bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lymphadenopathy: Algorithm for the Diagnosis and Management
Authors: Коваль Т.И. , Изюмская Е.М. , Марченко Е.Г. , Прийменко Н.О. , Котелевская Т.М. , Боднар В.А. 
Published: February 2022

Встатье подробно охарактеризован синдром лимфаденопатии, представлены терминология, причины, патофизиологические механизмы, классификация, варианты поражения лимфатических узлов при инфекционной и неинфекционной патологии. Приведен алгоритм диагностического поиска, который состоит из 3 этапов: оценки клинико-анамнестических данных, проведения рутинных лабораторных и инструментальных исследований и выполнения при необходимости дополнительных исследований согласно клинической ситуации. Предоставлены подходы к тактике ведения пациентов с неуточненной лимфаденопатией. Учитывая мультидисциплинарность синдрома лимфаденопатии, успешное решение проблемы дифференциальной диагностики этого состояния зависит от конструктивного взаимодействия многих специалистов (семейных врачей, инфекционистов, онкологов, гематологов, ревматологов, морфологов), их осведомленности о заболеваниях, проявляющихся увеличением лимфатических узлов, и понимания тактики ведения пациентов.
The article is focused on the syndrome of lymphadenopathy, presents the terminology, causes, pathophysiological mechanisms, classification, and variants of damage to lymph nodes in cases of infectious and non-infectious pathologies. The algorithm of diagnostic search is presented, which consists of 3 steps: assessment of clinical and anamnestic data, routine laboratory and instrumental examination results, and, if necessary, additional evaluations according to the clinical situation. Approaches to patient’s management tactics with unspecified lymphadenopathy are provided. Considering the multidisciplinary of lymphadenopathy syndrome, a successful solution to the problem of differential diagnosis of this condition depends on the constructive interaction of many specialists (family doctors, infectious disease specialists, oncologists, hematologists, rheumatologists, morphologists), their awareness of diseases manifested by an increase in lymph nodes, and an understanding of patient`s management tactics.
Changes in the Cytogenetic Parameters of Buccal Epithelium Cells in Patients with Oral Lichen Planus in the Dynamics of Treatment
Authors: Алескерова Ф.А. 
Published: February 2022

В статье представлены данные об изменениях в клетках буккального эпителия (БЭ) у 15 пациентов с эрозивно-язвенной формой красного плоского лишая слизистой оболочки полости рта. Красный плоский лишай слизистой оболочки полости рта – это хроническое воспалительное неинфекционное заболевание, которое вызывает поражение тканей слизистой оболочки полости рта, языка или десен. Исследования изменений цитогенетических нарушений клеток буккального эпителия у пациентов с красным плоским лишаем слизистой оболочки полости рта единичны, и не представлены данные по изменению ядерных аномалий в динамике лечения. Проведенные исследования показывают, что лечение пациентов с красным плоским лишаем слизистой оболочки полости рта способствует в незначительной степени снижению клеток с генетическими нарушениями и повышению клеток с апоптозной активностью, а также избавлению от данных аберрантных клеток.
The article presents data on changes in the cells of the buccal epithelium in 15 patients with erosive – ulcerative form of oral lichen planus. Lichen planus of the oral mucosa is a chronic, inflammatory, non-infectious disease that damages the tissues of the oral mucosa of the tongue or gums. Studies of changes in cytogenetic disorders of buccal epithelium (EB) cells in patients with oral lichen planus are rare and data on changes in nuclear anomalies in the dynamics of treatment are not presented. The conducted research shows that the treatment of patients with oral lichen planus contributes to a small extent to a decrease in cells with genetic disorders and an increase in cells with apoptotic activity and helps to get rid of these aberrant cells.
Features of the Course of Pregnancy and Childbirth in Women with COVID-19 Infection in the First and Second Trimesters of Pregnancy
Authors: Юркевич Т.Ю. , Прибушеня О.В. , Гасич Е.Л. , Ринкевич Е.П. 
Published: February 2022

