bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Economic And National Identity Loss Messages, And The Moderating Effect of Political Orientation, On Climate Change Policy Support
Authors: Klas Anna , C Edward J.R. , Fielding Kelly , Mackay Matthew , Lohmann Susanne , Ling Mathew 
Published: January 2022

Abstract
As climate change continues to be politically divisive, developing communications that align with right-leaning beliefs may increase bipartisan support for climate policy. In two experimental studies (Study 1, Australia, N = 558; Study 2, United States, N = 859), we tested whether an economic loss or national identity loss message would elicit greater support for mitigation and adaptation policies when compared to one another and to a control message. We also tested whether the direct effects of these message types were conditional on political orientation (specifically, identifying as politically right-leaning). In both studies, preliminary analyses indicated that the message manipulations were effective and that there was a high level of support for both types of climate policy. When compared to left-wing adherents, those who were politically right-leaning were less likely to support mitigation and adaptation policies in either sample. Australian (Study 1) identification – although not American identity (Study 2) – also uniquely predicted adaptation support (but not mitigation support). Yet, there were no significant message frame or interaction effects in the Australian (Study 1) or U.S. sample (Study 2). This suggests that neither an economic loss nor national identity loss message frame may be effective in overcoming the political polarization of climate change in Australia or the United States. Nevertheless, national identity could still play a useful role in Australian climate communications given its positive relationship to adaptation policy support, and therefore warrants further investigation.
The Excitability of Ipsilateral Motor Evoked Potentials Is Not Task-specific and Spatially Distinct From the Contralateral Motor Hotspot
Authors: Seusing Nelly , Strauss Sebastian , Fleischmann Robert , Nafz Christina , Groppa Sergiu , Muthuraman Muthuraman , Byblow Winston D. , Lotze Martin , Grothe Matthias 
Published: January 2022

Abstract

ObjectiveThe role of ipsilateral descending motor pathways in voluntary movement of humans is still a matter of debate. Few studies have examined the task dependent modulation of ipsilateral motor evoked potentials (iMEPs). Here, we determined the location of upper limb biceps brachii (BB) representation within the ipsilateral primary motor cortex. MethodsMR-navigated transcranial magnetic stimulation mapping of the dominant hemisphere was undertaken with twenty healthy participants who made tonic unilateral, bilateral homologous or bilateral antagonistic elbow flexion-extension voluntary contractions. Map center of gravity (CoG) and area for each BB were obtained. ResultsThe map CoG of the ipsilateral BB was located more anterior-laterally than those of the contralateral BB within the primary motor cortex. However different tasks had no effect on either the iMEP CoG location or the size. ConclusionOur data suggests that ipsilateral and contralateral MEP might originate in distinct adjacent neural populations in the primary motor cortex, independent of task dependence.
Artificial Neural Network Potentials for Mechanics and Fracture Dynamics of Materials
Authors: Jung Gang Seob , Myung Hoon Joo , Irle Stephan 
Published: January 2022

Abstract
Atomistic understanding of mechanics and failure of materials is the key for engineering and applications. Modeling accurately brittle failure with crack propagation in covalent crystals requires a quantum mechanics-based description of individual bond-breaking events for large system sizes. Machine Learned (ML) potentials have emerged to overcome the traditional, physics-based modeling tradeoff between accuracy and accessible time and length scales. Previous studies have shown successful applications of ML potentials for describing the structure and dynamics of molecular systems and amorphous or liquid phases of materials. However, their application to deformation and failure processes in materials is yet uncommon. In this study, we discuss apparent limitations of ML potentials to describe deformation and fracture under loadings and propose a way to generate and select training data for their employment in simulations of deformation and fracture of crystals. We applied the proposed approach to 2D crystal graphene, utilizing the density-functional tight-binding (DFTB) method for more efficient and extensive data generation in place of density functional theory (DFT). Then, we explore how the data selection affects the accuracy of the developed artificial neural network potential (NNP), indicating that only the errors in total energies and atomic forces are insufficient to judge the NNP’s reliability. Therefore, we evaluate and select NNPs based on their performance in describing physical properties, e.g., stress-strain curves and geometric deformation. In sharp contrast to popular reactive bond order potentials, our optimized NNP predicts straight crack propagation in graphene along both armchair and zigzag lattice directions, as well as higher fracture toughness of zigzag edge direction. Our study provides significant insight into crack propagation mechanisms at atomic scales and highlights strategies for NNP developments of broader materials.
Drivers of Disparities in Stage at Diagnosis Among Women With Breast Cancer: South African Breast Cancers and HIV Outcomes Cohort
Authors: Mapanga Witness , Norris Shane A , Craig Ashleigh , Ayeni Oluwatosin A. , Chen Wenlong C. , Jacobson Judith S. , Neugut Alfred I. , Ruff Paul , Cubasch Herbert , O’Neil Daniel S. , Buccimazza Ines , Čačala Sharon , Stopforth Laura W. , Farrow Hayley A. , Nietz Sarah , Phakathi Boitumelo , Chirwa Tobias , McCormack Valerie A. , Joffe Maureen 
Published: January 2022

