bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical benefits of oral capecitabine over intravenous 5-fluorouracyl regimen in case of neoadjuvant chemoradiotherapy followed by surgery for locally advanced rectal cancer
Authors: Paszt Attila , Ottlakan Aurel , Abraham Szabolcs , Simonka Zsolt , Vas Marton , Maraz Aniko , Szepes Zoltan , Tiszlavicz Laszlo , Nyari Tibor , Olah Judit , Lazar Gyorgy 
Published: December 2022

Background: During the last decade, one of the most important treatment options for locally advanced, potencially resectable rectal tumours was neoadjuvant chemoradiotherapy (CRT) followed by surgery.Methods: Effects of the neoadjuvant treatment on surgical outcomes were retrospectively analysed in 185 patients with stage T2–T4 and N0–2, resectable rectal tumour among two patient groups defined by radiosensitizer agents. Group 1 (n = 94) involved radiotherapy (RT) with 50.4 Gy total dose (25 × 1.8 Gy + 3 × 1.8 Gy tumour bed boost), and intravenous 5-fluorouracil (5-FU) (350 mg/m2) with leucovorin (20 mg/m2) on the 1–5 and 21–25 days, while Group 2 (n = 91) RT and orally administrated capecitabine (daily 2 × 825 mg/m2) on RT days. Surgery was carried out after 8–10 weeks. Side effects, perioperative complications, type of surgery, number of removed regional lymph nodes, resection margins and tumour regression grade (TRG) were analysed.Results: More favourable side effects were observed in Group 2. Despite the same rate of diarrhoea (Group 1 vs. Group 2: 54.3% vs. 56.0%), Grade 2–3 diarrhoea ratio was lower (p = 0.0352) after capecitabine (Group 2). Weight loss occurred in 17.0% and 2.2% (p = 0.00067), while nausea and vomiting was described in 38.3% and 15.4% (p = 0.00045) with 5-FU treatment and capecitabine respectively. Anaemia was observed in 33.0% and 22.0% (p = 0.0941). Complete tumour regression occurred in 25.3% after oral- and 13.8% after intravenous treatment (p = 0.049). Ratio of sphincter preservation was higher with laparoscopy than open surgery (72.3% vs. 39.7%) (p = 0.00001).Conclusion: The study confirms advantages of neoadjuvant chemoradiotherapy with oral capecitabine for rectal tumours, such as more favourable side effect profile and overall clinical outcome, with increased rate of complete tumour regression.
Assessing the Cloud Adjacency Effect on Retrieval of the Ground Surface Reflectance from MODIS Satellite Data for the Baikal Region
Authors: Tarasenkov Mikhail V. , Engel Marina V. , Zonov Matvei N. , Belov Vladimir V. 
Published: December 2022

The cloud adjacency effect on surface reflectance retrievals for the region of the Russian Federation with coordinates 51–54∘ N, 103–109∘ E including the southern part of Lake Baikal for the period of 1–23 July 2021 is assessed in this paper. The method is based on the computer program for statistical simulation of radiative transfer in the atmosphere with the stochastic cloud field including a deterministic gap of a given radius. The results of this program are then used in the interpolation formula. Masks of cloudless pixels, for which the cloud adjacency effect (CAE) changes the ground surface reflectance by more than 0.005, are constructed. The analysis of the resulting CAE radii shows that the average radius is 13.7 km for MODIS band 8, 11.2 km for band 3, 8.4 km for band 4, 7.2 km for band 1, and 7 km for band 2. For the considered MODIS images and bands, the pixels with strong CAE make up from 2.8 to 100% of the total number of cloudless pixels. The correlation coefficients between the initial data and the CAE radius suggest that the cloud optical depth, cloud cover index, and ground surface reflectance exert the major influence on the considered images. A simplified approximation equation for the CAE radius as a function of the cloud optical depth, cloud cover index, and surface reflectance is derived. The analysis of the approximation shows that for the considered images, the CAE radius decreases nearly linearly with wavelength for low reflective surfaces. However, for high reflective surfaces, its wavelength dependence is nonlinear.
The Weissella Genus: Clinically Treatable Bacteria with Antimicrobial/Probiotic Effects on Inflammation and Cancer
Authors: Ahmed Sadia , Singh Sargun , Singh Vaidhvi , Roberts Kyle D. , Zaidi Arsalan , Rodriguez-Palacios Alexander 
Published: December 2022

