bluuebunny/crossref_metadata_2025_split huggingface dataset:
Treatment patterns, healthcare resource use, and costs associated with uncomplicated urinary tract infection among female patients in the United States
Authors: Moon Rena C. , Marijam Alen , Mitrani-Gold Fanny S. , Gibbons Daniel C. , Kartashov Alex , Rosenthal Ning A. , Joshi Ashish V. 
Published: November 2022

Background
We evaluated associations between antibiotic prescription and healthcare resource use and costs (Part A), and between antibiotic switching and healthcare resource use, costs, and uncomplicated urinary tract infection recurrence (Part B) in female patients with uncomplicated urinary tract infection in the United States.

Methods
This retrospective cohort study of linked Optum and Premier Healthcare Database data included female patients ≥12 years old with an uncomplicated urinary tract infection diagnosis (index date), who were prescribed antibiotics during an outpatient/emergency department visit between January 1, 2013 and December 31, 2018. In Part A, patients were stratified by antibiotic prescription appropriateness: appropriate and optimal (compliant with Infectious Diseases Society of America 2011 guidelines for drug class/treatment duration) versus inappropriate/suboptimal (inappropriate drug class/treatment duration per Infectious Diseases Society of America 2011 guidelines, and/or treatment failure). In Part B, patients were stratified by treatment pattern (antibiotic switch vs no antibiotic switch). Healthcare resource use and costs during index episode (within 28 days of index date) and 12-month follow-up were compared.

Results
Of 5870 patients (mean age 44.5 years), 2762 (47.1%) had inappropriate/suboptimal prescriptions and 567 (9.7%) switched antibiotic. Inappropriate/suboptimal prescriptions were associated with higher healthcare resource use (mean number of ambulatory care and pharmacy claims [both p < 0.001]), and higher total mean cost (inpatient, outpatient/emergency department, ambulatory visits, and pharmacy costs) per patient ($2616) than appropriate and optimal prescriptions ($649; p < 0.001) (Part A). Antibiotic switching was associated with more pharmacy claims and higher total mean costs (p ≤ 0.01), and a higher incidence of recurrent uncomplicated urinary tract infection (18.9%) than no antibiotic switching (14.2%; p < 0.001) (Part B).

Conclusions
Inappropriate/suboptimal prescriptions and antibiotic switching were associated with high costs, ambulatory care, and pharmacy claims, suggesting a need for improved uncomplicated urinary tract infection prescribing practices in the United States.
Cyclic performance of moment connections with reduced beam sections using different cut-flange profiles
Authors: Al-Kannoon Muslim Abdul-Ameer , Al-Thabhawee Hayder Wafi 
Published: November 2022

Abstract
Reduced beam section (RBS) behaviours with various cut-flange configurations were investigated numerically in this study. A three-dimensional finite element model material non-linearity was built and validated experimentally, and the impacts of the cut--flange profile on the moment-rotation behaviour and ductility response of moment-resisting connections were investigated in a parametric form. Five-moment connections with various forms of decreasing beam flange were thus modelled using ABAQUS software and compared in terms of cyclic behaviour. RBS with circular, rectangular, trapezoidal, triangular, and drilled holes cut-flange configurations were adopted, and the finite element analysis results showed that radius cut RBS have uniform stress contours, while a re-entrant corner in rectangular, trapezoidal, or triangular cut-flange profiles’ connections may result in stress concentration, resulting in a fracture of the flange. In addition, the numerical testing showed that the RBS connection with a circular cut-flange profile offers a lower rupture index than other connections. Thus, the RBS created using circular cut-flange profiles dissipates more energy than other connections.
Using modified inverse distance weight and principal component analysis for spatial interpolation of foundation settlement based on geodetic observations
Authors: Beshr Ashraf A. A. , Kaloop Mosbeh R. 
Published: November 2022

