bluuebunny/crossref_metadata_2025_split huggingface dataset:
Successful Use of a 5G-Based Robot-Assisted Remote Ultrasound System in a Care Center for Disabled Patients in Rural China
Authors: Chai Hui-hui , Ye Rui-zhong , Xiong Lin-fei , Xu Zi-ning , Chen Xuan , Xu Li-juan , Hu Xin , Jiang Lian-feng , Peng Cheng-zhong 
Published: July 2022

BackgroundDisability has become a global population health challenge. Due to difficulties in self-care or independent living, patients with disability mainly live in community-based care centers or institutions for long-term care. Nonetheless, these settings often lack basic medical resources, such as ultrasonography. Thus, remote ultrasonic robot technology for clinical applications across wide regions is imperative. To date, few experiences of remote diagnostic systems in rural care centers have been reported.ObjectiveTo assess the feasibility of a fifth-generation cellular technology (5G)-based robot-assisted remote ultrasound system in a care center for disabled patients in rural China.MethodsPatients underwent remote robot-assisted and bedside ultrasound examinations of the liver, gallbladder, spleen, and kidneys. We compared the diagnostic consistency and differences between the two modalities and evaluated the examination duration, image quality, and safety.ResultsForty-nine patients were included (21 men; mean age: 61.0 ± 19.0 [range: 19–91] years). Thirty-nine and ten had positive and negative results, respectively; 67 lesions were detected. Comparing the methods, 41 and 8 patients had consistent and inconsistent diagnoses, respectively. The McNemar and kappa values were 0.727 and 0.601, respectively. The mean duration of remote and bedside examinations was 12.2 ± 4.5 (range: 5–26) min and 7.5 ± 1.8 (range: 5–13) min (p &lt; 0.001), respectively. The median image score for original images on the patient side and transmitted images on the doctor side was 5 points (interquartile range: [IQR]: 4.7–5.0) and 4.7 points (IQR: 4.5–5.0) (p = 0.176), respectively. No obvious complications from the examination were reported.ConclusionsA 5G-based robot-assisted remote ultrasound system is feasible and has comparable diagnostic efficiency to traditional bedside ultrasound. This system may provide a unique solution for basic ultrasound diagnostic services in primary healthcare settings.
Argument mining as rapid screening tool of COVID-19 literature quality: Preliminary evidence
Authors: Brambilla Gianfranco , Rosi Antonella , Antici Francesco , Galassi Andrea , Giansanti Daniele , Magurano Fabio , Ruggeri Federico , Torroni Paolo , Cisbani Evaristo , Lippi Marco 
Published: July 2022

BackgroundThe COVID-19 pandemic prompted the scientific community to share timely evidence, also in the form of pre-printed papers, not peer reviewed yet.PurposeTo develop an artificial intelligence system for the analysis of the scientific literature by leveraging on recent developments in the field of Argument Mining.MethodologyScientific quality criteria were borrowed from two selected Cochrane systematic reviews. Four independent reviewers gave a blind evaluation on a 1–5 scale to 40 papers for each review. These scores were matched with the automatic analysis performed by an AM system named MARGOT, which detected claims and supporting evidence for the cited papers. Outcomes were evaluated with inter-rater indices (Cohen's Kappa, Krippendorff's Alpha, s* statistics).ResultsMARGOT performs differently on the two selected Cochrane reviews: the inter-rater indices show a fair-to-moderate agreement of the most relevant MARGOT metrics both with Cochrane and the skilled interval scores, with larger values for one of the two reviews.Discussion and conclusionsThe noted discrepancy could rely on a limitation of the MARGOT system that can be improved; yet, the level of agreement between human reviewers also suggests a different complexity between the two reviews in debating controversial arguments. These preliminary results encourage to expand and deepen the investigation to other topics and a larger number of highly specialized reviewers, to reduce uncertainty in the evaluation process, thus supporting the retraining of AM systems.
Did States With More Social Capital Pre-pandemic Offer Mental Health Protection During the COVID-19 Pandemic? A Cross-Sectional View
Authors: Dauner Kim Nichols , Wilmot Neil A. 
Published: July 2022

