bluuebunny/crossref_metadata_2025_split huggingface dataset:
IMPLEMENTATION OF MOORA METHOD FOR DECISION SUPPORT SYSTEM SCHOLARSHIP SELECTION IN SMK MUHAMMADIYAH PRAMBANAN
Authors: Perdana Dinar Abdi , Prabowo Donni , Sari Bety Wulan 
Published: June 2022

Decision Support System for Scholarship Selection at SMK Muhammadiyah Prambanan Using the MOORA Method aims to implement the Multi-Objective Optimization method on the basis of Ration Analysis. In determining scholarship recipients based on predetermined criteria and building a system in the form of a website to help provide alternative decisions in determining the acceptance of scholarships at SMK Muhammadiyah Prambanan. Based on the source of the data obtained, using primary data including interview and observation methods supported by secondary data obtained by literature studies that are relevant to the problem. Scholarship data is calculated and then ranked based on the final value generated from the MOORA calculation. The process of scholarships selection is based on criteria including report card grades, dependents of parents, the income of parents, percentage of attendance, and the number of siblings. The results of this study are the Scholarship Selection Decision Support System Using the MOORA Method, where the final value in the form of an alternative that has the greatest preference value will be placed at the top rank. The alternative will be a recommendation to receive a scholarship.
¿La raza, un constructo social o biológico? Nueva ecuación para estimar la tasa de filtración glomerular sin considerar a la raza
Authors: Azañero-Haro Johan 
Published: June 2022

La tasa de filtración glomerular (TFG) es un índice que mide la velocidad a la que se filtra la sangre por minuto en los corpúsculos renales de ambos riñones, y que suele ser alrededor e 125 mL/min en los hombres y 105 mL/min en las mujeres. La medición de la TFG se hace mediante la prueba de Depuración de Creatinina con recolección de orina de 24 o 2 horas y no es viable en su inmediatez para su valoración en la práctica diaria, por ello se han desarrollado diversas ecuaciones matemáticas que permitan su estimación(1). Durante los últimos años, la TFG ha sido considerada como el mejor índice para evaluar la función renal, siendo muy importante en la atención médica de todo paciente.
PERENCANAAN PARTISIPATIF DALAM PENYUSUNAN RENCANA DETAIL TATA RUANG KOTA WAISAI, RAJA AMPAT, PAPUA
Authors: Yuniartanti Rizki Kirana 
Published: June 2022

Salah satu agenda Prioritas Pembangunan Nasional Pemerintah dalam Rencana Pembangunan Jangka Menengah Nasional (RPJMN) 2020-2024 adalah mengembangkan wilayah untuk mengurangi kesenjangan dan menjamin pemerataan. Upaya ini dilakukan melalui penyusunan Rencana Detail Tata Ruang (RDTR). RDTR sebagai acuan untuk pengajuan konfirmasi/persetujuan Kesesuaian Kegiatan Pemanfaatan Ruang (KKPR) yang dapat dilakukan sesuai tingkat risikonya sesuai standar maupun kualitas ruang atau lingkungan. Kawasan Perkotaan Waisai, Kabupaten Raja Ampat Provinsi Papua Barat sebagai salah satu wilayah yang sangat memerlukan percepatan penyusunan RDTR dikarenakan peluang investasi yang besar disana, khususnya sektor pariwisata.
Penyusunan RDTR Kawasan Perkotaan Waisai dengan menerapkan konsep perencanaan partisipatif. Hal ini dikarenakan masyarakat sebagai penerima manfaat dari penyusunan RDTR Kawasan Perkotaan Waisai. Dalam penelitian ini akan menjabarkan proses penyusunan RDTR Kawasan Perkotaan Waisai yang menerapkan konsep perencanaan partisipatif. Kemudian dalam penelitian ini juga akan menilai tingkat partisipasi masyarakat dalam setiap kegiatan forum diskusi dan konsultasi publik yang dilaksanakan dengan pendekatan penelitian kombinasi (mixed method research) dan alat analisis skoring. Dari penelitian ini akan menilai tingkat pelibatan masyarakat dalam penyusunan RDTR, sekaligus kontribusi nyata dari pelibatan masyarakat tersebut. Dengan adanya penelitian ini diharapkan dapat menjadi contoh pembelajaran penyusunan RDTR di Kabupaten Raja Ampat pada khususnya dan wilayah lain di Indonesia pada umumnya dengan menerapkan konsep partisipasi masyarakat.
Bladder Acellular Matrix Prepared by a Self-Designed Perfusion System and Adipose-Derived Stem Cells to Promote Bladder Tissue Regeneration
Authors: Xiao Shuwei , Wang Pengchao , Zhao Jian , Ling Zhengyun , An Ziyan , Fu Zhouyang , Fu Weijun , Zhou Jin , Zhang Xu 
Published: June 2022

