bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between social support, anxiety, and depression among frontline healthcare workers in China during COVID-19 pandemic
Authors: Zhan Jie , Chen Chen , Yan Xiaoting , Wei Xiaojing , Zhan Lechang , Chen Hongxia , Lu Liming 
Published: September 2022

BackgroundSocial support is an important factor affecting individual mental health. However, the relationship between social support and mental health in frontline healthcare workers (FHW) during the coronavirus disease 2019 (COVID-19) pandemic has garnered less attention. In this study, we aimed to investigate the level of social support and the prevalence of depression and anxiety in FHW during the COVID-19 pandemic and determine the factors affecting the relationship between social support, depression, and anxiety.MethodsA cross-sectional study using an online survey was conducted to collect data from FHW between 15 February and 31 March 2020 in China. The data included demographic factors, Self-rated Depression Scale (SDS), Self-rated Anxiety Scale (SAS), and Social Support Rate Scale (SSRS). Spearman correlation test was performed to determine the correlation among SAS, SDS, and SSRS scores. Multiple linear regression analysis was performed to determine the relationship among demographic factors, social support, depression, and anxiety in FHW.ResultsOf all 201 participants, 44 (21.9%) had depressive symptoms and 32 (15.9%) had anxiety symptoms. The average total SSRS scores among FHW were lower than that of the norms of the Chinese general population (37.17 ± 7.54 versus 44.38 ± 8.38, P &lt; 0.001). Marital status positively affected the SSRS score (β = 7.395, P &lt; 0.01). Age over 40 years old negatively affected the SSRS score (β = −5.349, P = 0.017). The total SSRS score, subjective social support score, objective social support score, and support utilization score among FHW negatively correlated with the SAS score and SDS score (P &lt; 0.05). A lower support utilization score was significantly associated with high anxiety and depressive symptoms (β = −0.869, P = 0.024; β = −1.088, P = 0.035, respectively).ConclusionDuring the COVID-19 pandemic, FHW experienced depression, anxiety, and inadequate social support. The marital status and age had a major impact on social support. Social support was inversely associated with depression and anxiety. Improving the mental health of FHW by strengthening social support is crucial. Future studies are needed to investigate how to improve the level of social support and mental health condition of FHW facing public health emergencies in the future.
Harm avoidance, daily stress, and problematic smartphone use in children and adolescents
Authors: Yoo So Young , Park Su Mi , Choi Chi-Hyun , Chung Sun Ju , Bhang Soo-Young , Kim Jae-Won , Kweon Yong-Sil , Choi Jung-Seok 
Published: September 2022

ObjectiveTemperament is close to susceptibility to stress and the increased level of stress may lead problematic smartphone use (PSU). In this study, the relationships between harm avoidance (HA) as a personality trait, daily traits, and PSU in children and adolescents were investigated.MethodsAt baseline, all participants (184 children and adolescents, mean age 13.15 years) completed questionnaires on PSU using the Smartphone Addiction Scale-Short Version (SAS-SV) and the Korean Smartphone Addiction Proneness Scale (SAPS). The Daily Hassles Questionnaire (DHQ) and Junior Temperament and Character Inventory (JTCI) were also administered to evaluate stress levels and personality traits. SAS-SV, SAPS, and DHQ were reassessed at 3 and 6 months.ResultsAmong JTCI temperament, HA displayed robust positive correlations with SAS-SV, SAPS, and DHQ at all time points. Mediation effects of daily stress on the relationship between HA and PSU were observed at baseline, 3, and 6 months.ConclusionThe findings suggest that managing stress may important in PSU children and adolescents with high HA.
Quarantine and demographic characteristics as predictors of perceived stress and stress responses during the third year of COVID-19 in China
Authors: Gao Qi , Xu Huijing , Shi Kaitian , Zhang Yi , Zhang Cheng , Jiang Qian , Wei Xiaoliang , Liu Taosheng 
Published: September 2022

