bluuebunny/crossref_metadata_2025_split huggingface dataset:
Governance structures, cultural distance, and socialization dynamics: further challenges for the modern corporation
Authors: Cordes Christian , Müller Stephan , Schwesinger Georg , Lundan Sarianna M. 
Published: May 2022

AbstractThis paper relates cultural distance and governance structures. We suggest a model of cultural evolution that captures the idiosyncratic socialization dynamics taking place in groups of communicating and interacting agents. Based on these processes, cultural distance within and between groups or organizational units develops. Transaction cost theorists associate higher cultural distance with higher transaction costs. Therefore, one problem of economic organization is assessing alternative governance structures in terms of the socialization dynamics they enable that entail different intraorganizational transaction costs. Socialization governance structures that can be used to affect cultural distance among employees include shared social experiences in groups, the assignment of influential role models, group sizes, the recruitment of employees presocialized in certain ways, the recognition of specific cultural dimensions such as “individualism” or “collectivism”, and the implementation of cooperative cultures in business units. These yield organizations differential capacities to adapt internal structures in transaction cost-minimizing ways.
Improved Outcomes of Thermal Ablation for Colorectal Liver Metastases: A 10-Year Analysis from the Prospective Amsterdam CORE Registry (AmCORE)
Authors: Puijk Robbert S. , Dijkstra Madelon , van den Bemd Bente A. T. , Ruarus Alette H. , Nieuwenhuizen Sanne , Geboers Bart , Timmer Florentine E. F. , Schouten Evelien A. C. , de Vries Jan J. J. , van der Meijs Bram B. , Nielsen Karin , Swijnenburg Rutger-Jan , van den Tol M. Petrousjka , Versteeg Kathelijn S. , Lissenberg-Witte Birgit I. , Scheffer Hester J. , Meijerink Martijn R. 
Published: May 2022

Abstract
Background
To analyze long-term oncological outcomes of open and percutaneous thermal ablation in the treatment of patients with colorectal liver metastases (CRLM).

Methods
This assessment from a prospective, longitudinal tumor registry included 329 patients who underwent 541 procedures for 1350 CRLM from January 2010 to February 2021. Three cohorts were formed: 2010–2013 (129 procedures [53 percutaneous]), 2014–2017 (206 procedures [121 percutaneous]) and 2018–2021 (206 procedures [135 percutaneous]). Local tumor progression-free survival (LTPFS) and overall survival (OS) data were estimated using the Kaplan–Meier method. Potential confounding factors were analyzed with uni- and multivariable Cox regression analyses.

Results
LTPFS improved significantly over time for percutaneous ablations (2-year LTPFS 37.7% vs. 69.0% vs. 86.3%, respectively, P < .0001), while LTPFS for open ablations remained reasonably stable (2-year LTPFS 87.1% [2010–2013], vs. 92.7% [2014–2017] vs. 90.2% [2018–2021], P = .12). In the latter cohort (2018–2021), the open approach was no longer superior regarding LTPFS (P = .125). No differences between the three cohorts were found regarding OS (P = .088), length of hospital stay (open approach, P = .065; percutaneous approach, P = .054), and rate and severity of complications (P = .404). The rate and severity of complications favored the percutaneous approach in all three cohorts (P = .002).

Conclusion
Over the last 10 years efficacy of percutaneous ablations has improved remarkably for the treatment of CRLM. Oncological outcomes seem to have reached results following open ablation. Given its minimal invasive character and shorter length of hospital stay, whenever feasible, percutaneous procedures may be favored over an open approach.
The awareness of radiologists for the presence of lateral lymph nodes in patients with locally advanced rectal cancer: a single-centre, retrospective cohort study
Authors: Sluckin T. C. , Rooker Y. F. L. , Kol S. Q. , Hazen S. J. A. , Tuynman J. B. , Stoker J. , Tanis P. J. , Horsthuis K. , Kusters M. 
Published: May 2022

Abstract
Objectives
Enlarged lateral lymph nodes (LLNs) are associated with increased (lateral) local recurrence rates. Size and anatomical location should therefore always be reported by radiologists and discussed during multidisciplinary meetings. The objective was to investigate how often LLNs are mentioned in MRI reports in a tertiary referral centre.

