bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metamorphic Evolution and Orogenic Process Related to the Eastern Paleo-Tethyan Warm Subduction and Indochina–South China Collision
Authors: Wang Huining , Liu Fulai , Wang Fang , Ji Lei , Zhu Jianjiang , Thanh Ngo Xuan 
Published: November 2022

Abstract
The eastern Paleo-Tethyan Jinshajiang–Ailaoshan–Song Ma orogenic belt in the Southeast Tibetan Plateau represents the tectonic boundary between the Indochina and South China blocks. Regional Cenozoic lithospheric strike-slip movements caused by the India–Asia collision have modified many of the pristine geological records associated with the Indosinian orogeny. The lack of reliable petrological evidences, particularly of high-pressure (HP) metamorphism, has hindered the tracing of the evolutionary history of the Paleo-Tethyan orogenic belt. We report the mineralogy, geochemistry, geochronology and thermodynamic modelling of eclogite lenses/blocks and their host garnet–phengite schists from the Song Ma Suture Zone of Northwest Vietnam and reveal their protolith origins and metamorphic evolution. The eclogites are geochemically similar to mid-ocean ridge basalt, showing weak depletions in high field-strength elements, positive to slightly negative whole-rock ɛNd(t) ratios (−1.69 to +5.15) and slightly high 87Sr/86Sr(t) ratios (0.70466–0.70834). The igneous protolith of the eclogites formed in the late Silurian (425.4 ± 3.6 Ma; igneous zircon dating, 638–459 Ma TDM dating), which makes them the oldest known mid-ocean ridge mafic rocks in an ancient Paleo-Tethyan Ocean. Various eclogites preserve similar peak mineral assemblages (garnet + omphacite + phengite + rutile + quartz ± epidote/clinozoisite ± kyanite ± winchite) under indistinguishable peak conditions. Their prograde P–T trajectories show a uniform pattern of progressive heating and weak compression along a geothermal gradient of 8°C–10°C/km, indicating a warm subduction setting at a low angle that contrasts with the cold oceanic subduction recorded in the adjacent Paleo-Tethyan suture zones. Combined with detrital U–Pb ages from previous studies, our geochronological data indicate that the host schists originated from continental crust within the South China Block and underwent a pervasive Triassic HP metamorphism related to the Indosinian orogeny. The eclogites and host schists yielded HP metamorphic ages of 239–234 Ma and retrogressive amphibolite-facies metamorphic ages of 231–229 Ma, suggesting rapid cooling (14.0°C–21.6°C/Myr) and exhumation (6.4 km/Myr) from the mantle to the crust. The Song Ma eclogites and their host schists formed when the final ocean closure transitioned to the initial Indochina–South China collision. The Song Ma eclogites and their host schists provide essential information on the opening and closure of the eastern Paleo-Tethys and the subsequent amalgamation of Southeast Asian continental fragments.
Gene-by-environment interactions in plants: Molecular mechanisms, environmental drivers, and adaptive plasticity
Authors: Napier Joseph D , Heckman Robert W , Juenger Thomas E 
Published: November 2022

Abstract
Plants demonstrate a broad range of responses to environmental shifts. One of the most remarkable responses is plasticity, which is the ability of a single plant genotype to produce different phenotypes in response to environmental stimuli. As with all traits, the ability of plasticity to evolve depends on the presence of underlying genetic diversity within a population. A common approach for evaluating the role of genetic variation in driving differences in plasticity has been to study genotype-by-environment interactions (G × E). G × E occurs when genotypes produce different phenotypic trait values in response to different environments. In this review, we highlight progress and promising methods for identifying the key environmental and genetic drivers of G × E. Specifically, methodological advances in using algorithmic and multivariate approaches to understand key environmental drivers combined with new genomic innovations can greatly increase our understanding about molecular responses to environmental stimuli. These developing approaches can be applied to proliferating common garden networks that capture broad natural environmental gradients to unravel the underlying mechanisms of G × E. An increased understanding of G × E can be used to enhance the resilience and productivity of agronomic systems.
Is Truth Primitive?
Authors: Wyatt Jeremy 
Published: November 2022

