bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is Testosterone the “Fountain of Youth” for Aging Men?
Authors: Giagulli Vito Angelo , Lisco Giuseppe , Mariano Francesco , De Tullio Anna , Triggiani Vincenzo 
Published: May 2022

Background:
Late-Onset Hypogonadism (LOH) is defined as a clinical and biochemical
syndrome associated with advancing age. It is characterized by specific symptoms and less
specific manifestations due to deficiency of serum testosterone (T) levels.

Objective:
This review aims to summarize the evidence related to LOH definition, diagnostic
approach, and treatment to answer a clinical question: “Is Testosterone the fountain of youth for
aging men?".

Methodology:
MEDLINE/PubMed and institutional websites were searched for original papers,
guidelines, and position statements published in the last ten years.

Results:
Observational and randomized controlled studies on T replacement therapy in older men
have been reported.

Discussion and Conclusion:
Despite some heterogeneities regarding diagnostic definition, therapeutic
target, and testosterone prescription, all guidelines agreed that male hypogonadism should
be diagnosed and managed in aged men as in adulthood. However, trials assessing the efficacy
of T therapy conducted for male rejuvenating are lacking; thus, T prescription for this purpose is
not recommended.
A New Device for Remote Monitoring of Vital Parameters in Acromegalic
Patients: Pilot Study
Authors: Costa Denise , D’Amico Tania , Mercuri Valeria , Schiaffini Riccardo , Gargiulo Patrizia 
Published: May 2022

Introduction:
Acromegaly is a rare disease that results from growth hormone (GH)
excess. Diabetes mellitus, hypertension,cardiomyopathy, and obstructive sleep apnoea syndrome(
OSAS) are frequent complications.

Aim of the study:
Identify a useful system to obtain a reliable remote monitoring of glucose and
the most important vital parameters in the acromegalic subjects.

Patients and Methods:
Sixteen acromegalic patients (from 30 to 73 years old) were enrolled. We
provided health monitor devices to the patients for continuous acquisition of physiological signals
including twelve-lead electrocardiography (EKG) and nocturnal SpO2. At the same time, we applied
on the same patients the blinded continuous glucose monitoring system(CGMS).

Results:
The lowest saturation peaks at night (<80%) were achieved in patients with a known
diagnosis of OSAS. A positive correlation was demonstrated between the lowest oxygen saturation
values and the CGM peaks (pV <0,0001) and between the average values of oxygen saturation
and CGM (pV<0,0003). Patients with a previous diagnosis of OSAS, obtained by polysomnography,
showed on the multiparametric monitor recordings superimposable to their known
condition. Instead we noticed a discordance in the two EKG recording: the wireless mode showed
an irregular rhythm in 5/16 patients, which was not confirmed by the recording mode with cables.

Conclusion:
The health monitor device associated with CGM may be a new useful and versatile
tool for fragile patients who can self-manage remote monitoring, and for physicians who can
obtain real-time information for the clinical and therapeutic management of patients. It is also a
useful tool for the follow-up of patients with OSAS. Moreover, once the interference of the OSAS
is excluded, the CGM allows us to obtain a more reliable and accurate diagnosis of DM.
A Chronic Inflammatory Inductive Condition in the Nursing Profession: A
Scoping Review
Authors: Vitale Elsa 
Published: May 2022

Background:
Literature focuses on the well-being of patients and little on the well-being of nurses who, in turn, should be educated about well-being. The latter, on the other hand, very often have to work under serious pressure with inadequate resources and shift organization exposing them to health risk factors.

Objective:
To highlight which relationships exist between: diet, physical activity, body mass index (BMI) and mental health in the nursing profession.

Methods:
Author searched Medline (PubMed) database for medical subheadings terms and free full text referred to “Diet”, “Mental Health”, “Physical Activity”, “Nurses”, before 31st December 2020.

Results:
A total of 11 studies were included in this perspective review which better defined the relationships existing between diet, physical activity, mental health and nursing profession.

Conclusion:
From the studies present in literature it emerges that the nursing profession has an inherent imbalance in the regular circadian activity of human nature, as nursing assistance is provided 24 hours a day, therefore also during the night. Numerous studies have already highlighted significant differences between levels of mental and eating disorders among nurses who also work at night versus those who only work during the day. Therefore, it is possible to speak of the nursing profession as an “inductive inflammatory-chronic” activity on the basis of the extensive scientific evidence provided by literature.
Impact of a Papillomavirus Vaccination Promotion Program in Middle School: Study Protocol for a Cluster Controlled Trial
Authors: Tran Phuong Lien , Chirpaz Emmanuel , Boukerrou Malik , Bertolotti Antoine 
Published: May 2022

Background
On Reunion Island, incidence and mortality for uterine cervical cancer is high, yet coverage rate for human papillomavirus (HPV) vaccination is low.

