bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inventario de Amphipoda (Peracarida: Senticaudata y Amphilochidea) del Río Miño Internacional, Península Ibérica
Authors: Gomes Nuno , Costa‍ Dimítri A. , Cantallo Harold , Antunes Carlos 
Published: September 2022

Los crustáceos son un grupo diverso y abundante de la fauna invertebrada de la comunidad litoral y estuarina. Este estudio presenta el primer compendio sobre la fauna de anfípodos en el estuario del río Miño, Península Ibérica, recolectada a través de captura accidental de pesca de angula, y muestreos con draga y arrastre de vara. Se examinaron un total de 100 especímenes pertenecientes a 18 familias, 23 géneros y 34 especies (23 nuevos registros para el río Miño, incluyendo un nuevo registro para Portugal, Parametopa kervillei Chevreux, 1901). Las famílias más representadas fueron Ampeliscidae, con 7 especies del género Ampelisca, y Gammaridae, con 3 especies de géneros distintos. Además se proporciona para todas las espécies un breve diagnóstico, notas ecológicas, distribución y figuras con el objetivo de proporcionar apoyo taxonómico en futuros proyectos medioambientales en esta zona.
Presencia de Parasteatoda lunata (Clerck, 1757) (Araneae: Theridiidae) en la Comunidad de Madrid (España), con notas sobre su tela y comportamiento antidepredatorio
Authors: Pinilla Rosa Manuel 
Published: September 2022

La araña terídida Parasteatoda lunata (Clerck, 1757) es citada por primera vez para el centro de la península ibérica. Parece estar localmente asociada al clima eurosiberiano y su establecimiento en los hábitats podría depender principalmente de la presencia de objetos con forma y posición adecuadas. Los ejemplares se dejaron caer al suelo, inmóviles, como respuesta defensiva.
Amateurisme ou idéologie ?
Authors: Ghorbal Karim 
Published: September 2022

Contrairement à une opinion répandue, l’Église d’Angleterre au xviiie siècle, premier propriétaire terrien du royaume, s’est révélée un piètre gestionnaire, laissant se dégrader ses revenus dans une période pourtant faste et souvent qualifiée de « révolution agricole ». Christopher Clay, dans un article publié en 1980, fut le premier à identifier ce phénomène et l’attribua à l’incompétence du clergé de l’époque. Cet article propose de prolonger son analyse à travers l’étude de la pratique gestionnaire de Josiah Tucker, doyen de Gloucester de 1758 à 1799 et économiste reconnu. Compétent et conscient de ce problème, il a tenté toute sa vie de professionnaliser son Église et d’augmenter ses revenus pour lui garantir son indépendance vis-à-vis du pouvoir politique. Il n’a cependant pas réussi à convaincre ses collègues de l’intérêt de sa démarche, qui la refusèrent principalement pour des raisons idéologiques.
Identification of the chemical components of ethanol extract of Chenopodium ambrosioides and evaluation of their in vitro antioxidant and anti tumor activities
Authors: Li Jiao , Si Chaojin , Hong Wenjing , Xia, Chaoguo , Yang Yuqi , He Yiting , Su Min , Long Xuehua , Zhang Hong 
Published: September 2022

Purpose: To determine the characteristic chemical components of the ethanol extract of Chenopodium ambrosioides and evaluate their antioxidant and anti-tumor effects in vitro.
Methods: The plant powder (5 g) was extracted with 1 L of 80 % ethanol at room temperature for 45 min, and then placed at 60 oC at varying microwave power and duration to obtain optimal extraction conditions. Characteristic chemical components were detected using ultra-high performance liquid chromatography quadrupole time of flight mass spectrometry (UPLC-Q-TOF-MS/MS). Kaempferitrin was isolated from the 80 % ethanol extract using a D101 macroporous resin column, and its content was assessed by high performance liquid chromatography (HPLC). The antioxidant effect of kaempferitrin was evaluated by its ability to scavenge 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azinobis-(3-ethylbenzthiazoline-6-sulphonate) (ABTS) radicals, while its anti-proliferation activity in human liver cancer cells SMMC-7721 was determined using cell counting kit-8 (CCK-8) reagent.
Results: Three characteristic components of ethanol extract of C. ambrosioides were obtained, namely, kaempferitrin, kaempferol-3-O-apigenin-7-O-rhamnoside and kaempferol-3-O-acetylapigenin-7-O-rhamnoside. Kaempferitrin was shown to possess strong DPPH radical and moderate ABTS radical scavenging activities. Kaempferitrin significantly inhibited the proliferation of SMMC-7721 cells at doses of 4 and 8 μg/mL, with half-maximal concentration (IC50) of 0.38 μM (p < 0.05).
Conclusion: Kaempferitrin extracted from C. ambrosioides has antioxidant and anti-tumor activities. The results reported here indicate that C. ambrosioides may have potential use in herbal medicine practice.
Five-year Ground-based Observation Trend of PM2.5 and PM10, and Comparison with MERRA-2 Data over India
Authors: Alang Ashmeet Kaur , Aggarwal Shankar G. 
Published: September 2022

