bluuebunny/crossref_metadata_2025_split huggingface dataset:
Three-dimensional visual technique based on CT lymphography data combined with methylene blue in endoscopic sentinel lymph node biopsy for breast cancer
Authors: Wang Baiye , Ou Caifeng , Yu Jingang , Ye Jianping , Luo Yunfeng , Wang Yu , Zhang Pusheng 
Published: December 2022

Abstract
Background
The combined application of blue dye and radioisotopes is currently the primary mapping technique used for sentinel lymph node biopsy (SLNB) in breast cancer patients. However, radiocolloid techniques have not been widely adopted, especially in developing countries, given the strict restrictions on radioactive materials. Consequently, we carried out a retrospective study to evaluate the feasibility and accuracy of three-dimensional visualization technique (3DVT) based on computed tomography-lymphography (CT-LG) in endoscopic sentinel lymph node biopsy (ESLNB) for breast cancer.

Methods
From September 2018 to June 2020, 389 patients who underwent surgical treatment of breast cancer in our department were included in this study. The CT-LG data of these patients were reconstructed into digital 3D models and imported into Smart Vision Works V1.0 to locate the sentinel lymph node (SLN) and for visual simulation surgery. ESLNB and endoscopic axillary lymph node dissection were carried out based on this new technique; the accuracy and clinical value of 3DVT in ESLNB were analyzed.

Results
The reconstructed 3D models clearly displayed all the structures of breast and axilla, which favors the intraoperative detection of SLNs. The identification rate of biopsied SLNs was 100% (389/389). The accuracy, sensitivity, and false-negative rate were 93.83% (365/389), 93.43% (128/137), and 6.57% (9/137), respectively. Upper limb lymphedema occurred in one patient 3 months after surgery during the 12-month follow-up period.

Conclusions
Our 3DVT based on CT-LG data combined with methylene blue in ESLNB ensures a high identification rate of SLNs with low false-negative rates. It, therefore, has the potential to serve as a new method for SLN biopsy in breast cancer cases.
Extreme In Situ Liver Surgery Under Total Vascular Exclusion with Right Hepatic Vein and Inferior Vena Cava Grafts for an Intrahepatic Cholangiocarcinoma
Authors: Lopez-Lopez Victor , Valles Paula Gomez , Palenciano Carlos García , Canovas Sergio , Conesa Asunción López , Brusadin Roberto , Robles-Campos Ricardo 
Published: December 2022

AbstractIn this multimedia article, we demonstrate an extreme in situ liver surgery under total vascular exclusion with right hepatic vein and inferior vena cava grafts for an intrahepatic cholangiocarcinoma in a centre with experience in highly complex hepatobiliary surgery and liver transplantation. This surgical approach after neoadjuvant chemotherapy provides an opportunity for surgical salvage in patients with large tumors invading the hepatocaval confluence. This patient was considered unresectable at another hospital and referred to our unit. We performed an accurate preoperative assessment with new generation 3D modelling to plan the type of vascular reconstruction that would allow adequate hepatic venous outflow and the volume of the future liver remnant sufficient to avoid postoperative liver failure. For hemodynamic management of the patient, we performed a total hepatic vascular exclusion with veno-venous bypass without intraoperative adverse events. We used a cryopreserved carotid artery graft after previously planning the most appropriate diameter and length for right hepatic vein reconstruction. The inferior vena cava was reconstructed with gore-tex graft. During the hospital stay there were no postoperative complications. The patient is free of disease. We conclude that patients with advanced malignant liver disease should always be referred to highly specialized liver surgery centers to assess the most appropriate oncological management and the possibility of surgical resectability.
OSMANLI DÖNEMİNE AİT BİR İPEK HALININ TASARIM İLKELERİ BAKIMINDAN İNCELENMESİ
Authors: PALA YAVUZYİĞİT Zehra 
Published: December 2022

