bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deep Learning for Cancer Symptoms Monitoring on the Basis of Electronic Health Record Unstructured Clinical Notes
Authors: Lindvall Charlotta , Deng Chih-Ying , Agaronnik Nicole D. , Kwok Anne , Samineni Soujanya , Umeton Renato , Mackie-Jenkins Warren , Kehl Kenneth L. , Tulsky James A. , Enzinger Andrea C. 
Published: June 2022

PURPOSE Symptoms are vital outcomes for cancer clinical trials, observational research, and population-level surveillance. Patient-reported outcomes (PROs) are valuable for monitoring symptoms, yet there are many challenges to collecting PROs at scale. We sought to develop, test, and externally validate a deep learning model to extract symptoms from unstructured clinical notes in the electronic health record. METHODS We randomly selected 1,225 outpatient progress notes from among patients treated at the Dana-Farber Cancer Institute between January 2016 and December 2019 and used 1,125 notes as our training/validation data set and 100 notes as our test data set. We evaluated the performance of 10 deep learning models for detecting 80 symptoms included in the National Cancer Institute's Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE) framework. Model performance as compared with manual chart abstraction was assessed using standard metrics, and the highest performer was externally validated on a sample of 100 physician notes from a different clinical context. RESULTS In our training and test data sets, 75 of the 80 candidate symptoms were identified. The ELECTRA-small model had the highest performance for symptom identification at the token level (ie, at the individual symptom level), with an F1 of 0.87 and a processing time of 3.95 seconds per note. For the 10 most common symptoms in the test data set, the F1 score ranged from 0.98 for anxious to 0.86 for fatigue. For external validation of the same symptoms, the note-level performance ranged from F1 = 0.97 for diarrhea and dizziness to F1 = 0.73 for swelling. CONCLUSION Training a deep learning model to identify a wide range of electronic health record–documented symptoms relevant to cancer care is feasible. This approach could be used at the health system scale to complement to electronic PROs.
Telecommuting Pedagogies
Authors: Hong Renyi 
Published: June 2022

AbstractThis article examines the early telecommuting discourse of the 1980s and 1990s, understanding it as a pedagogical context for white plasticity, an ecological project in which racial privilege is protected through the transformation of homes and inhabitants. Rationalized initially as a crisis of adjustment, pedagogies of telecommuting were disseminated largely to upper-middle-class white professionals to build a “telecommuting personality,” a subjectivity that was also meant to buffer them from the growing precarious nature of jobs. Not content to focus simply on work, however, telecommuting gurus took occasion to urge the enhancement of relationships between partners, families, and communities. The home office was core to this imaginary. Convertible, modular, ergonomic home offices that can be changed to suit the needs of the home's many inhabitants were said to yield more integrated and rounded personalities that would radiate outward, creating emotionally mature children and stronger community bonds. Emerging at a moment when “telecommuting” condensed the political stakes of digital labor, this strand of discourse reveals how working from home was appropriated to ensure the protection of white plasticity—the racialized capability of adaptation that was to be passed as inheritance from parents to progeny.
Debility, Negative Affect, Mobility
Authors: Sánchez Cruz Jorge 
Published: June 2022

Abstract
This article proposes that the undocumented as a valence of difference expands on queer studies’ turn to a subjectless critique and how debility and negativity become part of the discussion of an objectless critique. In examining Alan Pelaez Lopez's “sick in ‘america,’” Julio Salgado's oeuvre, and Yosimar Reyes's #UndocuJoy, it is argued that undocumented queer subjects living under a landscape of debility and a climate of negative affect diagnose contemporary tactics of debility deployed as frames of illegality, securitization, and biopoliticization, and simultaneously reflect how the production of negative affect leads to feelings of nonbelonging, of being off. This article goes on to suggest that debility is conjoined to negative affect, arguing that in spite a continual state of debility and a dispersion of negativity, the undocumented thrive in the practices of the everyday, presented here as another lens of thinking mobility, a recalibrator to the debility/capacity/(dis)ability imaginary.
Mobilizing Stories of Illness in Digital Contexts: A Critical Approach to Narrative, Voice, and Visibility
Authors: Giaxoglou Korina 
Published: June 2022

