bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Sosial Media, Electronic Word Of Mouth Dan Komunitas Terhadap Minat Menggunakan Produk Perbankan Syariah
Authors: Mubarok Hilmy , Naufal Athalla , Putra Egi Perdana , Panorama Maya 
Published: December 2022

Penelitian ini bertujuan untuk mengetahui pengaruh dari variabel media sosial, elekctronic word of mouth, komunitas terhadap mahasiswa febi dalam menggunakan perbankan syariah. Metode yang digunakan dalam menentukan sampel adalah accidental sampling. Sehingga terdapat 30 mahasiswa yang memenuhi kriteria dalam penelitian ini. Metode yang digunakan untuk mengetahui pengaruh antara variable bebas dan terkait ini adalah metode outer model dan inner model. Berdasarkan hasil yang kami dapatkan pada path koefisien diketahui bahwa variabel media sosial dan electronic word of mouth berpengaruh terhadap minat, sedangkan variable komunitas tidak berpengaruh terhadap variable minat. Adjusted R2 menunjukan bahwa penelitian ini memberikan kontribusi terhadap khalayak banyak orang agar penelitian ini bermanfaat dalam kehidupan sehari-hari.
Kata kunci : media sosial, e-wom, komunitas, minat
Storytelling to Support Disease Self-Management by Adults With Type 2 Diabetes
Authors: Gucciardi Enza , Richardson Anna , Aresta Stephanie , Karam Grace , Sidani Souraya , Beanlands Heather , Espin Sherry 
Published: December 2022

<p>Objectives: This pilot project aimed to examine the acceptability and feasibility of a group storytelling intervention to support self-management among adults living with type 2 diabetes.</p>
<p>Methods: Two waves of a single-arm storytelling intervention, consisting of 8 sessions at a community health centre, were delivered to 8 adults with type 2 diabetes. Diabetes educators facilitated each session, in which patients shared stories about diabetes-self-management topics of their choice. Focus groups with both patients and facilitators explored the feasibility and acceptability of the sessions. External raters assessed the fidelity of the intervention's implementation.</p>
<p>Results: Overarching themes describe the acceptability and feasibility of the intervention: 1) the facilitation of patient self-direction, group cohesion, collective learning and support; 2) roles of facilitator educator, and peer learner; 3) the intervention's customization to patients' preferences. The sessions were delivered with high fidelity (averaging 84.4%).</p>
<p>Conclusions: Informal group storytelling enables patients to discuss, understand and give personal meaning to the information that was exchanged, and facilitates educators' better understanding of patients' concerns and gaps in knowledge and how-to strategies that can inform their practice. The group storytelling intervention is acceptable to patients and educators and can be delivered with high fidelity. Further research into effective patient recruitment methods and evaluation of the intervention's impact on diabetes self-management is required. </p>
Perancangan Media Pembelajaran Interaktif Pengenalan Bahasa Inggris untuk Pendidikan Anak Usia Dini (PAUD) Berbasis Android
Authors: Fitriani Leni , Fatimah Dini Destiani Siti , Novitasari Sinta 
Published: December 2022

