bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effects of Resistance Training on Physical Fitness and Neuromotor-Cognitive Functions in Adults With Down Syndrome
Authors: Post Emily M. , Kraemer William J. , Kackley Madison L. , Caldwell Lydia K. , Volek Jeff S. , Sanchez Barbara N. , Focht Brian C. , Newton Robert U. , Häkkinen Keijo , Maresh Carl M. 
Published: June 2022

Adults with Down syndrome are an underserved population at high risk for a host of different pathologies from aging and lack of activity.PurposeTo examine the effects of a 10-week resistance training program on measures of motor behavior, cognitive function, mood, and physical fitness.MethodsParticipants (n = 11) were men and women clinically diagnosed with Down syndrome (age: 25.8 ± 6.4 years; height: 151.5 ± 8.3 cm; weight: 67.5 ± 13.0 kg; IQ: 58.3 ± 19.7 units). After familiarization of testing procedures, subjects performed The Arizona Cognitive Test Battery for Down Syndrome, TGMD-2, lower and upper body strength assessments, and body composition via DXA testing, while parental guardians completed cognitive and mood survey assessments (Cognitive Scale for Down Syndrome, Behavioral Rating Inventory of Executive Function, NiSonger Child Behavior Rating Form, Scales of Independent Behavior-Revised, Child Eating Behavior Questionnaire, Social Communication Questionnaire, and Mood and Feelings Questionnaire) at pre and post 10 weeks of periodized resistance training.ResultsSignificant (P ≤ 0.05) improvements in locomotor skills and object control skills were observed post-training. Both locomotor skills (e.g., sprint, gallop, leaping, broad jump) and object control skills (e.g., baseball catch, underhand roll, basketball dribble) were all significantly improved. Facets of cognitive performance significantly improved, specifically executive function and visuospatial working memory capacity, and frontal lobe activity. Mood disturbances significantly decrease. All aspects of physical strength and endurance were improved, i.e., leg press, bench press, sit-ups, push-ups, and chair sit-to-stand post-training. Lean tissue mass was significantly increased post-training.ConclusionThis study dramatically demonstrates that life enhancements for individuals with Down syndrome are achievable with a properly designed resistance training program.
Lessons Learned and Future Actions: Modifying a Stroke Specific Self-Management Program
Authors: Hreha Kimberly , Sonnenfeld Mandi , Na Annalisa , Kitchens Riqiea , Reistetter Timothy A. 
Published: June 2022

BackgroundSelf-management programs have been shown to be effective at providing support to individuals who want to manage chronic health conditions independently. It has been shown that adapting self-management programs for different diagnostic groups, such as stroke, is essential.ObjectiveTo report modifications made during trial implementation, the barriers identified during the delivery of an evidence based, stroke-specific self-management program and minor data (including strategies made) from a small cohort of stroke survivors with multiple chronic conditions.MethodsProspective type III hybrid implementation-effectiveness trial for stroke survivors, with chronic conditions, living in the community, and interested in self-management. Modifications were reported by the following: (1) researcher reflections (2) barriers to implementation and (3) strategies used to address the barrier using the Consolidated Framework for Implementation Research (CFIR) guidelines from field notes.ResultsTwenty-five individuals consented (42% of eligible sample) at the time of acute stroke and five were interested in continuing at the 3-month call. Multiple barriers to implementation were identified, resulting in modifications. For example, before the group sessions began, the COVID-19 pandemic necessitated changes to the intervention delivery. The protocol was modified to an online mode of delivery. In total, there were seven modifications made.ConclusionsThe CFIR was a facilitative tool to report barriers and strategies and emphasized the importance of comprehensive reporting. The modifications to the study were an essential first step to address the research climate and needs of this stroke cohort. Next steps include continued research with a larger cohort to implement effective strategies and answer the clinical question of effectiveness of the adapted and modified intervention.
COVİD-19 Dönemine ait Mavi Kod Uygulama Sonuçlarının Değerlendirilmesi
Authors: KAÇAR Tarık , DEMİRARSLAN Alper Tunga , TOPÇU İsmet , TEZCAN KELEŞ Gönül 
Published: June 2022

