bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrated Approach to the Introduction of Blended Learning in Higher Education
Authors: Rajkhlina A. V. , Gromova M. V. , Kolesov R. V. 
Published: September 2022

The purpose of the article is to present the results of a study of the possibilities of an integrated approach to the introduction of blended learning in higher education. The issue of applying new forms of creating the educational process is still relevant. The pandemic has intensified the discussion around the variety of software tools and methodological techniques that are used in distance and blended learning. At the same time, the normative, technical and psychological limitations of their application remain, and the very concept of blended learning is still being refined. The article summarizes the theoretical developments on the issue of blended learning, emphasizes the relevance of the problem of its implementation, specifies the stakeholders and their positions, and formulates proposals for options for teaching in a blended format.Materials and methods: the first part of the article was written in line with a review study, namely, a quantitative analysis and comparison of the content of scientific publications on the topic under study. To prepare the second empirical part, the authors conducted a survey of students on popular options for the implementation of blended learning, the results of which were processed by systematizing the collected data, working with specialized software products, Internet sources, and graphical presentation of the results.Results. Internal and external stakeholders in the implementation of blended learning in higher education have been identified. It is emphasized that with the unity of the goal - improving the quality of the educational process - their requirements are somewhat different and form a peculiar set of tasks that should be taken into account when introducing blended learning, with the unconditional priority of the positions of a lecturer and a student. Based on the bibliometric analysis of the definition of “blended learning”, a rapid increase in the number of publications on the topic is shown, which clearly illustrates the interest of the pedagogical community. The data characterizing the opinion of students about the introduction of blended learning are given. To improve the efficiency of the educational process, it is proposed to use integrated solutions for the implementation of blended learning in higher education, taking into account the opinions of all interested parties, and above all lecturers and students.Conclusion. The results of the study contribute to the specification of directions for further work to improve the practice of introducing and using blended learning by higher education institutions.
Carboxyl Terminus of HOATZ is Intrinsically Disordered and Interacts
with Heat Shock Protein A Families
Authors: Narita Keishi , Oyama Takuji 
Published: September 2022

Background:
Hoatz is a vertebrate-specific gene, the defects of which result in
hydrocephalus and oligo-astheno-teratozoospermia in mice. It encodes a 19-kDa protein lacking any
domains of known function.

Methods:
To understand the protein activity, we purified the carboxyl-terminal fragment that is
conserved among different species, and analyzed its structure and potential binding proteins. A soluble
9.9-kDa HOATZ fragment, including a poly-histidine tag (designated HOATZ-C), was purified to
homogeneity.

Results:
The gel filtration profile and circular dichroism spectra collectively indicated that HOATZ-C
was intrinsically disordered. When HOATZ-C was mixed with cleared lysate from Hoatz-null mouse
testis, several proteins, including two of ~70 kDa size, were specifically co-purified with HOATZ-C on
a nickel column.

Conclusion:
Based on the peptide mass fingerprinting of these bands, two members of the heat-shock
protein family A were identified. These data may indicate the role of HOATZ in stress regulation in
cells characterized by motile cilia and flagella.
Developing a Provincial Surveillance and Support System for Childhood Cancer Survivors: Multiphase User-Centered Design Study
Authors: Shuldiner Jennifer , Shah Nida , Reis Catherine , Chalmers Ian , Ivers Noah , Nathan Paul 
Published: September 2022

Background
Survivors of childhood cancer are at lifelong risk of morbidity (such as new cancers or heart failure) and premature mortality due to their cancer treatment. These are termed late effects. Therefore, they require lifelong, risk-tailored surveillance. However, most adult survivors of childhood cancer do not complete recommended surveillance tests such as mammograms or echocardiograms.

Objective
In partnership with survivors, family physicians, and health system partners, we are designing a provincial support system for high-priority tests informed by principles of implementation science, behavioral science, and design thinking.

Methods
Our multiphase process was structured as follows. Step 1 consisted of a qualitative study to explore intervention components essential to accessing surveillance tests. Step 2 comprised a workshop with childhood cancer survivors, family physicians, and health system stakeholders that used the Step 1 findings and “personas” (a series of fictional but data-informed characters) to develop and tailor the intervention for different survivor groups. Step 3 consisted of intervention prototype development, and Step 4 involved iterative user testing.

