bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perceived value and behavioral intentions toward dining at Chinese restaurants in Bangladesh: the role of self-direction value and price fairness
Authors: Hasan Abdulla Al-Towfiq 
Published: July 2022

PurposeThis paper investigates the effect of perceived value (hedonic value, utilitarian value, and conditional value) on customers’ behavioral intentions toward dining at Chinese restaurants in Bangladesh. Moreover, this study examines the mediating effect of self-direction value and the moderating effect of price fairness on the association between perceived value and behavioral intentions.Design/methodology/approachThe proposed model was empirically tested by collecting 390 useable responses from full-table service restaurants in Bangladesh via personal interview. Data were analyzed by testing the measurement model, predictive relevance, effect size and structural model using SMART PLS 3.FindingsThe research findings suggest that hedonic, utilitarian and conditional values significantly influence customers’ behavioral intentions toward dining at Chinese restaurants. Moreover, self-direction value partially mediates, and price fairness strongly moderates the linkage between perceived value and behavioral intentions.Practical implicationsThis sfloattudy offers useful insights for managers who want to know the factors influencing behavioral intentions toward dining at Chinese restaurants. The findings also assist restaurant practitioners in knowing that customers' perceived value via self-direction value (personal value) and price fairness strongly predict behavioral intentions.Originality/valueTo the best of the author’s knowledge, this research is the first attempt to delve into customers' behavioral intentions toward dining at Chinese restaurants with the proposed model.
Antarctic lake phytoplankton and bacteria from near‐surface waters exhibit high sensitivity to climate‐driven disturbance
Authors: Sherwell Shasten , Kalra Isha , Li Wei , McKnight Diane M. , Priscu John C. , Morgan‐Kiss Rachael M. 
Published: July 2022

AbstractThe McMurdo Dry Valleys (MDVs), Antarctica, represent a cold, desert ecosystem poised on the threshold of melting and freezing water. The MDVs have experienced dramatic signs of climatic change, most notably a warm austral summer in 2001–2002 that caused widespread flooding, partial ice cover loss and lake level rise. To understand the impact of these climatic disturbances on lake microbial communities, we simulated lake level rise and ice‐cover loss by transplanting dialysis‐bagged communities from selected depths to other locations in the water column or to an open water perimeter moat. Bacteria and eukaryote communities residing in the surface waters (5 m) exhibited shifts in community composition when exposed to either disturbance, while microbial communities from below the surface were largely unaffected by the transplant. We also observed an accumulation of labile dissolved organic carbon in the transplanted surface communities. In addition, there were taxa‐specific sensitivities: cryptophytes and Actinobacteria were highly sensitive particularly to the moat transplant, while chlorophytes and several bacterial taxa increased in relative abundance or were unaffected. Our results reveal that future climate‐driven disturbances will likely undermine the stability and productivity of MDV lake phytoplankton and bacterial communities in the surface waters of this extreme environment.
Toward an accurate mechanistic understanding of Wolbachia‐induced cytoplasmic incompatibility
Authors: Wang Wei , Cui Wen , Yang Haitao 
Published: July 2022

AbstractWolbachia are the most successful intracellular bacteria in arthropods. They can manipulate host reproduction to favour infected females, which transmit Wolbachia to their progeny and increase the presence of Wolbachia in the population. The reproductive alterations caused by Wolbachia include feminization, parthenogenesis, male killing and cytoplasmic incompatibility (CI), among which CI is the most common. CI leads to embryonic lethality when Wolbachia‐infected males mate with uninfected females or those infected with an incompatible strain. This lethality can be rescued if females are infected with a compatible strain. Although CI was described in the 1960s and its connection to Wolbachia was made in the 1970s, the genes responsible for CI, called CI factors, were not identified until recently. Since then, significant progress has been made in understanding the molecular mechanism of CI using a combination of genetic, phylogenetic, biochemical and structural approaches. The detailed molecular mechanisms behind this fascinating endosymbiotic bacteria‐induced phenotype have begun to emerge. Here, we summarize recent progress in understanding the molecular mechanism of CI, especially focusing on the recently solved CI factor structures and discussing what these new structures brought in terms of CI mechanism.
On the allocation puzzle and capital flows: Evidence from foreign direct investment and real sector growth in Africa
Authors: Asamoah Michael Effah , Alagidede Imhotep Paul , Adu Frank 
Published: July 2022

