bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrable quantum many-body sensors for AC field sensing
Authors: Mishra Utkarsh , Bayat Abolfazl 
Published: August 2022

AbstractQuantum sensing is inevitably an elegant example of the supremacy of quantum technologies over their classical counterparts. One of the desired endeavors of quantum metrology is AC field sensing. Here, by means of analytical and numerical analysis, we show that integrable many-body systems can be exploited efficiently for detecting the amplitude of an AC field. Unlike the conventional strategies in using the ground states in critical many-body probes for parameter estimation, we only consider partial access to a subsystem. Due to the periodicity of the dynamics, any local block of the system saturates to a steady state which allows achieving sensing precision well beyond the classical limit, almost reaching the Heisenberg bound. We associate the enhanced quantum precision to closing of the Floquet gap, resembling the features of quantum sensing in the ground state of critical systems. We show that the proposed protocol can also be realized in near-term quantum simulators, e.g. ion-traps, with a limited number of qubits. We show that in such systems a simple block magnetization measurement and a Bayesian inference estimator can achieve very high precision AC field sensing.
Local structure elucidation of tungsten-substituted vanadium dioxide (V$$_{1-x}$$W$$_x$$O$$_2$$)
Authors: Wilson Catrina E. , Gibson Amanda E. , Cuillier Paul M. , Li Cheng-Han , Crosby Patrice H. N. , Trigg Edward B. , Najmr Stan , Murray Christopher B. , Jinschek Joerg R. , Doan-Nguyen Vicky 
Published: August 2022

AbstractInitially, vanadium dioxide seems to be an ideal first-order phase transition case study due to its deceptively simple structure and composition, but upon closer inspection there are nuances to the driving mechanism of the metal-insulator transition (MIT) that are still unexplained. In this study, a local structure analysis across a bulk powder tungsten-substitution series is utilized to tease out the nuances of this first-order phase transition. A comparison of the average structure to the local structure using synchrotron x-ray diffraction and total scattering pair-distribution function methods, respectively, is discussed as well as comparison to bright field transmission electron microscopy imaging through a similar temperature-series as the local structure characterization. Extended x-ray absorption fine structure fitting of thin film data across the substitution-series is also presented and compared to bulk. Machine learning technique, non-negative matrix factorization, is applied to analyze the total scattering data. The bulk MIT is probed through magnetic susceptibility as well as differential scanning calorimetry. The findings indicate the local transition temperature ($$T_c$$Tc) is less than the average$$T_c$$Tcsupporting the Peierls-Mott MIT mechanism, and demonstrate that in bulk powder and thin-films, increasing tungsten-substitution instigates local V-oxidation through the phase pathway VO$$_2\, \rightarrow$$2→V$$_6$$6O$$_{13} \, \rightarrow$$13→V$$_2$$2O$$_5$$5.
Influence of nanoparticles on freezing inside container equipped with fins
Authors: Almarashi Adel , Hussin Amira M. , Mirparizi M. , Zhang Chunwei , Saad Hosam A. 
Published: August 2022

AbstractWith loading of different shapes of nanoparticles, the solidification speed can be changed which was scrutinized in current work. Although the nanoparticles dispersion can decline the heat capacity, the conduction mode can be improved with such technique and changing the styles of nano-powders can alter the strength of conduction. The velocity terms were neglected in freezing, thus, the main equations include two equations with unsteady form for scalars of solid fraction and temperature. Grid adaption with position of ice front has been considered in simulations utilizing FEM. The upper sinusoidal and inner rectangular walls maintain cold temperature and freezing starts from these regions. Adding nanomaterial can expedite the process around 15.75% (for m = 4.8) and 29.8% (for m = 8.6). Also, utilizing particles with shapes of blade form can augment the freezing rate around 16.69%. The efficacy of m on freezing process rises around 4% with elevate of concentration of nanoparticles.
Risk factors for early-onset exfoliation syndrome
Authors: Park Do Young , Jeong Seongyong , Cha Soon Cheol 
Published: August 2022

