bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Phenotypic Heterogeneity on Chemotactic Self-Organisation
Authors: Macfarlane Fiona R. , Lorenzi Tommaso , Painter Kevin J. 
Published: November 2022

AbstractThe capacity to aggregate through chemosensitive movement forms a paradigm of self-organisation, with examples spanning cellular and animal systems. A basic mechanism assumes a phenotypically homogeneous population that secretes its own attractant, with the well known system introduced more than five decades ago by Keller and Segel proving resolutely popular in modelling studies. The typical assumption of population phenotypic homogeneity, however, often lies at odds with the heterogeneity of natural systems, where populations may comprise distinct phenotypes that vary according to their chemotactic ability, attractant secretion, etc. To initiate an understanding into how this diversity can impact on autoaggregation, we propose a simple extension to the classical Keller and Segel model, in which the population is divided into two distinct phenotypes: those performing chemotaxis and those producing attractant. Using a combination of linear stability analysis and numerical simulations, we demonstrate that switching between these phenotypic states alters the capacity of a population to self-aggregate. Further, we show that switching based on the local environment (population density or chemoattractant level) leads to diverse patterning and provides a route through which a population can effectively curb the size and density of an aggregate. We discuss the results in the context of real world examples of chemotactic aggregation, as well as theoretical aspects of the model such as global existence and blow-up of solutions.
The bioeconomy and its untenable growth promises: reality checks from research
Authors: Eversberg Dennis , Holz Jana , Pungas Lilian 
Published: November 2022

AbstractThis paper starts out from the observation that recent official bioeconomy strategies and policy concepts are markedly more moderate in their promises of economic growth compared to the high-flying expectations of a ‘biotech revolution’ promoted around the turn of the millennium. We argue that this stepwise process of moderation is partly due to a series of ‘reality checks’ to which various strands of research on the bioeconomy have (willingly or unwillingly) subjected these promises, forcing governments to move away from visions exposed as unrealistic and to adopt more humble ones. We identify four such ‘reality checks’, originating from research on (a) bioeconomy discourses and knowledges, (b) contestation and power dynamics among actors and competing interests in bioeconomy politics and policymaking, as well as on (c) the economic and (d) biophysical dimensions of existing bio-based economies. In conclusion, we argue that bioeconomy research should adopt a broader perspective that considers transitions toward bio-based processes and resources as but one element in a comprehensive social–ecological transformation of current modes of production and living, and that understanding the dynamics of societal conflict around that transformation is crucial for assessing the social possibility of bioeconomy visions.
Lingering SARS-CoV-2 in Gastric and Gallbladder Tissues of Patients with Previous COVID-19 Infection Undergoing Bariatric Surgery
Authors: Hany Mohamed , Zidan Ahmed , Gaballa Muhammad , Ibrahim Mohamed , Agayby Ann Samy Shafiq , Abouelnasr Anwar Ashraf , Sheta Eman , Torensma Bart 
Published: November 2022

Abstract
Background
Lingering severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in gut tissue might be a source of infection during bariatric surgery. This study aimed to confirm the presence of SARS-CoV-2 nucleocapsid in gastric and gallbladder tissues removed during bariatric surgery in individuals previously infected with coronavirus disease 2019 (COVID-19) who had negative polymerase chain reaction results prior to the surgery.

Methods
Gastric and gallbladder specimens from 80 patients who underwent bariatric surgery between November 2021 and May 2022 and had a history of COVID-19 infection with gastrointestinal symptoms were examined for the presence of lingering SARS-CoV-2 nucleocapsid proteins using immunohistochemistry.

Results
Gastric specimens from 26 (32.5%) patients and 4 (100%) cholecystectomy specimens showed positive cytoplasmic staining for the anti-SARS-CoV-2 nucleocapsid protein in surface mucosal epithelial cells. The mean age was 37.8 ± 10.3 years. The average body mass index was 44.2 ± 7.0 kg/m2; most of the patients were females (71.3%). The positive staining group was significantly younger than the negative staining group (p = 0.007). The full-dose vaccination rate was 58.8%, with a median of 91 days after the last vaccine dose. A positive serological anti-spike IgG response was observed in 99% of the patients. The median time between initial COVID-19 infection and surgery was 274 and 380 days in the positive and negative staining groups, respectively (p = 0.371).

