bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cold storage effects on lethal and sublethal responses of Amphibalanus amphitrite Nauplii
Authors: Piazza Veronica , Gambardella Chiara , Costa Elisa , Miroglio Roberta , Faimali Marco , Garaventa Francesca 
Published: July 2022

AbstractBioassays are extensively used in ecotoxicology and there is a constant need for even more sensitive, reliable and easy to rear and obtain model organisms. Larvae of the crustacean Amphibalanus amphitrite are a good ecotoxicological model, for their high sensitivity to a wide range of toxicants and emerging contaminants. A standardized protocol for this toxicity bioassay has been recently proposed. Nevertheless, a limit of this model organism is the lack of resting stages and the need to use larvae immediately after their release from adults, thus increasing laboratory efforts related to the maintenance of adults. The aim of this work is to verify if short-term cold storage of A. amphitrite larvae prior to use in ecotoxicological tests may affect the ecotoxicological responses of these organisms. Three end-points (mortality, immobilization and swimming speed alteration) were measured on nauplii after storing them at 4 ± 1 °C for different times (24, 72 and 120 h) before bioassay set-up. Bioassays were set up using: (i) clean filtered natural sea water (0.22 µm FNSW), (ii) a reference toxicant (Cadmium Nitrate) and (iii) an environmental matrix (sediment elutriate). Results show that mortality, differently from the other two endpoints, was not affected by cold-storage. Even after 5 days of larvae storage at 4 ± 1 °C before bioassay set up, mortality data were comparable to those obtained for non-cold-stored organisms. Moreover, larval sensitivity to the reference toxicant and sediment elutriate did not change. Regarding the other two end points, low cadmium concentrations significantly changed immobility and swimming activity in cold-stored nauplii compared to larvae used immediately after larval release. In conclusion, short-term cold storage of A. amphitrite nauplii before bioassay set up is an appropriate procedure in ecotoxicological testing if mortality is the endpoint to be considered for final evaluation.
Ecotoxicological impacts of industrial effluents on irrigation water quality, animal health and the role of calcium alginate in effluents treatment
Authors: Zeid Hanaa Abdel Atty , El-Zayat Moustafa Mohsen , Abdrabouh Abeer El-Said 
Published: July 2022

AbstractThe effluents discharged from Mansoura Company for Resins and Chemicals Industry were evaluated for drinking and irrigation purposes. Calcium-alginate beads were used for effluents treatment in this study. Young male rats were also allowed to drink effluents at different concentrations (10%, 50%, 100%) and treated 100% effluents with calcium-alginate for 11 weeks. Results indicated high concentrations of some physicochemical parameters and Cd, Co, Fe, Mn, Ni, Pb, and Zn in effluents that exceeded the permissible limits for drinking and irrigation purposes. Treatment by calcium-alginate alleviate heavy metals concentration but did not affect the physicochemical parameters. Depending on effluents concentration, the liver of young male rats showed high accumulation of Fe, Mn, Zn, Pb, Cd, Co, Cu, Cr, and Ni compared to the control group. Serum levels of liver enzymes, total bilirubin significantly increased while total protein, and albumin contents decreased in effluent groups. Liver concentrations of malondialdehyde and protein carbonyl significantly elevated along with significant decrease in superoxide dismutase, catalase, glutathione-S-transferase activities, and glutathione content. Moreover, growth and thyroid hormones were significantly reduced along with significant elevation in thyroid stimulating hormone. This was accompanied by significant decrease in the body weight, especially with 100% effluents concentration compared to control group. Also, histological investigations of both liver and thyroid gland using hematoxylin and eosin showed distortion in the structure of both organs especially with 50% and 100% effluent groups. However, treatment of effluents by calcium-alginate improved these changes. The study revealed that calcium-alginate are effective biosorbents for heavy metals and consequently decrease animal and human health hazards, but further studies are needed to alleviate physicochemical characteristics.
Curricular integration of academic and vocational education: a theory-based empirical typology of dual study programmes in Germany
Authors: Mordhorst Lisa , Jenert Tobias 
Published: July 2022

