bluuebunny/crossref_metadata_2025_split huggingface dataset:
The best-fitting model(s) of equal risk contribution: evidence from environmental-friendly portfolio
Authors: Nugroho Bayu Adi 
Published: June 2022

PurposeThis research aims to select the best-fitting model(s) of equal risk contribution portfolios (ERC). ERC is a robust estimation in the absence of reasonable expectations about future returns.Design/methodology/approachThe portfolio consists of five environmental-friendly exchange-traded funds (ETFs). It applies equal risk optimization, beneficial when the assets are firmly linked, such as the ETFs. This paper operationalizes 20 covariance models in portfolio construction, and a portfolio with classic covariance is the benchmark to beat. To select the best-fitting model(s), the paper applies statistical inferences of the model confidence set. This research also constructs the newly-developed minimum connectedness optimization method and utilizes maximum drawdown as the primary evaluation tool.FindingsThe outbreak of COVID-19 hugely impacts the portfolio drawdown. The results also show that the classic covariance is hard to beat, partly explained by estimation error and model misspecification. This paper suggests that equal risk contribution can benefit from copula-based covariance. It consistently and significantly outperforms the other models in various robustness tests.Practical implicationsIn the absence of substantial predictions about future returns and the existence of strongly linked assets, selecting appropriate portfolio components by risk contribution is a sound choice.Originality/valueThis is the first paper to select the best-fitting model(s) of ERC portfolio during the COVID-19.
How the COVID-19 pandemic may accelerate millennials’ adoption of augmented reality
Authors: Caboni Federica , Pizzichini Lucia 
Published: June 2022

PurposeAugmented reality (AR) technology currently plays a central role in the retail sector, rapidly changing consumers’ behaviours and retailers’ strategies. The purpose of this paper is to identify the behavioural changes that have occurred due to the coronavirus disease 2019 (COVID-19) pandemic in the retail sector, and how AR technology can be used as a valid and useful response to these new consumer habits.Design/methodology/approachExploratory research was conducted to determine how AR has helped people shop differently than they did before the coronavirus disease 2019 (COVID-19) pandemic by evaluating two retail-sector AR applications (apps). In-depth interviews were conducted and assessed using thematic analysis.FindingsThis paper identifies a new paradigm involving COVID-19 and AR by identifying several factors that are related to the rapid spread of COVID-19 and have modified consumers’ shopping habits. Additionally, it shows how interactive technologies, such as AR, are useful tools that can be employed to overcome retailing crises driven by external environmental factors, such as COVID-19, and enhance shopping experiences.Originality/valueThis research reveals the role of AR technologies in transformed economic and social contexts. By investigating the COVID-19 pandemic and its associated consequences, i.e. isolation, quarantines and lockdowns; the fear of contracting the virus and the new needs of people to shop while social distancing, this study enriches AR research with a fourth characteristic, augmented social distance.
The De Winter‐like electrocardiogram pattern associated with multi‐vessel disease
Authors: Wang Chunfang , Yan Hongli , Wang Jian 
Published: June 2022

AbstractBackgroundThe de Winter ECG pattern was described by upsloping ST‐segment depression in leads V1‐V6, tall and symmetrical T waves in precordial leads. The ECG pattern is regarded to be associated with occlusion of the left anterior descending (LAD) artery.MethodsOne patient with de Winter ECG pattern was included. The 12‐lead ECG of patients with chest pain showed upsloping ST‐segment depression up to 3 mm at the J point in leads V2‐V6; tall symmetrical T waves in leads V2‐V4; 1mm J point elevation in lead aVR; ST‐segment depression 1mm in I, aVL leads and inverted T waves in the inferior leads. The ECG was showed the de Winter pattern.ResultsThe ECG was showed the de Winter pattern. CAG was performed, which showed the normal left main; 60%‐80% LAD stenosis; 50%‐60% ostial right coronary artery(RCA) stenosis; and 90% stenosis of the vessel at middle segment. Both proximal and middle RCA vascular lesions were dilated and successfully inserted with drug‐eluting stents, respectively.ConclusionOur case the ECG was showed horizontal ST depression with tall T waves in leads V2‐V4 (maximal ST depression in lead V4) while only ST depression in leads V5‐V6, which may result from multivessel disease.
Beta‐thalassaemia major: Prevalence, risk factors and clinical consequences of hypercalciuria
Authors: Aliberti Ludovica , Gagliardi Irene , Gamberini Maria Rita , Ziggiotto Andrea , Verrienti Martina , Carnevale Aldo , Bondanelli Marta , Zatelli Maria Chiara , Ambrosio Maria Rosaria 
Published: June 2022

