bluuebunny/crossref_metadata_2025_split huggingface dataset:
PriSUD-Nordic—Diagnosing and Treating Substance Use Disorders in the Prison Population: Protocol for a Mixed Methods Study
Authors: Bukten Anne , Lokdam Nicoline Toresen , Skjærvø Ingeborg , Ugelvik Thomas , Skurtveit Svetlana , Gabrhelík Roman , Skardhamar Torbjørn , Lund Ingunn Olea , Havnes Ingrid Amalia , Rognli Eline Borger , Chang Zheng , Fazel Seena , Friestad Christine , Hesse Morten , Lothe Johan , Ploeg Gerhard , Dirkzwager Anja J E , Clausen Thomas , Tjagvad Christian , Stavseth Marianne Riksheim 
Published: March 2022

Background
A large proportion of the prison population experiences substance use disorders (SUDs), which are associated with poor physical and mental health, social marginalization, and economic disadvantage. Despite the global situation characterized by the incarceration of large numbers of people with SUD and the health problems associated with SUD, people in prison are underrepresented in public health research.

Objective
The overall objective of the PriSUD (Diagnosing and Treating Substance Use Disorders in Prison)-Nordic project is to develop new knowledge that will contribute to better mental and physical health, improved quality of life, and better life expectancies among people with SUD in prison.

Methods
PriSUD-Nordic is based on a multidisciplinary mixed method approach, including the methodological perspectives of both quantitative and qualitative methods. The qualitative part includes ethnographic fieldwork and semistructured interviews. The quantitative part is a registry-based cohort study including national registry data from Norway, Denmark, and Sweden. The national prison cohorts will comprise approximately 500,000 individuals and include all people imprisoned in Norway, Sweden, and Demark during the period from 2000 to 2019. The project will investigate the prison population during three different time periods: before imprisonment, during imprisonment, and after release.

Results
PriSUD-Nordic was funded by The Research Council of Norway in December 2019, and funding started in 2020. Data collection is ongoing and will be completed in the first quarter of 2022. Data will be analyzed in spring 2022 and the results will be disseminated in 2022-2023. The PriSUD-Nordic project has formal ethical approval related to all work packages.

Conclusions
PriSUD-Nordic will be the first research project to investigate the epidemiology and the lived experiences of people with SUD in the Nordic prison population. Successful research in this field will have the potential to identify significant areas of benefit and will have important implications for ongoing policy related to interventions for SUD in the prison population.

International Registered Report Identifier (IRRID)
DERR1-10.2196/35182
Cuerpo de hombre, emociones y afectos en la vulnerabilidad. Impacto psicosocial de la pandemia en la salud de los varones
Authors: Castellanos-Suárez Viviana , Olarte Ramos Carlos Arturo 
Published: March 2022

El presente artículo es el resultado de explorar a partir de una revisión bibliográfica, documental, registrada y sistemática el estado actual del impacto psicosocial de la pandemia por la COVID-19 entre los hombres, a fin de sintetizar ideas, hallazgos y demás información que permitan conocer qué áreas emocionales, afectivas o relacionales se han visto afectadas en los varones, así como los factores que han influido para que estas áreas sean vulneradas. Para ello se determinaron tres ámbitos de impacto: 1) efectos en los estados emocionales y afectivos, 2) efectos relacionales y sociales, y 3) cambios hacia la llamada nueva normalidad. La revisión permitió concluir que mientras los impactos afectivos y emocionales se centran en el incremento de los niveles de estrés, depresión, ansiedad, los impactos relacionales y sociales giran en torno a cambios en los estereotipos de género; entretanto, los cambios asociados a la nueva normalidad aún están difusos y se orientan hacia el fomento de la interdependencia para asegurar la sobrevivencia humana. Se concluye que es necesario impulsar estudios sobre los varones como sujetos o cuerpos más vulnerables físicamente al contagio, validando y visibilizando sus emociones y afectos, así como apuntalar a la deconstrucción de la negación, evasión o postergación de su derecho a la afectividad, a fin de favorecer la salud física, psíquica y mental en la nueva realidad.
La ciencia abierta: desafíos para la construcción de cultura científica en la República Dominicana
Authors: Madé Manuel , Gómez-Valenzuela Víctor 
Published: March 2022

