bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the correlation between depression and physical activity among older persons with osteoporosis: A cross-sectional study
Authors: Shi Linjun , Zhou Xiaoping , Gao Yueshan , Li Xia , Fang Ronghua , Deng Xuexue 
Published: August 2022

Abstract
Background
Osteoporosis is a common chronic disease in older persons. Physical activity can prevent chronic diseases, as well as many diseases associated with aging. Older persons often suffer from depression and other psychological problems. However, there are few studies on the correlation between depression and physical activity in older persons with osteoporosis in China.
Methods
This cross-sectional study was conducted from June 1, to December 28, 2021. A total of 207 subjects who met the inclusion and exclusion criteria were selected from the outpatient department of West China Hospital and evaluated using a self-designed demographic data questionnaire, the Self-rating Depression Scale (SDS), and the Physical Activity Scale for the Elderly (PASE). Multivariate linear regression was performed to analyze the factors affecting physical activity, and multivariate logistic regression analysis was performed to analyze the factors affecting depression. Spearman’s correlation was used to analyze the correlation between physical activity and depression in older persons with osteoporosis.
Results
A total of 173 valid questionnaires were statistically analyzed. A total of 122 (70.5%) were depressed. The median depression score was 62.5 (24.38), and the median PASE score was 69 (122). Multivariate logistic regression model results showed that physical activity and pain were the main risk factors for depression in older persons with osteoporosis (P < 0.05). Multivariate linear regression model results showed that gender, participation in social activities, activities of daily living status (ADLs), and depression were the main risk factors for physical activity in older persons with osteoporosis (P < 0.05). The results of the correlation analysis showed that physical activity was negatively correlated with depression (R = -0.510, P = 0.000).
Conclusions
We found that physical activity was negatively correlated with depression in older persons with osteoporosis in China. The lower the physical activity scores are, the higher the depression scores. This means that the less physical activity there is, the more serious the depression status. and depression status may reduce physical activity in older persons with osteoporosis. In order to better manage older persons with osteoporosis, medical staff should pay more attention to their physical activity, depression, and influencing factors.
The morphological features of the penile raphe and its clinical application in the circumcision using the disposable circumcision suture device
Authors: Liu Guang-Ming , Xu Zi-Qiang 
Published: August 2022

Abstract
OBJECTIVESto describe the morphological feature of the penile raphe, to solve the frenulum malposition based on the morphological classification of penile raphe in circumcision with the disposable circumcision suture deviceMethodsFrom November 2013 to April 2021, there were 2265 consecutive Chinese patients who underwent circumcision in our hospital. Each patient’s penile raphe morphological feature was recorded and grouped. It could be categorized four type of raphe feature : typeⅠ, the middle raphe; typeⅡ,the middle double raphe or middle band; type Ⅲ, the diamond or lozenge-shaped raphe; type Ⅳ, marked by some hyperpigmentation zone. The case of distinctive type of the penile raphe was treated with different strategy to guarantee the frenum matching. The convexity frenulum cutting site (CFCS) which could be palpated as small rounded eminence tissue at the ventral prepuce during the procedure was also used as an assisting anatomy marker. Other data recorded including operation time, type of anesthesia, intra-operative blood loss, incision healing time, complications and patient satisfactory.RESULTSAccording to the classification system there were 842 (37.2%) cases in type Ⅰ; 258 (11.4%) cases in type Ⅱ; 992 (43.8%) cases in type Ⅲ and 173 (7.6%) cases in type Ⅳ. Following the treatment principle based on the penile raphe feature, no case of notorious frenulum deviation was observed after the 16 cases of frenulum malposition recounted in the first 100 cases in our series. The overall satisfactory rate was high (2185, 93.9%).ConclusionsThe morphological classification of the penile raphe incombinating with the anatomy marker of CFCS will facilitate accurate identification of the frenulum location, better located its right position and cosmetic outcome.
Use of the advanced triple coaxial microcatheter system in superselective arterial embolisation for complex interventional cases: an initial experience with the system.
Authors: Tashi Sonam , Tan Zehao , Gogna Apoorva 
Published: August 2022

