bluuebunny/crossref_metadata_2025_split huggingface dataset:
The READ-IT study protocol for a feasibility randomised controlled trial of using a support worker/family carer mediated online reading programme to teach early reading skills to adults with intellectual disabilities
Authors: Moody Gwenllian , Coulman Elinor , Gillespie David , Goddard Mark , Grindle Corinna , Hastings Richard P. , Hughes Carl , Ingarfield Kate , Taylor Zac , Denne Louise 
Published: January 2022

Abstract
Background
Many individuals with intellectual disability (ID) have not learnt basic reading skills by the time that they reach adulthood, potentially limiting their access to critical information. READ-IT is an online reading programme developed from the Headsprout® Early Reading (HER®) intervention and supplemented by support strategies tailored for adults with ID. HER® has been successfully used to teach adults with ID to read in a forensic setting by trained staff. The aim of this study is to assess the feasibility of delivering READ-IT to adults with ID by family carers/support workers and will assess whether it would be feasible to conduct a later definitive randomised controlled trial (RCT) of the effectiveness of the programme. The study will aim to contribute to the evidence base on improving outcomes for adults with ID and their caregivers.

Methods
This study is a feasibility RCT, with embedded process evaluation. Forty-eight adults with ID will be recruited and allocated to intervention: control on a 1:1 basis. Intervention families will be offered the READ-IT programme immediately, continuing to receive usual practice and control participants will be offered the opportunity to receive READ-IT at the end of the trial follow-up period and will continue to receive usual practice. Data will be collected at baseline and 6 months post-randomisation.

Discussion
The results of this study will inform a potential future definitive trial, to evaluate the effectiveness of READ-IT to improve reading skills. Such a trial would have significant scientific impact internationally in the intellectual disability field.

Trial registration
ISRCTN11409097
Recurrence and Survival Rates for 1400 Early Breast Tumors Treated with Intraoperative Radiation Therapy (IORT)
Authors: Silverstein Melvin J. , Epstein Melinda S. , Chen Peter , Lin Kevin , Khan Sadia , Snyder Lincoln , Coleman Colleen , Guerra Lisa , Dehkordi-Vakil Farideh , Kim Brian 
Published: January 2022

Abstract
Introduction
Intraoperative radiotherapy (IORT) permits accurate delivery of radiation therapy directly to the tumor bed. We report local, regional, and distant recurrence data along with overall and breast cancer-specific survival for 1400 tumors treated with x-ray IORT.

Methods
A total of 1367 patients with 1400 distinct tumors were enrolled in a registry trial. All received breast conservation surgery and low-energy 50 kV x-ray IORT. To be eligible for excision plus IORT as the only local treatment, histopathology had to confirm tumor size ≤30 mm, margins ≥2 mm, negative lymph nodes, and no extensive lymphovascular invasion. Patients who failed any parameters were referred for additional surgery and/or whole breast radiation therapy (WBRT).

Results
There were 64 ipsilateral local recurrences, 60 were in the IORT only group, 7 axillary recurrences, and 7 distant recurrences. Forty-one local recurrences were within the same quadrant as the index cancer. Twenty-three were in different quadrants. With 62 months of median follow-up, the 5-year Kaplan–Meier probability of any event for all 1400 tumors was 5.27%. For 1175 patients who received IORT only, it was 5.98%. For favorable subtypes, it ranged from 2.41 to 4.31%. Multivariate analysis revealed that biologic subtype luminal A and the addition of WBRT significantly reduced the risk of local recurrence.

Conclusions
The local, regional, and distant recurrence rates observed were comparable to those reported in the literature for IORT but higher than those reported for standard forms of WBRT, hypofractionated treatment, or APBI. IORT benefits include convenience, decreased exposure to medical environments, and low complication rates.
Meshfree Galerkin Method for a Rotating Non-Uniform Rayleigh Beam with Refinement of Radial Basis Functions
Authors: Panchore Vijay 
Published: January 2022

The rotating Rayleigh beam problem is solved with meshfree method where the radial basis functions are explored. Numbers of basis functions have been used for meshfree methods which also include radial basis function. In this paper, the Gaussian radial basis function and multiquadrics radial basis functions are combined to get the new basis function which provides accuracy for higher natural frequencies. The radial basis functions satisfy the Kronecker delta property and it is easy to apply the essential boundary conditions. The Galerkin method is used for weak formulation. The matrices have been derived. The results are obtained for Gaussian radial basis function and new basis function. The results show more accurate values for fourth and fifth natural frequency with new basis function where only six nodes are used within the subdomain of trial and test function. The results are also obtained with conventional finite element method where forty, two node elements are considered. Also, the results are obtained for rotating Euler-Bernoulli beam to observe the difference in results with rotating Rayleigh beam.
Implementation of Low Power Generic 2D FIR Filter Bank Architecture Using Memory-based Multipliers
Authors: Odugu Venkata Krishna , Narasimhulu C. Venkata , Prasad K. Satya 
Published: January 2022

