bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of thyroid function in female and male infertility: a narrative review
Authors: Mazzilli R. , Medenica S. , Di Tommaso A. M. , Fabozzi G. , Zamponi V. , Cimadomo D. , Rienzi L. , Ubaldi F. M. , Watanabe M. , Faggiano A. , La Vignera S. , Defeudis G. 
Published: August 2022

Abstract
Purpose
We herein aimed to review the new insights into the impact of impaired thyroid function on male and female fertility, spacing from spontaneous pregnancy to ART, with the objective of providing an updated narrative revision of the literature.

Methods
This narrative review was performed for all available prospective, retrospective and review articles, published up to 2021 in PubMed. Data were extracted from the text and from the tables of the manuscript.

Results
Thyroid dysfunction is frequently associated with female infertility, whereas its link with male infertility is debated. Female wise, impaired function is detrimental to obstetric and fetal outcomes both in spontaneous pregnancies and in those achieved thanks to assisted reproduction technologies (ART). Furthermore, the reference range of TSH in natural pregnancy and ART procedures has recently become a matter of debate following recent reports in this field. On the other hand, the impact of thyroid function on the male reproductive system is less clear, although a possible role is suggested via modulation of Sertoli and Leydig cells function and spermatogenesis.

Conclusion
Thyroid function should be carefully monitored in both male and female, in couples seeking spontaneous pregnancy as well as ART, as treatment is generally immediate and likely to improve chances of success.
Salute ossea in corso di trattamento adiuvante anti-ormonale nella patologia oncologica: rischio fratturativo e temporizzazione della terapia
Authors: Pisarro Morena , Conti Francesco 
Published: August 2022

SommarioLe alterazioni della densità ossea e le fratture da fragilità sono frequenti complicanze della terapia ormonale adiuvante in pazienti affetti da carcinoma della mammella e carcinoma prostatico, a causa dell’effetto negativo dell’ipoestrogenismo e della deprivazione androgenica sull’osso. La valutazione del rischio fratturativo in questi pazienti e la corretta gestione delle complicanze ossee dovute alla terapia adiuvante risultano di fondamentale importanza sia per la riduzione degli eventi fratturativi, sia per il miglioramento della qualità della vita.
Artificial intelligence in the long view: from mechanical intelligence to cyber-social systems
Authors: Cope Bill , Kalantzis Mary 
Published: August 2022

AbstractArtificial intelligence (AI) is emerging as a defining technology of our time, a source of fear as often as inspiration. Immersed in its practicalities, rarely do we get to ask the question, what is it? How does it impact our lives? How does it extend our human capacities? What are its risks? What are its limits? This paper is a theoretical and historical overview of the nature of binary computing that underpins AI and its relations with human intelligence. It also considers some philosophical questions about the semiotic or sense-creating work of computers. Our argument proceeds in five steps. We begin with an historical background: since Ada Lovelace, we have wondered about the intelligence of machines capable of computation, and the ways in which machine intelligence can extend human intelligence. Second, we ask, in what ways does binary computing extend human intelligence and delimit the scope of AI? Third, we propose a grammar with which to parse the practical meanings that are enabled with and through binary computing. Through this discussion, we raise the question of ontology as a counter-balance to what we will argue has been an over-emphasis on the instrumental reasoning processes of the algorithm. Fourth, we situate binary computing in the context of broad developments in modern societies which we characterize as a series of systems transitions: from industrial, to informational, to a new phase that we term “cyber-social.” Finally, we explore the risks inherent in a pervasively cyber-social system. These are narrowly captured in the technical domain, “cybersecurity.” We set out to reconceive this problem framework as the location for a potential solution, supplementing analyses of cybersecurity risk with a program of cyber-social trust.
Effective equidistribution of horospherical flows in infinite volume rank-one homogeneous spaces
Authors: TAMAM NATTALIE , WARREN JACQUELINE M. 
Published: August 2022

