bluuebunny/crossref_metadata_2025_split huggingface dataset:
Up-to-date evidence on image-guided thermal ablation for metastatic lung tumors: a review
Authors: Matsui Yusuke , Tomita Koji , Uka Mayu , Umakoshi Noriyuki , Kawabata Takahiro , Munetomo Kazuaki , Nagata Shoma , Iguchi Toshihiro , Hiraki Takao 
Published: July 2022

AbstractThe aim of this review was to summarize the latest evidence on image-guided thermal ablation therapies for lung metastases. PubMed was used to search for relevant articles that reported the oncological outcomes of thermal ablation for metastatic lung tumors, and those published in 2010 or later were selected for review. Ablative therapies were applied for lung metastases from various types of primary tumors, but most commonly colorectal ones. Radiofrequency ablation (RFA) was the most evaluated technique, followed by microwave ablation (MWA). The local control rates of ablative therapies were generally favorable, approximately 80–90% in many studies. Representative studies demonstrated promising overall survival rates of approximately 50% or higher 5 years after ablation for lung metastases from colorectal cancer or mixed types of primary tumors. Nevertheless, the survival outcomes varied depending on the type of primary tumor and background factors of patients such as other metastases and comorbidities. Several studies had aimed to compare the outcomes of various ablative therapies such as RFA, MWA, and cryoablation; however, conclusive data are not yet available to determine the most appropriate ablation modality for lung metastases. Further data accumulation is needed, especially for long-term outcomes and comparisons with other therapies.
Regionale Schizophrenie – Mediendiskurse zur Internationalisierung des Wiener Bankensektors. Eine Langzeitanalyse
Authors: Seethaler Josef , Musil Robert , Dietrich-Gsenger Marlene 
Published: July 2022

ZusammenfassungGroße Unternehmen und insbesondere Banken sind wichtige regionale Identitätsanker. Veränderungen bei den Eigentümern können nicht nur beträchtliche Auswirkungen auf Wirtschaftsstruktur und Beschäftigungsdynamik haben, sondern auch auf das Image und Selbstverständnis einer Region. In diesem Sinne geht der Beitrag den Fragen nach, wie aktive und passive Unternehmensübernahmen im regionalen Kontext – also Übernahmen im Ausland durch inländische Unternehmen und Übernahmen im Inland durch ausländische Unternehmen – in den Medien dargestellt, welche Ursachen und Folgen diskutiert und welche Argumente verwendet werden und ob sich die Darstellung unter sich wandelnden wirtschaftlichen Rahmenbedingungen im Laufe der Zeit verändert. Vermitteln die Medien alle Übernahmen nach ähnlichen Kriterien, die einer den Mainstream-Medien oft zugeschriebenen neoliberalen Grundhaltung entsprechen, oder folgen sie eher einer identitätsbildenden „Wir versus sie“-Dichotomie, die zu einer Ungleichbehandlung aktiver und passiver Übernahmen beiträgt? Die Ergebnisse einer Langzeitanalyse der Berichterstattung der Wiener Qualitätspresse über Übernahmen im regionalen Bankensektor zeigen eine deutliche „asymmetrische“ Darstellung aktiver und passiver Übernahmen, die wir „regionale Schizophrenie“ nennen: Die Implikationen für Wien, seinen Arbeitsmarkt, die Rentabilität lokaler Banken und seine Position als Bankenzentrum bilden für aktive und passive Übernahmen den bedeutungsvollsten Bezugspunkt. Methodisch zeigt das angewandte kombinierte quantitativ-qualitative Verfahren das Potenzial des Framing-Ansatzes für die Analyse der medialen Darstellung wirtschaftlicher Themen.
MetaMAP: a graphical tool for designing initiatives to support multiple sustainability goals
Authors: Maher Ray , Mann Samuel , McAlpine Clive A. 
Published: July 2022

