bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Doubly Interpenetrated Cu(II)‐based Metal‐Organic Framework as a Heterogeneous Catalyst for the ipso‐Hydroxylation of Arylboronic Acids
Authors: Rani Pooja , Heena  , Pundir Niharika , Gauri  , Husain Ahmad , Bhasin K. K. , Kumar Girijesh 
Published: November 2022

AbstractA doubly interpenetrated Cu(II)‐organic framework with formula [{Cu2(L)2(4,4′‐bpdc)2(H2O)2} ⋅ 8H2O ⋅ CH3OH]α (1) (where, L=N2, N6‐di(pyridin‐4‐yl)naphthalene‐2,6‐dicarboxamide and 4,4′‐bpdc=[1,1′‐biphenyl]‐4,4′‐dicarboxylate ion) has been synthesized and characterized with the help of several spectroscopic and analytical techniques including single crystal X‐ray analysis. A single crystal X‐ray analysis reveals that 1 exhibit interpenetrated two‐dimensional sheet‐like structure containing elongated channels of cross‐section 11.09×31.22 Å2 along the a‐axis. Finally, 1 has been exploited as a heterogeneous catalyst for the ipso‐hydroxylation of arylboronic acids yielding up to 99 % of the respective phenolic product. Importantly, the catalyst can be reused for five successive cycles without having a significant loss in its catalytic efficiency.
Synthesis of chiral cyclodextrin metal‐organic framework modified with platinum on glassy carbon electrodes: Electrochemical chiral recognition of methionine enantiomers
Authors: Sun Xuezhi , Lin Chuhui , Ning Fanghong , Zhang Min , Fu Hua , Zhang Hongyang , Hu Ping 
Published: November 2022

AbstractA platinum nanoparticle‐modified chiral cross‐linked cyclodextrin MOF (Pt‐CLMOF) was synthesized. Then, a chiral electrochemical sensor was constructed using the Pt‐CLMOF nanomaterials for the recognition of methionine (Met) enantiomers and the chiral recognition mechanism was revealed by density functional theory calculations. The recognition effect of Pt‐CLMOF modified electrode (Pt‐CLMOF/GCE) on Met was studied by differential pulse voltammetry. The enantioselectivity coefficient (IL/ID) was 1.98. There is an acceptable linear relationship between peak current and Met enantiomer concentration in the 2–200 μM range, the detection limits of L–Met and D‐Met were 0.33 and 0.60 μM which were obtained by this electrochemical sensor, respectively. The synthesized materials were successfully applied to the analysis of Met enantiomers, indicating that Pt‐CLMOF materials have good application potentiality.
Calculation of the Tafel slope and reaction order of the oxygen evolution reaction between pH 12 and pH 14 for the adsorbate mechanism
Authors: Antipin Denis , Risch Marcel 
Published: November 2022

AbstractDespite numerous experimental and theoretical studies devoted to the oxygen evolution reaction (OER), the mechanism of the OER on transition metal oxides remains controversial. This is in part owing to the ambiguity of electrochemical parameters of the mechanism such as the Tafel slope and reaction orders. We took the most commonly assumed adsorbate mechanism and calculated the Tafel slopes and reaction orders with respect to pH based on microkinetic analysis using the steady‐state approximation. The analysis was performed for an ideal electrocatalyst without scaling of the intermediates as well as for one on the top of a volcano relation and one on each leg of the volcano relation which exhibits scaling of the intermediates. For these four cases, the number of possible Tafel slopes strongly depends on surface coverage. Furthermore, the Tafel slope becomes pH‐dependent when the coverage of intermediates changes with pH. These insights complicate the identification of a rate‐limiting step by a single Tafel slope at a single pH. Yet, simulations of reaction orders complementary to Tafel slopes can solve some ambiguities to distinguish between possible rate‐limiting steps. The most insightful information can be obtained from the low overpotential region of the Tafel plot. The simulations in this work provide clear guidelines to experimentalists for the identification of the limiting steps in the adsorbate mechanism using the observed values of the Tafel slope and reaction order in pH‐dependent studies.
A subcortical magnocellular pathway is responsible for the fast processing of topological properties of objects: A transcranial magnetic stimulation study
Authors: Wang Wenbo , Zhou Tiangang , Chen Lin , Huang Yan 
Published: November 2022

