bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation an Aqueous Extract of Irradiated and Non Irradiated of Orthosiphon Aristatus on Zebrafish Embryo (Danio Rerio) through Acute Toxicity Assay
Authors: Balan Santhra Segaran , Manokaram Punithaamalar , Maya Sitell , Bahari Hasnah , Uzid Mahathir Mohd , Muhammad Danial Muhammad Danial , Abidin Azrina Zainal , Jesus Arapoc Daryl , Rahmadi Mahardian 
Published: June 2022

Background: Orthosiphon aristatus has been usually related to be powerful in curing many illnesses inclusive of post-partum remedy, anti-influence, rheumatism and stopping osteoporosis as a result of menopause. Objectives: Thus, this study was designed to differentiate the toxicity effect of non-irradiated and irradiated Orthosiphon aristatus at different dosage of 3, 6, 9 and 12 kilogray (kGy) on zebrafish embryo. Method: Survival rate, hatching rate, heart beat rate and scoliosis were observed and date were analysed using SPSS 25.00 windows. Result: The lethal dose (LC50) of non-irradiated Orthosiphon aristatus is 381.81 μg/mL compare to irradiated extract at 3 % is (371.27 μg/mL), 6 % (311.03 μg/mL), 9 % (160.72 μg/mL) and 12 % (140.18 μg/mL). Hatchability of zebrafish embryo for Orthosiphon aristatus extract decrease in the higher dosage of irradiated sample compared to non-irradiated sample. No presence of scoliosis was observed in all dosage of irradiated and non-irradiated of Orthosiphon aristatus. The heartbeat of zebrafish embryo treated with irradiated Orthosiphon aristatus specifically 12 % show decrease at 250 μg/mL concentration. Remaining dosage of irradiated and non-irradiated Orthosiphon aristatus show average heartbeat around 120 - 160 bpm. Conclusion: As conclusion, irradiated and non-irradiated of Orthosiphon aristatus is safe to be consumed due to its pharmaceutical effect but it still exhibited mild toxicity effect on zebrafish embryo.
HIGHLIGHTS

Herbal medicine (Orthosiphon aristatus) is widely used for treatment as alternative medicine
This Orthosiphon aristatus easy can be contaminated by bacteria and fungus. Gamma ray is helpful to eliminated the bacteria and fungus
Irradiated Orthosiphon aristatus can be toxic due to the exposure in Gamma ray
Toxicity study using zebra fish show no changes in toxicity of Orthosiphon aristatus

GRAPHICAL ABSTRACT
Participation in Daily Activities Among Women 5 Years After Breast Cancer
Authors: Loubani Khawla , Schreuer Naomi , Kizony Rachel 
Published: June 2022

Abstract
Importance: Understanding the long-term participation restrictions after breast cancer (BC) is crucial for developing occupation-based interventions.
Objective: To (1) compare women’s participation during the BC subacute phase (2 yr postdiagnosis) with the chronic (5 yr postdiagnosis) phase, (2) explore factors associated with participation in the chronic phase, and (3) describe strategies women use to overcome participation restrictions.
Design: Descriptive longitudinal study.
Setting: A community health service in Israel.
Participants: A convenience sample of 30 women (M age = 53.9 yr, SD = 8.3) diagnosed with BC (Stages 1–3).
Outcomes and Measures: Demographic and BC–related symptom questionnaires; an adapted version of the Activity Card Sort, used to assess retained activity levels (RALs) compared with prediagnosis activity levels in sociocultural, physical, and instrumental domains; the Canadian Occupational Performance Measure; and one open-ended qualitative question, “How were you able to retain your participation in daily activities despite the long-term effects of BC?”
Results: Significantly higher total RALs were found in most domains for women in the chronic (M = 0.93 RAL, SD = 0.27) compared with the subacute (M = 0.71, SD = 0.22) phase, t(29) = 4.72, p &lt; .001. Almost half the women achieved clinically significant change in their meaningful activities. Lower levels of participation were significantly correlated with higher symptom severity. The qualitative findings indicated that coping strategies, such as positive thinking and changing priorities, helped in managing women’s participation.
Conclusions and Relevance: Participation restrictions and residual BC-related symptoms 5 yr postdiagnosis demonstrated the need for a comprehensive evaluation and early occupational therapy intervention to prevent long-term restrictions.
What This Article Adds: This study highlights the value of a comprehensive assessment of daily participation (i.e., participation in various activity domains and in specific individual meaningful activities) of women with BC. The combination of quantitative and qualitative analysis provided a subjective perspective and deeper understanding of the associations among long-term symptoms, participation restrictions, and coping strategies.
Model Recurent Neural Network untuk Peramalan Produksi Tebu Nasional
Authors: Kustiyo Aziz , Mukhlis Mukhlis , Suharso Aries 
Published: June 2022

