bluuebunny/crossref_metadata_2025_split huggingface dataset:
Elucidation of the changes occurring at the proteome level in ovaries of high‐fat diet‐induced obese rats
Authors: Simsek Hayal U. , Albayrak Merve G. B. , Kasap Murat , Simsek Turgay , Akpinar Gurler , Guler Sertac A. , Canturk Nuh Z. 
Published: March 2022

AbstractHigh‐fat diet‐induced obesity adversely affects the female reproductive system. The metabolic changes that the high‐fat diet causes on the ovaries have not been elucidated. Herein, to understand the molecular and cellular mechanisms underlying the effects of long‐term high‐fat diet‐fed, the changes in the global proteomic profile of the rat ovaries were investigated. The female rats were randomly divided into two groups based on their diets: the ones that were fed with the high‐fat diet and the other ones that were fed with the control diet for 18 weeks. To identify differentially expressed proteins, the changes in ovary proteomes were investigated by two‐dimensional electrophoresis coupled to matrix‐assisted laser desorption/ionization‐time‐of‐flight/time‐of‐flight and label‐free quantification with nano‐high performance liquid chromatography to tandem mass spectrometry (nHPLC‐MS/MS). A total of 80 proteins were differentially regulated. The upregulated proteins were involved in responses to chemical and organic substances, cytokines, external stimuli, and lipids. These proteins were particularly associated with vesicles, microbodies, and cell surface proteins. The downregulated proteins were involved in biological processes associated with cellular respiration. Those proteins created a network consisting of proteins involved in aerobic respiration and energy generation. Our results demonstrated that the mechanisms related to energy production in the ovary tissue were particularly affected by the high‐fat diet.
Congenital granular cell tumor: Report of a case with literature review and differential diagnosis
Authors: Singh Arpita , Ghosh Snehashish , Yadav Anjani Kumar , Panthee Anuja 
Published: March 2022

AbstractCongenital granular cell tumor (CGCT) is a rare benign lesion and presents as a fibrous mass arising from the alveolus in the newborn. The prenatal screening of lesions can help in parent counseling, determining the complications, as larger size lesions may interfere with normal delivery and require a cesarean section.
Dementia as a core clinical feature of a patient with aceruloplasminemia
Authors: Ashrafi Farzad , Salari Mehri , Nouri Fatemeh , Shiravi Fatemeh 
Published: March 2022

AbstractAceruloplasminemia is an autosomal recessive disease, caused by systemic iron accumulation due to mutations in the Ceruloplasmin gene. We report two Iranian siblings who have been diagnosed with aceruloplasminemia. Although dementia has not been published as the first neurological feature, one of our cases was presented with pure dementia.
Far migration of an intrauterine contraceptive device from the uterus to the small bowel
Authors: Carroll Alexandria , Paradise Courtney , Schuemann Katie , Schellhammer Shannon Scott , Carlan Steve J. 
Published: March 2022

AbstractA sexually active, asymptomatic 44‐year‐old presented for Intrauterine device (IUD) removal that had been in place for 13 years. IUD removal was unsuccessful as the strings could not be located. Imaging revealed an extrauterine IUD and at surgical removal of the abdominal IUD a small bowel perforation requiring bowel resection was required. Uterine perforation is a rare complication of IUD use occurring in approximately 1–1.3 in 1000. Risk factors for perforation include provider inexperience, retroverted uterus, immobile uterus, and myometrial defect from a previous cesarean delivery or myomectomy.
Magnetite‐Free Sn‐Doped Hematite Nanoflake Layers for Enhanced Photoelectrochemical Water Splitting
Authors: Ahn Hyo‐Jin , Kment Stepan , Yoo Jeong Eun , Truong Nguyen Nhat , Naldoni Alberto , Zboril Radek , Schmuki Patrik 
Published: March 2022