SummaryRegular transfusion and chelation therapy produces increased life expectancy in thalassaemic patients who may develop new complications. Since few data are available regarding hypercalciuria in β‐thalassaemia major (TM), the aim of our study was to evaluate its prevalence, risk factors and clinical consequences. We enrolled 176 adult TM patients followed at the Center of Thalassemia of Ferrara. Hypercalciuria was defined by a calciuria of 4 mg/kg/day or more in a 24‐h urine sample. Anamnestic, biochemical and radiological data were collected. Hypercalciuria prevalence was reported in 69.3% of patients (females 52.5%). Hypercalciuric (HC) patients used deferasirox (DFX) more often than normocalciuric (NC) patients (47.5% vs 29.6%; p < 0.05). In HC subjects plasma parathyroid hormone (PTH) (24.1 ± 10.4 vs 30.1 ± 13.2 pg/ml) and phosphate levels (3.6 ± 0.5 vs 3.8 ± 0.7 mg/dl) were lower, whereas serum calcium (9.6 ± 0.4 vs 9.4 ± 0.4 mg/dl) and urinary 24‐h phosphaturia (0.9 ± 0.4 vs 0.6 ± 0.3 g/day) were higher as compared to NC patients (p < 0.05 for all comparisons). Supplementation with oral calcium and cholecalciferol was similar between the groups. A higher rate of kidney stones was present in HC (14.8%) versus NC patients (3.7%) (p < 0.05). Hypercalciuria is a frequent complication in adequately treated adult TM patients. Hypercalciuria prevalence is increased in DFX users whereas haemoglobin level or calcium supplements play no role. A significant proportion of HC patients developed kidney stones.
Peripubertal requirement of Tsg101 in maintaining the integrity of membranous structures in mouse oocytes
Authors: Shin Hyejin , Park Dayoung , Kim Jiyeon , Nam Min‐Yeong , Kwon Sojung , Um Da‐Eun , Oh Ji‐Eun , Youn Esther , Shim Yhong‐Hee , Wagner Kay‐Uwe , Jun Jin Hyun , Kim Hye‐Ryun , Song Haengseok , Lim Hyunjung Jade 
Published: June 2022

AbstractObjectiveAs a component of Endosomal Sorting Complex Required for Transport (ESCRT) complex I, the tumor susceptibility gene 101 (Tsg101) carries out multiple functions. In this work, we report that oocyte‐specific deletion of tumor susceptibility gene 101 (Tsg101) leads to age‐dependent oocyte demise in mice.Materials and MethodTsg101 floxed mice (Tsg101f/f) were bred with Zp3cre transgenic mice to examine oocyte‐specific roles of Tsg101. Multiple cellular and molecular biological approaches were taken to examine what leads to oocyte demise in the absence of Tsg101.ResultsThe death of oocytes from Zp3cre/Tsg101f/f (Tsg101d/d thereafter) mice showed a strong correlation with sexual maturation, as gonadotropin‐releasing hormone antagonist injections improved the survival rate of oocytes from 5‐week‐old Tsg101d/d mice. Maturation of oocytes from prepubertal Tsg101d/d mice proceeded normally, but was largely abnormal in oocytes from peripubertal Tsg101d/d mice, showing shrinkage or rupture. Endolysosomal structures in oocytes from peripubertal Tsg101d/d mice showed abnormalities, with aberrant patterns of early and late endosomal markers and a high accumulation of lysosomes. Dying oocytes showed plasma membrane blebs and leakage. Blockage of endocytosis in oocytes at 4°C prevented cytoplasmic shrinkage of oocytes from Tsg101d/d mice until 9 h. The depletion of tsg‐101 in Caenorhabditis elegans increased the permeability of oocytes and embryos, suggesting a conserved role of Tsg101 in maintaining membrane integrity.ConclusionsCollectively, Tsg101 plays a dual role in maintaining the integrity of membranous structures, which is influenced by age in mouse oocytes.
Incidentally identified left ventricular apical aneurysm in a patient with Fabry disease
Authors: Yim Jeffrey , Gin Kenneth , Tsang Teresa S. M. , Luong Christina , Lehman Anna , Ong Kevin , Tsang Michael Y. C. , Jue John , Nair Parvathy , Nasmith Trudy , Yeung Darwin F. 
Published: June 2022

