bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prolonged Myocardial Regenerative Capacity in Neonatal Opossum
Authors: Nishiyama Chihiro , Saito Yuichi , Sakaguchi Akane , Kaneko Mari , Kiyonari Hiroshi , Xu Yuqing , Arima Yuichiro , Uosaki Hideki , Kimura Wataru 
Published: July 2022

Background:
Early neonates of both large and small mammals are able to regenerate the myocardium through cardiomyocyte proliferation for only a short period after birth. This myocardial regenerative capacity declines in parallel with withdrawal of cardiomyocytes from the cell cycle in the first few postnatal days. No mammalian species examined to date has been found capable of a meaningful regenerative response to myocardial injury later than 1 week after birth.

Methods:

We examined cardiomyocyte proliferation in neonates of the marsupial opossum (
Monodelphis domestica
) by immunostaining at various times after birth. The regenerative capacity of the postnatal opossum myocardium was assessed after either apex resection or induction of myocardial infarction at postnatal day 14 or 29, whereas that of the postnatal mouse myocardium was assessed after myocardial infarction at postnatal day 7. Bioinformatics data analysis, immunofluorescence staining, and pharmacological and genetic intervention were applied to determine the role of AMPK (5′-AMP–activated protein kinase) signaling in regulation of the mammalian cardiomyocyte cell cycle.

Results:
Opossum neonates were found to manifest cardiomyocyte proliferation for at least 2 weeks after birth at a frequency similar to that apparent in early neonatal mice. Moreover, the opossum heart at postnatal day 14 showed substantial regenerative capacity both after apex resection and after myocardial infarction injury, whereas this capacity had diminished by postnatal day 29. Transcriptomic and immunofluorescence analyses indicated that AMPK signaling is activated in postnatal cardiomyocytes of both opossum and mouse. Pharmacological or genetic inhibition of AMPK signaling was sufficient to extend the postnatal window of cardiomyocyte proliferation in both mouse and opossum neonates as well as of cardiac regeneration in neonatal mice.

Conclusions:
The marsupial opossum maintains cardiomyocyte proliferation and a capacity for myocardial regeneration for at least 2 weeks after birth. As far as we are aware, this is the longest postnatal duration of such a capacity among mammals examined to date. AMPK signaling was implicated as an evolutionarily conserved regulator of mammalian postnatal cardiomyocyte proliferation.
Frailty Status Modifies the Efficacy of Exercise Training Among Patients With Chronic Heart Failure and Reduced Ejection Fraction: An Analysis From the HF-ACTION Trial
Authors: Pandey Ambarish , Segar Matthew W. , Singh Sumitabh , Reeves Gordon R. , O’Connor Christopher , Piña Ileana , Whellan David , Kraus William E. , Mentz Robert J. , Kitzman Dalane W. 
Published: July 2022

Background:
Supervised aerobic exercise training (ET) is recommended for stable outpatients with heart failure (HF) with reduced ejection fraction (HFrEF). Frailty, a syndrome characterized by increased vulnerability and decreased physiologic reserve, is common in patients with HFrEF and associated with a higher risk of adverse outcomes. The effect modification of baseline frailty on the efficacy of aerobic ET in HFrEF is not known.

Methods:
Stable outpatients with HFrEF randomized to aerobic ET versus usual care in the HF-ACTION (Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training) trial were included. Baseline frailty was estimated using the Rockwood frailty index (FI), a deficit accumulation–based model of frailty assessment; participants with FI scores >0.21 were identified as frail. Multivariable Cox proportional hazard models with multiplicative interaction terms (frailty × treatment arm) were constructed to evaluate whether frailty modified the treatment effect of aerobic ET on the primary composite end point (all-cause hospitalization or mortality), secondary end points (composite of cardiovascular death or cardiovascular hospitalization, and cardiovascular death or HF hospitalization), and Kansas City Cardiomyopathy Questionnaire score. Separate models were constructed for continuous (FI) and categorical (frail versus not frail) measures of frailty.

