bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pelvic lymph node dissection alone versus adjuvant radiotherapy in node positive penile cancer
Authors: Naushad Naufa , Deb Abdalla A. , Agag Ayman A. , Serag Hosam A. , Sangar Vijay K. 
Published: March 2022

Introduction:
The management options for regional lymph nodes (LNs) in men with penile cancer include surveillance, surgery, and chemotherapy. The use of radiotherapy (RT) for nodal disease follows tradition and single-institution policies. We aimed to analyse the existing evidence regarding the management of penile cancer patients with suspected or known metastatic pelvic LNs using pelvic LN dissection (PLND) with RT versus PLND or RT alone.

Methods:
A systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, with no filters for language or time. The search was conducted in EMBASE, MEDLINE/PubMed, and Cochrane Library. Inclusion criteria were adult men with penile cancer and suspected metastatic pelvic LNs, undergoing PLND with or without RT or RT alone. Primary outcomes included disease-specific survival and locoregional recurrence. Secondary outcomes included overall survival and complications of therapy.

Results:
A total of 552 articles were identified. Only eight retrospective studies were eligible for inclusion (including 406 patients). All studies had a high risk of bias. None of the studies reported the use of neoadjuvant RT. Indications for PLND varied but were usually two or more clinically positive inguinal nodes with or without extracapsular extension. Adjuvant RT was mainly used in positive pelvic LNs or pN2/pN3 stages. The rate of locoregional recurrence following adjuvant RT was 70%. Complications of treatment were reported in two studies only.

Conclusions:
There is insufficient evidence to recommend the use of adjuvant RT following PLND in penile cancer patients. The quality of evidence is low due to the retrospective design and high risk of bias. Randomized clinical trials are required to assess the efficacy and safety of adjuvant RT and PLND.
Fine-needle aspiration cytology of salivary gland lesions
Authors: Rameeza A , Hemalata M 
Published: March 2022

Background:
Fine-needle aspiration cytology (FNAC) is a sensitive, specific, cost-effective tool and has been widely used as a diagnostic tool for the management of various head-and-neck lesions. Salivary gland lesions constitute the most common head-and-neck lesions. These lesions can range from inflammatory to neoplastic, which can be either benign or malignant.

Materials and Methods:
The study was performed on 104 patients who presented with salivary gland swelling to the department of pathology at a tertiary care center from January 2016 to June 2020. FNAC was performed using a 22–24G needle, and smears were stained with Giemsa, hematoxylin and eosin and Papanicolaou stain. Histopathology was assessed on routine hematoxylin- and eosin-stained paraffin sections. The cytological and histopathological slides were studied, analyzed and correlated. Sensitivity, specificity, positive predictive value and negative predictive were calculated.

Results:
The study included 104 cases in the age range of 10–70 years and a mean of 45 years (±16 standard deviation). There was a male preponderance with a male-to-female ratio of 1.6:1. The parotid gland was the most common site 91 (87%). On cytology, 71 (68%) were neoplastic, of which 58 (81%) were benign and 13 (19%) were malignant. Histopathological correlation was available in 36 cases (50%), 24 (67%) of which were benign and the remaining 12 (33%) were malignant. The sensitivity, specificity, positive predictive value and negative predictive value of the present study are 95%, 85%, 91% and 92%, respectively.

Conclusion:
FNAC of the salivary gland is a safe, reliable and cost-effective technique which can be used as the first line of investigation in evaluating salivary gland lesions.
Upregulated expression of NOP2 predicts worse prognosis of gastric adenocarcinoma by promoting tumor growth
Authors: Feng Jingyu , Zhang Jing , Li Yang , Wang Jiguo , Mo Panyan , Lin Lizhu 
Published: March 2022

