bluuebunny/crossref_metadata_2025_split huggingface dataset:
Three short postmeal walks as an alternate therapy to continuous walking for women with gestational diabetes
Authors: Christie Hannah E. , Chang Courtney R. , Jardine Isabelle R. , Francois Monique E. 
Published: August 2022

The purpose of this study was to determine whether postmeal walking (PMW, breaking up exercise into short bouts after meals) is an effective and feasible alternative to continuous walking for the management of gestational diabetes. Forty-one women with gestational diabetes were randomised between weeks 28–30 gestation to either standard care (30 minutes continuous exercise) or standard care with PMW (10 minutes of walking after breakfast, lunch, and dinner). Continuous glucose and activity monitors were worn to measure glycaemic control and adherence during 3 days of standard care (baseline) followed by 3 days of postmeal or continuous walking. A linear mixed model analysed the changes from baseline between postmeal and continuous walking, as an average of the 3-day periods. Thirty-two women (PMW n = 17: control n = 15, 33 ± 5 years, body mass index 25 ± 4 kg·m–2) completed the trial. Postprandial and overnight glucose concentrations were similar between PMW and control; both interventions improved from baseline. There was no difference in adherence between groups; however, PMW completed more minutes of prescribed physical activity across baseline and intervention days compared to the continuous walking standard-care group. Preliminary findings from this proof-of-concept study suggest PMW could be a promising alternative to, and work interchangeably with, traditional advice to perform continuous moderate-intensity physical activity in women with gestational diabetes. Novelty: Three 10-minute postmeal walks may be comparable to 30 minutes continuous walking for glucose control in women with gestational diabetes. Accumulating activity in short bouts after meals is a feasible alternate to continuous exercise for women with gestational diabetes.
Mortality Patterns of Synchronous Uterine and Ovarian Cancers: A SEER Registry Analysis
Authors: Dood Robert Lee , Pappas Lisa M. , Collin Lindsay J. , Vranes Chelsey , Trabert Britton , Doherty Jennifer Anne 
Published: August 2022

Abstract

Background:
The degree to which uterine cancer metastatic to the ovary is misdiagnosed as synchronous stage I uterine and ovarian cancers is unclear. We sought to determine whether patients with synchronous cancers had mortality patterns similar to either stage IIIA uterine, stage I uterine, or stage I ovarian cancers alone.

Methods:
The Surveillance, Epidemiology, and End Results database was used to compare mortality of patients with synchronous stage I uterine and stage I ovarian cancers versus those with stage IIIA uterine, stage I uterine, or stage I ovarian cancers alone. We calculated age-adjusted mortality hazard ratios (HR) and 95% confidence intervals (CI) accounting for calendar year and grade, adjuvant treatment, grade 1 endometrioid cancers, grade 3 endometrioid cancers, and stage IA cancers.

Results:
Among the 9,321 patients, we observed lower age-adjusted mortality in patients with stage I synchronous cancers (n = 937) compared to those with stage IIIA uterine (n = 531; HR, 0.45 95% CI, 0.35–0.58), stage I uterine (n = 6,919; HR, 0.74; 95% CI, 0.60–0.91), and stage I ovarian cancers (n = 934; HR, 0.52; 95% CI, 0.41–0.67). Results were similar after taking into account diagnosis year and grade, and limiting to those receiving adjuvant therapy, grade 1 or grade 3 endometrioid cancers, or stage IA cancers.

Conclusions:
We observed lower mortality for synchronous stage I uterine and ovarian cancers, which was not explained by younger age, earlier stage, lower grade, histology type, or adjuvant therapy.

