bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of H2, H2O, and CO2 on the deNOx characteristics of a combined passive NOx adsorber and NOx reduction catalyst
Authors: Khatri Prateek , Bhatia Divesh 
Published: March 2022

AbstractThe effect of H2, H2O, and CO2 on the NOx removal characteristics of a non‐PGM material (Ag/MgO/γ‐Al2O3) is investigated, which is shown to be active for both NOx adsorption and reduction. H2O facilitates NOx adsorption at early times but inhibits it at longer times. The inhibiting effect of CO2 is observed at low temperatures and is proposed to be due to bicarbonates. However, the inhibiting effect of both H2O and CO2 decreases at higher temperatures. The formation of NO2 at low temperatures is attributed to NO oxidation, and the contribution of stored NOx to NO2 formation increases with temperature. H2O inhibits NH3 oxidation at high temperatures as well as NOx reduction by NH3‐SCR at low temperatures. However, the NOx reduction activity is not affected by CO2. H2 significantly promotes the NH3‐SCR reactions, which is attributed to the facilitation of NOx spillover from the reduced Ag sites to the support.
Strategies for monitoring mentoring relationship quality to predict early program dropout
Authors: Lyons Michael D. , Edwards Kelly D. 
Published: March 2022

AbstractWe examined data from a nationally implemented mentoring program over a 4‐year period, to identify demographic and relationship characteristics associated with premature termination. Data were drawn from a sample of 82,224 mentor and mentees. We found matches who reported shared racial or ethnic identities were associated with lower likelihood of premature termination as was mentee's positive feelings of the relationship. We also found that, if data were used as a screening tool, the data were suboptimal for accuracy classifying premature closure with sensitivity and specificity values equal to 0.43 and 0.75. As programs and policymakers consider ways to improve the impact of mentoring programs, these results suggest programs consider the types of data being collected to improve impact of care.
Re‐imagining mental health services for American Indian communities: Centering Indigenous perspectives
Authors: Gone Joseph P. 
Published: March 2022

AbstractThe Indigenous peoples of North America are heirs to the shattering legacy of European colonization. These brutal histories of land dispossession, military conquest, forced settlement, religious repression, and coercive assimilation have robbed American Indian communities of their economies, lifeways, and sources of meaning and significance in the world. The predictable consequence has been an epidemic of “mental health” problems such as demoralization, substance abuse, violence, and suicide within these communities. One apparent solution would seem to be the initiation or expansion of mental health services to better reach American Indian clients. And yet, conventional mental health services such as counseling and psychotherapy depend on assumptions and aspirations that may not fit well with American Indian cultural sensibilities. For example, counseling practices draw on the presumed value for clients of introspective and expressive “self talk,” whereas Indigenous community norms may emphasize communicative caution outside of interactions with intimate kin, leading to marked reticence rather than candid disclosure. Moreover, given community sensitivities to salient histories of colonization, such differences have the potential to further alienate American Indian community members from the very services and providers designated to help them. In this article, I review a postcolonial predicament that bedevils American Indian community mental health services and trace a program of research that has sought to harness American Indian cultural and spiritual traditions for reimagining helping services in a manner that truly centers Indigenous perspectives.
A Nepalese bipolar case amidst risk and protective factors during COVID‐19 pandemic
Authors: Shakya Dhana Ratna , Upadhaya Sandesh Raj 
Published: March 2022

AbstractBipolar disorder is a chronic and recurring psychiatric illness. Emphasis on enhancing key protective factors like social support systems and promoting this to minimize risk factors like non‐compliance is one of the key strategies tied to enhance overall psychological, intellectual, and emotional health for symptoms remission and relapse prevention even during adverse situations like the COVID‐19 crisis. We intend here to point out implication of the dynamics of the protective and risk factors for bipolar mood through a 23‐year patient from eastern Nepal, which is largely harmonious in its multi‐ethnic, multilingual and multicultural social composition. This attribute of social cohesiveness and compassion is evident in this case report. When disturbed and ill, neighbors from native semi‐urban Nepalese society did support even in the times of crisis of COVID‐19 pandemic. The support of other people including neighbors is a key factor for the short‐term and long‐term management of bipolar mood.
Flow Patterns of Multiple Axial‐Radial Impellers for Potential Use in Aerated Stirred Tanks
Authors: Posadas-Navarro David , Palacios Carlos , Blancas-Cabrera Abel , Trujillo-Roldán Mauricio A. , Salinas-Vázquez Martín , Ascanio Gabriel 
Published: March 2022

