bluuebunny/crossref_metadata_2025_split huggingface dataset:
Insights into the Photodynamics of Fluorescence Emission and Singlet Oxygen Generation of Fluorogen Activating Protein‐Malachite Green Systems
Authors: Deng Ziqi , Li Lan , Jia Han , Li Nga‐Fong , He Jiaxing , Li Ming‐De , Phillips David Lee , Li Ying 
Published: December 2022

AbstractThe self‐assembled fluorogen activating protein (FAP)‐malachite green (MG) complex is a well‐established protein‐ligand system, which can realize binding‐caused fluorescence turn‐on of MG and singlet oxygen (1O2) generation by MG iodination. To clarify the mechanism of fluorescence activation and 1O2 generation, the photodynamics of different halogen‐substituted MG derivatives and their corresponding FAP‐MG complexes were studied by femtosecond transient absorption spectroscopy and theoretical computations. The results show that the rotation of MG is restricted by FAP binding, which prevents a rapid internal conversion to allow a longer lifetime for the excited MG to undergo fluorescence emission and intersystem crossing. Moreover, these FAP‐MG complexes exhibit notably varied fluorescence quantum yields (ΦFL) and 1O2 yields. The study on the decay pathways indicates that such an anti‐heavy atom effect predominately stems from the lifetimes of the excited‐state species. The photodynamic mechanism study here will lead to more advanced FAP‐MG systems with high spatiotemporal resolution.
Third‐order super‐twisting control of a double stator asynchronous generator integrated in a wind turbine system under single‐phase open fault
Authors: Guettab Abdelkader , Bounadja Elhadj , Boudjema Zinelaabidine , Taleb Rachid 
Published: December 2022

SummaryThis paper deals with the control approach enhancement of a wind power generation system (WPGS) based on a double stator asynchronous generator (DSAG) under single‐phase open fault (SPOF). This type of machine, which collects the qualities of the squirrel cage asynchronous machine and these of the multiphase machine, has attracted the attention of several researchers, especially in the field of the wind energy. Classical sliding mode control (SMC) has been widely developed for the design of control systems. However, the use of SMC has several inconveniences such as the high chattering effect, large transient state error, and less robustness, which limit its utilization in practical applications. In order to improve the performance of the DSAG‐based WPGS, a third‐order super‐twisting controller (TOSTC) with chattering‐free is proposed. Then, an SPOF test is performed to prove the ability of the DSAG to work under degraded circumstances and guarantees to provide appropriate electrical energy to the grid without notable effects. The proposed system and its control under such conditions are illustrated by numerical simulations. The obtained results demonstrate the superior performance of the proposed system.
Effect of joints on microwave fracturing of the Bukit Timah granite using an open‐ended antenna
Authors: Ma Zhongjun , Zheng Yanlong , He Lei , Li Jianchun 
Published: December 2022

AbstractMicrowave fracturing of rocks before mechanical breakage could improve the performance of mechanical excavators and reduce environmental impacts. Previous research focused on the microwave fracturing of intact rock blocks. By using an open‐ended antenna, this paper investigates the effect of pre‐existing joints on the microwave fracturing of the Singapore Bukit Timah granite blocks. The results show that the specimens are weakened in the manners of cracking, spalling, melting, or a combination of them. The crack number and the total crack length produced by microwave treatment of jointed rock blocks are slightly smaller than those in the intact rock blocks. The interaction between joints and microwave‐induced cracks can be summarized into the following four patterns: (1) microwave‐induced cracks become arrested so that the crack propagation is terminated; (2) microwave‐induced cracks penetrate the joints and continue to propagate; (3) microwave‐induced cracks become deflected along the joints; and (4) microwave‐induced cracks propagate forward following the joints. The smaller the approach angle between the microwave‐induced crack and the pre‐existing joint is, the more microwave‐induced cracks tend to be arrested at the joint. Increasing the approach angle between the microwave‐induced crack and the joint can increase the chance of microwave‐induced crack penetrating the joint. The results also show that the smaller the distance is between the microwave radiation point and the joint, the easier it is for microwave‐induced cracks to penetrate the joints; otherwise, the microwave‐induced crack is more likely to be arrested at the pre‐existing joint.
Predictors of family‐based treatment for adolescent eating disorders: Do family or diagnostic factors matter?
Authors: Datta Nandini , Hagan Kelsey , Bohon Cara , Stern May , Kim Bohye , Matheson Brittany E. , Gorrell Sasha , Le Grange Daniel , Lock James D. 
Published: December 2022