BackgroundSocial capital is a well-known health determinant with both relational and geographic aspects. It can help mitigate adverse events and has been shown to impact behaviors and responses during the COVID-19 pandemic. Mental health has declined during the COVID-19 pandemic, and social capital, may serve to buffer those declines.MethodsBuilding from this, we assessed whether pre-pandemic social capital and contemporaneous social policy, which included indicators of social trust, civic participation, and presence of mask mandates, affected pandemic mental health, measured as the percent of the population experiencing symptoms of depression and anxiety at the state level.ResultsGeneralized social trust and state mask mandates were significantly associated with lower levels of depression and anxiety. Conversely, states with greater civic engagement prior to the pandemic experienced more anxiety and depression.ConclusionsFindings suggest that existing social capital, particularly social trust, may protect against anxiety and depression and contribute to community resilience during times of adversity. States should invest in policies and programs that increase social trust.
Simultaneous Retrieval of Trace Gases, Aerosols, and Cirrus Using RemoTAP—The Global Orbit Ensemble Study for the CO2M Mission
Authors: Lu Sha , Landgraf Jochen , Fu Guangliang , van Diedenhoven Bastiaan , Wu Lianghai , Rusli Stephanie P. , Hasekamp Otto P. 
Published: July 2022

In support of the Copernicus Anthropogenic Carbon Dioxide Monitoring (CO2M) mission, this study evaluates the performance of the Remote sensing of Trace gas and Aerosol Product (RemoTAP) algorithm based on synthetic orbit measurements of realistic atmospheric and geophysical scenes over land. To make use of the added value of the multi-angle polarimeter (MAP) aboard the CO2M mission, the RemoTAP algorithm is developed to perform simultaneous retrieval of trace gas and aerosol properties from both MAP and CO2 imager (CO2I) measurements. At the same time, it has the capability to perform the retrieval of trace gas from only CO2I measurements. To set up the baseline tests, we apply a simple filter based on non-scattering retrievals in different CO2I bands which is able to filter out 80% of the cirrus-contaminated pixels, and after posterior filtering based on goodness of fit, 95% of the cirrus-contaminated cases are screened out. The MAP-CO2I retrieval method is able to reduce the aerosol-induced retrieval error in column-averaged dry-air mole fraction of CO2 (XCO2) in terms of RMSE and bias by more than a factor of 2, compared to CO2I-only retrievals on the filtered pixels. A strong correlation between XCO2 error and surface albedo in CO2I-only retrievals is significantly reduced for MAP-CO2I retrievals. Moreover, XCO2 biases in CO2I-only retrievals exhibit a significant spatiotemporal variability caused by a strong dependence on aerosol load. The biases can be up to 2 ppm over some regions, which are much larger than for the global case. It shows that only by the inclusion of MAP measurements, the large aerosol-induced biases can be mitigated, resulting in the retrievals that meet the mission requirement (precision <0.7 ppm and bias <0.5 ppm). The error estimates for XCO2 retrievals cover the uncertainties related to the instrument, aerosol, and cirrus, although other error sources, for example, in temperature and pressure profiles, may increase the overall error somewhat. The impact of cirrus on the retrieval, which can be significant, is also investigated. When not accounted for in the retrieval, the presence of a thin layer of cirrus with an optical thickness at 550 nm smaller than 0.3 can increase XCO2 errors by a factor of about 3 for MAP-CO2I retrievals, leading to an RMSE of 2.3 ppm for cirrus-contaminated scenes. When fitting cirrus properties, this can be reduced to 1.27 ppm for cirrus-contaminated cases. For CO2 retrievals using the proxy method, in a highly idealized situation where it is assumed that a perfect CH4 prior is available, an RMSE of 0.93 ppm and a bias of 0.3 ppm are achieved. These retrievals are hardly influenced by cirrus but depend linearly on the accuracy of the CH4 prior.
The efficacy and safety of paravertebral block for postoperative analgesia in renal surgery: A systematic review and meta-analysis of randomized controlled trials
Authors: Zhao You , Kan Yanan , Huang Xin , Wu Ming , Luo Weiping , Nie Jun 
Published: July 2022

