bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Harga dan Lokasi Terhadap Keputusan Pembelian (Studi pada Konsumen Toko Roti Modern Bakery Cukir Jombang)
Authors: Hakim Lukman 
Published: June 2022

This study aims to determine the effect of Price and Location on Consumer Purchase Decisions at Cukir Jombang Bakery Modern. This study uses quantitative data analysis techniques. This study uses primary data collection techniques obtained from questionnaires. The sample in this study were 30 respondents. Samples were taken using non-probability sampling techniques in the form of incidental sampling, namely the technique of determining samples based on chance, that is, anyone who accidentally met with a researcher could be used as a sample, if viewed by the person who was met by chance it was suitable as a source of data. The data analysis technique uses Multiple Linear Regression. The results showed that: (1) Prices partially have a positive and significant influence on purchasing decisions (2) The location partially has a positive and significant influence on purchasing decisions (3) Prices and locations simultaneously have a positive and significant influence on purchasing decisions in Bakery Modern Cukir Jombang.
Pengaruh Citra Merek dan Harga Terhadap Keputusan Pembelian Pasta Gigi Close Up di Pondok Pesantren Darul Falah V
Authors: Aslamiyah Robiatul 
Published: June 2022

The purpose of this research is to analyze the influence of the brand image and the price toward the decision to buy the toothpaste product of Closeup in Islamic boarding school of Darul falah V, Cukir Diwek Jombang by using research technique of quantitative and method of causal research method. The data was got from the survey and questionnairs distributed to 40 students of islamic boarding school of Darul Falah V, Cukir Diwek Jombang. The purposive sampling was used to take the sample consisting of 40 students by thge specific critrerias related to the research purpose in order to answer the research problem. The technique of data anaysis used multiple linear regression. The hyphothesis testing showed the results that: (1) The brand image partially and significantly influences the decision to buy the toothpaste of Closeup in Islamic boarding school of Darul Falah V, Cukir Diwek Jombang. (2) The price does not partially and significantly influences the decision the decision to buy the toothpaste of Closeup in Islamic boarding school of Darul Falah V, Cukir Diwek Jombang and (3) The brand image and the price simultaneously influence the decision to buy the toothpaste of Closeup in Islamic boarding school of Darul Falah V, Cukir Diwek Jombang.
Pengaruh Pelatihan Kerja dan Disiplin Kerja Terhadap Produktivitas Kerja Karyawan di PT Maan Ghodaqo Shiddiq Lestari (MAAQO) Jombang
Authors: Fadilah Nur 
Published: June 2022

This study aims to determine wheater or not the influence of job training and work discipline on the work productivity of employees at PT MAAQO. The type of research used in this study is quantitative research with an associative approach. The sampling technique used was saturated samples with a sample of 76 employees at PT MAAQO. This sudy uses the technique of collecting data on obsevations, interviews, questionnaires and documentation. Data analysis techniques used are multiple linear regression analysis, t test and f test with results that show that: (1) Job training and work discipline simultaneously affect work productivity at PT MAAQO. (2) Work discipline partially has a positive and significant effect on work productivity at PT MAAQO. (3) Job training and work discipline simultaneously affect work productivity at PT MAAQO.
Pengaruh Komunikasi dan Penilaian Kinerja Terhadap Kepuasan Kerja Pengurus Pondok Pesantren Putra Tebuireng Jombang
Authors: Mucholifah Mucholifah 
Published: June 2022

This study aims to determine the effect of communication and performance appraisal on the job satisfaction of administrators at the Male of boarding school tebuireng jombang. The method used in this study is a quantitative research method and uses a causal or causal approach. The results showed that: (1) Communication did not influence partially on the job satisfaction of male boarding school tebuireng jombang administrators, (2) Performance evaluation partially influenced job satisfaction of male boarding school tebuireng jombang administrators, (3) Communication and performance appraisal influenced Simultaneous to the job satisfaction of the male boarding school boarder in Jombang.
Pengaruh Budaya Organisasi Dan Gaya Kepemimpinan Terhadap Komitmen Organisasi Pengurus Pondok Pesantren Roudlotul Qur’an Darul Falah III Cukir Jombang
Authors: Nasarudin Lalu , Frianto Agus 
Published: June 2022

