bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Anti-Platelet Therapy on Peri-Operative Blood Loss in Patients Undergoing Off-Pump Coronary Artery Bypass Grafting
Authors: Kapoor Samir , Singh Gurmeet , Arya Rajesh Chand , Singh Vikrampal , Garg Arun , Ralhan Sarju , Gupta Vivek Kumar , Mohan Bishav , Wander Gurpreet Singh , Gupta Rajiv Kumar 
Published: April 2022

Purpose:
The purpose of this study was to review the effect of the pre-operative use of clopidogrel and aspirin on peri-operative bleeding, blood product transfusion, and resource utilization after coronary artery bypass grafting (CABG).

Materials and Methods:
A total of 1200 patients who underwent off-pump CABG (OPCABG) between 2010 and 2012 were retrospectively studied. Patients were divided into three groups: group 1: discontinued aspirin and clopidogrel 6 days prior to surgery (n = 468), group 2: discontinued both drugs 3 to 5 days prior to surgery (n = 621), and group 3: discontinued both drugs 2 days prior to surgery (n = 111). The bleeding pattern and blood product transfusion were studied and compared between the groups. Patients having history of other drugs affecting the coagulation profile, other organ dysfunction, on-pump CABG, and the combined procedure were excluded from the study.

Results:
Group 2 patients had a higher rate of bleeding and a reduced mean value of hemoglobin (Hb) as compared to other groups. The same results were seen in blood and blood product transfusion. Patients of group 2 and group 3 were associated with higher blood loss in terms of drainage at 12 and 24 hours. Post-operatively, this was statistically significant. Re-exploration was statisitically significant in group 3 patients (9.01%) than in group 2 (2.58%) and group 1 (1.07%) patients.

Conclusion:
The pre-operative use of clopidogrel and aspirin in patients undergoing OPCABG showed limited clinical benefits; however, its use significantly increased the risk of bleeding and blood transfusion, thus increasing morbidity and resource utilization. Hence, clopidogrel and aspirin should be stopped at least 6 days prior to surgery.
Thyroid carcinoma as a dural mass
Authors: Narayanan Sivaranjini , Hiryur Srilakshmi P. 
Published: April 2022

Context:
Distant metastasis is a rare, primary manifestation of follicular carcinoma of the thyroid.

Case Report:
We report a case of a 72-year-old woman presenting with a solid mass located in the left parieto-occipital region. The 3D computed tomography (CT) showed a large solid mass supplied by branches of the external carotid artery. After magnetic resonance imaging, a probable diagnosis of meningioma was made. The patient underwent surgery where a soft mass invading the superior sagittal sinus was encountered and resected. Histological examination revealed a thyroid follicular neoplasm with positive staining for thyroglobulin and thyroid transcription factor I on immunohistochemical analysis. Postoperatively, levels of thyroid hormones were normal. Subsequent ultrasonogram revealed a nodule in the thyroid gland, which on fine needle aspiration cytology was diagnosed as a follicular neoplasm. Treatment was planned for the thyroid gland, the patient receiving chemotherapy including sorafenib.

Conclusions:
The present case emphasizes that although they are uncommon, dural metastasis can be mistaken for meningiomas. Confirmation of diagnosis as meningioma should be established only after the histopathological analysis. Thyroid follicular carcinoma should be included in the differential diagnosis in cases of extrinsic tumoral lesions.
Ayurveda multimodal treatment approach for the management of generalized plaque psoriasis
Authors: Mehere Nikhil A. , Makwana Sarika M. , Chaudhary Swapnil Y. , Bedarkar Prashant , Patgiri B J 
Published: April 2022

Background:
Plaque psoriasis typically presents with large, oval-circular plaques over the scalp, trunk, and extensor body surface. In Ayurveda, all the skin diseases depict under the heading “Kustha” (skin diseases). Among them, “Ekakustha” (psoriasis) is further explained under the title “Kshudra Kustha” (minor skin diseases). It is characterized by the hyperproliferation of the epidermal cells resulting in plaque formation over the lesions and may get severe and progress into the pustular subtype.

