bluuebunny/crossref_metadata_2025_split huggingface dataset:
Different phylotypes of Cutibacterium acnes cause different modic changes in intervertebral disc degeneration
Authors: Lan Weibin , Wang Xiaomeng , Tu Xuezhao , Hu Xiunian , Lu Haichuan 
Published: July 2022

Background
The contribution of Cutibacterium acnes (C. acnes) infection to intervertebral disc degeneration (IDD) and the antibiotic therapy has evoked several controversies in recent years. While some microbiology studies report bacterial disc infection within IDD patients, others attribute the positive results to contamination during prolonged cultures. In addition to the clinical controversy, little was known about the mechanism of C. acnes-caused Modic changes (MCs) if C. acnes was the pathogenic factor.

Objectives
This study aimed to investigate the inflammatory mechanism of MCs induced by different phylotypes of C. acnes in patients with IDD.

Methods
Specimens from sixty patients undergoing microdiscectomy for disc herniation were included, C. acnes were identified by anaerobic culture, followed by biochemical and PCR-based methods. The identified species of C. acnes were respectively inoculated into the intervertebral discs of rabbits. MRI and histological change were observed. Additionally, we detected MMP expression in the rabbit model using reverse transcription-quantitative polymerase chain reaction (RT-qPCR).

Results
Of the 60 cases, 18 (30%) specimens were positive for C. acnes, and we identified 4 of 6 defined phylogroups: IA, IB, II and III. The rabbits that received Type IB or II strains of C. acnes showed significantly decreased T1WI and higher T2WI at eighth weeks, while strain III C. acnes resulted in hypointense signals on both T1WI and T2WI. Histological examination results showed that all of the three types of C. acnes could cause disc degeneration and endplates rupture. Moreover, endplate degeneration induced by type IB or II strains of C. acnes is related with MMP13 expression. Meanwhile, strain III C. acnes might upregulated the level of MMP3.

Conclusion
This study suggested that C. acnes is widespread in herniated disc tissues. Different types of C. acnes could induce different MCs by increasing MMP expression.
Spontaneous Regression of Hepatocellular Carcinoma From Autoinfarction and Implications on Liver Transplantation
Authors: Singh Kevin 
Published: July 2022

ABSTRACT
Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide. Spontaneous regression of HCC due to autoinfarction is rare. This case series describes 2 cases of HCC autoinfarction that affected transplant candidacy: 1 patient previously ineligible because of tumor size and not meeting the Milan criteria became eligible after autoinfarction and tumor shrinkage while the second one was delisted in the view of improved symptoms of chronic liver disease and significant HCC regression. These cases provide an opportunity to review the pathogenesis of HCC autoinfarction and to remind practitioners of how this entity might alter decision-making around transplant eligibility.
The Effect of Initial Intensity of Light Sources on the Fraunhofer Diffraction Pattern for Circular Apperture Using the Gauss-Legendre 4 Point Quadrature Integration Numerical Method: Scientific and Islamic Integration-Interconnection
Authors: Yanuarief Cecilia 
Published: July 2022

Visualization of Fraunhofer diffraction pattern of circular apperture has been obtained using the 4 point Gauss-Legendre Quadrature integration method. The 4 point Gauss-Legendre quadrature integration method is used to solve the integral function of intensity. The intensity function is used to display the intensity distribution of the Fraunhofer diffraction pattern of circular apperture in a visual form through a computer programming simulation based on GUI (Graphycal User Interface) MATLAB. Simulation results show changes in initial intensity affect diffraction patterns.
Study of hsa_circRNA_000121 and hsa_circRNA_004183 in papillary thyroid microcarcinoma
Authors: Bai Chao , Yang Wenwen , Ouyang Ru , Li Zongbao , Zhang Li 
Published: July 2022

