bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy and safety of pre-operative individual topical mydriatic and anaesthetic versus an intracameral fixed-dose combination of two mydriatics and an anaesthetic for phacoemulsification – A comparative study
Authors: Kataria Kajal Haribhai , Bhagat Purvi Raj , Sedani Kanan Vimal Bhai , Mehta Himarshi Nikhilkumar 
Published: April 2022

Objectives:
Intracameral fixed combination of mydriatic and anaesthetic is a new method for inducing and maintaining intraoperative mydriasis and analgesia during cataract surgery. The purpose of our study was to evaluate the efficacy and safety of an intracameral fixed-dose combination of phenylephrine 0.31%, tropicamide 0.02%, and lidocaine 1% during phacoemulsification in comparison to the standard pre-operative topical regimen.

Materials and Methods:
Fifty patients undergoing phacoemulsification were randomly divided into two groups, A and B. Surgery was performed by a single surgeon, using standard regimen in Group A and using the intracameral formulation in Group B. The outcome measures were pupil size, patient perception of pain and overall comfort, surgeon rating of overall experience, and safety.

Results:
Post-dilatation, the pupillary diameter was 7.7 ± 1.3 mm and 5.5 ± 1.2 mm, respectively, for Groups A and B which was statistically significant. For the perception of pain as well as overall comfort, in Group A, five patients rated 4 and 20 patients rated 5, and in Group B, two patients rated 4 and 23 rated 5. The surgeon rating for all patients of Group A was 5 but in Group B, for three patients, it was 4 because of inadequate and ill sustained mydriasis. No complications occurred in either group.

Conclusion:
Intracameral fixed combination of mydriatic and analgesic is safe and effective for use by experienced ophthalmologists and in uncomplicated cataract, providing a reduced pre-operative time; but because of the variable, lesser and ill sustained mydriasis, it may be avoided in complicated cataracts and by novice surgeons.
Bibliometric overview of the Top 100 most cited articles on hydrocephalus
Authors: Albrahim Mohammed , Almutairi Othman T. , Alhussinan Modhi A. , Alotaibi Fahad E. , Bafaquh Mohammed 
Published: April 2022

Background:
Hydrocephalus is one of the most common brain disorders and numerous articles were published to address the clinical aspect and its management. This study aims to highlight the most influential work on hydrocephalus on bibliometric basis.

Methods:
A thorough search of Scopus database was performed using the word “hydrocephalus.” The 100 most cited articles were retrieved, and variables of importance were collected including the article’s title, 1st author affiliation, country of origin, year and journal of publication, article’s category, and citation count according to Scopus and Google scholar databases.

Results:
The 100 most cited articles were thoroughly analyzed. Publication dates ranged from 1946 to 2014, with most articles (45) published between 1998 and 2007. The mean number of citations per publication was 201 with total of 20,177 citations. The United States of America contributed half of the articles. The leading institution was the Canadian hospital for Sick Children University of Toronto having published 5 articles. Hydrocephalus in general and normal pressure hydrocephalus was the two major categories addressed with most studies fall under the topic of surgical management. Neurosurgery was the specialty with the greatest contribution (47%). The articles were published in 46 different journals led by the Journal of Neurosurgery with total of 17 articles.

Conclusion:
This bibliometric analysis delineates the landmark publications in hydrocephalus. The listed articles depict the myriad of studied aspects historically which helps in understanding hydrocephalus overall in evidence-based module for neurosurgeons and non-neurosurgeons.
A scoping review on the challenges, improvement programs, and relevant output metrics for neurotrauma services in major trauma centers
Authors: Dasic Davor , Morgan Lucy , Panezai Amir , Syrmos Nikolaos , Ligarotti Gianfranco K.I. , Zaed Ismail , Chibbaro Salvatore , Khan Tariq , Prisco Lara , Ganau Mario 
Published: April 2022

Background:
For a neurotrauma unit to be defined as a structured neurotrauma service (NS) the following criteria must be satisfied: A dedicated neurointensive care unit, endovascular neuroradiology, in-hospital neurorehabilitation unit and helicopter platform within the context of a Level I trauma center. Designing an effective NS can be challenging, particularly when considering the different priorities and resources of countries across the globe. In addition the impact on clinical outcomes is not clearly established.