Aim:
Plaque psoriasis is compared with Ekakushtha in Ayurveda because of its resemblance to disease condition that is described in the Ayurveda classics. The aim of this study was to treat a patient with Ayurveda multimodal treatment approach.

Materials and Methods:
We, herein, reported a case of a woman aged 29 years complaining about reddish lesions over the scalp, peripheral area of eyes, trunk, back, and upper and lower extremities with intense pruritus since the last 8 months. Itching leads to scaling and trickling of blood from lesions. The patient was diagnosed with generalized plaque psoriasis. This case was treated by internal as well as topical medicament with the cessation of known etiological factors.

Results:
A significant reduction in the symptoms within 98 days of treatment without reported relapse manifestation of previous symptoms. The scores of 18, 10, and 2 were observed before treatment, after treatment, and after follow-up period, respectively, on the symptomatic relief in signs and symptoms of Ekakushtha. The Psoriasis Area Severity Index (PASI) score was adopted as the assessment of severity of case. The PASI score is zero after the treatment and 12.2 before the treatment. The Ayurveda multimodal treatment approach gives miraculous result in this type of complex nature of psoriasis disease.
Prevalence of Chagas Disease and Associated Factors in an Endemic Area of Northeastern Argentina
Authors: Baeck Inés María , Mando Pablo , Virasoro Belén María , Martinez Alfredo , Zarate Soledad , Valentini Ricardo , Lopez Saubidet Ignacio 
Published: April 2022

ABSTRACT.
Chagas disease caused by Trypanosoma cruzi, remains one of the leading public health problems in Latin America. The number of infections in nonendemic countries continues to rise as a consequence of migratory flows. Updated information on prevalence, especially in treatable stages, together with vector eradication programs are key factors in an attempt to control the disease. We aim to estimate the prevalence of T. cruzi infection in an endemic area of Argentina and to describe epidemiological and clinical factors related to the disease. This is a cross-sectional study in an endemic rural area of Argentina. Our target population was people between 10 and 20 years of age, collecting demographic, clinical, and electrocardiographic data and seroprevalence against T. cruzi. We included 460 subjects; 76.7% did not have drinking water; 49.3% reported the presence of Triatoma infestans at home; 79.1% had pets or birds; 72.6% lived close to a chicken coop; 24.6% lived in adobe houses; 27.8% lived in overcrowded conditions. Seroprevalence was 9.33%. In the multivariate analysis, the presence of Triatoma infestans at home (OR 2.08, P = 0.03) had an association with seropositivity. No relevant findings indicating acute or chronic organ involvement were detected. We found no correlation of right bundle branch block (RBBB) and Chagas disease in our population. None of the infected patients were previously aware of their condition, highlighting the importance of active surveillance to detect infection in a potentially treatable stage, especially in areas with difficult access to health programs.
Empirical analysis of amylolytic and proteolytic activities of microbial isolates recovered from deteriorating painted wall surfaces in Lagos Nigeria
Authors: Obidi Olayide Folashade , Awe Olushina Olawale , Igwo-Ezikpe Miriam Nwanna , Okekunjo Folake Okedayo 
Published: April 2022

