bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distribution of b-value in the central and southern Ryukyu: is the low b-value in the rift-axis of the Okinawa Trough accurate?
Authors: Nakamura Mamoru 
Published: December 2022

AbstractHere, I investigated whether the b-value in the rift-axis of the Okinawa Trough, a back-arc basin, is low. The cause of the low b-value in the rift-axis of the Okinawa Trough had previously been interpreted as increased stress by dyke intrusion. However, the previous study ignored the spatial variations in magnitude completeness in the Okinawa Trough. In addition, for the M4-class earthquakes that occurred in the Okinawa Trough, the values of displacement magnitudes and velocity magnitudes determined by the Japan Meteorological Agency (JMA) for the same events did not match. The previous study did not correct for these effects. Thus, I conducted these corrections and examined the spatial variation of b-values in the Okinawa Trough and the Ryukyu arc. The magnitude completeness was calculated using goodness-of-fit methods and the b-value was calculated using the maximum likelihood method. The JMA earthquake catalog from 2001 to 2019 was used for the analysis. After the corrections, the b-values around the rift-axis of the central and southern Okinawa Trough (0.90–0.92) were almost the same as those for the Ryukyu arc (0.83–0.84). Magnitude completeness in the Okinawa Trough varied spatially and was particularly large in the earthquake swarm area in the rift-axis of the Okinawa Trough. The steady-state magnitude completeness was 2.0 in the earthquake swarm area in the rift-axis of the Okinawa Trough. However, the magnitude completeness increased to 3.5 or higher only during the several days of occurrence of the earthquake swarms. This was caused by the short-term decrease in the ability to detect earthquakes when an earthquake swarm occurred. The finding that the b-values do not differ between the rift-axis of the Okinawa Trough and the Ryukyu arc indicates that stress concentration in the rift-axis of the Okinawa Trough is not a strong influence on the b-values. Alternatively, this might indicate that in the rift-axis of the Okinawa Trough, the distribution of low and high b-value regions was not detectable due to the insufficient accuracy of hypocenter determination.
Graphical Abstract
A robust principal component analysis-based approach for detection of a stator inter-turn fault in induction motors
Authors: Namdar Ali 
Published: December 2022

AbstractHealth condition monitoring of induction motors is important because of their vital role and wide us in a variety of industries. A stator inter-turn fault (SITF) is considered to be the most common electrical failure according to statistical studies. In this paper, an algorithm for the detection of an SITF is presented. It is based on one of the blind source separation techniques called principal component analysis (PCA). The proposed algorithm uses PCA to discriminate between the faulty components of motor current signatures and motor voltage signatures from other components. The standard deviation of one of the decomposed vectors is used as a statistical SITF criterion. The proposed criterion is robust to non-fault conditions including voltage quality problems and large mechanical load changes as well as harmonic contaminants in the voltage supply. In addition, with a straightforward and low computational burden in the fault detection process, the proposed method is computationally efficient. To evaluate the performance of the proposed method, large numbers of practical and simulation scenarios are considered, and the results confirm the good performance, high degree of accuracy, and good convergence speed of the proposed method.
Translation and cultural adaptation of the pectus excavatum evaluation questionnaire to Spanish and Catalan
Authors: de Haro Jorge Irene , Tarrado Xavier , Albert Cazalla Asteria , García-Smith Natalie , Fernàndez-Candial Alba , Salcedo-Gil Carlos 
Published: December 2022

Abstract
Purpose
Pectus excavatum (PE) is the most common congenital chest wall deformity. It can have a negative effect in exercise tolerance. However, cosmetic features are the most frequent concerns in these patients. The PE evaluation questionnaire (PEEQ) is a patient reported outcome (PRO) tool to measure the physical and psychosocial quality-of-life changes after surgical repair of PE. No specific tool has been developed in our languages to evaluate PRO in PE patients. Our aim is to translate and culturally adapt the PEEQ to Spanish and Catalan.

Methods
Guidelines for translation of PRO were followed. The PEEQ, consisting of 34 items, was translated from English to Spanish and to Catalan. Three forward translations and one back translation were performed for each language. Cognitive debriefing interviews were developed.

