bluuebunny/crossref_metadata_2025_split huggingface dataset:
Caracterização das Conferências de Segurança Alimentar e Nutricional no estado da Bahia no período de 2007-2015
Authors: Souza Dejanira Alves de , Ramos Flávia Pascoal , Santos Sandra Maria Chaves dos 
Published: July 2022

O Sistema Nacional de Segurança Alimentar e Nutricional - SISAN, instituído em 2006, pressupõe a realização de conferências públicas em todas as esferas de governo. O estado da Bahia realizou cinco edições de Conferências de Segurança Alimentar e Nutricional (CSAN). O estudo objetivou caracterizar a dinâmica participativa de três edições das CSAN e as proposições emanadas a cada edição. Trata-se de estudo documental, que analisou os relatórios disponíveis das 3ª, 4ª e 5ª edições das CSAN realizadas nas etapas municipais, regionais, territoriais e estadual nos anos de 2007, 2011 e 2015, respectivamente. As proposições foram classificadas pelas dimensões da SAN (disponibilidade, acesso, consumo e utilização biológica de alimentos) e a dimensão transversal. Os resultados demonstraram: variação na dinâmica participativa dos municípios e territórios de uma edição para outra, com a 5ª edição, de 2015, registrando maior quantidade de municípios e 100% de participação dos territórios, sendo a mais propositiva das edições estudadas; todas as dimensões de SAN foram debatidas e contempladas nas três edições das CSAN; a 3ª edição realizada em 2007 foi a menos propositiva; a dimensão disponibilidade de alimentos obteve o maior número de proposições do total das três edições, seguida da dimensão consumo de alimentos. Conclui-se que as conferências geraram proposições relevantes para a formulação de políticas de interesse para a SAN na Bahia.
Reflexões sobre as metodologias ativas e tecnologias digitais como recursos pedagógicos no processo de ensino e aprendizagem de competências
Authors: Matos Simone Ribeiro , Mazzafera Bernadete Lema 
Published: July 2022

O processo de ensino e aprendizagem, tem-se ressignificado nas últimas décadas e com isso estratégias pedagógicas se fazem presentes nos currículos docentes. Assim, as metodologias ativas são ferramentas pedagógicas que contribuem com um ensino dinâmico, uma vez que o uso dessas estratégias metodológicas aliadas às tecnologias Digitais de Informação e Comunicação (TDIC) corroboram com a formação de um estudante autônomo e protagonista no ato de aprender. Nessa perspectiva, este estudo tem como objetivo tecer reflexões sobre o uso de metodologias ativas e TDIC no desenvolvimento de competências dos estudantes, destacando-se o papel do professor nesse processo. Para isso, realizou-se uma pesquisa bibliográfica com análise qualitativa dos dados. Sendo assim, os autores basilares são: Zabala e Arnau, Perrenoud, Carvalho, Freire, Marcuschi, entre outros que foram utilizados para fundamentar o ensino de competências a partir do uso de metodologias ativas aliados às TDIC. Verificou-se os benefícios de um ensino por meio de metodologias ativas, bem como o papel do professor na efetivação do processo proporcionando o ensino por meio do desenvolvimento de competências. Diante disso, foi possível perceber que o planejamento do professor a partir de metodologias ativas e o uso de TDIC, colabora com o desenvolvimento de competências significativas e com a formação de estudantes ativos, críticos, protagonistas e pesquisadores no ato de aprender a saber e fazer em sala de aula e no âmbito social.
Limites e possibilidades da aplicação da Gestão do Conhecimento em política pública de lazer
Authors: Melo Cristina Carvalho de , Couto Ana Cláudia Porfírio 
Published: July 2022

Tendo em vista a criação de políticas públicas para atendimento ao direito social ao lazer, o volume e a relevância do conhecimento produzido na implantação, torna-se importante pensar em estratégias para gerenciar os conhecimentos adquiridos nestes projetos. O objetivo desse estudo foi analisar os limites e as possibilidades da aplicação da Gestão do Conhecimento em uma política pública de lazer. Para tal, realizou-se uma pesquisa de abordagem qualitativa e os dados foram coletados através da metodologia survey. Os limites encontrados foram: “formação dos agentes”, “estrutura física”, “descontinuidade da equipe”, “tempo” e “falta de sistematização”. As possibilidades encontradas foram: “Sistematização”, “Continuidade e Complementaridade” e “Acesso às lições aprendidas”. Para cada um dos limites foram apontados caminhos para minimização e para cada possibilidade, formas de potencialização. Conclui-se que o Estado precisa encarar a Gestão do Conhecimento como uma estratégia capaz de qualificar as políticas públicas, considerando as necessidades e respostas do público beneficiário.
Pemeriksaan Refraksi Subjektif Pada Penderita Presbiopia Dengan Status Refraksi Hipermetropia Di Optik Pandanaran Semarang
Authors: Kholil Mochammad 
Published: July 2022

