bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determinan migrasi risen masuk ke Provinsi Jawa Barat periode 2000-2015
Authors: Noviandita Ardhianti , Prastowo Prastowo 
Published: August 2022

Abstract
Purpose – This study aims to analyze the factors influencing recent migration to West Java Province.
Methods – This study combines time series and cross-section data with panel data regression analysis methods.
Findings – The results of this study indicate that the ratio of wages and the ratio of the number of industries have a negative effect on recent migration to West Java Province. Meanwhile, the GRDP ratio and the ratio of the number of universities have no impact on recent migration to West Java Province.
Implication – The policy implications of this research are that the government needs to implement an equitable development strategy in all regions and make efforts to increase income and job opportunities in all areas.
Originality – This study contributes to analyzing the determinants of recent migration to West Java Province using panel data analysis

Abstrak
Tujuan – Penelitian ini bertujuan untuk menganalisis faktor-faktor yang mempengaruhi migrasi risen yang masuk ke Provinsi Jawa Barat.
Metode – Penelitian ini menggunakan gabungan data time series dan cross section dengan metode analisis regresi data panel.
Temuan – Hasil penelitian ini menunjukan bahwa rasio upah dan rasio jumlah industri berpengaruh negatif terhadap migrasi risen yang masuk ke Provinsi Jawa Barat. Sementara itu variabel rasio PDRB dan rasio jumlah perguruan tinggi tidak berpengaruh terhadap migrasi risen masuk ke Provinsi Jawa Barat.
Implikasi – Implikasi kebijakan dari penelitian ini yaitu pemerintah perlu melaksanakan strategi pembangunan yang merata di seluruh daerah, serta melakukan upaya meningkatkan pendapatan dan kesempatan kerja di seluruh daerah.
Orisinalitas – Penelitian ini berkontribusi dalam menganalisis determinan migrasi risen yang masuk ke Provinsi Jawa Barat dengan menggunakan analisis data panel.
PRODUCTION ORGANIZATION OF GRAPHICS PRODUCT
Authors: Vorontsova Darya , Fedchenko Hanna , Valchuk Olga 
Published: August 2022

Computer graphics is developing dynamically in various spheres of human life. Paying attention to the high dynamism of the world around us, the issue of optimizing the process of video, animation, character, advertising, avatar, etc. creation is becoming increasingly important. The graphic product requires the fastest production process without paying attention to the fact that it is a development of a feature film, a commercial project of various scales or a project of 10 frames. The analysis of the main achievements of specialists in the field of computer graphics revealed different approaches to the organization of graphic projects. In specialist’s works, attention is paid to the principles of graphic conveyors of major studios and film companies. The purpose of this work is to present recommendations for the organization of the process of developing a short video series by one person, taking into account the automation of the relevant stages of work, on the example of a video of social advertising. To implement this task, the scheme of the project workflow was proposed, where the main stages of creating graphic content are marked, the relevant software and selected parts of the workflow such as preproduction, production and postproduction. The following software tools were selected for the project implementation: Z-Brush, Blender, Autodesk Maya, Adobe After Effects. The analysis of the development algorithm showed the critical points of the scheme, which reduce the speed of the project. To avoid this, it was proposed the technique of "pipeline". As a result of research the methodologies of the graphics pipeline organization was raised, and the beneficial effects of reliable workflow management were illustrated. A visual and detailed form of presentation of the creating a graphic product stages using the "pipeline" technique will help increase the level of knowledge among beginners.
A Methodical Approach of Trialling New Technology Towards Advancement in Drilling Performance
Authors: Wusten Andre , Mounzer Fadi 
Published: August 2022

