bluuebunny/crossref_metadata_2025_split huggingface dataset:
Proton gradient mediates hemolymph trehalose influx into aphid bacteriocytes
Authors: Iwata Mana , Yoshinaga Mayu , Mizutani Kosuke , Kikawada Takahiro , Kikuta Shingo 
Published: October 2022

AbstractAphids harbor proteobacterial endosymbionts such as Buchnera aphidicola housed in specialized bacteriocytes derived from host cells. The endosymbiont Buchnera supplies essential amino acids such as arginine to the host cells and, in turn, obtains sugars needed for its survival from the hemolymph. The mechanism of sugar supply in aphid bacteriocytes has been rarely studied. It also remains unclear how Buchnera acquires its carbon source. The hemolymph sugars in Acyrthosiphon pisum are composed of the disaccharide trehalose containing two glucose molecules. Here, we report for the first time that trehalose is transported and used as a potential carbon source by Buchnera across the bacteriocyte plasma membrane via trehalose transporters. The current study characterized the bacteriocyte trehalose transporter Ap_ST11 (LOC100159441) using the Xenopus oocyte expression system. The Ap_ST11 transporter was found to be proton‐dependent with a Km value ≥700 mM. We re‐examined the hemolymph trehalose at 217.8 mM using a fluorescent trehalose sensor. The bacteriocytes did not obtain trehalose by facilitated diffusion along the gradient across cellular membranes. These findings suggest that trehalose influx into the bacteriocytes depends on the extracellular proton‐driven secondary electrochemical transporter.
Electrocatalytic Carbon Dioxide Reduction to Ethylene over Copper‐based Catalytic Systems
Authors: Yang Yisen , Tan Zhonghao , Zhang Jianling 
Published: October 2022

AbstractThe electrocatalytic carbon dioxide (CO2) conversion to ethylene (C2H4) has attracted significant attention in recent years. Copper‐based catalytic systems have been proven to be the most efficient for producing C2H4from electrocatalytic CO2reduction reaction. In this review, we present the recent progress on the electrocatalytic CO2reduction to C2H4over copper‐based catalytic systems, mainly focusing on reaction mechanism, design of catalysts and influences of electrolyte, CO2supplement and electrolyzer on activity, selectivity and stability.
DNA methylation profile of lip tissue from congenital nonsyndromic cleft lip and palate patients by whole‐genome bisulfite sequencing
Authors: Zhang Bowen , Zhang Youmeng , Wu Siyi , Ma Duan , Ma Jing 
Published: October 2022

AbstractCongenital nonsyndromic cleft lip and palate (NSCLP) is one of the most common malformations worldwide. DNA methylation has been implicated in many diseases. However, its involvement in lip tissue from NSCLP is not well understood. This study aimed to investigate the role of dysregulated DNA methylation in NSCLP. DNA methylation profile was determined in eight injured and five self‐normal lip tissue samples from children with NSCLP by whole‐genome bisulfite sequencing. A total of 2,711 differentially methylated regions (DMRs), corresponding to 1,231 genes were identified. Given the important role of promoter methylation in regulating gene expression, the promoter DMR‐related genes were considered. Bioinformatics analysis demonstrated that some of them showed potential associations with NSCLP. Therefore, the well‐known NSCLP susceptibility gene, GLI family zinc finger 2 (GLI2) with an unknown role in its DNA methylation in NSCLP, was selected for further analysis. The promoter hypomethylation and higher mRNA expression level of GLI2 were observed in injured lip tissues by verification in additional samples. Moreover, dual luciferase reporter assay indicated that promoter hypermethylation of GLI2 inhibited its transcription. Overall, this study suggested that abnormal DNA methylation in lip tissue may be correlated with the pathogenesis of congenital NSCLP.
Thermally stable red luminescence from Eu3+‐activated telluro zinc phosphate glass under near‐ultraviolet light excitation for photonic applications
Authors: Vikas  , Jayasimhadri Mula 
Published: October 2022