Penelitiannini bertujuan untuk mengetahui pengaruh Budaya Organisasi Dan Gaya Kepemipinan Terhadap Komitmen Pengurus pada Pondok Pesantren Roudlotul Qur’an Darul Falah III cukir Jombang. Metodel atau metode yang dipakaidalam penelitian ini yaitu metode penelitian kuantitatif dan memakai pendekatan kausal atau sebab akibat. Populasi pada penelitian ini merupakan pengurus yang mengabdi pada Pondok Pesantren Roudlotul Qur’an Darul Falah III Cukir Jombang. Teknik pengambilan sampel menggunkan sampel jenuh dengan jumlah sampel sebanyak 50 pengurus. Pengolahan data dilakukan dengan menggunakan program SPSS v23. Hasil dari analisa data menunjukkan bahwa budaya organisasi dan gaya kepemimpinan secara bersama-sama (simultan) berpengaruh terhadap komitmen organisasi..
Kata kunci: Budaya organisasi; Gaya kepemimpinan; Komitmen organiasi
Pengaruh Keselamatan dan Kesehatan Kerja (K3) dan Lingkungan Kerja Terhadap Produktivitas Kerja Karyawan CV Surya Kencana Food
Authors: Apriliyani Rizka 
Published: June 2022

This study aims to analyze the influence of occupational safety and health (K3) and work environment on the work productivity of employees CV Surya Kencana Food. This research is quantitative research using causal or causal approach. Data collection using research instruments, data analysis is statistical, with the intention to describe and test hypotheses. The population in this study was a permanent employee of CV Surya Kencana Food. The sample was determined by saturated sampling and obtained 57 respondents as samples. The results showed that: (1) occupational safety and health (K3) has no partial and significant effect on employee work productivity (2) the work environment has a partial and significant effect on employee work productivity (3) occupational safety and health (K3) and the work environment simultaneously affects employee work productivity.
Keywords : Occupational Safety and Health (K3);Work Environment; Employee Work Productivity
Pengaruh Human Relation dan Lingkungan Kerja Terhadap Kinerja Karyawan PT. Queen Ice Asia Bangkalan
Authors: Lutfiya Ika Inayatul , Anah Lik 
Published: June 2022

This research was conducted to find out partially and simultaneously the influence of human relations and work environment on performance at PT. Queen Ice Asia Bangkalan. This study uses quantitative methods, with data collection techniques through observation, interviews, and distributing questionnaires. The population is all employees of PT. Queen Ice Asia Bangkalan. The sample used was 35 people. The data analysis technique used is multiple linear regression. The results showed that: (1) Human relations partially positive and significant effect on the performance of employees of PT. Queen Ice Asia Bangkalan, (2) The work environment partially has a positive and insignificant effect on the performance of PT. Queen Ice Asia Bangkalan, (3) Human relations and work environment simultaneously affect the performance of employees of PT. Asian Ice Queen Bangkalan.
Keyword: Human Relatio; Work environment; Employee Performance
Analisis Sistem Informasi Akuntansi Penjualan dalam Upaya Meningkatkan Efektivitas Pengendalian Intern (Studi Pada Perum BULOG Sub Divre Kediri)
Authors: Fitriyah Nurlailatul , Ari Pertiwi Dwi 
Published: June 2022

This research aims to acknowladge how the application of accounting information system sales and the implementation of accounting information system sales in effort to improve internal control effektiveness at Perum Bulog Sub Divre Kediri. The research is a case study. The analyzed method were using the methods of analysis deskriptif. The result of this reasearch ishow that the application of accounting information system sales and the implementation of accounting information system sales in effort to improve internal control effektiveness at Perum Bulog Sub Divre Kediri most have been applicated and implemented in accordance with the theory formulate, then it can be concluded that the application of accounting information system sales and the implementation of accounting information system sales in effort to improve internal control effektiveness at Perum Bulog Sub Divre Kediri is running well.
Analisis Penerapan Akuntansi Murabahah Berdasarkan PSAK 102 (Studi Kasus BMT Maslahah Cabang Pembantu Diwek)
Authors: Ernawati Luluk 
Published: June 2022