AbstractWe prove effective equidistribution of horospherical flows in
$\operatorname {SO}(n,1)^{\circ } / \Gamma $
when
$\Gamma $
is geometrically finite and the frame flow is exponentially mixing for the Bowen–Margulis–Sullivan measure. We also discuss settings in which such an exponential mixing result is known to hold. As part of the proof, we show that the Patterson–Sullivan measure satisfies some friendly like properties when
$\Gamma $
is geometrically finite.
A probabilistic model for interfaces in a martensitic phase transition
Authors: Cesana Pierluigi , Hambly Ben M. 
Published: August 2022

AbstractWe analyse features of the patterns formed from a simple model for a martensitic phase transition that fragments the unit square into rectangles. This is a fragmentation model that can be encoded by a general branching random walk. An important quantity is the distribution of the lengths of the interfaces in the pattern, and we establish limit theorems for some of the asymptotics of the interface profile. In particular, we are able to use a general branching process to show almost sure power law decay of the number of interfaces of at least a certain size and a general branching random walk to examine the numbers of rectangles of a certain aspect ratio. In doing so we extend a theorem on the growth of the general branching random walk as well as developing results on the tail behaviour of the limiting random variable in our general branching process.
“Nothing to see here”: No structural brain differences as a function of theBig Fivepersonality traits from a systematic review and meta-analysis
Authors: Chen Yen-Wen , Canli Turhan 
Published: August 2022

AbstractPersonality reflects social, affective, and cognitive predispositions that emerge from genetic and environmental influences. Contemporary personality theories conceptualize a Big Five Model of personality based on the traits of neuroticism, extraversion, agreeableness, conscientiousness, and openness to experience. Starting around the turn of the millennium, neuroimaging studies began to investigate functional and structural brain features associated with these traits. Here, we present the first study to systematically evaluate the entire published literature of the association between the Big Five traits and three different measures of brain structure. Qualitative results were highly heterogeneous, and a quantitative meta-analysis did not produce any replicable results. The present study provides a comprehensive evaluation of the literature and its limitations, including sample heterogeneity, Big Five personality instruments, structural image data acquisition, processing, and analytic strategies, and the heterogeneous nature of personality and brain structures. We propose to rethink the biological basis of personality traits and identify ways in which the field of personality neuroscience can be strengthened in its methodological rigor and replicability.
Intergenerational Social Mobility, Political Socialization and Support for the Left under Post-industrial Realignment
Authors: Ares Macarena , van Ditmars Mathilde M. 
Published: August 2022

AbstractThis article investigates how class of origin and intergenerational social mobility impact left-wing party support among new and old core left-wing electorates in the context of post-industrial electoral realignment and occupational transformation. We investigate the remaining legacy of political socialization in class of origin across generations of voters in the UK, Germany and Switzerland. We demonstrate that part of the contemporary middle-class left-wing support is a legacy of socialization under industrial class–party alignments, as many individuals from working-class backgrounds – traditional left-wing constituencies – have a different (post-industrial) class location than their parents. These enduring effects of production worker roots are weaker among younger generations and in more realigned contexts. Our findings imply that exclusively considering respondents' destination class underestimates the relevance of political socialization in class of origin, thereby overestimating electoral realignment. However, these past industrial alignments are currently unparalleled, as newer left-wing constituencies do not (yet) demonstrate similar legacies.
Fluid evolution and ore genesis of Cu–Pb–Zn veins in the Panjiaduan deposit, Great Xing’an Range, NE China: evidence from fluid inclusion and H–O–He–Ar isotopes
Authors: Sun Qing-Fei , Wang Ke-Yong , Sun Feng-Yue , Zhang Miao , Zhao Chen-Guang , Sun Li-Xue 
Published: August 2022

