bluuebunny/crossref_metadata_2025_split huggingface dataset:
Alfabetización Digital. Un ejercicio para la construcción de Paz desde la Localidad de Suba (Bogotá, Colombia)
Authors: Díaz Vásquez Rafael Francisco , Bejarano Pérez Juan Pablo 
Published: August 2022

Objetivo: El presente trabajo tuvo como objetivo plantear el uso de las TIC como estrategia de democrática para la construcción de Paz en Colombia, a partir de un estudio de caso
Originalidad/aporte: El proyecto desarrollado tuvo como la puesta en marcha de un proceso de investigación que ha contado con etapas desde 2016 hasta 2019, financiado por diferentes instituciones como entidades locales (Alcaldía Local de Suba, Proyecto 240 de 2016), Fundación Tortuga, el Centro de Estudios Sociedad y Espacio y el Politécnico Grancolombiano, en el cual se puedo verificar la incorporación de experiencias de aprendizaje fuera del aula mediante el uso de TIC
Método: El trabajo se desarrolló mediante la Investigación Acción Participativa –IAP, con la población de la localidad de Suba, contando una serie de experiencias que permiten establecer cuáles son los usos, experiencias y acciones por mejorar en cuanto al uso de las Tecnológicas de la Información y Comunicación y el acceso a los dispositivos electrónicos en una muestra de población, lo que permitió, desarrollar un proceso de “Alfabetización Digital”.
Estrategias/recolección de información: Se puedo realizar una recolección de información a partir de datos nacionales y locales del uso de TIC, así como la recolección d ellos mismos por parte del proyecto en la localidad de Suba, permitiendo revalidar y en algunos casos la verdadera inserción de las TIC dentro de la población de una muestra considerable de estratos de localización urbana.

Conclusiones: El análisis de resultados que se expone comprende la incorporación de experiencias de aprendizaje en el aula, permitiendo establecer los usos de las TIC, dado que generalmente se considera el uso de los procesos de aprendizaje mediante el uso de las TIC, dentro del aula como una herramienta en la didáctica del aprendizaje. En este caso, la exposición de resultados y análisis presentados comprende cómo fuera del aula en Colombia, se encuentra una gran parte de población que puede utilizar las TIC para los procesos de aprendizaje, para lo que es necesario, establecer procesos que denominamos dentro de nuestra propuesta como “Alfabetización Digital”.
Por una educación rural inclusiva y real: apreciaciones de Ramiro Guerra Sánchez
Authors: Pereira Castellón Adrián Francisco 
Published: August 2022

Objetivo: El artículo tiene como objetivo caracterizar, a partir de la percepción de Ramiro Guerra, la problemática educativa de la población campesina cubana en la década de 1940. Periodo en el cual, la sociedad rural recibe especial atención y se promueven proyectos para las escuelas primarias superiores.
Originalidad/aporte: Consideramos esta investigación relevante porque muestra, a través del pensamiento y la biografía de un personaje poco investigado, una de las manifestaciones de enajenación del campesinado cubano, que sería fundamento para las luchas sociales y políticas desarrolladas por los movimientos progresistas y revolucionarios cubanos entre los años 40 y 50 del siglo pasado.
Método: En el trabajo se emplea la investigación documental, biográfica, y hemerográfica debidamente asentadas en los métodos histórico – lógico y analítico - sintético. Se realiza la reconstrucción de algunos aspectos biográficos sobre Ramiro Guerra Sánchez en relación con el contexto en que actuó. Esto solo fue posible mediante la consulta de repositorios de colecciones documentales públicos que permiten el acceso a fuentes hemerográficas.
Estrategias de recolección de información: búsqueda y organización de documentos procedentes de la Biblioteca Nacional de Cuba y la Colección digital de la Universidad de la Florida.
Conclusión: este artículo permite la caracterización de la situación educacional en la población rural cubana de la década de los años 40 del pasado siglo y permite, además, profundizar en el análisis de de las ideas educativas que Ramiro Guerra aportó a dicho segmento social. Es también una oportunidad para aquilatar el progresismo del pensamiento de Guerra Sánchez.
Analisis Kesulitan Belajar Membaca Permulaan Siswa Kelas II pada Mata Pelajaran Bahasa Indonesia di Madrasah Ibtidaiyah Munawariyah Palembang
Authors: Oktadiana Bella 
Published: July 2022

