bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Singapore International Commercial Court (SICC)  an Alternative to International Arbitration?
Authors: Landbrecht Johannes 
Published: April 2022

The SICC, a division of the Singapore High Court, opened its doors about a year ago. This new state court is the latest addition to Singapore’s comprehensive strategy for providing dispute resolution services. To sum it up in one sentence, the SICC will have a familiar ring to users of English Commercial Court litigation, as the English Commercial Court and its transnational success provided a model and an inspiration for the architects of the SICC structure. The SICC’s rules on jurisdiction and procedure follow well-known patterns of many common law systems. However, and notwithstanding its common law origin, the SICC is also set up to cater to the specific needs and expectations of civil law users and practitioners, and in particular in a transnational and mixed legal context. The SICC was established to complement, not to replace, Singapore’s arbitration landscape. The SICC should therefore be welcomed as an interesting additional option for dispute resolution in the region, although it might not, for most European users, be an alternative to international arbitration.
الازدهار النفسي لدى الطالبات الجامعيات الممارسات وغير الممارسات للرياضة
Authors: اخلاص عبدالحميد محمد  , ساهرة رزاق كاظم  
Published: March 2022

يهدف البحث الى دراسة الازدهار النفسي لدى الطالبات الجامعيات في ظل الظروف التي يمر بها القطر العراقي, وللتعرف على مستوى ابعاد والمجموع العام للازدهار النفسي بين طالبات التربية البدنية وعلوم الرياضة وبعض طالبات الكليات الاخرى , حيث تم تبني مقياس الازدهار النفسي لعمار عبد الامير الزويني وكان يضم ( 60) فقرة موزعة على خمسة ابعاد وهي البعد الاول المشاعر الايجابية والبعد الثاني الاندماج النفسي والبعد الثالث معنى الحياة والبعد الرابع العلاقات الايجابية والبعد الخامس الانجاز وقد قامت الباحثتان باستخراج الاسس العلمية للمقياس وبعد اثبات صلاحية المقياس تم توزيعه على (80) طالبة من طالبات المرحلة الثالثة في جامعة بغداد للعام الدراسي 2021 وبعد تحليل البيانات احصائيا توصلت الباحثتان بوجود مستوى جيد لإبعاد والمجموع العام لطالبات الجامعيات مع تفوق الطالبات الممارسات للرياضة على الطالبات الغير ممارسات للرياضة في الابعاد والمجموع العام لمقياس الازدهار النفسي
Monoterpenes in Plants- a mini review
Authors: Chern Lee Yuan , Shukor M.Y. , Muse Radzali 
Published: April 2022

Monoterpenes are abundant chemicals in plants that are formed by a multitude of enzymes and present a challenge both in identification and understanding the synthetic enzymes involves in their formation and fate. They are especially abundant in fragrance-producing plants. The enyme that produce them are numerous but several key enzymes have been identified and are discussed in this short review.
Statistical Evaluation of the Mathematical Modelling on the Molybdenum Reduction Kinetics of a Molybdenum-reducing Bacterium
Authors: S. Shukor M. , Shukor Mohd Yunus Abd 
Published: April 2022

Molybdenum is a global pollutant that has been increasingly found to be toxic tospermatogenesis in several animal model studies. Thus its removal and the studies of its reduction kinetics for removal are very important. In a previous study (1), three kinetic models; i.e. Haldane, Luong and Monod were evaluated to study the reduction kinetics of the molybdenum-reducing bacterium Bacillus sp. strain A.rzi. We revisited the model used in this bacterium and extend the study by incorporating more reduction kinetics models such as Hans- Levenspiel, Yano, Aiba, Webb, Hinshelwood and Teissier. We then evaluated the accuracy of the fitted model using statistical analysis. The best model was Han Levenspiel instead of Luong as proposed previously with the majority of the statistical evaluation such as the lowest values for RMSE, the highest adjusted R2 values and with Bias Factor and Accuracy Factor nearest to unity (1.0) indicated that the model was the best. The calculated values for the Han-Levenspiel constants qmax (the maximum specific substrate reduction rate (hâˆ’1), Sm (the critical inhibitor concentration (mM) above which reactions stops), Ks (concentration of substrate giving half maximal reduction rate (mM) and the empirical constants m and n (both dimensionless) were 3.832, 106.16, 48.19, -1.271 and 1.001, respectively. The true qmax value where the gradient forthe slope is zero was 1.107 h-1 at 38 mM molybdate as a substrate. The results indicate that the exhaustive use of mathematical models provides new understanding of the way molybdenum inhibits production into molybdenum blue in bacterium. This can provide new knowledge on ways to predict progress of molybdenum reduction in the laboratory and during bioremediation works.
Evaluation of several mathematical models for fitting the growth of sludge microbes on PEG 600
Authors: Halmi Mohd Izuan Effendi , Shukor Mohd Shukri , Masdor Noor Azlina , Shamaan Nor Aripin , Shukor Mohd Yunus 
Published: April 2022

