bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE ORTHODOX IDEALS OF THE "SILVER AGE" OF RUSSIAN POETRY: A. BLOK'S "POEMS ABOUT RUSSIA", N. GUMILEV'S "QUIVER"
Authors: Сипкина Н. Я. 
Published: January 2022

В статье исследуются православные идеалы А. А. Блока и Н. С. Гумилёва, ярких представителей поэтического поколения конца 19 - начала 20 века, изучавших Закон Божий, в котором излагались общечеловеческие принципы мирного существования людей планеты Земля. Нагорная проповедь Иисуса Христа для поэтов - Новозаветный закон любви о путях и делах, через которые человек сможет войти в Царство Божие, то есть спасти свою душу. Для Блока и Гумилёва божественный «кодекс» совести не утратил своей актуальности: о неосуждении («Не судите, и не будете судимы; не осуждайте, и не будете осуждены»), о прощении («Прощайте, и прощены будете»), о любви к врагам («Любите врагов ваших, благословляйте проклинающих вас, благотворите ненавидящих вас и молитесь за обижающих вас и гонящих вас, да будете сынами Отца вашего Небесного»), об отношении к ближним («Во всём, как хотите, чтобы с вами поступали люди, так поступайте и вы с ними»), о силе молитвы («Просите, и дано будет вам; ищите и найдёте; стучите, и отворят вам») [Библия, 1990, с. 4 - 8] и другие заповеди.
The article examines the Orthodox ideals of A. Blok and N. Gumilyov, prominent representatives of the poetic generation of the late 19 - early 20 centuries, who studied the Law of God, which set out the universal principles of the peaceful existence of people on our planet Earth. The sermon on the mount of Jesus Christ for poets is the new Testament law of love about the ways and works through which a person can enter the Kingdom of God, that is, save his soul. For Blok and Gumilyov, the Divine "code" of conscience has not lost its relevance: about non - condemnation ("do not judge, and do not be judged; condemn not, and ye shall not be condemned"), forgiveness ("Forgive, and ye shall be forgiven"), love for enemies ("Love your enemies, bless them that curse you, do good to them that hate you, and pray for them that despitefully use you, and persecute you; that ye may be sons of your Father in Heaven"), the attitude towards the others ("In everything as want that with you people acted, so do you also to them"), about the power of prayer ("Ask, and it shall be given you; seek and you will find; knock and the door will be opened to you") and the other commandments [1, p. 4 - 8].
Efectos de la disbiosis en la cavidad oral y su relación con la enfermedad de Parkinson
Authors: Cabrales Tapia Edelyn Jael , López Jurado Santiago Andrés 
Published: January 2022

Introducción: El desequilibrio en los mediadores inflamatorios ha formado la base del vínculo propuesto entre disbiosis oral y el desarrollo y la progresión de la enfermedad de Parkinson, siendo el vínculo entre los dos la "inflamación. Objetivos: Determinar los efectos de la disbiosis en cavidad oral y su relación con la Enfermedad de Parkinson. Materiales y métodos: investigación de tipo bibliográfico documental, de enfoque cualitativo, retrospectivo en la búsqueda, de diseño descriptivo y analítico, de método deductivo. Mediante uso de análisis PICO, palabras clave y términos mesh “Parkinson’s disease and Oral Dysbiosis”, “Inflammation and Parkinson’s, se utilizaron los buscadores: Pubemed, Scielo, ELsevier. Se revisaron 1150 documentos, que por criterios de inclusión y exclusión quedaron en 68. Análisis y discusión de resultados: Varios autores sugieren que los patógenos orales están involucrados en un proceso de neuroinflamación y caída de la barrera hematocefálica, lo que provocara el inicio o progresión de la enfermedad de Parkinson según algunos estudios. Conclusión: Si bien la evidencia debería ser mayor, muchos estudios indican que los patógenos orales pueden iniciar o ser un coadyuvante para el progreso de la enfermedad de Parkinson. A su vez esta enfermedad a causa degeneración motora por lo que se ve afecta la higiene oral, además estos pacientes usan ciertos fármacos que ocasionan xerostomía, por lo cual se ven afectados con mayor frecuencia por enfermedades periodontales.
La sociedad de la sociedad
Authors: Mascareño Aldo 
Published: January 2022