AbstractAlthough exfoliation syndrome (XFS) is an age-related, late-onset disease, early-onset XFS has been reported, and its associated factors remain unknown. In this study, we investigated the clinical features and risk factors of early-onset XFS. The participants were divided into two groups according to age at the time of XFS diagnosis: early-onset (< 60 years) or late-onset (≥ 70 years) group. Among the 302 eyes of 240 patients with XFS, the early-onset group included 41 eyes (14%) of 33 patients, and the late-onset group included 163 eyes (54%) of 126 patients; the mean age was 54.8 ± 5.0 and 76.6 ± 4.9 years, respectively (p < 0.001). All eight cases diagnosed with XFS at the earliest age, ranging from 36 to 52 years, underwent trabeculectomy before the diagnosis of XFS. Multivariable logistic regression analysis showed that a history of trabeculectomy (odds ratio [OR] = 11.435, p < 0.001), presence of iridectomy (OR = 11.113, p < 0.001), and longer axial length (OR = 2.311, p = 0.003) were significantly associated with the development of early-onset XFS. Collectively, patients with early-onset XFS were more likely to have undergone trabeculectomy and have more axial myopia compared with those with late-onset XFS. These findings suggest that surgical trauma compromising the blood-aqueous barrier may trigger early manifestation of XFS.
Designated functional microcapsules loaded with green synthesis selenium nanorods and probiotics for enhancing stirred yogurt
Authors: El-Sayed Hoda S. , El-Sayed Samah M. , Youssef Ahmed M. 
Published: August 2022

AbstractGreen synthesis selenium nanorods (Se-NRs) were produced based on Aloe vera leaf extract. The size, morphology, antimicrobial, and activation of Se-NRs for probiotics were analyzed. The Se-NRS was stable with a diameter of 12 and 40 nm, had an antimicrobial effect, and improved probiotics counts. The microcapsules loaded with Green Se-NRS (0, 0.05 or 0.1 mg/100 ml) and probiotics (Bifidobacterium lactis and Lactobacillus rhamnosus) were designated with efficiency between 95.25 and 97.27% and irregular shapes. Microcapsules were saved probiotics against gastrointestinal juices. The microcapsules were showed a minor inhibition effect against the cell line. Also, microcapsules integrated into stirred yogurt and exanimated for microbiology, chemically, and sensory for 30 days. The probiotics counts, acidity, total solids, and ash values of samples were increased during storage periods without affecting fat and protein contents. The overall acceptability of yogurt with microcapsules containing probiotics and Se-NRs was high without change in body, odor, color, and appearance.
Effects of splenectomy on skin inflammation and psoriasis-like phenotype of imiquimod-treated mice
Authors: Shinno-Hashimoto Hiroyo , Eguchi Akifumi , Sakamoto Akemi , Wan Xiayun , Hashimoto Yaeko , Fujita Yuko , Mori Chisato , Hatano Masahiko , Matsue Hiroyuki , Hashimoto Kenji 
Published: August 2022

AbstractImiquimod (IMQ) is widely used as animal model of psoriasis, a chronic inflammatory skin disorder. Although topical application of IMQ to back skin causes splenomegaly in mice, how the spleen affects the psoriasis-like phenotype of IMQ-treated mice remains unclear. In this study, we analyzed the cellular composition of spleen and measured metabolites in blood of IMQ-treated mice. We also investigated whether splenectomy influences the degree of skin inflammation and pathology in IMQ-treated mice. Flow cytometry showed that the numbers of CD11b+Ly6c+ neutrophils, Ter119+ proerythroblasts, B220+ B cells, F4/80+ macrophages, and CD11c+ dendritic cells in the spleen were significantly higher in IMQ-treated mice compared to control mice. An untargeted metabolomics analysis of blood identified 14 metabolites, including taurine and 2,6-dihydroxybenzoic acid, whose levels distinguished the two groups. The composition of cells in the spleen and blood metabolites positively correlated with the weight of the spleen. However, splenectomy did not affect IMQ-induced psoriasis-like phenotypes compared with sham-operated mice, although splenectomy increased the expression of interleukin-17A mRNA in the skin of IMQ-treated mice. These data suggest that the spleen does not play a direct role in the development of psoriasis-like phenotype on skin of IMQ-treated mice, though IMQ causes splenomegaly.
Preliminary forensic assessment of the visualised fingerprints on nonporous substrates immersed in water using the green and optimised novel nanobio-based reagent
Authors: Azman Aida Rasyidah , Mahat Naji Arafat , Abdul Wahab Roswanira , Ahmad Wan Azlina , Ismail Dzulkiflee 
Published: August 2022

