bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of alpha-lipoic acid and Silybum marianum supplementation with a Mediterranean diet on metabolic dysfunction-associated steatosis
Authors: Cano Contreras Ana D , Del Rocío Francisco María , Vargas Basurto Jose L , Gonzalez-Gomez Kevin D , Amieva-Balmori Mercedes , Roesch Dietlen Federico , Remes-Troche José M 
Published: January 2025

BACKGROUND
The treatment of metabolic dysfunction-associated steatotic liver disease (MASLD) has focused on the control of comorbidities. Silybum marianum (SM) and alpha-lipoic acid (ALA) have shown antioxidant and adjuvant effects on the control of metabolic disorders.
AIM
To evaluate whether the SM-ALA formulation (LUDLEV®), in combination with the Mediterranean diet (MD), could improve MASLD-related liver injury.
METHODS
A randomized, double-blind clinical trial was conducted on patients with MASLD. Administration of SM-ALA plus MD (group A) vs placebo plus MD (group B) was compared for 24 weeks. At baseline and weeks 12 and 24, anthropometric measurements, metabolic parameters, and liver function were analyzed. Clinical effectiveness was evaluated through transient elastography.
RESULTS
Fifty patients aged 54 ± 10 years were included, and the majority (74%) were female. Reduced visceral fat and umbilical circumference were reported in both groups, with significance in group A (P = 0.045 and 0.003, respectively). The decrease in controlled attenuation parameter was gradual and maintained at 12 and 24 weeks in group A (P = 0.026), whereas in group B the decrease was greater at week 12 and remained unchanged at week 24 (∆controlled attenuation parameter: -27 dB/m). Mild adverse effects were reported in 4 patients in group A (16%) and 4 patients in group B (16%), with no significant differences between groups (P = 0.641).
CONCLUSION
SM-ALA (LUDLEV®) combined with the MD can promote the improvement of metabolic parameters, reducing visceral fat and hepatic steatosis in Mexican patients with MASLD.
Медична евакуація на полі бою: роль та відповідальність командирів за її організацію та проведення
Authors: Zhahovskiy V. O. , Livinskiy V. G. 
Published: January 2025

Мета роботи. Дослідження ролі та відповідальності командирів військових частин (з’єднань) і військових підрозділів за організацію та проведення медичної евакуації поранених, уражених і травмованих (поранені) військовослужбовців на полі бою, яка є важливою складовою лікувально-евакуаційних заходів в системі медичного забезпечення Збройних Сил (ЗС) України.
Матеріали та методи. Використано законодавчі та нормативно-правові акти з питань охорони здоров’я та оборони держави, доктринальні та керівні документи, публікації з питань військової охорони здоров’я та медичного забезпечення ЗС України, а також доктринальні документи НАТО з питань медичного забезпечення військ. Методи дослідження: бібліографічний, аналітичний, системного підходу, узагальнення.
Результати. Досліджено та висвітлено вимоги законодавства та нормативно-правових актів з питань військової охорони здоров’я, а також доктринальних і керівних документів з медичного забезпечення ЗС України в контексті організації та проведення медичної евакуації. Встановлено, що в умовах сучасної війни медична евакуація є найважливішим засобом забезпечення своєчасного надання всіх видів медичної допомоги пораненим військовослужбовцям. Вона передбачає швидку доставку військовослужбовців саме на ті етапи медичної евакуації, на яких найбільш раціонально та за медичними показаннями відповідно до бойової і медико-тактичної обстановки можна надати їм першу лікарську, кваліфіковану та спеціалізовану медичну допомогу, а також провести стаціонарне лікування і медичну реабілітацію до повного одужання. Стверджується, що законодавчими та нормативно-правовими актами, доктринальними і керівними документами з питань військової охорони здоров’я та медичного забезпечення ЗС України загальна відповідальність за збереження життя військовослужбовців та організацію медичного забезпечення військ (сил) покладається на командувачів (командирів) всіх рівнів військового управління.
Висновки. В умовах відбиття повномасштабної збройної агресії російської федерації проти України медична евакуація є найважливішим засобом забезпечення своєчасного надання всіх видів медичної допомоги пораненим військовослужбовцям. Враховуючи що медична евакуація є невід’ємною частиною медичного забезпечення військ (сил), а саме важливою складовою лікувально-евакуаційних заходів, загальна відповідальність за розшук, збір, винос (вивіз) поранених з поля бою та проведення передової медичної евакуації покладається на командирів військових підрозділів, військових частин (з’єднань).
Pendidikan Busana Muslimah Untuk Suku Baduy: Analisis Kebutuhan dan Tantangan
Authors: Ria Indriati  , Chaira H Saidah Yusrie  , Riyanto  
Published: January 2025

