bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical Characteristics of Hospitalized and Home Isolated Covid-19 Patients with Type 1 Diabetes
Authors: Zulfiqar Saba , Sarwar Mohammad Arif , Javed Alyia , Hafeez Javaria , Shahid Fawzia , Akram Waseem 
Published: August 2022

Aim: To investigate pathological conditions of COVID-19 individuals having type 1 diabetes throughout hospitalization and home isolation.
Methods: This retrospective analysis included 32 COVID-19 in addition T1D individuals who sought therapy at Services Hospital, Lahore, between May 1, 2021, and July 30, 2021. Patient information was obtained from electronic medical records.
Results: 23.8 percent of 32 COVID-19 individuals having T1D needed hospitalization, whereas 78.1 percent needed home isolation. 10.6 percent (4/35) of the study group had hypertension, 23.7 percent (8/34) had chronic pulmonary disease (CPD), 17.9 percent (7/35) had thyroid abnormalities, and 19.9 percent (7/37) had celiac disease. Of the 36 individuals tested, 66.9 percent (21/37) were classified as normal, 29.3 percent (10/36) as having serious kidney illness (CKD) II, and 4.3 percent (2/37) as having end-stage renal failure. The most facing health reported amongst hospitalized individuals remained nausea and vomiting (72.5 percent; 5/7), fever (57.1 percent; 4/7), cough (42.8 percent; 3/7), sore throat (42.8 percent; 3/7), stomach discomfort (42.8 percent; 3/7), and dyspnea (42. percent; 3/7). Diabetic ketoacidosis (71.4 percent; 5/7) was the most prevalent cause for hospitalization, followed by bacterial pneumonia (14.3 percent; 1/7), fever (14.3 percent; 1/7), sore throat (14.3 percent; 1/7), severe hyperglycemia (14.3 percent; 1/7), and COVID-19 pneumonia (14.3 percent; 1/7). Excluding for harshness of COVID-19 (p 14 0.0001), no demographic or medical indicators revealed statistically substantial changes between patients needing hospitalization also those who could be isolated at home.
Conclusion: The popular of COVID-19 T1D individuals healed at home without conservative treatment. The most prevalent cause for admission was diabetic ketoacidosis.
A “INVENÇÃO DO TRABALHO”: historicidade de um conceito nas obras de André Gorz, Dominique Méda, Françoise Gollain e Serge Latouche
Authors: Cardoso Machado Nuno Miguel 
Published: August 2022

Após a publicação de Adeus ao Proletariado, em 1980, o entendimento do trabalho como uma atividade historicamente específica da modernidade capitalista é uma das traves-mestras do edifício teórico construído por André Gorz. O trabalho está intimamente associado ao surgimento de uma esfera econômica desvinculada da sociedade e, na qualidade de trabalho abstrato, ao fim, em si mesmo irracional, da valorização do valor. Neste artigo, pretendemos caracterizar detalhadamente a evolução do conceito de trabalho nas principais obras de Gorz e, depois, comparar a noção gorziana acerca da historicidade do trabalho com as ideias de três autores francófonos: Dominique Méda, Françoise Gollain e Serge Latouche. Procuraremos aferir as semelhanças e as divergências entre os autores mencionados. Finalmente, será salientado que as razões aventadas para o devir histórico do trabalho podem ser mais bem entendidas no contexto embrionário comum da “revolução militar”, no século XVI, que inaugurou a era moderna no mundo ocidental.
ANDRÉ GORZ, PELA INCONDICIONALIDADE DA RENDA
Authors: Gollain Françoise 
Published: August 2022

André Gorz partilhou com defensores da renda de existência o diagnóstico segundo o qual o atual sistema de redistribuição não está adaptado à flexibilidade e à precarização do emprego como um dado estrutural de mercado de trabalho. Entretanto, além do desejo de remediar essas disfunções e de assegurar uma seguridade existencial a cada um, ele concebia a outorga de uma renda garantida a todos como um dos instrumentos de uma transformação radical e emancipadora. Nessa perspectiva, a renda de existência está articulada a duas séries de medidas: redução do tempo de trabalho e expansão das atividades autônomas. O exame do lugar acordado a cada um dos termos desse tríptico permite perceber a significativa mudança de Gorz para um degrau mais elevado da incondicionalidade da renda. Para além dessa virada, buscamos ressaltar a permanência de seu projeto político (e filosófico) fundamental: restringir as relações mercantis e avançar para uma sociedade caracterizada por formas de cooperação não mercantis.
NARRATIVAS E TRAJETÓRIAS: abordagens metodológicas a partir da UNILAB
Authors: Castro Benevides Mario Henrique , Lopes Pinheiro Carlos Henrique 
Published: August 2022

