bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unique Chemistry and Structure of Pyrolyzed Bovine Bone for Enhanced Aqueous Metals Adsorption
Authors: Muretta Julie E. , Prieto-Centurion Dario , LaDouceur Richard , Kirtley John D. 
Published: August 2022

AbstractBone waste is a problematic slaughterhouse waste typically disposed of in landfills. The pyrolyzed product of this waste shows strong potential in mine and industrial waste water remediation and work is needed to identify chemical and structural parameters which drive performance. Diffuse Reflectance Fourier Transform Spectroscopy (DRIFTS) was used to probe carbonate (CO32−), phosphate (PO43−) and hydroxyl (OH−) environments of mineral phases and functional group chemistry in carbonaceous phase, revealing a potentially synergistic functionality between the two in bone char. CO32− and water substitutions in the mineral lattice were found to persist after pyrolysis to 750 °C, and more soluble non-apatite calcium phosphate phases were observed using second derivative analysis of the v3 PO43− band. Nitrogen-rich functional groups were found in the carbonaceous phase which are associated with complexation of aqueous metals, and ordered aromatic clusters identified by Raman spectroscopy indicate a porous carbon skeletal structure to promote metals adsorption and complexation. These results point to unique chemical and structural features of bone char which are not easily replicated by synthetic carbonated apatite or activated carbon and which contribute to the excellent aqueous metals removal power of bone char.
Graphical Abstract
Virtual landscape-scale restoration of altered channels helps us understand the extent of impacts to guide future ecosystem management
Authors: Paul Siddhartho Shekhar , Hasselquist Eliza Maher , Jarefjäll Amanda , Ågren Anneli M. 
Published: August 2022

AbstractHuman modification of hydrological connectivity of landscapes has had significant consequences on ecosystem functioning. Artificial drainage practices have fundamentally altered northern landscapes, yet these man made channels are rarely considered in ecosystem management. To better understand the effects of drainage ditches, we conducted a landscape-scale analysis across eleven selected study regions in Sweden. We implemented a unique approach by backfilling ditches in the current digital elevation model to recreate the prehistoric landscape, thus quantifying and characterizing the channel networks of prehistoric (natural) and current (drained) landscapes. Our analysis detected that 58% of the prehistoric natural channels had been converted to ditches. Even more striking was that the average channel density increased from 1.33 km km−2 in the prehistoric landscape to 4.66 km km−2 in the current landscape, indicating the extent of ditching activities in the northern regions. These results highlight that man-made ditches should be accurately mapped across northern landscapes to enable more informed decisions in ecosystem management.
A simplified low volume colorimetric assay for rapid comparison of cyanogenic glycoside production between barley genotypes
Authors: Xue Shiming , Zantinge Jennifer L. , Holtz Michael D. , Juskiw Patricia 
Published: August 2022

AbstractEthyl carbamate (EC), a genotoxic and carcinogenic compound, is an undesirable trace component in spirits and whisky. The precursor of EC produced from barley (Hordeum vulgareL.) malt is primarily a cyanogenic glycosidic nitrile (GN) known as epiheterodendrin (EPH). EPH production is genetically controlled in barley, low or non-GN varieties exist and EPH production can be controlled by using low or non-GN barley varieties for malt production. Here, we report on a rapid and inexpensive colorimetric assay modified from Cook and Oliver (in: European Brewery Convention (eds) Proceedings of the 23rd Congress, Lisbon. European Brewery Convention, Zoeterwoude, Netherlands, 1991). The new low-volume, high-throughput, semi-quantitative test method can be used for the selection of low or non-GN breeding lines through samples of acrospires. This method is based on the detection of cyanide by the reaction with chloramine-T followed by the addition of the reagent (pyridine-barbituric acid) to form a soluble violet-blue product measured at 590 nm. Absorbance measurements and the visual color are used to estimate the presence of EPH production in acrospires. In this report, the level of EPH production was compared among some commercial European non-GN lines, Canadian malt varieties and advanced barley breeding lines.
Cluster of differentiation antigens: essential roles in the identification of teleost fish T lymphocytes
Authors: Tian Hong-fei , Xing Jing , Tang Xiao-qian , Chi Heng , Sheng Xiu-zhen , Zhan Wen-bin 
Published: August 2022