Diez años después de su publicación en alemán, aparece la traducción de Die Gesellschaft der Gesellschaft, la obra final de Niklas Luhmann. Obra final en tanto ha sido la última que el sociólogo alemán logró revisar en vida (el original alemán se publicó en 1997, Luhmann murió en 1998), y en tanto es la culminación de su proyecto de treinta años: el diseño de una nueva teoría de la sociedad.
El libro ha sido traducido por el profesor mexicano Javier Torres Nafarrate, a quien debemos las versiones de las principales obras de Luhmann en español. Lo acompañó en la tarea un calificado equipo de traductores, como se advierte en los prólogos. Darío Rodríguez, quien trabajó directamente con Luhmann en los años ochenta y quien introduce buena parte de la obra en español del maestro, leyó el manuscrito completamente e introdujo importantes cambios en el sentido y concepto de algunos pasajes. Es decir, lo que llega al lector es una traducción limpia y técnicamente probada por dos de los más profundos conocedores de la obra de Niklas Luhmann en habla hispana.
Aspects of Mineral Exploration Thinking
Authors: Graybeal Frederick T. 
Published: January 2022

Editor’s note: The aim of the Geology and Mining series is to introduce early career professionals and students to various aspects of mineral exploration, development, and mining in order to share the experiences and insight of each author on the myriad of topics involved with the mineral industry and the ways in which geoscientists contribute to each.

Abstract
Successful exploration requires an understanding of ore deposit models, the experience to recognize ore guides in an outcrop, nonlinear thinking, and some intuition. Models, using porphyry Cu deposits as examples, combine magmatic and hydrothermal processes; however, process and the results of process are different. Models provide important understanding of process but are not ore guides and do not drive discoveries; models function as rules that inhibit prediscovery exploration thinking. Results of the genetic process are recorded in descriptive models that do not reflect the considerable geologic variations existing between the hundreds of known porphyry Cu deposits. Discoveries and discovery cycles are driven by nonlinear thinking about ore guides visible in outcrop, not by genetic or descriptive models. Reality in an outcrop typically departs from generalized models. Reinterpretations that lead to drilling prospects rejected by previous exploration groups is what makes many discoveries. Increasingly, field-portable instruments for mineral and chemical analyses will add efficiencies.
The most important product of early exploration work is the geologic map, defined here as a decision-making document. Mapping of ore guides in any ore-forming system invariably leads to sampling of outcrops where high grading can help geologists rig the odds in their favor. However, the objective is a highly profitable mine, not just a high-grade sample. That means the mineralization must be sufficiently continuous to build the inventory of recoverable metal required for a profitable mine, regardless of grade. High grade gets you interested, but continuity gets the mine.
The principal intangible in any discovery is intuition, often described as nothing more or less than recognition, and it invariably involves experience. Perhaps the only tangible expression of intuition is displayed by individuals or teams that are unwilling to abandon a complex prospect, a behavior often described in case histories as tenacity.
استكشاف الحاجات الارشادية لدى طلبة الحلقة الثانية وما بعد التعليم الاساسي في سلطة عمان
Authors: باسم الدحادحة  , حسين الحارثي  , علي مهدي كاظم  
Published: January 2022

هدفت الدراسة إلى استكشاف مستوى الحاجات الإرشاديَّة لدى طلبة الحلقة الثانية والتعليم ما بعد الأساسيِّ، وآبائِهم ومعلِّمِيهم، في سلطنة عمان، وفقا لعدد من المتغيِّرات؛ ولتحقيق ذلك الهدف تمَّ اختيار عيِّنة عشوائيَّة، تكونت من ( 10134) فردا، بواقع( 5371 ) طالباً وطالبة و( 3276 ) أباً و( 1487 ) معلماً، من جميع محافظات سلطنة عمان الإحدى عشرة. حيث تمَّ تطبيق مقياس الحاجات الإرشاديَّة على أفراد عيِّنة الدراسة . أظهرت النتائج أنَّ مستوى الحاجات الإرشاديَّة قد جاءت في المدى المرتفع، وأظهرت النتائج أيضا أنَّ هناك فروقًا في متوسط درجات الحاجات الإرشاديَّة، وذلك لصالح الإناث، ومحافظة كلِّ من: الوسطى، وشمال الباطنة، وظفار، ومسقط. ولصالح المعلِّمين وأولياءِ الأمور، والصفوف السابع والتاسع والثاني عش، ولصالح الآباء والمعلِّمين الذين تَقِلُّ أعمارُهم عن ( 50 ) سنة، ولصالح الطلبة الحاصلين على معدَّلات مرتفعة ( 80 )فما فوق، وأخيرا لصالح الآباء والمعلمين الحاصلين على مؤهل علميٍّ بكالوريوس أو دبلوم فما دون. ولم تظهر النتائج أيَّة فروق تتعلَّق بمتغيري صفة المعلِّم والخبرة التعليميَّة للمعلِّمين، وقد تَمَّ مناقشة النتائج ووضع التوصيات.
Creating a “Micro-Colony” Within a Protectorate: The Example of the French Concession of Tourane (Đà Nẵng), 1884–1889
Authors: Le Galloudec Sunny 
Published: January 2022