Abstract
Primitivist theories of truth have been defended by some of the luminaries of analytic philosophy, including the early Moore and Russell, Frege, Davidson, and Sosa. In this paper, I take up a contemporary primitivist theory that has been systematically developed throughout a sizeable body of work but has yet to receive sustained critical attention—Jamin Asay's primitivist deflationism. Asay's major ambitions are to defend a novel primitivist account of the concept truth and to harmonise that account with a deflationary theory of the property truth. I will elaborate a thoroughgoing critique of primitivist deflationism, arguing that we have reason to doubt all of the five theses that constitute the view. Along the way, I will also highlight a number of possible escape routes for the primitivist deflationist, explaining how they can make the view more resilient even as they compel us to rework some of its central commitments.
Effects of Exercise Programs on Functional Capacity and Quality of Life in People With Acquired Brain Injury: A Systematic Review and Meta-Analysis
Authors: Pérez-Rodríguez Marta , Gutiérrez-Suárez Andrea , Arias Jacobo Ángel Rubio , Andreu-Caravaca Luis , Pérez-Tejero Javier 
Published: November 2022

Abstract

Objective
The aims of this systematic review and meta-analyses were to evaluate the effects of exercise on the functional capacity and quality of life (QoL) of people with acquired brain injury (ABI) and to analyze the influence of training variables.

Methods
Five electronic databases (MEDLINE, Cochrane Library, CINAHL, SportDiscus, and Web of Science) were searched until October 2021 for clinical trials or experimental studies examining the effects of exercise on the functional capacity and QoL in adults with ABI and comparing exercise interventions with non-exercise (usual care).

Results
Thirty-eight studies were evaluated. A total sample of 2219 people with ABI (exercise, n = 1572; control, n = 647) were included in the quantitative analysis. A greater improvement was observed in walking endurance (z score = 2.84), gait speed (z score = 2.01), QoL physical subscale (z score = 3.42), and QoL mental subscale (z score = 3.00) was observed in the experimental group than in the control group. In addition, an improvement was also observed in the experimental group in the “Timed Up and Go” Test scores and balance without differences from the control group. Significant interactions were also observed between the rehabilitation phases, type, frequency and volume of training, and overall effects.

Conclusion
The results suggest that exercise improves functional capacity and QoL regardless of model training, highlighting the effectiveness of long-term exercise that includes short sessions with components such as strength, balance, and aerobic exercise.

Impact
The results shown in this systematic review with meta-analysis will allow physical therapists to better understand the effects of training on people with ABI.
Firm Listing Status, Firm Size, and the Financing of Investment
Authors: Lé Mathias , Vinas Frédéric 
Published: November 2022

Abstract
How do companies finance their investments? We examine the financing of investments according to firms’ listing status, their size, and the nature of the investments. We show that private firms rely more on bank credit than public firms and less on financial debt, equity, and cash flow. We also show that the contribution of financial debt and equity increases with firm size. Considering both dimensions, we always find an increasing contribution of other financial debt and equity with firm size in both populations. Therefore, even in a bank-based economy, equity plays an important role in the investment of larger private firms. (JEL D25, E22, G21, G30, G31, G32)
The discovery of new Chilean taxa revolutionizes the systematics of Geoplaninae Neotropical land planarians (Platyhelminthes: Tricladida)
Authors: Almeida Ana Laura , Álvarez-Presas Marta , Carbayo Fernando 
Published: November 2022

AbstractTwo subfamilies of land planarians (Geoplanidae) are endemic to the Neotropical region, namely Geoplaninae (with 29 genera and 346 nominal species, most of which are from Brazil) and its sister-group Timyminae, with only two Chilean species. The systematics of these groups through morphology and molecular data (COI and 28S rDNA genes), including nine new Chilean species, is re-assessed in this study. The great morphological diversity of the Chilean species is congruent with the molecular trees and, accordingly, five new genera (Adinoplana, Harana, Myoplana, Sarcoplana and Transandiplana) are proposed, each characterized by putative synapomorphies. Seven new tribes are also erected (Adinoplanini, Gusanini, Haranini, Inakayaliini, Myoplanini, Polycladini and Sarcoplanini), each one monogeneric, except Geoplanini (which includes all genera under the current concept of Geoplaninae plus the Chilean Transandiplana) and Sarcoplanini (with Sarcoplana and the already known Mapuplana, Pichidamas and Wallamapuplana). Re-diagnoses of Geoplaninae, Timymini, Gusana, Inakayalia, Polycladus and Pichidamas are proposed and biogeographic remarks on Transandiplana are provided
Implementation of a Naloxone Best Practice Advisory Into an Electronic Health Record
Authors: Srikumar Jainaha K. , Daniel Kristin , Balasanova Alёna A. 
Published: November 2022

