bluuebunny/crossref_metadata_2025_split huggingface dataset:
An automated network slicing at edge with software defined networking and network function virtualization – A federated learning approach
Authors: Rakkiannan Thamilselvan , Ekambaram Gothai , Palanisamy Natesan , Ramasamy Rajalaxmi Rajammal , Muthusamy Suresh , Loganathan Ashok Kumar , Panchal Hitesh , Thangaraj Kokilavani , Ravindaran Ashok Kumar 
Published: July 2022

Abstract
Network slicing allows heterogeneous applications can be launched across different domain using virtualized resources. The virtualized resources are created on the physical infrastructure. The orchestrator is essential for coordination of network slice management. The overhead in the slice orchestrator is reduced by distributed approach. The slice template act as a design specification template for the creation of network slices. This template can be predicted using federated learning, in which local models are trained with the generated data and global model is trained with local model parameters. Then the global parameters are updated in the local model for further learning. The federated model uses the SDN capability to learn the local model data distribution and hence enhance global SDN federated controller prediction accuracy for network slices. This process can be automated with the help of slice template with the predicted pattern. The parameters of the slice template are directly proportional to the performance of the slice orchestrator and prediction of future slice demands. The edge devices with its local model communicate with the global SDN federated model to satisfy the requirement of dynamic network slicing. The request on-demand services can be provided as virtual network function using network function virtualization. The optimal resource allocation for the requested slice can be done with statistical modeling of observed traffic and autoscaling can be carried out. Experimental studies reveal that the proposed network slicing with federated approach minimal response time with maximal orchestrator scalability.
Magnetic nanocellulose: Influence of structural features on conductivity and magnetic properties
Authors: Mustapić Mislav , Bafti Arijeta , Glumac Zvonko , Pavić Luka , Skoko Željko , Šegota Suzana , Klaser Teodoro , Nedeljković Robert , Amiralian Nasim , Masud Mostafa , Shahriar Md Hossain , Yamauchi Yusuke 
Published: July 2022

Abstract
Magnetic cellulose (MC) is prepared by hydrolysis of iron precursors in an aqueous dispersion of cellulose nanofibres. A thin, flexible film was then prepared by removing the water and drying the sample in a hot press at 110°C followed by the removal of the water. Structural analysis of MC was performed and correlated with the measurement of electromagnetic properties. The magnetic cellulose showed high magnetic saturation of 68 emu/g with characteristic superparamagnetic behaviour, and conductivity in a range of semiconductors, with an increase of DC conductivity with increasing temperature. Modification of cellulose with Fe3O4 has a positive effect on the DC conductivity and lower limit that needs to be exceeded to achieve a stable and sustainable conductivity in the range of ~5-20 ×10-9 (Ω cm)-1 @30 °C is 65 wt% of the Fe3O4 for studied MC composites. The surface roughness of the magnetic cellulose shows a dynamic change with increasing temperature, which is closely related to the enhancement of MC conductivity. A theoretical model of the conductivity is calculated based on continuous 2D percolation and shows an interesting agreement with the experimental results.
PDGFRB and NOTCH3 mutations are detectable in a wider range of pericytic tumors, including myopericytomas, angioleiomyomas, glomus tumors, and their combined tumors
Authors: Iwamura Ryuji , Komatsu Kazuki , Kusano Midori , Kubo Chisachi , Inaba Yuna , Shiba Eisuke , Nawata Aya , Tajiri Ryosuke , Matsuyama Atsuji , Matoba Hisanori , Koga Kaori , Takeda Maiko , Itami Hiroe , Hisaoka Masanori 
Published: July 2022

