bluuebunny/crossref_metadata_2025_split huggingface dataset:
Environmental Performance, Corporate Governance and Financial Performance of Chinese Heavy Polluted Industries
Authors: Anqi Chen , San Ong Tze 
Published: May 2022

Heavy polluted industries are the primary source of environmental pollution. In the case of the decline of ecological carrying capacity, how to ensure the necessary protection of the environment and the development of financial benefits, and whether corporate governance can regulate environmental performance and financial performance will be explored. This paper uses IBM SPSS Statistics 26.0 to conduct factor analysis to process dimensionality reduction on aggregate environmental performance based on statistics from heavy polluted industry companies listed on Shenzhen and Shanghai stock markets from 2015 to 2019. Then stata16.0 was used for regression analysis. It is found that a company’s aggregate environmental performance has a beneficial influence on its financial performance. Financial performance is also influenced by the size of the company and the rate at which revenues rise. Furthermore, the ratio of female board members has a beneficial effect on the link between a company’s aggregate environmental and financial performance, and the total number of committees has a strong negative impact on the relation between aggregate environmental and financial performance. These findings back up the agency, stakeholder, and resource-based theories, and they have significant consequences for the company’s management, legislators, and regulators.
Does Gender Diversity on Boards Influence Stock Market Liquidity? Empirical Evidence from the Tunisian Market
Authors: Abidi Ilyes , Nsaibi Mariem 
Published: May 2022

The aim of this paper is to study the effect of the gender diversity in boardrooms on the liquidity of the shares. To do this, we selected a sample made up of Tunisian banks listed over the period 1998-2018, and we used the two-step least squares method (2SLS). The results of this work show a significant and positive relationship between the gender diversity on the boards of directors and the liquidity of the shares of Tunisian banks. However, the results of this investigation suggest that the presence of at least one woman on the board positively affect the liquidity of the shares. This relationship becomes more meaningful when there is more than one woman on the board, but their presence will be normalized if they occupy at least three positions.
PENGARUH LITERASI KEUANGAN DAN LINGKUNGAN SOSIAL TERHADAP PERENCANAAN KEUANGAN PRIBADI
Authors: Fuadi Muhammad Noor , Trisnaningsih Sri 
Published: May 2022

Several survey results note that Indonesian people still carry out financial planning, in line with the diverse needs it is important to have the ability and skills to make finances. The purpose of this study was to examine and analyze the effect of financial literacy and social environment on personal financial planning for students of the UPN "Veteran" Jawa Timur Accounting Study Program. The sample used in this study found 94 respondents who were determined using the purposive sampling technique. Data analysis in this study was carried out using IBM SPSS 25 software. Based on testing and analysis, it was obtained that simultaneously (Test F) financial literacy variables and social environment variables affected the personal financial planning variable, partially (T-test) The individual financial literacy variable influences the personal financial planning variable, while the individual social environment variable does not affect the personal financial planning variable.
Keywords: Financial Planning, Literacy, Social Environment
DETERMINAN PERSEPSI MAHASISWA AKUNTANSI MENGENAI ETIKA ATAS PENGGELAPAN PAJAK (TAX EVASION)
Authors: Susanto Erika Aulia , Muslimin Muslimin 
Published: May 2022

Penggelapan pajak (tax evasion) merupakan tindakan pidana yang dijalankan oleh wajib pajak guna mengurangi jumlah pajak yang dibebankan atau tidak membayar pajak secara ilegal. Tujuan dari penelitian ini adalah guna melakukan penganalisisan terhadap sejumlah faktor yang memberikan imbas pengaruh terhadap pandangan mahasiswa akuntansi terkait etika terhadap penggelapan pajak (tax evasion). Penelitian ini menerapkan pendekatan kuantitatif. Populasi yang dipergunakan ialah mahasiswa Akuntansi Angkatan 2017 dan 2018 di Universitas Pembangunan Nasional “Veteran” Jawa Timur dan Universitas Airlangga. Teknik penentuan jumlah sampel menggunakan rumus Slovin sehingga menjadi 90 responden. Teknik analisis data menerapkan analisis regresi linier berganda yang diolah dengan bantuan SPSS. Hasil yang diperoleh pada penelitian ini memperlihatkan bahwa keadilan dan diskriminasi tidak berpengaruh terhadap persepsi mahasiswa akuntansi mengenai etika atas penggelapan pajak sedangkan sistem perpajakan berpengaruh terhadap persepsi mahasiswa akuntansi mengenai etika atas penggelapan pajak.
Kata Kunci: Keadilan, Sistem Perpajakan, Diskriminasi
COMPATIBILITY OF WASTE MANAGEMENT PLACES AT TPS3R KSM BAYU SUCI, SUB-DISTRICT MARGA
Authors: Devi Ni Putu Krusita Candra , Trimarianto Ciptadi 
Published: May 2022

