bluuebunny/crossref_metadata_2025_split huggingface dataset:
Microbiome and metabolome in inflammatory bowel disease
Authors: Upadhyay Khushboo G , Desai Devendra C , Ashavaid Tester F , Dherai Alpa J 
Published: October 2022

AbstractInflammatory bowel disease (IBD) is a chronic gastrointestinal disease of unknown etiology, involving complex interactions between the gut microbiome and host immune response. The microbial dysbiosis is well documented in IBD and significantly influences the host metabolic pathways. Thus, a metabolomic fingerprint resulting from the influence of gut dysbiosis in IBD could aid in assessing the disease activity. PubMed, Medline, Science Direct, and Web of Science were searched for studies exploring the association between microbiome and metabolome in IBD patients in the last 5 years. Additionally, references of cited original articles and reviews were further assessed for relevant work. We provide a literature overview of the recent metabolomic studies performed on patients with IBD. The findings report alterations in the metabolite levels of these patients. We also discuss the gut dysbiosis observed in IBD and its influence on host metabolic pathways such as lipids, amino acids, short‐chain fatty acids, and others. IBD, being a chronic idiopathic disease, requires routine monitoring. The available non‐invasive markers have their limitations. The metabolite changes account for both dysbiosis and its influence on the host's immune response and metabolism. A metabolome approach would thus facilitate the identification of surrogate metabolite markers reflecting the disease activity.
A new approach to etching low‐carbon microalloyed steels to reveal prior austenite grain boundaries and the dual‐phase microstructure
Authors: Rodriguez‐Galeano Karol F. , Romano‐Acosta Luis F. , Palmiere Eric J. , Rainforth W. Mark 
Published: October 2022

AbstractA modification to picric acid solutions has been undertaken to reveal the prior‐austenite grain boundaries in microalloyed steels as a result of elemental segregation. It has been found the maximum addition of sodium dodecyl sulphate plus hydrochloric acid to fully reveal both the prior austenite grain boundaries and the final post‐processed structures in these steels.
A Theory‐Based Analysis of Null Causality between HRM Practices and Outcomes: Evidence from Four‐Wave Longitudinal Data
Authors: Ogbonnaya Chidiebere , Daniels Kevin , Messersmith Jake , Rofcanin Yasin 
Published: October 2022

AbstractThe last three decades have seen a growing interest in understanding the influence of human resource management (HRM) practices on employee job satisfaction and organizational performance. While the results have been generally positive, most studies have utilized cross‐sectional research designs, which limit causal inferences. Recently, several studies have used longitudinal data but have not consistently found significant causal links between HRM practices and outcomes after controlling for past outcomes. This points to a tension in the literature that merits further investigation. Drawing on general systems theory (GST), we explore this issue by proposing and testing a set of null causal relationships involving HRM practices, organizational performance (i.e., patient satisfaction), and job satisfaction. We show that average scores on HRM practices and outcomes remain relatively stable at the organizational level over time, such that any observed within‐organization change is likely negligible or non‐significant. Using four‐wave longitudinal data (with two, four, and six‐year time lags) from the public healthcare sector, we argue that the causal links between HRM practices and outcomes are indeed sensitive to the forces of dynamic equilibrium operating within a highly institutionalized context. We use GST to highlight the self‐sustaining nature of HRM systems and discuss the ramifications of this stability for strategic HRM research and practice.
Influence of genetic polymorphisms on mechanical pain sensitivity and endogenous pain modulation of trigeminal and spinal areas
Authors: Soares Flávia Fonseca Carvalho , Ferreira Dyna Mara Araújo Oliveira , Raimundini Amanda Ayla , Dionísio Thiago José , dos Santos Carlos Ferreira , Conti Paulo César Rodrigues , Costa Yuri Martins , Bonjardim Leonardo Rigoldi 
Published: October 2022

