bluuebunny/crossref_metadata_2025_split huggingface dataset:
Presentation of a New Imaging Classification for Giant Dermoid Cyst. Case Report And Literature Review
Authors: Soto Gervith Reyes , Moreno Daniel Alejandro Vega , Rangel Carlos Castillo , Nikolenko Vladmir , Fulcar Mario Alejandro , Segura Neysa Sabrina Vasquez , Chérubin Tshiunza Mpoyi , Aybar Mario Antonio Furcal , Rosario Andreina Rosario , Ramirez Manuel De Jesus Encarnacion 
Published: January 2025

Abstract

Introduction: Intracranial dermoid cysts are rare, benign tumors, making up 0.04–0.6% of brain tumors and originating from ectodermal cells, unlike more complex teratomas from pluripotent germ cells. Dermoid cysts, containing only ectodermal derivatives, differ from epidermoid cysts by lacking dermal appendages. They commonly cause symptoms like seizures and headaches, with specific types associated with their rupture or chronic presence, impacting nearby brain structures.
Material and Method: Our systematic literature review and case series presentation on neurosurgical management of Giant Dermoid Cysts (GDCs) began by identifying 15 full-text articles that met all inclusion criteria were analyzed in detail along with specific cases from our clinical series. These studies and cases provided insights into diagnostic approaches, surgical techniques, and patient outcomes, emphasizing the complexities of complete resection and the use of advanced surgical technologies.
Results: The clinical outcomes of two patients from our case series were also included: a 32-year-old female presented with progressive headaches and occasional dizziness, undergoing subtotal resection with two subsequent surgeries due to recurrence over a 10-year period, and a 45-year-old male experiencing dizziness and seizures, who underwent successful total resection with no recurrence after 10 years.
Conclusions: This study highlights the complexities involved in managing Giant Dermoid Cysts (GDCs) neurosurgical and underscores the critical role of advanced diagnostic and surgical technologies in improving patient outcomes. Importantly, the introduction of the Reyes-Velez classification system offers a structured approach to diagnosing and managing these cysts, providing clinicians with a valuable tool to enhance surgical planning, predict potential complications, and guide therapeutic decisions. This new classification system is instrumental in advancing the standardization and effectiveness of treatment protocols for GDCs.
Accessible data collection methods in clinical trials: Do current best practices for the implementation of electronic patient-reported outcome measures (ePROMs) meet accessibility standards?
Authors: Mowlem Florence Daisy , O'Donohoe Paul 
Published: January 2025

Abstract

Background
Apps and web browsers, whether on smartphones, tablets or laptops, have become the mainstream methods of capturing clinical outcome assessment (COA) data, and patient-reported outcome measures (PROMs) in particular, in clinical trials. There has long been concern around whether implementing traditionally paper-based questionnaires on electronic systems may impact the measurement properties of these carefully validated questionnaires, with migration best practices focusing predominately on this issue. In parallel, app and web-design best practices outside of clinical research have focused on the accessibility and usability of these electronic systems for the widest range of users.
Methods
This article evaluates how existing Web Content Accessibility Guidelines (WCAG 2.2) compare to electronic PROM (ePROM) design best practices, identifying where there is alignment or tension, where further evidence is needed to ensure both accessibility and the maintenance of the questionnaire measurement properties, and what accessibility practices can be incorporated into ePROM design best practices today.
Results
Many of the accessibility criteria can be applied to electronic clinical outcome assessment (eCOA) systems now without concern for the integrity of the measure, given their focus is on the software being programmed and built to support content being implemented in a way that enhances overall accessibility and its usability with assistive technologies. The main tensions identified between the accessibility success criteria and ePROM best practices concerned increasing content size and device orientation.
Conclusions
Many accessibility best practices can be adopted in ePROM implementations today, and we must strive to achieve a point where accessibility best practices are (e)PROM best practices to ensure electronic data capture is accessible and usable, leading to more representative trials that are lower burden for patients.
Association between the Weight-Adjusted Waist Index and Low Back Pain: A Nationally Representative Cross-Sectional Study Using Data from the NHANES 1999–2004
Authors: Yu Weijie , Zhang Yihan , He Chenyu , Yue Xianlong , Jia Mengxian , Chen Minghang , Teng Honglin , Zhou Yang 
Published: January 2025