Abstract
Many organizations have a shared goal of always exploring new and different ways to improve operational efficiencies while lowering associated operational expenditures. During economic downturns or periods of suppressed pricing such as the oil and gas industry has experienced in recent years, such programs attract more focus and attention.
Adopting and refining the learning curve process is a crucial part of identifying potential areas of improvement and attaining high-quality performance increases while minimizing lost time.
It is also not uncommon for similar organizations to explore alternate tactics and new technology during difficult times. Those must be capable of overcoming identified bottlenecks and securing additional gains toward higher efficiency. In such instances, the ability to assess and quantify the advantages of the chosen efforts is critical. This is usually accomplished by establishing a stable baseline that may serve as a dependable benchmark.
In preparation for an upcoming drilling campaign, where equivalent circulating density (ECD) margins are critical, a North Sea operator used a similar structured approach to integrate a new innovative stabilizer design (ISD) into its standard bottom hole assembly (BHA) configuration as a replacement for the traditional spiral stabilizer with its known flaws.
The ISD's hydrodynamic design allows for enhanced displacement of fluid and cuttings along the tool, supporting improved ECD control. The objective was to compare and quantify the possible advantages of the new technology over conventional tools.
In each of the intended runs, an additional carrier sub, with vibration and pressure sensors, was placed directly below the stabilization points to ensure a reliable benchmark and qualitative comparison.
Following the trial runs, a full analysis was done in a collaborative effort involving all stakeholders concerned. The outcomes of the trial and study proved encouraging. As a result, the plan is to use the new stabilizer design in future drilling campaigns and explore additional documented benefits.
The concepts and techniques underlying the established learning curve are outlined in this paper, as well as how this ongoing work has contributed to improved performance and overall well design and delivery. The expected ECD challenges and limitations of the upcoming drilling campaign are highlighted. The report also explains the science underlying the tried-and-true new stabilizer design, as well as the novel features and sought-after benefits. In addition, the authors will discuss the conditions designed to provide an as close and qualitative comparison as possible, as well as the agreed-upon key performance indicators (KPIs) for this study. The data will be analysed, and the overall performance will be compared to offset wells. The report concludes with a brief discussion of the attained results and conclusions, as well as the plan forward with the tested technology.
Evaluating the Damage Content of Karbandi Using Frequency Domain Analysis (Case Study: Timche Haj-Mohammad-Qoli of Tabriz Historic Bazaar)
Authors: Ahani Elshan , Ahani Ali 
Published: August 2022

Abstract
In this study, an alternate method to evaluate structural systems, especially those with historical importance has introduced by applying Fourier Transform (FT) to the damage ratio of time history outcome in the frequency domain. The concept of damage content (DC) regarding the mechanical characteristics of the used material, including plastic strain, failure plane, and ultimate load-bearing capacity, along with drift value, record selection criteria, and architectural aspects, have employed. Due to its valuable aesthetic and architectural view, Timche Haj-Mohammad-Qoli of Tabriz Historic Bazaar, one of the traditional covered spaces with the complicated configuration of spatial masonry intersecting arches, selected for further assessment in the current research program. The required experimental samples for obtaining the mechanical properties and relevant geometrical measurements to prepare the numerical model of the structure obtained. The strong ground motions according to seismological and geological characteristics of the construction site selected. The records with different durations were merged by Fourier Transform (FT) and Damage Content (DC) analysis. According to the outcomes, the damage state of the structure due to the imposed strong motion at every stage of the lateral loading from the failure initiation to the final collapse was traceable. As a straightforward outcome, the vulnerability of the near-field earthquakes is more tangible than that of the far-field earthquakes. The provided methodology could have proper use in future similar studies for evaluating the performance of the structures.
TRAIL-R deficient mice are protected from neurotoxic effects of amyloid-β
Authors: Benedetto Giulia Di , Burgaletto Chiara , Serapide Maria Francesca , Caltabiano Rosario , Munafò Antonio , Bellanca Carlo Maria , Mauro Rosaria Di , Bernardini Renato , Cantarella Giuseppina 
Published: August 2022

