bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interaction Between Equatorial to Low‐Latitude Postmidnight F‐Region Irregularities and LSTIDs in China During Geomagnetic Disturbances Based on Ground‐Based Instruments
Authors: Jin Han , Yan Chunxiao , Yang Guotao , Huang Fuqing , Xie Haiyong , Zhao Xiukuan , Sun Wenjie , Li Yaxian , Hozumi Kornyanat , Jiao Jing 
Published: June 2022

AbstractIn this paper, the interaction between equatorial to low‐latitude postmidnight ionospheric irregularities and large‐scale traveling ionospheric disturbances (LSTIDs) on 14 December 2015 during strong geomagnetic disturbances in China is studied by using multiple ground‐based observations. Postmidnight irregularities initiated near the magnetic equator and extended northward to higher latitudes (∼28°N) until the local early morning period (∼05 LT), which is unusual in the Northern Hemisphere winter. Multibeam observations by the very high frequency coherent scatter radar at Fuke (19.5°N, 109.1°E; dip latitude 14.4°N), Hainan Island, China, showed that the meter‐scale field‐aligned irregularities were still in the evolutionary phase during the postmidnight period (∼04 LT) instead of the fossil structures that must already be in their decay phase. Meanwhile, the emergence of the postmidnight ionospheric irregularities was accompanied by the passage of LSTIDs, as revealed by total electron content measurements. Southward and northward LSTIDs, with velocities of ∼550–570 m/s and periods of ∼80–100 min, that originated from opposite hemispheres met at ∼27°–28°N, and the LSTIDs might produce localized perturbation during their passage to initiate the instability for the postmidnight irregularity development. The height of the ionospheric F‐layer measured by the collocated Digisonde at Fuke was suggested to be modulated by the overshielding penetration electric field and storm‐related atmospheric gravity waves (AGWs). This interesting case gives insight into the important role of storm‐related AGWs in providing seeding sources for plasma bubble development and reveals unique characteristics of coupling between LSTIDs and plasma bubbles during the postmidnight sector.
Large‐Scale High‐Speed Jets in Earth's Magnetosheath: Global Hybrid Simulations
Authors: Guo Jin , Lu San , Lu Quanming , Lin Yu , Wang Xueyi , Ren Junyi , Hao Yufei , Huang Kai , Wang Rongsheng , Gao Xinliang 
Published: June 2022

AbstractHigh‐speed jets (HSJs) occur frequently in Earth's magnetosheath downstream of the quasiparallel bow shock. They have great impacts on the magnetosheath and the magnetosphere. Using two‐dimensional global hybrid simulations, we investigate the formation and evolution of HSJs with different solar wind conditions. When the quasi‐parallel shock is formed, HSJs begin to appear in the quasi‐parallel magnetosheath. Some elongated HSJs formed at the quasi‐parallel bow shock extend toward the quasi‐perpendicular magnetosheath along with the background magnetosheath flow. As the elongated HSJs moves in the magnetosheath, filamentary structures of the velocity, ion density, and temperature occur in the magnetosheath. The filamentary structures are the traces of HSJs moving in the magnetosheath. Moreover, the Kelvin‐Helmholtz instability can be excited at HSJs, which causes meandering of HSJs. When the interplanetary magnetic field is aligned to the solar wind velocity, the large‐scale HSJs with a parallel (perpendicular) scale size of about 2.5 RE (0.3 RE) are formed at the magnetosheath where the θBn is approaching zero. Then, some HSJs converge, leading to the formation of even larger HSJs with a parallel (perpendicular) scale size of 5 RE (0.6 RE).
Subducting Indian Lithosphere Controls the Deep Carbon Emission in Lhasa Terrane, Southern Tibet
Authors: Zhao Wenbin , Guo Zhengfu , Zheng Guodong , Pinti Daniele L. , Zhang Maoliang , Li Jujing , Ma Lin 
Published: June 2022

