bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy Analysis of Multidisciplinary Treatment for Wilm’s Tumor in a Single Center
Authors: Ji Fengming , Wu Chengchuang , Li Ye , Zhang Huangchenghao , Li Jinrong , Li Li , Yang Zhen , Yan Bing 
Published: December 2022

Abstract
Objective
To analyze the efficacy of multidisciplinary treatment (MDT) for Wilm’s tumor (WT) in Kunming Children’s Hospital, and investigate the risk factors affecting the prognosis of WT.
Method
The clinic-pathological data were collected and analyzed in patients with unilateral WT treated in Kunming Children's Hospital from January 2017 to July 2021. Research objects were selected according to inclusion criteria and exclusion criteria. The risk factors and independent risk factors that affect the prognosis of patients with WT were determined by Kaplan-Meier survival analysis and Cox proportional hazards model, respectively.
Outcome:
A total of 68 children were included in this study, and the 5-year overall survival (OS) rate was 92.65%. Kaplan-Meier survival analysis results showed that ethnicity (P = 0.020), the tumor volume of resection (P = 0.001), histological type (P < 0.001), and postoperative recurrence (P < 0.001) were the factors affecting the prognosis of children with WT. The results of the Cox proportional hazards model showed that only the histological type (P = 0.028) was the independent risk factor for the prognosis of WT.
Conclusion
The efficacy of MDT for WT was satisfying. The histological type has important predictive value for the prognosis of WT, and the patient with unfavorable histology has a poor prognosis.
Correlation of serum sodium,serum potassium concentrations and their ratios with blood pressure in older patients
Authors: Li Jingjing , Li Gang 
Published: December 2022

Abstract
Background
Several studies have investigated the relationship between dietary or urine potassium and sodium and blood pressure, but few have evaluated the relationship between serum potassium or sodium and blood pressure. Therefore, we evaluated the association between serum potassium and sodium and blood pressure in an older Chinese population.
Methods
A total of 241 older patients admitted to Hebei General Hospital were consecutively enrolled. 150 patients were divided into hypertension group and 91 patients were divided into normal blood pressure group. Correlation analysis and multiple logistic regression were used to analyze the relationship between serum sodium, serum potassium and their ratio with blood pressure. Receiver operating characteristic (ROC) curve was used to analyze the predictive value of serum sodium/potassium ratio for hypertension in this population.
Results
Serum potassium was negatively correlated with systolic blood pressure (r=-0.341, P < 0.001), serum sodium-to-potassium ratio was positively correlated with systolic blood pressure (r = 0.349, P < 0.001), and serum sodium was not significantly correlated with systolic blood pressure (r = 0.105, P < 0.001). Serum sodium/potassium concentration ratio (OR = 1.094, 95%CI 1.003–1.193, P = 0.043) was still an independent influencing factor of hypertension. The area under ROC curve of serum sodium-to-potassium ratio for predicting hypertension in older patients was 0.666 (95%CI 0.599–0.733, P < 0.001).
Conclusions
Serum potassium level is related to blood pressure in the older population, and serum sodium-to-potassium ratio is related to hypertension in the older patients, which is an independent risk factor for hypertension in this population.
Prediction of emergency department visits in home healthcare patients: a case-control study in Taiwan
Authors: Jian Jia-Wei , Tsai Kang-Ting , Ho Chung-Han , Chen Yi-Chen , Li Pi-I , Hsu Chien-Chin , Lin Hung-Jung , Chang Chi-Chen , Huang Chien-Cheng 
Published: December 2022