Weissella is a genus earlier considered a member of the family Leuconostocaceae, which was reclassified into the family Lactobacillaceae in 1993. Recently, there have been studies emphasizing the probiotic and anti-inflammatory potential of various species of Weissella, of which W. confusa and W. cibaria are the most representative. Other species within this genus include: W. paramesenteroides, W. viridescens, W. halotolerans, W. minor, W. kandleri, W. soli, W. ghanensis, W. hellenica, W. thailandensis, W. fabalis, W. cryptocerci, W. koreensis, W. beninensis, W. fabaria, W. oryzae, W. ceti, W. uvarum, W. bombi, W. sagaensis, W. kimchi, W. muntiaci, W. jogaejeotgali, W. coleopterorum, W. hanii, W. salipiscis, and W. diestrammenae. Weissella confusa, W. paramesenteroides, W. koreensis, and W. cibaria are among the few species that have been isolated from human samples, although the identification of these and other species is possible using metagenomics, as we have shown for inflammatory bowel disease (IBD) and healthy controls. We were able to isolate Weissella in gut-associated bacteria (post 24 h food deprivation and laxatives). Other sources of isolation include fermented food, soil, and skin/gut/saliva of insects/animals. With the potential for hospital and industrial applications, there is a concern about possible infections. Herein, we present the current applications of Weissella on its antimicrobial and anti-inflammatory mechanistic effects, the predisposing factors (e.g., vancomycin) for pathogenicity in humans, and the antimicrobials used in patients. To address the medical concerns, we examined 28 case reports focused on W. confusa and found that 78.5% of infections were bacteremia (of which 7 were fatal; 1 for lack of treatment), 8 were associated with underlying malignancies, and 8 with gastrointestinal procedures/diseases of which 2 were Crohn’s disease patients. In cases of a successful resolution, commonly administered antibiotics included: cephalosporin, ampicillin, piperacillin-tazobactam, and daptomycin. Despite reports of Weissella-related infections, the evolving mechanistic findings suggest that Weissella are clinically treatable bacteria with emerging antimicrobial and probiotic benefits ranging from oral health, skin care, obesity, and inflammatory diseases to cancer.
FINANCIAL PERFORMANCE ANALYSIS USING ECONOMIC VALUE ADDED, FINANCIAL VALUE ADDED, AND RETURN ON ASSET IN PT. BUANA
Authors: Widya Widya , Harahap Sunarji , Elidawati Elidawati , Goh Thomas Sumarsan 
Published: December 2022

The company has goal of making profit so the company's performance increases well. The concept of measuring financial performance is done by making financial analysis such as measuring company finances with financial ratio analysis. Ratio analysis that can be used by companies is Economic Value Added (EVA), Financial Value Added (FVA), or Return On Assets (ROA).
This research technique is a comparative descriptive analysis technique. Primary data were collected and obtained through observational interviews, documentation studies and literature studies, secondary data obtained from literature related to the research topic. Financial reports as the object of research.
The results show the analysis of PT.BUANA's financial performance with EVA measurement has a positive increase from 2019 to 2020. Financial performance with EVA has a positive increase which can prove the company operates consistently. In profit, analysis of PT.BUANA's financial performance with the measurement of FVA experienced a negative decline from 2019 to 2020. A negative decline can prove the level of net income generated by the company cannot cover investment in assets in the company. Analysis of PT.BUANA's financial performance with ROA decreased in percentage from 2019 to 2020. This proves the company's ability to use capital and generate profits has decreased.
A estruturação das aulas de educação física no ensino médio brasileiro: uma revisão sistemática
Authors: De Lima dos Santos Thais , Brum dos Santos Any Gracyelle , Mendes Fumagalli Laura , Vilanova Ilha Phillip 
Published: December 2022