Giriş ve Amaç: Mavi Kod, hastanelerde yaşanabilecek ani dolaşım ve solunum durmasında, hastanın en kısa sürede resüsite edilmesini sağlamaya yönelik kullanılan acil durum hastane kodudur. Mavi kod ekibi hastanede kardiyopulmoner resüsitasyon (KPR) konusunda deneyimli ve eğitimli uzman hekim ve hemşirelerden oluşan kalbi yeniden canlandırma müdahale ekibidir.
Gereç ve Yöntemler: Bu çalışmada Mart 2020- Eylül 2021 tarihleri arasında mavi kod çağrısı verilen hastaların verileri retrospektif olarak analiz edildi. Bu süreçte 58 olgu için mavi kod çağrısı verildi, yaş ortalaması 54.78±21.7 yıl olarak bulunmuştur. Pandemi servisleri mavi kod çağrısı verilen birimler arasında üst sıralarda yer almaktadır. Bulgular: Mavi kodlarda uygulanan KPR sonucu 7 hasta (%53) eksitus kabul edilirken, 6 hastada (%47) ritm sağlandıktan sonra yoğun bakım ünitesine nakli sağlanmıştır.
Sonuç: Sonuç olarak; en kısa sürede ve eğitimli ve tecrübeli bir ekiple uygulanan KPR, insan hayatına gösterilen önem ve saygı, yasal sorumluluk ve kaliteli sağlık hizmeti sunumu açısından isabetli ve vazgeçilmez bir standarttır.
ERKEN EVRE MEME KANSERİ HASTALARINDA PATOLOJİK SUBTİPLERE GÖRE D VİTAMİN EKSİKLİĞİ; TEK MERKEZ DENEYİM
Authors: BULUT Gülcan , RIDVANOĞULLARI Melis 
Published: June 2022

Giriş ve Amaç: D vitamini, meme kanseri riskiyle ilişkilendirilmiştir. Bu çalışmanın birinci amacı erken evre meme kanserli hastalarda D vitamin eksikliğini ve meme kanseri patolojik subtiplerine göre D vitamini düzeylerindeki farklılıkları göstermektedir.
Gereç ve Yöntemler: Çalışmaya erken meme kanseri tanısı almış toplam 208 kadın hasta dahil edildi. Patolojik Subtiplere göre (Lüminal; HER2 pozitif; Üçlü negatif; Üçlü pozitif) dört gruba ayrıldı ve meme kanseri alt tiplerinin ortalama D vitamini düzeyleri, VKİ ve dosya verileri SPPS programına girildi.
Bulgular: Ortalama yaş 51.37 +/-10.0 idi. 25(OH)D3 düzeyi ortalama 22.3 +/- 10.6 nmol/L idi. Hastaların % 79.1’inde D vitamini seviyeleri eksikti(
Genotype and Phenotype Analysis Using a Hypertrophic Cardiomyopathy-Associated Gene Panel in Turkish Cardiomyopathy Patients
Authors: GÜN BİLGİÇ Dilek 
Published: June 2022

Objective: Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disorder caused by mutations in sarcomeric proteins and characterized by hypertrophy of the heart muscle.
Materials and Methods: In the present study, 21 patients with HCM and some of their parents were evaluated via next-generation sequencing (NGS) using a targeted panel of 17 genes.
Results: Pathogenic or likely pathogenic variants were detected in six patients in the genes MYH7 (p.R663C, p.A423V), MYBPC3 (p.P955fs*95, p.K301fs*31), TNNT2 (p.R154Q), and TNNI3 (p.R204C).
Conclusion: The genotype-phenotype correlations of these variants were discussed by comparing the clinical findings with the literature. p.R204C variant in the TNNI3 gene was found to be caused restrictive cardiomyopathy for the first time in the literature.
The Change in Expression Levels of RYBP and MDM2 Genes in Colorectal Cancer
Authors: GÜRER Türkan , FARHAN Amina , AYTEKİN Alper 
Published: June 2022

Objective: Colorectal cancer, frequently seen among gastrointestinal cancers, is one of the major causes in mortality and morbidity worldwide. In this study, we aimed to investigate the expression levels of RYBP and MDM2 genes in colorectal cancer. We further examined the possible correlation between RYBP and MDM2 expressions in colorectal cancer and the relationship between the expression of these genes and the clinicopathological features of patients with colorectal cancer.
Materials and Methods: In this study, fresh tumor colon/rectum tissues and the adjacent healthy tissues collected from 43 patients with colorectal cancer during a surgical operation. RYBP and MDM2 mRNA expressions were examined using Real-Time PCR.
Results: In this study results showed that the expression levels of both RYBP and MDM2 were decreased in tumor tissues compared to normal tissues with colorectal cancer patients, but these decreases were not statistically significant (p=0.673 and p=0.721, respectively). Moreover, while there was no correlation between RYBP and MDM2 mRNA expressions in colorectal cancer, no statistically significant relationship was found between the expressions of these genes and clinicopathological data (p>0.05).
Conclusion: Consequently, it can be said that RYBP and MDM2 expressions are not related to colorectal cancer, however, future studies with larger sample groups are needed to validate the results obtained from this study.
Forecast the accuracy of spike and blocking skills in terms of some physical measurements and physical and motor abilities of volleyball players
Authors: Darwesh Nawazad Hussien , Qadir Nihad Ayyub , Sharif Twana Wahbi Ghafoor 
Published: June 2022

