bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recent exposure to environmental stochasticity does not determine the resilience of natural populations
Authors: Cant James , Capdevila Pol , Beger Maria , Salguero-Gómez Roberto 
Published: April 2022

AbstractEscalating climatic and anthropogenic pressures expose ecosystems worldwide to increasingly frequent disturbances. Yet, our ability to forecast the responses of natural populations to these disturbances is impeded by a limited understanding for how exposure to stochastic environments shapes population resilience. Instead, the resilience, and vulnerability, of natural populations to ongoing global change is often presumed based on their contemporary exposure to environmental stochasticity. To test the validity of this assumption, we investigated the association between the resilience attributes (e.g., resistance and recovery) of natural animal and plant populations, and measures of local environmental stochasticity (e.g., spectral frequency and abiotic range); collating data from 2,242 populations across 369 animal, plant, and algal species. Unexpectedly, recent abiotic stochasticity regimes from the past 50 years do not predict the inherent ability of populations to resist or recover from disturbances. Instead, population resilience is strongly affected by phylogenetic relationships among species, with survival and developmental investments shaping their responses to stochastic regimes. Contrary to the classical assumption that exposure to recent environmental shifts confers a greater ability to cope with current and future global change, our findings suggest that population resilience is a consequence of evolutionary processes and/or deep-time environmental regimes.Significance statementPopulations that currently endure more variable abiotic conditions are often expected to be less vulnerable to future increases in climatic variability. However, without defining the link between abiotic variability and the capacity for populations to resist and recover following disturbances (i.e., their resilience), we cannot predict the consequences of ongoing community reassembly. Evaluating the association between measures of abiotic variability and the resilience attributes of 2,242 animal, plant, and algae populations, we discredit the assumption that contemporary exposure to more frequent environmental shifts confers a greater ability to cope with future global change. Instead, the resilience attributes of natural populations appear to have been moulded over longer-term evolutionary timeframes and are thus not a response to more recent experiences.
The “LINC” in between Δ40p53-miRNA axis in the regulation of cellular homeostasis
Authors: Pal Apala , Ghosh Pritam Kumar , Das Saumitra 
Published: April 2022

ABSTRACTPrevious research has shown that Δ40p53, the translational isoform of p53, can inhibit cell growth independently of p53 by regulating microRNAs. Here, we explored the role of Δ40p53 in regulating the long non-coding RNA-microRNA-cellular process axis, specifically focusing on LINC00176. Interestingly, LINC00176 levels were predominantly affected by the overexpression/stress-mediated induction and knockdown of Δ40p53 rather than p53 levels. Additional assays revealed that Δ40p53 transactivates LINC00176 transcriptionally and could also regulate its stability. RNA immunoprecipitation experiments revealed that LINC00176 sequesters several putative microRNA targets, which could further titrate several mRNA targets involved in different cellular processes. To understand the downstream effects of this regulation, we ectopically overexpressed and knocked down LINC00176 in HCT116 p53−/− (harboring only Δ40p53) cells, which affected their proliferation, cell viability, and expression of epithelial markers. Our results provide essential insights into the pivotal role of Δ40p53 in regulating the novel LINC00176 RNA-microRNA-mRNA axis independent of FL-p53 and in maintaining cellular homeostasis.
RNA-seq sample preparation kits strongly affect transcriptome profiles of a gas-fermenting bacterium
Authors: de Lima Lorena Azevedo , Reinmets Kristina , Nielsen Lars Keld , Marcellin Esteban , Harris Audrey , Köpke Michael , Valgepea Kaspar 
Published: April 2022

