bluuebunny/crossref_metadata_2025_split huggingface dataset:
Socioeconomic inequality in the prevalence of low birth weight and its associated determinants in Bangladesh
Authors: Alam Md. Jahangir , Islam Md. Merajul , Maniruzzaman Md. , Ahmed N. A. M. Faisal , Tawabunnahar Most. , Rahman Md. Jahanur , Roy Dulal Chandra , Mydam Janardhan 
Published: October 2022

Background and objectiveLow birth weight (LBW) is a major risk factor of child mortality and morbidity during infancy (0–3 years) and early childhood (3–8 years) in low and lower-middle-income countries, including Bangladesh. LBW is a vital public health concern in Bangladesh. The objective of the research was to investigate the socioeconomic inequality in the prevalence of LBW among singleton births and identify the significantly associated determinants of singleton LBW in Bangladesh.Materials and methodsThe data utilized in this research was derived from the latest nationally representative Bangladesh Demographic and Health Survey, 2017–18, and included a total of 2327 respondents. The concentration index (C-index) and concentration curve were used to investigate the socioeconomic inequality in LBW among the singleton newborn babies. Additionally, an adjusted binary logistic regression model was utilized for calculating adjusted odds ratio and p-value (<0.05) to identify the significant determinants of LBW.ResultsThe overall prevalence of LBW among singleton births in Bangladesh was 14.27%. We observed that LBW rates were inequitably distributed across the socioeconomic groups (C-index: -0.096, 95% confidence interval: [-0.175, -0.016],P= 0.029), with a higher concentration of LBW infants among mothers living in the lowest wealth quintile (poorest). Regression analysis revealed that maternal age, region, maternal education level, wealth index, height, age at 1st birth, and the child’s aliveness (alive or died) at the time of the survey were significantly associated determinants of LBW in Bangladesh.ConclusionIn this study, socioeconomic disparity in the prevalence of singleton LBW was evident in Bangladesh. Incidence of LBW might be reduced by improving the socioeconomic status of poor families, paying special attention to mothers who have no education and live in low-income households in the eastern divisions (e.g., Sylhet, Chittagong). Governments, agencies, and non-governmental organizations should address the multifaceted issues and implement preventive programs and policies in Bangladesh to reduce LBW.
Dynamics of type IV collagen 7S fragment on eradication of HCV with direct antiviral agents: Prognostic and metabolomic impacts
Authors: Yamataka Karin , Chu Po-sung , Koda Yuzo , Taniki Nobuhito , Morikawa Rei , Yoshida Aya , Noguchi Fumie , Kasuga Ryosuke , Tabuchi Takaya , Ebinuma Hirotoshi , Kanai Takanori , Nakamoto Nobuhiro 
Published: October 2022

BackgroundLiver fibrosis is one of the cardinal clinical features of chronic hepatitis C (CHC). However, the mechanisms underlying the evolution and reversion of liver fibrosis after hepatitis C virus (HCV) eradication and their relationship with clinical outcomes and metabolic alterations are not fully elucidated. Whether any non-invasive fibrosis marker can predict prognosis is unknown.MethodsBetween October 2014 and September 2019, 418 patients with CHC or compensated cirrhosis with HCV were prospectively recruited in this observational study. 326 patients that were successfully eradicated with interferon-free direct antiviral agents (IFN-free DAAs) were analyzed. Peri-treatment dynamics of serum levels of type IV collagen 7S fragment (4COL7S), a fibrosis marker, and subsequent clinical outcomes, including hepatic decompensation, newly emerged hepatocellular carcinoma (HCC), and all-cause mortality were analyzed.ResultsTen (3.1%) patients died during the observation period. 4COL7S-defined fibrosis progression (n = 97, 29.8%) at SVR was significantly correlated with worse all-cause mortality post-SVR (P= 0.0062) but not with the probability of newly emerged HCC (P= 0.24). Prognostic tendency was more prominent in patients with advanced fibrosis (P< 0.0001). 4COL7S-defined fibrosis progression at SVR and a baseline platelet count less than 10×104/μL were significantly predicted all-cause mortality (P= 0.0051). In exploratory analyses, a decreased 4COL7S at the end of treatment was correlated with a matrix-degrading phenotype that showed higher serum metalloproteinase to tissue inhibitors of metalloproteinase-1 ratios and characteristic metabolic fingerprints such as increased butyrate, some medium-chain fatty acids, anabolic amino acids, and decreased uremia toxins.ConclusionsPeri-treatment dynamics of serum 4COL7S, a non-invasive fibrosis marker, predict prognosis. Non-invasive fibrosis markers may be useful biomarkers for risk stratification post-SVR.
Pengaruh herding, overconfidence, dan endowment bias pada keputusan investasi investor pasar modal
Authors: Theressa Thea Diva , Armansyah Rohmad Fuad 
Published: October 2022

