bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does virtual reality enhance the effects of inhibitory control training for loss-of-control eating? A factorial experiment
Authors: Manasse Stephanie M. , Trainor Claire , Payne-Reichert Adam , Abber Sophie R. , Lampe Elizabeth W. , Gillikin Lindsay M. , Juarascio Adrienne S. , Forman Evan M. 
Published: October 2022

Abstract
Inhibitory control, the ability to inhibit one’s automatic responses to desirable stimuli, may be inadequately targeted in interventions for loss-of-control eating. Promising evidence has identified inhibitory control trainings (ICTs) as an avenue to target inhibitory control directly; however, effects of ICTs on real-world behavior are limited. Compared to typical computerized trainings, virtual reality presents several potential advantages that may address key shortcomings of traditional ICTs, i.e. poor approximation to everyday life. The present study utilized a 2x2 factorial design of treatment type (ICT vs sham) by treatment modality (VR vs standard computer) to examine 1) the feasibility and acceptability of six weeks of daily training; 2) the main and interactive effects of treatment type and modality on target engagement and efficacy (i.e., training compliance, change in LOC eating episodes, inhibitory control, and implicit liking of foods). Participants (N = 35) with ≥ 1x/weekly LOC eating were assigned to one of four conditions and completed ICTs daily for six weeks. The treatment was feasible and acceptable, which was supported by high retention and compliance across time and condition. Although completing daily trainings across treatment types and modalities was associated with large decreases in LOC, there were no significant effects of either treatment type or modality, nor a significant interaction effect, on LOC or mechanistic variables. The mechanism driving overall improvements in LOC may be increased goal salience; future research should test whether goal salience interventions may be an effective and highly disseminable treatment option for LOC eating.
An anthropometric study of the morphological facial index of Tibetan youth living in Tibet
Authors: Zhong Hua , Tong Qinghua , Pema Dorjee , Ren Hailong 
Published: October 2022

Abstract

The purpose of this study was to understand gender differences and variations in facial indices among Tibetans and to create and evaluate anthropometric data on facial morphology. The study population consisted of 479 native Tibetans (242 males and 237 females) aged 18–24 years. The median facial width was 134.00 mm for males and 134.40 mm for females; the difference between the genders was not statistically significant. The median facial height was 108.00 mm for males and 115.00 mm for females; the difference between the genders was statistically significant (Z = 5.014, p = 0.000). The median morphological facial index was 80.29 for males and 85.83 for females; the difference between the genders was statistically significant (Z = 3.800, p = 0.000). The proportion of the Tibetan male facial shape was hypereuryprosopic (45.6%) > euryprosopic (31.1%) > mesoprosopic (18.7%) > leptoprosopic (3.3%) > hyperleptoprosopic (1.2%). The proportion of the Tibetan female facial shape was hypereuryprosopic (25.5%) > mesoprosopic (22.6%) > euryprosopic (21.7%) > leptoprosopic (17.4%) > hyperleptoprosopic (12.8%). Facial width was positively correlated with height (male r = 0.306, p = 0.000; female r = 0.144, p = 0.027), weight (r = 0.470, p = 0.000 for males; r = 0.337, p = 0.000 for females), and BMI (r = 0.378, p = 0.000 for males; r = 0.291, p = 0.000 for females). Facial height was positively correlated with height (r = 0.329, p = 0.000 for males; r = 0.137, p = 0.035 for females) and weight (r = 0.391, p = 0.000 for males; r = 0.170, p = 0.009 for females). Facial height was positively correlated with BMI in Tibetan males (r = 0.293, p = 0.000), but no significant correlation was found in Tibetan females. The morphological facial index of Tibetans was positively correlated with age (r = 0.183, p = 0.004 for males; r = 0.171, p = 0.009 for females). The results indicated that Tibetan youth in Tibet have a predominantly hypereuryprosopic facial shape and that facial features are related to age, height, and weight. Some common facial morphology features exist among the Tibet Tibetans, northeastern Indians, and Nepalese in the three different regions of the Sino-Tibetan language family. The data from this study provide basic information for the study of Tibetans in the fields of physical anthropology, forensic medicine, maxillofacial surgery, and plastic surgery.
Evaluation of the risk of SARS-CoV-2 Infection and Hospitalization in Vaccinated and Previously Infected Subjects Based on Real World Data.
Authors: Rossi Maicol Andrea , Cena Tiziana , Binala Jefferson , Alessi Daniela , Scotti Lorenza , Faggiano Fabrizio 
Published: October 2022

