bluuebunny/crossref_metadata_2025_split huggingface dataset:
Keyakinan Hukum Karma Memoderasi Pengaruh Hedonisme Pada Kecurangan Dalam Pelaporan Keuangan
Authors: Megawati Anak Agung Tri 
Published: March 2022

This study aims to examine the effect of hedonism on fraudulent financial reporting and the belief in the law of karma as a moderating variable of the effect of hedonism on fraud. This type of research is quantitative. The research was conducted at the Village Credit Institution in Denpasar City using primary data obtained by distributing questionnaires. The method of determining the sample using the saturated method and obtained as many as 105 respondents. The data analysis technique used is the interaction test of the moderating variable Moderated Regression Analysis (MRA). Based on the results of the analysis, it shows that hedonism has a negative effect on fraudulent financial reporting. The results of the study indicate that high hedonism in an individual can reduce the occurrence of fraud in financial reporting. The belief in the law of karma moderates the effect of hedonism on fraud that the belief in the law of karma weakens the influence of hedonism on fraud in financial reporting.
Keywords: Hedonism; Belief in the Law of Karma; Financial Reporting Fraud.
Determinant Improving the Quality of Financial Reports Pematangsiantar City Government
Authors: Silitonga Hery Pandapotan , Sianipar Ruth Tridianty , Putri Juan Anastasia , Siregar Robert Tua , Sudirman Acai 
Published: March 2022

This study aims to determine the effectiveness of SPIP and organizational culture impact the successful implementation of SIKD in improving the quality of financial reports. A quantitative approach was used in this study with a literature and field design. The data sources used are primary data and secondary data. The data analysis technique used in this study was path analysis. The results showed that the t-test of the sub-structure model 1 of SPIP affected the success of SIKD implementation, organizational culture affected the success of the implementation of SIKD, and the t-test of the sub-structure model 2 showed that SPIP affected the quality of financial reports. organizational culture does not affect the quality of financial statements, and SIKD affects financial reports' quality. Furthermore, the effectiveness of the application of SIKD is an intermediary variable that affects the quality of financial reports in the Pematangsiantar City government.
Keywords : SPIP; Organizational Culture; SIKD; Financial Report Quality.
Kecerdasan Emosional, Perilaku Belajar, Kompetensi Dosen dan Tingkat Pemahaman Akuntansi
Authors: Lameng Alexandro Aditya Dewa Bharata , Damayanthi I Gst Ayu Eka 
Published: March 2022

The purpose of the study was to obtain empirical evidence regarding the influence of emotional intelligence, learning behavior, and lecturer competence on the level of accounting understanding. The study involved students majoring in accounting for the 2016-2017 undergraduate program, Faculty of Economics and Business, Udayana University. The number of samples taken as many as 117 student respondents using purposive sampling method. Data was collected by means of a questionnaire. The analysis technique used is multiple linear regression analysis technique. The results of this study indicate that learning behavior and lecturer competence have a positive and significant effect on the level of accounting understanding. While emotional intelligence has no effect on the level of understanding of accounting.
Keywords: Emotional Intelligence; Learning Behavior; Lecturer Competence; Accounting Understanding Level.
“This was not the time for this type of 1890 imperialism”: Cryolite, Control, and Canada-US Relations over Greenland, 1940
Authors: Smith Gordon W. , Lackenbauer P. Whitney 
Published: March 2022

This article is drawn from the unpublished second volume of Gordon Smith’s magnum opus, A Historical and Legal Study of Sovereignty in the Canadian North and Related Law of the Sea Problems. Edited and introduced by P. Whitney Lackenbauer, this article explores Canada-United States relations over Greenland in 1940, particularly whether Canada or the United States would secure de facto control over Greenland and its unique supply of cryolite, essential for the production of aluminum at that time. In doing so, Smith contributes to our understanding of how competing interests and priorities made Greenland a site of rivalry and ultimately compromise between Second World War allies.
Cet article est tiré du deuxième volume inédit du grand ouvrage de Gordon Smith, intitulé A Historical and Legal Study of Sovereignty in the Canadian North and Related Law of the Sea Problems. Édité et présenté par P. Whitney Lackenbauer, cet extrait traite des relations canado-américaines relatives au Groenland en 1940, en particulier du contrôle de fait éventuel par le Canada ou les États-Unis du Groenland et de son unique approvisionnement en cryolite, essentielle à la production d’aluminium à l’époque. Ainsi, Smith nous aide à mieux comprendre la façon dont les priorités et les intérêts divergents ont fait du Groenland un site de rivalité et, en fin de compte, de compromis entre les alliés de la Seconde Guerre mondiale.
Relationship between first-line treatment response and bone marrow fibrosis in newly diagnosed multiple myeloma
Authors: Halacoglu Aysun 
Published: March 2022

