bluuebunny/crossref_metadata_2025_split huggingface dataset:
Forest Biomass Availability
Authors: Anttila Perttu , Verkerk Hans 
Published: August 2022

AbstractThe forest-based bioeconomy relies on using forests as a source of raw material for producing materials and energy, as well as for a variety of other ecosystem services. The uses of forests and wood are many and, to some extent, competing. Can a limited resource simultaneously and sustainably provide raw materials for products, feedstock for energy production, and other ecosystem services? Over one-third of the land area in the EU is covered by forests, but there are large differences between the member states regarding both forest area and growing stock of wood. The harvesting of roundwood has been steadily increasing. In addition to roundwood, other tree parts, as well as residues from forest industries and post-consumer wood, are being used for both materials and energy production. There are non-negligible uncertainties regarding the future availability of forest biomass in the context of climate change, as well as difficulties to concern all the relevant constraints on biomass supply in relation to availability assessments and the difficult-to-predict effects of policies. Despite the above, it can be concluded that there is still potential to increase the utilisation of forest biomass in most of the EU regions, but this might affect the provisioning of other important ecosystem services.
Dynamic Consent als Umsetzungsmechanismus von Datensouveränität
Authors: Hummel Patrik , Braun Matthias , Augsberg Steffen , Ulmenstein Ulrich von , Dabrock Peter 
Published: August 2022

ZusammenfassungDie Einwilligung stellt im deutschen wie im europäischen Recht die wichtigste Voraussetzung (Erlaubnistatbestand) für den Umgang mit personenbezogenen Daten dar. Mit Blick auf die Datenqualität und Repräsentativität kann ein striktes Einwilligungserfordernis ein Hemmnis für datenintensive Forschung darstellen. Ein Versuch mit diesem Dilemma umzugehen besteht darin, datenschutzrechtliche Standards bereichsbezogen aufzuspalten: Während (Gesundheits-)Versorgung auf einem Informed oder Narrow Consent basiert, wäre in der Forschung ein Broad Consent oder gar eine von der Einwilligung gelöste Verwendung zulässig. Wer grundrechtlich vorzugswürdig weiterhin primär auf ein einwilligungsbasiertes Regelungskonzept setzt (Opt-in-Modell), muss nach Mechanismen fragen, um Einwilligungsentscheidungen so treffen zu können, dass fortlaufende Kontrolle ermöglicht wird. Das verdeutlicht, warum es attraktiv ist, das Modell eines Dynamic Consent zu entfalten und kontextsensibel weiterzuentwickeln. Für eine robuste Umsetzung des Dynamic Consent bedarf es zugleich Delegationsmöglichkeiten. Der Einsatz sog. Datentreuhänder gehört zu den prominenten Vorschlägen, wie unter Big-Data-Bedingungen ein adäquater Datenschutz gewährleistet werden kann.
Governance-Ansätze
Authors: Hummel Patrik , Braun Matthias , Augsberg Steffen , Ulmenstein Ulrich von , Dabrock Peter 
Published: August 2022

ZusammenfassungWir haben argumentiert, dass Datensouveränität die Befähigung von Akteuren zu informationeller Freiheitsgestaltung durch Kontrolle der Verwendung sie betreffender Daten bezeichnet (Kap. 1). Im Anschluss haben wir den Dynamic Consent als Umsetzungsmechanismus von Datensouveränität vorgeschlagen (Kap. 2). Im Folgenden fokussieren wir vier miteinander in Wechselwirkung stehende Governance-Ebenen (siehe Abb. 3.1), auf denen Datensouveränität im deutschen Gesundheitssystem ermöglicht und gestärkt werden kann: Hard Law (3.1), Soft Law (3.2), Teilhabe (3.3) und IT (3.4).
Flipped Learning
Authors: Lee Jihyun 
Published: August 2022

AbstractFlipped learning (FL) began as a local trial strategy in a US high school in 2012 and in less than 10 years has exploded in popularity, among both educational practitioners and researchers, and has now been extensively recognized and implemented at all levels of education across the world. This chapter will discuss what is known from current FL literature, what the practical implications are from this literature, what gaps exist within FL research and between FL research and practices, and how those gaps should be addressed. This chapter begins with the definition and continues discussing history and supporting theories of flipped learning and its effectiveness, affecting factors, challenges, and possible solutions from current literature. In addition, as a modified version of traditional flipped learning, a fully online flipped learning model, bichronous online learning, and HyFlex learning are introduced. This chapter concludes with future research directions.
Comparison of dry and liquid carbon dioxide cutting conditions based on machining performance and life cycle assessment for end milling GFRP
Authors: Khanna Navneet , Rodríguez Adrián , Shah Prassan , Pereira Octavio , Rubio-Mateos Antonio , de Lacalle Luis Norberto López , Ostra Txomin 
Published: August 2022

