bluuebunny/crossref_metadata_2025_split huggingface dataset:
Atmospheric Boundary Layers over an Oceanic Eddy
Authors: Sullivan Peter P. , McWilliams James C. 
Published: October 2022

Abstract
Imagery and numerical modeling show an abundance of submesoscale oceanic eddies in the upper ocean. Large-eddy simulation (LES) is used to elucidate eddy impacts on the atmospheric boundary layer (ABL) forced by winds, convection, and an eddy with varying radius; the maximum azimuthal eddy speed is 1 m s−1. Simulations span the unstable regime −1/L = [0, ∞], where L is the Monin–Obukhov (M–O) stability parameter. A linearized Ekman model and the LES couple ABL winds to an eddy through rough-wall M–O boundary conditions. The eddy currents cause a surface stress anomaly that induces Ekman pumping in a dipole horizontal pattern. The dipole is understood as a consequence of surface winds aligned or opposing surface currents. In free convection a vigorous updraft is found above the eddy center and persists over the ABL depth. Heterogeneity in surface temperature flux is responsible for the full ABL impact. With winds and convection, current stress coupling generates a dipole in surface temperature flux even with constant sea surface temperature. Wind, pressure, and temperature anomalies are sensitive to an eddy under light winds. The eddy impact on ABL secondary circulations is on the order of the convective velocity scale but grows with increasing current speed, decreasing wind, or increasing convection. Flow past an isolated eddy develops a coherent ABL “wake” and secondary circulations for at least five eddy radii downwind. Kinetic energy exchanges by wind work indicate an eddy-killing effect on the oceanic eddy current, but only a spatial rearrangement of the atmospheric wind work.
Comparison of Nasal Obstruction Symptom Evaluation Score Outcomes After Autologous Cartilage Grafts and Latera Nasal Implants
Authors: Clark Christine M. , Hakimi Amir A. , Parsa Keon M. , Tanenbaum Zachary , Wang Haijun , Chu Eugenia , Reilly Michael J. 
Published: October 2022

Objective: To compare quantitative Nasal Obstruction Symptom Evaluation (NOSE) scores for ACG and Latera implants for nasal valve repair. Methods: Retrospective chart review of patients who underwent ACG or Latera placement between January 2016 through May 2019 by a single surgeon. Patients who had completed NOSE surveys pre- and post-operatively were identified and eligible for inclusion. Data regarding baseline demographic characteristics, adjunctive surgical procedures, NOSE scores at 1, 3, and 6-month post-operative visits, complications, and total operative time were collected. Unpaired t-tests and linear mixed models were performed to analyze differences between study groups. Results: There were 24 and 39 patients who underwent ACG and Latera, respectively, who met eligibility criteria. There were no differences in demographic characteristics or pre-operative baseline NOSE scores (ACG: 65.1 and Latera: 64.4; P = .92) between groups. Mean operative times were not significantly different between groups (ACG: 113 minutes and Latera: 102 minutes; P = .76). Within each group, NOSE scores were significantly improved at each post-operative visit compared to pre-operative baselines. Between groups, mean NOSE scores were lower at each post-operative visit for ACG compared to Latera (1-month ACG: 21.7 and Latera: 45.9, P = .002 ; 3-month ACG: 14.5 and Latera: 39.9, P = .034; 6-month ACG: 8.4 and Latera: 44.2, P = .003). Conclusions: Both ACG and Latera offer significant improvements in patient-reported nasal obstruction severity; however, ACG may yield more favorable subjective symptom scores.
Lessons learned from a gender-specific educational programme supporting young women with experience of domestic abuse
Authors: Warwick-Booth Louise , Coan Susan 
Published: October 2022

