bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validation of Non-invasive Measurement of Cardiac Output: Using Whole-Body Bio-impedance Versus Inert Gas Rebreathing in Healthy Women Undergoing In Vitro Fertilisation
Authors: Jaspal Raj-Kamael , Allen Mae , Cornette Jerome , Rizopoulos Dimitris , Lees Christoph 
Published: August 2022

Abstract
Background
Haemodynamic assessment in and before pregnancy is becoming increasingly important in relation to pregnancy complications and outcomes. Different methodologies exist but there is no gold-standard technique for non-invasive measurement of cardiac output (CO). We sought to assess two methods of CO measurement in healthy women undergoing in vitro fertilisation cycles (IVF). This was a prospective longitudinal study of 71 women aged 18–44 years planning IVF undergoing CO measurements obtained via inert gas rebreathing (IGR) using Innocor™ and whole-body bio-impedance (WBI) using Nicas™ to assess the reproducibility between the methods. Four visits occurred at which both techniques were used: initial assessment, embryo transfer, day of pregnancy test and 4 weeks post-transfer (regardless of whether conception occurred). Cross-sectional agreement of the methods was assessed using the calculation of bias, percentage error and limits of agreement (LOA) via the Bland–Altman analysis. Longitudinal agreement of the methods was assessed using a 4-quadrant plot with concordance rate, angular bias and radial limits of agreement (%).

Results
One hundred and thirteen measurements from 44 participants were suitable for cross-sectional (Bland–Altman) analysis. IGR (Innocor™) Mean CO was 4.61 L/min and 5.05 L/min with WBI (Nicas™). The bias was 0.44 L/min. The percentage error was 76% and intra-correlation coefficient was 0.135 (95% CI −0.43–0.306). Fifty-nine measurements from 28 participants were suitable for longitudinal (4Q-plot) analysis. The concordance rate was 64.4%, angular bias – 0.14, and radial limits of agreement + − 13.25°.

Conclusion
There was poor cross-sectional and longitudinal agreement between inert gas rebreathing and whole-body bio-impedance techniques. These techniques cannot be used interchangeably when measuring CO in women undergoing IVF, and these results may be more generalizable, to women in the peri-conception period.
Behavioral tectonics: agentBody prototypes and the compression of tectonics
Authors: Snooks Roland 
Published: August 2022

AbstractThis research demonstrates the development of a tectonic approach to architecture through an experimental, iterative methodology. It is a synthetic approach where tectonics and form are engaged in a non-hierarchical negotiation. An architecture where expression, ornament, structure and their spatial consequences are intertwined and inseparable.The design research posited here has been conducted over the past nine years through the sustained development of a series of architectural tectonic experiments called the agentBody Prototypes. These prototypes reify an ambition to compress surface, structure and ornament into a single irreducible assemblage. The agentBody Prototypes are a series of fourteen proto-architectural projects, or fragments, with lead design by Roland Snooks, and research, development and fabrication by the RMIT Architecture | Tectonic Formation Lab.The paper describes the wider context of this work and includes a brief chronological overview of this trajectory, followed by a series of observations drawn from critical reflection. This paper attempts to draw out the architectural design implications that have emerged through a specific interaction of algorithmic design, and robotic fabrication.
Artificial Intelligence, Autonomous Drones and Legal Uncertainties
Authors: Hartmann Jacques , Jueptner Eva , Matalonga Santiago , Riordan James , White Samuel 
Published: August 2022

AbstractDrones represent a rapidly developing industry. Devices initially designed for military purposes have evolved into a new area with a plethora of commercial applications. One of the biggest hindrances in the commercial developments of drones is legal uncertainty concerning the legal regimes applicable to the multitude of issues that arises with this new technology. This is especially prevalent in situations concerning autonomous drones (ie drones operating without a pilot). This article provides an overview of some of these uncertainties. A scenario based on the fictitious but plausible event of an autonomous drone falling from the sky and injuring people on the ground is analysed from the perspectives of both German and English private law. This working scenario is used to illustrate the problem of legal uncertainty facing developers, and the article provides valuable knowledge by mapping real uncertainties that impede the development of autonomous drone technology alongside providing multidisciplinary insights from law as well as software electronic and computer engineering.
How Can “Overall Progress and Development” Fail in Post-Conflict Societies? Securitization of the 2005–07 Stabilization and Association Agreement Negotiations in Republika Srpska
Authors: Kočan Faris 
Published: August 2022

