bluuebunny/crossref_metadata_2025_split huggingface dataset:
From the Heterogeneity Problem to a Natural‐Kind Approach to Pleasure
Authors: Broi Antonin 
Published: June 2022

AbstractThe heterogeneity problem, which stems from the alleged difficulty of finding out what all pleasant experiences have in common, is largely considered as a substantial issue in the philosophy of pleasure, one that is usually taken as the starting point for theorizing about the essence of pleasure. The goal of this paper is to move the focus away from the heterogeneity problem and toward an alternative approach to pleasure. To do this, I first show that, although the approach stemming from the heterogeneity problem has led to an interesting discussion about the essence of pleasure, it has usually endorsed an introspectionist methodology and other problematic assumptions that have led to doubtful results. I thus propose a natural‐kind approach to pleasure, which seeks to determine what, if any, the natural kind of pleasure would consist in. This approach broadens the investigation of pleasure by enabling the use of a larger range of methodological tools, thus opening new promising directions for research.
Natural allelic variation ofGmST05controlling seed size and quality in soybean
Authors: Duan Zongbiao , Zhang Min , Zhang Zhifang , Liang Shan , Fan Lei , Yang Xia , Yuan Yaqin , Pan Yi , Zhou Guoan , Liu Shulin , Tian Zhixi 
Published: June 2022

SummarySeed size is one of the most important agronomic traits determining the yield of crops. Cloning the key genes controlling seed size and pyramiding their elite alleles will facilitate yield improvement. To date, few genes controlling seed size have been identified in soybean, a major crop that provides half of the plant oil and one quarter of the plant protein globally. Here, through a genome‐wide association study of over 1800 soybean accessions, we determined that natural allelic variation atGmST05(Seed Thickness 05) predominantly controlled seed thickness and size in soybean germplasm. Further analyses suggested that the two major haplotypes ofGmST05differed significantly at the transcriptional level. Transgenic experiments demonstrated thatGmST05positively regulated seed size and influenced oil and protein contents, possibly by regulating the transcription ofGmSWEET10a. Population genetic diversity analysis suggested that allelic variations ofGmST05were selected during geographical differentiation but have not been fixed. In summary, natural variation inGmST05determines transcription levels and influences seed size and quality in soybean, making it an important gene resource for soybean molecular breeding.
Risk factors and incidence of cytomegalovirus viremia and disease in pediatric patients with allogeneic hematopoietic stem cell transplantation: An 8‐year single‐center experience in Latin America
Authors: Aristizabal Ana M. , Perez Paola , Patiño Niño Jaime A. , Franco Alexis , Tarapues Eliana Manzi , Beltran Estefania , Medina Diego 
Published: June 2022

AbstractBackgroundCytomegalovirus infection represents a significant cause of morbidity and mortality after hematopoietic stem cell transplantation. This study aimed to evaluate the incidence of viremia and disease due to cytomegalovirus and the risk factors in pediatric patients with hematopoietic stem cell transplantation in our institution.MethodsThis was a retrospective cohort of patients under 19 years of age who underwent allogeneic hematopoietic stem cell transplantation due to any indication between 2012 and 2019. The analysis included the diagnosis of cytomegalovirus viremia or disease during post‐transplant follow‐up, evaluation of risk factors, and outcomes. The statistical analysis included univariate and multivariate analyses, and the cumulative incidence of cytomegalovirus viremia was determined by the Kaplan–Meier method using STATA 14 statistical software.ResultsA total of 182 transplants were included. At 100 days, the cumulative incidence of cytomegalovirus viremia was 70.5%, and that of cytomegalovirus disease was 4.7%. Overall survival at 2 years was 74%, and event‐free survival was 64%. The remaining demographic characteristics were not predictors of infection. There was no association between viremia and relapse or survival of the patients. Higher mortality was noted in cytomegalovirus disease.ConclusionsDuring the study period, the incidence of cytomegalovirus disease was similar to that of other pediatric reports, but the incidence of viremia was higher. Pre‐emptive therapy has diminished disease rates and death due to infection. Viral load cutoff points should be standardized to guide treatment and avoid myelotoxicity.
Executive leadership, policy tourism, and policy diffusion among local governments
Authors: Yi Hongtao , Liu Ivy 
Published: June 2022

