bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cáncer de mama: ¿Cuánto incide en la calidad de vida?
Authors: Elaskar María Cielo A. , Solavallone Vanina , Sola Alejandro , Gisbert Patricia , Lascano Soledad , Salomón Susana 
Published: November 2022

El cáncer de mama es la enfermedad maligna más frecuente en mujeres adultas. Considerando la calidad de vida como bienestar en diferentes ámbitos de la vida, es de interés evaluar cómo incide la enfermedad en las pacientes.
El objetivo fue determinar la calidad de vida durante el tratamiento.
Estudio protocolizado, descriptivo, a través de encuesta validada, dirigida y anónima. Se incluyeron 56 mujeres con cáncer de mama en tratamiento oncológico, de la provincia de Mendoza. Edad promedio 54.2 años. El 41% estaban casadas. Comorbilidades: HTA 34%, tabaquismo 29%, obesidad 23%. El tipo histológico predominante: carcinoma ductal infiltrante 55%. Estadio II 62%. Tratamiento con quimioterapia 91%, radioterapia 4%, hormonoterapia 5%, cirugía 79%. FACT-G (Functional Assessment of Cancer Therapy-General): Bienestar físico: 1/3 sentían falta de energía, más del 50% sintió poco dolor, más del 75% no se sintió enferma. Bienestar social: 50% se sintió cerca de amigos, más de 85% sintió apoyo familiar y 60% estuvo satisfecha con su vida sexual. Bienestar emocional: 1/4 estaban tristes, casi 80% estuvo satisfecha con cómo afrontaban la enfermedad, a más del 50% no le preocupó que la enfermedad/tratamiento ponga en riesgo su vida. Bienestar funcional: más del 60% pudieron trabajar, 66% disfrutaban su vida y aceptaban la enfermedad, 70% se sentía contenta con su calidad de vida, 73% perdió el cabello, a la mitad no les preocupó.
Las pacientes subestiman malestares, la mayoría no se sienten enfermas, están esperanzadas y satisfechas en cómo afrontaron su enfermedad. Sin embargo, la enfermedad y el tratamiento afectaron su calidad de vida, reflejándose en las esferas evaluadas.
Miocardiopatía por estrés asociada a quimioterapia
Authors: Naveira Martín , Corsico Santiago , Datri Lucas , Mendez Laura , Faura Victoria , Dutto Mauro , Romero Alfredo , Bella Quero Luciana , Korbenfeld Ernesto , Novas Cintia , Vera Karina , Silva Carlos 
Published: November 2022

La miocardiopatía por estrés es una enfermedad infrecuente caracterizada por dolor precordial típico, elevación de las enzimas cardíacas y cambios electrocardiográficos, sin evidencia de enfermedad coronaria. Es transitoria y no tiene una causa clara desencadenante, aunque el estrés emocional es un factor que pareciera estar involucrado en la mayoría de los casos comunicados.
Como consecuencia del desarrollo diagnóstico de enfermedades cardiovasculares, en los últimos 15 años aumentaron los casos, representando entre el 1-2% de los pacientes que se presentan con dolor precordial y cambios en el electrocardiograma.
La toxicidad cardiológica por la quimioterapia y otros agentes antineoplásicos es conocida, pero el síndrome de takotsubo asociado a quimioterapia es poco frecuente y sólo se registran informes de casos.
Presentamos tres pacientes con miocardiopatía por estrés asociado a quimioterapia.
Economic Degrowth and the Collapse of Institutional Order: Theory and Propositions
Authors: Lamberg Juha-Antti , Nykänen Nooa , Taskinen Jarmo 
Published: November 2022

Integrating insights from new institutional economics and studies on the collapse of past empires, we sketch a process model that links economic degrowth to the collapse of institutional orders. Our thought experiment starts from emphasizing the importance of institutions and enforcement mechanisms in maintaining a sufficient level of economic activity to sustain public costs. We flip this established logic and elucidate the negative role of economic degrowth in the weakening of the public sector’s ability to enforce institutional rules. Internal and external shocks further shake the stability of the institutional order and, at some point, individuals’ belief in institutional rules and norms weakens, resulting in system-wide collapse of the institutional order. We use historical literature on the collapse of Roman Empire as an “experimental prototype” (Meyer, Gaba, & Colwell, 2005: 471) to inspire and illustrate our thought experiment.
Femtometreistä valovuosiin: neutronitähdet eksoottisen aineen laboratoriona
Authors: Vuorinen Aleksi 
Published: November 2022