BackgroundQuarantine as one of the most effective epidemic prevention measures, significantly increased people's stress levels. Ongoing monitoring of the stress status of people under quarantine during the pandemic is an important part of assessing the long-term impact of COVID-19 on mental health. This study aimed to gain a more comprehensive understanding of the stress status of people under quarantine, including perceived stress and stress responses, during the third year of the COVID-19 pandemic in China.MethodsAn anonymous online survey was conducted among 464 participants from 39 cities in China from March 31 to April 12, 2022. The survey included three questionnaires: a self-designed questionnaire collecting demographic information and quarantine characteristics, the Perceived Stress Scale (PSS-10) and the Stress Response Questionnaire (SRQ). The t-test or one-way ANOVA or the Welch F-test were used to examine the differences among demographic and quarantine variables of perceived stress and stress responses, then multiple linear regressions were performed to identify the predictors of perceived stress and stress responses.Results428 valid respondents were finally included. The average scores of perceived stress, total stress response, emotional response, physical response, and behavioral response were 14.70 ± 7.02, 50.24 ± 22.48, 20.35 ± 9.99, 15.23 ± 7.25, and 11.39 ± 5.27, respectively. The regression analysis showed that the degree of financial worries and days of continuous quarantine were the predictors of perceived stress. The degree of financial worries was a vital factor in predicting total stress response, emotional response, physical response and behavioral response, and in predicting emotional response, age was also a significant predictor.ConclusionThe stress status of individuals under quarantine was generally stable but still needs further attention during the third year of the COVID-19 pandemic. People who are young, have a high degree of financial worries and have been quarantined for a long time may be at a higher risk of perceived stress and stress responses. Relevant authorities should pay closer attention to the risk groups, and additional support and assistance might be required for those mostly worried about their financial situations under quarantine.
Health and nutrition emergency response among internally displaced persons at Ranch collective site, Chagni, Ethiopia: The role of emergency operation center, lessons from the field, and way forwards
Authors: Alemu Tefera , Bezabih Belay , Amsalu Abraham , Hassen Eyaya , Haile Mahteme , Abite Melkamu 
Published: September 2022

BackgroundIn October 2020, about 79,041 ethnically Amhara/Agew people had been internally displaced (IDPs) from Metekel zone of Benishangul-Gumuz region and lived in Ranch collective site, Chagni town, Ethiopia. Onsite PHEOC met the health and nutrition needs of the IDPs as per international humanitarian response standards.MethodsOn January 11/2021, the Amhara Public Health Institute (APHI) established an onsite Public Health Emergency Operation Center (PHEOC) at Ranch collective site. Health workers and vehicles were deployed. A temporary clinic having nine outlets was built. Drugs and medical supplies were mobilized from different sources. The overall response period lasted about 8 months, from December 2020 up to June 2021.ResultsA total of 33,410 IDPs had received free essential health services. Mental health and psychosocial support services had been given for 1,803 cases. Specialized medical services such as trachomatous trichiasis (30), cataract surgery (8) and sputum samples for mycobacterium tuberculosis (120) have been done. Moreover, 454 women received antenatal care services and 137 women gave birth at health facilities. About 837 children have got measles supplementary dose and 1,280 adults took a COVID-19 vaccination. A total of 1,448 children under five, 454 pregnant and 402 lactating women had been screened on monthly basis. Of which, severe and moderate malnutrition rate was 46 (3.2%) and 75 (5.2%), respectively. A total of 194 trench latrine seats, 74 shower rooms and 50 hand washing facilities had been constructed. There were no human feces present nor solid wastes accumulated around the shelters or settlements. Both active and passive surveillance activities were carried out throughout the camp life. We also conducted regularly Risk Communication and Community Engagement activities on priority health issues.ConclusionWe adequately met the health and nutrition needs of the IDPs as stated in the Sphere humanitarian handbook. We sought to have a strong Incident Management System and coordination platforms like PHEOC, a resilient health system, a training curriculum called Leading in Emergencies, and a multipurpose collective center with infrastructures, humanitarian response guidelines, training materials, and risk/vulnerability-based preparedness plan.
The acceptability and effectiveness of eHealth interventions to support assessment and decision-making for people with dementia living in care homes: A systematic review
Authors: Tunnard India , Gillam Juliet , Harvey Catherine , Davies Nathan , Vickerstaff Victoria , Ellis-Smith Clare , Evans Catherine J. 
Published: September 2022

