bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diversity and dynamics of bacterial communities in the drinking water distribution network of a mid-sized city in Brazil
Authors: Batista Ana Maria Moreira , Siqueira Juliano Curi de , Meynet Paola , Werner David , Garcia Graziella Patricio Pereira , Davenport Russell J. , Pereira Alyne Duarte , Siniscalchi Luciene Alves Batista , Araújo Juliana Calábria de , Mota Filho Cesar Rossas 
Published: November 2022

Abstract
This study assessed the bacterial community composition of a drinking water system (DWS) serving a mid-sized city (120,000 inhabitants) in Brazil. Water samples, including raw and treated water, were collected at seven points throughout the DWS. DNA was extracted and analysed using high-throughput sequencing (Ion Torrent). Free chlorine and turbidity were measured in situ. Results showed that the highest relative abundance of 16S rRNA genes was from phyla Proteobacteria, followed by Bacteroidetes and Actinobacteria. The next most abundant phylum was Cyanobacteria, represented by Arthronema, Calothrix, and Synechococcus. An interesting observation was that the DNA-based analysis suggested a bacterial community change in the distribution network, with treated reservoir water being very different from the network samples. This suggests active microbiology within the distribution network and a tendency for bacterial diversity to decrease after chlorine disinfection but increase after pipeline distribution. In raw water, a predominance of Proteobacteria was observed with reduced Cyanobacteria, showing a negative correlation. In treated water, Proteobacteria were negatively correlated with Bacteroidetes. Finally, 16S rRNA genes from Firmicutes (especially Staphylococcus) had a high abundance in the chlorinated water, which may indicate the phylum's resistance to chlorine residuals. Opportunistic pathogens, e.g., Mycobacteria, Legionella, and Staphylococcus, were also observed.
Neoliberalismo e o trabalho dos enfermeiros
Authors: Cardoso Thereza Christina dos Santos Figueira , Santos Ronan dos , Souza Mônica Oliveira da Silva e , Tonole Renato , Passos Joanir Pereira 
Published: November 2022

Trata-se de um artigo de reflexão que se propôs a discutir as modificações impostas ao trabalho de enfermeiros, tendo como cerne as mudanças ocorridas a partir da década de 1990 com a adoção da doutrina socioeconômica neoliberal. Há diminuição gradativa, porém, significativa da intervenção do Estado em diversos setores, especialmente na saúde, assistimos o avanço de entidades privadas para gestão dos serviços públicos. Para a carreira de profissionais enfermeiros essa condição trouxe um grande impacto, com redução dos quadros de servidores de carreira, diminuição de editais de concursos, contratações frágeis, desrespeito aos direitos trabalhistas, condições que se traduzem em insegurança e instabilidade para os profissionais de forma ampla, prejudicando a gestão no planejamento de suas ações trazendo incerteza aos enfermeiros quanto a permanência no vínculo. A partir de estudos é possível correlacionar a adoção do modelo neoliberal e a crescente precarização do trabalho dos enfermeiros. A temática em questão, aponta ainda a necessidade de introduzir a discussão dos aspectos que envolvem nosso mundo do trabalho desde o período de formação dos futuros profissionais.
Palavras-Chave: Precarização; Enfermeiro; Trabalho.
PENGEMBANGAN BAHAN AJAR SAINS BERBASIS STEM UNTUK PENINGKATAN KETERAMPILAN BERPIKIR TINGKAT TINGGI (HOTS) PURWARUPA KAPAL BOAT
Authors: Ngadinem Ngadinem 
Published: November 2022