AbstractFabry disease is a rare X‐linked lysosomal storage disorder caused by a deficiency in the lysosomal enzyme, galactosidase A, that can result in a progressive increase in the left ventricle (LV) wall thickness from glycosphingolipid deposition leading to myocardial fibrosis, conduction abnormalities, arrhythmias, and heart failure. We present a case of a patient with advanced Fabry cardiomyopathy, in whom a small LV apical aneurysm was incidentally discovered on abdominal imaging, which could have easily evaded detection on standard transthoracic echocardiography. The LV apex should be thoroughly interrogated in patients with Fabry cardiomyopathy, as the finding of LV aneurysm could have important management implications with respect to the prevention of stroke and sudden cardiac death.
Insights on selection of undergraduate dental students
Authors: Cunningham Claudia , Kiezebrink Kirsty 
Published: June 2022

AbstractIntroductionThe goal of selection to dental education was to find those with the greatest aptitude for dentistry. Recently, schools have introduced a variety of tools; however, these have often been adopted without appropriate evaluation regarding existing evidence for fairness, reliability or validity.We explore dental admissions staff beliefs about the quality of different selection tools, with the objective of exploring their decision‐making in implementing selection practices.MethodsThis qualitative study is underpinned by a social constructionist epistemology, in which our principal concern is “explicating the processes by which people come to describe, explain or otherwise account for the world (including themselves) in which they live.” We conducted individual interviews with 15 of the 16 UK dental admission leads to elicit their views around admissions processes and aims. Data coding and analysis were initially inductive, using thematic analysis. After the themes emerged, we applied a deductive framework of affordances to group themes and then examined these for heuristics.Results and DiscussionWe identified three main themes; “Selection Tool Use,” “Widening Participation Practices,” and “Professionalising the Admission Lead Role.” Admission leads spoke favourably of tools that allowed a “holistic” view of the applicants “potential”. Selection tools were favoured if they enabled “Gut feeling”. Leads spoke of evaluating candidates, making sure they were “rounded”, and “know what dentistry is all about.” In justifying the use of elements of their procedure, the use of heuristics was prominent.ConclusionIn order to minimise the potential consequences of poor selection decisions, it is important to acknowledge that dental admission leads are at risk of depending on sub‐optimal heuristics to make judgements about effective selection (shaped by previous practices) rather than using more rational decision‐making processes based on the extant evidence (regarding the quality of different selection tools). Future research may be usefully informed by the knowledge translation literature to offer solutions for improving selection practices in dental education.
Dreams as Deep Play: Toward a Cultural Understanding of Dreaming
Authors: Mageo Jeannette 
Published: June 2022

AbstractThis article develops a cultural theory of those dreams with rich imagery and developed plots that are likely to be dreamt in rapid‐eye‐movement sleep. Such dreams, it argues, are an instance of what the anthropologist Clifford Geertz calls “deep play.” For Geertz, deep play is play with “an image … a model, a metaphor” that makes visible fundamental cultural structures. Image metaphors for cultural models often appear in dreams. Deep play in dreams, I argue, subjects cultural models to destabilizing play in order to adapt them to the dreamer's experience and to confront threats to the dreamer's identity that models for being a person can pose. Dreamers destabilize models by ambiguating images that represent them in seven ways outlined in the article. Ambiguity stops the mind from settling on a single meaning. This inability triggers hyper‐associations that challenge and subvert a model's given meanings. Two dreams from an undergraduate who participated in a study of dreaming at a major Northwestern university illustrate these ideas.
Consumers' emotional responses evoked by fermented rice noodles containing crickets and/or mango peel: impact of product information and prior insect consumption
Authors: Maw Win Win , Sae‐Eaw Amporn , Wongthahan Peerapong , Prinyawiwatkul Witoon 
Published: June 2022

SummaryExpected sensory liking and emotional profiles of three fermented rice noodles containing cricket (P‐cp), mango peel (P‐mp) and a combination of cricket and mango peel (P‐cp*mp) were virtually evaluated using an online survey (n = 727 consumers). Data were grouped by consumers as follows: consumers, who had consumed cricket, participating in the online survey before (C‐eb) or after (C‐ea) receiving product information; and consumers, who had never consumed cricket, participating in the online survey before (C‐nb) or after (C‐na) receiving product information. Expected overall sensory liking and emotional profiles were analysed using ANOVA and Correspondence Analysis, respectively. C‐ea rated all products with the highest expected sensory liking scores. P‐cp and P‐cp*mp evoked more negative emotions than did P‐mp. Consumers who did not receive information and/or those who never consumed crickets mainly expressed negative emotions. More specifically, C‐ea mostly exhibited positive emotions, whereas C‐na elicited more negative emotions for all products. This study concluded that consumers' expected sensory liking and emotional profiles of fermented rice noodles containing cricket (P‐cp) were influenced by additional product information and prior cricket consumption experience. This finding would be useful for introduction of products containing cricket.
Management of hydronephrosis after radical cystectomy and urinary diversion for bladder cancer: A single tertiary center experience
Authors: Tanaka Toshiaki , Shindo Tetsuya , Hashimoto Kohei , Kobayashi Ko , Masumori Naoya 
Published: June 2022

