bluuebunny/crossref_metadata_2025_split huggingface dataset:
L1-norm based time-varying brain neural network and its application to dynamic analysis for motor imagery
Authors: Li Peiyang , Li Cunbo , Bore Joyce Chelangat , Si Yajing , Li Fali , Cao Zehong , Zhang Yangsong , Wang Gang , Zhang Zhijun , Yao Dezhong , Xu Peng 
Published: March 2022

Abstract

Objective
. Electroencephalogram (EEG)-based motor imagery (MI) brain-computer interface offers a promising way to improve the efficiency of motor rehabilitation and motor skill learning. In recent years, the power of dynamic network analysis for MI classification has been proved. In fact, its usability mainly depends on the accurate estimation of brain connection. However, traditional dynamic network estimation strategies such as adaptive directed transfer function (ADTF) are designed in the L2-norm. Usually, they estimate a series of pseudo connections caused by outliers, which results in biased features and further limits its online application. Thus, how to accurately infer dynamic causal relationship under outlier influence is urgent. Approach
. In this work, we proposed a novel ADTF, which solves the dynamic system in the L1-norm space (L1-ADTF), so as to restrict the outlier influence. To enhance its convergence, we designed an iteration strategy with the alternating direction method of multipliers, which could be used for the solution of the dynamic state-space model restricted in the L1-norm space. Furthermore, we compared L1-ADTF to traditional ADTF and its dual extension across both simulation and real EEG experiments. Main results
. A quantitative comparison between L1-ADTF and other ADTFs in simulation studies demonstrates that fewer bias errors and more desirable dynamic state transformation patterns can be captured by the L1-ADTF. Application to real MI EEG datasets seriously noised by ocular artifacts also reveals the efficiency of the proposed L1-ADTF approach to extract the time-varying brain neural network patterns, even when more complex noises are involved. Significance
. The L1-ADTF may not only be capable of tracking time-varying brain network state drifts robustly but may also be useful in solving a wide range of dynamic systems such as trajectory tracking problems and dynamic neural networks.
Serial powering and signal integrity characterization for the TEPX detector for the Phase-2 CMS Inner Tracker
Authors: Reimers A. C. 
Published: March 2022

Abstract
The entire CMS silicon pixel detector will be replaced to operate at the high-luminosity LHC. In this contribution, the new tracker endcap pixel detector will be presented, focusing on a novel concept to provide both power and data connectivity to the modules through a disk-shaped PCB. As this part of the detector also features the longest serial powering chains in the CMS Phase-2 Inner Tracker, emphasis is put on serial powering results and the characterization of the signal integrity.
Octopus-inspired sucker to absorb soft tissues: stiffness gradient and acetabular protuberance improve the adsorption effect
Authors: Wang Yi , Sun Guangkai , He Yanlin , Zhou Kangpeng , Zhu Lianqing 
Published: March 2022

Abstract
Rigid suckers commonly used in surgical procedures often cause absorption damage, while their soft counterparts are difficult to handle due to their weak anchoring. Alternatively, the octopus sucker is both soft and has strong suction power. Further observation revealed that its structure is self-sealing and that the tissues are layered in hardness. Inspired by said structure and the characteristics of associated materials, a bionic soft sucker with stiffness gradient and acetabular roof structure was proposed, made of silicone with varying hardness including structures such as acetabular roof and circle muscles. The automatic tensile force measurement system was used to experimentally analyze the adsorption performance of the suckers to the soft curved contact surface. Both dry and wet conditions were tested, along with practical tests on organisms. The bionic sucker adsorption force was increased by 25.1% and 34.6% on the cylindrical surface, and 45.2% and 7.3% on the spherical surface for dry and wet conditions, respectively. During the experiment, the bionic suckers did not cause notable suction damage to the contact surfaces. Thus, this type of bionic sucker shows good application prospects in the field of surgery.
Analytical solution and hidden symmetry operators of asymmetric two-mode quantum Rabi model
Authors: Yan Zhanyuan , Xia Yifei , Li Jurihui , Ma Jinying , Liu Yan 
Published: March 2022