Kesulitan belajar membaca permulaan merupakan kesulitan belajar membaca pada anak tingkat sekolah dasar kelas II akhrinya terjadi pada siswa tertentu, oleh karena itu kesulitan belajar membaca permulaan lebih diperhatikan oleh guru bahasa Indonesia. Permasalahan dalam penelitian ini adalah kesulitan belajar membaca permulaan siswa kelas II.B pada mata pelajaran bahasa Indonesisa, dan faktor-fakor kesulitan belajar membaca permulaan siswa di kelas II.B pada mata pelajaran bahasa Indonesia di Madrasah Ibtidaiyah Munawariyah Palembang, tujuan penelitian ini adalah untuk mengetahui kesulitan belajar membaca permulaan siswa kelas II.B pada mata pelajaran bahasa Indonesisa dan untuk mengetahui faktor-faktor penyebab kesulitan membaca permulaan siswa kelas II.B pada mata pelajaran bahasa Indonesia di Madrasah Ibtidaiyah Munawariyah Palembang. Jenis penelitian ini adalah deskriptif kualitatif, informen penelitian ini adalah siswa kelas II.B. Ada pun alat pengumpulan data dalam penelitian ini berupa observasi, wawancara dan dokumentasi. Sedangkan data yang telah dikumpulkan kemudian dianalisis dengan teknik analisis data deskriptif kualitatif yaitu reduksi data, penyajian data dan penarikan kesimpulan (verifikasi). Hasil penelitian ini adalah pertama, analisis kesulitan belajar membaca permulaan yang dialami siswa kelas II.B pada mata pelajaran bahasa Indonesia adalah analisis kesulitan siswa mengeja huruf menjadi suku kata, analisis kesulitan siswa mengeja suku kata menjadi kata, dan analisis kesulitan siswa membedakan huruf b-d, p-q. Dan yang kedua faktor-fakor penyebab kesulitan belajar membaca permulaan siswa di kelas II.B pada mata pelajaran bahasa Indonesia di Madrasah Ibtidaiyah Munawariyah Palembang yaitu yang pertama faktor dari peserta didik itu sendiri yaitu faktor fisik, inteligensi, minat, motivasi, yang kedua faktor dari guru yaitu pengelolaan kelas yang kurang efektif, dan yang ketiga faktor dari keluarga yaitu kurangnya dukungan kepada anak di rumah.
Pengendalian Inventory Berdasarkan Klasifikasi Bahan Consumable Di PT UVW
Authors: Sibarani Ayu Anggraeni , Riza Muthia Atikah , Adhiana Tigar Putri 
Published: July 2022

