bluuebunny/crossref_metadata_2025_split huggingface dataset:
High‐Voltage, Highly Reversible Sodium Batteries Enabled by Fluorine‐Rich Electrode/Electrolyte Interphases
Authors: Guo Xu‐Feng , Yang Zhuo , Zhu Yan‐Fang , Liu Xiao‐Hao , He Xiang‐Xi , Li Li , Qiao Yun , Chou Shu‐Lei 
Published: April 2022

AbstractHigh energy density and long‐term cycling stability are crucial factors for the commercialization of sodium batteries in large scale. In this regard, cathode materials that can operate at high voltage have attracted great interest owing to their high energy density. However, traditional electrolytes cannot be used in high‐voltage sodium batteries due to their limited oxidative stability. Therefore, there is a great challenge to develop appropriate electrolytes for high‐voltage cathode materials. Herein, a diluted fluoroethylene carbonate (FEC)‐based electrolyte (1 m NaPF6 in FEC/DMC = 2/8 by volume) is designed for Na4Co3(PO4)2P2O7 (NCPP) cathode with a high operation voltage of 4.7 V to achieve superior electrochemical performance with a capacity retention of 90.10% after 500 cycles at 0.5 C and capacity retention of 89.99% after 1000 cycles at 1 C. The excellent electrochemical performance of the NCPP||Na cells can be attributed to the formation of inorganic and robust NaF‐rich cathode electrolyte interphase and F‐rich solid electrolyte interface on high voltage NCPP cathode and Na metal anode, respectively. This work points out a very promising strategy to develop high‐voltage sodium batteries toward practical applications.
Aptamer‐Functionalized Barcodes in Herringbone Microfluidics for Multiple Detection of Exosomes
Authors: Chen Hanxu , Bian Feika , Guo Jiahui , Zhao Yuanjin 
Published: April 2022

AbstractTumor‐derived exosomes are vital for clinical dynamic and accurate tumor diagnosis, thus developing sensitive and multiple exosomes detection technology has attracted remarkable attention of scientists. Here, a novel herringbone microfluidic device with aptamer‐functionalized barcodes integration for specific capture and multiple detection of tumor‐derived exosomes is presented. The barcodes with core–shell constructions are obtained by partially replicating the periodically ordered hexagonal close‐packaged colloidal crystal beads. As their inverse opal hydrogel shell possesses rich interconnected pores, the barcodes could provide abundant surface area for functionalization of DNA aptamers to realize specific recognition of target exosomes. Besides, the encoded structure colors of the barcodes can be maintained stably during the detection events as their hardish cores are with sufficient mechanical strength. It is demonstrated that by embedding these barcodes in herringbone groove microfluidic device with designed patterns, the specific capture efficiency and synergetic detection of multiple tumor‐derived exosomes in peripheral blood can be significantly improved due to enhanced resistance of turbulent flow. These features make the aptamer‐functionalized barcodes and herringbone microfluidics integrated platform promising for exosomes extraction and dynamic tumor diagnosis.
An experimental study on strength and durability characteristics of self‐curing self‐compacting concrete
Authors: Dey Subhashish , Kumar Vemu Venkata Praveen , Phani Manoj Akula Venkata 
Published: April 2022

AbstractThe present study is focused on the compressive strength, water retention, and workability by varying the percentage of poly ethylene glycol 200 and liquid paraffin wax from 0% to 1% by weight of cement for self‐compacting concrete and compares it with conventional SCC. Percentages of 0.1%, 0.5%, and 1% (in proportion to the weight of cement) were adopted in the study. The comparison was done in a grade concrete and with cases such as indoor curing and water‐based curing. Slump‐flow test and V‐funnel tests were carried out on the fresh concrete to evaluate the workability of concrete. Concrete weight loss with time is evaluated to determine the water retention capacity. Compressive strength of cube specimens was conducted at the end of 7 and 28 days of curing. The durability of the concrete was assessed by immersing the concrete specimens in acids. The fresh properties were satisfied according to EFNARC specifications. Based on the weight loss percentage and satisfaction of compressive strength, the dosage of a self‐curing compound was determined. XRD analysis of the concrete was also performed on the concrete specimens.
Regulating closed pore structure enables significantly improved sodium storage for hard carbon pyrolyzing at relatively low temperature
Authors: Zhou Siyu , Tang Zheng , Pan Zhiyi , Huang Yuancheng , Zhao Le , Zhang Xi , Sun Dan , Tang Yougen , Dhmees Abdelghaffar S. , Wang Haiyan 
Published: April 2022

