bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of recipes and technologies for ready-to-cook cutlet mass based on minced tilapia
Authors: Dvoryaninova O P , Sokolov A V , Ryadnov S S , Solovyova E A , Syanov D A 
Published: July 2022

Abstract
China is one of the leaders in the supply of fish and seafood to Russia. An illustrative example is the supply of tilapia fish. Today the range of tilapia fish products supplied from China is limited in the Russian food market. It is represented mainly by such products as whole frozen fish and frozen fillets, which, in turn, opens up the prospects for the production of tilapia grown under the conditions of aquaculture in Russia. In this regard, the development of innovative technologies for fish products of wide consumer demand, including ready-to-cook cutlet mass made of tilapia minced meat, is relevant. The studies show that domestic tilapia meat has a number of advantages (protein content, essential amino acids and has a higher biological value (82%)) compared to imported tilapia meat (China). Therefore, it is more advisable to use tilapia meat of local origin in a variety of food products in order to regulate their functional properties, that is, to increase or change the properties of the protein to ensure the stability of the technological process and the quality of the products obtained, as well as to expand the methods of processing and the range of obtained products.
Enzymatic method for obtaining fatty acid concentrate from fish oil
Authors: Petrov B F , Volkova T P 
Published: July 2022

Abstract
Fish oil, depending on the quality, is used for various industries. High-quality oils are used in the pharmaceutical and food industries. Changing the quality of fish oils are associated with the processes of hydrolysis and oxidation. Lower quality oils are used for fodder and technical purposes. One of the areas of fish oils technical use is the production of free fatty acids. Acids are obtained by oil hydrolysis. The enzymatic method of hydrolysis is considered to be promising. The method does not require high energy costs. The enzyme should be immobilized. This ensures the reusability of the enzyme in the technological process. Fish oil acids are distinguished by a high degree of unsaturation of their fatty acid composition. Therefore, these compounds can be used to obtain surface-active, film-forming and antifriction technical products.
Using regression analysis to optimise conditions for water-soluble polysaccharide extraction from sunflower
Authors: Dyakova N A , Gaponov S P , Slivkin A I , Belenova A S , Karlov P M , Lavrov S V 
Published: July 2022

Abstract
Common sunflower roots, often a by-product of the agriculture industry, comprise important raw materials for food and pharmaceutical uses. The purpose of this study was to detect the optimal parameters of ultrasonic extraction of water-soluble polysaccharides from roots of common sunflowers. We varied the grinding of raw materials, the temperature of the extractant, the multiplicity and duration of extraction, the ratio of raw materials to extractant, and the ultrasonic frequency in the bath "Grad 40-35". The data obtained during the experiments made it possible to develop a linear multivariate regression model with sufficient accuracy for forecasting and analysis. The adequacy of the model was confirmed using Pearson's χ2-criterion. For determination of the strength of the general relationship between the predicted and observed data values, the correlation coefficient was used. Findings reveal that the most important conditions for the extraction of annual sunflower roots to obtain the maximum yield were: extraction temperature equal to 80 °C; extraction multiplicity equal to 3; ultrasound frequency equal to 35 kHz; grinding of raw materials into particles measuring between 0.5 mm to 2.0 mm, extraction time of 15 to 20 minutes and the ratio of raw materials to extractant ranging from 1 g per 10 ml to 1 g per 15 ml.
Method based on RIDA®COUNT test systems to evaluate microbial contamination in animal products
Authors: Dorozhkin V I , Denisova E A , Zakharova L L , Goryainova G M , Arsenyeva L V 
Published: July 2022

Abstract
The paper presents the results of a method based on RIDA®COUNT test systems for evaluating the microbial contamination in animal products. These test systems are used to demonstrate the possibility of evaluating bacterial contamination (total microbial contamination, the presence of fungi and yeast, E. Coli, S. Aureus, Salmonella bacteria) in artificially contaminated meat and fish products. The methods were developed and updated for evaluating microbial contamination and fungi based on the RIDA®COUNT test systems.
Study of chronic toxicity of a cereal bar
Authors: Gumerov T Yu , Abrosimov I A , Gabdukaeva L Z , Nurgalieva A R 
Published: July 2022

