bluuebunny/crossref_metadata_2025_split huggingface dataset:
Model for establishing a new liver transplantation center through mentorship from a university with transplantation expertise
Authors: Pinheiro Rafael Soares , Andraus Wellington , Romeiro Fernando Gomes , de Martino Rodrigo Bronze , Ducatti Liliana , Arantes Rubens Macedo , Pelafsky Leonardo , Hasimoto Claudia Nishida , Yamashiro Fabio da Silva , Nacif Lucas Souto , Haddad Luciana Bertocco de Paiva , Santos Vinicius Rocha , Waisberg Daniel Reis , Vane Matheus Fachini , Rocha-Filho Joel Avancini , de Oliveira Walmar Kerche , Carneiro-D’Albuquerque Luiz Augusto 
Published: March 2022

Background
Setting up new liver transplant (LT) centers is essential for countries with organ shortages. However, good outcomes require experience, because LT learning depends on a high number of surgeries. This study aims to describe how a new center was set up from a partnership between the new center and an experienced one. The step-by-step preparation process, the time needed and the results of the new center are depicted.

Material and methods
The mentoring process lasted 40 months, in which half of the 52 patients included on the transplant list received LT. After the mentorship, a 22-month period was also analyzed, in which 46 new patients were added to the waiting list and nine were operated on.

Results
The 30-day survival rates during (92.3%) and after (66.7%) the partnership were similar to the other LT centers in the same region, as well as the rates of longer periods. The waiting time on the LT list, the characteristics of the donors and the ischemia times did not differ during or after the mentorship.

Conclusion
The partnership between universities is a suitable way to set up LT centers, achieving good results for the institutions and the patients involved.
Canagliflozin-associated severe hyponatremia: a rare and potentially adverse effect?
Authors: Dhanasekaran Maheswaran , Narayanan Siddharth , Mastoris Ioannis , Mehta Suchita 
Published: March 2022

Summary
Sodium-glucose cotransporter-2 inhibitors (SGLT2i) induce osmotic diuresis by inhibiting the proximal renal tubular reabsorption of the filtered glucose load, which in turn can occasionally lead to severe dehydration and hypotension amidst other adverse effects. We present a case of a 49-year-old man with type 2 diabetes mellitus (T2D) on canagliflozin, a SGLT2i. The patient was brought to the emergency room following a motor vehicle accident. He was confused and had an altered mental status. His blood alcohol and urine toxicology screens were negative. Initial investigations revealed that he had severe hyponatremia with euglycemic ketoacidosis. The adverse condition was reversed with close monitoring and timely management, and the patient was eventually discharged. This is the first report to suggest hyponatremia as a potentially serious adverse effect following SGLT2i therapy. Its impact on the renal tubule handling of sodium and water is not yet well characterized. While further studies are warranted to understand better the pathophysiological mechanisms associated with SGLT2i-induced adverse effects, timely dose reduction or perhaps even its temporary discontinuation may be recommended to prevent complications.

Learning points

Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are usually well-tolerated, but some serious adverse effects have been documented.

Our case report suggests hyponatremia as a potential, rare side effect of SGLT2i and makes physicians aware of the occurrence of such life-threatening but preventable complications.

Timely and close monitoring of the patient, with temporary discontinuation of this drug, may be recommended towards effective management.

Studies demonstrating a comprehensive understanding of SGLT2i-related electrolyte derangements are warranted.
Tecnologías de caza en la localidad arqueológica Laguna Azul de la meseta de Somuncurá: estudios experimentales y traceológicos
Authors: Lynch Virginia , Salgado Emmanuel , Vargas Gariglio Jorgelina , Daniele Gonzalo , Hermo Darío Omar 
Published: March 2022

La localidad arqueológica Laguna Azul (LA) registra numerosas estructuras de piedra con morfologías variables y fechados del Holoceno Tardío (ca. 1906 ± 26 BP y 1756 ± 28 años AP). La presencia de gran cantidad de puntas de proyectil en las mismas con diferentes etapas de manufactura y diseño, nos ha llevado a generar interrogantes en cuantos a los rastros de uso y descarte de estos elementos.
En este trabajo se presenta el protocolo experimental y los resultados alcanzados mediante la utilización de réplicas de cabezales líticos, teniendo en consideración los diseños identificados en LA y uso de materias primas locales. Esto se llevó a cabo para incrementar el conocimiento acerca de estos diseños y su resistencia al impacto; junto con el análisis y registro de rastros generados por manufactura, uso y descarte de este tipo de tecnología a nivel microscópico.
El desarrollo de ésta primera etapa experimental permitió generar bases interpretativas de variables y verificación de hipótesis, al igual que la observación de la performance de diversos elementos componentes en una situación controlada.
Mobilization Safety of Critically Ill Children
Authors: LaRosa Jessica M. , Nelliot Archana , Zaidi Munfarid , Vaidya Dhananjay , Awojoodu Ronke , Kudchadkar Sapna R. 
Published: March 2022

