bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study protocol: The SunBurst trial—a register-based, randomized controlled trial on thoracolumbar burst fractures
Authors: Blixt Simon , Mukka Sebastian , Försth Peter , Westin Olof , Gerdhem Paul ,   SunBurst study group
Published: February 2022

Background and purpose: The treatment for patients with thoracolumbar burst fractures without neurological deficit or complete rupture of the posterior ligament complex (PLC) is controversial and includes both surgical and non-surgical options. Current evidence on which treatment is optimal remains inconclusive. In this study we compare surgical with non-surgical treatment.
Methods: The study is a nationwide, multicenter, register-based randomized controlled trial (R-RCT). Patients with a thoracolumbar burst fracture will be identified by the Swedish Fracture Register. The admitting physician will be notified during the registration process and the patient will be screened for eligibility. Patients, 18 to 66 years old without neurologic deficit to more than a single nerve root and without complete rupture of the PLC, are eligible for the study. 202 patients will be randomized in a 1:1 relation to either surgical or non-surgical treatment. Patient-reported outcome measures (PROMs), including the Oswestry Disability Index(ODI) and radiological data, will be collected at the time of injury, after 3–4 months, and after 1 year. Additional data from national health registries will be collected after 1 year.
Outcome: The primary outcome is the ODI 1 year after injury. Secondary outcomes include additional PROMs, adverse events, drug consumption, sick leave, healthcare consumption, and imaging data.
Interpretation: The primary outcome is the ODI 1 year after injury. Secondary outcomes include additional PROMs, adverse events, drug consumption, sick leave, healthcare consumption, and imaging data. Estimated duration — The study started on September1, 2021 and will continue for approximately 4 years. Trial registration — The trial is registered at www.clinicaltrials.com, NCT05003180.
Pemanfaatan dan Skrining Fitokimia Infusa Daun Rumput Knop (Hyptis capitata Jacq.)
Authors: To'bungan Nelsiani 
Published: February 2022

Rumput Knop (Hyptis capitata Jacq.) banyak dimanfaatkan sebagai obat tradisional oleh masyarakat suku Toraja. Informasi ilmiah tentang pemanfaatan Rumput Knop dan kandungan metabolit sekundernya yang berkhasiat sebagai obat tradisional masih terbatas. Penelitian ini dilakukan untuk mengumpulkan informasi dari masyarakat suku Toraja mengenai khasiat Rumput Knop dalam mengatasi berbagai penyakit, variasi organ tumbuhan yang dimanfaatkan sebagai obat dan cara pengolahannya. Data pemanfaatan rumput knop diperoleh melalui wawancara. Untuk mendukung data khasiat, dilakukan uji fitokimia kualitatif meliputi uji alkaloid, triterpenoid, steroid, saponin, tannin dan flavonoid. Rumput knop diaplikasikan untuk beberapa penyakit seperti sakit perut, sakit kepala, demam dan luka terbuka. Organ tumbuhan yang sering digunakan dalam pengobatan adalah daun muda. Cara pengolahan yang paling banyak dilakukan adalah perebusan. Berdasarkan hasil tersebut, maka organ yang dipilih untuk dilakukan skrining fitokimia adalah daun dan metode ekstraksi metabolit sekundernya dengan metode infusa. Skrining fitokimia menunjukkan infusa daun Rumput Knop mengandung flavonoid, steroid dan tannin. Kata Kunci: Etnobotani, Infusa, rumput knop, nutrasetika
Pertumbuhan Mikroalga Chlamydomonas dalam Medium Beneck dan Air Tanah yang Mengandung Insektisida Berbahan Aktif Klorpirifos
Authors: Kurniasih M. , Prihantini N. B. , Nurtiyani E. 
Published: February 2022

