bluuebunny/crossref_metadata_2025_split huggingface dataset:
mHealth-Supported Gender- and Culturally Sensitive Weight Loss Intervention for Hispanic Men With Overweight and Obesity: Single-Arm Pilot Study
Authors: Garcia David O , Valdez Luis A , Aceves Benjamin , Bell Melanie L , Rabe Brooke A , Villavicencio Edgar A , Marrero David G , Melton Forest , Hooker Steven P 
Published: September 2022

Background
Hispanic men have disproportionate rates of overweight and obesity compared with other racial and ethnic subpopulations. However, few weight loss interventions have been developed specifically for this high-risk group. Furthermore, the use of mobile health (mHealth) technologies to support lifestyle behavior changes in weight loss interventions for Hispanic men is largely untested.

Objective
This single-arm pilot study examined the feasibility and acceptability of integrating mHealth technology into a 12-week gender- and culturally sensitive weight loss intervention (GCSWLI) for Hispanic men with overweight and obesity.

Methods
A total of 18 Hispanic men (mean age 38, SD 10.9 years; mean BMI 34.3, SD 5.5 kg/m²; 10/18, 56% Spanish monolingual) received a GCSWLI, including weekly in-person individual sessions, a daily calorie goal, and prescription of ≥225 minutes of moderate-intensity physical activity per week. mHealth technology support included tailored SMS text messaging, behavior self-monitoring support using Fitbit Charge 2, and weight tracking using a Fitbit Aria Wi-Fi Smart Scale. Changes in weight from baseline to 12 weeks were estimated using a paired 2-tailed t test. Descriptive analyses characterized the use of Fitbit and smart scales. Semistructured interviews were conducted immediately after intervention to assess the participants’ weight loss experiences and perspectives on mHealth technologies.

Results
Of 18 participants, 16 (89%) completed the 12-week assessments; the overall attrition rate was 11.1%. The mean weight loss at week 12 was −4.7 kg (95% CI 7.1 to −2.4 kg; P<.001). Participants wore the Fitbit 71.58% (962/1344) of the intervention days and logged their body weight using the smart scale (410/1344, 30.51% of the intervention days). Participants identified barriers to the use of the technology, such as lack of technological literacy and unreliable internet access for the smart scale.

Conclusions
Although clinically significant weight loss was achieved by integrating mHealth technology into the GCSWLI, adherence to the prescribed use of technology was modest. Addressing barriers to the use of such technologies identified in our work may help to refine an mHealth intervention approach for Hispanic men.

Trial Registration
ClinicalTrials.gov NCT02783521; https://clinicaltrials.gov/ct2/show/NCT02783521
Sustainability of Weight Loss Through Smartphone Apps: Systematic Review and Meta-analysis on Anthropometric, Metabolic, and Dietary Outcomes
Authors: Chew Han Shi Jocelyn , Koh Wee Ling , Ng Janelle Shaina Hui Yi , Tan Ker Kan 
Published: September 2022

Background
Evidence on the long-term effects of weight management smartphone apps on various weight-related outcomes remains scarce.

Objective
In this review, we aimed to examine the effects of smartphone apps on anthropometric, metabolic, and dietary outcomes at various time points.

Methods
Articles published from database inception to March 10, 2022 were searched, from 7 databases (Embase, CINAHL, PubMed, PsycINFO, Cochrane Library, Scopus, and Web of Science) using forward and backward citation tracking. All randomized controlled trials that reported weight change as an outcome in adults with overweight and obesity were included. We performed separate meta-analyses using random effects models for weight, waist circumference, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, blood glucose level, blood pressure, and total energy intake per day. Methodological quality was assessed using the Cochrane Risk of Bias tool.

