas have long been associated with poor greywater management. Greywater is dumped into beaches, roads, and yards without pre-treatment, thus harming the environment and society. This study aims to identify various factors influencing community actions to manage and overcome greywater-related problems in coastal slum areas. Using methods by combining qualitative and quantitative approaches. The influential factors in the physical condition of the built environment, the natural environment, community activities, and government involvement related to greywater were analyzed qualitatively, while the public understanding of greywater management was assessed quantitatively. The results showed that these four factors significantly influenced people's attitudes towards wastewater treatment. The findings show that these four factors affect people's mind-set about handling greywater, which becomes an obstacle to changing their attitudes and views on greywater. The four factors have the same level and cannot be separated in dealing with greywater. Treatment strategies are in accordance with coastal nature, settlements physical conditions and communities are then chosen Treatment Horizontal Flow. Doi: 10.28991/CEJ-2022-08-12-05 Full Text: PDF
Assessment of reference intervals of acylcarnitines in newborns in Siberia
Authors: Nemchinova N. V. , Bairova T. A. , Belskikh A. V. , Bugun O. V. , Rychkova L. V. 
Published: December 2022

Background. The incidence of diseases associated with impaired transport and oxidation of fatty acids is from 1:5,000 to 1:9,000 newborns. High morbidity, risk of death in the absence of timely correction, non-specificity of clinical manifestations define the importance of their timely laboratory diagnosis based on the determination of free carnitine and acylcarnitines in the blood. Reference values for free carnitine and acylcarnitines vary in different populations. The aim. To determine the reference intervals of free carnitine and acylcarnitines in newborns of the Irkutsk region and to compare them with similar reference intervals in newborns in other countries. Methods. The analysis of 229 samples of drу blood spots of healthy newborn children of the Irkutsk region aged from 0 to 7 days was carried out. Analysis of acylcarnitine concentrations was performed using high performance liquid chromatography with tandem mass spectrometry. Results. 2.5 and 97.5 percentiles (µmol/l) were calculateed for 13 acylcarnitines: C0 – [8.78; 38.08]; C2 – [3.55; 19.09]; C3 – [0.33; 1.96]; C4 – [0.08; 0.51]; C5 – [0.06; 0.44]; C5DC – [0.03; 0.17]; C6 – [0.01; 0.07]; C8 – [0.01; 0.07]; C10 – [0.02; 0.07]; C12 – [0.04; 0.51]; C14 – [0.07; 0.24]; C16 – [0.58; 3.25]; C18 – [0.35; 1.16]. Conclusion. Differences in acylcarnitine reference intervals were found: compared with other countries, the concentrations of reference intervals for C0, C2, C3, C5DC, C8, C10, C14, C16 and C18 were lower in our study, reference intervals for C5 and C12 were higher in our country.
Effect of different types of immunosuppressive therapy on the parameters of TNF receptor expression in patients with rheumatoid arthritis
Authors: Alshevskaya A. A. , Zhukova J. V. , Lopatnikova J. A. , Kireev F. D. , Shkaruba N. S. , Chumasova O. A. , Shevchenko J. A. , Ilina N. A. , Sizikov A. E. , Sennikov S. V. 
Published: December 2022

Background. The balance of TNF receptor expression on immune cells is a key factor determining cytokine-induced activation of proapoptotic or proliferative signaling pathways. As a result, the changes in cytokine level and in expression of its receptors may be one of the mechanisms that regulate the level of systemic and local inflammation in rheumatoid arthritis (RA) and determine the degree of therapy effectiveness. The aim. To study the effect of rheumatoid arthritis therapy on the change in the patterns of TNF receptors expression in terms of co-expression and the number of receptors on the main subpopulations of immunocompetent cells.Materials and methods. A comparative analysis of the profiles of TNF receptors type 1 and 2 (TNFR1/2) co-expression was carried out in patients with RA (n = 16) before and after having inpatient effective therapy and in comparison with a group of healthy individuals (n = 21). We compared the number of receptors and the proportion of cells expressing the corresponding receptor using flow cytometry and studied the subpopulations of regulatory T cells, T cells, B cells, and monocytes. Results. In patients with RA, there is a significant redistribution of TNFR1 and TNFR2 expression on immunocompetent cells, while the intensity of changes is associated not only with disease severity indicators, but also with the therapy received. The key adaptive mechanism of the TNF system in long-term treatment refractory course of RA is a change in the proportion of double-positive TNFR1+TNFR2+ cells, while the effectiveness of therapy and clinical indicators of the disease severity are associated with individual variability in the parameters of type 2 receptors expression. Conclusions. The data obtained confirm the existence of a relationship between an imbalance in the expression of type 1 and type 2 TNF receptors on immunocompetent cells and the effectiveness of response to therapy. The identified patterns of typical changes in TNFR1/2 co-expression in RA can be used as potential therapeutic targets and predictive factors for the effectiveness of therapy.
Comparison of attitude of Indian and Russian parents to children’s vaccination
Authors: Novikova E. A. , Krishna M. G. M. , Sureshkumar Aaromal A. , Suprasannan A. , Vanyarkinа A. S. , Moskaleva E. V. , Petrova A. G. , Rychkova L. V.  
Published: December 2022

