bluuebunny/crossref_metadata_2025_split huggingface dataset:
Women With Psoriatic Arthritis Experience Higher Disease Burden Than Men: Findings From a Real-World Survey in the United States and Europe
Authors: Gossec Laure , Walsh Jessica A. , Michaud Kaleb , Peterson Steve , Holdsworth Elizabeth A. , Karyekar Chetan S. , Booth Nicola , Chakravarty Soumya D. , Ogdie Alexis 
Published: August 2022

ObjectiveAlthough psoriatic arthritis (PsA) is equally present in men and women, sex may influence clinical manifestations and the impact of disease on patients’ lives. This study assessed differences in clinical characteristics, disability, quality of life (QOL), and work productivity by sex in real-world practice.MethodsA cross-sectional survey of rheumatologists/dermatologists and their patients with PsA was conducted in France, Germany, Italy, Spain, the United Kingdom, and the United States between June and August 2018. Data collected included demographics, treatment use, clinical characteristics (tender joint count, swollen joint count, body surface area affected by psoriasis), QOL (EuroQoL 5-Dimension questionnaire [EQ-5D], Psoriatic Arthritis Impact of Disease [PsAID12]), disability (Health Assessment Questionnaire–Disability Index [HAQ-DI]), and work productivity (Work Productivity and Impairment Index [WPAI]). Outcomes were compared between men and women using parametric and nonparametric tests, as appropriate.ResultsOf 2270 patients (mean age 48.6 [SD 13.3] yrs, mean disease duration 4.9 [SD 6.0] yrs), 1047 (46.1%) were women. Disease duration, disease presentation, and biologic use (mean 54.2%) were comparable between women and men. Women reported worse QOL (EQ-5D: 0.80 [SD 0.2] vs 0.82 [SD 0.2];P= 0.02), greater disability (HAQ-DI: 0.56 [SD 0.6] vs 0.41 [SD 0.5];P< 0.01) and work activity impairment (WPAI: 27.9% [SD 22.0] vs 24.6% [SD 22.4];P< 0.01) than men. However, women had a lower burden of comorbidities (Charlson Comorbidity Index: 1.10 [SD 0.5] vs 1.15 [SD 0.6];P< 0.01).ConclusionIn patients with similar PsA disease activity and treatment, women experienced greater disease impact than men. This represents a significant consideration for the therapeutic management of PsA.
A Retrospective Analysis of Outcome in Melanoma Differentiation–Associated Gene 5–Related Interstitial Lung Disease Treated with Tofacitinib or Tacrolimus
Authors: Fan Li , Lyu Wenting , Liu Huarui , Jiang Hanyi , Chen Lulu , Liu Yin , Zhuang Yi , Huang Mei , Cao Min , Cai Hourong , Xiao Yonglong , Dai Jinghong 
Published: August 2022

ObjectiveThe efficacy of tofacitinib (TOF) in the early diagnosis of melanoma differentiation–associated gene 5 (MDA5)–related interstitial lung disease (ILD) has been described. However, whether TOF exposure is associated with a reduced 1-year mortality rate remains undetermined.MethodsPatients diagnosed with MDA5-ILD receiving TOF or tacrolimus (TAC) treatment were included. A Cox proportional hazards model, which was adjusted for age, sex, smoking history, anti-MDA5 antibody titers, and concurrent use of other steroid-sparing agents, was performed to compare all-cause mortality and to investigate the risk factors predicting 1-year mortality rates in the 2 treatment groups.ResultsDuring the study period, 26 patients were treated with TOF and 35 were treated with TAC. The 6-month (38.5% vs 62.9%;P= 0.03) and 1-year (44.0% vs 65.7%;P= 0.03) mortality rates in the TOF group were significantly lower than those in the TAC group. There were 13 patients diagnosed with rapidly progressive ILD (RP-ILD) in the TOF group and 22 in the TAC group. The majority of deaths occurred in patients with RP-ILD. The 6-month (76.9% vs 95.5%;P= 0.02) and 1-year (84.6% vs 100.0%;P= 0.02) mortality rates of patients with RP-ILD in the TOF group were also lower than those in the TAC group, respectively. The adjusted model showed that TOF exposure was associated with a lower risk for 1-year mortality (hazard ratio 0.44, 95% CI 0.20-0.96;P= 0.04). However, the incidence of adverse events (73.1% vs 74.3%;P> 0.99) and medication discontinuation rates (23.1% vs 14.3%;P= 0.50) in the TOF and TAC groups were similar, respectively.ConclusionOur observational study showed that TOF use might have a potential effect on improving the outcomes of MDA5-ILD. Future clinical trials are needed to assess the long-term efficacy and tolerability of TOF.
Facemask Literacy and usage during the COVID-19 Pandemic: A Study among Employees of the University of Colombo, Sri Lanka during July-August 2021
Authors: Majeed S. , Atapattu P. M. , Fernando A. D. A. , Wasalathanthri S. 
Published: August 2022

