bluuebunny/crossref_metadata_2025_split huggingface dataset:
Subtransmission overhead lines mechanical monitoring for fast detection of damaging events
Authors: Quaia Stefano , Mauri Alessandro , Marega Matteo , Marchesin Alessio , Rampazzo Davide , Vergine Chiara 
Published: July 2022

AbstractDifferent harmful events affecting high voltage overhead lines (OHLs) cause changes in the mechanical tension (tensile strength) of conductors. A mechanical monitoring of OHLs, therefore, can provide useful additional information (compared with the information provided by the widely used SCADA systems) about the power system state. The tension measurements combined with a few environmental measurements (air temperature, wind speed) can be used for an automatic (fast) detection of different events and for their approximate location along an OHL, reducing the impact of these events. Referring to 132–150 kV sub-transmission OHLs, this paper proposes some original algorithms, based on the mechanical monitoring of OHLs, for the automatic detection of the following events: conductor breaking, fall of trees on the conductors, ice/snow sleeve accretion on the conductors, strands breaking and galloping. The proposed algorithms require a limited number of sensors placed along the OHLs for measurements of the conductor tension and weather-related quantities.
Peptoniphilus coli sp. nov. and Peptoniphilus urinae sp. nov., isolated from humans
Authors: Mbaye Babacar , Lo Cheikh Ibrahima , Dione Niokhor , Benabdelkader Sarah , Tidjani Alou Maryam , Brahimi Samy , Armstrong Nicholas , Alibar Stéphane , Raoult Didier , Moal Valérie , Million Matthieu , Fournier Pierre-Edouard , Fenollar Florence 
Published: July 2022

AbstractStrains Marseille-P3761 and Marseille-P3195 are representatives of two bacterial species isolated from human specimens. Strain Marseille-P3761 was isolated from the stool of a healthy volunteer, while strain Marseille-P3915 was cultivated from the urine of a kidney transplant recipient. Both strains are anaerobic Gram-positive coccoid bacteria. Both are catalase-negative and oxidase-negative and grow optimally at 37 °C in anaerobic conditions. They also metabolize carbohydrates, such as galactose, glucose, fructose, and glycerol. The major fatty acids were hexadecanoic acid for both strains. The highest digital DNA–DNA hybridization (dDDH) values of Marseille-P3761 and Marseille-P3195 strains when compared to their closest phylogenetic relatives were 52.3% and 56.4%, respectively. Strains Marseille-P3761 and Marseille-P3195 shared an OrthoANI value of 83.5% which was the highest value found with Peptoniphilus species studied here. The morphological, biochemical, phenotypic and genomic characteristics strongly support that these strains are new members of the Peptoniphilus genus. Thus, we suggest that Peptoniphilus coli sp. nov., and Peptoniphilus urinae sp. nov., are new species for which strains Marseille-P3761 (CSUR P3761 = CCUG 71,569) and Marseille-P3195 (CSUR P3195 = DSM 103,468) are their type strains, respectively of two new Peptoniphilus species, for which we propose the names Peptoniphilus coli sp. nov. and Peptoniphilus urinae sp. nov., respectively.
Rhodococcus pseudokoreensis sp. nov. isolated from the rhizosphere of young M26 apple rootstocks
Authors: Kämpfer Peter , Glaeser Stefanie P. , Blom Jochen , Wolf Jacqueline , Benning Sarah , Schloter Michael , Neumann-Schaal Meina 
Published: July 2022

