bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical Signs, Laboratory Diagnosis and Treatments Involved in Corona Viruses-19
Authors: Israa Burhan Raoof  , Zahraa Ahmed Okhti  , Mayssaa E. Abdalah  
Published: April 2022

Covid -19 is a viral disease play important role in danger pathogens for human, it is infecting on respiratory, hepatic, central nervous systems and gastrointestinal, in addition to that, the triggers included cytokine storm is inflammatory response to viral infection

Therefore, excessive enhance of immune cells lead to new of pro-inflammatory cytokines. COVID-19 interaction with the cardiovascular system on different levels, rising death percent in people underlying cardiovascular state provoking myocardial injury. Respiratory infection varying from mild cold to the severe illness like as Middle East Respiratory Syndrome and Severe Acute Respiratory Syndrome the most important coronavirus (COVID-19) complications, however individuals with asymptomatic disease were also suspected of possible infectious transmission, which further adds to the uncertainty of the dynamic of disease transmission in COVID-19 infections, Suppression of angiotensin-converting enzyme (ACE2) expression by inflammatory cytokines accompanied by the decrease of estrogens and androgens of the elderly, establish a negative correlation between ACE2 expression and mortality in other cases may lead to infertility. Early detection by PCR has aided the identification of the pathogen at an early level. Furthermore, the treatment includes the effectiveness of glucocorticoid drugs (dexamethasone), anti-malaria drug (hydroxychloroquine), azithromycin (antibacterial drug) and favipiravir are all drugs recommended in illness with Covid-19. Remdesivir suppression COVID-19 replication and decreases viral load, alleviates clinical signs and improves pulmonary injury, therefore Remdesivir drug has been used as a compassionate medicine for treating COVID-19 patients.
Co-occurrence of Wilson disease and Auto-Immune Hepatitis in 14-year-old female: A case report
Authors: Fadwa Ghassan Hameed  , Inam Sameh Arif  , Mohammed Mahmood Mohammed  , Hala S. Arif  
Published: April 2022

Unusual cases of coexistence between Wilson's disease and autoimmune hepatitis have occurred. There are characteristics of both diseases in this community of patients, and laboratory and histo pathological findings can be misleading. Wilson disease's clinical appearance can differ widely; thus,
there is not always an easy diagnosis. In addition to being childhood and young adult illnesses, Wilson's disease can also be triggered at any age. Liver disease and cirrhosis, neuropsychiatric disorders, Kayser-Fleischer(KF.) rings, and acute hemolysis events are the primary characteristics of Wilson's disease, frequently in combination with acute liver failure. Diagnosis is extremely difficult for children and adults with active liver disease. None of the latest Wilson's disease laboratory tests are optimal and may not be specific. Therefore, by taking into account acute hepatitis similar to Wilson's disease and autoimmune hepatitis, concomitant treatment with immunosuppression and penicillamine may have a superior impact.
Nuclear Factor Erythroid-2 Linked Factor (Nrf2) as a Potential Mediator of Hepatotoxicity
Authors: Inam Sameh Arif  , Israa Burhan Raoof  , Hayder Hussein Luaibi  
Published: April 2022

Hepatotoxicity is a term used to describe serious health complications of liver disease caused by a variety of factors. Nuclear factor erythroid-2 linked factor (Nrf2) as a potential mediator of hepatotoxicity via inflammatory and induction of oxidative stress, oxidation
produces more toxic compounds caused more pathogenic cases; therefore, to maintain sufficient homeostasis, involve antioxidant materials and detoxification factors. Controlling cytokine activity in normal cells is a useful way to regulate the signaling pathway of Nrf2. Recent studies found a relation between each Nrf2 and NF-κB activation and drug-induced liver injury. This review presents a detailed and conformation update of Nrf2 roles in hepatotoxicity which considers that drug-induced liver injury is the main problem to draw attention in medical clinics and to develop new drugs with less harmful to the liver. In addition to that. Kept each of normal oxidation and cytokines levels is crucial responses for cells alteration and remaining to survive.
The Role Of Smart Leadership Dimensions In Crisis Management- A study For Opinions Of Sample Of Administrative Leaderships In A number Of Humanities Colleges At The University Of Mosul
Authors: Al-Jameel Reem Saad 
Published: April 2022