Methods
A single - centre, retrospective study of 202 patients treated for primary rectal cancer between 2012 and 2020, with at least a T2 tumour located within 12cm of the anorectal junction. The radiology reports were written by 30–40 consultant radiologists. MRI scans were independently re-assessed by an expert radiologist. The primary outcome was how often the presence or absence of LLNs was mentioned in the initial report.

Results
Primary MRI reports explicitly mentioned the presence or absence of LLNs in 89 (44%) cases. Of the 43 reports with present LLNs, only one (1%) reported on all features such as size, location or malignant features. Expert review revealed 17 LLNs which were ≥ 7 mm (short-axis); two of these were not mentioned in the original reports. In 14/43 (33%) cases, LLNs were discussed during the primary multidisciplinary meeting, while 17/43 (40%) restaging MRI reports failed to report on the previously visible LLN. Reporting LLNs increased significantly with higher N-stage (p = .010) and over time (p = .042).

Conclusions
Though improving with time, there is still limited consistency in reporting LLNs. Only 44% of primary MRI reports mentioned LLNs and relevant features of those LLNs were seldomly reported. Given the importance of this information for subsequent treatment; increased awareness, proper training and the use of templates are needed.

Key Points
• Comprehensive reporting of lateral lymph nodes in primary MRI reports was limited to less than 50%.
• Lateral lymph nodes are not always discussed during primary multidisciplinary meetings or mentioned in restaging reports.
• Improvements in the awareness and knowledge of lateral lymph nodes are needed to ensure adequate multidisciplinary treatment decisions.
Developments in the study of volcanic and igneous plumbing systems: outstanding problems and new opportunities
Authors: Burchardt Steffi , Annen Catherine J. , Kavanagh Janine L. , Hilmi Hazim Suraya 
Published: May 2022

AbstractPrior to and during eruptions, magma is stored and transported within volcanic and igneous plumbing systems (VIPS) that comprise a network of magma reservoirs and sheet intrusions. The study of these VIPS requires the combination of knowledge from the fields of igneous petrology, geochemistry, thermodynamic modelling, structural geology, volcano geodesy, and geophysics, which express the physical, chemical, and thermal complexity of the processes involved, and how these processes change spatially and temporally. In this contribution, we review the development of the discipline of plumbing system studies in the past two decades considering three angles: (1) the conceptual models of VIPS and paradigm changes, (2) methodological advances, and (3) the diversity of the scientific community involved in VIPS research. We also discuss future opportunities and challenges related to these three topics.
Effects of temperature on the movement and feeding behaviour of the large lupine beetle, Sitona gressorius
Authors: Hannigan Sara , Nendel Claas , Krull Marcos 
Published: May 2022

AbstractEven though the effects of insect pests on global agricultural productivity are well recognised, little is known about movement and dispersal of many species, especially in the context of global warming. This work evaluates how temperature and light conditions affect different movement metrics and the feeding rate of the large lupine beetle, an agricultural pest responsible for widespread damage in leguminous crops. By using video recordings, the movement of 384 beetles was digitally analysed under six different temperatures and light conditions in the laboratory. Bayesian linear mixed-effect models were used to analyse the data. Furthermore, the effects of temperature on the daily diffusion coefficient of beetles were estimated by using hidden Markov models and random walk simulations. Results of this work show that temperature, light conditions, and beetles’ weight were the main factors affecting the flight probability, displacement, time being active and the speed of beetles. Significant variations were also observed in all evaluated metrics. On average, beetles exposed to light conditions and higher temperatures had higher mean speed and flight probability. However, beetles tended to stay more active at higher temperatures and less active at intermediate temperatures, around 20 °C. Therefore, both the diffusion coefficient and displacement of beetles were lower at intermediate temperatures. These results show that the movement behaviour and feeding rates of beetles can present different relationships in the function of temperature. It also shows that using a single diffusion coefficient for insects in spatially explicit models may lead to over- or underestimation of pest spread.
The effect of mindfulness training on resting-state networks in pre-adolescent children with sub-clinical anxiety related attention impairments
Authors: Kennedy Michelle , Mohamed Abdalla Z. , Schwenn Paul , Beaudequin Denise , Shan Zack , Hermens Daniel F. , Lagopoulos Jim 
Published: May 2022

