bluuebunny/crossref_metadata_2025_split huggingface dataset:
Difference in PaO2/FiO2 between high-flow nasal cannula and Venturi mask in hypoxemic COVID-19 patients
Authors: Gatto Ilenia , Biagioni Emanuela , Coloretti Irene , Viappiani Serena , Busani Stefano , Girardis Massimo 
Published: May 2022

AbstractThe ratio between arterial blood partial pressure of oxygen and fraction of inspired oxygen (PaO2/FiO2) was largely used for grading and managing the respiratory failure in non-mechanically ventilated COVID-19. In these patients, the assessment of the true FiO2 in the inspired mixture may be difficult with consequent inaccuracies in PaO2/FiO2 assessment. In 30 severe COVID-19 patients, we observed that PaO2/FiO2 values measured immediately before and after the transition from high-flow nasal cannula (HFNC) to one commercially available Venturi mask O2 therapy were similar (bias mean value 0, standard deviation 23 mmHg). In COVID-19 patients recovering from respiratory failure, PaO2/FiO2 is not different whether measured with a commercially available Venturi mask or HFNC.
Applicability of decision tree-based machine learning models in the prediction of core-calibrated shale facies from wireline logs in the late Devonian Duvernay Formation, Alberta, Canada
Authors: Rau Elisabeth G. , James Scott C. , Breen Kathy , Atchley Stacy C. , Thorson Anna M. , Yeates David W. 
Published: May 2022

Well logs provide insight into stratigraphically compartmentalized rock properties and are a cost-effective alternative to core. The identification of reservoir (and nonreservoir) facies in core, and their calibration to well-log response has traditionally relied on expert domain knowledge and is inherently inconsistent. Such analyses are time-consuming, tedious, error prone, and often biased due to a lack of objectivity. Automated lithologic interpretations from wireline logs appear to be a promising solution for identifying and understanding depositional complexity within a reservoir. Using the Duvernay Formation in the Western Canada Sedimentary Basin as a case study, the authors evaluate the applicability of decision tree-based machine learning (ML) methods in the prediction of core-calibrated facies and/or facies association distributions within wireline logs. The authors use three independent decision tree-based ML models to predict (1) facies (FACM), (2) facies associations (FAM), and (3) reservoir rock (RESM) from wireline logs. Model accuracies are 60.3%, 88.1%, and 88.1% for FACM, FAM, and RESM, respectively, but individual class F1 scores range from 0 to 0.92. The authors attribute discrepancies in individual class performance to interval thickness, sample proportion of training data, and distinguishability of the output class. Classes thicker than 3 m and encompassing at least 16% of the training data set have F1 scores greater than 0.60. The authors attribute exceptions to these general cutoffs to the ability to recognize diagnostic sedimentologic features observed in core. Results from this study help in understanding stratigraphic complexity in the absence of core aiding in subsurface characterization of reservoirs.
An image of a woman in a sports advertisement
Authors: Kończak Jarosław 
Published: May 2022

Introduction. In 1987, sport was known in the literature as an area representing a traditional male power, strength and violence. In 2020, women's sport became recognized as the mainstream, which only confirmed similar conclusions made over the past years. One of the challenges in the area of sport over the next years was women’s sport activation and reaching them through sponsorship communication. This has been facilitated, inter alia, by the development of women's sport and its marketing potential.
The study aims to present the image of a woman in marketing communication based on sports motives. The selected aspects subjected to analysis will help to define the role of women in advertising sports communication and verify the declarations of the companies that achieve their goals using this level of communication. Another aim is to investigate whether the belief in the feminization of sports fandom and involvement of women in the fan culture finds confirmation in advertising.
Method. The author has analysed selected TV, cinema and internet advertising campaigns (audio-video format) containing sports accents. Communications of 1,270 films representing 254 brands was analysed. The analysis covered seven different areas: characters, image and product advertising, share of sports disciplines, sports accessories used, the woman’s attitude, an area of the sports involvement, and the values presented.
Results. The analysis allowed to obtain an image of a woman being aware of her strength, who can derive great joy from sport. She believes that this is an important and popular area which has a beneficial effect on health and guarantees a shapely figure and great fun. She is a woman being aware of a number of values that come with sport, as she can see how much she benefits in the spiritual, physical and emotional dimensions. However, she feels her emotions much more often through the way to success and fighting for the position of a leader rather than cheerleading.
Environmentally friendly activities in sports and leisure services as an expression of the corporate social responsibility
Authors: Widawska-Stanisz Agnieszka 
Published: May 2022

