bluuebunny/crossref_metadata_2025_split huggingface dataset:
Maximizing the efficiency of resistance training
Authors: Pawlina Mateusz , Ziętara Karolina , Raksa Karolina , Nowakowska Katarzyna , Lewkowicz Martyna 
Published: May 2022

Introduction and objective: Resistance training is the main intervention that can develop an individual’s strength and muscle mass. When executed regularly, it provides significant health benefits. The aim of this study is to analyze the current level of knowledge on maximizing the efficiency of resistance training in the context of muscle hypertrophy and increase in muscle strength.
Materials and methods: PubMed and Google Scholar databases were searched. The criteria for qualifying the article for the review were the following keywords: hypertrophy, resistance training, muscle strength, and efficiency. 10 articles from 2017 to 2022 were analyzed.
Description of the state of knowledge: To optimize the way of performing RT, its assumptions should be individually adapted to the exercising person. In the conventional model of muscle hypertrophy, three main factors are distinguished: muscle tension, metabolic stress, and muscle damage. Maintaining greater mechanical muscle tension during training primarily promotes an increase in its strength while increasing metabolic stress is responsible for the intensification of hypertrophy. In terms of hypertrophy, it has been observed that more series of exercises per week means greater gains in muscle mass. Multi-joint exercises involve more muscle mass than single-joint exercises.
Summary: To control the effectiveness of training 1RM should be measured before and after the training cycle. Performing exercises with a high load (RM ≤7) may be the most effective training method for people with limited time resources. To maximize the efficiency of training, only multi-joint exercises may be used.
Key words: hypertrophy; resistance training; muscle strength; efficiency
notes sobre les relacions de poder entre la literatura i la universitat
Authors: Besora i Mascarella Max 
Published: May 2022

Aquest article pretén demostrar que les novel·les de campus funcionen com un element antihegemònic respecte a la institució universitària. L’aparició del primer sistema d’educació racional a favor de la raó i contra el mite, l’Acadèmia de Plató, també comportava l’emergència del seu antagonista, les ficcions acadèmiques, a favor del mite i contra la raó dels filòsofs. Sota el concepte foucaultià del poder-saber, es traçaran les relacions entre la novel·la satírica Giles Goat-Boy, de John Barth, i la vida universitària, cosa que, necessàriament, ens portarà a qüestions com el concepte de veritat en l’educació superior.
Paraules clau: universitat, poder, ficció acadèmica, John Barth, educació.
Tecnologías del biopoder y encrucijadas filosóficas de la resistencia
Authors: Amorós Hernández Miquel 
Published: May 2022

En este artículo se aborda la noción de biopoder de Foucault y se deriva hacia el concepto «biotecnopoder». Este poder en manos de las compañías biotecnológicas se fundamenta en el interés económico de explotación de la información contenida en el ADN y su paso al código binario para el tratamiento bioinformático. El hecho de que todos los seres vivos tengan inscrita su información genética en la misma molécula de ADN permite la manipulación y la inserción de fragmentos de genoma, lo cual puede tomar una deriva totalitaria neoliberal. La solución filosófica es el cuidado de sí y de los demás.
Palabras clave: biopoder, biotecnopoder, bioinformática, tecnologías del ADN, explotación.
Variation in Glucose-6-Phosphate Dehydrogenase activity following acute malaria
Authors: Ley Benedikt , Alam Mohammad Shafiul , Satyagraha Ari Winasti , Phru Ching Swe , Thriemer Kamala , Tadesse Dagimawie , Shibiru Tamiru , Hailu Asrat , Kibria Mohammad Golam , Hossain Mohammad Sharif , Rahmat Hisni , Poespoprodjo Jeanne R. , Khan Wasif Ali , Simpson Julie A. , Price Ric N. 
Published: May 2022