Dokumacılık Orta Asya topraklarından Anadolu’ya Türklerin göçüyle gelmiş ve günümüze kadar devamlılık sağlayan bir sanat dalı olmuştur. Dokuma kavramı, yün, ipek, pamuk vb. malzemelerle çeşitlenmiş ve sanat dünyası içinde kendine geniş bir yer edinmiştir. En eski Türk halıları günümüzde koruma altına alınmış ve çeşitli müzelerde sergilenmiştir.
18. yüzyılda Osmanlı döneminde Hereke Fabrika-i Hümayunu adında çeşitli tezgâhlardan oluşan ilk fabrika Hereke’de kurulmuştur. Bu merkezde ipek halılar dokunmuş bir süre sonra yünlü dokumalar da yapılmaya başlanmıştır. Günümüzde ise sadece Hereke’de değil başka merkezlerde de dokuma faaliyetleri sürmektedir. Araştırmada incelenen bu ipek halı Osmanlı dönemine ait bu özellikteki bir halıdır.
Çalışmada yöntem olarak nitel araştırma yöntemlerinden tarama modeli kullanılmıştır. Yapılan analizler gözlem sonucu elde edilmiştir. Nitel yöntem kapsamında Survey Tarama Modeli uygulanmıştır. Nitel verilerin işlenmesi, bulguların tanımlanması ve yorumlanmasını içeren Betimsel Analiz yaklaşımı temel alınmıştır. Araştırmanın evrenini halı sanatı içindeki ipekli dokumalar, örneklemini ise 16. yüzyıla ait incelenen Osmanlı halısı oluşturmaktadır.
Dokuma eserleri tasarım ilkelerine göre analiz eden birkaç çalışma dışında çok fazla yayın olmaması bu çalışmanın özgün ve yenilikçi olmasını sağlamaktadır. Tasarım ilkelerinin sanat eserlerinde ayrıntılı analizi sanat eserlerinin niteliğini ve tasarım değerini anlamayı kolaylaştırmaktadır. Bu durumlar çalışmanın önemini ortaya koymaktadır.
Çalışmadaki amaç, önemli bir sanat dalı olan dokumacılık içindeki halı eserin tasarım özelliklerini analiz etmek ve ortaya koymaktır. İlk olarak incelenen halının genel kompozisyon düzeni, motif kullanımı, künye bilgileri gibi özellikler paylaşılmıştır. Daha sonra tasarım ilkeleri olan denge, tekrar, ritim, zıtlık, vurgu, oran, armoni (uyum) ilkelerinin neler olduğu ayrıntılı şekilde tespit edilmiştir. Halı, bu ilkelere göre ayrıntılı analiz edilmiş ve incelenmiştir. Analizler sonucunda bir sonuca varılmış ve ulaşılan değerler ortaya konulmuştur. Araştırma kapsamında 16. yüzyıla ait incelenen eserde yapılan analizlere göre bahsi geçen tasarım ilkelerinin sistemli ve düzenli şekilde kullanıldığı tespit edilmiştir.
NEW MEDIA DAN OTORITAS KEAGAMAAN BARU: ANALISIS WACANA KONSPIRASI RAHMAT BAEQUNI (NEW MEDIA AND NEW RELIGIOUS AUTHORITIES: AN ANALYSIS ON RAHMAT BAEQUNI'S CONSPIRACY DISCOURSE)
Authors: Romario Romario 
Published: December 2022

New media has provided a wider space for religious preachers to convey their da'wah messages to the public. This raises the consequence of the increase of da'wah contents that are not properly filtered by religious authorities, including the discourse of conspiracy. In Indonesia, Rahmat Baequni is one of the controversial Muslim preachers who spreads Islamic discourse and conspiracies through YouTube and has a large number of followers (netizens). This article was compiled based on qualitative research with the aim of discussing how Rahmat Baequni built his religious authority on social media through the conspiracy discourse. The results showed that Rahmat Baequni's story telling techniques and interesting way in his delivery were able to 'attract' young people to believe and follow the messages of his lectures. On the other hand, this phenomenon has raised pros and cons among netizens regarding the validity of the conspiracy discourse initiated by Rahmat Baequni.New media telah memberikan ruang yang luas bagi para penceramah agama untuk menyampaikan pesan-pesan dakwahnya ke masyarakat. Hal ini memunculkan konsekuensi maraknya konten-konten dakwah yang tidak terfilter dengan baik oleh otoritas keagamaan, termasuk dalam hal ini adalah wacana konspirasi. Di Indonesia, Rahmat Baequni adalah salah satu penceramah Muslim kontroversial yang menyebarkan wacana Islam dan konspirasi melalui Youtube dan memiliki followers (netizen) dengan jumlah yang banyak. Artikel ini disusun berdasarkan penelitian kualitatif dengan maksud untuk membahas bagaimana Rahmat Baequni membangun otoritas keagamaannya di sosial media melalui wacana konspirasi. Hasil penelitian menunjukkan bahwa teknik story telling dan penyampaian yang menarik dari Rahmat Baequni mampu ‘menarik’ anak-anak muda untuk mempercayai dan mengikuti pesan-pesan ceramahnya tersebut. Di sisi lain, fenomena ini telah memunculkan pro dan kontra di kalangan netizen tentang keabsahan wacana konspirasi yang digagas oleh Rahmat Baequni.
Investigation on the age-hardening behavior of Al–Si–Cu–Mg cast alloys by mechanical testing, microstructural characterization, and a CNGT based precipitation model
Authors: Mao Fengxin , Weidt Moritz , Staron Peter , Busch Sebastian , Stark Andreas , Barrales-Mora Luis 
Published: December 2022

