bluuebunny/crossref_metadata_2025_split huggingface dataset:
Harga Tunai, Kualitas produk, Citra merk dan Iklan Terhadap keputusan Pembelian Smartphone Samsung di wilayah Jabodetabek
Authors: Mulyadhi Mulyadhi , Buzaman Hamidi Adi , Anis Billy Josef 
Published: August 2022

Penelitian bermaksud menganalisis harga tunai, kualitas produk, citra merk dan iklan terhadap keputusan pembelian smartphone samsung. Pengumpulan data dengan pengisian kuesioner yang didistribusikan kepada pengguna smartphone samsung di Jabodetabek selama rentang waktu bulan Juni 2022 dan diperoleh 80 responden. Analisis data struktural diolah menggunakan WarpPLS. Hasil penelitian menunjukkan harga tunai dan kualitas produk tidak mempengaruhi keputusan konsumen dalam pembelian. Citra merk dan iklan berpengaruh secara positif terhadap keputusan pembelian.
This study intends to analyze cash prices, product quality, brand image and advertising on samsung smartphone purchasing decisions. Data collection by filling out a questionnaire distributed to Samsung smartphone users in Jabodetabek during the period of June 2022 and obtained by 80 respondents. Structural data analysis was processed using WarpPLS. The results showed that cash prices and product quality did not affect consumer decisions in purchasing. Brand image and advertising positively affect purchasing decisions.
Penggolongan Generasi sebagai Pemoderasi Lingkungan Kerja, Kepemimpinan dan Beban Kerja terhadap Loyalitas Karyawan
Authors: Saepudin Denden , Sugito Sugito , Jayadi Jayadi 
Published: August 2022

Penelitian ini bertujuan mengetahui penggolongan generasi sebagai pemoderasi lingkungan kerja, kepemimpinan dan beban kerja terhadap loyalitas karyawan. Penelitian ini menggunakan metode survei dengan membagikan kuesioner kepada 80 orang generasi X dan generasi Y yang sudah bekerja. Pengujian instrument yang terdiri uji validitas sedangkan untuk uji reliabilitas menggunakan metode analisis Cronbach alpha. Dan untuk pengujian hipotesis menggunakan bootsrapp dan alat analisis yang digunakan dalam penelitian ini adalah program PLS versi 3.3. Hasil yang didapat adalah penggolongan generasi sebagai pemoderasi lingkungan kerja berpengaruh signifikan terhadap loyalitas karyawan. Penggolongan generasi sebagai pemoderasi kepemimpinan terhadap loyalitas karyawan juga memberikan pengaruh yang siginfikan. Akan tetapi penggolongan generasi sebagai pemoderasi beban kerja tidak berpengaruh signifikan terhadap loyalitas karyawan.
This study aims to determine the classification of generations as moderating work environment, leadership and workload on employee loyalty. This study uses a survey method by distributing questionnaires to generation X and generation Y who have worked by providing demographics such as gender, education and workplace organization. The number of respondents is 80 people. Testing the instrument consisting of a validity test while the reliability test uses the Cronbach alpha analysis method. And for hypothesis testing using bootstrap and the analytical tool used in this study is the PLS version 3.3 program. The results obtained from this study are generational classification as moderating work environment has a significant effect on employee loyalty. Generational classification as moderating leadership on employee loyalty also has a significant effect. However, the classification of generations as moderating workloads has no significant effect on employee loyalty
What are the Composition and Power of the Jet in Cyg X-1?
Authors: Zdziarski Andrzej A. , Egron Elise 
Published: August 2022

Abstract
We calculate the electron–positron pair production rate at the base of the jet of Cyg X-1 by collisions of photons from its hot accretion flow using the measurement of its average soft gamma-ray spectra by the Compton Gamma Ray Observatory and INTEGRAL satellites. We have found that this rate approximately equals the flow rate of the leptons emitting the observed synchrotron radio-to-IR spectrum of the jet, calculated using an extended jet model following that of Blandford & Königl. This coincidence shows the jet composition is likely to be pair dominated. The same coincidences were found before in the microquasar MAXI J1820+070 and in the radio galaxy 3C 120, which shows that the considered mechanism can be universal for at least some classes of relativistic jets. Furthermore, we recalculate the jet power of Cyg X-1. The presence of pairs can strongly reduce the power in the bulk motion of ions, which then limits the parameter space at which the jet can power the ∼5 pc nebular structure present in its vicinity.
Formation of Magnetically Truncated Accretion Disks in 3D Radiation-transport Two-temperature GRMHD Simulations
Authors: Liska M. T. P. , Musoke G. , Tchekhovskoy A. , Porth O. , Beloborodov A. M. 
Published: August 2022

