bluuebunny/crossref_metadata_2025_split huggingface dataset:
Breastfeeding outcomes in late preterm infants: A multi-centre prospective cohort study
Authors: Keir Amy , Rumbold Alice , Collins Carmel T. , McPhee Andrew J. , Varghese Jojy , Morris Scott , Sullivan Thomas R. , Leemaqz Shalem , Middleton Philippa , Makrides Maria , Best Karen P. 
Published: August 2022

Objectives
To describe (1) infant feeding practices during initial hospitalisation and up to 6 months corrected age (CA) in infants born late preterm with mothers intending to breastfeed, (2) the impact of early feeding practices on hospital length of stay and (3) maternal and infant factors associated with duration of breastfeeding.

Methods
We conducted a prospective cohort study of infants born at 34+0 to 36+6 weeks gestational age during 2018–2020. Families were followed up until the infant reached 6 months of age (corrected for prematurity). Feeding practices during the birth hospitalisation, length of initial hospital stay, and the prevalence of exclusive or any breastfeeding at 6 weeks, 3 months, and 6 months CA were examined. Associations between maternal and infant characteristics and breastfeeding at 6 weeks, 3 months and 6 months CA were assessed using multivariable logistic regression models.

Results
270 infants were enrolled, of these, 30% were multiple births. Overall, 78% of infants received only breastmilk as their first feed, and 83% received formula during the hospitalisation. Seventy-four per cent of infants were exclusively breastfed at discharge, 41% at 6 weeks CA, 35% at 3 months CA, and 29% at 6 months CA. The corresponding combined exclusive and partial breastfeeding rates (any breastfeeding) were 72%, 64%, and 53% of babies at 6 weeks CA, 3 months CA, and 6 months CA, respectively. The mean duration of hospitalisation was 2.9 days longer (95% confidence interval (CI) 0.31, 5.43 days) in infants who received any formula compared with those receiving only breastmilk (adjusted for GA, maternal age, multiple birth, site, and neonatal intensive care unit admission). In multivariable models, receipt of formula as the first milk feed was associated with a reduction in exclusive breastfeeding at 6 weeks CA (odds ratio = 0.22; 95% CI 0.09 to 0.53) and intention to breastfeed >6 months with an increase (odds ratio = 4.98; 95% CI 2.39 to 10.40). Intention to breastfeed >6 months remained an important predictor of exclusive breastfeeding at 3 and 6 months CA.

Conclusions
Our study demonstrates that long-term exclusive breastfeeding rates were low in a cohort of women intending to provide breastmilk to their late preterm infants, with approximately half providing any breastmilk at 6 months CA. Formula as the first milk feed and intention to breastfeed >6 months were significant predictors of breastfeeding duration. Improving breastfeeding outcomes may require strategies to support early lactation and a better understanding of the ongoing support needs of this population.
Response inhibition in the Negative Compatibility Effect in the absence of inhibitory stimulus features
Authors: Schmidt Thomas , Panis Sven , Wolkersdorfer Maximilian P. , Vorberg Dirk 
Published: August 2022

AbstractThe Negative Compatibility Effect (NCE) is a reversal in priming effects that can occur when a masked arrow prime is followed by an arrow target at a long stimulus-onset asynchrony (SOA). To test the explanation that the NCE is actually a positive priming effect elicited by mask features associated with the prime-opposed response, we devise masks that always point in the same direction as the prime, eliminating all antiprime features. We find large positive priming effects for arrow primes without masks and for arrow masks without primes. When a neutral mask is introduced, priming effects turn negative at long SOAs. In the critical case where the mask is an arrow in the same direction as the prime, the prime does not add to the positive priming effect from the mask shape, but instead strongly diminishes it and induces response errors even though all stimuli point in the same direction. No such feature-free inhibition is seen when arrows are replaced by color stimuli. We conclude that even though response activation by stimulus features plays a role in the NCE, there is a strong inhibitory component (though perhaps not in all feature domains) that is not based on visual features.
Bipolar‐associated miR‐499‐5p controls neuroplasticity by downregulating the Cav1.2 subunit CACNB2
Authors: Martins Helena C , Gilardi Carlotta , Sungur A Özge , Winterer Jochen , Pelzl Michael A , Bicker Silvia , Gross Fridolin , Kisko Theresa M , Malikowska‐Racia Natalia , Braun Moria D , Brosch Katharina , Nenadic Igor , Stein Frederike , Meinert Susanne , Schwarting Rainer K W , Dannlowski Udo , Kircher Tilo , Wöhr Markus , Schratt Gerhard 
Published: August 2022