Abstract
A comprehensive analysis of pollutant’s trend and their measurement techniques are crucial for evaluating the air quality, and thereby helpful in formulating better control policies. In this report, we summarise ground based PM2.5 and PM10 data report in India (2015–2019). The important points discussed here are: (i) review of the ground-based data of PM2.5 and PM10 and the techniques used, (ii) mapping of the data over India with spatial and temporal distribution so that better understanding on PM pollution level can be made, (iii) identifying the technological gaps in measurement of PM concentration in India, and (iv) evaluation of MERRA-2’s (Modern-Era Retrospective Analysis for Research and Applications, Version 2) simulation of PM2.5 against surface measurements in India to better understand biases for spatial and seasonal distribution, and then (v) suggestions for better PM measurement protocols, policies and metrological aspects for both measurement and control policies. It is observed that the amount of ground data on ambient monitoring of fine PM is insufficient and has several inconsistencies which require adequate attention. In India, not much work has been done on developing certified reference materials, traceable standards and calibration facility for particulate matter measurement which is a crucial step to ensure quality checks. Further, the comparison of MERRA-2 and ground PM2.5 concentrations revealed huge discrepancies with underestimating PM2.5 measurements in highly polluted regions like the Indo-Gangetic plain, especially during winter when pollution load was high. Better PM2.5 agreement was found in summer and monsoon season, based on performance statistics explained in this paper. Inconsistencies between MERRA-2 and ground PM2.5 are partly due to few limitations in MERRA-2 reanalysis method which are discussed in this paper, apart from several issues in ground-based observation. The aim of this review and comparison is to highlight such issues and give more attention to the importance of data quality assurance for effective air quality management. The present study may be helpful for the researchers in evaluating and choosing appropriate reanalysis products for their future studies.
Papillary Renal Neoplasm With Reverse Polarity: A Clinical, Pathologic, and Molecular Study of 8 Renal Tumors From a Single Institution
Authors: Nova-Camacho Luiz M. , Martin-Arruti Maialen , Díaz Irune Ruiz , Panizo-Santos Ángel 
Published: September 2022

Context.—
In 2019, papillary renal neoplasm with reverse polarity (PRNRP) was defined as a new neoplasm because it has a predominately tubulopapillary pattern lined by a single layer of cuboidal and eosinophilic cells with apically located round nuclei. Immunohistochemically, this neoplasm showed expression of GATA-3 and L1CAM and had recurrent KRAS mutations.

Objective.—
To estimate the incidence of PRNRP and provide 8 additional cases with some variations in the morphology.

Design.—
We reviewed 1627 renal tumors from our hospital during a 21-year period (2000–2020). We reexamined 196 papillary renal cell carcinomas and selected those that met the diagnostic criteria for PRNRP.

Results.—
We found 8 cases consistent with PRNRP. The median age of the patients was 64.75 years; 7 patients were male, and 1 was female. Two patients had end-stage renal disease. No recurrence, metastasis, or tumor-related death occurred in a mean follow-up period of 67.62 months. Tumor size ranged from 1.6 to 3.7 cm. All cases were pT1. Seven cases (7 of 8; 87.5%) had predominantly cystic changes, and 1 had solid architecture. No foamy cells, clear cell change, or psammoma bodies were seen in any cases. All cases were positive for CK7, EMA, GATA3, and L1CAM. KRAS gene mutation was detected in 5 cases (5 of 8; 62.5%).

