bluuebunny/crossref_metadata_2025_split huggingface dataset:
A comparative study for the assessment of Ikonos satellite image-fusion techniques
Authors: Medina Javier , Vera Nelson , Upegui Erika 
Published: January 2022

I<span>Image-fusion provide users with detailed information about the urban and rural environment, which is useful for applications such as urban planning and management when higher spatial resolution images are not available. There are different image fusion methods. This paper implements, evaluates, and compares six satellite image-fusion methods, namely wavelet 2D-M transform, gram schmidt, high-frequency modulation, high pass filter (HPF) transform, simple mean value, and PCA. An Ikonos image (Panchromatic-PAN and multispectral-MULTI) showing the northwest of Bogotá (Colombia) is used to generate six fused images</span>: MULTI<sub>Wavelet 2D-M</sub>, MULTI<sub>G-S</sub>, MULTI<sub>MHF</sub>, MULTI<sub>HPF</sub>, MULTI<sub>SMV</sub>, and MULTI<sub>PCA</sub>. <span>In order to assess the efficiency of the six image-fusion methods, the resulting images were evaluated in terms of both spatial quality and spectral quality. To this end, four metrics were applied, namely the correlation index, erreur relative globale adimensionnelle de synthese (ERGAS), relative average spectral error (RASE) and the Q index. The best results were obtained for the </span> MULTI<sub>SMV</sub> image, which exhibited spectral correlation higher than 0.85, a Q index of 0.84, and the highest scores in spectral assessment according to ERGAS and RASE, 4.36% and 17.39% respectively.
Reference-free differential histogram-correlative detection of steganography: performance analysis
Authors: Abdali Natiq M. , Hussain Zahir M. 
Published: January 2022

<span lang="EN-US">Recent <span>research has demonstrated the effectiveness of utilizing neural networks for detect tampering in images. However, because accessing a database is complex, which is needed in the classification process to detect tampering, reference-free steganalysis attracted attention. In recent work, an approach for least significant bit (LSB) steganalysis has been presented based on analyzing the derivatives of the histogram correlation. In this paper, we further examine this strategy for other steganographic methods. Detecting image tampering in the spatial domain, such as image steganography. It is found that the above approach could be applied successfully to other kinds of steganography with different orders of histogram-correlation derivatives. Also, the limits of the ratio stego-image to cover are considered, where very small ratios can escape this detection method unless </span> modified.</span>
Sliding mode control with observer for permanent magnet synchronous machine drives
Authors: Razali Muhammad Haziq Nashren , Lazi Jurifa Mat , Ibrahim Zulkifilie , Talib Md Hairul Nizam , Patakor Fizatul Aini 
Published: January 2022

<span lang="EN-US">This <span>paper aims to develop the sliding mode control (SMC) scheme in sensorless permanent magnet synchronous machine (PMSM) drives to replace conventional proportional integral (PI) speed control. The SMC is formulated based on the integral sliding surface of the speed error. And the error is corrected based on the concept of Lyapunov stability. The SMC is designed with the load torque observer so that the disturbance can be estimated as feedback to the controller. The vector control technique which is also known as field-oriented control (FOC) is also used to split the stator current into the magnetic field generating part which is the direct axis and the torque generating part which is the quadrature axis. This can be done by using Park and Clarke transformations. The performance of the proposed SMC is tested under changes in load-torque and without load for different speed commands. The results prove that the SMC produces robust performances under variations of speeds and load disturbances. The effectiveness of the proposed method is verified and simulated by using MATLAB/SIMULINK </span>software.</span>
DIVERSITY OF ENDOPHYTIC FUNGI ASSOCIATED WITH FRUITS AND LEAVES OF TAMARIND (Tamarindusindica L.) BASED O N ITS RIBOSOMAL DNA SEQUENCES
Authors: Mohd Zainudin Nur Ain Izzati , Mohd Zaini Nurul Asyiqin , Md Nizam Nurul Huwaidah , Awg Zainal Abidin Dayang Fatin Zafira , Mohd Nazri Nor Izanis Azni 
Published: January 2022

