bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bodies in Cinema: Evaluating Operationalisations of Closeness to Movie Characters
Authors: Suckfüll Monika 
Published: January 2022

Abstract
Based on theoretical considerations on embodied affectivity in social life, the feeling of being close is argued to be pivotal for experiencing one-sided interactions with movie characters. Currently, a feasible methodology to be used in order to measure this variable is still missing. A subsample (n = 14) from existing data is used to evaluate three operationalisations of closeness to the main character in two central scenes of the movie Sehnsucht by Valeska Grisebach: (1) Closeness as grades of familiarity is operationalised using a pictorial measure with the participant indicating which of two more or less overlapping circles (one representing the self, one representing the screen character) describes the relationship best. (2) Physical closeness is assessed with recordings of the eye movements which provide a fine-grained measurement of distance to the screen. (3) Closeness as synchronicity could be observed by analysing the facial expressions and movements of the participant in front of the screen simultaneously with the expressions and movements of the movie characters. The results of the study point to limitations of an operationalisation of closeness as familiarity by using a single-item measurement. Furthermore, with synchronicity being rarely observed, this way of being close appears to be a phenomenon of minor relevance for movie reception. The measurement of physical closeness, however, indicates a promising approach due to behavioural patterns being detectable and easily interpretable in accordance with the movie’s content. Ideas for further methodological development of an operationalisation of physical closeness are proposed.
Review of the genus Woznessenskia Gorochov, 2002 (Orthoptera: Gryllacrididae) from China
Authors: SHI FU-MING , ZHU QI-DI , WANG HAI-JIAN 
Published: January 2022

The paper reports four new species of the genus Woznessenskia Gorochov, 2002 and gives supplementary information on Woznessenskia curvicauda (Bey-Bienko, 1962) from China. The specimens examined are deposited in the Museum of Hebei University, Baoding, China.
Turbulent Parameters in the Middle Atmosphere: Theoretical Estimates Deduced from a Gravity Wave–Resolving General Circulation Model
Authors: Avsarkisov Victor , Becker Erich , Renkwitz Toralf 
Published: January 2022

Abstract
We present a scaling analysis for the stratified turbulent and small-scale turbulent regimes of atmospheric flow with emphasis on the mesosphere. We distinguish rotating-stratified macroturbulence turbulence (SMT), stratified turbulence (ST), and small-scale isotropic Kolmogorov turbulence (KT), and we specify the length and time scales and the characteristic velocities for these regimes. It is shown that the buoyancy scale (Lb) and the Ozmidov scale (Lo) are the main parameters that describe the transition from SMT to KT. We employ the buoyancy Reynolds number and horizontal Froude number to characterize ST and KT in the mesosphere. This theory is applied to simulation results from a high-resolution general circulation model with a Smagorinsky-type turbulent diffusion scheme for the subgrid-scale parameterization. The model allows us to derive the turbulent root-mean-square (rms) velocity in the KT regime. It is found that the turbulent RMS velocity has a single maximum in summer and a double maximum in winter months. The secondary maximum in the winter MLT we associate with a secondary gravity wave–breaking phenomenon. The turbulent rms velocity results from the model agree well with full correlation analyses based on MF-radar measurements. A new scaling for the mesoscale horizontal velocity based on the idea of direct energy cascade in mesoscales is proposed. The latter findings for mesoscale and small-scale characteristic velocities support the idea proposed in this research that mesoscale and small-scale dynamics in the mesosphere are governed by SMT, ST, and KT in the statistical average.