Objectives:
Multiple myeloma (MM) occurs with uncontrolled and clonal increase proliferation of plasma cells in the bone marrow. Myelofibrosis can be primary or can be secondary when associated with other malignant or non-malignant diseases. MM is a malignant disease in which both collagen and reticulin fibrosis can be detected together at the time of diagnosis.The aim of this study is to investigate the relationship between bone marrow fibrosis at diagnosis and response to after first-line treatment in newly diagnosed MM.

Material and Methods:
In this study, 95 newly diagnosed MM patients were analyzed retrospectively. Demographic characteristics, complete blood count, biochemical examinations, bone marrow fibrosis grades, and first-line treatment response of the patients were retrieved from records as it is a retrospective study. Patients were divided into 2 groups according to their response to first- line treatment. Patients who have a strict complete response (sCR), complete response (CR) or a very good partial response (VGPR) responses to first-line therapy were included in the first group. Patients who gave partial response (PR), minimal response (MR) or progressive disease (PD) responses to the first-line therapy were included in the second group.

Results:
There were 72 patients in the Group I (good response group) and 23 patients in Group II (poor response group). Between the good response group and poor response group myeloma type, platelet count at diagnosis, β2 microglobulin, lactate dehydrogenase, erythrocyte sedimentation rate, bone marrow plasma cell ratio, R-ISS, and first-line treatment were not statistically significant (P > 0.05 ). Age was statistically significantly lower in the good response group (P = 0.04). In male gender, a better response was obtained (P = 0.02). At the time of diagnosis, hemoglobin levels in the good response group were found high compared to the poor response group (P = 0.02). Bone marrow fibrosis was found to be lower at the time of diagnosis in the group that responded good response to first-line treatment (P = 0.01).

Conclusion:
In this study, it was shown that bone marrow fibrosis at diagnosis is an important factor affecting the response to first-line treatment.The degree of bone marrow fibrosis detected at the time of diagnosis in MM may guide the selection of targeted therapy in first-line treatment.
A STUDY ON THE ADVERTISEMENTS RELATED TO SLIMMING PRODUCTS IN PRINT MEDIA AND ITS IMPACT AMONG YOUNGSTERS
Authors: P Sri Jothi , Devi A Jayanthila 
Published: March 2022

Today’s trend there is a noticeable raise in the frequency of advertisements of slimming and weight loss products in print media. Being slim has become an obsession for many people in the last couple of decades. Recently many people do not have conscious about slim toned bodies in naturally, so generally these people should constantly be vigilant in methods that will help lose some fat like diet and other methods to conform to current ideals. Many slimming product sellers employ promotion as a tool to persuade youngsters by inculcating creative ideas. These advertisements are highly exaggerated, and they can easily influence the people especially youngsters who are conscious about their appearance. The major objective of this is to analyze the content of various slimming advertisements in print media and to find out its impact among youngsters. The research methodologies used are content analysis and survey method. Through this study it is evident that slimming advertisements use print media as an effective tool to persuade the target audience.
A Review Article: Protein Engineering of Therapeutic Enzymes
Authors: Zbar Nedhaal Suhail 
Published: March 2022

