bluuebunny/crossref_metadata_2025_split huggingface dataset:
A comparative study of two grasswren species reveals strong genetic divergence between a peninsula and mainland population
Authors: Vega Aline Gibson , Hall Michelle L. , Ridley Amanda , Cowen Saul J. , Slender Amy L. , Burbidge Allan H. , Louter Marina , Kennington W. Jason 
Published: August 2022

AbstractDispersal patterns dictate genetic population structure, and ultimately population resilience, through maintaining critical ecological processes and genetic diversity. Direct observation of dispersal events is not often possible, but genetic methods offer an alternative method of indirectly measuring dispersal. Here, we use 7 652 genome-wide single-nucleotide polymorphisms (SNPs) to evaluate genetic population structure and infer dispersal capabilities of the Western Grasswren (Amytornis textilis textilis; WGW) in Western Australia (n = 118), utilising a sister species, the Thick-billed Grasswren (Amytornis modestus; TBGW) as a comparison dataset (n = 80). We found genetic divergence and low genetic diversity between two populations (Hamelin and Peron) in the WGW, despite evidence of long dispersal distances within populations by females. In addition, the two WGW populations were found to be more genetically divergent than two described subspecies of TBGW, despite the WGW occurring over a smaller spatial scale. By comparing these two grasswren species, our data suggest a narrow strip of land may be acting as a geographic barrier in the WGW, limiting dispersal between a peninsula population to the mainland. We investigate if morphology aligns with genetic divergence, with some estimates of divergence between WGW populations greater than those between subspecies of TBGW. However, confidence intervals were large, preventing definitive conclusions. Our results support the hypothesis that peninsula populations of small, ground-dwelling birds are genetically isolated from adjacent mainland populations. Furthermore, there is evidence to suggest that the limited gene flow is asymmetrical, with directional dispersal occurring from the bounded peninsula population to the mainland. Our study also highlights how substantial genetic divergence does not necessarily coincide with phenotypic differences.
Host and viral determinants of airborne transmission of SARS-CoV-2 in the Syrian hamster
Authors: Port Julia R. , Morris Dylan H. , Riopelle Jade C. , Yinda Claude Kwe , Avanzato Victoria A. , Holbrook Myndi G. , Bushmaker Trenton , Schulz Jonathan E. , Saturday Taylor A. , Barbian Kent , Russell Colin A. , Perry-Gottschalk Rose , Shaia Carl I. , Martens Craig , Lloyd-Smith James O. , Fischer Robert J. , Munster Vincent J. 
Published: August 2022

SummaryIt remains poorly understood how SARS-CoV-2 infection influences the physiological host factors important for aerosol transmission. We assessed breathing pattern, exhaled droplets, and infectious virus after infection with Alpha and Delta variants of concern (VOC) in the Syrian hamster. Both VOCs displayed a confined window of detectable airborne virus (24-48 h), shorter than compared to oropharyngeal swabs. The loss of airborne shedding was linked to airway constriction resulting in a decrease of fine aerosols (1-10µm) produced, which are suspected to be the major driver of airborne transmission. Male sex was associated with increased viral replication and virus shedding in the air. Next, we compared the transmission efficiency of both variants and found no significant differences. Transmission efficiency varied mostly among donors, 0-100% (including a superspreading event), and aerosol transmission over multiple chain links was representative of natural heterogeneity of exposure dose and downstream viral kinetics. Co-infection with VOCs only occurred when both viruses were shed by the same donor during an increased exposure timeframe (24-48 h). This highlights that assessment of host and virus factors resulting in a differential exhaled particle profile is critical for understanding airborne transmission.
Coyotes in New York city carry variable dog genomic ancestry and influence their interactions with humans
Authors: Caragiulo Anthony , Gaughran Stephen J. , Duncan Neil , Nagy Christopher , Weckel Mark , vonHoldt Bridgett M. 
Published: August 2022

