bluuebunny/crossref_metadata_2025_split huggingface dataset:
Status quo and problem analysis of cervical cancer screening program in China: Based on RE-AIM framework
Authors: Zhu Jingfen , Ge Zhenghao , Xia Jiawei , Liu Qi , Ran Qingqing , Yang Yongbin 
Published: October 2022

BackgroundAn organized cervical cancer screening program is an effective method to prevent and control cervical cancer. This study aims to find barriers and facilitators in the implementation process of National Cervical Cancer Screening Program in Rural Areas (NACCSPRA) in China through program evaluation, and thus propose suggestions for optimization of the program.MethodsThrough stratified sampling, 8 provinces (autonomous cities/districts) in eastern, southern, western, northern, and central China were selected for evaluation of NACCSPRA based on the RE-AIM framework. We obtained 15 program providers' experience and perspectives through semi-structured interviews. The data was analyzed using a combination of deductive and inductive analysis methods.ResultsThe study found that NACCSPRA mainly serves women with rural household registration or urban minimum living guarantee. Population mobility and certain demographic characteristics such as low education and poor health awareness are common participation barriers, while program publicity acts as a facilitator. A screening program's direct benefit is to promote early detection and treatment of cervical cancer, and its perceived indirect effect is to raise people's health awareness. The proportion of regions adopting the project is relatively high, and factors affecting employees' participation are screening workload, working environment, welfare benefits, degree of preference for grassroots work, and whether the project is included in the performance appraisal; In terms of implementation, there are disparities in screening methods, network informatization levels, and capital investment in various regions. Poor development of screening information system and insufficient screening funds are significant barriers to improvement of project implementation. In contrast, the overall implementation of follow-up is better; related policies issued by the local government and financial subsidies for poor women ensure the maintenance of the project.ConclusionShortage of funds is an important problem faced by current screening project, which negatively influences upgrade of cervical cancer prevention strategy, implementors' working environment, and impedes improvement of information network. In addition, defects in population coverage, especially in mobile population also deserves attention. The study found barriers and facilitators of NACCSPRA perceived by project providers and provided a theoretical foundation for project optimization.
Self-collection of capillary blood and saliva to determine COVID-19 vaccine immunogenicity in patients with immune-mediated inflammatory diseases and health professionals
Authors: Schmetzer Caroline , Vogt Ekaterina , Stellar Laura , Godonou Elie-Tino , Liphardt Anna-Maria , Muehlensiepen Felix , Vuillerme Nicolas , Hueber Axel J. , Kleyer Arnd , Krönke Gerhard , Schett Georg , Simon David , Knitza Johannes 
Published: October 2022

IntroductionBeing able to independently determine vaccine induced antibody responses by minimal-invasive methods is of great interest to enable a flexible and effective vaccination strategy. This study aimed to evaluate (1) the accuracy, feasibility, usability and acceptability of capillary blood and saliva self-sampling to determine SARS-CoV-2 antibody responses in patients with immune-mediated inflammatory diseases (IMIDs) and health professionals (HP).MethodsIMID patients and HP having received two doses of SARS-CoV-2 vaccines, self-collected capillary blood (Tasso+) and saliva samples. Capillary samples were considered interchangeable with venous blood if three criteria were met: Spearman's correlation coefficient (r) &gt; 0.8, non-significant Wilcoxon signed-rank test (i.e., p &gt; 0.05), and a small bias or 95% of tests within 10% difference through Bland-Altman. Participants completed a survey to investigate self-sampling usability (system usability scale; SUS) and acceptability (net promoter score; NPS). Study personnel monitored correct self-sampling completion and recorded protocol deviations.Results60 participants (30 IMID patients and 30 HP) were analyzed. We observed interchangeability for capillary samples with an accuracy of 98.3/100% for Anti-SARS-CoV-2 IgG/IgA antibodies, respectively. Fifty-eight capillary blood samples and all 60 saliva samples were successfully collected within the first attempt. Usability of both self-sampling procedures was rated as excellent, with significantly higher saliva ratings (p &lt; 0.001). Capillary self-sampling was perceived as significantly (p &lt; 0.001) less painful compared to traditional venous blood collection. Participants reported a NPS for capillary and saliva self-sampling of +68% and +63%, respectively. The majority of both groups (73%) preferred capillary self-sampling over professional venous blood collection.ConclusionOur results indicate that capillary self-sampling is accurate, feasible and preferred over conventional venous blood collection. Implementation could enable easy access, flexible vaccination monitoring, potentially leading to a better protection of vulnerable patient groups. Self-collection of saliva is feasible and safe however more work is needed to determine its application in clinical practice.
Effects of nordic walking exercise on gait, motor/non-motor symptoms, and serum brain-derived neurotrophic factor in individuals with Parkinson's disease
Authors: Harro Cathy C. , Shoemaker Michael J , Coatney Cassandra M. , Lentine Valerie E. , Lieffers Lillian R. , Quigley Jessica J. , Rollins Shannon G. , Stewart Jonathan D. , Hall Julie , Khoo Sok Kean 
Published: October 2022

