bluuebunny/crossref_metadata_2025_split huggingface dataset:
Artificial Urinary Sphincter Is Better Than Slings for Moderate Male Stress Urinary Incontinence With Acceptable Complication Rate: A Systematic Review and Meta-Analysis
Authors: Lin Lede , Sun Wenjin , Guo Xiaotong , Zhou Liang 
Published: February 2022

BackgroundThis meta-analysis aimed to compare the efficacy of artificial urinary sphincter (AUS) and slings for the treatment of moderate male stress urinary incontinence (SUI) based on existing data.MethodsThe study was in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis. We searched the widely acknowledged database including PubMed, Embase (Ovid version), Medline (Ovid version), and Cochrane Central Register of Controlled Trials (till February 2021). Male patients with moderate SUI who underwent AUS or slings procedure over 18 years old and had been monitored with a mean follow-up time of at least 12 months were included. The primary outcome was success rate defined as daily pad use with 0–1 pad/d postoperatively. Articles with congruent outcomes were suitable for inclusion. The secondary outcome included complication rate of infection, erosion, acute urinary retention, and surgical revision.ResultsFive studies with a total of 509 patients (295 for slings and 214 for AUS) were recruited. The success rate was higher in AUS with an odds ratio (OR) = 0.57 (95% CI: 0.36–0.90). As for the overall complication rate, no significant difference was discovered between slings and AUS groups (OR = 1.06, 95% CI: 0.58–1.92, P = 0.86).ConclusionTo conclude, AUS was better than slings for moderate male SUI treatment according to daily pad use with an acceptable complication rate. The slings also had clinical value and were options when aging male patients were AUS naive and refused inserted mechanical devices. High-quality pieces of evidence are needed to confirm the efficacy of AUS and slings in moderate male SUI.Systematic Review Registration:https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=271203, identifier: CRD42021271203.
Extinção
Authors: Arantes Paulo Eduardo 
Published: February 2022

Os escritos reunidos em Extinção constituem uma crítica radical, sem subterfúgios e sem concessões, “impiedosa” – como a definiu certa vez o jovem Marx – do mundo da cruel “máquina capitalista de moer”, do estado de sítio permanente. Paulo Arantes se define como frankfurtiano de esquerda, (...) poderíamos também defini-lo como marxista ilegal, em oposição aos marxistas legais brasileiros, cuja longa marcha pelas instituições culminou na “fusão da intelectualidade tucana com as altas finanças”. Neste livro ele analisa, como ensina Brecht, não o bom antigo, mas as novidades ruins. Entre estas, elementos que de certa forma dão unidade ao processo imperialista atual: o retorno à Acumulação Primitiva, a reconquista colonial do mundo, a realização das formas supostamente arcaicas de exploração e dominação. Diante do “matadouro das limpezas sociais” que encontramos em um país como o Brasil, como organizar a resistência dos oprimidos? Tarefa mais difícil hoje, quando o partido que supostamente os representava conheceu “a pior das capitulações: sem combate e por adesão prévia ao programa do inimigo”. Este livro, tônico e irônico é um salutar antídoto “idiotia triunfante e bem pensante” do novo Febeapá.
(Extraído da orelha de Michel Löwy para a edição da Boitempo)
Palavras-chave: Acumulação primitiva, Anos Lula, Arturo Ui, Brecht, Capitalismo de acesso, Cultura do excesso, Danilo Zolo, David Harvey, Era tucana, Errol Morris, Estado de sítio, Fukuyama, Guerra cosmopolita, Guerra do Iraque, McNamara, O novo imperialismo, PCC, Trabalho da guerra.
Vacuum aspiration in the complex treatment of patients with destructive forms of erysipelas
Authors: Vasylevska L. A. 
Published: February 2022

The purpose of the study. is to give a clinical evaluation of the effectiveness of vacuum therapy in combination with autodermoplasty in the complex treatment of patients with necrotic erysipelas.
Materials and methods of research. 114 case histories of patients who were hospitalized in the center of purulentseptic surgery in the Non profit municipal enterprise «City Hospital № 3» in Zaporizhzhia for the period 2019–2020 were analyzed retrospectively and prospectively.
Results. Patients on admission to the clinic underwent surgical treatment, which consisted in opening a purulent lesion, necrectomy. After installation of the vacuum aspirator the general condition and the general state of health of patients considerably improved, already by the 5th day cleaning of a wound and emergence of granulation had been noted. The use of a vacuum device contributed to the dosed pressing of the skin flap to the wound surface, reliable fixation of the skin flap and to some extent – the improvement of local microcirculation.
Conclusions. The use of vacuum therapy helps to clean the purulent wound, reduces the first phase of the wound process and potentiates the filling of the wound surface with mature granulation tissue. The use of vacuum therapy provides reliable fixation of skin grafts on the wound surface, eliminates the risk of their displacement in the near future after autodermoplasty
Effect of additional strengthening of colonic anastomosis on abdominal contamination severity
Authors: Mylytsia M. M. , Mylytsia К. M. , Steblianko V. V. , Soldusova V. V. , Kazakov V. S. 
Published: February 2022