Resumo: O presente estudo teve como objetivo mapear estudos efetuados sobre a estruturação das aulas de Educação Física no Ensino Médio, a partir de uma revisão sistemática. Foram utilizadas, como fontes de informação para busca, as seguintes bases de dados eletrônicas: LILACS, Portal de Periódicos CAPES/MEC, Microsoft Academic. De acordo com os critérios de inclusão e exclusão adotados, 12 artigos contemplaram os requisitos adequados para a pesquisa. Os parâmetros analisados nos artigos foram os seguintes: autoria; ano de publicação; periódico; tipo de estudo; população-alvo; resultados relacionados com a estruturação das aulas de Educação Física no Ensino Médio. Empregou-se a análise de conteúdo para a análise dos dados. Evidenciou-se que as publicações dos artigos se deram em todo o período delimitado pelo presente estudo (16 anos). Os estudos revelam viés ao descrever a realidade das estruturas das aulas de Educação Física com características descritivas. Quanto à população dos estudos, detectou-se o predomínio de pesquisas envolvendo professores, mas verificou-se, também, a participação de alunos e gestores. No que tange à estrutura das aulas, observou-se a ocorrência dos esportes coletivos como conteúdos hegemônicos, abordagem tradicional de ensino, quase inexistência da interdisciplinaridade e espaços inadequados como principais características das aulas de Educação Física no Ensino Médio. E, consequentemente, altos índices de evasão e desinteresse pela disciplina. Espera-se, com o presente artigo, instigar mais estudos que possibilitem mostrar a realidade da Educação Física na escola a fim de aproximar pesquisadores e sujeitos pesquisados para que consigam dialogar, refletir sobre esses contextos.
Palavras-chave: Educação Física, Ensino Médio, Conteúdo.
Kata Serapan Bahasa Arab Dalam Bahasa Indonesia: Pendekatan Leksikografi
Authors: Raodhatul Jannah  , Herdah  
Published: December 2022

Perkembangan bahasa Indonesia tidak terlepas dari pengaruh bahasa-bahasa dari negara lain. Pengaruh tersebut nampak pada munculnya kosakata baru yang berasal dari bahasa lain, diantaranya bahasa Arab. Penulis memutuskan untuk melakukan penelitian tentang kata serapan bahasa Arab dalam bahasa Indonesia menggunakan pendekatan Leksikografi. Mengingat semua kosakata bahasa Indonesia termuat dalam KBBI yang dibukukan secara resmi dan digunakan secara menyeluruh oleh masyarakat Indonesia.
Penelitian ini bertujuan untuk mendeskripsikan kata serapan bahasa Arab dalam bahasa Indonesia melalui pendekatan leksikografi atau kamus. Oleh karena itu, penelitian ini dilakukan dengan menggunakan pendekatan kualitatif dan jenis penelitian adalah kajian Pustaka terhadap kosakata yang terdapat dalam Kamus Besar Bahasa Indonesia.
Kebutuhan masyarakat terhadap bahasa atau istilah asing sangat diperlukan, terutama istilah atau penulisan kata yang berasal dari bahasa Arab. Kosakata bahasa Indonesia yang berasal dari bahasa Arab cukup banyak, bahkan diperkirakan sekitar 2000-3000 kata. Kata serapan bahasa Arab dalam bahasa Indonesia ini dikelompokkan menjadi empat, yaitu kata serapan yang lafal dan faedahnya masih sesuai dengan aslinya, kata serapan yang lafalnya berubah namun maknanya tetap, kata serapan yang lafalnya sama namun maknanya berubah, serta kata serapan yang lafal dan faedahnya berubah dari lafal dan makna aslinya.
МЕТОДИЧНИЙ ПІДХІД ДО СКЛАДАННЯ ПРОГРАМ РОЗВИТКУ ПІДПРИЄМНИЦТВА НА БАЗОВОМУ РІВНІ В УМОВАХ ВІДНОВЛЕННЯ НАЦІОНАЛЬНОЇ ЕКОНОМІКИ
Authors: Шлафман Наталія , Бондаренко Олена 
Published: December 2022