Methods:
A scoping review of the literature spanning from 2000 to 2020 meant to identify protocols, guidelines, and best practices for the management of traumatic brain injury (TBI) in NS was conducted on the US National Library of Medicine and National Institute of Health databases.

Results:
Limited evidence is available regarding quantitative and qualitative metrics to assess the impact of NSs and specialist follow-up clinics on patients’ outcome. Of note, the available literature used to lack detailed reports for: (a) Geographical clusters, such as low-to-middle income countries (LMIC); (b) clinical subgroups, such as mild TBI; and (c) long-term management, such as rehabilitation services. Only in the last few years more attention has been paid to those research topics.

Conclusion:
NSs can positively impact the management of the broad spectrum of TBI in different clinical settings; however more research on patients’ outcomes and quality of life metrics is needed to establish their efficacy. The collaboration of global clinicians and the development of international guidelines applicable also to LMIC are warranted.
Adenomyosis-associated recurrent acute cerebral infarction mimicking Trousseau’s syndrome: A case study and review of literature
Authors: Arai Nobuhiko , Yachi Kazunari , Ishihara Ryutaro , Fukushima Takao 
Published: April 2022

Background:
Adenomyosis is a common and benign uterine disease. Acute cerebral infarction (CI) associated with adenomyosis is rarely reported and difficult to treat. We experienced successful treatment for this disease.

Case Description:
A 50-year-old woman presented with a 2-day history of visual disturbance. Magnetic resonance imaging showed multiple tiny diffusion-weighted high-density spots on several lobes. No common risk factors for stroke were detected. Cancer antigen 125 level was 999 U/mL, along with massively expanded uterus and adnexa. Based on the diagnosis of benign adenomyosis, Xa inhibitor and GnRH agonists were administered for CI and adenomyosis, respectively. Acute CI recurred 7 days after admission. We suspected a relationship between infarction and adenomyosis and concluded hysterectomy as a proper treatment strategy based on the literature. Eighteen months after hysterectomy, no recurrence of CI without anti-thrombus medications has been detected.

Conclusion:
Hysterectomy is a radical therapy that is effective in preventing acute CI due to adenomyosis associated with ischemic symptoms.
Effective Strategies for Improving Primary School Students’ English Reading Skills from the Perspective of Core Literacy
Authors: Zhou Chunmei 
Published: April 2022

Primary education, guided by the cultivation of disciplinary core literacy, places a greater emphasis on students’ autonomy and is committed to promoting students’ all-round development. English reading is one of the main ways for students to acquire English knowledge. Although it is a fundamental learning point in English teaching, it poses challenges to English teaching in primary schools. This paper makes a detailed analysis of the current state of English reading education for primary school students from the perspective of core literacy, and then proposes effective strategies for improving students’ English reading skills.
Pertussis surveillance results from a French general practitioner network, France, 2017 to 2020
Authors: Debin Marion , Launay Titouan , Rossignol Louise , Ait El Belghiti Fatima , Brisse Sylvain , Guillot Sophie , Guiso Nicole , Levy-Bruhl Daniel , Merdrignac Lore , Toubiana Julie , Blanchon Thierry , Hanslik Thomas 
Published: April 2022

Introduction
In France, three complementary surveillance networks involving hospitals and paediatrician practices currently allow pertussis surveillance among infants (<1 year old) and children (1–12 years old). Data on incidences among adolescents (13–17 years old) and adults (≥ 18 years) are scarce. In 2017, a sentinel surveillance system called Sentinelles network, was implemented among general practitioners (GPs).

