bluuebunny/crossref_metadata_2025_split huggingface dataset:
Variation in the reproductive quality of honey bee males affects their age of flight attempt
Authors: Metz Bradley N. , Tarpy David R. 
Published: August 2022

Background
Honey bee males (drones) exhibit life histories that enable a high potential for pre- or post-copulatory sperm competition. With a numerical sex ratio of ∼11,000 drones for every queen, they patrol flyways and congregate aerially to mate on the wing. However, colonies and in fact drones themselves may benefit from a relative lack of competition, as queens are highly polyandrous, and colonies have an adaptive advantage when headed by queens that are multiply mated. Previous research has shown that larger drones are more likely to be found at drone congregation areas, more likely to mate successfully, and obtain a higher paternity share. However, the reproductive quality and size of drones varies widely within and among colonies, suggesting adaptive maintenance of drone quality variation at different levels of selection.

Methods
We collected drones from six colony sources over the course of five days. We paint marked and individually tagged drones after taking body measurements at emergence and then placed the drones in one of two foster colonies. Using an entrance cage, we collected drones daily as they attempted flight. We collected 2,420 drones live or dead, analyzed 1,891 for attempted flight, collected emergence data on 207 drones, and dissected 565 upon capture to assess reproductive maturity. We measured drone body mass, head width, and thorax width at emergence, and upon dissection we further measured thorax mass, seminal vesicle length, mucus gland length, sperm count, and sperm viability from the seminal vesicles.

Results
We found that drones that were more massive at emergence were larger and more fecund upon capture, suggesting that they are of higher reproductive quality and therefore do not exhibit a trade-off between size and fecundity. However, smaller drones tended to attempt initial flight at a younger age, which suggests a size trade-off not with fecundity but rather developmental maturation. We conclude that smaller drones may take more mating flights, each individually with a lower chance of success but thereby increasing their overall fitness. In doing so, the temporal spread of mating attempts of a single generation of drones within a given colony increases colony-level chances of mating with nearby queens, suggesting an adaptive rationale for high variation among drone reproductive quality within colonies.
Neurological and Molecular Interactions of Phytoconstituents from Ricinus communis Root Extract- A Pharmacological and Computational Approach
Authors: Raju M. Ganga , Prasanna V. Laxmi , Reddy V N. V. L. Suvarchala , Sneha Ch. 
Published: August 2022

The majority of epileptic patients takes numerous anticonvulsant medications and is still not treated successfully. These medications' produce chronic side effects and drug interactions, which restrict their use, constitute their major drawback. On the other hand, the fact that nature has given us plants that can be used as safe, all-natural treatments for illnesses with little side effects and minimal drug interactions has prompted researchers to focus on herbal remedies with anticonvulsant potential. The antiepileptic potential of the methanolic root extract of Ricinus communis was investigated in rodent models. Molecular docking studies using Schrodinger software was employed to study interactions with active site using PDB ID: 4MS4 (GABA agonist’s), 3WFG (glutamate antagonist), 5HCV (aspartate antagonist), 6J8G (sodium channel antagonist). At 30 and 60 minutes, MERC effectively diminished various convulsive phases and provided strong defence against the MES model. In PTZ, MERC extract treated groups at a dose (200 mg/kg and 400 mg/kg) showed significant antiepileptic activity with percentage protection of 24% and 33% respectively against seizures and significantly (* = p<0.0001) increased the latency of the seizures. Molecular docking studies confirmed the GABA agonist’s effects, and the results revealed that quercetin. gallic acid, luteolic acid, gentixic acid, catechin, vanillic acid, ricinoilc acid and standard phenytoin, clonazepam has highest Glide scores against all the selected proteins which indicates a stronger receptor -ligand binding affinity. From in vivo and molecular docking results it is clear that methanolic root extract of Ricinus communis possessed significant antiepileptic activity.
Tailoring the Thickness‐Dependent Optical Properties of Conducting Nitrides and Oxides for Epsilon‐Near‐Zero‐Enhanced Photonic Applications
Authors: Saha Soham , Ozlu Mustafa Goksu , Chowdhury Sarah N. , Diroll Benjamin T. , Schaller Richard D. , Kildishev Alexander , Boltasseva Alexandra , Shalaev Vladimir M. 
Published: August 2022