Results:

Among 2130 study participants (age, 59±13 years; 28% women), 1266 (59%) were characterized as frail (FI>0.21). Baseline frailty burden significantly modified the treatment effect of aerobic ET (
P
interaction: FI × treatment arm=0.02; frail status [frail versus nonfrail] × treatment arm=0.04) with a lower risk of primary end point in frail (hazard ratio [HR], 0.83 [95% CI, 0.72–0.95]) but not nonfrail (HR, 1.04 [95% CI, 0.87–1.25]) participants. The favorable effect of aerobic ET among frail participants was driven by a significant reduction in the risk of all-cause hospitalization (HR, 0.84 [95% CI, 0.72–0.99]). The treatment effect of aerobic ET on all-cause mortality and other secondary endpoints was not different between frail and nonfrail patients (
P
interaction>0.1 for each). Aerobic ET was associated with a nominally greater improvement in Kansas City Cardiomyopathy Questionnaire scores at 3 months among frail versus nonfrail participants without a significant treatment interaction by frailty status (
P
interaction>0.2).

Conclusions:
Among patients with chronic stable HFrEF, baseline frailty modified the treatment effect of aerobic ET with a greater reduction in the risk of all-cause hospitalization but not mortality.
The Difficulty of Being a Marxist in Philosophy
Authors: Mozzachiodi Roberto Marino 
Published: July 2022

Abstract
This article seeks to locate Louis Althusser’s late preoccupation with the status of Marxists in philosophy through a survey of archival and marginal texts written on and amid struggles within the French education system. This material evidences that Althusser held a long-term ambition to reconcile the demands of being a Marxist in his professional life with the demands of being a philosopher in his political life. On this basis, this article offers an expanded contextualisation of the stakes that weighed upon Althusser’s shifting understanding and inhabitation of a Marxist position in philosophy. It aims to show that Althusser’s involvement with, and changing attitudes towards, the educational institution (and in particular the teaching of philosophy) played a significant role in forging the discontinuities in his conceptualisation of Marxist philosophy. The article additionally traces the afterlife of this practice in the work of Jacques Derrida and the Groupe de recherches sur l’enseignement de a philosophe (GREPH).
Negotiating Information under Conditions of High Asymmetry: An Exploration into the Domain of Interrogation
Authors: Faure Guy Olivier 
Published: July 2022

Abstract
The interrogation situation is a particularly asymmetric type of negotiation where the interrogated persons are prisoners and/or terrorists, having nothing more to lose because they know that their fate is already sealed. This type of relationship strictly responds to the definition of what is a negotiation, a process involving two or more parties to achieve a transaction. The objective of this article is to highlight the logic and techniques available to interrogators so that they succeed in establishing a form of exchange allowing them to gather strategic information, in particular when the parties to the conflict are engaged in open warfare. Five types of methods are distinguished and their effectiveness assessed: emotionally focused interrogation, morally based interrogation, manipulation, hard questioning, and extended object interrogation. Cases and examples are provided as illustrations.
Fair Trial for Victims Invoking Civil Claims: Rereading Αrticle 6(1) echr
Authors: Chioni-Chotouman Chara 
Published: July 2022

Abstract
The application of Article 6(1) echr under certain conditions in the case of the victim constitutes a distinct scope of application of the right to a fair trial. Even though the article applies only to the accused in its criminal aspect, it may apply in its civil one in criminal proceedings in the case of the civil party or any other procedural status inextricably linked to securing a civil claim. In this article, the exact scope of application for the victim will be examined alongside the extensive case-law of the ECtHR, which redefines the rights deriving from Art.6(1), revealing a new aspect of the right to a fair trial.
Celia’s Delighted Hips
Authors: Bariselli Michela 
Published: July 2022

Abstract
This article analyses the figure of Celia, questioning the description that emerges from the main account of Beckett’s early women. This account, originally developed by Bryden (1993), claims that women in Beckett’s early prose are represented through the filter of the male gaze, and are constructed in opposition to, and as an obstacle for, the male hero. This article argues that, in Murphy, the mechanisms set to reduce Celia to a stereotypical Woman, are foregrounded, and hence disrupted, by the presence of several contradicting perspectives, including Celia’s own perspective.
Manifestasi Ideologi dalam Terjemahan Item Taksa Al-Quran oleh Abdullah Basmeih
Authors: Kadir Kasyfullah Abd , Mansor Idris 
Published: July 2022

