bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ophthalmic artery Doppler in the complementary diagnosis of preeclampsia: a systematic review and meta-analysis
Authors: Melo Pollyanna F.M. Vaz , Roever Leonardo , Mendonça Tânia M. S. , Costa Fabrício Silva , Rolnik Daniel Lorber , Diniz Angélica L. D. 
Published: June 2022

Abstract
Objective: To evaluate the accuracy of different parameters of the ophthalmic artery Doppler (OAD) in the complementary diagnosis of preeclampsia (PE).Methods: To investigate the mean difference in OAD values, peak systolic velocity (PSV), end-diastolic velocity (EDV), second systolic velocity peak (P2), resistance index (RI), pulsatility index (PI), and peak ratio (PR), between PE cases (overall and according to severity) and controls, random-effects meta-analyses were conducted for each Doppler parameter, with overall PE, mild and severe PE subgroups. Diagnostic performance and heterogeneity were evaluated with summary receiver-operating characteristics curves (sROC) and 95% confidence regions, obtained with bivariate modelsResults: Eight studies stratified the results in mild and severe or late and early PE, involving 1,425 pregnant women. PR and P2 had better diagnostic performance than the other indexes, with the PR of AUsROC at 0.885, the sensitivity of 84%, and specificity of 92%, with a low false-positive rate of 0.08 and the P2 with AUsROC of 0.926, the sensitivity of 85% and specificity of 88%. RI, PI, and EDV showed good performance and consistency across studies, but lower AUsROC of 0.833, 0.794, and 0.772, respectively.Conclusion: Ophthalmic artery Doppler is a complementary tool with good performance for diagnosis of overall and severe preeclampsia, with high and best sensitivity and specificity when using PR and P2 parameters.
An evidence-based approach towards identifying household emerging pollutants in rural areas in Southern Karnataka
Authors: Rathnamala G. V. , Shivashankara G. P. 
Published: June 2022

Abstract
The need for establishing the emerging pollutants for various rural households has witnessed a paradigm-shift towards health-related issues. Low-income groups have inadvertently contributed to environmental degradation due to improper hygienic conditions. In this paper, statistical analysis on gathered data from regional households in Karnataka has been evaluated for the health status of the individuals. A selected area based on village patterns was presented with a sample questionnaire in order to gather the patterns of household conditions prevailing in the area. A broad categorization based on the Fuzzy C clustering approach has classifiers in the form of demographic and socio-economic responses, water supply factors, sanitation, indoor air pollution, and solid waste management approaches. For each of the categories, the emerging pollutant has been identified which collectively points to ‘Poverty’ being the primary cause of deteriorating household conditions among people in such rural areas. The results of the questionnaire indicated a strong correlation between the prevalence of pollution and ill health in the low-income category of people. The authors opine that this investigation would contribute to the Government initiative of the Swachh Bharat Mission.
Study on Single-molecule Biophysics and Biochemistry in Dilute Liquids and Live Cells without Immobilization or Significant Hydrodynamic Flow: The Thermodynamic Single-molecule Demon
Authors: Foldes-Papp Zeno , Baumann Gerd 
Published: June 2022

Abstract:Since mathematics provides a way to answer questions about the thermodynamic jitter in a clear, rational manner, with evidence to support it, mathematics is the reliable method necessary to get the best information on the movement of a single molecule / a single particle at the molecular scale in dilute liquids and live cells without immobilization or hydrodynamic flow. The Brownian movement (normal diffusive systems) and generally the thermodynamic jitter (anomalous diffusive systems) are ultimately the direct or indirect cause of every measurement signal at the molecular scale in diffraction limited and unlimited optical systems in dilute liquids and live cells without immobilization or hydrodynamic flow. For example, emitted photons are the epiphenomenon of the underlying process of thermodynamic jitter of single molecules / single particles at the molecular scale. The key question is: How far apart do two molecules / two particles have to be in the time domain so that the required degree of separation between the two individual molecules / the two individual particles can be quantified at the molecular scale in order to distinguish them as separate entities without immobilization or hydrodynamic flow? The Földes-Papp’s limits of the singlemolecule time resolution in dilute liquids and live cells without immobilization or hydrodynamic flow are the exact answers. The diffusive process is complicated and not minimalist. A minimalist model has a third possibility, it may be right but irrelevant.
Clinical Evidence for the Effectiveness of Herbal Medicines in the Treatment
of an Obsessive- Compulsive Disorder: A Review Study
Authors: Abrishami Maryam Hosseini , Noras Mohamad Reza , Soltanifar Atefeh , Salari Roshanak , Jarahi Lida , Pazhouh Hamideh Khorram 
Published: June 2022

