bluuebunny/crossref_metadata_2025_split huggingface dataset:
КЛІНІЧНЕ ЗНАЧЕННЯ ДОСЛІДЖЕННЯ ЛЕПТИНУ СИРОВАТКИ КРОВІ ПРИ ЕНДОМЕТРІОЗІ
Authors: Остафійчук Світлана , Дзьомбак Володимир , Левицький Ігор , Кравчук Інна , Кінаш Наталія , Моцюк Юлія 
Published: June 2022

Актуальність. Вивчення ендометріозу визначаються значним поширенням даної патології, прогресуючим перебігом, розвитком хронічного тазового болю, диспареунії, непліддя, що порушує якість життя жінки.
Мета дослідження. Дослідили асоціацію рівня лептину в сироватці крові жінок з ендометріозом зі стадією тяжкості патологічного процесу.
Матеріали та методи. У дослідження залучено 69 пацієнток з діагнозом ендометріозу (основна група) і 47 жінок без гінекологічної патології (контрольна група), які проходили обстеження і оперативне лікування у міському клінічному перинатальному центрі, м. Івано-Франківськ, Україна. Ступінь тяжкості ендометріозу встановлювали згідно наказу МОЗ України № 319 від 6.04.2016 року. Кількісне визначення лептину в сироватці крові проводили методом імуноферментного аналізу (ELISA Kit № CAN-L-4260, Canada). Результати статистично аналізували за допомогою Statistica 12.0 (StatSoft Inc., США) та пакету статистичного аналізу Microsoft Excel.
Результати. Пацієнтки обох груп вірогідно не різнилися за індексом маси тіла (р˃0,05). Середній показник лептину у жінок основної групи у 3,2 рази перевищував рівень гормону у контрольній групі (28,94±7,20 нг/мл проти 12,11±4,16 нг/мл) (р<0,05). 55,1 % жінок з ендометріозом мали показник лептину від 20,00 до 29,99 нг/мл, що у 6,5 разів перевищувало частоту жінок контролю (р<0,05). Встановлено збільшення показника лептину при прогресуванні стадії тяжкості ендометріозу: при І стадіїї середня різниця становила 8,82±2,71 нг/мл (р<0,05), при ІІ – 14,86±2,63 нг/мл (р<0,001), при ІІІ – 18,12±3,69 нг/мл (р<0,001), при ІV – 26,99±3,52 нг/мл (р<0,001) порівняно з показником лептину групи контролю (12,11±4,16 нг/мл). Отже, зростання рівня лептину у 1,7 разів збільшує шанси ендометріозу І стадії тяжкості (OR=4,43; 95% CІ: 2,01-9,78; р<0,001), у 2,2 рази – ІІ стадії (OR=4,09; 95% CІ: 1,29-12,94; р<0,05), збільшення гормону у 2,4 рази підвищує шанси ІІІ стадії (OR=3,51; 95% CІ: 1,10-11,23; р<0,05), а у 3,2 рази – ІV стадії тяжкості (OR=3,79; 95% CІ: 1,19-12,07; р<0,05).
Висновки. Лептин можна вважати прогностичним маркером встановлення ендометріозу та діагностики ступеня тяжкості.
Pharmacological Maneuver of Mangrove Endophytic Fungi in the South China Sea – A review
Authors: Narayanan Manjula Muthu , Shivanand Pooja , Ahmad Norhayati 
Published: June 2022

