bluuebunny/crossref_metadata_2025_split huggingface dataset:
In vivo evaluation of topical ascorbic acid application on skin aging by 50 MHz ultrasound
Authors: Vergilio Mariane Massufero , Aiello Laura Moretti , Furlan Andreza Sonego , Caritá Amanda Costa , Azevedo Jaqueline Rezende , Bolzinger Marie‐Alexandrine , Chevalier Yves , Leonardi Gislaine Ricci 
Published: March 2022

AbstractIntroductionAscorbic acid (AA) is a powerful antioxidant capable of acting significantly both in the prevention and treatment of the skin aging process. One way to assess the in vivo efficacy of anti‐aging treatments is by using the high‐frequency ultrasound (HFUS) skin image analysis technique, a non‐invasive approach that allows for a new level of evaluating the effectiveness of dermatological and cosmetic products. The aim of the present study was to assess the performance of a topical emulsion of liquid crystalline structures containing AA using the 50 MHz HFUS skin image analysis method.MethodsTwenty‐five healthy female participants between 35 and 60 years were included, all of whom randomly applied a placebo formulation and an AA‐containing formulation to each forearm, once a day, for 30 days. HFUS measurements were performed before using the products (T0), 2 h later (T2h), and after 30 days of use (T30d). The analyzed parameters included total skin, dermal, and epidermal echogenicity; variation and mean thickness of total skin, the epidermis and dermis; and surface roughness. Statistical analyses were performed using the Friedman test, followed by Dunn's test for comparisons of multiple means (α = 0.05).ResultsA significant increase in total skin and dermal echogenicity was observed after topical AA application.ConclusionOur findings suggest that collagen synthesis significantly increased after topical therapy with AA, which was responsible for the increment in dermal echogenicity. This study showed, through the HFUS technique, that the topical use of AA promoted dermal redensification after 30 days of application.
Efficacy of injecting hybrid cooperative complexes of hyaluronic acid for the treatment of vulvar lichen sclerosus: A preliminary study
Authors: Tedesco Marinella , Garelli Valentina , Elia Fulvia , Sperati Francesca , Biondi F. , Mosiello L. , Morrone Aldo , Migliano Emilia 
Published: March 2022

AbstractBackgroundLichen sclerosus is a chronic relapsing inflammatory skin disease, which involves most commonly the anogenital region. The gold standard in treatment is ultra‐potent topical steroids (clobetasol propionate): it aims at controlling the symptoms, stopping further scarring and distortion, and reducing the risk of cancer.ObjectivesThe aim of this preliminary study is to evaluate the efficacy of injecting Hybrid Cooperative Complexes of Hyaluronic Acid (HCC) for the treatment of vulvar lichen sclerosus (VLS).MethodsTwenty female adult patients (range: 21–78 years), aged over 18, with histopathological diagnosis of lichen sclerosus and good general conditions were enrolled. Patients underwent HCC infiltration every month, for 3 times. Patients were evaluated at baseline (T0) and after one (T1) and six months (T2) after treatment. During every visit, each patient was studied clinically and with videothermography. Itching, burning sensation, pain, and dyspareunia were reported by patients at T0, T1, and T2. The effectiveness of the treatment on patients’ quality of life and sexual function was evaluated using the Dermatology Life Quality Index (DLQI) and the Female Sexual Function Index (FSFI) at T0 and at T2.ResultsThe results of this preliminary study are very promising, in fact, all patients had a significant reduction in most symptoms after 1 and 6 months of HCC treatment. The reduction of patients with itching (p value ≤ 0.001), pain (p value = 0.031), and burning sensation (p = 0.004) at 6 months is significant. The analysis of DLQI scores revealed a significant improvement in patients’ quality of life. At baseline, the average score of DLQI (±SD) was 5.89 ± 3.68 while at follow‐up it was 3.42 ± 2.36 (p = 0.002).ConclusionsOur preliminary study has demonstrated the validity and tolerability of HCC infiltrations in patients with VLS, and the effectiveness of HCC in reducing symptoms and, thus, to improve sexuality and patient quality of life.
Genetic dissection of false smut resistance in rice through Genome Wide Association Mapping
Authors: Doddakoppalu Govindaiah Manu , Selvaraj Ramchander , Kadirimangalam Sai Rekha , Sundararajan Aiyswaraya , Nachimuthu Vishnu Varthini , Swaminathan Manonmani , Ayyasamy Ramanathan , Natarajan Devasena , Ramasamy Saraswathi , Dharmaraj Dhivyapriya , Govindan Subashini , Kari Baghyalakshmi , Muthurajan Raveendran , Paramasivam Jeyaprakash , Sabariappan Robin 
Published: March 2022