The bladder patch constructed with the bladder acellular matrix (BAM) and adipose-derived stem cells (ASCs) was incubated with the omentum for bladder reconstruction in a rat model of bladder augmentation cystoplasty. A self-designed perfusion system and five different decellularization protocols were used to prepare the BAM. Finally, an optimal protocol (group C) was screened out by comparing the cell nucleus residue, collagen structure preservation and biologically active components retention of the prepared BAM. ASCs-seeded (BAM-ASCs group) and unseeded BAM (BAM group) were incubated with the omentum for 7 days to promote neovascularization and then perform bladder reconstruction. Hematoxylin and eosin and Masson’s trichrome staining indicated that the bladder patches in the BAM-ASCs group could better regenerate the bladder wall structure compared to the BAM group. Moreover, immunofluorescence analyses demonstrated that the ASCs could promote the regeneration of smooth muscle, neurons and blood vessels, and the physiological function (maximal bladder capacity, max pressure prior to voiding and bladder compliance) restoration in the BAM-ASCs group. The results demonstrated that the self-designed perfusion system could quickly and efficiently prepare the whole bladder scaffold and confirmed that the prepared BAM could be used as the scaffold material for functional bladder tissue engineering applications.
In vitro Exposure to Inflammatory Mediators Affects the Differentiation of Mesenchymal Progenitors
Authors: Marsh S. , Constantin-Teodosiu T. , Chapman V. , Sottile V. 
Published: June 2022

The increasing prevalence of joint disease, and in particular osteoarthritis (OA), calls for novel treatment strategies to prevent disease progression in addition to existing approaches focusing mainly on the relief of pain symptoms. The inherent properties of mesenchymal stem cells (MSCs) make them an attractive candidate for novel tissue repair strategies, as these progenitors have the potential to differentiate into chondrocytes needed to replace degraded cartilage and can exert a modulating effect on the inflammatory environment of the diseased joint. However, the inflammatory environment of the joint may affect the ability of these cells to functionally integrate into the host tissue and exert beneficial effects, as hinted by a lack of success seen in clinical trials. Identification of factors and cell signalling pathways that influence MSC function is therefore critical for ensuring their success in the clinic, and here the effects of inflammatory mediators on bone marrow-derived MSCs were evaluated. Human MSCs were cultured in the presence of inflammatory mediators typically associated with OA pathology (IL-1β, IL-8, IL-10). While exposure to these factors did not produce marked effects on MSC proliferation, changes were observed when the mediators were added under differentiating conditions. Results collected over 21 days showed that exposure to IL-1β significantly affected the differentiation response of these cells exposed to chondrogenic and osteogenic conditions, with gene expression analysis indicating changes in MAPK, Wnt and TLR signalling pathways, alongside an increased expression of pro-inflammatory cytokines and cartilage degrading enzymes. These results highlight the value of MSCs as a preclinical model to study OA and provide a basis to define the impact of factors driving OA pathology on the therapeutic potential of MSCs for novel OA treatments.
Modifying SnS2 With Carbon Quantum Dots to Improve Photocatalytic Performance for Cr(VI) Reduction
Authors: Li Weidong , Qiu Jianping , Jin Haihong , Wang Yuanyuan , Ma Dandan , Zhang Xinxiang , Yang Huayun , Wang Fangyuan 
Published: June 2022