У статті проведено дослідження чинної інституційної бази програмного регулювання розвитку МСП та виявлено великі розбіжності у фінансовій спроможності територіальних громад Одеської області (як прикладу розрахунку). Проведені дослідження дозволили удосконалити методичний підхід до складання програм розвитку підприємництва на базовому рівні в умовах відновлення національної економіки, який, на відміну від існуючого єдиного підходу до планування розвитку МСП, базується на врахуванні розбіжностей у соціально-економічній та фінансовій спроможності територіальних громад до розвитку та ролі МСП у соціально-економічному та екологічному розвитку.
ПОРІВНЯЛЬНА ХАРАКТЕРИСТИКА ЦИТОСТАТИЧНОЇ АКТИВНОСТІ ДЕЯКИХ ЙОДОВМІСНИХ, ЛЕКТИНОВМІСНИХ ТА АЛКАЛОЇДОВМІСНИХ РОСЛИН
Authors: Мегалінська Ганна , Страшко Станіслав , Білик Валентина , Даниленко Євген , Білик Жанна 
Published: December 2022

В роботі наведено дані експерименту по виченню цистостатичної активності йодовмісних, алкалоїдовмісних та лектиновмісних рослин. Об’єктами дослідження були: Zostera marina L., Xanthium strumarium L., Laminaria saccharina L., Vinca minor L., Viscum album L., Chelidonium majus L., Urtica dioica L. Результати порівняння експериментальних данних свідчать, що найбільш активними цитостатиками виступають йодовмісні рослини.
ЗВ’ЯЗКИ РОДИНИ САЦ З ЧЕРНІГІВЩИНОЮ
Authors: Морозова Анна 
Published: December 2022

Мета даного дослідження полягає у висвітлити основних віх життя представників родини творчої інтелігенції кінця ХІХ–ХХ ст. Саців. Мета висуває завдання: узагальнення біографічних даних про родину шляхом опрацювання архівних джерел, матеріалів у періодичних виданнях, науковій та популярній літературі, з’ясування обставин їхнього життя та діяльності у соціокультурному контексті епохи. Відповідно до мети добиралися і методи дослідження: загальнонаукові методи аналізу та дедукції, історико-хронологічний метод для вивчення та упорядкування подій і фактів біографій; джерелознавчий – для дослідження архівних джерел; та логіко-узагальнюючий метод – для підбиття підсумків. Наукова новизна полягає в тому, що доповнено і уточнено біографічні дані представників родини, серед яких переважають видатні представники різних видів мистецтв. Висновки. Уточнено дати життя представників родини Сац, встановлено їхні зв’язки з Чернігівщиною, з’ясувані причини прийняття ними православ’я. Застосування результатів дослідження у науковій, педагогічній та просвітницькій діяльності розширить уявлення про внесок уродженців Чернігівщини у розвиток світової культури.
Р. Я ЛУЦИК – ОРГАНІЗАТОР ФЕДОРІВСЬКОЇ ЗБІРКИ ЛЬВІВСЬКОЇ НАЦІОНАЛЬНОЇ НАУКОВОЇ БІБЛІОТЕКИ УКРАЇНИ ІМЕНІ В. СТЕФАНИКА
Authors: Зінько Оксана 
Published: December 2022

Колекція видань Івана Федорова ЛННБ України ім. В. Стефаника — одна з найцінніших і найповніших у книгосховищах нашої країни. Збережені у відділі рідкісної книги Бібліотеки видання Івана Федорова охоплюють львівський, заблудівський та острозький періоди друкарських осередків першодрукаря. Виокремлення із загальних фондів стародрукованих видань Бібліотеки, опрацювання та дослідження кириличних стародруків розпочав у 1950 р. Роман Ярославович Луцик (1900–1974) – книгознавець, магістр історії, керівник відділу рідкісної книги у 1950–1974 рр. Фонд кириличних стародруків, сформований з численних колекцій галицьких книгозбірень, на початку становлення відділу рідкісної книги був розпорошений і неопрацьований. Багатопримірниковість фонду кирилиці зобов’язувала Р. Я. Луцика до виявлення дублетів чи варіантів видань, встановлення комплектності стародруків, опису індивідуальних особливостей кожного примірника видання. Примірники федорівських друків переважно були дефектними, потребували докладної атрибуції, складних бібліографічних розшуків.
Metode Bermain di Lingkungan Pantai Sebagai Upaya Meningkatkan Kemampuan Lompat Tinggi Siswa Sekolah Menengah Pertama
Authors: Hayatunnufus Qanet , Kusuma Lalu Sapta Wijaya , Sucipto Eko 
Published: December 2022