Objective
The main objective of the study is to evaluate the impact of a health promotion program promoting HPV vaccination on the proportion of middle school girls who complete the full HPV vaccination schedule (2 or 3 doses) by the end of school year.

Methods
This study is a cluster controlled intervention study using a superiority design. A combined health promotion program will be offered containing information to students and parents, training of general practitioners, and free school-based vaccination (in a “health bus”). Children who attend this program will constitute the intervention group and will be compared to children from another middle school who will not attend the program constituting the control group.

Results
Recruitment began in October 2020. In the intervention school, of 780 students, 245 were randomly selected in the 12 classes. In the control school, 259 students out of 834 were randomly selected.

Conclusions
In this study, we explore the impact of a health promotion program combining information toward students, parents, and general practitioners with free school-based vaccination. We expect a significantly higher HPV vaccination coverage in the intervention school as compared to the control school, whether it be among girls or boys. The final implication would be an extension of this program in all middle schools on the Island and thus an increase in HPV vaccination coverage.

Trial Registration
ClinicalTrials.gov NCT04459221; https://clinicaltrials.gov/ct2/show/NCT04459221

International Registered Report Identifier (IRRID)
DERR1-10.2196/35695
The First National Remote Emergency System for Malignant Hyperthermia (MH-NRES) in China: Protocol for the Design, Development, and Evaluation of a WeChat Applet
Authors: Yu Hong , Tan Lingcan , Teng Yi , Xu Zhao , Xiao Kun , Yin Jin , Zuo Yunxia , Zhu Tao , Deng Xiaoqian 
Published: May 2022

Background
Malignant hyperthermia (MH) is a rare life-threatening anesthetic emergency. With respect to the high fatality rate, difficulty in early recognition, and the lack of disease-specific drug (ie, dantrolene) in China, more effort is needed to strengthen early diagnosis and effective treatment of MH emergencies. Nowadays, mobile health (mHealth) apps are changing the way of medical practice; they can serve as an accessible tool to help anesthesiologists deal with MH crises. However, no related mHealth-based emergency system is available currently.

Objective
The aim of this study is to outline the protocol for the development of a WeChat applet used to design a National Remote Emergency System for Malignant Hyperthermia (MH-NRES) in China, as well as the protocol for the evaluation of the user experience and perception of the system.

Methods
The system adopts the client-server architecture, with a custom user interface operating as clients and the back-end system operating as the server. The client-side software was developed using uni-app technology with Vue.js-based framework, which consists of 6 modules: Quick Diagnosis, Dantrolene Mobilization, Instruction on Dantrolene Use, MH Treatment, Recovery Period Treatment, and DNA Test and Biopsy. The back-end system was developed based on the Spring framework. The system will be evaluated by administrating a modified user version of the Mobile App Rating Scale. Pilot testing will be conducted in Sichuan Province, China, and a subsequent evaluation on a national scale is planned.

Results
The theoretical framework design of this system was completed in August 2021. The development of the system was completed in February 2022, and the refinement is currently ongoing. Pilot testing after the implementation of the system in Sichuan Province is planned to take 2 months, and the subsequent evaluation on a national scale is planned to take 2 months.

Conclusions
We have described a novel approach using the WeChat applet to develop the MH-NRES. Findings from the usability testing process in the current study may lead to refinements and is expected to suggest that this system is both feasible and welcomed by anesthesiologists. Depending on the availability of research funding, this system will be extended nationally across China.

