bluuebunny/crossref_metadata_2025_split huggingface dataset:
Terapia cognitivo-conductual en el trastorno del deseo sexual hipoactivo
Authors: Lema Chauca Jessica Alejandra , Hernández Rodríguez Yenima de la Caridad 
Published: April 2022

El objetivo es ejecutar una revisión de estudios en idioma español en cuanto al tratamiento cognitivo conductual para el Trastorno del Deseo Sexual Hipoactivo (TDSH). Se consultaron bases de datos como Scopus, Elsevier, Dialnet, Medline, PubMed, entre otras. Se encontraron en un total de 60 estudios. De aquellos se preseleccionaron 41. Finalmente se tomó una selección de 28 estudios. En los hallazgos se observa que un 50% de los estudios refieren la aplicación y efectiva de la terapia cognitiva conductual a corto y largo plazo en el trastorno mencionado con anterioridad, un 39% menciona al aspecto farmacológico, 7% al modelo Master & Johnson, 3% a la terapia sexual modelo Trudel. Otros aspectos importantes consisten en que el 42% pertenecen a España, el 62% pertenece a estudios de años 2013 hasta el 2020. La investigación realizada demostró que la terapia cognitivoconductual tienen eficacia para tratar la TDSH tanto en tratamientos individuales como en pareja, pues la principal etiología que se recoge es la Psicología, de acuerdo con la información proporcionada en los estudios, a pesar de que en varios casos se presenta un tratamiento farmacológicocomo una opción de solución rápida.
Layanan hotline konsultasi masalah kesehatan pasca Covid-19
Authors: Ermayanti Sabrina , Russilawati Russilawati , Anggraini Fenty , Afriani Afriani , Madison Irvan , Khairsyaf Oea , Basyar Masrul , Herman Deddy , Sabri Yessy Susanty , Fitrina Dewi Wahyu , Mirzati Dessy , Sari Elsa Purnama , Firdaus Dimas Bayu 
Published: April 2022

Pandemy of Corona virus disease 2019 (Covid-19) has overwhelmed the word for nearly two years. Indonesia is one countries that been hit hard by Covid-19. Even though most of patients with positive test of Covid-19 had no symptoms or mild some of them reported persistent clinical symptoms months after test negative. This population with disorder whose terminology Long Covid-19 need health care to help them cope with this condition. In this need Department of Pulmonology and Respiratory medicine initiate community service activity for Covid-19 survival with Long Covid-19 in the formulation Hotline Service on Post Covid-19 Health Problem. Survivors of Covid-19 who accessed this service originated from variety geographic region in Indonesia. This Activity reached 60 survivors were mostly female (57%), in age group of young adult (62%) and dominant with mild symptoms (58%). Recommendation for these survivors whose mild symptoms was self care observation. There were still about 25 survivors (42%) who need further health care with appropriate speciality.
Pendampingan tata kelola Bumdes Tirto Desa Landungsari Dau Malang
Authors: Latifah Sri Wahjuni , Jati Ahmad Waluya 
Published: April 2022

Bumdes is a Village Owned Enterprise as Landungsari Village of Malang Regency has Bumdes Tirto. Of the various problems Bumdes Tirto Landungsari Village has several main problems, namely Bumdes does not have good governance, does not have long-term or short-term goals as a basis for carrying out its operational plan. Bumdes Tirto already has employees and people who work but do not have an organizational structure and job description. The impact is that Bumdes manager works alone and does not yet have a goal. The problem-solving solution offered to partners is done by training in the preparation of Organizational Structure and Job Description, socialization of the importance of work programs and training in creating work programs. Then conducted training and video creation Profile as a socialization stakeholders. Related to the improvement of the performance of the Village Market business unit, discussions have been conducted about the implementation procedures of online marketing. The purpose of this activity is the increasing knowledge of partner human resources about good governance in Bumdes and the establishment of a Blueprint consisting of long-term and short-term bumdes programs and the arrangement of bumdes profile videos as bumdes socialization media.
Pelatihan pemasaran produk BUMDesa berbasis digital di Kabupaten Bengkalis
Authors: Azlina Nur , Desmiyawati Desmiyawati , Azhar A Al , Nurulita Suci , Ramaiyanti Sinta , Humairoh Fitri , Amri Taqiyuddin 
Published: April 2022

