bluuebunny/crossref_metadata_2025_split huggingface dataset:
High resistance of Blastocystis to chlorine and hydrogen peroxide
Authors: Martín-Escolano Rubén , Ng Geok Choo , Tan Kevin S. W. , Stensvold C. Rune , Gentekaki Eleni , Tsaousis Anastasios D. 
Published: August 2022

Abstract
Blastocystis is a ubiquitous, widely distributed protist inhabiting the gastrointestinal tract of humans and other animals. The organism is genetically diverse, and so far, at least 28 subtypes (STs) have been identified with ST1–ST9 being the most common in humans. The pathogenicity of Blastocystis is controversial. Several routes of transmission have been proposed including faecal-oral (e.g. zoonotic, anthroponotic) and waterborne. Research on the latter has gained traction in the last few years with the organism having been identified in various bodies of water, tap water and rainwater collection containers including water that has been previously filtered and/or chlorinated. Herein, we assessed the resistance of 11 strains maintained in culture, spanning ST1–ST9 to various chlorine and hydrogen peroxide concentrations for 24 hours and performed recovery assays along with re-exposure. Following treatment with both compounds, all subtypes showed increased resistance, and viability could be visualised at the cellular level. These results are hinting at the presence of mechanism of resistance to both chlorine and hydrogen peroxide.
Application of high-flow nasal cannula oxygenation in the induction of general anesthesia by direct providers: A case series
Authors: Liu Fanfan , Meng Fansi , Chen Haiming , Hu Sheng 
Published: August 2022

Abstract
Background: Pressurized mask-assisted ventilation is commonly used during general anesthesia, which often requires the cooperation of two anesthesiologists and creates a severe shortage of anesthesiologists. High-flow nasal cannula oxygenation (HFNCO) is reportedly effective in perioperative airway management, but its safety and efficacy in the induction of general anesthesia by direct providers have not been confirmed. Methods: Twelve patients were enrolled in our study. Their vital signs were recorded before surgery (T0), and HFNCO was continuously applied after admission. Blood gas analysis results were recorded before pre-oxygenation (T1), during anesthetic induction (T2), and before mechanical ventilation (T3). Results: The mean arterial partial pressure of oxygen (PaO2) was 86.6±26.0, 245.3±90.6, and 170.0±99.4 mmHg at T1, T2, and T3, respectively, and the lowest pulse oxygen saturation (SpO2) was 92% at T3. The mean arterial partial pressure of carbon dioxide (PaCO2) was 39.0±6.2, 40.0±5.7, and 50.2±8.7 mmHg, respectively; the highest was 71.1 mmHg. The mean pH was 7.40±0.02, 7.39±0.05, and 7.35±0.06, respectively. One patient switched to pressurized mask-assisted ventilation because of severe hypoxemia (lowest SpO2, 82%) during apnea oxygenation. Conclusions: HFNCO significantly improves oxygenation levels without severe hypercapnia and can be safely applied to general anesthesia induction by direct providers.
Preparation of humidity-responsive cinnamon essential oil nanomicelles and its effect on post-harvest quality of strawberries
Authors: Luo Yali , Su Jingyi , Guo Shuangfeng , Cao Zhaoxin , Liu Zhiming , Wu Shang , Mao Yueyang , Zheng Yan , Shen Wen , Li Tingting , Ge Xuemei 
Published: August 2022

Abstract
Biodegradable materials have attracted considerable attention to be applied in maintaining food quality and safety due to their ability of a sustained release of antimicrobial agents. In this study, cinnamon essential oil (CEO) loaded poly (ethylene glycol)-poly (ε-caprolactone) (PEG-PCL) micelles (CEO-micelles) were prepared for humidity-controlled CEO release and preservation of strawberry quality. The CEO-micelles with spherical shape and uniform size were obtained, and a high encapsulation rate (92.00 ± 1.77%) of CEO was achieved. X-ray diffraction demonstrated that the CEO was successfully encapsulated in PEG-PCL micelles. The release rate could be controlled by adjusting the relative humidity (RH) and 75% RH was favorable for CEO release from micelles (with 72% total amount release in 7 d). The encapsulation of CEO with high concentrations in PEG-PCL micelles reduced the cytotoxicity. Additionally, CEO-micelles exhibited high antifungal activity against Botrytis cinerea, the main pathogenic fungus of strawberry. Finally, the application of CEO-micelles to the preservation of strawberries had a positive effect on changes in decay rate, weight loss, firmness, color and total soluble solids.
Risk factors for refractory enterocutaneous fistula following button jejunostomy removal and its treatment using a novel extraperitoneal approach in patients with esophageal cancer: A retrospective cohort study
Authors: Kamada Teppei , Ohdaira Hironori , Nakashima Keigo , Nishide Ryo , Takahashi Junji , Ito Eisaku , Nakaseko Yuichi , Suzuki Norihiko , Yoshida Masashi , Eto Ken , Suzuki Yutaka 
Published: August 2022