Abstract

Background: Evidence indicates that the correlation between obesity and low back pain (LBP) is likely multifactorial. To date, no studies have examined the correlation between the weight-adjusted waist index (WWI) and LBP. This study aimed to investigate the clinical and demographic profiles of individuals with and without LBP and examine the potential role of WWI as a risk factor and predictor of LBP.
Methods: In this cross-sectional study, we examined a cohort of adult participants who provided comprehensive data on WWI and LBPfrom the 1999–2004 National Health and Nutrition Examination Survey. WWI was calculated by dividing waist circumference by the square root of body weight. We explored the association between WWI and LBPusing binary logistic regression modeling and propensity score matching.
Results: The study included 8,041 participants aged over 20 years, of whom 3,134 had a history of LBP. A significant positive correlation was found between WWI and LBP in participants aged over 65 years, indicating that WWI is a strong predictor of LBP in old age groups. In contrast, the relationship between WWI and LBP was less consistent in participants aged 20–64 years, suggesting that other factors may have a more significant influence in other age groups.
Conclusion:
The findings of this study underscore the significance of the WWI as a potential predictor of LBP, particularly in older adults. The robust association observed between higher WWI and the increased prevalence of LBP in individuals highlights the importance of central adiposity as a clinical marker.
Effect of compatibilizer and coupling agent on Properties of Ethylene Vinyl Acetate/ Natural Rubber/ Potash Feldspar (EVA/NR/PF) Composites
Authors: Ho Shuh Huey , Chan Ming Yeng , Koay Seong Chun 
Published: January 2025

Abstract

In this paper, the effect of coupling agent (glycolic acid- maleic anhydride treated potash feldspar) and compatibilizer (ethylene vinyl acetate- grafted- benzyl urea) on the tensile test, morphology, FTIR, and thermal properties of EVA/NR composites had been investigated. EVA/NR/PF, EVA/NR/PFGAMA and EVA/NR/PF/EVA-g-BU composites were prepared using brabender plasticoder at temperature of 160 ºC and rotor speed of 50 rpm. EVA/NR/PF, EVA/NR/PFGAMA and EVA/NR/PF/EVA-g-BU composites showed lower tensile strength and elongation at break but higher modulus at 100% elongation (M100) at higher PF loading. However, higher tensile strength, modulus at 100% elongation, thermal stability but lower elongation at break, and crystallinity were illustrated for EVA/NR/PFGAMA and EVA/NR/PF/EVA-g-BU composites. At higher PF loading, EVA/NR/PF composites exhibited smooth surface and the presence of voids and agglomerations. However, EVA/NR/PFGAMA and EVA/NR/PF/EVA-g-BU composites displayed rougher surfaces in comparison to EVA/NR/PF composite. The presence of N-H group from the benzyl urea in EVA/NR/EVA-g-BU composites was found at the absorption of 3434.2 and 3330 cm-1.
Comunicação de Más Notícias: o Psicólogo como Mediador entre o Médico e a Família do paciente na Unidade de Tratamento Intensivo (UTI)
Authors: Rocha Muniz Thaira Stefani , Novaes Vieira Vanessa , Rosa Assis de Oliveira Thiago 
Published: January 2025

O presente artigo científico traz o papel do psicólogo hospitalar na mediação de más notícias entre a tríade médico-paciente-família, dando ênfase principalmente aos familiares dos pacientes internados em uma unidade de tratamento intensivo (UTI). Objetivou-se identificar quais são os processos da comunicação encontrados no contexto hospitalar; conceituar os protocolos de comunicação de más notícias desenvolvidos para auxiliar os profissionais de saúde a tornar a comunicação mais efetiva e menos prejudicial ao paciente e seus familiares e apresentar o papel do psicólogo hospitalar como facilitador neste processo de comunicação de más notícias. A metodologia utilizada foi uma pesquisa descritiva, com abordagem qualitativa em formato de pesquisa bibliográfica, realizada a partir de uma síntese entre diversos autores, dentre livros e artigos científicos, que abordam a importância da comunicação efetiva do ambiente hospitalar. Diante da pouca literatura encontrada sobre o papel do psicológo hospitalar na comunicação de más notícias em UTI fez-se necessário à realização desse artigo a fim de trazer mais considerações sobre esse tema. Concluiu-se que o psicólogo hospitalar tem grande importância dentro do contexto de más notícias, visto que esse é o profissional capacitado para uma escuta diferenciada e uma observação minuciosa, na qual é possível a ele perceber quando a comunicação não está acontecendo de forma efetiva.
One-pot, Four-component Synthesis, Molecular Docking and Pharmacokinetic
Studies of Tetra-substituted Imidazole Derivatives as Potential Mushroom
Tyrosinase Inhibitors
Authors: Naseem Muhammad , Rafique Hummera , Roshan Sadia , Ashraf Zaman , Perveen Fouzia , Tayyab Muhammad 
Published: January 2025