BACKGROUND
Children in PICUs experience negative sequelae of immobility; however, interprofessional staff concerns about safety are a barrier to early mobilization. Our objective was to determine the safety profile of early mobilization in PICU patients.

METHODS
We conducted a secondary analysis of a 2-day study focused on physical rehabilitation in 82 PICUs in 65 US hospitals. Patients who had ≥72-hour admissions and participated in a mobility event were included. The primary outcome was occurrence of a potential safety event during mobilizations.

RESULTS
On 1433 patient days, 4658 mobility events occurred with a potential safety event rate of 4% (95% confidence interval [CI], 3.6%–4.7%). Most potential safety events were transient physiologic changes. Medical equipment dislodgement was rare (0.3%), with no falls or cardiac arrests. Potential safety event rates did not differ by patient age or sex. Patients had higher potential safety event rates if they screened positive for delirium (7.8%; adjusted odds ratio, 5.86; 95% CI, 2.17–15.86) or were not screened for delirium (4.7%; adjusted odds ratio, 3.98; 95% CI, 1.82–8.72). There were no differences in potential safety event rates by PICU intervention, including respiratory support or vasoactive support.

CONCLUSIONS
Early PICU mobilization has a strong safety profile and medical equipment dislodgement is rare. No PICU interventions were associated with increased potential safety event rates. Delirium is associated with higher potential safety event rates. These findings highlight the need to improve provider education and confidence in mobilizing critically ill children.
Biofortification with copper nanoparticles (Nps Cu) and its effect on the physical and nutraceutical quality of hydroponic melon fruits
Authors: FORTIS HERNÁNDEZ Manuel , ORTIZ LOPEZ Jaime , PRECIADO RANGEL Pablo , TREJO VALENCIA Radames , LAGUNES FORTIZ Erika , ANDRADE-SIFUENTES Alfonso , RUEDA PUENTE Edgar O. 
Published: March 2022

Currently, the use of nanoparticles is having an impact on agricultural production. There is evidence that copper nanoparticles have a strong impact on the growth and development of different crops. Biofortification specifically with (NPs Cu) improves the nutritional quality of food and its consumption has a positive influence on the health of humanity. The objective of this study consisted in evaluating the foliar application of copper nanoparticles (NPs Cu), on the weight of the fruit, nutraceutical quality and concentration of copper in melon fruit pulp. The treatments consisted of five doses of Cu NPs: 0, 1.8, 3.6, 5.4, 7.2 and 9.0 mg L -1 sprinkled foliarly. The variables evaluated were fruit weight, polar and equatorial diameter, firmness, total soluble solids, bioactive compounds and copper content in melon pulp. The results obtained indicated that the foliar application of NPs Cu, improved the physical and nutraceutical quality and the concentration of Cu in melon fruits. The highest weight and the best diameters of the fruit were obtained with the highest concentrations of NPs Cu (7.2 and 9.0 mg L-1). The concentration of 3.6 mg L-1 Cu NPs presented the highest antioxidant capacity with a value of 117,713 mg equiv. Trolox * 100 mg -1 PF, and higher content of phenols with 243.68 mg ac. gallic / 100 g FP, exceeding the concentration of 1.8 mg L -1 by 39% and the control treatment by 48%. The 3.6 and 5.4 mg L-1 treatments obtained the highest amount of flavonoids with values ​​of 149.903 and 148.29 mg QE / 100 g -1 FP, respectively. Regarding the copper concentration in the melon fruit pulp, the 9.0 mg L-1 treatment presented the highest concentration with a value of 5.39 mg kg -1 PS; The results show that, statistically, there is a correlation between the copper nanoparticles and the phytochemical variables in melon fruits. It is concluded that the use of Cu NPs can be an alternative to enrich melon fruits, and could help to solve the copper deficiency in the diet of the population.
Floristic diversity of climbing plants in tropical forests of Similipal Biosphere Reserve, Odisha, India
Authors: ROUT Debidutta , MOHANTA Manas R. , SAHU Sudam C. 
Published: March 2022