AbstractThe unique properties of the emerging photonic materials, conducting nitrides and oxides, especially their tailorability, large damage thresholds, and, importantly, the so‐called epsilon‐near‐zero (ENZ) behavior, have enabled novel photonic phenomena spanning optical circuitry, tunable metasurfaces, and nonlinear optical devices. This work explores direct control of the optical properties of polycrystalline titanium nitride (TiN) and aluminum‐doped zinc oxide (AZO) by tailoring the film thickness, and their potential for ENZ‐enhanced photonic applications. This study demonstrates that TiN–AZO bilayers support Ferrell–Berreman modes using the thickness‐dependent ENZ resonances in the AZO films operating in the telecom wavelengths spanning from 1470 to 1750 nm. The bilayer stacks also act as strong light absorbers in the ultraviolet regime using the radiative ENZ modes and the Fabry–Perot modes in the constituent TiN films. The studied Berreman resonators exhibit optically induced reflectance modulation of 15% with picosecond response time. Together with the optical response tailorability of conducting oxides and nitrides, using the field enhancement near the tunable ENZ regime can enable a wide range of nonlinear optical phenomena, including all‐optical switching, time refraction, and high‐harmonic generation.
Effect of particles on hydrodynamics and mass transfer in a slurry bubble column: Correlation of experimental data
Authors: Zhang Huahai , Guo Zhongshan , Wang Yuelin , Shen Xiankun , Wang Tiefeng 
Published: August 2022

AbstractThe effects of particle concentration and size on hydrodynamics and mass transport in an air–water slurry bubble column were experimentally studied. When the particle concentration αs increased from 0% to 20%, the averaged gas holdup decreased by ~30%, gas holdup of small bubbles and gas–liquid volumetric mass transfer coefficient decreased by up to 50%, while the gas holdup of large bubbles increased slightly. The overall effect of particle size was insignificant. A liquid turbulence attenuation model which could quantitatively describe the effects of particle concentration and size was first proposed. Semi‐empirical correlations were obtained based on extensive experimental data in a wide range of operating conditions and corrected liquid properties. The gas holdup and mass transfer coefficient calculated by the correlations agreed with the experimental data from both two‐phase and three‐phase bubble columns, with a maximum error <25%.
Brain Connectivity Predicts Chronic Pain in Acute Mild Traumatic Brain Injury
Authors: Bosak Noam , Branco Paulo , Kuperman Pora , Buxbaum Chen , Cohen Ruth Manor , Fadel Shiri , Zubeidat Rabab , Hadad Rafi , Lawen Amir , Saadon‐Grosman Noam , Sterling Michele , Granovsky Yelena , Apkarian Apkar Vania , Yarnitsky David , Kahn Itamar 
Published: August 2022

ObjectivesPrevious studies have established the role of the cortico‐mesolimbic and descending pain modulation systems in chronic pain prediction. Mild traumatic brain injury (mTBI) is an acute pain model where chronic pain is prevalent and complicated for prediction. In this study, we set out to study whether functional connectivity (FC) of the nucleus accumbens (NAc) and the periaqueductal gray matter (PAG) is predictive of pain chronification in early‐acute mTBI.MethodsTo estimate FC, resting‐state functional magnetic resonance imaging (fMRI) of 105 participants with mTBI following a motor vehicle collision was acquired within 72 hours post‐accident. Participants were classified according to pain ratings provided at 12‐months post‐collision into chronic pain (head/neck pain ≥30/100, n = 44) and recovery (n = 61) groups, and their FC maps were compared.ResultsThe chronic pain group exhibited reduced negative FC between NAc and a region within the primary motor cortex corresponding with the expected representation of the area of injury. A complementary pattern was also demonstrated between PAG and the primary somatosensory cortex. PAG and NAc also shared increased FC to the rostral anterior cingulate cortex (rACC) within the recovery group. Brain connectivity further shows high classification accuracy (area under the curve [AUC] = .86) for future chronic pain, when combined with an acute pain intensity report.InterpretationFC features obtained shortly after mTBI predict its transition to long‐term chronic pain, and may reflect an underlying interaction of injury‐related primary sensorimotor cortical areas with the mesolimbic and pain modulation systems. Our findings indicate a potential predictive biomarker and highlight targets for future early preventive interventions. ANN NEUROL 2022;92:819–833
Optically stimulated luminescence properties of commercially available KCL dietary supplements as retrospective dosimeters
Authors: Szufa Katarzyna M. , Majgier Renata 
Published: August 2022

