bluuebunny/crossref_metadata_2025_split huggingface dataset:
TCF7L2 rs7903146 C>T gene polymorphism is not associated with hypoglycemia in sulfonylurea-treated type 2 diabetic patients
Authors: Ragia Georgia , Katsika Evgenia , Ioannou Charalampia , Manolopoulos Vangelis G. 
Published: July 2022

Abstract

Objectives
Hypoglycemia is the most common adverse effect of sulfonylureas (SUs) and a major concern when using these drugs. Transcription factor 7-like 2 (TCF7L2) rs7903146 C>T polymorphism is an established and well characterized genetic marker of type 2 diabetes (T2DM) risk. The aim of the present study was to analyze the potential association of TCF7L2 rs7903146 C>T polymorphism with SU-induced hypoglycemia in a well characterized cohort of SU-treated patients previously genotyped for cytochrome P450 2C9 (CYP2C9) and P450 oxidoreductase (POR).

Methods
The study group consisted of 176 SU-treated T2DM patients of whom 92 had experienced at least one drug-associated hypoglycemic event. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used for TCF7L2 rs7903146 genotyping.

Results
TCF7L2 rs7903146 C>T genotype and allele frequency did not differ between cases and controls (p=0.745 and 0.671, respectively). In logistic regression analysis adjusted for other factors affecting hypoglycemia, including CYP2C9 and POR genotypes, TCF7L2 rs7903146 C>T polymorphism did not increase the risk of hypoglycemia (OR=1.238, 95% C.I.=0.750–2.044, p=0.405).

Conclusions
TCF7L2 rs7903146 C>T polymorphism is not associated with SU-induced hypoglycemia. Identifying additional gene polymorphisms associated with SU-induced hypoglycemia is crucial for improving T2DM patient therapy with SUs.
Jenseits von Affektivismus und Intellektualismus
Authors: Noller Jörg 
Published: July 2022

Abstract
In recent times, Kant’s theory of the moral feeling of respect has increasingly come to the centre of Kant research. His diverse and seemingly contradictory characterisations of this feeling in particular have led to continued controversial discussion. While a number of scholars try to understand the special role of respect in Kant by isolating this feeling from its conceptual context or solely referring to its role as moral motivation, I will concentrate on the systemic position of respect within the framework of Kant’s theory of the autonomy of reason. Furthermore, I will try to elucidate the different characterisations of respect given by Kant, referring not only to his ethics, but also to his general theory of transcendental idealism. Examining the special place of respect within Kant’s transcendental idealism, I will plead for a compatibilist reading of respect, according to which the “intellectualist” as well as the “affectivist” view both hold true. This is motivated by interpreting respect as a volitional structure featuring rational as well as emotional dimensions.
Negative Globalität der Angst
Authors: Frankenberg Günter 
Published: July 2022

Abstract
The article traces and analyses the negative globality of pandemic fears. It follows them through literary texts, psychological theories of individual and collective fears as well as legal documents. Rather than treating fears as law’s other, notably pandemic fears are included in the controversial discussion on how law protects (or should protect) peoples’ freedom in a pandemic. In closing, the article presents different forms of fear defence and fear denial such as conspiracy myths.
Wer muss draußen bleiben?
Authors: Jaster Romy , Keil Geert 
Published: July 2022

Abstract
The Special Focus on invitation policy at universities contains a target article by Romy Jaster and Geert Keil, five commentaries, and a response. The question under discussion is what disqualifies a person from being invited to speak at a university. On liberal, Millian approaches, the epistemic benefits of free speech preclude no-platforming policies. More restrictive approaches demand the exclusion of speakers who are considered racist or otherwise hostile against marginalized groups. Jaster and Keil take a virtue-based approach to invitation policy: A person is ineligible as a speaker if she exhibits specific intellectual vices that are detrimental to the pursuit of truth, the university’s raison d’être. The five critics raise various concerns. Birgit Recki deems the virtue-based approach too restrictive: It is prone to exclude some speakers who make intellectually stimulating contributions. Eva von Redecker and Daniel Loick deem the criterion too permissive: It allows for contributions that should have no place on campus. Dieter Schönecker and Maria-Sibylla Lotter object that the approach is silent on all recent actual cases of ‘cancelling’ at universities. In their response, Jaster and Keil address these concerns and clarify their position.
Characterization of dual-band circularly polarized mushroom-shaped monopole antenna with modified ground plane
Authors: Kumar Yatendra , Gangwar Ravi Kumar , Kanaujia Binod Kumar 
Published: July 2022