AbstractBackgroundPrevious evidence indicates significant association between genetic polymorphisms and phenotypes related to pain sensitivity in patients with temporomandibular disorders (TMD). Despite the important advances in cataloguing diverse factors such as sleep disorders, anxiety and depression, the interrelated mechanisms of painful TMD aetiopathogenesis still need investigation.ObjectivesThis case–control study aimed to evaluate the influence of genetic polymorphisms (rs6296, rs6295, rs1799971, rs4680, rs4633, rs4818) and psychosocial factors on the mechanical pain sensitivity and endogenous pain modulation in women with painful TMD and asymptomatic controls.MethodsWe evaluated six independent variables: anxiety levels, depression, stress, sleep quality, pain catastrophising and genetic polymorphisms, and four dependent variables: mechanical pain threshold (MPT), pressure pain threshold (PPT), wind‐up ratio (WUR) and conditioned pain modulation (CPM) collected at masseter (trigeminal) and hand (spinal) areas in a sample of 95 painful TMD patients and 85 controls. A regression model was used to test the possible effect of the independent variables on dependent variables.ResultsThe regression model was significant for MPT (F11,168 = 9.772; R2 = .390). Painful TMD diagnoses and sleep quality were associated with trigeminal MPT (B coefficient = −.499; and B coefficient = −.211, respectively). WUR was associated with rs6295 and rs6746030, respectively, for the spinal and the trigeminal area.ConclusionGenetic polymorphisms had a slight contribution to endogenous pain modulation as indicated by the significant association with WUR but did not contribute to mechanical pain sensitivity. On the other hand, the presence of painful TMD and the sleep quality contributed significantly to mechanical pain sensitivity.
Optimal location planning of electric bus charging stations with integrated photovoltaic and energy storage system
Authors: Liu Xiaohan , Liu Xiaoyue , Zhang Xingying , Zhou Yirong , Chen Jianli , Ma Xiaolei 
Published: October 2022

AbstractThis study presents a novel bus charging station planning problem considering integrated photovoltaic (PV) and energy storage systems (PESS) to smooth the carbon‐neutral transition of transportation. This paper illustrates a two‐stage stochastic programming model capturing the uncertainty of PV power outputs and designs a step‐wise solution approach in which a conventional charging station location problem is solved in the first step and an improved L‐shaped algorithm is developed in the second step to determine charging station locations with PESS. The numerical experiments indicate that the step‐wise solution approach can provide high‐quality solutions within acceptable computational time. A case study is performed using a real‐world transit network in Beijing, China, with 34 bus routes and 15 candidate bus charging stations. Compared with the benchmark model, both recharging cost and carbon emission are reduced considerably. This paper provides novel insights into the development of integrated transportation and renewable energy systems.
How universal is preference for visual curvature? A systematic review and meta‐analysis
Authors: Chuquichambi Erick G. , Vartanian Oshin , Skov Martin , Corradi Guido B. , Nadal Marcos , Silvia Paul J. , Munar Enric 
Published: October 2022

AbstractEvidence dating back a century shows that humans are sensitive to and exhibit a preference for visual curvature. This effect has been observed in different age groups, human cultures, and primate species, suggesting that a preference for curvature could be universal. At the same time, several studies have found that preference for curvature is modulated by contextual and individual factors, casting doubt on this hypothesis. To resolve these conflicting findings, we conducted a systematic meta‐analysis of studies that have investigated the preference for visual curvature. Our meta‐analysis included 61 studies which provided 106 independent samples and 309 effect sizes. The results of a three‐level random effects model revealed a Hedges’ g of 0.39—consistent with a medium effect size. Further analyses revealed that preference for curvature is moderated by four factors: presentation time, stimulus type, expertise, and task. Together, our results suggest that preference for visual curvature is a reliable but not universal phenomenon and is influenced by factors other than perceptual information.
OPT‐ing out: Root−shoot dynamics are caused by local resource capture and biomass allocation, not optimal partitioning
Authors: Robinson David 
Published: October 2022

