bluuebunny/crossref_metadata_2025_split huggingface dataset:
Explicit smooth/nonsmooth cosimulation using kinematic constraints
Authors: Zhang Runsen , Zhang Huimin , Zanoni Andrea , Tasora Alessandro , Masarati Pierangelo 
Published: June 2022

AbstractAn explicit cosimulation scheme is developed to study the coupling of smooth and nonsmooth systems using kinematic constraints. Using the force-displacement decomposition, the coupling constraints are formulated at the velocity level, to preserve consistency with the impulse-momentum equations for frictional contacts in the nonsmooth solver, which however potentially leads to instability of the explicit cosimulation. To improve the stability of the cosimulation without affecting the format of the coupling constraints, guidelines for the modification of the prescribed motion are developed following the spirit of Baumgarte’s stabilization technique and the characteristics of the proposed integration scheme, which prescribes a combination of position, velocity, and acceleration to the constrained bodies. Using modified inputs, the stability of the cosimulation is tested using a rigidly connected two-mass oscillator model, which shows clear improvement compared to that with unaltered inputs. The performances of the cosimulation with modified inputs are further illustrated using a double-pendulum system and a complex flexible multibody system coupled with a particle damper. It follows that cosimulation results well agree with those obtained using monolithic simulation or simplified models, verifying the explicit smooth/nonsmooth cosimulation. The results also show a higher efficiency of the explicit cosimulation scheme, which requires much less computational time to obtain similar results, compared to the implicit smooth/nonsmooth cosimulation.
Prognostic utility of lncRNAs (LINC00565 and LINC00641) as molecular markers in glioblastoma multiforme (GBM)
Authors: Amer Rehab G. , Ezz El Arab Lobna R. , Abd El Ghany Dalia , Saad Amr S. , Bahie-Eldin Nermean , Swellam Menha 
Published: June 2022

Abstract
Background and aim
Glioblastoma multiforme (GBM) is primary brain tumor grade IV characterized by fast cell proliferation, high mortality and morbidity and most lethal gliomas. Molecular approaches underlying its pathogenesis and progression with diagnostic and prognostic value have been an area of interest. Long-non coding RNAs (lncRNAs) aberrantly expressed in GBM have been recently studied. The aim is to investigate the clinical role of lncRNA565 and lncRNA641 in GBM patients.

Patients and methods
Blood samples were withdrawn from 35 newly diagnosed GBM cases with 15 healthy individuals, then lncRNA565 and lncRNA641 expression were evaluated using real time-PCR. Their diagnostic efficacy was detected using receiver operating characteristic curve. Progression free survival (PFS) and overall survival (OS) were studied using Kaplan–Meier curves.

Results
lncRNAs expressions were increased significantly among GBM as compared to control group. Their expressions were correlated with clinico-pathological data and survival pattern for the studied GBM patients. Higher levels of both lncRNAs were correlated to worse performance status. Expression of lncRNA565 was increased with large tumor size (≥ 5 cm). Survival analysis showed that both investigated lncRNA were increased with worse PFS and OS.

Conclusion
Expression of lncRNA565 and lncRNA641 in a liquid biopsy sample can be used as prognostic biomarker for GBM patients.
On the sensitivity of implementations of a least-squares collocation method for linear higher-index differential-algebraic equations
Authors: Hanke Michael 
Published: June 2022

AbstractThe present paper continues our investigation of an implementation of a least-squares collocation method for higher-index differential-algebraic equations. In earlier papers, we were able to substantiate the choice of basis functions and collocation points for a robust implementation as well as algorithms for the solution of the discrete system. The present paper is devoted to an analytic estimation of condition numbers for different components of an implementation. We present error estimations, which show the sources for the different errors.
From Mask to Flesh and Back: A Semiotic Analysis of the Actor’s Face Between Theatre and Cinema
Authors: Beato Massimo Roberto 
Published: June 2022

AbstractWe aim to focus on the mimic gestures intentionally produced to be “monstrate” to others (expressive gestures), thus attempting to propose a semiotic analysis on the actor’s face. We shall attempt to outline the extent to which, (i) since the rise of cinema, the actor’s face has gained a foreground role as compared to the full-figured body, and (ii) the legacy of the nineteenth-century handbooks of scenic postures was crucial in this context, especially those of Antonio Morrocchesi and Alemanno Morelli. To deal with the actor’s body as an instrument, means to make it a blank page to be used to re-design the character’s body, including the face. In this regard, it is worth mentioning the method of the pedagogue Jacques Lecoq—one of the greatest teachers of contemporary theatre—which consists in the use of a special mask during the training process: the so-called neutral mask.
Boswellic acids ameliorate neurodegeneration induced by AlCl3: the implication of Wnt/β-catenin pathway
Authors: Mohamed Eman A. , Ahmed Hebatalla I. , Zaky Heba S. , Badr Amira M. 
Published: June 2022