The Standard Model of particle physics describes the basic properties and interactions of all known elementary particles at an astonishingly good level, and predictions derived from it have time and again been experimentally verified. One of its parts, namely the theory of the strong nuclear interaction, Quantum Chromodynamics (QCD), has however proven to be computationally extremely demanding. In particular, the properties of matter described by QCD are at the moment still largely unknown in the limit of high baryon density.
Very recently, the study of dense QCD matter has taken important steps forward owing largely to new observational data originating from a distant but very effective laboratory: neutron stars. The cores of these extremely compact stars contain the densest form of matter in our present-day Universe, and the properties of this matter are reflected on the measurable macroscopic properties of the stars themselves. In this review article, I will introduce this active field of research, placing particular emphasis on recent efforts to discover an entirely new phase of matter - cold and dense quark matter - inside the cores of the most massive neutron stars.
Graded Care Profile, una herramienta para casos de negligencia infantil.
Authors: Expósito Antonio Luis Molina , López Moreno Rocío , Rodríguez Sánchez María Luisa 
Published: November 2022

Este artículo plantea que la herramienta Graded Care Profile (GCP) es útil en el contexto español para mejorar el trabajo con familias donde se han detectado situaciones de negligencia infantil. Identificamos características de la relación entre profesionales y familia que limitan la eficacia de programas basados en la evidencia. Siguiendo propuestas de la Evidencia basada en la práctica proponemos la relación entre profesionales y familia como factor que puede mejorar la eficacia de cualquier intervención. En este sentido, identificamos elementos de la relación entre profesionales y familia que llevan al rechazo de la intervención utilizando conceptos de Michel Foucault, en especial las relaciones de poder. Planteamos el Perfil de Niveles de Cuidados (nombre de la adaptación española del GCP) como herramienta que ayude a salvar la distancia entre investigación y práctica profesional, así como una oportunidad para trabajar la alianza terapéutica de manera complementaria a otras técnicas o instrumentos. Para llegar a esta conclusión se parte de información cualitativa aportada por profesionales que trabajan con familias con menores en situación de riesgo. Los resultados confirman que es una herramienta de aplicación asequible y que puede mejorar la estructuración de la formulación, el seguimiento del caso y los acuerdos con la familia a la que se atiende: las personas que participaron en el estudio afirmaron que la validez aparente era adecuada y que su principal ventaja era la estructuración/organización de la evaluación/tratamiento/informes. Resaltamos que el instrumento toma como objeto de evaluación la relación entre persona cuidadora y menor, compatible con una perspectiva de parentalidad positiva, y da protagonismo al punto de vista del/la menor como criterio para decidir si los cuidados son de calidad, cubren sus necesidades y se les da prioridad. Es necesario llevar a cabo más investigación para conocer las propiedades psicométricas de la adaptación española y el punto de vista de las familias respecto al instrumento.
PEMANFAATAN SEKAM PADI SEBAGAI PEMCAMPUR MEDIA TUMBUH PADA BUDIDAYA JAMUR TIRAM (Pleurotus ostreatus)
Authors: Tejo Sutejo , Sari Ariza Kurnia 
Published: November 2022