Climbers influence the diversity and composition of forest ecosystem immensely. We have investigated the floristic composition of climbing plants in tropical forests of Similipal Biosphere Reserve (SBR), Odisha, India. A total of 120 climber plant species belonging to 74 genera and 33 families were documented in all forests. Among families, the most speciose families were Fabaceae (25 species) and Convolvulaceae (22 species) followed by Cucurbitaceae (11 species), Vitaceae (8 species), Dioscoreaceae (7 species) etc. Similarly, dominant genera were Ipomoea possessing the highest number of species i.e., 9 species followed by Dioscorea (7 species), Vigna (6 species) and Cissus (4 species) etc. There was a remarkable difference noted in the structure and climbing mechanism of different climbers. The climbing plants diversity of SBR not only contributing to the overall forest biodiversity significantly but also maintain the ecological balance of the whole ecosystem. Climbers are the major resource of economic value in and around the biosphere reserve and thus their use and sustainable management must be given principal attention.
The Body-Organism Difference as a Bridge between Particular Sciences and Philosophy in Understanding Human Person
Authors: Pańpuch Zbigniew 
Published: March 2022

The article copes with a plurality of sciences in general and focuses in the human-related sciences, which present different cognitive results. There is difficult to co-ordinate them because of the difference in methods, aims and formal objects of sciences, whereas the material object of various sciences - the real man exists as the only subject, with a definite and clearly determined substance. In a consequence, they produce different concepts of man. Is it possible to co-ordinate or to reconcile these various information about human being, especially these from particular sciences with the philosophical anthropology?
A general understanding of the biological organism is of this kind that it is an object of science, but the notion of organism has been present in philosophy quite a long time—from the ancient times. Thus, an outline of the problem appears, namely the distinction between the organism, as an object of possible experience (fundamentally internal, but also external) and the body in the metaphysical sense, as an sub-ontic element of the human being. From the metaphysical point of view it seems (and that is my proposition or may be only a point mentioned anywhere by some authors, which I would like especially stress), that this whole—consisting of its organic parts, all unified in systemic reciprocal dependencies and various relations—is only accidental to human substance. This human substance—is a person. This specific “set of accidentals” constituting the human organism is subordinated (subjected) to the substance and exists in it and by it.
Such an understanding of the organism and more precisely described distinction between it and the body can determine the field of interest of philosophy and other sciences, and simultaneously create a bridge between them. Human organism could be a good object of various research in the field of particular sciences. But the scientists should not forget about metaphysic and existential background of the human organism. From the other hand, the philosophers looking for the necessary causes of the human being have to take in consideration this necessary and specific set of accidentals (a human organism) and the particular knowledge of it provided by the scientists.
Migrazioni, Globalizzazione, diritti umani e salute
Authors: Martino Ardigò , Bontempo Scavo Sara 
Published: March 2022

I processi in atto mondialmente come fattori specifici di questa fase della globalizzazione rappresentano insieme ai grandi cambiamenti epidemiologici e demografici rappresentano una cornice imprescindibile per l’analisi della salute dei migranti. Questo articolo si propone di analizzare il campo specifico della salute dei migranti attraverso un approccio interdisciplinare. I processi salute malattia in cui i migranti sono coinvolti vengono analizzati in chiave critica rispetto alla produzione di conoscenza in campo sanitario rilevando allo stesso tempo le opportunità in termini di costruzione di una cornice di ricerca e formazione e pratiche interdisciplinare, e le ricadute positive in termini di organizzazione dei servizi alla persona e clinici.
Projeto de Extensão Corpo em Movimento: experiências e percepções
Authors: VALE MARLIETE PEREIRA DO VALE PEREIRA 
Published: March 2022