Abstract
TRAIL, a member of TNF superfamily, is a potent inducer of neuronal death. Neurotoxic effects of TRAIL appear mediated by its death receptor TRAIL-R2/DR5. To assess the role of TRAIL/TRAIL-R2 pathway in AD-related neurodegeneration, we studied the impact of the treatment with amyloid-β (Aβ) upon cell viability and inflammation in TRAIL-R-deficient mice (TRAIL-R-/-). Here, we demonstrate that the lack of TRAIL-R2 protects from death cultured TRAIL-R-/- mouse embryonic hippocampal cells undergone treatment with either Aβ1–42 or TRAIL. Consistently, stereotaxic injection of Aβ1–42 resulted in blunted caspase activation, as well as in reduction of JNK phosphorylation and increased AKT phosphorylation in TRAIL-R-/- mice. Moreover, the lack of TRAIL-R2 was associated with blunted constitutive p53 expression in mice undergone Aβ1–42 treatment, as well as in decrease of phosphorylated forms of tau and GSK3β proteins. Likewise, TRAIL-R2 appears essential to both TRAIL and Aβ-mediated neurotoxicity and inflammation. Indeed, hippocampi of TRAIL-R-/- mice challenged with Aβ1–42, showed a scanty expression of microglial (Iba-1) and astrocytic (GFAP) markers along with attenuated levels of IL-1β, TNF-α, NOS2 and COX2. In conclusion, the bulk of these results demonstrate that the constitutive lack of TRAIL-R2 is associated with a substantial reduction of noxious effects of Aβ1–42, providing further evidence on the prominent role played by TRAIL in course of Aβ-related neurodegeneration and confirming that the TRAIL system represents a potential target for innovative AD therapy.
Sporadic amyotrophic lateral sclerosis: integral model of pathogenesis and therapy options
Authors: Doroshenko Oleksii 
Published: August 2022

Abstract
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive central nervous system degenerative disease, in most cases within 2–3 years inevitably leading to mixed tetraplegia and subsequent death from diaphragmatic paralysis. While for almost half of hereditary cases, mutations are identified as the cause of the disease, the sporadic form of ALS (sALS), due to the polymorphism and complexity of the putative developmental mechanisms raises a lot of questions. To date, there are no sufficiently effective pathogenetic methods for the disease treatment. All the above mentioned makes ALS one of the most relevant and, at the same time, unexplored topics in neurology. In this review, the author combines the most important, in his opinion, currently known factors of sALS pathogenesis, including enterovirus infection, TAR DNA binding protein 43 (TDP-43) pathology, human endogenous retrovirus-K (HERV-K) reactivation, RNA-specific editase 1 (ADAR2) dysfunction and oxidative stress (OS) into a unified illustrative model. The author is suggesting a probable sequence of pathogenetic links, based on data regarding the presence of pathophysiological links between them and their ability to cause the typical for sALS histochemical pattern. Simultaneously, the author makes assumptions about the developmental mechanisms for some secondary disorders typical for sALS. In conclusion, in accordance with the derived model, the author conducts a review of possible pharmacological interventions of pathogenetic and etiotropic therapy. The author describes both clinically proven effective drugs, and previously unstudied, but extremely promising compounds that require further testing.
Prediction and diagnostics of crises and critical states in an unusual vibro-impact system with soft impact
Authors: Lizunov Petro , Pogorelova Olga , Postnikova Tetiana 
Published: August 2022

Abstract
This article studies the dynamical behavior of a two-body 2-DOF vibro-impact system when changing both its parameters and external load parameters. The considered vibro-impact system is a model of a platform vibrator with shock used in the construction industry for compaction and molding of concrete products. We call it unusual because of its specific features, namely, the huge mass of the upper body, which breaks away from the lower body, "bounces" a very short distance, and for a very short time is in free flight; then it falls on the rubber gasket, the soft impact occurs, after which it "bounces" again and so on. The soft impact is simulated by nonlinear contact interactive force in accordance with Hertz's quasi-static contact law. Some changes in the system parameters can increase the efficiency of concrete compaction, but with the same changes, undesirable and even dangerous phenomena occur in our strongly nonlinear non-smooth discontinuous vibro-impact system. The system exhibits interior and boundary crises, chaotic motion, crisis-induced intermittency, transient chaos that generates a chaotic regime, and a hysteresis zone with coexisting regimes obtained for different initial conditions. Diagnostics of the observed modes is carried out by several methods, both conventional and less common. These are time histories, phase portraits with Poincaré maps, Fourier spectra, Lyapunov exponents, wavelet characteristics obtained using Continuous Wavelet Transform, and fractal structures. Numerous figures and tables that clearly and convincingly demonstrate the results of numerical studies accompany the presentation.Mathematics Subject Classification (2000) 37G35 · 37N15 · 37L30 · 65T60
A COVID-19 model incorporating variants, vaccination, waning immunity, and population behavior
Authors: LaJoie Zachary , Usherwood Thomas , Sampath Shailen , Srivast Vikas 
Published: August 2022

