bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acute proximal left anterior descending coronary artery occlusion presenting with Normal ECG: A case report
Authors: Hu Yuecheng , Jin Dongxia , Liu Chunwei , Zhang Rui , Zhou Shiying , Wang Le , Cong Hongliang 
Published: September 2022

AbstractThe middle‐aged male was diagnosed with “acute anterior wall myocardial infarction” based on clinical symptoms, laboratory examination, and coronary angiography (CAG), but his ECG showed no significant change in QRS wave or ST‐T within 6 h of admission. Thus, a perfect explanation with the existing theory is difficult, and only the case is presented here.
Penalised, post‐pretest, and post‐shrinkage strategies in nonlinear growth models
Authors: Piladaeng Janjira , Ejaz Ahmed S. , Lisawadi Supranee 
Published: September 2022

SummaryIn nonlinear growth models, we considered the parameter estimation under subspace information for low‐dimensional and high‐dimensional data. We proposed novel estimators based on pretest and shrinkage strategies to improve the estimation efficiency and to establish asymptotic properties. We used simulation studies and a real data example to confirm the theoretical results. We also applied two well‐known penalised methods—least absolute shrinkage and selection operator (LASSO) and adaptive LASSO (aLASSO)—for the dimensional reduction of the predictor variables. The results demonstrated that the pretest and shrinkage estimation strategies performed well in parameter estimations when the subspace information was incorrect for both low‐ and high‐dimensional regimes.
Study on the source of raw material and firing technique of glazed tiles bodies in the Ming Imperial palace site, Nanjing, China
Authors: Zhao Weijuan , Zhao Dan , Chen Qinlong , Wu Bo , Li Xiang , Cui Jianfeng , Li Jihong , Li Bo 
Published: September 2022

AbstractThis article considered glazed tiles excavated from the Ming Imperial Palace site in Nanjing as the research object. Glazed tiles were selected and analyzed via vacuum porosimeter, thermal dilation (TD), X‐ray diffraction (XRD), and energy dispersive X‐ray fluorescence (EDXRF) to determine their physical property, firing temperature, phase composition, and chemical composition, respectively. Results show that the firing temperature of body belongs to the temperature range (of 950–1,100°C), whereas the water absorption and apparent porosity are large. The phase composition of glazed tile bodies is the same (predominantly quartz and mullite). However, some samples contain trace amounts of rutile, hematite, sodalite, and orthoclase. The firing temperature combined with the phase composition indicates that the raw material and firing process of glazed tile body samples have similarities, which embody of the strict and unified management system of the official kiln. The raw materials of glazed tile body in the Ming Imperial Palace site may come from Dangtu glazed kiln, whereas the rest of the samples remains to be explored. This study provides a scientific basis for understanding the evolution of glazed tile‐making technology in ancient China, and is important for the protection and repair of glazed buildings in the Ming Dynasty.
Different modes of synaptic and extrasynaptic NMDA receptor alteration in the hippocampus of P301S tau transgenic mice
Authors: Alfaro‐Ruiz Rocío , Aguado Carolina , Martín‐Belmonte Alejandro , Moreno‐Martínez Ana Esther , Merchán‐Rubira Jesús , Hernández Félix , Ávila Jesús , Fukazawa Yugo , Luján Rafael 
Published: September 2022