AbstractBipolar disorder (BD) is a chronic mood disorder characterized by manic and depressive episodes. Dysregulation of neuroplasticity and calcium homeostasis are frequently observed in BD patients, but the underlying molecular mechanisms are largely unknown. Here, we show that miR‐499‐5p regulates dendritogenesis and cognitive function by downregulating the BD risk gene CACNB2. miR‐499‐5p expression is increased in peripheral blood of BD patients, as well as in the hippocampus of rats which underwent juvenile social isolation. In rat hippocampal neurons, miR‐499‐5p impairs dendritogenesis and reduces surface expression and activity of the L‐type calcium channel Cav1.2. We further identified CACNB2, which encodes a regulatory β‐subunit of Cav1.2, as a direct functional target of miR‐499‐5p in neurons. miR‐499‐5p overexpression in the hippocampus in vivo induces short‐term memory impairments selectively in rats haploinsufficient for the Cav1.2 pore forming subunit Cacna1c. In humans, miR‐499‐5p expression is negatively associated with gray matter volumes of the left superior temporal gyrus, a region implicated in auditory and emotional processing. We propose that stress‐induced miR‐499‐5p overexpression contributes to dendritic impairments, deregulated calcium homeostasis, and neurocognitive dysfunction in BD.
Actitudes docentes hacia la investigación científica y autoevaluación de su enseñanza
Authors: Vargas-Delgado Leonardo José , Avila-Toscano Jose , De-la-Rosa-Ibáñez Hermes David , Jiménez-Zúñiga Juan José , Hernández-Chang Emilio Ariel 
Published: August 2022

Introducción: Las actitudes docentes hacia la investigación influyen en la percepción e interés del estudiante afectando su enseñanza en el aula. Objetivo: Evaluar actitudes hacia la investigación en docentes, desde la relación con su enseñanza, e identificando si las actitudes y la autoevaluación muestran diferencias en función del nivel educativo donde se desempeña el profesor y su formación de pregrado en investigación. Metodología: Estudio correlacional simple con 214 docentes, evaluados con la Escala de Actitudes hacia la Investigación Revisada (EACIN-R) para identificar las actitudes desinterés, vocación y valoración, y un cuestionario ad hoc de autoevaluación del interés, uso y seguridad al enseñar investigación. Resultados: Las actitudes vocación (rho = 0.55, p < 0.001) y valoración investigativa (rho=.33, p < 0.001) correlacionan positivamente con la autoevaluación docente, mientras que el desinterés se relaciona de forma inversa (rho = –0.35, p < 0.001). La autoevaluación de la enseñanza en investigación es mayor en docentes de preescolar (U = 4071.5, p < 0.01) y en quienes tienen antecedentes investigativos en el pregrado (U = 4459.5, p < 0.01). Conclusiones: Son notorias las relaciones entre actitudes y autoevaluación de la enseñanza de investigación, siendo particularmente valiosa la experiencia investigativa (participar en semilleros, realizar tesis de grado) durante la formación inicial.
Interculturalidad en los procesos de enseñanza y aprendizaje del inglés como lengua extranjera
Authors: Florez-Montaño Sebastian , Zapata-Garcia Jefferson Asdrubal , Peláez-Henao Oscar Alberto 
Published: August 2022