Purpose of the study. To investigate the effect of additional strengthening of the colonic anastomosis (CA) using modern adhesive materials on the severity of abdominal contamination in patients with insulin resistance (IR).
Materials and methods. The study involved 80 patients with IR, who underwent surgery with the CA imposition (median age of the patients – 64 (57; 71) years). All patients were divided into 2 groups, depending on the method of strengthening the CA suture: 1 group – 40 patients who underwent the application of a onerow continuous suture (OCS) of the CA (median age of patients – 65 (57; 75) years, 2 group – 40 patients to whom OCS CA was applied, and in order to seal and strengthen the anastomosis zone a modern Nbutylcyanoacrylate tissue adhesive was added (median age of patients – 63,5 (58,5; 70,5) years. The spectrum of microbial flora of secretions from drains near the anastomosis was determined.
Results. The additional use of modern Nbutylcyanoacrylate tissue adhesive to strengthen the area of CA with the imposition of a OCS in patients with IR contributes to a reliable reduction of number of patients with associations consisting of two types of microorganisms compared to the patients without additional strengthening (2 (5,0%) versus 9 (22,5%) of patients, respectively) (χ2 = 5,17, df = 1; р < 0,05), the greater number of patients with no growth of microorganisms in crops from the anastomotic zone ((11 (27,5%) of patients versus 3 (7, 5%) of patients, respectively), as well as fewer cases of high degree of anastomosis zone contamination (3,48 times (χ2 = 7,68, df = 1; р < 0,05)), with prevalence of mild contamination (3, 35 times (χ2 = 15,24, df = 1; р < 0,05)).
Conclusion. The additional use of modern Nbutylcyanoacrylate tissue adhesive to strengthen the area of CA with the imposition of a onerow continuous suture in patients with IR contributes to a reliable reduction of contamination of the area around the anastomosis compared to the patients without additional strengthening.
Diagnostic capabilities of magnetic resonance imaging in assessing the state of the large and small intestines
Authors: Sementsov O. S. , Ponomarenko V. V. 
Published: February 2022

Purpose of the study. Purpose of the work is to show the possibilities of radiation diagnosis of the normal anatomy of the small and large intestine, as well as their pathological changes through the use of MRI (Hydro-MRI).
Materials nad methods. Thirty patients were examined by the method of Hydro-MRI. All patients underwent magnetic resonance imaging on a device with a magnetic induction of 1,5 T. To carry out Hydro-MRI, we used T2-weighted sequences, such as a one-time fast spin echo signal obtained in several planes, STIR sequences in three mutually perpendicular sequences, so that edema wall edema can be estimated with additional diffusion-weighted images.
Results. Twentypatientswiththemanifestations of Crohn's disease in the form of terminal ileitis, presence of interlope fistulous passages, paraproctitis (fistulous form) were detected. Colon tumors were detected in 8 patients, recurrence of gastrointestinal stromal tumor (GIST) of the small intestine in the anastomosis zone was detected in one patient, and no pathological changes were detected in one patient.
Conclusion. Hydro-MRI allows visualizing the mass of the small, large intestine and determining the degree of invasion of the intestinal wall and surrounding tissues. Enterography using magnetic resonance enterography has become the most effective methods for visualizing the small intestine in patients with Crohn's disease and can visualize inflammation of the intramural or proximal small intestine in about 50% of patients with Crohn's disease who have undergone endoscopically normal studies. Hydro-MRI is indicated for Crohn's disease and for determining the degree of inflammatory activity. Recent evidence suggests that cross-section visualization may be useful in determining response to therapy, assessing bowel healing and monitoring disease progression. Also, according to researchers at the Medical Imaging Center, University College London, the quantitative motility of the small intestine is an objective biomarker of endoscopic and histopathological inflammatory activity in Crohn's disease and is comparable to previously confirmed estimates of MRI activity enhanced by gadolinium. The final ileal mobility indicator showed a good correlation with endoscopic and histopathological activity in Crohn's disease. The study is painless, no radiation load. Hydro-MRI is a method of choice, when it is impossible to conduct an X-ray examination of the intestine, the inability/ uninformativeness of an endoscopic examination of the small, large intestine. Along with video capsular endoscopy, it allows visualization of all departments of the small and large intestine.
Microbiological landscape of pyogenic liver abscesses
Authors: Novak V. V. , Yareshko V. G. , Shapoval S. D. 
Published: February 2022

