bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ocular Hypotony after Glaucoma Surgery
Authors: Ghobashy Heba Mohammed , Elmaria Ahmed Fekry , Ghoneim Ahmed Mohammed , Eid Tarek El Mohammadi 
Published: August 2022

Background: Postoperative hypotony is associated with choroidal effusion, suprachoroidal haemorrhage, aqueous misdirection syndrome (malignant glaucoma), choroidal folds and hypotony maculopathy, anterior chamber (AC) shallowness or loss and subsequent failure of the original filtration of procedure. This work aimed to study the causes, risk factors, adverse effects, and management plans of ocular hypotony after different glaucoma surgeries.
Methods: This retrospective study was carried out on 205 eyes underwent glaucoma surgery with follow up for more than 3 months. Patients were divided into two groups: 30 cases were diagnosed with post-operative hypotony, 175 eyes were without hypotony. Patients were subjected to glaucoma diagnosis, type of glaucoma operation and recorded IOP for 3 months at least.
Results: CPC, Visco-Trab, Phaco Visco-Trab Visco and express valve were significantly different between the two groups (P=0.049, P=0.012, P=0.043 and P<0.001 respectively) and other types of operation were insignificantly different between the two groups. IOP was significantly decreased at first diagnosis of hypotony and at last follow up compared to before operation (P value <0.001). IOP at last follow up was significantly increased compared to first diagnosis of hypotony (P value <0.001). Criteria of hypotony eyes were insignificantly different between patients needed surgical intervention and no surgical intervention.
Conclusions: Postoperative hypotony was most common in pseudo-exfoliative glaucoma cases compared to other glaucoma types. While the most type of glaucoma surgery that was associated with postoperative hypotony was viscocanalostomy combined with express shunt. The adverse effects reported in our study were choroidal effusion and hypotony maculopathy.
Driving forces behind the fluctuating growth of the number of successful nests in an inland population of white‐tailed eagles in Hokkaido, Japan
Authors: Ohtsubo Masanori , Umatani Yoshiyuki , Okuda Atushi , Saitoh Takashi 
Published: August 2022

AbstractThis study aimed to describe the change in the number of successful nests of the white‐tailed eagle, Haliaeetus albicilla, for 25 years (1997–2021) along the Teshio River (100 km), Japan, which is a new habitat for this endangered species and identify factors driving the number of nests. The number of nests grew from two to nine. The logistic function fitted in well with the growth, and the capacity of the study area sustaining the successful nests was estimated at 6.5. The precipitation in January and April explained the deviation of the observed values from the model prediction. In particular, heavy rain in April was associated with low numbers. Forty‐six nest remains were collected from 17 nest locations. Twelve genera of birds, six genera of mammals, and four genera of fishes were identified. Fish and bird items occupied 93.6% of prey individuals. The fish proportion was similar between high‐performance years when the observed number of successful nests was higher than the model prediction and low‐performance years with a lower number than the prediction (55.2% and 51.0%). However, it was higher in the nests with two fledglings (63.0%) than those with a single fledgling (41.5%). The nearest neighbor distance (NND) of the successful nests declined with the increase in the number of nests. Based on territory size (the mean NND = 7.8 km), the study area can hold 13 nests. The process and mechanism of the dynamics of the number of nests were discussed, focusing on territoriality and weather effects.
Active disturbance rejection adaptive control of multi‐degrees of freedom hydraulic manipulators
Authors: Sun Xin , Yao Jianyong , Deng Wenxiang 
Published: August 2022

SummaryThis article investigates the precise motion control of multi‐degrees of freedom (DoF) hydraulic manipulators, and proposes an active disturbance rejection adaptive control (ADRAC) architecture based on full state feedback with consideration of both unmatched and matched uncertainties, that is, parametric uncertainties and uncertain nonlinearities. The new control strategy integrates adaptive control with extended state observer (ESO) via the backstepping method. Parametric uncertainties are handled by the synthesized adaptive law, and ESO is designed to estimate the remaining uncertainties before being compensated in a feedforward way. In particular, the unmatched and matched uncertainties can be observed in real‐time by constructing an ESO for each channel of the hydraulic manipulator system. The burden on ESO should be greatly reduced since parameter adaptation offsets most parametric uncertainties. Accordingly, high‐gain feedback is avoided in the resulting controller, and improved servo performance can thus be expected. In theory, the suggested ADRAC controller can attain asymptotic tracking performance under the influence of not only parametric uncertainties derived from various hydraulic parameters but also invariant disturbances. Furthermore, when uncertain nonlinearities become time‐variant, prescribed transient tracking performance and final tracking accuracy can also be ensured. Comparative simulations concerning both matched and unmatched uncertainties are obtained to illustrate the high tracking performance nature of the developed control algorithm.
3D Printing Nanostructured Solid Polymer Electrolytes with High Modulus and Conductivity
Authors: Lee Kenny , Shang Yuan , Bobrin Valentin A. , Kuchel Rhiannon , Kundu Dipan , Corrigan Nathaniel , Boyer Cyrille 
Published: August 2022