Abstract
The article presents a novel computation technique for predicting the settlement of reinforcement concrete (R.C) raft foundations based on total station and precise leveling measurements. Modified inverse distance weight (MIDW) and principal component analysis (PCA) are developed to predict the nonmeasurable settlement of raft foundations and are compared to regression techniques. Wall measurements are used to verify the proposed interpolation methods. Six observation epochs were carried out over 3 years for the R.C raft foundation of a multistory building in Baltim, Egypt, which rests on clay soil, to monitor and predict the foundation settlement. The obtained results show that PCA and MIDW models outperform other models in interpolating nonmeasurable (invisible) points, while the accuracy of MIDW is the best. The developed techniques can be used to interpolate nonmeasurable (invisible) points to understand the actual behavior of foundation settlement. The monitoring building showed that the slope of the foundation in the X direction is 7.9 and 14.5% after 5 and 26 months, respectively.
Taxonomic reassessment of the chaco mice of the genus Andalgalomys Williams and Mares, 1978 (Rodentia, cricetidae) with a redefinition of Andalgalomys olrogi Williams and Mares, 1978
Authors: Quatrocchi Maira , Ojeda Agustina A. , Teta Pablo 
Published: November 2022

Abstract
The genus Andalgalomys Williams and Mares, 1978 includes three species of small phyllotine rodents: Andalgalomys olrogi Williams and Mares, 1978; Andalgalomys pearsoni (Myers, 1977); and Andalgalomys roigi Mares and Braun, 1996. These mice are distributed from southeastern Bolivia and western Paraguay to west-central Argentina, occupying mostly semi-desert environments, such as the Dry Chaco and High Monte. Available phylogenetic analysis of DNA sequences suggests that Andalgalomys olrogi and Andalgalomys roigi, which also share the same diploid complement, constitute the same species. We tested this hypothesis through a qualitative and quantitative morphological approach, in order to integrate different lines of evidence. Based on the largest sample analyzed to date, we found that some of the supposedly diagnostic traits of both Andalgalomys olrogi and Andalgalomys roigi (e.g., dorsal coloration) are more variable than previously documented. In addition, principal component analysis failed to separate Andalgalomys olrogi from Andalgalomys roigi in the multivariate space, although clearly segregate Andalgalomys pearsoni from these two taxa. Based on these findings, plus previous evidence, we consider Andalgalomys roigi as a junior synonym of Andalgalomys olrogi.
Porcupines in Italian islands: update on the distribution of Hystrix cristata in Sardinia
Authors: Milana Giuliano , Viviano Andrea , Mori Emiliano 
Published: November 2022

Abstract
In the last few decades, the crested porcupine (Hystrix cristata L., 1758) showed a remarkable range expansion in Italy, due to legal protection, climatic change and antropochorous releases. Particularly, porcupines have been released also in Sardinia, with first records of this large rodent in the wild dating back to 2005. Historical and social factors related to the progressive urbanization and the consequent abandonment of the traditional land use in mountain landscapes probably helped the re-expansion of forest, uncultivated fields and of animal’s species associated with these habitats. In Sardinia, a population establishment and a subsequent expansion of the area of distribution can be predicted as large portions of the island are highly suitable for the crested porcupine. Therefore, this recently introduced population should be removed to limit potential ecological and social conflicts.
Secret information security system in computer network based on Bayesian classification and nonlinear algorithm
Authors: Wu Hao 
Published: November 2022

Abstract
To solve the problem that most computer network security assessment systems cannot comprehensively analyze data, this article proposes a research method for computer network confidentiality information security system based on the Bayesian classification algorithm. This research takes the computer network security secret-related information security as the core, cleverly uses the EBCA back-propagation model, and comprehensively uses nonlinear functions to propose a computer network secret-related information security application system considering EBCA, which effectively solves the complex cross-linking relationship. The effectiveness of the method is verified by simulation experiments. Simulation experiments show that when the network performance is in the optimal state, the slope is 1, the intercept is 0, and the fitting degree is 1. The method proposed in this article is especially suitable for the nonlinear characteristics of computer network security and can accurately, comprehensively, and systematically reflect the security operation status of network security and confidential information. Then, through the simulation test, it is found that the method in this study can effectively meet the error requirements of equipment integrity and equipment normal rate.
Frequency of Multiple Modals with Might on the Web
Authors: Cehan Nadina 
Published: November 2022

Abstract
The paper investigates multiple modals such as might could, might would, might can and would might. These are just a few of the core modal combinations with might which are being looked at through the use of iWeb and GloWbE, two corpora of online texts. The research primarily reveals the multiple modals’ frequency in the corpora. It also shows that they are found in both American and British English. In addition, their negation and inversion patterns are displayed.
Person and Empathetic Deixis in the Institutional Discourse
Authors: Niţă Oana-Maria Puiu 
Published: November 2022