Abstract
Vaccines for COVID-19 have allowed countries to combat the spread of the disease. However, new variants have resulted in significant spikes in cases and raised severe health and economic concerns. We present a COVID-19 model to predict coupled effects of vaccine multiple-dose roll-out strategies, vaccine efficacy, waning immunity, population level of caution, level of safety, under-reporting of cases, and highly prevalent variants such as the Delta (B.1.617.2) and Omicron (B.1.1.529). The modeling framework can incorporate new variants as they emerge to give critical insights into the new cases and guide public policy decision-making concerning vaccine roll-outs and reopening strategies. The model is shown to recreate the history of the COVID-19 for five countries (Germany, India, Japan, South Africa, and the United States). Parameters for crucial aspects of the pandemic such as population behavior, new variants, vaccination, and waning immunity can be adjusted to predict pandemic scenarios. The model was used to conduct trend analysis to simulate pandemic dynamics taking into account the societal level of caution, societal sense of safety, and the proportions of individuals vaccinated with first, second, and booster doses. We used the results of serological testing studies to estimate the actual number of cases across countries. The model allows quantification of otherwise hard to quantify aspects such as the infectious power of variants and the effectiveness of government mandates and population behavior. Some example cases are presented by investigating the competitive nature of COVID variants and the effect of different vaccine distribution strategies between immunity groups.
Novel selectively amplified DNA sequences in the germline genome of the Japanese hagfish, Eptatretus burgeri
Authors: Nagao Kohei , Otsuzumi Tomoko , Chinone Hitomi , Sasaki Takashi , Yoshimoto Junko , Matsuda Makiko , Kubota Souichirou , Goto Yuji 
Published: August 2022

Abstract
In the Japanese hagfish Eptatretus burgeri, 16 chromosomes (eliminated [E]-chromosomes) have been lost in somatic cells (2n = 36), which is equivalent to approx. 21% of the genomic DNA in germ cells (2n = 52). At least seven of the 12 eliminated repetitive DNA families isolated in eight hagfish species were selectively amplified in the germline genome of this species. One of them, EEEb1 (eliminated element of E. burgeri 1) is exclusively localized on all E-chromosomes. Herein, we identified four novel eliminated repetitive DNA families (named EEEb3–6) from this species through PCR amplification and suppressive subtractive hybridization (SSH) combined with Southern-blot hybridization. EEEb3 was mosaic for 5S rDNA and SINE element. EEEb4 was GC-rich repeats and had one pair of direct and inverted repeats, whereas EEEb5 and EEEb6 were AT-rich repeats and composed of several sub-repeats. Interestingly, all but EEEb3 were transcribed in the testes, although no functional open reading frame (ORF) was found. We conducted fluorescence in situ hybridization (FISH) to examine the chromosomal localizations of EEEb3–6 and EEEb2, which was initially isolated from the germline DNA of this species. All of them were completely colocalized on all EEEb1-positive E-chromosomes. The estimation of the copy number by slot-blot hybridization revealed that (i) EEEb1–6 family members occupied 39.9% of the total eliminated DNA, and (ii) a small number of repeats were retained in somatic cells, suggesting the incomplete elimination. These results provide new insights about the mechanisms involved in the chromosome elimination and the evolution of E-chromosomes.
Environmental Data Mining to Determine Coral Bleaching Severities
Authors: Halide Lidemar , Andika - , Marhaeni M. , Sulva Magfira , Akhir N. Y. , Syafrizal M. , Halide Halmar 
Published: August 2022