AbstractIn the present scenario, citizens’ concern about environment preservation creates a necessity to mature more ecological and energy-efficient manufacturing processes and materials. The usage of glass fiber reinforced polymer (GFRP) is one of the emerging materials to replace the traditional metallic alloys in the automotive and aircraft industries. However, it has been comprehended to arise a sustainable substitute to conventional emulsion-based coolants in machining processes for dropping the destructive effects on the ecosystem without degrading the machining performance. So, in this study, the comparison of the two sustainable cutting fluid approaches, i.e., dry and LCO2, has been presented based on machining performance indicators like temperature, modulus of cutting force, tool wear, surface roughness, power consumption, and life cycle assessment (LCA) analysis for end milling of GFRP. The cutting condition of LCO2 has been found to be superior in terms of machining performance by providing 80% of lower cutting zone temperature, tool wear, 5% lower modulus of cutting force, and reduced surface roughness with 9% lower power consumption that has been observed in the case of LCO2 in comparison with dry machining. However, to compress the CO2 for converting in liquid form, a higher amount of energy and natural resources is consumed resulting in a higher impact on the environment in comparison with dry machining. Considering the 18 impact categories of ReCiPe midpoint (H) 2016, 95% higher values of impacts have been observed in the case of LCO2 in comparison with dry machining.
Imaging of heart disease in women: review and case presentation
Authors: Mikail Nidaa , Rossi Alexia , Bengs Susan , Haider Achi , Stähli Barbara E. , Portmann Angela , Imperiale Alessio , Treyer Valerie , Meisel Alexander , Pazhenkottil Aju P. , Messerli Michael , Regitz-Zagrosek Vera , Kaufmann Philipp A. , Buechel Ronny R. , Gebhard Cathérine 
Published: August 2022

AbstractCardiovascular diseases (CVD) remain the leading cause of mortality worldwide. Although major diagnostic and therapeutic advances have significantly improved the prognosis of patients with CVD in the past decades, these advances have less benefited women than age-matched men. Noninvasive cardiac imaging plays a key role in the diagnosis of CVD. Despite shared imaging features and strategies between both sexes, there are critical sex disparities that warrant careful consideration, related to the selection of the most suited imaging techniques, to technical limitations, and to specific diseases that are overrepresented in the female population. Taking these sex disparities into consideration holds promise to improve management and alleviate the burden of CVD in women. In this review, we summarize the specific features of cardiac imaging in four of the most common presentations of CVD in the female population including coronary artery disease, heart failure, pregnancy complications, and heart disease in oncology, thereby highlighting contemporary strengths and limitations. We further propose diagnostic algorithms tailored to women that might help in selecting the most appropriate imaging modality.
Pulmonary embolism response team (PERT) implementation and its clinical value across countries: a scoping review and meta-analysis
Authors: Hobohm Lukas , Farmakis Ioannis T. , Keller Karsten , Scibior Barbara , Mavromanoli Anna C. , Sagoschen Ingo , Münzel Thomas , Ahrens Ingo , Konstantinides Stavros 
Published: August 2022

Abstract
Background
Over the last years, multidisciplinary pulmonary embolism response teams (PERTs) have emerged to encounter the increasing variety and complexity in the management of acute pulmonary embolism (PE). We aimed to systematically investigate the composition and added clinical value of PERTs.

Methods
We searched PubMed, CENTRAL and Web of Science until January 2022 for articles designed to describe the structure and function of PERTs. We performed a random-effects meta-analysis of controlled studies (PERT vs. pre-PERT era) to investigate the impact of PERTs on clinical outcomes and advanced therapies use.