Background:
Obsessive-compulsive disorder (OCD) is a potentially debilitating disease
that affects 1-4% of the general population. It is characterized by the presence of obsessions and compulsions
which interfere with the individual’s life and functioning. Although conventional treatments
such as drug therapies and cognitive behavioral therapy exist for OCD, these treatments are not universally
successful and can cause side effects, which has created a demand for alternative and complementary
therapies.

Methods:
In this review, we summarize randomized clinical trials on the effectiveness of herbal medicines
for the treatment of OCD, and review the possible mechanisms of action for these medicines. A
search in PubMed, Scopus, and The Cochrane Library found 1022 studies, of which 7 were included
in our review.

Results:
The studies that we found were conducted over 6 to 12 weeks, and had an average sample
size of 37. The plant species studied included Crocus sativus, Echium amoenum, Hypericum perforatum,
Silybum marianum, Valeriana officinalis, and Withania somnifera. The trials demonstrated the
effectiveness of all plants as treatments for OCD except H. perforatum. The phytochemicals found in
these plants produce their effects through a variety of means such as inhibiting the reuptake of monoamines,
GABAergic effects, and neuroendocrine modulation. The small number of studies and their
small sample sizes, poor methodology, and lack of replication highlight the need for further research
into herbal medicines for the treatment of OCD.

Conclusion:
Overall, herbal medicines can be used as stand-alone therapies for OCD or in conjunction
with other methods.
Identification of Potent Bioactive Molecules Against NMDA Receptor and
Tau Protein by Molecular Docking Approach
Authors: Parvatikar Prachi , Bagali Shrilaxmi , Hippargi Surekha , Singh Pankaj K. , Singh Shashi Bala , Biradar M.S. , Patil Aravind V. , Das Kusal K. 
Published: June 2022

Introduction:
N-methyl-d-aspartate receptor (NMDAR) and tau protein play an important role
in neuronal death due to cerebral ischemia or ischemic stroke. Unfortunately, no drug has been discovered
except tissue plasminogen activator (tPA) to fight against ischemic stroke. Virtual high throughput
screening to find out possibilities of bioactive molecules to target NMDAR and tau protein to treat ischemic
stroke may be an option for drug discovery.

Objective:
The current study aimed to assess the molecular interaction of some bioactive molecules with
NMDAR and tau protein in silico to incriminate ischemic stroke.

Methods:
A computational method based on ligand-protein interaction technique has been used in the
present study to identify the therapeutic potential of some bioactive molecules for the possible treatment
of ischemic stroke. For this purpose, 50 bioactive molecules were screened and docking analysis was
performed for two target proteins, NMDAR and tau protein. In this study, for each protein target, the best
poses were identified based on binding energy and inhibition constant. Different pharmacological properties
of selected bioactive molecules were also analyzed to determine their absorption, distribution, metabolism,
excretion and toxicity (ADME/T) properties in silico. All were found in the acceptable range and
followed Lipinski’s rule.

Results:
In the present study of the 50 screened bioactive molecules, top 10 molecules have been identified,
of which best two bioactive molecules such as gossypin, viniferin have been predicted to be potential
neuroprotective agents against cerebral ischemia induced alteration of NMDAR and tau protein functional
integrities.

