bluuebunny/crossref_metadata_2025_split huggingface dataset:
Politics of Islam in Javanese Aesthetics: R. Ng. Yasadipura I’s Poe(li)tical Imagination of Islam in Babad Tanah Jawi
Authors: Fawaid Achmad , Udasmoro Wening , Margana Sri , Hussen Bannaga Taha Al-Zubair 
Published: July 2022

This paper is to figure out R. Ng. Yasadipura I’s poe(li)tical imagination of Islam in Babad Tanah Jawi. The ‘politics’ is defined not merely as instrumental utility, but intertwined with ‘poetics’, an aesthetic strategy which allegorically unveils an interpretation of the undecidability of Islam as central Islam or peripheral Islam, as Arabia Islam or Javanese Islam. Based on the biographical and structural approaches, this article attempts to analyze textual, ideological, and religious traces of this 18th century Javanese Muslim bhujangga and its relation to the way he describes Islam in Babad Tanah Jawi. Yasadipura I is a political subject, since he describes Islam not merely as a religious consensus, but also dissensus to other identities. This dissensus is partly a logical consequence of—using Jacques Rancière’s term—Yasadipura I’s ‘class migration’, ranging from Muslim student (santri) from Kedu, royal advisor (menteri) of Surakarta court, to prolific writer and translator of Hindu-Buddhist kakawin and Islamic Malay suluk.
Experiences and attitudes of parents of children with cow’s milk and other food-allergy
Authors: Karakurt Tuba , Bekis Bozkurt Hayrunnisa , Kaplan Fatih , Akşit Anıl , Cavkaytar Özlem , Topal Erdem , Arga Mustafa 
Published: July 2022

Introduction and objective: The attitude and behaviors of parents are important in the management of children with food allergy (FA). The aim of this study is to evaluate the experiences and attitudes of parents of children with allergy to cow’s milk and other FA.
Materials and methods: The parents of children with FA were asked to complete an 18-item questionnaire to evaluate the FA history and experiences during diagnosis, treatment, and follow up.
Results: The data from 558 (91.2%) survey questionnaire that were filled completely were analyzed. The mean age of the parents was 33.4+4.9. It was found that most common food allergen was cow’s milk (85.3%). The mean time to diagnosis from the onset of symptoms was 10.9±18.4 months. Around 229 parents (41.6%) admitted to at least four different physicians and 68 (12.3%) parents admitted to at least five different physicians before diagnosis. The median time to diagnosis from the onset of symptoms was five (1-108) months in the patients admitted to four or more physicians, but it was one (1-48) month in the patients that admitted to less physicians (p˂0.001). The most common symptoms were dermatitis and mucus-bloody stool, the least common ones were cardiovascular symptoms. Only 21.1% of the patients were able to use hypoallergenic formulas (HAF) in accordance with the recommendation of the physician.
Conclusions: Delayed diagnosis of FA is a major concern, and during this period the patients admit many physicians. A majority of the patients with CMPA experience difficulties while using HAFs, and only one-fifth of them is able to use formula regularly.
RAB11A aggravates PDGF-BB-stimulated proliferation, migration, and inflammation of airway smooth muscle cells via affecting the NF-κB and PI3K/AKT pathways
Authors: Gong Ying , Hu Yunhai , Huang Jianqiong , Wang Haibo 
Published: July 2022

Background: Pediatric asthma is an usual disease and a kind of fearful health threat for children. Airway smooth muscle cells (ASMCs) with increased cell proliferation and migration abilities serve as important features in the progression of asthma. RAB11A has been shown to aggravate cancer progression and is closely associated with inflammation. Gene analysis discovered that RAB11A exhibited higher expression in asthmatic patients. However, the detailed regulatory function of RAB11A in asthma still needs further investigation.
Method: The mRNA and protein expressions of genes were examined through RT-qPCR and western blot. Cell proliferation was examined through MTT and BrdU assays. Cell apoptosis was tested through flow cytometry. The cell migration ability was detected through wound healing and transwell assays. The levels of TNF-α, IL-1β, IL-8, and IL-6 were measured through ELISA.
Result: In this study, the mRNA and protein expressions of RAB11A were increased with PDGF-BB treatment in a dose-dependent manner. Additionally, the silencing of RAB11A suppressed the proliferation ability of PDGF-BB-mediated ASMCs. Moreover, it was uncovered that the knockdown of RAB11A inhibited the migration ability of PDGF-BB-stimulated ASMCs. Besides, suppression of RAB11A relieved the inflammatory response in PDGF-BB-stimulated ASMCs. Lastly, inhibition of RAB11A retarded the NF-κB and PI3K/AKT pathways.
Conclusion: Our results revealed that RAB11A aggravated PDGF-BB-stimulated proliferation, migration, and inflammation of ASMCs through modulating NF-κB and PI3K/AKT signaling pathways. This finding implied that the RAB11A may be deemed as a novel and prospective biomarker for asthma treatment.
Engaging 'Respect for Persons' in Music Therapy
Authors: Lauzon Paul Laurent 
Published: July 2022