Abstract

Pericytic tumors are subclassified as myopericytomas, myofibromas, angioleiomyomas, and glomus tumors according to the current World Health Organization classification and form a continuous morphological spectrum including those with combined morphology. However, no widely accepted criteria for classifying tumors with combined morphology are available. Recent studies have identified platelet-derived growth factor receptor-beta (PDGFRB) gene mutations in a subset of myofibromas, myopericytomas, and myopericytomatoses, but not in angioleiomyomas. NOTCH receptor 3 (NOTCH3) mutations have been reported in a subset of infantile myofibromatoses. We investigated PDGFRB and NOTCH3 mutations in 41 pericytic tumors of variable morphology, including some combined forms, to assess their potential role in classifying pericytic tumors. Our results show these mutations to be present in a variety of pericytic tumors, such as myopericytomas (PDGFRB, 3/11; NOTCH3, 4/11), myopericytomatoses (1/2, 1/2), myofibromas (3/6, 0/6), angioleiomyomas (2/13, 3/13), and glomus tumors (5/9, 1/9). Point mutations were identified in three tumors in PDGFRB exon 12 (Y562C, S574F, and G576S), twelve tumors in PDGFRB exon 14 (M655I, H657L, and N666K), and nine tumors in NOTCH3 exon 25 (A1480S/T, D1481N, G1482S, T1490A, E1491K, G1494S and V1512A). All PDGFRB mutations and NOTCH3 G1482S, T1490A and G1494S mutations were classified as ‘deleterious/damaging’ by more than four out of six pathogenicity prediction tools in silico. Five mutation-positive tumors, including myopericytoma-angioleiomyoma, myopericytomatosis-myofibroma, myofibroma-myopericytoma, and angioleiomyoma-myopericytoma, were of combined morphology. Thus, we found PDGFRB and NOTCH3 mutations to be detectable in a much wider variety of pericytic tumors than previously reported, and confirmed myopericytomas, myofibromas, angioleiomyomas, and glomus tumors as members harboring PDGFRB or NOTCH3 mutations. Our results thus suggest that PDGFRB or NOTCH3 mutations are not useful for subclassifying members of the pericytic tumor family.
Protection of haematopoietic progenitor cell donors: an updated overview of the European landscape
Authors: Worel Nina , Ibáñez Jacinto Sánchez , Bokhorst Arlinke , Chandrasekar Akila , Domínguez-Gil Beatriz , Cruz Jorge Gayoso , Kaminski Artur , Lomero Maria del Mar , López-Fraga Marta 
Published: July 2022

Abstract
Haematopoietic progenitor cell donation from bone marrow and mobilised peripheral blood obtained from related and unrelated donors is an established procedure. The donation process in general has proven to be safe, but in rare cases severe and even fatal events have been reported. The present study aimed at providing a description of the current situation of donor protection measures in Council of Europe member states. A specific questionnaire was developed to compile information on donation activities, graft sources, legal frameworks, donor protection measures, collection of donor outcome data, and long-term follow-up of paediatric and adult related and unrelated donors. The outcome of this survey served as a basis for elaborating the Recommendation CM/Rec(2020)6 of the Committee of Ministers to member States on establishing harmonised measures for the protection of haematopoietic progenitor cell donors.
User’s engagement through social media advertisements: a comparative study on micro-scale industry
Authors: Pal Sayak , Thilaka N , Tripathi Nitesh , Kayal Sharmila 
Published: July 2022

Abstract
Before Digital Media, there were limited avenues for small-scale business to promote their business, thus they were unable to scale up. But with the emergence of Digital Media technologies, democratic platforms such as Social Media became popular among these micro-scale enterprises as a medium for promotion as they were free and provided them a worldwide reach through networking. One of the obvious ways of assessing the caption of particular content on an Online platform is to assess user engagement. It helps in understanding the overall effectiveness of particular promotional content. For this purpose, Facebook and Instagram posts were analyzed for a specific period of time and a datasheet was prepared after rigorous observation and coding. The study concluded that to a large extent there is a significant positive relationship between user engagement and conversion rate. Also, higher forms of engagement i.e., comments and queries were seen in posts that confirmed purchase intention.
Machine Learning Prediction of Preterm Birth: An Analysis of Facility-Based Paper Health Records in Uganda
Authors: Memon Shaheen , Wamala Robert , Kabano Ignace 
Published: July 2022