Conclusion
Gastric and gallbladder tissues can retain SARS-CoV-2 particles for a long time after COVID-19 infection, handling stomach specimens from patients during an operation must be done with care, as we usually do, but now with the knowledge that in 1/3 of patients they can be present. Performing LSG on post-COVID patients did not seem to increase perioperative morbidity.

Graphical Abstract
Lichen phycobiomes as source of biodiversity for microalgae of the Stichococcus-like genera
Authors: Chiva Salvador , Moya Patricia , Barreno Eva 
Published: November 2022

AbstractThe term phycobiome was recently introduced to designate all the microalgae (primary or non-primary) associated with lichen symbioses. Abundant non-primary symbiotic microalgae are usually obtained from lichen isolations, confirming that thalli are a source of biodiversity and new species. In this study, microalgae were isolated from thalli of Buellia zoharyi, Ramalina farinacea and Parmotrema pseudotinctorum collected in the Iberian Peninsula and the Canary Islands. Excluding Trebouxia phycobionts, 17 strains similar to Stichococcus (Prasiola clade) were obtained. Molecular identification was carried out by nuclear ITS sequencing, and a phylogenetic tree was generated from these sequences, and grouping them into 4 clades: Diplosphaera chodatti, Diplosphaera sp.1. Deuterostichocuccus sp.1. and Tritostichococcus coniocybes. It is also noteworthy that Diplosphaera sp.1 was detected and isolated from three phylogenetically distant lichenized fungi (B. zoharyi, R. farinacea and P. pseudotinctorum), which were sampled in ecologically different localities, namely Tenerife, La Gomera and Castellón. These results reinforce the idea of the constant presence of certain microalgae associated with the lichen thalli which, despite not being the main primary photobiont, probably form part of the lichen’s phycobiomes.
On the (Non-)Rationality of Human Enhancement and Transhumanism
Authors: Lyreskog David M. , McKeown Alex 
Published: November 2022

AbstractThe human enhancement debate has over the last few decades been concerned with ethical issues in methods for improving the physical, cognitive, or emotive states of individual people, and of the human species as a whole. Arguments in favour of enhancement defend it as a paradigm of rationality, presenting it as a clear-eyed, logical defence of what we stand to gain from transcending the typical limits of our species. If these arguments are correct, it appears that adults should in principle be able to make rational and informed decisions about enhancing themselves. In this paper, however, we suggest that a rational and informed choice to enhance oneself may in some cases be impossible. Drawing on L. A. Paul’s work on ‘transformative experience’, we argue that some enhancements—such as certain moral or cognitive modifications—may give rise to unbridgeable epistemic gaps in key domains. Importantly, such gaps could prove to be not merely contingently unbridgeable due to a lack of information at a given moment, but radically unbridgeable, making someone in a non-enhanced state inherently unable to conceive of what it would be like to be enhanced in a particular way. Where this experience is key to understanding what values are being pursued by the enhancement itself, it may prove impossible for a person to be sufficiently informed, and to make a rational decision about whether or not to enhance herself. This poses a challenge for human enhancement proponents in general, and for transhumanists in particular.
Numerical evaluation of the use of vegetation as a shelterbelt for enhancing the wind and thermal comfort in peripheral and lateral-type skygardens in highrise buildings
Authors: Mohammadi Murtaza , Tien Paige Wenbin , Calautit John Kaiser 
Published: November 2022