Significance Statement
Mesoscale dynamics in the middle atmosphere, which consists of atmospheric turbulence and gravity waves, remains a complex problem for atmospheric physics and climate studies. Due to its high nonlinearity, the mesoscale dynamics together with the small-scale turbulence is the primary source of uncertainties and biases in high-altitude general circulation models (GCM) in the middle atmosphere. We use the stratified turbulence theory and the gravity wave–resolving GCM to characterize different scaling regimes and to define various length, time, and velocity scales, that are relevant for the mesoscale and small-scale dynamical regimes. Our results highlight the importance of stratified turbulence in the mesosphere and lower-thermosphere region.
Vertical Wind Tunnel Experiments and a Theoretical Study on the Microphysics of Melting Low-Density Graupel
Authors: Theis Alexander , Szakáll Miklós , Diehl Karoline , Mitra Subir K. , Zanger Florian , Heymsfield Andrew , Borrmann Stephan 
Published: January 2022

Abstract
Vertical wind tunnel experiments were carried out to investigate the melting of low-density lump graupel while floating at their terminal velocities. The graupel characteristics such as maximum dimension, density, and axis ratio were 0.39 ± 0.06 cm, 0.41 ± 0.07 g cm−3, and 0.89 ± 0.06. The airstream of the wind tunnel was gradually heated simulating lapse rates between 4.5 and 3.21 K km−1. Each experimental run was performed at a constant relative humidity that was varied between 12% and 92% from one experiment to the other. From the image processing of video recordings, variations in minimum and maximum dimension, volume, aspect ratio, density, volume equivalent radius, and ice core radius were obtained. New parameterizations of the terminal velocity prior to melting and during melting were developed. It was found that mass and heat transfer in the dry stage is 2 times as high as that of liquid drops at the same Reynolds number. Based on the experimental results, a model was developed from which the external and internal convective enhancement factors during melting due to surface irregularities and internal motions inside the meltwater were derived using a Monte Carlo approach. The modeled total melting times and distances deviated by 10% from the experimental results. Sensitivity tests with the developed model revealed strong dependencies of the melting process on relative humidity, lapse rate, initial graupel density, and graupel size. In dependence on these parameters, the total melting distance varied between 600 and 1200 m for typical conditions of a falling graupel.

Significance Statement
The accuracy of weather forecast models to predict precipitation depends strongly on the representation of cloud processes in those models. Heavy rain events are mostly the result of melting ice particles. Furthermore, melting affects the storm characteristics and its destructive potential. In this study, we investigated the melting of low-density graupel, which constitute an important class of precipitation particles. Our experiments in a vertical wind tunnel under close to atmospheric conditions indicated an increased melting rate of graupel due to surface irregularities. We provided experimentally derived coefficients that supplement present theoretical concepts describing melting in forecast models. In this way, our study contributes to the improvement of current weather forecasts.
The Evolution of Asymmetries in the Tropical Cyclone Boundary Layer Wind Field during Landfall
Authors: Hlywiak James , Nolan David S. 
Published: January 2022

Abstract
The evolution of the tropical cyclone boundary layer (TCBL) wind field before landfall is examined in this study. As noted in previous studies, a typical TCBL wind structure over the ocean features a supergradient boundary layer jet to the left of motion and Earth-relative maximum winds to the right. However, the detailed response of the wind field to frictional convergence at the coastline is less well known. Here, idealized numerical simulations reveal an increase in the offshore radial and vertical velocities beginning once the TC is roughly 200 km offshore. This increase in the radial velocity is attributed to the sudden decrease in frictional stress once the highly agradient flow crosses the offshore coastline. Enhanced advection of angular momentum by the secondary circulation forces a strengthening of the supergradient jet near the top of the TCBL. Sensitivity experiments reveal that the coastal roughness discontinuity dominates the friction asymmetry due to motion. Additionally, increasing the inland roughness through increasing the aerodynamic roughness length enhances the observed asymmetries. Last, a brief analysis of in situ surface wind data collected during the landfall of three Gulf of Mexico hurricanes is provided and compared to the idealized simulations. Despite the limited in situ data, the observations generally support the simulations. The results here imply that assumptions about the TCBL wind field based on observations from over horizontally homogeneous surface types—which have been well documented by previous studies—are inappropriate for use near strong frictional heterogeneity.
Clinical and Socioeconomic Factors that Predict Non-completion of Adjuvant Chemotherapy for Colorectal Cancer in a Rural Cancer Center
Authors: Knotts Chelsea , Van Horn Alexandra , Orminski Krysta , Thompson Stephanie , Minor Jacob , Elmore Michael , Richmond Bryan K. 
Published: January 2022