The biodeterioration of painted walls have been associated with several biological mechanisms such as organic acid production and enzymatic activity of microorganisms amongst other factors. Therefore, this study aims to reveal the involvement of amylases and proteases from indigenous microbes on biodeteriorating painted walls. Microbial strains isolated from biodeteriorating painted walls of selected buildings in Lagos, Nigeria and previously characterized as belonging to the genera Pseudomonas, Candida, Fusarium, Aspergillus, Cerrena and Meyerozyma were used in this study. Amylolytic and proteolytic activities at varying conditions of temperature, pH, incubation time and substrate concentrations were tested. To bridge the knowledge gaps regarding statistical quantification of enzymatic mechanisms in biodeterioration, the Wilcoxon signed rank sum test was used to test the hypothesis that amylolytic/proteolytic activities are equal at all conditions tested. The conditions for optimal activity were observed to be 24h, 37oC, pH 2 and 0.01% substrate concentration and 48h, 25oC, pH 2, and 1% substrate concentration for amylase and protease respectively. Wilcoxon signed rank test revealed that amylolytic and proteolytic activities do not impact aesthetics on painted walls equally at all environmental conditions considered.
Assessment of knowledge and awareness regarding opioid overdose and toxicity among a sample of healthcare providers
Authors: Alotaibi Fahad Marzouq , Zaitoun Mohammed Fathullah , Alotabi Rayid Shabeeb , Alhadi Mohammed Saeed A. , AlShahrani Amani Mohammed , Almoeed Alyah Abdullah , AlNasser Marzouq Saeed , Bamagous Ghazi 
Published: April 2022

Background: Knowledge and attitudes of healthcare providers regarding opioid toxicity are significant concerns. Objective: Investigate the knowledge, attitudes, awareness, and comfort level regarding overdosing among a sample of healthcare providers working at the Armed Forces Hospital Southern Region (AFHSR). Methods: Anonymous surveys were administered to AFHSR staff to assess attitude, knowledge, comfort level, and fear of consequences using a 5-point scale. Participants were AFHSR primary care physicians/internists, surgeons, physician assistants/advanced practice registered nurses, and pharmacists. Results: Healthcare providers demonstrated a lack of knowledge, awareness, and fear of the consequences associated with opioid use, overdose, and the indications and administration of naloxone. This study’s findings indicate that healthcare providers are hesitant to engage in discussions with patients about preventative measures for opioid overdose, with the majority believing that doing so will make no difference in preventing opioid overdose incidence. Additionally, a distinct difference in knowledge and perceptions of opioid abuse and toxicity was found between nurses and physicians. Further, the findings indicate a difference in knowledge and awareness regarding opioid overdose and toxicity between nurses and pharmacists.
Pencatatan Perkawinan Berdasarkan Penerapan Objektifikasi Hukum Perkawinan Islam di Indonesia
Authors: Nasrudin Nasrudin , Mohamad Kasim Nur , Margareth Tijow Lusi 
Published: April 2022

Perkawinan yang tidak tercatat banyak menimbulkan dampak buruk bagi kelangsungan rumah tangga walaupun sudah di terbitkan aturan tentang Isbat nikah. Akibat hukumnya bagi perkawinan yang tidak memiliki akte nikah, secara yuridis suami/istri serta anak yang dilahirkan tidak dapat melakukan tindakan hukum keperdataan berkaitan dengan rumah tangganya. Penelitian ini bertujuan untuk mengetahui dan menganalisis Pencatatan Perkawinan Berdasarkan Penerapan Objektifikasi Hukum Perkawinan Islam di Indonesia. Metode penelitian yang digunakan yakni yuridis normatif dengan pendekatan undang – undang dan pendekatan kasus. Sumber bahan hukum adalah sumber bahan hukum utama (primer) dan sumber bahan hukum pelengkap (sekunder), serta data yang diperoleh melalui penelitian secara kualitatif, kemudian disajikan secara deskriptif yaitu menggambarkan, menguraikan, dan menjelaskan sesuai dengan permasalahan yang erat kaitannya dengan penelitian ini. Hasil penelitian ini menunjukkan bahwa perkawinan yang tidak tercatat berimplikasi pada status hukum perkawinan dan status hukum anak serta sistem kewarisan yang menimbulkan ketidakpastian hukum
Upaya Meningkatkan Prestasi Belajar Bahasa Inggris dengan Menerapkan Metode Kooperatif Model Jigsaw pada Siswa Kelas X SMALB-A Citeureup Cimahi
Authors: Barus Danias 
Published: April 2022

