bluuebunny/crossref_metadata_2025_split huggingface dataset:
Individual Life-Course Socioeconomic Position and Hearing Aid Use in the Atherosclerosis Risk in Communities Study
Authors: Yi Julie S , Garcia Morales Emmanuel E , Betz Joshua F , Deal Jennifer A , Dean Lorraine T , Du Simo , Goman Adele M , Griswold Michael E , Palta Priya , Rebok George W , Reed Nicholas S , Thorpe Roland J , Lin Frank R , Nieman Carrie L 
Published: March 2022

Abstract

Background
To measure the association between individual life-course socioeconomic position (SEP) and hearing aid use, we examined childhood and adulthood socioeconomic variables collected at the Atherosclerosis Risk in Communities (ARIC) study baseline visit (1987–1989)/Life Course Socioeconomic Status study (2001–2002) and hearing aid use data collected at visit 6 (2016–2017).

Methods
ARIC is a prospective cohort study of older adults (45–64 years) recruited from 4 U.S. communities. This analysis included a subset of 2 470 participants with hearing loss at visit 6 (≥25 decibels hearing level [dB HL] better-ear) with complete hearing aid use data. Childhood SEP variables included parental education, parental occupation, and parental home ownership. Young and older adulthood SEP variables included income, education, occupation, and home ownership. Each life epoch was assigned a score ranging from 0 to 5 and then summed to calculate the individual cumulative SEP score. Multivariable-adjusted logistic regression was used to estimate the association between individual cumulative SEP and hearing aid use. Missing SEP scores were imputed for participants with incomplete socioeconomic data.

Results
Of the 2 470 participants in the analytic cohort (median [interquartile interval] age 79.9 [76.7–84.0], 1 330 [53.8%] women, 450 [18.2%] Black), 685 (27.7%) participants reported hearing aid use. Higher cumulative SEP was positively associated with hearing aid use (odds ratio [OR] = 1.09, 95% confidence interval [CI]: 1.04–1.14), and slightly stronger for childhood (OR = 1.09, 95% CI: 1.00–1.20) than older adulthood SEP score (OR = 1.06, 95% CI: 0.95–1.18).

Conclusions
In this community-based cohort of older adults with hearing loss, higher individual life-course SEP was positively associated with hearing aid use.
Social Isolation, Social Support, and Loneliness Profiles Before and After Spousal Death and the Buffering Role of Financial Resources
Authors: Freak-Poli Rosanne , Kung Claryn S J , Ryan Joanne , Shields Michael A 
Published: March 2022

Abstract

Objectives
We provide new evidence on the profiles of social isolation, social support, and loneliness before and after spousal death for older widows. We also examine the moderating effects of gender and financial resources on changes in social health before and after widowhood.

Methods
We use 19 waves of data from the Household, Income and Labour Dynamics in Australia Survey, including 749 widowed individuals and a comparison group of around 8,000 married individuals. We apply coarsened exact matching weights and control for age and time trends. Local polynomial smoothed plots show the profiles of social health from 3 years pre- to 3 years postspousal death. All analyses were stratified by gender.

Results
Spousal death was strongly associated with increased loneliness for women and men, but also an increase in interactions with friends and family not living with the bereaved. For men, financial resources (both income and asset wealth) provided some protection against loneliness. Spousal death was not associated with changes in social support or participation in community activities.

Discussion
We demonstrate that loneliness is a greater challenge of widowhood than social isolation or a lack of social support. Our findings suggest that interventions focusing only on increasing social interactions are unlikely to alleviate loneliness following spousal death. Moreover, policies that reduce the cost of formal social participation may have limited effectiveness in tackling loneliness, particularly for women. Alternative strategies, such as helping the bereaved form a new sense of identity and screening for loneliness around widowhood by health care workers, could be beneficial.
The removal of multiple reflection waves in the P receiver function through parabolic Radon transformation
Authors: Chen Yifang , Chen Jiuhui , Guo Biao , Li Shuncheng , Li Yu , Qi Shaohua , Zhao Panpan 
Published: March 2022