Background:NOP2 nucleolar protein plays a crucial role in early embryo development and cell proliferation. The role of NOP2 in human gastric adenocarcinoma has not been elucidated. In the present study, we aimed to examine the expression levels of NOP2 and dissected whether NOP2 expression was associated with aggressive clinicopathological outcomes of patients with gastric adenocarcinoma.Methods:Clinicopathological analysis was performed in patients with gastric adenocarcinoma. Expression of NOP2 was tested by immunohistochemistry staining and quantitative RT-PCR. The prognostic role of NOP2 in gastric adenocarcinoma patients was assessed by univariate and multivariate analysis. The effect of NOP2 on cell proliferation was examined through cellular experiments and mice models.Results:NOP2 expression was elevated in gastric adenocarcinoma tissues compared to normal gastric tissues. High expression of NOP2 was significantly correlated with tumor size, invasion depth, and lymph node metastasis. Moreover, patients with high NOP2 expression had poorer overall survival, and NOP2 was identified as an independent prognosis factor. Using the gastric adenocarcinoma cells, we found that NOP2 can promote tumor cell proliferation bothin vitroandin vivo.Conclusions:Overexpression of NOP2 significantly correlates with a poorer prognosis of gastric adenocarcinoma patients and suggested the potential of NOP2, which may serve as a novel prognostic biomarker in gastric adenocarcinoma.
Active Engagement of Private Healthcare Providers Is Needed to Propel Malaria Elimination in India
Authors: Rahi Manju , Sharma Amit 
Published: April 2022

ABSTRACT.
Malaria is a major public health concern in India. Despite a remarkable decline in overall malaria cases and deaths over the past several years, the caseload is still substantial. India’s commitment towards malaria elimination by 2030 requires several additional measures for its achievement. The country’s malaria data are collated from the public health sector only by the aggregated paper-based surveillance system, which is considered weak because it captures only a minuscule percentage (8% as per the World Malaria Report 2017). The absence of private-sector data is a serious caveat in India’s malaria epidemiological scenario. The private healthcare sector (trained and untrained) is a major provider to communities in malaria-endemic areas. It is increasingly recognized that the involvement of the private healthcare sector is crucial for understanding the complete epidemiological picture and targeting elimination strategies accordingly as is being done for tuberculosis in India. Active involvement and alignment of the private sector to the government program of the private sector can be fostered by assessing the presence of the private healthcare sector via landscaping exercise, establishing linkages between the two sectors, incentivization, and encouraging reporting via user-friendly online and offline systems. There are challenges and barriers to the successful adoption of the private healthcare providers in the fold of the national malaria control program; at the same time, it is a critical step that will propel malaria elimination plans of India.
The effect of advertising on the decision to purchase facial wash during the COVID-19 pandemic
Authors: Pradiningsih Anna , Nopitasari Baiq Leny , Melian Ida Ayu , Sukmaningsih Resi , Andanalusia Mahacita 
Published: March 2022

Background: During the COVID-19 pandemic, cleanliness became the main everyday concern, particularly facial hygiene. Nowadays, the public has more time to access media; thus, it is expected that promotional media strongly influence the decision to purchase a facial wash. Aim: To determine the effect of advertising on the purchasing behaviour of facial wash during the COVID-19 pandemic. Methods: This descriptive, observational, and cross-sectional research enrolled 100 students of different majors from the Muhammadiyah University of Mataram, Indonesia. It used the advertising (ad) effect questionnaire to evaluate three advertising indicators, i.e. ad information, ad criteria, and ad component. One-way ANOVA and Spearman Correlation Analysis were used to process the data. Results: The overall correlation coefficient was 0.018. The correlation coefficients of each indicator were 0.487 for ad information, 0.02 for ad criteria, and 0.0673 for ad components. Conclusion: The results revealed an effect of advertising on the decision to purchase facial wash during the COVID-19 pandemic.
Analysis on State of Mortgage Lending for 2016-2020 in the Republic of Kazakhstan
Authors: Abdizhapar Aiganym 
Published: March 2022

It is significant to resolve important socio-economic tasks such as increasing the availability of housing for the population, increasing the share of housing owners in order to stabilize society. To provide solutions, there is a necessity to form a market housing financing system that meets the competitive demand of the population for housing. The main directions of worldwide recognized long-term financing of housing construction are mortgage lending and the system of construction savings. Therefore, for Kazakhstan, the effective formation of the mortgage lending system is one of the priorities of housing policy. At the current stage of Kazakhstan's development, the mortgage lending system is the most important direction for the development of long-term housing financing. International experience depicts that the development of mortgage lending brings maximum benefits for the state and the country's economy as a whole. This is explained, first of all, by the fact that it affects problems of a housing nature and is quite significant on the part of the social policy of the state. Taking into account the multilateral socio-economic effect of the development of the mortgage lending system, this problem is presented as particularly relevant for Kazakhstan.
Moreover, it is essential to study the current results of the system over the past years and determine the level of development of the mortgage lending system in modern conditions to provide an analysis of the current state of mortgage lending in the country. The analysis of statistical data on the indicators of mortgage lending is carried out. The study encompasses the main issues related to the current state of mortgage lending in the Republic of Kazakhstan.
Competencias gerenciales y gestión pública: revisión sistemática
Authors: Vásquez Ortiz Jorge Alejandro 
Published: March 2022