This community service activity was carried out at the BUMDesa, Bengkalis District. The purpose of this community service activity is to 1) increase knowledge of the importance of the digital world for the development of BUMDesa, 2) encourage BUMDesa players to digitize the products offered, 3) introduce new marketing methods for BUMDesa players through the marketplace. The benefits of this community service activity are to increase the knowledge and ability of BUMDesa actors in utilizing digital technology in marketing BUMDesa product. The target audience for this activity are BUMDesa actors in the Bengkalis sub-district. The method used in community service activities is to use training methods for several BUMDesa in Bengkalis District. After the training activities have been carried out, the implementing team will follow up by forming a mentoring and coaching group for BUMDesa. The purpose of this follow-up is done offline and online using the zoom application, google meet, or can be via whatsapp. The purpose of holding a follow-up is to see the knowledge of BUMDesa and existing obstacles so that if there are obstacles, they can be handled immediately.
Produktivitas dan Nilai Ekonomi Ternak Ayam Pedaging dengan Penggunaan Jamu Herbal Siyuna
Authors: Susanto Adi , Widodo Wahyu , Rahayu Imbang Dwi , Devi A Apriliana 
Published: April 2022

Pertumbuhan ayam pedaging yang optimal ditentukan aspek genetik, lingkungan dan manajemen yang tepat, guna mengoptimalkan pertumbuhan sekaligus menghindari resistensi penggunaan antibiotic growth promotor (AGP) alternatifnya adalah pemberian feed additiveyang berupa jamu herbal, yang didalamnya terdapat dapat bahan aktif guna memperbaiki kondisi tubuh selama masa pemeliharaan.Penelitian dilakukan dalam Kandang Closed House. Materi penelitian DOC pedaging, pemberian jamu herbalSiyuna didalam pakan. Perlakuan pakan herbal 4 macam perlakuan yaitu; P0 : Pakan tanpa jamu herbal 0% (sebagai kontrol), P1: Pakan dengan 1 %, P2 : Pakan dengan 2 % dan P3 : Pakan dengan 3 %. dengan 5 ulangan.Penggunaan jamu herbal berpengaruh tidak nyata (P>0.05) terhadap produktivitas yang ditentukan berdasarkan bobot badan akhir. Nilai ekonomi berdasarkan penerimaan atau keuntungan, perlakuan terbaik pada perlakuan jamu herbal sebanyak 1 %(persen), apabila dilakukan diskriminasi harga atau pencapaian harga minimal agar penggunaan jamu herbal dapat memberikan keuntungan.
Misuse of antibiotics in Iraq: A review of Iraqi published studies
Authors: Khulood Saadoon Salim  , Atheer S. Alsabah  , Hassanian S. Taghi  
Published: April 2022

Misuse of antibiotics is one of the health problems worldwide. In Iraq, prevalence of self- medication with antibiotics increases resistant organisms, this will lead to bad impacts on health and economic aspects in the future. Aim of study is to review the published articles on the antibiotics misuse in Iraq, in

addition to assess the level of the population’s knowledge towards antibiotics misuse and the suggested recommendation to reduce this problem. Method: In this study 12 articles conducted in different regions of Iraq were reviewed to assess antibiotic misuse in a period from 2014-2020.Results: The results demonstrated high prevalence of antibiotic misuse among Iraqi population ranging from (45%- 92%). In addition, poor knowledge among population towards antibiotics misuse also reported. Bad attitudes of pharmacists and physicians regarding antibiotics prescribing and dispensing were registered. Conclusion: The review focuses on important health issue in Iraq that effect on health & economic system. New legislations and restriction need to apply to limit this problem.
Highlights on polymeric micelles as versatile nanocarriers for drug transporting
Authors: Hussein A. Abdul Hussein  , Nidhal K. Maraie  
Published: April 2022

Polymeric micelles are nanoscale core-shell structures formed by amphiphilic (block or graft) copolymers, that can self-aggregate in an aqueous medium. PMs characterized by small size, spherical shape, lower critical micellar concentration, which gave higher
stability for PMs over conventional surfactant micelles. The core/shell structure permits polymeric micelle to entrap poor soluble drugs and can improve their solubility and permeability. The preparation of PMs tends to be relatively easy as compared to other novel drug delivery systems. This review focus on the general properties, types, types of copolymer utilized, formation mechanism, preparation methods, characterization techniques, and the applications on PMs.
UU ITE Siap Menjerat Pengguna Media Sosial yang Tidak Bijak
Authors: Susilowati Endang yuliana , Irpan Y.B. 
Published: April 2022

