bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Case Report VP shunt in Non Communicating Hydrocephalus due to Intracerebral Hemorrhage
Authors: Muharam Firman , Hanafi Dahlan Rully , Estethia Ompusunggu Seyline 
Published: November 2022

Stroke is one of the top three cause of death and disability globally. Approximately, only 10% to 15% of first-ever stroke are intracerebral hemorrhages (ICHs), but the rates of disability and death are significantly higher. Hydrocephalus may occur in more than 50% of patients with intraventricular hemorrhage (IVH), which is secondary to ICH. Intraventricular hemorrhage (IVH), an accumulation of blood to ventricles that may be cause by extension of ICH, occurs in up to 50% of patients with primary ICH. Hydrocephalus itself may serves as a predictor of poor outcome after ICH.1,2,3
A 71 years old male came to the hospital with the complaint of loss of consciousness, difficulty in communicating, and weakness of extremities on the left side of the body since 12 hours ago. The complaint was preceded by headache that did not alleviate with medication since 1 day before admission and there was history of slurred speech. A head CT scan without contrast was done and the result showed an intracerebral hemorrhage and a suggestive obstructive hydrocephalus. The patient was diagnosed noncommunicating hydrocephalus due to spontaneous intracerebral haemorrhage (ICH) at the right thalamus with intraventricular haemorrhage due to suspect hypertension with differential diagnosis of cerebral amyloid angiopathy with emergency hypertension. The patient was advised to underwent an emergency VP shunt placement.
Implantation of a ventriculoperitoneal (VP) shunt is the most widely used treatment of hydrocephalus. Considered to be a major privonce of neurosurgery, it accounts for 70.000 hospital admission in the US. Even though, VP shunting of CSF reduces the morbidity and mortality of post-hemorrhagic. hydrocephalus, it is associated with potential complications requiring multiple surgical procedures, as well as shunt revision due to its failure during the patient’s lifetime.4
A Case Report The Evaluation of Malondialdehyde Level on Acne Vulgaris Treatment
Authors: Muhammad Ridlo  , Jusuf Nelva K. 
Published: November 2022

Abstract: Acne vulgaris (AV) is a multifactorial disease of the pilosebaceous unit with varying degrees of severity, recurrent and characterized by polymorphic lesions. Recent studies have found that the etiopathogenesis of AV is caused by oxidative stress. Each factor that causes AV is interrelated and is under the control of hormones and immunity. Measurement of malondialdehyde (MDA) level in the blood becomes a biological marker or an indicator of cell and tissue damage caused by oxidative stress. Case: A 23-years-old female private employee visited the clinic for multiple comedones and papulopustular lesions scattered over cheeks, nose, and chin that spread to the whole face four months ago. There were multiple comedones, papules, pustules, nodules on the maxillary, nasalis, left and right zigomatic, mentalis and frontalis region. We also found multiple scars on the left and right buccal. She was diagnosed with Severe AV. Serum MDA level was measured according to the enzyme-linked immunosorbent assay (ELISA) method before and after therapy. She was treated with doxycycline 100 mg, 0.025% tretinoin cream, 5% benzoyl peroxide, 1.2% clindamycin gel, and broadspectrum sunscreen with SPF 50. Result: After eight weeks of treatment, there were noticeable improvements in acne lesions and overall healthier-looking skin. Serum MDA levels are decreased (22.6 nmol/ml to 17.9 nmol/ml) as the impact of the therapy.
Keyword: Acne Vulgaris, Malondialdehyde, Oxidative Stress
Analisis pengelolaan sampah dengan prinsip 3R sebagai upaya penurunan volume sampah pada ibu rumah tangga di Kelurahan Labuhan Deli
Authors: Rahim Zikrina Irmaya , Indirawati Sri Malem 
Published: November 2022