AbstractIn the present work, we report a preparation strategy for hematite phase‐pure photoanodes consisting of Sn‐doped hematite nanoflakes/hematite thin film bilayer nanostructure (Sn‐HB). This approach is based on a two‐step annealing process of pure iron films deposited on fluorine doped tin oxide (FTO) substrates by advanced magnetron sputtering. While the high density hematite ultrathin nanoflakes (HNs) with detrimental iron oxide layers (Fe3O4 and/or FeO) are generated during the first annealing step at 400 °C for two hours, the second thermal treatment at 800 °C for 15 minutes oxidises all the undesired iron oxide phases to a photoactive hematite layer as well as is providing efficient Sn doping of a drop‐casted SnCl4 in order to increase the conductivity. The optimized Sn‐HB shows an around 11 times higher photocurrent density (0.71 mA cm−2 at 1.23 VRHE) compared with a reference hematite photoanode produced from iron foil under the same conditions.
Comparing adult‐child and spousal caregiver burden and potential contributors
Authors: Fenton Anny T.H.R. , Keating Nancy L. , Ornstein Katherine A. , Kent Erin E. , Litzelman Kristin , Rowland Julia H. , Wright Alexi A. 
Published: March 2022

BackgroundAdult‐children caring for a parent with cancer comprise a significant segment of caregivers. Yet less is known about adult‐child caregivers, their burden, or caregivers' and patients' gender's impact, which may differ from the well‐studied spousal caregiver. This knowledge gap may hinder efforts to ameliorate adult‐children's caregiver burden.MethodsWe analyzed caregiver surveys from the Cancer Care Outcomes Research and Surveillance Consortium, a multi‐regional population‐based study of patients with colorectal or lung cancer. Using t tests and multivariate regression models, we assessed whether adult‐child and spousal caregivers' caregiving responsibilities and social/emotional and financial burdens differed and used structural equation models (SEMs) to examine mediating factors.ResultsCompared with spouses/partners (N = 1007), adult‐children (N = 227) spent less time caregiving (14 vs 23 hours/week; P < .001), but experienced higher social/ emotional burden (P < .01). In models adjusted for objective caregiving burden measures and demographics, adult‐children's social/emotional (P < .05) and financial burdens (P < .01) were greater than spouses'. Poor communication quality was associated with greater social/emotional burden for both groups (P < .05). SEMs indicated that gender concordance between caregivers and patients (eg, daughters caring for mothers) and caregiver employment increased the difference between adult‐child and spouses' social/emotional burden, whereas caregiver‐patient relationship quality reduced it.ConclusionsAdult‐children spend less time caregiving than spouses/partners, but have higher social/emotional and financial caregiving burdens, partially due to adult‐children's employment, caregiver‐patients' gender concordance, and relationship quality. Gender concordance's contribution to greater social/emotional burden adds important context to prior findings, indicating female caregivers experience the most burden. Interventions that improve caregiver‐patient communication may reduce both adult‐child and spousal caregiver burden.
Monolayer, Bilayer, and Bulk BSi as Potential Anode Materials of Li‐Ion Batteries
Authors: Samad Abdus , Shafique Aamir , Schwingenschlögl Udo , Ji ZongWei , Luo Guangfu 
Published: March 2022

AbstractMonolayer, bilayer, and bulk BSi are studied to explore their application potential as anode materials of Li‐ion batteries. Structural stability and metallicity are obtained in each case. The Li storage capacities of monolayer and bilayer BSi are 1378 and 689 mAh g−1, respectively, with average open circuit voltages of 1.30 and 0.47 V as well as Li diffusion barriers of 0.48 and 0.27 eV. Bulk BSi realizes a layered structure in the presence of a small amount of Li and its Li diffusion barrier of 0.48 eV is identical to that of graphite and lower than that of bulk Si (0.58 eV). The Li storage capacity of bulk BSi is found to be 689 mAh g−1, i. e., much higher than that of graphite (372 mAh g−1). The volume expansion turns out to be 33 % and the chemical bonds remain intact at full lithiation, outperforming the 72 % volume expansion of bulk Si at the same capacity and thus pointing to excellent cyclability.
Energy‐Efficient Small‐Scale Ammonia Synthesis Process with Plasma‐Enabled Nitrogen Oxidation and Catalytic Reduction of Adsorbed NOx
Authors: Hollevoet Lander , Vervloessem Elise , Gorbanev Yury , Nikiforov Anton , De Geyter Nathalie , Bogaerts Annemie , Martens Johan A. 
Published: March 2022

