bluuebunny/crossref_metadata_2025_split huggingface dataset:
3D CT Volumetry of Varient Gastric Reservoir after Sleeve Gastrectomy and Its Relation to Clinical Outcome
Authors: Hammad Dina Mostafa , Khadra Rania Sobhey Abo , Younes Rasha Lotfy , Sherif Mohamad Fouad 
Published: May 2022

Background: The role of radiology in gastric bariatric surgery is no longer limited for detection of postoperative complications, but also it extends to evaluate the role of surgical reduction of gastric size in body weight changes after surgery. The aim of this work was to assess the ability of 3D CT volumetry of variant gastric reservoir after sleeve gastrectomy and its relation to clinical outcome.
Methods: This prospective study that was carried out on 30 obese patients who was candidates for gastric sleeve surgery for the first time. All patients were subjected to clinical examinations [blood pressure, pulse rate and respiratory rate], pre-operative preparation: Blood testing, liver function, electrolytes and hormonal tests, an upper gastrointestinal (GI) endoscopy, abdominal ultrasound (US), echocardiography and CT volumetry
Results: There was no statistically significant correlation between body weight and gastric volume preoperative but a significant relation postoperative. Body weight, Body mass index (BMI) and gastric volume were significantly lower post-operative compared to pre-operative (P<0.001).
Conclusions: Computed tomography scan plays a significant role being a comprehensive imaging tool sensitive for accurate diagnosis of any suspected complication. Also, 3D CT volumetry adds more value in the evaluation of the new gastric pouch volume. In the setting of bariatric sleeve gastric surgery, MSCT volumetric assessment of the stomach is the gold standard imaging tool for evaluating gastric size in the postoperative phases.
Cerebroplacental Doppler Ratio and Cerebrouterine Doppler Ratio in Predicting Neonatal Outcome in Preeclamptic Pregnant Women
Authors: Elsharkawy Reem Taha , Khyat Ahmed Mahmoud El , Dakhakhni Raghda Ahmed El , Omar Mona Khaled , Hamoda Mahmoud Salah El Deen 
Published: May 2022

Background: Umbilical artery and middle cerebral artery Doppler ultrasound clearly depict the information about placental resistance and the changes in the fetal hemodynamics in response to it. The aim of this work was to assess the role of cerebroplacental ratio and cerebrouterine ratio in prediction of neonatal outcome in preeclamptic women.
Methods: This prospective observational study was carried out on 110 pre eclamptic women. Patients were divided into two groups: Preeclampsia with severe (n=58) and preeclampsia (n=52). All patients were subjected to laboratory testing (complete blood count (CBC), coagulation profile, liver and kidney function tests, 24 hours urine sample collection) and ultrasonographic scanning trans - abdominal sonographic examinations.
Results: The cut off value of CP ratio was 1.09 with sensitivity 84%, specificity 89%, PPV (positive predictive value) 94%, NPV (negative predictive value) 73% and accuracy 85% while the study cut off value of CU ratio was 1.3 with sensitivity 97%, specificity 93%, PPV 95%, NPV 95% and accuracy 95%. UTA, UMBA, MCA, CP and CU were significantly higher in Preeclampsia with severe than Preeclampsia (P value <0.05).
Conclusions: Most of unfavourable neonatal outcome associated with abnormal cerebroplacental and cerebrouterine ratio so cerebroplacental and cerebrouterine ratio were complementary to each other in predicting the adverse neonatal outcomes.
Efficacy of and Safety of Secukinumab in Psoriasis Vulgaris: A Prospective Study
Authors: Tirmizi Syeda Shahmoona , Iqbal Tayyaba , Ather Saher , Farooq Nadia , Mansoor Maria , Asar Marium , Kapadia Naseema , Ain Qurrat Ul 
Published: May 2022