Background: Correct facemask usage and disposal is crucial to prevent COVID-19 infection spread and environmental pollution.
Objectives: To assess the knowledge and practises on facemask usage among the employees of University of Colombo during the COVID-19 pandemic.
Methods: Web-based, descriptive cross-sectional study was conducted among the employees of University of Colombo using a pre-tested, self-administered questionnaire.
Results: All 208 respondents (female: male=33:19) always wore facemasks outside home. Majority preferred KN-95 (70%)/ surgical masks (64%) over cloth masks (3%). Most (81%) wore double masks, but only 14% practiced double masking as per Centre for disease control and prevention (CDC) recommendation. Only 70% wore facemasks at workplace, 50% inside public transport, 51% at home when outsiders were present and 28% when family members had respiratory symptoms. Removing /lowering facemasks in washrooms (19%), with 1m distancing (7%) or when answering phones (3%) was reported in public places. Main problems included difficulty in breathing (59%), feeling hot (50%), spectacle fogging (42%), and ear pain (42%). Majority disposed facemasks by burning (46%) or with other garbage (38%), highlighting the lack of a proper disposal system. High scores for knowledge (≥3) and usage patterns (≥4) were found in 93.3% and 68.7% respectively. Females had a higher statistically significant (p<0.05) knowledge on face masks. Correct usage of facemasks was significantly higher (p<0.05) among academics and employees with a higher educational level.
Conclusion: Though the majority adhered to the correct usage of facemasks, some unsatisfactory practises were evident, which require prompt intervention to optimise the desired outcomes. Reinforcing education on the literacy and use of facemasks and developing methods for disposal are immediate necessities.
Basophil Depletion Alters Host Immunity, Intestinal Permeability, and Mammalian Host-to-Mosquito Transmission in Malaria
Authors: Donnelly Erinn L , Céspedes Nora , Hansten Gretchen , Wagers Delaney , Briggs Anna M , Lowder Casey , Schauer Joseph , Garrison Sarah M , Haapanen Lori , Van de Water Judy , Luckhart Shirley 
Published: August 2022

Abstract
Malaria-induced bacteremia has been shown to result from intestinal mast cell (MC) activation. The appearance of MCs in the ileum and increased intestinal permeability to enteric bacteria are preceded by an early Th2-biased host immune response to infection, characterized by the appearance of IL-4, IL-10, mast cell protease (Mcpt)1 and Mcpt4, and increased circulating basophils and eosinophils. Given the functional similarities of basophils and MCs in the context of allergic inflammation and the capacity of basophils to produce large amounts of IL-4, we sought to define the role of basophils in increased intestinal permeability, in MC influx, and in the development of bacteremia in the context of malaria. Upon infection with nonlethal Plasmodium yoelii yoelii 17XNL, Basoph8 × ROSA-DTα mice or baso (−) mice that lack basophils exhibited increased intestinal permeability and increased ileal MC numbers, without any increase in bacterial 16S ribosomal DNA copy numbers in the blood, relative to baso (+) mice. Analysis of cytokines, chemokines, and MC-associated factors in the ileum revealed significantly increased TNF-α and IL-13 at day 6 postinfection in baso (−) mice compared with baso (+) mice. Moreover, network analysis of significantly correlated host immune factors revealed profound differences between baso (−) and baso (+) mice following infection in both systemic and ileal responses to parasites and translocated bacteria. Finally, basophil depletion was associated with significantly increased gametocytemia and parasite transmission to Anopheles mosquitoes, suggesting that basophils play a previously undescribed role in controlling gametocytemia and, in turn, mammalian host-to-mosquito parasite transmission.
impact of cubism graft on the outcome of tympanoplasty surgery
Authors: Mahmoud Belal Mahmoud Abdelrahman , Fathalla Mohamed Abdelkawy , Elsheikh Ahmed Mohamed Abdel Hady , Abdelazim Mohamed Hussein 
Published: August 2022