AbstractThis paper presents MetaMAP: a new graphical tool and framework for designing well-integrated sustainability initiatives, and managing synergies and trade-offs regarding the Sustainable Development Goals (SDGs). The SDGs are highly interconnected, but many institutional structures and thinking paradigms lead us to look at them in isolation. This stifles innovation and social transformation. Most tools and frameworks, while valuable, focus on analysis, not design, and are limited to a particular discipline, sector, SDG, or geographic scale. Without holistic frameworks and collaborative tools, many sustainability practitioners may be playing chess without a board. To support a more integrated approach to achieve the SDGs, MetaMAP resembles architectural design tools which help users to synthesise knowledge, reframe complex situations, and identify stakeholders, leverage points, synergies, and trade-offs. MetaMAP applies a new meta-framework to organise concept maps developed collaboratively by interdisciplinary teams following a guided process. This framework integrates components of the natural environment, built environment, and society across multiple spatial and temporal scales. It incorporates concepts from social-ecological systems, planetary boundaries, design thinking, integral theory, ecosystem services, and ecological footprint, among others. MetaMAP was designed with input from over 170 people from diverse disciplines in five workshops, numerous case studies, and critique. This article demonstrates MetaMAP through its application to a case study in which a multidisciplinary team analysed the impacts of an Ecovillage across scales and designed synergetic initiatives. We then critique MetaMAP from four disciplinary perspectives. We envision that MetaMAP will support the design of sustainability initiatives which are more efficient, more broadly supported, and contribute to multiple SDGs simultaneously. By taking a systems view and applying design thinking, MetaMAP helps users to understand interlinkages, maximise synergies, and minimise trade-offs when designing specific SDG initiatives.
From Teleoperation to Autonomous Robot-assisted Microsurgery: A Survey
Authors: Zhang Dandan , Si Weiyong , Fan Wen , Guan Yuan , Yang Chenguang 
Published: July 2022

AbstractRobot-assisted microsurgery (RAMS) has many benefits compared to traditional microsurgery. Microsurgical platforms with advanced control strategies, high-quality micro-imaging modalities and micro-sensing systems are worth developing to further enhance the clinical outcomes of RAMS. Within only a few decades, microsurgical robotics has evolved into a rapidly developing research field with increasing attention all over the world. Despite the appreciated benefits, significant challenges remain to be solved. In this review paper, the emerging concepts and achievements of RAMS will be presented. We introduce the development tendency of RAMS from teleoperation to autonomous systems. We highlight the upcoming new research opportunities that require joint efforts from both clinicians and engineers to pursue further outcomes for RAMS in years to come.
Influence of XHV-adequate atmosphere on surface integrity
Authors: Prasanthan V. , Denkena B. , Bergmann B. 
Published: July 2022

AbstractIn aerospace engineering, high temperature alloys such as titanium are the preferred choice. However, machining of such materials remains a major challenge due to high process forces and process temperatures. Currently, machining is performed almost entirely in the presence of oxygen. This results in a process-inherent oxidation of the metal surface, which leads to higher tool wear during machining. By means of an oxygen-free machining undesirable oxidation reactions will be avoided and thus results in an extension of tool life. In addition, oxygen-free machining in an extreme high vacuum (XHV) adequate environment can influence the resulting workpiece surface and subsurface properties due to change in process forces and chip formation. In the present work, the influence of machining under air and XHV-adequate atmosphere is examined with regard to chip formation, workpiece surface topography and residual stresses. Significant differences can be seen in resulting surface integrity depending on the machining atmosphere.
Psychological complications in patients with acromegaly: relationships with sex, arthropathy, and quality of life
Authors: Cangiano Biagio , Giusti Emanuele , Premoli Caterina , Soranna Davide , Vitale Giovanni , Grottoli Silvia , Cambria Valeria , Mantovani Giovanna , Mungari Roberta , Maffei Pietro , Dassie Francesca , Giampietro Antonella , Chiloiro Sabrina , Tanda Maria Laura , Ippolito Silvia , Cannavò Salvatore , Ragonese Marta , Zambon Antonella , Persani Luca , Fatti Letizia Maria , Scacchi Massimo ,   on behalf of the “PRO-ACRO” study group on Motor Disability in Acromegaly, of the Italian Society of Endocrinology (SIE), Cavagnini Francesco , Ferone Diego , Corbetta Sabrina , Bartalena Luigi , Peccoz Paolo Beck , Arosio Maura , Lania Andrea , Colao Annamaria , Pivonello Rosario , Uberti Ettore Degli , Ghigo Ezio , Giustina Andrea , Martino Enio , Pontecorvi Alfredo , Sicolo Nicola , Trimarchi Francesco 
Published: July 2022

Abstract
Purpose
Current treatment of acromegaly restores a normal life expectancy in most cases. So, the study of persistent complications affecting patients’ quality of life (QoL) is of paramount importance, especially motor disability and depression. In a large cohort of acromegalic patients we aimed at establishing the prevalence of depression, to look for clinical and sociodemographic factors associated with it, and to investigate the respective roles (and interactions) of depression and arthropathy in influencing QoL.

