bluuebunny/crossref_metadata_2025_split huggingface dataset:
A 30‐year systematic review reveals success in tephritid fruit fly biological control research
Authors: Dias Naymã Pinto , Montoya Pablo , Nava Dori Edson 
Published: February 2022

AbstractFruit flies (Diptera: Tephritidae) are among the main pests in horticulture, impacting field crops and export markets. The biological control of fruit flies has become an important method for environmentally friendly crop production. Although biological control is an age‐old practice and the mass‐rearing of some biological agents boomed in the 1990s, efforts in fruit fly control programs still face several challenges. We conducted a systematic review to investigate publications assessing the success or failure of using natural enemies against tephritid fruit flies. Our goal was to compile and summarize information from over 30 years of research on biocontrol efforts, including groups and species of control agents and fruit flies tested, methodological approaches applied, the country where the study was performed, and the scope adopted. We also analyzed effectiveness, efficiency, and success rates in biocontrol studies published from 1990 to 2021. Our review showed 2986 records, of which 225 publications matched the criteria. The most‐studied biocontrol agents for the suppression of fruit flies were parasitoids, fungi, and nematodes. A few studies assessed bacteria, predators, and viruses. We found a total of 55 fruit fly species described as hosts of the biological agents. Natural/conservation biological control was the main scope studied; however, augmentative biological control had a higher rate of successful studies and potential success, followed by classical biological control. The effectiveness and efficiency parameters are discussed to provide support for researchers in future studies.
The introduced oak Quercus rubra and acorn‐associated arthropods in Europe: An opportunity for both carpophagous insects and their ant predators
Authors: Giannetti Daniele , Schifani Enrico , Castracani Cristina , Spotti Fiorenza Augusta , Mori Alessandra , Grasso Donato Antonio 
Published: February 2022

Abstract
We studied the interactions involving oak acorns and associated arthropods focusing on the role of the introduced Quercus rubra in Italy.
We conducted our study in areas where native oaks coexist with Q. rubra. We carried out a survey on the arthropods inhabiting fallen acorns and a colonisation experiment. Furthermore, we conducted laboratory experiments documenting the interactions among the most abundant arthropod species on Q. rubra.
Acorns were colonised by ant species and carpophagous insects showing different preferences concerning acorns' position within the leaf litter and oak species. Acorns of Q. rubra were colonised frequently by ants (mostly Temnothorax nylanderi) and Cydia fagiglandana. Cydia splendana preferred native acorns, while Curculio beetles were ubiquitous. Our data suggest that ants occupy exclusively acorns previously attacked by Cydia, killing or displacing their caterpillars if still developing inside the acorns. Vertebrates may prefer to feed on Q. rubra acorns over native species.
Quercus rubra has a meaningful influence on native arthropods associated with oak acorns. The ecological consequences of this interaction are still not fully clear, yet our data suggest an increase in acorn‐consuming insects, partly affecting the acorns of neighbouring native oaks, but also an increase of predatory ants.
Students' resilience and mental health in the dental curriculum
Authors: Maragha Tala , Donnelly Leeann , Schuetz Christian , von Bergmann HsingChi , Brondani Mario 
Published: February 2022

AbstractObjectivesDental education is perceived as a source of students’ psychological and occupational stress. Resilience has been proposed as a protective factor that may support students’ in managing that stress. The objectives of this study were twofold: to map the mental health and well‐being content in the curriculum of the Faculty of Dentistry (FoD) at the University of British Columbia (UBC) and to investigate factors influencing resilience levels amongst dental students at UBC.MethodsThe curricular database and website of UBC's FoD were used to gather information on mental health content. A survey with the Connor‐Davidson 10‐Item Resilience Scale was distributed to dental students at UBC (N = 289). Students' de‐identified demographic data were also collected.ResultsTwo main mental health and well‐being curricular components were identified: one didactic session on stress management and one interactive workshop on resilience. The response rate for the survey was 68.2%. Students who did not receive any mental health content (2020/21 year 1 students) had higher resilience scores (p = .043) when compared to students who received both components (2019/20 year 1 students and 2018/19 year 2 students). The multiple regression analysis highlighted North American/European ethnic origins as a predictor for higher resilience levels (p = .008).ConclusionsThe results of this study showed that ethnic origins and major life events, such as the pandemic, influenced resilience. Curricular activities promoting resilience seemed to not necessarily impact students' resilience. Further longitudinal studies are needed to assess the curricular and non‐curricular activities influence over dental students' well‐being.
“Middle‐aged Old Mothers” in China: Childrearing Anxiety, Humor, and the Narrative Self
Authors: Xu Jing 
Published: February 2022