Abstrak: Produksi tebu di Indonesia tersebar di beberapa wilayah yang mengakibatkan variabilitas yang tinggi dari variabel-variabel yang mempengaruhi produksi tebu nasional. Di samping itu, tidak mudah untuk mendapatkan data-data tersebut dalam waktu yang cukup panjang. Oleh karena itu peramalan produksi tebu nasional berdasarkan variabel-variabel tersebut sangat sulit dilakukan. Sebagai solusi dari masalah tersebut, maka peramalan produksi tebu nasional dilakukan berdasarkan data historisnya. Penelitian ini bertujuan untuk mengembangkan model recurrent neural networks (RNN) untuk peramalan produksi tebu nasional berdasarkan data historisnya. Data yang digunakan adalah data produksi tebu nasional dari tahun 1967 sampai dengan tahun 2019 dalam satuan ton. Sebagai data latih digunakan data tahun 1967 sampai dengan tahun 2006 dan sisanya dipakai sebagai data uji. Pada penelitian ini dilakukan percobaan untuk mengetahui pengaruh panjang deret waktu dan ukuran batch terhadap kinerja model RNN dengan tiga ulangan. Hasil penelitian menunjukkan bahwa model RNN dengan panjang deret waktu 4 dan ukuran batch 16 menghasilkan nilai mean absolut percentage error (MAPE) sebesar 9.0% dengan nilai korelasi 0.77. Secara umum, model RNN yang dibangun mampu menangkap pola produksi tebu nasional dengan tingkat kesalahan yang masih dapat ditoleransi.

Kata kunci: deret waktu, peramalan, produksi tebu, recurrent neural networks

Abstract: Sugarcane production in Indonesia is spread over several regions. This condition results in high variability of the variables that affect national sugarcane production. In addition, it is not easy to obtain these data over a long period. As a result, it is very difficult to forecast the production of national sugarcane based on the influencing variables. Therefore, the forecasting was based on historical data of the national sugarcane production. This study aims to develop a recurrent neural networks (RNN) model for forecasting national sugarcane production based on historical data. The data used is national sugarcane production data from 1967 to 2019 in tons. As training data, data from 1967 to 2006 were used and the rest was used as test data. In this study, an experiment was conducted to determine the effect of time series length and batch size on the performance of the RNN model with three replications. The results showed that the RNN model with a time series length of 4 and a batch size of 16 produced a mean absolute percentage error (MAPE) of 9.0% with a correlation value of 0.77. In general, the RNN model is able to capture the national sugarcane production pattern with a tolerable error rate.

