bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bioanalytical method Development and Validation for Estimation of Olanzapine in K3edta Human Plasma by Liquid Chromatography–Tandem Mass Spectrometry and Application to a Pharmacokinetic Study
Authors: Malviya Jitendra , Joshi Deshbandhu , Bhadauria Raghvendra Singh 
Published: May 2022

A rapid and sensitive LC–MS/MS method for the bioanalytical method development and validation for estimation of olanzapine in k3EDTA human plasma using Olanzapine D3 as internal standard has been developed and validated. The analytes and IS were extracted from plasma by solid phase extraction using Oasis HLB 1cc (30mg) Extraction Cartridge and separated on a Cosmosil, 5µm, C18 150*4. 6 mmcolumn using a 10 mM ammonium formate in Water: Acetonitrile (10: 90) at a flow rate of 1.0 mL/min. Detection involved an API-4000 LC–MS/MS with electrospray ionization in the positive ion mode and multiple-reaction monitoring for analysis. The method was validated according to FDA guidelines and shown to provide intra- and inter-day precision and accuracy within acceptable limits in a run time of only 4.0 min. The method was successfully applied to a pharmacokinetic study involving a single oral administration of a combination tablet to human male volunteers
Countering master narratives with narratives of persistence: A liberation perspective in career counseling
Authors: Sensoy-Briddick Hande , Briddick William C. 
Published: May 2022

As of 2019, the global youth population between the ages of 15 and 24 was 1.2 billion and growing (UNDESA, 2019). A sizable number of youth face discrimination and marginalization daily, often based on their social identities and related interlocking systems of power and oppression (Brewster & Molina, 2021). Minoritized youth, particularly, find themselves trapped in culturally manufactured master narratives that serve to reproduce the very systems of privilege that exist in their country (Liu, 2017). Considering these master narratives can be a significant step in our work with marginalized youth. Building on the contributions of leading scholars in career counselling, as well as other historically influential scholars in fields such as philosophy, education, and literature, we propose using narrative counselling and its related concepts to dismantle master narratives. In doing so, open spaces can emerge for alternative stories for the hopes, dreams, and futures of marginalized youth.
Keywords: Career; Master Narratives; Narrative Career Counselling
Revitalising career counseling for sustainable decent work and decent lives: From personality traits to life project reflexivity for well-being
Authors: Di Fabio Annamaria , Svicher Andrea , Palazzeschi Letizia , Gori Alessio 
Published: May 2022

The context of contemporary work scenarios features constant change and innovation in the field of information and communication technologies, which result in frequent work transitions and job insecurity. Such circumstances are highly threatening to the well-being of workers. Moreover, the instability and precariousness of the labour market are aggravated by the current crisis of the COVID-19 pandemic. Individuals are facing increased critical life and professional challenges and are being asked to take personal responsibility for the direction of their personal and work lives. In this complex context, career counseling needs to be revitalised in strength-based prevention perspectives. Life Project Reflexivity (LPR) addresses future professional and life plans and represents a critical construct for career counseling. The present study among Italian university students in transition to the labour market analysed the relationships between LPR and well-being while controlling for the ‘Big Five’ personality traits. The Big Five Questionnaire, the Life Project Reflexivity Scale and measures of both hedonic and eudaimonic well-being were administered to 278 university students of the University of Florence. LPR and its dimensions of authenticity, no acquiescence and clarity/projectuality explained the incremental variance beyond personality traits with respect to both hedonic and eudaimonic well-being, with specific reference to meaning in life. Among the three dimensions of LPR, authenticity was the most promising in this study. These results offered new perspectives for career counseling by supporting a strength-based prevention process for constructing sustainable decent work and life.

Keywords: career counseling; decent lives; decent work; life project reflexivity; well-being.
IMPACT OF CORPORATE SOCIAL RESPONSIBILITY, GENERAL ATTITUDE, TRUST AND PERCEIVED CONSUMER EFFECTIVENESS ON PURCHASE INTENTION (CASE OF H&M CUSTOMERS IN JABODETABEK)
Authors: Gunawan Valerie Aurora , Bernarto Innocentius 
Published: May 2022

