bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ergonomics 4.0: Human‐Centered Procedure for Ergonomic Design Using Virtual Reality Prototyping
Authors: Li Meng , Yao Xinhe , Aschenbrenner Doris , van Eijk Daan , Vink Peter 
Published: February 2022

AbstractWhen designing large‐scale products, like airplanes, involving the opinions from end‐users, like passengers, in conceptualization is difficult. Including user evaluation at the early stage is of foremost importance to develop products or services that reach user satisfaction. Comfort‐related assessments are particularly difficult to implement with digital models that are merely displayed on a desktop of a computer. Digital Human Modelling (DHM) benefited postural comfort analysis in the last three decades, while comfort evaluations are still largely subjective and rely on consulting with end‐users.This paper applied a human‐centered design process and used VR prototypes for comfort evaluation during concept design. This study focused on applying the Kano model with VR prototypes for concept selection and verification with potential end‐users. The results demonstrated that the first‐person immersion in VR headsets helps to identify the nuances between concepts, thus supports better decision‐making via collecting richer and more reliable user feedback to make faster and more satisfying improvements.
Toward Integrated Automation Status and Alerting Display Management Systems for Vehicles
Authors: Moertl Peter , Shi Elisabeth , Sodnik Jaka , Ebinger Nikolai , Bavendiek Jan , Mirnig Alexander , Pretto Paolo , Sarabia Joseba , Trösterer Sandra 
Published: February 2022

AbstractWith increasing levels of automation on modern vehicles, drivers need more knowledge about their vehicle than ever before. Thereby, the display of vehicle status and alerts are important means for safe and effective use. Nevertheless, there are currently no common and consistent ways of providing such status in‐formation to drivers. This is different from other domains where standardized alert management structure are common such as in modern aviation. In current vehicles, initiation, use, and termination of automated driving assistance differs considerably between vehicle models and brands and require special learning ex‐periences by the driver and alerts are not prioritized and harmonized across the various onboard systems. With higher levels of automation such complexity is expected to increase enormously. To address this problem, we propose a common taxonomy of vehicle display status and alerting terminology that is based on flight deck regulations in aviation and propose simple principles for their use in a man‐aged display status and alerting system.
Comparison of immune responses induced by two or three doses of an alum‐adjuvanted inactivated SARS‐CoV‐2 vaccine in mice
Authors: Luan Ning , Wang Yunfei , Cao Han , Lin Kangyang , Liu Cunbao 
Published: February 2022

AbstractWaning antibodies and rapidly emerging variants are challenges for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccine development. Adjusting existing immunization schedules and further boosting strategies are under consideration. Here, the immune responses induced by an alum‐adjuvanted inactivated SARS‐CoV‐2 vaccine in mice were compared among immunization schedules with two or three doses. For the two‐dose schedule, a 0–28‐day schedule induced 5‐fold stronger spike‐specific IgG responses than a 0–14‐day schedule, with only a slight elevation of spike‐specific cellular immunity 14 days after the last immunization. A third homologous boost 2 or 5 months after the second dose for the 0–28‐day schedule slightly strengthened humoral responses (1.3‐fold for the 0–1–3‐month schedule, and 1.8‐fold for the 0–1–6‐month schedule) 14 days after the last immunization. Additionally, a third homologous boost (especially with the 0–1–3‐month schedule) induced significantly stronger cell‐mediated immunity than both two‐dose immunization schedules for all indexes tested, with a response similar to that induced by a one‐dose heterologous boost with BNT162b2 in clinical trials, according to cellular immunity analysis (1.5‐fold). These T cell responses were Th2 oriented, with good CD4+ and CD8+ memory. These results may offer clues for applying a homologous boosting strategy for alum‐adjuvanted inactivated SARS‐CoV‐2 vaccines.
Determination of trans‐fatty acids in food samples based on the precolumn fluorescence derivatization by high performance liquid chromatography
Authors: Wang Fei‐Hua , Guo Xiao‐Feng , Fan Yao‐Cheng , Tang Hai‐Bin , Liang Wei , Wang Hong 
Published: February 2022