Purpose. This study aims to find an equation for accurately predicting the skills of spike skill beating (straight and diagonal), and the blocking skills about specific physical measures physical and kinetic skills of volleyball players. The skill of spike and skill blocking is one of the basic skills in volleyball, whose performance requires high compatibility and balance between physical measurements and physical skills
Material and Methodology. Moreover, monitoring shows that no statistical equation predicts the punch and squeezes talents that hinder the volleyball sector for the age group (14-16). In the youth volleyballers centers in Erbil, the number of players was (75) out of (106) participants (76% of the total population). 25 Players were excluded because they did not complete the test requirements.
Results. The manuscript reached the following results: It was possible to identify the values ​​of some physical measurements and physical and motor abilities affecting the level of accuracy test performance of the skill of spike (straight and diagonal).
And through the logical analysis of the regression of anthropometric indicators and physical and motor abilities
The regression equation for the first indicator was: Ŷ = a + b x
The second indicator is: Ŷ = a + b1 x1 + b2 x2
As for that, the compatibility index is the most contributing variable to the accuracy of the performance of the blocking skill, as its contribution rate was for the first indicator: Ŷ = a + b x
And the second indicator: Ŷ = a + b1 x1 + b2 x2
Conclusions: were a statistically significant correlation between some physical measurements, physical and motor abilities, and the accuracy of the spike skill and the blocking skill (Straight and diagonal) of the research sample. Regression equations were obtained to predict the accuracy of the hit performance (Straight and diagonal) in terms of physical measurements, physical abilities, and kinetics.
Condition of membranes of erythrocytes of peripheral blood of elderly people with chronic tiredness and low level of tolerance to physical load
Authors: Popel Sergii , Меlnic Ivan , Churpiy Іhor , Bejga Przemek , Śliwiński Zbigniew 
Published: June 2022

Purpose: The aim of the work is to study the osmotic stability and morpho-functional features of peripheral blood erythrocytes of patients with chronic fatigue syndrome depending on the level of exercise tolerance and associated risk factors. groups of factors that may be the cause, so the development of measures to eliminate them is an urgent problem today, which requires the development of effective ways to correct chronic fatigue syndrome. It is known that the peripheral part of erythron actively responds to changes that occur in the whole body after the action of various factors, including those factors that lead to chronic fatigue syndrome.
Material and methods of research. The examination was performed on the basis of the Department of Vascular Neurology of the Central Clinical Hospital of Ivano-Frankivsk. The study involved 30 patients aged 55-65 years (mean age 60.6 + 1.2 years), who were divided into 3 groups: 1 gr. included 10 patients with chronic fatigue syndrome and a high level of exercise tolerance. The 2nd group included 10 patients with chronic fatigue syndrome and the average level of exercise tolerance, the composition of 3 gr. included 10 patients with chronic fatigue syndrome associated cardiovascular pathology (angina pectoris, hypertension) and low exercise tolerance (3 gr.).
Results. It is established that chronic fatigue syndrome proceeds in 3 phases and has natural stages of development which are characterized by three groups of etiological factors and the corresponding levels of teletransitivity to physical activity, each of which corresponds to a certain erythrocyte profile and level of osmotic stability of erythrocytes which are offered to use as prognostic and diagnostic characteristics. chronic fatigue syndrome.
Conclusions. The study of the quantitative composition of peripheral blood erythrocytes and hemoglobin, as well as their ratio (color index) in patients with chronic fatigue syndrome on the background of low levels of exercise tolerance revealed a decrease in erythrocytes and hemoglobin by 42% and 25%, respectively, indicating the presence of anemic hypoxia. 2. In conditions of chronic fatigue there is a decrease in osmotic resistance of erythrocytes, as evidenced by a decrease in the number of osmotically stable erythrocytes with a gradual decrease in the concentration of NaCl solution (3.0%; 0.5%; 0.46%; 0.3%). 3. In chronic fatigue there is a deterioration of membranes in peripheral blood erythrocytes, as evidenced by a decrease in their osmotic stability and an increase in the number of irreversibly altered forms of РВЕ, as well as a decrease in peripheral blood erythrocytes, which is closely correlated with decreased tolerance to exercise.
Analisis Pengaruh Temperatur dan Laju Alir Air Pendingin Terhadap Kinerja Kondensor Di PLTU Cirebon Unit 1
Authors: Putra Bima  R , Melkias Alvera , Melkias Alvera , Maridjo  
Published: June 2022

