bluuebunny/crossref_metadata_2025_split huggingface dataset:
GECOK BONCEL SEBAGAI KULINER KHAS KEDUNGDALEM YANG KAYA AKAN ALBUMIN BERMANFAAT BAGI PENYEMBUHAN LUKA
Authors: Lismawati Putri , Akartono  
Published: May 2022

Perkembangan kuliner khas Kedungdalem yang beraneka ragam mulai dari makanan pokok hingga selingan. Dengan perkembangan zaman inovasi berbagai macam olahan makanan dikemas menjadi kemasan yang modern, sehingga banyak makanan tradisional yang hampir tidak dikenal khususna oleh kalangan milineal. Tujuan umum dari penelitan ini adalah untuk memperoleh informasih atau gambaran, mengenain pengetahuan kalangan milenial di desa kedungdalem mengenai pengenalan masakan khas kedungdalem.metode yang digunakan pada penelitian ini adalam menggunakan metode kualitatif. Hasil penelitian ini menunjukan bahwa sebagian besar responden memiliki pengetahuan menganai pengenalan makanan khas kedungdalem, yang terdiri dari makanan pokok dan selingan seperti berbagai varian masakan ikan boncel yaitu :boncel kuah kecap, boncel kuah balado, boncel sambal ijo dan yang paling populer adalah Gecok Boncel dan makanan selingan seperti : gayam, kembili dan sukun. Berdasarkan hasil penelitian ini diharapkan masyarakat dan kalangan milenial dapat lebih mengenal pentingnya mengajarkan dan mengenalkan masakan khas desa Kedungdalem terutama hidangan yang memiliki ciri khas tersendiri seperti Gecok Boncel dan kepada kalangan milenial dapat menjaga kelestariannya, sehingga dapat diwariskan kegenerasi selanjutnya.
Kata kunci : kaum milenial kuliner Gecok Boncel desa Kedungdalem
KONSERVASI HUTAN MANGROVE SEBAGAI PENYEIMBANG EKOSISTEM DI DESA GROGOL KABUPATEN CIREBON
Authors: Fitriya Sari Dea , Husnul Khotimah Elvinda , Charisma Dila 
Published: May 2022

Hutan mangrove merupakan sumber daya alam daerah pantai payau yang sangat potensial serta memiliki fungsi perlindungan dan pelestarian alam. Di Indonesia sendiri khususnya Kabupaten Cirebon terdapat hutan mangrove sekitar 70 hektare atau 5,4 km dari 54 km garis pantai. Adanya ekowisata mangrove di Desa Grogol, Kabupaten Cirebon yaitu Wisata Bahari Micil diharapkan menjadi salah satu usaha untuk melestarikan mangrove dan meningkatkan kepekaan masyarakat terhadap kondisi lingkungan sekitar. Metode pengabdian ini dilakukan dengan menganalisis situasi masyarakat desa Grogol, kemudian mengidentifikasi permasalahan yang timbul di masyarakat yang berkaitan dengan kegiatan konservasi mangrove dan melakukan pendekatan sosial. Pendekatan sosial pada kegiatan ini tidak hanya dilakukan tim pengusung program tetapi dilakukan kolaborasi dengan berbagai pihak seperti pemuda pemudi Karang Taruna Desa Grogol dan Pengelola mangrove. Dengan adanya kolaborasi dari berbagai pihak diharapkan kesadaran masyarakat semakin meningkat terhadap kelestarian hutan mangrove.
Kata Kunci : Ekowisata, konservasi, mangrove.
SITOTOKSISITAS EKSTRAK ETANOL DAN FRAKSI-FRAKSI DAUN PEPAYA (Carica papaya L.) TERHADAP SEL KANKER PROSTAT DU 145 DENGAN METODE MTT ASSAY
Authors: Hesti Renggana  , Asman Sadino  , Risa Susanti  , Rahmi  , Sujana Dani 
Published: May 2022

