bluuebunny/crossref_metadata_2025_split huggingface dataset:
How and Where the Birth Delivery Taking Place Matter towards the Success of Exclusive Breastfeeding
Authors: Roseprilla Adamina Dinda , Mahmudiono Trias , Rachmah Qonita 
Published: November 2022

Background: Breast milk is the best nutrition for babies. The coverage of exclusive breastfeeding in Indonesia in 2017 was still low. However, there are many factors that contribute to low rates of exclusive breastfeeding including socio-cultural factors, factors related to the health system, market, environment, and knowledge. Recent studies have shown that there was a relationship between the place and type of delivery with exclusive breastfeeding. Objectives: This study aimed to analyze the correlation between the place and type of delivery with the success of exclusive breastfeeding practice in Indonesia among mothers of infants 0-6 months.Methods: This study was a secondary data analysis using data from the results of the 2017 Indonesia Demographic and Health Survey (IDHS), conducted in 34 provinces in Indonesia with a total sample of 1810 infants aged 0-6 months. The dependent variable was the exclusive breastfeeding. Independent variables were mother’s age, mother’s level of education, parity, place of delivery, and type of delivery. Data collection was carried out for all variables by interviewing using a reproductive woman questionnaire. Data were analyzed using chi square test.Results: The results showed that 48.2% of mothers gave exclusive breastfeeding. The results of the bivariate analysis showed that the variables of place of delivery (p-value=0.045), type of delivery (p-value<0.001), and mother’s age (p-value=0.048) were related to the practice of exclusive breastfeeding.Conclusions: The conclusion of this study was the factors that affecting exclusive breastfeeding in were place of delivery, type of delivery, and mother’s age.Keywords: exclusive breastfeeding, place of delivery, type of delivery, early life nutrition
A Millennial-Scale Tephra Event-Stratigraphic Record of the South China Sea since the Penultimate Interglacial
Authors: Feng Weijia , Yang Jiawen , Bao Chuang , Kong Deming , Chen Min-Te 
Published: November 2022

Abstract
Large volcanic eruptions have significant impacts on climate and environmental changes. The deposition of tephra in marine sediments may serve as an eruption recorder, but it has not been extensively studied in the western Pacific. This study explored a millennial-scale tephra event-stratigraphy with multiple indicators in a sediment core collected from the eastern South China Sea (SCS) basin. The magnetic susceptibility (MS), Fe and Mn concentrations determined by X-ray fluorescence (XRF), and identification of individual ash particles were used to identify tephra layers and reconstruct the history of volcanic activity. Nine visible volcaniclastic units (VVU) and two cryptotephra layers have been identified based on their distinct features, as manifested by high MS, Fe, and Mn concentrations and single-peak grain size distribution. The VVUs and cryptotephra layers reveal elevated volcanic activities. Using the radiocarbon age model and oxygen isotope stratigraphy, these episodes could roughly correspond to the following periods: 1-11 ka, 16-17 ka, 27-31 ka, 41-42 ka, 45-46 ka, 49-50 ka, 77-80 ka, 90-91 ka, 97-99 ka, 116-126 ka, and 132-140 ka. The alkenone-derived SST has significant glacial cycles and good synchronicity with other SCS SST records, which could partially help build the preliminary age model. Despite possible age errors larger than 1 kyr, the discovery and timing of tephra layers provide a preliminary framework to further investigate the impact of historical volcanic eruptions on climate changes.
Flow Assurance Management in Geothermal Production Wells
Authors: Matoorian Raya , Malaieri Mohammadreza 
Published: November 2022