Results
We included 22 original studies and four surveys. Overall, 31.5% of patients with PE were evaluated by PERT referred mostly by emergency departments (59.4%). In 11 single-arm studies (1532 intermediate-risk and high-risk patients evaluated by PERT) mortality rate was 10%, bleeding rate 9% and length of stay 7.3 days [95% confidence interval (CI) 5.7–8.9]. In nine controlled studies there was no difference in mortality [risk ratio (RR) 0.89, 95% CI 0.67–1.19] by comparing pre-PERT with PERT era. When analysing patients with intermediate or high-risk class only, the effect estimate for mortality tended to be lower for patients treated in the PERT era compared to those treated in the pre-PERT era (RR 0.71, 95% CI 0.45–1.12). The use of advanced therapies was higher (RR 2.67, 95% CI 1.29–5.50) and the in-hospital stay shorter (mean difference − 1.6 days) in PERT era compared to pre-PERT era.

Conclusions
PERT implementation led to greater use of advanced therapies and shorter in-hospital stay. Our meta-analysis did not show a survival benefit in patients with PE since PERT implementation. Large prospective studies are needed to further explore the impact of PERTs on clinical outcomes.

Registration
Open Science Framework 10.17605/OSF.IO/SBFK9.

Graphical abstract
Clinical characteristics, causes and predictors of outcomes in patients with in-hospital cardiac arrest: results from the SURVIVE-ARREST study
Authors: Hannen Laura Erika Maria , Toprak Betül , Weimann Jessica , Mahmoodi Bahara , Fluschnik Nina , Schrage Benedikt , Roedl Kevin , Söffker Gerold , Kluge Stefan , Issleib Malte , Blankenberg Stefan , Kirchhof Paulus , Clemmensen Peter , Sinning Christoph , Zengin-Sahm Elvin , Becher Peter Moritz 
Published: August 2022

Abstract
Introduction
In-hospital cardiac arrest (IHCA) is acutely life-threatening and remains associated with high mortality and morbidity. Identifying predictors of mortality after IHCA would help to guide acute therapy.

Methods
We determined patient characteristics and independent predictors of 30-day in-hospital mortality, neurological outcome, and discharge/referral pathways in patients experiencing IHCA in a large tertiary care hospital between January 2014 and April 2017. Multivariable Cox regression model was fitted to assess predictors of outcomes.

Results
A total of 368 patients with IHCA were analysed (median age 73 years (interquartile range 65–78), 123 (33.4%) women). Most patients (45.9%) had an initial non-shockable rhythm and shockable rhythms were found in 20.9%; 23.6% of patients suffered from a recurrent episode of cardiac arrest. 172/368 patients died within 30 days (46.7%). Of 196/368 patients discharged alive after IHCA, the majority (72.9%, n = 143) had a good functional neurological outcome (modified Rankin Scale ≤ 3 points). In the multivariable analysis, return of spontaneous circulation without mechanical circulatory support (hazard ratio (HR) 0.36, 95% confidence interval (CI) 0.21–0.64), invasive coronary angiography and/or percutaneous intervention (HR 0.56, 95% CI 0.34–0.92), and antibiotic therapy (HR 0.87, 95% CI 0.83–0.92) were associated with a lower risk of 30-day in hospital mortality.

Conclusion
In the present study, IHCA was survived in ~ 50% in a tertiary care hospital, although only a minority of patients presented with shockable rhythms. The majority of IHCA survivors (~ 70%) had a good neurological outcome. Recovery of spontaneous circulation and presence of treatable acute causes of the arrest are associated with better survival.

Graphical abstract
Clinical Characteristics, Causes and Predictors of Outcomes in Patients with In-Hospital Cardiac Arrest: Results from the SURVIVE-ARREST Study. Abbreviations: CPR, cardiopulmonary resuscitation; IHCA, In-hospital cardiac arrest; MCS, mechanical circulatory support; PCI, percutaneous coronary intervention; ROSC, return of spontaneous circulation; SBP, systolic blood pressure.
A retrospective analysis of controlled active motion (CAM) versus modified Kleinert/Duran (modKD) rehabilitation protocol in flexor tendon repair (zones I and II) in a single center
Authors: Wirtz C. , Leclère F. M. , Oberfeld E. , Unglaub F. , Vögelin E. 
Published: August 2022