AbstractPolicy tourism is an important but rarely studied phenomenon describing a widespread practice, through which local public and business leaders form delegations, choose target cities, and implement intercity policy diffusion, business exchange, and economic collaboration. Our research examines how executive leadership characteristics, city‐level contextual factors, and interdependence mechanisms relate to cities' decisions to visit. Using two‐stage probit selection models with instrumental variables on a dyadic balanced panel dataset recording all policy tourism events between major U.S. cities from 2007 to 2016, we answer this question accounting for potential endogeneity problems. Our findings suggest that cities with experienced yet newly appointed, minority leaders tend to visit cities with experienced white or female leaders. Additionally, policy tourism happens among cities embedded in highly complex, munificent, and turbulent environments. Finally, cities tend to learn from peers with higher economic prosperity or interact with their competitors.
Use of hepatitis B viremic donors in kidney transplant recipients: A single center experience
Authors: Carnemolla Brooke T. , Kutzler Heather L. , Kuzaro Hillary A. , Morgan Glyn , Serrano Oscar K. , Ye Xiaoyi , Cheema Faiqa 
Published: June 2022

AbstractUtilization of Hepatitis B virus (HBV)‐infected kidney allografts represents an opportunity to bridge the gap between organ supply and demand. Highly efficacious vaccines and antiviral therapies allow these allografts to be transplanted with negligible risk to the recipient. The purpose of this study was to describe the prophylactic strategies and related clinical outcomes of kidney transplant recipients who received a kidney from an HBV viremic donor. Eight patients received an allograft from an HBV viremic deceased kidney donor between January 1, 2017 and December 4, 2020. All recipients were immune to hepatitis B with a surface antibody titer greater than or equal to 10 mIU/ml (range: 12 ‐ > 1000 mIU/ml). After transplant, 62.5% demonstrated HBV core antibody seroconversion at an average of 47.4 ± 28.5 days post‐transplant. Anti‐viral prophylaxis was initiated in 87.5% of patients; 62.5% preemptively during the transplant admission (range 1–3 days post‐transplant) and 25% following HBcAb seroconversion (range 45–304 days post‐transplant). Of the four patients who were started on entecavir preemptively, two subsequently core converted. These two patients had an HBV surface antibody less than 100 mIU/ml at the time of transplant. None of the recipients converted to HBV surface antigen positivity. The average estimated glomerular filtration rate was 41 ± 19 ml/min/1.73m2, and there were no significant elevations in liver enzymes through one year post‐transplant. The use of HBV viremic kidney allografts may represent an additional source of transplant organs; however, more studies are needed to better elucidate the optimal protective strategies for these recipients.image
The evolution of extremely diverged plastomes in Selaginellaceae (lycophyte) is driven by repeat patterns and the underlying DNA maintenance machinery
Authors: Xiang Qiao‐Ping , Tang Jun‐Yong , Yu Ji‐Gao , Smith David Roy , Zhu Yan‐Mei , Wang Ya‐Rong , Kang Jong‐Soo , Yang Jie , Zhang Xian‐Chun 
Published: June 2022