Era saat ini, usia dini lebih tepengaruhi dengan game yang terdapat pada layer Android dibandingkan game kedaerahan lainnya. Teknologi informasi dapat menjadi perantara untuk dapat memberikan pengalaman baru pada peranti Android, yaitu media pembelajaran yang interaktif. harapan dari observasi ini adalah untuk membuat aplikasi media pembelajaran interaktif untuk mengenalkan bahasa asing khusunya Bahasa inggris untuk PAUD. Masalah yang dihadapi oleh para guru yang mengajar di PAUD tersebut adalah para anak- anak Bahasa inggris sehingga mudah ditiru oleh guru guru kurang menguasai Bahasa inggris, maka diperlukan aplikasi media pembelajaran seperti pelafalan angka dalam Bahasa iggris dengan audio, atau nyanyian, dan untuk memudahkan guru dalam mengajarkan bahasa inggris dengan menarik dan tidak membosankan kepada anak sejak dini. Aplikasi pembelajaran ini dirancang untuk mengatasi dampak negatif penggunaan smartphone pada anak dan mengenalkan bahasa Inggris sejak dini sebagai salah satu materi pembelajaran. Media pembelajaran interaktif ini dirancang untuk membantu anak menajamkan daya ingat dan meningkatkan fokus mereka pada layanan pembelajaran. Selain memberikan pengetahuan dan pembelajaran, juga dapat memberikan hiburan bagi pengguna atau anak. Media pembelajaran interaktif ini memberikan gambaran yang jelas tentang bahasa Inggris sejak dini, membantu anak menguasai pengenalan bahasa Inggris sejak dini, dan memudahkan anak-anak untuk belajar bahasa asing, terutama pengenalan bahasa Inggris ini. Harap dipahami pada usia dini. Perancangan media pembelajaran interaktif pengenalan bahasa Inggris ini mengikuti metodologi MDLC pengembangan multimedia yang terdiri dari enam tahap meliputi konsep, perancangan, dokumentasi materi, pengembangan aplikasi, pengujian, dan penyampaian hasil akhir aplikasi yang menggunakan versi Luther-Sutopo. Prototype atau tujuan aplikasi ini merupakan media pembelajaran interaktif untuk memperkenalkan bahasa Inggris ke pendidikan anak usia dini.
BUSINESS INTELLIGENCE DATA MARKETING MENGUNAKAN METODE KIMBALL DAN ETL DENGAN POWER BI
Authors: Edhya Billah Faktha Putra 
Published: December 2022

Dimasa ini perkembangan teknologi khususnya pada bidang perindustrian semakin pesat, hal tersebut dapat dilihat dari perkembangan teknologi pada bidang penjualan. Pada PT Dipa Pharmalab Intersains, setiap data penjualan disimpan dalam file Excel, yang mana pada aplikasi Excel ini hanya dapat menganalisa beberapa data, itupun tidak bisa dilakukan dengan cepat dan akurat. Dikarenakan aplikasi Excel tidak dapat menampilkan serta mengelompokan data yang ada di dalam perusahaan sesuai kategori dan kriteria perusahaan, maka hal tersebut membuat pengguna mengalami kesulitan untuk dapat menganalisis data penjualan yang dapat berguna untuk membantu perusahaan dalam pembuatan keputusan yang tepat dalam bisnis. Maka dari itu peneliti membuat sebuah sistem dengan menggunakan data warehouse dan aplikasi Power BI yang memiliki tujuan untuk dapat mempermudah proses analisis serta pengambilan keputusan bisnis yang tepat. Dalam penelitian ini menggunakan metode pemodelan data warehouse Kimballl 4 langkah, dimana terdiri dari beberapa proses tahapan antara lain adalah tahap ETL (Extract, Transform dan Load), lalu data yang ada akan diekstrak dalam bentuk tabel dimensi dan fakta, data dimensi dan faktra dapat dimasukan ke dalam MySQL menggunakan aplikasi Pentaho Data Integration, kemudian database akan diolah dan ditampilkan di aplikasi business intelligence Power BI. Pada tampilan Power BI pengguna dapat lebih mudah dalam melihat beberapa informasi yang dapat membantu perusahaan dalam menurunkan kerugian dalam proses produksi seperti informasi ketersediaan stok dan produk dapat dilihat dengan jelas dan dengan menggunakan aplikasi ini pengguna dapat melihat data produk terlaris dan pelanggan yang memiliki tingkat pembelian tertinggi. Hal ini tentunya dapat membantu perusahaan dalam mengambil sebuah keputusan bisnis yang lebih akurat dan tepat.
SISTEM PENGENALAN WAJAH PADA KEAMAAN PINTU OTOMATIS MENGGUNAKAN METODE EIGENFACE BERBASIS RASPBERRY PI
Authors: Luriansyah Rizky Putra , Nugraha Danang Aditya , Harianto Wahyudi 
Published: December 2022