AbstractAlzheimer’s disease (AD) is a neurodegenerative disease (ND) that represents the principal cause of dementia. Effective treatment is still lacking. Without prevention, Alzheimer’s disease (AD) incidence is expected to triple within 30 years. The risk increases in highly polluted areas and is positively linked to chronic aluminum (Al) exposure. Canonical Wingless-Int (Wnt)/β-catenin pathway has been found to play a considerable role in ND pathogenesis. Resins ofBoswellia serrata (frankincense) have been used traditionally for their psychoactive activity, in addition to their memory-boosting effects. Boswellic acids (BA) are pentacyclic triterpenes. They have antioxidant, anti-inflammatory, antinociceptive, and immunomodulatory activities. This study aimed to elucidate the role of the Wnt/β-catenin pathway in BA protective activity against aluminum-induced Alzheimer’s disease. For 6 weeks, rats were treated daily with AlCl3 (100 mg/kg/i.p.) either alone or with BA (125 or 250 mg/kg PO). Results indicated that BA significantly improved learning and memory impairments induced by AlCl3treatment. Moreover, BA treatment significantly decreased acetylcholinesterase levels and reduced amyloid-beta (Aβ) expression. In addition, BA ameliorated the increased expression of tumor necrosis factor-alpha (TNF-α) and interleukin-1 beta (IL-1β), inhibited lipid peroxidation, and increased total antioxidants in the brain. Indeed, BA significantly suppressed AlCl3-induced decrease of brain-derived neurotrophic factor, pGSK-3β (Ser 9), and β-catenin. BA (250 mg/kg) showed a significant protective effect compared to a lower dose. The results conclude that BA administration modulated the expression of Wnt/β-catenin pathway-related parameters, contributing to BA’s role against Al-induced Alzheimer’s disease.Graphical abstractEffect of Boswellic acids on AlCl3-induced neurodegenerative changes. ChE cholinesterase, Ach acetylcholine, BDNF brain-derived neurotrophic factor, IL-1β interleukin-1β, TNF-α tumor necrosis factor-α
Spillover dynamics effects between risk-neutral equity and Treasury volatilities
Authors: González-Urteaga Ana , Nieto Belén , Rubio Gonzalo 
Published: June 2022

AbstractMacro-finance asset pricing models provide a rationale for connectedness dynamics between equity and Treasury risk-neutral volatilities. In this paper, we study the total and directional connectedness, in the sense of spillover effects, between risk-neutral volatilities from the equity and Treasury markets. In addition, we analyze the economic and monetary drivers of connectedness dynamics. Most of the time, but especially during bad economic times, we find significant net spillovers from Treasury to equity risk-neutral volatility. The spillover channel between risk-neutral volatilities arises mainly through the government fixed income market.
Literacy education for citizenship across the lifespan
Authors: Farrell Lesley , Eadie Tricia , McLean Davies Larissa , Sandiford Carmel 
Published: June 2022

AbstractThe task of English language and literacy education to define citizenship, and shape citizens, has rarely been more compelling or more challenging than it is today. Globally and nationally, our civic response to COVID-19 has catapulted us into a world where our rights as and responsibilities as citizens are being fundamentally re-negotiated at the same time as we come to rely on technologically mediated literate practice to connect a world that is more spatially and temporally separated than many of us have ever known it to be. We are challenged to remake our identities and commit to new kinds of personal and civic relationships—nationally and globally—as we try to navigate uncharted waters. Our focus here is on the role that literacy education plays in understanding and defining active citizenship in a turbulent context in which foundational literacy practices are transforming just as accepted understandings of active citizenship are under challenge. We direct our attention specifically to the distinctive role that literacy practice plays in the production of identities and relationships and consider new ways for literacy education to build active citizenship across the lifespan from early education through primary and secondary education through to workforce education.
Social media data analysis framework for disaster response
Authors: Ponce-López Víctor , Spataru Catalina 
Published: June 2022

AbstractThis paper presents a social media data analysis framework applied to multiple datasets. The method developed uses machine learning classifiers, where filtering binary classifiers based on deep bidirectional neural networks are trained on benchmark datasets of disaster responses for earthquakes and floods and extreme flood events. The classifiers consist of learning from discrete handcrafted features and fine-tuning approaches using deep bidirectional Transformer neural networks on these disaster response datasets. With the development of the multiclass classification approach, we compare the state-of-the-art results in one of the benchmark datasets containing the largest number of disaster-related categories. The multiclass classification approaches developed in this research with support vector machines provide a precision of 0.83 and 0.79 compared to Bernoulli naïve Bayes, which are 0.59 and 0.76, and multinomial naïve Bayes, which are 0.79 and 0.91, respectively. The binary classification methods based on the MDRM dataset show a higher precision with deep learning methods (DistilBERT) than BoW and TF-IDF, while in the case of UnifiedCEHMET dataset show a high performance for accuracy with the deep learning method in terms of severity, with a precision of 0.92 compared to BoW and TF-IDF method which has a precision of 0.68 and 0.70, respectively.
Moment-constrained optimal dividends: precommitment and consistent planning
Authors: Christensen Sören , Lindensjö Kristoffer 
Published: June 2022