AbstractWith the rise of hyper education in contemporary China, the phrase “middle‐aged old mother” has become an important narrative identity for mothers over 30 in the urban middle class. Based on ethnographic and virtual fieldwork from 2018 to 2020, this paper weaves together interviews, observation, and social media data to examine mothers’ moral experience of childrearing anxiety in Beijing. This article goes beyond the surface content of “middle‐aged old mother” narratives and instead highlights the narrative context, style, intention, and effect. It aims to understand their first‐person narratives of parenting characterized by heightened uncertainty, high stakes, self‐reflexivity, and gender inequalities. The “middle‐aged old mother” script provides a template for and becomes the “co‐author” of Chinese mothers’ auto‐narratives: It blends self‐mockery, personal story, and social critique in an environment of intensifying competition and moral quandaries. The term is a deliberate act of humor and an invitation for empathy.
The impact of mobile demersal fishing on carbon storage in seabed sediments
Authors: Epstein Graham , Middelburg Jack J. , Hawkins Julie P. , Norris Catrin R. , Roberts Callum M. 
Published: February 2022

AbstractSubtidal marine sediments are one of the planet's primary carbon stores and strongly influence the oceanic sink for atmospheric CO2. By far the most widespread human activity occurring on the seabed is bottom trawling/dredging for fish and shellfish. A global first‐order estimate suggested mobile demersal fishing activities may cause 0.16–0.4 Gt of organic carbon (OC) to be remineralized annually from seabed sediment carbon stores (Sala et al., 2021). There are, however, many uncertainties in this calculation. Here, we discuss the potential drivers of change in seabed sediment OC stores due to mobile demersal fishing activities and conduct a literature review, synthesizing studies where this interaction has been directly investigated. Under certain environmental settings, we hypothesize that mobile demersal fishing would reduce OC in seabed stores due to lower production of flora and fauna, the loss of fine flocculent material, increased sediment resuspension, mixing and transport and increased oxygen exposure. Reductions would be offset to varying extents by reduced faunal bioturbation and community respiration, increased off‐shelf transport and increases in primary production from the resuspension of nutrients. Studies which directly investigated the impact of demersal fishing on OC stocks had mixed results. A finding of no significant effect was reported in 61% of 49 investigations; 29% reported lower OC due to fishing activities, with 10% reporting higher OC. In relation to remineralization rates within the seabed, four investigations reported that demersal fishing activities decreased remineralization, with three reporting higher remineralization rates. Patterns in the environmental and experimental characteristics between different outcomes were largely indistinct. More evidence is urgently needed to accurately quantify the impact of anthropogenic physical disturbance on seabed carbon in different environmental settings and to incorporate full evidence‐based carbon considerations into global seabed management.
Patients' experiences across the trajectory of atrial fibrillation: A qualitative systematic review
Authors: Wang Jie , Liu Shenxinyu , Bao Zhipeng , Gao Min , Peng Yuanyuan , Huang Yangxi , Yu Tianxi , Wang Lin , Sun Guozhen 
Published: February 2022