AbstractObjectiveMisconceptions around which patients will and will not benefit from family‐based treatment (FBT) for adolescent eating disorders (EDs) limit referrals and access to this treatment modality. The present study explored whether common demographic and clinical factors that may prevent referral to FBT predict treatment outcomes in adolescent anorexia nervosa (AN) and bulimia nervosa (BN).MethodThe following predictors of treatment outcomes were assessed: baseline family and diagnostic factors (socioeconomic status, comorbidity, illness duration, parent feelings of self‐efficacy, family status, prior treatment, sex and prior hospitalizations) in a combined sample of adolescents receiving FBT compared to those randomized to other treatment conditions, across six clinical trials in the United States and Canada (total n = 724, ages 12–18, 90% female across both diagnoses). AN and BN samples were examined separately.ResultsAny prior ED treatment emerged as the only predictor of outcome in AN and BN, such that having no prior treatment predicted better outcomes in FBT for AN, and in both FBT and other treatment modalities for BN. No other sociodemographic or clinical variables predicted outcomes for AN or BN in FBT or in other evidence‐based treatment modalities.ConclusionsThe findings of this exploratory analysis suggest that commonly assumed factors do not predict outcome in FBT. Specifically socioeconomic and demographic factors or clinical variability in families seeking treatment do not predict treatment outcomes in FBT, or other evidence‐based treatment modalities, with the exception of prior treatment. Providers should consider referring to FBT even when these factors are present.Public SignificanceThis manuscript reports that commonly assumed family, sociodemographic and diagnostic factors do not predict outcome in FBT or other evidence‐based treatment modalities, with the exception of prior treatment. This data may be helpful for providers when considering referrals to FBT in the context of variability in these variables.
Divergent Behavior in the Chemistry of Metal‐Bis(dithiolene) Complexes Appended with Peripheral Aliphatic Butyl Chains
Authors: Prignot Erwan , Zhang Chanjuan , Jeannin Olivier , Halime Zakaria , Gramage‐Doria Rafael , Camerel Franck 
Published: December 2022

AbstractMetal‐bis(dithiolene) complexes derived from Ni(II), Co(II), Pd(II), Pt(II) and Au(III), bearing butyl aliphatic chains have been synthesized, and fully characterized by a variety of spectroscopic techniques including NMR, UV‐vis, IR, HRMS, CV, and X‐ray diffraction studies. This comparative study made possible to establish that the Co(II) species appear to be dimeric in the solid state as well as in solution. On the other hand, the coordination complexes based on Ni(II), Pd(II), Pt(II) and Au(III), feature a monomeric structure in both solution and solid state. These metal‐bis(dithiolene) complexes are remarkably stable in solution and, in stark contrast to precedents in the literature, they retain their square planar geometry even in presence of pyridine derivatives reported for their apical binding on metal‐bis(dithiolene) complexes.
Continuous Flow Chemistry Synthesis of Spirocyclic Sultams and Isoquinolines through Rhodium‐Catalyzed C−H Activation.
Authors: Zheng Ting , Lin Meng‐Ling , Dong Lin 
Published: December 2022

AbstractIn recent years, continuous flow technology have been applied to C−H activation to improve reaction efficiency. Herein, various imines and alkynes have been smoothly applied to continuous flow system. A series of spirocyclic sultams and isoquinolines can be obtained in excellent yields through [3+2] or [4+2] annulation reactions under relatively mild conditions.
One‐Pot Synthesis of 4‐Thiocyanato‐1H‐pyrazoles through Electrochemical Multicomponent Thiocyanation under Metal‐ and Oxidant‐Free Conditions
Authors: Zhang Ying , Xu Sen , Zhu Yutao , Xu Qingyu , Gao Huanjie , Liang Zeyao , Yao Xiaoquan 
Published: December 2022

AbstractAn electrochemical oxidative three‐component tandem reaction of arylhydrazines, 1,3‐diketones and ammonium thiocyanate has been established to construct 4‐thiocyanato‐1H‐pyrazoles under metal‐, oxidant‐free and mild conditions in an undivided cell. Various 4‐thiocyanato‐1H‐pyrazole derivatives could be obtained with broad substrate scope, and excellent functional group tolerance from available raw materials in moderate to excellent yields. This thiocyanation protocol with practicability and scalability features economical and eco‐friendly.
Pyridine‐Boryl Radical Mediated Decarboxylative Homolytic Substitution of N‐hydroxyphthalimide Ester with Ar2X2 (X=S, Se)
Authors: Cao Jia , Gao Liuzhou , Wang Guoqiang , Li Shuhua 
Published: December 2022

