bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH GAYA KEPEMIMPINAN, MOTIVASI DAN KEPUASAN KERJA TERHADAP KINERJA GURU (STUDI KASUS PADA SMK NEGERI 1 SIMPANG MAMPLAM KABUPATEN BIREUEN)
Authors: Fatah Fatah , Ilyas Moch 
Published: February 2022

Tujuan penelitian ini adalah untuk mengetahui dan menganalisis; a) pengaruh gaya kepemimpinan terhadap kinerja guru, b) pengaruh motivasi terhadap kinerja guru, c) pengaruh kepuasan kerja terhadap kinerja guru, dan d) pengaruh secara simultan gaya kepemimpinan, motivasi, kepuasan kerja berpengaruh terhadap kinerja guru. Penelitian dilakukan di SMK Negeri 1 Simpang Mamplam Kabupaten Bireuen, dengan jenis penelitian deskriptif dan eksplanatori yang menjelaskan hubungan kausal dan pengaruh antar variabel melalui pengujian hipotesis, dengan metode analisis dengan pendekatan analisi jalur. Secara dsekriptif, diperoleh, a). Faktor gaya kepemimpinan, menurut persepsi guru sudah baik, mencapai 83,19% walaupun masih harus dioptimalkan lagi. b). Faktor motivasi dianggap oleh sebagain guru sudah baik dalam mendukung kinerja guru. Skor penilaian guru atas motivasi mencapai 81,04 %, c). Faktor kepuasan kerja, menurut penilaian guru, juga hampir mendekati optimal, yaitu mencapai 81,66%, dan d). Tingkat Kinerja guru mencapai kategori baik, yakni 81,29 %. Sedangkan secara eksplanatori, diperoleh hasil bahwa; 1).pengaruh faktor Gaya kepemimpinan terhadap Kinerja guru sebesar 24,53%, 2).pengaruh faktor Motivasi terhadap Kinerja guru sebesar 19,12%, 3) pengaruh Kepuasan kerja terhadap Kinerja guru di SMK Negeri 1 Simpang Mamplam Kabupaten Bireuen, yakni sebesar, yakni sebesar 16,95%.
Leidraad Duurzaamheidsafspraken: een stap in de goede richting?
Authors: Koeman A.A. , Koeman N.S.J. 
Published: February 2022

Leidraad Duurzaamheidsafspraken: een stap in de goede richting? De (on)mogelijkheden binnen het mededingingsrecht op het gebied van duurzaamheidsafspraken volgens de Autoriteit Consument & Markt en de Europese Commissie. Wie heeft gelijk?
De Leidraad Duurzaamheidsafspraken van de Autoriteit Consument & Markt is op 21 januari 2021 gepresenteerd en zal nu gebruikt worden in de discussies met de Europese Commissie over het onderwerp mededinging en duurzaamheid. In dit artikel worden de inhoud van de Leidraad Duurzaamheidsafspraken en de visie van de Europese Commissie op duurzaamheidsafspraken besproken. Door het artikel heen geven de auteurs hun mening over de verschillen tussen beide visies en of hiermee de bestaande problemen worden opgelost.Autoriteit Consument & Markt, Leidraad Duurzaamheidsafspraken, 26 januari 2021, www.acm.nl/nl/publicaties/leidraad-duurzaamheidsafspraken-gereed-voor-verdere-europese-afstemming.
De Handels- en Samenwerkingsovereenkomst tussen de EU en het VK: partnerschap of conflictbeheersing?
Authors: Larik J.E. , Wessel R.A. 
Published: February 2022