AbstractThe present investigation was performed to identify resistance sources and to unravel the genomic regions controlling false smut resistance by genome‐wide association mapping (GWAS) in 150 diverse rice accessions. This study revealed 13 highly resistant, 9 resistant, 119 moderately resistant and 9 moderately susceptible genotypes. Correlation analysis revealed that the percentage of infected florets, percentage of infected tillers, percentage of infected plants and spikelet sterility percentage showed significant association with disease severity. GWAS was performed using GLM, GLM+Q and MLM+Q+K with 214 SSR markers and resulted in 16 significant marker–trait associations with the traits, viz., percentage of infected plants, percentage of infected tillers, percentage of infected florets and disease severity. This study resulted in two major QTLs for the percentage of infected florets in the marker RM16131 (126.9 cM) and RM44 (60.9 cM) on chromosomes 3 and 8 and these can be further used in marker‐assisted selection. Several genes were portrayed around major QTL regions and further validation is needed to identify candidate genes for false smut resistance.
First report of Colletotrichum black leaf spot on strawberry caused by Colletotrichum siamense in China
Authors: Wang Cuicui , Tang Yuhai , Qiao Ning , Zhang Dezhen , Chi Wenjuan , Liu Jie , Pan Haoqin , Li Jintang 
Published: March 2022

AbstractIn August 2020, a new fungal disease was observed on strawberry in Shandong Province, which showed that small spots of grayish‐black, near round without lesions and haloes on the adaxial of strawberry leaves. The morphological features of colonies and conida on PDA medium were consistent with Colletotrichum gloeosporioides species complex. The rDNA internal transcribed spacer, calmodulin, chitin synthase, and actin from the isolates were amplified and sequenced. BLAST analysis of these four genes showed 99.24‐100.00% identity with the corresponding sequences of C. siamense in GenBank. The result of phylogenetic analysis also indicated that the pathogen was identified as C. siamense. Similar symptoms were observed on the back of strawberry leaf after spraying conidial suspensions for 3 days, and C. siamense was reisolated which confirm the Koch's rule. This is the first report of new disease of black leaf spot on strawberry caused by C. siamense.
Nutritional metabolism evaluation and image segmentation of the chicken muscle and internal organs for automatic evisceration
Authors: Chen Yan , Lu Jianjian , Feng Ke , Wan Lili , Ai Hui 
Published: March 2022

AbstractThe chicken is rich in various proteins, fatty acids, polysaccharides, trace elements, and other human essential nutrients that contribute to its high nutritional value. In this study, the expression levels of nutrition‐related genes (acetyl‐CoA acyltransferase, ACAA) of native chicken breeds were investigated. The level of GgalACAA1‐2 transcripts expression in the liver of chicken was significantly higher than that of muscle and heart. Moreover, three protein extracts were isolated from the muscle, heart, and liver tissues from the chicken, and their nutritional function was evaluated in the present study. These protein extracts had excellent DPPH and hydroxyl radical scavenging capacities and exhibited significant superoxide anion scavenging ability. Moreover, the protein extracts of muscle tissue showed an important mouse splenocyte proliferation activity and could be used as an immunomodulator of natural origin. In addition, this report presented an automatic visual inspection of chicken viscera using the active contour algorithms and the image processing method for eviscerating by the parallel robot. The recognition and positioning rate of chicken viscera obtained by the proposed method could reach 96.45%. These methods provided basic data for automated poultry slaughter and segmentation, avoiding unnecessary health risks by a pathogenic microorganism, such as avian influenza, Newcastle disease virus, and coronavirus. Moreover, the internal organs of the chicken could be fully harvested by the image segmentation of automatic evisceration, which also facilitated the processing value of these internal organs as by‐products of poultry.
Incidental Vocabulary Learning From Bilingual Subtitled Viewing: An Eye‐Tracking Study
Authors: Wang Andi , Pellicer‐Sánchez Ana 
Published: March 2022