Перенесенная беременными инфекция COVID-19 в первом и втором триместрах беременности может оказать неблагоприятное воздействие на течение беременности и родов. Мы исследовали 109 беременных женщин с лабораторно подтвержденной инфекцией COVID-19 методом ПЦР в сроке гестации 4 недели – 21 неделя 6 дней. Наиболее частыми симптомами заболевания у этих беременных явились повышение температуры (у 82 (75,2%) пациентов) и аносмия (у 73 (66,9%)), которая часто сочеталась с агевзией. Редкими проявлениями были миалгия (у 12 (11%) пациентов), одышка (у 7 (6,4%)), ринорея (у 7 (6,4%)), чувство тяжести в груди (у 4 (3,7%)). При проведении комбинированного скрининга первого триместра на выявление групп высокого риска по хромосомным заболеваниям мы установили снижение показателя free β-hCG до 0,94 (0,64–1,30) МоМ у перенесших COVID-19 в первом триместре. Частота поражения мочевыводящей системы плода составила 7 (6,4%) случаев, из них врожденный порок развития (ВПР) выявлен у 4 (3,7%) пациентов. Все роды в группе исследования были срочными. Средний срок родоразрешения составил 38,6 (37–42) недели. Роды в 8% случаев осложнились развившимся дистресс-синдромом плода, что потребовало их завершения экстренным кесаревым сечением.
Infection carried by pregnant women with COVID-19 in the first and second trimesters of pregnancy can have an adverse effect on the formation of obstetric complications associated with the pathology of implantation. We examined 109 pregnant women with laboratory-confirmed COVID-19 infection by PCR at 4 weeks gestation – 21 weeks 6 days. The most frequent symptoms of the disease in these pregnant women were fever in 82 (75.2%) and anosmia, which was often combined with ageusia in 73 (66.9%). Rare manifestations were myalgia in 12 (11%) pregnant women, shortness of breath in 7 (6.4%), rhinorrhea in 7 (6.4%), complaints of a feeling of heaviness in the chest in 4 (3.7%). We established a decrease in the free β-hCG index to 0.94 (0.64–1.30) MoM. The incidence of fetal urinary tract damage was 7 (6.4%), of which 4 (3.7%) had congenital malformations. All childbirth was urgent. The average delivery time was 38.6 (37–42) weeks. Labor in 8% was complicated by the developed distress syndrome of the fetus in labor, which required the completion of labor by emergency caesarean section.
Cocaine as a Risk Factor for Heart and Vascular Disease. Part 1
Authors: Зыбалова Т.С. , Достанко Н.Ю. , Ягур В.Е. , Борис А.М. 
Published: February 2022

В обзоре приведены основные свойства, формы, метаболизм, фармакокинетика кокаина, возможные результаты его взаимодействия с другими веществами и лекарственными средствами, различные аспекты влияния кокаина на сердечно-сосудистую систему. Подробно рассмотрены механизмы действия кокаина, лежащие в основе развития основных широко распространенных патологических процессов в сердце и сосудах. Проанализированы данные большого числа опубликованных исследований, посвященных влиянию кокаина на развитие различных нарушений проводимости и ритма сердца, артериальной гипертензии, эндотелиальной дисфункции, расслоение крупных артерий и аорты. Также обсуждены особенности действия кокаина в разных группах пациентов и в зависимости от длительности его употребления. Приведены рекомендации по диагностике и выбору терапии при ряде патологических состояний, связанных с употреблением кокаина. Особое внимание уделено спорным вопросам лечения и влияния кокаина на сердце и сосуды, диагностическим возможностям различных методов исследования.
The review presents the main properties, forms, metabolism, pharmacokinetics of cocaine, possible results of its interaction with other substances and medicines, various aspects of cocaine effect on the cardiovascular system. The mechanisms of cocaine action underlying the development of the main widespread pathological processes in the heart and blood vessels, are considered in detail. The data of a large number of published studies on the cocaine influence on the development of various disorders of conduction and heart rhythm, arterial hypertension, endothelial dysfunction, and dissection of large arteries and aorta are analyzed. The particulars of action with the duration of cocaine use as well as in different groups of patients are discussed. Recommendations are given for the diagnostics and choice of therapy for a number of pathological conditions associated with cocaine use. Particular attention is paid to controversial issues of treatment and effect of cocaine on the heart and blood vessels, the diagnostic capabilities of various diagnostic methods.
Optimization of Bifurcation Treatment Tactics Coronary Artery Stenosis in Patients with Ischemic Heart Disease Using Optical Coherent Tomography. Case Report
Authors: Анваров Ж.О. , Махкамов Н.К. 
Published: February 2022

