bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis of <i>N</i>-phenethyl-<i>p</i>-methoxycinnamamide and <i>N</i>-morpholinyl-<i>p</i>-methoxycinnamamide, <i>In Vitro</i> and <i>In Silico</i> Study as α-Glucosidase Inhibitor
Authors: Rasyid Herlina , Firdaus Firdaus , Firdausiah Syadza , Soekamto Nunuk Hariani , Seniwati Seniwati , Mardiyanti Riska , Reynaldi Reynaldi , Rahayu Andi Eka Sri , Saputri Wahyu Dita 
Published: December 2022

Aromatic ginger (Kaempferia galanga L.) is one of the natural sources containing ethyl-p-methoxycinnamate, which is known to have beneficial activity, especially as an α-glucosidase inhibitor. This study aims to convert ethyl-p-methoxycinnamate into amide form as N-phenethyl-p-methoxycinnamamide (4a) and N-morpholinyl-p-methoxycinnamamide (4b) through some synthetic ways then tested their activity as an α-glucosidase inhibitor. The FTIR spectra of 4a present a short single peak at 3269.34 cm−1 that belongs to the N-H group, while spectra of 4b show no absorption band between 3200–3400 cm−1 due to its tertiary amide structure. Spectroscopy analysis through 1H- and 13C-NMR exhibits the successful synthesis of both compounds. Bioactivity test results show that compound 4b has better activity than 4a. In molecular dynamics simulation, the binding energy of compounds 4a and 4b reveal that both compounds have a similar binding energy of about -98980.8 and -97696.7 kJ mol−1, respectively.
Yuderkys Espinosa. Una lectura cruzada
Authors:   CIEG-UNAM, López González de Orduña Helena , Lima Nin Alice 
Published: December 2022

En este texto, las autoras proponen una reacción colaborativa al artículo «Hacer geneaología de la experiencia: el método hacia una crítica a la colonialidad de la razón feminista desde la experiencia histórica en América Latina» de Yuderkys Espinosa, publicado en 2019 en la revista Direito e praxis que edita trimestralmente la Universidade do Estado de Rio de Janeiro. Sin renunciar a la reflexión sobre varios aspectos importantes de las teorías y acciones feministas desde Latinoamérica, han armado esta propuesta a partir de una poética experimental situada que pone en crisis la división tajante entre personal y colectivo, privado y público, sin resolverla. Esto conduce a los siguientes cuestionamientos: ¿cómo se activa un feminismo descolonial? ¿Qué hacemos con las teorías y las prácticas feministas? ¿Qué experiencias han suprimido, de acuerdo con qué intereses y estrategias, los feminismos blancos? ¿Qué emociones activan las luchas feministas desde Latinoamérica? ¿En qué sentido nuestra escritura es situada y desapropiada? El deseo de cambiarlo todo, como dice Verónica Gago, ¿es solo una aspiración feminista ? Y, en todo caso, ¿queremos seguir llamándonos feministas?
High levels of dietary digestible protein transiently promote beneficial bacteria in adult dog feces
Authors: Cosío-Carpintero Karina Elizabeth , Gutiérrez Olvera Carlos , Márquez-Mota Claudia Cecilia , Ortega-Cerrilla María Esther , Sánchez González María Guadalupe , Gutiérrez Lilia 
Published: December 2022

Nowadays, many commercial dog diets select the ingredients not only to meet the needs of the individual and maintain a balance between nutrition/microbiome/health; fiber and protein quality is known to be one of the most important factors in this balance. Diets high in low digestible protein tend to favor microorganisms that when fermenting amino acids generate substances that induce inflammation, while high digestible protein and fermentable fibers have been related to beneficial bacteria. The study's objective was to identify changes in the relative abundance of specific microorganisms (Clostridium perfringens, Enterococcus faecium, Lactobacillus salivarius, Bacteroides fragilis and Fusobacterium varium) by PCR (polymerase chain reaction), associated with two diets of different quality and digestibility. Twenty adult dogs were used, divided into two groups, the first one fed with a high digestibility diet (HD) (n = 10), the second one with a low digestibility diet (LD) (n = 10). After 3 days of adaptation to the diet, fecal samples were taken at days 15 and 30. The results showed that the high-quality diet promotes a transient increase (15 days) in the relative abundance of F. varium and E. faecium, as well as a persistent increase in that of L. salivarius and B. fragilis until day 30. Apparently, however, healthy adult dogs eventually balance their fecal microbiota, regardless of the dietary protein level and digestibility. Therefore, it is difficult to identify clear patterns of the ideal dietary profile in this species.
Pengembangan E-LKPD Berbasis Inkuiri Terbimbing pada Materi Larutan Penyangga untuk Siswa Kelas XI SMA/ MA
Authors: Tampubolon Retta Austina , Kurniawati Desy , Aini Syamsi , Effendi Effendi 
Published: December 2022