En noviembre de 2021, la UNESCO celebró en París su 41a reunión de la Conferencia General para establecer acuerdos, siendo uno de ellos la ciencia abierta; en este evento la República Dominicana dijo presente y dio su aprobación a esta iniciativa (Presidencia, 2021). La iniciativa de la ciencia abierta implica una gran oportunidad para la democratización de la ciencia y un desafío para los países miembros que acogieron la propuesta, sobre todo porque deben diseñar estrategia en materia de política de ciencia y tecnologías acorde con la filosofía de la ciencia abierta para la rendición de cuentas ante la UNESCO. En este breve ensayo, estaremos abordando algunos aspectos que deben ser considerados para enfrentar los desafíos acaecidos en la apuesta por la ciencia abierta con vista a la construcción de una cultura científica y tecnológica en la República Dominicana.
Identification of Women's Quality of Life Home Business Actors with Influencing Factors
Authors: Andini Thathit Manon , Kurniawati Dini , Alifatin Aini , Hayatin Nur 
Published: March 2022

The basic problem in women's empowerment that has occurred so far is the low participation of women in development. In addition, there are still various forms of discriminatory practices against women.
In the social context, there are still gaps in the roles of men and women (Education, Health and public participation involvement). Susenas data (National Socio-Economic Survey) 2003 shows that the education level of Indonesian women is still low. If there are physical, mental, or social health problems, it can reduce the value of quality of life. When women are busy in fulfilling the family's economy, will their physical, mental and social conditions become healthy? Will their quality of life be maintained when they become the foundation of the family's economy? What are their quality of life indicators? This study aims to determine their quality of life associated with various factors (Health, education, economy, etc.). In this study, the researcher chose to use qualitative methods or descriptive analysis to identify and describe the quality of life of women entrepreneurs at home and the factors that influence them. From the results of the study, it can be seen from the personal data, The women who do home-based businesses are still of productive age, with minimal high school education. Their efforts can generate sufficient income to meet their needs. It can be concluded that the quality of life of the women is good, as well as mental conditions (self-satisfaction, self-motivation). The dominant factors in influencing mothers to run their businesses are educational factors, self-confidence in running their business, self-satisfaction and also feeling healthy, feeling safe.
Risk-Based Post-Marketing Surveillance (RB-PMS) of antimalarial drugs and maternal, neonatal and reproductive health (MNCH) in Mali
Authors: Dembele Ousmane , Coulibaly Seydou Moussa , Cissé Bakary Moussa , Cissé Mody , Dakouo Jacques , Cissé Nana Houmama , Koumaré Benoît Yaranga 
Published: March 2022

Objectives: In a world marked by the increase in chemoresistance leading to the adoption of therapeutic combinations, the advent of generic multi-source drugs, the spread of counterfeiting and substandard drugs, often without active ingredients or falsified active ingredients, a Greater vigilance by pharmaceutical regulatory authorities is needed. Drug Post-Marketing Surveillance (PMS) therefore plays an important role in detecting poor quality products on the market. Risk-Based Post-Marketing Surveillance (RB-PMS) is a new form of PMS that is emerging and was the subject of a recent WHO publication.
Methods: The survey covered certain regions and certain points of sale identified by a Technical Working Group. It aimed to assess the quality of antimalarial and MNCRH drugs available at certain risk distribution levels based on priority sites. The selection of drugs and geographic areas was made using risk-based sampling using the Drug Risk Assessment Tool (MedRS) developed by USP / PQM +.
Results: A total of 242 samples were taken and analyzed according to a risk-based protocol, of which 233 were compliant with a rate of 96% against 9 were non-compliant or 4% (P≤0,05). Non-compliant drugs were mainly from the public sector. We found 69% of the unregistered drugs that consisted mainly of antimalarial drugs and which came from India and China.
Conclusion: In view of the scarcity of resources and its scientific nature, this risk-based sampling and analysis technique (RB-PMS) must be pursued, optimized and made sustainable to ensure health and guarantee access to quality medicines for the health and well-being of populations.
Keywords: Antimalarials, MNCH, Quality Control, RB-PMS.
PENYULUHAN PERBAIKAN SISTEM RONDA MALAM KELILING DI RT 07 DESA KEDUNGHARJO, NGAWI, JAWA TIMUR
Authors: Nikmah Novia Faqihatun 
Published: March 2022

This research aims to restore the night patrol system was stopped RT 07 Kedungharjo village. Â In this research several attempts or the stages in the research are also described in detail. Efforts such as: request for permission to the head of the household, counseling on the importance of night patrols to residents, making a schedule for the night patrol and cleaning the guard post as the final form of the stage this. Â The method used in this research is a stage consisting of 3 stages. Namely the initial stage of preparation for the implementation stage and the final stage of the evaluation of the activities that has been running. Â The results of this activity show that the activities have been running for one week does not always go smoothly. Â There are several obstacles such as some residents who could not attend due to personal matters and factors work So that this is the discussion in the evaluation activities led by the head of the household.
PENDAMPINGAN UMKM AL-MAIDAH CATERING JOGJA: SERTIFIKASI HALAL DAN PENGELOLAAN KEUANGAN
Authors: Manggala Putri Syah Amelia , Hayati Safaah Restuning , Sutrisno Sutrisno 
Published: March 2022

