bluuebunny/crossref_metadata_2025_split huggingface dataset:
Survey of Authorship Identification Tasks on Arabic Texts
Authors: Alqahtani Fatimah , Dohler Mischa 
Published: September 2022

Authorship identification is the process of extracting and analysing the writing styles of authors to identify the authorship. From the writing style, the author and his/her different characteristics can be recognised, which is very useful in digital forensics and cyber investigations. In the literature, authorship identification tasks were addressed on both long and short documents and performed on different languages, such as English, Arabic, Chinese, and Greek. This survey has reviewed the authorship identification tasks for the Arabic language to contribute to this area of research by exploring Arabic language performance and challenges. A total of 27 prominent Arabic studies of each authorship identification domain were reviewed considering the used data, selected features, utilised methods, and results. After a review of the various studies, it was concluded that the results of authorship identification tasks vary based on mostly the selected features and used dataset. Furthermore, the effective features differ from one dataset to another based on the various types of the Arabic language. However, all authorship identification tasks involving the Arabic language face considerable challenges with data pre-processing due to the challenging Arabic concatenative morphology.
Research of the Coronavirus Anxiety, Post-Traumatic Stress, Generalized Anxiety Disorder, Quality of Life, and Stress Coping Styles in COVID-19 Survivors
Authors: Korkut Süleyman 
Published: September 2022

The COVID-19 survivors suffer from severe psychosocial challenges related to the current pandemic. In this context, it was aimed to evaluate the coronavirus anxiety, generalized anxiety disorder (GAD), and post-traumatic stress symptoms (PTSS) and also determine the quality of life (QOL), and coping styles with stress in survivors by comparing them with non-COVID controls (NCs). This study was conducted from April 15 to October 15, 2021, as a cross-sectional study design. The study included 339 survivors who were confirmed with COVID-19 through clinical tests in the last 3 months and 321 NCs who had not been infected with COVID-19. Besides sociodemographic and clinical data, a set of valid and reliable assessment tools were used to measure outcomes of coronavirus anxiety, coping styles, post-traumatic stress, generalized anxiety, and quality of life. The total scores of IES-R, GAD-7, and CAS were significantly higher in survivors than in the NCs. These results revealed that survivors manifested higher levels of coronavirus anxiety, generalized anxiety, and post-traumatic stress symptoms (p < 0.05). In survivors, the rates of GAD and coronavirus anxiety were found to be 59.3% and 25.7%, respectively. Additionally, the majority of survivors (89.4%) reported the severity of anxiety as moderate to severe, and also almost two-thirds of them reported the psychological impact of the pandemic as moderate to severe. Furthermore, survivors were found to have a lower quality of life. The findings of this study indicate that survivors experienced higher levels of coronavirus anxiety, generalized anxiety, and post-traumatic stress, and had lower QOL. In addition, it was determined that survivors haven't been using active styles adequately in coping with stress. Thus, psychological intervention studies should be conducted and public mental health strategies should be developed. Providing psychosocial support and psychological guidance will contribute to mental health well-being, and improve the QOL and coping strategies.
Incidence and management of pneumothorax, pneumomediastinum, and subcutaneous emphysema in COVID-19
Authors: Abdelghany Youmna , Rachmasari Kharisa , Alvarez-Mulett Sergio , Wong Rochelle , Rajwani Kapil 
Published: September 2022

