bluuebunny/crossref_metadata_2025_split huggingface dataset:
Self Care, Personality Traits, and Burnout in Emergency Nurses
Authors: Imardiani Imardiani , Efroliza Efroliza , Rusnida Ella 
Published: April 2022

Emergency nurses are health professionals who are very susceptible to burnout. There are many factors that influence nurses' burnout levels, including self-care and personality traits, but the relationship between burnout is still unclear. The purpose of the study was to determine the relationship between self-care and personality traits on nurse burnout in the emergency room at Palembang Hospital. This study used a design cross-sectional, a sample of 34 nurses was selected by probability sampling technique with the total sampling method. The instruments used in this research are Burnout Maslach Inventory (MBI), Mini-International Personality Item Pool (M-IPIP), and DSCPI-90. Data analysis used Pearson's test for self-care and burnout variables (r=-0.343; p<0.05), while variables personality traits and burnout used analysis with Spearman rho test for value Extraversion (r = -0.286 ; p> 0, 05), Agreeableness (r = -0.357 ; p < 0.05), Conscientiousness (r = 0.201; p> 0.05), Neuroticism (r = 0.436; p < 0.05), and Imagination (r = 0.328; p> 0.05). The conclusion is the importance of maintaining self-care as a factor that can reduce burnout, and the personality traits of nurses need to be known early so that appropriate action can be taken so that nurses can be protected from burnout.
UTILIZATION OF BLONDOS STONE ON POROUS CONCRETE
Authors: Ginting Arusmalem , Suyono  
Published: April 2022

Porous concrete can be used as a drainage system that allows rainfall to percolate into the ground, reduce stormwater runoff, and recharge groundwater. Porous concrete consists of coarse aggregate and cement paste. Stone mining waste in the river, namely medium-sized gravel which is often called blondos stone, has not been used optimally as a building material. Based on these reasons, it is tried to use blondos stone as coarse aggregate in porous concrete. Three variations of the gravel-cement ratio were used, that is: 4, 5, and 6, and 3 variations of the water-cement ratio, that is: 0.30, 0.35, and 0.40. There are 27 specimens of porous concrete cylinders, and each variation consists of 3 specimens. Permeability and compressive strength testing after 28 days of curing. The conclusions of this study are: increasing the water-cement ratio and gravel-cement weight ratio decreases the compressive strength and increases the permeability of the porous concrete. The water-cement ratio and gravel-cement weight ratio have no significant effect on the density of porous concrete. Blondos stone is adequate to be used for the manufacture of porous concrete.
Results of post-infarction left ventricular aneurysms surgical planning using magnetic resonance imaging and three-dimensional modeling
Authors: Kushnarev S. V. , Zheleznyak I. S. , Kravchuk V. N. , Rud S. D. , Shirshin A. V. , Menkov I. A. 
Published: April 2022

Aim. To evaluate the results of surgical intervention planning using three-dimensional models based on magnetic resonance imaging in patients with postinfarction left ventricular aneurysms.Material and Methods. Two groups of patients with postinfarction left ventricular aneurysm (PLVA) were included in the study, totaling 41 patients. The first (experimental) group included 17 patients diagnosed with PLVA by magnetic resonance imaging (MRI), and surgical intervention planning was performed using a 3D model of the heart. The control group comprised 24 patients in whom PLVA was diagnosed by echocardiography (TTE) or ventriculography, and surgical intervention planning was performed using traditional two-dimensional slice images.Results. Comparison of full perfusion under cardiopulmonary bypass (CPB) showed statistically significant differences between the groups: this parameter was 60 [56; 68] min in group 1 vs. 71 [61; 84] min in group 2, which was significantly higher (p = 0.043). There were no significant differences in total operation time (280 [265; 320] min in group 1 vs. 263 [248; 283] min in group 2, p = 0.055), overall CPB time (93 [86; 109] min in group 1 vs. 104 [83; 109] min in group 2, p = 0.653), and partial CPB time (31 [26; 39] min in group 1 vs. 27 [21; 32] min in group 2, p = 0.127).Conclusion. The use of 3D models to support surgeons for PLVA correction makes it possible to determine the type of reconstructive surgery, practice the main stages of the upcoming intervention, and reduce the time of full perfusion under CPB during its implementation.
Comparative retrospective analysis of the results of open femoral-popliteal bypass grafting and endovascular stenting with an interwoven biomimetic stent in patients with prolonged occlusions of the arteries in the femoropopliteal segment
Authors: Gostev A. A. , Osipova O. S. , Bugurov S. V. , Saaya Sh. B. , Rabtsun A. A. , Cheban A. V. , Ignatenko P. V. , Karpenko A. A. 
Published: April 2022

