bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efeito da corrida de rua na qualidade de vida: um estudo descritivo e exploratório
Authors: Santos Ivoneide Firmino dos , Araújo Matheus Cardoso de , Santos Walmir Romário dos , Costa Marlene Salvina Fernandes da , Santos Wlaldemir Roberto dos 
Published: October 2022

Objetivo: verificar a influência da corrida de rua na qualidade de vida. Métodos: trata-se de um estudo transversal, descritivo, com delineamento exploratório, do tipo survey, que observou 118 praticantes de corrida de rua, selecionados de forma não-probabilística e por conveniência. Onde foi aplicado um questionário sociodemográfico, semiestruturado, para a descrição dos participantes, e para verificar a qualidade de vida, foi aplicado o questionário SF-36. A normalidade dos dados foi verificada aplicando o texto Shapiro Wilk, homogeneidade pelo teste de Levene’s (distribuição normal). Os valores foram apresentados em média e desvio padrão para caracterização da amostra geral e por gênero. Todos os testes foram realizados a partir do SPSS Versão 20.0. Resultados: Não foram observadas diferenças significativas da qualidade de vida entre os gêneros. O tempo de prática apresentou correlação significante com a capacidade funcional (p=0,001) e a redução da limitação dos aspectos físicos (p=0,005). Conclusão: A corrida de rua apresenta um importante impacto na qualidade de vida dos praticantes, quando realizada de modo regular. Os benefícios extrapolam o âmbito biodinâmico, gerando benefícios em variáveis psicossociais.
Comparação do VO2 de pico relativo e alométrico em adolescentes sob diferentes condições de treinamento de Futebol de campo
Authors: Cambiaghi Rodrigo , Hespanhol Jefferson Eduardo , Lopes Charles Ricardo , Cossio-Bolaños Marco , Gomez-Campos Rossana , De Moraes Anderson Marques 
Published: October 2022

O consumo máximo de oxigênio (VO2pico) é utilizado em estudos com adolescentes para relacionar a aptidão física ao estado de saúde, e, na área do treinamento esportivo, para a prescrição e avaliação de programas de treinamento. O objetivo do presente estudo foi verificar o VO2pico em adolescentes praticantes de Futebol de campo observando o tipo de treinamento e o tamanho corporal. A amostra foi composta por 116 adolescentes masculinos, idade entre 12 e 15 anos, divididos em três grupos, o Grupo Controle (GC; n=45), o Grupo de Esporte Educacional (GEE; n=45) e o Grupo de Atletas de Futebol (GAF; n=26). Foram avaliadas a estatura e a massa corporal. O Yo-Yo Intermittent Endurance Test foi utilizado para avaliar o VO2pico. Foi utilizada a ANOVA (one way), para determinar as diferenças intergrupos. O VO2pico foi ajustado alometricamente pelo expoente de -0,67. Inicialmente observou-se melhor desempenho aeróbio do grupo GEE em relação ao GED. Após o ajuste alométrico, os resultados apontaram para o melhor desempenho do GAF em relação ao GED e GEE. Conclui-se que para se avaliar o VO2pico em adolescentes é necessário levar-se em conta, não só o tipo de treinamento utilizado (volume e intensidade), mas também o seu tamanho corporal.
Radiation induced radionecrosis
Authors: Ilknur 1 Alsan Cetin , Ozum 2 Tuncyurek , Ozsunar 2 Dayanır 
Published: October 2022

Radiotherapy (RT) in cancer treatment is a standard approach. Radiation necrosis (RN) may occur as late side effects of radiotherapy. It is difficult to detect. The main dilemna is the differential diagnosis of recurrence and necrosis. Because of this, cutting edge technological improvements are usually applied for reliable diagnosis of the remnant brain lesion. Those include perfusion, diffusion and spectroscopic MRI examination. Conventional and advances radiological techniques were compared. In this study we aimed to investigate causes of radionecrosis, diagnosis and treatment.
A second thought on low lying pubic tubercle -can inguinal hernia occurrence be predicted?
Authors: Saldanha Elroy , D’Cunha Rithesh Joseph , D’Souza Reshmina C.C , Fernandes Shannon , Rao Shubha 
Published: October 2022