The research of insecticide effect to the growth of genus Chlamydomonas had been done. Research was experimental study with block random design to 9 concentrations of chlorpiriphos containing insecticide in Beneck and soil water media i.e. 0 (control), 0.05, 0.10, 0.15, 0.20, 0.25, 0.30, 0.35, and 0.40%. Observations were done for 35 days. Friedman test showed that there were some effects of media and insecticide concentrations on cell numbers of Chlamydomonas (cell/ml) in culture (p>0.05). Dunnets test showed that mean of cell numbers of Chlamydomonas (cell/ml) differ (on p>0.05) and very differ (on p>0.01) on every concentrations in Beneck and soil water media. Insecticide could reduced the cell size of Chlamydomonas, yet increased the number of cells on 0.05--0.30% concentrations in Beneck medium, and 0.05--0.20% concentrations in soil water medium. On peak culture, insecticide with 0.10% concentration produced the highest cell numbers i.e. 21,179,167 cell/ml in Beneck medium, and 4,087,500 cell/ml in soil water medium.
Deteksi Secara Imunohistokimia Oxygen-Free Radical Scavenger-Copper, Zinc-Superoxide Dismutase (Cu,Zn-SOD) pada Hati Tikus di Bawah Kondisi Stress
Authors: Wresdiyati Tutik 
Published: February 2022

Copper,zinc-superoxide dismutase (Cu,Zn-SOD) yang merupakan salah satu oxygen-free radical scavenger telah dideteksi secara imunohistokimia pada hati tikus di bawah kondisi stres. Sejumlah empat puluh lima ekor tikus jantan galur Wistar telah digunakan pada penelitian ini. Hewan percobaan tersebut dikelompokkan menjadi tiga kelompok, yaitu : (1) kelompok kontrol, (2) kelompok dengan perlakuan stres selama 3 hari, dan (3) kelompok dengan perlakuan stres selama 5 hari. Stres yang diberikan adalah puasa, dengan pemberian air minum secara ad libitum. Stres yang diberikan menimbulkan keadaan histopatologis, peradangan dan nekrosis pada jaringan hati kelompok perlakuan tersebut. Secara imunohistokimia menunjukkan adanya penurunan kandungan Cu,Zn-SOD pada jaringan hati kelompok perlakuan dibandingkan pada kelompok kontrol. Penurunan kandungan Cu,Zn-SOD tersebut lebih hebat pada kelompok perlakuan selama 5 hari dibandingkan dengan kelompok perlakuan selama 3 hari. Hasil penelitian ini menunjukkan bahwa kondisi stres kemungkinan dapat meningkatkan terbentuknya oxygen-free radical yang kemudian merusak jaringan hati dan menurunkan kandungan Cu,Zn-SOD.
Perbaikan Budidaya Polikultur Lidah Buaya (Aloe vera Linn) dan Kacang Panjang (Vigna unguiculata) Menggunakan Biakan Rhizobium
Authors: Purwaningsih Sri , Saefudin Saefudin , Budiarjo Budiarjo 
Published: February 2022

Polyculture cultivation improvement of Aloe vera Linn (A. vera Linn) and Vigna unguiculata (V. unguiculata) has been done using Rhizobium strains inoculation onto V. unguiculata seeds to increase their growth and production. The study was done in Ciomas district, Bogor, using rice paddy field with a total of 24th plots of 1 x 2,5m2 width. A. vera Linn was planted until two months old using an interval of 60 x 60 cm2. The Rhizobium used were strains number 171, 172, 173, and their combination of those three, which was planted using an interval of 20 x 35 cm2. The negative controls were uninoculated, without N (K1) and the positive controls were uninoculated, with urea fertilizer equal to 100 kg/ha (K2). The experiment design was using Randomized Complete Block Design (RCBD) with four replications. The parameters used were leaves numbers, dry weight of plants, roots, root nodules, and pods production of V. unguiculata and leaves number, leaves length and width of A. vera. Results showed that isolate number of 172 (isolate of Glycine max Linn.) had given the best results on the production of V. unguiculata in the polyculture system with A. vera.
Depth structure of the Gorishne-Plavninsk structure and general principles of geological and geophysical study of the Krivoy Rog-Kremenchug iron-ore strip
Authors: Entin V. A. , Orlyuk M. I. , Belous O. I. , Gintov O.B. , Malakhov V.G. , Bakhmutov V.G. , Kachan I.A. , Bakarzhieva M.I. , Makarenko I.B. , Savchenko O.S. , Samoilenko T.M. , Marchenko A.V. , Drukarenko V.V. , Poliachenko I.B. , Mychak S.V. , Romenets A.O. , Braiko O.V. 
Published: February 2022