Abstract
Tafsir Pimpinan Al-Rahman (TPA) is the official Malay translation of the Quran. The government has worked on the translation ever since Malaya gained independence. Among the roles of TPA is to unite the Muslims in this country with one true belief. However, the Quran contains two types of meaning; the clear, direct verses as well as the ambiguous verses which are open for interpretations based on the translators’ ideologies. As such, the TPA is also subject to ideology-based interpretations of the translator. At the same time, the Muslims in Malaysia officially follow the Ahli Sunnah wal Jamaah and the Shafii School of belief. Therefore, this article reports on the findings from research carried out to examine the influence of the Ahli Sunnah wal Jamaah and Shafii School ideologies on the TPA translation of the Quran into Malay. Research data consists of ambiguous homonyms known as mushtarak. The research found that the TPA translation is in line with the belief and practice of the Malay Muslims in Malaysia who follow the Ahli Sunnah wal Jamaah and Shafii School of belief, through the selection of meanings consistent with the thought of the Shafii School, and the use of meaning interpretation approach to avoid resembling Allah with any creatures. This conforms to the Malaysian government’s policy on Islam.
Pemikiran Wasatiyyah Abdul Hadi Awang Mengenai Wacana Kenegaraan Menerusi Pentafsiran Al-Quran
Authors: Norasid Muhamad Alihanafiah bin , Abdullah Mustaffa bin , Amir Selamat bin 
Published: July 2022

Abstract
The idea of Moderation (Wasatiyyah) is believed to be a solution towards the unity of the people. This assertion of wasatiyyah is very significant in Malaysia which has a multi-ethnic population compared to other neighbouring countries. With the diversity of races and cultures in Malaysia, a harmonious life (al-Taʿāyush al-Silmi) needs to be manifested by displaying the wasatiyyah Approach from the Islamic worldview. Thus, this article aims to present the thoughts of an influential Malaysian leader and scholar, Tuan Guru Haji Abdul Hadi Awang in the discourse of nationhood in Malaysia. This study uses different methods including; descriptive method, content analysis method, interpretive thematic analysis method, and comparative analysis method. In order to reveal his moderate ideas from Islamic point of view, the author analyses his interpretation of the Quranic verses related to nationhood. The study significantly found that the issue of national discourse or nationhood presented by him respects the belief system, Islamic justice, and national unity and it is in line with the Quran and sunnah. The pattern of wasatiyyah manifested in his thinking helped the political system in Malaysia in strengthening the national unity among the plural society too.
A diverse assemblage of Miocene Lauraceae in Chalatenango, El Salvador
Authors: Vasquez-Loranca Alma Rosa , Cevallos-Ferriz Sergio R.S. 
Published: July 2022

Summary
The paleofloras of Central America are little known, and on this occasion, woods from the Miocene of Chalatenango, El Salvador, are reported. The identification was carried out from the elaboration of thin sections that allowed observation of anatomical patterns. Later, they were compared with woods of current and fossil taxa already described in the literature. The fossil specimens presented characteristics shared by several current genera of Lauraceae, so they were assigned to this family. However, since the variability of the woods between the genera of Lauraceae is low, it was uncertain to assign them to the current genera without having other plant organs. We recognize five new species in three fossil genera: Argapaloxylon salvadorensis, Laurinoxylon scalariforme, Mezilaurinoxylon miocenica, M. americana, and M. draconis. In addition, we assign a wood to an already described species, L. chalatenangensis. In Central America and southern Mexico, there is a great diversity and dominance of lauraceous plants in forests and jungles. The specimens described here represent new evidence suggesting that this vegetation type may have existed for approximately 15 million years. However, that current genera cannot be recognized even at this time is striking. A more detailed history of the lineages involved requires a closer comparison of existing plants with extinct ones.
The Roots of Culture
Authors: Choi Jung A , Kim Han Sung 
Published: July 2022

