bluuebunny/crossref_metadata_2025_split huggingface dataset:
Combination of plastic surgery of the pyeloureteral junction with kidney transposition and nephropexy in hydronephrosis of a dystopic kidney
Authors: Laletin D. I. , Firsov M. A. , Bodyagin V. Y. , Bezrukov E. A. , Simonov P. A. 
Published: June 2022

Introduction. Obstruction of the pyeloureteral junction is the most common anomaly of the upper urinary tract. Irrespective of the causes, narrowing of the ureteropelvic junction leads to abnormal urine outflux, increased intrarenal pressure, gradual sclerosis of renal parenchyma, loss of kidney function. In some cases, obstruction of the ureteropelvic junction can be accompanied by dystopic kidney, nephroptosis, abnormal location of the main and accessory renal vessels which requires correction of the standard surgical treatment.The study objective is to evaluate the effectiveness of combination of laparoscopic pyeloplasty with kidney transposition and nephropexy in obstruction of the pyeloureteral junction of a dystopic kidney.Materials and methods. Medical records of 8 patients who underwent surgery in the Kracnoyarsk Regional Clinical Hospital between 2017 and 2021 were analyzed. Obstruction of the pyeloureteral junction was confirmed clinically by ultrasound of the kidneys, excretory retrograde pyelography, contrast-enhanced spiral computed tomography.Results. In all of the 8 patients, lumbar dystopia of the affected kidney was diagnosed, in 25 % pathology was accompanied by nephroptosis, in 50 % of cases by abnormal location of the main and accessory renal vessels. All patients underwent laparoscopic plastic surgery of the pyeloureteral junction per Anderson–Hynes with antegrade ureter stenting, kidney transposition, nephropexy. Mean operative time was 190 ± 39 min, no intraoperative blood loss was observed. Ureteral catheter was removed at day (6.3 ± 2.2). Hospital length of stay was 9.3 ± 3.7 days. In 1 patient, postoperative period was complicated by suture breakage in the posterior wall of the pyeloureteral anastomosis which required repeat laparoscopy to correct suture defect. Time of ureteral stent implantation was 34.6 ± 8.5 days. Control examination showed full remission of pain syndrome. Excretory urography showed full outflow of the contrast agent after examination with furosemide in 100 % of cases.Conclusion. Combination of laparoscopic plastic surgery of the pyeloureteral segment with kidney transposition and nephropexy is an effective minimally invasive operation for treatment of ureteropelvic junction stricture of a dystopic kidney.
Diagnostic precision of C-reactive protein to albumin ratio for coagulopathy in patients with COVID-19
Authors: KARATAŞ KILIÇCIOĞLU Gizem , KAYA Tezcan , İŞSEVER Kubilay , GÜÇLÜ Ertuğrul , KARABAY Oğuz 
Published: June 2022

Purpose: This study aims to assess the diagnostic utility of C-reactive protein (CRP) to albumin ratio (CAR) for predicting elevated D-dimer levels in COVID-19.
Materials and Methods: This retrospective cohort study collected data from 145 hospitalized patients with confirmed COVID-19 in a university hospital. Patients were divided into two groups based on their D-dimer levels, as elevated D‐dimer levels and normal D-dimer levels. Demographic data, comorbidities, clinical symptoms, CAR, and laboratory results were obtained from the patients’ medical records and compared between the groups.
Results: The mean age of patients was 52.9±17.9 years, and 76 of them were male. The median of CAR was significantly higher in those with higher D-dimer (134.1 vs. 20.7). CRP, procalcitonin, leukocyte, neutrophil, lactate dehydrogenase, ferritin, and fibrinogen were higher in patients with elevated D-dimer levels. There was a highly significant positive correlation between CAR and D-Dimer. Logistic regression analysis revealed that CAR was a significant determinant for elevated D‐dimer levels . The area under the ROC curve (AUC) was 0.741 for CAR. The verified cut-off value of CAR for predicting elevated D‐dimer levels in patients with COVID-19 was 81.8, with a sensitivity of 58% and a specificity of 70%.
Conclusion: Our study revealed that CAR was significantly correlated with D-dimer and can be used to predict elevated D‐dimer levels in patients with COVID-19.
Cerrahi olarak tedavi edilen yetişkin ayak bileği kırıklarında üç farklı hasta bazlı değerlendirme ölçek sonuçlarının karşılaştırılması
Authors: FAKIOĞLU Remzi Can , GENCER Batuhan , UTKAN Ali 
Published: June 2022