Results
The reconciliation of the forward translations revealed a 14.7% of inconsistencies for each language. The Spanish back translation showed a 64.7% of disagreement with the source, the Catalan 58.8%. Changes in each reconciled version were made to amend the diverting items. Cognitive debriefing: Catalan version: 15 participants, 10 males, 5 patients had been operated. 12 patients showed difficulties for understanding 4 of the items. Spanish version: 17 participants, 11 males, 5 had been operated. 13 patients showed difficulties for understanding 4 of the items. We made modifications of the problematic items, in order to make them easier to understand for our patients. We tested the last version in a new group of patients. Catalan: 7 patients, 5 males. One patient showed difficulties for understanding item 11, so we added a further clarification of this item. Spanish: 7 patients, all males. There were any difficulties for understanding.

Conclusion
After a thorough process of translation and cultural adaptation, we reached a Catalan and a Spanish version of PEEQ. This work constitutes the first step to reach a specific PE PRO tool in our languages. However, it needs to be validated, with a higher number of patients, before being widely used in a clinical setting.
Protective effect of curcumin on the kidney of diclofenac sodium-challenged mice: apoptotic, redox potential and histopathological outcomes
Authors: Ragab Sohair M. M. , Abd-Elkareem Mahmoud , Abou Khalil Nasser S. , Atia Mona M. 
Published: December 2022

Abstract
Background
The renal burden imposed by diclofenac sodium (DS) remedy is a significant concern and limits the extension in its clinical application. Curcumin (Cur) can be used as a promising natural phytochemical in rescuing chemotherapy-associated renal dysfunction owing to its redox stabilizing and cytoprotective nature. Thus, the current experiment aims to highlight the possible ameliorative impact of Cur on DS-induced renal damage and its mediating mechanisms in adult male mice.

Methods
A total number of eighteen healthy adult mice of the male sex were classified into 3 groups for 21 days. The first group served as a control, whereas the second one received DS at 10 mg/kg body weight by intraperitoneal route of administration daily during the last 14 days of the experiment. The third group was supplemented with Cur at 100 mg/kg body weight during the entire duration of the intervention in conjunction with the DS burden. At the end of the experimental protocol, kidney functions, redox parameters, histopathological investigation and TUNEL assay were performed.

Results
Cur succeeded in restoring the typical histomorphometric features and reducing the apoptosis in the kidney. The redox disturbances in the kidney of DS-challenged mice rebalanced were manifested by normalizing the level of renal reduced glutathione and immunostaining of glutathione reductase and superoxide dismutase 2. No marked alteration in plasma urea level in the DS group could be noticed compared to the control. Nevertheless, an obvious reduction in plasma urea level was observed in the DS+Cur group relative to the control and DS groups. The comparison between all experimental groups revealed the absence of significant difference in plasma creatinine and renal lipid peroxide levels.

Conclusions
Cur might exert its renoprotective action through its cytoprotective, anti-apoptotic and antioxidant characteristics. The findings of this study shed light on using natural phytochemicals to alleviate the adverse influences of chemotherapies.
Plant-based pecan nut cake beverage enrichment of phytochemicals and antioxidant properties using multi-stage block freeze concentration
Authors: Maciel Laércio Galvão , Teixeira Gerson Lopes 
Published: December 2022

AbstractPecan nut (Carya illinoinensis) processing to obtain oil generates circa 37% of press cake, which is currently underutilized and primarily employed as animal feed. Due to its nutritional- and bioactive-rich composition, pecan nut cake (PNC) can be used as raw material for plant-based beverages, whose properties may be enhanced using a non-thermal technology based on block freeze concentration (BFC). The effect of five-stage BFC on total solids content (TSC), pH, color parameters, retention of phytochemicals, and the antioxidant activity (AA) of a pecan nut cake beverage (PNB) was assessed in this work. BFC afforded 98% (w/w) solids retention after three stages and 85% efficiency after four stages. The process also provided a 254% concentration factor in stage 5. In the last step, approximately a 64% increase in TSC and a slight decrease (7.3%) in pH compared to the control PNB was observed. In addition, total phenolic compounds, condensed tannins, total flavonols, and AA were significantly (P < 0.05) improved after the BFC, resulting in a 2.6-10.2- and 1.9-5.8-fold increase in phytochemicals and antioxidants, respectively. On the other hand, BFC caused the darkening of concentrates due to TSC and bioactive compounds retention. The processing strategy evaluated herein indicated a great potential of PNC as a raw material for obtaining high-quality ingredients for the food industry, which may reduce agro-industrial waste production and add value to a coproduct rich in nutrients and biocompounds with potential biological activity.
Graphical Abstract
Gene polymorphisms of interleukin 10 (− 819 C/T and − 1082 G/A) in women with ovarian cancer
Authors: Almolakab Zainab M. , El-Nesr Khalid A. , Mohamad Ehab H. , Elkaffas Rasha , Nabil Ahmed 
Published: December 2022