SUMMARYTwo factors are proposed to account for the unusual features of organellar genomes: the disruptions of organelle‐targeted DNA replication, repair, and recombination (DNA‐RRR) systems in the nuclear genome and repetitive elements in organellar genomes. Little is known about how these factors affect organellar genome evolution. The deep‐branching vascular plant family Selaginellaceae is known to have a deficient DNA‐RRR system and convergently evolved organellar genomes. However, we found that the plastid genome (plastome) of Selaginella sinensis has extremely accelerated substitution rates, a low GC content, pervasive repeat elements, a dynamic network structure, and it lacks direct or inverted repeats. Unexpectedly, its organelle DNA‐RRR system is short of a plastid‐targeted Recombinase A1 (RecA1) and a mitochondrion‐targeted RecA3, in line with other explored Selaginella species. The plastome contains a large collection of short‐ and medium‐sized repeats. Given the absence of RecA1 surveillance, we propose that these repeats trigger illegitimate recombination, accelerated mutation rates, and structural instability. The correlations between repeat quantity and architectural complexity in the Selaginella plastomes support these conclusions. We, therefore, hypothesize that the interplay of the deficient DNA‐RRR system and the high repeat content has led to the extraordinary divergence of the S. sinensis plastome. Our study not only sheds new light on the mechanism of plastome divergence by emphasizing the power of cytonuclear integration, but it also reconciles the longstanding contradiction on the effects of DNA‐RRR system disruption on genome structure evolution.
Rolling Bearing Damage Evaluation by the Dynamic Process From Self-Induced Resonance to System Resonance of a Duffing System
Authors: Zhang Shuai , Wang Zhongqiu , Yang Jianhua 
Published: June 2022

Abstract
The dynamic response of a Duffing system from self-induced resonance to system resonance is studied in this paper. From numerical simulation, it is found that the system response gradually transits from self-induced resonance to system resonance with the increase of the pulse amplitude of the signal. In order to describe this process, we define the quality factor of the system response. With the evolution from self-induced resonance to system resonance, the quality factor gradually increases from 0 to 1. Then, based on the evolution, a novel method is developed to evaluate the severity of rolling bearing early damage. The results show that the method can be used not only to describe the process of a rolling bearing from healthy to damaged, but also to evaluate the severity of the early damage of a rolling bearing. The quality factor is a key index to reflect the severity of a rolling bearing. In addition, the sensitivity of the quality factor is superior to other traditional indices formerly used in the early damage evaluation. The effective method gives a new way for rolling bearing early damage evaluation.
Hybrid Monte Carlo-Diffusion Studies of Modeling Self-Heating in Ballistic-Diffusive Regime for Gallium Nitride HEMTs
Authors: Li Han-Ling , Shen Yang , Hua Yu-Chao , Sobolev S. L. , Cao Bing-Yang 
Published: June 2022

Abstract
Exact assessment of self-heating is of great importance to the thermal management of electronic devices, especially when completely considering the cross-scale heat conduction process. The existing simulation methods are either based on convectional Fourier's law or limited to small system sizes, making it difficult to deal with noncontinuum thermal transport efficiently. In this paper, a hybrid phonon Monte Carlo diffusion method is adopted to predict device temperature in ballistic–diffusive regime. Heat conduction around the heat generation region and boundaries are simulated by phonon Monte Carlo (MC) method, while the other domain is by Fourier's law. The temperature of the hybrid method is higher than that of Fourier's law owing to phonon ballistic transport, and the calculation efficiency of the hybrid method is remarkably improved compared with phonon MC simulation. Furthermore, the simulation results indicate that the way of modeling self-heating has a remarkable impact on phonon transport. The junction temperature of the heat source (HS) scheme can be larger than that of the heat flux (HF) scheme, which is opposite to the result under Fourier's law. In the HS scheme, the enhanced phonon-boundary scattering counteracts the broadening of the heat source, leading to a stronger ballistic effect and higher temperatures. The conclusion is verified by a one-dimensional analytical model. This work has opened up an opportunity for the fast and extensive thermal simulations of cross-scale heat transfer in electronic devices and highlighted the influence of heating schemes.
Modeling the Performance of Fuzzy Expert System for Prediction of Combustion, Engine Performance, and Exhaust Emission Parameters of a Spark Ignition Engine Fueled With Waste Bread Bioethanol-Gasoline Blends
Authors: Yasar Ali , Kul Bahar Sayin , Ciniviz Murat 
Published: June 2022