In this paper, a generic filter bank architecture for 2D FIR filter is proposed using block processing, symmetry in the filter coefficients, and memory-based multipliers. The different symmetry filters are considered as sub-filters of the filter bank to decrease the number of multipliers and the desired filter can be selected using control logic to reduce the power consumption. The block processing is incorporated to increase the throughput of the filter. Due to this block processing, memory sharing and memory reuse are achieved to optimize the architecture in terms of area, memory, and power. In each filter, the conventional multipliers are replaced with Distribute Arithmetic (DA) based memory multipliers to decrease the delay, power, and area of each sub-filter. The proposed design is coded by Verilog HDL and synthesized using Cadence Genus tools in 45 nm technology. The physical design is carried out using Cadence Innovus tools. The proposed design results are compared with state-of-the-art works.
Humanization in Educational Environments; Aspects Necessary for Living in School Today
Authors: Tomé José Manuel Salum 
Published: January 2022

While it is true, quality has always been measured through statistics and percentages, often forgetting the training of the whole person.
Now, when we talk about issues such as humanism and education supported by technology, we can fall into extremes: it is common to label technology as the provider of all the evils of today's civilization; or the opposite assumption; to argue that incorporating technologies into education would be the panacea for all the problems it faces and finally, to assume that the subject of the humanities is more typical of actions and attitudes of the past than as a current need, giving vitality to any educational process. However, and fortunately for the educational community, today there are global efforts to make the educational task a human action that minimizes inequities and the abysmal differences that exist in countries like ours. Fernando Reimers says: “Equal educational opportunities must be the priority objective of educational policies, the aim of education must be to contribute to creating just societies. This requires improving the learning environments of the poor, but not only along the paths that have been started over the last decade. This aspect pointed out by Reimers is precisely the central aspect that all educational action must contemplate, the educational policies that are implemented in our country must guarantee, above all, the construction of a just and egalitarian society, strengthening the cultural wealth that we have, with respect to to the diversity of people, their past, their present and especially their future.
An Algorithm of Long Term Evolution-5G Data Transmission Based on Gray Fuzzy Bayesian Network to Monitor Health Parameters
Authors: Chen Ying 
Published: January 2022

Abstract
Aiming at the problems of poor data transmission accuracy and small transmission bandwidth in mobile communication systems, this paper proposes an Long Term Evolution-5G (LTE-5G) data transmission algorithm based on gray theory. On the basis of LTE-5G data mapping, the constellation graph of LTE-5G data transmission was designed so as to complete the one-time formation of data transmission and reduce the influence of Rayleigh noise on the normal mapping process of data. Aiming at the channel error caused by the crossing phenomenon between projections in the transmission constellation and the regional overlapping phenomenon, the gray fuzzy Bayesian network was used to process the gray fuzzy domain and probability data. The results of fuzzy data evaluation were transformed into knowledge in the probability domain by the theory of probability conversion. In the probability knowledge domain, the Bayesian network reasoning algorithm was used to extract the fuzzy data. And then, a grouped fault-tolerant model of transmission constellation was constructed. The protocol fields were repaired by the maximum posterior estimation of the receiver. Finally, the forward error control without the coding sender was completed. Thus, the accuracy of LTE-5G data transmission was improved. Experimental results show that the proposed algorithm has higher data transmission accuracy and bandwidth.
Riesgo cardiovascular en una población escolar con exceso de peso
Authors: Pajuelo-Ramírez Jaime , Bernui-Leo Ivonne , Delgado-Pérez Doris , Palomo-Luck Patricia , Aquino-Ramírez Anthony , Cochachin-Henostroza Omaira 
Published: January 2022