The purpose of this research is to know appropriateness of a murabahah accounting related to the recognition, measurement, performance and disclosure at BMT Maslahah Capem Diwek in order to improve professionalism and public trust that the implementation of a Murabahah transaction already fit with the accounting standards.
This research uses qualitative descriptive method by describing and comparing data obtained by researchers directly regarding the recognition, measurement, performance and disclosure of Murabahah transactions. Research Data obtained by researchers through observations, interviews and documentation with the head of office, accounts of financing officers and the teller section of the BMT Maslahah Capem Diwek.
The results of this research show that the practice of Murabahah accounting in transaction financing related to the recognition, measurement, performance and disclosure of transactions accounting Murabahah at BMT Maslahah Capem Diwek is not in accordance with PSAK 102.
Faktor-Faktor yang Berpengaruh pada Kualitas Laba (Studi pada Sektor Perdagangan Besar/Grosir dan Kecil/Eceran dalam Bursa Efek Indonesia 2016-2018)
Authors: Heni Nurlailia  , Ervina Deasy 
Published: June 2022

Earnings quality provides an explanation related to the company's financial achievement, which in turn can be used as a basis for consideration by users of financial statements. A profit has a quality meaning if the company is able to use its operating cash inflows to finance the company's operating activities. This research is intended to examine the influence of earning quality factors.
The type of research used is quantitative research. This study was conducted on the IDX by selecting the population in the large / wholesale and small / retail trade sector for the period 2016-2018. The sample obtained is 72. The required hypothesis testing is multiple linear regression. The research found that (1) profitability has no affect on earning quality, (2) liquidity affects on earnings quality, (3) levareage has no affects on earning quality, and (4) also firmsize has no affects on earning quality.
Pemahaman Laporan Keuangan Berbasis SAK EMKM terhadap Kualitas Laporam Keuangan pada CV Karya Perdana Bapang Jombang
Authors: Hanifah Fitrotul , Agustina Rachma 
Published: June 2022

Standart Akuntansi Keuangan Entitas Mikro Kecil dan Menengah merupakan salah satu standar Keuangan yang ditetapkan untuk mempermudah UMKM menyusun dan menyajikan laporan keuangan yang lebih sederhana dan mudah dipahami bagi investor dan kreditor untuk memberikan bantuan pembiayaan bagi para pengusaha UMKM. Tujuan penelitian ini untuk mengetahui apakah pemahaman pelaku umkm berpengaruh terhadap pencatatan laporan keuangan perusahaan dan untuk mengetahui apakah pemilik perusahaan sudah menerapkan laporan keuangan yang sesuai dengan standart akuntansi untuk UMKM. Jenis penelitian ini adalah penelitian kualitatif dengan mendeskripsikan laporan keuangan perusahaan. Sumber data yang digunakan dalam bentuk primer dan sekunder yang dikumpulkan dengan teknik seperti wawancara, observasi, dokumentasi, dan kepustakaan. Teknik analisis yang digunakan reduksi data, penyajian data dan simpulan. Hasil penelitian menunjukkan bahwa CV Karya perdana belum sepenuhnya menerapkan laporan keuangan yang sesuai dengan SAK EMKM karena keterbatasan pengetahuan pemilik dan tidak adanya sosialisasi dari pihak terkait.
Kata kunci : Laporan Keuangan, SAK EMKM, UMKM
Analisis Harga Pokok Produksi Sebelum dan Sesudah Menggunakan Pendekatan Full Costing sebagai Penentu Harga Jual pada Pabrik Tahu CV Karya Perdana
Authors: Nur Aini Novia , Agustina Rachma 
Published: June 2022