Kanker prostat merupakan merupakan kanker yang paling umum diderita oleh pria selama 2016, kasus baru pada penderita kanker prostat sudah diperkirakan sebanyak 180.890 dan kasus kematian 26.120 kasus. Terapi yang sering digunakan pada penderita kanker prostat ini salah satunya adalah kemoterapi. Kemoterapi dapat menyebabkan senyawa antikanker tidak sensitif, karena terjadi resistensi sel kanker. Maka dari itu, diperlukan pula metode alternatif pengobatan tradisional atau herbal. Dalam terapi kanker, penggunan tanaman herbal dinilai memiliki efek samping yang lebih kecil dibandingkan dengan terapi menggunakan obat-obat kimia. Daun pepaya (Carica papaya L.) merupakan salah satu tumbuhan yang telah diteliti memiliki aktivitas sitotoksik MiaPaca-2 dan ASPC-1. Dalam penelitian ini, dilakukan uji sitotoksisitas ekstrak etanol dan fraksi-fraksi daun pepaya (Carica papaya L.) terhadap sel kanker DU 145 untuk mengetahui aktivitas antikanker dengan menggunakan metode MTT Assay. Hasil uji sitotoksisitas terhadap sel kanker prostat DU 145 menunjukan esktrak etanol, fraksi n-heksan, fraksi etil asetat, dan fraksi air dengan berbagai konsentrasi 31.25, 62.5, 125, 250, dan 500 µg/mL.Fraksi N-heksan memiliki nilai IC50 sebesar 2,80 µg/mL dengan kategori sangat aktif. Hasil aktivitas sitotoksik tersebut dibuktikan dari hasil penafisan fitokimia dari daun pepaya. Metabolit sekunder yang bersifat nonpolar seperti alkaloid pada penafisan fitokimia memperoleh hasil positif. Hal ini membuktikan bahwa alkaloid (carpaine) berkhasiat melawan kanker. Sedangkan pada fraksi air dengan nilai IC50 sebesar 398 µg/mL, fraksi etil asetat sebesar 134 µg/mL dan ekstrak etanol daun pepaya memiliki nilai IC50 sebesar 151 µg/mL bersifat cukup aktif terhadap sel DU 145.
Les rémissions d’usures, moyen d’ajustement d’un équilibre entre profit et réputation (Sienne, XIIIe-XIVe siècles)
Authors: Allingri Matthieu 
Published: May 2022

Les rémissions d’usures, par lesquelles un débiteur absout son créancier de toute usure, ont connu une certaine diffusion en Toscane depuis la fin du XIIIe siècle et traduisent une forme originale de restitution, entre personnes en bonne santé et non in articulo mortis, et surtout ponctuelle, accompagnant parfois le maintien d’une activité de crédit. Après avoir présenté les contours généraux du mouvement des restitutions de male ablata à Sienne et les formes documentaires variées élaborées par les notaires pour ces opérations, l’article analyse à partir d’un ample dossier documentaire les logiques sociales des rémissions. Celles-ci manifestent l’appropriation par les prêteurs d’une démarche de restitution à l’origine imposée par l’Église, pour soigner leur réputation au sein de la communauté sociale et politique tout en évitant d’être confrontés in extremis à un devoir de restitution.
L’usure dans une ville sainte
Authors: Arlinghaus Franz-Josef 
Published: May 2022

À Cologne, au XVe siècle, la question de l’usure a développé une dynamique particulière parce qu’elle se trouvait à l’interface entre les revendications politico-religieuses du seigneur de la ville et les besoins politico-religieux de la commune. L’enjeu des débats n’était cependant pas une question de religion ou de politique, mais plutôt la capacité à décider de l’appartenance d’une personne à la communauté, qui découlait des accusations d’usures. Ainsi ces revendications concurrentielles du seigneur de la ville et de la commune étaient donc principalement de nature sociale et s’appuyaient sur les structures de socialisation prémodernes dans laquelle les communautés, si elles en avaient le pouvoir, cherchaient à régir tous les aspects de la vie de leurs membres. Cette discussion entre la ville et l’évêque a développé une dynamique qui a contribué de manière décisive au développement du concept de «commune» comme autorité responsable pour tous les domaines de la vie sociale et privée des habitants.
Aproximações e Afastamentos de uma Prática Psicológica Baseada em Evidências: análise temática de entrevistas com psicoterapeutas de adolescentes
Authors: Silveira Andressa Secchi , Willers Furtado Luisa Regina , Thais Barbosa Pacheco Janaina 
Published: May 2022

Este estudo objetivou investigar a relação entre o campo de atendimento psicoterapêutico com adolescentes e a área da prática psicológica baseada em evidências (PPBE). Realizou-se um estudo com delineamento qualitativo do qual participaram dez psicólogas terapeutas de adolescentes. Utilizou-se um roteiro de entrevista semiestruturado e as entrevistas foram gravadas e transcritas. Os dados foram submetidos à análise temática, da qual emergiram cinco temas. Os resultados indicam que as participantes percebem déficits na formação que são suplantados por experiência prática e supervisão. Observaram-se inconsistências com relação ao conceito de adolescência e um conhecimento superficial sobre a PPBE. As participantes reconhecem cisão entre os campos da psicoterapia e da pesquisa, o que dificulta a integração do conhecimento produzido por ambos. Os resultados sugerem a aproximação entre pesquisa científica e prática psicológica como passo importante e necessário para a qualificação da psicoterapia de adolescentes e para a ampliação da compreensão acerca do que consiste a PPBE.
Assessments Used by Athletic Trainers to Decide Return-to-Activity Readiness in Patients With an Ankle Sprain
Authors: McCann Ryan S. , Welch Bacon Cailee E. , Suttmiller Ashley M. B. , Gribble Phillip A. , Cavallario Julie M. 
Published: May 2022