Background. The vaccine preventable diseases outbreaks have become more frequent in recent decades and the lack of global vaccine awareness has been increasing and deteriorating vaccine compliance. The aim. To assess the attitude towards vaccination of parents from India and Russia. Methods. 1620 parents from Russia (Irkutsk city) and 214 parents from India (Kerala state) took part in the international cross-sectional multicenter study via survey method. Results. Parents from both countries showed good adherence to vaccination, only 1 % of Indians and 2 % of Russians did not vaccinate their children. More than 90 % of Russians took information from pediatricians compared with other sources with a prevalence of pediatricians working in the public health system 91.7 % (95 % CI: 90.2–92.9), whereas only 50 % of Indians were informed about vaccination from pediatricians (p < 0.0001). The main source of vaccine information for Indian parents was Internet (52.8 %; 95 % CI: 46.1–59.3) and mass-media (83.6 %; 95% CI: 78.1–87.9), whereas Russians resorted to this source much less (0.3 %; 95 % CI: 0.1–0.7 for Internet; and 4.3 %; 95 % CI: 3.4–5.4 for mass-media; p < 0.0001). Interestingly, while the vast majority of Russians received information about vaccination from a pediatrician, 71.2 % (95 % CI: 68.9–73.3) wanted to know more. Indians suffered from a lack of information too, but not as much (63.1 %; 95 % CI: 56.4–69.3; p = 0.01). Conclusion. Despite of a good attitude to vaccination of parents from India and Russia the lack of vaccine information was registered.
Development of cardioprotective effect of chronic continuous hypoxia in rats with induced metabolic syndrome
Authors: Derkachev I. A. 
Published: December 2022

Background. It is known that adaptation to chronic continuous hypoxia leads to a pronounced cardioprotective effect. The efficiency of acute adaptation to hypoxia is reduced in metabolic syndrome. However, the effectiveness of the myocardial infarct size-limiting effect of chronic continuous hypoxia in metabolic syndrome remains an understudied fact. The aim. To study the effectiveness of the development of the myocardial infarct size-limiting effect of chronic continuous hypoxia in rats with metabolic syndrome. Materials and methods. The study was carried out on 43 Wistar rats. Adaptation of animals to chronic hypoxia was performed during 21 days in a hypoxic chamber (12 % O2, 0.3 % CO2). Metabolic syndrome was modeled by keeping rats on a high-carbohydrate and high-fat diet (proteins 16 %, fats 21 %, carbohydrates 46 % (including fructose 17 %), cholesterol 0.125 %, cholic acid 0.5 %) for 12 weeks with replacement of drinking water with 20% fructose solution. Coronary occlusion-reperfusion was performed in vivo. The effect of chronic hypoxia and metabolic syndrome on myocardial infarct size was assessed. Results. It was found that myocardial infarct size in rats after chronic continuous hypoxia was 38 % less than in animals of the control group. In rats which were kept on a high-carbohydrate and high-fat diet we observed the obesity, decreased glucose tolerance, increased serum triglycerides level, and hypertension. Adaptation to chronic continuous hypoxia in animals on a high-carbohydrate and high-fat diet improved carbohydrate metabolism, but did not affect the severity of other metabolic disorders. At the same time, the myocardial infarct size-limiting effect of chronic hypoxia was not observed in rats with metabolic syndrome. Conclusion. Metabolic syndrome eliminated myocardial infarct size-limiting effect of chronic continuous hypoxia.
Influence of psychosocial factors at work on the non-departmental security officers of the National Guard of the Russian Federation
Authors: Korneeva A. V. , Korneeva Ya. A. 
Published: December 2022

