bluuebunny/crossref_metadata_2025_split huggingface dataset:
Microcephaly as a risk factor for dental alterations: A case‐control study
Authors: Gomes Patrícia Nóbrega , Azevedo Isabelita Duarte , do Amaral Beatriz Aguiar , Arrais Nivia Maria Rodrigues , Lima Kenio Costa de 
Published: March 2022

AbstractObjectiveThis study aimed to assess whether microcephaly is a risk factor for alterations in the chronology and sequence of tooth eruption and for developmental defects of enamel.Matherials and MethodsIn this case‐control study, 81 children aged 30–36 months, including 40 normoreactive children and 41 with microcephaly, were submitted to oral clinical examination to determine the frequency of alterations in the chronology and sequence of tooth eruption and developmental enamel defects. The sample was matched for sex and age (1:1) and allocated to the case (presence of dental alterations) and control (absence of dental alterations) groups. Gestational age, birthweight and socioeconomic characteristics were also analyzed. Chi‐square test and Fisher's exact test were applied (α = 0.05).ResultsMicrocephaly was significantly associated with delayed tooth eruption, alterations in the sequence of tooth eruption, and defects in dental enamel (p < 0.001). Low birthweight also showed a significant association with this alterations (p < 0.005) and prematurity was associated with defects in enamel development (p < 0.005).ConclusionMicrocephaly is a risk factor for alterations in the tooth eruption process and enamel formation in primary teeth.
An Updated Meta‐Analysis of Randomized Controlled Trials on Total Hip Arthroplasty through SuperPATH versus Conventional Approaches
Authors: Ramadanov Nikolai 
Published: March 2022

The object was to conduct a systematic review and meta‐analysis of randomized controlled trials (RCTs) up to the present to draw reliable conclusions in the comparison between short‐term outcomes of total hip arthroplasty (THA) through supercapsular percutaneously assisted approach in THA (supercapsular percutaneously‐assisted total hip (SuperPATH)) versus conventional approaches (CAs). A systematic literature search was performed to identify RCTs comparing primary and secondary outcomes of THA through SuperPATH vs. CAs. Mean differences (MDs) were calculated for continuous outcomes and odds ratios (ORs) for dichotomous outcomes, using the DerSimonian and Laird method, the Mantel–Haenszel method and random effects model. A total of 14 RCTs involving 1021 patients met the inclusion criteria. Primary outcomes: SuperPATH reduced intraoperative blood loss (MD = −61.4, 95% CI −119.1 to −3.8). SuperPATH increased Harris hip score (HHS) 3, 6 and 12 months postoperatively (MD = 2.4, 95% CI 0.6–4.2; MD = 2.1, 95% CI 0.6–3.6; MD = 0.7, 95% CI 0.1–1.3; resp.). Both approaches did not differ in postoperative complication rates (OR = 0.7, 95% CI 0.2–3.3). Secondary outcomes: SuperPATH reduced pain visual analogue scale (VAS) 1 day and 3 days postoperatively (MD = −1.0, 95% CI −1.8 to −0.2; MD = −1.2, 95% CI −1.8 to −0.5; resp.). SuperPATH reduced incision length (MD = −5.2, 95% CI −7.0 to −3.4). SuperPATH increased operation time (MD = 14.3, 95% CI 3.7–24.8). Both approaches did not differ relevantly in acetabular cup inclination (MD = −1.8, 95% CI −3.8–0.2) and acetabular cup anteversion (MD = −0.6, 95% CI −1.2 to −0.1) angles. The overall findings of this meta‐analysis (Meta‐SuCAs‐2) suggested that the short‐term outcomes of THA through SuperPATH were superior to CAs. In the primary outcome, SuperPATH had a lower intraoperative blood loss and a higher HHS. Both approaches did not differ in postoperative complications. In the secondary outcome, SuperPATH had a lower pain VAS and a shorter incision length. Both approaches showed sufficient results in acetabular cup positioning. CAs had a shorter operation time than SuperPATH.
De novo phasing resolves haplotype sequences in complex plant genomes
Authors: Guk Ji‐Yoon , Jang Min‐Jeong , Choi Jin‐Wook , Lee Yeon Mi , Kim Seungill 
Published: March 2022