Abstract
The paper is devoted to the development of a cereal product formulation and the study of its safety indicators. The indicators of chronic toxicity of a food product prepared from traditional grain raw materials and non-traditional vegetable and berry ingredients were studied together with researchers of the Federal Center for Toxicological, Radiation and Biological Safety. The Cereal Bar is made according to TU 10.61.33-009-23333135-2020.
The method of sensory evaluation of cooked sausage using a reference profile
Authors: Kuznetsova T G , Lazarev A A , Derevitzkaya O K , Soldatova N E 
Published: July 2022

Abstract
The use of a food profile-descriptors method is promising for the sensory evaluation of specialized products with defined composition and standardized nutritional value. More than 100 enterprises in the Russian Federation produce the sausage for children’s nutrition (i.e. “For babies”) in accordance with GOST 31498-2012 requirements, whose sausage differs in sensory parameters from enterprise to enterprise. The aim of the work is to create a reference sensory profile of the cooked sausage for children’s nutrition. We used 5 samples of cooked sausages for children’s nutrition as an objects of research. These sausages were produced in accordance with GOST 31498-2018 in various regions of the Russian Federation. The samples were exposed to sensory (organoleptic) evaluation according to the method of scoring (GOST 9959-2015) and the profiling method. The descriptors dictionary was developed in accordance with the requirements of GOST 33609-2015. In order to assess the intensity of descriptors, a 10-point linear structured scale was used. Using the dictionary of descriptors, a reference sensory profile of the cooked sausage for children’s nutrition was developed. The developed reference profile contains a set of key descriptive parameters and characteristics that represent the referenced sensory properties of the food product and their intensity. The profile included 21 descriptors, for each of which a range of permissible deviations in intensity was defined. These measures enable to objectify the results of sausages evaluation and, comparing their sensory parameters, to improve the sensory properties of the food.
Qualimetric vermouth authenticity model
Authors: Kiselev V M , Kiseleva T F , Nikolaeva M A , Petropavlovskaya A V , Plyushcheva L V 
Published: July 2022

Abstract
Modern methods of physical and chemical analysis make it possible to determine the composition of wine with great accuracy, define its belonging to the extended group of the category, as well as to quantify and qualitatively evaluate the foreign impurities contained in it. However, these methods cannot give a complete assessment of wine authenticity, which is based on the complex interaction of the aroma and its components. Therefore, it is impossible to assess the quality of wines, especially special flavored wines, without auxiliary models for organoleptic analysis. A “blind” organoleptic analysis without these models does not allow the taster reliably determining the type and category of wines, as well as their authenticity. This paper presents the method of determining a sample of tasted vermouth as a category of special flavored wines by comparing it with the initial parameters of taste, aroma and bouquet of the “authentic vermouth”. These parameters are presented in the form of two models: schematic five-stage qualimetric and multidimensional mathematical models. All parameters are based on the previously obtained results of the study of unique parameters of taste compositions of the varieties of vermouth samples purchased from retail chains. The veracity of the developed models was tested using the generally recognized triangular diagram of the Vedel’s triangle.
Development of an electrical ozonator for the treatment of agricultural products
Authors: Avdeeva V N , Starodubtseva G P , Bezgina Yu A , Zorina E B , Logacheva E A 
Published: July 2022

