bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does Age Affect the Outcomes of Core Decompression for the Treatment of Kienböck Disease?
Authors: MANIGLIO Mauro , ZAIDENBERG Ezequiel E. , THÜRIG Gregoire , GAUTIER Emanuel , BORETTO Jorge G. , DE CARLI Pablo 
Published: January 2022

Background: Core decompression of the distal radius is a minimally invasive technique that has demonstrated good clinical outcomes in the treatment of Kienböck disease. However, the effectiveness of core decompression has not been compared in different age groups. The aim of this study is to compare the outcomes of core decompression in patients <45 years of age to those ≥45 years of age. Methods: This retrospective study included 36 patients with Kienböck disease who were treated with core decompression over a 20-year period. The mean follow-up was 7 years. Outcome measures included visual analogue scale pain score (VAS), active range of flexion/extension at the wrist, grip strength, and modified Mayo wrist score. The patients were divided into two age groups namely <45 years (younger group; n = 22) and ≥45 years (older group; n = 12) and the outcome measures were compared between the two age groups. Results: There were no statistically significant differences between the outcomes of the two age groups. Conclusion: The outcomes of core decompression of the distal radius for Kienböck disease in older patients (≥45 years) are favorable and similar to those seen in younger patients (<45 years). Level of Evidence: Level III (Therapeutic)
An Anatomical Study of the Palmaris Brevis, Transverse Carpal Ligament, and the Recurrent Motor Branch of the Median Nerve
Authors: NAM Yong Seok , HONG EunAh , KIM BumSik , YOON JungSoo , LIM SooA , HAN YeaSik , EO SuRak 
Published: January 2022

Background: The anatomical structures in relation to the carpal tunnel release are the palmaris brevis muscle (PBM), transverse carpal ligament (TCL), and the recurrent motor branch of the median nerve (RMBMN). Our aim is to describe the gross morphology in the Korean population of the PBM, TCL, and RMBMN specifically looking for anomalies, and to determine the muscles encountered during a standard carpal tunnel release. Material and Methods: A total of 30 cadaveric hands were dissected. A longitudinal line drawn from the third web space to the midpoint of the distal wrist crease served as the reference line (RL). The PBM and TCL were classified according to its shape and location. The length, width, and thickness of the TCL were measured. The ratio of the lengths of PBM and TCL to RL was calculated. The course of the RMBMN was dissected specifically looking for anomalies. We also looked at the muscle fibers encountered during a standard carpal tunnel release to identify the muscle. Results: PBM was classified into three different types based on the shape. The average thickness of the PBM and TCL were 0.89 ± 0.16 mm and 1.43 ± 0.40 mm, respectively. The distal border of the TCL was thicker than the proximal border. The average ratio of the length of the PBM to the RL was 25.65 ± 8.62% and TCL to the RL was 24.00 ± 3.37%. The distribution of the RMBMN was classified into three different types. A few accessory branches of the RMBMN were also noted. And 36 muscle fibers were noted within the TCL in line with the RL. Conclusion: We clarified findings and added quantitative information about the anatomical structures surrounding carpal tunnel. A thorough knowledge of the anatomy and anomalies around the carpal tunnel is helpful for surgeons to ensure optimal surgical results.
New peri-Gondwanan occurrences of the Ordovician genus
Diamphidiocystis
(Echinodermata, Stylophora): implications for mitrocystitid palaeobiogeography and diversity
Authors: Lefebvre Bertrand , Nohejlová Martina , Kašička Libor , Zicha Ondřej 
Published: January 2022

Abstract

Anomalocystitid mitrates represent one of the most diverse and long ranging clade of stylophorans (Early Ordovician–Middle Devonian). Although they probably originated from a peri-Gondwanan stock of early mitrocystitids during the Floian, the fossil record of anomalocystitids in the Middle–Upper Ordovician of the Mediterranean Province remains extremely scarce and largely underestimated. The unusually shaped anomalocystitid genus
Diamphidiocystis
was originally described in the latest Katian–Hirnantian of North America (Illinois). However, earlier occurrences of this genus in the late Darriwilian of western France (Brittany) suggest a probable peri-Gondwanan origin. Based on new Middle to Late Ordovician material from the Anti-Atlas (Morocco), Bohemia (Czech Republic) and Brittany (France), all occurrences of Mediterranean
Diamphidiocystis
are considered as conspecific and formally described as
D. regnaulti
sp. nov. The palaeobiogeographical significance of Ordovician anomalocystitid mitrates is discussed.
Florescer o Eu na pele
Authors: Rodarte André Kupfermann , Carvalho Thaísa , Marcelino Rosilene 
Published: January 2022