AbstractIllness stories have been celebrated as a resource for giving patients voice from the active position of the wounded storyteller. The proliferating research on illness stories, however, has often reproduced a reductionist approach to narrative as a window to subjective views and experiences based on a largely underdeveloped and essentialized notion of voice. Critics of the over-celebration of narrative have called for caution toward the use of personal stories, pointing to the need to situate constructions of the narrative self in their social, cultural, and political contexts. This article discusses a new type of illness stories that has emerged in digital contexts and that is characterized by the use of illness for producing various forms of economic and social value. Using small stories and affective positioning as its analytic lens, the article examines the specific case of story design, curation, and sharing of the COVID-19 diagnosis of actor Idris Elba in March 2020. As the article argues, the illness experience is mobilized in small stories online as a resource for authenticating the self in line with conventional modes of sharing, blurring the lines between the personal voice and the public visibility of storytelling. The article contributes to the critical study of the mobilization of stories in digital contexts.
Intersex Surgery between the Gaze and the Subject
Authors: Morland Iain 
Published: June 2022

AbstractThis essay critiques the practice of childhood genital surgery for intersex/disorders of sex development. The essay draws on the sociology of perception and poststructuralist theory (in particular Jacques Lacan) to analyze the subject position offered by surgery as a function of the impersonal gaze that precedes subjectivity. Even though early surgery appears to be justified on the basis that children have an innate need to see sexual difference in order to identify as female or male, this argument in favor of surgery collapses when we recognize that sexual difference is not a thing that can be seen by any individual but a spacing between bodies that is apparent only to the gaze. The essay suggests additionally that intersex studies can collaborate with trans* studies to interrogate medicalization and consider sexual difference as multidimensional rather than binary.
Intersex's New Materialism
Authors: Goss Katie 
Published: June 2022

Abstract
Intersex thinkers and activists, queer-feminist science studies, and new materialist initiatives have argued that sex's complex materiality undermines the rigid binaries imposed by essentialist biology and exceeds the malleability of the body constructed as entirely open to intervention and control in biopower. Through a close reading of Lucia Puenzo's XXY, and the realist depiction of the impasses and rich potentialities surrounding intersex embodiment it puts forth, this article explores how intersex becomes the locus for expansive ontoepistemological schemas. Suffused with a rich visual language foregrounding the subject's plastic arts and the collective bodies of the ecosystem, XXY situates the expansive significance of intersex not only as an integral and intelligible form of bio-logical embodiment but also as a generative and even generalizable mode of more-than-binary corporeality.
SAIBR: a simple, platform-independent method for spectral autofluorescence correction
Authors: Rodrigues Nelio T. L. , Bland Tom , Borrego-Pinto Joana , Ng KangBo , Hirani Nisha , Gu Ying , Foo Sherman , Goehring Nathan W. 
Published: June 2022

ABSTRACT
Biological systems are increasingly viewed through a quantitative lens that demands accurate measures of gene expression and local protein concentrations. CRISPR/Cas9 gene tagging has enabled increased use of fluorescence to monitor proteins at or near endogenous levels under native regulatory control. However, owing to typically lower expression levels, experiments using endogenously tagged genes run into limits imposed by autofluorescence (AF). AF is often a particular challenge in wavelengths occupied by commonly used fluorescent proteins (GFP, mNeonGreen). Stimulated by our work in C. elegans, we describe and validate Spectral Autofluorescence Image Correction By Regression (SAIBR), a simple platform-independent protocol and FIJI plug-in to correct for autofluorescence using standard filter sets and illumination conditions. Validated for use in C. elegans embryos, starfish oocytes and fission yeast, SAIBR is ideal for samples with a single dominant AF source; it achieves accurate quantitation of fluorophore signal, and enables reliable detection and quantification of even weakly expressed proteins. Thus, SAIBR provides a highly accessible low-barrier way to incorporate AF correction as standard for researchers working on a broad variety of cell and developmental systems.
Breaking Sitting Time with Physical Activity Increases Energy Expenditure but Does Not Alter Postprandial Metabolism in Girls
Authors: SMALLCOMBE JAMES W. , BIDDLE GREGORY J. H. , SLATER TOMMY , THACKRAY ALICE E. , DUNSTAN DAVID W. , BARRETT LAURA A. , TOLFREY KEITH 
Published: June 2022