<p>Bahan <em>consumable</em> menjadi hal yang penting dalam suatu proses produksi pada PT.UVW. Kekurangan atau keterlambatan kedatangan bahan <em>consumable</em> ini akan berdampak pada mundurnya proses produksi sehingga konsumen akan menerima produk tidak pada waktu yang telah ditentukan. Hal ini tentunya berdampak negatif pada perusahaan, diantaranya kehilangan kepercayaan serta loyalitas konsumen, dan dari sisi ekonomi perusahaan akan kehilangan keuntungan. Salah satu upaya yang dapat dilakukan untuk menjaga ketersediaan bahan <em>consumable</em> adalah dengan melakukan pengendalian persediaan yang baik. Pengendalian persediaan yang dilakukan pada penelitian ini menggunakan metode <em>Continuous Review System</em> dengan penggabungan analisis FSN-SDE (CFSNSDE). Berdasarkan hasil pengolahan data, bahan <em>consumable</em> yang digunakan pada PT. UVW dapat diklasifikasikan menjadi kategori FS sebanyak 2 bahan, kategori FD sebanyak 1 bahan, kategori FE sebanyak 1 bahan, kategori SS sebanyak 6 bahan, dan kategori NS sebanyak 11 bahan. Perhitungan terhadap total biaya persediaan usulan dengan pendekatan <em>Continuous Review System</em> menghasilkan total biaya sebesar Rp 94.662.206. Penelitian ini menunjukan bahwa <em>Continuous Review System</em> dapat menurunkan total biaya persediaan sebesar 84,39% dari yang semula bernilai Rp 865.225.864</p>
Evaluation, Characterization of Fiber Content, and Antioxidant Activity of Corncob (Zea mays L.) during Alkalization
Authors: Suryanto Edi , Taroreh Mercy I.R. 
Published: July 2022

Corncob fiber powder was prepared by alkaline process, and their effects were investigated on the composition, physicochemical, and antioxidant properties of dietary fiber (DF) products. DF content was determined using AOAC enzymatic-gravimetric analysis,
while chemical composition in fiber was observed on
cellulose, hemicellulose, and lignin. The results showed that cellulose content of significantly increased while hemicellulose and lignin was observed decreasing. Correspondingly, content of the insoluble, soluble, and total DF of corncob was increased by 14.72-20.77, 28.86-47.43, and 15.12-21.42%, respectively. Furthermore, the particle size of DF is distributed in a range from 58.50-83.90 µm. XRD analysis showed the characteristics of cellulose that exhibited increasing crystalline degree from 29.33% to 53.53% and 59.62%, respectively. FTIR shows that the DF matrix structure does not change and in the presence of special structures of cellulose compounds. The SEM results showed that the alkaline process could significantly decrease the particle size and influence on the physicochemical and functional properties of corncob insoluble DF. The results also showed that DF extract has lower DPPH radical scavenging activity. The results suggest that corncob DF have good potential candidate for dietary fiber containing antioxidant ingredient and for their further applications in food.
RAPD Profiles of Rhynchostylis gigantea (Lindl.) Ridl. Collected from Puspa Nirmala Orchids Banyumas, Central Java
Authors: Susanto Agus Hery , Romadhoni Ali , Dwiati Murni 
Published: July 2022

Rhynchostylis gigantea (Lindl.) Ridl. is an orchid species spread over Southeast Asia countries. This species is very popular among ornamental plant collectors, especially due to its densely pack inflorescences. Hence, it is commercially found in many ornamental plant nursuries, such as Puspa Nirmala Orchids Banyumas, Central Java. Further development of the species should be supported by scientific data, particularly regarding the genetic variation. One of the molecular markers commonly used to study genetic variation is Random Amplified Polymorphic DNA (RAPD). This study aims to assess genetic variation of R. gigantea cultivars of Puspa Nirmala Orchids Banyumas collection by RAPD profiles. Genomic DNAs were extracted from leaf samples of eight R. gigantea individuals, while RAPD markers were amplified using five random primers (OPA-15, OPK-16, OPP-15, OPP-08 and OPO-08). Descriptive analysis was employed on the data obtained. It was revealed that all of the primers resulted in a 100% monomorphism. This indicates an extremely low genetic variation among R. gigantea population of Puspa Nirmala Orchids collection, which is probably due to the same origin from a selected hybrid of the same crosses.
Kecanduan Smartphone dan Stres Akademik di Masa Pandemi : Sebuah Studi Potong Lintang
Authors: Sumiyarini Retno , Yuliyani Amini 
Published: July 2022