AbstractA moment constraint that limits the number of dividends in an optimal dividend problem is suggested. This leads to a new type of time-inconsistent stochastic impulse control problem. First, the optimal solution in the precommitment sense is derived. Second, the problem is formulated as an intrapersonal sequential dynamic game in line with Strotz’s consistent planning. In particular, the notions of pure dividend strategies and a (strong) subgame-perfect Nash equilibrium are adapted. An equilibrium is derived using a smooth fit condition. The equilibrium is shown to be strong. The uncontrolled state process is a fairly general diffusion.
Nash equilibrium structure of Cox process Hotelling games
Authors: Anantharam Venkat , Baccelli François 
Published: June 2022

AbstractWe study an N-player game where a pure action of each player is to select a nonnegative function on a Polish space supporting a finite diffuse measure, subject to a finite constraint on the integral of the function. This function is used to define the intensity of a Poisson point process on the Polish space. The processes are independent over the players, and the value to a player is the measure of the union of her open Voronoi cells in the superposition point process. Under randomized strategies, the process of points of a player is thus a Cox process, and the nature of competition between the players is akin to that in Hotelling competition games. We characterize when such a game admits Nash equilibria and prove that when a Nash equilibrium exists, it is unique and consists of pure strategies that are proportional in the same proportions as the total intensities. We give examples of such games where Nash equilibria do not exist. A better understanding of the criterion for the existence of Nash equilibria remains an intriguing open problem.
Non-invasive molecular biomarkers for predicting outcomes of micro-TESE in patients with idiopathic non-obstructive azoospermia
Authors: Tang Dongdong , Li Kuokuo , He Xiaojin , Zhang Yan , Cao Yunxia 
Published: June 2022

Abstract
Non-obstructive azoospermia (NOA), the most severe type of male infertility, affects approximately 1% of men worldwide. However, the aetiology of most NOA cases is not definite, that is defined as idiopathic NOA (INOA), posing a clinical conundrum worldwide. Most of these patients must receive donor sperm treatment until the emergence of microdissection testicular sperm extraction (micro-TESE). Although this procedure has recently become a promising treatment for INOA, the low sperm retrieval rate and testicular trauma have prompted us to explore appropriate non-invasive molecular biomarkers to predict the outcomes of sperm recovery preoperatively. Previous studies have identified a spectrum of biomarkers to address this challenging issue at various levels in different tissues, such as DNAs, RNAs, protein and steroid levels in the blood and seminal fluid. To better understand and assess the predictive values of diverse molecular biomarkers from different tissues on the outcome of sperm retrieval by micro-TESE in patients with INOA, we summarised recent findings and discussed the potential applications of these methods. The ultimate goal of this study was to provide references for further studies and clinical management.
Return-time -spectrum for equilibrium states with potentials of summable variation
Authors: ABADI M. , AMORIM V. , CHAZOTTES J.-R. , GALLO S. 
Published: June 2022

AbstractLet
$(X_k)_{k\geq 0}$
be a stationary and ergodic process with joint distribution
$\mu $
, where the random variables
$X_k$
take values in a finite set
$\mathcal {A}$
. Let
$R_n$
be the first time this process repeats its first n symbols of output. It is well known that
$({1}/{n})\log R_n$
converges almost surely to the entropy of the process. Refined properties of
$R_n$
(large deviations, multifractality, etc) are encoded in the return-time
$L^q$
-spectrum defined as provided the limit exists. We consider the case where
$(X_k)_{k\geq 0}$
is distributed according to the equilibrium state of a potential with summable variation, and we prove that where
$P((1-q)\varphi )$
is the topological pressure of
$(1-q)\varphi $
, the supremum is taken over all shift-invariant measures, and
$q_\varphi ^*$
is the unique solution of
$P((1-q)\varphi ) =\sup _\eta \int \varphi \,d\eta $
. Unexpectedly, this spectrum does not coincide with the
$L^q$
-spectrum of
$\mu _\varphi $
, which is
$P((1-q)\varphi )$
, and it does not coincide with the waiting-time
$L^q$
-spectrum in general. In fact, the return-time
$L^q$
-spectrum coincides with the waiting-time
$L^q$
-spectrum if and only if the equilibrium state of
$\varphi $
is the measure of maximal entropy. As a by-product, we also improve the large deviation asymptotics of
$({1}/{n})\log R_n$
.
Defining Rockefeller Republicanism: Promise and Peril at the Edge of the Liberal Consensus, 1958–1975
Authors: BARRETT MARSHA E. 
Published: June 2022