Abstract
The paper explores the use of person and empathetic deixis in the institutional discourse within an interdisciplinary landscape. It underpins a corpus-based approach, focusing on texts on COVID19 pertaining to the World Health Organization. Our aim is to demonstrate that deictic pronominals have collective self-reference, expressing solidarity and empathy.
Dorothea Tanning’s Reimagining of the Maternal
Authors: Glăvan Gabriela 
Published: November 2022

Abstract
Dorothea Tanning’s longstanding interest in the maternal element completes the artist’s complex relationship to femininity and the female experience, turning them into essential themes in her oeuvre. I shall explore the particular manner in which the American Surrealist integrates and transforms the notion of motherhood in her art. I shall also argue that Tanning’s works as a writer offer an original insight into this cardinal theme in western art, as she dismantles common tropes and refashions them into a new, unusual language.
The Binomials and Multinomials in two English Translations of the Lotus Sutra (Chapter Two)
Authors: Zhao Qian 
Published: November 2022

Abstract
The Lotus Sutra, an important Buddhist classic, is strongly rhetorical with its frequently used binomials (word pairs). This paper studies its two most recent English translations by Watson (1993) and Reeves (2008), the second chapter in particular, and conducts comparative research into the formal, etymological, semantic, sequential and other distinct properties of the binomials and multinomials employed by different translators.
Americana bei Jean Bodin und Johann Fischart, Hexen bei Jean de Léry
Authors: Perplies Helge 
Published: November 2022

Abstract
The scope of Early Modern Demonology is universal, for the perceived threat of the devil is omnipresent, stretching through time and space. This article examines various utilizations of the description of central and south American indigenous peoples in demonological discourse. By means of three closely related examples, I will demonstrate the discursive conflation of deviant behavior in Europe and in America through comparisons and transferences: Jean Bodin’s Démonomanie des Sorciers (1580), its German translation by Johann Fischart (1581/1586), and Jean de Léry’s writings, especially his Histoire d’un voyage (1578/1585). Within this discursive nexus, Léry compares the American Indigenes to European Catholics, whereas Bodin compares them to European witches - and Fischart completes this argumentative triangle by calling for European Catholics to be held accountable for comparable acts in the same way as European witches.
Gustav Freytags lateinische Qualifikationsschriften De initiis scenicae poesis apud Germanos (1838) und De Hrosuitha poetria (1839)
Authors: Walser-Bürgler Isabella 
Published: November 2022

Abstract
The article investigates Gustav Freytag’s dissertation De initiis scenicae poesis apud Germanos [On the beginnings of dramatic poetry in Germany] and his habilitation De Hrosuitha poetria [On the poetess Hrotsvitha], written and published in 1838 and 1839, respectively. Usually disregarded in analyses of Freytag’s oeuvre as insignificant minor texts or pointless Latin writings among his otherwise exclusively German historiographical and literary production, they serve, in a nutshell, as early comprehensive samples of his life-long approach to cultural historiography and German literature. More precisely, one could term them the ›groundwork‹ constitutive for many of his later efforts as a historian and author. Apart from dissecting Freytag’s qualification papers in this respect for the first time, the article also expands on the institutional framework of early nineteenth-century university education in Germany and its upheld practice of Latin scientific discourse.
Philanthropische Inklusionen: Gemeinnützige Stiftungen in der Gesellschaft
Authors: Moser Evelyn 
Published: November 2022

ZusammenfassungPrivate, gemeinnützige Stiftungen sind nicht nur in allen Bereichen der modernen Gesellschaft präsent, sondern auch ein sichtbarer Gegenstand öffentlicher Debatten und umfangreicher sozialwissenschaftlicher Forschung. Gesellschaftstheoretische Zugriffe, die der facettenreichen Einbettung von Stiftungen in ihre sozialen Kontexte gerecht werden, fehlen bislang. Dieser Beitrag setzt an diesem Desiderat an und lotet das Potenzial einer inklusionstheoretischen Perspektive aus. In einer dreiteiligen, explorativen Skizze untersucht er, wie sich Stiftungen in unterschiedliche gesellschaftliche Inklusionsverhältnisse einfügen, welche Effekte ihre Tätigkeiten auf die Adressierbarkeit von Personen im Stiftungsumfeld haben und welche sozialen Rollen im Kontext von Stiftungen entstehen. Der erste Skizzenteil widmet sich den Ursprüngen moderner Stiftungen in der stratifizierten Gesellschaft des christlichen Mittelalters. Der zweite Teil rekonstruiert das spezielle Verhältnis von Stiftungen und Politik, das sich mit der Ausrichtung auf das Gemeinwohl in der frühen Neuzeit andeutete und bis in die Gegenwart prägend ist. Der dritte Teil blickt auf die Einbettung von Stiftungen in die Inklusionsverhältnisse gesellschaftlicher Funktionssysteme jenseits der Politik.
Dokumentieren als kommunikative Form im Medium der Darstellung
Authors: Bohn Cornelia 
Published: November 2022