<p><strong>ABSTRAK</strong></p><p><strong>Pendahuluan : </strong>Kecanduan <em>smartphone </em>merupakan perilaku terlalu lama menggunakannya tanpa melihat dampak negatif sehingga akan berpengaruh terhadap kesehatan. Kecanduan smarphone dipicu perubahan pembelajaran di masa pandemi yang mengharuskan mahasiswa banyak mengakses <em>smartphone</em>. Selain itu banyak mahasiswa yang merasakan stres karena ketidakmampuan adaptasi dengan situasi membuat mereka mencari pelampiasan, salah satunya adalah dengan bermain smartphone. Latar belakang tersebut mendorong penelitian ini yang bertujuan mengetahui hubungan kecanduan <em>smartphone </em> dengan stres akademik di masa pandemi pada mahasiswa keperawatan Universitas Jenderal Achmad Yani Yogyakarta.</p><p><strong>Metode: </strong>Penelitian ini merupakan penelitian kuantitatif dengan pendekatan <em>cross sectional</em>. Penelitian ini dilaksanakan pada bulan Februari-Juni 2022. Populasi dalam penelitian ini yaitu mahasiswa keperawatan Universitas Jenderal Achmad Yani Yogyakarta. Dengan responden sejumlah 96 orang. Instrumen yang digunakan yaitu <em>smartphone addiction scale </em>dan <em>academic stress scale</em>. Analisis data menggunakan univariat dan bivariat dengan uji <em>Gamma.</em><em></em></p><p><strong>Hasil dan pembahasan: </strong> Mayoritas responden (69,8%) mahasiswa mengalami kecanduan <em>smartphone </em>pada level sedang dengan stress akademik yang terbanyak berada pada level sedang (70,8%). Selain itu, penelitian ini membuktikan bahwa stress akademik memiliki korelasi positif dengan kecanduan <em>smartphone </em>dengan nilai signifikasi P = 0,000</p><p><strong>Kesimpulan: </strong>Stress akademik memiliki korelasi yang bermakna dengan kecanduan<em> smartphone. </em></p><p><strong>Kata Kunci: Kecanduan Smartphone, Stres Akademik.</strong></p>
Curcumin ameliorate cortical histomorphological deficits in Streptozocin and western diet induced neurodegeneration in Wistar Rats
Authors: Mohammed Abdullahi Abiodun , Akinola Oluwole Busayo 
Published: August 2022

Abstract
We employed a rodent model to typify histomorphological changes connected to dementia-like symptoms and co-morbid insulin resistance; we examined neuronal density and morphological changes in the neurons of the prefrontal cortex (PFC); evaluated amyloid beta (Aβ) deposits and probed the association between phosphatidylinositol 3-kinase (PI3K), serine/threonin protein kinase (AKT) and glycogen synthase kinase 3β (GSK3β) activity and oral curcumin regimen. 36 adult Wistar rats were randomized into six groups (n=6) and treated with: (olive oil) control group; (curcumin) for positive control; High Fat Diet (HFD) and three doses of Streptozotocin (STZ) for diabetic; (HFD, three doses of STZ and concurrent curcumin) preventive; (pre-treatment with curcumin, followed by HFD and three doses of STZ) protective group; (HFD, three doses of STZ followed by curcumin) for therapeutic group. Cortical sections were stained for histological and histochemical investigations. ELISA was used for quantifying PI3K, AKT and GSK3β activity. Data was analyzed using one-way ANOVA and Turkey’s post hoc test. p<0.05 was considered significant. Findings indicate that oral curcumin significantly reduced blood glucose and insulin resistance. Insulin resistance was associated with cyto-architectural deficits observed in the PFC, while curcuminn ameliorated observed changes; furthermore, Oral curcumin reduced Aβ deposits in the PFC of the model. The impaired activity of PI3K, AKT and GSK-3β of the model was ameliorated by oral curcumin. The study concluded that oral curcumin showed ameliorative potentials on the PFC of adult male Wistar rats against neuronal death associated with dementia and insulin resistance.
Distribution of Pfmdr 1 and Kelch 13 Genes among the Children 5 Years and Below Attending a Secondary Health Facility in Akure, South-West, Nigeria.
Authors: AFOLABI OLAJIDE JOSEPH , Oluwafemi Olubanke Rosena , Oniya Mobolanle Oladipo 
Published: August 2022