Introducción: Las instituciones educativas son espacios complejos en los cuales confluyen subjetividades propias de cada individuo y donde el lenguaje tiene un papel fundamental. En este sentido, los profesores de inglés deben ser mediadores entre las múltiples culturas en un aula de clases. La capacidad de utilizar el idioma de manera social y culturalmente apropiada, más la conciencia que deben tener los docentes y los estudiantes en el aula con respecto a la diversidad y complejidad es la base para la construcción de una sociedad democrática. Objetivo: Este artículo de revisión de la literatura pretende establecer la relación entre las percepciones de los docentes sobre la interculturalidad y los procesos de enseñanza y aprendizaje del inglés a través la concientización y contrastación que hace el estudiante de su propia cultura con respecto a otras, y mediante el análisis crítico de las relaciones entre las personas a través de las diferencias culturales. Metodología: Se utilizan técnicas cualitativas para la selección y recopilación de información por medio de la lectura y crítica de documentos y materiales bibliográficos. Usando diversas bases de datos y después de aplicar técnicas de selección en las fuentes primarias identificadas se conforma una muestra de cincuenta artículos científicos. Resultados y discusión: Luego del análisis temático, los resultados se presentan en tres categorías: estrategias utilizadas por los docentes en el aula para potenciar la competencia intercultural, desafíos que enfrentan y el papel que juegan los docentes como agentes culturales. Conclusiones: El estudio concluye que existen desafíos y limitaciones cuando se promueve la competencia intercultural en el aula. Los profesores son percibidos como modelos para los estudiantes, lo que se convierte en un esfuerzo primordial para ellos; pero al mismo tiempo, una labor digna considerando que las escuelas son laboratorios para iniciar la construcción de una sociedad más democrática y diversa.
This literature review article is an examination between of teachers’ perceptions about interculturality and English teaching and learning. The ability to use the language in socially and culturally appropriate ways plus the awareness teachers and learners should have in the classroom in regards to the diversity and complexity is the basis for the construction of a democratic society. Using a variety of data bases and after dismissing many primary sources, 50 were selected. After the thematic analysis, the results are presented in three categories: strategies used by teachers in the classroom to enhance intercultural competence, challenges they face, and the role teachers play as cultural agents. The study concludes that there are challenges and constraints when intercultural competence is promoted in the classroom. However, this a paramount endeavour to build a more democratic and diverse society.
Febuxostat as an effective drug of choice for urate-lowering therapy for gout (case report)
Authors: Bashkova A. B. , Madyanov I. V. 
Published: August 2022

The prognosis for gout is largely determined by its timely diagnosis and the choice of drugs for effective urate-lowering therapy which considers the peculiarity of a particular patient’s disease course: the signs of complications, comorbid pathology, and drug tolerability. The report presents a clinical case of gout, which a 30-year-old man with acute arthritis of the right big toe experienced for the first time. The diagnosis of gout was verified by a rheumatologist only 6 years after the first attack. In addition to gout, the patient was also diagnosed with urolithiasis, obesity, hypertension, prediabetes and dyslipoproteinemia. Initially, allopurinol was prescribed, which at a dose of 300 mg/day ensured the achievement of the target level of uric acid. However, the patient stopped taking the drug and eased the frequent gouty attacks by taking nonsteroidal anti-inflammatory drugs. He turned to the rheumatologist again 2 years later. The level of uric acid in the blood was 744 umol/l, the glomerular filtration rate (GFR) was 55 ml/min. The resumption of allopurinol intake was accompanied by the development of dermatitis. Therefore, instead of allopurinol, febuxostat was prescribed, which at a dose of 120 mg/day ensured the achievement of a normal level of uric acid. At this dose, the patient has been taking the drug for the last 2.5 years. The drug tolerability is good. An improvement in kidney function (GFR – 89 ml/min) and normalization of carbohydrate metabolism were recorded associated with medication intake. Thus, febuxostat for gout is an effective drug for urate-lowering therapy. prescription is especially recommended in case of intolerance to allopurinol and kidney damage.
Structure of reproductive losses of adolescent girls and women of reproductive age in the Tyumen
Authors: Mateykovich E. A. , Novikova V. A. , Radzinsky V. E. , Mateykovich M. S. 
Published: August 2022

Introduction. The reproductive experience of women 18–44 years of age is quantitatively superior to adolescent girls. The structure of reproductive losses of adolescents, its identity or difference in comparison with women of reproductive age is extremely unexplored.Aim. To compare the structure of reproductive losses of adolescents and women of reproductive age on the example of the Tyumen region.Materials and methods.A retro-prospective analytical study carried out. Study period – 2016–2021. Adolescent girls and women of reproductive age with completed pregnancies included.Results and discussion. In the Tyumen region, the frequency of reproductive losses approaches childbirth (42.83% and 57.17%), mainly represented by medical abortion (59.98%). The proportion of completed pregnancies among adolescent girls (1.14%) is inferior to women of reproductive age (98.86%). Adolescent girls are characterized by the completion of pregnancy by childbirth (OR = 1.68), a high frequency of medical abortion (OR = 1.71). Reproductive losses up to 12 weeks distinguish completed pregnancies in women of reproductive age (OR = 1.68); unsuccessful abortion attempt, criminal and unspecified types of abortion before 12 weeks and other abnormal products of conception after 12 weeks are their exclusive markers. The pregnancy outcome is associated with age: with adolescents – medical abortion before (OR = 1.71) and after 12 weeks (OR = 2.01); with reproductive age – other abnormal products of conception (OR = 1.64) and ectopic pregnancy (OR = 6.15). Reproductive losses are associated with gestational age before/after 12 weeks: with adolescents – spontaneous abortion after 12 weeks (OR = 2.55); with reproductive age – other types of abortion (OR = 20.37), medical abortion (OR = 1.93), other abnormal products of conception (OR = 1.89) before 12 weeks and spontaneous abortion (OR = 5.42) after 12 weeks.Conclusion.In the Tyumen region, reproductive losses in frequency compete with childbirth. Augmented the concept of the abortion-contraceptive behavior of modern society based on the association of medical abortion with adolescent girls that we have identified. The structure of reproductive losses is associated with a woman’s age period and gestational age.
Coronary heart disease and depressive disorders, pathogenesis and actual features of the relationship
Authors: Gilyarov M. Yu. , Konstantinova E. V. , Koroleva E. A. , Popova A. G. , Popov E. E. , Anichkov D. A. , Raschetnova N. I. , Svet A. V. 
Published: August 2022

