bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhanced Oil Recovery Using Polyaniline‐Sodium Dodecyl Sulfate‐Sodium Hydroxide Flooding‡
Authors: Rishi Lomas , Mandal Monisha Mridha 
Published: January 2022

AbstractThe possibility of using polyaniline (PANI), sodium dodecyl sulfate (SDS) surfactant, sodium hydroxide (NaOH), and their combinations in the enhanced oil recovery process were evaluated with a STARS computer modelling group simulator. The effect of the addition of polymers, such as hydrolyzed polyacrylamide and PANI, surfactant, alkali, and temperature was investigated. Oil saturation contours showed that the residual oil remaining in the oil field was minimum when NaOH‐SDS‐PANI was injected with water. In the case of polymer flooding, the oil recovery increased with higher polymer concentration. The performance of alkali‐surfactant‐polymer flooding indicated that the addition of polymers, surfactants, and alkalis in water improved the oil productivity. PANI was found to be efficient in the recovery of oil especially at higher temperatures.
Heat Exchanger Network Design Using MATLAB
Authors: Tewari Kshitij , Shukla Sakshi , Arya Raj Kumar 
Published: January 2022

AbstractA generalized MATLAB scheme is developed to analyze and design heat exchanger networks (HENs) in process industries. This scheme has been checked for various industrial problems from the literature. The results produced by the proposed scheme are in exact agreement with the literature. The proposed scheme is user‐friendly and less time‐consuming. It will be helpful for industry persons, process engineers, and budding chemical engineers, involved in modeling and simulation studies in order to minimize the energy requirements of industries as well as for academic purposes. The proposed scheme just needs a MATLAB package which is easily available and cheaper than other commercially available heat exchanger network design packages.
Review on Electrochemical Sensing of Triclosan using Nanostructured Semiconductor Materials
Authors: Sri Vidhya R. , Shwetharani R. , Mohammed Jalalah , Mabkhoot Alsaiari , Balakrishna R. Geetha , Harraz Farid A. 
Published: January 2022

AbstractTriclosan (TCS) is an antifungal and antimicrobic component used in various cosmetic, healthcare, and personal care products; therefore, many people are exposed to this compound. Literature and related studies have shown inflammatory skin conditions and endocrine disruption after exposure to TCS. Low concentrations of TCS released into environmental wastewater and soil eventually increase the toxicity. Hence, the detection and sensing of TCS is an important process. Nanostructured semiconductor materials are widely used for the selective and sensitive sensing of TCS because of their high accuracy, wide linear range, and high conductivity. This Review describes the progress made in the use of nanostructured particles such as metal oxides and metal oxide nanocomposite, multiwalled carbon nanotubes (MWCNTs), carbon nanodots (CNDs), graphene, molecular imprinted polymers (MIPs), organic polymers, polymer nanocomposite, quantum dots (QDs), gold nanoparticles, silver nanoparticles, and other nanoparticles as electrode active materials for the electrochemical sensing of TCS in environmental samples.
Influence of the Flexibility of Nickel PCP‐Pincer Complexes on C−H and P−C Bond Activation and Ethylene Reactivity: A Combined Experimental and Theoretical Investigation
Authors: He Fengkai , Gourlaouen Christophe , Pang Huan , Braunstein Pierre 
Published: January 2022

AbstractUsing a pincer platform based on a bridgehead NHC donor with functional side arms, the combined effect of increased flexibility in six‐membered pyrimidine‐type heterocycles compared to the more often studied five‐membered imidazole, and rigidity of phosphane side arms was examined. The unique features observed include: 1) the reaction of the azolium Csp2−H bond with [Ni(cod)2] affording a carbanionic ligand in [NiCl(PCsp3HP)] (8) rather than a carbene; 2) its transformation into the NHC, hydrido complex [NiH(PCNHCP)]PF6 (9) upon halide abstraction; 3) ethylene insertion into the Ni−H bond of the latter and ethyl migration to the N−C−N carbon atom of the heterocycle in [Ni(PCEtP)]PF6 (10); and 4) an unprecedented C−P bond activation transforming the P−CNHC−P pincer ligand of 8 in a C−CNHC−P pincer and a terminal phosphanido ligand in [Ni(PPh2)(CCNHCP)] (15). The data are supported by nine crystal structure determinations and theoretical calculations provided insights into the mechanisms of these transformations, which are relevant to stoichiometric and catalytic steps of general interest.
In Situ Synthesis of Phenoxazine Dyes in Water: Application for “Turn‐On” Fluorogenic and Chromogenic Detection of Nitric Oxide**
Authors: Jenni Sébastien , Renault Kévin , Dejouy Garance , Debieu Sylvain , Laly Myriam , Romieu Anthony 
Published: January 2022