Abstract
Learning objective: To share our experience in utilizing the triple coaxial (triaxial) system in super-selective cannulation of arteries for complex embolisation procedures. Background: Percutaneous transcatheter selective embolisation is a widely performed for a myriad of oncologic (e.g. trans-arterial chemo- or radio-embolization) and non-oncologic (e.g. for embolization of bleeding and benign conditions such as uterine fibroid and benign prostate hyperplasia) purposes. The cornerstone of such embolisation procedures is to achieve super-selective cannulation of the arterial supply to the tumour/organ preventing the complication of non-target embolisation. However, the presence of tortuous and complex vascular anatomy can pose a major challenge for achieving this goal. Clinical findings/procedural details: The triaxial system utilizes 2 smaller microcatheter telescoped through each other and over a microwire within an angiographic catheter. We have adopted the use of the triaxial system due to its perceived superior torquability and trackability compared to the conventional coaxial system for cases which superselective cannulation is challenging. The triaxial system is also favourable in situations which the inner microcatheter needs to “sacrificed” after administering embolics (e.g. after administering radionuclides in radioembolization, N-butyl cyanoacrylate (NBCA) glue or dimethyl-sulfoxide (DMSO)). Through a case series with procedural details such as fluoroscopic time, contrast administered etc, we hope to illustrate the utility and efficacy of the triaxial system as well as present pitfalls in its usage. Conclusion:The triaxial system is safe for use in embolization procedures and can confer advantages over conventional co-axial system for specific situations.
Trajectories of physical function and quality of life in people with osteoarthritis: Results from a 10-year population-based cohort
Authors: Costa Daniela Sofia Albino , Lopes David G. , Cruz Eduardo B. , Henriques Ana R , Branco Jaime , Canhão Helena , Rodrigues Ana M 
Published: August 2022

Abstract
Objective
To identify long-term trajectories of physical function and health-related quality of life (HRQoL) among people with hip and/or knee osteoarthritis (HKOA) and the sociodemographic, lifestyle, and clinical factors associated with different trajectories.
Methods
Participants with HKOA from the EpiDoC study, a 10-year follow-up (2011–2021) population-based cohort, were considered. Sociodemographic, lifestyle, and clinical variables were collected at baseline in a structured interview and clinical appointment. Physical function and HRQoL were evaluated with the Health Assessment Questionnaire (HAQ) and EuroQoL, respectively, at baseline and the three follow-ups. Group-based trajectory modeling identified physical function and HRQoL trajectories. Multinomial logistic regression analyzed the associations between the covariates of interest and trajectory assignment (p < 0.05).
Results
We included 983 participants with HKOA. We identified three trajectories for each outcome: “consistently low disability” (32.0%), “slightly worsening moderate disability” (47.0%), and “consistently high disability” (21.0%) for physical function; “consistently high HRQoL” (18.3%), “consistently moderate HRQoL” (48.4%) and “consistently low HRQoL” (33.4%) for HRQoL. Age ≥ 75 years, female sex, multimorbidity, and high baseline clinical severity were associated with higher risk of assignment to poorer physical function and HRQoL trajectories. Participants with high education level and with regular physical activity had a lower risk of assignment to a poor trajectory. Unmanageable pain levels increased the risk of assignment to the “consistently moderate HRQoL” trajectory.
Conclusion
The levels of physical function and HRQoL remained stable over 10 years and highlight the importance of tailored interventions that target individuals’ modifiable risk factors associated with low physical function and HRQoL trajectories.
Protective Effects of Lactobacillus reuteri SJ-47 Exopolysaccharides on Human Skin Fibroblasts Damaged by UVA Radiation
Authors: Zhao Jingsha , Fu Hao , Zhang Yongtao , li meng , Wang Dongdong , Zhao Dan , Zhang Jiachan , Wang Changtao 
Published: August 2022

Abstract
Ultraviolet rays in sunlight can cause skin damage and premature aging. This study demonstrates that Lactobacillus reuteri SJ-47 exopolysaccharides (EPS) protect human skin fibroblasts (HSF) under UVA radiation. During the course of the experiments, we investigate the oxidative stress protection and anti-aging effects of exopolysaccharides on HSF at the biochemical, cellular and molecular levels. The results show that EPS can increase the antioxidant capacity of cells, decrease the amount of reactive oxygen species (ROS) and malondialdehyde (MDA), while improve the expression of antioxidant enzymes. At the same time, EPS can increase collagen content, which can effectively regulate the expression of genes in the senescence and apoptosis pathways, and delay skin photoaging caused by UVA irradiation.
Rising trend of man-tiger conflict at man-nature interface of Indian Sundarbans: study towards traditional understanding and challenging livelihood of Sundarbans people
Authors: Chatterjee Sisir 
Published: August 2022