Abstract
Flow assurance ensures that geothermal fluids (hot water and steam) flow properly in a pipe or well and are transferred to a power plant safely and cost-effectively. Inorganic deposition (scales) is regarded as the primary issue in geothermal fluid flow, and a reliable controlling strategy to predict and prevent scaling is essential.
We introduced a practical scale integrity management strategy to predict and prevent scaling in the flowline to achieve this goal. Thermochemical modeling is the primary predictive model to predict why, where, and when scaling will occur. Then two treatment approaches (chemical and non-chemical) are investigated to prevent and treat scaling. What-if analysis is extensively applied to propose an economic plan.
Due to the inability of laboratory research to replicate the extreme pressures and temperatures of geothermal wells, experts do not know precisely when and how minerals dissolve down in the well and are unable to offer regulating recommendations. Therefore, an efficient scale integrity management plan must be implemented. Simulation tools play a significant part in the development of flow assurance, as they provide a consistent framework for testing various what-if scenarios and aid in making the best operational solution. Injecting chemicals is not always economical to control scaling in geothermal operation due to the cost and inefficiency in high-pressure and high-temperature situations in these wells, and the non-chemical approach should be prioritized. Potential non-chemical approaches include sulfate reduction, operating wells outside critical scaling envelopes, reinjecting produced water, and lifting gas injection with more CO2.
This research intends to broaden the flow assurance concept in geothermal wells by analyzing the impediments and treatments from wells to the surface facilities.
Automation of Calculation and Management for HPHT Well Operating Limits - WIMS Coupled Engineering Analysis Approach
Authors: Al Sawadi Obadah - 
Published: November 2022

Abstract
The objective of this paper is to demonstrate and discuss the implementation of an automated workflow that calculates and manages the Operating Limits of Oil and Gas wells, particularly HPHT.
The workflow is primarily based on representative well data and equipment inventory. It runs reliable engineering calculations (including tubular triaxial stress and sensitivity analyses) to define the well operating envelopes. It is aimed to 1) maximize the operating envelopes of well tubulars and downhole packers -compared to other conventional methods- and 2) prevent costly failures of critical well barrier elements (WBE).
Results of this automation were encouraging. 100s of SME time hours are saved. Reliable and consistent analysis are performed for MAASP/MAWOP and overall well Operating Envelopes. Millions of dollars are saved by preventing potential and costly unnoticed tubular and/or downhole packer failures that could have been prevented. HSE/ESG is better served. Furthermore, this paper initiates a discussion to review implementation and compare feasibility industry applied methods that calculate wells’ operating envelopes.
Important Note: All well data, engineering analysis, operating limits and well information etc., displayed or referred to in this publication, are not necessarily actual and only used for illustration purposes.
Neuroanatomical predictors of real-time fMRI-based anterior insula regulation. A supervised machine learning study.
Authors: Caria Andrea , Grecucci Alessandro 
Published: November 2022

Abstract
Increasing evidence showed that learned control of metabolic activity in selected brain regions can support emotion regulation. Notably, a number of studies demonstrated that neurofeedback-based regulation of fMRI activity in several emotion-related areas leads to modifications of emotional behavior along with changes of neural activity in local and distributed networks, in both healthy individuals and individuals with emotional disorders. However, the current understanding of the neural mechanisms underlying self-regulation of the emotional brain, as well as their relationship with other emotion regulation strategies, is still limited. In this study, we attempted to delineate neuroanatomical regions mediating real-time fMRI-based emotion regulation by exploring whole brain GM and WM features predictive of self-regulation of anterior insula (AI) activity, a neuromodulation procedure that can successfully support emotional brain regulation in healthy individuals and patients. To this aim, we employed a multivariate kernel ridge regression model to assess brain volumetric features, at regional and network level, predictive of real-time fMRI-based AI regulation. Our results showed that several GM regions including fronto-occipital and medial temporal areas and the basal ganglia as well as WM regions including the fronto-occipital fasciculus, tapetum and fornix significantly predicted learned AI regulation. Remarkably, we observed a substantial contribution of the cerebellum in relation to both the most effective regulation run and average neurofeedback performance. Overall, our findings highlighted specific neurostructural features contributing to individual differences of AI-guided emotion regulation. Notably, such neuroanatomical topography partially overlaps with the neurofunctional network associated with cognitive emotion regulation strategies, suggesting common neural mechanisms.
The constituents of trust in the context of a return to work following a work disability: A scoping review protocol
Authors: Tamokoue Hermann Brice Tegninko , Gouin Marie-Michelle 
Published: November 2022

