bluuebunny/crossref_metadata_2025_split huggingface dataset:
Information sharing on social media pages related to wildlife conservation in a South African national game reserve
Authors: Schellnack-Kelly Isabel Stella 
Published: July 2022

Purpose
Social media sites contribute significantly to nature conservation in, that they enlighten and educate those members of the public who would ordinarily not be in a position, or would not be fortunate enough to visit the park and experience the various aspects first-hand. The purpose of this paper is to showcase social media pages related to a national game reserve in South Africa. This game reserve is the largest in the country and has a wide variety of conserved fauna and flora.

Design/methodology/approach
The theoretical framework used is the SCOPE framework that streamlines strategy development, content choice, refinement of online engagement, choice of social media platform and evaluations of social media campaigns.

Findings
The findings relate to the content found on these social media pages, as well as how members of the public interact with each other and officials from the game reserve in sharing experiences related to this wilderness area.

Research limitations/implications
The research is related to the Kruger National Park in South Africa and is limited to three social media sites.

Originality/value
Through its social media presence, this South African game reserve is able to share experiences from what is effectively a living museum, as well as from its library and archives, with members of the public and allowing individual members to share their encounters with wildlife and their historical memories of this wilderness area.
Experiencing time elapse phenomenon in nostalgia: effect on consumption behavior in adulthood
Authors: Sotelo-Duarte Manuel , Rajagopal  
Published: July 2022

PurposeThis paper aims to understand how mental time traveling impacts consumption by triggering nostalgia. The effects of nostalgic behavior are explored further in regards of its impact on dears and nears.Design/methodology/approachThis study is based on qualitative information from in-depth interviews. In total, 30 parents with children form Chihuahua, Mexico, answer to a semi-structured interview. Participants presented nostalgic orientation.FindingsNostalgic individual move back and forward in time through memory retrieval. Retrieval's quality is related to social impact during memory creation and retrieval process. Nostalgia is not only a cognitive process, but it manifests on behaviors that affects people around the nostalgic individuals. In the context of parent–child relationship, sharing nostalgia is useful for creating new bond across participants.Research limitations/implicationsContributions toward theory of memory, nostalgia and social learning were made. Result suggests social implications on nostalgic behavior because social interaction is important for quality of memory retrieval. Behavioral implications are discussed in the context of parent–child relationship and the use of nostalgia to develop new and stronger bonds. Companies should develop strategies that privilege social moments around brands to increase memory retrieval quality and nostalgia.Practical implicationsCompanies should develop strategies that create social moments around brands to increase memory retrieval quality and nostalgia. Additionally, using social moments on communications could trigger nostalgia and detonates consumption behavior.Originality/valueThe research builds on previous studies about nostalgia. However, this research focusses on mental time travel along nostalgic memories that individuals perform every day to take decisions that affects them and their loved ones. The value of nostalgia on building relationships through consumption is analyzed. The results were obtained from the Mexican context that has not been explored before on nostalgia research.
Assessment and treatment of pectus deformities: a review of reverse engineering and 3D printing techniques
Authors: Mussi Elisa , Servi Michaela , Facchini Flavio , Furferi Rocco , Volpe Yary 
Published: July 2022

Purpose
Among thoracic malformations, pectus deformities have the highest incidence and can result in a wide range of severe and mild clinical manifestations. Recently, the treatment of pectus deformities is shifting from traditional approaches toward customized solutions. This occurs by leveraging innovative rapid prototyping tools that allow for the design and fabrication of patient-specific treatments and medical devices. This paper aims to provide a comprehensive view of the growing literature in this area to analyze the progress made in this direction.

Design/methodology/approach
The search was performed on major search engines through keywords inherent to reverse engineering (RE) and additive manufacturing (AM) technologies applied to pectus deformities and related treatments, selecting 54 papers. These were analyzed according to the addressed pathology, the hardware and software tools used and/or implemented and their integration within the clinical pathway.

