bluuebunny/crossref_metadata_2025_split huggingface dataset:
FunAndes – A functional trait database of Andean plants
Authors: Báez Selene , Cayuela Luis , Macía Manuel J. , Álvarez-Dávila Esteban , Apaza-Quevedo Amira , Arnelas Itziar , Baca-Cortes Natalia , Bañares de Dios Guillermo , Bauters Marijn , Ben Saadi Celina , Blundo Cecilia , Cabrera Marian , Castaño Felipe , Cayola Leslie , de Aledo Julia G. , Espinosa Carlos Iván , Fadrique Belén , Farfán-Rios William , Fuentes Alfredo , Garnica-Díaz Claudia , González Mailyn , González Diego , Hensen Isabell , Hurtado Ana Belén , Jadán Oswaldo , Lippok Denis , Loza M. Isabel , Maldonado Carla , Malizia Lucio , Matas-Granados Laura , Myers Jonathan A. , Norden Natalia , Oliveras Menor Imma , Pierick Kerstin , Ramírez-Angulo Hirma , Salgado-Negret Beatriz , Schleuning Matthias , Silman Miles , Solarte-Cruz María Elena , Tello J. Sebastián , Verbeeck Hans , Vilanova Emilio , Weithmann Greta , Homeier Jürgen 
Published: August 2022

AbstractWe introduce the FunAndes database, a compilation of functional trait data for the Andean flora spanning six countries. FunAndes contains data on 24 traits across 2,694 taxa, for a total of 105,466 entries. The database features plant-morphological attributes including growth form, and leaf, stem, and wood traits measured at the species or individual level, together with geographic metadata (i.e., coordinates and elevation). FunAndes follows the field names, trait descriptions and units of measurement of the TRY database. It is currently available in open access in the FIGSHARE data repository, and will be part of TRY’s next release. Open access trait data from Andean plants will contribute to ecological research in the region, the most species rich terrestrial biodiversity hotspot.
Strong ground motion data of the 2015 Gorkha Nepal earthquake sequence in the Kathmandu Valley
Authors: Shigefuji Michiko , Takai Nobuo , Bijukchhen Subeg , Ichiyanagi Masayoshi , Rajaure Sudhir , Dhital Megh Raj , Paudel Lalu Prasad , Sasatani Tsutomu 
Published: August 2022

AbstractStrong-motion records of earthquakes are used not only to evaluate the source rupture process, seismic wave propagation and strong ground motion characteristics, but also to provide valuable data for earthquake disaster mitigation. The Kathmandu Valley, Nepal, which is characterised by having soft sediments that have been deposited in an earthquake-prone zone, has experienced numerous earthquakes. We have operated four strong-motion stations in the Kathmandu Valley since 2011. These stations recorded the 2015 magnitude 7.8 Gorkha Nepal earthquake that occurred in the Himalayan continental collision zone. For several months after the mainshock, we deployed four additional temporary stations. Here, we describe the seismic data for 18 earthquakes over magnitude 5.0 collected by this array, including the 2015 magnitude 7.3 Dolakha earthquake of maximum aftershock and three large aftershocks of magnitude 6-class. These data are essential for validating the sedimentary structure of the basin and for evaluating the hazard and risk of future earthquakes in the Kathmandu Valley.
Development of a scoring system with multidimensional markers for fibrosing interstitial lung disease
Authors: Shi Shenyun , Chen Lulu , Liu Xiaoqin , Yu Min , Wu Chao , Xiao Yonglong 
Published: August 2022

AbstractFibrosing interstitial lung disease (ILD) can cause high mortality and sensitive evaluation of fibrosing ILD could be critical. The aim of this study is to develop a scoring system to predict prognosis of fibrosing ILD. 339 patients with fibrosing ILD were enrolled as a derivation cohort. Cox multiple regression analysis indicated that smoking history (HR  =  3.826, p  =  0.001), age(HR  =  1.043, p  =  0.015), CEA(HR  =  1.059, p  =  0.049),CYFRA21-1(HR  =  1.177, p  =  0.004) and DLCO% predicted (HR  =  0.979, p  =  0.032) were independent prognostic factors for fibrosing ILD. The clinical scoring system for fibrosing ILD was established based on the clinical variables (age [A], CEA and CYFRA21-1 [C], DLCO% predicted [D], and smoking history [S]; ACDS). The area under the receiver operating characteristic curve (AUROC) of the scoring system for predicting prognosis of fibrosing ILD was 0.90 (95%CI: 0.87–0.94, p < 0.001). The cutoff value was 2.5 with their corresponding specificity (90.7%) and sensitivity (78.8%). To validate the value of ACDS score levels to predict the survival of patients with fibrosing ILD, 98 additional fibrosing ILD patients were included as a validation cohort. The log-rank test showed a significant difference in survival between the two groups(ACDS score < 2.5 and ACDS score ≥ 2.5) in validation cohort. The independent risk factors for mortality in patients with fibrosing ILD are higher CEA, higher CYFRA21-1, smoking history, lower DLCO%predicted at baseline and older age. ACDS is a simple and feasible clinical model for predicting survival of fibrosing ILD.
A secondary EWMA-based dictionary learning algorithm for polynomial phase signal denoising
Authors: Ou Guojian , Zou Sai , Liu Song , Tang Jianguo 
Published: August 2022

