bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nutritional Needs in Mental Healthcare: Study Protocol of a Prospective Analytic Observational Study Assessing Nutritional Status, Eating Behavior and Barriers to Healthy Eating in Psychiatric Inpatients and Outpatients Compared to Healthy Adults
Authors: Hotzy Florian , Risch Ladina , Mötteli Sonja 
Published: June 2022

BackgroundMental disorders are often associated with unhealthy eating behaviors and metabolic comorbidities. This can result in reduced life expectancy and poorer quality of life in people with mental disorders. This study protocol describes an observational study that examines the nutritional status and eating behaviors of people with severe mental illness (SMI) and the need for psychiatric treatment who were between 18 and 65 years old. In addition, the study focuses on possible barriers for healthy eating that have not yet been examined in this population.MethodsA total of 192 study participants will be recruited: 64 inpatients and 64 outpatients from the Psychiatric Hospital of the University of Zurich with SMI as well as 64 healthy individuals from the general population as a control group. The participants will be interviewed regarding their nutritional status, eating behavior, nutrition knowledge, food and cooking skills, personality, attitudes and feelings toward nutrition. In addition, the severity of symptoms and several control variables (e.g., sociodemographic variables and physical activity) will be assessed. For the patient samples, data will comprise routine medical data, and, if available, routine laboratory data. Inpatients will be interviewed once at the beginning of their treatment. Outpatients will be interviewed at the beginning and after 3 months of treatment (same interview questions). Healthy adults of the control group will be interviewed once at any time during the recruitment period.DiscussionThe described study will identify nutritional needs and possible barriers to healthy eating in patients with mental disorders. The results will help to define recommendations for nutritional risk screening in psychiatric patients and for planning effective nutritional interventions.
Anxiety and Food Addiction in Men and Women: Results From the Longitudinal LIFE-Adult-Study
Authors: Hussenoeder Felix S. , Pabst Alexander , Conrad Ines , Löbner Margrit , Engel Christoph , Zeynalova Samira , Reyes Nigar , Glaesmer Heide , Hinz Andreas , Witte Veronica , Schroeter Matthias L. , Wirkner Kerstin , Kirsten Toralf , Löffler Markus , Villringer Arno , Riedel-Heller Steffi G. 
Published: June 2022

BackgroundAnxiety is a widespread phenomenon, and it is connected to disordered eating and obesity. We want to analyze the connection between anxiety and food addiction (FA) over two points in time to better understand the directionality of the association. Since there are gender differences with regard to anxiety and eating, we are also interested in differences between men and women.MethodsWe used data from the population-based LIFE-Adult-Study (N = 1,474) at time 1 (baseline) and time 2 (first follow-up) to analyze the connections between anxiety (GAD-7) and FA (YFAS) using a multiple group latent cross-lagged panel model with female and male participants as groups. We controlled for age, marital status, socioeconomic status and social support.ResultsAnxiety (women: β = 0.50, p ≤ 0.001; men: β = 0.59, p ≤ 0.001) as well as FA (women: β = 0.37, p ≤ 0.001; men: β = 0.58, p ≤ 0.001) exhibited stability over time for both genders. We found a significant association between anxiety at time 1 and FA at time 2 for women (β = 0.25, p ≤ 0.001) but not for men (β = 0.04, p = 0.10), and significant associations between FA at time 1 and anxiety at time 2 for women (β = 0.23, p ≤ 0.001) as well as men (β = 0.21, p ≤ 0.001).ConclusionFood addiction longitudinally affects anxiety, independent of gender and other sociodemographic variables. In addition, anxiety affects subsequent FA as well, but only in women. Interventions that address FA could reduce anxiety in men and women, while interventions that mitigate anxiety could help prevent FA in women.
Effects of COVID-19-Related Anxiety and Sleep Problems on Loneliness and Feelings of School Refusal in Adolescents
Authors: Okajima Isa , Honda Yukako , Semba Osamu , Kiyota Yoji , Tani Yasuo 
Published: June 2022