AbstractTelluro zinc phosphate (TZP) glasses doped with different concentrations of Eu3+ ions were prepared and their physical, structural, and luminescence properties were studied in detail to reveal the utility of the as‐prepared glass for white light‐emitting diode (w‐LED) applications. The broad hump in the diffraction pattern specified the amorphous behaviour of the TZP glass. The various vibrational shoulder linkages were characterized using the Fourier transform infrared (FT‐IR) spectroscopy. The optical absorption spectrum was measured in the ultraviolet (UV)–visible (Vis) light region for the Eu3+‐doped TZP (TZPE) glass and the optical band gap was found to be 3.12 eV. Eu3+‐doped TZP glasses showed several emission peaks in the visible region including an intense red emission peak due to the 5D0→7F2 transition under an excitation wavelength of λex = 393 nm, which was matched with the emitting wavelength of the near‐UV LED chip. Commission Internationale de I'Eclairage (CIE) chromaticity coordinates were situated in the red region and nearly matched with the coordinates of the commercial red phosphor (Y2O3S:Eu3+). The decay profile of the TZPE50 glass exhibited a single exponential fit with a decay time (
of 1.76 ms. Temperature‐dependent photoluminescence (TDPL) studies demonstrate that the as‐prepared glass consist of excellent thermal stability. The detailed analysis and results confirmed that the red‐emitting TZPE glasses were potential candidates for white‐LED and other photonic applications.
Achieving tolerance modifies cancer susceptibility profiles in liver transplant recipients
Authors: Bhat Mamatha , Pasini Elisa , Patel Preya , Yu Jeffrey , Baciu Cristina , Kurian Sunil M. , Levitsky Josh 
Published: October 2022

AbstractLong‐term survival of transplant recipients is significantly impacted by malignancy. We aimed to determine whether calcineurin inhibitor (CNI)‐treated recipients converted to and weaned off molecular target of rapamycin inhibitor (mTOR‐I) therapy have favorable changes in their molecular profiles in regard to malignancy risk. We performed gene expression profiling from liver biopsy and blood (PBMC) specimens followed by network analysis of key dysregulated genes, associated diseases and disorders, molecular and cellular functions using IPA software. Twenty non‐immune, non‐viremic patients were included, and 8 of them achieved tolerance. Two comparisons were performed: (1) tolerance time point vs tacrolimus monotherapy and (2) tolerance time point vs sirolimus monotherapy. Upon achieving tolerance, IPA predicted significant activation of DNA damage response (p = 5.40e‐04) and inhibition of DNA replication (p = 7.56e‐03). Conversion from sirolimus to tolerance showed decrease in HCC (p = 1.30e‐02), hepatic steatosis (p = 5.60e‐02) and liver fibrosis (p = 2.91e‐02) associated genes. In conclusion, this longitudinal study of patients eventually achieving tolerance reveals an evolving molecular profile associated with decreased cancer risk and improved hepatic steatosis and liver fibrosis. This provides a biological rationale for attempting conversion to mTOR‐I therapy and tolerance following liver transplantation particularly in patients at higher risk of cancer incidence and progression post‐transplant.
Navigating dual roles: Governance of statewide community college membership associations
Authors: Galizio Larry 
Published: October 2022

AbstractStatewide membership associations are comprised of trustees and/or district chancellors or college presidents (CEOs) whose primary professional responsibility is the governance and administration of local districts and colleges. The majority of these statewide community college membership associations are nonprofit entities—typically incorporated as 501(c)3 and/or 501(c)6's—and their missions characteristically include state and federal advocacy, professional and policy development, research and district support services, and the promotion of the state's community colleges to the multiple constituencies of decision‐makers, policy influencers, traditional, and social media communication platforms. The Community College League of California provides a case example of the work occurring in membership associations. Governance challenges are reviewed, and questions are posed regarding future directions.
Uncommon governance
Authors: Phelan Daniel J. 
Published: October 2022