AbstractUnder the influence of additive white Gaussian noise, sparse representation cannot effectively remove noise associated with the polynomial phase signal (PPS) via most dictionary learning algorithms whose training data come from the noisy signal, such as K-SVD and RLS-DLA. In this paper, we present a novel dictionary learning algorithm based on secondary exponentially weighted moving average (SEWMA) to denoise PPS. In the proposed algorithm, we first estimate the signal-to-noise (SNR) of the PPS to set the optimal rate of a weighted decline using covariance matrix model. Second we use RLS-DLA to train the dictionary. Thirdly, SEWMA is used to refine atoms in the learned dictionary. In this way, the SNR of the reconstructed signal obtained using the proposed algorithm is clearly higher than that of other algorithms, whereas the mean squared error is lower than that of other algorithms. To obtain the optimal denoising performance, the optimal rate of a weighted decline is set based on the estimated SNR. Simulation results show that the proposed method outperforms the K-SVD, RLS-DLA in mean square error and the SNR.
Neuronal effects of glabellar botulinum toxin injections using a valenced inhibition task in borderline personality disorder
Authors: Kruger Tillmann H. C. , Schulze Jara , Bechinie Agnès , Neumann Insa , Jung Stefanie , Sperling Christian , Engel Jannis , Müller Antje , Kneer Jonas , Kahl Kai G. , Karst Matthias , Herrmann Julian , Fournier-Kaiser Larissa , Peters Liza , Jürgensen Frank , Nagel Matthias , Prager Welf , Dulz Birger , Wohlmuth Peter , Heßelmann Volker , Sinke Christopher , Wollmer M. Axel 
Published: August 2022

AbstractPrevious studies have indicated that glabellar botulinum toxin (BTX) injections may lead to a sustained alleviation of depression. This may be accomplished by the disruption of a facial feedback loop, which potentially mitigates the experience of negative emotions. Accordingly, glabellar BTX injection can attenuate amygdala activity in response to emotional stimuli. A prototypic condition with an excess of negative emotionality and impulsivity accompanied by elevated amygdala reactivity to emotional stimuli is borderline personality disorder (BPD). In order to improve the understanding of how glabellar BTX may affect the processing of emotional stimuli and impulsivity, we conducted a functional magnetic resonance imaging (fMRI) study. Our hypotheses were (1) glabellar BTX leads to increased activation in prefrontal areas during inhibition performance and (2) BTX decreases amygdala activity during the processing of emotional stimuli in general. Using an emotional go-/no-go paradigm during fMRI, the interference of emotion processing and impulsivity in a sample of n = 45 women with BPD was assessed. Subjects were randomly assigned to BTX treatment or serial acupuncture (ACU) of the head. After 4 weeks, both treatments led to a reduction in the symptoms of BPD. However, BTX treatment was specifically associated with improved inhibition performance and increased activity in the motor cortex. In addition, the processing of negative emotional faces was accompanied by a reduction in right amygdala activity. This study provides the first evidence that glabellar BTX injections may modify central neurobiological and behavioural aspects of BPD. Since the control treatment produced similar clinical effects, these neurobiological findings may be specific to BTX and not a general correlate of symptomatic improvement.
Evaluation of a hybrid pipeline for automated segmentation of solid lesions based on mathematical algorithms and deep learning
Authors: Burrows Liam , Chen Ke , Guo Weihong , Hossack Martin , McWilliams Richard G. , Torella Francesco 
Published: August 2022