AbstractCombining plant growth analysis with a simple model of local resource capture and biomass allocation applied to exemplary experimental data, showed that dynamic changes in allocation to roots when nutrients are scarce is caused by disparities in growth rates between roots and shoots. Whole‐plant growth rates also change but are not caused by an adaptive allocation response. Allocation and whole‐plant growth rate are interdependent, not independent, traits. Following a switch in nutrient availability or partial biomass removal, convergence of allocation and growth rate trajectories does not reflect goal‐seeking behaviour, but the constraints imposed by finite resource availability. Optimal root−shoot allocations are unnecessary to maximise whole‐plant growth rate. Similar growth rates are attainable with different allocations. Changes in allocation cannot maintain or restore a superior whole‐plant growth rate. Roots and shoots do not have to be tightly coordinated but can operate semiautonomously, as their modular construction permits. These findings question the plausibility of the prevailing general explanation of plants' root‐shoot allocation responses, ‘optimal partitioning theory’ (OPT). Local allocation models, not OPT, explain the origins of variability in root−shoot trade‐offs in individuals, the allocation of biomass at global and ecosystem scales and inform selection for allocation plasticity in crop breeding.
Collective practical knowledge is a fragmented interrogative capacity
Authors: Habgood‐Coote Joshua 
Published: October 2022

AbstractWhat does it take for a group of people to know how to do something? An account of collective practical knowledge ought to be compatible with the linguistic evidence about the semantics for collective knowledge‐how ascriptions, be able to explain the practicality of collective knowledge, be able to explain both the connection between individual and collective know‐how and the possibility of a group knowing how to do something none of its members know, and be applicable to a suitably wide range of groups. In this paper I develop a view which can meet all of these desiderata, which combines a Fragmented account of collective knowledge (Habgood‐Coote, 2019a), with the view that practical knowledge is an Interrogative Capacity (Habgood‐Coote, 2019b).
Outlaw epistemologies: Resisting the viciousness of country music's settler ignorance
Authors: Meissner Shelbi Nahwilet , Huebner Bryce 
Published: October 2022

AbstractSettler colonial imaginaries are constructed through the repeated, intergenerational layering of settler ecologies onto Indigenous ecologies; they result in fortified ignorance of the land, Indigenous peoples, and the networks of relationality and responsibility that sustain co‐flourishing. Kyle Whyte (2018) terms this fortification of settler ignorance vicious sedimentation. In this paper, we argue that Outlaw Country music plays important roles in sedimenting settler imaginaries. We begin by clarifying the epistemic dimensions of vicious sedimentation. We then explore specific cases where Outlaw Country songs function as epistemic scaffolding for maintaining and preserving deeply sedimented settler imaginaries. Finally, we conclude by considering ways of using country music as epistemic scaffolding for constructing resistant epistemologies, through the processes of trickster hermeneutics (Vizenor, 1999) and epistemic chronostratigraphy.
Association between PTSD and Impedance Cardiogram‐based contractility metrics during trauma recall: A controlled twin study
Authors: Sheikh Shafa‐at Ali , Perez Alday Erick A. , Rad Ali Bahrami , Levantsevych Oleksiy , Alkhalaf Mhmtjamil , Soudan Majd , Abdulbaki Rami , Haffar Ammer , Smith Nicholas L. , Goldberg Jack , Bremner J. Douglas , Vaccarino Viola , Inan Omer T. , Clifford Gari D. , Shah Amit J. 
Published: October 2022