Abstract
Multiwavelength observations suggest that the accretion disk in the hard and intermediate states of X-ray binaries (XRBs) and active galactic nucleus transitions from a cold, thin disk at large distances into a hot, thick flow close to the black hole (BH). However, the formation, structure, and dynamics of such truncated disks are poorly constrained due to the complexity of the thermodynamic, magnetic, and radiative processes involved. We present the first radiation-transport two-temperature general relativistic magnetohydrodynamic (GRMHD) simulations of truncated disks radiating at ∼35% of the Eddington luminosity with and without large-scale poloidal magnetic flux. We demonstrate that when a geometrically thin accretion disk is threaded by large-scale net poloidal magnetic flux, it self-consistently transitions at small radii into a two-phase medium of cold gas clumps floating through a hot, magnetically dominated corona. This transition occurs at a well-defined truncation radius determined by the distance out to which the disk is saturated with magnetic flux. The average ion and electron temperatures in the semiopaque corona reach, respectively, T

i
≳ 1010 K and T

e
≳ 5 × 108 K. The system produces radiation, powerful collimated jets, and broader winds at the total energy efficiency exceeding 90%, the highest ever energy extraction efficiency from a spinning BH by a radiatively efficient flow in a GRMHD simulation. This is consistent with jetted ejections observed during XRB outbursts. The two-phase medium may naturally lead to broadened iron line emission observed in the hard state.
New Constraints on the Volatile Deposit in Mercury’s North Polar Crater, Prokofiev
Authors: Barker Michael K. , Chabot Nancy L. , Mazarico Erwan , Siegler Matthew A. , Martinez-Camacho Jose M. , Hamill Colin D. , Bertone Stefano 
Published: August 2022

Abstract
We present new high-resolution topographic, illumination, and thermal models of Mercury’s 112 km diameter north polar crater, Prokofiev. The new models confirm previous results that water ice is stable at the surface within the permanently shadowed regions (PSRs) of Prokofiev for geologic timescales. The largest radar-bright region in Prokofiev is confirmed to extend up to several kilometers past the boundary of its PSR, making it unique on Mercury for hosting a significant radar-bright area outside a PSR. The near-infrared normal albedo distribution of Prokofiev’s PSR suggests the presence of a darkening agent rather than pure surface ice. Linear mixture models predict at least roughly half of the surface area to be covered with this dark material. Using improved altimetry in this crater, we place an upper limit of 26 m on its ice deposit thickness. The 1 km baseline topographic slope and roughness of the radar-bright deposit are lower than the non-radar-bright floor, although the difference is not statistically significant when compared to the non-radar-bright floor’s natural topographic variations. These results place new constraints on the nature of Prokofiev’s volatile deposit that will inform future missions, such as BepiColombo.
The Effectiveness of Curcumin on Transforming Growth Factor-β and the Proportion of Liver Fibrosis in Deutschland Denken Yoken Mice with Common Bile Duct Ligation
Authors: Amanda Prathita , Prabowo Erik , Muniroh Muflihatul , Rozy Abdul Mughni , Susilaningsih Neni 
Published: August 2022

ABSTRACT

Background/Aims: Curcumin has been associated to reduce liver fibrosis damage. For this purpose, TGF-b and proportion of liver fibrosis were assessed.
Methods: A total of 75 male DDY mice models were included in 15 treatment groups. The treatment and positive control groups were given curcumin, UDCA, and a combination of curcumin and UDCA. Common bile duct ligation was performed 7 days after the treatment following the histopathology examination of the liver on days 7,14, and 21.
Results: Curcumin decreased the expression of TGF-β compared to the negative control (p<.001). It also reduces the expression of TGF-β compared to UDCA but without any significant differences (p = 0,755; p = 0,701; p=0,677), and combination group (p=0,204; p=0,549; p=0,276). Curcumin also reduces the proportion of liver fibrosis compared to UDCA but without any significant differences (p=0,825; p=0,199; p=0,915), and combination group (p=0,859, p=0,328, p=0,076).
Conclusions: Curcumin has the ability on reducing the expression of TGF-β and the proportion of liver fibrosis. It can be suggested that curcumin almost has the same effectiveness as UDCA.
Keywords: Curcumin, ursodeoxycholic acid, common bile duct ligation, liver fibrosis
A comparative study of combination treatments in metastatic 4t1 cells: everolimus and 5- fluorouracil versus lithium chloride and 5-fluorouracil
Authors: Altememy Dhiya , Mohammadi Arvejeh Pooria , Amini Chermahini Fatemeh , Alizadeh Akram , Mazarei Madineh , Khosravian Pegah 
Published: August 2022

