bluuebunny/crossref_metadata_2025_split huggingface dataset:
Arbitrarily Accurate Analytical Approximations for the Error Function
Authors: Howard Roy M. 
Published: February 2022

A spline-based integral approximation is utilized to define a sequence of approximations to the error function that converge at a significantly faster manner than the default Taylor series. The real case is considered and the approximations can be improved by utilizing the approximation erf(x)≈1 for |x|>xo and with xo optimally chosen. Two generalizations are possible; the first is based on demarcating the integration interval into m equally spaced subintervals. The second, is based on utilizing a larger fixed subinterval, with a known integral, and a smaller subinterval whose integral is to be approximated. Both generalizations lead to significantly improved accuracy. Furthermore, the initial approximations, and those arising from the first generalization, can be utilized as inputs to a custom dynamic system to establish approximations with better convergence properties. Indicative results include those of a fourth-order approximation, based on four subintervals, which leads to a relative error bound of 1.43 × 10−7 over the interval [0, ∞]. The corresponding sixteenth-order approximation achieves a relative error bound of 2.01 × 10−19. Various approximations that achieve the set relative error bounds of 10−4, 10−6, 10−10, and 10−16, over [0, ∞], are specified. Applications include, first, the definition of functions that are upper and lower bounds, of arbitrary accuracy, for the error function. Second, new series for the error function. Third, new sequences of approximations for exp(−x2) that have significantly higher convergence properties than a Taylor series approximation. Fourth, the definition of a complementary demarcation function eC(x) that satisfies the constraint eC2(x)+erf2(x)=1. Fifth, arbitrarily accurate approximations for the power and harmonic distortion for a sinusoidal signal subject to an error function nonlinearity. Sixth, approximate expressions for the linear filtering of a step signal that is modeled by the error function.
Una cuestión por aclarar: mujeres, escritura, academia
Authors: Suárez Ortiz Giovana 
Published: February 2022

El año pasado, al terminar de leer Caliban y la bruja. Mujeres, cuerpo y acumulación originaria de Silvia Federici, lloré por todas las feminidades que han sido y que seguimos siendo quemadas en las hogueras de la historia, en las frases cotidianas y en las violencias de género. Esa noche no lograba conciliar el sueño, sentía un calor intenso en las piernas. No sabía qué me estaba pasando. A la mañana siguiente busqué entre mi archivo un texto de Suely Rolnik que habla acerca de los saberes-del-cuerpo. Ella me ayudó a entender las razones de mi desvelo, mi cuerpa me estaba hablando, me estaba recordando que nuestras cuerpas se definen por la capacidad de afectar y ser afectados y que, al definirnos como cuerpas mujeriles, nos han subordinado.
Los abuelos favoritos desde la percepción de preadolescentes de la ciudad de Armenia
Authors: Ruiz-Soto María Claudia , Pineda-Chacón Olga Mercedes , Valencia-Restrepo Sandra Milena 
Published: February 2022

Esta investigación forma parte de los estudios sobre Abuelidad, que adelanta el Grupo de Investigación sobre Desarrollo de la Universidad del Quindío. Se describe, desde la percepción de preadolescentes de la ciudad de Armenia, la figura del abuelo favorito a partir de características del abuelo (edad, sexo, familia de origen, ocupación, ubicación geográfica y frecuencia de contacto) y como ésta varía en función de las características del nieto.
La muestra estuvo conformada por 600 preadolescentes de distintas instituciones educativas a los cuales se les aplicó un instrumento sobre la relación abuelo-nieto. Los datos fueron procesados en Stadistical Product and Service Solutions (SPSS), se utilizó estadística descriptiva, en la identificación de la figura del abuelo favorito y para establecer diferencias significativas en función las características del nieto, el Chi-cuadrado y la prueba U de Mann Whitney.
Los resultados indican que los nietos eligen como abuelo favorito en mayor porcentaje a abuelas (81.4%), de línea materna (62.1%), entre 60 y 70 años (43.8%), jubilados o amas de casa (72.8%), viven en la misma ciudad que sus nietos (32.7%), les ven casi todos los días (47.4%). Se encontró que las características de la figura del abuelo presenta variaciones en función de características del preadolescente. Así, la edad del abuelo favorito varía de acuerdo con la estructura familiar y el orden de nacimiento del nieto, cuando la madre trabaja, los nietos prefieren en mayor proporción a las abuelas maternas; la distancia geográfica y la frecuencia de contacto entre abuelos favoritos y nietos varían en función de la estructura familiar, el número de hermanos y el orden de nacimiento del preadolescente
Estructura y composición de la comunidad de orquídeas en dos zonas de la Reserva Natural “La Montaña del Ocaso” Quimbaya-Quindío
Authors: Santa-Jiménez Nhora Nitzanim , García-Rodríguez Tatyana , Gómez-Marín Germán Darío 
Published: February 2022