AbstractThis study examined the effectiveness of bilingual subtitles relative to captions, subtitles, and no subtitles for incidental vocabulary learning. Learners’ processing of novel words in the subtitles and its relationship to learning gains were also explored. While their eye movements were recorded, 112 intermediate to advanced Chinese learners of English watched a documentary in one of 4 conditions: bilingual subtitles, captions, L1 subtitles, and no subtitles. Vocabulary pretests and posttests assessed the participants’ knowledge of the target vocabulary for form recognition, meaning recall, and meaning recognition. Results suggested an advantage for bilingual subtitles over captions for meaning recognition and over L1 subtitles for meaning recall. Bilingual subtitles were less effective than captions for form recognition. Participants in the bilingual subtitles group spent more time reading the Chinese translations of the target items than the English target words. The amount of attention to the English target words (but not to the translations) predicted learning gains.
Analysing transboundary water governance: A global‐regional‐national water governance framework of Tonle Sap Lake
Authors: Sithirith Mak 
Published: March 2022

AbstractTransboundary water governance is multiscale and multilevel, involving different actors with diverse powers and politics at different levels and scales. Levels and scales are key governance challenges in transboundary water governance. Although there is considerable literature on scale and level, there is very little on how to operationalize it in a transboundary river basin context. Accordingly, the present study analyses how scale and level complicate transboundary water governance, using a literature review and a case study of Tonle Sap Lake (TSL) in the Mekong River Basin to examine the level and scale affecting transboundary water governance. The present study describes the level of transboundary water governance in terms of global, regional and national implications. There are different functional spaces at each level, including agriculture, fisheries and biodiversity. Spaces are zoned into different spatial scales, based on technocratic interests, specialization, power and the politics of actors. The present study concludes that levels, spatial scales and zoning have made TSL governance more complex, leading to establishment of new institutional and legal arrangements for managing Tonle Sap, some of which compete with, conflict and overlap, meaning sound environmental management and good governance cannot be guaranteed.
Aspects of the biology and population structure of Oreochromis niloticus, Coptodon zillii and Oreochromis leucostictus tilapia in Lake Naivasha, Kenya
Authors: Yongo Edwine , Agembe Simon W. , Manyala Julius O. , Waithaka Edna 
Published: March 2022

AbstractThe Nile tilapia (Oreochromis niloticus), Redbelly tilapia (Coptodon zillii) and Blue spotted tilapia (Oreochromis leucostictus) were introduced into Lake Naivasha in the 1950s to diversify and boost the lake fisheries. These species have since been exploited in the commercial gillnet fishery. The fish stocks, however, are currently facing problems of pollution, wetland degradation and intense fishing pressures. Accordingly, the present study investigated some aspects of the biology and population structure of the three tilapiine species in light of changing lake conditions. Fish samples were collected from January to December 2019 using multifilament gillnets of 2.0‐to‐6.0‐inch mesh sizes. Immediately after their capture, the fish specimens were transported to the lab for morphometric measurements and analysis of maturity. The highest and lowest mean (±SD) total length (TL) were exhibited by O. niloticus (22.9 ± 5.2 cm) and C. zillii (14.5 ± 2.1 cm), respectively. Similarly, O. niloticus exhibited a higher mean weight (268.4 ± 18.0 g) and body depth (7.6 ± 2.5 cm), compared to the other species. O. niloticus exhibited an isometric growth pattern, while C. zillii and O. leucostictus exhibited negative allometric growth. The fish species were in good condition, with mean condition factors of 1.59 ± 0.07, 1.51 ± 0.06 and 1.23 ± 0.03 for C. zillii, O. leucostictus and O. niloticus, respectively. Furthermore, the condition factors for O. leucostictus and O. niloticus varied by size class, exhibiting a decreasing trend with increased fish size. The male:female sex ratio revealed significantly more males than females for O. niloticus (2.30:1.0) and O. leucostictus (2.36:1.0), although not for C. zillii (1.15:1.0). O. niloticus (28.0–29.0 cm TL) matured at a larger size, followed by O. leucostictus (21.0–26.0 cm TL), and C. zillii (15.0–17.0 cm TL). In comparison, values of length‐weight parameters, condition factor, sex ratio and size at first maturity of the studied fishes varied in Lake Naivasha, Victoria, Albert and George. The gillnet mesh ≤3.0″ mainly targeted small‐sized immature fish, while mesh ≥4″ targeted mature fish, particularly O. niloticus. It was concluded that gillnets with ≥4.0″ mesh could safely be applied for this fishery in Lake Naivasha, whereas the use of smaller mesh should be controlled to protect the juveniles as a means of maintaining sustainable fisheries. Furthermore, the present study also provided useful information, including size at maturity that is vital for setting mesh size for managing the lake fishery.
Impact melt rock from Jänisjärvi astrobleme: Study of the iron‐bearing phases using Raman spectroscopy, X‐ray diffraction, and Mössbauer spectroscopy
Authors: Maksimova A. A. , Zamiatina D. A. , Zamyatin D. A. , Ryanskaya A. D. , Chukin A. V. , Oshtrakh M. I. 
Published: March 2022