Background: Combination therapy has been one of the most pioneering and strategic approaches implemented for malignancy treatment, which can intentionally influence multiple signaling pathways involved in cancer growth and progression. In the present study, the effects of 5-fluorouracil (5FU) in combination with everolimus (EVE) or lithium chloride (LiCl) were evaluated in 4T1 metastatic breast cancer cells and compared to control and each other.
Methods and results: The resazurin assay, CompuSyn, flow cytometry, and real-time PCR were used to investigate cell proliferation, drug synergism, apoptosis, and gene expression. In comparison to the ternary combination of the drugs, the findings showed that cytotoxicity (p-value &lt; 0.0001) and apoptosis (p-value &lt; 0.0001) of two-by-two combinations increased dramatically as a consequence of the extreme synergy between 5FU and EVE or LiCl. Moreover, the hypoxia­inducible transcription factor 1-alpha (HIF-1α) and the vascular endothelial growth factor (VEGF) downregulated considerably compared to control (p-value &lt; 0.0001) by combination therapies of EVE-5FU and 5FU-LiCl; however, only VEGF displayed significant downregulation in comparison to single therapies.
Conclusion: The findings showed that the combination of 5FU-LiCl increased cell cytotoxicity and apoptosis significantly more than EVE-5FU but suggests a clinical potential for both to treat metastatic breast cancer encouraging validation of these results in pre-clinical models.
The Power of a Story: Enhancing Students' Empathy for Transgender Pregnant Men
Authors: McMillian-Bohler Jacquelyn , Gedzyk-Neiman Stephanie , Hepler Bonnie , May Jennifer T. , Koch Amie 
Published: August 2022

Background:
Transgender individuals continue to face stigma and discrimination within the health care system. Sharing the lived experience of transgender pregnant men can increase awareness, understanding, and empathy for this underrepresented population.

Method:
A transgender man (and advocate) shared his pregnancy experiences with students enrolled in a maternity course. Students completed pre- and postpresentation surveys on their perceptions of working with transgender patients and the importance of providing transgender-affirming care.

Results:
Students reported the speaker's presentation increased their awareness of the experience of transgender patients. Many students reported increased interest and desire to provide trans-affirming care.

Conclusion:

Nursing faculty can provide opportunities for students to meet and speak with transgender patients as a strategy to increase empathy and reduce discrimination toward transgender patients in health care.

[
J Nurs Educ
. 2022;61(8):489–492.]
Carotid Artery Blood Flow Changes Associated with Head Positioning in Patients Undergoing Thyroidectomy
Authors: Asokan Abhilash , Sreejit Melveetil S. 
Published: August 2022

Background and Aims:
There are possibilities of insufficiency in blood flow through carotid arteries during head positioning in thyroid surgeries under general anesthesia which is usually compensated by collateral circulation in normal conditions. This compensation may be hampered in patients with congenital abnormalities or diseases such as atherosclerosis. We aimed to elucidate the changes in common carotid artery blood flow related to head positioning during thyroid surgery by Doppler examination.

Methods:
In this observational prospective study, Doppler examination of both common carotid arteries including arterial diameter, peak systolic velocity, average velocity, and blood flow volume of forty patients who had undergone elective thyroidectomy under endotracheal anesthesia was done. Three sets of data (baseline, after induction, and after surgery) were collected and analyzed.

Results:
There was a significant reduction in the diameter (P = 0.002) and the blood flow (P = 0.0001) in both carotid arteries and an increase in peak and mean velocity which was more pronounced immediately after head positioning and persisted till the end of the procedure. There was no correlation between the hemodynamic parameters with the carotid artery diameter, blood flow, and velocity.

