bluuebunny/crossref_metadata_2025_split huggingface dataset:
Resultados da curetagem estendida com e sem aloenxerto ósseo para tumores de células gigantes de grau II no joelho. Um estudo comparativo retrospectivo
Authors: Sahito Badaruddin , Ali Sheikh Muhammad Ebad , Majid Bushra , Katto Muhammad Soughat , Jatoi Asif , Jahanzeb Syed 
Published: April 2022

Resumo
Objetivo Este é o primeiro estudo a estabelecer a utilidade da curetagem estendida com ou sem enxerto ósseo em tumores de células gigantes (TCGs) de grau II na articulação do joelho com o objetivo de explorar os resultados funcionais pós-operatórios.
Métodos Revisamos retrospectivamente 25 casos de TCGs de grau II de Campanacci submetidos a curetagem estendida entre janeiro de 2014 e dezembro de 2019. Os participantes foram divididos em 2 grupos: um grupo de 12 pacientes foi submetido a curetagem estendida com aloenxerto ósseo e cimento ósseo, enquanto o outro grupo, com 13 pacientes, foi submetido a curetagem estendida apenas com cimento ósseo. A qualidade de vida foi avaliada pela Pontuação Revista da Musculoskeletal Tumor Society (MTS, na sigla em inglês) e pela Pontuação da Knee Society (KS, na sigla em inglês), enquanto as taxas de recidiva e complicações foram avaliadas em cada coorte na última consulta de acompanhamento. O teste de Fisher e os testes t de duas amostras foram usados para comparação de resultados categóricos e contínuos, respectivamente
Resultados A média de idade dos pacientes foi de 28,09 (7,44) anos; 10 (40%) pacientes eram do sexo masculino e 15 (60%) pacientes eram do sexo feminino. O fêmur distal e a tíbia proximal foram acometidos em 13 (52%) e 12 (48%) dos pacientes, respectivamente. Não houve diferença significativa na pontuação revista da MTS (25,75 versus 27,41; p = 0,178), na pontuação da KS (78,67 versus 81,46; p = 0,33) e nas taxas de recidiva (0 versus 0%; p = 1) e complicações (25 versus 7,69%; p = 0,21).
Conclusões A curetagem estendida com ou sem aloenxerto ósseo tem resultados funcionais semelhantes em pacientes com TCGs de grau II no joelho, sem qualquer diferença importante na incidência de recidivas e complicações. No entanto, a conveniência cirúrgica e o custo-benefício podem favorecer a utilização apenas de cimento ósseo, enquanto a prevenção da osteoartrite em longo prazo precisa ser investigada para favorecer o enxerto ósseo.
Histological and Immunohistochemical Characteristics for Hereditary Breast Cancer Risk in a Cohort of Brazilian Women
Authors: de Freitas Renata Mendes , Guerra Maximiliano Ribeiro , Fayer Vívian Assis , Campos Angélica Atala Lombelo , Cintra Jane Rocha Duarte , Warren Joan , Ervilha Rafaela Russi , de Paula Camila Damasceno , Bustamante-Teixeira Maria Teresa 
Published: April 2022

Abstract
Objective The study aimed to characterize the clinical, histological, and immunohistochemical profile of women with invasive breast cancer, according to the risk for Hereditary Predisposition Breast and Ovarian Cancer Syndrome in a Brazilian population.
Methods This is a retrospective study performed from a hospital-based cohort of 522 women, diagnosed with breast cancer treated at an oncology referral center in the Southeast region of Brazil, between 2014 and 2016.
Results Among the 430 women diagnosed with invasive breast cancer who composed the study population, 127 (29.5%) were classified as at increased risk for hereditary predisposition to breast and ovarian cancer syndrome. There was a lower level of education in patients at increased risk (34.6%) when compared with those at usual risk (46.0%). Regarding tumor characteristics, women at increased risk had higher percentages of the disease diagnosed at an advanced stage (32.3%), and with tumors > 2cm (63.0%), with increased prevalence for both characteristics, when compared with those at usual risk. Furthermore, we found higher percentages of HG3 (43.3%) and Ki-67 ≥ 25% (64.6%) in women at increased risk, with prevalence being about twice as high in this group. The presence of triple-negative tumors was observed as 25.2% in women at increased risk and 6.0% in women at usual risk, with the prevalence of absence of biomarkers being 2.5 times higher among women in the increased risk group.
Conclusion From the clinical criteria routinely used in the diagnosis of breast cancer, the care practice of genetic counseling for patients at increased risk of hereditary breast cancer in contexts such as Brazil is still scarce.
Unraveling the Possibilities of Monoclonal Protein Migration, Identification, and Characterization in SPEP on Capillary Zone Electrophoresis
Authors: Prisi Shailata , Khurana Vatsala , Saijpaul Rajni , Verma Rashmi , Chandra Lal , Koner Bidhan Chandra 
Published: April 2022