Abstract
The asymmetric two-mode quantum Rabi model (tmQRM) breaks

Z

2

-symmetry and also implies hidden symmetry. In this paper, the energy spectrum are analytically computed with Bogoliubov transformation and SU(1, 1) Lie algebra. The analytical results are in good agreement with those obtained by numerical calculation. We identify the condition for the bias parameter such that level crossings appear in the spectrum which are caused by the hidden symmetry. This condition is related not only to the field frequency, but also to the coupling strength between the field and qubit. The level crossing points could be determined by the pole energy and recurrence coefficients. This is tested and verified in the low energy levels. The generators of the hidden

Z

2

-symmetry, commuting with the Hamiltonian, are derived within the Bogoliubov operator approach. The present results may provide more information to the hidden symmetry in the asymmetric tmQRM.
Hydration and pore structure characteristics of concrete incorporating internal curing materials in a dry and large-temperature-difference environment
Authors: Lu Yan , Wang Kun , Zhu Duo , Meng Qingxin , Cui Liyan 
Published: March 2022

Abstract
The climate in the Central Asian area is extreme dry, with a large temperature difference between day and night, and the concrete is easy to crack during the construction period under the conditions of traditional external curing. Therefore, this study concerns understanding the application of internal curing materials in a dry and large-temperature-difference environment. The effects of three internal curing materials, namely, Super Absorbent Polymer (SAP), Light Weight Aggregate (LWA) and Perforated Cenospheres (PCs), on hydration and pore structure characteristics of concrete were investigated. Scanning electron microscope (SEM) and x-ray diffractometer (XRD)were used to observe the microscopic morphology and physical phase composition of concrete, and the evolution of pore characteristics was analyzed using mercury intrusion porosimeter (MIP) to explore the mechanism of pore structure refinement. Results show that the pores formed by the release of water provide space for the accumulation of hydration products, thereby accelerating the formation of ettringite crystals. Results indicate that the continuous release of internal curing materials allows the interior of the concrete to continue to be hydrated, which greatly promotes the overall hydration of the cement. The effect of supplementary cementitious materials (GGBS, FA) and implications of large-temperature-difference environment on concrete durability are discussed.
3DG/Se4.7S3.3 composites with different morphologies as new all-solid-state lithium storage electrode materials
Authors: Shen Zhongli , Liu Fangchao , Hu Han , Fu Zhengwen 
Published: March 2022

Abstract
Selenium-sulfur(SexSy) composites can be used as energy storage materials for lithium batteries benefit from their integration of the high capacity of sulfur and the high conductivity of selenium. Herein, we prepared amorphous three dimensional reduced graphene oxide/selenium sulfide(a-3DG/Se4.7S3.3) composites and crystalline 3DG/Se4.7S3.3(c-3DG/Se4.7S3.3) composites by in situ synthesis and hydrothermal methods, respectively, in order to research the effect of different morphologies of 3DG/Se4.7S3.3 composites on the electrochemical properties of all-solid-state lithium batteries. Our study found that the a-3DG/Se4.7S3.3 cathodes displayed greater capacity and outstanding rate performance, with an initial discharge capacity of 926 mAh g−1 and utilization rate of 103% at 1/2C. And a first discharge capacity of up to 706 mAh g−1 at 7 C. Although the first discharge capacity of c-3DG/Se4.7S3.3 was 523 mAh g−1, its cycling stability was significantly improved compared with that of a-3DG/Se4.7S3.3 cathodes, and the Coulombic efficiency remained above 97% after 60 cycles at ½ C. In this work, we investigate the performance of solid-state batteries by preparing new SexSy composites with different morphologies and rational design of electrodes in terms of structure and morphology, which provides ideas for the preparation of electrodes in the future.
Effect of bimodal grain size and gradient structure on heterogeneous deformation induced (HDI) stress and mechanical properties of Cu
Authors: Yang Yi , Gong Yulan , Li Xingfu , Liu Huan , Li Cong , Yang Jingran , Pan Hongjiang , Shu Baipo , Deng Chao , Fang Junqi , Zhu Xinkun 
Published: March 2022