Introduction:
An efficient and four-component one-pot facile synthesis of tetra-substituted imidazole
is achieved by cyclo-condensation reaction of benzil with subsequent successive substitution of aromatic
aldehydes, ester substituted amine and ammonium acetate via refluxing the mixture for almost two hours at
140°C.

Method:
The ending point of the understudy reaction was examined by TLC after regular intervals. Synthesized
1,2,4-tetrasubstituted imidazoles were characterized by physical data and the structural features were
analyzed using spectroscopic techniques such as FTIR, NMR and elemental analysis.

Results:
The inhibition potential of fabricated compounds was evaluated against the mushroom based Tyrosinase
(polyphenol oxidase) enzyme. Tetra-substituted imidazole derivatives demonstrated significant potent
tyrosinase inhibition activities.

Conclusion:
Pharmacokinetic mechanism and molecular docking studies were also carried out
In Web We Trust: The Promised Cannabidiol Effects on Obesity as a
Matter of Language and Marketing on Webpages
Authors: Roberti Roberta , Comacchio Carla , Colizzi Marco , Mallio Carlo Augusto , Russo Emilio , Di Gennaro Gianfranco 
Published: January 2025

Background:
Today more and more people search the web for health-related information,
risking to come across misinformation and biased content that may affect their treatment decisions.
Cannabidiol (CBD) is among the products for which beneficial effects have been claimed, often at
the expense of the risks; further keeping in mind unreliable information reported on products themselves.

Objective:
This study evaluated the quality of information retrieved by Google on the potential effects
of CBD on weight management, also comparing Italian and English contents, hypothesizing
generally low quality and language-driven differences in offered information.

Methods:
Queries regarding cannabidiol and obesity-related terms were entered into Google, ranking
the first 50 webpages from both merged Italian and English results for analysis.

Results:
Of the outputs, 37 Italian and 27 English websites addressed the topic and were not related
to medical literature. As expected, a substantial proportion of information was of low quality, with
English sites performing better (29.6%) than Italian ones (54%, p = 0.052) in terms of “JAMA
benchmarks” for trustworthiness of information. Also, while most English sites were “Health portals”
(40.7%) with neutral stance toward CBD (74.1%), Italian ones were predominantly “commercial”
(78.4%, p = 0.001) and promoting CBD use (89.2%, p < 0.001).

Conclusion:
Findings suggest the need for better online information, especially in non-Englishspeaking
countries, as scarce and unequal information can lead people to make poor health choices,
with potentially harmful consequences.
Development of a Prediction Model and Risk Score for Self-Assessment and High-Risk Population Identification in Liver Cancer Screening: Prospective Cohort Study
Authors: Li Xue , Wang Youqing , Li Huizhang , Wang Le , Zhu Juan , Yang Chen , Du Lingbin 
Published: January 2025

Abstract

Background
Liver cancer continues to pose a significant burden in China. To enhance the efficiency of screening, it is crucial to implement population stratification for liver cancer surveillance.

Objective
This study aimed to develop a simple prediction model and risk score for liver cancer screening in the general population, with the goal of improving early detection and survival.

Methods
This population-based cohort study focused on residents aged 40 to 74 years. Participants were enrolled between 2014 and 2019 and were prospectively followed until June 30, 2021. Data were collected through interviews at enrollment. A Cox proportional hazards regression was used to identify predictors and construct the prediction model. A risk score system was developed based on the weighted factors included in the prediction model.