Abstract
Kim Suyŏng (1921–1968) is a Korean modernist poet whose works have been widely studied from the perspective of comparative and world literature. Yet, there is hardly any research on how his work is related to Russian literature. Given that he had little to no command of the Russian language, he used English translations to translate into Korean or comment on the Russian works selected for publication. His translations of Russian literature exhibit a consciousness of the characteristics of Russian literature, blended with Cold War English literature and post-colonial Korean literature. Referring to Pasternak’s poem “The Caucasus,” Kim noted that Pasternak’s journey in search of Russian roots was comparable to his pursuit of the “gigantic root” in post-colonial Korea. These two poets shared common ground in that both delved deep into tradition during the Cold War, when tradition was rejected as being reactionary.
Of Littérature-monde as an Untranslatable
Authors: Lejeune Nadège 
Published: July 2022

Abstract
In March of 2007 French newspaper Le Monde published the co-signed manifesto laying out the project of littérature-monde. Since then it has received much scholarly attention and has often been associated with its Anglophone counterpart, world literature. This article draws on Barbara Cassin’s concept of the untranslatable in the Vocabulaire européen des philosophies (2004) to complicate the project of littérature-monde: it needs to be articulated in relation to, rather than as a translation of, world literature. Following Cassin’s linguistic claim to a “maintien d’ une pluralité,” this article calls for contemporary literary scholarship to acknowledge littérature-monde and world literature as responses to different social, political, and cultural issues. Applying conceptual and philosophical untranslatability to the intrinsically different littérature-monde and to world literature destabilizes these fields’ global reach and consequently opens the possibility to consider them as co-existent, independent ways of reading literature on a global scale.
Woes of the True Global Novelist
Authors: Sotgiu Elisa 
Published: July 2022

Abstract
The global novel is one of the central stakes in the US-centered international literary field, a field that openly celebrates marginality, authenticity, and ethical bearing while still rewarding works targeted to an Anglophone, educated audience with an omnivorous aesthetic disposition. This essay reconstructs the genesis and the history of the contemporary literary field, tracing the geopolitical, social, and institutional changes that resulted in the current system of beliefs. The second part focuses on two celebrated global novelists, Elena Ferrante and Roberto Bolaño, studying the affinities in their work that reflect their similar position vis-à-vis the United States: they both disallow the centrality of the US and the legitimacy of academic institutions, make use of genre fiction, and craft their narratives around the figure of an authentic, marginal friend. These strategies prove to be particularly effective in responding to the contradictory constraints of the literary field.
Pachytylaradus cretaceous gen. et sp. nov. from Burmese amber (Heteroptera, Aradidae)
Authors: HEISS ERNST 
Published: July 2022

From the rich mid-Cretaceous amber deposits in Northern Myanmar, which yielded already numerous biological inclusions (Ross, 2019, 2021, 2022), to date the following nine genera of the heteropteran flat bug family Aradidae are recorded: Aradoleptus Heiss, 2016 (1 sp.); Archeaneurus Heiss, 2019 (1sp.); Archearadus Heiss & Grimaldi, 2001 (2 sp.); Archecalisius Heiss, 2019 (1sp.); Calisiomorpha Heiss 2016 (1sp.); Cretopiesma Grimaldi & Engel, 2008 (4 sp.); Ellenbergeria Heiss, 2016 (1sp.); Kachinocoris Heiss, 2012 (1sp.); Myanmezira Heiss & Poinar, 2012; (Heiss & Grimaldi, 2001; Grimaldi & Engel, 2008; Heiss, 2012, 2016, 2019a, b; Heiss & Poinar, 2012; Azar et al., 2020).
Impact of Haptic Cues and an Active Ankle Exoskeleton on Gait Characteristics
Authors: Wu Man I , Stegall Paul , Siu Ho Chit , Stirling Leia 
Published: July 2022