Results
Based on our meta-analyses, weight loss was sustained between 3 and 12 months, with a peak of 2.18 kg at 3 months that tapered down to 1.63 kg at 12 months. We did not find significant benefits of weight loss on the secondary outcomes examined, except for a slight improvement in systolic blood pressure at 3 months. Most of the included studies covered app-based interventions that comprised of components beyond food logging, such as real-time diet and exercise self-monitoring, personalized and remote progress tracking, timely feedback provision, smart devices that synchronized activity and weight data to smartphones, and libraries of diet and physical activity ideas.

Conclusions
Smartphone weight loss apps are effective in initiating and sustaining weight loss between 3 and 12 months, but their effects are minimal in their current states. Future studies could consider the various aspects of the socioecological model. Conversational and dialectic components that simulate health coaches could be useful to enhance user engagement and outcome effectiveness.

Trial Registration
International Prospective Register of Systematic Reviews (PROSPERO) CRD42022329197; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=329197
DEVELOPMENT AND VALIDATION OF STABILITY INDICATING RP-HPLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF ACLIDINIUM BROMIDE AND FORMOTEROL FUMARATE IN BULK AND INHALER FORMULATION
Authors: LAKSHMI A. JAYA , ABHISHEK K. , PRIYANKA Y. LEELA , BALAJI P. V. , ASHRITHA N. 
Published: September 2022

Objective: To develop a simple, accurate, precise, rapid and sensitive method for the simultaneous estimation of Formoterol fumarate and Aclidinium bromide in pharmaceutical dosage form.
Methods: The chromatogram was run through Ascentis C18 150 x 4.6 mm, 5µ. Mobile phase containing Water: Acetonitrile taken in the ratio 60:40 was pumped through the column at a flow rate of 1.0 ml/min. The temperature was maintained at 30 °C. The optimized wavelength selected was 220 nm.
Results: The retention times of Formoterol fumarate and Aclidinium bromide were found to be 2.953 min and 2.364 min. %RSD of the Aclidinium bromide and Formoterol fumarate was found to be 0.6 and 0.9, respectively. %Recovery was obtained as 99.81 % and 100.20% for Aclidinium bromide and Formoterol fumarate, respectively. LOD, LOQ values obtained from the Signal-to-noise ratio of Aclidinium bromide and Formoterol fumarate were 0.84 µg/ml, 2.56 µg/ml and 0.01 µg/ml, 0.03µg/ml respectively. Regression equation of Formoterol fumarate is y =9023x+268.67, and y = 4661.2x+1941.9 of Aclidinium bromide. Retention times were decreased and that run time was decreased, so the method developed was simple, rapid, sensitive and economical that can be adopted in regular quality control tests in Industries.
Conclusion: Developed and Validated Formoterol fumarate and Aclidinium bromide in pharmaceutical dosage form by using RP-HPLC method.
NEW FTIR METHOD DEVELOPMENT AND VALIDATION FOR QUANTITATIVE ANALYSIS OF FAVIPIRAVIR IN BULK AND PHARMACEUTICAL DOSAGE FORMS
Authors: P. NITHILA , RAGHAVENDRABABU N. , PADMAVATHI Y. , NEENA G. , SUSHMA K. , POOJITHA A. 
Published: September 2022

Objective: A simple spectrophotometric method has been proposed for quantitative analysis of favipiravir in bulk and pharmaceutical dosage form.
Methods: New Fourier transform infrared (FTIR) spectroscopic method has been developed for the estimation of favipiravir by using solid pellet technique.
Results: Results were linear over the 20–100µg/mg concentration range, with correlation values exceeding 0.999. The approach was thoroughly validated in accordance with the recommendations of the International Conference on Harmonization, demonstrating acceptable levels of accuracy, precision, selectivity, robustness, and linearity.
Conclusion: The statistical comparison between this method and HPLC revealed that the newly developed method was significantly distinct. Thus, it proves to be applicable. It met all validation standards over a variety of concentrations and can be used as a substitute for the official procedures.
Pemanfaatan Media Sosial Instagram sebagai Media Promosi untuk Meningkatkan Engagement Pada Kedai Bintoro Kopi
Authors: Novianto  , Y H Suprianto  , R A P Singgih  , Jonathan  , A H Gunadi  , Y P Wibisono  
Published: September 2022