Conclusion:
Gossypin’ was the best bioactive compound interacting with NMDAR and tau protein.
“Make America White Again”. Los cambios en la política migratoria de Estados Unidos bajo el gobierno de Donald Trump
Authors: Cárdenas Alaminos Nuty 
Published: June 2022

El presente artículo analiza cómo uno de los cambios más importantes en el gobierno de Donald Trump fue la restricción del ingreso por la vía familiar en todas las dimensiones de la política migratoria: permanente, temporal, sin documentos y humanitaria. Basado en el modelo de Fitzgerald y Cook-Martin (2014), la selección de la población migrante se llevó a cabo a través de la aplicación de diversas órdenes ejecutivas y cambios administrativos. Específicamente, se elevaron los costos (económicos y humanitarios) para los migrantes y sus familias con la finalidad de desincentivarles a continuar con su proyecto migratorio (llegada, estadía y/o para la eventual reunificación de más familiares) según fuese el caso. Lo anterior en aras de cumplir uno de los idearios de dicha administración que fue detener el crecimiento de la población no blanca en Estados Unidos. La aplicación de esta política tuvo un particular impacto negativo en los mexicanos y centroamericanos.
Entre la igualdad y el binarismo. Una aproximación mexicana al uso de uniformes escolares
Authors: Vázquez-Parra José Carlos , Coss y León Coss y León Domingo 
Published: June 2022

El origen de los uniformes escolares tiene claras influencias religiosas, y su primordial motivación histórica era la adopción de valores como la humildad y el reducir cualquier tipo de desigualdad. Conforme han avanzado los siglos, el objetivo mismo de su uso puede llegar a ser cuestionado ante la presencia de estudiantes con una identidad de género diversa, pues terminan siendo un factor de segregación e invisibilización. La problemática social que implica la perpetuación del binarismo de género en los uniformes escolares, trae consigo no solo la negativa de representación de este colectivo de estudiantes, sino también un retroceso en el deseo de las instituciones educativas de ser cada vez más inclusivas y diversas. Por lo anterior, el presente ensayo crítico hace una reflexión basada en un análisis histórico-sociológico a partir de un recorrido cronológico en torno a la necesidad de abolir el género como elemento diferenciador de los uniformes escolares, partiendo desde la hipótesis de que esto es contrario a la razón originaria de estas indumentarias. En conclusión, se plantea la necesidad de volver al sentido original de estas prendas, como herramientas escolares promotoras de la igualdad, considerando la diversidad que se vive en los espacios educativos contemporáneos.
Pengetahuan Dan Persepsi Masyarakat Terhadap Konflik Gajah Sumatera Di Desa Lubuk Mandarsah
Authors: Bahari Ginda , Syarifuddin Hutwan , Hamzah Hamzah 
Published: June 2022

Kondisi Taman Nasionnal Bukit Tigapuluh yang berbatasan langsung dengan lahan pertanian dan pemukiman masyarakat Desa Lubuk Mandarsah serta adanya perizinan konsesi menyebabkan tingginya potensi konflik gajah sumatera dengan masyarakat. Penurunan keanekaragaman hayati akibat eksploitasi sumber daya alam yang berlebihan, konversi lahan perusahaan sekitar Taman Nasional Bukit Tigapuluh menimbulkan dampak negatif terhadap konservasi gajah sumatera dan keberlangsungan hidup masyarakat yang hidup disekitar daerah penyangga Taman Nasional Bukit Tigapuluh. Dengan adanya permaslaahan ini tentu akan menimbulkan konflik antara manusia dan gajah sumatera. Adapun tujuan dari penelitian ini adalah mengetahui pengetahuan dan persepsi dari masyarakat terhadap konflik dengan gajah sumatera. Penelitian ini merupakan penelitian menggunakan metode campuran atan mix method dimana mengkombinasikan metode Kualitatif dan kuantitatif. Dari penelitian ini dihasilkan bahwa Tingkat Pengetahuan Masyarakat di dusun Desa Lubuk Mandarsah terkait Gajah Sumatera sudah tergolong Tinggi (39-48) dengan persentase sebesar 82 % dan persepsi masyarakat di Desa Lubuk Mandarsah terkait gajah sumatera masik tergolong tidak baik dengan persentase 78%.
A Novel Intron-Encoded Neuropilin-1 Isoform in Pancreatic Islets Associated With Very Young Age of Onset of Type 1 Diabetes
Authors: MacDonald Michael J. , Ansari Israr-ul H. , Riedemann Amy S. , Stoker Scott W. , Eickhoff Jens C. , Chlebeck Peter J. , Fernandez Luis A. , Longacre Melissa J. 
Published: June 2022

