bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cross-site collaboration on infection prevention and control research—room for improvement? A 7-year comparative study in five European countries
Authors: Eichel Vanessa M. , Brühwasser Christina , Castro-Sánchez Enrique , Birgand Gabriel , Bathoorn Erik , Salm Florian , Mutters Nico T. 
Published: November 2022

Abstract
Background
The spread of SARS-CoV-2, multidrug-resistant organisms and other healthcare-associated pathogens represents supra-regional challenges for infection prevention and control (IPC) specialists in every European country. To tackle these problems, cross-site research collaboration of IPC specialists is very important. This study assesses the extent and quality of national research collaborations of IPC departments of university hospitals located in Austria, England, France, Germany, and the Netherlands, identifies network gaps, and provides potential solutions.

Methods
Joint publications of IPC heads of all university hospitals of the included countries between 1st of June 2013 until 31st of May 2020 were collected by Pubmed/Medline search. Further, two factors, the journal impact factor and the type/position of authorship, were used to calculate the Scientific Collaboration Impact (SCI) for all included sites; nationwide network analysis was performed.

Results
In five European countries, 95 sites and 125 responsible leaders for IPC who had been in charge during the study period were identified. Some countries such as Austria have only limited national research cooperations, while the Netherlands has established a gapless network. Most effective collaborating university site of each country were Lille with an SCI of 1146, Rotterdam (408), Berlin (268), Sussex (204), and Vienna/Innsbruck (18).

Discussion
The present study indicates major differences and room for improvement in IPC research collaborations within each country and underlines the potential and importance of collaborating in IPC.
“In-between orthorexia” profile: the co-occurrence of pathological and healthy orthorexia among male and female non-clinical adolescents
Authors: Yakın Ecem , Obeid Sahar , Fekih-Romdhane Feten , Soufia Michel , Sawma Toni , Samaha Serena , Mhanna Mariam , Azzi Reine , Mina Anthony , Hallit Souheil 
Published: November 2022

Abstract
Background
The profile of adolescents with orthorexic eating behaviors remains to be explored. This study is the first to explore the typology of Lebanese adolescents from a large non-clinical sample based on orthorexia nervosa (ON) and healthy orthorexia (HO).

Method
A total of 555 adolescents (aged between 15 and 18 years) completed a set of questionnaires assessing orthorexic behaviors, self-esteem, stress, depressive and anxiety symptoms. Cluster analysis based on ON and HO scores was used to identify the typology of the sample. More precisely, this analysis was used to reveal and distinguish between naturally occurring subgroups of individuals with different orthorexic eating profiles, within the studied sample. Further, a series of one-way ANOVA was used to compare observed clusters based on their scores on used questionnaires. This analysis was used to capture the behavioral and psychological differences between previously yielded subgroups of individuals.

Results
Cluster analysis based on ON and HO scores yielded 3 distinct groups: “Low orthorexia”, “Moderate in-between orthorexia” and “High in-between orthorexia”. While the first group represented individuals with no particular (healthy or pathological) interest in healthy eating, the two latter groups represented those with respectively moderate and high degrees of an interest in healthy eating that has both pathological and healthy aspects. Significant differences between clusters regarding their levels of stress, depression, anxiety and self-esteem was observed, yet they were found to be negligible due to poor effect sizes.

Conclusion
Findings from this study suggest that ON and HO can indeed co-occur among adolescents, that this co-occurrence can be experienced at different severity levels. Low effect sizes for ANOVA comparisons may suggest the possibility of the co-occurrence of ON and HO reducing the negative effects of ON behavior to some degree. The potential role of confusion around what constitutes "healthy eating" in the emergence of these "in-between orthorexia" profiles is put forward.
Loss of miR-637 promotes cancer cell stemness via WASH/IL-8 pathway and serves as a novel prognostic marker in esophageal squamous cell carcinoma
Authors: Guo Mengxing , Lian Jingyao , Liu Yaqing , Dong Bo , He Qianyi , Zhao Qitai , Zhang Hongyan , Qi Yu , Zhang Yi , Huang Lan 
Published: November 2022