This research aims at answering many questions raised by the research problem concerning the view of the organizations under consideration for the concept of smart leadership and its most important dimensions, as well as the view of crisis management and its concept and most important methods through research objectives that define and clarify the smart leadership with its dimensions and methods of crisis management.
For the purpose of reaching the results of the research and testing the assumptions about the relationship between smart leadership and methods of crisis management, the researcher adopted a questionnaire, designed especially to be a criterion for the research, as the main tool for data collection. The results of the research sample, which consisted of (44) respondents from administrative leaders working in a number of humanities colleges at the University of Mosul, were analyzed, and important results were reached related to the existence of crisis management methods at the administrative leaders which work through smart leadership in the organization under consideration. The relation between the two variables was one of a strong correlation and the effect was significant between these two variables. The results confirmed the hypothesis of the research, and explanation of the role played by smart leadership in terms of its dimensions in crisis management in the researched field
Insulin Requirement and Complications Associated With Serum C-Peptide Decline in Patients With Type 1 Diabetes Mellitus During 15 Years After Diagnosis
Authors: Suh Junghwan , Lee Hae In , Lee Myeongseob , Song Kyungchul , Choi Han Saem , Kwon Ahreum , Kim Ho-Seong , Chae Hyun Wook 
Published: April 2022

ObjectiveC-peptide is conventionally used in assessing pancreatic function in patients with diabetes mellitus. The clinical significance of this molecule during the course of type 1 diabetes mellitus (T1DM) has been recently revisited. This study aimed to investigate the natural course of C-peptide in T1DM patients over the period of 15 years and analyze the association between the residual C-peptide and diabetes complications.MethodsThis retrospective study included a total of 234 children and adolescents with T1DM. Patient data including sex, age at diagnosis, anthropometric measures, daily insulin dose, serum HbA1c, post-prandial serum C-peptide levels, lipid profiles, and diabetic complications at the time of diagnosis and 1, 3, 5, 10, and 15 years after diagnosis were retrospectively collected.ResultsAmong the 234 patients, 101 were men and 133 were women, and the mean patient age at initial diagnosis was 8.3 years. Serum C-peptide decreased constantly since the initial diagnosis, and showed a significant decline at 3 years after diagnosis. At 15 years after diagnosis, only 26.2% of patients had detectable serum C-peptide levels. The subgroup with older patients and patients with higher BMI standard deviation score showed higher mean serum C-peptide, but the group-by-time results were not significant, respectively. Patients with higher serum C-peptide required lower doses of insulin and had fewer events of diabetic ketoacidosis.ConclusionSerum C-peptide decreased consistently since diagnosis of T1DM, showing a significant decline after 3 years. Patients with residual C-peptide required a lower dose of insulin and had a lower risk for diabetic ketoacidosis.
Artificial Feature Extraction for Estimating State-of-Temperature in Lithium-Ion-Cells Using Various Long Short-Term Memory Architectures
Authors: Kopp Mike , Ströbel Marco , Fill Alexander , Pross-Brakhage Julia , Birke Kai Peter 
Published: April 2022

The temperature in each cell of a battery system should be monitored to correctly track aging behavior and ensure safety requirements. To eliminate the need for additional hardware components, a software based prediction model is needed to track the temperature behavior. This study looks at machine learning algorithms that learn physical behavior of non-linear systems based on sample data. Here, it is shown how to improve the prediction accuracy using a new method called “artificial feature extraction” compared to classical time series approaches. We show its effectiveness on tracking the temperature behavior of a Li-ion cell with limited training data at one defined ambient temperature. A custom measuring system was created capable of tracking the cell temperature, by installing a temperature sensor into the cell wrap instead of attaching it to the cell housing. Additionally, a custom early stopping algorithm was developed to eliminate the need for further hyperparameters. This study manifests that artificially training sub models that extract features with high accuracy aids models in predicting more complex physical behavior. On average, the prediction accuracy has been improved by ΔTcell=0.01 °C for the training data and by ΔTcell=0.007 °C for the validation data compared to the base model. In the field of electrical energy storage systems, this could reduce costs, increase safety and improve knowledge about the aging progress in an individual cell to sort out for second life applications.
المركب الإضافي والمركب الوصفي في سورة الكهف
Authors: Kausari Ahmad , Qomariah Lailatul , Deviana Ade Destri 
Published: April 2022