Un aspecto clave que toda organización procura en la actualidad para tener éxito, es evitar errores en su proceso de toma de decisiones. Dicho proceso sólo es efectivo si se precisan, por un lado, los recursos adecuados a las metas planteadas por la organización y por el otro, competencias altamente evaluadas en el personal gerencial o directivo.
El propósito del presente trabajo, sustentado en un proceso de revisión sistemática, ha sido recabar información imparcial respecto a las competencias gerenciales vinculadas al proceso de toma de decisiones que repercuten en la Administración Pública.
Al respecto, se ha efectuado una revisión sistemática en Bases de Datos PROQUEST, EBSCO, SCIELO de artículos científicos del período comprendido entre 2020 a 2021, conforme a lo establecido en la Matriz PRISMA, considerando los siguientes criterios de inclusión: Texto completo en formato PDF, originales en español, francés, portugués o inglés, revisión de expertos, investigaciones cuantitativas y cualitativas, se han excluido los que eran similares a los que trataban el tema de gobernabilidad. La búsqueda se llevó a cabo utilizando las ecuaciones: “Mangerial competences” and “Public Management” OR “Managerial skills” and “Goverment” OR “Mangerial skills” and “Public Administration”, se incluyeron en total 36 artículos. Se encontró relación significativa entre Managerial Competences y Public Administration. Se evidencia la necesidad de realizar mayores estudios a fin de profundizar lo vertido en el presente artículo.
Condiciones laborales de la minería informal y su relación con la tuberculosis y la silicosis que padecen los obreros de la zona minera de Otoca – Lucanas Ayacucho – 2014
Authors: Loayza Gutiérrez Jessenia Leonor 
Published: March 2022

Objetivo: Determinar la relación que existe entre las condiciones laborales y los factores socio-demográficos con la tuberculosis y la silicosis en la población obrera de la zona minera de Otoca – Lucanas, Ayacucho – 2014. Métodos. Se realizó un estudio descriptivo transversal, yo La muestra estuvo constituida por 47 obreros de la zona minera de Otoca – Lucanas quienes aceptaron voluntariamente participar en el estudio. Se evaluaron las variables edad, sexo, estado civil, grado de instrucción, afiliación al seguro, equipo de protección personal y ambiente laboral, tuberculosis y silicosis. Resultados y discusión. La prevalencia de tuberculosis fue de 19,1%, la silicosis fue de 14,9%. Se halló edad y presencia de tuberculosis (0,046), no se halló asociación entre el sexo (0,482).
Conclusiones: Los factores socio-demográficos edad y estado civil presentan asociación con la presencia de silicosis en la población de estudio. El sexo, el grado de instrucción y las condiciones laborales no presentan asociación con la tuberculosis.
Influencia de la gestión educativa en la convivencia escolar de instituciones educativas–Huancavelica, Perú
Authors: Meza Huamani Senia Lilia , Chacaltana Huarcaya Raquel Elizabeth , Lopez Castillo Giuliana Melissa , Ochoa Carbajo Jesús Alberto , Jurado Enriquez Elizabeth Lizbel 
Published: March 2022

La presente investigación tiene como objetivo determinar en qué medida influye la gestión educativa en la convivencia escolar de las instituciones educativas de la red de Córdova, Huaytará-Huancavelica, 2014; y se planteó la hipótesis: La gestión educativa influye significativamente en la convivencia escolar.
La presente investigación es un estudio de tipo correlacional explicativo porque se analizan relaciones de covarianza y causalidad, con un diseño transeccional correlacional causal. La muestra estuvo integrada por 40 docentes de las instituciones educativas de la red de Córdova, Huaytará- Huancavelica. Los datos relacionados con las variables gestión educativa y convivencia escolar, con sus respectivas dimensiones, se obtuvieron mediante la aplicación de la técnica de la encuesta y sus instrumentos los cuestionarios de gestión educativa y convivencia escolar; luego se tabularon los datos utilizando medidas estadísticas para determinar en qué medida la gestión educativa influye en la convivencia escolar.
Los resultados obtenidos reflejan que existe una relación positiva entre las variables de estudio; es decir entre la gestión educativa y la conveniencia escolar con un coeficiente de correlación Pearson de 0,881 en los docentes de las Instituciones Educativas de la red de Córdova, Huaytará, 2014. La influencia de la gestión educativa en la convivencia escolar queda indicado por el coeficiente de determinación equivalente al 77.5% de los casos observados.
El rompecabezas del arte contemporáneo: Incertidumbres, novedad y aburrimiento
Authors: Chao-Yang Lee , Clemente Marco José Luis 
Published: March 2022