Abstract
In Germany, dual learning programmes are increasingly offered by higher education institutions. These programmes’ main characteristic and greatest challenge is their integration of academic and vocational learning. So far, this challenge has frequently been stated without specifying its exact nature and consequences for learners. The present study addresses this pedagogical research gap and examines the extent of variation in the degree of integration among dual study programmes. With reference to curriculum theory, the study develops an empirical typology of curricular integration in dual programmes. The data sample consists of 152 programmes at (dual) universities and universities of applied sciences. Data is analysed using hierarchical cluster analysis. Results indicate that the currently prevailing forms of curricular integration should best be differentiated according to five types. The five overlapping types of integration are located on a continuum ranging from parallelism through organisational linking to full curricular integration targeted immediately at students’ personal integration. The analysis confirms that there are problems with complying with integration standards set on the policy level. Above all, the study offers new insights on what marks the diverse integration landscape of dual study programmes. It proves that approaches to integration are more differentiated than previous research has shown.
Precise Cable-Suspended Pick-and-Place with an Aerial Multi-robot System
Authors: Jiménez-Cano A. E. , Sanalitro D. , Tognon M. , Franchi A. , Cortés J. 
Published: July 2022

AbstractThis work introduces the G-Fly-Crane, a proof-of-concept aerial multi-robot system designed to demonstrate the advantage of using multiple aerial robots as a valuable tool for novel construction techniques, not requiring the use of heavy engines and costly infrastructures. We experimentally demonstrate its capability to perform pick-and-place and manipulation tasks in a construction scenario, with an increased payload capacity and dexterity compared to the single robot case. The system is composed of three aerial robots connected to a platform by three pairs of cables. The platform is equipped with a gripper, enabling the grasping of objects. The paper describes in detail the hardware and software architecture of our prototype and explains the implemented control methods. A shared control strategy incorporates the human operator in the control loop, thus increasing the overall system reliability when performing complex tasks. The paper also discusses the next steps required to bring this technology from indoor laboratory conditions to real-world applications.
High degree of N-functionalization in macroscopically assembled carbon nanotubes
Authors: McGlynn Ruairi J. , Brunet Paul , Chakrabarti Supriya , Boies Adam , Maguire Paul , Mariotti Davide 
Published: July 2022

AbstractNitrogen doping of carbon nanomaterials has emerged as a method to develop novel material properties, though limitations in the form of extended treatment times, harsh chemical usage and limited total nitrogen content exist. Here, macroscopic ribbon-like assemblies of carbon nanotubes are functionalized with nitrogen using a simple direct current-based plasma–liquid system. This system utilizes the plasma-generated species in an ethanol:water solution with ethylenediamine as a nitrogen precursor for the nitrogen functionalization of the carbon nanotube assembly. These unique, plasma-generated species and pathways enable rapid and high levels of functionalization with the atomic concentration of nitrogen reaching 22.5%, with amine groups, pyrrolic groups and graphitic nitrogen observed in the X-ray photoelectron spectra, the highest ever achieved. This nitrogen content is demonstrated to be significantly higher than a comparative electrolysis process. This demonstrates that this plasma process enhances the availability of nitrogen from the ethylenediamine precursor, facilitating greater functionalization.
Graphical abstract
Influence of carbon on the formation of γ/γ′ microstructure and κ-phase in the WC/Co–Ni–Al–W system: ab initio calculations and experimental studies
Authors: Wolf Maximilian , Edtmaier Christian , de Oro Calderon Raquel 
Published: July 2022

AbstractModifications of the binder phase (γ) of cemented carbides have the potential to increase the hardness and wear resistance of the whole material. Partially, coherent precipitations with L12 structure (γ’) promise these improved properties without sacrificing tensile strength or toughness. γ’ is a metastable phase in the Al–Co–W ternary system in the form of Co3(Al,W) which is stabilized by the substitution of cobalt with nickel. Superalloys of the composition Co–(30Ni)–9Al–7 W with different carbon contents were prepared by inductive melting, and the resulting microstructures were analysed using SEM–EDS, XRD and Vickers hardness. Cemented carbides with γ/γ’ binder microstructure were prepared via DTA, and the phase equilibria in the composite material were investigated experimentally and in silico. It was shown that nickel stabilizes the γ’ phase in superalloys as well as in cemented carbides. Carbon leads to the formation of an additional phase with E21 structure (κ). DTA measurements of cemented carbides with different aluminium–cobalt–nickel mixtures as binder gave an overview of the compositional influence. Enthalpies of formation for compounds with L12 and E21 structure were calculated using ab initio methods and compared to experimental results.
Graphical Abstract
Effect of hydrogen-related shallow donor on the physical and chemical properties of Ag-doped ZnO nanostructures
Authors: Al-Bataineh Qais M. , Ababneh Riad , Bahti A. , Bani-Salameh Areen A. , Tavares Carlos J. , Telfah Ahmad 
Published: July 2022