Objectives
Naloxone is a harm reduction tool for mitigating the rising rate of opioid overdose deaths. We sought to develop and implement an alert in the electronic health record outlining which patients are at higher risk of opioid overdose and should be coprescribed naloxone. Our aim was to increase coprescribing of naloxone to qualified patients. We also endeavored to evaluate naloxone prescription volume, fill rates, and statewide dispenses before and after alert implementation.

Methods
We developed the electronic alert according to a state opioid safety initiative specifying under which conditions it should activate. We collected data on naloxone prescriptions ordered in the 5 months before and after alert implementation and unique patients with a naloxone dispense statewide. We used internal pharmacy data to evaluate the percentage of fills and used a χ2 test to assess changes in percentage of fills. We used descriptive statistics and t tests to analyze changes in the number of prescriptions and changes in unique patients dispensed naloxone.

Results
We found a 2144% increase in the number of monthly naloxone prescriptions written after the alert became active. There was no statistically significant change in the percentage of fills. There was a 402.8% increase in unique patients statewide with a naloxone dispense after alert implementation.

Conclusions
Designing and implementing an electronic alert prompting naloxone coprescription are feasible and were associated with substantial increases in numbers of naloxone prescriptions and patients with naloxone dispenses statewide. Our findings expand on prior literature about electronic decision support for naloxone coprescription.
Efficacy of Microneedling With 35% Glycolic Acid Peels Versus Microneedling With 15% Trichloroacetic Acid Peels in Treatment of Atrophic Acne Scars: A Randomized Controlled Trial
Authors: Dayal Surabhi , Kaur Rupinder , Sahu Priyadarshini 
Published: November 2022

BACKGROUND
Combination of microneedling and chemical peeling is a simple cost-effective treatment for acne scars.

OBJECTIVE
To compare efficacy and safety of combining microneedling with 35% glycolic acid (GA) peel versus microneedling with 15% trichloroacetic acid (TCA) peel in facial atrophic acne scars.

METHODS
Forty acne scars patients were randomly divided into 2 groups of 20 each. Patients underwent microneedling followed by 35% GA peeling in Group 1 and 15% TCA peeling in Group 2 at 2 weekly intervals. Improvement was graded by Goodman and Baron's qualitative and quantitative global acne scar grading systems, physician's global assessment, and visual analogue scale (VAS). Skin texture was graded by VAS.

RESULTS
On comparing qualitative and quantitative acne scar grading within groups, there was significant difference from the baseline. When the two groups were compared for quantitative and qualitative acne scar grading, the difference was statistically not significant at the end of therapy. In VAS, greater number of patients assessed response as excellent and good in Group 1 than in Group 2 indicating better skin texture improvement in Group 1.

CONCLUSION
Both combinations were equally efficacious in treating acne scars. Glycolic acid peel delivered additional advantage of improvement in skin texture.
Primordial Prevention of Atherosclerotic Cardiovascular Disease
Authors: Morton Kara , Heindl Brittain , Clarkson Stephen , Bittner Vera 
Published: November 2022

Purpose:
The primordial prevention of atherosclerotic cardiovascular disease (ASCVD) involves the prevention of the onset of its risk factors. This review explores the associations between early modifiable risk factors and the development of ASCVD in adulthood, as well as evidence-based interventions to prevent them.

Review Methods:
A review was conducted on the basis of an in-depth literature search including longitudinal observational data, systematic reviews and meta-analyses published in 2012 or later, clinical trials, and additional manual searches of recent literature based on reference lists of other reviews and relevant guidelines.