AbstractThe closed pore has been considered as the key structure for Na ion storage in hard carbon. However, the traditional view is that closed pores can only be formed by the curling of graphite‐like crystallites in the case of high temperature carbonization. Ingenious designing of closed pore structures at lower temperature is still blank. Herein, for the first time, engineering the wall thickness and number of closed pores in waste rosewood‐derived hard carbon was successfully achieved at a low temperature of 1100°C by removing the lignin and hemicellulose components in wood precursor. When applied as an anode material, the optimum sample exhibits a high capacity of 326 mAh/g at 20 mA/g and a remarkable rate capability of 230 mAh/g at 5000 mA/g, significantly higher than those of the untreated sample (only 33 mAh/g at 5000 mA/g). The significantly improved Na storage performance should be attributed to abundant closed pores that provide sufficient spaces for Na storage and thin pore wall structure that is beneficial to the diffusion of Na+ in the bulk phase. This work provides a new idea for the future application of biomass‐based hard carbon for advanced Na ion batteries.
Transnational Mexican Youth Negotiating Languages, Identities, and Cultures Online: A Chronotopic Lens
Authors: Lam Wan Shun Eva , Christiansen Martha Sidury 
Published: April 2022

AbstractThis article presents a case study with two transnational Mexican youth that came from a larger study of the digital media practices of young people in an urban high school. Our study takes a chronotopic (Bakhtin, 1981) lens to understand the youths' accounts of their digital communication. Analysis of interviews and observations with the youth when they described their online activities show that the youth employed digital literacies to vicariously “live” experiences and keep up with life away from their families in Mexico. The youth situated their activities in three distinct but dialogical chronotopes (family, hometown, and transborder) to create transnational connections and make sense of who they are. They drew on digital artifacts to narrate themselves, developed familial, cultural, and political knowledge, and expanded their linguistic repertoires in the process. The findings have implications for TESOL classrooms that seek to build on the border‐crossing experiences and linguistic and multimodal resources of young people in their learning. We discuss how youths' digital practices and embedded artifacts serve to construct multiple contexts and vantage points for developing their transnational identities and knowledge, and how these practices could be recognized as agentic forms of narrative production and learning in the classroom.
Scholars, Printers, and the Sphere: New Evidence for the Challenging Production of Academic Books in Wittenberg, 1531–1550
Authors: Limbach Saskia 
Published: April 2022

AbstractThis chapter introduces those printers and publishers who were involved in the process and considers the economics of the local print industry, which was, at the time, the fastest-growing in the entire Holy Roman Empire. By analyzing the university’s interactions with book producers, especially with respect to Melanchthon’s letters, which reveal his close ties to the book industry, I argue that even in this dominant center of printing, the relationship between academics and printers/publishers could be rather fraught; authors and editors even referred to the producers of their books as “beasts,” “harpies,” and “men of iron.” Drawing on hitherto unexplored sources, I also shed light on the prices of academic books, their print runs, and the reuse of illustrations in different editions. Finally, I establish how students in sixteenth-century Wittenberg could obtain academic books for their studies and how expensive the Sphaera was in comparison to other books and commodities.
Sacrobosco at the Book Fairs, 1576–1624: The Pedagogical Marketplace
Authors: Maclean Ian 
Published: April 2022