AbstractCoyotes are ubiquitous on the North American landscape as a result of their recent expansion across the continent. They have been documented in the heart of some of the most urbanized cities, such as Chicago, Los Angeles, and New York City. Here, we explored the genomic composition of coyotes in the New York metropolitan area to investigate if genomic demography and admixture differs from expected for urban-dwelling canids. We identified moderate-to-high estimates of relatedness among coyotes living in Queens and adjacent neighborhoods, suggestive of a relatively small population. Although we found low background levels of domestic dog ancestry across most coyotes in our sample, we identified a male suspected to be a first-generation coyote-dog hybrid, as well as his two putative backcrossed offspring that carried approximately 25% dog ancestry. The male coyote-dog hybrid and one backcrossed offspring each carried two mutations that are known to increase human-directed hypersociability in dogs and gray wolves. An additional, unrelated coyote with little dog ancestry also carries two of these mutations. These genetic patterns suggest that gene flow from domestic dogs may become an increasingly important consideration as coyotes continue to inhabit metropolitan regions.
Drying conditions alter the defensive function of seed mucilage against granivores
Authors: LoPresti Eric F. , Stessman Madison E. , Warren Sara E. , Toll Katherine 
Published: August 2022

AbstractEnvironmental conditions alter the function of many plant traits that drive species interactions, producing context-dependency in the outcomes of those interactions. Seed mucilage is a common, convergently-evolved trait found in thousands of plant species. When wetted, the seed coat swells into a viscid mass; when dried, the mucilage strands strongly cement the seed to whatever it is in contact with.This binding to the ground has been previously shown to protect seeds from granivory. Previous research found both that mucilage volume – and the correlated attachment strength – are higher in species from hot, dry, areas suggesting an environmental component of this trait’s function.Here we (1) quantified the effect of temperature on attachment across many species in a lab setting, (2) tested the potential mechanism behind this correlation by accelerating desiccation speed without changing temperature, and (3) tested whether these relationships introduce context dependency of the defensive function of mucilage in the field, using field trials with harvester ants.We found that (1) increasing temperature during mucilage drying strongly reduced the force needed to dislodge seeds for most species, (2) drying time was likely the driving mechanism behind the loss of attachment strength at higher temperatures, not temperatureper se, (3) seeds attached to substrate during higher temperatures or under accelerated drying conditions were far more susceptible to granivory.‘Synthesis’ These results show not only the mechanism behind an abiotic modification of a functional trait of seeds, but that this change majorly alters a key interaction contributing to seed survival. These results add to a small, but growing, literature on the importance of seed mucilage in seed survival and demonstrate strong and largely predictable context-dependency in this trait’s defensive function.
Longitudinal Faecal Calprotectin Profiles Characterise Disease Course Heterogeneity in Crohn’s Disease
Authors: Constantine-Cooke Nathan , Monterrubio-Gómez Karla , Plevris Nikolas , Derikx Lauranne A.A.P , Gros Beatriz , Jones Gareth-Rhys , Marioni Riccardo E. , Lees Charlie W. , Vallejos Catalina A. 
Published: August 2022

AbstractBackground and AimsThe progressive nature of Crohn’s disease is highly variable and hard to predict. In addition, symptoms correlate poorly with mucosal inflammation. There is therefore an urgent need to better characterise the heterogeneity of disease trajectories in Crohn’s disease by utilising objective markers of inflammation. We aimed to better understand this heterogeneity by clustering Crohn’s disease patients with similar longitudinal faecal calprotectin profiles.MethodsLatent class mixed models were used to model faecal calprotectin trajectories within five years of diagnosis and to cluster subjects. Information criteria, alluvial plots, and cluster trajectories were used to decide the optimal number of clusters. Chi-squared, Fisher’s exact test, and ANOVA were used to test for associations with variables commonly assessed at diagnosis.ResultsOur study cohort comprised of 365 patients with newly diagnosed Crohn’s disease and 2856 faecal calprotectin measurements taken within five years of diagnosis (median 7 per subject). Four distinct clusters were identified by characteristic calprotectin profiles: a cluster with consistently high faecal calprotectin and three clusters characterised by different downward longitudinal trends. Cluster membership was significantly associated with smoking (p= 0.015), upper gastrointestinal involvement (p <0.001), and early biologic therapy (p <0.001).ConclusionsOur analysis demonstrates a novel approach to characterising the heterogeneity of Crohn’s disease by using faecal calprotectin. The group profiles do not simply reflect different treatment regimes and do not mirror classical disease progression endpoints. We believe these profiles represent an entirely new way of classifying disease behaviour in Crohn’s disease.
Four decades of phenology in an alpine amphibian: trends, stasis, and climatic drivers
Authors: Lenzi Omar , Grossenbacher Kurt , Zumbach Silvia , Lüscher Beatrice , Althaus Sarah , Schmocker Daniela , Recher Helmut , Thoma Marco , Ozgul Arpat , Schmidt Benedikt R. 
Published: August 2022