ResumoObjetivo: Analisar as contribuições e benefícios do Projeto de Extensão Corpo em Movimento: Atividade Física e Saúde Mental da Universidade Estadual Vale do Acaraú, contribuindo para a melhoria da qualidade de vida física e mental da comunidade universitária. Metodologia: O trabalho realizou uma abordagem de cunho qualitativo, a partir de um questionário semiestruturado, para a avaliação dos benefícios na melhoria da qualidade de vida da comunidade universitária participante do referido projeto, no período de março de 2018 a fevereiro de 2019. Resultados: Os dados obtidos foram sistematizados considerando as respostas dadas por 61 participantes, desdobrando-se em duas temáticas principais: 1) Contribuições do projeto para a saúde física e mental; 2) Os benefícios das atividades do projeto para os participantes. Cada temática foi contemplada com seis categorias de análise de acordo com as falas dos participantes. Os participantes da pesquisa foram unânimes em afirmar uma série de benefícios do projeto de extensão, proporcionando-lhes melhor qualidade de vida. Os benefícios mais citados pelos participantes foram: Maior Interação Social: 67,21%; Redução do Stress: 50,82%; Melhor condicionamento Físico: 47,54%; Propicia Atividade Física: 37,70%; Melhor Saúde: 32,79%; Saúde Mental: 29,51%; Maior Relaxamento: 21,31%; Mais Lazer: 18,03%; Bem-Estar: 14,75%; Melhora o humor: 14,75%. Considerações finais: Nesta perspectiva acredita-se que um dos caminhos para uma vida saudável é o envolvimento regular em alguma atividade física, tendo como objetivo a melhoria de seu estado de saúde física e mental.
Liga interdisciplinar em saúde mental: trilhando caminhos para a promoção em saúde
Authors: Oliveira Eliany Nazaré , Viana Lorenna Saraiva , Oliveira Lycelia da Silva , Aragão Heliandra Linhares , Sousa Filho Altenório Lopes , Sobrinho Natasha Vasconcelos , Ávila Alyce Marina Almeida 
Published: March 2022

DEVAGAR SE VAI LONGE: A EXPERIÊNCIA DA LIGA INTERDISCIPLINAR EM SAÚDE MENTAL MENTAL HEALTH INTERDISCIPLINARY LEAGUE: PAVING WAYS FOR HEALTH PROMOTIONObjetivo: Relatar a experiência da Liga Interdisciplinar em Saúde Mental (LISAM) em seus diversos contextos de atuação. Métodos: Trata-se de um estudo descritivo do tipo relato de experiência. Resultados: A LISAM, vinculada a Universidade Estadual Vale do Acaraú (UVA), no município de Sobral-Ceará, desenvolve atividades de ensino, pesquisa e extensão, desde sua criação, em 2017. As atividades de ensino envolvem aulas, seminários, análise e discussão de textos; apresentações de casos clínicos e realização de eventos científicos. Os temas desenvolvidos durante cada semestre são identificados nas oficinas de planejamento da liga. No âmbito da pesquisa, a LISAM possui três em desenvolvimento: Risco de Suicídio em usuários de substâncias psicoativas; Análise do consumo de drogas no contexto escolar e Qualidade de vida e saúde mental de estudantes universitários. No que concerne à extensão, a LISAM desenvolve ações em diversos dispositivos tendo como foco o fortalecimento das estratégias promotoras de saúde mental, de modo a atuar junto às vulnerabilidades locais. Além disso, propõe a construção de práticas interdisciplinares, orientadas pelo princípio da universalidade, equidade e que visa envolver os estudantes em atividades no âmbito da saúde mental da população, propiciando a integração e articulação de ações de promoção à saúde nesse âmbito. Considerações Finais: Compreende-se, portanto que a LISAM tem se constituído como um espaço fértil de aprendizagem, ensino, pesquisa e extensão, contribuindo para a formação de profissionais, éticos, reflexivos e sensíveis não apenas para as necessidades da comunidade, mas também para o cuidado de sua própria saúde física e mental.
A INCLUSÃO DA PESSOA COM DEFICIÊNCIA NO ENSINO SUPERIOR: TRAJETÓRIA DE IMPLANTAÇÃO DA COMISSÃO PERMANENTE UFRJ-MACAÉ ACESSÍVEL E INCLUSIVA
Authors: Capelli Jane de Carlos Santana , Souza Inês Leoneza de , Vieira Uliana Pontes , Alvarez Adriana Bispo , Paiva Raquel Silva de 
Published: March 2022