AbstractSerum protein electrophoresis (SPEP) is a method by which proteins present in serum are separated into different fractions based on their molecular weight and electric charge. Presence of M spike, composed of monoclonal protein, on electrophoretogram is a characteristic finding that can be seen in monoclonal gammopathies like multiple myeloma. M spike is most commonly seen in the gamma region however, the M-spike can be observed in fraction other than the Y fraction as well i.e. in the beta region and rarely alpha region. Here we have enumerated few cases where M protein has been seen in fractions other than the gamma region. Thus one needs to be cautious about the variable appearance of M-spike during interpretation of SPEP as some physiological proteins if elevated can also give rise to similar spike sometimes referred as pseudo monoclonal pattern.
A Lost Bullet in the Coronary Sinus: A Cautionary Tale
Authors: Halicek Martin , Alslaim Hossam , Shukla Mrinal , Freedman Arthur M. , Bates William B. , Patel Vijay S. , Weintraub Neal L. , Winkler Michael 
Published: April 2022

AbstractWe present a case of venous bullet embolism to the right atrium following a gunshot wound (GSW) to the abdomen. A 53-year-old male presented after a GSW to the abdomen. His workup included a computed tomography (CT) scan demonstrating an aortic injury with aortocaval fistula. A radio-opaque object consistent with a bullet was visualized in the right atrium. First, this case details an important decision, choice of surgery versus an interventional approach. After repair of the aortocaval fistula, the patient underwent a planned attempt to extract the bullet through a right lateral thoracotomy approach utilizing cardiopulmonary bypass to facilitate a right atriotomy. Intraoperatively, the team was not able to localize the bullet in the right atrium despite fluoroscopic evaluation. A postoperative CT scan demonstrated that the bullet had migrated into the coronary sinus. Lastly, this case demonstrates successful positioning maneuvers to dislodge the bullet out of the heart and into the inferior vena cava, allowing for the endovascular extraction of the bullet.
Post-Brexit Europeanization: re-thinking the continuum of British policies, polity, and politics trajectories
Authors: Wolff Sarah , Piquet Agathe 
Published: April 2022

AbstractWhat is the impact of the UK’s withdrawal from the EU on British policies, polity and politics and their future trajectories? This question has been overlooked so far, as many observers have focused on the identity, cultural, and political reasons behind the Brexit vote or scrutinized closely the process of withdrawal. The de-Europeanization literature has tried to capture the new dynamics behind the impact of Brexit on the domestic scene by understanding it as a will to dismantle policies and politics previously Europeanized. On the contrary, we argue here that Brexit is not necessarily the end of UK’s engagement with the EU. This editorial and this special issue provide a more nuanced explanation and support the idea that Brexit is not putting an end to the EU’s influence over British public policies. In fact, we identify several pathways to the EU–UK relationship which can be conceptualized along a continuum from de-Europeanization to re-engagement scenarios. Building on the literature that has suggested the trajectories of disengagement and de-Europeanization, this editorial more specifically contributes to the debate by coining the concept of continued engagement and re-engagement and highlighting the need to analyse British politics, policies, and polity in relation to the EU through a variety of pathways.
Peroxisome proliferator-activated receptor delta-PPARδ agonist (L-165041) enhances bovine embryo survival and post vitrification viability
Authors: Sánchez Viafara Jesús Alfonso , de Vasconcelos Gisvani Lopes , Maculan Renata , Alves Nadja Gomes , Ferreira Marcos Brandao Dias , Sudano Mateus José , Mingoti Gisele Zoccal , Nunes Giovana Barros , de Lima Renato Ribeiro , Drumond Roberti Martins , dos Santos Raphael Nunes , Eberlin Marcos Nogueira , Negrão Fernanda , Jasmin  , Donato Mariana Aragão M. , Peixoto Christina A. , Camisão de Souza José 
Published: April 2022