ContextAthletic trainers (ATs) often care for patients with ankle sprains. Expert consensus has been established for rehabilitation-oriented assessments (ROASTs) that should be included in ankle-sprain evaluations. However, the methods ATs use to determine return-to-activity readiness after an ankle sprain are unknown.ObjectivesTo identify ATs’ methods for determining patients’ return-to-activity readiness after an ankle sprain and demographic characteristics of the ATs and their methods.SettingOnline survey.DesignCross-sectional study.Patients or Other ParticipantsWe recruited 10 000 clinically practicing ATs. A total of 676 accessed the survey, 574 submitted responses (85% completion rate), and 541 respondents met the inclusion criteria.Main Outcome Measure(s)We distributed an online survey to ATs that asked about their assessment of pain, swelling, range of motion, arthrokinematics, strength, balance, gait, functional capacity, physical activity level, and patient-reported outcomes in deciding return to activity. Descriptive statistics were used to characterize participant demographics and frequencies of the assessment measures used by ATs. Chi-square analysis was conducted to identify relationships between the demographics and assessment selection.ResultsPain, swelling, range of motion, strength, balance, gait, and functional capacity were assessed by 76.2% to 96.7% of ATs. Arthrokinematics, physical activity level, and patient-reported outcomes were assessed by 25.3% to 35.1% of participants. When selecting specific assessment methods, ATs often did not use recommended ROASTs. Athletic trainers with higher degrees, completion of more advanced educational programs, employment in nontraditional settings, more clinical experience, and familiarity with expert consensus recommendations were more likely to use ROASTs.ConclusionsBefore approving return to activity for patients with ankle sprains, ATs did not use some recommended outcomes and assessment methods. Practice in nontraditional settings, more advanced degrees, more clinical experience, and familiarity with expert consensus guidelines appeared to facilitate the use of ROASTs.
Neonates with SARS-CoV-2 infection: spectrum of disease from a prospective nationwide observational cohort study
Authors: Zimmermann Petra , Uka Anita , Buettcher Michael , Fougère Yves , Plebani Margherita , Relly Christa , Schmid Hanna , Ritz Nicole 
Published: May 2022

BACKGROUND: Coronavirus disease 2019 (COVID-19) can be more severe in infants than in older children. To date, only a few case series have reported data on neonates with COVID-19, including mostly asymptomatic neonates who were tested because of exposure to maternal SARS-CoV-2 infection. This study summarises nationwide epidemiological data, clinical characteristics, treatment and outcomes of neonates presenting with symptomatic SARS-CoV-2 infection.
METHODS: Data were prospectively collected through the Swiss Paediatric Surveillance Unit from hospitalised neonates with laboratory-confirmed SARS-CoV-2 infection (positive polymerase chain reaction on a respiratory sample) from 1 March 2020 to 31 September 2021. All 29 paediatric hospitals in Switzerland reported cases.
RESULTS: In total, 73 neonates were included; 7 (10%) were preterm. The median age at presentation was 17 days (interquartile range [IQR] 11–23); 40 (55%) were female. The majority of neonates (64, 88%) were admitted from home. Nine (12%) had a pre-existing medical condition. Overall, the most common symptom recorded was fever in 52 (71%), followed by rhinorrhoea or nasal congestion in 32 (44%) and respiratory distress in 19 (26%). Twenty (27%) neonates presented with fever without a source. Seven (10%) neonates were admitted to an intensive care unit (5 for respiratory failure and 2 for monitoring). One (1%) neonate required inotropic support. The median length of hospital stay in term neonates was 4 days (IQR 3–5). Two (3%) were treated with corticosteroids and 1 (1%) with remdesivir. In total, 60 (82%) neonates had contact with a known or suspected SARS-CoV-2 index case. All of the 71 neonates for whom data were available were discharged to their homes without symptoms.
CONCLUSION: In neonates, COVID-19 mainly presents with fever, and symptoms of upper and lower respiratory tract infection. The clinical course is mostly mild, requiring a short period of hospitalisation. COVID-19 needs to be added as a differential diagnosis in neonates who present with fever without a source. However, the presence of SARS-CoV-2 should not deter from the search for a serious bacterial infection. Further data from surveillance studies are needed to better understand COVID-19 in neonates, guide therapy and to evaluate whether the clinical spectrum is changing with new SARS-CoV-2 variants.
TỔNG HỢP VẬT LIỆU IN DẤU PHÂN TỬ CHỌN LỌC QUERCETIN ỨNG DỤNG PHÂN TÍCH QUERCETIN TRONG MẪU RAU
Authors: NGUYỄN VĂN TRỌNG  , VĂN THANH KHUÊ  
Published: May 2022