<p> </p>
<p>Net synthesis of pancreatic beta cells peaks before two years of life. Beta cell mass is set within the first five years of life. Inframe translational readthrough of the <em>NRP1</em> gene exon 9 into intron 9 generates a truncated neuropilin-1 protein lacking downstream sequence necessary for binding VEGF that stimulates beta cell replication. VEGF is critical for developing but not adult islet neogenesis. Herein we show that cells in human pancreatic islets containing the full length neuropilin-1 possess insulin, but cells that contain the truncated neuropilin-1 are devoid of insulin. Decreased insulin cells increases susceptibility to onset of type 1 diabetes at a younger age. We also show that a genetic marker in <em>NRP1</em> intron 9 is higher in patients with onset of type 1 diabetes before age 4 years (31.8%), including 0.67-2 and 2-4 years, compared with onset at 4-8 years, 8-12 years, and after 16 years (16.1%) that equals its frequency in nondiabetic subjects (16.0%). Decreased insulin cells plus the genetic data are consistent with a low effect mechanism that alters the onset of type 1 diabetes to a very young age in some patients thus supporting the endotype concept that type 1 diabetes is a heterogeneous disease. </p>
Rodzaje standardów raportowania niefinansowego w przedsiębiorstwach
Authors: Majewska Iwona 
Published: June 2022

W artykule omówiono problematykę standaryzacji raportowania niefinansowego. Zwrócono uwagę na obowiązujące wytyczne w tym zakresie, w szczególności kto i co powinien raportować. Przedstawiono charakterystykę wybranych standardów raportowania niefinansowego. Została dokonana także analizą raportów niefinansowych 20 wybranych przedsiębiorstw w latach 2019-2021. Analiza ta została przeprowadzona pod kątem wykorzystywania dostępnych standardów przez przedsiębiorstwa.
Penerapan Aplikasi INLISLite di Perpustakaan Al-Qalam Fakultas Kedokteran Universitas Alkhairaat Palu
Authors: Rifka Rahmadani  , Iskandar  , Andi Muhammad Dakhalan  
Published: June 2022