Conventional products have a role in addressing the thriving universal demands for biologically active substances. Since the South China Sea is a prodigious province of geostrategic and mercantile importance, it meets the basic needs of people who dwell there. The South China Sea is dominant in mangrove biodiversity which, represents 11.4% of the world’s 15.5 million hectares of mangrove forest. Mangroves are harbored by multifaceted fungal communities that represent the second colossal ecological breed of marine fungi. The symbiotic association between the plants and fungi stimulates the bioactive components such as alkaloid, depsipeptides, cyclic peptides, quinone, terpenes, lactones, terpenoid, flavonoid, phenolic acid, steroids. These components have multifaceted pharmacological activities likely, anti-inflammatory, antidiabetic, anticancer, antioxidant, and antimicrobial. This review article attempts to present a piece of insightful information currently being explored on the biologically active components generated by mangrove endophytic fungi of the South China Sea.
Peran Perempuan dalam Peternakan Sapi Perah pada Kelompok Tani ternak Desa Samiran, Boyolali, Jawa Tengah
Authors: Satiti Endah , Andarwati Siti , Kusumastuti Tri Anggraeni 
Published: June 2022

Perempuan memiliki kontribusi penting dalam usaha peternakan sapi perah khususnya daerah pedesaan di negara berkembang. Namun, peran perempuan dalam usaha budi daya sapi perah di Indonesia masih belum banyak dikaji. Tujuan penelitian ini adalah mengidentifikasi karakteristik peternak sapi perah dan mengkaji peran perempuan dalam tata laksana usaha ternak sapi perah. Secara khusus penelitian ini akan meninjau peran perempuan dalam aktivitas dan kontrol, akses modal, akses bahan baku dan peralatan, serta manfaat bagi dua Kelompok Tani Ternak, kelompok tani ternak Berdaya dan Kelompok Tani Ternak Aura. Lokasi penelitian ini terletak di Desa Samiran Kecamatan Selo Kabupaten Boyolali Jawa Tengah, penelitian ini memilih dua kelompok tani ternak yang ditentukan berdasarkan pertimbangan menjadi salah satu sentra produksi susu sapi. Responden yang dilibatkan dalam penelitian ini melibatkan 49 responden peternak dari kedua Kelompok Tani Ternak yang ditentukan menggunakan metode sensus. Penelitian dilaksanakan melalui survei menggunakan kuesioner terstruktur yang telah dipersiapkan sebelumnya dengan pendekatan Level of Effort (LoE) dan Level of Control (LoC) yang didasarkan pada karakteristik demografi dan peran perempuan di dalamnya. Hasil penelitian menunjukkan bahwa peternak dari kedua Kelompok Tani Ternak masih dalam usia produktif (>92%), telah mengenyam pendidikan formal (100%), dan mayoritas telah memiliki pengalaman beternak lebih dari 15 tahun (>36%). Berkaitan dengan peran perempuan hasil penelitian ini menunjukkan bahwa perempuan kurang dalam mengakses informasi dari luar kelompok dibandingkan laki-laki. Perempuan dan laki-laki dari kedua kelompok memberikan kepercayaan penuh (100%) kepada kelompok untuk mengelola modal yang bersumber dari biaya pribadi dan sama-sama dapat mengakses peralatan budidaya untuk menunjang pelaksanaan pemeliharaan ternak sapi perah, sedangkan pada aktivitas, kontrol, dan kemanfaatan berdasarkan hasil analisis LoE dan LoC menunjukkan perempuan memiliki peranan usaha serta kontrol yang lebih besar dibandingkan laki-laki. Peran mutlak perempuan terutama dari aktivitas manajemen pemerahan dan pengolahan susu, sedangkan peran utama laki-laki pada manajemen perkandangan. Upaya peningkatan peran perempuan dalam usaha budi daya perlu dilakukan oleh pemangku kepentingan melalui penetapan kebijakan untuk meningkatkan pemberdayaan perempuan melalui program dan bantuan modal.
Characteristics of Pulmonary Tuberculosis Patients in RSUD Prof. DR. W. Z. Johannes Kupang
Authors: Wijaya Evelyn Danielle , Wartiningsih Minarni 
Published: June 2022