Keywords: forecasting, recurrent neural networks, sugarcane production, time series
Les facteurs prédictifs de thrombose au cours de la procédure d’autogreffe de cellules souches au cours du myélome multiple (MM): Expérience de l’EHU Oran.
Authors: Boukerche Farouk , Hammou Leiila , Laredj Nadia 
Published: June 2022

Introduction :
Le risque de thromboses au cours des cancers est environ de 7% et est plus élevé au cours du MM. L’objectif de notre travail est d’évaluer l’incidence de la thrombose, mais également d’en rechercher les facteurs prédictifs au cours de la procédure d’autogreffe des cellules souches hématopoïétiques au cours de la vraie vie.
Matériels et méthodes :
Il s’agit d’une étude rétrospective (Mai 2009-31 Décembre 2019). Le diagnostic de thrombose est posé devant des signes et des symptômes cliniques de thrombose et confirmé par un écho doppler du site de localisation concerné ou un angio-scanner, en cas de suspicion d’une embolie artérielle et du point de vue biologique par l’élévation des D-Dimères. L’évaluation a porté sur l’incidence globale des thromboses et la détermination des facteurs prédictifs suivants : âge, les comorbidités, l’utilisation des immunomodulateurs (IMiDs), l’utilisation du G-CSF au cours de la mobilisation et de la phase d’aplasie, le site d’insertion du KT central ainsi que sa durée, le nombre de cytaphérèse, le taux de CD34+ perfusées et enfin la prophylaxie de la TVP par une héparine de bas poids moléculaire (HBPM). L’analyse statistique a été réalisée à l’aide du test du Khi2 ou de Fisher.
Résultats :
411 patients ont été colligés, dont 249 hommes avec un sexe ratio de 1,53. L’incidence globale de la thrombose est de 18.49% (76 patients). Les facteurs prédictifs retrouvés sont l’utilisation des IMiDs (p=0,0006), le site d’insertion fémorale du KTC (p=0,021) et sa durée (p=0,018), le taux de G-CSF?15µg/kg (0,014) au cours de la mobilisation, le nombre de CD34+ perfusées> 5x106/kg (p=0.035) et la prophylaxie avec les HBPM (p=0.029).
Conclusion :
L’incidence globale de thrombose est semblable à celle rapportée dans la littérature. La prophylaxie par HBPM est indispensable dans la prévention de la thrombose au cours du MM.
Mots clés :
Autogreffe de CSH, facteurs prédictifs, myélome multiple, thrombose.
Lessons from the 2018–2019 European droughts: a collective need for unifying drought risk management
Authors: Blauhut Veit , Stoelzle Michael , Ahopelto Lauri , Brunner Manuela I. , Teutschbein Claudia , Wendt Doris E. , Akstinas Vytautas , Bakke Sigrid J. , Barker Lucy J. , Bartošová Lenka , Briede Agrita , Cammalleri Carmelo , Kalin Ksenija Cindrić , De Stefano Lucia , Fendeková Miriam , Finger David C. , Huysmans Marijke , Ivanov Mirjana , Jaagus Jaak , Jakubínský Jiří , Krakovska Svitlana , Laaha Gregor , Lakatos Monika , Manevski Kiril , Neumann Andersen Mathias , Nikolova Nina , Osuch Marzena , van Oel Pieter , Radeva Kalina , Romanowicz Renata J. , Toth Elena , Trnka Mirek , Urošev Marko , Urquijo Reguera Julia , Sauquet Eric , Stevkov Aleksandra , Tallaksen Lena M. , Trofimova Iryna , Van Loon Anne F. , van Vliet Michelle T. H. , Vidal Jean-Philippe , Wanders Niko , Werner Micha , Willems Patrick , Živković Nenad 
Published: June 2022