Investment is one of the steps to get a financial advantage in the future. Investment decision-making involves thinking about action to make decisions. This study aims to examine the effect of Herding bias, Overconfidence bias, and Endowment bias on Investors' Investment Decision Making in the Capital Market. The sample consists of 150 respondents with the characteristics of being an active investor for at least 1 year in the capital market, having a minimum age of 17 years, and being Indonesian citizens. The sample was taken by purposive sampling method through the distribution of electronic questionnaires to investors who have joined the capital market. The data were analed using Structural Equating Modeling (SEM) on Partial Least Square (PLS). The results of this study indicate that herding bias, overconfidence bias, and endowment bias affect investors' investment decision-making. The partial test supports this results, showing a positive effect of each variable herding bias, overconfidence bias, and endowment bias on investment decision variables. This study has implications for investment decision-makers with millennial demographics regarding financial bias behavior in the midst of information development, so it is important to base the fundamental and technical analysis on decision-making.
Développer la compétence interculturelle en classe de français langue étrangère à travers le roman noir Derrière les panneaux il y a des hommes de Joseph Incardona
Authors: Ráčková Lucia , Schmitt François , Zázrivcová Monika 
Published: October 2022

Current research on interculturality in foreign language teaching focuses on the development of the intercultural personality of the learner based on his social representations. In this context, the introduction of crime fiction in French foreign language teaching makes it possible to take the complexity of the human personality more efficiently into account when developing the intercultural competence of the learner. Based on a thematic analysis of the novel Derrière les panneaux il y a des hommes (Behind the Panels There Are Men) by Joseph Incardona, which aims at highlighting the references to French culture in the text, and from a linear analysis centered on the characters and their complex personalities, the article proposes to apply the cultural and intercultural approaches of language didactics to literature. In this way, in order to develop cultural competence, the learners first learn to identify the cultural clues referring to French society in the text. Then, they learn to adopt a positive attitude of openness towards others through the characters of the novel to develop their intercultural competence.
Intuitive and immersive teleoperation of robot manipulators for remote decontamination
Authors: Fennel Michael , Zea Antonio , Hanebeck Uwe D. 
Published: October 2022

Abstract
Worker safety is one of the most important aspects of decontamination tasks in hazardous environments. This motivates the development of (semi-) autonomous robotic systems that can be teleoperated from a safe distance using simple commands such as ‘move the manipulator over there and grab’. In this paper, we introduce a new control station concept called Digital Twin Control System aimed at robots with manipulator arms. It consists of three components: (1) A unified communication interface that abstracts the remote robot’s functionalities into easy-to-use interaction modes, (2) an immersive visualization and assistant system to operate the interface, and (3) a haptic rendering system that can simulate arbitrary robot arms. We demonstrate how the proposed system can be used by untrained operators to pick up contaminated objects remotely in a test scenario.
Use and misuse of ultrasound in obstetrics with reference to developing countries
Authors: Kurjak Asim , Medjedovic Edin , Stanojević Milan 
Published: October 2022