Penelitian ini bertujuan untuk mengetahui pengaruh persentase penambahan sekam padi pada media tumbuh terhadap pertumbuhan dan produksi jamur tiram putih (pleurotus ostreatus). Penelitian ini dilaksanakan di desa F Trikoyo Kecamatan Tugumulyo Kabupaten Musi Rawas, pada bulan Februari 2020 sampai dengan bulan Mei 2020, dengan ketinggian tempat 72 meter diatas permukaan laut. Penelitian ini menggunakan metode eksperimental dengan menggunakan Rancangan Acak Lengkap (RAL) non faktorial, yang terdiri dari 6 (enam) taraf perlakuan dan 4 (empat) ulangan. Adapun perlakuan persentase penambahan sekam padi adalah sebagai berikut : P0 =Penambahan 0 % Sekam Padi Perbaglog, P1=Penambahan 5 % Sekam Padi Perbaglog, P2=Penambahan 10 % Sekam Padi Perbaglog, P3 =Penambahan 15% Sekam Padi Perbaglog, P4=Penambahan 20 % Sekam Padi Perbaglog, P5 =Penambahan 30 % Sekam Padi Perbaglog. hHasil penelitian yang telah dilakukan dapat disimpulkan bahwa, Perlakuan penambahan media sekam padi 20% (P4) menunjukan hasil berpengaruh sangat nyata terhadap laju pertumbuhan misellium baglog dan bobot segar panen dan berpengaruh tidak nyata terhadap lebar tudung buah, panjang tangkai tubuh buah, diameter tangkai tubuh buah, jumlah tubuh buah.
APLIKASI KOMPOS JERAMI PADI DALAM MENINGKATKAN PERTUMBUHAN DAN PRODUKSI BEBERAPA VARIETAS TANAMAN JAGUNG MANIS (Zea mays sacharata Sturt)
Authors: Safriyani Etty , Hermanto Hermanto 
Published: November 2022

Kompos jerami padi merupakan salah satu pupuk organik yang dapat memperbaiki sifat fisik, kimis dan biologo tanah sehingga dapat meningkatkan pertumbuhan dan produksi tanaman jagung manis. Penelitian bertujuan untuk untuk mengevaluasi peran kompos jerami padi dalam meningkatkan pertumbuhan dan produksi tanaman tomat. Penelitian telah dilaksanakan di di Desa Wonosari Kecamatan Megang Sakti Kabupaten Musi Rawas. Penelitian berlangsung dari Maret sampai Mai 2021. Penelitian menggunakan rancangan acak kelompok (RAK) faktorial. Yang terdiri dua faktor perlakuan dan tiga kali ulangan. Perlakuan yang dicobakan sebagai berikut : Varietas Jagung Manis (V) yang terdiri dari:V1 = Bonanza, V2 = Secada, V3 = Paragon. Kompos Jerami Padi (J) terdiri dari: J1 = 10 ton/ha setara dengan 1,8 kg per/petak, J2 = 15 ton/ha setara dengan 2,7 kg per/ petak, J3 = 20 ton/ha setara dengan 3,6 kg per/ petak. Analisis data menggunakan analisa sidik ragam yang dilanjutkan dengan uji BNJ. Aplikasi varietas paragon (V3), kompos jerami 20 ton/ha (J3), dan interaksi varietas parago dan kompos jerami 20 ton/ha (V3J3) mengasilkan pertumbuhan dan produksi jagung manis terbaik dibanding kan dengan perlakuan lainnya.
KELAYAKAN FINASIAL DAN EKONOMI PETERNAKAN ITIK PETELUR DI KABUPATEN MUSI RAWAS
Authors: Suryati Nila , Yarda Verry , Prima Julia 
Published: November 2022

Penelitian ini bertujuan untuk menganalisis kelayakan finansial, ekonomi dan pasar usaha ternak itik petelur di Kabupaten Musi Rawas. Kriteria kelayakan usaha yang digunakan dalam penelitian ini ialah NPV, IRR, Net B/C Ratio, Payback Period dan BEP. Metode yang digunakan adalah studi kasus (Case Study) dengan penentuan lokasi secara sengaja (Purposive). Analisis kelayakan dilakukan dengan menggunakan tingkat faktor diskonto 11 % dan diperkirakan (forcasting) selama 20 tahun. Hasil analisis kelayakan finansial menunjukkan bahwa usaha ternak itik petelur di Kabupaten Musi Rawas secara finansial layak diusahakan dengan nilai NPV sebesar Rp.1.887.775.849, IRR sebesar 39 %, Net B/C Ratio sebesar 1,45, Payback Period selama 2,87 tahun, BEP Produksi sebanyak 419.413 butir dan BEP Harga sebesar Rp.2.113. Hasil analisis kelayakan ekonomi juga menunjukkan bahwa usaha ternak itik petelur di Kabupaten Musi Rawas secara ekonomi layak diusahakan dengan nilai NPV sebesar Rp.3.033.342.472, IRR sebesar 55 %, Net B/C Ratio 1,61, Payback Period 1,30 tahun, BEP Produksi sebesar 368.238 butir dan BEP Harga sebesar Rp.2.319. Berdasarkan analisis pasar, usaha ternak itik petelur di Kabupaten Musi Rawas layak diusahakan. Dilihat dari jumlah permintaan telur itik yang semakin meningkat setiap tahunnya dan adanya peluang untuk mengekspor telur itik ke luar Kabupaten Musi Rawas. Nilai estimasi kenaikan permintaan telur itik lima tahun yang akan datang yaitu sebesar 0,4% tiap tahunnya.
APLIKASI RIZOBIUM DALAM MENINGKATKAN PERTUMBUHAN DAN PRODUKSI TANAMAN KEDELAI (Glycine max (L.) Merril)
Authors: Safriyani Etty , Novi Novianto , Rian Fahrobi  
Published: November 2022