AbstractAimThis study aimed to synthesize qualitative evidence on experiences of patients with atrial fibrillation (AF) during the course of diagnosis and treatment. We addressed three main questions: (a) What were the experiences of patients with AF during the course of diagnosis and treatment? (b) How did they respond to and cope with the disease? (c) What were the requirements during disease management?DesignIn this study, qualitative evidence synthesis was performed using the Thomas and Harden method.Data SourcesElectronic databases, including PubMed, the Cochrane Library, Embase, Web of Science, Cumulative Index to Nursing and Allied Health Literature, the China Biomedical Database, the WanFang Database, Chinese National Knowledge Infrastructure and VIP, were searched. The databases were searched from inception to August 2021.Review MethodsTwo researchers independently selected studies using qualitative assessment and review instruments for quality evaluation and thematic synthesis for the data analysis.ResultsA total of 2627 studies were identified in the initial search and 15 studies were included. Five analytical themes were generated: ‘Diagnosing AF’; ‘The impact of AF on the patients’; ‘Self‐reorientation in the therapeutic process’; ‘Living with AF and QoL’; and ‘External support to facilitate coping strategies.’ConclusionsOur findings point out unique experiences of patients across the trajectory of AF related to delayed diagnosis, feelings of nonsupport, disappointment of repeated treatment failure and multiple distress associated with unpredictable symptoms. Future research and clinical practice are expected to improve the quality of medical diagnosis and treatment, optimize administrative strategy and provide diverse health support for patients with AF.ImpactUnderstanding the experiences and needs of patients with AF in the entire disease process will inform future clinical practice in AF integrated management, which would be helpful in improving the professionalism and confidence of healthcare providers. In addition, our findings have implications for improving the effectiveness of AF diagnostic and treatment services.Patient or Public ContributionThis paper presents a review of previous studies and did not involve patients or the public.
Conservation biogeography of high‐altitude longhorn beetles under climate change
Authors: Poloni Riccardo , Iannella Mattia , Fusco Giuseppe , Fattorini Simone 
Published: February 2022

Abstract
High‐altitude insects are expected to be strongly affected by climate change because of their limited range. Phytophagous species will be subject to further threats because of their dependence on host plants.
We investigated the impact of climate change on the distribution of Italian high‐altitude longhorn beetles (Cerambycidae) using a maximum entropy approach based on bioclimatic variables. We used 510 presence records for 15 species distributed throughout the Italian Alps and Apennines. Then, we combined climate‐based predictions with vegetation data to predict the future changes in the extent of suitable areas.
All species but two will move uphill to track suitable climates and will face a range contraction (with an average loss of 44%) under both climatic change scenarios considered. Suitable vegetation covers, on average, only 56% of the estimated current species ranges, which means that the future distribution will be even more limited. Given the importance of Italian mountains as hubs of diversity in the Mediterranean hotspot, these results are particularly alarming.
Conservation actions that can mitigate the effects of climate change on high‐altitude cerambycids should be focused on contrasting habitat loss and degradation through land preservation and the adoption of appropriate forest management practices.
EXPECTATIONS, STAGNATION, AND FISCAL POLICY: A NONLINEAR ANALYSIS
Authors: Evans George W. , Honkapohja Seppo , Mitra Kaushik 
Published: February 2022

AbstractStagnation and fiscal policy are examined in a nonlinear stochastic New‐Keynesian model with adaptive learning. There are three steady states. The steady state targeted by policy is locally but not globally stable under learning. A severe pessimistic expectations shock can trap the economy in a stagnation regime, underpinned by a low‐level steady state, with falling inflation and output. A large fiscal stimulus may be needed to avoid or emerge from stagnation, and the impacts of forward guidance, credit frictions, central bank credibility, and policy delay are studied. Our model encompasses a wide range of outcomes arising from pessimistic expectations shocks.
Gluten‐free cakes with walnut flour: a technological, sensory, and microstructural approach
Authors: Burbano Juan José , Cabezas Darío Marcelino , Correa María Jimena 
Published: February 2022

SummaryWalnut flour (WF), a by‐product of walnut oil production, is characterised by high polyunsaturated fatty acids, proteins, and fibre contents and presents suitability for bakery products. However, when using non‐traditional ingredients, it is essential to evaluate the effect on the quality properties of the final product. So, this work aimed to assess the impact of WF on the technological, physicochemical, and sensory properties of gluten‐free (GF) cakes. WF was added at a flour blend (cassava (CS) and maize (MS) starches and rice flour) at 0, 10%, 15%, and 20%. The results showed that WF modified starch gelatinisation, increased amylose–lipid complex (ALC) content, and made crumbs easier to chew. Besides, the total dietary fibre (TDF) and protein content significantly increased. Cakes with 15% WF presented the highest specific volume (SV) and no differences in overall acceptability with respect to control. Hence, WF is a suitable ingredient for gluten‐free bakery products.
Proximate analysis, nutritional quality and anti‐amylase activity of bee propolis, bee bread and royal jelly
Authors: Fallah Masoomeh , Najafi Fatemeh , Kavoosi Gholamreza 
Published: February 2022