<div class="WordSection1"><p style="text-align: justify;"><em>Kaidah tentang frasa idhafah dan frasa sifat termasuk kaidah tata bahasa Arab yang sering digunakan dalam bahasa Arab,</em><em> </em><em>keduanya merupakan perkara sangat sangat pe</em><em>n</em><em>ting dalam tata bahasa Arab. </em><em>Namun, </em><em>masih banyak pembelajar yang kesulitan dalam memahami, menentukan, dan membedakan keduanya. Penelitian ini diharapakan bisa memb</em><em>a</em><em>ntu </em><em>pembelajar</em><em> dalam memaha</em><em>mi dua kaidah tersebut. Penelitian ini bertujuan untuk mengetahui frasa idhafah dan frasa sifat di surah al-kahfi serta jenis-jenisnya. Adapun jenis penelitian ini adalah penelitian literatur (library research) dengan pendekatan kualitatif. Teknik analisa data yang digunakan ialah teknik analisis konten (content analysis). Hasil penelitian ini adalah: (1) Pada surah al-kahfi terdapat 250 frasa idhafah yang tersebar di 95 ayat dan 63 frasa sifat yang tersebar di 38 ayat. (2) Jenis-jenis frasa idhafah yang terdapat pada surah al-kahfi ada 7 jenis, yaitu: idhafah lafzhiyyah, idhafah ma’nawiyyah, idhafah dengan taqdir huruf lam, idhafah dengan taqdir huruf min, idhafah dengan taqdir huruf fi, idhafah yang mudhaf ilaihnya mufrad, dan idhafah yang mudhaf ilaihnya jumlah. Adapun jenis-jenis </em><em>frasa sifat yang terdapat pada surah al-kahfi ada 5 jenis, yaitu: na’at haqiqi, na’at sababi, na’at mufrad, na’at jumlah, na’at syibh al-jumlah.</em></p></div>
Implementasi Komunikasi Model Penta Helix untuk Meningkatkan Pendidikan Agama Islam
Authors: Sulaeman Sulaeman , Rohman Hakim Arif , Syahman Maman , Ma’mun Ma’mun , Ruspandi Tatang , Yoyoh Yoyoh 
Published: April 2022

Pendidikan Islam harus mampu menghaluskan perasaan, mengubah sikap manusia menjadi lebih peka dan peduli, lebih inklusif, lebih toleran, lebih pluralistik, dan lebih humanis serta lebih peduli terhadap kelestarian lingkungan dan alam semesta. Berdasarkan hasil survey di desa Balong terdapat salah satu dusun yaitu Dusun Pamijen yang tingkat pendidikan keagamaannya kurang berkembang, ada satu lembaga pendidikan keagamaan yang cukup permanen namun tidak difungsikan, begitu pula dengan masjid hanya digunakan tempat shalat, tidak ada kegiatan pendidikan khususnya pendidikan anak-anak seperti di masjid-masjid lain.hal ini dimungkinkan kurangnya perhatian dari pemerintah desa dan kurangnya komunikasi serta koordinasi antar tokoh masyarakat. Oleh karena itu, pengabdian ini bertujuan untuk bisa membantu bagaimana menumbuhkan pola komunikasi antara pemerintah dengan masyarakat khususnya para tokoh agama agar pendidikan agama bisa berkembang. Pengabdian ini menggunakan pendekatan Participatory Action Research (PAR). Pendekatan ini dimaksudkan untuk melihat, mendengar, dan juga memahami fenomena sosial yang ada pada masyarakat Dusun Pamijen , desa Balong. Pengabdian ini adalah untuk Membangun komunikasi antar tokoh masyarakat, baik dari pemerintah daerah, tokoh agama, maupun tokoh masyarakat untuk memajukan kegiatan keagamaan di masyarakat yang berdampak pada kurangnya interaksi dan kerjasama yang menghambat perkembangan kegiatan keagamaan. Kehadiran Mahasiswa Pascasarjana Universitas Islam Al-Ihya Kuningan Khusus nya kelompok 4 dalam pelaksanaan Pengabdian Kepada Masyarakat memberikan solusi untuk mereka agar bisa berkomunikasi dengan baik, dalam rangka menyamakan persepsi untuk meningkatkan pemahaman keagamaan.
Pengaruh Kualitas Website Traveloka Menggunakan Webqual 4.0 Terhadap Kepuasan Pengguna
Authors: Sari Maulidah Nur Komala , Utamajaya Joy Nashar 
Published: April 2022

