bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lactobacillus plantarum S9 alleviates lipid profile, insulin resistance, and inflammation in high-fat diet-induced metabolic syndrome rats
Authors: Zhao Lei , Shen Yunjiao , Wang Yunlong , Wang Lei , Zhang Lin , Zhao Zijian , Li Shengyu 
Published: September 2022

AbstractProbiotics are considered to play an crucial role in the treatment of high-fat diet (HFD)-induced lipid metabolic diseases, including metabolic syndrome (MS). This study aimed to investigate the effects of Lactobacillus plantarum S9 on MS in HFD-fed rats, and to explore the underlying role of probiotics in the treatment of MS. Sprague-Dawley rats were fed with HFD for 8 weeks, followed by the treatment of L. plantarum S9 for 6 weeks, and The body weight and blood glucose level of rats were detected on time. The results showed that L. plantarum S9 significantly decreased the body weight gain, Lee’s index, and liver index. Additionally, L. plantarum S9 reduced the levels of serum lipids and insulin resistance. L. plantarum S9 also decreased the levels of alanine aminotransferase (ALT) and aspartate transaminase (AST) in liver. Moreover, the serum levels of MS-related inflammatory signaling molecules, including lipopolysaccharide (LPS) and tumor necrosis factor-α (TNF-α), were significantly elevated. Western blot analysis showed that L. plantarum S9 inhibited the activation of nuclear factor-κB (NF-κB) pathway, decreased the expression level of Toll-like receptor 4 (TLR4), suppressed the activation of inflammatory signaling pathways, and reduced the expression levels of inflammatory factors in HFD-fed rats. Moreover, it further decreased the ratios of p-IκBα/IκBα, p-p65/NF-κB p65, and p-p38/p38. In summary, L. plantarum S9, as a potential functional strain, prevents or can prevent onset of MS.
A Late Devonian tree lycopsid with large strobili and isotomous roots
Authors: Liu Le , Wang De-Ming , Zhou Yi , Qin Min , Ferguson David K. , Meng Mei-Cen 
Published: September 2022

AbstractTree lycopsids prospered in the Late Devonian and constituted a major part of the Late Paleozoic forest ecosystem that deeply impacted the Earth’s climate. However, the fertile organs of these early tree lycopsids display low morphological disparity, which has hampered further knowledge about their ecological habit. Here, we report Omprelostrobus gigas gen. et sp. nov. from the Upper Devonian (Famennian) Wutong Formation at Changxing, Zhejiang, China. The collection includes aerial axes, strobili and associated roots. The strobili are the largest among coeval lycopsids to our knowledge, and are divided into proximal and distal portions by dimorphic sporophylls with differentiated laminae and probable strong photosynthetic capacity. The associated but not attached roots displaying multiple isotomous branches lack rootlets and typical rootlet scars. The varied strobili sizes of early tree lycopsids were relatively independent of their body plan, but the large strobili could suggest increased reproductive investment to overcome the disadvantages of the disturbed flooded habitat.
Iron-dependent mutualism between Chlorella sorokiniana and Ralstonia pickettii forms the basis for a sustainable bioremediation system
Authors: Rawat Deepak , Sharma Udita , Poria Pankaj , Finlan Arran , Parker Brenda , Sharma Radhey Shyam , Mishra Vandana 
Published: September 2022