BackgroundCOVID-19-related anxiety, sleep problems, and loneliness may be risk factors for school refusal in children and adolescents. However, few studies have examined the mechanisms by which these risk factors cause school refusal. This study examined the process by which COVID-19-related anxiety, sleep problems, and loneliness cause school refusal, using structural equation modeling.MethodsIn this cross-sectional questionnaire-based study, 256 (109 male, 147 female, mean age: 15.37 ± 0.48 years) senior high school students were asked to complete the Stress and Anxiety associated with Viral Epidemics-6 questionnaire to assess COVID-19-related anxiety, the Athens Insomnia Scale (AIS), Sleep Debt Index (SDI), and chronotype (MSFsc) to assess sleep problems, the Three-Item Loneliness Scale (TILS) to assess loneliness, and Feelings of School-Avoidance Scale (FSAS) to assess school refusal.ResultsStructural equation modeling showed that sleep problems affected loneliness (β = 0.52) and feelings of school refusal (β = 0.37), and that loneliness affected feelings of school refusal (β = 0.47). There was no significant pathway of COVID-19-related anxiety on sleep problems, loneliness, or feelings of school refusal. The indirect effect of sleep problems on feelings of school refusal through loneliness was significant. The results of hierarchical multiple regression analysis showed that AIS (β = 0.30) and SDI (β = 0.13) scores were associated with TILS, and AIS (β = 0.26) and MSFsc (β = −0.14) scores were associated with FSAS scores.ConclusionThe findings of this study showed that sleep problems affected feelings of school refusal via both direct and indirect pathways through the exacerbation of loneliness. To prevent school refusal in adolescents, addressing the indirect pathway via loneliness could be effective in improving insomnia and sleep debt, while addressing the direct pathway could be effective in improving insomnia and chronotype.
COVID-19 Preventive Measures in Northern California Jails: Perceived Deficiencies, Barriers, and Unintended Harms
Authors: Liu Yiran E. , LeBoa Christopher , Rodriguez Marcela , Sherif Beruk , Trinidad Chrisele , del Rosario Michael , Allen Sophie , Clifford Christine , Redding Jennifer , Chen Wei-ting , Rosas Lisa G. , Morales Carlos , Chyorny Alexander , Andrews Jason R. 
Published: June 2022

BackgroundCarceral facilities are high-risk settings for COVID-19 transmission. Little is known about the hidden burden of infection or practical barriers to infection control in these settings, especially in jails. There is also limited research on the mental health impacts of the pandemic among people living and working in carceral facilities.MethodsBetween July 8, 2020 and April 30, 2021, we performed SARS-CoV-2 rapid antibody testing and administered a questionnaire among residents and staff of four Northern California jails. We utilized multivariable logistic regression, adjusting for demographic and carceral characteristics, to analyze factors associated with prior infection, including perceived likelihood of prior infection and access to new masks. We additionally assessed the implementation of, perceptions toward, and impacts of COVID-19 policies in practice. We engaged stakeholder representatives, including incarcerated individuals, to guide study design, procedures, and results interpretation.ResultsWe enrolled 788 jail residents and 380 jail staff. Nearly half of residents and two-thirds of staff who were antibody-positive had not previously tested positive for COVID-19. Among residents without a prior COVID-19 diagnosis, antibody positivity was significantly associated with perceived likelihood of prior infection (adjusted OR = 8.9; 95% CI, 3.6–22.0). Residents who had flu-like illness in jail cited inadequate responses to reported illness and deterrents to symptom reporting, including fears of medical isolation and perceptions of medical neglect. Residents also disclosed deficient access to face masks, which was associated with antibody positivity (adjusted OR = 13.8, 95% CI, 1.8–107.0). Worsened mental health was pervasive among residents, attributed not only to fear of COVID-19 and unsanitary jail conditions but also to intensified isolation and deprivation due to pandemic restrictions on in-person visitation, programs, and recreation time.ConclusionCarceral settings present significant challenges to maintaining infection control and human rights. Custody officials should work diligently to transform the conditions of medical isolation, which could mitigate deterrents to symptom reporting. Furthermore, they should minimize use of restrictive measures like lockdowns and suspension of visitation that exacerbate the mental health harms of incarceration. Instead, custody officials should ensure comprehensive implementation of other preventive strategies like masking, testing, and vaccination, in conjunction with multisector efforts to advance decarceration.
Cost-Effectiveness Analysis of Pembrolizumab Plus Chemotherapy vs. Chemotherapy Alone as First-Line Treatment in Patients With Esophageal Squamous Cell Carcinoma and PD-L1 CPS of 10 or More
Authors: Zheng Zhiwei , Lin Jingrong , Zhu Huide , Cai Hongfu 
Published: June 2022