Abstract
Maternal and neonatal health is one of the main global health challenges. Every day, approximately 800 women and 7,000 newborns die due to complications during pregnancy, delivery, and neonatal period. The leading causes of maternal death in sub-Saharan Africa are obstetric hemorrhage (28.8%), hypertensive disorders in pregnancy (22.1%), non-obstetric complications (18.8%), and pregnancy-related infections (11.5%). Diagnostic ultrasound examinations can be used in a variety of specific circumstances during pregnancy. Because adverse outcomes may also arise in low-risk pregnancies, it is assumed that routine ultrasound in all pregnancies will enable earlier detection and improved management of pregnancy complications. The World Health Organization (WHO) estimated in 1997 that 50% of developing countries had no access to ultrasound imaging, and available equipment was outdated or broken. Unfortunately, besides all the exceptional benefits of ultrasound in obstetrics, its inappropriate use and abuse are reported. Using ultrasound to view, take a picture, or determine the sex of a fetus without a medical indication can be considered ethically unjustifiable. Ultrasound assessment when indicated should be every woman’s right in the new era. However, it is still only a privilege in some parts of the world. Investment in both equipment and human resources has been clearly shown to be cost-effective and should be an obligatory step in the improvement of health care. Well-developed health systems should guide developing countries, creating principles for the organization of the health system with an accent on the correct, legal, and ethical use of diagnostic ultrasound in pregnancy to avoid its misuse. The aim of the article is to present the importance of correct and appropriate use of ultrasound in obstetrics and gynecology with reference to developing countries.
Rice yield grown in different fertilizer combination and planting methods: Case study in Buru Island, Indonesia
Authors: Hindersah Reginawanti , Kalay Agusthinus Marthin , Talahaturuson Abraham 
Published: October 2022

Abstract
Rice productivity in the tropics largely depends on fertilizers as soils are commonly low in nitrogen and phosphorus. Some farmers in this region cultivate rice using the hand-broadcast method, which has resulted in a low yield. Therefore, this on-farm experiment was conducted to compare the performance and yield of broadcasted and transplanted rice production systems under different fertilizer combinations. The experimental was set up in a split plot design with six combination treatments and seven replications. The main plots were planting methods comprised of transplanting and broadcasting. The subplots were a combination of NPK fertilizer, urea, and biofertilizer (BF) with and without compost, while the control treatment was NPK fertilizer and urea. The BF contained nitrogen fixer bacteria and phosphate solubilizer microbes. The results showed that fertilizer combination increased shoot height, root length, shoot and root dry weight (RDW), root-to-shoot ratio (R/S), tiller number, 1,000-grain weight, and yield but did not affect clump number. In addition, the planting method affected the parameters except for R/S and 1,000-grain weight. The yield of transplanted rice grown with NPK fertilizer and urea was 17.5% higher than that of the broadcasting method. Incorporation of chemical fertilizer combined with compost and BF resulted in a comparable yield; transplanted rice yield was only 2.18% more than broadcasted. This showed that diverse fertilizer application is needed to minimize the yield gap between broadcasted and transplanted rice.
Cardiovascular disease, mortality and exposure to particulate matter (PM): a systematic review and meta-analysis
Authors: Mohammadi Mohammad Javad , Fouladi Dehaghi Behzad , Mansourimoghadam Sara , Sharhani Asaad , Amini Payam , Ghanbari Saeed 
Published: October 2022

Abstract
One of the main factors that causes health effects in humans such as hospital admissions for cardiovascular disease (HACVD), respiratory disease (RD), lung function, cardiovascular mortality (MCVD), lung cancer, and increased mortality is air pollution especially particulate matter (PM). This a systematic review and meta-analysis aims to investigate the effects of particulate matter on the occurrence of cardiovascular disease and mortality. A systematic review and meta-analysis of the literature was done from 2011 to 2021 based on various databases. Based on the result of this study, subgroup analysis based on temperature conditions showed a different estimation in cold cities (6.24, UR (4.36–8.12)), moderate cities (4.86, UR (3.57–6.15)) and warm cities (8.96, UR (7.06–10.86)). Test of group differences showed a significant difference (Q=12.22, p-value<0.001). There was publication bias among the studies (the Egger’s test; (Z=14.18, p<0.001)). According result study pooled estimation of AP% for MCVD from the random-effect meta-analysis based on DerSimonian-Laird model, overall is 5.04, UR (3.65–6.43) (Figure 4). Subgroup analysis based on temperature conditions showed the estimation in cold cities (5.47, UR (3.97–6.97)) and moderate cities (4.65, UR (0.54–8.77)). Test of group differences showed a non-significant difference (Q=0.13, p-value=0.71). There was no publication bias among the studies (the Egger’s test; (Z=0.82, p=0.376)). Exposed to air pollutants and particulate matter can be increase the risk of cardiovascular disease, respiratory disease, and cardiovascular mortality.
Effects of Visual Deprivation on Remodeling of Nodes of Ranvier in Optic Nerve
Authors: Santos Erin N. , Huffman William C. , Fields R. Douglas 
Published: October 2022

