bluuebunny/crossref_metadata_2025_split huggingface dataset:
The development of a hybrid model to forecast paddy water temperature as an alert system for high‐temperature damage
Authors: Xie Wenpeng , Kimura Masaomi , Asada Yohei , Iida Toshiaki , Kubo Naritaka 
Published: February 2022

AbstractClimate change has led to increasing global air temperatures. In the field of crop cultivation, long‐term high temperatures (heatwaves) during the rice‐growing season might increase the risk of high‐temperature damage to rice, which might result in reductions to the yield and quality of rice. In this study, a hybrid forecast model consisting of a combined paddy field heat balance model and a meteorological forecast model is proposed for predicting 1‐day‐ahead water temperatures as an alert system for high‐temperature damage to paddy fields, with resolution in terms of hours. The results show close agreement between the measured and predicted water temperatures, and the high‐temperature alert accuracy was 88.5%. Additionally, the climate resilience of paddy fields was investigated by using the rising annual temperatures due to climate change. The observations indicate that while paddy fields are sensitive to the climate, their climate resilience can be improved through artificial measures. Farmers and managers of paddy fields can thus be made aware of the water temperatures of the paddy fields in advance to enable reasonable management of water resources and avoid high‐temperature damages caused by extreme weather conditions.
Renal tubular dysfunction and cancer mortality in the Japanese general population living in cadmium‐non‐contaminated areas
Authors: Nogawa Kazuhiro , Watanabe Yuuka , Sakuma Sayaka , Sakurai Masaru , Nishijo Muneko , Ishizaki Masao , Morikawa Yuko , Kido Teruhiko , Nakagawa Hideaki , Suwazono Yasushi 
Published: February 2022

AbstractThe relationship between cadmium exposure, exposure‐related renal tubular dysfunction, and mortality have been reported, mainly in the residents of Cd‐contaminated areas in Japan. The aim of this study was to establish the cause–effect relationship between renal tubular dysfunction and cancer mortality in the general population in non‐contaminated areas. A 19‐year cohort study was conducted in 1110 men and 1703 women in 1993 or 1994, who lived in three cadmium‐non‐contaminated areas. Mortality risk ratios of urinary β2‐microglobulin (β2MG) and N‐acetyl‐β‐glucosaminidase (NAG) for all malignant neoplasms and specific cancers were estimated using the Fine and Gray competing risks regression model. Significant hazard ratios (HRs) for liver and pancreas cancer were observed for NAG (liver: HR corresponding to an increase of 1 IU/g cr, 1.10, 95%CI, 1.02–1.19, pancreas: HR, 1.10, 95%CI, 1.02–1.19) in men. In women, a negative HR was observed for NAG (lung cancer: HR 0.80, 95% CI, 0.67–0.96) and for β2MG (all malignant neoplasms: HR, 0.97, 95% CI, 0.93–1.00). The present study indicated that renal tubular dysfunction was significantly related to mortality in the general population of cadmium‐non‐contaminated areas in Japan.
Assessment of communication and physical exam skills: A comparison of students, faculty and standardized patients
Authors: Cuevas‐Nunez Maria Carolina , Pulido M. Teresa , Harpe Spencer , Stein Amy B , Lempicki Kelly 
Published: February 2022

AbstractPurpose/objectivesThe objective of this retrospective study was twofold: it aimed to investigate dental students’ communication and physical exam self‐assessment skills by comparing students’ self‐evaluations with those completed by faculty and standardized patients (SPs). Second, it aimed to compare faculty and SPs assessment of students’ communication skills.MethodsAt the end of their first year of training, students (n = 127), participated in one SP encounter about an initial dental consultation. Students completed self‐assessment before receiving feedback from faculty (n = 19) and SPs (n = 19). The data source included evaluation forms submitted by students, faculty and SPs. The Wilcoxon signed rank test was used to compare the overall scores between groups. Agreement between evaluations items were analyzed with McNemar's test (p < 0.05).ResultsOverall, there were no statistically significant differences in how students and faculty graded for either communication (p = 0.6724) or physical exam (p = 0.1921) skills. However, both students and faculty provided less favorable marks than SPs for communication skills with a statistically significant difference in the overall grading between both students and SPs (p = 0.0146) and between faculty and SPs (p = 0.0045).ConclusionsWhile there was disagreement between students and faculty versus SPs, they weren't meaningful differences in scores and the dissimilarities mainly consisted of ratings of explanation skills. We suggest that, when applicable, dental student's self‐evaluations may represent an alternative to faculty assessments of communication and physical exam skills. Nonetheless, we recommend that SPs be included in the assessment of communication skills to provide students with comprehensive feedback that more realistically represents the natural patient‐provider relationship.
Junior faculty perspectives on the academic environment: A call for development and onboarding
Authors: Mays Keith A. , Burns Lorel E. , Branch‐Mays Grishondra , Quock Ryan 
Published: February 2022