Purpose of the study. To study the features of the microbial landscape of AP at different stages of their formation.
Materials and methods. The results of examination and treatment of 80 patients with pyogenic liver abscesses for the period 2019–2020 were analyzed. The average age of patients was 48,4 ± 4,7 years. The duration of the disease at the time of hospitalization averaged 10,2 ± 3,4 days. The condition of all patients was assessed as moderate and severe, hospitalization was carried out on urgent indications. The inclusion criterion was the presence of pyogenic liver abscesses, the exclusion criteria were cholangiogenic and specific abscesses. Microbiological studies of the species composition of pathogens and their sensitivity to antibiotics were performed in all patients during surgery and in the dynamics of the postoperative period.
Results. The microbial landscape of pyogenic abscesses in their different stages of formation differed both in quantitative and qualitative ratio. Seeding of aerobic monoinfection from purulent foci in stage I was predominant (P <0,05) and amounted to 69,4%. In this case, the aerobic gramnegative (gram (-)) flora of the foci of infection prevailed over the gram-positive (gram (+)). In stage III, the number of microbial associations sown from the purulent cell increased from 26,6 to 36,6% (P < 0,05). The increase was due to the sowing of aerobic associations. The main share among gram (-) aerobes was E. coli and Klebsiella pneumoniae, and the main representative of the mixed aerobic infection was St. auerus (including MRSA strains). In stage IV formation of pyogenic liver abscesses, the number of microbial associations sown from the purulent cell did not differ from the sowing of monoinfection (P > 0,05). There have been cases of seeding of facultative anaerobes of the genus Peptostreptococcacea and facultative anaerobic bacteria of the genus Clostridium.
Conclusion. Carrying out of adequate combined ABT to patients with AP according to the developed algorithms, allowed to reduce terms of recovery of patients: for 3–4 days normalization of body temperature (t = 5,66176; P <0,000001) and a leukocyte formula (t = 8,56860; P < 0,000001) in patients of the main group compared with control patients. In turn, this contributed to a probable reduction in the length of stay of patients in the hospital for 3 days (t = 3,95561; P = 0,000116).
From secretory otitis to retraction cholesteatoma
Authors: Kokorkin D. M. , Skorobogaty V. V. , Gusakova O. O. , Shevlyuk P. P. , Kolyada N. A. 
Published: February 2022

Based on the preliminary examination and further treatment of 980 children, the most influential consequences of secretory otitis were identified and the means of their prevention were proposed. Based on the results of long-term observation, conclusions were drawn. Chronic secretory otitis develops in 16% of children with recurrent secretory otitis, in 25% of cases the disease becomes malignant, and in 10% of cases goes into the stage of chronic purulent otitis media. In the treatment of recurrent and complicated chronic secretory otitis, it is advisable to follow the sequence of treatment, because 68% of children show existing or hidden signs of sinusitis, which requires prior surgical treatment. Among the detected forms, polyposis sinusitis with deformation of the nasal septum predominates (88,5%).
The presence of retraction cholesteatoma with a predominant distribution within the tympanic cavity, limited defects of the chain of auditory ossicles and wide possibilities of their replacement, delayed cholesteatoma process with atrophy of matrix structures create conditions for organ-sparing surgery which corresponds to closed tympanoplasty. The morphological and functional effect of such operations can reach 91,5 ± 1,7% of cases in the group of children and adolescents and 88,2 ± 2,1% of observations in the group of adult patients, while the snail reserve decreased by 10,9 ± 3,3 dB in the group of children and 28,4 ± 3,3 dB in the group of adult patients.
Unilateral spinal anesthesia and the sciatic nerve block in foot surgery
Authors: Gritsenko S. N. , Shapoval S. D. , Filimonov R. V. 
Published: February 2022