The article presents the results of the newest research performed by the State Enterprise «Ukrainian Geological Company» and the Institute of Geophysics of the National Academy of Sciences of Ukraine in 2021 to find out the morphology and elements of occurrence of an redeposit within the limits of the Gorishne-Plavninsk-Lavrikovsk area of the Krivoy Rog-Kremenchug iron-ore strip. In the process of geological and geophysical studies, a large body of new geological and geophysical data was obtained regarding the deep structural and morphological features of the construction of the Gorishne-Plavninsk structure (GPS), associated with the Krivoy-Rog deep fracture zone.
Materials of reinterpretation of previously per formed ground-based magnetometric and gravimetric surveys, detailed high-altitude aeromagnetic studies and the study of the density and magnetic properties of the structure rocks, including the anisotropy of magnetic susceptibility using new equipment and techniques, gravimagnetic modeling with the construction of three-dimensional volume model of the structure lead to the conclusion that this structure is a typical drag fold with a pronounced reversal of its southern part by the right-hands hear. Its primary formation occurred as a faulted band of sedimentary-volcanogenic and extrusive formations of subvertical bedding and spreading to a depth of at least 1.5—2 km.
A complete morphological and kinematic analogue of the GPS is the previously studied Likhmanovsk structure, located in the southern most part of the Krivoy Rog-Kremenchug strip. Many iron-ore structures of the Middle Bug area are close to it in structure and kinematics, the primary subvertical faulting and doubtful sedimentary genesis were mentioned earlier. All these data require a new approach to the study of iron-ore and some other deposits of the Ukrainian Shield associated with fault tectonics, as well as to the genesis problems and stratigraphy of rocks of the Early Precambrian.
Development and validation of a nomogram model for pneumonia after redo cardiac surgery
Authors: Wang Dashuai , Li Yixue , Sheng Weiyong , Wang Hongfei , Le Sheng , Huang Xiaofan , Du Xinling 
Published: February 2022

Aims
Postoperative pneumonia (POP) after redo cardiac surgery is prevalent, associated with poor outcome. The aim of this study was to identify independent risk factors for POP after redo cardiac surgery and to develop and validate a prediction model.

Methods
Adults undergoing redo cardiac surgery from 2016 to 2019 were identified in a single-institution database. Using a 2: 1 ratio, the patients were randomly divided into training and validation sets. Univariate and multivariate analyses were applied to identify independent predictors for POP in the training set. A nomogram model was constructed for clinical utility and was validated in the validation set.

Results
POP developed in 72 of the 376 patients (19.1%). Four independent risk factors were identified, including age, chronic obstructive pulmonary disease, serum creatinine level and intraoperative blood transfusion volume. A nomogram based on the four predictors was constructed, with good discrimination in both the training (c-index: 0.86) and validation sets (c-index: 0.78). The model was well calibrated, with a Hosmer-Lemeshow χ2-value of 7.31 (P
= 0.50) in the training set and 7.41 (P
= 0.49) in the validation set. The calibration was also good by visual inspection. The decision and clinical impact curves of the nomogram indicated good clinical utility. Three risk intervals were identified based on the nomogram for better risk stratification.