SummaryGenome phasing is a recently developed assembly method that separates heterozygous eukaryotic genomic regions and builds haplotype‐resolved assemblies. Because differences between haplotypes are ignored in most published de novo genomes, assemblies are available as consensus genomes consisting of haplotype mixtures, thus increasing the need for genome phasing. Here, we review the operating principles and characteristics of several freely available and widely used phasing tools (TrioCanu, FALCON‐Phase, and ALLHiC). An examination of downstream analyses using haplotype‐resolved genome assemblies in plants indicated significant differences among haplotypes regarding chromosomal rearrangements, sequence insertions, and expression of specific alleles that contribute to the acquisition of the biological characteristics of plant species. Finally, we suggest directions to solve addressing limitations of current genome‐phasing methods. This review provides insights into the current progress, limitations, and future directions of de novo genome phasing, which will enable researchers to easily access and utilize genome‐phasing in studies involving highly heterozygous complex plant genomes.
Effectiveness of a telephone‐based nursing intervention to reduce hospital utilization by COVID‐19 patients
Authors: Korycinski Samantha , Metcalf David , Keteyian Courtland 
Published: March 2022

AbstractObjectiveDetermine the effectiveness of a COVID‐19 remote monitoring and management program in reducing preventable hospital utilization.DesignA retrospective cohort study utilizing data from electronic health records.SampleTwo hundred ninety‐three patients who tested positive for COVID‐19 at a drive‐through testing site in Michigan. [Correction added on 11 April 2022, after first online publication: In the preceding sentence, “Two hundred and ninety‐third” has been corrected to “Two hundred ninety‐three” in this version.] The intervention group, consisting of 139 patients, was compared to a control group of 154 patients.MeasurementsThe primary outcome was the 30‐day probability of hospital utilization. The covariates included in the analysis were age, gender, tobacco use, body mass index (BMI), race, and ethnicity.InterventionA nurse‐led, telephone‐based active management protocol for COVID‐19 patients who were isolating at home.ResultsThe intervention group had a non‐statistically significant 42% reduction in risk of hospital utilization within 30 days of a positive COVID‐19 test when compared to the control group (HR = 0.578, p‐value .111, HR 95% CI [0.29, 1.13]).ConclusionsA nurse‐led remote monitoring and management program for COVID‐19 reduced the probability of 30‐day hospital utilization. Although the findings were not statistically significant, the program yielded practical significance by reducing hospital utilization, in‐person interaction, and the risk of infection for healthcare workers.
Prediction of gestational age based on foetal ultrasonographic biometric measurements in light breed horses
Authors: Renaudin Catherine D. , Kass Philip H. , Bruyas Jean‐Francois 
Published: March 2022

AbstractA table was generated, based on foetal ultrasonographic measurements in light breed mares, for each day of gestation beginning with day 100, to provide the predicted value of four biometric parameters: biparietal diameter (BPD), eye approximated volume (EyV), foetal aortic diameter (AortD) and femur length (FL). Using this table, day of gestation was successfully predicted in 23 Quarter Horses (QH) with known mating or ovulation dates. BPD, EyV and FL were the best foetal age predictors between 100‐ and 200‐days gestation predicting within 2 weeks of the actual day of gestation, while BPD and EyV were best between 200 and 300 days (within 3 weeks), and EyV was best after 300 days (within 3 weeks).
Production Behavior Evaluation on Inclined Well in Commingled Carbonate Gas Reservoir With Multiple Heterogeneous Layers Without Crossflow
Authors: Meng Fankun , Yan Haijun , He Dongbo , Liu Xiaohua , Li Qian , Deng Hui 
Published: March 2022

Abstract
To estimate production behaviors of inclined well in multilayer heterogeneous carbonate gas reservoir, two semi-analytical models for different formation distribution patterns are proposed, which are named as model I and model II. For model I, the inner region of each layer is fractured-vuggy porous medium, while the outer region only contains matrix. For model II, the inner and outer regions are consisted of matrix and fractured-vuggy porous mediums, respectively. To solve the model, Laplace transformation, Fourier transformation and inversion, Duhamel convolution, and Stehfest numerical inverse are applied. The validities of these models are verified through the comparisons with the published datum, which include well bottom-hole pressure (BHP) and gas production rate of individual layer for vertical and inclined wells in multilayer homogenous gas reservoir. Furthermore, by matching the well BHP data collected from a field case, the applicability of model is validated. The influences of prevailing factors, such as the radius ratio between inner and outer regions, horizontal–vertical permeability ratio, and inclination angle, on production behaviors are analyzed. The results show that influenced by the diverse formation distribution patterns, the variation of radius ratio between inner and outer regions has opposite effect on the well BHP for models I and II. Formation anisotropy and inclination angle have minimal effects on the well BHP of model I, but have significant impacts on model II. To keep the well BHP with a relatively high value, for model I and model II, the penetrate inclination angles should be greater than 50 deg and 55 deg, respectively.
Topology Optimization of Graded Truss Lattices Based on On-the-Fly Homogenization
Authors: Telgen Bastian , Sigmund Ole , Kochmann Dennis M. 
Published: March 2022