Abstract
Background: Home healthcare (HHC) is an important care choice for elderly people with disabilities; however, the risk factors for emergency department (ED) visits, a poor outcome index, remain unclear. Therefore, we conducted this study to clarify it.
Methods: We conducted a case-control study from a medical center in Taiwan by identifying HHC patients between Aug 1, 2019, and July 31, 2021. Age, sex, iatrogenesis, underlying comorbidities, and ED visit data were collected. Univariable and multivariable logistic regression analyses were performed to identify independent predictors of ED visits.
Results: We identified 240 patients, including 133 patients with and 107 patients without ED visits, for this study. The mean ages were 83.9 and 83.3 years and females accounted for 71% and 60.9% of patients without and with ED visits, respectively. Multivariable logistic regression analyses showed that urinary catheters (adjusted odds ratio [aOR]: 5.84; 95% confidence interval [CI]: 1.48−23.01, p = 0.012) and peptic ulcer disease (PUD)/gastroesophageal reflux disease (GERD) (aOR: 2.27; 95% CI: 1.12−4.61, p = 0.023) were independent predictors of ED visits. Stratified analyses according to sex and age showed that PUD/GERD and dyslipidemia were significant predictors of ED visits in female patients.
Conclusions: This study identified independent predictors of ED visits in HHC patients. Our results provide an important reference for the early prevention, recognition, and adjustment of care plans for at-risk patients. Further studies recruiting more patients and external validation are warranted.
Studying the Water Vapour Variability over the Tropical Indian Ocean using the on-board Microwave Radiometer of Satellite Altimetry
Authors: Nurzaman Fathin , Wijaya Dudy D. , Putri Nabila S. E. , Abdullah N. N. , Bramanto Bryan , Tanuwijaya Zamzam A. J. , Kuntjoro Wedyanto , Setyadji Bambang , Pradipta Dhota 
Published: December 2022

Abstract
The utilization of the altimetric satellite’s on-board radiometer for atmospheric observation is demonstrated. This study uses the Wet Tropospheric Correction (WTC) data from the Topex/Jason altimetry mission series (Topex/Poseidon, Jason-1, Jason-2/OSTM, and Jason-3). The data spans nearly 30 years, making them sufficient for climate study. Precipitable Water Vapor (PWV) is derived from the WTC and used to study the water vapor variability over the Tropical Indian Ocean (TIO). Standard EOF (Empirical Orthogonal Function) analysis on the derived PWV anomaly (PWVA) in the TIO generates two leading modes. The first mode has a dipole spatial structure that explains 18.3% of the total variance, and the second one has a basin-wide homogeneous structure that explains 12.3% of the total variance. Correlation analysis with IOD and ENSO monitoring indices has shown that these two modes are associated with the two interannual variabilities. Further analyses using composite techniques are done to distinguish the different of mechanism and impact between the two. A new monitoring index is proposed here which uses the altimetry-derived PWV anomaly data. The index is computed from the difference of PWV anomaly between the dipole regions in TIO, which effectively describes the activity of the Indian Ocean Walker Circulation (IOWC). This research showcased the feasibility of using the data measured by the radiometer of altimetric satellites for atmospheric studies, a potential continuation of this research would be the use of the synchronous altimeter-radiometer measurement for more advanced analysis such as the ocean-atmosphere coupling.
Student-Led Medical Education Podcast Improves Academic Preparedness, Increases Sense of Belonging, and Enhances Wellness
Authors: Holloway Rachel M. , Yoder Mason C. , Milligan Kevin J. , Daulton Robert S. , Schlaudecker Jeffrey D. 
Published: December 2022

Abstract
Introduction

In the past decade, podcasting has become an increasingly utilized form of asynchronous education amongst medical trainees. Medical education podcasts increase accessibility of novel literature, provide entertainment and promote community. Data on the impact of medical student-run podcasts is limited. The UnsCripted Medicine Podcast (UMP) is a medical student-run podcast created to provide near-peer support, promote academic success, and strengthen sense of belongingness. This study examined UMP listener self-reported behaviors, enjoyability, and podcast efficacy as a comradery-building tool.

Methods

A voluntary, seventeen-question survey was disseminated to all medical students at the University of Cincinnati College of Medicine. The survey utilized Likert scale items, multiple choice, multiple answer and open-ended formats. Descriptive statistics were used for analysis.

Results

143 (n = 19.5%) responses were received. Most respondents had listened to either 3–5 or 5–10 episodes (n = 51 or 41.8% and n = 36 or 29.5%, respectively). Most listeners consumed curriculum-related episodes (n = 109, 89.3%). 96% (n = 96 of 100) of listeners reported an increased sense of preparedness for courses, and 76.8% (n = 76 of 99) of listeners reported reduced stress. The UMP was considered enjoyable (n = 112 of 116, 96.5%) and was associated with an increased sense of belonging within the medical school community (n = 68 of 116, 58.6%).