<p>This study aims to analyze the positive influence of corporate social responsibility on purchase intention through trust, general attitude, and perceived consumer effectiveness. The survey method was implemented in this study. Data was collected using a questionnaire instrument. The target population is all customers who have shopped at H&amp;M in the Jabodetabek area. The number of samples is 400 respondents. The sampling technique was done by convenience sampling. Data analysis with Partial least Square-Structural Equation Modeling approach with the help of SmartPLS 3.0 program. The results show that corporate social responsibility has a positive effect on general attitude, trust, and perceived consumer effectiveness. Likewise, general attitude, trust, and perceived consumer effectiveness have a positive effect on purchase intention.</p><p><strong>BAHASA INDONESIA ABSTRACT</strong></p><p>Penelitian ini bertujuan untuk menganalisis pengaruh positif <em>corporate social responsibility </em>terhadap purchase intention melalui<em> trust</em>, <em>general attitude</em>, dan <em>perceived consumer effectiveness</em>. Metode survei diimplementasikan dalam penelitian ini. Pengumpulan data dilakukan dengan menggunakan instrumen kuesioner. Target populasi adalah semua pelanggan yang pernah berbelanja di H&amp;M wilayah Jabodetabek. Jumlah sampel sebesar 400 responden. Teknik pengambilan sampel dilakukan dengan <em>convenience sampling.</em> Analisis data dengan pendekatan <em>Partial least Square-Structural Equation Modeling</em> dengan bantuan program <em>SmartPLS 3.0</em>. Hasil penelitian menunjukan bahwa <em>corporate social responsibility</em> berpengaruh positif terhadap <em>general attitude</em>, <em>trust</em>, dan<em> perceived consumer effectiveness. </em>Begitu juga, <em>general attitude</em>, <em>trust</em>,<em> </em>dan<em> perceived consumer effectiveness</em> berpengaruh positif terhadap <em>purchase intention.</em></p>
Lateral Ulnar Collateral Ligament of the Elbow Joint
Authors: Fukai Atsuhiro , Nimura Akimoto , Tsutsumi Masahiro , Fujishiro Hitomi , Fujita Koji , Imatani Junya , Akita Keiichi 
Published: May 2022

Background:
To improve the clinical results of lateral ulnar collateral ligament (LUCL) reconstruction of the elbow joint, better understanding of the anatomy of the aponeuroses and joint capsule could be relevant. This study considers the previously described anatomy of the LUCL in relation to the related aponeuroses and joint capsule rather than as a discrete ligament. We hypothesized that the deep aponeuroses of the superficial extensor muscles and supinator form a relevant portion of the joint capsule previously defined as the LUCL.

Methods:
Twenty-four elbows (12 right) from 21 embalmed cadavers (age at the time of death, 54 to 99 years) were included in the study. Twenty elbows were studied macroscopically and 4, histologically. The joint capsule was detached from the bones, and local thickness was quantitatively analyzed using micro-computed tomography (micro-CT).

Results:
The supinator aponeurosis and joint capsule intermingled to form a thick membrane (mean and standard deviation, 4.8 ± 1.2 mm), which we termed “the capsulo-aponeurotic membrane.” It was thicker than the anterior (1.3 ± 0.4 mm) and posterior (2.5 ± 0.9 mm) parts of the capsule of the humeroradial joint (p < 0.001). The capsulo-aponeurotic membrane had a wide attachment on the distal part of the extensor digitorum communis and extensor digiti minimi (EDC/EDM) origin of the humerus, the lateral part of the coronoid process, and the posterior part of the radial notch of the ulna. The humeral attachment had a fibrocartilaginous structure. The deep aponeuroses of the EDC and extensor carpi ulnaris (ECU) were connected to the capsulo-aponeurotic membrane.

Conclusions:
The capsulo-aponeurotic membrane was composed of the supinator aponeurosis and joint capsule and was attached to the lateral epicondyle of the humerus, radial side of the coronoid process, and posterior part of the radial notch on the ulna. The entire structure appeared identical to the commonly defined lateral collateral ligament. The most posterior part was connected to the EDC and ECU aponeuroses, which is commonly labeled the LUCL but does not exist as a discrete ligament.

