bluuebunny/crossref_metadata_2025_split huggingface dataset:
Editorial
Authors: Castillo Maza Juan Victoriano 
Published: July 2022

Al cumplir 25 años de labor ininterrumpida en la difusión de la investigación que desarrollan nuestros docentes, graduados de maestrías y doctorado, así como colaboradores nacionales e internacionales, Gestión en el Tercer Milenio revista de investigación de la Facultad de Ciencias Administrativas ha pasado por tres momentos trascendentales: año 1998 iniciamos la publicación del primer número, año 2000 el ISSN (International Standard Serial Number – Número Internacional Normalizado de Publicaciones Seriadas) organismo con sede en París aprobó la asignación del código ISSN a nuestra revista, código numérico reconocido internacionalmente para la identificación de las publicaciones seriadas o en serie y el año 2020 luego de varios años de esfuerzo por lograr su indexación, Latindex una red de 24 instituciones que operan de manera coordinada para reunir y diseminar información sobre las revistas científicas producidas en la región, integrando también las que difunden estudios ibero americanistas en el mundo, luego de una evaluación rigurosa aprueba la indexación e incorporación de la revista Gestión en el Tercer Milenio, que permite hacer uso de los dos servicios de información que ofrece: 1. Directorio, con datos bibliográficos y de contacto de las revistas impresas y en línea registradas y 2. Catálogo 2.0, compuesto por revistas en línea que cumplen con los más altos estándares de calidad.
Comparison of classic and chemometric methods used for phosphate removal from fresh human urine under optimum conditions
Authors: E Öztekin  , S Çolak  , H İnan  
Published: July 2022

Human urine constitutes 1% of domestic wastewater and can be used to recover nitrogen and phosphorus when collected separately at source. Sustainable nutrient (nitrogen, phosphate, potassium) cycling requires the recovery of these valuable resources from human urine. As nitrogen and phosphorus are valuable nutrients needed for plant growth, these components of urine are an excellent fertilizer. Phosphorus can be applied in natural fertilizers and in addition the pollution load of wastewater treatment plants is reduced. Different nutrient removal and recovery methods from urine have been studied at lab scale, but none so far has reached technological competence and none has been extended to practical use. The focus of this study was to evaluate electrocoagulation as a process for the removal of phosphate from fresh human urine using iron plate electrodes. The effect of pH and current density on phosphate removal was investigated. While determining the optimum conditions for removal, classical and chemometric methods were compared. Using the central composite design (CCD), optimum conditions were determined with only 13 experiments, and time and labour savings were achieved compared to the classical method. Initial pH values and current density were controlled within the range of pH 5–9 and current density 12-40 mA/cm2. From the obtained results, it was found that optimal initial current density is 40 mA/cm2 for both methods, and optimal pH is 7 for the classical method and 6.24 for CCD, which is the natural pH of human urine. Realization of phosphate removal using optimum conditions discovered with CCD, provides savings on experimental effort, time, chemicals and energy consumption, and will contribute to resource recovery, reduction of wastewater load and sustainable fertilizer production.
Influence of late radiation complications on long-term survival of patients treated with irradiation of the pelvic organs
Authors: Korytov O. V. 
Published: July 2022

Background. Radiation therapy is one of the main treatments for locally advanced cancers of the rectum, cervix, and prostate. As a result of summing up high total doses, radiation damage occurs in patients.Aim. To determine the frequency of late radiation injuries in patients, their impact on overall survival and quality of life.Materials and methods. The study included 759 patients who received treatment in medical facilities in St. Petersburg and the Leningrad Region, of which 324 were men and 435 were women aged 27–88 years, with a diagnosis of rectal cancer – 257, cervical cancer – 327, prostate cancer – 175 patients. Irradiation was carried out on linear accelerators and brachytherapy devices. The quality of life of patients was assessed by questionnaires based on QLQ-30.Results. The overall toxicity was 35.01 % in patients with cervical cancer, 10.4 % in patients with rectal cancer and 7.6 % in patients with prostate cancer. Overall long-term 5 and 10 years survival in patients with late complications was 46.3 and 16.5 %versus66.5 and 33.4 % in patients without late complications (p= 0.001). In patients diagnosed with rectal cancer, it was significantly higher than in other groups (p<0.05). 3–5 weeks after the end of radiation therapy, patients reported a significant deterioration in the quality of life.Conclusion. Late radiation damage is an important prognostic factor influencing long-term survival in patients diagnosed with cancer of the rectum, cervix and prostate. A decrease in the quality of life in patients who received irradiation of the pelvic organs 3–5 weeks after the end of radiation therapy has been proven.
The features of enzymes activity to nucleoside and antioxidant systems in solid tumors
Authors: Bakurova E. M. , Vasilenko I. V. , Tursunova Yu. D. , Dobaeva N. M. , Borzenko B. G. , Yelsky V. N. 
Published: July 2022