Perkembangan bisnis kuliner berbasis UMKM sangatlah pesat. Pemerintah mempunyai tanggunjawab terhadap keamanan dan kehalalan produk makanan di Indonesia. Sebagai negara dengan penduduk terbesar di dunia, masyarakat muslim Indonesia menjadikan aspek halal sebagai prioritas. Pemerintah berkontribusi dalam menjaga produk halal dengan sertifikasi halal yang dikeluarkan Lembaga Pengkajian Pangan Obat-Obatan dan Kosmetika Majelis Ulama Indonesia (LPPOM MUI). Sertifikat Halal mampu meningkatkan kepercayaan masyarakat yang berpengaruh positif terhadap penjualan. Sedangkan pengelolaan keuangan yang baik menjadikan UMKM akan lebih bersaing dan sejahtera. Permaslahan mitra timbul karena belum memiliki Sertifikat Halal dan belum memiliki pengelolaan keuangan yang memadai sehingga kurang optimal dalam melaksanakan ekspansi pasar. Tim pengusul mengajukan solusi atas permasalah tersebut dengan dilakukannya pelatihan dan pendampingan pengurusan Sertifikasi Halal dan pengelolaan keuangan. Hasil akhir dari kegiatan pengabdian kepada masyarakat ini yaitu berupa sertifikasi halal hasil dari pendampingan pengajuan sertifikasi halal kepada LPPOM MUI dan terlaksananya tata kelola keuangan usahaÂ dengan baikÂ oleh mitra pengabdian yang tercermin dari mitra pengadian telah mampu membuat pencatatan laporan keuangan sederhana serta menerapkan strategi pengelolaan keuangan dengan baik guna eksistensi keberlangsungan usaha.
Persepsi Petani Jagung Terhadap Program Upsus Pajale Pendukung Ketahanan Pangan di Kecamatan Bandar Sribhawono Kabupaten Lampung Timur
Authors: Nikmatullah Dewangga 
Published: March 2022

Tujuan penelitian adalah untuk mengetahui: (1) persepsi petani jagung terhadap Program Upsus Pajale, (2) faktor-faktor terkait dengan persepsi petani jagung terhadap Program Upsus Pajale. Penelitian menggunakan metode survei, pada bulan September–Desember 2017. Lokasi penelitian ditentukan secara sengaja (purposive). Jumlah petani sampel ditentukan dengan metode acak sederhana dan metode alokasi proporsional, sehingga diperoleh n = 142 petani (n1 = 44 petani dan n2 = 98 petani). Pengujian hipotesis menggunakan analisis uji statistika non-paramterik Korelasi Peringkat Spearman. Hasil penelitian bahwa : (1) persepsi petani terhadap Program Upsus Pajale termasuk dalam katagori baik. (2) faktor-faktor terkait dengan pesepsi petani jagung terhadap program Upsus Pajale adalah: (X1) pengetahuan petani, dan (X3) interaksi sosial petani jagung, sedangkan (X2) lama petani berusahatani jagung tidak mempunyai hubungan yang nyata.
Digital Flipbook as a Learning Media to Improve Visual Literacy for 4th Grade Students at SDN Abdi Negara
Authors: Hadiapurwa Angga , Listiana Annisa , Efendi Erika Erviana 
Published: March 2022

The current development of technology and information has an effect on the advancement of learning media innovation. One of them is the digital-based flipbook innovation. This research was conducted in an effort to utilize flipbook media in digital form to improve visual literacy of grade 4 elementary school students. The method used is quantitative method. Subjects in this study were students at SD Negeri 1 Abdi Negara. To obtain research data used a survey by filling out a questionnaire. Based on these data, it was found that students were easy to use digital flipbooks, easy to read the text, understood the material presented, felt interested and fun when using digital based flipbooks, and understood the material that was being tested. Based on the results of data analysis, it can be said that this digital-based flipbook can be used as a learning media.
Effect of serial in vivo passages on the adaptation of H1N1 avian influenza virus to pigs
Authors: Urbaniak Kinga , Kowalczyk Andrzej , Pomorska-Mól Małgorzata , Kwit Krzysztof , Markowska-Daniel Iwona 
Published: March 2022

Abstract

Introduction
The lack of proofreading activity of the viral polymerase and the segmented nature of the influenza A virus (IAV) genome are responsible for the genetic diversity of IAVs and for their ability to adapt to a new host. We tried to adapt avian IAV (avIAV) to the pig by serial passages in vivo and assessed the occurrence of point mutations and their influence on viral fitness in the pig’s body.