Summary:
ASCVD is a disease that begins in childhood; hence, primordial prevention is an important target for improving cardiovascular morbidity and mortality later in life. Data from large-scale population studies have consistently identified the following modifiable risk factors for the development of ASCVD: smoking, overweight and obesity, high cholesterol, high blood pressure, hyperglycemia, poor diet, and physical inactivity. These risk factors originate during the prenatal, childhood, and adolescent stages of life. Various successful interventions to prevent the onset of each risk factor have been evaluated at the individual, community, and population levels. Implementation of a heart-healthy dietary pattern and regular exercise early in life are large components of many successful interventions.
Posterior Corneal Curvature Changes After Pre-Descemet's Endothelial Keratoplasty: A Prospective Analysis
Authors: Nidhi Kavya , Ashok Kumar Dhivya , Sinha Nisha , Agarwal Amar 
Published: November 2022

Purpose:
To assess the changes in the posterior corneal curvature after pre-Descemet's endothelial keratoplasty (PDEK) and correlate with the visual outcomes.

Methods:
Eyes with pseudophakic bullous keratopathy, aphakic bullous keratopathy, and Fuchs dystrophy undergoing PDEK were included. The main outcome measures were the topography (OrbscanIIz, Bausch and Lomb) indices—total corneal power (TCP) in diopters (D), radius of the posterior curvature (mm), and best-fit sphere of the posterior corneal surface (BFS in D) at preoperative and postoperative 1 month, 3 months, and 6 months.

Results:
Overall, 43 eyes of 43 patients with a mean age of 68 ± 9.6 years were studied. The mean preoperative TCP 43.1 D ± 2.3 reduced to 42.4 D ± 2.6 at 3 months (P < 0.010). There was a statistically significant decrease in the mean posterior corneal curvature at 1 month and 3 months postoperatively (P = 0.002). There was no significant change in the TCP and posterior corneal curvature at 6 months (P > 0.05). The mean BFS showed an increase at 1 month (53.45 ± 5.2 D) and 3 months (52.95 ± 5.1 D) and decrease at 6 months (51.90 ± 5.3 D). The overall change in BFS (P > 0.05) was not significant. There was significant improvement in visual acuity (P < 0.05). The best-corrected visual acuity was ≥20/40 in 79.07% and ≥20/60 in 100% at 6 months. There was no statistically significant correlation between the change in the best-corrected visual acuity and TCP, posterior corneal curvature, or BFS.

Conclusions:
Although there was immediate postoperative change in the posterior curvature, no significant change was induced by PDEK.
Effect of Increasing Povidone-Iodine Exposure on Corneal Epithelium and Impact on Donor Rim Cultures
Authors: Sawant Onkar B. , How Stephanie , Hurlbert Susan , Titus Michael S. , Vadakkepattath Indu , Shen Xiang , Djalilian Ali R. 
Published: November 2022

Purpose:
The purpose of this study was to assess the effect of a second povidone-iodine (PVP-I) application at the time of donor tissue recovery on overall tissue quality and to analyze the rate of positive fungal and bacterial rim cultures before and after implementing increased PVP-I exposure.

Methods:
The left cornea was recovered after a single application of PVP-I, while the right cornea was recovered after double PVP-I application in research-consented donors. The epithelial cell death rate was estimated using viability assay in corneal whole mounts under 10× objective (n = 5). Clinical characteristics of epithelium, stroma, and endothelium; positive rim culture rate; and incidences of infectious postoperative adverse reactions were compared for a period of 14 months before and after implementation of increased PVP-I protocol.

Results:
The average epithelial cell death rate was unaltered between single and double PVP-I exposure groups. We observed a modest 10% increase in the number of tissues with mild edema after implementation of increased PVP-I exposure. Nonetheless, the percentage of tissues with moderate or severe edema was unaltered. The average positive rim culture rate decreased from 1.17% to 0.88% (P = 0.075) after implementation of the double PVP-I soak procedure. There has been only one report of infectious postoperative adverse reactions since this procedure change. By contrast, there were 5 reports for a period of 14 months before implementation of this protocol.