Abstract
This article focuses on the use of a rule-based Mamdani-type fuzzy expert system for the prediction of Pmax, HRRmax, ID, and CD as combustion parameters, BTE and BSFC as engine performance parameters, and CO, CO2, HC, and NOx as exhaust emission parameters of fuel blends formed by blending waste bread bioethanol with gasoline in different proportions. For modeling of 55 test conditions created by being operated test engine with 11 different test fuels under five different engine loads. As a result of the study, while combustion parameters were predicted with correlation coefficients in the range of 0.948–0.973% for waste bread bioethanol-gasoline blends, correlation coefficients for engine performance and exhaust emission parameters were in the range of 0.968–0.977% and 0.955–0.991% respectively. Similarly, the ranges of correlation coefficients obtained for sugar beet bioethanol-gasoline blends with fuzzy expert system were as follows: 0.967–0.971% for engine performance parameters, 0.955–0.978% for exhaust emission parameters, and 0.951–0.964% for combustion parameters. These results prove that costly and labor-intensive engine tests can be predicted with minimum effort and high accuracy with the developed model.
A Novel Trajectory-Based Mechanistic Model for Predicting Solid Particle Erosion in Elbows
Authors: Darihaki Farzin , Zhang Jun , Shirazi Siamack A. , McLaury Brenton S. 
Published: June 2022

Abstract
Solid particle erosion is a common and challenging phenomenon during the production and transport of particle-containing fluids and it is important to have models for predicting erosion rates accurately, especially for geometries such as elbows. Mechanistic models aim at predicting erosion accurately with low computational cost. In this study, a new particle trajectories-based mechanistic model is proposed to address the issues of liquid-dominated flows and the effect of particle size. Detailed flow and particle information for a standard elbow with water and air and different particle sizes are extracted from computational fluid dynamics (CFD) and analyzed to obtain a representative trajectory. The developed model includes various components that are sensitive to the particle size and flow conditions and accounts for the angle of impact and the turbulence in the flow. The proposed model is examined against CFD predictions for different pipe and particle sizes, and velocities with air, water, high-pressure air, and high-viscosity liquid. In comparison to an available mechanistic model, the new model provides relatively lower errors in predicting maximum erosion for many flow conditions. Moreover, the proposed model is found to be more consistent with CFD data for high-pressure air and higher-viscosity liquids. The model is further validated with experimental data for various conditions. Comparisons against numerical and experimental data suggest that the proposed model provides a significant improvement for liquid–solid flows and small particles.
Experimental Study on Water-Plugging Performance of Silicon Dioxide/Polystyrene Hydrophobic Insoluble Microsphere Particle Flooded by High-Water-Cut Oil–Water Mixture
Authors: Zheng Liming , Wang Hao , Zhang Yangyang , Wang Yu , Li Yanlin 
Published: June 2022

Abstract
Water plugging was an important but difficult process close to high-water-cut production wells. The injected water-plugging materials were usually liquid and typically had been evaluated by conventional water-flooding experiments. In this study, silicon dioxide (SiO2)/polystyrene hydrophobic insoluble microsphere particles were introduced as a selective water shutoff agent, and the water-saturated core was flooded with a high-water-cut oil–water mixture. Indexes such as modified oil-coning time, water-cut fluctuation, and cumulative water cut were proposed to evaluate water-plugging capability. A parametric study was conducted to evaluate the influence of particle composition (A, SiO2/polystyrene particle; B, complete polystyrene particle), water cut of the injected oil–water mixture, and preheating temperature of the insoluble particles on water-plugging performance. The results from the index analysis and relative permeability curve showed that the proposed indexes could be used to compare water-plugging performance during oil–water mixture drive; both particles had better water-plugging performance when the injected mixture was not an ultrahigh water cut (fw &lt; 90%). Particle B had larger lipophilicity and stronger capacity for decreasing the water cut (about 0.55–1.28%) at a conventional temperature when the oil–water mixture of the injected fluid had a water cut of 90%. Particle A had lower capacity to decrease the water cut (by about −0.94–0.26%), but it was resistant to reservoir temperature because of its dense structure and the addition of SiO2. These results provided suggestions for the application of hydrophobic insoluble microsphere particles in water plugging in production wells.
Initial Maximum Push-Rim Propulsion and Sprint Performance in Elite Women’s Wheelchair Basketball: Differences Between Players’ Functional Classification
Authors: García-Fresneda Adrián , Carmona Gerard , Yanci Javier , Iturricastillo Aitor 
Published: June 2022