Introduction: Among all hernias inguinal hernia is known to be the most common condition for which surgery is being performed and 75% of all hernia occur in groin.The low pubic tubercle has more tendencies for herniation due to unusual origin of internal oblique muscle leaving internal ring unprotected during abdominal muscle contraction. In view of this we conducted a study to evaluate the incidence of inguinal hernia in low lying pubic tubercle and its correlation with occurrence of inguinal hernia.Materials and methods: A Hospital based prospective study was be conducted on 100 patients, who came with inguinal hernia conducted from May 2015 to April 2018 at Father Muller Medical College Hospital and those who met the criteria. Plain Anteroposterior Radiographs of Pelvic region in 100 patients of inguinal hernia and to find out if low lying pubic tubercle has any correlation with occurrence of inguinal herniaResults: A total of 100 patients with inguinal hernia meeting the inclusion criteria was included in the study, plain X-ray of the pelvis was taken to measure SS (Distance between each anterior superior iliac spines) and ST (Spinotubercular) line and we found that 76 patients out of 100 (76.0%) patients with inguinal hernia had a low lying PT that is ST >7.5 cms. 78 patients had indirect inguinal hernia and 32 patients had direct inguinal hernia.In our study of groin hernias, the most common age group involved is the 41-50 years age group with 17 cases 42.5%. The mean age in our study was is 47.05 years Standard deviation of age is 12.15years. In our study of groin hernias, the most common gender involved in groin hernias was male with 38 cases 95% of the cases.
Bacteria on surfaces contacted during intraoral radiographic examinations
Authors: Lee Guihan , Calderón-Ubaquí Victor , Sacsaquispe-Contreras Sonia 
Published: October 2022

Objective: To determine the presence of bacteria by means of microbiological analysis on the surfaces contacted by the operator during the taking and processing of intraoral radiographs at different times of the day in the Oral Radiology Service of the UPCH. Materials and methods: Nine surfaces of the oral radiology service were sampled. The samples were taken at two times by the same investigator; at the beginning and the end of the activities in the service, the surfaces were swabbed with Trypticase Soy Broth (TSB). The samples were inoculated and incubated in three culture media (Plate Count Agar, Lamb’s Blood Agar and Cetrimide Agar). Then the respective Colony Forming Unit (CFU) count was performed and Gram staining was also performed. Results: A high concentration of bacteria (4180 CFU/mL) and fungi was found in the oral radiology service. Gram-positive cocci were the most frequently found microorganisms and gram-negative bacilli were less frequently found. Conclusions: There is a high contamination of bacteria in the oral radiology service. When the activities are completed, the number of bacteria decreases, but the variety of bacteria increases.
Doppler-echo guided angioplasty in the treatment of arterio-venous fistula stenosis for hemodialysis
Authors: Torres Eduardo Mateos , Joan Meritxell Mellado , Juscafresa Laura Calsina , Carmona Carlos Ruiz , Velasco Albert Clará 
Published: October 2022

Introduction: Stenoses in the path of arteriovenous fistulas (AVF) for hemodialysis are a very prevalent problem and there is long experience in their treatment by percutaneous angioplasty (PTA). These procedures, however, involve non-negligible equipment requirements, exposure to radiation and intravenous contrast that are not beneficial for the patient and make their performance more complex. This study reviews our initial experience with Doppler ultrasound-guided angioplasty. Methods: Prospective cohort of patients with native AVF dysfunction due to significant venous stenosis treated by Doppler echo-guided PTA. AVF puncture, lesion catheterization, balloon localization and inflation, and outcome verification were performed under ultrasound guidance. Only one fistulography was performed before and another one after dilatation. As a control, the cases performed during the same period by the usual angiographic method were also collected. Results: Between February 2015 and September 2018, 51 PTAs were performed on native AVF, of which 27 were echogenic (mean age, 65.3 years; 63% male). The technical success rate was 96%. In 26% of cases, PTA was repeated due to residual stenosis after angiographic imaging. There were 7.3% periprocedural complications. 92% of the AVFs were punctured at 24 hours. Primary patency at 1 month, 6 months and 1 year was 100%, 64.8% and 43.6%, and assisted patency was 100%, 87.2% and 74.8%. There were no significant differences in immediate or late results with respect to angiographically guided AVF angioplasty. Conclusions: AVF-PTA can be performed safely and effectively guided by Doppler ultrasound, which simplifies the logistics required for its performance, although we still need to improve the capacity for early verification of the result with this imaging technique.
Topographic evaluation of sacroiliac joints by magnetic resonance imaging in patients with axial spondyloarthritis
Authors: Aivazoglou Laís Uyeda , Zotti Orlando Rondan , Pinheiro Marcelo de Medeiros , De Castro Junior Moacir Ribeiro , Puchnick Andrea , Fernandes Artur da Rocha Corrêa , De Ávila Fernandes Eloy 
Published: October 2022