Polyethylene glycols (PEGs) are employed in numerous sectors. PEGs are nephrotoxic and their biodegradation by microbes could be a potential tool for bioremediation. Numerous bacterial growth studies neglect primary modelling even though modelling exercises can reveal important parameters. In this work we modelled the growth of the sludge microbes on PEG 600 based on available published work in the literature using several growth models such as modified logistic, modified Gompertz, modified Richards, modified Schnute, Baranyi-Roberts, Von Bertalanffy, Huang and the Buchanan three-phase linear model. Statistical analysis results indicated that the modified Gompertz model was the best with highest adjusted R2, lowest RMSE and AICc values and Bias and Accuracy Factor values closest to unity. The results from this work can be used in the further optimization works of this process in the future.
COVID-19 Self-Screening in Emergency Unit Nurses
Authors: Sandy Tualaka Yunita 
Published: March 2022

Health care personnel especially in the emergency unit is most vulnerable to COVID-19 because the probability of direct contact with infected people is very high. The number of health workers who died due to COVID 19 starting from 7th May is 202 people. Objective: To know COVID-19 exposure risk to emergency unit nurses. Methods: This was descriptive quantitative research. The population was nurses working in the emergency units with 58 respondents taken with accidental sampling technique. Data were collected using questionnaires consisting of 20 questions distributed online with Google form. Results: The result shows most of the respondents have a low risk of COVID19 with a total of 56 people (96.6%) and 2 people (3.48%) have high risk. Conclusion: The majority of emergency unit nurses currently have a low exposure risk of COVID-19.
Keywords: Self-screening, COVID-19, emergency unit nurses
Review of the measurement of Dynamic Capabilities
Authors: Martínez de Miguel Pablo , García Martínez Antón , Montes-Botella José-Luis 
Published: March 2022

Objective: The objective of the paper is to identify relations between digital transformation and the micro-foundations of the dynamic capabilities within the automotive sector.Methodology: To achieve the previous goal, the analysis is based on a literature review and expert judgments through a survey. Then, from a quantitative methodology of exploratory analysis the correct assignment of the indicators as well as a SEM analysis of structural equations with latent variables as a statistical technique has been used.
Results: Therefore, using the indicators already presented, it has been possible to establish the relationship model. We have been able to present how all these indicators correspond to dynamic capabilities, and it is the digital transformations that generate them.
Limitations: the research presents some limitations that should be considered when contextualizing the work done. The most representative one is the difficulty of obtaining a larger sample, because out of 142 surveys, only 42 responses were obtained, due to the limited time respondents had to attend to the researcher.Practical implications: the automotive industry is continuously impacted with the introduction of new technologies, which makes it necessary for organizations to adapt to the fast pace of growth. Furthermore, companies that understand the importance of digital transformation show more modern work styles, consider user preferences and the information they can obtain from the context.
Implicit finite element analysis of ductile fracture of a steel frame under cyclic deformation
Authors: Ohsaki Makoto , Fujiwara Jun , Miyamura Tomoshi , Namba Hisashi 
Published: April 2022

