bluuebunny/crossref_metadata_2025_split huggingface dataset:
Selected Immunoendocrine Measures for Monitoring Responses to Training and Match Load in Professional Association Football: A Review of the Evidence
Authors: Springham Matthew , Newton Robert U. , Strudwick Anthony J. , Waldron Mark 
Published: November 2022

Biomarkers relating to player “stress balance,” immunological (ie, immunoglobulin-A), and hormonal (ie, testosterone and cortisol [T:C]) status are now commonly used in football. This article is our critical review of the scientific literature relating to the response of these measures to player load and their relationships with player health. The commonly reported relationship between immunoglobulin-A and training or match load highlights its sensitivity to changes in psychophysiological stress and the increased risk of compromised mucosal immunity. This is supported by its close relationship with symptoms of upper respiratory tract infection and its association with perceived fatigue in football players. Testosterone and cortisol concentrations and the testosterone–cortisol ratio are sensitive to changes in player load, but the direction of their response is often inconsistent and is likely influenced by player training status and non-sport-related stressors. Some evidence indicates that sustained periods of high training volume can increase resting testosterone and that sustained periods of low and high training intensity can increase resting cortisol, compromising the testosterone–cortisol ratio. These findings are noteworthy, as recent findings indicate interrelationships between testosterone, cortisol, and testosterone:cortisol and perceived measures of fatigue, sleep quality, and muscle soreness in football players. Variability in individual responses suggests the need for a multivariate and individualized approach to player monitoring. Overall, we consider that there is sufficient evidence to support the use of salivary immunoglobulin-A, testosterone, cortisol, and testosterone:cortisol measures as part of a multivariate, individualized player monitoring system in professional football.
Longitudinal and Cross-Sectional Association Between Gait Speed, Ankle Proprioception, and LE Numbness—Results From the Baltimore Longitudinal Study of Aging
Authors: Ko Seung-uk , Simonsick Eleanor M. , Jerome Gerald J. , Palchamy Elango , Ferrucci Luigi 
Published: November 2022

Mobility declines in older adults can be determined through monitoring longitudinal changes in gait speed. We examined longitudinal changes [in] ankle proprioception among those with and without baseline lower extremity numbness to develop a better understanding of mobility declines in healthy older adults. Participants included 568 adults (52.8% women) aged 60–98 years from the Baltimore Longitudinal Study of Aging. Larger ankle proprioception decreases during plantar flexion were found in the participants with lower extremity numbness compared with those without numbness (p = .034). Among participants with lower extremity numbness, slower baseline speeds from both usual and fast pace gait were associated with performance decline in ankle proprioception measured during ankle dorsiflexion (p = .039 and p = .004, respectively). Assisting older adults, especially those with lower extremity numbness, to maintain and improve ankle proprioception may help prevent mobility declines that have previously been considered age related.
Socioeconomic status and modification of atherosclerotic cardiovascular disease risk prediction: epidemiological analysis using data from the atherosclerosis risk in communities study
Authors: Henderson Kamal , Kaufman Brystana , Rotter Jason S , Stearns Sally , Sueta Carla A A , Foraker Randi , Ho P Michael , Chang Patricia P 
Published: November 2022