Background. Solid tumors can create their aggressive properties. There are characterized by the invasion and metastatic activity, the resistance of the tumor clone to apoptosis. These pathways triggering may be realized both by 2-deoxy-D-ribose and its phosphorylated form (2-d-D-Rib-1-P), and by hydrogen peroxide.Aim. To investigate the peculiarities of enzymes activity to nucleoside metabolism and antioxidant system in epithelial tumors of different localization.Materials and methods. The features of the thymidine phosphorylase, adenosine deaminase, superoxide dismutase (SOD) and glutathione peroxidase (GPO) activity were studied in tumor homogenates. The visually no transformed tissues of the surgical resection edges were used as a control. Enzymes activity was determined by spectrophotometrical and morphological features were examined by the immunohistochemical methods in tissues of non-small cell lung cancer (NSCLC), samples of gastric and colon carcinomas (GCC).Results. Thymidine phosphorylase activity and adenosine deaminase activity in various malignant tumors were increased in comparison to the control. Respectively, thymidine phosphorylase activity was higher than by 1.8 times (p= 0.002 for NSCLC,p= 0.001 for GCC). An increase of adenosine deaminase activity was revealed both in tissues of NSCLC (more than 1.7 times) and in GCC (by 1.9 times,p= 0.001). No significant changes in SOD activity were detected in the tumors. GPO activity tended to decrease by an average of 1.3 times (p= 0.01 for NSCLC,p= 0.02 for GCC). A cluster analysis of the enzymatic activity features of the studied NSCLC tumors, as well as GCC, revealed their metabolic heterogeneity. According to its results, tumors of different localization were distinguished into 2 clusters. Common feature to their second clusters was an increase the SOD activity. It was accompanied by increase of thymidine phosphorylase activity (p= 0.045 for NSCLC,p= 0.049 for GCC). Therefore, both hydrogen peroxide and 2-d-D-Rib-1-P could be formed in them more intensively. It is important to note that morphological indicators of tumor aggression (decreased or lost expression of cell-cell adhesion marker, expression of mesenchymal markers, active angiogenesis) were detected more frequently in these subgroups.Conclusion. The obtained results reveal that individual features of the enzymes activity in epithelial tumors may be available source of 2-d-D-Rib-1-P and hydrogen peroxide generation in human cancer cells. In the case of individual higher tumor activity of thymidine phosphorylase and SOD and low GPO activity the metabolic stimulation of tumor progression may be occur.
Pattern of neck metastasis in carcinoma of oral tongue-a prospective study of north eastern people
Authors: Saikia Jyotish , Sarma Mridul Kumar , Deka Muktanjalee , Bharadwaj Barasha Sarma 
Published: July 2022