Objective: Psoriasis is an immune mediated inflammatory skin disorder that potentially requires lifelong management. Different therapies treating psoriasis have been recognized wherein Secukinumab is a fully humanized, IL-17A monoclonal antibody that has been approved by US Food and Drug administration for the treatment of moderate to severe plaque psoriasis. Therefore, this study targeted to assess the efficacy of Secukinumab in patients with moderate to severe psoriasis.
Methodology: This was a Prospective interventional multicenter study conducted by using consecutive sampling technique. The duration of study was about one year. The sample size was 138. Adult patients between 18-65 years of either gender with clinical diagnosis of psoriasis vulgaris involving scalp, face, hands, or genital areas, were include. Treatment initiated by the administration of a single dose of 300 mg Secukinumab subcutaneously for 4 weeks then monthly for 52 weeks. Paired t-test was applied to assess the difference in the PASI score at various follow ups.
Results: The study results showed that out of 138 patients, 112(81.2%) were males and 26(18.8%) were females and their mean age was 40.47±9.55 years. As far as distribution of disease is concerned, 117(84.8%) patients reported Plaque Psoriasis, 57(41.3%) patients reported Scalp Psoriasis, 9(6.5%) patients reported nail Psoriasis, 11(8.0%) patients reported Palmoplantar Psoriasis, and 5(3.6%) patients reported Erythrodermic psoriasis. For the comparison of Secukinumab treatment under PASI scores, there was statistically significant reduction observed from mean of baseline PASI scores till 1 week (p<0.001), till 2 week (p<0.001), till 4 week (p<0.001), till 8 week (p<0.001). The improvement in mean PASI score from baseline to 1 year was 91%.
Conclusion: This study concluded that Secukinumab is a highly effective, rapid-acting biological therapy with no obvious adverse effects. Additionally, it was seen that secukinumab significantly reduced the baseline PASI score till 8 week rapidly in moderate and severe psoriasis.
Association of Postoperative Complications with Anemic Women Underwent Gynecologic and Obstetric Surgeries
Authors: Khan Farah , Jamshed Saira , Devi Ramna , Waleem Naureen , Hussain Razia , Khalid Sarwat , Siddiqui Ahsan Ali 
Published: May 2022

Objective: Preoperative anemia among women has been recognized as a risk factor for adverse postoperative complications following gynecologic and obstetric surgeries. Therefore, this retrospective analysis was conducted to assess the association of postoperative complications and comorbidities with anemia in women underwent gynecologic and obstetric surgeries.
Methodology: A retrospective study was carried out in the Department of Obstetrics and Gynecology of Hamdard hospital, Karachi by using non-probability, purposive sampling technique. A total of 200 women were chosen for this study wherein 89 women were anemic and 111 were non-anemic. Duration of the study was one year from July 2018 – June 2019. Adult female patients of 18 to 65 years having elective or emergency surgical procedure were included. Chi square test was applied to evaluate the association between religion, socioeconomic status, comorbidities, and postoperative complications with anaemia.
Results: The study results showed that the mean age of studied women was found 32.04±7.79 years and mean hospital stay was reported 3.38±1.08 days. Regarding Comorbidities, 89(100.0%) non diabetic were anemic while 6(5.4%) diabetic and 105(94.6%) non-diabetic were non-anemic with a significant association of diabetes with anemia (p=0.026). Regarding postoperative complications, significant association of fever was found with anemia (p<0.001). Moreover, 71(79.8%) anemic and 39(35.1%) non-anemic reported postoperative nausea and vomiting with a significant association between them (p<0.001). As far as wound infection is concerned, significant association of wound infection was observed with anemia (p=0.020).
Conclusion: This study concluded that postoperative fever, nausea and vomiting were observed significantly higher in anemic women than non-anemic underwent gynecologic and obstetric surgeries. Wound infection was also significantly associated with anemia. Therefore, educational and nutritional policies should be planned to persuade women to use iron-rich diet in order to decrease the burden on patients facing these complications.
Extraperitoneal pelvic lymphadenectomy to complement vaginal operations for cervical and endometrial cancer
Authors: Massi G , Susini T , Amunni G 
Published: July 2002