Perkembangan teknologi berkembang sangat pesat dalam beberapa tahun belakangan ini terutama pada media sosial. Salah satu media sosial yang paling banyak digunakan adalah Instagram. Biasanya Instagram digunakan untuk media promosi para pemilik bisnis, baik perusahaan maupun UKM. Salah satu UKM yang menggunakan Instagram sebagai media promosi adalah Kedai Kopi Binkop. Akan tetapi promosi Binkop masih kurang maksimal dari segi desain dan konsistensi. Untuk mengatasi masalah tersebut, diperlukan pelatihan dalam penggunaan media sosial untuk promosi. Pelatihan dilaksanakan sebanyak lima sesi yaitu pelatihan teori desain dan marketing, pelatihan pengaplikasian dan tiga sesi pendampingan. Dari pelatihan ini kedai Kopi Binkop menghasilkan tiga unggahan IG Story dan empat IG Feed. Terlihat dari statistik Insight Instagram Binkop bahwa terdapat kenaikan yang signifikan pada akun yang dijangkau dan akun yang berinteraksi setelah diadakannya pelatihan.
Breast Metastasis of a Completely Regressed Cutaneous Melanoma – Case Report and Review of Literature
Authors: Luana-Andreea Boșoteanu , Mariana Așchie , Tony Hangan , Oana-Andreea Ursică , Mădălina Boșoteanu 
Published: September 2022

Abstract
Spontaneous regression of cutaneous melanoma represents a more frequent circumstance in tumors with intense MelanA immunoprofile. Melanoma-derived breast metastases are uncommon and have been predominantly reported in premenopause, as an indicator for widespread disease. We report the case of a 60-year-old female patient, who presented to the surgical department after auto-palpation of a left mammary mass. Digital mammography indicated malignant characteristics, also objectified in the ipsilateral axillary lymph nodes. The microscopical examination and immunohistochemical profile revealed left nodal and upper-outer mammary quadrant metastases of a BRAF-positive achromic melanoma. The clinical and dermoscopic evaluation confirmed the complete regression of the malignant melanocytic lesion, localised at the level of the right inframammary fold. The upper-outer breast quadrant designates the main site of primary tumors (66%), as well as metastases of other malignancies (50%), due to its well-represented vascularisation and glandular tissue. Dermoscopic characteristics of regressed melanoma comprise scar-like depigmentation and polymorphous vessels (irregular linear and globular). The particularities of this case include the age > 40 years old, survival under therapy with Vemurafenib superior to that cited in the literature (24 months to this date), the involvement of the contralateral lymph nodes in relation to the skin lesion and the inverse diagnostic approach – from pathologist to dermatologist. Completely regressed achromic melanoma, identified through diagnostic techniques performed on clinically apparent loco-regional and distant metastases, represents a rare dermato-oncological entity, with controversial implications regarding the prognosis and survival, that requires future histopathological and dermoscopic homogenization.
Green Synthesis of ZnO Nanoparticles using Piper chaudocanum L. Leaf Extract: Characterization and its Application in Pb (II) Adsorption
Authors: Thao Truong Thi , Tam Khieu Thi , Thom Nguyen Thi Huong , Tuan Nguyen Thuong 
Published: September 2022