AbstractMultiple direct observations suggest that community college board governance exists today, very much as it has for many decades, often encumbered by outmoded, unchecked, ineffectual practices, and absent clarity of purpose. The absence of a routine assessment of a board's own governance style and efficacy foretells a future inability for meaningful impact and quantum gains in the service of those the college was designed to serve. This chapter challenges board members to lean into the necessary work of governing by thoughtfully considering their current governance model and associated practices, relative to what could be greater levels of board effectiveness. A number of tools and alternatives are offered in the chapter to assist boards in this work, including the introduction of a governance hierarchy to provide an aspirational context for improved board effectiveness, as well as a new concept of Covenant Governance, and the benefits of a Policy Governance Model.
Oxidative Desulfurization Using MoO3 as Recyclable and Efficient Nanocatalyst
Authors: Sales Rita N. , Nunes Carla D. 
Published: October 2022

AbstractGathering clean energy from fuel feedstocks is of paramount significance in environmental science. In this area, desulfurization provides a valuable contribution by eliminating sulfur compounds from fuel feedstocks to ensure they can be used without emission of toxic sulfur oxides. MoO3 nanoparticles have been hydrothermally synthesized and used as efficient catalyst in the oxidative desulfurization (ODS) of methylphenyl and diphenyl sulfide using TBHP or H2O2 as oxidant. The catalyst showed an enhancement in the ODS process of the two substrates revealing influence on the reaction rate and product selectivity. Temperature and solvent influenced the conversion for the desired product as well. The activity of the catalyst was stable for at least 3 continuous catalytic cycles. Catalytic performance of MoO3 nanomaterial was comparable or better than other catalysts reported in the literature in terms of the sulfoxide or sulfone yield.
Oxidative N‐Heterocyclic Carbene Catalysis
Authors: De Risi Carmela , Brandolese Arianna , Di Carmine Graziano , Ragno Daniele , Massi Alessandro , Bortolini Olga 
Published: October 2022

AbstractN‐Heterocyclic carbene (NHC) catalysis is a by now consolidated organocatalytic platform for a number of synthetic (asymmetric) transformations via diverse reaction modes/intermediates. In addition to the typicalumpolungprocesses involving acyl anion/homoenolate equivalent species, implementation of protocols under oxidative conditions greatly expands the possibilities of this methodology. Oxidative NHC‐catalysis allows for oxidative and oxygenative transformations through specific manipulations of Breslow‐type species depending upon the oxidant used (external oxidant or O2/air), the derived NHC‐bound intermediates paving the way to non‐umpolungprocesses through activation of carbon atoms and heteroatoms. This review is intended to update the state of the art in oxidative NHC‐catalyzed reactions that appeared in the literature from 2014 to present, with a strong focus to crucial intermediates and their mechanistic implications.
Nickel‐Catalyzed Direct Arylation Polymerization for the Synthesis of Thiophene‐Based Cross‐linked Polymers
Authors: Mohr Yorck , Ranscht Alisa , Alves‐Favaro Marcelo , Alessandra Quadrelli Elsje , M. Wisser Florian , Canivet Jérôme 
Published: October 2022

AbstractAn earth‐abundant nickel(II) bipyridine catalyst, combined with lithium hexamethyldisilazide as base, demonstrates its wide applicability in the direct arylation polymerization of di‐ and tri‐thiophene heteroaryls with poly(hetero)aryl halides. With a nickel catalyst loading of 2.5 mol%, a series of twenty highly cross‐linked organic polymers is obtained in 34 to 99 % yields. Using mixed polytopic coupling partners allows obtaining alternating and optically active thiophene‐based solids with intrinsic porosity.
Oxidation of an Internal‐Edge‐Substituted [5]Helicene‐Derived Phosphine Synchronously Enhances Circularly Polarized Luminescence
Authors: Usui Kazuteru , Narita Nozomi , Eto Ryosuke , Suzuki Seika , Yokoo Atsushi , Yamamoto Kosuke , Igawa Kazunobu , Iizuka Naoko , Mimura Yuki , Umeno Tomohiro , Matsumoto Shota , Hasegawa Masashi , Tomooka Katsuhiko , Imai Yoshitane , Karasawa Satoru 
Published: October 2022