Tuberculosis is an infectious disease caused by the bacteria Mycobacterium tuberculosis and contributes to one of the top 10 causes of death in the world. Tuberculosis sufferers in Indonesia are ranked as the 2nd most in the world. Tuberculosis cases in the province of East Nusa Tenggara continue to increase from year to year, especially in the Kupang city. Data of inpatient pulmonary tuberculosis patients in RSUD Prof. Hospital DR. W.Z. Johannes Kupang from 2017 to 2018 increased with 238 cases to 275 cases. This study aims to determine the characteristics of pulmonary tuberculosis patients hospitalized in RSUD Prof. DR. W.Z. Johannes Kupang. This research was conducted using the descriptive observational methods. Data collected using medical records with purposive sampling obtained a sample size of 51. The results of the study and conclusions showed that the majority of pulmonary tuberculosis patients hospitalized in RSUD Prof. DR. W.Z. Johannes Kupang consist of 60.8% of the male sex, 35.3% of the 45-55 year age group, 35.3% of primary school education status, and 54.9% of AFB smear-positive sputum.
The Association Between Knowledge About Gout Arthritis with NSAID and Allopurinol Consumption in Rumah Susun Penjaringan
Authors: Santoso Brigita Naomi , Suwangto Erfen Gustiawan , Iryaningrum Maria Riastuti 
Published: June 2022

Background: Health ministry is one of ministries in Indonesia who needs high fund every year. It is used for national health, starting from the availability of health infrastructure to the availability of medicine in health primary care and hospital. In Indonesia, there is a myth that joint pain is gout arthritis. In Indonesia, 71% people who have joint pain buy pain killer without going to get an examination by doctor first. Therefore, a research about the relationship between knowledge about gout arthritis and NSAID and Allopurinol consumption in Rumah Susun Penjaringan. Objective : Knowing if there is association between knowledge about gout arthritis and NSAID and Allopurinol consumption. Methods : This research used cross sectional study and involved 68 people in Rumah Susun Penjaringan. Result : There is no significant relationship between knowledge about gour arthritis with NSAID (p = 0.234) and Allopurinol (0.666) consumption in Rumah Susun Penjaringan. Conclusion : There is no relationship between knowledge about gout arthritis with NSAID and Allopurinol consumption in Rumah Susun Penjaringan.
Effects of Family Function on Blood Sugar Control in Patients with Type 2 Diabetes Mellitus
Authors: Fathonah Yayuk , Fauziyati Ana , Malik Muhammad , Hanif Muhammad 
Published: June 2022

Background: A long term treatment can happen for patients with diabetes mellitus (DM), which can negatively affect their lives and their families. Family support is an important factor to help them adapt to their DM and maintain their self-management. Doctors must assess family function of the patients with DM during their treatment.Objective: This study aimed to observe the effects of family function on blood sugar control in type 2 DM patients who were included in PROLANIS (chronic disease management program) at Puskesmas Banguntapan 2 Bantul, D.I. Yogyakarta, Indonesia.Methods: This quantitative analytical study was conducted with a cross-sectional design in November-December 2019 by using the Family APGAR instrument and fasting blood sugar tests from the DM patients’ venous blood. Its sampling technique was the total sampling of the PROLANIS participants who suffered from DM and met inclusion criteria of this study. All obtained data of this study were analyzed by Spearman Product Moment analysis to determine the effects of family function on their fasting blood sugar levels.Results: This study found that there was a significant effect of family function on blood sugar control in the patients with type 2 DM (p=0.008). This finding indicated that the family function was an important aspect in controlling their blood sugar.Conclusion: The family function was an influential factor to optimize the treatment of patients with type 2 DM. The assessment on the family function should be a part of their routine examination in primary healthcare units.
Analisis kebutuhan E-book Mikrobiologi Terapan berbasis Kekayaan Lokal Jambi untuk Menumbuhkan Jiwa Berwirausaha
Authors: Budiarti Retni S , Harlis Harlis 
Published: June 2022