This research aims to be an input for the community, especially Muslim women in the Outer Baduy tribe community in the Dangka area, Banten Province, Indonesia, to be taken into consideration in choosing and wearing Muslimah clothing that is in accordance with Islamic law but can be adjusted and harmonised without leaving the characteristics of the customs and culture of the Baduy tribe, including by: (1) Assisting in providing solutions that are in accordance with the needs of Muslimah clothing for the Baduy community. (2) Providing useful information for the development of Muslimah fashion education that is adjusted to the customs and culture of the Baduy Tribe. (3) Provide a better understanding of the challenges faced in the development of Muslimah fashion education for Baduy Tribe. (4) Providing recommendations that can be used to overcome the challenges faced in the development of Muslimah fashion education for the Baduy Tribe. (5) Adding awareness in the community about the importance of Muslimah fashion education that can be adjusted to the customs and culture for the Baduy community. (6) To be a reference for further development of Muslimah fashion education in the context of Baduy Tribe and other similar contexts. (7) Providing benefits in aspects such as community development, community empowerment, expansion of Muslimah fashion education well.
Actualización en el tratamiento de Helicobacter pylori: revisión del LATAMGCHMSG
Authors: Otero R. William , Riquelme Arnoldo , Remes-Troche José María , Laudanno Oscar , Piscoya Alejandro , Marulanda Hernando , Otero Lina , Reyes-Placencia Diego 
Published: January 2025

El Helicobacter pylori (H. pylori) es el principal agente etiológico del adenocarcinoma gástrico, el cual afecta a más del 60% de la población mundial y con una prevalencia importante en América latina. Debido a sus consecuencias en la población afectada, es importante conocer las herramientas disponibles para establecer el diagnóstico de esta infección. Si bien, las terapias asociadas a claritromicina aún son ampliamente utilizadas, las importantes tasas de resistencia a este antibiótico en la región obligan a establecer como estándar de tratamiento otras terapias de mejor eficacia, como la cuadriterapia con bismuto o la terapia dual con amoxicilina en altas dosis. En el caso de pacientes con infección refractaria, los registros de datos locales son de utilidad para la toma de decisiones.
Emergent physics
Authors: Amador Eduardo Xavier 
Published: January 2025

In this essay we present a brief critical scrutiny of some popular theoretical models developed by the scientific community within the framework of Fundamental Physics. These models develop the hypothesis that it is possible that current physical laws can be derived or emerge from much more fundamental physical entities than those studied to date, which constitutes another way to achieve the Unification of said laws within a single common conceptual structure. We expose String-nets of Condensed Matter Physics, Loop Quantum Gravity, Superstrings and Branes, Entropic Gravity, the BCJ model, Stochastic Quantum Mechanics, Matrix Statistical Quantum Mechanics, and AdS/CFT Duality. These models are a small sample of an important trend that is gaining strong momentum within the scientific community.
Financial and economic performance of agricultural enterprises: analysis and policy improvement
Authors: Boiko Vitalii , Lyzak Mykhailo , Vasyltsiv Taras , Lupak Ruslan , Ohinok Solomiia 
Published: January 2025