AbstractObjective: The aim of the current study was to test the applicability of a personal modification of Mitra extraperitoneal pelvic lymphadenectomy in combination with radical vaginal operations for treatment of endometrial and cervical cancer. Method: In a prospective series, 82 patients were submitted to extraperitoneal pelvic lymphadenectomy. In 34 cases of stage I endometrial cancer the procedure was combined with a class I vaginal hysterectomy and in 48 cases of cervical cancer stage Ib‐IIIb lymphadenectomy was associated with a class II or III radical vaginal hysterectomy. Type of anesthesia, number of lymph nodes removed, operating time, blood loss and postoperative complications were recorded. Result: The operation was performed with spinal anesthesia in 43% of the cases. Thirty‐seven patients (45%) were high surgical risk because of associated diseases. The median operative time for lymphadenectomy was 20 min for each side; the vaginal procedures took a median of 25 min (class I) and 40 min (class II‐III). Blood transfusions were necessary in seven cases (8.5%). A median of 26 lymph nodes were removed from each patient. Lymphocyst occurred in seven patients (8.5%), retroperitoneal hematoma in two and retroperitoneal abscess in one. Conclusion: Extraperitoneal pelvic lymphadenectomy has proven to be a safe and quick technique to complement vaginal operations for endometrial and cervical cancer. Specific features of this approach are: (1) fast, timesaving procedure; (2) possible use of spinal anesthesia; and (3) applicability in high surgical risk patients.
Kinetic description of the sideband instability in a helical-wiggler free-electron laser
Authors: Davidson Ronald C. 
Published: July 2002

The Vlasov–Maxwell equations are used to investigate properties of the sideband instability for a tenuous, relativistic electron beam propagating in the z direction through a constant-amplitude helical-wiggler magnetic field Bw(x)=B̂w(cos k0 zêx+sin k0 zêy). The theoretical model neglects longitudinal perturbations (δφ≂0) and transverse spatial variations (∂/∂x=0 =∂/∂y). Moreover, the analysis is carried out for perturbations about an equilibrium BGK state in which the distribution of beam electrons Gs(γ′) and the wiggler magnetic field (normalized amplitude aw=eB̂w/mc2k0) coexist in quasisteady equilibrium with a finite-amplitude, circularly polarized, primary electromagnetic wave (ωs,ks) with normalized amplitude as=eB̂s/mc2ks. Transforming the linearized Vlasov–Maxwell equations to the ponderomotive frame moving with velocity vp=ωs/(ks+k0), a formal dispersion relation is derived in the diagonal approximation, and the trapped- and untrapped-electron susceptibilities are calculated in terms of the exact electron trajectories in the ponderomotive frame, including the full influence of the finite-amplitude primary electromagnetic wave (ωs,ks).
Detailed properties of the sideband instability are investigated for the fundamental (n=1) mode in circumstances where ω′2≊ω̂2B(γ′) and the distribution of trapped electrons GTs(γ′) is localized near the bottom of the ponderomotive potential. Here ω′ and k′ denote the frequency and wavenumber in the ponderomotive frame, ω̂B(γ′) =(awasc2k′2p/γ′2)1/2 is the bounce frequency near the bottom of the potential, and kp=(ks+k0)/γp, where γp=(1−v2p/c2)−1/2. The growth rate and oscillation frequency of the sideband instability are calculated for several choices of trapped-electron distribution function GTs(γ′), ranging from a uniform distribution, to a monoenergetic distribution, to a monotonic decreasing distribution. A striking feature of the stability analysis is that the detailed stability properties are relatively insensitive to the form of GTs(γ′), at least in circumstances where the trapped electrons are localized near the bottom of the ponderomotive potential.
Industrialization, class structure, and social mobility in postwar Japan 1
Authors: Ishida Hiroshi 
Published: July 2002