Tujuan penelitian ini adalah untuk mengetahui hasil penerapan metode bermain di lingkungan pantai terhadap peningkatan hasil belajar lompat tinggi pada siswa kelas VIII B SMP Negeri 4 Taliwang. Metode penelitian ini menggunakan Penelitian Tindakan Kelas (PTK). Sampel dalam penelitian ini adalah siswa kelas VIII B SMP Negeri 4 Taliwang yang berjumlah 22 orang. Untuk pengumpulan data diperoleh dengan mengamati dan menguji hasil belajar siswa dengan instrumen tes berupa: (1) Penilaian Afektif, (2) Penilaian Kognitif, dan (3) Penilaian Psikomotor. Sedangkan teknik analisis data menggunakan pertanyaan langsung dengan taraf signifikansi 100%. Hasil penelitian mengungkapkan bahwa persentase kriteria hasil belajar siswa pada setiap siklus mengalami peningkatan yang baik. Siklus 1 rata-rata hasil belajar siswa untuk aspek kognitif, psikomotor dan afektif adalah 73,21. Sedangkan, siklus 2 rata-rata hasil belajar siswa untuk aspek kognitif, psikomotor dan afektif adalah 81,64. Kesimpulan dalam penelitian ini menunjukkan bahwa setelah penerapan metode bermain di lingkungan pantai dapat meningkatkan hasil belajar lompat tinggi pada siswa kelas VIII B SMP Negeri 4 Taliwang.
The Method of Playing in the Beach Environment as an Effort to Improve the Junior High School Students’ High Jumping Ability
Abstract
The purpose of this study was to determine the results of the implementation of the method of playing in a beach environment on improving high jump learning outcomes in class VIII B students of SMP Negeri 4 Taliwang. This research method uses Classroom Action Research. The sample in this study was class VIII B students of SMP Negeri 4 Taliwang, totaling 22 people. For data collection, it was obtained by observing and testing student learning outcomes with test instruments in the form of: (1) Affective Assessment, (2) Cognitive Assessment, and (3) Psychomotor Assessment. While the data analysis technique used direct questions with a significant level of 100%. The results of the study revealed that the percentage of student learning outcomes criteria in each cycle experienced a good increase. Cycle 1 the average student learning outcomes for cognitive, psychomotor and affective aspects is 73.21 while cycle 2 the average student learning outcomes for cognitive, psychomotor and affective aspects is 81.64. The conclusion of this study shows that after the application of the method of playing in a beach environment can improve high jump learning outcomes in class VIII B students of SMP Negeri 4 Taliwang.
Kesiapan Guru Pendidikan Jasmani Sekolah Menengah Pertama di Kabupaten Lombok Tengah dalam Pembelajaran Daring Selama Pandemi Covid-19
Authors: Jihad Dimas Alfaraby , Rindawan Rindawan , Prabowo Bangkit Yudho 
Published: December 2022