Clinical Relevance:
Consideration of the accurate anatomy of the extensive attachment of the capsulo-aponeurotic membrane could provide useful clues for improvement in techniques of LUCL reconstruction and lateral epicondylitis pathology.
Determination of Reasonable Bottom-Hole Pressure in Unconventional Tight Oil Reservoirs: A Field Case Investigation
Authors: Zhou Xiaofeng , Wei Jianguang , Zhang Ao , Zhang Xin , Rong Gen , Chen Yongda 
Published: May 2022

Abstract
The bottom-hole flow pressure is an important factor affecting the production of the unconventional tight oil well. The reasonable bottom-hole flow pressure has a positive effect on enhancing the production capacity of oilfields and improving the production efficiency of oilfield enterprises. Therefore, a robust method is proposed to determine the reasonable bottom-hole flow pressure in unconventional tight oil reservoirs, sharing the advantages of coupling geological feature and fluid flow behavior. In this method, the geological model and numerical reservoir simulation based on ECLIPSE software are developed firstly. The effects of the stress sensitivity, the PVT properties, permeability damage, fracturing fluid leak-off, and skin coefficient on the single-well productivity are then discussed. The reasonable variation range of the bottom-hole flow pressure in different production stages is then determined. Results show that crude oil viscosity, formation damage, and stress sensitivity are the most sensitive factors to the recovery degree. And, desirable tight oil production performance can be achieved with the application of the optimized bottom-hole pressure.
3D Nonlinear Analysis of Stilling Basin in Complex Fractured Dam Foundation
Authors: Meng Qingxiang , Wang Jian , Tao Zhigang , Ren Dazhong , Zhang Guangcheng , Li Xiaoshuang , Xie Liangfu 
Published: May 2022

Abstract
With the development of hydraulic engineering, more hydropower stations are built in the complex geological condition. This work proposed a case study on stilling basin in complex fractured dam foundation using 3D nonlinear analysis. A detail implementation of the numerical mesh generation from profile to solid geometry using boundary representation (B-Rep) is illustrated. Considering the main factors like self-weight, hydrodynamic pressure, and uplift pressure, the stress and deformation results of stilling basin in complex fractured foundation are obtained. According to the calculation and analysis, the design stilling basin can meet the engineering requirements of hydraulic structure. However, it is suggested to carry out the necessary foundation treatment for the sericitized slate as well as fracture plane. The study will provide valuable reference in the analysis of related engineering.
Elemental and Sr-Nd-Pb-Hf Isotope Signatures of Early Cretaceous Magmatic Rocks in the Wulian Area, Eastern Shandong: Implications for Crust-Mantle Interaction at the Edge of the Sulu Collisional Orogenic Belt
Authors: Du Qing , Meng Fanchao , Kerr Andrew C. , Chen Yong , Tian Yulu , Wu Zhiping , Zhou Yaoqi 
Published: May 2022

Abstract
We present new whole-rock geochemical, Sr-Nd-Pb isotopic, and zircon U-Pb and Hf isotopic data for Early Cretaceous magmatic rocks (trachy-andesite, pyroxene diorite, diorite porphyrite, and dolerite) in the Wulian area of Shandong, eastern North China. These data are used to constrain the mechanism of crust-mantle interaction at the edge of the Sulu orogenic belt. The belt formed by the collision of the Yangtze Craton (YC) and the North China Craton (NCC) during the Mesozoic. New zircon U-Pb dating indicates that the magmatic rocks were formed during the Early Cretaceous (123-124 Ma). These rocks are characterized by moderate contents of SiO2 (50.0-60.0 wt.%), MgO (3.3-5.6 wt.%), Cr and Ni with low Nb/U ratios (0.8-11.8), and high La/Nb (5.2-24.5) and Ba/La ratios (12.3-38.1). They are enriched in large ion lithophile elements, depleted in high field strength elements, and are characterized by high initial 87Sr/86Sr values (0.7079-0.7088) and low εNdt (-20.6 to -14.6). The samples have relatively low initial 206Pb/204Pb (16.38-17.18), 207Pb/204Pb (15.38-15.48), and 208Pb/204Pb (37.24-37.83) values. The Sr-Nd-Pb-Hf isotopic characteristics of the samples are similar to those of mafic rocks in the Sulu orogenic belt, suggesting that they might have similar sources. It is clear that the magma source of the samples involves both crustal and mantle materials and so we propose a model for crust-mantle interaction at the edge of Sulu orogenic belt. In this model, the Yangtze plate subducted deep below the northwestern NCC during the Triassic and was trapped in the lithospheric mantle. In the early Cretaceous, lithospheric extension in combination with asthenospheric upwelling resulted in partial melting of the overlying lithospheric mantle. The magmatic rocks in the Wulian area were generated by mixing between melts of both the lithospheric mantle of the NCC and the residual lower crust of the YC. This study therefore provides significant information on crust-mantle interaction at a continental subduction zone.
Effect of vaporizing cannabis rich in cannabidiol on cannabinoid levels in blood and on driving ability a randomized clinical trial
Authors: Egloff Laura , Frei Priska , Gerlach Kathrin , Mercer-Chalmers-Bender Katja , Scheurer Eva 
Published: May 2022

