bluuebunny/crossref_metadata_2025_split huggingface dataset:
Irrigation Management of HLB-Affected Trees
Authors: Kadyampakeni Davie Mayeso , Morgan Kelly T. , Zekri Mongi , Ferrarezi Rhuanito , Schumann Arnold W. 
Published: February 2022

Water is a limiting factor in Florida citrus production during the majority of the year because of the low water holding capacity of sandy soils resulting from low clay and the non-uniform distribution of the rainfall. In Florida, the major portion of rainfall comes in June through September. However, rainfall is scarce during the dry period from February through May, which coincides with the critical stages of bloom, leaf expansion, fruit set, and fruit enlargement. Irrigation is practiced to provide water when rainfall is not sufficient or timely to meet water needs. Proper irrigation scheduling is the application of water to crops only when needed and only in the amounts needed; that is, determining when to irrigate and how much water to apply. With proper irrigation scheduling, yield will not be limited by water stress. With citrus greening (HLB), irrigation scheduling is becoming more important and critical and growers cannot afford water stress or water excess. Any degree of water stress or imbalance can produce a deleterious change in physiological activity of growth and production of citrus trees. The number of fruit, fruit size, and tree canopy are reduced and premature fruit drop is increased with water stress. Extension growth in shoots and roots and leaf expansion are all negatively impacted by water stress. Other benefits of proper irrigation scheduling include reduced loss of nutrients from leaching as a result of excess water applications and reduced pollution of groundwater or surface waters from the leaching of nutrients. Recent studies have shown that for HLB-affected trees, irrigation frequency should increase and irrigation amounts should decrease to minimize water stress from drought stress or water excess, while ensuring optimal water availability in the rootzone at all times.
Persepsi Kecemasan Ibu Terhadap Keterlambatan Imunisasi Bayi Di Pelayanan Kesehatan Pada Masa Pandemi Covid-19 Di Kota Medan
Authors: Purnama Tri Bayu , Ramadhani Fauziah , Harahap Fatimah Zahro , Lubis Ridha Roihan 
Published: February 2022

Pandemi COVID-19 berdampak pada kondisi
pelaksanaan
pelayanan imunisasi di posyandu, puskesmas, serta di
beberapa faskes
lainnya termasuk swasta.
Banyak dari
petugas kesehatan
yang
masih ragu-ragu untuk melakukan penyelenggara
a
n maupun sosialisasi pelayanan imunisasi pada masa COVID-19
dikarenakan adanya ketidaktahuan
serta tidak
adanya pedoman pelaksanaan imunisasi yang ada. Penelitian ini menggunakan pendekatan kualitatif untuk menggali persepsi dan respon ibu yang memiliki anak terhadap kecemasan pelayanan imunisasi di fasilitas pelayanan kesehatan. Terdapat 10 orang ibu (responden) yang diwawancara dengan kuesioner penelitian beserta pendalaman persepsi dan respon ditiap pertanyaan. Sebanyak 5 informan berusia 27 dan 28 tahun dengan 6 bayi tidak mengalami keterlambatan imunisasi dan 4 bayi lagi mengalami keterlambatan imunisasi. Alasan bayi terlambat imunisasi diantaranya karena bayi sakit ketika akan diimunisasi dan juga karena adanya pandemi COVID-19 yang membuat tempat pelayanan imunisasi seperti klinik, praktek bidan hingga rumah sakit tidak melayani imunisasi. Penerapan protokol kesehatan yang baik dalam pencegahan COVID-19 menjadi penting dalam akselerasi imunisasi pada masa pandemi
Literatur Review: Perbandingan Hasil Diagnosis Laboratorium IgM, IgG SARS-CoV-2 Metode ELISA Dan ICT
Authors: Farida Nada 
Published: February 2022

