bluuebunny/crossref_metadata_2025_split huggingface dataset:
Plastic Waste Mitigation Strategies: A Review of Lessons from Developing Countries
Authors: Hira Anil , Pacini Henrique , Attafuah-Wadee Kweku , Vivas-Eugui David , Saltzberg Michael , Yeoh Tze Ni 
Published: July 2022

Global plastics waste is an issue of ever-increasing urgency. Estimates suggest some 79% of plastic waste is dumped into the environment, where it is likely to have devastating effects on ecosystems and human health. Marine plastic pollution is a particularly challenging issue, as plastics take decades to break down, and do so into micro- and nanoparticles that affect marine ecosystems and the food web. The plastics pollution problem is magnified in the Global South, where rising production and consumption coexist with underdeveloped waste treatment systems and large volumes of imported plastic waste. This article examines the reasons for the failure to curb plastic waste in Sub-Saharan Africa (SSA) and South Asia (SA), target regions of the Sustainable Manufacturing and Environmental Pollution (SMEP) program funded to address such issues. The article examines the challenges in shifting manufacturing processes and natural materials substitution for reducing plastics waste. It recommends greater external financial and technical support for waste treatment, stakeholder consensus and awareness-building, regulatory policies that reduce the price and convenience differentials between plastics and substitute materials, and a push towards enforcement of environmental regulations.
Determinants of survival in patients on extracorporeal membrane oxygenation therapy due to severe covid-19
Authors: Natanov Ruslan , Kunkel Elena R. , Wiesner Olaf , Haverich Axel , Wiegmann Bettina , Rümke Stefan , Kühn Christian 
Published: July 2022

Background Severe acute respiratory distress syndrome (ARDS) due to Coronavirus Disease-19 (COVID-19) is associated with high mortality. Although survival on mechanical circulatory support has improved, determinants for better prognosis are still unclear. Here, we report on the outcome of our patient population with the need for mechanical circulatory support due to severe COVID-19 (sCOVID-19) induced ARDS. Methods All patients treated with extracorporeal membrane oxygenation (ECMO) for severe ARDS due to sCOVID-19 were analysed. Patients > 18 years of age at the time of initiation of ECMO were included. Pre-existing comorbidities, complications during ECMO implantation, and ECMO runtime were reviewed. The latency to intubation, proning, tracheotomy, and ECMO implantation was analysed. Furthermore, the survival and non-survival population were compared to determine factors in favour of a better outcome. Results In total, 85 patients were treated with veno-venous membrane oxygenation (vv-ECMO) for severe ARDS in our medical centre. The patient population was predominantly male (83.5%) with a mean patient age of 54.9 years. A history of cardiovascular disease ( p = .01), smoking ( p < .05), need for vasopressor- ( p < .05), and renal replacement therapy ( p < .001) was associated with a worse prognosis. Overall survival was 50%. The survival population was significantly younger ( p = .004), had a significantly higher body weight ( p = .02) and body mass index (BMI) ( p = .01). Furthermore, survival was significantly better when vv-ECMO was initiated within 48 h after admission ( p < .001). Conclusions Pre-existing cardiovascular disease, higher age, history of nicotine abuse, and development of renal failure are associated with poor outcome. Early start of vv-ECMO therapy may lead to better survival in sCOVID-19 patients, although complications during ECMO therapy are associated with a worse prognosis.
Effectiveness of custom-made functional foot orthoses versus flat cushioning insoles on pain in patients with systemic lupus erythematosus
Authors: Palomo-Toucedo Inmaculada C , Domínguez-Maldonado Gabriel , Reina-Bueno María , Vázquez-Bautista María del Carmen , Castillo-López José Manuel , Ramos-Ortega Javier , Munuera-Martínez Pedro V 
Published: July 2022