Primaquine and tafenoquine are the only licensed drugs with activity against Plasmodium vivax hypnozoites but cause haemolysis in patients with glucose–6–phosphate dehydrogenase (G6PD) deficiency. Malaria also causes haemolysis, leading to the replacement of older erythrocytes with low G6PD activity by reticulocytes and young erythrocytes with higher activity. Aim of this study was to assess the impact of acute malaria on G6PD activity. Selected patients with uncomplicated malaria were recruited in Bangladesh (n = 87), Indonesia (n = 75), and Ethiopia (n = 173); G6PD activity was measured at the initial presentation with malaria and a median of 176 days later (range 140 to 998) in the absence of malaria. Among selected participants (deficient participants preferentially enrolled in Bangladesh but not at other sites) G6PD activity fell between malaria and follow up by 79.1% (95%CI: 40.4 to 117.8) in 6 participants classified as deficient (<30% activity), 43.7% (95%CI: 34.2 to 53.1) in 39 individuals with intermediate activity (30% to <70%), and by 4.5% (95%CI: 1.4 to 7.6) in 290 G6PD normal (≥70%) participants. In Bangladesh and Indonesia G6PD activity was significantly higher during acute malaria than when the same individuals were retested during follow up (40.9% (95%CI: 33.4–48.1) and 7.4% (95%CI: 0.2 to 14.6) respectively), whereas in Ethiopia G6PD activity was 3.6% (95%CI: -1.0 to -6.1) lower during acute malaria. The change in G6PD activity was apparent in patients presenting with either P. vivax or P. falciparum infection. Overall, 66.7% (4/6) severely deficient participants and 87.2% (34/39) with intermediate deficiency had normal activities when presenting with malaria.
These findings suggest that G6PD activity rises significantly and at clinically relevant levels during acute malaria. Prospective case-control studies are warranted to confirm the degree to which the predicted population attributable risks of drug induced haemolysis is lower than would be predicted from cross sectional surveys.
Patient safety improvement with the patient engagement in Iran: A best practice implementation project
Authors: Ahmadi Sajjad , Haghgoshayie Elaheh , Arjmand Allahveirdy , Hajebrahimi Sakineh , Hasanpoor Edris 
Published: May 2022

Background
Patient engagement in patient safety is aimed at increasing the awareness and participation of patients in error-prevention strategies. The aim of this project was to improve the patient safety with the patient engagement within the local context of a maternity hospital by implementing best practice.

Methods
A clinical audit was conducted using the JBI Practical Application of Clinical Evidence System tool. The current project was conducted in surgical ward of Shahid-Beheshti maternity hospital, Iran. The sample size was 46 patients and 46 healthcare practitioners for both the baseline and follow-up. In phase 1, four audit criteria were used and a baseline audit was conducted for this project. In phase 2, barriers to compliance were identified, and strategies were adopted to promote best practice. In phase 3, a follow-up audit was conducted.

Results
The results showed varying levels of compliance with the four criteria used in this project. The criterion 1, which was related to training of healthcare practitioners on how they can support patients, has the highest compliance at 87% in baseline and follow up data collection. Furthermore, compared with the baseline data (criterion 2 = 52%; criterion 3 = 37%; criterion 4 = 61%), compliance with criteria 2, 3, and 4 notably improved at 85, 76, and 92%, respectively.

Conclusions
The present project successfully implements patient engagement in Iran and reveals varying results on compliance and the increasing knowledge of healthcare practitioners and patients on evidence-based patient engagement in order to improve the patient safety. The used strategies can facilitate implementation of evidence based procedures in clinical practice.
Sunproofed study protocol: A mixed-methods scoping study of sun safety policies in primary schools in Wales
Authors: Peconi Julie , O’Neill Claire , Fegan Greg , Lanyon Kirsty , Driscoll Timothy , Akbari Ashley , Watkins Alan , Abbott Rachel 
Published: May 2022

Background
Skin cancer, including melanoma and non-melanoma (keratinocyte), is increasing in incidence in the UK. Accounting for half of all cancers in England and Wales, the disease significantly impacts overstretched dermatology services. Research suggests that 86% of melanoma is preventable with modified sun exposure. Educating children about sun safety in schools can help prevent skin cancer and is recommended by major health organisations. In England, teaching sun safety in primary schools is compulsory, while in Wales this is left to school discretion.

Aims
Understand how primary schools in Wales are responding to growing skin cancer rates and explore the effectiveness of sun safety policies in schools on knowledge and behaviour.

Methods
Sunproofed is a mixed-methods scoping study comprising 5 work packages (WP) using survey and routine electronic health record (EHR) data supplemented by qualitative case studies. Objective(s) are to: WP1: Discover if primary schools in Wales have sun safety policies; policy characteristics; determine factors that may influence their presence and identify areas where schools need support. WP2: Determine what EHR data is available regarding the incidence of sunburn in primary school children and the feasibility of using this data to evaluate the impact of sun safety policies. WP3: Understand the impact of sun safety policies on sun-safe knowledge and behaviour amongst children, parents, teachers, and school management; identify barriers and facilitators to schools implementing sun safety policies. WP4: Co-produce guidance regarding sun safety policies and best methods for implementation in schools. WP5: Disseminate guidance and findings widely to ensure impact and uptake.