Findings
First, the analysis led to analyze and divide the papers according to how RE and AM technologies are applied for surgical and non-surgical treatments, pathological assessment and preoperative simulation and planning. Second, all papers were considered within the typical rapid prototyping framework consisting of the three phases of three-dimensional (3D) scanning, 3D modelling and 3D printing.

Originality/value
To the best of the authors’ knowledge, to date, no survey has provided a comprehensive view of innovative and personalized treatment strategies for thoracic malformations; the present work fills this gap, allowing researchers in this field to have access to the most promising findings on the treatment and evaluation of pathology.
Driving Global Convergence in Green Financial Policies: China as Policy Pioneer and the EU as Standard Setter
Authors: Larsen Mathias Lund 
Published: July 2022

AbstractAlthough policies for green financial systems are proliferating across the globe, the dynamics shaping such policies remain inadequately understood. With China and the EU at the global forefront of green financial policies, this paper demonstrates how they each influence global policy norms through their distinct policy models. This contributes to the literature, first, by improving our understanding of the global green financial policy processes and, second, by challenging current expectations from the literature. Analysing three central policy areas (information disclosure, taxonomies, and central banking) from an institutional approach, the paper, first, finds that green financial policies are both proliferating and converging globally. Second, the paper finds that China pioneered policy types around 2015, creating an Overton Window. Subsequently, since 2018, the EU has been standardising policy contents within the policy types that China pioneered. The findings suggest that China acts as a policy pioneer through its top–down policy approach, whereas the EU acts as a standard setter through its bottom–up approach. Although this confirms the literature's expectation that the EU creates global standards, it challenges the expectation that China is both primarily a recipient of policy practice and too unique for other countries to learn from directly. In the broader context, the findings imply that the current global situation of competing political models may be an advantage as countries complement each other through both competition and collaboration. Efforts to align financial systems with sustainable development have moved from industry‐led initiatives to state‐led green financial policies, which are now proliferating and converging across the globe. China and the EU are the most influential actors in shaping how countries across the world use green financial policy because China acts as a policy pioneer based on its top–down policymaking model and the EU acts as a standard setter based on its bottom–up model. Although China and the EU have competing governance and policymaking models, their differences may have been an advantage to scaling up green financial policies as they complement each other through different roles. Awareness of their roles and different approaches should inform future China‐EU policy coordination because harmonisation of practice remains a barrier to mainstreaming green finance. Other countries can benefit from awareness of policy developments in the EU and China to support their own policy development in terms of future scope and contents.
ITCH facilitates proteasomal degradation of TXNIP in hypoxia‐ induced lung cancer cells
Authors: Sun Qian , Wang Bi‐Bo , Wei Wei , Huang Gui‐Chun , Liu Lei‐Lei , Chen Wei‐Wei , Wang Jing , Zhao Xiao‐Yue , Lu Lu , Fang Rong , Zhu Chun‐Yan , Chu Xiao‐Yuan 
Published: July 2022