AbstractHerein, we report a metal‐free approach to construct C−X (X=S, Se) bonds with the broadly available N‐hydroxyphthalimide esters and disulfides/diselenides (Ar2X2, X=S or Se) using bis(pinacolato)diboron as the reductant. Density functional theory calculations and control experiments reveal that such a C−X bond formation process is reductive decarboxylation mediated from pyridine‐boryl radical to yield alkyl or aryl radical. The resulting carbon radical then reacts with disulfides or diselenides via a bimolecular homolytic substitution (SH2) mechanism to afford the corresponding sulfides or selenides. This method displays a high functional group tolerance and broad substrate applicability.
Modulation of central pain mechanisms using high‐definition transcranial direct current stimulation: A double‐blind, sham‐controlled study
Authors: Kold Sebastian , Graven‐Nielsen Thomas 
Published: December 2022

AbstractBackgroundThe use of high‐definition transcranial direct current stimulation (HD‐tDCS) has shown analgesic effects in some chronic pain patients, but limited anti‐nociceptive effects in healthy asymptomatic subjects.MethodsThis double‐blinded sham‐controlled study assessed the effects of HD‐tDCS applied on three consecutive days on central pain mechanisms in healthy participants with (N = 40) and without (N = 40) prolonged experimental pain induced by intramuscular injection of nerve growth factor into the right hand on Day 1. Participants were randomly assigned to Sham‐tDCS (N = 20 with pain, N = 20 without) or Active‐tDCS (N = 20 with pain, N = 20 without) targeting simultaneously the primary motor cortex and dorsolateral prefrontal cortex for 20 min with 2 mA stimulation intensity. Central pain mechanisms were assessed by cuff algometry on the legs measuring pressure pain sensitivity, temporal summation of pain (TSP) and conditioned pain modulation (CPM), at baseline and after HD‐tDCS on Day 2 and Day 3. Based on subject's assessment of received HD‐tDCS (sham or active), they were effectively blinded.ResultsCompared with Sham‐tDCS, Active‐tDCS did not significantly reduce the average NGF‐induced pain intensity. Tonic pain‐induced temporal summation at Day 2 and Day 3 was significantly lower in the NGF‐pain group under Active‐tDCS compared to the pain group with Sham‐tDCS (p ≤ 0.05). No significant differences were found in the cuff pressure pain detection/tolerance thresholds or CPM effect across the 3 days of HD‐tDCS in any of the four groups.ConclusionHD‐tDCS reduced the facilitation of TSP caused by tonic pain suggesting that efficacy of HD‐tDCS might depend on the presence of sensitized central pain mechanisms.
State of the art of augmented reality capabilities for civil infrastructure applications
Authors: Xu Jiaqi , Doyle Derek , Moreu Fernando 
Published: December 2022

AbstractAugmented reality (AR) is a technology superimposes interactional virtual objects onto a real environment. Since the beginning of the millennium, AR technologies have rapidly grown, with significant research publications in engineering and science. However, the civil infrastructure community has minimally implemented AR technologies to date. Civil engineers face one of the challenges when understanding and using AR is the lack of a classification of AR in the context of capabilities for civil infrastructure applications. Like most engineering fields, practitioners in civil infrastructure prioritize understanding a new technology's maturity level before considering its adoption and field implementation. This article compares the capabilities of 16 AR head‐mounted devices (HMDs) available in the market since 2017, ranking them in terms of performance for civil infrastructure implementations. Finally, the authors recommend a development framework for functional AR interfaces with civil infrastructure and operations.
Rational engineering of metal–organic coordination networks into facet‐controlled phosphides for overall water splitting
Authors: Yilmaz Gamze , Yang Tong , Lim Kane Jian Hong , Chee See Wee , Shen Lei , Mirsaidov Utkur , Bosman Michel , Ho Ghim Wei 
Published: December 2022