Material and Methods
A total of 25 in vivo avIAV passages of the A/duck/Bavaria/77 strain were performed by inoculation of 50 piglets, and after predetermined numbers of passages 20 uninoculated piglets were exposed to the virus through contact with inoculated animals. Clinical signs of swine influenza were assessed daily. Nasal swabs and lung tissue were used to detect IAV RNA by real-time RT-PCR and isolates from selected passages were sequenced.

Results
Apart from a rise in rectal temperature and a sporadic cough, no typical clinical signs were observed in infected pigs. The original strain required 20 passages to improve its replication ability noticeably. A total of 29 amino-acid substitutions were identified. Eighteen of them were detected in the first sequenced isolate, of which 16 were also in all other analysed strains. Additional mutations were detected with more passages. One substitution, threonine (T) 135 to serine (S) in neuraminidase (NA), was only detected in an IAV isolate from a contact-exposed piglet.

Conclusion
Passaging 25 times allowed us to obtain a partially swine-adapted IAV. The improvement in isolate replication ability was most likely related to S654 to glycine (G) substitution in the basic protein (PB) 1 as well as to aspartic acid (D) 701 to asparagine (N) and arginine (R) 477 to G in PB2, glutamic acid (E) 204 to D and G239E in haemagglutinin and T135S in NA.
Existence and multiplicity results for fractional p(x)-Laplacian Dirichlet problem
Authors: Chakrone O. , Belhadj K. , Sidi Ammi M. R. , Zerouali A. 
Published: March 2022

Abstract
In this paper, we study a class of fractional p(x)-Laplacian Dirichlet problems in a bounded domain with Lipschitz boundary. Using variational methods, we prove in different situations the existence and multiplicity of solutions.
PSYCHOLOGICAL WELL-BEING MAHASISWA YANG MENGIKUTI PEMBELAJARAN DARING PADA MASA PANDEMI COVID-19
Authors: Rahmawati Adinda Yusvika 
Published: March 2022

The purpose of this study is to describe the Psychological well-being of students participating in online learning during the COVID-19 pandemic. This research was conducted at the Islamic Psychology Study Program, IAIN Surakarta. This type of research is qualitative phenomenology. There are 3 informants selected by purposive sampling. Data collection techniques through structured interviews. Credibility of data using source triangulation. The data analysis technique used interpretative phenomenological analysis (IPA). There are three main themes found in the study, namely 1) Self-acceptance, 2) Perceived impact, 3) Expectations. The results of this study indicate that students have psychological well-being which is influenced by each dimension. The implications of this study are more interesting after the self-acceptance dimension is achieved, it is easier to achieve other dimensions, namely, life goals, environmental mastery, autonomy, positive relationships with others, and personal growth. Individuals who have gratitude will show positive emotions, gratitude has a relationship with happiness, so that the three informants have a mindset to continue to be grateful in whatever happens, therefore the informants are individuals who feel happiness. Keywords : Online learning, Psychological well-being, Gratitude
HEMORRHAGIC VASCULITIS (HENOCH-SCHONLEIN PURPURA) IN PREGNANCY: LITERATURE REVIEW AND CASE REPORT
Authors: Markin Leonid , Rachkevych Olena 
Published: March 2022