AbstractBetween 1576 and 1624, there were at least twenty declarations of Latin editions of theDe sphaeraand one of Francesco Pifferi’s Italian-language version in the Frankfurt Book Fair Catalogues. These declarations are not straightforward. Some are editions, and some are reissues; some are associated with the names not of the publisher but of the bookstore through where they were on offer. In some cases, the year of declaration and the place of publication are misleading, and, in the case of the Christophorus Clavius commentaries, the claim made about the number of the edition (whether third, fourth, fifth, or “seventh”) is false. The aim of this paper is to elucidate how the fairs operated, to identify which edition is in question, to place these in the context of the Catholic, Lutheran, and Reformed pedagogy of the period, and to show how producers, advertisers, and commissioning agents of the SacroboscoSphaeraeditions interacted, with special reference to the editions of Rome and Venice (and their publishers the Basa family and Giovanni Battista Ciotti), and those of Lyon and St. Gervais (and their publishers de Gabiano and Samuel Crespin). The final case considered is the declaration in 1624 of the edition of the Jesuit Bernardus Morisanus produced by the Reformed printer-publisher Peter Mareschal, as an element in acursus philosophicus.
The Giunta’s Publishing and Distributing Network and Their Supply to the European Academic Market
Authors: Ottone Andrea 
Published: April 2022

AbstractThis essay presents the Giunta publishing firm as a transnational network, highlighting its ideal center and peripheries. It describes the construction of a business model in conjunction with marketing channels and a consequent publishing plan intended to enhance the firm’s reputation in a specific slice of the book market: the clergy and the high professions. At the center of this narrative are several instances of the Giunta endeavoring to commercialize Sacrobosco’s Sphaera. I argue that, regardless of the eight known instances in which the Giunta family published Sacrobosco, the Tractatus de sphaera remained of marginal interest in the general publishing plan laid down by the firm.
Advanced Powertrain Systems for Platooning-Capable Trucks
Authors: Nöst Michael , Doppler Christian , Mladek Alexander 
Published: April 2022

AbstractThis chapter deals with the interaction of platooning-capable trucks and their powertrain systems. In a first step, prospective propulsion systems and their characteristics for platooning are discussed. Therefore, different topologies are analysed, also in terms of the intended use cases. These considerations are made mainly according to CO$$_{2}$$

2

-limitation efforts in the background. Secondly, thermal management regarding platooning is in the focus. Investigations on the influence of the air mass flow for an internal combustion engine (ICE) operated truck are presented. Further, thermal management challenges in combination with a fuel cell operated truck are discussed. For this purpose, dedicated solutions and methods in development are presented. Finally, essential future research fields are outlined.
How Platooning Research Enhances the European Innovation System
Authors: Bäumler Ilja , Kotzab Herbert , Aigner Walter 
Published: April 2022

AbstractMaybe we would need a convincing narrative how innovation and our innovation system contribute to societal wealth—a new kind of Adam Smith equivalent. European road transport is part of a wider ecosystem where significantly increasing levels of digitalisation, automation and innovation will re-shape the world as we have known it. Ambitious political agendas to enhance sustainability and to increase transport effectiveness beyond what can be achieved within a fragmented and traditional way of operation have added momentum. Nevertheless, there are significant open issues beyond what road-maps to various futures maintain to know. Management narratives related to innovation and innovation systems have been challenged. This chapter intends to outline some of the elements how this kind of C-ITS-related platooning research has enhanced our shaping and re-framing of new questions and concepts regarding the European innovation system. Even without electronically coupled trucks on European public roads, elements of dynamic capabilities have evolved. On the other hand, it has become obvious how far some stakeholders have fallen behind the knowledge generation in European C-ITS-related projects. By means of rather selective knowledge intake and knowledge-related search paths, some institutions have shown to be some fifteen years behind accessible knowledge.
Truck Platooning Worldwide
Authors: Atasayar Hatun , Blass Philipp , Kaiser Susanne 
Published: April 2022

AbstractAlthough early attempts date back several decades, truck platooning initiatives and trials gained significant momentum in the 2010s in the light of the overall wave of vehicle automation. This chapter aims at providing an overview of the most significant platooning endeavours over the past two decades, with focus on European efforts and their thematic priorities and conclusions. Whereas for example relevant Southeast Asian countries tend to be driven by national roadmaps and national funding, many of the European projects and trials are funded by the European Commission’s research programmes, bringing together several countries and resulting in more open access information. The presented review demonstrates how the focus of the discussion changed over time, also revealing a shift in the relevant parties and stakeholders: while the initial intention was reduction in fuel costs, the claimed benefits have now diversified and additional interest groups brought to the table environmental, safety, legal, infrastructural and labour regulation arguments for and against platooning.
Towards Truck Platooning Deployment Requirements
Authors: Neubauer Matthias , Schildorfer Wolfgang 
Published: April 2022