Penelitian ini bertujuan untuk mengetahui kesiapan guru pendidikan jasmani di sekolah menengah pertama di Kabupaten Lombok Tengah, khususnya Kecamatan Praya Timur dan Janapria dalam pembelajaran daring selama pandemi Covid-19. Desain penelitian ini menggunakan metode survey dengan teknik pengumpulan data menggunakan instrumen tes berupa angket. Populasi dalam penelitian adalah guru pendidikan jasmani yang berjumlah 30 orang, dengan teknik pengambilan sampling menggunakan studi populasi. Instrumen dalam penelitian ini berupa angket tertutup yang sudah disediakan jawabannya, sehingga responden tinggal memilih dengan memberikan tanda check list (?) pada kolom yang sesuai. Teknik analisis data yang digunakan dalam penelitian ini adalah teknik statistik deskriptif dengan persentase. Hasil penelitian kesiapan guru pendidikan jasmani di sekolah menengah pertama di Kabupaten Lombok Tengah, khususnya Kecamatan Praya Timur dan Janapria dalam pembelajaran daring selama pandemi Covid-19 berada pada kategori, sebagai berikut: (1) sangat siap sebanyak 2 orang dengan persentase 6,67%; (2) kategori siap sebanyak 7 orang dengan persentase 23,33%; (3) kategori cukup siap sebanyak 14 orang dengan persentase 46,67%; (4) kategori kurang siap sebanyak 5 orang dengan persentase 16,67%; dan (5) kategori sangat kurang siap sebanyak 2 orang dengan persentase 6,67%.
Readiness of Junior High School Physical Education Teachers in Central Lombok Regency in Online Learning During the Covid-19 Pandemic
Abstract
This study aims to determine the readiness of physical education teachers in junior high schools in Central Lombok Regency, especially East Praya and Janapria Districts in online learning during the Covid-19 pandemic. The design of this study used a survey method with data collection techniques using a test instrument in the form of a questionnaire. The population in this study was physical education teachers, totaling 30 people, with a sampling technique using a population study. The instrument in this study is in the form of a closed questionnaire whose answers have been provided, so that respondents only need to choose by giving a check list (?) in the appropriate column. Data analysis technique used in this research is descriptive statistical technique with percentage. The results of the research on the readiness of physical education teachers in junior high schools in Central Lombok Regency, especially East Praya and Janapria sub-districts in online learning during the Covid-19 pandemic were in the following categories: (1) very prepared as many as 2 people with a percentage of 6.67% ; (2) ready category as many as 7 people with a percentage of 23.33%; (3) the category is quite ready as many as 14 people with a percentage of 46.67%; (4) less ready category as many as 5 people with a percentage of 16.67%; and (5) very unprepared category as many as 2 people with a percentage of 6.67%.
Program Bimbingan Belajar Berdasarkan Profil Academic Self-Efficacy Santri (Studi Deskriptif di SMP IT Baitul Anshor Boarding School dan Pondok Pesantren Baitul Izzah Cimahi Tahun Ajaran 2018/2019)
Authors: Karimah Aulia , Simanjuntak Kristina , Atmadja Fitriani Putri 
Published: December 2022

Academic Self-Efficacy refers to one’s confidence and beliefs about their own abilities to accomplish task and academic demands. Santri or students in junior high school considered as adolescences and still need helps to develop their abilities in academic because their lack of confidences about their level on ability in academic domain. The purpose of this research is to find out about academic self-efficacy santri. The research approached is quantitative approach with descriptive method. Population in this study are santri from Junior High School Baitul Anshor Boarding School dan Baitul Izzah Boarding School academic year 2018/2019. The sample for this research consisted of 67 santri from Baitul Anshor Boarding School and 78 santri from Baitul Izzah Boarding School and using probability sampling with smple random sampling with 0.05 error level. The results of this research show that general overview is in medium category. The result form this research is guidance program that has been tested by the experts and guidance and counseling praticer or school counselor.
Türk Kadınının 1930 Belediye Seçimlerine Katılımı ve Bir Amerikan Diplomat Raporuna Yansımaları
Authors: BEDİR Ayşe 
Published: December 2022

1923-1938 yılları arasını kapsayan dönem, modern Türkiye’nin her alanda hızla yeniden yapılandırıldığı bir dönemdir. Şüphesiz ki dönemin kayda değer gelişmelerinden biri de kadınların elde ettikleri siyasi haklardır. Bu hakların ilki, kadınların 1930 Belediye Seçimleri’ne katılarak seçme ve seçilme hakkına kavuşmasıdır. Bu konu, başta Meclis olmak üzere, dönemin basınında ve çeşitli mecralarda müzakere edilmiş ve ayrıca Türkiye'de bulunan yabancı elçilik temsilcileri tarafından da dikkatle takip edilmiştir. Bu çalışmada, Tanzimat Dönemi’nden 1930 Belediye Seçimleri’ne kadar kadın haklarındaki tarihsel gelişmeler aktarılmış; bu çerçevede, söz konusu siyasi kazanımın Türkiye’de elçilik 3. Kâtibi Amerikan diplomatı David Williamson’ın raporuna nasıl yansıdığı irdelenmiştir. Raporun, kadınların 1930 seçimlerine katılımını ve gelecek seçimlere etkisini hafife aldığı ve yine raporun, diplomatın yer yer şahsi görüşlerini içermekle birlikte Türk yetkililerinin basın açıklamaları ve onlarla bizzat yapılan görüşmelere dayanarak hazırlandığı ve kamuoyu yoklaması niteliği taşıdığı görülmüştür. Raporda yer alan değerlendirme ve görüşler, arşiv belgeleri, resmi kaynaklar, dönemin süreli yayınları ve literatür çerçevesinde incelenmiştir.