bluuebunny/crossref_metadata_2025_split huggingface dataset:
An International Commentary on Dysphagia and Dysphonia During the COVID-19 Pandemic
Authors: Miles Anna , McRae Jackie , Clunie Gemma , Gillivan-Murphy Patricia , Inamoto Yoko , Kalf Hanneke , Pillay Mershen , Pownall Susan , Ratcliffe Philippa , Richard Theresa , Robinson Ursula , Wallace Sarah , Brodsky Martin B. 
Published: January 2022

AbstractCOVID-19 has had an impact globally with millions infected, high mortality, significant economic ramifications, travel restrictions, national lockdowns, overloaded healthcare systems, effects on healthcare workers’ health and well-being, and large amounts of funding diverted into rapid vaccine development and implementation. Patients with COVID-19, especially those who become severely ill, have frequently developed dysphagia and dysphonia. Health professionals working in the field have needed to learn about this new disease while managing these patients with enhanced personal protective equipment. Emerging research suggests differences in the clinical symptoms and journey to recovery for patients with COVID-19 in comparison to other intensive care populations. New insights from outpatient clinics also suggest distinct presentations of dysphagia and dysphonia in people after COVID-19 who were not hospitalized or severely ill. This international expert panel provides commentary on the impact of the pandemic on speech pathologists and our current understanding of dysphagia and dysphonia in patients with COVID-19, from acute illness to long-term recovery. This narrative review provides a unique, comprehensive critical appraisal of published peer-reviewed primary data as well as emerging previously unpublished, original primary data from across the globe, including clinical symptoms, trajectory, and prognosis. We conclude with our international expert opinion on what we have learnt and where we need to go next as this pandemic continues across the globe.
Occurrence and relevance of Mycoplasma spp. in free-ranging pheasants from northwestern Germany
Authors: Fischer Luisa , Liebing Jennifer , Völker Iris , Baudler Liane , Gethöffer Friederike , Voigt Ulrich , Heffels-Redmann Ursula , Wohlsein Peter , Siebert Ursula , Lierz Michael 
Published: January 2022

AbstractSince 2008/2009, the population of free-ranging ring-necked pheasants was recorded to decrease all over Germany. Various Mycoplasma (M.) spp. are causing severe respiratory signs in captive game bird species. Furthermore, M. gallisepticum is responsible for massive die-offs in consequence to severe conjunctivitis in house finches in the USA. Therefore, the prevalence of mycoplasmas in free-ranging pheasants was investigated and a potential impact on the population decline of pheasants discussed. Within this study, 150 free-ranging pheasants were sampled via tracheal swabs and tissue samples of the trachea and the periorbital skin, as the latter displayed inflammatory alterations in previous studies. In total, 177 samples were investigated for the presence of mycoplasmas using cultural and molecular biological methods. In 76 birds, necropsy was performed additionally. In total, 73.7% (51/76) of the examined pheasants had periorbital skin alterations. Furthermore, 64.4% (114/177) of the samples tested positive for mycoplasmas via PCR. Overall, 102/177 samples (57.6%, 78/105 tracheal swabs, 19/51 skin tissue, 5/21 trachea tissue) tested positive for mycoplasmas via culture. Mycoplasma gallinaceum (n = 50), M. pullorum (n = 45), M. glycophilum (n = 43), M. iners (n = 11), and M. gallinarum (n = 5) were frequently isolated. In 45 cases (45.9%), multiple Mycoplasma spp. were isolated from one sample. All examined samples tested negative for M. gallisepticum. Of 51 skin samples investigated for mycoplasmas, 24 (47.1%) showed inflammatory skin alterations in histology, and 58.3% (14/24) of these samples tested positive for Mycoplasma spp. additionally. Overall, there was a significant correlation between inflammatory altered skin samples and the detection of mycoplasmas in periorbital skin samples. Based on the present results, the isolated Mycoplasma spp. may play a role as facultative agents for the observed inflammatory skin alterations. However, additional investigation is needed to confirm this presumption.
Associations Between Pornography Consumption, Sexual Flexibility, and Sexual Functioning Among Austrian Adults
Authors: Komlenac Nikola , Hochleitner Margarethe 
Published: January 2022