Abstract
Purpose: Preterm Birth (PTB) is one of the leading causes of neonatal mortality in Uganda. Machine Learning (ML) can be used to identify women at risk of PTB in time for medical intervention and adequate preparation by mothers. Methods: We utilized data from paper-based maternal health records at Kawempe National Referral Hospital, Uganda. A case-control method was employed, where for every woman who experienced a PTB, a woman without PTB and delivered in the same day was selected as a control. Treatment of missing data was done using Random Forest imputation. Variable Importance was analyzed using Random Forest. The following classification methods were applied in the prediction of PTB: Logistic Regression (LR), Random Forest (RF), Decision Tree (DT), Support Vector Machine (SVM), K-Nearest Neighbors (KNN), and Naïve Bayes (NB). Performance of methods was investigated using prediction accuracy, sensitivity, and specificity. Results: 1,540 women were included in the study, where 770 women had experienced PTB, and 770 women formed the controls. According to variable importance analysis, number of antenatal care visits had the biggest impact on PTB. SVM had the highest accuracy in predicting PTB at 64% (sensitivity 64% and sensitivity 63%). Conclusions: Prediction of PTB using paper-based records in a developing country yielded similar results to studies done using electronic health records in developed countries. The predictive power could be low in this study due to fewer variables available from routinely collected ANC data. The inclusion of significant variables in the maternal records could potentially increase predictive power.
Glomerular mTORC1 activation was associated with podocytes to endothelial cells communication in Lupus Nephritis
Authors: Liu Xiaotian , Mao Zhaomin , Yuan Mo , Li Linlin , Tan Ying , Qu Zhen , Yu Feng 
Published: July 2022

Abstract

Objective
This study was initiated to evaluate the mammalian target of rapamycin (mTOR) signaling pathway involved in renal endothelial- podocyte crosstalk of lupus nephritis (LN) patients.
Methods
We compared the kidney protein expression patterns of 10 LN patients with severe endothelial- podocyte injury and 3 ones with moderate endothelial- podocyte injury on formalin-fixed paraffin-embedded kidney tissues using label-free liquid chromatography-mass spectrometry (LC-MS) for quantitative proteomics analysis. GO (Gene Ontology) enrichment analyses were performed based on protein intensity levels of differentially expressed proteins (DEPs) in each patient. Enriched mTOR pathway was selected, and the activation of mTOR complexes in renal biopsied specimens were further verified in 176 LN patients.
Results
Compared with the moderate group, 230 proteins were up-regulated and 54 proteins were down-regulated in severe group. Further GO enrichment analysis was enriched in the “positive regulation of mTOR signaling” pathway. The glomerular activation of mTORC1 was significantly increased in severe group than that in moderate group (P = 0.034) and it was located in podocytes and glomerular endothelial cells, respectively. The glomerular activation of mTORC1 was positively correlated with endocapillary hypercellularity (r = 0.289, P < 0.001) and significantly increased in patients with both endocapillary hypercellularity and FPW > 1240 nm (P < 0.001).
Conclusions
Glomerular mTORC1 was highly activated in patients with both glomerular endocapillary hypercellularity and podocytes injury, which might be involved in endothelial to podocyte communication in lupus nephritis.
Reservoir quality of upper Cretaceous Sarvak Formation in an oilfield located in Dezful Embayment, Southwestern Iran
Authors: Vakili Nazanin , Yazdjerdi Kouros , Swennen Rudy , ahmadi vahid 
Published: July 2022

Abstract
The Upper Cretaceous Sarvak Formation in the Zagros and the Persian Gulf (Southwestern Iran) forms an important reservoir succession. Oil reserves in Sarvak, together with Ilam Formations, make up one-fourth of the total reserves of Iran. This study aimed to determine the petrophysical parameters influencing the reservoir properties within the carbonate sequence of the Sarvak Formation and to identify its productive zones. The latter formation is dominantly composed of limestone and dolomite with subordinate shale units. The studied Sarvak succession has been subdivided into six zones based on petrophysical criteria, whereby zones 3 and 4 have the highest reservoir potential based on the low water saturation and low shale amounts. The main diagenetic processes identified include dolomitization, dissolution, and cementation. The latter process obviously destroys reservoir properties, while dolomitization and dissolution enhance reservoir properties. Measurement of shale volume indicates that its amount is less than four percent of the rock volume. The dominant clay mineral consists of illite or mixed clay minerals with montmorillonite, and their presence is related to well depth and pressure.
Increased storage during inhibition of ethylene biosynthesis in apples using 1-methylcyclopropene and calcium chloride
Authors: Kim Wu 
Published: July 2022