AbstractThe discovery of forensic evidence (e.g. weapons) during forensic underwater investigations has seen an increasing trend. To date, small particle reagent (SPR) has been one of the routinely used methods for visualising fingerprints on wet, non-porous substrates. However, the long term use of SPR is detrimental to humans and environment due to the use of toxic chemicals. Although previously we have successfully developed and optimised a greener nanobio-based reagent (NBR), its suitable practical use in a more realistic scene (e.g. outdoor pond) was not evaluated. Therefore, this present research is aimed at (1) investigating the performance of NBR against the benchmark SPR in visualising fingerprints immersed in a natural outdoor pond and (2) evaluating the greenness of NBR against the analytical Eco-Scale. Results showed that the performance of the optimised NBR was mostly comparable (University of Canberra (UC) comparative scale: 0) with SPR at visualising fingerprints on three different non-porous substrates immersed in a natural outdoor pond. Observably, the NBR had higher preference towards aged fingerprints (up to 4 weeks of immersion). In addition, its greenness assessment revealed 76 points, indicating ‘excellent green analysis’. The findings gathered here further supported the practical use of the NBR in forensic investigations.
MicroRNA profiling of subcutaneous adipose tissue in periparturient dairy cows at high or moderate body condition
Authors: Sadri Hassan , Ghaffari Morteza Hosseini , Trakooljul Nares , Ceciliani Fabrizio , Sauerwein Helga 
Published: August 2022

AbstractA growing body of evidence shows that microRNA (miRNA), play important roles in regulating adipose tissue (AT) physiology and function. The objective was to characterize the AT miRNA profile in over-conditioned (HBCS, n = 19) versus moderate-conditioned (MBCS, n = 19) periparturient dairy cows. Tail-head subcutaneous AT biopsied on d -49 and 21 relative to parturition were used for miRNA sequencing. The miR-486 was the most significant miRNA among the upregulated miRNA on d -49, which might be related to more pronounced changes in lipogenesis and altered insulin sensitivity in AT of HBCS cows at dry-off. Comparing HBCS to MBCS on d 21, 23 miRNA were downregulated and 20 were upregulated. The predicted targets of upregulated differentially expressed (DE)-miRNA on d 21 were enriched in different pathways, including pathways related to lysosomes and peroxisomes. The predicted targets of downregulated DE-miRNA on d 21 were enriched in various pathways, including epidermal growth factor receptor, insulin resistance, hypoxia-inducible factor 1 signaling pathway, and autophagy. The results showed that over-conditioning was associated with changes in SCAT miRNA profile mainly on d 21, of which most were downregulated. The enriched pathways may participate in over-conditioning-associated metabolic challenges during early lactation.
Glucocorticoids’ treatment impairs the medium-term immunogenic response to SARS-CoV-2 mRNA vaccines in Systemic Lupus Erythematosus patients
Authors: Garcia-Cirera Silvia , Calvet Joan , Berenguer-Llergo Antoni , Pradenas Edwards , Marfil Silvia , Massanella Marta , Mateu Lourdes , Trinité Benjamin , Llop Maria , Arévalo Marta , Galisteo Carlos , Orellana Cristóbal , Gómez Rafael , Gómez-Gerique María Nieves , Carmona Inma , Clotet Bonaventura , Blanco Julià , Gratacós Jordi 
Published: August 2022