ObjectiveThe primary purpose of this study was to investigate the immediate and long-term effects of Nordic Walking (NW) exercise on walking function, motor/non-motor Parkinson's Disease (PD) symptoms, and serum brain-derived neurotrophic factor (BDNF) in persons with idiopathic PD.MethodsTwelve community-dwelling participants with mild to moderate idiopathic PD and varied degrees of gait dysfunction were recruited for this prospective, repeated measures design that examined clinical measures and BDNF levels at baseline (T0), post-intervention (T1) and 3-month follow-up (T2). Participants engaged in 6 weeks of supervised NW exercise training with individualized instruction, followed by 14 weeks of independent NW exercise with remote coaching. Outcome measurements included daily step counts, 6-Minute Walk Test (6-MinWT), 10-Meter Walk Test (10MWT), spatiotemporalparameters, Timed Up and Go Test (TUG), dual-task TUG, Revised-Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS), Revised-Freezing of Gait Questionnaire, MDS-Nonmotor Symptom scale (NMS), Parkinson's Fatigue Scale, and serum BDNF levels. The Friedman test with post hoc Wilcoxon sign-ranked pairwise comparisons were used to compare baseline to T1, baseline to T2, and T1 to T2 timepoints with a Benjamini-Hockberg correction applied.ResultsStatistically significant improvements found post-training and retained at 3-month follow-up included 6-MinWT, daily step count, 10mWT, MDS-UPDRS, and TUG with effect sizes of 0.57 to 1.03. Serum BDNF at T2 was significantly greater than T0 and T1. Although no statistically significant improvements were observed in the MDS-NMS, 9 of 12 participants had improved non-motor symptoms. There was good adherence, sustained independent exercise engagement, and no adverse events over the 5-month study duration.ConclusionsThis study demonstrated that NW exercise was a safe, feasible, and sustainable mode of aerobic exercise for this sample of participants with varied Parkinson's disease duration and severity. Following an individualized and progressive NW training intervention, significant improvements in walking function, daily activity level, and motor function were observed. Following the supervised NW training phase, independent three-month engagement in NW exercise was sustained with long-term retention of these clinical improvements and an increase in serum BDNF levels over this five-month NW exercise trial.ImpactNordic walking exercise may be a safe, feasible and sustainable mode of independent exercise for improving daily ambulatory activity, gait and motor function, and serum BDNF in individuals with mild to moderate PD with varied gait abilities.Clinical Trials Registry ID20-101-H
Monitoring and Cordoning Wildfires with an Autonomous Swarm of Unmanned Aerial Vehicles
Authors: Saffre Fabrice , Hildmann Hanno , Karvonen Hannu , Lind Timo 
Published: October 2022