AbstractBackgroundOne challenge in dental education is new faculty members can be hired with limited teaching experience or understanding of pedagogy. Recent publications document increasing initiatives of faculty development in US and Canadian dental schools. This study evaluates full‐time faculty perspectives of their develop and academic environment.MethodsA 33‐item questionnaire distributed to senior administrators and forwarded to faculty, collected data on demographics and satisfaction, utilizing a 5‐item Likert scale, multiple choice, and binary yes/no questions. Responses were descriptively and statistically analyzed utilizing an analysis of variance, chi‐square, and two‐sample t‐test.ResultsThere were 183 faculty respondents (37.7% male/62.3% female), age ranges were 20–29 (2.2%), 30–39 (53.5%), and 41–49(44.3). Respondents reported race/ethnicity: Caucasian (60.7%), Asian (19.1%), Hispanic (12.6%), Black/African American (5.5%), two or more races (2.2%), and Native American 0%. Length of employment was significantly associated with primary responsibility (p = 0.0023), recent publications (p < 0.0011), and short‐term intent to remain in academia (p = 0.046). There was a statistically significant difference between age and satisfaction with professional development (p = 0.0411), achieving career objectives (p = 0.0151), well‐being (p = 0.0492), access to resources for scholarly interests (p = 0.0114), communication (p = 0.0058), and assessment training (p = 0.0249). Non‐Caucasian faculty reported greater dissatisfaction with being treated respectfully (p = 0.0302), departmental commitment to diversity and inclusion (p = 0.0075), and departmental cooperation/teamwork (p = 0.0323).ConclusionsA significant number of junior faculty have interest in academic dental careers. Institutions should invest in improving onboarding and professional development. Improve the early experiences of faculty, and foster diversity and inclusion and faculty well‐being.
Neural signatures of the development of antisocial behaviours and callous‐unemotional traits among youth: The moderating role of parental support
Authors: Huffman Landry Goodgame , Oshri Assaf 
Published: February 2022

AbstractComorbidity of antisocial behaviours (AB) and callous‐unemotional (CU) traits characterizes a subgroup of youth at risk for chronic and severe AB in adulthood. Although aberrant neural response to facial emotion confers heightened risk for AB and CU traits, the behavioural effect of this neural response varies by family context. The present study examines the effects of neural response to emotional faces, parental support and the interaction between the two as predictors of AB and CU traits in a longitudinal sample of preadolescents (Nbaseline = 11,883; Mage = 9.5; 47.8% female). Low CU youth who evinced attenuated response to fearful faces within the left superior temporal sulcus and fusiform gyrus showed smaller decreases of AB over time; these associations did not extend to high CU youth. Among high CU youth reporting low parental support, blunted response to fearful faces within the bilateral inferior parietal sulcus predicted smaller decreases of AB. Study findings highlight neurobehavioural differences between youth with high and low CU traits, as well as the interacting roles of negative face processing and parental support in the development of AB.
Postnatal depletion of serotonin affects the morphology of neurons and the function of the hippocampus in male rats
Authors: Ghaheri Safa , Niapour Ali , Sakhaie Nona , Sadegzadeh Farshid , Saadati Hakimeh 
Published: February 2022