Background Previous literature demonstrates correlations between comorbidities and failure to complete adjuvant chemotherapy. Frailty and socioeconomic disparities have also been implicated in affecting cancer treatment outcomes. This study examines the effect of demographics, comorbidities, frailty, and socioeconomic status on chemotherapy completion rates in colorectal cancer patients. Methods This was an observational case-control study using retrospective data from Stage II and III colorectal cancer patients offered chemotherapy between January 01, 2013 and January 01, 2018. Data was obtained using the cancer registry, supplemented with chart review. Patients were divided based on treatment completion and compared with respect to comorbidities, age, Eastern Cooperative Oncology Group (ECOG) score, and insurance status using univariate and multivariate analyses. Results 228 patients were identified: 53 Stage II and 175 Stage III. Of these, 24.5% of Stage II and 30.3% of Stage III patients did not complete chemotherapy. Neither ECOG status nor any comorbidity predicted failure to complete treatment. Those failing to complete chemotherapy were older (64.4 vs 60.8 years, P = .043). Additionally, those with public assistance or self-pay were less likely to complete chemotherapy than those with private insurance ( P = .049). Both factors (older age/insurance status) remained significant on multivariate analysis (increasing age at diagnosis: OR 1.03, P =.034; public insurance: OR 1.84, P = .07; and self-pay status: OR 4.49, P = .03). Conclusions No comorbidity was associated with failure to complete therapy, nor was frailty, as assessed by ECOG score. Though frailty was not significant, increasing age was, possibly reflecting negative attitudes toward chemotherapy in older populations. Insurance status also predicted failure to complete treatment, suggesting disparities in access to treatment, affected by socioeconomic factors.
Prolonged Surgical Interval Following Chemotherapy in a Patient With Idiopathic Subglottic Stenosis (iSGS): Case Report and Brief Review of Literature
Authors: Ospino Rafael , Berges Alexandra , Chen Lena W. , Lina Ioan , Hillel Alexander T. 
Published: January 2022

Objective: To report a case of a patient with idiopathic subglottic stenosis (iSGS) who no longer required surgical intervention for her disease following a chemotherapy regimen of carboplatin and doxorubicin for ovarian cancer. A brief review of the literature and discussion on the possible mechanism of action of chemotherapy agents affecting fibrosis is included. Methods: Case report and review of literature. Results: A 71-year-old Caucasian woman with iSGS was managed with serial endoscopic excision and dilation (n = 5) from 2013 to 2017 with an average dilation interval of 12.3 months. After a course of doxorubicin and carboplatin to treat her ovarian cancer, we observed that her airway stenosis surprisingly stabilized, and has no longer required a surgical dilation for 45 months, which signifies an increase of 33 months when compared to her averaged dilation interval (12.3 months) prior to her second course of chemotherapy. Conclusion: We present an iSGS patient whose fibrosis was arrested following carboplatin/doxorubicin treatment. While a single case, a possible mechanism is carboplatin/doxorubicin’s inhibition of pathologic CD4 lymphocytes that propagate laryngotracheal fibrosis. Further investigation of like mechanisms may allow for translation of local agents with inhibitory effects on CD4+ cells and/or fibroblasts as a novel therapy for airway fibrosis.
Quantitative Hydrogen Chloride Detection in Combustion Environments Using Tunable Diode Laser Absorption Spectroscopy with Comprehensive Investigation of Hot Water Interference
Authors: Weng Wubin , Larsson Jim , Bood Joakim , Aldén Marcus , Li Zhongshan 
Published: January 2022