Abstract
BackgroundEnterocutaneous fistula after removal of the jejunostomy tube leads to multiple problems, such as cosmetic problems, decreased quality of life, electrolyte imbalances, infectious complications, and increased medical costs. However, the risk factors for refractory enterocutaneous fistula (REF) after button jejunostomy removal remain unclear. Therefore, in this study, we assessed the risk factors for REF after button jejunostomy removal in patients with esophageal cancer and reported the surgical outcomes of the novel extraperitoneal approach (EPA) for REF closure.MethodsThis retrospective cohort study included 47 patients who underwent button jejunostomy removal after esophagectomy for esophageal cancer. We assessed the risk factors for REF in these patients and reported the surgical outcomes of the novel EPA for REF closure at the International University of Health and Welfare Hospital between March 2013 and October 2021. The primary endpoint was defined as the occurrence of REF after removal of the button jejunostomy, which was assessed using a maintained data base. The risk factors and outcomes of the EPA for REF closure were retrospectively analyzed.ResultsREFs occurred in 15 (31.9%) patients. In the univariate analysis, REF was significantly more common in patients with albumin level<4.0 g/dL (p=0.026), duration>12 months for button jejunostomy removal (p=0.003), and with a fistula<15.0 mm (p=0.002). The multivariate analysis revealed that a duration>12 months for button jejunostomy removal (odds ratio [OR]:7.15; 95% confidence interval [CI]: 1.38–36.8; p=0.019), and fistula<15.0 mm (OR: 8.08; 95% CI: 1.50–43.6; p=0.002) were independent risk factors for REF. EPA for REF closure was performed in 15 patients. The technical success rate of EPA was 88.2%. Of the 15 EPA procedures, fistula closure was achieved in 12 (80.0%). The complications of EPA (11.7%) were major leakages (n=3) and for two of them, EPA procedure was reperformed, and closure of the fistula was finally achieved. ConclusionThis study suggested that duration>12 months for button jejunostomy removal and fistula<15.0 mm are the independent risk factors for REF after button jejunostomy removal. EPA for REF closure is a novel, simple, and useful surgical option for patients with REF after esophagectomy.
Prediction Model for the Compressive Strength of Green Concrete using Cement Kiln Dust and Fly Ash
Authors: Bakhoum Emad S. , Amir Arsani , Osama Fady , Adel Mohamed 
Published: August 2022

Abstract
Integrating artificial intelligence in construction industry is a challenge that can help to move towards sustainable construction. Therefore, Artificial Neural Network (ANN), which is a computing system that simulates the human brain processes, can be helpful tool for prediction of the compressive strength of green concrete. Green concrete can be made using waste materials as a replacement portion of cement (supplementary cementitious materials) or aggregate that can benefit in the reduction of negative impacts on the environment and improve its compressive strength. This research aims to predict the compressive strength of green concrete that includes a ratio of cement kiln dust (CKD) and fly ash (FA), as industrial by-products, using artificial neural network technique and MATLAB software. The developed ANN model is based on the collected necessary information about the concrete components and compressive strengths from literature. Two models have been trained and tested. The first includes CKD in the concrete mix using 35 training samples with 3 hidden layers. While the second includes CKD and FA in the concrete mix using 42 training samples with 7 hidden layers. The results of both models showed a good prediction of the compressive strength of green concrete with error less than 10%. The benefits of this nondestructive approach may include preservation of natural resources, reduction of greenhouse gasses emissions, cost, time, and waste to landfill as well as saving energy.
Ultra-wide bandwidth all-solid specialty bandgap fiber for ultrashort pulse delivery
Authors: Biswas Piyali , Pal Bishnu Pada , Ghosh Somnath 
Published: August 2022