De Handels- en Samenwerkingsovereenkomst tussen de EU en het VK: partnerschap of conflictbeheersing?
De Handels- en samenwerkingsovereenkomst tussen de Europese Unie (en Euratom) en het Verenigd Koninkrijk is ondertekend op 30 december 2020 en op 1 mei 2021 formeel in werking getreden. Terwijl het Terugtrekkingsakkoord tussen de Europese Unie en het Verenigd Koninkrijk kan worden gezien als de ‘echtscheidingsovereenkomst’, die voornamelijk alle kwesties behandelt die verband houden met een ordelijke uittreding van het Verenigd Koninkrijk, legt de Handels- en samenwerkingsovereenkomst de basis voor een nieuwe relatie tussen de twee partijen. Deze relatie is niet langer gebaseerd op een lidmaatschap dat wordt bepaald door de supranationale rechtsorde van de Europese Unie, maar op een pragmatisch partnerschap op basis van internationaal publiekrecht, of, zoals sommige Britse vertegenwoordigers blijven benadrukken, een relatie tussen ‘soevereine gelijken’.Handels- en Samenwerkingsovereenkomst tussen de Europese Unie en de Europese Gemeenschap voor Atoomenergie, enerzijds, en het Verenigd Koninkrijk van Groot-Brittannië en Noord-Ierland, anderzijds (PbEU 2021, L 149/10). Besluit (EU) 2021/689 van de Raad van 29 april 2021 betreffende de sluiting, namens de Unie, van de Handels- en samenwerkingsovereenkomst tussen de Europese Unie en de Europese Gemeenschap voor Atoomenergie, enerzijds, en het Verenigd Koninkrijk van Groot-Brittannië en Noord-Ierland, anderzijds, en van de Overeenkomst tussen de Europese Unie en het Verenigd Koninkrijk van Groot-Brittannië en Noord-Ierland inzake beveiligingsprocedures voor de uitwisseling en bescherming van gerubriceerde gegevens (PbEU 2021, L 149/2).
Reimaginar el tiempo de la condición póstuma. Una aproximación desde la activación del esquema «“¿y si…?” — “entonces”» en cuanto thought experiment
Authors: Boqué Marc 
Published: February 2022

En tiempos en los que el relato dominante se fundamenta en una alerta global permanente, nuestra imaginación entra en crisis. El «¿y si…?» amenazante la dirige hacia un «entonces» donde, por un lado, reside el apocalipsis y, por el otro, la tecnoutopía. En ambos casos, esta imaginación se proyecta hacia un futuro en el que los humanos dejamos de intervenir sobre nuestras condiciones de vida y, por tanto, queda alejada de cualquier tipo de experimentación con el presente. Pero ¿cómo desanclar esta imaginación de la necesidad que implica la evolución predecible de nuestra realidad actual? ¿Cómo desligarla de sus miedos, su devastación o su precariedad?
En este artículo, investigamos la relación que guarda la imaginación con el experimento mental a partir del análisis de los ejemplos que nos proporcionan el aforismo 341 de La gaya ciencia de Nietzsche, el desarrollo de la teoría relatividad especial de Einstein y la película Memento de Christopher Nolan. Todos ellos se presentan bajo el triple sentido que Nietzsche dio al termino Versuch. Es decir, como ensayos, probaturas y tentativas que, en este caso, tendrán la función de reinterpretar la condición lineal y absoluta del tiempo. Los resultados de estos experimentos nos tendrán que servir en la última parte de nuestro trabajo para habilitar las condiciones que una imaginación colectiva debería tener actualmente para ser revulsiva ante el tiempo que proclama nuestra condición póstuma.
Climate in Africa sequentially shapes spring passage of Willow WarblerPhylloscopus trochilusacross the Baltic coast
Authors: Remisiewicz Magdalena , Underhill Les G. 
Published: February 2022

BackgroundMany migrant birds have been returning to Europe earlier in spring since the 1980s. This has been attributed mostly to an earlier onset of spring in Europe, but we found the timing of Willow Warblers’ passage to be influenced by climate indices for Africa as much as those for Europe. Willow Warblers’ spring passage through northern Europe involves populations from different wintering quarters in Africa. We therefore expected that migration timing in the early, middle and late periods of spring would be influenced sequentially by climate indices operating in different parts of the winter range.MethodsUsing data from daily mistnetting in 1 April–15 May over 1982–2017 at Bukowo (Poland, Baltic Sea coast), we derived an Annual Anomaly (AA, in days) of Willow Warbler spring migration. We decomposed this anomaly into three main periods (1–26 April, 27 April–5 May, 6–15 May); one-third of migrants in each period. We modelled three sequential time series of spring passage using calendar year and 15 large-scale climate indices averaged over the months of Willow Warblers’ life stages in the year preceding spring migration as explanatory variables in multiple regression models. Nine climate variables were selected in the best models. We used these nine explanatory variables and calculated their partial correlations in models for nine overlapping sub-periods of AA. The pattern of relationships between AA in these nine sub-periods of spring and the nine climate variables indicated how spring passage had responded to the climate. We recommend this method for the study of birds’ phenological responses to climate change.ResultsThe Southern Oscillation Index and Indian Ocean Dipole in Aug–Oct showed large partial correlations early in the passage, then faded in importance. For the Sahel Precipitation Index (PSAH) and Sahel Temperature Anomaly (TSAH) in Aug–Oct partial correlations occurred early then peaked in mid-passage; for PSAH (Nov–March) correlations peaked at the end of passage. NAO and local temperatures (April–May) showed low correlations till late April, which then increased. For the Scandinavian Index (Jun–Jul) partial correlations peaked in mid-passage. Year was not selected in any of the best models, indicating that the climate variables alone accounted for Willow Warblers’ multiyear trend towards an earlier spring passage.DiscussionClimate indices for southern and eastern Africa dominated relationships in early spring, but western African indices dominated in mid- and late spring. We thus concluded that Willow Warblers wintering in southern and eastern Africa dominated early arrivals, but those from western Africa dominated later. We suggest that drivers of phenological shifts in avian migration are related to changes in climate at remote wintering grounds and at stopovers, operating with climate change in the north, especially for species with complex and long-distance migration patterns.
Recursive Bayesian inference and learning for target tracking with unknown maneuvers
Authors: Ji Ruiping , Liang Yan , Xu Linfeng 
Published: February 2022