Kekhawatiran bahwa semangat siswa dalam mengembangkan diri secara individual bisa terancam dalam penggunaan metode kerja kelompok bisa dimengerti karena dalam penugasan kelompok yang dilakukan secara sembarangan, siswa bukannya belajar secara maksimal, melainkan belajar mendominasi ataupun melempar tanggung jawab. Metode pembelajaran gotong royong distruktur sedemikian rupa sehingga masing-masing anggota dalam satu kelompok melaksanakan tanggung jawab pribadinya karena ada sistem akuntabilitas individu. Siswa tidak bisa begitu saja membonceng jerih payah rekannya dan usaha setiap siswa akan dihargai sesuai dengan poin-poin perbaikannya. Permasalahan yang ingin dikaji dalam dalam penelitian tindakan ini adalah: (a) Apakah pembelajaran kooperatif model Jigsaw berpengaruh terhadap hasil belajar Bahasa Inggris? (b) Seberapa tinggi tingkat penguasaan materi pelajaran Bahasa Inggris dengan diterapkannya metode pembelajaran kooperatif model Jigsaw? Sedangkan tujuan dari penelitian ini adalah: (a) Untuk mengungkap pengaruh pembelajaran kooperatif model Jigsaw terhadap hasil belajar Bahasa Inggris. (b) Ingin mengetahui seberapa jauh pemahaman dan penguasaan mata pelajaran Bahasa Inggris setelah diterapkannya pembelajaran kooperatif model Jigsaw pada siswa kelas x SMALB-A Citeureup Cimahi. Penelitian ini menggunakan penelitian tindakan (action research) sebanyak tiga putaran. Setiap putaran terdiri dari empat tahap yaitu: rancangan, kegiatan dan pengamatan, refleksi, dan revisi. Sasaran penelitian ini adalah siswa kelas x SMALB-A. Data yang diperoleh berupa hasil tes formatif, lembar observasi kegiatan belajar mengajar. Dari hasil analisis didapatkan bahwa prestasi belajar siswa mengalami peningkatan dari siklus I sampai siklus III yaitu, siklus I (66,66%), siklus II (77,77%), siklus III (88,88%). Simpulan dari penelitian ini adalah pembelajaran kooperatif model Jigsaw dapat berpengaruh positif terhadap motivasi belajar siswa kelas x SMALB-A Citeureup Cimahi. serta model pembelajaran ini dapat digunakan sebagai salah satu alternatif pembelajaran Bahasa Inggris.
Praktik Agen dan Struktur : Pemberdayaan Dana Zakat dalam Upaya Meningkatkan Kualitas Pendidikan Studi Kasus Lembaga Amil Zakat Madhani Human Care (LAZ MHC) Kota Dumai
Authors: Sahrani Nita , Daulay Harmona , Elida Linda , Ismail Rizabuana , Sitorus Henry 
Published: April 2022

Tujuan penelitian ini adalah untuk mengetahui praktik agen dan struktur pada Lembaga Amil ZakatMadhani Human Care (LAZ MHC) Kota Dumai dalam meningkatkan kualitas pendidikan di Kota Dumai. Metode analisis yang digunakan dalam penelitian ini adalah metode analisis deskriptif kualitatif dan metode triangulasi. Pada hasil penelitian ini menunjukkan bahwa Lembaga Amil Zakat Madhani Human Care (LAZ MHC) berupaya meningkatkan kualitas pendidikan di Kota Dumai dengan mengunakan peranan praktik agen dan struktur. Terdapat tiga agen dalam mealukan pemberdayaan dana zakat dibidang pendidikan yang mengawali perubahan dengan kesadaran diskursifnya. Peran yang dilakukan dalam perubahan sosial dalam bidang pendidikan adalah dengan cara sosialisasi, kepercayaan, komunikasi, interprestasi dan nilai moral. Peranan struktur berawal dari kondisi pendidikan Kota Dumai yang kurang baik sehingga adanya peranan Lembaga Amil Zakat Madhani Human Care (LAZ MHC), Dinas Pendidikan dan kebudayaan beserta Dinas Sosial dalam mewujudkan pendidikan berkualitas lebih baik di Kota Dumai. Adapun hubungan antara agen dengan struktur dalam penelitian ini terjadi melalui skema struktur dominasi (penguasaan agen terhadap struktur), signifikansi (ajakan agen pada struktur), dan mencapai skema legitimasi (pembenaran atas upaya agen oleh struktur).
Implementasi Design Thinking pada Proses Desain Tas Tranportasi Barang Untuk Pengendara Roda Dua
Authors: Peranginangin Ezra , Vincent Vincent 
Published: April 2022