The effect of L-165041 (PPARδ-agonist) on decreasing apoptosis and intracellular lipid content was assessed in fresh and vitrified–warmed in vitro-produced bovine embryos. It was hypothesised that the addition of L-165041 to the culture medium enhances development and cryopreservation. Oocytes were allocated to one of two treatments: control-standard culture medium, or L-165041 added to the medium on day 1 with no media change. Ultrastructure, cleavage, and blastocyst rates were evaluated in fresh, and in post-vitrification cultured embryos by optical and electronic microscopy. A subset of fresh embryos were fixed for TUNEL assay and for Sudan-Black-B histochemical staining. Vitrified–warmed embryos were assessed using MALDI-MS technique. Cleavage and blastocyst rates (control 49.4 ± 5.2, L-165041 51.8 ± 4.3) were not influenced by L-165041. The proportion of inner cell mass cells (ICM) was higher in fresh embryos, and the rate of total and ICM apoptosis was lower in L-165041. In warmed-embryos, total and ICM apoptosis was lower in L-165041. The overall hatching rate was higher in L-165041 (66.62 ± 2.83% vs 53.19 ± 2.90%). There was less lipid accumulation in fresh L-165041-embryos. In conclusion, the use of L-165041 is recommended to improve the viability of in vitro-derived bovine embryos.
Emergence of space and expansion of Universe
Authors: V T Hassan Basari , Krishna P B , K V Priyesh , Mathew Titus K 
Published: April 2022

Abstract
According to the principle of emergence, the expansion of the Universe can be explained as the emergence of space with the progress of cosmic time. We have analytically solved the equation of emergence proposed by Padmanabhan by assuming the Komar energy density ρ + 3P as a function of the Hubble parameter. The resulting model describes the evolution of the Universe, which proceeds towards a final de Sitter state. Model parameters have been extracted using the cosmological observational data. Further, the horizon entropy evolution of the model has been studied. The model predicts a Universe having a transition from a prior decelerated epoch to a late accelerated epoch and reasonably predicts the cosmological constant.
A stochastic gradient descent approach with partitioned-truncated singular value decomposition for large-scale inverse problems of magnetic modulus data
Authors: Li Wenbin , Wang Kangzhi , Fan Tingting 
Published: April 2022

Abstract
We propose a stochastic gradient descent approach with partitioned-truncated singular value decomposition (SVD) for large-scale inverse problems of magnetic modulus data. Motivated by a uniqueness theorem in gravity inverse problem and realizing the similarity between gravity and magnetic inverse problems, we propose to solve the level-set function modeling the volume susceptibility distribution from the nonlinear magnetic modulus data. To deal with large-scale data, we employ a mini-batch stochastic gradient descent approach with random reshuffling when solving the optimization problem of the inverse problem. We propose a stepsize rule for the stochastic gradient descent according to the Courant–Friedrichs–Lewy condition of the evolution equation. In addition, we develop a partitioned-truncated SVD algorithm for the linear part of the inverse problem in the context of stochastic gradient descent. Numerical examples illustrate the efficacy of the proposed method, which turns out to have the capability of efficiently processing large-scale measurement data for the magnetic inverse problem. A possible generalization to the inverse problem of deep neural network is discussed at the end.
Random lasers from the natural inverse photonic glass structure of Artemia eggshells
Authors: Mai Hanh Hong , Nguyen Trong Tam , Nguyen Tien Thinh , To Thanh Thuy , Nguyen Toan T , Choi Youngwoon , Choi Wonshik , Ta Van Duong 
Published: April 2022

Abstract
In this study, we demonstrate a simple approach to fabricate a high-performance random laser (RL) from the natural inverse photonic glass structure of Artemia eggshells. Herein, the three-dimensional structures of Artemia eggshells provide an ideal scattering medium with a significantly high-reflectance stopband which facilitates resonance feedback for random lasing action. By doping organic dye molecules into the Artemia eggshells, RLs are realized by optical pumping with a threshold of 79 μJ mm−2, and a quality (Q) factor of 2328. In comparison with other works on RLs from natural photonic crystals such as butterfly wings, our RLs demonstrate a significantly lower lasing threshold and a comparable Q factor. Our results indicate that the natural inverse photonic glass structure is not only served as an effective scattering medium for random lasing but also paves a novel approach in designing and fabricating bio-controlled photonic devices.
A research and development roadmap to support applications of the enhanced BIOMASS methodology
Authors: Thorne M C , Lindborg T , Brown J , Ikonen A T K , Smith G M , Smith K , Walke R 
Published: April 2022