Background: The use of COVID-19 test kit depends on the sensitivity and specificity to detect and provide an accurate COVID-19 diagnosis. Currently, there are many serology tests detecting Antibody of SARS-CoV-2, that the evidence for its accuracy is still being studied through various evidence research. Purpose: Compare the sensitivity and specificity of the ELISA and ICT method for IgM, IgG SARS-CoV-2 detection. Method : literature review with Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) statement guideline. 10 out of 176 studies were obtained from searches which are carried out in PubMed, Science Direct and Google Scholar between October and December 2020. Articles were independently screened by title, abstract and full-text using the PICOS framework and critically appraised using JBI Critical Appraisal Tools. Findings were descriptively analyzed. Result : , Comparison of ELISA and ICT sensitivity in detecting IgM, IgG SARS-CoV-2 was 76,3%, 77,3% and ICT method : 53,9%, 64,8%. While the specificity of the ICT method was 96,2%, 98,1% and ELISA method : 94%, 97,1%. Conclusion: The sensitivity of IgM, IgG SARS-CoV-2 detection using ELISA method was higher than the ICT method. Conversely, the specificity of the ICT method (97.1%) is higher than the ELISA method (95.5%)
Hubungan Aktivitas Fisik Terhadap IMT Mahasiswa FKM Universitas Mulawarman Selama Pandemi Covid-19
Authors: Mifthahul Jannah Mifthahul 
Published: February 2022

Background: Since restrictions of public activity were implemented to prevent Covid-19 spreading, it also limited physical activity. Low physical activity is a risk factor for various comorbidities such as obesity, diabetes, hypertension which made more susceptible to severe Covid-19 disease. Purpose: To determine the association between physical activity and body mass index in Mulawarman University, Faculty of Public Health students during the Covid-19 pandemic. The study used an observational method with cross-sectional design with 197 sample. The instrument used Global Physical Activity Questionnaire (GPAQ) from WHO, collected by online questionnaire and analyzed using a chi-square test. Results: The mean of physical activity was 1498.23 MET (Metabolic Equivalent) and dominated by moderate activity (brisk walking, mopping floors, cleaning the house, moving furniture, gardening, planting trees, washing motorbikes or cars) the nutritional status dominated by normal nutritional status (60.4%) but there were still (4,6%) underweight and (10,2%) obesity. Based on the results of the Chi-square test, it showed an association between physical activity and body mass index p-value = 0.048. Conclusion: It could be concluded that there was an association between physical activity and body mass index in Mulawarman University Faculty of Public Health students during the Covid-19 pandemic
HUBUNGAN KADAR KOLESTEROL DENGAN TEKANAN DARAH PADA PEKERJA DI PT.X TAHUN 2020
Authors: Yusvita Fierdania , Handayani Putri , . Amaliah 
Published: February 2022

<p>Kadar kolesterol memegang peranan penting terhadap tekanan darah. Semakin tinggi kadar kolesterol maka akan semakin tinggi pula proses berlangsungnya aterosklerosis dalam pembuluh darah. Hal ini dapat menyebabkan elastisitas pembuluh darah berkurang dan jika terjadi terus menerus dapat menyebabkan hipertensi. Penelitian ini bertujuan untuk mengetahui hubungan kadar kolesterol total dengan tekanan darah pada pekerja di PT. X Tahun 2020. Jumlah responden adalah 97 orang. Disain penelitian ini bersifat deskriftif analitik dengan rancangan <em>cross sectional. </em>Pengambilan data merujuk pada hasil <em>Medical Check Up</em> pekerja di PT.X. Analisis data menggunakan uji korelasi pearson. Hasil penelitian menunjukkan ada hubungan antara kadar kolesterol dan tekanan darah, dengan p <em>value</em> = 0,002 dan nilai korelasi (r) = 0,649 (untuk tekanan darah sistolik) an p <em>value</em> = 0,001 dan r = 0,768 (untk tekanan darah diastolik) yang tergolong sangat kuat. Perlunya penerapan <em>health risk assessment</em> dengan langkah lengkap mulai dari identifikasi faktor resiko hiperkolesterol sebagai penyebab hipertensi, analisis dan pembuatan program pencegahan serta pengendalian perilaku hidup sehat pada pekerja di PT.X sehingga tidak menghambat produktivitas pekerja maupun industri.</p><p> </p><strong>Kata kunci</strong> : Kadar kolesterol, Tekanan Darah, Pekerja, Hipertensi
PERBEDAAN EFEKTIVITAS PENDIDIKAN KESEHATAN ANTARA MEDIA VIDEO DAN MEDIA LEAFLET TERHADAP PENINGKATAN PENGETAHUAN DAN SIKAP PENCEGAHAN COVID-19 DI MAN 1 PANDEGLANG TAHUN 2021
Authors: Ramdaniati Siti Nur , Wandi Somantri Ucu 
Published: February 2022