The goal of this article is to bring clarity to the notion of ‘respect for persons’ and to outline possible applications for the clinical music therapist. An argument is made that we can build understanding about respect for persons by raising a series of pertinent questions, beginning with, 1) How does a clinical Code of Ethics deal with respect for persons? 2) What do I mean when I call someone a ‘Person’? 3) What are key issues concerning personhood? 4) What do we mean when we ‘respect a person’? 5) What are some implications of ‘respect for persons’ in clinical music therapy? and importantly, 6) How do I understand respect from the client’s point of view?
The Relationship between Cerebrovascular Reactivity and Cerebral Oxygenation during Hemodialysis
Authors: Richerson Wesley T. , Schmit Brian D. , Wolfgram Dawn F. 
Published: July 2022

Significance Statement
Patients with ESKD have a high burden of ischemic brain lesions related to decline in cerebral blood flow during hemodialysis. Preliminary studies in patients on hemodialysis noted impairment in cerebrovascular reactivity, a mechanism that regulates cerebral perfusion. We found that lower cerebrovascular reactivity was associated with greater decrease in cerebral oxygen saturation during hemodialysis, particularly when accounting for changes in systemic BP. These results suggest that testing cerebrovascular reactivity could be relevant to characterizing risk of cerebral ischemia during hemodialysis and the potential sequelae of brain injury and cognitive impairment over time.

Background
Patients with kidney failure treated with hemodialysis (HD) may be at risk for cerebral hypoperfusion due to HD-induced BP decline in the setting of impaired cerebral autoregulation. Cerebrovascular reactivity (CVR), the cerebrovascular response to vasoactive stimuli, may be a useful indicator of cerebral autoregulation in the HD population and identify those at risk for cerebral hypoperfusion. We hypothesize that CVR combined with intradialytic BP changes will be associated with declines in cerebral oxygenation saturation (ScO2) during HD.

Methods
Participants completed the MRI scans on a non-HD day and cerebral oximetry during HD. We measured CVR with resting-state fMRI (rs-fMRI) without a gas challenge and ScO2 saturation with near-infrared spectroscopy. Regression analysis was used to examine the relationship between intradialytic cerebral oxygen desaturation, intradialytic BP, and CVR in different gray matter regions.

Results
Twenty-six patients on HD had complete data for analysis. Sixteen patients were men, 18 had diabetes, and 20 had hypertension. Mean±SD age was 65.3±7.2 years, and mean±SD duration on HD was 11.5±9.4 months. CVR in the anterior cingulate gyrus (ACG; P=0.03, r2
=0.19) and insular cortex (IC; P=0.03, r2
=0.19) regions negatively correlated with decline in intradialytic ScO2. Model prediction of intradialytic ScO2 improved when including intradialytic BP change and ultrafiltration rate to the ACG rsCVR (P<0.01, r2
=0.48) and IC rsCVR (P=0.02, r2
=0.35) models, respectively.