AbstractSerotonin (5‐HT) is an essential neurotransmitter for the refined organization of the cerebral cortex. Studies have suggested that altered serotonin signaling contributes to cognitive impairment and psychiatric disorders. However, the exact role of this neurotransmitter on the development of hippocampal neurons is not recognized. Here we aimed to examine the effects of the para‐chlorophenylalanine (PCPA; 100 mg/kg/daily, s.c. during the postnatal days 10–20), a reversible inhibitor of 5‐HT synthesis, on the serotonin level of the hippocampal and prefrontal cortex. We also focused on the morphology of the neurons in the hippocampus and spatial learning and memory. Our results indicated that the administration of PCPA led to a decrease in serotonin levels in the hippocampus and prefrontal cortex. Postnatal serotonin depletion also induced subtle alterations in the neuronal populations of the hippocampus and impaired spatial memory in the adulthood period of life. We found that critical developmental periods of serotonin depletion caused degeneration and swelling of neurons as well as significant neuronal loss in the hippocampal CA1, CA3, and dentate gyrus (DG) areas. Thus, serotonin, a strikingly important neurotransmitter, can affect neuronal morphology, development, and hippocampal‐dependent memory.
Representing soil health practice effects on soil properties and nutrient loss in a watershed‐scale hydrologic model
Authors: Evenson Grey , Osterholz William Robert , Shedekar Vinayak S. , King Kevin , Mehan Sushant , Kalcic Margaret 
Published: February 2022

AbstractWatershed‐scale hydrologic models are commonly used to assess the water quality effects of agricultural conservation practices that improve soil health (e.g., cover crops and no‐till). However, models rarely account for how these practices (i.e., soil health practices) affect soil physical and functional properties such as water holding capacity and soil aggregate stability, which may, in turn, affect water quality. We introduce a method to represent changes in soil physical and functional properties caused by soil health practices in the Soil and Water Assessment Tool (SWAT) model. We used the SWAT model's default representation of winter cover crops and no‐till and modified soil descriptive parameters to depict soil health practice effects on soil properties. We assumed that the soil health practices would increase soil organic carbon (SOC), a principal indicator of soil health, by 0.01 g C g–1 of soil and then estimated changes in other soil properties (e.g., water holding capacity) using SOC‐based predictive equations and preceding literature. Results indicated that our soil property modifications had statistically significant effects on simulated hydrology and nutrient loss, though outputs were more substantially affected by the model's default representation of cover crops and no‐till. Results also indicated that soil health practices can reduce nitrogen and total phosphorus loss but may increase dissolved reactive phosphorus loss. Our representation of soil health practices provides a more complete estimate of practice efficacy but underscores a need for additional observational data to verify results and guide further model improvements.
Effect of previous conventional irinotecan treatment in patients with pancreatic cancer being treated with liposomal irinotecan plus 5‐fluorouracil and leucovorin
Authors: Chiu Tai‐Jan , Yang Shih‐Hung , Chiu Sz‐Chi , Hsueh Shun‐Wen , Chiang Nai‐Jung , Li Chung‐Pin , Bai Li‐Yuan , Cheng Fu‐Ming , Chuang Shih‐Chang , Shan Yan‐Shen , Chan De‐Chuan , Chen Li‐Tzong , Yen Chia‐Jui , Peng Cheng‐Ming , Su Yung‐Yeh , Chen Yen‐Yang , Chen Jen‐Shi , Chou Wen‐Chi 
Published: February 2022

AbstractBackgroundRecent studies have suggested the suboptimal efficacy of liposomal irinotecan plus 5‐fluorouracil/leucovorin (nal‐IRI+5‐FU/LV) in metastatic pancreatic ductal adenocarcinoma (mPDAC) patients previously treated with conventional irinotecan. This study investigated the effect of conventional irinotecan treatment in mPDAC patients receiving nal‐IRI+5‐FU/LV by analyzing a population‐based dataset.MethodsWe reviewed 667 consecutive mPDAC patients treated with nal‐IRI+5‐FU/LV between August 2018 and November 2020 at Taiwanese medical centers. Eighty‐six patients previously treated with conventional irinotecan were matched to 86 patients not treated with conventional irinotecan, following propensity matching for age, sex, performance status, metastatic organ site, pre‐treatment carbohydrate antigen 19‐9 level, lines of prior chemotherapy treatment, and time from first‐line treatment to nal‐IRI+5‐FU/LV therapy.ResultsThe median overall survival and time‐to‐treatment failure were 4.8 and 2.6 vs 4.1 and 2.1 months, respectively, for patients who were and were not previously treated with conventional irinotecan. The tumor response and disease control rates were 5.8% and 32.6% vs 5.8% and 37.2%, respectively, for patients previously treated and not treated with conventional irinotecan. No significant differences were observed in survival times and tumor response rates between the two groups.ConclusionsPrevious conventional irinotecan treatment does not compromise the efficacy of subsequent nal‐IRI+5‐FU/LV treatment in mPDAC patients.
Evaluation of antibody response after two doses of the Sinovac vaccine and the potential need for booster doses in cancer patients
Authors: Ata Serdar , Cil Timucin , Duman Berna B. , Unal Nevzat 
Published: February 2022