Abstract
We detected the expressions of hsa_circRNA_000121 and hsa_circRNA_ 004183 in papillary thyroid microcarcinoma (PTMC) and explored their relationship with the invasiveness of PTMC. PTMC patients with (n = 30; metastasis group) and without lymph node metastasis (n = 30; nonmetastasis group) were included. The levels of hsa_circRNA_000121, hsa_circRNA_004183, hsa-miR-4763, hsa-miR-6775, sarcoma gene (SRC), and MMP-14 were detected with real-time polymerase chain reaction. Receiver-operating characteristic (ROC) analyzed the diagnostic value of hsa_circRNA_000121 and hsa_circRNA_004183. Binary logistic regression analysis evaluated the relationship of gene expression with PTMC invasiveness. In PTMC tissue samples, compared with the metastasis group, the expression of hsa_circRNA_000121, hsa_circRNA_004183, SRC, and MMP-14 in the nonmetastasis group decreased, while the expression of hsa-miR-4763 and hsa-miR-6775 increased. In peripheral blood, compared with the metastasis group, the expression of hsa_circ_000121 and hsa_circRNA_004183 in the nonmetastasis group decreased. Both hsa_circRNA_000121 and hsa_circRNA_004183 had good sensitivity and specificity for diagnosing PTMC lymph node metastasis, with a cut-off value of 0.796 and 0.938, respectively. However, the gene expressions were not significantly associated with PTMC lymph node metastasis. Hsa_circRNA_000121 may upregulate SRC expression through hsa-miR-4763, while hsa_circRNA 000121 may upregulate MMP-14 expression through hsa-miR-6775, thereby promoting the aggressiveness of PTMC and ultimately leading to cervical lymph node metastasis. hsa_circRNA_000121 and hsa_circRNA_004183 may become potential biomarkers of PTMC aggressiveness.
Texturing of nanocoatings for surface acoustic wave-based sensors for volatile organic compounds
Authors: Aleksandrova Mariya 
Published: July 2022

Abstract
An approach for texturing of gas-sensitive nanocoatings by using surface acoustic waves (SAW) is presented in this article. The objective of the work is to enhance the performance of precise SAW-based gas sensors due to the increased specific area of the sensitive nanocoating, induced during its growth and to replace the expensive lithographic techniques for nanopatterning, typically used for this purpose. The technique can be used for tuneable alignment of nanoparticles or nanowires and it is scale-independent. To control the texture of the sensitive nanocoating, a specific electrode topology was used to generate waves with a specific space distribution, which in turn caused assembling of the nanoparticles increasing the adsorption capacity. In this way, a broader dynamic range of 7,000 ppm was achieved (three times extended as compared to the non-textured sensing film), measurement error of 0.6% against 4% for the non-patterned, faster response time in the sub-seconds range (970 ms vs 1.1 s), negligible hysteresis of 10 mV (against >100 mV), and very good sensitivity of 5 µV per ppm, which are in line with the current standards for ethanol sensors. The enhanced sensor parameters were achieved by implementation of conventional patterning technologies without the need for nanolithographic techniques for the texturing the nanocoating. The method is low-cost, and applicable in a variety of sensing structures despite the sensing coating (optical, biological, etc.).
Language proficiency: from description to prescription and back?
Authors: Leung Constant 
Published: July 2022

Abstract
Language proficiency, when expressed as a grade or a mark, is often associated with the notions of measurement accuracy, reliability and trustworthiness. In this article my focus is on English as an additional/second language proficiency in the past fifty years or so. I will suggest that the notion of proficiency is an artefact influenced by the ebbs and flows of intellectual movements and conceptual recontextualizations. The onset of the concept of communicative competence in the 1970s serves as the point of departure for this discussion. I will explore the ways in which this primarily research-oriented concept has been filtered through a particular set of disciplinary and ideological perspectives that led to a pared-down view of language communication and a universalist approach to curriculum development and assessment of proficiency. After that I will turn to the recent research findings and theorizations in fields such as academic literacies, English as a Lingua Franca, flexible multilingualism and translanguaging to show the need for a more empirically situated, dynamic and fluid approach to language use and language proficiency. Further exploratory work is needed at this watershed moment. I will illustrate some of the challenges by analysing some of the conceptual and technical difficulties found in an international language curriculum and assessment framework as it attempts to embody a more dynamic and situated approach. In the final part of the discussion I will suggest a set of basic questions for further reflexive analysis and research.
Altindische Weisheit in Byzanz: Zu den didaktischen Erzählstrategien in Symeon Seths
Stephanites und Ichnelates
und seinen arabischen Vorgängern
Authors: Hölzlhammer Lilli 
Published: July 2022