Conclusions
We found significant relationships between regional rsCVR measured in the brain and decline in intradialytic ScO2. Our results warrant further exploration of using CVR in determining a patient’s risk of cerebral ischemic injury during HD.
Improved access to rapid electroencephalography at a community hospital reduces inter‐hospital transfers for suspected non‐convulsive seizures
Authors: Madill Evan Samuel , Gururangan Kapil , Krishnamohan Prashanth 
Published: July 2022

AbstractObjective. Patients with suspected non‐convulsive seizures are optimally evaluated with EEG. However, limited EEG infrastructure at community hospitals often necessitates transfer for long‐term EEG monitoring (LTM). Novel point‐of‐care EEG systems could expedite management of nonconvulsive seizures and reduce unnecessary transfers. We aimed to describe the impact of rapid access to EEG using a novel EEG device with remote expert interpretation (tele‐EEG) on rates of transfer for LTM.Methods. We retrospectively identified a cohort of patients who underwent Rapid‐EEG (Ceribell Inc., Mountain View, CA) monitoring as part of a new standard‐of‐care at a community hospital. Rapid‐EEGs were initially reviewed on‐site by a community hospital neurologist before transitioning to tele‐EEG review by epileptologists at an affiliated academic hospital. We compared the rate of transfer for LTM after Rapid‐EEG/tele‐EEG implementation to the expected rate if rapid access to EEG was unavailable.Results. Seventy‐four patients underwent a total of 118 Rapid‐EEG studies (10 with seizure, 18 with highly epileptiform patterns, 90 with slow/normal activity). Eighty‐one studies (69%), including 9 of 10 studies that detected seizures, occurred after‐hours when EEG was previously unavailable. Based on historical practice patterns, we estimated that Rapid‐EEG potentially obviated transfer for LTM in 31 of 33 patients (94%); both completed transfers occurred before the transition to tele‐EEG review.Significance. Rapid access to EEG led to the detection of seizures that would otherwise have been missed and reduced inter‐hospital transfers for LTM. We estimate that the reduction in inter‐hospital transportation costs alone would be in excess of $39,000 ($1,274 per patient). Point‐of‐care EEG systems may support a hub‐and‐spoke model for managing non‐convulsive seizures (similar to that utilized in this study and analogous to existing acute stroke infrastructures), with increased EEG capacity at community hospitals and tele‐EEG interpretation by specialists at academic hospitals that can accept transfers for LTM.
First reported case of an inheritedPACS2pathogenic variant with variable expression
Authors: Cesaroni Elisabetta , Matricardi Sara , Cappanera Silvia , Marini Carla 
Published: July 2022

AbstractNeonatal epilepsy, cerebellar dysgenesis and facial dysmorphisms may be associated withde novo PACS2missense pathogenic variants (EIEE 66) (OMIM #618067). Here, we report a toddler boy with neonatal‐onset seizures, developmental delay with hypotonia, facial dysmorphisms and prominence of the cisterna magna, mild inferior vermian and cerebellar hypoplasia. A nextgeneration epilepsy gene panel revealed a known pathogenicPACS2missense variant, p.Glu209Lys, that was inherited from his mildly affected mother. We describe the firstPACS2pathogenic variant to be inherited, expanding the clinical spectrum, associated with a mild phenotype in the mother and a more severe phenotype in her son, in keeping with previously reported descriptions.
Epilepsy with myoclonic absences: a case series highlighting clinical heterogeneity and surgical management
Authors: Carter Emma G. , Armour Eric A. , Pagano Lindsay M. , Reddy Shilpa B. 
Published: July 2022

AbstractObjective. Epilepsy with myoclonic absences is a rare epilepsy syndrome with distinct features and high rates of drug resistance. Identifying this syndrome may help guide treatment decisions. We highlight clinical heterogeneity in this case series and two cases in which corpus callosotomy was performed.Methods. Medical records were reviewed between 2017 and 2021 to identify demographics, comorbidities, age at onset, EEG findings, diagnostic evaluations, seizure semiologies, seizure frequency, anti‐seizure medications, diet therapy and surgical treatments in patients with myoclonic absences.Results. Ten patients were identified including twins with myoclonic absence status epilepticus. Forty percent had an atonic component, 20% presented with myoclonic absence status epilepticus and 60% had incomplete control of seizures at last follow‐up visit. Two patients with epilepsy with myoclonic absences with atonia underwent corpus callosotomy; one patient was seizurefree eight months after surgery and the other had greater than 50% seizure reduction over a five‐month period.Significance. Phenotypic heterogeneity was evident based on seizure semiologies, comorbidities, seizure frequency and response to anti‐seizure medications and non‐medication treatments. Of patients with an atonic component, 75% did not achieve seizure freedom with medication alone. Corpus callosotomy was performed in two of these patients with encouraging seizure response thus far, however, the efficacy of this treatment should be further evaluated in a larger study.
Trisomy 20p/monosomy 18p associated with congenital bilateral perisylvian syndrome
Authors: Bonardi Claudia M. , Bayat Allan , Madsen Camilla G⊘bel , Hammer Trine B. , Reale Chiara , Gardella Elena , Marjanovic Dragan , Beniczky Sandor , M⊘ller Rikke S. , Rubboli Guido 
Published: July 2022