AbstractThe hydrodynamics of a stirred tank equipped with multiple hybrid impellers was experimentally characterized. They were coaxially placed to agitate a viscous Newtonian fluid under gassed conditions. Experiments were performed by using the particle image velocimetry technique, and flow fields were reported in terms of the velocity magnitude, vertical currents, turbulent intensity, and strain rates. For comparison purposes, impellers providing radial flow (Rushton turbines) and axial flow (pitched blade turbines) were also tested. The results showed that hybrid impellers provided a uniform flow distribution throughout the tank at moderate strain rates, which make them an attractive alternative for fermentation processes with shear‐sensitive cultures and viscous liquids.
Composite Correlated Molecular Orbital Theory Calculations of Ring Strain for Use in Predicting Polymerization Reactions
Authors: Confer Matthew P. , Qu Taoguang , Rupar Paul A. , Dixon David A. 
Published: March 2022

AbstractStrained ring systems play an important role in synthesis and can be characterized by the ring strain energy (RSE). The RSE of 3, 4, 5, and 6 membered saturated and unsaturated ring systems containing N, O, P, and S heteroatoms and H, F, SiMe3, and SO2Me substituents were calculated at the G3(MP2) composite correlated molecular orbital theory level using up to 5 models to predict the RSE. Generally, the RSE decreased as ring size increased with a substantial decrease from 4 to 5 membered rings. Replacement of a ring CH2 with P or S reduced the RSE, consistent with less angle strain. The RSE for unsaturated systems were generally greater than for saturated systems due to increased angle strain. No general trends were found with respect to substituent effects. The RSE values suggest that 3‐pyrroline and 2‐pyrroline and their derivatives may be able to support ring opening metathesis polymerization and warrant further study.
Comparison of ad libitum snack consumption and acquisition between adolescents living with food security and food insecurity: A stage 1 registered report
Authors: Stadterman Jill , Karvay Yvette G. , Feuerstahler Leah , Burke Natasha L. 
Published: March 2022

AbstractObjectiveApproximately 11% of the U.S. population experiences food insecurity (FI; insufficient access to healthy food due to financial constraints). FI is associated with detrimental health outcomes, including the development of eating disorders (EDs). However, additional studies are needed, particularly in adolescence when EDs are likely to emerge. The current study will utilize an experimental ad libitum snack paradigm to investigate snack consumption, acquisition (i.e., taking snacks home), and associated disordered eating behaviors among racially, ethnically, and financially diverse adolescents living with FI and food security (FS).MethodSixty‐four adolescents will be recruited and randomized into one of two conditions: prior knowledge condition (i.e., participants will know prior to snacking that they can take any remaining food home) and no prior knowledge condition (i.e., participants will not know ahead of time that they can take snacks home).ResultsWe expect youth with FI to show increased eating and acquisition behaviors compared to youth with FS across both conditions.DiscussionThis study, utilizing a novel experimental design, is an important step in understanding how FI impacts adolescent eating behaviors among youth from marginalized backgrounds, who have historically been excluded from research.
HP‐SPC algorithm with dynamic partially connected structure for mmWave MIMO systems
Authors: Du Ruiyan , Liu Huajing , Guan Zhiqing , Liu Fulai 
Published: March 2022

AbstractThis article proposes a low complexity hybrid precoding algorithm for the switch network‐based dynamic partially connected (SPC) structure, that is, named as HP‐SPC algorithm. First, via a new defined effective optimal precoding matrix, the analog switch precoding matrix optimization problem is transformed into a sparse representation problem. Thus, invoking that the key characteristic of only one nonzero entry in each row of the analog dynamic switch precoding matrix, the analog dynamic switch precoding matrix can be accurately and effectively solved. Second, the digital precoding matrix optimization problem is modeled as a dictionary update problem by the defined effective optimal precoding matrix and the combining matrix. Further, the digital precoding matrix is easily optimized based on the defined effective optimal precoding matrix, since the measurement vectors are sparsely represented by a single dictionary atom. Third, the analog phase shifter precoding matrix is given by the phase rotation method. Finally, the precoding matrices are alternant updated until convergence, a near optimal solution of the precoding matrix is obtained. Compared with the previous works, the proposed HP‐SPC algorithm provides better hybrid precoding performance, for examples: (1) it avoids complexity computation such as matrix inversion and singular value decomposition, so that it presents a low computational complexity; (2) it has a favorable property of convergence since a stable point can be reached with about 10 loop iterations. Based on the simulation results, the effectiveness of HP‐SPC algorithm is further demonstrated.
The curvilinear effect of perceived overqualification on constructive voice: The moderating role of leader consultation and the mediating role of work engagement
Authors: Duan Jinyun , Xia Ying , Xu Yue , Wu Chia‐Huei 
Published: March 2022