BackgroundParavertebral block (PVB) has been widely used in postoperative analgesia, especially in thoracic and breast surgery. However, the efficacy and safety of PVB for analgesia after renal surgery remains uncertain. Therefore, this study aimed to determine the postoperative analgesic efficacy and safety of PVB in renal surgery.MethodsPubMed, Web of Science, Embase, and the Cochrane Library databases were systematically searched up to December 20, 2021. All randomized controlled trials (RCTs) evaluating the postoperative analgesic efficacy of PVB in renal surgery were collected. The meta-analysis was performed using RevMan 5.4 and Stata/MP 14.0 software.ResultsA total of 16 RCTs involving 907 patients were included in the meta-analysis. Ten studies investigated patients under percutaneous nephrolithotomy (PCNL), and six studies were done for patients under other renal surgery (nephrectomy or pyeloplasty). Compared with control groups (no block, sham block, or other nerve blocks), meta-analysis showed that PVB reduced 24-hour postoperative opioid consumption significantly (SMD = −0.99, 95%CI: −1.60–0.38, p = 0.001, I2 = 92%) and reduced pain scores at various time points within 24 h at rest and 1 h, 4 h, and 24 h at movement after renal surgery, furthermore, PVB prolonged the time to first postoperative analgesic requirement (SMD = 2.16, 95%CI: 0.94–3.39, p = 0.005, I2 = 96%) and reduced the incidence of postoperative additional analgesia (OR = 0.14, 95%CI: 0.06∼0.33, p &lt; 0.00001, I2 = 50%). Subgroup analysis revealed that the postoperative analgesia effect of PVB was more significant in PCNL, and the use of bupivacaine for PVB seemed to have a better performance. Besides, there was no difference in the incidence of postoperative nausea, vomiting, and itching between PVB and control groups.ConclusionThis study indicates that PVB may provide effective postoperative analgesia in patients under renal surgery, especially PCNL patients. Moreover, PVB is a safe analgesic method without significant analgesia-related complications.
Gender profile of principal investigators in a large academic clinical trials group
Authors: Luong Vi Thi Thao , Ho Cindy , Aedo-Lopez Veronica , Segelov Eva 
Published: July 2022

IntroductionGender equity in medicine has become a significant topic of discussion due to consistently low female representation in academia and leadership roles. Gender imbalance directly affects patient care. This study examined the gender and craft group of the Principal Investigators (PI) of clinical trials run by the Australasian Gastro-Intestinal Trials Group (AGITG)MethodsPublicly available data was obtained from the AGITG website. Trials were divided into upper, lower gastrointestinal cancer, miscellaneous (neuroendocrine and gastrointestinal stromal tumours). Where multiple PIs were listed, all were counted. Craft group was assigned as surgical, medical, radiation oncology or other.ResultsThere were 69 trials with 89 PI, where 52 trials were represented exclusively by male PIs. Of all PIs, 18 were women (20.2%); all were medical oncologists. Prior to 2005, all PIs were male. The craft group distribution of PIs was: 79% medical oncologists, 12% surgical oncologists, 8% radiation oncologist, 1% nuclear medicine physicians. Regarding trials with multiple PI's, there were 19 in total. Of these, 11 had only male PIs, which included 5 surgeons. Females were more likely to be a co-PI (42%) as opposed to sole PI (18%). There was no gender policy publicly available on the AGITG website.ConclusionsThere is a low percentage of female PIs in academic oncology trials in the portfolio of this large international trials group. No trial was led by a female surgical or radiation oncologist. There is a need to understand the reasons driving the disparity so that specific strategies can be put in place.
Exploring a Multi-Layer Coupled Network Propagation Model Based on Information Diffusion and Bounded Trust
Authors: Ju Chunhua , Wang Chenyu , Jiang Yihao , Bao Fuguang , Zhou Huajian , Xu Chonghuan 
Published: July 2022

