bluuebunny/crossref_metadata_2025_split huggingface dataset:
Auditory brainstem implantation in children: the case of place of articulation
Authors: Odijk Lotte , Faes Jolien 
Published: November 2022

This study aimed to investigate the development of the production of place of articulation of three children with auditory brainstem implants (ABI) in spontaneous speech production. The main participants were three children implanted with an ABI. They were compared against two different control groups: children with a cochlear implant (CI) and children with normal hearing (NH). Data was obtained fromspontaneous speech between the children and their caregivers. For each word production, the place of articulation of both the target word as the child’s own production was identified. This was broadly identified in three categories: labial, coronal and dorsal. The analysis revealed that in general, the coronal place of articulation was most used in all children’s own production, as well as in the target words, except for one child with ABI, who showed a preference for labials. In terms of accuracy, labial place of articulation was produced more accurately than the coronal place of articulation for all children. The dorsal place of articulation had very low accuracy probabilities. Children with ABI had the lowest accuracy rates. When the place of articulation was not correctly produced, they were often omitted instead of replaced by another place of articulation. It was concluded that the children with ABI benefit from their device, but still have a long way to go to catch up to their peers. It is suggested that sign language is needed to guarantee smooth communication.
Keywords: auditory brainstem implantation; pediatric; oral language, place of articulation;labial; coronal; dorsal
Dutch Norming Study For 208 Color Drawings Depicting Transitive Events
Authors: Sijyeniyo Edwige , Hartsuiker Robert J. , Bernolet Sarah 
Published: November 2022

We conducted a norming study amongst Dutch children (6-12 years) to investigate whether they would correctly interpret our set of 208 color drawings, developed for longitudinal research on the production and comprehension of transitive sentences, if the transitive action on each drawing was described with an active or a passive sentence. The children provided 93.02% correct answers to our pictures, which indicates that the pictures are clear in terms of how the transitive actions are displayed. There were several factors that contributed to an incorrect interpretation of a transitive action in a picture. (1) Pictures were more difficult to interpret when a passive sentence was used to describe a transitive event compared to an active sentence; (2) children made more errors interpreting pictures when abstract verbs, such as “inhalen” (to overtake) and “vervangen” (to replace), were used to describe a transitive event; (3) children had difficulty interpreting our pictures when particular verbs (“roepen” [to shout] and “volgen” [to follow]) were presented in a passive sentence, while other verbs (“blokkeren” [to block] and “inhalen”) rendered more correct answers when the transitive event was described with a passive sentence; finally, (4) younger children provided more incorrect answers to our pictures than older children, regardless of whether the transitive action in the picture was described with an active or a passive sentence. In particular, the younger children provided significantly more incorrect answers to pictures with the verb “groeten” (to greet) compared to the older children. Because our set contains many verb-noun combinations, the set is very useful to researchers who intend to investigate the acquisition of transitive structures in children in a longitudinal design, not only for studies with typically developing children, but also in studies with children who have a delay in their language development. Keywords: Norming study, picture set, transitive structures, L1 syntax acquisition.
The Association Between Clinical Severity and Incubation Period of SARS-CoV-2 Delta Variants: Retrospective Observational Study
Authors: Wang Kai , Luan Zemin , Guo Zihao , Ran Jinjun , Tian Maozai , Zhao Shi 
Published: November 2022

Background
As of August 25, 2021, Jiangsu province experienced the largest COVID-19 outbreak in eastern China that was seeded by SARS-CoV-2 Delta variants. As one of the key epidemiological parameters characterizing the transmission dynamics of COVID-19, the incubation period plays an essential role in informing public health measures for epidemic control. The incubation period of COVID-19 could vary by different age, sex, disease severity, and study settings. However, the impacts of these factors on the incubation period of Delta variants remains uninvestigated.

Objective
The objective of this study is to characterize the incubation period of the Delta variant using detailed contact tracing data. The effects of age, sex, and disease severity on the incubation period were investigated by multivariate regression analysis and subgroup analysis.