In this study, Zinc oxide nanoparticles (ZnO NPs) were green synthesized using Piper chaudocanum L. (PC) leaf extract by sol-gel method and used as an adsorbent for the removal of Pb (II) ions from aqueous solution. The synthesized ZnO NPs were characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), Fourier transform infrared spectroscopy (FTIR), Ultraviolet - visible spectroscopy (UV-Vis) and Brunauer - Emmet - Teller (BET). The results revealed high purity and wurtzite hexagonal structure of ZnO NPs in the size range of 28-37 nm. The morphology of the ZnO NPs varies in different polycrystalline aggregates depending on the amount of extract used, from nanorods to NPs clusters with a BET surface area of 8.56 m2g-1. Pb (II) ion adsorption was investigated at different pH, contact time, initial metal ion concentration, adsorbent dose and temperature. ZnO NPs were synthesized using 30 mL PC leaf extract (ZS30) is the best Pb (II) absorbent. The adsorption isotherm was well described by Langmuir (at low concentration of Pb (II)) and Freundlich isotherm model (at higher concentration of Pb (II)). The adsorption process follows pseudo-second-order reaction kinetic with a high regression coefficient. The calculated thermodynamic parameters, ΔGo (between - 8.699 and - 7.569 kJ/mol at 298 - 316 K), ∆Ho (-20.085 kJ/mol) showed that the adsorption of Pb (II) on ZS30 surface was feasible, spontaneous and exothermic, respectively. The first layer absorption is chemisorption while the next layers are physical adsorption.
ANALISIS HUKUM PIDANA TERHADAP PELANGGARAN KODE ETIK NOTARIS DALAM PEMBUATAN AKTA JUAL BELI SAHAM
Authors: Nugroho Tri Wahyu 
Published: September 2022

Penelitian ini membahasBagaimanakah bentuk pelanggaran Kode Etik yang dilakukan notaris dalam pembuatan akta jual beli saham Bagaimanakah penerapan sanksi terhadap notaris yang melakukan pelanggaran Kode Etik Notaris dalam pembuatan akta jual beli saham?
The Convolutions of the Concept of Age of Consent amongst Primary School Teachers in Zimbabwe
Authors: Pakombwele Agnes , Zvokuomba Kwashirai 
Published: September 2022

The world over the age of consent is used as a child empowerment and protective tool. It has been argued that the age of consent supports teenagers as they negotiate the most profound aspect of childhood transition into adulthood. During this period, children and teenagers face abuse, bodily violence and exploitation. The study sought to analyse the perceptions and views of primary school teachers about age of consent within the educational setting. The study was guided by the interpretivist philosophy and was methodologically underpinned by the qualitative research design, particularly regarding data, which was collected utilising in-depth interviews and focus group discussions to solicit research participants’ opinions, feelings, and thoughts that represent their world views. The study established that teachers had little knowledge about the age of consent due to misrepresentation in the legal frameworks and inconsistencies in the law on the matter. In addition, customary, cultural, and religious practices remain “blind” in the way they approach children’s rights issues. Thus, the article advocates for a child-centred framework when dealing with issues that affect the well-being of children as a way of demystifying the age of consent in the educational sector, which should also be informative not only to teachers but traditional leaders and legal practitioners so as to have a shared understanding of the concept. It is recommended that the age of consent should be the same for both boys and girls just as the age of majority, which is at 18 years.
A Case for a Relational Approach in Development Interventions: Measuring the Relationships of an NGO in South Africa
Authors: Holtzhausen Marlie , Musyoka Jason 
Published: September 2022

This article argues in favour of relationships as a measure of development. The study gathered primary data from the James 1:27 Trust, a non-governmental organisation providing socio-economic and psychological support to vulnerable households in Pretoria, South Africa. The data were gathered through a qualitative method by which three officials from the James 1:27 Trust and seven participants from three households targeted by the James 1:27 Trust were interviewed. The in-depth interviews were complemented by a focus group discussion, which combined the Trust officials and the households. A thematic content analysis was used to interpret and analyse the data. The study concluded that the nature and extent of relationships in the examined non-governmental organisation present an opportunity to understand and measure development differently from the way it is understood and measured in orthodox development. The participants used burdened words such as family, belonging, appreciation, value, bonding, paying attention, and honesty as proxies for measuring development. These findings provide insight into the meaning of relationships in development processes and outcomes. The article recommends that care relationships be moved from the shadows to the mainstream of development practice.
Swiss Biotech Day, May 2022. Sustainability Across the Pharmaceutical Value Chain - How Switzerland Could Take a Leading Role in Promoting a Greener Approach
Authors: Gehring Marta , Meyer Hans-Peter 
Published: September 2022