AbstractWe evaluate the accuracy of an original hybrid segmentation pipeline, combining variational and deep learning methods, in the segmentation of CT scans of stented aortic aneurysms, abdominal organs and brain lesions. The hybrid pipeline is trained on 50 aortic CT scans and tested on 10. Additionally, we trained and tested the hybrid pipeline on publicly available datasets of CT scans of abdominal organs and MR scans of brain tumours. We tested the accuracy of the hybrid pipeline against a gold standard (manual segmentation) and compared its performance to that of a standard automated segmentation method with commonly used metrics, including the DICE and JACCARD and volumetric similarity (VS) coefficients, and the Hausdorff Distance (HD). Results. The hybrid pipeline produced very accurate segmentations of the aorta, with mean DICE, JACCARD and VS coefficients of: 0.909, 0.837 and 0.972 in thrombus segmentation and 0.937, 0.884 and 0.970 for stent and lumen segmentation. It consistently outperformed the standard automated method. Similar results were observed when the hybrid pipeline was trained and tested on publicly available datasets, with mean DICE scores of: 0.832 on brain tumour segmentation, and 0.894/0.841/0.853/0.847/0.941 on left kidney/right kidney/spleen/aorta/liver organ segmentation.
Molecular neurobiological markers in the onset of sodium appetite
Authors: Porcari Cintia Y. , Cambiasso María J. , Mecawi André S. , Caeiro Ximena E. , Antunes-Rodrigues José , Vivas Laura M. , Godino Andrea 
Published: August 2022

AbstractSodium appetite is a motivational state involving homeostatic behavior, seeking the ingest of salty substances after sodium loss. There is a temporal dissociation between sodium depletion (SD) and the appearance of sodium appetite. However, the responsible mechanisms for this delay remain poorly elucidated. In the present study, we measured the temporal changes at two and 24 h after SD in the gene expression of key elements within excitatory, inhibitory, and sensory areas implicated in the signaling pathways involved in the onset of sodium appetite. In SD rats, we observed that the expression of critical components within the brain control circuit of sodium appetite, including Angiotensin-type-1 receptor (Agtr1a), Oxytocin-(OXT-NP)-neurophysin-I, and serotonergic-(5HT)-type-2c receptor (Htr2c) were modulated by SD, regardless of time. However, we observed reduced phosphorylation of mitogen-activated protein kinases (MAPK) at the paraventricular nucleus (PVN) and increased oxytocin receptor (Oxtr) mRNA expression at the anteroventral of the third ventricle area (AV3V), at two hours after SD, when sodium appetite is inapparent. At twenty-four hours after SD, when sodium appetite is released, we observed a reduction in the mRNA expression of the transient receptor potential channel 1gene (Trpv1) and Oxtr in the AV3V and the dorsal raphe nucleus, respectively. The results indicate that SD exerts a coordinated timing effect, promoting the appearance of sodium appetite through changes in MAPK activity and lower Trpv1 channel and Oxtr expression that trigger sodium consumption to reestablish the hydroelectrolytic homeostasis.
Analysis and design of ultra-wideband PRGW hybrid coupler using PEC/PMC waveguide model
Authors: Mousavirazi Zahra , Ali Mohamed Mamdouh M. , Gheisanab Hassan Naseri , Denidni Tayeb A. 
Published: August 2022

AbstractIn this paper, a new method to facilitate the design of Printed Ridge Gap Waveguide (PRGW) structures is introduced. One of the main difficulties in designing such structures is related to their simulation process which is really time and energy-consuming. Therefore, a suitable boundary condition is considered to bring about the primary structure without involving the bed of nails or mushroom unit cells. Using this technique, a wideband PRGW 3 dB hybrid double-box coupler is designed to serve in mm-wave frequencies at a center frequency of 30 GHz, which can be deployed for the next generation of mobile communication. The designed coupler provides a wide matching and isolation bandwidth with low output amplitude imbalance, which is unique in comparison with current couplers. The prototype of the proposed coupler is fabricated and measured where the simulation and measurement results show a good agreement indicating the strength of the proposed method in PRGW structure design as well. The measured results show the couplers achieve better than 10-dB return loss and isolation over the frequency range from 25 to 40 GHz (46% BW) with the power-split unbalance and phase error within ± 1 dB and ± 5°, respectively. In addition, square mushrooms are chosen here to satisfy the high impedance surface. Not only do they bring about larger stop bandwidth, but also their configuration facilitates the arrangement of them around the coupler. The proposed design has superb characteristics such as low profile, low loss, and easy integration with microwave circuits and systems that can be suitable for designing mm-wave beamforming networks.
Impact of mirabegron versus solifenacin on autonomic function and arterial stiffness in female overactive bladder syndrome: a randomized controlled trial
Authors: Hsiao Sheng-Mou , Tu Fung-Chao , Su Ta-Chen , Wu Pei-Chi , Lin Ho-Hsiung 
Published: August 2022