Penelitian ini bertujuan untuk mengeksplorasi implementasi desain thinking khususnya dalam Model bisnis digital membutuhkan realisasi layanan transportasi yang praktis dan cepat dengan menggunakan kendaraan roda dua. Disamping kepraktisan sepeda motor roda dua, terdapat beberapa kelemahan yang esensial ketika alat transportasi diaplikasikan sebagai media pengantar barang, yaitu: jaminan kualitas barang yang diantarkan, kapasitas penyimpanan, dan kebutuhan akan tempat penyimpanan yang mampu mengurangi penggunaan pengemas barang tambahan. Pendekatan pemikiran desain (design thinking) merupakan metode non linear dengan proses yang iterative dalam mengidentifikasi ill-design problem untuk memberikan solusi yang inovatif. Ojek online merupakan sebuah layanan pesan antar bagi pengguna yang ingin pergi, mengantarkan barang, memesan makanan, dan sebagainya melalui aplikasi telepon genggam dan diakses dengan menggunakan internet. Ojek online terutama yang menggunakan sepeda motor memiliki banyak keterbatasan. Keterbatasan ini didasari oleh tingkat kerentanan yang tinggi terhadap faktor eksternal seperti cuaca, polusi, dan sebagainya. Selain faktor eksternal, kapasitas sepeda motor juga menjadi batasan seseorang dalam membawa barang. Penelitian ini dilakukan dengan menggunakan beberapa metode, antara lain: Studi kepustakaan untuk mendapatkan literatur, observasi terhadap pengemudi Ojek Online, survei terhadap konsumen, dan weighted decision matrix dalam menentukan satu desain terpilih dari beberapa alternatif desain. Selain metode, Peraturan Pemerintah digunakan juga tepatnya Peraturan Pemerintah No.74 tahun 2014. Hasil dari metode-metode tersebut berbanding lurus dengan masalah, banyak yang mengeluhkan proses pengiriman dan kondisi barang yang tidak maksimal. Salah satu bentuk pemecahan masalah adalah dengan merancang produk penunjang, yaitu tas khusus ojek online. Dengan adanya rancangan tas tersebut, diharapkan kinerja para pengemudi ojek online menjadi maksimal dan memberikan kualitas pelayanan yang terjamin.
Analisis Korelasi Tahanan Konus Dengan Nilai Cbr Laboratorium dan Cbr Hasil Uji Dcp Studi Kasus Indragiri Hulu dan Pekanbaru
Authors: Erny Erny 
Published: April 2022