AbstractWe report the association, not previously described, between trisomy 20/ monosomy 18 and congenital bilateral perisylvian syndrome (CBPS), a condition featuring intellectual disability, epilepsy, oro‐motor dysfunction and bilateral perisylvian polymicrogyria (BPP) in a 29‐year‐old individual. Detailed clinical evaluation, long‐term EEG and EEG analysis by means of electrical source imaging (ESI), 3T MRI and array‐CGH were performed. Clinical examination showed moderate/severe intellectual disability, dysmorphic features, oro‐motor dysfunction, short stature, abnormal hands and feet, bradykinesia and abnormal posture. The patient had suffered from drug‐resistant epilepsy since infancy. Brain MRI showed that BPP was consistent with CBPS. Additional imaging features revealed corpus callosum and cerebellar hypoplasia and fusion of the C1‐C2 vertebrae. Ictal EEG and ESI documented tonic seizures originating from the right polymicrogyric cortex. Facial gestalt included dysmorphic features reported in patients with 18‐ and 20+ chromosomal rearrangements. Array‐CGH showed an unbalanced translocation, arr(18p)x1(20p)x3. In conclusion, we provide a detailed electro‐clinical and MRI description of a novel condition characterized by the association between trisomy 20p/monosomy 18p and CBPS, also illustrating its clinical evolution into adulthood. This information may help paediatricians, neurologists and geneticists to better counsel families about the developmental prognosis of this rare unbalanced chromosomal rearrangement.
Autoeficacia, procrastinación y rendimiento académico en estudiantes universitarios de Ecuador
Authors: Zumárraga-Espinoza Marcos , Cevallos-Pozo Gabriela 
Published: July 2022

El estudio de los factores no cognitivos que influyen en el éxito académico se ha posicionado como un tópico de creciente interés para la investigación educativa. En este marco, este estudio se propone el objetivo de examinar la relación entre el rendimiento académico universitario y dos factores no cognitivos específicos: la autoeficacia y la procrastinación académica. De igual manera, se explora el rol mediador que la procrastinación académica desempeña en la relación entre la autoeficacia y el rendimiento académico. El estudio cuantitativo se realizó en el contexto ecuatoriano y se basó en una muestra conformada por 788 estudiantes matriculados en universidades públicas y privadas del Distrito Metropolitano de Quito. La estrategia analítica consistió en la formulación de modelos de ruta, fundamentados en la metodología de ecuaciones estructurales. Los principales resultados del análisis empírico son los siguientes: a) tanto la autoeficacia como la procrastinación académica afectan directamente el desempeño académico de los estudiantes universitarios; b) la autoeficacia se relaciona indirectamente en el rendimiento académico a través de la procrastinación académica; c) estos factores no cognitivos son más determinantes para el desempeño estudiantil en la etapa inicial de carrera, especialmente en el caso de universidades privadas. Finalmente se discuten las implicaciones de los hallazgos efectuados, considerando el desarrollo potencial de estrategias de promoción del éxito académico mediante intervenciones que favorezcan el sentido de autoeficacia y la autorregulación del estudiantado.
Efektivitas Model Sinektik terhadap Kemampuan Menulis Karangan: Tinjauan pada Aspek Kreativitas Siswa SD
Authors: Mulyadiprana Ahmad , Nur Lutfi 
Published: July 2022