Unmanned aerial vehicles, or drones, are already an integral part of the equipment used by firefighters to monitor wildfires. They are, however, still typically used only as remotely operated, mobile sensing platforms under direct real-time control of a human pilot. Meanwhile, a substantial body of literature exists that emphasises the potential of autonomous drone swarms in various situational awareness missions, including in the context of environmental protection. In this paper, we present the results of a systematic investigation by means of numerical methods i.e., Monte Carlo simulation. We report our insights into the influence of key parameters such as fire propagation dynamics, surface area under observation and swarm size over the performance of an autonomous drone force operating without human supervision. We limit the use of drones to perform passive sensing operations with the goal to provide real-time situational awareness to the fire fighters on the ground. Therefore, the objective is defined as being able to locate, and then establish a continuous perimeter (cordon) around, a simulated fire event to provide live data feeds such as e.g., video or infra-red. Special emphasis was put on exclusively using simple, robust and realistically implementable distributed decision functions capable of supporting the self-organisation of the swarm in the pursuit of the collective goal. Our results confirm the presence of strong nonlinear effects in the interaction between the aforementioned parameters, which can be closely approximated using an empirical law. These findings could inform the mobilisation of adequate resources on a case-by-case basis, depending on known mission characteristics and acceptable odds (chances of success).
Experimental Investigation of Reynolds Number and Spring Stiffness Effects on Vortex-Induced Vibration Driven Wind Energy Harvesting Triboelectric Nanogenerator
Authors: Chang Qing , Fu Zhenqiang , Zhang Shaojun , Wang Mingyu , Pan Xinxiang 
Published: October 2022

Vortex-induced vibration (VIV) is a process that wind energy converts to the mechanical energy of the bluff body. Enhancing VIV to harvest wind energy is a promising method to power wireless sensor nodes in the Internet of Things. In this work, a VIV-driven square cylinder triboelectric nanogenerator (SC-TENG) is proposed to harvest broadband wind energy. The vibration characteristic and output performance are studied experimentally to investigate the effect of the natural frequency by using five different springs in a wide range of stiffnesses (27 N/m<K<90 N/m). The square cylinder is limited to transverse oscillation and experiments were conducted in the Reynolds regime (3.93×103–3.25×104). The results demonstrate the strong dependency of VIV on natural frequency and lock-in observed in a broad range of spring stiffness. Moreover, the amplitude ratio and range of lock-in region increase by decreasing spring stiffness. On the other hand, the SC-TENG with higher spring stiffness can result in higher output under high wind velocities. These observations suggest employing an adjustable natural frequency system to have optimum energy harvesting in VIV-based SC-TENG in an expanded range of operations.
Using mathematics game-based intervention on children with special educational needs: Preliminary findings
Authors: Lilia Marcelino  , Conceição Costa  , Carlos Santos  
Published: October 2022

Many video games incorporate positive learning principles, stimulating students' cognitive functioning and promoting problem-solving and spatial abilities. The high levels of engagement and involvement that some students can achieve with video games are notable. Hence, video games for children with a long history of school failure, such as children with special educational needs (SEN). Moreover, it may give educators immediate and ongoing assessment of students' progress. When complemented with human tutoring, video games as a game-based intervention may improve mathematics performance since instruction is more effective when adapted to students' learning needs and pace.
As part of the research project "GBl4deaf – Game-based Learning for Deaf Students (PTDC/COM-CSS/32022/2017), the video game "Space adventure: Defend the planet!" was designed to stimulate arithmetic competencies in deaf and hearing children. The player must use elementary arithmetical and spatial concepts to rebuild an abandoned space station. Each challenge has three difficulty levels. In the game challenge used in this study, the player must add or remove particles to collect resources. The current research focuses on two questions: The study follows two research questions: Q1: Did the students make any progress in mathematics achievement after playing the video game?; Q2: Is the gameplay of Space adventure: Defend the planet! an engaging experience for players? A pre-and post-game mathematical test was applied to measure mathematics achievement and an observational grid to gather information about arithmetical procedures. Ten fourth- to ninth-graders participated in the study - four girls and six boys, aged between 9 and 16, three deaf and seven hearing students with different special needs (dyscalculia, cognitive deficits, autism spectrum disorder, deafness and Asperger syndrome). Due to the COVID-19 pandemic lockdown, children played the video game using Zoom video conference software in 8-12 sessions (50 minutes, two a three times/week). The results show 4% to 19% of mathematics progression after children played the video game and indicate that they maintain the use of counting-based procedures throughout the game sessions. For instance, they kept counting both addends starting from 1 or counting by 1, 2, 5 or 10 using a number line. The current data suggest that the videogame "Space adventure: Defend the planet!" allows educators to gather immediate information about students' difficulties and progression.
The Contribution of Game-based learning: Children with Autism Spectrum Disorder and Dyscalculia
Authors: Pradiante Vera 
Published: October 2022