Discussion

Medical student-run podcasts provide novel opportunities to increase near-peer mentorship within undergraduate medical education. They show promise in decreasing stress, increasing preparedness and increasing sense of belonging. Given the increasing popularity of podcasting in medical education, student podcast initiatives should be supported by medical schools.
An Approach Based on Deep Learning for Recognizing Emotion, Gender and Age
Authors: Nippon Nippon Datta , Juel Juel Sikder 
Published: December 2022

Abstract
At the same time, recognizing the emotions, gender and age of a person is a vital issue in real life. This research focuses on identifying the emotions along with age and gender of different ages male, female, common gender and children. In this study, a modified convolutional neural network (M-CNN) has been proposed for feature extraction where classification is followed by a Multi Support Vector Machine (M-SVM). Instead of detecting the face, a head-detecting technique is also used in the prediction part. To detect the head we proposed a system using the You Only Look Once Version 3 (YOLOV3) network. It helps to extract the feature from the whole head instead of the only face. Three datasets named AR-2022, FER-2022 and GR-2022 are introduced in this study. We also include the common gender in our datasets. In the case of age classification, we categorized the age datasets into 11 categories depending on the similarity of their features, gender into 3 categories and emotions into 7 categories. Our proposed model is compared with other existing models and current research, where the proposed model gives better accuracy and the accuracy of classification of emotions, age and gender are 97.47%, 98.43% and 96.65% respectively.
WITHDRAWN: Non-interference patterns evolving to interference patterns --- variation of Poisson-Arago spot experiment
Authors: peng hui 
Published: December 2022

Abstract

Young’s double slit experiment and Poisson/Arago spot experiment revived the wave theory of the light. The standard interpretation is that the light behaves as waves. Feynman called the double slit experiment the only mystery in quantum mechanics. Recently, the photon chamber has been proposed and utilized to study the behavior of photons near the detecting screen. The experiments show that the light, near the screen, behaves as photons propagating along the straight-line trajectories, and the trajectories distribute as waves. Furthermore, the photon chamber experiments show that, within certain macroscopic distance from the double slit, the pattern is non-interference, which indicates that the standard double slit experiments violate the standard wave interpretations. In this article, we show, the first time, that, within certain macroscopic distance from the ring, the pattern is non-interference, and how the non-interference pattern (near the ring) evolving to the interference pattern (far from the ring).
The experiments show: (1) the nature of the patterns is distance-dependent; (2) to certain macroscopic distance from the ring, the light beams behave as particle; (3) when the distance increases, the non-interference pattern evolves to the interference pattern, i.e., the non-wave nature and the wave distribution coexist in the same wave experiment. The experiments: (1) provide novel phenomena/data for further theoretical development of the optics and for understanding the nature of the light.
Efficient flow equations for dissipative systems
Authors: Schmiedinghoff Gary , Uhrig Götz S. 
Published: December 2022

Open quantum systems provide an essential theoretical basis for the
development of novel quantum technologies, since any real quantum system
inevitably interacts with its environment. Lindblad master equations
capture the effect of Markovian environments. Closed quantum systems can
be treated using flow equations with the particle conserving generator.
We generalize this generator to non-Hermitian matrices and open quantum
systems governed by Lindbladians, comparing our results with recently
proposed generators by Rosso et al. (arXiv:2007.12044). In comparison,
we find that our advocated generator provides an efficient flow with
good accuracy in spite of truncations.
Factors influencing economic benefit of rainwater harvesting: an empirical analysis
Authors: Islam M. Rafiqul 
Published: December 2022

Abstract
This study examines key factors influencing the economic benefit of rainwater harvesting on the household at the Mongla Upazila in the Bagerhat district of coastal Bangladesh. The household survey questionnaire was used to collect primary data from 1040 households. The Ordinary Least Square (OLS) regression analysis was applied to understand the relationship between economic benefit and factors that can affect economic benefit in the household. The empirical result shows that income (1.103**), storage capacity (0.574***), water price (32708.9***), age of rainwater harvesting (100.083***), and total cost (1.627***) positively impact economic benefit while the number of children (35.531**) has a negative relationship. The finding confirms the validity of statistical hypotheses. In addition, heterogeneity analysis was employed to test the model's strength and robustness check to validate the structural function and efficiency of the regression model. The finding concludes with policy recommendations, especially for rain-intensive countries that focus on (i) formulating and implementing rainwater harvesting policy; (ii) integrating rainwater harvesting as a tool for poverty reduction and achieving sustainable development goals; (iii) minimizing mismanagement of (rain) water that causes floods; (iv) initiating programmes and taking the necessary steps for providing financial and non-financial incentives for rainwater harvesting in commercial, and non-commercial buildings.
Enhanced ammonium removal from aquatic systems by a novel copolymer
Authors: Taha Hazem F. , Gad Waseem Ahmed , El-Hussein Ibrahim 
Published: December 2022