Abstract
Objective In low- and middle-income countries (LMICs), advanced stage diagnosis of breast cancer (BC) is common, and this contributes to poor survival. By understanding the determinants of the stage at diagnosis will aid in designing interventions to downstage disease and improve survival from BC in LMICs. MethodsWithin the South African Breast Cancers and HIV Outcomes (SABCHO) cohort, we examined factors affecting the stage at diagnosis of histologically confirmed invasive breast cancer at five tertiary hospitals in South Africa. The stage was assessed clinically. To examine the associations of the health system, socio-economic/household and individual factors, hierarchical multivariate logistic regression with odds of late-stage at diagnosis (stage III-IV), was used. Results The majority (59%) of the included 3497 women were diagnosed with late-stage BC disease (59%). The effect of health system-level factors on late-stage BC diagnosis was consistent and significant even when adjusted for both socio-economic- and individual-level factors. Women diagnosed in a tertiary hospital that predominantly serves a rural population were almost 3 times (OR=2.89 (95% CI: 1.40-5.97) likely to be associated with late-stage BC diagnosis when compared to those diagnosed at a hospital that predominantly serves an urban population. Taking more than 3 months from identifying the BC problem to first health system entry (OR=1.66 (95% CI: 1.38–2.00)), and receptor subtypes [luminal B (OR=1.49 (95% CI: 1.19–1.87)), HER2 enriched (OR=1.64 (95% CI: 1.16–2.32))] were associated with a late-stage diagnosis. Whilst having a higher socio-economic level (a wealth index of 5) reduced the probability of late-stage BC, OR=0.64 (95% CI: 0.47 – 0.85). ConclusionAdvanced stage diagnosis of BC among women in SA who access health services through the public health system was associated with both modifiable health system-level factors and non-modifiable individual-level factors. These may be considered as elements in interventions to reduce the time to diagnosis of breast cancer in women.
Barriers to and Facilitators of Accessing HIV Services for Street-Involved Youth in Canada and Kenya
Authors: Khan Momina , MacEntee Katie , Kiptui Reuben , Berkum Amy , Oudshoorn Abe , Ayuku David O , Lee Edward Ou Jin , Abramovich Alex , MacDonald Sue-Ann , Braitstein Paula , Apondi Edith 
Published: January 2022