Introduction. Autovenous graft is considered the gold standard for prolonged occlusive lesions of the arteries in the femoralpopliteal segment. However, the vein is not always anatomically suitable for bypass grafting; it may have been previously used in previous operations, for example, in coronary artery bypass grafting. Open surgery is always more traumatic than endovascular surgery. Conventional nitinol stents show unsatisfactory results in the femoral-popliteal position due to the high percentage of reocclusions associated with their breakage during physiological movements in the leg joints. The modified method of making interwoven nitinol stents allows improving their biomimetic properties and reducing the percentage of breakages and, accordingly, reocclusions.Material and Methods. There was a retrospective analysis of 437 patients with prolonged atherosclerotic occlusive lesion in the femoropopliteal segment (> 20 cm). There were two groups: a group of bypass surgery and a group of endovascular intervention. The pseudo-randomization method of propensity score matching was used to align the groups according to various criteria.Results. Primary and secondary patency rates for one- and two-year follow up were comparable between the two groups. A subgroup analysis of above-knee intervention showed that a two-year secondary patency rate was significantly higher in the endovascular intervention group than in the bypass group (90.9% vs. 77.5%, p = 0.048). The subgroup analysis of interventions below the knee joint showed that the patency rates at two years of primary and primary-assisted patency were significantly higher in the endovascular intervention group than in the bypass group with an artificial expanded polytetrafluoroethylene (ePTFE) graft (66.7% versus 42.4%, p = 0.046 and 76.7% versus 45.5%, p = 0.011, respectively). The autovenous graft showed better results for primary patency compared with the endovascular intervention group, but the difference was statistically insignificant (77.2% versus 66.7%, respectively, p = 0.3).Conclusion. The analysis of obtained results suggests that the primary endovascular strategy may be recommended for all prolonged occlusive lesions of the femoropopliteal segment above the knee joint gap. For lesions below the knee joint, the autovenous bypass grafting remains the operation of choice, but in the absence of a suitable autovenous graft, the primary endovascular strategy may also be recommended. Additional large multicenter randomized trials are required to refine these recommendations.
Predictors of early adverse events after ascending aortic replacement
Authors: Kozlov B. N. , Panfilov D. S. , Sonduev E. L. , Lukinov V. L. 
Published: April 2022

Objective. The aim of this study was to identify predictors of adverse events after ascending aortic replacement for the aortic aneurysms in the early postoperative period.Material and Methods. The analysis included 151 patients with ascending aortic aneurysm who underwent non-hemiarch or hemiarch repair. The following adverse outcomes were selected: postoperative delirium, respiratory failure, bleeding, multiple organ dysfunction syndrome, and in-hospital mortality. Predictors of adverse clinical events were identified by constructing uni- and multivariate logistic regression.Results. Significant predictors of early outcomes and mortality after ascending aortic replacement were as follows: female gender, atrial fibrillation, low glomerular filtration rate, chronic obstructive pulmonary disease, aortic root repair, multiple organ dysfunction, duration of cardiac arrest, operation time, and reoperation for bleeding.Conclusions. The risk factors of adverse outcomes after ascending aortic replacement were decreased kidney function, atrial fibrillation, female gender, aortic root repair, and increased duration of cardiac arrest and operation time.
MRI diagnostics of a new type of stress subchondral insufficiency fracture of the knee
Authors: Ivankov A. P. , Seliverstov P. V. 
Published: April 2022