AbstractN‐methyl‐d‐aspartate receptors (NMDARs) are pivotal players in the synaptic transmission and synaptic plasticity underlying learning and memory. Accordingly, dysfunction of NMDARs has been implicated in the pathophysiology of Alzheimer disease (AD). Here, we used histoblot and sodium dodecylsulphate‐digested freeze‐fracture replica labelling (SDS‐FRL) techniques to investigate the expression and subcellular localisation of GluN1, the obligatory subunit of NMDARs, in the hippocampus of P301S mice. Histoblots showed that GluN1 expression was significantly reduced in the hippocampus of P301S mice in a laminar‐specific manner at 10 months of age but was unaltered at 3 months. Using the SDS‐FRL technique, excitatory synapses and extrasynaptic sites on spines of pyramidal cells and interneuron dendrites were analysed throughout all dendritic layers in the CA1 field. Our ultrastructural approach revealed a high density of GluN1 in synaptic sites and a substantially lower density at extrasynaptic sites. Labelling density for GluN1 in excitatory synapses established on spines was significantly reduced in P301S mice, compared with age‐matched wild‐type mice, in the stratum oriens (so), stratum radiatum (sr) and stratum lacunosum‐moleculare (slm). Density for synaptic GluN1 on interneuron dendrites was significantly reduced in P301S mice in the so and sr but unaltered in the slm. Labelling density for GluN1 at extrasynaptic sites showed no significant differences in pyramidal cells, and only increased density in the interneuron dendrites of the sr. This differential alteration of synaptic versus extrasynaptic NMDARs supports the notion that the progressive accumulation of phospho‐tau is associated with changes in NMDARs, in the absence of amyloid‐β pathology, and may be involved in the mechanisms causing abnormal network activity of the hippocampal circuit.
Associations of depressive symptoms with white matter abnormalities and regional cerebral blood flow in patients with amnestic mild cognitive impairment
Authors: Hirao Kentaro , Yamashita Fumio , Kato Hikaru , Kaneshiro Kyoko , Tsugawa Akito , Haime Rieko , Fukasawa Raita , Sato Tomohiko , Kanetaka Hidekazu , Umahara Takahiko , Sakurai Hirofumi , Hanyu Haruo , Shimizu Soichiro 
Published: September 2022

AimDepressive symptoms are one of the most common neuropsychiatric symptoms in patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD), although the pathophysiologies of the depressive symptoms that occur in these diseases have not been elucidated to date. In this study, we therefore investigated the associations between depressive symptoms and cognitive performance, white matter abnormalities, and regional cerebral blood flow (rCBF) in amnestic MCI patients.MethodsThirty‐eight patients with amnestic MCI were analyzed. The volumes of periventricular hyperintensities (PVH) and deep white matter hyperintensities (DWMH) were measured on T2‐fluid‐attenuated inversion recovery magnetic resonance imaging using the imaging software 3D‐slicer. Associations between the Geriatric Depression Scale (GDS) score and other neuropsychological test scores on the one hand and the PVH and DWMH volumes on the other were analyzed. Voxel‐wise correlations of rCBF with GDS score, after controlling for the effects of age, were investigated using SPM8 software.ResultsSignificant correlations were identified between GDS score, Trail Making Test B and apathy scale scores on the one hand and PVH volume on the other. A significant negative association between GDS score and rCBF was identified in the right dominant bilateral dorsolateral prefrontal cortex (DLPFC).ConclusionsDepressive symptoms are significantly associated with PVH volume in MCI patients. The rCBF of the DLPFC was significantly associated with depressive symptoms, suggesting that this area might be closely involved in the pathogenesis of the depressive symptoms observed in MCI patients. Geriatr Gerontol Int 2022; 22: 846–850.
Public administration and political science: Can this marriage be saved?
Authors: Kettl Donald F. 
Published: September 2022

AbstractThere is a profound irony in how public administration and political science splintered at the very pinnacle of their interconnection, intellectual power, and practical impact. Much of public administration has gradually separated from political science. Then public administration broke into pieces, with public administration and public management going in different directions. The central question is this: Are these tensions the product of diverging intellectual trends, or of fundamental organizational changes in higher education? B. Guy Peters, Jon Pierre, Eva Sorensen, and Jacob Torfing argue that political science and public administration have reached a “bifurcation” that is nothing less than a “divorce.” As I note in this paper, the wedges in this division are deep, and the basic theoretical and practical challenges are forcing it wider. It is time to ask: Can this marriage be saved? Is this a marriage that should be allowed to wither away? If the divorce becomes final, what might we lose in the split?
Widening or narrowing inequalities? The equity implications of digital tools to support COVID‐19 contact tracing: A qualitative study
Authors: O'Donnell Catherine A. , Macdonald Sara , Browne Susan , Albanese Alessio , Blane David , Ibbotson Tracy , Laidlaw Lynn , Heaney David , Lowe David J. 
Published: September 2022

