bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of Carotid Body Tumors by Superb Microvascular Imaging of Feeding Arteries During Preoperative Evaluation
Authors: Gao Luying , Zhang Xiaoyan , Jiang Yuxin , Wang Hongyan , Zheng Yuehong , Li Wanying , Li Jianchu , Zhang Bo 
Published: September 2022

Purpose:Superb microvascular imaging (SMI) has led to new advances in vascular imaging applications. This study aimed to explore the blood supply and feeding arteries of carotid body tumors (CBTs) on SMI to improve the accuracy of information available to surgeons.MethodsTwenty-six CBT lesions were subjected to color Doppler flow imaging (CDFI) and SMI and were later confirmed by pathology. The blood flow patterns and feeding arteries of the CBTs on CDFI and SMI were graded and compared.ResultsThe feeding arteries of two CBT lesions, which were not visible on CDFI, were identified as the internal carotid artery (ICA) on SMI. The feeding arteries of three CBTs were judged to stem from both the ICA and the external carotid artery (ECA) (MIX) based on SMI compared to the ICA or ECA on CDFI. We classified the feeding arteries of CBTs as originating from the ICA or others (including the ECA and MIX). One hundred percent (3/3) of the CBT lesions stemming from the ICA had Adler I or Adler II blood flow patterns, and 100% (23/23) of the CBT lesions stemming from other arteries had Adler II or Adler III blood flow patterns. Higher Adler categories were assigned based on SMI than CDFI (P &lt; 0.001).ConclusionSMI may be superior to CDFI in detecting the vascularity of CBTs, and SMI revealed more potential feeding arteries of CBTs than CDFI. CBTs originating from the ICA are less vascular than those originating from the ECA.
CCDC25 may be a potential diagnostic and prognostic marker of hepatocellular carcinoma: Results from microarray analysis
Authors: Deng Hongyang , Zhang Jiaxing , Zheng Yijun , Li Jipin , Xiao Qi , Wei Fengxian , Han Wei , Xu Xiaodong , Zhang Youcheng 
Published: September 2022

BackgroundHepatocellular carcinoma (HCC) is a tumor with a high recurrence rate, poor prognosis, and rapid progression. Therefore, it is necessary to find a novel biomarker for HCC. Coiled-coil domain containing 25 (CCDC25) has been identified as a target molecule that mediates liver metastasis in colon cancer. However, the molecular mechanisms of CCDC25 in HCC are unknown. This study aimed to explore the role of CCDC25 in HCC.MethodsThe expression of CCDC25 in HCC was identified through The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) databases. Receiver operating characteristic curve (ROC) curves were drawn to evaluate the diagnostic value of CCDC25 for HCC. The effect of CCDC25 on the prognosis of HCC was analyzed by using the Kaplan–Meier plotter. Co-expressed genes and Gene Set Enrichment Analysis (GSEA) were used to explore the related functions and regulatory signaling pathways of CCDC25. Moreover, we employed the Tumor Immune Estimation Resource (TIMER) database and CIBERSORT algorithm to investigate the relationship between CCDC25 and the tumor immune microenvironment (TME) in HCC. Meanwhile, the effect of CCDC25 on the sensitivity of HCC patients to chemotherapy drugs was evaluated. Finally, we explored the prognostic methylation sites of CCDC25 using the MethSurv database.ResultsCCDC25 expression was low in HCC. Low CCDC25 expression was significantly associated with poor overall survival of HCC and may be comparable to the ability of AFP to diagnose HCC. Dysregulation of glucose metabolism, fatty acid metabolism, amino acid metabolism, ubiquitination modification, and apoptosis inhibition caused by CCDC25 downregulation may be the causes and results of HCC. In addition, CCDC25 was positively correlated with the infiltration level of various adaptive antitumor immune cells. The levels of immune cell infiltration and immune checkpoint expression were lower in the samples with high CCDC25 expression. What is more, we found that downregulated CCDC25 may increase the sensitivity or resistance of HCC patients to multiple drugs, including sorafenib. We also identified a methylation site for CCDC25, which may be responsible for poor prognosis and low CCDC25 expression in HCC patients. Finally, CCDC25 may be associated with HCC ferroptosis.ConclusionsCCDC25 may be a potential diagnostic and prognostic marker for HCC and is associated with immune infiltration and ferroptosis.
Prediction of factors influencing the timing and prognosis of early tracheostomy in patients with multiple rib fractures: A propensity score matching analysis
Authors: Zhang Bing , Li Gong-Ke , Wang Yu-Rong , Wu Fei , Shi Su-Qin , Hang Xin , Feng Qin-Ling , Li Yong , Wan Xian-Yao 
Published: September 2022