AbstractLimited data exists on SARS-CoV-2 sustained-response to vaccine in patients with rheumatic diseases. This study aims to evaluate neutralizing antibodies (nAB) induced by SARS-CoV-2 vaccine after 3 to 6 months from administration in Systemic Lupus Erythematosus (SLE) patients, as a surrogate of sustained-immunological response. This cross-sectional study compared nAB titre of 39 SLE patients and 37 Healthy individuals with no previous SARS-CoV-2 infection, who had all received a complete regimen of a mRNA SARS-CoV-2 vaccine within the last 3 to 6 months. We included four lines of SLE treatment including Not-treated, Hydroxychloroquine, immunosuppressive drugs and biological therapy. Glucocorticoids were allowed in all groups. Healthy and Not-treated individuals showed the highest levels of nAB. Treated patients presented lower nAB titres compared to Healthy: a 73% decrease for First-Line patients, 56% for Second-Line treatment and 72% for Third-Line. A multivariate analysis pointed to Glucocorticoids as the most associated factor with declining nAB levels (75% decrease) in treated SLE. Furthermore, a significant reduction in nAB titres was observed for Rituximab-users compared to Healthy subjects (89% decrease). Medium-term response of SLE patients to SARS-CoV-2 mRNA vaccines is negatively impacted in Glucocorticoids and Rituximab users. These findings might help to inform recommendations in vaccination protocols for SLE patients.
The Ntan1 gene is expressed in perineural glia and neurons of adult Drosophila
Authors: Castañeda-Sampedro Ana , Calvin-Cejudo Laura , Martin Fernando , Gomez-Diaz Carolina , Alcorta Esther 
Published: August 2022

AbstractThe Drosophila Ntan1 gene encodes an N-terminal asparagine amidohydrolase that we show is highly conserved throughout evolution. Protein isoforms share more than 72% of similarity with their human counterparts. At the cellular level, this gene regulates the type of glial cell growth in Drosophila larvae by its different expression levels. The Drosophila Ntan1 gene has 4 transcripts that encode 2 protein isoforms. Here we describe that although this gene is expressed at all developmental stages and adult organs tested (eye, antennae and brain) there are some transcript-dependent specificities. Therefore, both quantitative and qualitative cues could account for gene function. However, widespread developmental stage and organ-dependent expression could be masking cell-specific constraints that can be explored in Drosophila by using Gal4 drivers. We report a new genetic driver within this gene, Mz317-Gal4, that recapitulates the Ntan1 gene expression pattern in adults. It shows specific expression for perineural glia in the olfactory organs but mixed expression with some neurons in the adult brain. Memory and social behavior disturbances in mice and cancer and schizophrenia in humans have been linked to the Ntan1 gene. Therefore, these new tools in Drosophila may contribute to our understanding of the cellular basis of these alterations.
Canted antiferromagnetic order in EuZn2As2 single crystals
Authors: Bukowski Zbigniew , Rybicki Damian , Babij Michał , Przewoźnik Janusz , Gondek Łukasz , Żukrowski Jan , Kapusta Czesław 
Published: August 2022

AbstractCompounds containing Eu show a vast range of unique physical properties due to the interplay of electronic and magnetic properties, which can lead to a nontrivial electronic topology combined with magnetic order. We report on the growth of trigonal ($$P\overline{3 }m1$$

P

3
¯

m
1

space group) EuZn2As2 single crystals and on the studies of their structural, electronic and magnetic properties. A range of experimental techniques was applied including X-ray diffraction, electron microscopy, magnetic susceptibility, magnetization, heat capacity and Mössbauer spectroscopy in the study. We found that Eu has solely a 2+ valence state and its magnetic moments below TN = 19.2 K form a canted antiferromagnetic structure, tilted from the basal plane.
Visual field examinations using different strategies in Asian patients taking hydroxychloroquine
Authors: Kim Ko Eun , Ryu So Jung , Kim Young Hwan , Seo Yuchan , Ahn Seong Joon 
Published: August 2022

AbstractIn this study, we investigated the patterns of visual field (VF) defects and the diagnostic abilities of VF tests using different strategies in Asian patients with hydroxychloroquine retinopathy. Patients screened for hydroxychloroquine retinopathy using optical coherence tomography, fundus autofluorescence, VF, and/or multifocal electroretinography were included. The VF was performed using the Humphrey 30-2 and/or 10-2 strategy, and 2,107 eyes of 1,078 patients with reliable results, including 136 eyes of 68 patients with hydroxychloroquine retinopathy, were analyzed. The characteristics of VF findings were evaluated and the sensitivity and specificity were compared between the 30-2 and 10-2 tests in subgroups of retinopathy severity and pattern. The most common VF defect pattern was partial- or full-ring scotoma in both the 10-2 and 30-2 tests. Among the eyes with hydroxychloroquine retinopathy that underwent both tests, 14.2% showed a disparity between the two tests, almost all at the early stage. In overall and early pericentral retinopathy, the sensitivity of the 30-2 test was significantly higher than that of the 10-2 test (95.7% vs. 77.1% and 90.6% vs. 53.1%, respectively; P < 0.05). However, the specificity of the 10-2 test was significantly higher than that of the 30-2 test (89.6% vs. 84.8%, P < 0.001). Therefore, the pattern of retinopathy should be carefully considered when choosing a VF strategy for better detection of hydroxychloroquine retinopathy.
Improved extraction efficiency of CsPbBr3 perovskite light-emitting diodes due to anodic aluminum oxide nanopore structure
Authors: Chen Lung-Chien , Kao Chien-Hong 
Published: August 2022