Background: Tympanoplasty is a widely performed surgery for the repair of tympanic membrane perforation. Aim of the study: to compare the auditory and anatomical outcomes between two different techniques in tympanoplasty: the first with temporalis facia graft + the new “cubism” graft and the other with temporalis facia graft alone. Patients and methods: A prospective, randomized study was conducted in Otorhinolaryngology Head and Neck Surgery Department, Al-Azhar University Hospital (Damietta). Results: Cubism graft group wasn't significantly different to Temporalis fascia only group regarding ABG (p= 0.233). The ABG gain 3 month in Cubism graft group ranged from 14 to 17.5 with mean ± SD = 16.17 ± 1.15 while in Temporalis fascia only group the ABG gain 3 month ranged from 10 to 16 with mean ± SD = 14.12 ± 1.91 with statistical significant difference (p= 0.005) between the two groups. Conclusion: The novel “cubism” graft technique offers many advantages. Cartilage grafts can be thinned harmlessly while obtaining a convenient additional material in this technique. This hybrid, cartilaginous dust and PRF mixture graft can be used widely in tympanoplasty. We experienced that both functional and anatomical outcomes of this graft are very satisfying.
CERTIDÃO DE NASCIMENTO: a redução sociológica em seu contexto de publicação
Authors: Bariani Edison 
Published: August 2022

Decorrido mais de meio século desde a publicação de A redução sociológica, de Alberto Guerreiro Ramos, o livro continua sendo um marco das ciências sociais, principalmente da sociologia no Brasil. Entretanto, cabe ainda lançar alguma luz sobre o contexto social e o contexto intelectual no qual a obra foi produzida, bem como sua recepção crítica naquele momento. Também, restam ainda alguns aspectos a serem analisados a partir da perspectiva atual, ou seja, um balanço e revisão da importância desta obra na cultura brasileira, do que já acusa a ação do tempo e do que permanece atual e mesmo do ainda não foi devidamente analisado.Palavras-chave : Guerreiro Ramos; Redução Sociológica; Periferia; Recepção; Sociologia Brasileira. Birth certificate: sociological reduction in its publishing context Edison BarianiMore than half a century after the publication of Alberto Guerreiro Ramos’s “The Sociological Reduction”, it is still a milestone in social sciences, especially for sociology in Brazil. However, some things still must be made clear on the social and intellectual context in which the work was produced, as well as its critical reception in that moment. There are also some aspects to be analyzed from the current perspective, that is, a review must be made of the importance of this work in Brazilian culture and what parts are out of touch and what parts remain relevant nowadays.Palavras-chave : Guerreiro Ramos; Sociological Reduction; Periphery; Reception; Brazilian Sociology.Extrait de naissance: la réduction sociologique dans le contexte de sa publication Edison BarianiPlus d’un demi siècle après la publication de “La réduction sociologique” de Alberto Guerreiro Ramos, ce livre est toujours une référence pour les sciences sociales et surtout pour la sociologie au Brésil. Cependant il est nécessaire de mieux expliquer le contexte social et intellectuel dans lequel l’oeuvre a été écrite ainsi que la critique dont elle a été l’objet à l’époque. Mais certains aspects doivent encore être analysés dans une perspective actuelle, en d’autres termes, il est nécessaire de faire un bilan et une révision de l’importance de cette oeuvre dans la culture brésilienne en tenant compte de l’action du temps et de ce qui reste actuel voire de ce qui n’a pas encore été dûment analysé.Palavras-chave : Guerreiro Ramos; Réduction Sociologique; Périphérie; Réception; Sociologie Brésilienne. Publicação Online do Caderno CRH no Scielo: http://www.scielo.br/ccrh Publicação Online do Caderno CRH: http://www.cadernocrh.ufba.br
فاعلية الحوار في قصص جمال نوري - دراسة تحليلية
Authors: محمد ندى حسن 
Published: August 2022