AbstractBackgroundAs digital tools are increasingly used to support COVID‐19 contact tracing, the equity implications must be considered. As part of a study to understand the public's views of digital contact tracing tools developed for the national ‘Test and Protect’ programme in Scotland, we aimed to explore the views of groups often excluded from such discussions. This paper reports on their views about the potential for contact tracing to exacerbate inequalities.MethodsA qualitative study was carried out; interviews were conducted with key informants from organizations supporting people in marginalized situations, followed by interviews and focus groups with people recruited from these groups. Participants included, or represented, minority ethnic groups, asylum seekers and refugees and those experiencing multiple disadvantage including severe and enduring poverty.ResultsA total of 42 people participated: 13 key informants and 29 members of the public. While public participants were supportive of contact tracing, key informants raised concerns. Both sets of participants spoke about how contact tracing, and its associated digital tools, might increase inequalities. Barriers included finances (inability to afford smartphones or the data to ensure access to the internet); language (digital tools were available only in English and required a degree of literacy, even for English speakers); and trust (many marginalized groups distrusted statutory organizations and there were concerns that data may be passed to other organizations). One strength was that NHS Scotland, the data guardian, is seen as a generally trustworthy organization. Poverty was recognized as a barrier to people's ability to self‐isolate. Some participants were concerned about giving contact details of individuals who might struggle to self‐isolate for financial reasons.ConclusionsThe impact of contact tracing and associated digital tools on marginalized populations needs careful monitoring. This should include the contact tracing process and the ability of people to self‐isolate. Regular clear messaging from trusted groups and community members could help maintain trust and participation in the programme.Patient and Public ContributionOur patient and public involvement coapplicant, L. L., was involved in all aspects of the study including coauthorship. Interim results were presented to our local Public and Patient Involvement and Engagement Group, who commented on interpretation and made suggestions about further recruitment.
Compression strength of tungsten carbide–cobalt hard metals
Authors: Swab Jeffrey J. , Pittari John J. 
Published: September 2022

AbstractEight tungsten carbide (WC) materials containing different cobalt (Co) contents (3‒12 wt.%) and with different WC grain sizes (.4‒1.85 μm) were subjected to compressive loading under quasi‐static and dynamic conditions using a dumbbell‐shaped specimen geometry. The materials exhibited varying degrees of inelastic strain prior to final fracture under both loading conditions. Inelastic strain was consistent under dynamic loading but varied with Co content and WC grain size under quasi‐static loading. The only material to exhibit a strain‐rate‐dependent compression strength was the material containing the highest level of Co (12%) and the largest WC grain size (1.85 μm) indicating a potential threshold level of Co content and/or WC grain size where the compressive strength is insensitive to the strain rate.
Are socially responsible exchange‐traded funds paying off in performance?
Authors: Dai Ya , Guo Liang , Liu Steve , Zhang Hongxian 
Published: September 2022

AbstractThis study examines the Socially Responsible (SR) exchange‐traded funds (ETFs) by comparing their risk‐adjusted performance with a matched group of conventional ETFs in the U.S. equity market. In contrast to prior studies that focus on actively managed mutual funds, we find that the risk‐adjusted returns of SR ETFs are significantly lower than those of conventional ETFs during the 2005–2020 period. Such underperformance is only observed in non‐crisis periods but not in economic crisis periods (i.e., the 2020 pandemic recession and 2008 financial turmoil). We attribute the observed underperformance of SR ETFs during the non‐crisis periods to their limited diversification of unsystematic risks resulting from various negative or positive screens employed in the funds. We also find that net fund flows of the SR ETFs are less sensitive to past negative performance than are conventional fund flows. Collectively, our findings suggest that, instead of seeking wealth maximization, socially conscious investors may choose SR ETFs to gain non‐economic utility.
Symptom‐based case definitions for COVID‐19: Time and geographical variations for detection at hospital admission among 260,000 patients
Authors: Baruch Joaquin , Rojek Amanda , Kartsonaki Christiana , Vijayaraghavan Bharath K. T. , Gonçalves Bronner P. , Pritchard Mark G. , Merson Laura , Dunning Jake , Hall Matthew , Sigfrid Louise , Citarella Barbara W. , Murthy Srinivas , Yeabah Trokon O. , Olliaro Piero ,   ISARIC Clinical Characterisation Group
Published: September 2022