Aplikasi rhizobium pada tanaman kedelai merupakan salah satu tehnologi budidaya yang dapat mengurangi penggunaan pupuk anorganik terutama nitrogen dan menigkatkan produkstifitas tanaman. Penelitian bertujuan untuk menganalisis peran rhizobium dalam meningkatkan pertumbuhan dan produksi tanaman tanaman kedelai. Penelitian telah dilaksanakan di Kecamatan Tugumulyo Kabupaten Musi Rawas Provinsi Sumatra Selatan dengan ketinggian tempat 68 mdpl, pada bulan Februari sampai dengan Mei 2021. Penelitian menggunakan Rancangan Acak kelompok (RAK) non faktorial, terdiri dari enam perlakuan dan empat kali ulangan dengan dosis. D0 : tanpa rhizobium, D1 : 2,5 gram rhizobium/ kg benih, D2 : 5 gram rhizobium/kg benih, D3 : 7,5 gram rhizobium/ kg benih, D4 : 10 gram rhizobium/kg benih, D5 : 12,5 gram rhizobium/ kg benih. Parameter yang diamati meliputi: tinggi tanaman, jumlah cabang, kadar klorofil, jumlah polong per tanaman, bobot 100 butir, jumlah bintil akar, berat basah berangkasan, panjang akar, bobot butir pertanaman. Hasil penelitian menunjukan bahwa bahwa dosis 7,5 gram rhizobium dapat meningkatkan pertumbuhan dan produksi tanaman kedelai.
A comparison of the warming capabilities of two Baragwanath rewarming appliances with the Hotline fluid warming device
Authors: Wilson K , Fourtounas M , Anamourlis C 
Published: November 2022

Background. Accidental intraoperative hypothermia is a common and avoidable adverse event of the perioperative period and is associated with detrimental effects on multiple organ systems and postoperative patient outcomes. In a resource-limited environment, prevention of intraoperative hypothermia is often challenging. Resourceful clinicians overcome these challenges through creative devices and frugal innovations.Objective. To investigate the thermal performance of two Baragwanath Rewarming Appliances (BaRA) against that of the Hotline device to describe an optimal setup for these devices.
Methods. This was a quasi-experimental laboratory study that measured the thermal performance of two BaRA devices and the Hotline device under a number of scenarios. Independent variables including fluid type, flow rate, warming temperature and warming transit distance were sequentially altered and temperatures measured along the fluid stream. Change in temperature (ΔT) was calculated as the difference between entry and exit temperature for each combination of variables for each warming device.
Results. A total of 219 experiments were performed. At a temperature of 43.0°C and a transit distance of 200 cm, the BaRA A configuration either matched or exceeded the ΔT of the Hotline over all fluid type and flowrate combinations. The BaRA B configuration does not provide comparable thermal performance to the Hotline. Measured flowrates were noticeably slower than manufacturer-quoted values for all intravenous (IV) cannulae used.
Conclusion. A warm-water bath at 43.0°C with 200 cm of submerged IV tubing provides thermal performance comparable to the Hotline device, with all fluid type and flowrate combinations.
Alkaline Diuresis as Treatment for 2, 4-D Dimethylamine Herbicide Intoxication: A Case Report
Authors: Jindal Nitesh , Sirohi Tanu Raj , Kumar Patamsetti Anil , Shoeb Mohammad , Shabarish Gali , Sowmya Pediredla Sri 
Published: November 2022