Gangguan penglihatan jauh dan dekat dapat terjadi oleh karena beberapa macam sebab, antara lain karena presbiopia yang berkorelasi dengan Hipermetropia. Tujuan penelitian ini adalah untuk mengetahui bagaimana prosedur pemeriksaan refraksi subjektif pada penderita presbiopia dengan kelainan refraksi hipermetropia yang benar. Penelitian ini dilaksanakan dengan menggunakan metode deskriptif melalui pendekatan studi kasus. Populasi dalam penelitian ini adalah kegiatan pemeriksaan refraksi subjektif yang tercatat dari rentang waktu 1 Desember 2021 s.d. 31 Januari 2022 di Optik Pandanaran Semarang. Hasil penelitian menunjukkan bahwa dari 369 pasien yang mengalami gangguan penglihatan di Optik Pandanaran adalah emmetropia 0%, miopia 46,7%, hipermetropia 13,8%, dan astigmatismus 25,7%. Dari jumlah tersebut diketahui 52% berusia <40 tahun dan 48% berusia ≥40 tahun. Berdasarkan jenis kelamin diketahui 46,7% berjenis kelamin laki - laki dan 53,3% berjenis kelamin perempuan. Simpulan Penetapan ukuran kacamata untuk penglihatan jauh bagi penderita Presbiopia dengan status refraksi Hipermetropia di Optik Pandanaran Semarang berlandaskan hasil koreksi visus binokuler terbaiknya.
Case Report: Two Patients With EGFR Exon 20 Insertion Mutanted Non-Small Cell Lung Cancer Precision Treatment Using Patient-Derived Xenografts in Zebrafish Embryos
Authors: Wang Qian , Wang Wenxian , Pan Weiwei , Lv Xiaojing , Zhang Lei , Zheng Kaiming , Tian Fang , Xu Chunwei 
Published: July 2022

BackgroundEpidermal growth factor receptor (EGFR) exon 20 insertion mutations are uncommon EGFR mutations and generally resistant to first- and second-generation EGFR-tyrosine kinase inhibitors (TKIs). In precision oncology, treatment regimens are tested for improving the clinical outcomes. Zebrafish embryo tumor transplant models are used in cancer research.MethodsWe report two Chinese females who were diagnosed with stage IV lung adenocarcinoma and shown to harbor EGFR exon 20 insertion mutations by next-generation sequencing (NGS). Then, we established lung cancer patient-derived xenografts using a zebrafish model. The tumor cells were isolated from the patient. For case one, tumor cells were collected from lymph node biopsy, while the tumor cells were obtained from the pleural effusion. Zebrafish were inoculated with tumor cells and placed in the culture medium containing the third-generation EGFR-TKI, osimertinib. Fluorescence microscope photographs were used to record the red fluorescence area, which represented the proliferation and migration of tumor cells in the zebrafish.ResultsCase one was diagnosed with lung adenocarcinoma (cT4N3M1b, stage IVB) and had an EGFR exon 20 mutation (p. N771delinsHH [abundance 14.08%]). Tumor cell proliferation and migration were significantly reduced in the osimertinib group compared with the control group. The patient received first-line osimertinib (160 mg). According to RECIST v1.1, she achieved a partial response. Case two had stage IVA lung adenocarcinoma with a pleural effusion. The pleural effusion sample was selected to obtain tumor cells for injection, and the zebrafish lung cancer model was established. The proliferation of tumor cells in the osimertinib group was significantly reduced compared to the control group. The migration of tumor cells was not significantly reduced compared to the control group. The patient also received first-line osimertinib (160 mg). The lung lesions were stable, but the pleural effusion was poorly controlled.ConclusionOur study demonstrates the applicability of a zebrafish embryos model as an innovative platform to targeted drug testing. More precise methods are needed to select treatment options in the future.
Simulation models for learning local skin flap design and execution: A systematic review of the literature
Authors: Hadjikyriacou Eleni , Goldsmith Thomas , Bowerman Frances I. , Dobbs Thomas D. , Whitaker Iain S. 
Published: July 2022