Tomando a realidade da Universidade da Integração Internacional da Lusofonia Afro-brasileira (UNILAB) como ponto de partida, discutem-se abordagens teórico-metodológicas das ciências sociais e sua revisão no contexto da “lusofonia”. Diversas metodologias qualitativas são abordadas e desnudadas, considerando-se o contexto de sujeitos sociais ligados aos países da CPLP e ao mundo colonial. Na busca por uma sociologia das falas e uma geografia dos discursos, damos ênfase à importância do cotidiano como base de trabalho e reflexão epistemológica. Pensá-lo continuamente a partir das diferenças relacionais que o contexto lusófono provoca, é parte do resultado da reflexão do pesquisador nessa seara. NARRATIVES AND TRAJECTORIES: methodological approaches from UNILABTaking the reality of the Universidade da Integração Internacional da Lusofonia Afrobrasileira (UNILAB) as a starting point, theoreticalmethodological approaches of the social sciences and their revision in the context of “lusophony” are discussed. Several qualitative methodologies are addressed and detailed, considering the context of social subjects linked to the CPLP countries and the colonial world. In the search for a sociology of speech and a geography of discourses, we emphasize the importance of daily life as a basis for work and epistemological reflection. To think of it continually from the relational differences that the lusophone context causes, is part of the result of the researcher’s considerations in this field.Keywords: Methodology. Lusophony. Narratives. Trajectory studies. Higher education. NARRATIVES ET TRAJECTOIRES: approches méthodologiques sur la base de l’UNILABEn prenant comme point de départ la réalité de l’Université pour l’Intégration Internationale de la Lusophonie Afro-brésilienne (UNILAB), nous analysons les approches théoriques et méthodologiques des sciences sociales et nous la reconsidérons dans le cadre de la « lusophonie ». Plusieurs méthodologies qualitatives sont abordées et mises à nu dans le contexte des sujets sociaux liés aux pays de la CPLP et au monde colonial. À la recherche d’une sociologie de la parole et d’une géographie des discours, nous insistons sur l’importance de la vie quotidienne prise comme base de travail et de réflexion épistémologique. Y penser constamment sans perdre de vue les différences relationnelles provoquées par le contexte lusophone, fait partie du résultat de la réflexion du chercheur dans ce champ. Mots-clés: Méthodologie. Lusophonie. Récits. Études de trajectoire. Enseignement supérieur.
Pain‐Related Risk Factors Among Radiologic Stages of Knee Osteoarthritis: Data From the Osteoarthritis Initiative
Authors: He Zi‐Jun , Li Shi‐Lin , Zou Ji‐Hua , Gong Ze , He Long‐Long , Zhang Zhuo‐Dong , Lu Peng‐Cheng , Fan Tao , Chen Rong , Chen Zhi , Zhao Yi‐Jin , Zeng Qing , Huang Guo‐Zhi 
Published: August 2022

ObjectiveTo investigate whether risk factors related to pain vary at different stages of knee osteoarthritis (OA).MethodsIndividuals from the Osteoarthritis Initiative with available Kellgren/Lawrence (K/L) grade and numerical rating scale (NRS) data at baseline were included in this study. Pain severity was classified into 3 categories based on NRS scores: no pain, mild pain, and moderate/severe pain. Knee OA severity was stratified into 4 categories according to the K/L system. Pain risk factors were evaluated using generalized ordinal logistic regression analysis, and a heatmap was created to compare differences in standardized regression coefficients between subgroups of patients with different knee OA severities.ResultsA total of 4,446 subjects were included in this study: 1,574 individuals without pain (35.4%), 1,138 individuals with mild pain (25.6%), and 1,734 individuals with moderate/severe pain (39.0%). For the entire population and subjects in the premorbid‐stage subgroup, knee injury history, diabetes mellitus, depression, use of nonsteroidal anti‐inflammatory drugs (NSAIDs), and valgus malaligned knees were associated with more severe pain. Older age and stronger quadriceps muscles were associated with milder pain. As the disease progressed, the number of significant risk factors decreased. Only age and quadriceps muscle force remained significant in end‐stage disease.ConclusionMultiple factors are associated with pain in patients with knee OA. As the disease progresses, the number of significant risk factors gradually reduces. These findings suggest that strategies for managing pain related to knee OA should vary depending on radiographic grades.
Establishment of an allotetraploid fern species, Lepisorus yamaokae Seriz., between two highly niche‐differentiated parental species
Authors: Fujiwara Tao , Egashira Tsubasa , Gutiérrez‐Ortega José Said , Hori Kiyotaka , Ebihara Atsushi , Watano Yasuyuki 
Published: August 2022