AbstractSevere acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) is more severe in some specific patient groups, such as cancer patients with a mortality rate of 26.5%. The main way of protection is vaccination. In this study, we aimed to evaluate the antibody responses of our cancer patients who received two doses of the inactivated COVID‐19 vaccine manufactured by Sinovac Life Sciences. Patients over the age of 18, who had not been suspected or polymerase chain reaction‐confirmed COVID‐19 positive, who received two doses of the vaccine, and at least 28 days passed after the second dose, and who received at least one dose of cancer treatment before the vaccination—were included in the study. Immunoglobulin class G antibodies against the receptor binding region (S‐RBD) of the spike protein S1 subunit of SARS‐CoV‐2 were studied. A total of 200 patients with a diagnosis of cancer were included in the study. The median time between the second dose of the Sinovac vaccine and the time of blood collection was 3.44 (3.20−3.84) months. SARS‐CoV‐2 antibody positivity was detected in 110 (55%) patients. The two subgroups with the highest antibody levels were gynecological cancers and breast cancers, with median 158.5 AU/ml (38.4−764.5) and 106.3 AU/ml (61.9−162.9) levels, respectively. Antibody positivity rate was 46.8% in patients who received chemotherapy at any time between the first dose of the vaccine and the date of blood collection; and it was 73.8% in the group that did not receive chemotherapy (p < 0.001). As a result, the expected antibody response was not obtained with two doses of the Sinovac vaccine. Therefore, if the Sinovac vaccine is to be preferred for these patients, the appropriate booster time for the third dose should be determined or other vaccines, such as messenger RNA vaccines, with reported higher antibody responses should be considered.
Using text mining and crowdsourcing platforms to build employer brand in the US banking industry
Authors: Sajid Soman , Volkova Natalia , Wilson Joseph Ato , Opoku‐Asante Emmanuel 
Published: February 2022

AbstractCrowdsourcing platforms are a valuable source of information for employees and firms. They have become an essential part of human resource practices, such as recruiting, employee engagement, and the marketing of a company's brand. Crowdsourcing platforms can help enrich an employer's brand, with employee reviews acting as a terra‐incognita for the early‐stages in the employer branding process. In response to these dynamics, this research explores the employer value proposition preferences and the sentiments of employees in the US banking industry. Approximately 11,000 reviews on the crowdsourcing platform Indeed.com, covering the top 18 banks listed on the Fortune 500, were parsed. The text mining techniques topic modeling and sentiment analysis were carried out using Latent Dirichlet Allocation. The topic modeling analysis revealed work‐life balance, management, economic, social, and development values as the most preferred employer value proposition, while brand‐image, application, and interest values were the least preferred. Sentiment analysis showed that employees exhibit negative sentiments for management, work stress, work‐life balance, and economic values, and show positive sentiments for development, social, and interest values. The paper highlights avenues for future research and discusses the managerial and theoretical implications for managers and HR practitioners.
Examining well‐being in posttraumatic stress disorder treatment: An explorative study
Authors: Radstaak Mirjam , Hüning Laura , Lamers Sanne , Bohlmeijer Ernst T. 
Published: February 2022

AbstractAlthough the importance of well‐being in mental health is widely acknowledged, well‐being as a predictor of and outcome in the treatment for posttraumatic stress disorder (PTSD) has received little attention. This naturalistic study aimed to investigate well‐being in the context of care‐as‐usual treatment for PTSD. Patients with PTSD attending a community mental health center (N = 318) completed measures of well‐being and PTSD symptoms before and after symptom‐focused treatment. Following treatment, well‐being increased among patients with PTSD, with emotional, d = −0.25, and psychological well‐being, d = ‐0.24, showing the largest improvements relative to social well‐being, d = −0.15. Although levels of well‐being improved overall within the sample, participant scores on measures of well‐being remained low compared with the general population. Well‐being predicted treatment efficiency such that participants with more severe PTSD symptoms benefitted more from care‐as‐usual treatment when they reported relatively high levels of well‐being at the start of treatment. The findings suggest a benefit to including well‐being as a pretreatment and outcome variable when evaluating PTSD treatments.
Posttraumatic growth during the COVID‐19 lockdown: A large‐scale population‐based study among Norwegian adolescents
Authors: Ulset Vidar Sandsaunet , von Soest Tilmann 
Published: February 2022