AbstractThe development of advanced solid‐state energy‐storage devices is contingent upon finding new ways to produce and manufacture scalable, high‐modulus solid‐state electrolytes that can simultaneously provide high ionic conductivity and robust mechanical integrity. In this work, an efficient one‐step process to manufacture solid polymer electrolytes composed of nanoscale ion‐conducting channels embedded in a rigid crosslinked polymer matrix via Digital Light Processing 3D printing is reported. A visible‐light‐mediated polymerization‐induced microphase‐separation approach is utilized, which produces materials with two chemically independent nanoscale domains with highly tunable nanoarchitectures. By producing materials containing a poly(ethylene oxide) domain swelled with an ionic liquid, robust solid polymer electrolytes with outstanding room‐temperature (22 °C) shear modulus (G’ > 108 Pa) and ionic conductivities up to σ = 3 × 10−4 S cm−1 are achieved. The nanostructured 3D‐printed electrolytes are fabricated into a custom geometry and employed in a symmetric carbon supercapacitor, demonstrating the scalability of the fabrication and the functionality of the electrolyte. Critically, these high‐performance materials are manufactured on demand using inexpensive and commercially available 3D printers, which allows the facile modular design of solid polymer electrolytes with custom geometries.
An Automated System for Strain Engineering and Straintronics of 2D Materials
Authors: Çakıroğlu Onur , Island Joshua O. , Xie Yong , Frisenda Riccardo , Castellanos‐Gomez Andres 
Published: August 2022

AbstractThis work presents an automated three‐point bending apparatus that can be used to study strain engineering and straintronics in 2D materials. This work benchmarks the system by reporting reproducible strain tuned micro‐reflectance, Raman, and photoluminescence spectra for monolayer molybdenum disulfide (MoS2). These results are in good agreement with reported literature using conventional bending apparatus. This work further utilizes the system to automate strain investigations of straintronic devices by measuring the piezoresistive effect and the strain effect on photoresponse in an MoS2 electrical device. The details of the construction of the straightforward system are given and it is anticipated that it can be easily implemented for study of strain engineering and straintronics in a wide variety of 2D material systems.
A Solid Electrolyte Based on Electrochemical Active Li4Ti5O12 with PVDF for Solid State Lithium Metal Battery
Authors: Zhou Qi , Yang Xiaoyan , Xiong Xiaosong , Zhang Qianyu , Peng Bohao , Chen Yuhui , Wang Zhaogen , Fu Lijun , Wu Yuping 
Published: August 2022

AbstractIn parallel with researches unveiling the nature and mechanism in solid state battery, numbers of investigations have been pursuing methods to stabilize their performance as well as to reduce the cost. Simple preparation and earth‐abundant ingredients are preconditions for a solid state electrolyte to be suitable for scalable production. In this work, a commercial anode active material, spinel Li4Ti5O12, is introduced for the first time, which has high ionic conductivity to sustain high rate charge/discharge with considerable high performance/cost ratio, into poly(vinylidene fluoride) to achieve a composite solid electrolyte. The membrane solid electrolyte containing 80 wt% of the Li4Ti5O12 (LTO‐8) shows outstanding ionic conductivity of 2.87 × 10−4 S cm−1 at 35 °C and inhibits electronic conductive network. The self‐sacrificed interface contributes to the stabilized performance of the composite. Li||LiFePO4 cells with LTO‐8 present a discharge specific capacity of 150 mAh g−1 at 0.5C and a considerable average specific capacity of 119 mAh g−1 under 5C in 400 cycles, demonstrating its excellent working performance. This investigation provides promising application of Li4Ti5O12 for solid state electrolytes, which is superior to the reported solid state electrolytes in comprehensive performance, and surely paves another commercial way to solid state batteries.
Ionenadsorption und ‐desorption an der CaF2‐Wasser‐Grenzfläche untersucht mit Flussexperimenten und Schwingungsspektroskopie
Authors: Ober Patrick , Hunger Johannes , Kolbinger Sophia H. , Backus Ellen H. G. , Bonn Mischa 
Published: August 2022