Aim
The purpose of Sentinelles network is to assess pertussis incidence, monitor the cases’ age distribution and evaluate the impact of the country’s vaccination policy. We present the results from the first 4 years of this surveillance.

Methods
GPs of the French Sentinelles network reported weekly numbers of epidemiologically or laboratory-confirmed cases and their characteristics.

Results
A total of 132 cases were reported over 2017–2020. Estimated national incidence rates per 100,000 inhabitants were 17 (95% confidence interval (CI): 12–22) in 2017, 10 (95% CI: 6–14) in 2018, 15 (95% CI: 10–20) in 2019 and three (95% CI: 1–5) in 2020. The incidence rate was significantly lower in 2020 than in 2017–2019. Women were significantly more affected than men (83/132; 63% of women, p = 0.004); 66% (87/132) of cases were aged 15 years or over (median age: 31.5 years; range: 2 months–87 years). Among 37 vaccinated cases with data, 33 had received the recommended number of doses for their age.

Conclusions
These results concur with incidences reported in other European countries, and with studies showing that the incidences of several respiratory diseases decreased in 2020 during the COVID-19 pandemic. The results also suggest a shift of morbidity towards older age groups, and a rapid waning of immunity after vaccination, justifying to continue this surveillance.
Social conformism and confidence in systems as additional psychological antecedents of vaccination: a survey to explain intention for COVID-19 vaccination among healthcare and welfare sector workers, France, December 2020 to February 2021
Authors: Moirangthem Simi , Olivier Cyril , Gagneux-Brunon Amandine , Péllissier Gérard , Abiteboul Dominique , Bonmarin Isabelle , Rouveix Elisabeth , Botelho-Nevers Elisabeth , Mueller Judith E 
Published: April 2022

Background
The start of the COVID-19 vaccination campaign among French healthcare and welfare sector workers in January 2021 offered an opportunity to study psychological antecedents of vaccination in this group.

Aim
We explored whether knowledge and attitude items related to social conformism and confidence in systems contributed to explaining intention for COVID-19 vaccination.

Methods
We developed a knowledge and attitude questionnaire with 30 items related to five established and two hypothetical psychological antecedents of vaccination (KA-7C). The online questionnaire was distributed from 18 December 2020 to 1 February 2021 through chain-referral via professional networks, yielding a convenience sample. We used multivariable logistic regression to explore the associations of individual and grouped KA-7C items with COVID-19 vaccine intention.

Results
Among 5,234 participants, the vaccine intention model fit (pseudo R-squared values) increased slightly but significantly from 0.62 to 0.65 when adding social conformism and confidence in systems items. Intention to vaccinate was associated with the majority opinion among family and friends (OR: 11.57; 95% confidence interval (CI): 4.51–29.67) and a positive perception of employer’s encouragement to get vaccinated (vs negative; OR: 6.41; 95% CI: 3.36–12.22). The strongest association of a knowledge item was identifying the statement ‘Some stages of vaccine development (testing) have been skipped because of the epidemic emergency.’ as false (OR: 2.36; 95% CI: 1.73–3.22).

Conclusion
The results suggest that social conformism and confidence in systems are distinct antecedents of vaccination among healthcare and welfare workers, which should be taken into account in vaccine promotion.
Medikal ve Endüstriyel Açıdan Kannabinoidlerin Önemi ve Türkiye Ekonomisine Katkı Potansiyeli
Authors: GÖKGÖZ Azize , YILMAZ CAN Emine 
Published: April 2022