<p>Pandemi <em>Covid-19</em> yang awal kemunculannya di China pada akhir tahun 2019 sampai saat ini jumlah kasusnya masih terus bertambah di seluruh dunia, tidak terkecuali di Indonesia. Sejak terdeteksi kasus pertama pada bulan Maret 2020 sampai saat ini penambahan kasus masih terjadi hampir di seluruh kabupaten/kota di Indonesia. Tercatat sudah belasan ribu jiwa yang meninggal dunia akibat <em>Covid-19</em> di Indonesia. Selain itu juga pandemi Covid-19 telah memporak- porandakan perekonomian dunia khususnya Indonesia. Hal ini harus segera ditangani dengan segera dan tepat agar penularan Covid-19 di masyarakat dapat segera terkendali. Tujuan dari penelitian ini adalah untuk mengetahui Perbedaan Efektivitas Pendidikan Kesehatan Antara Media Video Dan Media Leaflet Terhadap Peningkatan Pengetahuan dan Sikap Pencegahan <em>Covid-19 </em>di MAN 1 Pandeglang Tahun 2020. Penelitian ini menggunakan rancangan quasi eksperimental dengan rancangan penelitian yang digunakan adalah <em>Pre test and Post tes two group. </em>Sebanyak 240 subjek yang diambil dari MAN 1 Pandeglang<em>, </em>117 siswa sebagai kelompok penyuluhan menggunakan media video dan 117 siswa sebagai kelompok penyuluhan menggunakan media <em>leaflet</em>. Masing-masing kelompok diberi kuesioner <em>pretest</em>. Selanjutnya, diberi eksperimen/intervensi penyuluhan, kemudian diberikan kuesioner <em>posttest</em>. Analisis data masing-masing kelompok dengan uji t-berpasangan dan uji <em>wilcoxon</em>. Sedangkan analisis data antar kelompok dengan uji t-tidak berpasangan. . Berdasarkan analisis bivariat hasil uji statistik pada kelompok video didapatkan <em>p-value</em> 0,008 untuk pengetahuan dan <em>p-value</em> 0,315 untuk sikap. Maka dapat disimpulkan bahwa ada pengaruh penyuluhan dengan video dalam peningkatan pengetahuan responden. Pada kelompok leaflet didapatkan <em>p-value</em> 0,000 untuk pengetahuan dan didapatkan nilai 0,048 untuk sikap. Maka dapat disimpulkan bahwa ada pengaruh penyuluhan dengan media leaflet terhadap peningkatan pengetahuan dan sikap tentang <em>Covid-19</em>. Kesimpulan penelitian ini adalah ada perbedaan efektifitas pendidikan kesehatan dengan media video dan leaflet dalam meningkatkan pengetahuan siswa MAN 1 Pandeglang.</p>
Perencanaan Desa Wisata Rindu Hati Bengkulu Tengah
Authors: Urmila Monica , Abdullah Ilham , Gusti Ririn 
Published: February 2022