A través de la promoción y difusión de museos, galerías de arte, bienales, investigaciones académicas, etc., el arte contemporáneo se ha convertido en un tema importante de finales del siglo XX.“Arte contemporáneo” fue por un tiempo un término de moda, pero también un término lleno de incertidumbre y desafíos. Esta investigación aborda el arte contemporáneo a través del tiempo, el espacio y la originalidad, explorando la realidad del aburrimiento provocado por la falta de novedad en el arte contemporáneo. Uno de los mayores desafíos del arte contemporáneo es su temporalidad. ¿Cuál es el periodo de tiempo exacto en que se desarrolló el arte contemporáneo? Y en cuanto al espacio, las exposiciones internacionales del arte contemporáneo están frecuentemente dominadas por el arte occidental. ¿Cómo es posible equilibrar el arte contemporáneo de diferentes territorios sin ningún prejuicio? Por otro lado, al seguir el arte contemporáneo el desarrollo del lenguaje artístico del arte de vanguardia, su originalidad y novedad han sido ampliamente cuestionados. Su característica de repetición provoca la reducción de la novedad, y finalmente lleva al aburrimiento a sus espectadores. Pero, ¿es este realmente el destino del arte contemporáneo? Estructuralistas y deconstruccionistas exploran la relación entre el arte contemporáneo y el arte de vanguardia desde diferentes perspectivas, desmantelando el poder y la originalidad del arte de vanguardia. Sin embargo, ¿este tipo de análisis es realmente una forma fiable y significativa de interpretar el arte contemporáneo? ¿O es llevar el arte contemporáneo a la nihilidad y el aburrimiento? Todos estos son los temas que exploramos en esta investigación.
Ellas nos llevaron al espacio
Authors: Lorenzo-González Mª de las Nieves , Calvo-Iglesias Encina , Ávarez-Fernández Inés 
Published: March 2022

En este artículo, presentamos las biografías de algunas de las mujeres que han contribuido a la exploración espacial. Un trabajo que ha permanecido oculto durante mucho tiempo. Afortunadamente, este año 2021 "La mujer en el espacio" ha sido el lema de la Semana Mundial del Espacio, con el propósito de visibilizar los logros y contribuciones de las mujeres al sector espacial y las ciencias. En la misma línea, este artículo pretende por un lado recuperar a las pioneras y por otro fomentar el interés de nuestras jóvenes por las ciencias, ofreciéndoles espejos en los que mirarse.
Validation and reliability of the Munich Shoulder Questionnaire for Turkish patients with shoulder dysfunction
Authors: Kocamaz Deniz , Ekici Gamze , Karabulut Erdem 
Published: March 2022

IntroductionShoulder dysfunction is one of the most important upper extremity problems that limit the quality of life of individuals. Munich Shoulder Questionnaire (MSQ) is a self-assessment tool that allows an easy follow-up and evaluation for clinicians. The aim of this study was to describe the process applied to translate MSQ into Turkish and to test its validity and reliability.MethodsThe questionnaire involves socio-demographic data, as well as objective and subjective items for shoulder dysfunction. The study investigated 180 patients with shoulder dysfunction. Cronbach’s alpha was used to assess internal consistency. Test-retest reliability was evaluated by the intra-class correlation coefficient. Pearson’s correlation coefficient served to examine the convergent validity. The SPSS 23.0 software was used for the statistical analysis.ResultsThe patients’ average age equalled 44.3 ± 11.6 years. In most cases (76.7%), the diagnosis was shoulder impingement syndrome. The Cronbach’s alpha coefficients of the MSQ objective and subjective sections were 0.73 and 0.96, respectively. The MSQ total score was positively correlated with the Disabilities of the Arm, Shoulder and Hand questionnaire total score (<i>r</i> = 0.70; <i>p</i> < 0.01) and the Shoulder Pain and Disability Index total score (<i>r</i> = 0.65; <i>p</i> < 0.01).ConclusionsThe Turkish version of MSQ is a valid, reliable, and responsive instrument for evaluating shoulder dysfunctions. In addition, MSQ-Turkish is satisfactory for evaluating shoulder dysfunctions and its use is recommended to follow up conservative, manipulative, and surgical treatments.
Circumferential pressure treatment reduces post-stroke spasticity: a pilot randomized controlled trial
Authors: Bacca Odair , Patiño-Segura María Solange , Herrera Esperanza 
Published: March 2022