AbstractIn this work, we investigate the improvement in the performance of a CsPbBr3 perovskite light-emitting diode (PeLED) due to an anodic aluminum oxide (AAO) nanopore structure. The AAO structure in the CsPbBr3 PeLED structure can improve the light extraction efficiency of CsPbBr3 PeLEDs in two ways: the emission light in the side direction being redirected to the normal direction due to the light scattering effect caused by aluminum oxide nanopores and the effective emission area as a result of the rough surface of the AAO structure. The peak luminance, current efficiency, and external quantum efficiency (EQE) were 11,460 cd/m2, 2.03 cd/A, and 0.69% at a bias of 6.0 V, respectively. For comparison, the luminance, current efficiency, and EQE values of CsPbBr3 PeLEDs with the AAO structure using 50 V of pore-expanding voltage demonstrated improvements of 282%, 190%, and 1280%, respectively, over CsPbBr3 PeLEDs without the AAO structure.
Selection of seismic isolation system parameters for the near-optimal design of structures
Authors: Leblouba Moussa 
Published: August 2022

AbstractThe benefits of seismic isolation are many. Structures that are isolated from the ground seismically perform better than those that are not. They experience reduced floor accelerations and drifts and are less likely to experience damage to structural elements. Additionally, their contents are better protected from the effects of earthquakes. The selection and design of seismic isolation devices are complex and require a good understanding of how they behave during earthquakes. This study investigates the effect of various isolation system parameters and ground motion characteristics on the seismic response of base isolated structures in order to develop rational procedures for design and analysis. Additionally, the study investigates the problem of optimal design of seismic isolation systems through parametric nonlinear dynamic analysis. Results showed that the maximum base shear and displacement were velocity-sensitive and that the peak ground velocity controls the motion. The largest maximum base shear occurred when using isolation systems with high yield strength levels and low degrees of nonlinearity, while the smallest maximum base shear occurred when using low yield strength levels and high degrees of nonlinearity. Results from the study can be used to select the appropriate isolation devices and design them correctly to achieve the benefits they provide.
The emerging pathogen Enterocytozoon hepatopenaei drives a degenerative cyclic pattern in the hepatopancreas microbiome of the shrimp (Penaeus vannamei)
Authors: López-Carvallo Jesús Antonio , Cruz-Flores Roberto , Dhar Arun K. 
Published: August 2022

AbstractThe microsporidian Enterocytozoon hepatopenaei (EHP) is an emerging pathogen that causes substantial economic losses in shrimp (Penaeus spp.) aquaculture worldwide. To prevent diseases in shrimp, the manipulation of the gut microbiota has been suggested. However, prior knowledge of the host-microbiome is necessary. We assessed the modulation of the microbiome (bacteria/fungi) and its predicted functions over the course of disease progression in shrimp experimentally challenged with EHP for 30 days using high throughput 16S rRNA and ITS amplicon sequencing. Infection grade was assessed for the first time by quantitative digital histopathology. According to the infection intensity, three disease-stages (early/developmental/late) were registered. During the early-stage, EHP was not consistently detected, and a high diversity of potentially beneficial microorganisms related to nutrient assimilation were found. In the development-stage, most of the shrimp start to register a high infection intensity related to a decrease in beneficial microorganisms and an increase in opportunistic/pathogenic fungi. During late-stage, animals displayed different infection intensities, showed a displacement of beneficial microorganisms by opportunistic/pathogenic bacteria and fungi related to pathogen infection processes and depletion of energetic reserves. The degenerative cyclic pattern of EHP infection and its effects on beneficial microorganisms and beneficial functions of the shrimp hepatopancreas microbiome are discussed.