AbstractIntroductionCase definitions are used to guide clinical practice, surveillance and research protocols. However, how they identify COVID‐19‐hospitalised patients is not fully understood. We analysed the proportion of hospitalised patients with laboratory‐confirmed COVID‐19, in the ISARIC prospective cohort study database, meeting widely used case definitions.MethodsPatients were assessed using the Centers for Disease Control (CDC), European Centre for Disease Prevention and Control (ECDC), World Health Organization (WHO) and UK Health Security Agency (UKHSA) case definitions by age, region and time. Case fatality ratios (CFRs) and symptoms of those who did and who did not meet the case definitions were evaluated. Patients with incomplete data and non‐laboratory‐confirmed test result were excluded.ResultsA total of 263,218 of the patients (42%) in the ISARIC database were included. Most patients (90.4%) were from Europe and Central Asia. The proportions of patients meeting the case definitions were 56.8% (WHO), 74.4% (UKHSA), 81.6% (ECDC) and 82.3% (CDC). For each case definition, patients at the extremes of age distribution met the criteria less frequently than those aged 30 to 70 years; geographical and time variations were also observed. Estimated CFRs were similar for the patients who met the case definitions. However, when more patients did not meet the case definition, the CFR increased.ConclusionsThe performance of case definitions might be different in different regions and may change over time. Similarly concerning is the fact that older patients often did not meet case definitions, risking delayed medical care. While epidemiologists must balance their analytics with field applicability, ongoing revision of case definitions is necessary to improve patient care through early diagnosis and limit potential nosocomial spread.
Nasal Staphylococcus aureus and S. pseudintermedius carriage in healthy dogs and cats: a systematic review of their antibiotic resistance, virulence and genetic lineages of zoonotic relevance
Authors: Abdullahi Idris Nasir , Zarazaga Myriam , Campaña-Burguet Allelén , Eguizábal Paula , Lozano Carmen , Torres Carmen 
Published: September 2022

Abstract
The molecular ecology of Staphylococcus aureus, Staphylococcus pseudintermedius and their methicillin-resistant strains in healthy dogs and cats could serve as good models to understand the concept of bacterial zoonosis due to animal companionship. This study aims to provide insights into pooled prevalence, genetic lineages, virulence and antimicrobial resistance (AMR) among healthy dogs and cats. Original research and brief communication articles published from 2001 to 2021 that reported the nasal detection of S. aureus and S. pseudintermedius in healthy dogs and cats in the community, homes and outside veterinary clinics were examined and analysed. Forty-nine studies were eligible and included in this systematic review. The pooled prevalence of nasal carriage of S. aureus/methicillin-resistant S. aureus (MRSA) in healthy dogs and cats were 10.9% (95% CI: 10.1–11.9)/2.8% (95% CI: 2.4–3.2) and 3.2% (95% CI: 1.9–4.8)/0.5% (95% CI: 0.0–1.1), respectively. Conversely, the pooled prevalence of S. pseudintermedius/methicillin-resistant S. pseudintermedius (MRSP) in healthy dogs and cats were 18.3% (95% CI: 17.1–19.7)/3.1% (95% CI: 2.5–3.7) and 1.3% (95% CI: 0.6–2.4)/1.2% (95% CI: 0.6–2.3), respectively. Although highly diverse genetic lineages of S. aureus were detected in healthy dogs and cats, MSSA-CC1/CC5/CC22/CC45/CC121/CC398 and MRSA-CC5/CC93/CC22/CC30 were mostly reported in dogs; and MSSA-CC5/CC8/CC15/CC48 and MRSA-CC22/CC30/CC80 in cats. Of note, MSSA-CC398 isolates (spa-types t034 and t5883) were detected in dogs. Genetic lineages often associated with MSSP/MRSP were ST20/ST71, highlighting the frequent detection of the epidemic European MRSP-ST71 clone in dogs. S. aureus isolates carrying the luk-S/F-PV, tst, eta, etb and etd genes were seldomly detected in dogs, and luk-S/F-PV was the unique virulence factor reported in isolates of cats. S. pseudintermedius isolates harbouring the luk-S/F-I, seint and expA genes were frequently found, especially in dogs. High and diverse rates of AMR were noted, especially among MRSA/MRSP isolates. There is a need for additional studies on the molecular characterization of isolates from countries with under-studied nasal staphylococci isolates.
Integrative review: Factors impacting effective delegation practices by registered nurses to assistants in nursing
Authors: Crevacore Carol , Jacob Elisabeth , Coventry Linda L. , Duffield Christine 
Published: September 2022