International Registered Report Identifier (IRRID)
PRR1-10.2196/37084
De la geopolítica y la política en tiempos de caos sistémico: una mirada desde América Latina/Abya Yala
Authors: Licio Caetano do Rego Monteiro Licio , Porto-Gonçalves Carlos Walter 
Published: May 2022

<span lang="es-419">El propósito de este artículo es comenzar una discusión sobre el papel de Abya Yala. </span>América Latina en el escenario geopolítico contemporáneo. Con este fin, busca volver a l formación histórica y territorial del continente en sus momentos clave, demostrando la relevancia de la conquista colonial del continente americano para la proyección geopolítica europea en su relación con Asia (siglos XV-XIX) y el peso de esta larga duración al observar la ascensión china y sus repercusiones continentales y globales actuales. Creemos que una mirada geopolítica tradicional, a gran escala y centrada en las grandes potencias económicas y en los estados, debe enfrentarse a otros puntos de vista y escalas que buscan reconocer el papel activo de los grupos / clases sociales en las diferentes relaciones sociales y de poder que marcan y sus escalas, que redefinen los eventos de la geopolítica global. El articulo está dividido en tres partes, a saber, (1) un análisis de la constitución del sistema mundo y de la importancia de la América para comprehender ese sistema, (2) una reinterpretación de la colonialidad que ha sobrevivido al término del colonialismo e (3) a emergencia política de la América /Abya Yala Profunda.
Landscapes of Postmodernity: Donald Barthelme's Architecture
Authors: Sierra Nicole 
Published: May 2022

ABSTRACT
Exploring Donald Barthelme's literary representations of architecture, this essay traces how the author manipulates architectural history as a means of critiquing modernism and contemporary culture. Despite frequent references to Barthelme's familial relationship to architecture, little has been studied about how this intimacy is encoded in his imaginative writings. Focusing on the short story collections Sixty Stories and Forty Stories, this essay considers the usefulness of architecture as an interart analogy for Barthelme's texts. Seizing on the theories of Fredric Jameson, I argue that Barthelme's works highlight popular displeasure with modernist orthodoxy by using strategies similar to early postmodern architecture.
Model Pembelajaran Kooperatif Tipe Think Pair Share (TPS) Untuk Meningkatkan Hasil Belajar IPA Siswa SMP
Authors: Sukadana I Nyoman 
Published: May 2022

Rendahnya pencapaian nilai ketuntasan siswa tersebut diduga disebabkan beberapa hal, yaitu kurangnya minat belajar siswa, terutama minat untuk membaca materi, kurangnya motivasi belajar siswa, metode pembelajaran yang digunakan oleh guru kurang memotivasi siswa untuk terlibat secara aktif dalam proses pembelajaran. Penelitian ini bertujuan untuk menganalisis model pembelajaran kooperatif tipe Think Pair Share (TPS) untuk meningkatkan hasil belajar IPA siswa SMP. Jenis penelitian ini merupakan penelitian tindakan kelas dengan subjek penelitian ini adalah siswa kelas VIII SMP yang berjumlah 40 orang. Penelitian tindakan kelas ini dilaksanakan dalam dua siklus. Setiap siklus terdiri dari tahap perencanaan, pelaksanaan tindakan, observasi/evaluasi, dan refleksi. hasil belajar siswa dikumpulkan dengan tes dalam bentuk soal objektif. Teknik analisis secara deskriptif kualitatif. Hasil analisis data penelitian ini, pada siklus I rata-rata hasil belajar adalah 72 dengan ketuntasan adalah 72%; dengan kualifikasi belum tuntas. Pada siklus II rata-rata hasil belajar adalah 82 dengan ketuntasan klasikal adalah 97% dengan kualifikasi tuntas. Maka, penerapan model pembelajaran Think Pair Share (TPS) dapat meningkatkan hasil belajar siswa kelas VIII di SMP. Implikasi penelitian ini diharapkan dapat meningkatkan hasil belajar siswa dengan meningkatkan kinerja siswa dalam tugas-tugas akademiknya.
Penggunaan Video Pembelajaran untuk Meningkatkan Kemampuan Pemecahan Masalah Fisika
Authors: Sitinjak Erni Kusrini 
Published: May 2022