ObjectiveTo investigate the factors affecting the timing and prognosis of early tracheostomy in multiple rib fracture patients.MethodsA retrospective case-control study was used to analyze the clinical data of 222 patients with multiple rib fractures who underwent tracheotomy in the Affiliated Hospital of Yangzhou University from February 2015 to October 2021. According to the time from tracheal intubation to tracheostomy after admission, the patients were divided into two groups: the early tracheostomy group (within 7 days after tracheal intubation, ET) and late tracheostomy group (after the 7th day, LT). Propensity score matching (PSM) was used to eliminate the differences in baseline characteristics Logistic regression was used to predict the independent risk factors for early tracheostomy. Kaplan–Meier and Cox survival analyses were used to analyze the influencing factors of the 28-day survival.ResultsAccording to the propensity score matching analysis, a total of 174 patients were finally included in the study. Among them, there were 87 patients in the ET group and 87 patients in the LT group. After propensity score matching, Number of total rib fractures (NTRF) (P &lt; 0.001), Acute respiratory distress syndrome (ARDS) (P &lt; 0.001) and Volume of pulmonary contusion(VPC) (P &lt; 0.000) in the ET group were higher than those in the LT group. Univariate analysis showed that the patients who underwent ET had a higher survival rate than those who underwent LT (P = 0.021). Pearson's analysis showed that there was a significant correlation between NTRF and VPC (r = 0.369, P = 0.001). A receiver operating characteristic(ROC)curve analysis showed that the areas under the curves were 0.832 and 0.804. The best cutoff-value values of the VPC and NTRF were 23.9 and 8.5, respectively. The Cox survival analysis showed that the timing of tracheostomy (HR = 2.51 95% CI, 1.12–5.57, P = 0.004) and age (HR = 1.53 95% CI, 1.00–2.05, P = 0.042) of the patients had a significant impact on the 28-day survival of patients with multiple rib fractures. In addition, The Kaplan–Meier survival analysis showed that the 28-day survival of patients in the ET group was significantly better than that of the LT group, P = 0.01.ConclusionsNTRF, ADRS and VPC are independent risk factors for the timing and prognosis of early tracheotomy. A VPC ≥ 23.9% and/or an NTRF ≥ 8.5 could be used as predictors of ET in patients with multiple rib fractures. Predicting the timing of early tracheostomy also need prediction models in the future.
Why does patients’ discharge delay after vertebral augmentation? A factor analysis of 1,442 patients
Authors: Zhao He , Zhang Zhengping , Wang Yanjun , Qian Bing , Cao Xinhao , Yang Ming , Liu Yangjin , Zhao Qinpeng 
Published: September 2022