AbstractThe India‐Asia orogenic zone is considered to participate significantly in the Earth's geological carbon budget. However, the carbon cycling process at orogenic belts with ongoing continental subduction is poorly constrained. Here, new He‐C‐N systematics of hydrothermal gases in Lhasa terrane are reported to explore carbon cycling and the role of the subducting Indian slab. Except for samples where the CO2 content and C isotopic signature were modified by calcite precipitation, gas samples in Lhasa terrane display low 3He/4He ratios of 0.015–0.895 RA but with increasing mantle‐helium input from south to north. Our modeling results show that the continuous subduction of the Indian continental slab has caused high Th‐U contents and time‐integrated 4He production rates in the present mantle wedge beneath the Lhasa terrane. The N‐S helium isotopic trend can be interpreted as a northward‐decreasing mantle enrichment. Compared to volatiles showing crustal helium but mantle‐like δ13C ratios, mantle‐helium‐richer fluids display heavier δ13C ratios, higher CO2/3He and molar C/N values, indicating a substantial carbonate input. We propose that the heavier carbon isotopes are inherited from the carbonated‐enriched mantle (CEM) rather than the carbonate assimilation of the overlying continental crust. Combined with an eastward increase in dip angle of the Indian lithosphere, we suggest that the slab rollback has caused asthenosphere heat flow and consequent decarbonation in CEM beneath northern and eastern Lhasa terrane, leading to enhanced isotopically heavier carbon release. Our study highlights the controlling role of subducting Indian lithosphere on the regional distribution of volatiles in the Lhasa terrane.
A New Parameterization of Coastal Drag to Simulate Landfast Ice in Deep Marginal Seas in the Arctic
Authors: Liu Yuqing , Losch Martin , Hutter Nils , Mu Longjiang 
Published: June 2022

AbstractLandfast ice is nearly immobile sea ice attached to the coast. Landfast ice inhibits atmosphere‐ocean fluxes of heat, moisture, and momentum, leads to offshore flaw polynyas, and stores fresh river water in wintertime. Despite these important roles in coastal environments, landfast ice is not well simulated in current sea ice models, because landfast ice dynamics differ from the pack ice in the interior Arctic and require explicit parameterization. The dynamical mechanisms for landfast ice formation are linked to the local geography. Grounded ice ridges act as anchor points in shallow water. Coastlines and offshore island chains may also be pinning points between which arches of landfast ice can form in deep water. The grounding mechanism for landfast ice in shallow marginal seas has been successfully parameterized using bathymetry information, but this grounding scheme fails in deep regions. We describe a new landfast ice parameterization that uses lateral drag as a function of sea ice thickness, drift velocity, and local coastline length. The simulated landfast ice in a 36 km pan‐Arctic sea ice‐ocean simulation is compared to observations from satellite data and the effect of the new lateral drag parameterization is evaluated. The combination of the established grounding scheme for shallow water and the new lateral drag parameterization for deep water leads to an improved and realistic landfast ice distribution in most marginal seas in the Arctic. These results suggest that multiple mechanisms are at work to create and maintain landfast ice in marginal seas.
CD147 a direct target of miR-146a supports energy metabolism and promotes tumor growth in ALK+ ALCL
Authors: Montes-Mojarro Ivonne-Aidee , Steinhilber Julia , Griessinger Christoph M. , Rau Achim , Gersmann Ann-Kathrin , Kohlhofer Ursula , Fallier-Becker Petra , Liang Huan-Chang , Hofmann Ute , Haag Mathias , Klapper Wolfram , Schaeffeler Elke , Pichler Bernd J. , Schwab Matthias , Fend Falko , Bonzheim Irina , Quintanilla-Martinez Leticia 
Published: June 2022

AbstractWe recently reported that miR-146a is differentially expressed in ALK+ and ALK− anaplastic large cell lymphoma (ALCL). In this study, the downstream targets of miR-146a in ALK+ ALCL were investigated by transcriptome analysis, identifying CD147 as potential target gene. Because CD147 is differentially expressed in ALK+ ALCL versus ALK− ALCL and normal T cells, this gene emerged as a strong candidate for the pathogenesis of this tumor. Here we demonstrate that CD147 is a direct target of miR-146 and contributes to the survival and proliferation of ALK+ ALCL cells in vitro and to the engraftment and tumor growth in vivo in an ALK+ ALCL-xenotransplant mouse model. CD147 knockdown in ALK+ ALCL cells resulted in loss of monocarboxylate transporter 1 (MCT1) expression, reduced glucose consumption and tumor growth retardation, as demonstrated by [18F]FDG-PET/MRI analysis. Investigation of metabolism in vitro and in vivo supported these findings, revealing reduced aerobic glycolysis and increased basal respiration in CD147 knockdown. In conclusion, our findings indicate that CD147 is of vital importance for ALK+ ALCL to maintain the high energy demand of rapid cell proliferation, promoting lactate export, and tumor growth. Furthermore, CD147 has the potential to serve as a novel therapeutic target in ALK+ ALCL, and warrants further investigation.
Eruption of ultralow-viscosity basanite magma at Cumbre Vieja, La Palma, Canary Islands
Authors: Castro Jonathan M. , Feisel Yves 
Published: June 2022