Results
A total of 153,082 study participants (67,586 males and 85,496 females) with a mean age of 55.86 years were included. During 781,125 person-years of follow-up (length of follow-up: median 6.07, IQR 3.07‐7.09 years), 290 individuals were diagnosed with liver cancer. Key factors identified for the prediction model and risk score system included age (hazard ratio [HR] 1.06, 95% CI 1.04‐1.08), sex (male: HR 3.41, 95% CI 2.44‐4.78), education level (medium: HR 0.84, 95% CI 0.61‐1.15; high: HR 0.37, 95% CI 0.17‐0.78), cirrhosis (HR 11.93, 95% CI 7.46‐19.09), diabetes (HR 1.59, 95% CI 1.08‐2.34), and hepatitis B surface antigen (HBsAg) status (positive: HR 3.84, 95% CI 2.38‐6.19; unknown: HR 1.04, 95% CI 0.73‐1.49). The model exhibited excellent discrimination in both the development and validation sets, with areas under the curve (AUC) of 0.802, 0.812, and 0.791 for predicting liver cancer at the 1-, 3-, and 5-year periods in the development set and 0.751, 0.763, and 0.712 in the validation set, respectively. Sensitivity analyses applied to the subgroups of participants without cirrhosis and with a negative or unknown HBsAg status yielded similar performances, with AUCs ranging from 0.707 to 0.831. Calibration plots indicated an excellent agreement between the observed and predicted probabilities of developing liver cancer over the 1-, 3-, and 5-year periods. Compared to the low-risk group, participants in the high-risk and moderate-risk groups had 11.88-fold (95% CI 8.67‐16.27) and 3.51-fold (95% CI 2.58‐4.76) higher risks of liver cancer, respectively. Decision curve analysis demonstrated that the risk score provided a higher net benefit compared to the current strategy. To aid in risk stratification for individual participants, a user-friendly web-based scoring system was developed.

Conclusions
A straightforward liver cancer prediction model was created by incorporating easily accessible variables. This model enables the identification of asymptomatic individuals who should be prioritized for liver cancer screening.
The Feasibility of Large Language Models in Verbal Comprehension Assessment: Mixed Methods Feasibility Study
Authors: Hadar-Shoval Dorit , Lvovsky Maya , Asraf Kfir , Shimoni Yoav , Elyoseph Zohar 
Published: January 2025

Background
Cognitive assessment is an important component of applied psychology, but limited access and high costs make these evaluations challenging.

Objective
This study aimed to examine the feasibility of using large language models (LLMs) to create personalized artificial intelligence–based verbal comprehension tests (AI-BVCTs) for assessing verbal intelligence, in contrast with traditional assessment methods based on standardized norms.

Methods
We used a within-participants design, comparing scores obtained from AI-BVCTs with those from the Wechsler Adult Intelligence Scale (WAIS-III) verbal comprehension index (VCI). In total, 8 Hebrew-speaking participants completed both the VCI and AI-BVCT, the latter being generated using the LLM Claude.

Results
The concordance correlation coefficient (CCC) demonstrated strong agreement between AI-BVCT and VCI scores (Claude: CCC=.75, 90% CI 0.266-0.933; GPT-4: CCC=.73, 90% CI 0.170-0.935). Pearson correlations further supported these findings, showing strong associations between VCI and AI-BVCT scores (Claude: r=.84, P<.001; GPT-4: r=.77, P=.02). No statistically significant differences were found between AI-BVCT and VCI scores (P>.05).