IntroductionEarly exposure to practical skills in surgical training is essential in order to master technically demanding procedures such as the design and execution of local skin flaps. Changes in working patterns, increasing subspecializations, centralization of surgical services, and the publication of surgeon-specific outcomes have all made hands-on-training in a clinical environment increasingly difficult to achieve for the junior surgeon. This has been further compounded by the COVID-19 pandemic. This necessitates alternative methods of surgical skills training. To date, there are no standardized or ideal simulation models for local skin flap teaching.AimThis systematic review aims to summarize and evaluate local skin flap simulation and teaching models published in the literature.Materials and MethodsA systematic review protocol was developed and undertaken in accordance with PRISMA guidelines. Key search terms encompassed both “local skin flaps” and “models” or “surgical simulation”. These were combined using Boolean logic and used to search Embase, Medline, and the Cochrane Library. Studies were collected and screened according to the inclusion criteria. The final included articles were graded for their level of evidence and recommendation based on a modified educational Oxford Center for evidence-based medicine classification system and assessed according to the CRe-DEPTH tool for articles describing training interventions in healthcare professionals.ResultsA total of 549 articles were identified, resulting in the inclusion of 16 full-text papers. Four articles used 3D simulators for local flap teaching and training, while two articles described computer simulation as an alternative method for local flap practicing. Four models were silicone based, while gelatin, Allevyn dressings, foam rubber, and ethylene-vinyl acetate-based local flap simulators were also described. Animal models such as pigs head, porcine skin, chicken leg, and rat, as well as a training model based on fresh human skin excised from body-contouring procedures, were described. Each simulation and teaching method was assessed by a group of candidates via a questionnaire or evaluation survey grading system. Most of the studies were graded as level of evidence 3 or 4.ConclusionMany methods of simulation for the design and execution of local skin flaps have been described. However, most of these have been assessed only in small cohort numbers, and, therefore, larger candidate sizes and a standardized method for assessment are required. Moreover, some proposed simulators, although promising, are in a very preliminary stage of development. Further development and evaluation of promising high-fidelity models is required in order to improve training in such a complex area of surgery.
Maria Glazovskaya—A Pioneer Soil Scientist and Geochemist Ahead of her Time (1912–2016)
Authors: Gerasimova Maria 
Published: July 2022

In the USSR and in Russia, women predominated among soil scientists despite the problems related to field research in tundra, taiga, mountains and other severe environments. One such woman was Maria Glazovskaya, who worked in highlands and semi-deserts studying little known soils, both recent and relict, primary pedogenesis, and geochemical features of hard rock weathering. Her scientific interests were diverse, and corresponded well with the social and scientific trends of the moment. She put forward new ideas and applied existing ones in several spheres of soil geography and landscape geochemistry. She proposed new approaches for compiling soil and landscape-geochemical maps, including using soil properties to predict the risks of soil pollution with heavy metals, and using landscape-geochemical methods to prospect for economic minerals. In the interdisciplinary conceptual sphere, Glazovskaya tried to bring together soil science and landscape geochemistry, and included these two subjects in the name of the department in Moscow University that she headed for more than 30 years. She was a scientist always looking for her own way in the interdisciplinary world of earth science.
Comparative Evaluations to Enhance Chemical and Microbial Quality of Salted Grey Mullet Fish
Authors: Khalifah Ayman M. , Badr Ahmed N. , El-Khadragy Manal F. , Shehata Mohammed G. , Abdalla Sara A. , Yehia Hany M. , Ali Hatem S. 
Published: July 2022