AbstractBackgroundLung cancer (LC) is one of the most common cancers and a leading cause of cancer‐related deaths worldwide. In many pathological conditions, particularly in the tumor microenvironment, cells and tissues frequently exist in a hypoxic state.Here, we evaluated Itchy E3 ubiquitin protein ligase (ITCH) expression in LC cells following hypoxia treatment.MethodsLC cell lines were treated with hypoxic condition. Cell migration, invasion, inflammation, reactive oxygen species (ROS) production, and apoptosis of LC cells were determined by wound healing assay, Transwell invasive assay, ELISA, DCFH‐DA staining, and flow cytometry, respectively. qPCR and WB were used to determine the expression of ITCH and TXNIP. Co‐IP was performed to assess the interaction between ITCH and TXNIP.ResultsITCH expression was downregulated in LC cells under hypoxic conditions. Next, LC cells were subjected to hypoxic conditions and changes in cell viability and metastasis were determined. Hypoxic conditions resulted in increased migration and invasion abilities of LC cells. Intracellular reactive oxygen species (ROS) production, inflammation, and apoptosis were also promoted by hypoxia. We found that ITCH overexpression led to the proteasomal degradation of thioredoxin‐interacting protein (TXNIP), whereas the expression of the ITCH C830A mutant did not affect TXNIP levels in LC cells. The gain‐of‐function experiment demonstrated that migration, invasion, ROS generation, inflammation, and apoptosis of hypoxia‐conditioned LC cells were ameliorated by ITCH overexpression, whereas the ITCH C830A mutant did not cause any changes in these phenotypes. Furthermore, the contribution of TXNIP knockdown and ITCH overexpression to the hypoxia‐induced features in LC cells with ITCH C830A was found to be similar.ConclusionOur results suggest a novel mechanism underlying the changes in ITCH‐mediated malignant phenotypes of hypoxia‐conditioned LC cells via TXNIP.
A rare presentation of anaplastic large cell lymphoma as a cavitary pulmonary mass with hypercalcemia
Authors: Chen Hsu‐Yuan , Kuo Yu‐Chu , Cheng Wen‐Chien , Chen Wei‐Cheng 
Published: July 2022

AbstractCavitary lung lesions found on chest imaging may point to various diseases. These lesions may be caused by numerous etiologies, such as infection, inflammatory diseases, or malignancy. Thus, its etiology may be challenging to differentiate using imaging alone. Differential diagnoses are created using a combination of clinical symptoms, medical history, laboratory results, and physical examination. Primary pulmonary lymphoma and anaplastic large cell lymphoma (ALCL) are rare differentials. Here, we report a case of ALCL that initially presented with back pain, intermittent fever, hemoptysis, hypercalcemia, and bilateral multiple cavitary lung nodules. Because a cavitary pulmonary mass with sustained hypercalcemia is commonly seen in patients with squamous cell carcinomas or pulmonary tuberculosis, patients with ALCL may be misdiagnosed and undergo delayed treatment. This study highlights that ALCL should be considered in patients presenting with a cavitary pulmonary mass and hypercalcemia.
99mTc bone scintigraphy does not affect preoperative workup for patients with potentially resectable esophageal squamous cell carcinoma
Authors: Wei Xiu‐feng , Chen Xian‐kai , Lu Lu , Luo Peng , Xu Lei , Xie Hou‐nai , Yang Ya‐fan , Yu Yong‐kui , Li Hao‐miao , Liu Qi , Zhang Rui‐xiang , Qin Jian‐jun , Li Yin 
Published: July 2022

AbstractBackground99mTc bone scintigraphy (BS) is the mainstay and most widely used technique in evaluation of bone metastasis (BM) in China. This study aimed to investigate the value of 99mTc BS in preoperative workup for patients with potentially resectable (cT1−4aN0−3) esophageal squamous cell carcinoma (ESCC).MethodsThis prospective cross‐section clinical trial (ChiCTR1800020304) enrolled a total of 385 patients with ESCC diagnosed at thoracic surgery clinic from October 2018 to September 2020. All patients were diagnosed with stage cT1−4aN0−3 and were potential candidates for surgical resection. BS was performed preoperatively and the treatment strategy was changed after confirmation of BM. The primary endpoint was the rate of change of the treatment regimen because of BM, while the secondary endpoint was the rate of positive BS findings.ResultsOut of the 385 patients, only two (0.5%) changed their treatment regimen because of BM. The rate of positive BS findings was 1%, while two patients (0.5%) had false‐positive or false‐negative results. The BS diagnostic performance for BM was sensitivity 50%, specificity 99.5%, positive predictive value 50%, negative predictive value 99.5%, and accuracy 99.0%. There was no significant difference in BM in relation to age, sex, tumor location or clinical stage.ConclusionOur data demonstrated that 99mTc bone scintigraphy does not significantly affect the preoperative workup in patients with potentially resectable ESCC, especially in early clinical stage patients.
Adolescent substance use and high school noncompletion: exploring the nature of the relationship using a discordant twin design
Authors: Davis Christal N. , Gizer Ian R. , Lynskey Michael T. , Statham Dixie J. , Heath Andrew C. , Martin Nicholas G. , Slutske Wendy S. 
Published: July 2022