Through the development of advanced, stimulus-responsive pharmacological systems, protein engineering has the potential to alter the metabolic drug landscapes. Protein therapies are a fast growing category of FDA-approved medications that have the potential to improve clinical consequences in the long run. Protein therapeutics engineering is still in its preliminary phase; however recent advancements in protein engineering skills are being used to gain direct monitoring over pharmacodynamics. Drugs that are intended to be metabolized under specific conditions are known as stimulus-responsive protein medicines. Protein engineering is being used to create biochemically based smart therapies that are personalized to the patient's needs. Protein engineering brings a new features and functionality to the bio-chemical and bio-physical modification of proteins to meet the necessities of therapeutic applications. Provided the enormous capability of protein engineering approaches to modify the activity of bio-catalysts, this review summarizes the current studies are showing the advancements and limitations in using these methods to therapeutic enzyme engineering. The current review will concentrate mainly on three types of therapeutic based enzymes: Diagnostic enzymes, Fibrinolytic enzymes, and pharmaceutical enzymes, in which the protein is the restorative agent, prodrug-activating enzymes, provokes a therapeutic effects, and diagnostic enzymes, in which the remarkable specificity and selectivity of a protein offer advantages compared to conventional analytical techniques.
Energy Transformation Through Primary Productivity and Nutrient Dynamics of Lentic Water
Authors: Kumari Dr. Rashmi , Upadhyay Dr. Manoj Kumar 
Published: March 2022

Some societies can cope, at least temporarily, with pollution and availability constraints. In most of the world, however, population increases continue without significant reduction rates. Growth will continue to impose increasing demands upon freshwater supplies. Control and reversal of degradation requires a proper economic and social valuation of fresh water. Human impact on freshwater ecosystems will increase until industrial growth is stabilized.
Emotionalism and alarmist reactions to the momentum of exploitation by the technological system accomplish little. Understanding the metabolic responses of aquatic ecosystems is essential in order to confront and offset the effects of human alterations. Many small ponds in different parts of the world have been drained or reclaimed to extend arable land. This has caused unusual fluctuations in water land, the impact of which is tremendous. The biodiversity and dynamics of different phytoplankton population are one of the least explored areas in aquatic biology.
Ecological studies give humans a deep insight into principles of life, its forms and levels of existence. F.A forel may be considered as the founder of modern limnology for his original work on Swiss Lakes. The primary social need of every sustainable society is to protect and utilize all their natural resources wisely.
In India, such studies on the pattern of energy flow in aquatic ecosystem by various organisms at different trophic levels are very few. Odum suggested to bring out a comparative picture by investigating the physical, chemical and biological characteristic of lentic water bodies. It is clear that no detailed bioecological investigations have been done so far in this area.
An Observation on Endocrine Glands with Low Secretions but High Effects
Authors: Bigzad Arsalan 
Published: March 2022

The endocrine glands, the products which, are called hormones, located in parts of the body that are generally hidden from view. This system is closely related to the nervous system and the secretions are effective on top of each other and have direct interactions. Various secretions that are secreted in small amounts from cells, sacs and glands are able to affect large areas of membership in a short time. The endocrine glands, together with the nervous system, coordinate the actions and activities of different parts of the body. The endocrine glands are usually classified into three groups. The main endocrine glands, their role is to secrete hormones, including the epiphyseal, adrenal, thyroid, parathyroid, and pituitary glands. Mixed glands - where cells, sacs, and endocrine tissue are located within the exocrine tissue. Such as pancreas, ovaries, testicles, kidneys, thymus, and placenta. Diffuse endocrine system - in which hormone-producing cells are widely distributed in the digestive and respiratory systems.
In terms of effectiveness, its amount is related to the anatomical and physiological needs of the body. Internal disorders of the body and the external environment can cause changes in the number of secretions, which appear as a result of irregularities in the body, which can often be treated by timely diagnosis of the complication; Because the endocrine glands control the body's metabolic rate; Participates in the metabolism of organ materials.
Article Review: Autosomal Dominant Polycystic Kidney Disease: Renal Physiology Diagnosis, Treatment and Novel Therapies
Authors: Hamoode Rana Hazim , Sattar Dalal A. , A. K. Mohanad 
Published: March 2022

In the case of Autosomal dominant polycystic kidney disease, patients are usually cured with Vasopressin (V2) receptor antagonists, which delay the ongoing growth of cyst formation and slow the pace of AD disease progression. Before we know more, it is uncertain if the increase in vasopressin amide levels that was detected during V2RAT treatment impacts the production of glucose in the intestines. Cell growth and fluid secretion are aided by high intracellular concentrations of adenosine 3',5;-cyclic monophosphate (cAMP), which leads to cyst development. SST, a hormone implicated in a variety of cell activities, has the potential to block the generation of intracellular cAMP. Nevertheless, since Somatostatin is quickly removed in vivo, it has little therapeutic promise. As a result, analogues with a longer half-life have been established, which might be potential medicines in the therapy of ADPKD. This review covers the complicated physiological consequences of Somatostatin, especially on the kidneys, as well as the possible therapeutic use of SST analogues in ADPKD.
Chronic intracellular hypoxia as a clustering and stratifying factor for clinical severity grade in nephrotic syndrome in children
Authors: Burlaka Ievgeniia , Mityuryayeva Inga , Bagdasarova Ingretta 
Published: March 2022