Conclusions.—
PRNRP represents 4.08% (8 of 196 cases) of papillary renal cell carcinomas and 0.49% (8 of 1627 cases) of all renal tumors in the 21-year period in our series. In our study, all cases exhibited an indolent clinical course. This supports that PRNRP has characteristic morphologic and molecular features.
A content analysis of the reliability and quality of Youtube videos as a source of information on health-related post-COVID pain
Authors: Ozduran Erkan , Büyükçoban Sibel 
Published: September 2022

Background
The use of the internet as a source of information has increased during the pandemic, and YouTube has become an increasingly important source of information on Coronavirus disease 2019 (COVID-19). In the long COVID picture, which occurs when symptoms related to COVID-19 last longer than 1 month, pain involving the musculoskeletal system affects the quality of life quite negatively. The aim of this study was to investigate the informational value and quality of YouTube videos related to post-COVID pain.

Methods
In this study, 180 videos were listed using the search terms “pain after COVID,” “post-COVID pain,” and “long COVID and pain”(15 April 2022). Videos were classified according to video parameters and content analysis. Quality, reliability and accuracy of the videos were determined with the Global Quality Score (GQS), the Journal of American Medical Association (JAMA) Benchmark Criteria and the Modified DISCERN Questionnaire, respectively.

Results
One hundred videos that met the inclusion criteria were included in the assessment. Of these videos, 74 were found to be of low quality, 14 of moderate quality, and 12 of high quality; 21% contained insufficient data, 73% contained partially sufficient data, and 6% contained completely sufficient data. Videos uploaded by academic sources (66.7%) and physicians (12.5%) made up the majority of the high-quality group. A statistically significant correlation was found between the source of upload and number of views (p = 0.014), likes (p = 0.030), comments (p = 0.007), and video duration (p = 0.004). Video duration was found to have a poor positive correlation with GQS (r = 0.500), JAMA (r = 0.528), and modified DISCERN (r = 0.470) scores (p < 0.001).

Conclusion
The findings of this study revealed that the majority of YouTube videos on post-COVID pain had low quality and partially sufficient data. High-quality videos were found to have longer durations and were uploaded by academic sources and physicians. The fact that only videos with English content at a certain time can be counted among the limitations. For patients suffering from post-COVID pain whose access to healthcare services was interrupted during the COVID pandemic, YouTube can be considered as an alternative source as well as a means of telerehabilitation. It can be argued that higher quality videos created by healthcare professionals could aid in patient education in the future.
Risk Factors for Breast Malignancy among Women Presenting with Breast Masses in a Teaching Hospital in Lagos, Nigeria
Authors: Mirian Akujuobi, Obianuju , Angela Ayonote, Uzoramaka , Nneamaka Ogbonna, Adaobi 
Published: September 2022

Background: Breast cancer is the commonest female malignancy globally with increasing prevalence in Nigeria. This study aimed at identifying factors associated with malignant breast masses among women with breast masses receiving care at the Lagos University Teaching Hospital (LUTH).
Materials: This cross-sectional, descriptive study investigated 100 women with breast masses by history-taking, clinical breast examination and biopsy for histopathology assessment. Sociodemographic characteristics, family, social, gynecologic, and obstetric history were obtained, and features of breast mass on examination were documented and histology specimens were taken for assessment. The proportion of women with malignant breast masses by biopsy was calculated. Using binary logistic regression analysis, factors associated with malignant breast masses were identified. Significance level was set at p < 0.05.
Results: The mean age of participants was 39.4±13.4 years. Most were married (63.0%), overweight (53.0%) and had tertiary level of education (58.0%). The right breast was affected in 56% of women, while most breast masses were oval (49.0%). History of breast pain, exclusive breast feeding and nipple retraction was reported in 76.0%, 35.0% and 17.0% respectively. Malignant breast masses were identified in 46.0% of women and associated factors included increasing age (OR=10.95 – 442.00; p<0.05), married women (OR=6.96; p: 0.001), obesity (OR= 16.20; p: 0.003). Clinical symptoms associated with malignant breast mass included history of previous breast mass (OR = 3.93; p: 0.028), breast pain (OR = 3.07; p: 0.023), nipple retraction (OR=7.44;0.003) and nipple discharge (OR = 10.24; 0.003).
Conclusion: The study found that a high percentage of breast masses assessed by biopsy were malignant among the studied populace. Factors significantly associated with increased risk of malignant breast mass included increasing age, obesity, and marital status. We recommend lifestyle modification as well as adoption of primordial and primary prevention measures in tackling problems related with breast cancer among Nigerian women. This should also include the improvement of access to such services.
Reevaluating Corticosteroid Classification Models in Patient Patch Testing
Authors: Chen Joyce Y. , Yiannias James A. , Hall Matthew R. , Youssef Molly J. , Drage Lisa A. , Davis Mark D. P. , Yang Yul W. 
Published: September 2022