Purpose. The article aims to develop theoretical and applied foundations for forming a methodology to evaluate financial and economic performance of agricultural enterprises.
Methodology / approach. The authors’ methodology for analysing enterprises’ financial and economic performance is formed in the research. This methodology is based on the use of the principal component analysis. Its use involves the composition of a series of empirical indicators of financial and economic performance based on a temporal approach, the calculation of coefficients of significance of indicators and components, and the calculation of combined and integral indicators of financial and economic performance. The developed methodology was tested using the example of 13 agricultural enterprises. The selected enterprises operate in the Lviv region of Ukraine. The study period covers the operational indicators of agricultural enterprises from 2017 to 2022. The Principal Component Analysis (PCA) method was employed to calculate the integral index of financial and economic performance for these agricultural enterprises. Econometric modeling was applied to identify the key determinants influencing the formation of this integral index.
Results. The research results showed that despite the availability of resource capacities of agricultural enterprises, the process of forming their financial and economic performance is subject to the destabilising influence of war and market factors. The integral index of agricultural enterprises’ financial and economic performance has significantly impacted their operational efficiency. Through the application of econometric modelling, the primary determinants influencing the formation of this integral index of financial and economic performance in agricultural enterprises have been identified. To improve the financial and economic performance of farming enterprises, a targeted mechanism is developed that is aggregated from such strategic areas as the rationalisation of production costs, the improvement of financial and economic management, better budgeting, the development of management personnel, and the restructuring of market policy.
Originality / scientific novelty. The originality of research lies in developing a methodology for assessing enterprises’ financial and economic performance using key indicators and components. This methodology creates an adequate information and analytical basis for improving the management of financial and monetary resources.
Practical value / implications. The practical significance of the research results consists in the possibility of their application in the economic activity of agricultural enterprises to improve the process of forming the financial and economic performance of the latter.
Effect of supplemental dietary phytogenic blends on growth performance, jejunal histomorphometry, and jejunal immunity of broiler chickens
Authors: Ceylan Ahmet , Saçaklı Pınar , Özgenç Çınar Özge , Ramay Muhammad Shazaib , Ahsan Umair , Harijaona Josoa André , Bayraktaroğlu Alev Gürol , Manghebati Fabrice , Calik Ali 
Published: January 2025

Abstract. This study evaluated the effects of two phytogenic blends on broiler performance, intestinal histomorphology, CD4+ (cluster of differentiation) and CD8+ T-cell numbers, and mRNA abundances of several cytokines in broilers. For this purpose, a total of 300 Ross 308 male broiler chicks that were 1 d old were randomly allocated to five experimental groups. The control group was fed a basal diet without any additives, and there were two phytogenic supplement groups (blend A, mainly comprising extracts of Thymus vulgaris and Filipendula ulmaria, and blend B, consisting of Ginkgo
biloba and Silybum marianum) with two dosage regimens each (100 and 200 mg kg−1 (denoted A100 and A200) and 100 and 300 mg kg−1 (B100 and B300) of the diet, respectively). Over the total growing period, body weight gain and feed intake were unchanged among the groups, although phytogenic blend B showed a dose-dependent improvement in feed conversion ratio. Both phytogenic blends did not affect carcass characteristics. Jejunal morphology (villus height, crypt depth, and their ratio) was modified depending on both the composition and the dosage levels of the selected phytogenics. Also, both phytogenic blends linearly increased the CD4+ and CD8+ T-cell numbers in the jejunum. Moreover, no major treatment effects were observed on mRNA abundances of cytokines (IL-1β, IL-6, and TNFα). However, across the two phytogenic additives employed, a positive linear dose response in IL-1β abundance was noted on day 21 in broilers fed phytogenic blend B. Overall, dietary phytogenic blend B improved the intestinal health and growth performance of chickens compared to blend A. Further studies are suggested to elucidate the effects of the tested phytogenic blends on gut microbiome and on oxidative stress in broiler chickens.
Investigating the role of gravity waves in mesosphere and lower-thermosphere (MLT) inversions at low latitudes
Authors: Lingerew Chalachew , Raju U. Jaya Prakash 
Published: January 2025