Abstract

Sundarbans region has its own unique physiographical, ecological, economical and socio-cultural individuality. As a home of nearly nine million people the entire Sundarbans area has emerged as one of the poorest and malnourished region of the South-east Asia. Man-tiger conflict or tiger attacks in riverside settlements around the Sundarbans Reserve Forest in West Bengal, India are a continuous matter of concern. The principal objective of this research is to identify the reasons behind the increasing human-tiger conflict in Indian Sundarbans. Landsat-8 satellite image (path = 138, row = 45, 30m spatial resolution and eleven spectral bands) has been used to identify the high possible areas of Man-Tiger conflict within the SBR region. The survey involved 100 respondents selected from Gosaba, Kultali, Basanti and Mathurapur II CD blocks in which 85 respondents aged 50 and above were actively participated in the perceptional survey process. Result showed that major proportion of the Sundarbans people is traditionally dependent on forest resources for maintenance of their livelihood. Research identified the principal factors which have been responsible for increasing man-tiger conflict in Sundarbans such as degeneration of forests, habitat loss due to flood and sea level rise, encroachment into wildlife territories for economic activities, intrusion into human settlements for scarcity of wild pray in forest. Deulbari, Dongajora, Bhuvaneswari are the areas of human-tiger conflicts due to closeness with nearest buffer forest area. The adjoining rivers of these two villages Melmel and Gomor are highly vulnerable due to its proximity of reserve forest.
Effect of structural anisotropy on compressive creep behavior of composite rock based on digital image correlation
Authors: Tian Hongming , Shu Xiaoyun , Chen Weizhong , Tan Xianjun , Tian Yun 
Published: August 2022

Abstract
In this study, a series of uniaxial creep tests were conducted on three-dimensional printed (3DP) composite rock specimens to investigate the effects of structural anisotropy on the time-dependent behavior of the rock. Digital image correlation (DIC) was used to monitor the evolution of the full-field strain during creep tests. The Burgers model was used to analyze the anisotropic creep behavior of the composite rock. When the specimen was subjected to a low creep stress (σcr ≤ 0.55σc (failure stress of the specimen)), the creep strain was mainly induced by transient creep, and the transient creep parameter Ek exhibited increasing order-shaped anisotropy. When the specimen was subjected to a high creep stress (σcr ≥ 0.70 σc), the creep strain of the specimen was dependent on steady creep, and the steady creep parameter ηm showed U-shaped anisotropy similar to the compression strength anisotropy of the specimen. DIC observations showed that the strain concentration along the soft layer was an important factor that resulted in anisotropic creep, and the time-dependent shearing slip between the soft layer and hard material enhanced the creep anisotropy under a high creep stress. The failure modes of the specimens showed that creep failure developed first in the soft layer, and the creep process had an insignificant influence on the failure modes of the composite rock.
Fine-scale spatial variation shape fecal microbiome diversity and composition in black- tailed prairie dogs (Cynomys ludovicianus)
Authors: Neha Sufia A. , Salazar-Bravo Jorge 
Published: August 2022