Methods
We extracted contact tracing data of 353 laboratory-confirmed cases of SARS-CoV-2 Delta variants’ infection in Jiangsu province, China, from July to August 2021. The distribution of incubation period of Delta variants was estimated by using likelihood-based approach with adjustment for interval-censored observations. The effects of age, sex, and disease severity on the incubation period were expiated by using multivariate logistic regression model with interval censoring.

Results
The mean incubation period of the Delta variant was estimated at 6.64 days (95% credible interval: 6.27-7.00). We found that female cases and cases with severe symptoms had relatively longer mean incubation periods than male cases and those with nonsevere symptoms, respectively. One-day increase in the incubation period of Delta variants was associated with a weak decrease in the probability of having severe illness with an adjusted odds ratio of 0.88 (95% credible interval: 0.71-1.07).

Conclusions
In this study, the incubation period was found to vary across different levels of sex, age, and disease severity of COVID-19. These findings provide additional information on the incubation period of Delta variants and highlight the importance of continuing surveillance and monitoring of the epidemiological characteristics of emerging SARS-CoV-2 variants as they evolve.
N-end rule-mediated proteasomal degradation of ATGL promotes lipid storage
Authors: Xu Jiesi , Liu Zhenglong , Zhang Jianxin , Chen Siyu , Wang Wei , Zhao Xuefan , Zhen Mei , Huang Xun 
Published: November 2022

<p>Cellular lipid storage is regulated by the balance of lipogenesis and lipolysis. The rate-limiting triglyceride hydrolase ATGL (desnutrin/PNPLA2) is critical for lipolysis. The control of ATGL transcription, localization and activation has been intensively studied, while regulation of the protein stability of ATGL is much less explored. Here we showed that the protein stability of ATGL is regulated by the N-end rule in cultured cells and in mice. The N-end rule E3 ligases UBR1 and UBR2 reduce the level of ATGL and affect lipid storage. The N-end rule-resistant ATGL(F2A) mutant, in which the N-terminal phenylalanine (F) of ATGL is substituted by alanine (A), has increased protein stability and enhanced lipolysis activity. <em>ATGLF2A/F2A</em> knock-in mice are protected against high-fat diet (HFD)-induced obesity, hepatic steatosis and insulin resistance. Hepatic knockdown of <em>Ubr1</em> attenuates HFD-induced hepatic steatosis by enhancing the ATGL level. Finally, the protein levels of UBR1 and ATGL are negatively correlated in the adipose tissue of obese mice. Our study reveals N-end rule-mediated proteasomal regulation of ATGL, a finding which may potentially be beneficial for treatment of obesity.</p>
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Analisis Pertukaran Barang-Barang Ribawi Pada Pedagang Pasar (Studi Kasus Pasar Tamiang)
Authors: Nasution Edi Marjan 
Published: November 2022

This research was conducted at Tamiang Market, Kotanopan District, focusing on the exchange of usury goods by local market participants. This study uses a qualitative descriptive nature, namely research directed at providing symptoms, facts, or events systematically and accurately regarding the characteristics of a particular population or area. This method also uses qualitative descriptive properties to use qualitative descriptive properties to research directly involved in the field/community or a place that is used as the object of study (Tamuang Market). At the same time, the data collection uses interview observations and documentation. The problem in this research is that street vendors and market visitors always exchange ribawi goods (gold for gold and rice for rice) after the big harvest; this exchange is done because traders and market visitors have a brotherly relationship, and this is considered normal. The study results show that this exchange is carried out because it has become a cost ('urf) because both the merchant and the seller have a family relationship whose transaction is consensual. Keywords: usury ribawi’s, exchange, market
PELAKSANAAN LAPORAN PERTANGGUNGJAWABAN BANTUAN KEUANGAN PARTAI POLITIK DI KOTA PEKANBARU BERDASARKAN PERATURAN PEMERINTAH NOMOR 5 TAHUN 2009 TENTANG BANTUAN KEUANGAN KEPADA PARTAI POLITIK
Authors: Ratnasari Siska , Syahril Ardiansah , Syam Aliar 
Published: November 2022