AbstractTruck platooning represents a promising means to enhance efficiency of freight transport. Developments of truck platooning date back to the early 1990s, starting with projects to illustrate the technical feasibility followed by projects investigating the potential of fuel savings up to feasible business models and multi-brand and multi-fleet platooning approaches. However, the deployment and adoption of truck platooning technologies need to detail, harmonise and finally meet diverse requirements. Figure 3.1 sketches requirement dimensions related to truck platooning, which span from safety and security requirements, stakeholder requirements to technical and functional requirements. In this chapter, selected results addressing requirements related to energy-efficient truck platooning, user and other road user requirements, road safety requirements and technical requirements related to C-ITS are presented.
Evaluation of Infiltrative Cardiomyopathies
Authors: Di Carli Marcelo F. , Singh V. , Divakaran S. , Cuddy S. , Dorbala S. , Giubbini Raffaele , Dondi Maurizio 
Published: April 2022

AbstractInfiltrative cardiomyopathies are a group of disorders characterized by the abnormal deposition of proteins and/or inflammatory cells leading to cardiac dysfunction and electrical disorders. This chapter will illustrate the role of PET/CT in cardiac sarcoidosis and amyloidosis, and the complementary role of PET/MR and 99mTc PYP SPECT.
The Peace Policy Maker: Dan Smith
Authors:   Interviewed by Stein Tønnesson
Published: April 2022

Abstract“What I want, if you look at me and my career, is on the one hand, a lot of activism and on the other, a lot of research.” In this interview, Dan Smith (b. 1951) recalls how a student of English literature became the leader of two activist organizations, the Campaign for Nuclear Disarmament and International Alert, and two peace research institutes, PRIO and SIPRI (Stockholm International Peace Research Institute).
A Historian’s Paths to Peace
Authors:   Essay by Stein Tønnesson
Published: April 2022

AbstractIn this essay, the peace historian and former PRIO director Stein Tønnesson (b. 1953) goes through the nine paths he has explored in his quest to understand war and peace: War as war, war as horror, outbreaks of war, severity of wars, war endings, peace viability, regional transitions to peace, peace practices, and peaceful utopian moments. He claims to have mostly shied away from a tenth path: Major peaceful utopias, such as a classless or harmonious society.
Congo and Structural Violence: Helge Hveem
Authors:   Interviewed by Per Olav Reinton
Published: April 2022

Abstract“It was a significant day for me when … doctor Denis Mukwege received the Nobel Peace Prize in 2018.” In this interview, Helge Hveem (b. 1941) recounts how his stay in the Democratic Republic of Congo in the 1960s put him on a path towards the kind of theory-driven, policy-oriented empirical research he later pursued at PRIO and the University of Oslo. His research has exposed the exploitative practices of transnational companies.
Higher education expansion and gender norms: evidence from China
Authors: Si Wei 
Published: April 2022

AbstractThis paper explores whether the expansion of higher education can influence attitudes regarding gender norms. I evaluate the impact of China’s higher education expansion since 1999. The results show that the reform has significantly increased higher educational attainment for both women and men. However, women’s progressive views on gender roles are negatively affected following the expansion. The erosion of women’s egalitarian ideology can be attributed to the findings that women’s opportunities in the labor market are worsening relative to those of men. The results are significantly driven by married women and people who live in areas with a high male-to-female sex ratio. Practical conditions in the labor market and at home may adversely affect women’s ability to fulfill egalitarian gender roles.
Effects of heroin self-administration and forced withdrawal on the expression of genes related to the mTOR network in the basolateral complex of the amygdala of male Lewis rats
Authors: Ucha Marcos , Roura-Martínez David , Santos-Toscano Raquel , Capellán Roberto , Ambrosio Emilio , Higuera-Matas Alejandro 
Published: April 2022

Abstract
Rationale
The development of substance use disorders involves long-lasting adaptations in specific brain areas that result in an elevated risk of relapse. Some of these adaptations are regulated by the mTOR network, a signalling system that integrates extracellular and intracellular stimuli and modulates several processes related to plasticity. While the role of the mTOR network in cocaine- and alcohol-related disorders is well established, little is known about its participation in opiate use disorders.