Abstract

BackgroundHost associated gut microbiota are important in understanding the coevolution of host-microbe, it’s causes and consequences that may help wildlife population to adapt to its rapid climatic changes. Mammalian gut microbiota composition and diversity may be affected by a variety of factors including geographic variation, seasonal variation in diet, habitat disturbance, environmental conditions, age, and sex. However, there have been few studies that have examined how ecological and environmental factors influence gut microbiota composition in animals' natural environments. In this study, we explore how host habitat, geographical location and environmental factors affect the fecal microbiota of Cynomys ludovicianus at a small spatial scale. We collected fecal samples from five geographically distinct locations in Texas Panhandle occupying habitat classified as urban and rural areas using high throughput 16S rRNA gene amplicon sequencing. ResultsThe results showed that microbiota of fecal samples was largely dominated by phylum Bacteroidetes. Fecal microbiome diversity and composition differed significantly across sampling sites and habitats. Prairie dogs inhabiting urban areas showed reduced fecal diversity due to more homogenous environment and anthropogenic disturbance. Urban prairie dog colonies displayed greater phylogenetic variation than those in rural habitats. Differentially abundant analysis revealed that bacterial species pathogenic to humans and animals were highly abundant in urban areas which indicates that host health and fitness might be negatively affected. Random forest model identified Alistipes shahii as the important species driving the changes in fecal microbiome composition. Despite the effects of habitat and geographic location of host, we found a strong correlation with environmental factors- average maximum temperature was the best predictor of prairie dog fecal microbial diversity. ConclusionsOur findings suggest that reduction in alpha diversity in conjunction with greater dispersion in beta diversity could be indicative of declining host health in urban areas which could help determine in future conservation efforts. Moreover, several bacterial species pathogenic to humans and other animals were highly abundant in prairie dog colonies near urban areas, which may in turn adversely affect host phenotype and fitness.
Dielectric Rod Nanoantenna fed by a Planar Plasmonic Waveguide
Authors: Abadi Erfan Ahmadi Soren , Fakhte Saeed , Hosseini Seyyed Sina 
Published: August 2022

Abstract
This paper presents a tapered dielectric rod antenna excited by a folded dipole coplanar waveguide operating at terahertz frequencies. The effective refractive index of the plasmonic transmission line is obtained by two numerical methods, the Finite Element Method (FEM) and the Finite-Difference Time-Domain (FDTD), and it is used to obtain the dimensions of the gap connected to the line. We examine the antenna using two lengths of the rod. For 10 and 5 µm tapered rods, impedance bandwidths of 43.47% and 32.55%, maximum gains of 12.58 and 9.84 dB, and radiation efficiencies of more than 72.09%, 72.15% are achieved, respectively. The dielectric rod nanoantenna operates at all the optical communication band frequencies: original (O), extended (E), short (S), conventional (C), long (L), and ultra-long (U). The structure of the antenna consists of three layers. The substrate is made of silicon oxide. This paper discusses the effect of using a layer of silicon oxide to prevent direct contact between the silicon rod and the hollow T-shaped silver feedline.
Effect of a 3-month L-carnitine supplementation and resistance training program on circulating markers and bone mineral density in postmenopausal women: a randomized controlled trial
Authors: Olek Robert A. , Samborowska Emilia , Wisniewski Piotr , Wojtkiewicz Pawel , Wochna Krystian , Zielinski Jacek 
Published: August 2022

Abstract
Background: Higher circulating levels of trimethylamine N-oxide (TMAO), which is a metabolite that can be produced by the gut microbiota from L-carnitine (LC), have been associated with bone mineral density (BMD). Because, LC supplementation can improve bone density and microstructural properties in animal models, this study aimed to examine the effects of 12 weeks of LC supplementation on BMD and selected blood markers involved in bone metabolism of postmenopausal women participating in a resistance training program.Methods: Twenty-seven postmenopausal women, who had not been treated for osteoporosis, with a total T-score above -3.0 and no diet differences completed 12 weeks of resistance training. The participants’ diets were supplemented with either 1 g of LC-L-tartrate and 3 g of leucine per day (LC group) or 4 g of leucine per day as a placebo (PLA group), in a double-blind fashion. Results: After the intervention in the LC group, plasma total carnitine and serum decorin levels were higher than the corresponding preintervention values (p = 0.040 and p = 0.042, respectively). Moreover, plasma TMAO and serum SPARC levels were higher in the LC group than the corresponding preintervention values in the PLA group (p < 0.001 and p = 0.030, respectively). No changes in the BMD were observed after 3 months of the intervention.Conclusions: Administration of LC increased plasma TMAO levels and appeared to affect signaling molecules, as indicated by the increase in the resting SPARC and decorin levels, with no significant modification in the BMD.Trial registration: Retrospectively registered at the ClinicalTrials.gov (NCT05120011).
On signal recovery and blurry image reconstruction via a double parameter Hager-Zhang type iterative scheme for monotone nonlinear equations
Authors: Ahmed Kabiru , Waziri Mohammed Yusuf , Halilu Abubakar Sani 
Published: August 2022