AbstractMindfulness training has been associated with improved attention and affect regulation in preadolescent children with anxiety related attention impairments, however little is known about the underlying neurobiology. This study sought to investigate the impact of mindfulness training on functional connectivity of attention and limbic brain networks in pre-adolescents. A total of 47 children with anxiety and/or attention issues (aged 9-11 years) participated in a 10-week mindfulness intervention. Anxiety and attention measures and resting-state fMRI were completed at pre- and post-intervention. Sustained attention was measured using the Conners Continuous Performance Test, while the anxiety levels were measured using the Spence Children’s Anxiety Scale. Functional networks were estimated using independent-component analysis, and voxel-based analysis was used to determine the difference between the time-points to identify the effect of the intervention on the functional connectivity. There was a significant decrease in anxiety symptoms and improvement in attention scores following the intervention. From a network perspective, the results showed increased functional connectivity post intervention in the salience and fronto-parietal networks as well as the medial-inferior temporal component of the default mode network. Positive correlations were identified in the fronto-parietal network with Hit Response Time and the Spence Children’s Anxiety Scale total and between the default mode network and Hit Response Time. A 10-week mindfulness intervention in children was associated with a reduction in anxiety related attention impairments, which corresponded with concomitant changes in functional connectivity.
Verschwörungsdenken, Wahn und Virtualität
Authors: Fuchs Thomas 
Published: May 2022

Zusammenfassung„Nichts ist, wie es scheint“, „nichts geschieht zufällig“, und „alles ist miteinander verbunden“ – diese drei Grundannahmen charakterisieren Verschwörungstheorien unterschiedlicher Provenienz. Damit zeigen sie eine deutliche Parallelität zur Struktur von paranoidem Bedeutungserleben und Wahn. Dem stehen jedoch wichtige Unterschiede gegenüber, etwa die Bildung ausgedehnter Gruppen von Verschwörungsgläubigen, denen keine paranoiden „Wahngemeinschaften“ entsprechen. Der Aufsatz untersucht zunächst beide Phänomene vergleichend und wendet sich dann der Frage zu, wie die Virtualisierung der Kommunikation in den sozialen Medien die Bildung von verschwörungstheoretischen Gemeinschaften begünstigt.
Ohne geht’s nicht mehr
Authors: Iser Angelika 
Published: May 2022

ZusammenfassungSeit 2008 gibt es an der Fakultät für angewandte Sozialwissenschaften der Hochschule München ein Peer-Coaching-Angebot von Studierenden für Studierende im Bachelorstudiengang Soziale Arbeit. Im Lauf der Zeit hat es sich ausgeweitet und bewährt, gerade auch in den Pandemie-Semestern. Der Beitrag blickt zurück auf die Entwicklung des Angebots seit seiner Einführung und schlussfolgert, dass es künftig weiter ausgebaut und sich spätestens 2035 als feste Größe im Studium der Hochschule München etabliert haben wird.
The role of parenting behavior’s on the intergenerational covariation of grit
Authors: Fernández-Martín Francisco D. , Arco-Tirado José L. , Mitrea Elena-Cristina , Littvay Levente 
Published: May 2022

AbstractThis study evaluates parental grit’s covariation with offspring grit and the moderating role of different parenting behaviors using an 11-country study of young adults between the ages of 18 and 35 (n = 20,008) and their parents (n = 5945). Results show that parental grit is associated with offspring’s grit with moderation of parenting present across the models presented. The study also highlights the direct association of various parenting dimensions with grit, especially the positive relation of parental control. These results have important implications for understanding young people’s grit development and learning mechanisms. Findings can serve as foundations for effective intervention programs and practices in this field designed to improve enthusiasm, interest, capacity for hard work, engagement, and motivation in the long run.
Social Economic Benefits of an Underground Heritage: Measuring Willingness to Pay for Karst Caves in Italy
Authors: Benedetto G. , Madau F. A. , Carzedda M. , Marangon F. , Troiano S. 
Published: May 2022