AbstractThe study aims to elucidate the impact of mirabegron versus solifenacin on autonomic function and peripheral arterial conditions in women with overactive bladder syndrome (OAB). All consecutive women with OAB were randomized to receive 12 weeks of mirabegron 25 mg or solifenacin 5 mg once per day. Heart rate variability, cardio-ankle vascular index, ankle-brachial pressure index, blood pressure, and heart rate were compared between the two groups. There were 87 women (mirabegron, n = 43; and solifenacin, n = 44) who completed 12-week treatment and underwent heart rate variability examination. Systolic blood pressure (median: − 4.5 to − 5.5 mmHg) and diastolic blood pressure (median: − 0.5 to − 3.5 mmHg) decreased after solifenacin treatment, and heart rate (median: + 2 bpm) increased after mirabegron treatment, despite of no between-group difference. In addition, posttreatment heart rate variability, cardio-ankle vascular index, and ankle-brachial pressure index did not differ compared with baseline; and there were no between-group differences. In conclusion, solifenacin might decrease blood pressure, and mirabegron might increase heart rate. Nonetheless, there were no significant impacts of 12-week mirabegron versus solifenacin treatment on autonomic function and arterial stiffness.
Reconfigurable electro-optical logic gates using a 2-layer multilayer perceptron
Authors: Lin Chu-En , Lu Yueh-Heng , Zhou Meng-Ting , Chen Chii-Chang 
Published: August 2022

AbstractIn this work, we aim to use the optical amplifiers, directional couplers and phase modulators to build the electro-optical gates. Thanks to the 2-layer-multilayer-perceptron structure, the inversion of matrix is performed to obtain the coupling ratio of the directional couplers and the phase delay of the phase modulators. The electro-optical OR, AND, XOR, NAND, NOR and XNOR gates are demonstrated. Moreover, we not only study the results under the ideal condition of device, but also discuss the imperfect situation with 1% error of fabrication or operation to study the tolerance of this system. Through our simulation results, the visibility of the gate output can be higher than 0.83. The gates can be fabricated in a silicon-based chip to develop the integrated optics computing system.
Effects of extracellular vesicles derived from oral bacteria on osteoclast differentiation and activation
Authors: Kim Hyun Young , Song Min-Kyoung , Lim Younggap , Jang Ji Sun , An Sun-Jin , Kim Hong-Hee , Choi Bong-Kyu 
Published: August 2022

AbstractDysbiosis of the oral microbiota plays an important role in the progression of periodontitis, which is characterized by chronic inflammation and alveolar bone loss, and associated with systemic diseases. Bacterial extracellular vesicles (EVs) contain various bioactive molecules and show diverse effects on host environments depending on the bacterial species. Recently, we reported that EVs derived from Filifactor alocis, a Gram-positive periodontal pathogen, had osteoclastogenic activity. In the present study, we analysed the osteoclastogenic potency and immunostimulatory activity of EVs derived from the Gram-negative periodontal pathogens Porphyromonas gingivalis and Tannerella forsythia, the oral commensal bacterium Streptococcus oralis, and the gut probiotic strain Lactobacillus reuteri. Bacterial EVs were purified by density gradient ultracentrifugation using OptiPrep (iodixanol) reagent. EVs from P. gingivalis, T. forsythia, and S. oralis increased osteoclast differentiation and osteoclstogenic cytokine expression in osteoclast precursors, whereas EVs from L. reuteri did not. EVs from P. gingivalis, T. forsythia, and S. oralis preferentially activated Toll-like receptor 2 (TLR2) rather than TLR4 or TLR9, and induced osteoclastogenesis mainly through TLR2. The osteoclastogenic effects of EVs from P. gingivalis and T. forsythia were reduced by both lipoprotein lipase and polymyxin B, an inhibitor of lipopolysaccharide (LPS), while the osteoclastogenic effects of EVs from S. oralis were reduced by lipoprotein lipase alone. These results demonstrate that EVs from periodontal pathogens and oral commensal have osteoclastogenic activity through TLR2 activation by lipoproteins and/or LPS.
Moral parochialism and causal appraisal of transgressive harm in Seoul and Los Angeles
Authors: Holbrook Colin , Yoon Leehyun , Fessler Daniel M. T. , Moser Cody , Delgado Shairy Jimenez , Kim Hackjin 
Published: August 2022

