bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improving indoor air quality and occupant health through smart control of windows and portable air purifiers in residential buildings
Authors: Wang Yan , Cooper Elizabeth , Tahmasebi Farhang , Taylor Jonathon , Stamp Samuel , Symonds Phil , Burman Esfandiar , Mumovic Dejan 
Published: May 2022

Indoor exposure to PM2.5 (particulate matter with aerodynamic diameter less than 2.5 μm) has a substantial negative impact on people’s health. However, indoor PM2.5 can be controlled through effective ventilation and filtration. This study aimed to develop a smart control framework that (1) combines a portable home air purifier (HAP) and window control system to reduce indoor PM2.5 concentrations whilst maintaining thermal comfort; (2) evaluates the associated health impacts and additional energy use. The proposed framework was demonstrated through a simulation-based case study of a low-energy apartment. The simulation results showed that joint control of HAP and window openings has great potential to not only maintain thermal comfort but also achieve effective PM2.5 removal which, consequently, can lead to considerable health benefits at a low additional energy cost. Compared to similar previous studies, the strength of the proposed control framework lies in combining window operations and HAPs in the same system and including both thermal comfort and indoor PM2.5 as the control targets. This work also introduces a novel concept of linking a building control system with a health impact assessment, an important and innovative step in the creation of holistic and responsive building controls. Practical application: This study proposes a novel control framework that jointly controls portable home air purifiers (HAPs) and windows to maintain thermal comfort and achieve effective PM2.5 removal. The simulation results suggest that such a hybrid control strategy can result in considerable health benefits at low additional energy costs.
A case report of adolescent respiratory epithelial adenomatoid hamartoma
Authors: Lin Yu-Wen , Lai Kuan-Ju , Shen Kuang-Hsuan 
Published: May 2022

Hamartomas are common in the lung, kidney, liver, spleen, and, but rare, in the sinonasal tract. Respiratory epithelial adenomatoid hamartomas (REAHs) are benign lesions common in men aged 30 to 90 years. Approximately 70% of REAHs in the head and neck region originate from the posterior nasal septum. We present an unusual case of REAH originating from the maxillary sinus and extending to the nasopharynx of an adolescent boy. A 17-year-old boy without any salient medical history presented to our department with nasal obstruction that had persisted for 7 years as well as greenish nasal discharge, hyposmia, and a complaint of fetid smell. Sinoscopy of the osteomeatal complex (OMC) revealed bilateral mucopus and a large right polypoid tumor extending into the nasopharynx. Computed tomography of the paranasal sinuses revealed soft-tissue opacification around the right OMC, frontal sinus, ethmoid sinus, maxillary sinus, and nasopharynx. We performed bilateral endoscopic sinus surgery. REAH and chronic rhinosinusitis with nasal polyps were diagnosed on the basis of a pathology report. No evidence of recurrence was observed by 6 months after surgery, and his hyposmia, nasal obstruction, and purulent nasal discharge were alleviated considerably. Accurate diagnosis based on pathology is essential for determining the optimal treatment, which for REAH is complete surgical excision.
Quality of Life and Disability in Patients with Dhat Syndrome: A Cross-Sectional Study
Authors: Shahi Mohit Kumar , Tripathi Adarsh , Singh Astha , Kar Sujita Kumar , Nischal Anil , Singh Shweta , Dalal Pronob Kumar 
Published: May 2022

Background: Dhat syndrome (DS) is considered a culture-bound syndrome of South East Asia. It is often associated with multiple sexual and psychiatric comorbidities. We aimed to assess the quality of life (QoL) and disability in patients of DS with and without comorbidity. Methods: This cross-sectional study included 117 patients with DS and 117 matched controls. DS was diagnosed based on the International Classification of Diseases, 10 version, Diagnostic Criteria for Research diagnostic criteria. Comorbidities were assessed on MINI 6.0.0, and the patients were divided into two groups (with and without comorbidity). The QoL and disability were estimated and compared between patients with and without comorbidity and their respective control groups consisting of healthy volunteers, using standardized tools. Result: Most of the patients were unmarried males aged 18 to 25 years and from rural backgrounds. Most of the patients (72.64%) had comorbidities (psychiatric/sexual). The QoL of patients with DS was poor compared to healthy individuals. The QoL of patients with comorbidity was worse than that of those without them (P < o.ooo). The disability of patients with DS was more than that of healthy individuals (significant in all domains of the World Health Organization Disability Assessment Schedule [WHODAS]). Conclusion: Patients having DS had poor QoL and higher disability than healthy controls. Patients having psychiatric or sexual comorbidities had less QoL and higher disability compared to healthy controls and those without comorbidities.
IP-10 and complement activation as friend or foe in COVID-19
Authors: Bunprakob Saowalak , Hemachudha Pasin , Ruchisrisarod Chanida , Supharatpariyakorn Thirawat , Hemachudha Thiravat 
Published: May 2022