AbstractIn the case of an unexpected exposure to radiation in places where there is no access to standard dosimeters, materials that can act as detectors in methods of retrospective dosimetry are looked for. Such materials include, but are not limited to, medicines and dietary supplements that are found in households or in personal bags. This article presents the optically stimulated luminescence (OSL) dosimetric properties of dietary supplements, the main ingredient of which is a sensitive phosphor – potassium chloride (KCl). Three types of KCl dietary supplements were tested and compared to a selection of four common drugs in terms of their sensitivity. Basic dosimetric properties of dietary supplements such as signal repeatability, dose response and fading were determined. The dose recovery test was performed 2 and 7 days after exposure to radiation. The obtained dose values for the two supplements showed good compliance with the nominal dose values and the possibility of correctly assigning the doses to the levels of triage (low dose 0–1 Gy, medium dose 1–2 Gy and high dose > 2 Gy). The presented results show that dietary supplements with KCl have the potential to be used as emergency detectors in the dose recovery process.
Effect of static and dynamic jaw positions on postural stability among people with blindness
Authors: Alghadir Ahmad H. , Zafar Hamayun , Ahmed Iqbal Zaheen , Anwer Shahnawaz , Iqbal Amir 
Published: August 2022

AbstractBackgroundIn comparison with the people with normal sight, the mean center of gravity (COG) velocity is significantly higher among blind people. A strong relationship has been shown between jaw and neck sensorimotor and postural control. The purpose of this study was to determine the effect of different static and dynamic jaw positions on postural stability among subjects with blindness.MethodsPostural stability was measured as COG velocity in 39 blind subjects under the following five conditions: resting jaw (natural jaw position with no instructions, control), open jaw (teeth of both jaws slightly apart), clenched jaw (teeth tightly closed across each other), chewing (a standard bolus of gum at the natural palace), and tongue position (positioned behind the upper incisors) while standing on firm and foam surfaces.ResultsThe mean COG velocity while standing on the firm surface during resting, open jaw position, clenched jaw position, chewing, and tongue positions were 0.54, 0.50, 0.44, 0.59, and 0.46 deg/s, respectively. The mean COG velocity while standing on the foam surface during resting, open jaw position, clenched jaw position, chewing, and tongue positions were 1.42, 1.23, 1.10, 1.14, and 1.06 deg/s, respectively. Compared to the firm surface, the COG velocity was significantly higher on the foam surface in all five conditions (p < .001). In the comparison between the conditions, there were no significant differences in either the firm or foam surface in all five conditions (p > .05).ConclusionPeople with blindness behave in the same way as sighted subjects on firm and foam surfaces. However, changes in static and dynamic jaw positions do not affect postural stability among them.
Thermocatalytic Cracking of Frying Oil and Plastic Waste for Production of Organic Liquid Products and Derivatives
Authors: da Silva Mateus Adriano , Serafim Francisco Arleth Prata , Francisco Paulo , Manuel Ngoma , Barros António André Chivanga 
Published: August 2022

AbstractThe use of waste in thermochemical processes, with or without catalysts, to provide environmental solutions, is an effective response to waste generation and offers a solution for providing energy to the transport and industrial sectors. Experiments were carried out using a plug flow reactor (PFR) reactor for the thermal and catalytic cracking of a frying oil and polyethylene terephthalate (PET) mixture, to produce bio‐oil and its derivatives with the same characteristics of crude oil and petroleum derivatives. Mixtures were fed into the PFR reactor for cracking at atmospheric pressure and 450 °C. All the operational conditions were controlled to better evaluate the quality of the products obtained from each reaction. Four experiments were carried out under different conditions. It was observed that increasing the catalyst in the feed flow improved the organic liquid product (OLP) yield. The experiments carried out showed the distribution of boiling points for the products and their derivatives in the distillation as well as the carbon number in the respective chains.
Trigonal Planar Au@Ag3Clusters Showing Exceptionally Fast and Efficient Phosphorescence in Violet to Deep‐Blue Region
Authors: Artem'ev Alexander V. , Baranov Andrey Yu. , Berezin Alexey S. , Lapteva Ulyana A. , Samsonenko Denis G. , Bagryanskaya Irina Yu. 
Published: August 2022

AbstractWe report here a series of original ligand‐supported trigonal planar Au@Ag3clusters exhibiting bright solid‐state phosphorescence in violet to deep‐blue range (λmax=410–442 nm) with remarkably short decay times (0.36–1.36 μs) and up to 96 % emission quantum yield at 298 K.
Benefits of tolvaptan on early dyspnea relief in patients with acute heart failure: A meta‐analysis
Authors: Shang Wenli , Zhang Yingying , Han Dong 
Published: August 2022