يعد الحوار أحد الآليات التي تعتمدها القصة في بناء تشكيلها السردي بجانب آلية السرد والوصف، وله تأثير بالغ الأهمية في البناء العام للقصة على مستويات كثيرة ، ومن هنا تتأكد العلاقة الدرامية السردية لآلية الحوار في العمل السردي القصصي ، حيث يظلّ ذا حمولة درامية دائما حتى وإن اشتغل في اي حقل من حقول السرد المعروفه ، وبالنظر لأهمية الحوار في السرد كونه يحقق وظائف عدّه منها تصوير الشخصية وتطوير الاحداث وتقديم الجو أو الحالة سعى البحث لتوضيح دور الحوار في القصة متخذاً من قصص الكاتب جمال نوري إنموذجا يجسد ذلك ، قام البحث على مدخل ومبحثين تضمن المدخل تحديد مفهوم الحوار ووظائفه في العمل القصصي ، وخص المبحث الأول لدراسة (الحوار الخارجي) من حيث الحوار المركب ، والحوار الترميزي ،والحوار المجرد في حين خص المبحث الثاني بدراسة (الحوار الداخلي) من حيث المونولوج ، والمناجاة والارتجاع الفني.وفيها توصل البحث الى إن القاص لدية تنوع في حواراتة القصصية، كما انه يميل الى الحوارات الداخلية على الاغلب قد تكون الغاية منها ولوج القارئ وتعمقه في ثنايا نصوصه القصصية من اجل الوصول الى تفكير الكاتب وهدفه منها، ويتحدث داخل القصة وكأنه واحد من شخصيات القصة يعيش أحداثها وهذا يدل على مدى تفاعلة وانسجامه مع شخصياته. Dialogue is one of the mechanisms adopted by the story in the building formed the narrative side of narrative and description mechanism, and has a major impact important in the construction year of the story on many levels, hence make sure the relationship dramatic narrative of the dialogue mechanism in the work of narrative fiction, where he remains a dramatic payload always, even dabble in any field of well-known narrative fields, and in view of the importance of dialogue in the narrative being achieves several functions, including imaging and personal development events and providing air or case research sought to clarify the role of dialogue in the story taking the writer Jamal Nuri stories a model embodies it, the search at the entrance and two sections to ensure entrance define the concept of dialogue and functions in the fiction work, he singled out the first section of the study (external dialogue) in terms of the composite dialogue, and dialogue Altrmisi, dialogue abstract while singled section II study (internal dialogue) in terms of the monologue, and communing technical and flashbacks And the research found that the narrator of the friendly variety in his conversations anecdotal, as he tends to the internal dialogues most likely end may be ones for a reader and deepen in the folds of his texts of short stories in order to reach the writer thinking and his goal of them, and speak into the story like one of the characters live events this shows the extent of interaction and compatibility with his characters.
Recruitment in the Legal Information Industry: a Perspective from CB Resourcing
Authors: Burton Simon 
Published: August 2022

AbstractIn recent years, the company called CB Resourcing has established itself in the recruitment business and regularly advertises for positions in the knowledge management, business research, legal tech and law librarianship worlds. In this short article one of the Directors of CB Resourcing, Simon Burton, offers some thoughts about the recruitment business, the current state of the market and describes the services that are provided by the company. The article has been written in the form of an interview with questions posed by the editor of this journal and answers given by Simon Burton.
Machine Learning Based Indian raga Identification for Music Therapy
Authors: KIRAN  , S Sunil Kumar D 
Published: August 2022

Abstract
The world has music. The inherent nature of music's language has a wide range of psychological effects on people. Numerous academics have looked into how music affects the mind. Medical science and technological developments are rediscovering music's therapeutic benefits. A Raga in Indian classical music is used to represent emotions. Additionally, a particular Raga might amplify a particular emotion. In the history of Indian art and medicine, music therapy has a significant role. In recent years, Indian music therapy has grown significantly in significance, and music therapy clinics there are drawing interest from all over the world. Using Musicure, a smartphone app for Indian music therapy, this paper gives a practical method to music therapy.
PELAKSANAAN PENDAFTARAN TANAH PERTAMA KALI TERHADAP TANAH MILIK ADAT YANG BELUM BERSERTIPIKAT DI KANTOR PERTANAHAN KOTA PADANG PANJANG
Authors: Syuryani Syuryani , Hidayat Rian 
Published: August 2022