Zusammenfassung
Der Artikel bemüht sich, das Gelehrteninteresse nachzuvollziehen, das für die Übersetzung der arabischen Pañcatantra Version in das byzantinische Stephanites kai Ichnelates verantwortlich ist. Dafür soll ein kurzer Vergleich zwischen der byzantinischen und den arabischen Editionen unternommen werden, um deren große Unterschiede zu verdeutlichen und, wo möglich, zu erklären. Im Anschluss wird durch eine exemplarische Analyse der ersten beiden Bücher des griechischen Texts der Fokus auf seine didaktisch-narrativen Strukturen gelegt. Auf diese Weise wird deutlich, wie die narrative Komplexität des Textes ihm seine Fähigkeit verleiht, das Wissen und die Wertvorstellungen anderer Kulturen zu absorbieren.
Miniaturised ultra-wideband rectangular shaped slot antenna for ground penetrating radar applications
Authors: Pande Jyotirmay , Singh Ankita , Gupta Avni , Singh Kuldeep , Sharma Ankit 
Published: July 2022

Abstract
In the proposed work, a miniaturised ultra-wideband tapered slot planar antenna with the aim of gain enhancement, working bandwidth containing lower frequency range, and improving antenna efficiency is presented. The proposed antenna consists of a slotted patch printed on the top layer of FR4 substrate with three 50-Ω resistors connected in the slotted arms and bottom layer consists of an optimized ground plane with a non-uniform parasitic patch which is used to achieve circular polarization in the frequency range of 2.4–2.6 GHz. The measured impedance bandwidth of the proposed antenna is 0.3–4 GHz with a peak gain of 3.2 dBi. The overall antenna efficiency is 83% and radiation patterns of the proposed design on different frequencies are shown to confirm the proposed antenna result, especially at lower frequencies. The proposed antenna can be used for the detection of artifacts in the deeper ground known as ground-penetrating radar applications.
Protective role ofSpirulina platensisliquid extract against salinity stress effects onTriticum aestivumL.
Authors: Hamouda Ragaa A. , Shehawy Mayada A. , Mohy El Din Soad M. , Albalwe Fauzeya Mateq , Albalawi Hessa Meteq R. , Hussein Mervat H. 
Published: July 2022

AbstractSalt stress is one of the most serious factors that influence the plant growth and yield. The extensive use of chemical fertilizers caused an increase in land contamination and hence effects on human health. The use of biofertilizers can solve these problems. In the present work, different concentrations ofSpirulina platensisliquid extracts (SLEs; 1%, 2%, and 4%) were used to enhance seeds germination, seedling growth, length of radical, number of leaves, and plant height ofT. aestivumL.S. platensisliquid extract (SLE) 2% was chosen to test against salt stress with 10% and 25% seawater inT. aestivumL. watered. The growth parameters such as shoot, root, length, fresh, dry weight, leaf width, number, and area were used to estimate the effects of 2% SLE against salt stress caused by seawater. Also the carbohydrate, protein, phenol, and total antioxidant contents were measured inT. aestivumL. treated with 2% SLE in combination with seawater and watered with different concentrations with seawater alone. The results denote that the best concentration of SLEs was 2%, which promoted the germination growth ofT. aestivumL. in comparison to control and other concentrations. SLE (2%) enhanced the carbohydrates, protein, total phenol contents, and antioxidant contents ofT. aestivumL., treated with seawaters (SW10% and SW25%) and SLEs in comparison toT. aestivumL. SW 10% and 25% alone.S. platensisliquid extract (SLE) can be used as biofertilizer to enhance the growth and phytochemical contents ofT. aestivumL. and to make tolerance ofT. aestivumL. against salinity.
Hi, Mom: Farewell in the Vision and Reconciliation in the Farewell
Authors: Zhang Ali 
Published: July 2022