Penyelidikan tanah dibutuhkan untuk data perancangan fondasi bangunan. Penyelidikan tanah ada di lapangan Cone Penetration Test (CPT) dan California Bearing Ratio (CBR) lapangan alat Dynamic Cone Penetrometer (DCP) dan laboratorium (CBR laboratorium), peneliti sebelumnya Rahardjo (1995) memperoleh korelasi CBR dan tahanan konus (qc) pada alat CPT Pada tanah lempung yang dipadatkan CBR= ½ qc dan Schmertmann tanah pasir sebesar CBR = ⅓ qc CBR (In-situ). Berdasarkan data analisis objek penelitian di lokasi pembangunan PKS PT. Inecda (ST.03, ST.04 dan ST.05) di Indragiri Hulu dan pembangunan Jalan Nasional Propinsi Riau (STA 0+600, STA 6+000, dan STA 17+000) di Pekanbaru dengan Pelaksanaan CBR lapangan alat uji DCP sesuai Departemen Pekerjaan Umum tahun 2008 dan CBR laboratorium sesuai SNI-03-1744-1989. Klasifikasi tanah pada CPT berdasarkan cone resistant (qc) dan friction Ratio (fr) di plotkan pada gambar Robertson dan Campanella (1986). Hasil penelitian didapat korelasi CBR laboratorium dengan CBR lapangan alat uji DCP, nilai CBR alat uji yang diperoleh selalu nilai DCP lebih kecil dari CBR laboratorium, Rasio nilai CBR uji DCP berbanding CBR laboratorium berkisar 72% - 90%, dimana pada tanah lempung memiliki nilai lebih tinggi (tanah lempung rasio mendekati CBR laboratorium) dan korelasi nilai tahanan konus dengan CBR laboratorium pada penelitian nilai lebih mendekati teori Schmentmaan pasir CBR= ⅓ qc dan CBR untuk lempung Raharjo (1995) CBR= ½ qc, pada penelitian pasir 0,26 qc dan lempung 0,48 qc sedangkan CBR alat uji DCP pasir 0,21 qc dan lempung 0,42 q dan nilai perbandingan CBR/qc semakin kecil diperoleh jenis tanah baik dan semakin jelek jenis tanah yang di peroleh maka nilai CBR/qc semakin tinggi.
Management Practices and Holistic Development of Dance Troupe in Selected Secondary Schools
Authors: Aquino John Michael D. 
Published: April 2022

Management is a procedure of designing and sustaining an environment where everyone works together to attain the organization's goal. The study is a comparative analysis of the management practices of selected secondary public schools' dance troupe. This study is primarily anchored to the Skills Acquisition Theory (SAT). Specifically, the aims to identify the management practices and holistic development of the dance troupe members. The research study wants to determine the procedures in terms of rehearsals and training, community involvement, qualification of dancers, facilities, financial support, and the level of dancers' attributes in terms of attitude, discipline, and skills. The researcher also wants to determine if there is a significant relationship between the management practices and holistic development on the personal attributes of dance troupe members of the selected secondary public schools. Using a descriptive-quantitative methodology, a self-administered questionnaire was utilized in the survey of 172 dancers. The results revealed that dancers are well-disciplined and highly skilled. The management of the dance troupe struggles in terms of qualifications of the members, facilities, and financial support, which ultimately affect their preparation and training programs. Hence, there is a significant relationship between the management practices and holistic development of dance troupe members. The dance troupe's practices, skills, attitudes, and discipline have to maintain.
representação de gêneros nos tempos de Cervantes: La Española Inglesa
Authors: Ribeiro Lopes de Almeida Edwirgens Aparecida 
Published: April 2022

Resumo: A narrativa curta La española inglesa, publicada por Miguel de Cervantes em 1613, faz parte da coleção de doze contos chamada Novelas Ejemplares. Nas temáticas encontradas nessas narrativas, temos o casamento, o ciúme, a religião, os negocios navais, a situação social da Espanha no Século de Ouro. Desse modo, La española Inglesa oferece ao leitor deleite e reflexão sobre a ocupação social da mulher nas relações de gênero. Por meio de um olhar verossímil sobre as ideias e as práticas predominantes naquele contexto, a ficção vai além da representação e encena um teor crítico e irônico das circunstâncias a que eram submetidas as mulheres nos tempos de Cervantes.

Palavras chave: século de ouro, mulher, tradição, crítica.