AbstractOligodendrocytes, the myelinating cells of the CNS, promote rapid action potential conduction along axons. Changes in the geometry of gaps between myelin segments, known as nodes of Ranvier, affect the conduction speed of neuronal impulses and can ultimately alter neural synchronization and circuit function. In contrast to synaptic plasticity, much less is known about how neural activity may affect node of Ranvier structure. Recently, perinodal astrocytes have been shown to remodel nodes of Ranvier by regulating thrombin proteolysis, but it is not known whether neural activity influences this process. To test this hypothesis, we used transgenic mice with astrocytic expression of a dominant-negative vesicle-associated membrane protein 2 ([gfap]dnVAMP2) to reduce exocytosis of thrombin inhibitors, modulating astrocytic regulation of paranodal loop attachment to induce nodal remodeling, under normal conditions and in adult mice maintained in darkness from postnatal day 40 (P40) to P70. This mechanism of nodal lengthening proceeded normally following binocular visual deprivation (BVD). The effect of BVD on nodal plasticity in animals with unimpaired astrocyte function has not been previously investigated. We find that when exocytosis from astrocytes was unimpaired, nodal gap length was not altered by BVD in adult mice. We conclude that if perinodal astrocytes participate in activity-dependent myelin remodeling through exocytosis, then, as with synaptic plasticity in the visual system, the process must be driven by alterations in neuronal firing other than those produced by BVD.
Conditional Degradation of UNC-31/CAPS Enables Spatiotemporal Analysis of Neuropeptide Function
Authors: Cornell Rebecca , Cao Wei , Liu Jie , Pocock Roger 
Published: October 2022

Neuropeptide release from dense-core vesicles inCaenorhabditis elegansis promoted by UNC-31, ortholog of the calcium-dependent activator protein for secretion (CAPS). Loss of UNC-31 causes multiple phenotypes inC. elegansincluding reduced motility, retention of late-stage eggs, and reduction in evoked synaptic release. However, the ability to analyze UNC-31 function over discrete timescales and in specific neurons is lacking. Here, we generated and validated a tool to enable UNC-31 expression and spatiotemporal functional analysis. We show that endogenously tagged UNC-31 is expressed in major ganglia and nerve cords from late embryonic stages through to adult. Using the auxin-inducible degradation system, we depleted UNC-31 postembryonically from the hermaphrodite nervous system and revealed defects in egg laying, locomotion, and vesicle release that were comparable to those inunc-31null mutant animals. In addition, we found that depleting UNC-31 specifically from the BAG sensory neurons causes increased intestinal fat storage, highlighting the spatial sensitivity of this system. Together, this protein degradation tool may be used to facilitate studies of neuropeptide function at precise cellular and temporal scales.SIGNIFICANCE STATEMENTAnimal behavior and physiology is controlled by neuropeptides that are released from specific neuronal sources. The ability to dissect discrete neuropeptide functions requires precise manipulation of neuropeptide release. We have developed and validated a tool that enables precise spatiotemporal regulation of neuropeptide release that will enable researchers to examine neuropeptide function at exceptional resolution.
Early Effect of the Circular Model of Kidney Allocation in the United States
Authors: Puttarajappa Chethan M. , Hariharan Sundaram , Zhang Xingyu , Tevar Amit , Mehta Rajil , Gunabushanam Vikraman , Sood Puneet , Hoffman William , Mohan Sumit 
Published: October 2022

Significance Statement
To reduce geographic disparities in kidney transplantation, the United States implemented a new model of deceased donor kidney allocation in March 2021. The new model’s effect on transplant logistics and kidney utilization is unknown. Using data from the Scientific Registry of Transplant Recipients, this study found an increase in transplants among highly sensitized patients and patients with long dialysis duration. However, cold ischemia time after implementation of the new allocation policy increased significantly, with a suggestion of an increase in kidney discards. Given that the policy was implemented during the coronavirus disease 2019 pandemic, which also affected transplant practices, there is need for continued monitoring for potential unintended consequences of the new policy, along with efforts to mitigate them.