Impact:
The possible misdiagnosis associated with clinicopathologic of synchronous uterine and ovarian cancers does not appear to worsen survival on a population level.
Gamifying education for classroom engagement in primary schools
Authors: Mee Rita Wong Mee , Rao Yugeshineey Subba , Pek Lim Seong , Ghani Khatipah Abd , Von Wong Yee , Ismail Md Rosli , Shahdan Tengku Shahrom Tengku 
Published: August 2022

<span lang="EN-US">Gamification carries the element of fun and creativity into classroom teaching. It is not an unusual fact that playing games varied among learners and created an effective classroom environment. In the 21st-century teaching era, learners’ fun and creative learning environment are prioritized. Lessons filled with fun games are believed to produce a positive outcome during a lesson. Therefore, gamification prepares learners to be active and take responsibility for their learning. This study aimed to explore learners’ comprehension of the term ‘gamification’ and the effects of gamified elements implemented in the lesson on the targeted learners. A set of questionnaires was administered through an online survey to 100 respondents from local primary schools around Selangor who took part in a service-learning programmed. The data was then analyzed and presented in the form of tables. Results showed that respondents had prior knowledge of the term ‘gamification’ and the game culture’s overall context. The respondents agreed that their respective teachers had implemented several game elements when conducting a gamified lesson. Results also indicated that respondents were in preference to learn using gamified learning activities that helped them learn subconsciously. </span>
Feminismos e vivências: uma análise das relações de gênero na China continental
Authors: Gonçalves Tuane Oliveira 
Published: August 2022

A partir, principalmente, das ideias de Ya-chen Chen, o propósito deste artigo é trazer a debate o feminismo chinês e seu histórico de relevância nas pautas feministas e de gênero. Com o intuito de compreender como se consolidou o feminismo e quando começaram as discussões em torno do gênero na China continental, a análise vai desde um pouco antes da ascensão do Partido Comunista até problemas atuais. A ideia não é esgotar toda a discussão sobre o tema, mas introduzir a complexidade em torno das questões de gênero que estreitam as relações sociais no país asiático.
Lexicase Selection for Multi-Task Evolutionary Robotics
Authors: Stanton Adam , Moore Jared M. 
Published: August 2022

AbstractIn Evolutionary Robotics, Lexicase selection has proven effective when a single task is broken down into many individual parameterizations. Evolved individuals have generalized across unique configurations of an overarching task. Here, we investigate the ability of Lexicase selection to generalize across multiple tasks, with each task again broken down into many instances. There are three objectives: to determine the feasibility of introducing additional tasks to the existing platform; to investigate any consequential effects of introducing these additional tasks during evolutionary adaptation; and to explore whether the schedule of presentation of the additional tasks over evolutionary time affects the final outcome. To address these aims we use a quadruped animat controlled by a feed-forward neural network with joint-angle, bearing-to-target, and spontaneous sinusoidal inputs. Weights in this network are trained using evolution with Lexicase-based parent selection. Simultaneous adaptation in a wall crossing task (labelled wall-cross) is explored when one of two different alternative tasks is also present: turn-and-seek or cargo-carry. Each task is parameterized into 100 distinct variants, and these variants are used as environments for evaluation and selection with Lexicase. We use performance in a single-task wall-cross environment as a baseline against which to examine the multi-task configurations. In addition, the objective sampling strategy (the manner in which tasks are presented over evolutionary time) is varied, and so data for treatments implementing uniform sampling, even sampling, or degrees of generational sampling are also presented. The Lexicase mechanism successfully integrates evolution of both turn-and-seek and cargo-carry with wall-cross, though there is a performance penalty compared to single task evolution. The size of the penalty depends on the similarity of the tasks. Complementary tasks (wallcross/turn-and-seek) show better performance than antagonistic tasks (wall-cross/cargo-carry). In complementary tasks performance is not affected by the sampling strategy. Where tasks are antagonistic, uniform and even sampling strategies yield significantly better performance than generational sampling. In all cases the generational sampling requires more evaluations and consequently more computational resources. The results indicate that Lexicase is a viable mechanism for multitask evolution of animat neurocontrollers, though the degree of interference between tasks is a key consideration. The results also support the conclusion that the naive, uniform random sampling strategy is the best choice when considering final task performance, simplicity of implementation, and computational efficiency.
Intrinsic Evolution of Analog Circuits Using Field Programmable Gate Arrays
Authors: Whitley Derek , Yoder Jason , Carpenter Nicklas 
Published: August 2022