Objective This study examined the interaction of gait-synchronized vibrotactile cues with an active ankle exoskeleton that provides plantarflexion assistance. Background An exoskeleton that augments gait may support collaboration through feedback to the user about the state of the exoskeleton or characteristics of the task. Methods Participants ( N = 16) were provided combinations of torque assistance and vibrotactile cues at pre-specified time points in late swing and early stance while walking on a self-paced treadmill. Participants were either given explicit instructions ( N = 8) or were allowed to freely interpret (N=8) how to coordinate with cues. Results For the free interpretation group, the data support an 8% increase in stride length and 14% increase in speed with exoskeleton torque across cue timing, as well as a 5% increase in stride length and 7% increase in speed with only vibrotactile cues. When given explicit instructions, participants modulated speed according to cue timing—increasing speed by 17% at cues in late swing and decreasing speed 11% at cues in early stance compared to no cue when exoskeleton torque was off. When torque was on, participants with explicit instructions had reduced changes in speed. Conclusion These findings support that the presence of torque mitigates how cues were used and highlights the importance of explicit instructions for haptic cuing. Interpreting cues while walking with an exoskeleton may increase cognitive load, influencing overall human-exoskeleton performance for novice users. Application Interactions between haptic feedback and exoskeleton use during gait can inform future feedback designs to support coordination between users and exoskeletons.
A case report of otoendoscopic radiofrequency resection of squamous cell carcinoma of the external auditory canal
Authors: Liu Hong , Zhao Jing-Jing , Yang Hua 
Published: July 2022

Squamous cell carcinoma is the most common pathological type of external and middle ear malignancy. Squamous cell carcinoma of the external auditory canal and middle ear is closely associated with long-term chronic inflammatory irritation. The patient was admitted with a major complaint of a “stuffy feeling in the left ear for more than three months.” The results of the otoendoscopic examination were as follows: The left external auditory canal was filled with a granuloma-shaped mass with an unsmooth surface that showed obvious oozing of blood. The tympanic membrane was not visible. After the completion of the relevant examinations, radiofrequency resection of the external auditory canal mass was performed under otoendoscopy and the wound healed well with postoperative dressing changes. Pathological results revealed a well-differentiated keratinizing cutaneous squamous cell carcinoma and there was no recurrence throughout the next 5 years after the operation. Proper preoperative evaluation and the correct selection of surgical approaches can be of great importance. The primary complication of ear squamous cell carcinoma was local recurrence with a low incidence of metastasis. Early and complete resection was determined to be the optimal course of treatment.
The Construction and Embodiment of Dis/Ability for North Korean Refugees living in South Korea
Authors: Song Yosung , Freedman Justin E. 
Published: July 2022

Background/Context: Every year, an unknown number of North Koreans flee their homeland. As of 2020, 33,752 North Koreans had arrived in South Korea. The political positioning of North Korean refugees in South Korean society is unique from other immigrants, in that they receive immediate South Korean citizenship and are considered members of the same ethnic group as South Koreans. However, North Korean refugees face discrimination in South Korea, including in schools. Purpose/Objective/Research Question/Focus of Study: This paper extends the use of the intersectional analytical framework, disability critical race theory (DisCrit), outside of western settings to the Korean context. The purpose is to analyze the schooling experiences of North Korean refugees in South Korea. We provide a background about the divide between the nations of North and South Korea and discuss how this divide contributes to North Korean refugees’ position as outsiders. We also situate discrimination faced by North Korean refugees within South Korea as a broader response to changing demographics, by highlighting the experiences of immigrants and South Korean multicultural education policy. Drawing upon the voices of North Korean refugees, we analyze how the discrimination they experience constructs them as less capable and valued than their South Korean peers. Research Design: This paper reports the findings of a qualitative study that analyzes data from semi-structured interviews of North Korean refugees in South Korea. The interviews focus on participants’ schooling experiences in mainstream schools, at an alternative school, and in their transition to postsecondary education. Conclusions/Recommendations: Our analysis demonstrates how North Korean refugee students are positioned as dis/abled and come to embody disabling conditions as a result of discrimination based on their ethnicized North Korean identity in South Korea. The construction of North Korean refugees as dis/abled reflects the dominance of the ideals of South Korean ethnicity and an educational ideology that promotes assimilation for economic growth. We conclude by discussing the impact of normalizing processes of ethnocentrism, racism, and ableism, and the potential future development of multicultural education in South Korea.