AbstractDie Auflösung von Mineralien in Kontakt mit Wasser spielt eine entscheidende Rolle in der Geochemie. Einblicke in die Grenzflächenchemie auf molekularer Ebene zu erhalten, gestaltet sich jedoch schwierig. Beim Auflösen werden typischerweise Ionen an der Oberfläche freigesetzt, die eine geladene Mineraloberfläche entstehen lassen. Diese Ladung beeinflusst die Ausrichtung der Wassermoleküle an der Grenzfläche, was mittels oberflächenspezifischer Schwingungsspektroskopie auf Basis der Summenfrequenzerzeugung (v‐SFG‐Spektroskopie) untersucht werden kann. Die aktuellsten spektroskopischen Untersuchungen lassen darauf schließen, dass bei der Fluorit‐Wasser‐Grenzfläche die Adsorption und Desorption von Fluoridionen die Oberflächenladung bestimmt. Dies steht im Gegensatz zu älteren Zeta‐Potential‐Messungen, welche diese Rolle den Calciumionen zuschrieben. Durch Kombination von v‐SFG‐Spektroskopie und Flussexperimenten mit systematisch unterdrückter Ionenfreisetzung wird das Zusammenspiel von dominanter Fluorid und schwacher Calciumionen Adsorption/Desorption entdeckt und löst somit die Kontroverse in der Literatur. Hierbei konnten wir abschätzen, dass der Beitrag von Calcium um Größenordnungen geringer ist, was die Empfindlichkeit unseres Ansatzes unterstreicht.
Struktur‐Wirkungsbeziehung von an zyklische Zell‐penetrierende Peptide gebundenen DABCYL‐Derivaten für den Transport von synthetischen Proteinen in lebende Zellen
Authors: Saha Abhishek , Mandal Shaswati , Arafiles Jan Vincent V. , Gómez‐González Jacobo , Hackenberger Christian P. R. , Brik Ashraf 
Published: August 2022

AbstractDie Modifizierung zyklischer zelldurchdringender Deca‐Arginin (cR10)‐Peptide mit 4‐(4‐Dimethylaminophenylazo)‐benzoesäure (DABCYL) verbessert die Aufnahmeeffizienz synthetischer Ubiquitine (Ub) in lebende Zellen. Um die Rolle der DABCYL‐Komponente zu untersuchen, haben wir Zeitraffermikroskopie und Fluoreszenz‐Lifetime‐Imaging‐Mikroskopie (FLIM) von fluoreszierendem DABCYL‐R10 durchgeführt, um die Auswirkungen auf den Zelleintritt durch die Bildung von Nukleationszonen (nucleation zones) zu bewerten. Darüber hinaus haben wir eine Struktur‐Wirkungsstudie mit dreizehn an CPP gekoppelten DABCYL‐Derivaten durchgeführt, um ihre Auswirkungen auf die Effizienz der Zellaufnahme zu untersuchen, wenn sie über Disulfidbindungen an Mono‐Ub konjugiert sind. Unsere Ergebnisse zeigen, dass wir allein durch Strukturvariationen der DABCYL‐Komponente bei nanomolarer Konzentration eine Verdreifachung der zytosolischen Aaufnahme von Ub erreichen konnten, was Studien zu verschiedenen intrazellulären Prozessen im Zusammenhang mit der Ub‐Signalgebung ermöglicht.
An Anticancer Rhenium Tricarbonyl Targets Fe−S Cluster Biogenesis in Ovarian Cancer Cells
Authors: Neuditschko Benjamin , King A. Paden , Huang Zhouyang , Janker Lukas , Bileck Andrea , Borutzki Yasmin , Marker Sierra C. , Gerner Christopher , Wilson Justin J. , Meier‐Menches Samuel M. 
Published: August 2022

AbstractTarget identification remains a critical challenge in inorganic drug discovery to deconvolute potential polypharmacology. Herein, we describe an improved approach to prioritize candidate protein targets based on a combination of dose‐dependent chemoproteomics and treatment effects in living cancer cells for the rhenium tricarbonyl compound TRIP. Chemoproteomics revealed 89 distinct dose‐dependent targets with concentrations of competitive saturation between 0.1 and 32 μM despite the broad proteotoxic effects of TRIP. Target‐response networks revealed two highly probable targets of which the Fe−S cluster biogenesis factor NUBP2 was competitively saturated by free TRIP at nanomolar concentrations. Importantly, TRIP treatment led to a down‐regulation of Fe−S cluster containing proteins and upregulated ferritin. Fe−S cluster depletion was further verified by assessing mitochondrial bioenergetics. Consequently, TRIP emerges as a first‐in‐class modulator of the scaffold protein NUBP2, which disturbs Fe−S cluster biogenesis at sub‐cytotoxic concentrations in ovarian cancer cells.
Extracellular Matrix Targeted MRI Probes
Authors: Digilio Giuseppe , Lacerda Sara , Lavin Plaza Begoña , Phinikaridou Alkystis 
Published: August 2022