AbstractSilver-doped zinc oxide nanostructures (Ag/ZnO NSs) with Ag content of 0 wt%, 5 wt%, 10 wt%, and 20 wt% were synthesized using a hydrothermal technique. The prepared nanostructures were annealed at 500 °C for 2 h. The samples were characterized by using scanning electron microscopy, FTIR, X-ray diffraction (XRD), and electrical conductivity. FTIR spectra confirms the presence of hydrogen-related shallow donor defects in the Ag/ZnO NSs, which bind to the oxygen vacancy ($${\text{H}}_{\text{O}}$$

H
O

) and consequently plays a significant role in the physicochemical properties of the metal oxide nanostructures. The $${\text{H}}_{\text{O}}$$

H
O

defects are blended to O- and Zn-polar Ag-doped ZnO NSs, depending on their polarity. XRD results verified that Ag/ZnO NSs have a polycrystalline hexagonal structure. Williamson–Hall methods were used to estimate the microstructural properties of polycrystalline nanostructures. The electrical conductivity increased from 0.60 to 1.10 µS/cm, and the bandgap energy decreased from 3.36 to 3.10 eV by increasing the Ag from 0 wt% up to 20 wt%.
Does hyperbaric oxygen therapy pressure reduce mechanical stability of implants?
Authors: Özyurt Anıl 
Published: July 2022

AbstractHyperbaric oxygen therapy (HBOT) has beneficial effects for patients complaining of poor bone healing such as related to diabetes mellitus. However, it is known that changing pressure conditions might cause dental barotrauma in the oral cavity. The aim of this study was to evaluate implant mechanical stability under HBOT pressure. Thirty-five implants were placed in bone blocks divided into five groups as control, 1, 3, 5, 7 HBOT cycles. In one cycle, 2.4 bar 100% oxygen pressure was performed. Implants’ stabilities were measured with resonance frequency analysis (RFA) and removal torque (RT) meter device. Data were analyzed using Shapiro Wilk, ANOVA, and Tukey HSD tests for RFA and RT values considering p < 0.05 as the statistical significance level. RFA and RT values were compared by Pearson correlation coefficiency. RFA values of 5 and 7 HBOT cycles were significantly lower than 1, 3 HBOT and control group (p < 0.001). There was no statistical difference between 5 and 7 HBOT cycles RFA values. HBOT pressure simulation slightly but statistically decreased the stability for the implants exposed to 5 and 7 HBOT cycles.
The Development of Gender Role Attitudes During Adolescence: Effects of Sex, Socioeconomic Background, and Cognitive Abilities
Authors: Ullrich Ricarda , Becker Michael , Scharf Jan 
Published: July 2022

AbstractHow gender role attitudes develop during adolescence, and how biological, social, and cognitive factors predict this development, remains a matter of debate. This study examines the development of gender role attitudes from early adolescence to emerging adulthood and investigates how the developmental trajectory is affected by sex, socioeconomic status, and cognitive abilities (intelligence). Four waves of the large-scale longitudinal German dataset BIJU between 1991 (grade 7; N = 3828, Mage = 13, SD = 0.61, 53.1% female, 96.4% German nationality), 1995 (grade 10, Mage = 17), 1997 (grade 12, Mage = 19) and 2001/2002 (university/career entry, Mage = 24) were used. Measurement invariance was examined across waves and gender. Latent growth curve models showed that adolescents developed more egalitarian gender role attitudes. Differences between the sexes decreased over time but remained significant. Socioeconomic status seemed less relevant, while adolescents, especially those with lower intelligence scores, developed more egalitarian gender role attitudes during adolescence. The results showed that teenagers developed more open and egalitarian attitudes during adolescence, and that the development trajectories of female and male adolescents converge.
Drug-related emergency department visits in older patients: an applicability and reliability study of an existing assessment tool
Authors: Kempen Thomas Gerardus Hendrik , Hedman Anton , Gillespie Ulrika 
Published: July 2022

Abstract
Background
AT-HARM10 is a research tool to identify possible drug-related hospital admissions. It is unclear whether the tool can be applied to emergency department visits as well.