Amaç: Bu çalışmda ayak bileği kırıklarının ameliyat sonrası klinik ve radyolojik sonuçlarının üç farklı hasta bazlı değerlendirme ölçeği kullanılarak değerlendirilmesi ve ölçeklerinin sonuçlarının ve birbirleri ile uyumlarının karşılaştırılması amaçlanmıştır.
Gereç ve Yöntem: Yaşları 18 ile 77 arasında değişen toplam 77 hasta prospektif olarak takip edildi. Tüm hastaların yaş, cinsiyet, kırık taraf, travma mekanizmaları, kırık tipleri, ameliyat sonrası atel uygulanma süreleri, tam yük vermeye başlama zamanları ve komplikasyonları kaydedildi. Hastaların 1. yıl kontrollerinde tüm hastalar, AOFAS, Ayak Bileği-Arka Ayak Değerlendirme Ölçeği, Weber Skorlaması ve Freiburg Skalası protokollerine göre incelendi.
Bulgular: AOFAS Değerlendirme Ölçeğine göre 57 hastada (%74) iyi ve 20 hastada (%26) kötü sonuç; Weber Skorlamasında 51 hastada (%66,2) mükemmel, 12 hastada (%15,6) iyi ve 14 hastada (%18,2) kötü sonuç ve Freiburg Skalasında 50 hastada (%64,9) mükemmel, 12 hastada (%15,6) iyi ve 15 hastada (%19,5) kötü sonuç elde edilmiştir. AOFAS-Weber, Ölçek sonuçları birbirleri ile uyumlu bulunmuştur. Komplikasyon gelişimi ile AOFAS Değerlendirme Ölçeği ve Weber Skorlaması arasında ve ileri yaş ile Weber Skorlaması arasında anlamlı ilişki saptanmıştır.
Sonuç: AOFAS Ölçeği, Weber Skorlaması ve Freiburg Skalalarının sonuçları birbirleri ile uyumlu olup, yetişkin ayak bileği kırıklarının cerrahi tedavisi sonrası değerlendirilmesinde güvenle kullanılabilir. Komplikasyon gelişimi ve ileri yaş, ayak bileği kırıklarında kötü klinik sonuç ile ilişkilendirilebilir.
A rare case of Mönckeberg medial calcific sclerosis simulating giant cell arteritis
Authors: OKYAR Burak , TORUN Bekir , ALBAYRAK Fatih , KOÇARSLAN Sezen , YILDIZ Fatih , YILDIRIM ÇETİN Gözde 
Published: June 2022

Background: Mönckeberg Medial Calcific Sclerosis (MMCS) is a rare condition that can mimic giant cell arteritis (GCA). It may be misinterpreted as giant cell arteritis by the clinician and cause unnecessary treatments. Therefore, it is a disease that should be differentiated from giant cell arteritis with its clinical, radiological, and pathological findings.
Case Presentation: A 56-year-old female patient was admitted to our clinic with sudden unilateral vision loss on the right, pain in the right temporal artery trace, scalp sensitivity in the section corresponding to that area, difficulty chewing, and temporal artery sensitivity. He had a history of hemodialysis for 13 years due to hypertension, osteoporosis, a history of renal stones, and end-stage renal failure. In routine blood tests, White Blood Cell: 7.86X109/L, Hemoglobulin: 10.9 g/dL, C-reactive protein: 3.03 mg/L, Erythrocyte sedimentation rate: 53 mm/hour came. As a result of temporal artery biopsy performed for GCA, absence of giant cells, absence of epithelioid histiocytes, absence of pathological findings in the internal elastic lamina, diffuse calcification in the tunica media, and sclerosis was diagnosed as MMCS.
Conclusions: In the literature, 4 case reports resemble giant cell arteritis and are diagnosed as MMCS. This case report is a rare case report showing that MMCS can completely mimic GCA findings.
Clinical use of long-acting antipsychotics for the treatment of bipolar disorder type I patients
Authors: UYAR Betül , ATLI Abdullah , GÜL BİLEN Derya 
Published: June 2022