Conclusion
We developed and validated a nomogram model for POP after redo cardiac surgery. The model may have good clinical utility in risk evaluation and individualized treatment to reduce adverse events. Graphical abstract Incidence, risk factor, and outcomes of postoperative pneumonia after redo cardiac surgery: http://links.lww.com/JCM/A445.
Prompt gamma-ray methods for industrial process evaluation: A simulation study
Authors: Mohammed Mohammed Siddig H. , Alhawsawi Abdulsalam , Aljohani M. S. , Damoom Mohammed M. , Banoqitah Essam M. , Elmoujarkach Ezzat 
Published: February 2022

Abstract
Radioisotope applications in industrial process inspection and evaluation using gamma-ray emitters provide otherwise unavailable information. Offering alternative gamma-ray sources can support the technology by complementing sources’ availability and radiation safety. This work proposes to replace gamma-ray from radioisotopes with prompt gamma-ray from the interaction of neutrons with stable isotopes injected into the industrial process or with the structural material of the industrial process equipment. Monte Carlo N-Particle Transport Code (MCNP5) was used to simulate the irradiation of two-phase flow pipes by 252Cf neutron source. Two simulations were run for each pipe, with and without mixing the liquid phase with the stable isotope 157Gd. The detected gamma-ray spectra were analysed, and images of the two phases inside the pipes were produced. The images were compared to images obtained from simulations of gamma transmission measurement using 60Co. Furthermore, results for prompt gamma computed tomography (CT) were presented and discussed. The studies’ outcomes indicate the potential of prompt gamma-ray to carry out the sealed sources applications of gamma transmission measurements and imaging.
[RE]IMAJI GLODOK MELALUI ECHOLOGY
Authors: Wijaya Vito , Gandha Maria Veronica 
Published: February 2022

An Architecture can be a memory store from a time. Many buildings or areas that have historical value are now abandoned, disintegrated, eroded by modern developments. In line with the development of the city, there are many dark histories and political issues that afflict Chinese culture and society in Indonesia. With the revocation of Presidential Instruction No. 14/1967 concerning Chinese Religion, Belief, and Customs during the Reformation period, it was replaced by the issuance of Presidential Decree (Keppres) No. 6/2000 on January 17, 2000, bringing Chinese culture back to life, then how can an Architecture and a Chinatown be able to adapt to the conditions of today and for the future without losing its identity and historical value. This project is a new embodiment for an area that includes various elements such as history, culture, economy, utilities, and education. All these aspects are formed collectively and in a community with a narrative method and connect existing elements into the concept of Echology. [RE]Image Glodok produces a project that reimagines the Chinatown area of Glodok where historical, cultural, and economic aspects can be reflected and build a new Glodok image by considering various elements that exist in the area and designing it for the sake of sustainability in the present and the future through Echology. Keywords: Chinatown; Glodok; Image AbstrakSebuah Arsitektur dapat menjadi penyimpan memori dari suatu masa. Banyaknya bangunan atau kawasan yang memiliki nilai historis kini terbengkalai, terdisintegrasi, tergerus perkembangan moderen. Sejalan dengan perkembangan kota, banyak nya sejarah kelam dan isu-isu politik yang menimpa budaya serta masyarakat Tionghua di Indonesia. Dengan dicabutnya Inpres Nomor 14 Tahun 1967 tentang Agama, Kepercayaan, dan Adat Istiadat Cina pada masa Reformasi digantikan dengan terbitnya Keputusan Presiden (Keppres) Nomor 6 Tahun 2000 pada 17 Januari 2000 membuat budaya Tionghua kembali hidup, kemudian bagaimana sebuah Arsitektur dan sebuah kawasan Pecinan mampu menyesuaikan dengan kondisi pada zaman ini dan untuk masa depan tanpa kehilangan jati diri serta nilai sejarahnya. Proyek ini merupakan perwujudan baru bagi sebuah kawasan yang mencakup berbagai unsur seperti sejarah, budaya, ekonomi, utilitas, serta edukasi. Semua aspek tersebut dibentuk secara kolektif dan berkomunitas dengan metode naratif serta mengkoneksikan elemen-elemen yang sudah ada menjadi konsep Echology. [RE]Imaji Glodok menghasilkan sebuah proyek yang mereimajikan kawasan pecinan Glodok dimana aspek sejarah, budaya dan ekonomi dapat tercerminkan dan membangun imaji Glodok yang baru dengan mempertimbangkan berbagai elemen yang ada pada kawasan serta merancangnya demi keberlangsungan di masa kini maupun masa depan melalui Echology.
PERLUASAN HUTAN KOTA DAN EXPLORATORIUM ALAM DI PAMULANG
Authors: Ferari Fila , Winata Tony 
Published: February 2022