BackgroundThis study aimed to analyze the economics of pembrolizumab plus chemotherapy as first-line treatment in patients with esophageal squamous cell carcinoma (ESCC) and programmed cell death-Ligand 1 (PD-L1) combined positive score (CPS) of 10 or more in China.MethodsBased on the advanced ESCC of the KEYNOTE-590 clinical trial data, a Markov model was performed to simulate the clinical course and evaluate the patient's total lifetime, total costs, quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratio (ICER) for pembrolizumab plus chemotherapy (cisplatin and 5-fluorouracil) vs. chemotherapy alone in first-line treatment of ESCC and PD-L1 CPS of 10 or more. Utility values and direct costs related to the treatments were gathered from the published literature data. One-way and probabilistic sensitivity analyses were conducted to check the stability of the model.ResultsThe baseline analysis indicated that the incremental effectiveness and cost of pembrolizumab plus chemotherapy vs. chemotherapy alone added 1.23 QALYs and resulted in an incremental cost of $51,320.22, which had an ICER of $41,805.12/QALY, higher than the willingness-to-pay (WTP) threshold of China ($37,663.26/QALY). The sensitivity analysis demonstrated that the ICERs were most sensitive to the cycle of pembrolizumab used and the cost of pembrolizumab.ConclusionThe result of our present analysis suggests that the addition of pembrolizumab plus chemotherapy as first-line treatment might not be cost-effective for patients with ESCC and PD-L1 CPS of 10 or more in China.
Design and Cross-Cultural Invariance of the COVID-19 Vaccine Conspiracy Beliefs Scale (COVID-VCBS) in 13 Latin American Countries
Authors: Caycho-Rodríguez Tomás , Valencia Pablo D. , Ventura-León José , Vilca Lindsey W. , Carbajal-León Carlos , Reyes-Bossio Mario , White Michael , Rojas-Jara Claudio , Polanco-Carrasco Roberto , Gallegos Miguel , Cervigni Mauricio , Martino Pablo , Palacios Diego Alejandro , Moreta-Herrera Rodrigo , Samaniego-Pinho Antonio , Lobos-Rivera Marlon Elías , Figares Andrés Buschiazzo , Puerta-Cortés Diana Ximena , Corrales-Reyes Ibraín Enrique , Calderón Raymundo , Tapia Bismarck Pinto , Arias Gallegos Walter L. , Petzold Olimpia 
Published: June 2022