Although history ultimately favored the portuary development of SàiGòn and HảiPhòng, it was Tourane (ĐNẵng) that was the initial target of French colonial ambitions in the Indochinese peninsula. For over a century (17401858), its bay and territory had been the scene and the epicenter of Franco-British overseas imperial rivalries, a fact which actively fostered an entire set of colonial images about the site, which was quite often referred to as potential base to serve the interests of commerce and the Navy. Despite these ambitions nurtured over a long period, it was only after the conquest of Tonkin, thirty years after the Cochinchina expedition, that its territory was finally established as a concession: on 3 October 1888, the French were finally seizing juridical control of Tourane.
As a conceded territory, Tourane was essential to French colonial and imperial designs. The focal point of political and economic ambitions, it was both a gateway and a means to prepare and support the French colonial project in Indochina. A hybrid and previously unknown template, the conceded territory model designed for, and from, Tourane indeed allowed the French to implement new strategies to tighten colonial rule in Indochina.
Offering an unprecedented analysis on the creation of the French concession of Tourane at the end of the 19th century, this research examines the political context during which it was conceived, the work and conclusions given by the commission in charge of studying its borders and jurisdiction, and the steps taken by the colonial administration in order to seize definitive control of a strategic territory inside what was then left of the Đại Nam Kingdom. All in all, comparing Tourane with others treaty ports, it shows how and why its territory stood out as a micro-colony in a protectorate territory (Annam-Tonkin).
On the correlation and sensitivity of so far statistical randomness tests based on runs
Authors: Linh Hoang Dinh , Chi Do Dai , Anh Nguyen Tuan , Uyen Le Thao 
Published: January 2022

Abstract—Random numbers play a very important role in cryptography. More precisely, almost cryptographic primitives are ensured their security based on random values such as random key, nonces, salts... Therefore, the assessment of randomness according to statistical tests is really essential for measuring the security of cryptographic algorithms. In this paper, we focus on so far randomness tests based on runs in the literature. First, we have proved in detail that the expected number of gaps (or blocks) of length in a random sequence of length is . Secondly, we have evaluated correlation of some tests based on runs so far using Pearson coefficient method [5, 6] and Fail-Fail ratio one [7, 8]. Surprisingly, the Pearson coefficient method do not show any strong linear correlation of these runs-based tests but the Fail-Fail ratio do. Then, we have considered the sensitivity of these runs tests with some basic transformations. Finally, we have proposed some new runs tests based on the sensitivity results and applied evaluations to some random sources.
Tóm tắt—Số ngẫu nhiên đóng một vai trò quan trọng trong mật mã. Cụ thể, độ an toàn của hầu hết các nguyên thủy mật mã đều được đảm bảo dựa trên các giá trị ngẫu nhiên như khóa, nonce, salt… Do đó, việc đánh giá tính ngẫu nhiên dựa trên các kiểm tra thống kê là thực sự cần thiết để đo độ an toàn cho các thuật toán mật mã. Trong bài báo này, chúng tôi tập trung vào các kiểm tra ngẫu nhiên dựa vào run trong các tài liệu. Đầu tiên, chúng tôi chứng minh chi tiết rằng kỳ vọng số các gap (khối) độ dài trong một chuỗi ngẫu nhiên độ dài là . Sau đó, chúng tôi đánh giá mối tương quan của một số kiểm tra dựa vào run bằng phương pháp hệ số Pearson [5, 6] và tỷ số Fail-Fail [7, 8]. Đáng ngạc nhiên là phương pháp hệ số Pearson không cho thấy bất kỳ mối tương quan tuyến tính mạnh nào của các kiểm tra dựa vào run, trong khi đó tỷ số Fail-Fail lại chỉ ra. Tiếp theo, chúng tôi xem xét độ nhạy của các kiểm tra run này với một số phép biến đổi cơ bản. Cuối cùng, chúng tôi đề xuất một số kiểm tra run mới dựa trên các kết quả độ nhạy và đánh giá áp dụng chúng cho một số nguồn ngẫu nhiên.
David Foster Wallace croisiériste. Le méga-paquebot comme destination finale du tourisme de masse
Authors: Parenteau Olivier 
Published: January 2022