AbstractThe Gram-positive strain R79T, isolated from the rhizosphere of young M26 apple rootstocks, was investigated by a polyphasic taxonomic approach. Phylogenetic identification based on the full-length 16S rRNA gene sequence revealed highest 16S rRNA gene sequence similarity to the type strains of Rhodococcus wratislaviensis (99.6%) and Rhodococcus opacus (99.2%) followed by Rhodococcus imtechensis (98.9%). All other 16S rRNA gene sequence similarities were below 98.65%. A phylogenomic tree calculated based on a whole-genome sequence also showed a distinct clustering with the type strain of Rhodococcus koreensis. Average nucleotide identity (ANI) values between whole-genome sequences of R79T and the closest related type strains were below 95% supported the novel species status. The DNA G + C content of R79T was 67.24% mol. Predominant fatty acids were C16:0, C15:0 and C17:1ω8c. The strain contained MK8-H2 as the major respiratory quinone. The polar lipid profile consists of diphosphatidylglycerol and phosphatidylethanolamine, as well as of some unidentified lipids. The peptidoglycan type of the strain is A1γ meso-diaminopimelic acid. Based on the obtained genotypic and phenotypic, including chemotaxonomic data, we conclude that R79T represents a novel species of the genus Rhodococcus, for which the name Rhodococcus pseudokoreensis sp. nov. is proposed. The type strain is R79T (= DSM 113102T = LMG 32444T = CCM 9183T).
Anaerococcus ihuae sp. nov. and Mediannikoviicoccus vaginalis gen. nov., sp. nov., two new bacteria isolated from human vaginal samples
Authors: Ly Claudia , Abou Chacra Linda , Birsal Eva , Haddad Gabriel , Lo Cheikh Ibrahima , Amstrong Nicholas , Alibar Stéphane , Courbière Blandine , Bretelle Florence , Fenollar Florence 
Published: July 2022

AbstractStrains Marseille-Q5893 (= CSUR Q5893 = CECT 30496) and Marseille-Q5883 (= CSUR Q5883 = CECT 30497) were isolated from vaginal samples using the culturomics approach. The 16S rRNA gene sequences of each strain were sequenced and then compared by BLASTn to the NCBI database. Strains Marseille-Q5893 and Marseille-Q5883 were most closely related to Anaerococcus obesiensis and Finegoldia magna, with identities of 98.5% and 90.0%, respectively. Strain Marseille-Q5893 is strictly anaerobic, while strain Marseille-Q5883 is facultative anaerobic. Both strains are Gram-positive, coccus-shaped, oxidase- and catalase-negative. The most abundant fatty acid for both strains is hexadecanoic acid, followed by 9-octadecenoic acid and tetradecanoic acid. Strain Marseille-Q5893 has a genome size of 1,831,271 bp with a G+C content of 29.4 mol%, whereas strain Marseille-Q5883 has a genome of 1,997,945 bp with a 33.6 mol% G+C content. The genomic comparison of closely related species with strains Marseille-Q5893 and Marseille-Q5883 showed that all digital DNA–DNA hybridization (dDDH) and orthologous average nucleotide identity (OrthoANI) values were lower than the published species thresholds (70% and 95–96%, respectively). Based on these data, we conclude that strain Marseille-Q5893 belongs to a new species in the family Peptoniphilaceae and strain Marseille-Q5883 belongs to a new genus in the family Peptostreptococcaceae. For these two new bacterial species, the names Anaerococcus ihuae sp. nov. and Mediannikoviicoccus vaginalis gen. nov., sp. nov., were proposed.
Tumor-Induced Osteomalacia: A Systematic Clinical Review of 895 Cases
Authors: Bosman Ariadne , Palermo Andrea , Vanderhulst Julien , De Beur Suzanne M. Jan , Fukumoto Seiji , Minisola Salvatore , Xia Weibo , Body Jean-Jacques , Zillikens M. Carola 
Published: July 2022

AbstractTumor-induced osteomalacia (TIO) is a rare and largely underdiagnosed paraneoplastic condition. Previous reviews often reported incomplete data on clinical aspects, diagnosis or prognosis. The aim of this study was to present a systematic clinical review of all published cases of TIO. A search was conducted in Pubmed, Embase, Web of Science from inception until April 23rd, 2020. We selected case reports and case series of patients diagnosed with TIO, with information on tumor localization and serum phosphate concentration. Two reviewers independently extracted data on biochemical and clinical characteristics including bone involvement, tumor localization and treatment. 468 articles with 895 unique TIO cases were included. Median age was 46 years (range 9 months–90 years) and 58.3% were males. Hypophosphatemia and inappropriately low or normal 1,25-dihydroxyvitamin D levels, characteristic for TIO, were present in 98% of cases. Median tumor size was 2.7 cm (range 0.5 to 25.0 cm). Serum fibroblast growth factor 23 was related to tumor size (r = 0.344,P < 0.001). In 32% of the cases the tumor was detected by physical examination. Data on bone phenotype confirmed skeletal involvement: 62% of cases with BMD data had a T-score of the lumbar spine ≤ − 2.5 (n = 61/99) and a fracture was reported in at least 39% of all cases (n = 346/895). Diagnostic delay was longer than 2 years in more than 80% of cases. 10% were reported to be malignant at histology. In conclusion, TIO is a debilitating disease characterized by a long diagnostic delay leading to metabolic disturbances and skeletal impairment. Increasing awareness of TIO should decrease its diagnostic delay and the clinical consequences.
Operational complexity and pumping lemmas
Authors: Dassow Jürgen , Jecker Ismaël 
Published: July 2022

