bluuebunny/crossref_metadata_2025_split huggingface dataset:
Managing production and inventory in a remanufacturing supply chain with two classes of cores under consignment stock agreement
Authors: Zhu Xiaoyan , Zhang Ting , Cao Yunzhi 
Published: July 2022

AbstractThis paper addresses the production scheduling and inventory management in a closed‐loop supply chain that recycles both high‐quality and low‐quality cores and makes products using cores and new raw materials. The manufacturing/remanufacturing supply chain consists of a vendor and a buyer, and they collaborate under a consignment stock (CS) agreement. We investigate and compare three operation policies under the CS agreement, covering continuous and intermittent production manners and shipments of equal and unequal batch sizes. For each operation policy, we develop a mixed integer nonlinear programming model to jointly optimize the production sequence of two classes of cores, production cycle length, shipment frequency, and shipment batch sizes, with the objective of minimizing the cost rate. By analyzing the respective decisions and conducting an extensive numerical study with various scenarios, we explore the advantages and applications of each operation policy. Based on our research findings, we provide general guidelines and criteria for operation policy selection.
Consolidation and high‐temperature properties of ceramics in the TaC–NbC system
Authors: Demirskyi Dmytro , Nishimura T. , Suzuki T. S. , Yoshimi K. , Vasylkiv Oleg 
Published: July 2022

AbstractIn this study, we explored the consolidation, solid‐solution formation, and high‐temperature properties of carbides in the Ta–Nb–C system. The tantalum niobium carbide bulks can be consolidated by spark‐plasma sintering only at a temperature of 2200°C using a 30‐min dwell. The ceramics were homogeneous solid solutions and a linear dependence of the lattice parameters on the NbC content was observed. The average grain size varied between 10 and 30 μm, while the reference monolithic tantalum carbide consolidated under similar conditions had a grain size exceeding 40 μm. The room temperature strength linearly decreased from TaC to NbC. The 75 mol% NbC ceramic showed almost an unchanged strength up to 1600°C (450 ± 20 MPa), following the linear decrease in strength to 290 MPa at 2000°C. The monolithic tantalum carbide had showed the lowest strength at 2000°C among the studied ceramics.
Making small molecules in plants: A chassis for synthetic biology‐based production of plant natural products
Authors: Liu Xinyu , Zhang Peijun , Zhao Qiao , Huang Ancheng C. 
Published: July 2022

AbstractPlant natural products have been extensively exploited in food, medicine, flavor, cosmetic, renewable fuel, and other industrial sectors. Synthetic biology has recently emerged as a promising means for the cost‐effective and sustainable production of natural products. Compared with engineering microbes for the production of plant natural products, the potential of plants as chassis for producing these compounds is underestimated, largely due to challenges encountered in engineering plants. Knowledge in plant engineering is instrumental for enabling the effective and efficient production of valuable phytochemicals in plants, and also paves the way for a more sustainable future agriculture. In this manuscript, we briefly recap the biosynthesis of plant natural products, focusing primarily on industrially important terpenoids, alkaloids, and phenylpropanoids. We further summarize the plant hosts and strategies that have been used to engineer the production of natural products. The challenges and opportunities of using plant synthetic biology to achieve rapid and scalable production of high‐value plant natural products are also discussed.
Three populisms and two dead ends: Variants of agrarian populism in Thailand
Authors: Pye Oliver , Chatuthai Nantawat 
Published: July 2022

AbstractThis article discusses three forms of agrarian populism in Thailand: the “grassroots populism” of the Assembly of the Poor, the “reactionary populism” of the yellow shirts, and the “capitalist populism” of the red shirts. We examine how these three strands of populism are embedded within dynamics of agrarian change in Thailand and how the intellectual and activist orientation towards agrarian populism led to the neglect of labour, particularly agricultural migrant workers. We show how key ideological underpinnings of the Assembly's grassroots populism (Brass's “agrarian myth”) could be appropriated for the agrarian component of both reactionary and capitalist populism. Rather than a new populism, we argue that a broad and popular challenge to right‐wing authoritarianism should develop inclusive class politics that embrace the rural–urban linkages that already define the social fabric of the new, rural, and agrarian precarious working class.
Efficacy and tolerability of a novel skin cream for improving periocular rhytids and dryness
Authors: Calkin Jacqueline M. , Boudreaux Alison A. , Taylor Barbara 
Published: July 2022