AbstractSkygardens or skycourts are a unique architectural intervention in the built environment, enhancing the social, economic, and environmental values of the building. It allows occupants to connect and experience outdoor freshness within a semi-enclosed environment. However, skygardens located on a highrise building may generate intense wind gusts, endangering the safety of occupants. Using a validated computational fluid dynamics model, this study investigates the potential of various vegetative barriers or shelterbelts in attenuating the high wind speeds encountered in such spaces and the impact on wind and thermal comfort. Three skygarden configurations were investigated with and without vegetative barriers, simplified and modelled as porous zones, and their effect was studied on the velocity and temperature profile at the occupants’ level. The results indicate that while hedges and trees can offer resistance to airflow, trees provide higher temperature reduction. However, a combination of vegetative and geometrical barriers provides the most optimal condition in the skygarden. The study has identified the importance of assessing wind attenuation characteristics of tree plantations on highrise skygarden, and the results can be used in designing intervention strategies. Moreover, vegetation can attenuate pollutants and mitigate poor air quality by surface deposition, and future studies should investigate in that direction.
De nieuwe volksgezondheidsexpert als gamechanger in een stevige preventie-infrastructuur
Authors: Fransen Gerdine , Pieters Moniek , Ter Bogt Maud , Mulder Geraldine , Mourits Kristine , Jonkman Harrie , Molleman Gerard , Hosman Clemens 
Published: November 2022

SamenvattingDe afgelopen decennia is vooral aandacht besteed aan het
ontwikkelen van de inhoud van het vak van preventie en
gezondheidsbevordering (GB). Er is nauwelijks geïnvesteerd in de
professional zelf en in voldoende professionals om preventie en
GB impact te laten hebben. De huidige complexe
volksgezondheidsproblemen vragen echter om kundige professionals
die weten hoe complexe vraagstukken aangepakt kunnen worden. De
gamechanger voor de volksgezondheid 2030 die wij voorstellen is een netwerk van een nieuw type volksgezondheidsexperts die vanuit een collectieve benadering en gesteund door een stevige preventiestructuur collectieve impact kunnen realiseren.
BAP1 in cancer: epigenetic stability and genome integrity
Authors: Caporali Sabrina , Butera Alessio , Amelio Ivano 
Published: November 2022

AbstractMutations in BAP1 have been identified in a hereditary cancer predisposition syndrome and in sporadic tumours. Individuals carrying familiar BAP1 monoallelic mutations display hypersusceptibility to exposure-associated cancers, such as asbestos-driven mesothelioma, thus BAP1 status has been postulated to participate in gene-environment interaction. Intriguingly, BAP1 functions display also a high degree of tissue dependency, associated to a peculiar cancer spectrum and cell types of specific functions. Mechanistically, BAP1 functions as an ubiquitin carboxy-terminal hydrolase (UCH) and controls regulatory ubiquitination of histones as well as degradative ubiquitination of a range of protein substrates. In this article we provide an overview of the most relevant findings on BAP1, underpinning its tissue specific tumour suppressor function. We also discuss the importance of its epigenetic role versus the control of protein stability in the regulation of genomic integrity.
Human-Robot Body Experience: An Artificial Intelligence Perspective
Authors: Beckerle Philipp 
Published: November 2022

AbstractHuman body experience is remarkably flexible, which enables us to integrate passive tools as well as intelligent robotic devices into our body representation. Accordingly, it can serve as a role model to make (assistive) robots interact seamlessly with their users or to provide (humanoid) robots with a human-like self-perception and behavior generation. This article discusses the potential of understanding human body experience and applying it to robotics. Particular focus is set on how to use artificial intelligence techniques and create intelligent artificial agents from insights about human body experience. The discussion is based on a summary of the author’s habilitation thesis and combines theoretical and experimental perspectives from psychology, cognitive science and neuroscience as well as computer science, engineering, and artificial intelligence. From this, it derives directions for future developments towards creating artificial body intelligence with human-like capabilities.
Experimental and Numerical Dynamic Behavior of Bending-Torsion Coupled Box-Beam
Authors: Patuelli Cesare , Polla Alessandro , Cestino Enrico , Frulla Giacomo 
Published: November 2022

Abstract
Purpose
Structural configurations related to new green aircraft design require high efficiency and low weight. As a consequence, moderate-to-large deformation under operating loads arise and aeroelastic instabilities different with respect to rigid counterpart are possible. Coupled structural configurations can provide the right mean to overcome such a critical situations selecting the right coupling parameters and structural performance. In this work, the dynamic behaviour of stiffened box-beam architecture with selected optimal stiffener orientation to emphasize the bending-torsion coupling characteristics has been investigated.