Conclusions:
These results indicate that new donor preparation methods with an additional 5 minutes of PVP-I exposure do not affect tissue quality, reduce positive rim cultures, and lead to lower incidence of postoperative infection.
Feasibility of repeat microdissection testicular sperm extraction within 6 months for nonobstructive azoospermia
Authors: Tai Meng-Che , Huang I-Shen , Huang Chen-Yu , Huang William J. 
Published: November 2022

Background:
Microdissection testicular sperm extraction (mTESE) is the mainstay of sperm retrieval in men with nonobstructive azoospermia (NOA). Some experts believe that a resting period of ≥6 months is required between procedures to ensure better sperm retrieval rates and fewer complications. However, no scientific studies have investigated how long patients should wait before arranging a second mTESE procedure. This retrospective study aimed to evaluate whether good success rates are still achieved when a repeat mTESE procedure is performed within 6 months.

Methods:
Total 146 patients with NOA who underwent mTESE twice from the same testis between May 2012 and September 2019 were retrospectively collected. These patients were categorized into three groups according to the time interval between the two mTESE surgeries, with 44, 60, and 42 patients undergoing a repeat mTESE after <3 months (group I), between 3 and 6 months (group II), and >6 months (group III) after the first procedure, respectively.

Results:
No significant differences were observed between groups in terms of patient characteristics and preoperative hormone profiles. Overall sperm retrieval rates did not differ among the three groups (93.2%, 90.0%, and 88.1% in groups I, II, and III, respectively [p = 0.719]), nor did fertility outcomes, including rates of fertilization, biochemical pregnancy, clinical pregnancy, and cumulative live births.

Conclusion:
Sperm retrieval rates for repeat mTESE procedures were consistently high, even when the second procedure was performed within 6 months of the first. Repeat mTESE within 6 months is not a limitation for patients with NOA, if required clinically.
Bell's Palsy and Its Semantic Change over Time
Authors: Chern Alexander , Mudry Albert , Lustig Lawrence R. 
Published: November 2022

Background
From 1821 to 1829, Sir Charles Bell presented cases of facial paralysis from infection, trauma, and unknown causes. As such, “Bell's palsy” initially referred to facial palsy of any etiology. Today, the term is reserved for idiopathic peripheral facial palsy. The objectives of this analysis were to establish when the eponym came to vogue and delineate the semantic shift from its original definition to its current one.

Methods
Extensive review of available 19th and 20th century literature mentioning “Bell's palsy” and “Bell's paralysis.”

Results
Historical accounts have eponymously attached Bell's name to facial paralysis as early as the 1840s—Bell's palsy was first used to describe cases of facial palsy of any cause. In 1886, Gowers characterized Bell's palsy as a “neuritis usually within the Fallopian Canal,” distinguishing it as a separate etiology. Over the next decades, the definition narrowed to peripheral facial paralysis from cold exposure or unknown causes. By the 1940s, its natural history was well described—an acute, unilateral, idiopathic, and usually self-limited peripheral facial palsy.

Conclusion
The semantic change of a word over time can tell us a remarkable story of its history and origins. Absence of a discrete lesion, lack of proven treatment, and good prognosis without intervention distinguished Bell's palsy from other causes of facial paralysis. Over time, the definition has narrowed from a facial palsy of any cause to an idiopathic peripheral facial palsy. Recent evidence supporting Bell's palsy as a viral mononeuritis may have driven its recent semantic change toward this specific etiology.
Fracture neck of the talus with isolated talonavicular dislocation: A case report
Authors: Selim Amr , Naqvi Ali Zain , Magill Henry , Smith Jay 
Published: November 2022

Introduction:
Talar neck fractures are injuries which frequently result in adverse outcomes or impairment of functional activity. Four groups were identified according to Hawkins classification and Canale modification. We present a female patient with a fractured neck of the talus associated with talonavicular dislocation, but intact tibiotalar and subtalar joints; an injury pattern not fulfilling the criteria described in the Hawkins classification.

Patient concerns:
A 46-year-old woman missed a step and fell down stairs with an immediate painful right ankle and inability to bear weight.

Diagnosis:
Talar neck fracture with an unusual isolated talonavicular dislocation.

Interventions:
Temporary closed reduction followed by open reduction and internal fixation were performed.

Outcomes:
The patient had excellent functional and radiological outcomes following surgical management.

Conclusion:
We discuss the management of this rare case in addition to a review of the current literature to provide the best evidence-based recommendations for this injury pattern.