AbstractIn the present contribution, the age-hardening behavior of two commercial Al–Si–Cu–Mg alloys was studied during heat treatments at 200 °C and 240 °C. Size and volume fraction of precipitates were characterized by means of transmission electron microscopy, small-angle X-ray scattering, and small angle neutron scattering. Additionally, tensile tests were performed to evaluate the mechanical behavior. Finally, a multi-component multi-phase classical nucleation and growth theory precipitation model was developed to predict the evolution of Mg- and Cu-containing precipitates and their hardening effect. The simulations were in good agreement with experimental findings.
The Crisis of the Political. An Individual and the Cosmopolis
Authors: Kazlauskas Raimondas 
Published: December 2022

The purpose of this paper is to identify the most important problems of the crisis of the political in the first stage of Western civilization – the Greek world in the IV–II centuries BC. The crisis of the political is treated as a unique constellation of political, supra-political, and apolitical factors. The paper explores a hypothesis of how the power elite eliminates the core features of the political – tensions of consciousness and natural human hostilities – and substitutes them with management techniques that cause public apathy towards previously established democratic institutions. A theatrical model of life with an intensified function of individualizing social roles is an unavoidable result of such processes.
Head and neck radiotherapy in patients with oral rehabilitation by dental implants: analysis of implant survival
Authors: DOURADO PACHECO OLIVEIRA MARIA CANDIDA , Heeren de Oliveira Arno , Ribeiro de Campos Tarcísio Passos , Viegas da Costa Danilo , Teixeira Portela Caio Fernando 
Published: December 2022

Radiotherapy (RT) plays an important role in the treatment of patients with head and neck cancer. Clinical changes in the surrounding healthy tissue are often inevitable. The deleterious effects on the bones of the jaws have been considered a contraindication for rehabilitation with dental implants. However, in recent years, the installation of implants in irradiated patients has been consolidated as a valuable treatment option. The aim of this study was to evaluate the effect of RT on the survival of osseointegrated dental implants in patients with head and neck cancer. The applied methodology involved an electronic search in the MEDLINE database during the last five years. We identified 67 scientific documents related to the keywords: "radiotherapy", "dental implants" and "head and neck cancer", four articles were selected and reviewed, composing this analysis. It is concluded that dental implants installed in irradiated bone in the oral cavity have a high survival rate, 97.37%, provided that rigorous monitoring is instituted in RT in order to be successful in the long term. The percentage of dental implant failures tended to be higher in the group of irradiated patients.
Computer Simulations Applied to Small-Field Dosimetry in Radiotherapy
Authors: Souza Gomes da Silva Frederico , Lima de Souza Castro Andre , Cristina Ferreira Fonseca Telma 
Published: December 2022

With the advancement of radiotherapy techniques, we find some challenges in small field dosimetry that are widely used in head and neck treatments, so computer simulations with the Monte Carlo method, already well established in medical physics, are a great tool for studying small field dosimetry. The present work aims to report the validate of the geometry model used for the simulations of a 6 MV LINAC beam, in addition to estimating the TPS, PDD and PDD 20,10 curves for several regular and small fields, allowing comparisons with experimental data .
Toxicity Removal of Pharmaceuticals Mixtures through Electron Beam Irradiation
Authors: Boiani NAthalia Fonseca , Kiyoshi Tominaga Flávio , Ivone Borrely Sueli 
Published: December 2022