AbstractCluster of differentiation (CD) antigens are cell surface molecules expressed on leukocytes and other cells associated with the immune system. Antibodies that react with CD antigens are known to be one of the most essential tools for identifying leukocyte subpopulations. T lymphocytes, as an important population of leukocytes, play essential roles in the adaptive immune system. Many of the CD antigens expressed on T lymphocytes are used as surface markers for T lymphocyte classification, including CD3, CD4 and CD8 molecules. In this review, we summarize the recent advances in the identification of CD molecules on T lymphocytes in teleosts, with emphasis on the functions of CD markers in the classification of T lymphocyte subsets. We notice that genes encoding CD3, co-receptors CD4 and CD8 have been cloned in several fish species and antibodies have been developed to study protein expression in morphological and functional contexts. T lymphocytes can be divided into CD4+and CD8+cells discriminated by the expression of CD4 and CD8 molecules in teleost, which are functionally similar to mammalian helper T cells (Th) and cytotoxic T cells (Tc), respectively. Further studies are still needed on the particular characteristics of teleost T cell repertoires and adaptive responses, and results will facilitate the health management and development of vaccines for fish.
The structural effect between the output module and chromophore-binding domain is a two-way street via the hairpin extension
Authors: Kurttila Moona , Etzl Stefan , Rumfeldt Jessica , Takala Heikki , Galler Nadine , Winkler Andreas , Ihalainen Janne A. 
Published: August 2022

AbstractSignal transduction typically starts with either ligand binding or cofactor activation, eventually affecting biological activities in the cell. In red light-sensing phytochromes, isomerization of the bilin chromophore results in regulation of the activity of diverse output modules. During this process, several structural elements and chemical events influence signal propagation. In our study, we have studied the full-length bacteriophytochrome fromDeinococcus radioduransas well as a previously generated optogenetic tool where the native histidine kinase output module has been replaced with an adenylate cyclase. We show that the composition of the output module influences the stability of the hairpin extension. The hairpin, often referred as the PHY tongue, is one of the central structural elements for signal transduction. It extends from a distinct domain establishing close contacts with the chromophore binding site. If the coupling between these interactions is disrupted, the dynamic range of the enzymatic regulation is reduced. Our study highlights the complex conformational properties of the hairpin extension as a bidirectional link between the chromophore-binding site and the output module, as well as functional properties of diverse output modules.
A Practice-based Account of The Truth Norm of Belief
Authors: Wei Xintong 
Published: August 2022

AbstractIt is a platitude that belief is subject to a standard of correctness: a belief is correct if and only if it is true. But not all standards of correctness are authoritative or binding. Some standards of correctness may be arbitrary, unjustified or outrightly wrong. Given this, one challenge to proponents of the truth norm of belief, is to answer what Korsgaard (1996) calls ‘the normative question’. Is the truth norm of belief authoritative or binding regarding what one ought to or may believe? If so, what grounds its authority? The aim of this paper is to offer a novel answer to the grounding challenge on a reason-based normative framework. I develop and defend a practice-based account of the truth norm, according to which, the authority of the truth norm of belief is grounded in what I call the T-practice, a justified social practice that functions to facilitate knowledge production, maintenance, and social cooperation.
Gendering Cabinet Reshuffles in France and Spain
Authors: Beckwith Karen , Franceschet Susan 
Published: August 2022