AbstractEvolvable hardware is a field of study exploring the application of evolutionary algorithms to hardware systems during design, operation, or both. The work presented here focuses on the use of field programmable gate arrays (FPGAs), a type of dynamically reconfigurable hardware device typically used for electronic prototyping in conjunction with a newly created open-source platform for performing intrinsic analog evolvable hardware experiments. This work targets the reproduction of seminal field experiments that generated complex analog dynamics of unclocked FPGAs evolved through genetic manipulation of their binary circuit representation: the bitstream. Further, it demonstrates the intrinsic evolution of two nontrivial analog circuits with intriguing properties, amplitude maximization and pulse oscillation, as well as the robustness of evolved circuits to temperature variation and across-chip circuit translation.
Nonhuman Cinema and the Logistical Sublime
Authors: Stine Kyle 
Published: August 2022

Abstract
Erika Magnusson and Daniel Andersson's Logistics (2012) is the longest film ever made, at over thirty-five days in duration. The film endeavors to make the world-spanning network of global logistics perceptible through an experience of the slow journey of the Dutch container-ship Elly Maersk from Gothenburg, Sweden, to Shenzhen, China. Following this document of an oceanic passage that coincided with—and was at one point halted by—the events of the Arab Spring, this article explores how extreme durational cinema raises questions about the position of the spectator and the limits of representation in an era of digitally networked media. It suggests that there exists, beyond the immediate relationship between spectator and image, a correspondence between the magnitude of filmic address and the logistical conditions of art's creation.
Appropriate dosing of sugammadex for reversal of rocuronium-/vecuronium-induced muscle relaxation in morbidly obese patients: a meta-analysis of randomized controlled trials
Authors: Liao Jian-Qiang , Shih Darrell , Lin Tzu-Yu , Lee Meng , Lu Cheng-Wei 
Published: August 2022

Objective To conduct a meta-analysis to compare different dosing scalars of sugammadex in a morbidly obese population for reversal of neuromuscular blockade (NMB). Methods PubMed®, ClinicalTrials.gov, Cochrane Central Register of Controlled Trials (CENTRAL) and Google Scholar were searched for relevant randomized controlled trials (RCTs) comparing lower-dose sugammadex using ideal body weight (IBW) or corrected body weight (CBW) as dosing scalars with standard-dose sugammadex based on total body weight (TBW) among morbidly obese people after NMB. Mean difference with SD was used to estimate the results. Results The analysis included five RCT with a total of 444 morbidly obese patients. The reversal time was significantly longer in patients receiving sugammadex with dosing scalar based on IBW than in patients receiving sugammadex with dosing scalar based on TBW (mean difference 55.77 s, 95% confidence interval [CI] 32.01, 79.53 s), but it was not significantly different between patients receiving sugammadex with dosing scalars based on CBW versus TBW (mean difference 2.28 s, 95% CI –10.34, 14.89 s). Conclusion Compared with standard-dose sugammadex based on TBW, lower-dose sugammadex based on IBW had 56 s longer reversal time whereas lower-dose sugammadex based on CBW had a comparable reversal time.
Circulating free triiodothyronine concentration is positively associated with β-cell function in euthyroid patients with obesity and type 2 diabetes
Authors: Gong Lei , Ma Aixia , Yin Xiaofei , Liang Kai , Liu Jinbo 
Published: August 2022

Objective To investigate the relationship between thyroid hormone concentrations and β-cell function in euthyroid patients with obesity and type 2 diabetes. Methods We performed a single-center cross-sectional study of 254 patients with type 2 diabetes mellitus aged ≥40 years. The participants were allocated to an obesity group or non-obesity group on the basis of their body mass index (BMI). Their β-cell function was assessed by measuring C-peptide concentration during a 75-g oral glucose tolerance test (OGTT); and their serum free triiodothyronine (FT3), free thyroxine (FT4) and thyroid-stimulating hormone concentrations were measured. Results The serum FT3 concentration and the C-peptide concentrations at five time points of the OGTT were significantly higher in the obesity group than in the non-obesity group. FT3 was positively associated with the β-cell function of the obesity group, but not that of the non-obesity group, in multiple linear regression analysis, after adjustment for potential confounding factors. Serum FT3 concentration was also significantly associated with indices of obesity (BMI, waist circumference, body fat percentage, fat mass, fat mass/height 2 and visceral fat area). Conclusions Obesity-associated high serum FT3 concentrations might affect β-cell function in euthyroid patients with obesity and type 2 diabetes.
Infection profile and risk factors for mortality in patients with end-stage renal disease attributable to systemic lupus erythematosus: a two-center integrated study
Authors: Chen Yuqiang , Zhang Lisha , Xue Qin , Wang Niansong 
Published: August 2022