Abstract
We introduce a computational framework for the topology optimization of cellular structures with spatially varying architecture, which is applied to functionally graded truss lattices under quasistatic loading. We make use of a first-order homogenization approach, which replaces the discrete truss by an effective continuum description to be treated by finite elements in a macroscale boundary value problem. By defining the local truss architecture through a set of Bravais vectors, we formulate the optimization problem with regards to the spatially varying basis vectors and demonstrate its feasibility and performance through a series of benchmark problems in 2D (though the method is sufficiently general to also apply in 3D, as discussed). Both the displacement field and the topology are continuously varying unknown fields on the macroscale, and a regularization is included for well posedness. We argue that prior solutions obtained from aligning trusses along the directions of principal stresses are included as a special case. The outlined approach results in heterogeneous truss architectures with a smoothly varying unit cell, enabling easy fabrication with a tunable length scale (the latter avoiding the ill-posedness stemming from classical nonconvex methods without an intrinsic length scale).
Impacts of late Miocene normal faulting on Yarlung Tsangpo River evolution, southeastern Tibet
Authors: Shen Tianyi , Wang Guocan , van der Beek Peter , Bernet Matthias , Chen Yue , Zhang Pan , Wang An , Cao Kai 
Published: March 2022

Abstract
The Jiacha Gorge in southeastern Tibet is the second-largest deeply incised gorge of the Yarlung-Tsangpo River, after the Tsangpo Gorge. A late Cenozoic N-S–trending normal fault, the Woka Rift fault, coincides with the western limit of the gorge. However, the relationship between the formation of the gorge, drainage evolution, and rift activity remains unclear. Analysis of the river long profile suggests that the Jiacha Gorge developed as a ~45-km-wide knickzone, rather than a local knickpoint. Projection of tributary stream profiles indicate significantly deeper incision in the gorge than in the downstream area, suggesting different controls on incision. Thermochronological data collected along two age-elevation profiles in the Woka Rift footwall and the Jiacha Gorge record rapid cooling at ca. 12–10 Ma followed by moderate cooling between ca. 10 and 7 Ma, with additional accelerated cooling after ca. 5 Ma in the gorge. We interpret late Miocene (ca. 12–10 Ma) rapid cooling to reflect the onset of east-west extension and normal faulting along the Woka Rift, whereas the Pliocene (post–ca. 5 Ma) accelerated cooling is inferred to be driven by river incision in the Jiacha Gorge. Geomorphic and sedimentologic observations suggest diversion of the Yarlung-Tsangpo River through the Jiacha Gorge, from an earlier more southerly course, after the onset of rifting. Therefore, we suggest that normal faulting of the Woka Rift anchored the Jiacha Gorge knickzone on its shoulder, while footwall uplift and drainage diversion led to enhanced incision, forming the steepest channel upstream of the Tangpo Gorge along the Yarlung-Tsangpo River.
A composite Llandovery δ13Ccarb record from the Michigan Basin, USA
Authors: Al-Musawi Mohammed , Kaczmarek Stephen E. , Harrison William B. , Voice Peter J. , Kuglitsch Jeffrey J. , Griffith Elizabeth M. , Saltzman Matthew R. 
Published: March 2022