Aim
The aim of this study was to investigate the applicability and reliability to identify drug-related emergency department visits in older patients with AT-HARM10.

Method
A random sample of 400 patients aged 65 years or older from a clinical trial in four Swedish hospitals was selected. All patients’ emergency department visits within 12 months after discharge were assessed with AT-HARM10. The main outcome measures were the percentage of successfully assessed visits for applicability and the interrater reliability (Cohen’s kappa).

Results
Of the initial sample (n = 400), 113 patients [median age (interquartile range): 81 (76–88) years] had at least one emergency department visit within 12 months. The patients had in total 184 visits, of which 179 (97%) were successfully assessed. Fifty-three visits (29%) were possibly drug-related. The Cohen’s kappa value was 0.70 (substantial).

Conclusion
It seems applicable and reliable to identify possible drug-related emergency department visits in addition to hospital admissions in older patients with AT-HARM10. As a consequence, the tool has been updated to support its novel use in clinical research.
Phenomenological explanation: towards a methodological integration in phenomenological psychopathology
Authors: Summa Michela 
Published: July 2022

AbstractWhether, and in what sense, research in phenomenology and phenomenological psychopathology has—in addition to its descriptive and hermeneutic value—explanatory power is somewhat controversial. This paper shows why it is legitimate to recognize such explanatory power. To this end, the paper analyzes two central concerns underlying the debate about explanation in phenomenology: (a) the warning against reductionism, which is implicit in a conception of causal explanation exclusively based on models of natural/physical causation; and (b) the warning against top-down generalizations, which neglect the specificity of the individual. While acknowledging that these two caveats express serious concerns regarding the debate on explanatory models, I show that phenomenology has the resources to respond to them. These can be found in analyses of different types of causation relating to different regions of reality and in the structure of explanatory models based on exemplarity. On the basis of these analyses, I defend a pluralist account vis-à-vis explanatory models.
Effect of foliar spraying of organic and inorganic selenium fertilizers during different growth stages on selenium accumulation and speciation in rice
Authors: Yuan Zhengqing , Long Weixiong , Liang Ting , Zhu Menghan , Zhu Aoyun , Luo Xiaoyun , Fu Lu , Hu Zhongli , Zhu Renshan , Wu Xianting 
Published: July 2022

Abstract
Aims
Most crops are supplemented with selenium (Se) through the exogenous addition of inorganic Se fertilizer. There is a lack of in-depth research on organic Se fertilizers. Meanwhile, the dosage range between human Se deficiency and Se toxicity is narrow, so the Se content of agricultural products needs to be controlled within a reasonable interval.

Methods
Se accumulation and speciation in rice were analyzed and compared during three different growth stages (late tillering stage, initiate heading stage, and full heading stage) using three Se fertilizers: selenite, fermented Se, and potassium selenocyanoacetate (Se-AAF) via the foliar application.

Results
The Se content in rice sprayed with organic Se fertilizer was controlled in the relatively safe range and met the human Se supplement requirement compared to the sprayed sodium selenite, which was too high of a dose. The percentage of organic Se and protein Se in brown rice was found to be similar in all three Se fertilizers. The highest organic Se content of 91.57% was found in the grain of rice at the full heading stage by spraying Se-AAF. The main Se species in the grain was selenomethionine (SeMet), which reached 80% of the total Se. Se-methyl selenocysteine(SeMeCys) was found only in Se-AAF. The grain quality showed that all three Se fertilizers increased the consistency of gelatinization.