Results
The qualitative study of 30 survivors and 7 family physicians found a high desire for information on surveillance for late effects. Respondents indicated that the intervention should help patients book appointments when they are due in addition to providing personalized information. Insights from the workshop included the importance of partnering with both family physicians and survivorship clinics and providing emotional support for survivors who may experience distress upon learning of their risk for late effects. In our user-testing process, prototypes went through iterations that incorporated feedback from users regarding acceptability, usability, and functionality. We sought to address the needs of survivors and physicians while balancing the capacity and infrastructure available for a lifelong intervention via our health system partners.

Conclusions
In partnership with childhood cancer survivors, family physicians, and health system partners, we elucidated the barriers and enablers to accessing guideline-recommended surveillance tests and designed a multifaceted solution that will support survivors and their family physicians. The next step is to evaluate the intervention in a pragmatic randomized controlled trial.
Pengaruh <i>Plant Growth Promoting Rhizobacteria</i> dan Mikoriza Vesikula Arbuskula terhadap Pertumbuhan Kelapa Sawit <i>Main Nursery</i> pada Kondisi Cekaman Kekeringan
Authors: Nugroho Muhammad Hady , Suryanti Sri , Umami Arif 
Published: September 2022

Cekaman Kekeringan pada bibit kelapa sawit berpengaruh pada pertumbuhan tanaman mulai dari pertumbuhan tanaman terhambat, abnormal hingga tanaman mengalami kematian. Proses peningkatan ketahanan tanaman terhadap kekeringan dapat dilakukan dengan melalui penambahan biostimulan. PGPR (Plant Growth PromotingRhizobacteria) dan MVA (Mikoriza Vesikula Arbuskula) merupakan biostimulan yang penting dalam perkebunan kelapa sawit. Penelitian bertujuan untuk mengetahui pengaruh PGPR dan MVA terhadap pertumbuhan bibit kelapa sawit di main nursery pada kondisi cekaman kekeringan. Metode penelitian menggunakan rancangan acak lengkap faktorial yang terdiri dari 2 faktor. Faktor pertama adalah mikroorganisme yang terdiri dari 1) kontrol atau tanpa mikroorganisme 2) MVA dan 3) PGPR. Faktor kedua adalah penyiraman yang meliputi penyiraman 1 hari sekali dan penyiraman 7 hari sekali, setiap perlakuan masing-masing 5 ulangan. Hasil penelitian menunjukkan bahwa perlakuan mikroorganisme dan penyiraman tidak berpengaruh nyata terhadap pertumbuhan bibit. Meskipun demikian penyiraman setiap hari dengan inokulasi MVA mampu meningkatkan volume akar.
Wireless Network Control System for Electro Stati Precipitator in Cement Plants
Authors: Marie Mehdi J. , Gaied Khalaf S. , Ajel Ahmed R. 
Published: September 2022

Wireless control networks (WCNs), based on distributed control systems of wireless sensor and actuator networks, integrate four technologies: control, computer network and wireless communications. Electrostatic precipitator (ESP) in cement plants reduces the emissions from rotary kiln by 99.8% approximately. It is an important thing to change the existing systems (wireline) to wireless because of dusty and hazardous environments. In this paper, we designed a wireless control system for ESP using Truetime 2 beta 6 simulator, depending on the mathematical model that have been built using identification toolbox of Matlab v7.1.1. We also study the effect ofusing wireless network on performance and stability of the closed loop control system. Simulation results of WCN for ESP show smooth operation with a little bit of perturbation between transient and steady state region.
Entrevista con el Dr. Héctor Zenil
Authors: Mansilla Corona Ricardo 
Published: September 2022

<p class="p2">E<span class="s2">l </span>D<span class="s2">r</span>. Z<span class="s3">e</span><span class="s2">nil </span>es un académico de amplios intereses interdisciplinarios, se describe a sí mismo como un “científico natural computacional” y de quien Gregory Chaitin ha dicho es un “nuevo tipo de teórico práctico”, parafraseando sin duda el título de la notable obra de S. Wolfram. Se graduó de matemático por la UNAM en 2003, obtuvo en 2006 una maestría en lógica por la Universidad de París I (Panthéon– Sorbonne). Más adelante, se recibió de doctor en ciencias de la computación teórica por la Universidad de Lille, en 2011, y en 2015, obtuvo el título de doctor en lógica, filosofía y epistemología de nuevo en la Universidad de París I (Panthéon–Sorbonne), con máximos honores y felicitaciones del jurado.<span class="Apple-converted-space"> </span></p>
Evaluation of Elementary School Teachers’ Knowledge about Attention Deficit Hyperactivity Disorder (ADHD)
Authors: Samir Hamed Ashwan , Hussein Ghafel Hawraa 
Published: September 2022