Objetivo. Determinar factores de riesgo cardiovascular en escolares con exceso de peso y medir su asociación con variables sociodemográficas. Métodos. Estudio transversal, analítico. Se encuestó a 2001 escolares mujeres de 6 a 17 años de un Centro Educativo de Lima Metropolitana. Se utilizó el índice de masa corporal para el diagnóstico de exceso de peso (sobrepeso entre 85 y 95p y obesidad ≥ 95p) y la circunferencia de cintura para obesidad abdominal (≥ 90p). HOMA-I para la resistencia a la insulina (RI) (≥ 3,16) y para las alteraciones lipídicas: colesterol total (≥ 200 mg/dL), C-HDL bajo (≤ 40 mg/dL), C-LDL alto (≥ 130 mg/dL), C no HDL (≥ 145 mg/dL) y triglicéridos (≥ 100 y 130 mg/dL) para niñas menores de 9 y de 10 a 19 años, respectivamente. Resultados. El exceso de peso se presentó mayormente en las escolares de 10 a 17 años, en las que nacieron con más de 2500 gr, con más de un antecedente familiar, con lactancia materna exclusiva y en aquellas cuyas madres no tuvieron instrucción. Las alteraciones lipídicas más frecuentes fueron hipertrigliceridemia y C-HDL bajo. El 82% presentó dislipidemia y el 55,4% de obesos RI. La obesidad abdominal estuvo asociada con los antecedentes familiares y la instrucción de la madre. Conclusion. Cuatro de cada cinco niñas con exceso de peso presentó por lo menos una alteración de los lípidos. Una de cada dos obesas tuvo RI.
Características clínicas y epidemiológicas de la endocarditis infecciosa en el Hospital Nacional Dos de Mayo, 2014-2019
Authors: Ferrer Rodríguez Carolina , Fu Llampasi Martha , Espíritu Nora , Parhuana Bando Alejandra 
Published: January 2022

Introducción. La endocarditis infecciosa (EI) es una enfermedad causada por la invasión de organismos patógenos al endotelio cardiaco. Objetivos. Determinar las características clínicas y epidemiológicas de la endocarditis infecciosa en el Hospital Nacional Dos de Mayo, 2014-2019, Lima-Perú. Métodos. Estudio observacional, descriptivo y retrospectivo. Se incluyeron a pacientes mayores de 18 años con diagnóstico de EI según criterios de Duke modificados, que contaban con hemograma, hemocultivo y ecocardiograma. Resultados. Se estudiaron 26 pacientes; la edad promedio fue 46,96 ± 15,6 años, predominó el sexo masculino (57,7%), 15 procedían de Lima y el 50% tenían como grado de instrucción secundaria completa. El 57,7% (n=15) tuvieron hemocultivo negativo, la sintomatología más frecuente fue soplo cardíaco (67,6%), fiebre (26%) y disnea (23,4%), la complicación predominante fue la insuficiencia cardíaca (61%). Las comorbilidades (47,1%) fueron el principal factor de riesgo. La válvula mitral (51,7%) fue la más comprometida. El régimen antibiótico vancomicina + ceftriaxona y vancomicina + gentamicina ambos con 19,2% fueron los más usados. El 84,6% presentaron valores de amplitud de distribución eritrocitaria (ADE) >14,4%. De 10 que fallecieron, 9 tuvieron ADE > 14,4%. Conclusiones. La EI afectó principalmente a mayores de 50 años, de sexo masculino, con comorbilidades concomitantes. La ecocardiografía positiva junto a los criterios menores de Duke fueron predominantes. La mayoría presentó valores elevados de ADE que se relacionaron con la presencia de complicaciones y mortalidad, la cual fue alta.
La pandemia COVID-19 y la salud global desde la perspectiva de la bioética crítica
Authors: Izaguirre Manuel 
Published: January 2022

La globalización y la salud global son consecuencias de las decisiones de los responsables de los gobiernos que generaron las políticas públicas, los modos de producción y desarrollo, sin pensar en el beneficio de las personas y del medio ambiente, actuando sin responsabilidad ética ni social al no centrarse en la persona. El derecho humano prioriza la salud y la equidad para todas las personas, valorando la igualdad en el ámbito de la política global, la globalización económica y tecnológica, y en los problemas globales relacionados al medio ambiente, el calentamiento global y flujos migratorios, cuya comprensión demanda conocer las relaciones entre salud humana, ambiente y riqueza, priorizando la supervivencia óptima de la humanidad, meta final de la bioética global, para garantizar la dignidad humana y los derechos humanos universales, incluido el derecho a la salud. “La moralidad universal es producto histórico de la experiencia humana”, al ser prácticas y lecciones aprendidas en el transcurrir del tiempo. Por consiguiente, las decisiones éticas para solucionar conflictos morales durante la pandemia deben ser racionales y no solo emocionales, circunscritas en el ámbito de lo social y de la justicia distributiva con la finalidad de salvar el mayor número de vidas basado en los principios de la ética social, contraponiendo los principios éticos del ámbito individual como la autonomía que es privilegiada cuando no perjudica a otros y la justicia que la limita cuando se priva la libertad con fines de aislamiento.
Primer reporte de Candida auris en Perú
Authors: Yagui-Moscoso Martín , Paucar-Miranda Celia J. , Sandoval-Ahumada Roxana E. , López-Martínez Rosa L. , Terrel-Gutierrez Leonel , Zurita-Macalapu Susana , Urcia-Ausejo Flor , Flores-León Diana , Gavilan-Chávez Ronnie , Quispe-Pardo Zenobia 
Published: January 2022