AbstractA ductile fracture model is implemented to an elastoplastic constitutive model of steel material for large‐scale finite element analysis of steel frames. The stress modified critical strain model is extended to simulate the structural response after initiation of ductile fracture. The yield stress, Young's modulus, as well as the stress are reduced using the fracture variable. Positive definiteness of the material tangent stiffness matrix is always maintained, and the unbalanced loads are carried over to the succeeding step to analyze the responses in the range of degrading strength using an implicit finite element analysis. It is shown using a notched rod model and a double notched plate that the proposed model can simulate steep stiffness degradation due to strain localization after ductile fracture. Applicability to a large‐scale finite element analysis is investigated using a component frame of moment frame subjected to cyclic forced deformation.
Dual‐Mode Organic Electrochemical Transistors Based on Self‐Doped Conjugated Polyelectrolytes for Reconfigurable Electronics
Authors: Nguyen‐Dang Tung , Chae Sangmin , Chatsirisupachai Jirat , Wakidi Hiba , Promarak Vinich , Visell Yon , Nguyen Thuc‐Quyen 
Published: April 2022

AbstractReconfigurable organic logic devices are promising candidates for next generations of efficient computing systems and adaptive electronics. Ideally, such devices would be of simple structure and design, be power efficient, and compatible with high‐throughput microfabrication techniques. This work reports an organic reconfigurable logic gate based on novel dual‐mode organic electrochemical transistors (OECTs), which employ a self‐doped conjugated polyelectrolyte as the active material, which then allows the transistors to operate in both depletion mode and enhancement mode. Furthermore, mode switching is accomplished by simply altering the polarity of the applied gate and drain voltages, which can be done on the fly. In contrast, achieving similar mode‐switching functionality with other organic transistors typically requires complex molecular design or multi‐device engineering. It in shown that dual‐mode functionality is enabled by the concurrent existence of anion doping and cation dedoping of the films. A device physics model that accurately describes the behavior of these transistors is developed. Finally, the utility of these dual‐mode transistors for implementing reconfigurable logic by fabricating a logic gate that may be switched between logic gates AND to NOR, and OR to NAND on the fly is demonstrated.
Superhydrophobic Ag‐Decorated CuO Nanowire Arrays with Analyte‐Concentrating and Self‐Cleaning Binary Functions for Ultrasensitive and Recyclable Surface‐Enhanced Raman Scattering
Authors: Meng Tingting , Guo Yingcen , Shi Meirong , Wang Huichao , Fu Nuo , Liu Zhiping , Huang Bo , Lei Chao , Cao Jing , Deng Ziwei 
Published: April 2022

AbstractSurface‐enhanced Raman scattering (SERS) is considered a promising analytical technique for the detection of analytes. Considering the practical SERS detection, it is necessary to develop low‐cost, highly sensitive, and recyclable SERS‐active substrates. Here, a simple and flexible approach is proposed to fabricate a superhydrophobic Ag‐decorated CuO (named as CuO@Ag) nanowire array substrate with analyte‐concentrating and self‐cleaning binary functions for ultrasensitive and recyclable SERS detection. During this process, a superhydrophobic CuO@Ag nanowire array is made via fabrication of a CuO nanowire array by oxidizing and calcinating an ordered porous anodic aluminum oxide template on Cu foil, and following with Ag sputtering deposition on CuO nanowire array. Remarkably, this SERS substrate exhibits ultrasensitive SERS detection ability attributed to superhydrophobic plasmonic metal nanostructured arrays with high analyte‐concentrating ability and excellent photocatalytic capability due to this metal‐semiconductor composite nanostructure. These advantageous properties allow for SERS detection of malachite green with a limit of detection of 6.73 × 10−13 m and self‐cleaning via photodegradation of adsorbed analytes with visible‐light illumination. Consequently, it achieves recyclable SERS detection. This research demonstrates a simple and flexible approach for fabricating recyclable SERS‐active substrate, which expands the practical SERS applications in chemical and biological analysis, food safety, and healthcare.
Photoinduced Three‐Component Difluoroamidosulfonylation/Bicyclization: Regioselectivity Synthesis of Seven‐Membered Dibenzosultams
Authors: Zheng Xiangyun , Shen Qitao , Yin Chuanliu , Li Lianghao , Zhong Tianshuo , Yu Chuanming 
Published: April 2022

AbstractA mild and safe photochemical methodology has been developed to access difluoroamidosulfonylated dioxodibenzothiazepines via three‐component radical bicyclization cascades. This photocatalyst‐free transformation avoids cumbersome photocatalyst removal procedure and potential toxicity. Mechanistic experiments reveal the generation of an electron donor‐acceptor (EDA) complex in the reaction process. Moreover, synthetic value of the protocol is further demonstrated by gram‐scale reaction, conversion of product and total synthesis of antidepressant drug.magnified image
The germline p53 activation syndrome: A new patient further refines the clinical phenotype
Authors: Kumar Runjun D. , Tosur Mustafa , Lalani Seema R. , Mahoney Donald H. , Bertuch Alison A. 
Published: April 2022