Kegiatan pembelajaran daring mahasiswa mengalami kesulitan dalam menyelesaikan soal–soal perhitungan fisika yang kompleks. Mahasiswa tidak memahami konsep sehingga kesulitan dalam memecahkan masalah fisika. Kesulitan yang dialami mahasiswa disebabkan oleh media pembelajaran yang digunakan oleh dosen cenderung biasa dan tidak interaktif. Penelitian ini bertujuan untuk menganaisis efektifitas penggunaan video pembelajaran untuk meningkatkan kemampuan pemecahan masalah fisika. Jenis penelitian yang digunakan adalah penelitian eksperimen dengan rancangan one group pre test – post test design. Sampel penelitian ini adalah mahasiswa pendidikan matematika yang mengikuti mata kuliah Fisika berjumlah 50 orang sebagai kelas eksperimen. Teknik pengumpulan data dalam penelitian ini adalah teknik tes dan non tes. Teknik analisis data menggunakan analisis kuantitatif dengan menggunakan persamaan N-Gain. Hasil penelitian menunjukkan nilai signifikansi (2-tailed) sebesar .000 < 0.005 artinya bahwa Ha diterima. Karena Ho ditolak dan Ha diterima artinya bahwa terdapat hasil yang signifikan dari penggunaan video pembelajaran terhadap kemampuan pemecahan masalah fisik. Sehingga penggunaan video pembelajaran efektif untuk meningkatkan kemampuan pemecahan masalah fisika mahasiswa. Implikasi penelitian ini diharapkan dapat meningkatkan kemampuan pemecahan masalah mahasiswa selama proses pembelajar.
Pengembangan Aplikasi Line Sebagai Manajemen Perkuliahan Mahasiswa Sistem Informasi
Authors: Pratami Della Shandia , Ribuna Meilani Sri , Maharani Gabriella Natasha , Primasari Clara Hetty 
Published: May 2022

Pada era globalisasi ini teknologi berkembang sangat pesat dan semakin canggih, ada banyak penggunaan media baru yg bermunculan. Salah satunya adalah LINE. LINE termasuk jejaring sosial yang sering digunakan oleh banyak mahasiswa. Selama masa pandemi yang diakibatkan oleh COVID-19 ini, proses belajar mengajar dilakukan secara daring. banyaknya aplikasi pembelajaran yang sudah digunakan, bahkan aplikasi chatting pun digunakan untuk belajar. Penelitian ini kami lakukan untuk membuat sistem yang dapat digunakan untuk mengakses website perkuliahan dalam aplikasi LINE, sehingga dapat mempermudah mahasiswa, dosen, maupun pengelola sistem website kampus UAJY. Metode penelitian yang diterapkan pada penelitian ini yaitu Waterfall yang merupakan sebuah metode pengembangan sistem informasi yang sekuensial dan sistematik.
Kata kunci: Sistem, Perkuliahan, Penggunaan Sosial Media Untuk Proses Belajar, Waterfall

Abstract. In this era of globalization, technology is developing very rapidly and increasingly sophisticated, there are many uses of new media that have emerged. One of them is Line. Line is a social network that is often used by many students. During this pandemic caused by COVID-19, the teaching and learning process is carried out online. many learning applications that have been used, even chat applications are used for learning. We did this research to create a system that can be used to access the lecture website in the LINE application, so that it can make it easier for students, lecturers, and managers of the UAJY campus website system. The research method applied in this research is Waterfall which is a sequential and systematic method of developing information systems.
Keywords: Sistem, Perkuliahan, Penggunaan Sosial Media Untuk Proses Belajar,Waterfall
Physico-Mechanical Properties of Thermoplastic Composite Reinforced with Kelempayan, Oil Palm Trunk and Bamboo as Fillers
Authors: Mahmud Siti Zalifah 
Published: May 2022

Thermoplastic composite panel can be used for a variety of applications. The wide distribution, renewability and recyclability of lignocelluloses can expand the market for low-cost thermoplastic composites. Lignocellulosic materials from fast growing and plantation species such as lesser-known timber, bamboo and palm tree are promising materials for particulate filler for the production of thermoplastic composite panel due to its accessibility, great substrate behaviour and high yield resources. This study was to determine the physico-mechanical properties of thermoplastic composite panel reinforced with particulate fillers from kelempayan (Neolamarckia cadamba), oil palm (Elaeis guineensis) and betong bamboo (Dendrocalamus asper). This study focused on the effect of particle size and three percent additive to dimensional stability and strength properties of a panel. The polypropylene plastic has been blended with the particulate fillers in a dispersion mixture at the temperature of 180 °C. Then, it was hot pressed for five to nine minutes and the mold was cold pressed for three minutes before the panel was conditioned for testing performance. Statistical analysis has proven that different particle sizes and the supplementary of three percent additive significantly influenced the physico-mechanical properties of the thermoplastic composite panel.
Physicochemical properties and sensory acceptability of different varieties of coconut water and flesh
Authors: Ab Mutalib Siti Roha , Jailani Fadhilah 
Published: May 2022