Discussion
Skin cancer rates are increasing in the UK, straining limited resources. Sunproofed has the potential to inform the development of future prevention activities, both in Wales and beyond. This could reduce the number of skin cancer cases in the future and keep people healthier for longer.
Iran and the Deccan: Persianate Art, Culture, and Talent in Circulation, Ed. Keelan Overton (2020)
Authors: Parodi Laura E. 
Published: May 2022

Review of: Iran and the Deccan: Persianate Art, Culture, and Talent in Circulation, Ed. Keelan Overton (2020)
Bloomington: Indiana University Press, 468 pp., 144 colour illus.,
ISBN: 9780253048912, $36.00 (paperback)

The Architecture of a Deccan Sultanate: Courtly Practice and Royal Authority in Late Medieval India, Pushkar Sohoni (2018; 2021)
London and New York: I. B. Tauris, 2018, 320 pp., 121 b&w illus., ISBN: 9781784537944, £28.99 (hardback)
London, Oxford, New York, New Delhi and Sydney: Bloomsbury, 2021, ISBN: 9780755606795, £28.99 (paperback)
FOREIGN EXPERIENCE IN ORGANIZING ORTHODOX MERCY SERVICES IN THE ALTAI KRAI AND THE REPUBLIC OF KAZAKHSTAN: INTERNET RESOURCE ANALYSIS
Authors: Antonovich Irina V. , Kalinina Yulia A. , Chudova Svetlana G. 
Published: May 2022

The article analyzes the activities of the Orthodox services of mercy in two countries, Russia (on the example of the Altai Territory) and the Republic of Kazakhstan. Of particular importance at present is volunteering, which has an impact on the spiritual values of society. In this regard, the study of those social institutions and forms of charity, volunteerism that have been engaged in it for a long time is of particular relevance. Such institutions are communities of sisters of mercy. The article discusses in detail the main directions of the organization of Orthodox services of mercy in the Altai Territory and the Republic of Kazakhstan. To identify the main directions of the organization of Orthodox services of mercy in these subjects, a content analysis of Internet resources was carried out. Analysis of the results of the study revealed that the sisterhood and brotherhood of mercy, the humanitarian National Societies of the Red Cross and Red Crescent coordinate and assist in the work of church social initiatives in the Altai Territory and Kazakhstan. Mercy services are actively developing, effective methods of helping those in need have been developed and implemented.
Faire du terrain dans une formation universitaire de sociologie : jeux de rôle d’étudiants en observation
Authors: Chartier Marie 
Published: May 2022

Cet article revient sur la manière dont les étudiants inscrits en deuxième année de sociologie vivent l’expérimentation de l’observation dans le cadre des travaux dirigés (TD) d’enquête proposés dans une université française. Ce vécu est analysé au prisme de leur condition étudiante : s’intéresser au fonctionnement des enseignements à l’université et au parcours des étudiants de licence 2 de sociologie permet de mettre au jour plusieurs types de tensions à l’œuvre dans l’expérience que font les étudiants de ces TD. Ces tensions se traduisent par différents jeux de rôles qui témoignent d’une pluralité d’appropriations de l’exercice d’observation.
CXCL10 is a novel anti‐angiogenic factor downstream of p53 in cardiomyocytes
Authors: Wahyuni Tri , Tanaka Shota , Igarashi Ryuta , Miyake Yoshiaki , Yamamoto Ayaha , Mori Shota , Kametani Yusuke , Tomimatsu Masashi , Suzuki Shota , Yokota Kosei , Okada Yoshiaki , Maeda Makiko , Obana Masanori , Fujio Yasushi 
Published: May 2022