Penelitian ini bertujuan mendeskripsikan validitas dan keterampilan berpikir tingkat tinggi (HOTS) peserta didik terhadap pengembangkan bahan ajar sains purwarupa kapal boat dalam bentuk perangkat pembelajaran Fisika pada pokok bahasan penerapan hukum III Newton dan hukum kekekalan momentum berbasis STEM dengan model pembelajaran PjBL (project best learning) untuk siswa SMA/MA kelas X. Penelitian ini menggunakan metode penelitian dan pengembangan (Research Development) dengan model pengembangan ADDIE yang terdiri atas lima tahapan, yaitu analysis, design, development, implementation, dan evaluation. Penelitian ini menggunakan teknik analisis deskriptif, dengan cara menghitung persentase nilai hasil validasi. Untuk keterampilan berpikir tingkat tinggi (HOTS) digunakan instrumen soal penilaian HOTS. Untuk respon peserta didik digunakan instrumen penilaian diri. Perangkat pembelajaran telah melalui tahap uji validasi oleh ahli materi dengan persentase rata-rata 92,44% (kriteria layak) dan oleh ahli media sebesar 93,54% (kriteria layak), sehingga bahan ajar itu layak digunakan sebagai perangkat pembelajaran di kelas. Hasil persentase rata-rata respon siswa 76,54%, hasil rata-rata keterampilan berpikir tingkat tinggi (HOTS) sebelum dan sesudah menggunakan bahan ajar 52,58% dan 73,64%. Karena ada kenaikan dari hasil sebelum dan sesudah menggunakan bahan ajar, maka bahan ajar sains berbasis STEM purwarupa kapal boat yang dikembangkan dengan model pembelajaran PjBL dapat meningkatkan keterampilan berpikir tingkat tinggi peserta didik. Kata Kunci: pengembangan, bahan ajar sains, STEM model PjBL, purwarupa kapal boat, HOTS
Recorridos óptimos para la recolección de residuos tecnológicos
Authors: Pérez Diana , Villagra Andrea , Pandolfi Daniel 
Published: November 2022

El aumento progresivo en la generación de residuos de equipos eléctricos y electrónicos es proporcional a la evolución de la tecnología, esto conlleva implicaciones ambientales negativas. Las actividades en la recolección de residuos se pueden agrupar en cinco etapas correspondientes al ciclo de vida de los residuos: generación, recolección y transporte, transformación, tratamiento y eliminación final. El costo de la recolección y transporte es un factor crítico en el gasto fiscal de los sistemas de gestión de residuos, por esta razón las mejoras en este campo representan un importante papel en el ahorro del gasto de las organizaciones encargadas de esta tarea. En este trabajo se aplican a instancias reales de las ciudades de Caleta Olivia y Comodoro Rivadavia el algoritmo de Optimización basado en colonia de hormigas (ACO), se lo compara con resultados obtenidos por expertos. Los resultados demuestran la bondad del algoritmo propuesto logrando una reducción en los kilómetros necesarios para realizar los recorridos. Además, se analiza la recuperación de metales utilizando las soluciones obtenidas por ACO y la reducción en la emisión de gases efecto invernadero.
El cuidado en las alteraciones respiratorias en contexto de pandemia en un Hogar de Personas adultas mayores. Rio Gallegos
Authors: Oyarzo Saldivia Roxana Katherina , Ojeda Sara , Ivanissevich María Laura 
Published: November 2022

En el marco de una beca de investigación para alumnos avanzado de la Licenciatura en Enfermería se realizó un estudio con el propósito de identificar la existencia de alteraciones respiratorias en personas adultas mayores en un Hogar de residencia permanente de la ciudad de Rio Gallegos y describir los tipos de cuidados pertinentes que reciben. El contexto de pandemia por Covid-19 alteró el acceso y el tamaño de la población objetivo. Los resultados reflejaron la ausencia de alteraciones respiratorias y se identificaron cuidados preventivos importantes como la vacunación y deficiencias que alertan sobre la necesidad de intervenciones educativas para los cuidadores.
Development of a Clinical Prediction Model for Diabetes in Chronic Pancreatitis: The PREDICT3c Study
Authors: Jeon Christie , Hart Phil A. , Li Liang , Yang Yunlong , Chang Eleanor , Bellin Melena D. , Fisher William E. , Fogel Evan L. , Forsmark Christopher E. , Park Walter G. , K. Van Den Eeden Stephen , Vege Santhi Swaroop , Serrano José , Whitcomb David C. , Andersen Dana K. , Conwell Darwin L. , Yadav Dhiraj , Goodarzi Mark O 
Published: November 2022