Hydrogen chloride (HCl) monitoring during combustion/gasification of biomass fuels and municipal solid waste, such as polyvinyl chloride (PVC) and food residues, is demanded to avoid the adverse effect of HCl to furnace operation and to improve the quality of the gas products. Infrared tunable diode laser absorption spectroscopy (IR-TDLAS) is a feasible nonintrusive in-situ method for HCl measurements in harsh environments. In the present work, the measurement was performed using the R(3) line of the ν2 vibrational band of HCl at 5739.25 cm–1 (1742.4 nm). Water vapor is ubiquitous in combustion/gasification environments, and its spectral interference is one of the most common challenges for IR-TDLAS. Spectral analysis based on the current well-known databases was found to be insufficient to achieve an accurate measurement. The lack of accurate temperature-dependent water spectra can introduce thousands parts per million (ppm) HCl overestimation. For the first time, accurate spectroscopic data of temperature-dependent water spectra near 5739.3 cm–1 were obtained based on a systematic experimental investigation of the hot water lines in a well-controlled, hot flue gas with a temperature varying from 1100 to 1950 K. With the accurate knowledge of hot water interference, the HCl TDLAS system can achieve a detection limit of about 100 ppm⋅m at around 1500 K, and simultaneously the gas temperature can be derived. The technique was applied to measure the temporally resolved HCl release and local temperature over burning PVC particles in hot flue gas at 1790 K.
The Perception of Automation Reliability and Acceptance of Automated Advice
Authors: Hutchinson Jack , Strickland Luke , Farrell Simon , Loft Shayne 
Published: January 2022

Objective Examine (1) the extent to which humans can accurately estimate automation reliability and calibrate to changes in reliability, and how this is impacted by the recent accuracy of automation; and (2) factors that impact the acceptance of automated advice, including true automation reliability, reliability perception, and the difference between an operator’s perception of automation reliability and perception of their own reliability. Background Existing evidence suggests humans can adapt to changes in automation reliability but generally underestimate reliability. Cognitive science indicates that humans heavily weight evidence from more recent experiences. Method Participants monitored the behavior of maritime vessels (contacts) in order to classify them, and then received advice from automation regarding classification. Participants were assigned to either an initially high (90%) or low (60%) automation reliability condition. After some time, reliability switched to 75% in both conditions. Results Participants initially underestimated automation reliability. After the change in true reliability, estimates in both conditions moved towards the common true reliability, but did not reach it. There were recency effects, with lower future reliability estimates immediately following incorrect automation advice. With lower initial reliability, automation acceptance rates tracked true reliability more closely than perceived reliability. A positive difference between participant assessments of the reliability of automation and their own reliability predicted greater automation acceptance. Conclusion Humans underestimate the reliability of automation, and we have demonstrated several critical factors that impact the perception of automation reliability and automation use. Application The findings have potential implications for training and adaptive human-automation teaming.
The association between financial strain and volatility in daily relationship uncertainty: A dyadic investigation
Authors: Gajos Jamie M. , Totenhagen Casey J. , Wilmarth Melissa J. 
Published: January 2022

Prior research suggests that financial strain negatively impacts relational outcomes and that fluctuations (i.e., volatility) in daily reports of relationship aspects may be detrimental for relational outcomes. Daily relational uncertainty may also be associated with financial stressors; however, little is known about the association between financial strain and levels of daily relational uncertainty, as well as the volatility in day-to-day relational uncertainty. The current study includes both members of 100 adult different-sex couples (relationship length M = 7.0 years, SD = 7.1) who completed 14 days of daily diaries. We examined whether greater baseline financial strain is associated with higher levels of daily relational uncertainty and greater day-to-day volatility in relational uncertainty among actors and partners. Individuals who reported greater financial strain also reported higher overall levels of daily relationship uncertainty, as well as greater volatility in daily relationship uncertainty. The association between actor financial strain and volatility in daily relationship uncertainty was moderated by gender and marital status, such that financial strain was only associated with greater volatility in daily relationship uncertainty for men (but not for women) and for unmarried (but not married) individuals. Evidence for partner effects were also found, where partners’ higher levels of financial strain was associated with less volatility in actors’ daily relational uncertainty; however, this relationship was moderated by income, gender, and marital status. Individuals with lower income levels (versus high income levels) reported less volatility in their daily relationship uncertainty when their partners reported higher financial strain. Males rather than women reported lower volatility in daily relational uncertainty when their partners reported greater financial strain. In addition, unmarried rather than married individuals reported greater volatility in daily relationship uncertainty when their partners reported higher financial strain. Implications for future research and practice are discussed.
Activation of the aryl hydrocarbon receptor by clozapine induces preadipocyte differentiation and contributes to endothelial dysfunction
Authors: Fehsel K , Schwanke K , Kappel BA , Fahimi E , Meisenzahl-Lechner E , Esser C , Hemmrich K , Haarmann-Stemmann T , Kojda G , Lange-Asschenfeldt C 
Published: January 2022