Abstract. Drought events and their impacts vary spatially and temporally due to diverse pedo-climatic and hydrologic conditions, as well as variations in exposure and vulnerability, such as demographics and response actions. While hazard severity and frequency of past drought events have been studied in detail, little is known about the effect of drought management strategies on the actual impacts and how the hazard is perceived by relevant stakeholders. In a continental study, we characterised and assessed the impacts and the perceptions of two recent drought events (2018
and 2019) in Europe and examined the relationship between management
strategies and drought perception, hazard, and impact. The study was based on a pan-European survey involving national representatives from 28 countries and relevant stakeholders responding to a standard questionnaire. The survey focused on collecting information on stakeholders' perceptions of drought, impacts on water resources and beyond, water availability, and current drought management strategies on national and regional scales. The survey results were compared with the actual drought hazard information registered by the European Drought Observatory (EDO) for 2018 and 2019. The results highlighted high diversity in drought perception across different countries and in values of the implemented drought management strategies to alleviate impacts by increasing national and sub-national awareness and resilience. The study identifies an urgent need to further reduce drought impacts by constructing and implementing a European macro-level drought governance approach, such as a directive, which would strengthen national drought management and mitigate damage to human and natural assets.
An Empirical Study of Autonomous Medical Institution to Identify the Role of Human Resources Practices on Perceived Employees Performance in Punjab, Pakistan
Authors: Rao Muhammad Rashad Qamar , Aleem Muhammad , Ullah Muhammad Imdad 
Published: June 2022

This study gauges the associations between Human Resource (HR) practices and the perceived performance of employees at Autonomous medical institutions'(AMI), Punjab (Pakistan). The HR practices thrashed out in this study are Recruitment & Selection, Training & Development, Compensation, complaint resolutions procedure, and Job clarity. 220 respondents were selected randomly from the 13 AMI’s of Punjab. The data was collected through a personally administered questionnaire. A personally administered questionnaire was used to obtain the data. The study's findings demonstrate that in the health sector, recruitment and selection, training and development, salary, and job clarity all have a substantial association with employee performance, but the complaint resolution method has no such relationship. The study provided a strategic tool for the improvement of employee performance by using these practices.
Validating a parking lot assignment method by Eclipse SUMO
Authors: Alekszejenkó Levente , Dobrowiecki Tadeusz 
Published: June 2022

The present paper shows how a novel autonomous vehicle (AV) algorithm can be tested and evaluated by multiple simulations with different levels of refinement.
As the first AVs will appear on our roads (possibly) within the upcoming decade, novel traffic problems, like parking lot assignment, will also emerge. Parking is that kind of activity that will fundamentally change. Today drivers attempt to find parking places close to the destinations to minimize the walking time. The autonomous vehicles will drop off passengers at their very destination, and then, on their own, will seek even a distant parking place. Such change will affect human activities, city traffic, and the parking infrastructure.
To investigate this problem we need an abstract city model, because an attempt to create a detailed model of the city traffic from the perspective of decades may be misleading and may lead to false emergent conclusions. We report on such an abstract model and the obtained conclusions in the paper.
A question remains how genuine is the introduced future city model. To validate it, we propose to confront it with a detailed microscopic traffic simulation on a road network borrowed from an existing city of corresponding layout and complexity. To this end, we use Eclipse SUMO simulating the traffic of an expansive Budapest district, and show that the results obtained with the simplified abstract mathematical model stay valid.
Trend of Perioperative CRP (C-Reactive Protein) Levels in Non-Infected Total Knee Arthroplasty
Authors: Mercurio Michele , Galasso Olimpio , Familiari Filippo , Iannò Bruno , Bruno Carmine Fabio , Castioni Davide , Gasparini Giorgio 
Published: June 2022

The aim of this prospective study was to define the perioperative trend of C-reactive protein (CRP) in non-infected total knee arthroplasty (TKA). CRP was evaluated in 42 patients the day before surgery and 4 and 30 days after surgery. Functional and radiological evaluation was scheduled for 3, 6, and 12 months after surgery. Preoperatively, the median CRP was 3.2 mg/L (IQR,3.2-4.2) (reference range, 0-5 mg/L); 4 and 30 days after surgery, it measured 57.6 mg/L (IQR,36.1-96.4) and 5.3 mg/L (IQR,3.0-11.8), respectively. There were significant differences between the CRP preoperatively and 4 days after surgery (p<0.001) and between CPR levels 4 and 30 days after surgery (p<0.001) but not between CRP values preoperatively and 30 days after surgery (p=0.181). Higher preoperative CRP was associated to heart disease and chronic renal failure (r=0.329, p=0.036, and r=0.437, p=0.004, respectively). Four days after surgery, higher CRP was associated to older patients (r=0.311, p=0.048). In summary, 30 days after primary non-infected TKA, CRP levels were comparable to preoperative values. Older age and comorbidities should be carefully evaluated using postoperative CRP as diagnostic marker for the early detection of infection.
İslam Dünyasında Hicri Birinci Yüzyıldan Günümüze Kadar Aşere Kıraatinin Yayılmasının Tarihsel Aşamaları
Authors: NAROL Süleyman , FATTAHI Huda 
Published: June 2022