Today’s economic reality requires entrepreneurs to introduce many changes, especially those of an organisational nature. The period following COVID-19 pandemic will require organizations to create new values, and a broader view of responsibility, to build mutual trust, and to adapt to the new reality. This paper introduces the principles of Corporate Social Responsibility (CSR), with a focus on ecology as one of the areas of CSR.
It can be seen that the pandemic has accelerated environmental targets in many companies. This is due not only to the regulations aligned with the governmental environmental policy, but to an increasing extent also with changing social expectations. The aim of the article was to demonstrate the applicability of ecological, environment-friendly solutions as an example of CSR in the management of sports and leisure enterprises. CPOR studies show that most young people take responsibility for the state of their environment. The training of the test subjects also plays an important role here (CBOS, Environmental Awareness of Poland, 2020) It is assumed that the introduction of eco-friendly solutions in the operation of sports and leisure businesses is noticed and appreciated only by young participants in physical activity. The survey focuses on specific environmental solutions to create a socially responsible corporate image and how these companies operate in a changing environment.
The results of the studies carried out for this paper are intended to help answer the question of the importance of emphasising environmental aspects and adapting to change by integrating eco-innovation into the CSR strategies of sports and leisure companies, whether these solutions are perceived by the purchasers of sports and leisure services, as they affect their image. and whether they lead to better relations with market participants.
The importance of viral marketing in managing communication in sport
Authors: Kowalski Sławomir 
Published: May 2022

Communication management in sports organizations requires not only the use of formal tools, such as an official website, fan page or official TV channel. Effective communication should also be based on informal methods, in which the main role is played by interactions between the sports organization and its stakeholders.
One such form is viral marketing, which involves sharing files with humorous, social or image content on social networks, messengers, blogs and e-mail. In the case of such forms, due to the wide range and speed of spreading opinions, especially negative ones, about the company, its services or products, it becomes necessary to control the emerging opinions. Management of information with a viral potential allows you to reach stakeholders in an informal way, influencing the building of a positive image, response in crisis situations or creating communities.
The purpose of this paper is to analyze the degree of viral marketing use in sports clubs. The research was conducted in October 2021 on different social media. However, due to the extensive scope of the research, this paper focuses on the social network Facebook. The research is concerned with determining the use of viral marketing potential in information management and identifying the characteristics of this form of influencing stakeholders. Due to the limited volume of the article, the main subject of the study is the Polish clubs of the highest level of competition against the background of examples from abroad.
The main hypothesis of this article assumes that Polish clubs do not fully use the viral potential and communication activities are based on official messages. Communication management is based on peer benchmarking and replication of what others are doing. It is also assumed that departments responsible for communication in sports clubs do not fully use foreign models.
Brain natriuretic peptide measurements using standard biochemical equipment: Comparisons with conventional immunoassays
Authors: Higa Yukie , Nabeshima Yosuke , Kitano Tetsuji , Kataoka Masaharu , Nakazono Akemi , Takeuchi Masaaki 
Published: May 2022

Background
Brain natriuretic peptide (BNP) is an essential cardiac biomarker for diagnosing heart failure and for prognoses in patients with various cardiac diseases. However, measurement requires immunological assays that are not available in every hospital. Recently, a novel BNP kit (Nanopia BNP-A, Sekisui Inc.; BNPn) that uses general-purpose, automated, biochemical analyzers has become commercially available. We assessed how its accuracy and utility compare with those of conventional immunological tests.