AbstractIntroductionThe aim of this study was to analyze primary flexor tendon repair results in zones I and II, comparing the rupture rate and clinical outcomes of the controlled active motion (CAM) protocol with the modified Kleinert/Duran (mKD) protocol.Materials and methodsPatients who underwent surgery with traumatic flexor tendon lacerations in zones I and II were divided in three groups according to the type of rehabilitation protocol and period of management: group 1 included patients who underwent CAM rehabilitation protocol with six-strand Lim and Tsai suture after May 2014. Group 2 and 3 included patients treated by six-strand Lim Tsai suture followed by a modified Kleinert/Duran (modK/D) protocol with additional place and hold exercises between 2003 and 2005 (group 2) and between 2011 and 2013 (group 3).ResultsRupture rate was 4.7% at 12 weeks in group 1 (3/63 flexor tendon repairs) compared to 2% (1/51 flexor tendon repairs) in group 2 and 8% in group 3 (7/86 flexor tendon repairs). The grip strength at 12 weeks was significantly better in group 2 compared to the group 1 (35 kg/25 kg,p = 0.006). The TAM in group 1 [113° (30–175°)] was significantly worse (p < 0.001) than the TAM in group 2 [141° (90–195°)] but with similar extension deficits in both groups. The assessment of range of motion by the original Strickland classification system resulted in 20% excellent and 15% good outcomes in the CAM group 1 compared with 42% and 36% in the modK/D group 2. Subanalysis demonstrated improvement of good/excellent results according to Strickland from 45% at 3 months to 63.6% after 6-month follow-up in the CAM group.ConclusionThe gut feeling that lead to change in our rehabilitation protocol could be explained by the heterogenous bias. A precise outcome analysis of group 1 could underline that in patients with complex hand trauma, nerve reconstruction, oedema or early extension deficit, an even more intensive and individual rehabilitation has to be performed to achieve better TAM at 6 or 12 weeks. Our study explicitly demonstrated a significant better outcome in the modK/D group compared to CAM group. This monocenter study is limited by its retrospective nature and the low number of patients.
Lattice Boltzmann method for antiplane shear deformation: non-lattice-conforming boundary conditions
Authors: Schlüter Alexander , Müller Henning , Müller Ralf 
Published: August 2022

AbstractIn this work, two different approaches to treat boundary conditions in a lattice Boltzmann method (LBM) for the wave equation are presented. We interpret the wave equation as the governing equation of the displacement field of a solid under simplified deformation assumptions, but the algorithms are not limited to this interpretation. A feature of both algorithms is that the boundary does not need to conform with the discretization, i.e., the regular lattice. This allows for a larger flexibility regarding the geometries that can be handled by the LBM. The first algorithm aims at determining the missing distribution functions at boundary lattice points in such a way that a desired macroscopic boundary condition is fulfilled. The second algorithm is only available for Neumann-type boundary conditions and considers a balance of momentum for control volumes on the mesoscopic scale, i.e., at the scale of the lattice spacing. Numerical examples demonstrate that the new algorithms indeed improve the accuracy of the LBM compared to previous results and that they are able to model boundary conditions for complex geometries that do not conform with the lattice.
Building trait datasets: effect of methodological choice on a study of invasion
Authors: Palma Estibaliz , Vesk Peter A. , Catford Jane A. 
Published: August 2022

AbstractTrait-based approaches are commonly used to understand ecological phenomena and processes. Trait data are typically gathered by measuring local specimens, retrieving published records, or a combination of the two. Implications of methodological choices in trait-based ecological studies—including source of data, imputation technique, and species selection criteria—are poorly understood. We ask: do different approaches for dataset-building lead to meaningful differences in trait datasets? If so, do these differences influence findings of a trait-based examination of plant invasiveness, measured as abundance and spread rate? We collected on-site (Victoria, Australia) and off-site (TRY database) height and specific leaf area records for as many species as possible out of 157 exotic herbaceous plants. For each trait, we built six datasets of species-level means using records collected on-site, off-site, on-site and off-site combined, and off-site supplemented via imputation based on phylogeny and/or trait correlations. For both traits, the six datasets were weakly correlated (ρ = 0.31–0.95 for height; ρ = 0.14–0.88 for SLA), reflecting differences in species’ trait values from the various estimations. Inconsistencies in species’ trait means across datasets did not translate into large differences in trait-invasion relationships. Although we did not find that methodological choices for building trait datasets greatly affected ecological inference about local invasion processes, we nevertheless recommend: (1) using on-site records to answer local-scale ecological questions whenever possible, and (2) transparency around methodological decisions related to selection of study species and estimation of missing trait values.
IgG4-related hypertrophic pachymeningitis with tumor-like intracranial and intracerebral lesions
Authors: Esmaeilzadeh Majid , Dadak Mete , Atallah Oday , Möhn Nora , Skripuletz Thomas , Hartmann Christian , Banan Rozbeh , Krauss Joachim K. 
Published: August 2022