Introduction The Innate immune system senses danger signals of COVID-19 infection and produce an orchestration of cellular, complement and cytokines cascades. These led to the approach using immunosuppressive agents. It is intriguing whether certain biomarkers can aid the proper administration of such drugs. Methods Plasma specimens of 58 COVID-19 patients with differing severity, from very mild illness (group A), mild (group B), moderate (group C), and severe/critical illness (group D) were assayed for cyto-chemokines and terminal complement complex (SC5b-9) during the course of diseases. None received anti-IL-6 therapy, there was no mortality in this cohort. Results IP-10 and RANTES levels were dominant cytokines. IP-10 levels increased significantly in all groups when compared between pre-nadir and nadir phases (group A, p =0.428; group B =0.034; group C =0.159; group D <0.001) and in groups B and D when compared between nadir and recovery phases ( p <0.001). RANTES levels were elevated in all groups across all phases with no significant differences. SC5b-9 levels increased significantly as compared to healthy controls [pre-nadir- group A versus healthy, p =0.122; group B-D versus healthy, p =0.021); nadir-group A versus healthy, p =0.003; group B-D versus healthy, p <0.001; recovery phase ( p <0.001)] but not between groups A and B-D at pre-nadir ( p=0.606). Conclusion The absence of significant pro-inflammatory responses and early elevation of IP-10 levels and complement activation may be favorable and necessary for viral elimination in COVID-19 patients. Expression of distinct cyto-chemokines during each clinical phase may be useful for guiding proper therapeutic interventions on alleviating thrombo-inflammation responses to COVID-19 infection.
The Body in Crisis: A Health Needs Assessment among Female Survivors of Interpersonal Violence
Authors: Chhetri Shlesma , Gonzalez-Pons Kwynn , Andrews Alita , Carlson Erin , Grace Jessica , Thompson Erika L. , Spence Emily E. 
Published: May 2022

Background When women who experience violence seek social services, they are looking to meet immediate needs: shelter, safety, and support. Seeking assistance as part of a crisis may inadvertently detract attention away from other critical needs. Literature illustrates the emotional and physical effects of violence on women’s bodies, as well as their long-term health. While health may present as an urgent need in cases of serious injury, it is often overlooked in crisis-oriented service delivery systems. This study explored the experience with violence, health status, and holistic healthcare needs among women accessing interpersonal violence services in Texas. Methods A tablet-based survey was conducted at a family justice center, rape crisis center, and emergency shelter among women ( N = 99) in Fort Worth, Texas. Survey questions assessed the participants’ demographic information, health status, health needs, healthcare utilization, barriers to accessing healthcare, and experience with interpersonal violence among participating women. Results Two-thirds of the sample reported suffering injuries from victimization experiences. More than half of the sample (62%) reported they went to the emergency room at least one time in the last 6 months, with 11 women reported staying five or more nights in the hospital in the last 6 months. Participants described urgent (e.g., advised by healthcare provider, too serious for a clinic) and non-urgent (e.g., not having another source of care, closest provider) reasons for using the emergency room. Roughly, half of the sample (50%) reported having at least three chronic conditions. Discussion This study illustrated that women seeking interpersonal violence related (IPV) services have multiple unmet needs and lack adequate access to physical and mental health care. Since the majority of the sample was living in poverty, there are multiple costs and investments in the participants’ health that were forgone for their survival. This study provides data in support of the development of health-related services for IPV survivors.
Grapiprant or carprofen following ovariohysterectomy in the cat: analgesic efficacy, hematological, biochemical and urinalysis evaluation
Authors: Teixeira Luciana G , Vaccarin Charline V , Schimites Paula I , Gasparotto Jean C , Costa Gabriela P , Griesang Julia M , Vargas Daniel , Bortolotto Emanuelle D , Soares Ana BU , Camargo Jéssica F , Andrade Cínthia M , Soares André V , Contesini Emerson A 
Published: May 2022