AbstractThe southern Great Xing’an Range (SGXR), located in the eastern segment of the Central Asian Orogenic Belt (CAOB), is one of the most economically important Cu–Mo–Fe–Sn–Pb–Zn–Ag metallogenic provinces in China. The newly discovered Panjiaduan Cu–Pb–Zn deposit (9.3 Mt; at 1.36% Cu, 2.90% Pb, 3.80% Zn and 38.12 g/t Ag), located in the SE segment of the SGXR, is primarily hosted in fracture zones in volcanic rocks and granodiorite of the Manitu Formation. Four paragenetic stages of metallic mineralization are identified: (I) quartz-pyrite-arsenopyrite; (II) quartz-polymetallic sulphide; (III) quartz-galena-sphalerite-argentite; and (IV) quartz-calcite-minor sulphide. The hydrothermal quartz contains three types of primary fluid inclusion (FIs): vapour-rich two-phase liquid-vapour (LV-type), liquid-rich two-phase liquid-vapour (VL-type) and three-phase liquid-vapour-solid FIs (SL-type). Stages I and II contain all types with homogenization temperatures (Th) of 324–386 °C and 276–334 °C as well as salinities of 0.7–38.0 wt% and 0.9–34.7 wt%, respectively, whereas stage III is composed of VL- and LV-type FIs with Th of 210–269 °C and salinities of 0.5–7.2 wt%. Only VL-type FIs occur in stage IV, with Th of 139–185 °C and salinities of 1.6–4.2 wt%. The δ18OH2O and δD values vary from −15.7 to 2.6‰ and −132.7 to −110.2‰, respectively, indicating predominant meteoric water with an initial magmatic source. The He–Ar isotopic compositions of the pyrite inclusions from the Panjiaduan Cu–Pb–Zn veins suggest that fluids were derived from the crust.
Credit claiming and mayoral preferences for project uptake amid a migrant crisis
Authors: Bello-Gomez Ricardo A. , Avellaneda Claudia N. 
Published: August 2022

AbstractWhen considering taking over public projects, executives assess their perceived credit-claiming opportunities against potential blame attribution. The balance of these perceptions may shift under crisis. Meanwhile, the literature has mostly explored project uptake in delegation contexts when decisionmakers hold certain control powers over delegees, but not when such controls are absent. Amid one of the largest migrant crises worldwide, we conducted a survey experiment with 238 sitting Colombian mayors. We explore issue visibility, salience of project beneficiaries, and policy stage (formulation versus implementation) as drivers of mayors’ preferences for project uptake or cession to upper-level governments. Results reveal mayors are less likely to cede implementation to the national government when presented with a more visible project. Neither visibility nor beneficiaries’ salience affects mayoral preferences for project formulation on its own. However, mayors are less likely to delegate both formulation and implementation when beneficiaries are more salient to their constituents.
Mapping parents’ journey following prenatal diagnosis of CHD: a qualitative study
Authors: Harris Kelly W. , Hammack-Aviran Catherine M. , Brelsford Kathleen M. , Kavanaugh-McHugh Ann , Clayton Ellen Wright 
Published: August 2022

AbstractObjective:To better understand parents’ accounts of their prenatal and postnatal experience after prenatal diagnosis of CHD – particularly emotional processing and coping mechanisms – to identify strategies to improve support.Methods:This single-centre, longitudinal qualitative study included pregnant mothers and their support persons seen in Fetal Cardiology Clinic at Vanderbilt Children’s Hospital from May through August 2019 for probable complex CHD. Twenty-seven individuals from 17 families participated in 62 phone interviews during pregnancy and postpartum: 27 conducted after the initial prenatal cardiology consultation, 15 after a follow-up prenatal visit, and 20 after birth. Applied thematic analysis approach was used to code and analyse transcribed interviews. Coding and codebook revisions occurred iteratively; intercoder reliability was >80%.Results:Patients included mothers (16 [59%]), fathers (8 [30%]), and other support persons (3 [11%]). Initial fetal diagnoses included a range of moderate to severe CHD. Prenatally, parents sought to maintain hope while understanding the diagnosis; planning for the future rather than focusing on day-to-day was more common if prognoses were better. Postnatally, with confirmation of prenatal diagnoses, parents’ sense of control expanded, and they desired more active engagement in clinical decision making.Conclusions:To enhance effective communication and support, understanding how parents conceptualise hope in relation to diagnosis and how that may evolve over time is critical. Expectant parents whose child has a significant risk of mortality may demonstrate hope by focusing on positivity. As prognostic uncertainty diminishes postpartum, the parental role on the team may shift, requiring clinicians to provide different support.
Emerging trends: Deep nets thrive on scale
Authors: Church Kenneth Ward 
Published: August 2022