Plant-associated microbes are among the important natural resources that abundantly exist in natural environment such as endophytic fungi. The studies on endophytic fungi in medicinal plants have allowed the discovery of numerous fungi species and their hidden potentials. Therefore, this study focused on the isolation and identification of endophytic fungi from several plant parts of tamarind such as leaves and fruits. A total of 69 fungal cultures were successfully isolated and identified into 33 distinct species from 14 genera based on morphological characteristics and internal transcribed spacer (ITS) sequence analysis using a Maximum Likelihood method. There were six different species obtained from the genus Colletotrichum (C. aenigma, C. brevisporum, C. cobbittiense, C. fructicola, C. gloeosporioides and C. siamense), and Diaporthe (D. arecae, D. ceratozamiae, D. phaseolorum, D. pseudomangiferae, D. pseudooculiÂ and D. pseudophoenicicola), four species of Aspergillus (A. aculeatus, A. carbonarius, A. flavus and A. tubingensis), three species of Curvularia (C. aeria , C. geniculata and C. lunata) and Nigrospora (N. lacticolonia, N. oryzae and N. sphaerica), two species of Lasiodiplodia (L. pseudotheobromae and L. theobromae) and Penicillium (P. rolfsii and P. verruculosum). Other fungal species that were also identified are Botryosphaeria mamane, Fusarium solani, Perenniporia tephropora, Phyllosticta fallopiae, Sarcostroma bisetulatum, Trichoderma asperellum and Xylaria feejeensis. The isolates were grouped into different clades according to their class. In conclusion, endophytic fungi isolated from tamarind plant are diverse and provides an insight into species diversity of endophytic fungi in tamarind.
Moyamoya Disease Susceptibility Gene
RNF213
Regulates Endothelial Barrier Function
Authors: Roy Vincent , Ross Jay P. , Pépin Rémy , Cortez Ghio Sergio , Brodeur Alyssa , Touzel Deschênes Lydia , Le-Bel Gaëtan , Phillips Daniel E. , Milot Geneviève , Dion Patrick A. , Guérin Sylvain , Germain Lucie , Berthod François , Auger François A. , Rouleau Guy A. , Dupré Nicolas , Gros-Louis François 
Published: January 2022

Background:

Variants in the ring finger protein 213 (
RNF213
) gene are known to be associated with increased predisposition to cerebrovascular diseases development. Genomic studies have identified
RNF213
as a major risk factor of Moyamoya disease in East Asian descendants. However, little is known about the RNF213 (ring finger protein 213) biological functions or its associated pathogenic mechanisms underlying Moyamoya disease.

Methods:
To investigate RNF213 loss-of-function effect in endothelial cell, stable RNF213-deficient human cerebral endothelial cells were generated using the CRISPR-Cas9 genome editing technology.

Results:
In vitro assays, using RNF213 knockout brain endothelial cells, showed clear morphological changes and increased blood-brain barrier permeability. Downregulation and delocalization of essential interendothelial junction proteins involved in the blood-brain barrier maintenance, such as PECAM-1 (platelet endothelial cell adhesion molecule-1), was also observed. Brain endothelial RNF213-deficient cells also showed an abnormal potential to transmigration of leukocytes and secreted high amounts of proinflammatory cytokines.

Conclusions:
Taken together, these results indicate that RNF213 could be a key regulator of cerebral endothelium integrity, whose disruption could be an early pathological mechanism leading to Moyamoya disease. This study also further reinforces the importance of blood-brain barrier integrity in the development of Moyamoya disease and other RNF213-associated diseases.
Endogenous Deoxyribonuclease Activity and Cell-Free Deoxyribonucleic Acid in Acute Ischemic Stroke: A Cohort Study
Authors: Grosse Gerrit M. , Blume Nicole , Abu-Fares Omar , Götz Friedrich , Ernst Johanna , Leotescu Andrei , Gabriel Maria M. , van Gemmeren Till , Worthmann Hans , Lichtinghagen Ralf , Imker Rabea , Falk Christine S. , Weissenborn Karin , Schuppner Ramona , de Buhr Nicole 
Published: January 2022

Background:
Cell-free DNA (cfDNA) and endogenous deoxyribonuclease activity are opposing mediators and might influence the inflammatory response following acute ischemic stroke. In this cohort study, we investigated the relation between these markers, circulating inflammatory mediators and clinical course including occurrence of stroke-associated infections (SAI) in patients with acute stroke.