AbstractTrans‐fatty acids are unsaturated fatty acids that are considered to have health risks. 1,3,5,7‐Tetramethyl‐8‐butyrethylenediamine‐difluoroboradiaza‐s‐indacene is a highly sensitive fluorescent labeling reagent for carboxylic acids developed by our lab. In this study, using this precolumn fluorescent derivatization reagent, a rapid and accurate high‐performance liquid chromatography with fluorescence detection method was developed for the determination of two trans‐fatty acids in food samples. Under the optimized derivative conditions, two trans‐fatty acids were tagged with the fluorescent labeling reagent in the presence of 1‐ethyl‐3‐(3‐dimethyl‐aminopropyl) carbodiimide at 25°C for 30 min. Then, the baseline separation of trans‐ and cis‐fatty acids and their saturated fatty acid with similar structures was achieved with less interference using a reversed‐phased C18 column with isocratic elution in 14 min. With fluorescence detection at λex/λem = 490 /510 nm, the linear range of the TFAs was 1.0‐200 nM with low detection limits in the range of 0.1–0.2 nM (signal‐to‐noise ratio = 3). In addition, the proposed approach was successfully applied for the detection of trans‐fatty acids in food samples, and the recoveries using this method ranged from 96.02 to 109.22% with low relative standard deviations of 1.2–4.3% (n = 6).
Lake salinization drives consistent losses of zooplankton abundance and diversity across coordinated mesocosm experiments
Authors: Hébert Marie‐Pier , Symons Celia C. , Cañedo‐Argüelles Miguel , Arnott Shelley E. , Derry Alison M. , Fugère Vincent , Hintz William D. , Melles Stephanie J. , Astorg Louis , Baker Henry K. , Brentrup Jennifer A. , Downing Amy L. , Ersoy Zeynep , Espinosa Carmen , Franceschini Jaclyn M. , Giorgio Angelina T. , Göbeler Norman , Gray Derek K. , Greco Danielle , Hassal Emily , Huynh Mercedes , Hylander Samuel , Jonasen Kacie L. , Kirkwood Andrea , Langenheder Silke , Langvall Ola , Laudon Hjalmar , Lind Lovisa , Lundgren Maria , McClymont Alexandra , Proia Lorenzo , Relyea Rick A. , Rusak James A. , Schuler Matthew S. , Searle Catherine L. , Shurin Jonathan B. , Steiner Christopher F. , Striebel Maren , Thibodeau Simon , Urrutia Cordero Pablo , Vendrell‐Puigmitja Lidia , Weyhenmeyer Gesa A. , Beisner Beatrix E. 
Published: February 2022

AbstractHuman‐induced salinization increasingly threatens inland waters; yet we know little about the multifaceted response of lake communities to salt contamination. By conducting a coordinated mesocosm experiment of lake salinization across 16 sites in North America and Europe, we quantified the response of zooplankton abundance and (taxonomic and functional) community structure to a broad gradient of environmentally relevant chloride concentrations, ranging from 4 to ca. 1400 mg Cl− L−1. We found that crustaceans were distinctly more sensitive to elevated chloride than rotifers; yet, rotifers did not show compensatory abundance increases in response to crustacean declines. For crustaceans, our among‐site comparisons indicate: (1) highly consistent decreases in abundance and taxon richness with salinity; (2) widespread chloride sensitivity across major taxonomic groups (Cladocera, Cyclopoida, and Calanoida); and (3) weaker loss of functional than taxonomic diversity. Overall, our study demonstrates that aggregate properties of zooplankton communities can be adversely affected at chloride concentrations relevant to anthropogenic salinization in lakes.
Robust control for uncertain variable fractional order differential systems considering time‐varying delays and nonlinear perturbations
Authors: Wang Chunxiu , Zhou Xingde , Shi Xianzeng , Jin Yitong 
Published: February 2022

AbstractThe robust control for uncertain variable fractional order time‐varying delayed differential systems with nonlinear perturbations are concerned in this article. Firstly, by introducing a novel form of the control law which is inspired by the sliding mode design, a new state feedback controller is built. Besides, a specific and comprehensive Lyapunov–Krasovskii function is adopted to deduce the sufficient conditions for the stability and robust stabilization of the system by using some linear matrix inequalities. In addition, the controller gain matrix can also be derived from the point of stability. Finally, two comparison examples are presented to demonstrate the effectiveness of the proposed control technique. The simulation results show that this method can make the state variables converge to the steady ones more quickly and stably.
Highly clean recovery of natural antioxidants from lemon peels: Lactic acid‐based automatic solvent extraction
Authors: Toprakçı Gizem , Toprakçı İrem , Şahin Selin 
Published: February 2022