AbstractDeep nets are becoming larger and larger in practice, with no respect for (non)-factors that ought to limit growth including the so-called curse of dimensionality (CoD). Donoho suggested that dimensionality can be a blessing as well as a curse. Current practice in industry is well ahead of theory, but there are some recent theoretical results from Weinan E’s group suggesting that errors may be independent of dimensions$d$. Current practice suggests an even stronger conjecture: deep nets are not merely immune to CoD, but actually, deep nets thrive on scale.
Dose–response relationship between dietary inflammatory index and diabetic kidney disease in US adults
Authors: Wang Yong-Jun , Du Yang , Chen Guo-Qiang , Cheng Zhen-Qian , Liu Xue-Mei , Lian Ying 
Published: August 2022

AbstractObjective:The impact of the dietary potential inflammatory effect on diabetic kidney disease (DKD) has not been adequately investigated. The present study aimed to explore the association between dietary inflammatory index (DII) and DKD in US adults.Design:This is a cross-sectional study.Setting:Data from the National Health and Nutrition Examination Survey (2007–2016) were used. DII was calculated from 24-h dietary recall interviews. DKD was defined as diabetes with albuminuria, impaired glomerular filtration rate or both. Logistic regression and restricted cubic spline models were adopted to evaluate the associations.Participants:Data from the National Health and Nutrition Examination Survey (2007–2016) were used, which can provide the information of participants.Results:Four thousand two-hundred and sixty-four participants were included in this study. The adjusted OR of DKD was 1·04 (95 % CI 0·81, 1·36) for quartile 2, 1·24 (95 % CI 0·97, 1·59) for quartile 3 and 1·64 (95 % CI 1·24, 2·17) for quartile 4, respectively, compared with the quartile 1 of DII. A linear dose–response pattern was observed between DII and DKD (Pnonlinearity= 0·73). In the stratified analyses, the OR for quartile 4 of DII were significant among adults with higher educational level (OR 1·83, 95 % CI 1·26, 2·66) and overweight or obese participants (OR 1·67, 95 % CI 1·23, 2·28), but not among the corresponding another subgroup. The interaction effects between DII and stratified factors on DKD were not statistically significant (allPvalues for interactions were >0·05).Conclusions:Our findings suggest that a pro-inflammatory diet, shown by a higher DII score, is associated with increased odd of DKD.
Size and characteristics of family caregiving for people with serious illness: A population-based survey
Authors: Van Goethem Vincent , Dierickx Sigrid , Deliens Luc , De Vleminck Aline , Lapeire Lore , Cohen Joachim 
Published: August 2022

AbstractObjectivesFamily caregivers play a vital role in care for people with serious illness. Reliable population-level information on family caregiving is scarce. We describe the socio-demographic and family caregiving characteristics and experiences of family caregivers of people with serious illness in the adult population.MethodWe performed a secondary analysis of the cross-sectional population-based 19th Social-Cultural Changes survey. A random sample of 2,581 Dutch-speaking people aged 18–95, living in Flanders or Brussels, were contacted for participation in the survey between March and July 2014 using a stratified two-step sample. Differences between groups are described using Pearson chi-square tests and analysis of variance.ResultsResponse rate was 58.7% (1,515/2,581). Over a 12-month period, 7.6% of respondents provided family care for someone with a serious illness (n = 114). They were most often aged 55–74 (36.0%), women (57.9%), worked full-time (42.3%); 31.8% provided at least 10 h of family care each week. Family caregivers of people with serious illness, compared with family caregivers of people with other conditions, provided more medical and nursing care (33.3% vs. 22.5%, p = 0.027), and experienced a higher burden of family caregiving (p = 0.038) but a similarly high meaningfulness of family caregiving.Significance of resultsA considerable part of the adult working population provides family care for someone with serious illness. While family caregiving for someone with serious illness shows similarities with family caregiving for people with other conditions in terms of caregiver characteristics and the impact of caregiving on work-life balance and the meaning derived from it, it is also associated with increased burden.
From immigration over redistributive attitudes to welfare spending. The moderating role of social program design
Authors: Röth Leonce , Spies Dennis , Schmidt-Catran Alexander 
Published: August 2022