ImportanceIndividuals with allergic contact dermatitis to one topical corticosteroid may also react to other corticosteroids. Corticosteroid classification models have been proposed to predict such copositivity, recommend representative screening corticosteroids, and guide allergen avoidance.ObjectiveTo use patient data to determine copositivity patterns between corticosteroids and evaluate against previous corticosteroid classification models.Design, Setting, and ParticipantsThis qualitative study included a retrospective analysis of the Mayo Clinic Contact Dermatitis Group corticosteroid patch test data from 2010 to 2019. Among patients undergoing patch testing with the Mayo Clinic’s standard or steroid series who consented to research participation, 5637 patients were included in the analysis. Copositivity rates were determined between corticosteroids and analyzed by hierarchical clustering for comparison to previous classification models.Main Outcomes and MeasuresThe frequency of patch test positivity to each of the analyzed corticosteroids was noted and compared with previously published patch test positivity rates. Copositivity rates between each pair of corticosteroids were determined, and overall copositivity patterns were analyzed and evaluated against known steroid classes.ResultsA total of 49 472 individual patches were applied to 5637 patients, testing 18 corticosteroids. Patch test positivity rates ranged between 0.3% and 4.7%. The fluocinonide positivity rate corresponded to the highest copositivity rate with other corticosteroids (mean [SD], 50.7% [26.1%]). Tixocortol-21-pivalate, 0.1%, and tixocortol-21-pivalate, 1%, positivity rates corresponded to the lowest copositivity rates (mean [SD], 4.1% [1.7%] and 3.6% [1.4%], respectively). Hierarchical clustering elucidated patterns that did not support previous corticosteroid classification models.Conclusions and RelevanceIn this qualitative study, copositivity rates were variable between corticosteroids, and overall patch test positivity for allergy to topical corticosteroids was rare. Previously published corticosteroid classifications are not supported by real patient-derived data and may not be accurate in predicting corticosteroid copositivity.
Superstructure Variation and Improved Cycling of Anion Redox Active Sodium Manganese Oxides Due to Doping by Iron
Authors: Qi Xiaodong , Wu Langyuan , Li Zhiwei , Xiang Yuxuan , Liu Yunan , Huang Kangsheng , Yuval Elias , Aurbach Doron , Zhang Xiaogang 
Published: September 2022

AbstractAnionic redox provides an effective way to overcome the capacity bottleneck of sodium‐ion batteries. A dominant role is played by the arrangement of alkali A and transition metal M in the NaxAyM1‐yO2 superstructure. Here, in situ X‐ray diffraction and ex situ 7Li nuclear magnetic resonance of P2 type Na0.6Li0.2Mn0.8O2 with ribbon‐ordered superstructure illustrate structural changes and explain the evolution of the electrochemical behavior of electrodes comprising this active mass, during cycling. Upon substitution of a small amount of manganese by iron, Na0.67Li0.2Mn0.73Fe0.07O2 is formed with a honeycomb‐ordered superstructure. Experimental characterizations and theoretical calculations elucidate the effect of iron on oxygen redox activity. The iron‐doped material considerably outperforms the undoped Na0.6Li0.2Mn0.8O2 as a cathode material for rechargeable Na‐ion batteries. This research reveals the effect of superstructure transformation on the electrochemical properties and offers a new perspective on element substitution in anionic redox active cathode materials.
Effects of stocking density on the performance of lettuce (Lactuca sativa) in small‐scale lettuce‐Nile tilapia (Oreochromis niloticus L.) aquaponic system
Authors: Sabwa Josiah A. , Manyala Julius O. , Masese Frank O. , Fitzsimmons Kevin , Achieng Alfred O. , Munguti Jonathan M. 
Published: September 2022