AbstractObjectiveA novel topical cream was developed to address the appearance of aging periorbital skin. The goal of this study was to evaluate the efficacy and tolerability of this product (Total Eye® Firm & Repair Cream; Colorescience, Inc., Carlsbad, CA) for improving periorbital wrinkles, dryness, laxity, and dark circles.MethodsThis 8‐week open‐label trial enrolled subjects 35–65 years old seeking periocular rejuvenation (N = 25; 22 female, 3 male). The product was applied each morning and evening after facial cleansing. Study endpoints were changes in Investigator Clinical Grading and Eye Appearance Assessments, Subject Self‐assessment Questionnaires, and tolerability after 4 and 8 weeks of treatment.ResultsAmong subjects completing the study (n = 23), all (100%) showed some global improvement at Weeks 4 and 8 and almost half (48%) achieved moderate or marked improvement. Improvements were observed for all parameters and were most pronounced for wrinkles, laxity, and dark circles. Improvements for laxity and dryness were significant by Week 4 and for dark circles by Week 8. At Week 8, subjects agreed or strongly agreed that the product made their eyes feel more hydrated (100%), look and feel healthier (95%), and increased confidence in their eye appearance (91%). The product was well‐tolerated.LimitationsModest number of subjects and open‐label study design.ConclusionTwice‐daily Total Eye® Firm & Repair Cream improved the overall appearance of the periorbital area. The product was well‐tolerated and most treated subjects were satisfied with their results. The product is a viable option for treating periorbital wrinkles and laxity and should be considered a safe and effective skincare option.
Tracking and recording the lip dynamics for the integration of a dynamic virtual patient: A novel dental technique
Authors: Revilla‐León Marta , Zeitler Jonathan M. , Blanco‐Fernández Daniel , Kois John C. , Att Wael 
Published: July 2022

AbstractA step‐by‐step technique is described for tracking and recording, in real time, the lip dynamics of a patient and integrating them into a 3D virtual patient representation using facial trackers and motion engine software programs. The main advantage of this technique is that it enables capturing of the lip movements of the patient in real time; therefore, the lip movements are not simulated from a previously recorded video of the patient using animation software programs.
Correlates of sexual harassment victimization among adolescents: A scoping review
Authors: Bolduc Marie‐Louise , Martin‐Storey Alexa , Paquette Geneviève 
Published: July 2022

AbstractSexual harassment (SH) is an important public health problem among adolescents and is associated with negative outcomes. Using a theory‐based, developmentally‐informed approach, this scoping review focuses on SH victimization among adolescents (number of studies included = 20) and aims to (1) examine how the extant literature on correlates of SH defined and measured SH, and (2) identify correlates associated with SH victimization among adolescents, focusing particularly on differences between boys and girls. For the first objective, results showed variations in the definition of SH used, with very few studies employing validated measures of SH. For the second objective, the most frequently examined and supported correlates were those stemming from transactional models. Important gender differences in correlates emerged between boys and girls. Among girls' previous victimization experiences emerged as the most consistent correlates of SH, while among boys, adherence to gender role norms and beliefs and higher perception of personal power were most consistently associated with higher SH victimization. Prevention of SH needs to include youth, teachers, and parents as the results show the influence of all these social contexts in SH victimization. These prevention efforts should target groups at higher risk of SH, such as sexual and gender minority youth.
Bacterial exudates as growth‐promoting agents for the cultivation of commercially relevant marine microalgal strains
Authors: Sauvage Justine , Wikfors Gary H. , Dixon Mark S. , Kapareiko Diane , Sabbe Koen , Li Xiaoxu , Joyce Alyssa 
Published: July 2022