Abstract
Background: Malaria parasite resistant has been a major barrier to effective treatment of malaria. Therefore, the study aimed to evaluate the distribution of P. falciparum resistant kelch protein gene on chromosome 13 (Kelch 13) and multidrug resistant (Pfmdr1) mutant genes among children aged five years and below who attended Mother and Child Hospital, Akure, Nigeria. Methods: Thin and thick smears were prepared from the blood collected aseptically through venepuncture from five hundred (500) children. Structured questionnaires were used to obtain demographic data from the respondents. Two hundred malaria positive samples were randomly selected from the 500 samples for PCR analysis to detect Pfmdr1 and Kelch 13 mutant genes. Results: The results showed that of the 500 respondents, 288 (57.6%) were males while 212 (42.4%) were females. Pfmdr1distribution include: mixed group (mutant/wild) 38.5%, mutant gene 35.5%, wild gene 20.5% and the resistant genes were absent in 5.5% of the infected children. The mixed group of Pfmdr1 gene was higher among infants (51.9%), children with birth order 4 (60.0%) and children that have blood group B (51.3%), however, there is no significant difference in the distribution of Pfmdr1 between gender (χ2 = 0.634, df = 1, p>0.05). There was a point mutation in the codon position 557 where the amino acid Alanine was replaced by Serine in the PfK13.Conclusions: The presence of Pfmdr1 mutant genes and point mutation in the PfK13 gene of P. falciparum among children, calls for development of innovative drugs targeted on these resistant strains.
An Augmented Reality Assistance System to See-Through Vehicle Components
Authors: Poschke Alexander , Jütte Lukas , Küster Benjamin , Overmeyer Ludger 
Published: July 2022

Abstract
Limited visibility during the operation of forklifts is one of the most significant sources of danger in in-plant material handling. Existing systems record concealed areas via cameras and display them directly on monitors in the driver's cab. Augmented reality (AR) allows to display information directly in the driver's field of view (FoV). Concealed areas could thus be overlaid with the camera images, while nothing is displayed in areas with a clear view, allowing the real environment to be perceived. This research aims to demonstrate the suitability of AR as an assistance system for forklifts. The assistance system combines various sensors for pose determination, RGB-D cameras for environment recording and a head-mounted display (HMD) for visualization. We define requirements from a safety perspective and classify our system with respect to these requirements. The results show the suitability of AR technology as a driver assistance system. At the same time, they show challenges in accuracy and latency.
Multi-perspective comparison of the immune microenvironment of primary colorectal cancer and liver metastases
Authors: He Yangsong , Li Danxiu , Fan A-hui , Wang Boda , Ji Kun , Wang Xin , Zhao Xiaodi , Lu Yuanyuan 
Published: August 2022