Keberhasilan desa wisata tidak terlepas dari adanya suatu perencanaan yang baik dan sistematis. Perencanan yang baik dimulai dengan adanya tujuan dan target yang mesti dicapai kedepannya, merumuskan strategi berdasarkan tujuan, menentukan sumber daya manusia yang tepat, dan menentukan indikator keberhasilan seperti apa yang akan dicapai. Penelitian ini bertujuan untuk mendapatkan informasi secara detail yang berkaitan dengan Perencanaan Desa Wisata Rindu Hati Kabupaten Bengkulu Tengah. Penelitian dilakukan dengan menggunakan metode kualitatif. Data yang dikumpulkan menggunakan teknik wawancara, observasi dan dokumentasi. Dari perencanaan yang dilakukan dapat disimpulkan bahwa perencaan desa wisata rindu hati memiliki tujuan agar bisa menjadi desa wisata maju, go internasional, mampu membantu perekonomian masyarakat, dan menciptakan lapangan kerja. Strategi yang dilakukan yakni selalu melakukan perbaikan dan pembenahan, menjalin kerjasama dengan pihak ketiga dan promosi wisata melalui instagram dan facebook. Penentuan sumber daya manusia hanya berasal dari desa Rindu Hati saja dan tidak ada paksaan bagi yang ingin bergabung. Indikator keberhasilan dari perencanan ini apabila masyarakat desa wisata Rindu Hati ini masyarakatnya bertambah pendapatannya serta merasakan manfaat dari adanya desa wisata ini.
Picomolar Sensitivity Analysis of Multiple Bradykinin-Related Peptides in the Blood Plasma of Patients With Hereditary Angioedema in Remission: A Pilot Study
Authors: Marceau François , Rivard Georges-Etienne , Hébert Jacques , Gauthier Julie , Bachelard Hélène , Gangnus Tanja , Burckhardt Bjoern B. 
Published: February 2022

BackgroundHereditary angioedema (HAE) is a rare autosomal dominant disease; the most well understood forms concern the haplodeficiency of C1 esterase inhibitor (C1INH) and a gain of function mutation of factor XII (FXII). The acute forms of these conditions are mediated by an excessive bradykinin (BK) formation by plasma kallikrein.MethodsA validated LC-MS/MS platform of picomolar sensitivity developed for the analysis of eleven bradykinin-related peptides was applied to the plasma of HAE-C1INH and HAE-FXII sampled during remission.ResultsIn HAE-C1INH plasma, the concentrations of the relatively stable BK1−5 fragment (mean ± S.E.M.: 12.0 ± 4.2 pmol/L), of BK2−9 (0.7 ± 0.2 pmol/L) and of the sums of BK and its tested fragments (18.0 ± 6.4 pmol/L) are significantly greater than those recorded in the plasma of healthy volunteers (1.9 ± 0.6, 0.03 ± 0.03 and 4.3 ± 0.8 pmol/L, respectively), consistent with the previous evidence of permanent plasma kallikrein activity in this disease. Kinin levels in the plasma of HAE-FXII patients did not differ from controls, suggesting that triggering factors for contact system activation are not active during remission.ConclusionBK1−5, BK2−9 and the sum of BK and its fragments determined by the sensitive LC-MS/MS technique are proposed as potential biomarkers of HAE-C1INH in remission while this was not applicable to HAE-FXII patients.
Laccase-Driven Transformation of High Priority Pesticides Without Redox Mediators: Towards Bioremediation of Contaminated Wastewaters
Authors: Vaithyanathan Vasanth Kumar , Vaidyanathan Vinoth Kumar , Cabana Hubert 
Published: February 2022