Abstract
Objective: To determine cannabinoid-levels in blood and driving-related ability after single (S1) and repetitive (S2) vapor inhalation of cannabis low in Δ9-tetrahydrocannabinol (THC), but high in cannabidiol (CBD). Methods: In a prospective, randomized, cross-over study at the Institute of Forensic Medicine Basel, healthy adults (NS1=27, NS2=20) vapor-inhaled two low-THC/CBD-rich products (both <1% THC), and placebo. Outcomes: i) THC- and CBD-levels in whole blood, ii) assessment of driving-related ability.Results: Among 74 participants included, 27 (mean age ± SD, 28.9 ± 12.5 years) completed S1, and 20 (25.2 ± 4.0) completed S2. THC dropped below 1.5 µg/L after 1.5 h, but was detected up to 5 h. Pairwise comparison of driving-related ability revealed no significant differences between low-THC/CBD-rich products (P1, P2) and placebo (P1 - P2: β = 0.319 [95% CI, -1.731 to 2.368], p = 0.950; P1 - placebo: β = 0.854 [95% CI, -1.329 to 3.037], p = 0.724; P2 - placebo: β = 0.535 [95% CI, -1.632 to 2.702], p = 0.879).Conclusions: Detection of THC after consumption of low-THC/CBD-rich cannabis might have legal consequences for drivers. Regarding overall driving-related ability, no significant differences were observed between interventional products.Trial Registration: German Clinical Trials Register: DRKS00018836.
Development and Application of Information Resources for Education and Teaching of Yarn History Based on 5G Network Technology
Authors: Yang Xiaoming 
Published: May 2022

Abstract
Yarn education is a crucial step in producing high-quality textile end products. Online yarn testing can reduce latency in necessary process control by providing rapid insights into yarn quality, leading to the production of superior quality yarns. This paper proposes the development and application of information resources for the education and teaching of yarn history based on fifth-generation (5G) network technologies. Initially, the yarn database is preprocessed using Grayscale transformation and image filtering methods. Secondly, yarn segmentation is implemented using a Multi-resolution Markov Random Field (MRMRF) model. The statistical and relative features are extracted using Fourier transform and two-scale attention model respectively. We propose Improved Support Vector Machine (ISVM) classification for classifying the yarn images. The 5G network is initialized and Transmission Control Protocol is used for data transfer. To enhance the performance we propose an Improved Particle Swarm Optimization (IPSO) algorithm. The performance of the suggested methodology is analyzed and compared with existing methodologies using the MATLAB simulation tool. The classification performance of the proposed algorithm indicates that the 5G framework might provide an accurate, fast, reliable, and cost-effective solution to industrial automation.
Antibacterial effect of kitchen herbs against pathogenic Multi Drug Resistant E. coli isolates from Calf Diarrhoea
Authors: Rai Saroj , Kumar M. , Jas R. , Mandal G.P. , Samanta I. , Rajendar M. , Tripura S. , Das S.K. , Mondal M. , Mandal D.K. 
Published: May 2022

Abstract
Calf diarrhoea remains the biggest challenge both in the small and large farms. Infectious diarrhoea is associated with many pathogens, E coli being one but, majority are systematically treated with antibiotics. Since antimicrobial resistance (AMR) is a growing menace, the need to find alternative prophylactic solutions using popular kitchen herbs such as Trachyspermum ammi (Carom seeds), Curcuma Longa (Turmeric) and Cinnamon (Cinnamomum sp.) extracts is been investigated against virulent form of E. coli isolated from calf diarrhoea. The virulence factors identified in these isolates were ST (32.5%), LT (20%), eaeA (15%), stx1 (2.5%) and stx2 (5%) with the occurrence of the most common serogroups as O18 (15%) followed by O111 (12.5%). Highest resistance was seen with β lactamase inhibitor (Amoxicillin/Clavalinic acid) followed by β lactams (Ampicillin, Cefuroxime and Cefepime). Antibacterial effect of cinnamon (methanol) and carom seed (ethanol) extracts was found to be highly sensitive at higher concentration of the extract (500 to 250 µg/ml) while, minimum inhibitory concentration (MIC) of turmeric was significantly higher (P&lt;0.05) followed by cinnamon. Turmeric, cinnamon and carom had the potency of inhibiting the pathogenic E coli which maybe suggestive of its use in calf diets as prophylaxis against diarrhoea.
Photonically Active Bowtie Nanoassemblies with Chirality Continuum
Authors: Kotov Nicholas , Kumar Prashant , Vo Thi , Cha Minjeong , Visheratina Anastasia , Kim Ji-Young , Xu Wenqian , Schwartz Jonathan , Simon Alexander , Katz Daniel , Marino Emanuele , Choi Won Jin , Chen Si , Murray Christopher , Hovden Robert , Glotzer Sharon 
Published: May 2022