The aim of the present study was to determine, for the first time in elite women’s wheelchair basketball, the differences in the initial maximum push-rim propulsion (IMPRP), mechanical outputs, and sprint performance between A category (≤2.5 class) and B category (≥3 class) players. A secondary aim was to assess the association between IMPRP mechanical outputs and sprint performance to determine the influence of specific strength in the latter. Sixteen Spanish women’s wheelchair basketball players participated in this study: A category (n = 9, International Wheelchair Basketball Federation [IWBF] classification range: 1–2.5 points) and B category (n = 7, IWBF classification range: 3–4.5 points). All the players undertook 2 tests: the IMPRP test to measure the strength variables and the 3-, 5-, and 12-m sprint test. B category players reported significantly better performance values in almost all the IMPRP variables and all the sprint distances than A category players. Large to very large significant correlations were observed among IMPRP absolute mechanical outputs (excepting mean power) and sprint performance (3, 5, and 12 m) for all the participants. When the group was divided according to categories A and B, the significant differences observed in the whole group decreased in both groups, although some relationships were large or very large. The IMPRP test and sprint test (3, 5, and 12 m) seemed to be sensitive to differentiate the level between the 2 functional categories. In addition, there was a high association between strength and sprint variables, which shows that greater strength could improve sprint capacity.
Increase in Bruch’s membrane opening minimum rim width with age in healthy children: the Hong Kong Children Eye Study
Authors: Zhang Xiu Juan , Tang Shu Min , Wang Yu Meng , Zhang Yuzhou , Chan Hei-Nga , Lau Yi Han , Kam Ka Wai , Chan Poemen P , Ip Patrick , Young Alvin L , Tham Clement C , Chen Li Jia , Pang Chi Pui , Yam Jason C 
Published: June 2022

Background/aimsTo identify normative values and determinants for Bruch’s membrane opening (BMO) and the minimum rim width of BMO (BMO-MRW) among healthy children.MethodsA population-based cross-sectional study from the Hong Kong Children Eye Study, recruiting 1, 226 children aged 6–8 years. Spherical refractive error, axial length (AL), body mass index and intraocular pressure (IOP) were measured. The optic nerve head and the peripapillary retinal nerve fibre layer (p-RNFL) were imaged through spectral domain-optical coherence tomography, using 24 equally spaced radial B-scans. Global and sectoral BMO-MRW values, BMO area and fovea-to-BMO (FoBMO) angle were calculated. Multiple regression analysis was performed to define the determinants of BMO area and BMO-MRW in relation to demographic and ocular parameters.ResultsThe mean values for global BMO-MRW, BMO area and FoBMO angle among children were 345.76±54.08 µm, 2.34±0.49 mm2and −5.45±4.36°, respectively. Global and sectoral values for BMO-MRW correlated with p-RNFL thickness (r=0.11–0.35, p<0.001). After adjusting for demographic and ocular parameters, global BMO-MRW increased with age (β=6.4, p<0.001) and greater global p-RNFL thickness (β=1.41, p<0.001), but decreased with larger BMO area (β=−47.46, p<0.001) and higher IOP (β=−1.73, p<0.001). Global BMO-MRW did not associate with AL, whereas both BMO area and FoBMO angle associated with AL (β=0.04, p=0.02 and β=0.31, p=0.03, respectively), but not with age.ConclusionWe observed that BMO-MRW increases with age among children. Our results provide normative values and the determinants of BMO parameters among Chinese children.