AbstractIndustrial ammonia production without CO2 emission and with low energy consumption is one of the technological grand challenges of this age. Current Haber‐Bosch ammonia mass production processes work with a thermally activated iron catalyst needing high pressure. The need for large volumes of hydrogen gas and the continuous operation mode render electrification of Haber‐Bosch plants difficult to achieve. Electrochemical solutions at low pressure and temperature are faced with the problematic inertness of the nitrogen molecule on electrodes. Direct reduction of N2 to ammonia is only possible with very reactive chemicals such as lithium metal, the regeneration of which is energy intensive. Here, the attractiveness of an oxidative route for N2 activation was presented. N2 conversion to NOx in a plasma reactor followed by reduction with H2 on a heterogeneous catalyst at low pressure could be an energy‐efficient option for small‐scale distributed ammonia production with renewable electricity and without intrinsic CO2 footprint.
A Rapid and Reversible pH Control Process for the Formation and Dissociation of Lignin Nanoparticles
Authors: Xu Jiayun , Zhou Hao , Zheng Yong , Li Chenyu , Dai Lin , Xu Chunlin , Si Chuanling 
Published: March 2022

AbstractAs a new and green type of nanomaterials, lignin nanoparticles (LNPs) have been considered as high‐value renewable materials for application in many fields. However, the industrialization of LNPs faces many challenges, such as high manufacturing costs and small‐scale production. Here, a simple but rapid and reversible approach for the fabrication of LNPs was provided via switching pH environments. The LNPs were regularly shaped in the acetonitrile/water system, and their size appeared to be very homogeneous. The alternation of forming and dissolving of LNPs could be repeated many times simply by alternately adding acid and alkaline solutions. There was little difference in the molecular structures between the original and regenerated LNPs. In addition, the consumption of solvents for LNPs production was only 200 mL g−1, reduced by more than 10 times compared with conventional solvent exchange methods. The concentration of LNPs in the solution also improved to 5.0 g L−1. This study not only provides a new, simple, and effective strategy for the fabrication of LNPs but also paves the way towards their real green production and application.
Revisiting the improved core confinement simulations for FT‐2 tokamak
Authors: Iorio Riccardo Nicolò , Chône Laurent , Gusakov Evgeniy , Kiviniemi Timo P. , Lashkul Serguey , Leerink Susan 
Published: March 2022

AbstractIn the present paper, we revisit observations performed in FT‐2 tokamak from previous works. Improvements of core confinement are observed and believed to be caused by wide orbits going from collisionless to collisional regimes. Similar phenomena can occur whenever gradient lengths are comparable to the orbit widths at the top of the pedestal and the loss cone is continuously and increasingly filled by heated particles, collisions and turbulent effects. The lower hybrid heating operator is introduced into the ELMFIRE code to increase the ion temperature during the simulations while keeping the edge temperature low with logical boundary condition at the limiter. Particular focus is given on how the radial electric field deviates from the neoclassical value while introducing turbulent effects.
Comparative analysis of inter‐observer variability between conventional reporting system of salivary gland cytology with Milan system for reporting salivary gland cytopathology
Authors: Khan Lubna , Sudarsini Saheeta , Mishra Vandana , Dwivedi Shobha , Kala Chayanika 
Published: March 2022

AbstractBackgroundInterpretation of salivary gland cytology often leads to inter‐observer variability due to heterogenous and complex nature of these lesions. This creates a dilemma regarding their management by clinicians. Proposal of a universal system of reporting of salivary gland lesions leading to agreement in diagnosis and better understanding among clinicians was the need of the hour. Hence Milan system for reporting salivary gland cytopathology (MSRSGC) was proposed in 2015 by the American society of cytopathology and the International Academy of Cytology. Present study was undertaken to assess inter‐observer variability in reporting by conventional system and MSRSGC.Material and methodsOne hundred and seventy‐six cases of salivary gland lesions were subjected to fine needle aspiration cytology. Cases were interpreted by two experienced cytopathologists and were reported by both conventional system and MSRSGC. Histopathological correlation was available in 81 cases.ResultsInter‐observer variability was noted in six cases reported by conventional system and in two cases by MSRSGC. Moreover three cases out six cases had different management protocols while both cases of Milan system for reporting salivary gland cytology had same management. Thirteen cases diagnosed by Milan system and 17 cases diagnosed by conventional system were discordant with histopathological diagnosis.ConclusionMilan system for reporting salivary gland cytology has an edge over conventional system of reporting as it provides better agreement among cytopathologists and better management guidelines for clinicians with the added advantage of assessment of risk of malignancy.
Temperature and barometric pressure affect the activity intensity and movement of an endangered thermoconforming lizard
Authors: Ariano‐Sánchez Daniel , Mortensen Rasmus M. , Wilson Rory P. , Bjureke Peder , Reinhardt Stefanie , Rosell Frank 
Published: March 2022