Objectives: This study aimed to evaluate elementary school teachers’ knowledge about Attention Deficit Hyperactivity Disorder in AL-Diwaniyah City.
Methods: A quantitative research, descriptive correlational design was used in this study, the study conducted on teachers at elementary schools in AL-Diwaniyah City from (20th September 2021 to 30th June, 2022) to evaluate of elementary school teachers knowledge about attention deficit hyperactivity disorder. The sample consist of (354) elementary school teachers were participated in the study. A non-probability sampling (convenience sample). The sample size was detected by using the sample size formula which is obtained from Steven K. Thompson, (2012). To determine the effect sample size regarding the population size.
Results: The findings indicates that 68.6% of teachers show fair level of knowledge about attention deficit hyperactivity disorders (23.90±6.989).
Conclusion: Considering the results discussion and their interpretations, the study concludes that the knowledge of the elementary school teachers in AL-Diwaniyah City at fair level regarding ADHD.
Maternal Cardiac Changes in Women With Obesity and Gestational Diabetes Mellitus
Authors: Thirunavukarasu Sharmaine , Ansari Faiza , Cubbon Richard , Forbes Karen , Bucciarelli-Ducci Chiara , Newby David E. , Dweck Marc R. , Rider Oliver J. , Valkovič Ladislav , Rodgers Christopher T. , Tyler Damian J. , Chowdhary Amrit , Jex Nicholas , Kotha Sindhoora , Morley Lara , Xue Hui , Swoboda Peter , Kellman Peter , Greenwood John P. , Plein Sven , Everett Thomas , Scott Eleanor , Levelt Eylem 
Published: September 2022

OBJECTIVE
We investigated if women with gestational diabetes mellitus (GDM) in the third trimester of pregnancy exhibit adverse cardiac alterations in myocardial energetics, function, or tissue characteristics.

RESEARCH DESIGN AND METHODS
Thirty-eight healthy, pregnant women and 30 women with GDM were recruited. Participants underwent phosphorus MRS and cardiovascular magnetic resonance for assessment of myocardial energetics (phosphocreatine [PCr] to ATP ratio), tissue characteristics, biventricular volumes and ejection fractions, left ventricular (LV) mass, global longitudinal shortening (GLS), and mitral in-flow E-wave to A-wave ratio.

RESULTS
Participants were matched for age, gestational age, and ethnicity. The following data are reported as mean ± SD. The women with GDM had higher BMI (27 ± 4 vs. 33 ± 5 kg/m2; P = 0.0001) and systolic (115 ± 11 vs. 121 ± 13 mmHg; P = 0.04) and diastolic (72 ± 7 vs. 76 ± 9 mmHg; P = 0.04) blood pressures. There was no difference in N-terminal pro-brain natriuretic peptide concentrations between the groups. The women with GDM had lower myocardial PCr to ATP ratio (2.2 ± 0.3 vs. 1.9 ± 0.4; P &lt; 0.0001), accompanied by lower LV end-diastolic volumes (76 ± 12 vs. 67 ± 11 mL/m2; P = 0.002) and higher LV mass (90 ± 13 vs. 103 ± 18 g; P = 0.001). Although ventricular ejection fractions were similar, the GLS was reduced in women with GDM (−20% ± 3% vs. −18% ± 3%; P = 0.008).

CONCLUSIONS
Despite no prior diagnosis of diabetes, women with obesity and GDM manifest impaired myocardial contractility and higher LV mass, associated with reductions in myocardial energetics in late pregnancy compared with lean women with healthy pregnancy. These findings may aid our understanding of the long-term cardiovascular risks associated with GDM.
Género y ciudadanía: una mirada desde el I Congreso Nacional Femenino Radical (Córdoba, 1949)
Authors: Spinetta Marina 
Published: September 2022