Objectives
To use a heroin self-administration and a withdrawal protocol that induce incubation of heroin-seeking in male rats and study the associated effects on the expression of several genes related to the mTOR system and, in the specific case of Rictor, its respective translated protein and phosphorylation.

Results
We found that heroin self-administration elicited an increase in the expression of the genes Igf1r, Igf2r, Akt2 and Gsk3a in the basolateral complex of the amygdala, which was not as evident at 30 days of withdrawal. We also found an increase in the expression of Rictor (a protein of the mTOR complex 2) after heroin self-administration compared to the saline group, which was occluded at the 30-day withdrawal period. The activation levels of Rictor, measured by the phosphorylation rate, were also reduced after heroin self-administration, an effect that seemed more apparent in the protracted withdrawal group.

Conclusions
These results suggest that heroin self-administration under extended access conditions modifies the expression profile of activators and components of the mTOR complexes and show a putative irresponsive mTOR complex 2 after withdrawal from heroin use.
Comparison of docetaxel pharmacokinetics between castration-resistant and hormone-sensitive metastatic prostate cancer patients
Authors: Vermunt Marit A. C. , van Nuland Merel , van der Heijden Lisa T. , Rosing Hilde , Beijnen Jos. H. , Bergman Andries M. 
Published: April 2022

Abstract
Purpose
Recently, docetaxel treatment of metastatic prostate cancer patients shifted towards the hormone-sensitive stage of the disease. There are contradictive reports on differences in toxicity of docetaxel in metastatic hormone-sensitive prostate cancer (mHSPC) and metastatic castration-resistant prostate cancer (mCRPC) patients. Possible differences in toxicity might be attributed to different pharmacokinetics (PK) in the two patient populations.

Methods
Patients with mCRPC or mHSPC and a standard indication for docetaxel treatment were included in the study. All patients had suppressed serum testosterone levels (≤ 0.5 ng/mL or 1.73 nmol/L). Venous blood samples were obtained at the first docetaxel treatment, until 48 h after infusion. Plasma concentrations of docetaxel, unbound docetaxel and docetaxel metabolites were measured using validated liquid chromatography coupled tandem mass spectrometry (LC–MS/MS) assays and compared between the two groups. Moreover, serum levels of docetaxel transporting α1-acid glycoprotein were measured and docetaxel toxicity recorded.

Results
A total of ten mCRPC and nine mHSPC patients were included in the study. The two cohorts differed in the number of prior treatments and opiate use, which were higher for mCRPC patients. The docetaxel PK was not different between mCRPC and mHSPC patients, with areas under the plasma concentration versus time curve (AUC0-48) 1710 [coefficient of variation (CV) 28.4%] and 1486 (CV 25.2%) ng/mL*h (p = 0.27), respectively. Also, the PK profile of unbound docetaxel, M1/M3, M2 and M4 metabolites were similar in both groups. Docetaxel doses were reduced in 50% of the mCRPC patients and 11% of the mHSPC patients.

Conclusion
The PK profile of docetaxel was similar in mCPRC and mHSPC patients. Therefore, possible differences in toxicity between mCRPC and mHSPC patients cannot be explained by differences in docetaxel PK in our study population. These results suggest that treatment adaptations are not recommended in the new population of patients with mHSPC.
Narcolepsy: a model interaction between immune system, nervous system, and sleep-wake regulation
Authors: Latorre Daniela , Sallusto Federica , Bassetti Claudio L. A. , Kallweit Ulf 
Published: April 2022

AbstractNarcolepsy is a rare chronic neurological disorder characterized by an irresistible excessive daytime sleepiness and cataplexy. The disease is considered to be the result of the selective disruption of neuronal cells in the lateral hypothalamus expressing the neuropeptide hypocretin, which controls the sleep-wake cycle. Diagnosis and management of narcolepsy represent still a substantial medical challenge due to the large heterogeneity in the clinical manifestation of the disease as well as to the lack of understanding of the underlying pathophysiological mechanisms. However, significant advances have been made in the last years, thus opening new perspective in the field. This review describes the current knowledge of clinical presentation and pathology of narcolepsy as well as the existing diagnostic criteria and therapeutic intervention for the disease management. Recent evidence on the potential immune-mediated mechanisms that may underpin the disease establishment and progression are also highlighted.