Aim. The paper aims at reviewing publications and analyzing a clinical case of Henoch-Schonlein purpura in a pregnant patient. This pathology is extremely rare in pregnancy (solely about 20 cases reported in the available literature)
Materials and Methods. A systematic literature search was performed in Pubmed and other sources on peculiarities of gestation in Henoch-Schonlein purpura. A case of Henoch-Schonlein purpura in a pregnant woman, who delivered in 2020 in Lviv Maternity Hospital №1 is presented.
Results and Discussion. Henoch-Shonlein purpura is extremely rare disease in pregnant women. Only about 20 cases are presented in all available literature. Pregnancy course in described cases was usually favorable. Most patients were delivered by cesarean section for different reasons. About 25% of presented cases were complicated by nephrotic syndrome and superposition of preeclampsia, requiring preterm delivery. No case of placental vasculitis was detected at histological examination of placentas. Our case report: 33-years old patient, primigravida. Henoch-Schonlein purpura diagnosed 8 years ago. The course of the disease was chronic recurrent with predominant skin and joints lesions. Nephrotic syndrome was observed 4 years before pregnancy for last time. The patient continuously received corticosteroid therapy. Course of pregnancy was complicated by mild preeclampsia in the third trimester. A healthy girl weighting 3200g was delivered physiologically at term. No complications were observed in the postpartum period.
Conclusions. Hemorrhagic vasculitis (Henoch-Shonlein purpura) is an extremely rare disease in pregnancy. In absence of nephrotic syndrome, the course of pregnancy and delivery is favorable, but these patients require\h thorough monitoring for early detection of nephrotic syndrome and/or preeclampsia manifestations.
MONITORING OF ADVERSE REACTIONS TO PENICILLINS IN PATIENTS OF HEALTHCARE INSTITUTIONS IN THE CITY OF KHARKIV AND KHARKIV REGION
Authors: Butko Yaroslava , Melenchenko Natalia , Tkachova Oksana , Kostyuchenko Tetyana 
Published: March 2022

Aim. The paper aims at analyzing the state of monitoring of adverse reactions to penicillins based on spontaneous reports of the pharmacovigilance system of Ukraine, received from healthcare institutions of Kharkiv region and the city of Kharkiv during 2017-2019.
Materials and Methods. The objects of the study included maps-reports of adverse reactions to the use of penicillins, which came from health care facilities of Kharkiv region and the city of Kharkiv to the pharmacovigilance system of Ukraine during 2017-2019. Information on adverse drug reactions was obtained using the method of collecting spontaneous messages in mixed form (paper and electronic versions).
Results. The analysis revealed that among the 6 INNs of the penicillin group, the largest number of adverse reactions were registered for amoxicillin / clavulanic acid (in 2017 - 73% of message cards, in 2018 - 54% of message cards, in 2019 - 70% of message cards). In the number of reports amoxicillin drugs ranked second place (in 2017 - 22% of card-messages, in 2018 - 43% of card-messages, in 2019 - 27% of card-messages).
Discussion. The recorded adverse reactions are not serious and most frequently manifested in the form of local reactions: itching, swelling and redness of the skin, as well as from the gastrointestinal tract: diarrhea and nausea. No serious adverse reactions with lethal outcome were reported.
Conclusions. The conducted monitoring confirmed the literature data on typical adverse reactions to antibiotics of the penicillin group. It has been established that penicillin-type antibiotics, namely amoxicillin/clavulanic acid and amoxicillin, have a high risk of adverse reactions as they are prescribed more frequently.
HISTORY OF DEVELOPMENT OF LAPAROSCOPIC AND ENDOSCOPIC SURGERY IN LVIV CLINICAL EMERGENCY CARE HOSPITAL
Authors: Matviychuk Bohdan , Hurayevskyy Artur , Stasyshyn Andrii , Korol Yaroslav 
Published: March 2022

Aim. The analysis of the history of minimally invasive surgery in a clinical emergency care hospital and the clinical cases associated with first robot-assisted operations.
Materials and Methods. We have analyzed 10180 inpatients' maps and protocols of surgical operations from 2002 to 2019. We have also studied the first minimally invasive interventions in the Clinic of Surgery and Endoscopy affiliated to the Faculty of Postgraduate Education of Danylo Halytsky Lviv National Medical University and the municipal non-profit institution "Lviv Clinical Emergency Care Hospital".
Results and Discussion. Until the early 1990s, the development of surgical technology took place mainly due to the talents of individual surgeons and their persistence in implementing new treatment methods. The directions of work of our Department of Endoscopic Surgery included the introduction of minimally invasive (laparoscopic) surgical interventions and endoscopic interventions using flexible endoscopy. Robot-assisted operation on a patient with diaphragmatic hernia using da Vinci surgical system was performed with three 8.5 mm robotic instruments and two 5 mm laparoscopic ones. The operation lasted for 6 hours. There were no intra- and postoperative complications. The patient was discharged home in satisfactory condition on the 3rd post-op day. Robot-assisted surgery for complicated gallstone disease was performed with three 8.5 mm robotic instruments and one 5 mm laparoscopic one. The operation lasted for 3 hours.
Conclusions.
1. The introduction of modern technologies and minimally invasive interventions results primarily from activities of the clinic's staff, the head of the structural unit and the hospital administration, as well as from the high professional level of surgeons.
2. The usage of minimally invasive, laparoscopic, endoscopic techniques, as well as that of da Vinci surgical system in clinical practice will improve therapeutic outcomes and quality of life among patients with surgical disorders.