bluuebunny/crossref_metadata_2025_split huggingface dataset:
Successful cerebral intravascular thrombectomy stops the heart stopping
Authors: Yong Vivien T. Y. , Caldwell James , Ershad Shakiya , Roxburgh Richard H. 
Published: August 2022

AbstractA 65‐year‐old man presented with an acute ischaemic stroke due to right posterior cerebral artery occlusion, complicated by episodes of sinus arrest in the absence of intrinsic cardiac disease. His neurological deficits and sinus node dysfunction resolved following mechanical thrombectomy. We believe this to be a novel case where thrombectomy resulted in successful treatment of cerebral ischaemia mediated cardiac autonomic dysfunction.
Approved gene therapies in Australia: coming to a store near you
Authors: Mallik Shreyashee , Bailey Charles G. , Rasko John E. J. 
Published: August 2022

AbstractGene therapy has been promising paradigm‐shifting advances in medical science for over two decades. Broadly, it is defined as a human therapy in which an existing defective gene function is added to, replaced, edited or disrupted to achieve a clinical benefit, up to and including a potential lifelong cure. Although originally set out to treat monogenic disorders, gene therapy has since been utilised to treat neoplasia, cardiovascular and neurodegenerative diseases, as well as infections. The realisation of this therapy has been dependent on the achievement of fundamental milestones in medicine, from determining the human genome sequence to identifying effective vehicles for the gene of interest, ultimately facilitating gene delivery in humans. In this review, six approved gene and cell therapies available in Australia are described. Their efficacy, adverse effects, limitations and eligibility are discussed, as well as an overview of cost and future directions.
Risk factors associated with 30‐day unplanned hospital readmission for patients with mental illness
Authors: Zhou Huaqiong , Ngune Irene , Albrecht Matthew A. , Della Phillip R. 
Published: August 2022

AbstractUnplanned hospital readmission rate is up to 43% in mental health settings, which is higher than in general health settings. Unplanned readmissions delay the recovery of patients with mental illness and add financial burden on families and healthcare services. There have been efforts to reduce readmissions with a particular interest in identifying patients at higher readmission risk after index admission; however, the results have been inconsistent. This systematic review synthesized risk factors associated with 30‐day unplanned hospital readmissions for patients with mental illness. Eleven electronic databases were searched from 2010 to 30 September 2021 using key terms of 'mental illness', 'readmission' and 'risk factors'. Sixteen studies met the selection criteria for this review. Data were synthesized using content analysis and presented in narrative and tabular form because the extracted risk factors could not be pooled statistically due to methodological heterogeneity of the included studies. Consistently cited readmission predictors were patients with lower educational background, unemployment, previous mental illness hospital admission and more than 7 days of the index hospitalization. Results revealed the complexity of identifying unplanned hospital readmission predictors for people with mental illness. Policymakers need to specify the expected standards that written discharge summary must reach general practitioners concurrently at discharge. Hospital clinicians should ensure that discharge summary summaries are distributed to general practitioners for effective ongoing patient care and management. Having an advanced mental health nurse for patients during their transition period needs to be explored to understand how this role could ensure referrals to the general practitioner are eventuated.
Impact of compassion satisfaction and compassion fatigue on satisfaction with life in Serbian and Polish nurses: A cross‐sectional study
Authors: Milutinović Dragana , Marcinowicz Ludmila , Jovanović Nina Brkić , Dragnić Nataša 
Published: August 2022