ABSTRACTThis study aims to generate and measure the value of the validity and practicality of the E-LKPD buffer solution. E-LKPD is prepared based on a guided inquiry model. The type of research used is Research and Development using the plomp development model. The research instrument was a content and construct validity sheet as well as a practicality questionnaire. The E-LKPD was validated by 2 chemistry lecturers at Padang State University and 1 chemistry teacher, as well as a practicality test (field test) through 15 students of class XI SMAN 4 Padang. The results of the study found that the guided inquiry-based worksheets had a high level of category validity (V=0.91) and the practicality level of students with a very practical category on the score (NP=90%). This research is recommended for further research in terms of testing the effectiveness of the products that have been developed.Keywords: Guided Inquiry, E-LKPD, Buffer Solution, Plomp ABSTRAKPenelitian ini bertujuan untuk menghasilkan serta mengukur nilai validitas dan praktikalitasE-LKPD larutan penyangga. E-LKPD disusun berdasarkan model inkuiri terbimbing. Jenis penelitian yang digunakan ialah Reseacrh and Development memakai model pengembangan plomp. Instrumen penelitian berupa lembar validitas konten dan konstruk serta angket praktikalitas. E-LKPD divalidasi oleh 2 orang dosen kimia Universitas Negeri Padang dan 1 orang guru kimia, serta uji kepraktisan (uji lapangan) melalui 15 orang siswa kelas XI SMAN 4 Padang. Hasil penelitian menemukan bahwa LKPD berbasis inkuiri terbimbing memiliki tingkat validitas kategori tinggi (V=0,91) dan tingkat kepraktisan siswa dengan kategori sangat praktis pada nilai (NP=90%). Penelitian ini direkomendasikan untuk penelitian selanjutnya dalam hal uji efektivitas produk yang telah dikembangkan.Kata Kunci: Inkuiri Terbimbing, E-LKPD, Larutan Penyangga, Plomp.
Validity of Interactive Instructional Media Based on CMS-WordPress Website on Hydrocarbon Topic For Senior High School Learning
Authors: Safira Monica Putri , Effendi Effendi 
Published: December 2022

Hydrocarbon is a topic that is considered difficult by students, the lack of concept understanding leads the students into decreasing of interest and motivation, difficulty in learning and misconceptions. Curriculum 2013 demands the students to actively seek, proceed, and developing knowledge in the learning process, as well as skillfully in using media and technology. This study aims to produce interactive learning media based on the CMS-WordPress website on hydrocarbon materials and determine the level of its validity. The type of research used is educational design research using the Plomp model. The research procedure includes the preliminary research stage, the prototyping stage, and the assessment phase. This research is limited to the prototyping stage, namely the validity test to produce prototype III. The media that developed as a whole is categorized as valid, based on the Aiken’s V formula analysis, with a content validity value: 0.86; construct validity value: 0.87; and media validity: 0.94.
Keywords: Hydrocarbon, Web-based Instructional Media, CMS-WordPress, Validity

Hidrokarbon merupakan materi yang dianggap sulit oleh peserta didik, kurangnya pemahaman konsep mengakibatkan peserta didik mengalami penurunan minat dan motivasi belajar, kesulitan mempelajari materi tersebut dan miskonsepsi. Kurikulum 2013 menuntut peserta didik untuk aktif mencari, mengolah dan mengembangkan pengetahuan dalam proses pembelajaran serta terampil menggunakan media dan teknologi. Penelitian ini bertujuan untuk menghasilkan media pembelajaran interaktif berbasis website CMS-WordPress pada materi hidrokarbon dan mengetahui tingkat validitasnya. Jenis penelitian yang digunakan adalah penelitian pengembangan pendidikan menggunakan model Plomp. Prosedur penelitian meliputi tahapan studi pendahuluan, pengembangan atau pembuatan prototipe, dan tahap penilaian. Penelitian ini dibatasi pada tahapan prototyping stage yaitu uji validitas untuk menghasilkan prototipe III. Media yang dikembangkan secara keseluruhan dinyatakan valid berdasarkan analisis formula Aiken’s V, dengan nilai validitas konten sebesar 0,86, validitas konstruk sebesar 0,87, dan validistas media sebesar 0,94.
Kata Kunci: Hidrokarbon, Media Pembelajaran Berbasis Website, CMS-WordPress, Validitas
Multidirectional and Multilevel Models of Enjoyment between Spatial Narration and Multisensory Perceptual Experience
Authors: Chivaran Camelia , Capece Sonia 
Published: December 2022

