bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determination of Enzymatic Antioxidant in Iraqi Patients with Chronic Gastritis
Authors: A. Bakir Wasan , M. Hussein Shalal , A. Mahmood Noah 
Published: March 2022

Infection of the gastric mucosa with Helicobacter pylori is strongly associated with chronic gastritis, peptic ulcer and gastric cancer. Helicobacter pylori virulence factors include a variety of proteins that are involved in its pathogenesis, such as VacA and CagA. Another group of virulence factors is clearly important for colonization of H.pylori in the gastric mucosa. These include urease, motility factors (flagellin), and Superoxide dismutase (SOD). Because of this organism's microaerophilic nature and the increased levels of reactive oxygen in the infected host, we expect that other factors involved in the response to oxidative stress are likely to be required for virulence. Superoxide dismutase is a nearly ubiquitous enzyme among organisms that are exposed to toxic environments. In this study, we measured the SOD in serum of 80 patients complain from chronic gastritis and infected with H.pylori. 37 patients infected with H.pylori have the CagA gene, and 13 patients are not and also measured the SOD in 30 control groups that not infected with H.pylori. Serum level of SOD was significantly (p<0.05) higher in patients with chronic gastritis compared to controls. Also significantly higher (p<0.001) in patients with chronic gastritis infected with H.pylori positive CagA than patients infected with H.pylori negative CagA.
Key words: chronic gastritis, H.pylori, CagA, SOD
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Spectroscopic Study for Determination of Amoxicillin Using Cobalt(II) as Complexing Metal
Authors: M.J. Al-Mudhafar May 
Published: March 2022

This study includes analytical methods for the determination of the drug amoxicillin trihydrate (Amox.) in some pharmaceutical preparations using Cobalt ion (Co(II)) as complexing metal. The best conditions for complexation were: the reaction time was 20 minutes, pH=1.5 and the best temperature of reaction was 70 ËšC. Benzyl alcohol was the best solvent for extraction the complex.
Keywords: Amoxicillin, Cobalt(II), Complex, Molar ratio.
Outcome following surgery for insulo-opercular epilepsies
Authors: Jayapaul Pushkaran , Gopinath Siby , Pillai Ashok 
Published: March 2022

OBJECTIVE
The purpose of this study was to evaluate the clinical outcome in patients with medically refractory epilepsy who had undergone resective or ablative surgery for suspected insulo-opercular epileptogenic foci.

METHODS
The prospectively maintained database of patients undergoing epilepsy surgery was reviewed, and all patients who underwent insulo-opercular surgery for medically refractory epilepsy with a minimum of 12 months of postoperative follow-up were identified, excluding those who had insulo-opercular resection in combination with temporal lobectomy. The presurgical electroclinicoradiological data, stereo-EEG (SEEG) findings, resection/ablation patterns, surgical pathology, postoperative seizure outcome, and neurological complications were analyzed.

RESULTS
Of 407 patients undergoing epilepsy surgery in a 5-year period at the Amrita Advanced Centre for Epilepsy, 24 patients (5.9%) who underwent exclusive insulo-opercular interventions were included in the study. Eleven (46%) underwent surgery on the right side, 12 (50%) on the left side, and the operation was bilateral in 1 (4%). The mean age at surgery was 24.5 ± 12.75 years. Onset of seizures occurred on average at 10.6 ± 9.7 years of life. Characteristic auras were identified in 66% and predominant seizure type was hypermotor (15.4%), automotor (15.4%), hypomotor (11.5%), or a mixed pattern. Seventy-five percent of the seizures recorded on scalp video-EEG occurred during sleep. The 3T MRI results were normal in 12 patients (50%). Direct single-stage surgery was undertaken in 5 patients, and SEEG followed by intervention in 19. Eighteen patients (75%) underwent exclusive resective surgery, 4 (16.7%) underwent exclusive volumetric radiofrequency ablation, and 2 (8.3%) underwent staged radiofrequency ablation and resective surgery. Immediate postoperative neurological deficits occurred in 10/24 (42%), which persisted beyond 12 postoperative months in 3 (12.5%). With a mean follow-up of 25.9 ± 14.6 months, 18 patients (75%) had Engel class I outcome, 3 (12.5%) had Engel class II, and 3 (12.5%) had Engel class III or IV. There was no statistically significant difference in outcomes between MRI-positive versus MRI-negative cases.