AbstractBackgroundEsophageal carcinoma is the highly lethal cancer in the world, predominantly in some areas of East Asia. We previously reported that overexpression of cytoskeleton regulator Wiskott-Aldrich syndrome protein and SCAR Homolog (WASH) associates with poor prognosis of patients with esophageal squamous cell carcinoma (ESCC). However, the molecular mechanism and clinical significance involved in WASH overexpression have not been fully elucidated.MethodsBioinformatics analysis and luciferase reporter assay were used to predict and validate miR-637 as a regulator of WASH in ESCC cell lines. qRT-PCR, Western blotting and ELISA assays were performed to examine RNA expression and protein levels, respectively. Next, the biological functions of miR-637 were explored by tumor sphere formation assay in vitro and nude mouse tumor xenograft in vivo. Finally, we evaluated the association of miR-637 levels with clinical features in ESCC patients.ResultsWe identified miR-637 as a WASH-targeting miRNA. miR-637 mimic strongly attenuated the downstream IL-8 production and tumor sphere formation in esophageal cancer cells, whereas miR-637 inhibitor displayed an opposite effect. IL-8 could facilitate stem-like properties and partially rescue the phenotypes induced by miR-637 mimic. Furthermore, miR-637 inhibitor dramatically promoted IL-8 expression and cancer stemness properties in a WASH-dependent manner. Ectopic expression of miR-637 also inhibited tumor growth in a mouse model. Clinically, low expression of miR-637 was observed in tumor tissues and the low expression levels of miR-637 were correlated with poor survival of ESCC patients. In particular, plasma miR-637 could be used as a noninvasive biomarker for ESCC patients.ConclusionsThese results implicate the potential application of miR-637 for diagnosis and prognosis of esophageal cancer.
In Vitro Study to Evaluate the Efficacy of Ultrasonicated Ethanolic Extract of Rosmarinus officinalis and its Chitosan-Based Nanoparticles Against Eimeria tenella Oocysts of Chickens
Authors: Kasem Shaimaa M. , Mira Nabila M. , Mahfouz Magdy E. , Helal Ibrahim B. 
Published: November 2022

AbstractIn this study, chitosan nanoparticles (CsNPs) were used as nanocarrier for ultrasonicated ethanolic extract of Rosmarinus officinalis (UEERO) as a new nanoformulation against Eimeria tenella. Herein, CsNPs have been synthesized by ionic gelation method at pH 3 (CsNPs3) and pH 5 (CsNPs5), followed by characterization of morphology, size, polydispersity index (PDI), surface charge, and loading efficiency of UEERO. An in vitro sporulation inhibition assay (10, 5, 2.5, 1.25, 0.62, 0.31, 0.15, 0.07, 0.04, 0.02, and 0.01 mg/ml normal saline solution) against E. tenella was conducted. Results showed that free CsNPs and UEERO-CsNPs3/5 were cubic- and spherical-shaped with positive charge and average size of ~ 150.8 nm (314.4 nm) and 151.7 nm (321.1 nm), respectively. The total loading efficiency using UV–vis spectrophotometer, was 80.05 at pH 5 and 64.39% at pH 3. The in vitro sporulation inhibition assay revealed that UEERO, CsNPs3/5, and UEERO-CsNPs3/5 showed a potential inhibitory effect on sporulation (%), distortion in wall (%), and sporocyst abnormality (%) in a dose-dependent manner. Accordingly, the concentration (10 mg/ml) showed the best efficacy after 24 h in UEERO, free CsNPs, and UEERO-CsNPs. Moreover, UEERO-CsNPs3 and UEERO-CsNPs5 had stopped the sporulation (%) after 72 h. Taken all together, UEERO-CsNPs3 and UEERO-CsNPs5 are best effective against E. tenella in a dose-dependent manner in terms of sporulation (%), distortion in wall (%), and sporocysts abnormality.
Graphical abstract
How do new therapeutic strategies for PCOS management influence the health of the affected individuals? The narrative review
Authors: Wójcik Aleksandra , Wojtas Jan , Margas Mikołaj , Warchoł Konrad , Stępniak Karol 
Published: November 2022

Introduction and purpose: Management of polycystic ovary syndrome (PCOS) is difficult since the exact pathogenic mechanism has not been established yet. Due to that fact, the substances registered to treat PCOS are still lacking efficacy and are associated with a number of adverse effects. The aim of this study is to review new possible treatment approaches.