ObjectiveVertebral augmentation techniques are widely used to treat osteoporotic vertebral compression fractures (OVCFs). Superior analgesic effects and shortened bed rest time means patients recover quickly, but prolonged unscheduled hospitalization can increase medical expenses and the risk of bed rest complications. The aim of this study was to investigate the reasons for prolonged hospitalization after vertebral augmentation surgery and to determine the relative risk factors.MethodsA single-center retrospective study was conducted to enroll patients with OVCFs and accepted vertebral augmentation surgery from January 2017 to December 2017. Clinical information was collected from the Hospital Information System (HIS). The criterion of delayed discharge was postoperative hospitalization more than 3 days. Telephone interviews and medical history evaluations were conducted to confirm the exact reason for retention. The risk factors were analyzed by multiple logistic regression.ResultsOverall, 1,442 patients were included, and 191 (13.2%) stayed in the hospital for more than 3 days postoperatively. The reasons for delayed discharge were psychological factors (37.2%), residual pain (32.5%), cardiopulmonary complications (15.7%), nonspecific symptoms (8.4%), incision abnormalities (2.6%), thrombosis (2.1%), and postanesthesia reactions (1.6%). The multiple logistic model was significant; age (OR 1.028; 95% CI 1.009–1.046), preoperative stay (OR 1.192; 95% CI 1.095–1.298), operation type (OR 1.494; 95% CI 1.019–2.189), and the number of surgical segments (OR 2.238; 95% CI 1.512–3.312) showed statistical significance. In contrast, gender (P &gt; 0.1) and chronic comorbidities (P &gt; 0.1) were not predictors in this model.ConclusionOverall, 13.2% of OVCF patients who underwent vertebral augmentation surgery were not discharged within 3 days postoperatively, and several predictors were found. Preoperative communication and comprehensive evaluations are calling for more attention; physicians should adopt an appropriate medical process to enhance rehabilitation in geriatric orthopedics.
The Influence of Bargaining Relationships and the Development of Approaches to Employee Engagement and CSR
Authors: Hermanto Ahmad 
Published: September 2022

CSR is one of the drivers of employee engagement is a trend and the attention of researchers in the business world today. Experience proves that Employee engagement helps organizations to increase profits, commitment and loyalty reduces attrition, reduce absenteeism, and accidents which in turn adds up to the revenues of the firm. This study seeks to investigate whether the model of transactional, relational, and developmental approaches is an effective approach in applying the concept of CSR as a tool for employee engagement.<div id="essential_id_for_layout" style="position: fixed; width: 100%; height: 100%; top: 0px; left: 0px; bottom: 0px; right: 0px; display: none; background-color: rgba(0, 0, 0, 0.3); z-index: 9999999; cursor: pointer;"> </div>
Revitalizing MSMEs through Marketing Digitalization and Business Continuity Management (BCM) Toward MSMEs In Kota Medan, North Sumatera.
Authors: Hermanto Ahmad , Hasbullah, S.Ip., M.Sc. Amilia 
Published: September 2022

<p>Micro Small and Medium Enterprises (MSMEs) experienced enormous economic pressure during the COVID-19 outbreak. These conditions have a direct effect on their business performance, especially on the value of sales, products and services produced, thereby impacting the sustainability of their business. Since Medan known as one of biggest city in Indonesia, where the existence of MSMEs have the significance role to generate income within the community, therefore this paper is intended to analyze how MSMEs are able to rise and can continue their business activities through efforts to implement the concept of Business Continuity Management (BCM) and digital marketing. </p><div id="essential_id_for_layout" style="position: fixed; width: 100%; height: 100%; top: 0px; left: 0px; bottom: 0px; right: 0px; display: none; background-color: rgba(0, 0, 0, 0.3); z-index: 9999999; cursor: pointer;"> </div><div id="essential_id_for_layout" style="position: fixed; width: 100%; height: 100%; top: 0px; left: 0px; bottom: 0px; right: 0px; display: none; background-color: rgba(0, 0, 0, 0.3); z-index: 9999999; cursor: pointer;"> </div><div id="essential_id_for_layout" style="position: fixed; width: 100%; height: 100%; top: 0px; left: 0px; bottom: 0px; right: 0px; display: none; background-color: rgba(0, 0, 0, 0.3); z-index: 9999999; cursor: pointer;"> </div>
معايير الفصل في صحة العضوية البرلمانية وطبيعتها القانونية
Authors: محمود بشار , حنتوش ليلى 
Published: September 2022