Vật liệu polymer in dấu phân tử (MIP) chọn lọc cho quercetin (QC) được tổng hợp bằng phản ứng đồng trùng hợp giữa hai monomer acrylamide (AA) và 4–Vinyl piridine (4-VP) với chất liên kết chéo ethylenglycol dimethacrylate (EGDMA), quá trình đóng khối polyme nhờ chất khơi mào 1,1′-Azobis(cyclohexanecarbonitrile) (ACCN). Khả năng hấp thụ tối đa QC đạt được là 0,2544 mg/g vật liệu MIP. Tính chọn lọc của vật liệu MIP đối với QC là 94,80 %, cao hơn so với Catechin (10,23 %) đồng phân của QC. Qui trình phân tích QC đã được hiệu lực hóa trên nền mẫu rau. Hiệu suất thu hồi đạt được từ 91,16 % đến 94,50 %, giới hạn phát hiện (LOD) và giới hạn định lượng (LOQ) lần lượt là 0,56 ppm và 1,69 ppm. Mẫu rau được thu thập trên thị trường và được thực hiện quy trình phân tích đã nghiên cứu, mẫu được cho qua MIP và phân tích bằng HPLC với đầu dò UV, kết quả đã phản ánh được sự phù hợp của MIP trong việc chọn lọc đối với Quercetin.
O USO DE ANTI-INFLAMATÓRIOS NA GRAVIDEZ E O RISCO DE MALFORMAÇÃO FETAL
Authors: Barreira Djônatas Alves , Silva Karla Beatriz de Carvalho , Silva Luciane Lima da 
Published: May 2022

Objetivou-se analisar as produções científicas acerca dos possíveis efeitos causados pelo uso de anti-inflamatórios durante a gravidez e o risco de malformação fetal. Realizou-se uma revisão integrativa da literatura, que é um método que visa sintetizar os resultados obtidos em pesquisas sobre um assunto ou um problema sistemático, ordenado e abrangente por meio do acesso virtual às bases de dados: Medical Literature Analysis and Retrieval System Online (MEDLINE), acesso por meio do portal PUBMED e por meio do IBECS - Índice Bibliográfico Español em Ciencias de La Salud. Utilizou-se a estratégia PICo para a elaboração da questão de pesquisa da revisão integrativa. Foram selecionados estudos primários contidos em artigos de abordagem qualitativa e quantitativa; estudos que reportem aspectos acerca da gestação e da associação do uso de medicamentos durante esse processo; estudos disponíveis nos idiomas: inglês, português e francês, sem recorte temporal.
Pediatric Hepatic Abscess: A Ten-year Review of the Features and Outcome at the Philippine General Hospital
Authors: Besa Leah Mae C. , Gregorio Germana Emerita V. 
Published: May 2022

Objective. Hepatic abscess is a rare childhood infection with incidence of 1 to 140 per 105 admissions. It has signs and symptoms that mimic other liver diseases. This study determined the clinical, biochemical, microbiologic and imaging features and outcome of children diagnosed with hepatic abscess at a tertiary hospital in Manila.
Method. We conducted a review of medical records of admitted patients aged ≤18 years diagnosed with hepatic abscess in a tertiary referral center from 2007–2018. A diagnosis was confirmed if with (1) fever; (2) imaging study of solitary or multiple hepatic focus; AND (3) at least one more sign or symptom. We computed for mean (SD) for continuous variables or n (%) for categorical variables.
Result. We included 40 patients out of 559, 583 pediatric admissions during the study period (0.007%), with a mean age of 8 years (SD 6.5), and 57% of whom were males. Thirty-seven (92%) were probable pyogenic in etiology, while three were tuberculous abscess. The most common signs and symptoms were fever (100%), abdominal mass (31%), abdominal distension (34%) and weight loss (31%). Majority had anemia (63%) and leukocytosis (89%). The most common imaging finding was a solitary mass (58%) with right lobe (80%) involvement. Nine abscess aspirates yielded Staphylococcus aureus (3), Mycobacterium tuberculosis (3), Klebsiella pneumoniae (1) and no growth (2). All patients were medically treated but eight also required percutaneous/surgical drainage. Majority (36) were discharged improved; four were improving but left before treatment completion.
Conclusion. Majority had pyogenic hepatic abscess, presenting with non-specific clinical and laboratory features. Most abscess were solitary and involved the right lobe. Limited abscess aspirates yielded Staphylococcus aureus and Mycobacterium tuberculosis. Prognosis is favorable with treatment.
Is Face Mask with Face Shield More Effective than Face Mask Alone in Reducing SARS-CoV-2 Transmission? A Systematic Review
Authors: Gregorio Germana Emerita V. , Sanchez-Tolosa Maria Teresa , San Jose Maria Cristina Z. , Infantado Myzelle Anne , Dones III Valentin C. , Dans Leonila F. 
Published: May 2022