В данной статье на клиническом примере интервенционного лечения пациента с ишемической болезнью сердца описаны преимущества технологии оптической когерентной томографии (ОКТ) при стентировании сложного бифуркационного стеноза коронарных артерий, который оценивался по критериям классификации DEFINITION. Коронарная ангиография является «золотым стандартом» визуализации поражений коронарных артерий. Однако эта техника ограничена двухмерным представлением силуэта просвета и не всегда дает точную информацию о результатах ангиопластики и стентирования коронарных артерий. ОКТ сегодня – это ключевой метод внутрикоронарной визуализации, который в состоянии преодолеть многие недостатки ангиографического метода.
In this article, the advantages of optical coherence tomography (OCT) for stenting complex bifurcation stenosis of the coronary arteries is described in clinical example of interventional treatment of coronary heart disease, which was evaluated according to the DEFINITION classification criteria. Coronary angiography is the "gold standard" of visualization of coronary artery lesions. However, this technique is limited to a two- dimensional representation of the silhouette of the lumen and does not always provide accurate information about the results of angioplasty and stenting of the coronary arteries. OCT today is a key method of intracoronary imaging, which is able to overcome many disadvantages of the angiographic method.
Sistem Informasi Manajemen Aset dan Inventaris menggunakan QR Code di Kantor Camat Petang
Authors: Setiawan I Kadek Subudi , Wijaya I Nyoman Yudi Anggara 
Published: February 2022

Abstract—Information and communication technology in this era it’s very rapid development. The impact of this information technology is very large felt in supporting the performance and activities ranging from schools, businesses and government agencies. Government agencies have used a lot of information systems that help the performance of these agencies to support the speed of the government process, but this information system has not been used as a whole in the government process especially in the sub-district office that still uses manual methods in recording inventory data owned by the agency. This research was made with the waterfall method that begins with the planning process of the system in which in this process a system of planning will be made related to the problems that exist in the camat petang office, then the modeling process where the system in the form of system design will be made, then the process is carried out implementation and testing of systems that have been made. Based on the problems and data obtained, an asset management information system and inventory were made using QR-Code, this system is useful for recording assets, providing information related to assets in a complete and fast way and providing convenience in bleaching items that are damaged or cannot be used anymore.

Keywords: simanis, information systems, management, assets, inventory, QR-Code
Implementasi Bimbingan dan Konseling Daring pada Madrasah Tsanawiyah di Jawa Timur
Authors: Akhmadi Agus , Supriyati Ninik 
Published: February 2022

[IMPLEMENTATION OF ONLINE GUIDANCE AND COUNSELING AT MADRASAH TSANAWIYAH IN EAST JAVA] Online guidance and counseling service is a service that is used during the pandemic. This study aims to describe the process and results of online counseling services in madrasas. The research method used is a survey with a descriptive approach. Research respondents were 383 students who received online guidance and counseling services at Madrasah Tsanawiyah. Questionnaires and interviews were used to collect the data. The instrument is uploaded in a google form, sent to the students through the guidance and counseling teachers. The questionnaire data were processed by descriptive statistics and analyzed through descriptive qualitative techniques. The results of this study indicate that online guidance and counseling services are carried out well. The online service process is fun and easy for students, the service is effective. There was an obstacle for several students due to the internet problem.
Factors Influencing The Growth and Development of Children with Stunting, Scoping Review
Authors: Dwijayanti Novia , Mufdlilah Mufdlilah 
Published: February 2022