SUMMARY
Receiver function (RF) analysis is an indispensable method that is widely utilized to image the deep structure of the crust and upper mantle. Although the P-wave receiver function (PRF) has the advantages of a higher signal-to-noise ratio and higher resolution than S-wave receiver function, the information about P-to-S converted (Ps) phases from velocity discontinuities of the crust and upper mantle is usually obstructed by multiples from shallower crustal interfaces. Sometimes it is difficult to identify useful information about lithospheric discontinuities. In this paper, we propose a method for suppressing multiples and isolating the Ps phases of RFs. This task is accomplished by exploiting the differences in arrival times resulting from the slowness between the conversion and the multiples that occur at the same interface in the PRFs and by separating them in the Radon domain, which enables removal of crustal and sedimentary multiples. This method can effectively remove multiples and isolate the useful signals of Ps phases contained in the PRFs. We test the method on synthetic PRFs and demonstrate that crustal multiples can be effectively eliminated or suppressed and that the Ps phase of lithospheric discontinuities can be coherently traced. Next, we apply the method to real PRF data collected from the seismic station of the China Array seismic experiment (Phase II and Phase III) in the Ordos block and its adjacent area, and successfully obtain an improved common conversion point stacking image of lithospheric discontinuity structures in the depth domain, particularly for detecting the lithosphere–asthenosphere boundary.
Einsatzgruppe and Collaborator Horror: Thinking the Holocaust’s “Explicit Presence” in the Philosophy of Emmanuel Levinas
Authors: Manning Robert 
Published: March 2022

Abstract
Levinas scholars agree that his work was affected by the Holocaust and reflects a philosophical response to it. Yet Levinas only rarely mentions the Holocaust in his major philosophical writings, so how is what Levinas called “Holocaust horror” registed in his work? Here the author argues that scholarship says little about this because it has paid only scant attention to the tragedies of Levinas’s life and because it understands the Holocaust almost entirely through the lens of Auschwitz and the death camps. The author shows that Levinas’s major works show many traces of the brutal, face-to-face violence characteristic of the Holocaust’s early stage, when killing formations known as the Einsatzgruppen, along with local collaborators, murdered almost all of the Jews of Lithuania, including Levinas’s parents and brothers. Traces of this specific horror—much more than industrial killing in death camps—are registered in Levinas’s philosophy.
A novel approach of tricuspid valve repair: mitralization of tricuspid valve
Authors: Köksal Cengiz , Selçuk Emre , Kahveci Gökhan , Erdem Hasan 
Published: March 2022

Abstract

OBJECTIVES
This study presents the mid-term results of a novel tricuspid valve (TV) repair strategy defined as ‘mitralization of TV’ (resection and plication of the posterior leaflet, ring implantation, optional leaflet procedures) applied for the correction of tricuspid regurgitation (TR).

METHODS
Between 2017 and 2020, a total of 22 patients underwent concomitant TV repair using mitralization of the TV. Fourteen of the patients had functional TR (2 of them had severe tethering), 5 patients had prolapse and 3 patients had rheumatic involvement.

RESULTS
There was no in-hospital mortality. Moderate or severe TR was not observed in any patient in echocardiographic evaluations before discharge. The mean follow-up duration was 30.9 + 6.2 months. Moderate-to-severe TR-free survival was 100% in the second year and 94.7% in the third year.

CONCLUSIONS
Mitralization of the TV is a safe and effective treatment modality in terms of its mid-term results. This new technique provides an innovative perspective for the treatment of TR, especially in complex TV pathologies.
Apixaban in a porcine model of mechanical valve thrombosis in pulmonary position—a pilot study
Authors: Van Hoof Lucas , Truyers Isabelle , Van Hauwermeiren Hadewych , Nachtergaele Bram , Langenaeken Tom , Jacquemin Marc , Rega Filip , Verhamme Peter , Meuris Bart 
Published: March 2022

Abstract

OBJECTIVES
The newest mechanical valves have low thrombogenicity, making them candidates for anticoagulation with a direct oral anticoagulant. While these drugs hold great promise to replace warfarin, clinical trials have been disappointing so far. We aimed to evaluate apixaban in a porcine model of mechanical valve thrombosis with On-X® (CryoLife) aortic valves implanted in pulmonary position.