AbstractWhereas individual-level studies find that encompassing welfare states might in general be incompatible with large-scale immigration, studies on welfare spending find inconclusive results. We address this puzzle by pointing to the moderating role of social program design. We separate programs according to their degree of natives’ interest based on coverage, generosity and stratification characteristics for the social areas of unemployment, sickness/disability, and pensions for 18 OECD countries. We then test the moderating effect of natives’ interest on the impact of immigration on individual support for social spending and actual social spending in the three areas. Our results indicate that programs do react to immigration by decreasing support and budgets when natives’ interest is low, whereas programs where the interest of natives is high tend to increase individual support and spending.
Relations of Enhanced High‐Latitude Concurrent Blockings With Recent Warm Arctic‐Cold Continent Patterns
Authors: Zhao Liang , Dong Wei , Dong Xuefeng , Nie Suping , Shen Xinyong , Xiao Ziniu 
Published: August 2022

AbstractA warm Arctic‐cold continent (WACC) pattern has been one of the main characteristics of the Northern Hemisphere (NH) climate variability in winter during the last two decades. However, the factors contributing this pattern remain unclear. We compared the two leading modes of surface temperature in the NH winter on an interdecadal timescale and explored the role of high‐latitude concurrent blockings (HCBs) and the Arctic oscillation (AO) in these two modes. Results show that the first mode resembling the WACC pattern is more related to enhanced HCBs over the Ural Mountains and the North Pacific than the AO. The HCBs induce a warmer Arctic by simultaneously transporting large amounts of moisture and heat. The HCBs excite a tropospheric anticyclonic anomaly near the Arctic Circle, which, in turn, triggers anomalies in the propagation of planetary waves and the meridional circulation, with a subsequent redistribution of momentum and heat. This is accompanied by a weak polar night jet and a poleward shift in the subtropical westerly jet, resulting in mild cold mid‐latitude continents. The second mode represents the AO pattern, which has a different mechanism from WACC. The high‐pressure anomaly over the North Pacific has played an increasingly important part in the WACC mode in recent decades and the WACC pattern with HCBs is more easily reproduced in simulations with human activity. HCBs therefore require further consideration under the current and future conditions of global warming.
Particle‐Phase Uptake and Chemistry of Highly Oxygenated Organic Molecules (HOMs) From α‐Pinene OH Oxidation
Authors: Poulain L. , Tilgner A. , Brüggemann M. , Mettke P. , He L. , Anders J. , Böge O. , Mutzel A. , Herrmann H. 
Published: August 2022

AbstractSecondary organic aerosol (SOA) forms a major part of the tropospheric submicron particle mass. Still, the exact formation mechanisms of SOA have remained elusive. It is now admitted that highly oxygenated organic molecules (HOMs) can contribute to a large fraction of SOA formation. In this study, we performed a set of chamber experiments to investigate the SOA formation, and the HOMs uptake and processing directly formed by OH‐radical initiated oxidation of α‐pinene under two different aerosol seed conditions. Numerous HOM compounds were identified using advanced online and offline analytical techniques, and grouped into four classes according to their different uptake behaviors. For the first time, individual HOMs uptake coefficients ranging from 1.1 × 10−2 to 1.5 × 10−1 were experimentally determined and analyzed using a resistance model which considers uptake limitations by individual gas‐ and/or particle‐phase processes. This study demonstrates that the uptake coefficients of HOMs strongly depend on their molar mass and their respective O/C ratio. Results show that aerosol seed composition and phase state affect the initial uptake of HOMs. Furthermore, the study demonstrates that the acidity and/or different seed phase‐state can significantly enhance the subsequent uptake through occurring acidity‐driven reactions reflected in a reactive behavior, particularly under (NH4)HSO4 seed conditions, promoting up to 3 times a higher SOA mass formation including the formation of highly oxidized organosulfates (HOOS). Overall, the present study implies that HOMs and their subsequent chemical processing can play an important role in both the early growth of newly formed particles and SOA formation when particle acidity is high.