Purpose: This study aims to determine the usage frequency of long-acting injectable antipsychotics among bipolar disorder type 1 patients who presented to the Dicle University Faculty of Medicine Psychiatry and Mental Health outpatient clinic, the clinical characteristics of these patients, and the preferences of clinicians about these agents.
Materials and Methods: Our study included 111 patients older than 18 years old with bipolar disorder. The ’data of the patients were retrospectively obtained from electronic data records. The data were recorded in the data collection form prepared by the researchers with the support of the literature.
Results: The rate of the patients who used long-acting injectable antipsychotics was 21.6%. Among the patients who used long-acting injectable antipsychotics, the rate of those who used second-generation long-acting injectable antipsychotics was 58.3%, and the most frequently preferred agent was paliperidone palmitate. The patients who were using long-acting injectable antipsychotics had significantly higher rates of not working and numbers of hospitalizations.
Conclusion: Our results showed that long-acting injectable antipsychotics are preferred by clinicians in our outpatient clinic in the later stages of bipolar disorders and for patients with poor drug compliance, poor functionality, and more hospitalizations. Starting long-acting injectable antipsychotics in the early stages of bipolar disorders, even following the first attack, may increase treatment compliance, reduce the duration of hospitalization, and contribute to the functionality of patients.
Effect of Melissa officinalis L. on human breast cancer cell line via apoptosis and autophagy
Authors: BİTGEN Nazmiye , BARAN Münevver , ÖNDER Gözde Özge , ALİŞAN SUNA Pınar , GÜRBÜZ Perihan , YAY Arzu 
Published: June 2022

Purpose: The aim of this research is to see how Melissa officinalis L. affects the death pathways of MCF-7 breast cancer cells in vitro.
Materials and Methods: In order to determine the cytotoxic activity and IC50 value of the 70% methanolic extract prepared from the aerial parts of Melissa officinalis, on the MCF-7 breast cancer cell line; the extract was applied at different concentrations and times and MTT analysis was performed. Apoptotic effects of Melissa officinalis on breast cancer cells at the determined IC50 dose were revealed by TUNEL method, and autophagic effects were revealed using Beclin-1 and LC3 immunofluorescence staining method.
Results: When the effects of Melissa officinalis on MCF-7 breast cancer cells were evaluated, it was observed that the cell viability of the MCF-7 breast cancer cell line was decreased in a dose- and time-dependent manner. In addition, it was observed that it induced apoptosis and increased the immunoreactivity of autophagy markers Beclin-1 and LC3.
Conclusion: Findings from the study showed that Melissa officinalis has a cytotoxic effect on MCF-7 breast cancer cells through both apoptosis and autophagy cell death pathways. These data will lead to further in vitro studies necessary to elucidate the antitumor mechanism of action.
Semptomatik veya asemptomatik primer hiperparatiroidisi olan hastaların biyokimyasal parametreleri ile CDKN1B mutasyon analizi tayini
Authors: AKKUŞ Gamze , ŞENGÖZ COŞKUN Nur Sinem , KARAGÜN Baris , TETİKER Bekir Tamer 
Published: June 2022