Background: Domestic abuse is a public health issue, and increasing evidence suggests that young women are more likely to suffer than older women, yet limited evidence exists in England about educational and intervention programmes for young women at risk. Study’s objectives: To evaluate a gender-specific (women-only) programme aimed at educating young women aged 13–25 years about abuse and staying safe in one English city. Setting: A third sector (charitable) organisation, aiming to improve women’s health in one English city delivered the programme over a 3-year period, funded by the Big Lottery Fund. Young women received both peer and one-to-one support, to educationally inform them, develop their skills and improve their capabilities in responding to abuse. Method: This qualitative evaluation captured the perspectives of young women accessing the programme ( n = 33), exploring the positive difference that it made to their lives. We also captured the views of internal stakeholders in 2018 ( n = 2), then followed up in 2020 ( n = 3), and external stakeholders referring young women to the programme ( n = 8). Results: The programme met its aims. Self-reported changes in young women’s lives included increased knowledge about staying safe and being happier. Some young women gained or retained custody of their children, and others exited harmful relationships. Young women identified a range of mechanisms of success including a non-judgemental approach from workers, peer support and a trusted space in which to meet and learn. The programme increased young women’s skills to stay safe while improving their mental wellbeing. Conclusion: The programme worked well for young women who accessed it. However, it could not reach all those in need, was only funded in the short-term and tended to individualise the responsibility for staying safe. Further research is needed in other community-based educational programmes to provide evidence of their effectiveness as well as transferrable models for workers in other contexts.
Toward smart composites: Small-scale, untethered prediction and control for soft sensor/actuator systems
Authors: Manzano Sarah A , Sundaram Vani , Xu Artemis , Ly Khoi , Rentschler Mark , Shepherd Robert , Correll Nikolaus 
Published: October 2022

We present formulation and open-source tools to achieve in-material model predictive control of sensor/actuator systems using learned forward kinematics and on-device computation. Microcontroller units that compute the prediction and control task while colocated with the sensors and actuators enable in-material untethered behaviors. In this approach, small parameter size neural network models learn forward kinematics offline. Our open-source compiler, nn4mc, generates code to offload these predictions onto MCUs. A Newton-Raphson solver then computes the control input in real time. We first benchmark this nonlinear control approach against a PID controller on a mass-spring-damper simulation. We then study experimental results on two experimental rigs with different sensing, actuation and computational hardware: a tendon-based platform with embedded LightLace sensors and a HASEL-based platform with magnetic sensors. Experimental results indicate effective high-bandwidth tracking of reference paths (≥120 Hz) with a small memory footprint (≤6.4% of flash memory). The measured path following error does not exceed 2mm in the tendon-based platform. The simulated path following error does not exceed 1mm in the HASEL-based platform. The mean power consumption of this approach in an ARM Cortex-M4f device is 45.4 mW. This control approach is also compatible with Tensorflow Lite models and equivalent on-device code. In-material intelligence enables a new class of composites that infuse autonomy into structures and systems with refined artificial proprioception.
Prevalence, risk factors and effectiveness of falls prevention interventions for adults living with Mild Cognitive Impairment in the community: A systematic review and meta-analysis
Authors: Hopkins Jane , Hill Keith , Jacques Angela , Burton Elissa 
Published: October 2022

Objectives To identify falls prevalence, falls risk factors and evaluate the effectiveness of falls prevention interventions for community-dwelling people with Mild Cognitive Impairment. Data sources Peer-reviewed articles (inception to 4 August 2022) from PubMed, CINAHL, PsycInfo, EMBASE, Scopus, SportDiscus and the Cochrane library. Review methods All types of methodological approaches were considered. Inclusion criteria were community-dwelling; diagnosis of Mild Cognitive Impairment; aged 50+ years. Interventions needed to include falls prevention programs aiming to reduce falls and/or risk of falls. Outcomes of interest included number and/or rate of falls, falls prevalence and falls risk factors. For controlled trials, any control group was included. Quality assessment was completed using Cochrane's Risk of Bias Tool for randomized controlled trials and the Standard Quality Assessment Criteria for Evaluating Primary Research Papers from a Variety of Fields for all other studies. Where statistical data pooling was not possible, narrative synthesis was used to present data in tables and figures. Results Forty-seven studies were included. Prevalence of falls was 43% when data were gathered prospectively for 12 months. Confirmed falls risk factors included slow gait, dual-tasking, postural control and non-amnestic Mild Cognitive Impairment. Few studies evaluated interventions to reduce falls. Six meta-analyses were conducted, no significant reduction in falls was found. Conclusions Until further high-quality, adequately powered studies are available to guide practice, best practice guidelines recommend balance training as a core component of falls prevention programs for older people generally, as well as people with Mild Cognitive Impairment.
Impact of COVID-19 on the Prescribing Pattern of Oral Anticoagulants for Atrial Fibrillation After Cardiac Surgery
Authors: Brochu Dannick , St-Arnaud Amélie , Marchand Louis-Étienne , Voisine Pierre , Méthot Julie 
Published: October 2022