Conclusions
Appropriately delaying the spraying time and selecting organic Se fertilizer as the Se source can help to produce green and safe selenium-rich rice.
A new era for oral peptides: SNAC and the development of oral semaglutide for the treatment of type 2 diabetes
Authors: Aroda Vanita R. , Blonde Lawrence , Pratley Richard E. 
Published: July 2022

AbstractGlucagon-like peptide-1 (GLP-1) receptor agonists (GLP-1RAs) were first introduced for the treatment of type 2 diabetes (T2D) in 2005. Despite the high efficacy and other benefits of GLP-1RAs, their uptake was initially limited by the fact that they could only be administered by injection. Semaglutide is a human GLP-1 analog that has been shown to significantly improve glycemic control and reduce body weight, in addition to improving cardiovascular outcomes, in patients with T2D. First approved as a once-weekly subcutaneous injection, semaglutide was considered an ideal peptide candidate for oral delivery with a permeation enhancer on account of its low molecular weight, long half-life, and high potency. An oral formulation of semaglutide was therefore developed by co-formulating semaglutide with sodium N-(8-[2-hydroxybenzoyl]amino)caprylate, a well-characterized transcellular permeation enhancer, to produce the first orally administered GLP-1RA. Pharmacokinetic analysis showed that stable steady-state concentrations could be achieved with once-daily dosing owing to the long half-life of oral semaglutide. Upper gastrointestinal disease and renal and hepatic impairment did not affect the pharmacokinetic profile. In the phase III PIONEER clinical trial program, oral semaglutide was shown to reduce glycated hemoglobin and body weight compared with placebo and active comparators in patients with T2D, with no new safety signals reported. Cardiovascular efficacy and safety are currently being assessed in a dedicated outcomes trial. The development of an oral GLP-1RA represents a significant milestone in the management of T2D, providing an additional efficacious treatment option for patients.
The model of maximum productivity for research universities SciVal author ranks, productivity, university rankings, and their implications
Authors: Demeter Marton , Jele Agnes , Major Zsolt Balázs 
Published: July 2022

AbstractAware of the growing importance of global rankings, universities aim to enhance their positions. However, the exact relation between research productivity and ranking positions is not fully understood in recruitment processes. Taking the field of communication as a case study, this paper analyzes the scholarly performances of 6291 faculty members from 172 QS top-ranked communication departments, and it also offers an experiment in which we tested top departments’ interest in recruiting a highly productive communication scholar. We found that while both departments and scholars are aware of the connection between productivity and excellence, there is still room for improvement. Even in the top ranked communication departments, there is a significant scarcity of best-performing scholars, but it is hard to employ a top scholar beyond the usual job posting methods. Contrary to the Standard Model of Productivity, whereby recruitment is based on assumptions and potential, we offer our Model of Maximum Productivity where both recruitment and assessments are based on scientometrics, productivity and evidence alone.
Searching for a Solar Source of Magnetic-Field Switchbacks in Parker Solar Probe’s First Encounter
Authors: de Pablos D. , Samanta T. , Badman S. T. , Schwanitz C. , Bahauddin S. M. , Harra L. K. , Petrie G. , Mac Cormack C. , Mandrini C. H. , Raouafi N. E. , Martinez Pillet V. , Velli M. 
Published: July 2022

AbstractParker Solar Probe observations show ubiquitous magnetic-field reversals closer to the Sun, often referred to as “switchbacks”. The switchbacks have been observed before in the solar wind near 1 AU and beyond, but their occurrence was historically rare. PSP measurements below ∼ 0.2 AU show that switchbacks are, however, the most prominent structures in the “young” solar wind. In this work, we analyze remote-sensing observations of a small equatorial coronal hole to which PSP was connected during the perihelion of Encounter 1. We investigate whether some of the switchbacks captured during the encounter were of coronal origin by correlating common switchback in situ signatures with remote observations of their expected coronal footpoint. We find strong evidence that timescales present in the corona are relevant to the outflowing, switchback-filled solar wind, as illustrated by strong linear correlation. We also determine that spatial analysis of the observed region is optimal, as the implied average solar-wind speed more closely matches that observed by PSP at the time. We observe that hemispherical structures are strongly correlated with the radial proton velocity and the mass flux in the solar wind. The above findings suggest that a subpopulation of the switchbacks are seeded at the corona and travel into interplanetary space.