AbstractAims and objectivesTo evaluate demographic and occupational factors of professional life on life satisfaction among nurses in Serbia and Poland.BackgroundCompassion satisfaction and compassion fatigue, as aspects of a nurse's professional life, may affect their satisfaction with life in general. However, most studies on this topic have been conducted in Asian countries, and because there are differences in health care system performance across countries amid a global shortage of nurses, it is necessary to investigate professional quality of life in the European nursing context.MethodsThis multicenter, comparative, and correlational study was conducted on a sample of 669 hospital nurses in Serbia and Poland. The survey data were collected between November 2019 and February 2020 using the Demographic and Occupational Questionnaire (DOQ), Professional Quality‐of‐Life Scale (ProQOL‐5), and Satisfaction with Life Scale (SWLS). STROBE Statement guidelines for cross‐sectional studies were followed.ResultsMost nurses from both countries reported having moderate compassion satisfaction, moderate risk for compassion fatigue, and an average life satisfaction. The predictive factors of life satisfaction that most stand out include country of origin, financial situation, education, job satisfaction, and compassion fatigue.Discussion and conclusionQuality of professional life is significantly affected by shift duration, age, work experience, and job satisfaction. Negative aspects of professional life are significant predictors of life satisfaction.Implications for nursing policyThe findings of this study indicate a need for implementing flexible shift patterns and enhancing interventions that will improve job satisfaction and compassion satisfaction while reducing the risk of compassion fatigue.
Enhancing governance practice for better performance of credit union cooperatives in Thailand
Authors: Kumkit Tidarat , Gan Christopher , Anh Dao Le Trang , Hu Baiding 
Published: August 2022

AbstractCredit union cooperatives (CUCs) are member‐owned financial organisations that aim to improve the members’ living standards in Thailand. The success of Thailand CUCs is significantly associated with their good governance practices. This study provides an overview of Thailand CUCs’ governance practices and examines the impact of governance on the performance of Thailand CUCs. The study finds Thailand CUCs’ success varies in terms of financial and social performance. The results suggest that Thailand CUCs’ performance is affected by members’ participation, the board of directors, the management team, as well as the organisations’ age and size. This study extends the current limited knowledge on the governance‐performance nexus of Thailand CUCs in the literature, thus helping Thailand policymakers and practitioners boost both the financial and social performance of the CUCs in Thailand.
Imaging and plate counting to quantify the effect of an antimicrobial: A case study of a photo-activated chlorine dioxide treatment
Authors: Parker Albert E. , Miller Lindsey , Adams Jacob , Pettigrew Charles , Buckingham-Meyer Kelli , Summers Jennifer , Christen Andres , Goeres Darla 
Published: August 2022

Abstract

Aim
To assess removal versus kill efficacies of antimicrobial treatments against thick biofilms with statistical confidence.

Methods and results
A photo-activated chlorine dioxide treatment (Photo ClO2) was tested in two independent experiments against thick (&gt;100 μm) Pseudomonas aeruginosa biofilms. Kill efficacy was assessed by viable plate counts. Removal efficacy was assessed by 3D confocal scanning laser microscope imaging (CSLM). Biovolumes were calculated using an image analysis approach that models the penetration limitation of the laser into thick biofilms using Beer's Law. Error bars are provided that account for the spatial correlation of the biofilm's surface. The responsiveness of the biovolumes and plate counts to the increasing contact time of Photo ClO2 were quite different, with a massive 7 log reduction in viable cells (95% confidence interval [CI]: 6.2, 7.9) but a more moderate 73% reduction in biovolume (95% CI: [60%, 100%]). Results are leveraged to quantitatively assess candidate CSLM experimental designs of thick biofilms.

Conclusions
Photo ClO2 kills biofilm bacteria but only partially removes the biofilm from the surface. To maximize statistical confidence in assessing removal, imaging experiments should use fewer pixels in each z-slice, and more importantly, at least two independent experiments even if there is only a single field of view in each experiment.

Significance and impact of study
There is limited penetration depth when collecting 3D confocal images of thick biofilms. Removal can be assessed by optimally fitting Beer's Law to all of the intensities in a 3D image and by accounting for the spatial correlation of the biofilm's surface. For thick biofilms, other image analysis approaches are biased or do not provide error bars. We generate unbiased estimates of removal and assess candidate CSLM experimental designs of thick biofilms with different pixilations, numbers of fields of view and number of experiments using the included design tool.
Predictors of psychological resilience trajectories in patients with knee arthroplasty: A longitudinal study
Authors: Shan Yawei , Liu Xiaoyu , Chen Weijia , Chen Ru , Jin Lijuan , Sun Huimin , Lu Haiying 
Published: August 2022