Abstract
Background Liver metastases are a major contributor to the poor immunotherapy response in colorectal cancer patients. However, the distinctions in the immune microenvironment between primary tumors and liver metastases are poorly characterized. The goal of this study was to compare the expression profile of multiple immune cells to further analyze the similarities and differences between the microenvironments of liver metastases and the primary tumor. Methods Tissues from 17 patients with colorectal cancer who underwent resection of primary and liver metastases was analyzed using multispectral immunofluorescence. The expression of multiple immune cells (CD8, Foxp3, CD68, CD163, CD20, CD11c, CD66b, CD56, PD-L1, INF-γ, Ki67 and VEGFR-2) in the tumor center (TC), tumor invasive front (<150 µm from the tumor center, TF) and peritumoral region (≥150 µm from the tumor center, PT) was evaluated via comparison. The expression of CD68 and CD163 in different regions was further analyzed based on the cell colocalization method. In addition, different immune phenotypes were studied and compared according to the degree of CD8 infiltration.Results The expression trends of 12 markers in the TF and TC regions were basically the same in the primary tumor and liver metastasis lesions. However, in comparison of the TF and PT regions, the expression trends were not identical between primary and liver metastases, especially CD163, which was more highly expressed in the PT region relative to the TF region. In the contrast of different space distribution, the expression of CD163 was higher in liver metastases than in the primary foci. Further analysis of CD68 and CD163 via colocalization revealed that the distribution of macrophages in liver metastases was significantly different from that in the primary foci, with CD68-CD163+ macrophages predominating in liver metastases. In addition, among the three immunophenotypes, CD163 expression was highest in the immune rejection phenotype. Conclusions The immune cells found in the primary tumors of colorectal cancer differed from those in liver metastases in terms of their spatial distribution. More immunosuppressive cells were present in the liver metastases, with the most pronounced differential distribution found for macrophages. CD68-CD163+ macrophages may be associated with intrahepatic immunosuppression and weak immunotherapeutic effects.
Bioactivity and mechanical properties characterization of bioactive glass incorporated with graphene oxide
Authors: El-khooly M. S. , Abdraboh A. S. , Baker A. M. , Ereiba KH. T. 
Published: August 2022

Abstract
In this study, the bioactivity and the mechanical properties (Mechanical compressive stresses, Hardness, and density) of bioglass (BG) and bioglass/graphene oxide (BG/GO) were investigated. Bioglass in chemical composition [60SiO2_35CaO_5P2O5] was prepared via the sol-gel method. GO was added to the bioglass (BG) with different contents (0.5, 1, 2, and 3) wt.% named as 0.5%GO, 1%GO, 2%GO, and 3%GO samples respectively. The synthesized specimens were characterized by several techniques (FT-IR, XRD, and SEM). Compressive stresses, Hardness, and density were studied also by different techniques to obtain the optimum Mechanical samples. The biological activity was studied by an in-vitro test in simulated body fluid (SBF) for 33 days. Results showed that: the 0.5%GO sample exhibited optimum mechanical compressive strength by approximately 82% compared to the BG sample. Hardness was increased from 0.5%GO sample up to 1%GO sample compared to BG sample and gradually decreased in 2%GO Sample and 3%GO. Bioactivity results showed deposition of HA layer on the bioglass surface and there was no significant change in it with the addition of graphene oxide.
Research on the impact resistance of periodic multilayer helical bionic structure based on osteon microstructure
Authors: Liu Yuxi , Li Aihua , Li Yanhua , Chen Song 
Published: August 2022

Abstract
It is found that the osteon is composed of thin and thick lamellae which are periodic and approximately concentric, every 5 lamellae is a cycle, the periodic helix angle of mineralized collagen fibers in two adjacent sub-lamellae is 30°. Four bionic composite models with different fiber helix angles were established and fabricated according to the microstructure of mineralized collagen fibers in osteon. Based on the impact analysis of four kinds of bionic composite models, the effects of the fiber periodic spiral structure on the impact resistance and energy dissipation of multi-layer bionic composite were investigated. The analysis results show that the fiber helix angle affects the impact damage resistance and energy dissipation of multi-layer fiber reinforced composites. Among the four kinds of multi-layer composite models, the composite model with helix angle of 30° has better comprehensive ability to resist impact damage. The test results show that the impact damage area of the specimen with 30° helix angle is smallest among the four types of bionic specimens, which is consistent with the results of finite element impact analysis. Furthermore, in the case of without impact damage, the smaller the fiber helix angle is, the more uniform the stress distribution is and more energy is dissipated in the impact process. The periodic spiral structure of mineralized collagen fibers in osteon are the result of natural selection of biological evolution. This structure can effectively improve the ability of cortical bone to resist external impact. The research results can provide useful guidance for the design and manufacture of high-performance and strong impact resistant bionic composites.