State of knowledge: Inositol administered alone or combined with oral contraceptive drugs improves patients’ hormonal status and alleviates the weight increase in comparison to oral contraceptive drugs on their own. Berberine reduces insulin resistance, improves lipid metabolism, and reduces inflammatory reactions. Glucagon-like peptide-1 receptor agonists have a better weight loss effect and less severe adverse reactions than metformin. Thiazolidinediones combined with metformin improve ovulation rate, acne and increase SHGB levels. Thiazolidinediones have also less severe adverse reactions than metformin and can be useful in patients who are not able to tolerate metformin.

Summary: The review has shown that inositol, berberine, glucagon-like peptide-1 receptor agonists andthiazolidinediones have promising therapeutic effects in terms of PCOS treatment, however, more research is needed to establish safety and efficacy of those agents. Nonetheless, results of this study may be utilized in the education of health specialists in endocrinology departments.
Chemoembolization as a minimally invasive treatment of primary malignant liver cancer
Authors: Szklener Katarzyna , Kuryło Weronika , Rodzajewska Anna , Światłowski Łukasz , Jargiełło Tomasz , Mańdziuk Sławomir 
Published: November 2022

Background: Hepatocellular carcinoma (HCC) is the most common type of liver cancer and one of the most malignant neoplasms with high incidence and mortality in humans worldwide. The complex nature of the disease and its high resistance to systemic therapies result in poor prognosis for patients with advanced HCC.
Case Report: In March 2017, the patient was admitted to the Department of Oncological Surgery, where a non-anatomical tumor resection was performed. Three years later, the patient developed a single change in segment 8 of the liver that was a relapse of the neoplastic process. Based on the Bracelon Criteria, the patient was qualified for the 1st stage of chemoembolization using the Seldinger method. In the presented patient as a result of the applied treatment, the neoplastic process was stabilized.
Conclusion: The chemoembolization treatment that was applied to the presented patient turned out to be the correct treatment option. After only the first stage of chemoembolization, the patient regressed the neoplastic lesion.
Risky Sure Things
Authors: Rottenstreich Yuval , Markle Alex , Müller-Trede Johannes 
Published: November 2022

Decision research often takes the variability of potential outcomes as a measure of risk. It thus characterizes sure things, which, by definition, guarantee a specific outcome, as safe. But is this characterization always empirically valid? We show that, when the prevailing reference point is an uncertain option or position, sure things can be perceived as risky rather than safe. Furthermore, preferences may hinge on such perceptions: when construed as risky, sure things can be less appealing. Our findings suggest a perception-based explanation for why the classic tendency to favor sure things over uncertain options is often attenuated given an uncertain reference point. More broadly, they tap an unresolved debate about the determinants of decisions. Much research focuses on taste-based determinants, such as attitudes toward perceived risks, and thereby underplays the critical role of the underlying perceptions. Appreciating the impact of perceptions on decision making leads to novel prescriptive recommendations. This paper was accepted by David Simchi-Levi, decision analysis. Supplemental Material: Data and the online supplement are available at https://doi.org/10.1287/mnsc.2022.4590 .
A Guerra na terra do Sol: cotidiano e mobilização para a Segunda Guerra Mundial em Fortaleza/Ceará
Authors: Barboza Edson Holanda Lima 
Published: November 2022

O artigo aborda os impactos da Segunda Guerra Mundial em Fortaleza, capital do estado do Ceará. Evidencia a participação de movimentos populares e intelectuais, com destaque para os acadêmicos da Faculdade de Direito nas ações de combate ao nazismo, desde palestras nas escolas da capital até as manifestações ocorridas em agosto de 1942, quando a população enfurecida contra os bombardeios de navios brasileiros praticou quebra-quebra e saques em lojas de proprietários de nacionalidades vinculadas aos países do Eixo (Alemanha, Itália e Japão). Discute ainda os impactos da presença de militares norte-americanos que estabeleceram bases em Fortaleza e como o conflito afetou aspectos do cotidiano da cidade. A partir da perspectiva da história social e dialogando com jornais, obras literárias, memorialistas, biografias e depoimentos, problematiza as especificidades locais, entre as quais a seca de 1942, a presença de retirantes e mendigos na cidade e as ações do poder público, que supostamente buscavam prevenir os populares de ataque das nações inimigas, mas que na prática também foram utilizadas como medidas de controle social.
Por uma política de valorização das Revistas acadêmicas na área de História
Authors: Fórum de Editores Associação Nacional de História, 
Published: November 2022