AbstractThe synthesis of phenoxazine dyes was revisited in order to access these fluorescent N,O‐heterocycles under mild conditions. The combined sequential use of nitrosonium tetrafluoroborate (NOBF4) and triphenylphosphine enables the facile conversion of bis(3‐dimethylaminophenyl) ether into the methyl analogue of popular laser dye oxazine 1. The ability of nitrosonium cation (NO+) to initiate the domino reaction resulting in π‐conjugated phenoxazine molecules under neutral conditions, then led us to explore the feasibility of expanding it in aqueous media. Thus, we explored the use of reactive signaling molecule nitric oxide (NO) as a biological trigger of phenoxazine synthesis in water. The implementation of a robust analytical methodology based on fluorescence assays and HPLC‐fluorescence/‐MS analyses, have enabled us to demonstrate the viability of this novel fluorogenic reaction‐based process to selectively yield an intense “OFF‐ON” response in the near‐infrared (NIR‐I) spectral region. This study is an important step towards the popularization of the concept of “covalent assembly” in the fields of optical sensing, bioimaging and molecular theranostics.
Reversible Photoluminescence Control of Azobenzene Crystals by Light and Heat Stimulation
Authors: Yamauchi Mitsuaki , Okaji Miho , Aratani Naoki , Yamada Hiroko , Masuo Sadahiro 
Published: January 2022

AbstractStimulus‐responsive photoluminescence (PL) materials have attracted attention because of their broad applicability in recording, switching and sensing devices. However, the development of PL materials controllable by a light stimulus remains a challenging task. Here, we demonstrate novel organic crystals of a naphthalene‐functionalized azobenzene derivative (NA) that exhibit reversible PL properties upon light and heat stimulation. The azobenzene derivative exhibits aggregation‐induced emission (AIE) in the orange PL region upon crystallization. Upon photoirradiation, the crystal transforms into an aggregate with low crystallinity via trans‐to‐cis photoisomerization. Therefore, the PL color changes from orange to yellow when the orderly aggregated NAs are converted into randomly aggregated NAs. Furthermore, the original orange PL can be recovered upon heating and cooling the photoirradiated crystal as a result of cis‐to‐trans thermal back‐isomerization.
A Perfusion Bioreactor Model of Tumor‐Induced Bone Disease Using Human Cells
Authors: Lowen Gregory B. , Vanderburgh Joseph P. , Florian David , Scott Taylor , Sterling Julie A. Rhoades , Guelcher Scott A. 
Published: January 2022

AbstractAdvanced solid tumors often metastasize to bone. Once established in bone, these tumors can induce bone destruction resulting in decreased quality of life and increased mortality. Neither 2D in vitro models nor 3D animal models sufficiently recapitulate the human bone‐tumor microenvironment needed to fully understand the complexities of bone metastasis, highlighting the need for new models. A 3D in vitro humanized model of tumor‐induced bone disease was developed by dynamically culturing human osteoblast, osteoclast, and metastatic cancer cells together within tissue‐engineered bone constructs. Cell‐mediated resorption can be observed by micro‐computed tomography and can be quantified by change in mass. Taken together, these data can be used to investigate whether the metastatic cancer cells included in the model have the potential to drive osteoclastogenesis and cell‐mediated resorption in vitro. © 2022 Wiley Periodicals LLC.Basic Protocol 1: Fabricating bone‐like scaffoldsBasic Protocol 2: Preparing cells for the humanized model of TIBDBasic Protocol 3: Crafting a 3D in vitro humanized model of TIBD
Dynamic resource allocation in cloud infrastructure using ant lion‐based auto‐regression model
Authors: Kavitha Jaggannagari , Thirupathi Rao Komati 
Published: January 2022

SummaryCloud computing provides a quick, simple, and gainful means for configuring and assigning the resources for a web‐based appliance, like medical records systems, smart grid applications, and security management infrastructures. The optimization of resource allocation in the cloud is a major task for meeting customer demands and maximizing profit. This paper devises an optimization method for allocating resources in cloud infrastructures. The main contribution is to provide a framework for allocating the available resource to the deserving tasks. Here, the dynamic resource allocation is performed to allocate the resources dynamically as requested by users without affecting the system performance. Here, the ant lion‐based auto‐regressive optimization (ALAO) strategy is employed to allocate the cloud resources. ALAO is designed by integrating Ant Lion Optimizer (ALO) in auto‐regression model for further enhancing the allocation of resources, and a new fitness function is adapted, which considers certain parameters, such as cost, speed, and load. The results proved that the proposed ALAO algorithm attained enhanced performance with a maximal profit of 0.153, a minimum load of 0.028, and a minimal task assignment cost of 0.094.
Differential diagnosis of lipoma and atypical lipomatous tumor/well‐differentiated liposarcoma by cytological analysis
Authors: Sugiyama Kana , Washimi Kota , Sato Shinya , Hiruma Toru , Sakai Mai , Okubo Yoichiro , Miyagi Yohei , Yokose Tomoyuki 
Published: January 2022