ObjectiveExamine whether the relationship between the pooled cohort equations (PCE) predicted 10-year risk for atherosclerotic cardiovascular disease (ASCVD) and absolute risk for ASCVD is modified by socioeconomic status (SES).DesignPopulation-based longitudinal cohort study—Atherosclerosis Risk in Communities (ARIC)—investigating the development of cardiovascular disease across demographic subgroups.SettingFour communities in the USA—Forsyth County, North Carolina, Jackson, Mississippi, suburbs of Minneapolis, Minnesota and Washington County, Maryland.ParticipantsWe identified 9782 ARIC men and women aged 54–73 without ASCVD at study visit 4 (1996–1998).Primary outcome measuresRisk ratio (RR) differences in 10-year incident hospitalisations or death for ASCVD by SES and PCE predicted 10-year ASCVD risk categories to assess for risk modification. SES measures included educational attainment and census-tract neighbourhood deprivation using the Area Deprivation Index. PCE risk categories were 0%–5%, >5%–10%, >10%-15% and >15%. SES as a prognostic factor to estimate ASCVD absolute risk categories was further investigated as an interaction term with the PCE.ResultsASCVD RRs for participants without a high school education (referent college educated) increased at higher PCE estimated risk categories and was consistently >1. Results indicate education is both a risk modifier and delineates populations at higher ASCVD risk independent of PCE. Neighbourhood deprivation did modify association but was less consistent in direction of effect. However, for participants residing in the most deprived neighbourhoods (referent least deprived neighbourhoods) with a PCE estimated risk >10%–15%, risk was significantly elevated (RR 1.65, 95% CI 1.05 to 2.59). Education and neighbourhood deprivation inclusion as an interaction term on the PCE risk score was statistically significant (likelihood ratio p≤0.0001).ConclusionsSES modifies the association between PCE estimated risk and absolute risk of ASCVD. SES added into ASCVD risk prediction models as an interaction term may improve our ability to predict absolute ASCVD risk among socially disadvantaged populations.
COVID-19 vaccine hesitancy in periconceptional and lactating women: a systematic review and meta-analysis protocol
Authors: Su Xianzhi , Lu Hua , Li Xinyun , Luo Mingli , Li Fangyuan , Zhang Qi 
Published: November 2022

IntroductionThe pandemic of COVID-19 disease has caused severe impact globally. Governments consider vaccination as an effective measure to control pandemic. However, many people have been hesitant to receive COVID-19 vaccine, particularly periconceptional and lactating women. Although research has indicated that pregnant women with COVID-19 are at a higher risk of adverse pregnancy and birth outcomes, as well as severe illness. There appears to be a lack of systematic and comprehensive evidence of the prevalence and determinants of COVID-19 vaccine hesitancy among periconceptional and lactating women. As a result, it has been essential to investigate periconceptional and lactating women’s vaccination views and behaviours. This study will review articles on vaccine hesitancy among periconceptional and lactating women to assess the impact of the COVID-19 vaccine hesitancy during the pandemic.Methods and analysisWe will systematically search observational studies from 1 November 2019 to 30 October 2021 in the following databases: Web of Science, PubMed, EMBASE, MEDLINE, Cochrane Library, EBSCO, WHO COVID-19 Database, CNKI and WanFang Database. The following medical subject headings and free-text terms will be used: “COVID-19 vaccines” AND “female” AND “vaccine hesitancy”. Eligibility criteria are as follows: population (women of reproductive age); exposure (currently pregnant, lactational or trying to get pregnant); comparison (general women who are not in preconception, gestation or lactation) and outcome (the rate of COVID-19 vaccine hesitancy). Article screening and data extraction will be undertaken independently by two reviewers, and any discrepancy will be resolved through discussion. We will use I2statistics to assess heterogeneity and perform a meta-analysis when sufficiently homogeneous studies are provided. We will explore the potential sources of heterogeneity using subgroup and meta-regression analysis.Ethics and disseminationThis study will use published data, so ethical approval is not required. The findings will be disseminated by publication in peer-reviewed journal(s).PROSPERO registration numberCRD42021257511.
Interventions to support the mental health and well-being of front-line healthcare workers in hospitals during pandemics: an evidence review and synthesis
Authors: Robins-Browne Kate , Lewis Matthew , Burchill Luke James , Gilbert Cecily , Johnson Caroline , O'Donnell Meaghan , Kotevski Aneta , Poonian Jasmine , Palmer Victoria J 
Published: November 2022