Abstract
Objective
IgG4-related hypertrophic pachymeningitis is a rare fibroinflammatory disorder that may cause localized or diffused thickening of the dura mater. Misinterpretations of the clinical and imaging findings are common. Clinical manifestations depend on the location of the inflammatory lesion and on compression of neural structures leading to functional deficits. A dural biopsy is commonly needed for a definitive diagnosis. Immunomodulatory therapy is considered the therapy of choice.

Methods
Four patients with IgG4-related hypertrophic pachymeningitis were identified over a 5-year period. Patient-related characteristics including age, preoperative workup, signs and symptoms of patients, and diagnostic procedures were evaluated. Furthermore, the surgical treatment and 5-year follow-up outcomes were analyzed.

Results
There were two adults and two adolescents (mean age 32 years; range 15 to 67 years). Two patients were male, and two were female. No history of disease was known in any of the patients. Clinical symptoms were epilepsy (n = 2), ataxia and nausea (n = 1), and facial nerve palsy (n = 1). MR imaging studies showed contrast enhancing lesions in the temporal region in two patients, and in the cerebellar region in the other two patients. Subtotal resection was performed in two instances and a biopsy via a suboccipital retrosigmoid approach was obtained in the other two patients. Histochemical and immunohistochemical investigations revealed an IgG 4 disease in all of these patients. Immunomodulatorry therapy led to clinical stability during follow-up of 5 years in all four cases.

Conclusion
The diagnosis of IgG4-related hypertrophic pachymeningitis is challenging, but is of great relevance as treatment differs significantly from other forms of pachymeningitis and a specific therapeutic approach may avoid long-term neurological complications. Our series contributes to a better clinical characterization of this rare disease.
Clinical performance of different types of dental prosthesis in patients with head and neck tumors—a retrospective cohort study
Authors: Zierden Karina , Wöstmann Juliane , Wöstmann Bernd , Rehmann Peter 
Published: August 2022

Abstract
Objectives
To
investigate how different types of dental prosthesis perform in patients with head and neck tumors.

Materials and methods
In this retrospective clinical cohort study, the impact of different patient-related factors was analyzed as influencing factors on the survival probability of dental prosthesis using Kaplan–Meier estimate. For analysis, the dental prosthesis was divided into groups: group 1 (fixed dental prosthesis), group 2 (removable dental prosthesis), group 3 (implant-supported dental prosthesis), and group 4 (prostheses anchored using wrought wire clasps and obturators). The incidental aftercare measures were also evaluated.

Results
Two hundred seventy-nine restorations were observed (mean observation: 2.7 ± 3.0 years, max.14.8 years) out of which 49 (17.6%) had to be replaced during the observation. After 5 years, 100% of group 1 restorations, 79.9% of group 2 restorations, 91.4% of group 3 restorations, and 30% of group 4 restorations were still functional. Four hundred eighty-eight dental implants were observed, of which 77 (15.8%) failed.

Conclusions
Groups 1, 2, and 3 restorations showed good survival times after 5 years in function, whereas group 4 presented the worst survival times. Group 2 restorations showed the highest amount of necessary aftercare measures.

Clinical relevance
The current investigation shows that groups 1, 2, and 3 restorations should be preferred in the prosthetic treatment planning of patients with head and neck tumors. A treatment with group 4 restorations should only be considered if no other prosthetic treatment is possible or as temporary treatment.
Occurrence, transformation, bioaccumulation, risk and analysis of pharmaceutical and personal care products from wastewater: a review
Authors: Anand Uttpal , Adelodun Bashir , Cabreros Carlo , Kumar Pankaj , Suresh S. , Dey Abhijit , Ballesteros Florencio , Bontempi Elza 
Published: August 2022

AbstractAlmost all aspects of society from food security to disease control and prevention have benefited from pharmaceutical and personal care products, yet these products are a major source of contamination that ends up in wastewater and ecosystems. This issue has been sharply accentuated during the coronavirus disease pandemic 2019 (COVID-19) due to the higher use of disinfectants and other products. Here we review pharmaceutical and personal care products with focus on their occurrence in the environment, detection, risk, and removal.