AbstractTumor suppressor protein p53 plays crucial roles in the onset of heart failure. p53 activation results in cardiac dysfunction, at least partially by suppressing angiogenesis. Though p53 has been reported to reduce VEGF production by inhibiting hypoxia‐inducible factor, the anti‐angiogenic property of p53 remains to be fully elucidated in cardiomyocytes. To explore the molecular signals downstream of p53 that regulate vascular function, especially under normoxic conditions, DNA microarray was performed using p53‐overexpressing rat neonatal cardiomyocytes. Among genes induced by more than 2‐fold, we focused on CXCL10, an anti‐angiogenic chemokine. Real‐time PCR revealed that p53 upregulated the CXCL10 expression as well as p21, a well‐known downstream target of p53. Since p53 is known to be activated by doxorubicin (Doxo), we examined the effects of Doxo on the expression of CXCL10 and found that Doxo enhanced the CXCL10 expression, accompanied by p53 induction. Importantly, Doxo‐induced CXCL10 was abrogated by siRNA knockdown of p53, indicating that p53 activation is necessary for Doxo‐induced CXCL10. Next, we examined the effect of hypoxic condition on p53‐mediated induction of CXCL10. Interestingly, CXCL10 was induced by hypoxia and its induction was potentiated by the overexpression of p53. Finally, the conditioned media from cultured cardiomyocytes expressing p53 decreased the tube formation of endothelial cells compared with control, analyzed by angiogenesis assay. However, the inhibition of CXCR3, the receptor of CXCL10, restored the tube formation. These data indicate that CXCL10 is a novel anti‐angiogenic factor downstream of p53 in cardiomyocytes and could contribute to the suppression of vascular function by p53.
Synthesis of novel triiodide ionic liquid based on quaternary ammonium cation and its use as a solvent reagent under mild and solvent-free conditions
Authors: Sakhdari Mahnaz , Koukabi Nadiya , Zolfigol Mohammad Ali 
Published: May 2022

Abstract
In this article, for the first time, N,N,N-triethyl-3-iodopropan-1-aminium triiodide [N2223I] [I3] was synthesized and utilized as both a reagent and a solvent in combination with H2O2 (35%) to convert aromatic compounds into their corresponding iodo derivatives. The iodination was accomplished in the absence of organic solvents, and in most instances, water was the sole extraction solvent used. The consumed reagent N,N,N-triethyl-3-iodopropan-1-aminium iodide was comfortably recycled.
Numerical simulation of particulate matter propagation in an indoor environment with various types of heating
Authors: Issakhov Alibek , Alimbek Aidana 
Published: May 2022

Abstract
The aim of the work is to describe the air flow in an enclosed space, which is ventilated by a diffuser, to select an appropriate turbulence model, to solve the problem using the ANSYS Fluent, to study the effect of heat sources in a room on air flow under various conditions and to simulate the movement of particulate matter. As a result, the distribution of PM2.5 particles in the room was shown, which enter the room through the diffuser. According to the data obtained, the temperature value increases with an increase in the area of the heat source, that is, with an increase in the number of batteries. The maximum temperature corresponds to a room with a warm floor, the minimum temperature is observed in a room with one battery. The obtained numerical data can be used when installing ventilation or heating devices inside buildings, when simulating the movement of harmful particles in the air, when determining the optimal ways to clean the air.
Acquisition of referentiality in elicited narratives of Estonian-speaking children
Authors: Argus Reili , Kütt Andra 
Published: May 2022

Abstract
This study addresses the acquisition of referential expressions in pre-schoolers’ narratives in Estonian. A total of sixteen 6- to 7-year-old typically developing monolingual Estonian children were tested using the story “Baby Goat” from the Multilingual Assessment Instrument for Narratives (MAIN) (Gagarina, Natalia, Klop, Daleen, Kunnari, Sari, Tantele, Koula, Välimaa, Taina, Balciuniene, Ingrida, Bohnacker, Ute and Walters, Joel. 2012. “MAIN: Multilingual Assessment Instrument for Narratives.” ZAS Papers in Linguistics 56, 1–140, Gagarina, Natalia, Klop, Daleen, Kunnari, Saru, Tantele, Koula, Välimaa, Taina, Bohnacker, Ute and Walters, Joel. 2019. “MAIN: Multilingual assessment instrument for narratives – Revised.” ZAS Papers in Linguistics 63). The objective was to understand how children introduce a new referent and how they maintain referents in their storytelling, and what correlation could be observed between the length of the story and the average length of the reference chain. Qualitative analyses revealed that children generally introduced new referents using bare nouns; they also generally used bare nouns for further reference. NPs consisting of a noun and a determiner were more frequently used for main characters in the story, while bare nouns were preferred for other characters. The influence of the typological character of Estonian can be observed in the use of zero references and pragmatically driven word order in children’s utterances. In general, the length but not the complexity of the story was correlated with the average number of reference units in a chain.
Digitale Abbildung zur Prozesskoordination in der Unikatfertigung
Authors: Jericho David , Jagusch Konrad , Sender Jan , Flügge Wilko 
Published: May 2022