AbstractTranscriptome analysis via RNA sequencing (RNA-seq) has become a standard technique employed across various biological fields of study. This rapid adoption of the RNA-seq approach has been mediated, in part, by the development of different commercial RNA-seq library preparation kits compatible with standard next-generation sequencing (NGS) platforms. Generally, the essential steps of library preparation such as ribosomal RNA (rRNA) depletion and first-strand cDNA synthesis are tailored to a specific group of organisms (e.g. eukaryotes vs. prokaryotes) or genomic GC content. Therefore, the selection of appropriate commercial products is of crucial importance to capture the transcriptome of interest as closely to the native state as possible without introduction of technical bias. However, researchers rarely have the resources and time to test various commercial RNA-seq kits for their samples. This work reports a side-by-side comparison of RNA-seq data from Clostridium autoethanogenum obtained using three commercial rRNA removal and strand-specific library construction products by NuGEN Technologies, Qiagen, and Zymo Research and assesses their performance relative to published data. While all three vendors advertise their products as suitable for prokaryotes, we found significant differences in their performance regarding rRNA removal, strand-specificity, and, most importantly, transcript abundance distribution profiles. Notably, RNA-seq data obtained with Qiagen products were most similar to published data and delivered the best results in terms of library strandedness and transcript abundance distribution range. Our results highlight the importance of finding appropriate organism-specific workflows and library preparation products for RNA-seq studies.ImportanceRNA-seq is a powerful technique for transcriptome profiling while involving elaborate sample processing before library sequencing. Our work is important as we show that RNA-seq library preparation kits can strongly affect the outcome of the RNA-seq experiment. Although library preparation benefits from the availability of various commercial kits, choosing appropriate products for the specific samples can be challenging for new users or for users working with unconventional organisms. Evaluating the performance of different commercial products requires significant financial and time investment infeasible to most researchers. Therefore, users are often guided in their choice of kits by published data involving similar input samples. We conclude that important consideration should be given to selecting of sample processing workflows for any given organism.
MTALTND4, a second protein coded by nd4 impacts mitochondrial bioenergetics
Authors: Kienzle Laura , Bettinazzi Stefano , Brunet Marie , Choquette Thierry , Khorami Hajar Hosseini , Roucou Xavier , Landry Christian R , Angers Annie , Breton Sophie 
Published: April 2022

ABSTRACTRecent evidence suggests that the coding potential of the mitogenome is underestimated. We found a downstream alternative ATG initiation codon in the +3 reading frame of the human mitochondrial nd4 gene. This newly characterized alternative open reading frame (altORF) encodes a 99-amino acids long polypeptide, MTALTND4, which is conserved in primates. This small protein is localized in mitochondria and cytoplasm and is also found in the plasma, and it impacts mitochondrial physiology. Alternative mitochondrial peptides such as MTALTND4 may offer a new framework for the investigation of mitochondrial functions and diseases.
The anatomy of tragedy: Starbucks as a politics of displacement
Authors: Carter David B. , Warren Rebecca , Steinhoff Anne 
Published: April 2022

PurposeThis paper examines the 2012–2013 Starbucks tax crisis in the United Kingdom (UK) as an anatomy of tragedy. The tragedy in relation to Starbucks is the displacement of an opportunity to examine the relationship between financial capital and national capitalisms. The paper illustrates how the crisis displaced opportunities for substantive critique concerning financial capital, national capitalisms, multinationals, taxation and society.Design/methodology/approachAs a critical, discursive intervention, the paper examines how rhetoric was employed in 157 media articles published in six UK newspapers and on two news portals (both in print and online). The paper employs rhetorical redescription to the document archive, presenting the finding and analysis as a play in the style of an Aristotelian tragedy.FindingsAnalysis of the Starbucks approach to transfer pricing identifies misunderstandings of accounting, taxation transfer pricing, and ‘‘resolution” and how the media's construction of Starbucks as immoral, anti-British, potentially illegal operated to confuse the politics. The effect of these misunderstandings and confusion was to take attention away from a politics concerning financial capital valorisation and national capitalisms (jurisdictions raising tax revenue for government spending and social services).Originality/valueFirst, the paper explores the politics of displacement to illustrate the metonymic concealment of the primary identity of the political. Second, Aristotelian tragedy is employed to study and present methods of displacement. Third, the empirics are depicted in a dramatic format to illustrate how rhetorical interventions by the media and actors displaced the political focus away from financial capital and national capitalisms.
Improved radial basis function artificial neural network and exact-time extended state observer based non-singular rapid terminal sliding-mode control of quadrotor system
Authors: Ullah Mati , Zhao Chunhui , Maqsood Hamid 
Published: April 2022

Purpose
The purpose of this paper is to design a hybrid robust tracking controller based on an improved radial basis function artificial neural network (IRBFANN) and a novel extended-state observer for a quadrotor system with various model and parametric uncertainties and external disturbances to enhance the resiliency of the control system.

Design/methodology/approach
An IRBFANN is introduced as an adaptive compensator tool for model and parametric uncertainties in the control algorithm of non-singular rapid terminal sliding-mode control (NRTSMC). An exact-time extended state observer (ETESO) augmented with NRTSMC is designed to estimate the unknown exogenous disturbances and ensure fast states convergence while overcoming the singularity issue. The novelty of this work lies in the online updating of weight parameters of the RBFANN algorithm by using a new idea of incorporating an exponential sliding-mode effect, which makes a remarkable effort to make the control protocol adaptive to uncertain model parameters. A comparison of the proposed scheme with other conventional schemes shows its much better performance in the presence of parametric uncertainties and exogenous disturbances.

Findings
The investigated control strategy presents a robust adaptive law based on IRBFANN with a fast convergence rate and improved estimation accuracy via a novel ETESO.