Abstract
Phototrophic communities of autotrophic microalgae and heterotrophic bacteria perform complex tasks of nutrient acquisition and tackling environmental stress but remain underexplored as a basis for the bioremediation of emerging pollutants. In industrial monoculture designs, poor iron uptake by microalgae limits their productivity and biotechnological efficacy. Iron supplementation is expensive and ineffective because iron remains insoluble in an aqueous medium and is biologically unavailable. However, microalgae develop complex interkingdom associations with siderophore-producing bacteria that help solubilize iron and increase its bioavailability. Using dye degradation as a model, we combined environmental isolations and synthetic ecology as a workflow to design a simplified microbial community based on iron and carbon exchange. We established a mutualism between the previously non-associated alga Chlorella sorokiniana and siderophore-producing bacterium Ralstonia pickettii. Siderophore-mediated increase in iron bioavailability alleviated Fe stress for algae and increased the reductive iron uptake mechanism and bioremediation potential. In exchange, C. sorokiniana produced galactose, glucose, and mannose as major extracellular monosaccharides, supporting bacterial growth. We propose that extracellular iron reduction by ferrireductase is crucial for azoreductase-mediated dye degradation in microalgae. These results demonstrate that iron bioavailability, often overlooked in cultivation, governs microalgal growth, enzymatic processes, and bioremediation potential. Our results suggest that phototrophic communities with an active association for iron and carbon exchange have the potential to overcome challenges associated with micronutrient availability, while scaling up bioremediation designs.
Bolus Texture Testing as a Clinical Method for Evaluating Food Oral Processing and Choking Risk: A Pilot Study
Authors: Bandini Andrea , Gandhi Pooja , Sutton Danielle , Steele Catriona M. 
Published: September 2022

Purpose:Choking on food is a leading cause of accidental death in several populations, including children, people with intellectual/developmental disability, and older adults in residential care facilities. One contributor to choking risk is incomplete oral processing and failure to convert food to a cohesive, nonsticky bolus with a maximum particle size that will not block the airway. Clinical tests of mastication do not evaluate properties of chewed food boluses. We characterized expectorated boluses, after oral processing, using methods developed by the International Dysphagia Diet Standardisation Initiative (IDDSI).Method:Seventeen adults without dysphagia (seven women and 10 men), aged 23–55 years, chewed samples of a cracker, a raw baby carrot, and a circular, dome-shaped gummy candy. Chewing metrics were obtained up to the point when the person indicated that they were ready to swallow. The bolus was then either expectorated or swallowed; IDDSI tests were used to characterize the expectorated boluses.Results:Measures of chewing did not differ between spit and swallow conditions. Expectorated cracker and carrot boluses had maximum particle size consistent with IDDSI Level SB6 Soft & Bite-Sized foods or lower. The gummy candy samples remained at IDDSI Level RG7 Regular food consistency.Conclusions:This study suggests that expectorated ready-to-swallow boluses are representative of boluses that are swallowed and that oral processing in adults without dysphagia typically results in boluses at IDDSI's Level SB6 or lower. IDDSI's testing methods provide a practical method for evaluating oral processing by characterizing expectorated ready-to-swallow boluses and may guide food texture recommendations for persons who have increased risk of choking.
Liens dans une équipe pluridisciplinaire de pédopsychiatrie
Authors: Tavares Manuel , Billon Juliette , Evellin Isabelle , Die Saez Kristell , Levivier Ana-Paula , Huber Fabienne 
Published: September 2022

Les auteurs rappellent la nécessité, pour un secteur de pédopsychiatrie, d’être constitué d’une équipe pluridisciplinaire, permettant une diversité des approches cliniques, pour mieux tenir compte de la complexité du fonctionnement mental de l’enfant.
Les auteurs insistent sur le besoin de passer d’une clinique de la classification à une clinique de l’accompagnement et de l’engagement de la part du thérapeute, de dépasser le seul modèle médical pour s’élargir à d’autres modèles, contribuant à la mise en place d’une « clinique de situation ».
Dans le Service de pédopsychiatrie du CHU de Reims, l’équipe du Centre-Médico-Psychologique s’est appuyée sur un fonctionnement basé sur un concept dénommé « Direction de Cure ». Il s’agit ici de créer un lien de travail rassemblant l’enfant et sa famille, voire d’autres partenaires, tout au long de la cure pédopsychiatrique, quelle qu’en soit la durée.
Une institution ne pouvant être thérapeutique que si elle développe une certaine cohérence à partir de ses différences, en prenant soin du fonctionnement institutionnel multi-référentiel. Est mis en évidence l’importance d’un réel travail thérapeutique se basant sur le tissage des liens et sur un partage et une intégration des expériences, permettant ainsi l’expression d’une véritable intelligence collective.
Ist die ASV-Therapie eine Überdruck- oder eine Beatmungstherapie?
Ein Vergleich des SBH am Tag und unter ASV
Authors: Barleben André , Allrich Marika , Grüning Wolfram 
Published: September 2022