ObjectivePandemics negatively impact healthcare workers’ (HCW’s) mental health and well-being causing additional feelings of anxiety, depression, moral distress and post-traumatic stress. A comprehensive review and evidence synthesis of HCW’s mental health and well-being interventions through pandemics reporting mental health outcomes was conducted addressing two questions: (1) What mental health support interventions have been reported in recent pandemics, and have they been effective in improving the mental health and well-being of HCWs? (2) Have any mobile apps been designed and implemented to support HCWs’ mental health and well-being during pandemics?DesignA narrative evidence synthesis was conducted using Cochrane criteria for synthesising and presenting findings when systematic review and pooling data for statistical analysis are not suitable due to the heterogeneity of the studies.Data sourcesEvidence summary resources, bibliographic databases, grey literature sources, clinical trial registries and protocol registries were searched.Eligibility criteriaSubject heading terms and keywords covering three key concepts were searched: SARS-CoV-2 coronavirus (or similar infectious diseases) epidemics, health workforce and mental health support interventions. Searches were limited to English-language items published from 1 January 2000 to 14 June 2022. No publication-type limit was used.Data extraction and synthesisTwo authors determined eligibility and extracted data from identified manuscripts. Data was synthesised into tables and refined by coauthors.Results2694 studies were identified and 27 papers were included. Interventions were directed at individuals and/or organisations and most were COVID-19 focused. Interventions had some positive impacts on HCW’s mental health and well-being, but variable study quality, low sample sizes and lack of control conditions were limitations. Two mobile apps were identified with mixed outcomes.ConclusionHCW interventions were rapidly designed and implemented with few comprehensively described or evaluated. Tailored interventions that respond to HCWs’ needs using experience co-design for mental health and well-being are required with process and outcome evaluation.
Discrete choice experiment to investigate preferences for psychological intervention in cardiac rehabilitation
Authors: Shields Gemma E , Wells Adrian , Wright Stuart , Vass Caroline M , Doherty Patrick Joseph , Capobianco Lora , Davies Linda M 
Published: November 2022

ObjectiveCardiac rehabilitation (CR) is offered to people who recently experienced a cardiac event, and often comprises of exercise, education and psychological care. This stated preference study aimed to investigate preferences for attributes of a psychological therapy intervention in CR.MethodsA discrete choice experiment (DCE) was conducted and recruited a general population sample and a trial sample. DCE attributes included the modality (group or individual), healthcare professional providing care, information provided prior to therapy, location and the cost to the National Health Service (NHS). Participants were asked to choose between two hypothetical designs of therapy, with a separate opt-out included. A mixed logit model was used to analyse preferences. Cost to the NHS was used to estimate willingness to pay (WTP) for aspects of the intervention design.ResultsThree hundred and four participants completed the DCE (general public sample (n=262, mean age 47, 48% female) and trial sample (n=42, mean age 66, 45% female)). A preference for receiving psychological therapy was demonstrated by both samples (general population WTP £1081; 95% CI £957 to £1206). The general population appeared to favour individual therapy (WTP £213; 95% CI £160 to £266), delivered by a CR professional (WTP £48; 9% % CI £4 to £93) and with a lower cost (β=−0.002; p<0.001). Participants preferred to avoid options where no information was received prior to starting therapy (WTP −£106; 95% CI −£153 to −£59). Results for the location attribute were variable and challenging to interpret.ConclusionsThe study demonstrates a preference for psychological therapy as part of a programme of CR, as participants were more likely to opt-in to therapy. Results indicate that some aspects of the delivery which may be important to participants can be tailored to design a psychological therapy. Preference heterogeneity is an issue which may prevent a ‘one-size-fits-all’ approach to psychological therapy in CR.
Longitudinal transkingdom gut microbial approach towards decompensation in outpatients with cirrhosis
Authors: Bajaj Jasmohan S , Peña-Rodriguez Marcela , La Reau Alex , Phillips Wendy , Fuchs Michael , Davis Brian C , Sterling Richard K , Sikaroodi Masoumeh , Fagan Andrew , Shamsaddini Amirhossein , Henseler Zachariah , Ward Tonya , Puri Puneet , Lee Hannah , Gillevet Patrick M 
Published: November 2022