AbstractPremiseThe successful establishment of polyploid species is hypothesized to be promoted by niche differentiation from the parental species or by range shifts during climate oscillations. However, few studies have considered both of these factors simultaneously. We resolved the origin of a tetraploid fern, Lepisorus yamaokae, and explored a pattern of niche differentiation among the allotetraploid and parental species in past and current climates.MethodsWe reconstructed phylogenetic trees based on plastid marker and single‐copy nuclear genes to resolve the allopolyploid origin of L. yamaokae. We also evaluated climatic niche differentiation among L. yamaokae and its two parental species using species distribution models in geographic space and principal component analysis.ResultsWe infer that L. yamaokae had a single allotetraploid origin from L. annuifrons and L. uchiyamae. Climatic niche analyses show that the parental species currently occupy different niche spaces. The predicted distribution of the parental species at the Last Glacial Maximum (LGM) suggests more opportunities for hybridization during the LGM or during other recent temporary range shifts. Lepisorus yamaokae has a narrower niche than the additive niche of the parental species. We also observed niche conservatism in L. yamaokae.ConclusionsRange shifts of the parental species during climatic oscillations in the Quaternary likely facilitated the formation and establishment of L. yamaokae. Further, the genetic intermediacy of L. yamaokae may have enabled a niche shift in its microenvironment, resulting in its successful establishment without a macroclimatic niche shift in L. yamaokae.
A novel pulmonary fibrosis murine model with immune‐related liver injury
Authors: Jia Kexin , Wu Jianzhi , Li Yijie , Liu Jia , Liu Runping , Cai Yajie , Zhang Yinhao , Li Xiaojiaoyang 
Published: August 2022

AbstractIdiopathic pulmonary fibrosis (IPF), characterized by aggravated alveolar destruction and fibrotic matrix deposition, tendentiously experiences the stage called acute exacerbation IPF (AE‐IPF) and progresses to multiple organ damage, especially liver injury. Recent studies have found a variety of immune microenvironment disorders associated with elevated IPF risk and secondary organ injury, whereas current animal models induced with bleomycin (BLM) could not completely reflect the pathological manifestations of AE‐IPF patients in clinic, and the exact underlying mechanisms are not yet fully explored. In the current study, we established an AE‐IPF model by tracheal administration of a single dose of BLM and then repeated administrations of lipopolysaccharide in mice. This mouse model successfully recapitulated the clinical features of AE‐IPF, including excessive intrapulmonary inflammation and fibrosis and extrapulmonary manifestations, as indicated by significant upregulation of Il6, Tnfa, Il1b, Tgfb, fibronectin, and Col1a1 in both lungs and liver and elevated serum aspartate transaminase and alanine transaminase levels. These effects might be attributed to the regulation of Th17 cells. By sharing this novel murine model, we expect to provide an appropriate experimental platform to investigate the pathogenesis of AE‐IPF coupled with liver injury and contribute to the discovery and development of targeted interventions.
Surface modification of UHMWPE fibers with chlorination and polydopamine for enhancing the mechanical properties of composites
Authors: Yuan Rui , Chu Zheng , Wu Xiaolian , Kong Fanmin , Jiang Guodong , Shen Yucai , Zhao Dong 
Published: August 2022

AbstractUltra‐high molecular weight polyethylene (UHMWPE) fibers had many excellent mechanical properties, but their applications in composites were limited due to the weak interfacial adhesion between UHMWPE fibers with non‐polar methylene and resin matrix. This paper explored an efficient method for the damage‐free modification of fibers by chloride grafting followed by polydopamine (PDA) deposition to obtain UHMWPE‐Cl‐PDA fiber while maintaining the excellent mechanical properties of the fiber. The chemical components of surface treated fibers were observed by XPS and FTIR‐ATR, and the results proved that the fiber surface has been successfully chlorinated and then coated with PDA layer. The surface morphologies of fibers measured by SEM showed the rough surface of UHMWPE‐Cl‐PDA fibers was beneficed to anchor the resin matrix. The different mechanical properties of composites were studied, such as interfacial shear strength (IFSS), impact strength, flexural strength and modulus, especially the IFSS between UHMWPE‐Cl‐PDA and epoxy matrix and the impact strength of UHMWPE‐Cl‐PDA composite were increased by 29.1% and 53.8%, respectively, compared with UHMWPE fibers deposited by PDA.
Preparation and evaluation of organosilica nanocapsules encapsulating DCOIT by using the response surface optimization
Authors: Liu Huatong , Lu Tao , Cheng Xueqing , Zhao Shigui , Zhou Chuanjian , Zhang Chen , Cheng Xiao 
Published: August 2022