ObjectiveTo determine the effect of foot orthoses on pain, disability and foot functionality in patients with Systemic Lupus Erythematosus.DesignRandomized clinical trial.SettingUniversity Podiatric Clinical Area.SubjectsPatients with systemic lupus erythematosus.InterventionsPatients were randomly assigned to either group A, which received custom-made functional foot orthoses, or group B, which received flat cushioning insoles, for three months.Main measuresThe primary outcome was foot pain, measured by 11-point numeric pain rating scale. Foot functionality and foot-related disability were evaluated using the foot function index, the Manchester foot pain and disability, at the beginning and at days 90.ResultsSixty-six participants (age 47.3 ± 11.9 years) suffering from foot pain, received either the custom-made foot orthoses ( N = 33) or the flat cushioning insoles ( N = 33). For the analysis of the data, only participants who had finished the follow-up period (90 days) were included. None statistically significant difference between groups were found. In group A, all variables showed statistically significant differences when comparing the initial and final measurements. Pain showed 6.8 ± 1.6 and 4.2 ± 2.9 in group A, at baseline and at 90 days, respectively, group B showed 6.5 ± 1.5 and 4.7 ± 3.0 at baseline and at 90 days, respectively.ConclusionBoth groups showed a reduction in foot pain. This study suggests that not only controlling the foot function, but providing cushioning to the foot, may have positive effects to manage foot pain in patients with systemic lupus erythematosus.
Alliance Thérapeutique Entre Les Patients Hospitalisés En Psychiatrie De Secteur Et Les Infirmier(e)s Et Aide-Soignant(e)s: Une Etude Prospective, Observationnelle Et Transversale
Authors: Morvillers Jean-Manuel , Roy Carine , Laouénan Cédric , Goutté Nathalie 
Published: July 2022

Contexte L’alliance thérapeutique représente un objet très peu étudié quand il concerne les infirmiers et les soins prodigués par une équipe infirmière et dans le cadre de l’hospitalisation en soins aigus. Objectif L’objectif était d’étudier l’influence de facteurs sur l’alliance thérapeutique construite entre les infirmier(e)s et les aides-soignant(e)s et les patients adultes hospitalisés dans un service de soins aigus en psychiatrie générale de secteur. Méthode Il s’agit d’une étude prospective, observationnelle et transversale utilisant une échelle de mesure de l’alliance thérapeutique. Le score d’alliance thérapeutique (AT) a été mesuré à l’aide de l’échelle STAR-P sur un échantillon de 240 patients. Résultats Le score moyen obtenu est de 33,4 (±7,8) sur un score maximum théorique de 48. Le score global d’AT des patients âgés de 60 ans ou plus, est significativement plus élevé que celui des patients ayant entre 18 et 29 ans ( p = 0,021). L’absence de suivi ambulatoire au cours des trois mois suivant la sortie d’hospitalisation n’est pas associée au score global d’AT ( p = 0,73). Si les patients hospitalisés, quelques soit leurs troubles et les différentes formes de soins, sous obligation légale ou non, jugent plutôt bonne l’AT à l’issue de leur hospitalisation. Seuls des facteurs sociaux-démographiques comme, l’âge, les conditions d’hébergement (précaire ou durable), avoir ou non un emploi, vivre seul ou avec un partenaire influent sur l’AT et le suivi. Conclusion Les résultats convoquent les concepts d’anomie et d’attachement, qui semblent jouer un rôle important dans l’absence de suivi post-hospitalisation, ce qui indiquent la nécessaire approche globale des soins et une implication des professionnels de santé mais aussi du social où l’empathie doit trouver sa place.
Vaping and Sleep as Predictors of Adolescent Suicidality
Authors: Welty Cody W. , Gerald Lynn B. , Nair Uma S. , Haynes Patricia L. 
Published: July 2022

Purpose To investigate sleep quantity as a moderator of vaping and self-reported suicidality among adolescents. Design Cross-sectional. Setting: United States high schools. Sample 10,520 high-school students with complete data on the primary outcome of suicide attempt in the past year (76.9% response rate). Measures 2019 Youth Risk Behaviors Survey. Analysis Logistic regression to examine main effects and potential moderation. Results Students with under seven sleep hours on school nights (OR = 2.6; 95% CI = 2.1-3.3) and who vaped in the past month (OR = 3.0; 95% CI = 2.1-3.9) had higher odds of attempting suicide in the last year. Sleep quantity moderated the relationship between vaping and suicidal thoughts in the past year (P = .01) but did not moderate the relationship between vaping and a suicide plan ( P = .15) or suicide attempts ( P = .06). Specifically, vaping had a smaller effect on suicidal thoughts among students who slept under seven hours on school nights (OR = 1.8) compared to the descriptively larger effect among participants with more sleep (OR = 2.5). Conclusions Students who vape or report low sleep quantity would be ideal participants in suicide prevention interventions as they may be at higher risk for suicidality. Organizations implementing sleep or vaping interventions should incorporate information regarding the higher odds of suicide among students with low sleep quantity or vaping habits.
A systematic review and meta-analysis of the evidence for community-based HIV testing on men’s engagement in the HIV care cascade
Authors: Groves Allison K , Stankard Petra , Bowler Sarah L , Jamil Muhammad S , Gebrekristos Luwam T , Smith Patrick D , Quinn Caitlin , Ba Ndoungou Salla , Chidarikire Thato , Nguyen Van Thi Thuy , Baggaley Rachel , Johnson Cheryl 
Published: July 2022

