bluuebunny/crossref_metadata_2025_split huggingface dataset:
Toxicological Evaluation of Acetylsalicylic Acid in Non-Target Organisms: Chronic Exposure on Mytilus galloprovincialis (Lamarck, 1819)
Authors: Pagano M. , Savoca S. , Impellitteri F. , Albano M. , Capillo G. , Faggio C. 
Published: July 2022

Pharmaceuticals are now considered to be established contaminants, and their presence in water poses a real risk not only to the marine ecosystem, as they may adversely affect non-target organisms that are exposed to them, but also indirectly to humans. This is particularly true for the model organism considered in this work, Mytilus galloprovincialis (Lamarck, 1819), a suspensivore and bioaccumulating organism that enters the human food chain. Among the most commonly used over-the-counter medicines, anti-inflammatory drugs certainly feature prominently, with acetylsalicylic acid (ASA) at the top. In this work, M. galloprovincialis specimens were exposed to two concentrations of ASA (10 and 100 μg/L) for 10 and 20 days to evaluate possible alterations in the decrease in regulatory volume (RVD) in digestive gland cells and cell viability of both these cells and hemocytes. In addition, the histopathological condition index of the gills and digestive gland was evaluated. The data obtained showed that chronic exposure to ASA did not alter the cell viability of hemocytes and digestive gland cells but alters the physiological mechanisms of volume regulation in the digestive gland and, in addition, a time-dose reaction to ASA in the gills and digestive gland showing numerous alterations such as lipofuscin deposits and hemocyte infiltration was found. These results confirm the potential toxicity to the marine biota, highlighting the necessity to deepen the knowledge regarding the link between over-the-counter pharmaceuticals and non-target organisms.
Influencing Factors of Mental Health Status of Dentists Under COVID-19 Epidemic
Authors: Li Junping , Guo Jiaoyang , Zhao Juan , Guo Yan , Chen Cheng 
Published: July 2022

ObjectiveTo investigate dentists’ psychological status and influencing factors in Shaanxi Province during the COVID-19 epidemic and assess their perceived wellness.MethodsThe study was conducted among dentists from Shaanxi Province in China. The basic information was collected through the network questionnaire star platform. Depression, Anxiety, and Stress Scales (DASS-42) and Perceived Wellness Survey (PWS) were used to assess subjects’ psychological status and perceived wellness. Univariate linear regression analysis and multivariate analysis were performed on the influencing factors of depression, anxiety, and stress, and t-test and analysis of variance were used to analyze the perceived wellness results.ResultsThe results demonstrated that 33.2% of the surveyed dentists were in a state of depression, 37.1% were anxious, and 34.4% reported stress among 256 subjects. Linear Regression analysis results showed that: “years of working,” “the impact of COVID-19 on their life, work, and sleep,” “worrying about occupational exposure/virus infection,” “lacking the awareness of prevention and control measures,” “overtime work during the epidemic,” “worrying about participating in the supporting work,” and “continuous exhaustion from work” were significant contributors to depression, anxiety, and stress status. In addition, the results of PWS found that each dimension of PWS was correlated with depression, anxiety, and stress state, which indicates the individual’s physical and mental health state was associated with multiple factors.ConclusionCOVID-19 has significantly impacted dentists’ mental health in Shaanxi Province. With these findings, we aim to educate and promote targeted interventions that can be utilized to improve dentists’ mental health by analyzing the influencing factors.
Oral Adverse Events Following COVID-19 Vaccination: Analysis of VAERS Reports
Authors: Riad Abanoub , Põld Ave , Kateeb Elham , Attia Sameh 
Published: July 2022