Objective: To explore the law of opinion dissemination and individual opinion evolution at the micro level, this paper analyzes the influence of variation and oyster on communication from the perspective of network structure.Methods: In this paper, we introduce the concepts of “variation” and “oyster”, build a multi-layer coupled network environment combined with the ISOVR model, and conduct simulation experiments of network information dissemination based on the bounded trust model.Results: The experimental results reveal that the extent and scope of variation’s spread in the network are more dependent on the trust of nodes themselves, and decreasing the trust of nodes significantly reduces the rate and peak value of variation. Changing the silence coefficient of variation does not effectively change the direction of rumor propagation, which indicates that rumor has a strong propagation ability after mutation.Conclusion: The insights of this paper on the dissemination of public opinions include: 1) pay attention to people with high trust levels, such as opinion leaders; 2) clarify the misinformation in time to prevent further spread of rumors.
Identification of Male-Specific Molecular Markers by Recombination of RhoGEF10 Gene in Spotted Knifejaw (Oplegnathus punctatus)
Authors: Wu Yanduo , Xiao Yongshuang , Xiao Zhizhong , Ma Yuting , Zhao Haixia , Li Jun 
Published: July 2022

The spotted knifejaw (Oplegnathus punctatus) is a marine economic fish with high ecological value, food value, and fishing value, and its growth has obvious sex dimorphism. The rapid identification of its sex is beneficial to the development of sex determination and breeding. In this study, the method of comparative genomics and PCR amplification was used to further establish a rapid detection method for the recombinant RhoGEF10 gene in O. punctatus, which can quickly, accurately, and efficiently identify the sex of the O. punctatus to be tested. The homologous comparison results of male and female individuals showed that the DNA fragment length of the RhoGEF10 gene on the X1 chromosome was 326 bp, and the DNA fragment length on the Y chromosome was 879 bp. Therefore, it can be concluded that there is an insert fragment of 553 bp on the Y chromosome. PCR amplification results showed that the two DNA fragments of 879 bp and 326 bp were amplified in the Y chromosome and X1 chromosome of the male O. punctatus (X1X2Y), respectively, and the 879 bp fragment was a unique marker fragment of the recombinant RhoGEF10 gene; The female O. punctatus (X1X1X2X2) only a single DNA fragment of 326 bp was amplified. At the same time, the inserted fragment of the male individual resulted in partial inactivation of the RhoGEF10 protein, which in turn resulted in a slowing of peripheral nerve conduction velocity and thinning of the myelin sheath in male O. punctatus. The method shortens the time for accurate identification of the O. punctatus RhoGEF10 gene recombination and improves the detection efficiency. It is of great significance and application value in the research of nerve conduction and myelin development, male and female sex identification, the preparation of high male seedlings, and family selection based on the RhoGEF10 gene in the O. punctatus.
Índice de calidad de la harina de trigo de tres variedades (Cotacachi, Zhalao y Cojitambo) y su efecto en la comercialización
Authors: Enríquez Estrella Miguel , Cornelio Lopez Ricardo , Alberto Uvidia Hernan 
Published: July 2022