Earth is home to all living things in it which consists of various kinds of forming elements such as water, air, soil, temperature, light, humidity, humans, flora, fauna, and others. Life is the result of the interaction between fellow living things with their environment, which is called ecology. Architecture exists as a place, habitat, and niche for all living things to develop and grow. Cities are evidence of human evolution in which they can meet all the needs of life, and without realizing this development has led to the overpopulation phenomenon. This goes hand in hand with the land crisis and the loss of urban forest (green open space) as a result of this phenomenon. This project aims to re-elevate and enhance the essence of urban forests and become green generators in cities experiencing green open space crises, in order to maintain the balance of ecosystems and the environment. This will be achieved by going beyond the role played by urban forests and humans in general to create a greater impact on life. This is facilitated by habitats for plants and animals, sports activities, study rooms, playgrounds, fishing, and etc. Keywords: environment; exploratorium; green open space crisis; habitat; urban forestAbstrak Bumi merupakan rumah bagi semua makhluk hidup di dalamnya yang terdiri dari berbagai macam unsur pembentuk seperti air, udara, tanah, suhu, cahaya, kelembaban, manusia, flora, fauna, dan lain-lain. Kehidupan yang terjadi merupakan wujud hasil dari hubungan interaksi antara sesama makhluk hidup maupun dengan lingkungannya, yang disebut dengan ekologi. Arsitektur hadir sebagai wadah, habitat dan relung bagi semua makhluk hidup untuk berkembang dan bertumbuh. Kota merupakan bukti dari evolusi manusia yang di dalamnya dapat memenuhi semua kebutuhan kehidupan, dan tanpa disadari perkembangan ini mendorong terjadinya fenomena over population. Hal tersebut berjalan seiring dengan krisis lahan dan hilangnya hutan kota (RTH) akibat dari fenomena yang terjadi. Proyek ini bertujuan untuk mengangkat kembali dan meningkatkan esensi hutan kota, serta menjadi generator hijau di kota yang mengalami krisis RTH demi menjaga keseimbangan ekosistem dan lingkungan hidup. Hal ini dicapai dengan melampaui peran yang dimiliki oleh hutan kota dan manusia pada umumnya untuk menciptakan dampak yang lebih besar bagi kehidupan. Hal ini difasilitasi dengan habitat bagi tumbuhan dan hewan, kegiatan berolahraga, ruang belajar, bermain, memancing, dan sebagainya.
PENATAAN KAWASAN WISATA PANTAI GESING KECAMATAN PANGGANG, KABUPATEN GUNUNGKIDUL, YOGYAKARTA
Authors: Yosephine Hana Grace , Wipranata Irwan , Wirawati Sylvie 
Published: February 2022