Abstract
Coral bleaching events could be viewed as a resultant of complex interactions involving various environmental factors. Just recently, a TEL (seawater Temperature-ENSO-Longitude) model is developed to predict the global bleaching events during the single 2016 El Niño episode. The model has a modest skill of approximately 50% predictability. In an attempt to improve coral bleaching prediction skill, here, two models are developed: an extended TEL model and a statistical model that combines multivariate and supervised classification techniques. The skills of both models are assessed in predicting bleaching events from three coral regions during several El Niño episodes. Two important findings are found. First, it is revealed that seawater salinity, ENSO, and Madden Julian Oscillation have stronger effect than seawater temperature in coral bleaching events. This has an important consequence to the fate of coral ecology when these phenomena are also subjected to change under global warming. Second, the predictability of our developed is 74% which is higher than that of the TEL model. Our model could serve as a tool for reef managers on communicating bleaching risk earlier. It could also be used for monitoring and reservation plans to mitigate the detrimental effect of various environmental stressors on corals.
Positive end expiratory pressure and respiratory system resistance between self-inflating bag and T- piece resuscitator in a cadaveric piglet lung model
Authors: Shah Dharmesh , Tracy Mark , Hinder Murray , Badawi Nadia 
Published: August 2022

Abstract
PurposeIn neonatal resuscitation, using a T-piece resuscitator (TPR) is used widely, however the evidence is limited for the use in infants born at term gestation. The aim of this study was to compare the positive end expiratory pressure (PEEP) and respiratory system resistance (Rrs) using TPR and self-inflating bag (SIB) in a cadaveric piglet model.Methods Cadaveric newborn piglets were tracheotomised, intubated (cuffed tube) and leak tested. Static lung compliance was measured. Positive pressure ventilation was applied by TPR and SIB in a randomized sequence varying, inflations per minute (40, 60 and 80/min) and peak inspiratory pressures (18 and 30 cmH2O). PEEP was constant at 5 cmH2O. The lungs were washed with saline and static lung compliance re-measured; ventilation sequences were repeated. Lung inflation data for the respiratory mechanics were measured using a respiratory function monitor and digitally recorded for both pre and post lung wash inflation sequences. A paired sample t-test was used to compare the mean and standard deviation.ResultsThe mean difference in PEEP (TPR vs SIB) was statistically significant at higher inflation rates of 60 and 80 bpm. At normal lung compliance, mean difference was 1.231 (p = 0.000) and 2.099 (p = 0.000) with PIP of 18 cmH2O and 30 cmH2O respectively. Significantly higher Rrs was observed when using a TPR with higher inflation rates of 60 and 80 bpm at varying lung compliance.ConclusionsTPR is associated with significantly higher PEEP in a compliant lung model, which is probably related to the resistance of the TPR circuit. The effect of inadvertent PEEP on lung mechanics and hemodynamics needs to be examined in humans. Further studies are needed to assess the delivered PEEP using various SIB with PEEP valves available commercially including the SIB with inbuilt PEEP valve.
Robot-assisted segmentectomy with improved inflation-deflation combined with the intravenous indocyanine green method
Authors: Hao Xu , Xiaoyan Chang , Linyou Zhang 
Published: August 2022

Abstract
Purpose
To investigate the perioperative outcomes of patients who underwent robot-assisted thoracoscopic (RATS) segmentectomy for identifying the intersegmental plane (ISP) by modified inflation-deflation (MID) combined with near-infrared fluorescence imaging with the intravenous indocyanine green (ICG) method and to assess the feasibility of this method in a large-scale cohort according to the type of segmentectomy performed.
Methods
We retrospectively analysed the perioperative data of a total of 155 consecutive patients who underwent RATS segmentectomy between April 2020 and December 2021. Data from the operation, including the demarcation status of the intersegmental plane, were analysed retrospectively.
Results
The mean operative time and estimated blood loss were 125.56 ± 36.32 minutes and 41.81 ± 49.18 mL, respectively. Good demarcation of the intersegmental plane was observed in 150 (96.77%) patients, with no correlation with the type of resected segments or the surgical method. Postoperative complications of Clavien–Dindo classification grade 3 or more were observed in 4 patients (2.58%), and no ICG-related adverse events were noted.
Conclusion
Demarcation of the intersegmental plane by MID combined with ICG is feasible regardless of the type of segmentectomy and can be commonly applied in robot-assisted segmentectomy.