AbstractIn this article, we analyze how the Stabilization and Association Agreement (SAA), which signalizes the overall (positive) progress and development of the potential candidate country of the post-Yugoslav space, is not straightforwardly translated as a benchmark for progress and development by the political elite. Drawing on securitization theory in order to understand the grammar of security, the wider discursive context, and the position of power and authority in RS during the analyzed period – and informed by the triangulation of content and discourse analysis – we show how the negotiations for the SAA were (mis)used in order to present both the “internal and external Other” as an existential threat for Republika Srpska. Our analysis shows that although the securitizing acts of the political elite from RS did not succeed in terms of the final outcome as the SAA was signed, certain security narratives, which are present in the contemporary sociopolitical landscape in BiH, have been constructed during this period and embedded into the wider discursive context and consolidated the position of power and authority of Milorad Dodik’s SNSD.
Short-term effects of goat milk yogurt-containing angiotensin-converting enzyme inhibitory peptides and two raisin varieties on subjective appetite, blood pressure and glycaemic responses in healthy adults. Results from a randomised clinical trial
Authors: Papakonstantinou Emilia , Manolopoulou Eugenia , Papamichalopoulos Argyris , Kounenidaki Chryssi , Mitrogeorgou Theodora , Georgalaki Marina , Tsakalidou Effie 
Published: August 2022

AbstractGoat milk yogurt (GMY) and raisins are popular foods with a favourable nutrient profile. Our aim was to determine the glycaemic index (GI) and postprandial responses to GMY-containing angiotensin-converting enzyme inhibitory (ACE-I) peptides carrying the RPKHPINHQ isracidin fragment and two Greek raisin varieties in an acute feeding setting. A total of twelve healthy participants (four male and eight female) consumed breakfast study foods containing 25 g available carbohydrate on seven occasions over a 3- to 9-week period: food 1: D-glucose (25 g) served as the control and was consumed on three separate occasions; food 2: GMY (617·28 g); food 3: Corinthian raisins (37·76 g); food 4: Sultana raisins (37·48 g) and food 5: GMY & C (308·64 g GMY and 18·88 g C). Postprandial glucose was measured over a 2 h period for the determination of GI and glycaemic load (GL). Subjective appetite ratings (hunger, fullness and desire to eat) were assessed by visual analogue scales (100 mm) at 0–120 min. Blood pressure (systolic and diastolic; BP) was measured at baseline and 120 min. GMY provided low GI (26), C and S provided high GI/low GL (75/10 and 70/9, respectively) and GMYC provided low GI (47) values on glucose scale compared with D-glucose. Peak blood glucose rise was significantly lower only for GMY and GMYC compared with reference food (D-Glucose), as well as C and S (Pfor all < 0·05). No differences were observed between test foods for fasting glucose, BP and subjective appetite. In conclusion, GMY and GMYC attenuated postprandial glycaemic responses, which may offer advantages to glycaemic control.
An extension of the van Hemmen–Ando norm inequality
Authors: Najafi Hamed 
Published: August 2022

AbstractLet
$C_{\||.\||}$
be an ideal of compact operators with symmetric norm
$\||.\||$
. In this paper, we extend the van Hemmen–Ando norm inequality for arbitrary bounded operators as follows: if f is an operator monotone function on
$[0,\infty)$
and S and T are bounded operators in
$\mathbb{B}(\mathscr{H}\;\,)$
such that
${\rm{sp}}(S),{\rm{sp}}(T) \subseteq \Gamma_a=\{z\in \mathbb{C} \ | \ {\rm{re}}(z)\geq a\}$
, then
\begin{equation*}\||f(S)X-Xf(T)\|| \leq\;f'(a) \ \||SX-XT\||,\end{equation*}
for each
$X\in C_{\||.\||}$
. In particular, if
${\rm{sp}}(S), {\rm{sp}}(T) \subseteq \Gamma_a$
, then
\begin{equation*}\||S^r X-XT^r\|| \leq r a^{r-1} \ \||SX-XT\||,\end{equation*}
for each
$X\in C_{\||.\||}$
and for each
$0\leq r\leq 1$
.
Surgical approaches for pleomorphic adenoma of the parapharyngeal space
Authors: Al Zadjali F , Chabrillac E , Vergez S 
Published: August 2022