Subchondral insufficiency fracture of the knee is a new type of stress fracture, which was previously referred to as spontaneous osteonecrosis of the knee (SONK).Aim. To determine the informativeness of radiography and magnetic resonance imaging in subchondral fracture of knee insufficiency.Material and Methods. The study comprised 150 patients including 48% of men and 52% of women. The age of patients ranged from 46 to 82 years. The patients underwent radiography and magnetic resonance imaging of the knee joint followed by the calculation of sensitivity, specificity and accuracy of the methods.Results. The most common stress fracture of insufficiency was found in the medial condyle of the femur (79%) with the second most common in the lateral condyle of the femur (12%). Most fracture zones (7.9%) were localized in the medial condyle of the tibia, and only 1.1% of fracture zones were in the lateral condyle of the tibia. The informativeness of radiography was low: sensitivity of 68.4%, specificity of 30.0%, and accuracy of 55.1%. Parameters of magnetic resonance imaging informativeness were as follows: sensitivity of 100%, specificity of 99.0%, and accuracy of 98.0%.Conclusion. Magnetic resonance imaging is the method of choice for stress fracture knee insufficiency because it demonstrated very high indicators of informativeness.
Comparative characteristics of the quality of life in patients with senile asthenia and history of COVID-19 three and six months after discharge from the hospital
Authors: Petrov M. V. , Belugina T. N. , Burmistrova L. F. , Gracheva J. N. 
Published: April 2022

Background. Patients with COVID-19 and senile asthenia syndrome (SA) are characterized by extremely high comorbidity, heterogeneity, atypical course of the disease, and large number of complications. We carried out a comprehensive assessment of the quality of life (QOL) in patients with COVID-19 and SA considering the high prevalence of this category of patients and the absence of such studies.Material and Methods. Group 1 included 37 patients with SA and history of COVID-19 three months after discharge from the hospital. Group 2 included 35 patients with CA and history of COVID-19 six months later. Control group comprised 34 patients with SA aged over 65 years who did not have COVID-19. The assessment of QOL was carried out according to the SF-36 questionnaire.Results. There was a decrease in absolutely all indicators of physical and psychosocial aspects of health three months after discharge from the hospital. There was a more pronounced decrease in the scales of physical functioning (PF), role-physical functioning (RP), general health (GH), and mental health (MH) after six months. There was a lower QOL in female population according to most scales (PF, RP, GH, MH, and role-emotional functioning (RE)) regardless of the time from the moment of discharge from the hospital, and a higher incidence of depression compared to men.Conclusions. All QOL indicators of patients with SA and history of COVID-19 decreased within the first three months after discharge from the hospital. At the same time, after six months, a decrease in physical status was most pronounced, while the indicators of mental sphere reduced only according to the MH scale. At three and six months after discharge, the quality of life in the male population was higher than in the female population according to the same evaluation scales (PF, RP, GH, MH, and RE). The best indicators of pain scale in men were characteristic only for the first group of patients, whereas there was no statistically significant difference according to the social functioning and MH data. There was a higher incidence of depression in the female population, while the prevalence of anxiety was higher at three months after discharge than after six months.
Integration of multimedia components into the models of treatment and diagnostic process in patients and clinical diagnostic tasks in cardiology
Authors: Karas S. I. , Zavadovsky K. V. , Shelkovnikova T. A. , Gulyaev V. M. , Baev A. E. , Vaizov V. Kh. , Grakova E. V. , Balakhonova M. V. , Kara-Sal E. E. 
Published: April 2022