IntroductionAs dementia progresses, care needs increase leading many to require 24-h care in care homes. eHealth interventions have the potential to improve care processes of assessment and decision-making for people with dementia. However, little is known on the acceptability and effectiveness in care homes.AimTo identify and explore the components, acceptability and effectiveness of eHealth interventions for people with dementia, families and staff to support assessment and decision-making in care homes.MethodsA mixed methods systematic review using narrative synthesis. Four databases were searched (Embase, PsycINFO, MEDLINE, and CINAHL) from 2000 to July 2021. Quality appraisal used validated assessment tools appropriate for the study design.ResultsTwenty-six studies met eligibility criteria. Study designs and interventions were heterogeneous. Overall quality was high to moderate. Interventions that promoted supportive, practical learning through integrated working and provided staff with language to communicate resident symptoms were favored by staff. We found evidence that indicated residents were willing to use video consultations; however, families preferred face-to-face consultations. Fifteen studies considered effectiveness. Use of eHealth interventions indicates an improvement in resident outcomes in appropriate prescribing and advance care planning. Staff knowledge, confidence, and wellbeing were also improved. Hospitalisations were reduced when a video consultation component was implemented.DiscussionCare home staff require support to meet the often multiple and changing care needs of residents with dementia. eHealth interventions can improve outcomes for staff and residents and facilitate integrated working with external professionals to support assessment and management of care. Further work is required to understand acceptability for residents and their families and effectiveness on family outcomes, particularly in non-Western cultures and low-middle income countries.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?RecordID=254967, identifier: CRD42021254967.
Can a reresection be avoided after initial en bloc resection for high-risk nonmuscle invasive bladder cancer? A systematic review and meta-analysis
Authors: Xu Jiangnan , Xu Zhenyu , Yin HuMin , Zang Jin 
Published: September 2022

BackgroundThis study aims to evaluate the effectiveness of en bloc resection for patients with nonmuscle invasive bladder cancer (NMIBC) and explore whether a reresection can be avoided after initial en bloc resection.Material and methodsWe conducted research in PubMed, EMBASE, Cochrane Library, and Web of Science up to October 12, 2021, to identify studies on the second resection after initial en bloc resection of bladder tumor (ERBT). R software and the double arcsine method were used for data conversion and combined calculation of the incidence rate.ResultsA total of 8 studies involving 414 participants were included. The rate of detrusor muscle in the ERBT specimens was 100% (95%CI: 100%–100%), the rate of tumor residual in reresection specimens was 3.2% (95%CI: 1.4%–5.5%), and the rate of tumor upstaging was 0.3% (95%CI: 0%–1.5%). Two articles compared the prognostic data of the reresection and non-reresection groups after the initial ERBT. We found no significant difference in the 1-year recurrence-free survival (RFS) rate (OR = 1.44, 95%CI: 0.67–3.09, P = 0.35) between the two groups nor in the rate of tumor recurrence (OR = 0.72, 95%CI: 0.44–1.18, P = 0.2) or progression (OR = 0.98, 95%CI: 0.33–2.89, P = 0.97) at the final follow-up.ConclusionsERBT can almost completely remove the detrusor muscle of the tumor bed with a very low postoperative tumor residue and upstaging rate. For high-risk NMIBC patients, an attempt to appropriately reduce the use of reresection after ERBT seems to be possible.
ACSL3 is a potential prognostic biomarker for immune infiltration in clear cell renal cell carcinoma
Authors: Zhang Chiyu , Hu Honglin , Huang Ruizhen , Huang Gaomin , Xi Xiaoqing 
Published: September 2022