CONCLUSIONS
Surgery for medically refractory epilepsy in insulo-opercular foci is less common and remains a challenge to epilepsy surgery centers. Localization is aided significantly by a careful study of auras and semiology followed by EEG and imaging. The requirement for SEEG is generally high. Satisfactory rates of seizure freedom were achievable independent of the MRI lesional/nonlesional status. Morbidity is higher for insulo-opercular epilepsy surgery compared to other focal epilepsies; hence, the practice and development of minimally invasive strategies for this subgroup of patients undergoing epilepsy surgery is perhaps most important.
Effect of comorbid Parkinson’s disease and Parkinson’s disease dementia on the course of idiopathic normal pressure hydrocephalus
Authors: Sakurai Anri , Tsunemi Taiji , Shimada Tomoyo , Kawamura Kaito , Nakajima Madoka , Miyajima Masakazu , Hattori Nobutaka 
Published: March 2022

OBJECTIVE
The objective of this study was to analyze the effect of concomitant Parkinson’s disease (PD) and PD dementia (PD/PDD) on the course of idiopathic normal pressure hydrocephalus (iNPH), especially as related to the outcome of lumboperitoneal shunt (LPS) surgery.

METHODS
The authors retrospectively analyzed patients with iNPH without accompanying disorders (iNPH alone [iNPHa]) and iNPH concomitant with PD/PDD (iNPHc+PD/PDD) who had presented to their department between 2010 and 2019. The diagnosis of iNPHc+PD/PDD was established using the diagnostic criteria of the Movement Disorder Society. The effect of LPS surgery on clinical symptoms and striatum volumes was evaluated.

RESULTS
Thirty-three patients with iNPHa and 23 patients with iNPHc+PD/PDD were identified. Comorbid PD/PDD significantly worsened clinical outcome as measured by the iNPH grading scale, modified Rankin Scale (mRS), and Hoehn and Yahr (HY) scale. LPS surgery improved the iNPH score including gait disturbance (p < 0.01), cognitive impairment (p = 0.02), and urinary disturbance (p < 0.01) in iNPHa and improved gait disturbance (p = 0.01) and urinary disturbance (p = 0.03) in iNPHc+PD/PDD for 1 year. Comorbid synucleinopathies maintained worse mRS scores and HY stages for 3 years, and LPS surgery extended overall survival (p = 0.003), as well as the period of sustained mRS scores (p = 0.04) and HY stages (p = 0.004) in iNPHc+PD/PDD. Both caudate and putamen volumes were reduced in iNPHa (p < 0.01) compared to those in controls and in patients with iNPHc+PD/PDD compared to those in patients with PD/PDD (p < 0.01), and LPS surgery restored caudate volumes in both groups.

CONCLUSIONS
These results revealed that comorbid PD/PDD deteriorates the clinical course of iNPH and that LPS surgery is recommended regardless of this comorbidity.
Safety and effectiveness of the assessment and treatment of idiopathic normal pressure hydrocephalus in the Adult Hydrocephalus Clinical Research Network
Authors: Williams Michael A. , Nagel Sean J. , Golomb James , Jensen Hailey , Dasher Nickolas A. , Holubkov Richard , Edwards Richard J. , Luciano Mark G. , Zwimpfer Thomas J. , Katzen Heather , Moghekar Abhay , Wisoff Jeffrey H. , McKhann Guy M. , Hamilton Mark G. 
Published: March 2022

OBJECTIVE
The aim of this study was to describe the processes and outcomes associated with patients at five sites in the Adult Hydrocephalus Clinical Research Network (AHCRN) who had undergone evaluation and treatment for suspected idiopathic normal pressure hydrocephalus (iNPH) and had 1-year postoperative follow-up.