AbstractIn laboratory and industrial cultivation of marine microalgae, it is customary to enrich cultures with macronutrients (N, P), chelated trace metals, and vitamins at ~104× concentrations found in nature to obtain high culture densities. Other naturally occurring growth‐promoting compounds found in local seawater are not enriched and remain at environmental concentrations. Microalgae may thus be deprived of the mutualistic contributions of co‐occurring microorganisms with which they have evolved complex chemical relationships. In the present study, we assess the direct (mixed bacteria–microalgae cultivation) and indirect (exposure to exudates only, without physical contact) effects of 10 bacterial strains on the growth of five marine microalgal strains used as feeds in marine aquaculture hatcheries. Bacterial strains were selected based upon previously reported growth‐promoting characteristics in plants or microalgae, or known release of probiotics. Our experiments demonstrate superior stimulation of microalgal growth by bacterial exudates, and without the presence of the bacteria that produced these exudates. However, response to bacterial exudate enrichment was dependent upon the microalgae strain and bacterial pairing. Exudates fromBacillus,Mesorhizobium, andPhaeobacterstrains were most effective, with 22%–69% increases in microalgal specific growth rate. Such findings indicate that bacterial exudates accelerate rate‐limiting processes governing nutrient acquisition, assimilation, or anabolism, and possibly algal release of exopolymeric substances. Maximal cell density, however, remained constrained by macronutrient limitation. Scaled‐up trials in an oyster hatchery confirmed the practical benefit of bacterial exudate culture medium enrichment and demonstrated the suitability of exudate‐enriched microalgae to feed hatchery‐reared bay scallops. This work presents a promising strategy to improve microalgal culture media formulations using bacterial exudate components as growth promoters, and is the first such study to identify specific pairings with relevance for aquaculture production.
Becoming breastfeeding friendly in Great Britain—Does implementation science work?
Authors: Kendall Sally , Merritt Rowena , Eida Tamsyn , Pérez‐Escamilla Rafael 
Published: July 2022

AbstractThe Becoming Breastfeeding Friendly (BBF) in Great Britain study was conducted during 2017–2019 comprising three country studies: BBF England, Wales and Scotland. It was part of an international project being coordinated during the same period by the Yale School of Public Health across five world regions to inform countries and guide policies to improve the environment for the promotion, protection and support of breastfeeding. This paper reports on the application of the BBF process that is based on an implementation science approach, across the countries that constitute Great Britain (England, Wales and Scotland). The process involves assessing 54 benchmarks across eight interlocking gears that drive a country's ‘engine’ towards a sustainable policy approach to supporting, promoting and protecting breastfeeding. It takes a consensus‐oriented approach to the evaluation of benchmarks and the development of recommendations. This paper provides a critical overview of how the process was conducted, the findings and recommendations that emerged and how these were managed. We draw on critical theory as a theoretical framework for explaining the different outcomes for each country and some considerations for future action.
The pH sensor and ion binding of NhaD Na+/H+ antiporter from IT superfamily
Authors: Lv Peiwen , Li Yaru , Wang Ruimin , Zhang Ye , Wang Wenkai , Liu Yuanxiang , Shang Yan , Su Dandan , Wang Wei , Yang Chunyu 
Published: July 2022