Este artigo propõe uma discussão acerca das intervenções no corpo humano pela perspectiva do consumo, comunicação e psicanálise. Como objeto de estudo, as tatuagens são fenômenos férteis para pensar limites e configurações de regimes de visibilidade contemporâneos. Em particular, investigaremos intervenções estéticas em cicatrizes como tentativas de ressignificação e expressão corporal através do programa BBC Three: A Tattoo To Change Your Life. A produção de novos sentidos através de tais inscrições na pele manifesta a celebração de um compromisso moral de um dever-ser, fundamentado na condição corpórea como subterfúgio para construção e reconhecimento de subjetividades.
Espiritismo e humor no Youtube: dinâmicas de comunicação religiosa do canal Amigos da Luz
Authors: Almeida Alanne , Nascimento Robéria 
Published: January 2022

Este artigo deriva de uma pesquisa em curso[1] que investiga os mecanismos de humor adotados pelo Canal Amigos da Luz na comunicação do Espiritismo via plataforma do Youtube. A empatia do riso decorre da junção entre dramaturgia e comédia trazendo novos contornos à relação mídia e religiosidades conforme o paradigma da midiatização (FAUSTO NETO, 2008; MARTINO, 2016). Do ponto de vista metodológico uma análise narrativa (MOTTA, 2013) observa os esquetes para verificar a adoção da paródia em torno do segmento filosófico-religioso. Resultados preliminares sobre os comentários dos usuários indicam que a estratégia da comicidade tem favorecido o entendimento dos conceitos espíritas.

[1] Intitulada “Fronteiras da paródia e do riso: sentidos de midiatização religiosa do Canal Amigos da Luz”.
O início da publicidade em Barbacena (MG) uma análise das publicidades veiculadas no jornal O Parahybuna em 1837
Authors: Rosa Márcio Ribeiro Ferreira , Rios Ricardo Matos de Araújo 
Published: January 2022

A presente obra analisa as campanhas públicitarias do extinto jornal impresso 'O Parahbuna' de Barbacena Minas Gerais.
O presente artigo tem o objetivo de mapear e compreender as primeiras peças publicitárias veiculadas na imprensa de Barbacena (MG), inseridas no jornal O Parahybuna, em 1837. Este foi o primeiro periódico da cidade e, mesmo de duração efêmera, trata-se de importante documento histórico para compreender a publicidade na cidade. O interesse da pesquisa está em mapear e descrever as peças comerciais presentes no jornal O Parahybuna em 1837 e analisar os consequentes locus sociais, em uma dimensão sociohistórica. O percurso teórico está alicerçado nos conceitos de ethos para Amossy (2008) e Charaudeau (2008). Paralelamente, investiga-se a questão estética da publicidade brasileira no Século XIX.
Radiojornalismo diário em formato podcast
Authors: Winter Yasmin Lisboa , Feital Yasmine , Machado Felipe Viero Kolinski 
Published: January 2022

O presente artigo se propõe a estudar os podcasts jornalísticos Durma com essa e El primer café, com base em 8 episódios e um especial divulgados na última semana do mês de agosto de 2019. É feita uma análise descritiva de forma a entender como os dois objetos, mesmo com suas singularidades, se constituem como podcasts jornalísticos diários. Além disso, é pensado como o formato podcast tem crescido de forma a diversificar as estruturas de produção e distribuição da informação, a fim de um maior alcance e aproximação com o/a ouvinte. Essas questões são trabalhadas através dos conceitos principais de jornalismo como atribuição de sentido e a polifonia, além de radiojornalismo e podcast como uma nova forma de interação sonora.
Impasses da democracia na América Latina
Authors: Forgerini Fernanda Oliveira 
Published: January 2022