Permasalahan lingkungan yang menjadi isu nasional adalah permasalahan sampah. Upaya penurunan volume sampah ditingkat rumah tangga dapat dilakukan dengan penerapan prinsip 3R (Reduce, Reuse dan Recycle) dengan melibatkan partisipasi ibu rumah tangga. Penelitian ini dilakukan untuk mengetahui implementasi pengelolaan sampah dengan prinsip 3R sebagai upaya penurunan volume sampah pada ibu rumah tangga di Kelurahan Labuhan Deli. Metode dalam penelitian ini merupakan survei yang bersifat deskriptif untuk melihat gambaran pengelolaan sampah dengan prinsip 3R pada ibu rumah tangga di Kelurahan Labuhan Deli. Hasil penelitian menunjukkan responden merupakan ibu rumah tangga berumur 55-56 tahun (37,8%), pendidikan terakhir SD (51%), pendapatan keluarga di bawah Rp. 3.000.000 (63,3%), suku melayu (72,4%) dan memiliki jumlah anggota keluarga <5 orang (77,6%) dengan timbulan sampah rumah tangga yang dihasilkan dalam 6 hari adalah 397,5 Kg atau setiap harinya dihasilkan sampah rumah tangga 0,676 Kg/hari dan 0,166 Kg/orang/hari dengan jenis sampah organik sebanyak 90% dan sampah anorganik 10%. Komposisi sampah terbanyak adalah sampah makanan sebanyak 83,3%. Pengelolaan sampah dengan prinsip reduce pada sebagian besar ibu rumah tangga masuk kategori rendah yaitu 75 ibu rumah tangga (76,5%), pengelolaan sampah dengan prinsip reuse pada sebagian ibu rumah tangga masuk kategori sedang yaitu 46 ibu rumah tangga (46,9%), pengelolaan sampah dengan prinsip recycle pada sebagian besar ibu rumah tangga masuk kategori rendah yaitu 96 ibu rumah tangga (98%), dan pengelolaan sampah dengan prinsip 3R pada sebagian besar ibu rumah tangga masuk kategori rendah yaitu 88 ibu rumah tangga (89,8%). Kemudian hampir semua ibu rumah tangga tidak mengetahui adanya Peraturan Daerah dan Peraturan Wali Kota Medan berkaitan dengan pengelolaan Sampah Rumah serta adanya denda sebesar 10.000.000 atau kurungan penjara selama 3 bulan bagi setiap orang yang membuang sampah sembarangan.
Hubungan tingkat religiusitas dan tingkat kecemasan mahasiswa keperawatan selama pandemi COVID-19
Authors: Tumanggor Roxsana Devi , Nasution Nikmal Hasanah 
Published: November 2022

Mahasiswa menunjukkan beberapa gejala psikologis selama Pandemi COVID-19, seperti rasa takut terinfeksi COVID-19 dan kecemasan. Riset menunjukkan bahwa religiusitas adalah faktor penting yang harus di integrasikan ke dalam intervensi intervensi keperawatan untuk mengurangi risiko faktor kecemasan maupun dampak psikologis lainnya. Penelitian ini adalah penelitian cross-sectional yang bertujuan untuk menganalisis hubungan antara tingkat religiusitas dan tingkat kecemasan mahasiswa selama Pandemi. Berdasarkan teknik proportional stratified random sampling didapatkan 87 orang mahasiswa keperawatan sebagai sampel penelitian. Instrumen yang diujikan dalam penelitian ini adalah The Centrality of Religiosity Scale (CRS) dan kuisioner kecemasan terhadap COVID-19 yang sudah melalui uji validitas dan reliabilitas. Data dianalisis dengan uji korelasi Pearson untuk analisis hubungan kedua variabel dan menentukan distribusi frekwensi karakteristik sampel yang diteliti. Hasil penelitian ini menunjukkan bahwa lebih dari 90% sampel adalah perempuan, dan tiga diantaranya pernah terinfeksi dengan COVID-19. Berdasarkan hasil uji statistik untuk mencari hubungan dengan uji Korelasi Pearson menunjukkan hubungan kuat antara religiusitas dan kecemasan terhadap COVID-19. Hasil analisis statistik diperoleh koefisien korelasi -0,404 dengan P 0,00<0,05. Nilai koefisien korelasi menunjukkan terdapat hubungan negatif yang signifikan, artinya semakin tinggi religiusitas maka semakin rendah kecemasan terhadap COVID-19.
SHARIAH AND MEDICAL MEASURES TO PREVENT THE EMERGING CORONA (COVID-19): AN ANALYTICAL STUDY
Authors: Abdul Rab Muneer Ali , Hasan Baidar Mohammed Mohammed , Gunardi Setiyawan , Hoque Mesbahul 
Published: November 2022

