bluuebunny/crossref_metadata_2025_split huggingface dataset:
Between the Sustainable Development Narrative and the Environmental Crisis
Authors: Gunansyah Ganes 
Published: July 2022

This study aims to find out what narratives of sustainable development are dominant and what is limited to the presentation of the contents of elementary school textbooks in Indonesia. This study uses quantitative and descriptive content analysis with an instrument in an analysis sheet based on theory. The data sources are 51 elementary thematic textbooks from grades one to six. The study results show that the concept of sustainable development (SDGs) consists of 17 goals and education for sustainable development (ESD). These aspects include social, environmental, economic Sustainability, inclusive development, generally widely spread across all grade levels with varying portions in each grade. The distribution of material related to Social Sustainability (SS) and Environmental Sustainability (EnS) aspects is presented in a small and limited percentage. Meanwhile, materials about aspects of Economic Sustainability (ES) and Sustainability of Inclusive Development (SID) have the most significant portion. Materials on economic growth and activities and the use of natural resources as the mainstay of sustainable development are still dominant, while the roots of the environmental crisis and prevention of ecological damage are still missing.

Keywords: Sustainable Development Goals, Education for Sustainable Development, Textbooks, Environmental Crisis
On the issue of prevention of digital addiction of students of secondary professional educational organizations
Authors: Aibazova M. Yu. , Karasova A. A. , Alimsakaeva R. K. 
Published: July 2022

Introduction. The article examines the problems associated with the digitalization of the education system of secondary vocational education and the impact of this process on students of secondary specialized educational organizations. The paper points out that along with the obvious benefits associated with the need to train personnel for the digital economy by means of using Information and Communications technologies, the digitalization of the education system of the vocational education system has certain risks and costs. Purpose setting. The solution to the problem of digital addiction is based on the development and implementation of a set of measures aimed at its prevention. Methodology of the study. Theoretical methods, comparative analysis and generalization of scientific literature on the problem of studying digital addiction and prevention methods were used; diagnostic methods, methods of result processing. Results. The negative impact of total digitalization on students of secondary vocational education is considered, the emphasis is placed on the fact that along with the advantages, digital educational technologies have a negative impact on personality formation under the condition of uncontrolled use. First of all, this is due to the unpreparedness of the education system to neutralize the level the negative impact of this phenomenon on the personality of students in colleges, schools and other secondary specialized educational institutions. The article points to the need to form a new digital culture in the digital educational environment, the so-called «cyberculture» based on the prevention of digital addiction and compliance with the rules of digital hygiene. The analysis of the impact of the digital educational environment of educational institutions on students determined the need to study the phenomenon of digital hygiene as a factor in preventing the digital dependence of the subjects of the educational process. The literature devoted to the negative impact of the digitalization of the educational process on the mental, physical and intellectual development of students is analyzed. Conclusion. The article reveals the problem of safe behavior in the digital educational space, the issues of leveling the negative processes caused by the digitalization of education through the implementation of a set of measures to prevent digital addiction. The authors have developed and proposed a set of pedagogical conditions for the prevention of digital addiction of students of secondary vocational education.
Digital learning environment as a tool for personalization of distance education programs
Authors: Shamsutdinova T. M. 
Published: July 2022

Introduction. The relevance of the article is due to the realities of the digital transformation of educational process and the increasing requirements for the quality of digital education in the context of distance learning. The article discusses the problems associated with the specifics of distance education. At the same time, it is noted that this type of education has a high practical orientation, but is characterized by the predominance of self-study in the development of educational material. Purpose setting. The purpose of this article is to consider various aspects of designing an electronic educational environment, taking into account the possibility of personalizing the educational trajectory in the context of distance learning. Methodology of the study. This study includes a review of bibliographic sources on the personalization of the educational trajectory by means of an digital learning environment in the context of distance learning. It also includes building a model of the structure of an e-course taking into account the student’s model and a description of an example of implementing an e-course in the LMS Moodle of the Bashkir State Agrarian University. Results. The results of the work include a description and analysis of the problems associated with the organization of distance learning, as well as the results of modeling and testing an electronic course focused on a flexible educational trajectory within the framework of personalization of training. Conclusion. The final part of the work also discusses possible ways to improve the organization of training for part-time students. At the same time, it is concluded that distance learning students are more interested in using flexible individual educational trajectories that take into account their time resources and capabilities. Further direction of studying the problem of personalization of distance learning programs is associated with the study of new technologies for the design of digital educational resources and their practical testing.
Development of a Method for Determination of brucella suis Biovars Using Multilocus Real-time PCR
Authors: Osina N. A. , Sitmbetov D. A. , Domanina I. V. , Lyashova O. Yu. , Shcherbakova S. A. , Kas’yan I. A. , Kas’yan Zh. A. , Bulgakova E. G. 
Published: July 2022