Abstract
In this manuscript, an antenna design configured for dual-band circularly polarized (DBCP) characteristics is presented. The proposed design is quite compact (0.63 λ
g × 0.63 λ
g × 0.04 λ
g) and comprises a mushroom-shaped monopole with a modified ground structure (MGS). In the proposed antenna structure, dual-band CP behavior is generated through a tunable side stub joined orthogonally with the feed patch and reshaping the wide square slot. The impedance bandwidth is measured as 2900 MHz ranging from 1.32 to 4.22 GHz in the lower frequency band (Band 1); however, 980 MHz from 4.78 to 5.76 GHz in the higher frequency band (Band 2). The 3-dB AR bandwidth is measured as 370 MHz (from 3.54 to 3.91 GHz)in the lower frequency band; whereas, it is measured as 650 MHz (from 5.07 to 5.72 GHz) in the higher frequency band. The measured gains spread from 2.5 to 8.3 dBi with a maximum gain of 8.3 dBi in the lower frequency band, whereas 4.8 to 7.05 dBi with a 7.05 dBi maximum gain in the higher frequency band, respectively. The cross-polar rejection is observed greater than 14 dB. Besides, 3-dB half-power beamwidths are seen as 86° & 84°, and 87° & 86° in the x-z and y-z planes for the lower and higher frequency bands, respectively.
Comprehensive Nuclear-Test-Ban Treaty: relevant radionuclides
Authors: Geer L.-E. De 
Published: July 2022

Abstract
With the first version of the IDC
IDC is the acronym for the International Data Centre, IMS for the International Monitoring System and CTBT for the Comprehensive Nuclear-Test-Ban Treaty.
software all known radionuclides, less the natural ones and one “naturalised” man-made one, caused a spectrum measured in the IMS* network to be characterised as interesting from a CTBT* point of view. But this is really not true for the majority of nuclides, so a change has been made to let only nuclides from a limited set of so called CTBT relevant nuclides have an impact on the characterization scheme. In the present paper the concept of CTBT relevance is analysed and a set of 96 relevant nuclides are defined. Out of these 51 are fission products and 41 are neutron activation products. There are also 4 nuclides which are residues from the nuclear fuel itself or added tracers.
Evaluation of the International Monitoring System and International Data Centre of the Comprehensive Nuclear-Test-Ban Treaty Organization
Authors: Denier P. , Toivonen H. 
Published: July 2022

AbstractEvaluation and quality assurance activities of the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO) are reviewed with special emphasis on radionuclide technologies. The CTBTO carries out detailed evaluation in all fields of technical verification of the Treaty. The goal is to provide States Signatories with confidence in the quality of data from the International Monitoring System and data products of the International Data Centre. The largest technical evaluation effort has been the quality assessment of the operational software. About 1.3 million lines of source code and scripts were checked. Software characteristics, such as maintainability, were assessed using automated tool-based techniques and improvements were suggested. Specific to radionuclide technologies, several methods have been developed to cope with the large amounts of spectra produced each day by 80 radionuclide monitoring stations around the world. Some of the key evaluation results, such as the peak detection capability of the operational software are presented in detail.
Kapitän zur See Hans Langsdorff – »the Captain who defied Hitler«?
Authors: Epkenhans Michael 
Published: July 2022

Zusammenfassung
Der Aufsatz zeichnet die Geschichte des Panzerschiffs »Admiral Graf Spee« und seines Kommandanten, Kapitän zur See Hans Langsdorff, nach. Einerseits geht es um die Entscheidung zur Selbstversenkung, andererseits aber auch um die Rezeption dieser Entscheidung und Langsdorffs Suizids. Zugleich untersucht der Artikel auch die Langsdorff-Rezeption nach 1945 im Ausland und in der Bundesrepublik. Warum wurde Langsdorff zu einem Mythos, und inwieweit ist es aufgrund bisher nicht berücksichtigter Quellen notwendig, diesen zu dekonstruieren?
Modules with fusion and implication based over distributive lattices: Representation and duality
Authors: Calomino Ismael , Zuluaga Botero William J. 
Published: July 2022

AbstractIn this paper, we study the class ofmodules with fusion and implication based over distributive lattices, orFIDL-modules, for short. We introduce the concepts of FIDL-subalgebra and FIDL-congruence as well as the notions of simple and subdirectly irreducible FIDL-modules. We give a bi-sorted Priestley-like duality for FIDL-modules and moreover, as an application of such a duality, we provide a topological bi-spaced description of the FIDL-congruences. This result will allows us to characterize the simple and subdirectly irreducible FIDL-modules.
Some exponential diophantine equations II: The equationx2–Dy2=kzfor evenk
Authors: Fujita Yasutsugu , Le Maohua 
Published: July 2022