<p>The pile of garbage is getting higher and land is starting to be limited at the Mandung TPA in Tabanan Regency to accommodate all the volume of incoming waste. The government's efforts to overcome the waste problem are by implementing independent waste management starting from the village through the TPS3R program. Currently, out of 133 villages in Tabanan Regency, only 11 villages have implemented and have TPS3R. One of the 11 TPS3R is the TPS3R KMS Bayu Suci in Batannyuh Village, Marga District. This study aims to determine the suitability of the capacity of the waste management site at TPS3R KSM Bayu Suci based on the standard of space requirements referring to the Technical Guidelines for the Implementation of Labor-Intensive Activities of the Directorate General of Human Settlements 2020. The importance of this research is to anticipate future problems that arise due to an increase in the volume of waste. but both in terms of processing equipment and land is not sufficient. The results of this study will show the extent and number of ideal equipment needed in maximizing the TPS3R program. The method used in this research is descriptive quantitative method by describing descriptively the data obtained in the field. The main data were obtained from the management of the Bayu Suci KSM and the Tabanan Regency Environmental Service. Based on the results of the study, that the minimum area of land required to maximize the service of TPS3R KSM Bayu Suci is 402 m2 with a minimum composting area of 201 m2. The composting system uses the drum method of 840 units. Based on current conditions, TPS3R KSM Bayu Suci has met the minimum land standard suitability by having a land area of 500m2, but it is still lacking in terms of hangar area for composting area which is only 75 m2 and the need to improve infrastructure to maximize waste processing services.<strong></strong></p><p> </p>
A contação de histórias como metodologia ativa: caminhos criativos e humanizados para a formação integral
Authors: Lima Antônio Carlos Santos de , Dos Santos Oliveira Gicele Rose 
Published: May 2022

O presente artigo tem como objetivo refletir sobre o lugar da contação de história no processo de formação integral. Concebida como metodologia ativa, essa prática, ao permitir os alunos a vivenciarem experiências que despertam as diversas dimensões humanas, contribuem para a construção do conhecimento num processo de aprendizagem significativa. Para essa reflexão, utilizamos a pesquisa exploratória, a qual compreende a primeira etapa de uma investigação mais ampla (Gil, 2008) e se centra na leitura de textos teóricos acerca do tema. A investigação mais ampla, nesse contexto, é uma pesquisa realizada em nível de mestrado profissional, cujo produto é um “Caderno de Oficinas” o qual sugere atividades com contação de histórias destinadas a alunos de Ensino Médio. Após a etapa de leituras do referencial teórico, correspondente à pesquisa exploratória, concluímos que a contação de histórias como metodologia ativa contribui para a formação integral dos alunos pelo seu caráter humanizado, proporcionando dinamicidade e criatividade no processo de ensino e aprendizagem.
Komparasi Metode Peramalan Harga Daging Ayam Broiler Di Kabupaten Banyuwangi Menggunakan Jaringan Syaraf Tiruan Backpropagation dan Model Multiplicative Holt-Winters
Authors: Hasanudin Slamet Ahmad Haris , Ischak Rabbani , Wulandari Sekar Ayu , Brillyantina Septine 
Published: May 2022