Conclusions:
The head-and-neck positioning during thyroidectomy surgery reduces the blood flow through the carotid arteries which continued till the end of the procedure.
Levobupivacaine versus Levobupivacaine Plus Dexmedetomidine in Transversus Abdominis Plane Block in Patients Undergoing Abdominal Aortic Surgery
Authors: Abdallah Maha Younis Youssef , Abdallah Mohamed Younes Yousef 
Published: August 2022

Background:
Severe postoperative pain is a major dilemma for patients undergoing abdominal aortic surgery. Transversus abdominis plane (TAP) block has been described a successful pain management technique after major abdominal surgery. Dexmedetomidine was proved to enhance the analgesic action of local anesthetics.

Aim:
This study was aimed to assess the impact of adding dexmedetomidine to levobupivacaine during TAP block in patients undergoing abdominal aortic operations.

Patients and Methods:
We included 114 patients in this prospective trial, and they were enrolled into two groups; the L group received levobupivacaine only, and the LD group received levobupivacaine plus dexmedetomidine. The block was performed before anesthetic induction. Postoperative pain score was our main outcome.

Statistical Analysis:
The collected data were tabulated and analyzed through the SPSS software program IBM's Statistical Package for the Social Sciences (SPSS) statistics for Windows (version 25, 2017) (IBM Corporation, Armonk, NY, USA). The categorical data were expressed as numbers and percentages and then compared using the Chi-square test. The continuous data were expressed as mean and standard deviation if normally distributed, or median and range if abnormally distributed. The former data were compared through the one-way ANOVA, while the latter were compared through the Kruskal–Wallis test. Any P < 0.05 was considered statistically significant.

Results:
Group LD showed significantly earlier sensory blocks compared to the other group. Postoperative pain scores were comparable between the two groups for the initial 4 h following the surgery. Adjuvant dexmedetomidine was associated with better pain scores for the subsequent 12 h compared to Group L. The duration till the first analgesic request showed a significant increase in the LD group (13.3 vs. 11.09 h in Group L). In addition, the same group showed a significant decline in their opioid consumption after the operation (48.95 μg vs. 72.63 μg in the other group). Postoperative nausea and vomiting were significantly increased in Group L.

Conclusion:
Adjuvant dexmedetomidine has a significant beneficial impact on postoperative analgesic profile. Its use as an adjuvant to peripheral and neuraxial nerve blocks should be recommended in pain management practice.
Enamel Surface Roughness Evaluation After Bracket Debonding
Authors: Chandrasekharan Deepak , Sourabh Chandan , Deenadayalan  , Praveen Katepogu 
Published: August 2022

Introduction:
After fixed orthodontic treatment, following bracket removal, the debonding procedure should lead to restitutio ad integrum of the enamel or, at least, restore the enamel surface as closely as possible to its pretreatment condition. Adhesion of brackets in orthodontics is that they should be strong enough to prevent failure during all treatment but also low enough, so that enamel damage would be minimal during bracket removal after treatment.

Material and Methods:
A total of 60 premolars were collected and stored in distilled water. The extracted teeth were divided into two groups of 30 each, group A was to be bonded with self-cure adhesive while group B light cure adhesive was to be used. A standardised protocol was followed for adhering the brackets to the tooth surfaces. All the teeth were bonded with metal brackets (3M Unitek, Gemini Twin Brackets 0.022 slot). In group A, bonding adhesive (3M Unitek self cure adhesive primer) was applied. In group B, the bonding adhesive (3M Unitek light cure adhesive primer) was photopolymerized for 10 seconds after application.

Results:
Surface roughness of enamel as assessed by profilometry shows that light cure adhesive creates more roughness as compared to self cure adhesive. To conclude, self cure adhesive is clinically better than light cure adhesive.

Discussion:
In the present study enamel surface roughness were compared after debonding. Enamel surface roughness after bracket debonding depends on a host of factors, which include – brackets, adhesive used and method of remnant removal.
Root Canal Morphology of Primary Molars – A Cone Beam Computed Tomography (CBCT) Study
Authors: Dhillon Jatinder K. , Ghosh Sujoy , Mathur Vijay P. 
Published: August 2022

Objectives:
To evaluate the root and canal morphology of primary maxillary and mandibular molars in an Indian population using cone-beam computed tomography (CBCT).

Methods:
A retrospective cross-sectional study was performed, where CBCT scans of children less than 10 years of age taken for valid diagnostic purposes previously were considered and images were analyzed. The number of roots, root canals, and variations in morphology were recorded. Left–right symmetry was also noted.