Objective Renal impairment is a significant complication of systemic lupus erythematosus (SLE). Additionally, infection in patients with end-stage renal disease (ESRD) attributable to SLE is common, and it increases the risk of mortality. This study explored the infection profile and risk factors for mortality in patients with ESRD attributable to SLE. Methods In this retrospective, observational study of 125 hospitalized patients, demographic, clinical, laboratory, treatment, and prognosis data were retrieved and analyzed. Results The 125 cases included 98 pulmonary infections (78.4%), 14 urinary infections (11.2%), and 13 intestinal infections (10.4%). Twenty-six patients died within 1 month after enrollment. Univariate Cox regression and Kaplan–Meier analyses revealed several possible indicators potentially influencing patient survival. Furthermore, multivariate Cox regression analysis identified a higher SLE Disease Activity Index-2000 score, recent higher-dose glucocorticoid use, hypertension, and catheter indwelling as risk factors for higher mortality. Conclusions Infections were common in patients with advanced SLE and ESRD, and several risk factors might increase the risk of mortality. Once infection is identified, empiric antibiotics should be initiated immediately, and subsequent antibiotics should be applied per the results of drug sensitivity testing to clear the infection.
Characterization of Migratory Cells From Bioengineered Bovine Cartilage in a 3D Co-culture Model
Authors: Wu Ming Jia Michael , Sermer Corey , Kandel Rita A. , Theodoropoulos John S. 
Published: August 2022

Background: Chondrocyte migration in native cartilage is limited and has been implicated as one of the reasons for the poor integration of native implants. Through use of an in vitro integration model, it has previously been shown that cells from bioengineered cartilage can migrate into the native host cartilage during integration. Platelet-rich plasma (PRP) treatment further enhanced integration of bioengineered cartilage to native cartilage in vitro. However, it is not known how PRP treatment of the bioengineered construct promotes this. Hypothesis: PRP supports cell migration from bioengineered cartilage and these migratory cells have the ability to accumulate cartilage-like matrix. Study Design: Controlled laboratory study. Methods: Osteochondral-like constructs were generated by culturing primary bovine chondrocytes on the top surface of a porous bone substitute biomaterial composed of calcium polyphosphate. After 1 week in culture, the constructs were submerged in PRP and placed adjacent, but 2 mm distant, to a native bovine osteochondral plug in a co-culture model for 2 weeks. Cell migration was monitored using phase-contrast imaging. Cell phenotype was determined by evaluating the gene expression of matrix metalloprotease 13 (MMP-13), Ki67, and cartilage matrix molecules using quantitative polymerase chain reaction. When tissue formed, it was assessed by histology, immunohistochemistry, and quantification of matrix content. Results: PRP treatment resulted in the formation of a fiber network connecting the bioengineered cartilage and native osteochondral plug. Cells from both the bioengineered cartilage and the native osteochondral tissue migrated onto the PRP fibers and formed a tissue bridge after 2 weeks of culture. Migratory cells on the tissue bridge expressed higher levels of collagen types II and I ( COL2, COL1), Ki67 and MMP-13 mRNA compared with nonmigratory cells in the bioengineered cartilage. Ki67 and MMP-13–positive cells were found on the edges of the tissue bridge. The tissue bridge accumulated COL1 and COL2 and aggrecan and contained comparable collagen and glycosaminoglycan content to the bioengineered cartilage matrix. The tissue bridge did not reliably develop in the absence of cells from the native osteochondral plug. Conclusion: Bioengineered cartilage formed by bovine chondrocytes contains cells that can migrate on PRP fibers and form cartilaginous tissue. Clinical Relevance: Migratory cells from bioengineered cartilage may promote cartilage integration. Further studies are required to determine the role of migratory cells in integration in vivo.
Health Care Providers’ Knowledge, Attitude, and Practice Regarding Facility-Based Management of Children With Severe Acute Malnutrition in Bangladesh
Authors: Islam Md. Ridwan , Fahim Shah Mohammad , Rasul Md. Golam , Raihan Mohammad Jyoti , Ali Nafi Mohammad , Bulbul Md. Mofijul Islam , Ahmed Tahmeed 
Published: August 2022