Methods
One hundred and seventy-one acromegalic patients (95 women and 76 men, aged 20–85 years) among those recruited in a cross-sectional Italian multicentric study were investigated. Each patient filled in three validated questionnaires: AcroQoL, WOMAC (measuring articular pain, stiffness and functionality), and AIMS (evaluating articular symptoms and depression).

Results
A very high (up to 28%) depression rate was detected in acromegalic subjects. Two patients showing pathological AIMS depression scores, committed suicide during the three years observational period. In our population poor psychological status was significantly associated with female sex. Furthermore, a significant strong correlation was found between AIMS depression score and WOMAC score. Both depression and arthropathy-related motor disability turned out to independently contribute with similar strength to the impairment of QoL.

Conclusions
We report a high prevalence of depression in acromegaly, which is associated with female sex and arthropathy. Both depression and arthropathy strongly and independently contribute to the impaired QoL of patients. Our study shows that assessment and monitoring of psychological status is mandatory in acromegaly, also suggesting an inexpensive tool for this assessment.
Analysis of damage and fracture behavior in ductile metal sheets undergoing compression and shear preloading
Authors: Zistl Moritz , Brünig Michael , Gerke Steffen 
Published: July 2022

AbstractThe present paper comprises the experimental and numerical analysis of damage and fracture behavior of ductile metals under non-proportional loading with compression and shear preloading. For this purpose, biaxial experiments with the H-specimen using a pneumatic downholder for compression loading followed by failure under a tension stress state and corresponding numerical simulations are performed and analyzed. A thermodynamically consistent anisotropic continuum model is presented. It takes the effects of micromechanical damage mechanisms on the macro scale behavior as a motivation for a phenomenological description of damage behavior as a function of stress state. The experimental findings are compared with the results of tests with proportional load paths and corresponding numerical simulations. Thereto, strain fields of the critical areas of the specimens are analyzed by means of digital image correlation (DIC) technique. Compression and shear preloading can lead to significantly reduced ductility of the material with initiation of failure processes in the small damage strain range. Evolution of numerically predicted plastic and damage equivalent strains illustrates their stress state dependence. The numerical results are also confirmed by images of fracture surfaces taken by scanning electron microscopy (SEM). This experimental-numerical methodology is therefore an efficient tool to develop and validate general modeling approaches, and it is characterized by almost arbitrarily definable load paths with changes in stress states occurring in forming processes.
Relationship between landslides and long-term rainfall trends
Authors: Sato Tadamichi , Shuin Yasuhiro 
Published: July 2022

AbstractEvaluating how the changes in rainfall caused landslides is important to prevent sediment disasters. Using the soil water index (SWI) and a three-layer tank model, this study examined the relationship between the occurrence of landslides and long-term changes in rainfall in Miyagawa Village, Mie Prefecture, Japan, where shallow and deep-seated landslides have occurred at different times. The three-layer tank model detected the effects of long-term changes in rainfall on landslides. We educated that the change in the first storage tank layer indicates the potential risk of shallow landslides, while that in the second and third storage tanks indicates the potential risk of deep-seated landslides. Our method could be used to examine the effects of long-term changes in rainfall on landslides in the same region at different times, or over a wider area. Besides, these results are valid because the three-layer tank model used to calculate the SWI is applied throughout Japan, and its effectiveness has been verified.
An integrated local-search/set-partitioning refinement heuristic for the Capacitated Vehicle Routing Problem
Authors: Cavaliere Francesco , Bendotti Emilio , Fischetti Matteo 
Published: July 2022

AbstractIn this paper, an effective heuristic algorithm for large-scale instances of the Capacitated Vehicle Routing Problem is proposed. The technique consists in a local search method entangled with a restricted Set Partitioning problem optimization. Helsgaun’s LKH-3 algorithm has been used for the local search phase, with a number of implementation improvements. The restricted Set Partitioning formulation is solved by means of an exact commercial Integer Liner Programming solver. The resulting algorithm is able to consistently improve the solutions obtained by a state-of-the-art heuristic from the literature, as well as some of the best-know solutions maintained by the CVRPLIB website.
Addressing biohazards to food security in primary production
Authors: Djurle Annika , Young Beth , Berlin Anna , Vågsholm Ivar , Blomström Anne-Lie , Nygren Jim , Kvarnheden Anders 
Published: July 2022