SummaryThis study discussed the proximate composition, nutritional properties, amino acid profile and anti‐amylase activity of royal jelly, propolis and bee bread. Royal jelly, bee bread and propolis have lower protein and lipid and more sugar than soybeans and eggs. Soybeans have the highest energy, followed by bee bread, propolis, royal jelly and eggs. Eggs have the highest protein digestibility, followed by royal jelly, bee bread, soybeans and propolis. The primary amino acids in bee bread, royal jelly and propolis are proline, glycine, lysine, alanine, aspartic acid, serine, glutamic acid, threonine, arginine, leucine, tyrosine, phenylalanine, histidine, β‐aminobutyric acid, valine, asparagine and methionine. Amino acids from royal jelly, propolis and bee bread inhibited amylase by increasing Km/Vmax and decreasing Vmax and Km through un‐competitive or non‐competitive strategies. Molecular docking, ultraviolet absorption and fluorescence quenching analysis showed that amino acids interact with amylase structure at the allosteric site through van der Waals interactions and hydrogen bonds. Bee products can be used as food supplements, ingredients and medications to manage diabetes by inhibiting amylase.
Genetic and phylogenetic characterization of Shiga toxin-producing Escherichia coli and enteropathogenic E. coli from livestock in Jiangsu by using whole-genome sequencing
Authors: Han Yue , Liu Minqi , Han Ying , Shi Naiyang , Wang Qiang , Cui Tingting , Yang Liuqing , Zhang Xuefeng , Zhu Liguo , Qian Huimin , Jin Hui , Dong Chen 
Published: February 2022

Abstract

Aims
There are knowledge gaps regarding STEC and EPEC strains in livestock in Jiangsu, China. This study aimed to evaluate the potential public health significance of STEC and EPEC strains isolated from livestock by determining the serotypes, virulence profiles, and genetic relationship with international STEC strains.

Methods and Results
A total of 68 STEC and 37 EPEC strains were obtained from 231 faecal sheep samples and 70 faecal cattle samples. By using whole-genome sequencing (WGS) analysis, all STEC belonged to 15 O: H serotypes, and the most prevalent serotypes were O6:H10 (19.1%), O155:H21 (14.7%), and O21:H25 (10.3%). The main Shiga toxin gene subtypes detected were stx1c (41.2%), stx1a (26.5%), stx2b (14.7%), and stx2k (14.7%). Only the STEC from cattle carried eae gene. Other adherence-associated or toxin-related genes, including lpfA (70.6%), iha (48.5%), subA (54.4%), and ehxA (33.8%), were found in STEC. All EPEC strains were bfpA-negative, and the predominant eae variants were eae-β1 (62.2%), eae-ζ (21.6%), and eae-θ (8.1%). The core-genome multi-locus sequence typing (cgMLST) analysis revealed nine scattered clusters in STEC and one dominant cluster in EPEC. The strains with the same serotypes, including O22:H8 and O43:H2 in the two towns, possessed a closely genomic distance. The core genome single-nucleotide polymorphism (cgSNP) showed that part of STEC strains in this study was clustered with isolates possessing the same serotypes from the Netherlands, Sweden, and Xinjiang of China. Five serotypes of STEC isolates were associated with the clinical STEC strains from databases.

Conclusion
This study provided the diverse serotypes and the virulence genes profiles in STEC and EPEC strains. Local strains possessed widely diverse and scattered clusters by cgMLST. Closely genomic correlation with clinical isolates displayed that part of the STEC strains may threaten to public health.