Abstract

Hi, Mom (Nihao, Li Huanying 2021) is the first film directed by Jia Ling, a comedian. An autobiographical movie, it develops a mom–daughter-reuniting visional field in the mode of a time-travelling film. In fantasy scenes set in the 1980s, the film reshapes the “mother–daughter” emotional logic with that of “sisterhood”, using comic effects created by misplaced identities to reveal the tragic crux of the cruel reality of “forever losing maternal love”. “The art of analyzing emotions” is pursued through “interpreting visions”. The protagonist ultimately reconciles with reality not by controlling the vision rationally and subjectively, but by creating a deeper vision—a “true fairy tale”. This is for the purpose of retaining a scene of imagined realization of desire: bidding a fond farewell to mom in the vision, fulfilling a wish in the farewell and reconciling with reality and ego in the visional “mutual reconciliation”.
Energy absorption behaviors of designed metallic square tubes under axial loading: Experiment-based benchmarking and finite element calculation
Authors: Ridwan Ridwan , Nuriana Wahidin , Prabowo Aditya Rio 
Published: July 2022

Abstract
In this article, the load resistance and energy absorptions of thin-walled structures on the square tube were numerically evaluated by the finite element method. This structure can be widely used in automotive industries, industrial buildings, ships, offshore platforms, and airplanes. In the finite element method, thin-walled structures on square tubes were examined with different wall thicknesses and materials. The materials used are mild steel, SAE 1045 steel, and SAE 1008 steel. Using the numerical results, the thickness of the wall influences the strength of the structure. Moreover, SAE 1045 steel material also seems to increase the strength of the tube under axial loading compared to the mild steel and SAE 1008 steel material. It is also important to remember that the finite element solution depends on defining your mesh size and boundary conditions. The mesh size is also compared and assessed.
Immunopterin: A prospective therapy and preventative to fight COVID-19?
Authors: Moheno Phillip B. B. , Fuchs Dietmar 
Published: July 2022

Abstract

Background
The authors explore the therapeutic and prophylactic efficacies of Immunopterin (calcium pterin-6-carboxylate chelate) against coronavirus colds and as a therapy against COVID-19.

Methods
To determine Immunopterin’s therapeutic efficacy against colds and flus, a 5-year observational study was conducted with 34 subjects who took Immunopterin when feeling symptoms of a cold or flu. The mean sample cold recovery time was compared to the US population mean. A review of the Moheno (2014) 2-year observational study was conducted to evaluate the prophylactic efficacy of Immunopterin against colds. Early COVID-19 case studies, treated with Immunopterin, were collected to explore Immunopterin’s efficacy as a therapeutic and prophylactic against COVID19 disease.

Results
The mean cold recovery time for the therapeutic sample in the cold/flu observational study was 30 h compared to the US population mean of 168 h (N = 34; p < 0.001). Subjects taking prophylactic Immunopterin reported 0% incidences of colds and flus (N = 31). Immunopterin successfully treated four confirmed COVID-19 subjects. A fifth clinical nurse case study demonstrates COVID-19 prevention.

Conclusions
The therapeutic and prophylactic efficacies of Immunopterin against coronavirus colds, along with reported cross-reactivity between coronavirus colds and SARS-CoV-2 strongly suggest Immunopterin can act as a therapy and preventative against COVID- 19 infection associated disease.
Determining the Optimal Frequency and Perturbation Amplitude for AC Electrical Resistance Measurements of Cement-Based Materials Using Harmonic Analysis
Authors: Dong Zheng , Torbati-Sarraf Hamidreza , Poursaee Amir 
Published: July 2022