Objectives This study aimed to compare the analgesic effect between carprofen and grapiprant every 12 or 24 h on postoperative pain in cats undergoing ovariohysterectomy, in addition to the effects on the hematological, biochemical and urinalysis variables. Methods A total of 32 female cats were randomly divided into three groups, according to the treatment administered with the first dose given orally 90 mins before surgery, as follows: CAR (cats received 4 mg/kg carprofen, n = 11); GRA1 (cats received 2 mg/kg grapiprant, n = 10); and GRA2 (cats received 2 mg/kg grapiprant q12h, n = 11). Pain was assessed by UNESP-Botucatu Multidimensional Composite Pain Scale (UNESP) and Glasgow Feline Composite Measure Pain Scale (GLASGOW) for cats preoperatively (baseline) and at 1, 3, 6, 8, 12 and 24 h after extubation. Venous blood was collected at baseline, and 12 and 24 h after the administration of carprofen or grapiprant to perform a complete blood count (CBC), the percentage of Heinz bodies and serum biochemistry (alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, gamma-glutamyltransferase, creatinine and urea). Urinalysis was performed at baseline and 24 h after extubation. Glucose levels were evaluated at baseline and 1 h postoperatively. Results Pain scores were not significantly different among groups in both scales, although pain was higher at 3 h in comparison with 24 h in all groups. In the GRA1 and GRA2 groups, 67% (14/21) of cats needed rescue analgesia compared with 18% (2/11) in the CAR group. Glucose increased from baseline to 1 h in the GRA1 and GRA2 groups. None of the CBC, serum biochemistry and urinalysis variables differed among groups. Conclusions and relevance Grapiprant did not promote adequate analgesia during the first 3 h postoperatively in cats undergoing ovariohysterectomy compared with carprofen, and no benefits were observed by administering grapiprant every 12 h.
The relationship between processing speed and verbal and non-verbal new learning and memory in progressive multiple sclerosis
Authors: Chiaravalloti Nancy D , DeLuca John , Salter Amber , Amato Maria Pia , Brichetto Giampaolo , Chataway Jeremy , Dalgas Ulrik , Farrell Rachel , Feys Peter , Filippi Massimo , Freeman Jennifer , Inglese Matilde , Meza Cecilia , Moore Nancy B , Motl Robert W , Rocca Maria Assunta , Sandroff Brian M , Cutter Gary , Feinstein Anthony 
Published: May 2022

Objective: Processing speed (PS) deficits are the most common cognitive deficits in multiple sclerosis (MS), followed by learning and memory deficits, and are often an early cognitive problem. It has been argued that impaired PS is a primary consequence of MS, which in turn decreases learning. The current analysis examined the association between PS and learning in a large cohort of individuals with progressive MS. Methods: Baseline data from a randomized clinical trial on rehabilitation taking place at 11 centers across North America and Europe were analyzed. Participants included 275 individuals with clinically definite progressive MS (primary, secondary) consented into the trial. Results: Symbol Digit Modalities Test (SDMT) significantly correlated with California Verbal Learning Test-II (CVLT-II) ( r = 0.21, p = 0.0003) and Brief Visuospatial Memory Test–Revised (BVMT-R) ( r = 0.516, p < 0.0001). Receiver operating characteristic (ROC) analysis of the SDMT z score to distinguish between impaired and non-impaired CVLT-II performance demonstrated an area under the curve (AUC) of 0.61 (95% confidence interval (CI): 0.55–0.68) and a threshold of −1.62. ROC analysis between SDMT and BVMT-R resulted in an AUC of 0.77 (95% CI: 0.71–0.83) and threshold of −1.75 for the SDMT z score to predict impaired BVMT-R. Conclusion: Results indicate little ability beyond chance to predict CVLT-II from SDMT (61%), albeit statistically significant. In contrast, there was a 77% chance that the model could distinguish between impaired and non-impaired BVMT-R. Several potential explanations are discussed.
A paired comparison of nerve dimensions using B-Mode ultrasound and shear wave elastography during regional anaesthesia
Authors: Lockwood Heather , McLeod Graeme A 
Published: May 2022