Significance and Impact of the Study
Non-O157 STEC strains act as important pathogens for human infections. This study supports the increased surveillance work of non-O157 STEC rather than just O157 STEC in this region.
A prospective cohort study on the association of lean body mass estimated by mid‐upper arm muscle circumference with hypertension risk in Chinese residents
Authors: Liu Yuyan , Sun Guifan , Li Yongfang 
Published: February 2022

AbstractThe associations of lean body mass (LBM) with elevated blood pressure (BP) and hypertension were controversial, and the causalities have never been shown. Mid‐upper arm muscle circumference (MAMC), an easily obtained anthropometric measurement, could provide an accurate estimate for LBM. Therefore, a prospective cohort study in general Chinese residents aiming to find out the relationship between LBM estimated using MAMC and hypertension risk was performed. Eight thousand one hundred eighty‐five eligible participants were included in the baseline analysis, among whom 3442 were subsequently selected into cohort analysis. MAMC was calculated using mid‐upper arm circumference (MUAC) and triceps skinfold thickness (TST). Associations of MAMC with BP values and hypertension prevalence were estimated by linear and logistic regression models. Associations with hypertension incidence were estimated by COX regression models, hazard ratio (HR) and 95% confidence interval (CI) were given. Nonlinear relationship between MAMC and hypertension risk was estimated using restricted cubic spline method. Standardized coefficients of MUAC and TST were compared to estimate their strengths of associations with hypertension. Baseline analysis showed that after adjusted for confounders, the increase of systolic BP per standard deviation (SD) of MAMC were 1.97 mmHg (95%CI: 1.46, 2.48) and 1.63 mmHg (95%CI: 1.10, 2.16) respectively in men and women, and the increases of diastolic BP per SD were 1.58 mmHg (95%CI: 1.23, 1.92) and 1.08 mmHg (95%CI: 0.74, 1.42). Additionally, the association of MAMC with the prevalence of hypertension were also found in both men and women (OR = 1.36, 95%CI: 1.26, 1.47 in men; OR = 1.33, 95%CI: 1.22, 1.44 in women). Cohort analysis showed that MAMC increased the risk of hypertension (HR = 1.10, 95%CI: 1.01, 1.19 for men; HR = 1.15, 95%CI: 1.06, 1.26 for women), and a trend of J‐shaped relationship was found. Additionally, the stronger associations of MUAC with both BP values and hypertension than that of TST were found in both baseline and cohort analyses. Findings in our study implied that we cannot neglect the capacity of LBM in predicting hypertension risk, and LBM estimates should be recommended in general health surveys or examinations.
BMAL1 regulates mitochondrial homeostasis in renal ischaemia‐reperfusion injury by mediating the SIRT1/PGC‐1α axis
Authors: Ye Peng , Li Wei , Huang Xin , Zhao Sheng , Chen Wu , Xia Yuqi , Yu Weimin , Rao Ting , Ning Jinzhuo , Zhou Xiangjun , Ruan Yuan , Cheng Fan 
Published: February 2022

AbstractThe regulation of renal function by circadian gene BMAL1 has been recently recognized; however, the role and mechanism of BMAL1 in renal ischaemia‐reperfusion injury (IRI) are still unknown. The purpose of this study was to clarify the pathophysiological role of BMAL1 in renal IRI. We measured the levels of BMAL1 and mitochondrial biogenesis‐related proteins, including SIRT1, PGC‐1α, NRF1 and TFAM, in rats with renal IRI. In rats, the level of BMAL1 decreased significantly, resulting in inhibition of SIRT1 expression and mitochondrial biogenesis. In addition, under hypoxia and reoxygenation (H/R) stimulation, BMAL1 knockdown decreased the level of SIRT1 and exacerbated the degree of mitochondrial damage and apoptosis. Overexpression of BMAL1 alleviated H/R‐induced injury. Furthermore, application of the SIRT1 inhibitor EX527 not only reduced the activities of SIRT1 and PGC‐1α but also further aggravated mitochondrial dysfunction and partially reversed the protective effect of BMAL1 overexpression. Moreover, whether in vivo or in vitro, the application of SIRT1 agonist resveratrol rescued the mitochondrial dysfunction caused by H/R or IRI by activating mitochondrial biogenesis. These results indicate that BMAL1 is a key circadian gene that mediates mitochondrial homeostasis in renal IRI through the SIRT1/PGC‐1α axis, which provides a new direction for targeted therapy for renal IRI.