Conclusions
These findings support the potential of LLMs to assess verbal intelligence. The study attests to the promise of AI-based cognitive tests in increasing the accessibility and affordability of assessment processes, enabling personalized testing. The research also raises ethical concerns regarding privacy and overreliance on AI in clinical work. Further research with larger and more diverse samples is needed to establish the validity and reliability of this approach and develop more accurate scoring procedures.
Pembelajaran Berbasis Proyek Untuk Meningkatkan Kreativitas Dalam Pendidikan Jasmani
Authors: Ni Wayan Suardiati Putri  , I Ketut Budaya Astra  , Ketut Agustini  , I Gde Wawan Sudatha  
Published: January 2025

Saat ini siswa tidak hanya mempunyai pengetahuan saja tetapi juga mempunyai keterampilan dan sikap. Untuk meningkatkan keterampilan dan sikap, siswa perlu diberikan pengalaman nyata dalam bentuk proyek. Tujuan penelitian ini adalah untuk mempelajari literatur tentang peningkatan kreativitas siswa pendidikan jasmani melalui model pembelajaran berbasis proyek. Metode penelitian yang digunakan dalam penelitian ini adalah Systematic Literature Review (SLR) dengan PRISMA (Preferred Reporting Items For Systematic Review And Meta-Analyses) yang bertujuan untuk memastikan bahwa setiap proses yang dilakukan pada saat melakukan review berjalan secara sistematis. Penelusuran literatur dilakukan dengan bantuan aplikasi Publish or Perish. Teknik pengumpulan data yang digunakan meliputi analisis teori dan hasil artikel ilmiah serta publikasi lainnya dengan tujuan untuk mengetahui dampak pembelajaran berbasis proyek. Hasil dari penelitian ini adalah Project Based Learning (PjBL) dapat meningkatkan kreativitas siswa, dan pendidikan jasmani dengan model pembelajaran berbasis proyek membantu siswa menjadi aktif. Model pembelajaran PjBL dapat dijadikan acuan untuk diterapkan pada pembelajaran pendidikan jasmani di sekolah. Model pembelajaran PjBL dapat diterapkan secara sistematis dan efektif di berbagai tingkat satuan pendidikan, mulai dari sekolah dasar hingga perguruan tinggi. Disimpulkan bahwa pentingnya PjBL dalam pendidikan jasmani untuk meningkatkan kreativitas siswa.
Optimalisasi Pembelajaran Penjas pada Ranah Psikomotorik Mata Pelajaran Penjas Materi Bulutangkis
Authors: Ade Yuni Sahruni  , CS Ansar , Syahruddin  , Muh Syaiful Syam  , Andi Baso Husain  , Muhammad Sadzali  
Published: January 2025

Beberapa siswa masih sering melakukan kesalahan dalam teknik dasar seperti servis yang tidak sampai dan smash yang tidak efektif. Hal ini menimbulkan masalah sebab meskipun antusiasme siswa tinggi, dan beberapa siswa mencapai prestasi luar biasa, kemampuan teknik dasar yang tidak merata dapat menghambat perkembangan keterampilan seluruh siswa secara konsisten. Tujuan penilitian yaitu untuk menganalisis tingkatan keberhasilan pembelajaran penjas pada ranah psikomotorik mata pelajaran bulutangkis. Jenis Penelitian ini yaitu deskriptif kuantitatif. Adapun metode pengumpulan data yang digunakan yaitu menggunakan tes dari rubrik penilaian rencana pelaksanaan pembelajaran (RPP). Populasi penilitian adalah siswa kelas X yang berjumlah sebanyak 70 siswa. Instrumen penelitian ini menggunakan penilaian mandiri dengan berdasarkan tingkat keberhasilan psikomotorik servis pendek. Setelah data dikumpulkan kemudian dianalisis menggunakan metode analisis deskriptif kuantitatif. Hasil penelitian tingkat Pembelajaran pada ranah psikomotorik mata pelajaran penjas dengan materi bulutangkis dikategorikan pada tingkat sedang. Hal ini disebabkan oleh penggunaan model pembelajaran yang belum sesuai dengan kapasitas pemahaman dan daya tangkap seluruh siswa. Kurangnya sarana dan prasarana di sekolah juga berdampak negatif terhadap proses pembelajaran. Dari data ini dapat disimpulkan bahwa tingkat penguasaan teknik dasar bulutangkis oleh siswa berada pada level yang cukup baik, namun masih memerlukan peningkatan untuk mencapai kategori yang lebih tinggi. Penelitian ini diharapkan dapat menjadi acuan bagi sekolah dalam mengadopsi pendekatan yang lebih terstruktur sehingga dapat mencapai tujuan pembelajaran psikomotorik dan mengoptimalkan potensi siswa dalam olahraga.