bluuebunny/crossref_metadata_2025_split huggingface dataset:
Custom-made triflanged implants in reconstruction of severe acetabular bone loss with pelvic discontinuity after total hip arthroplasty consecutive cohort study
Authors: Winther Sebastian S. , Petersen Michael , Yilmaz Müjgan , Kaltoft Nicolai S. , Stürup Jens , Winther Nikolaj S. 
Published: November 2022

Aims Pelvic discontinuity is a rare but increasingly common complication of total hip arthroplasty (THA). This single-centre study evaluated the performance of custom-made triflange acetabular components in acetabular reconstruction with pelvic discontinuity by determining: 1) revision and overall implant survival rates; 2) discontinuity healing rate; and 3) Harris Hip Score (HHS). Methods Retrospectively collected data of 38 patients (39 hips) with pelvic discontinuity treated with revision THA using a custom-made triflange acetabular component were analyzed. Minimum follow-up was two years (mean 5.1 years (2 to 11)). Results There were eight subsequent surgical interventions. Two failures (5%) of the triflange acetabular components were both revised because of deep infection. There were seven (18%) patients with dislocation, and five (13%) of these were treated with a constraint liner. One patient had a debridement, antibiotics, and implant retention (DAIR) procedure. In 34 (92%) hips the custom-made triflange component was considered stable, with a healed pelvic discontinuity with no aseptic loosening at midterm follow-up. Mean HHS was 80.5 (48 to 96). Conclusion The performance of the custom triflange implant in this study is encouraging, with high rates of discontinuity healing and osteointegration of the acetabular implant with no aseptic loosening at midterm follow-up. However, complications are not uncommon, particularly instability which we successfully addressed with constrained liners. Cite this article: Bone Jt Open 2022;3(11):867–876.
Multimorbidity and depressive symptoms in older adults and the role of social support: Evidence using Canadian Longitudinal Study on Aging (CLSA) data
Authors: Zhang Lixia , Shooshtari Shahin , St. John Philip , Menec Verena H. 
Published: November 2022

BackgroundThe rising prevalence of multimorbidity poses challenges to health systems globally. The objectives of this study were to investigate: 1) the association between multimorbidity and depressive symptoms; and 2) whether social support plays a protective role in this association.MethodsA prospective population-based cohort study was conducted to analyze baseline and 3-year follow-up data of 16,729 community dwelling participants aged 65 and above in the Canadian Longitudinal Study of Aging (CLSA). Multimorbidity was defined as having three or more chronic conditions. The 10-item Center for Epidemiologic Studies Depression scale (CESD-10) was used to measure depressive symptoms. The 19-item Medical Outcomes Study (MOS) Social Support Survey was employed to assess perceived social support. Multivariate logistic regression models were used to examine the association between multimorbidity, social support and depressive symptoms.ResultsMultimorbidity was very common among participants with a prevalence of 70.6%. Fifteen percent of participants had depressive symptoms at baseline. Multimorbidity was associated with increased odds of having depressive symptoms at 3-year follow-up (adjusted odds ratio, aOR = 1.51, 95% CI 1.33, 1.71), and developing depressive symptoms by follow-up among those with no depressive symptoms at baseline (aOR = 1.65, 95% CI 1.42, 1.92). Social support was consistently associated with decreased odds of depressive symptoms, regardless of level of multimorbidity.ConclusionMultimorbidity was positively associated with depressive symptoms over time, but social support served as a protective factor. As a modifiable, protective factor, emphasis should be placed in clinical practice to assess social support and refer patients to appropriate services, such as support groups. Similarly, health policy should focus on ensuring that older adults have access to social support opportunities as a way to promote mental health among older adults. Community organizations that offer social activities or support groups play a key role in this respect and should be adequately supported (e.g., with funding).
Impact of prothrombin and factor V Leiden mutations on the progression of fibrosis in patients with chronic hepatitis C
Authors: Naguib Mary , Abdel-Razek Wael , Estaphan Suzanne , Abdelsameea Eman , Abdel-Samiee Mohamed , Shafik Nevine F. 
Published: November 2022