BackgroundOral adverse events (AEs) following COVID-19 vaccination have been sporadically reported during the previous months, warranting further investigation for their prevalence and suspected relationship with vaccine-elicited immune response.MethodsA retrospective analysis using the Vaccine Adverse Event Reporting System (VAERS) data was conducted to evaluate AEs within the oral cavity (mucosa, tongue, lips, palate, dentition, salivary glands) and AEs involving taste and other sensations. Oral AEs reported after receiving COVID-19 vaccination (test group) and seasonal influenza vaccination (control group) were extracted and cross-tabulated to assess their relative prevalence.ResultsAmong the 128 solicited (suspected) oral AEs, oral paresthesia (0.872%) was most reported after receiving COVID-19 vaccines, followed by the swelling of lips (0.844%), ageusia (0.722%), oral hypoesthesia (0.648%), swollen tongue (0.628%), and dysgeusia (0.617%). The reported prevalence of oral AEs was higher in the COVID-19 vaccine group than in the seasonal influenza group. The distribution pattern of the most reported oral AEs was similar for both COVID-19 and seasonal influenza vaccines. Female sex, older age (&gt;39 years old), primer doses, and mRNA-based COVID-19 vaccines exhibited a higher reported prevalence of oral AEs.ConclusionWithin the limitations of this study, COVID-19 vaccines were found to be associated with rare oral AEs that are predominantly similar to those emerging following seasonal influenza vaccines. The most commonly reported oral AEs were oral paraesthesia (mouth-tingling), lip swelling, and ageusia, representing various pathophysiologic pathways that remain unclear. Taste-related AEs should be acknowledged in the context of the COVID-19 pandemic and the public should be adequately informed about a potential taste dysfunction after receiving the COVID-19 vaccination. Dentists and dental teams need to be aware of the prevalence, severity, and prognosis of oral AEs to inform their patients and increase public confidence in vaccines.
Mini-Percutaneous Nephrolithotomy With an Endoscopic Surgical Monitoring System for the Management of Renal Stones: A Retrospective Evaluation
Authors: Gui Huiming , Wang Hanzhang , Kaushik Dharam , Rodriguez Ronald , Wang Zhiping 
Published: July 2022

PurposeTo compare the outcomes and postoperative quality of life of patients with renal calculi who underwent standard percutaneous nephrolithotomy (sPNL), mini-invasive percutaneous nephrolithotomy (mPNL) or mPNL with an endoscopic surgical monitoring system (ESMS) using a retrospective clinical trial.MethodsEighty-six adult patients with renal stones who were treated with sPNL were retrospectively compared to ninety-two patients who were treated with mPNL between July 2014 and December 2017. Next, further studies were retrospectively conducted using a matched paired method. The ninety-two patients treated with mPNL were divided into two groups based on whether the endoscopic surgical monitoring system (ESMS) was used (ESMS-mPNL vs. non-ESMS-mPNL). The ESMS used strain gauge transducers to measure the inflow and outflow of irrigation solution. Bleeding and fluid absorption during endoscopic surgery could be accurately calculated by computer program in ESMS.ResultsThe fluoroscopy time, complication rate, stone-free status and clinically insignificant residual fragment (CIRF) rate were not significantly different between the two groups (sPNL vs. mPNL). The mPNL group had a significantly longer operation time than the sPNL group, and the mPNL group exhibited a markedly reduced 12-h postoperative visual analogue pain scale (VAS) score, mean hospitalization time, and return to work time, had slightly reduced haemoglobin loss, and underwent more tubeless operations. Moreover, among the 92 patients who underwent mPNL, the operation time (P = 0.090), complication rate (P = 0.996), stone-free status (P = 0.731), CIRF rates (P = 0.125) and number of tubeless operations (P = 0.760) were not significantly different between the two subgroups (non-ESMS-mPNL vs. ESMS-mPNL); however, the patients in the ESMS-mPNL group had significantly longer irrigation times than those in the non-ESMS-mPNL subgroup, along with marked reductions in irrigation fluid, blood loss, haemoglobin loss, 12 h postoperative VAS score, mean hospitalization time, and return to work time.ConclusionsmPNL is less painful than sPNL in patients undergoing treatment for 20–40 mm renal stones. Similar stone-free rates were achieved by the two procedures, but mPNL was superior to sPNL in terms of blood loss, discomfort, hospitalization time and return to work time. We think that ESMS-mPNL is less painful for patients and more efficacious than non-ESMS-mPNL, and ESMS-mPNL achieves a stone-free rate that is similar to non-ESMS-mPNL in patients receiving treatment for 20–40 mm kidney stones.
Correlation Between Serum β2-GPI/oxLDL and the Risk of Cerebral Infarction in Patients with T2DM
Authors: Kuang Wending , Li Yi , Liu Gang , Zhang Yang , Chen Gang , Luo Bang , Kuang Shuangyu 
Published: July 2022