The photoreduction for hazardous Cr(VI) in industrial wastewater has been considered a “green” approach with low-cost and easy-to-go operation. SnS2 is a promising narrow bandgap photocatalyst, but its low charge carrier separation efficiency should be solved first. In this work, N-doped carbon quantum dots (CQDs) were prepared and loaded onto SnS2 nanoparticles via an in situ method. The resulting composite samples (NC@SnS2) were characterized, and their photocatalytic performance was discussed. SnS2 nanoparticles were obtained as hexagonal ones with a bandgap of 2.19 eV. The optimal doping level for NC@SnS2 was citric acid: urea:SnS2 = 1.2 mmol:1.8 mmol:3.0 mmol. It showed an average diameter of 40 nm and improved photocatalytic performance, compared to pure SnS2, following a pseudo-first-order reaction with a kinetic rate constant of 0.1144 min−1. Over 97% of Cr(VI) was photo-reduced after 30 min. It was confirmed that modification of SnS2 with CQDs can not only improve the light-harvesting ability but also stimulate the charge separation, which therefore can enhance the photoreactivity of SnS2 toward Cr(VI) reduction. The excellent stability of NC@SnS2 indicates that it is promising to be practically used in industrial wastewater purification.
The Punta de la Mona Rhodolith Bed: Shallow-Water Mediterranean Rhodoliths (Almuñecar, Granada, Southern Spain)
Authors: Del Río Jesús , Ramos Dino Angelo , Sánchez-Tocino Luis , Peñas Julio , Braga Juan Carlos 
Published: June 2022

Shallow-water rhodolith beds are rare in the Mediterranean Sea and generally poorly known. The Punta de la Mona rhodolith bed extends for 16,000 square meters in shallow and oligotrophic waters at the southern coast of Spain, off Almuñecar in the Alborán Sea. We present a detailed analysis of the structure (rhodolith cover and density, rhodolith size and shape, sediment granulometry) and morphospecies composition of the bed along a depth gradient. A stratified sampling was carried out at six depths (9, 12, 15, 18, 21, and 24 m), estimating rhodolith cover and abundance; rhodoliths were collected from one 30 by 30 cm quadrat for each transect, resulting in 18 samples and a total of 656 rhodoliths. The collected rhodoliths were measured and the coralline algal components identified morphoanatomically through a stereomicroscope and SEM. Sediment on the seafloor mainly consisted of pebbles and cobbles; the highest rhodolith cover occurred between 15 and 18 m, and the lowest at the shallowest and deepest transects (9 and 24 m). Mean Rhodolith size was similar throughout the depth range (23–35 mm) with a slight increase at 24 m, although the largest rhodoliths occurred at 21 m. In monospecific rhodoliths, size depended more on the forming species than on depth. We found 25 non-geniculate coralline morphospecies, nearly all rhodolith-forming morphospecies reported in the Mediterranean Sea in recent accounts. The highest morphospecies richness (18–19) and proportional abundance were found at intermediate depths (15–18 m), where rhodolith cover is also highest. Lithophyllum incrustans and Lithophyllum dentatum dominated at shallow depths (9–12 m), whereas Lithothamnion valens was the dominant species at intermediate and greater depths. Overall, the latter species was the most common in the rhodolith bed. The shallow-water rhodolith bed in Punta de la Mona is probably the most diverse in the Mediterranean Sea. This highlights the importance of the conservation of this habitat and, in general, emphasizes the role of the Alborán Sea as a diversity center of coralline algae. The Punta de la Mona example contradicts the common assumption in the geological literature that rhodolith beds are indicative of oligophotic environments with high nutrients levels.
Chronology and Eruption Dynamics of the Historic∼1700 CE Eruption of Tseax Volcano, British Columbia, Canada
Authors: Le Moigne Yannick , Williams-Jones Glyn , Vigouroux Nathalie , Russell James K. 
Published: June 2022

Despite having relatively short timespans of eruptions, monogenetic volcanoes can pose significant risks to the nearby population. Here, we describe the ∼1700 CE eruption of Tseax volcano, British Columbia, which killed up to 2,000 people of the Nisga’a First Nation and is ranked as Canada’s worst natural disaster. Within the Nisga’a culture, Adaawak stories preserve an observational account of the Tseax eruption. In this study, we establish the chronology of the eruption by integrating field observations and petrophysical data informed by Nisga’a oral and written histories. The Nisga’a stories corroborate the short duration and exceptional intensity of the eruption as recorded in the volcanic products. The eruption was divided in two main periods: 1) Period A and 2) Period B. 1) The eruption started in a typical Hawaiian style with low levels of lava fountaining that built up a spatter rampart. This pyroclastic edifice was breached by voluminous pāhoehoe lavas erupted at high discharge rates. We estimate that almost half of the emplaced lava volume (0.20 km3) was erupted in Period A and had a flux of 800–1,000 m3/s. The low viscosity lava reached the Nass Valley, 20 km downstream of the volcano, in “swift currents”, and engulfed the former Nisga’a villages in only 1–3 days, thus likely being responsible for the reported fatalities. The discharge rates progressively diminished to 10–200 m3/s until the end of this first eruptive period, which lasted a few weeks to a few hundred days. 2) The Period B eruption produced two ‘a‘ā lavas with discharge rates &lt;50 m3/s. This period was also characterised by an explosive phase of eruption that built a 70 m high tephra cone overlapping with a spatter rampart; Period B lasted approximately 20 days. In total, the eruption produced 0.5 km3 of volcanic materials (mostly in the form of lava flows) on the order of weeks to a few months. The mountainous terrain significantly controlled the emplacement of lava flows that reached long distances in a short amount of time. Our work shows that, under certain conditions, eruptions of small-volume monogenetic volcanoes ca pose risks comparable to flank eruptions on long-lived shield volcanoes.
Prediction of River Pollution Under the Rainfall-Runoff Impact by Artificial Neural Network: A Case Study of Shiyan River, Shenzhen, China
Authors: Tian Zhan , Yu Ziwei , Li Yifan , Ke Qian , Liu Junguo , Luo Hongyan , Tang Yingdong 
Published: June 2022