SummaryThis paper addresses the problem of target tracking under completely unknown maneuvering behavior to cope with the complicated target maneuvers. The actual but unknown motion model is formulated as a linear stochastic model with unknown transition matrix and modeling error covariance. Considering the diversity and time‐varying of maneuvers, both the transition matrix and covariance are random. Accordingly, the tracker design amounts to recursively updating the joint posterior of target state and unknown parameters (i.e., the transition matrix and covariance). Since it is difficult to obtain the analytical joint posterior, a Bayesian inference and learning scheme is proposed in the sequential Monte Carlo (SMC) framework to alternatively update the state posterior and the unknown parameters posterior. Particularly, it is revealed that the state prediction density used in the SMC obeys a Student's t‐distribution, thus ensuring the effective sampling of particle trajectories. Finally, a maneuvering benchmark shows that the proposed tracker can significantly reduce the peak tracking error, which is one of the most important performance indices for preventing tracking failure.
Grazed perennial grasslands can match current beef production while contributing to climate mitigation and adaptation
Authors: Jackson Randall D. 
Published: February 2022

AbstractThe U.S. grain‐finished beef system is highly productive but has many negative consequences for human health and well‐being because it pollutes surface and groundwaters, exacerbates flooding, reduces biodiversity, and contributes to climate change. Moving the entire U.S. grain‐fed beef production system to a grass‐finished system is possible without displacing food production and under conservative soil carbon (C) change estimates would result in a reduced but similar C footprint, while improving soil health, water quality, and biodiversity. More optimistic estimates for soil C accumulation indicate the system would result in significant atmospheric C drawdown. Agroecological transformation like this is limited only by our imagination and policies that incentivize agriculture for the public good rather than profits for a few.
Safety and efficacy of a humanized CD19 chimeric antigen receptor T cells for relapsed/refractory acute lymphoblastic leukemia
Authors: Shi Ming , Li Li , Wang Shiyuan , Cheng Hai , Chen Wei , Sang Wei , Qi Kunming , Li Zhenyu , Wang Gang , Li Huizhong , Lan Jianping , Huang Jinqi , Fei Xiaoming , Yu Min , Li Fei , Qiao Jianlin , Wu Qingyun , Zeng Lingyu , Jing Guangjun , Zheng Junnian , Gale Robert Peter , Xu Kailin , Cao Jiang 
Published: February 2022

AbstractCD19‐targeted chimeric antigen receptor T (CAR‐T) cells using murine single‐chain variable fragment (scFv) has shown substantial clinical efficacy in treating relapsed/refractory acute lymphoblastic leukemia (R/R ALL). However, potential immunogenicity of the murine scFv domain may limit the persistence of CAR‐T cells. In this study, we treated 52 consecutive subjects with R/R ALL with humanized CD19‐specific CAR‐T cells (hCART19s). Forty‐six subjects achieved complete remission (CR) (N = 43) or CR with incomplete count recovery (CRi) (N = 3) within 1 month post infusion. During the follow‐up with a median time of 20 months, the 1‐year cumulative incidence of relapse was 25% (95% confidence interval [CI] 13–46), and 1‐year event‐free survival was 45% (95% CI 29–60). To the cutoff date, 20 patients presented CD19+ relapse and 2 had CD19− relapse. Among the 22 relapsed patients, 14 had treatment‐mediated and treatment‐boosted antidrug antibodies (ADA) as detected in a sensitive and specific cell‐based assay. ADA positivity was correlated with the disease relapse risk. ADA‐positive patients had a significantly lower CAR copy number than ADA‐negative patients at the time of recurrence (p < .001). In conclusion, hCART19s therapy is safe and highly active in R/R ALL patients, and the hCART19s treatment could induce the emergence of ADA, which is related to the recurrence of the primary disease.
Is age of menarche directly related to vitamin D levels?
Authors: Al‐Taiar Abdullah , Al‐Sabah Reem , Shaban Lemia , Sharaf Alddin Reem , Durgampudi Praveen K. , Galadima Hadiza 
Published: February 2022