Zusammenfassung
Der Beitrag schlägt eine Erweiterung der Medien- und Kommunikationstheorie Luhmanns um einen Medientyp vor, den ich als Darstellungsmedien bezeichne. Der Text kombiniert einen Theorievorschlag mit historisch semantischen Rekonstruktionen. Dazu werden die Konzepte Medium und Form, Prämissen ereignisbasierter Sozialtheorien sowie Konzepte und historische Semantiken des Darstellens aufeinander bezogen. Ausgangspunkt und Exemplum des Artikels bildet das konkrete Phänomen des Dokumentierens als kommunikativer Form im Horizont der gegenwärtig in der Digitalisierung angekommenen unabschließbaren Morphogenese von Kommunikationsmedien und -formen. Um die soziologische Reichweite des Phänomens zu verdeutlichen, werden Semantiken des Dokumentierens vorgestellt, die sich in höchst unterschiedlichen gesellschaftlichen Feldern wie Organisationen und Administrationen, moderne Wissenschaft, Publikationswesen und Wissensvermittlung, Personenidentifikation und der modernen Kunst herausgebildet haben.
Direct-acting antiviral therapy may help restore HCV-induced impaired redox balance and liver fibrosis process
Authors: Bal Tayibe , Doğan Serdar , Özcan Oğuzhan , Çabalak Mehmet , Çirkin Berfin 
Published: November 2022

Abstract

Objectives
The aim of this study was to investigate the changes in thiol/disulfide balance, pro-fibrotic mediators (transforming growth factor-beta [TGF-β] and periostin) and a potential biomarker for the prediction of HCV-induced HCC (3β-hydroxysterol Δ24-reductase [DHCR24]) during direct-acting antiviral (DAA) therapy in chronic hepatitis C (CHC) patients.

Methods
This prospective cohort study included 56 non-cirrhotic, treatment-naive CHC patients who were treated with DAAs between January and June 2020. Laboratory tests, including serum total/native thiol, TGF-β

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periostin, DHCR24, total bilirubin and albumin levels were measured and disulfide levels were calculated at baseline, then at 1 month and at the end of therapy (EOT).

Results
Of the 56 patients, all achieved a sustained virological response after DAA therapy. There was a significant decrease in serum levels of disulfide and TGF-β, (p=0.020 and p<0.001, respectively) and a significant increase in serum levels of native thiol compared with baseline levels (p=0.010). There was no significant change in levels of total thiol, DHCR24 and periostin levels. Serum TGF-β levels were found to be positively correlated with total bilirubin levels (rs=0.470, p=0.001) and negatively with albumin levels (rs=−0.483, p<0.001). A significant moderate positive correlation was determined between baseline serum DHRC24 and disulfide levels (rs=0.356, p=0.007).

Conclusions
The study results suggest that the DAA therapy may help to restore the impaired thiol/disulfide balance and reduce the pro-fibrotic process in CHC patients by markedly decreasing serum levels of TGF-β, a key player in HCV-induced liver fibrosis.
4f-ЛЮМІНЕСЦЕНЦІЯ В 3d-4f ГЕТЕРОЯДЕРНИХ КОМПЛЕКСАХ ПОРФІРИНІВ
Authors: Семенішин Микола М. , Смола Сергій С. , Русакова Марія Ю. , Русакова Наталія В. 
Published: November 2022