AbstractIron‐bearing phases in the impact melt rock (impactite) from Jänisjärvi astrobleme (Karelia, Russian Federation) were studied by optical microscopy, electron probe microanalysis, Raman spectroscopy, X‐ray diffraction, and 57Fe Mössbauer spectroscopy. The phase composition and the contents of elements were determined in the studied impactite. The Raman spectra of cordierite, chamosite, and ilmenite in the impact melt rock were measured and analyzed. The 57Fe Mössbauer spectrum of Jänisjärvi impactite demonstrated the presence of different iron microenvironments in the iron‐bearing phases in the impact melt rock, which were assigned to cordierite; the M1, M2, M3, and M4 sites in chamosite; ilmenite; and ferrihydrite.
Organic compounds in the Tarda C2 ungrouped carbonaceous chondrite: Evaluating the sources of contamination in a desert fall
Authors: Tunney Libby D. , Hill Patrick J. A. , Herd Christopher D. K. , Hilts Robert W. 
Published: March 2022

AbstractStudying organic compounds in meteorites provides important insight into the chemical processes that occurred in the early solar system. Once meteorites reach the Earth’s surface, they are subject to terrestrial organic contamination that may confound the conclusions that we draw from meteorite organic analyses. Within this study, specimens of the Tarda C2 ungrouped carbonaceous chondrite, collected within a few days of its fall on August 25, 2020, from a barren desert in Morocco, were analyzed for their organic compound contents. In addition, a sand sample from the strewn field was analyzed to confirm the sources of a handful of contaminating compounds detected in the Tarda stones. Using dichloromethane (DCM) rinses of the Tarda stone exteriors and DCM and hot water extractions of meteorite specimen powders and sand sample, and analysis of the soluble organics by gas chromatography‐mass spectrometry, we distinguish between extraterrestrial and contaminant sources for each organic compound. In this study, N‐tert‐butyldimethylsilyl‐N‐methyltrifluoroacetamide (MTBSTFA) was used to derivatize the hot water extractions to utilize its single‐step derivatization reaction ability. The compounds determined to be intrinsic to Tarda include propanoic acid, propanedioic acid, butanedioic acid, fumaric acid, methylmaleic acid, threonine, proline, glycine, urea, and cyclic octaatomic sulfur. We detected numerous terrestrial organic compounds, all of which were traced back to the meteorites’ collection area, with several being confirmed in the sand sample. Our results have implications for best practices for the collection of freshly fallen meteorites, especially carbonaceous chondrites, as well as how specimens should be handled and curated after collection.
Accumulating Semiotic Resources for Social Actions: A Case Study of L2 Icelandic in the Wild
Authors: THEODÓRSDÓTTIR GUÐRÚN , ESKILDSEN SØREN W. 
Published: March 2022

AbstractThis study investigates a second language (L2) speaker's use and learning of the Icelandic auxiliary verb ætla (pronounced /aihtla/) in the wild. This analytic focus is motivated by the L2 speaker's (Anna) own orientation to ætla as a learnable. We track Anna's use of ætla in naturally occurring social interaction over time. Anna first learns to use ætla to make requests in service encounters but this does not automatically transfer to other environments, suggesting an intricate relationship between ætla and the social action it is used to accomplish. The study illuminates (a) how this relationship between ætla expressions and the social actions they are used to accomplish develops over time, and (b) how Anna's increasingly diversified and productive varieties of ætla expressions co‐emerge with increasingly varied action accomplishment. Together, these two dimensions of L2 learning form the backbone of Anna's L2 grammar as an emergent accumulation of semiotic resources for social action. This serves as the backdrop for the article's implications for L2 education: (a) We promote the idea of exemplar‐based and interactionally situated L2 teaching, and (b) we call for increased awareness of situated and developing interactional competence and usage‐based processes and practices in the education of L2 teachers.
Combinations and Connections: Reaching Across Disciplinary Boundaries
Authors: LARSEN–FREEMAN DIANE 
Published: March 2022