AbstractTo date, only a few studies have examined the associations between pornography consumption and sexual functioning. The Acquisition, Activation, Application Model (3AM) indicates that the frequency of pornography consumption and the perceived realism of pornography may influence whether sexual scripts are acquired from viewed pornography. Having sexual scripts that are alternative to their preferred sexual behaviors may help people switch to alternative sexual behavior when sexual problems arise. The current study analyzed whether frequent pornography consumption was associated with greater sexual flexibility and greater sexual functioning. Additionally, the perceived realism of pornography consumption was tested as a moderator of those associations. At an Austrian medical university, an online cross-sectional questionnaire study was conducted among 644 medical students (54% women and 46% men; Mage = 24.1 years, SD = 3.8). The participants were asked about their pornography consumption, partnered sexual activity, sexual flexibility, perceived realism of pornography, and sexual functioning. Manifest path analyses revealed direct and indirect associations between frequent pornography consumption and greater sexual functioning through greater sexual flexibility in women but not in men. Perceived realism did not moderate those associations. In conclusion, our study was in line with previous studies that found no significant associations between men’s pornography consumption and sexual functioning in men. However, some women may expand their sexual scripts and learn new sexual behaviors from pornography consumption, which may help with their sexual functioning.
Expected passes
Authors: Anzer Gabriel , Bauer Pascal 
Published: January 2022

AbstractPasses are by far football’s (soccer) most frequent event, yet surprisingly little meaningful research has been devoted to quantify them. With the increase in availability of so-called positional data, describing the positioning of players and ball at every moment of the game, our work aims to determine the difficulty of every pass by calculating its success probability based on its surrounding circumstances. As most experts will agree, not all passes are of equal difficulty, however, most traditional metrics count them as such. With our work we can quantify how well players can execute passes, assess their risk profile, and even compute completion probabilities for hypothetical passes by combining physical and machine learning models. Our model uses the first 0.4 seconds of a ball trajectory and the movement vectors of all players to predict the intended target of a pass with an accuracy of $$93.0\%$$

93.0
%

for successful and $$72.0\%$$

72.0
%

for unsuccessful passes much higher than any previously published work. Our extreme gradient boosting model can then quantify the likelihood of a successful pass completion towards the identified target with an area under the curve (AUC) of $$93.4\%$$

93.4
%

. Finally, we discuss several potential applications, like player scouting or evaluating pass decisions.
Strengthening ties towards a highly-connected world
Authors: Matakos Antonis , Gionis Aristides 
Published: January 2022

AbstractOnline social networks provide a forum where people make new connections, learn more about the world, get exposed to different points of view, and access information that were previously inaccessible. It is natural to assume that content-delivery algorithms in social networks should not only aim to maximize user engagement but also to offer opportunities for increasing connectivity and enabling social networks to achieve their full potential. Our motivation and aim is to develop methods that foster the creation of new connections, and subsequently, improve the flow of information in the network. To achieve our goal, we propose to leverage the strong triadic closure principle, and consider violations to this principle as opportunities for creating more social links. We formalize this idea as an algorithmic problem related to the densest k-subgraph problem. For this new problem, we establish hardness results and propose approximation algorithms. We identify two special cases of the problem that admit a constant-factor approximation. Finally, we experimentally evaluate our proposed algorithm on real-world social networks, and we additionally evaluate some simpler but more scalable algorithms.
Ad-VT enhances the sensitivity of chemotherapy-resistant lung adenocarcinoma cells to gemcitabine and paclitaxel in vitro and in vivo
Authors: Song Gaojie , Shang Chao , Sun Lili , Li Yiquan , Zhu Yilong , Xiu Zhiru , Liu Zirui , Li Yaru , Yang Xia , Ge Chenchen , Fang Jinbo , Jin Ningyi , Li Xiao 
Published: January 2022