Abstract
The one parameter scheme by Hager and Zhang (Pac. J. Optim. 2(1) 35-58(2006)) represents a group of descent iterative schemes for large-dimension minimization problems. The nonnegative parameter of the scheme determines the weight of conjuacy and descent, and by extension, the scheme's effectiveness. The scheme, however, only converges globally for the traditional strongly convex quadratic functions. Other approaches have to be applied to ensure this attribute holds for general functions. Moreover, when the parameter approaches $0$, the scheme reduces to the method by Hestenes and Stiefel \cite{kab31}, which in practical sense does not perform well due to the jamming phenomenon. By carrying out eigenvalue analysis of an adaptive two parameter Hager-Zhang type method, a new scheme is presented, which ensures global convergence for monotone functions without any condition for the type of linesearch procedure. The proposed scheme was driven by attributes exhibited by the Hager-Zhang scheme and various schemes designed with double parameters. The scheme is also applicable to non-smooth problems since it doesn't require derivatives. Using fundamental assumptions, we proved global convergence of the scheme and preliminary report of numerical experiments carried out with the scheme and some recent methods indicate it is more effective and efficient.Mathematics Subject Classification: 90C30, 90C26
Does the Ethnic Difference Affect the Pharmacokinetics of Favipiravir? A Pharmacokinetic Study in Healthy EgyptianVolunteers and Development of Level C In-vitro In-vivo Correlation
Authors: Bendas Ehab Rasmy , Rezk Mamdouh R. , Badr Kamal A. 
Published: August 2022

AbstractBackground and ObjectiveFavipiravir is an antiviral drug used to treat influenza. It is also being investigated for the treatment of a variety of other viral diseases, including SARS-CoV-2. Its pharmacokinetic profile varies depending on ethnic group. The present research examines the pharmacokinetic (Pk) features of favipiravir in healthy male Egyptian volunteers. Another goal of this research is to determine the optimum dissolution testing conditions for immediate release (IR) tablets.MethodsIn vitrodissolution testing was investigated for favipiravir tablet, Avigan®200 mg tablets, in three different pH media. The pharmacokinetic (Pk) features of favipiravir were examined in healthy male Egyptian volunteers. A newly developed and validated LC-MS/MS method was used to analyze real plasma samples of the healthy volunteers. Level Cin vitro in vivocorrelation (IVIVC) was developed to set the optimum dissolution medium to achieve accurate dissolution profile for favipiravir (IR) tablets.ResultsIn vitro dissolution results revealed significant difference among the three different dissolution media. The Pk parameters of twenty-seven human subjects showed mean value of Cpmaxof 5966.45ng/mL at median tmaxof 0.75 h with AUC0-∞equals 13325.54 ng.h/mL, showing half-life of 1.25 h. AUC0-tvs. % dissolved was used to develop level C IVIVC for favipiravir (IR) tablets.ConclusionsWhen compared to American and Caucasian volunteers, Egyptian participants had comparable Pk values, however they were considerably different from Japanese subjects. Phosphate buffer medium (pH 6.8) was found to be the optimum dissolution medium for in vitro dissolution testing for Favipiravir IR tablets.
Landslide displacement prediction based on Variational Mode Decomposition and Temporal Convolutional Network
Authors: Xu Chunying , Huang Kaibin , Wu Xinjie , Liang Ruixing , Wei Chuliang 
Published: August 2022

Abstract
The deformation process of landslides has complex nonlinear characteristics, making the accurate prediction of landslide displacement challenging. To reduce the complex displacement process and better realize the accurate and effective prediction of landslide displacement, this study proposes a hybrid model based on variational mode decomposition (VMD) and a temporal convolutional network (TCN). The VMD method was used to decompose the time series of landslide cumulative displacement data and environmental impact factors (reservoir level and rainfall) and the TCN model to make predictions. To verify the performance of the model, we predicted the cumulative landslide displacements at points ZG93 and ZG118 of the Baishuihe landslide in Zigui County, Three Gorges reservoir area. The results showed that the VMD-TCN model had higher accuracy than other models and can thus play a role in the prediction of landslide displacement and provide a reference for the early warning of landslide displacement deformation.