AbstractIntroductionVery few studies have examined the direct link between age of menarche and vitamin D level and controversial results have been reported. This study aimed to investigate the association between vitamin D and age of menarche in a group of adolescent girls in an area with plenty of sunshine.MethodsAt baseline, data were collected on 722 middle schoolgirls that were randomly selected by probability proportional to size sampling method. Of this group, 598 were followed including 173 who had their menarche during the follow‐up. Serum 25‐hydroxyvitamin D (25OHD) was measured at baseline using liquid chromatography‐tandem mass spectrometry (LC‐MS/MS). Data on potential confounders were collected at baseline from the parents using self‐administered questionnaire and from schoolgirls through face‐to‐face interview. Multiple linear regression and time‐to‐event analysis were used to investigate the association between 25OHD concentration and age of menarche.ResultsThe mean (SD) age of the study group was 12.51 (0.91) years while the main (SD) age of menarche was 11.82 (1.04) years. The prevalence of vitamin D deficiency (<50 nmol/L) among schoolgirls was 91.69%. We found no evidence for the association between 25OHD levels and age of menarche before (β, .00, 95% confidence interval (CI) [−0.01, 0.01]; p = .808) or after (β, .00, 95% CI [−0.01, 0.01]; p = .765) adjusting for potential confounders. We also found no evidence for association between 25OHD status and age of menarche before (p = .424) or after (p = .356) adjusting for potential confounders. Time‐to‐event analysis showed no association between 25OHD level or status and age of menarche (p = .850).ConclusionIn Middle Eastern setting, where vitamin D deficiency is common despite plenty of sunshine, vitamin D is not a major determinant of the age at menarche. Regardless of the link between vitamin D and age of menarche, there are several other health benefits of having adequate vitamin D level during childhood and adolescence.
Location, symptoms, and management of plexiform neurofibromas in 127 children with neurofibromatosis 1, attending the National Complex Neurofibromatosis 1 service, 2018–2019
Authors: Collins‐Sawaragi Yoshua Colyn , Ferner Rosalie , Vassallo Grace , De Agrò Germana , Eccles Simon , Cadwgan Jill , Hargrave Darren , Hupton Eileen , Eelloo Judith , Lunt Lauren , Tang Vivian , Burkitt Wright Emma , Lascelles Karine 
Published: February 2022

AbstractWe report on the location, symptoms, and management of plexiform neurofibroma (PN) in children with Neurofibromatosis Type 1 (NF1) attending the 2 National Complex Neurofibromatosis 1 Services at Guy's and St. Thomas' NHS Foundation Trust, London and St Mary's Hospital, Manchester. Retrospective data collection was performed from patient chart reviews from April 2018 to April 2019. There were 127 NF1 patients with PN, age range 0.8–17.0, mean age was 9.9 years (SD ± 4.2 years). The main location of the PN was craniofacial in 35%, and limb in 19%. Disfigurement was present in 57%, pain in 28%, impairment of function in 23%, and threat to function in 9% of children. Fifty‐four percent of patients were managed conservatively, 28% surgically, and 19% are either taking or due to start a mitogen‐activated protein kinase kinase (MEK) inhibitor (selumetinib or trametinib), either through a clinical trial or compassionate usage scheme. This national study provides a comprehensive overview of the management of children with PN in an era where new therapies (MEK inhibitors) are becoming more widely available. We anticipate that there will be a shift to more patients receiving MEK inhibitor therapy and combination therapy (surgery and MEK inhibitor) in the future.
Analysis of induced pluripotent stem cell clones derived from a patient with mosaic neurofibromatosis type 2
Authors: Ishi Yukitomo , Era Takumi , Yuzawa Sayaka , Okamoto Michinari , Sawaya Ryosuke , Motegi Hiroaki , Yamaguchi Shigeru , Terasaka Shunsuke , Houkin Kiyohiro , Fujimura Miki 
Published: February 2022