The contribution reports the research work on models and processes of knowledge transfer for a wide audience combining space perception and experimentation, promoting interactive enjoyment and multisensory participation to the cultural experience for the enhancement of current models.
The acquisition of knowledge from different disciplinary cores – design, archaeology, physics, cognitive sciences, computer science, electronics, art history – allowed tracing the ongoing transformations and obtaining an overview of the current models of fruition both nationally and internationally. The challenge will be to give further emphasis to the improvement of current models and to guide the future design of interactive fruition by bringing together the various aspects analysed in order to return meaningful and customized narrations based on the users’ needs, through perceptual, immersive and multisensory experiences in the spatial dimension of the project, thus engaging the user at multiple levels.
Urban sustainability and urbanization: A review of research topics
Authors: Barki Jasmine Pavković , Barić Andrija , Bach Mirjana Pejić 
Published: December 2022

Abstract
Using a systematic literature review and bibliography, this paper aims to map the research field of urban sustainability. The keywords “urban sustainability and urbanization” were used to search the Web of Science database. Following fair and unambiguous criteria, the most significant research in urban sustainability analysis has been chosen. The fundamental goal of this research is to provide a bibliometric analysis of nearly thirty years of urban sustainability research. In total, 787 articles were extracted from the literature database on the Web of Science. The literature was analyzed using VOSviewer, a scientific mapping software program. Incorporating multiple network analysis approaches such as keyword co-occurrence, co-citation, and bibliographic coupling, VOSviewer is used to determine prominent topic areas and to identify relevant authors, publications, and journals. The present state of urban sustainability research has been assembled to identify research gaps and propose future research paths.
The European Autumn Migration Pattern of the Blackcap, Sylvia atricapilla – From Faunistic Observations to a Basic Analysis of Orientation Cage Field Data
Authors: Busse Przemysław 
Published: December 2022

Abstract
Presentation of a general pattern of migration is very difficult in the case of small passerines, especially nocturnal migrants, as the few accepted methods are inefficient here. It is difficult to follow migration visually (by visual field observations or moon watching). Classic ringing must be extremely intensive due to low or very low recovery rates, especially in Africa, Eastern Europe and Asia, which additionally rule out any reasonable estimation of the intensity of migration towards different destinations. Radar studies tell us nothing about the migration of individual species. Even the most modern methods, such as geolocation and radio tracking, are of very limited use for population studies. For these reasons, in most cases our knowledge in this area is fragmentary and insufficient for a satisfactory description of migration. In many cases only the breeding areas have been faunistically described in detail, while the winter-quarters and areas where the species is observed during migration are frequently described with less precision. The introduction of an effective method for studying local headings of migrants, using ‘orientation cages’, has made it possible to study the migration patterns of small passerine nocturnal migrants. The presented work is a case study on the migration pattern of the Blackcap, using data from orientation tests collected in autumn as part of the work of SEEN (SE European Bird Migration Network), consisting of 5,392 tests performed at 28 ringing sites in Central/Eastern Europe and the Middle East. The paper continues the discussion of the problem of applying the method to presentation of migration patterns in a geographically wide territory (Busse 2018, 2019, 2020).
The hypothesis put forth by Busse (2019) that the arrival/departure heading axes are generally linear is accurate to within about one 10° sector was confirmed earlier. Here it was confirmed at the level of local patterns for the study sites. In general, the average deviation from the straight line is below 1°. However, there is some geographical variation, and this problem could be discussed when many more results of this kind become available for a few more species. Eight headings/streams of migrants are defined for the Blackcap within the area. Southward and south-eastern streams dominate in most of the study area. However, a very special, nearly longitudinal heading was found in southern Europe and the Middle East, which requires further study. Comparison of the patterns obtained from three different procedures strongly suggests that the general picture of Blackcap migration in Central/Eastern Europe and the Middle East is clear and coherent. Some variation in migration stream parameters (linearity and reversed heading share) suggests that further research in this direction should be conducted using data from other species.
Eros y Thánatos, componentes esenciales en la cuentística de Germán Espinosa
Authors: Vanegas Orfa Kelita 
Published: December 2022