The use of 2, 4-D dimethylamine is expanding as a result of the rise in glyphosate and paraquat resistance in weeds [1]. Instances of 2,4D dimethylamine intoxication have been on the rise. This herbicide exhibits a range of dose-dependent harmful mechanisms, including cell membrane destruction, disruption of acetyl coenzyme A metabolism, and oxidative phosphorylation uncoupling [2]. The neurological system, heart, lungs, liver, muscles, and endocrine system may all be affected by toxic effects [3]. Results in male cases are fatal [2,4]. The usefulness of alkaline diuresis as a life-saving treatment for 2,4-D dimethylamine poisoning with severe symptoms is discussed in this paper. 2, 4-D dimethylamine intoxication can be fatal if not treated promptly. There is no particular antidote and alkaline diuresis shows good result in the patient who present with severe intoxication of 2, 4-D dimethylamine.
A Study of Cancer Antigen-125 as a Diagnostic Marker in Tuberculous and Malignant Pleural Effusion
Authors: Allah Abeer Gamal Gab , Mohamed Ahmed Shawky , Hazzaa Sahar Mohey El-Din , El-Shimy Wafaa Saleh 
Published: November 2022

Background: Cancer Antigen-125 (CA-125) was first identified as an ovary-specific tumor indicator but subsequently shown that inflammation exists even in the absence of polymorphism leads to this marker to rise. Multiple locations of tuberculosis (TB) produce an increase in serum antigen levels. This research objects to estimate the diagnostic value of CA-125 and to establish the cut-off value, distinguishing tuberculous from malignant pleural effusion.
Methods: This prospective analytic case control study involved 90 subjects above 18 years old and with a confirmed diagnosis of tuberculous pleural effusion (TPE), malignant pleural effusion (MPE) and parapneumonic effusion (PPE). Subjects were equally allocated into 3 groups: group I "Tuberculous": subjects with a confirmed diagnosis of TPE, group II "Malignant": subjects with a confirmed diagnosis of MPE and group III "Control": subjects with a confirmed diagnosis of PPE.
Results: There was positive significant correlation among CA-125 in serum and pleural fluid in tuberculous effusion group (group I) and in malignant effusion group (group II).
Conclusions: For reliable detection of pleural effusion cause, serum and pleural fluid CA-125 might be included to the pleural fluid diagnostic workup.
Association of Prenatal Exposure to Benzodiazepines With Development of Autism Spectrum and Attention-Deficit/Hyperactivity Disorders
Authors: Chen Vincent Chin-Hung , Wu Shu-I , Lin Chiao-Fan , Lu Mong-Liang , Chen Yi-Lung , Stewart Robert 
Published: November 2022

ImportancePrenatal exposure to benzodiazepines is reported to be associated with neurodevelopmental disorders among children, but associations of maternal genetic confounding with neurodevelopmental disorders among children have not been taken into consideration.ObjectiveTo ascertain whether prenatal benzodiazepine exposure was associated with development of autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD).Design, Setting, and ParticipantsThis cohort study used linked data from birth certificate registration and the Taiwan National Health Insurance Research Database from January 1, 2004, to December 31, 2017, on 1 138 732 mothers with 1 516 846 live births between January 1, 2004, and December 31, 2017. Data were analyzed between February 20, 2021, and September 19, 2022.ExposureBenzodiazepine exposure during pregnancy (first trimester to third trimester) was defined as having at least one benzodiazepine prescription dispensed.Main Outcomes and MeasuresThe main outcomes were ADHD and ASD.ResultsThere were 1 516 846 children (mean [SD] gestational age, 38.5 [1.8] years; 789 455 boys [52.0%]) born full term who were younger than 14 years of age and followed up to 2017; 5.0% of the children (n = 76 411) were exposed to a benzodiazepine during pregnancy. Benzodiazepine exposure during pregnancy was associated with increased risks of ADHD (first trimester exposure: hazard ratio [HR], 1.24 [95% CI, 1.20-1.28]; second trimester exposure: HR, 1.27 [95% CI, 1.21-1.34]; third trimester exposure: HR, 1.25 [95% CI, 1.14-1.37]) and ASD (first trimester exposure: HR, 1.13 [95% CI, 1.05-1.21]; second trimester exposure: HR, 1.10 [95% CI, 0.98-1.22]; third trimester exposure: HR, 1.21 [95% CI, 1.00-1.47]). However, no differences were found with unexposed sibling controls during the same time frame for ADHD (first trimester exposure: HR, 0.91 [95% CI, 0.83-1.00]; second trimester exposure: HR, 0.89 [95% CI, 0.78-1.01]; third trimester exposure: HR, 1.08 [95% CI, 0.83-1.41]) or ASD (first trimester exposure: HR, 0.92 [95% CI, 0.75-1.14]; second trimester exposure: HR, 0.97 [95% CI, 0.71-1.33]; third trimester exposure: HR, 1.07 [95% CI, 0.53-2.16]). Similar findings were also noted in the stratification analysis of short-acting and long-acting benzodiazepines.Conclusions and RelevanceThis cohort study suggests that previously described adverse neurodevelopmental outcomes associated with benzodiazepine exposure during pregnancy were likely to be accounted for by maternal genetic confounding.
Near‐Infrared Mechanoluminescence of Cr3+ Doped Gallate Spinel and Magnetoplumbite Smart Materials
Authors: Liu Shengqiang , Zheng Yuantian , Peng Dengfeng , Zhao Jing , Song Zhen , Liu Quanlin 
Published: November 2022