Abstract. Nephrotic syndrome is the most common glomerular kidney disease in childhood. It is known that chronic hypoxia is a severe disorder and potent factor of kidney damage. The limited success of existing therapeutic strategies in slowing the progression of chronic kidney disease requires the study of new ways to assess and interpret the levels of chronic intracellular hypoxia concerning basic clinical data, grades of NS activity in children, type of therapeutic response.
The study aimed to investigate the state of transcription factor and marker of intracellular hypoxia HIF-1alfa in children with different degrees of change in basic clinical and laboratory parameters; to evaluate HIF-1alfa as a possible factor of stratification of activity grade of nephrotic syndrome.
Methods. This case-control study was carried out in the duration from June 2018 to August 2020. The study was conducted on 35 selected patients with NS collected from the nephrology department, Pediatric Clinical Hospital №7 (Kyiv, Ukraine). Plasma samples were used to measure marker intracellular hypoxia HIF-1alfa. ANOVA followed by the post hoc Kruskal-Wallis test for multiple comparisons was used to test the significance of differences. GraphPad Prism 9.0 Software for Windows and Statistica 10.0 software used. P values <0,05 considered statistically significant.
Results. Three groups of children with different activity grades were stratified on basis of indicators of proteinuria levels, total blood protein, blood alpha2-globulin levels, serum cholesterol levels, and edema. 1st-grade group found to have a mild increase of HIF-1alfa up to 185-195 a.u. proteinuria 3,5-5,5 g/24 h, total blood protein 47-53 g/L, alfa2-globulins level in blood 20-23 g/L, serum cholesterol level 6-8,5 mMol/L, edema - 1-1.6 points. 2nd grade group found to have moderate increase of HIF-1alfa up to 195,1-205 a.u., proteinuria 5,51-8,5 g/24 h, total blood protein 46,9-40 g/L, alfa2-globulins level in blood 23,1-27 g/L, serum cholesterol level 8.51-10,5 mMol/L, edema 1.61-2.2 points. 3rd-grade group found to have pronounced increase of HIF-1alfa up to 205,1-220 a.u., proteinuria 8,51-14 g/24 h, total blood protein 39,9-32 g/L, alfa2-globulins level in blood 27,1-30 g/L, serum cholesterol level 10.51-13.5 mMol/L, edema 2.21-3 points. Higher HIF-1alfa level appears in children with NS and frequent relapses as compared to the group with rare relapses.
Conclusion. Thus, the increase of HIF-1 alpha to the level of 185-205 a.u., which corresponds to the I-II degree of activity in children with NS can be used as a starting point and therapeutic window for specific anti-hypoxic and antioxidant interventions. Determination of HIF-1 alpha levels in children with NS can be used as a factor for stratification of the activity grade.
Acute cystitis in children: age and regional features in Ukraine
Authors: Saidakova N. , Shulyak О. , Klys A. , Коnonova G. , Нrodzinkiyy V. 
Published: March 2022

Abstract. The present study aimed to evaluate the dynamics of the incidence of acute cystitis in Ukrainian children in the regional aspect.
Methods. The primary documentation is presented by the data of state and branch statistical reports of the institutions of the Ministry of Health of Ukraine for 2013-2017. There are age periods - children under 14 and 15 - 17 years. The indicators were analyzed for Ukraine as a whole, five of its regions, and the regions that make them up.
Results. At stabilization of morbidity of children till 14 years which specific weight reaches 70%, annual growth of sick teenagers (on 28,0% from 2013 to 2017) is noted.
Conclusionі. Administrative areas have been identified that require increased attention from health authorities and clinicians to develop appropriate measures.
Analysis of risk factors of postoperative mortality in peritoneal dialysis patients with developed peritonitis
Authors: Erkent Murathan , Karakaya Emre , Avci Tevfik , Bagci Zeynep Ilayda , Akdur Aydincan 
Published: March 2022