Abstract
A new high-resolution, composite δ13Ccarb curve for the Michigan Basin, USA, was constructed using two stratigraphically overlapping subsurface cores that span the complete Llandovery interval. The Llandovery succession of the Michigan Basin measures between 140 m and 265 m thick and is represented by three lithostratigraphic groups: the Cataract (Manitoulin formation and Cabot Head Shale), the Burnt Bluff (Lime Island, Byron, and Hendricks formations), and the Manistique (Schoolcraft and Cordell formations). The composite δ13Ccarb curve exhibits five positive carbon isotope excursions (CIEs). Conodont and 87Sr/86Sr data suggest that the CIEs correlate with the Hirnantian, Early Aeronian, Late Aeronian, Valgu, and Ireviken global excursions. The new composite δ13Ccarb curve from the Michigan Basin represents the most stratigraphically complete, single-basin Llandovery record worldwide. The composite δ13Ccarb curve permits the ages of three Llandovery lithostratigraphic groups to be chronostratigraphically determined within ca. 1 Ma resolution. The composite δ13Ccarb curve also implies that the Ordovician–Silurian boundary in the Michigan Basin is located at the top of the Manitoulin formation and not at the base of the Manitoulin formation, which is consistent with recent findings from Manitoulin Island, Ontario. From the regional perspective, the high-resolution composite δ13Ccarb curve provides a valuable tool for delineating the depositional history of the Michigan Basin during the Llandovery. From a global perspective, the new composite δ13Ccarb curve sheds light on the dynamics of the global carbon cycle, particularly during the Rhuddanian, which is rarely preserved in other carbonate basins worldwide.
МС2Е: The Meta-Cloud Computing Environment for Interdisciplinary Studies
Authors: Smelyanskii R. L. 
Published: March 2022

AbstractThe Meta-Cloud Computing Environment (MC2E) is a Russian‒Chinese project dedicated to the study of methods and tools for building an information and computing environment for scientific computational experiments and interdisciplinary research, which ended in 2020. Work in this area was focused on the federation principle of organizing computations and data management, providing for the creation of a specialized heterogeneous ecosystem of data centers with virtualized infrastructure and high-performance computers, united by telecommunication resources—a data transmission network. One of the key problems of building such an ecosystem, central to the MC2E project, is the integration of high-performance computers and data processing centers—cloud computing environments based on server clusters. A brief overview of the main results of the project are presented.
Rare Earth Elements in Soils of the Central Forest State Nature Biosphere Reserve
Authors: Antonova S. A. , Ladonin D. V. 
Published: March 2022

Abstract
The total content of rare earth elements (REEs) and the content of their oxalate-soluble fraction were studied in four soil profiles (Gleyic Umbrisols, Albic Gleyic Folic Retisols (Raptic), Dystric Albic Retisol) of the Central Forest Nature Reserve. The REE content was normalized to a local standard (the Russian Platform clay), and the cerium and europium anomalies were quantified [8]. In addition to the initial redistribution of REEs during the formation of rocks, REEs in the studied soils undergo geochemical fractionation, which results in the depletion of soil horizons of heavy lanthanides and europium. The negative europium anomaly is maximal in eluvial horizons and is weaker or absent in organic horizons. The oxalate-soluble REE fraction affects the redistribution of heavy lanthanides and cerium in the studied soils, and also results in the development of a positive cerium anomaly in some horizons.
Determining Sport Concussion Assessment Tool fifth Edition (SCAT5) reliable change in male professional hockey players
Authors: Bruce Jared M , Meeuwisse Willem , Hutchison Michael G , Comper Paul , Echemendia Ruben J 
Published: March 2022

ObjectivesThe purpose of this paper is to provide reliable change metrics and assess the test–retest psychometrics of the Sport Concussion Assessment Tool fifth Edition (SCAT5) in a multilingual sample of professional ice hockey players.MethodsThe SCAT5 was administered to National Hockey League and American Hockey League male professional ice hockey players as part of the 2018 and 2019 season medical evaluations. We extracted data from an existing clinical database of players who were administered two consecutive baseline evaluations and had no intervening concussions to assess psychometric properties (eg, test–retest reliability) and develop reliable change metrics.ResultsOverall, 1007 players met inclusion criteria. Players were reassessed on average 344.52 (±62.52) days following their first baseline. Test–retest reliability ranged from r=0.3 to r=0.5. Reliable change metrics for Immediate Memory varied considerably dependent on form order. Significant differences were found between English versus non-English language preference on Immediate Memory and Concentration but not Delayed Memory or the modified Balance Error Scoring System (mBESS). Reliable change indices at the 90% CI were: Symptom Severity (5), Total Symptoms (3), Immediate Memory (3-8), Concentration (2), mBESS (5) and Delayed Memory (2-4).ConclusionsOur findings highlight the importance of considering form differences and language preference when determining reliable change from baseline on the SCAT5 in male professional hockey players. The relatively modest test–retest reliability of the measures leaves room for improved psychometric properties and increased sensitivity to concussion in future iterations of the SCAT.
Association between resident status and patients’ experiences of primary care: a cross-sectional study in the Greater Bay Area, China
Authors: Wu JingLan , Liu RuQing , Shi Leiyu , Zheng Lingling , He Ning , Hu Ruwei 
Published: March 2022