<p> </p>
<p><strong>Objective</strong>: Diabetes arising in chronic pancreatitis (CP) is associated with increased morbidity and mortality. Thus, methods to predict which CP patients are at greatest risk for diabetes are urgently needed. We aimed to examine independent risk factors for diabetes in a large cohort of CP. </p>
<p><strong>Research Design and Methods</strong>: This cross-sectional study consisted of 645 individuals enrolled in the PROCEED study with CP, of whom 276 had diabetes. We conducted univariable and multivariable regression analyses of potential risk factors for diabetes. Model performance was assessed with area under the receiver operating curve (AUROC) analysis, and accuracy was evaluated by cross-validation. Exploratory analyses stratified the diabetes cases according to the timing of development of diabetes relative to the diagnosis of pancreatitis. </p>
<p><strong>Results</strong>: Independent correlates of diabetes in CP included risk factors for type 2 diabetes (older age, overweight/obese status, male, non-White race, tobacco use) as well as pancreatic disease-related factors (history of acute pancreatitis complications, non-alcoholic etiology of CP, exocrine pancreatic dysfunction, pancreatic calcification, pancreatic atrophy) (AUROC 0.745). Type 2 diabetes risk factors predominated in diabetes occurring before pancreatitis, and pancreatic disease-related factors predominated in diabetes occurring after pancreatitis. </p>
<p><strong>Conclusion</strong>: Multiple factors are associated with diabetes in CP, including canonical risk factors for type 2 diabetes and features associated with pancreatitis severity. This study lays the groundwork for the future development of models integrating clinical and non-clinical data to identify CP patients at risk for diabetes and identifies modifiable risk factors (obesity, smoking) on which to focus for diabetes prevention. </p>
To question of manufacturing zinc reference electrodes for sea-going vessels and ships
Authors: Yastrebov Dmitry Pavlovich 
Published: November 2022

The article highlights the urgent problem of corrosion protection monitoring of sea-going vessels and ships. Nowadays, the ship teams provide the control by measuring the potential of the ship hull using reference electrodes. There are given the results of monitoring the corrosion protection of the hull of the sea-going vessel PM-15 project No. 304/III. The control system is based on the results of measuring the potential of the ship hull. The measurements were taken using a standard silver chloride reference electrode (SCE) and two nonstandard electrodes made of galvanized steel. In manufacturing the non-standard reference electrodes there were taken into account the requests of the crews of sea-going vessels of the Kamchatka fleet. Testing the reference electrodes of galvanized steel proves that the results of measuring the potential of the ship hull can be classified as accurate measurements in accordance with GOST R 8.736-2011. The measuring results are quite stable according to GOST R 8.736-2011. It has been stated that the cost of CSE is several times higher than the cost of reference electrodes made of galvanized steel. The process of storing and transporting CSE is more labour-intensive compared to the galvanized steel reference electrodes. The galvanized steel reference electrodes provided for protecting the marine hulls from corrosion are recommended for use. It has been inferred that manufacture and application of non-standard reference electrodes on ships can be provided by ship repair crews. The study results can be used by the crews of sea-going vessels to control the protection
of ship hulls against corrosion.
PENDAMPINGAN PRAKTIKUM IPA BIOLOGI PESERTA DIDIK MAN 2 BARRU
Authors: Ali Ahmad , Rapi Muh , Arif Wiwin Pramita , Rivai Andi Tenri Ola , Zulkarnaim Zulkarnaim , Ibrahim Ayyub 
Published: November 2022