İlahi vahyin beşeri lisana bürünmüş hali olan Kur'an'ın anlaşılması ve yorumlanması konusunda Hz. Peygamber, sahabe ve tâbiûn tarafından bir takım usul ve esaslar ortaya konulmuştur. Sonraki dönemlerde de âlimler bu esaslar üzerine her dönemin ihtiyacına göre yeni bir takım ilavelerde bulunmuşlardır. Kur'an'ın anlaşılmasına dair bu usul ve kaideler dinamik bir şekilde asrısaadetten günümüze kadar gelmiştir. Kur'an'ın doğru bir şekilde anlaşılması ve yorumlanmasına dair bu usul ve esasları ele alan Kur'an ilimleri içerisinde kıraat ilmi en önde gelen ilimler arasında yer alır. Kıraat ilminin haiz olduğu bu önem sebebiyle Kur'an’ı anlama ve yorumlama çabası içerisinde bulunan müfessirlerce geçmişten günümüze tarihin her aşamasında kendisine yeterince ilgi gösterilmiş ve bu ilim bütün İslam coğrafyasında nesilden nesile aktarılmıştır. Ancak kıraat ilmine gösterilen bu ilgiye rağmen ne yazık ki bu ilmin tarihi süreçte İslam coğrafyasında yayılmasını ele alan ve onun tarihçesine yer veren kaynakların oldukça sınırlı olduğu görülmektedir. Kadim dönemden modern döneme âlimlerinin tasnif ettikleri eserlerinde bazı kıraatlerin İslam âleminde belli tarihsel aşamalarda nasıl yayıldığı veya yok olduğu ya da İslam âlemindeki coğrafi dağılımının nasıl olduğu ile ilgili hususlarsa dair yeterli bilgi bulmak pek mümkün değildir.
Bu makale, hicri birinci asırdan günümüze kadar geçen zaman diliminde İslam dünyasının tamamında kıraatlerin yayılış serüvenini ele almayı amaçlamıştır. Özellikle Mekke, Medine, Şam, Kufe, Basra, Mısır, Kuzey Afrika, Endülüs ve Anadolu vb. bölgelerde yayılan kıraatlerin Hicri birinci yüzyıldan günümüze kadarki gelişimi ve bir ülkeden diğer bir ülkeye yayılma sürecini tetikleyen sebeplere ve bir zaman diliminden diğerine geçerken kat ettiği mesafeye yer vermeyi hedeflemiştir. Kıraatlerin yayılmasının sebepleri üzerinde durulurken de bu sebeplerin öne çıkanlarının, kârilerin sahip olduğu şöhret, bu alanda ortaya koydukları etkin faaliyetler, kıraatlerin sahip olduğu özellikler ile siyasi veya mezhepsel motifler olduğu tespiti yapılmış ve bunlar üzerinde durulmuştur.
Kıraat ilminin Kur'an ilimleri içerisinde sahip olduğu önem ve kendisine gösterilen ilgiye rağmen aşere kıraatinin tarihi süreçte kat ettiği aşamaları ele alan çok fazla çalışma bulunmadığından bu çalışma söz konusu boşluğu bir nebze de olsa doldurmayı amaçlamıştır.
4MAT Öğrenme Stillerine Uygun Olarak Seçilen Öğrenme Yöntemlerinin Matematik Öğretmen Adaylarının Açık Uçlu Problem Çözmedeki Başarısına Etkisi
Authors: ELÇİ Aysun Nüket 
Published: June 2022