AbstractPresidents and prime ministers who form gender-parity cabinets receive positive news coverage and public praise. Cabinet reshuffles, with less attention, may offer scope to decrease the numbers of female ministers. Although research on the gendered impact of reshuffles is sparse, some studies suggest that women's presence declines during reshuffles. This article explores the gendered dynamics of reshuffles that follow initial gender-parity cabinets, asking whether the reshuffle context affects the proportions of men and women in reorganized cabinet teams. Employing a comparative case study approach, the article analyses initial gender-parity cabinets and subsequent reshuffled cabinets in France and Spain across three different presidents and prime ministers. We find that gender parity functions as a concrete floor, sustained in cabinet reshuffles, unaffected by political shocks and party system changes, and without consequence for women's appointments to high-prestige ministerships.
The appropriateness of the decision to quarantine healthcare workers exposed to a severe acute respiratory coronavirus virus 2 (SARS-CoV-2)–positive coworker based on national guidelines
Authors: Mark Eyal , Saidel-Odes Lisa , Borer Abraham , Nativ Ronit , Sterer Batya , Yarmitsky Suzana , Dreiher Jacob 
Published: August 2022

AbstractObjective:To examine the appropriateness of the decision to quarantine healthcare workers (HCWs) exposed to coronavirus disease 2019 (COVID-19).Design:Retrospective cohort study.Setting:A tertiary-care medical center in Israel.Participants:HCWs exposed to a coworker infected with severe acute respiratory coronavirus virus 2 (SARS-CoV-2).Methods:Quarantined and nonquarantined HCWs were followed for up to 1 month following exposure and their COVID-19 status was determined. The validity of the decision to quarantine was assessed.Results:In total, 2,595 HCWs exposed to 419 confirmed index cases were studied. Of the contact cases, 752 HCWs were quarantined and 1,843 HCWs were not. Of those quarantined, 36 became SARS-CoV-2 positive (4.7%). Among those who were not quarantined, only 13 (0.7%) became SARS-CoV-2 positive, which translated to a sensitivity of 73.5% and a specificity of 71.9% for the decision to quarantine (positive and negative predictive values: 4.7% and 99.3%, respectively). Controlling for confounders, the decision to quarantine the HCW by the Israeli Ministry of Health guidelines was associated with a significant risk of becoming SARS-CoV-2 positive (RR, 3.83; 95% CI, 1.98–7.36; P = .001). If a nonselective policy was used, 11,700 working days would have been lost (902 working days lost per positive case).Conclusions:An efficient and tight system of HCW contact investigations served its purpose in our hospital during the COVID-19 pandemic. This study was based on HCW reports and reported adherence to safety regulations, and these findings are relevant to the massive pandemic waves due to the SARS-CoV-2 α (alpha) variant. These Methods demonstrate an effective way of handling risk without causing damage due to arbitrary risk-control measures.
Reconstruction of cyclic Mesozoic–Cenozoic stress development in SE Germany using fault-slip and stylolite inversion
Authors: Köhler Saskia , Duschl Florian , Fazlikhani Hamed , Koehn Daniel , Stephan Tobias , Stollhofen Harald 
Published: August 2022

AbstractThe Franconian Platform of SE Germany and the underlying Permian and Triassic rocks that developed from latest Permian to Triassic time were affected by multiple compressional and extensional events that created a complex fracture, fault and stylolite network. We reconstructed the spatio-temporal variations of post-Triassic palaeostress fields in the Franconian Platform and Triassic strata using fault-slip and tectonic stylolite inversion. Our highly resolved stress inversion enables us to demonstrate a cyclic stress evolution from the stress regime of normal faulting to thrusting, strike-slip and back to normal faulting. Five main stress fields correlating with two stress cycles are determined for Late Jurassic to Cenozoic time. The first cycle consists of: (SF1) an initially NE–SW-directed horizontal extension during Late Jurassic to Early Cretaceous time; (SF2) NNE–SSW-directed horizontal compression with an early set of tectonic stylolites prior to the development of reverse and thrust faults; and (SF3) a strike-slip-dominated setting with (N)NE–(S)SW horizontal compression representing a first relaxation. The second cycle comprises (SF4) NW–SE-directed horizontal extension during Oligocene–Miocene time; and (SF5) a second strike-slip-dominated regime with WNW–ESE to NW–SE horizontal compression during the Alpine shortening, creating the youngest set of tectonic stylolites. In addition, we consider the transitional stages between thrusting and a strike-slip regime as a snapshot in the process of intraplate tectonics.
Endoparasite community of anurans from an altitudinal rainforest enclave in a Brazilian semiarid area
Authors: de Oliveira C.R. , Mascarenhas W. , Batista-Oliveira D. , de Castro Araújo K. , Ávila R.W. , Borges-Nojosa D.M. 
Published: August 2022