ObjectiveThis study aims to study the correlation between serum β2-glycoprotein I (β2-GPI)/oxidized low-density lipoprotein (oxLDL) and the risk of cerebral infarction in patients with type 2 diabetes (T2DM).MethodsFrom January 2019 to March 2021, 56 patients with T2DM combined with cerebral infarction were chosen as a diabetic cerebral infarction (DCI) group, and 60 patients with simple T2DM were chosen as a T2DM group. In addition, 60 healthy volunteers were recruited as a control group. The essential information of each group was collected, and the serum β2-GPI/oxLDL and inflammatory factor levels in each group were compared. The clinical factors that affect the risk of ischemic cerebral infarction in patients with T2DM were analyzed by a logistic model.ResultsCompared with the control group, the level of serum β2-GPI/oxLDL in the T2DM and DCI groups increased significantly, P &lt; 0.001. Compared with the T2DM group, the serum β2-GPI/oxLDL level in the DCI group increased significantly, P &lt; 0.05. The result of Pearson’s correlation analysis showed that serum β2-GPI/oxLDL was positively correlated with total cholesterol, triglycerides, fasting blood glucose, 2-h postprandial blood glucose, glycosylated hemoglobin, interleukin-6, and tumor necrosis factor (TNF)-α (all P’s &lt; 0.05). Serum TNF-α and β2-GPI/oxLDL were independent risk variates for DCI (P &lt; 0.05). Based on the receiver operating characteristic curve analysis, the values of the area under the curve for TNF-α, serum β2-GPI/oxLDL, and the combined diagnosis of DCI were 0.653 (0.552–0.753), 0.680 (0.583–0.777), 0.739 (0.647–0.831), respectively.ConclusionIn DCI patients, the levels of serum oxLDL/β2-GPI are significantly increased. Serum oxLDL/β2-GPI is an independent risk factor that affects the occurrence of DCI. In addition, the serum β2-GPI/oxLDL level implicates the lipid metabolism and inflammatory status of the internal environment of DCI patients to a certain extent.
The Liberal Social Values of Swedish Healthcare Providers in Women’s Healthcare: Implications for Clinical Encounters in a Diversified Sexual and Reproductive Healthcare
Authors: Eriksson Lise , Tibajev Andrey , Vartanova Irina , Strimling Pontus , Essén Birgitta 
Published: July 2022

Objectives: Women’s healthcare is a potential source of cross-cultural conflicts. Diverging values between healthcare providers and patients challenges the provision of culturally sensitive care and meeting migrant women’s needs. The aim is to investigate healthcare providers’ values in relation to sexual and reproductive rights, gender equality, migration and religion in Swedish sexual and reproductive healthcare.Methods: A national cross-sectional study was carried out. The questionnaire was distributed through a non-probability sample to midwives or other nurses, gynaecologists and obstetricians, and hospital social workers (n = 1,041). Through descriptive statistics, we mapped their values, comparing healthcare provider data to external representative population survey data.Results: Healthcare providers in sexual and reproductive healthcare displayed homogeneous liberal social values, being permissive towards sexual and reproductive rights and restrictive against gender-based violence. They were for gender equality, expressed low anti-immigrant sentiments, and had even more liberal values than the Swedish population and a demographically comparative sub-population.Conclusion: Individuals with very liberal values are selected to work in Swedish sexual and reproductive healthcare. Healthcare providers need self-reflexivity to avoid conflicts in clinical encounters in a diversified society.
PERFIL PSICOSSOCIAL DE ACUMULADORES DE ANIMAIS E IMPLICAÇÕES NA SAÚDE PÚBLICA
Authors: Nardy José Fernando , Missen Tremori Tália , Daniela Babboni Selene , Moreira dos Santos Schmidt Elizabeth , Sousa Rocha Noeme , Langoni Helio 
Published: July 2022