Abstract
Background. The objective of our study was to determine the joint protective effect of a previous SARS-CoV-2 infection and vaccination on the risk of a new infection and hospitalization.
Methods. Two case-control studies nested in a cohort of COVID-19 patients cared for by the Local Health Unit (LHU) of Vercelli, Italy, were performed, one to estimate the risk of infection and the second to estimate the risk of hospitalization. Each new infection and hospitalization was matched with up to 4 disease-free subjects who were the same age, sex and index date (i.e., controls). Study subjects were followed up from cohort entry date to disease outcome, end of follow-up or emigration.
Results. Vaccination was associated with a 36% (OR 0.64; 95%CI 0.62-0.66) and 90% (OR 0.10; 95%CI 0.07-0.14) reduction in the risk of infection and hospitalization, respectively. Prior infection was associated with a 65% (OR 0.35; 95%CI 0.30-0.40) and 90% (OR 0.10; 95%CI 0.07-0.14) reduction in the risk of infection and hospitalization, respectively. Vaccinated and recovered subjects showed a 63% (OR 0.37; 95%CI 0.34-0.14) and 98% (OR 0.02; 95%CI 0-0.13) reduction in the risk of infection and hospitalization, respectively.
Conclusions. Vaccination remains an essential public health tool for preventing severe forms of COVID-19. As the Omicron variant has significantly hampered vaccine effectiveness, it will be crucial to ascertain whether the administration of additional booster doses can counteract the ongoing pandemic.
Factors motivating PLWHVA to disclose status to sexual partners: A scoping review
Authors: Molato Boitumelo J , Sibeko Zandile R , Moloko-Phiri Salaminah S , Racoco Kagiso , Thwala Ricardo N , Matsipane Molekodi J 
Published: October 2022

Abstract
Background
Human immunodeficiency virus (HIV) is a public health problem that has destroyed the lives of many people worldwide. As it continues to spread, disclosure of HIV status is fundamental to mitigate the spread of virus, expedite various types of support and improve and well-being of people living with HIV (PLWHVA). Disclosure is a process that takes place without coercion, as PLWHVA should do it voluntarily. Various people are disclosing their HIV statuses to their partners for different reasons. Literature revealed the most of PLWHVA disclosed their HIV statuses to their partners in Sub-Sahara Africa.
Methods
This paper adopted a scoping literature review to achieve the objectives. The following five steps of scoping literature review were the blueprint to guide this paper, namely identifying the research question, identifying the relevant studies, selecting studies, charting data, and finally collating, summarising and reporting the results.
Results
Two themes and six sub-themes emerged from this review. The first theme was facilitation of support and sub-themes were partner support, emotional support, social support, and financial support. The second theme that emerged from this review was health promotion, and sub-themes were protecting loved ones from being infected and enhances medication adherence.
Conclusion
The PLWHVA disclosed their HIV statuses for partners to support them through the entire journey of the illness. The support received from the partners included financial support to enable them to travel to the respective facilities to collect medication. In addition, they needed social and emotional support during difficult times.
Effect of different load during eccentric training with blood flow restriction on muscle size, strength, and motor performance: a randomized controlled trial
Authors: Biral Taíse Mendes , Lemos Leonardo Kesrouani , Cavina Allysiê Priscilla de Souza , Cordeiro Anne Jhuly Cardoso , Junior Eduardo Pizzo , Filho Carlos Alberto Toledo Teixeira , Vendrame Julia Waszczuk , Pastre Carlos Marcelo , Vanderlei Franciele Marques 
Published: October 2022