AbstractConsidering the prevalence of dyspnea in acute heart failure (AHF), its reduction is important to both patients and caregivers. This meta‐analysis was performed to determine the efficacy and safety of tolvaptan on early dyspnea relief in patients with AHF. A systematic search was made of PubMed, Embase, Web of Science, Cochrane Library, and clinicaltrials.gov, without language restrictions. Randomized controlled trials (RCTs) on treatment of AHF with tolvaptan, compared with placebo or blank, were reviewed. Studies were pooled to relative risk (RR), with 95% confidence interval (CI). Five RCTs (enrolling 4857 participants) met the inclusion criteria. Tolvaptan presented significant effects on 12 h dyspnea relief (RR: 1.98; 95% CI: 1.24−3.15; p = .004), 24 h/day 1 dyspnea relief (RR: 1.15; 95% CI: 1.07−1.24; p = .0003), 48 h dyspnea relief (RR: 1.20; 95% CI: 1.06−1.36; p = .004), and 72 h dyspnea relief (RR: 1.18; 95% CI: 1.02−1.37; p = .03). No significant increase was noticed in the incidence of worsening renal function in tolvaptan group (RR: 1.10; 95% CI: 0.87−1.39; p = .43). Tolvaptan treatment significantly improved patient‐assessed dyspnea early and persistently in patients with AHF.
Adaptive multi‐layer clustering strategies based on capacity weight for Internet of Things
Authors: Liu Xingchun , Yu Jingjing , Feng Zhipeng , Wang Hongxv , Tian Hui 
Published: August 2022

SummaryDue to the requirements brought by diversification of IoT applications, differentiation of nodes' capability, dynamic communication environment and demands, the real‐time information of nodes (actual energy consumption, living nodes' density, pairwise nodes' communication radius) should be considered comprehensively for the clustering strategies of wireless sensor networks to achieve efficient, stable, and flexible performance with limited energy and different quality of service (QoS). This article proposes an improved dynamic multi‐layer clustering strategy for various IoT applications with heterogeneous nodes' energy, unpredictable or fast‐changing distribution of alive nodes, and dynamic scenarios. In addition, an adaptive adjustment strategy based on capability weight for multi‐layer clustering network is proposed to reduce the impact of unreasonable head selection cycle of clustering. By analyzing the node energy, the change of node locations and historical data transmission of cluster head, different capability weights are assigned to each node to adaptively re‐cluster the clusters with heavy load and poor performance, further make the network topology better match current situation and specified QoS requirements. Experimental results have demonstrated that proposed strategy can achieve less energy consumption, longer network lifetime, and better load balancing, especially for the cases with heterogeneous initial energy, nonuniform distribution, and higher density of nodes.
The Laccase‐Lig Multienzymatic Multistep System in Lignin Valorization
Authors: Vignali Elisa , Gigli Matteo , Cailotto Simone , Pollegioni Loredano , Rosini Elena , Crestini Claudia 
Published: August 2022

AbstractA laccase‐Lig multienzymatic multistep system for lignin depolymerization was designed and developed. Studies were performed on pristine and fractionated lignins (Kraft and Organosolv) using a specific cascade of enzymes, that is, laccases from Bacillus licheniformis and from Funalia trogii, respectively for Kraft and Organosolv lignin, followed by the Lig system from Sphingobium sp. SYK‐6 (β‐etherases Lig E and Lig F, glutathione lyase Lig G). Careful elucidation of the structural modifications occurring in the residual lignins associated with the identification and quantification of the generated low‐molecular‐weight compounds showed that (i) the laccase‐Lig system cleaves non‐phenolic aryl glycerol β‐O‐4 aryl ether bonds, and (ii) the overall reactivity is heavily dependent on the individual lignin structure. More specifically, samples with low phenolic/aliphatic OH groups ratio undergo net depolymerization, while an increased phenolic/aliphatic OH ratio results in the polymerization of the residual lignin irrespective of its botanical origin and isolation process.
Confined WS2 Nanosheets Tubular Nanohybrid as High‐Kinetic and Durable Anode for Sodium‐Based Dual Ion Batteries
Authors: Liu YangJie , Li Junwei , Liu Beibei , Chen Yuhua , Wu Yongmin , Hu Xiang , Zhong Guobao , Yuan Jun , Chen Junxiang , Zhan Hongbing , Wen Zhenhai 
Published: August 2022