In the conditions of the existing pandemic, that affects both the physical and psychological health of people, it can be predicted with a high degree of probability an outbreak in mental disorders and stress-associated mental illnesses, including depression. The problem of the relationship between depression and cardiac diseases, in particular coronary heart disease (CHD), has been studied by native and foreign scientists for several decades. Various mechanisms have been found and continue to be studied, indicating that the presence of depression can affect more or less on the course of coronary heart disease and even become a predictor of new cardiac events. Dysfunction of the autonomic nervous system with changes in heart rate variability, hyperactivity of the hypothalamic-pituitary-adrenal axis and associated hypercortisolemia, disorders of serotonergic signal transmission pathways, high aggregation response and increased platelet activity, continuous increase of proinflammatory cytokines ((IL17A, IL6, TNFa and IL12p70) in patients’ plasma – such mechanisms probably underlie the correlation between depression and an increased risk of cardiovascular complications and cardiac death. The review includes some features of depression and its influence on various forms of coronary heart disease, particularly in different age and gender groups. In view of the ongoing COVID-19 pandemic, this theme seems to be relevant and requires targeted study. Probably it is necessary to conduct clinical researches, to create registers for a detailed assessment of the mutual influence of depression and coronary heart disease in existing conditions. Perhaps, the results of such work will contribute not only to the early detection and treatment of depression, but also to the development of new ways in primary and secondary prevention of coronary heart disease and its acute forms.
Tuberculosis of the testis and its appendages
Authors: Kulchavenya E. V. 
Published: August 2022

Tuberculosis of the genitourinary system has not lost its relevance. During the years of the pandemic of a new coronavirus infection, the number of newly diagnosed cases of tuberculosis of all localizations has decreased, but their structure has become more severe and mortality has increased. There is a wide variation in the statistics of urogenital tuberculosis (UGT) in the literature. The true incidence of scrotal tuberculosis is not known; at the end of the last century, it was believed that it was 7% of all cases of tuberculosis. It is believed that the share of isolated tuberculosis of the genital organs of men accounts for no more than 30% of all localizations of UGT, and most often tuberculosis develops in the epididymis. The spread of M. tuberculosis to the organs of the scrotum, as a rule, occurs by the hematogenous route from the primary focus in the lungs or kidney. However, the infection can also spread retrogradely from the prostate and seminal vesicles to the epididymis and testicles. Tuberculosis of the testis and its epididymis is often complicated by infertility and the formation of fistulas. This disease has no pathognomonic symptoms. Differential diagnosis is carried out between tuberculous epididymo-orchitis, testicular tumor, testicular torsion, bacterial epididymo-orchitis. Ultrasound examination is of great diagnostic value in tuberculosis of the scrotal organs. The ultrasound picture in tuberculosis of the testis and its epididymis is divided into 4 types: diffuse enlargement, heterogeneous hypoechogenicity; diffuse increase, uniform hypoechogenicity; nodular enlargement, heterogeneous hypoechogenicity; miliary dissemination. The world literature does not describe an example of tuberculosis of the scrotal organs, when the disease would be diagnosed during the patient’s initial visit to the doctor. As a result of late diagnosis or low suspicion for TB, up to 70% of patients undergo unnecessary surgery, although TB orchiepididymitis can be treated medically. The lecture also analyzed a number of clinical observations.
The Effects of Cognitive Bias on Fraud Examiner Judgments and Decisions
Authors: Brody Richard G. , DeZoort F. Todd , Gupta Gaurav , Hood Michael Bret 
Published: August 2022