AbstractThe viscosity of magma exerts control on all aspects of its migration through the crust to eruption. This was particularly true for the 2021 eruption of Cumbre Vieja (La Palma), which produced exceptionally fast and fluid lava at high discharge rates. We have performed concentric cylinder experiments to determine the effective viscosities of the Cumbre Vieja magma, while accounting for its chemistry, crystallinity, and temperature. Here we show that this event produced a nepheline-normative basanite with the lowest viscosity of historical basaltic eruptions, exhibiting values of less than 10 to about 160 Pa s within eruption temperatures of ~1200 to ~1150 °C. The magma’s low viscosity was responsible for many eruptive phenomena that lead to particularly impactful events, including high-Reynolds number turbulent flow and supercritical states. Increases in viscosity due to crystallization-induced melt differentiation were subdued in this eruption, due in part to subtle degrees of silica enrichment in alkaline magma.
Signature of Kondo hybridisation with an orbital-selective Mott phase in 4d Ca2−xSrxRuO4
Authors: Kim Minsoo , Kwon Junyoung , Kim Choong H. , Kim Younsik , Chung Daun , Ryu Hanyoung , Jung Jongkeun , Kim Beom Seo , Song Dongjoon , Denlinger Jonathan D. , Han Moonsup , Yoshida Yoshiyuki , Mizokawa Takashi , Kyung Wonshik , Kim Changyoung 
Published: June 2022

AbstractThe heavy fermion state with Kondo-hybridisation (KH), usually manifested in f-electron systems with lanthanide or actinide elements, was recently discovered in several 3d transition metal compounds without f-electrons. However, KH has not yet been observed in 4d/5d transition metal compounds, since more extended 4d/5d orbitals do not usually form flat bands that supply localised electrons appropriate for Kondo pairing. Here, we report a substitution- and temperature-dependent angle-resolved photoemission study on 4d Ca2−xSrxRuO4, which shows the signature of KH. We observed a spectral weight transfer in the γ-band, reminiscent of an orbital-selective Mott phase (OSMP). The Mott localised γ-band induces the KH with an itinerant β-band, resulting in spectral weight suppression around the Fermi level. Our work demonstrates the evolution of the OSMP with possible KH among 4d electrons, and thereby expands the material boundary of Kondo physics to 4d multi-orbital systems.
Reading and writing habits compensate for aging effects in speech connectedness
Authors: Malcorra Bárbara L. C. , Mota Natália B. , Weissheimer Janaina , Schilling Lucas P. , Wilson Maximiliano A. , Hübner Lilian C. 
Published: June 2022

AbstractWe investigate the association of short- and long-range recurrences (speech connectedness) with age, education, and reading and writing habits (RWH) in typical aging using an oral narrative production task. Oral narrative transcriptions were represented as word-graphs to measure short- and long-range recurrences. Speech connectedness was explained by the combination of age, education, and RWH, and the strength of RWH’s coefficient reflects the aging effect.
A 10-hour within-participant magnetoencephalography narrative dataset to test models of language comprehension
Authors: Armeni Kristijan , Güçlü Umut , van Gerven Marcel , Schoffelen Jan-Mathijs 
Published: June 2022

AbstractRecently, cognitive neuroscientists have increasingly studied the brain responses to narratives. At the same time, we are witnessing exciting developments in natural language processing where large-scale neural network models can be used to instantiate cognitive hypotheses in narrative processing. Yet, they learn from text alone and we lack ways of incorporating biological constraints during training. To mitigate this gap, we provide a narrative comprehension magnetoencephalography (MEG) data resource that can be used to train neural network models directly on brain data. We recorded from 3 participants, 10 separate recording hour-long sessions each, while they listened to audiobooks in English. After story listening, participants answered short questions about their experience. To minimize head movement, the participants wore MEG-compatible head casts, which immobilized their head position during recording. We report a basic evoked-response analysis showing that the responses accurately localize to primary auditory areas. The responses are robust and conserved across 10 sessions for every participant. We also provide usage notes and briefly outline possible future uses of the resource.
Mobile device-based Bluetooth Low Energy Database for range estimation in indoor environments
Authors: Pascacio Pavel , Torres-Sospedra Joaquín , Jiménez Antonio R. , Casteleyn Sven 
Published: June 2022