Abstract
Background
Ovarian cancer (OC) is the leading cause of death associated with gynecologic cancer. IL-10 plays an important role in tumorigenesis. We investigated IL-10 gene polymorphisms in OC patients. The current case–control study screened forty-eight women with OC and forty-eight healthy women who did not have OC. The genotyping of SNPs (− 1082 G > A; rs1800896 and − 819 C > T; rs1800871) of the IL-10 gene was done by tetra primers sequence-specific primer polymerase chain reaction (SSP-PCR) technique. The plasma levels of IL-10 were measured using an enzyme-linked immunosorbent assay (ELISA).

Results
For IL-10 (− 1082 G/A) polymorphism, the G (wild allele) was significantly associated with increasing the risk of OC (OR = 2.054 with CI = 1.154–3.657; P < 0.05), while the A (variant allele) and AA genotype was significantly associated with decreasing the risk of OC (OR = 0.487 with CI = 0.273–0.867; P < 0.05) and (OR = 0.15; 95% CI = 0.04–0.63; P < 0.05), respectively. For IL-10 (− 819C/T) polymorphisms, the T allele (variant allele) and (TT, CT genotypes) were significantly associated with increasing the risk of OC (OR = 2.800 with 95% CI = 1.577–5.037; P < 0.05), (OR = 18.33 with 95% CI = 3.46–97.20; P < 0.001), and (OR = 9.44 with 95% CI = 2.52–35.40; P < 0.001), respectively, while the C (wild allele) was significantly associated with decreasing the risk of OC (OR = 0.357 with 95% CI = 0.199–0.642; P < 0.05). The haplotype analysis for (− 1082 G > A and − 819 C > T shows the GT haplotype was significantly associated with increasing the risk of OC (OR = 50.09 with CI = 6.34–395.92; P < 0.001). OC was substantially correlated with IL-10 level (r = 0.457; p < 0.001). There is no linkage disequilibrium (LD) between IL 10 − 1082 G/A and IL 10 − 819 C/T (D′ = 0.1315, r2 = 0.016; P = NS). A statistically significant positive relationship existed between IL-10 and CA125 and ALT (P < 0.05). IL-10 and albumin showed a strong negative association (P < 0.05), whereas the correlation of IL10 plasma level with BUN, AST, T. Bil., TLC, PLT, Cr., and HB has not any significant value (P > 0.05).

Conclusions
Overall, this study supports an association of IL-10 (− 1082 G/A and − 819C/T) polymorphisms with the risk of ovarian cancer.
Efficacy of some washing solutions for removal of pesticide residues in lettuce
Authors: Balkan Tarık , Yılmaz Özlem 
Published: December 2022

Abstract
Background
When previous studies were examined, it was reported that a wide variety of pesticide residues were detected in lettuce (Bakırcı et al. in Food Chem 160:379–392, 2014; Balkan and Yılmaz in Food Chem 384:132516, 2022; Qin et al. in Food Res Int 72:161–167, 2015; Selim et al. in Res J Environ Sci 5:248–258, 2011). In addition, pesticide-contaminated lettuce poses a risk to consumers as it is a fresh food that is eaten raw. Therefore, pesticide removal processes must be applied before consumption. Some pesticide removal process, such as storage and heat treatment cannot be applied to lettuce because of unshelled, no long shelf life and consuming as fresh. Different practical methods are needed for the removal of pesticides process. The recommendations of suitable methods for cleaning salad materials in ready-to-eat sector, hotels, restaurants and homes are very important. It is important to reduce pesticide residues in vegetables and fruits that are consumed raw by washing them with non-toxic solutions. These approaches aim to protect public health. The study conducted in 2021 determined the effect of various washing treatments. For this purpose, before the washing trials, QuEChERS method was validated for determination of 7 pesticides in lettuce, by liquid chromatography–tandem mass spectrometry (LC–MS/MS). Lettuce plants were grown in the greenhouse for the study. Lettuces were brought to the laboratory 24 h after pesticides were applied in the greenhouse. The samples were kept in 2 L washing solution for pesticide analysis.