AbstractThis paper takes a new dimension on the foreign direct investment (FDI)–growth nexus through the lens of the allocation puzzle. We examine how the influx of FDI affects the broader economy through its impact on real economic sectors in a panel of 42 Sub‐Saharan African (SSA) countries over 1980–2017. Using a dynamic panel model and decomposing the real sector into its parts, we test for the possibility of a two‐way bi‐directional relationship between growth in agriculture, manufacturing, industry and service value additions, and FDI. There is no evidence of an allocation puzzle at the level of the real sector and the components parts, which suggests that SSA countries with relatively high growth in the real sector will attract more FDI. While the effect of FDI on the real sector is positive at the disaggregated level, there is a positive bi‐directional effect between FDI and growths in manufacturing, industry and service value additions. The results are robust to key determinants of the growth–FDI nexus.
The impact of Medicaid funding structures on inequities in health care access for Latinos in New York, Florida, and Puerto Rico
Authors: Rivera‐González Alexandra C. , Roby Dylan H. , Stimpson Jim P. , Bustamante Arturo Vargas , Purtle Jonathan , Bellamy Scarlett L. , Ortega Alexander N. 
Published: July 2022

AbstractObjectiveTo study the impact of Medicaid funding structures before and after the implementation of the Affordable Care Act (ACA) on health care access for Latinos in New York (Medicaid expansion), Florida (Medicaid non‐expansion), and Puerto Rico (Medicaid block grant).Data SourcesPooled state‐level data for New York, Florida, and Puerto Rico from the 2011–2019 Behavioral Risk Factor Surveillance System and data from the 2011–2019 American Community Survey and Puerto Rico Community Survey.Study DesignCross‐sectional study using probit with predicted margins to separately compare four health care access measures among Latinos in New York, Florida, and Puerto Rico (having health insurance coverage, having a personal doctor, delayed care due to cost, and having a routine checkup). We also used difference‐in‐differences to measure the probability percent change of having any health insurance and any public health insurance before (2011–2013) and after (2014–2019) the ACA implementation among citizen Latinos in low‐income households.Data CollectionThe sample consisted of Latinos aged 18–64 residing in New York, Florida, and Puerto Rico from 2011 to 2019.Principal FindingsLatinos in Florida had the lowest probability of having health care access across all four measures and all time periods compared with those in New York and Puerto Rico. While Latinos in Puerto Rico had greater overall health care access compared with Latinos in both states, health care access in Puerto Rico did not change over time. Among citizen Latinos in low‐income households, New York had the greatest post‐ACA probability of having any health insurance and any public health insurance, with a growing disparity with Puerto Rico (9.7% any [1.6 SE], 5.2% public [1.8 SE]).ConclusionsLimited Medicaid eligibility (non‐expansion of Florida's Medicaid program) and capped Medicaid funds (Puerto Rico's Medicaid block grant) contributed to reduced health care access over time, particularly for citizen Latinos in low‐income households.
Transcriptome analysis demonstrating the therapeutic effect of Tenodera angustipennis (Mantidis Ootheca) extracts on radiation‐induced gonadal toxicity in mouse testis
Authors: Kim Chul , Kim Joong Sun , Lee Hae June , Seong Boseok , Seo Seung‐won , Son Hyojung , Jeon Ji‐Hyeon , Shin Younhee 
Published: July 2022

AbstractMantidis Ootheca (MO) is the egg case of the praying mantis. MO has been used in Oriental and Chinese traditional medicine in a steamed form and is known for enhancing male fertility since ancient times. Here, we used total RNA sequencing to reveal the genome‐wide differential expression profiles of mice subjected to irradiation and Tenodera angustipennis MO extract treatment to understand the therapeutic effect of MO extract on radiation‐induced gonadal toxicity in mice. Approximately 225 genes exhibited differential expression patterns, among which 24 showed a reversal of expression pattern in response to irradiation and MO extract treatment. Most of these genes are associated with spermatogenesis and could be considered as candidates for further experimental studies. Considering that there is no approved radio‐protective drug for treating radiation‐induced damage to testicles, we would like to demonstrate the therapeutic potential of the use of MO extract as a traditional medicinal practice that can serve as a one of tool for the mitigation and treatment of gonadal toxicity.
A comparative study of in vitro gastrointestinal digestion of three strategic edible oils
Authors: Chabni Assamae , Bañares Celia , Reglero Guillermo , Torres Carlos F. 
Published: July 2022