Methods:
Ninety-two patients with stroke due to large vessel occlusion undergoing mechanical thrombectomy were prospectively recruited at Hannover Medical School from March 2018 to August 2019. Deoxyribonuclease activity, cfDNA, damage-associated molecular patterns, and circulating cytokines were measured in venous blood collected immediately before mechanical thrombectomy and 7 days later. Reperfusion status was categorized (sufficient/insufficient). Clinical outcome was evaluated using the modified Rankin Scale after 90 days, where a score of 3 to 6 was considered unfavorable. To validate findings regarding SAI, another stroke cohort (n=92) was considered with blood taken within 24 hours after stroke onset.

Results:
Patients with unfavorable clinical outcome had higher cfDNA concentrations. After adjustment for confounders (Essen Stroke Risk Score, National Institutes of Health Stroke Scale, and sex), 7-day cfDNA was independently associated with clinical outcome and especially mortality (adjusted odds ratio: 3.485 [95% CI, 1.001–12.134] and adjusted odds ratio: 9.585 [95% CI, 2.006–45.790]). No association was found between reperfusion status and cfDNA or deoxyribonuclease activity. While cfDNA concentrations correlated positively, deoxyribonuclease activity inversely correlated with distinct biomarkers. Baseline deoxyribonuclease activity was lower in patients who developed SAI compared with patients without SAI. This association was confirmed after adjustment for confounding factors (adjusted odds ratio: 0.447 [95% CI, 0.237–0.844]). In cohort 2, differences of deoxyribonuclease activity between patients with and without SAI tended to be higher with higher stroke severity.

Conclusions:
The interplay of endogenous deoxyribonuclease activity and cfDNA in acute stroke entails interesting novel diagnostic and potential therapeutic approaches. We confirm an independent association of cfDNA with a detrimental clinical course after stroke due to large vessel occlusion. This study provides first evidence for lower endogenous deoxyribonuclease activity as risk factor for SAI after severe stroke.
Xenophon and the Orators on the Topography of Arginousae and Aegospotami
Authors: Kapellos Aggelos 
Published: January 2022

Abstract
In his description of the naval battles of Arginousae and Aegospotami Xenophon integrated detailed topographical data into the historical description of war operations because he regarded them as absolutely necessary elements of his text, which was intended as a tool of understanding and interpretation. On the other hand, the orators tend not to use the names of Arginousae and Aegospotami when referring to the episodes which occurred there, and they write in a way that shows that their fellow citizens did not want to know or remember the topography of these naval battles, since this would have evoked painful memories to them.
Acute Herpetic Nasopharyngitis in an Adult Patient: A Case Report and Literature Review
Authors: Kuo Cathleen C. , Piccillo Ellen M. , DeGiovanni Jason C. , Kabalan Matt , Zimmer Gregg , Carr Michele M. 
Published: January 2022

Objective: To report a case of herpes virus-associated nasopharyngitis in an adult patient. Methods: The patient’s medical record was reviewed for demographic and clinical data. For literature review, all case reports or other publications published in English literature were identified using Pubmed with the MeSH terms “herpes,” “nasopharyngitis,” and “upper respiratory infection.” Results: A 40-year-old male presented for nasal congestion and a suspected nasal mass. Computed tomography of the sinuses revealed edematous changes in the nasopharynx which exerted a downward mass effect at the right aspect of the soft palate. Flexible fiberoptic laryngoscopy (FFL) revealed a lesion arising from the posterior aspect of the soft palate with extension into the posterior nasal cavity as well as copious mucopurulent secretions consistent with a superimposed acute sinusitis. Rigid nasal endoscopy demonstrated a friable and ulcerated lesion arising from the aforementioned anatomical location. Biopsy of this lesion and subsequent immunohistochemical analysis revealed a diagnosis of herpetic nasopharyngitis. Conclusions: Herpetic infection should be in the differential diagnosis of patients presenting with atypical symptoms of nasopharyngitis. Early accurate diagnosis and appropriate specific management can limit the duration of disease course and prevent further complications.
Evaluation of the effects of Covid-19 on cochleovestibular system with audiovestibular tests
Authors: Bozdemir Kazım , Çallıoğlu Elif Ersoy , İslamoğlu Yüce , Ercan Mehmet Kadir , Eser Fatma , Özdem Birsen , Kıraç Arda , Bayazıt Dilara , Güner Rahmet , Babademez Mehmet ali 
Published: January 2022