The aim of the study was to develop a methodological approach to determination of Brucella suis biovars through multilocus PCR with real-time registration of results.Materials and methods. We used 16 strains of B. suis of various biovars, B. neotomae and B. canis – 2 strains of each. Determination of the taxonomic affiliation of Brucella strains was carried out according to the Bruce-ladder, Suis-ladder, BRU-DIF protocols. The selection of primers and probes was performed using the software on the website www.genscript.com and the GeneRanner 6.5.52 program. Fragment sequencing according to Sanger was performed on a 3500 XL genetic analyzer in accordance with the manufacturer’s recommendations. Nucleotide sequence homology was assessed using the BLAST algorithm and the GenBank NCBI database.Results and discussion. An analysis of the structural organization of IncP and GI-3 genomic islands has been carried out in B. suis strains of various biovars. It has been established that in strains of B. suis II, IV biovars and B. canis, the terminal part of the BRA0368 gene, comprising 21 nucleotides (repeated in the BRA0367 gene) and the “TAA” stop codon, as well as almost the entire sequence of the BRA0367 gene were lost, owing to homologous recombination in the IncP genome island. A 21-nucleotide direct repeat and the “TGA” stop codon of the BRA0367 gene replaced the analogous region of the BRA0368 gene which resulted in the deletion the size of 185 bp. No differences have been noted in the structure of GI-3 in biovars. The evidence obtained made it possible to develop the approach (SuisDIF) for differentiating B. suis biovars, based on the amplification of genes located in the IncP and GI-3 genomic islands using real-time PCR. Its specificity was confirmed in the study of B. suis strains from the fund of the State Collection of Pathogenic Bacteria of the Russian Research Anti-Plague Institute “Microbe”. The conducted studies expand and supplement the data on the genetic heterogeneity of Brucella species and biovars. The proposed method for differentiating biovars of B. suis using multilocus PCR with real-time registration of results enhances the capacities for Brucella identification using molecular-genetic methods.
Distal Phalangeal Replacement Using a Patient-Specific 3D-Printed Prosthesis
Authors: Penello Daniel , Sussman Phillip , Braunlich Phillip , Rennick Andrew , Alexander Jacob S. 
Published: July 2022

Case:
A 38-year-old man developed a nonunion of a comminuted distal phalanx fracture, which resulted in gross instability of the fingertip. To restore stability, a patient-specific 3D-printed distal phalangeal prosthesis was implanted, and the patient was able to return to his occupation with excellent 2-year outcomes.

Conclusion:
This case highlights the application of 3D printing technology in the development of a patient-specific solution and discusses 6 important considerations for the design and planning process: Patient, Priorities, Point of fixation, Procedure, Problems, and People.
Terahertz bound states in the continuum supported by a composite grating structure with alternating element widths
Authors: Han Zhanghua , Sun Min 
Published: July 2022