AbstractSmall chiral organic molecules with CD properties are in high demanded due to their potential use in promising electronic and biological applications. Herein, we reveal a system in which the oxidation of a phosphino group to the corresponding phosphine oxide on the inner rim of a helicene derivative induces a CPL response. Laterally π‐extended 7,8‐dihydro[5]helicenes bearing phosphine and phosphine oxide groups on their inner helical rims (i. e., the C1 position) were synthesized, and their helical structures were unambiguously determined by X‐ray crystallography. The photophysical (UV/visible and emission) and chiroptical properties of these compounds were investigated in various solvents. Despite their structural similarities, phosphine oxide showed a significantly better CPL response than phosphine, with a high dissymmetry factor for emission (|glum|=(1.3–1.9)×10−3) that can be attributed to structural changes in the interior of the helicene helix.
Inter‐Network Charge‐Transfer Excited State Formation Within a Two‐fold Catenated Metal–Organic Framework
Authors: Nath Akashdeep , Chawla Sakshi , K. De Arijit , Deria Pravas , Mandal Sukhendu 
Published: October 2022

AbstractCharge‐transfer excited state (CTES) defines the ability to split photon energy into work producing redox equivalents suitable for photocatalysis. Here, we report inter‐net CTES formation within a two‐fold catenated crystalline metal–organic framework (MOF), constructed with two linkers, N,N′‐di(4‐pyridyl)‐1,4,5,8‐naphthalenetetracarboxydiimide (DPNDI) and 2,6‐dicarboxynaphthalene (NDC). The structural flexibility puts two complementary linkers from two nets in a proximal position to interact strongly. Supported by the electrochemical and steady‐state electronic spectroscopic data, this ground‐state interaction facilitates forming CTES that can be populated by direct excitation. We map the dynamics of the CTES which persists over a few nanoseconds and highlight the utilities of such relatively long‐lived CTES as enhanced conductivity of the MOF under light over that measured in dark and as a proof‐of‐the‐principle test, photo‐reduction of methyl viologen under white light.
Einladung zum Erfahrungsaustausch
Authors: Woppowa Ljuba 
Published: October 2022

AbstractEinen echten Erfahrungsaustausch, der mehr als Informationen bietet. Das dürfen die Teilnehmenden des 13. Jahrestreffen der Betriebsingenieure des VDI‐GVC erwarten. Es stehen wieder aktuelle Themen aus der Praxis auf dem Programm. Darunter die Betreiberpflichten und die neue TA Luft im betrieblichen Alltag sowie “BIM für BING”: Building Information Modelling – vom Modell in die Praxis. Außerdem werden zentrale Themen aus dem betrieblichen Alltag wie Inbetriebnahme, Turnaround Management sowie Remote Unterstützung und digitale Tools diskutiert.
Die Nachhaltigkeitsprinzipien sind der Kompass
Authors: Gandert Etwina 
Published: October 2022

AbstractDie Chemie kann einen entscheidenden Beitrag zur mehr Nachhaltigkeit und Ressourceneinsparung leisten. Im Interview mit CITplus erläutert Dr. Andreas Förster, Geschäftsführer der Dechema, welche Maßnahmen vonseiten der Industrie und der Gesellschaft möglich und notwendig sind. Dabei ist der Weg das Ziel, immer besser zu werden und die Nachhaltigkeitsprinzipien als Kompass einzusetzen
Effizienzpotenziale nutzen
Authors: Saulich Katja 
Published: October 2022