METHODS
Subjects with possible iNPH who had been prospectively enrolled in the AHCRN registry between November 19, 2014, and December 31, 2018, were evaluated by CSF drainage via either lumbar puncture or external lumbar drainage, consistent with recommendations of the international iNPH guidelines. Standardized clinical evaluations of gait, cognition, urinary symptoms, depression, and functional outcomes were conducted at baseline, before and after CSF drainage, and at 4-month intervals after shunt surgery. Complications of CSF drainage and shunt surgery were recorded.

RESULTS
Seventy-four percent (424/570) of patients with possible iNPH had CSF drainage, and 46% of them (193/424) underwent shunt surgery. The mean change in gait velocity with CSF drainage was 0.18 m/sec in patients who underwent shunt surgery versus 0.08 m/sec in patients who did not. For shunt surgery patients, gait velocity increased by 54% from 0.67 m/sec before CSF drainage to 0.96 m/sec 8–12 months after surgery, and 80% of patients had an increase of at least 0.1 m/sec by the first postoperative visit. Evaluation of cognition, urinary symptoms, depression, and functional outcomes also revealed improvement after shunt surgery. Of 193 patients who had undergone shunt surgery, 176 (91%) had no complications and 17 (9%) had 28 complications. Eleven patients (6%) had 14 serious complications that resulted in the need for surgery or an extended hospital stay. The 30-day reoperation rate was 3%.

CONCLUSIONS
Using criteria recommended by the international iNPH guidelines, the authors found that evaluation and treatment of iNPH are safe and effective. Testing with CSF drainage and treatment with shunt surgery are associated with a high rate of sustained improvement and a low rate of complications for iNPH in the 1st year after shunt surgery. Patients who had undergone shunt surgery for iNPH experienced improvement in gait, cognitive function, bladder symptoms, depression, and functional outcome measures. Gait velocity, which is an easily measured, objective, continuous variable, should be used as a standard outcome measure to test a patient’s response to CSF drainage and shunt surgery in iNPH.
Handlungsempfehlungen zur Verbesserung von Effektivität und Effizienz der Planung und Steuerung von Bauprojekten in einem Mittelständischen Generalplanungsunternehmen
Authors: Rudnik Angelika , Siegfried Patrick 
Published: March 2022

Bauprojekte sind in der Regel komplexe Vorhaben. Sie werden mit Hilfe des Projektmanagements und dessen Verfahren, Prozessen und Techni-ken bewältigt. Dennoch sind deutsche Bauprojekte nicht selten von Kos-ten- und Terminüberschreitungen betroffen.
Ziel dieser Arbeit ist es, mögliche Optimierungsfelder im Planungs- und Steuerungsprozess eines Unternehmens für Industriebauprojekte zu iden-tifizieren und darauf aufbauende Verbesserungsansätze zu erarbeiten. Um die Ziele verfolgen zu können, wurde eine qualitative Sozialforschung mittels Experteninterviews durchgeführt. Die Expertenaussagen verdeutli-chen weiterhin Optimierungspotenzial, sowohl im Planungs- als auch im Steuerungsprozess. Ausgewählte Techniken (hauptsächlich aus dem klas-sischen Projektmanagement) dienen indessen dazu, die Effektivität und Effizienz des Planungsprozesses zu erhöhen. Innerhalb des Steuerungs-prozesses zeigt sich, dass viele Optimierungsbereiche der Steuerung auf den Defiziten der Planung beruhen
Mechanized processing of building equipment by abrasive working bodies
Authors: Abrashkevich Yury , Machyshyn Hrigoriy , Marchenko Oleksandr , Komotska Svitlana 
Published: March 2022