SummaryBackground One of the main challenges in the clinical treatment of lung cancer is resistance to chemotherapeutic drugs. P-glycoprotein (P-gp)-mediated drug resistance is the main obstacle to successfully implementing microtubule-targeted tumor chemotherapy. Purpose In this study, we explored the effect of Ad-hTERTp-E1a-Apoptin (Ad-VT) on drug-resistant cell lines and the molecular mechanism by which Ad-VT combined with chemotherapy affects drug-resistant cells and parental cells. Methods In vitro, cell proliferation, colony formation, resistance index (RI), apoptosis and autophagy assays were performed. Protein expression was analyzed by Western blotting. Finally, a xenograft tumor model in nude mice was used to detect tumor growth and evaluate histological characteristics. Results Our results showed that Ad-VT had an obvious killing effect on A549, A549/GEM and A549/Paclitaxel cancer cells, and the sensitivity of drug-resistant cell lines to Ad-VT was significantly higher than that of parental A549 cells. Compared with A549 cells, A549/GEM and A549/Paclitaxel cells had higher autophagy levels and higher viral replication ability. Ad-VT decreased the levels of p-PI3k, p-Akt and p-mTOR and the expression of P-gp. In vivo, Ad-VT combined with chemotherapy can effectively inhibit the growth of chemotherapy-resistant tumors and prolong the survival of mice. Conclusions Thus, the combination of Ad-VT and chemotherapeutic drugs will be a promising strategy to overcome chemoresistance.
Modelling multivariate data using product copulas and minimum distance estimators: an exemplary application to ecological traits
Authors: Liebscher Eckhard , Taubert Franziska , Waltschew David , Hetzer Jessica 
Published: January 2022

AbstractModelling and applying multivariate distributions is an important topic in ecology. In particular in plant ecology, the multidimensional nature of plant traits comes with challenges such as wide ranges in observations as well as correlations between several characteristics. In other disciplines (e.g., finances and economics), copulas have been proven as a valuable tool for modelling multivariate distributions. However, applications in ecology are still rarely used. Here, we present a copula-based methodology of fitting multivariate distributions to ecological data. We used product copula models to fit multidimensional plant traits, on example of observations from the global trait database TRY. The fitting procedure is split into two parts: fitting the marginal distributions and fitting the copula. We found that product copulas are well suited to model ecological data as they have the advantage of being asymmetric (similar to the observed data). Challenges in the fitting were mainly addressed to limited amount of data. In view of growing global databases, we conclude that copula modelling provides a great potential for ecological modelling.
Effect of biomass-based carbon capture on the sustainability and economics of pulp and paper production in the Nordic mills
Authors: Kuparinen Katja , Lipiäinen Satu , Vakkilainen Esa , Laukkanen Timo 
Published: January 2022

AbstractBioenergy with carbon capture and storage (BECCS) is one of the key negative emission technologies (NETs). Large-scale implementation of BECCS has been criticized of the associated increase in land use. The existing large Nordic pulp and paper production units enable BECCS deployment without additional land use, as they currently release large amounts of bio-based carbon dioxide (CO2). The application of BECCS in pulp mills has been found technically feasible in earlier studies. This study explores key factors that affect the propensity to invest in BECCS in different types of existing European pulp and paper mills. The results give fresh understanding on the effects of BECCS on the market price of pulp and paper products and the required level of incentives. Based on statistical data, the marginal carbon dioxide credit (€ per ton CO2) to make BECCS profitable was derived. The results show that the required level of credit greatly depends on the mill type and details and that the feasibility of BECCS does not clearly correlate with the economic performance or the measured efficiency of the mill. The most promising mill type, a market kraft pulp mill, would find BECCS profitable with a credit in the range of 62–70 €/tCO2 and a credit of 80 €/tCO2 would decrease pulp production costs by 15 €/tproduct on average if 50% of CO2 emissions was captured. The EU Emission Trading System (ETS) is the main policy instrument to achieve the climate targets related to fossil energy use, but does not yet contemplate bio-based emissions.
Vaporization Thermodynamics of Pyrrolidinium, Pyridinium, and Imidazolium-Based Ionic Liquids Bearing the Bis(fluorosulfonyl)imide [FSI] and the Bis(trifluoromethylsulfonyl)imide [NTf2] Anions
Authors: Zaitsau Dzmitry H. , Verevkin Sergey P. 
Published: January 2022