AbstractThe tumor suppressor p53 has well known roles in cancer development and germline cancer predisposition disorders, but increasing evidence supports the role of activation of this transcription factor in the pathogenesis of inherited bone marrow failure and chromosomal instability disorders. Here we report a patient with red cell aplasia, which was steroid responsive, as well as intellectual disability, seizures, microcephaly, short stature, cellular radiosensitivity, and normal telomere lengths, who had a germline heterozygous C‐terminal frameshift variant in TP53 similar to others that activate the transcription factor. This is the third reported individual with a germline p53 activation syndrome, with several unique features that refine the clinical disease associated with these variants.
An Anionic Dinuclear Ruthenium Dihydrogen Complex of Relevance for Alkynegem‐Hydrogenation
Authors: Biberger Tobias , Nöthling Nils , Leutzsch Markus , Gordon Christopher P. , Copéret Christophe , Fürstner Alois 
Published: April 2022

AbstractDuring an investigation into the fate of ruthenium precatalysts used for light‐driven alkynegem‐hydrogenation reactions with formation of Grubbs‐type ruthenium catalysts, it was found that the reaction of [(IPr)(η6‐cymene)RuCl2] with H2under UV‐irradiation affords an anionic dinuclear σ‐dihydrogen complex, which is thermally surprisingly robust. Not only are anionic σ‐complexes in general exceedingly rare, but the newly formed species seems to be the first example lacking any structural attributes able to counterbalance the negative charge and, in so doing, prevent oxidative insertion of the metal centers into the ligated H2from occurring.
Electronic Tuning in Reaction‐Based Fluorescent Sensing for Instantaneous and Ultrasensitive Visualization of Ethylenediamine
Authors: Ke Yulei , Liu Yuan , Zu Baiyi , Lei Da , Wang Guangfa , Li Jiguang , Ren Wenfei , Dou Xincun 
Published: April 2022

AbstractManipulation of a multi‐physical quantity to steer a molecular photophysical property is of great significance in improving sensing performance. Here, an investigation on how a physical quantity rooted in the molecular structure induces an optical behavior change to facilitate ultrasensitive detection of ethylenediamine (EDA) is performed by varying a set of thiols. The model molecule consisting of a thiol with dual‐carboxyl exhibits the strongest fluorescence, which is ascribed to the electron‐donating ability and prompted larger orbital overlap and oscillator strength. The elevated fluorescence positively corelated to the increased EDA, endowing an ultrasensitive response to the nanomolar‐liquid/ppm‐vapor. A gas detector with superior performance fulfills a contactless and real‐time management of EDA. We envisage this electron‐tuning strategy‐enabled fluorescence enhancement can offer in‐depth insight in advancing molecule‐customized design, further paving the way to widening applications.
Expanding the Scope of Metastable Species in Hydrogen Bonding‐Directed Supramolecular Polymerization
Authors: Matern Jonas , Fernández Zulema , Bäumer Nils , Fernández Gustavo 
Published: April 2022

AbstractWe reveal unique hydrogen (H‐) bonding patterns and exploit them to control the kinetics, pathways and length of supramolecular polymers (SPs). New bisamide‐containing monomers were designed to elucidate the role of competing intra‐ vs. intermolecular H‐bonding interactions on the kinetics of supramolecular polymerization (SP). Remarkably, two polymerization‐inactive metastable states were discovered. Contrary to previous examples, the commonly assumed intramolecularly H‐bonded monomer does not evolve into intermolecularly H‐bonded SPs via ring opening, but rather forms a metastable dimer. In this dimer, all H‐bonding sites are saturated, either intra‐ or intermolecularly, hampering elongation. The dimers exhibit an advantageous preorganization, which upon opening of the intramolecular portion of the H‐bonding motif facilitates SP in a consecutive process. The retardation of spontaneous self‐assembly as a result of two metastable states enables length control in SP by seed‐mediated growth.
New 1,2,4‐oxadiazole/pyrrolidine hybrids as topoisomerase IV and DNA gyrase inhibitors with promising antibacterial activity
Authors: Frejat Firas O. A. , Cao Yaquan , Wang Lihong , Zhai Hongjin , Abdelazeem Ahmed H. , Gomaa Hesham A. M. , Youssif Bahaa G. M. , Wu Chunli 
Published: April 2022