AbstractThe diagnosis of mosaicism is challenging in patients with neurofibromatosis type 2 (NF2) subset due to low variant allele frequency. In this study, we generated induced pluripotent stem cells (iPSCs) were generated from a patient clinically diagnosed with NF2 based on multiple schwannomas, including bilateral vestibular schwannomas and meningiomas. Genetic analysis of the patient's mononuclear cells (MNCs) from peripheral blood failed to detect NF2 alteration but successfully found p.Q65X (c.193C>T) mutation in all separate tumors with three intracranial meningiomas and one intraorbital schwannoma, and confirming mosaicism diagnosis in NF2 alteration using deep sequencing. Five different clones with patient‐derived iPSCs were established from MNCs in peripheral blood, which showed sufficient expression of pluripotent markers. Genetic analysis showed that one of five generated iPSC lines from MNCs had the same p.Q65X mutation as that found in NF2. There was no significant difference in the expression of genes related to NF2 between iPSC clones with the wild‐type and mutant NF2. In this case, clonal expansion of mononuclear bone marrow‐derived stem cells recapitulated mosaicism's genetic alteration in NF2. Patient‐derived iPSCs from mosaic NF2 would contribute to further functional research of NF2 alteration.
Molecular synergistic synthesis of AIPO‐18 zeolite‐stabilized Pt nanocatalysts with high dispersion for the hydrogenation of levulinic acid to γ‐valerolactone
Authors: Wang Yanyun , Zhou Yuming , Bao Jiehua , Wang Jiajia , Zhang Yiwei , Sheng Xiaoli , Huang Yuzhong 
Published: February 2022

AbstractPt nanocatalysts have received enthusiastic attention in the field of clean energy technologies due to their high catalytic activity and selectivity. The growth size and dispersion of Pt particles play significant effects on the reaction activity, especially in high temperature catalytic reactions where catalysts are prone to deactivation due to agglomeration and sintering of Pt particles. Herein, the Pt nanoparticles were effectively stabilized on AIPO‐18 molecular sieve by a biomolecule‐mediated green synthesis method. Based on the biocompatibility and electrostatic synergy of carboxymethyl chitosan (CMC), a high degree of Pt nanoclusters dispersion in AIPO‐18 zeolites was achieved. The hydroconversion of levulinic acid (LA)was carried out at 160°C and 2 MPa hydrogen pressure, and the LA conversion of Pt/AIPO‐18 (5CMC) reached 95.2% and the selectivity of γ‐valerolactone (GVL) was 97.9% after 2 h. Pt/AIPO‐18 (5CMC) exhibited satisfactory results that superior to the initial reactivity of Pt/AIPO‐18 (0CMC) after five runs.
Mesoscale hydrated morphology of perfluorosulfonic acid membranes
Authors: Wang Jihao , Chen Jia , Xu Zhiyang , Yang Xiaozhen , Ramakrishna Seeram , Liu Yong 
Published: February 2022

AbstractFuel cells are expected to play an important role in global carbon neutralization and future social development with high conversion efficiency and zero emissions. The core of the fuel cell is the proton exchange membrane (PEM). However, the unclear of the proton transport mechanism in PEMs limits the development of membranes with improved performance. Perfluorosulfonic acid (PFSA) membranes are currently the most widely used type of PEM, and exhibit varying proton transport capabilities with various chemical structures. In this study, the hydration morphology of several PFSA membranes was studied using dissipative particle dynamics. The result shows that under low water content the hydrophilic and hydrophobic phases separated and the water clusters are relatively isolated. The increased water content formed hydrophilic channels, while the increase in equivalent weight decreases the water cluster size and improves water dispersion. Aciplex 1128 shows great variation owing to the presence of a long sulfonic acid terminated side chain in water cluster size and dispersion compared with Nafion. The average diffusivity and mean square displacement results showed similar results. These results will promote the development of high performance PEM for fuel cells.
Vanadium removal from drinking water by fixed‐bed adsorption on granular ferric hydroxide
Authors: Bahr Carsten , Jekel Martin , Amy Gary 
Published: February 2022

AbstractThe metal vanadium (V), often present as pentavalent oxyanion vanadate, can be present in groundwaters worldwide due to natural origin. While there are presently no US drinking water standards for vanadium, the German Environmental Protection Agency has defined a guidance value of 4 μg/L in drinking water. Impacted water suppliers need an effective and selective treatment process for meeting this value. In 2020, an extended efficiency test (EET) was completed successfully at a water works in Daun, Germany using GEH®, Granular Ferric Hydroxide, an adsorbent that has been in use for over 20 years in several thousand treatment plants worldwide, primarily for removal of arsenic present as arsenate, with chemical similarities to vanadate. An EET, performed in a treatment plant with a flow of 34 m3/h over 13 months, demonstrated reliable removal of vanadium, present at 28 μg/L, down to the limit of quantification (2 μg/L). Thus, for water supplies with vanadium occurrence and a similar water quality, GEH® may provide an effective treatment option.