Objective: To evaluate the imaging features of spondyloarthritis on magnetic resonance imaging (MRI) of the sacroiliac (SI) joints in terms of topography (in thirds) and affected margin, since this aspect is rarely addressed in the literature. Methods: Cross-sectional study with MRI (1.5 T) evaluation of the SI in 16 patients with diagnosis of axial spondyloarthritis regarding the presence of acute (subchondral bone edema, enthesitis, synovitis and capsulitis) and chronic changes (erosions, subchondral bone sclerosis, bone bridging and fatty replacement), performed by two radiologists, blinded to clinical data. MRI findings were correlated with clinical data including age, disease duration, medications, HLA-B27, BASDAI, ASDAS-VHS and ASDAS-PCR, BASMI, BASFI, and mSASSS. Results: Bone edema pattern and erosions showed predominance in the upper third of SI (p = 0.050, p = 0.0014, respectively). There was a correlation between the time of disease and structural changes by affected third (p = 0.028-0.037), as well as the presence of bone bridges with BASMI (p = 0.028) and mSASSS (p = 0.014). Patients with osteitis of the lower third had higher ASDAS values (ESRV: p = 0.011 and CRP: p = 0.017). Conclusion: Chronic inflammatory changes and the pattern of bone edema predominated in the upper third of the SI, but there was also concomitant involvement of the middle or lower thirds of the joint. The localization of involvement in the upper third of the SI was insufficient to differentiate between degeneration and inflammation.
Magnetic resonance imaging: Recent research on the biological impacts of static magnetic and high-frequency electromagnetic fields
Authors: Pophof Blanka , Brix Gunnar 
Published: October 2022

Problem: in recent years, new studies have been published on biological effects of strong static magnetic fields and on thermal eﬀects of high-frequency electromagnetic fields as used in magnetic resonance imaging (MRI). Many of these studies have not yet been incorporated into current safety recommendations. Method: scientific publications from 2010 onwards on the biological effects of static and electromagnetic fields of MRI were searched and evaluated. Results: new studies confirm older work that has already described effects of static magnetic fields on sensory organs and the central nervous system accompanied by sensory perception. A new result is the direct effect of Lorentz forces on ionic currents in the semicircular canals of the vestibular organ. Recent studies on thermal effects of radiofrequency fields focused on the development of anatomically realistic body models and more accurate simulation of exposure scenarios. Recommendation for practice: strong static magnetic fields can cause unpleasant perceptions, especially dizziness. In addition, they can impair the performance of the medical personnel and thus potentially endanger patient safety. As a precaution, medical personnel should move slowly in the field gradient. High-frequency electromagnetic fields cause tissues and organs to heat up in patients. This must be taken into account in particular for patients with impaired thermoregulation as well as for pregnant women and newborns; exposure in these cases must be kept as low as possible.
From standard radiography to whole-body MRI: 30 years of progress in multiple myeloma imaging
Authors: Lecouvet Frédéric , Berg Bruno Vande , Malghem Jacques , Maldague Baudouin , Ferrant Augustin , Michauxu Jean-Louis 
Published: October 2022

Multiple myeloma (MM) is a hematologic cancer characterized by clonal proliferation of plasma cells within the bone marrow. It is the most serious form of plasma cell dyscrasias, whose complications—hypercalcemia, renal failure, anemia, and lytic bone lesions—are severe and justify the therapeutic management. Imaging of bone lesions is a cardinal element in the diagnosis, staging, study of response to therapy, and prognostic evaluation of patients with MM. Historically, the skeletal radiographic workup (SRW), covering the entire axial skeleton, has been used to detect bone lesions. Over time, new imaging techniques that are more powerful than SRW have been evaluated. Low-dose and whole-body computed tomography (CT) supplants SRW for the detection of bone involvement, but is of limited value in assessing therapeutic response. Bone marrow MRI, initially studying the axial pelvic-spinal skeleton and more recently the whole body, is an attractive alternative. Beyond its non-irradiating character, its sensitivity for the detection of marrow damage, its capacity to evaluate the therapeutic response and its prognostic value has been demonstrated. This well-established technique has been incorporated into disease staging systems by many health systems and scientiﬁc authorities. Along with positron emission tomography (PET)-18 ﬂuorodeoxyglucose CT, it constitutes the current imaging of choice for MM. This article illustrates the progress of the MRI technique over the past three decades and situates its role in the management of patients with MM.
Zoltán Vámossy, versatile and active medical professor of the Institute of Pharmacy
Authors: Mária Péter H. 
Published: October 2022