Results
The processing factor values of all washing applications were found below 1. This result shows that the residue level was reduced by washing solutions. Among the washing solution treatments, the rice vinegar washing solution was found to be most effective in reducing the pesticide residues which was due to the high degree in the pesticide degradation. Washing with filtered rice water also exhibited equivalent reduction capability similar to rice vinegar.

Conclusions
The effectiveness of washing solutions was different for boscalid, deltamethrin, fluopcolide, fluopyram, pyrimethanil, pyraclostrobin and sulfoxaflor. However, when the average removal of these pesticides was evaluated, the most effective solutions were rice vinegar, filtered rice water, carbonated water, NaCl + grape vinegar, hot tap water (40 °C), grape vinegar (6% acetic acid), grape vinegar + water, cold tap water (20 °C), lemon juice, baking soda water, grape vinegar (8% acetic acid), filtered mint water and grape vinegar (4% acetic acid), respectively. It was concluded that some of the solutions used in this study can significantly reduce exposure to pesticides for consumers.
A comprehensive review on invasomal carriers incorporating natural terpenes for augmented transdermal delivery
Authors: Kumar Bhumika , Pandey Mukesh , Aggarwal Rohan , Sahoo Pravat Kumar 
Published: December 2022

AbstractBackgroundTransdermal drug delivery is one of the most widely used drug administration routes, which offer several advantages over other routes of drug delivery. The apical layer of the skin called thestratum corneumis the most dominant obstacle in the transdermal drug delivery, which restricts the passage of drugs across the skin. Considerable strategies have been applied to enhance the rate of permeation across the epithelial cells; however, the most widely used strategy is the use of sorption boosters, also known as permeation enhancers.Main bodyTerpenes were considered as efficient skin permeation enhancers and are generally recognized as safe as per Food and Drug Administration. Terpenes improve the permeability of drugs either by destructing thestratum corneum’s tightly packed lipid framework, excessive diffusivity of drug in cell membrane or by rampant drug partitioning into epithelial cells. Various vesicular systems have been developed and utilized for the transdermal delivery of many drugs. Invasomes are one such novel vesicular system developed which are composed of phospholipids, ethanol and terpenes. The combined presence of ethanol and terpenes provides exceptional flexibility to the vesicles and improves the permeation across the barrier offered due to thestratum corneumas both ethanol and terpenes act as permeation enhancers. Therefore, utilization of invasomes as carriers to facilitate higher rate of drug permeation through the skin can be a very useful approach to improve transdermal drug delivery of a drug.ConclusionThe paper focuses on a broad updated view of terpenes as effective permeation enhancers and invasomes along with their applications in the pharmaceutical formulations.
Characteristics of reducing local scour around cylindrical pier using a horn-shaped collar
Authors: Luo Kedian , Si Yuhang , Lu Shaohua , Liang Boyang , Qi Hongliang 
Published: December 2022

AbstractLocal scour is the major cause of bridge water damage. The sediment in the riverbed around the pier is eroded and transported by water flow, leading to a loss of bridge foundation stability. In this study, a horn-shaped collar was proposed to mitigate local scour around bridge piers. The three design parameters (bottom diameter, vertical height, and curvature shape index) of the horn-shaped collar were studied under clear water condition, and the number of experimental tests was reduced to 25 by using Taguchi’s method. Main effect analysis was used to determine the optimum design parameters for the horn-shaped collar. The results show that the three design parameters have a significant effect on the scour reduction capacity of the horn-shaped collar, with the bottom diameter of the collar making the greatest contribution. The optimum values for the bottom diameter, vertical height, and curvature shape index are 5D, 0.25D, and 4, respectively (D represents the diameter of the pier), and the optimized shape of the horn-shaped collar reduces the maximum scour depth around the pier by 100% compared to the unprotected case. Based on the experimental data, prediction equations are developed for the maximum scour depth protected by a horn-shaped collar.
Suicidal ideation among people with disabilities during the COVID-19 pandemic in Bangladesh: prevalence and associated factors
Authors: Roy Nitai , Amin Md. Bony , Mamun Mohammed A. , Hossain Ekhtear , Aktarujjaman Md. , Sarker Bibhuti 
Published: December 2022

Background
Evidence from pandemic and pre-pandemic studies conducted globally indicates that people with disabilities (PWDs) have a higher risk for suicidality. However, none of these studies has assessed suicidality among PWDs in Bangladesh.