AbstractNew experimental vapor pressures in the range 407 K to 460 K and vaporization enthalpy of the ionic liquids (IL) N-alkyl-N-methyl-pyrrolidinium bis(fluorosulfonyl)imide ionic liquids have been measured using quartz crystal microbalance. The absolute vapor pressures and vaporization enthalpies were compared with analogous pyrrolidinium-based ILs with the bis(trifluoromethanesulfonyl)imide anion. The evaluated difference in vaporization enthalpy of ILs with bis(fluorosulfonyl)imide and bis(trifluoromethanesulfonyl)imide anions allowed for estimation of corresponding property for a wide set of ILs with bis(fluorosulfonyl)imide anion. The results are relevant to chemical engineering calculations of processes involving ILs as reaction and separation media.
Spanish and Swedish teachers’ perspective of teaching STEM and robotics in preschool – results from the botSTEM project
Authors: Fridberg Marie , Redfors Andreas , Greca Ileana M. , Terceño Eva M. García 
Published: January 2022

AbstractThis article describes outcomes from the Erasmus + project botSTEM, involving a theoretical framework for Science, Technology, Engineering & Technology (STEM) and robotics and teaching activities for preschool teachers and teachers educating children 4–8 years old. Spanish and Swedish preschool teachers’ self-efficacy and views of teaching STEM and robotics are presented, using a mixed methodology based on a questionnaire and focus group interviews. The 3-year long project has improved the preschool teachers’ self-efficacy in STEM and robotics teaching, as described in a questionnaire answered by the preschool teachers after the project. Possibilities in STEM and robotics teaching experienced by them include an increase in children’s agency, knowledge and interest, and the obstacles are mainly structural or technical. Robotics teaching also supports children with special needs when interacting with peers. The results from the botSTEM project point to the benefit of supported long-term professional development for STEM and robotics teaching in preschools.
Stress-Aware Periodic Test of Interconnects
Authors: Sadeghi-Kohan Somayeh , Hellebrand Sybille , Wunderlich Hans-Joachim 
Published: January 2022

AbstractSafety-critical systems have to follow extremely high dependability requirements as specified in the standards for automotive, air, and space applications. The required high fault coverage at runtime is usually obtained by a combination of concurrent error detection or correction and periodic tests within rather short time intervals. The concurrent scheme ensures the integrity of computed results while the periodic test has to identify potential aging problems and to prevent any fault accumulation which may invalidate the concurrent error detection mechanism. Such periodic built-in self-test (BIST) schemes are already commercialized for memories and for random logic. The paper at hand extends this approach to interconnect structures. A BIST scheme is presented which targets interconnect defects before they will actually affect the system functionality at nominal speed. A BIST schedule is developed which significantly reduces aging caused by electromigration during the lifetime application of the periodic test.
Monitoring protein unfolding transitions by NMR-spectroscopy
Authors: Dreydoppel Matthias , Balbach Jochen , Weininger Ulrich 
Published: January 2022

AbstractNMR-spectroscopy has certain unique advantages for recording unfolding transitions of proteins compared e.g. to optical methods. It enables per-residue monitoring and separate detection of the folded and unfolded state as well as possible equilibrium intermediates. This allows a detailed view on the state and cooperativity of folding of the protein of interest and the correct interpretation of subsequent experiments. Here we summarize in detail practical and theoretical aspects of such experiments. Certain pitfalls can be avoided, and meaningful simplification can be made during the analysis. Especially a good understanding of the NMR exchange regime and relaxation properties of the system of interest is beneficial. We show by a global analysis of signals of the folded and unfolded state of GB1 how accurate values of unfolding can be extracted and what limits different NMR detection and unfolding methods. E.g. commonly used exchangeable amides can lead to a systematic under determination of the thermodynamic protein stability. We give several perspectives of how to deal with more complex proteins and how the knowledge about protein stability at residue resolution helps to understand protein properties under crowding conditions, during phase separation and under high pressure.
Developing a Public Health Maternal and Child Health Training Program: Lessons Learned from Five Schools of Public Health
Authors: Bozlak Christine T. , Brown Qiana L. , Davis Renee , de Long Rachel , Howard Melissa M. , Lassiter Teri E. , Perez-Patron Maria J. , Taylor Brandie DePaoli , Turchi Renee , Tissue Michelle Menser 
Published: January 2022