AbstractAimsTo identify the different classes of total knee arthroplasty patients according to the heterogenous trajectories of psychological resilience and investigate the predictors for different patterns of resilience.DesignA prospective cohort study.MethodsA total of 210 patients with total knee arthroplasty from March to December 2021 were included. Baseline assessment (T0) data were collected before surgery and included demographic, biological (clinical characteristics), psychological (psychological resilience, self‐efficacy, psychological distress, hope, medical coping mode) and social (social support) factors. Resilience measurements were repeated at 3 days after surgery (T1), the date of discharge (T2), and 1 month (T3) and 3 months (T4) after discharge. Latent growth mixture modelling was employed to define different resilience trajectories. Predictors of class membership were identified using multinomial logistic regression.ResultsData from 198 patients were analysed. Three latent classes were identified with similar patterns in different intercepts, showing a significant decrease in resilience from admission (T0) to 3 days after surgery (T1) followed by an increase from T1 to T4. The three trajectories of psychological resilience were named the stable‐resilience class (65.66%), high‐resilience class (17.68%), and low‐resilience class (16.66%). Multinomial logistic regression showed that compared with the stable‐resilience class, the high‐resilience class was predicted by having a higher level of hope, having higher education, living in urban areas and having more children, while the low‐resilience class was predicted by having lower levels of self‐efficacy and hope, living in semirural areas, and having more children.ConclusionsThe three trajectories indicated that surgery was the major stressor influencing patients' psychological resilience and that patients in the low‐resilience class needed to be intervened.ImpactPredictors of patients in different classes provide evidence for the identification of vulnerable populations and lay a foundation for future research contributing to the development of targeted interventions for improving patients' psychological resilience.No patient or public contribution but the time points of investigation were decided based on our interviews with 12 total knee arthroplasty patients.
Cell delivery systems: Toward the next generation of cell therapies for type 1 diabetes
Authors: Dang Hoang Phuc , Chen Hui , Dargaville Tim R. , Tuch Bernard E. 
Published: August 2022

AbstractImmunoprotection and oxygen supply are vital in implementing a cell therapy for type 1 diabetes (T1D). Without these features, the transplanted islet cell clusters will be rejected by the host immune system, and necrosis will occur due to hypoxia. The use of anti‐rejection drugs can help protect the transplanted cells from the immune system; yet, they also may have severe side effects. Cell delivery systems (CDS) have been developed for islet transplantation to avoid using immunosuppressants. CDS provide physical barriers to reduce the immune response and chemical coatings to reduce host fibrotic reaction. In some CDS, there is architecture to support vascularization, which enhances oxygen exchange. In this review, we discuss the current clinical and preclinical studies using CDS without immunosuppression as a cell therapy for T1D. We find that though CDS have been demonstrated for their ability to support immunoisolation of the grafted cells, their functionality has not been fully optimized. Current advanced methods in clinical trials demonstrate the systems are partly functional, physically complicated to implement or inefficient. However, modifications are being made to overcome these issues.
Giving up on the objective of providing goal‐concordant care: Advance care planning for improving caregiver outcomes
Authors: Fried Terri R. 
Published: August 2022

AbstractThe merits and effectiveness of advance care planning (ACP) continue to be debated a full 30 years after the passage of the Patient Self‐Determination Act. This act gave patients the right to create advance directives, with the objective of ensuring that the care they received at the end of life was consistent with their preferences and goals. ACP has definitively moved beyond the completion of advance directives to encompass the identification of a healthcare agent and the facilitation of communication among patients, surrogates, and clinicians. Nonetheless, the provision of goal‐concordant care remains a primary objective for ACP. This article argues that this cannot and should not be the objective for ACP. Patients' goals change, and the provision of goal‐concordant care is sometimes incompatible with other critical determinants of appropriate care. Instead, ACP should focus on the objective of improving caregiver outcomes. Surrogate decision‐making by caregivers is associated with an elevated risk of post‐traumatic stress disorder and other adverse outcomes, and these outcomes can be improved with ACP. ACP focused on caregivers involves helping caregivers to understand how they can help to shape the final chapter in a patient's life story, preventing caregivers from making promises they cannot keep, and preparing them to use all relevant information at the time decisions need to be made.
Assessment of serum chemerin levels in acanthosis nigricans: A case–control study
Authors: Afify Ahmed Abdelfattah , Fathy Ghada , Elzawahry Menna , Taha Sara Ibrahim 
Published: August 2022