Objective: The coronavirus disease 2019 (COVID-19) pandemic reached New York City in March 2020, leading to a state of emergency that affected many lives. Patients who contracted the disease presented with different phenotypes. Multiple reports have described the findings of computed tomography scans of these patients, several with pneumothoraces, pneumomediastinum, and subcutaneous emphysema. Our aim was to describe the incidence and management of pneumothorax, pneumomediastinum, and subcutaneous emphysema related to COVID-19 found on radiologic imaging. Methods: A retrospective chart review was conducted of all confirmed COVID-19 patients admitted between early March and mid-May to two hospitals in New York City. Patient demographics, radiological imaging, and clinical courses were documented. Results: Between early March and mid-May, a total of 1866 patients were diagnosed with COVID-19 in the two hospitals included in the study, of which 386 were intubated. The majority of these patients were men (1090, 58.4%). The distribution of comorbidities included the following: hypertension (1006, 53.9%), diabetes (544, 29.6%), and underlying lung disease (376, 20.6%). Among the 386 intubated patients, 65 developed study-specific complications, for an overall incidence of 16.8%; 36 developed a pneumothorax, 2 developed pneumomediastinum, 1 had subcutaneous emphysema, and 26 had a combination of both. The mean time of invasive ventilation was 14 days (0–46, interquartile range = 6–19, median 11). The average of highest positive end expiratory pressure within 72 h of study complication was 11 (5–24) cmH20. The average of the highest peak inspiratory pressure within 72 h of complication was 35.3 (17–52) cmH2O. In non-Intubated patients, 9/1480 had spontaneous pneumothorax, for an overall incidence of 0.61 %. Conclusion: Intubated patients with COVID-19 pneumonia are at high risk of pneumothorax, pneumomediastinum, and subcutaneous emphysema. These should be considered in differential diagnosis of shortness of breath or hypoxia in a patient with a new diagnosis of COVID-19 or worsening hemodynamics or respiratory failure in an intensive care unit setting.
Clinical application of the Buffalo Concussion Treadmill Test and the Buffalo Concussion Bike Test: A systematic review
Authors: Janssen Ayden , Pope Rodney , Rando Natalie 
Published: September 2022

Objective To identify and synthesise research evidence regarding psychometric properties and clinical utility of the Buffalo Concussion Treadmill Test (BCTT) and Buffalo Concussion Bike Test (BCBT) for use with patients with acute concussion, post-concussion syndrome (PCS) or physiological post-concussion disorder (PPCD). Data sources ProQuest (ProQuest Central), PEDro, Medline (Ovid), Emcare (Ovid), EBSCOhost (Health collection) and Google Scholar, searched September 8th-12th, 2020. Study selection Two authors independently selected studies that met eligibility criteria. Studies were selected if they were original research of any design, that investigated the properties of the testing protocols in either concussed or uninjured participants. Articles not published in English, that were not original research or that used significantly different testing protocols were excluded. The search yielded 250 articles, 11 of which were eligible and included in this review. Data extraction Included studies were critically appraised independently by two authors, using the Mixed Methods Appraisal Tool (MMAT). Data relating to study characteristics and key findings were extracted from the studies, documented in tables, and used to inform a critical narrative synthesis of findings. Data synthesis To provide recommendations relating to each aim of the review, a strength of evidence scoring system was used. Available evidence supported use of the BCTT, with strong evidence supporting the safety and construct validity of the test and moderate evidence supporting its prognostic value. There has been very limited research investigating use of the BCBT. Conclusion The findings support a recommendation for use of the BCTT in clinical settings for management of acute concussion, PCS and PPCD. There is limited evidence available for the BCBT. Additional studies are needed of both tests to further establish their clinical value.
Hsa-microRNA-27b-3p inhibits hepatocellular carcinoma progression by inactivating transforming growth factor-activated kinase-binding protein 3/nuclear factor kappa B signalling
Authors: Wen Jingyuan , Huang Zhao , Wei Yi , Xue Lin , Wang Yufei , Liao Jingyu , Liang Junnan , Chen Xiaoping , Chu Liang , Zhang Bixiang 
Published: September 2022

Abstract
Background
MicroRNAs (miRNAs) play crucial roles in the development of hepatocellular carcinoma (HCC). Hsa-microRNA-27b-3p (hsa-miR-27b) is involved in the formation and progression of various cancers, but its role and clinical value in HCC remain unclear.