Candida auris es un hongo emergente que ha cobrado en corto tiempo gran relevancia como problema de salud pública mundial. Se reporta por primera vez en el Perú la presencia de Candida auris en 3 pacientes adultos internados en un hospital nacional de alta complejidad en el último trimestre del año 2020 en plena pandemia de COVID-19. Los pacientes fueron hospitalizados en UCI, sin embargo, solo en 2 pacientes se aisló dicho germen mientras estaban hospitalizados en UCI. Los pacientes tenían varias comorbilidades y tiempos prolongados de hospitalización desde su admisión hasta tener su primer cultivo positivo a C. auris. Todos los pacientes adquirieron una infección nosocomial bacteriana en algún momento de su hospitalización y recibieron antibióticos de amplio espectro. Todas las cepas aisladas eran resistentes a Fluconazol. El equipo de control de infecciones del hospital reforzó las medidas de contención y el Ministerio de Salud emitió una alerta epidemiológica.
AHMED VESÎM DÎVÂNI (İnceleme-Metin) (ISBN: 978-975-6122-65-7; Erzurum: Salkımsöğüt Yayınevi; Yıl: 2010; s.s. 320)
Authors: CİĞA Özkan 
Published: January 2022

Günümüzde klasik Türk şiiri alanında yapılan pek çok incelemeye rağmen kütüphanelerde çeşitli nedenlerden ötürü gözden kaçmış eserlerin mevcudiyeti şüphe götürmez bir gerçektir. Bu eserlerin ilmî bir disiplinle detaylı bir şekilde incelenip değerlendirilmesi edebî zenginliğimizin ortaya konulması açısından büyük bir önem arz etmektedir.
Bu bağlamda, Prof. Dr. İbrahim Halil Tuğluk, XVIII. yüzyıl şairlerinden biri olan Ahmed Vesîm’in Dîvânı’nın iki nüshasını tespit ederek eser üzerine ilmî hüviyete haiz bir inceleme gerçekleştirmiştir. Salkımsöğüt yayınevi tarafından 2010 yılında yayımlanan bu çalışma, toplam 320 sayfadan oluşmaktadır. Tuğluk, bu çalışmasında XVIII. yüzyıl, Osmanlıda zihniyet değişikliğinin yaşandığı bir dönemde yaşayan ve Mahallîleşme, Sebk-i Hindî gibi üslup hareketliliğinin etkisiyle şiirin yeni bir oluşuma kapı araladığı dönemde şiir yazan Ahmed Vesîm’in Dîvânı’nı incelemiştir. Ahmed Vesîm, “Sebk-i Hindî’nin tesirinde, kapalı ve ağır bir üslupla daha çok nazire tarzında şiirler kaleme almış” (Tuğluk, 2010:7) bir şahsiyet olduğu için yazar, özellikle şairin üslubunu, edebî yönünü ön plana çıkaran bir inceleme gerçekleştirmiştir.
Determinants of farm-level adaptation strategies to flood: insights from a farm household-level survey in coastal districts of Odisha
Authors: Padhan Niranjan , Madheswaran S. 
Published: January 2022

Abstract
Farmers choose different strategies to cope with disasters. The scientific information on what adaption strategies do farmers across different socio-economic and regional strata choose to cope with disasters can help policymakers to make informed farm-level support interventions. Odisha is a flood-prone state in eastern India. The flood adaptation strategy choices of farmers in Odisha have not been much studied in the literature. Along with identifying the most commonly adopted ex ante and ex post adaptation strategies of farmers, we also identified the common factors influencing the choice of these adaptation strategies. We used the Likert scale and the ordered probit model to analyse the primary data collected from the field survey conducted at the three selected coastal districts. It finds that migration, reduction in food consumption, and pest and disease management are the most common ex post strategies, whereas stocking of foodgrains and usage of flood-resistant seeds are the most common ex ante strategies adopted by the farmers. It also identifies that education, family size and the size of landholding are the main determinants of ex post adaptation strategies, whereas age, the size of landholding and family income are the major determinants of ex ante coping strategies.
Longitudinal Changes of COVID-19 Symptoms in Social Media: Observational Study
Authors: Sarabadani Sarah , Baruah Gaurav , Fossat Yan , Jeon Jouhyun 
Published: January 2022