ABSTRAKHarga daging ayam broiler di Banyuwangi merepresentasikan data ekonomi yang memiliki fluktuasi musiman dengan variasi tidak konstan dan pola trend. Fluktuasi harga daging ayam broiler menjadi permasalahan dalam tingkat konsumsi daging ayam. Peramalan harga merupakan salah satu cara yang cara yang penting dalam menangani fluktuasi harga. Peneltian ini menggunakan metode jaringan syaraf tiruan backpropagation. Data yang digunakan pada penelitian ini adalah harga daging ayam broiler di Kabupaten Banyuwangi dalam kurun waktu 2014-2017. Hasil uji menggunakan metode jaringan syarat tiruan didapatkan nilai terbaik yaitu 12-10-1 (12 neuron input, 10 neuron hidden layer, 1 neuron output. Nilai n MAPE yang diperoleh sebesar 18,016 %. Selanjutnya, model Multiplicative Holt-Winters dengan tiga komponen parameter penghalusan, dimana komponen irregular-nya akan dihilangkan. Sehingga peramalan periode mendatang hanya dipengaruhi oleh konstanta level ( = 0,9989), komponen trend ( = 0,0056), dan musiman ( = 0,0008), pada periode ke-12 musiman sebelumnya. Akurasi peramalan menunjukkan bahwa model Multiplicative Holt-Winters dapat meminimalkan persentase kesalahan peramalan dengan Mean Absolute Percentage Error (MAPE) sebesar 12,63%, lebih baik dibandingkan Jaringan Syaraf Tiruan Backpropagation. Peramalan harga sangat penting dilakukan baik oleh industri peternakan maupun industri pengolah daging ayam. Peramalan harga yang tepat dapat dijadikan industri peternakan dan industri pengolah daging ayam untuk mengoptimalkan alokasi sumber daya sehingga dapat meningkatkan pendapatan. Kata Kunci: Backpropagation, Peramalan, Multiplicative Holt-Winters
“Orphan” Connexin43 in Plakophilin-2 Deficient Hearts Revealed by Volume Electron Microscopy
Authors: van Opbergen Chantal J. M. , Sall Joseph , Petzold Chris , Dancel-Manning Kristen , Delmar Mario , Liang Feng-Xia 
Published: May 2022

Previous studies revealed an abundance of functional Connexin43 (Cx43) hemichannels consequent to loss of plakophilin-2 (PKP2) expression in adult murine hearts. The increased Cx43-mediated membrane permeability is likely responsible for excess entry of calcium into the cells, leading to an arrhythmogenic/cardiomyopathic phenotype. The latter has translational implications to the molecular mechanisms of inheritable arrhythmogenic right ventricular cardiomyopathy (ARVC). Despite functional evidence, visualization of these “orphan” (i.e., non-paired in a gap junction configuration) Cx43 hemichannels remains lacking. Immuno-electron microscopy (IEM) remains an extremely powerful tool to localize, with nanometric resolution, a protein within its native structural landscape. Yet, challenges for IEM are to preserve the antigenicity of the molecular target and to provide access for antibodies to reach their target, while maintaining the cellular/tissue ultrastructure. Fixation is important for maintaining cell structure, but strong fixation and vigorous dehydration (as it is routine for EM) can alter protein structure, thus impairing antigen-antibody binding. Here, we implemented a method to combine pre-embedding immunolabeling (pre-embedding) with serial block-face scanning electron microscopy (SBF-SEM). We utilized a murine model of cardiomyocyte-specific, Tamoxifen (TAM) activated knockout of PKP2. Adult hearts were harvested 14 days post-TAM, at this time hearts present a phenotype of concealed ARVC (i.e., an arrhythmogenic phenotype but no overt structural disease). Thick (200 µm) vibratome slices were immunolabelled for Cx43 and treated with nanogold or FluoroNanogold, coupled with a silver enhancement. Left or right ventricular free walls were dissected and three-dimensional (3D) localization of Cx43 in cardiac muscle was performed using SBF-SEM. Reconstructed images allowed us to visualize the entire length of gap junction plaques, seen as two parallel, closely packed strings of Cx43-immunoreactive beads at the intercalated disc. In contrast, in PKP2-deficient hearts we observed bulging of the intercellular space, and entire areas where only one of the two strings could be observed, indicating the presence of orphan Cx43. We conclude that pre-embedding and SBF-SEM allowed visualization of cardiac Cx43 plaques in their native environment, providing for the first time a visual complement of functional data indicating the presence of orphan Cx43 hemichannels resulting from loss of desmosomal integrity in the heart.
AM1241-Loaded Poly(ethylene glycol)–Dithiothreitol Hydrogel Repairs Cranial Bone Defects by Promoting Vascular Endothelial Growth Factor and COL-1 Expression
Authors: Ai Yilong , She Wenting , Wu Siyuan , Shao Qing , Jiang Ziran , Chen Pengcheng , Mei Li , Zou Chen , Peng Youjian , He Yan 
Published: May 2022