Practical implications
To enhance the safety level and ensure stable flight operations by the quadrotor in the presence of high-order complex disturbances and uncertain environments, it is imperative to devise a robust control law.

Originality/value
A new idea of incorporating an exponential sliding-mode effect instead of conventional approaches in the algorithm of the RBFANN is used, which makes the control law resistant to model and parametric uncertainties. The ETESO provides rapid and accurate disturbance estimation results and updates the control law to overcome the performance degradation caused by the disturbances. Simulation results depict the effectiveness of the proposed control strategy.
Intellectual structure and pattern of publication in the International Journal of Innovation Science: a bibliometric study
Authors: Samanta Sasmita , Rautaray Bijayalaxmi , Swain Dillip K. 
Published: April 2022

Purpose
This study aims to sketch a bibliometric portrait of the International Journal of Innovation Science (IJIS) and attempts to evaluate its publication patterns from 2011 to 2020 by unfolding the key aspects of its publication trends for the audience of the journal and scholars of bibliometric studies as well.

Design/methodology/approach
This study analyzes papers published in the IJIS from 2011 to 2020 by using the required bibliometric measures to analyze the key aspects of the publishing trends of IJIS.

Findings
This study finds that a total of 487 authors published 271 articles in IJIS during 2011–2020. The USA leads the table with 89 papers followed by India (29 papers) and China (26 papers). The degree of collaboration in IJIS ranged from 0.36 to 0.94. Moreover, this study finds that the keyword “design/methodology/approach” is the central theme of research in IJIS around which all other keywords revolve.

Research limitations/implications
This study focuses on the publication patterns of the IJIS over a period of ten years. Patterns of research output in 271 publications are comprehended and analyzed. For making a ten-year bibliometric study, the papers published before 2011 were excluded from the purview of research.

Practical implications
Readers of the IJIS, teachers and research scholars interested in bibliometric studies can benefit from insights into the scholarly papers published in IJIS from 2011 to 2020.

Originality/value
This study would provide the readers of IJIS to ascertain significant contributions, top cited papers, the most prolific authors, geographical distribution of papers, keyword co-occurrence and bibliographic coupling.
Women’s empowerment to alleviate poverty in coastal zones: a case study of fisherwomen in Pacitan, Indonesia
Authors: Susilowati Indah , Mafruhah Izza 
Published: April 2022

Purpose
The purpose of this study is to identify problems that affect the empowerment of fisherwomen and to analyze the role of stakeholders in the process of empowering fisherwomen.

Design/methodology/approach
This study was a case study on 115 fisherwomen in the coastal areas of Pacitan Regency, East Java, Indonesia. The method used in this study was sequential mixed method using analytical hierarchy process analysis tool and qualitative using phenomenology by using a series of interviews with the participants.

Findings
The results show that the community empowerment process is influenced by three main factors, namely, internal, external and institutional, where each of these factors is divided into four factors. Another result obtained is that the government has an important role in empowerment which is indicated by the level of trust of fisherwomen to the government. The findings can be used as alternative guidelines to alleviate poverty of fisherwomen in coastal zones in Indonesia.

Originality/value
The formulation of an integrated fisheries system model in community empowerment innovation in coastal areas that involves all stakeholders from the government, academia, community, business and media was proposed in this study.
The long game of innovation and value creation
Authors: Klassen Mark , Wilson Grant Alexander , Dobni C. Brooke 
Published: April 2022

Purpose
The purpose of the paper is to emphasize the performance benefits of a long-term innovation and value creation perspective. This paper responds to the recent concept of the imagination premium method for valuing companies. It offers four key takeaways to create a long-term innovation-focused orientation for future value creation.

Design/methodology/approach
The research is based on both consulting experience and insight from several studies of executives that were supported by the U.S. Conference Board.

Findings
The research differentiates how high versus low innovators create long-term perspectives and value. High innovators have explicit processes that support innovation, leadership that focuses on long-term performance, resources committed to long-term projects and innovation and knowledge management systems that transfer knowledge throughout the organization.

Research limitations/implications
The research offers strategic directives aimed at creating long-term value but acknowledges that there are other means to accomplish such objectives.

Practical implications
This paper offers strategies for executives to create an innovation-focused organizational culture that drives lasting long-term value.

Social implications
Focusing on long-term innovation prioritizes larger social, environmental and business objectives over superficial short-term stock price changes, leading to greater value-creation.

Originality/value
This paper advocates that leadership play the long game and adopt a longer-term view of innovation due to its long-term competitive, employee engagement, sustainability and performance benefits.
Smart cruising: smart technology applications and their diffusion in cruise tourism
Authors: Buhalis Dimitrios , Papathanassis Alexis , Vafeidou Maria 
Published: April 2022

Purpose
This paper aims to explore and discuss the impact of digital innovations from a business eco-systemic perspective. Key smart technology application themes in the cruise industry are extracted and synthesised in a “Smart Cruise Ecosystem” (SCE) framework.