Amaç: Bu çalışmada semptomatik ve asemptomatik primer hiperparatiroidi (PHPT) olgularını karşılaştırmayı amaçladık, beraberinde sporadik saptanan paratiroid adenomlarında etyopatogenezde CDKN1B mutasyonu varlılığını saptamaya çalıştık.
Gereç ve Yöntem: Çalışmamıza kliniğimize başvuran 80 PHPT (66 K ve 14 E, ortalama yaş 50.8 ± 12.01 yıl) tanısı almış hasta dahil edilmiştir. Hastaların yaş, cinsiyet, biyokimyasal parametreleri, görüntüleme yöntemleri (nükleer sintigrafi, ultrasonografi, kemik dansitometre ölçümü) kayıt edilmiştir. CDKN1B gen sekanslaması için GeneMATRIX Quick Blood DNA Purification kiti kullanılarak DNA izole edilmiştir. CDKN1BF (rs786201010, c.-456_-453delCCTT) (CAGGTTTGTTGGCAGCAGTA) ve CDKN1BR (rs786201010, c.-456_-453delCCTT) (GGAGCCAAAAGACACAGACC) primerleri seçilerek mutasyon analizi yapılmıştır.
Bulgular: Çalışma sonucunda 22 hasta asemptomatik PHPT olarak tanımlanmış olup semptomatik PHPT (n=68) serum kalsiyum parametreleri ve 24 saatlik idrar Ca+ atılımı daha yüksek olarak saptanmıştır. Serum Parathormon (PTH) değerleri her iki grupta da benzerdi. Her iki grupta da CDKN1B mutasyonu açısından patolojik bir bulgu saptanmamıştır.
Sonuç: Parathormon seviyeleri semptomatik veya asemptomatik PHPT olgularında belirleyici bir parametre olmamakla birlikte semptomatik PHPT da serum kalsiyum değerleri ve 24 saatlik idrar Ca+ atılımı daha belirgindir.
Pengaruh Metode Bermain dan Komando Terhadap Hasil Belajar Keterampilan Passing Bawah Bola Voli Gandu Level II
Authors: Kristian Peter , Asim Asim 
Published: June 2022

Abstract: Physical education learning through the level II gandu volleyball game with play and command learning methods is an effort to make it easier for students and so that students are more interested in taking down passing lessons. The purpose of this research is to see the difference in the effect of the playing method with the commando method on the learning outcomes of low-passing skills in double-level volleyball in SMPN 1 Ijen students. Researchers use quasi-experimental method"The Two Group Pretest-Posttest Design" both groups were selected randomly. Hypothesis testing in this study uses one way ANOVA analysis. The results of this study for the play learning method group obtained an average pretest score of 18.07 and a posttest score of 48.13, and the command learning method group obtained an average pretest score of 18.53 and a posttest score of 69.53. It can be concluded that the learning of passing under the command method group got a better average score than the playing method group in the learning process of level II double volleyball for the students of SMPN 1 Ijen.
Abstrak: Pembelajaran pendidikan jasmani melalui permainan bolavoli gandu level II dengan metode pembelajaran bermain dan komando merupakan upaya untuk memudahkan siswa dan supaya siswa lebih tertarik untuk mengikuti pembelajaran passing bawah. Adapun penelitian ini untuk melihat perbedaan pengaruh metode bermain dengan metode komando terhadap hasil belajar keterampilan passing bawah bolavoli gandu level II pada siswa SMPN 1 Ijen. Peneliti memakai metode eksperimen semu “The Two Group Pretest-Posttest Design” kedua kelompok dipilih secara acak. Uji hipotesis dalam penelitian ini menggunakan analisis one way anova. Hasil dari penelitian ini untuk kelompok metode pembelajaran bermain diperoleh rata-rata skor pretest 18,07 dan skor posttest 48,13, serta kelompok metode pembelajaran komando diperoleh rata-rata skor pretest 18,53 dan skor posttest 69,53. Dapat disimpulkan pembelajaran passing bawah kelompok metode komando mendapat skor rata-rata lebih baik dibandingkan kelompok metode bermain dalam proses pembelajaran bolavoli gandu level II pada siswa SMPN 1 Ijen.
Survei Kondisi Fisik Peserta Ekstrakurikuler Sepakbola SMPN 2 Turen
Authors: Pratama Afrido Dias , Hariyanto Eko 
Published: June 2022