AimsOver the past 2 years, the vaccine conspiracy beliefs construct has been used in a number of different studies. These publications have assessed the determinants and outcomes of vaccine conspiracy beliefs using, in some cases, pooled data from different countries, and compared the results across these contexts. However, studies often do not consider measurement invariance as a necessary requirement for comparative analyses. Therefore, the aim of this study was to develop and evaluate the cross-cultural MI of the COVID-19 Vaccine Conspiracy Beliefs Scale (COVID-VCBS) in 12 Latin American countries.MethodsConfirmatory factor analysis, item response theory analysis and alignment method were applied to test measurement invariance in a large number of groups.ResultsThe COVID-VCBS showed robust psychometric properties and measurement invariance for both factor loadings and crosstabs. Also, a higher level of acceptance of conspiracy beliefs about vaccines is necessary to respond to higher response categories. Similarly, greater acceptance of conspiracy beliefs about COVID-19 vaccines was related to a lower intention to be vaccinated.ConclusionThe results allow for improved understanding of conspiracy beliefs about COVID-19 vaccines in the countries assessed; furthermore, they provide researchers and practitioners with an invariant measure that they can use in cross-cultural studies in Latin America. However, further studies are needed to test invariance in other countries, with the goal of developing a truly international measure of conspiracy beliefs about COVID-19 vaccines.
A New Parameter of Hip Instability in Developmental Dysplasia of the Hip (DDH): Teardrop Distance
Authors: Yang Guoyue , Zhang Zhendong , Hou Xiaobin , Luo Dianzhong , Cheng Hui , Xiao Kai , Liu Hui , Zhang Hong 
Published: June 2022

BackgroundHip instability is one of the etiologies of accelerated onset of osteoarthritis in developmental dysplasia of the hip (DDH). There are some radiological parameters for hip instability in hip dysplasia like broken shenton’s line, elevated acetabular index, reduced lateral center edge angle (LCEA), upsloping lateral sourcil. We have discovered a new index of teardrop distance (TD) for assessing instability. Herein, we hypothesized that increased TD could be used as evidence of hip instability in DDH patients, which we verified using TD as an auxiliary diagnostic parameter for DDH, from supine to standing position.MethodsFemale DDH patients undergoing Bernese periacetabular osteotomy (PAO) were enrolled in the DDH group, and normal female volunteers were in the control group. Anteroposterior radiographs of the pelvis in the supine and standing positions were taken, and LCEA, Tönnis angle (TA), sharp angle (SA), and TD were tested using Stata software to analyze the changes between supine and standing anteroposterior pelvic radiographs.ResultsThere were 26 female volunteers with 52 hips in the control group: supine TD 6.80 ± 0.98 mm, standing TD 6.65 ± 1.3 mm (P &gt; 0.05). A total of 78 patients with 135 hips were included in the DDH group: supine TD 10.51 ± 3.50 mm, standing TD 10.93 ± 4.23 mm (P &lt; 0.05). In either supine or standing position, TD in the DDH group was significantly wider than that in the control group (P &lt; 0.05). In the DDH group, TD was correlated with TA and LCEA (rp 0.494–0.588, P &lt; 0.05); TD was not correlated with SA, weight, or BMI (P &gt; 0.05). There was a weak correlation between TD difference and standing LCEA (rp −0.276, P &lt; 0.05).ConclusionTD &gt; 10 mm was a common imaging feature of DDH. It increased from supine to standing position, thus indicating hip instability in DDH patients. The hip parameters of both positions should be compared, fully considering the factors of hip stability.
A Narrative Review of Postoperative Anticoagulation Therapy for Congenital Cardiac Disease
Authors: Boucher Alexander A. , Heneghan Julia A. , Jang Subin , Spillane Kaitlyn A. , Abarbanell Aaron M. , Steiner Marie E. , Meyer Andrew D. 
Published: June 2022

Congenital heart disease encompasses a range of cardiac birth defects. Some defects require early and complex surgical intervention and post-operative thromboprophylaxis primarily for valve, conduit, and shunt patency. Antiplatelet and anticoagulant management strategies vary considerably and may or may not align with recognized consensus practice guidelines. In addition, newer anticoagulant agents are being increasingly used in children, but these medications are not addressed in most consensus statements.This narrative review evaluated the literature from 2011 through 2021 on the topic of postoperative thromboprophylaxis after congenital heart disease operations. The search was focused on the descriptions and results of pediatric studies for replacement and/or repair of heart valves, shunts, conduits, and other congenital heart disease operations. Wide variability in practice exists and, as was true a decade ago, few randomized controlled trials have been conducted. Aspirin, warfarin, and perioperative heparin remain the most commonly used agents with varying dosing, duration, and monitoring strategies, making comparisons difficult. Only recently have data on direct oral anticoagulants been published in children, suggesting evolving paradigms of care. Our findings highlight the need for more research to strengthen the evidence for standardized thromboprophylaxis strategies.
Factors Affecting the Postoperative Bowel Function and Recurrence of Surgery for Intestinal Deep Endometriosis
Authors: Xu Ping , Wang Jianzhang , Zhang Yanan , Zhu Libo , Zhang Xinmei 
Published: June 2022