This community service aims to understand, motivate, and invite the public, especially students of the Faculty of Law, Unisri Surakarta, to use social media wisely so as not to become perpetrators of criminal acts of violation of Law No. 11 of 2008 concerning Information and Electronic Transactions which was updated with Law No. 19 of 2016 .
Legal counseling is carried out online using the method of material presentation by the lecturer as a team of extension workers, followed by discussions, giving responses, opinions, impressions, messages or criticisms from participants who are present guided by students as moderators.
Knowing and understanding the existence of the ITE Law, especially regarding criminal acts using social media, it is hoped that students can participate in disseminating this information to people in their social circle as an effort to prevent the occurrence of criminal acts through the use of social media.
Российские публикации по библиотечно-информационным наукам в Scopus
Authors: Мохначева Ю. В. , Цветкова В. А. 
Published: April 2022

Рассмотрен подход на основе динамики употребляемости ключевых терминов в развитии научных тем по библиотечно-информационным наукам. Основная цель исследования – анализ сегмента российских публикаций по библиотечно-информационным наукам, а также выявление круга наиболее активно развивающихся тем с применением терминологического подхода и выявлением особенностей употребления ключевых терминов по базе данных Scopus на основе тем SciVal. Объектом исследования выбран массив публикаций российских авторов по библиотечно-информационным наукам за 2000–2020 гг. в Scopus. Метод исследования включал следующие основные действия: использование WoS CC для отбора публикаций в режиме расширенного поиска, систематизации по авторам и их ранжированию; далее на основе Scopus проведён поиск по выявленным в WoS CC авторам, составлены их соотношение и ранжирование в темах SciVal. Отобраны темы, в которых термины наиболее активно использовались. Основываясь на гипотезе: чем больше ключевых слов с динамикой больше 0% в теме, тем выше вероятность того, что эта тема перспективная и активно развивающаяся, и чем больше ключевых терминов в теме имеют отрицательную динамику, тем с большей вероятностью можно говорить о снижении интереса к ней со стороны исследователей. Определены наиболее перспективные темы российских исследований по библиотечно-информационным наукам. Наиболее перспективными оказались три темы: «Intellectual Structure; Co-citation Analysis; Scientometrics», «Hirsch Index; Self-Citation; Journal Impact Factor», «Co-Authorship; Scientific Collaboration; Scientometrics».
Самоцитирование и его влияние на оценку научной деятельности: обзор литературы. Часть II
Authors: Писляков В. В. 
Published: April 2022

Представлен обзор литературы, посвящённой влиянию самоцитирования и возникающим от этого возможным искажениям при библиометрическом анализе. Вводится обобщённое определение самоцитирования и его частных вариантов: авторского, институционального, странового, журнального, дисциплинарного, издательского. Приведены формулы основных метрик самоцитирования – коэффициентов самоцитирования и самоцитируемости. Подробно рассмотрена мировая литература по авторскому, институциональному, страновому и журнальному самоцитированию. Обобщены текущие взгляды на роль и влияние самоцитирования при оценке научной деятельности. При аналитическом рассмотрении статей, посвящённых самоцитированию, выясняется, что у исследователей существует консенсус по ряду позиций, например: а) патологией является как гипертрофированное самоцитирование, так и его отсутствие; б) самоцитирование мало влияет на оценку крупных научных единиц, но может быть критическим при анализе отдельных учёных; в) влияние самоцитирования наиболее выражено у научных единиц со слабыми библиометрическими показателями, в то время как топовые учёные, организации, журналы и др. получают наибольшее число ссылок извне. Рассмотрено реагирование самих библиометрических инструментов и баз данных с целью корректировки индикаторов в случае манипулирования самоцитированием.Вторая, заключительная часть обзора посвящена институциональному, страновому и журнальному самоцитированию, а также введению новых библиометрических индикаторов, так или иначе учитывающих наличие самоцитирования.
Community Impact on a Cryptocurrency: Twitter Comparison Example Between Dogecoin and Litecoin
Authors: Lansiaux Edouard , Tchagaspanian Noé , Forget Joachim 
Published: April 2022