Methods
The expression of hsa-miR-27b in HCC was examined by quantitative real-time PCR (qRT-PCR) and in situ hybridization (ISH) assays of clinical samples. Cell Counting Kit-8 assays (CCK-8), 5-ethynyl-2′-deoxyuridine (EdU) incorporation assays, Transwell assays, filamentous actin (F-actin) staining and western blot analyses were used to determine the effects of hsa-miR-27b on HCC cells in vitro. Subcutaneous xenograft and lung metastatic animal experiments were conducted to verify the role of hsa-miR-27b in HCC in vivo. In silico prediction, qRT-PCR, western blot, anti-Argonaute 2 (AGO2) RNA immunoprecipitation (RIP) and dual luciferase reporter assays were applied to identify the target genes of hsa-miR-27b. To detect the impacts of hsa-miR-27b on nuclear factor kappa B (NF-кB) signalling cascades mediated by transforming growth factor-activated kinase-binding protein 3 (TAB3), we performed qRT-PCR, western blot assays, immunofluorescence staining, immunohistochemistry (IHC) and dual-luciferase reporter assays. Recombinant oncolytic adenovirus (OncoAd) overexpressing hsa-miR-27b was constructed to detect their therapeutic value in HCC.

Results
The expression of hsa-miR-27b was lower in HCC than in adjacent non-tumourous tissues (ANTs), and the reduced expression of hsa-miR-27b was associated with worse outcomes in patients with HCC. Hsa-miR-27b significantly inhibited the proliferation, migration, invasion, subcutaneous tumour growth and lung metastasis of HCC cells. The suppression of hsa-miR-27b promoted the nuclear translocation of NF-κB by upregulating TAB3 expression. TAB3 was highly expressed in HCC compared with ANTs and was negatively correlated with the expression of hsa-miR-27b. The impaired cell proliferation, migration and invasion by hsa-miR-27b overexpression were recovered by ectopic expression of TAB3. Recombinant OncoAd with overexpression of hsa-miR-27b induced anti-tumour activity compared with that induced by negative control (NC) OncoAd in vivo and in vitro.

Conclusions
By targeting TAB3, hsa-miR-27b acted as a tumour suppressor by inactivating the NF-кB pathway in HCC in vitro and in vivo, indicating its therapeutic value against HCC.

Graphical Abstract
Advertising of foods and beverages in social media aimed at children: high exposure and low control
Authors: Meléndez-Illanes Lorena , González-Díaz Cristina , Álvarez-Dardet Carlos 
Published: September 2022

Abstract
Background
This work is aimed to describe the recent scientific literature developed in the food/beverage sector and social networks aimed at children and adolescents, as well as current regulations.

Methods
A rapid review of the studies on advertising and social media aimed at children, published from 2010 tp 2020 is carried out, following the established inclusion criteria. In addition, the regulations in the countries in which the studies were carried out were also reviewed.

Results
Of the 573 articles, 7 met these criteria. The great attraction of unhealthy foods for children is observed, who remembered and recognized a greater number of unhealthy food brands and, by extension, the ability to influence of communication in social networks. Each country has its own self-regulation, two (Ireland and USA) have legislation on children’s food advertising, and Australia has legislation that applies only to open television. However, none of the analyzed countries have specific regulations on food, children and media advertising.

Conclusions
Given the fact that there is evidence about the great attraction that social networks suppose for the child, that they are a stimulus for the consumption of food and that many of these foods are harmful to their health; we should work in two directions: 1) Promote public policies based on promoting healthy habits among minors; and 2) Monitor and implement regulations in commercial communication social media.
The impact of COVID-19 on individual oral health: a scoping review
Authors: Dickson-Swift Virginia , Kangutkar Tejashree , Knevel Ron , Down Sarah 
Published: September 2022