ABSTRACTThis study examines intergenerational class mobility in Japan using cross‐national comparisons with Western nations and cross‐temporal comparisons of five national surveys conducted in postwar Japan. Cross‐national comparisons highlight the similarity in relative mobility pattern between Japan and Western nations and at the same time the Japanese distinctiveness in absolute mobility rates especially regarding the demographic character of the Japanese manual working class. The results of cross‐temporal comparisons of mobility pattern report some systematic trends in total mobility, inflow and outflow rates, reflecting the Japanese experience of late but rapid industrialization. The pattern of association between class origin and class destination, however, was stable in postwar Japan. It is therefore the combination of distinctive absolute mobility rates and similar relative mobility rates that characterizes the Japanese mobility pattern in comparison with the Western experience. Furthermore, Japan's distinctive pattern of postwar social mobility is characterized by a combination of rapidly changing absolute mobility rates and comparatively stable relative mobility rates.
Report on IUPsyS — UN activities
Authors: Sabourin Michel 
Published: July 2002

One of the most important conferences ever to be organized by the United Nations, the World Conference against Racism, Racial Discrimination, Xenophobia and Related Intolerance, will be held in South Africa, from August 31 to September 7, 2001. The UN Commission on Human Rights is acting as the Preparatory Committee for this World Conference. The purpose of the preparatory process is to raise public awareness of racism and racial discrimination globally and to focus on the action needed to fight it. Prior to the Conference, two preparatory meetings are planned. The first was held from 1 to 5 May 2000 in Geneva and the second will be in May/June 2001, also in Geneva. At the first Preparatory Committee meeting, a number of organizational decisions were taken, including adoption of the provisional agenda for the Conference and its draft rules of procedure. A voluntary fund has been established to provide additional resources for the preparatory process and the World Conference itself.In the next paragraphs, information concerning the background of this important conference is provided by the Department of Public Information of the UN to help a better comprehension of the issues. No doubt that the IUPsyS will have to find ways it can become more deeply involved in the process and participate actively in the actual deliberations that will take place in South Africa, next August, with the goal of eventually submitting recommendations.
Liver transplantation for alcoholic liver disease
Authors: Pageaux Georges‐Philippe , Perney Pascal , Larrey Dominique 
Published: July 2002

AbstractAlthough increasing numbers of alcoholic patients are being referred to liver transplant centres, liver transplantation for alcoholic liver disease still remains controversial, essentially because we are in an era of organ shortage. In fact, the main issue is the likelihood of relapse and its influence on outcome, because it is the possibility of returning to alcohol use that separates patients with alcoholic liver disease from those with other forms of chronic liver disease. In all proposed clinical guidelines of indications for referral and assessment for liver transplantation for alcoholic liver disease, the authors emphasize the risk of alcoholism recurrence and, thus, a multidisciplinary approach is required to select patients who are likely to comply with follow‐up and not return to a damaging pattern of alcohol consumption after transplantation. It emerges from all clinical studies that when we take into account the usual criteria of success for liver transplantation, i.e. patient and graft survival, rejection rate and infection rate, alcoholic liver disease is a good indication for liver transplantation. Predictive factors for alcoholic relapse after liver transplantation have been assessed in numerous studies, often with contradictory results making these difficult to analyse and compare. Several predictive factors for alcoholic relapse have been studied: length of abstinence before transplantation, associated psychiatric problems, social conditions, associated drug addiction, age. Abstinence after transplantation is the goal, but the necessary treatment for alcoholic disease can result in considerable improvement, even when complete abstinence is not achieved. Finally, the good results obtained with liver transplantation for alcoholic liver disease should help us to educate the general population about alcoholic disease.
A putative sigma1 receptor antagonist NE‐100 attenuates the discriminative stimulus effects of ketamine in rats
Authors: Narita Minoru , Yoshizawa Kazumi , Aoki Kazue , Takagi Misa , Miyatake Mayumi , Suzuki Tsutomu 
Published: July 2002