Abstract
Background
studies on eccentric training with blood flow restriction (BFR) still has gaps, especially in strength and muscle hypertrophy. Therefore, the objective of the study was analyzed and compare the effects of six weeks of eccentric training of knee extensors at different load associated or not with BFR on strength, hypertrophy, and motor performance of knee extensors.
Methods
61 men performed six weeks of quadriceps muscle eccentric training in isokinetic dynamometer were randomized into four groups: high-load eccentric training with BFR (HLET-BFR), low-load eccentric training with BFR (LLET-BFR), high-load eccentric training (HLET) and low-load eccentric training (LLET). The strength, muscle structure and motor performance outcomes were evaluated at baseline, after 3 and 6 weeks of training.
Results
for eccentric peak torque in the first three weeks, HLET was superior to LLET, but similar to LLET-BFR. In the final three weeks, superiority was observed in relation to LLET-BFR; however, there was no difference in relation to HIET-BFR. For the outcomes isometric and concentric peak torque, muscle structure and motor performance, there were no differences between groups.
Conclusion
eccentric training led to strengthening of knee extensors and improved motor performance, but without altering the muscle structure. LLET-BFR promoted gains similar to HLET in the first three weeks of training.
Role of mitochondrial metabolic disorder and immune infiltration in diabetic cardiomyopathy: new insights from bioinformatics analysis
Authors: Peng Cheng , Zhang Yanxiu , Lang Xueyan , Zhang Yao 
Published: October 2022

Abstract
Background
Diabetic cardiomyopathy (DCM) is one of the common cardiovascular complications of diabetes and a leading cause of death in diabetic patients. Mitochondrial metabolism and immune-inflammation are key for DCM pathogenesis, but their crosstalk in DCM remains an open issue. This study explored the separate roles of mitochondrial metabolism and immune microenvironment and their crosstalk in DCM with bioinformatics.
Methods
DCM chip data (GSE4745, GSE5606, and GSE6880) were obtained from NCBI GEO, while mitochondrial gene data were downloaded from MitoCarta3.0 database. Differentially expressed genes (DEGs) were screened by GEO2R and processed for GSEA, GO and KEGG pathway analyses. Mitochondria-related DEGs (MitoDEGs) were obtained. A PPI network was constructed, and the hub MitoDEGs closely linked to DCM or heart failure(HF) were identified with CytoHubba, MCODE and CTD scores. Transcription factors and target miRNAs of the hub MitoDEGs were predicted with Cytoscape and miRWalk database, respectively, and a regulatory network was established. The immune infiltration pattern in DCM was analyzed with ImmuCellAI, while the relationship between MitoDEGs and immune infiltration abundance was investigated using Spearman method. A rat model of DCM was established to validate the expression of hub MitoDEGs and their relationship with cardiac function.
Results
MitoDEGs in DCM were significantly enriched in pathways involved in mitochondrial metabolism, immunoregulation, and collagen synthesis. Nine hub MitoDEGs closely linked to DCM or HF were obtained. Immune analysis revealed significantly increased infiltration of B cells while decreased infiltration of DCs in immune microenvironment of DCM. Spearman analysis demonstrated that the hub MitoDEGs were positively associated with the infiltration of pro-inflammatory immune cells, but negatively associated with the infiltration of anti-inflammatory or regulatory immune cells. In the animal experiment, 4 hub MitoDEGs (Pdk4, Hmgcs2, Decr1, and Ivd) showed an expression trend consistent with bioinformatics analysis result. Additionally, the up-regulation of Pdk4, Hmgcs2, Decr1 and the down-regulation of Ivd were distinctly linked to reduced cardiac function.
Conclusions
This study unraveled the interaction between mitochondrial metabolism and immune microenvironment in DCM, providing new insights into the research on potential pathogenesis of DCM and the exploration of novel targets for medical interventions.
Terminal Digit Preference and Blood Pressure Control in VA Medical Centers
Authors: O'Halloran Meghan , Hughes Ashley , Weaver Frances , Huo Zhiping , Stroupe Kevin , Tarlov Elizabeth , Kramer Holly 
Published: October 2022