Artikel ini membahas tentang penerapaka aplikasi INLISLite di Perpustakaan Al-Qalam Fakultas Kedokteran Universitas Alkhairaat Palu. Penelitian bertujuan untuk mengetahui a) penerapan atau penggunaan INLISLite, b) peluang dan kendala apa saja yang dihadapi pustakawan dalam mengoperasionalkan INLISLite, dan c) kendala apa saja yang dihadapi pemustaka dalam mengakses koleksi aplikasi INLISLite di Perpustakaan Al-Qalam Fakultas Kedokteran Universitas Alkhairaat Palu. Penelitian ini menggunakan metode penelitian kualitatif dengan pendekatan deskriptif. Dalam penelitian ini penulis menggunakan teknik pengumpulan data yaitu teknik observasi, wawancara dan dokumentasi. Penulis akan mewancarai pustakawan dan pemustaka/mahasiswa dalam mengumpulkan data. Data yang diperoleh kemudian dianalisis dengan beberapa teknik yaitu, reduksi data, penyajian data dan verifikasi data. Untuk menguji keabsahan data yang diperoleh, penulis menggunakan teknik perpanjangan pengamatan dan triangulasi. Hasil penelitian menunjukkan bahwa penggunaan aplikasi INLISLite di Perpustakaan Al-Qalam Fakultas Kedokteran Universitas Alkhairaat Palu belum digunakan secara optimal oleh pustakawan dalam mengelola perpustakaan. Kendala yang dihadapi pustakawan dalam mengoperasikan aplikasi INLISLite adalah masih kurangnya pengetahuan pustakawan tentang aplikasi INLISLite dan kurangnya sumber daya manusia yang ahli dalam pengetahun TIK serta beberapa kendala pada server. Manfaat atau peluang yang didapatkan dalam menggunakan apliaksi INLISLite ini sangat mengefisienkan waktu apa lagi dalam penginputan data koleksi kedalam INLISLite untuk dijadikan koleksi digital. Penggunaan OPAC masih kurang dimanfaatkan pemustaka untuk mencari koleksi bahan pustaka, kerena banyak koleksi yang tidak sesuai yang tampil di OPAC dengan di rak buku.
A flexible endotracheal tube introducer improves first-attempt success of intubation in cats by novice anesthetists
Authors: Martin-Flores Manuel , Sakai Daniel M. , Muto Richard Marra , Burns Charlotte C. , Araos Joaquin D. , de Miguel Garcia Cristina , Campoy Luis 
Published: June 2022

Abstract

OBJECTIVE
To test whether the use of a flexible endotracheal tube introducer (ETI) facilitates intubation of cats by veterinary students with little or no experience.

ANIMALS
125 healthy cats.

PROCEDURES
Cats were sedated with dexmedetomidine and morphine IM, and anesthesia was induced with propofol. They were randomly assigned to be intubated by supervised veterinary students using an ETI within a tracheal tube or an endotracheal tube alone (3.0, 3.5, or 4.0 internal diameter sizes). Success rate at first attempt, number of attempts to intubate (up to 3), and time to intubate were recorded. Multivariate logistic regression was used to test associations between several factors such as use of an ETI, cat’s weight, endotracheal tube size, administration of ketamine for sedation, and first-attempt success. Significance was considered when P < 0.05.

RESULTS
Success rate for the first attempt was higher with an ETI (79% [51/64) than without it (46% [28/61]), and attempts to intubate were fewer when an ETI was used (both P < 0.001). Time to intubate did not differ between groups (ETI, 30 seconds [4 to 143 seconds]; endotracheal tube, 28 seconds [5 to 180 seconds]). Use of an ETI was positively associated with improved first-attempt success, and the 3.0-mm internal diameter of the tube was negatively associated (both P ≤ 0.001).

CLINICAL RELEVANCE
The use of a flexible ETI improved the success of first-attempt intubation of cats by veterinary students. This technique may help minimize the number of attempts during intubation and incidence of complications that could arise from multiple attempts.
Potret Kemiskinan sebagai Ide Penciptaan Seni Lukis
Authors: Eddy Fananantsoa Jean 
Published: June 2022

Abstrak
Hidup itu seperti hitam dan putih. Di antara dua warna itu, ada banyak hal yang kita lihat dan rasakan dalam kehidupan sehari-hari seperti kebahagiaan, kesedihan, kemarahan, dan lain-lain. Kita semua memiliki banyak pengalaman dalam kehidupan kita dari apa yang kita lakukan, lihat, dengar, rasakan, cium, dan lain-lain. Kemiskinan bukanlah pilihan dan tidak ada yang terlahir untuk menjadi miskin tetapi ada beberapa orang yang masih sulit kehidupanya. Pertanyaannya adalah: “Apakah mereka memilih menjadi miskin? Apakah mereka melanggarnya? Apakah ini kutukan? Atau apakah itu hasil dari kemalasan?” Artikel jurnal yang berjudul “Ekspresi Kemiskinan sebagai Ide Penciptaan Seni Lukis” ini adalah untuk menunjukkan dalam karya seni visual apa itu ekspresi kemiskinan melalui perasaan sendiri. Bagi penulis juga sangat penting untuk menunjukkan bahwa tidak hanya sisi negatif dari kemiskinan yang ditampilkan tetapi juga sisi positif karena semua orang memiliki hak yang sama seperti bahagia, bercanda, bermimpi, dan lain-lain. Pesan sederhana penulis adalah bahwa kita semuanya manusia, mari kita
hentikan diskriminasi, jangan hanya mengawasi mereka, mari semua
mendidik jiwa, pikiran dan hati kita untuk saling menjaga satu sama lain. Kita semua manusia.