Abstract
This article presents an installation for producing ozone. Ozonators have found widespread use in agricultural production. The most efficient means of ozone production today are ozonators using electric discharge. They are simple in design and have high ozone yield in comparison with other methods. The ozonator is designed with the use of discrete elements, CMOS logic elements of medium integration, and operational amplifiers of medium accuracy. The design elements have galvanic connection to the 220/380 V network. The device consists of the following main functional elements: a master oscillator, a signal conditioning device, a display device, an amplifier, a high-voltage output stage and power supplies. This ozonator is intended for use in agricultural production, in particular for the treatment of crops. Experimental trials of the laboratory ozonator were carried out concerning treatment of winter wheat seeds with ozone to improve their sowing qualities. Particularly, winter wheat seeds were subjected to ozone treatment with ozone concentrations of 2.5, 35.0 and 55.0 mg/m3. At these concentrations, the dependence of germination energy of winter wheat seeds on the exposure and settling time from the moment of treatment to seed germination was determined. As a result of research, energy of germination increased by 17.0 % in comparison with the control, germinating capacity in the best variant changed from 77.0 % to 95.0 %.
Signature of lattice dynamics in twisted 2D homo/hetero-bilayers
Authors: Pan Yang , Li Shutong , Rahaman Mahfujur , Milekhin Ilya , Zahn Dietrich R T 
Published: July 2022

Abstract
Twisted 2D bilayer materials are created by artificial stacking of two monolayer crystal networks of 2D materials with a desired twisting angle θ. The material forms a moiré superlattice due to the periodicity of both top and bottom layer crystal structure. The optical properties are modified by lattice reconstruction and phonon renormalization, which makes optical spectroscopy an ideal characterization tool to study novel physics phenomena. Here, we report a Raman investigation on a full period of the twisted bilayer (tB) WSe2 moiré superlattice (i.e. 0

°

⩽

θ

⩽

60∘). We observe that the intensity ratio of two Raman peaks,

B

2
g

and

E

2
g

/

A

1
g

correlates with the evolution of the moiré period. The Raman intensity ratio as a function of twisting angle follows an exponential profile matching the moiré period with two local maxima at 0∘ and 60∘ and a minimum at 30∘. Using a series of temperature-dependent Raman and photoluminescence measurements as well as ab initio calculations, the intensity ratio

I

B

2
g

/

I

E

2
g

/

A

1
g

is explained as a signature of lattice dynamics in tB WSe2 moiré superlattices. By further exploring different material combinations of twisted hetero-bilayers, the results are extended for all kinds of Mo- and W-based transition metal dichalcogenides.
Highly modulated dual semimetal and semiconducting γ-GeSe with strain engineering
Authors: Huan Changmeng , Wang Pu , He Binghan , Cai Yongqing , Ke Qingqing 
Published: July 2022

Abstract
Layered hexagonal γ-GeSe, a new polymorph of germanium selenide (GeSe) synthesized recently, shows strikingly high electronic conductivity in its bulk form (even higher than graphite) while semiconducting in the case of monolayer (1L). In this work, by using first-principles calculations, we demonstrate that, different from its orthorhombic phases of GeSe, the γ-GeSe shows a small spatial anisotropic dependence and a strikingly thickness-dependent behavior with transition from semimetal (bulk, 0.04 eV) to semiconductor (1L, 0.99 eV), and this dual conducting characteristic realized simply with thickness control in γ-GeSe has not been found in other two-dimensional materials before. The lacking of d-orbital allows charge carrier with small effective mass (0.16 m
0 for electron and 0.23 m
0 for hole) which is comparable to phosphorene. Meanwhile, 1L γ-GeSe shows a superior flexibility with Young’s modulus of 86.59 N m−1, only one-quarter of that of graphene and three-quarters of that of MoS2, and Poisson’s ratio of 0.26, suggesting a highly flexible lattice. Interestingly, 1L γ-GeSe shows an in-plane isotropic elastic modulus inherent with hexagonal symmetry while an anisotropic in-plane effective mass owing to shifted valleys around the band edges. We demonstrate the feasibility of strain engineering in inducing indirect–direct and semiconductor–metal transitions resulting from competing bands at the band edges. Our work shows that the free 1L γ-GeSe shows a strong light absorption (∼106 cm−1) and an indirect bandgap with rich valleys at band edges, enabling high carrier concentration and a low rate of direct electron–hole recombination which would be promising for nanoelectronics and solar cell applications.
From Warkworth House to the 21st century care homes: progress marked by persistent challenges
Authors: Gordon Adam L , Spilsbury Karen , Achterberg Wilco P , Adams Rich , Jones Liz , Goodman Claire 
Published: July 2022