Abstract This study aims to develop a synectic learning model in teaching Indonesian language to the development of elementary school student creativity. The classroom action research method was carried out on 16 grade V elementary school students. Data collection was obtained through SPM test instruments (standard progressive matrices), essay assessment and field notes. The results showed that the synectic learning model contributed to the development of elementary school student creativity. This finding is expected to be an alternative for teachers in optimizing educational attainment. Future studies can be tested on other subjects and control groups are added as a comparison. Abstrak Penelitian ini bertujuan mengembangkan model pembelajaran sinektik dalam pengajaran bahasa Indonesia terhadap pengembangan kreativitas siswa sekolah dasar. Metode penelitian tindakan kelas dilakukan terhadap 16 siswa sekolah dasar kelas V. Pengumpulan data diperoleh melalui Instrumen tes SPM (standar progressive matrices), penilaian karangan dan catatan lapangan. Hasil penelitian menunjukkan bahwa model pembelajaran sinektik memberikan kontribusi terhadap pengembangan kreativitas siswa sekolah dasar. Temuan ini diharapkan menjadi alternative para guru dalam mengoptimalkan pencapaian pendidikan. Penelitian selanjutnya dapat diujicobakan pada mata pelajaran lainnya serta ditambahkan kelompok control sebagai pembanding.
BioIntegrada Game Application: An Instrument for the Systemic Teaching from Cells to the Environment
Authors: Medeiros Vaneria Maria Pinheiro , Silveira Andréa Pereira 
Published: July 2022

Background: Biology contents in high school are worked in a fragmented way, and in excessively theoretical and expositive classes, but game apps appear as tools with high playful potential. Objective: To identify the contributions of BioIntegrada in the construction of the integrative perception of the contents of the cell and the environment. Design: Qualitative approach and action research method. Setting and participants: 40 students enrolled in the 2nd grade of high school at a state public school in the municipality of Milhã, Ceará, Brazil. Data collection and analysis: We used audio recordings and questionnaires with closed and open items and analysed the textual information with the Iramuteq software. Results: BioIntegrada is composed of eight phases, addressing issues of cellular structure, tissues, organs, human body systems, the cycle of worms, scales of ecological organisation and daily actions. By validating the app, we found that the students improved their theoretical knowledge and argumentative level, starting to relate abiotic and biotic factors with the constitution of living beings and deepening socio-environmental discussions of the web of humans and nature relationships. Furthermore, the students evaluated the app positively; 95% liked using it and considered it a facilitator of learning; 85% agreed that it is intuitive and its phases are stimulating. Conclusion: BioIntegrada facilitated learning contents, promoted the integrated perception of the human body and the environment, and was evaluated as good by the students.
Cultura de innovación de la docencia en Instituciones Universitarias. Transformaciones ante las circunstancias de la Covid-19. Desarrollo de competencias
Authors: Medina Rivilla Antonio 
Published: July 2022

La investigación de la Innovación de la docencia, que presentamos tiene como finalidad, en coherencia con la pretendida por el equipo, presidido por la Drª Domínguez Garrido, construir una visión de mejora integral de las prácticas de enseñanza en la Universidad, en coherencia con el reto del COVID-19 y le etapa de incertidumbre emergida.
Se ha pretendido formar a docentes y estudiantes, especialmente de primero de Universidad y Master en la formación de competencias profesionales y genéricas, mediante el diseño de actividades y utilidad de TIC, coherentes con tal desafío, empleando el foro de la plataforma ALF.
La Metodología aplicada se ha focalizado en el estudio de caso, completado con el análisis de contenido de los textos correspondientes a las respuestas dadas a las diversas tareas, coherentes con el avance en las competencias de Identidad, Innovadora y Metodológico, para capacitar a los estudiantes mediante procesos de aprendizaje activo, empleando el Programa Atlas-ti y el contraste entre expertos.
Los análisis evidencian le implicación de los estudiantes en el acto formativo y el uso de la plataforma, como recurso de apoyo, que permite sintetizar las abundantes respuestas y proceder al estudio minucioso de las mismas.
Se destaca la colaboración y el rigor de las actuaciones y la calidad de lo realizado, conscientes del papel creativo de cada estudiante, díadas y la asesoría del profesorado participante.
Se destaca el avance en la formación en las competencias de Identidad, Comunicación y Metodológica, que han configurado las claves de una nueva cultura Universitaria, en coherencia con los objetivos planteados.
Se señala la comunidad de indagación y transferencia, que se ha conformado entre profesorado y estudiantes y los logros en la formación en las competencias pretendidas, en el periodo de pandemia con prioridad en las de Identidad y comunicación.
Se confirma la dedicación del profesorado y la pertinencia de las tareas propuestas a cada estudiante en el periodo del COVID-19, que han consolidado esta cultura de Innovación de la docencia y la formación en las competencias pretendidas de los estudiantes, con apoyo del foro.