AbstractThe demand to enhance distance estimation and location accuracy in a variety of Non-Line-of-Sight (NLOS) indoor environments has boosted investigation into infrastructure-less ranging and collaborative positioning approaches. Unfortunately, capturing the required measurements to support such systems is tedious and time-consuming, as it requires simultaneous measurements using multiple mobile devices, and no such database are available in literature. This article presents a Bluetooth Low Energy (BLE) database, including Received-Signal-Strength (RSS) and Ground-Truth (GT) positions, for indoor positioning and ranging applications, using mobile devices as transmitters and receivers. The database is composed of three subsets: one devoted to the calibration in an indoor scenario; one for ranging and collaborative positioning under Non-Line-of-Sight conditions; and one for ranging and collaborative positioning in real office conditions. As a validation of the dataset, a baseline analysis for data visualization, data filtering and collaborative distance estimation applying a path-loss based on the Levenberg-Marquardt Least Squares Trilateration method are included.
Using the integrative model of behavioural prediction to understand COVID-19 vaccine hesitancy behaviour
Authors: Romate John , Rajkumar Eslavath , Greeshma Rajgopal 
Published: June 2022

AbstractThe officials realized that the vaccination drive alone would not be sufficient, but the individual's response towards getting vaccinated needs to be assessed and addressed, especially in India, where the diverse culture could widely affect the population's vaccination behaviour. The study aimed to identify the predictors of vaccine hesitancy behaviour using the health belief model and theory of planned behaviour and understand mediating and moderating influence of knowledge and social support on the relationship between the predictors and vaccine hesitancy behaviours among the Indian population. Data was collected from 1006 samples. Regression analysis was performed to assess the variances exerted on vaccine hesitancy behaviours. Also, SEM AMOS was employed to examine the mediation and moderation effects of knowledge about vaccines and social support. The findings indicated that around 11% of the respondents were hesitant to get vaccinated. The combined models of HBM and TPB provide high predictive power. The analysis also revealed that knowledge about vaccine significantly mediates partially between a few constructs of HBM and TPB concerning hesitancy. This study provides the theoretical framework and suggests that the health belief model and the theory of planned behaviour model could explain the psychological influences of vaccine hesitancy in India.
Association of protein function-altering variants with cardiometabolic traits: the strong heart study
Authors: Shan Yue , Cole Shelley A. , Haack Karin , Melton Phillip E. , Best Lyle G. , Bizon Christopher , Kobes Sayuko , Köroğlu Çiğdem , Baier Leslie J. , Hanson Robert L. , Sanna Serena , Li Yun , Franceschini Nora 
Published: June 2022

AbstractClinical and biomarker phenotypic associations for carriers of protein function-altering variants may help to elucidate gene function and health effects in populations. We genotyped 1127 Strong Heart Family Study participants for protein function-altering single nucleotide variants (SNV) and indels selected from a low coverage whole exome sequencing of American Indians. We tested the association of each SNV/indel with 35 cardiometabolic traits. Among 1206 variants (average minor allele count = 20, range of 1 to 1064), ~ 43% were not present in publicly available repositories. We identified seven SNV-trait significant associations including a missense SNV at ABCA10 (rs779392624, p = 8 × 10–9) associated with fasting triglycerides, which gene product is involved in macrophage lipid homeostasis. Among non-diabetic individuals, missense SNVs at four genes were associated with fasting insulin adjusted for BMI (PHIL, chr6:79,650,711, p = 2.1 × 10–6; TRPM3, rs760461668, p = 5 × 10–8; SPTY2D1, rs756851199, p = 1.6 × 10–8; and TSPO, rs566547284, p = 2.4 × 10–6). PHIL encoded protein is involved in pancreatic β-cell proliferation and survival, and TRPM3 protein mediates calcium signaling in pancreatic β-cells in response to glucose. A genetic risk score combining increasing insulin risk alleles of these four genes was associated with 53% (95% confidence interval 1.09, 2.15) increased odds of incident diabetes and 83% (95% confidence interval 1.35, 2.48) increased odds of impaired fasting glucose at follow-up. Our study uncovered novel gene-trait associations through the study of protein-coding variants and demonstrates the advantages of association screenings targeting diverse and high-risk populations to study variants absent in publicly available repositories.
Chemical effects induced by the mechanical processing of granite powder
Authors: Sanna Anna Laura , Carta Maria , Pia Giorgio , Garroni Sebastiano , Porcheddu Andrea , Delogu Francesco 
Published: June 2022