AbstractAlthough transition metal phosphide electrocatalysts display unique electronic structure that serves as functional centers for hydrogen evolution reaction, the synthesis of this class of materials for oxygen evolution remains a challenge due to the complex multielectron transfer pathways and sluggish reaction kinetics. This study details an in‐situ modification and transformation of cyanide‐bridged nickel‐iron (CN‐NiFe) organometallic hybrid into the preferential Fe2P phase with prevailing exposed faceted active centers by leveraging on the facile coordinate cleavage dynamics and compound reactivity of labile metal organic coordination frameworks. The resultant transition metal phosphide attains high electrochemical surface area, low Tafel slope, and low overpotential for the oxygen evolution reaction, while also demonstrating bifunctional electrocatalytic performance for overall water splitting. Comprehensive experimental studies and density functional theory calculations reveal that the exceptional catalytic activity originates from the transformation of framework metallic sites into preferential active sites allows an optimal adsorption of oxygen evolution reaction intermediates.image
RETRACTED: Workflow task scheduling for homogeneous environments on multiprocessing based on IoT variant of beta artificial bee colony
Authors: Shukla Dhirendra Kumar , Singh Jagriti , Muthusamy Sakthivel , Satpathy Sambit , Goyal Vishal 
Published: December 2022

AbstractIn the present era of supercomputing, the efficient scheduling of tasks is the first priority of the IoT and cloud service provider. Their objective is to utilize the maximum resource in order to fulfill various clients' requests. The scheduling of task on multiple processors increases change of underutilization of resources. Hence, this demand‐efficient scheduling algorithm that fulfills computer service provider's demands. This paper proposes a modified artificial bee colony algorithm for scheduling of multiple tasks on multiple processors by introducing crossover operation in employee bee phase to reduce the slow convergence rate. This proposed approach is tested on various scenarios in which there exist condition dependency among the tasks exists. The experimental results reduced the proposed approach to reduce the overall makes pan on an average by 15.37%.
Extracellular vesicle long RNA markers of early‐stage lung adenocarcinoma
Authors: Zhang Yanwei , Liu Wei , Zhang Hongdao , Sun Beibei , Chen Tianxiang , Hu Minjuan , Zhou Haisheng , Cao Ying , Han Baohui , Wu Ligang 
Published: December 2022

AbstractLung cancer screening by low‐dose computed tomography (LDCT) can improve mortality rates among high‐risk individuals, especially adenocarcinoma cases with characteristically poor prognosis, although high false‐positive rates have limited its clinical application. The objective of our study was to identify biomarkers for early‐stage lung adenocarcinoma (ie, tumor diameter <2 cm) through extracellular vesicle long RNA (evlRNA) sequencing. High throughput evlRNA sequencing and support vector machine (SVM) identification of candidate diagnostic marker transcripts were performed using serum samples obtained before lung surgery. A total of 145 upregulated and 363 downregulated differential genes (P value <.05, fold change >1.5) were identified between lung adenocarcinoma (LUAD) patients and benign controls. An SVM model based on a 23‐gene signature could distinguish EV samples of LUAD patients from those of control subjects with 86.49% sensitivity, 95.00% specificity and 92.31% accuracy in the training set and 93.75% sensitivity, 85.71% specificity and 88.24% accuracy in the validation set. A 17‐gene signature was then identified that could distinguish AIS patient samples from those of MIA/IAD patients with 93.33% sensitivity, 98.00% specificity, and 96.25% accuracy in the trainingset and 83.33% sensitivity, 96.55% specificity, and 94.29% accuracy in the validation set. EvlRNAs in serum show considerable diagnostic value for screening LUAD patients with tumor sizes <2 cm in conjunction with LDCT, potentially reducing false positive rates while improving mortality rates.
Urinary exosomal prostate‐specific antigen is a noninvasive biomarker to detect prostate cancer: Not only old wine in new bottles
Authors: Wei Chunmeng , Chen Xi , Ji Jin , Xu Yalong , He Xing , Zhang Huiyong , Mo Zengnan , Wang Fubo 
Published: December 2022