ObjectiveFirst decompensation development is a critical milestone that needs to be predicted. Transkingdom gut microbial interactions, including archaeal methanogens, may be important targets and predictors but a longitudinal approach is needed.DesignCirrhosis outpatients who provided stool twice were included. Group 1: compensated, group 2: 1 decompensation (decomp), group 3: >1 decompensationwere followed and divided into those who remained stable or decompensated. Bacteria, viral and archaeal presence, α/β diversity and taxa changes over time adjusted for clinical variables were analysed. Correlation networks between kingdoms were analysed.Results157 outpatients (72 group 1, 33 group 2 and 52 group 3) were followed and 28%–47% developed outcomes. Baseline between those who remained stable/developed outcome: While no α/β diversity differences were seen, commensals were lower and pathobionts were higher in those who decompensated. After decompensation: those experiencing their first decompensation showed greater decrease in α/β-diversity, bacterial change (↑Lactobacillusspp,Streptococcus parasanguinisand ↓beneficial LachnospiraceaeandEubacterium hallii) and viral change (↑Siphoviridae, ↓ Myoviridae) versus those with further decompensation. Archaea: 19% hadMethanobacter brevii, which wassimilar between/within groups. Correlation networks: Baseline archaeal-viral-bacterial networks were denser and more homogeneous in those who decompensated versus the rest. Archaea-bacterial correlations collapsed post first decompensation.Lactobacillusphage Lc Nu and C2-like viruses were negatively linked with beneficial bacteria.ConclusionIn this longitudinal study of cirrhosis outpatients, the greatest transkingdom gut microbial changes were seen in those reaching the first decompensation, compared with subsequent decompensating events. A transkingdom approach may refine prediction and provide therapeutic targets to prevent cirrhosis progression.
Changes in platelet function and coagulation after transcatheter aortic valve implantation evaluated with thromboelastography
Authors: Harada Mae , Sajima Takeyuki , Onimaru Taichi , Honjo Takahiro , Hioki Hirofumi , Watanabe Yusuke , Sawamura Shigehito 
Published: November 2022

IntroductionThe possibility of hypercoagulability during the perioperative period of transcatheter aortic valve implantation (TAVI) has been noted; however, there is still a controversy regarding the appropriate perioperative antithrombotic therapy. The study investigated coagulation and platelet functions during the TAVI perioperative period using thromboelastography (TEG) 6s platelet mapping.MethodsA prospective observational study was conducted on 25 patients undergoing TAVI. TEG platelet mapping was performed at three time points: on admission to the operating room (before heparinisation), on postoperative day (POD) 1 and on POD 3. Perioperative changes observed included: maximum clot strength (MAHKH), clot strength without platelet function (MAActF), time to initiation of clots formation by coagulation factors (RHKH) and platelet function (Gp). Gpis activated by thrombin, and not affected by antiplatelet agents. It is calculated as [(5000×MAHKH)/(100 – MAHKH)] − [(5000×MAActF)/(100 – MAActF)]. Finally, MAADP/AAand GADP/AA, which reflect clot strength and platelet aggregation mediated by ADP/thromboxane A2receptors, respectively, were also examined using the same method as for Gp.ResultsMAHKHcontinued to decrease until POD 3, indicating antithrombotic change after TAVI. Gpcontinuously decreased for 3 days after TAVI, while MAActFincreased significantly on POD 3. Furthermore, RHKHshortened on POD 1 and POD 3, suggesting increased coagulation capacity after TAVI. Finally, GADPin clopidogrel-naive patients was reduced for 3 days after TAVI, while GAAin aspirin-naive patients showed no significant change perioperatively.ConclusionsIn this study involving TEG platelet mapping, coagulation capacity increased while platelet function decreased, resulting in antithrombotic change for 3 days after TAVI. The ADP receptor system may be implicated in the decreased platelet function. These results may be useful for considering optimal perioperative antithrombotic therapy in TAVI.
CPT-even electrodynamics in a multidimensional torus: Casimir effect at finite temperature
Authors: Moreira R. P. M. , Petronilo G. X. A. , Santana A. E. , Amorim R. G. G. , Belich H. 
Published: November 2022

AbstractThe energy–momentum tensor for the electromagnetism with Lorentz breaking even term of the Standard Model Extended (SME) photon sector confined in a hyper torus is determined. A generalized partition function method is used, following in parallel the thermofield dynamics formalism written in N-dimensional toroidal manifold. After considering general aspects of the SME photon sector in a toroidal manifold, the influence of the isotropic CPT-even electromagnetic sector of the SME is analysed. The approach is then applied to the Casimir effect at finite temperature, corresponding to a topology $$(S^{1})^{r}\times R^{N-r}$$