ObjectiveThis study aims to evaluate the factors associated with complications and long-term results in the surgical treatment of intestinal deep endometriosis and to figure out the optimized treatment measures for bowel endometriosis.MethodsA retrospective study was performed in a single center in China. Medical charts were reviewed from 61 women undergoing surgical treatment for bowel endometriosis between January 2013 and August 2019 in the Department of General Gynecology, Women’s Hospital School of Medicine Zhejiang University. Multivariate regression analysis was utilized to investigate the impact of the stages of endometriosis and surgical steps (independent risk factors) on complications (and postoperative bowel dysfunction). The clinical characters, surgical procedures, postoperative treatment, complications, and recurrence rate were summarized and analyzed by using Lasso regression.ResultsSurgery type was the most important independent risk factor related to postoperative abnormal defecation in intestinal deep endometriosis patients (P &lt; 0.05, OR = 34.133). Infection is the most important independent risk factor related to both postoperative complications (OR = 96.931) and recurrences after conservative surgery (OR = 4.667). Surgery type and age were significantly related to recurrences after conservative surgery.ConclusionsWe recommended conservative operation especially full-thickness disc excision to improve the quality of life of intestinal deep endometriosis patients. In addition, prevention of infection is very important to reduce the postoperative complications rate and the recurrence rate.
Teknologi Attractor Cumi Rangka Besi : Upaya Meningkatkan Produktifitas Sumberdaya Perikanan di Perairan Desa Kalasey Dua, Kecamatan Mandolang Kabupaten Minahasa Provinsi Sulawesi Utara
Authors: Patty Wilhelmina , Pangalila Fransisco P. T. , Kayadoe Mariana E. , Majore Eldy , Dien Heffry V. 
Published: June 2022

Kondisi terumbu karang diperairan Sulawesi Utara, khusus di perairan Desa Kalasey Dua sudah dirusakan oleh kegiatan reklamasi yang dimulai sejak Tahun 2011. Dampak ekologi yang sudah dirasakan oleh masyarakat nelayan akibat proyek reklamasi pantai di Kalasey antara lain: rusaknya lahan mangrove dan terumbu karang akibat penimbunan material tanah dan batu secara langsung ke dalam perairan. Akibat rusaknya ekosistim pesisir di wilayah pesisir seperti terumbu karang, algae dll, membuat berkurangnya telur dan individu dewasa cumi-cumi di wilayah pesisir. Salah satu proses yang dilakukan untuk dapat mempertahankan kelangsungan generasi atau memcegah kepunahan suatu sumberdaya adalah reproduksi atau perkembangbiakan. Dalam konteks penyediaan sumber hidup alternatif, maka Teknologi squid attractor (atraktor cumi). merupakan salah satu sarana buatan yang dapat digunakan untuk meningkatkan daya dukung dan kelestarian sumberdaya cumi-cumi. Squid attractor mempunyai fungsi utama sebagai tempat melekatkan telur cumi-cumi sampai menetas; dan dalam kondisi tertentu sarana ini dapat berfungsi sebagai fishing ground. Melihat Manfaat dari teknologi atraktor cumi ini, maka beberapa atraktor cumi-cumi rangka besi telah diletakan di perairan Desa Kalasey Dua, dengan tujuan utama memperkaya sumberdaya cumi-cumi di kawasan pesisir, dengan desain atraktor yang dimodifikasi sehingga dalam pembuatanya mudah dan ramah lingkungan. Penerapan teknologi Attractor cumi ini memilik tingkat efektifitasnya antara 50 – 100 %, atau sebahagian besar sampai seluruh tali ditempeli dengan telur. Hal ini berarti ada penambahan stock sumberdaya cumi di perairan Desa Kalesey dua serta Konservasi lingkungan perairan Desa Kalasey dua.
Keadaan Umum Perikanan Tangkap di Kelurahan Binuang Kecamatan Lembe Utara Kota Bitung
Authors: Urulamo Wilston , Manu Lusia 
Published: June 2022