AbstractBackgroundAdipocytic tumors are the most common soft tissue tumors, with lipomas and atypical lipomatous tumor/well‐differentiated liposarcomas (ALT/WDL), which comprise most cases. Preoperative differential diagnosis of lipoma or ALT/WDL can provide important information for decisions regarding treatment. We evaluated the cytological findings of 20 cases of lipoma and ALT/WDL.MethodsFluorescence in situ hybridization (FISH) was performed on formalin‐fixed paraffin‐embedded specimens (FFPE) to examine mouse double minute 2 homolog (MDM2) amplification in all cases. Tissue samples were collected from the center of the surgical materials, stained with Pap, and evaluated for 12 cytological parameters by six cytotechnologists.ResultsThe findings regarding large atypical cells, multinucleated cells, and nuclear pleomorphism were highly concordant among the cytotechnologists and were associated with MDM2 amplification. Large atypical cells, considered a highly specific feature of ALT/WDL, were not observed in lipoma cases. However, the sensitivity of the large atypical cell findings was not high (67%); therefore, comprehensive evaluation of multinucleated cells and pleomorphism is crucial for predicting ALT/WDL diagnosis. FISH of MDM2 on Pap‐stained specimens was performed in four cases. In two, the results were similar to those of MDM2 FISH performed on FFPE sections and were reproducible, whereas in the other two, the signal could not be evaluated because of the strong background coloration.ConclusionsCytology specimens may be useful for the preoperative diagnosis of adipocytic tumors, particularly if the FISH conditions for Pap‐stained specimens and the detection accuracy of MDM2 amplification can be improved.
Ganglioneuroma on fine needle aspiration cytology: Case series and review of the literature
Authors: Fang Camila , Pizzillo Isabella , Shi Yan , Sun Wei , Brandler Tamar C. 
Published: January 2022

AbstractWe report two cases of an uncommon benign lesion, retroperitoneal ganglioneuroma, first diagnosed on fine needle aspiration (FNA) cytology. Our first case presented with nausea, constipation, vomiting, and neutropenia after three cycles of chemotherapy for breast cancer treatment, while our second patient presented with seemingly unprovoked abdominal pain and progressive neuropathy. Both underwent computed tomography (CT) scans, in which a soft tissue mass was found in the retroperitoneal space in each patient. An endoscopic ultrasound guided (EUS) FNA was performed on both patients, and as a result, the masses were diagnosed as retroperitoneal ganglioneuromas. As retroperitoneal ganglioneuromas have low incidence of proliferation, invasive surgery was avoided in favor of routine follow‐up imaging. Cytologically, both masses showed large, scattered ganglion cells with abundant cytoplasm and large nuclei against a background of wavy spindle cells with elongated nuclei. Histologically, both were positive for S‐100. When an EUSFNA is performed and quality material is collected, a diagnosis of retroperitoneal ganglioneuroma may be established, preventing invasive surgery and its accompanying risks in favor of routine follow‐up imaging.
Prognostic value of the MELD‐XI score in patients undergoing cardiac resynchronization therapy
Authors: Saito Yuki , Nakai Toshiko , Ikeya Yukitoshi , Kogawa Rikitake , Otsuka Naoto , Wakamatsu Yuji , Kurokawa Sayaka , Ohkubo Kimie , Nagashima Koichi , Okumura Yasuo 
Published: January 2022