METHODS
On-X® valves were implanted in pulmonary valve position in 9 Yucatan pigs. Animals received prophylactic enoxaparin 40 mg for 1 week. Pigs in the low-dose group received 5 mg apixaban twice daily for 10 weeks. The intermediary-dose group received 5 mg twice daily for 6 weeks and then 10 mg twice daily afterwards. The high-dose group received 15 mg twice daily for 10 weeks. After sacrifice, valves were macroscopically evaluated and thrombus weight was documented.

RESULTS
The median weight of the 9 animals was 64.3 kg, range 52.5–70.9. In the low-dose group (2 animals), both valves showed manifest, chronic thrombosis with blocked hinges. In the intermediary-dose group, a normal functioning valve without thrombosis was seen in 2/4 animals. In the high-dose group (3 pigs), there was no valve thrombosis. No bleeding events occurred. In all animals, apixaban plasma levels were low compared to clinical target levels.

CONCLUSIONS
The pulmonary position seems to be an aggressive model for mechanical valve thrombosis in pigs. Apixaban has the potential to prevent valve thrombosis, even in these thrombogenic conditions. Detailed pharmacokinetic studies are needed to determine the ideal apixaban dosage for future experiments and to enable extrapolation to the clinical situation.
Measuring Political Knowledge and Not Search Proficiency in Online Surveys
Authors: DeBell Matthew 
Published: March 2022

Abstract
Most online survey questions testing political knowledge are susceptible to measurement error when participants look up the answers. This article reports five studies of methods to detect and prevent this common source of error. To detect lookups, “catch questions” are more reliable than self-reports, because many participants lie rather than admit looking up answers. Strongly worded instructions reduced lookups by about two-thirds, while the triple combination of instructions, requesting a promise not to look up answers, and adaptive feedback (asking participants who look up an answer to stop doing so) reduced the percentage of respondents looking up an answer by a further half, to 3%. For office recall knowledge items, photo-based open-ended questions eliminated lookups and had similar validity to traditional text-based versions, making them a good choice when a visual format is viable.
Gastrointestinal Microbiome Disruption and Antibiotic-Associated Diarrhea in Children Receiving Antibiotic Therapy for Community-Acquired Pneumonia
Authors: Kwon Jiye , Kong Yong , Wade Martina , Williams Derek J , Creech Clarence Buddy , Evans Scott , Walter Emmanuel B , Martin Judy M , Gerber Jeffrey S , Newland Jason G , Hofto Meghan E , Staat Mary Allen , Chambers Henry F , Fowler Vance G , Huskins W Charles , Pettigrew Melinda M 
Published: March 2022

AbstractAntibiotic-associated diarrhea (AAD) is a common side effect of antibiotics. We examined the gastrointestinal microbiota in children treated with β-lactams for community-acquired pneumonia. Data were from 66 children (n = 198 samples), aged 6–71 months, enrolled in the SCOUT-CAP trial (NCT02891915). AAD was defined as ≥1 day of diarrhea. Stool samples were collected on study days 1, 6–10, and 19–25. Samples were analyzed using 16S ribosomal RNA gene sequencing to identify associations between patient characteristics, microbiota characteristics, and AAD (yes/no). Nineteen (29%) children developed AAD. Microbiota compositional profiles differed between AAD groups (permutational multivariate analysis of variance, P &lt; .03) and across visits (P &lt; .001). Children with higher baseline relative abundances of 2 Bacteroides species were less likely to experience AAD. Higher baseline abundance of Lachnospiraceae and amino acid biosynthesis pathways were associated with AAD. Children in the AAD group experienced prolonged dysbiosis (P &lt; .05). Specific gastrointestinal microbiota profiles are associated with AAD in children.
“As Expected”: Theoretical Implications for Racialized Administrative Power as the Status Quo
Authors: Blume Grant H 
Published: March 2022