AbstractIn the present study, we aimed to describe the composition of endoparasites associated with anurans from an altitudinal rainforest enclave in northeastern Brazil. Additionally, we tested if microhabitat use influences endoparasite abundance and richness, as well as the hypothesis that larger frogs tend to be more parasitized. We sampled 306 individuals from 25 anuran species that were necropsied and analysed using a stereomicroscope. The total endoparasite prevalence was 79.08%, with a parasitic community consisting of 46 taxa. Overall, we found the common pattern described for Neotropical amphibians, which is the predominance of generalist and direct-cycle parasites. Twenty new host records and two possible new parasite species were found, highlighting the importance of this type of inventory. We also observed that microhabitat use was associated with a significant difference in parasite richness between groups, in which arboreal and terrestrial species, and aquatic and arboreal species contributed to these differences. Moreover, larger frogs tended to be more parasitized regarding only an interspecific view. Our results suggest that parasite richness is directly related to infection cycle and how the host exploits its habitat.
Annual incidence of substance-induced psychoses in Scandinavia from 2000 to 2016
Authors: Rognli Eline Borger , Taipale Heidi , Hjorthøj Carsten , Mittendorfer-Rutz Ellenor , Bramness Jørgen G. , Heiberg Ina H. , Niemelä Solja 
Published: August 2022

AbstractBackgroundSubstance-induced psychosis (SIP) is a serious condition and may predispose for schizophrenia. We know too little about SIP incidence over time and across countries, including substance-specific SIPs. We estimated annual incidence rate of SIP in Denmark, Norway, and Sweden according to substance, age, gender, and socioeconomic background.MethodsData were drawn from registries covering the whole adult population in the countries. Annual incidence rate per 100 000 persons of SIPs was estimated for Denmark and Sweden from 2000 to 2016 and for Norway from 2010 to 2015.ResultsThe annual incidence rate of any SIP fluctuated between 9.3 and 14.1. The most commonly occurring SIPs were those induced by alcohol, cannabis, amphetamines, and multiple substances. There was a steady decrease in the incidence rate of alcohol-induced psychosis from the first to the last year of the observation period in Denmark (from 4.9 to 1.5) and Sweden (from 4.5 to 2.2). The incidence rate of cannabis-induced psychosis increased in all countries, from 2.6 to 5.6 in Denmark, from 0.8 to 2.7 in Sweden, and from 1.8 to 3.0 in Norway. Median age of any SIP decreased in Denmark (from 36 to 29 years) and Sweden (from 41 to 31 years). Incidence rates were higher in men and in individuals on disability pension, and increased more among those with high parental education.ConclusionsWe found similar and stable incidence rates of any SIP in all Scandinavian countries through the observation period. The incidence of alcohol-induced psychosis decreased. The incidence of cannabis-induced psychosis increased.
Dissociated modulations of intranasal vasopressin on prosocial learning between reward-seeking and punishment-avoidance
Authors: Deng Guangzhi , Ai Hui , Qin Lili , Xu Jie , Feng Chunliang , Xu Pengfei 
Published: August 2022