ZusammenfassungZiel dieser Arbeit war es, festzustellen, ob die Therapie mit einer adaptiven
ServoVentilation (ASV) zu einer Hypokapnie und Alkalose führt. Dazu wurde der
Säure-Basen-Status (SBH) mit Kohlendioxid- und Sauerstoffpartialdruck im arterialisiertem Blut
(pCO2 und pO2), Standartbicarbonat (SBC) und pH am Tag spontan atmend und nachts unter ASV
gemessen. Auslöser dieser Arbeit war u.a. das Ergebnis der SERVE-HF Studie, welche bei
Patienten mit einer Herzinsuffizienz und linksventrikulärer Ejektionsfraktion <45% unter
der ASV ein erhöhtes Mortalitätsrisiko fand. Es gab u.a. die Vermutung eines
Gerätealgorithmus-basierten Effektes. Als möglicher Faktor wurde diskutiert, ob die minimale
Druckunterstützung (PSmin) von 3 cmH2O über eine respiratorische Alkalose einen
pro-arrhytmogenen Effekt hat. Eine Studie von Patienten mit therapie-assoziierter zentraler
Schlafapnoe (treatment emergent central sleep apnea,TECSA) und normaler Herzfunktion verglich
4 ASV-Geräte (J. Knitter et al. Comparison of Performance of Four Adaptive Servo Ventilation
Devices in Patients with Complex Sleep Apnea, Sleep 2018 Vol. 41 Pages A203-A204). Es fand
sich ein signifikant höheres Atemminutenvolumen nur mit dem in der SERVE-HF- Studie
verwendeten Gerät. Somit könnte diese Hyperventilation ein Geräte-und kein Klasseneffekt
sein.
Patienten 226 Patienten, die zur Verlaufskontrolle oder
Neueinstellung der ASV von 10/2018 bis 03/2020 kamen: Alter 65,2±11,3 Jahre, BMI
35,7±7,5kg/m2, Gesamtnutzungsdauer 5530±5400 h, 5,6±2,5 h/d, PSmin 4,9±1,8
cmH2O. Alle Patienten hatten eine regelrechte linksventrikuläre Funktion, der
Großteil hatte die ASV wegen TECSA, selten eine kardiale oder ganz selten eine andere
Genese.
Ergebnisse Bei 29 Patienten(12,8%) fand sich eine Hypokapnie mit
pCO2 morgens < 36 mmHg.
Schlussfolgerung Unter ASV konnten wir bei unseren nichtherzinsuffizienten Patienten eine
geringe, aber nicht signifikante Zunahme des pCO2 feststellen. Immerhin hatten 12,8% eine
Hypokapnie, die in der Hälfte der Fälle so relevant war, dass wir eine Modifikation der
Therapie vornahmen. Dies kann verschiedene Ursachen haben, eindeutige Kriterien konnten nicht
gefunden werden. Aber es besteht die Gefahr einer Hyperventilation, sodass unter ASV ein SBH
erfolgen sollte.
Increased Rate of Spontaneous Pneumothorax in Infants of COVID-19 Positive Mothers
Authors: Gürel Selçuk , Yıldırım Şule 
Published: September 2022

Abstract
Objective The epidemiological and clinical characteristics of neonates born to women infected with coronavirus disease 2019 (COVID-19) during pregnancy were assessed, and the correlation between this infection and spontaneous pneumothorax in neonates born to mothers with COVID-19 was evaluated in the present study.
Methods Records of 14 neonates in the neonatal intensive care unit with pneumothorax were collected and analyzed. Pregnant women were routinely screened for COVID-19 before birth. This study only included the neonates of mothers positive for severe acute respiratory syndrome coronavirus 2 immunoglobulin Mand immunoglobulin G and developing spontaneous pneumothorax. Antenatal, natal and postnatal risk factors, data related to demographic, epidemiological and clinical characteristics, treatment strategies, and breastfeeding history were obtained from medical records.
Results The gestational age of the 14 neonates was 30 to 38 weeks. One male infant was born by normal spontaneous vaginal delivery, while all other infants were born by C-section. Though the mothers did not have a diagnosis of COVID-19 in their charts, they all reported one or more symptoms when interviewed. No mother had received a COVID-19 vaccination before or during pregnancy. No mother had undergone a hospital visit or doctor examination due to suspicion of COVID and COVID polymerase chain reaction test. COVID antibody titers were present during admission to hospital before birth.
Conclusion The infants of pregnant cases with symptomatic or asymptomatic COVID-19 may develop respiratory distress and pneumothorax. Observational data obtained from case series similar to what is presented here may be accepted as a potential first step to producing hypotheses to test with preclinical or clinical models if it can be expanded in larger cohorts.
Real space study of local bonding for zinc structure based on temperature-dependent x-ray pair distribution function analysis
Authors: Masadeh Ahmad S. , Shatnawi Moneeb T. M. , Abu Waar Ziad Y. , Alzoubi Gassem M. , Ren Yang 
Published: September 2022