Introduction. Integration of multimedia results of diagnostic examinations into the information model of diagnostic and treatment process makes it possible to teach medical decision-making taking into account all available information about the patient.Aim. The purpose of this work was to use multimedia results of instrumental examination methods to form and verify the level of effective diagnostic decision-making.Material and Methods. A significant array of multimedia information arising in the course of treatment and diagnostic process was derived from databases of diagnostic units and was important for medical decision-making. The model was supplemented with clinically and demographically relevant studies of other patients when necessary. The multimedia components were integrated into the virtual simulations with two different trajectories of information presentation to the trainees depending on the purpose of further use.Results. At the first stage of the project, the multimedia components were integrated into linear models of completed cases to demonstrate medical decisions to the trainees. The multimedia components were presented as the fragments of magnetic resonance imaging (MRI) data, echocardiography and vascular ultrasound recordings, scanned electrocardiograms (ECG), angiography results, X-ray images, tomograms, and results of other visualization methods of patient examination. Each multimedia file was accompanied by a textual conclusion made by a relevant specialist. At the second stage, the multimedia components were integrated into the models with a branched trajectory of information presentation. The course of disease and the patient’s condition could change depending on the decisions made, which means that there are alternative scenarios of the therapeutic and diagnostic process unlike the real invariant treatment of the patient. This possibility is especially important for the formation of medical decision-making competencies in safe conditions of simulation. To elaborate clinical diagnostic tasks, the authors developed a rating system quantifying the effectiveness of the decisions.Discussion. Building physician competencies in the educational process through repeated decision-making under changing conditions is crucially important for the health and lives of patients and can be effectively implemented using simulation technologies. Web access to this content is strategically important for the use of virtual patients with multimedia diagnostic results to practice decision-making skills in clinical disciplines.
The effect of campaign of the plastic bag use reduction policy toward “green behavior” of Bogor City society
Authors: Carolin Lulik Tafsia  , Mulatsih Sri , Sumardjo  
Published: April 2022

The Municipal Government of Bogor City issued a regulation in reducing the use of plastic bags to decrease the volume of plastic waste in Bogor City. The regulation has been implemented since December 1st, 2018. This study aims to find out the influence of socialization policy on the awareness, attitudes, and actions of Bogor City Society in reducing the use of plastic bags. This study uses the analysis method of Structural Equation Modeling (SEM). The result of this study demonstrates that there is a positive relationship between policy socialization towards the forming of awareness, attitudes, and actions of Bogor City society in reducing the use of plastic bags, in addition, awareness and eco-friendly attitudes also have a positive influence on the forming of actions to reduce the use of plastic bags. Therefore, for the policy to run effectively, it is necessary to increase policy socialization to increasingly heighten awareness, attitudes, and actions of the Bogor City society in reducing the use of plastic bags.
Determination of Heavy Metals, Arsenic, and Aluminum Content in Pumpkin Seed Herbal Substance and Native Products, by Inductively Coupled Plasma Mass Spectrometry
Authors: Ovsienko S. V. , Shchukin V. M. , Blinkova E. A. , Kuz’mina N. E. 
Published: April 2022

Pumpkin seeds belong to the so-called native products. Their characteristic feature is that they can be consumed directly, without prior extraction of the starting material. All elemental toxicants contained in pumpkin seeds are transferred in full to the native product. Therefore, it is important to study specific aspects of elemental toxicant accumulation by pumpkin seeds.The aim of the study was to determine the content of heavy metals, As, and Al in pumpkin seed herbal substance and native products, and to assess the degree of accumulation of these elements, depending on the vegetation area.Materials and methods: the study evaluated pumpkin seed native products by Russian manufacturers as well as pumpkin seeds harvested in areas with different anthropogenic load. The sample preparation was performed by microwave digestion, and the determination of the elemental toxicants was perfomed by inductively coupled plasma mass spectrometry.Results: the pumpkin seeds were shown to contain essential, probably essential, potentially toxic, and toxic elements. The authors performed comparative analysis of the elemental composition of pumpkin seeds as well as seeds, grains, and beans of various oil-bearing, grain, and leguminous crops.Conclusions: the content of the specified elemental toxicants (As, Cd, Hg, Pb) in the tested samples of pumpkin seed herbal substance and herbal medicinal products did not exceed the limits established by the Russian Pharmacopoeia. The unspecified toxic elements were either absent in pumpkin seeds (Tl) or found in trace amounts (Al). The content of a number of essential elements (Zn, Fe, Mn, Cu, Mo, Cr) in pumpkin seeds was higher than in the seeds of many oil-bearing crops. The vegetation area had no significant influence on the content of the tested elements in the pumpkin seeds. Pumpkin seeds are capable of accumulating abnormally high amounts of Cd, Co, and Ni in areas with high environmental pollution.
The Use of Spectroscopic Methods for Structural Elucidation of Individual Secondary Metabolites Isolated from the Aerial Parts of Corydalis bracteata
Authors: Toporkova V. I. , Ponkratova A. O. , Whaley A. K. , Luzhanin V. G. , Goncharov M. U. 
Published: April 2022