Climate change and rapid urbanization have made it difficult to predict the risk of pollution in cities under different types of rainfall. In this study, a data-driven approach to quantify the effects of rainfall characteristics on river pollution was proposed and applied in a case study of Shiyan River, Shenzhen, China. The results indicate that the most important factor affecting river pollution is the dry period followed by average rainfall intensity, maximum rainfall in 10 min, total amount of rainfall, and initial runoff intensity. In addition, an artificial neural network model was developed to predict the event mean concentration (EMC) of COD in the river based on the correlations between rainfall characteristics and EMC. Compared to under light rain (&lt; 10 mm/day), the predicted EMC was five times lower under heavy rain (25–49.9 mm/day) and two times lower under moderate rain (10–24.9 mm/day). By converting the EMC to chemical oxygen demand in the river, the pollution load under non-point-source runoff was estimated to be 497.6 t/year (with an accuracy of 95.98%) in Shiyan River under typical rainfall characteristics. The results of this study can be used to guide urban rainwater utilization and engineering design in Shenzhen. The findings also provide insights for predicting the risk of rainfall-runoff pollution and developing related policies in other cities.
The First Fossil of Nossidiinae From Mid-Cretaceous Amber of Northern Myanmar (Coleoptera: Ptiliidae)
Authors: Li Yan-Da , Newton Alfred F. , Huang Di-Ying , Cai Chen-Yang 
Published: June 2022

Ptiliidae is a group of distinctly miniaturized staphylinoid beetles with a scarce fossil record. Here, we report a new ptiliid genus and species,Crenossidium slipinskiiLi, Newton and Caigen. et sp. nov., from mid-Cretaceous amber from northern Myanmar.Crenossidiumcan be attributed to the subfamily Nossidiinae based on the hind wing morphology, which has also been confirmed through phylogenetic analyses.Crenossidiumdiffers from other extant nossidiine genera in the combination of the wide apical maxillary palpomeres, posteriorly widest pronotal disk, (almost) contiguous procoxae, fewer setae along wing margin, and multidentate pygidium.urn:lsid:zoobank.org:pub:8038D763-6856-4AC5-972C-E20D636137EE.
Identification of Key Endometrial MicroRNAs and Their Target Genes Associated With Pathogenesis of Recurrent Implantation Failure by Integrated Bioinformatics Analysis
Authors: Shang Jin , Cheng Yan-Fei , Li Min , Wang Hui , Zhang Jin-Ning , Guo Xin-Meng , Cao Dan-dan , Yao Yuan-Qing 
Published: June 2022