Background: The superior therapeutic benefit of clozapine is often associated with metabolic disruptions as obesity, insulin resistance, tachycardia, higher blood pressure, and even hypertension. Aims: These adverse vascular/ metabolic events under clozapine are similar to those caused by polycyclic aromatic hydrocarbons (PAHs), and clozapine shows structural similarity to well-known ligands of the aryl hydrocarbon receptor (AhR). Therefore, we speculated that the side effects caused by clozapine might rely on AhR signaling. Methods: We examined clozapine-induced AhR activation by luciferase reporter assays in hepatoma HepG2 cells and we proved upregulation of the prototypical AhR target gene Cyp1A1 by realtime-PCR (RT-PCR) analysis and enzyme activity. Next we studied the physiological role of AhR in clozapine’s effects on human preadipocyte differentiation and on vasodilatation by myography in wild-type and AhR-/- mice. Results: In contrast to other antipsychotic drugs (APDs), clozapine triggered AhR activation and Cyp1A1 expression in HepG2 cells and adipocytes. Clozapine induced adipogenesis via AhR signaling. After PGF2α-induced constriction of mouse aortic rings, clozapine strongly reduced the maximal vasorelaxation under acetylcholine in rings from wild-type mice, but only slightly in rings from AhR-/- mice. The reduction was also prevented by pretreatment with the AhR antagonist CH-223191. Conclusion: Identification of clozapine as a ligand for the AhR opens new perspectives to explain common clozapine therapy-associated adverse effects at the molecular level.
The effects of psilocybin on cognitive and emotional functions in healthy participants: Results from a phase 1, randomised, placebo-controlled trial involving simultaneous psilocybin administration and preparation
Authors: Rucker James J , Marwood Lindsey , Ajantaival Riikka-Liisa J , Bird Catherine , Eriksson Hans , Harrison John , Lennard-Jones Molly , Mistry Sunil , Saldarini Francesco , Stansfield Susan , Tai Sara J , Williams Sam , Weston Neil , Malievskaia Ekaterina , Young Allan H 
Published: January 2022

Background: Psilocybin, a psychoactive serotonin receptor partial agonist, has been reported to acutely reduce clinical symptoms of depressive disorders. Psilocybin’s effects on cognitive function have not been widely or systematically studied. Aim: The aim of this study was to explore the safety of simultaneous administration of psilocybin to healthy participants in the largest randomised controlled trial of psilocybin to date. Primary and secondary endpoints assessed the short- and longer-term change in cognitive functioning, as assessed by a Cambridge Neuropsychological Test Automated Battery (CANTAB) Panel, and emotional processing scales. Safety was assessed via endpoints which included cognitive function, assessed by CANTAB global composite score, and treatment-emergent adverse event (TEAE) monitoring. Methods: In this phase 1, randomised, double-blind, placebo-controlled study, healthy participants ( n = 89; mean age 36.1 years; 41 females, 48 males) were randomised to receive a single oral dose of 10 or 25 mg psilocybin, or placebo, administered simultaneously to up to six participants, with one-to-one psychological support – each participant having an assigned, dedicated therapist available throughout the session. Results: In total, 511 TEAEs were reported, with a median duration of 1.0 day; 67% of all TEAEs started and resolved on the day of administration. There were no serious TEAEs, and none led to study withdrawal. There were no clinically relevant between-group differences in CANTAB global composite score, CANTAB cognitive domain scores, or emotional processing scale scores. Conclusions: These results indicate that 10 mg and 25 mg doses of psilocybin were generally well tolerated when given to up to six participants simultaneously and did not have any detrimental short- or long-term effects on cognitive functioning or emotional processing. Clinical Trial Registration: EudraCT ( https://www.clinicaltrialsregister.eu/ ) number: 2018-000978-30.