Objective Men with HIV are less likely than women to know their status, be on antiretroviral therapy, and be virally suppressed. This review examined men’s community-based HIV testing services (CB-HTS) outcomes. Design Systematic review and meta-analysis. Methods We searched seven databases and conference abstracts through July 2018. We estimated pooled proportions and/or risk ratios (for meta-analyses) for each outcome using random effects models. Results 188 studies met inclusion criteria. Common testing models included targeted outreach (e.g. mobile testing), home-based testing, and testing at stand-alone community sites. Across 25 studies reporting uptake, 81% (CI: 75–86%) of men offered testing accepted it. Uptake was higher among men reached through CB-HTS than facility-based HTS (RR = 1.39; CI: 1.13–1.71). Over 69% (CI: 64–71%) of those tested through CB-HTS were men, across 184 studies. Across studies reporting new HIV-positivity among men ( n = 18), 96% were newly diagnosed (CI: 77–100%). Across studies reporting linkage to HIV care ( n = 8), 70% (CI: 36–103%) of men were linked to care. Across 57 studies reporting sex-disaggregated data for CB-HTS conducted among key populations, men’s uptake was high (80%; CI: 70–88%) and nearly all were newly diagnosed and linked to care (95%; CI: 94–100%; and 94%; CI: 88–100%, respectively). Conclusion CB-HTS is an important strategy for reaching undiagnosed men with HIV from the general population and key population groups, particularly using targeted outreach models. When compared to facility-based HIV testing services, men tested through CB-HTS are more likely to uptake testing, and nearly all men who tested positive through CB-HTS were newly diagnosed. Linkage to care may be a challenge following CB-HTS, and greater efforts and research are needed to effectively implement testing strategies that facilitate rapid ART initiation and linkage to prevention services.
“A service we know was missing”: bridging the gap between referral to admission for women with moderate-severe perinatal mental health disorders at an Australian psychiatric mother-baby unit
Authors: Beaumont Tara , Sved-Williams Anne , Hill Rebecca 
Published: July 2022

Objectives Service demand at Australian psychiatric mother-baby units is high. This project aimed to test a model of care providing step up/step down support to women with moderate-severe perinatal mental health disorders awaiting hospital admission. Method A multi-disciplinary team was convened to provide pre-admission assessment and support to women waiting for admission, as well as post-discharge support as needed. Results 108 referrals were managed between April – November 2021. With appropriate assessment and/or support in place, half of the women referred ( n = 54/108) were removed from the waitlist and avoided hospital admission. Service capacity indicators suggest a positive impact on referral numbers managed each week, as well as admissions per month. Conclusion The tested model of care appears to have successfully improved service capacity; however longer term data is recommended to determine the sustainability of the trend towards increased capacity, and the acceptability of the model of care from a consumer perspective.
Raising a Child with Craniosynostosis: Psychosocial Adjustment in Caregivers
Authors: Costa Bruna , Edwards Wendy , Wilkinson-Bell Karen , Stock Nicola Marie 
Published: July 2022

Objective While knowledge of the psychosocial impact of craniofacial conditions is growing, literature regarding the impact on parents remains limited. Parents of children born with a health condition may be at risk of experiencing a range of psychosocial challenges. This study conducted an initial investigation of psychosocial adjustment of parents of individuals with craniosynostosis to inform support provision for families. Setting An online UK-wide mixed-methods survey was distributed to members of Headlines Craniofacial Support. Design Quantitative data including standardized measures were analysed using descriptive statistics and independent samples t-tests, and inductive content analysis was used for open-ended questions. Participants Mothers (n  =  109) and fathers (n  =  9) of individuals ages 3 months to 49 years with single suture (63%) or syndromic (33%) craniosynostosis participated. Results Compared to the general population, parents of individuals with craniosynostosis reported higher levels of stress, anxiety, and depression; lower levels of resilience and optimism. Qualitative responses provided insight into parents’ experiences of birth, diagnosis, healthcare provision, familial wellbeing, and relationships. Parents reported several unmet information and support needs, alongside a range of positive outcomes. Conclusions This study illustrates the potential long-term psychosocial implications for parents raising children with craniosynostosis. There is a need for routine psychological screening for family members and provision of appropriate psychological support for those at risk for distress. Non-specialist health professionals may benefit from additional training about craniofacial conditions so they are better equipped to support and refer families.
Long-term Follow-up of 254 Ceramic Coated Implant (CCI) Evolution Total Ankle Replacements
Authors: van Es Laurian J. M. , van der Plaat Laurens W. , Sierevelt Inger N. , Hoornenborg Daniel , Haverkamp Daniel 
Published: July 2022