Abstract
Der Schiffbau ist als kundenindividuelle Unikatfertigung durch die starke Variation von zu fertigenden Baugruppen und die vornehmlich handwerkliche Fertigung und Montage geprägt. Die manuell durchgeführte Planung und Aufwandsabschätzung resultiert in hohen Aufwänden für die Produktionsplanung und -steuerung. Zur effektiveren Koordination der Prozesse bedarf es daher geeigneter Hilfsmittel. In diesem Beitrag wird ein Ansatz vorgestellt, bei dem mithilfe einer digitalen Abbildung der Produktionsprozesse die effizientere Koordination durch digitales Shopfloor Management angestrebt wird.
Produktive Machine-Learning-Systeme für die Industrie
Authors: Sara Sommer , Tapio Torikka 
Published: May 2022

Abstract
Ein Großteil der in der Industrie aktuell durchgeführten Machine-Learning-Projekte konzentriert sich auf die Pilotphase und wird nicht erfolgreich in den Produktivstatus überführt. Grund dafür ist, dass die Voraussetzungen für die Entwicklung und den Betrieb einer produktiven Lösung in Industrieunternehmen häufig nicht bekannt und daher nicht gegeben sind. Daher wurde in diesem Beitrag auf die Unterschiede zwischen Machine-Learning-Pilotprojekten und -Produktivsystemen eingegangen. Zudem wird beleuchtet, wie durch die Nutzung von MLOps und einem geeigneten Kompetenz-Setup die Wahrscheinlichkeit, dass ein Pilotprojekt erfolgreich in den Produktivbetrieb überführt wird, erhöht werden kann.
Slow Inactivation of Sodium Channels Contributes to Short-Term Adaptation in Vomeronasal Sensory Neurons
Authors: Sarno Nicole , Hernandez-Clavijo Andres , Boccaccio Anna , Menini Anna , Pifferi Simone 
Published: May 2022

AbstractAdaptation plays an important role in sensory systems as it dynamically modifies sensitivity to allow the detection of stimulus changes. The vomeronasal system controls many social behaviors in most mammals by detecting pheromones released by conspecifics. Stimuli activate a transduction cascade in vomeronasal neurons that leads to spiking activity. Whether and how these neurons adapt to stimuli is still debated and largely unknown. Here, we measured short-term adaptation performing current-clamp whole-cell recordings by using diluted urine as a stimulus, as it contains many pheromones. We measured spike frequency adaptation in response to repeated identical stimuli of 2–10 s duration that was dependent on the time interval between stimuli. Responses to paired current steps, bypassing the signal transduction cascade, also showed spike frequency adaptation. We found that voltage-gated Na+channels in VSNs undergo slow inactivation processes. Furthermore, recovery from slow inactivation of voltage-gated Na+channels occurs in several seconds, a time scale similar to that measured during paired-pulse adaptation protocols, suggesting that it partially contributes to short-term spike frequency adaptation. We conclude that vomeronasal neurons do exhibit a time-dependent short-term spike frequency adaptation to repeated natural stimuli and that slow inactivation of Na+channels contributes to this form of adaptation. These findings not only increase our knowledge about adaptation in the vomeronasal system, but also raise the question of whether slow inactivation of Na+channels may play a role in other sensory systems.
The Realization of Communication Tasks in Negotiating Meaning among EFL learners
Authors: Rachma Nita Sitta , Faridi Abdurrachman , Rukmini Dwi 
Published: May 2022

People currently live at a time where the ability to speak English fluently has become a must for those who attempt to advance in certain fields. In classroom context however communication task is considered as a crucial element of English language teaching. As a strategy of communication, negotiation of meaning plays as a process through which the speakers go to clearly comprehend one another. The aims of this study are to analyze the realization of different communication tasks in negotiating meaning and to dig up those tasks in order to explain its impact on negotiation of meaning. A qualitative method is applied in this study where twenty undergraduate students majoring in English Language Education took part in it. The students were paired and assigned to perform five different communication tasks. The result showed that communication tasks had been effectively used as an opportunity for students to elicit the occurrences of negotiation of meaning in interactions. Moreover, it was discovered that each task type yielded different amount of negotiation. Information gap task came out as the most productive task in promoting negotiation of meaning among the other four with some negotiation of meaning strategies employed by students during negotiation; clarification request, confirmation checks, and comprehension checks. In conclusion, engaging students in such communication tasks leading to negotiating meaning helps them in developing their linguistic acknowledgement. It is due to the frequent use of negotiation of meaning strategies can contribute to language development of EFL learners in all level of proficiency.