Background. The use of face shield in addition to face mask is thought to reduce the transmission of SARS-CoV-2 by blocking respiratory droplets and by preventing one from touching facial orifices.
Objective. To determine the effectiveness of face mask with face shield, compared to face mask alone, in reducing transmission of SARS-CoV-2.
Methods. We searched MEDLINE, Cochrane Library, as well as trial registers, preprint sites and COVID-19 living evidence sites as of 30 September 2021. We included studies that used face shield with face mask versus face mask alone to prevent COVID-19. We screened studies, extracted data, assessed the risk of bias and certainty of evidence using the GRADE approach. Review Manager 5.4 was used to estimate pooled effects.
Results. There is no available direct evidence for face shield plus face mask versus face mask alone in the general public. Five (5) observational studies with very low certainty of evidence due to serious risk of bias and indirectness were included. Participants in all the studies were health care workers (HCWs) who used the face shield with their standard personal protective equipment (PPE). Four (4) of the studies were in the hospital setting (three case control studies, one pre- and post-surveillance study); one was done in the community (one pre- and post-surveillance study) in which HCWs visited the residence of the contacts of SARS-CoV-2 positive patients. The case control studies done in the hospital setting showed a trend toward benefit with the use of face shield or goggle but this was inconclusive (OR 0.85, 95% CI 0.68-1.08) while the pre- and post-surveillance study showed significant benefit when face shield (OR 0.28, 95% CI 0.22-0.37) use became a requirement for HCWs upon hospital entry. In the study done in the community setting, significant protection for HCWs was noted with the use of face shield (OR 0.04, 95% CI 0.00-0.69) but the results were limited by serious risk of bias and imprecision.
Conclusion. In the hospital setting, there was a lower likelihood of COVID-19 infection in HCWs who used a face shield or goggles on top of their PPE. For the general public in the community, there is presently no study on the use of face shield in addition to the face mask to prevent COVID-19 infection.
Factors Associated with Attrition among Residents in Pediatrics: A Mixed-method Study in a Single Center in the Philippines
Authors: Uy Tristan Marvin Z. , Alinea Ma. Cecilia D. 
Published: May 2022

Background. Attrition in residency training can lead to lower workplace morale and increased costs. Finding associated factors can help revise admissions criteria or identify at-risk residents.
Objective. We aimed to determine factors associated with attrition among residents in pediatrics.
Methods. We applied a mixed cross-sectional (survey) and retrospective cohort (records review) study design. Residents who began training in the Philippine General Hospital in 2012–2018 were included. Our primary outcomes were non-completion of training within three years (attrition), completion beyond three years or ongoing training at a delayed year level (off-cycle), and the composite of attrition or off-cycle. Fisher’s exact probability test and t-test were used to compare the non-attrition group versus the attrition group, and the non-attrition group versus the attrition or off-cycle group.
Results. The overall attrition rate and off-cycle rate among 162 residents were 7.41% and 4.32%, respectively. The survey response rate was 73.00%. Four factors were significantly associated with attrition: higher age at entry into the program (p = 0.030), advanced degree (p = 0.009), longer interval from internship completion to start of residency training (p = 0.017), and a lower case presentation score (p = 0.048). The proportion of respondents older than 29 years was significantly higher in the attrition group than the non-attrition group (40.00% vs 0.94%, p = 0.031). Higher age at entry was also significantly associated with the composite outcome (attrition or off-cycle).
Conclusion. Older age at entry, advanced degree, a longer interval from internship, and lower-case presentation scores were associated with attrition among residents in pediatrics from a single center.