ABSTRACT

Purpose
Young people spend a substantial proportion of their time at school sedentary; therefore, this setting represents an important target for interventions aimed at displacing sedentary time with physical activity. This study aimed to examine the postprandial metabolic effects of breaking sedentary time by accumulating walking and repeated bouts of nonambulatory standing during simulated school days in inactive adolescent girls.

Methods
Seventeen girls (mean ± SD = 12.8 ± 0.4 yr) completed two 3-d experimental conditions. On days 1 and 2 of the standing + walking (STD-WLK) experimental trial, participants interrupted sedentary time by completing 4 × 10 min bouts of self-paced walking and accumulated 18 × 5 min standing bouts during each simulated school day. On day 3 of STD-WLK, participants attended school as normal with no additional physical activity or standing prescribed. On all 3 d of the control condition (CON), participants attended school as normal with no physical activity intervention. On days 2 and 3 of both STD-WLK and CON, a baseline capillary blood sample was provided to determine fasting [TAG] and [glucose]. Participants then consumed a standardized breakfast (0 h) and lunch (4.7 h), and blood samples were provided postprandially at 2.7, 5.3, and 7.3 h for [TAG] and [glucose].

Results
Energy expenditure was 28% (95% confidence interval = 8% to 52%) higher during school hours on day 1 and day 2 during STD-WLK compared with CON (2171 vs 1693 kJ; effect size = 0.89, P = 0.008). However, no reduction of fasting or postprandial [TAG] or [glucose] was observed on day 2 or day 3 (P ≥ 0.245).

Conclusions
Two consecutive days of breaking prolonged sitting with self-paced walking and intermittent standing had no meaningful effect on postprandial metabolism in adolescent girls.
Intellectual disability in the children of the Avon Longitudinal Study of Parents and Children (ALSPAC)
Authors: Madley-Dowd Paul , Thomas Richard , Boyd Andy , Zammit Stanley , Heron Jon , Rai Dheeraj 
Published: June 2022

Background: Intellectual disability (ID) describes a neurodevelopmental condition involving impaired cognitive and functional ability. Here, we describe a multisource variable of ID using data from the Avon Longitudinal Study of Parents and Children (ALSPAC). Methods: The multisource indicator variable for ID was derived from i) IQ scores less than 70 measured at age 8 and at age 15, ii) free text fields from parent reported questionnaires, iii) school reported provision of educational services for individuals with a statement of special educational needs for cognitive impairments, iv) from relevant READ codes contained in GP records, iv) international classification of disease diagnoses contained in electronic hospital records and hospital episode statistics and v) recorded interactions with mental health services for ID contained within the mental health services data set. A case of ID was identified if two or more sources indicated ID. A second indicator, labelled as “probable ID”, was created by relaxing the cut off in IQ scores to be less than 85. An indicator variable for known causes of ID was also created to aid in aetiological studies where ID with a known cause may need to be excluded. Results: 158 of 14,370 participants (1.10%) were indicated as having ID by two or more sources and 449 (3.12%) were indicated as having probable ID when the criteria for IQ scores was relaxed to less than 85. There were 476 participants (3.31%) with 1 or fewer sources of available information on ID; these participants had their multisource variable set to missing. The number of cases of ID with known cause was 31 (0.22%). Conclusions: The multisource variable of ID can be used in future analyses on ID in ALSPAC children.
Wide range linear magnetometer based on a sub-microsized K vapor cell
Authors: Auzinsh M. , Sargsyan A. , Tonoyan A. , Leroy C. , Momier R. , Sarkisyan D. , Papoyan A. 
Published: June 2022