Abstract. The mesosphere and lower-thermosphere (MLT) transitional region, encompassing a height range of 60–100 km, is a distinct and highly turbulent zone within Earth's atmosphere. The region is significant owing to dynamics of atmospheric processes like planetary, tidal, and particularly gravity waves, which contribute to the formation of the mesospheric inversion layer (MIL). Investigating these inversion phenomena is crucial for understanding the dynamics of the middle and upper atmosphere, especially regarding stability and energy transfer. These phenomena are associated with energy transfer processes vital for understanding the overall dynamics of the atmosphere. Despite extensive studies on inversions, the formation mechanisms of mesospheric inversions remain poorly understood. Here, upper and lower inversion phenomena and their causative mechanisms are explored. The study utilizes long-term SABER (Sounding of the Atmosphere using Broadband Emission Radiometry) observations during 2005–2020 over the latitudinal, 3–15° N, and longitudinal, 33–48° E, ranges. The results show that the upper inversion occurs more frequently, with a frequency below 40 %, compared to the lower inversion, which occurs below 20 %. The upper inversion occurs within the height range of 78–91 km, with an inversion amplitude of approximately 20–80 K and a thickness of around 3–12 km. In contrast, the lower inversion is confined to the height range of 70–80 km, with an inversion amplitude of about 10–60 K and a thickness of around 4–10 km. Moreover, the gravity wave indicator potential energy shows high energy (below 100 J kg−1) in the upper-MLT region (85–90 km) compared to the lower-MLT region (70–75 km), with less than 50 J kg−1. Considering gravity waves, the Brunt–Väisälä frequency (N2) stability criteria indicate instability in the upper-MLT region, with very low values compared to the lower-MLT region. This suggests that the high amount of gravity wave potential energy is a consequence of the higher instability in the upper inversion compared to the lower inversion.
Lena River biogeochemistry captured by a 4.5-year high-frequency sampling program
Authors: Juhls Bennet , Morgenstern Anne , Hölemann Jens , Eulenburg Antje , Heim Birgit , Miesner Frederieke , Grotheer Hendrik , Mollenhauer Gesine , Meyer Hanno , Erkens Ephraim , Gehde Felica Yara , Antonova Sofia , Chalov Sergey , Tereshina Maria , Erina Oxana , Fingert Evgeniya , Abramova Ekaterina , Sanders Tina , Lebedeva Liudmila , Torgovkin Nikolai , Maksimov Georgii , Povazhnyi Vasily , Gonçalves-Araujo Rafael , Wünsch Urban , Chetverova Antonina , Opfergelt Sophie , Overduin Pier Paul 
Published: January 2025

Abstract. The Siberian Arctic is warming rapidly, causing permafrost to thaw and altering the biogeochemistry of aquatic environments, with cascading effects on the coastal and shelf ecosystems of the Arctic Ocean. The Lena River, one of the largest Arctic rivers, drains a catchment dominated by permafrost. Baseline discharge biogeochemistry data are necessary to understand present and future changes in land-to-ocean fluxes. Here, we present a high-frequency 4.5-year-long dataset from a sampling program of the Lena River's biogeochemistry, spanning April 2018 to August 2022. The dataset comprises 587 sampling events and measurements of various parameters, including water temperature, electrical conductivity, stable oxygen and hydrogen isotopes, dissolved organic carbon concentration and 14C, colored and fluorescent dissolved organic matter, dissolved inorganic and total nutrients, and dissolved elemental and ion concentrations. Sampling consistency and continuity and data quality were ensured through simple sampling protocols, real-time communication, and collaboration with local and international partners. The data are available as a collection of datasets separated by parameter groups and periods at https://doi.org/10.1594/PANGAEA.913197 (Juhls et al., 2020b). To our knowledge, this dataset provides an unprecedented temporal resolution of an Arctic river's biogeochemistry. This makes it a unique baseline on which future environmental changes, including changes in river hydrology, at temporal scales from precipitation event to seasonal to interannual can be detected.
Post-traumatic stress disorder, stress burden, and quality of life among caregivers of children with cancer in Egypt
Authors: Ramy Hisham A. , Sultan Sara M. , Salama Rasha A. 
Published: January 2025