Aims
The purpose of this study was to determine the prevalence of and factors associated with suicidal ideation among PWDs during the COVID-19 pandemic in Bangladesh.

Method
Using a snowball sampling technique, a cross-sectional survey was conducted from February to April 2021 among PWDs from six districts in the northern region of Bangladesh. Information related to sociodemographic factors, clinical characteristics, behavioural factors and suicidal ideation was collected. Chi-squared test and logistic regression were used to describe the data and explain the relationship of factors associated with suicidal ideation.

Results
The prevalence of COVID-19-related past-year suicidal ideation was 23.9%. The factors associated with suicidal ideation included: age above 35 years, being female, acquiring a disability later in life, lack of sleep and current substance use. In addition, higher education appeared to be a protective factor against suicidal ideation.

Conclusions
This study highlighted that PWDs had an increased risk of suicide; that is, one-fourth of them had past-year suicidal ideation. This may have been because of COVID-19-related restrictions and stressors. Thus, the government and policy makers need to pay more attention to developing effective suicide assessment, treatment and management strategies, especially for at-risk groups, to minimise the impact of the COVID-19 outbreak.
Highly integrated hydrogen sensor based on inverse surface plasmon polaritons
Authors: Zhang Zheng , Song Gang , Duan Gaoyan , Lang Peilin 
Published: December 2022

Abstract
We report a novel hydrogen sensor based on inverse surface plasmon polaritons (ISPPs) which may be used in integrated optical circuit. If a light beam hits a prism with Kretschmann configuration at a proper angle, the surface plasmon polaritons (SPPs) will be excited at the surface of the metal film. And the angle depends on the optical properties of the film. We use a palladium (Pd) film which changes its dielectric function in hydrogen gas. Thus, the incident angle can be used to indicate the concentration of hydrogen. Our sensor inverted all the process: SPPs are excited by a grating integrated on the Pd film, and decoupled by the prism, the angle of departure will indicate the hydrogen concentration. According to our simulation, if the concentration of hydrogen increases by 1%, the angle changes by

and the intensity decreases by 1.55%. Our proposal can be used to improve the integration of ISPPs sensors.
Perioperative Evaluation and Management of Patients on Glucocorticoids
Authors: Chen Cardenas Stanley M , Santhanam Prasanna , Morris-Wiseman Lilah , Salvatori Roberto , Hamrahian Amir H 
Published: December 2022

Abstract
Myriad questions regarding perioperative management of patients on glucocorticoids (GCs) continue to be debated including which patients are at risk for adrenal insufficiency (AI), what is the correct dose and duration of supplemental GCs, or are they necessary for everyone? These questions remain partly unanswered due to the heterogeneity and low quality of data, studies with small sample sizes, and the limited number of randomized trials. To date, we know that although all routes of GC administration can result in hypothalamic-pituitary-adrenal (HPA) axis suppression, perioperative adrenal crisis is rare. Correlation between biochemical testing for AI and clinical events is lacking. Some of the current perioperative management recommendations based on daily GC dose and duration of therapy may be difficult to follow in clinical practice. The prospective and retrospective studies consistently report that continuing the daily dose of GCs perioperatively is not associated with a higher risk for adrenal crises in patients with GC-induced AI. Considering that oral GC intake may be unreliable in the early postoperative period, providing the daily GC plus a short course of IV hydrocortisone 25 to 100 mg per day based on the degree of surgical stress seems reasonable. In patients who have stopped GC therapy before surgery, careful assessment of the HPA axis is necessary to avoid an adrenal crisis. In conclusion, our literature review indicates that lower doses and shorter duration of supplemental GCs perioperatively are sufficient to maintain homeostasis. We emphasize the need for well-designed randomized studies on this frequently encountered clinical scenario.