Abstract
The International Atomic Energy Agency has coordinated an international project addressing enhancements of methods for modelling the biosphere in post-closure safety assessments of solid radioactive waste disposal. This has resulted in the enhanced BIOMASS methodology that is described elsewhere in this special issue. To a large degree, the enhancements to the BIOMASS methodology arose from experience gained in applying the original methodology, both in the context of other international projects and in assessments of existing or proposed disposal facilities for solid radioactive wastes. Here, this experience is used, together with information on the status of solid radioactive waste disposal programmes worldwide, to identify opportunities for applying the enhanced methodology and for learning from those applications. This provides a basis for identifying research and development to support application of the enhanced methodology in a variety of environmental settings. These research and development requirements include aspects related to climate change under a variety of forcing scenarios, landform development in climatic regimes ranging from cold, polar to arid, tropical, modelling of groundwater flow and contaminant transport in surface-water catchments where both fractured rock and porous sediments are present, and studies of the transport of key radioisotopes of elements central to major biogeochemical cycles, such as those of carbon, chlorine, sulphur and iodine. In addition, some remarks are made on aspects of the application of the enhanced methodology that could imply review and updating of regulations and regulatory guidance, e.g. in relation to the definition of representative persons or groups to be considered in assessments and in respect of approaches to the assessment of radiological impacts on non-human biota. Furthermore, consideration is given as to how the scientific and technical experience that has been gained and methods that have been developed in the context of solid radioactive disposal facilities could support management of contaminated sites and legacy facilities that are likely to require long-term management and stewardship.
SCARA mechanical fault identification based on WPM-SE+BPNN method
Authors: Wang Xing , Sun Laijun , Bai Hongyi , Yu Kai , Wang Baolong 
Published: April 2022

Abstract
The Selective Compliance Assembly Robot Arm (SCARA) is becoming increasingly important in industrial manufacturing and its operating condition directly determines the safe operation of production lines. However, the complex structure, the variety of mechanical faults and unstable movements of SCARA make fault identification extremely difficult. Therefore, this study proposed identification of SCARA mechanical faults based on wavelet packet multi-segment entropy (WPM-SE) + back propagation neural network (BPNN). First, the original vibration signal was decomposed into several sub-node signals by wavelet packet transform and its envelope spectrum was obtained by Hilbert transform. Then, the envelope spectrum was divided equally into multiple intervals along the time axis, and the energy of each interval was calculated. Afterwards, the feature information of the envelope spectrum was obtained from the energy of each interval, which is defined as multi-segment entropy (M-SE). Where an envelope spectrum obtains a M-SE, and the number of segmentation intervals determines the value of the M-SE. Finally, a feature vector composed of the values of the M-SE was used as the feature input data of the BPNN for mechanical fault identification in SCARA. The BPNN has been tested to achieve an average recognition accuracy of 99.67% for both single mechanical faults and multiple mechanical faults. The results show that the WPM-SE method can effectively extract the feature information of the vibration signal and achieve fast and accurate identification of mechanical faults in SCARA.
Visible light-driven photocatalytic activity of Cu2O/ZnO/Kaolinite-based composite catalyst for the degradation of organic pollutant
Authors: Fufa Paulos Asefa , Feysia Gebisa Bekele , Gultom Noto Susanto , Kuo Dong-Hau , Chen Xiaoyun , Kabtamu Daniel Manaye , Zelekew Osman Ahmed 
Published: April 2022

Abstract
Herein, we design to synthesize a novel Cu2O/ZnO/kaolinite composite catalyst by co-precipitation method. The synthesized composite catalysts were labeled as 5CZK, 10CZK, 15CZK, and 20CZK which represent 5, 10, 15, and 20% of Cu2O, respectively, on ZnO/kaolinite. The photocatalyst samples were characterized with different instruments. Moreover, the methylene blue (MB) dye was used as a target organic pollutant and the degradation was evaluated under visible light irradiation. The highest performance for the degradation of MB was achieved by 10CZK catalyst and degrades 93% within 105 min. However, ZnO (Z), Cu2O/ZnO (CZ), 5CZK, 15CZK, and 20CZK composite catalysts, degrades 28, 66, 76, 71, and 68% of MB dye, respectively. The enhanced degradation efficiency of 10CZK composites catalyst could be due to the higher adsorption properties from metakaolinite and the light-responsive properties of the Cu2O/ZnO samples under visible light. Hence, the resulting composite catalyst could be applicable for environmental remediation.
Corrigendum: Simplest bifurcation diagrams for monotone families of vector fields on a torus (2018 Nonlinearity