تظهر مسألة الطعن في صحة العضوية النيابية لأسباب عديدة منها ، عدم مراعاة النصوص الدستورية او القانونية او اللائحة المنظمة للعملية الأنتخابية المتداخلة في اجراءاتها ومراحلها مثل عدم توافر شروط الترشيح التي نظمت من خلال القانون للسماح بالترشح للعضوية البرلمانية ، أو عيوب أصابت اجراءات العملية الانتخابية ادت الى عدم سلامتها ، مما يتطلب اختيار جهة مناسبة للفصل في صحة العضوية البرلمانية .
اتفق الفقهاء على مبدأ" ان الاختصاص بالنظر في الطعون والدعاوي لصحة العضوية البرلمانية يقوم على أساس تحديد طبيعة العمل في محل الطعن أو الدعوى" ، لكنهم أنقسموا الفقهاء في الرأي حول التركيز على طبيعة العمل للجهة المختصة في صحة العضوية البرلمانية من حيث الاجراءات في محل الطعن الى قسمين ، القسم الأول رأى ان طبيعة القرارات المتعلقة بالعملية الأنتخابية بكافة مراحلها بدءآ من عملية الترشيح الى اعلان نتيجة الأنتخابات النهائية بدون اي استثناء بأنها قرارات اداريه ، أما القسم الثاني من رأى ان العملية الانتخابية ما هي إلا عملية مركبة بين قرارات ادارية واعمال قانونية مختلفة.
Analysis and Characterization of an Unclassified RFI Affecting Ionospheric Amplitude Scintillation Index over the Mediterranean Area
Authors: Pica Emanuele , Minetto Alex , Cesaroni Claudio , Dovis Fabio 
Published: September 2022

<p>Radio Frequency (RF) signals transmitted by Global Navigation Satellite Systems (GNSS) are exploited as signals of opportunity in many scientific activities, ranging from sensing waterways and humidity of the terrain to the monitoring of the ionosphere. The latter can be pursued by processing the GNSS signals through dedicated ground-based monitoring equipment, such as the GNSS Ionospheric Scintillation and Total Electron Content Monitoring (GISTM) receivers. Nonetheless, GNSS signals are susceptible to intentional or unintentional RF interferences (RFIs), which may alter the calculation of the scintillation indices, thus compromising the quality of the scientific data and the reliability of the derived space weather monitoring products. Upon the observation of anomalous scintillation indices computed by a GISTM receiver in the Mediterranean area, the study presents the results of the analysis and characterization of a deliberate, unclassified interferer acting on the L1/E1 GNSS signal bands, observed and captured through an experimental, software defined radio setup. The paper also highlights the adverse impacts of the interferer on the amplitude scintillation indices employed in scientific investigations, and presents a methodology to discriminate among regular and corrupted scintillation data. To support further investigations, a dataset of baseband signals samples affected by the RFI is available at IEEE DataPort. </p>
USING TUNA MEAT AS A SUPPLEMENT TO INCREASE TESTOSTERONE HORMONE LEVEL IN MEN
Authors: Hasan Baqer J. , Abbas Zainab Fadhil 
Published: September 2022

This experiment was designed to investigate the effect of using tuna meat as a supplement to increase testosterone hormone level in men. The experiment based on 15 non married men aged (21 – 27) divided into two groups, group of ten men who ate 100 g of tuna daily for 15 days, the other group consists of 5 men were on a control diet . Testosterone levels of all men were examined before and after by blood tests using I-chroma test procedure. The results after 15 days showed significant variant in the T hormone. For example, the treated group results before eating tuna was ( 3.22 , 2.67 , 7.38 , 2.29 , 2.91 , 2.82 , 2.52 , 2.99 , 1 , 2.54 ) ng/ml and after eating tuna is ( 2.64 , 1.94 , 7.13 , 3.47 , 6.62 , 3.68 , 3.9 , 5.32 , 2.7 , 3.5 ) ng/ml respectively. While the control group were, before: ( 4.1 , 1.06 , 3.97 , 2.15 , 1.86 ) ng/ml and after: ( 1.5 , 2 , 2.3 , 3.34 ) ng/ml respectively. The percentage of hormonal variation before and after experiment in treated group were ( -18% , -27% , -3% ) decrease for samples no. ( 1, 2, 3 ) respectively and for samples no (4, 5, 6, 7, 8, 9, 10 ) were ( 51%, 127%, 30%, 54%, 77%, 170%, 37% ) increase. While the control group have decreased levels in samples no. ( 1, 3 ) with percentage of (-14%, -49% ) respectively, and increased levels in samples number ( 2, 4, 5 ) with percentage of ( 41%, 7%, 79% ). as we notice, not much difference in control group, but treatment group has certain increase in seven samples and decrease in only three samples, because of several factors that the samples was exhibited to leads to decrease the hormone in these samples after treatment. The study concluded that , continuous oral consumption of 100g as supplement of Tuna meat for at least 15 days can lead to increase and/or regulate blood levels of testosterone hormone in men.
PENGARUH EFEKTIFITAS PIJAT BAYI TERHADAP PENINGKATAN LAMANYA TIDUR MALAM PADA BAYI 0-3 BULAN
Authors: Siregar Riani Baiduri , Siregar Harryjun K 
Published: September 2022