AbstractThree strategic edible oils, that is, olive oil, microalgae oil, and shea butter, with a significantly different composition of fatty acids (FA), have been studied in a static in vitro digestion model to evaluate the rate of hydrolysis, bioaccessibility, and micellar phases formed in the process. Lipid composition of each phase and how the lipids are distributed in the different phases have been obtained using this in vitro digestion model. We demonstrate that the composition in FA and the physical properties of the oil are the key factors determining the distribution of lipids in the different phases. The fastest rate of hydrolysis was observed for olive oil and the highest triacylglycerol conversion was attained for shea butter. In contrast, the most abundant precipitate phase was obtained for shea butter, which also produces the highest co‐crystallization of cholesterol among the three edible oils studied. This study reveals that digestibility of edible oils is directly related with the initial rate of hydrolysis.
Assessing the affordability of nutrient‐adequate diets
Authors: Schneider Kate R. , Christiaensen Luc , Webb Patrick , Masters William A. 
Published: July 2022

AbstractThe cost and affordability of least‐cost healthy diets by time and place are increasingly used as a proxy for access to nutrient‐adequate diets. Recent work has focused on the nutrient requirements of individuals, although most food and antipoverty programs target whole households. This raises the question of how the cost of a nutrient‐adequate diet can be measured for an entire household. This study identifies upper and lower bounds on the feasibility, cost, and affordability of meeting all household members' nutrient requirements using 2013–2017 survey data from Malawi. Findings show only a minority of households can afford the nutrient‐adequate diet at either bound, with 20% of households able to afford the (upper bound) shared diets and 38% the individualized (lower bound) diets. Individualized diets are more frequently feasible with locally available foods (90% vs. 60% of the time) and exhibit more moderate seasonal fluctuation. To meet all members' needs, a shared diet requires a more nutrient‐dense combination of foods that is more costly and exhibits more seasonality in diet cost than any one food group or the individualized diets. The findings further help adjudicate the extent to which nutritional behavioral change programs versus broader agricultural and food policies can be relied upon to improve individual access to healthy diets.
ICIRAS: Research and reconciliation with indigenous peoples in rural health journals
Authors: Lock (Ngiyampaa) Mark J. , McMillan (Wiradjuri) Faye , Warne (Oglala Lakota) Donald , Bennett (Gamilaraay) Bindi , Kidd (Ngāpuhi) Jacquie , Williams (Bkejwanong) Naomi , Martire Jodie Lea , Worley Paul , Hutten‐Czapski Peter , Saurman Emily , Matthews (Quandamooka) Veronica , Walke (Bundjalung) Emma , Edwards (Worimi) Dave , Owen (Nurrunga and Ngarrendjeri) Julie , Browne Jennifer , Roberts Russell 
Published: July 2022

AbstractAimWe aim to promote discussion about an Indigenous Cultural Identity of Research Authors Standard (ICIRAS) for academic journal publications.ContextThis is based on a gap in research publishing practice where Indigenous peoples' identity is not systematically and rigorously flagged in rural health research publications. There are widespread reforms, in different research areas, to counter the reputation of scientific research as a vehicle of racism and discrimination against the world's Indigenous peoples. Reflecting on these broader movements, the editorial teams of three rural health journals—the Australian Journal of Rural Health, the Canadian Journal of Rural Medicine, and Rural and Remote Health—recognised that Indigenous peoples' identity could be embedded in authorship details.ApproachAn environmental scan (through a cultural safety lens where Indigenous cultural authority is respected, valued, and empowered) of literature was undertaken to detect the signs of inclusion of Indigenous peoples in research. This revealed many ways in which editorial boards of Journals could systematically improve their process so that there is ‘nothing about Indigenous people, without Indigenous people’ in rural health research publications.ConclusionImproving the health and wellbeing of Indigenous peoples worldwide requires high quality research evidence. The philosophy of cultural safety supports the purposeful positioning of Indigenous peoples within the kaleidoscope of cultural knowledges as identified contributors and authors of research evidence. The ICIRAS is a call‐to‐action for research journals and institutions to rigorously improve publication governance that signals “Editing with IndigenUs and for IndigenUs”.
Early evaluation of a next‐generation surgical system in robot‐assisted total laparoscopic hysterectomy: A prospective clinical cohort study
Authors: Borse Mahindra , Godbole Girish , Kelkar Dhananjay , Bahulikar Madhavi , Dinneen Eoin , Slack Mark 
Published: July 2022