Objective: To explore the repair effect of the prepared drug-loaded AM1241 poly(ethylene glycol)–dithiothreitol (PEG-DTT) hydrogel on cranial bone defects in SD rats.Methods: The PEG-DTT hydrogel under borax catalysis was quickly prepared, and the characterization of the material was observed by a scanning electron microscope. The effect of AM1241 on cell activity and bone tissue differentiation was tested. The SD rat model of cranial bone defect was established, and the defect was repaired by injecting the prepared hydrogel into the defect. The defect was divided into four groups, namely, sham group, blank group, PEG-DTT group, and PEG-DTT + AM1241 group. The rats were euthanized, and whole cranial bone was taken out for micro-CT and histological observation.Results: The prepared hydrogel is porous; it is liquid when heated to 80°C and a hydrogel when cooled to 25°C. 5–10 μM AM1241 increased osteoblast activity. A moderate amount of AM1241 can promote osteogenic differentiation. Both the PEG-DTT group and PEG-DTT + AM1241 group showed obvious new bone tissue formation, but the PEG-DTT + AM1241 group had a better effect. In addition, the new bone tissue in the PEG-DTT + AM1241 group was significantly more than that in the other groups.Conclusion: The prepared AM1241-loaded PEG-DTT hydrogel showed a good repair effect on SD rats with cranial bone defects. It can be used as materials for cranial bone repair in SD rats with cranial bone defects, but the repair effect is weaker than that of normal bone. These results provide a theoretical and practical basis for its further clinical application.
Design, Synthesis, and Apoptosis-Promoting Effect Evaluation of Rhopaladins’ Analog 4-Arylidene-5-Oxopyrrolidine Derivatives
Authors: Zhu Jun , Kong Ling-Qi , Chen Qin-Hua , Li Bin , Wu Lun , Ran Feng-Ying , Ke Li-Na , Zeng Xiao-Hua , Wang Hong-Mei 
Published: May 2022

Marine alkaloids have novel structures and antitumor activities. Therefore, we synthesized rhopaladins’ analogs from marine alkaloids rhopaladins A-D and modified their structures to synthesize 4-benzylidene-5-pyrrolidone derivatives. Among the compounds, (2E, 4E)-4-(4-chlorobenzylidene)-2-(4-chlorostyryl)-N-cyclohexyl-1-(4-fluorophenyl)-5-oxopyrrolidine-2-carboxamide (RPDPRH) has high efficiency and less hepatotoxicity, with IC50 values of 4.66, 6.42, 17.66, 15.2, 12.36, 22.4, and 243.2 μM in vitro anti-proliferative activity testing against cervical cancer C-33A, CaSki, SiHa, and HeLa cells, human hepatocarcinoma HepG2 and 7402 cells, and human normal liver LO2 cells, respectively. In particular, RPDPRH has similar activity to cisplatin on human hepatocarcinoma cells, and cisplatin served as a positive control in our study. Next, the apoptosis of HepG2 and 7402 cells induced by RPDPRH at different concentrations was detected by Annexin V/PI flow cytometry. Moreover, the expression of apoptotic proteins was detected by Western blot analysis. Finally, the results showed that RPDPRH could induce apoptosis of hepatocarcinoma cells by regulating Bax and Bcl-2 expressions. In summary, our results indicate that RPDPRH has the potential to serve as an antitumor agent and plays a significant role in future studies.
Sex Differences in the Outcomes of Cryoablation for Atrial Fibrillation
Authors: Hermida Alexis , Burtin Jacqueline , Kubala Maciej , Fay Floriane , Lallemand Pierre-Marc , Buiciuc Otilia , Lieu Audrey , Zaitouni Mustafa , Beyls Christophe , Hermida Jean-Sylvain 
Published: May 2022