Caregivers of children with cancer frequently endure considerable psychological distress. The challenging nature of caregiving, combined with the emotional burden of witnessing a child's illness and treatment, can impact the quality of life and lead to the development of post-traumatic stress disorder (PTSD) in these caregivers. The aim of this study was to assess the prevalence of PTSD among caregivers of pediatric cancer patients and to identify the risk factors contributing to its development. Additionally, it examined the stress burden on caregivers and its impact on their quality of life. A cross-sectional comparative study was conducted over six months at the outpatient pediatric oncology clinics in Ain Shams University Hospital and the National Cancer Institute, Cairo, Egypt. The Post-Traumatic Stress Disorder Checklist for DSM-5, Zarit Burden Interview, and PCASEE quality of life were utilized to assess the PTSD symptoms, perceived burden, and quality of life, respectively. A total of 60 caregivers of children with cancer and 60 caregivers of children without cancer were included. Among the caregivers of children with cancer, 91.3% (n=55) exhibited post-traumatic stress symptoms, with 31.3% (n=19) meeting the diagnostic criteria for PTSD, compared to 0% of caregivers of children without cancer. Caregivers of children with cancer had significantly higher stress burden and lower quality of life scores compared to caregivers of children without cancer (48.66±9.95 vs 13.25±5.64; p=0.001 and 51.8±15.2 vs 72.2±14.3; p<0.001, respectively). Young age (p=0.033), being a mother (p=0.003), and taking care of those with tumor relapse (p=0.012) were identified as significant factors associated with PTSD development among caregivers of cancer patients. Moreover, caregivers of children with cancer experienced significantly higher stress burden levels and reduced quality of life compared to those caring for children without cancer (p=0.001), further increasing their risk of developing PTSD. These findings highlight the critical need for targeted psychological support and interventions to improve the well-being of these caregivers.
El concepto económico de desarrollo: tesis interpretativa sobre la relación entre los "escritos de circunstancia" y la teoría económica de Marx
Authors: Lorenzo Ezequiel Matías , Moyano Martín 
Published: January 2025

La idea del desarrollo capitalista como una fuerza tendiente a homogeneizar la estructura económica a escala internacional puede rastrearse en ciertos pasajes de la obra económica de Karl Marx, incluyendo el prólogo a la primera edición alemana de El Capital. Sin embargo, esta tesis parece entrar en contradicción con otros escritos menos conocidos donde el autor esboza consideraciones sobre la relación entre sociedades con diferentes grados de desarrollo. El nexo entre estos distintos momentos de su obra ha suscitado un gran número de interpretaciones. En el presente artículo discutimos una que ha tenido gran impacto en estas latitudes, la de José Aricó en su libro Marx y América Latina. Proponemos una interpretación distinta que retoma los planteos de Pablo Levín y que, a nuestro juicio, nos permite realizar una serie de precisiones analíticas necesarias para volver coherentes cada uno de esos momentos de la obra de Marx en una teoría más avanzada del desarrollo capitalista. Hacia el final del trabajo extraemos algunas conclusiones de lo anteriormente planteado.
Pobreza multidimensional pospandemia en una ciudad intermedia: el caso de Bahía Blanca
Authors: Santos Maria Emma 
Published: January 2025

Este trabajo ofrece una suerte de ‘radiografía de la pobreza’ en una ciudad intermedia de gran relevancia para el sur argentino: Bahía Blanca. Se presentan estimaciones de un Índice de Pobreza Multidimensional a partir de una fuente de datos sin precedentes para la ciudad por su tamaño muestral y cobertura. Se encuentra que, a fines del año 2021, un 28% de la población, casi 82 000 personas, habitaba en hogares en pobreza multidimensional intensa a severa, de los cuales casi 30 000 eran niños, niñas y adolescentes, y un 15% de la población habitaba en hogares con inseguridad alimentaria moderada a severa. Se observa además un significativo grado de segregación socioespacial entre barrios vulnerables y no-vulnerables, especialmente cuando se considera la población de niños, niñas y adolescentes.
The Psych Behind Psychedelics: Exploring Hallucinogen Use as a Marker for Untreated Mental Health Disorders
Authors: Ahmed Liyana , Konda Sanjana , Ganti Latha 
Published: January 2025

Objective Are individuals who use hallucinogens self-medicating their mental illness and are they more likely to abuse other illegal substances? Design, setting, participants Data from the National Survey on Drug Use and Health (NSDUH), collected by the Substance Abuse and Mental Health Services Administration (SAMHSA) database was queried for correlations with hallucinogen use. Using age group as a control variable, different variables were run through a crosstab in order to find significant data pointing to the implications of hallucinogen use. Results The data from the crosstab analysis showed three key findings about hallucinogen use: Those with mental illness or substance abuse issues were substantially more likely to use hallucinogens, the hallucinogen use greatly increased with the pandemic along with further mental health issues, and those who used hallucinogens were more significantly likely to abuse other illegal substances, primarily in a younger population. Conclusion The positive correlation between mental health issues and hallucinogen use emphasizes the need for better mental health services, especially after the COVID-19 pandemic. The positive correlation between hallucinogen use and other drug use indicates the widespread drug abuse problem, especially within a younger population in which drugs pose a larger neurological threat.