Methods
An extensive experimental activity has been performed for a validation and confirmation of the numerical results. Two cantilever beams produced with different technologies and materials have been tested. Modal performance has been determined by means of a laser Doppler vibrometer (LDV), while Finite-Element Method (FEM) numerical simulation based on solid elements and equivalent single layer approach have been applied and compared. Experimental/numerical comparison have been presented pointing out the specific coupling performance of this architecture with respect to natural frequencies and modal shapes.

Results
The activity demonstrates a good correlation in natural frequencies that remains mostly under 4$$\%$$
%
. Modal assurance criterion (MAC) has been considered in comparing experimental and numerical modal shapes.

Conclusion
The proposed innovative configuration demonstrates its capability to be used in aeroelastic critical problem as a mean to reduce their influence in aircraft design. The numerical procedure used for equivalencing the stiffened parts of the box-beam has also been validated in dynamical response confirming the possibility to be used in design phase.
Income, education, and hospitalization in Canada: results from linked census and administrative data
Authors: Godley Jenny , Tang Karen L. 
Published: November 2022

Abstract
Background
Addressing population health inequities begins with quantifying how social factors affect the health and health care utilization of individuals. Such quantification relies on the availability of detailed health and demographic data. Unfortunately, administrative health care data rarely includes detailed demographic information. Data linkage, which combines administrative health data with national-level census or survey data, enables researchers to examine socio-economic inequalities in health care utilization in greater detail.

Data and methods
With access to a unique Canadian dataset linking data from the Hospital Discharge Abstract Database (DAD) from 2006 to 2007 with detailed individual-level socio-demographic data from the 2006 Canadian Census, we are able to examine the patterning of hospitalization in Canada in the early 2000s across a variety of socio-demographic variables. We examine the association of education and income, controlling for immigration status, rural residence, marital status and ethnicity, with hospitalization rates for both ambulatory care sensitive conditions (ACSCs) and non-ambulatory care sensitive conditions (non-ACSCs) for children and youth, working-age adults, and older adults, in models stratified by sex.

Results
Age standardized hospitalization rates show that there is a clear socio-economic gradient in hospitalization in Canada in the 2000s. Education and income are independently, inversely associated with hospitalization for males and females across three broad age groups. These associations are stronger for ACSCs than non-ACSCs. The association of other socio-demographic variables, such as immigrant status, and rural residence is also stronger for hospitalization for ACSCs. The association of socio-economic status with hospitalization for ACSCs is strongest for working age women and men, and is somewhat attenuated for older adults.

Conclusions
Lower socio-economic status is associated with a higher likelihood of hospitalization for men and women in Canada across three broad age groups in the 2000s. These associations are stronger for ACSCs, suggesting that in addition to increased likelihood of disease, decreased access to preventative care may be driving up hospitalization rates for marginalized groups. We conclude with the recommendation that in order to track progress in reducing health inequities, health systems should either collect detailed individual-level socio-demographic data or link their administrative health data to existing demographic data sets.
The Arid Regolith of the Moon
Authors: Hodges R. R. , Farrell W. M. 
Published: November 2022

AbstractIn the original hypothesis of ice in lunar polar cold traps, it was presumed that meteoritic water acquired by the lunar surface would be concentrated in cold traps by exospheric lateral transport. That supposition is proven to be false by the absence of evidence of exospheric water in data obtained by the neutral mass spectrometer on the Lunar Atmosphere and Dust Environment Explorer (LADEE) spacecraft. The upper limit for exospheric water at the lunar surface, ∼3 molecules cm−3, is deficient by several orders of magnitude in accounting for transport of the present influx of meteoritic water to cold traps. The proffered process for removal of meteoritic water from the lunar regolith is solar wind sputter. This LADEE result does not rule out the possibly of past impulsive exospheric events like cometary impacts but does place a rigid constraint on the modern day water cycling.
Nonlinear Earthquake Response of Marine Sediments With Distributed Acoustic Sensing
Authors: Viens Loïc , Bonilla Luis Fabian , Spica Zack J. , Nishida Kiwamu , Yamada Tomoaki , Shinohara Masanao 
Published: November 2022