Regulasi mengatur bahwa partai politik wajib menyampaikan laporan pertanggungjawaban penerimaan dan pengeluaran keuangan yang bersumber dari dana bantuan APBN/APBD secara berkala 1 (satu) tahun sekali kepada Pemerintah setelah diperiksa oleh Badan Pemeriksa Keuangan (BPK), namun di Kota Pekanbaru pelaksanaanya belum berjalan sebagaimana mestinya karena keterlambatan penyampaian laporan yang dimaksud yang berimbas terhadap perencanaan kinerja dan realisasi pencairan dana bantuan tersebut. Penelitian bertujuan menganalisis pelaksanaan laporan pertanggungjawaban bantuan keuangan partai politik di Kota Pekanbaru, merumuskan faktor – faktor penghambatnya serta menemukan upaya – upaya untuk mengatasinya. Jenis penelitian yang digunakan adalah adalah penelitian hukum sosiologis/ empiris melalui pendekatan perundang – undangan dengan metode analisis kualitatif. Hasil penelitian diketahui bahwa faktor penghambat penyampaian laporan oleh partai politik adalah regulasi yang belum mengatur sanksi keterlambatan dan pergantian pengurus partai politik, lembaga eksekutif dan legislatif yang sejauh ini belum bisa dipisahkan antara kepentingan pribadi dan kepentingannya sebagai penyelenggara pemerintahan, Keterbatasan anggaran yang diberikan kepada Badan Kesatuan Bangsa dan Politik Kota Pekanbaru serta beberapa faktor internal partai politik .Upaya yang perlu dilakukan adalah revisi regulasi, memperkuat fungsi check and balance penyelenggaraan pemerintahan antara legislatif dan eksekutif, menaikkan anggaran Badan Kestuan Bangsa dan Politik Kota Pekanbaru serta mengadakan Bimtek mengenai pengelolaan bantuan keuangan dan penyusunan laporan bantuan keuangan partai politik.
KAJIAN YURIDIS PERATURAN MENTERI HUKUM DAN HAK ASASI MANUSIA NOMOR 10 TAHUN 2020 DALAM UPAYA PENCEGAHAN DAN PENANGGULANGAN PENYEBARAN COVID-19 SERTA MENGURANGI OVERCROWDED WARGA BINAAN DI LAPAS RUTAN WILAYAH JAWA TIMUR
Authors: Sushanty Vera Rimbawani 
Published: November 2022

AbstrakPeraturan Menteri Hukum dan Hak Asasi Manusia Nomor 10 Tahun 2020 adalah kebijakan pemerintah dalam melakukan pencegahan dan penanggulangan penyebaran Covid-19 yang terjadi di dalam Lembaga Pemasyarakatan dan Rumah Tahanan Negara. Penelitian ini dilaksanakan untuk mengetahui Implementasi Peraturan Menteri Hukum dan Hak Asasi Manusia Nomor 10 Tahun 2020 dan menganalisa pengaruh Peraturan Menteri tersebut terhadap Jumlah Warga Binaan di Lapas Rutan Wilayah Jawa Timur. Metode Penelitian yang digunakan dalam penelitian ini adalah metode penelitian Hukum Normatif yang mengacu pada peraturan perundang-undangan yang mengikat yaitu Peraturan Menteri Hukum dan Hak Asasi Manusia Nomor 10 Tahun 2020 Tentang Syarat Pemberian Asimilasi dan Hak Integrasi bagi Narapidana dan Anak dalam Rangka Pencegahan dan Penanggulangan Penyebaran Covid-19.Kata Kunci: Narapidana, Asimilasi, Integrasi, Covid-19 Abstract Regulation of the Minister of Law and Human Rights Number 10 of 2020 is a government policy in preventing and controlling the spread of Covid-19 that occurs in Correctional Institutions and State Detention Centers. This research was conducted to determine the implementation of the Minister of Law and Human Rights Regulation Number 10 of 2020 and to analyze the effect of the Ministerial Regulation on the Number of Inmates in East Java Detention Centers. The research method used in this study is a normative law research method which refers to binding laws and regulations, namely the Minister of Law and Human Rights Regulation Number 10 of 2020 concerning Conditions for Providing Assimilation and Integration Rights for Prisoners and Children in the Context of Prevention and Control of Spread Covid-19.Keywords: Prisoners, Assimilation, Integration, Covid-19
Genotoxicity from metronidazole detected in vitro, but not in vivo, in healthy dogs in a randomized clinical trial
Authors: Peterson Hannah M. , Manley Colette I. , Trepanier Lauren A. , Pritchard Jessica C. 
Published: November 2022