AbstractThe well-known pumping lemma for regular languages states that, for any regular language L, there is a constant p (depending on L) such that the following holds: If $$w\in L$$

w
∈
L

and $$\vert w\vert \ge p$$

|
w
|
≥
p

, then there are words $$x\in V^{*}$$

x
∈

V

∗

, $$y\in V^+$$

y
∈

V
+

, and $$z\in V^{*}$$

z
∈

V

∗

such that $$w=xyz$$

w
=
x
y
z

and $$xy^tz\in L$$

x

y
t

z
∈
L

for $$t\ge 0$$

t
≥
0

. The minimal pumping constant $${{{\,\mathrm{mpc}\,}}(L)}$$

mpc

(
L
)

of L is the minimal number p for which the conditions of the pumping lemma are satisfied. We investigate the behaviour of $${{{\,\mathrm{mpc}\,}}}$$

mpc

with respect to operations, i. e., for an n-ary regularity preserving operation $$\circ $$
∘
, we study the set $${g_{\circ }^{{{\,\mathrm{mpc}\,}}}(k_1,k_2,\ldots ,k_n)}$$

g

∘

mpc

(

k
1

,

k
2

,
…
,

k
n

)

of all numbers k such that there are regular languages $$L_1,L_2,\ldots ,L_n$$

L
1

,

L
2

,
…
,

L
n

with $${{{\,\mathrm{mpc}\,}}(L_i)=k_i}$$

mpc

(

L
i

)

=

k
i

for $$1\le i\le n$$

1
≤
i
≤
n

and $${{{\,\mathrm{mpc}\,}}(\circ (L_1,L_2,\ldots ,L_n)=~k}$$

mpc

(
∘

(

L
1

,

L
2

,
…
,

L
n

)

=

k

. With respect to Kleene closure, complement, reversal, prefix and suffix-closure, circular shift, union, intersection, set-subtraction, symmetric difference,and concatenation, we determine $${g_{\circ }^{{{\,\mathrm{mpc}\,}}}(k_1,k_2,\ldots ,k_n)}$$

g

∘

mpc

(

k
1

,

k
2

,
…
,

k
n

)

completely. Furthermore, we give some results with respect to the minimal pumping length where, in addition, $$\vert xy\vert \le p$$

|
x
y
|
≤
p

has to hold.
Micro‐Hand Robot‐Assisted Versus da Vinci Robot‐Assisted Cholecystectomy: A Multi‐centre, Randomized Controlled Trial
Authors: Wang Guohui , Yi Bo , Li Zheng , Zhu Liyong , Hao Lin , Zeng Yijia , Zhu Shaihong 
Published: July 2022

AbstractObjectiveTo evaluate the clinical effectiveness of micro‐hand robot‐assisted cholecystectomy (MRC) by comparing the clinical outcomes of patients with benign gallbladder disease treated with micro‐hand or da Vinci robot‐assisted cholecystectomy (DRC).MethodsThis is a prospective, multi‐centre, single‐blind, and randomized controlled trial. In this study, 166 patients of benign gallbladder disease were randomized enrolled into two groups and received MRC or DRC (83 in the MRC group; 83 in the DRC group). The primary endpoint was surgical success rate. Secondary endpoints were the docking time, console time, total operation time, intraoperative blood loss, gallbladder breakage rate, postoperative pain, time of first flatus, the comprehensive complication index (CCI), and the hospital stay of the subjects. The duration of follow‐up was 30 days.ResultsNo conversion occurred. Compared with MRC, the DRC group showed longer docking time (12.04 min vs. 16.39 min, P = 0.025) and higher gallbladder breach rate (4.8% vs. 15.7%, P = 0.021). The MRC group showed higher postoperative pain scores compared to DRC (4.0 vs 3.0, P = 0.038). The console time, intraoperative blood loss, and gallbladder breach rate were comparable in these two groups (P > 0.05). No differences were observed in postoperative outcomes and complications between the two groups (P > 0.05).ConclusionsIn patients with benign gallbladder disease, the MRC showed no obvious clinical disadvantage compared with the da Vinci surgical robot. MRC is effective and safe and provides more options for surgical treatment.Trial Registration: This study was registered at ClinicalTrials.gov (NCT04122261). URL: https://clinicaltrials.gov/ct2/show/NCT04122261
Data-driven analysis and prediction of norm acceptance
Authors: Krestel Ralf , Kuhn Annegret , Hasselbring Wilhelm 
Published: July 2022