AbstractLetDbe a nonsquare integer, and letkbe an integer with |k| ≥ 1 and gcd(D,k) = 1. In the partIof this paper, using some properties on the representation of integers by binary quadratic primitive forms with discriminant 4D, M.-H. Le gave a series of explicit formulas for the integer solutions (x,y,z) of the equationx2–Dy2=kz, gcd(x,y) = 1,z> 0 for 2 ∤kor |k| is a power of 2. In this part, we give similar results for the other cases ofk.
On concomitants of generalized order statistics from generalized FGM family under a general setting
Authors: Abd Elgawad Mohamed A. , Alawady Metwally A. 
Published: July 2022

AbstractIn this work, we study the distributional and moment properties of concomitants of dual generalized order statistics and consequently generalized order statistics. When the parameters are assumed to be pairwise different from Bairamov-Kotz-Becki Farlie-Gumbel-Morgenstern (BKB-FGM) family. Furthermore, an example of progressive type-II censored order statistics of BKB-FGM family under uniform distribution is obtained. Moreover, the joint distribution of dual generalized order statistics and record values of concomitants for this family are discussed. Finally, an application is given for some well-known distributions such as exponential, Pareto, and power function distributions.
First-principle calculation of electronic structure and optical properties of (P, Ga, P–Ga) doped graphene
Authors: Zhang Ying , Fu Yangchen , Mao Qingguo , Zhang Guohua , Zhang Wenchao , Wang Yi , Yang Wenlong 
Published: July 2022

Abstract
First-principle calculations are used to study the electronic structures, electronic and optical properties of pure, phosphorus-doped, aluminum-doped, and phosphorus and aluminum co-doped graphene. The gap between the conduction band and valence band of intrinsic graphene is zero. However, when graphene is doped with P, Ga, and P–Ga, the gap in energy will be opened and to a different extent. In the three different doping results, the gap values between the conduction and valence bands of P, Ga, and P–Ga graphene are 0.11, 0.35, and 0.39 eV, respectively. When graphene is doped with P–Ga, more electrons (1.40 e) will be gained by carbon atoms compared to P-doped graphene (0.61 e), while fewer electrons (1.49 e) will be transferred to carbon atoms compared to Ga-doped graphene (1.75 e). After doping with P, Ga, and P–Ga, the overall intensity of the graphene absorption peak is weakened and more pronounced relative to the low-frequency peaks. This result can fully demonstrate that the band gap of the doped graphene system can be better tuned by adding phosphorus and gallium atoms.
The properties of 3D printed poly (lactic acid) (PLA)/poly (butylene-adipate-terephthalate) (PBAT) blend and oil palm empty fruit bunch (EFB) reinforced PLA/PBAT composites used in fused deposition modelling (FDM) 3D printing
Authors: Ayob Nor Amira Izzati , Mohammad Rawi Nurul Fazita , Abd Aziz Azniwati , Azahari Baharin , Mohamad Kassim Mohamad Haafiz 
Published: July 2022

Abstract
Poly (lactic acid) (PLA) is amongst the preferable materials used in 3D printing (3DP), especially in fused deposition modelling (FDM) technique because of its unique properties such as good appearance, higher transparency, less toxicity, and low thermal expansion that help reduce the internal stresses caused during cooling. However, PLA is brittle and has low toughness and thermal resistance that affect its printability and restricts its industrial applications. Therefore, PLA was blended with various content of polybutylene adipate terephthalate (PBAT) at 20, 50 and 80 wt% via twin-screw extruder to improve the ductility and impact properties of PLA. The addition of PBAT increased the elongation at break of PLA with a linear increasing amount of PBAT. However, 20 wt% PBAT was selected as the most promising and balance properties of PLA/PBAT because although it has a slight increment in its elongation at break but it exhibits higher impact strength than that of PLA. The tensile strength and tensile modulus of sample with 20 wt% PBAT is greater than 50 and 80 wt% PBAT. Then, PLA/PBAT (80/20, 50/50 and 20/80) and PLA/PBAT/EFB (80/20/10) were printed using FDM machine and were characterized in tensile, impact and morphological properties. The tensile result indicated that the addition of PBAT decreased the tensile strength and tensile modulus of PLA/PBAT-3DP. The terephthalate group in the PBAT affects the mechanical properties of PLA/PBAT-3DP, resulting in high elongation at break but relatively low tensile strength. Besides, the tensile strength and tensile modulus of PLA/PBAT/EFB-3DP decreased and lower than PLA-3DP and PLA/PBAT-3DP. The impact test resulted in high impact strength in PLA/PBAT-3DP, where 50/50-3DP and 20/80-3DP are unbreakable. The impact strength of PLA/PBAT/EFB-3DP is also increased from PLA-3DP but lower than PLA/PBAT-3DP. The scanning electron microscopy (SEM) results revealed that the filament layering on 80/20-3DP was oriented than 50/50-3DP and 20/80-3DP. Besides, the SEM images of PLA/PBAT/EFB-3DP revealed the inhomogeneous and large agglomeration of EFB particle in PLA/PBAT matrix. Therefore, in the future, the polymer blend and polymer blend composite from PLA, PBAT and EFB can be developed where the properties will be based on the study and this study also shed light on the importance of extrusion settings during the manufacture of filament for 3D printing.
Clean energy consumption and economic growth in China: a time-varying analysis
Authors: Bahramian Pejman , Saliminezhad Andisheh , Fethi Sami 
Published: July 2022