Abstract
Background: Long-term work disability due to a musculoskeletal disorder (MSK) or a common mental disorder (CMD) is a serious issue that affects the whole of society. Facilitating relationships between the multiple stakeholders involved in someone’s return to work (RTW) has emerged as a key avenue for a successful RTW and must include building trust between stakeholders. Although the constituents of trust have been identified in previous social science and business studies, no review has yet documented which have been explored in the context of RTW.
Methods: We will conduct a scoping review using Peters and coll.’s methodology and the PRISMA-P methodology to identify the constituents of trust that have been explored in the context of RTW following a work disability due to a MSK or a CMD. Full-text studies in English and French will be retrieved from the following databases: PsycINFO, CINAHL, ABI/INFORM, Business Source Complete, Scopus, and PubMed. The authors will extract, chart, categorize and summarize the data in the papers selected.
Discussion: The results will be used to develop a tool for building trust between RTW stakeholders. More specifically, the operationalization of trust will be discussed in an expert consensus group on how to build trust between stakeholders and in turn facilitate the RTW.
Systematic review registration: PROSPERO does not register scoping reviews.
Real-World Data on the Incidence and Risk of Guillain-Barre Syndrome Following SARS-CoV-2 Vaccination: A Prospective Surveillance Study
Authors: Ha Jongmok , Park Suyeon , Kang Hyunwook , Kyung Taeeun , Kim Namoh , Kim Dong Kyu , Kim Hyeonjoon , Bae Kihoon , Song Min Cheol , Lee Kwang June , Lee Euiho , Hwang Beom Seuk , Youn Jinyoung , Seok Jin Myoung , Park Kunhee 
Published: November 2022

Abstract
Increasing evidence suggests an association between SARS-CoV-2 vaccines and Guillain-Barré syndrome (GBS). Nevertheless, little is understood about the contributing risk factors and clinical characteristics of GBS post SARS-CoV-2 vaccination. In this prospective surveillance study of 38,828,692 SARS-CoV-2 vaccine doses administered from February 2021 to March 2022 in the Gyeonggi Province, South Korea, 55 cases of GBS were reported post vaccination. We estimated the incidence rate of GBS per million doses and the incidence rate ratio for the vaccine dose, mechanism, age, and sex. Additionally, we compared the clinical characteristics of GBS following mRNA-based and viral vector-based vaccinations. The overall incidence of GBS following SARS-CoV-2 vaccination was 1.42 per million doses. Viral vector-based vaccines were associated with a higher risk of GBS. Men were more likely to develop GBS than women. The third dose of vaccine was associated with a lower risk of developing GBS. Classic sensorimotor and pure motor subtypes were the predominant clinical subtypes, and demyelinating type was the predominant electrodiagnostic subtype. The initial dose of viral-vector based vaccine and later doses of mRNA-based vaccine were associated with GBS, respectively. GBS following SARS-CoV-2 vaccination may not be clinically distinct. However, physicians should pay close attention to the classic presentation of GBS in men receiving an initial dose of viral vector-based SARS-CoV-2 vaccines.
Subcuticular suture and incisional surgical-site infection in elective hepatobiliary and pancreatic surgery: an open-label, pragmatic randomized clinical trial (CLOSKIN trial)
Authors: Aguirre-Allende Ignacio , Alkorta-Zuloaga Maialen , Iglesias-Gaspar Maria Teresa , Urreta-Ballobre Iratxe , García-Domínguez Amaia , Arteaga-Martin Xabier , Beguiristain-Gómez Adolfo , Medrano-Gómez Miguel Ángel , Ruiz-Montesinos Inmaculada , Riverola-Aso Ana Paula , Jiménez-Agüero Raúl , Enríquez-Navascués José María 
Published: November 2022