AbstractAntifouling agent 4, 5‐dichloro‐2‐n‐octyl‐4‐isothiazolin‐3‐one (DCOIT) in a one‐stage process based on the self‐catalytic reaction between methyl trimethoxysilane (MTMS) and 3‐aminopropyl trimethoxysilane (APS) in an aqueous system without any surfactants and catalysts have been developed. The optimal preparation process parameters of organosilica nanocapsules encapsulating DCOIT (DCOIT@SiNC) were determined using response surface methodology (RSM) based on the single‐factor experimental results. The results of RSM optimization showed that 49.51% encapsulation efficiency (EE [%]) would be achieved with a shell–core mass ratio of 5.59:1, a MTMS‐APS mole ratio of 1.52:1, and a reaction temperature of 31°C. DCOIT@SiNC prepared according to the RSM optimal process exhibited a decent uniform sphericity with an average particle diameter of 660.50 nm. The encapsulation was characterized by Fourier‐transform infrared and X‐ray diffraction. The loading efficiency and thermal stability were verified via thermogravimetric analysis. Compared to DCOIT, DCOIT@SiNC had better controlled release performance, and the release kinetics investigated by Riger‐peppas model indicated that the release of DCOIT was diffusion‐controlled.
Munsell and Ostwald colour spaces: A comparison in the field of hair colouring
Authors: Liberini Simone , Rizzi Alessandro 
Published: August 2022

AbstractColour science has had a very long history, dotted over the millennia with many contributions from the most diverse fields of human knowledge. At the beginning of the 20th century, Albert Henry Munsell, an artist formally trained in academia, and Friedrich Wilhelm Ostwald, Nobel prize for chemistry in 1909 and amateur painter, each envisioned and developed a colour system with a related colour atlas. Both authors recognized the importance of the visual relationship between colours, which they conceived as sensations stemming from, but not merely confined to, pigments and light. We hereby describe the salient features of these colour spaces, their strengths and weaknesses, the authors' analogy of intents and divergence in execution. The contribution of this paper is a discussion on how these are employed both in Italian educational facilities, and salon practice, as well as a suggestion about their use within the industry of human hair cosmetics.
Multilevel security for medical image using heterogeneous chaotic map and deoxyribonucleic acid sequence operations
Authors: Akkasaligar Prema T. , Biradar Sumangala , Biradar Sunanda 
Published: August 2022

SummaryIn telemedicine and e‐health system, the medical images are transmitted through telecommunication. In telecommunication, medical images are transmitted through open source networks. The hackers can tamper or add noise to medical images. Diagnosing the correct disease from the altered medical images is highly impossible. Hence indulge with security, confidentiality and integrity for medical images. In this work, heterogeneous hyper chaotic maps, deoxyribonucleic acid (DNA) cryptography and SHA‐512 is proposed in a new multilevel cryptosystem. The multilevel permutation is performed using heterogeneous chaotic map and zigzag transform. The multilevel diffusion is performed using DNA multiplication and DNA ADD operation. To verify the integrity the SHA‐512 is employed. All DNA coding, and DNA decoding rules are employed dynamically to generate the encrypted medical image. The introduced multilevel cryptosystem provide better security analysis for medical image transmission. The proposed method is implemented in MATLAB software. The performance of proposed approach is associated with existing approaches in terms of evaluating parameters like NPCR (number of pixel changing rate), UACI (unified average changed intensity), correlation coefficient and time taken in seconds. Hence it proves the performance and efficiency of the proposed method are high as compared to the existing methods. The proposed approach also improves the security level and offers integrity and confidentiality, and provide better medical image for encryption with less time complexity.
Study of Calcium Signaling in Astrocytes with a Novel Endoplasmic Reticulum–Targeted GCaMP Sensor
Authors: Aryal Surya P. , Xia Mengfan , Ortinski Pavel I. , Richards Christopher I. 
Published: August 2022