AbstractSodium‐proton (Na+/H+) antiporters from the ion transporter (IT) superfamily play a vital role in controlling the pH and electrolyte homeostasis. However, very limited information regarding their structural functions is available to date. In this study, the structural model of the NhaD antiporter was proposed as a typical hairpin structure of IT proteins, with two symmetrically conserved scaffold domains that frame the core substrate‐binding sites, and four motifs were identified. Furthermore, 25 conserved sites involving these domains were subjected to site‐directed mutagenesis, and all mutations resulted in an impact on transport abilities. In particular, as candidates for Na+‐binding sites, D166 and D405 mutations at hairpin discontinuities were detrimental to transport activities and were found to induce pronounced conformational changes using fluorescence resonance energy transfer (FRET) assays. In addition, as observed in the NhaA structure, some charged residues, for example, E64, E65, R454, and R464, are predicted to be involved in the net charge switch of NhaD activation, by collectively form a “pH sensor” at the entrance of the cytoplasmic funnel. Mutations encompassing these residues were detrimental to the transport activity of NhaD or lost the capacity to respond to pH signals and trigger conformational changes for Na+ translocation.
Valsa mali secretes an effector protein VmEP1 to target a K homology domain‐containing protein for virulence in apple
Authors: Wang Weidong , Wang Shuaile , Gong Wan , Lv Luqiong , Xu Liangsheng , Nie Jiajun , Huang Lili 
Published: July 2022

AbstractThe K homology (KH) repeat is an RNA‐binding motif that exists in various proteins, some of which participate in plant growth. However, the function of KH domain‐containing proteins in plant defence is still unclear. In this study, we found that a KH domain‐containing protein in apple (Malus domestica), HEN4‐like (MdKRBP4), is involved in the plant immune response. Silencing of MdKRBP4 compromised reactive oxygen species (ROS) production and enhanced the susceptibility of apple to Valsa mali, whereas transient overexpression of MdKRBP4 stimulated ROS accumulation in apple leaves, indicating that MdKRBP4 is a positive immune regulator. Additionally, MdKRBP4 was proven to interact with the VmEP1 effector secreted by V. mali, which led to decreased accumulation of MdKRBP4. Coexpression of MdKRBP4 with VmEP1 inhibited cell death and ROS production induced by MdKRBP4 in Nicotiana benthamiana. These results indicate that MdKRBP4 functions as a novel positive regulatory factor in plant immunity in M. domestica and is a virulence target of the V. mali effector VmEP1.
Field evidence for litter and self‐DNA inhibitory effects on Alnus glutinosa roots
Authors: Bonanomi Giuliano , Zotti Maurizio , Idbella Mohamed , Termolino Pasquale , De Micco Veronica , Mazzoleni Stefano 
Published: July 2022

Summary

Litter decomposition releases nutrients beneficial to plants but also induces phytotoxicity. Phytotoxicity can result from either labile allelopathic compounds or species specific and caused by conspecific DNA. Aquatic plants in flowing water generally do not suffer phytotoxicity because litter is regularly removed. In stagnant water or in litter packs an impact on root functionality can occur. So far, studies on water plant roots have been carried out in laboratory and never in field conditions.

The effect of conspecific vs heterospecific litter and purified DNA were assessed on aquatic roots of the riparian woody species Alnus glutinosa L. using a novel method, using closed and open plastic tubes fixed to single roots in the field with closed tubes analogous to stagnant water. Four fresh and four decomposed litter types were used and analysed on extractable C, cellulose, lignin, N content and using 13C‐CPMAS NMR spectroscopy.

Inhibitory effects were observed with fresh litter in closed systems, with a positive correlation with extractable C and negative with lignin and lignin : N ratio. Alnus self‐DNA, but not heterologous one, caused acute toxic effects in the closed system.

Our results demonstrate the first field‐based evidence for self‐DNA inhibition as causal factor of negative feedback between plants and substrate.
‘It's like, instant respect’: Coworking spaces as identity anchoring environments in the new economy
Authors: Bacevice Peter A. , Spreitzer Gretchen M. 
Published: July 2022