Background: Because of logistic challenges associated with the COVID-19 pandemic, direct oral anticoagulants (DOAC) were favored over warfarin in patients presenting postoperative atrial fibrillation (AF) after cardiac surgery in our institution. Considering the limited evidence supporting the use of DOAC in this context, we sought to evaluate the safety and efficacy of this practice change. Methods: A retrospective study was performed with patients from the Quebec City metropolitan area who were hospitalized at the Institut universitaire de cardiologie et de pneumologie de Québec-Université Laval following cardiac surgery and who required oral anticoagulant (OAC) for postoperative AF. The primary objective was to compare the pre- and peri-COVID-19 period for OAC prescribing patterns and the incidence of thrombotic and bleeding events at 3 months post-surgery. The secondary objective was to compare DOAC to warfarin in terms of thrombotic events and bleeding events. Results: A total of 233 patients were included, 142 from the pre-COVID-19 and 91 from the peri-COVID-19 period, respectively. Both groups had equivalent proportions of preoperative AF (48%) and new-onset postoperative AF (52%). The proportion of patients treated with a DOAC increased from 13% pre-COVID-19 to 82% peri-COVID-19. This change in practice was not associated with a significant difference in the incidence of thrombotic or bleeding events 3 months postoperatively. However, compared to DOAC, warfarin was associated with a higher incidence of major bleeding. Only 1 thrombotic event was reported with warfarin, and none were reported with DOAC. Conclusion: This study suggests that DOAC are an effective and safe alternative to warfarin to treat postoperative AF after cardiac surgery and that this practice can be safely maintained.
Pediatric language assessments via telehealth: A systematic review
Authors: Alfano Alliete R , Concepcion Iliana , Espinosa Ashley , Menendez Faviana 
Published: October 2022

Introduction Assessment is crucial in the identification of children with potential delays/disorders and allows speech-language pathologists the opportunity to provide early intervention when indicated. For this reason, inaccessibility to formal assessments can be detrimental to the development and progression of overall communication skills for children with language disorders. The COVID-19 pandemic highlighted the need for increased telehealth services and how the provision of these remote services offers a much-needed alternative to face-to-face services for both clinicians and families. Method A systematic procedure involving online literature searches in four electronic databases was employed to identify studies for inclusion in this review. Inclusion criteria were as follows: (1) preschool or elementary pediatric participants, and (2) involve the delivery of language-based assessments via telehealth. Additionally, the search was limited to studies written in English, dated 2010 and newer, and published in peer-reviewed journals. Results The results of the systematic review showed there was no significant difference between standard scores and behavioral ratings for both face-to-face and telehealth assessments. The studies reviewed determined that telehealth delivery was feasible and presented adequate reliability with high levels of agreement between assessment scores obtained via telehealth and face-to-face. Conclusion Current research suggests that there is no significant difference between remote and face-to-face assessment administration. Additional research is needed to examine the feasibility and reliability of conducting language-based assessments via telehealth in bilingual children, children younger than four years of age, and in different environments, such as schools or clinics.
An evaluation of intervention research for transition-age autistic youth
Authors: Bottema-Beutel Kristen , LaPoint Shannon Crowley , Kim So Yoon , Mohiuddin Sarah , Yu Qun , McKinnon Rachael 
Published: October 2022