Abstract: Football is a sport that requires excellent stamina, therefore every player is required to have good physical condition. Likewise in football extracurricular activities at SMPN 2 Turen, poor physical abilities of players will also affect the techniques and tactics of football games. The purpose of this study was to determine the physical condition of the soccer extracurricular participants at SMPN 2 Turen. This research includes descriptive research with survey methods and data collection techniques using tests and measurements. From the four elements of physical condition that have been studied, it can be concluded that there are two elements that are in the "Enough" category, namely agility and speed, while the explosive power element is in the "Good" category and the endurance element is in the "Very Poor" category. So the results of the overall physical condition of the soccer extracurricular participants at SMPN 2 Turen show the "Enough" category.
Abstrak: Sepakbola merupakan olahraga yang membutuhkan stamina yang prima. Demikian juga pada kegiatan ekstrakurikuler sepakbola SMPN 2 Turen, kemampuan fisik yang buruk pada pemain akan berpengaruh juga dalam melakukan teknik dan taktik permainan sepakbola. Tujuan dari penelitian ini yaitu mengetahui kemampuan kondisi fisik peserta ekstrakurikuler sepakbola SMPN 2 Turen. Penelitian ini termasuk penelitian deskriptif dengan metode survei dan teknik pengumpulan data menggunakan tes dan pengukuran. Dari empat unsur kondisi fisik yang sudah diteliti dapat disimpulkan bahwa terdapat dua unsur yang berada pada kategori “Cukup” yaitu kelincahan dan kecepatan, sedangkan unsur daya ledak berada pada kategori “Baik” dan unsur daya tahan masuk dalam kategori “Sangat Kurang”. Jadi hasil keseluruhan kondisi fisik peserta ekstrakurikuler sepakbola SMPN 2 Turen menunjukkan kategori “Cukup”.
Survei Pertumbuhan Dan Perkembangan Motorik Kasar Pada Kelas Rendah Usia 7-9 Tahun di SD Se-Gugus 01 Kecamatan Lowokwaru Kota Malang
Authors: Siddiq Imam Ardian , Wiguno Lokananta Teguh Hari 
Published: June 2022

Abstract: The purpose of the study was to determine the growth and gross motor development of children aged 7 to 9 years in elementary school in cluster 01, Lowokwaru District, Malang City. The type of this research is descriptive quantitative. Using the anthropometric measurement method and the TGMD-2 test for students aged 7 to 9 elementary schools in cluster 01, Lowokwaru District, Malang City, there were average results for each age, while the test for gross motor skills of students aged 7 to 9 years obtained similar results very good.
Abstrak: Tujuan penelitian untuk mengetahui pertumbuhan dan perkembangan motorik kasar anak usia 7 sampai 9 tahun SD se-gugus 01 Kecamatan Lowokwaru Kota Malang. Jenis dari penelitian ini yaitu deskriptif kuantitatif. Menggunakan metode pengukuran antropometri dan tes TGMD-2 untuk siswa usia 7 sampai 9 SD se-gugus 01 Kecamatan Lowokwaru Kota Malang terdapat hasil rata-rata pada masing-masing usia, sedangkan tes untuk motorik kasar peserta didik usia 7 sampai 9 tahun memperoleh hasil yang sangat baik.
Kemampuan Fisik Atlet PPLPD Cabang Olahraga Gulat
Authors: Ayuningtias Mutiara , Nurrochmah Siti 
Published: June 2022

Abstract: The purpose of this research is to study and obtain information about physical abilities including the level of ability of the arms, shoulders, legs, explosive power of the arms and legs, and flexibility of the body muscles. The study used an observational method approach and the data were analyzed using descriptive statistics in the form of central tendency. The results of the data analysis showed that the arm muscle strength (50 percent) was dominant in the poor criteria, the right shoulder muscle strength (60 percent) left (36.66 percent) was dominant in the poor criteria, the leg muscle strength (56.66 percent) was dominant on the poor criteria, The explosive power of the arms (36.66 percent) is sufficiently dominant, the explosive power of the limbs (43.33 percent) is sufficiently dominant, and the flexibility of the muscles of the body (36.66 percent) is dominant in sufficient criteria.
Abstrak: Tujuan penelitian ini untuk mengkaji dan mendapatkan informasi mengenai kemampuan fisik yang meliputi tingkat kemampuan kekuatan otot lengan, bahu, tungkai, daya ledak otot lengan dan tungkai, dan kelentukan otot tubuh. Penelitian menggunakan pendekatan metode observasi dan data dianalisis menggunakan statistika deskriptif bentuk tendensi sentral. Hasil analisis data diperoleh kekuatan otot lengan (50 persen) dominan pada kriteria kurang, kekuatan otot bahu kanan (60 persen) kiri (36,66 persen) dominan pada kriteria kurang, kekuatan otot tungkai (56,66 persen) dominan pada kriteria kurang, daya ledak lengan (36,66 persen) dominan cukup, daya ledak tungkai (43,33 persen) dominan cukup, dan kelentukan otot tubuh (36,66 persen) dominan pada kriteria cukup.
Status Gizi Siswa Kelas 4-6 SDN-2 Tonatan diKecamatan Ponorogo Kabupaten Ponorogo di Era New Normal
Authors: Reynaldi Rivals , Nurrochmah Siti 
Published: June 2022