AbstractThe evolutionary fitness payoffs of moral condemnation are greatest within an individual’s immediate social milieu. Accordingly, insofar as human moral intuitions have been shaped by adaptive design, we can expect transgressive harms to be perceived as more wrong when transpiring in the here and now than when occurring at a distance, or with the approval of local authority figures. Thismoral parochialismhypothesis has been supported by research conducted in diverse societies, but has yet to be tested in an East Asian society, despite prior research indicating that East Asians appraise transgressive acts as being caused by situational and contextual factors to a greater extent than do Westerners, who tend to emphasize dispositional factors (i.e., the transgressor’s personal nature). Here, in a quasi-experiment using field samples recruited in Seoul and Los Angeles, we tested (i) the moral parochialism hypothesis regarding the perceived wrongness of transgressions, as well as (ii) the extent to which these wrongness judgments might be influenced by cross-cultural differences in causal appraisals. Despite notably large differences across the two societies in situational versus dispositional appraisals of the causes of the transgressions, replicating previous findings elsewhere, in both societies we found that transgressions were deemed less wrong when occurring at spatial or temporal remove or with the consent of authorities. These findings add to the understanding of morality as universally focused on local affairs, notwithstanding cultural variation in perceptions of the situational versus dispositional causes of (im)moral acts.
Pre-diagnostic DNA methylation in blood leucocytes in cutaneous melanoma; a nested case–control study within the Norwegian Women and Cancer cohort
Authors: Page Christian M. , Nøst Therese H. , Djordjilović Vera , Thoresen Magne , Frigessi Arnoldo , Sandanger Torkjel M. , Veierød Marit B. 
Published: August 2022

AbstractThe prognosis of cutaneous melanoma depends on early detection, and good biomarkers for melanoma risk may provide a valuable tool to detect melanoma development at a pre-clinical stage. By studying the epigenetic profile in pre-diagnostic blood samples of melanoma cases and cancer free controls, we aimed to identify DNA methylation sites conferring melanoma risk. DNA methylation was measured at 775,528 CpG sites using the Illumina EPIC array in whole blood in incident melanoma cases (n = 183) and matched cancer-free controls (n = 183) in the Norwegian Women and Cancer cohort. Phenotypic information and ultraviolet radiation exposure were obtained from questionnaires. Epigenome wide association (EWAS) was analyzed in future melanoma cases and controls with conditional logistic regression, with correction for multiple testing using the false discovery rate (FDR). We extended the analysis by including a public data set on melanoma (GSE120878), and combining these different data sets using a version of covariate modulated FDR (AdaPT). The analysis on future melanoma cases and controls did not identify any genome wide significant CpG sites (0.85 ≤ padj ≤ 0.99). In the restricted AdaPT analysis, 7 CpG sites were suggestive at the FDR level of 0.15. These CpG sites may potentially be used as pre-diagnostic biomarkers of melanoma risk.
Hexavalent chromium elimination from wastewater by integrated micro-electrolysis composites synthesized from red mud and rice straw via a facile one-pot method
Authors: Wang Huabin , Cui Ting , Chen Dingxiang , Luo Qiong , Xu Jiwei , Sun Rong , Zi Wenhua , Xu Rui , Liu Ying , Zhang Yong 
Published: August 2022

AbstractThe widely spread chromium (Cr) contamination is rising environmental concerns, while the reutilization of agro-industrial by-products are also urgently demanded due to their potential risks. In this study, we prepared the integrated micro-electrolysis composites (IMC) through a facile one-pot method with red mud and rice straw. The effects of components relatively mass ratios as well as pyrolysis temperature were analyzed. The XRD, XPS, SEM, FTIR, and various techniques proved the IMC was successfully synthesized, which was also used to analyze the reaction mechanisms. In this study, the dosage of IMC, pH, adsorption time, and temperature of adsorption processes were explored, in the adsorption experiment of Cr(VI), dosage of IMC was 2 g/L (pH 6, 25 °C, and 200 rpm) for isothermal, while the concentration and contact time were also varied. According to the batch experiments, IMC exhibited acceptable removal capacity (190.6 mg/g) on Cr(VI) and the efficiency reached 97.74%. The removal mechanisms of adsorbed Cr(VI) were mainly elaborated as chemical reduction, complexation, co-precipitation, and physical adherence. All these results shed light on the facile preparation and agro-industrial by-products recycled as engineering materials for the heavy metals decontamination in wastewater.