Abstract
Introduction: UNICEF estimates that there are as many as 100 million street-involved youth (SIY) globally. Marginalized conditions put SIY at higher risk of HIV and adverse outcomes once HIV-positive. The objective of this analysis was to describe barriers and facilitators of accessing HIV prevention, testing, and treatment services as Phase I of an implementation study evaluating the use of Peer Navigators to increase access to HIV services.Methods: Semi-structured interviews, focus group discussions (FGD), and Theatre Testing were conducted with individuals who identify as SIY, health care providers, and community stakeholders living in Canada (Toronto, Montreal, London) and Kenya (Eldoret, Huruma, Kitale). Data were analyzed using a directed content approach, guided by the socio-ecological model (SEM).Results: Across the six sites were 195 participants: 64 SIY, 42 healthcare providers, and 97 community-based stakeholders. Barriers were identified at the societal (e.g. intersectional stigma and discrimination), public policy (e.g., inadequate access to basic needs, legal documentation, lack of health insurance, and limited community-based funding), institutional (e.g. lack of inclusive education and training, inadequate HIV educational outreach, and restrictive service provision), interpersonal (e.g., ineffective communication from healthcare providers), and intrapersonal levels (e.g. lack of trust and associated fear, low perception for healthcare, and lack of self-esteem). These contributed to limited HIV services utilization among SIY. Conversely, numerous facilitators were also identified at the public policy (e.g. affordable HIV services and treatment), institutional (e.g. available and accessible HIV prevention tools, HIV education and awareness programs, and holistic models of care), interpersonal level (e.g., systems navigation support, peer support, and personal relationships), and intrapersonal levels (e.g. self-efficacy) as positively supporting SIY access to HIV services.Conclusions: Intersectional stigma was a critical barrier in all sites, and policies and programs that foster welcoming environments for youth from diverse backgrounds and living circumstances may be better able to respond to the HIV service needs of this high risk population. Social support and navigation services were reported to facilitate access to HIV services in all sites.
HPLC and high-throughput sequencing revealed differences of tea-leaves quality components and soil microbial community structure between modern and ancient tea plantations in Lincang Region
Authors: Yang Guangrong , Zhou Dapeng , Wan Renyuan , Wang Conglian , Xie Jin , Ma Cunqiang , Li Yongmei 
Published: January 2022

Abstract
BackgroundAncient tea plantations with an age over 100 years still reserved at Mengku Town in Lincang Region of Yunan Province, China. However, the characteristic of soil chemicophysical properties and microbial ecosystem in the ancient tea plantations and their impact on tea-leaves chemical components remained unclear. Tea-leaves chemical components including amino acids, phenolic compounds and purine alkaloids, and soil chemicophysical properties including pH, cation exchange capacity (CEC), soil organic matter (SOM), soil organic carbon (SOC), total total nitrogen (TN), total phosphorus (TP), total potassium (TK), alkali-hydrolyzable nitrogen (AN), available phosphorous (AP) and available potassium (AK), and microbial community structure of modern and ancient tea plantations in five geographic sites (i.e. Bingdao, Baqishan, Banuo, Dongguo and Jiulong) were determined by high performance liquid chromatography (HPLC) and high-throughput sequencing, respectively. ResultsTea-leaves chemical components, soil chemicophysical properties and microbial community structures including bacterial and fungal community abundance and diversity evaluated by Chao 1 and Shannon varied with geographic location and tea plantation type. The ancient tea plantations possessed significantly (P<0.05) higher free amino acids, gallic acid, caffeine and EGC in tea-leaves, as well as soil fertility. The bacterial community structure kept stable, while fungal community abundance and diversity significantly (P<0.05) increased in ancient tea plantation because of higher soil fertility and lower pH. The long-term plantation in natural cultivation way significantly (P<0.05) improved the abundances of Nitrospirota, Methylomirabilota, Ascomycota and Mortierellomycota phyla. ConclusionsDue to the natural cultivation way, the ancient tea plantations still maintained relatively higher soil fertility and complete soil microbial ecosystem, which contributed to the sustainable development with higher quality in tea-leaves.
Effects of an Internationalization at Home (IAH) Programme on Cultural Awareness among Medical and Nursing Students in Hong Kong and Indonesia During the COVID-19 Pandemic: A Mixed-Methods Study
Authors: KOR Patrick Pui Kin , YU Clare , TRIASTUTI Ida ayu , SIGILIPOE Mitra Andini , KRISTIYANTO Haryo Dimasto , PRATIWI Johana Puspasari Dwi , PERDAMAIAN Teguh Kristian , LI Mengli Lisa , PANG Phyllis , WIDAGDO Maria Meiwati 
Published: January 2022