Tujuan penelitian ini adalah untuk membantu perusahaan bisa menjual produksinya dengan harga jual yang optimal dan bisa bersaing kompetitif dengan perusahaannya yang sejenis. Jenis penelitian ini adalah penelitian kualitatif dengan mendeskripsikan laporan keuangan harga pokok produksi. Sumber data yang digunakan dalam bentuk primer dan sekunder yang dikumpulkan dengan teknik seperti wawancara, observasi, dokumentasi, dan kepustakaan. Teknik yang dilakukan dianalisis menggunakan reduksi data, display data dan simpulan. Hasil penelitian menunjukkan bahwa CV Karya perdana masih menggunakan metode menghitung harga pokok produksi secara sederhana dan tidak memasukkan biaya secara rinci yaitu tidak mengkalkulasikan semua biaya overhead pabrik. Dalam penelitian ini juga menunjukkan perbandingan harga pokok dan harga jual sehingga terdapat selisih diantaranya.
Kata Kunci: Harga Pokok Produksi, Full Costing, Harga Jual
Pengaruh CAR, NPL, dan LDR terhadap Profitabilitas (Studi Empiris pada Perbankan yang Terdaftar di Bursa Efek Indonesia Selama Periode 2016-2018)
Authors: Humairoh Syirin , Agustina Rachma 
Published: June 2022

Profitability is the ratio which links the profit from sales and investment. From the profitability ratio,the stakeholder and shareholder can see and understand the level of company profitability. This study has purpose to determine the effect of Capital Adequacy Ratio / CAR, Loan To Deposit Ratio / LDR, Non Performing Loans / NPL towards banking companies listed on the Indonesian stock exchange with time period of 2016-2018. In this research, researchers used sampling method which is a purposive sampling method. Samples that meet the criteria in this study are 16 banks for the time period of 2016-2018. The type of research used in this study is quantitative research. The results of this study indicate that the Capital Adequacy Ratio / CAR has a significant effect on profitability, Non Performing Loans / NPL do not have a significant effect on profitability, while the Loan To Deposit Ratio / LDR has no significant effect on profitability.
Keywords: CAR; NPL; LDR; Profitability
Adoptive NK Cell Transfer as a Treatment in Colorectal Cancer Patients: Analyses of Tumour Cell Determinants Correlating With Efficacy In Vitro and In Vivo
Authors: Lanuza Pilar M. , Alonso M. Henar , Hidalgo Sandra , Uranga-Murillo Iratxe , García-Mulero Sandra , Arnau Raquel , Santos Cristina , Sanjuan Xavier , Santiago Llipsy , Comas Laura , Redrado Sergio , Pazo-Cid Roberto , Agustin-Ferrández M. Jose , Jaime-Sánchez Paula , Pesini Cecilia , Gálvez Eva M. , Ramírez-Labrada Ariel , Arias Maykel , Sanz-Pamplona Rebeca , Pardo Julián 
Published: June 2022

BackgroundColorectal cancer (CRC) is a heterogeneous disease with variable mutational profile and tumour microenvironment composition that influence tumour progression and response to treatment. While chemoresistant and poorly immunogenic CRC remains a challenge, the development of new strategies guided by biomarkers could help stratify and treat patients. Allogeneic NK cell transfer emerges as an alternative against chemoresistant and poorly immunogenic CRC.MethodsNK cell-related immunological markers were analysed by transcriptomics and immunohistochemistry in human CRC samples and correlated with tumour progression and overall survival. The anti-tumour ability of expanded allogeneic NK cells using a protocol combining cytokines and feeder cells was analysed in vitro and in vivo and correlated with CRC mutational status and the expression of ligands for immune checkpoint (IC) receptors regulating NK cell activity.ResultsHLA-I downmodulation and NK cell infiltration correlated with better overall survival in patients with a low-stage (II) microsatellite instability-high (MSI-H) CRC, suggesting a role of HLA-I as a prognosis biomarker and a potential benefit of NK cell immunotherapy. Activated allogeneic NK cells were able to eliminate CRC cultures without PD-1 and TIM-3 restriction but were affected by HLA-I expression. In vivo experiments confirmed the efficacy of the therapy against both HLA+ and HLA− CRC cell lines. Concomitant administration of pembrolizumab failed to improve tumour control.ConclusionsOur results reveal an immunological profile of CRC tumours in which immunogenicity (MSI-H) and immune evasion mechanisms (HLA downmodulation) favour NK cell immunosurveillance at early disease stages. Accordingly, we have shown that allogeneic NK cell therapy can target tumours expressing mutations conferring poor prognosis regardless of the expression of T cell-related inhibitory IC ligands. Overall, this study provides a rationale for a new potential basis for CRC stratification and NK cell-based therapy.
Emerging Role of MicroRNAs in the Therapeutic Response in Cervical Cancer: A Systematic Review
Authors: Ravegnini Gloria , Gorini Francesca , Dondi Giulia , Tesei Marco , De Crescenzo Eugenia , Morganti Alessio G. , Hrelia Patrizia , De Iaco Pierandrea , Angelini Sabrina , Perrone Anna Myriam 
Published: June 2022

