bluuebunny/crossref_metadata_2025_split huggingface dataset:
CBCT in dental age estimation: A systematic review and meta analysis
Authors: Merdietio Boedi Rizky , Shepherd Simon , Mânica Scheila , Franco Ademir 
Published: January 2022

Objectives: This study aimed to investigate the reproducibility of dental age estimation methods in cone beam computed tomography (CBCT) and the correlation between dental (DA) and chronological (CA) ages. Methods: The scientific literature was searched in six databases (PubMed, Scopus, LILACS, Web of Science, SciELO, and OATD). Only observational studies were selected. Within each study, the outcomes of interest were (I) the quantified reproducibility of the method (κ statistics and Intraclass correlation coefficient); and (II) the correlation (r) between the dental and chronological ages. A random-effect three-level meta-analysis was conducted alongside moderator analysis based on methods, arch (maxillary/mandibular), population, and number of roots. Results: From 671 studies, 39 fulfilled the inclusion criteria, with one study reporting two different methods. The methods used in the studies were divided into metric (n = 17), volumetric (n = 20), staging (n = 2), and atlas (n = 1). All studies reported high examiner reproducibility. Group 1 (metric and volumetric) provided a high inverse weighted r ([Formula: see text] = −0.71, CI [-0.79,–0.61]), and Group 2 (staging) provided a medium-weighted r ([Formula: see text] = 0.49, CI [0.44, 0.53]). Moderator analysis on Group one did not show statistically significant differences between methods, tooth position, arch, and number of roots. An exception was detected in the analysis based on population (Southeast Asia, [Formula: see text] = −0.89, CI [-0.94,–0.81]). Conclusion: There is high evidence that CBCT methods are reproducible and reliable in dental age estimation. Quantitative metric and volumetric analysis demonstrated better performance in predicting chronological age than staging. Future studies exploring population-specific variability for age estimation with metric and volumetric CBCT analysis may prove beneficial.
Incidence of and Risk Factors for Perioperative Cardiovascular Complications in Spine Surgery
Authors: Chotisukarat Haruthai , Akavipat Phuping , Suchartwatnachai Pathomporn , Sookplung Pimwan , Eiamcharoenwit Jatuporn 
Published: January 2022

Background: An increasing number of patients are opting for spine surgery despite the associated risk of cardiovascular complications. The evidence regarding the incidence and risk factors of cardiovascular complications in spine surgery is insufficient. Therefore, we aimed to determine the incidence and risk factors for cardiovascular complications that occur perioperatively in spine surgery. Methods: This retrospective study included all patients who underwent spine surgery between January 2018 and December 2019 at a single center. Demographic, clinical, and operative data were collected from electronic medical records. The incidence of perioperative cardiac complications was determined. Univariate and multivariate analyses were performed to identify risk factors for the development of perioperative cardiovascular complications in the participants. Results: Of the 1,002 eligible patients enrolled in the study, six developed cardiac complications. Acute myocardial infarction, cardiac arrest, and congestive heart failure occurred in one, two, and three patients, respectively. Risk factors for cardiovascular complications included scoliosis surgery (relative risk: RR, 18.61; 95% confidence interval (CI): 1.346-257.35) and a history of congestive heart failure (RR, 120.97; 95% CI: 2.12-6898.80). Conclusion: The incidence of perioperative cardiovascular complications in patients who underwent spine surgery was 0.6%. High-risk patients should be closely monitored optimally managed throughout the perioperative period.
Does the use of mobile applications or mobile health technology improve diet quality in adults? A protocol for a systematic literature review
Authors: Scarry Alan , Rice Jennifer , O' Connor Eibhlís M , Tierney Audrey C 
Published: January 2022