Kenevir bitkisi, endüstri ve tıp gibi temel alanlarda kolay, ekonomik ve sağlıklı çözümler sunan bir
bitkidir. Başta kannabinoidler olmak üzere çok sayıda kimyasal madde içermektedir ve zengin bir ürün
yelpazesi vardır. Endüstriyel kenevir biyobozunur her çeşit plastik madde, kağıt-karton, ısı yalıtım ve
inşaat malzemeleri üretiminde, tekstil ve otomotiv sektöründe, gıda ve kozmetik ürünlerin imalatında
ve biyodizel üretiminde kullanılmaktadır. Medikal kenevir kemoterapiye bağlı bulantı-kusma, kanser ile
ilişkili nöropatik ağrı, multipl skleroz ile ilişkili spastisitede, HIV’li hastalarda kilo alımında ve epilepsi gibi
bazı hastalıkların tedavisinde kullanılmaktadır.
Bu yazıda, eski uygarlıklar tarafından kullanılmış olup kültürümüzde önemli bir yere sahip olan ve son
yıllarda popülerlik kazanan tıbbi ve endüstriyel kenevir bitkisinin dünden bugüne kullanımı, yetiştirilmesi,
tıp ve endüstrideki yeri hakkında bilgi verilmesi ve aynı zamanda kenevirin ekonomik potansiyelinin
ortaya koyulması amaçlanmıştır.
El-Ayak ve Ağız Hastalığında Ortalama Trombosit Hacmi Değişir mi?
Authors: KARACI Mehmet 
Published: April 2022

Amaç: El-ayak-ağız hastalığı (EAAH); ateş, deri ve mukoza lezyonları ile seyreden, çocukluk çağının
enteroviral döküntülü bir hastalığıdır. Ortalama trombosit hacmi (MPV) trombosit fonksiyonu ile ilişkilidir
ve çeşitli bozukluklarda klinik ilginin bir göstergesi olarak trombosit sayısından daha hassas bir
indeks olabilir. Biz bu çalışmada; EAAH‘da MPV seviyeleri, değişir mi ve onikomedozis gibi sonradan
gelişebilecek bulguları önceden saptamada yol gösterici olabilir mi sorularına cevap aramaya çalıştık.
Gereç ve Yöntemler: Hastanemiz Çocuk Sağlığı ve Hastalıkları Bölümüne 2018-2019 yılları arasında
başvurup klinik olarak EAAH’ı tanısı alan 52 hasta çocuk ve 48 sağlıklı kontrollerin geriye dönük olarak
demografik verileri, şikayetleri ve fizik muayene bulguları ve tam kan sayımı parametreleri değerlendirildi.
Bulgular: Hastaların ortalama yaşları 3,3 ±2,5 yıl, kontrol grupta ise 3,2 ± 2,6 yıldı. Hastaların %59,6
erkek, %40,4’ü kız idi. Gruplar arasında yaş ve cinsiyet olarak bir farklılık saptanmadı. Hastaların en sık
Mayıs- Haziran aylarında başvurduğu (%63,6) görüldü. En sık başvuru şikayeti döküntü (%100), oral
aft (%80,7) ve ateş (%76,9) idi. Hastaların dördü (%7,6) çeşitli nedenlerle yatırılarak tedavi edildi. Tam
kan incelemesi yapılan hastaların ortalama lökosit değeri 10459±3485/mm3 iken bu oran sağlıklı grupta
6900±2175/mm3 (p=0,019) idi. Hasta ve kontrol grubunda sırayla ortalama MPV değeri 7,02±1,49 fL,
ve 8,1±1,2 fL (p=0.001) idi. Hasta grubunda tırnak bulguları gelişenlerle gelişmeyenler arasında yaş,
cinsiyet tanı ayı ve MPV değerleri arasında bir fark saptanmadı (p=0.36).
Sonuç: Özellikle MPV değeri kontrol grubuna göre anlamlı düşük saptanmıştır. Bundan dolayı özellikle
döküntüsü henüz ortaya çıkmamış olan ve arada kalınan hastaları erken öngörmede bu değerin de
kullanılabileceğini düşünmekteyiz.
Amatör Badminton Oyuncularının Vücut Kompozisyonlarının Sportif Performansa Etkisi: Zonguldak Bölge Şampiyonası
Authors: BOSTAN Geylan , KUDAK Hüseyin Hakan , GÜMÜŞ Mustafa 
Published: April 2022