AbstractAquaponics incorporates aquaculture with hydroponics, whose principles and operations largely remain untested. Currently, there is a knowledge gap on the performance of aquaponic systems used for fish production under different stocking densities. This may hinder adoption and generally retard the development of aquaponic culture systems for fish and vegetation production in Kenya. The objective of the current study was to determine the effect of fish stocking density on the growth performance of lettuce (Lactuca sativa) and Nile tilapia (Oreochromis niloticus) reared in a coupled aquaponic system. We used three fish stocking densities of 150, 300 and 450 fish m−3, each replicated five times. For each treatment or fish stocking density, 16 lettuces were planted m−2 as the planting density. We monitored the following water quality parameters to determine the effects of fish stocking density on water quality; pH, total ammonium–nitrogen (TAN), nitrates , . In the different stocking densities (450, 300 and 150 fish m−3), the water quality parameters ranged from dissolved oxygen: 4–7 mg L−1; pH: 6.3–7.3; TAN: 0.32–0.57 mg L−1; : 0.13–0.36 mg L−1 and : 0.020–0.046 mg L−1. The final weight of the Nile tilapia fingerlings was 25.2 ± 4.2, 32.0 ± 3.8 and 42.6 ± 3.1 g for 450, 300 and 150 fish m−3, respectively. The biomass of lettuce was statistically different (p < 0.005) and increased with increasing stocking density as 166.4 ± 9.8, 276.8 ± 23.2 and 304.6 ± 23.2 g for 150, 300 and 450 fish m−3, respectively. Adopting the intermediate stocking density of 300 fish m−3, which gave the best performance of the aquaponic system, is therefore highly recommended.
Interactive soybean variable‐rate seeding simulator for farmers
Authors: Correndo Adrian , McArtor Brett , Prestholt Aaron , Hernandez Carlos , Kyveryga Peter M. , Ciampitti Ignacio A. 
Published: September 2022

AbstractSeed expense is a critical component affecting soybean (Glycine maxL.) production cost. Achieving potential benefits of adjusting seeding rates by yield environment requires translation from theory to practice through decision support tools. This article introduces the soybean variable‐rate seeding (VRS) simulator, an interactive web‐tool designed to facilitate VRS decisions. A group of agronomists and farmers provided input and feedback to the tool's original design, usability, interactive features, and tool outputs. The simulator generates variable rate seeding recommendations by (a) aggregating and classifying 3 yr of historical soybean yield maps using either yield level (low, medium, or high) or temporal yield stability (stable or unstable) classes, and (b) estimating the difference between the farmers current uniform seeding rate and the optimal seeding rates calibrated for different yield environments of the U.S. Midwest region. For each yield environment, the tool suggests a seeding rate change accompanied by an expected yield increase. Marginal economic and break‐even price analyses of each VRS prescription choice are also provided considering soybean plant survival rate, seed cost, market price, and crop production costs. A step‐by‐step description is provided using a dataset of real, historical, on‐farm soybean yield maps to illustrate the tool's features and limitations. Simulated results indicate that compared to typical fixed seeding rate choices, following the tool's recommendations could improve profits between US$5 and 57 ha–1. The development of this tool contributes to a growing trend of user‐friendly interfaces that assist in translating core agronomic knowledge into practical solutions.
Contractility detection of isolated mouse papillary muscle using myotronic Myostation‐Intact device
Authors: Lian Hong , Qin Zhuyun , Wu Mengge , Zuo Peipei , Bai Lina , Lu Minjie , Li Lulu , Zhang Haitao 
Published: September 2022

AbstractBackgroundTo understand the relationship between myocardial contractility and external stimuli, detecting ex vivo myocardial contractility is necessary.MethodsWe elaborated a method for contractility detection of isolated C57 mouse papillary muscle using Myostation‐Intact system under different frequencies, voltages, and calcium concentrations.ResultsThe results indicated that the basal contractility of the papillary muscle was 0.27 ± 0.03 mN at 10 V, 500‐ms pulse duration, and 1 Hz. From 0.1 to 1.0 Hz, contractility decreased with an increase in frequency (0.45 ± 0.11–0.10 ± 0.02 mN). The voltage‐initiated muscle contractility varied from 3 to 6 V, and the contractility gradually increased as the voltage increased from 6 to 10 V (0.14 ± 0.02–0.28 ± 0.03 mN). Moreover, the muscle contractility increased when the calcium concentration was increased from 1.5 to 3 mM (0.45 ± 0.17–1.11 ± 0.05 mN); however, the contractility stopped increasing even when the concentration was increased to 7.5 mM (1.02 ± 0.23 mN).ConclusionsOur method guaranteed the survivability of papillary muscle ex vivo and provided instructions for Myostation‐Intact users for isolated muscle contractility investigations.