AbstractBackgroundPoor oral health due to dental caries is one of the most prevalent non-communicable diseases worldwide. It has a significant impact on individuals across the lifespan and is a leading cause of preventable hospitalizations. The impacts of COVID-19 on oral health at the practice level are well documented, but gaps in understanding the impact on individual oral health remain. This review addresses this gap.MethodsUsing a JBI scoping review process we mapped and summarized the evidence to identify the impact of COVID-19 on individual oral health. Key search terms were developed, and searches were undertaken by an experienced research librarian.ResultsThe 85 included studies were conducted in 23 countries from 5 regions across the world classified using the United Nations Geoscheme system. The majority (82/85) were quantitative, 2 were reviews and there was one qualitative interview study. Cross-sectional surveys were the most common data collection approach followed by an analysis of clinical data, analysis of internet trends and other online methods. Five key areas were identified including changes to the provision of emergency dental services, provision of routine oral health services, oral hygiene maintenance at home, changes in dietary preferences, alternative models of dental provision and help-seeking and attitudes towards dental care in the future.ConclusionsThis scoping review has demonstrated that the pandemic has impacted on oral health at the individual level. It is important that we are aware of these impacts and ensure that support systems are in place to overcome future periods where access to dental care might be compromised. The provision of preventive care remains a vital first step in ensuring good overall oral health as is paramount during periods where access to dental treatment might be limited.
Development of the quality of teen trauma acute care patient and parent-reported experience measure
Authors: Yeung Matthew , Hagel Brent E. , Bobrovitz Niklas , Stelfox Thomas H. , Yanchar Natalie L. 
Published: September 2022

Abstract
Objective
Patient-Reported Experience Measures (PREMs) provide valuable patient feedback on quality of care and have been associated with clinical outcomes. We aimed to test the reliability of a modified adult trauma care PREM instrument delivered to adolescents admitted to hospital for traumatic injuries, and their parents. Modifications included addition of questions reflecting teen-focused constructs on education supports, social network maintenance and family accommodation.

Results
Forty adolescent patients and 40 parents participated. Test-retest reliability was assessed using Cohen’s kappa, weighted kappa, and percent agreement between responses. Directionality of changed responses was noted. Most of the study ran during the COVID-19 pandemic. We established good reliability of questions related to in-hospital and post-discharge communication, clinical and ancillary care and family accommodation. We identified poorer reliability among constructs reflecting experiences that varied from the norm during the pandemic, which included “maintenance of social networks”, “education supports”, “scheduling clinical follow-ups” and “post-discharge supports”. Parents, but not patients, demonstrated more directionality of change of responses by responding with more negative in-hospital and more positive post-discharge experiences over time between the test and retest periods, suggesting risk of recall bias. Situational factors due to the COVID-19 pandemic and potential risks of recall bias may have limited the reliability of some parts of the survey.
An initial investigation of accuracy required for the identification of small molecules in complex samples using quantum chemical calculated NMR chemical shifts
Authors: Yesiltepe Yasemin , Govind Niranjan , Metz Thomas O. , Renslow Ryan S. 
Published: September 2022

AbstractThe majority of primary and secondary metabolites in nature have yet to be identified, representing a major challenge for metabolomics studies that currently require reference libraries from analyses of authentic compounds. Using currently available analytical methods, complete chemical characterization of metabolomes is infeasible for both technical and economic reasons. For example, unambiguous identification of metabolites is limited by the availability of authentic chemical standards, which, for the majority of molecules, do not exist. Computationally predicted or calculated data are a viable solution to expand the currently limited metabolite reference libraries, if such methods are shown to be sufficiently accurate. For example, determining nuclear magnetic resonance (NMR) spectroscopy spectra in silico has shown promise in the identification and delineation of metabolite structures. Many researchers have been taking advantage of density functional theory (DFT), a computationally inexpensive yet reputable method for the prediction of carbon and proton NMR spectra of metabolites. However, such methods are expected to have some error in predicted 13C and 1H NMR spectra with respect to experimentally measured values. This leads us to the question–what accuracy is required in predicted 13C and 1H NMR chemical shifts for confident metabolite identification? Using the set of 11,716 small molecules found in the Human Metabolome Database (HMDB), we simulated both experimental and theoretical NMR chemical shift databases. We investigated the level of accuracy required for identification of metabolites in simulated pure and impure samples by matching predicted chemical shifts to experimental data. We found 90% or more of molecules in simulated pure samples can be successfully identified when errors of 1H and 13C chemical shifts in water are below 0.6 and 7.1 ppm, respectively, and below 0.5 and 4.6 ppm in chloroform solvation, respectively. In simulated complex mixtures, as the complexity of the mixture increased, greater accuracy of the calculated chemical shifts was required, as expected. However, if the number of molecules in the mixture is known, e.g., when NMR is combined with MS and sample complexity is low, the likelihood of confident molecular identification increased by 90%.
A novel secured Euclidean space points algorithm for blind spatial image watermarking
Authors: Basha Shaik Hedayath , B Jaison 
Published: September 2022