Abstract: The purpose of this study is to assess and determine the nutritional status of school-age children in grades 4-6 SDN 2 Tonatan in Ponorogo District, Ponorogo Regency in the new normal era. The design used is a survey and the approach used is an observation method in the form of measuring height and weighing. The population is students of SDN grades 4, 5, and 6 of SDN 2 Tonatan in Ponorogo District, Ponorogo Regency for the 2019/ 2020 academic year. The results of the study obtained data on students in grades 4-6 at SDN 2 Tonatan in Ponorogo District from the results of data analysis on the national standard nutritional status, in the male group of SDN 2 Tonatan the average was light fat criteria (GR), and in the female group of SDN 2 Tonatan On average, the criteria for being underweight (KB) are on average and the combined male and female students are in the criteria for being underweight (KB). The conclusion of the research on nutritional status shows that the results tend to be more classified for men with heavy weight and light weight for women.
Abstrak: Tujuan untuk mengetahui dan mengkaji status gizi anak usia sekolah siswa kelas 4-6 SDN 2 Tonatan di Kecamatan Ponorogo Kabupaten Ponorogo di era new normal. Rancangan yang digunakan berupa survei dan penedekatan yang digunakan berupa metode observasi berupa pengukuran tinggi badan dan penimbangan berat. Populasi adalah Siswa SDN kelas 4, 5, dan 6 SDN 2 Tonatan di Kecamatan Ponorogo Kabupaten Ponorogo tahun ajaran 2019/2020. Hasil penelitian diperoleh data pada siswa kelas 4-6 di SDN 2 Tonatan di Kecamatan Ponorogo hasil analisis data status gizi stadar Nasional, pada kelompok putra SDN 2 Tonatan rata-rata berada kriteria gemuk ringan (GR), dan pada kelompok siswa putri SDN 2 Tonatan rata-rata berada kriteria kurus berat (KB) dan pada gabungan siswa putra dan putri berada pada kriteria kurus berat (KB). Simpulan hasil penelitian status gizi menunjukkan hasil cenderung banyak yang tergolong untuk putra berat badan kurus berat dan putri berat kurus ringan.
Effect of heat treatment and storage on anthocyanins levels in food plants
Authors: Koldaev V. M. , Manyakhin A. Yu. 
Published: June 2022

Introduction: Anthocyanins, the polyphenolic plant pigments, have high antioxidant activity (AOA), reduce the risks of many pathological conditions in the human body. However, the wide medical and preventive use of anthocyanins is limited by their degradation during processing of plant raw materials. The objective of the work was to study the anthocyanins’ stability by spectrophotometric method during heat treatment and storage of vegetable and berry plants.Study objects and methods: Purple potatoes, eggplants, red cabbage, purple carrots, blue onions, red raspberries and blue honeysuckle were used in the study. Anthocyanins’ stability was determined by numerical values of extracts’ absorption spectra from the studied plants.Results and discussion: High stability indices of 0.623–0.986 were obtained for the anthocyanins of purple carrots, blue onion bulbs or red cabbage leaves whose main component is the antioxidant cyanidin with a relative AOA equal to 3.49. Low stability indices of 0.229-0.23 were obtained for anthocyanins of red raspberry berries and purple potato tubers containing pelargonidin or malvidin with 2.49–3.36 times lower relative AOA than for cyanidin. A regular correlation between stability and AOA of anthocyanins with a rank correlation coefficient of 0.91 (p<0.05) was established.It was established that during three months of storage in a domestic refrigerator, the content of anthocyanins in purple carrots and purple potatoes decreased by 10–15% of the initial one, and this decrease was 2-3 times greater when other studied plants were stored for 1.5–2 months.Conclusion: It is advisable to use the developed spectrophotometric methods in the express-analysis at selection of perspective plants for industrial cultivation as raw material for anthocyanin-containing herbal formulation.