Cervical cancer is a common female cancer, with nearly 600,000 cases and more than 300,000 deaths worldwide every year. From a clinical point of view, surgery plays a key role in early cancer management, whereas advanced stages are treated with chemotherapy and/or radiation as adjuvant therapies. Nevertheless, predicting the degree of cancer response to chemotherapy or radiation therapy at diagnosis in order to personalize the clinical approach represents the biggest challenge in locally advanced cancers. The feasibility of such predictive models has been repeatedly assessed using histopathological factors, imaging and nuclear methods, tissue and fluid scans, however with poor results. In this context, the identification of novel potential biomarkers remains an unmet clinical need, and microRNAs (miRNAs) represent an interesting opportunity. With this in mind, the aim of this systematic review was to map the current literature on tumor and circulating miRNAs identified as significantly associated with the therapeutic response in cervical cancer; finally, a perspective point of view sheds light on the challenges ahead in this tumor.Systematic Review RegistrationPROSPERO (CRD42021277980).
Efficacy of Osimertinib in EGFR-Mutated Advanced Non-small-Cell Lung Cancer With Different T790M Status Following Resistance to Prior EGFR-TKIs: A Systematic Review and Meta-analysis
Authors: Yi Xiao-Fang , Song Jun , Gao Ruo-Lin , Sun Li , Wu Zhi-Xuan , Zhang Shu-Ling , Huang Le-Tian , Ma Jie-Tao , Han Cheng-Bo 
Published: June 2022

PurposeEpidermal growth factor receptor (EGFR) T790M-negative/unknown advanced non-small cell lung cancer (NSCLC) patients lack subsequent approved targeted therapies. This meta-analysis aimed to assess the efficacy of osimertinib in advanced NSCLC patients with different T790M status after resistance to prior first- or second-generation EGFR-tyrosine kinase inhibitors (EGFR-TKIs) and to predict the subgroups that may benefit beside T790M-positive disease.MethodsPubMed, Embase, Web of Science, and Cochrane Library databases were searched for relevant trials. Meeting abstracts were also reviewed to identify appropriate studies. Studies evaluating the efficacy and/or survival outcomes of osimertinib in patients with different T790M status (positive, negative, or unknown) after resistance to prior first- or second-generation EGFR-TKIs were enrolled, and data were pooled to assess hazard ratios (HRs) or relative risk ratios (RRs) in terms of overall survival (OS), progression-free survival (PFS), and objective response rate (ORR).ResultsA total of 1,313 EGFR-mutated NSCLC patients from 10 retrospective and one prospective studies treated with osimertinib after resistance to first- or second-generation EGFR-TKIs were included. In overall groups, T790M-positive patients showed an improved OS (HR=0.574, p=0.015), PFS (HR = 0.476, p = 0.017), and ORR (RR = 2.025, p = 0.000) compared with T790M-negative patients. In the brain metastases subgroup, no significant difference in OS was observed between T790M-positive and T790M-negative patients (HR = 0.75, p = 0.449) or between T790M-positive and T790M-unknown patients (HR = 0.90, p = 0.673). In the plasma genotyping subgroup, PFS was similar between T790M-positive and T790M-negative patients (HR = 1.033, p = 0.959).ConclusionPatients with progressive brain metastases on first- or second-generation EGFR-TKIs can benefit from subsequent osimertinib therapy regardless of T790M status. Patients with plasma T790M-negative status and lack of tissue genotyping should be allowed to receive osimertinib treatment.