Por uma política de valorização das Revistas acadêmicas na área de História. (Editorial Conjunto) - Fórum de Editores, Associação Nacional de História. Revista Maracanan, PPGH-UERJ, Rio de Janeiro, n. 29, p. 10-15, jan.-abr. 2022.
O AIIB e a securitização do desenvolvimento: a transposição da ameaça chinesa para o financiamento multilateral | The AIIB and the securitization of development: the transposition of the chinese threat to multilateral financing
Authors: Spellmann Samuel 
Published: November 2022

Não são recentes as interpretações da China como uma ameaça aos valores e aos interesses dos Estados Unidos da América (EUA). A percepção da China como ameaça também diz respeito ao crescimento econômico alcançado pelo país asiático. Este processo de securitização é, portanto, transposto para o plano do desenvolvimento econômico. Em decorrência disto, interromper iniciativas transnacionais chinesas de estímulo ao desenvolvimento tornou-se objetivo do Estado Norte-americano. Através de estudo de caso, este artigo aborda o processo de securitização da agenda do desenvolvimento promovida pelo Banco Asiático de Investimentos em Infraestrutura (AIIB) enquanto nova fase da securitização do desenvolvimento da China. Em seu primeiro segmento, recobram-se as bases da teoria da securitização. Após, é exposta a securitização da China, inserindo-a no contexto dos processos de securitização do desenvolvimento e da periferia do capitalismo. O artigo encerra abordando o estudo de caso da agenda do desenvolvimento proposta pelo AIIB. Palavras-chave: China; Securitização do Desenvolvimento; AIIB. ABSTRACTInterpretations of China as a threat to the values and interests of the United States of America (USA) are not new. The perception of China as a threat also concerns the economic growth reached by the Asian country. This process of securitization is, therefore, transposed to the economic development sphere. As a consequence, interrupting Chinese transnational initiatives for development stimulus became an objective for the American State. Using a case study, this paper discusses the process of securitization of the development agenda promoted by the Asian Infrastructure Investment Bank (AIIB) as a new phase of the securitization of China’s development. To so, in its first segment, the theoretical bases for the securitization theory are recovered. Next, the securitization of China is exposed, inserting it in the context of two distinct processes of securitization: the securitization of development; and the securitization of the periphery of capitalism. The last section ends by taking on a case study of the securitization agenda of development proposed by the AIIB.Keywords: China; Securitization of Development; AIIB. Recebido em: 05 ago. 2021 | Aceito em: 18 mai. 2022.
A PROSTITUIÇÃO FEMININA NA AVENIDA W3 NORTE EM BRASÍLIA: CONTRIBUIÇÕES A PARTIR DO CONCEITO FOUCAULTIANO DE DISPOSITIVO
Authors: Silva Cyntia Cristina De Carvalho e , Caruso Haydée 
Published: November 2022

O presente artigo baseia-se em etnografia realizada em uma das mais importantes avenidas de Brasília, a chamada W3 Norte que, entre tantos usos, é conhecida como um dos palcos da prostituição feminina de rua exercida na capital do país. A pesquisa baseia-se, conceitualmente, na proposta foucaultiana de dispositivo, explorada nessa comunicação para refletir sobre a imbricada relação entre a cidade de Brasília, seus contornos arquitetônicos e a apropriação de seus espaços pela prostituição feminina. Ao final, foi possível indicar traços para um dispositivo da prostituição feminina no referido espaço, caracterizado pelo intenso tráfego de veículos, pela separação espacial das atividades, pela cristalização de representações morais, religiosas, médicas, jurídicas e sociais sobre a prostituição feminina, pela objetivação das relações pessoais, discrição, anonimato, praticidade e agilidade da atividade.
A MORADIA COMO SÍMBOLO DE ESTIGMA NA CIDADE DE CAMPOS DOS GOYTACAZES/RJ
Authors: Assis Renan Lubanco 
Published: November 2022