Salted fish preparations are popular and widely eaten across the world. Salting is a preservation strategy to enhance shelf life by decreasing water activity in fish muscles. Salted fish demand increases with less regard for preservation characteristics, and novel strategies are required for healthy production. Lysozyme, EDTA, their mixture, and black cumin oil nanoemulsion (BCN) were used for dipping treatments to make preservative films before salting. A medium-sized mullet were classified into six groups: fresh, commercial salted mullet, and four treatments. Stored salted mullet groups were evaluated for chemical composition changes, lipid profile changes, nitrogen profile changes, and microbial contamination. The results were reflected by nonsignificant changes in protein content (21.08 ± 1.05%) of the BCN compared to the fresh (22.41 ± 1.41%), with the lowest salt penetration to the flesh (11.11 ± 0.74%). The lowest value recorded was the BCN for the pH (5.53 ± 0.06) and water activity (0.447 ± 0.019). The changes in lipid profile compared to the fresh were very low, which does not happen in a commercial salted sample. The changes in total volatile and non-protein nitrogen represented very low for the BCN compared to the commercial salted one. Coliform, E. coli, Staphylococcus aureus, Salmonella, and Clostridium were not detected in the BCN salted mullet. The overall acceptability for the BCN mullet was the best in the test panel list evaluation, followed by the mixture treatment. This research indicated that the BCN treatment before mullet fish salting was optimal, with greater food safety properties and no consumer acceptance alterations.
A Machine Learning Model for Predicting Mortality within 90 Days of Dialysis Initiation
Authors: Rankin Summer , Han Lucy , Scherzer Rebecca , Tenney Susan , Keating Matthew , Genberg Kimberly , Rahn Matthew , Wilkins Kenneth , Shlipak Michael , Estrella Michelle 
Published: July 2022

Key Points

This paper presents an eXtreme Gradient Boosting (XGBoost) model that predicted mortality in the first 90 days after dialysis initiation using data from the United States Renal Data System.Such a model could facilitate patient-clinician shared decision making on whether to initiate dialysis or pursue medical management.The XGBoost models discriminated mortality risk in both the nonimputed (c=0.826) and imputed (c=0.827) models.

Background
The first 90 days after dialysis initiation are associated with high morbidity and mortality in end-stage kidney disease (ESKD) patients. A machine learning–based tool for predicting mortality could inform patient-clinician shared decision making on whether to initiate dialysis or pursue medical management. We used the eXtreme Gradient Boosting (XGBoost) algorithm to predict mortality in the first 90 days after dialysis initiation in a nationally representative population from the United States Renal Data System.

Methods
A cohort of adults initiating dialysis between 2008–2017 were studied for outcome of death within 90 days of dialysis initiation. The study dataset included 188 candidate predictors prognostic of early mortality that were known on or before the first day of dialysis and was partitioned into training (70%) and testing (30%) subsets. XGBoost modeling used a complete-case set and a dataset obtained from multiple imputation. Model performance was evaluated by c-statistics overall and stratified by subgroups of age, sex, race, and dialysis modality.

Results
The analysis included 1,150,195 patients with ESKD, of whom 86,083 (8%) died in the first 90 days after dialysis initiation. The XGBoost models discriminated mortality risk in the nonimputed (c=0.826, 95% CI, 0.823 to 0.828) and imputed (c=0.827, 95% CI, 0.823 to 0.827) models and performed well across nearly every subgroup (race, age, sex, and dialysis modality) evaluated (c>0.75). Across predicted risk thresholds of 10%–50%, higher risk thresholds showed declining sensitivity (0.69–0.04) with improving specificity (0.79–0.99); similarly, positive likelihood ratio was highest at the 40% threshold, whereas the negative likelihood ratio was lowest at the 10% threshold. After calibration using isotonic regression, the model accurately estimated the probability of mortality across all ranges of predicted risk.

Conclusions
The XGBoost-based model developed in this study discriminated risk of early mortality after dialysis initiation with excellent calibration and performed well across key subgroups.
Percepción de la enfermera sobre los cuidados brindados al paciente con COVID-19 en la unidad de cuidados intensivos
Authors: Irigoin Mazabel Jhon Elmy , Constantino Facundo Francisca 
Published: July 2022

Objetivo: describir analizar y comprender la percepción de la enfermera sobre los cuidados brindados al paciente con COVID-19 en la Unidad de Cuidados Intensivos, Chiclayo 2021. Método: el estudio fue de tipo cualitativa, con diseño descriptivo. La población lo conformaron 69 enfermeras de la UCI; la muestra estuvo constituida por 15 enfermeras de las cuales 8 fueron del Hospital Regional, 3 del Hospital Luis Heysen Incháustegui y 4 del Hospital Almanzor Aguinaga Asenjo; el tamaño de la muestra se determinó mediante un muestreo por conveniencia con técnica de bola de nieve. El instrumento fue una entrevista semiestructurada, previo consentimiento informado mediante la plataforma Zoom; la información fue analizada utilizando el método de análisis de contenido. En la investigación se consideraron los principios éticos y criterios científicos. Resultados principales: surgió como resultado tres categorías: I. Describiendo el cuidado personalizado e integral al paciente con COVID-19 en la UCI; II. Priorización de los cuidados basados en las necesidades del paciente con COVID-19 y III. Actitudes y sentimientos al cuidar del paciente con COVID-19. Conclusión general: los cuidados de enfermería son importantes, personalizados, exigentes, exhaustivos, dedicados y especializados, considerando al paciente con COVID-19 un ser pandimensional enfocándose en sus dimensiones físicas, emocionales y espirituales; comprometidas con su labor las enfermeras presentaron sentimientos de culpa, tristeza, ansiedad, estrés y preocupación por el contagio con actitudes positivas, empáticas y luchadoras.