Abstract
The deficiency of most current terahertz sources is still a hinder to the advancing of terahertz technology, posing a stringent requirement for the use of artificial structures to enhance the terahertz-matter interactions. With a well-defined enhancement, practical applications can be achieved even when the source power is weak. While metal-based terahertz metamaterials have been extensively investigated for this purpose, their performances are mainly limited by the poor confinement of terahertz waves on metal surfaces, exhibiting low resonance quality factors. In this work, we propose and investigate a simple yet novel scheme of enhancing wave-matter interactions in the terahertz region by exploiting the phenomenon of bound states (BICs) in the continuum. The quasi-BIC effect with ultra-high quality factors and huge local field enhancement is achieved by manipulating two guided mode resonances supported by a slab waveguide with a new type of composite grating composed of two ridge grating arrays with alternating ridge widths. The characteristics of the quasi-BIC effect supported by this kind of structures at the normal incidence, i.e. the symmetry-protected type of BICs, are comprehensively investigated with numerical simulations. The presented results of realizing quasi-BIC can be extended to other structures, providing a novel means of manipulating terahertz-matter interactions.
Symbiotic Wolbachia bacteria in coccinellid parasitoids: genetic diversity, horizontal transfer and recombination
Authors: Shaikevich Elena , Romanov Denis 
Published: July 2022

Abstract
Parasitoids, which constitute about 25% of all insects and attack arthropods of virtually all taxa, are considered the most suitable vectors for horizontal transmission of the symbiotic bacterium Wolbachia among insects. The parasitoids studied in this article develop in the larvae and pupae of ladybirds. For the first time, Wolbachia was found in parasitic wasp species of the genus Homalotylus (Hymenoptera: Encyrtidae) and from the subfamily Tetrastichinae (Hymenoptera: Eulophidae). To characterize the Wolbachia strains, six bacterial housekeeping genes were examined and compared with previously published Wolbachia gene sequences. The same bacterial strains were found in all individuals of each species of parasitic wasps collected in different places and at different times, which indicates the absence of contamination and testifies to the heritability of the symbionts in the studied chalcids. No evidence was found that the parasitic wasps were infected with Wolbachia, identical to the symbionts of their ladybirds hosts. We found one Wolbachia strain, wHom-2, which is a product of bacterial recombination from unrelated insects, including ladybirds. The lack of correspondence between the molecular phylogenies of Wolbachia strains and mithochondrial DNA of their hosts indicate horizontal transfers of Wolbachia among parasitic wasps of the genus Homalotylus and from the subfamily Tetrastichinae.
Niche partitioning and individual specialisation in resources and space use of sympatric fur seals at their range margin
Authors: Salton Marcus , Raoult Vincent , Jonsen Ian D , Harcourt Robert 
Published: July 2022

Abstract
Ecological theory predicts niche partitioning between high level predators living in sympatry as a strategy to minimise the selective pressure of competition. Accordingly, male Australian fur seals Arctocephalus pusillus doriferus and New Zealand fur seals A. forsteri that live in sympatry should partition their broad niches (in habitat and trophic dimensions) in order to coexist. However, at the northern end of their distributions in Australia both are recolonising their historic range after a long absence due to over-exploitation, and their small population sizes suggest competition should be weak and allow overlap in niche space. We found some niche overlap, yet clear partitioning in diet trophic level (δ 15 N values from vibrissae), movement space (horizontal and vertical telemetry data) and circadian activity patterns (timing of dives) between males of each species, suggesting competition remained an active driver of niche partitioning among individuals in these small, peripheral populations. Consistent with individual specialisation theory, broad niches of populations were associated with high levels of individual specialisation for both species, despite putative low competition. Specialists in isotopic space were not necessarily specialists in movement space, further emphasising their diverse individual strategies for niche partitioning. Males of each species displayed distinct foraging modes, with Australian fur seals primarily benthic and New Zealand fur seals primarily epipelagic, though unexpectedly high individual specialisation for New Zealand fur seals might suggest marginal populations provide exceptions to the pattern generally observed among other fur seals.
Glanzmann’s Thrombasthenia during Pregnancy: Case Report and Literature Review
Authors: Sarpietro Giuseppe , GRIMALDI Raffaela , BRESCIA Roberta , MATARAZZO Maria Grazia , CIANCI Antonio 
Published: July 2022