BackgroundThe role of thrombotic factors in the pathogenesis and progression of liver fibrosis remains obscure. We aimed to study the relationship between prothrombin G20210A (PT20210) and factor V Leiden (FVL) mutations and the progression of fibrosis and liver function in chronic HCV patients.MethodsThe study included 100 subjects, 88 patients with HCV-related cirrhosis (compensated: 38, decompensated: 50), and 12 controls. Patients with other viral hepatitis or coinfection, inherited metabolic disease, autoimmune hepatitis, hepatic or extrahepatic malignancy, in addition to patients with causes of hypoalbuminemia, elevated bilirubin or prolonged INR not related to cirrhosis were excluded from the study. Relevant clinical data were collected and basic laboratory tests were performed. Liver fibrosis was assessed using APRI and FIB-4 scores. FVL and PT20210 mutations were analyzed.ResultsFVL and PT20210 mutations were significantly higher in decompensated vs. compensated patients (32% vs. 5.3%, P = 0.001; 20% vs. 5.3%, 0.043, respectively) and absent in controls. Both mutations significantly correlated to the duration of infection, platelet count and fibrosis scores. PT20210 mutation significantly correlated to serum albumin and INR. Both mutations significantly predicted fibrosis scores, especially PT20210 (AUROC: 0.833 for APRI and 0.895 for FIB-4).ConclusionsBoth mutations are significantly correlated to fibrosis progression and liver profile and could be considered as markers predicting the need for early and different intervention.
The effect of COVID-19 vaccination on the menstrual pattern and mental health of the medical students: A mixed-methods study from a low and middle-income country
Authors: Kareem Rabia , Sethi Mifrah Rauf , Inayat Sumaira , Irfan Muhammad 
Published: November 2022

Objective
To assess the effect of COVID-19 vaccination on menstrual patterns and mental health of medical students and to explore the students’ perspective regarding this effect.

Materials and methods
This mixed-method study was conducted on the medical and dental students of the private and public sector institutions of Peshawar from September 2021 to March 2022. A Menstrual symptom questionnaire (MSQ) and hospital anxiety and depression scale (HADS) were used. This was followed by qualitative interviews with the students who faced problems in their menstruation after the COVID-19 vaccination.

Results
A total of 953 students were included, with a mean age of 20.67±1. 56 years. More than half (n = 512, 53.7%) experienced menstrual cycle abnormalities post-vaccination. The majority having disturbances in their menstrual cycle had significantly higher levels of anxiety (p = 0.000). Results on the menstrual symptom questionnaire, anxiety, and depression subtype of HADS showed a negative and statistically significant relationship with changes after COVID-19 vaccination (p<0.05). In the qualitative interviews, 10 (58.8%) students each had problems with frequency and flow, followed by 7 (41.2%) students, who had dysmenorrhea. Seven (41.2%) consulted a gynecologist for management. The majority (n = 14, 82.4%) stated that these issues had an adverse impact on their mental health and almost half (n = 8, 47.1%) suggested consulting a gynecologist while facing such situations.

Conclusion
This study showed the impact of the COVID-19 vaccine on women`s menstrual patterns and subsequent mental health status. Although the majority of the students experienced menstrual cycle abnormalities and subsequent mental health adversities post COVID-19 vaccination but these were temporary and self-limiting and were attributed to the psychological impact of the vaccination. Therefore, it is imperative to alert health care professionals about possible side effects and prior counseling is expected to play an important role in this context.
Household fuel use and its association with potential respiratory pathogens among healthy mothers and children in Ethiopia
Authors: Tamire Mulugeta , Addissie Adamu , Gizaw Solomon , Abebe Tamrat , Geravandi Shadi , Nilsson Staffan , Gonzales-Siles Lucia , Nordén Rickard , Andersson Rune , Skovbjerg Susann 
Published: November 2022