Traveloka adalah sebuah perusahaan reservasi tiket pesawat dan hotel di mana pengguna dapat melakukan pemesanan pada situs Traveloka.com. Traveloka menggunakan konsep pemasaran berbasis online melalui website sebagai sarana mengkomunikasikan produk-produk perusahaan kepada publik. Penelitan ini bertujuan untuk mengetahui pengaruh kualitas website terhadap kepuasan pengguna khususnya di Komunitas traveloka di sosial media Telegram menggunakan metode webqual 4.0 yang memiliki 3 dimensi yaitu kualitas kegunaan, kualitas informasi, dan kualitas interaksi. Penelitian ini dilakukan menggunakan penelitian kuantitatif dengan jumlah responden 85 responden. Hasil penelitian ini berdasarkan uji F menunjukkan hasil nilai Fhitung yaitu (43,105) > F Tabel (2,72) maka H0 ditolak, dan Ha diterima. Sehingga kualitas kegunaan (X1), informasi (X2) dan interaksi (X3) secara simultan berpengaruh terhadap variabel kepuasan konsumen (Y). Kemudian untuk nilai t hitung untuk kualitas kegunaan (1,785) > nilai t tabel 1,990 tidak berpengaruh secara signifikan terhadap kepuasan konsumen di Traveloka. Nilai t hitung untuk informasi (2,050) > nilai t tabel 1,990 yang artinya kualitas informasi berpengaruh secara signifikan terhadap kepuasan konsumen di Traveloka. Kemudian, nilai t hitung untuk interaksi (1,501) > nilai t tabel 1.990 artinya kualitas interaksi tidak berpengaruh secara signifikan terhadap kepuasan konsumen di Traveloka.
Peningkatan Motivasi Belajar Siswa Kelas X Ipa Menggunakan Geogebra Pada Materi Trigonometri
Authors: Yanti Fitri , Agustina Wiwik , M. Biomed M. Biomed , Yekti Mumpuni Risma 
Published: April 2022

LatarBelakang: Berdasarkan hasil pengalaman mengajar materi trigonometri diketahui bahwa motivasi belajar sebagian besar siswa X IPA SMAN 3 Sanggau sangat rendah.
Tujuan: Tujuan penelitian ini adalah peningkatkan motivasi belajar siswa X IPA materi Trigonometri melalui GeoGebra. Metode: Metode penelitian ini adalah penelitian tindakan kelas. Pengumpulan data melalui non tes. Teknik non tes digunakan untuk mengetahui perkembangan motivasi belajar dengan menggunakan lembar pengamatan. Untuk mengetahui peningkatan motivasi digunakan analisis deskriptif kualitatif. Hasil: Hasil penelitian tindakan kelas ini menunjukkan peningkatan motivasi belajar siswa dari rendah menjadi tinggi sehingga menurut teoritik dan empirik menggunakan GeoGebra pada materi Trigonometri dapat meningkatkan motivasi belajar siswa X IPA SMA Negeri 3 Sanggau semester genap tahun 2021/2022. Kesimpulan: Teoritik dan empirik dengan menggunakan
GeoGebra dapat meningkatkan motivasi belajar matematika materi Trigonometri bagi siswa kelas X IPA SMA Negeri 3 Sanggau semester genap tahun 2021/2022.
Pengembangan Produk Pangan Olahan dari Pala di Desa Pasie Kuala Asahan
Authors: Riza Cut Lena , Yuliani Hilka 
Published: April 2022

LatarBelakang: Minimnya pemanfaatan daging buah pala menyebabkan daging buah pala sering terbuang sebagai limbah. Padahal jika dimanfaatkan secara optimal melalui diversifikasi produk olahan, buah pala dapat menghasilkan produk yang bernilai ekonomi sehingga berpeluang meningkatkan pendapatan petani pala. Tujuan: Penelitian ini bertujuan untuk mengembangkan produk olahan pala yaitu sukade dan sari pala serta mengetahui penerimaan produk tersebut berdasarkan uji organoleptik. Metode: Penelitian dilaksanakan dengan pengujian hedonik pada sukade pala, dan sari pala menggunakan pembanding sukade pepaya dan sari nenas. Variabel pengamatan meliputi tingkat kesukaan panelis/organoleptik (warna, aroma, dan rasa). Data yang terkumpul dianalisis secara statistik dan dilanjutkan menggunakan uji beda BNT dalam tingkat 5%. Hasil: Hasil penelitian terkait tingkat kesukaan panelis terhadap sukade pala menggunakan pembanding sukade pepaya menunjuk skor penilaian warna (5,2-5,4) kategori agak suka, rasa (5,1-5,5) kategori agak suka, aroma (5,4-5,7) kategori agak suka hingga suka, dan tekstur (4,3-4,8) termasuk kategori netral hingga agak suka. Hasil pengujian organoleptik pada sari pala dengan pembanding sari nenas diperoleh skor penilaian warna (4,7-4,9) kategori agak suka, rasa (5,7-5,9) kategori suka, dan aroma (5,6-5,8) kategori suka. Secara organoleptik dapat diketahui bahwa perbandingan antara sukade pala dengan sukade pepaya serta sari pala dengan sari nenas tidak berbeda nyata sehingga dapat dijadikan sebagai produk alternatif pala. Kesimpulan: Secara organoleptik dapat diketahui bahwa perbandingan antara sukade pala dengan sukade pepaya serta sari pala dengan sari nenas tidak berbeda nyata sehingga dapat dijadikan sebagai produk alternatif pala.
Perspektif Hukum: Penjaminan Simpanan pada Perbankan Syariah
Authors: Nabillah Anindya , Harrieti Nun , Nova Lita Helza 
Published: April 2022