Abstract
Karst caves are widespread in Europe, especially in the Mediterranean area. Besides their purely environmental functions, they often are important tourist destinations and contribute to the so-called identity amenities or landscape beauties of a territory. In spite of their interest and tourism potential, economists have paid little attention to karst caves and their economic value. In this paper, the contingent valuation method (CVM) was applied to investigate tourists’ preferences and estimate the monetary value attributed to karst caves, and in particular to the Pradis Caves, Friuli Venezia Giulia region (Italy). 540 visitors of the area took part in a face-to-face contingent valuation survey. Mean willingness-to-pay was equal to € 5.37. When scaled up to the population, gross social benefit was estimated in about € 23 K/year. Findings suggest that the karst cave value could have a significant impact on the social welfare gains or losses, and inform the karst cave-use management debate concerning the trade-offs of developing tourism activities. The estimated values allow institutional decision makers to identify the volume of financial resources to be put into play for interventions aimed at protection and conservation of this environmental asset.
Log Fano blowups of mixed products of projective spaces and their effective cones
Authors: Grange Tim , Postinghel Elisa , Prendergast-Smith Artie 
Published: May 2022

AbstractWe compute the cones of effective divisors on blowups of $$\mathbb P^1 \times \mathbb P^2$$

P
1

×

P
2

and $$\mathbb P^1 \times \mathbb P^3$$

P
1

×

P
3

in up to 6 points. We also show that all these varieties are log Fano, giving a conceptual explanation for the fact that all the cones we compute are rational polyhedral.
Applied Behavior Analysis in Children and Youth with Autism Spectrum Disorders: A Scoping Review
Authors: Gitimoghaddam Mojgan , Chichkine Natalia , McArthur Laura , Sangha Sarabjit S. , Symington Vivien 
Published: May 2022

AbstractThis manuscript provides a comprehensive overview of the impact of applied behavior analysis (ABA) on children and youth with autism spectrum disorders (ASD). Seven online databases and identified systematic reviews were searched for published, peer-reviewed, English-language studies examining the impact of ABA on health outcomes. Measured outcomes were classified into eight categories: cognitive, language, social/communication, problem behavior, adaptive behavior, emotional, autism symptoms, and quality of life (QoL) outcomes. Improvements were observed across seven of the eight outcome measures. There were no included studies that measured subject QoL. Moreover, of 770 included study records, only 32 (4%) assessed ABA impact, had a comparison to a control or other intervention, and did not rely on mastery of specific skills to mark improvement. Results reinforce the need for large-scale prospective studies that compare ABA with other non-ABA interventions and include measurements of subject QoL to provide policy makers with valuable information on the impacts of ABA and other existing and emerging interventions.
Schamhafte und schamlose Armut bei Ulrich Bräker
Authors: Widder Roman 
Published: May 2022

ZusammenfassungDer Aufsatz untersucht das Verhältnis von Scham und Armut im Werk Ulrich Bräkers: Die Lebensgeschichte und Natürliche Ebentheuer des Armen Mannes im Tockenburg (1789) ist an der Vorbildlichkeit schamhafter Armut orientiert, ringt jedoch mit der paradoxen Notwendigkeit der schamlosen Inszenierung schamhafter Armut. Die Rede über den Gassenbettel (1790) zeichnet sich demgegenüber durch experimentelle Strategien der Beschämung des Publikums mithilfe einer Rhetorik der Evidenz und der Zeugenschaft aus. Die in Bräkers Tagebüchern enthaltene Jauss-Novelle (1789) schließlich, die hier erstmals einer genaueren Betrachtung unterzogen wird, kreist um eine Figur schamloser Armut und sexueller Ausschweifung. Dass die in ihrer obszönen Explizitheit erstaunliche Jauss-Novelle nie vollständig und im Zusammenhang als literarisches Werk publiziert wurde, führt vor Augen, dass Scham eine Schlüsselfunktion für die Selektionsmechanismen des literarischen Betriebs besitzt.
Systemic response to Fusarium graminearum and culmorum inoculations: changes in detoxification of flag leaves in wheat
Authors: Gallé Ágnes , Pelsőczi Alina , Benyó Dániel , Podmaniczki Anna , Szabó-Hevér Ágnes , Poór Péter , Tóth Beáta , Horváth Edit , Erdei László , Csiszár Jolán 
Published: May 2022