Background: Mobile technology has grown at an exceptional rate and is now a huge part of our daily living. This use of mobile technology has opened up new possibilities in treating health, with almost half of the current applications linked to the mHealth sector. In particular, dietary measurement, applications have become very accessible and very popular. As dietary issues have become more prevalent, more mobile and mHealth applications offer various solutions. This systematic review aims to address if the use of such mobile applications or mobile health technology can improve diet quality in adults that interact with them. Methods: A systematic review of randomised controlled trials (RCTs) and non-randomised controlled trials (NRCTs) will be conducted. The Cumulative Index to Nursing and Allied Health Literature (Cinahl), The American Psychological Association’s (APA Psycinfo), and PubMed will be searched from January 2010 to November 2021. Primary outcomes will include identifying if adults who use mobile applications and health technology improve their diet quality compared to adults who do not use this technology. Study selection will follow the Preferred Reporting Items for Systematic Reviews and MetaAnalyses (PRISMA) guidelines. The methodological appraisal of the studies will be assessed independently by two different reviewers (AS and JR) using the Cochrane Risk-of-Bias Tool for RCTs and the Risk-of Bias In Non-Randomised Studies Tool for NRCTs. Ethics and dissemination: Ethical approval is not essential for this systematic review. Only data from studies that are publically available from previously published studies will be used. The findings of this systematic review will be submitted for publication in a peer-reviewed journal and presented at relevant conferences. PROSPERO registration: CRD42021240224 (01/03/2021).
Semantic competency as a marker of clinical reasoning performance
Authors: Berge Michael , Soh Michael , Fahlsing Christopher , MacKinnon Rene , Wetstein Berish , Anderson Andrew , Konopasky Abigail , Durning Steven 
Published: January 2022

Background: This study sought to explore the relationship between semantic competence (or dyscompetence) displayed during “think-alouds” performed by resident and attending physicians and clinical reasoning performance. Methods: Internal medicine resident physicians and practicing internists participated in think-alouds performed after watching videos of typical presentations of common diseases in internal medicine. The think-alouds were evaluated for the presence of semantic competence and dyscompetence and these results were correlated with clinical reasoning performance. Results: We found that the length of think-aloud was negatively correlated with clinical reasoning performance. Beyond this finding, however, we did not find any other significant correlations between semantic competence or dyscompetence and clinical reasoning performance. Conclusions: While this study did not produce the previously hypothesized findings of correlation between semantic competence and clinical reasoning performance, we discuss the possible implications and areas of future study regarding the relationship between semantic competency and clinical reasoning performance.
Separated by a Common Language: How the Nature of Code Differences Shapes Communication Success and Code Convergence
Authors: Koçak Özgecan , Puranam Phanish 
Published: January 2022

Coordinated action within and beween organizations is easier when individuals share communication codes—mappings between stimuli and labels. Because codes are specific to the groups within which they arise as conventions, collaboration across organizational units that have developed their own distinctive codes is often difficult. However, not all code differences are equal in their implications for communication difficulty and the capacity of individuals starting out with different codes to develop a shared code. Using computational models, we develop a theory about the nature of differences in initial communication codes and how they impact convergence on a common code. Our results show that the difficulty of code convergence lies not as much in learning new codes as in unlearning existing ones. The most severe challenges to communication stem from “code clashes” where codes contain different mappings between the same labels and stimuli. Furthermore, clashes that arise when agents have developed their individual codes in different task environments but draw on a common set of labels are likely to be the hardest to recover from, reflecting the perils of being “separated by a common language.” This paper was accepted by Lamar Pierce, organizations.
High-precision displacement measurement algorithm based on a depth fusion
of grating projection pattern
Authors: Yu Hai , Wan Qiuhua , Lu Xinran , Du Yingcai , Liang Lihui 
Published: January 2022

Displacement measurement based on an image recognition algorithm has more advantages in the field of displacement measurement. Due to the uncertainty of image location, the accuracy of the displacement measurement algorithm studied in the previous stage is limited. To improve the accuracy of image-type displacement measurement, a high-precision displacement measurement algorithm based on depth fusion of the grating projection pattern is proposed. First, a line-scan image sensor and parallel light source are placed on both sides of the calibration grating. The marking pattern on the calibration grating is projected onto the image sensor through illumination of the parallel light source to realize the projection imaging. Then, the centroid algorithm is used to calculate the centroid of each line in the collected image, and the mean value of the centroid group is determined. Finally, a linear function is used to fit multiple centroids to calculate the endpoints of the subdivision region, and the subdivision operation is carried out according to a ratio algorithm. To test the performance of the proposed algorithm, a linear displacement measurement device with a 250 mm range and an angular displacement measurement device with a 100 mm diameter grating are both used for experiments. After testing, the linear measurement accuracy of the proposed algorithm is improved from 4.63 to 1.26 µm, and the angular displacement measurement accuracy is enhanced from 8.87 to