En el siguiente trabajo, se aborda el I Congreso Femenino Radical, realizado en la ciudad de Córdoba (Argentina) en 1949, como un evento que permite examinar la agenda de las mujeres radicales, iluminando aspectos sobre la organización y disputas del movimiento femenino de la Unión Cívica Radical, el principal partido opositor en el primer peronismo. La revisión de este encuentro permite repensar ese juego entre género y ciudadanía, poniendo en el centro de la escena los debates sobre los límites entre lo femenino y lo masculino, lo público y lo privado, en un momento de fuertes cambios en el orden social/ sexual, iluminados a partir de este acontecimiento. Esta reconstrucción historiográfica parte de la relectura novedosa de un corpus tradicional, conformado por la prensa local, y habilitada por las claves conceptuales indicadas, a través de una observación documental eminentemente cualitativa.
LEAP Virtual Visit Assessment (VIVA): a structured protocol for virtual visits for patients with heart failure
Authors: Gori Mauro , Bonmassari Roberto , Correale Michele , Franzini JeanMarie , Iacoviello Massimo , Dico Germano Lo , Moretti Michele , Navazio Alessandro , Pellegrini Lorenza , Volpe Marco , Senni Michele 
Published: September 2022

Abstract

Aims
Telemedicine may be of benefit in patients with heart failure (HF), although virtual visits are often carried out on an ad hoc basis. Herein, we discuss a structured protocol that defines all the steps needed for virtual visits, LEAP Virtual Visit, which includes guides and support kits for clinicians and patients.

Methods
A working group of clinicians was established to develop a protocol for virtual visits. The virtual model for monitoring HF patients was based on measurement and sizing of patient flows, type of services, and critical organizational points. The process of virtual visits was broken down to identify the specific activities, players, roles, and support tools needed for implementation in daily practice.

Results
In the protocol developed, sections were included on patient eligibility, exams, supportive tools, and practical organizational aspects. IT requirements were also considered and the most widely used teleconference platforms were compared according to features that were considered to be priority for virtual visits. Protocols and support kits were developed, including guides for clinicians and patients, two questionnaires to assess the level of satisfaction, patient diary, disease awareness brochure, and template to monitor key performance indicators. The phases include an enrolment phase, document sharing phase, pre-evaluation phase, the virtual visit itself, and the post-visit phase. The protocol for the virtual visit was divided into 8 sequential steps to be carried out between the clinic and patient/caregiver.

Conclusion
The protocol described can be expected to have a number of benefits for the patient, clinic, and healthcare structure.
Catheter ablation for treatment of bradycardia–tachycardia syndrome: is it time to consider it the therapy of choice? A systematic review and meta-analysis
Authors: Magnano Massimo , Bissolino Arianna , Budano Carlo , Abdirashid Mohamed , Devecchi Chiara , Oriente Domenico , Matta Mario , Occhetta Eraldo , Gaita Fiorenzo , Rametta Francesco 
Published: September 2022

Background
Atrial fibrillation catheter ablation (AFCA) should be considered as a strategy to avoid pacemaker (PM) implantation for patients with bradycardia–tachycardia syndrome (BTS), but lack of evidence is remarkable.

Methods
Our aim was to conduct a random-effects model meta-analysis on safety and efficacy data from controlled trials and observational studies. We compared atrial fibrillation (AF) recurrence, AF progression, procedural complication, additional procedure, cardiovascular death, cardiovascular hospitalization, heart failure and stroke in patients undergoing AFCA vs. PM implantation.

Results
PubMed/MEDLINE, Cochrane Database and Google Scholar were screened, and four retrospective studies were selected. A total of 776 patients (371 in the AFCA group, 405 in the PM group) were included. After a median follow-up of 67.5 months, lower AF recurrence [odds ratio (OR) 0.06, confidence interval (CI) 0.02–0.18, I
2 = 82.42%, P < 0.001], AF progression (OR 0.12, CI 0.06–0.26, I
2 = 0%, P < 0.001), heart failure (OR 0.12, CI 0.04–0.34, I
2 = 0%, P < 0.001), and stroke (OR 0.30, CI 0.15–0.61, I
2 = 0%, P = 0.001) were observed in the AFCA group. No differences were observed in cardiovascular death and hospitalization (OR 0.48, CI 0.10–2.28, I
2 = 0%, P = 0.358 and OR 0.43, CI 0.14–1.29, I
2 = 87.52%, P = 0.134, respectively). Higher need for additional procedures in the AFCA group was highlighted (OR 3.65, CI 1.51–8.84, I
2 = 53.75%, P < 0.001). PM implantation was avoided in 91% of BTS patients undergoing AFCA.

Conclusions
AFCA in BTS patients seems to be more effective than PM implantation in reducing AF recurrence and PM implantation may be waived in most BTS patients treated by AFCA. Need for additional procedures in AFCA patients is balanced by long-term benefit in clinical end points.
Direct oral anticoagulants for the treatment of left ventricular thrombosis: an updated systematic review and meta-analysis
Authors: Serenelli Matteo , Pavasini Rita , Vitali Francesco , Tonet Elisabetta , Cantone Anna , Di Ienno Luca , Pompei Graziella , Bertini Matteo , Campo Gianluca 
Published: September 2022

Aims
This meta-analysis aims to compare direct oral anticoagulants (DOACs) versus vitamin K antagonists (VKAs) in the setting of left ventricular thrombosis (LVT).