AbstractRapid object recognition has survival significance. The extraction of topological properties (TP) is proposed as the starting point of object perception. Behavioral evidence shows that TP processing takes precedence over other geometric properties and can accelerate object recognition. However, the mechanism of the fast TP processing remains unclear. The magnocellular (M) pathway is well known as a fast route to convey “coarse” information, compared with the slow parvocellular (P) pathway. Here, we hypothesize that the fast processing of TP occurs in a subcortical M pathway. We applied single‐pulse transcranial magnetic stimulation (TMS) over the primary visual cortex to temporarily disrupt cortical processing. Besides, stimuli were designed to preferentially engage M or P pathways (M‐ or P‐biased conditions). We found that, when TMS disrupted cortical function at the early stages of stimulus processing, non‐TP shape discrimination was strongly impaired in both M‐ and P‐biased conditions, whereas TP discrimination was not affected in the M‐biased condition, suggesting that early M processing of TP is independent of the visual cortex, but probably occurs in a subcortical M pathway. Using an unconscious priming paradigm, we further found that early M processing of TP can accelerate object recognition by speeding up the processing of other properties, e.g., orientation. Our findings suggest that the human visual system achieves efficient object recognition by rapidly processing TP in the subcortical M pathway.
Vaginal birth as compared with cesarean section in preterm twins—Experience from a tertiary center of a middle‐income country
Authors: Priyanka Palla , Abraham Kavitha , Navneetham Preethi , Abraham Anuja , Regi Annie 
Published: November 2022

AbstractObjectivesTo evaluate the mode of birth in early‐preterm, late‐preterm, and near‐term twins as well as to compare the maternal and neonatal outcomes of each group following vaginal birth (VB) and lower‐segment cesarean section (LSCS).MethodsA prospective cohort study was conducted of 100 twin pregnancies in a tertiary center between 2018 and 2019. Deliveries were allocated into the following three gestational age groups (weeks ± days) and compared: (1) early‐preterm (28 to 31 ± 6), (2) late‐preterm (32 to 35 ± 6), and (3) near‐term (≥36 weeks).ResultsThe proportion of VB and LSCS were similar when early‐preterm twins (P = 0.766; relative risk [RR], 1.08) and late‐preterm twins (P = 0.071; RR, 1.21) were compared separately with near‐term twins. Perinatal outcomes did not differ between VB and LSCS within each gestational age group. When compared with the near‐term group, the early‐preterm group had more hypoglycemia (P < 0.001), hyperbilirubinemia (P < 0.001), respiratory distress (P < 0.001), low APGAR scores (P < 0.001), and death (P < 0.001) irrespective of the mode of birth. The late‐preterm group had lower morbidity and mortality (P = 0.227). Postpartum hemorrhage and blood transfusion were similar between the groups.ConclusionThe proportion of VB and LSCS and associated maternal and neonatal outcomes did not differ in twins of different gestational ages. The data provide reassurance to practitioners to perform vaginal delivery in preterm twins.
GLP‐1 rescued gestational diabetes mellitus‐induced suppression of fetal thalamus development
Authors: You Longfei , Deng Yujie , Li Dan , Lin Yangyang , Wang Yuling 
Published: November 2022

AbstractDiabetes can be classified as type 1, type 2, and gestational diabetes mellitus (GDM). It has been reported that children born from mothers with GDM present motor impairment, however, underlying mechanisms of GDM‐induce fetal neurological diseases remain unknown. In this study, NOD (nonobese diabetic) mice were used to construct the GDM model; after 2 weeks of gestation, thalamocortical axon development of fetal was evaluated by immunofluorescence. PCR of LRRC4C was used to confirm axon development of the thalamus cortex. RNA array was used to predict possible targets affected by GDM during fetal neurodevelopment. Western blot was used to investigate the underlying mechanism, PI3K inhibitor, and MAPK inhibitor was used to determine key pathway involved in this model, in vitro axonal growth was evaluated using neural stem cells, tactile sensory behavior of offspring was assessed to confirm neurological influence further. The result shown that maternal diabetes significantly suppressed axonal development of fetal thalamus cortex, PCR array of GDM fetal brain indicated that upregulation of GLP‐1R compared with normal fetal, ELISA confirmed that GLP‐1 level was decreased in GDM maternal serum compared with that of wild type pregnant mice. In vitro study observed enhanced axonal elongation after supplements of GLP‐1 analog, GLP‐1 analog PI3K‐dependently active ROCK1 activity, IP injection of GLP‐1 analog could partly reverse GDM‐induced suppression of fetal thalamocortical axon development and improve tactile sensory behavior of GDM offspring. Our study provided a novel mechanism of GDM induced‐neurological diseases and predicted GLP‐1 as possible prevention supplement during gestation.
Low energy synthesis of anhydrite cement from waste lime mud
Authors: Kamarou Maksim , Moskovskikh Dmitry , Chan Ho Lun , Wang Haitao , Li Tielong , Akinwande Abayomi Adewale , Romanovski Valentin 
Published: November 2022