Palabras clave: percepción, cuidado.
Descriptores: enfermera (D009726), COVID-19 (Infecciones por coronavirus) (D018352), cuidados intensivos (cuidados críticos) (D003422).
Fuente: DECS
Literatura de Cordel e Educação
Authors: Ribas Maria Cristina Cardoso , Malafaia Rosana da Silva 
Published: July 2022

Este estudo visa apresentar a literatura de cordel sob um viés artístico-literário. Para a análise buscamos uma perspectiva literária das Intermidialidades (Clüver, 2010; Diniz, 2012), estudando o cordel como processo de hibridização interartística e transcultural. Trazendo à tona essa complexidade composicional, o cordel ilumina o Ensino da Literatura Brasileira no contexto da Educação Básica (Vygotsky,1991), desenvolvendo, como eixo experiencial da nossa proposta, uma leitura em múltiplas conexões – literárias, artísticas, históricas. Os resultados apresentados até o momento, no Ensino Básico, demonstram o quanto a abordagem intermidiática abre o campo de visão do ledor, problematiza os critérios de validação da obra permitindo, a docente e discentes, desenvolver um novo olhar para a arte composicional da literatura de cordel e sua presença na formação cultural brasileira.
Viagem crítico-sentimental à 10ª Bienal de São Paulo e às outras edições
Authors: Coviello João 
Published: July 2022

O objetivo deste ensaio é analisar o papel da Bienal de São Paulo e retratá-la como um dos grandes eventos culturais do país desde sua primeira edição, em 1951. Apesar desta importância, sua face polêmica a acompanha desde então. A 1ª, a 10ª e a 28ª edições são modelos de importância e conflitos abordados neste ensaio. A 10ª, em especial, é observada através dos olhos de um espectador mirim, e considerada por ele como a maior exposição de todos os tempos, apesar de ser a mais criticada dentre todas as edições. Os dramas pessoais e morais que envolveram essa edição são analisados, bem como a experiência estética única vivida pelo fruidor mirim, personagem principal desta análise.
Gosto de sangue
Authors: Marques Henrique Rodrigues 
Published: July 2022

Através da análise fílmica comparativa de uma constelação de curtas e longas-metragens do cinema brasileiro contemporâneo, este artigo pretende explorar o modo como o gênero de horror é utilizado por uma nova geração de cineastas queer como maneira de representar o desejo sexual dissidente. Partindo de leituras queer sobre o horror gótico, analisaremos a recorrência do sangue nessas narrativas enquanto metáfora de abjeção e desejo, assim como a apropriação positiva da monstruosidade e suas implicações no panorama de produções audiovisuais que abordam o desejo homossexual no Brasil.

Palavras-chave: cinema queer; cinema brasileiro; cinema contemporâneo; horror; gótico.
Effects of sputtering with Kr gas and insertion of lowermost layer on electrical resistivity of Ag-multilayer
Authors: Mizukoshi Koji , Yamamura Takafumi , Tomioka Yasuhiro , Kawamura Midori 
Published: July 2022

Abstract
Silver-based low-emissivity films have been studied to improve window insulation performance. We have reduced the resistivity of Ag in glass/ZnO/Ag structures by inserting a TiO2 in the lowermost layer. In another study, we have also found that the resistivity of Ag thin film can be reduced by changing the sputtering gas from Ar to Kr. In this study, both methods were adapted to achieve even lower resistivity and the factors involved were analyzed in detail. The lowest electrical resistivity achieved was 3.3 μΩ·cm for a combination of a glass/TiO2/ZnO/Ag structure and Kr gas sputtering, which was 2.9% less than that for a glass/TiO2/ZnO/Ag structure with Ar gas sputtering. X-ray diffraction, atomic force microscopy, and secondary ion mass spectroscopy results indicated that the important factor influencing the electrical resistivity was a reduction in the amount of sputtering gas trapped in the Ag layer by depositing the layer using Kr gas.