Purpose The purpose of the present study was to investigate the effects of COVID-19 on audiovestibular system with Transiently Evoked Distortion Otoacoustic Emissions (TOAE), Distortion Product Otoacoustic Emissions (DPOAE), video head impulse test (vHIT) and caloric test. Methods Audiovestibular findings of 24 patients with moderate/severe COVID-19 and 24 healthy controls were compared using pure tone audiometry, tympanometry, TOAE, DPOAE, caloric test, and vHIT. Results On audiometry, the pure tone averages of the COVID-19 patients were higher than the controls ( P = .038). The TEOAE amplitudes at 4000 and 5000 Hz ( P = .006 and P < .01), and DPOAE amplitudes at 3000, 6000, and 8000 Hz ( P < .001, P = .003 and P < .001) were significantly lower in COVID-19 patients compared to the controls. On vestibular tests, there was no significant difference between the caloric test results of the patients and the controls ( P > .05). On vHIT testing, amplitudes of right semicircular canal was found to be significantly lower in COVID-19 group compared to the control group ( P = .008). Conclusion COVID-19 may affect inner ear functions causing a subtle damage in the outer hair cells and lateral semicircular canals. It must be kept in mind that COVID-19 may cause cochleovestibular problems.
Correlation between vitamin D levels and bone metabolism in children with cow’s milk allergy
Authors: Che Di , Yu Li , Guo Yong , Ke Hai-jin , Liu Cui , Wu Jie-Ling 
Published: January 2022

Objective Research is limited regarding biochemical markers of bone metabolism among children with cow’s milk protein allergy (CMPA). We aimed to determine differences in vitamin D and bone metabolism markers between infants with CMPA and healthy infants and explore relationships between these in a cross-sectional study. Methods In total, we included 41 children diagnosed with CMPA and under systematic medical and nutritional care at our center, and 50 healthy children as a control group. We reviewed demographic and clinical characteristics and measured serum biomarkers. Results We found that serum 25-hydroxyvitamin D (25(OH)D) levels among infants in the CMPA group were significantly lower than those in the control group, and levels of bone-specific alkaline phosphatase (BALP), serum phosphorus, and serum calcitonin were reduced. Pearson correlation analysis showed that serum 25(OH)D concentrations in the CMPA group were negatively correlated with parathyroid hormone but not significantly correlated with calcitonin and BALP. Logistic regression showed that CMPA was a risk factor for vitamin D deficiency. Conclusions Our study indicated that CMPA was associated with disturbances in bone metabolism. Levels of vitamin D in children with CMPA were lower than those in healthy children. CMPA was a risk factor for vitamin D deficiency.
Comprehensive meta-analysis of associations between temperament and character traits in Cloninger’s psychobiological theory and mental disorders
Authors: Komasi Saeid , Rezaei Farzin , Hemmati Azad , Rahmani Khaled , Amianto Federico , Miettunen Jouko 
Published: January 2022

Objective To explore the relationship between temperament and character traits in Cloninger’s psychobiological theory and mental disorders. Methods: A systematic literature search was conducted of five international databases for all articles published in English between January 1990 and April 2019 (PROSPERO-CRD42019133214). Owing to heterogeneity, pooled estimates of correlations for personality disorders and standardized mean differences for case–control studies related to other mental disorders were calculated using the random-effects method. Results The pooled effect sizes obtained from 149 studies showed that high harm avoidance (related to 22/24 diagnostic categories), low self-directedness (21/23), low cooperativeness (17/23), high self-transcendence (14/23), low reward dependence (11/24), high novelty-seeking (10/24), low novelty-seeking (7/24), high persistence (2/23), low persistence (2/23) and high reward dependence (2/24) were related to psychopathology. Conclusions All traits provided unique psychobiological tools for differential diagnosis of mental disorders. However, high harm avoidance and low self-directedness played a canonical role in psychopathology. Despite the study limitations, additional studies are warranted to evaluate the differential diagnoses suggested by the present model.
Vegetables for Healthy Diets in Low- and Middle-Income Countries: A Scoping Review of the Food Systems Literature
Authors: Harris Jody , Tan Winson , Raneri Jessica E. , Schreinemachers Pepijn , Herforth Anna 
Published: January 2022