Purpose: Recurrent implantation failure (RIF) is an enormous challenge for in vitro fertilization (IVF) clinicians. An understanding of the molecular mechanisms of RIF helps to predict prognosis and develop new therapeutic strategies. The study is designed to identify diagnostic biomarkers for RIF as well as the potential mechanisms underlying RIF by utilizing public databases together with experimental validation.Methods: Two microarray datasets of RIF patients and the healthy control endometrium were downloaded from the Gene Expression Omnibus (GEO) database. First, differentially expressed microRNAs (miRNAs) (DEMs) were identified and their target genes were predicted. Then, we identified differentially expressed genes (DEGs) and selected hub genes through protein-protein interaction (PPI) analyses. Functional enrichment analyses of DEGs and DEMs were conducted. Furthermore, the key DEMs which targeted these hub genes were selected to obtain the key miRNA–target gene network. The key genes in the miRNA-target gene network were validated by a single-cell RNA-sequencing dataset of endometrium from GEO. Finally, we selected two miRNA–target gene pairs for further experimental validation using dual-luciferase assay and quantitative polymerase chain reaction (qPCR).Results: We identified 49 DEMs between RIF patients and the fertile group and found 136,678 target genes. Then, 325 DEGs were totally used to construct the PPI network, and 33 hub genes were selected. Also, 25 DEMs targeted 16 key DEGs were obtained to establish a key miRNA–target gene network, and 16 key DEGs were validated by a single-cell RNA-sequencing dataset. Finally, the target relationship of hsa-miR-199a-5p-PDPN and hsa-miR-4306-PAX2 was verified by dual-luciferase assay, and there were significant differences in the expression of those genes between the RIF and fertile group by PCR (p &lt; 0.05).Conclusion: We constructed miRNA–target gene regulatory networks associated with RIF which provide new insights regarding the underlying pathogenesis of RIF; hsa-miR-199a-5p-PDPN and hsa-miR-4306-PAX2 could be further explored as potential biomarkers for RIF, and their detection in the endometrium could be applied in clinics to estimate the probability of successful embryo transfer.
Does Infertility Stress Impair Sexual Function in Infertile Women and Men? A Cross-Sectional Study in Iran
Authors: Amraei Samira , Abedi Parvin , Nikbakht Roshan , Tadayon Mitra , Maraghi Elham 
Published: June 2022

BackgroundThe issue of infertility is a worldwide challenge, estimated to affect around 50 million couples. This study aimed to evaluate the relationship between infertility stress and sexual function in men and women with infertility.MethodsIn this cross-sectional study, 300 men and women with infertility were recruited. A demographic questionnaire, the Fertility Problem Inventory, the Female Sexual Function Scale (FSFI), and the International Index of Erectile Function (IIEF) were used to collect data. Independent t-test, Chi-square, and linear and logistic regressions were used to assess the data.ResultsThe total score of sexual function in women and men was 22.18 ± 7.86 and 57.7 ± 17.8, respectively. Infertility duration and the ability to pay for the costs of infertility treatment had a significant relationship with sexual function in women. A significant association was found between communication concerns and sexual function scores in men with infertility. Infertile women had more sexual concerns, while infertile men had more communication concerns.ConclusionThis study showed that women with infertility had more infertility stress than men with infertility. Women with higher infertility duration and the inability to pay for the infertility treatment costs impaired sexual function. Women with infertility had more sexual concerns, while Men with infertility had more communication concerns. Policymakers need to consider strategies such as counseling for men and women with infertility to help them cope with their problems, especially their psychological problems. The lack of random enrollment of participants and lack of control group were the limitations of this study.
Frontal, Sensorimotor, and Posterior Parietal Regions Are Involved in Dual-Task Walking After Stroke
Authors: Lim Shannon B. , Peters Sue , Yang Chieh-ling , Boyd Lara A. , Liu-Ambrose Teresa , Eng Janice J. 
Published: June 2022

BackgroundWalking within the community requires the ability to walk while simultaneously completing other tasks. After a stroke, completing an additional task while walking is significantly impaired, and it is unclear how the functional activity of the brain may impact this.MethodsTwenty individual in the chronic stage post-stroke participated in this study. Functional near-infrared spectroscopy (fNIRS) was used to measure prefrontal, pre-motor, sensorimotor, and posterior parietal cortices during walking and walking while completing secondary verbal tasks of varying difficulty. Changes in brain activity during these tasks were measured and relationships were accessed between brain activation changes and cognitive or motor abilities.ResultsSignificantly larger activations were found for prefrontal, pre-motor, and posterior parietal cortices during dual-task walking. Increasing dual-task walking challenge did not result in an increase in brain activation in these regions. Higher general cognition related to lower increases in activation during the easier dual-task. With the harder dual-task, a trend was also found for higher activation and less motor impairment.ConclusionsThis is the first study to show that executive function, motor preparation/planning, and sensorimotor integration areas are all important for dual-task walking post-stroke. A lack of further brain activation increase with increasing challenge suggests a point at which a trade-off between brain activation and performance occurs. Further research is needed to determine if training would result in further increases in brain activity or improved performance.