AbstractPost‐traumatic stress disorder (PTSD) is an independent risk factor for incident heart failure, but the underlying cardiac mechanisms remained elusive. Impedance cardiography (ICG), especially when measured during stress, can help understand the underlying psychophysiological pathways linking PTSD with heart failure. We investigated the association between PTSD and ICG‐based contractility metrics (pre‐ejection period (PEP) and Heather index (HI)) using a controlled twin study design with a laboratory‐based traumatic reminder stressor. PTSD status was assessed using structured clinical interviews. We acquired synchronized electrocardiograms and ICG data while playing personalized‐trauma scripts. Using linear mixed‐effects models, we examined twins as individuals and within PTSD‐discordant pairs. We studied 137 male veterans (48 pairs, 41 unpaired singles) from Vietnam War Era with a mean (standard deviation) age of 68.5(2.5) years. HI during trauma stress was lower in the PTSD vs. non‐PTSD individuals (7.2 vs. 9.3 [ohm/s2], p = .003). PEP reactivity (trauma minus neutral) was also more negative in PTSD vs. non‐PTSD individuals (−7.4 vs. −2.0 [ms], p = .009). The HI and PEP associations with PTSD persisted for adjusted models during trauma and reactivity, respectively. For within‐pair analysis of eight PTSD‐discordant twin pairs (out of 48 pairs), PTSD was associated with lower HI in neutral, trauma, and reactivity, whereas no association was found between PTSD and PEP. PTSD was associated with reduced HI and PEP, especially with trauma recall stress. This combination of increased sympathetic activation and decreased cardiac contractility combined may be concerning for increased heart failure risk after recurrent trauma re‐experiencing in PTSD.
Challenging preservice teachers thinking about school science education with a values and knowledge education (VaKE) experience
Authors: Marangio Karen , Cooper Rebecca 
Published: October 2022

AbstractScience preservice teachers (PSTs), as successes of the school system, often mimic what they experienced as a student when they start teaching, which can be problematic if they never experienced science taught in contextualized ways. Since not all school students report that they find school science relevant, it is important to provide opportunities for PSTs to consider ways to connect science teaching and learning in more relevant ways for their students' lives. Values and knowledge education (VaKE), is a student‐centered pedagogical approach, that uses dilemma stories and a series of purposeful steps to combine values education with knowledge education, provides such an opportunity. This qualitative study investigated secondary science PSTs views on the ways a VaKE experience challenged their assumptions about school science to support their future development as quality teachers of science, and the extent to which PSTs feel confident, able and likely to use VaKE as a teaching strategy in their future teaching of science. VaKE, an innovative pedagogy, provided a powerful and novel learning experience for almost all PSTs, by challenging and inspiring them to critically reflect on their own schooling and expand their pedagogical knowledge for teaching science in the future.
Multisource spatial data integration for use cases applications
Authors: Noardo Francesca 
Published: October 2022

AbstractThe reuse and integration of data give big opportunities, supported by the FAIR data principles. Seamless data integration from heterogenous sources has been an interest of the geospatial community for a long time. However, 3D city models, building information models, and information supporting smart cities present higher semantic and geometrical complexity, which pose new challenges never tackled in a comprehensive methodology. Building on previous theories and studies, this article proposes an overarching workflow and framework for multisource (geo)spatial data integration. It starts from the definition of use case‐based requirements for the integrated data, guides the analysis of integrability of the involved datasets, suggesting actions to harmonize them, until data merging and validation. It is finally tested and exemplified in a case study. This approach allows the development of consistent, well‐documented, and inclusive data integration workflows, for the sake of use case automation in various geospatial domains and the production of interoperable and reusable data.
The compound effect of irradiation and familial pseudohyperkalemia on potassium leak from red blood cells
Authors: Meli Athinoula , Linger Rachel , Stevens‐Hernandez Christian J. , Gyongyver Gyorffy , Marks Denese C. , Aung Htet Htet , Tan Joanne C. G. , Cardigan Rebecca , Bruce Lesley J. , New Helen V. 
Published: October 2022