AbstractIntroductionFood industry generates large amounts of waste by‐products rich in natural antioxidants. On the other hand, application of advanced processes for the recovery of these fine chemicals is another popular topic of recent years.ObjectiveThe purpose of this study is to propose a green extraction method by application of deep eutectic solvent‐based automated solvent extraction (AMSE) from lemon peels.MethodsThe primary polyphenols (hesperidin, naringin, and p‐coumaric acid) and the total polyphenols of the lemon peel extract were quantified and used as response for the optimisation of the AMSE conditions. The Box–Behnken design type of the response surface method (RSM) was chosen for optimisation study. Scavenging activity of the lemon peel extract against 2,2‐diphenyl‐1‐picrylhydrazil (DPPH) free radical was also measured in vitro.ResultsThe optimum conditions for the highest total phenolic (7.47 mg‐gallic acid equivalent [GAE]/g‐lemon peel [LP]), naringin (5.05 mg/g‐LP), p‐coumaric acid (3.27 mg/g‐LP), and hesperidin (0.07 mg/g‐LP) yields were obtained by 1.5 h of extraction time, 46% water (v/v), and 5 g of peel. The antioxidant activity changed between 37.31% and 94.10% in the peels.ConclusionsExtraction time was the most effective process factor for the total phenolic and p‐coumaric acid yields, while water addition was statistically very important (p < 0.0001) for the naringin and hesperidin yields in the current AMSE system. The second‐order models generated for the selected systems represent the data satisfyingly based on the high coefficients of determination (> 0.99), statistically significant p‐values (<0.0001), coefficient of variation values (< 10%), and non‐significant lack‐of‐fit values (p > 0.05).
Determination of the molecular weight between cross‐links for different ambers: Viscoelastic measurements of the rubbery plateau*
Authors: Kong Dejie , Meng Yan , McKenna Gregory B. 
Published: February 2022

AbstractWhile much is known about the chemistry of amber, there are, to our knowledge, no quantitative estimates of the molecular weight between cross‐links or quantitative estimates of the amount of cross‐linking. In the present study we provide new data that advances our understanding of ancient ambers through an investigation of the network structure based on measurements of the rubbery modulus. Then, using rubber elasticity theory, we provide semiquantitative insights into the network structure. The work provides direct mechanical evidence of the chemically cross‐linked structure of a Burmese amber, a Dominican amber, a Fushun amber, and two Baltic ambers by quantifying the molecular weight between cross‐links . The values of of the studied ambers ranges from 1800 to 3000 g/mol, and the number of monomers between two cross‐link junctions is estimated to be between 6 and 10.
Enhanced chemotaxis through spatially regulated absolute concentration robustness
Authors: Biswas Debojyoti , Bhattacharya Sayak , Iglesias Pablo A. 
Published: February 2022

AbstractChemotaxis, the directional motility of cells in response to spatial gradients of chemical cues, is a fundamental process behind a wide range of biological events, including the innate immune response and cancer metastasis. Recent advances in cell biology have shown that the protrusions that enable amoeboid cells to move are driven by the stochastic threshold crossings of an underlying excitable system. As a cell encounters a chemoattractant gradient, the size of this threshold is regulated spatially so that the crossings are biased toward the front of the cell. For efficient directional migration, cells must limit undesirable lateral and rear‐directed protrusions. The inclusion of a control mechanism to suppress these unwanted firings would enhance chemotactic efficiency. It is known that absolute concentration robustness (ACR) exerts tight control over the mean and variance of species concentration. Here, we demonstrate how the coupling of the ACR mechanism to the cellular signaling machinery reduces the likelihood of threshold crossings in the excitable system. Moreover, we show that using the cell's innate gradient sensing apparatus to direct the action of ACR to the rear suppresses the lateral movement of the cells and that this results in improved chemotactic performance.
Synthesis of Stable Lead‐Free Cs3Sb2(BrxI1−x)9 (0 ≤ x ≤ 1) Perovskite Nanoplatelets and Their Application in CO2 Photocatalytic Reduction
Authors: Wu Daofu , Huo Benjun , Huang Yanyi , Zhao Xusheng , Yang Jiayu , Hu Ke , Mao Xinchun , He Peng , Huang Qiang , Tang Xiaosheng 
Published: February 2022