IntroductionCircumferential pressure is used to promote the inhibition of the spastic muscle. The purpose of this study was to evaluate the immediate effect of circumferential pressure applied by Johnstone pressure splint on the tonus level, reflex excitability, and electromyographic activity of plantar flexor and dorsiflexor muscles in post-stroke patients.MethodsAn experimental single-blinded study with random allocation of patients to a control group (conventional inhibition techniques) or experimental group (conventional inhibition techniques along with circumferential pressure) was performed. All patients received one 25-minute therapeutic session. The muscle tonus according to the Modified Ashworth Scale, soleus H-reflex, and electromyographic signals during the sit-to-stand movement of plantar flexor-dorsiflexor muscles were evaluated before and after treatment.ResultsOverall, 30 stroke survivors (20 men, 10 women; age: 60.3 ± 5.7 years; evolution time: 27.8 ± 14.7 months) were studied. The muscle tone decreased in both groups, but the experimental group exhibited a greater reduction. The experimental group presented a significant increase in the H-wave duration and maximal H/maximal M wave ratio of the H-reflex as compared with the control group. No significant difference was observed in muscular electrical activity.ConclusionsOne session of combined therapy contributes to a reduction in the tone of plantar flexor muscles and the reflex activity, without altering the muscle activity.
A ARTE NA EDUCAÇÃO INFANTIL
Authors: Manfrin Benedita Maia de Amorim , Santos Dulcineia de Moraes , Delgado Laura Patrícia Amorim Leite , Oliveira Lucilene Cruz de Souza , Ribeiro Marenil Alessandra de Siqueira , Sousa Márcia do Socorro Dias , Avelar Rosineia Pereira Barcelos 
Published: March 2022

Este artigo pretende identificar como as artes podem ser importantes para o desenvolvimento das crianças, no contexto da formação de indivíduos que possam contribuir positivamente para a sociedade como um todo, um modelo totalmente contrário ao modelo que a escola toma como o objetivo básico de formar pessoas aptas a participar do mercado de trabalho. O caso é que nesse modelo as expressões artísticas e culturais de uma sociedade são fundamentais, pois não são consideradas importantes para a formação da criança e o resultado disso é apenas o acúmulo de conhecimento, não tem efeito mental ou emocional. Para facilitar a conteúdotização do conteúdo apresentado neste artigo, ele foi dividido em cinco temas principais, na forma de apresentar um panorama completo da arte-educação no Brasil.
Percepciones de personas económicamente activas obligadas a realizar trabajo remoto durante la pandemia de COVID-19 por tener una comorbilidad: estudio cualitativo
Authors: Granero Mariano , Viti María , Colombo Malena , Mozeluk Natalia , Terrasa Sergio 
Published: March 2022

Introducción: la probabilidad de presentar una forma grave de COVID-19 es mayor en personas con algunas condiciones preexistentes. En la Argentina, las personas con alguna de estas comorbilidades realizaron un trabajo remoto y diferenciado respecto de sus compañeros. Esta estrategia se denomina shielding y tiene resultados heterogéneos, ya que –si bien evita las infecciones– puede tener algún impacto en las vivencias y salud de las personas.
Métodos: investigación exploratoria a través de un diseño cualitativo basado en entrevistas
semiestructuradas.
Resultados: se realizaron 21 entrevistas. Se organizaron los conceptos en ejes temáticos de análisis. Como principales hallazgos se identificó que la salud general de las personas empeoró durante la pandemia a pesar de realizar trabajo diferenciado, y que durante el período explorado surgieron múltiples emergentes que incluyeron hábitos no saludables y estrategias positivas de afrontamiento. Respecto de lo laboral predominaron los sentimientos negativos.
Conclusión: la implementación de shielding resulta insuficiente como única medida para la preservación de la salud de las personas con mayor riesgo de desarrollar formas graves de COVID-19.