Abstract
Assessing the causal relationships between clean energy consumption and economic growth in China, a central actor in the world’s climate future, have received considerable attention among scholars. However, due to the lack of methodological rigour in the causality analysis, available literature failed to provide solid inferences on the links between the variables. Therefore, this study aims to re-examine the variables’ dynamic linkages with a more well-established approach from 1965 to 2020. We use a time-varying framework that relaxes the assumption of parameter stability, a remarkable feature that distinguishes our paper from the previous studies. Utilizing the conventional Granger causality test, we fail to detect causation between the variables. However, the evidence of substantial time variation in the causal relationships implies that the standard framework’s inference is unreliable. The findings of our time-varying analysis indicate different forms of causality flows in various subperiods. This can be a dependable reason for China to follow its enhanced carbon neutrality target safely. The results of our study also emphasize the significance of considering time-varying causality tests to avoid the risk of misleading inferences.
EpCAM is critical for tumor proliferation and oxaliplatin chemoresistance in EpCAMhigh/CD44+ colorectal cancer stem cells
Authors: Qi Yanmei , Zhou Fengqiang , Geng Zhen , Ding Baozhong , Liu Lei 
Published: July 2022

Abstract

Objectives
A small subpopulation of colorectal cancer stem cells (CSCs) possess the ability to self-renew and the capacity to initiate the original tumor. EpCAMhigh/CD44+ cells are regarded as CSCs in colorectal cancer. The present study was undertaken to investigate the significance of EpCAM in the in vitro proliferation ability and oxaliplatin chemoresistance of EpCAMhigh/CD44+ colorectal CSCs.

Methods
We applied fluorescence-activated cell sorting (FACS) to separate the EpCAMhigh/CD44+ subset from human colorectal cancer cell line HCT116. We also used siRNA targeting EpCAM to create EpCAM−/CD44+ subpopulation. Then we compared EpCAMhigh/CD44+ cells and EpCAM−/CD44+ cells for proliferation ability and the chemoresistance to oxaliplatin by CCK8 assay.

Results
The EpCAMhigh/CD44+ subset comprises almost 6.25 ± 0.09% in cell line HCT116, and the EpCAM−/CD44+ cells displayed a significantly lower proliferation ability and weaker oxaliplatin chemoresistance than the EpCAMhigh/CD44+ cells.

Conclusions
EpCAM is critical for tumor proliferation and oxaliplatin chemoresistance in EpCAMhigh/CD44+ colorectal CSCs.
The Role of Strength on Punch Impact Force in Boxing
Authors: Beattie Kris , Ruddock Alan D. 
Published: July 2022