AbstractExploring photocatalysts to foster CO2 photoreduction into high value‐added chemicals is of great significance. Lead halide perovskites (LHPs) have recently been extensively investigated as photocatalysts, owing to their facile fabrication and prominent optoelectronic properties. However, the toxicity of lead and instability will hinder their future large‐scale applications. To address these challenges, a series of lead‐free Sb‐based all‐inorganic mixed halide perovskite Cs3Sb2(BrxI1−x)9 (0 ≤ x ≤ 1) nanoplatelets (NPLs) is synthesized. The perovskite NPLs are prepared using a ligand‐assisted re‐precipitation approach at 50 °C. The authors observe the tunability of their optical band gaps from 2.1 to 2.5 eV, and they can maintain the excellent stability over 120 h under heating at 100 °C or UV light irradiation. The resultant materials are employed as efficient photocatalysts for visible‐light driven CO2 reduction at the gas–solid interface. The Cs3Sb2(Br0.7I0.3)9 perovskite NPLs afford an impressive overall yield of 27.7 µmol g−1 for the selective photocatalytic conversion of CO2 into CO. This study represents a significant demonstration for practical artificial photosynthesis by using LHP materials as photocatalysts.
Senses of Discomfort: Negotiating Feminist Methods, Theory and Identity
Authors: van den Berg Karijn , Rezvani Leila 
Published: February 2022

AbstractOur chapter builds upon feminist understandings of the more-than-human, using our experiences of working with peasant farmers involved in seed saving (Leila) and activists’ relation to individual environmental practices (Karijn). Through a dialogue around our experiences, we reflect on feelings of discomfort, and how, rather than resolving our anxieties, discomfort has the potential to open up conventional ways of being a researcher. Focusing on relationality through embodied and processual research challenges the notion of method as a tool used by a disembodied researcher observing an inert or external world, a central concern of feminist-oriented research. We show how participating in plural and more-than-human worlds also challenges multiple binary positionings and allows for unwarranted surprises that might undo the assumptions and categories underpinning our research.
Embodying Cyberspace: Making the Personal Political in Digital Places
Authors: Harcourt Wendy , Argüello Calle Ximena 
Published: February 2022

AbstractOur chapter builds on an intergenerational transnational exchange about how feminists can create safe places of engagement via the internet as part of embodied active research processes. We tell two stories separated by over two decades that illustrate how safe feminist and queer places are co-created and embodied as vital for connections and communication in cyberspace. Inspired by feminist geographies, we employ the term “place” as a term to explain a virtual sense of belonging where people could explore possibilities of embodied politics within cyberspace. Our two stories illustrate how embodied sexuality and gender power relations are shaped in the digital world. It explores the potential for feminists in online worlds to create places where individual and collective transformative processes are possible.
Methodologies for Collaborative, Respectful and Caring Research: Conversations with Professional Indigenous Women from Mexico
Authors: Cadaval Narezo Marina 
Published: February 2022

AbstractThis chapter presents the methodological process built during my doctoral research about the expectations on graduate education and the consequent professional and community journeys of a group of indigenous women from Mexico. In this text, are explored the encounters with two women with masters degrees—a Zapotec from Oaxaca and a Maya from Yucatan—as an exercise to reflect on how to generate knowledge that considers multiple standpoints, that is collaborative, anti-oppressive, caring and follows a constant self-reflectivity. The text is also an exercise for a narrative that shows and shapes a methodological path throug time, exposing temporalities and contexts that are not fixed yet connected.
HKLL bulk reconstruction for small ∆
Authors: Aoki Sinya , Balog János 
Published: February 2022

Abstract
We discuss the extension of the HKLL (Hamilton, Kabat, Lifschytz, and Lowe) bulk reconstruction for non-interacting scalar fields corresponding to conformal weights ∆ smaller than the original condition ∆ > d − 1. We give explicit formulas for the cases d − 2 < ∆ ≤ d − 1 and ∆ = d − s with integer s. In the latter case we show that smearing CFT fields over a region of the boundary consisting of points light-like separated from the bulk point is sufficient for bulk reconstruction, whereas in general smearing over all light-like and space-like separated points is required.
Environmental influence on life-history traits in male squid Uroteuthis edulis with alternative reproductive tactics
Authors: Pang Yumeng , Chen Chih-Shin , Kawamura Tomohiko , Iwata Yoko 
Published: February 2022