Carrying out of the clearing operations at carrying out mechanized processing of construction equipment from paints and varnishes, rust, various kinds of pollution belongs to mass labour-consuming operations [1]. To carry out these operations, widespread use of hand-held machines, working bodies that have abrasive wheels and metal brushes. The versatility and versatility of these machines, combined with the correct selection of the desired abrasive work tool, can significantly accelerate and facilitate the performance of cleaning and grinding operations with the desired effect.
However, most of them have drawbacks in the cleaning of thin-sheet metal, since the removal of the base metal also takes place, which in most cases is not acceptable. So when processing non-metallic materials with metal brushes the working surface is clogged with small particles of metal, which subsequently leads to the formation of rust, and when cleaning the metal surfaces grooves are formed. Metal brushes are also ineffective in cleaning surfaces of synthetic enamels, curvilinear surfaces and inaccessible areas. Machining these tools is energy-intensive and requires the use of heavy-duty hand machines. Fiber and petal abrasive tools are not self-cleaning and lose their cutting power due to the filling of the intergranular space with cleaning waste. Sand blasting is environmentally hazardous for workers and the environment, since the sand consumables fly over long enough distances (especially when clearing tall structures and structures).
The analysis showed that one of the effective tools for cleaning metal and non-metal surfaces from paint coatings, rust and other contaminants without removing the base material layer is a polymer-abrasive brush. However, there is insufficient research on the mechanism of its operation, energy and thermal processes that occur during operation and have a decisive influence on the performance of the polymer-abrasive brush.
The results of studies of the influence of structural and mode parameters of manual angle grinders with polymer-abrasive brushes are presented in the paper. The study of these issues is an urgent task, as it will allow to determine the parameters of the drive machine, rational modes and schemes of their operation, as well as the scope of use of such working bodies.
Calculations difference of hight-speed working units depending on the kinematics of their working processes
Authors: Teteriatnyk Oleksandr , Rashkivskiy Volodymyr 
Published: March 2022

High-speed working units are very widely used in modern construction, in the destruction of durable materials and soils and more. When calculating the power and energy parameters of dynamic working units take into account changes in the nature of the interaction of the cutting element with the environment and the emergence and propagation of soil stresses from the action on the boundary of the array of the cutting element. This leads to the emergence of a stress-strain state in the soil mass, which has an oscillatory-wave character.
The nature of the stress-strain state is influenced by the state of the working environment and the speed of cutting (destruction) of the soil mass.
An unsolved problem in the dynamic destruction of soils is to take into account the kinematic features and technology of work with high-speed peripheral and front-end working units. The design parameters of these working units must take into account not only the dynamic parameters of the fracture process, but also the phenomenon of accumulation of fatigue deformations in the working environment.
Tracing the Theory of Hadith Quality in Kitab al-Jami' al-Sahih al-Sunan al-Tirmidzi
Authors: Ach Baiquni Baiquni 
Published: March 2022

This paper tries to describe some of imam al-Tirmidizi's views related to the theory of hadith quality found in the book al-Jami al-Şahih al-Sunan al-Tirmîdzi , this paper is a literature study with a descriptive approach that yields the conclusion that Imam al-Tirmîdzi has a different concept than the hadith expert in describing the hadith ṣahīh, hasan and dha’īf. In the case of ṣahīh hadith, the theory used by imam al-Tirmdizi is almost the same as other hadith experts i.e. hadith sahih is a hadith whose isith continues, Narrated by the 'adil and dhabīt, while in the theory of hasan hadith, Tirmidzi has a unique concept that divides hasan into three namely hasan ṣahīh (hadith hasan approaching ṣahīh), hasan (hadith that exists about hasan sahih and gharīb) and hasan gharīb is a hadith that is close to hadith dha’īf. Then, the theory of dha’īf by Imam al-Tirmîdzi is the same as other hadith scholars who do not meet ṣahīh and hasan and the connection of sanad is questioned.
Upaya Pemerintahan Desa Dan Kelompok Perlindungan Anak Desa Faennake Dalam Memberikan Perlindungan TerhadapAnak Dari Tindakan Kekerasam
Authors: Kolne Yakobus , Suni Melkianus , Anggraini Tri 
Published: March 2022