Cet article est consacré à l’essai « Un truc soi-disant super auquel on ne me reprendra pas », dans lequel David Foster Wallace rend compte de son expérience de croisiériste à bord d’un méga-paquebot. Il analyse plus particulièrement les liens que Wallace tisse entre le navire de croisière et le parc, pensé à la fois comme un lieu clos aménagé à des fins de divertissement, et comme un espace flottant mortifère où s’opère un contrôle insidieux des touristes.
Habiter et pensées nomades : Réflexions sur l’architecture des Maisons des jeunes (et intergénérationnelles) au Nunavik
Authors: Blais Myriam , Vachon Marika 
Published: January 2022

L’« habiter nomade », tel un canevas intellectuel et philosophique, préside à une expérience de participation et de recherche-création en architecture, qui visait à explorer de nouvelles approches à la programmation, la conception et la construction de Maisons des jeunes (et intergénérationnelles) dans les villages du Nunavik. De telles maisons ont été envisagées comme un lieu qui procurerait unsense of home, qui invoquerait l’identité Inuit. Afin d’examiner et d’illustrer comment l’architecture pourrait accompagner les jeunes Inuit dans la réappropriation et la mise en valeur de leur identité, tout en affirmant des traditions significatives, la recherche-création a été convoquée. Dans ce contexte, l’habiter (comme « idée de la maison ») est alors abordé comme une invitation faite à l’architecture, et aux architectes, d’offrir des moments, des lieux et des occasions qui permettront aux habitants d’être leurs propres créateurs de sens. L’ensemble de la réflexion et de la démarche participative portant sur une Maison pour les jeunes inuit est traduite en quelques projets d’architecture qui mettent en lumière diverses aspirations, opportunités et désirs d’« habiter » le Nunavik.
Understanding Nanomaterial–Liver Interactions to Facilitate the Development of Safer Nanoapplications
Authors: Li Jiulong , Chen Chunying , Xia Tian 
Published: January 2022

AbstractNanomaterials (NMs) are widely used in commercial and medical products, such as cosmetics, vaccines, and drug carriers. Exposure to NMs via various routes such as dermal, inhalation, and ingestion has been shown to gain access to the systemic circulation, resulting in the accumulation of NMs in the liver. The unique organ structures and blood flow features facilitate the liver sequestration of NMs, which may cause adverse effects in the liver. Currently, most in vivo studies are focused on NMs accumulation at the organ level and evaluation of the gross changes in liver structure and functions, however, cell‐type‐specific uptake and responses, as well as the molecular mechanisms at cellular levels leading to effects at organ levels are lagging. Herein, the authors systematically review diverse interactions of NMs with the liver, specifically on major liver cell types including Kupffer cells (KCs), liver sinusoidal endothelial cells (LSECs), hepatic stellate cells (HSCs), and hepatocytes as well as the detailed molecular mechanisms involved. In addition, the knowledge gained on nano‐liver interactions that can facilitate the development of safer nanoproducts and nanomedicine is also reviewed.
3D Microvascularized Tissue Models by Laser‐Based Cavitation Molding of Collagen
Authors: Enrico Alessandro , Voulgaris Dimitrios , Östmans Rebecca , Sundaravadivel Naveen , Moutaux Lucille , Cordier Aurélie , Niklaus Frank , Herland Anna , Stemme Göran 
Published: January 2022

Abstract3D tissue models recapitulating human physiology are important for fundamental biomedical research, and they hold promise to become a new tool in drug development. An integrated and defined microvasculature in 3D tissue models is necessary for optimal cell functions. However, conventional bioprinting only allows the fabrication of hydrogel scaffolds containing vessel‐like structures with large diameters (>100 µm) and simple geometries. Recent developments in laser photoablation enable the generation of this type of structure with higher resolution and complexity, but the photo‐thermal process can compromise cell viability and hydrogel integrity. To address these limitations, the present work reports in situ 3D patterning of collagen hydrogels by femtosecond laser irradiation to create channels and cavities with diameters ranging from 20 to 60 µm. In this process, laser irradiation of the hydrogel generates cavitation gas bubbles that rearrange the collagen fibers, thereby creating stable microchannels. Such 3D channels can be formed in cell‐ and organoid‐laden hydrogel without affecting the viability outside the lumen and can enable the formation of artificial microvasculature by the culture of endothelial cells and cell media perfusion. Thus, this method enables organs‐on‐a‐chip and 3D tissue models featuring complex microvasculature.
Visible‐Light‐Driven Isocyanide Insertion to o‐Alkenylanilines: A Route to Isoindolinone Synthesis
Authors: Dahiya Anjali , Das Bubul , Sahoo Ashish Kumar , Patel Bhisma K. 
Published: January 2022