Abstract
Zoltán Vámossy (1868–1953), with Transylvanian roots, became a doctor 130 years ago, in 1891, at the University of Budapest. Later, from 1898, he was appointed a private university professor of Pharmacology, from 1908 a public university professor, and from 1920 to 1938 he was director of the Institute of pharmacology. In the meantime, from 1922 to 1924, he also held the position of dean of the Faculty of Medicine. He was elected a corresponding member of the Hungarian Academy of Sciences on May 5, 1920, but on April 23, 1948 his membership was terminated for political reasons. It was not restored until after his death, on 9 May 1991. Afterwards he taught even in the 1945/46 school year. He was an understanding and helpful instructor for the university students, so he was respected, appreciated, and loved. His professional life was filled with university education, academic work, and editorial duties. He wrote books to promote education, for example he translated into Hungarian a book written by Arnold Cloetta and Wilhelm Filehne in 1881, entitled Lehrbuch der Arzneimittellehre und Arzneiverordnungslehre. This was published in 1894 in Budapest under the title Gyógyszertan tankönyv (Pharmacology Textbook). In 1907 he published his own book Mérgezésekről (On Poisonings), and in 1908 Gyógyszertan orvostanhallgatók és orvosok számára (Pharmacology for medical students and physicians). The latter’s ninth, expanded and revised edition appeared in 1944. Medical students in Hungary and Transylvania learned from this for decades. In 1933 he was appointed chairman of the editorial board of the IV. Magyar Gyógyszerkönyv. His editorial work is also significant. From 1909 to 1944 he was the commissioned editor of the new course of the Magyar Orvosi Archivum (Hungarian Medical Archive), and from 1923 to 1944 he was the editor-in-chief of the Orvosi Hetilap (Medical Weekly). During this time, many of his writings were published here. In December 1927 issue, he announced that certain issues of the Orvosi Hetilap would be supplemented by a permanent supplement entitled Az Orvosi Gyakorlat Kérdései (Questions of Medical Practice). In 1940, in parallel with the Medical Weekly, he founded the monthly Orvostudományi Közlemények (Medical Gazette), which was published until the end of 1944. He strived for the correct use of the Hungarian medical language in all his writings..
Chemical and pharmacological characterization of anthelmintic benzimidazoles
Authors: Hajnal Kelemen , Edina Mărcuțiu Petra , Adrienn Rausz , Lajos-Attila Papp 
Published: October 2022

Abstract
Benzimidazoles, which interfere with the complex life cycle of worms, are essential in the treatment of helminthiasis. Four benzimidazole antihelmintics have been used in human therapy: albendazole, mebendazole, thiabendazole, triclabendazole. The history, representatives, synthesis, physicochemical properties, structure-activity relationships of anthelmintic benzimidazoles are presented in the review, as well as the pharmacological properties and mechanism of action of these agents.
In the last decade, benzimidazole carbamate-structured anthelmintics have also been studied for their antitumor activity.
Cyclodextrin-based nanofibers obtained by electrospinning
Authors: Pálma Bucur , Ibolya Fülöp , Emese Sipos , Zoltán-István Szabó 
Published: October 2022

Abstract
The aim of our research was to prepare polymer-free hydroxypropyl-β-cyclodextrin-(HPβCD) and sulfobutylether-β-cyclodextrin (SBEβCD) based nanofibers. For this purpose, four-four viscous, aqueous solutions were prepared with different concentrations from each cyclodextrin derivative, with the following concentrations: 170, 180, 190 and 200% (v/w) from HPβCD and: 210, 220, 230 and 240% (v/w) from SBEβCD.
The parameters for the electrospinning process were: 1.5 ml/h flowrate, 22-24 G sized needle, and an applied voltage of 25 kV. The distance between the needle and the collector was 13-15 cm in the case of HPβCD, and 9-11 cm in the case of SBEβCD.
The obtained nanofibers were morphologically characterized and their dis-integration process was also tracked. Then, the results obtained were compared within each cyclodextrin group, in order to identify optimal spinning parameters and they were also discussed, based on previous reports.
From our results, we concluded that the 200% HPβCD solution is the most effective for nanofiber formation, producing smooth, homogenous fibers with small diameters, which present ideal disintegration properties. At the tested voltages, it was not possible to form ideal nanofibers from SBEβCD, however, we managed to form some nanofibers with acceptable quality, and the ones made out from the 240% solution of the SBEβCD were the most suitable.
Importance of Population Education in Implementation of Compulsory Immunization Against Polyomyelitis in Children
Authors: Joncic Tijana S. , Jovanovic Mirkovic Jasmina M. , Velic Selena D. , Alexopoulos Christos G. , Jurinjak Zorana Z. 
Published: October 2022