AbstractStrong phenological shifts in response to changes in climatic conditions have been reported for many species, including amphibians, which are expected to breed earlier. Phenological shifts in breeding are observed in a wide number of amphibian populations, but less is known about populations living at high elevations, which are predicted to be more sensitive to climate change than lowland populations.The goal of this study is to assess the main factors determining the timing of breeding in an alpine population of the common toad (Bufo bufo) and to describe the observed shifts in its breeding phenology.We modelled the effect of environmental variables on the start and peak dates of the breeding season using 39 years of individual-based data. In addition, we investigated the effect of the lunar cycle, as well as the individual variation in breeding phenology. Finally, to assess the individual heterogeneity in the timing of breeding, we calculated the repeatability of the timing of arrival at the breeding site.Breeding advanced to earlier dates in the first years of the study but the trend continued only until the mid 1990s, and stabilised afterwards. Overall, toads are now breeding on average around 30 days earlier than at the start of the study period. High temperatures and low snow cover in winter and spring, as well as reduced spring precipitation were all associated with earlier breeding. Additionally, we found evidence of males arriving on average before females at the breeding site but no clear and strong effect of the lunar cycle. We only found weak evidence of among-individual variation in shifts in the breeding phenology, as well as a low repeatability of arrival timing.Our findings show that the observed changes in breeding phenology are strongly associated with the environmental conditions. These results contribute to filling a knowledge gap on the effects ssof climate change on alpine amphibian populations. Moreover, we show that changes in phenology, especially in the mountains, can be hard to predict as local microclimatic conditions do not necessarily reflect the observed global climatic trends.
Copy-number dosage regulates telomere maintenance and disease-associated pathways in neuroblastoma
Authors: Burkert Martin , Blanc Eric , Thiessen Nina , Weber Christiane , Toedling Joern , Monti Remo , Dombrowe Victoria M , de Biase Maria Stella , Kaufmann Tom L , Haase Kerstin , Waszak Sebastian M , Eggert Angelika , Beule Dieter , Schulte Johannes H , Ohler Uwe , Schwarz Roland F 
Published: August 2022

ABSTRACTTelomere maintenance in neuroblastoma is linked to poor outcome and caused by either TERT activation or through alternative lengthening of telomeres (ALT). In contrast to TERT activation, commonly caused by genomic rearrangements or MYCN amplification, ALT is less well understood. Alterations at the ATRX locus are key drivers of ALT but only present in ∼50% of ALT tumors.To identify potential new pathways to telomere maintenance, we investigate allele-specific gene dosage effects from whole genomes and transcriptomes in 115 primary neuroblastomas. We show that copy-number dosage deregulates telomere maintenance, genomic stability, and neuronal pathways and identify upregulation of variants of histone H3 and H2A as a potential alternative pathway to ALT. We investigate the interplay between TERT activation, overexpression and copy-number dosage and reveal loss of imprinting at the RTL1 gene associated with poor clinical outcome.These results highlight the importance of gene dosage in key oncogenic mechanisms in neuroblastoma.
Consumer preferences and willingness to pay for eco-labelled eggs: a discrete choice experiment from Chongqing in China
Authors: Liu Chenyu , Liu Xuan , Yao Liuyang , Liu Jie 
Published: August 2022