AbstractBackgroundAcanthosis nigricans (AN) is an asymptomatic skin condition linked to several underlying systemic conditions. Chemerin is an adipokine that increases during inflammatory disorders such as metabolic syndrome (MetS).AimsThis case–control study investigates the link between AN and the underlying MetS and serum levels of chemerin in individuals with obesity.Patients/MethodsTwenty‐five adults with AN and obesity (body mass index [BMI] > 30 kg/m2), 25 adults with obesity but no AN, and 25 healthy controls (BMI < 30 kg/m2) had their lipid profiles and serum chemerin concentrations examined.ResultsThe neck (80.0%) and axilla (68.0%) were the most common sites of AN. In participants with obesity, either alone or with AN, serum chemerin concentrations were significantly higher than in the control group (p < 0.001). Participants with obesity and AN had significantly higher levels of cholesterol, triglycerides (TG), low‐density lipoprotein cholesterol (LDL‐c), and serum chemerin levels (p < 0.001), and significantly lower high‐density lipoprotein cholesterol (HDL‐c) levels (p < 0.001) when compared to participants with obesity alone. All participants with obesity and AN (100%) and 88% of those with obesity alone had MetS. Logistic regression revealed that systolic blood pressure >130 mmHg, diastolic blood pressure >85 mmHg, waist circumference >90 cm, TG >150 mg/dl, HDL‐c <45 mg/dl, fasting blood glucose >100 mg/dl, and serum chemerin >300 ng/ml were significant (p < 0.05) risk factors for AN.ConclusionsAcanthosis nigricans is a non‐invasive and reliable sign of the underlying MetS and increased serum chemerin levels among individuals with obesity.
Panthers and Lions
Authors: Feller Yaniv 
Published: August 2022

ABSTRACTShaul Magid's Meir Kahane: The Public Life and Political Thought of an American Jewish Radical (2021) stresses the American character of Kahane's thought. This review analyzes this claim in two ways. First, it offers a transnational perspective on Kahane's philosophy. Second, it examines Magid's concept of neo‐Kahanism in light of Kahane's legacy in Israel.
Lower cold tolerance of tropical Porites lutea is possibly detrimental to its migration to relatively high latitude refuges in the South China Sea
Authors: Huang Wen , Yang Enguang , Yu Kefu , Meng Linqing , Wang Yonggang , Liang Jiayuan , Huang Xueyong , Wang Guanghua 
Published: August 2022

AbstractAs high temperature stress due to climate change threatens tropical corals, cooler areas at relatively high latitudes may be potential refuges. Tolerance to low temperatures is critical in determining whether corals can successfully migrate to higher latitudes. However, the physiological and molecular adaptations that protect corals from low temperature stress are unclear. In this study, scleractinian Porites lutea samples from the tropical Xisha Islands (XS) and subtropical Daya Bay (DY) in the South China Sea were subjected to a reduction in ambient temperature from 26 to 12°C. Differences in physiological changes and gene expression were analysed. P. lutea from both XS and DY exhibited physiological bleaching under low temperature stress, and the Symbiodiniaceae density, Fv/Fm, and chlorophyll‐α content were significantly reduced. Symbiosome antioxidative stress and metabolic enzyme activity first increased and then decreased. RNA‐seq analysis showed that the host responded to low temperature stress by activating immune, apoptotic, and autophagic pathways and reducing metabolic levels. Nevertheless, Symbiodiniaceae lacked the physiological regulatory capacity to adapt to low temperatures. The lower cold tolerance of XS tropical P. lutea may attribute to lower oxidative stress resistance, lower photosynthetic capacity, worse energy supply, and higher susceptibility to bacterial and viral infections and diseases in XS corals. The difference in cold tolerance may result from genetic differences between the geographic populations and is possibly detrimental to the migration of tropical coral to relatively high latitude refuges. This study provides a theoretical basis for anthropogenically assisted coral migration as a response to global change.
Rhythmic serious games as an inclusive tool for music‐based interventions
Authors: Dalla Bella Simone 
Published: August 2022