AbstractA visible‐light‐mediated intermolecular radical insertion of isocyanides to electron‐deficient o‐alkenylanilines leading to isoindolinone is reported. Deuterium (D2O) and H2O18 labelling experiments suggest H and O incorporation in the product. The formation of an N‐centered radical (NCR) via stepwise PT/ET process was confirmed by radical trapping experiments, photoluminescence, cyclic voltammetry and DFT studies. This photo cascade methodology is overall a redox neutral process featuring metal‐free condition and broad substrate scope (32 examples). The synthesis of analogue of GABA receptor antagonist shows the practical utility of this method.magnified image
Moderated Basicity of Endohedral Amine Groups in an Octa‐Cationic Self‐Assembled Cage
Authors: Ngai Courtney , Wu Hoi‐Ting , da Camara Bryce , Williams Christopher G. , Mueller Leonard J. , Julian Ryan R. , Hooley Richard J. 
Published: January 2022

AbstractA self‐assembled FeII4L6 cage was synthesized with 12 internal amines in the cavity. The cage forms as the dodeca‐ammonium salt, despite the cage carrying an overall 8+ charge at the metal centers, extracting protons from displaced water in the reaction. Despite this, the basicity of the internal amines is lower than their counterparts in free solution. The 12 amines have a sliding scale of basicity, with a ≈6 pKa unit difference between the first and last protons to be removed. This moderation of side‐chain basicity in an active site is a hallmark of enzymatic catalysis.
Fluorescence Colour Control in Perylene‐Labeled Polymer Chains Trapped by Nanotextured Silicon
Authors: Takao Ryota , Ushiro Kenta , Kusano Hazuki , Yuyama Ken‐ichi , Shoji Tatsuya , Linklater Denver P. , Ivanova Elena , Juodkazis Saulius , Tsuboi Yasuyuki 
Published: January 2022

AbstractThe ability to modulate, tune, and control fluorescence colour has attracted much attention in photonics‐related research fields. Thus far, it has been impossible to achieve fluorescence colour control (FCC) for material with a fixed structure, size, surrounding medium, and concentration. Here, we propose a novel approach to FCC using optical tweezers. We demonstrate an optical trapping technique using nanotextured Si (black‐Si) that can efficiently trap polymer chains. By increasing the laser intensity, the local concentration of perylene‐labelled water‐soluble polymer chains increased inside the trapping potential. Accordingly, the excimer fluorescence of perylene increased while the monomer fluorescence decreased, evidenced by a fluorescence colour change from blue to orange. Using nanostructure‐assisted optical tweezing, we demonstrate control of the relative intensity ratio of fluorescence of the two fluorophores, thus showing remote and reversible FCC of the polymer assembly.
Epigenetic comparison of CHO hosts and clones reveals divergent methylation and transcription patterns across lineages
Authors: Chang Meiping , Kumar Amit , Kumar Swetha , Huhn Steven , Timp Winston , Betenbaugh Michael , Du Zhimei 
Published: January 2022

AbstractIn this study, we examined DNA methylation and transcription profiles of recombinant clones derived from two different Chinese hamster ovary hosts. We found striking epigenetic differences between the clones, with global hypomethylation in the host 1 clones that produce bispecific antibody with higher productivity and complex assembly efficiency. Whereas the methylation patterns were found mostly inherited from the host, the host 1 clones exhibited continued demethylation reflected by the hypomethylation of newly emerged differential methylation regions (DMRs) even at the clone development stage. Several interconnected biological functions and pathways including cell adhesion, regulation of ion transport, and cholesterol biosynthesis were significantly altered between the clones at the RNA expression level and contained DMR in the promoter and/or gene‐body of the transcripts, suggesting epigenetic regulation. Indeed, expression changes of epigenetic regulators were observed including writers (Dnmt1, Setdb1), readers (Mecp2), and erasers (Tet3, Kdm3a, Kdm1b/5c) involved in CpG methylation, histone methylation, and heterochromatin maintenance. In addition, we identified putative transcription factors that may be readers or effectors of the epigenetic regulation in these clones. By combining transcriptomics with DNA methylation data, we identified potential processes and factors that may contribute to the variability in cell physiology between different production hosts.