BackgroundOver 90% of Ethiopians still rely on solid fuels for cooking food. The pollution from the burning process causes adverse respiratory outcomes including respiratory infections. This study aimed to assess the association of the pollution with nasopharyngeal occurrence of potential pathogens.MethodsWe conducted a comparative cross-sectional study in urban and rural settings in Ethiopia in 2016. Questionnaire-based data were collected from 168 mothers and 175 children aged below two years. Multiplex real-time PCR assays were performed on nasopharyngeal secretions for detection of bacteria and viruses and for the identification of pneumococcal serotypes/groups.ResultsHigh rates of bacteria and viruses in the nasopharynx were detected by PCR among both the children and the mothers. Among the detected viruses, enterovirus was more commonly detected among rural children than among children from urban areas.Streptococcus pneumoniaeandHaemophilus influenzaewere both more prevalent among children and mothers from rural areas compared with urban groups and among those using solid fuels compared with cleaner fuel users. Children from rural households using solid fuels and children whose mothers had educational status below high school had four times higher odds for detection ofS.pneumoniaecompared with those households using cleaner energy or those children having mothers with a higher educational status, respectively. One or more serotype/serogroup was identified in about 40% of the samples that were positive for pneumococci. Out of all identified serotypes/serogroups, 43% in the children and 45% in the mothers belonged to PCV13, indicating the larger majority of detected pneumococci being non-PCV13 serotypes.ConclusionThis study presented a high carriage rate ofS.pneumoniaeandH.influenzaeamong both children and their mothers, especially in rural areas and among solid fuel users. Thus, interventions should target cleaner energy sources to the public and promote maternal education.
Knowledge, attitudes and preventive practices towards COVID-19 among workers at two points of entry in South-Eastern Botswana: A cross-sectional study
Authors: Siamisang Keatlaretse , Mokgethi Naledi , Lesetedi Onalethata , Selemogo Mpho 
Published: November 2022

Introduction
Adherence to control measures and provision of appropriate information at international borders and points of entry (POE) are key to limiting the importation of COVID-19. This study aimed to describe the knowledge, attitudes, and practices (KAPs) of POE staff towards COVID-19 in Botswana.

Methods
This was a cross-sectional study of the COVID-19 KAPs among workers at Tlokweng border and Sir Seretse Khama International Airport (SSKIA) using a self-administered questionnaire. The tool incorporated the participants’ demographics and selected questions on COVID-19 KAPs. Analysis was descriptive. Categorical data were summarized with frequencies while numeric data were summarized with medians and interquartile ranges (IQR). The total knowledge and practice scores of each individual were computed by adding their individual scores for each question. The scores were then categorized according to Bloom’s cutoffs of good (80–100%), moderate (60–79%) and poor (<60%).

Results
A total of 276 individuals participated in the study. Of these, 70 were from Tlokweng border and 206 were from SSKIA. The participants performed worst on questions on the frequency of severe disease and asymptomatic transmission of COVID-19. The attitudes were mainly positive. However, 54.6% of participants thought that the COVID-19 burden is exaggerated. For practice, the worst performance was on social distancing, sanitizing shared surfaces, and going to work while symptomatic. Overall, good and moderate knowledge was observed in 47.8% and 38.0% of participants, respectively. Similarly, good and moderate performance on practices was observed in 63.6% and 24.4% of participants respectively.

Conclusion
The knowledge, attitudes, and practices were generally good at the 2 points of entry. More than 85% of respondents had moderate or good performance on knowledge and practice questions. However, the respondents performed poorly in some key questions. Targeted health information and promotion must address the identified gaps.
Developments in the History of Arbitration
Authors: Boorman Francis Calvert 
Published: November 2022

It is not always easy to see the relevance of history to current practice, a complaint that might be levelled at the history of arbitration. Yet the uses made of history in work about the present state of arbitration show that some fascinating interventions have been made by both eminent academics and practitioners, with some important differences emerging in their interpretations. This article gives a brief overview of the history of legislation relating to arbitration, which predominantly relates to the relationship of arbitration with commerce and the courts. It also suggests that recent developments in studies of the history of arbitration challenge some of the assumptions made by those using it to illuminate the present. One particular difficulty with the way history has been used is the tendency to focus exclusively on commercial arbitration. Two detailed examples are given of areas that have received less attention; arbitration in the early railway industry and its use settling disputes for working-class friendly societies. These point the way to exploring a more diverse history, that looks beyond London, lawyers and commerce.
Keywords: arbitration; dispute resolution; history; Georgian; Victorian; railways; friendly societies; legislation.
Case Transcript - Bates v Post Office Limited, TLQ 17 4055 Day 6 19 March 2019
Authors: Case Transcript England & Wales 
Published: November 2022