ObjectiveLong-chain acyl-coenzyme A synthases (ACSLs) catalyze the activation of fatty acid and are often dysregulated in malignancies. The purpose of this research was to figure out the ACSL3's prognostic value and mechanism in clear cell renal cell carcinoma (ccRCC).MethodsThe expression of ACSL3 in ccRCC was investigated in this work using data from the GEO, TCGA, Oncomine and HPA databases. The expression differences of ACSL3 in the cell lines were further detected by qPCR and Western blot. GEPIA, MethSurv, cBioPortal, and the TIMER were used to perform survival and correlation analysis on ACSL3. GO and KEGG analyses were carried out in R using clusterProfiler and GOplot. Protein-protein interactions (PPI) are constructed from Strings website, and the results were visualized in Cytoscape software.ResultsThe expression level of ACSL3 was significantly reduced in ccRCC tissues, and its mRNA and protein expression were also significantly lower in both renal cancer cell lines. ACSL3 is significantly related to clinical stage, OS, DFS, DNA methylation, and immune-cell infiltration.ConclusionOur findings demonstrated that data mining was capable of eliciting information on ACSL3 levels and its role in genetic regulatory pathways in ccRCC.
The use of the pediatric physeal slide-traction plate in the treatment of neer–horwitz grade IV proximal humeral fractures in children: A case report and literature review
Authors: Qi Le , Jiang Yikun , Wang Yanbing , Peng Chuangang , Wu Dankai 
Published: September 2022

BackgroundProximal humeral fractures (PHFs) are rare in children. Currently, the recommended surgical methods for severely displaced PHFs are closed reduction and percutaneous fixation using K-wires or intramedullary nailing, which can't provide firm internal fixation, especially for older and high-weight children. This study aimed to introduce a novel surgical approach, pediatric physeal slide-traction plate fixation (PPSP), for Neer–Horwitz grade IV PHFs in children.Case summaryA 9-year-old boy presented with left shoulder pain and swelling due to a car accident. Physical examination revealed a positive shoulder deformity and local tenderness. On physical examination, we palpated bone friction without vascular and nerve damage. Based on imaging findings, we diagnosed Neer-Horwitz grade IV PHF. In view of the patient's condition, we performed PPSP after careful communication with the patient's parents. After 22 months of follow-up, the patient's left shoulder function was satisfactory, and there was no restriction of activities.ConclusionAccording to previous studies, PPSP is only used for femur fractures. To the best of our knowledge, this is the first in the treatment for PHFs. Given the satisfactory outcomes, it is a safe and effective method and may provide a reference to cure analogous patients in the future.
Analysis of risk factors of axial neck pain in posterior cervical single-door laminoplasty from the perspective of cervical sagittal plane
Authors: Zuo Kang Kang , Qin Wei , Miao Yu , Zhu Lei 
Published: September 2022

ObjectiveWe carried out this study to explore the possible relationship between the cervical sagittal parameters in radiological images and axial neck pain (ANP) for patients who had underwent posterior cervical single-door laminoplasty.Method141 patients were enrolled in the study from January 2018 to January 2021, among which 38 were enrolled into the ANP group and 103 were enrolled into the non-ANP group. C2–7 Cobb angle, C2–7 sagittal vertex axis (SVA), thoracic inlet angle, neck tilt, and T1 slope were measured using computed tomography. Spearman correlation tests were used to analyze the possible correlation between radiological parameters and ANP. Logistic regression was carried out to analyze the potential risk factor for the occurrence of ANP. Receiver operating characteristic (ROC) curve and area under the ROC curve were used to evaluate the significant result and the optimal diagnostic value.ResultsAs for radiographic parameters in the sagittal plane, the results suggested that only T1 slope and C2–7 SVA were statistically different between the ANP and non-ANP group (p = 0.001 and p = 0.047). Patients whose surgery involved the C2 spinous process demonstrated severe ANP symptoms than patients in the non-ANP group (p = 0.003). The Spearman correlation test showed that no statistical differences were found between visual analog scale (VAS) and radiological morphology parameters and only C2 involvement was found to correlate with postoperative VAS with respect to surgery. Logistic multivariate regression analysis demonstrated that only C2 involvement and T1 slope were significantly different when C2–7 SVA, T1 slope, C2 involvement together were included into consideration, with p values of 0.01 and 0.001.ConclusionAccording to our research, C2 involvement and greater T1 slope were independent risk factors of ANP for the patients who underwent laminoplasty of cervical spine.
An artificial neural network model based on standing lateral radiographs for predicting sitting pelvic tilt in healthy adults
Authors: Zhao Minwei , He Yuanbo , Li Shuai , Chen Huizhu , Li Weishi , Tian Hua 
Published: September 2022