AbstractMaternal and child health (MCH), as a core sub-field of public health, continues to be an essential area in which additional workforce development and investment are needed. Recent public health workforce assessments in the United States reveal there will be a significant number of vacancies in MCH public health positions in the near future, creating the need for a well-trained and skilled public health MCH workforce. In order to address this potential critical workforce gap, the U.S. Department of Health and Human Services, Health Resources and Services Administration’s Maternal and Child Health Bureau initiated the Maternal and Child Health Public Health Catalyst Program in 2015 to support the creation of MCH training programs in accredited schools of public health that previously did not have a MCH concentration. This article details the accomplishments and lessons learned from the first five MCH Catalyst Program grantees: Drexel University; Florida International University; Rutgers, The State University of New Jersey; Texas A&M University; and the University at Albany.
A Multimodal MR Imaging Study of the Effect of Hippocampal Damage on Affective and Cognitive Functions in a Rat Model of Chronic Exposure to a Plateau Environment
Authors: Zhu Dongyong , He Bo , Zhang Mengdi , Wan Yixuan , Liu Ruibin , Wang Lei , Zhang Yi , Li Yunqing , Gao Fabao 
Published: January 2022

AbstractProlonged exposure to high altitudes above 2500 m above sea level (a.s.l.) can cause cognitive and behavioral dysfunctions. Herein, we sought to investigate the effects of chronic exposure to plateau hypoxia on the hippocampus in a rat model by using voxel-based morphometry, creatine chemical exchange saturation transfer (CrCEST) and dynamic contrast-enhanced MR imaging techniques. 58 healthy 4-week-old male rats were randomized into plateau hypoxia rats (H group) as the experimental group and plain rats (P group) as the control group. H group rats were transported from Chengdu (500 m a.s.l.), a city in a plateau located in southwestern China, to the Qinghai–Tibet Plateau (4250 m a.s.l.), Yushu, China, and then fed for 8 months there, while P group rats were fed in Chengdu (500 m a.s.l.), China. After 8 months of exposure to plateau hypoxia, open-field and elevated plus maze tests revealed that the anxiety-like behavior of the H group rats was more serious than that of the P group rats, and the Morris water maze test revealed impaired spatial memory function in the H group rats. Multimodal MR imaging analysis revealed a decreased volume of the regional gray matter, lower CrCEST contrast and higher transport coefficient Ktrans in the hippocampus compared with the P group rats. Further correlation analysis found associations of quantitative MRI parameters of the hippocampus with the behavioral performance of H group rats. In this study, we validated the viability of using noninvasive multimodal MR imaging techniques to evaluate the effects of chronic exposure to a plateau hypoxic environment on the hippocampus.
Evaluation of the reactivity, selectivity and lifetime of hydrotalcite-based catalysts using isopropanol as probe molecule
Authors: Abdelsadek Zoulikha , Gonzalez-Cortes Sergio , Bali Feroudja , OuizaCherifi  , Halliche Djamila , Masset Patrick J. 
Published: January 2022

AbstractHydrotalcite catalysts derived from NiAl and NiAlMg mixed oxides were successfully prepared by coprecipitation at a constant pH of 11. Physicochemical methods were investigated to determine their structural and textural properties. Using isopropanol as a probe molecule, the acid–base properties of the catalysts were investigated, and the evaluation of reactivity, selectivity and lifetime was established.
The Influence of Gender Equality on Volunteering Among European Senior Citizens
Authors: Sánchez-García Julia , Gil-Lacruz Ana Isabel , Gil-Lacruz Marta 
Published: January 2022

AbstractThis research analyzes how gender equality influences the participation of European senior citizens in a range of volunteering activities (Social Awareness, Professional and Political, Education, and Religion). The main contribution is the simultaneous consideration of different levels of data aggregation: individual, national and welfare system. This allows conclusions to be drawn on the effects of variables linked to sociodemographic characteristics, gender equality and welfare systems. The empirical estimation utilised microdata from the World Values Survey (2005/09 and 2010/14) and the United Nations Development Programme. Results suggest that the European senior citizens appear to believe that they are more equal than the official statistics of their countries indicate. Men are more likely to participate in professional and education activities; women are more likely to be involved in religious organisations. Welfare systems influence volunteering behaviours. The promotion of macro-policies for gender equality could be important for increasing participation in non-profit organisations.