AbstractKetamine, one of the dissociative anaesthetic agents, has been shown to produce psychotomimetic effects. It has been well documented that activation of sigma receptors is responsible for the pathogenesis of some psychiatric disorders. In the present study, the effects of NE‐100, a putative sigma 1 receptor antagonist, was investigated in rats trained to discriminate between ketamine (5 mg/kg, i.p.) from saline under a fixed‐ratio 10 food‐reinforced procedure. Here we report for the first time that NE‐100 (1 mg/kg) produced a shift to the right in the dose–response curve for ketamine's discriminative stimulus effects. These results suggest that the sigma 1 receptor is, at least in part, involved in the discriminative stimulus effects of ketamine.
The Early Reading Screening Instrument: a method for identifying kindergarteners at risk for learning to read
Authors: Lombardino Linda J. , Morris Darrell , Mercado Laurie , DeFillipo Frank , Sarisky Carol , Montgomery Ann 
Published: July 2002

AbstractThis study was designed to provide speech‐language pathologists and educators with a method for identifying children at risk for reading failure. The Early Reading Screening Instrument (ERSI) was given to 149 end‐of‐the‐year kindergarten children. Half of the sample was tested 1 year later with standardized reading measures. Total ERSI scores from the kindergarten children strongly correlated with reading skills in first grade. Reading comprehension in first grade was the skill most strongly predicted by the subjects' total ERSI scores. The word recognition and invented spelling subtests of the ERSI were the best variables to be selected as predictors of first grade word analysis, word identification, and passage comprehension skills. A split‐half reliability study of the ERSI showed that a shortened form could be used with the same degree of predictive validity. The ERSI or similar tools can be used to assess reading readiness in kindergarten children so that we can promptly begin an intervention to prevent or, at the very least, to diminish risk for reading failure. For screening reading readiness across different languages or cultures, the content of the four ERSI subtests can easily be modified.
Factorization of the tenth Fermat number
Authors: Brent Richard 
Published: July 2002

We describe the complete factorization of the tenth Fermat numberF10F_{10}by the elliptic curve method (ECM).F10F_{10}is a product of four prime factors with 8, 10, 40 and 252 decimal digits. The 40-digit factor was found after about 140 Mflop-years of computation. We also discuss the complete factorization of other Fermat numbers by ECM, and summarize the factorizations ofF5,…,F11F_5, \dots , F_{11}.
Double Bruhat cells and total positivity
Authors: Fomin Sergey , Zelevinsky Andrei 
Published: July 2002

We study the totally nonnegative varietyG≥0G_{\ge 0}in a semisimple algebraic groupGG. These varieties were introduced by G. Lusztig, and include as a special case the variety of unimodular matrices of a given order whose all minors are nonnegative. The geometric framework for our study is provided by intersectingG≥0G_{\ge 0}with double Bruhat cells (intersections of cells of the two Bruhat decompositions ofGGwith respect to opposite Borel subgroups).
In Vivo Regulation of Human Skeletal Muscle Gene Expression by Thyroid Hormone
Authors: Clément Karine , Viguerie Nathalie , Diehn Maximilian , Alizadeh Ash , Barbe Pierre , Thalamas Claire , Storey John D. , Brown Patrick O. , Barsh Greg S. , Langin Dominique 
Published: July 2002

Thyroid hormones are key regulators of metabolism that modulate transcription via nuclear receptors. Hyperthyroidism is associated with increased metabolic rate, protein breakdown, and weight loss. Although the molecular actions of thyroid hormones have been studied thoroughly, their pleiotropic effects are mediated by complex changes in expression of an unknown number of target genes. Here, we measured patterns of skeletal muscle gene expression in five healthy men treated for 14 days with 75 μg of triiodothyronine, using 24,000 cDNA element microarrays. To analyze the data, we used a new statistical method that identifies significant changes in expression and estimates the false discovery rate. The 381 up-regulated genes were involved in a wide range of cellular functions including transcriptional control, mRNA maturation, protein turnover, signal transduction, cellular trafficking, and energy metabolism. Only two genes were down-regulated. Most of the genes are novel targets of thyroid hormone. Cluster analysis of triiodothyronine-regulated gene expression among 19 different human tissues or cell lines revealed sets of coregulated genes that serve similar biologic functions. These results define molecular signatures that help to understand the physiology and pathophysiology of thyroid hormone action.[The list of transcripts corresponding to up-regulated and down-regulated genes is available as a web supplement athttp://www.genome.org.]