Case Transcript - Bates v Post Office Limited, TLQ 17 4055
Day 6 19 March 2019
England & Wales; theft; electronic evidence; Post Office Horizon System; ‘reliability’ of computers
Case Transcript - Bates v Post Office Limited, TLQ 17 4055 Day 17 7 June 2019
Authors: Case Transcript England & Wales 
Published: November 2022

Case Transcript - Bates v Post Office Limited, TLQ 17 4055
Day 17 7 June 2019
England & Wales; theft; electronic evidence; Post Office Horizon System; ‘reliability’ of computers
Revising the Saudi Electronic Transactions Law on E-Signatures
Authors: Kinsara Oways 
Published: November 2022

Acknowledging the ever-increasing significance of the Kingdom of Saudi Arabia in the global e-commerce market, this article critically examines the e-signature regime of the 2007 Saudi Electronic Transactions Law and its implementing regulation. In doing so, it considers the evolution of the European regime on e-signatures, from Directive 1999/93/EC to Regulation (EU) No 910/2014 (the eIDAS Regulation). The article primarily concludes that the Saudi legislature’s approach to e-signatures has been overly restrictive and calls for different, permissive and careful consideration.

Index words: Electronic signature, e-commerce, e-transactions, Saudi Arabia, European Union, eIDAS Regulation, comparative analysis.
Electronic Execution of Documents Interim Report
Authors: King Mark 
Published: November 2022

An Industry Working Group set up by a public appointments competition has recently produced Electronic Execution of Documents Interim Report via the Ministry of Justice. The Law Commission dealt with this issue in 2019 in Electronic execution of documents (Law Com No 386, HC2624) and it was suggested that uncertainties may have influenced the degree of confidence of users. The aim of this article is to provide a critical analysis of the Interim Report and its uncritical acceptance of the suggestion.
Index words: Ministry of Justice; England & Wales; electronic execution; electronic documents; electronic signatures; recommendations
Delfim Santos e os temas culturais
Authors: De Carvalho José Maurício 
Published: November 2022

Resumo: Nesse estudo examinamos os temas culturais considerados por Delfim Santos como porção significativa do ser do homem. Ele examinou a linguagem, a produção técnica, a consciência científica, os costumes, os valores, a educação, o conceito de filosofia, a história.
Palavras-chave: homem; cultura; espírito objetivo.

Résumé: Dans cette étude nous examinons les thémes culturels considérés par Delfim Santos comme parcelle significative de l'homme. 11 a examiné le langage, la production technique, la conscience scientifique, les valeurs, l'éducation, le concept de la philosophie, l'histoire.
Mots-clé: homme; culture; esprit objectif.
problema da linguagem na transição da filosofia humanista para a filosofia moderna
Authors: Guido Humberto Aparecido de Oliveira 
Published: November 2022

Resumo: Este artigo introduz a problemática da ruptura epistemológica ocorrida durante a passagem da Filosofia Humanista para a Filosofia Moderna, apresentando a linguagem como elemento de descontinuidade na transição entre um período e outro. A argumentação reforça os elementos comuns aos dois períodos para apresentar a linguagem como mudança de paradigma do estudo da natureza, sendo a matemática, além da sua correspondência com a estrutura da mente humana, essa nova forma de linguagem que instaura a representação como a possibilidade única para a expressão da verdade.
Palavras-chave: Humanismo; Modernidade; Linguagem; Filosofia da Ciência.