ObjectivesPatients’ experiences are important part of health services quality research, but it’s still unclear whether patients’ experiences are influenced by resident status. This study aimed to evaluate the association between resident status and patients’ primary care experiences with the focus on migrants vs local residents.DesignA cross-sectional study using multistage cluster random sampling was conducted from September to November 2019. The data were analysed using general linear models.SettingSix community health centres in Guangzhou, China.Participants1568 patients aged 20 years or older.Main outcome measuresPatients’ primary care experiences were assessed using the Primary Care Assessment Tool. The 10 domains included in Primary Care Assessment Tool (PCAT) refers to first contact-utilisation, first contact-access, ongoing care, coordination (referral), coordination (information), comprehensiveness (services available), comprehensiveness (services provided), family-centredness, community orientation and cultural competence from patient’s perspective.Results1568 questionnaires were analysed. After adjusting for age, sex, education, annual family income, self-perceived health status, chronic condition, annual medical expenditure and medical insurance, the PCAT total scores of the migrants were significantly lower than those of local residents (β=−0.128; 95% CI −0.218 to −0.037). Migrants had significantly lower scores than local residents in first contact utilisation (β=−0.245; 95% CI −0.341 to −0.148), ongoing care (β=−0.175; 95% CI −0.292 to −0.059), family-centredness (β=−0.112; 95% CI −0.225 to 0.001), community orientation (β=−0.176; 95% CI −0.286 to −0.066) and cultural competence (β=−0.270; 95% CI −0.383 to −0.156), respectively.ConclusionPrimary care experiences of migrants were significantly worse off than those of local residents, especially in terms of primary care utilisation, continuity and cultural competence. Given the wide disparity in primary care experiences between migrants and local residents, Chinese healthcare system reform should focus on improving quality of primary care services for migrants, overcoming language barriers and creating patient-centred primary care services.
Paediatric injury in Beirut: a multicentre retrospective chart review study
Authors: Al-Hajj Samar , Ariss Abdel-Badih , Bachir Rana , Helou Mariana , Zaghrini Elie , Fatouh Fathalla , Rahme Rachid , El Sayed Mazen J 
Published: March 2022

ObjectiveThis study aims to assess the epidemiology of paediatric injury in Beirut, giving insights into their characteristics, contributing risk factors and outcomes.Design and settingA retrospective study was conducted to review medical charts for children aged 0–15 years presented to five hospital emergency departments (ED) located in Beirut over a 1-year period (June 2017–May 2018).ParticipantsA total of 1142 trauma-related visits for children under 15 years of age were included. A descriptive analysis and a bivariate analysis were performed to investigate admitted and treated/discharged patients.Primary outcomeA logistic regression was conducted to identify factors associated with hospital admission among injured children.ResultsA total of 1142 cases of paediatric injury ED cases were sampled, mean age was 7.7±4.35 years. Children aged 0–5 years accounted for more than one-third of the total cases, 40.0% (206/516) of the fall injuries and 60.1% (220/366) of home injuries. The leading cause of paediatric injury was fall (45.2%), nearly 4.1% of the cases were admitted to hospitals. Factors associated with admission included injury to abdomen (OR=8.25 (CI 1.11 to 61.24)), to upper extremity (OR=5.79 (CI 2.04 to 16.49)), to lower extremity (OR=5.55 (95% CI 2.02 to 15.20) and other insurance type (OR=8.33 (CI 2.19 to 31.67)). The three types of injuries mostly associated with hospital admission were fracture (OR=13.55 (CI 4.77 to 38.44)), concussion (OR=13.60 (CI 2.83 to 65.41)) and organ system injury (OR=31.63 (CI 3.45 to 290.11)).ConclusionsInjury remains a major health problem among the paediatric population in Lebanon. Parental child safety educational programmes and age-targeted injury prevention strategies should be initiated and implemented to mitigate the burden of child injuries and improve child safety and well-being.