AbstractThat norms matter for politics is a widely shared observation. Existing political science research on norm diffusion, norm localization, and contestations is, however, constrained due to methodological manageability of empirical data. To face this research challenge, we propose an interdisciplinary research collaboration between political and computer science. Using the show case of energy politics, we want to conduct unsupervised and semi-supervised content analysis and fusion with the help of automated text mining methods to analyze the influence of different types of so-called norm entrepreneurs on the public acceptance and, respectively, contestations of different energy policies.
Short-term responses of Rana arvalis tadpoles to pH and predator stress: adaptive divergence in behavioural and physiological plasticity?
Authors: Scaramella Nicholas , Mausbach Jelena , Laurila Anssi , Stednitz Sarah , Räsänen Katja 
Published: July 2022

AbstractEnvironmental stress is a major driver of ecological and evolutionary processes in nature. To cope with stress, organisms can adjust through phenotypic plasticity and/or adapt through genetic change. Here, we compared short-term behavioural (activity) and physiological (corticosterone levels, CORT) responses ofRana arvalistadpoles from two divergent populations (acid origin, AOP, versus neutral origin, NOP) to acid and predator stress. Tadpoles were initially reared in benign conditions at pH 7 and then exposed to a combination of two pH (acid versus neutral) and two predator cue (predator cue versus no predator cue) treatments. We assessed behavioural activity within the first 15 min, and tissue CORT within 8 and 24 h of stress exposure. Both AOP and NOP tadpoles reduced their activity in acidic pH, but the response to the predator cue differed between the populations: AOP tadpoles increased whereas NOP tadpoles decreased their activity. The AOP and NOP tadpoles differed also in their CORT responses, with AOP being more responsive (CORT levels of NOP tadpoles did not differ statistically across treatments). After 8 h exposure, AOP tadpoles had elevated CORT levels in the acid-predator cue treatment and after 24 h exposure they had elevated CORT levels in all three stress treatments (relative to the benign neutral–no-cue treatment). These results suggest that adaptation to environmental acidification inR. arvalisis mediated, in part, via behavioural and hormonal plasticity.
Local inhomogeneous second-order characteristics for spatio-temporal point processes occurring on linear networks
Authors: D’Angelo Nicoletta , Adelfio Giada , Mateu Jorge 
Published: July 2022

AbstractPoint processes on linear networks are increasingly being considered to analyse events occurring on particular network-based structures. In this paper, we extend Local Indicators of Spatio-Temporal Association (LISTA) functions to the non-Euclidean space of linear networks, allowing to obtain information on how events relate to nearby events. In particular, we propose the local version of two inhomogeneous second-order statistics for spatio-temporal point processes on linear networks, the K- and the pair correlation functions. We put particular emphasis on the local K-functions, deriving come theoretical results which enable us to show that these LISTA functions are useful for diagnostics of models specified on networks, and can be helpful to assess the goodness-of-fit of different spatio-temporal models fitted to point patterns occurring on linear networks. Our methods do not rely on any particular model assumption on the data, and thus they can be applied for whatever is the underlying model of the process. We finally present a real data analysis of traffic accidents in Medellin (Colombia).
Large increases of multi-year droughts in north-western Europe in a warmer climate
Authors: van der Wiel Karin , Batelaan Thomas J. , Wanders Niko 
Published: July 2022

AbstractThree consecutive dry summers in western Europe (2018–2019–2020) had widespread negative impacts on society and ecosystems, and started societal debate on (changing) drought vulnerability and adaptation measures. We investigate the occurrence of multi-year droughts in the Rhine basin, with a focus on event probability in the present and in future warmer climates. Additionally, we investigate the temporally compounding physical drivers of multi-year drought events. A combination of multiple reanalysis datasets and multi-model large ensemble climate model simulations was used to provide a robust analysis of the statistics and physical processes of these rare events. We identify two types of multi-year drought events (consecutive meteorological summer droughts and long-duration hydrological droughts), and show that these occur on average about twice in a 30 year period in the present climate, though natural variability is large (zero to five events can occur in a single 30 year period). Projected decreases in summer precipitation and increases in atmospheric evaporative demand, lead to a doubling of event probability at 1 $$^\circ$$