Abstract
Fruit tissue softening and quality decline limit its post-harvest life, cause mechanical damages during transfer and increase respiration. Exposure of fruits to ethylene gas reduces their quality and storage life. Bioregulators such as 1-methylcyclopropene, treatment with calcium chloride and their combination improve the qualitative properties of fruits by delaying their ripening and increasing their storage life. Effects of treatment with 1-methylcyclopropene and calcium chloride alone or in combination on post-harvest quality variations of French Delbarestivale apple were evaluated. Split-plot factorial experiments based on a fully random design were performed in triplicate. The main factor was the duration of storage at four levels with two-month intervals (60, 120, 180 and 240 days); the secondary factor was the combination of 1-methylcyclopropene treatment at three levels (control, 0.001 and 0.002 µl/l) and calcium chloride treatment at three levels (control with distilled water, 1 and 2%). Qualitative characteristics of the fruits and their ethylene levels during storage were measured. Based on the results, prolonging the storage time significantly reduced the fruit's acidity. The use of 1-methylcyclopropene and calcium chloride significantly increased the fruit tissue firmness and total soluble solids, and reduced ethylene generation during storage. Overall, the use of 1-methylcyclopropene and calcium chloride treatment increased the storage life of the Delbarestivale apple, decelerated the fruit’s biochemical alterations and maintained the shelf life of the fruit for a longer time.
Estrogen regulates PTEN to induce epithelial ovarian cancer cell proliferation using a two-pronged approach: genomic pathway and non-genomic pathway
Authors: Li Xiuwen , Miao Chunlei , Wang Lin , Liu Mengyan , Chang Huanchao , Tian Bo , Wang Di 
Published: July 2022

Abstract
Background
Epithelial ovarian cancer (EOC) has the highest mortality rate among malignant tumors in women and its occurrence and development are strongly linked to estrogen. Having identified the phosphatase and tensin homologue (PTEN) is a potent tumor suppressor regulating cell proliferation, migration, and survival. Although the role of PTEN in inhibiting cancer has long been emphasized, the role in estrogen-induced EOC is unclear.
Results
We got the following main results. (1) PTEN expression is decreased in EOC tissues. (2) Estrogen decreased PTEN expression in EOC cells via the estrogen receptor ESR1. (3) Knockdown of PTEN enhanced the proliferation and migration of SK-OV-3 cells by estrogen. (4) Estrogen induced phosphorylation of PTEN via the G-protein-coupled receptor (GPCR)-Protein kinase C (PKC) non-genomic pathway. (5) Inhibiting the phosphorylation of PTEN weakened the proliferation and migration of SK-OV-3 cells by estrogen and decreased the phosphorylation of AKT and mammalian target of rapamycin (mTOR).
Conclusion
The data indicated that estrogen decreased PTEN expression level via the ESR1 genomic pathway and phosphorylated PTEN via the GPCR-PKC non-genomic pathway to activate the PI3K/AKT/mTOR signaling pathway, thereby determining the fate of epithelial ovarian cancer cells.
Victimization among adolescent children of female sex workers: findings from the Children of At-Risk Parents (CARP) study in Uganda
Authors: Ouma Simple , Abbo Catherine , Natala Nakita , McCoy Molly , Kroupina Maria 
Published: July 2022