Abstract

OBJECTIVE
To determine whether metronidazole (MTZ), at recommended therapeutic dosages in dogs, induces peripheral blood cell (PMBC) genotoxicity, using the γ-H2AX assay as a sensitive measure of DNA breaks. The secondary aim was to assess dose-dependent genotoxicity in vitro in dog and cat PBMCs exposed to increasing MTZ concentrations.

ANIMALS
12 healthy employee- and student-owned dogs and blood samples from 2 other healthy untreated dogs and 2 healthy untreated cats.

PROCEDURES
Screened dogs were randomized to receive lower-dose MTZ (7.5 mg/kg, PO, q 12 h) or higher-dose MTZ (20 mg/kg, PO, q 12 h) for 7 days. Blood was drawn at baseline, after the 1 week of treatment, and after a 1-week washout, for DNA damage assessment and serum MTZ concentration measurements. For in vitro studies, PBMCs from untreated healthy dogs and cats were exposed to 0 to 500 μg/mL MTZ.

RESULTS
No dogs showed a significant increase in DNA damage at these MTZ dosages for 1 week. The highest serum MTZ concentration observed 1 hour after dosing was 36 μg/mL. In vitro, MTZ led to a significant increase in DNA damage at 100 μg/mL in both canine and feline PBMCs.

CLINICAL RELEVANCE
Although MTZ was not significantly genotoxic in vivo in the healthy dogs in this study, MTZ was significantly genotoxic to canine PBMCs in vitro at 3-fold higher concentrations than those documented in vivo. The safety of MTZ in clinically ill dogs, which may have impaired MTZ clearance or DNA repair, should be assessed next.
عفة نبي الله يوسف  في التوراة والقران الكريم وأثرها في تربية الشباب
Authors: Al-Janabi Ali Dawood Khalaf 
Published: November 2022

يتناول هذا البحث الحديث عن عفة نبي الله يوسفالتي ذكرت في قصته والتي جاءت أحداثها في التوراة والقران الكريم، وأثر هذه العفة في تربية الشباب في هذا العصر، فقصة نبي الله يوسف u قد تضمنت أعمال العقل المرتكز على الإيمان أمام المغريات, ووظف طاعته لله عز وجل ليكبح جماح المعصية مع امرأه العزيز، والتوراة قد سبقت القران الكريم من حيث التسلسل الزمني في بيان عفته، وجاء القران الكريم ليظهر وبيقين قاطع عفة هذا النبيu ليكون قدوة لمن بعده من الشباب , في هذا الزمان ومع الانتشار الواسع للمواقع الالكترونية وتنوع تقنياتها التي وفرت الخلوة بين الجنسين , فقصته u نستلهم منها ركائزاً توجيهيه للشاب في عصرنا هذا , ونحن بحاجة ماسة الى العفة والالتزام الاخلاقي المصاحب لأن يكونوا قدوة وقادة لبعضهم البعض كي يصونوا أنفسهم ويصونوا غيرهم بعفتهم وبإخلاصهم لربهم وطاعته كما فعل نبي الله يوسف u حين أتيحت له كل وسائل المعصية مع أمراءه العزيز.
الأسئلة الخمسة وأجوبتها للشيخ العلامة احمد بن محمد مكي الحنفي الحموي دراسة وتحقيق
Authors: Hassoun Mahmoud Ali 
Published: November 2022