Setiap anak memiliki haknya sesuai dengan harkat dan martabat kemanusiaan, serta mendapat perlindungan dari kekerasan dan diskriminasi sesuai dengan Undang – Undang Nomor 35 Tahun 2014 tentang Perlindungan Anak. Upaya Perlindungan Anak yang dilakukan oleh Pemerintahan Desa dan Kelompok Perlindungan Anak Desa Faennake merupakan Upaya Kemitraan atau Koordinasi dalam melaksanakan kegiatan – kegiatan Perlindungan Anak sehingga hak–hak anak di Desa Faennake dapat terpenuhi. Penelitian ini bertujuan untuk mendeskripsikan Upaya Pemerintahan Desa dan Kelompok Perlindungan Anak Desa Faennake dalam memberikan perlindungan anak dari tindak kekerasan serta faktor–faktor pendukung dan penghambat kegiatan perlindungan terhadap anak dari tindak kekerasan. Metode Penelitian yaitu deskriptif kualitatif dengan teknik pengumpulan data berupa observasi, wawancara dan dokumentasi. Dari hasil penelitian menunjukkan bahwa koordinasi, komunikasi dan konsultasi lintas sektor yang memprioritaskan hak–hak anak dalam perencanaan di desa sudah terlaksana namun belum maksimal karena dalam perencanaan program perlindungan anak belum menjadi prioritas terbukti dengan Belum tersedianya Perda dan Perdes Pelindungan Anak yang diakibatkan oleh rendahnya sumber daya yang dimiliki dan sosialisasi terhadap aturan-aturan yang mengatur tentang perlindungan dan hak-hak anak belum dilakukan secara baik. Peneliti menyarankan bahwa perlu adanya koordinasi yang baik antar stakeholer demi terwujudnya anak-anak yang bebas dari tindak kekerasan.
INSTITUSIONALISASI DEMOKRASI KONSENSUS DALAM PEMILIHAN KEPALA DESA DI DESA TUN’NOE, KECAMATAN MIOMAFFO TIMUR, KABUPATEN TIMOR TENGAH UTARA
Authors: Usboko Ignasius 
Published: March 2022

Pemilihan kepala desa merupakan wujud kedaulatan rakyat dalam aras lokal menyangkut pemosisian penting rakyat dan penentuan pemimpin yang patut dikelola sebagai antisipasi potensi konflik. Penelitian dilakukan untuk mengetahui institusionalisasi dan makna demokrasi konsensus bagi desa. dengan cara deskriptif kualitatif dengan teknik wawancara dan dokumentasi, teknik analisis model interaktif. Hasil penelitian menunjukkan: 1) adanya model pelembagaan, (a) derajat kesisteman (b) derajat identitas nilai (c) derajat otonomi (d) derajat pengetahuan; 2) terdapat budaya kesepakatan terhadap calon kepala desa dari suku-suku yang ada di Desa Tun’noe yaitu Suku Nabu, Suku Ukat, Suku Nino Tulak dengan Suku Ulan dan Suku Kefi Subai sebagai suku saudara perempuan dan Suku Nino Saluat, setiap suku memiliki kesempatan untuk menjadi calon secara estafet. Namun ada pertimbangan terhadap calon muda yang diganti dengan calon kalangan tua karena calon muda dianggap belum mampu memimpin. 3). budaya konsensus dimaknai sebagai instrumen penentuan pemimpin secara periodik yang damai dan distribusi perangkat desa yang adil. Rekomendasi: secara kontekstual, perlunya konsistensi dalam penerapan peraturan perundang-undangan, dan secara kultural, perlunya pemeliharaan secara adat melibatkan kalangan tua dan muda agar demokrasi konsensus berjalan efektif dan beradaptasi dengan perkembangan masyarakat.
Kata Kunci: Pemilihan Kepala Desa, Institusionalisasi dan Demokrasi Konsensus
TUNTUTAN MASYARAKAT TERHADAP PEMEKARAN DESA DI DESA WEOE KECAMATAN WEWIKU KABUPATEN MALAKA
Authors: Hoar Engelbertha Rosina , Mael Medan Yonathan , Festianto Dian 
Published: March 2022