Purpose of the study. To evaluate the effectiveness of unilateral spinal anesthesia as a method of pain relief during foot surgery. Analyze the effectiveness of unilateral spinal anesthesia versus sciatic nerve block. To develop an algorithm for performing unilateral spinal anesthesia during foot surgery.
Materials and methods. We examined 64 patients who were treated in the department of purulent surgery of the 3rd city hospital in Zaporozhye with a diagnosis of diabetic foot syndrome in the period from 2017 to 2019.
Research methods. Assessment of the level of pain intensity using the standard visual analogue scale and the concentration of glucose in the blood serum. Monitoring of the parameters of the cardiovascular system, the temperature of the skin of the lower leg during anesthesia, Doppler scanning of the peripheral circulation in the foot.
Results. 4 hours after performing anesthesia, the intensity of pain during movement of the lower limb, according to the visual analogue scale in the group with unilateral spinal anesthesia was 2,3 times less than in the group with sciatic nerve block (p < 0,05). After 10 hours – in the sciatic nerve block group there was a 9,4% increase in comparison with the unilateral spinal anesthesia group (p < 0,05). Compared with the unilateral spinal anesthesia group, in the sciatic nerve block group 20 minutes after anesthesia, the heart rate decreased by 7,2% (p < 0,05). After unilateral spinal anesthesia, the level of systolic blood pressure on 1 toe of the foot increased by 18,3% 20 minutes after anesthesia, and 20 minutes after sciatic nerve block – by 13,7% (p < 0,05). In patients with the unilateral spinal anesthesia group, the temperature on the operated lower limb after anesthesia increased by 3,8%, in the sciatic nerve block group – by 2,8% (p < 0,05).
Conclusions. Regional anesthesia is the main method of choice for foot surgery compared to general anesthesia. sciatic nerve block does not in all cases lead to 100% surgical anesthesia and requires additional medical analgosedation. For foot surgery, unilateral spinal anesthesia is preferred.
The absorptive and metabolic features of phagocytosis in children, depending on the frequency of acute respiratory infections
Authors: Ovcharenko L. S. , Tymoshyna O. V. , Vertehel A. O. , Andrienko T. G. , Samokhin I. V. , Kryazhev O. V. , Chakmazova O. M. 
Published: February 2022

Purpose of the study. To improve of innate immune disorders diagnosis in preschool children with respiratory tract recurrent infectious diseases on the basis of new data of phagocytosis parameters by studying its absorption and prooxidant characteristics.
Materials and methods. Under observation were 60 children aged 2 to 5 years. Two groups were formed: 1). children with respiratory tract acute infectious more than 6 times in year (n = 30); 2). children with respiratory tract acute infectious 6 or less times in year (n = 30).
Results. Among children in 1 group, statistically significantly increased the registration quantity of low phagocytic counts (by 60,0%, p < 0,05), phagocytic index (by 56,0%, p < 0,05), index of phagocytosis completeness (70,0%, p < 0,05), neutrophil phagocytic activity stimulated by staphylococcus (50,0%, p < 0,05) and high rates of spontaneous neutrophil phagocytic activity (43,3%, p < 0,05), high serum levels of lipid hydroperoxides (by 80,0%, p < 0,05), diene conjugates (by 80,0%, p < 0,05), malonic dialdehyde (76,7%, p < 0.05), diene ketones (76,7%, p < 0,05), Schiff bases (76,7%, p < 0,05).
Conclusion. In children 2–5 years with respiratory tract acute infectious more than 6 times in year the phagocytic dysfunction and increased lipid peroxidation were established. It is characterizing the failure and slowness of the early immune response.
Inclusion of Cell Technologies in the Protocol of Immunosuppression in Liver Transplantation
Authors: Коротков С.В. , Носик А.В. , Примакова Е.А. , Петровская Е.Г. , Назарова Е.А. , Дедюля Н.И. , Ефимов Д.Ю. , Пикиреня И.И. , Щерба А.Е. , Кривенко С.И. , Руммо О.О. 
Published: February 2022