Kondensor adalah alat yang berfungsi mendinginkan atau mengkondensasikan uap keluaran turbin menjadi air. Air pendingin yang masuk ke dalam kondensor memliki nilai temperatur dan laju alir yang bervariasi, hal ini sangat berpengaruh terhadap kinerja kondensor. Kinerja kondensor dapat dilihat dari 2 faktor yaitu Cleanliness Factor dan Condensing Duty. Perhitungan kinerja kondensor menggunakan data aktual pada beban pembangkitan penuh yaitu 660 MW dan hanya diambil beberapa bulan saja, yaitu pada saat beban penuh di tahun 2019. Apabila ditinjau dari pengaruh temperatur air pendingin yang masuk ke dalam kondensor, nilai Cleanliness Factor tertinggi pada bulan Agustus 2019 yaitu 86,16% dan nilai dari Condensing Duty yaitu 721630 Kcal/hr. Sedangkan apabila ditinjau dari pengaruh laju alir air pendingin yang masuk ke dalam kondensor, nilai Cleanliness Factor tertinggi pada bulan Mei 2019 yaitu 83,54% dan nilai dari Condensing Duty yaitu 701673 Kcal/hr. Semakin rendah temperatur air pendingin yang masuk ke kondensor maka panas yang terkandung di dalam uap akan semakin banyak diserap oleh air pendingin. Dan Semakin tinggi nilai laju alir air pendingin yang masuk ke dalam kondensor maka panas yang terbawa oleh air pendingin pun akan semakin banyak, sehingga kinerja kondensor akan baik.
Relationship between Nutritional Status and Urinary Tract Infection in Children
Authors: Hidayati Siti F. , Umboh Valentine , Rondonuwu Shekina H. E. 
Published: June 2022

Abstract: Urinary tract infection (UTI) is one of the most common urinary tract diseases in children of all ages. Risk factors for UTI include age, sex, poor nutrition/nutritional status, uncircumcised boys, personal hygiene, urinary emptying dysfunction, and genitourinary tract abnormalities. It is already known that infection can worsen the nutritional status. This study aimed to evaluate the relationship between nutritional status and UTI in children, the incidence of UTI in children with under nutrition, poor nutrition, and over nutrition, and to compare the incidence of UTI in children with normal nutrition, undernutrition, poor nutrition, and over nutrition. This was a literature review study. The results showed that nutritional status and UTI had a significant relationship. Malnutrition or over nutrition could increase the incidence of UTI. Differences in the incidence of UTI in 12 articles were caused by a variety of factors, such as numbers of boys and girls in the studies, age, environment, and the ways to collect urine samples. In conclusion, there is a significant relationship between nutritional status and the incidence of UTI. Poor nutritional status especially malnutrition and over nutrition could increase the incidence of UTI.Keywords: urinary tract infection (UTI); nutritional status; malnutrition; obesity Abstrak: Infeksi saluran kemih (ISK) merupakan salah satu penyakit saluran kemih yang sering terjadi pada anak dalam semua usia. Faktor risiko ISK antara lain usia, jenis kelamin, gizi buruk/status gizi, anak laki-laki yang belum disirkumsisi, kebersihan diri, disfungsi pengosongan urin, dan abnormalitas saluran genitourinaria. Telah diketahui bahwa infeksi dapat memperburuk status gizi. Penelitian ini bertujuan untuk mengetahui adanya hubungan antara status gizi dan ISK pada anak, angka kejadian ISK pada anak dengan gizi kurang, gizi buruk, dan gizi lebih, serta mengetahui perbandingan kejadian ISK pada anak dengan gizi normal, gizi kurang, gizi buruk, dan gizi lebih. Penelitian ini merupakan suatu literature review. Hasil penelitian mendapatkan adanya hubungan bermakna antara status gizi dan ISK. Malnutrisi maupun gizi lebih dapat meningkatkan angka kejadian ISK. Perbedaan kejadian ISK pada 12 literatur yang diteliti disebabkan karena berbagai faktor, seperti rasio jumlah anak laki-laki dan perempuan dalam penelitian, umur, lingkungan tempat tinggal, dan cara pengambilan sampel urin. Simpulan penelitian ini ialah terdapat hubungan bermakna antara status gizi dan kejadian ISK. Status gizi kurang terutama malnutrisi maupun gizi lebih dapat meningkatkan angka kejadian ISK.Kata kunci: infeksi saluran kemih (ISK); status gizi; malnutrisi; obesitas
PENGARUH VARIASI KONSENTRASI EM4 DAN JENIS LIMBAH KULIT BUAH PADA PEMBUATAN PUPUK ORGANIK CAIR (POC)
Authors: Anita  , Harimbi Setyawati  , Sanny Anjarsari  , Lalu Topan Sulistiyono  , Josephine Vania Wisnurusnadia  
Published: June 2022