Abstract
Chirality is a geometrical property described by continuous mathematical functions.1–5 However, in chemical disciplines chirality is often treated as a binary left/right characteristic of molecules rather than a continuity of chiral shapes. While being theoretically possible, a family of stable chemical structures with the same shape and progressively tunable chirality is yet unknown. Here we present such structures in the form of nanostructured microparticles with anisotropic bowtie shape and widely tunable twist angle, pitch, size, thickness, and length. The self-limited assembly of the bowties enables high synthetic reproducibility, size monodispersity, and computational predictability of their geometries for different assembly conditions.6 The bowties nanoassemblies display multiple strong circular dichroism peaks originating from absorptive and scattering phenomena. Unlike classical chiral molecules, these particles display a continuum of chirality measures2 that correlate exponentially with the spectral positions of the circular dichroism peaks. Bowtie particles with variable polarization rotation were used to print photonically active metasurfaces with spectrally tunable positive/negative polarization signatures for light detection and ranging (LIDAR) devices.
Effectiveness of an Activity Package to Enhance Midwifery Clinical Leadership among Nursing Students: A Quasi-Experimental Study
Authors: Chooha Umasawan , Chotwattanakulchai Nadsuda , Duangsamran Duangduean , Sirisome Jirawun 
Published: May 2022

Abstract
Background: Current health crises have effects on maternal and child nursing. The healthcare system needs midwifery with good clinical leadership. The safety of mothers and infants is dependent on decisions made by midwifery to provide help if unexpected events occur. This quasi-experimental research was aimed at studying the effectiveness of an activity package for enhancing midwifery clinical leadership on nursing students.Methods: The quasi-experimental research with a one–group pretest–posttest design was conducted among Thirty undergraduate nursing students in fourth years were selected by randomly sampling and were allocated to one group. An activity package based on leadership skill approach theory. Data were collected before, immediately after, and six weeks after the intervention using “midwifery clinical leadership knowledge” “midwifery clinical leadership skills” and “satisfaction” Questionnaires. Data were analyzed using SPSS 22; Descriptive statistics, Paired t-test, and Analysis of Variances with Repeated Measures were used to analyze the data. Results: The mean score of midwifery clinical leadership knowledge in participants before the intervention was 9.56±1.52 that increased to 16.00±1.11 after the intervention (p<.001), midwifery clinical leadership skills before, immediately after, and 6 weeks after training, it was statistically significantly higher than before training at .05 and the trainees had maximum satisfaction with the training packageConclusion: Midwifery clinical leadership among nursing students increased in every area after training. Therefore, the promotion of midwifery clinical leadership among nursing students is essential. Supporting course activities can develop learning processes in nursing students while enhancing professional midwifery skills.
Flood risk identification using multicriteria spatial analysis. Case study: Gilort River between Bălcești and Bolbocești.
Authors: Giurea Alexandru-Andrei , COMĂNESCU Laura , DOBRE Robert , NEDELEA Alexandru , MIREA Ioana-Alexandra 
Published: May 2022

Abstract
Floods are the most widespread hazard globally and have a significant impact on local communities in terms of material and loss of life. Flood risk analysis is a complex process that needs to be addressed both physically and socially. The study provides a method for identifying the risk using Goegraphical Informational Systems techniques. Each indicator taken into account was analyzed, standardized and weighted to obtain the final results. The risk values have been divided into five classes: very low, low, medium, high and very high. The case study was represented by the River Gilort (a tributary to Jiu River), in a hilly area (Getic Sub Carpathians), between Bălcești and Bolbocești). Thus, the last two risk classes listed characterize the localities with the highest population density and which are situated near the river proximity. The results can also be used by the competent local authorities to effectively manage flood risk.