AbstractThis article posits that racialized administrative power is the status quo in the United States and results from a wicked problem broadly construed as institutional racism. Acknowledging a baseline reality of racialized administrative power in the United States allows public administration theory to more directly grapple with the institutional racism that paradoxically may seem too big and complex to empirically study yet simultaneously too important and urgent to ignore. This article offers three contributions to the development of public administration theory from this conceptual frame of racialized administrative power as the status quo. First, by conceptualizing institutional racism as a wicked problem, a case is outlined to replace an assumption of neutral administrative power with a baseline assumption of racialized administrative power in the United States. Second, the article explores two prominent areas of theory in public administration—representative bureaucracy and administrative burden—to demonstrate how a baseline assumption of racialized administrative power can reorient and expand theoretical questions and research. Third, the article discusses the epistemological implications for public administration theory and research based on an assumption that racialized administrative power is the status quo. These contributions offer a step forward in addressing the need for public administration theory to better account for the institutional racism that pervades the management and performance of public organizations in the United States.
Cytokinin oxidase/dehydrogenase family genes exhibit functional divergence and overlap in rice growth and development, especially in control of tillering
Authors: Rong Chenyu , Liu Yuexin , Chang Zhongyuan , Liu Ziyu , Ding Yanfeng , Ding Chengqiang 
Published: March 2022

Abstract
Cytokinins play key roles in plant growth and development, and hence their biosynthesis and degradation have been extensively studied. Cytokinin oxidase/dehydrogenases (CKXs) are a group of enzymes that regulate oxidative cleavage to maintain cytokinin homeostasis. In rice, 11 CKX genes have been identified to date; however, most of their functions remain unknown. In this study, we comprehensively examined the expression patterns and functions of the CKXs in rice by using CRISPR/Cas9 technology to construct mutants of all 11 genes. The results revealed that the ckx single-mutants and higher-order ckx4 ckx9 mutant lines showed functional overlaps and sub-functionalization. Notably, the ckx1 ckx2 and ckx4 ckx9 double-mutants displayed contrasting phenotypic changes in tiller number and panicle size compared to the wild-type. In addition, we identified several genes with significantly altered expression in both the ckx4 and ckx9 single-mutant and double-mutant plants. Many of the differentially expressed genes were found to be associated with auxin and cytokinin pathways, and cytokinins in the ckx4 ckx9 double-mutant were increased compared to the wild-type. Taken together, our findings provide new insights into the functions of CKX genes in rice growth and may provide the foundations for future studies aimed at improving rice yield.
The resolved chemical abundance properties within the interstellar medium of star-forming galaxies at z≈ 1.5
Authors: Gillman S , Puglisi A , Dudzevičiūtė U , Swinbank A M , Tiley A L , Harrison C M , Molina J , Sharples R M , Bower R G , Cirasuolo M , Ibar Edo , Obreschkow D 
Published: March 2022

ABSTRACT
We exploit the unprecedented depth of integral field data from the KMOS Ultra-deep Rotational Velocity Survey (KURVS) to analyse the strong (Hα) and forbidden ([N ii], [S ii]) emission line ratios in 22 main-sequence galaxies at $z\, \approx \, 1.5$. Using the [N ii]/Hα emission-line ratio, we confirm the presence of the stellar mass – gas-phase metallicity relation at this epoch, with galaxies exhibiting on average 0.13 ± 0.04 dex lower gas-phase metallicity (12 + log(O/H)M13  =  8.40 ± 0.03) for a given stellar mass (log10(M*[M⊙]  =  10.1 ± 0.1) .than local main-sequence galaxies. We determine the galaxy-integrated [S ii] doublet ratio, with a median value of [S ii]λ6716/λ6731  =  1.26 ± 0.14 equivalent to an electron density of log10(ne[cm−3])  =  1.95 ± 0.12. Utilising CANDELS HST multi-band imaging we define the pixel surface-mass and star-formation rate density in each galaxy and spatially resolve the fundamental metallicity relation at $z\, \approx \, 1.5$, finding an evolution of 0.05 ± 0.01 dex compared to the local relation. We quantify the intrinsic gas-phase metallicity gradient within the galaxies using the [N ii]/Hα calibration, finding a median annuli-based gradient of ΔZ/ΔR  =  −0.015 ± 0.005 dex kpc−1. Finally, we examine the azimuthal variations in gas-phase metallicity, which show a negative correlation with the galaxy integrated star-formation rate surface density ($r_{\rm s}\,$  =  −0.40, ps  =  0.07) but no connection to the galaxies kinematic or morphological properties nor radial variations in stellar mass surface density or star formation rate surface density. This suggests both the radial and azimuthal variations in interstellar medium properties are connected to the galaxy integrated density of recent star formation.
Homogeneous transit timing analyses of 10 exoplanet systems
Authors: Baştürk Ö , Esmer E M , Yalçınkaya S , Torun Ş , Mancini L , Helweh F , Karamanlı E , Southworth J , Aliş S , Wünsche A , Tezcan F , Aladağ Y , Aksaker N , Tunç E , Davoudi F , Fişek S , Bretton M , Evans D F , Yeşilyaprak C , Yılmaz M , Tezcan C T , Yelkenci K 
Published: March 2022