Methods and results
We retrospectively collected 1491 conventional BNP measurements (BNPc), which had been clinically indicated for BNP testing and for which residual samples were still stored in the laboratory. We measured BNP using the novel kit and determined the correlation of BNP levels between the two methods. We also assessed the predictive value of both BNP measurements for major cardiac events (MACEs). The analytical performance of both measuring methods was similar. Log-transformed BNP measured by both methods showed strong correlation (r = 0.92); however, log-transformed BNPn was significantly higher than log-transformed BNPc (p<0.001). BNPc of 200 ng/L was used to stratify patients into two groups. According to the regression formula between the two methods, we determined a cut-off value of BNPn as 250 ng/L. During a median of 15 months of follow-up, 43 MACEs developed. Both BNPc and BNPn were associated with MACEs. Kaplan-Meier survival analysis indicated that both BNPc and BNPn cut-off values stratified the high-risk group for prognostication. The diagnostic and prognostic utilities were proven even if the lower cut-off values (BNPc = 100 ng/L, BNPn = 130 ng/L) were employed.

Conclusions
A new BNP measurement using biochemical equipment provides prognostic value similar to that of conventional BNP analysis; thus, it should prove useful in hospitals in which conventional immunological examinations are not available.
De la formación a la profesionalización en la acción cultural: Realidades y perspectivas de futuro en las políticas públicas (Proyecto Xerf@ en Galicia)
Authors: Pose-Porto Héctor , Caride José Antonio 
Published: May 2022

Situamos nuestra contribución en el análisis de distintas circunstancias que concurren en la formación y profesionalización de la acción cultural pública en Galicia. Sin obviar los importantes avances que se han registrado en las últimas décadas en un plano normativo y estratégico, de sus realidades emergen necesidades y demandas que le conceden un especial protagonismo a las decisiones que se adopten en las políticas culturales locales venideras. En el diseño y ejecución de sus programas e iniciativas tienen un papel clave los responsables políticos y técnicos que se vinculan a los distintos servicios, equipamientos, etc. de la gestión cultural municipal, como garantes de los derechos de la ciudadanía a la participación en la creación y disfrute de los bienes culturales de la comunidad. Con este propósito, se exponen algunos de los logros asociados a los planteamientos teórico-conceptuales, metodológicos y empíricos del Proxecto Xerf@ con una visión diagnóstica y prospectiva. Haciendo uso de distintos procedimientos de obtención y tratamiento de la información, los resultados permiten concluir que deben mejorarse la formación inicial y continuada de los profesionales de la acción cultural, así como los distintos procesos orientados a su inserción, desempeño y promoción socio-profesional y laboral.
The Nexus Between Black-Scholes-Merton Option Pricing and Risk: A Case of Ghana Stock Exchange
Authors: Antwi Baafi Joseph 
Published: May 2022

Even though option pricing and its market activities are not new, in Ghana the idea of trading options is yet to be realized. One popular method in pricing options is known as Black-Scholes-Merton option pricing model. Even though option pricing activities are not currently happening on the Ghana Stock Exchange, authors looked at the possibilities and preparedness of the GES to start trading such financial instrument. The main objective of this study therefore was to know how Black-Scholes-Merton model could be used to help in appropriate option value and undertake a risk assessment of stocks on the exchange. This study basically used the black-Scholes formula in calculating the call and put option prices for 28 companies listed GES. The results showed that the price of call option for 18 out of 28 listed stocks showed a value of zero. Again, only seven (7) companies had a value for both call and put options. This means stocks of 21 companies cannot be an underlying asset for trading financial derivatives. Reason for this performance of stock is due to low volatility. The study recommends that policies to increase volatility on the stock market should be put in place in other to make option pricing possible.
Marine macroalgal flora on the Aegean and the Levantine coasts of Turkey
Authors: Taşkın Ergün , Çakır Murat 
Published: May 2022

Abstract
This study contains an updated checklist and new collections of marine algae from the coasts of the Aegean Sea and the Levantine Sea of Turkey. A total of 573 marine algal taxa at specific and infraspecific levels (137 brown algae, 318 red algae, and 118 green algae) are reported, 32 of which are regarded as endangered or threatened macroalgae (four green algae, nine red algae, and 19 brown algae). Of these, 36 taxa (10 brown algae, 17 red algae, nine green algae) are recorded as alien on the Aegean and Levantine coasts. In the present study, the red alga Palisada maris-rubri is reported for the first time from the eastern Mediterranean Sea for Turkey. In Iskenderun Bay, species were sampled from 1 m depth on a volcanic rock in May 2016.
Der Schatten der Liebe
Authors: Pippin Robert 
Published: May 2022