O acúmulo de animais nos domicílios humanos é um tópico emergente no contexto de Saúde Única, caracterizado como um transtorno mental, no qual o indivíduo possui dificuldades em se desfazer de seus animais. O ambiente em que os animais habitam costuma ser insalubre, favorecendo o desenvolvimento de doenças e o comprometimento do bem-estar animal, infringindo direitos legais. O presente estudo teve como objetivo avaliar cinco residências no município de Botucatu, nas quais haviam mais de dez animais. Foram realizadas visitas nessas residências e feita a colheita de fezes dos animais para pesquisar parasitas como: Ancylostoma spp., Cystoisospora sp., Toxocara sp., Trichuris spp. e Giardia spp., além disso aplicou-se um protocolo de perícia para avaliar o Bem-Estar Animal, segundo a adaptação do protocolo desenvolvido por Hammerschmidt (12) no qual o Bem-Estar é classificado em: muito alto, alto, regular, baixo e muito baixo, além disso foi elaborada uma entrevista para identificar fatores epidemiológicos sobre os acumuladores de animais. Foi constatado, por meio de exames coproparasitológicos, principalmente a presença de Ancylostoma spp., Cystoisospora sp. e Giardia spp., em relação ao Bem-estar Animal identificou-se três residências com classificação regular e uma com classificação alto. Já nas entrevistas constatamos o predomínio do sexo masculino, sendo que 60% dos entrevistados eram casados e havia o predomínio do acúmulo de cães e as justificativas para o acúmulo recairam sobre a reprodução indesejada e questões afetivas. Destacamos a importância do médico veterinário para intervir nessas situações, devido ao conhecimento sanitário relacionado à saúde pública, sobretudo em relação as doenças zoonóticas que podem estar presentes nesses ambientes, além do conhecimento que sobre Medicina Veterinária Legal com a intenção de identificar possíveis infrações que possam estar sendo cometidas e consequentemente afetando o Bem-Estar animal. Por fim, ressalta-se a necessidade da abordagem multiprofissional do assunto possibilitando que haja um ambiente em que tanto o animal como os humanos possam desfrutar de condições adequadas de saúde.
Factores sociodemográficos, calidad de vida y afrontamiento del estrés percibido en población ecuatoriana expuesta a la pandemia (covid – 19)
Authors: Pillajo Amagua Cristian Alexander , Pozo Ortega Verónica Elena , Romero Ascuntar Yadira Belén , Soto Cahuatijo Yaqueline Elizabeth 
Published: July 2022

El covid-19, en el ámbito estrés laboral, presenta nuevos retos y una recuperación incierta y lenta que provoca inestabilidad. Los diferentes organismos, como la Organización Mundial de la Salud, defienden la importancia de la salud y bienestar laboral en todos los aspectos, físicos, mentales y sociales ante esta situación de pandemia. En este sentido, como parte de los objetivos de este estudio se tiene evaluar los síntomas psicosomáticos que se han presentado en los trabajadores, a consecuencia del estrés laboral en las organizaciones por covid-19 de la población ecuatoriana. Se trata de un estudio cuali-cuantitativo, de diseño no experimental, con alcance exploratorio y descriptivo. Se aplicó una encuesta online a 518 personas de la población ecuatoriana, quienes consintieron su participación, utilizando el test de WHOQOL–BREF y estrés percibido. Como parte de los resultados, se determina que el 64,7% de los encuestados han sido diagnosticados con covid-19, el 52,4% tiene rara vez sentimientos negativos, el 27,7% casi nunca se han sentidos afectados como si algo grave fuera a ocurrir inesperadamente con la pandemia y el 10,1% casi siempre se han sentido incapaz de controlar las cosas importantes de su vida por la pandemia. Se reportan diferentes porcentajes de personas contagiadas con el covid-19, también se puede observar que los estados emocionales negativos de depresión, ansiedad y estrés, en un porcentaje mayor no ha ocurrido; por otro lado, la mayoría tiene una calidad de vida satisfactoria en el aspecto psicológico, salud física, relaciones sociales y ambiental; se percibe un estrés relacionado con la pandemia en la mayoría de los participantes.
Pengaruh Dukungan Rekan Kerja terhadap Kualitas Pekerjaan pada Karyawan
Authors: Hanif Muhammad , Zamzabila Bintan , Darmawan Zharfan Amadeus 
Published: July 2022