AbstractIntroductionThis study aimed to demonstrate the safe and effective use of the Versius surgical system (CMR Surgical, Cambridge, UK) in robot‐assisted total laparoscopic hysterectomy. This surgical robot was developed iteratively with input from surgeons to improve surgical outcomes and end‐user experience. We report data from the gynecology cohort of an early clinical trial designed in broad alignment with IDEAL‐D (Idea, Development, Exploration, Assessment, Long‐term follow‐up – Devices) stage 2b (Exploration).Material and methodsThe study is registered in the Indian clinical trials register (CTRI/2019/02/017872). Adult women requiring total hysterectomy who provided informed consent and met the eligibility criteria underwent procedures at one of three hospitals in India. Five surgeons performed robot‐assisted total laparoscopic hysterectomies using the device from March 2019 to September 2020. The primary endpoint was rate of unplanned conversion to conventional laparoscopic or open surgery. Adverse events were adjudicated by an independent clinical events committee using endoscope video recordings and clinical notes.ResultsIn total, 144 women underwent surgery (median age: 44 years [range: 28–78]; median body mass index 25.8 kg/m2 [range: 14.3–47.8]). The rate of unplanned conversion to conventional laparoscopy was 2/144 (1.4%); neither conversion was device related. No surgery was converted to open. In total, 13 adverse events occurred among seven (4.9%) patients, comprising seven serious adverse events and six adverse events. One serious adverse event was deemed device‐related. Two patients were readmitted to hospital within 30 days; both made a full recovery. No patients died within 90 days of surgery.ConclusionsThe device provides a safe and effective option for total laparoscopic hysterectomy; these findings support its continued implementation in larger patient cohorts and expansion in other major minimal access indications.
Proton pump inhibitors for infants in three Scandinavian countries increased from 2007 to 2020 despite international recommendations
Authors: Lyamouri Miriam , Mårild Karl , Nielsen Rasmus Gaardskær , Størdal Ketil 
Published: July 2022

AbstractAimThere is weak evidence that proton pump inhibitors (PPIs) alleviate non‐specific complaints often attributed to gastroesophageal reflux in infancy and international guidelines do not recommend their use. We studied PPIs dispensed for infants in three Nordic countries.MethodsThis was an observational population‐based study of infants living in Norway, Sweden and Denmark in 2007–2020. We used nationwide pharmaceutical registers to study dispensed PPIs. The data provided a total of 3.3 million observed years on about 240 000 annual births.ResultsThe overall use of PPIs in infancy showed a marked increase in all three countries from 2007 to 2020. In 2020, PPI dispensing was 46.4, 23.4 and 18.9 per 1000 per year in infants aged 0–11 months in Denmark, Norway and Sweden. These were increases of 357%, 585% and 556% respectively. Although the rate was highest in Denmark, it had decreased by 42% in the last 3 years of the study.ConclusionDespite international recommendations against routine PPI prescribing in infancy, dispensed PPIs increased more than fourfold on average in three Nordic countries from 2007 to 2020. The reason for this notable increase could not be established from the data, but the large variations over time, and between the countries, probably indicated unwarranted use.
Translocation Detection from Hi-C Data via Scan Statistics
Authors: Cheng Anthony , Mao Disheng , Zhang Yuping , Glaz Joseph , Ouyang Zhengqing 
Published: July 2022