Background
In March 2021, the United States implemented a new kidney allocation system (KAS250) for deceased donor kidney transplantation (DDKT), which eliminated the donation service area-based allocation and replaced it with a system on the basis of distance from donor hospital to transplant center within/outside a radius of 250 nautical miles. The effect of this policy on kidney discards and logistics is unknown.

Methods
We examined discards, donor-recipient characteristics, cold ischemia time (CIT), and delayed graft function (DGF) during the first 9 months of KAS250 compared with a pre-KAS250 cohort from the preceding 2 years. Changes in discards and CIT after the onset of COVID-19 and the implementation of KAS250 were evaluated using an interrupted time-series model. Changes in allocation practices (biopsy, machine perfusion, and virtual cross-match) were also evaluated.

Results
Post-KAS250 saw a two-fold increase in kidneys imported from nonlocal organ procurement organizations (OPO) and a higher proportion of recipients with calculated panel reactive antibody (cPRA) 81%–98% (12% versus 8%; P<0.001) and those with >5 years of pretransplant dialysis (35% versus 33%; P<0.001). CIT increased (mean 2 hours), including among local OPO kidneys. DGF was similar on adjusted analysis. Discards after KAS250 did not immediately change, but we observed a statistically significant increase over time that was independent of donor quality. Machine perfusion use decreased, whereas reliance on virtual cross-match increased, which was associated with shorter CIT.

Conclusions
Early trends after KAS250 show an increase in transplant access to patients with cPRA>80% and those with longer dialysis duration, but this was accompanied by an increase in CIT and a suggestion of worsening kidney discards.
A Global Catalog of Calibrated Earthquake Locations
Authors: Bergman Eric A. , Benz Harley M. , Yeck William L. , Karasözen Ezgi , Engdahl E. Robert , Ghods Abdolreza , Hayes Gavin P. , Earle Paul S. 
Published: October 2022

Abstract
We produced a globally distributed catalog of earthquakes and nuclear explosions with calibrated hypocenters, referred to as the Global Catalog of Calibrated Earthquake Locations (GCCEL). This dataset currently contains 18,782 events in 289 clusters with &gt;3.2 million arrival times observed at 19,258 stations. The term “calibrated” refers to the property that the hypocenters are minimally biased by unknown Earth structure. In addition, we calculate uncertainties using empirically determined variability of the arrival-time data itself, specific to each calibrated cluster of hypocenters. Outliers in the arrival-time dataset are removed based on measured variability of the data. In each cluster, we estimate the empirically determined uncertainty for each set of station-phase arrival times. We use a version of the hypocentroidal decomposition multiple event relocation algorithm specifically adapted for calibrated relocations of clusters of seismic events. Most clusters are calibrated by fitting the subset of direct crustal first arrivals (Pg and Sg) with a locally appropriate travel-time model to estimate the cluster hypocentroid. A few clusters are calibrated by aligning the pattern of relative locations in space and time with one or more events for which a ground-truth hypocenter is available from an independent source with known uncertainty, such as a nuclear explosion. Epicentral uncertainties in GCCEL typically range from 1 to 5 km with a 90% confidence interval. Most events have depth constraint from one or more sources, usually with an uncertainty of ≤5 km. GCCEL is a significant resource for research at local, regional, and global scales because it provides minimally biased absolute hypocenters, meaningful associated error estimates, and curated arrival times as a reference dataset that can be used as prior constraints in the development of new regional, national, and global earthquake catalogs; validation of new location techniques; and the generation of advanced Earth models.