Abstract
Glanzmann's thrombasthenia is an uncommon congenital disease due to an anomaly qualitative or quantitative of the glycoprotein complex GPIIb / IIIA with the consequence of a defective platelet aggregation. Hemorrhages in pregnant women with this bleeding disorder can be severe and may require aggressive treatment with a combined therapy including platelet concentrates, anti-fibrinolytics and rFVIIa. A scheduled plan for obstetric and haematological management should be set in advance. Close clinical observation, laboratory monitoring and immediate access to pro-haemostatic therapies are essential, leading to lower rates of postpartum hemorrhage. A 35 year-old white woman with Glanzmann’s thrombasthenia was followed during pregnancy. A multidisciplinary meeting including gynaecologists, obstetrics, haematologists and anaesthesiologists was arranged for the management of unexpected antepartum haemorrhages, method of delivery and postpartum care. The primary aim of this case report was to evaluate the management of thrombasthenia of Glanzmann during pregnancy, with particular emphasis on the current management of the hemorrhages and the method of delivery, in order to ensure optimal maternal and fetal outcomes.
Antimicrobial activity, antioxidant and chromatographic analysis of Varanus griseus oil extracts
Authors: Ahmad Shakeel , Ruby Tahira , Khan Aleem Ahmed , Shahzad Mirza Imran , Rivera Gildardo , Carriola Diana Victoria Navarrete 
Published: July 2022

Abstract
There is an urgent need to develop natural antimicrobials for the control of rapidly mutating drug-resistant bacteria and poultry viruses. Five extracts were prepared by using diethyl ether, ethyl acetate, methanol, 1-Butanol and n-Hexane from abdominal fats of Varanus griseus locally known as Indian desert monitor. Antibacterial, antioxidant and antiviral activities from oil extracts were done through disc-diffusion method, stable 1,1-diphenyl-2-picrylhydrazil (DPPH) free radical scavenging assay and In Ovo antiviral assay respectively. The gas chromatography mass spectrometry (GCMS) analyses were used to determine principal active compounds and chemical profile of each oil extract. n-Hexane extract showed clear zones of inhibition (ZOI) against Staphylococcus aureus, Escherichia coli and Klebsiella pneumoniae (12 ± 0.5 mm, 9 ± 0.5 mm, 9 ± 0.5 mm) while diethyl ether extract exhibited significant antibacterial activity (11 ± 0.5 mm) against Proteus vulgaris only. In case of drug resistant strains, methanol extract was active (6 ± 0.5 mm) against Staphylococcus aureus whereas n-Hexane extract has shown ZOI 11 ± 0.5 mm against P. aeruginosa. Range of percentage scavenging activity of V. griseus oil extracts from DPPH free radical assay was 34.9–70.7%. For antiviral potential, growth of new castle disease virus (NDV) was effectively inhibited by all five extracts (HA titer = 0–4). The highest antiviral activity against avian influenza virus (H9N2) was observed from methanol, diethyl ether and 1-Butanol oil extracts with HA titers of 2, 2 and 0, respectively. Methanol, diethyl ether, 1-Butanol and n-Hexane oil extracts produced best hemagglutination assay (HA) titer values (0, 0, 4 and 0) against infectious bronchitis virus (IBV). Ethyl acetate and 1-Butanol extract exhibited good antiviral potential against infectious bursal disease virus (IBDV) with indirect hemagglutination assay (IHA) titers of 8 and 4, respectively. Main classes of identified compounds through gas chromatography were aldehydes, fatty acids, phenols and esters. GC-MS identified 11 bioactive compounds in V. griseus oil extracts. It is summarized that V. griseus oil has strong antioxidant activity and good antimicrobial potential because of its bioactive compounds.
Aspergillus species causing invasive fungal disease in Queensland, Australia
Authors: Stewart Adam , Isler Burcu , Simos Peter , Farquhar Drew , George Narelle , Golmayo Mila , Heney Claire 
Published: July 2022