LatarBelakang: Likuidasi yang terjadi pada 16 bank di Indonesia berdampak terhadap tingkat kepercayaan masyarakat sebagai nasabah. Peristiwa ini menjadi alasan pemerintah mengeluarkan kebijakan baru dalam perbankan yaitu dengan memberikan jaminan atas simpanan setiap nasabah. Tujuan: Penelitian ini bertujuan untuk mewujudkan usaha yang dapat mendukung pembangunan ekonomi pada industri perbankan yang dipercaya oleh masyarakat sebagai lembaga untuk menyimpan dana dan LPS untuk menjamin simpanan nasabah. Metode: Metode penelitian yang dipakai dalam tulisan ini adalah yuridis normatif yang dilakukan dengan cara meneliti permasalahan dan mengaitkan dengan hukum positif dan metode analisisnya adalah metode deskriptif. Hasil: Hasil penelitian menunjukkan Pemberian jaminan kepada nasabah dilakukan dengan cara membuka fasilitas yang ditentukan bank yang terlebih dahulu menganalisa dan melakukan evaluasi nasabah yang akad diberi jaminan. Secara terperinci LPS Syariah memang belum memiliki aturan tersendiri, namun dalam melaksanakan penjaminan LPS sudah menerapkan sejalan dengan ajaran syariah. Kesimpulan: Keberadaan perbankan yang sudah lama menjadi pusat industri perputaran ekonomi suatu negara, harus mempertahankan kepercayaan seluruh nasabah yang mempercayai industri perbankan dalam menyimpan aset dan harta kekayaannya.
Evaluation of efficacy and failure of high flow nasal cannula therapy in paediatric emergency service and paediatric intensive care unit
Authors: İleri Gizem , Zengin Neslihan , Bal Alkan 
Published: April 2022

Objective: High-flow nasal cannula oxygen therapy (HFNC) improves gas exchange and decreases work of breathing in patients with acute respiratory distress. We aimed to discuss the indications for HFNC in children of all ages and diagnoses and to evaluate the efficacy and risk factors for failure of HFNC therapy in children with acute respiratory distress and failure in a paediatric emergency service and paediatric intensive care unit (PICU).
Material and Methods: A total of 191 patients aged one month to 18 years treated with HFNC between October 1, 2018, and July 1, 2020, in the Paediatric Emergency Service and PICU were included in the study. Demographic and clinical characteristics, underlying chronic diseases, HFNC treatment success, and treatment failure of the cases were recorded.
Results: One hundred ninety-one children were included in the study, of whom 70 (36.6%) were female, and the median age was 13 months (1-204). The most common indication of HFNC treatment was bronchopneumonia (n=83, 43,5 %). HFNC treatment succeeded in 81.7 % (n=156) of the patients. It was observed that the two most successful patient groups were acute bronchiolitis and pneumonia. The failure rate was 18.3 % (35 of 191 children). The most common underlying comorbidity was bronchopulmonary dysplasia (BPD) (19, 9.9%). There was a statistically significant difference seen on Glasgow Coma Scale (GCS) and lactate value in blood gas in the first hour of the treatment in the group with unsuccessful results (p<0.05). During the HFNC treatment, 28 patients (14.7%) required invasive mechanical ventilation (IMV), and seven patients (3.7%) required non-invasive mechanical ventilation (NIMV).
Conclusion: HFNC is a reliable non-invasive treatment modality that is easily tolerated by children and has effective use in many critical diseases. Our study found that HFNC therapy could be initiated as the first-line therapy for various aetiologies of acute respiratory distress in a paediatric emergency service and PICU and all age groups. It was emphasized that transition to other treatment modalities should not be delayed in the cases predicted to be unsuccessful.