Abstract
Poliomyelitis is a contagious disease characterized by the appearance of fever, malaise, scratching in the throat, gastrointestinal signs, and after a few days the appearance of muscle paralysis, as well as respiratory and vasomotor disorders. Today, this disease is very rare, due to systemic active immunization. The aim of this study was to assess the level of knowledge and attitudes toward poliomyelitis and importance of immunization against it.
A specially designed survey questionnaire was used for interviewing purposes. Data analysis and processing were performed using a statistical data processing package (SPSS for Windows, version 20). A chi-square test was used from the statistical tests.
The educated profile of the respondents was as follows: medical sciences - 37 (50%), natural sciences and mathematics - 6 (8,1%), social sciences - 5 (6,8%), technical sciences - 19 (25,7%) and arts - 7 (9,5%). The study findings indicate a high level of awareness and knowledge of the population regarding polio, as well as good health awareness of the population about immunization i.e. polio vaccination. 34 respondents from the field of medical education answered the question exactly how the vaccine protects against the disease. In the field of natural mathematical sciences, a total of 3 gave the correct answer, which makes 50% of the total number of persons (6) in the mentioned field. In addition, majority of the study sample (70,3%) is aware that child should be vaccinated. Furthermore, 91,9% of respondents agree that education of parents regarding children vaccination is of great importance for whole community.
Based on findings of present study it can be concluded that efforts still need to be made in education of the wider population toward polio and the importance of vaccination. In addition to healthcare professionals, the entire community should participate in this strategic task.
The Role of Galectin 3 in the Pathogenesis of Diabetes Mellitus: Focus on Β-Cell Function and Survival
Authors: Marinkovic Milos , Petrovic Ivica 
Published: October 2022

Abstract
Galectin 3 is a lectin expressed in many tissues with a significant biological role in physiological and pathological processes. Our review aims to sublimate the effects of galectin 3 on the β-cells function and survival. Data about the effect of galectin 3 on β- cells are scarce and contradictory. Several studies have shown that reduced activity of the galectin 3 gene reduces the risk of developing type 1 diabetes in an experimental model of diabetes in galectin 3 deficient mice. On the other side, in an experimental model of type 1 diabetes with mice with selectively enhanced expression of galectin 3 in β-cells, was shown that increased expression of this lectin has a protective role. Unlike type 1 diabetes where the autoimmune process plays a dominant role in pathogenesis, the pathogenesis of type 2 diabetes is multifactorial. One of the main factors which contribute to type 2 diabetes, the insulin resistance, is related to the concentration of soluble galectin 3. The effect of galectin 3 is very important for β-cell function. When a harmful factor acts on a β-cell, its intracellular concentration increases to preserve the function of β-cells and prevent their apoptosis, by blocking the internal path of apoptosis. However, excessive accumulation of galectin 3 inside the cell leads to its secretion, which encourages tissue inflammation. Based on all the above, galectin 3 has a double effect on β-cells.
FOREIGN VESSEL SINKING POLICY IN ERADICATING ILLEGAL, UNREPORTED, AND UNREGULATED (IUU) FISHING IN THE INDONESIAN EXCLUSIVE ECONOMIC ZONE (IEEZ)
Authors: Khalik Richard Al , Roesa Nellyana 
Published: October 2022

The relevance of foreign vessel sinking policy to eradicate IUU fishing in IEEZ by national regulation to UNCLOS 1982 is questionable. This paper uses a normative legal analysis, examining international conventions and national regulation provisions and their application to legal events. The results indicate that implementing the foreign vessel sinking policy is national law enforcement of Law No. 45 of 2009 amendment to the Law No. 31 of 2004 Concerning Fishery, Article 69 (1) and (4). The foreign vessel sinking policy is not contrary to UNCLOS 1982 because the subject protected in EEZ by Article 73 (3) is the human being, not the vessel. It remains an effective means to create a deterrent effect as an optimum penalty for such crime.