Sistem pengenalan wajah pada keamanan pintu otomatis sangat di perlukan bagi seseorang yang hendak menyimpan barang atau dokumen berharga supaya terhindar dari pencurian barang. Misalnya, pemilik rumah pribadi memiliki barang atau dokumen yang berharga dan pemilik rumah tersebut tidak ingin ada pihak lain yang mencuri barang tersebut maka diaplikasikan system pengenalan wajah pada pintu ruangan penyimpanan barang atau dokumen berharga di dalam rumah supaya hanya si pemilik yang dapat mengakses masuk ke dalam ruangan penyimpanan barang berharga tersebut. Implementasi system pengenalan wajah pada keamanan pintu menggunakan Raspberry pi 3 model B, sensor kamera, modul renal 5-volt, solenoid door lock. Berdasarkan hasil pengujian, system dapat bekerja dengan baik. System yang mendeteksi wajah juga dapat mengenali data sampel valid dan tidak valid dengan baik. Solenoid door lock juga akan membuka relay dengan otomatis jiga wajah yang terdeteksi valid, sebaliknya jika ada wajah yang tidak terdaftar di sampel wajah valid solenoid door lock tidak akan membuka relay tersebut.
The causal relationship between obesity and skin and soft tissue infections: A two-sample Mendelian randomization study
Authors: Hu Hongxin , Mei Jian , Lin Mei , Wu Xianwei , Lin Haibin , Chen Guoli 
Published: December 2022

ObjectiveMany observational studies have shown that obesity strongly affects skin and soft tissue infections (SSTIs). However, whether a causal genetic relationship exists between obesity and SSTIs is unclear.MethodsA two-sample Mendelian randomization (MR) study was used to explore whether obesity is causally associated with SSTIs using a publicly released genome-wide association study (GWAS). An inverse-variance weighted (IVW) analysis was used as the primary analysis, and the results are reported as the odds ratios (ORs). Heterogeneity was tested using Cochran’s Q test and the I2 statistic, and horizontal pleiotropy was tested using the MR−Egger intercept and MR pleiotropy residual sum and outlier (MR-PRESSO).ResultsThe results of the MR analysis showed a positive effect of BMI on SSTIs (OR 1.544, 95% CI 1.399-1.704, P= 5.86 × 10-18). After adjusting for the effect of type 2 diabetes (T2D) and peripheral vascular disease (PVD), the positive effect still existed. Then, we further assessed the effect of BMI on different types of SSTIs. The results showed that BMI caused an increased risk of impetigo, cutaneous abscess, furuncle and carbuncle, cellulitis, pilonidal cyst, and other local infections of skin and subcutaneous tissues, except for acute lymphadenitis. However, the associations disappeared after adjusting for the effect of T2D and PVD, and the associations between BMI and impetigo or cellulitis disappeared. Finally, we assessed the effects of several obesity-related characteristics on SSTIs. Waist circumference, hip circumference, body fat percentage, and whole-body fat mass, excluding waist-to-hip ratio, had a causal effect on an increased risk of SSTIs. However, the associations disappeared after adjusting for the effect of BMI.ConclusionThis study found that obesity had a positive causal effect on SSTIs. Reasonable weight control is a possible way to reduce the occurrence of SSTIs, especially in patients undergoing surgery.
Effect of inactivated COVID-19 vaccines on seizure frequency in patients with epilepsy: A multicenter, prospective study
Authors: Fang Xiqin , Hu Shimin , Han Tao , Yang Tingting , Hu Junji , Song Yucheng , Li Chunxiang , Ma Aihua , Li Yufeng , Kong Qingxia , Tang Liou , Chen Wei , Sun Wenxiu , Fang Chunyan , Sun Yanping , Chen Juan , Sun Wenying , Yan Yibing , Gao Yuxing , Geng Jianhong , Li Nan , Li Qiubo , Jiang Zhaolun , Lv Shishen , Li Wenke , Lang Xiaoling , Wang Suli , Chen Yanxiu , Li Baomin , Li Ling , Liu Xinjie , Liu Yong , Zhan Yan , Gao Zaifen , Qu Lixin , Fu Qingxi , Liu Xuewu 
Published: December 2022