Abstract
Photonic bandgap (PBG) fibers provide a versatile platform for ultra-short pulse delivery with low-loss, and low dispersion. Precisely, Braggkind of 1D PBG fibers with periodic cladding bilayers offer ample degrees of freedom to tailor fiber bandwidth along with loss, and dispersion. In this paper, we propose a next-level specialty bandgap fiber with multiple concentric cores based on the 1D PBG geometry in an all-solid form. It has three sets of tailored bilayer thickness in which each set of bilayer forms an effective core region that allows confinement of specific range of wavelengths. Thus, the successive overlap of the wavelength ranges supported by each of these concentric cores effectively enhances the overall transmission bandwidth of the fiber. Moreover, the concept can be extended to form a large number of concentric cores that allows further enhancement of the fiber bandwidth. As a proof-of-concept, an ultra-wide low-loss bandwidth covering a wavelength range of ~ 1600 nm for the fundamental mode has been achieved. Going beyond, an advanced level customization of the proposed fiber geometry has enabled further minimization of loss and enhancement in structural robustness. The propagation dynamics of an ultrashort pulse ~ 300 fs have been investigated numerically in both the normal and the anomalous dispersion regime of the proposed specialty fiber in the presence of nonlinearity and loss. Eventually, such all-solid multicore large-bandwidth fiber is proposed as a promising candidate for the delivery of ultrashort optical pulses over long distance with minimum amount of distortion and wave-breaking possible.
A Construction of Involutory Recursive-Like MDS Matrices via Self-Reciprocal Generator Polynomials of Reed-Solomon Codes
Authors: Tran Thi Luong , Nguyen Ngoc Cuong , Dinh Thi Xinh 
Published: August 2022

Abstract
Using a recursive MDS matrix over a finite field in the diffusion layer of block ciphers is a standard method to maximize the diffusion while minimizing the implementation cost. On the other hand, an involutory MDS matrix (the matrix is the inverse of itself) simplifies the implementation of the cipher as the same module can be used for both encryption and decryption. However, it has been shown (Gupta et al.’21) that there doesn’t exist a recursive MDS matrix M that is also involutory over a field of charateristic 2 except for a trivial case. Another option is to use a recursive-like involutory MDS matrix of the form RM, where M is a recursive matrix and R is a permutation matrix. In fact, Gupta et al. proved that over a field of characteristic 2, if f is a monic, self-reciprocal polynomial of degree m, Cf is the companion matrix of f and M = Cfm is MDS, then RM is an involuntary MDS matrix, where R is the matrix reversing the order of rows in M. With RM in the diffusion layer, one can use the same LFSR for both encryption and decryption while still taking advantage of the fact that M is recursive. In this paper, we extend the work of Gupta et al. and establish a necessary and sufficient condition for the generator polynomials of Reed-Solomon codes over a finite field of arbitrary characteristic to be self-reciprocal, from which the desired RM matrices can be efficiently constructed for all feasible parameters.
Kantowski-Sachs cosmological model: a general equation of state
Authors: Gonçalves S.V.B. , Silva B.B. 
Published: August 2022

Abstract
In this work we present a review of the calculations of traditional articles dealing with homogeneous and anisotropic cosmological models, particularly the Kantowski-Sachs cosmological model. As an innovative contribution, we calculate an exact solution to the field equations with a general expression of the equation of state for the material content of the universe, $p = \alpha\rho$. We obtain the expressions for energy density and pressure in this general case. We also study the case involving a scalar field. We studied, in particular, the following perfect fluids: dust ($p = 0$), stiff matter ($p = \rho$), radiation ($p = \rho/3$), cosmic strings ($p = -\rho/3$) and vacuum ($p = -\rho$).
An efficient numerical method on modified space-time sparse grid for time-fractional diffusion equation with nonsmooth data
Authors: Zhu Bi-Yun , Li Xue-Yang , Xiao Ai-Guo 
Published: August 2022