Introduction: Shear wave elastography (SWE) presents nerves in colour, but the dimensions of its colour maps have not been validated with paired B-Mode nerve images. Our primary objective was to define the bias and limits of agreement of SWE with B-Mode nerve diameter. Our secondary objectives were to compare nerve area and shape, and provide a clinical standard for future application of new colour imaging technologies such as artificial intelligence. Materials and Methods: Eleven combined ultrasound-guided regional nerve blocks were conducted using a dual-mode transducer. Two raters outlined nerve margins on 110 paired B-Mode and SWE images every second for 20 s before and during injection. Bias and limits of agreement were plotted on Bland-Altman plots. We hypothesized that the bias of nerve diameter would be <2.5% and that the percent limits of agreement would lie ±0.67% (2 SD) of the bias. Results: There was no difference in the bias (95% confidence interval (CI) limits of agreement) of nerve diameter measurement, 0.01 (−0.14 to 0.16) cm, P = 0.85, equivalent to a 1.4% (−56.6% to 59.5) % difference. The bias and limits of agreement were 0.03 (−0.08 to 0.15) cm2, P = 0.54 for cross-sectional nerve area; and 0.02 (−0.03 to 0.07), P = 0.45 for shape. Reliability (ICC) between raters was 0.96 (0.94–0.98) for B-Mode nerve area and 0.91 (0.83–0.95) for SWE nerve area. Conclusions: Nerve diameter measurement from B-Mode and SWE images fell within a priori measures of bias and limits of agreement.
Spray response on a model prefilmer under unsteady airflows of various frequencies
Authors: Christou Thomas , Stelzner Björn , Zarzalis Nikolaos 
Published: May 2022

An appealing concept for jet engine combustors is the Lean Premixed Prevaporized (LPP) combustor, which operates at high pressures. The low NOx emissions achieved by lean combustion are one of the targets for modern aircraft engines. However, these types of combustors can introduce thermoacoustic instabilities that can potentially damage the engine and reduce its lifespan. Since the potential instabilities on the fuel spray characteristics, i.e. the spray mass flux, can affect the flame stability, the need arises to investigate the spray response under an unsteady airflow. For this study, a model prefilmer was experimentally investigated to produce a two-dimensional droplet flow without swirl flow. An acoustic forcing in the range of 100–500 Hz was introduced into the airflow, characterized by a hot wire Constant Temperature Anemometry (CTA) setup. Droplet characteristics, namely the droplet diameter distribution and velocity, were determined using a Phase Doppler Anemometry (PDA) setup, while the acquired data were phase-averaged in one period of the airflow oscillation. The influence of the excitation frequency and the air-to-liquid ratio (ALR) on the spray was studied: the spray responded to the acoustic excitation and therefore critical performance parameters, such as the spray mass flux, oscillated indicating potential problems regarding the flame stability.
Can a Basic Management App Paired With A Glucose Meter Help Reduce Glucose Levels Among Adults With Type 2 Diabetes? The REALL Study
Authors: Fisher Lawrence , Fortmann Addie , Knaebel Jennifer , Stuhr Andreas 
Published: May 2022

Objective: Evaluations of technology to help adults manage type 2 diabetes (T2D) have yielded mixed results. We analyzed the effectiveness of a free app linked to a glucose meter to study reductions in glucose levels over time among a self-selected sample of adults with T2D. Research Design and Methods: Adults with T2D >12 months, >21 years, ability to read English (insulin using—IU and non-insulin using—NIU) who independently elected to pair their CONTOUR NEXT ONE meter with the CONTOUR DIABETES App were invited to participate. Glucose data from baseline to 16 weeks were uploaded to the cloud (N = 461). Assessment of diabetes distress, medication taking, quality of life, and hypoglycemia concerns occurred at baseline, six, and 16 weeks. Results: Findings indicated a significant decrease in weekly glucose levels over time: baseline mean = 169 (62.0) (9.4 mmol/L; 3.44); 16-week mean = 146.5 (36.0) (8.1 mmol/L; 2.0) ( P < .001), with no IU and NIU differences. Largest reductions occurred during the first six weeks, with no later rebound effects. Significant, though modest, improvements in global quality of life ( P = .03), hypoglycemia concerns ( P = .01), and diabetes distress ( P < .001) occurred over 16 weeks. Conclusions: Making an App for monitoring glucose easily available for download with a glucose meter can be helpful for self-selected adults with T2D. Effective utilization assumes that users are sufficiently motivated and engaged, are comfortable and trusting of the technology, and have sufficient knowledge of how to make use of the glucose data.
Conducting organizational survey and experimental research online: From convenient to ambitious in study designs, recruiting, and data quality
Authors: Van Quaquebeke Niels , Salem Mojtaba , van Dijke Marius , Wenzel Ramon 
Published: May 2022