The purpose of this study was to determine the need for an e-book of applied microbiology based on Jambi's local wealth to foster an entrepreneurial spirit in the Biology Education Study Program, Jambi University. This research is a qualitative descriptive study. The method used in the form of interviews and questionnaires to students. The data were analyzed using descriptive analysis and the percentage of the answers given was divided by the total number of respondents multiplied by 100%. The results of this study indicate that: (1) microbiology learning has not used project-based learning in accordance with Jambi's local wealth based to foster an entrepreneurial spirit; (2) 97.1% of students are interested in applied microbiology materials applied to foster an entrepreneurial spirit by utilizing local Jambi wealth (3) 88.2% of students have never had applied microbiology teaching materials in the form of e-books based on Jambi's local wealth to foster an entrepreneurial spirit as material teach the learning process. The conclusion of this study is that it is necessary to develop teaching materials in the form of an e-book of applied microbiology based on Jambi's local wealth to foster an entrepreneurial spirit.

Key words: E-Book, Microbiology, Entrepreneurship

Abstrak

Tujuan penelitian adalah untuk mengetahui kebutuhan terhadap e-book mikrobiologi terapan berbasis kekayaan lokal Jambi untuk menumbuhkan jiwa berwirausaha di Prodi Pendidkan Biologi Universitas Jambi. Penelitian ini merupakan penelitian deskriptif kualitatif. Metode yang digunakan berupa wawancara dan kuesioner pada mahasiswa. Data dianalisis menggunakan analisis deskriptif dan prosentase dari hasil jumlah jawaban yang diberikan dibagi jumlah seluruh responden dikali 100%. Hasil penelitian ini menunjukkan bahwa: (1) pembelajaran mikrobiologi belum menggunakan pembelajaran berbasis proyek sesuai dengan berbasis kekayaan lokal Jambi untuk menumbuhkan jiwa berwirausaha; (2) 97,1% mahasiswa tertarik materi mikrobiologi terapan diterapkan untuk menumbuhkan jiwa kewirausahaan dengan memanfaatkan kekayaan lokal jambi (3) 88,2% mahasiswa belum pernah bahan ajar mikrobiologi terapan berbentuk e-book berbasis kekayaan lokal Jambi untuk menumbuhkan jiwa berwirausaha sebagai bahan ajar proses pembelajaran. Kesimpulan dari penelitian ini adalah perlu dikembangkan bahan ajar berupa e-book mikrobiologi terapan berbasis kekayaan lokal Jambi untuk menumbuhkan jiwa berwirausaha.

Kata kunci: E-Book, Mikrobiologi, Berwirausaha
Unexpected partial RNA deletion by two different novel COL6A2 mutations leads to Ullrich congenital muscular dystrophy
Authors: Xu Songchao , Li Liangshan , Shen Lu , Wang Xiaoyu , Feng Wei , Liu Shi 
Published: June 2022

Limb weakness is an uncommon symptom in children, with multiple
factors contributing to related diseases, particularly genetic
disorders. A nine-year-old boy presented with slowly progressive muscle
weakness of the limb-girdle muscles. We evaluated the clinical symptoms,
laboratory tests, imaging examinations, and pathological examinations of
this proband. We combined whole-exome and Sanger sequencing to identify
the novel compound heterozygous pathogenic mutations NM 001849.3:
c.1970-10_1978 del CGGCTTGCAGGGACGCGTG and c.2462-3C>A in
COL6A2 in this proband inherited from the mother and father,
respectively. Mutational confirmation at the mRNA level demonstrated
that the proband carried a homozygous abnormal sequence with 23bp
deletions (c.2462-2484 del GGACGCGTGTGGGCGTGGTGCAG) at the beginning of
exon 26. In contrast, both parents and sibling have normal sequences
with no clinical symptoms. The results of this study further expand the
mutational spectrum and will be helpful for further molecular diagnosis.
Effects of broiler chicken age and dietary protease on the standardised ileal digestibility of amino acids in seeds from two lupin species
Authors: Szczurek Witold , Świątkiewicz Sylwester 
Published: June 2022