Results:
A total of 433 deciduous maxillary and mandibular primary molars were studied. It was observed that two separate roots with three separate canals were common in primary mandibular first molars, whereas two separate roots with two canals in each root were common in mandibular second primary molars. In primary maxillary molars, three separate roots with one canal each were the most common. Maxillary first molars (17.21%) and 17.35% second molars had fused distobuccal and palatal roots. It was observed that primary maxillary molars showed more left–right symmetry (86.7% in first molars and 82.7% in second molars) compared to primary mandibular molars (54.05% in first molars and 68% in second molars).

Conclusions:
It was concluded that in both primary maxillary first and second molars, three separate roots, a mesiobuccal root, a distobuccal root, and a palatal root with one canal in each root, were the most common. Two separate roots with three separate canals were the most common in primary mandibular first molars, whereas two separate roots with two canals each in both roots were more common in mandibular second primary molars.
Evaluation of the Effect of Nonsurgical Periodontal Therapy on Malondialdehyde and 8-Hydroxy Deoxyguanosine Levels in Chronic Periodontitis
Authors: Gautam Anju , Mittal Neelam , Mishra Surendra Pratap , Singh Tej Bali , Chandra Akhilesh 
Published: August 2022

Background:
Reactive oxygen species released on stimulation by periodontal pathogens cause oxidation of biomolecules and play significant role in periodontal disease pathogenesis.

Aim:
This study aimed to evaluate the levels of oxidative by-products malondialdehyde (MDA) and 8-hydroxy deoxyguanosine (8-OHdG) as biomarkers in chronic periodontitis patients compared to healthy as well as before and after nonsurgical periodontal therapy. The correlation between biomarkers and clinical attachment level was also evaluated.

Settings and Design:
A total of 112 subjects were included in this study. The subjects were divided into two groups (Group I included 56 healthy subjects and Group II constituted 56 chronic periodontitis patients) on the basis of clinical periodontal parameters.

Materials and Methods:
Group I subjects received no treatment and were evaluated once only for clinical and oxidative stress biomarker parameters. Nonsurgical periodontal therapy was carried out in Group II patients and they were evaluated at baseline and 3 months after therapy.

Results:
Both salivary and serum levels of MDA and 8-OHdG were found to be increased in chronic periodontitis patients as compared to healthy subjects. After nonsurgical periodontal therapy, the levels of MDA and 8-OHdG significantly reduced. Linear correlation between clinical attachment level and oxidative stress parameters was found to be positive and highly significant.

Conclusion:
It can be concluded that periodontal therapy is effective in improving the oxidative stress condition.
Degradação ambiental e qualidade da água de rios urbanos: o caso dos corpos d'água de Paraíso do Tocantins, TO, Brasil
Authors: Almeida Rejane Freitas Benevides , Cardoso Maria Marielly Araújo 
Published: August 2022

<span>O presente trabalho teve como objetivo realizar o diagnóstico ambiental dos corpos d’água que cortam a área urbana do município de Paraíso do Tocantins, identificando as principais causas da degradação da qualidade ambiental e suas consequências para a qualidade da água. Para tanto, inicialmente, foi realizado um diagnóstico ambiental dos principais cursos d’água existentes na cidade (córregos Pernada e Buriti), por meio de visitas a campo. Posteriormente, foram selecionados pontos para o monitoramento da qualidade da água ao longo de cada canal de drenagem, sendo: ponto 1 – a montante da área urbana; ponto 2 – no início da área urbana; ponto 3 – no meio da área urbana; e ponto 4 – a jusante da área urbana, para os quais foram realizadas análises físicas, químicas e microbiológicas, conforme </span><span>Standard Methods for the Examination of Water and Wasterwater. Os resultados indicaram alterações significativas sobre a qualidade da água ao longo dos corpos d’água avaliados, sendo verificados padrões de qualidade da água em desacordo com a legislação para os </span><span>parâmetros nitrito, fósforo total, oxigênio dissolvido e coliformes termotolerantes<span>. </span></span><span>Desse modo, a realização deste trabalho permitiu uma análise mais abrangente dos efeitos do uso e da ocupação do solo sobre a qualidade ambiental dos corpos d’água urbanos do município, sendo bastante útil para fomentar as discussões e o planejamento de políticas municipais voltadas à gestão do uso do solo urbano.</span>