Sistem pendaftaran tanah untuk pertama kali di Indonesia dilaksanakan melalui pendaftaran tanah secara sistematik dan sporadik, pendaftaran tanah secara sistematik didasarkan pada suatu rencana kerja dan dilaksanakan di wilayah-wilayah yang ditetapkan oleh Menteri Agraria, sedangkan pendaftaran tanah secara sporadik dilaksanakan atas permintaan pihak yang berkepentingan dengan menunjukkan bukti kepemilikan terhadap suatu bidang tanah, dengan adanya ketentuan tersebut terhadap tanah milik adat yang tidak memiliki bukti kepemilikan secara formal membuat kegiatan pendaftaran tanah untuk pertama kali menjadi sedikit terhambat. Tanah milik adat di Sumatera Barat khususnya Kota Padang Panjang merupakan sebuah kearifan lokal yang masih bertahan, yaitu status kepemilikan tanah tidak diturunkan kepada pribadi, tetapi kepada banyak pihak yang memiliki ikatan keluarga (kaum), apapun yang akan dilakukan terhadap tanah itu harus mendapatkan izin dari kaum. Permasalahan yang dibahas dalam penelitian ini adalah tentang bagaimana pelaksanaan pendaftaran tanah pertama kali terhadap tanah milik adat yang belum bersertipikat di Kantor Pertanahan Kota Padang Panjang dan apa saja kendala-kendala yang dihadapi dalam pelaksanaan pendaftaran tanah pertama kali terhadap tanah milik adat yang belum bersertipikat di Kantor Pertanahan Kota Padang Panjang. Dalam penelitian ini diperoleh hasil bahwa untuk pelaksaan pendaftaran tanah pertama kali terhadap tanah milik adat yang belum bersertipikat di Kota Padang Panjang mengacu pada Peraturan Pemerintah Nomor 24 Tahun 1997 yang disempurnakan dengan Peraturan Pemerintah Nomor 18 Tahun 2021 dan untuk persyaratannya mengacu pada Surat Edaran Kepala Kantor Wilayah Badan Pertanahan Nasional Nomor 500/88/BPN-2007. Kendala - kendala yang ditemukan dalam penelitian terdiri atas kendala dari faktor internal dan kendala dari faktor eksternal. Kata Kunci: Pelaksanaan Pendaftaran Tanah, Pertama Kali, Tanah Milik Adat
ANALISIS PENERIMAAN PAJAK KENDARAAN BERMOTOR (PKB) DARI LAYANAN DRIVE THRU TERHADAP PENDAPATAN ASLI DAERAH (PAD) KOTA PADANG
Authors: Sartika Dewi , Febriyeni Elsa , Ilyas Andre 
Published: August 2022

Jumlah wajib pajak di sebuah kota sangat banyak, sehingga harus mengantri dan membutuhkan waktu lama dalam membayar Pajak Kendaraan Bermotor (PKB) tahunan jika dilakukan secara konvensional. Oleh karena itu, kantor SAMSAT Kota Padang membuat inovasi layanan SAMSAT Drive Thru untuk memaksimalkan pelayanan terhadap wajib pajak.Tujuan penelitian ini adalah untuk mendeskripsikan kontribusi penerimaan Pajak Kendaraan Bermotor (PKB) dari layanan Drive Thru terhadap Pendapatan Asli Daerah (PAD) di Kota Padang. Penelitian ini menggunakan pendekatan deskriptif kualitatif yang bertujuan untuk menggambarkan tentang focus penelitian yang meliputi penerimaan Pajak Kendaraan Bermotor (PKB) dari layanan Drive Thru, kontribusi penerimaan Pajak Kendaraan Bermotor (PKB) terhadap Pendapatan Asli Daerah (PAD), serta kendala yang dihadapi SAMSAT Kota Padang dengan adanya sistem layanan Drive Thru. Hasil penelitian ini menunjukkan bahwa penerimaan Pajak Kendaraan Bermotor (PKB) dari layanan Drive Thru mampu dalam meningkatkan penerimaan Pajak Kendaraan Bermotor (PKB). Penelitian ini juga menunjukkan bahwa Penerimaan Pajak Kendaraan Bermotor (PKB) juga mampu meningkatkan Pendapatan Asli Daerah di Kota Padang .
Kata Kunci: Penerimaan PKB, Layanan Drive Thru, PAD
EFEKTIFITAS KONSELING PREHOSPITAL CARE MANAJEMAN PADA MASALAH GAWAT DARURAT PADA MASYARAKAT DI WILAYAH KERJA PUSKESMAS KURANJI TAHUN 2021
Authors: Setiarini Sari , Gusti Dalina , Suherlin Nicen 
Published: August 2022