Zinc metal has a hexagonal close packing hcp structure with an unusual axial ratio c/a. This work presents the local atomic structure analysis of elemental zinc using the x-ray atomic pair distribution function (PDF) method and total synchrotron x-ray scattering in the temperature range of 100–300 K. In this PDF study, we determined the evolution of local bonding in zinc structure in the temperature range of 100–300 K by fitting the first two peaks in the radial distribution function (RDF), R(r), with two Gaussian peaks. Our local structure results reveal a piece of evidence for unusual bond length behavior at low temperatures. The PDF analysis revealed that the a-axis varies linearly from 300 to 160 K and remains constant below 160 K. This local structural result indicates that at temperatures below 160 K, the Zn–Zn bonds are no longer thermally contractible in the ab plane, in agreement with standard crystallographic analysis [J. Nuss et al., Z. Anorg. Allg. Chem. 636, 309 (2010)]. Another significant observation is that the local thermal expansion for the a-axis was found to be three times larger than the one obtained using conventional crystallographic methods [U. Wedig et al., Z. Anorg. Allg. Chem. 639, 2036 (2013)]. This PDF result shows the advantage of total scattering PDF methods in studying the local structural features in elemental zinc, which cannot be captured by the crystallographic model. In addition, this PDF study demonstrates that multiple RDF-peak fitting is a useful approach for interpreting the local structural features of such a non-ideal hcp structure.
Интерпретация авторского символа в литературном тексте и возможность его перевода
Authors: Pejanović Ana 
Published: September 2022

Abstract
The paper aims at the possible interpretation of the author’s symbol and the potential problem of its accurate
translation into Russian. On the notable example of Njegoš’ lyrical poem A Night More Precious than a Century we presented the
specific algorithm of the decoding procedure in deciphering the complex semantics of the author’s symbol, as well as the method of
finding its translation equivalent in the Russian language. The analysis starts from the point of view of modern translatology,
linguistics, and literary studies and adequately takes into account the relevant data of Njegoshology, as an interdisciplinary
science. To elucidate the complex nature of the symbol, as a linguistic sign and its function in the literary text, as well as the
possibility of its translation into Russian, various methods were applied: contrastive, etymological, interpretive analysis in the
synchronic and diachronic plane. The conducted analysis illustrates the fundamental importance of attentively examining symbols
from various aspects, starting from the most elementary linguistic level within the source language, through the literary in the
style of the epoch and the idiostyle of the prominent writer and concluding with the interlingual translatological approach. This
multifaceted interpretation contributes to resolving the semantics of the symbol and finding its translation equivalent.
Translation and Cross-Cultural Adaptation of the “Early Support Monitoring Protocol”
Authors: de Albuquerque Suzana Cinthia Silva Oliveira , Marques Leonardo Brandão , Santana Pinto Ig Ibert Bittencourt , Van der Ley Quintela Júlia Carvalho 
Published: September 2022