Plants of the Corydalis (Papaveraceae) genus are widely used in oriental medicine and are known for their particularly rich content of biologically active substances. One of the species encountered in Russia, the large-flowered corydalis (Corydalis bracteata (Steph. ex Willd.) Pers.), is widespread in Western and Eastern Siberia, but none the less its chemical composition has not been properly studied yet.The aim of the study was to perform phytochemical analysis of Corydalis bracteata herb through isolation of the main secondary metabolites and elucidation of their structure, using modern chromatographic methods of analysis and NMR spectroscopy.Materials and methods: the analysis was performed for dried aerial parts of C. bracteata. The isolation of individual compounds was performed using open-column chromatography and glass columns packed with sorbents with different selectivity characteristics— Dianion® HP-20 (Supelco) and Sephadex® LH-20 (GE Healthcare)—as well as preparative-scale chromatography with a Kromasil® C18 column and detection at 235 nm. Water and acetonitrile mixed in the ratios 5:95–50:50 v/v with the addition of 0.1% trifluoroacetic acid were used as the eluents. The analysis of fractions before pooling was performed by high-performance thin-layer chromatography with Silica gel 60 F254 plates (Merck). The analysis of the individual compound solutions was performed by HPLC using a Prominence LC-20 (Shimadzu) instrument, a SUPELCOSIL™ LC-18 column, and detection at 235 nm. The structures of the isolated individual compounds were elucidated by one- and two-dimensional NMR spectroscopy using a Bruker Avance III 400 MHz NMR spectrometer.Results: four individual compounds from the С. bracteata aerial parts were isolated and analysed: an isoquinoline alkaloid— coptisine (1) and three flavonoids—rutin (2), quercetin-3-O-β-D-glucopyranoside (3), and kaempferol-3-O-β-D-glucopyranoside (4).Conclusions: as a result of the phytochemical analysis of the С. bracteata aerial parts, compounds of both alkaloid and flavonoid nature were isolated for the first time, and their structures were elucidated using NMR spectroscopy. С. bracteata should be considered as a promising potential source of biologically active substances.
Development and Validation of Procedures for Determination of Elemental Toxicants in Herbal Substances and Herbal Medicinal Products
Authors: Shchukin V. M. , Kuz’mina N. E. , Shvetsova Yu. N. , Luttseva A. I. 
Published: April 2022

When the approach to quality control of herbal substances (HSs) and herbal medicinal products (HMPs) changed from determination of the total content of heavy metals by calorimetry to selective determination by spectrometric techniques, many manufacturers of such products failed to meet the new requirements in their registration dossiers. Test procedures submitted by manufacturers often need to be clarified, and validation protocols often lack data.The aim of the study was to provide recommendations to HS and HMP manufacturers on the choice of test methods, materials, reagents, methods of organic matrix mineralisation, and main validation parameters, as well as recommendations on validation of the procedure for elemental toxicants determination, and preparation of the “Heavy metals and arsenic” part of the regulatory submission.Materials and methods: the study included analysis and systematisation of scientific literature, requirements of the Russian and foreign pharmacopoeias, guidelines, manuals on instrumental methods of analysis, and first-hand experience in elemental analysis of various types of HSs and HMPs.Results: the authors formulated recommendations on the choice of sample mineralisation conditions for quantification of elemental impurities in biological products, and substantiated requirements for the reagents, materials, and equipment. The paper compares different methods of elemental analysis. It was demonstrated that the main mistakes made by manufacturers stem from disregard to the organic matrix effect on the measurement results and lack of agreement between the impurity concentration being determined and the range of the calibration curve used. The paper gives acceptance criteria for validation parameters of test procedures for heavy metals and arsenic determination in HSs and HMPs.Conclusions: it is not correct to use reference standards containing heavy metals as inorganic salts not bound to organic compounds, for HS and HMP analysis. The criteria given in the European Pharmacopoeia and the United State Pharmacopoeia can be used for a number of validation parameters, when they are not included in the Russian Pharmacopoeia.