AbstractTechnologies, such as mobile devices or sets of connected sensors, provide new and engaging opportunities to devise music‐based interventions. Among the different technological options, serious games offer a valuable alternative. Serious games can engage multisensory processes, creating a rich, rewarding, and motivating rehabilitation setting. Moreover, they can be targeted to specific musical features, such as pitch production or synchronization to a beat. Because serious games are typically low cost and enjoy wide access, they are inclusive tools perfectly suited for remote at‐home interventions using music in various patient populations and environments. The focus of this article is in particular on the use of rhythmic serious games for training auditory–motor synchronization. After reviewing the existing rhythmic games, initial evidence from a recent proof‐of‐concept study in Parkinson's disease is provided. It is shown that rhythmic video games using finger tapping can be used with success as an at‐home protocol, and bring about beneficial effects on motor performance in patients. The use and benefits of rhythmic serious games can extend beyond the rehabilitation of patients with movement disorders, such as to neurodevelopmental disorders, including dyslexia and autism spectrum disorder.
Pollination syndrome accurately predicts pollination by tangle‐veined flies (Nemestrinidae: Prosoeca s.s.) across multiple plant families
Authors: Pauw A. 
Published: August 2022

ABSTRACT
The idea that a syndrome of floral traits predicts pollination by a particular functional group of pollinators remains simultaneously controversial and widely used because it allows plants to be rapidly assigned to pollinators. To test the idea requires demonstrating that there is an association between floral traits and pollinator type.
I conducted such a test in the Cape Floristic Region of South Africa, by studying the pollination of eight plant species from six families that flower in spring and have scentless, actinomorphic, upwards‐facing flowers, with orbicular petals all held in the same plane. The petals are brilliant‐white with red‐purple nectar guides. The tubes are short and hold small volumes of concentrated nectar, except in the rewardless Disa fasciata (Orchidaceae). Pollinators were photographed and captured, pollen loads were analysed and pollination networks were constructed.
Consistent with the pollination syndrome hypothesis, the species with the defined syndrome shared a small group of pollinators. The most frequent pollinators belonged to a clade of four tangle‐veined fly species with relatively short proboscises (Nemestrinidae: Prosoeca s.s.), while functionally similar Bombyliidae and Tabanidae played minor roles. Among the four Prosoeca species, only Prosoeca westermanni has been described, a result that highlights our ignorance about pollinators.
The demonstration of an association between the syndrome of traits and pollination by this group of flies explains the repeated evolution of the syndrome across multiple plant families, and allows prediction of pollinators in additional species. More generally, the result validates the idea that the traits of organisms determine their ecology.
Populus × canescens root suberization in reaction to osmotic and salt stress is limited to the developing younger root tip region
Authors: Grünhofer Paul , Stöcker Tyll , Guo Yayu , Li Ruili , Lin Jinxing , Ranathunge Kosala , Schoof Heiko , Schreiber Lukas 
Published: August 2022

AbstractPopulus is a valuable and fast‐growing tree species commonly cultivated for economic and scientific purposes. But most of the poplar species are sensitive to drought and salt stress. Thus, we compared the physiological effects of osmotic stress (PEG8000) and salt treatment (NaCl) on poplar roots to identify potential strategies for future breeding or genetic engineering approaches. We investigated root anatomy using epifluorescence microscopy, changes in root suberin composition and amount using gas chromatography, transcriptional reprogramming using RNA sequencing, and modifications of root transport physiology using a pressure chamber. Poplar roots reacted to the imposed stress conditions, especially in the developing younger root tip region, with remarkable differences between both types of stress. Overall, the increase in suberin content was surprisingly small, but the expression of key suberin biosynthesis genes was strongly induced. Significant reductions of the radial water transport in roots were only observed for the osmotic and not the hydrostatic hydraulic conductivity. Our data indicate that the genetic enhancement of root suberization processes in poplar might be a promising target to convey increased tolerance, especially against toxic sodium chloride.