AbstractMechanoluminescence (ML), as an optical response to deformation stimuli, shows great potential in high‐end stress sensing, ultrasonic field visualization, and multidimensional anti‐counterfeiting. However, processive practical applications in bio‐medicine are constrained by the discovery of near‐infrared (NIR) ML materials. Unlike lanthanides (Ln3+) with sharp multiplets, two kinds of Cr3+‐doped NIR ML materials, gallate spinel (ZnGa2O4:Cr3+, Zn3Ga2GeO8:Cr3+) and gallate magnetoplumbite (SrGa12O19:Cr3+) are here reported. Owing to the intrinsic cation antisite defects and cation vacancies in the matrix, these materials exhibit bright NIR ML under a relatively low load (20 N). In particular for SrGa12O19:Cr3+ (750 nm, peak; 100 nm, FWHM) with low persistent luminescence (PersL) interference, the ML behavior can be further rejuvenated under UV and sunlight irradiation. SrGa12O19:Cr3+ also shows bright NIR emission under photo‐ and thermo‐stimulation. Owing to their excellent tissue penetration and concealment capability, NIR ML materials show great potential in the fields of bio‐medicine and anti‐counterfeiting.
Room‐Temperature Metal‐Catalyzed Ultrafast Gasification of Ultrathin Boron Flakes
Authors: Liu Shizhuo , Liao PeiChi , Wei Wei , Han Erxun , Wang Yunkun , Tian Huifeng , Li Ruijie , Pan Jiaqi , Zhang Chi , Li Hao , Li Yifei , Yao Zhixin , Li Zhenjiang , Yang Zhang Lina , Li Zhiyun , Huang Rong , Gao Yunan , Guo Junjie , Chen Ji , Cui Yi , Liu Lei 
Published: November 2022

AbstractThe trivalent outer shell of boron renders this element electron‐poor but chemically rich, exhibiting more than one dozen allotropes. Its 2D polymorph has been recently synthesized on metal substrates under ultrahigh vacuum and has attracted intense interest. However, probing its properties ex situ has been challenging due to the quality degradation—surface oxidation—that occurs upon exposure to ambient environments. Herein, this surface chemistry is investigated in regard to the air stability of ultrathin boron flakes on metals prepared by atmospheric‐pressure chemical vapor deposition. The characteristic Volmer–Weber growth is recognized by the stacking of polygon‐shaped, thin flakes as isolated islands. Significantly, the metal‐catalyzed, ultrafast gasification of boron flakes at room temperature, exemplified by the complete, spontaneous vanishment of 200 nm‐thick boron islands in 3 h is observed. A two‐step mechanism, first oxygen‐involved surface oxidation and then subsequent reactions with water forming a highly volatile boric acid layer, is unambiguously revealed by combined surface characterizations. The catalysis by metal substrates, corroborated by theoretical calculations, is attributed as the crucial cause of the unprecedented gasification. The concept of oxygen‐free growth is thereby proposed for air‐sensitive material growth by introducing in situ oxygen scavengers. These findings significantly expand the fundamental understanding of the surface chemistry of boron and pave the way for the chemical vapor deposition growth of hydrophobic materials.