AbstractEinsparpotenziale lassen sich entlang des gesamten Herstellungsprozesses durch den Einsatz von Digitalisierungstechnologien identifizieren und umsetzen. Ziele können eine bessere Prozessstabilität oder vorausschauende Wartung sein.
Die Formel der grünen Batterie
Authors: Diekmann Jan 
Published: October 2022

AbstractModerne Lithium‐Ionen‐Batteriezellen elektrifizieren den Alltag. Doch wie ist es um die Nachhaltigkeit der Technologie selbst bestellt? Eine grüne Batterie ist mehr als nur der Materialmix. Sie ist vielmehr das Ergebnis aus dem Zusammenspiel der verwendeten Materialien und der Effizienz zugehöriger Herstellungsprozesse. Auch ist es eine Frage von Zelldesign und ‐chemie, die zum jeweils spezifischen Anforderungsprofil passen müssen.
Für eine nachhaltige Produktionswende
Authors: Kaufmann Tobias 
Published: October 2022

AbstractProduktion und Nachhaltigkeit – ein bislang geglaubter Widerspruch wird mit dem Vorhaben zur bedarfsorientierten Steuerung von Peripheriesystemen in der Produktion (BeStPeri). Das Projekt liefert einen ganzheitlichen Ansatz zum Prinzip der Circular‐Economy mit einer hohen übertragbarkeit aus der Galvanotechnik in die Produktionstechnik.
Convergence of bilateral auditory midbrain inputs on neurons in the auditory thalamus of chicken
Authors: Ito Tetsufumi , Ono Munenori , Ohmori Harunori 
Published: October 2022

AbstractIn the avian ascending auditory pathway, the nucleus mesencephalicus lateralis pars dorsalis (MLd; the auditory midbrain center) receives inputs from virtually all lower brainstem auditory nuclei and sends outputs bilaterally to the nucleus ovoidalis (Ov; the auditory thalamic nucleus). Axons from part of the MLd terminate in a particular domain of Ov, thereby suggesting a formation of segregated pathways point‐to‐point from lower brainstem nuclei via MLd to the thalamus. However, it has not yet been demonstrated whether any spatial clustering of thalamic neurons that receive inputs from specific domains of MLd exists. Ov neurons receive input from bilateral MLds; however, the degree of laterality has not been reported yet. In this study, we injected a recombinant avian adeno‐associated virus, a transsynaptic anterograde vector into the MLd of the chick, and analyzed the distribution of labeled postsynaptic neurons on both sides of the Ov. We found that fluorescent protein‐labeled neurons on both sides of the Ov were clustered in domains corresponding to subregions of the MLd. The laterality of projections was calculated as the ratio of neurons labeled by comparing ipsilateral to contralateral projections from the MLd, and it was 1.86 on average, thereby indicating a slight ipsilateral projection dominance. Bilateral inputs from different subdomains of the MLd converged on several single Ov neurons, thereby implying a possibility of a de novo binaural processing of the auditory information in the Ov.
Chalcogen Bonds: How to Characterize Them in Solution?
Authors: Pale Patrick , Mamane Victor 
Published: October 2022

AbstractChalcogen bonds (ChBs) occur between molecules containing Lewis acidic chalcogen substituents and Lewis bases. Recently, ChB emerged as a pivotal interaction in solution‐based applications such as anion recognition, anion transport and catalysis. However, before moving to applications, the involvement of ChB must be established in solution. In this Concept article, we provide a brief review of the currently available experimental investigations of ChB in solution.
Benzenetriimide‐Based Molecular Conductor with Antiferro‐ to Ferromagnetic Switching Induced by Structural Change of π‐stacked Array
Authors: Koyama Shohei , Horii Yoji , Sato Tetsu , Takaishi Shinya , Hoshino Norihisa , Akutagawa Tomoyuki , Iguchi Hiroaki 
Published: October 2022