Abstract
Recent Hi-C technology enables more comprehensive chromosomal conformation research, including the detection of structural variations, especially translocations. In this paper, we formulate the interchromosomal translocation detection as a problem of scan clustering in a spatial point process. We then develop TranScan, a new translocation detection method through scan statistics with the control of false discovery. The simulation shows that TranScan is more powerful than an existing sophisticated scan clustering method, especially under strong signal situations. Evaluation of TranScan against current translocation detection methods on realistic breakpoint simulations generated from real data suggests better discriminative power under the receiver-operating characteristic curve. Power analysis also highlights TranScan's consistent outperformance when sequencing depth and heterozygosity rate is varied. Comparatively, Type I error rate is lowest when evaluated using a karyotypically normal cell line. Both the simulation and real data analysis indicate that TranScan has great potentials in interchromosomal translocation detection using Hi-C data.
Evaluation of fluid absorption during flexible ureteroscopy in an in vivo porcine model
Authors: Kottooran Christina , Twum‐Ampofo Jeffrey , Lee Jason , Saunders Jennifer , Franco Marle , Budrewicz Jay , Eisner Brian H. 
Published: July 2022

ObjectiveTo evaluate the relationship between renal pelvis pressure and fluid absorption during ureteroscopy (URS) in a live porcine model.Materials and MethodsFlexible URS (fURS) was performed in anaesthetised female Yorkshire pigs. Prior to performing fURS, a 0.3556‐mm (0.014″) pressure‐sensing guidewire (Comet™, Boston Scientific) was placed to monitor renal pelvis pressure. A simulated fURS procedure was then performed for 1 h. Infusion of irrigation fluid (5% ethanol in saline) at target renal pelvis pressures (37–150 mmHg) was maintained for 1 h using a pressure bag and real‐time feedback from the pressure‐sensing guidewire. Venous blood was sampled every 10 min. The volume of irrigation fluid absorbed was estimated with established equations.ResultsA URS procedure was performed in vivo in 18 porcine kidneys and the volume of irrigation fluid absorbed during the 1 h URS was calculated. The mean (SD) volume of irrigation fluid absorbed after 1 h of simulated URS was 7.6 (5.7), 10.8 (7.1), 26.0 (15.8), and 56.8 (22.3) mL at renal pelvis pressures of 37, 55, 75, and 150 mmHg, respectively. Compared with URS with renal pelvis pressure of 37 mmHg, the volume of fluid absorption was significantly greater at renal pelvis pressures of 75 and 150 mmHg (P = 0.026 and P = 0.047, respectively). In addition, compared with URS with renal pelvis pressure of 37 mmHg, the rate of absorption was significantly greater at renal pelvis pressures of 75 and 150 mmHg (both P < 0.001).ConclusionIn this study of an in vivo porcine model of URS, increasing renal pelvis pressures during URS were associated with increases in irrigation fluid absorption and increases in the rate of fluid absorption.
The Icatibant Outcome Survey: 10 years of experience with icatibant for patients with hereditary angioedema
Authors: Maurer Marcus , Aberer Werner , Caballero Teresa , Bouillet Laurence , Grumach Anete S. , Botha Jaco , Andresen Irmgard , Longhurst Hilary J. ,   for the IOS Study Group
Published: July 2022

AbstractIn patients with hereditary angioedema (HAE), bradykinin causes swelling episodes by activating bradykinin B2 receptors. Icatibant, a selective bradykinin B2 receptor antagonist, is approved for on‐demand treatment of HAE attacks. The Icatibant Outcome Survey (IOS; NCT01034969) is an ongoing observational registry initiated in 2009 to monitor the effectiveness/safety of icatibant in routine clinical practice. As of March 2019, 549 patients with HAE type 1 or 2 from the IOS registry had been treated of 5995 total attacks. This article reviews data published from IOS over time which have demonstrated that the effectiveness of icatibant in a real‐world setting is comparable to efficacy in clinical trials; one dose is effective for the majority of attacks; early treatment (facilitated by self‐administration) leads to faster resolution and shorter attack duration; effectiveness/safety of icatibant has been shown across a broad range of patient subgroups, including children/adolescents and patients with HAE with normal C1 inhibitor levels; and tolerability has been demonstrated in patients aged ≥65 years. Additionally, this review highlights how IOS data have provided valuable insights into patients' diagnostic journeys and treatment behaviours across individual countries. Such findings have helped to inform clinical strategies and guidelines to optimise HAE management and limit disease burden. This research was sponsored by Takeda Development Center Americas, Inc. Takeda Development Center Americas, Inc., provided funding to Excel Medical Affairs for support in writing and editing this manuscript.