Context: The third generation of cryptocurrencies gathers cryptocurrencies that are as diverse as the market is big (e.g., Dogecoin or Litecoin). While Dogecoin is seen as a memecoin, the other gathers a very different category of investors. To our knowledge, no study has independently assessed the crypto community’s economical impact on these cryptocurrencies. Furthermore, various methodological possibilities exist to forecast cryptocurrency price—mainly coming from online communities.Method: Our study has retrospectively studied (from 01/01/2015 to 03/11/2021)—using open access data—the association strength (using normalized mutual information) and the linear correlation (using Pearson’s correlation) between Twitter activity and cryptocurrency economical attributes. In addition, we have computed different models (ADF, ARIMA, and Interpretable MultiVvariable Long Short-Term Memory recurrent neural network) that forecast past price values and assessed their precision.Findings and conclusions: While the average Dogecoin transaction value is impacted by tweets, tweets are impacted by Litecoin transactions number and average Litecoin transaction value. Tweet number is impacted by Dogecoin whale behavior, but no significant relationship was found between Litecoin whales and tweets. The forecasting error resulting from our ARIMA (0,0,0) models was 0.08% (with Litecoin) and 0.22% (with Dogecoin). Therefore, those are just the beginning of scientific findings that may lead to building a trading robot based on these results. However, in itself, this study is only for academic discussion, and conclusions need to be drawn by further research. The authors cannot be liable if any financial investment is made based on its conclusions.
Maternal Protein Restriction Alters the Expression of Proteins Related to the Structure and Functioning of the Rat Offspring Epididymis in an Age-Dependent Manner
Authors: Cavariani Marilia Martins , de Mello Santos Talita , Chuffa Luiz Gustavo de Almeida , Pinheiro Patrícia Fernanda Felipe , Scarano Wellerson Rodrigo , Domeniconi Raquel Fantin 
Published: April 2022

Nutrition is an environmental factor able to activate physiological interactions between fetus and mother. Maternal protein restriction is able to alter sperm parameters associated with epididymal functions. Since correct development and functioning of the epididymides are fundamental for mammalian reproductive success, this study investigated the effects of maternal protein restriction on epididymal morphology and morphometry in rat offspring as well as on the expression of Src, Cldn-1, AR, ER, aromatase p450, and 5α-reductase in different stages of postnatal epididymal development. For this purpose, pregnant females were allocated to normal-protein (NP—17% protein) and low-protein (LP—6% protein) groups that received specific diets during gestation and lactation. After weaning, male offspring was provided only normal-protein diet until the ages of 21, 44, and 120 days, when they were euthanized and their epididymides collected. Maternal protein restriction decreased genital organs weight as well as crown-rump length and anogenital distance at all ages. Although the low-protein diet did not change the integrity of the epididymal epithelium, we observed decreases in tubular diameter, epithelial height and luminal diameter of the epididymal duct in 21-day-old LP animals. The maternal low-protein diet changed AR, ERα, ERβ, Src 416, and Src 527 expression in offspring epididymides in an age-dependent manner. Finally, maternal protein restriction increased Cldn-1 expression throughout the epididymides at all analyzed ages. Although some of these changes did not remain until adulthood, the insufficient supply of proteins in early life altered the structure and functioning of the epididymis in important periods of postnatal development.
Hemodynamic Changes During Physiological and Pharmacological Stress Testing in Patients With Heart Failure: A Systematic Review and Meta-Analysis
Authors: Bingel Anne , Messroghli Daniel , Weimar Andreas , Runte Kilian , Salcher-Konrad Maximilian , Kelle Sebastian , Pieske Burkert , Berger Felix , Kuehne Titus , Goubergrits Leonid , Fuerstenau Daniel , Kelm Marcus 
Published: April 2022

Although disease etiologies differ, heart failure patients with preserved and reduced ejection fraction (HFpEF and HFrEF, respectively) both present with clinical symptoms when under stress and impaired exercise capacity. The extent to which the adaptation of heart rate (HR), stroke volume (SV), and cardiac output (CO) under stress conditions is altered can be quantified by stress testing in conjunction with imaging methods and may help to detect the diminishment in a patient’s condition early. The aim of this meta-analysis was to quantify hemodynamic changes during physiological and pharmacological stress testing in patients with HF. A systematic literature search (PROSPERO 2020:CRD42020161212) in MEDLINE was conducted to assess hemodynamic changes under dynamic and pharmacological stress testing at different stress intensities in HFpEF and HFrEF patients. Pooled mean changes were estimated using a random effects model. Altogether, 140 study arms with 7,248 exercise tests were analyzed. High-intensity dynamic stress testing represented 73% of these data (70 study arms with 5,318 exercise tests), where: HR increased by 45.69 bpm (95% CI 44.51–46.88; I2 = 98.4%), SV by 13.49 ml (95% CI 6.87–20.10; I2 = 68.5%), and CO by 3.41 L/min (95% CI 2.86–3.95; I2 = 86.3%). No significant differences between HFrEF and HFpEF groups were found. Despite the limited availability of comparative studies, these reference values can help to estimate the expected hemodynamic responses in patients with HF. No differences in chronotropic reactions, changes in SV, or CO were found between HFrEF and HFpEF. When compared to healthy individuals, exercise tolerance, as well as associated HR and CO changes under moderate-high dynamic stress, was substantially impaired in both HF groups. This may contribute to a better disease understanding, future study planning, and patient-specific predictive models.Systematic Review Registration[https://www.crd.york.ac.uk/prospero/], identifier [CRD42020161212].
Correlation Between Plasma Proteomics and Adverse Outcomes Among Older Men With Chronic Coronary Syndrome
Authors: Cai Yu-Lun , Hao Ben-Chuan , Chen Jian-Qiao , Li Yue-Rui , Liu Hong-Bin 
Published: April 2022