Abstract
Background: subcuticular suture has proven to reduce superficial incisional SSI (si-SSI) in clean surgery. However, question remains regarding clean-contaminated procedures. The aim of this study is to assess that subcuticular suture is superior to staples in reducing si-SSI incidence in elective HBP surgery.
Methods: single-centre, open-label, parallel, pragmatic randomized clinical trial conducted at a referral tertiary Hospital between January 2020 and April 2022. Patients eligible for elective HBP surgery were randomly assigned (1:1) to subcuticular suture or surgical staples wound closure using a minimisation method based on previously confirmed risk factors. The primary endpoint was the incidence of si-SSI. Considered secondary endpoints were major postoperative morbidity in both groups, additional wound complications, median hospital length of stay and need for re-hospitalisation.
Results: Of the 379 patients, 346 patients were randomly assigned to receive skin closure with staples (n= 173) or subcuticular suture (n= 173). After exclusion of 11 participants, 167 and 168 patients respectively in the control and the experimental group received their allocated intervention. For the primary endpoint, no significant differences in si-SSI rate were found: 17 (9.82%) staples group vs. 8 (4.62%) in subcuticular suture group (p= 0.062). Subset analysis confirmed absence of significant differences. As for secondary endpoints, overall wound complications did not differ significantly between two procedures: 19 (10.98%) vs. 10 (6.35%) (p= 0.127). There were no treatment related adverse events. However, occurrence of si-SSI contributed to major postoperative morbidity in both groups (p< 0.001 and p= 0.018) and to a substantially prolonged postoperative hospitalization (p= 0.015).
Conclusions: subcuticular suture might offer a relative benefit for skin closure reducing incidence of si-SSI after elective HBP surgery, although this was found not to be clinically relevant. Yet, this should not be interpreted as equivalence among both treatments. Therefore, wound closure strategy should not be based only on these grounds.
Trial registration number: ISRCTN Registry number ISRCTN37315612 (registration date: 14/01/2020)
Single cell RNA sequencing reveals C5aR1 inhibition to selectively target pro-tumorigenic M2 macrophages reversing PARP inhibitor resistance
Authors: Li Xi , Poire Alfonso , Jeong Kang Jin , Zhang Dong , Ozmen Tugba , Chen Gang , Sun Chaoyang , Mills Gordon 
Published: November 2022

Abstract

Although Poly (ADP-ribose) polymerase (PARP) inhibitors (PARPi) have been approved in multiple diseases, including BRCA1/2 mutant breast cancer, responses are usually transient thus requiring the deployment of combination therapies that can prevent or reverse PARPi resistance. We thus explored mechanisms underlying sensitivity and resistance to PARPi using two intrinsically sensitive and resistant syngeneic murine breast cancer models. Our data indicate that the PARPi-sensitive tumor model has a high ratio of M1 anti-tumor/M2 pro-tumor macrophages with the M1/M2 ratio being increased by PARPi. In contrast the PARPi-resistant tumor model had very low levels of M1 macrophages and thus a low M1/M2 ratio that was not altered by PARPi. Transplantation of the PARPi-sensitive and the PARPi-resistant tumor in opposite mammary fat pads results in accumulation of M2 macrophages in the sensitive tumor, rendering the sensitive tumor PARPi resistant suggesting that transit of M2 macrophages could contribute to resistance across distant sites both within and between tumors. C5ar1 and Rps19/C5ar1 signaling are selectively elevated in the M2 macrophages that are associated with PARPi resistance. Indeed, C5aR1 positive cells were sufficient to transfer resistance to PARPi. Strikingly targeting C5aR1 decreased M2 macrophage numbers, while sparing M1 macrophages rendering PARPi-resistant tumors sensitive to PARPi in a CD8 T cell dependent manner. Consistent with the murine data, high C5aR1 levels in human breast cancers are associated with a poor response to immune checkpoint blockade. Thus, targeting C5aR1 may represent an approach to selectively deplete M2 macrophages and engender sensitivity to PARPi and potentially other therapies.
Abscisic acid increases the viability of cryopreserved shoot tips of Lilium pumilum by regulating the osmotic stress and programmed cell death
Authors: Wang Qi , Zhu Mengting , Zhang Lingling , Liu Yan 
Published: November 2022