Abstract. Peritoneal dialysis (PD)-associated peritonitis can lead to dysfunction in PD delivery as a result of thickening of the peritoneal membrane, usually due to recurrent peritonitis, and result in peritonitis with ileus or intestinal perforation. This study sought to investigate the risk factors that lead to mortality in patients receiving PD who underwent surgery for peritonitis.
Methods. The study was designed as a retrospective observational study and included 36 patients who received PD and underwent surgical treatment for peritonitis between 2011 and 2020. Data on patient demographics, comorbid diseases, duration of PD application, number of peritonitis episodes due to PD, surgical procedures performed due to peritonitis, and postsurgical morbidity and mortality rates were collected.
Results. It was found that mortality increased with advancing age in patients with coronary artery disease (CAD) compared to those without CAD, and this increase was statistically significant (p = 0.002). In addition, it was determined that the accompanying cirrhosis significantly increased mortality in elderly patients (p = 0.043). In considering the surgical procedures performed, it was found that segmental small-bowel resection (n = 16) was mostly performed due to ileus or intestinal perforation, and no additional pathological findings other than peritonitis were encountered in 12 patients. Mortality occurred in eight patients in the advanced-age group and one patient in the other group among patients operated on for peritonitis. No difference in mortality rate was found according to the surgical procedure (p = 0.512). Binary logistic regression analysis was applied and age, coroner artery diseases (CAD), and dialysis time for risk of mortality. Respectively, age (odds ratio [OR]= 1.09; 95% Cl [1.013-1.193]; p=0.024), CAD [OR] = 43.7; 95% Cl [5.191-368.755]; p <.001 and dialysis time [OR] = 1.786; 95% [1.060-3.010]; p=0.029 was calculated.
Conclusions. Mortality increased by 1.09 times for each one-year increase in age after 52.5 years of age and also CAD increased the mortality rate by 43.7 times. Prolonged PD duration increased the mortality rate especially after 11.5 months, increased the peritonitis-related mortality rate by 1.7 times. We propose that since surgical interventions may be performed in peritonitis due to PD; and do not increase peritonitis-related mortality, an appropriate surgical procedure can be performed safely in experienced centers before it is too late.
SOLIDARITAS SOSIAL MASYARAKAT YANG TERKENA DAMPAK PEMBANGUNAN WADUK JATI GEDE DI DESA CISURAT KABUPATEN SUMEDANG
Authors: Riasih Teta 
Published: March 2022

Solidaritas sosial, kepedulian sosial Â antar warga yang merupakan inti kehidupan sosial menjadi perhatian penelitian ini. Di desa Cisurat terdapat 464 kepala keluarga yang termasuk Orang terkena Dampak Pembangunan (OTD) waduk Jatigede. Â Setelah rumah dan lahannya tergenang waduk Jatigede banyak permasalahan sosial yang muncul dan Â yang paling dominan terjadi perubahan pada dimanika sosial masyarakat Desa Cisurat termasuk persoalan solidaritas sosialnya. Pendekatan penelitian yang digunakan adalah pendekatan kuantitatif survey deskriptif, yang menggambarkan solidaritas sosial masyarakat yang terkena dampak pembangunan waduk Jatigede di desa Cisurat dalam memenuhi kebutuhan keluarganya dengan sampel berjumlah 116 Keluarga. Hasil Â penelitian menunjukkan Â secara keseluruhan, skor solidaritas sosial masyarakat terkena dampak pembangunan waduk Jatigede terhadap pemenuhan kebutuhan hidup keluarga diperoleh 9739, termasuk dalam kategori sedang yang Â Â dilihat dari aspek saling percaya antar warga, Â aspek kesetiaan antar warga, dan aspek sepenanggungan dan kerjasama masyarakat, Â artinya masyarakat yang terkena dampak pembangunan waduk Jatigede aspek senasib sepenanggungannya perlu ditingkatkanÂ Â dan belum bisa mengembangkan kerjasama dalam pemenuhan kebutuhan hidup keluarganya. Sehingga ke depan Â masyarakat bisa ditingkatkan kesadarannya untuk merancang kegiatan bersama yang bisa dijadikan dasar agar solidaritas sosial masyarakat tetap terjaga.Â Kata Kunci:Solidaritas Sosial, Masyarakat terkena dampak Pembangunan. Pemenuhan kebutuhan keluarga.