Abstract
Life is like black and white. Between those two colors, there are many things that we see and feel in our everyday life such happiness, sadness, anger etc. We all have many experiences in our lives from what we do, see, hear, feel, smell, etc. The poverty is not a choice and no one was born to be poor but there are some people who are still in difficulties. The question is that : “Did they choose it? Do they diserve it? Is it a curse? Or is it the result of laziness? My Final Project’s title “Expression of Poverty as an idea of creating the painting Art work” in order to show what is expression of poverty through the feeling. And it is very important also to show two sides which are negative and positive in the Art works because all people have the same right like to be happy, to joke, to dream, etc. Thet simple message is that we all are humans, let’s stop discrimination, let’s not just watch them, let’s educate our souls, minds and hearts in order to take care of each other. We are all humans.
Guna dan Fungsi Tari Bedana bagi Masyarakat Etnis Arab Melayu Jambi
Authors: Sy Hasnah Sy, , M Hartati , Riswani Riswani 
Published: June 2022

Abstrak
Etnik Arab Melayu merupakan salah satu sub-etnik Melayu Jambi.
Mayoritas mereka bermukim di Desa Seberang yang berseberangan dengan Angso Duo Kota Jambi. Bedana berupa tarian dengan iringan ansambel musik gambus berkhas Arabic telah diwarisi secara turun-temurun dari leluhur mereka. Tulisan ini mengkaji aspek guna dan fungsi tari Bedana yang telah fungsional untuk memeriahkan dan memberi suasana hiburan bagi pelaksanaan berbagai upacara berciri khas budaya Islami yang dimiliki masyarakat etnis Arab Melayu Jambi tersebut, sehingga tari Bedana menjadi identitas etnik Arab Melayu di tengah-tengah masyarakat etnis lain di Kota Jambi. Capaian tulisan ini berupa deskripsi kualitatif pada aspek guna tari Bedana sebagai pemeriah helat, hiburan, dan menjadi wadah komunikasi dalam sebuah interaksi sosial mereka. Pada sisi fungsi, tari ini berhubungan dengan aspek status sosial ekonomi masyarakat pendukung, identitas budaya, masalah keberlanjutan status budaya, dan sebagai penguat sosial budaya etnis Arab Melayu di Jambi.

Abstract
Ethnic of Malay Arab represent one of the Malay sub-ethnic of Jambi. Their Majority live in countryside defect which is beside with Angso Duo of Jambi Town. Bedana in the form of dance with music ensemble accompaniment of gambus typical of Arabic have inherit hereditaryly from their ancestor. This article study aspect use and function of Bedana dance which have functional to enliven and give entertainment amusement atmosphere to execution various ceremony have cultural special of Islami had by ethnical society of Arab Malay of Jambi, that Bedana dance become ethnic identity of medial Arab Malay of other ethnical society in Town of Jambi. This Performance Article in the form of descriptions qualitative at aspect utilize dance of Bedana as ceremonial of party, entertainment, and become the place of communications in a social interaction of them. At function side, this dance relate to social status aspect of supporter society economics, cultural identity, problem continue cultural status, and as social of ethnical culture of Arab Malay in Jambi.