31 2928)
Authors: Baesens C N , Di Lallo F , MacKay R S 
Published: April 2022

Abstract
This corrigendum corrects a mistake in the paper (Baesens and MacKay 2018 Nonlinearity
31 2928–81) and the consequent conclusions. The corrected conclusions are confirmed by numerically computed bifurcation diagrams.
Plasma generation in a long, narrow, metal tube by electron beam injection
Authors: Burdovitsin V A , Bakeev I Y , Karpov K I , Oks E M 
Published: April 2022

Abstract
We present results of experimental studies of plasma generation in a long, narrow metal tube by electron beam injection into the tube and simultaneous application of a negative potential to the tube. We show that the threshold electron beam current for plasma initiation increases with decreasing pressure, decreasing tube diameter, and increasingly negative tube potential.
Vibrational excitation cross sections for non-equilibrium nitric oxide-containing plasma
Authors: Laporta V , Vialetto L , Guerra V 
Published: April 2022

Abstract
A full set of vibrationally-resolved cross sections for electron impact excitation of NO(X2Π, v) molecules is calculated from ab initio molecular dynamics, in the framework of the local-complex-potential approach. Electron–vibration energy exchanges in non-equilibrium thermodynamic conditions are studied from a state-to-state model accounting for all electron impact excitation and de-excitation processes of the nitric oxide vibration manifold, and it is shown that the calculated vibration relaxation times are in good agreement with the experimental data. The new vibrational excitation cross sections are used in a complete electron impact cross section set in order to obtain non-equilibrium electron energy distributions functions and to calculate electron transport parameters in NO. It is verified that the new cross sections bring a significant improvement between simulations and experimental swarm data, providing an additional validation of the calculations, when used within the complete set of cross sections investigated in this work.
Bistable sound insulator with an abrupt stiffness shift using magnetic-coupled dielectric elastomer actuator
Authors: Zhang Yu , Li Bo , Chang Longfei , Ma Fuyin , Zhou Xiaoling , Chen Guimin 
Published: April 2022

Abstract
Aiming at noise isolation in low frequency range, this paper presents a novel kind of membrane sound insulator featuring a bistable actuation, by combining magnets and multilayer dielectric elastomer actuator (DEA). With a critical applied voltage on DEA, it deforms and the magnets attract in terms of a bistable snapping, which leads to an abrupt stiffness shift, and consequently regulates the sound transmission loss peak frequency. An electromechanical model is established to reveal the bistable characteristics and to study the effect of voltage and structure parameters for design optimization. The sound-insulation measurement experiment verifies the tunable acoustic performance. The sound-insulation peak frequency has a maximum shift of 142, 130, and 141 Hz under voltages of 2000, 2500, and 3000 V, respectively, showing an advancing figure of merit compared with the existed acoustic metamaterial based on dielectric elastomer.
Superconducting detectors for rare event searches in experimental astroparticle physics
Authors: Kim Yong-Hamb , Lee Sang-Jun , Yang Byeongsu 
Published: April 2022

Abstract
Superconducting detectors have become an important tool in experimental astroparticle physics, which seeks to provide a fundamental understanding of the Universe. In particular, such detectors have demonstrated excellent potential in two challenging research areas involving rare event search experiments, namely, the direct detection of dark matter (DM) and the search for neutrinoless double beta decay. Here, we review the superconducting detectors that have been and are planned to be used in these two categories of experiments. We first provide brief histories of the two research areas and outline their significance and challenges in astroparticle physics. Then, we present an extensive overview of various types of superconducting detectors with a focus on sensor technologies and detector physics, which are based on calorimetric measurements and heat flow in the detector components. Finally, we introduce leading experiments and discuss their future prospects for the detection of DM and the search for neutrinoless double beta decay employing superconducting detectors.