The sustainability of the pharmaceutical industry has aroused interest from various sectors and disciplines, including chemistry, biology and engineering. Given the Swiss drug sector’s innovative engine and enormous economic importance, a Swiss Biotech Day panel discussion was held in May 2022 in Basel to address the question of how “sustainability across the pharmaceutical value chain” can be edged forward in Switzerland. Roche, Lonza, Pheida, ETH, the Swiss Academy of Engineering Sciences (SATW), and a newly established collaborative, Circular Carbon for Chemistry (ccLoop) joined forces and agreed that sustainability must become a key strategic goal for the industry in Switzerland. The panel looked at the sustainability challenge, at how a green transition can be achieved faster, and at how industrial biotechnology applications can improve industry’s performance, energy efficiency and product value while yielding viable sustainable solutions to protect our environment. Switzerland is a leader in drug development and manufacturing. By placing greater energy and resources on the sustainability equation, we ensure continued leadership and a greener world. ‘Swissness’ will increasingly have to denote effective drugs produced sustainably.
KECENDERUNGAN BODY DYSMORPHIC DISORDER DENGAN KEPERCAYAAN DIRI PADA MAHASISWI
Authors: Prakoso Ihsan Budi , Budiyani Kondang , Rinaldi Martaria Rizky 
Published: September 2022

Abstrak Saat ini mahasiswa sering mengeluhkan tentang kepercayaan diri yang rendah, padaha dengan rasa percaya diri yang rendah mahasiswa akan kesulitan dalam menyesuaikan diri terhadap lingkungan yang baru, tidak mempunyai pegangan hidup yang kuat dan kurang mampu mengembangkan motivasinya. Penelitian ini bertujuan untuk mengetahui hubungan antara kecenderungan body dysmorphic disorder dengan kepercayaan diri pada mahasiswi Universitas Mercu Buana Yogyakarta. Hipotesis dalam penelitian ini adalah ada hubungan negative antara kecenderungan body dysmorphic disorder dengan kepercayaan diri pada mahasiswi Universitas Mercu Buana Yogyakarta. Subjek dalam penelitian ini yaitu 107 mahasiswi Universitas Mercu Buana Yogyakarta. Pengumpulan data menggunakan skala kecenderungan body dysmorphic disorder dan skala kepercayaan diri. Data kemudian dianalisis menggunakan analisis korelasi product moment. Berdasarkan hasil analisis diperoleh koefisien korelasi (rxy) = -0,475dengan taraf signifikansi p = 0,000 (p<0,01). Hal ini menunjukkan bahwa hipotesis dalam penelitian ini diterima dan terbukti bahwa ada hubungan negative kecenderungan body dysmorphic disorder dengan kepercayaan diri pada mahasiswi Universitas Mercu Buana Yogyakarta. Koefisien determinasi (R2) = 0,225 maka sumbangan efektif kecenderungan body dysmorphic disorder dalam kepercayaan diri adalah sebesar 22,5% dan sisanya 77,5% diperoleh dari factor lain. Kata Kunci: Kecenderungan Body Dysmorphic Disorder, KepercayaanDiri Abstract Nowadays students often complain about low self-confidence, with low self-esteem, students will have difficulty adjusting to a new environment, do not have a strong grip on life and are less able to develop their motivation. This research aims to find out the relationship between tendency of body dysmorphic disorder with self confident among female students of MercuBuana Yogyakarta University. This research hypothesizes that there is a negative relationship between tendency of body dysmorphic disorder with self confident among female students of MercuBuana Yogyakarta University. Subjects in this study were 107 of female students of MercuBuana Yogyakarta University. The data of this study were collected using the Tendency of Body Dysmorphic Disorder Scale and the Self Confident Scale. The data analysis method was used product-moment correlation. Based on the analysis, the coefficient correlation (rxy) = -0,475 with the significant level = 0,000 (p<0,010), which means that there is a negative relationship between tendency of body dysmorphic disorder with self confident among female students of MercuBuana Yogyakarta University. The coefficient determination (R2) = 0.225, so tendency of body dysmorphic disordercontributes effectively 22,5% to self confidentwhile the remaining 77,5% is derived from other factors. Keywords: Tendency of Body Dysmorphic Disorder, Self Confidence
MOTIVASI BERPRESTASI DAN KETANGGUHAN MENTAL ATLET
Authors: Sholicha Ima Fitri , W Awidha Dwi 
Published: September 2022