O presente artigo propõe uma análise dos discursos circulantes (CHARAUDEAU, 2018) acerca dos discursos sobre limites da democracia e da liberdade de expressão em matérias jornalísticas publicadas na Folha de S. Paulo, O Globo e o Estado de S. Paulo a propósito das manifestações no Chile em outubro de 2019. Para isso, buscamos apreender traços de dialogismo e polifonia (GRILLO, 2005) presentes nos textos analisada. A partir de rastreamentos junto aos acervos digitais dos veículos em foco, o corpus de pesquisa se constitui de reportagens estampadas nas capas dos periódicos no período de oito dias subsequentes à determinação do estado de exceção no país pelo presidente Sebastián Piñera.
Batalha de Gustavo Dahl pela ANCINE (1998 – 2006)
Authors: Ponce Davi Tadeu Francisco 
Published: January 2022

Desde 2016, a Ancine – Agência Nacional do Cinema – vem tendo o seu funcionamento e atividades questionados por órgãos do governo federal: o fomento à produção cinematográfica no Brasil e a sua exibição. Procuramos, neste artigo, investigar as formas encetadas por Gustavo Dahl – cineasta, e gestor do cinema brasileiro - para a sua criação e manutenção até o presente. Portanto, pretende-se observar a atuação e importância dele no período de Retomada do Cinema Brasileiro (1994-2001), desde o seu projeto inicial para a ANCINE até o que ela viria a tornar-se. Para isso, abordaremos a trajetória de Dahl no meio cinematográfico; o cenário cinematográfico entre 1990 a 2001; uma problematização do período em que Dahl foi diretor-presidente da agência (2001-2006); e o que se pode observar dos resultados concretos da criação da ANCINE e a situação em que se encontra em 2020.
A importância da mídia impressa na gestação do nacionalismo palestino pré-1948
Authors: Baldin Vitoria Paschoal 
Published: January 2022

Este trabalho pretende apresentar e analisar, a partir de revisão bibliográfica, a importância da mídia imprensa no desenvolvimento do nacionalismo palestino entre o final do Império Otomano até a fundação do Estado de Israel. Argumenta-se que os jornais e outros sistemas de publicação financiados por famílias nobres locais auxiliou na gestação e disseminação de sentimentos nacionalistas na população. A partir disso, movimentos populares de amplo alcance, como a revolta árabe de 1936, foram possíveis e criaram-se bases para a consolidação nesses imaginários após os eventos de 1948. Dessa maneira, há expressões do nacionalismo palestino anterior à formação do Estado de Israel, em que a mídia teve papel central nesse processo.
O uso de tipografias baseadas em pixações no design: entre dissenso e consenso
Authors: Porto João Augusto 
Published: January 2022

O objetivo deste artigo é descrever as dinâmicas que envolvem o uso de elementos de grafite e pixo no design comercial, neste caso as tipografias desenvolvidas em alusão às letras usadas em pixações urbanas. Considerando fenômenos de apropriação presente na sociedade neoliberal, vemos um modo de comodificação da cultura de rua, que visa trazer um aspecto inovador para a concepção de peças, enquanto a pixação ainda é criminalizada, e tem seu espaço como expressão dentro das cidades penalizado. Ao apresentar este tema dentro de seu contexto político em que a estrutura da sociedade reprime a pixação, mas seu uso no design é estimulado por trazer um caráter urbano, de transgressão, de movimento e de juventude à peça ou produto.
PALAVRAS-CHAVE: pixação; design; apropriação; tipografia; comodificação;
First Observations of Mesospheric OH Emission Profiles from OMPS/LP
Authors: Chen Zhong 
Published: January 2022

Abstract
The hydroxyl radical (OH) is one of the most reactive trace species and plays several important roles in the photochemical equilibrium and energy balance in the mesosphere. Global observations of OH from satellite instruments have a role to play in the study of OH and water vapor variations. This study describes an advanced algorithm to detect mesospheric OH emission profiles from the Suomi NPP satellite Ozone Mapping and Profiler Suite Limb Profiler (OMPS/LP). A triplet technique has been adapted to the OMPS/LP radiance measurements for determining OH emission signatures and OH index (OHI) from the OH A2Σ+-X2Π 0-0 band near the 308.8-nm wavelength. The derived mesospheric profiles provide an overall picture of the vertical distribution of OHI between 55 and 84 km and seasonal and latitudinal variability of the strength and height of the OHI. The observed annual cycle is correlated with the water vapor cycle and anticorrelated with the mesospheric temperature cycle. The data show that the relationships persist during the period of April 2012–December 2020. The seasonal behavior of OHI may be associated with variations in solar illumination or mesospheric water vapor abundance. The influence of solar illumination is dominant in the midlatitudes, while the OHI pattern is dominated by water vapor photolysis and other influences in the tropics.
Evaluation of hydromechanical and functional properties of diversion-type microcapsule-suspension bioreactor for bioartificial liver
Authors: Lu Juan , Zhu Danhua , Li Lanjuan 
Published: January 2022