AbstractA series of hybridized pyrrolidine compounds with a 1,2,4‐oxadiazole moiety were synthesized to develop effective molecules against the enzymes DNA gyrase and topoisomerase IV (Topo IV). Compounds 8–20 were developed based on a previously disclosed series of compounds from our lab, but with small structural modifications in the hopes of increasing the compounds' biological activity. In comparison to novobiocin, with IC50 = 170 nM, the findings of the DNA gyrase inhibitory assay revealed that compounds 16 and 17 were the most potent of all synthesized derivatives, with IC50 values of 180 and 210 nM, respectively. Compound 17 had the strongest inhibitory effect against Escherichia coli Topo IV of all the synthesized compounds, with an IC50 value of 13 µM, which was comparable to novobiocin (IC50 = 11 µM). Therefore, hybrids 16 and 17 appeared to be potential dual‐target inhibitors. In the minimal inhibitory concentration (MIC) assays, compound 17 outperformed ciprofloxacin against E. coli, with an MIC of 55 ng/ml, compared to 60 ng/ml for ciprofloxacin. Finally, the docking study, along with the in vitro experiments, supports our promising approach to effectively develop potent leads for further optimization as dual DNA gyrase and Topo IV inhibitors.
Synthesis, Characterizations and Applications of Fluoroazaphosphatranes
Authors: Manick Anne‐Doriane , Dutasta Jean‐Pierre , Nava Paola , Dufaud Véronique , Gao Guohua , Chatelet Bastien , Martinez Alexandre 
Published: April 2022

AbstractHaloazaphosphatranes are the halogenated parents of proazaphosphatranes, also known as Verkade's superbase. While the synthesis of iodo‐, bromo‐ and chloroazaphosphatranes was reported more than thirty years ago by J. G. Verkade, the first synthesis of fluoroazaphosphatranes was only described in 2018 by Stephan et al. Currently, no common and versatile procedure exists to access fluoroazaphosphatranes platform with different structural characteristics. In this report, a new and simple synthesis of this class of compounds was developed based on the nucleophilic attack of the fluoride anion on chloroazaphosphatrane derivatives with good to high isolated yields for the corresponding fluoroazaphosphatranes (70–92%). The scope of the reaction was widened to fluoroazaphosphatranes bearing various substituents and X‐ray molecular structures of two of them are reported. The stability of fluoroazaphosphatranes toward nucleophilic solvents like water has been investigated. As they revealed much more robust cations than their chloroazaphosphatrane parents, their chloride salts were tested as organocatalysts for the formation of cyclic carbonates from epoxides and CO2. Fluoroazaphosphatranes proved to be both efficient and stable catalytic systems for CO2 conversion with catalytic activities similar to those of azaphosphatranes, and no decomposition of the cation was observed at the end of reaction.
A Catalogue of Orthogonal Complementary Ligand Pairings for Palladium(II) Complexes
Authors: Buchanan Jason S. , Preston Dan 
Published: April 2022

AbstractMolecular recognition is a form of information transfer, seen in the base pairing in DNA which is derived from the identity (acceptor or donor) and number of hydrogen bond sites within each base. Here we report bis‐ligand palladium(II) complexes that exhibit similar complementarity. Pd(II) has square planar four‐coordinate geometry, giving control over ligand orientation and denticity. Pairings were developed using ligand denticity (3 : 1 or 2 : 2), and hydrogen bond capability (AA:DD or AD:DA) or lack thereof. Five pairings were investigated, with two sets of four being found fully orthogonal. The two 3 : 1 pairings exhibited limited ligand exchange. The extent of this exchange varied dependant on solvent from 2 : 1 (desired to undesired) to 6 : 1. A reliable and varied set of ligand pairs have therefore been developed for bis‐ligand coordination sphere engineering in pursuit of sorting for complex molecular architectures and molecular‐level information storage and transfer events.