AbstractThe negative consequences of the COVID‐19 lockdown during the spring of 2020 have been documented. However, adolescents may also have experienced positive personal and interrelational changes. This was the first study to examine the prevalence of posttraumatic growth (PTG) during the lockdown. We additionally explored how potential risk and protective factors, as well as experiences with the pandemic, were related to PTG and whether these associations were moderated by mental health resources and social support. We used data from a representative survey of 12,686 junior and senior high school students from Oslo, Norway, conducted during the lockdown (37% response rate, 56.4% girls). A short version of the Posttraumatic Growth Inventory was used to assess growth relative to personal strength, relationships with others, and appreciation of life. Several potential predictors in the domains of mental health, social relationships, experiences during the pandemic, and sociodemographic background factors were examined. Results from multiple regression analyses showed that satisfaction with life, parental care, worries about the pandemic, and immigrant status were the most prominent predictors of PTG, βs = .14–.22, p < .001. Moderation analyses indicated a complex interplay between predictors of PTG by showing that good mental health was associated with higher degrees of PTG only in groups typically considered to be at higher risk of adverse outcomes. The findings provide information regarding who would profit from additional help to reinterpret the dramatic events during the lockdown to facilitate growth.
Impact of residual air trap in balloon on laser treatment of tubular tissue
Authors: Lim Seonghee , Truong Van Gia , Kang Hyun Wook 
Published: February 2022

AbstractObjectivesTubular tissue, such as the bile duct and esophagus, often suffers from stenosis due to chronic inflammation or excessive contraction of smooth muscle. Laser treatment using a balloon catheter has been used to treat tubular tissue stenosis by mechanically expanding the tissue and irradiating laser light circumferentially on the tissue lumen. As the balloon is inflated with saline, the residual air in a delivery channel is often accumulated in the inflated balloon. Thus, the air trap may cause physical discontinuities at air‐saline interface, leading to unpredictable and nonuniform photothermal interactions. The aim of the current study was to evaluate the optical‐thermal effects of the air trap in the balloon on laser treatment of the tubular tissue by means of numerical simulations and experimental validations.Materials and MethodsA balloon‐assisted diffusing applicator (BDA) was developed to inflate a balloon and deliver uniform and circumferential laser light. Before the balloon inflation, various numbers of deflations (0, 1, 2, 3, and 4) were applied to estimate the average amount of the air removed from the balloon. Ex vivo experiments using porcine liver duct were conducted with two deflation conditions (D0: no deflation for air trap and D3: three deflations for no air trap). The balloon was horizontally situated during laser irradiation to maintain the air trap at the same position in the balloon by minimizing gravity effect. Upon balloon inflation, 532 nm laser light was delivered through the BDA to the tissue (irradiance = 4 W/cm2) at 10 W for 45 seconds to assess the optical‐thermal effects of the air trap on the ductal tissue.ResultsThe size of the air trap was noticeably reduced with the number of deflations. The air trap volume in the balloon decreased to 0.5% of the total balloon volume after D3. Ex vivo results demonstrated that thicker coagulative necrosis (CN) for D0 near the air trap region in the tissue than bottom region that contact with saline, representing an asymmetric profile of CN in the tissue. D0 generated 17% thicker and nonuniform CN (overall CN thickness = 1.4 ± 0.7 mm), compared with D3 with no air trap (overall CN thickness = 1.2 ± 0.2 mm; p < 0.05). A threefold larger eccentricity (E) was found in D0 (49 ± 31%) than D3 (15 ± 13%; p < 0.001).ConclusionBoth numerical simulations and experiments validated the effect of the air trap in a balloon on the distribution of CN in a tubular tissue during BDA‐assisted laser treatment. Further in vivo studies will assess the current findings on the air trap for clinical translations of BDA‐assisted laser treatment of tubular tissue stenosis.