AbstractDrawing on the social cognitive theory of self‐regulation, we proposed a model considering an inverted U‐shaped relationship between perceived overqualification and constructive voice. We reasoned from the theory that this curvilinear effect would be moderated by leader consultation, which could intensify the upward curvilinear trend and neutralize the downward curvilinear trend, and be mediated by work engagement. We conducted two studies to test our model. In Study 1, based on a three‐wave time‐lagged sample of 293 employees and 120 supervisors, we found an inverted U‐shaped relationship between perceived overqualification and constructive voice, which was moderated by leader consultation. In Study 2, we examined the proposed mediated moderation model using a sample of 231 matched leader–subordinate dyads. We found that, at lower levels, perceived overqualification has a positive association with constructive voice, which is mediated by work engagement, especially at higher leader consultation. At higher levels, perceived overqualification has a negative association with work engagement and thus constructive voice, especially at lower levels of leader consultation. The implications of our research are discussed.
Light‐induced high‐efficient cellular production of immune functional extracellular vesicles
Authors: Ruan Shaobo , Erwin Nina , He Mei 
Published: March 2022

AbstractExtracellular vesicle (EV)‐based therapies and vaccines are emerging. However, employment at the scale for population‐based dose development is always a huge bottleneck. In order to overcome such a roadblock, we introduce a simple and straightforward approach for promoting cellular production of dendritic cell derived EVs (DEVs) by leveraging phototherapy based light induction. Under the optimization of light wavelengths, intensities, and exposure times, we achieved more than 13‐fold enhancement in DEV production rate, while maintaining good integral quality and immune function from produced EVs. The LED light at 365 nm is optimal to reliably trigger enhanced cellular production of EVs no matter cell line types. Our observation and other reported studies support longer near UV wavelength does not impair cell growth. We conducted a series of investigations in terms of size, zeta potential, morphology, immune surface markers and cytokines, biocompatibility, cellular uptake behaviour, and immune‐modulation ability on eliciting cellular responses in vitro. We also validated the biodistribution, immunogenicity, and administration safety using light‐promoted DEVs in mice models from both male and female genders. Overall data supports that light promoted DEVs are highly immune functional with great biocompatibility for serving as good therapeutic platforms. The in vivo animal study also demonstrated light‐promoted DEVs are as well tolerated as native DEVs, with no safety concerns. Taken together, the data supports that light promoted DEVs are in excellent quality, high biocompatibility, in vivo tolerant, and viable for serving as an ideal therapeutic platform in scalable production.
Staphylococcus aureus nasal colonization increases the risk of cedar pollinosis
Authors: Morizane Atsushi , Uehara Yoshio , Kitamura Satoko , Komori Masahiro , Matsushita Masahide , Takeuchi Seisho , Seo Hiromi 
Published: March 2022