Abstract
Long-term care homes play an essential role within health and social care. Successful measures to support older people at home for longer have led to increased prevalence of disability, frailty and cognitive impairment in those who live in care homes over the last two decades. The need for care home places is projected to increase for the next two decades. Modern care homes provide care for people who are predominantly over 80, have multiple long-term conditions, take multiple medicines, are physically dependent and live with cognitive impairment. Residents do better when services recognise the contributions of staff and care home providers rather than treating residents as individual patients living in a communal setting. There is a strong case given residents’ frailty, multimorbidity and disability, that care should be structured around Comprehensive Geriatric Assessment (CGA). Care should be designed to allow opportunities for multiprofessional teams to come together for CGA, particularly if healthcare professionals are based outside care homes. Good data about care homes and residents are central to efforts to deliver high quality care—in some countries, these data are collected but not collated. Collating such data is a priority. Care home staff are under-recognised and underpaid—parity of pay and opportunity with NHS staff is the bare minimum to ensure that the best are recruited and retained in the sector. During the COVID-19 pandemic, residents and relatives have frequently been left out of decisions about policies that affect them, and better consultation is needed to deliver high quality care.
Ascertainment of Incident Cancer by US Population-Based Cancer Registries Versus Self-Reports and Death Certificates in a Nationwide Cohort Study, the US Radiologic Technologists Study
Authors: Liu Danping , Linet Martha S , Albert Paul S , Landgren Annelie M , Kitahara Cari M , Iwan Allison , Clerkin Castine , Kohler Betsy , Alexander Bruce H , Penberthy Lynne 
Published: July 2022

Abstract
Follow-up of US cohort members for incident cancer is time-consuming, is costly, and often results in underascertainment when the traditional methods of self-reporting and/or medical record validation are used. We conducted one of the first large-scale investigations to assess the feasibility, methods, and benefits of linking participants in the US Radiologic Technologists (USRT) Study (n = 146,022) with the majority of US state or regional cancer registries. Follow-up of this cohort has relied primarily on questionnaires (mailed approximately every 10 years) and linkage with the National Death Index. We compared the level of agreement and completeness of questionnaire/death-certificate–based information with that of registry-based (43 registries) incident cancer follow-up in the USRT cohort. Using registry-identified first primary cancers from 1999–2012 as the gold standard, the overall sensitivity was 46.5% for self-reports only and 63.0% for both self-reports and death certificates. Among the 37.0% false-negative reports, 27.8% were due to dropout, while 9.2% were due to misreporting. The USRT cancer reporting patterns differed by cancer type. Our study indicates that linkage to state cancer registries would greatly improve completeness and accuracy of cancer follow-up in comparison with questionnaire self-reporting. These findings support ongoing development of a national US virtual pooled registry with which to streamline cohort linkages.
Analyzing Longitudinally Collected Viral Load Measurements in Youth With Perinatally Acquired HIV Infection: Problems and Possible Remedies
Authors: Brummel Sean S , Van Dyke Russell B , Patel Kunjal , Purswani Murli , Seage George R , Yao Tzy-Jyun , Hazra Rohan , Karalius Brad , Williams Paige L ,   for the Pediatric HIV/AIDS Cohort Study
Published: July 2022