Abstract
In this paper, we focus on developing a high efficient algorithm for solving d-dimension time-fractional diffusion equation (TFDE). For TFDE, the initial function or source term is usually not smooth, which can lead to the low regularity of exact solution. And such low regularity have a marked impact on the convergence rate of numerical method. In order to improve the convergence rate of the algorithm, we introduce the space-time sparse grid (STSG) method to solve TFDE. In our study, we employ the sine basis for spatial discretization, and all the sine coefficients can be divided into several levels. The sine coefficients with different levels are discretized by temporal basis with different scales, which can lead to the STSG method. Under certain conditions, the function approximation on standard STSG can achieve the accuracy order O(2-Jd) with O(2JJ) degrees of freedom (DOF) for d=1 and O(2Jd) DOF for d>1, where J denotes the maximal level of sine coefficients. However, the standard STSG is not suitable to simulate the singularity of TFDE at the initial time. To overcome this, we integrate the full grid into the STSG, and obtain the modified STSG. Then, the modified STSG is used to construct the fully discrete scheme for solving TFDE. The great advantage of STSG method can be shown in the comparative numerical experiment.Mathematics Subject Classification (2010) 35R11 · 65M70 · 65T40 · 68Q25
Intra-arterial chemotherapy plus BCG, a promising combination adjuvant treatment for high-risk NMIBC
Authors: Luo Shuhang , Yang Rui , Huang Gaowei , Wusimanjiang Wumier , Lei Jiahao , Liu Jinwen , Lin Shengjie , Liu Zhoujing , Chen Lingwu , Chen Junxing , Huang Bin 
Published: August 2022

Abstract
Purpose To develop a novel combination therapy for high-risk non-muscle-invasive bladder cancer (NMIBC) after transurethral resection of bladder tumor (TURBT), namely, intra-arterial chemotherapy (IAC) plus BCG immunotherapy, and to compare the feasibility and safety of the two therapies. Materials and methods A retrospective study was conducted on the data of 119 patients who were diagnosed with high-risk NMIBC and underwent TURBT in the past five years. Those who did not complete the treatment were excluded, and the remaining 98 patients were divided into two groups: both groups received intravesical BCG immunotherapy, while the BCG+IAC group received 4 courses of extra intra-arterial chemotherapy. Clinical and follow-up data were processed using statistical software.Result The recurrence rate was 22.2% in the BCG+IAC group and 35.8% in the BCG group, whereas the progression rates were 8.9% and 24.5%, respectively. In the Kaplan-Meier plot, a statistically significant difference was observed with respect to recurrence-free survival (p=0.025), as well as the progression-free survival of the two groups was similar (p=0.019). 22.2% of the patients with adverse effects of IAC and 79.6% of patients suffered from adverse reactions to BCG immunotherapy, and most of the adverse effects were mild and tolerable. Univariate and multivariate analysis indicated that multifocal and treatment were independent risk factors for recurrence, while the history of recurrence and treatment were independent risk factors for progression.Conclusion IAC could be a promising auxiliary treatment for BCG immunotherapy in decreasing the recurrence and progression rate of high-risk NMIBC with little additional toxicity.Date of registration:10th, April 23, 2022. TRN: ChiCTR2200058555, retrospectively registered
Prognostic Value of Peritoneal Cytology in Stage I Serous and Clear Cell Carcinoma of the Endometrium
Authors: Yang Jie , Xiang Yang , Cao Dongyan , Wu Ming , Yang Jiaxin 
Published: August 2022

Abstract
OBJECTIVE: To investigate the relation of malignant peritoneal cytology and survival outcomes in patients who underwent primary staging surgery for stage I uterine serous (USC) or clear cell carcinoma (UCCC). METHODS: In this retrospective analysis, patients with stage I USC or UCCC who underwent staging surgery between 2010 - 2020 from the Peking Union Medical College Hospital were identified and reviewed.RESULTS: A total of 101 patients were included and 11 patients had malignant cytology (10.9%). None of the covariates were associated with an increased likelihood of malignant peritoneal cytology. The median follow-up time was 44 months (range 6-120). A total of 11 (10.9%) patients developed recurrence: 6 (54.4%) in the malignant cytology group and 5 (5.6%) in the comparative group. Patients with malignant cytology had a higher likelihood of peritoneal recurrence and shorter time to relapse (13 vs 38 months, p=0.022), as compared to patients with negative cytology. In univariate analysis, malignant cytology and serous histology had worse progression free survival (PFS) and overall survival (OS) (all, p < 0.05). Advanced age (>60 years old), higher stage (IB), and no omentectomy were additionally associated with inferior OS (all, p < 0.05). In sensitive analysis, the detrimental effects of malignant cytology on survival were more prominent in patients over 60 years old, those with serous histology, stage IB disease, and those who received hysteroscopy as a diagnostic test. CONCLUSION: Stage I USC or UCCC patients with malignant peritoneal cytology had higher recurrence and inferior survival.
Prosthetic valve endocarditis secondary to Tropheryma whipplei in a patient with chronic polyarthritis
Authors: Kahn Mauricio J. , Ennis David M. , Delgado Dennis G. 
Published: August 2022