AbstractObjectiveThis study aimed to analyse the outcomes of surgery for pleomorphic adenoma of the parapharyngeal space in relation to the surgical approach.MethodThis was a single-centre retrospective data analysis conducted from January 2008 to December 2020 on all patients who underwent operation for pleomorphic adenoma originating from the parapharyngeal space.ResultsTwenty-one patients with a mean age of 52.6 years were included. The transparotid-transcervical approach was the most common (52.4 per cent,n =11) surgical approach, followed by transoral robotic surgery (28.6 per cent,n =6) and conventional transoral surgery (19 per cent,n =4). Post-operative complications included nine cases of transient partial facial nerve palsy and two cases of Frey's syndrome after the transparotid-transcervical approach and 2 cases of transient trismus and 1 pharyngeal wound dehiscence in the conventional transoral approach group. Complete macroscopic excision was always achieved, and no recurrence occurred during follow up.ConclusionThese three approaches can provide adequate tumour visualisation, a high rate of clear excisional margins and an acceptable morbidity.
A systematic review and meta-analysis of the role of doxycycline in chronic rhinosinusitis
Authors: Chan D , Ooi E , Khalid O 
Published: August 2022

AbstractObjectiveThe objective of this systematic review and meta-analysis was to evaluate the role of doxycycline in the management of chronic rhinosinusitis.MethodThis was a systematic review using Ovid Medline, Cinahl, Scopus and Cochrane and was limited to meta-analyses, systematic reviews and randomised, clinical trials. A combination of the following search terms was used: ‘sinusitis’, ‘nasal polyps’, ‘doxycycline’ and ‘tetracycline’. Raw means and standard deviations were extracted from the included studies. The meta-analysis was performed using mean differences of pre- versus post-doxycycline treatment.ResultsA total of 279 studies were screened, of which 5 studies met the criteria (all randomised, controlled trials published between 2010 and 2021). The interventions, endpoints and measured outcomes varied across all studies. Meta-analysis performed on pre- versus post-doxycycline treatment for Sino-Nasal Outcome Test-22, nasal polyp scores and symptom scores did not yield statistically significant results.ConclusionThis review identified a small number of high-quality studies on the use of doxycycline in chronic rhinosinusitis. There does not seem to be convincing evidence for the routine use of doxycycline in patients with chronic rhinosinusitis. Further research may try to identify certain phenotypes of chronic rhinosinusitis that may better respond to doxycycline.
The relationship between cognitive clusters and telomere length in bipolar-schizophrenia spectrum disorders
Authors: Gurvich Caroline , Thomas Natalie , Hudaib Abdul-Rahman , Van Rheenen Tamsyn E. , Thomas Elizabeth H. X. , Tan Eric J. , Neill Erica , Carruthers Sean P. , Sumner Philip J. , Romano-Silva Marco , Bozaoglu Kiymet , Kulkarni Jayashri , Rossell Susan L. 
Published: August 2022

AbstractBackgroundSchizophrenia and bipolar disorder are complex mental illnesses that are associated with cognitive deficits. There is considerable cognitive heterogeneity that exists within both disorders. Studies that cluster schizophrenia and bipolar patients into subgroups based on their cognitive profile increasingly demonstrate that, relative to healthy controls, there is a severely compromised subgroup and a relatively intact subgroup. There is emerging evidence that telomere shortening, a marker of cellular senescence, may be associated with cognitive impairments. The aim of this study was to explore the relationship between cognitive subgroups in bipolar-schizophrenia spectrum disorders and telomere length against a healthy control sample.MethodsParticipants included a transdiagnostic group diagnosed with bipolar, schizophrenia or schizoaffective disorder (n = 73) and healthy controls (n = 113). Cognitive clusters within the transdiagnostic patient group, were determined using K-means cluster analysis based on current cognitive functioning (MATRICS Consensus Cognitive Battery scores). Telomere length was determined using quantitative PCRs genomic DNA extracted from whole blood. Emergent clusters were then compared to the healthy control group on telomere length.ResultsTwo clusters emerged within the patient group that were deemed to reflect a relatively intact cognitive group and a cognitively impaired subgroup. Telomere length was significantly shorter in the severely impaired cognitive subgroup compared to the healthy control group.ConclusionsThis study replicates previous findings of transdiagnostic cognitive subgroups and associates shorter telomere length with the severely impaired cognitive subgroup. These findings support emerging literature associating cognitive impairments in psychiatric disorders to accelerated cellular aging as indexed by telomere length.
Integration of Product Markets when Labour Markets are Unionized
Authors: Sørensen Jan Rose 
Published: August 2022