Abstract
Parents are required to make various decisions after a child’s hearing loss diagnosis. With that in mind, one of the researchers of this study, the father of a child with deaf, did not find any available instrument in the Brazilian literature to support was found to the decision-making process for parents. Considering the importance of assisting parents, caretakers, and professionals who work with Deaf and Hard of Hearing children to monitor and assess the child’s development, this work aims to translate and adapt a monitoring protocol for professionals and parents. For this, we translated and cross-culturally adapted 452 items of the Early Support instrument. The items corresponded to the domains of communication, attention, listening, and vocalization. We selected 25% of the items to be assessed by specialists, which were divided into the categories: (1) cultural adequacy; (2) concept presented; and (3) target audience adequacy. A reverse translation was conducted in this stage of the research. After compiling the data and correcting the probable translation errors, it was possible to analyze the items that were not included in the specialists’ assessment and propose an assessment with new items. Afterward, the translated items were compared with the reviewed version of the instrument (Success From the Start), which comprises 347 items of the two development domains.
Multi-Layered Civil Society Documentation of Human Rights Violations in Myanmar: The Potential for Accountability and Truth-Telling
Authors: Matelski Maaike , Dijkstra Rachel , McGonigle Leyh Brianne 
Published: September 2022

AbstractSerious human rights violations, particularly against ethnic minorities, have been a stark reality in Myanmar for many decades. The Rohingya crisis that deteriorated in 2017 and the ongoing abuses in areas of armed conflict such as Kachin, Rakhine, and Shan States, and more recently in response to anti-coup protests, demonstrate the recurrence of violence and trauma. During these decades of violence and ongoing violations, civil society initiatives inside and outside the country have attempted to monitor and document human rights abuses in order to contribute towards accountability and truth-telling. Despite the vast array of civil society documentation efforts, this work has sparked limited scholarly debate, especially concerning the complexities of existing multi-layered systems of documentation. This article analyses the current scope of documentation work related to serious human rights violations in Myanmar and the methods, standards, and audiences of various initiatives. We distinguish three layers of civil society documentation: (i) initiatives carried out on the local level in Myanmar and the various border areas; (ii) initiatives carried out by the refugee and diaspora communities; and (iii) third-party initiatives. We then analyse two elements that complicate documentation efforts, namely the risk of ‘over-documentation’, and issues of hierarchy and contestation. These challenges make clear the value of strengthening partnerships and cooperation for all groups involved in documentation work that aims to promote and protect human rights. We end by cautiously considering the potential impact, value, and limitations of Myanmar’s multi-layered documentation efforts for accountability and truth-telling in the aftermath of the 2021 military coup.
Transcranial magnetic stimulation (TMS) seeded tractography provides superior prediction of eloquence compared to anatomic seeded tractography
Authors: Muir Matthew , Prinsloo Sarah , Michener Hayley , Shetty Arya , de Almeida Bastos Dhiego Chaves , Traylor Jeffrey , Ene Chibawanye , Tummala Sudhakar , Kumar Vinodh A , Prabhu Sujit S 
Published: September 2022

Abstract

Background
For patients with brain tumors, maximizing the extent of resection while minimizing postoperative neurological morbidity requires accurate preoperative identification of eloquent structures. Recent studies have provided evidence that anatomy may not always predict eloquence. In this study, we directly compare transcranial magnetic stimulation (TMS) data combined with tractography to traditional anatomic grading criteria for predicting permanent deficits in patients with motor eloquent gliomas.

Methods
We selected a cohort of 42 glioma patients with perirolandic tumors who underwent preoperative TMS mapping with subsequent resection and intraoperative mapping. We collected clinical outcome data from their chart with the primary outcome being new or worsened motor deficit present at 3 month follow up, termed “permanent deficit”. We overlayed the postoperative resection cavity onto the preoperative MRI containing preoperative imaging features.

Results
Almost half of the patients showed TMS positive points significantly displaced from the precentral gyrus, indicating tumor induced neuroplasticity. In multivariate regression, resection of TMS points was significantly predictive of permanent deficits while the resection of the precentral gyrus was not. TMS tractography showed significantly greater predictive value for permanent deficits compared to anatomic tractography, regardless of the fractional anisotropic (FA) threshold. For the best performing FA threshold of each modality, TMS tractography provided both higher positive and negative predictive value for identifying true nonresectable, eloquent cortical and subcortical structures.

Conclusion
TMS has emerged as a preoperative mapping modality capable of capturing tumor induced plastic reorganization, challenging traditional presurgical imaging modalities.