Esta proposta tem por objetivo pensar como as noções acerca do morador de áreas consideradas periféricas são construídas cognitivamente e como operam em determinadas situações sociais da cidade de Campos dos Goytacazes - RJ. Para tal reflexão foram realizados trabalhos de inspiração etnográfica com a duração de dois anos em um bairro tomado como periférico na referida cidade e a análise de conteúdo de notícias impressas de periódicos locais, nos quais a localidade era retratada. Como pano de fundo analítico tomamos emprestadas as noções de “identidade social virtual”, “identidade social real” e “estigma”, da abordagem situacionista goffmaniana, além de outras ferramentas fundamentadas no interacionismo simbólico e na fenomenologia social.
CRAS PARAÍSO: DESAFIO PARA OS ATENDIMENTOS COLETIVOS
Authors: Mazza Yohana Cordova , Diógenes Emanuelle Baptista 
Published: November 2022

O presente artigo pretende desvendar a realidade do território de abrangência do CRAS Paraíso, apresentando seu histórico e ainda seus limites e possibilidades de ação, tendo nos Serviços de Convivência e Fortalecimento de Vínculos a estratégia principal para aproximação com a população de forma coletiva, visando ao fortalecimento de vínculos familiares e comunitários e a prevenção de vulnerabilidades e riscos sociais. O estudo objetiva conhecer os motivos pelos quais os adultos da faixa etária de 18 a 59 anos não participam de grupos de convivência. Pretende-se identificar sugestões para a melhoria da adesão às ações de fortalecimento da convivência familiar e comunitária. Trata-se de estudo qualitativo, exploratório e descritivo sobre o possível esvaziamento das atividades coletivas desenvolvidas no CRAS. Foram utilizados dados da Vigilância Socioassistencial do município de Resende, do ano de 2018, para embasar a pesquisa. Dados esses de extrema importância, tendo em vista o planejamento das ações e, assim, a superação dessa dificuldade vivenciada no CRAS Paraíso.
Bronchopulmonary Complications of Nasogastric tube Placement
Authors: Schreiber Jens , Hachenberg Thomas , Föllner Sebastian , Riedel Sandra 
Published: November 2022

Importance: Nasogastric tube (NGT) placement can cause severe thoracic and non-thoracic complications, which can cause severe morbidity and mortality. The knowledge of predisposing factors is crucial for prevention of these complications. Design: We report on three different cases of severe complication of NGT placement, which have not yet been described. Results: In the first case, intrathoracic malposition of a NGT in a sliding gastric hiatus herniation and repeated insufflations of air for localization control resulted in compression and laceration of the lungs with massive pulmonary hemorrhage. In the second, there was a perforation of both the esophagus and the membranous part of the trachea from the gullet site by a guidewire-containing NGT. In the third case, severe pleuropulmonary complications occurred after short-term intrabronchial malposition. Conclusions: These cases are intended to encourage vigilance to reasons and the clinical course of thoracic complications of NGT placement. Predisposing factors and preventive measures are discussed.
Prevalence and Factors Associated with HIV Status Disclosure among Pregnant and Lactating Women on Antiretroviral Treatment after Rollout of Option B Plus in Urban Moshi Tanzania
Authors: Oshosen Martha , Sabasaba Amon , Ngocho James Samwel , Mmbaga Blandina Theophil 
Published: November 2022

Objective: At the first antenatal visit, HIV counseling and testing are offered to all pregnant women in Tanzania. HIV-infected women are encouraged to disclose their status to the partner. The objective of this study was to determine prevalence and factors associated with HIV status disclosure among pregnant and lactating women on antiretroviral therapy after rollout of Option B plus in urban Moshi.
Methodology: A cross-sectional study was conducted from June to August 2015. Participants were recruited from 4 health facilities in urban Moshi. All HIV-infected women aged 18 years and above attending Prevention of Mother to Child Transmission (PMTCT) clinic were invited to participate. However, pregnant women who receive their test results on the day of enrollment were excluded. The interviews were conducted in Kiswahili language using an interview schedule.
Results: A total of 167 HIV-positive pregnant and lactating women were enrolled in this study. Overall, the prevalence of HIV status disclosure was 74.9%. Most women were married 121 (72.5%) and had primary education 96 (57.5%). Factors that were significantly associated with HIV status disclosure to partner are disclosure counselling (APR=2.11; 95% IC: 1.58-2.84), knowing partner's HIV status (APR=2.16; 95% CI: 1.61- 2.90) and living together with their partner (APR=2.17; 95% IC: 1.61-3.03).
Conclusion: There was a high prevalence of HIV status disclosure to partner. Knowing partner’s status was significantly associated with disclosure. Partner involvement and disclosure counseling is key in HIV disclosure.