AbstractSodium based dual‐ion battery (SDIB) has been regarded as one of the promising batteries technologies thanks to its high working voltage and natural abundance of sodium source, its practical application yet faces critical issues of low capacity and sluggish kinetics of intercalation‐type graphite anode. Here, a tubular nanohybrid composed of building blocks of carbon‐film wrapped WS2 nanosheets on carbon nanotube (WS2/C@CNTs) was reported. The expanded (002) interlayer and dual‐carbon confined structure endowed WS2 nanosheets with fast charge transportation and excellent structural stability, and thus WS2/C@CNTs showed highly attractive electrochemical properties for Na+ storage with high reversible capacity, fast kinetic, and robust durability. The full sodium‐based dual ion batteries by coupling WS2/C@CNTs anode with graphite cathode full cell presented a high reversible capacity (210 mAh g−1 at 0.1 A g−1), and excellent rate performance with a high capacity of 137 mAh g−1 at 5.0 A g−1.
HHV8‐negative primary effusion‐based large B‐cell lymphoma in a patient with chronic myeloid leukemia, BCR::ABL1‐positive under dasatinib treatment: Report of a new case and literature review
Authors: Christe Lucine , Veloza Luis , Gros Louis , Bisig Bettina , Blum Sabine , Hewer Ekkehard , de Leval Laurence 
Published: August 2022

AbstractDasatinib, a second‐generation tyrosine kinase inhibitor (TKI), used as treatment for chronic myeloid leukemia, BCR::ABL1‐positive (CML), is complicated by pleural or pericardial effusions in about one‐third of patients. Besides, in exceptional instances, effusion‐based neoplastic B‐cell lymphoproliferations have been described. Here, we report an HHV8‐negative, EBV‐positive large B‐cell lymphoma presenting as a pericardial effusion in a patient with CML treated with dasatinib for 23 months, without associated tumor mass or lymphadenopathies. Large tumor cells showed a B‐cell phenotype (CD20+, CD79+), with evidence of EBV infection (EBER‐ISH+), but HHV8 (LANA‐1) negative. Monoclonal IG gene rearrangements were identified. BCL2, BCL6, and MYC genes were not rearranged. Despite the aggressive cytomorphology the patient was in complete remission after 4 cycles of R‐CHOP after 8 months follow‐up. Four other cases of large B‐cell effusion‐based lymphomas developed in the setting of dasatinib therapy for CML have been reported in the literature. The four cases were HHV8‐negative and one case was EBV‐positive. Three of the four patients experienced a benign clinical course, which is in contrast to HHV8‐positive primary effusion lymphoma (PEL). The mechanisms of development of these effusion‐based B‐cell lymphoproliferations in patients receiving TKI are not completely elucidated. Acute or relapsing effusions during TKI treatment in the setting of CML should be cytologically examined to exclude clonal B‐cell lymphoproliferations.
Tooth transplantation and replantation: Biological insights towards therapeutic improvements
Authors: Ideno Hisashi , Komatsu Koichiro , Nakashima Kazuhisa , Nifuji Akira 
Published: August 2022

SummaryTransplantation and replantation of teeth are effective therapeutic approaches for tooth repositioning and avulsion, respectively. Transplantation involves transplanting an extracted tooth from the original site into another site, regenerating tissue including the periodontal ligament (PDL) and alveolar bone, around the transplanted tooth. Replantation places the avulsed tooth back to its original site, regenerating functional periodontal tissue. In clinical settings, transplantation and replantation result in favorable outcomes with regenerated PDL tissue in many cases. However, they often result in poor outcomes with two major complications: tooth ankylosis and root resorption. In tooth ankylosis, the root surface and alveolar bone are fused, reducing the PDL tissue between them. The root is subjected to remodeling processes and is partially replaced by bone. In severe cases, the resorbed root is completely replaced by bone tissue, which is called as “replacement resorption.” Resorption is sometimes accompanied by infection‐mediated inflammation. The molecular mechanisms of ankylosis and root resorption remain unclear, although some signaling mechanisms have been proposed. In this mini‐review, we summarized the biological basis of repair mechanisms of tissues in transplantation and replantation and the pathogenesis of their healing failure. We also discussed possible therapeutic interventions to improve treatment success rates.