AbstractBackgroundThe re‐use of waste is the most important aspect of sustainable development for human health and environmental protection. Millions of tons of hazardous spent sulfuric acid and lime mud are produced by water treatment facilities every year. Unlike other types of waste, lime mud can sometimes be used for the thermal regeneration of lime. However, this approach requires a high energy consumption and, thus, cannot be considered a sustainable or green process. Compared to the latest research, the method presented here allowed for the production of anhydrite in one step at very low temperatures and in a short time while also bypassing the stage of gypsum phase formation.ResultsCalcium sulfate anhydrite was synthesized from the water treatment waste of lime mud by a low‐temperature method at temperatures of 25 and 45 °С. The resulting samples were composed of anhydrite with different crystal morphologies. This was confirmed by XRD, DTA, SEM, TEM, and thermochemical calculations. Dependences of the influence of the shape of crystals on the main technological properties of anhydrite cement and the influence of additives on the activation of the binding properties were established.ConclusionThe research shows that different types of calcium sulfate anhydrite require different additives and in different amounts. Introducing the optimal composition of additives‐activators made it possible to obtain anhydrite cement with a water‐anhydrite ratio of 0.25, an onset of setting no earlier than 40 min, an end of setting no later than 12 h, and a strength of 28.8 MPa. © 2022 The Authors. Journal of Chemical Technology and Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry (SCI).
Radical synthesis of dihydropyrano[2,3‐c]pyrazoles using acridine yellow G as a photo‐induced electron transfer photocatalyst
Authors: Mohamadpour Farzaneh 
Published: November 2022

AbstractWe developed a green method for the synthesis of dihydropyrano[2,3‐c]pyrazole scaffolds using Knoevenagel‐Michael tandem cyclocondensation of ethyl acetoacetate, hydrazine hydrate, aldehydes, and malononitrile. Acridine yellow G (AYG) was used as a photo‐induced electron transfer (photo‐induced electron transfer) photocatalyst via visible light as a sustainable energy source in an aqueous solution. This study is aimed at the development of an inexpensive and readily available non‐metal dye. With photochemically catalyzed AYG, yields are high, energy efficiency and environmental friendliness are present, as are significant atom economies, speed‐saving features, and ease of use. The result is that a wide range of chemical and environmental variables can be monitored over time. In this study, we calculated the turnover number (TON) and turnover frequency (TOF) of dihydropyrano[2,3‐c]pyrazole scaffolds.
A study of help‐seeking behaviors for African American men: Implications for counselor education
Authors: Shannon Jordan 
Published: November 2022

AbstractHistorically, stigma and help‐seeking intentions are largely seen as determinants on whether an individual uses professional counseling services. These constructs, however, have been understudied in African American men. Adopting a humanistic approach, this study revealed how the overarching constructs of stigma and help‐seeking intentions predicted whether African American men sought counseling. Logistic regression analyses of African American men (N = 119) confirmed stigma and help‐seeking intentions as predictors of counseling.
Predicting crop yields in Senegal using machine learning methods
Authors: Sarr Alioune Badara , Sultan Benjamin 
Published: November 2022