Saat terjun pada dunia kerja yang baru, maka seseorang akan mulai berusaha untuk beradaptasi dengan lingkungan, sistem serta orang baru yang ada dalam lingkup pekerjaannya tersebut. Dalam hal ini diperlukannya dukungan rekan kerja pada proses adaptasi. Ketika seseorang tidak mendapat dukungan serta merasa tidak ada yang mempedulikannya maka hal tersebut dapat mempengaruhi kualitas kinerja seseorang dalam menjalankan tugas-tugasnya. Oleh karena itu, kami melakukan penelitian literatur ini untuk mencari jawaban mengenai pengaruh dukungan rekan kerja terhadap kualitas pekerjaan. Artikel ini bertujuan untuk meninjau secara sistematis pengaruh dukungan rekan kerja terhadap kualitas pekerjaan. Kami mengidentifikasi artikel terkait topik melalui database Google Scholar, Proquest, dan Inovbiz. Berdasarkan hasil dari penelitian yang telah dilakukan para peneliti dalam lima jurnal yang menjadi referensi kami, maka dapat diambil kesimpulan bahwa hasil Systematic Literature Review atau SLR menunjukkan, dukungan rekan kerjasangat dibutuhkan oleh seorang karyawan agar dapat menunjang kualitas kinerjanya di suatu perusahaan dan dukungan rekan kerja terbukti berpengaruh terhadap kinerja tugas karyawan.
ElectrodeNet – A Deep Learning Based Sound Coding Strategy for Cochlear Implants
Authors: Huang Enoch Hsin-Ho , Chao Rong , Tsao Yu , Wu Chao-Min 
Published: July 2022

<p>ElectrodeNet, a deep-learning based sound coding strategy for the cochlear implant (CI), is proposed in this study. </p>
<p>ElectrodeNet emulates the ACE strategy by replacing the conventional envelope detection using various artificial neural networks, and the extended ElectrodeNet-CS strategy further incorporates the channel selection (CS) in the network. Network models of deep neural network (DNN), convolutional neural network (CNN), and long short-term memory (LSTM) were trained using the Fast Fourier Transformed bins and electrode stimulation patterns from the processing of the ACE strategy for clean speech. Objective speech understanding using short-time objective intelligibility (STOI) and normalized covariance metric (NCM) was estimated for ElectrodeNet with the factors of network architecture, dataset language, and noise type using CI simulations. Subjective listening tests for vocoded Mandarin speech were conducted with normal-hearing listeners to measure sentence recognition scores. DNN, CNN, and LSTM based ElectrodeNets exhibited strong correlations to ACE in objective and subjective scores using mean squared error (MSE), linear correlation coefficient (LCC) and Spearman’s rank correlation coefficient (SRCC). The ElectrodeNet-CS strategy was capable of producing N-of-M compatible electrode patterns using a modified DNN network to embed maxima selection, and to perform in similar or even slightly above average in STOI and sentence recognition compared to ACE. The methods and findings in this study demonstrated the feasibility and potential of using deep learning in CI sound coding strategy.</p>
Kajian Yuridis Pengaturan Daluwarsa dalam Tindak Pidana Pemalsuan Surat
Authors: Armindo Yoseph Yohan 
Published: July 2022