AbstractAimsMulti‐organ dysfunction was recently reported to be a common condition in patients with heart failure (HF). The Model for End‐stage Liver Disease eXcluding International normalized ratio (MELD‐XI) score reflects liver and kidney function. The prognostic relevance of this score has been reported in patients with a variety of cardiovascular diseases who are undergoing interventional therapies. However, the relationship between the severity of hepatorenal dysfunction assessed by the MELD‐XI score and the long‐term clinical outcomes of HF patients receiving cardiac resynchronization therapy (CRT) has not been evaluated.Methods and resultsClinical records of 283 patients who underwent CRT implantation between March 2003 and October 2020 were retrospectively evaluated (mean age 67 ± 12, 22.6% female). Blood samples were collected before CRT implantation. Patients were divided into three groups based on tertiles of the MELD‐XI score: first tertile (MELD‐XI = 9.44, n = 95), second tertile (9.44 < MELD‐XI < 13.4, n = 94), and third tertile (MELD‐XI ≥ 13.4, n = 94). The primary endpoint was all‐cause mortality. Compared with the other groups, the third tertile group exhibited significantly older age, higher prevalence of diabetes mellitus and hypertension, lower haemoglobin level, and higher N‐terminal pro‐brain natriuretic peptide level (all P < 0.05). The functional CRT response rate was also significantly lower in the third tertile group (P = 0.011). During a median follow‐up of 30 months (inter‐quartile range, 9–67), 105 patients (37.1%) died. Kaplan–Meier analysis revealed that patients with a higher MELD‐XI score had a greater risk of all‐cause mortality (log‐rank test: P < 0.001). Even after adjustment for clinically relevant factors and a conventional risk score, the MELD‐XI score was still associated with mortality (adjusted hazard ratio: 1.04, 95% confidence interval: 1.00–1.07, P = 0.014, and adjusted hazard ratio: 1.04, 95% confidence interval: 1.01–1.09, P = 0.005, respectively). A higher MELD‐XI score was associated with a greater risk of all‐cause mortality than a lower MELD‐XI score regardless of whether a pacemaker or defibrillator was implanted (log‐rank test: P = 0.010 and P < 0.001, respectively).ConclusionsImpaired hepatorenal function assessed by the MELD‐XI score was associated with older age, higher prevalence of multiple co‐morbidities, severity of HF, lower CRT response rates, and subsequent all‐cause mortality in HF patients undergoing CRT implantation. These results suggest that the MELD‐XI score can provide additional prognostic information and may be useful for improving risk stratification in this population.
Prediction of a Tensile Force‐Induced Structural Phase Transition from β‐Ti3O5 to λ‐Ti3O5 by Molecular Dynamic Simulations
Authors: Takeda Takuma , Ohkoshi Shin‐ichi 
Published: January 2022

AbstractLambda trititanium pentoxide (λ‐Ti3O5) exhibits both a light‐induced phase transition and a pressure‐induced phase transition to beta trititanium pentoxide (β‐Ti3O5). Here, we investigate the possibility of a phase transition from β‐Ti3O5 to λ‐Ti3O5 by tensile force. Molecular dynamic simulations predict a tensile force‐induced phase transition from β‐Ti3O5 to λ‐Ti3O5 when the tensile force (p) is applied in the c‐axis direction. At p=4.2 GPa, the lattice constant of β‐Ti3O5 in the c‐axis direction abruptly increases, whereas that in the b‐axis direction decreases. Additionally, the β angle drops from 91.7° to 88.5°. We also evaluate the atomic arrangements of the Ti(3), O(4), and O(3) sites. The distance between Ti(3) and O(3) increases, while that between Ti(3) and O(4) decreases, coinciding with the expansion of the c‐axis lattice constant.
Substituted Malonic Acid Half Oxyesters (SMAHOs): Green Nucleophiles for Organic Synthesis
Authors: Xavier Tania , Condon Sylvie , Pichon Christophe , Le Gall Erwan , Presset Marc 
Published: January 2022

AbstractSubstituted malonic acid half‐oxyesters (SMAHOs) constitute an original family of malonic acid derivatives. They could be mostly used as pro‐nucleophiles through decarboxylative processes, making them enolate equivalents for the elaboration of greener methodologies. In addition to the native ester function, the presence of a substituent on the malonic position affords additional opportunities for structural diversification. These reagents are particularly well‐suited for the development of organocatalyzed processes, which has recently led to olefination and addition reactions as relevant synthetic routes to elaborated structures under mild conditions.
Quick cooperative spectrum sensing in cognitive unmanned aerial vehicles networks
Authors: Wu Jun , Zhang Jia 
Published: January 2022