AbstractAgriculture plays an important role in Senegalese economy and annual early warning predictions of crop yields are highly relevant in the context of climate change. In this study, we used three main machine learning methods (support vector machine, random forest, neural network) and one multiple linear regression method, namely Least Absolute Shrinkage and Selection Operator (LASSO), to predict yields of the main food staple crops (peanut, maize, millet and sorghum) in 24 departments of Senegal. Three combination of predictors (climate data, vegetation data or a combination of both) are used to compare the respective contribution of statistical methods and inputs in the predictive skill. Our results showed that the combination of climate and vegetation with the machine learning methods gives the best performance. The best prediction skill is obtained for peanut yield likely due to its high sensitivity to interannual climate variability. Although more research is needed to integrate the results of this study into an operational framework, this paper provides evidence of the promising performance machine learning methods. The development and operationalization of such prediction and their integration into operational early warning systems could increase resilience of Senegal to climate change and contribute to food security.
Comprehensive evaluation of the Greenland halibut bone soup quality traits under different thermoultrasonic power
Authors: Bu Ying , Han Menglin , He Wei , Zhu Wenhui , Zhang Yuyu , Li Xuepeng , Li Jianrong , Zhang Yi 
Published: November 2022

AbstractBackgroundOur preliminary study proved that thermoultrasonic treatment (TUT) had a splendid optimization impact on the quality of halibut bone soup. To explore the effects of different ultrasonic power (100, 200, 300, 400, and 500 W) on the quality characteristics of halibut bone soup, the nutritional components, flavor, and micro nanoparticles (MNPs) traits were analyzed. Furthermore, comprehensive evaluation was implemented by the coefficient of variation method.ResultUsing ultrasonic power at 400 W resulted in a stable bone soup system with thick and milky white and increased migration of nutrients in soup. The contents of water‐soluble proteins, total sugar, and solids were 154.72 mg/100 ml, 18.29 mg/100 ml, and 3.07 g/100 ml, respectively. Simultaneously, the MNPs' particle size was 606.08 nm, and the particle size distribution was more concentrated. Besides, 5′‐nucleotides, organic acids, and other flavor substances in halibut bone broth were most abundant after the treatment of 400 W. The comprehensive score of halibut bone soup under 400 W treatment was the highest (28.16), obviously higher than those of other treatment groups.ConclusionTUT at 400 W can be used to produce high‐quality halibut bone soup and provide a reference for the rational application of fishbone by‐product processing.
Box‐Behnken assisted development and validation of high‐performance liquid chromatography method for the simultaneous determination of doxorubicin and vorinostat in polymeric nanoparticles
Authors: Sokol Maria , Gulyaev Ivan , Mollaeva Mariia , Kuznetsov Sergey , Zenin Vladimir , Klimenko Maksim , Yabbarov Nikita , Chirkina Margarita , Nikolskaya Elena 
Published: November 2022

While histone deacetylase inhibitors, such as vorinostat, demonstrate a significant effect against hematological cancers, their application for solid tumor treatment is limited. However, there is strong evidence that combinatorial administration of vorinostat and genotoxic agents (e.g., doxorubicin) enhances the antitumoral action of both drugs against tumors. We developed a high‐performance liquid chromatography method for the simultaneous determination of doxorubicin and vorinostat in polymeric nanoparticles designed to provide the parenteral administration of both drugs and increase their safety profile. We performed separation on Nucleodur C‐18 Gravity column with a mixture of 10 mM potassium dihydrogen phosphate buffer pH 3.9:ACN (90:10 v/v) as mobile phase at 240 nm. The method was linear within the concentration range of 4.2–52.0 μg/ml for both drugs with limits of detection and quantification of 3.5 and 10.7 μg/ml for doxorubicin and 2.5 and 7.7 μg/ml for vorinostat, respectively. The method was precise and accurate over the concentration range of analysis. Drug loading was 5.4% for doxorubicin and 0.8% for vorinostat. Degradation of doxorubicin after irradiation was less than 5%, while the amount of vorinostat decreased at 88% under the same conditions. Thus, the validated method could be adopted for routine simultaneous analysis of doxorubicin and vorinostat in polymeric nanoparticles.
Tympanostomy Tube Placement in Children with Autism Spectrum Disorder
Authors: Yan Flora , Shah Arnav , Isaacson Glenn 
Published: November 2022