Abstract
The extent to which lupin seeds can replace soybean meal in diets for broiler chickens is limited, and one of the reasons for this may be a lack of careful consideration given to the age-related amino acid availability differences in the feed formulation process. This study aimed to determine and compare standardised ileal digestibility (SID) coefficients of amino acids (AA) in raw seeds of the Lupinus luteus (YL) and the Lupinus angustifolius (NLL) cultivars as sole sources of AA in the diet of broiler chickens aged 14 or 28 days. An additional purpose was to check the influence of exogenous mono-component protease added to lupin-based assay diets on AA SID in birds at both ages. Each assay diet was offered to six replicatecages. On both sampling days, the contents from the lower half of the ileum were collected for determination of the apparent digestibility values. The SID coefficients were calculated using the age-appropriate basal ileal endogenous AA losses determined from birds fed a N-free diet. Results indicated a substantial advantage of YL over the NLL in SID of Met, Cys, His, Leu, Gly, Asp, Glu, Pro, Tyr and the average of total AA for 14-d-old chickens. With the exception of Cys and Tyr, there was no significant difference between these Lupinus species in the SID of AA in 28-d-old birds. The significant age-related differences within species were found only for the seeds of NLL, where the higher SID for Met, His, Ala, Pro, and the averages of total and indispensable AA were noted in birds aged 28 d. The protease increased SID of most AA from L. luteus in older broilers, whereas for L. angustifolius its efficacy was more pronounced in younger birds, giving the SID values similar to those determined at 28 d on an enzyme-unsupplemented diet. In conclusion, the SID coefficients of indispensable AA determined at 14 or 28 days of age for yellow lupin should not be applied to the precise formulation of starter-type feeds containing seeds of NLL.
When Brazil Got the Blues: The Diffusion of Blues in Brazil
Authors: Marcus Alan P. 
Published: June 2022

The focus of this article is to understand and examine the phenomenon of the introduction of blues as a musical genre in Brazil (1985-1992), which has never been studied. By highlighting the processes of globalization and the Brazilian blues band from Rio de Janeiro, Blues Etílicos, I ask what were the spaces, places, and venues that helped to disseminate blues throughout Brazil? How does an African-American-based genre adopted and popularized by upper-and-middle-class white urbanites in Brazil? To answer these questions, I examine political, musical, and cultural backdrops, and the end of Brazil’s military dictatorship in 1985, which overlapped with a major Brazilian rock festival, “Rock in Rio,” and Brazil’s first blues festival in Ribeirão Preto in 1989. This article adds to the scholarly literature of blues and music geography by looking at ongoing discussions of Brazil’s changing political, cultural, and musical landscapes.
Música Popular Black and anti-racist struggles: musical cosmopolitanism and the soul aesthetic in Brazil (1963-1978)
Authors: Treece David 
Published: June 2022

This essay reassesses the political significance of the creative impulses, performance aesthetics and artistic work that became identified collectively as música popular black, and their contribution to the anti-racist cause in Brazil during the 1964-85 dictatorship. It reevaluates how the state orthodoxy of racial nationalism and denialism was challenged, not merely in the adoption of the soul aesthetic as a marker of diasporic identification with US blackness, but in the cumulative emergence of an autonomous anti-racist consciousness and voice for Afro-Brazilians within their own musical and social world. This was expressed, not only in a body of powerfully explicit anti-racist statements but also in a creolized, cosmopolitan idiom of vocal and performative style that connected local artists and the Black Rio dance scene, and that contributed to the building of a Black public sphere, leaving a potent legacy for the musical and political movements of the 1980s, 1990s and beyond.
Politização indígena e crise da política indigenista no Brasil.
Authors: Faulhaber-Barbosa Priscila 
Published: June 2022