Method and Results
We systematically searched MEDLINE, Cochrane Library, Biomed Central and Web of Science for trials comparing DOACs versus VKAs in the setting of LVT and reporting outcome data on thrombosis resolution, stroke and bleeding. Fourteen studies were finally selected. The Mantel-Haenszel method with a random effect model was used for the pooled analysis. The primary outcome was the occurrence of LVT resolution. The secondary outcomes were the occurrence of stroke or bleeding during treatment. One thousand three hundred and thirty-two patients were included in the analysis for the primary outcome. Of these, 424 were treated with DOACs and 908 with VKAs. The pooled odds ratio (OR) for the primary outcome was 1.00 [95% confidence interval (95% CI) 0.77–1.31, I

2
0.0%], reflecting equal effect in terms of thrombus resolution. Overall, 2290 patients, 608 on DOACs and 1682 on VKAs were included in the analysis of stroke occurrence, showing reduced risk of events in patients treated with DOACs (pooled OR 0.58, 95% CI 0.36–0.93; I

2
0.0%) as well as for bleeding occurrence (number of patients included 2139; pooled OR 0.64, 95% CI 0.44–0.94; I

2
0.0%).

Conclusion
Compared with VKAs, we found DOACs to have similar efficacy on thrombus resolution and favorable effects on stroke reduction and bleedings. DOACs should be considered as an alternative treatment for LVT. Large prospective randomized clinical trials are needed to confirm this exploratory finding.
Leaching of Elements from Soil in Grassland Field Crops Treated with Raw and Acidified Slurry
Authors: Barwicki Jan , Borusiewicz Andrzej , Holden Lisa , Kulcsar Laszlo , Skibko Zbigniew , Żuchowski Ireneusz , Romaniuk Wacław 
Published: September 2022

Abstract
The state of soils was presented in the aspect of environmental protection when using acidified slurry was used as fertilizer to protect ammonia from escaping into the atmosphere. The use of concentrated sulfuric acid to lower the pH of the slurry and thus retain nitrogen in the soil and then use it by crops gives a double benefit, reduces nitrogen losses, and reduces the cost of mineral fertilizers that should be purchased. Injecting raw slurry below the surface of the soil has some benefits in the form of reducing ammonia emissions, but it does not affect the use of fertilizers with the addition of sulfur, which is ensured in the case of acidification of the slurry. Additional benefit is to obtain environment protection. Leaching of elements from grassland and corn crop soil treated with raw cattle slurry and acidified cattle slurry (m3·ha−1) was presented. The K content was highest in the leachate collected after the application of the last batch of acidified slurry. Yield tests were conducted on similar soils as presented in the tables for grass, using six 500 m2 plots with corn, cultivar ES Cirrus, with acidified slurry and one test plot with non-acidified slurry. Analysis of variance and significant difference among the treatment means were separated using Duncan’s Multiple Range Test (DMRT) at a probability level of 0.05. Based on statistical analysis, it was demonstrated that crop yields of corn grain increased when fertilized with acidified slurry, at an average of 4 t·ha−1. During field tests corn crop yield varied from 14 t·ha−1 to 18 t·ha−1 when non-acidified and acidified slurry were used. The yield on the grassland was approx. 30 t·ha−1. The soil sorption complex, in combination with its buffer properties and acidification, did not affected the pH value. This makes the acidification process safe for plants and for the soil environment.
Temporary international migration, shocks and informal finance: analysis using panel data
Authors: Chakraborty Tanika , Pandey Manish 
Published: September 2022

Abstract
We examine households’ temporary international migration response when faced with shocks in rural Kyrgyzstan. Using a household fixed effects model, we find that while a drought shock increases migration, a winter shock reduces migration. We argue that this difference is because of the trade-off between two effects of a shock for a household: loss of income and increase in the need for labor services. Migration increases when the former effect of a shock dominates and it reduces when the latter effect dominates. We explore these mechanisms further, and find that when households have easier access to informal finance the migration response is muted only for shocks for which the adverse income effect dominates. These findings provide evidence in favor of our proposed mechanisms through which shocks affect migration.