Kegiatan praktikum merupakan kegiatan wajib pada pembelajaran sains khususnya biologi. Praktikum menjadikan pengalaman peserta didik untuk menunjukkan keterampilan proses dalam menemukan teori atau fakta maupun sebatas pembuktian teori yang telah ada. Sayangnya Kegiatan praktikum belum dilaksanakan secara optimal di MAN 2 Barru mengingat keterbatasan alat dan bahan yang ada. Pengabdian ini dilaksanakan di Madrasah Aliyah Negeri 2 Barru dengan subjek pendampingan adalah peserta didik kelas X, XI, XII yang berjumlah 20 orang. Praktikum yang dilaksanakan berjumalah 6 topik dengan menggunakan bahan dan alat sederhana yang dapat dijumpai di sekitar sekolah atau lingkungan sekitar. Praktikum menunjukkan antusias peserta didik dalam mengikuti praktikum. Peserta didik telah mampu menggunakan mikroskop, membuat preparate, dan mengamati di bawah mikroskop, membedah katak dan menunjukkan bagian morfologi dan anatominya, membuat hipotesis dan menarik kesimpulan pada setiap topik praktikum.
Green tea improves rat sperm quality and reduced cadmium chloride damage effect in spermatogenesis cycle
Authors: Mahmoudi Reza ,   Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran, Azizi Arsalan ,   Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran, Abedini Soheila ,   Biology Department, Azad University of Jahrom, Jahrom, Iran, Hemayatkhah Jahromi Vahid ,   Biology Department, Azad University of Jahrom, Jahrom, Iran, Abidi Hassan ,   Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran, Jafari Barmak Mehrzad ,   Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran,   Mehrzad Jafari Barmak, Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran; Tel.: +98–743 3230290; E-mail: mehrzadj14@gmail.com.
Published: November 2022

Introduction
Testicular tissue is part of the reproductive system that some mineral compounds such as cadmium chloride (CdCl2) destroy. Green tea (Camellia sinensis) extract can reduce the tissue damage caused by toxins due to its antioxidant properties. The aim of this study was to evaluate the effect of green tea extract on sperm quality in cadmium chloride toxicity.

Materials and Methods
In the present study, male Wistar rats were allotted randomly into four groups, namely control group (C), CdCl2 (1.5mg/kg), GT 1.5% (w/v) and in combinationCdCl2+GT groups. CdCl2 was injected intraperitoneally (1.5 mg /kg) whereas the green tea extract was administrated orally. At 13, 25 and 49 days after treatment, the rats were euthanized and the reproductive organs (testes, epididymis) were excised and used for sperm analysis and histo-morphometric examinations.

Results
The mean of the diameter of seminiferous tubes, the number of spermatogonia, Sertoli, Leydig cells and thickness of the germinal layer in the testis were significantly increased (P<0.05) in all groups compared to the CdCl2 group (P<0.05). Sperm motility, sperm count and testosterone were significantly decreased in the CdCl2 group compared to all groups of treatment (p<0.05). The mean of MDA was significantly increased in the CdCl2 group compared to other groups (p<0.05).

Conclusion
Green tea has an antioxidant effect that reduces the effects of free oxygen radicals produced from toxins such as cadmium chloride. In addition, it could decrease lipid peroxidation of the cell membrane and ultimately prevent the destruction of tissues in the long run.
Cost-Effectiveness Analysis of Treatment for Metastatic Renal Carcinoma in Romania
Authors: Liviu Preda Alin ,   Public Health and Management Department, Carol Davila University of Medicine and Pharmacy, Bucharest,   Alin Liviu Preda, Catedra de Sanatate Publica si Management, Institutul de Sanatate Publica, Str. Dr. Leonte Anastasievici Nr.1-3, Sector 5, cod: 050463, Bucharest, Romania, Galieta Mincă Dana ,   Public Health and Management Department, Carol Davila University of Medicine and Pharmacy, Bucharest
Published: November 2022