Abstract
Human immunodeficiency virus (HIV) viral load (VL) is an important quantitative marker of disease progression and treatment response in people living with HIV infection, including children with perinatally acquired HIV. Measures of VL are often used to predict different outcomes of interest in this population, such as HIV-associated neurocognitive disorder. One popular approach to summarizing historical viral burden is the area under a time-VL curve (AUC). However, alternative historical VL summaries (HVS) may better answer the research question of interest. In this article, we discuss and contrast the AUC with alternative HVS, including the time-averaged AUC, duration of viremia, percentage of time with suppressed VL, peak VL, and age at peak VL. Using data on youth with perinatally acquired HIV infection from the Pediatric HIV/AIDS Cohort Study Adolescent Master Protocol, we show that HVS and their associations with full-scale intelligence quotient depend on when the VLs were measured. When VL measurements are incomplete, as can be the case in observational studies, analysis results may be subject to selection bias. To alleviate bias, we detail an imputation strategy, and we present a simulation study demonstrating that unbiased estimation of a historical VL summary is possible with a correctly specified imputation model.
Improvement in the binding specificity of anti-isomiroestrol antibodies by expression as fragments under oxidizing conditions inside the SHuffle T7E. colicytoplasm
Authors: Juengsanguanpornsuk Wipawee , Kitisripanya Tharita , Boonsnongcheep Panitch , Yusakul Gorawit , Srisongkram Tarapong , Sakamoto Seiichi , Putalun Waraporn 
Published: July 2022

ABSTRACTSensitive and specific analysis of isomiroestrol (Iso) is required for the quality control of Pueraria candollei, a herb used to treat menopausal disorders. The anti-isomiroestrol monoclonal antibody (Iso-mAb) exhibits cross-reactivity with miroestrol and deoxymiroestrol, which impacts the analytical results. Here, the active and soluble forms of the single-chain variable fragment (Iso-scFv) and fragment antigen-binding (Iso-Fab) against Iso were expressed using Escherichia coli SHuffle® T7 to alter the binding specificity. The Iso-scFv format exhibited a higher binding activity than the Iso-Fab format. The reactivity of Iso-scFv towards Iso was comparable with that of the parental Iso-mAb. Remarkably, the binding specificity of the scFv structure was improved and cross-reactivity against analogs was reduced from 13.3-21.0% to ˂ 1%. The structure of recombinant antibodies affects the binding characteristics. Therefore, the immunoassays should improve specificity; these findings can be useful in agricultural processes and for quality monitoring of P. candollei-related materials.
Timeliness of Point-of-Care Viral Load Results Improves Human Immunodeficiency Virus Monitoring in Nigeria
Authors: Chaplin Beth , Agbaji Oche , Reyes Nieva Harry , Olatunde Bola , Chang Charlotte , Mitruka Kiren , Sule Halima , Dajel Titus , Zee Aaron , Ahmed Mukhtar L , Ahmed Isah , Okonkwo Prosper , Rawizza Holly , Kanki Phyllis 
Published: July 2022

AbstractBackgroundHuman immunodeficiency virus (HIV) viral load (VL) monitoring is critical for antiretroviral therapy (ART) management. Point-of-care (POC) VL testing has been reported to be feasible and preferred over standard-of-care (SOC) testing in many low- and middle-income country settings where rapid results could improve patient outcomes.MethodsThe timeliness of receipt of VL results was evaluated in an open-label, randomized, controlled trial among patients newly initiating ART. Clinical outcomes with POC VL monitoring using Cepheid Xpert vs SOC VL at Jos University Teaching Hospital and Comprehensive Health Centre Zamko in Nigeria were assessed. We determined time between specimen collection and recording of VL in patient charts, receipt of results, and ART switch for those who met virologic failure criteria.ResultsBetween April 2018 and October 2019, we screened 696 ART-naive individuals; 273 were randomized to POC and 268 to SOC HIV-1 VL testing. Participants in the POC arm received VL results significantly faster than those in the SOC arm (0.1 median days, interquartile range [IQR], 0.1–0.2 vs 143.1 days, IQR, 56.0–177.1, respectively; P &lt; .0001). Participants in the POC arm with confirmed virologic failure vs those in the SOC arm were switched more rapidly to a second-line regimen (0 median days, IQR, 0–28 vs 66 days, IQR, 63–123, respectively; P = .03).ConclusionsPOC VL testing resulted in significant improvement in the timeliness of VL result receipt by patients and use for effective HIV clinical management. In patients experiencing VL failure, POC monitoring enabled prompt switching to second-line ART regimens.Clinical Trials RegistrationNCT03533868.