AbstractGlobal warming is expected to affect movement‐related thermoregulation in ectotherms, but the likely effects on thermoconforming lizards, which spend little energy in thermoregulation behavior, are unclear. We used the Guatemalan beaded lizard (Heloderma charlesbogerti) as a model thermoconforming species to investigate the effects of ambient temperature and barometric pressure (a cue for rain in the study area) on activity intensity and the structure of movement paths. We tracked 12 individuals over a total of 148 animal days during the wet season of 2019 using Global Positioning System tags and triaxial accelerometry. We found a clear positive effect of ambient temperature on activity (using vectorial dynamic body acceleration [VeDBA]) and step length of lizard movements. The movement also became more directional (longer step lengths and smaller turning angles) with increasing ambient temperatures. There was a small negative effect of barometric pressure on VeDBA. We propose that our patterns are indicative of internal state changes in the animals, as they move from a state of hunger, eliciting foraging, which is enhanced by lower temperatures and rainfall to a thermally stressed state, which initiates shelter‐seeking. Our findings highlight the sensitivity of this species to temperature change, show that not all thermoconforming lizards are thermal generalists, and indicate that predicted regional increases in temperature and reduction in rainfall are likely to negatively impact this species by reducing the width of their operational thermal window.
Electrolyte circulation effects in electrochemical performance for different flow fields of all‐vanadium redox flow battery
Authors: Kumar Sanjay , Jayanti Sreenivas , Singh Arvind 
Published: March 2022

AbstractA comparative study of electrochemical performance and hydrodynamic effects on a single cell for all vanadium redox flow batteries has been investigated in the present study. Electrochemical performance of a cell has been conducted with an active area of 414 cm2fitted with serpentine, interdigitated, and enhanced cross‐flow split serpentine (ECFSS) flow fields. The effects of electrolyte circulation rates on the electrochemical performance have been investigated for each flow field, and stable energy efficiency was achieved in 20 charge/discharge cycles for all three flow fields. Higher coulombic, voltage, and energy efficiencies in the serpentine flow field were achieved to be 96%, 82%, and 79%, respectively. The maximum peak power density values for the serpentine, ECFSS, and interdigitated flow field were found to be 158.2, 152.5, and 136.8 mW·cm−2, respectively, at a flow rate of 345 mL·min−1. Furthermore, detailed flow analysis was simulated by using computational fluid dynamics, and these studies postulated the reasons for the higher performance of the serpentine flow field compared to other flow fields.
Design and use of chimeric peptides in a new non‐destructive ecological process applied to the extraction of all trans/9‐cis β‐carotene isomers from Dunaliella salina
Authors: Kouidhi Soumaya , Mnif Wissem , Alqarni Nada , Abdelwahed Soukaina , Redissi Alaeddine , Ammous Nihel , Selmi Boulbaba , Gargouri Ali , Achour Sami , Cherif Ameur , Mosbah Amor 
Published: March 2022

AbstractRecently, β‐carotene has gained tremendous importance as a bioactive molecule due to the growing awareness of the harmful effects of synthetic products. β‐carotene is a high‐value natural pigment that has the highest demand in the global carotenoid market owing to its proven antioxidant properties relevant for several diseases. To date, Dunaliella salina is the most important producer of natural β‐carotene and is the subject of important industrial efforts. However, the extraction of β‐carotene remains challenging since all the proposed techniques present a risk of product contamination or loss of quality due to solvent residuals and low yields. The purpose of this study was to set up a green, ecological, and innovative process of extraction of the two major β‐carotene isomers from the halophilic microalgae Dunaliella salina. Based on molecular modeling, docking, and drug design, we conceived and synthesized two chimeric peptides (PP2, PP3) targeting specifically the two major isomers: all‐trans or 9‐cis β‐carotene. The experimental protocol used in this study demonstrated the ability and the efficacy of those two peptides to cross the cell membrane and bind with high affinity to β‐carotene isomers and exclude them toward the extracellular medium while preserving the integrity of living cells. Interestingly, the tested peptides (PP2, PP3) exhibit significant β‐carotene extraction yields 58% and 34%, respectively, from the total of the β‐carotene in microalgae cells. In addition to its simplicity, this process is fast, independent of the source of the β‐carotene, and selective. These results would allow us to set up a green, ecological, and very profitable process of extraction from microalgae containing high amounts of β‐carotene. Our innovative approach is highly promising for the extraction of Dunaliella salina biomass on an industrial scale.
Occupational safety and health guidelines in relation to COVID‐19 risk, death risk, and case‐fatality proportion: An international, ecological study
Authors: Roberts Morgan , Thygerson Steven M. , Beard John D. , Clark Camille , Montague Emma 
Published: March 2022