AbstractA novel copolymer was used as an adsorbent for enhanced ammonium removal in an aqueous system; different ratios of styrene–acrylic acid copolymers were synthesized by random free radical polymerization and followed by a sulfonation of styrene (acrylic acid 25%–sulfonated styrene 75%) copolymer [P(AA25/SS75)] attained the highest ammonium adsorption capacity (55.8 mg/g) due to the electrostatic attraction between positively charged NH4+ and negatively charged –COO− and –SO3- groups. FTIR spectra for sulfonated polymers illustrated the appearance of characteristic peaks at 100–1200 cm−1 indicating that the copolymers were successfully sulfonated. The influence of different experimental factors (i.e., contact time, pH, NH4+ concentration, adsorbent dose) on ammonium ion adsorption was investigated; three adsorption isotherm models including Langmuir, Freundlich, and Temkin were used to study the adsorption mechanism. The results indicated that the equilibrium of adsorption can be reached within 30 min; the highest adsorption capacity can be achieved around pH 7. Furthermore, Freundlich isotherm was the most suitable for fitting the experimental data which might expose the heterogeneity of the adsorbent surface. The regeneration and reusability studies were also implemented, and results showed that P(AA25/PSS75) was stable and regenerable using (1 M) sulfuric acid as a desorbing agent over five cycles.
Socio-Demographic Association with Knowledge, Attitude and Practice (Kap) Towards Covid-19 Vaccines: A Young Population Cross Sectional Study in Lebanon
Authors: Sakr Samer , Al Khatib Ali , BouRaad Roland , Karaki Nadine , El Said Hassan , Sheet Imtithal , Hamam Bassam 
Published: December 2022

Background:
Since its first emergence in Wuhan-China in the late 2019 to date, the coronavirus disease 2019 (COVID-19) has become the biggest public health threat on an international scale. Vaccination remains the first line of defence against the widespread of the virus.

Objective:
We aim to assess the socio-demographic association with knowledge, attitude and practice (KAP) towards the different COVID-19 vaccines in young Lebanese population.

Method:
This cross-sectional study conducted in Lebanon between January 24th and 31st 2021. 1350 respondents answered this questionnaire. Questions included four dimensions (11 Socio-demographic characteristics, 22 knowledge questions, 5 attitude questions and 5 related to the practices). One-way ANOVA was used to analyse the differences between the KAP variables with the socio-demographic variables. When significant differences were found (p-value < 0.05), Duncan’s Multiple Range test was applied to determine the significant differences between the means.

Results:
The average knowledge about COVID-19 vaccines among our participants is 52.88%; 52.81% showed a good attitude towards the different type of vaccines, and 53.98% demonstrated good practices. The socio-demographic variables having a significant influence on the knowledge and practices towards the COVID-19 vaccines were the living place, the educational level, the school in which the students belong to, the type of job (health-related or non-health related job) and the income range. The type of insurance that respondents have was significantly associated with practices but not with knowledge.

Conclusion
This study showed significant differences in KAP among Lebanese people regarding COVID-19 vaccines, mainly affected by gender, education, work field and income. Our findings reflect fair knowledge, positive attitudes and good practices towards COVID-19 vaccine among the Lebanese population. Consequently, the Ministry of public health must work harder to disseminate, in higher frequency, more accurate information about the vaccines, and organize more vaccination campaigns in order to increase trust in the vaccines efficacy and to decrease the public hesitation.
The efficacy and safety of GP40081 (insulin aspart biphasic 30) compared with NovoMix
®
30 in Type 2 diabetes patients
Authors: Drai Roman V , Mayorov Alexander Y , Karonova Tatiana L , Parfenova Tatiana M , Makarenko Igor E , Magruk Maxim A , Alpenidze Diana N , Kovalik Vladislav V , Zinnatulina Bella R , Grigorjeva Irina V , Andreeva Alena T 
Published: December 2022