Masalah yang diangkat dalam penelitian ini adalah Tuntutan Masyarakat Terhadap Pemekaran Desa, sudah sejauh mana tuntutan itu di tindak lanjut. Tujuan penelitian ini, untuk mengetahui tuntutan masyarakat terhadap pemekaran desa di desa Weoe dan proses penghambat tuntutan masyarakat terhadap pemekaran desa belum terlaksana atau tereaslisasi. Metode yang diangkat dalam penelitian ini adalah deskritif kualitatif yaitu menggambarkan dan menjelaskan serta menguraikan data – data yang diperoleh dari hasil penelitian pada lokasi penelitian dengan teknik pengumpulan data melalui hasil wawancara. Hasil penelitian menunjukkan bahwa, pelayanan pemerintah desa kepada masyarakat tidak merata, sehingga menimbulkan rasa ketidak adilan dan rasa ketidak puasan masyarakat atas kinerja aparatur pemerintah desa, sehingga timbulah keinginan masyarakat untuk menuntut agar proses pemekaran desa dapat terlaksana. Jadi peneliti menyimpulkan bahwa masyarakat Weoe mengharapkan atau berkeinginan untuk menghadirkan sebuah desa baru melalui pemekaran desa yang mana, dapat dilihat dari kinerja aparatur desa atas pelayanan yang tidak merata, jumlah penduduk dan luas wilayah tersebut sudah layak untuk dimekarkan menjadi sebuah desa baru. Selain itu, pemerintah desa perlu meningkatkan kapasitas sumber daya manusia terutama aparatur pemerintah desa, dan pemekaran desa Weoe pada dasarnya untuk meningkatkan rasa keadilan dan menciptakan kesejahteraan bagi masyarakat.
KINERJA APARAT DALAM MEMBERIKAN PELAYANAN DI KANTOR CAMAT SANTIAN KABUPATEN TIMOR TENGAH SELATAN
Authors: Tano Bonifasius 
Published: March 2022

Masalah yang dilihat dalam penelitian ini adalah Faktor-faktor apa saja yang mempengaruhi kinerja aparat dalam memberikan pelayanan di Kantor Camat Santian Kabupaten Timor Tengah Selatan.Metode yang digunakan dalam penelitian ini adalah deskriptif kualitatif.Dengan sumber data yakni data primer dan data sekunder. Berdasarkan hasil penelitian tersebut maka peneliti memberikan kesimpulan bahwa: Faktor yang mempengaruhi pemberian pelayanan aparat di Kantor Camat Santian Kabupaten Timor Tengah Selatan terkait dengan kualitas sumber daya manusia, sarana dan prasarana, anggaran atau dana dan peralatan yang di gunakan di Kecamatan Santian, masih sangat minim sehingga mempengaruhi pelayanan kepada masyarakat. Sementara indicator lain seperti pelayanan tepat waktu dan prosedur pelayan di Kecamatan Santian juga masih belum sesuai dengan prosedurnya, terkadang ada keterlambatan pelayanan terhadap masyarakat umumnya. Faktor-faktor tersebut di atas, semuanya di pengaruhi karena kurangnya sarana dan prasarana di Kantor Camat Santian Kabupaten Timor Tengah Selatan. Untuk itu peneliti memberikan saran kepada pemerintah Kecamatan Santian diharapkan untuk dalam melaksanakan pelayanan kepada masyarakat perlu memperbanyak sarana dan prasarana di kantor Camat Santian kuhususnya sarana dan prasarana yang berkaitan dengan pelayanan kepada masyarakat, sementara indicator anggaran atau dana,diharapkan kepada aparat Kecamatan Santian agar tidak lagi melakukan pungutan kepada masyarakat namun perlu meningkatkan pengelolaan terhadap anggaran atau dana pemerintah.