PurposeThe purpose of this paper is to investigate consumer preference of and willingness to pay for eco-labelled eggs using cross-sectional data collected from Chongqing Municipality in China.Design/methodology/approachThis study employs both conditional logistic model and mixed logistic model to conduct the empirical analysis.FindingsThe empirical results show that individual heterogeneous preference and attributes of eco-labelled eggs significantly influence consumer choices. More specifically, higher per capita income, families with pregnant women or children, higher level of trust in and knowledge of eco-labels contribute positively to choosing eco-labelled eggs, and attributes of eco-labelled eggs such as certification labels, free-range husbandry, and nutrition enrichment significantly increase consumer utility. Generally, the price premium that consumers are willing to pay for eggs containing “organic”, “free-range husbandry”, and “nutrition enrichment” labels is 375.0% more, equivalent to 42.8 Yuan/kg.Originality/valueThis study used first-hand survey data to reveal consumers’ heterogeneous preference of and willingness to pay for eco-labelled eggs based on the random utility theory.
The motivation for corporate energy strategies on energy efficiency among Kenyan firms
Authors: Mungai Edward M. , Ndiritu S. Wagura , Rajwani Tazeeb 
Published: August 2022

Purpose
This study aims to investigate the drivers for adopting energy efficiency practices within an emerging market context.

Design/methodology/approach
Drawing on the shared value theoretical perspective, this study investigates the corporate strategy approaches toward energy efficiency in firms. This paper draws from a sample of 852 Kenyan firms from 14 sectors. This study’s analysis is based on an ordered probit model.

Findings
The findings indicate that companies that conduct energy audits, have environmental performance-based compensation for senior management, provide staff training on energy efficiency and have a written energy policy are more effective in energy efficiency and conservation efforts. Based on the findings, this study recommends that companies and policymakers incentivize corporate actions and strategies to promote energy efficiency. While this study’s findings offer critical insights, the authors recommend future research to make sectorial comparisons.

Originality/value
Studies focusing on drivers of energy efficiency are limited, and those that exist are often either qualitative or focused on large, listed firms. By investigating 852 companies in 14 sectors in Kenya, this study adds to the literature on firms’ energy efficiency management.
Antecedents of “power” and “dependence” in the context of collaborations in construction projects: a systematic literature review
Authors: Deep Shumank , Gajendran Thayaparan , Jefferies Marcus 
Published: August 2022

Purpose
The purpose of this study is to identify the antecedents of “power” and “dependence” attributes in the context of a construction project and to explore the impact of the antecedents on risk transfer and collaboration to develop a conceptual framework for decision-making.

Design/methodology/approach
A systematic review was performed using various databases to identify the antecedents and their measures. This review followed the established preferred reporting items for systematic reviews and meta-analyses protocols and 246 articles were identified. The articles were qualitatively analysed based on keyword co-occurrence approach using VOSviewer software.

Findings
The findings of this systematic review established latent constructs, that is, “clarity of procurement decisions”, “market structure” and “market competition” as antecedents of power and two antecedents of dependence, namely, “reputation” and “commercial importance”. And a framework was conceptualized to determine the contractual approach and the procurement design should be planned to take in account the scenarios and the course of action to enhance collaboration and control risk transfer.

Originality/value
To the best of the authors’ knowledge, this study is the first of its kind to identify the “antecedents” of the attributes of “power” and dependence and framework was conceptualized to determine the contractual approach.
A novel multi-objective optimization method with local search scheme using shuffled complex evolution applied to mechanical engineering problems
Authors: Lobato Fran Sérgio , Libotte Gustavo Barbosa , Platt Gustavo Mendes 
Published: August 2022