Summary
This paper is a first attempt to analyse the consequences of
establishing the internal market when taking account of labour market
effects of product market integration. Our main focus is on market power,
and we show that both labour unions and firms may lose market power when
product markets become integrated. If this happens, it is likely that both
workers and capitalists become better off. On the other hand, if the firms
reestablish their market power through mergers or cooperation, capitalists
gain, whereas workers lose. If neither firms nor unions lose market power,
there are no effects of integration.
Efficient Knowledge Compilation Beyond Weighted Model Counting
Authors: KIESEL RAFAEL , TOTIS PIETRO , KIMMIG ANGELIKA 
Published: August 2022

AbstractQuantitative extensions of logic programming often require the solution of so called second level inference tasks, that is, problems that involve a third operation, such as maximization or normalization, on top of addition and multiplication, and thus go beyond the well-known weighted or algebraic model counting setting of probabilistic logic programming under the distribution semantics. We introduce Second Level Algebraic Model Counting (2AMC) as a generic framework for these kinds of problems. As 2AMC is to (algebraic) model counting what forall-exists-SAT is to propositional satisfiability, it is notoriously hard to solve. First level techniques based on Knowledge Compilation (KC) have been adapted for specific 2AMC instances by imposing variable order constraints on the resulting circuit. However, those constraints can severely increase the circuit size and thus decrease the efficiency of such approaches. We show that we can exploit the logical structure of a 2AMC problem to omit parts of these constraints, thus limiting the negative effect. Furthermore, we introduce and implement a strategy to generate a sufficient set of constraints statically, with a priori guarantees for the performance of KC. Our empirical evaluation on several benchmarks and tasks confirms that our theoretical results can translate into more efficient solving in practice.
Modeling the Lunar Radiation Environment: A Comparison Among FLUKA, Geant4, HETC‐HEDS, MCNP6, and PHITS
Authors: Zaman F. A. , Townsend L. W. , de Wet W. C. , Looper M. D. , Brittingham J. M. , Burahmah N. T. , Spence H. E. , Schwadron N. A. , Smith S. S. 
Published: August 2022

AbstractRadiation transport codes have been an increasingly important tool for studying the space radiation environment, which includes high‐energy and high‐nuclear‐charge particles. The unique advantage of transport models lies in covering a wider range of particles, energies, and angles than would be attainable in a laboratory or measurable by an instrument. However, since there are several transport codes developed by different teams that have contributed heavily to the literature, differences are expected between such codes. In this work, we use five such radiation transport codes (FLUctuating KAscade, GEometry ANd Tracking, High‐Energy Transport Code‐Human Exploration and Development in Space, Monte Carlo N‐Particle, and Particle and Heavy Ion Transport code System) to study the radiation environment near the Moon, specifically the lunar “albedo” radiation, which is the radiation emitted by the lunar surface through interactions with incident galactic cosmic rays and solar energetic particles. The primary goal of this paper is to provide a general characterization of the lunar albedo radiation and to find the areas where the modeled transport codes agree and disagree by using almost identical input parameters. The results of this work show overall good agreement between the codes. However, some areas of discrepancies exist that are reported herein. Thus, this paper equips the space weather and radiation biology communities with a comparison between popular radiation transport models applied to lunar albedo radiation. The overall agreement and, in some cases, discrepancies between these transport codes provide fundamental insight necessary for assessing code reliability and identifying where further study and improvements are needed to advance our understanding of lunar albedo radiation.
Impacts of Horizontal Resolution of the Lateral Boundary Conditions and Downscaling Method on the Performance of RegCM4.6 in Simulating the Surface Climate Over Central‐Eastern China
Authors: Xu Xiaoke , Huang Anning , Huang Qian , Zhang Yan , Wu Yang , Gu Chunlei , Cai Shuxin , Zhu Xueyan 
Published: August 2022