BackgroundChronic coronary syndrome (CCS) is a newly proposed concept and is hallmarked by more long-term major adverse cardiovascular events (MACEs), calling for accurate prognostic biomarkers for initial risk stratification.MethodsData-independent acquisition liquid chromatography tandem mass spectrometry (DIA LC-MS/MS) quantitative proteomics was performed on 38 patients with CCS; 19 in the CCS events group and 19 in the non-events group as the controls. We also developed a machine-learning-based pipeline to identify proteins as potential biomarkers and validated the target proteins by enzyme-linked immunosorbent assay in an independent prospective cohort.ResultsFifty-seven differentially expressed proteins were identified by quantitative proteomics and three final biomarkers were preliminarily selected from the machine-learning-based pipeline. Further validation with the prospective cohort showed that endothelial protein C receptor (EPCR) and cholesteryl ester transfer protein (CETP) levels at admission were significantly higher in the CCS events group than they were in the non-events group, whereas the carboxypeptidase B2 (CPB2) level was similar in the two groups. In the Cox survival analysis, EPCR and CETP were independent risk factors for MACEs. We constructed a new prognostic model by combining the Framingham coronary heart disease (CHD) risk model with EPCR and CETP levels. This new model significantly improved the C-statistics for MACE prediction compared with that of the Framingham CHD risk model alone.ConclusionPlasma proteomics was used to find biomarkers of predicting MACEs in patients with CCS. EPCR and CETP were identified as promising prognostic biomarkers for CCS.
Restoring Impaired Fertility Through Diet: Observations of Switching From High-Fat Diet During Puberty to Normal Diet in Adulthood Among Obese Male Mice
Authors: Qi Xiangyu , Zhang Meijie , Sun Mingqi , Luo Dandan , Guan Qingbo , Yu Chunxiao 
Published: April 2022

BackgroundObesity is associated with a decrease in testicular function, yet the effects and mechanisms relative to different stages of sexual development remain unclear. The aim of this study is to determine whether high-fat diet-induced obesity impairs male fertility during puberty and in adulthood, and to ascertain its underlying mechanisms. This study aims to further reveal whether restoring to a normal diet can improve impaired fertility.MethodsMale mice were divided into 6 groups: the group N and H exposed to a normal diet or high-fat diet during puberty. The group NN or NH were further maintained a normal diet or exposed to high-fat diet in adulthood, the group HH or HN were further maintained high-fat diet or switched to normal diet in adulthood. Metabolic parameters, fertility parameters, testicular function parameters, TUNEL staining and testicular function-related proteins were evaluated, respectively.ResultsThe fertility of the mice in the high-fat diet group was impaired, which validated by declines in pregnancy rates and litter weight loss. Further analysis demonstrated the increased level of oxidative stress, the increased number of spermatogenic cell apoptosis and decreased number of sperm and decreased acrosome integrity. The expression of steroidogenic acute regulatory (StAR) and spermatogenesis related proteins (WT-1) decreased. Fertility among the HN group recovered, accompanied by the recovery of metabolism, fertility and testicular function parameters, StAR and WT-1 expression.ConclusionsThe findings suggest that high-fat diet-induced obesity impairs male fertility during puberty and in adulthood. The loss of acrosome integrity, the increase of oxidative stress, the increase of cells apoptosis and the down-regulation of StAR and WT-1 may be the underlying mechanisms. Switching from high-fat diets during puberty to normal diets in adulthood can improve male fertility.