39

K

atoms have the smallest ground state (

2

S

1

/

2

) hyperfine splitting of all the most naturally abundant alkali isotopes and, consequently, the smallest characteristic magnetic field value

B
0

=

A

2

S

1

/

2

/

μ
B

≈
170

G

, where

A

2

S

1

/

2

is the ground state’s magnetic dipole interaction constant. In the hyperfine Paschen–Back regime (

B

≫

B
0

, where

B

is the magnitude of the external magnetic field applied on the atoms), only eight Zeeman transitions are visible in the absorption spectrum of the

D
1

line of

39

K

, while the probabilities of the remaining 16 Zeeman transitions tend to zero. In the case of

39

K

, this behavior is reached already at relatively low magnetic field

B

>

B
0

. For each circular polarization (

σ
−

,

σ
+

), four spectrally resolved atomic transitions having sub-Doppler widths are recorded using a sub-microsized vapor cell of thickness

L
=
120

−

390

n
m

. We present a method that allows to measure the magnetic field in the range of

0.1

−

10

k
G

with micrometer spatial resolution, which is relevant in particular for the determination of magnetic fields with large gradients (up to 3 G/µm). The theoretical model describes well the experimental results.
Complex “zero-shot” super-resolution reconstruction algorithm for THz imaging
Authors: Wang Ying , Qi Feng , Wang Jinkuan 
Published: June 2022

To deal with a terahertz (THz) super-resolution (SR) algorithm based on a convolutional neural network (CNN) without standard training datasets, a complex “zero-shot” SR (CZSSR) reconstruction algorithm is proposed according to the internal image statistics with a five-layer complex CNN model. Instead of relying on pre-training, the proposed method is of sound self-adaptability. Compared with real ZSSR, the peak SNR of CZSSR rose by about 0.94 dB, MSE decreased by 0.042, and SSIM increased by about 40% for the SR result of the measured data. The results show that the CZSSR method can solve the low-resolution problem of a THz imaging system and the shortage of datasets in THz SR based on CNN. Therefore, this research is of great significance for application in the fields of medical imaging and non-destructive detection.
Feasibility of a multifaceted intervention to improve treatment initiation among patients diagnosed with TB using Xpert MTB/RIF testing in Uganda
Authors: Zawedde-Muyanja Stella , Musaazi Joseph , Castelnuovo Barbara , Cattamanchi Adithya , Katamba Achilles , Manabe Yukari C. 
Published: June 2022

Background
One in five patients diagnosed with TB in Uganda are not initiated on TB treatment within two weeks of diagnosis. We evaluated a multifaceted intervention for improving TB treatment initiation among patients diagnosed with TB using Xpert® MTB/RIF testing in Uganda.

Methods
This was a pre-post interventional study at one tertiary referral hospital. The intervention was informed by the COM-B model and included; i) medical education sessions to improve healthcare worker knowledge about the magnitude and consequences of pretreatment loss to follow-up; ii) modified laboratory request forms to improve recording of patient contact information; and iii) re-designed workflow processes to improve timeliness of sputum testing and results dissemination. TB diagnostic process and outcome data were collected and compared from the period before (June to August 2019) and after (October to December 2019) intervention initiation.

Results
In September 2019, four CME sessions were held at the hospital and were attended by 58 healthcare workers. During the study period, 1242 patients were evaluated by Xpert® MTB/RIF testing at the hospital (679 pre and 557 post intervention). Median turnaround time for sputum test results improved from 12 hours (IQR 4–46) in the pre-intervention period to 4 hours (IQR 3–6) in the post-intervention period. The proportion of patients started on treatment within two weeks of diagnosis improved from 59% (40/68) to 89% (49/55) (difference 30%, 95% CI 14%-43%, p<0.01) while the proportion of patients receiving a same-day diagnosis increased from 7.4% (5/68) to 25% (14/55) (difference 17.6%, 95% CI 3.9%-32.7%, p<0.01).