Se realizó un estudio comparativo en la zona de guadual mixto y selva secundaria de la reserva natural “La Montaña del Ocaso”, evaluando la estructura y composición de la comunidad de orquídeas en relación con la vegetación asociada, dando como resultado el registro de 18 especies de orquídeas distribuidas en 14 géneros, haciendo 3 reportes nuevos para la reserva: Ponera striata, Pelexia laxa y Jacquiniella teretifolia. En el guadual mixto se registraron 10 especies de orquídeas exclusivas de la zona y en la selva secundaria 3 y 5 especies se compartieron en las dos zonas. En cuanto a la vegetación asociada a la comunidad de orquídeas, se registraron 41 especies, organizadas en 21 familias botánicas; en la selva secundaria se encontraron 20 especies y en la zona de guadual mixto 5 y comparten 16 especies en las dos zonas. Del total registrado 9 son hospederos de orquídeas, donde S. longicaulis (la especie más dominante) se distribuyó en 7 de los 9. Se hicieron análisis de componentes para observar la distribución y la preferencia de sustratos por las orquídeas, registrándose en los 13 m mayor número de especies de orquídeas que los otros rangos de altura y el sustrato más frecuentado por las orquídeas fue el liquen. Se evaluaron en el programa ANOVA los índices de Shannon, Simpson, equitabilidad y riqueza para las dos zonas, dando como resultado que la diversidad es baja tanto para la zona de selva secundaria como para el guadual mixto, se presentó dominancia en las dos zonas de acuerdo al índice de Simpson; sin embargo, se presentaron diferencias significativas entre las zonas en cuanto a estos índices, mientras que en equitabilidad y riqueza no se mostraron diferencias.
CARACTERIZACIÓN FISICOQUÍMICA DE LA MADURACIÓN DEL PLÁTANO DOMINICO-HARTÓN (Musa AAB Simmonds)
Authors: Beltrán-Giraldo Deiby , Velásquez-Téllez John Alexander , Giraldo-Giraldo Germán Antonio 
Published: February 2022

El plátano Dominico Hartón (Musa AAB Simmonds) es de alto impacto económico en el departamento del Quindío, debido a la falta de estudios se realizó la caracterización fisicoquímica del plátano durante la etapa de maduración, el estudio se llevó a cabo con frutos en estado hecho, cosechando a las dieciocho semanas después de floración, se realizó la evaluación poscosecha durante catorce días, haciendo análisis por triplicado de los cambios fisicoquímicos de peso, color, índice de transpiración, índice de respiración, firmeza, pH, acidez, actividad de agua y grados brix. Los resultados demostraron variación de peso cercanas al 25%, en color los rangos para L* fueron entre 53.53 a 63.93, para a* entre -13.19 a 7.91 y para b* entre 34.04 a 49.20, la firmeza paso de 22.78 a 3.41 N/seg., el pH de 5.8 a 4.1, la actividad de agua de 0.997 a 0.962 y los grados brix de 3.0 a 22.2, los parámetros de maduración evidenciaron comportamiento climatérico. Durante la maduración se evidencia perdida de peso, cambio de color, disminución en la firmeza, el pH y la actividad de agua, y un aumento en los grados brix.
Supporting families managing childhood eczema: developing and optimising eczema care online using qualitative research
Authors: Sivyer Katy , Teasdale Emma , Greenwell Kate , Steele Mary , Ghio Daniela , Ridd Matthew J , Roberts Amanda , Chalmers Joanne R , Lawton Sandra , Langan Sinead M , Cowdell Fiona , Le Roux Emma , Wilczynska Sylvia , Williams Hywel C , Thomas Kim S , Yardley Lucy , Santer Miriam , Muller Ingrid 
Published: February 2022