AbstractThe study aimed at evaluating the performance of urinary exosomal prostate‐specific antigen (UE‐PSA) to predict the results of initial prostate biopsies and discriminate clinically significant prostate cancer (Gleason score ≥ 7, csPCa) from nonsignificant PCa (Gleason score < 7, nsPCa) plus benign patients. Two hundred seventy‐two consecutive participants were admitted who underwent a prostate biopsy. The UE‐PSA expression was detected by enzyme‐linked immunosorbent assay (ELISA). The predictive power and clinical value of UE‐PSA was assessed by receiver operating characteristic (ROC), decision curve analysis (DCA) and waterfall plots. UE‐PSA was upregulated in PCa compared to benign patients (P < .001) and csPCa compared to nsPCa plus benign patients (P < .001). UE‐PSA achieved an AUC of 0.953 (0.905‐0.989) in distinguishing PCa from benign patients and an AUC of 0.879 (0.808‐0.941) in predicting csPCa from nsPCa plus benign patients. These results were validated in an additional multicenter cohort. In addition, DCA showed that UE‐PSA achieved the highest net benefit at almost any threshold probability compared to tPSA and %fPSA. As the waterfall plot showed, the UE‐PSA assay could avoid 57.6% (155 cases) and 34.6% (93 cases) unnecessary biopsies while only missing 2.6% (7 cases) and 1.5% (4 cases) of the cases of csPCa at the cutoff value of 90% and 95% sensitivity, respectively. We validated that UE‐PSA presented great diagnostic power and clinical utility to diagnose PCa and csPCa. UE‐PSA could be a promising noninvasive biomarker to improve PCa detection.
Financial inclusion and economic growth: What roles do institutions and financial regulation play?
Authors: Ofoeda Isaac , Amoah Lordina , Anarfo Ebenezer Bugri , Abor Joshua Yindenaba 
Published: December 2022

AbstractThe extant literature indicates that financial inclusion has a direct influence on economic growth. This has been examined by previous studies by analysing the link between financial inclusion and economic growth. This study uses the two‐step system GMM approach to investigate the moderating role of financial regulation and quality of institutions on the linkage between economic growth and financial inclusion in Africa, using balanced panel data of 52 African countries spanning 2002–2019. The findings reveal a number of things; (i) financial inclusion, financial regulation, and all proxies of institutional quality exert strong and significant effects on economic growth; (ii) institutional quality enhances the impact of financial inclusion on economic growth; iii. Financial regulation dampens the effect of financial inclusion on economic growth. Based on these findings, we recommend the following; (i) central, local governments, and policymakers should formulate public policy that promotes inclusive finance. Such policies should aim at removing barriers and constraints such as excessive customer identification requirements that hinder people from gaining access to finance; (ii) central governments and policymakers in Africa should refine policy that promotes the involvement of the citizenry in governance processes, promote accountability of public institutions, ensure effective governance systems, controls corruption, promote rule of law, and political stability and ensure quality legal and regulatory regimes; (iii) African central governments should fine‐tune policy aimed at strengthening institutions and the regulatory framework. By implication, strong, independent, and quality institutions coupled with sound financial regulatory framework is required to spur the growth of African countries.
The mediating role of thinking styles in the relationship between adolescent time perspective and subjective well‐being
Authors: Kuan Tat‐Yeung James 
Published: December 2022

AbstractIntroductionThe mechanism behind how time perspective (TP) relates to subjective well‐being is not fully understood and thinking styles might be potential mediators. However, our understanding of the relationship between thinking styles and subjective well‐being is currently limited to adult studies. This study aims to extend the literature by examining the mediating role of thinking styles in the relationship between TP and subjective well‐being in an adolescent sample.MethodsOne hundred forty‐nine male and one hundred and fourteen female secondary school students (13–18 years old) in Hong Kong responded to the Thinking Styles Inventory‐Revised II (TSI‐R2), the Zimbardo Time Perspective Inventory (ZTPI), the Positive and Negative Affect Schedule (PANAS), and the Temporal Satisfaction with Life Scale (TSWLS) in two waves separated by 2 months in 2017.ResultsAfter controlling for gender and TP, internal and external styles positively predicted positive affect and future life satisfaction after 2 months. Adaptive Type I hierarchical style positively predicted both positive and negative affect after 2 months, which supports the two‐dimensional structure of affect. Unexpectedly, maladaptive Type II styles did not predict subjective well‐being. Longitudinal mediation using cross‐lagged panel model showed that thinking styles mediated three relationships between TP and subjective well‐being. The internal style mediated the relationship between Past‐Negative TP, positive affect, and future life satisfaction, while the external style mediated the relationship between Future TP and future life satisfaction.ConclusionsThinking styles predicted adolescent subjective well‐being and acted as mediators in the relationship between TPs and subjective well‐being.