(

S
1

)

r

×

R

N
-
r

, where N is the dimension of the Minkowski space-time, and r is the number of compactified dimensions.influence of the isotropic CPT-even electromagnetic sector of the SME is analysed.
Geometric Proca with matter in metric-Palatini gravity
Authors: Demir Durmuş , Puliçe Beyhan 
Published: November 2022

AbstractIn the present work, we study linear, torsion-free metric-Palatini gravity, extended by the quadratics of the antisymmetric part of the Ricci tensor and extended also by the presence of the affine connection in the matter sector. We show that this extended metric-Palatini gravity reduces dynamically to the general relativity plus a geometrical massive vector field corresponding to non-metricity of the connection. We also show that this geometric Proca field couples to fermions universally. We derive static, spherically symmetric field equations of this Einstein-geometric Proca theory. We study possibility of black hole solutions by taking into account the presence of a dust distribution that couples to the geometric Proca. Our analytical and numerical analyses show that the presence of this dust worsens the possibility of horizon formation. We briefly discuss possible roles of this universally-coupled geometric Proca in the astrophysical and collider processes.
Dynamical conductivity of disordered quantum chains
Authors: Takayoshi Shintaro , Giamarchi Thierry 
Published: November 2022

Abstract
We study the transport properties of a one-dimensional quantum system with disorder. We numerically compute the frequency dependence of the conductivity of a fermionic chain with nearest-neighbor interaction and a random chemical potential by using the Chebyshev matrix product state (CheMPS) method. As a benchmark, we investigate the noninteracting case first. Comparison with exact diagonalization and analytical solutions demonstrates that the results of CheMPS are reliable over a wide range of frequencies. We then calculate the dynamical conductivity spectra of the interacting system for various values of the interaction and disorder strengths. In the high-frequency regime, the conductivity decays as a power law, with an interaction-dependent exponent. This behavior is qualitatively consistent with the bosonized field theory predictions, although the numerical evaluation of the exponent shows deviations from the analytically expected values. We also compute the characteristic pinning frequency at which a peak in the conductivity appears. We confirm that it is directly related to the inverse of the localization length, even in the interacting case. We demonstrate that the localization length follows a power law of the disorder strength with an exponent dependent on the interaction, and find good quantitative agreement with the field theory predictions. In the low-frequency regime, we find a behavior consistent with the one of the noninteracting system $$\omega ^{2}(\ln \omega )^{2}$$

ω
2

(
ln
ω
)

2

independently of the interaction. We discuss the consequences of our finding for experiments in cold atomic gases.

Graphical abstract
Do You Need a Distributed Ledger Technology Interoperability Solution?
Authors: Belchior Rafael , Riley Luke , Hardjono Thomas , Vasconcelos André , Correia Miguel 
Published: November 2022

Entrepreneurs, enterprises, and governments are using distributed ledger technology (DLT) as a component of complex information systems, and therefore interoperability capabilities are required. Interoperating DLTs enable network effects and synergies, and similarly to the rise of the Internet, it unlocks the full potential of the technology. However, due to the novelty of the area, interoperability mechanisms (IMs) are still not well understood, as interoperability is studied in silos. Consequently, choosing the proper IM for a use case is challenging.
Our article has three contributions: first, we systematically study the research area of DLT interoperability by dissecting and analyzing previous work. We study the logical separation of interoperability layers, how a DLT can connect to others (connection mode), the object of interoperation (interoperation mode), and propose a new categorization for IMs. Second, we propose the first interoperability assessment for DLTs that systematically evaluates the interoperability degree of an IM. This framework allows comparing the potentiality, compatibility, and performance among solutions.
Finally, we propose two decision models to assist in choosing an IM, considering different requirements. The first decision model assists in choosing the infrastructure of an IM, while the second decision model assists in choosing its functionality.