Penelitian ini merupakan pre-eksperimental dengan menggunakan one group pretest – posttest design dengan tujuan untuk mengetahui secara langsung efek pemberian pijat bayi terhadap lamanya tidur bayi di malam haripada bayi usia 0-3 bulan pada saat sebelum perlakuan dengan sesudah perlakuan pada satu kelompok. Subjek penelitian sejumlah 10 orang bayi yang memenuhi kriteria inklusi.Pengujian Hipotesa dilakukan dengan menggunakan paired sample t test, Analisis ini digunakan untuk menguji dua kelompok data dependent dengan skala data interval atau rasio. Dengan ketentuan pengujian Hipotesa gagal ditolak bila p < α (0,05).Hasil uji Hipotesa dengan menggunakan paired sample t-test diperoleh nilai significant p = 0,003 dimana p < α (0,05), yang artinya ada efek pemberian pijat bayi terhadap peningkatan lama tidur malam hari pada bayi usia 0-3 bulan sebelum dan sesudah pemijatan.Dari hasil penelitian dapat diambil kesimpulan dari data tersebut bahwa ada efek pemberian pijat bayi terhadap peningkatan lama tidur malam hari pada bayi usia 0-3 bulan sesudah pemijatan.
Weighing the benefits of Karl Larenz
Authors: Nastasiichuk Oleksandr 
Published: September 2022

The article “Weighing the benefits of Karl Larenz” speaks about – in the terminology of the analytical philosopherW. Stegmüller – the direct interpretation and rational reconstruction of the idea of weighing the benefits in the legal methodology ofthe German professor K. Larenz (1903-1993). In the first case it is a description and statement of what the author mentioned in the titleof the article really had in mind when analyzing the weighing in law, and in the second about the implementation of the followingrequirements: the theory of weighing benefits should be presented in such a way that the presentation remains in agreement with themain ideas of K. Larenz; it should be set out to the extent possible with precise concepts, and also developed as a consistent (coherent)theory if possible.It was initially taken into account that the “legal career” of the concept of weighing in German (Federal German Republic)jurisprudence begins – according to H. Rückert – began in the middle of the last century, ie after 1950 and continues to the present.
This almost coincides with the beginning of the publication of K. Larenz’s “Methodology of Jurisprudence”, which took place in 1960.In six editions of “Methodology”, “weighing of benefits” appeared as a heading only in the third edition, which was published in 1975and did not leave it in the subsequent 4-6 editions (the sixth was published in 1991), although lapidary analysis of weighing as suchhas place in the first edition. In general, Larenz’s concept of weighing was built within the neo-Hegelian direction in philosophy togetherwith philosophical hermeneutics, ie not with the help of analytical (in the sense of analytical philosophy) method, and therefore necessarilyrequires a rational, or rather analytical reconstruction.Rational reconstruction is carried out on the basis of, firstly, such a precise concept as “semantic rules” (R. Carnap), which meansinterpretive (in a broad sense) provisions, which together with the provisions on the norm and the fact, play the role of justifying thelegal decision.Secondly, such a reconstruction was carried out on the basis of three approaches proposed by such authors as: R. Aleksi,H.-J. Koch, H. Rüßmann and H. Rückert, namely: a) on the basis of the formulation of a new (the approach of R. Alexi) or b) the developmentof an old norm (the approach of H.-J. Koch (and H. Rüßmann) and c) without the formulation norms (the approach of H. Rückert),which in the first and second cases would have, and in the third could be a large (normative) basis within the framework of the socalled“internal justification” of a legal decision in the terminology of R. Alexi or within the framework of called the “main scheme”H.-J. Koch (and H. Rüßmann).As a result, it is shown that K. Larenz’s understanding of weighing properly is reconstructed with the help of H. Rückert’sapproach, that is, without the judge creating a new one and without developing the old norm.
PERBEDAAN PEMBERIAN BAYAM HIJAU DAN TABLET FE TERHADAP KADAR HEMOGLOBIN PADA IBU HAMIL DENGAN ANEMIA
Authors: Handayani Tri Restu 
Published: September 2022