BackgroundThe literature data on the outcomes of radiofrequency catheter ablation for atrial fibrillation (AF) in women are contradictory.AimTo determine and compare the outcomes and complications of cryoballoon pulmonary vein isolation (cryo-PVI) in men vs. women, and to identify predictors of atrial tachyarrhythmia (ATa) recurrence.MethodsWe included all consecutive patients having undergone cryo-PVI for the treatment of symptomatic AF in our center since 2012. Peri-operative complications were documented. All patients were prospectively monitored for the recurrence of ATa, and predictors were assessed.ResultsA total of 733 patients were included (550 men (75%) and 183 (25%) women). Paroxysmal AF was recorded in 112 (61%) female patients and 252 male patients (46%; p &lt; 0.001). Female patients were older (p &lt; 0.001) and had a greater symptom burden (p = 0.04). Female patients were more likely to experience complications (p = 0.02). After cryo-PVI for paroxysmal AF, 66% of the female patients and 79% of the male patients were free of ATa at 24 months (p = 0.001). Female sex was the only independent predictive factor for ATa recurrence (hazard ratio [95% confidence interval] = 1.87 [1.28; 2.73]; p = 0.001). After cryo-PVI for non-paroxysmal AF, 37% of the male patients and 39% of the female patients were free of ATa at 36 months (p = 0.73). Female patients were less likely than male patients to undergo repeat ablation after an index cryo-PVI for non-paroxysmal AF (p = 0.019).ConclusionA single cryo-PVI procedure for paroxysmal AF was significantly less successful in female patients than in male patients. Overall, the complication rate was higher in women than in men.
Estradiol and Hyperhomocysteinemia Are Linked Predominantly Through Part Renal Function Indicators
Authors: Niu Xiao Na , Wen He , Sun Nan , Yang Yi , Du Shi Hong , Xie Rong , Zhang Yan Nan , Li Yan , Hong Xiu Qin 
Published: May 2022

BackgroundPrevious studies have shown that estrogen, kidney function, and homocysteine (Hcy) or hyperhomocysteinemia (HHcy) are related to each other. However, the underlying biological mechanisms still remain unclear. We aimed to explore the association between estradiol (E2) and HHcy in the female population, and to further evaluate the mediating role of renal function indicators.MethodsThis unmatched case–control study consisted of 1,044 female participants who were 60.60 ± 12.46 years old. Data on general demographic characteristics, such as age, smoking and drinking status, menopause and so on were collected in a personal interview, and laboratory examinations were performed by well-trained personnel. The mediating effect model was applied to analyze the direct and indirect effects of E2 on Hcy.ResultsThe average levels of Hcy and E2 of the participants were 12.6 μmol/L and 14.95 pg/ml. There were statistical differences in renal indexes blood urea nitrogen (BUN), serum creatinine (Scr), uric acid (UA), glomerular filtration rate (GFR) and E2 between HHcy group and non-HHcy group. The logistic regression models showed that UA was risk factor for HHcy (P &lt;0.001), GFR and E2 were protective factors for HHcy after adjusting for confounding factors (P &lt;0.001). The indirect effects of E2 on Hcy through UA and GFR accounted for 14.63 and 18.29% of the total impacts of E2 on Hcy.ConclusionsThese data indicated that E2 was a protective factor of HHcy, and the effects of E2 on HHcy may be mediated by renal function indicators UA and GFR.
Placenta Accreta Spectrum Among Multiple Gestation: A Retrospective Analysis Based on a Chinese Population
Authors: Guo Zhirong , Han Xueyan , Zheng Weiran , Yang Huixia , Ma Jingmei 
Published: May 2022

BackgroundIt remained controversial whether women with multiple gestation are at higher risk of placenta accreta spectrum (PAS) disorders and large-scale studies are needed. This study aimed to assess whether PAS incidence is higher among women with multiple gestation than among singleton, as well as to compare the characteristics and outcomes of PAS in multiple and singleton gestation.MethodsWomen who underwent cesarean section with live births at Peking University First Hospital from January 2015 to December 2020 were included. Demographic and clinical information was collected through chart review. Logistic regression models were used to analyze the associations between multiple gestation and PAS. The clinical characteristics and perioperative outcomes of PAS in multiple and singleton gestation were further compared.ResultsAmong the 14583 women included, 2.4% (352/14583) were diagnosed with PAS. PAS was slightly more prevalent among multiple gestations than among singletons (2.5% vs 2.4%, P=0.857). After adjusting for known risk factors and pregnancy complications, multiple gestation was associated with a higher risk of PAS (aOR=1.63, 95% CI 1.01-2.62). Among PAS patients, women who had multiple births had a significantly lower rate of previous cesarean deliveries (27.6% vs. 56.3%, P=0.003), placenta previa (17.2% vs. 56.3%, P&lt;0.001) and invasive PAS (24.1% vs. 53.9, P=0.002) than singletons. There were no significant differences in perioperative outcomes between these two groups.ConclusionMultiple gestation could be independently associated with an elevated risk of PAS. The clinical characteristics of PAS in the multiple and singleton gestation groups differed significantly in cesarean delivery history and placenta previa. The results of this study may inform guidelines on the screening, early detection and timely intervention of PAS patients among women with multiple births.