ABSTRACT
This paper evaluates the effects that cognitive bias can have on fraud examiner judgment and decision-making. We draw on extant literature in accounting, auditing, and psychology to describe 11 specific biases that can undermine fraud examiner performance. Specifically, we use real-world examples from highly experienced anti-fraud professionals to consider each distinct bias given the unique engagement objectives, methods, relationships, and standards of evidence found in fraud examinations. We then discuss specific avoidance and mitigation strategies that fraud examiners can use to manage cognitive bias effects and improve their judgments and decisions. We conclude by suggesting the need for initial and continuing education in the area for professionals and future research to increase understanding in the area.
Long-term follow-up implant site development in the submerged mandibular primary second molars: a case report
Authors: Oh Min-Hee , Park Ae-Hyun , Yun Kwi-Dug , Kook Min-Suk , Cho Jin-Hyoung 
Published: August 2022

ABSTRACT
Treatment of ankylosed and submerged primary molars without permanent successors is challenging, as normal vertical dentoalveolar growth is compromised. Thus, grafting techniques and distraction osteogenesis are performed for ridge augmentation before implant restoration. However, these techniques are invasive with limited success. Another treatment for implant site development is noninvasive forced eruption. This case report describes long-term follow-up of alveolar ridge augmentation in the submerged mandibular primary second molars using subluxation and orthodontic forced eruption for implant site development. A 19-year old female had Class II molar relationships, upper anterior crowding with large overjet, missing four second premolars and submerged mandibular primary second molars with inadequate vertical development of alveolar bone. For the vertical alveolar bone alterations in the mandible, forced eruption with subluxation of ankylosed lower primary second molars was applied. Treatment outcome was evaluated over 5 years with stable occlusion, healthy periodontal tissues, and successful radiographic results.
Peran Pola Asuh Otoriter Demokratis, Dukungan Sosial, Kepercayaan Diri Terhadap Prestasi Atlet Renang Melalui Mediator Motivasi Berprestasi
Authors: Supriyanto Agus 
Published: August 2022

Penelitian ini bertujuan untuk menguji model teoritik peran pola asuh otoriter demokratis, dukungan sosial, kepercayaan diri terhadap prestasi atlet renang melalui mediator motivasi berprestasi fit dengan data empirik. Variabel penelitian ini terdiri dari variabel eksogen pola asuh otoriter demokratis, dukungan sosial dan kepercayaan diri, variabel endogen prestasi atlet renang dan variabel mediator motivasi berprestasi. Hipotesis penelitian ini adalah model teoritik yang menggambarkan mengenai peran pola asuh otoriter demokratis, dukungan sosial, kepercayaan diri terhadap prestasi atlet renang melalui mediator motivasi berprestasi fit dengan data empirik. Populasi penelitian ini adalah 362 atlet renang DIY yang mengikuti perlombaan renang Dolphin Cup ke IV Jateng-DIY tahun 2012. Teknik pengambilan sampel menggunakan purposive sampling, Sampel dalam penelitian ini adalah 103 atlet. Pengumpulan datanya menggunakan skala dan dokumentasi. Analisis datanya menggunakan program SmartPLS untuk menguji kesesuaian model pengukuran dengan data yang ada di lapangan. Hasil pengujian menunjukkan nilai Goodness of Fit (GoF): sebesar 0,679 sehingga dapat disimpulkan bahwa model teoritik yang menggambarkan mengenai peran pola asuh otoriter demokratis, dukungan sosial, kepercayaan diri terhadap prestasi atlet renang melalui mediator motivasi berprestasi fit dengan data empirik. Hasil pengujian menunjukkan bahwa pola asuh otoriter demokratis, dukungan sosial, kepercayaan diri berperan secara langsung, positif dan signifikan terhadap prestasi atlet renang serta ada peran yang signifikan pola asuh otoriter demokratis, dukungan sosial, kepercayaan diri terhadap prestasi atlet renang melalui mediator motivasi berprestasi. Pola asuh otoriter demokratis mempunyai sumbangan paling besar terhadap prestasi atlet renang nomor 50 meter dan 100 meter gaya bebas dibandingkan, dukungan sosial dan kepercayaan diri.