En este ensayo se trazan la relación de la muerte y el erotismo en la cuentística de Germán Espinosa. El sentir erótico que significa la inminencia del final de los tiempos, la idea de Thánatos como eje principal de la diferencia entre el ser humano y su entorno animal, la santidad expresa en la negación y vivificada en la burla de las prohibiciones es un vector principal de la obra del autor colombiano, por eso la voluptuosidad de la cotidianidad del instinto negado establece las dimensiones de los personajes a mitad de camino del perfil-carácter de lo que pertenece al mundo que no merece relato y la gran dimensión del esperpento interior que justifica los desencadenantes de la ficción, esperpento interior relatado cual sujeto de leyenda: la muerte que seduce por la piel negada, carne de imaginación que al exponerse será el brillo de la hoz insalvable que entra en acción. Rodar de cabezas y finales de historias que no significan condena, sino quizá la completitud de la angustia tocada por los tintes de carnaval que le corresponden a la literatura
The efficacy of topical adipose mesenchymal stem cell-conditioned medium versus framycetin gauze dressing in chronic plantar ulcer of leprosy: A randomized controlled trial
Authors: Alinda Medhi Denisa , Christopher Paulus Mario , Listiawan Muhammad Yulianto , Endaryanto Anang , Suroto Heri , Rantam Fedik Abdul , Hendradi Esti , Notobroto Hari Basuki , Prakoeswa Cita Rosita Sigit 
Published: December 2022

Background
Wound healing shows a unique interaction of several cells, growth factors and cytokines. The healing of chronic plantar ulcer of leprosy is influenced by various factors, one of which is the concentration of growth factors and cytokines related to the pathogenesis of impaired wound healing. Growth factors and cytokines can be found in the secretome of adipose mesenchymal stem cells.

Aim
To compare the effectiveness of topical adipose mesenchymal stem cell-conditioned medium and framycetin gauze dressing only on the healing of chronic plantar ulcer of leprosy.

Methods
In this randomised controlled trial, 32 patients with chronic plantar ulcer of leprosy were recruited. After detailed clinical and initial debridement, patients were randomised to two groups to receive either topical adipose mesenchymal stem cell-conditioned medium (n = 16) or framycetin gauze dressing only (n = 16) applied every three days for up to eight weeks, following which the ulcer size, adverse reactions and complications if any were monitored weekly.

Results
Healing percentage increased each week in all groups. Statistical differences between groups (P < 0.05) were observed from week 2 onwards for ulcer mean size reduction and from week 3 onwards for ulcer mean depth reduction. There were no adverse reactions or complications.

Limitations
Off-loading on subjects were not performed.

Conclusion
Adipose mesenchymal stem cell-conditioned medium is a potential therapeutic agent in the management of chronic plantar ulcer of leprosy.
Risk factors of deterioration in patients of head injury with non-operative management on first neurosurgical consultation
Authors: Churiwala Jayati , Garale Mahadeo Namdeo , Kawale Juhi , Dandpat Saswat Kumar , Mahore Amit 
Published: December 2022

Objectives:
In most of the emergency trauma intensive care units (ICUs) of India, neurosurgical opinion is sought for patients presenting with head trauma after earliest possible resuscitation to determine the further line of management. This study aimed to identify common risk factors, leading to neurological deterioration in conservatively managed patients of traumatic brain injury (TBI).

Materials and Methods:
This retrospective study analyzed patients admitted with acute TBI and traumatic intracranial hematoma under emergency trauma care ICU who did not require neurosurgical operation within 48 h of trauma. The recorded data were analyzed to determine the predictors of neurological deterioration using univariate and binary logistic regression analysis in SPSS-16 software.