Abstract
In this study, two different types of heterogeneous structures were prepared by controlling different surface mechanical attrition treatment (SMAT) time (5 s, 10 s, 30 s, 60 s). The effect of heterogeneous Cu with bimodal grain size structure (BGSS) and gradient structure (GS) on heterogeneous deformation induced (HDI) stress and mechanical properties was investigated systematically. By combining surface morphology with microhardness distribution, it was found that the surface grains of the SMAT-ed Cu (5 s and 10 s) were partially refined to exhibit BGSS, while the surface grains of SMAT-ed Cu (30 s and 60 s) were sufficiently refined to form GS. The load-unload-reload (LUR) tests results showed that HDI stress for SMAT 60s Cu was much higher than that of the SMAT 10s Cu. Furthermore, microstructure characterizations revealed that SMAT-ed Cu with BGSS and GS suppressed strain localization, which resulted in high strength and reasonable ductility.
Machine learning-based method to adjust electron anomalous conductivity profile to experimentally measured operating parameters of Hall thruster
Authors: SHASHKOV Andrey , TYUSHEV Mikhail , LOVTSOV Alexander , TOMILIN Dmitry , KRAVCHENKO Dmitrii 
Published: March 2022

Abstract
The problem of determining the electron anomalous conductivity profile in a Hall thruster, when its operating parameters are known from the experiment, is considered. To solve the problem, we propose varying the parametrically set anomalous conductivity profile until the calculated operating parameters match the experimentally measured ones in the best way. The axial 1D3V hybrid model was used to calculate the operating parameters with parametrically set conductivity. Variation of the conductivity profile was performed using Bayesian optimization with a Gaussian process (machine learning method), which can resolve all local minima, even for noisy functions. The calculated solution corresponding to the measured operating parameters of a Hall thruster in the best way proved to be unique for the studied operating modes of KM-88. The local plasma parameters were calculated and compared to the measured ones for four different operating modes. The results show the qualitative agreement. An agreement between calculated and measured local parameters can be improved with a more accurate model of plasma-wall interaction.
Phase polynomials synthesis algorithms for NISQ architectures and beyond
Authors: Vandaele Vivien , Martiel Simon , Goubault de Brugière Timothée 
Published: March 2022

Abstract
We present a framework for the synthesis of phase polynomials that addresses both cases of full connectivity and partial connectivity for NISQ architectures. In most cases, our algorithms generate circuits with lower CNOT count and CNOT depth than the state of the art or have a significantly smaller running time for similar performances. We also provide methods that can be applied to our algorithms in order to trade an increase in the CNOT count for a decrease in execution time, thereby filling the gap between our algorithms and faster ones.
Qsun: an open-source platform towards practical quantum machine learning applications
Authors: Nguyen Quoc Chuong , Ho Le Bin , Nguyen Tran Lan , Nguyen Hung Q 
Published: March 2022

Abstract
Currently, quantum hardware is restrained by noises and qubit numbers. Thus, a quantum virtual machine (QVM) that simulates operations of a quantum computer on classical computers is a vital tool for developing and testing quantum algorithms before deploying them on real quantum computers. Various variational quantum algorithms (VQAs) have been proposed and tested on QVMs to surpass the limitations of quantum hardware. Our goal is to exploit further the VQAs towards practical applications of quantum machine learning (QML) using state-of-the-art quantum computers. In this paper, we first introduce a QVM named Qsun, whose operation is underlined by quantum state wavefunctions. The platform provides native tools supporting VQAs. Especially using the parameter-shift rule, we implement quantum differentiable programming essential for gradient-based optimization. We then report two tests representative of QML: quantum linear regression and quantum neural network.
Error estimates for a class of continuous Bonse-type inequalities
Authors: Marques Diego , Trojovský Pavel 
Published: March 2022

Let

p
n

p_n

be the

n
n

th prime number. In 2000, Papaitopol proved that the inequality

p
1

⋯

p
n

>

p

n
+
1

n
−
π
(
n
)

p_1\cdots p_n>p_{n+1}^{n-\pi (n)}

holds, for all

n
≥
2

n\geq 2

, where

π
(
x
)

\pi (x)

is the prime counting function. In 2021, Yang and Liao tried to sharpen this inequality by replacing

n
−
π
(
n
)

n-\pi (n)

by

n
−
π
(
n
)
+
π
(
n
)

/

π
(
log
⁡
n
)
−
2
π
(
π
(
n
)
)

n-\pi (n)+\pi (n)/\pi (\log n)-2\pi (\pi (n))