AbstractIn cognitive unmanned aerial vehicles (UAVs) networks (CUAVNs), cooperative spectrum sensing (CSS) has been recognized as a key technology to enable UAVs to detect spectrum holes and opportunistically access primary licensed spectrum band without harmful interference. Considering that the location flexibility of flying UAV spectrum sensors makes the collaborative working mode of multiple UAVs difficult to achieve, this article establishes an easy‐to‐implement intraframe CSS mode by considering the cooperation within the microsensing time slots of a single UAV. On the basis of this, we adopt sequential probability ratio test (SPRT) as the fusion criterion of sensing decisions from microsensing slots to implement quick CSS for multiple channels under the sensing delay limit and make an investigation the achievable throughput of truncated‐SPRT for CUAVNs. Due to the uncertainty of the sensing decision number required in SPRT, we further propose a soft truncation (ST) way to terminate SPRT process and further evaluate the global CSS performance. At last, numerical simulation results show that the CSS efficiency of the proposed intraframe CSS outperforms that of the traditional interframe CSS, and the performance of ST‐SPRT is also better than hard truncation (HT)‐SPRT, in terms of the detection performance and throughput, especially in the multichannel spectrum sensing scenario.
Adaptive divergence and the evolution of hybrid trait mismatch in threespine stickleback
Authors: Chhina Avneet K. , Thompson Ken A. , Schluter Dolph 
Published: January 2022

AbstractSelection against mismatched traits in hybrids is the phenotypic analogue of intrinsic hybrid incompatibilities. Mismatch occurs when hybrids resemble one parent population for some phenotypic traits and the other parent population for other traits, and is caused by dominance in opposing directions or from segregation of alleles in recombinant hybrids. In this study, we used threespine stickleback fish (Gasterosteus aculeatus L.) to test the theoretical prediction that trait mismatch in hybrids should increase with the magnitude of phenotypic divergence between parent populations. We measured morphological traits in parents and hybrids in crosses between a marine population representing the ancestral form and twelve freshwater populations that have diverged from this ancestral state to varying degrees according to their environments. We found that trait mismatch was greater in more divergent crosses for both F1 and F2 hybrids. In the F1, the divergence–mismatch relationship was caused by traits having dominance in different directions, whereas it was caused by increasing segregating phenotypic variation in the F2. Our results imply that extrinsic hybrid incompatibilities accumulate as phenotypic divergence proceeds.
Study on volatile aroma compounds in donkey broths of different stewing time
Authors: Wang Shuqi , Liu Haoyue , Xie Tian , Zhang Ning , Sun Jie , Chen Haitao , Sun Baoguo 
Published: January 2022

AbstractDonkey broth has a unique aroma and is affected by cooking time. Five donkey broth samples of different stewing time were prepared. The volatile components were extracted by solvent‐assisted flavor evaporation (SAFE) and analyzed by gas chromatography‐mass spectroscopy (GC‐MS). According to the result, a total of 45 volatile aroma compounds were identified in five donkey broths (stewing time of 0 min, 1, 2, 3 and 4 h respectively). In terms of gas chromatography‐olfactometry (GC‐O) analysis, aroma extraction dilution analysis (AEDA) and calculating odor activity values (OAVs), respective 26 and 15 aroma active compounds were pointed out significantly in five donkey broths. Twelve odorants including 2‐methyl pentanal, 3‐hydroxyl‐2‐butanone, hexanal, dimethyl trisulfide, nonanal, 3‐(Methylthio)propanal, 2‐ethyl‐1‐hexanol, benzaldehyde, 4‐methoxyallylbenzene, (E,E)‐2,4‐nonadienal, delta‐hexalactone and octanoic acid were characterized as the common aroma active compounds existed in donkey broths with different stewing time. Principal component analysis (PCA) and sensory evaluation results characterized the difference of aroma profiles for the five different donkey broths, which showed that the duration of the stewing time had an important effect on the general flavor of donkey broth.
COSMO‐RS as an effective tool for predicting the physicochemical properties of fragrance raw materials
Authors: Dupeux Tristan , Gaudin Théophile , Marteau‐Roussy Clémentine , Aubry Jean‐Marie , Nardello‐Rataj Véronique 
Published: January 2022

AbstractA predictive tool called COSMO‐RS, Conductor‐Like Screening Model for Real Solvents, based on quantum chemistry, dielectric continuum models, electrostatics surface interactions, and statistical thermodynamics, has been used to predict five key physicochemical properties of raw materials used in perfumery industries. The prediction of boiling point (BP), octanol‐water partition coefficient (logP), vapor pressure (VP), water solubility (WS), and Henry's law constant (HLC) of fragrance molecules has been validated with a reference data set of 166 organic compounds. Knowing these properties for a fragrance molecule is essential and being able to predict them precisely can be particularly useful in the development of new molecules or in the replacement of controversial molecules regarding safety issues without compromising the overall hedonic accord. Finally, mapping the vapor pressureversusthe Henry's law constant and the octanol‐water partition coefficient consistently predicts the note class of the molecules useful for release comparison of captives.