Amaç: Araştırmanın amacı amatör genç badminton oyuncularının vücut kompozisyonu ile sportif
performansları arasındaki ilişkiyi incelemektir.
Gereç ve Yöntemler: Çalışma 90 sporcu ile gerçekleştirildi. Sporcuların ölçümleri müsabakalar
başlamadan Tanita BC-418 Segmental Vücut Analiz Tartısı ile ölçüldü. Araştırmada toplanan verilerin
analizi için SPSS 21.0 programından yararlanılmıştır. Araştırmaya katılan sporcuların kendi aralarındaki
badminton müsabaka sonuçlarına göre elde ettikleri dereceler incelenmiştir. Ayrıca tüm sporcuların
genel vücut ölçümleri, bacak, kol ve gövdelerinde yağ yüzdesi, yağsız vücut ağırlığı ölçümleri yapılmıştır.
Öncelikle sporcuların cinsiyetlerine göre boy, ağırlık ve beden kütle indekslerine bakılmıştır. Daha sonra
cinsiyete göre haftalık antrenman saatleri ve antrenman yılları karşılaştırılmıştır.
Bulgular: Araştırmaya katılan sporcuların %48,9’u kadın, %51,1’i erkektir. Araştırmada 10 farklı ilden
kulüplerin sporcuları yer almış olup en az sporcu Karabük ilinden katılmıştır. Sporcuların beden kütle
indekslerine bakıldığında %35,6’sı zayıf grupta, %53,3’ü normal ağırlıkta ve %11,1’in ise fazla ağırlıkta
olduğu görülmektedir.
Sonuç: Elde edilen veriler göre, kadınların toplam vücut yağ yüzdeleri x=26,31 iken erkeklerin yağ
yüzdeleri x=18,93 olarak görülmüştür. Kadınların toplam vücut yağ ağırlıkları x=13,57 iken erkeklerin
yağ ağırlıkları x=8,99 olarak görülmüştür. Gruplar arasında ortaya çıkan bu farklar istatistiksel olarak
anlamlı görülmüştür (p
Zonguldak Bülent Ecevit Üniversitesi Tıp Fakültesi 2020-2021 Eğitim Yılı Dönem 3 Öğrencileri Kanıta Dayalı Tıp Çalışmaları Özetleri
Authors: TOPALOĞLU Ömercan , AYOĞLU Ferruh Niyazi , AYDEMİR Hande , CAN Murat , BAYRAKTAROĞLU Taner 
Published: April 2022

Amaç: Kanıta dayalı tıp uygulamaları gerçek bilgiye en güvenilir şekilde ulaşmak, bilimsel aynı zamanda eleştirel düşünceyi
geliştirmek açısından önemlidir. Tıpta yeni bilgilere gereksinim, kanıta dayalı tıp uygulamalarının yaygınlaşmasına neden
olmaktadır. Sürekli tıp eğitimi de kanıta dayalı tıbbın önemli bir parçası olarak kabul edilmektedir. Fakültemizdeki kanıta
dayalı tıp uygulamalarının amacı, tıp fakültesi öğrencilerine kanıta dayalı tıbbın önemini kavratmak, bilimsel bir çalışmanın
içinde yer almalarını sağlamak ve bu çalışma basamaklarını öğretmektir
Gereç ve Yöntemler: Kanıta dayalı tıp kapsamında yapılan çalışmalar, Tıp Fakültesi Dönem 3 öğrencileri tarafından yürütülmektedir.
Dersin sorumlu öğretim üyesi tarafından gruplara ayrılırlar. Her bir grup için de sorumlu araştırmacı öğretim üyesi
belirlenir. Ders programında belirlenen tarihlerde öğrenciler bir araya gelip araştırma konusunun başlığını kesinleştirir. Etik
kurul formu hazırlanıp etik kurula başvuru yapılır. Çalışma sonlandıktan sonra da özet/makale hâline getirilir ve özet hâline
getirilen çalışmalar sunulur ve tartışılır.
Bulgular: 2020-2021 Eğitim ve Öğretim döneminde gerçekleştirilen kanıta dayalı tıp kapsamında 194 sayıda Dönem 3
öğrencisi çalıştı. COVID-19 pandemisinin etkileri ve aşı üzerine olan çalışmalar başta olmak üzere; kanser, uyku, güneşin
zararları, yeni sosyal hayat ve cinsel mitler gibi güncel konularda sorumlu öğretim üyesi gözetiminde toplam 15 farklı çalışma
yapıldı. Bu çalışmaların başlıkları ve sorumlu öğretim üyeleri Tablo-1 de yer almaktadır. Hazırlanan özetler dijital platform
üzerinden sunuldu ve tartışıldı.
Sonuç: Tüm Dönem 3 öğrencileri, COVID-19 pandemisinden dolayı uzaktan eğitim aldıkları 2020-2021 Eğitim ve Öğretim
döneminde çevrimiçi öğrenme ortamlarında bilimsel bir çalışmanın tüm aşamalarını yürüttüler ve çalışmalarını başarıyla
sonlandırdılar.
THE IMPACT OF ROBOTICS CODING AND 3D PRINTING STEM ACTIVITY ON 21ST CENTURY LEARNER SKILLS OF TEACHER CANDIDATES
Authors: Güleryüz Hasan , Dilber Refik 
Published: April 2022