Background: Severe acute malnutrition (SAM) contributes to a substantial number of child deaths globally per year. The mortality rates can be lowered markedly if guideline-based management protocol is properly followed. However, case-fatality rates in resource-poor centers remain high even after introducing the guidelines. Perhaps, the lack of adequate knowledge leading to inappropriate management by the health care providers is responsible for such burden. Objective: We aimed to evaluate health care providers’ knowledge, attitude, and practice regarding the facility-based management of children with SAM in Bangladesh. Methods: This was a qualitative study where data were collected cross-sectionally from 4 district and 2 tertiary care hospitals. Twenty-six semi-structured in-depth interviews were conducted among the doctors and nurses involved in inpatient care of SAM. Twenty-eight hours of observation were done in each facility to obtain information regarding the management practices. Results: The doctors had substantial knowledge in managing children with SAM in the facilities. However, knowledge of nurses was found suboptimal when evaluated based on the national guideline. Both doctors and nurses demonstrated favorable attitude toward management of childhood SAM. Identification of SAM at the facilities was poor due to lack of practice in relation to anthropometric measurements. In addition, improper practices related to blood glucose testing, dehydration monitoring, essential micronutrient administration, and follow-up of children with SAM were observed. Conclusion: The study results underscore the importance of taking appropriate measures to enhance knowledge and ensure proper practice in relation to inpatient care of children with SAM according to the national guideline in Bangladesh.
Counter-Narratives Mobilized by Deprived Communities Through Theatre Interventions: Deconstructing and Reframing Master Narratives
Authors: Saldanha Fabio Prado , Pozzebon Marlei , Mailhot Chantale , Le Puil David 
Published: August 2022

Mise au Jeu is a Quebec-based social intervention organization that has been putting on forum theatre – in the Augusto Boal tradition of the theatre of the oppressed – for over 20 years. We investigate how such a non-profit organization creates spaces where members of a deprived communities can elaborate counter-narratives to deconstruct dominant narratives, thereby helping them to make sense of situations of oppression they are living and to act to promote social change. By unpacking counter-narrative strategies and their enabling mechanisms, our study contributes to the narrative tradition in two principal ways. First, while extending Deetz’s work on dominant narratives, we enrich existing understanding of the disruptive power of counter-narratives in situations of social exclusion by bringing to bear the theatrical principles and techniques of Augusto Boal, a missing voice in extant narrative literature. Second, we propose a reflexive discussion related to the political conceptualization of counter-narratives.
Core outcomes were rarely reported overall in systematic reviews on acupuncture for osteoarthritis: a cross-sectional meta-epidemiological study
Authors: Hu Tengyue , Long Youlin , Chen Rui , Yang Zixin , Liu Liqin , Huang Litao , Huang Jin , Liao Ga , Du Liang 
Published: August 2022

Objective: To identify a comprehensive list of outcomes and explore the reporting rate of core outcome sets (COS) and related factors in systematic reviews (SRs) of acupuncture for osteoarthritis (OA). Study design and setting: Databases were searched for the relative SRs. Descriptive statistics were calculated as frequencies and percentages. Binary logistic regression was used to explore the factors affecting the reporting rate of COS. Results: We included 59 SRs. Outcome measures reported in the SRs were classified into 11 domains and 67 unique outcomes. No SR completely reported COS. In COS released in 2016, 75% of outcomes (6/8) were only reported by ⩽5% SRs. In COS released in 2019, the reporting rate was very low (from 0% to 17%) for 73.3% of outcomes (11/15). SRs published in the most recent 5 years had a significantly greater possibility of reporting COS (odds ratio (OR) = 4.74, 95% confidence interval (CI) = 1.33 to 16.88, p = 0.016). Conclusion: Core outcomes were rarely reported in systematic reviews of acupuncture for OA, with considerable heterogeneity in the use of outcomes. The publication of COS in the COMET (Core Outcome Measures in Effectiveness Trials) database may help promote the reporting of COS. We encourage systematic reviewers to use relevant COS.