The Gesing Beach tourist area is one of the tourist destinations in Gunungkidul Regency and is managed by the Gunungkidul Regency Tourism Office. The Gesing Beach tourist area was inaugurated in 2017, Gesing Beach is a beach with a landscape shape in the form of white sand beaches, hills and beaches. This tourist area is unique in its small waves and soft and light cream colored beach sand. The existing condition of the Gesing Beach Tourism Area which has natural scenery and good natural conditions, as well as its own uniqueness. However, the available potential cannot be utilized optimally because it does not yet have the facilities, facilities and infrastructure that support existing activities and potentials. In addition, the manager of the Gesing Beach tourist area has not promoted this tourist area so that there are still many visitors who do not know this tourist area, besides the lack of information makes this tourist area not widely known to people. The Gesing Beach tourist area still does not have adequate facilities, facilities and infrastructure such as trash cans, gazebos, souvenir shops, guest houses, directional signs, street lights, telecommunications networks, clean water, etc. existing facilities, build the required facilities and infrastructure. Keywords: Facilities; Facilities and Infrastructure; Promotion; Coastal Planning AbstrakKawasan wisata Pantai Gesing merupakan salah satu destinasi wisata yang berada di Kabupaten Gunungkidul dan dikelolah oleh Dinas Pariwisata Kabupaten Gunungkidul. Kawasan wisata Pantai Gesing diresmikan pada tahun 2017, Pantai Gesing adalah pantai dengan bentuk bentang alam berupa pantai pasir putih, bukit dan pantai kawasan wisata ini memiliki keunikan pada ombak yang kecil dan pasir pantai yang halus serta berwarna krem terang. Kondisi eksisting dari Kawasan Wisata Pantai Gesing yang memiliki pemandangan alam dan kondisi alam yang baik, serta keunikan tersendiri. Namun, potensi yang tersedia belum dapat dimanfaatkan secara optimal karena belum memiliki fasilitas, sarana dan prasarana yang mendukung kegiatan dan potensi yang ada. Selain itu, pengelola kawasan wisata Pantai Gesing belum melakukan promosi untuk kawasn wisata ini sehingga masih banyak pengunjung yang tidak mengetahui kawsan wisata ini, selain itu minimnya informasi semakin membuat kawasan wisata ini tidak banyak diketahui pengunjung. Kawasan wisata Pantai Gesing masih belum memiliki fasilitas, sarana dan prasarana yang memadai seperti tempat sampah, gazebo, kios souvenir, guest house, rambu petunjuk arah, lampu jalan, jaringan telekomunikasi, air bersih dll sehingga kawasan wisata Pantai Gesing memerlukan penataan untuk menata dan memperbaiki fasilitas yang telah ada, membangun fasilitas serta sarana dan prasarana yang dibutuhkan.
Propiedades psicométricas del instrumento Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12) en mujeres chilenas
Authors: Bascur-Castillo Carolina , Neisser Palominos Roberto , Pérez-Villalobos Cristhian , Carrasco-Portiño Mercedes 
Published: February 2022

Introducción:
Las disfunciones del piso pélvico impactan la función sexual de mujeres que la padecen. En un estudio chileno un 74% de las mujeres presentó disfunción sexual sin tener un instrumento validado para esta población.

Objetivo:
Evaluar las propiedades psicométricas del Pelvic Organ Prolapse Urinary Incontinence Sexual Questionnaire (PISQ-12) para medir la función sexual en mujeres chilenas con disfunciones del piso pélvico.

Métodos:
Estudio transversal psicométrico de 217 mujeres con disfunción del piso pélvico, igual /mayor a 18 años, sexualmente activas (últimos 6 meses). Muestreo no probabilístico de conveniencia. Cuestionario: PISQ-12. Se realizó juicio de expertos para validez de contenido, análisis factorial confirmatorio para validez de constructo y el α de Cronbach para confiabilidad y capacidad discriminativa con Pearson y ω de McDonald.

Resultados:
Población principalmente perimenopáusica, alta escolaridad sin ingresos y con Incontinencia Urinaria (89.4%). El análisis psicométrico apoyó una estructura de tres factores: respuesta sexual, limitaciones sexuales femeninas y limitaciones sexuales masculinas, con confiabilidad buena (α= 0.85) aceptable (α= 0.73) y pobre (α= 0.63), respectivamente, aunque el ω de McDonald mostró valores aceptables para los tres. Éstos se relacionaron con edad (rs: -0.33), escolaridad (0.36), número de embarazos (-0.18) y partos vaginales (-0.25).

Conclusiones:
El PISQ-12 es válido y confiable, midiendo la dimensión sexual y limitaciones sexuales. La edad, escolaridad, número de embarazos y partos vaginales se correlaciona con la respuesta sexual en intensidad moderada.