AbstractThe data‐rich articles in this special issue invite readers to consider how grammar and multimodality enact social practices. In particular, they propose a reconceptualization of grammar, moving beyond an autonomous system of items and combinatorial rules to demonstrate how grammar is an embodied resource for social interaction. In this discussion, I build on this important reconceptualization of grammar in order to identify cross‐cutting themes—themes that result from combining research methodologies and connecting the research reported on here with that originating from other disciplines, especially that inspired by complex dynamic systems theory. My intention is to urge all researchers not only to pursue their own research agendas but also to build on existing common ground, in order to overcome fractionalization and to contribute to our mutual understanding.
Collaborative Mobilizations of Interbodied Communication for Cooperative Action
Authors: HELLERMANN JOHN , THORNE STEVEN L. 
Published: March 2022

AbstractDrawing on usage‐based approaches to the study of language learning—including recent research on mobility in interaction, embodied approaches to cognition and communicative action, and innovations in place‐based language learning in the wild—this article uses methods from ethnomethodological conversation analysis to investigate video recordings of 3 English language learners playing an augmented reality game that advocated for environmental stewardship. The analysis focused on 1 aspect of the game, an oral report about different green technologies, which was repeated 3 times due to technical difficulties. Analysis reveals emergent interactional dynamics that included (a) the use and creative reuse of multiword expressions, and (b) aligned interbodied cooperative practices that together supported (c) the building of a discourse structure for making oral reports that were part of the game narrative. The analysis highlights the semipermeable, collaboratively produced, and emergent nature of grammar for social action. Implications for pedagogy include (a) the consideration of structured unpredictability in language task design, and (b) a (re)conceptualization of language structure and language development as both an individual and group achievement.
Spiritual well‐being and its relationship with patient characteristics and other patient‐reported outcomes in peritoneal dialysis patients: Findings from the PDOPPS
Authors: Cheawchanwattana Areewan , Kanjanabuch Talerngsak , Puapatanakul Pongpratch , Narenpitak Surapong , Halue Guttiga , Tungsanga Kriang , Tatiyanupanwong Sajja , Lorvinitnun Pichet , Sritippayawan Suchai , Chieochanthanakij Rutchanee , Tungsanga Somkanya , Thamcharoen Natanong , Pongpirul Krit , Shen Jenny I. , Johnson David W. , Davies Simon J. , Finkelstein Fredric O. , Perl Jeffrey , Robinson Bruce ,   Thailand PDOPPS Steering Groups
Published: March 2022

AbstractBackgroundSpiritual well‐being (SWB), an individual's understanding of the meaning and purpose of life, may help patients with chronic or terminal illnesses cope with their diseases. This study aimed to assess SWB in patients on peritoneal dialysis (PD), as well as its relationship with patient characteristics and patient‐reported outcomes (PRO).MethodsThe data were obtained from questionnaires that formed part of the PD Outcomes and Practice Patterns Study (PDOPPS). Measures used in this study were SWB scores derived from the WHO quality of life, spirituality, religiousness and personal beliefs (WHOQOL‐SRPB) tool including 32 items from eight facets; physical (PCS) and mental component summary (MCS) scores of the 12‐Item Short‐Form Health Survey (SF‐12), Center of Epidemiologic Studies Depression Scale‐10 (CES‐D‐10) scores, burden of kidney disease scores and functional status scores.ResultsOverall, 529 out of 848 participants (62%) completely responded to the questionnaires and were included in the analysis. Over two‐thirds of PD patients (70%) had moderate or higher SWB scores. The SWB scores were significantly lower in patients with age >65 years and unemployed status. SWB scores positively correlated with higher PCS, MCS, burden of kidney disease scores and functional status scores, while negatively correlated with depression scores by CES‐D‐10 scale. Patients who reported significant depressive symptoms (CES‐D‐10 score ≥ 10) had significantly lower SWB scores.ConclusionBetter SWB was significantly associated with better health‐related QOL (HRQOL) and the absence of depressive symptoms. SWB may be an essential consideration in the delivery of high‐quality PD.