AbstractSoft sediment layers can significantly amplify seismic waves from earthquakes. Large dynamic strains can trigger a nonlinear response of shallow soils with low strength, which is characterized by a shift of resonance frequencies, ground motion deamplification, and in some cases, soil liquefaction. We investigate the response of marine sediments during earthquake ground motions recorded along a fiber‐optic cable offshore the Tohoku region, Japan, with distributed acoustic sensing (DAS). We compute AutoCorrelation Functions (ACFs) of the ground motions from 105 earthquakes in different frequency bands. We detect time delays in the ACF waveforms that are converted to relative velocity changes (dv/v).dv/vdrops, which characterize soil nonlinearity, are observed during the strongest ground motions and exhibit a large variability along the cable. This study demonstrates that DAS can be used to infer the dynamic properties of the shallow Earth with an unprecedented spatial resolution.
Challenging Radiocarbon Chronostratigraphies in Central Arctic Ocean Sediment
Authors: Hillaire‐Marcel C. , de Vernal A. , Rong Y. , Roberge P. , Song T. 
Published: November 2022

AbstractBased on the analysis of fish otolith assemblages from surface sediments of the Lomonosov Ridge (Arctic Ocean), we demonstrate that the very low Holocene sedimentation rates and winnowing of fine sediments result in the mixing of the whole Holocene populations at the sediment surface. Specimens from the Marine Isotope Stage (MIS) 3 or older could even be recovered in the surface due to a sedimentary hiatus at some locations in the central Arctic during the last glacial maximum. Two examples illustrate that 14C‐stratigraphies from planktic foraminifers in underlying cored sediments reflect the mixing between Holocene and MIS 3 or older populations, thus invalidating continuous age‐depth inferences based on 14C ages. Hence, much caution is required when attempting to set paleoceanographic reconstructions based on 14C chronologies in a low sediment accumulation rate environment such as the central Arctic Ocean. Already published paleoceanographic reconstructions from this area might thus require some revisions.
Simultaneous Cross‐Energy Ion Response and Wave Generation After the Impact of an Interplanetary Shock
Authors: Li Yu‐Xuan , Yue Chao , Ma Qianli , Liu Jianjun , Zong Qiu‐Gang , Zhou Xu‐Zhi , Hu Zejun , Li Li , Ren Jie , Wang Yong‐Fu , Liu Ying 
Published: November 2022

AbstractInterplanetary (IP) shocks have substantial impact on particles and electromagnetic fields when arriving at the Earth's magnetosphere. In this study, we have examined the dynamics of cross‐energy ions and plasma waves observed by Van Allen Probe B near the equator at the noon sector inside the geosynchronous orbit after the impact of an IP shock on 27 February 2014. We found that the Ultra‐Low Frequency (ULF) and electromagnetic ion cyclotron (EMIC) waves are induced, and the differential fluxes of protons of various energies have different responses after the IP shock arrival. The perpendicular flux increased dramatically for low‐energy ions (10–100 eV) due to the electric field drift and betatron acceleration. These adiabatic processes also accounted for the evident proton flux decrease at 30–80 keV energies and increase at energies higher than 100 keV, caused by the positive or negative gradient in phase space density before the IP shock arrival. The short‐lived ULF waves triggered by the IP shock also interacted with the ∼100 keV protons, resulting in the stripes in their pitch angle distribution. The anisotropic distribution of >50 keV protons excited EMIC waves after the shock arrival. This study provides a comprehensive picture of the IP shock effects on the ions of different energies and plasma waves inside the geosynchronous orbit, which shed new lights on the cross‐energy responses of ions and plasma waves in the inner magnetosphere to solar wind discontinuities.