In this systematic evaluation of intervention research for transition-age autistic youth, we examined quality indicators in 193 group and single-case design intervention studies, which tested effects on 1258 outcomes. Behaviorally based interventions were the most common intervention type. We found significant threats to internal validity for the majority of studies, including inadequate randomization, unmasked assessors, and too few data points to infer functional relations. The majority of outcomes were measured in contexts similar to the intervention and were conceptualized as behaviors directly addressed by intervention procedures. As such, they are of unclear long-term utility for autistic people entering adulthood. Adverse events were rarely reported. We suggest several avenues for improving intervention research for this age group. Lay abstract In this study, we assess the quality of intervention research that focuses on autistic youth who are 14–22 years old. We found 193 different studies on this topic, and carefully reviewed them. Most of these studies tested strategies that were behavioral. This means that they used procedures like prompting and rewards to change participants’ behavior. We found that the majority of studies had problems that make it hard to determine whether or not the intervention worked. The problems related to how researchers designed their studies, and how they measured the study outcomes. We also found that researchers rarely tried to find out if the strategies they studied had unintended negative effects for participants. Because of these issues, we make suggestions for how researchers might design better studies that will let people know how well the strategies worked.
Lifestyle Medicine: An Antidote to Cardiovascular Diseases
Authors: Reddy Koushik R. , Freeman Andrew M. 
Published: October 2022

Despite numerous advances in basic understanding of cardiovascular disease pathophysiology, pharmacology, therapeutic procedures, and systems improvement, there hasn’t been much decline in heart disease related mortality in the US since 2010. Hypertension and diet induced risk continue to be the leading causes of cardiovascular morbidity. Even with the excessive mortality associated with the COVID-19 pandemic, in 2020, heart disease remained the leading cause of death. Given the degree of disease burden, morbidity, and mortality, there is an urgent need to redirect medical professionals’ focus towards prevention through simple and cost effective lifestyle strategies. However, current practice paradigm and financial compensation systems are mainly centered disease management and not health promotion. For example, the financial value placed on 3–10 min smoking cessation counseling (.24RVUs) is 47-fold lower than an elective PCI (11.21 RVUs). The medical community seems to be enamored with the latest and greatest technology, new devices, and surgical procedures. What if the greatest technology of all was simply the way we live every day? Perhaps when this notion is known by enough, we will switch to this lifestyle medicine technology to prevent disease in the first place.
Anti-inflammatory activity of ingredients from the heartwood of Vietnamese Dalbergia oliveri Gamble ex Prain
Authors: Nhan Ngu Truong , Nguyen Phi Hung , Hanh Dam Thi Bich , My Dang Thi Thuy , Nguyen Nguyen Phuong Dai , Phong Truong Ba , Huong Nguyen Thi Mai , Tran Manh Hung , Tram Nguyen Thị Thu , To Dao Cuong 
Published: October 2022

Objectives: To investigate the phytochemical constituents of Vietnamese Dalbergia oliveri and their inhibition of NO production. Methods: The ethyl acetate soluble fraction was subjected to column chromatography using silica gel and Sephadex LH-20 to isolate compounds. The chemical structures of isolated compounds were identified by nuclear magnetic resonance data and comparison with previously reported literature. The anti-inflammation effects of the isolated compounds on the lipopolysaccharide (LPS)-induced NO production in RAW 264.7 cells were measured using the Griess reaction. Results: Nine secondary metabolites (1−9) were isolated successfully from the heartwood of D. oliveri. The chemical structures of these compounds were identified as daidzein (1), formononetin (2), 3,7-dihydroxy-4′-methoxyflavone (3), liquiritigenin (4), 3′-methoxydaidzein (5), dalbergin (6), butin (7), sativanone (8), and isoliquiritigenin (9). This is the first time that compounds 1, 3, 5−8 have been isolated from D. oliveri. In the NO production inhibition, compounds 7 and 9 exhibited the most potent inhibitory activity, with IC50 values of 7.6 and 11.2 μM, respectively, followed by 3−6, with IC50 values from 19.6 to 28.7 μM. Conclusion: The results suggested that D. oliveri and its natural products might exert anti-inflammatory effects due to their NO-inhibiting actions.
A case of initially metastasizing pleomorphic adenoma of parotid gland
Authors: Ko Sungchul , Park Kye Hoon , Lee Ji-Hye , Park Ki Nam 
Published: October 2022