AbstractThis study investigated the impacts of horizontal resolution of lateral boundary condition (LBC) and downscaling method on the performance of RegCM4.6 in simulating the 2 m air temperature and precipitation over central eastern China. Two groups of experiments (direct downscaling experiments using LBC derived from the same reanalysis data but with different horizontal resolutions [0.75°, 1.5°, and 2.5°] and double‐nested downscaling experiment) with the model horizontal resolution of 20 km over central eastern China have been carried out. Results show that the direct downscaling experiments consistently outperform the double‐nested experiment to simulate the 2 m air temperature and precipitation over central eastern China, suggesting that adopting the direct downscaling method is appropriate to simulate the surface climate over central eastern China. Meanwhile, the direct downscaling experiments driven by the LBC derived from the reanalysis data with the horizontal resolution ranging from 0.75° to 2.5° display very comparable performance with a little better performance by adopting the LBC derived from the reanalysis data of much finer resolution. Further mechanism analysis indicates that much larger errors of LBC produced by the double‐nested downscaling method lead to the positive pressure biases and negative biases of water vapor convergence flux over Jianghuai Valley, which contribute to the much larger biases of precipitation and 2 m air temperature in the double‐nested downscaling experiment compared to the direct downscaling experiments. This study emphasizes that the direct downscaling method is superior to the double‐nested downscaling method for the simulations of 2 m air temperature and precipitation over central eastern China.
Paleointensity Estimates From the Pleistocene of Northern Israel: Implications for Hemispheric Asymmetry in the Time‐Averaged Field
Authors: Tauxe L. , Asefaw H. , Behar N. , Koppers A. A. P. , Shaar R. 
Published: August 2022

AbstractTwenty‐two sites, subjected to an IZZI‐modified Thellier‐Thellier experiment and strict selection criteria, recover a paleomagnetic axial dipole moment (PADM) of 62.2 ± 30.6 ZAm2 in Northern Israel over the Pleistocene (0.012–2.58 Ma). Pleistocene data from comparable studies from Antarctica, Iceland, and Hawaii, re‐analyzed using the same criteria and age range, show that the Northern Israeli data are on average slightly higher than those from Iceland (PADM = 53.8 ± 23 ZAm2, n = 51 sites) and even higher than the Antarctica average (PADM = 40.3 ± 17.3 ZAm2, n = 42 sites). Also, the data from the Hawaiian drill core, HSDP2, spanning the last half million years (PADM = 76.7 ± 21.3 ZAm2, n = 59 sites) are higher than those from Northern Israel. These results, when compared to Pleistocene results filtered from the PINT database (www.pintdb.org) suggest that data from the Northern hemisphere mid‐latitudes are on average higher than those from the southern hemisphere and than those from latitudes higher than 60°N. The weaker intensities found at high (northern and southern) latitudes therefore, cannot be attributed to inadequate spatiotemporal sampling of a time‐varying dipole moment or low quality data. The high fields in mid‐latitude northern hemisphere could result from long‐lived non‐axial dipole terms in the geomagnetic field with episodes of high field intensities occurring at different times in different longitudes. This hypothesis is supported by an asymmetry predicted from the Holocene, 100 kyr, and 5 million year time‐averaged geomagnetic field models.
Fine‐Scale Geothermal Heat Flow in Antarctica Can Increase Simulated Subglacial Melt Estimates
Authors: McCormack Felicity S. , Roberts Jason L. , Dow Christine F. , Stål Tobias , Halpin Jacqueline A. , Reading Anya M. , Siegert Martin J. 
Published: August 2022

AbstractAntarctic geothermal heat flow (GHF) affects the thermal regime of ice sheets and simulations of ice and subglacial meltwater discharge to the ocean, but remains poorly constrained. We use an ice sheet model to investigate the impact of GHF anomalies on subglacial meltwater production in the Aurora Subglacial Basin, East Antarctica. We find that spatially‐variable GHF fields produce more meltwater than a constant GHF with the same background mean, and meltwater production increases as the resolution of GHF anomalies increases. Our results suggest that model simulations of this region systematically underestimate meltwater production using current GHF models. We determine the minimum basal heating required to bring the basal ice temperature to the pressure melting point, which should be taken together with the scale‐length of likely local variability in targeting in‐situ GHF field campaigns.