RationaleIn recent years, the cost of several treatment options for renal cancer have been supported by the Romanian healthcare system for both first- and second-line therapies. First-line alternatives through real-life efficacy and amplitude of adverse reactions may influence the efficacy and costs of patients treated with second-line treatment.ObjectiveEstimation of the cost-effectiveness and cost-benefit ratio for first-line treatment alternatives: Sunitinib and Pazopanib from the payer’s perspective in the Romanian healthcare system.Methods and ResultsWe developed a Markov model to calculate the cost-effectiveness and cost-benefit ratio for 2 cohorts of patients using the results from the COMPARZ study for efficacy (progression-free survival, general survivability and quality of life) and safety and costs from national hospital databases. For an estimated population of 800 patients, Pazopanib has a quantified benefit of 7.19 years in progression-free survival, 11.71 life years gained and 8.97 years of quality-adjusted life-years compared to Sunitinib. The analysis is limited by the accuracy of the national data used and the transposition of general data on efficacy and safety at the local level.
The Attitude of Patients from a Romanian Tertiary Cardiology Center as Regards Participation in Biomarker-Based Clinical Trials – Survey Methodology
Authors: Mihaela Micheu Miruna ,   Department of Cardiology, Clinical Emergency Hospital of Bucharest, Bucharest, Romania,   Miruna Mihaela Micheu, Department of Cardiology, Clinical Emergency Hospital of Bucharest, Floreasca street 8, 014461, Bucharest, Romania, Phone: +40722451755, E-mail: mirunamicheu@yahoo.com., Udrea Oana-Maria ,   Department of Psychology, “Grigore Alexandrescu” Clinical Hospital of Bucharest, Bucharest, Romania, Octavia Popa Mihaela ,   University of Medicine and Pharmacy Carol Davila, Bucharest, Romania, Rusu Iulia ,   University of Medicine and Pharmacy Carol Davila, Bucharest, Romania, Gheorghe-Fronea Oana ,   Department of Cardiology, Clinical Emergency Hospital of Bucharest, Bucharest, Romania,   University of Medicine and Pharmacy Carol Davila, Bucharest, Romania, Scafa-Udriste Alexandru ,   Department of Cardiology, Clinical Emergency Hospital of Bucharest, Bucharest, Romania,   University of Medicine and Pharmacy Carol Davila, Bucharest, Romania, Dorobantu Maria ,   Department of Cardiology, Clinical Emergency Hospital of Bucharest, Bucharest, Romania,   University of Medicine and Pharmacy Carol Davila, Bucharest, Romania
Published: November 2022

One of the challenges faced when conducting a clinical trial is the recruitment of the proposed number of participants. Accordingly, identifying barriers to patients’ enrollment and developing effective strategies to overcome them is mandatory. One of the main strategies employed to improve participation rate consists of designing the informed consent forms based on patients’ feedback. This survey aims to explore the attitude of patients admitted in a Romanian tertiary cardiology center to take part in biomarker-based clinical trials.
This is a descriptive, prospective and longitudinal single-center study. Participants will be recruited until the planned sample size will be reached (n=333). The patients will be interviewed based on a semi-structured questionnaire which includes four sections: demographics (7 items), personal medical history (7 items), attitudes (9 items) and trust (4 items). Descriptive statistics will be used to illustrate patients’ demographics, medical history, attitudes toward biomarker-based clinical trials and trust in medical researchers. Logistic regression models will be employed to assess relations between patients’ attitudes, trust, and different socio-demographic variables.
Data analysis will offer answers to key questions addressed by this survey: What amount of and in what form should information be disclosed? Who should make the invitation to participate?
The information gained will facilitate tailoring informed consent forms to suit the needs of patients with various demographic, social and educational backgrounds.
حشر الأجساد بين الفلاسفة والمتكلمين دراسة مقارنة
Authors: Thamer Atshan Yassin 
Published: November 2022