AbstractBackgroundFamilial pseudohyperkalemia (FP) is a rare asymptomatic condition characterized by an increased rate of potassium leak from red blood cells (RBC) on refrigeration. Gamma irradiation compromises RBC membrane integrity and accelerates potassium leakage. Here, we compared the effect of irradiation, applied early or late in storage, on FP versus non‐FP RBC.Study DesignFive FP and 10 non‐FP individuals from the National Institute for Health Research Cambridge BioResource, UK, and three FP and six non‐FP individuals identified by Australian Red Cross Lifeblood consented to the study. Blood was collected according to standard practice in each center, held overnight at 18–24°C, leucocyte‐depleted, and processed into red cell concentrates (RCC) in Saline Adenine Glucose Mannitol. On Day 1, RCC were split equally into six Red Cell Splits (RCS). Two RCS remained non‐irradiated, two were irradiated on Day 1 and two were irradiated on Day 14. RBCs were tested over cold storage for quality parameters.ResultsAs expected, non‐irradiated FP RCS had significantly higher supernatant potassium levels than controls throughout 28 days of storage (p < .001). When irradiated early, FP RCS released potassium at similar rates to control. When irradiated late, FP RCS supernatants had higher initial post‐irradiation potassium concentration than controls but were similar to controls by the end of storage (14 days post‐irradiation). No other parameters studied showed a significant difference between FP and control.DiscussionFP does not increase the rate of potassium leak from irradiated RBCs. Irradiation may cause a membrane defect similar to that in FP RBCs.
The effect of institutions on the foreign direct investment‐growth nexus: What matters most?
Authors: Li Chengchun , Tanna Sailesh , Nissah Baseerit 
Published: October 2022

AbstractThis paper examines the extent to which host‐country institutions influence the relationship between inward foreign direct investment (FDI) and economic growth. We develop a theoretical model to analyse how different types of institutions condition the FDI‐growth relationship and use various institutional proxies to conduct threshold estimations on panel data for 51 developed and developing countries over the period 1991–2016. Our results consistently reveal a robust, contingent effect of political stability on the FDI‐growth nexus, suggesting that, among all the institutional factors considered, the absence of civil conflict or violence in the host economy is most critical in terms of yielding both direct and indirect growth‐enhancing benefits associated with technology transfer and spillover effects from FDI inflows. This finding is pertinent to both developed and developing countries, although the threshold level of political stability required to achieve sizeable growth benefits from FDI tends to be lower for developing countries.
Diagnostic accuracy of refractometry methods for estimating passive immunity status in neonatal beef calves
Authors: Akköse Mehmet , Buczinski Sebastien , Özbeyaz Ceyhan , Kurban Mert , Cengiz Murat , Polat Yadigar , Aslan Onur 
Published: October 2022

AbstractBackgroundAssessing the inadequate transfer of passive immunity (ITPI) in beef calves is crucial because calves with ITPI are at high risk for morbidity and mortality.ObjectivesThe aim of this study was to determine the accuracy of digital Brix (D‐BRIX) and digital serum total protein (D‐STP) refractometers to estimate different passive immunity status in beef calves and to determine the robustness of thresholds.MethodsBlood samples were collected from 202 (1‐7 days old) beef calves. Serum total solid percentages, total protein concentrations, and IgG concentrations were measured with the D‐BRIX refractometer, D‐STP refractometer, and gold standard radial immunodiffusion (RID) assay, respectively. Data were analyzed using diagnostic test accuracy, areas under the receiver operating characteristics curve, Cohen's kappa coefficient, and misclassification costs analysis to estimate IgG concentrations <10, <16, and <24 mg/mL.ResultsFor the prediction of serum IgG concentrations <10, <16 and <24 mg/mL, the optimal cut‐off values were determined to be <8.5% (Se: 100.0% (95% CI: 87.9‐100.0); Sp: 94.2% [95% CI: 89.6‐97.2]), <8.5% (Se: 92.1% [95% CI: 78.6‐98.2]; Sp: 97.6% [95% CI: 93.9‐99.3]), and <10.1% (Se: 88.8% [95% CI: 79.7‐94.7]; Sp: 67.2% [95% CI: 58.1‐75.4]), respectively, for the D‐BRIX refractometer; and <5.2 g/dL (Se: 100.0% [95% CI: 87.9‐100.0]; Sp: 93.6% [95% CI: 88.9‐96.8]), <5.2 g/dL (Se: 92.1% [95% CI: 78.6‐98.2]; Sp: 97.0% [95% CI: 93.0‐99.0]), and <6.4 g/dL (Se: 87.5% [95% CI: 78.2‐93.8]; Sp: 69.7% [95% CI: 60.7‐77.7]), respectively, for the D‐STP refractometer.ConclusionsThe digital Brix and digital serum total protein refractometers can be used as monitoring tools for assessing passive immunity transfer in neonatal beef calves.