Design/methodology/approach
Information communication technologies (ICTs) advancements and smart tools revolutionise interactions and affect all transactions, transforming the cruise experience. Gradually a Smart Cruise Ecosystem emerges by incorporating all technologies available and involving cruise passengers, who as smart actors interact dynamically with stakeholders, creating value before, during and after the cruising experience. The COVID-19 pandemic outbreak stressed the need for touchless and digital interactions as well as real-time information, fast-tracking the deployment of smart technologies. The diffusion of ICTs in the cruise industry is multi-faceted and dynamic, resulting in a number of smart-technology use-cases.

Findings
Smart technology constitutes a comprehensive smart ecosystem to manage all actors, controls, devises and systems to optimise ship operations and management, while co-creating value for guests and crew in an effective way. The multiplex SCE proposed is enabled by digital technologies collecting, storing, accessing and processing big data dynamically, including: object detection, Internet of Things, Internet of Everything, satellite communications, Big Data, automation, robotics, Artificial Intelligence and Machine Learnin, Cloud Computing, Augmented, Virtual and Mixed Reality. A range of interoperable and interconnected supporting systems form the basis of the smart ecosystem.

Originality/value
The proposed framework offers a holistic perspective of the smart-cruising domain, highlighting innovations, interfaces, dependencies, along with the corresponding key limitations and challenges. The synthesis and conceptual structure provided serves as a topology for guiding and connecting further research in smart cruising.
Religiosity versus profit-loss sharing: how Islamic banks brand fidelity influence the Muslim consumers’ commitment
Authors: Junaidi Junaidi 
Published: April 2022

Purpose
The purpose of study examine the relationship between religiosity, consumers’ materialism, brand fidelity, attitude and consumers’ commitment to Islamic banking products using evidence from Indonesia.

Design/methodology/approach
The sample consists of 658 Muslim and bank consumers obtained through a survey study and using structural equation modeling to test the research hypotheses.

Findings
The empirical results indicate that religiosity has significant and positive effects on consumers’ materialism, brand fidelity and attitude, also mediating variables. Furthermore, the mediator variables partially mediate religiosity and consumers’ commitment based on consumers’ culture theory.

Research limitations/implications
This study is validated by Indonesian Muslims; therefore, future study is required to analyze across the culture and region. It can help Islamic bank managers and scholars to observe the correlation between religion, Islamic banks products and Muslims’ commitment.

Practical implications
The current study enlightened the consumers’ Islamic bank principle operation from marketing and religiosity. The government and the shariah supervisory board need to enhance the control and promote to make sure that Islamic banking operations have compliant with Islamic law.

Originality/value
The result of this study provided the Muslim decision-making process by developing and testing a model of religious determinants toward Islamic bank products.
Corporate occupiers’ attitude to flex spacein the post-Covid environment
Authors: Cooke Howard , Fiorentino Stefania , Harris Rob , Livingstone Nicola , McAllister Pat 
Published: April 2022

PurposeThis paper investigates how large UK corporate occupiers perceive the potential role of flexible office space in their office portfolios in a post-pandemic context.Design/methodology/approachThe research methodology is qualitative and applied. For a longitudinal survey, convenience sampling was used to obtain co-operation from 11 corporate real estate managers with responsibility for managing large corporate real estate portfolios spread across a range of business sectors and countries. Semi-structured interviews were selected as the core research method to seek and to optimise the balance between discovery and generalisability.FindingsAlthough the pandemic has led corporate occupiers to fundamentally re-appraise where and when different work tasks are performed, it is not yet clear whether this has major implications for the flex space sector. The flex space model, with its blending of various occupiers and activities, is perceived to be poorly aligned with an increasing emphasis on the office as a core corporate hub facilitating connection, collaboration, enculturation, learning and creativity. Since most flex space is concentrated in central locations, it is also not well positioned to benefit from any decentralisation of office functions. However, as the flex space sector evolves in response to structural shifts in employment and working practices and business change, its various products are likely to be a continuing requirement from corporate occupiers for short-term solutions to demand shocks, the need for rapid market entry, accommodation for short-term projects and access to desk space in multiple locations.Practical implicationsUnderstanding occupiers' drivers in their decision-making on selecting the method of occupation will assist investors in how they might adjust what they offer in the marketplace.Originality/valueWhilst there has been a substantive number of surveys of corporate occupiers' perceptions and intentions regarding their office portfolio, this paper focusses on a specifically on the flex space sector. Whilst previous research has mainly been extensive, this research study is intensive.