Background: North eastern part of India is one of the most vulnerable regions for all sites of cancer. There is various literature regarding the pattern of cervical metastasis from different sub sites of oral cavity, however there are very few studies from the north eastern part of India, which reports one of the world highest number of cases. The aim and objectives of this study were to study the pattern of cervical lymph node metastasis in relation to prognostic factor like histological grading, laterality, depth of invasion, lymphovascular and perineural invasion and worst pattern of invasion.Methods: A prospective study of 20 patients who had undergone surgery for carcinoma of oral tongue was conducted in State cancer institute in department of Head and neck oncology from January 2020 till June 2021. Out of 20 patients included in the study 6 (30%) were females and 14 (70%) were males. Results: Clinically 9 patients had palpable nodes but pathologically nodes were positive in 10 patients whereas when a node was clinically not palpable in 11 patients, patients was pathologically nodes negative only in 10 patients.2 patients had isolated II involvement. 1 patient has I(b) and level II involvement. 4 patients had level II and III together. Two patients had level II and level IV involvement. 1 patient had level I(A), I(B), III and IV involvement. None of the patient had level 5 involvements.Conclusions: DOI, WPOI and tumor differentiation are the important prognostic parameters. We would also like to suggest surgical excision of the tumor and measurement of WPOI, DOI and assessment of histological grading to be done from frozen section for determining the type of neck dissection in T1/T2 N0 cases.
Malignant psoas syndrome: first pediatric case report in Mexico
Authors: Jorge Iván Martínez-Restrepo , Georgina Velasco-Pérez , Angelica Duarte-Castro , Stefanie Martinez-Restrepo , Héctor Francisco Villa-Santiago 
Published: July 2022

Malignant psoas syndrome (MPS) is a rare, painful condition caused by malignant infiltration of the psoas muscle and adjacent nerves, causing fixed flexion of the leg over the hip. Unfortunately, it is often underdiagnosed. We presented the case of an 8-year-old girl with a clinical history of lumbar embryonal rhabdomyosarcoma and high-grade sarcoma presenting as MPS. To the best of our knowledge, this is the first pediatric case report described in Mexico.
The association of age, gender, education and employment status with potential acceptance of a COVID-19 vaccine in Southern Kerala, India
Authors: Roy Layana , Mathew Seara M. , Raju Christin V. , Joseph Hannah , K. S. Jayakumar , James Roshiny Thankam 
Published: July 2022

Background: Coronavirus disease 2019 (COVID-19) pandemic has affected most the countries causing a devastating influence on world health and economics since its appearance. The accelerated development of the COVID-19 vaccine has become vital, and early data suggests that it is both, safe and efficacious. However, the acceptance of the COVID-19 vaccine depends on several socio-demographic characteristics as well as people’s knowledge and misconceptions. The objective of current study was to access the associations of age, gender, and level of education with vaccine acceptance, from a random sample of 525 participants selected from Kerala, India.Methods: This is a cross-sectional study conducted by analyzing the data collected through a self-administered questionnaire that was shared online and directly across southern Kerala from January 2021 to June 2021. The survey questionnaire consisted of demographic characteristics of the respondents and queries pertaining to knowledge and acceptance of the COVID-19 vaccine.Results: The results of the study showed that the respondents showed a good level of knowledge and acceptance. We conducted this study to understand the attitudes towards COVID-19 vaccines and hesitancy to accept it based on age, gender and educational classification. The age group 18-38 has highest rate of acceptance. A higher rate of acceptance among males and people with higher educational qualification.Conclusions: This research results can be actively used in population segmentation into groups based on their attitudes and this understanding which can be used to develop targeted behavior change communication in improving vaccine acceptance campaigns.
Assessment of hearing outcomes in pre-adolescent cases of otitis media with effusion treated with adenoidectomy
Authors: Rajan Anoop K. , Ravindra Aditi , Sardesai Ishan 
Published: July 2022

<p><strong>Background: </strong>Otitis media with effusion is one of the most common presenting features in children coming to the otorhinolaryngology outpatient with a variety of medical and surgical treatment modalities being offered. This study aims to evaluate post-adenoidectomy hearing outcomes in cases of otitis media with effusion in an attempt to provide long term benefits.</p><p><strong>Methods: </strong>It is a prospective study of 50 pre-adolescent cases in a tertiary care hospital. Pure tone audiometry and tympanometry was performed pre-operatively as well as at regular follow up intervals after adenoidectomy (along with tonsillectomy when indicated). The mean improvement in hearing outcomes was evaluated.</p><p><strong>Results: </strong>The mean hearing improvement when compared to baseline pre-op air-bone gap values were 8.4±6.35, 8.6±6.39, 8.1±6.99 at 15<sup>th</sup> day, 1 month and 2 months post op respectively. There was also a significant shift of tympanometry curves from types B and C pre-op to types A and B 6 months post-op.</p><p><strong>Conclusions:</strong> Adenoidectomy, along with tonsillectomy when indicated, in children with hypertrophied adenoids as well as otitis media with effusion offers very good, long-standing hearing improvement and should always be considered in such patients so as to improve eustachian tube function and eradicate possible source of infection.</p><p><strong> </strong></p>
Comparative study of tympanoplasty using endomeatal approach using tragal cartilage and perichondrium with postauricular approach using temporalis fascia graft
Authors: Yamuna Katari , Lanke Sowmya 
Published: July 2022