∘

C additional global warming relative to present-day and an increase in the average length of events. Consecutive meteorological summer droughts are forced by two, seemingly independent, summers of lower than normal precipitation and higher than normal evaporative demand. The soil moisture response to this temporally compound meteorological forcing has a clear multi-year imprint, resulting in a relatively larger reduction of soil moisture content in the second year of drought, and potentially more severe drought impacts. Long-duration hydrological droughts start with a severe summer drought followed by lingering meteorologically dry conditions. This limits and slows down the hydrological recovery of soil moisture content, leading to long-lasting drought conditions. This initial exploration provides avenues for further investigation of multi-year drought hazard and vulnerability in the region, which is advised given the projected trends and vulnerability of society and ecosystems.
Future extension of the UK summer and its impact on autumn precipitation
Authors: Cotterill Daniel F. , Pope James O. , Stott Peter A. 
Published: July 2022

AbstractResearch into weather circulation changes over the UK for future climate has mainly focused on changes in the Summer and Winter seasons, with less analysis on seasonality and the transition seasons. Using the 30 Met Office weather patterns we examine the influence of climate change on seasonality through atmospheric circulation using a number of climate models. Changes in seasonality are important as they can have large impacts on many sectors including agriculture, energy and tourism. This paper finds a noticeable increase in Autumn over the UK in the frequency of drier summer-type regimes and a decrease in stormy winter types that emerge as early as the 2020s. The change in circulation signal once isolated from the overall signal is responsible for a 4–12% decrease in Autumn mean rainfall on average for England by the end of this century (where the values in the range are dependent on the emissions scenario). This change is projected over English regions that are already experiencing water stress, and with predictions of drier summers over the UK in future, this could further increase drought risk. The change in circulation in Autumn also moderates the large increase in the number of large-scale extreme daily rainfall events over the same regions predicted due to climate change. While this future circulation change is replicated across all the climate models used, large differences remain in the strength of the signal between models. The climate models used replicate the frequency of the 30 weather patterns well for all seasons.
Oral intake of xanthohumol attenuates lipoteichoic acid-induced inflammatory response in human PBMCs
Authors: Jung Finn , Staltner Raphaela , Tahir Ammar , Baumann Anja , Burger Katharina , Halilbasic Emina , Hellerbrand Claus , Bergheim Ina 
Published: July 2022

AbstractPurposeThe aim of the study was to determine if xanthohumol, a prenylated chalcone found in Hop (Humulus lupulus), has anti-inflammatory effects in healthy humans if applied in low doses achievable through dietary intake.MethodsIn a placebo-controlled single-blinded cross-over design study, 14 healthy young men and women either consumed a beverage containing 0.125 mg xanthohumol or a placebo. Peripheral blood mononuclear cells (PBMCs) were isolated before and 1 h after the intake of the beverages. Subsequently, PBMCs were stimulated with or without lipoteichoic acid (LTA) for 24 and 48 h. Concentrations of interleukin-1β (IL-1β), interleukin-6 (IL-6) and soluble cluster of differentiation (sCD14) protein were determined in cell culture supernatant. Furthermore, hTLR2 transfected HEK293 cells were stimulated with LTA in the presence or absence of xanthohumol and sCD14.ResultsThe stimulation of PBMCs with LTA for 24 and 48 h resulted in a significant induction of IL-1β, IL-6, and sCD14 protein release in PBMCs of both, fasted subjects and subjects after the ingestion of the placebo. In contrast, after ingesting xanthohumol, LTA-dependent induction of IL-1β, IL-6, and sCD14 protein release from PBMCs was not significantly higher than in unstimulated cells after 48 h. In hTLR2 transfected HEK293 cells xanthohumol significantly suppressed the LTA-dependent activation of cells, an effect attenuated when cells were co-incubated with sCD14.ConclusionThe results of our study suggest that an ingestion of low doses of xanthohumol can suppress the LTA-dependent stimulation of PBMCs through mechanisms involving the interaction of CD14 with TLR2. Study registered at ClinicalTrials.gov (NCT04847193, 22.03.2022).