ObjectivesSeveral COVID-19 vaccines list “uncontrolled epilepsy” as a contraindication for vaccination. This consequently restricts vaccination against COVID-19 in patients with epilepsy (PWE). However, there is no strong evidence that COVID-19 vaccination can exacerbate conditions in PWE. This study aims to determine the impact of COVID-19 vaccination on PWE.MethodsPWE were prospectively recruited from 25 epilepsy centers. We recorded the seizure frequency at three time periods (one month before the first vaccination and one month after the first and second vaccinations). A generalized linear mixed-effects model (GLMM) was used for analysis, and the adjusted incidence rate ratio (AIRR) with 95% CI was presented and interpreted accordingly.ResultsOverall, 859 PWE were included in the analysis. Thirty-one (3.6%) and 35 (4.1%) patients were found to have increased seizure frequency after the two doses, respectively. Age had an interaction with time. The seizure frequency in adults decreased by 81% after the first dose (AIRR=0.19, 95% CI:0.11–0.34) and 85% after the second dose (AIRR=0.16, 95% CI:0.08–0.30). In juveniles (&lt;18), it was 25% (AIRR=0.75, 95% CI:0.42–1.34) and 51% (AIRR=0.49, 95% CI:0.25–0.95), respectively. Interval between the last seizure before vaccination and the first dose of vaccination (ILSFV) had a significant effect on seizure frequency after vaccination. Seizure frequency in PWE with hereditary epilepsy after vaccination was significantly higher than that in PWE with unknown etiology (AIRR=1.95, 95% CI: 1.17–3.24). Two hundred and seventeen (25.3%) patients experienced non-epileptic but not serious adverse reactions.DiscussionThe inactivated COVID-19 vaccine does not significantly increase seizure frequency in PWE. The limitations of vaccination in PWE should focus on aspects other than control status. Juvenile PWE should be of greater concern after vaccination because they have lower safety. Finally, PWE should not reduce the dosage of anti-seizure medication during the peri-vaccination period.
Effect of dietary oregano oil on growth performance, disease resistance, intestinal morphology, immunity, and microbiota of hybrid grouper (Epinephelus fuscoguttatus ♀ × Epinephelus lanceolatus ♂)
Authors: Xin Yu , Liu Hao , Yan Xiaobo , Huang Weibin , Pan Simiao , Zhou Menglong , Lu Baiquan , Tan Beiping , Dong Xiaohui , Yang Yuanzhi 
Published: December 2022

The study aimed to investigate the effects of oregano oil (OO) supplement in the diet on the growth performance, disease resistance, immunity, and intestinal health of hybrid grouper. Six isonitrogenous and isolipidic diets were fed to the grouper with an initial weight of 19.10 ± 0.12 g for 8 weeks, of which the dietary OO levels were 0 (Control), 0.1 (OO-0.1), 0.3 (OO-0.3), 0.6 (OO-0.6), 0.9 (OO-0.9), or 1.2 (OO-1.2) g kg-1. The results showed that there were no significant differences in growth performance among the six groups, while the OO supplement could improve the disease resistance ability of grouper. Our findings have demonstrated that the OO supplement, especially 0.3 g kg-1, could improve the intestinal morphology via increasing the villus number and muscle thickness and elevate digestive enzyme activities such as those of amylase (AMS) and lipase. The 0.3-g kg-1 OO supplement also can activate the antioxidant defense system, reduce nuclear factor erythroid 2-related factor 2-like 2 (Nrf2)/Kelch-like-ECH-associated protein 1 (Keap1) expression, and then enhance the immune ability via acid phosphatase (ACP), lysozyme (LYS), complement C3 (C3), and tight junction-associated signaling pathways in hybrid grouper. Meanwhile, the relative abundance of Firmicutes and Bacteroidetes in the OO-0.3 group was significantly higher than that of Control group (P&lt; 0.05), while the relative abundance of Proteobacteria showed a basically opposite trend (P&lt; 0.05). These findings suggested that dietary OO supplementation could significantly improve intestinal health and induce the antioxidant defense system and immunity, which means that OO could be used as a functional feed additive to protect the intestine, and the appropriate addition level of OO should be 0.3 g kg-1.
Tubridge flow diverter alone vs. Tubridge flow diverter and coils for the treatment of intracranial aneurysms: A propensity score matching analysis
Authors: Shi Min , Feng Yu , Zhang Cheng-Da , Tang Qing-Wen , Li Ze-Jin , Zhao Wen-Yuan , Zhang Ting-Bao 
Published: December 2022