Metastasis of pleomorphic adenoma (PA) is rare and usually presented as a locoregional recurrence developed many years after excision of the primary tumor although the PA is the most common neoplasm in the parotid gland. We described a case of a 48-year-old male with a parotid tumor with multiple enlarged ipsilateral lymph nodes which suggested a malignancy. The tumors had been neither evaluated nor excised and preoperative evaluation revealed benign PA in both lesions. After the complete surgical excision, the final pathology was notable for benign PA with metastasis to regional lymph nodes. At 1 year follow up he was clinically and radiographically free of disease. This implies that pleomorphic adenoma can occur as initially metastasis to regional lymph node even though benign neoplasm.
Prevention of mother-to-child transmission screening among pregnant women in southern Ethiopia from the perspective of the current WHO recommendation
Authors: Dune Abebe , Rad Mulugeta Hailu , Wude Habtamu 
Published: October 2022

Objective: The aim of this study was to assess HIV screening for prevention of mother-to-child transmission service utilization and associated factors among pregnant women in Hadiya zone, Southern Ethiopia. Methods: The study was conducted in a community setting and was cross-sectional with a multistage sampling technique. A total of 613 women were selected randomly from 29 kebeles (the smallest administrative unit next to the district). Data were collected using a standardized interviewer-administered questionnaire. After being coded, reviewed, and entered into Epi-data, the data were exported to SPSS Version 21. Frequencies, percentages, graphs, and means and standard deviations were used to show descriptive data. In bivariate analysis, a p-value of 0.25 was utilized to identify candidate variables for multivariable logistic regression analysis. The statistical significance level was established at 0.05, and the strength of the association was measured using an adjusted odds ratio. Results: A total of 613 pregnant women out of 630 who were eligible, were included in our study. Among them, 276 (45%; 95% CI: 41.1–48.8) were tested for HIV. HIV screening was associated with secondary and higher maternal educational level (AOR = 5.01, 95% CI: (3.08–8.16)), number of antenatal care visits four and higher (AOR = 4.25, 95% CI: 2.41–7.51), distance from health facility (AOR = 1.93, 95% CI: 1.24–3.101), and male partner involvement (AOR = 1.88, 95% CI: 1.31–2.69). Conclusion: Less than half of the pregnant women included in our study had been tested for HIV; which was quite lower than the national requirement that every pregnant woman be tested during a visit. Only those who had a higher level of education, who regularly took antenatal care, who were not far away from the health facility, and whose partner was involved in antenatal care, were more susceptible to being tested. Thus, actions such as female education and increasing accessibility of the service should be prioritized.
Health workers’ experience of a digital health intervention implemented in peri-urban communities in Karachi, Pakistan
Authors: Haider Kaniz Amna , Gulam Omar , Adamjee Rehan , Balouch Benazir , Hoodbhoy Zahra 
Published: October 2022

Objective Digital health interventions (DHIs) have the potential to improve access and quality of care in low-middle-income countries. The aim of this study was to assess the acceptability, usability and aesthetics of a DHI by frontline workers in peri-urban community settings in Karachi, Pakistan. Methods A mixed-methods study was carried out in peri-urban field sites in Karachi, Pakistan, where maternal and childcare services are provided through front-line care providers using a DHI. These workers include community health workers, midwives, and physicians who were using the DHI for at least six months. For quantitative data, a questionnaire regarding the module design and interface, technical difficulty, and appropriate utilisation was assessed using a 5-point Likert scale. For qualitative data, focus group discussions (FGDs) based on experiences regarding operability, design, its effect on work efficiency and the provision of beneficial health services were conducted. Results There were 93 respondents for the quantitative questionnaire who reported high satisfaction (>85%) with the DHI in many themes including content quality, aesthetics and ease of use. Participants were least satisfied with service quality (45% satisfaction only) due to issues related to data sync and network connections in these areas. During the FGDs, the workers stated that the DHI helped them with accessing previous data and providing quality health care services to the community. Conclusion Although frontline workers reported a few technical difficulties while using the DHI, the majority reported that it was acceptable, had user-friendly features and was beneficial in their work processes.