Objetivo: apresentar as experiências do processo de implantação até as ações recentes da Comissão Permanente UFRJ-MACAÉ Acessível e Inclusiva, da UFRJ-Campus Macaé Professor Aloísio Teixeira. Métodos: O estudo apresenta um relato de experiências vividas por membros da CPAI, no período entre o segundo semestre de 2016 e 2019. Para a estruturação deste relato, foram reunidas as memórias dos encontros, atas de reuniões da CPAI, publicações de matérias referentes a CPAI tanto na mídia impressa como digital. Resultados: Foram identificados quatro aspetos relevantes: História da consolidação das instâncias voltadas às pessoas com deficiência na UFRJ; Implantação da CPAI; Entrada dos estudantes com deficiência na UFRJ-Campus Macaé; Ações da CPAI. Considerações finais: A CPAI tem realizado ações que propiciam um frequente diálogo sobre a acessibilidade e inclusão de estudantes com deficiência, sendo relevante para a atenção a estes no âmbito do ensino superior, por muitas vezes acessível apenas para uma parcela da população com deficiência.
La libre évolution, un concept aux multiples facettes
Authors: Barthod Christian , Dupouey Jean-Luc , Larrère Raphaël , Sarrazin François 
Published: March 2022

Après une brève mise au point terminologique et sémantique sur le concept de libre évolution, proche de celui de naturalité, les éditeurs de ce numéro thématique en présentent les enjeux forestiers, la spécificité européenne et les attentes variées et parfois contradictoires des divers acteurs, gestionnaires en charge de la forêt et de l’environnement, scientifiques, associations ou grand public. L’objectif de ce numéro est de leur fournir matière à une réflexion la plus ouverte possible sur un sujet encore en évolution rapide et objet de débats parfois passionnés. Sont ensuite introduits les 18 articles qui abordent, sans viser à l’exhaustivité, diverses facettes de la libre évolution : philosophique, historique, scientifique, technique, politique, culturelle, dans un cadre principalement métropolitain avec quelques éclairages d’autres pays européens. L’émergence, récente à l’échelle du temps des forêts, de la prise en compte de la biodiversité dans la gestion rend ces connaissances nécessaires à l’honnête homme forestier.
Travaux actuels d'inventaire des forêts à forte naturalité à l'échelle nationale et européenne
Authors: Benest Fabienne , Carruthers-Jones Jonathan , Guetté Adrien 
Published: March 2022

Divers travaux menés à différentes échelles concernent la distribution des forêts anciennes et matures, mais il n’existe pas à ce jour de cartographie complète au niveau national. Au niveau européen, le récent rapport du Joint Research Centre de l’Union européenne donne quelques éléments. Au niveau national, la cartographie des forêts anciennes (continuité de l’état boisé) progresse, et parallèlement, le projet CARTNAT envisage le niveau de naturalité toutes occupations du sol confondues. Une récente étude de l’INRAE a permis de modéliser la distribution des forêts selon leur date de dernière exploitation. Les réserves biologiques intégrales créées en forêt publique, maintenues en libre évolution sur 27 000 ha en métropole, ont fait l’objet en 2020 d’un bilan complet de leur contenu en termes d’habitats forestiers. En Nouvelle-Aquitaine, une méthode croisant diverses données géographiques et d’inventaires a permis de situer des zones à fort potentiel de naturalité au sein des forêts anciennes. Les forêts récentes, férales, liées à la recolonisation spontanée par une végétation forestière de zones en déprise font maintenant l’objet d’un suivi spécifique dans les protocoles de l’Inventaire forestier national.
Conservation/préservation de la nature « sauvage » : une histoire des savoirs, des imaginaires et des idéologies (XIXe siècle et première partie du XXe siècle)
Authors: Chalvet Martine 
Published: March 2022

Les idées de retour à la nature, de libre évolution, de naturalité connaissent actuellement un certain succès. Mais quelle est l’histoire de ces courants de pensées et de leurs applications concrètes aux États Unis d’Amérique mais aussi dans les États européens et leurs colonies ? Du XIXe siècle à la première moitié du XXe siècle, cet article vise à comprendre comment des courants spécifiques de préservation de la nature se dégagent des autres tendances des mouvements de protection de la nature. À travers l’histoire des savoirs écologiques, mais aussi des dimensions culturelles, identitaires et idéologiques de la nature, nous chercherons à comprendre la circulation des connaissances, des pratiques et des modèles à l’échelle transnationale mais aussi à proposer une histoire nationale des imaginaires, des symboliques et des idéologies de la nature.