Background: The ceramic coated implant (CCI) Evolution was a third-generation implant design used in approximately 2000 total ankle replacements (TARs) between 2003 and 2016. Because this implant was abandoned, long-term follow-up studies are lacking. Methods: All patients undergoing TAR using a CCI prosthesis between 2004 and 2012 were included for analysis. Preoperatively the tibiotalar alignment was measured, and postoperatively the patients were followed up clinically, with radiographs and by questionnaire. The primary outcome was implant survival at 10 years of follow-up. Implant survival was also compared for (1) inflammatory joint disease vs noninflammatory joint disease and (2) preoperative tibiotalar neutral vs varus or valgus alignment. The secondary outcomes were complications, reoperations, and function (assessed by patient-reported outcome measures). Results: Two hundred fifty-four TARs were performed in 237 patients. Two hundred twelve additional procedures were performed to achieve stable ankles. At 10-year follow-up, the survival was 67.5%, with an average time to revision of 4.5 years. The 10-year survival of the inflammatory joint disease group was 76.8% and of the noninflammatory joint group 63.1% ( P = .44). In 248 TARs, the preoperative tibiotalar alignment was measured; (62% neutral, 25% varus, and 13% valgus), these showed 10-year survival rates of 74.7%, 48.2%, and 68.9% respectively ( P = .07). The complication rate was 54%; 37% of patients underwent reoperation. At a mean of 8.5 years, postoperative satisfaction scored an average of 7.0 (SD 2.26) on a 0- to 10-point numeric rating scale. The mean Foot and Ankle Ability Measure sports subscore was 24.7, the mean Foot and Ankle Outcome Score (FAOS) sports subscore was 42.8, and the mean 36-Item Short Form Health Survey score was 40.0. Regarding daily activities, the mean FAOS was 81.0. Conclusion: This is currently the sole study reporting the long-term results of the CCI prosthesis. The survival and functional outcomes were inferior to other third-generation mobile-bearing ankle implants.
Chinese Cancer Patients’ Attitudes Toward Psychotherapy and Their Willingness to Participate in Clinical Trials of Psychotherapy
Authors: Zeng Zhi , Deng Yaotiao , Liu Jie , Yang Keyi , Peng Hu , Jiang Yu 
Published: July 2022

Introduction Psychotherapy is considered part of the standard treatment of cancer in Western countries. However, there is no literature on the attitudes of Chinese cancer patients toward psychotherapy. Methods: In a multicenter, cross-sectional study in China, a homemade questionnaire was delivered to cancer patients. The targeted population was Chinese hospitalized cancer patients who were informed of their state of illness. Results Five hundred and fifty cancer patients received our questionnaire, and 83.3% completed the questionnaire. Among the 458 patients, 43.2% indicated that they had never heard of psychotherapy before the survey. However, after a brief introduction of psychotherapy, most (92.1%) cancer patients indicated that psychotherapy is essential for cancer patients, and over half of patients (57.4%) were willing to take psychotherapy on the advice of the oncologist in charge. Participants aged 45 years or younger, had a family income > 10000 yuan per month, and had an ECOG PS (Eastern Cooperative Oncology Group Performance Status) of 2-4 were more willing to receive psychotherapy. Of all patients, 59.2% and 57.6% were willing to participate in individual and group psychotherapy clinical trials, respectively. Participants who had a bachelor’s degree or higher (odds ratio, OR = 2.09) and were aged 45 years or younger (OR = 1.67) were more willing to participate in individual and group psychotherapy clinical trials, respectively. Conclusion The unmet psychological needs of cancer patients in China remain high, and doctors’ advice is likely to positively impact the patients’ acceptance of psychotherapy. Psychological education for Chinese cancer patients should be strengthened. More high-quality clinical trials of psychotherapy should be conducted in China to achieve greater benefits for cancer patients and their families.
Asymptomatic unilateral phrenic nerve palsy after bortezomib treatment in a newly diagnosed multiple myeloma patient
Authors: Coşkunpınar Muharrem , Erdoğdu Batuhan , Goker Hakan 
Published: July 2022