Abstract
Background: Whipple’s disease is a chronic multisystemic infectious disease that rarely presents as culture-negative endocarditis. Most patients reported with Tropheryma whipplei endocarditis involve a native valve and few describe prosthetic valve disease.Case presentation: A patient with chronic polyarthritis and previous mitral valve replacement developed decompensated heart failure without fever. Transesophageal echocardiography revealed a prosthetic mitral valve vegetation and he underwent prosthetic mitral valve replacement. Blood and prosthetic mitral valve cultures were unrevealing. Broad-range polymerase chain reaction (PCR) of the extracted valve and subsequent Periodic-acid-Schiff (PAS) staining established the diagnosis of T. whipplei prosthetic valve endocarditis.Conclusion: Whipple’s disease may present as culture-negative infective endocarditis and affect prosthetic valves. Histopathology with PAS staining and broad-range PCR of excised valves are essential for the diagnosis. Greater clinical awareness and implementation of these diagnostic procedures should result in an increased reported incidence of this rare disease.
Harmonizing DevOps Taxonomies - A Grounded Theory Study
Authors: Díaz Jessica , Pérez Jorge , Alves Isaque , Kon Fabio , Leite Leonarado , Meirelles Paulo , Rocha Carla 
Published: August 2022

Abstract
Context: DevOps responds to the growing need of companies to streamline the software development process and, thus, have experienced a widespread adoption in the past few years. However, successful adoption of DevOps requires companies to address important cultural and organizational changes. Understanding the organizational structure and characteristics of teams adopting DevOps is key, and comprehending the existing theories and representations of team taxonomies is critical to guide companies in a more systematic and structured DevOps adoption process. Objective: This paper presents empirical research on the structure of DevOps teams in software-producing organizations. The goal is to better understand the organizational structure and characteristics of teams adopting DevOps by harmonizing the existing knowledge. Method: To do this, we conducted a grounded theory study, analyzing existing studies on DevOps teams and taxonomies. Results: From the analysis, we built a substantive and analytic theory of DevOps taxonomies. The theory is substantive in that the scope of validity refers to the ten primary studies processed and analytic in that it analyzes “what is” rather than explaining causality or attempting predictive generalizations. A public repository with all the data related to the products resulting from the analysis and generation of the theory is available. Conclusions: We built a theory on DevOps taxonomies and tested whether it harmonizes the existing taxonomies, i.e., whether our theory can instantiate the others. This is the first step to define which taxonomies are best suited to approach DevOps culture and practices according to the companies’ objectives and capabilities.
Underwater Mucosectomy to Treat Colon Mesenchymal Leiomyoma Lesion - a Rare Case Report
Authors: Guedes Hugo Gonçalo , Viana Beatriz Oliveira , Vieira Isabela Santos Rossigneux , Rassi Carlos Henrique Reis Esselin , Silveira Thales Parenti 
Published: August 2022

Abstract
Introduction: Leiomyomas are rare on the colon and represent only 3% of cases. They are frequently asymptomatic and are often found accidentally during colonoscopic examination. Colonic leiomyomas have an excellent prognosis and do not tend to recur after removal.Case: We report a rare case of submucosal leiomyoma, in the colon, diagnosed during a routine colonoscopy and resected by underwater mucosectomy.Conclusion: Although rare, colonic leiomyomas are a differential diagnosis for pre-cancerous epithelial lesions and should be considered when a polyp is found. In this case report we present what is likely the first case to be successfully resected through underwater mucosectomy.