ObjectiveThe frequency of tympanostomy tube (TT) placement among United States children with autism spectrum disorder (ASD) is not known. We explored the rate of TT placement in children with ASD in the United States and compared this to children without ASD. We further examined demographic and behavioral factors that might vary between the two groups.MethodsWe utilized data from the National Health Interview Survey (NHIS) administered in 2014. This survey samples a representative population of patients across the United States and includes children under 18 years of age. The 2014 version of the NHIS survey was chosen as it identifies both autism and TT placement among sampled patients. Descriptive statistics and univariable and multivariable logistic regression analyses were performed.ResultsIn total, 11,730 children (239 [2.0%] with ASD) were included. Overall, 34 (14.2%) children with ASD underwent TT placement versus 987 (8.6%) in children without ASD (p = 0.002) ASD diagnosis was associated with increased odds of TT placement (1.52 OR, 95% CI 1.04–2.22). Male sex, white race, and non‐Hispanic ethnicity were also associated with increased odds of TT placement. Age at the time of TT surgery was not different between those with versus without ASD.ConclusionChildren with ASD have an increased rate of TT placement compared to children without ASD. The reason(s) for this increased rate might include the following: higher rates of infection in ASD, over‐diagnosis of ear infection or hearing disability in a difficult‐to‐examine population, and/or a predilection toward aggressive treatment in this at‐risk group.Level of Evidence3‐National database study Laryngoscope, 133:2407–2412, 2023
Light and hydrologic connectivity drive dissolved oxygen synchrony in stream networks
Authors: Diamond Jacob S. , Pinay Gilles , Bernal Susana , Cohen Matthew J. , Lewis David , Lupon Anna , Zarnetske Jay , Moatar Florentina 
Published: November 2022

AbstractStream dissolved oxygen (DO) dynamics are an outcome of metabolic activity and subsequently regulate ecosystem functions such as in‐stream solute and sediment reactions. The synchronization of DO signals in and across stream networks is both a cause and effect of the mode and timing of these functions, but there is limited empirical evidence for network patterns of DO synchrony. We used high frequency DO measurements at 42 sites spanning five catchments and stream orders to evaluate DO signal synchrony in response to variation in light (a driver of photosynthesis) and discharge (a control on DO signal spatial extent). We hypothesized that stream network DO synchrony arises when regional controls dominate: when light inputs are synchronous and when longitudinal hydrologic connectivity is high. By complement, we predicted that DO signal synchrony decreases as light becomes more asynchronous and stream flows decline or become discontinuous. Our results supported this hypothesis: greater DO signal synchrony arose with increasing light synchrony and flow connectivity. A model including these two controls explained 70% of variation in DO synchrony. We conclude that DO synchrony patterns within‐ and across‐networks support the current paradigm of discharge and light control on stream metabolic activity. Finally, we propose that DO synchrony patterns are likely a useful prerequisite for scaling subdaily metabolism estimates to network and regional scales.
Influence of Temperature and Dose Rate of E‐Beam Modification on Electron‐Induced Changes in Polyacrylonitrile Fibers
Authors: Leopold Anne‐Katrin , Müller Michael Thomas , Zimmerer Cordelia , Bogar Mohsen Sadeghi , Richter Mirko , Wolz Daniel Sebastian , Stommel Markus 
Published: November 2022

AbstractThe present study investigates the influence of modification temperature and the dose rate of electron modification on the progress of these and the three important thermal induced reactions namely: cyclization, dehydrogenation, and oxidation. Since electron induced chemical reactions strongly depend on the polymer chain segment mobility, temperatures below the glass transition temperature (Tg) and above Tg are tested. Electron paramagnetic resonance (EPR) spectroscopy measurements show the presence of alkyl‐, peroxy‐, and polyimineradicals alongside each other. Gel measurements identified a temperature dependent crosslinking behavior at doses ⩽ 150 kGy, but no dose rate depending on crosslinking. Changes in chemical structure are investigated using Fourier transform infrared spectroscopy (FT‐IR), showing a dependency of stabilization behavior depending on dose and temperate more than on dose rate. Thermal gravimetric analysis (TGA) and differential scanning calorimetry (DSC) measurements complete the analyses by describing the behavior during further thermal treatments and measuring the residual mass at 800 °C.