Современная иммуносупрессивная терапия обеспечивает хорошую долгосрочную выживаемость трансплантатов печени и пациентов после операции. Тем не менее, прием иммуносупрессантов сопряжен с развитием побочных эффектов - почечного повреждения, метаболического синдрома, инфекционных осложнений и повышения риска развития онкологических заболеваний. Альтернативой стандартной иммуносупрессивной терапии являются клеточные биотехнологии, позволяющие замещать иммуносупрессивный эффект протокольной иммуносупрессии без риска развития отторжения. В данной публикации продемонстрированы основные результаты экспериментальных и клинических исследований по изучению применения мезенхимальных стволовых клеток в трансплантации солидных органов. Применение мезенхимальных стволовых клеток жировой ткани на базе Минского научно-практического центра хирургии, трансплантологии и гематологии у пациентов после трансплантации печени сострым почечным повреждением позволило редуцировать дозу базового иммуносупрессанта такролимуса без риска развития отторжения и способствовало быстрому восстановлению почечной функции. На основании проведенного анализа сделаны выводы о целесообразности разработки методов лечения пациентов после органных трансплантаций.
Modern immunosuppressive therapy provides good long-term survival of liver transplants and patients after surgery. Nevertheless, immunosuppression is associated with development of adverse effects - kidney injury, metabolic syndrome, infectious complications, and increase of the risk of cancer. Cell biotechnologies are an alternative to the standard immunosuppressive therapy, which lets to replace the immunosuppressive effect of protocol immunosuppression without the risk of rejection. This publication demonstrates the main results of experimental and clinical studies of application of mesenchymal stem cells in solid organ transplantation. Application of mesenchymal stem cells of adipose tissue at the Minsk Scientific-Practical Center for Surgery, Transplantology and Hematology in patients after liver transplantation with acute kidney injury allowed to reduce the dose of the basic immunosuppressant tacrolimus without the risk of rejection and promoted rapid renal function recovery. On the base of analysis, the conclusions were made about the advisability of development of the methods for treatment of patients after organ transplantation with MSCs.
Prenatal Diagnosis of Apert Syndrome
Authors: Лазаревич А.А. , Венчикова Н.А. , Мараховская Э.И. 
Published: February 2022

Цель исследования. Описать ультразвуковые и патоморфологические признаки синдрома Апера у плода. Материалы и методы. Сонография проводилась на аппарате Voluson 730 Expert с использованием трансабдоминального (4-8 МГц) датчика. Нозологический диагноз установлен по результатам патоморфологического исследования. Результаты. Основными ультразвуковыми (УЗ) признаками синдрома Апера в 19 недель 3 дня явились расширение боковых желудочков головного мозга, деформация черепа и синдактилия II-V кистей. Выводы. Несмотря на узнаваемый симптомокомплекс синдрома Апера, представленные наблюдения подтверждают сложность УЗ-диагностики данной патологии во втором триместре беременности. При УЗ-визуализации синдактилии кистей у плода необходимо провести исследование головного мозга для поиска возможных дополнительных маркеров краниосиностоза в виде деформации черепа, расширения и (или) атипичной формы боковых желудочков, агенезии (дисгенезии) мозолистого тела.
Purpose. To explore the ultrasound and pathomorphological signs of Apert syndrome in the fetus. Materials and methods. Sonography was performed on a Voluson 730 Expert using a transabdominal (4-8 MHz) sensor. The nosological diagnosis is established by the result of pathomorphological and histological studies. Results. We present sporadic case of Apert syndrome in the fetus of the second trimester. The ultrasound (US) signs were expansion of the lateral ventricles of the brain, deformation of the skull and syndactyly of II-V hands. The diagnosis was established by pathomorphological expertise. Conclusions. Apert syndrome characterized by a unique set abnormalities, but it is difficult to determine prenatal diagnosis in second trimester. With ultrasound imaging of fetal hand syndactyly, it is necessary to study of the brain to search for possible additional markers of craniosynostosis: deformation of the skull, expansion and/or atypical shape of the lateral ventricles, agenesis (dysgenesis) of the corpus callosum.
Enzymatic Activity of the Oral Fluid in Patients with Chronic Recurrent Aphthous Stomatitis and Diseases of the Gastrointestinal Tract in the Dynamic of Treatment
Authors: Кулиева Л.Х. 
Published: February 2022

Проблема комплексного подхода к лечению хронического рецидивирующего афтозного стоматита и выработки эффективной терапии остается актуальной и важной в стоматологии. Хронический рецидивирующий афтозный стоматит встречается наиболее часто среди всех заболеваний слизистой оболочки полости рта. Диагностика хронического рецидивирующего афтозного стоматита основывается на оценке клинических и лабораторных данных.
The problem of an integrated approach to the treatment of chronic recurrent aphthous stomatitis and the development of effective therapy remains relevant and important in dentistry. Chronic recurrent aphthous stomatitis occurs most often among all diseases of the oral mucosa. Diagnosis of chronic recurrent aphthous stomatitis is based on clinical and laboratory evaluation.