In this study, Pleurotus dryinus was grown on municipal biosolids (BS) as the substrate to produce laccase for the removal of pesticides (fungicides, herbicides, and insecticides) from wastewater. Among the various types of BS tested, sterilized biosolids were the most promising substrate for laccase production by P. dryinus with a maximal laccase activity (162.1 ± 21.1 U/g dry substrate), followed by hygenized biosolids (96.7 ± 17.6 U/g dry substrate), unsterilized biosolids (UBS) (31.9 ± 1.2 U/g dry substrate), and alkali-treated biosolids (8.2 ± 0.4 U/g dry substrate). The ultrasound-assisted extraction of this enzyme from fermented UBS was carried out with 0.1 M phosphate buffer at pH 7.0, which increased the enzyme activity of the crude extract by 30%. To test the catalytic potential of the biocatalyst in real matrices, 1 U/ml of recovered crude laccase extract was applied for 24 h for the removal of 29 pesticides (nine fungicides, 10 herbicides, and 10 insecticides) either separately or as a mixture from spiked biologically treated wastewater effluent. When treated with crude enzyme extract, high-priority herbicides metolachlor and atrazine were completely removed, while 93%–97% of the insecticides aldicarb, spinosad, and azinphos-methyl and up to 91% of kresoxim-methyl were removed. Promising results were obtained with BS-derived crude enzyme extract exhibiting improved pesticides removal, which may be due to the mediator effect resulting from the catalytic transformation of other molecules in the cocktail. The results demonstrated a promising integrated bioprocess for the removal of pesticides in wastewater using crude laccase obtained from BS.
Effects of Isometric Plantar-Flexion on the Lower Limb Muscle and Lumbar Tissue Stiffness
Authors: Chen Baizhen , Cui Shaoyang , Xu Mingzhu , Zhang Zhijie , Liu Chunlong 
Published: February 2022

Purpose: This study investigated the effects of isometric plantar-flexion against different resistances on the thoracolumbar fascia (TLF), erector spinae (ES), and gastrocnemius stiffness by shear wave elastography (SWE). The purpose was to explore the interaction between the lower limb muscle and lumbar tissue in the myofascial tensegrity network.Methods: Twenty healthy young female were recruited in this study. The stiffness of the TLF, ES, medial gastrocnemius (MG), and lateral gastrocnemius (LG) was measured by SWE under four isometric plantar-flexion resistance conditions. The resistance conditions involved 0% maximum voluntary isometric contraction (MVIC), 20% MVIC, 40% MVIC, and 60% MVIC.Results: There was a strong correlation between the stiffness change of MG and that of TLF (r = 0.768–0.943, p &lt; 0.001) and ES (r = 0.743–0.930, p &lt; 0.001), while it was moderate to strong correlation between MG and that of LG (r = 0.588–0.800, p &lt; 0.001). There was no significant difference in the stiffness between the nondominant and dominant sides of TLF and ES under the resting position (p &gt; 0.05). The increase in stiffness of the TLF, ES, MG, and LG, with MVIC percentage (p &lt; 0.05), and the stiffness of TLF and ES on the nondominant side is much higher than that on the dominant side.Conclusions: Our data shows that isometric plantar-flexion has a significant effect on the stiffness of the lumbar soft tissue and gastrocnemius. The gastrocnemius has a strong correlation with the stiffness changes of TLF and ES, which provides preliminary evidence for exploring the myofascial tensegrity network between the dorsal side of the lower limb muscle and lumbar tissue.
Association of the Serum Folate and Total Calcium and Magnesium Levels Before Ovarian Stimulation With Outcomes of Fresh In Vitro Fertilization Cycles in Normogonadotropic Women
Authors: Polzikov Mikhail , Blinov Dmitry , Barakhoeva Zarema , Vovk Lyudmila , Fetisova Yulia , Ovchinnikova Maria , Tischenko Marina , Zorina Irina , Yurasov Vasily , Ushakova Tatyana , Sergeyev Oleg 
Published: February 2022