<p class="abstract"><strong>Background:</strong> Chronic suppurative otitis media is a disease which is a major cause of morbidity in our country. A large proportion of patients have safe (mucosal) chronic suppurative otitis media which leads to ear discharge and deafness which hampers the productivity of many individuals. Otolaryngologists play an important role in its correction and amelioration by conservative or operative procedures. One such procedure is tympanoplasty.</p><p class="abstract"><strong>Methods:</strong> Patients of either sex having symptoms and signs suggestive of chronic suppurative otitis media and fulfilling the inclusion and exclusion criteria are taken for the study My sample size is 60 and these 60 patients were divided into 2 groups. A. tympanoplasty with temporalis fascia graft. B. tympanoplasty with cartilage island graft. 30 patients were included in each group. </p><p class="abstract"><strong>Results:</strong> In the cartilage island group, the graft uptake rate was 96.7% as compared to the temporalis fascia group in which the same was 90%. There is no significant difference in Air Bne gap between 2 groups.</p><p class="abstract"><strong>Conclusions:</strong> Cartilage Island graft is as good a graft material as temporalis fascia for tympanoplasty.</p>
Developing a ludic framework for counteracting interventions for dementia: A narrative and analytic review
Authors: Innamuri Raviteja , Deshbandhu Aditya , Kattula Dheeraj 
Published: July 2022

As the field of medicine tries to tap into various facets of gamification, the potential of video games and gaming-based interventions has become a hotbed of interesting activity in the Dementia circles of medical research. This paper, exploratory in nature is a bid to find common grounds for the fields of neurosciences, psychology, and psychiatry with the sub-field of ludology in a hope to find unique insights from the benefits of interdisciplinary research and extrapolating findings from gaming addiction.From the perspective of game studies, the paper will draw from elements of concepts like flow, immersion and engagement in a bid to understand the various tools that can be of use if people ailing from neurocognitive disorders were to engage in gaming activity. This paper will lay the framework that will enable the beginning of a matching gaming exercises based on cognitive deficits and psychological profiling of clients diagnosed with neurocognitive disorders and advance the fields of neurosciences and psychology.By combining the findings from existing studies and original work this paper will propose both a means to study the possible effects of gaming-based interventions and suggest ways to streamline and optimize the use of gamification in patient care.
„Określona epoka” w skrzydlatych słowach Wojciecha Młynarskiego
Authors: Wysocka Aneta 
Published: July 2022

Artykuł dotyczy eptonimów pochodzących z piosenek Wojciecha Młynarskiego. W wyniku rekonesansu leksykograficznego i korpusowego wyodrębniono w nim siedemnaście połączeń tego rodzaju. Następnie osiem spośród nich poddano analizie semantyczno-pragmatycznej z wykorzystaniem instrumentarium oferowanego przez lingwistykę antropologiczno-kulturową. Kryterium selekcji fraz stanowił stopień ich osadzenia w kontekście historycznym: wybrano te jednostki, których właściwa interpretacja uwarunkowana jest znajomością realiów życia społecznego epoki PRL. Wskazano na trzy zasadnicze obszary pojęciowe, których owe jednostki dotyczyły: pracę, zabawę oraz media. Obserwacji poddano tekstowe obrazy zjawisk z owych obszarów i na tym tle dokonano semantyczno-pragmatycznej charakterystyki skrzydlatych słów.
Kilka uwag o wybranych niegdysiejszych pomocach do nauczania polszczyzny w środowisku frankofońskim
Authors: Zarębski Rafał 
Published: July 2022