AbstractBackgroundCoronavirus disease 2019 (COVID‐19) began in 2019 with several unknown factors. The World Health Organization (WHO) subsequently developed COVID‐19 occupational safety and health (OSH) guidelines to reduce occupational COVID‐19 transmission. Many countries also developed their own COVID‐19 OSH guidelines, but whether these guidelines included WHO's guidelines and whether including WHO's guidelines in countries' COVID‐19 OSH guidelines reduced COVID‐19 transmission is unknown.ObjectivesThe objectives of our study were to (1) compare the COVID‐19 OSH guidelines of several countries to WHO's OSH guidelines, (2) estimate associations between characteristics of countries and their OSH guidelines and the number of WHO's OSH guidelines included in countries' OSH guidelines, and (3) estimate associations between WHO's OSH guidelines included in countries' OSH guidelines and COVID‐19 risk, death risk, and case‐fatality proportion.MethodsThis study represents international, ecological research of 36 countries from all six world health regions. Countries' COVID‐19 OSH guidelines were compared with WHO's OSH guidelines. Linear regression models adjusted for potential confounders were used to estimate associations of interest.ResultsThe median number of WHO's 15 COVID‐19 OSH guidelines included in countries' COVID‐19 OSH guidelines was eight. Countries' COVID‐19 OSH guidelines focused on workers included significantly more of WHO's COVID‐19 OSH guidelines than countries' COVID‐19 OSH guidelines focused on general populations. Including “provide personal protective equipment for workers” and “create workplace policy for wearing personal protective equipment” in countries' COVID‐19 OSH guidelines were significantly related to decreased COVID‐19 risk, death risk, and/or case‐fatality proportion.ConclusionsCountries' COVID‐19 OSH guidelines should include WHO's guidelines, focus on workers, and include “provide personal protective equipment for workers” and “create workplace policy for wearing personal protective equipment.”
Retracted: Internet of things in the management of chronic diseases during the COVID‐19 pandemic: A systematic review
Authors: Shamsabadi Ahmadreza , Pashaei Zahra , Karimi Amirali , Mirzapour Pegah , Qaderi Kowsar , Marhamati Mahmoud , Barzegary Alireza , Fakhfouri Amirata , Mehraeen Esmaeil , SeyedAlinaghi SeyedAhmad , Dadras Omid 
Published: March 2022

AbstractIntroductionThe use of new technologies such as the Internet of Things (IoT) in the management of chronic diseases, especially in the COVID pandemics, could be a life‐saving appliance for public health practice. The purpose of the current study is to identify the applications and capability of IoT and digital health in the management of the COVID‐19 pandemic.MethodsThis systematic review was conducted by searching the online databases of PubMed, Scopus, and Web of Science using selected keywords to retrieve the relevant literature published until December 25th, 2021. The most relevant original English studies were included after initial screening based on the inclusion criteria.ResultsOverall, 18 studies were included. Most of the studies reported benefits and positive responses in the form of patients' and healthcare providers' satisfaction and trust in the online systems. Many services were provided to the patients, including but not limited to training the patients on their conditions; monitoring vital signs and required actions when vital signs were altered; ensuring treatment adherence; monitoring and consulting the patients regarding diet, physical activity, and lifestyle.ConclusionIoT is a new technology, which can help us improve health care services during the COVID‐19 pandemic. It has a network of various sensors, obtaining data from patients. We have found several applications for this technology. Future studies can be conducted for the capability of other technologies in the management of chronic diseases.