Coconut water is a sweet and refreshing drink obtained directly from the immature coconut and its flesh is smooth with a jelly-like structure. This study was carried out to evaluate the physicochemical properties and sensory acceptability of different varieties of coconut water and flesh. , The varieties of coconut used in this study were tall, dwarf, and hybrid coconut. Firstly, the weight of the coconuts were determined in which the tall variety was the heaviest coconut compared to the others. Tall coconut also showed a significantly higher amount of water volume and weight of coconut flesh. The dwarf coconut water revealed the highest pH (5.48± 0.02) with the lower titratable acidity (0.045±0.01 %). The highest total soluble solid (4.97±0.15 oBrix) was found in tall coconut. The fructose and glucose content of coconut water were found in a range of 2.70-3.58% and 2.04-3.24%, respectively. Potassium was the most abundant mineral in all coconut samples in which a larger quantity was found in water of tall coconut and flesh of dwarf coconut. The Folin–Ciocalteu method showed that dwarf coconut water (9.07±0.00 mg GAE/100 ml) and hybrid coconut flesh (11.57±0.34 mg GAE/100 g) had higher phenolic content than the others. Hybrid coconut flesh exhibited the lowest crude fat content (18.33±1.22 %) than others. Meanwhile, dwarf and hybrid coconut water were more acceptable and appreciated in terms of taste, sweetness, sourness, and overall acceptability. Although the tall coconut flesh was the least acceptable in terms of taste and texture, all samples' overall acceptability was acceptable. In conclusion, dwarf and hybrid coconut have a big potential to produce high-quality beverages and have a good quality of flesh.
Una lectura de <em>Memorias de abajo</em>
Authors: Díaz Márquez Ilse 
Published: May 2022

Leonora Carrington, una de las mayores expositoras del surrealismo, vivió angustiados años debido a su desequilibro mental y al contexto de la Segunda Guerra Mundial. En Memorias de abajo reconstruye el manicomio donde fue sometida a tratos inhumanos tras separarse de Max Ernst y abandonar Francia. El estado mental de Carrington la lleva a estructurar el lugar nombrado Abajo como "el pabellón para los enfermos en curación, la antesala de la libertad" (a decir de la autora Díaz Márquez), contrario a Villa Covadonga, donde los pacientes sufrían tortura física y psicológica. Sin duda estos episodios marcarían su obra pictórica y literaria posterior.
El presidencialismo mexicano
Authors: Bravo Gutiérrez Emmanuel 
Published: May 2022

La historia del presidencialismo en México se ve ligada a la historia de la corrupción y avaricia de sus servidores públicos. En este recorrido, diversos ilustradores muestran, con dejos caricaturescos, irónicos y humorísticos, los rasgos tanto personales como diplomáticos de los mandatarios que han estado al frente del país. Desde los presidentes que más años han perdurado en su cargo hasta aquellos que lo han hecho por sólo un par de días, este paseo da cuenta de que incluso una responsabilidad tan grande puede resultar a su vez, conflictos de intereses de por medio, sumamente endeble.
Observatorio de Políticas Culturales
Authors: Becerra-Zavala María de Lourdes 
Published: May 2022

Los Observatorios de Políticas Culturales son una figura que aparece a finales del siglo XX en Europa. Si bien no existe una sola definición de estos observatorios, pueden identificarse aspectos comunes como el acopio y análisis de información para la investigación y/o la toma de decisiones en el diseño de políticas culturales. El Observatorio de Políticas Culturales de la Facultad de Antropología (OPC-FAUV) inició en 2010, y dentro de las metas alcanzadas están un sistema de indicadores, una página web en la cual se puede acceder al sistema de información construido, y un boletín de divulgación. Las perspectivas del OPC-FAUV se orientan al monitoreo y análisis de los indicadores propuestos, para favorecer las condiciones de ejercicio de los derechos culturales de las comunidades en las que la FAUV realiza actividades de gestión cultural.Abstract: Observatories of Cultural Policies are a figure that appears in the late twentieth century Europe. While there is no single definition of these observatories, commonalities can be identified as the collection and analysis of data for research and / or decision-making in designing cultural policies. The Observatory of Cultural Policies of the Facultad de Antropología (OPC-FAUV) began in 2010. The major goals achieved are an indicator system, a web page where access the information system built, and a newsletter. Prospects OPC FAUV are aimed at monitoring and analysis of the proposed indicators, to promote the conditions for exercise of cultural rights of communities in which the FAUV has been realized cultural agency.