, however there is a small mistake in their argument. In this paper, we exploit properties of the logarithm error term in inequalities of the type

p
1

⋯

p
n

>

p

n
+
1

k
(
n
,
x
)

p_1\cdots p_n>p_{n+1}^{k(n,x)}

, where

k
(
n
,
x
)
=
n
−
π
(
n
)
+
π
(
n
)

/

π
(
log
⁡
n
)
−
x
π
(
π
(
n
)
)

k(n,x)=n-\pi (n)+\pi (n)/\pi (\log n)-x\pi (\pi (n))

. In particular, we improve Yang and Liao estimate, by showing that the previous inequality at

x
=
1.4

x=1.4

holds for all

n
≥
21

n\geq 21

.
The Adams spectral sequence for the image-of-𝐽 spectrum
Authors: Bruner Robert , Rognes John 
Published: March 2022

We show that if we factor the long exact sequence in cohomology of a cofiber sequence of spectra into short exact sequences, then the

d
2

d_2

-differential in the Adams spectral sequence of any one term is related in a precise way to Yoneda composition with the 2-extension given by the complementary terms in the long exact sequence. We use this to give a complete analysis of the Adams spectral sequence for the connective image-of-

J
J

spectrum, finishing a calculation that was begun by D. Davis [Bol. Soc. Mat. Mexicana (2) 20 (1975), pp. 6–11].
Circulating Cell-Free DNA and DNA Integrity as Molecular Diagnostic Tools in Hepatocellular Carcinoma
Authors: Elzehery Rasha , Effat Narmin , El Farahaty Reham , Elsayed Farag Raghda , Abo-Hashem Ekbal M , Elhelaly Rania 
Published: March 2022

Abstract

Objectives
We assessed the ability to use circulating cell-free DNA (cfDNA) and the DNA integrity index (DNAII) to detect the transition from liver cirrhosis (LC) to hepatocellular carcinoma (HCC).

Methods
Circulating cfDNA and DNAII were measured in 50 patients with advanced LC and 50 patients with HCC who were followed for 1 month after transarterial chemoembolization (TACE). Fifty healthy participants served as a control group. Real-time quantitative polymerase chain reaction (PCR) was used to measure circulating cfDNA concentration, and Alu-PCR was used to measure the concentration of Alu repeats, both short fragments (115 base pairs [bp]) and long fragments (247 bp). We compared liquid biopsy results with the relevant traditional markers.

Results
The HCC group showed significantly higher circulating cfDNA concentrations and DNAII values compared with the LC and control groups. No significant differences were found in circulating cfDNA concentrations and DNAII values between the LC and control groups. Circulating cfDNA concentrations decreased significantly after treatment (TACE); areas under the curve of circulating cfDNA concentration and DNAII values were significantly better than those of ɑ-fetoprotein and vascular endothelial growth factor in discriminating between LC and HCC.

Conclusions
The combined use of DNAII with proteins induced by vitamin K absence or antagonist showed better diagnostic performance in HCC. Circulating cfDNA could have a potential role in monitoring HCC treatment.
An updated vancomycin dosing protocol for initiating therapy in patients undergoing intermittent high-flux hemodialysis
Authors: Zelenitsky Sheryl A , Ariano Robert E 
Published: March 2022

Abstract

Purpose
To design an updated vancomycin dosing protocol for initiating therapy in patients undergoing chronic intermittent high-flux hemodialysis (iHFHD) that is congruent with the revised 2020 consensus guidelines for therapeutic drug monitoring (TDM).

Methods
Monte Carlo simulation methods were used to study vancomycin dosing for patients on iHFHD. Vancomycin regimens were constructed as intravenous infusions (for intradialytic administration) of a loading dose and maintenance doses 3 times weekly during subsequent dialysis sessions. Vancomycin plasma concentrations were simulated, and the probability of target attainment (PTA) for a 24-hour area under the time-concentration curve (AUC24) of 400 to 700 mg · h/L was determined. Standardized weight-based (ie, dose-banding) regimens were investigated, and an optimized protocol was selected based on TDM target attainment and practical considerations for use in the dialysis setting.