AbstractBackground and AimsPrevious studies have demonstrated associations between substance use and reduced educational attainment; however, many were unable to account for potential confounding factors like genetics and the rearing environment. In the few studies that controlled for these factors, the substances assessed were limited to alcohol, cannabis, and tobacco. To address these limitations, we examined the relationship between adolescent use of seven kinds of substances, the number of additional substances used, and high school noncompletion within a large sample of Australian twins.DesignA series of two‐level generalized mixed effects logistic regressions were conducted to examine associations between adolescent substance use and high school noncompletion.SettingAustralia.ParticipantsA total of 9579 adult Australian twins from two cohorts of the Australian Twin Registry.MeasurementsAssessments of high school completion, childhood major depression, conduct disorder symptoms, substance use initiation, demographics, and parental educational attainment using the Australian version of the Semi‐Structured Assessment for the Genetics of Alcoholism.FindingsThere were unique within‐twin‐pair effects of use of sedatives (odds ratio [OR] = 22.39 [95% confidence interval (CI) = 1.18–423.48]) and inhalants/solvents (OR = 10.46 [95% CI = 1.30–84.16]) on high school noncompletion. The number of substances used in adolescence was strongly associated with high school noncompletion across all discordant twin models (ORs from 1.50–2.32, Ps < 0.03).ConclusionsIn Australia, adolescent substance use appears to be associated with early school dropout, with the effects of any given substance largely because of the confounding factors of parental education, childhood conduct disorder symptoms, and use of other substances. Sedatives and inhalants/solvents have effects on high school noncompletion that cannot be explained by polysubstance use or familial factors.
The association between buprenorphine treatment duration and mortality: a multi‐site cohort study of people who discontinued treatment
Authors: Glanz Jason M. , Binswanger Ingrid A. , Clarke Christina L. , Nguyen Anh P. , Ford Morgan A. , Ray G. Thomas , Xu Stanley , Hechter Rulin C. , Yarborough Bobbi Jo H. , Roblin Douglas W. , Ahmedani Brian , Boscarino Joseph A. , Andrade Susan E. , Rosa Carmen L. , Campbell Cynthia I. 
Published: July 2022

AbstractBackground and aimsBuprenorphine is an effective medication for opioid use disorder that reduces mortality; however, many patients are not retained in buprenorphine treatment, and an optimal length of treatment after which patients can safely discontinue treatment has not been identified. This study measured the association between buprenorphine treatment duration and all‐cause mortality among patients who discontinued treatment. Secondary objectives were to measure the association between treatment duration and drug overdose and opioid‐related overdoses.DesignMulti‐site cohort study.SettingEight US health systems.ParticipantsPatients who initiated and discontinued buprenorphine treatment between 1 January 2012 and 31 December 2018 (n = 6550). Outcomes occurring after patients discontinued buprenorphine treatment were compared between patients who initiated and discontinued treatment after 8–30, 31–90, 91–180, 181–365 and > 365 days.MeasurementsCovariate data were obtained from electronic health records (EHRs). Mortality outcomes were derived from EHRs and state vital statistics. Non‐fatal opioid and drug overdoses were obtained from diagnostic codes. Four sites provided cause‐of‐death data to identify fatal drug and opioid‐related overdoses. Adjusted frailty regression was conducted on a propensity‐weighted cohort to assess associations between duration of the final treatment episode and outcomes.FindingsThe mortality rate after buprenorphine treatment was 1.82 per 100 person‐years (n = 191 deaths). In regression analyses with > 365 days as the reference group, treatment duration was not associated with all‐cause mortality and drug overdose (P > 0.05 for both). However, compared with > 365 days of treatment, 91–180 days of treatment was associated with increased opioid overdose risk (hazard ratio = 2.94, 95% confidence interval = 1.11–7.79).ConclusionsAmong patients who discontinue buprenorphine treatment, there appears to be no treatment duration period associated with a reduced risk for all‐cause mortality. Patients who discontinue buprenorphine treatment after 91–180 days appear to be at heightened risk for opioid overdose compared with patients who discontinue after > 365 days of treatment.
Temporal resource partitioning and stochastic colonization explain the co‐occurrence of gall‐inducing insects in the super‐host plant Copaifera langsdorffii Desf. (Fabaceae)
Authors: de Carvalho‐Sposito Stella Henrique , Urso‐Guimarães Maria Virginia , da Silva Fernando Rodrigues 
Published: July 2022