Abstract
Background: The COVID-19 pandemic has severely impacted the learning experience of students by limiting their opportunities for face-to-face intercultural exchanges. Given the importance of cultural competence in medical education, there is a need to develop a programme that promotes cultural awareness, but that offers more flexibility in terms of outbound mobility. This study aims to evaluate the effectiveness of an internationalization at home programme and to explore the learning experiences of medical and nursing students from Hong Kong and Indonesia. Methods: Students were recruited from two universities in Hong Kong and Indonesia. They attended an online internationalization at home programme designed by members of the research team from both countries. A mixed-methods study was conducted. A pre-test post-test design was used to evaluate the effects of the programme on cultural awareness, and four focus group interviews were conducted to explore the students’ experiences in the programme. Quantitative and qualitative data were analysed by T-test and thematic analysis. Data were integrated via triangulation. Results: One hundred and forty-eight students from Hong Kong and Indonesia participated in the study. After the programme, there was a significant improvement in cultural awareness. Three themes were identified: (1) learning process: enjoyable, but a desire remains for face-to-face cross-cultural communication; (2) learning outcomes: gained cultural awareness, developed cultural sensitivity, had an opportunity to practice language and learn about new learning styles; (3) factors influencing learning outcomes: facilitators (micro-movie and active communication) and barriers (language barrier, inappropriate time arrangement, insufficient prior briefing). Conclusion: This programme achieved the learning outcomes by successfully enhancing the cultural awareness of students during a time of pandemic when outbound student exchanges were not possible. Further adaptations of the programme are required to further enhance learning outcomes.
The Correlation of Papanicolaou Smears and Clinical Features to Identify the Common Risk Factors for Cervical Cancer: a Retrospective and Descriptive Study From a Tertiary Care Hospital in Trinidad
Authors: Umakanthan Srikanth , Ghany Saudah , Gay La Donna , Gilkes Tia , Freeman Jamila , Francis Andre , Francis Kyle , Gajadhar Gabriel , Fraser Junea 
Published: January 2022

Abstract
Background: Cervical cancer, the fourth most frequent cancer in women, is associated with the human papilloma virus (HPV). This study focuses on identifying any risk factors and clinical findings for abnormal cervical cytology and histopathology in relation to the Trinidad and Tobago population. Some risk factors include early age of first coitus, high number of sexual partners, high parity, smoking, and use of certain medications such as oral contraception. This study is aimed to identify the significance of Papanicolaou (pap) smears and to identify the common risk factors that contribute to the development of premalignant and malignant cervical lesions. Method: A three-year retrospective, descriptive study of cervical cancer was conducted at the Eric Williams Medical Sciences Complex to assess the risk factors and clinical findings using cervical cytology and histopathology data of patients with premalignant lesions. The subject population included 215 female patients aged 18 years and older who had the following documented abnormal cervical cytology: (ASCUS), ASC-H, LSIL, HSIL, Atypical Glandular cells, HPV, Adenocarcinoma, Invasive Squamous Cell Carcinoma. Histopathology records were analysed for thirty-three of these patients. Patients’ information were recorded on data collection sheets adapted from the North Central Regional Health Authority’s cytology laboratory standardised reporting format request form (Appendix I). Results and findings: The data were analysed via Statistical Package for Social Sciences (SPSS) software edition 23 using frequency tables and descriptive analysis. The sample mean age of the population was 36.7 years, first age of coitus was 18.1 years, number of sexual partners was 3.8 and number of live births was 2. LSIL was the most popular abnormal finding, 32.6 %, followed by HSIL, 28.8% and ASCUS, 27.4%. Most histopathological reports resulted in CIN I and II.Conclusion: The major risk factors observed for cytology abnormalities and premalignant lesions were early age of coitus, high number of sexual partners, and no use of contraception.Patients mostly presented as asymptomatic despite obtaining abnormal cytology results. Hence, regular pap smear screening should continue to be highly encouraged.
A Baseline Survey of The Geochemical Characteristics of the Arctic Soils of Alexandra Land Within the Franz Josef Land Archipelago (Russia)
Authors: Moskovchenko Dmitry Valerievich , Babkin Evgeny , Pogojeva Maria , Zhostkov Ruslan , Ovsyuchenko Aleksandr , Sysolyatin Robert 
Published: January 2022