Conducting organizational research via online surveys and experiments offers a host of advantages over traditional forms of data collection when it comes to sampling for more advanced study designs, while also ensuring data quality. To draw attention to these advantages and encourage researchers to fully leverage them, the present paper is structured into two parts. First, along a structure of commonly used research designs, we showcase select organizational psychology (OP) and organizational behavior (OB) research and explain how the Internet makes it feasible to conduct research not only with larger and more representative samples, but also with more complex research designs than circumstances usually allow in offline settings. Subsequently, because online data collections often also come with some data quality concerns, in the second section, we synthesize the methodological literature to outline three improvement areas and several accompanying strategies for bolstering data quality. Plain Language Summary: These days, many theories from the fields of organizational psychology and organizational behavior are tested online simply because it is easier. The point of this paper is to illustrate the unique advantages of the Internet beyond mere convenience—specifically, how the related technologies offer more than simply the ability to mirror offline studies. Accordingly, our paper first guides readers through examples of more ambitious online survey and experimental research designs within the organizational domain. Second, we address the potential data quality drawbacks of these approaches by outlining three concrete areas of improvement. Each comes with specific recommendations that can ensure higher data quality when conducting organizational survey or experimental research online.
Residual Effects of Glenohumeral Range of Motion, Strength, and Humeral Retroversion on Prior Overhead Athletes After Cessation of Sport
Authors: Talmage Jessica L. Downs , Cramer Abigail M. , Oliver Gretchen D. 
Published: May 2022

Background: Research has shown that repetitive stress from playing an overhead (OH) sport can cause musculoskeletal and osseous adaptations to occur on the dominant side. Additionally, there are limited data about the residual effects of these adaptations after the cessation of sports participation. Purpose: To investigate the effects of prior participation in an OH sport versus not participating in an OH sport on glenohumeral range of motion (ROM), isometric strength, and humeral retroversion (HR). Study Design: Cross-sectional study; Level of evidence, 3. Methods: Forty-eight college-aged individuals participated. Participants were split into 2 groups: (1) individuals who previously participated in an OH sport (n = 20; age, 20.3 ± 1.1 years; height, 166.3 ± 15.27 cm; weight, 72.2 ± 13.5 kg) and (2) individuals who previously did not play an OH sport (n = 28; age, 20.6 ± 0.9 years; height, 168.8 ± 6.3 cm; weight, 68.1 ± 15.1 kg). After completing a health history questionnaire, the following were measured: side-to-side shoulder internal rotation (IR) and external rotation (ER) ROM via an inclinometer, isometric shoulder strength via a handheld dynamometer, and HR using an ultrasound imaging machine. A Mann-Whitney U test was used to determine group differences, and a Wilcoxon t test was used to analyze side-to-side differences within each group. Results: The Mann-Whitney U test revealed a statistically significant group difference for dominant shoulder ER ROM ( U = 162.00, P = .014). Specifically, the prior OH group had significantly more ER than the control group. Within the prior OH group, testing revealed that athletes had significantly more HR ( Z =–2.782, P = .005), ER ROM ( Z =–1.979, P = .048), and ER isometric strength ( Z =–2.763, P = .006) on their dominant than nondominant shoulder and significantly less IR ROM ( Z =–3.099, P = .002) on their dominant than nondominant shoulder. Conclusion: Prior OH sports participation may have residual osseous and musculoskeletal effects that remain after cessation of the sport.