AbstractAs employment relationships become more tenuous, as work grows increasingly virtual and as professional reputations circulate across online platforms, coworking provides individuals across various work arrangements with shared workspaces oriented towards sociability, visibility and convenience. Our study explores how coworking spaces also enable individuals to shape their professional identities while providing other important attributes of work to help it feel embodied and grounded. Drawing from interviews and surveys of members of a large coworking chain across the United States, we find that coworking spaces serve as identity anchoring environments. We find that many workers use material elements of the space to ground their professional identities in three ways: evidencing professional credibility, enacting a common ethos and energising connections with others. More broadly, we also find that coworking operators package and sell the physical, spatial and symbolic aspects of work to help certain workers signal their professional selves.
ODSS vs. ABSIS and PDAI oral parts in pemphigus vulgaris: inter‐rater reliability and testing times
Authors: Shamabadi Ahmad , Yazdinezhad Soodeh , Sadeghi Yasaman , Moradi Amir Reza , Yazdchi Arsalan , Teymourpour Amir , Faramarzi Atefeh , Seirafi Ramtin , Balighi Kamran , Mahmoudi Hamidreza , Daneshpazhooh Maryam 
Published: July 2022

AbstractObjectivesThe existence of standard methods for diagnosis and measuring the severity of diseases leads to a more accurate severity assessment, the possibility of following up, and the possibility of comparing the results of studies. This study aimed to compare different pemphigus vulgaris (PV) assessment methods regarding inter‐observer reliability and testing times—focusing on oral parts.Materials and MethodsTwo dermatologists evaluated orally involved PV patients by oral parts of Autoimmune Bullous Skin Disorder Intensity Score (ABSIS), Pemphigus Disease Area Index (PDAI), and Oral Disease Severity Score (ODSS).ResultsSeventy patients completed the study. The intraclass correlation coefficient showed the evaluators' agreements on ABSIS, PDAI, and ODSS with 0.98, 0.94, and 0.95, respectively. Reliability analyses showed near‐perfect relationships between each scoring methods pairs. There was no association between lesion sites and disease severity. The PDAI scoring duration was significantly shorter, and the ABSIS scoring duration was significantly longer.ConclusionODSS is valid for evaluating oral involvement in patients with PV and relates to ABSIS and PDAI almost perfectly. Besides, it was shown that the evaluation of patients' oral involvement based on PDAI and ODSS is done in about 1 min, which seems clinically reasonable.
Caring for people living with dementia in their own homes: A qualitative study exploring the role and experiences of registered nurses within a district nursing service in the UK
Authors: Hoe Juanita , Trickey Alison , McGraw Caroline 
Published: July 2022

AbstractBackgroundIn the UK, district nursing services (DNS) deliver care to people intheir own homes and have regular contact with people with dementia. Research conducted with nurses working in similar roles outside the UK suggests their contribution to high quality dementia care is limited by compassion fatigue, lack of dementia training and low levels of confidence. However, there is a paucity of research exploring the role and learning and support needs of nurses within DNS.ObjectivesThe aim was to gain insight into the role and experiences of nurses caring for people living with dementia at home.MethodsThe study was informed by a descriptive phenomenological approach. Semi‐structured interviews were conducted with a purposive sample of ten nurses working in DNS. Data were analysed thematically.ResultsFive main themes were identified: ‘Home as a care setting’ reflected how delivering home‐based care shaped participants experiences of caring for people with dementia; ‘Taking it in their stride’ revealed how participants adapted and responded to the complexity of care needs for people with dementia; ‘Complexity and unpredictability’ related to the unpredictable nature of people with dementia's care needs and the impact this had on participants' workloads; ‘Expertise and support within the wider team’ detailed which networks nurses used for advice and support to manage the complex needs of people living with dementia at home; ‘Specialist support’ identified the need for structural changes and resources to enable the nurses to deliver the care needed.ConclusionsThis study enables better understanding of the role of DNS in supporting people with dementia to live at home. This is important for defining how dementia care can become effectively integrated into primary care. Recommendations include improved models of care, which factor in specialist nurses, additional time for home visits and greater emphasis on education and training.Implications for practiceImproved models of working that factor in additional time and staffing such as specialist nurses in dementia and palliative care would allow DNS to meet the needs of people with dementia more effectively.