Conclusion
The multifaceted intervention was feasible and resulted in a higher proportion of patients initiating TB treatment within two weeks of diagnosis.
Monitoring sustainable development goal 5.2: Cross-country cross-time invariance of measures for intimate partner violence
Authors: Yount Kathryn M. , Bergenfeld Irina , Mhamud Nishat , Clark Cari Jo , Kaslow Nadine J. , Cheong Yuk Fai 
Published: June 2022

BackgroundThe persistence and impacts of violence against women motivated Sustainable Development Goal (SDG) 5.2 to end such violence. Global psychometric assessment of cross-country, cross-time invariance of items measuring intimate partner violence (IPV) is needed to confirm their utility for comparing and monitoring national trends.MethodsAnalyses of seven physical-IPV items included 377,500 ever-partnered women across 20 countries (44 Demographic and Health Surveys (DHS)). Analyses of five controlling-behaviors items included 371,846 women across 19 countries (42 DHS). We performed multiple-group confirmatory factor analysis (MGCFA) to assess within-country, cross-time invariance of each item set. Pooled analyses tested cross-country, cross-time invariance using DHSs that showed configural invariance in country-level multiple-group confirmatory factor analysis (MGCFAs). Alignment optimization tested approximate invariance of each item set in the pooled sample of all datasets, and in the subset of countries showing metric invariance over at least two repeated cross-sectional surveys in country-level MGCFAs.ResultsIn country-level MGCFAs, physical-IPV items and controlling-behaviors items functioned equivalently in repeated survey administrations in 12 and 11 countries, respectively. In MGCFA testing cross-country, cross-time invariance in pooled samples, neither item set was strictly equivalent; however, the physical-IPV items were approximately invariant. Controlling-behaviors items did not show approximate cross-country and cross-time invariance in the full sample or the sub-sample showing country-level metric invariance.ConclusionPhysical-IPV items approached approximate invariance across 20 countries and were approximately invariant in 11 countries with repeated cross-sectional surveys. Controlling-behaviors items were cross-time invariant within 11 countries but did not show cross-country, cross-time approximate invariance. Currently, the physical-IPV item set is more robust for monitoring progress toward SDG5.2.1, to end IPV against women.
Psychosocial functioning of adolescents with ADHD in the family, school and peer group: A scoping review protocol
Authors: Karteczka-Świętek Kinga , Opozda-Suder Sylwia , Strojny Agnieszka 
Published: June 2022

Objective
The objective of this scoping review is to investigate what is known about the psychosocial functioning of adolescents with ADHD. All basic life environments (family, school and peer group) will be considered.

Introduction
Adolescence is especially critical for people with ADHD–natural maturation may be accompanied by changing symptoms of ADHD. A number of childhood difficulties transform during adolescence and contribute to problems in various areas that comprise psychosocial functioning. The available studies focus on selected domains of psychosocial functioning of adolescents with ADHD, however, to the authors’ best knowledge, there is no comprehensive description of this issue. The lack of such a description is the main rationale for conducting this scoping review.

Inclusion criteria
Pointing to the PCC elements (population, concept, context), the scoping review will include primary studies on the concept of psychosocial functioning (including functioning in the family, school and peer group). In the included studies, the term "psychosocial functioning" (or related) had to be used explicitly. The population will be adolescents (10 to 19 years old) with a formal diagnosis of ADHD (DSM classification) or Hyperkinetic Syndrome (ICD-9) or Hyperkinetic Disorders (ICD-10). There will be no restrictions on the research context.

Methods
The methodology of scoping reviews will be applied in accordance with the guidelines of the Joanna Briggs Institute (JBI). The following databases: Academic Search Ultimate, ERIC, MEDLINE, ProQuest Central, PsycInfo, Scopus, and databases under the Web of Science will be searched for primary studies in peer-reviewed journals, written in English and published since 1987. The analyses will be based mainly on frequency counts of the components of psychosocial functioning and population characteristics. The results will be presented in tabular form and supplemented with a descriptive summary. The protocol has been registered on the Open Science Framework: https://doi.org/10.17605/OSF.IO/MS82H [registration DOI].