Abstract
Beattie, K and Ruddock, AD. The role of strength on punch impact force in boxing. J Strength Cond Res 36(10): 2957–2969, 2022—The ability to punch with a high impact force is beneficial to boxers as there is an increased likelihood of success. Punch impact force differentiates between performance level, weight class, gender, and punch type in competitive boxers. Although technique is likely to play a major role in punch impact force, the capabilities of the neuromuscular system may also be a limiting factor. This review examines the role of strength on punch impact force in amateur and professional boxers. The maximal strength qualities of the lower body, as well as explosive strength qualities of both the upper and lower body, are largely associated with punch impact force in elite amateur boxers. Specifically, elite amateur boxers who punch with “high” impact forces have greater levels of lower-body maximal strength and explosive strength when compared with elite amateurs who punch with “low” impact forces. However, the maximal strength capabilities of the upper body are not associated with punch impact force and does not differentiate between elite boxers who punch with “high” and “low” impact forces. Therefore, based off the present evidence, this review recommends that for boxers who aim to develop their punch impact force, it may be advantageous to emphasize both maximal and explosive strength development of the legs, with only an explosive strength focus in the upper body. However, it is important to highlight that, to date, there are a lack of experimental studies in both elite amateur and professional boxing. Furthermore, there is a dearth of research in female boxing. Future experimental studies are needed to infer causality regarding the role that strength training has on punch impact force in both elite amateur and professional boxers.
Influence of the Menstrual Cycle on Muscle Glycogen Repletion After Exhaustive Exercise in Eumenorrheic Women
Authors: Matsuda Tomoka , Takahashi Hideyuki , Nakamura Mariko , Ogata Hazuki , Kanno Moe , Ishikawa Akira , Sakamaki-Sunaga Mikako 
Published: July 2022

Abstract
Matsuda, T, Takahashi, H, Nakamura, M, Ogata, H, Kanno, M, Ishikawa, A, and Sakamaki-Sunaga, M. Influence of the menstrual cycle on muscle glycogen repletion after exhaustive exercise in eumenorrheic women. J Strength Cond Res 37(4): e273–e279, 2023—The purpose of this study was to investigate the effect of the menstrual cycle on muscle glycogen repletion postexercise. Eleven women with regular menstrual cycles (age: 20.2 ± 1.3 years, height: 161.1 ± 4.8 cm, and body mass: 55.5 ± 5.7 kg) were assessed in 3 phases of the cycle: the early follicular phase (E-FP), late follicular phase (L-FP), and luteal phase (LP). Each test day began with glycogen-depleting exercise, followed by 5 hours of recovery. Muscle glycogen concentrations, using 13C-magnetic resonance spectroscopy, and estradiol, progesterone, blood glucose, blood lactate, free fatty acid (FFA), and insulin concentrations were measured at t = 0, 120, and 300 minutes postexercise. During the 5-hour recovery period, subjects consumed 1.2g·(kg body mass)−1·h−1 of carbohydrates every 30 minutes. The muscle glycogen concentrations increased at t = 120 and t = 300 minutes postexercise (p < 0.01) but were not significantly different between the menstrual cycle phases (p = 0.30). Blood lactate concentrations were significantly higher in the L-FP and LP than in the E-FP (p < 0.05). Nonetheless, the blood glucose, FFA, insulin concentrations, and the exercise time until exhaustion in the E-FP, L-FP, and LP were similar (blood glucose, p = 0.17; FFA, p = 0.50; insulin, p = 0.31; exercise time, p = 0.67). In conclusion, the menstrual cycle did not influence muscle glycogen repletion after exercise.
Gender- and Sport-specific Normative Anthropometric and Physical Values in Talent-Identified High School Athletes
Authors: Larkin Paul , Sortino Benjamin , Carlon Todd , Saunders Trent , Pane Calvin 
Published: July 2022

Abstract
Larkin, P, Sortino, B, Carlon, T, Saunders, T, and Pane, C. Gender- and sport-specific normative anthropometric and physical values in talent-identified high school athletes. J Strength Cond Res 37(3): 606–615, 2023—Youth sport is associated with the identification and promotion of athletes within talent development pathways, with anthropometric and physical performance measures being key assessment and monitoring tools. To adequately evaluate performance within a population, normative reference data are needed; however, currently, there is limited normative values of talent-identified youth athletes. The aim of the current study is to present normative values of talent-identified youth sport academy athletes in relation to gender, age, and sport. Over a 5-year period, a total of 794 talent-identified youth athletes who attended a specialized school sports academy were assessed using anthropometric (i.e., heigh,; body mass) and physical performance (i.e., vertical jump, 20-m sprint, Yo-Yo intermittent recovery test 1) measures. In total, 451 male and 343 female athletes (grade 7: 12–13 years; grade 8: 13–14 years; grade 9: 14–15 years; grade 10: 15–16 years) were tested annually. The result demonstrates that for each gender, as age increases, there is a general increase in anthropometric measures (i.e., height and body mass). Furthermore, with increasing age, athletes generally have a higher vertical jump, faster sprint performance, and improved physical endurance. The results highlight sport-specific differences for each measure. Overall, the results of the study provides age-, gender-, and sport-specific normative data of talent-identified youth athletes. These findings provide representative performance profiles of talent-identified high school athletes, with the values potentially being used by coaching staff (i.e., head coaches, strength and conditioning coaches, rehabilitation staff) for comparison purposes.