Contamination of the aquatic environment by pharmaceuticals is becoming a global phenomenon of growing concern. Pharmaceuticals can be only partially metabolized during therapeutic use, resulting in the excretion and release of residual fractions into sewage, unaltered or in the form of metabolites they may remain active in sewage treatment facilities for a long time. Many studies have shown that wastewater treatment plants are not designed to eliminate these compounds, as such the main source of drug residues in the aquatic environment. Due to their frequency and detection in the environment, persistence and toxicity, the most studied pharmaceutical groups are antibiotics, psychiatric drugs, hormones, analgesics and anti-inflammatory, β-blockers, and antidiabetic drugs. Advanced Oxidative Processes (AOPs) have been applied as an alternative or complement to conventional sewage treatment processes, aiming the degradation and removal of toxic pollutants. Electron beam irradiation (EBI) is considered a clean process that offers an environmentally friendly alternative to degrade pollutants in the aquatic environment. This technology has been demonstrated effective for removal of multiclass pharmaceutical residues present in wastewater by using low doses (2.5-5.0 kGy). In this present study, we focused on toxicity removal of three different tertiary mixtures of pharmaceuticals, which showed toxicity removal efficiency around 80% for the mixture of Propranolol, Fluoxetine and Diclofenac; 75% for the mixture of Propranolol, Fluoxetine and Sulfadiazine; and 30% for the mixture of Acetylsalicylic acid, Fluoxetine and Metformin.
Selection of aptamers against the Jagged-1 protein
Authors: Alves da Silva Fábio Fernando , Bernardes Emerson Soares 
Published: December 2022

The breast cancer is one of the biggest public health problems in the world, being the main female type of cancer that affects the population. The Jagged-1 protein plays an important role in the biology and development of cancer, influencing angiogenesis, growth of neoplastic cells, tumor stem cells, epithelial mesenchymal transition, metastatic processes and resistance to therapies in various types of cancer. In this project, our aim was to select an aptamer for JAG1 ligand using an aptamer library, that could be used as a radiopharmaceutical for PET / SPECT / CT diagnosis of tumors that express JAG1. Our work showed that MDA-MB-231-JAG1 cells overexpress more mRNA and JAG1 protein than control cells (MDA-MB-231-Control). We also selected aptamers with high affinity for MDA-MB-231-JAG1 cells that could be a useful tool for the development of new radiopharmaceuticals for the diagnosis and treatment of tumors that overexpress JAG1.
Characterization of the collimated output fluence , in a thermal neutron field, in terms of ambient equivalent dose H*(10,0)
Authors: Paizante Santos da Silva Larissa , Silva Fernandes Simone , Wagner de Souza Walsan , De Souza Patrão Karla Cristina 
Published: December 2022

The Brazilian Neutron Laboratory at the Institute of Radioprotection and Dosimetry (IRD) developed and built a new standard facility for thermal neutron flux, seeking to provide a new homogeneous fluence to calibrate neutron detectors and personal dosimeters. The purpose of this work is therefore to characterize the collimated output fluence, in a thermal neutron field, in terms of ambient equivalent dose H*(10,0) for calibration and irradiation of personal monitors and neutron survey meters. The neutron fluence in the system irradiation field needs to be well known for personal monitors and neutron survey meters calibrated used in nuclear reactors in addition to studies and development of new materials for neutron dosimetry. The characterization of neutron thermal energy fields at the usual calibration points is one of the recommendations of the International Organization for Standardization ISO 8529, 2001 for international intercomparison of neutron fluence measurements. The determination of the ambient equivalent dose of the new facility was estimated based on a secondary transfer standard internationally known as Long Counter and properly characterized and traced back to the Neutron Laboratory primary standards.
Comparison of 18F-FDG and 68-PSMA-11 in PET for prostate cancer diagnosis
Authors: Fulle Natalia , Sabundjian Gaianê 
Published: December 2022

Prostate cancer is the second most incident neoplasm in men, except for non-melanoma skin cancer, and has the second highest mortality rate in Brazil. Early diagnosis increases the chances of cure and enables a less aggressive treatment for the patient. Nuclear Medicine presents effective alternatives for prostate cancer diagnosis, such as Positron Emission Tomography (PET) or PET and Computed Tomography (PET/CT) imaging. The aim of this study is to compare the advantages and disadvantages of the radiopharmaceuticals 18F-FDG and 68Ga-PSMA-11 used for PET or PET/CT in the diagnosis of this type of cancer. Compared to 18F-FDG, 68Ga-PSMA-11 has some advantages such as its availability by means of generators, the independent production of a cyclotron facility and its theranostic potential. The disadvantages compared to 18F-FDG are the scalability of 18F-FDG production compared to limited generator production. Despite its favorable characteristics, the radiopharmaceutical 18F-FDG has limitations in the diagnosis of some types of tumors, such as prostate cancer. All the favorable and unfavorable aspects of these two radiopharmaceuticals are presented in this work.
Educator perspectives on the use of technology in schools in previously disadvantaged communities
Authors: Chomunorwa Silence , Mashonganyika Emely S , Marevesa Andrew 
Published: December 2022