STEM education focusing on students' 21st century skills aims to increase interest in engineering fields such as 3D printing and robotics coding, which have an important place in the future education system. The aim of this study is to examine the effect of 3D printing and robotics coding STEM activities on the 21st century learner skills of teacher candidates and its sub dimensions (Cognitive, Autonomous, Collaboration and Flexibility, and Innovativeness). 37 science teacher candidates participated in the study which lasted 13 weeks. In this study, mixed research method was used. Quantitative data was obtained through 21st Century Learner Skills Use Scale and qualitative data was taken from the field notes and semi-structured interview. According to the study's findings, teacher candidates used the 21st century learner skills and its sub dimensions at an advanced level. Within the scope of the study, 3D printing and robotics coding trainings were given to science teacher candidates within the scope of STEM education and activities were made within the scope of these trainings. Four activities were done for 3D printing and three activities for robotics coding. Out of 3D printer programs, 3D Builder and Zaxe (destop) PLA were taught. Arduino IDE and Fritzing for circuit diagram from robotic coding programs were taught. With 3D printing and robotics coding STEM activities, teacher candidates improved 21.st century skills such as critical thinking, collaborating, communicating, productivity and creativity. In addition, they have a positive attitude towards science, technology, engineering and mathematics.
The Implementation of MQTT Protocol using PT-100 for Monitoring the Vaccine Temperature
Authors: Pramono Sigit , Slamet Indriyanto  , Wahyu Junianto  
Published: April 2022

A vaccine has an essential role for humans because it can reduce the effect of organism infection and activate the body's immune. The limitation of temperature when the vaccine is stored becomes one of the influential factors for its quality. Since the recent technique used for checking the temperature is manual, the process of real-time temperature monitoring cannot be done and becomes the main problem in the process of storing vaccines. This research is aimed to develop a system for measuring temperature on a chiller through a temperature sensor and the internet of things automatically. The methods used in the MQTT protocol are published and subscribed. The quality of service (QoS) to measure network capability and PT-100 is the sensor in this research because it has a high accuracy level, linear signal change, and fast response. This sensor can measure glycol liquid with a temperature range of 2-8°C. Data distribution uses an ESP module to connect the data to Antares through the wifi network. The temperature value measurement using PT-100 toward vaccine chiller temperature obtains an accuracy value of 99,32%. This accuracy value shows that the result is compatible with the logger data measurement tool development used with an error result of 0.58%. Delay parameter testing on the QoS level obtains the average value of 41.91 ms, while the Packet loss parameter obtains the value of 0%.