The affliction of worshippers is a fixed Sunnah that has been passed by Allah in all of His creation. Allah has in his Noble Book, reported many types of calamities that plague His servants, and from this affliction: epidemics such as plague. People have known epidemics and plagues since ancient times, and it still applies to people to this day, all people witnessed Covid-19. Allah would not send down a disease to His servants except that He sent down a cure for it, Therefore, it is imperative for the Islamic nation to follow the instructions and measures urged by the Islamic religion, especially since medical practitioners have not found any effective treatment to prevent the infection. Even though it has reached the level of vaccines, but the transmission of infection has not been prevented. Therefore, these measures and instructions remain the mainstay of prevention and protection from it. This research aims to clarify the Shariah and medical preventive measures (Covid-19), and study them as an analytical study. To achieve this goal; the researcher followed the inductive and analytical approach, The researcher concluded that among the Shariah measures to prevent epidemics are: quarantine, fleeing from lepers, avoiding handshakes, purification, placing a hand or a garment over the mouth when sneezing, fermentation of vessels and potting of pots, abstinence from immorality and disobedience, enjoining good and forbidding evil, and adherence to supplications and remembrances. Similarly, among the medical measures to prevent the corona epidemic are the following: taking care of hygiene, washing hands, using disinfectants, wearing masks and gloves, social distancing, and applying home quarantine for those infected with colds, avoid direct contact with them.
Keywords: Shariah, medica, measures, protection, (Covid-19).
THE REGULATION OF HALAL LABEL IN NON-PACKAGED FAST-FOOD PRODUCTS IN INDONESIA ONLINE BUSINESS
Authors: Azizah Siti Nur 
Published: November 2022

This research aims to understand the implementation of Halal certification regulation and the responsibility of the producer along with the authority of halal certification institution toward the non-packaged, ready-to-eat products in Indonesia. This research used a normative juridical method with a qualitative approach to observe the regulations related to product halalness. This result showed that halal label strive to guarantee the ingredients and the production process from the beginning until the end. The production tools should be divided between tools used for halal and non-halal products and storage. The implementation of halal labeling on non-packaged ready-to-eat products can be pushed by some factors, including having a national campaign program, consistent in halal certification procedure, providing access to SMEs actors for the easy and affordable halal certification process, and cooperation between the product owner and online application to give halal certification with the operational business requirements. Therefore the synergy of all parties in the implementation and supervision of halal certification is needed to create a significant change in online business in Indonesia.
Gestão de conformidade (compliance): reflexões sobre o impacto na estrutura e desempenho da governança
Authors: Vasconcelos Yumara Lúcia , Soares Amanda Paulino 
Published: November 2022