Abstract
Background: Female sex workers (FSWs) live in high-risk environments, experience high levels of adversity and have multigenerational trauma that can negatively affect their children, yet there is only minimal information on victimization among children of FSWs. This study aimed to evaluate the association between maternal sex work and victimization among adolescents in Uganda.Methods: The sample consisted of 294 respondents to the Children of At-Risk Parents (CARP) study, a comparative cross-sectional quantitative study among adolescents in Northern Uganda. We collected data among 147 adolescent children (10-17 years) of FSWs and 147 adolescent children of non-FSWs. We screened for victimization using the Juvenile Victimization Questionnaire. The data were analyzed using STATA version 14. Results: The prevalence of lifetime victimization stood at 99.3% but on average, each adolescent experienced 12.4 out of 34 different victimizations. Significantly, the adolescent children of FSWs were exposed to more victimizations than their comparators (13.4 vs 11.5; p<0.01). Specifically, compared with the adolescent children of non-FSWs, more adolescent children of FSWs experienced kidnap (15.8% vs 4.8%; p<0.01), emotional abuse (65.8% vs 50.0%; p<0.05), neglect (37.4% vs 21.1%; p<0.01), physical intimidation (10.2% vs 4.1%; p<0.05), relational aggression (36.4% vs 18.4%; p<0.01), verbal aggression (68.7% vs 46.9%; p<0.001), sexual victimization (31.3% vs 17.7%; p<0.01), verbal sexual harassment (20.4% vs 5.4%: p<0.001), exposure to murder scene (42.9% vs 26.5%; p<0.01), witness to domestic violence (39.5% vs 26.5%; p<0.05), and witness to murder of relatives (31.3% vs 21.1%; p<0.05). Conversely, the adolescent children of non-FSWs reported more caregiver victimization (98.0 vs 92.5; p<0.05) than the adolescent children of FSWs. Conclusions: Disproportionately, children of FSWs are more likely to experience victimization than children of non-FSWs. Therefore, government and development partners must deliberately develop policies and programs targeting victimizations among children of FSWs.
Landscape composition influences colony growth in the tropical Asian stingless bees (Tetragonula fuscobalteata)
Authors: Wayo Kanuengnit , Leonhardt Sara D. , Chuttong Bajaree , Chelong Isma-ae , Bumrungsri Sara 
Published: July 2022

Abstract
Context
Pollination is an important ecosystem service for both crop and wild plants. In recent decades, many pollinators have been experiencing population declines due to land-use changes and intensified agriculture. However, effects of anthropogenic landscapes on bee pollinators in the tropics are still little investigated.
Objectives
We analyzed the effects of landscape composition on the colony weight as well as foraging activity and patterns of the tropical Asian stingless bee species Tetragonala fuscobalteata which is a vital generalist pollinator in Southeast Asia.
Methods
Twenty-eight colonies were established and monitored over a year in 19 mixed fruit orchards located along a gradient of human land-use intensity.
Results
Our results revealed that the colonies gained weight and increased their foraging activity over time across diverse landscapes including forest, agricultural, and urbanized areas, indicating that this bee species can well adapt to anthropogenic landscapes. Interestingly, T. fuscobalteata colonies also gained weight rapidly in orchards located in predominately agricultural landscapes with e.g. high proportions of rubber and oil palm plantations as well as in fruit orchards (such as rambutan, durian, coconut, banana). This positive effect was possibly due to mass flowering crops providing abundant resources, i.e., pollen and nectar, for a limited time. We also show that T. fuscobalteata foragers could rely on urbanized land (probably ornamental plants and some crops in home gardens and backyards) and wild plants in surrounding forest patches during non-flowering periods of crops.
Conclusions
Our findings thus indicate that the combined floral resource availability provided by heterogeneous anthropogenic landscapes, including agricultural fields, urbanized areas and forests, can sustain generalist pollinators.
Enhancement and mechanism of NFC doping on thermodynamic properties of insulating paper.
Authors: Zhang Yiyi , Deng Yuke , Wei Wenchang , Xu Chuqi , Zha Junwei 
Published: July 2022

Abstract
To enhance the thermodynamic properties of insulating paper, nano-fibrillated cellulose (NFC) was used to dope cellulose. The mechanical strength and thermal stability of cellulose insulating paper with different NFC doping mass fractions were analyzed by molecular dynamics simulations and experiments, and the optimal doping ratio of NFC was determined. The results showed that the mechanical properties, thermal conductivity, thermogravimetric properties, and glass transition temperature of NFC-modified insulating paper were improved compared with ordinary insulating paper. Among them, the maximum tensile strength after doping was 58.147 MPa, which was 20.040 MPa higher than the 30.107 MPa of the insulating paper before modification. The glass transition temperature was also 8.54°C higher than the 127.05°C before modification. Meanwhile, the mechanism of NFC doping enhancement on the insulating paper's thermodynamic properties was analyzed from the aspects of cohesive energy density, fractional free volume, and hydrogen bond. We believed that the doping of NFC can improve the thermodynamic properties of the insulating paper because it could enhance cellulose's interchain force, fill the insulating paper's internal pores, and increase the hydrogen bonding energy.