This paper explores the potential of games to mathematics learning and promotion of globalpsychomotricity, relational/social skills in children with Autism Spectrum Disorder (ASD) and/or Dyscalculia students of Basic Education in Portugal. Inspired by Space Adventure: Defend the Planet! (SADP), an educational research-based game to children&#39;s primary mathematics’ learning [PTDC/COM-CSS/32022/2017], a game-based intervention was created to psychomotricity sessions at school facilities. The study was conducted by the researcher, Superior Technician of SEN and Rehabilitation. A mixed method approach is used to research: what impact does the intervention have on participants&#39; motivation, engagement, learning of mathematics and development of participants? Five schools in Portugal participated in the study, between December 2021 and March 2022, with 12 sessions, one session/week, 45 minutes. The sample: 19 participants: 12 boys, 9 with ASD and 3 with Dyscalculia; 7 girls, 2 with ASD and 5 with Dyscalculia. The average age is M=8.6 with SD=1.8. Prior to the intervention, the following instruments were applied: pre-tests of math skills, communication and social interaction, receptive and expressive language; Childhood Autism RatingScale; a Battery Movement Assessment Battery for Children; questionnaire Technologies/Video Games and Questionnaire of Support Measures for Learning and Inclusion. During the intervention, an observation grid and alternative communication materials were used per session. A PC, the SADP, gymnasium/relaxation room with a chair, table and gym supplies. From the results, computers, tablets, and mobile phones are the most frequently used by children. GRID/ABC Autism, Bini ABC/Human Body, and Minecraft/Troll are video games often played by participants. One girl aged 12 explained to the researcher how to create worlds on Minecraft, which is an indicator that “good” video games could be beneficial for ASD. “I feel free to explore my imagination!”- she said. Most children expressed rich verbalizations about SADP: “I love it”, “This game is interesting”. As preliminary results children were motivated, participative, engaged with learning math, and able to co-create motor activities inspired by SADP challenges. The data analysis of the present study is in progress and will be presented.
Visualization, Serious Games and Decision Making
Authors: Flores Benitez Alejandro , Medina Herrera Linda , Pacheco Ernesto , Molina Espinosa José Martín 
Published: October 2022

One of the most important objectives of serious games is to detonate behavioral changes of participants. Serious games generate engagement, they are meaningful, entertaining, and immersive. However, when the game represents a complex system, it contains a great number of variables and the relationship between its decision components are not entirely clear. Consequently, it is necessary to offer a set of tools that increase the data visualization of the players and help in the decision-making process must be provided. In our university, logistics professors have designed a simulator for logistics decision making. On the one hand, the game has gained acceptance from the student community, but on the other hand, several students do not accomplish a satisfactory performance. Therefore, these students fail to notice lots of variable interrelationships in the game, and they do not develop the skill required to follow a good decision-making process. The goal is two folded. On the one hand, the improvement of the participant's comprehension of a complex logistical system must be reached. On the other hand, the clarity on the decision-making process has to be laid out. A set of visualization support tools were created to accomplish those objectives. Neither of the tools aim to influence the decision-making process nor to show decision alternatives to the participant, but to highlight a few key performance indicators, constraints, and data that the students can use when making the decisions. In this paper it is presented how the participants have improved their understanding about the logistic system represented in the game, when the support tools are used. Moreover, their motivation has increased, they are more involved and committed to learn. Overall, their decision-making strategies have been modified and they have shown a better comprehension of the game structure. This paper contributes to underline the importance of visualization in student's learning, considering that currently big data, industry 4.0, as well as internet of things have gained a significant relevance in our everyday life. The design of strategic games involving these new variables are necessary. The more complex a system, the greater the number of visualization tools to strengthen the comprehension of the system are required.
Industri Tahu Rakyat dalam Tinjauan Life Cycle Assessment
Authors: Harjanto Taufan Ratri , Khasanah Mustafidatul , Putri Arsita Nur Rizkia 
Published: October 2022