ObjectivesTo clarify the incidence of postoperative hydronephrosis and verify the validity of diagnostic and therapeutic approaches for hydronephrosis after cystectomy and urinary diversion for bladder cancer.MethodsTotally, 290 patients receiving urinary diversion from 2005 through 2017 with complete data were enrolled, including 258 (89.0%) with an ileal conduit and 32 (11.0%) with an ileal neobladder. Postoperative radiographic images were reviewed. In patients with postoperative hydronephrosis, antegrade pyelography and ureteroscopy were performed to exclude malignant etiology. Balloon dilation and open surgical revision were performed according to the conditions.ResultsForty‐six patients (58 renal units) developed postoperative hydronephrosis. The cumulative incidence was 11.4% by a median follow‐up of 59.5 months. Ureteral recurrence was detected by antegrade examinations in two patients, whereas malignant strictures were subsequently revealed in three patients. Thus, malignant etiology was found in hydronephrosis in five renal units (12.8%) of five patients (16.1%). The median times to diagnosis of hydronephrosis were 0 (interquartile range [IQR] 0–4) and 14 months (IQR 9–12) for benign and malignant strictures, respectively (p = 0.003). Of them, 31 patients (39 renal units) received interventions. Balloon dilation was performed in 13 renal units with benign strictures, and was successful in two (15.4%). Open surgical revision was performed in eight patients (11 renal units), including two with failed balloon dilation, all of which was successful.ConclusionsPostoperative hydronephrosis is potentially associated with recurrent disease. Accurate differential diagnosis is challenging although antegrade procedures may be helpful in some cases. Open surgical revision is highly effective to treat benign strictures.
Comparative study of the efficacy of fractional Er: YAG 2940 nm laser and Q‐switched Nd: YAG 1064 nm laser in keratosis pilaris
Authors: Bayazit Samet , Aşkın Özge , Kutlubay Zekayi 
Published: June 2022

AbstractBackgroundKeratosis pilaris is a common keratinization disorder of the extensor surfaces of the proximal extremities. Various treatment modalities reduce symptoms, but their efficacy is limited.AimsThe aim of this study is to compare the efficiency of Q‐Switched Nd: YAG laser and fractional Er: YAG laser.Material/MethodThe lesions in both arms were randomly divided into areas A and B. Fractional Er: YAG 2940 nm laser performed to area A 1.5 J/cm2, spot size 7 mm, frequency 3 Hz and three passes and Q‐Switched Nd: YAG 1064 nm laser performed to Area B, 4–6 J/cm2 spot size 4 mm, 8 Hz frequency, and as a single pass. Both lasers were performed in 4 sessions at 3‐week intervals. The global improvement scale evaluated treatment responses in dyspigmentation and skin texture.ResultsTwenty patients completed the study, and the mean age of a total of 20 patients was 22.9. There was no significant difference in dyspigmentation and skin texture with global improvement scale between Area A and Area B, respectively (p = 0.078, p = 0.638). In addition, there was no significant difference between patient satisfaction levels after treatment in Area A and Area B (p = 0.868).ConclusionThe efficiency of the fractional Er: YAG 2940 nm laser was found equal to the Q‐switched Nd: YAG 1064 nm laser. Fractional Er: YAG 2940 nm laser may be a new treatment option in the treatment of keratosis pilaris.
Surgical repair for deformities of the nail unit
Authors: Li Fang , Wang Xiao‐Qing , Liu Meng‐Xi , Wong Hoi‐Shiwn , Liu Zhen‐Ru , Zhou Yuan , Wang Da‐Guang 
Published: June 2022

AbstractThe nail apparatus is the largest and most complex skin appendage. Defects in this unit can result in significant functional insufficiency and cosmetic disfigurement. Common nail deformities include split nail, short nail, onycholysis, nail malalignment, hooked nail, and absent nail. Currently, surgical repair is the primary treatment for such deformities. Based on the etiological and anatomical classifications, one or more appropriate operations can be selected to repair nail unit deformities. These include autologous fat grafting, longitudinal cicatrectomy, Z‐plasties, nail bed elongation, split‐thickness sterile matrix grafting, volar V‐Y advanced flap reconstruction, sterile matrix particle grafting, germinal matrix flaps, and germinal matrix grafting. This review discusses the fundamental classification of nail unit deformities, common reconstructive surgical techniques, and their features.
Effect of three schemes of ovum pick‐up on the follicular dynamics, gene expression, and in‐vitro developmental competence of oocytes in Sahiwal cattle
Authors: Saleem Muhammad , Yousuf Muhammad Rizwan , Ghafoor Aamir , Riaz Amjad 
Published: June 2022