Bu çalışmanın 4MAT öğrenme stillerine uygun olarak seçilen öğrenme yöntemlerinin matematik öğretmen adaylarının açık uçlu problem çözme başarısı ve problem çözmenin veri, model, çözüm ve geliştirme alt basamakları üzerinde etkisini ortaya çıkarmaktır. Çalışmada tek gruplu ön test-son test modeline dayalı deneysel yöntem kullanılmıştır. Çalışmanın katılımcıları ortaöğretim matematik öğretmeni adaylarından oluşmaktadır. Veri toplama aracı olarak türev ile ilgili kazanımları içeren ara sınav ve dönem sonu sınavlarında sorulan açık uçlu problemler kullanılmıştır. Açık uçlu problemlerin değerlendirilmesinde problemin veri toplama, modelleme, modellemenin çözülmesi ve problemin genişletilmesi basamaklarını içeren araştırmacılar tarafından geliştirilen dereceli puanlama anahtarı yardımıyla elde edilmiştir. Çalışmanın verilerin analizi ile 4MAT öğrenme stillerine uygun olarak seçilen öğrenme yöntemlerinin matematik öğretmen adaylarının açık uçlu problem çözmedeki başarısı, problem çözme basamaklarından veri, model, çözüm ve geliştirme basamakları üzerinde etkisi olduğu sonucuna ulaşılmıştır. Matematik öğretmen adaylarının problem çözmenin ilk aşaması olan veri basamağında tamamının ve problem çözmenin diğer basamakları olan modeli çözüm ve geliştirme basamaklarındaki tamamına yakınının gelişme göstermiştir. Yıllarca bilgi ve işleme dayalı testten başarılı olmaya alışan öğretmen adaylarının aşina olmadıkları açık uçlu sorulara rağmen gösterdikleri gelişme gelecekte mesleklerinde de gelişime açık olacaklarının dolayısıyla başarılı olacaklarının da bir göstergesidir.
Anahtar Kelimeler: 4 MAT, öğrenme stilleri, türev.
Traffic sign detection and recognition based on convolutional neural network
Authors: Saraswathy C , Nandhini K , Kalaivani R 
Published: June 2022

Traffic sign detection is one of the critical technologies in the field of intelligent transportation systems (ITS). The difficulty of traffic sign detection mainly lies in detecting small objects in a wide and complex traffic scene quickly and accurately. To develop an efficient traffic sign detection and recognition that can detect and categorize traffic signal into different classes in real-time with the help of Deep Learning techniques. In this project, regard traffic sign detection as a region classification problem and propose a two-stage R- CNN-based approach to solve it. To build a deep neural Network model that can classify traffic sign present in images into different categories. The training process takes predefined traffic signals and has them 'learn' into a model. With this model, people are able to read and understand traffic signs which are a very important task for all autonomous vehicles. A visual traffic sign recognition system can be integrated into the automobile with the objective of detecting and recognizing all emerging traffic signs. In case the driver refuses to heed traffic signs, the system will trigger an alarm.
Reducing operating costs approaches of subcontractors in Thai construction industry
Authors: Horadal Pong , Hanathanchuchot Thanakorn , Laochai Sawat 
Published: June 2022

This research aim to 1).compare the important level of operating factors of subcontractor companies in construction industry classifier by general information of respondents 2) Finding reducing operating costs approaches of subcontractors in Thai construction industry. The research found that:1)there was not significant different of the important level of operating factors of subcontractor companies in construction industry classifier by position, age rage, work experience of respondents. 2) the reducing operating costs approaches of subcontractors in Thai construction industry were reduce the waste of inventory, transportation does not add value, defects from construction work, waiting time, non-utilized talent employees, motion of employees, these factors jointly prophesy 60.1 % , at statistical significance level of .05.