BackgroundChildhood eczema is often poorly controlled owing to underuse of emollients and topical corticosteroids (TCS). Parents/carers report practical and psychosocial barriers to managing their child’s eczema, including child resistance. Online interventions could potentially support parents/carers; however, rigorous research developing such interventions has been limited.AimTo develop an online behavioural intervention to help parents/carers manage and co-manage their child’s eczema.Design and settingIntervention development using a theory-, evidence-, and person-based approach (PBA) with qualitative research.MethodA systematic review and qualitative synthesis of studies (n = 32) and interviews with parents/carers (n = 30) were used to identify barriers and facilitators to effective eczema management, and a prototype intervention was developed. Think-aloud interviews with parents/carers (n = 25) were then used to optimise the intervention to increase its acceptability and feasibility.ResultsQualitative research identified that parents/carers had concerns about using emollients and TCS, incomplete knowledge and skills around managing eczema, and reluctance to transitioning to co-managing eczema with their child. Think-aloud interviews highlighted that, while experienced parents/carers felt they knew how to manage eczema, some information about how to use treatments was still new. Techniques for addressing barriers included providing a rationale explaining how emollients and TCS work, demonstrating how to use treatments, and highlighting that the intervention provided new, up-to-date information.ConclusionParents/carers need support in effectively managing and co-managing their child’s eczema. The key output of this research is Eczema Care Online for Families, an online intervention for parents/carers of children with eczema, which is being evaluated in a randomised trial.
EFEKTIVITAS DAYA HAMBAT ASAP CAIR TEMPURUNG KELAPA (Cocus nucifera) TERHADAP PERTUMBUHAN JAMUR Ganoderma boninense
Authors: Agustina Nur Ariyani 
Published: February 2022

Asap cair mengandung berbagai senyawa yang dapat di kelompokkan ke dalam kelompok senyawa fenol, asam dan kelompok senyawa karbonil. Kelompok-kelompok senyawa tersebut berperanan sebagai anti mikroba, anti oksidan, pemberi flavor dan pembentuk warna. Karena asap cair dapat berperan sebagai anti mikroba dan anti oksigen, maka asap cair dapat digunakan sebagai bahan pengawet. Manfaat asap cair sebagai anti jamur dapat mengendalikan jamur Ganoderma boninense pada kelapa sawit pada busuk pangkal batang. Penelitian ini bertujuan untuk mengetahui manfaat asap cair tempurung kelapa dalam menghambat pertumbuhan jamur Ganoderma boninense. Hasil penelitian ini menunjukkan bahwa pada perlakuan yang paling efektivas menghambat pertumbuhan jamur paling rendah C0 dengan daya hambatnya 0% dan paling tinggi C4 dengan daya hambat 100%. Hal ini menunjukkan bahwa asap cair tempurung kelapa memiliki manfaat dalam menghambat pertumbuhan jamur.
F4/80hi Resident Macrophages Contribute to Cisplatin-Induced Renal Fibrosis
Authors: Sears Sophia M. , Vega Alexis A. , Kurlawala Zimple , Oropilla Gabrielle B. , Krueger Austin , Shah Parag P. , Doll Mark A. , Miller Robert , Beverly Levi J. , Siskind Leah J. 
Published: February 2022

Key Points

Long-term effects of cisplatin are understudied. This study is the first to examine the role of macrophages in cisplatin-induced fibrosis.Depletion of kidney-resident macrophages ameliorated cisplatin-induced fibrosis, whereas depletion of infiltrating macrophages had no effect.This study highlights a pathogenic role for kidney-resident M2 macrophages in the development of fibrosis with repeated nephrotoxic injury.

Background
Cisplatin-induced kidney injury remains a major obstacle in utilizing cisplatin as a chemotherapeutic for solid-organ cancers. Thirty percent of patients treated with cisplatin develop acute kidney injury (AKI), and even patients who do not develop AKI are at risk for long-term declines in kidney function and development of chronic kidney disease (CKD). Modeling cisplatin-induced kidney injury in mice has revealed that repeated low doses of cisplatin lead to development of kidney fibrosis. This model can be used to examine AKI-to-CKD transition processes. Macrophages play a role in some of these processes, including immune response, wound healing, and tissue remodeling. Depleting macrophage populations in the kidney reduced fibrosis development in other models of renal fibrosis.