AbstractBackgroundOne‐third of the people in Japan are colonized with Staphylococcus aureus (S. aureus) and suffer from virulence factor‐mediated subclinical inflammation of the nares. We investigated whether subclinical inflammation contributed to cedar pollinosis affecting 20 million people annually.MethodsThe study participants were 814 inhabitants of the A or B prefectures. We compared the colonization rate and population structure of S. aureus, in association with the prevalence of cedar pollinosis, between participants in these two areas.ResultsA prefecture had twice the annual amount of airborne cedar pollen compared with B. The prevalence of cedar pollinosis was significantly higher in A (23.5%) than in B (13.1%) (p = 0.0004). Moreover, the prevalence of cedar pollinosis was higher in female participants (23.3%) than in male participants (14.7%) (p = 0.003). In addition, the prevalence of cedar pollinosis was higher in S. aureus carriers (24.2%) than in S. aureus noncarriers (17.9%) (p = 0.03). The isolation rate of clonal complex (CC) 508 was higher in the A group (21%) than in the B group (7%) (p = 0.015).ConclusionNasal colonization of S. aureus is a major risk factor for cedar pollinosis. However, the direct mechanism of this risk is currently unknown.
No human respiratory syncytial virus but SARS‐CoV‐2 found in children under 5 years old referred to Children Medical Center in 2021, Tehran, Iran
Authors: Letafati Arash , Aghamirmohammadali Fahimeh Sadat , Rahimi‐Foroushani Abbas , Hasani Seyed Abbas , Mokhtari‐Azad Talat , Yavarian Jila 
Published: March 2022

AbstractAcute respiratory infections (ARIs) are one of the leading causes of illness and death among community members worldwide. Viral infections are the most common agents estimated to be involved in these patients. This study aimed to investigate the prevalence of human respiratory syncytial virus (hRSV) and severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) among children with ARIs. This study evaluated the presence of SARS‐CoV‐2 and hRSV in 168 throat and nasopharyngeal swab samples using real‐time RT‐PCR. All samples were collected from children under 5 years old with ARIs who attended Children's Medical Center, Tehran, Iran, and sent to the Iranian National Influenza Center with appropriate conditions in 2021. Chi‐square and Fisher's exact tests were used for comparison of the data of the prevalence of hRSV and SARS‐CoV‐2 infections among children. Of 168 patients examined, 95 (57%) were male and 73 (43%) female. Out of them, 47 (28%) cases were younger than 1 year old and 121 cases (72%) were 1–5 years old. The most common clinical manifestations of patients were cough (78%), nausea (31%), diarrhea (27%), and fever (18%). Among 168 patients, no hRSV was detected, while the SARS‐CoV‐2 genome was identified in 16 (9.5%) patients. Among 16 positive cases of SARS‐CoV‐2, 8 (50%) were under 1 year old and 8 positive cases were 1–5 years old. This study was performed at cold months of the year but due to the coronavirus disease 2019 pandemic and adherence to health protocols, school closures, and virtual classes, no cases of hRSV infections were identified.
Effects of different carbon sources on metabolic profiles of carbohydrates in Streptococcus thermophilus during fermentation
Authors: Song Xin , Hou Chengjie , Yang Yong , Ai Liangzhong , Xia Yongjun , Wang Guangqiang , Yi Huaxi , Xiong Zhiqiang 
Published: March 2022

AbstractBACKGROUNDStreptococcus thermophilus is a major starter used in the dairy industry and it could improve the flavor of fermented products. It is necessary to improve biomass of S. thermophilus for its application and industrialization. The utilization of carbon sources directly affects the biomass of S. thermophilus. Therefore, the carbohydrate metabolism of S. thermophilus should be investigated.RESULTSIn the present study, metabolic parameters and gene expression of S. thermophilus S‐3 with different carbon sources were investigated. The physicochemical results showed that S. thermophilus S‐3 had high lactose utilization. Transcriptome analysis found that approximately 104 genes were annotated onto 15 carbohydrate metabolic pathways, of which 15 unigenes were involved in the phosphotransferase system and 75 were involved in the ATP‐binding cassette transporter system. In addition, 171 differentially expressed genes related to carbohydrate metabolism were identified. Expression of the galactose metabolism genes lacSZ and galKTEM increased significantly from the lag phase to the mid‐exponential growth phase as a result of the global regulator protein, catabolite control protein A (CcpA). The high expression of galK in the mid‐ to late‐ phases indicated that the metabolite galactose is re‐transported for intracellular utilization. CcpA regulation may also induce high expressions of glycolytic pathway regulated‐genes related to lactose utilization, including ldh, fba, eno, pfkA, bglA, pgi, pgm and pyk, producing optimal glycolytic flux and S. thermophilus S‐3 growth.CONCLUSIONThe present study provides new insights into the carbon metabolism regulation and provide theoretical support for high‐density fermentation of S. thermophilus S‐3. © 2022 Society of Chemical Industry.
Unternehmen: Wege in die Zukunft
Authors: Ehrensberger Christian 
Published: March 2022