Abstract
Measuring electrical resistivity is becoming a desirable method for evaluating the material property in cement-based materials. As a rapid nondestructive technique, measurement of resistivity is frequently performed both in laboratory specimens and on-site structures. Alternating current/potential (AC)-based methods are common approaches to measure the resistivity in cement-based materials. The alternating perturbation amplitudes applied range from several millivolts to even volts. However, how the perturbation amplitude influences the results, and what are the optimal frequency and perturbation amplitude are still in question. In the present study, AC resistance measurements using electrochemical impedance spectroscopy were performed on cement-based specimens with different compositions. To investigate the effect of perturbation amplitude on the measured resistance, different amplitudes of potential perturbation varying from 5 mV up to 1,000 mV were applied. The reliability of data was evaluated by the harmonic analyses. Results indicated that, as the resistivity of specimens increased, a slight decrease in the fR (i.e., the frequency at which the ohmic resistance is measured) was observed. Noticeably, significant scatter in fR was demonstrated by applying different potential perturbations, especially for amplitudes lower than 50 mV. In terms of the perturbation amplitude, the results of resistivity were generally maintained in a relatively small variation when the potential perturbation was higher than 100 mV. Based on harmonic analyses, the appropriate frequency and perturbation amplitude for measuring the resistance of cement-based materials were determined.
The Impact of Sister City Surabaya-Kitakyushu Cooperation on Environmental Development in Surabaya
Authors: Novia Millenia Nur Fitriana  , Ba'adilla Nesya Nur Hakiki  , Cahyo Wisnu Rubiyanto  
Published: July 2022

Surabaya is one of the largest cities in East Java and the Mayor of Surabaya has played an active role in improving infrastructure in recent years to realize a green city or better known as eco-city. This active role is motivated by the status of Surabaya which is classified as the region with the highest environmental pollution in East Java. The purpose of this study is to find out the environmental impact of the Surabaya Green City Plan implemented by the Surabaya City Government and Kitakyushu Shuangcheng. According to the authors of this study, it is interesting because participation in the sister city program between Surabaya and Kitakyushu has had a positive impact on Surabaya's environment. This research uses qualitative methods and gathers reliable sources as research references. To answer the research question, researchers usedgreen polyt ik theory and the concept of twin cities. The results of the study show that surabaya's city governance is now much better with green open space along its path, which makes Surabaya known as one of the best cities for waste management in Indonesia.
Comprehensive nutrient gap analysis of children (6-23 months) of selected villages of jambusar block in Bharuch district
Authors: Gandhi Hemangini , Srivastava Nandani , Thakur Bhumika 
Published: July 2022

The "First 1000 Days" are a period of rapid physical growth and enhanced mental development that provides a once-in-a-lifetime opportunity to create lifelong health and intelligence. These first 1000 days of life prepare a child for good health for the rest of their life. Quality of Complementary food plays very important role in maintaining growth and development of young children. It was a University-NGO collaborative study so the study was conducted in the villages which comes under working of aatapi seva foundation in Jambusar block. In this study Jambusar block was purposively selected and the study was conducted in anganwadi centers of 5 villages where aatapi seva foundation is currently working. Total 232 children were enrolled in the study and data on Socio- economic status (HHs), Practices about Complementary feeding and three day 24 hour Dietary Recall. Nutrient gap analysis for 11 nutrients were carried out using RDA for children given by ICMR 2020The results of the study showed the all of the children had a percent nutritional deficit for all micronutrients. The energy deficit in 1-2 year old children was 48.8%, compared to 13.4% in the 6-12 month age group. Minimum meal frequency, dietary diversity, and acceptable diets were found to be 51 %, 71%, and 34%, respectively. It can be concluded that breast feeding practices and complementary feeding practices needs to be strengthen among young mothers. Energy deficit was seen in all the children. Nutrient gap was found for all the micronutrients in all the children.
Medical research: The flop side
Authors: Mishra Badrinarayan 
Published: July 2022

Science in general and medical and allied sciences, in particular, have undergone a sea of change since its conception. In recent times it is experiencing exponential growth due to vast technological advances in the field of research. While some are on the right track others are in the wrong hands.This editorial explores the latter part, which needs immediate global attention. If corrective measures are not honestly and immediately implemented the end product will brew more trouble than any good for mankind.