AbstractAimTo identify the evidence on factors that impact delegation practices by Registered Nurses to Assistants in Nursing in acute care hospitals.DesignAn integrative review.Data SourcesDatabase searches were conducted between July 2011 and July 2021.Review MethodsWe used the 12‐step approach by Kable and colleagues to document the search strategy. The (Whittemore & Knafl. 2005. Journal of Advanced Nursing, 52(5), 546–553) integrative review framework method was adopted and the methodological quality of the studies was assessed using Joanna Briggs critical appraisal instruments.ResultsNine studies were included. Delegation between the Registered Nurse and the Assistant in Nursing is a complex but critical leadership skill which is impacted by the Registered Nurse's understanding of the Assistant in Nursing's role, scope of practice and job description. Newly qualified nurses lacked the necessary leadership skills to delegate. Further education on delegation is required in pre‐registration studies and during nurses' careers to ensure Registered Nurses are equipped with the skills and knowledge to delegate effectively.ConclusionWith increasing numbers of Assistants in Nursing working in the acute care environment, it is essential that Registered Nurses are equipped with the appropriate leadership skills to ensure safe delegation practice.
A new species of Geophagus (Teleostei: Cichlidae): Naming a cichlid species widely known in the aquarium hobby as ‘Geophagus sp. Tapajos red head’
Authors: Chuctaya Junior , Nitschke Pedro , Andrade Marcelo C. , Wingert Juliana , Malabarba Luiz R. 
Published: September 2022

AbstractA new species of Geophagus sensu stricto is described from the Tapajos River basin, Brazil, elevating the number of species of the genus to 21. The new species is of commercial importance and is known in the aquarist trade as Geophagus ‘red head’. The new species is diagnosed using an integrative approach, based on mitochondrial DNA analysis along with morphological evidence. The new species is distinguished from all congeners by the absence of markings on the head, the bar pattern composed by nine vertical bars on the flanks and the presence of distinct longitudinal bands in the caudal fin. Additionally, it shows a genetic distance of at least 2.0% in cytochrome b gene sequences from its closest congeners. Molecular analysis including most genera of Cichlidae from South America corroborates that the new species belongs to the group of Geophagus sensu stricto.
A new species of deep‐water Lethrinops (Cichlidae) from Lake Malawi
Authors: Turner George F. 
Published: September 2022

AbstractA new species of cichlid fish, Lethrinops atrilabris is described from specimens collected by trawling at a depth of around 90 m off Monkey Bay, southern Lake Malawi. It is assigned to the genus Lethrinops on the basis of its vertical flank barring, lack of enlarged cephalic lateral line canal pores and the form of the lower jaw dental arcade. It can be distinguished from congeneric species by its male breeding dress of contrasting flank barring and dark ventral surface, most strikingly on the lips, throat and chest, its relatively small known maximum size [<75 mm standard length (SL)], large eyes (38%–41% head length), laterally compressed body (depth 2.5–2.7 times max head width) and lower gill raker count (13–14).
Meta‐analysis of fractional radiofrequency treatment for acne and/or acne scars
Authors: Li Jing , Duan Fangfang , Kuang Jie 
Published: September 2022

AbstractBackgroundFractional radiofrequency (FRF) is increasingly used for acne scars. The common coexistence of acne scars and active acne is a challenge in the timely management of acne scarring.AimsWe conducted a systematic review and meta‐analysis to compare the efficacy and safety of FRF treatment with the lasers for acne and/or acne scars.MethodsA systematic search was performed on PubMed, Embase, Ovid, Cochrane Library, and Web of Science. Compared with the lasers, a meta‐analysis was conducted to assess the clinical improvement and adverse events after FRF treatment.ResultsEight randomized controlled trials were included. FRF group was more effective than the laser group in patient‐evaluated acne improvement (RR = 1.35, 95% CI: 1.01 ∼ 1.80). Regardless of observer assessment or patient evaluation, the FRF group was as effective as the laser group in treating atrophic acne scars (RR = 0.92, 95% CI: 0.78 ∼ 1.08; RR =1.15, 95% CI: 0.99 ∼ 1.34). Although there was no difference in pain level and crusting time between the two groups (SMD =0.20, 95% CI: −0.72 ∼ 1.12; SMD = −0.93, 95% CI: −2.38 ∼ 0.52), PIH incidence of FRF was significantly lower than that of the laser group (RR = 0.12, 95% CI: 0.04 ∼ 0.35). The duration of erythema after FRF treatment was also obviously shorter than that after the laser treatment (SMD = −0.78, 95% CI: −1.37 ∼ −0.18). Subgroup analysis showed that at least a 12‐week follow‐up was required to observe the full effects of FRF.ConclusionsFRF could be a better choice for atrophic acne scar patients with active acne. FRF is superior in treating atrophic acne scar patients prone to pigmentation.