Results
The proposed vancomycin dosing protocol (for intradialytic administration) specifies 3 regimens: (1) a 1,500-mg loading dose and 750-mg maintenance doses for patients weighing 50 kg to 69 kg; (2) a 2,000-mg loading dose and 1,000-mg maintenance doses for patients weighing 70 kg to 89 kg; and (3) a 2,500-mg loading dose and 1,250-mg maintenance doses for patients weighing 90 kg to 110 kg. In a simulated hemodialysis population (n = 5,000), the proposed protocol delivered median (interquartile range [IQR]) loading and maintenance doses of 25.0 (23.4-26.6) mg/kg and 12.5 (11.8-13.3) mg/kg, respectively. The PTA for an AUC24 of 400 to 700 mg · h/L was 74.7% on day 1 and 70.8% on day 8, with less than 10% of values exceeding the target range.

Conclusion
Our proposed dosing protocol for patients undergoing iHFHD offers an updated and practical approach for initiating vancomycin therapy that can be optimized with early TDM.
Effectiveness of telepharmacy diabetes services: A systematic review and meta-analysis
Authors: Cao Diana X , Tran Rebecca J C , Yamzon Joycelyn , Stewart Tania L , Hernandez Elvin A 
Published: March 2022

Abstract

Purpose
Although pharmacist-provided diabetes services have been shown to be effective, the effectiveness of telepharmacy (TP) in diabetes management has not been clearly established. This systematic review and meta-analysis aims to evaluate the effectiveness of diabetes TP services.

Methods
PubMed, Embase, and the Cochrane Central Register of Controlled Trials (CENTRAL) were searched (from inception through September 2021) to identify published studies that evaluated the effect of TP services in patients with diabetes mellitus and reported either glycosylated hemoglobin (HbA1c) or fasting blood glucose (FBG) outcomes. Mean difference (MD), weighted mean difference (WMD), relative risk (RR), and 95% confidence intervals were calculated using the DerSimonian and Laird random-effects model.

Results
36 studies involving 13,773 patients were included in the systematic review, and 23 studies were included in the meta-analysis. TP was associated with a statistically significant decrease in HbA1c (MD, –1.26%; 95% CI, –1.69 to –0.84) from baseline. FBG was not significantly affected (MD, –25.32 mg/dL; 95% CI, –57.62 to 6.98). Compared to non-TP service, TP was associated with a lower risk of hypoglycemia (RR, 0.48; 95% CI, 0.30-0.76). In a subset of studies that compared TP to face-to-face (FTF) pharmacy services, no significant difference in HbA1c lowering was seen between the 2 groups (WMD, –0.09%; 95% CI, –1.07 to 0.90).

Conclusion
Use of TP was associated with reduction of HbA1c and the risk of hypoglycemia in patients with diabetes mellitus. High-quality randomized controlled trials are needed to validate the effectiveness of diabetes TP services relative to FTF services.
Development of a system-wide pharmacy operational weighted workload model at a large academic health system
Authors: Petersen Autumn E , Zeeman Jacqueline M , Vest Mary-Haston , Schenkat Daniel H , Colmenares Evan W 
Published: March 2022

AbstractPurposeThe purpose of this study is to develop a standard operational and distributional weighted workload model that is applicable across an integrated, diverse healthcare system. This model aims to not only demonstrate the operational intensity of pharmacy practice but also to inform opportunities to decrease waste, increase efficiency, facilitate growth, and demonstrate value across operational and distributional pharmacy services.SummaryTime studies were conducted at 8 hospitals within the UNC Health system to objectively measure time spent within each operational process in order to create a system-wide weighted workload model. Time study results informed the development of a system-wide weighted workload model. Data from December 29, 2019, through December 26, 2020, was then applied to this weighted workload model. With this model, acute care hospital and infusion center operational areas were compared in thousands of combinations within single operational areas and across any and all operational areas by dispense code, weighted work, and ratio of weighted work to total sum of dispenses at each site.ConclusionThe model successfully achieved the objective to develop a standard operational weighted workload model that is applicable across the integrated, diverse care system. This model provides a foundation for UNC Health to further productivity measurement and fills a gap in the literature by offering a novel method of developing a system-level operational workload model that can be used to evaluate and compare operational workloads across health-system sites.