El presente trabajo de investigación tiene como objetivo medir los indicadores de calidad de la harina de trigo y su efecto en la comercialización, analizando las relaciones existentes entre estas de acuerdo a la NTE INEN 616; se utilizaron tres variedades (Cojitambo, Zhalao y Cotacachi) procedentes de tres lugares de producción del Ecuador (Chimbo, Alausí e Ibarra) luego de definir un proceso de obtención se procedió hacer el cálculo del % de impurezas mediante dos factores las impurezas y la humedad del grano, que para cada tratamiento fue de 2 kg, dándonos un promedio de pérdida del 5,26 %. Al generar la harina se realizaron los análisis fisicoquímicos, en los que encontramos que la variedad Zhalao en relación a la proteína es más elevada que las otras variedades, pero tiene un contenido bajo en grasa en relación a las otras dos variedades. Las variedades Cojitambo y Cotacachi mantienen una estrecha relación entre proteína, fibra y grasa, tomando en cuenta la región amazónica que es más húmeda no tenemos ningún cambio y eso lo demuestran las pruebas microbiológicas que están dentro de los parámetros requeridos en la norma. Al definirse la calidad como la excelencia o superioridad técnica de un determinado producto, que puede ser valorada, fijada y evaluada, esta variable toma importancia en la comercialización de este producto.

Palabras clave: Producto químico; empresa productivas; evaluación.
Turismo rural como contribución al desarrollo territorial de la parroquia Abdón Calderón de Portoviejo-Ecuador
Authors: Ponce Macias Miguel Angel , Loor Bravo Lucía , Plaza Macías Nila 
Published: July 2022

El turismo rural constituye una experiencia dentro de un contexto enriquecedor para los visitantes, en donde a través de una amplia gama de productos se vincula con actividades relacionadas a la naturaleza, la cultura y atractivos que atraen a los turistas. El objetivo de este trabajo fue analizar la importancia del turismo rural como contribución al desarrollo territorial, promocionando los espacios del turismo, concretándose la creación significativa de impulso del empleo y sobre todo el contacto con el entorno habitual. La metodología que se utilizó para la investigación, comprendió, un enfoque cualicuantitativo, el diseño escogido fue el no experimental, de tipo descriptiva, con un método propositivo, para la recolección de datos se utilizó una encuesta que se le aplicó a 20 dueños de negocios, concluyendo como base fundamental que el turismo rural en esta zona es una herramienta que aporta a su propio desarrollo.

Palabras clave: Cultura ancestral, desarrollo territorial, promoción, turismo rural.
Pelatihan Kewirausahaan dalam Meningkatkan Wawasan dan Keterampilan Berwirausaha Bagi Warga di Kelurahan Padang Harapan Kota Bengkulu
Authors: Supriyadi Dedi , Firmansyah Mas Agus , Marlina Neneng Cucu 
Published: July 2022

Tujuan pengabdian secara umum adalah untuk meningkatkan pengetahuan, keterampilan dan sikap peserta sasaran, serta untuk mengembangkan bakat seseorang, sehingga dapat melakukan pekerjaan sesuai dengan yang dipersyaratkan. Tujuan pengabdian ini adalah 1) untuk meningkatkan wawasan dan pengetahuan warga masyarakat, sehingga memiliki kemampuan untuk mengisi atau menangkap kesempatan berwirausaha pada warga masyarakat RT. 012/RW. 04 Kelurahan Padang Harapan Kecamatan Gading Cempaka Kota Bengkulu; 2) untuk meningkatkan keterampilan yang lebih efektif, sehingga akan menghasilkan produk/jasa kreatif yang lebih baik dan lebih cepat pada warga masyarakat di RT. 012/RW. 04 Kelurahan Padang Harapan Kecamatan Gading Cempaka Kota Bengkulu; 3) untuk mengembangkan sikap kepemimpinan, perilaku kemandirian, maka dengan sendirinya akan menimbulkan kemauan membangun networkingÂ (jaringan kerja sama) dengan pihak-pihak lain. Metode kegiatan Pengabdian, dilakukan secara bertahap, mulai dari (1) Sosialisasi kepada ketua RT dan warga masyarakat; (2) Pelatihan berupa penyuluhan wawasan dan pengetahuan kewirausahaan yang dilanjutkan dengan diskusi; (3) Praktek membuat produk olah yang berbahan baku jahe. Pertimbangan tema olah jahe ini, karena bahan baku jahe sangat banyak di Bengkulu, pasarannya relatif mudah. Variabel yang diukur adalah peningkatan wawasan, pengetahuan, keterampilan, sikap atau respon terhadap kegiatan. Evaluasi kegiatan pelatihan dapat dilihat ada peningkatan wawasan peserta. Dari beberapa pertanyaan pada awal kegiatan (pre-test), maka jawaban peserta hampir sama bahwa kewirausahaan identik dengan berjualan praktis. Setelah diberi penyuluhan tentang pengetahuan dan wawasan kewirausahaan, dievaluasi kembali (post-test) dengan pertanyaan yang sama, jawaban yang diperoleh sudah berubah wawasannya mengenai pengetahuan dan sikap memaknai terhadap kewirausahaan. Menurut mereka bukan hanya sebagai penjual atau pedagang saja, melainkan bidang jasa lainnya yang bergantung pada tujuan kewirausahaan yaitu memperoleh profitÂ yang berupa materi ekonomi dan kebermanfaatan (benefit) berupa wawasan kewirausahaan.
Partisipasi Masyarakat Dalam Implementasi Kebijakan Pencegahan Covid-19 di Kalurahan Nogotirto Kapanewon Gamping
Authors: Mawaddah Nuril , Khozin Muhammad 
Published: July 2022