W artykule dokonano charakterystyki wybranych dawniejszych (powstałych w drugiej połowie XIX i na początku XX wieku) podręczników do nauki języka polskiego przeznaczonych dla publiczności frankofońskiej. Zwrócono uwagę na uwarunkowania zewnętrzne (kontekst historyczny, społeczny, instytucjonalny) i wewnętrzne (struktura podręczników, dobór treści tematycznych, rodzaj i jakość materiału egzemplifikacyjnego), które wydają się istotne w opisie tego typu źródeł z zakresu glottodydaktyki historycznej. Postawiono tezę, że zaproponowany sposób opis dawnych źródeł może skutkować holistyczną wizją dawnych podręczników i być pomocny w zapewnieniu im właściwego miejsca w historii polszczyzny.
Working Knowledge
Authors: Belantara Amanda , Drabinski Emily 
Published: July 2022

Cataloging librarians make myriad choices every day as they create the metadata necessary for information retrieval. Each record represents an interaction between the cataloger and the systems they work within and, sometimes, against. Their work is highly constrained by standardized machine-readable fields and codes, controlled subject terms and classification schema. In the exploratory research project Catalogers at Work, the authors use sound recording to reveal the complex yet hidden negotiations embedded in library catalog records.
SMART LIFE STYLES AND ARCHITECTURE FOR SUSTAINABLE WATER MANAGEMENT; PERSPECTIVE FROM A DEVELOPING COUNTRY
Authors: Jawad Nida 
Published: July 2022

Purpose of the study: This study aims to evaluate smart lifestyles, especially in the context of washroom planning, to attain water conservation for sustainable development. Water is one of the essentials of life as we can not imagine our lives without water, so it is the primary need of the day to conserve as much water as we can. It is the harsh reality that water is being wasted without realizing its significance. This study aims to challenge the conventional ways of consuming water in our day-to-day life and aims to bring changes in how we can conserve and preserves this important natural resource. Methodology: To get a clear insight into water conservation as well as its preservation, a survey was conducted at the 45 housing units of Apex Residency PCSIR II Lahore Pakistan which represents the middle class of our society. Interviewed were conducted from different age groups of each family. Water consumed per day by each member was estimated and further compared with water consumption to get a fair idea if they had been using smart lifestyles or not. This study has made an attempt to consider modifications in three basic things; brushing, taking shower and washing hands and face. The data analysis was performed using SPSS ver.22. Main Findings: It was found that 156 liters of water per person is being used in just three activities in a day out of which 46 litres of water per person can be saved daily. However, it is very important to make a plan as to how to preserve it. Applications of the study: local administration of Lahore should devise a local plan for viable water frugality. Smart washroom fixtures are a must while planning smart washrooms. The novelty of the study: This study assessed and evaluated our local population at large and eventually facilitated us with local results, which truly represent how we deal with this important natural resource. We as a Nation need to discuss and analyse all these points in detail and should try to modernize our lifestyles to preserve as much water as we can in our day-to-day life.
Time-optimal trajectory generation in joint space for 6R industrial serial robots using Cuckoo search algorithm
Authors: Karahan Oguzhan , Karci Hasan , Tangel Ali 
Published: July 2022

The trajectory planning problem in industrial robotic applications has recently attracted the great attention of many researchers. In this paper, an optimal trajectory planning approach is proposed based on optimal time by utilizing the interpolation spline method. The method including a combination of cubic spline and 7th order polynomial is used for generating the trajectory in joint space for robot manipulators. Cuckoo Search (CS) optimization algorithm is chosen to optimize the joint trajectories based on objective, including minimizing total traveling time along the whole trajectory. The spline method has been applied to the PUMA robot for optimizing the joint trajectories with the CS algorithm based on the objective. With the trajectory planning method, the joint velocities, accelerations, and jerks along the whole trajectory optimized by CS meet the requirements of the kinematic constraints in the case of the objective. Simulation results validated that the used trajectory planning method based on the proposed algorithm is very effective in comparison with the same methods based on the algorithms proposed by earlier authors.

Keywords: CS; industrial robots; interpolation; spline methods; trajectory planning.