AbstractThis review addresses ways to prepare for and to mitigate effects of biohazards on primary production of crops and livestock. These biohazards can be natural or intentional introductions of pathogens, and they can cause major economic damage to farmers, the agricultural industry, society, and international trade. Agroterrorism is the intentional introduction of animal or plant pathogens into agricultural production systems with the intention to cause socioeconomic harm and generate public fear. Although few acts of agroterrorism are reported, the threat of agroterrorism in Europe is real. New concerns about threats arise from the rapid advancements in biotechnology and emerging technologies. FORSA, an analytical framework for risk and vulnerability analysis, was used to review how to prepare for and mitigate the possible effects of natural or intentional biohazards in agricultural production. Analyzing the effects of a biohazard event involves multiple scientific disciplines. A comprehensive analysis of biohazards therefore requires a systems approach. The preparedness and ability to manage events are strengthened by bolstered farm biosecurity, increased monitoring and laboratory capacity, improved inter-agency communication and resource allocation. The focus of this review is on Europe, but the insights gained have worldwide applications. The analytical framework used here is compared to other frameworks. With climate change, Covid-19 and the war in Ukraine, the supply chains are challenged, and we foresee increasing food prices associated with social tensions. Our food supply chain becomes more fragile with more unknowns, thereby increasing the needs for risk and vulnerability analyses, of which FORSA is one example.
Immobilized CotA Laccase for Efficient Recovery of HEAVY OIL
Authors: Mahmoud Tahany , Liu Chunzhao , Samak Nadia A. 
Published: July 2022

AbstractCotA laccase was successfully expressed from Pichia pastoris. Magnetic reduced graphene oxide (MRGO) nanocomposite was synthesized and functionalized with iminodiacetic acid (IDA-NH2), and then chelated with Cu2+ for effective immobilization with His-tagged CotA laccase. The Cu2+-chelated MRGO (MRGO-IDA-Cu2+) showed 175 mg/g-support adsorption capacity. The immobilization of CotA laccase with MRGO-IDA-Cu2+ nano-hybrid composite was confirmed by Raman spectroscopy, Thermal Gravimetric Analysis, and X-ray diffraction. The use of nano-hybrid MRGO-IDA-Cu2+ composite to improve heavy oil recovery was investigated. The findings revealed that the interfacial tension between oil and water was reduced to ~ 90% of its original value, and the wettability was changed from the oil-wet state [θ = ∼ 115.2 − 124.5°] to the water-wet state [θ = ∼ 8.9 − 30.1°]. The increase of immobilized CotA laccase concentration and the ratio of nano-hybrid MRGO-IDA-Cu2+ composite decreases the value of interfacial tension (IFT) and contact angle (CA). The core-flooding studies revealed that the oil recovery process of 0.3 wt% nano-hybrid MRGO-IDA-Cu2+ composite was enhanced by 82.8%.
Graphical Abstract
Strategies for the Revalorization of Sewage Sludge in a Waste Water Treatment Plant Through the Integration of Hydrothermal Processing
Authors: Aragon-Briceño C. I. , Ross A. B. , Camargo-Valero M. A. 
Published: July 2022

AbstractDifferent strategies for sewage sludge management have been implemented to minimize the environmental impacts and benefit from the resources embedded in this waste stream. In that regard, Hydrothermal treatments (HTTs) of biomass can contribute generating high-value products (hydrochar) and enhancing biogas generation. In this work, different strategies were analysed for implementing HTTs at WWTPs considering the effect of 2 different process temperatures (160 and 250 °C) on different sewage sludge samples (primary, secondary and digestate sludge). Determination of carbon, nitrogen and phosphorus fate and mass and energy balances in hydrochar and process waters were carried out. HTT promoted solubilization of nitrogen, phosphorus and organic carbon up to 89%, 13% and 124% respectively. Moreover, biomethane yield increased up to 168% reaching methane concentrations up to 79% in the biogas. High heating values of hydrochars ranged from 12.0 to 18.2 MJ kg−1. The integration of HTT as an intermediate step between two-step anaerobic digestion process showed an increase in the net energy balance of up to 124% in comparison with the conventional anaerobic digestion process.
Graphical Abstract
Studies on the impact of road freight transport and alternative modes in Australia: a literature study
Authors: Peters L. J. B. , Chattopadhyay G. , Tuck M. A. 
Published: July 2022