This study aims to determine the general condition of capture fisheries in Binuang sub-district, North Lembeh District, Bitung City. The data collection method is carried out through a survey which is based on the descriptive method. Binuang sub-distric has an area of 320 ha, where most of the population works as fishermen, amounting to 174 people (62.49%). There are four kinds of fishing gears used, namely beach seine (soma dampar,15 units) (8), lift net (bagan, 5 units), tuna hand line ( 12 units) and hand line (noru, 170 units). The dominant fish catches are mackeral (Selaroides leptolepis), mackerel scard (Decapterus sp) and anchovy (Stolephorus sp), squid (Loligo sp.), long jawed mackerel (Rastrelliger sp) and tuna (Thunnus sp).Tujuan dari penelitian ini adalah untuk mendeskripsikan keadaan umum perikanan tangkap di Kelurahan Binuang, Kecamatan Lembeh Utara, Kota Bitung. Pengumpulan data dilakukan melalui pengamatan langsung, wawancara dan pengutipan data sekunder yang tersedia di kantor Kelurahan Binuang yang didasarkan pada metode deskriptif. Kelurahan Binuang memiliki luas 320 ha dengan jumlah penduduk 908 jiwa, dimana sebagian besar penduduknya bermata pencarian sebagai nelayan yang berjumlah 174 orang (62.49 %). Alat tangkap yang digunakan terdiri dari empat jenis, yaitu soma dampar (pukat pantai) 15 unit, bagan 5 unit, pancing tuna 12 unit dan pancing noru sebanyak kurang lebih 170 unit. Hasil tangkapan ikan yang dominan adalah selar (Selaroides leptolepis), layang (Decapterus sp), teri (Stolephorus sp), cumi-cumi (Loligo sp.), kembung (Rastrelliger sp) dan tuna (Thunnus sp).
Studi Pola Usaha penangkapan ikan pelagis kecil pada KM. Lionel di Pulau Buhias
Authors: Bawingkung Revi Reinaldi , Kayadoe Mariana Elizabeth , Dien Heffry Veibert 
Published: June 2022

Ikan merupakan sumberdaya yang berpotensi dari segi jumlah dan jenisnya di Indonesia. Pulau Buhias merupakan salah satu pulau yang terdapat digugusan pulau di Kabupaten Siau Tagulandang Biaro (SITARO), tepatnya di Kecamatan Siau Timur Selatan yang dapat dicapai dalam waktu 30 menit dari pelabuhan Ulu Siau. Sebagian besar penduduknya adalah nelayan tradisional dengan tingkat kesejahteraan yang cukup memadai. Penelitian ini bertujuan untuk mengetahui upaya penangkapan, pola usaha bagi hasil serta pendapatan nelayan yang ada di Buhias. Penelitian ini menggunakan penelitian kualitatif dengan pendekatan studi kasus. Hasil penelitian menunjukan Upaya penangkapan KM. Lionel menggunakan Purse Seine dengan cara melingkari gerombolan ikan. Rata- rata pendapatan per bulan nelayan Kapal Soma Pajeko Lionel adalah Rp.698.502,-. Sehingga sebagian nelayan melakukan kegiatan lain yang dapat menunjang perekonomian keluarga seperti berjualan ikan. Sedangkan untuk sistem pembagian hasil di pulau Buhias menggunakan sistem hasil tangkapan dikurangi biaya operasional trip dan hasil pendapatan bersih dibagi berdasarkan presentase yang telah disepakati.