BackgroundThe study was designed to assess the clinical performance of a tubridge flow diverter (TFD) in the treatment of intracranial aneurysms and to compare the efficacy and safety between intracranial aneurysms treated with TFD alone and TFD combined with coiling.MethodsIn this retrospective study, patients treated with the TFD alone or TFD combined with coiling between June 2018 to November 2022 were included. The patient demographics, the characteristics of the aneurysm, and the treatment outcomes between the two groups were compared. Propensity score matching was performed to match the variables with a significant difference between groups.ResultsIn the current study, data from 93 consecutive patients including 104 aneurysms treated with TFD were analyzed. In total, 43 patients with 49 aneurysms were treated with TFD alone, and 50 patients with 55 aneurysms were treated with TFD combined with coiling. Aneurysms in the TFD combined with the coiling group were larger (12.9 ± 8.6 vs. 8.7 ± 8.8 mm, P = 0.016) and more likely to be saccular (92.7% vs. 75.5%, P = 0.027) than in the TFD alone group. No significant difference was observed between the two groups in terms of perioperative complication rate. During the follow-up period, the complete occlusion rate in the TFD combined with the coiling group was higher (80.0% vs. 43.8%, P = 0.001) than in the TFD alone group. These results were further confirmed using a propensity score matching analysis.ConclusionTFD combined with coiling can be a safe and effective alternative option for the treatment of complex aneurysms. Given the potential risks of these therapeutic modalities, thus very careful consideration is required on an individual patient basis.
Lack of neural contributions to the summating potential in humans with Meniere’s disease
Authors: Riggs William J. , Fontenot Tatyana E. , Hiss Meghan M. , Varadarajan Varun , Moberly Aaron C. , Adunka Oliver F. , Fitzpatrick Douglas C. 
Published: December 2022

ObjectiveTo investigate the electrophysiology of the cochlear summating potential (SP) in patients with Meniere’s disease (MD). Although long considered a purely hair cell potential, recent studies show a neural contribution to the SP. Patients with MD have an enhanced SP compared to those without the disease. Consequently, this study was to determine if the enhancement of the SP was in whole or part due to neural dysfunction.DesignStudy participants included 41 adults with MD and 53 subjects with auditory neuropathy spectrum disorder (ANSD), undergoing surgery where the round window was accessible. ANSD is a condition with known neural dysfunction, and thus represents a control group for the study. The ANSD subjects and 17 of the MD subjects were undergoing cochlear implantation (CI) surgery; the remaining MD subjects were undergoing either endolymphatic sac decompression or labyrinthectomy to alleviate the symptoms of MD. Electrocochleography was recorded from the round window using high intensity (90 dB nHL) tone bursts. The SP and compound action potential (CAP) were measured to high frequencies (&gt; = 2 kHz) and the SP, cochlear microphonic (CM) and auditory nerve neurophonic (ANN) to low frequencies. Linear mixed models were used to assess differences between MD and ANSD subjects.ResultsAcross frequencies, the MD subjects had smaller alternating current (AC) response than the ANSD subjects (F = 31.61,534, p &lt; 0.001), but the SP magnitudes were larger (F = 94.31,534, p &lt; 0.001). For frequencies less than 4 kHz the SP magnitude in the MD group was significantly correlated with the magnitude of the CM (p’s &lt; 0.001) but not in the ANSD group (p’s &gt; 0.05). Finally, the relative proportions of both ANN and CAP were greater in MD compared to ANSD subjects. The shapes of the waveforms in the MD subjects showed the presence of multiple components contributing to the SP, including outer and inner hair cells and neural activity.ConclusionThe results support the view that the increased negative polarity SP in MD subjects is due to a change in the operating point of hair cells rather than a loss of neural contribution. The steady-state SP to tones in human subjects is a mixture of different sources with different polarities.
Acquired von Willebrand syndrome is common in infants with systemic-to-pulmonary shunts: Retrospective case-series
Authors: Icheva Vanya , Budde Ulrich , Magunia Harry , Jaschonek Karl , Hinterleitner Clemens , Neunhoeffer Felix , Schlensak Christian , Hofbeck Michael , Wiegand Gesa 
Published: December 2022