Abstract
Background:Aspergillus species are important causes of invasive fungal disease, particularly among those with an impaired immune system. Increasing reports have revealed a rising incidence of antifungal drug resistance among Aspergillus spp., particularly among cryptic species. Understanding local antifungal susceptibility patterns is paramount to delivering optimal clinical care. Methods:Aspergillus spp. recovered from clinical specimens between 2000 to 2021 from Pathology Queensland were collected. All Aspergillus spp. that underwent antifungal susceptibility testing were recorded and included in the study. Pathology Queensland services all public healthcare facilities in Queensland, Australia. Results:236 Aspergillus spp. were identified from clinical specimens during the study period. The most frequent species identified were Aspergillus fumigatus complex (n=119), Aspergillus flavus (n=35), Aspergillus terreus (n=32) and Aspergillus niger (n=29). Overall, MIC50/90 values for voriconazole, posaconazole, itraconazole, and isavuconazole were 0.25/1, 0.25/0.5, 0.25/0.5, and 0.5/2 mg/L respectively. Echinocandins demonstrated low MIC values overall with micafungin and anidulafungin both having an MIC50/90 of 0.015/0.03 mg/L. A total of 15 cryptic species were identified; high triazole MIC values were observed with a voriconazole MIC50/90 of 2/8 mg/L. From 2017 to 2021 we observed an increase in incidence of isolates with high voriconazole MIC values. There was no difference in voriconazole MIC values between Aspergillus spp. acquired in North Queensland when compared to Southeast Queensland, AustraliaConclusion:Increasing reports of antifungal resistance among Aspergillus spp. is concerning and warrants further investigation both locally and worldwide. Active surveillance of both the emergence of different Aspergillus spp. and changes in antifungal susceptibility patterns over time is crucial to informing clinicians and treatment guidelines.
Mental health experiences of HIV/TB healthcare workers during the COVID-19 pandemic – lessons for provider well-being and support from a qualitative study in seven South African provinces
Authors: Yang Blia , Egg Rafaela , Brahmbhatt Heena , Matjeng Mahlodi , Doro Thanduxolo , Mthembu Zandile , Muzah Batanayi , Foster Brendon , Theunissen Johanna , Frost Ashley , Peetz April , Reichert Katie , Hoddinott Graeme 
Published: July 2022

Abstract
BackgroundCOVID-19 has substantially reshaped health service delivery. Healthcare workers have had to serve more clients, work longer shifts, and operate in conditions of uncertainty. They have experienced multiple stressors related to the additional ‘labour of care’, including managing the frustration of inadequate therapeutic or symptom relief options, witnessing clients dying, and having to give this news to clients’ family members. Ongoing psychological distress among healthcare workers can severely undermine performance, decision-making and well-being. We sought to understand the impact of the COVID-19 pandemic on the mental health experiences of healthcare workers delivering HIV and TB services in South Africa.MethodsWe used a pragmatic and exploratory design to understand HCWs’ mental health experiences with in-depth qualitative data. We implemented the study in ten high HIV/TB burden districts across seven of South Africa’s nine provinces among healthcare workers employed by USAID-funded implementing partners. We conducted in-depth interviews (virtual) with 92 healthcare workers across 10 cadres.ResultsHealthcare workers reported experiencing a range of extreme and rapidly fluctuating emotions because of COVID-19 that negatively impacted on their well-being. Among these, many healthcare workers report experienced a great deal of guilt at their inability to continue to provide quality care to their clients. In addition, a constant and pervasive fear of contracting COVID-19. Healthcare workers’ stress coping mechanisms were limited to begin with, and often further interrupted by COVID-19 and non-pharmaceutical response measures e.g., ‘lockdowns’. Healthcare workers reported a need for greater support for managing the everyday burden of work – not only when experiencing a mental well-being ‘episode’. Further, that whenever they were exposed to stressor events, e.g., supporting a child living with HIV who reports sexual abuse to the healthcare worker, that this this would trigger additional support interventions and not rely on the healthcare worker seeking this out. Further, that supervisors spend more effort demonstrating appreciation toward staff.ConclusionsThe COVID-19 epidemic has added significant mental health burden for healthcare workers in South Africa. Addressing this requires broad and cross-cutting strengthening of everyday support for healthcare workers and centring staff’s mental well-being as core to delivering quality health services.