Introduction Bortezomib is the first chemotherapeutic agent of proteosome inhibitor class that can be used in newly diagnosed and relapsed/refractory multiple myeloma. It is well known that bortezomib has side effects such as peripheral sensory, motor, or autonomic neuropathy. In this paper, we will present our patient who developed unilateral phrenic nerve palsy as an autonomic neuropathy after six cycles of subcutaneous bortezomib treatment. This case differs from other cases in that our patient was asymptomatic. Case report A 57-year-old male patient was admitted with back pain and gait disturbances. In the thorax computed tomography, a soft tissue mass causing compression on the spinal canal was observed in the T12 vertebra. Bone biopsy pathology report resulted in diffuse plasma cell infiltration. The patient was diagnosed with stage ISS-3, IgG kappa type multiple myeloma. Management and outcome Subcutaneous bortezomib 1 × 2.2 mg (Days 1-4-8-11) + intravenous cyclophosphamide 1000 mg (Day 1) + intravenous dexamethasone 40 mg (Days 1-2-3-4) (VCD chemotherapy protocol) was started. Totally six cycles of VCD were administered. While the patient did not have any respiratory symptoms, an elevation consistent with phrenic nerve palsy was observed in the left hemidiaphragm in the thorax computed tomography that was taken during the preparation for autologous hematopoietic stem cell transplantation. Discussion Bortezomib is a frequently used chemotherapeutic agent in patients with multiple myeloma and care should be taken in terms of the risk of developing phrenic nerve palsy in patients. There are cases of autonomic neuropathy developing after bortezomib treatment.
Late onset of a persistent, deep stromal and endothelial scarring after corneal collagen crosslinking for keratoconus: A case report
Authors: Fuchs Barbara , Wendelstein Jascha , Mariacher Siegfried , Tetz Kristin , Bolz Matthias , Fischinger Isaak 
Published: July 2022

Introduction To report a late onset, deep stromal and endothelial corneal scar in a keratoconus patient after corneal collagen cross-linking (CXL). Case description Observational case report. A 29-year-old man with bilateral keratoconus received an accelerated (A-CXL 10*9) epithelium-off CXL procedure in the left eye. 6-months postoperatively, a 2.2 × 1.2 mm inferocentral corneal scar was detected, which was located in the posterior stroma ranging from approximately 350 µm until the endothelium, therefore was situated below the demarcation line. A topical corticosteroid treatment did not influence the magnitude or configuration of the scar. Visual acuity was never affected, which includes the examination 12 months postoperatively. Conclusions We report a case of a late onset deep stromal and endothelial corneal scar 6 months after accelerated CXL as postoperative complication without affecting visual acuity.
Anastomotic Pseudoaneurysm in Kidney Transplant: A Challenging Management for a Rare Entity
Authors: Maritati Federica , Pini Rodolfo , Comai Giorgia , Bini Claudia , Corradetti Valeria , Mattiotti Maria , Ravaioli Matteo , Pini Alessia , La Manna Gaetano , Gargiulo Mauro 
Published: July 2022

Purpose: Anastomotic pseudoaneurysms of transplanted kidneys are a very rare complication encountered in less than 1% of cases. They may be devastating, leading to functional impairment, kidney transplantectomy, or death. Treatment has not been standardized, with open surgical repair considered the safest procedure even if it is often complicated by bleeding and graft loss. The purpose of this case report is to describe an endovascular treatment of this condition, consisting of the combination of coil embolization and arterial stenting. Case report: A 61-year-old woman developed an anastomotic pseudoaneurysm 2 months after kidney transplantation, causing acute kidney injury related to ab-extrinsic stenosis of the transplant renal artery (TRA) and external iliac artery. The pseudoaneurysm was successfully treated by coil embolization, and the arterial patency was restored by the stenting of TRA and external iliac artery. The patient completely recovered kidney function, and after a 6-month-follow-up, creatinine values were stable with normal renal perfusion. Conclusion: Endovascular repair through coil embolization and TRA stenting can be a safe and effective option to treat anastomotic pseudoaneurysm in kidney transplant.