BackgroundSpinopelvic motion, the cornerstone of the sagittal balance of the human body, is pivotal in patient-specific total hip arthroplasty.PurposeThis study aims to develop a novel model using back propagation neural network (BPNN) to predict pelvic changes when one sits down, based on standing lateral spinopelvic radiographs.MethodsYoung healthy volunteers were included in the study, 18 spinopelvic parameters were taken, such as pelvic incidence (PI) and so on. First, standing parameters correlated with sitting pelvic tilt (PT) and sacral slope (SS) were identified via Pearson correlation. Then, with these parameters as inputs and sitting PT and SS as outputs, the BPNN prediction network was established. Finally, the prediction results were evaluated by relative error (RE), prediction accuracy (PA), and normalized root mean squared error (NRMSE).ResultsThe study included 145 volunteers of 23.1 ± 2.3 years old (M:F = 51:94). Pearson analysis revealed sitting PT was correlated with six standing measurements and sitting SS with five. The best BPNN model achieved 78.48% and 77.54% accuracy in predicting PT and SS, respectively; As for PI, a constant for pelvic morphology, it was 95.99%.DiscussionIn this study, the BPNN model yielded desirable accuracy in predicting sitting spinopelvic parameters, which provides new insights and tools for characterizing spinopelvic changes throughout the motion cycle.
Development and validation of a nomogram to predict complications in patients undergoing simultaneous bilateral total knee arthroplasty: A retrospective study from two centers
Authors: Xu Kuishuai , Zhang Liang , Ren Zhongkai , Wang Tianrui , Zhang Yingze , Zhao Xia , Yu Tengbo 
Published: September 2022

PurposeComplications were significantly increased 30 days after Simultaneous bilateral total knee arthroplasty (SBTKA). In this study, an individualized nomogram was established and validated to predict the complications within 30 days after SBTKA.MethodsThe general data of 861 patients (training set) who received SBTKA in The Affiliated Hospital of Qingdao University between January 1, 2012 and March 31, 2017 were retrospectively analyzed. All patients were divided into complication group (n = 96) and non-complication group (n = 765) according to the incidence of complications within 30 years after SBTKA. Independent risk factors for postoperative SBTKA complications were identified and screened by binary logistic regression analyses, and then a nomogram prediction model was constructed using R software. The area under curve (AUC), calibration curve, and decision curve analysis (DCA) were selected to evaluate the line-chart. Meanwhile, 396 patients receiving SBTKA in the Third Hospital of Hebei Medical University who met the inclusion and exclusion criteria (test set) were selected to verify the nomogram.ResultsFive independent predictors were identified by binary logistic regression analyses and a nomogram was established. The AUC of this nomogram curve is 0.851 (95% CI: 0.819–0.883) and 0.818 (95% CI: 0.735–0.900) in the training and testing sets, respectively. In the training set and test set, calibration curves show that nomogram prediction results are in good agreement with actual observation results, and DCA shows that nomogram prediction results have good clinical application value.ConclusionOlder age, lower preoperative hemoglobin level, higher preoperative blood urea nitrogen (BUN) level, longer operation time, ASA grade ≥ III are independent predictors of SBTKA complications within 30 days after surgery. A nomogram containing these five predictors can accurately predict the risk of complications within 30 days after SBTKA.
Digital Reconstruction of Engineered Austenite: Revisiting Effects of Grain Size and Ausforming on Variant Selection of Martensite
Authors: Huang Cheng-Yao , Lu Shao-Lun , Yen Hung-Wei 
Published: September 2022

In this work, the variant selection of martensite in a stainless maraging steel was investigated by electron backscattering diffraction and a new protocol of parent phase reconstruction. The reconstruction protocol enables digital austenite reversion into prior austenite microstructure and provides information of variant selection from a large number of austenite grains. It was found that strong variant selection occurred when the prior austenite grains were significantly refined in annealing or severely deformed by ausforming. When the prior austenite grain size was finer than 20 μm, it was found that a pair of twinned variants dominated in one packet, which dominates the prior austenite grain. This finding is explained by the inefficient space left by the early transformed martensite in the dominant packet. In contrast, variants with the same Bain orientation occupied most of the space of the austenite when the strain of the austenite exceeded 50%. The accumulated microbands on the 1 1 1 plane acted as nucleation sites of specific variants of martensite. This work provides statistical results to revisit the variant selection of martensitic transformation with the assistance of computational crystallography.