Abstract
Lilium pumilum plays an important role in lilium resistance breeding because of its wide distribution and strong stress resistance. It is of great significance to establish an efficient cryopreservation procedure for Lilium pumilum. In this study, the cryopreservation protocol of Lilium pumilum shoot tips by vitrification was established as follows: The 2 months old tissue-culture plants, which outer scales of small bulbs at the base of small plants were removed and only the 1–2 layers scales that encasing the shoot tips were retained were precultured on Murashige Skoog medium (MS) with 0.5M sucrose and 25µM abscisic acid(ABA) for 7 days at 4℃ in the dark; Then, the 2 mm shoot tips were gain under stereoscopic microscope in an ultra-clean workbench, and 10 shoot tips were put into a 1.5ml frozen centrifuge tube and added 1ml Loading solution (MS + 0.4M sucrose + 2M glycerin) for 20min at 25°C; then the Loading solution was removed, precooled PVS2 solution (MS + 0.4M sucrose + 30% glycerol + 15% ethylene glycol + 15%DMSO) was added for 80min at 0℃; The tube was plunged into liquid nitrogen and keeping. When it was needed, the tube was removed from the liquid nitrogen tank, and rapidly thawed in 37 ℃ water bath for 60s; After that, PVS2 solution was removed and shoot tips were washed twice for 10 min each time with unloading solution (MS + 1.2M sucrose) at 25 ℃. Subsequently, the shoot tips were incubated on medium (MS + 30 g·L− 1 sucrose + 6.5 g·L− 1 agar) for regeneration. With this procedure, the shoot tips survival rate was 93.64% and the recovery rate was 63.33%. Further biochemical studies showed that adding exogenous ABA increased the contents of endogenous osmotic regulatory substances (proline, soluble sugar, soluble protein) and reduced the activities of caspase-3-like and caspase-9-like enzyme that characterize programmed cell death (PCD). This suggests that the addition of ABA during preculture phase improved viability of shoot tips by affecting osmotic stress and PCD.
Irreversibility Analysis of Electromagnetic Hybrid Nanofluid Over a Stretchable Surface with Cattaneo-Christov Heat Flux Model: Finite Element Approach
Authors: Qureshi Muhammad Amer 
Published: November 2022

Abstract
To get a better heat transmission capacity of ordinary fluids, new hybrid nanofluids (HNFs) with a considerably greater exponent heat than nanofluids (NFs) are being used. HNFs, which have a greater heat exponent than NFs, are being applied to increase the HT capacities of regular fluids. Two-element nanoparticles mixed in a base fluid make up HNFs. This research investigates the flow and HT features of HNF across a slick surface. As a result, the geometric model is explained by employing symmetry. The technique includes nanoparticles shape factor, Magnetohydrodynamics (MHD), porous media, Cattaneo-Christov, and thermal radiative heat flux effects. The governing equations are numerically solved by consuming a method known as the Galerkin finite element method (FEM). In this study, H2O-water was utilized as an ironic, viscous improper fluid, and HNF was investigated. Copper (Cu) and Titanium Alloy (Ti6Al4V) nanoparticles are found in this fluid. The HT level of such a fluid (Ti6Al4V-Co/H2O) has steadily increased in comparison to ordinary Co-H2O NFs, which is a significant discovery from this work. The inclusion of nanoparticles aids in the stabilization of a nanofluid flowing and maintains the symmetry of the flow form. The thermal conductivity is highest in the boundary-lamina-shaped layer and lowest in sphere-shaped nanoparticles. A system's entropy increases by three characteristics: their ratio by fractional size, their radiated qualities, and their heat conductivity modifications.
Extended Chebyshev Wavelet of First Kind and its Applications in Approximation of a Function Belonging to Hölder’s Class and Solution of Fredholm Integral Equation of Second Kind
Authors: Lal Shyam , Yadav Harish Chandra 
Published: November 2022

Abstract
Note: Please see pdf for full abstract with equations.
In this paper, six approximations E(1)µk,0, E(1)µk,M, E(2)µk,0, E(2)µk,M,E(3)µk,0,E(3)µk,M of functions of classes H α[0, 1), H α,χ[0, 1), H ϕ[0, 1) by (µk, 0)th and (µk, M)th partial sums of their first kind extended Chebyshev wavelet expansion inthe interval [0, 1), for µ > 1, have been estimated. The solution of the Fredholm integral equation of the second kind by the first kind extendedChebyshev wavelets have been obtained. The solution obtained by extended Chebyshev wavelet of the first kind is approximately the same astheir exact solution. This is a significant achievement of this researchpaper in wavelet analysis.
Mathematics Subject Classification: 42C40, 45B05, 65T60, 65R20.