ان عنوان الكتاب هو الاسئلة الخمسة واجوبتها وقد حاول المؤلف من خلالها عرض المشاكل والاسئلة التي صعبت على السائل بصورة مبسطة والاجابة عنها بتفصيل دقيق وتحقيق سديد بما يتناسب مع سؤال السائل بحيث لايبقى للسائل او من يطلع عليها ادنى شك في دقة الاجابة وصحتها ويدل هذا على ذكاء المصنف وتبحره ف علم الاصول والفقه مع ما يمتلكه من اطلاع واسع لعلوم متعددة واسعة وعلى الخصوص اللغوية والشرعية منها
أثـر استـخدام نموذج التفكير التحفيزي (ARSC) في تنمية التفكير المستقبلي لدى طالبات الصف الخامس العلمي في مادة الرياضيات
Authors: Omar Tahani Ghaleb 
Published: November 2022

هدف البحث الحالي للتعرف على" أثر استخـدام نموذج التفكير التحفيزي (ARSC) في تنمية التفكير المستقبلي لدى طالبات الصف الخامس العلمي في مادة الرياضيات", ولأجل التحقق من صحة الفرضية أجرت الباحثة تجربة استغرقت فصلاً دراسيا كاملاً للسنة الدراسية (2020-2021) ,إذ اعتمدت الباحثة التصميم التجريبي لمجموعتين إحداهما تجريبية والأخرى ضَابطة ذات الضبط الجزئي والاختبار البعدي اختبار التفكير المستقبلي .
اقتصر البحث في حدوده على طالبات الصف الخامس العلمي في مدرسة سيد المرسلين التابعة إلى المديرية العامة لتربية صلاح الدين/تكريت ، للعام الدراسي (2020-2021 م) . إذ بلغت عينة البحث (52) طالبة ,وكانت شعبة (ب) تمثل طالبات المجموعة التجريبية المتكونة من (26) طالبة, وشعبة (أ) تمثل طالبات المجموعة الضابطة المتكونة من(26) طالبة , كَوفئت مجموعتا البحث في عدد من المتغيرات وهي(العمر الزمني , المعلومات السابقة لمادة الرياضيات, تحصيل العام الماضي, اختبار التفكير المستقبلي القبلي ),وتم إعداد أداة البحث وهو اختبار التفكير المستقبلي ,الذي تألف من (25) فقرة ,وتم التأكد من صدق الأداتين بعد عرضها على المحكمين , وتم تحليل البيانات ومعالجتها إحصائيا باعتماد البرنامج الاحصائي (SPSS).
DEVELOPMENT OF MATHEMATICAL LEARNING DEVICES BASED ON THE POE (PREDICTION, OBSERVATION, EXPLANATION) MODEL IN THE MATERIAL OF CONSTRUCTING FLAT SIDE SPACES
Authors: Faisal Bakti  , Rezi Ariawan  
Published: November 2022

Mathematical creative thinking is the ability to produce varied answers or ideas to solve problems in mathematics. This study aims to build a valid learning device on flat-sided geometry using the POE model (Prediction, Observation, Explanation). The learning tools developed were syllabus, lesson plans, and LKPD on the flat side space building material. This type of research is development research with the ADDIE model, modified into three stages (Analysis, Design dan Development) without the implementation and evaluation stages. The research data collection instrument was a learning device validation sheet in a syllabus, lesson plans, and LKPD. Analysis of the data used is descriptive data analysis that describes the level of validity of the product. This study yielded a valid syllabus, lesson plans, and LKPD with 83.65%, 87.86%, and 86.31%, respectively. This study concludes that the Development of mathematical learning tools based on the POE model on the flat-sided geometry material has been tested for validity
Social and Psychological Aspects of Managing Human Resources at Industrial Enterprises in Transition to Liberal-Market Model
Authors: Алиев Ульви Алиевич , Сигов Виктор Ивглафович 
Published: November 2022