Industri makanan berbahan dasar buah-buahan seperti pisang juga nanas ,menghasilkan bahan buangan atau limbah diantaranya berupa kulit dalam jumlah yang banyak. Limbah kulit buah tersebut dapat dimanfaatkan lebih lanjut diantaranya dengan proses daur ulang, menjadi pupuk organik cair (POC). Pupuk Organik Cair (POC) merupakan produk yang berasal dari pembusukan bahan-bahan organik yang berfungsi mengatasi kekurangan unsur hara pada tanaman. Penelitian ini bertujuan untuk mengetahui pengaruh variasi konsentrasi EM4 , sebesar 5%, 10%,15%,20%,25% dan jenis limbah kulit buah diantaranya kulit pisang, kulit nanas, dan campuran kulit pisang dan kulit nanas terhadap kualitas Pupuk Organik Cair (POC) dengan proses Fermentasi. Hasil terbaik untuk kandungan Nitrogen didapatkan pada kulit.nanas sebesar 0,07% dengan konsentrasi EM4 15% , dan untuk hasil kandungan Phospor tertinggi didapat pada kulit .pisang dan kulit nanas sebesar 0,03% dengan konsentrasi EM4 20% , sedangkan kandungan Kalium terbaik didapatkan pada kulit.pisang sebesar 0,38% dengan konsentrasi EM4 20%.
A Motion Flow Guided MicroNet Framework for Micro Expression Recognition
Authors: Verma Monu , Vipparthi Santosh kumar , Singh Girdhari 
Published: June 2022

<p> The micro-expression recognition (MER) has gained high attention in real-world applications: human-computer interaction, depression estimation, virtual reality, etc. However, MER systems still face difficulty in capturing the subtle information with spatial appearance of micro expressions. In this paper, an efficient and robust motion flow-guided MicroNet framework is proposed for MER. The proposed MicroNet consists: motion flow generator (MFGen) and avalanche feature (AFeat) block. The MFGen is introduced to extract the temporal changes at expressive regions by analyzing the motion intensity of pixels among the frames. Further, the AFeat block is designed to capture the spatiotemporal feature using a multi-lateral complementary feature (MCFeat) block. The MCFeat block is proposed to elicit the coarse and deep edge responses from multi-scale receptive fields. Thus, the proposed MicroNet estimates not only momentary variations but also learns affective appearance features of micro expressions. Furthermore, the efficacy of the proposed MicroNet is examined by conducting experiments on two experimental setups using six comprehensive datasets: CASME-I, CASME-II, CAS(ME)2, SAMM, SMIC and COMPOSITE, with two validation schemes: leave-one-subject-out and cross-domain to demonstrate the generalization capacity and robustness of the proposed framework. Also, eight ablation experiments have been executed to validate each module’s role in the MicroNet framework.</p>
Paradigms of US global strategy — concepts globalization and global instability
Authors: Senchenko Mykola 
Published: June 2022

Analyzing the processes and events taking place in the world today, one gets the strong impression that the Washington "sages" — the main directors of modern world development — have decided to abandon the unsuccessful and boring play in order to stage a new one.
It is about the obsolescence of the concept of globalization, so actively discussed in the recent past, and its replacement by the concept of global instability, which is in fact a return to Hegel's dialectic, which states: "all historical events are the result of conflict between opposing forces" [1].
It is the antagonistic contradictions that have led to the strengthening of American dominance in the world as a result of the shaking of stable political structures, the creation of zones of numerous conflicts and world governance through the interaction of opposites in which conflicting forces are irreconcilable. This is achieved by manipulating opposing political forces.