Methods
We used either C57BL/6 mice with a Ccr2 genetic knockout or liposome encapsulated clodronate (Clodrosome) to deplete macrophage populations during repeated 9 mg/kg cisplatin treatments. We assessed how immune cell populations were altered in the blood and kidney of these mice and how these alterations affected development of renal fibrosis and kidney injury.

Results
We found that Clodrosome treatment decreased collagen deposition, myofibroblast accumulation, and inflammatory cytokine production, whereas Ccr2 genetic knockout had no effect on these markers after cisplatin treatment. Additionally, Ccr2−/− mice had decreased levels of F4/80lo infiltrating macrophages in the kidney after cisplatin treatments, but Clodrosome treatment depleted F4/80hi resident and CD206+ M2 macrophages.

Conclusions
These data suggest that Clodrosome depletion of F4/80hi and M2 macrophages in the kidney attenuates development of renal fibrosis after repeated low doses of cisplatin.
Technologies of "Dry" Chemistry and their Use for Implementation of Express Analysis at the Patient’s Place of Stay (Review of Modern Information)
Authors: Камышников В.С. , Шилейко И.Д. , Алехнович Л.И. 
Published: February 2022

Встатье представлено описание методологии и технологии лабораторного исследования сиспользованием методов «сухой» химии, которые реализуются с применением тест-полосок первого и второго поколения. Изложены современные сведения о конструкции тест-систем разных поколений и об отличительных особенностях совершаемых в них химико-аналитических процессов. Дано представление об оборудовании, используемом для объективной регистрации результатов аналитического исследования. Приведена последовательность его выполнения, обращено внимание на факторы, способные исказить результаты исследования. Охарактеризованы области возможного применения тест-систем для диагностики различных соматических заболеваний. Дано представление о лабораторно-диагностических панелях как сочетаниях показателей лабораторных тестов, традиционно используемых для лабораторной диагностики заболеваний отдельных жизненно важных органов и различных форм инфекционной патологии. Совокупность разных панелей, создаваемых в тест-полосках второго поколения, реализующих иммунохроматографический анализ, составляет своеобразную лабораторию «в кармане», которая может быть использована врачом общей практики непосредственно в месте нахождения пациента.
The article describes the methodology and technology of laboratory research using the methods of "dry" chemistry that are are implemented using test strips of the first and second generation. The modern information about the design of test systems of different generations and the distinctive features of the chemical-analytical processes performed in them is presented. An idea of the equipment used for objective registration of the results of analytical research is given. The sequence of its implementation is given; attention is paid to the factors that can distort the results of the study. The areas of possible application of test systems for diagnostics of various somatic diseases are characterized. An idea is given about the laboratory diagnostic panels as combinations of indicators of laboratory tests traditionally used for laboratory diagnostics of diseases of the vital organs and various forms of infectious pathology. The set of different panels created in the second generation test strips that implement the immunochromatographic analysis makes a kind of "laboratory in a pocket" that can be used by a general practitioner directly at the patient’s location.
Methods of Formation of Oral Speech in Laryngectomized Patients (Literature Review)
Authors: Дайхес Н.А. , Осипенко Е.В. , Орлова О.С. , Исаева М.Л. , Котельникова Н.М. , Михалевская И.А. , Кривых Ю.С. 
Published: February 2022