BackgroundWomen of reproductive age are recommended to consume folic acid and other supplements before conception and during pregnancy. We aimed to investigate the association of the serum folate and total magnesium (Mg) and calcium (Ca) levels before ovarian stimulation with the outcomes of assisted reproductive technology (ART) in normogonadotropic women.MethodsWe used a subanalysis of data obtained from a multicentre, randomized prospective study (NCT03088137). A total of 110 normogonadotropic, non-advanced aged, non-obese women with tubal and/or male infertility factors were enrolled for the single fresh ovarian stimulation GnRH antagonist cycle. The main outcome measures were the total oocyte yield, mature oocytes, fertilization rate, biochemical, clinical pregnancy, and live birth. Multivariable generalized linear models adjusted for covariates were used with a Poisson distribution and the log link function for adjusted oocyte counts, and a binomial distribution and the log link function were used for adjusted clinical ART outcomes.ResultsThe medians (interquartile range (IQR)) were as follows: baseline serum folate, 20.55 ng/ml (10.8, 32.9); Mg, 19.4 mg/L (18.7, 20.7); Ca, 94 mg/L (91.2, 96.4); and Ca/Mg ratio, 4.78 (4.55, 5.02). Women with higher serum folate concentrations (Q4≥33.0 ng/ml) had significantly lower total numbers of oocytes retrieved (adjusted mean (95% CI) 9.2 (7.6-11.3) vs 12.9 (10.9-15.4, p-trend=0.006)) and lower odds ratios (ORs) (95% CI) of 0.12 (0.02, 0.79) for clinical pregnancy and 0.10 (0.01, 0.70) for live birth compared with women in the lowest quartile (&lt;10.8 ng/ml), all p-trend&lt;0.001. Women in the highest Ca/Mg ratio quartile (≥5.02) had ORs (95% CI) of 6.58 (1.31, 33.04) for biochemical pregnancy, 4.85 (1.02, 23.08) for clinical pregnancy and 4.07 (0.83, 19.9) for the live birth rate compared with women in the lowest quartile (&lt;4.55), all p-trend&lt;0.001.ConclusionsUsing multivariable models, we suggested that a baseline elevated serum folate level (≥33.0 ng/ml) and a lower Ca/Mg ratio were associated with worse ART outcomes in normogonadotropic women. Our findings might be useful for choosing safe dosages of folate, calcium, magnesium and complex supplementation for both fertile women and women undergoing infertility treatment. Further preconception large-scale studies with known micro- and macronutrient statuses of both parents and serum folate, Ca, Mg, and hormone levels, are needed.
Coffee Types and Type 2 Diabetes Mellitus: Large-Scale Cross-Phenotype Association Study and Mendelian Randomization Analysis
Authors: Wang Xinpei , Jia Jinzhu , Huang Tao 
Published: February 2022

PurposeTo explore whether coffee intake is associated with the risk of type 2 diabetes mellitus (T2DM) from a genetic perspective, and whether this association remains the same among different types of coffee consumers.MethodsWe utilized the summary-level results of 12 genome-wide association studies. First, we used linkage disequilibrium score regression and cross-phenotype association analysis to estimate the genetic correlation and identify shared genes between coffee intake and T2DM in addition to some other T2DM-related phenotypes. Second, we used Mendelian randomization (MR) analysis to test whether there is a significant genetically predicted causal association between coffee intake and the risk of T2DM or other T2DM-related phenotypes. For all the analyses above, we also conducted a separate analysis for different types of coffee consumers, in addition to total coffee intake.ResultsGenetically, choice for ground coffee was significantly negatively associated with the risk of T2DM and some other related risks. While coffee intake and choice for decaffeinated/instant coffee had significant positive correlation with these risks. Between these genetically related phenotypes, there were 1571 genomic shared regions, of which 134 loci were novel. Enrichment analysis showed that these shared genes were significantly enriched in antigen processing related biological processes. MR analysis indicated that higher genetically proxied choice for ground coffee can reduce the risk of T2DM (T2DM: b: -0.2, p-value: 4.70×10-10; T2DM adjusted for body mass index (BMI): b: -0.11, p-value: 4.60×10-5), and BMI (b: -0.08, p-value: 6.50×10-5).ConclusionsCompared with other types of coffee, ground coffee has a significant negative genetic and genetically predicated causal relationship with the risk of T2DM. And this association is likely to be mediated by immunity. The effect of different coffee types on T2DM is not equal, researchers on coffee should pay more attention to distinguishing between coffee types.