Abstract
Background
Few studies have examined terminal digit preference (TDP) and blood pressure (BP) measurement in Veterans Affairs (VA) medical centers.
Methods
This mixed methods study examined TDP for BP measured in Veterans age 18 to 85 years with a hypertension diagnosis during a primary care visit within 8 Midwest VA medical centers from January 1, 2019, through March 1, 2020. TDP for both systolic (SBP) and diastolic blood pressures (DBP) was examined using a goodness of fit test assuming10% frequency for digits 0 through 9. Interviews were conducted with primary care clinicians from 3 VA centers to assess perceptions of BP measurement protocols.
Results
The mean age of the 98,433 Veterans (93% male) was 68.5 years (SD 12.7). Frequency of terminal digits 0 through 9 differed significantly from 10% for both SBP and DBP overall and within each VA center (P < 0.001). The most common terminal digits recorded were 0 and 8 for SBP (14.9% and 14.3%, respectively) and for DBP (17.5% and 14.3%, respectively). Interviews were conducted with 6 LPNs, 1 nurse manager and 6 primary care physicians. Most interviewees reported their clinic BP measurements were performed using semi-automated oscillometric devices but elevated readings were often confirmed by auscultatory methods. Only 5 of the 13 interviewees were aware of a clinic policy for BP measurement for their VA center.
Conclusions
Significant TDP exists for BP measurement in these eight VA centers indicating measurement bias. Future studies should examine strategies for improving BP measurement accuracyto optimize diagnosis and treatment.
Cyclic phosphatidic acid is produced by GDE7 in the ER lumen as a lysophospholipid mediator
Authors: Kitakaze Keisuke , Ali Hanif , Kimoto Raiki , Takenouchi Yasuhiro , Ishimaru Hironobu , Yamashita Atsushi , Ueda Natsuo , Tanaka Tamotsu , Okamoto Yasuo , Tsuboi Kazuhito 
Published: October 2022

Abstract
Cyclic phosphatidic acid (cPA) is a lipid mediator, which regulates adipogenesis and glucose homeostasis by suppressing nuclear peroxisome proliferator-activated receptor γ (PPARγ). Glycerophosphodiesterase 7 (GDE7) is a Ca2+-dependent lysophospholipase D that localizes in the endoplasmic reticulum. Although mouse GDE7 catalyzes cPA production in a cell-free system, it is unknown whether GDE7 generates cPA in living cells. Here, we demonstrate that human GDE7 possesses cPA-producing activity in living cells as well as in a cell-free system. Furthermore, the active site of human GDE7 is directed towards the luminal side of the endoplasmic reticulum. Mutagenesis revealed that amino acid residues F227 and Y238 are important for catalytic activity. GDE7 deficiency derepresses the PPARγ pathway in human mammary MCF-7 cells, suggesting that cPA functions as an intracellular lipid mediator. These findings lead to a better understanding of the biological role of GDE7 and its product, cPA.
A hybrid WSN localization algorithm based on Range-free and TOA positioning method
Authors: Farzadi Maryam , Mohitpour Maryam 
Published: October 2022

Abstract
In most applications of wireless sensor networks, the location of every node within the network is needed for network function. Hence, the plan of node location systems for sensor networks ought to be based on sensor network utilization scenarios so these components make node’s localization in wireless sensor networks a challenging problem. Node’s localization in wireless sensor networks can be partitioned into two common categories of Range-free and Range-based strategies. Distance or Range-based positioning strategies precisely measure distance, while Range-free algorithms utilize communication information between nodes. Range-based procedures generally have two major downsides. First, distance information is easily affected by fading, multipath fading, noise, and environmental changes. Secondly, additional range-finding equipment is usually needed, which increases energy consumption and increases overall cost. One of the advantages of Range-free methods is that they can be implemented at a low cost and its other advantage is its strength because the interconnection information between nodes is not easily affected by environmental conditions, but its major disadvantage is the low accuracy of these methods as compared with Range-based methods. This study can be used to design and implement a WSN localization algorithm to detect abnormalities in a harsh environment such as the Nuclear Power Plant. Given that GPS performs well in outdoor environments and the equipped-GPS sensors would not be working properly in indoor environments such as inside a reactor, the WSN localization algorithm used in such applications must have at least some dependence on GPS technology. We proposed a two-stage localizing algorithm with acceptable accuracy and taking advantage of both Range-free and Range-based methods. In this way, first using the Range-free localization algorithms, the nodes with unknown locations (normal nodes) and with at least three neighboring anchors (which have a known position) will estimate their location. Then, these nodes are considered as anchor nodes for their neighbors. This approach can increase the accuracy of localizing the normal nodes and significantly reduce the number of anchor nodes (equipped-GPS sensors) needed for localization. The results show that the proposed localization algorithm's error as a tool for fault diagnostics is remarkably decreased.
Prediction and validation of melt pool dimensions and geometric distortions of additively manufactured AlSi10Mg
Authors: Ullah Rizwan , Lian Junhe , Akmal Jan , Jiaojiao Wu , Niemi Esko 
Published: October 2022