AbstractIn der Chemie‐ und Pharmaindustrie sind die Ausgaben für Forschung und Entwicklung im Jahr 2020 gesunken. Gleichzeitig zeigt sich langfristig ein Abwärtstrend bei der Forschungsproduktivität in Unternehmen, also dem Verhältnis von Output zu investierten Mitteln. Dem lässt sich entgegenwirken.
Synthese im Blickpunkt: Organische Elektronik flexibler und weicher machen
Authors: Lissel Franziska 
Published: March 2022

AbstractDie organische Elektronik findet sich in Anwendungen von Flachbildschirmen bis zu Solarzellen. Kohlenstoffbasierte Materialien sind zwar weniger leistungsstark als klassische siliciumbasierte Elektronik, aber durch entsprechende Polymere lassen sich dehnbare Bauteile herstellen und so an die menschliche Haut anpassen. Eine Übersicht über Materialien und Eigenschaften der genutzten Polymere.
Effect of freeze–thaw cycles on the performance of cast‐in‐place piles in permafrost regions: Working state and action effect sharing
Authors: Shi Rui , Wen Zhi , Li Desheng , Gao Qiang , Wei Yanjing 
Published: March 2022

AbstractOwing to a minor thermal disturbance to the permafrost environment, cast‐in‐place piles are widely used for building and bridge foundations in permafrost regions. However, because of the dynamic and cyclic variation in frozen ground affected by the atmosphere, the load transfer mechanism is not yet clear, and the current design is economically insufficient. To illustrate the bearing pattern of cast‐in‐place piles subjected to freeze–thaw cycles, a systematic in situ investigation was carried out. Results show that the load from the superstructure has a marginal action effect, while freeze–thaw cycles have a more significant action effect. Freeze–thaw cycles have a decisive effect on the dynamic variations of the pile's working state and action effect sharing while the mechanisms are quite different, which vary with depths. Action effect sharing of the pile shaft and tip experiences a cyclic variation and is affected by the long‐term effect of freeze–thaw cycles. The shaft takes an increasing sharing proportion gradually and has a 19% rise after two freeze–thaw cycles, while the pile tip goes the opposite way. Two years after the building is completed, the bearing capacity is almost entirely provided by shaft resistance and mainly by the upper one‐third of the pile. This research clarifies several essential issues about the bearing pattern and provides solid scientific support and novel opinions for the pile design in permafrost regions.
Myricetin reverses epithelial–endothelial transition and inhibits vasculogenic mimicry and angiogenesis of hepatocellular carcinoma by directly targeting PAR1
Authors: Wang Ming , Ren Shanfa , Bi Zhun , Zhang Liang , Cui Mengqi , Sun Ronghao , Bao Jiali , Gao Dandi , Yang Bo , Li Xiaoping , Li Mingjiang , Xiao Ting , Zhou Hong‐gang , Yang Cheng 
Published: March 2022

AbstractMost antiangiogenic inhibitors targeting endothelium‐dependent vessels cannot inhibit tumor growth but promote tumor invasion and metastasis in some patients. Vasculogenic mimicry (VM) employs mechanisms that differ from those used to construct endothelium‐dependent vessels. Inhibiting VM may be a novel antiangiogenic strategy against alternative tumor vascularization. In this paper, myricetin was selected from among several flavonoid compounds as an effective PAR1 antagonist. In two different hepatocellular carcinoma (HCC) cell lines high‐expressed PAR1, myricetin inhibited cell migration, invasion and VM formation and reversed the expression of epithelial–endothelial transition (EET) markers by inhibiting PAR1 activation. Knockout of PAR1 inhibited HCC cell invasion and metastasis and weakened the inhibitory effect of myricetin on HCC cells. The migration, invasion and tube formation ability of PLC‐PRF‐5 cells were enhanced after PAR1 overexpression, and the inhibitory effect of myricetin was enhanced. A docking assay revealed that myricetin binds to Leu258 and Thr261 in the PAR1 activity pocket. Mutation of Leu258 and Thr261 inhibited the antitumor effect of myricetin in vitro and in vivo. In summary, myricetin reverses PAR1‐mediated EET and inhibits HCC cell invasion, metastasis, VM formation and angiogenesis by targeting PAR1, and Leu258 and Thr261 of PAR1 participate in VM and angiogenesis in HCC tissues.