AbstractStarting from 1970s, the use of mechanical forces to induce chemical transformations has radically changed vast areas of metallurgy and materials science. More recently, mechanochemistry has expanded to core sectors of chemistry, showing the promise to deeply innovate chemical industry while enhancing its sustainability and competitiveness. We are still far, however, from unveiling the full potential of mechanical activation. This study marks a step forward in this direction focusing on the chemical effects induced on the surrounding gaseous phase by the mechanical processing of granite. We show that fracturing granite blocks in oxygen can result in the generation of ozone. The refinement of coarse granite particles and the friction between fine ones are also effective in this regard. Combining experimental evidence related to the crushing of large granite samples by uniaxial compression and the ball milling of coarse and fine granite powders, we develop a model that relates mechanochemical ozone generation to the surface area effectively affected by fracture and frictional events taking place during individual impacts. We also extend the investigation to gaseous phases involving methane, oxygen, benzene and water, revealing that chemical transformations occur as well.
Genome-wide specificity of plant genome editing by both CRISPR–Cas9 and TALEN
Authors: Bessoltane Nadia , Charlot Florence , Guyon-Debast Anouchka , Charif Delphine , Mara Kostlend , Collonnier Cécile , Perroud Pierre-François , Tepfer Mark , Nogué Fabien 
Published: June 2022

AbstractCRISPR and TALENs are efficient systems for gene editing in many organisms including plants. In many cases the CRISPR–Cas or TALEN modules are expressed in the plant cell only transiently. Theoretically, transient expression of the editing modules should limit unexpected effects compared to stable transformation. However, very few studies have measured the off-target and unpredicted effects of editing strategies on the plant genome, and none of them have compared these two major editing systems. We conducted, inPhyscomitrium patens, a comprehensive genome-wide investigation of off-target mutations using either a CRISPR–Cas9 or a TALEN strategy. We observed a similar number of differences for the two editing strategies compared to control non-transfected plants, with an average of 8.25 SNVs and 19.5 InDels for the CRISPR-edited plants, and an average of 17.5 SNVs and 32 InDels for the TALEN-edited plants. Interestingly, a comparable number of SNVs and InDels could be detected in the PEG-treated control plants. This shows that except for the on-target modifications, the gene editing tools used in this study did not show a significant off-target activity nor unpredicted effects on the genome, and did not lead to transgene integration. The PEG treatment, a well-established biotechnological method, in itself, was the main source of mutations found in the edited plants.
Detection of bulk feed volume based on binocular stereo vision
Authors: Liu Zhihai , Dai Zhenrui , Zeng Qingliang , Liu Jinxia , Liu Feiyi , Lu Qing 
Published: June 2022

AbstractThe volume detection of medical mice feed is crucial to understand the food intake requirements of mice at different growth stages and to grasp their growth, development, and health status. Aiming at the problem of volume calculation in the way of feed bulk in mice, a method for detecting the bulk volume of feed in mice based on binocular stereo vision was proposed. Firstly, the three-dimensional point coordinates of the feed's surface were calculated using the binocular stereo vision three-dimensional reconstruction technology. The coordinates of these dense points formed a point cloud, and then the projection method was used to calculate the volume of the point cloud; and finally, the volume of the mice feed was obtained. We use the stereo matching data set provided by the Middlebury evaluation platform to conduct experimental verification. The results show that our method effectively improves the matching degree of stereo matching and makes the three-dimensional point coordinates of the obtained feed's surface more accurate. The point cloud is then denoised and Delaunay triangulated, and the volume of the tetrahedron obtained after the triangulation is calculated and summed to obtain the total volume. We used different sizes of wood instead of feed for multiple volume calculations, and the average error between the calculated volume and the real volume was 7.12%. The experimental results show that the volume of the remaining feed of mice can be calculated by binocular stereo vision.