ABSTRACT
We study the transit timings of 10 exoplanets in order to investigate potential transit timing variations in them. We model their available ground-based light curves, some presented here and others taken from the literature, and homogeneously measure the mid-transit times. We statistically compare our results with published values and find that the measurement errors agree. However, in terms of recovering the possible frequencies, homogeneous sets can be found to be more useful, of which no statistically relevant example has been found for the planets in our study. We corrected the ephemeris information of all 10 planets we studied and provide these most precise light elements as references for future transit observations with space-borne and ground-based instruments. We found no evidence for secular or periodic changes in the orbital periods of the planets in our sample, including the ultra-short period WASP-103 b, whose orbit is expected to decay on an observable time-scale. Therefore, we derive the lower limits for the reduced tidal quality factors (Q$^{\prime }_{\star }$) for the host stars based on best-fitting quadratic functions to their timing data. We also present a global model of all available data for WASP-74 b, which has a Gaia parallax-based distance value ∼25 per cent larger than the published value.
Detecting the periodicity of highly irregularly sampled light curves with Gaussian processes: the case of SDSS J025214.67−002813.7
Authors: Covino Stefano , Tobar Felipe , Treves Aldo 
Published: March 2022

ABSTRACT
Based on a 20-yr-long multiband observation of its light curve, it was conjectured that the quasar SDSS J025214.67−002813.7 has a periodicity of ∼4.4 yr. These observations were acquired at a highly irregular sampling rate and feature long intervals of missing data. In this setting, the inference over the light curve’s spectral content requires, in addition to classic Fourier methods, a proper model of the probability distribution of the missing observations. In this article, we address the detection of the periodicity of a light curve from partial and irregularly sampled observations using Gaussian processes, a Bayesian non-parametric model for time series. This methodology allows us to evaluate the veracity of the claimed periodicity of the above-mentioned quasar and also to estimate its power spectral density. Our main contribution is the confirmation that considering periodic component definitely improves the modelling of the data, although being the source originally selected by a large sample of objects, the possibility that this is a chance result cannot be ruled out.
Synthetic solar cycle for active regions violating the Hale’s polarity law
Authors: Zhukova A , Khlystova A , Abramenko V , Sokoloff D 
Published: March 2022

ABSTRACTLong observational series for bipolar active regions (ARs) provide significant information about the mutual transformation of the poloidal and toroidal components of the global solar magnetic field. The direction of the toroidal field determines the polarity of leading sunspots in ARs in accordance with the Hale’s polarity law. The vast majority of bipolar ARs obey this regularity, whereas a few per cent of ARs have the opposite sense of polarity (anti-Hale ARs). However, the study of these ARs is hampered by their poor statistics. The data for five 11-yr cycles (16–18 and 23, 24) were combined here to compile a synthetic cycle of unique time length and latitudinal width. The synthetic cycle comprises data for 14838 ARs and 367 of them are the anti-Hale ARs. A specific routine to compile the synthetic cycle was demonstrated. We found that, in general, anti-Hale ARs follow the solar cycle and are spread throughout the time-latitude diagram evenly, which implies their fundamental connection with the global dynamo mechanism and the toroidal flux system. The increase in their number and percentage occurs in the second part of the cycle, which is in favour of their contribution to the polar field reversal. The excess in the anti-Hale ARs percentage at the edges of the butterfly diagram and near an oncoming solar minimum (where the toroidal field weakens) might be associated with the strengthening of the influence of turbulent convection and magnetic field fluctuations on the arising flux tubes. The evidence of the misalignment between the magnetic and heliographic equators is also found.