Aim: To evaluate the performance of a diversion-type microcapsulesuspension fluidized bed bioreactor and a choanoid fluidized bed bioreactor as bioartificial liver support systems. Materials and methods: We evaluated the performance between the modified fluidized bed bioreactor based on diversion-type microcapsule suspension (DMFBB) and choanoid fluidized bed bioreactor (CFBB). The fluidization performance, fluidized height, bed expansion, and the mechanical stability and strength of microcapsule were determined. The viability, synthetic, metabolism, and apoptosis of microcapsulated HepLi5 cells were evaluated. Finally, samples were collected for measurement of alanine aminotransferase, total bilirubin, direct bilirubin, and albumin concentrations. Results: Uniform fluidization was established in both DMFBB and CFBB. The bed expansion, shear force, retention rate, swelling rate, and breakage rate of microcapsules differed significantly between two bioreactors over 3 days. The viability of microencapsulated HepLi5 cells and the activities of cytochrome P450 1A2 and 3A4 increased on each day in DMFBB compared to the control. The albumin and urea concentrations in the DMFBB displayed obvious improvements compared to the control. Caspase3/7 activities in the DMFBB decreased compared to those in the CFBB. At 24 h, the alanine aminotransferase concentration in the DMFBB declined significantly compared to the control. The total and direct bilirubin concentrations within plasma perfusion were decreased and albumin was increased in the DMFBB at 24 h than in the CFBB. Conclusion: The DMFBB shows a promising alternative bioreactor for use in bioartificial liver support systems for application of clinical practice.
Immediate severe hypersensitivity reaction to etoposide phosphate: Case report and review of the literature
Authors: Pringle Nicole R , Gilbar Peter J , Grewal Guranjan D 
Published: January 2022

Introduction Hypersensitivity reactions from intravenous (IV) etoposide have been rarely reported, with these being seen more commonly with etoposide than with etoposide phosphate. This is generally explained by the need for polysorbate 80, a known cause of hypersensitivity, as a solubiliser, in the etoposide formulation. Case report We report a 22-year-old male, being treated with adjuvant BEP (bleomycin/etoposide phosphate/cisplatin) for a testicular germ cell tumour. Bleomycin and cisplatin were administered without incident. Within one minute of etoposide phosphate commencement he experienced a severe hypersensitivity reaction, consisting of widespread erythematous rash, facial swelling, and nausea. Observations included unrecordable blood pressure, tachycardia, hypoxia, and loss of consciousness, confirming a diagnosis of anaphylactic shock. Management and outcome Etoposide phosphate was ceased immediately. He was successfully managed with IV hydrocortisone, IV promethazine, intramuscular adrenaline, IV fluids and oxygen. Following admission for observation, significant improvement occurred over 48 h. Discussion Hypersensitivity reactions to etoposide were first reported in the 1980s. Following reactions to etoposide, substituting etoposide phosphate into chemotherapy regimens has commonly allowed treatment to continue without incidence. Anaphylactic reactions to etoposide phosphate were first documented in 2012, with further cases reported subsequently. Unlike etoposide, etoposide phosphate is highly soluble in aqueous solutions and doesn't require adjuvants in the formulation. Hypersensitivity reactions to etoposide phosphate are therefore likely related to the etoposide drug molecule itself. Clinicians should be aware of this rare, but potentially life-threatening, toxicity when using etoposide-based treatments and have procedures in place to urgently manage any hypersensitivity reactions that may occur.
Azacitidine-induced massive pericardial effusion in a child with myelodysplastic syndrome
Authors: Fogaça da Mata Miguel , Vieira Martins Miguel , Rato João , Madeira Márcio , Gonçalves Jean-Pierre , Teixeira Ana , Anjos Rui 
Published: January 2022