2.88

′
′

. The research in this paper provides a theoretical basis for high-performance displacement measurement.
Establishing laboratory-specific reference intervals for TSH and fT4 by use of the indirect Hoffman method
Authors: Płaczkowska Sylwia , Terpińska Małgorzata , Piwowar Agnieszka 
Published: January 2022

Background
The results of examinations of laboratory parameters are the basis of appropriate medical decisions. The availability of reliable and accurate reference intervals (RIs) for each laboratory parameter is an integral part of its appropriate interpretation. Each medical laboratory should confirm their RIs. Up-to-date reference intervals for thyroid function hormones are still a matter of ongoing controversy. The aim of the study was the application of the indirect Hoffman method to determine RIs for TSH and fT4 based on the large data pools stored in laboratory information systems and the comparison of these RIs to generally used RIs.

Material and methods
The TSH and fT4 routine examination results of hospitalized and outpatient populations were collected over five years (2015–2019), and reference limits were established by the improved Hoffmann method after the exclusion of outliers. Comparative verification of established RIs was conducted with the RIs values provided by test manufacturers and literature data.

Results
Various RIs were observed in different age groups in the examined populations. For TSH, RIs varied between different age groups, with a narrower range of RIs in the studied adult population and a shift of both reference boundaries toward higher values in comparison to manufacturers’ data among children. RIs estimated for fT4 were very similar to the manufacturer and literature data.

Conclusion
Thyroid hormone levels change during a person’s lifetime and vary between sexes, but this difference does not always influence the clinical interpretation of laboratory results in the context of RIs. The use of indirect methods is justified due to the ease and low cost of their application.
Know your enemy: Application of ATR-FTIR spectroscopy to invasive species control
Authors: Holden Claire Anne , Bailey John Paul , Taylor Jane Elizabeth , Martin Frank , Beckett Paul , McAinsh Martin 
Published: January 2022

Extreme weather and globalisation leave our climate vulnerable to invasion by alien species, which have negative impacts on the economy, biodiversity, and ecosystem services. Rapid and accurate identification is key to the control of invasive alien species. However, visually similar species hinder conservation efforts, for example hybrids within the Japanese Knotweed complex.We applied the novel method of ATR-FTIR spectroscopy combined with chemometrics (mathematics applied to chemical data) to historic herbarium samples, taking 1580 spectra in total. Samples included five species from within the interbreeding Japanese Knotweed complex (including three varieties of Japanese Knotweed), six hybrids and five species from the wider Polygonaceae family. Spectral data from herbarium specimens were analysed with several chemometric techniques: support vector machines (SVM) for differentiation between plant types, supported by ploidy levels; principal component analysis loadings and spectral biomarkers to explore differences between the highly invasiveReynoutria japonicavar.japonicaand its non-invasive counterpartReynoutria japonicavar.compacta; hierarchical cluster analysis (HCA) to investigate the relationship between plants within the Polygonaceae family, of theFallopia,Reynoutria,RumexandFagopyrumgenera.ATR-FTIR spectroscopy coupled with SVM successfully differentiated between plant type, leaf surface and geographical location, even in herbarium samples of varying age. Differences betweenReynoutria japonicavar.japonicaandReynoutria japonicavar.compactaincluded the presence of two polysaccharides, glucomannan and xyloglucan, at higher concentrations inReynoutria japonicavar.japonicathanReynoutria japonicavar.compacta. HCA analysis indicated that potential genetic linkages are sometimes masked by environmental factors; an effect that can either be reduced or encouraged by altering the input parameters. Entering the absorbance values for key wavenumbers, previously highlighted by principal component analysis loadings, favours linkages in the resultant HCA dendrogram corresponding to expected genetic relationships, whilst environmental associations are encouraged using the spectral fingerprint region.The ability to distinguish between closely related interbreeding species and hybrids, based on their spectral signature, raises the possibility of using this approach for determining the origin of Japanese knotweed infestations in legal cases where the clonal nature of plants currently makes this difficult and for the targeted control of species and hybrids. These techniques also provide a new method for supporting biogeographical studies.
COVID-19 outbreaks in nursing homes: A strong link with the coronavirus spread in the surrounding population, France, March to July 2020
Authors: Rabilloud Muriel , Riche Benjamin , Etard Jean François , Elsensohn Mad-Hélénie , Voirin Nicolas , Bénet Thomas , Iwaz Jean , Ecochard René , Vanhems Philippe 
Published: January 2022