Abstract
There is an unusual link between the two most prominent themes in Proust’s In Search of Time Past: the psychological dimensions of love and the experience of lived temporality. Each experience is shadowed by, and intensified by, even seems to require, absence. The absence of the beloved is the source of jealousy, and that experience is treated as inseparable, and sometimes as indistinguishable, from love itself. And the absence of reliable access to the past, or the vanishing of the past into a realm of fantasy and projection, undermines any confidence in our mutual interpretability. At the extreme, jealousy is depicted as sustaining a love all by itself, something captured in Swann’s famous, puzzling closing statement at the end of the “Swann in Love” section of the first novel: “To think that I have wasted years of my life, that I’ve longed to die, that I have experienced my greatest love, for a woman who didn’t appeal to me, who wasn’t even my type.” The aim of this paper is to understand the dynamic of presence and absence, its role in the link between these two themes, and thereby to understand such a claim as much more than a singular character’s expression of a neurotic obsession.
Maternal serum midkine level in fetal growth restriction: a case-control study
Authors: Oluklu Deniz , Beser Dilek Menekse , Hendem Derya Uyan , Kara Ozgur , Yazihan Nuray , Sahin Dilek 
Published: May 2022

Abstract

Objectives
To compare maternal serum midkine (MK) level in pregnant women with idiopathic fetal growth restriction (FGR) and healthy. In addition, we assessed the value of maternal serum MK level in predicting neonatal intensive care unit (NICU) admission.

Methods
A total of 144 pregnant women were included, 72 with idiopathic FGR and 72 healthy in this study. The control group was matched for the mother’s age, parity, gestational age, and pre-pregnancy body mass index (BMI) with the idiopathic FGR group at the time of recruitment into the study and sample collection.

Results
Serum MK level is higher in the idiopathic FGR than the control group (0.24 ng/mL (0.19–0.32) vs. 0.18 ng/mL (0.14–0.23), p<0.001). In addition, we compared the maternal serum MK level of those with and without NICU admission in the FGR group (0.25 ng/mL (0.19–0.37) vs. 0.21 ng/mL (0.18–0.28), p=0.014). We performed ROC curve analysis to serum MK level predicting NICU admission in the FGR group (AUC: 0.668, %95 CI [0.550, 0.785], p=0.014). A sensitivity of 63% and a specificity of 62% for the serum MK level were achieved with a cut-off value of 0.22 for NICU admission.

Conclusions
To the best of our knowledge, this study is the first to compare maternal serum MK level in pregnant women with idiopathic FGR and healthy. We showed that maternal serum MK level was significantly elevated in pregnant women with FGR than healthy.
Point-of-care haematological monitoring during treatment with clozapine
Authors: Atkins Matthew , McGuire Philip , Balgobin Bhirundra , Williams Sophie , Ceesay Fatou , Desouza Neville , Patel Pravinkumar , Taylor David 
Published: May 2022

Abstract

Objectives
Patients treated with clozapine are required to have regular venous blood samples taken to measure white blood cell (WBC) and neutrophil counts to reduce the risk of agranulocytosis. The need for regular venous blood sampling can deter patients and clinicians from treatment with clozapine. Finger prick sampling offers patients a simpler and less invasive technique that is likely to be more acceptable. We undertook to evaluate a novel point of care testing (POCT) device which measures WBC and neutrophil counts using a small volume of capillary blood from a finger prick sample.

Methods
A total of 215 patients who were being treated with clozapine and were having a venous blood sample taken for haematological monitoring also provided a fingerprick capillary blood sample. The capillary and venous samples were tested using the Sight OLO® POCT analyser, and the venous sample also tested using a standard laboratory method.