A elaboração deste artigo, apresenta os resultados de uma pesquisa bibliográfica cujo objetivo geral foi apresentar reflexões sobre o impacto dos programas de compliance e gestão de conformidade sobre a estrutura e desempenho da governança, mapeando os fatores de sucesso. Selecionadas as obras que constituíram as fontes revisadas, realizou-se a análise de conteúdo orientada pelas seguintes categorias temáticas estruturantes: alicerces da governança corporativa, compliance e interconexão; aspectos estruturantes da gestão de conformidade (dimensão instrumental); mitigação de risco; interface entre os instrumentos gerenciais e o aparato de controle interno. Resultou deste apanhamento a constatação, em uma perspectiva instrumental, da relação de continência entre os conceitos governança corporativa, gestão de conformidade e os Programa de compliance e integridade. Documentos diretivos, políticas, controles internos, processos procedimentos e protocolos são produtos humanos. A aderência às diretivas organizacionais, mais que respostas condicionadas, precisam produzir adesão consciente e espontânea. Quanto maior a for a adesão e engajamento organizacional aos comandos dirigentes, mais efetivos serão os controles internos, menor será o número de ocorrências de comportamentos desviantes, ou mesmo, de ilícitos. Pelos argumentos apresentados, restou evidente a importância desses Programas, ou em sentido expandido, da gestão de conformidade, para a instituição de um ambiente de governança responsivo, eficiente, eficaz e socialmente responsável.
Perbandingan antara GAAP Indonesia dan GAAP Italia
Authors: Christian Natalis , Angelica Serly , Tanwijaya Rachel 
Published: November 2022

Indonesia and Italy have been adopting IFRS in their national accounting standards. However, Indonesia’s GAAP is different from Italy’s GAAP. Hence, financial information users must be educated and understand both countries’ GAAP to interpret the financial report. The purpose of the research is to compare Indonesia’s GAAP and Italy’s GAAP. The research method uses descriptive qualitative analysis. The source of data is based on non-numeric secondary data. The research result shows eight factors that affect accounting development in Italy. There are also differences between Indonesia’s GAAP and Italy’s GAAP. Those differences are related to financial reports presentation, interests, dividends, goodwill, consolidated financial statements, and inventories.

Keywords: Accounting standard, OIC, SAK, Italy, Indonesia

Abstrak
Indonesia dan Italia telah menerapkan IFRS pada standar akuntansi nasional negara masing-masing. Akan tetapi, GAAP Indonesia dengan GAAP Italia memiliki perbedaan dalam metode pencatatan akuntansi. Oleh sebab itu, untuk dapat memahami laporan keuangan yang disusun berdasarkan GAAP masing-masing negara, pengguna laporan keuangan perlu memiliki pemahaman dan menguasai pencatatan GAAP kedua negara tersebut. Tujuan dari penelitian ini adalah melakukan perbandingan antara GAAP Indonesia dan GAAP Italia. Metode penelitian yang diterapkan merupakan metode deskriptif kualitatif. Data penelitian yang digunakan bersifat data sekunder non numerik. Hasil dari penelitian ini menjukkan adanya 8 faktor yang memengaruhi perkembangan akuntansi di Italia. Selain itu, terdapat perbedaaan antara standar akuntansi Indonesia dan standar akuntansi Italia. Perbedaan tersebut terdiri dari segi pelaporan keuangan, bunga, dividen, goodwill, laporan keuangan konsolidasi dan persediaan.

Kata kunci: Standar Akuntansi, OIC, SAK, Italia, Indonesia
Pengaruh Bi Rate, IHK, Dan JUB (M2) Terhadap NAB Reksadana Pada Masa Pandemi Covid-19 di Indonesia
Authors: Nurjannah Alfira , Hartini Titin , Azwari Peny Cahaya 
Published: November 2022

The development of Mutual Funds is moving in a positive direction, with Net Asset Values ​​that continue to increase even during the Covid-19 pandemic. Several studies state that factors can affect the Net Asset Value of Mutual Funds, including the BI Rate, Consumer Price Index (CPI), and Money Supply (JUB). The methodology used in this study is quantitative in the form of data analysis techniques that were tested statistically using the classical assumption test and multiple linear regression. The data used is with a monthly time series from March 2020 to March 2022, which is the era of the COVID-19 pandemic in Indonesia. The data is processed using Eviews-12. Based on the research results, the Net Asset Value (NAV) of Mutual Funds is simultaneously influenced by the BI Rate, CPI, and JUB (M2). However, partially NAV of Mutual Funds is negatively and significantly affected by the BI Rate. In contrast, CPI affects NAV of Mutual Funds negatively but not significantly, then JUB affects NAV of Mutual Funds positively but not significantly.