BackgroundWorldwide, COVID-19 outbreaks in nursing homes have often been sudden and massive. The study investigated the role SARS-CoV-2 virus spread in nearby population plays in introducing the disease in nursing homes.Material and methodsThis was carried out through modelling the occurrences of first cases in each of 943 nursing homes of Auvergne-Rhône-Alpes French Region over the first epidemic wave (March-July, 2020). The cumulative probabilities of COVID-19 outbreak in the nursing homes and those of hospitalization for the disease in the population were modelled in each of the twelveDépartementsof the Region over period March-July 2020. This allowed estimating the duration of the active outbreak period, the dates and heights of the peaks of outbreak probabilities in nursing homes, and the dates and heights of the peaks of hospitalization probabilities in the population. Spearman coefficient estimated the correlation between the two peak series.ResultsThe cumulative proportion of nursing homes with COVID-19 outbreaks was 52% (490/943; range: 22–70% acc. Département). The active outbreak period in the nursing homes lasted 11 to 21 days (acc. Département) and ended before lockdown end. Spearman correlation between outbreak probability peaks in nursing homes and hospitalization probability peaks in the population (surrogate of the incidence peaks) was estimated at 0.71 (95% CI: [0.66; 0.78]).ConclusionThe modelling highlighted a strong correlation between the outbreak in nursing homes and the external pressure of the disease. It indicated that avoiding disease outbreaks in nursing homes requires a tight control of virus spread in the surrounding populations.
Inclusion at universities: Psychometric properties of an inclusive management scale as perceived by students
Authors: Solis-Grant María José , Espinoza-Parçet Camila , Sepúlveda-Carrasco Cristóbal , Pérez-Villalobos Cristhian , Rodríguez-Núñez Iván , Pincheira-Martínez Cristian , Gómez-Varela Juan Pablo , Aránguiz-Ibarra Daniela 
Published: January 2022

Introduction
During the last century, the inclusion of all kinds of diversity became a social imperative in all social spaces but above all in some institutions such as the educational ones. Among these, inclusion has been least studied in the tertiary education organizations. This communication proposes and evaluates the psychometric properties of a new instrument, named Inclusive Management in Tertiary Institutions Scale (IMTIS), to assess inclusive management in universities.

Method
The researchers used a quantitative research model through survey. We based on the Index for Inclusion to design the IMTIS. We first submitted it to the assessment of experts. Then we applied the resulting version in an online survey including a sample of 1557 students from two universities and 121 different undergraduate careers. A panel of experts judged the content validity of the instrument. Participants answered the IMTIS after informed consent. We used confirmatory factor analysis to assess the construct validity of the instrument. We also evaluated the reliability of the measurements.

Results
From a kit of 33 originally proposed items, we obtained a version of 22 items with CVR between 0.60 and 1.00, and a IVC = 0.78. The confirmatory factor analysis showed that the six-factor solution had a better adjustment than the one and three factors solutions (RMSEA = 0.059; CFI = 0.947; TLI = 0.937). The McDonald ω coefficients were between 0.864 and 0.922.