Results:
Medical records of consecutive 275 patients of acute TBI presenting to the emergency department were studied. One hundred and ninety-three patients were afflicted with mild TBI (70.18%), 49 patients had moderate TBI (17.81%), and 33 had severe TBI (12%). In the outcome, 74.54% of patients were discharged, and operative decision was made on 6.18% of patients and 19.27% died. Severe TBI is the independent predictor of neurological deterioration during their stay in ICU. Progressive hemorrhagic injury (PHI) showed neurological deterioration in 86.5% of patients. Systemic inflammatory response syndrome (SIRS) was present in 93.5% of patients who had deteriorated neurologically. Dyselectrolytemia was the biochemical derangements seen in 24.36% of cases.

Conclusion:
This study revealed severe TBI, PHI, and SIRS to be strong and independent risk factors of neurological deterioration.
Theoretical and educational approaches and standards of emergency management in the USA, Great Britain, Australia and the UAE
Authors: Кузина О.А. , Романова Т.А. , Чунова В.Л. 
Published: December 2022

В данной работе рассматривается применение различных аспектов готовности к чрезвычайным ситуациям в таких странах, как Соединенные Штаты Америки (США), Великобритания (СК) и Австралия – странах, которые послужили базой для создания системы чрезвычайных ситуаций в ОАЭ. Расширенный обзор литературы об элементах готовности к чрезвычайным ситуациям и ограничениях их применения в разных странах формирует как теоретическую, так и практическую основу для выявления проблем в ОАЭ. Предполагается, что таким образом удастся лучше разобраться в вопросах, которые делают проблематичной готовность к чрезвычайным ситуациям в ОАЭ, и выявлены те направления, которые требуют улучшения.
The article is devoted to the study of the possibilities of applying cognitive linguistics technologies in In view of this aim, this paper discusses the application of elements of emergency preparedness in countries such as the United States of America (USA), United Kingdom (UK) and Australia, which are countries that have inspired emergency frameworks in the UAE. An extended literature review of elements of emergency preparedness and the limitation of their application in different countries forms both the theoretical and practical basis for identifying the problems in the UAE. It is expected that by so doing, issues which make emergency preparedness problematic in the UAE will be better understood and the areas which require improvement will be brought to light.
ANALISIS MANAJEMEN KEUANGAN LEMBAGA PAUD: STUDI KASUS DI RA PERWANIDA 01 KECAMATAN SUMBERSARI KABUPATEN JEMBER
Authors: Hamidah Ainun , Aisiyah Laily Nur , Atika Aisyah Nur 
Published: December 2022

Manajemen keuangan sekolah merupakan keahlian suatu lembaga sekolah dalam merancang kegiatan secara terstruktur seperti merencanakan, melaksanakan, melaporkan dan mempertanggungjawabkan aktivitas keuangan pendidikan agar berjalan dengan efektif dan efisien. Tujuan penelitiannya yaitu untuk mengetahui manajemen keuangan dalam lembaga sekolah di RA Perwanida 01 Kecamatan Sumbersari Kabupaten Jember. Penelitian menggunakan jenis penelitian kualitatif deskriptif. Subyek penelitiannya adalah kepala sekolah, bendahara, dan guru kelas. Metode pengambilan data yang digunakan yaitu observasi, wawancara dan dokumentasi. Hasil penelitian bahwa terdapat langkah dalam manajemen keuangan sekolah yaitu dalam perencanaan keuangan sekolah dilakukan setiap awal tahun ajaran baru yang pelaksanaannya melakukan rapat internal untuk melakukan musyawarah bersama yang dihadiri oleh kepala sekolah, bendahara sekolah dan guru kelas, pemilihan kegiatan dalam perencanaan disesuaikan dengan kalender akademik serta mempertimbangkan dana yang akan digunakan setelah kesepakatan diambil maka kepala sekolah akan memberitahukaan kepada wali murid dan menyusun RAPBS. Pelaksanaan manajemen keuangan sekolah memiliki dua pembagian yakni penerimaan dana dan pengeluaran dana. Langkah pembukuan manajemen keuangan di sekolah RA Perwanida 01 Jember yakni berupa pembukuan yang sederhana, lengkap dan mudah dipahami sehingga nantinya akan mempermudah dalam laporan dan pertanggungjawaban manajemen keuangan sekolah. Langkah selanjutnya yaitu laporan pertanggungjawaban dilaksanakan dalam dua tahap pelaksanaan yakni setiap bulan serta akhir tahun pelajaran, laporan dan pertanggungjawaban terkait BOP di bawah pengawasan Kementrian Agama sedangkan terkait infak anak di bawah Yayasan Perwanida Jember.