AbstractFusarium graminearum and F. culmorum cause the most widespread wheat disease Fusarium head blight (FHB). The present study describes that the Fusarium inoculation of the wheat spikes caused systemic changes in the key elements of the antioxidant/detoxification defence system in the flag leaf during the grain filling period in wheat lines differing in biotic stress susceptibility to explore changes in some components of the response. According to our data, the inoculation with both F. graminearum and F. culmorum at the anthesis changed significantly the activities of superoxide dismutase (SOD) and guaiacol peroxidase (POD) enzymes, as well as the glutathione transferase (GST) activity in the flag leaves of the selected wheat lines approx. two weeks later after the infection. In silico approach supported the expressional up-regulation of various GST genes upon Fusarium infection. Based on our results, GST sequences TaGSTF26 and TaGSTU120 were among the series of important stress response genes, which were transcriptionally up-regulated, thus possibly playing a role in the systemic response to Fusarium infection, where TaGSTF26 might have an important role in the successful defence. These GSTs can serve as effective markers of the detoxification process for breeders and plant protection in the future.
Human Myometrial and Uterine Fibroid Stem Cell-Derived Organoids for Intervening the Pathophysiology of Uterine Fibroid
Authors: Banerjee Saswati , Xu Wei , Chowdhury Indrajit , Driss Adel , Ali Mohamed , Yang Qiwei , Al-Hendy Ayman , Thompson Winston E. 
Published: May 2022

Abstract
Uterine fibroids (UFs) (leiomyomas or myomas) are the most common clonal neoplasms of the uterus in women of reproductive age worldwide. UFs originate from myometrium consist of smooth muscle and fibroblast components, in addition to a substantial amount of fibrous extracellular matrix which all contribute to the pathogenetic process. Current treatments are primarily limited to surgical and interventional. Here, we have established a novel and promising organoid model from both normal and patient myometrial stem cells (MMSCs). MMSCs embedded in Matrigel in stem cell media swiftly formed organoids which successfully proliferate and self-organized into complex structures developing a sustainable organoid culture that maintain their capacity to differentiate into the different cell types recapitulating their tissue of origin and shows responsiveness to the reproductive hormones (estrogen and progesterone). Gene expression analysis and structural features indicated the early onset of uterine fibrosis led to the accumulation of extracellular matrix suggesting the potential use of this model in better understanding of the pathophysiology associated with UFs and inventing novel therapeutics for the treatment of UFs.
A framework for assessing AI ethics with applications to cybersecurity
Authors: Bruschi Danilo , Diomede Nicla 
Published: May 2022

AbstractIn the last few years many scholars, public and private organizations have been involved in the definition of guidelines and frameworks for individuating the principles to adopt in the development and deployment of AI systems. Some authors, however, noted that the effectiveness of these guidelines or ethical codes on the developer’s community is very marginal. One of the obstacles that opposes to the effective implementation of ethical principles is the lack of an approach for solving tensions which arise when principles are applied. A possible solution to such an issue could be the adoption of a risk-based approach which is also advocated by many sources. To our knowledge, no concrete proposals have been presented in literature on how to perform a risk-based ethical assessment. In this paper we contribute to close this gap by introducing a framework based on a qualitative risk analysis approach for assessing the ethical impact underneath the introduction of an innovation either technological or organizational in a system. We will also show how the framework can be used for individuating suitable safeguards to adopt for balancing potential ethical infringements that the innovation may entail once implemented. Some case studies in the cybersecurity context are also described for showing the effectiveness of our approach.
Meaningful human control of drones: exploring human–machine teaming, informed by four different ethical perspectives
Authors: Steen Marc , van Diggelen Jurriaan , Timan Tjerk , van der Stap Nanda 
Published: May 2022

AbstractA human-centric approach to the design and deployment of AI systems aims to support and augment human capabilities. This sounds worthwhile indeed. But what could this look like in a military context? We explored a human-centric approach to the design and deployment of highly autonomous, unarmed Unmanned Aerial Vehicle (UAV), or drone, and an associated Decision Support System (DSS), for the drone’s operator. We explore how Human–Machine Teaming, through such a DSS, can promote Meaningful Human Control of the drone. We use four different ethical perspectives—utilitarianism, deontology, relational ethics and virtue ethics—to discuss different ways to design and deploy the drones and the DSS. Our aim is to explore ways to support and augment the operators’ capabilities.