Background: Vegetables are an essential element in healthy diets, but intakes are low around the world and there is a lack of systematic knowledge on how to improve diets through food system approaches. Methods: This scoping review assessed how studies of food systems for healthy diets have addressed the role of vegetables in low- and middle-income countries. We apply the PRISMA guidelines for scoping reviews to narratively map the literature to an accepted food systems framework and identify research gaps. Results: We found 1383 relevant articles, with increasing numbers over 20 years. Only 6% of articles looked at low-income countries, and 93% looked at single-country contexts. Over half of articles assessed vegetables as a food group, without looking at diversity within the food group. 15% looked at traditional vegetables. Issues of physical access to food were among the least studied food system topics in our review (7% of articles). Only 15% of articles used a comprehensive food system lens across multiple dimensions. There is also a research gap on the impacts of different policy and practice interventions (13% of articles) to enable greater vegetable consumption. Conclusions: Food system studies necessarily drew on multiple disciplines, methods and metrics to describe, analyze, and diagnose parts of the system. More work is needed across disciplines, across contexts, and across the food system, including understanding interventions and trade-offs, and impacts and change for diets particularly of marginalized population groups. Filling these gaps in knowledge is necessary in order to work toward healthy vegetable-rich diets for everyone everywhere.
Gender Related Differences in Gastrointestinal Bleeding With Oral Anticoagulation in Atrial Fibrillation
Authors: Ferroni Eliana , Denas Gentian , Gennaro Nicola , Fedeli Ugo , Pengo Vittorio 
Published: January 2022

Background: DOACs are characterized by a higher incidence of gastrointestinal bleeding and this may be different among males and females. Female patients were underrepresented in the DOAC pivotal trials. We aimed to assess real-world differences in gastrointestinal bleeding with oral anticoagulants (DOACs and VKAs) among males and females with atrial fibrillation. Methods: We performed a population-based retrospective analysis on linked administrative claims. Atrial fibrillation patients of 65 years and above were considered. Bleeding risk factors were assessed through HASBED and previous history of gastrointestinal disease. A time-to-event analysis compared gastrointestinal bleeding between males and females. Results: The overall cohort consisted of 15338 (55% female) DOAC and 44542 (50% female) VKA users. Most of the patients showed HASBED ≥2. Incidence rate of GI bleeding was higher in females as compared to males among DOAC users (0.90% vs 0.59%), and significant gender difference in GI bleeding was found, after adjustment, in the Cox regression analysis (HR 1.48, 95%CI 1.02-2.16). In the VKA group, no significant difference among genders was found in the time-to-event analysis. Conclusions: Our data suggest that female patients treated with DOACs have a higher risk of GI bleeding versus male patients; this difference is not observed in VKA patients.
IV Sodium Ferric Gluconate Complex in Patients Hospitalized Due to Acute Decompensated Heart Failure and Iron Deficiency
Authors: Borreda Itay , Zukermann Robert , Epstein Danny , Marcusohn Erez 
Published: January 2022

Background: Patients suffering from heart failure (HF) and iron deficiency (ID) have worse outcomes. Treatment with intra-venous (IV) ferric carboxymaltose has been shown to reduce HF rehospitalizations and to improve functional capacity and symptoms in patients with HF and reduced ejection fraction (HFrEF). However, IV ferric carboxymaltose is significantly more expensive than IV sodium ferric gluconate complex (SFGC) limiting its availability to most HF patients around the globe. Methods: A retrospective analysis comparing patients admitted to internal medicine or cardiology departments between January 2013 to December 2018 due to acute decompensated HF (ADHF) and treated with or without IV SFGC on top of standard medical therapy. Results: During the study period, a total of 1863 patients were hospitalized due to ADHF with either HFrEF or HF with preserved ejection fraction (HFpEF). Among them, 840 patients had laboratory evidence of iron deficiency (absolute or functional) and met the inclusion criteria. One hundred twenty-two of them (14.5%) were treated with IV SFGC during the index hospitalization. Patients treated with IV iron were more likely to have history of ischemic heart disease, atrial fibrillation, and chronic kidney disease. The rate of readmissions due to ADHF was similar between the groups at 30 days, 3 months, and 1 year. Conclusion: High risk patient hospitalized to ADHF and treated with IV SFGC showed comparable ADHF readmission rates, compared to those who did not receive iron supplementation.