Introduction Pericardial effusions are rare yet potentially fatal conditions in children. Azacitidine is a DNA-hypomethylating agent used in the treatment of myelodysplastic syndrome. Although seldomly described in adults, no cases of azacitidine-induced pericardial effusion have been reported in children. Case report A 7-year-old boy with myelodysplastic syndrome presented with a large pericardial effusion with risk for cardiac tamponade after his first azacitidine cycle. Management & outcome The patient was admitted to a pediatric ICU, antibiotic and steroid therapy were initiated. Pericardiocentesis was done due to hemodynamic instability. Serum and pericardial fluid complementary evaluation excluded infectious and malignant causes. The pericardial effusion did not reappear and additional pleural and ascitic slight effusions responded well to diuretics. Follow-up azacitidine cycles were administered by tapering daily dosages and using adjunctive steroid therapy, with no additional adverse events. Discussion We report the first pediatric case of large pericardial effusion secondary to azacitidine therapy in a child with MDS. This adverse reaction has not been described in pediatric patients, in which this therapeutic option has been increasingly used. We seek to raise awareness on the potential life-threatening cardiotoxicity of azacitidine in pediatric patients.
Multiple rechallenges with anti-PD-1 immunotherapy in patients with checkpoint inhibitor-related pneumonitis: A report of two cases
Authors: Yan Zheng , Yao Shuna , Yuan Junhui , Liu Yanyan , Yao Zhihua 
Published: January 2022

Introduction With the expanding use of immune checkpoint inhibitors (ICIs) in patients with various types of cancers, many more patients are experiencing checkpoint inhibitor-related pneumonitis (CIP). After recovery from CIP, some patients are rechallenged with ICI therapy. The CIP will recur in a considerable proportion of rechallenged patients. When severe or recurrent CIP (rCIP) occurs, ICI therapy is usually terminated, resulting to treatment failure and tumour progression. The feasibility of multiple rechallenges with immunotherapy in patients with rCIP is unknow. Case presentation Two patients with refractory classical Hodgkin lymphoma (cHL) were treated with anti-programmed cell death protein 1 (PD-1) immunotherapy. The lymphoma responded well to the ICI therapy, but both patients experienced CIP. The immunotherapy was suspended and steroid was introduced to treated the CIP. When the CIP resolved, however, the lymphoma progressed. Management and outcome The patients were rechallenged with anti-PD-1 immunotherapy in the absence of alternative treatment options. The lymphoma responded again, but the CIP recurred. The immunotherapy was suspended again and steroid was reintroduced. These episodes repeated multiple times. At the time of submission of this manuscript, the tumour in both patients has been controlled for more than 4 years, and the immunotherapy is still continuing. Conclusion Multiple rechallenges with immunotherapy is feasible in selected patients with rCIP.
Evaluation of awareness about importance of high fever in leukemia and lymphoma patients receiving chemotherapy among healthcare professionals working in pharmacies other than hospital pharmacies: A survey from a Central Anatolian city
Authors: Mert Duygu , Merdin Alparslan 
Published: January 2022

Introduction Pharmacy staff are part of the healthcare delivery. In some cases, the patient goes to the pharmacy before the doctor and asks for a medicine suitable for his own complaint. The aim of this study is to evaluate the awareness about the importance of high fever in patients with leukemia and lymphoma receiving chemotherapy among healthcare professionals working in non-hospital pharmacies. Material and method The study is a survey study. 140 pharmacy employees working in non-hospital pharmacies in Ankara Province were included in the study. Volunteer participants were included in the study. Seven questions were asked to the participants. Results About 47.1% of the participants stated that they would advise patients to go immediately to the nearest hospital's emergency department when they presented to the pharmacy and said that they had high fever. It was stated by 56.5% of the participating pharmacy employees that high fever did not pose the same risk for a leukemia or lymphoma patient receiving chemotherapy as it did for a leukemia or lymphoma patient not receiving chemotherapy. Conclusion In this study, it was found that awareness about importance of high fever in leukemia and lymphoma patients receiving chemotherapy among healthcare professionals working in pharmacies other than hospital pharmacies was not very high. Providing necessary information to the pharmacy personnels and increasing the awareness about importance of high fever in leukemia and lymphoma patients receiving chemotherapy among the non-hospital pharmacy staff might also contribute to the reduction of negativities associated with infections in such patients.