Pemalsuan surat merupakan tindak pidana yang akibatnya tidak dirasakan langsung oleh korban. Berdasarkan Putusan Nomor 3/Pid.Pra/2018/PN Kpg hak dari tersangka yang diuntungkan seharusnya korbanlah yang harus diuntungkan sesuai dengan data atau kasus yang ditangani tindak pidana pemalsuan surat tersebut belum daluwarsa. Tujuan yang ingin dicapai dari pelaksanaan penelitian ini yaitu untuk menganalisis pengaturan daluwarsa ditetapkan untuk menghapus atau meniadakan tuntutan pidana pada seseorang, untuk menganalisis implementasi dari ketentuan daluwarsa dalam praktik penanganan pemalsuan surat dan merumuskan formulasi kebijakan pidana tentang daluwarsa dalam undang-undang pidana yang akan datang. Metode penelitian adalah normatif dengan pendekatan konseptual, kasus dan perundang-undangan. Hasil dari penelitian ini menunjukkan bahwa rasio legis pengaturan daluwarsa ditetapkan untuk menghapus atau meniadakan tuntutan pidana adalah faktor kesulitan pembuktian serta menemukan tiga hal yang memengaruhi kesulitan mengungkap perkara.
Studi Komparasi Strategi Sustainable Livelihood Kampung Heritage Kajoetangan dan Kampung Ornament Tjelaket Kota Malang
Authors: Virgin Pendix Annisa , Ayu Turniningtyas , Siregar Johannes Parlindungan 
Published: July 2022

Latar belakang: Pariwisata saat ini ditujukan untuk pembangunan wisata yang berkelanjutan. Kebijakan pembangunan pariwisata berkelanjutan berfokus pada penggunaan sumber daya alam dan sumber daya manusia untuk jangka waktu panjang.
Tujuan penelitian: Penelitian ini bertujuan untuk merumuskan strategi sustainable livelihood pada Kampung Wisata Heritage Kajoetangan dan Kampung Wisata Ornament Tjelaket Kota Malang.
Metode penelitian: Penelitian ini termasuk penelitian kausal komparatif dengan pendekatan kuantitatif, yang bersifat membandingkan dua kelompok atau lebih dari suatu variabel tertentu.
Hasil penelitian: Tingkat penghidupan menjadi 3 kategori yakni rendah, sedang dan tinggi. Tingkat penghidupan masyarakat Kampung Heritage Kajoetangan tergolong dalam kategori sedang atau belum berkelanjutan. Tingkat penghidupan masyarakat Kampung Ornament Tjelaket tergolong dalam kategori sedang atau belum berkelanjutan (skor 2,00). Masyarakat Kampung Heritage Kajoetangan dominan menggunakan modal alam,modal fisik dan modal sosial. Modal alam yang dimanfaatkan Kampung Heritage Kajoetangan seperti pemanfaatan lahan, asal air bersih dan akses air bersih. Berdasarkan tahun 2018-2019 masyarakat Kampung Heritage Kajoetangan telah memaksimalkan pemanfaatan lahannya/lokasi tempat tinggal mereka dengan cara memanfaatkan potensi wisata.
Kesimpulan: Kondisi aset penghidupan kedua kampung tersebut tergolong dalam kategori sedang atau belum berkelanjutan. Kampung Heritage Kajoetangan memiliki skor 2,11 (belum berkelanjutan), hal ini dipengaruhi oleh nilai pemanfaatan modal manusia dan modal social yang memiliki nilai rata-rata sedang (belum berkelanjutan) dan modal ekonomi yang tergolong rendah (tidak berkelanjutan). Modal manusia memiliki skor 2,04 (belum berkelanjutan), karena rendahnya persentase tingkat pendidikan dan pekerjaan masyarakat Heritage Kajoetangan. Rendahnya pendidikan masyarakat Heritage Kajoetangan ini sangat berpengaruh terhadap rendahnya pendapatan seseorang karena tingkat pendidikan yang rendah mengakibatkan seseorang cenderung memiliki wawasan, keterampilan dan pengetahuan yang kurang memadai untuk kehidupannya, karena sejatinya pendidikan merupakan kebutuhan pokok yang harus dipenuhi oleh setiap orang, bila kebutuhan pokok seseorang tidak dapat terpenuhi, maka hal itulah yang menjadi salah satu penyebab kemiskinan.