PurposeIn this work, the multi-objective optimization shuffled complex evolution is proposed. The algorithm is based on the extension of shuffled complex evolution, by incorporating two classical operators into the original algorithm: the rank ordering and crowding distance. In order to accelerate the convergence process, a Local Search strategy based on the generation of potential candidates by using Latin Hypercube method is also proposed.Design/methodology/approachThe multi-objective optimization shuffled complex evolution is used to accelerate the convergence process and to reduce the number of objective function evaluations.FindingsIn general, the proposed methodology was able to solve a classical mechanical engineering problem with different characteristics. From a statistical point of view, we demonstrated that differences may exist between the proposed methodology and other evolutionary strategies concerning two different metrics (convergence and diversity), for a class of benchmark functions (ZDT functions).Originality/valueThe development of a new numerical method to solve multi-objective optimization problems is the major contribution.
Automatic generation of BIM-based construction schedule: combining an ontology constraint rule and a genetic algorithm
Authors: Wu Zhijiang , Ma Guofeng 
Published: August 2022

PurposeThe purpose of this study is to automatically generate a construction schedule by extracting data from the BIM (Building Information Modeling) model and combining an ontology constraint rule and a genetic algorithm (GA).Design/methodology/approachThis study developed a feasible multi-phase framework to generate the construction schedule automatically through extracting information from the BIM, utilizing the ontology constraint rule to demonstrate the relationships between all the components and finally using the GA to generate the construction schedule.FindingsTo present the functionality of the framework, a prototype case is adopted to show the whole procedure, and the results show that the scheme designed in this study can quickly generate the schedule and ensure that it can satisfy the requirements of logical constraints and time parameter constraints.Practical implicationsA proper utilization of conceptual framework can contribute to the automatic generation of construction schedules and significantly reduce manual errors in the Architectural, Engineering, and Construction (AEC) industry. Moreover, a scheme of BIM-based ontology and GA for construction schedule generation may reduce additional manual work and improve schedule management performance.Social implicationsThe hybrid approach combines the ontology constraint rule and GA proposed in this study, and it is an effective attempt to generate the construction schedule, which provides a direct indicator for the schedule control of the project.Originality/valueIn this study, the data application process of the BIM model is divided into four modules: extraction, processing, optimization, and output. The key technologies including secondary development, ontology theory, and GA are introduced to develop a multi-phase framework for the automatic generation of the construction schedule and to realize the schedule prediction under logical constraints and duration interference.
“More CSR versus more benefits”: how members' motives influence loyalty toward cooperatives
Authors: Lecuyer Charlotte , Béal Mathieu , Capelli Sonia , Sabadie William 
Published: August 2022

Purpose
Co-operative managers must invest appropriately to strengthen member relationships, such as by initiating corporate social responsibility (CSR) actions or providing members with more relational benefits. This paper aims to investigate how members’ motives (collectivistic vs individualistic) might influence the effectiveness of these investments in terms of enhancing members’ trust and loyalty intentions.

Design/methodology/approach
This research combines an exploratory approach, based on six focus groups, with a confirmatory approach based on a field study and two scenario-based experiments.

Findings
Members tend to regard the two motives in contest and infer a “more CSR versus more benefits” arbitration effort by co-operatives, such that they appear to prioritize one motive over the other. Members with individualistic motives principally support co-operatives’ arbitration toward relational benefits, so the positive effects of CSR initiatives on their trust and loyalty intentions are weaker (Study 1). Both CSR and relational benefits can be more or less efficient, depending on members’ motives (Study 2).

Research limitations/implications
Reflecting their contrasting motives, members infer arbitration by co-operative managers, reflected in their “more CSR versus more benefits” belief. This insight and the related implications for trust and loyalty intentions have not been addressed in prior research.

Practical implications
Managers can avoid the negative consequences of “more CSR versus more benefits” inferences by ensuring a good fit between their investments and their members’ prevailing motives. If members have more collectivistic (cf. individualistic) motives, CSR initiatives (cf. relational benefits) enhance their trust and loyalty intentions more effectively.

Originality/value
This research builds on previous work on members’ relationships within co-operatives and on members’ motives. Results find that the effectiveness of co-operatives’ investments to strengthen members’ loyalty intentions depends on members’ prior motives.