Background: Data related to stunting rates known by country include Thailand (10.5%), Sri Lanka (27.3%), Maldives (20.3%), North Korea (27.9%), Myanmar (29.2%). ), Bhutan (33.6%), Nepal (35.8%), Bangladesh (36.1%), Timor Leste (50.2%), India (38.4%), and Indonesia (36.4% ). Referring to the results of the Basic Health Research (Riskesdas) conducted every 5 years, it is known that the percentage of stunting in Indonesia has decreased from 37.2% in 2013 to 30.8% in 2018. Growth and development are closely related to stunting are considered an important indicator of inequality in child health. This can be caused by several factors, both before and after giving birth in the developmental phase, including poor nutrition, household environment, and parents' education and economy.
Research Objectives: This study aims to systematically map the research carried out in this field and identify factors that influence stunting growth and development.
Methods: The method used is Prism Flowchart (Preferred Reporting Items For Systematic review and Meta-Analyses). It is used to describe the flow of the literature search. Article searches were conducted using 3 databases (PubMed, Wiley, and ProQuest). The inclusion criteria for articles are articles published in 2015-2020, in English and discuss the Factors Affecting the Growth and Development of Children with Stunting. The article search flow is described using the PRISMA Flowchart, while the article quality assessment is carried out using Hawker and CASP. The next stage is the preparation of data and reporting of results.
Result: Based on the critical appraisal results from 12 articles that have been selected through the cross-sectional method, 11 articles were obtained (A1, A2 A3, A4, A5, A6, A7, A8, A10, A11, A12) and 1 study cohort article (A9). Based on the quality of the articles that have undergone critical appraisal, it was found that several articles obtained grade B (A1, A2, A3, A4, A6, A7, A8, A9, A10, A11, A12) and 1 article received grade D (A5).
Conclusion: The findings from this scoping review are that the child's gender, child's age, mother's age, mother's education, mother's occupation, wealth, economy, nutritional status before and after giving birth, clean water sanitation, latrine management, hygiene, and environmental factors, have an effect on stunting which may hinder the growth and development of children in the future.
Role of Semantics in Figurative-Texture of Matthew Arnold’s Dover Beach
Authors: Yadav Meenakshi Sharma , Quadri Kahkasha Moin , Osman Mohammad 
Published: February 2022

Semantics process plays a key-role in learning the literal and contextual meanings of a poem’s figurative-texture (Bredin, 1992; Cuccio, et al., 2014; Depraetere 2019). Improper understanding of semantics mechanism and contextual theories may lead also the common and determined audiences to learn ambiguious message and meaning of a word (Leclercq, 2020; Satta, 2020) that has many possible meanings which create semantic ambiguities and conflicts (Hoffman, et al., 2013). However, a poem audience must know that how does the meaning of a word or phrase work and how can he and she remove confusion to comprehend the literal meanings in the figurative language contexts of a poem. The figuarive-texture of Arnold’s Dover Beach is fabricated within diversed figures of speeches uploaded in the text. The collage text image of figurative texture presents common words and phrases with the byzantine meanings and misinformation of the synonyms and antonyms lexical pragmatic interface to the readers. In support and singnifant solutions for the research gap, this article attempt defined and described creatively to the role of semantics in the figurative-texture of Matthew Arnold’s Dover Beach so that collective and determined audiences can comprehend the poem creatically based on qualitative description research methodology.
Understanding, Oral Hygiene Practices, Behaviors and Myths to deal with Toothache in Rural Areas
Authors: Sarang Suresh Hotchandani  , Priya Rani Harjani  , Suneel Kumar  Punjabi  , Mowaffaq Abdullmomen  Al Absi  , Hafiz Mahmood Azam  , Ahmed Aswad 
Published: February 2022