Covid-19 pada awal tahun 2020 resmi dinyatakan sebagai wabah pandemi global yang berdampak pada semua sektor kehidupan oleh organisasi kesehatan dunia (WHO). Dalam pencegahan virus ini, partisipasi masyarakat merupakan hal yang penting. Masyarakat di Kalurahan Nogotirto, Kapanewon Gamping, Kabupaten Sleman turut ambil bagian dengan berpartisipasi aktif dalam upaya pencegahan Covid-19 dengan mentaati kebijakan dan anjuran yang ditetapkan pemerintah. Penelitian ini bermaksud untuk mengetahui partisipasi masyarakat dalam implementasi kebijakan pencegahan Covid-19 serta memberikan masukan kepada Pemerintah Kalurahan Nogotirto, Kapanewon Gamping, Kabupaten Sleman. Penelitian ini menggunakan pendekatan deskripti kualitatif dengan teknik pengambilan data secara observasional, wawancara dan dokumentasi. Adapun teknis analisis data yang digunakan adalah reduksi data, penyajian data dan penarikan kesimpulan. Berdasarkan hasil penelitian diketahui bahwa partisipasi masyarakat di Kalurahan Nogotirto Kapanewon Gamping, Kabupaten Slemansecara umum dapat dikatakan sudah baik meskipun keikutsertaan masyarakat belum maksimal. Â Bahkan sejumlah factor jugamenjadi penghambat dalam mewujudkan partisipasi ini, diantaranya adalah sifat fanatik masyarakat terhadap agama yang tidak percaya akan adanya covid-19. Sehingga masih diperlukan edukasi dan pendekatan-pendekatan tertentu yang harus dilakukan oleh Pemerintah.
Morphology of resorption of apical cement in destructive forms of periodontitis in the acute stage
Authors: Glinkin V. V. , Generalova Yu. A. , Bakaev Y. A. , Badalov F. V. , Demurova E. T. , Gorbatenko I. A. , Gracheva A. N. 
Published: July 2022

Aim. To study morphology of external resorption of apical root area of teeth with destructive forms of apical periodontitis in the acute stage.Materials and methods. Microrelief of 10 previously untreated teeth with destructive forms of apical periodontitis in the acute stage was investigated. The material was taken at the moment of dental manipulation of tooth extraction after injecting anesthesia with 2% lidocaine solution or Septanest if indicated with the information consent of the patient.Results. Damaged cement of heterogeneous structure with areas of resorption alternating with areas of undamaged cement in the area of the root tips was found. The resorbed cement looks like large lacunae with clearly outlined ribs, filled with rounded cell clusters – cementocytes.Conclusions. Resorbed tooth root cement of heterogeneous structure with different area and degree of destruction depth was found in the places of periodontal absence. In some cases the resorption of the root cement partially affected the inner area of the apical orifice.