AbstractDigital raw images obtained from the data set of various organizations require authentication, copyright protection, and security with simple processing. New Euclidean space point’s algorithm is proposed to authenticate the images by embedding binary logos in the digital images in the spatial domain. Diffie–Hellman key exchange protocol is implemented along with the Euclidean space axioms to maintain security for the proposed work. The proposed watermarking methodology is tested on the standard set of raw grayscale and RGB color images. The watermarked images are sent in the email, WhatsApp, and Facebook and analyzed. Standard watermarking attacks are also applied to the watermarked images and analyzed. The finding shows that there are no image distortions in the communication medium of email and WhatsApp. But in the Facebook platform, raw images experience compression and observed exponential noise on the digital images. The authentication and copyright protection are tested from the processed Facebook images. It is found that the embedded logo could be recovered and seen with added noise distortions. So the proposed method offers authentication and security with compression attacks. Similarly, it is found that the proposed methodology is robust to JPEG compression, image tampering attacks like collage attack, image cropping, rotation, salt-and-pepper noise, sharpening filter, semi-robust to Gaussian filtering, and image resizing, and fragile to other geometrical attacks. The receiver operating characteristics (ROC) curve is drawn and found that the area under the curve is approximately equal to unity and restoration accuracy of [67 to 100]% for various attacks.
Chimeric antigen receptor T-cell therapy for relapsed and refractory thyroid cancer
Authors: Ding Jing , Li Deyu , Liu Xingchen , Hei Hu , Sun Baoxi , Zhou Dongmin , Zhou Keshu , Song Yongping 
Published: September 2022

AbstractThe prognosis of most thyroid cancer patients is excellent, but for those with advanced or metastatic thyroid cancer, effective treatments are still lacking. Chimeric antigen receptor (CAR) T-cell therapy has gained remarkable achievements in hematologic malignancy but shown limited efficacy in solid tumors. In this report, we showed a relapsed and refractory thyroid cancer patient treated with TSHR + CD19 CAR-T, a combination of two 2nd generation CAR-T molecules targeting both TSHR and CD19. This patient finally achieved partial remission at 3 months and was tolerate well to the regimen. Our study suggested that the CAR-T therapy could be a feasible way in treating relapsed and refractory thyroid cancer.
Investigating the effects of flipped vocabulary learning via an online dictionary on EFL learners' listening comprehension
Authors: Ebadi Saman , Nozari Fouzhan , Salman Ahmed Rawdhan 
Published: September 2022

AbstractThis study investigated the impact of flipped vocabulary learning on the listening achievement of EFL learners. The study participants included 60 English language learners selected based on their performance on the Michigan Test of English Language Proficiency and randomly assigned to experimental and control groups. The experimental group was taught based on flipped vocabulary learning, while the students in the control group received no such instruction. For treatment in the experimental group, the teacher taught the unknown and new vocabulary in the listening text from the TACTICS textbook using an online dictionary to flip the classroom. The teacher offered an online dictionary and encouraged learners to check out words, synonyms, and antonyms to become more familiar with new words. Before each listening class, students memorized 20 target words, prior to taking on the listening tasks. The obtained data were analyzed using the ANCOVA procedure. The study results demonstrated that the experimental group performed significantly better than the control group. Also, the findings suggested that flipped vocabulary learning can be used as an effective instructional tool to help learners improve their listening achievement. The theoretical and practical implications for learners, teachers, and syllabus designers are discussed.