Tofu is a type of food that is preferred and widely produced by Indonesian people. The existence of the tofu industry will have an impact on the quality of the environment. To reduce this impact, an analysis related to the Life Cycle Assessment (LCA) is required. The research aims to determine eco-friendly tofu products and the part of the process that has a high potential to pollute the environment in the micro tofu industry. The research method uses a cradle-to-gate approach, which focuses on the processing of raw materials into products in the form of white tofu and fried tofu. The stages of this research are based on SNI ISO-14040: goal and scope, inventory analysis, life cycle impact assessment, and interpretation. The results showed that fried tofu has a high potential to pollute the environment compared to white tofu, namely the contribution value of white tofu is 0.121 pt and the contribution value of fried tofu is 2.83 pt, this is based on the highest value on important issues (hotspots) related to the impact category, namely global warming potential is 154 kg CO2(eq), ozone depletion potential is 1.43.10-5 kg ​​CFC-11(eq), acid rain potential is 3.83.103 kg SO2(eq), eutrophication potential is 145 kg PO4 P-lim , energy use is 154 kg CO2(eq), and human health is 0.822 DALY. Based on the contribution analysis, hotspots on the results of the life cycle assessment of the micro tofu industry are in the frying process and the procurement of the main raw material used, soybeans. Alternative improvements can be made by changing the main ingredient of soybean seed into soybean slurry and replacing palm oil with soybean oil in frying firewood into biogas.
Modeling Reconfigurable Intelligent Surfaces-aided Directional Communications for Multicast Services
Authors: Chukhno Nadezhda 
Published: October 2022

<p>According to the 6G vision, the evolution of wireless communication systems will soon lead to the possibility of supporting Tbps communications, as well as satisfying, individually or jointly, a plethora of other very stringent quality requirements related to latency, bitrate, and reliability. The achievement of these goals will naturally raise many research issues within radio communications. In this context, a promising 6G wireless communications enabler is the reconfigurable intelligent surface (RIS) hardware architecture, which has already been recognized as a game-changing way to turn any naturally passive wireless communication setting into an active one. This paper investigates RIS-aided multicast 6G communications by first modeling the system delay as a first-come-first-served (FCFS) M/D/1 queue and analyzing the behavior under different blockage conditions. Then the study of multi-beam operation scenarios, covering multicast and RIS-aided multicast communications, is conducted by leveraging an M/D/c queue model. Achieved results show that large-size RISs outperform even slightly obstructed direct BS-to-user paths. In contrast, RISs of smaller sizes require the design of sophisticated power control and sharing mechanisms to achieve better performance.</p>
A LabVIEW Interface for RehaStim 2
Authors: RaviChandran Narrendar , Aw Kean , McDaid Andrew 
Published: October 2022

<p>Hasomed’s RehaStim 2 is a widely used stimulator for neurorehabilitation research. Using the serial communication protocol - <em>ScienceMode2, </em>direct hardware-level control of the stimulator is realized. This protocol facilitates bidirectional communication between a PC and the stimulator that enables the testing of novel stimulation strategies. By utilizing this communication protocol, the aim of this work is to demonstrate a similar hardware-level control through LabVIEW’s virtual instrumentation platform. Additionally, the LabVIEW-based implementation is made openly available for researchers to leverage the full potential of the stimulator for research applications. </p>