BackgroundAlthough acquired von Willebrand syndrome (aVWS) has been described in congenital heart disease before, anatomical features leading to aVWS with characteristic reduction or loss of high molecular weight von Willebrand multimers (HMWM) are not well known. This study assesses the prevalence and effects of aVWS in infants with systemic-to-pulmonary shunts (SPS).MethodsThis retrospective single-center study analyzes diagnostic data of infants with complex congenital heart defects requiring palliation with SPS. During the study period between 12/15–01/17 fifteen consecutive patients were eligible for analysis. Results of von Willebrand factor antigen (VWF:Ag), collagen binding activity (VWF:CB) and von Willebrand factor multimer analysis were included.ResultsIn all 15 patients with SPS an aVWS could be found. Blood samples were collected between 5 and 257 days after shunt implantation (median 64 days). None of the patients demonstrated increased bleeding in everyday life. However, 6 out of 15 patients (40%) showed postoperative bleeding complications after SPS implantation. Following shunt excision multimeric pattern normalized in 8 of 10 (80%) patients studied.ConclusionsThis study shows that in patients undergoing SPS implantation aVWS might emerge. Pathogenesis can be explained by shear stress resulting from turbulent flow within the shunt. Knowledge of aVWS existence is important for the consideration of replacement therapy with von Willebrand factor containing products and antifibrinolytic treatment in bleeding situations. Implementation of methods for rapid aVWS detection is required to achieve differentiated hemostatic therapy and reduce the risk of complications caused by empiric replacement therapy.
A novel cuproptosis-related gene signature predicting overall survival in pediatric neuroblastoma patients
Authors: Yang Hu , Yang Jun , Bian Hongqiang , Wang Xin 
Published: December 2022

BackgroundCuproptosis is a novel cell death pathway, and the regulatory mechanism in pediatric neuroblastoma (NB) remains to be explored. We amid to investigate cuproptosis-related genes (CRGs) and construct a novel prognostic model for NB.MethodsTo evaluate the role of CRGs on the clinical outcome of pediatric NB, the dataset of pediatric patients with NB of GSE49710 dataset was used to identify CRGs in association with patient overall survival (OS), and TARGET database was used to validate the predictive value of cuproptosis-related signature (CRG-score). The correlation between the CRG-score and the tumor microenvironment (TME), clinicopathological parameters, chemotherapy, and the response to immunotherapy was explored.ResultsOverall, 31 CRGs were associated with OS in the univariate Cox regression analysis. Then, a prognostic model incorporating 9 CRGs was established with the LASSO regression analysis, which could classify all NB patients into two CRG-score groups. The performance of the signature was verified in both internal and external validation cohorts. Multivariate analysis indicated that the CRG-score was an independent prognostic indicator, and stratification analysis still showed a high predictive ability for survival prediction. The CRG-score was associated with age, MYCN status, INSS stage, and COG risk. Additionally, the higher CRG-score group exhibited lower immune scores, immune cell infiltration, and decreased expression of immune checkpoints. Meanwhile, the CRG-score could predict the drug sensitivity of administering chemotherapeutic agents for NB patients.ConclusionsOur comprehensive analysis of cuproptosis-associated genes in NB provides a new approach for the prediction of clinical outcomes and more effective treatment strategies.