Background
In December 2019, the COVID-19 outbreak started in China and rapidly spread around the world. Many studies have been conducted to understand the clinical characteristics of COVID-19, and recently postinfection sequelae of this disease have begun to be investigated. However, there is little consensus on the longitudinal changes of lasting physical or psychological symptoms from prior COVID-19 infection.

Objective
This study aims to investigate and analyze public social media data from Reddit to understand the longitudinal impact of COVID-19 symptoms before and after recovery from COVID-19.

Methods
We collected 22,890 Reddit posts that were generated by 14,401 authors from March 14 to December 16, 2020. Using active learning and intensive manual inspection, 292 (2.03%) active authors, who were infected by COVID-19 and frequently reported disease progress on Reddit, along with their 2213 (9.67%) longitudinal posts, were identified. Machine learning tools to extract biomedical information were applied to identify COVID-19 symptoms mentioned in the Reddit posts. We then examined longitudinal changes in individual physiological and psychological characteristics before and after recovery from COVID-19 infection.

Results
In total, 58 physiological and 3 psychological symptoms were identified in social media before and after recovery from COVID-19 infection. From the analyses, we found that symptoms of patients with COVID-19 lasted 2.5 months. On average, symptoms appeared around a month before recovery and remained for 1.5 months after recovery. Well-known COVID-19 symptoms, such as fever, cough, and chest congestion, appeared relatively earlier in patient journeys and were frequently observed before recovery from COVID-19. Meanwhile, mental discomfort or distress, such as brain fog or stress, fatigue, and manifestations on toes or fingers, were frequently mentioned after recovery and remained as intermediate- and longer-term sequelae.

Conclusions
In this study, we showed the dynamic changes in COVID-19 symptoms during the infection and recovery phases of the disease. Our findings suggest the feasibility of using social media data for investigating disease states and understanding the evolution of the physiological and psychological characteristics of COVID-19 infection over time.
Respon Karakter Pengisian Biji dan Hasil terhadap Pemberian Pupuk Urea pada Empat Varietas Padi
Authors: Renica Nurhermawati  , Iskandar Lubis  , Ahmad Junaedi  
Published: January 2022

Unsur nitrogen (N) memainkan peran penting pada tanaman padi termasuk dalam meningkatkan hasil tanaman. Terdapatnya perbedaan hasil gabah pada masing-masing varietas padi sangat erat kaitannya dengan karakter pengisian biji. Dengan demikian, respon karakter pengisian biji dan hasil dari varietas padi yang berbeda terhadap kondisi N di dalam tanah sangat relevan untuk dikaji. Tujuan penelitian ini adalah untuk mengkaji respon karakter pengisian biji dan hasil empat varietas padi terhadap pemberian pupuk urea. Penelitian ini dilaksanakan di lahan persawahan Desa Petapahan, Kampar, Riau pada bulan September sampai Desember 2020. Rancangan percobaan yang digunakan adalah rancangan petak terbagi dalam rancangan acak kelompok. Dosis pupuk urea (0 kg ha-1 dan 250 kg ha-1) merupakan faktor pertama sebagai petak utama, sedangkan varietas (Hipa 18, IPB 3S, Ciherang dan Way Apo Buru) merupakan faktor kedua sebagai anak petak. Berdasarkan hasil penelitian diketahui bahwa Hipa 18 merupakan varietas padi yang melakukan remobilisasi asimilat dalam jumlah yang paling banyak selama fase pengisian biji. Selain itu, Hipa 18 juga menggunakan N dalam persentase yang paling tinggi untuk pembentukan dan perkembangan malai dibandingkan varietas lainnya. Respon tertinggi untuk semua komponen hasil juga diperoleh dari Hipa 18 kecuali bobot 100 biji. Hasil penelitian ini dapat digunakan sebagai dasar dalam merakit varietas padi yang memiliki karakterisik hasil tinggi. Disamping itu, pemupukan yang presisi untuk masing-masing varietas padi dapat direkomendasikan.
Kata kunci: bobot kering, fotosintesis, indeks luas daun, kandungan N daun, remobilisasi asimilat