BACKGROUND & OBJECTIVE: In Pakistan, there is lack of awareness to maintain oral hygiene and cleaning of oral structures. The current study aims to unveil homemade remedies and self-care methods followed by a majority of the rural population to cure dental pain in Sindh, Pakistan.
METHODOLOGY: This cross-sectional descriptive study was conducted at dental OPD of the Secondary Health Care Facility of Sindh, Pakistan, by following a random sample selection approach. Patients from both genders representing oro-dental problems of ages ≥ 5 year were included in the study. Patient’s clinical and demographic data was collected, and further descriptive data analysis was done by using Microsoft Excel 2016.
RESULTS: A total of 1627 patients fulfilled the inclusion criteria of the study. The highest number of cases (73.81%) were belonging to the age group 15-49 years, affirming that adults are at greater risk of developing toothache and dental pain. Surprisingly, about 78.97% patients had never visited any physician for seeking the clinical services. Similarly, 37.18 % of patients did not use any cleaning substance while 22.12 % patients preferred miswak for cleaning of their teeth. Only 2.95 % of patients visited dentists for proper care.
CONCLUSION: Current research report concludes that from all the confirmed toothache cases, 22.13 % of patients sought care from general physicians in parallel with 22.34 % patients were preferring religious spells to manage their dental pain, which further multiplied the disease rate. However, general physicians at primary healthcare settings have limited knowledge and training in managing dental pain.
THE Missed dose error among nurses working at tertiary care Hospitals, Karachi
Authors: Raja  , Badil  , Pawan Kumar  , Sana Rehman  , Gulsher  
Published: February 2022

BACKGROUND & OBJECTIVE: Medication administration error (MAE) has been recognized as a serious health related issue that can lead to surge mortality and morbidity. In addition, it may rise hospitalization that, will increase the ratio of the patient. This study was accomplished to determine the missed dose error among nurses working at tertiary care hospitals in Karachi.
METHODOLOGY: This analytical cross-sectional study was accomplished at Dr. Ruth K.M. Pfau Civil Hospital and Dow University Hospital, Karachi, for the period of six months from February to July 2018. The calculated sample was 204 nurses of both genders. Nurses having one year of working experience and licensed with Pakistan Nursing Council had been invited for the study. The participants were approached by a non-probability convenient consecutive sampling method. The adopted and validated questionnaire was utilized to gather the data. The data was entered and analyzed by using SPSS version 21.0.
RESULTS: Out of 204 subjects, 106 (52%) were male. With respect to age, 168 (82.3%) of respondents had age below 35 years. The percentage of missed medication doses was reported to be 12.3%. In this study, nurses to patients ratio, and timing of medication administration were found statistically significant with missed dose errors p-value≤0.05.
CONCLUSION: The study finding showed a small frequency of missed dose errors among nurses working in tertiary care public sector hospitals, Karachi. The majority of missed doses were recorded in the morning shift, and nurses who had more patients ratio.
The Environments of CO Cores and Star Formation in the Dwarf Irregular Galaxy WLM
Authors: Archer Haylee N. , Hunter Deidre A. , Elmegreen Bruce G. , Cigan Phil , Jansen Rolf A. , Windhorst Rogier A. , Hunt Leslie K. , Rubio Monica 
Published: February 2022

Abstract
The low metallicities of dwarf irregular galaxies (dIrr) greatly influence the formation and structure of molecular clouds. These clouds, which consist primarily of H2, are typically traced by CO, but low-metallicity galaxies are found to have little CO despite ongoing star formation. In order to probe the conditions necessary for CO core formation in dwarf galaxies, we have used the catalog of Rubio et al. for CO cores in WLM, a Local Group dwarf with an oxygen abundance that is 13% of solar. Here we aim to characterize the galactic environments in which these 57 CO cores formed. We grouped the cores together based on proximity to each other and strong FUV emission, examining properties of the star-forming region enveloping the cores and the surrounding environment where the cores formed. We find that high H i surface density does not necessarily correspond to higher total CO mass, but regions with higher CO mass have higher H i surface densities. We also find the cores in star-forming regions spanning a wide range of ages show no correlation between age and CO core mass, suggesting that the small size of the cores is not due to fragmentation of the clouds with age. The presence of CO cores in a variety of different local environments, along with the similar properties between star-forming regions with and without CO cores, leads us to conclude that there are no obvious environmental characteristics that drive the formation of these CO cores.