Results
For both the WBC and the neutrophil counts, there was a strong correlation between the results from the standard laboratory venous method and the POCT assay (R=0.94 and 0.95, respectively for capillary blood samples, and R=0.98 for both WBC and neutrophil counts for venous blood samples). Compared with the standard laboratory venous blood method, mean biases were −1.0×109/L for WBC and −0.5×109/L for neutrophils for the capillary blood POCT method, and −0.4×109/L for WBC and −0.4×109/L for neutrophils for the venous blood POCT method. Overall, 6 of 215 (2.8%) of patients had levels below clozapine monitoring thresholds (WBC <3.5×109/L and Neutrophils <1.5×109/L) by capillary blood, and 5 (2.3%) by venous blood by POCT. Of these, 2 had sub-threshold counts on the standard laboratory method.

Conclusions
The POCT analyser provided results for both WBC and neutrophil counts that were comparable with those from a standard venous blood laboratory method. Using POCT devices may make haematological monitoring easier in patients being treated with clozapine, and thereby increase the use of clozapine in the treatment of schizophrenia.
Intensity-dependent stimulation of leukocyte telomerase activity by endurance exercise – a pilot study
Authors: Niedrist Tobias , Pailer Sabine , Jahrbacher Renate , Gruber Hans-Jürgen , Herrmann Markus , Renner Wilfried 
Published: May 2022

Abstract

Objectives
Exercise induces telomerase activity and regulates shelterin expression. These effects are believed to preserve telomeres. However, the impact of exercise intensity on telomerase and shelterins has not been studied systematically. This pilot study investigated the kinetics of leukocyte telomerase activity (LTA) and the expression of telomere-related genes in response to exercise at different intensities.

Methods
Seven healthy women completed three exercise sessions at low, moderate and high intensity on a stationary bicycle ergometer. Blood was collected before, 24 and 48 h after each session. LTA, leukocyte telomere length (LTL), expression of telomerase reverse transcriptase (TERT), telomeric repeat binding factor 1 (TERF-1), 2 (TERF-2) and the serum concentration of telomeric repeat binding factor-1 protein (TRF-1) were determined.

Results
LTA increased 24 h after moderate and high intensity exercise and returned to baseline levels after 48 h. TERF-2 expression showed a tendency to decrease 24 h after high-intensity exercise. Other markers (TERT, TERF-1, LTL, TRF-1) were not affected by any intensity.

Conclusions
From the present results it can be concluded that the telomeric effects of exercise are short-lived and depend on the intensity level. Future studies should confirm these results in a larger cohort focusing on the first 24 h post-exercise.
Dengue virus NS1 protein conveys pro‐inflammatory signals by docking onto high‐density lipoproteins
Authors: Benfrid Souheyla , Park Kyu‐Ho , Dellarole Mariano , Voss James E , Tamietti Carole , Pehau‐Arnaudet Gérard , Raynal Bertrand , Brûlé Sébastien , England Patrick , Zhang Xiaokang , Mikhailova Anastassia , Hasan Milena , Ungeheuer Marie‐Noëlle , Petres Stéphane , Biering Scott B , Harris Eva , Sakuntabhai Anavaj , Buchy Philippe , Duong Veasna , Dussart Philippe , Coulibaly Fasséli , Bontems François , Rey Félix A , Flamand Marie 
Published: May 2022

AbstractThe dengue virus nonstructural protein 1 (NS1) is a secreted virulence factor that modulates complement, activates immune cells and alters endothelial barriers. The molecular basis of these events remains incompletely understood. Here we describe a functional high affinity complex formed between NS1 and human high‐density lipoproteins (HDL). Collapse of the soluble NS1 hexamer upon binding to the lipoprotein particle leads to the anchoring of amphipathic NS1 dimeric subunits into the HDL outer layer. The stable complex can be visualized by electron microscopy as a spherical HDL with rod‐shaped NS1 dimers protruding from the surface. We further show that the assembly of NS1‐HDL complexes triggers the production of pro‐inflammatory cytokines in human primary macrophages while NS1 or HDL alone do not. Finally, we detect NS1 in complex with HDL and low‐density lipoprotein (LDL) particles in the plasma of hospitalized dengue patients and observe NS1‐apolipoprotein E‐positive complexes accumulating overtime. The functional reprogramming of endogenous lipoprotein particles by NS1 as a means to exacerbate systemic inflammation during viral infection provides a new paradigm in dengue pathogenesis.