Keywords: BI Rate, Consumer Price Index, Money Supply, Net Asset Value

Abstrak
Perkembangan Reksadana bergerak kearah positif dengan Nilai Aktiva Bersih yang terus meningkat meskipun dalam masa pandemi Covid-19. Beberapa penelitian menyatakan bahwa terdapat faktor-faktor yang dapat mempengaruhi Nilai Aktiva Bersih Reksadana diantaranya yaitu BI Rate, Indeks Harga Konsumen(IHK), dan Jumlah Uang Beredar(JUB). Metodologi yang digunakan pada penelitian ini adalah kuantitatif berupa teknik analisa data yang diuji statistik menggunakan uji asumsi klasik serta regresi linear berganda. Data yang digunakan adalah data dengan deret waktu perbulan, mulai bulan Maret 2020 hingga Maret 2022 yang merupakan era pandemic covid-19 di Indonesia data tersebut diolah menggunakan Eviews-12. Berdasarkan hasil penelitian, Nilai Aktiva Bersih (NAB) Reksadana secara simultan dipengaruhi oleh BI Rate, IHK, dan JUB (M2). Namun dalam secara parsial NAB Reksadana dipengaruhi secara negatif dan signifikan oleh BI Rate, sedangkan IHK mempengaruhi NAB Reksadana secara negatif tetapi tidak signifikan, kemudian JUB mempengaruhi NAB Reksadana secara positif namun tidak signifikan.

Kata Kunci: BI Rate, Indeks Harga Konsumen, Jumlah Uang Beredar, Nilai Aktiva Bersih
Research on skeletal muscle impact injury using a new rat model from a bioimpact machine
Authors: Liu Jun , Liao Zhikang , Wang Jingkun , Xiang Hongyi , Zhu Xiyan , Che Xingping , Tang Yuqian , Xie Jingru , Mao Chengyi , Zhao Hui , Xiong Yan 
Published: November 2022

Introduction: Skeletal muscle impact injury occurs frequently during sports, falls, and road traffic accidents. From the reported studies on skeletal muscle injury, it is difficult to determine the injury parameters. Therefore, we developed a new model of gastrocnemius impact injury in rats with a bioimpact machine, with which the experimental operation could be conducted in feasibility from the recorded parameters. Through this novel model, we study the skeletal muscle impact injury mechanisms by combining temporal and spatial variation.Methods: The gastrocnemius of anesthetized rats was injured by a small pneumatic-driven bioimpact machine; the moving speed and impact force were determined, and the whole impact process was captured by a high-speed camera. We observed the general condition of rats and measured the changes in injured calf circumference, evaluating calf injuries using MRI, gait analysis system, and pathology at different times after the injury.Results: The gastrocnemius was injured at an impact speed of 6.63 m/s ± 0.25 m/s and a peak force of 1,556.80 N ± 110.79 N. The gait analysis system showed that the footprint area of the RH limb decreased significantly on the first day and then increased. The calf circumference of the injured limb increased rapidly on the first day post-injury and then decreased in the next few days. MRI showed edema of subcutaneous and gastrocnemius on the first day, and the area of edema decreased over the following days. HE staining showed edema of cells, extensive hyperemia of blood vessels, and infiltration of inflammatory cells on the first day. Cell edema was alleviated day by day, but inflammatory cell infiltration was the most on the third day. TEM showed that the sarcoplasmic reticulum was dilated on the first day, the mitochondrial vacuolation was obvious on the second day, and the glycogen deposition was prominent on the fifth day.Conclusion: In our experiment, we developed a new and effective experimental animal model that was feasible to operate; the injured area of the gastrocnemius began to show “map-like” changes in the light microscope on the third day. Meanwhile, the gastrocnemius showed a trend of “edema-mitochondrial vacuolation-inflammatory cell aggregation” after impact injury.
Machine learning outperforms traditional logistic regression and offers new possibilities for cardiovascular risk prediction: A study involving 143,043 Chinese patients with hypertension
Authors: Xi Yang , Wang Hongyi , Sun Ningling 
Published: November 2022