AbstractDysregulated remodeling of the extracellular matrix (ECM) can lead to excessive accumulation of ECM proteins (primarily collagen, elastin/ tropoelastin, fibronectin and fibrin) resulting in tissue fibrosis. In many pathologies, changes in the molecular pattern of ECM components have been related to the progression and severity of fibrosis. Thus, magnetic resonance imaging (MRI) probes sensing specific ECM components hold promise for accurate staging of fibrotic diseases. This paper focuses on gadolinium‐based contrast agents (GBCA) targeted to ECM components, including structural proteins and enzymes. According to available examples, they can be grouped into: 1) GBCA conjugated to targeting vectors that recognize and non‐covalently bind to specific sites on the molecular target; 2) GBCA carrying a reactive chemical function able to bind covalently to the complementary chemical function of the molecular target; and 3) enzyme‐responsive probes, whose relaxivity and pharmacokinetics change after enzymatic processing. Pros and cons of each approach are discussed.
Perioperative Management Strategies for the COVID‐19 Pandemic at a Facility in China
Authors: Bian Dongmei , Jia Weina , Wang Yana , Ma Na , Wang Yu , Wang Qian 
Published: August 2022

ABSTRACTThe spread of coronavirus disease 2019 posed a public health crisis beginning in January 2020, affecting hospitals and health care personnel worldwide and disrupting perioperative services. Organization leaders at Xijing Hospital, Xi’an, China, developed a mitigation system for the OR that involved creating a pandemic response team to identify and implement appropriate infection control practices to prevent virus transmission. The leaders addressed managing the daily surgery schedule through patient screening and a focus on the urgency and volume of procedures. They required increased use of personal protective equipment and more stringent cleaning and disinfection protocols and ensured that the physical and mental health of staff members were monitored and prioritized. This article describes how leaders implemented these enhanced processes to protect personnel from infection as they continued to provide patient care. It also describes how high‐risk procedures involving patients with confirmed or suspected infections were managed and discusses lessons learned.
Surface modification of cellulose nanofibers by oxidative polymerization of tannic acid/ethanediamine and their polyvinylalcohol composites
Authors: Liu Jin , Huang Hong , Zhou Danling 
Published: August 2022

AbstractThis paper reported a facile and green method for surface functionalization of cellulose nanofiber (CNF) by oxidative polymerization of tannic acid (TA) and ethanediamine. The modified CNF (T‐CNF) was then used as filler for constructing polyvinylalcohol (PVA) composites. Experimental results suggested that the surface polar groups on CNF were increased after modification. The abundant surface polar groups allowed the homogeneous dispersion of T‐CNF in PVA matrix, and the formation of hydrogen bonds between fillers and matrix. This interfacial interaction and the high aspect ratio of T‐CNF have restricted the thermal mobility of polymer chains and increased the glass transition temperature and melting temperature of PVA. Tensile test suggested the good mechanical properties of composites, and the reinforcement effect of T‐CNF on PVA was better than that of un‐modified CNF. The good free radical scavenging ability of polymerized TA also improved the thermal stability of composites and endowed the composites with good antioxidant property. The T‐CNF/PVA composites with improved properties hold great promising applications in fields such as packaging, adhesive and coating. This work is expected to provide alternative and green approach for the surface modification of CNF and the preparation of multifunctional CNF composites with good properties.
Preparation of bis‐epoxy end capped macromonomers through anionic orRAFTpolymerization
Authors: Gao Binglun , Sun Lianwei , Chen Xin , Zhai Xiaobo , Zheng Junchi , Ye Xin , Lu Jianmin , Feng Anchao , Zhang Liqun 
Published: August 2022