An analysis of modern research has shown insufficient study of the labor factors that influence the development of various functional states of non-departmental security officers which allow to develop the recommendations to improve their psychological safety. The aim of the study. To identify and to describe psychosocial factors at work in relation to the general functional state of the body, stress and performance of non-departmental security officers. Methods. We used the General Nordic Questionnaire for Psychological and Social Factors at Work (QPSNordic), psychophysiological testing using “Psychophysiologist” device, M. Lüscher color preference test, multivariate statistical methods. The study involved 74 non-departmental security officers of the Arkhangelsk region. Results. The general functional state of the body, stress and performance, measured by objective and projective methods, are differentially interconnected with psychosocial factors at work. The general functional state of the body is related with the personal attitude to the work performed; stress and performance – with factors of social support, organizational culture and work requirements. The general functional state of non-departmental security officers is favorably influenced by such factors as understanding the goals of the work performed and the expected results, satisfaction with the quality of work and labor safety. Insufficient ability to maintain good relations with the team unfavorably influences the general functional state of the officers. The factors of work intensity include one-type tasks, tight schedule, increased alertness during work and greater precision in movements. Risk factors are associated with strict working hours and insufficient attention of the manage-ment to the opinion and interests of subordinates. At the same time, the environmental resource is the possibility of realizing professional motives and demonstrating mastery in work, as well as a favorable organizational culture.
Production of reactive oxygen species by neutrophils and macrophages of F1 hybrid mice (C57Bl6xCBA) in response to stimulation with cucurbit(n)urils (n = 6, 7, 8)
Authors: Aktanova A. A. , Pashkina E. A. , Boeva O. S. , Feofanova N. A. , Kozlov V. A. 
Published: December 2022

Background. Due to their very small size, nanomaterials, in particular cucurbiturils, have unique physical and chemical properties that find their application in medicine. However, the toxicity of cucurbiturils is not fully understood; in particular, we are interested in the immunological safety of their use. One of the mechanisms of nanotoxicity is the formation of reactive oxygen species (ROS) by macrophages and neutrophils. Hyperproduction of ROS can lead to oxidative stress and further damage to cell DNA with loss of physiological function and development of pathology. The aim. Evaluation of the effect of cucurbit[n]urils (n = 6, 7, 8) on the production of reactive oxygen species by mice macrophages and neutrophils. Materials and methods. F1 hybrid mice (CBAxC57Bl/6) aged 2 months (n = 11) were used in the work. Evaluation of superoxide radical production by peritoneal mouse neutrophils and macrophages was carried out by spectrophotometric method for determining the reduction of p-nitroblue tetrazolium (NBT) to formazan. Results. It was shown that CB[6] and CB[7] at concentrations of 0.5 and 0.3 mM do not have an inhibitory effect on ROS synthesis, but, on the contrary, significantly increase ROS production by macrophages. In addition, CB[6] 0.3 mM increases the level of ROS in neutrophils. Conclusion. Cucurbiturils can lead to an increase in the production of ROS in immunocompetent cells, depending on the concentration used (0.3 mM and higher).
Analisis Perbandingan Biaya Pekerjaan Bekisting Konvensional dan Bekisting Sistem Pada Bangunan Gedung
Authors: Guspari Oni , Mafriyal Mafriyal , Hidayati Rahmi , Mirani Zulfira , Amelia Picko Wike 
Published: December 2022

Formwork is a temporary concrete mold that holds the concrete from fresh concrete until the concrete reaches sufficient strength. Besides the strength and easy to implementation, the cost of formwork is important thing to consider. In this study, the cost of column, beam and floor slab formwork will be analyzed by comparing the conventional formwork and system formwork on the 1st floor of the IAIN Bukittinggi Laboratory Development Project.
This research begins by collecting the main data, namely shop drawings so that the volume and also cost of formwork can be calculated. For analysis conventional formwork using the unit price analysis based on the PUPR Ministerial Regulation 2018, but for price of materials and worker wages based on the Bukittinggi area in 2019. While for system formwork, the rental price based on formwork and scaffolding company, PT. Wijaksana Perkasa Beton.
The result of this study indicated that for the 1st floor of the Laboratory Development Project of IAIN Bukittinggi, the cost of system formwork is more expensive than conventional formwork, i.e Rp 381,260,039.29 for system formwork compared to Rp 336,629,299.41 for conventional formwork. The results of this study also have not compared of the speed and ease of carrying out the work between the two types of formwork which will be investigated in the next stage.