AbstractThe freight sector in Australia has been growing at an ever-increasing rate due to domestic and international demand for goods, commodities, and resources. Increased volume of traffic comes with increased greenhouse gas. Greenhouse gas impacts climate change and air pollution, increasing the risk of public health and safety. The European Union used Marco Polo to shift transit freight from road to sea, rail, and inland waterways to reduce the number of trucks on the road to lessen congestion, less pollution, and more reliable and efficient transport of goods. Fuel Tax Credit was similarly introduced in Australia to address some of these issues. It is now time to analyse the impact of these schemes. This paper is a systematic literature review using the Mixed Method Appraisal Tool and Critical Appraisal Skills Programme. Findings include using alternative modes of transport for long distances reduces carbon dioxide and the likelihood of using renewable fuels like electric and hydrogen fuel for trucks. However, research was limited on renewable fuels.
Behaviour of CFST Stub Columns Subjected to Pure Compression
Authors: Horváth A. , Kollár D. , Kövesdi B. 
Published: July 2022

AbstractApplication of concrete-filled steel tubes (CFST) is becoming increasingly prominent in the civil engineering practice. However, the interaction of cross-sectional elements in CFST columns raises a number of questions, which have to be investigated in detail to improve design background and analytical resistance formulae. The aim of the current paper is to examine the structural behaviour of innovative concrete-filled steel tubes using different structural steel grades (S355, S500 and S960) and concrete classes (C30/37 and C60/75). Combination of normal or high strength steel with normal or high-performance concrete is a novel research topic of composite structures resulting in economic and optimal design for distinct civil engineering applications such as buildings, bridges, towers and masts, etc. An advanced finite element model is developed and validated based on previous experimental results found in the international literature in order to investigate the discrepancies in structural behaviour, load-bearing capacity and failure mode of stub columns subjected to pure compression. Validated numerical results are compared to formulae-based resistances and the applicability of standardised design methods are examined. In addition, a novel formula is proposed considering hardening of steel material in accordance with EN 1993-1-5. The developed formula can be used for the economic design of CFST stub columns, combining normal and high strength materials, where elastic shell buckling cannot occur (D/t ≤ 90ε2).
Follow-up after bariatric surgery: is it time to tailor it? Analysis of early predictive factors of 3-year weight loss predictors of unsuccess in bariatric patients
Authors: Voglino Costantino , Badalucco Simona , Tirone Andrea , Ciuoli Cristina , Cantara Silvia , Benenati Nicoletta , Bufano Annalisa , Formichi Caterina , Croce Federica , Gaggelli Ilaria , Vuolo Maria Laura , Vuolo Giuseppe 
Published: July 2022

AbstractBariatric surgery (BS) is the most effective treatment strategy for obesity. Nevertheless, a subset of patients does not reach a successful weight loss or experience long-term weight regain. Conflicting evidence exists regarding predictors of BS outcomes. We aimed to define the early factors linked to 3 year unsuccessful weight loss in order to promote a tailored close follow-up. We enrolled 443 patients who underwent BS from January 2014 to December 2018 with a 3 year follow-up. An unsuccessful BS outcome was defined as a percentage of total weight loss (%TWL) < 20. We compared the characteristics between successful and unsuccessful patients in order to identify predictor factors of unsuccess after surgery. We found that the proportion of patients with unsuccessful weight loss progressively increased from one to three years after BS. In a multiple regression model, only 1 month %TWL and sleeve gastrectomy (SG) were significantly associated with 3 year unsuccessful weight loss. We stratified our cohort in four groups according to the risk of BS unsuccess, in terms of 1 month %TWL and type of surgery (SG vs gastric bypass). Interestingly, groups showed a significant difference in terms of %TWL at each follow-up point. Patients submitted to SG with lower 1 month %TWL must be considered at higher risk of future weight regain; consequently, they require a tailored and closer follow-up.Graphical abstract