На основі дитопних порфіринів, структура яких дозволяє отримувати різноманітні гетерометалічні комплекси, отримано сполуки порфіринів з Nd(III), Yb(III) та Cu(II), Zn(II), Pd(II). Зазначені f-метали були обрані через те, що інфрачервона люмінесценція цих іонів металів може бути сенсибілізована порфіринами, а, з іншого боку, представлені іони d-металів мають різний вплив на порфіриновий хромофор. Фотосенсибілізована 4f-люмінесценція в ближній інфрачервоній області та молекулярна флуоресценція у видимій області гетероядерних 3d-4f комплексів надзвичайно чутливі до природи іонів d- та f-металів. Так, у випадку вільних порфіринових ядер і комплексів з Zn(II) характерна ефективна молекулярна флуоресценція (квантовий вихід 4–11 %). Крім того, для цих цих сполук характерні три типи випромінювання одночасно – це флуоресценція, фосфоресценція та 4f-люмінесценція і нами було встановлено, що ефективність всіх видів емісії та значення максимумів їх смуг не залежать від природи периферичних хелатних фрагментів. Флуоресценція комплексів купруму та паладію майже повністю погашена, але Pd(II)-порфірин виконує роль 4f-сенсибілізатора на відміну від Cu(II)-порфірину. Розглянуто вплив кисню на люмінесценцію комплексів і виявлено, що лише комплекси Pd-Nd чутливі до його присутності – деоксигенація призводить до 20 % підвищення ефективності 4f-люмінесценції.
ВПЛИВ АНІОНІВ НЕНАСИЧЕНИХ ОРГАНІЧНИХ КИСЛОТ НА ПРОЦЕС ЕЛЕКТРООКИСНЕННЯ АКВАКОМПЛЕКСІВ МАНГАНУ (ІІ)
Authors: Варгалюк Віктор Ф. , Середюк Володимир А. , Плясовська Катерина А. , Кучай Ігор М. 
Published: November 2022

З використанням методів квантово-хімічного моделювання досліджено вплив ненасичених двоосновних органічних кислот на термодинамічні характеристики реакції одноелектронного окиснення ацидоаквакомплексів Mn2+, які визначають базовий рівень енергоефективності процесу електрохімічного синтезу MnO2. Показано, що монодентатні аніонні форми малеїнової (НМ–) та фумарової (HF–) кислот не мають будь-яких переваг відносно аніонів монокарбонових кислот, зокрема, – ацетат-йонів. Навіть навпаки, утворення водневих зв’язків з внутрішньосферними молекулами води другою карбоксильною групою, яка не зв’язана з центральним атомом, суттєво погіршує ефективність впливу аніонів НМ– i HF– на стадію вилучення електрона з комплексів [Mn2+(L)(H2O)5]. Величина стандартного редокс-потенціалу E0(Mn2+/Mn3+) йонних систем з однозарядними аніонами малеїнової і фумарової кислот становить 1.05 В і 0.99 В відповідно, що значно перевищує E0(Mn2+/Mn3+) ацетатних комплексів (0.66 В), наразі рекомендованих до практичного використання. Присутність у внутрішній координаційній сфері ацидоаквакомплексів Mn2+ бідентатно зв’язаного двозарядного аніона малеїнової кислоти зменшує E0(Mn2+/Mn3+) до 0.32 В, а це вдвічі менше, ніж в ацетатному електроліті. Перспективність малеїнатних електролітів посилюється також здатністю ненасичених аніонів М2– каталізувати стадію диспропорціонування комплексів Mn3+.
Effects of a group using digital technologies and physical activity on cognition and health of the elderly
Authors: Silva Leonardo Henrique da , Campos Lucas Wibelinger de , Chicon Patrícia Mariotto Mozzaquatro , Garces Solange Beatriz Billig , Krug Marilia de Rosso , Xavier André Junqueira , Krug Rodrigo de Rosso 
Published: November 2022

Aim: to estimate the effects of a group using digital technologies and physical activity on cognitive function and health variables in the elderly. Methods: intervention research with 29 elderly men (n=7) and women (n=22), all from the University of Cruz Alta community. The intervention consisted of a Program to use digital technologies and practice physical activity (walking). It had weekly meetings (total of 16 meetings) of approximately 90 minutes, first using digital technologies – computers and internet (approximately 60 minutes) and then walking (30 minutes). Cognitive function was measured by the Mini Mental State Examination. Sex, age, marital status, education, disease diagnosis, vision problems, medication, use of tobacco and alcohol and functional capacity were also collected through a questionnaire. The Body Mass Index was also checked. Participants were assessed before and after the program. The data were analyzed by paired Student’s t-test with a 5% probability. Results: it was evident that the proposed program improved cardiorespiratory fitness (519.14 pre-test - 583.86 post-test, p = 0.005) and cognitive ability (25.90 pre-test - 26.21 post-test, p> 0.001) of participants, in addition to influencing the cessation of tobacco use (20.7%). Conclusion: these results show the importance of programs aimed at the cognitive improvement of elderly people, and health variables, considering that these can and should be inserted in health care settings.