AbstractThis study aimed to compare the effect of three schemes of ovum pick‐up (OPU) on follicular dynamics, oocytes recovery, oocytes quality, gene expression, nuclear maturation and in‐vitro developmental competence of oocytes in Sahiwal cattle. Considering the follicle population, all the cows were divided equally in a 3 × 3 cross over design, and each cow received one of the three treatments: (a) twice weekly (TW; n = 6), (b) once weekly (OW; n = 6) and (c) bi‐weekly OPU (BW; n = 6) in three periods, with the first OPU conducted on 4, 7 and 14 days after second dominant follicle puncture (DFP) in the TW, OW and BW OPU interval groups, respectively. The collected cumulus oocytes complexes (COCs) were graded into A, B, C and D grades depending on the number of layers of cumulus cells and homogeneous nature of cytoplasm. Nuclear maturation was assessed by staining the oocytes with Hoechst 33342. The growth rate (mm/day) of dominant follicle (DF) (F1) (0.49 ± 0.21 vs. 0.71 ± 0.26 vs. 1.30 ± 0.27) and first subordinate follicle (F2) (0.85 ± 0.27 vs. 0.71 ± 0.25 vs. 1.06 ± 0.29) did not differ (p > .05) among all the three groups. The proportion of animals bearing a corpus luteum (CL) in the BW OPU interval group (53.3%) was significantly higher (p < .05) as compared to TW (13.3%) and OW (18.3%) OPU interval groups. The number of medium‐sized follicles and oocyte with grade A and B were significantly higher (p < .05) in the TW (1.16 ± 0.21 and 33.88 ± 0.03) OPU interval group as compared to the OW (0.88 ± 0.22 and 21.54 ± 0.03) and BW (0.55 ± 0.21 and 21.89 ± 0.02) OPU interval groups. However, the number of degenerated oocytes in BW (0.85 ± 0.16) OPU interval group was significantly higher (p < .05) as compared to the TW (0.16 ± 0.15) and OW (0.44 ± 0.16) OPU interval groups. Expression level of growth differentiation factor 9 in TW OPU interval group was significantly higher (p < .05) as compared to the OW and BW OPU interval groups. Likewise, expression level of bone morphogenetic protein 15 (BMP15) in the TW and BW OPU interval groups was significantly higher (p < .05) as compared to the OW OPU interval group. The nuclear maturation rate was significantly higher in the TW (63.64 ± 0.07) and BW (59.26 ± 0.08) OPU groups as compared to OW (51.43 ± 0.06) OPU interval group. However, the cleavage rate (59.30 ± 0.06 vs. 44.29 ± 0.06 vs. 56.67 ± 0.06) did not differ (p > .05) among the three groups. Whereas, the blastocyst rate tended to be higher (p = .06) in the TW (29.07 ± 0.05) and BW (28.33 ± 0.04) OPU interval groups as compared to OW (18.57 ± 0.05) OPU interval group. Taken together, it can be concluded that TW OPU interval scheme enhances the medium‐sized follicles resulting in good quality oocytes, regulates the oocyte‐derived paracrine factors, leading to higher nuclear maturation rates and improved embryonic development in‐vitro.
‘Nearly gave up on it to be honest’: Utilisation of individualised budgets by people with psychosocial disability within Australia's National Disability Insurance Scheme
Authors: Devine Alexandra , Dickinson Helen , Rangi Mediya , Huska Marie , Disney George , Yang Yi , Barney Jody , Kavanagh Anne , Bonyhady Bruce , Deane Kirsten , McAllister Ashley 
Published: June 2022

AbstractUtilisation of budgets provides important insights into the effectiveness of individualised funding schemes. Significant under‐utilisation by certain cohorts may indicate schemes are not working as intended. People with psychosocial disability have been identified as one such cohort experiencing barriers to effective budget utilisation within Australia's National Disability Insurance Scheme. Our mixed‐methods research confirms that while this cohort receive sufficient budgets, their spending is lower in comparison to other participants. Addressing under‐utilisation drivers arising from complex interactions between individual, systems, and contextual‐level factors, requires intervention within individualised funding schemes and the broader policy environment.