AbstractBackgroundAs an integral ingredient of human sociality, prosocial behavior requires learning what acts can benefit or harm others. However, it remains unknown how individuals adjust prosocial learning to avoid punishment or to pursue reward. Given that arginine vasopressin (AVP) is a neuropeptide that has been involved in modulating various social behaviors in mammals, it could be a crucial neurochemical facilitator that supports prosocial learning.MethodsIn 50 placebo controls and 54 participants with AVP administration, we examined the modulation of AVP on the prosocial learning characterized by reward and punishment framework, as well as its underlying neurocomputational mechanisms combining computational modeling, event-related potentials and oscillations.ResultsWe found a self-bias that individuals learn to avoid punishment asymmetrically more severely than reward-seeking. Importantly, AVP increased behavioral performances and learning rates when making decisions to avoid losses for others and to obtain gains for self. These behavioral effects were underpinned by larger responses of stimulus-preceding negativity (SPN) to anticipation, as well as higher punishment-related feedback-related negativity (FRN) for prosocial learning and reward-related P300 for proself benefits, while FRN and P300 neural processes were integrated into theta (4–7 Hz) oscillation at the outcome evaluation stage.ConclusionsThese results suggest that AVP context-dependently up-regulates altruism for concerning others' losses and reward-seeking for self-oriented benefits. Our findings provide insight into the selectively modulatory roles of AVP in prosocial behaviors depending on learning contexts between proself reward-seeking and prosocial punishment-avoidance.
Variability in caregiver attention bias to threat: A Goldilocks effect in infant emotional development?
Authors: Gunther Kelley E. , Anaya Berenice , Myruski Sarah , Burris Jessica L. , LoBue Vanessa , Buss Kristin A. , Pérez-Edgar Koraly 
Published: August 2022

AbstractAttention biases to threat are considered part of the etiology of anxiety disorders. Attention bias variability (ABV) quantifies intraindividual fluctuations in attention biases and may better capture the relation between attention biases and psychopathology risk versus mean levels of attention bias. ABV to threat has been associated with attentional control and emotion regulation, which may impact how caregivers interact with their child. In a relatively diverse sample of infants (50% White, 50.7% female), we asked how caregiver ABV to threat related to trajectories of infant negative affect across the first 2 years of life. Families were part of a multi-site longitudinal study, and data were collected from 4 to 24 months of age. Multilevel modeling examined the effect of average caregiver attention biases on changes in negative affect. We found a significant interaction between infant age and caregiver ABV to threat. Probing this interaction revealed that infants of caregivers with high ABV showed decreases in negative affect over time, while infants of caregivers with low-to-average ABV showed potentiated increases in negative affect. We discuss how both high andextremepatterns of ABV may relate to deviations in developmental trajectories.
Understanding the prospective associations between neuro-developmental problems, bullying victimization, and mental health: Lessons from a longitudinal study of institutional deprivation
Authors: Rizeq Jala , Kennedy Mark , Kreppner Jana , Maughan Barbara , Sonuga-Barke Edmund 
Published: August 2022

AbstractStudies suggest that children who have experienced neglect are at risk for bullying which in turn increases the risk for poor mental health. Here we extend this research by examining whether this risk extends to the neglect associated with severe institutional deprivation and then testing the extent to which these effects are mediated by prior deprivation-related neuro-developmental problems such as symptoms of inattention, hyperactivity and autism. Data were collected at ages 6, 11, 15, and young adulthood (22–25 years) from 165 adoptees who experienced up to 43 months of deprivation in Romanian Orphanages in 1980s and 52 non-deprived UK adoptees (N = 217; 50.23% females). Deprivation was associated with elevated levels of bullying and neuro-developmental symptoms at ages 6 through 15 and young adult depression and anxiety. Paths from deprivation to poor adult mental health were mediated via cross-lagged effects from earlier neuro-developmental problems to later bullying. Findings evidence how deep-seated neuro-developmental impacts of institutional deprivation can cascade across development to impact social functioning and mental health. These results elucidate cascade timing and the association between early deprivation and later bullying victimization across childhood and adolescence.
A note on contraception, social norms, and growth
Authors: Cavalcanti Tiago , Kocharkov Georgi , Santos Cezar 
Published: August 2022

AbstractWe introduce contraceptives and social norms in an overlapping generations growth model of fertility and human capital. Parents can use costly modern contraceptives to control their family size, and each household’s fertility decision is influenced by the decisions made by others. Given the number of children born, parents decide how much education to provide and how much to save out of their income. We characterize the local dynamics of a stable steady-state equilibrium. Around this steady state, family planning interventions, which reduce the price of modern contraceptives, decrease fertility and increase human and physical capital. The effects of family planning interventions are larger when reproductive externalities are stronger.