Aim:
To evaluate the safety and efficacy of insulin Aspart-Mix biosimilar candidate GP40081 (GP-Asp30) compared with NovoMix
®
30 (NN-Asp30).
Materials & methods:
In a randomized open-label, active-controlled, 26-week non-inferiority clinical trial 264 patients with Type 2 diabetes mellitus were randomized 1:1 to receive once-daily GP-Asp30 or NN-Asp30. The primary safety end point was the immune response rate. Efficacy outcomes were a mean change in HbA1c (primary), frequency of achieving a glycemic g fasting plasma glucose levels, 7-point glucose profiles, and insulin doses.
Results:
The immune response developed in 10/126 (8%) participants in the GP-Asp30 group and in 10/125 (8%) participants in the NN-Asp30 group (p = 1.000). The mean difference in HbA1c change between groups was 0.12 (95%CI [-0.14, 0.38]). Other secondary efficacy and safety outcomes weren't statistically different between the two groups.
Conclusion:
GP-Asp30 demonstrated similar safety and efficacy compared with NN-Asp30 and may be considered a biosimilar insulin.
Retinopathy During the First 5 Years of Type 1 Diabetes and Subsequent Risk of Advanced Retinopathy
Authors: Malone John I. , Gao Xiaoyu , Lorenzi Gayle M. , Raskin Philip , White Neil H. , Hainsworth Dean P. , Das Arup , Tamborlane William , Wallia Amisha , Aiello Lloyd P. , Bebu Ionut ,   on behalf of The Diabetes Control and Complications Trial (DCCT)-Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group
Published: December 2022

OBJECTIVETo determine whether individuals with type 1 diabetes (T1D) who develop any retinopathy at any time prior to 5 years of diabetes duration have an increased subsequent risk for further progression of retinopathy or onset of proliferative diabetic retinopathy (PDR), clinically significant macular edema (CSME), diabetes-related retinal photocoagulation, or anti-vascular endothelial growth factor injections. Additionally, to determine the influence of HbA1c and other risk factors in these individuals.RESEARCH DESIGN AND METHODSDiabetic retinopathy (DR) was assessed longitudinally using standardized stereoscopic seven-field fundus photography at time intervals of 6 months to 4 years. Early-onset DR (EDR) was defined as onset prior to 5 years of T1D duration. Cox models assessed the associations of EDR with subsequent risk of outcomes.RESULTSIn unadjusted models, individuals with EDR (n = 484) had an increased subsequent risk of PDR (hazard ratio [HR] 1.51 [95% CI 1.12, 2.02], P = 0.006), CSME (HR 1.44 [1.10, 1.88], P = 0.008), and diabetes-related retinal photocoagulation (HR 1.48 [1.12, 1.96], P = 0.006) compared with individuals without EDR (n = 369). These associations remained significant when adjusted for HbA1c, but only the association with PDR remained significant after adjustment for age, duration of T1D, HbA1c, sex, systolic/diastolic blood pressure, pulse, use of ACE inhibitors, albumin excretion rate, and estimated glomerular filtration rate (HR 1.47 [95% CI 1.04, 2.06], P = 0.028).CONCLUSIONSThese data suggest that individuals with any sign of retinopathy within the first 5 years of T1D onset may be at higher risk of long-term development of advanced DR, especially PDR. Identification of early-onset DR may influence prognosis and help guide therapeutic management to reduce the risk of future visual loss in these individuals.
Thermodynamic Morphological Study of Liquid Crystalline Compounds
Authors: Srinivas Parashiva Murthy , Mahadeva Jade Madegowda , Hemalatha Kapanigowda , Nandaprakash Mysore Basavaraju , Somashekar Rudrappa 
Published: December 2022

Thermodynamic morphism study has been envisaged using search procedure of phase space of polymorphs at a prescribed temperature and pressure(NPT) of several azoxybenzenes based liquid crystalline compounds at room temperature using molecular structure, unit cell information and AMOEBA parameters employing Force Field computation (FFX) calculations. These calculations were carried out at various intermolecular strengths to understand the morphological walk of molecules with corresponding changes in free energy, change in a force field with a strength of the interactions and free energy difference between successive interaction strengths. This study will help us to understand the nature, range and type of mesophase in a series of azoxybenzene compounds.