AbstractThe endoplasmic reticulum (ER), the major organelle for the storage of Ca2+, maintains a concentration of Ca2+ much higher than in the cytosol or other subcellular organelles, such as the mitochondria. A variety of tools have been developed for measuring Ca2+ activity in neuronal and glial cells, but most of these sensors target either the plasma membrane (PM) or the cytosol. Though these sensors are important for measuring Ca2+ transients, they lack the capability to measure activity in the periphery of the ER or to measure low‐amplitude events resulting from Ca2+ exchange between the ER and other organelles, such as the mitochondria. We recently developed an ER‐targeted GCaMP6f anchored to the cytosolic side of the ER that can measure minute calcium exchange occurring in this region. In this article, we discuss detailed methods to characterize the ER‐GCaMP6f sensor, utilize it for calcium imaging in cultured astrocytes, and assess its expression and calcium imaging in astrocytes in rodent brains. © 2022 Wiley Periodicals LLC.Basic Protocol 1: Expression and characterization of ER‐GCaMP6fSupport Protocol 1: ER‐GCaMP6f‐expressing stable cell line generationBasic Protocol 2: In vitro calcium imaging with ER‐GCaMP6fSupport Protocol 2: Imaging of drug‐induced calcium activityAlternate Protocol 1: Transduction of astrocytes with ER‐GCaMP6f AAVAlternate Protocol 2: Calcium imaging of astrocytes with Fluo‐4 AMBasic Protocol 3: In vivo ER‐GCaMP6f expression and slice calcium imagingSupport Protocol 3: Pharmacological studies with 2‐APB in brain slices
Recent Progress on Phosphate Cathode Materials for Aqueous Zinc‐Ion Batteries
Authors: Ou Linna , Ou Huihuang , Qin Mulan , Liu Zhexuan , Fang Guozhao , Cao Xinxin , Liang Shuquan 
Published: August 2022

AbstractRechargeable zinc‐ion batteries (ZIBs) are attractive for large‐scale energy storage due to their superiority in resources, safety, and environmental friendliness. However, the lack of suitable ZIBs cathode materials limits their practical applications. In consideration of the excellent electrochemical performance of phosphate materials in monovalent ion (Li+, Na+) batteries, they were also employed as ZIBs cathode materials recently and performed well with high potential. But they also suffer from low capacity and poor conductivity, and the energy storage mechanism is not clear yet. This Review provides a state‐of‐the art overview on the developments of phosphate cathode materials in ZIBs, including NASICON‐type phosphates, fluorophosphates, olivine‐structured, layered‐structured, and novel‐structured phosphate materials mainly. This study presents the reaction mechanism and electrochemical performance of phosphate cathode materials in aqueous ZIBs, and future research directions are discussed, which are intended to provide guidance for exploring high‐potential cathode materials for ZIBs.
A novel model for detecting advanced fibrosis in patients with nonalcoholic fatty liver disease
Authors: Yang Xinyu , Xia Mingfeng , Chang Xinxia , Zhu Xiaopeng , Sun Xiaoyang , Yang Yinqiu , Wang Liu , Liu Qiling , Zhang Yuying , Xu Yanlan , Lin Huandong , Liu Lin , Yao Xiuzhong , Hu Xiqi , Gao Jian , Yan Hongmei , Gao Xin , Bian Hua 
Published: August 2022

AbstractAimsThe study aimed to develop a novel noninvasive model to detect advanced fibrosis based on routinely available clinical and laboratory tests.Materials and MethodsA total of 309 patients who underwent liver biopsy were randomly divided into the estimation group (n = 201) and validation group (n = 108). The model was developed using multiple regression analysis in the estimation group and further verified in the validation group. Diagnostic accuracy was evaluated using the receiver operating characteristic (ROC) curve.ResultsThe model was named NAFLD Fibrosis Index (NFI): −10.844 + 0.046 × age − 0.01 × platelet count + 0.19 × 2h postprandial plasma glucose (PG) + 0.294 × conjugated bilirubin − 0.015 × ALT + 0.039 × AST + 0.109 × total iron binding capacity −0.033 × parathyroid hormone (PTH). The area under the ROC curve (AUC) of NFI was 0.86 (95% CI: 0.79–0.93, p < 0.001) in the estimation group and 0.80 (95% CI: 0.69–0.91, p < 0.001) in the validation group, higher than NFS, FIB4, APRI, and BARD, and similar to FibroScan (NFI AUC = 0.77, 95% CI: 0.66–0.89, p = 0.001 vs. FibroScan AUC = 0.76, 95% CI: 0.62–0.90, p = 0.002). By applying the low cut‐off value (−2.756), advanced fibrosis could be excluded among 49.3% and 48% of patients in the estimation group (sensitivity: 93.1%, NPV: 97.9%, specificity: 55.2%, and PPV: 26.0%) and validation group (sensitivity: 81.3%, NPV: 94.2%, specificity: 53.3%, and PPV: 23.2%), respectively, allowing them to avoid liver biopsy.ConclusionsThe study has established a novel model for advanced fibrosis, the diagnostic accuracy of which is superior to the current clinical scoring systems and is similar to FibroScan.