IntroductionIdentifying people at risk of cardiovascular diseases (CVD) is a cornerstone of preventive cardiology. We developed machine learning (ML) algorithms and investigated their performance in predicting patients’ current CVD risk (coronary heart disease and stroke in this study).Materials and methodsWe compared traditional logistic regression (LR) with five ML algorithms LR with Elastic-Net, Random Forest (RF), XGBoost (XGB), Support Vector Machine, Deep Learning, and an Ensemble model averaging predictions from RF, XGB, and Deep Learning for CVD risk prediction using pre-existing patient-level data from a multi-center, cross-sectional study (the Microalbuminuria Screening in Hypertensive Patients Project initiated by the China International Exchange and Promotive Association for Medical and Healthcare) that enrolled 143,043 patients with hypertension from 600 tertiary, secondary, or community hospitals. Each of the five ML algorithms incorporated 18 variables, such as demographics, examinations, comorbidities, and treatment regimens, and were trained and evaluated using 5-fold cross-validation. Predictive accuracy was assessed by the area under the receiver operating curve (AUROC).ResultsPatients’ mean age was 62 ± 12 years and 57% were men. Advanced ML algorithms outperformed the traditional LR model. Particularly, the Ensemble model had superior discrimination with an AUROC of 0.760 than LR (AUC = 0.737) and other tested models.ConclusionWe establishes an Ensemble model that shows better performance in predicting patients’ current CVD risk using routine information compared to the traditional LR model. ML can help physicians design follow-up plans with more accurate results, offering new possibilities for short-term risk prediction and early detection. Further, ML models can be trained with longitudinal data and used to predict long-term CVD risks, thereby informing CVD prevention.
Clinical significance of right ventricular–pulmonary arterial coupling in patients with tricuspid regurgitation before closure of atrial septal defect
Authors: Lee Seon Hwa , Shin Yu Rim , Kim Dae-Young , Seo Jiwon , Cho Iksung , Lee Sak , Kim Jung Sun , Hong Geu-Ru , Ha Jong-Won , Shim Chi Young 
Published: November 2022

BackgroundFunctional tricuspid regurgitation (TR) usually decreases after atrial septal defect (ASD) closure; however, it may persist and cause heart failure that requires treatment. We aimed to investigate clinical and echocardiographic factors predicting persistent TR after ASD closure.MethodsAmong 348 adults who underwent isolated ASD closure between January 2010 and September 2020, 91 (26.1%) patients with significant TR (at least moderate degree) before ASD closure were included. Persistent TR was defined as significant TR on echocardiography at 6 months to 1 year after ASD correction. We comprehensively analyzed the echocardiogram before ASD closure, including speckle-tracking imaging. Right ventricular (RV)–pulmonary arterial (PA) (RV–PA) coupling was assessed by the ratio of RV global longitudinal strain (RV GLS) and tricuspid annular S' velocity to PA systolic pressure (PASP).ResultsPersistent TR was observed in 22 (24.2%) patients. Patients with persistent TR were significantly older and had larger TR jet areas and lower RV–PA coupling parameters than those without persistent TR. On multivariable regression, persistent TR was independently associated with age [odds ratio (OR) 1.07, 95% confidence interval (CI) 1.01–1.14, p = 0.030) and |RV GLS|/PASP (OR 0.001, 95% CI 0.00–0.017, p = 0.012). ROC curves analysis showed that |RV GLS|/PASP's best cut-off for persistent TR was 0.46 (cut-off 0.46, the area under the curve 0.789, p &lt; 0.001).ConclusionPersistent TR after ASD closure is not rare. Old age and RV–PA uncoupling could be associated with persistent TR after ASD closure. In older patients with abnormal RV–PA coupling, careful evaluation and concomitant or subsequent TR intervention may be considered.