Актуальность исследования обосновывается тем, что переход от патерналистской к рыночной модели управления человеческими ресурсами предприятий принципиальным образом меняет систему социально-трудовых отношений. В статье показано, что модель государственного патернализма, которая лежала в основе государственного подхода к управлению человеческими ресурсами предприятий, подвергается серьезным изменениям при переходе к управлению на основе либерально-экономической модели. Обосновано, что успешность деятельности предприятий на этапе перехода к парадигме либерально-рыночных отношений будет определяться способностью менеджмента модифицировать управление человеческими ресурсами.
The transition from paternalistic to market model of human resources management at enterprises dramatically changes the system of social-labor relations, which determines the relevance of the research. We demonstrate that the model of state paternalism that formed the basis of government approach to human resources management at enterprises is being changed in transition to management based on liberal-economic model. We prove that successful performance of enterprises during the transition to the paradigm of liberal-market relations will rely on the ability of management to modify the human resources management.
New Forms of Employment and Information Security
Authors: Воротынская Александра Михайловна 
Published: November 2022

В статье анализируются современные тенденции российского рынка труда, связанные с изменением структуры социально-трудовых отношений, в частности взаимодействия между работодателем и наемными работниками. В современном обществе расширяются масштабы использования нестандартных форм занятости в связи с процессами цифровизации экономики. Анализируются положительные и отрицательные стороны фриланса как для работодателя, так и для самих нештатных сотрудников. Проводится анализ влияния гибких форм занятости в сфере IT-технологий на процессы обеспечения информационной и экономической безопасности предприятия. По мнению автора, целесообразность использования виртуальных рабочих мест для специалистов, связанных с информационными системами и технологиями, должна быть определена работодателем на основе ряда исследуемых в статье факторов. В статье обосновывается взаимосвязь труда фрилансеров в России с теневой экономикой через распространение и влияние неформальной занятости на деформализацию экономики посредством ее частичного перехода в теневую сферу. Выходом из этого должна стать легализация неформального сектора.
The article analyses modern trends in the Russian labour market resulted from changes in the structure of social and labour relations particularly within relations between an employer and employees. In modern society there is a growing drive for implementation of non-standard forms of employment due to ongoing economy digitalization processes. The paper provides analyses of positive and negative sides of freelance with regard to both employer and freelancers themselves. The study analyses the impact of flexible forms of employment in IT technologies on the processes ensuring information and economic security of the businesses. According to the author advisability of the use of virtual workplaces for specialists engaged in IT systems and technologies should be defined by an employer on the basis of a number of factors under the study hereof. The article justifies the linkage between freelancers activity in Russia with the shadow economy through the spread and influence of informal employment on economy informalization by its partial transfer to the shadow sector. The author concludes with a proposal to ensure the way out of this situation through legalization of informal sector.
Comparative Analysis of Finance Indicators of Leading Petrochemical Companies of Russia, Saudi Arabia and USA
Authors: Хайрутдинов Ильдус Ринатович 
Published: November 2022

В условиях трансформации мировой нефтехимической отрасли, ее состояние в каждой стране можно оценить, проанализировав финансовое состояние компаний-лидеров. Сравнение по основным финансовым показателям показывает в каком направлении движутся компании, как они отреагировали на падение цен на энергоресурсы и позволяет проанализировать их перспективы развития. В статье, на основе официальных данных из финансовых отчетов компаний, представлен сравнительный анализ компаний-лидеров по абсолютным и относительным показателям, с оценкой причин роста и падения основных финансовых результатов.
While global petrochemical industry is being transformed, its state in every country can be assessed by analyzing the condition of leading companies. Comparing the main finance indicators we can see the direction the companies are heading and their reaction to the fall in prices of energy resources, it also enables us to analyze the prospects of their development. On the basis of the data provided in financial reports, we make comparative analysis of leading companies in accordance with absolute and relative indices, studying the reasons for growth and fall of the main finance results.