AbstractSquid are characterized by flexible life-history traits (LHTs) that change in response to changing oceanic parameters. Male alternative reproductive tactics (ARTs), characterized by large-sized ‘consorts’ versus small-sized ‘sneakers’, are commonly observed in loliginid species. This study reports on LHTs flexibility in male squids displaying ARTs. LHTs of consorts and sneakers in Uroteuthis edulis, including body size, age, growth rate and gonado-somatic energy allocation, were compared among seasonal and geographical groups from Japan and Taiwan. The ratio of consorts to sneakers was highest in the group spawning in the ‘Japan-warm’ season (June–November), followed by that of the ‘Japan-cold’ season (December–May), and lowest in Taiwan (spring and autumn). LHTs were compared among cohorts separated by hatching season and catch location (Jwarm, Jcold and Taiwan cohorts). Mean body size of consorts showed no difference among cohorts, although Taiwan consorts were relatively younger than Japan consorts. Mean size and age of sneakers decreased with increased water temperature at hatching. Growth rates of consorts and sneakers were slightly different among cohorts, in accordance with differences of statolith increment widths during their early life stage (50–150 days). Growth rates of both consorts and sneakers were highest in the Taiwan cohort, followed by the Jwarm cohort, with the Jcold cohort lowest. Sneakers invested more both in mantle and gonadal weights than consorts in all cohorts. Gonado-somatic energy allocation patterns of consorts and sneakers were consistent at different temperatures. LHTs of U. edulis consorts and sneakers were strongly influenced by temperature, with higher flexibility in sneakers than consorts.
Enhanced habit formation in Tourette patients explained by shortcut modulation in a hierarchical cortico-basal ganglia model
Authors: Scholl Carolin , Baladron Javier , Vitay Julien , Hamker Fred H. 
Published: February 2022

AbstractDevaluation protocols reveal that Tourette patients show an increased propensity to habitual behaviors as they continue to respond to devalued outcomes in a cognitive stimulus-response-outcome association task. We use a neuro-computational model of hierarchically organized cortico-basal ganglia-thalamo-cortical loops to shed more light on habit formation and its alteration in Tourette patients. In our model, habitual behavior emerges from cortico-thalamic shortcut connections, where enhanced habit formation can be linked to faster plasticity in the shortcut or to a stronger feedback from the shortcut to the basal ganglia. We explore two major hypotheses of Tourette pathophysiology—local striatal disinhibition and increased dopaminergic modulation of striatal medium spiny neurons—as causes for altered shortcut activation. Both model changes altered shortcut functioning and resulted in higher rates of responses towards devalued outcomes, similar to what is observed in Tourette patients. We recommend future experimental neuroscientific studies to locate shortcuts between cortico-basal ganglia-thalamo-cortical loops in the human brain and study their potential role in health and disease.
Digital shinrin-yoku: do nature experiences in virtual reality reduce stress and increase well-being as strongly as similar experiences in a physical forest?
Authors: Reese Gerhard , Stahlberg Jasmin , Menzel Claudia 
Published: February 2022

AbstractShinrin-yoku or forest bathing refers to a therapeutic, immersive nature experience that aids to improve well-being. The goal of the current research was to compare the effects of a physical urban nature versus virtual nature experience on stress, affect, vitality, and restoration. Previous research suggested that an immersive nature experience—such as shinrin-yoku—can be beneficial for health, but direct comparisons between physical and virtual reality (VR) experiences are scarce. In the current study, fifty participants navigated self-paced through a forest scene that was either an urban physical forest or an immersive VR forest with similar characteristics as the physical one. Before and after the intervention, we measured positive and negative affect, subjective vitality, and perceived daily stress. After the intervention, we measured perceived restorative outcomes. Results revealed that both VR and physical nature experience resulted in expected effects on well-being indicators: Affect was more positive and less negative, subjective vitality increased slightly, and stress decreased slightly after both interventions. There were no significant differences between the two settings on any of the variables, but slightly stronger effect sizes over time within the physical condition. Overall, these findings suggest that immersive VR nature experiences can have restoration effects similar to physical nature experiences, suggesting intervention strategies when physical nature options are scarce.