يعد هذا البحث صورة من صور المناقشة لمسألة عقائدية مهمة وحساسة من مسائل العقائد المتعلقة بالسمع بين مدرستين من المدارس الكبيرة التي ينتسب اليها كثير من أرباب العقول من العلماء والنظار, وهم مدرسة الاشاعرة من المتكلمين و مدرسة الفلاسفة الاسلاميين, حيث ناقش البحث مقصد الفلاسفة في تحديد معنى الحشر وتقييدهم اياه بالحشر الروحاني وانكارهم للحشر الجسماني, وبين الأشاعرة الذين أثبتوا الحشر بصورتيه ومناقشة أدلة الطرفين, وبيان مواطن الضعف والقوة لدى الفريقين. كما بين البحث المعاني المرادفة والمرتبطة بهذه المسالة وتحديد ادلتها ومصادرها.
Aplikasi Zat Pengatur Tumbuh Asam Giberelat (Ga3) dan Pengaruhnya terhadap Pertumbuhan dan Produksi Bawang Merah (Allium ascalonicum L.) di Desa Datar Kecamatan Sumbang pada Musim Hujan
Authors: Jati Ignatius Drajat Krisna , Rostaman Rostaman , Rokhminarsi Eny 
Published: November 2022

The purpose of this research was to determine the effect and the best concentration of GA3 growth regulator on the growth and yield of shallots. The research was carried out in the rice fields of Datar Village, Sumbang District, Banyumas Regency, from February to April 2022. This study was a non-factorial field experiment using a randomized block design with 5 treatments and 5 replications. The treatment was the concentration of GA3 with 5 levells, namely 0 ppm, 250 ppm, 500 ppm, 750 ppm and 1000 ppm. The conclusion of this study is the application of GA3growth regulator affected increasing the number of tillers leaf area, bulb number/clump, fresh bulb weight/clump, dry bulb with dry leaves weight/clump, absolute dry bulb weight/clump, yield/plots and yield/hectare. Application of 500 ppm GA3growth regulator showed the best growth and yield of shallot. It was indicated by the number of tillers, leaf area and yield/hectare of 11.54 plants, 1162.18 cm2 and 16.54 ton, respectively
Inovasi Pertanian Ramah Lingkungan Terhadap Produktivitas Padi Sawah
Authors: Supriyo Agus 
Published: November 2022

Peningkatan produktivitas tanaman pangan khususnya padi yang diikuti aspek kelestarian lingkungan merupakan prinsip penerapan pertanian ramah lingkungan. Pertanian organik merupakan salah satu sistem usahatani yang ramah lingkungan, produk pangan organik mempunyai pangsa pasar yang khusus. Berbagai sistem penerapan pertanian ramah lingkungan berpedoman pada sistem budidaya pertanian yang benar melalui sinergi antar komponen teknologi antara lain pengelolaan tanaman terpadu (PTT), Jajar legowo super dan pengendalian organisme pengganggu tanaman (OPT) secara terpadu. Penerapan PTT Ramah lingkungan yang terdiri atas komponen teknologi terpilih dapat meningkatkan produktivitas tanaman pangan (padi) dan menurunkan emisi gas rumah kaca (GRK). Beberapa komponen teknologi yang dapat meningkatkan produktivitas tanaman padi dan menurunkan emisi GRK meliputi penggunaan inokulan sebagai perlakuan benih, cara tanam jajar legowo, irigasi berselang (intermittent irigation), penggunaan bahan organik (C/N rendah), dengan bantuan bio-dekomposer dan pemupukan berimbang, pengendalian hama terpadu dengan memanfaatkan pestisida nabati dan aplikasi pestisida setelah mencapai ambang kendali. Penerapan PTTPetro padi sawah ramah lingkungan dapat memberikan hasil tertinggi (5.390 t gkg/ha) atau meningkatkan hasil padi sebesar 30 persen diatas kontrol (hasil 3.620 t gkg/ha) dan menurunkan emisi gas methan (CH4) sebesar 13,6% dibawah kontrol (emisi gas methan sebesar: 76,05 kg CH4/ha/musim) menjadi 65.69 kg CH4/ha/musim.