050 Feasibility of Adding a Sexual Function Questionnaire to a Preconception Cohort Study
Authors: Bond J. , White K. , Wise L. 
Published: May 2022

ABSTRACT

Introduction
Sexual dysfunction is estimated to affect over 40% of women and influences intercourse frequency and enjoyment. Despite its critical role in conception, little research has focused on sexual function during the preconception period.

Objective
We assessed the feasibility of adding a sexual function questionnaire to an ongoing preconception cohort study.

Methods
The [blinded preconception cohort study] began in 2013 and has prospectively enrolled over 15,000 women aged 21-45 years to date. Women planning a pregnancy are recruited primarily via online advertisements on social media. In March 2021, a supplemental survey module on sexual health and wellness was added to the study protocol. This survey included 32 questions on a range of topics related to sexual health, including the 6-item Female Sexual Function Index, questions about orgasm, and patient-provider communication about sexual health during preconception health care visits. The supplemental survey takes approximately 5-7 minutes to complete. Participants were invited to complete the supplemental questionnaire 30 days after enrolling and completing the baseline questionnaire.

Results
Of the 406 participants who started the survey, 397 (97.8%) completed it. The sample was primarily between 25 and 34 years old, with 54% having been trying to conceive for 0-1 months. The vast majority of the sample (87.1%) had been trying to conceive for 6 months or fewer. Eighty percent of the participants lived in the United States, and 20% lived in Canada. The vast majority (84.2%) were married. One-hundred thirty-seven participants (34.3%) reported experiencing painful intercourse at least sometimes in the past four weeks. Ninety-nine (24.5%) participants reported no, very low, or low sexual desire or interest in the past four weeks. Sixty-seven (16.5%) participants reported low or very low levels of arousal during sexual activity. Seventy (17.5%) participants reported being very or moderately dissatisfied with their sex lives in the past four weeks. The majority of women (80.9%) reported seeing a healthcare provider for a preconception counseling visit at some point prior to enrollment. Of these, 238 (74.1%) did not discuss sexual issues during the visit, even though 35% were experiencing them. Participants readily provided details in the open-ended text fields, indicating a willingness to share their information with investigators.

Conclusions
Our results suggest that incorporation of a detailed questionnaire about sexual function was acceptable to a large number of participants in a preconception cohort study. Our preliminary results will provide valuable insights into the sexual function and health of women in the preconception period.

Disclosure
Work supported by industry: yes, by This cohort study has received in-kind donations from Swiss Precision Diagnostics, Sandstone Diagnostics, Fertility- Friend.com, and Kindara.com for primary data collection. A consultant, employee (part time or full time) or shareholder is among the authors (Lauren Wise has served as a consultant for AbbVie, Inc).