Abstrak Penelitian ini berujuan untuk mengetahui hubungan antara motivasi berprestasi dengan ketangguhan mental atlet. Subjek penelitian ini adalah atlet Tae-Kwon-Do. Instrumen yang digunakan yaitu Skala Motivasi Berprestasi dan Skala Ketangguhan Mental. Analisis yang akan digunakan yaitu analisis korelasi. Hasil analisis uji product moment diperoleh nilai p = 0.831, (p>0.05) maka dapat disimpulkan bahwa tidak terdapat hubungan antara motivasi berprestasi dengan ketangguhan mental. Ketidakadanya hubungan antara motivasi berprestasi dengan ketangguhan mental dimungkinkan adanya variabel intervening diantara kedua variabel tersebut, seperti komunikasi interpersonal, self efficacy dan proses latihan. Kata Kunci: Motivasi Berprestasi, Ketangguahan Mental dan Atlet Abstract This study aims to see the relationship between achievement motivation and mental toughness of athletes. The subjects of this study were Tae-Kwon-Do athletes. The instruments used were Achievement Motivation Scale and Mental Toughness Scale. The analysis used is correlation analysis. The result of the product moment test showed that the value of p = 0.831, (p> 0.05), it can be concluded that there is no relationship between achievement motivation and mental toughness. The absence of a relationship between achievement motivation and mental toughness, it is possible that there are variables that connect the two variables, such as interpersonal communication, selfefficacy and the training process. Keywords: Achievement Motivation, Mental Toughness and Athletes
Komitmen Organisasi Terhadap Disiplin Kerja Pada Tenaga Keperawatan
Authors: Nur F. A. S Eka Wahyu , Rejeki Asri , Endah Puspitaningrum Noer Suci 
Published: September 2022

Abstrak
Penelitian ini bertujuan untuk mengetahui apakah ada pengaruh Komitmen Organisasi terhadap Disiplin Kerja pada Tenaga Keperawatan di Rumah Sakit X. Penelitian ini menggunakan pendekatan kuantitatif. Teknik sampel yang digunakan yaitu teknik sampling incidental. Metode pengumpulan data yang digunakan oleh kedua variabel adalah kuesioner yang disusun dalam bentuk skala likert dengan rentang skala antara 1-4. Analisis data yang digunakan dalam penelitian ini menggunakan teknik regresi linear sederhana dengan software SPSS 25.0 for windows. Hasil penelitian ini menunjukkan bahwa nilai R Square sebesar 0.477 yang menunjukkan bahwa adanya pengaruh variabel komitmen organisasi sebesar 47.7%, sedangkan sisanya 52.3% dipengaruhi oleh variabel lain yang tidak diteliti, sehingga hipotesis dalam penelitian ini adalah Ha diterima dan H0 ditolak. Berdasarkan analisis data tersebut, maka dapat disimpulkan bahwa terdapat pengaruh komitmen organisasi terhadap disiplin kerja pada tenaga keperawatan di rumah sakit X.