Conclusion
The results deliver evidence that supports the validity and reliability of the IMTIS measurements to carry out research and diagnosis of inclusive management in higher education institutions.
Characteristics of severely malnourished under-five children immunized with Bacillus Calmette-Guérin following Expanded Programme on Immunization schedule and their outcomes during hospitalization at an urban diarrheal treatment centre, Bangladesh
Authors: Ackhter Mst. Mahmuda , Shahid Abu Sadat Mohammad Sayeem Bin , Ahmed Tahmeed , Palit Parag , Parvin Irin , Islam Md. Zahidul , Alam Tahmina , Shaima Shamsun Nahar , Shahrin Lubaba , Afroze Farzana , Sarmin Monira , Islam Shoeb Bin , Akhtar Zubair , Chisti Mohammod Jobayer , Chowdhury Fahmida 
Published: January 2022

Background
Bacillus Calmette-Guérin (BCG) vaccination has recently been found to have beneficial effects among children infected other than Mycobacterium tuberculosis. Due to the paucity of data on the outcomes of children who had successful BCG vaccination following Expanded Programme on Immunization (EPI) schedule, we aimed to investigate the characteristics of such children and their outcomes who were hospitalized for severe malnutrition.

Methods
A prospective observational study was conducted to determine the viral etiology of pneumonia in severely malnourished children those were admitted to the Dhaka Hospital of International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b) between April 2015 and December 2017, constituted the study population. Using a case-control design for the analysis, children having BCG vaccination prior hospital admission were treated as cases (n = 611) and those without vaccination, constituted as controls (n = 83). Bi-variate analysis was conducted using socio-demographic, clinical, laboratory, and treatment characteristics on admission and outcomes during hospitalization. Finally, log-linear binomial regression analysis was done to identify independent impact of BCG vaccination.

Results
The cases more often presented with older age, have had lower proportion of maternal illiteracy, higher rate of breastfeeding, severe wasting and lower rate of hypoglycemia, compared to the controls. The cases were also found to have lower risk of severe sepsis and deaths, compared to the controls (for all, p<0.05). However, in log-linear binomial regression analysis, after adjusting for potential confounders, BCG vaccination following EPI schedule (RR:0.54; 95%CI = 0.33–0.89; p = 0.015) and breastfeeding (RR:0.53; 95%CI = 0.35–0.81; p = 0.003) were found to be protective for the development of severe sepsis.

Conclusion
BCG vaccination and breastfeeding were found to be protective for the development of severe sepsis in hospitalized severely malnourished under-five children which underscores the importance of continuation of BCG vaccination at birth and breastfeeding up to two years of age.
Fusobacterium nucleatum and Bacteroides fragilis detection in colorectal tumours: Optimal target site and correlation with total bacterial load
Authors: Rye Marie S. , Garrett Kerryn L. , Holt Robert A. , Platell Cameron F. , McCoy Melanie J. 
Published: January 2022

Background
Mucosal infiltration by certain bacterial species may contribute to the development and progression of colorectal cancer (CRC). There is considerable variation in reported detection rates in human CRC samples and the extent to which bacterial infiltration varies across regions of the primary tumour is unknown. This study aimed to determine if there is an optimal site for bacterial detection within CRC tumours.

Methods
Presence of target bacterial species was assessed by quantitative real-time PCR (qPCR) in 42 human CRC tumours. Abundance in primary tumour regions, normal epithelium and at metastatic sites was investigated in an expanded cohort of 51 patients. Species presence/absence was confirmed by diversity profiling in five patients. Correlation with total bacterial load and clinicopathological features was assessed.

Results
Fusobacterium nucleatum and Bacteroides fragilis were detected in tumours from 43% and 24% of patients, respectively (17% positive for both species). The optimal detection site was the tumour luminal surface (TLS). Patients testing positive at the TLS frequently tested negative at other sites, including central tumour and invasive margin. F. nucleatum was detected at a higher frequency in tumour versus normal epithelium (p < 0.01) and was associated with more advanced disease (p = 0.01). Detection of both species correlated with total bacterial load. However, corroboration of qPCR results via diversity profiling suggests detection of these species may indicate a specific microbial signature.

Conclusions
This study supports a role for F. nucleatum in CRC development. Presence of F. nucleatum and B. fragilis varies across primary tumour regions, with the TLS representing the optimal site for bacterial detection.