Среди злокачественных новообразований лор-органов рак гортани занимает первое место. Несмотря на то что гортань доступна для осмотра, 65-70% случаев заболевания выявляются на III-IV стадиях. Лечение данной категории пациентов носит комбинированный, или комплексный, характер, одним из этапов которого является ларингэктомия. Ларингэктомия приводит к инвалидизации пациента, потере голосовой функции. Часть пациентов отказывается от хирургического вмешательства именно по причине перспективы утраты голосовой функции. Поэтому в социальной реабилитации пациентов с раком гортани важное место занимает восстановление устной речи. Без реабилитационных мероприятий ларингэктомированные пациенты лишаются возможности не только трудиться, но и вообще находиться в обществе. Встатье приведен обзор научной литературы, посвященной проблеме восстановления устной речи у пациентов, перенесших ларингэктомию. В исторической ретроспективе показано развитие трех наиболее распространенных и активно применяемых на практике способов голосоречевой реабилитации ларингэктомированных пациентов. В работах отечественных и зарубежных исследователей изучены подходы и различные методики при послеоперационной реабилитации звучной речи как одного из факторов восстановления идентичности личности человека и его положения в обществе.
Laryngeal cancer ranks first among the malignant neoplasms of the ENT organs. Despite the fact that the larynx is accessible for examination, the disease is detected at the stages III-IV in 65-70% of cases. Treatment of this category of patients is combined or complex, and one of the stages is laryngectomy. Laryngectomy leads to disability of the patient, loss of voice function. Some patients refuse surgery due to the possibility of voice loss. Therefore, the restoration of oral speech plays an important role in rehabilitation of patients with laryngeal cancer. Laryngectomized patients can not only work, but generally socialize without rehabilitation measures. The article provides the review of scientific literature on the problems of oral speech restoration in patients that underwent laryngectomy. Historical overview shows the development of the three most common and actively used in practice methods of voice-speech rehabilitation of laryngectomized patients. The works of local and foreign researchers show approaches and various methods of postoperative rehabilitation of sonorous speech as one of the factors in restoring the person’s identity and their position in society.
Modelling Orbital Wall Injuries and Determining Dimensional and Geometric Parameters of Bone Defects in Rabbits
Authors: Красильникова В.Л. , Дудич О.Н. , Осипович В.С. , Абельская И.С. 
Published: February 2022

В исследование было включено 40 кроликов, которые составили две группы (контрольную синтактной орбитой и основную с сформированным дефектом орбиты и имплантацией титановой конструкции (имплантата) для устранения дефекта орбиты). При знании особенностей анатомии орбиты кролика она является одной из доступных и хороших моделей для построения хирургической модели повреждений орбиты.
Forty rabbits were equally divided into control group with an intact orbit and the main group with orbital defect and titanium implant that eliminates the orbital defect. With knowledge of the rabbit’s orbit anatomy, this model is suitable for the surgical modelling of orbital injuries.
Improvement of Diagnostics and Treatment of Ophthalmic Complications in Zygomatic and Orbital Injuries
Authors: Агзамова С.С. 
Published: February 2022

Целью нашего исследования явилось изучение офтальмологической симптоматики у пациентов с переломами скуло-орбитального комплекса, развития травматической оптической нейропатии (ТОН) в зависимости от гемодинамических нарушений. Материалы и методы: с 01.09.2015 по 01.09.2019 в отделение челюстно-лицевой хирургии госпитализировано 3013 пациентов с черепно-мозговой травмой, из них у 821 диагностированы различные переломы костей средней зоны лица. Результаты. Ведущими офтальмологическими симптомами травм скуло-орбитального комплекса являются: энофтальм, ограниченное движение глазных яблок, диплопия. Травматическая оптическая нейропатия при данной патологии встречается в 20,9% случаев. Своевременное выполнение реконструктивных операций на раннем этапе позволяет восстановить функциональные расстройства: дистопию - в 89,8% случаев, исправление страбизма - 73,6%, диплопию - 91,5% - и получить хорошие косметические результаты.
Purpose: The aim of our study was to study the ophthalmological symptoms in patients with fractures of the zygomatic-orbital complex in craniocerebral trauma, the development of TONS depending on hemodynamic disorders. Materials and methods: From 01.09.2015 to 01.09.2019, 3013 patients with craniocerebral trauma were hospitalized in the department of maxillofacial surgery, of which 821 were diagnosed with various fractures of the bones of the middle zone of the face. Results: The leading ophthalmological symptoms of injuries of the zygomatic-orbital complex are: enophthalmos, limited movement of the eyeballs, diplopia. Traumatic optical neuropathy in this pathology occurs in 20.9%. Timely implementation of reconstructive operations at an early stage allows you to restore functional disorders: dystopia in 89.8% of cases, strabismus correction in 73.6%, diplopia-in 91.5% and get good cosmetic results