Indonesia menjadi negara ketiga di Asia di bawah Tiongkok dan India dengan 38.297 total kematian akibat kecelakaan lalu lintas di tahun 2015 ( Nasional.Republika. 2 Mei 2017). Data WHO (2013) menyebutkan dalam dua tahun terakhir kecelakaan lalu lintas di Indonesia menjadi pembunuh ke tiga setelah penyakit jantung koroner dan tuberculosis. Jumlah korban meninggal dunia akibat kecelakaan lalu lintas selama 2017 tercatat 538 jiwa (60%). Prehospital care sebagai bentuk pelayanan Emergency Medical Service (EMS). Karena peranan prehospital care sebagai bagian dari EMS ini sangat penting dalam mengurangi angka morbiditas dan mortalitas korban kecelakaan lalu lintas. Tujuan dari penelitian ini adalah untuk mengetahui efektifitas konseling prehospital care manajement kegawat daruratan di wilayah kerja Puskesmas Kuranji Tahun 2021.
Penelitian yang dilakukan Penelitian ini menggunakan rancangan Quasy Experiment dengan pendekatan Two Group Pretes and Posttes design. Penelitian ini dilakukan kepada masyarakat yang tinggal di di wilayah kerja Puskesmas Kuranji Tahun 2021 dengan jumlah 20 responden. Analisis data dalam penelitian ini menggunakan uji non parametric (uji Wilcoxon)
Hasil penelitian ini menunjukkan bahwa ada pengaruh konseling terhadap peningkatan pengetahuan responden sebelum dan sesudah di lakukan konseling tentang pre-hospital care manajemen di wilayah kerja Puskesmas Kuranji. Dari hasil uji Wilcoxon didapatkan bahwa mean rank pengetahuan respon tentang prehospital care manajemen sebelum dan sesudah di lakukan konseling yaitu 5.00. Berdasarkan hasil uji statistic di dapatkan nilai P value=0,020 (P < 0,05 )

Kata kunci : Konseling, Prehospital care manajemen, kegawatdaruratan
ANALISIS KEAKURATAN MOVING AVERAGE CONVERGENCE DIVERGENCE DAN STOCHOSTIC OSCILLATOR PADA PERUSAHAAN SUB SEKTOR PERBANKAN YANG TERDAFTAR DI BURSA EFEK INDONESIA (BEI)
Authors: Reswita Yefri , Nanda Nanda , Rahmadani Yola 
Published: August 2022

Penelitian ini bertujuan untuk menganalisis keakuratan metode Moving Average Convergence Divergence (MACD) dan Stochostic Oscillator (S0) dalam menentukan sinyal membeli dan menjual. Sinyal membeli dan menjual didapatkan dari perpotongan garis MACD dan Stochostic Oscillator dengan format standar. Konsep pada penelitian ini adalah : 1) membandingkan rata-rata return antara MACD dan BHAR per sub periode. 2) membandingkan rata-rata return antara SO dan BHAR. 3) membandingkan kinerja antara MACD dan BHAR mana yang lebih akurat. Penelitian ini menggunakan sampel yaitu perusahaan perbankan yang terdaftar di Bursa Efek Indonesia (BEI) periode 2016-2021. Teknik pengumpulan sampel ini menggunakan purposive Sampling, berdasarkan kriteria-kriteria yang telah ditentukan, diperoleh 5 perusahaan yang dapat dijadikan sampel. Teknik analisis data menggunakan analisis deskriptif, normalitas, Independent sample Test dan Mann-Whitney U. Hasil penelitian menunjukkan disaat pasar sedang stabil sebaiknya kita berinvestasi atau BHAR, sebaliknya jika disaat pasar sedang krisis sebaiknya menggunakan analisis teknikal MACD
Kata Kunci : Analisis Teknikal, Moving Average Convergence Divergence, Stochostic Oscillator, Buy And Hold Strategy, Sinyal membeli dan menjual.