AbstractThe focus of this paper is to report the quantitative synthesis of bis‐epoxy end functionalized polyisoprene (BETPI) macromonomers by anionic polymerization and reversible addition fragmentation chain transfer (RAFT) polymerization. For anionic polymerization, more stable and sterically hindered living anions polyisoprene (Li+‐PIp‐Li+) react with epichlorohydrin (ECH) for the synthesis of well‐defined BETPI. For the high‐pressure RAFT polymerization, a novel bis‐epoxy end functionalized trithiocarbonate (BODAAT) is designed as RAFT agent for the polymerization of isoprene monomer to obtain well‐defined BETPI. The functionalities of the resulting BETPI are analyzed by Fourier transform infrared spectroscopy (FT‐IR), NMR, and size exclusion chromatography (SEC). Through two polymerization methods, the BETPI with 600–1000 Da of molecular weight and over 75% of epoxy end capping rate is obtained, which can be further utilized as highly reactive liquid macromonomers.
Insights into concomitant enhancements of dielectric properties and thermal conductivity of PVDF composites filled with core@double‐shell structured Zn@ZnO@PS particles
Authors: Yao Tian , Zhou Wenying , Peng Weiwei , Zhou Juanjuan , Li Ting , Wu Hongju , Zheng Jian , Lin Na , Liu Dengfeng , Hou Chunyou 
Published: August 2022

AbstractIn order to synchronously improve dielectric permittivity (ε′), breakdown strength (Eb), and thermal conductivity (TC) while inhibiting dissipation factor (tan δ) of raw Zn (Zinc)/PVDF (poly[vinylidene fluoride]) composites, two kinds of core‐shell structured particles of Zn@ZnO (zinc oxide) and Zn@ZnO@PS (polystyrene) were synthesized by high‐temperature oxidation followed by suspension polymerization, then they were composited with PVDF to elaborately generate morphology‐controllable high‐ε′ but low loss, and high TC composites. The results confirm that both the Zn@ZnO/PVDF and Zn@ZnO@PS/PVDF composites show markedly improved ε′, suppressed tan δ and conductivity over the original Zn/PVDF because of the induced multiple polarizations in the Zn@ZnO and Zn@ZnO@PS configurations and the barrier effect of constructed shells on direct contact of Zn particles. The second organic PS shell inhibits the loss and conductivity due to its high‐electrical resistivity, and further boosts the Eb and TC of the composites owing to enhanced interfacial compatibility between the Zn@ZnO and PVDF, which lessens the local electric field distortion and concentration, and therefore, promotes phonon transport across the interfaces through suppressing the thermal interfacial resistance. The prepared Zn@ZnO@PS/PVDF with a high Eb and ε′ but low tan δ, as well as enhanced TC, exhibit appealing potential applications in microelectronic devices and power equipment.
Langzeitmessungen an einer vorgespannten integralen Rahmenbrücke mit bewehrten Betongelenken – Vergleich Messergebnisse mit numerischen Simulationen – eine Gegenüberstellung nach 8 Jahren Messdauer
Authors: Vill Markus , Vospernig Michael , Reiterer Michael , Hüngsberg Alfred , Kari Hannes 
Published: August 2022

AbstractIm Rahmen des durch die ÖBB‐Infrastruktur AG initiierten Forschungsprojekts im Zuge der Errichtung einer Straßenbrücke beim Neubau des Semmering‐Basistunnels in Österreich wurden umfangreiche Langzeitmessungen des tatsächlichen Bauwerksverhaltens ab Herstellung einer Brücke im Jahr 2014 durchgeführt. Bei der vorliegenden Brücke handelt es sich um eine integrale vorgespannte Rahmenbrücke mit Betongelenken. Bei der Errichtung der Brücke wurden zur Langzeitmessung der Verformungen, Verdrehungen, Temperaturänderungen und Erddruckspannungen unterschiedliche Messsensoren sowohl innerhalb der Betonquerschnitte vor Betonage als auch an der Oberfläche der Betontragstruktur installiert. Die Messungen laufen nun seit der Errichtung der Brücke im Jahr 2014 bzw. der Absenkung des Lehrgerüsts über einen Zeitraum von acht Jahren permanent und stellen damit eine umfassende Grundlage zur Gegenüberstellung von Messung, numerischer Simulation und ingenieurpraktischen Ansätzen auf der Einwirkungs‐ und Widerstandseite dar. Im vorliegenden Beitrag wird die Konstruktion der Brücke einschließlich Herstellungsmethode und Installation der Messtechnik beschrieben. Über den Zeitraum von acht Jahren werden die Messergebnisse in ihrer Gesamtheit sowie auch in einzelnen ausgewählten Detailmessperioden dargestellt und den rechnerisch ermittelten Werten gegenübergestellt. Weiterhin erfolgt auch eine Gegenüberstellung der Ergebnisse der numerischen Simulationen der Betongelenke mit den in situ gemessenen Verformungen und analytisch errechneten Beanspruchungen. Die Ergebnisse über den Messzeitraum zeigen ein sehr träges Temperaturverhalten und sehr geringe Verdrehungen an den Betongelenken. Des Weiteren sind anhand der Messergebnisse zeitabhängige Verformungen des Betons deutlich erkennbar.