Technology plays a crucial role in education and many other sectors of the economy. The national lockdown caused by the Covid-19 pandemic has made apparent the importance of technology in education, with schools that adopted technologies continuing with teaching and learning using remote means, while other schools had to wait for physical classes to resume. The benefits of technology can only be realized if technology is adopted and accepted by the users. Educators are the key players in the success or failure of technology in education. We used an interpretivist approach to explore educator perceptions on the use of technology in South African public schools. The Motivation-Opportunity-Ability model guided the development of our data collection instruments and data analysis. Purposive sampling was used to select a public high school in an underprivileged Cape Flats community. Participants were randomly selected from the school and focus group discussions and interviews were conducted. A survey was administered to triangulate qualitative data. Results show that educators are interested in using user-friendly and effective technology. This paper comes as part of a broad study on technology in education.
The Impact of Differential Learning Model on Motor Skills and Handball-Specific Coordination Performance in 11–13-Year-Old Beginners in Handball
Authors: ÇAKIT İsmail , ÇAMLIGÜNEY Filiz , ERDİL Güven 
Published: December 2022

Aim: Improvement of skills in handball means an increase in performance. There are two main learning methods in sport: traditional (classical) and differential learning. The aim of our study was to determine the effect of plyometric training with differential learning method on agility and handball-specific coordination skills in 11-13-year-old handball athletes who are new to the sport.
Methods: In this study, 44 male secondary school students aged 11-13 years from Istanbul and Adana provinces, who were new to sports, volunteered to take part in this study. Two groups of 22 students each were randomly selected as classical training group and differential learning group. All groups were given handball training for 4 weeks as adaptation training. The training sessions were conducted four days a week for 1.5 hours for 12 weeks. Pre-tests were applied before the training period started, and post-tests were applied at the end of 12 weeks. In the study, T-test, zigzag running, obstacle tests as motor skill agility tests; For handball coordination skills, handball slalom dribbling, wall quick pass, hand wall toss pass tests were applied.
Results: Differential learning group (T-test, zig-zag running, obstacle, handball slalom dribbling, wall quick pass, hand wall toss pass tests) were statistically significant compared to the results of the classical training group (p
UM ESTUDO SOBRE MUDANÇAS INSTITUCIONAIS E NA ESTRUTURA DE GOVERNANÇA ASSOCIADAS À IMPLANTAÇÃO DO PROTOCOLO DE HIGIENIZAÇÃO DAS MÃOS EM HOSPITAIS
Authors: Januário Eder de Carvalho , Pedroso Caldeira Marcelo , Dória Calvosa Marcello Vinicius , Bresser Matheus 
Published: December 2022

Objetivo: analisar como as mudanças institucionais advindas da implantação do protocolo de higienização das maões regulamentado pela RDC nº 36 podem impactar a estrutura de governança e os incentivos de organizaões hospitalares.
Método: foram realizados estudos de casos múltiplos em três hospitais.
Fundamentação teórica: este artigo desenvolveu um modelo conceitual a partir da literatura sobre design organizacional, práticas de incentivos e mudança institucional.
Resultados: foi proposto um framework emergente e exploratório de como as organizações gerenciam as suas práticas de incentivo em ambiente de mudança institucional.
Contribuições: foram identificados processos de adesão à mudança. Estes poderão servir de guia para agências, organizações da área da saúde no gerenciamento do protocolo de higienização das mãos e redução dos indicadores de infecções nosocomiais.
GESTÃO DE OPERAÇÕES HOSPITALARES
Authors: Nery Vieira Lara Camila , Agra Pimentel Cristiane , Souza Thiago Antonio , De Toledo Neymar Alessandro 
Published: December 2022

Este artigo tem como objetivo relatar um estudo de caso da verificação de indicadores de eficiência Operating Room Effectiviness (ORE) e Makespan em um hospital em Minas Gerais – MG. A metodologia utilizada foi a revisão bibliográfica e estudo de caso. Como resultados foram calculados e analisados os valores do ORE e Makespan das salas do hospital e sugeridas contramedidas para melhoria das operações do centro cirúrgico e análise de dados. O indicador Makespan auxiliou durante a investigação da validação dos dados tempos e perdas que definem o ORE, além de assistir na melhor visualização da disponibilidade das salas cirúrgicas e seu uso. Este artigo contribui ao trazer um estudo de caso que demonstra a utilização de indicadores para pontuar contramedidas, além de apresentar a necessidade do conhecimento sobre os indicadores para além do seu cálculo, uma vez que é necessário fundamentar os conhecimentos na cultura da organização para que as medições e consequentemente, os indicadores sejam consistentes e capazes de auxiliar na tomada de decisão rápida e precisa.
Palavras-chave: Indicadores. Gestão de Operações. Centro Cirúrgico.