Abstract: This article introduces the problem of epistemological cut in the transition from Humanistic to Modem Philosophy with focus on language as discontinuity component in that transition. The argument stresses the common elements between two periods and discusses the language as change of paradigm in the study of nature. Matemathics is both: correspondence with the structure of human mind and a new form of language that makes representation the only possible expression of truth.
DURKHEIM, Émile. Sociologia, Educação e Moral. Porto: Res- Editora, 1984, 398 pp.
Authors: Borges Vera Lúcia Abrão 
Published: November 2022

Marcando o pensamento europeu do séc. XIX e atual, Émile Durkheim (1858-1917), um dos fundadores da Sociologia, fundador e diretor da Revista L'Année Sociologique, está na base da História Social praticada na França - como, por exemplo, em Roger Chartier e em Pierre Bourdieu. É o teórico mais acabado do positivismo e do capitalismo em sua fase imperial, escrevendo uma obra vastíssima, que vai da História e da Filosofia à Educação e à Sociologia, merecendo destaque: A Divisão do Trabalho Social ( 1893), As Regras do Método Sociológico ( 1895 ), O Suicídio ( 1897), As Formas Elementares da Vida Religiosa, bem como outros textos de Educação, de Filosofia e de História.
Embora bem conhecidas do público suas reflexões sobre método sociológico, divisão do trabalho, anomia, suicídio e religião, o mesmo não se pode dizer com relação ao que ele pensa enquanto "pedagogo e teórico da educação e da moral", justamente este que foi o fundador da primeira cátedra de "Educação e Sociologia", na Sorbonne ("Nota da Edição Portuguesa") e que construiu uma teoria da educação que respondia à forma prescrita pela sociedade de então. [...]
Management of COVID-19 During Lockdown and Reopening of Schools: An Experience Case under COVID-19 in Portugal
Authors: Martins António Santos 
Published: November 2022

The COVID-19 pandemic had a disruptive impact on educational institutions, around the world, during the lockdown and after the reopening of the schools. This unprecedented creates big challenges posed to educators, learners and schools to mitigate the effects of the pandemic.

This investigation, supported by a questionnaire, tries to measure the satisfaction of the students, of a Higher-Level Public Education Institution – Guarda Polytechnic (IPG), Portugal, with the measures adopted to control the spread of the COVID-19 pandemic and propose some improvement suggestions.
Although students refer that were satisfied with the arrangement of online classes during the lockdown of the IPG, they recognize that online classes affect negatively the academic performance and prefer face-to-face classes.
In particular, female and older students, students that attend the Master's degrees and students who have been attending the institution for 1 year or less are more satisfied with the overall management of the pandemic.
The Influence of Different Training Load Magnitudes on Sleep Pattern, Perceived Recovery, and Stress Tolerance in Young Soccer Players
Authors: Ferreira Ayrton Bruno de Morais , Ribeiro Bruno Laerte Lopes , Batista Elias dos Santos , Dantas Matheus Peixoto , Mortatti Arnaldo Luis 
Published: November 2022

Abstract
Ferreira, ABdM, Ribeiro, BLL, Batista, EdS, Dantas, MP, and Mortatti, AL. The influence of different training load magnitudes on sleep pattern, perceived recovery, and stress tolerance in young soccer players. J Strength Cond Res XX(X): 000–000, 2022—The aim of this study was to analyze the influence of 3 weeks on sleep parameters, perceived recovery, and stress tolerance in young soccer players using different training load magnitudes. A total of 13 young male soccer athletes (15.9 ± 0.5 years; 68.7 ± 6.1 kg; 170 ± 7 cm) who performed 3 typical training weeks with different workloads were analyzed. The external training load (ETL) was verified by the PlayerLoad method, and the internal training load (ITL) was determined using the session rating of perceived exertion method. Sleep was monitored using a wrist-actigraphy monitor. Sleep variables, including total time in bed (TTB), total sleep time (TST), sleep latency (SL), wake after sleep onset (WASO), and sleep efficiency (SE), were evaluated across all nights of sleep. The recovery status was assessed with the perceived recovery status (PRS) scale, and the stress tolerance was monitored using the “daily analysis of life demands of athletes” questionnaire. There was an increase in sleep time during the week with the highest training load (week 2) (TTB: +35 minutes, TST: +46 minutes, SL: −5 minutes, SE: +3%). There was no difference in the PRS or in the stress tolerance during the evaluation weeks. A very large within-individual correlation was observed between ITL and ETL (r = 0.78) and moderate within-individual correlation between ETL and TST (r = 0.34), between ITL and TST (r = 0.45), and between ITL and SE (r = 0.359). These results showed that there was an increase in TST during a microcycle with intensified loads, without impairing bedtime and resulting in maintenance of the perceived recovery or stress tolerance values.