AbstractGall‐inducing insects exhibit elevated levels of oviposition and host specificity. An interesting pattern within the interaction between gall‐inducing insects and host plants is the fact that some species of plants, called super‐hosts, harbour several species of gall‐inducing insects. However, little is known about the mechanisms influencing the coexistence of gall‐inducing insects in super‐host plants. Here, we tested the mechanisms that allow the coexistence of multiple gall‐inducing insects associated with Copaifera langsdorffii Desf., a super‐host tropical tree. Specifically, we tested three non‐exclusive hypotheses: (i) Spatial niche partitioning: gall‐inducing species will inhabit distinct organs in the same plant; (ii) temporal niche partitioning: gall‐inducing insects occupy the host plant in different months, and (iii) local‐regional relationship: regional richness will be high, while local richness will be low, indicating high turnover (i.e. β‐diversity) of insects among individuals of the super‐host plant. We found no evidence that gall‐inducing insects are inhabiting distinct organs in the same host plant or that they are occurring in different vertical or horizontal strata. Furthermore, the incidence of other gall‐inducing insects has little effect on whether a given focal species is also found in the host plant. In contrast, gall‐inducing insects showed temporal resource partitioning with species occurring in two different periods. We also found a low α‐diversity with individuals of C. langisdorffii harbouring different gall species composition. Our results show that the temporal resource partitioning and the high β‐diversity among host plants are the main factors explaining the high number of gall‐inducing insects associated with C. langisdorffii.
Q Fever awareness and risk profiles among agricultural show attendees
Authors: Hobbs Megan J. , Ketheesan Natkunam , Eastwood Keith , Massey Peter , Ranmuthugala Geetha , Norton Robert , Quirk Frances H. 
Published: July 2022

AbstractObjectiveTo assess awareness and risk of Q fever among agricultural show attendees.SettingUniversity of New England's Farm of the Future Pavilion, 2019, Sydney Royal Agricultural Show.ParticipantsParticipants were ≥18 years, fluent in English, Australian residents, and gave their informed consent.Main Outcome MeasuresParticipants reported whether they had ever heard of Q fever and then completed the ‘Q Tool’ (www.qfevertool.com), which was used to assess participants' demographics and risk profiles. Cross‐tabulations and logistic regression analyses were used to examine the relationship between these factors.ResultsA total of 344 participants were recruited who, in general, lived in major NSW cities and were aged 40–59 years. 62% were aware of Q fever. Living in regional/remote areas and regular contact with livestock, farms, abattoirs and/or feedlots increased the likelihood of Q fever awareness. Direct or indirect contact with feral animals was not associated with Q fever awareness after controlling for the latter risk factors. 40% of participants had a high, 21% a medium, and 30% a low risk of exposure. Slightly less than 10% reported a likely existing immunity or vaccination against Q fever. Among those who were not immune, living in a regional or remote area and Q fever awareness were independently associated with increased likelihood of exposure.ConclusionsAwareness of Q fever was relatively high. Although 61% of participants had a moderate to high risk of exposure to Q fever, they had not been vaccinated. This highlights the need to explore barriers to vaccination including accessibility of providers and associated cost.