Abstract
The composition of soils and their parent materials were studied within one of the most northern land areas of the world – the island of Alexandra Land of the Franz Josef Land archipelago. Contents of 65 trace and major elements were determined using atomic emission spectrometry (ICP-AES) и inductively coupled plasma spectrometry (ICP-MS). Other analyzed characteristics included soil pH, particle-size distribution and contents of carbon and nitrogen. The mineralogical composition of rocks was determined in thin sections. The studied soils were formed on basalts with high contents of MgO, Fe2O3, TiO2, Сu, Co, V, Ni, Cr, Zn, and low contents of Pb and Hg. The composition of soils was generally similar to that of the bedrock. The median concentrations (mg kg-1) of trace elements in the soils were as follows: Cu - 160, Zn - 101, Ni - 74, Pb - 2.9, Cd - 0.14, and Hg - 0.031. The bedrock had an alkaline pH, whereas the soil pH ranged from weakly acid to alkaline. The textural class of the soils predominantly corresponded to sandy loam. The contents of clay and silt increased with depth due to the migration of these fractions with groundwater. The concentrations of ecologically hazardous Hg and Pb were slightly increased in the upper layer of soils and correlated with carbon contents, which was indicative of bioconcentration processes.
SARS-CoV-2 Slows Brain Rhythms with more Severe Effects in Younger Individuals
Authors: Saab Carl , Valsamis Helen , Baki Samah , Leung Jason , Ghosn Samer , Lapin Brittany , Chari Geetha , Rasheed Izad-Yar , Park Jaehan , Punia Vineet , Nair Dileep , Kaniecki Ann Marie , Edhi Muhammad 
Published: January 2022

Abstract
Coronavirus disease secondary to infection by SARS-CoV-2 (COVID19 or C19) causes respiratory illness, as well as severe neurological symptoms that have not been fully characterized. In a previous study, we developed a computational pipeline for the automated, rapid, high-throughput and objective analysis of brain encephalography (EEG) rhythms. In this retrospective study, we used this pipeline to define the quantitative EEG changes in patients with a PCR-positive diagnosis of C19 (n=31) in the intensive care unit (ICU) of Cleveland Clinic, compared to a group of age-matched PCR-negative (n=38) control patients in the same ICU setting. Qualitative assessment of EEG by two independent teams of electroencephalographers confirmed prior reports with regards to the high prevalence of diffuse encephalopathy in C19 patients, although the diagnosis of encephalopathy was inconsistent between teams. Quantitative analysis of EEG showed distinct slowing of brain rhythms in C19 patients compared to control (enhanced delta power and attenuated alpha-beta power). Surprisingly, these C19-related changes in EEG power were more prominent in patients below age 70. Moreover, machine learning algorithms showed consistently higher accuracy in the binary classification of patients as C19 versus control using EEG power for subjects below age 70 compared to older ones, providing further evidence for the more severe impact of SARS-CoV-2 on brain rhythms in younger individuals irrespective of PCR diagnosis or symptomatology, and raising concerns over potential long-term effects of C19 on brain physiology in the adult population and the utility of EEG monitoring in C19 patients.
Microbial healing of nature-like rough sandstone fractures for rock weathering mitigation
Authors: Dong Zhi-Hao , Pan Xiaohua , Tang Chao-Sheng , Shi Bin 
Published: January 2022

Abstract
Rock weathering fractures in nature are complex and fracture healing is an effective strategy for rock weathering mitigation. This study is a first attempt to apply microbially induced calcium carbonate precipitation (MICP) technology in the healing of nature-weathering-like rough fractures (NWLRF). Sandstone was studied as an example due to it is a wide-spread construction, sculpture and monuments material all over the world. In order to achieve a high healing efficiency, a repeated mixture injection strategy was proposed. Based on a series of laboratory MICP injection experiments on four types of NWLRF, we systematically explored the fundamental micro-healing mechanism and the influence of factors including fracture aperture, characteristics of branch fractures, and cementation solution concentration. Experimental results demonstrated that MICP healing with the repeated mixture injection strategy had the ability to efficiently heal the penetrated NWLRF well with length in centimeter-scale and aperture in millimeter-scale, but cannot heal the non-penetrated branch fractures under low injection pressure. The repeated mixture injection strategy furtherly achieved a high apparent fracture healing ratio and a significant reduction of transmissivity. The apparent fracture healing ratios of all main fractures were higher than 80% and the maximum was 99.1%. Fracture transmissivity was reduced by at least three orders of magnitude from about 1×10-4 m2/s to less than 1×10-7 m2/s, and the highest reduction reached to four orders. For the aspect of the effects, larger cementation solution concentration, finer aperture and the existing of penetrated branch fracture were beneficial to improve the healing effect. Moreover, the MICP healing mechanism with high fracture healing ratio and significant reduction of transmissivity on sandstone NWLRF was also analyzed. The research results have important theoretical significance and technical guidance value for the disaster prevention and mitigation of rock weathering.