Inspirada na hermenêutica dos paradigmas da antropologia, no exame crítico dos discursos oficiais sobre os índios indicarei, em traços gerais, as críticas das teorias da mudança cultural a partir das definições de contato, fronteiras étnicas e situação histórica, na leitura de autores que formularam suas contribuições a partir de etnografias de etnias da bacia amazônica. Tal abordagem relacional é eticamente fundamentada, ainda que provisória, em constante reformulação. A seguir, elucidarei o meu ponto de vista do conflito entre legislações, característico da atual política indigenista brasileira tocando permanência de práticas tutelares e que inclui os problemas relacionados a movimentos indígenas, organizações e participação institucional.
STUDI KARAKTERISTIK MORFOMETRIK DAN MERISTIK SEMBILANG (Plotosus canius) DI PERAIRAN LANGSA
Authors: Suransyah Aldi , AS Agus Putra , Rozalina Rozalina , Junita Afrah 
Published: June 2022

Sembilang (Plotosus canius) adalah ikan yang termasuk dalam famili Plotosidae. Ikan ini sangat digemari oleh masyarakat karena memiliki rasa yang enak dan bergizi. Penelitian ini dilakukan untuk mendapatkan data morfometrik dan meristik ikan sembilang di perairan Langsa. Pengetahuan tentang aspek morfometrik dan meristik sembilang sangat diperlukan untuk mencegah menurunnya populasi ikan di suatu perairan. Morfometrik adalah ciri yang berkaitan dengan ukuran tubuh atau bagian tubuh ikan seperti panjang total, sedangkan meristik merupakan ciri-ciri dalam taksonomi. Pengambilan data dilaksanakan selama Januari - April 2021. Dari 100 ekor sampel, panjang ikan adalah 21-39 cm dengan berat 85-280 gr. Hubungan panjang berat ikan bersifat allometrik negatif dengan nilai rata-rata r = 0.996698. Pada faktor kondisi ikan bernilai 1.003 yang berarti dalam hal ini nilai rata-rata faktor kondisi <3 yang bersifat allometrik negatif
Pengembangan PENGEMBANGAN GAME EDUKASI MEMBACA DAN MENULIS UNTUK MENINGKATKAN KEMAMPUAN BAHASA ANAK USIA 5-6 TAHUN DALAM HAL KEAKSARAAN DI TK ISLAM BHAKTI 5 YPBWI
Authors: Arya Adisa Jasmine 
Published: June 2022

ABSTRACT
This study aims to determine the results of the development of educational gamesto improve language skills in terms of literacy using Power Point, determine the feasibility of educational games (Guess the Picture) Vocabulary Reading and Writing in Indonesian as a learning medium to improve student learning outcomes at Islamic Kindergarten Bhaki 5 YPBWI Gresik based on Power Point, and find out student responses to the use of Power Point-based reading and writing educational games as learning media with basic material of recognizing animal names through a series of vocabulary and then answering the questions listed in the reading and writing educational game, and aims to determine the feasibility of the media as a learning medium.
The research method used is development or known as the Research and Development method. The stages in the research process are the analysis, design, development, implementation, and testing stages. The tests carried out are in the form of validation by media and material experts. Then the media was tested by students. After validation has been carried out and the media meets the appropriate interactive criteria, then testing or research is carried out to determine the feasibility in the field. This research was conducted at TK Islam Bhakti 5 YPBWI Gresik involving 17 students. The method used in data collection is a questionnaire, the data obtained is then analyzed by descriptive analysis technique. In this study, the results of the feasibility of media experts on an average of 81% were included in the appropriate category. Material experts on an average of 100% are included in the very feasible category, and the results of student trials are on average 70% and field test results of 79% are very feasible included in the good category. Based on the results of the study, it can be concluded that overall the learning media for developing reading and writing educational games to improve children's language skills in terms of literacy is appropriate to be used as a medium in the learning process in kindergarten group B children.

Keywords
Development, Eligibility, Learning Media