Latar Belakang: Anemia defisiensi besi merupakan salah satu gangguan yang paling sering terjadi terutama selama masa kehamilan. Menurut World Health Organization (WHO), 40% kematian di negara berkembang berkaitan dengan anemia dalam kehamilan. Pemerintah beserta tenaga medis memberikan tablet Fe pada ibu hamil sebagai upaya meningkatkan zat besi selama kehamilan. Salah satu alternatif lainnya dalam pemenuhan kebutuhan zat besi yaitu dengan mengkonsumsi bayam hijau. Kandungan zat besi pada bayam berperan untuk pembentukan haemoglobin. Tujuan: Diketahuinya perbedaan pemberian bayam hijau dan tablet Fe terhadap kadar hemoglobin pada ibu hamil dengan anemia. Metode: Desain penelitian yang digunakan yaitu eksperimen dengan pretest-posttest with control group design. Penelitian dilakukan di Puskesmas Nagaswidak pada Januari 2019. Subjek penelitian adalah ibu hamil trimester tiga dengan kadar Hb < 11 gr/dl. Sampel berjumlah 30 ibu hamil yang memenuhi kriteria inklusi. Pengambilan sampel menggunakan teknik total sampling. Data dianalisis menggunakan uji homogenitas dan Mann Whitney test. Hasil : Uji homogenitas terhadap karakteristik masing-masing kelompok yang meliputi usia, paritas, pekerjaan dan pendapatan, menunjukkan nilai p > 0.05. Hasil uji non parametrik Mann Whitney test diperoleh nilai p 0.004 (p< 0.05). Terdapat perbedaan yang signifikan antara kadar Hb kelompok eksperimen yang diberikan bayam hijau dan tablet Fe dengan kelompok kontrol yang diberikan tablet Fe. Saran: Ibu hamil sebaiknya memanfaatkan sayuran hijau yang tinggi zat besi seperti bayam untuk dikonsumsi sebagai upaya pemenuhan kebutuhan zat besi selama kehamilan. Kata Kunci: Anemia Kehamilan, Bayam Hijau, Tablet Fe
Kollaborative Montageprozesse mit Behavior Trees/Collaborative Assembly Processes using Behavior Trees
Authors: Trinh Minh , Petrovic Oliver , Brecher Christian , Behery Mohamed , Lakemeyer Gerhard 
Published: September 2022

Die kollaborative Montage vereint die Vorteile der manuellen Montage, wie Flexibilität und Fingerfertigkeit des Menschen, sowie der automatisierten Fertigung durch die Präzision und Effizienz des Roboters. Kleinen und mittleren Unternehmen fehlt oft die Expertise, um solche Prozesse – vor allem bei einer hohen Produktvarianz – zu planen und durchzuführen. Dieser Beitrag stellt ein Framework mit Behavior Trees vor, um das Problem unter Einhaltung der Sicherheitsstandards zu vereinfachen.

Collaborative assembly combines the advantages of manual assembly, e.g. flexibility and dexterity of the human, as well as of automated manufacturing using the precision and efficiency of robots. Small and medium-sized businesses often lack the expertise to plan and execute such processes, especially in case of high product variances. This paper introduces a framework using behavior trees in order to simplify the problem while complying with safety standards at the same time.