Abstract
A finite-element (FE) based thermomechanical modeling approach is developed in this study to provide a prediction of the mesoscale melt-pool behavior and part-scale properties for AlSi10Mg alloy. On the mesoscale, the widely adopted Goldak heat source model is used to predict melt pool formed by laser during powder bed fusion process (PBF), which, however, requires the determination of certain parameters as they control temperature distribution and hence melt pool boundaries. An approach based on a systematic parametric study is proposed in the study to determine these parameters, such as absorption coefficient and transient temperature evolution compared with the morphology of melt pool from experiments. Focusing on the part-scale domain, there is increasing demand for predicting geometric distortions and analyzing underlying residual stresses, which are highly influenced by the mesh size and initial temperature (Tinitial) setup. This study aims to propose a strategy for the correlation between the mesh size and the initial temperature to provide correct residual stresses when scaling up the model for efficiency. Results revealed that the predicted melt pool (MP) error produced by optimal Goldak function parameters is between 5–12%. On the part scale, according to the findings, the FE model is less sensitive to mesh size for distortion prediction and layer-lumping can be used to speed up simulation. The effect of large time increments, and layer lumping can be compensated by appropriate Tinitial value for AlSi10Mg.
Protective immunity against Eimeria necatrix infection in Chickens induced by immunization with the recombinant gametocyte antigen EnGAM22
Authors: Liu Dandan , Wang Feiyan , Ye Zhuang , Liu Yue , Wang Lele , Su Shijie , Hou Zhaofeng , Xu Jinjun , Tao Jianping 
Published: October 2022

Abstract
Macrogametocyte stage antigens reportedly provide protective immunity against coccidiosis in poultry. This study was designed to evaluate the ability of a purified recombinant protein from Eimeria necatrix gametocytes (rEnGAM22) to stimulate immunity against experimental infection with sporulated E. necatrix oocysts. The immunogenicity of the recombinant protein was studied in chickens by subcutaneous injection of 25, 50, or 75 µg of the protein with Freund’s adjuvant. Vaccine efficacy was assessed after oral parasite challenge by fecal oocyst output, lesion scores, body weight gain, serum antibodies, and cytokine responses. Chickens vaccinated with 50 µg of rEnGAM22 and challenged with sporulated E. necatrix oocysts showed reduced fecal oocyst shedding and lesion scores compared with other immunized groups and the infected control group, with the exception of the live oocyst group. There was no difference in body weight between the immunized groups and the infected control group. Furthermore, rEnGAM22 also stimulated higher production of anti-rEnGAM22 serum antibodies 7 days after secondary immunization, especially with 50 µg of rEnGAM22. Serum levels of interleukin (IL)-2, IL-4, IL10, and interferon (IFN)-γ also showed the greatest immune response from 50 µg of rEnGAM22, and IL-2 and IL-4 responses were greater than those of IL-10 and IFN-γ. These results indicated that rEnGAM22 protected against E. necatrix infection to some degree and may potentially be used to develop a recombinant subunit vaccine against coccidiosis.
Wire arc additive manufacturing of nanomodified 2024 alloy
Authors: Lopez Maider Arana , Ukar Eneko , Agirretxe Iñaki , Alvarez Pedro 
Published: October 2022

Abstract
Wire arc additive manufacturing (WAAM) has the objective of reducing the fabrication cost and time, as well as the material waste. This technology enables the manufacturing of complex parts near to net shape and as a result, allows greater design freedom. The use of Cold Metal Transfer (CMT) technology facilitates the welding of aluminium alloys susceptible to hot cracking due to the low heat input. One variant of this process, CMT pulsed advance (CMT-PADV), reduces this heat input even more in addition to using alternate polarity, which helps reducing porosity. In this study, nanomodified 2024 alloy is investigated for WAAM applications. Al-Cu aluminium alloys are usually considered non weldable and are highly susceptible to hot cracking. Addition of TiC nanoparticles to the wire enhances nucleation during liquid solid transformation, reducing the size of grains and segregation obtaining as a result a fine equiaxed microstructure. This completely avoids hot cracking of walls and contributed to achieve high isotropic strength after precipitation hardening treatment above 370 MPa yield stress, 450 MPa tensile strength and 4% elongation.