AbstractThe front cover artwork is provided by Dr. Hiroaki Iguchi's group at Tohoku University. The image shows the π‐stack column of BTI‐Me‐based charge transfer complexes with electrical conductivity, and the unique magnetic property reported in the paper, where the interaction between spin switches by the structural change. Read the full text of the Research Article at 10.1002/cphc.202200322.
Carbazole‐Derivative‐Based One‐Dimensional Metal‐Organic Tube Demonstrating Stimuli‐Responsive Luminescence
Authors: Luo Xin‐Yu , Lu Yu‐Lin , Wang Zheng , Pan Mei 
Published: October 2022

AbstractAn A‐π‐D‐π‐A type carbazole‐derived organic ligand was designed and synthesized, and an intriguing one‐dimensional metal‐organic tube possessing infinite tubular superstructure was successfully constructed and characterized. Inspiringly, it displayed fascinating stimuli‐responses including room‐temperature gasochromic luminescent response for volatile organic compounds and effective fluorescent quenching for nitroaromatic explosives. In particular, the capabilities of selectively detecting 2,4,6‐trinitrophenol showed great potential as a promising fluorescent sensor.
Electrocatalytic Energy Release of Norbornadiene‐Based Molecular Solar Thermal Systems: Tuning the Electrochemical Stability by Molecular Design
Authors: Franz Evanie , Krappmann Daniel , Fromm Lukas , Luchs Tobias , Görling Andreas , Hirsch Andreas , Brummel Olaf , Libuda Jörg 
Published: October 2022

AbstractMolecular solar thermal (MOST) systems, such as the norbornadiene/quadricyclane (NBD/QC) couple, combine solar energy conversion, storage, and release in a simple one‐photon one‐molecule process. Triggering the energy release electrochemically enables high control of the process, high selectivity, and reversibility. In this work, the influence of the molecular design of the MOST couple on the electrochemically triggered back‐conversion reaction was addressed for the first time. The MOST systems phenyl‐ethyl ester‐NBD/QC (NBD1/QC1) and p‐methoxyphenyl‐ethyl ester‐NBD/QC (NBD2/QC2) were investigated by in‐situ photoelectrochemical infrared spectroscopy, voltammetry, and density functional theory modelling. For QC1, partial decomposition (40 %) was observed upon back‐conversion and along with a voltammetric peak at 0.6 Vfc, which was assigned primarily to decomposition. The back‐conversion of QC2, however, occurred without detectable side products, and the corresponding peak at 0.45 Vfc was weaker by a factor of 10. It was concluded that the electrochemical stability of a NBD/QC couple is easy tunable by simple structural changes. Furthermore, the charge input and, therefore, the current for the electrochemically triggered energy release is very low, which ensures a high overall efficiency of the MOST system.
6G‐based resource utilization framework in software defined hybrid vehicular networks
Authors: Mittal Shilpi , Bali Rasmeet Singh 
Published: October 2022

SummaryAdvanced development in technology raises a huge number of data sources that generate real time data for processing. To process such huge and complex real time data, there is a need for high processing units and more computing resources available at the nearest end, which causes high deployment cost and needs distributed data processing units at different locations. To concern this issue, we proposed a 6G‐based Resource Utilization Framework using SDN in the hybrid vehicular network (HVN). The key objective of this framework is to provide the computing vehicles as resources to complete the task efficiently. Three different technologies are combined into vehicular networks such as Vehicular Fog Computing, Vehicular Edge Computing, and Vehicular Cyber Physical System into integrated HVN. A layered architecture is used to define the data flow and control with the support of SDN and also the fast delivery of data by using 6G cellular communication in the proposed HVN. This scheme uses various algorithms to provide resources through the fast communication between vehicles in Hybrid Vehicular network. An extensive simulation is performed on the proposed scheme using the NS3 simulator. The simulation results outperform the performance of the proposed scheme in terms of various key computing parameters.