AbstractThis article examines Rockefeller Republicanism and its status within the Republican Party by looking at the evolution of Nelson Rockefeller’s support for social welfare policy between 1958 and 1975. New York Governor Nelson Rockefeller regularly appears in histories of modern conservatism as the embodiment of the liberalism that conservatives rejected, but these works rarely account for the entirety of Rockefeller’s career. Rather than focus on Rockefeller’s challenges to the national Republican Party in 1960 and 1964, which results in an incomplete representation of Rockefeller Republicanism, this article reassesses moderate Republicanism’s perceived dominance and Rockefeller’s advocacy for liberal domestic policies and commitment to racial liberalism in New York. A full account of Rockefeller’s struggles to find common ground with conservative New York Republicans and adoption of conservative positions related to law enforcement and welfare reform thwarted one of the GOP’s best opportunities to assemble a multiracial and cross-class constituency.
Insecurity and Self-Esteem: Elucidating the Psychological Foundations of Negative Attitudes toward Women
Authors: Mansell Jordan , Gatto Malu A. C. 
Published: June 2022

AbstractPolitical scientists recognize discriminatory attitudes as key to understanding a range of political preferences. Sexism is associated with both explicitly and non-explicitly gendered attitudes. But why do certain individuals display discriminatory attitudes, while others do not? Drawing from psychology, we examine the potential power of an underexplored set of personality traits—secure versus fragile self-esteem—in explaining gendered attitudes and preferences. With an online sample of (N = 487) U.S.-based participants, we find that fragile self-esteem is an important trait underlying individuals’ attitudes: individuals who display a discordant view of self—explicitly positive but implicitly negative—are more likely to hold hostile sexist attitudes and prefer men in leadership; these individuals are also more likely to support the Republican Party and former U.S. president Donald Trump. While present in only a fraction of the population, our results suggest that this trait may be important for understanding the development of discriminatory attitudes toward out-groups.
Validity of estimating center of pressure during walking and running with plantar load from a three-sensor wireless insole
Authors: Brindle Richard A. , Bleakley Chris M. , Taylor Jeffrey B. , Queen Robin M. , Ford Kevin R. 
Published: June 2022

Abstract
The purpose of this study was to determine if estimated center of pressure (COP) from plantar force data collected using three-sensor loadsol insoles was comparable to the COP from plantar pressure data collected using pedar insoles during walking and running. Ten healthy adults walked and ran at self-selected speeds on a treadmill while wearing both a loadsol and pedar insole in their right shoe. Plantar force recorded from the loadsol was used to estimate COP along mediolateral (COPx) and anteroposterior (COPy) axes. The estimated COPx and COPy were compared with the COPx and COPy from pedar using limits of agreement and Spearman’s rank correlation. There were significant relationships and agreement within 5 mm in COPx and 20 mm in COPy between loadsol and pedar at 20–40% of stance during walking and running. However, loadsol demonstrated biases of 7 mm in COPx and 10 mm in COPy compared to pedar near initial contact and toe-off.
Hybrid Simulations of a Tangential Discontinuity‐Driven Foreshock Bubble Formation in Comparison With a Hot Flow Anomaly Formation
Authors: Vu Andrew , Liu Terry Z. , Zhang Hui , Delamere Peter 
Published: June 2022

AbstractHot flow anomalies (HFAs) and foreshock bubbles (FBs) are significant foreshock transients that can accelerate particles and disturb the magnetosphere‐ionosphere system. Yet, their early formation mechanisms are still not fully understood. To investigate the formation of tangential discontinuity (TD)‐driven FBs and HFAs, we use 2‐D local hybrid simulations where a reflected or an injected warm foreshock ion beam can interact with a TD whose half‐thickness is comparable to the ion inertial scale. We show that the foreshock ions perform a partial gyration within, or across, the TD. Bulk motion differences between partially‐gyrating foreshock ions and fluid‐electrons lead to the generation of currents. As the trigger, these foreshock‐driven currents change the magnetic field topology around the TD and force the frozen‐in solar wind plasma to redistribute along with the field lines, shaping the foreshock transient. This confirms a recently proposed kinetic formation model. The extent of the magnetic field direction change across the TD within the foreshock ion gyromotion determines the current profile and thus the type of foreshock transient that forms. For a thin TD, the foreshock ions generate a current that is much stronger on the upstream side than the downstream side, forming an FB with one upstream compressional boundary. For the same foreshock ion gyroradius and magnetic shear, a thick TD yields comparable foreshock‐driven currents on the upstream and downstream sides, forming an HFA with two compressional boundaries. Our study suggests that the TD thickness is one of the factors that determine the formation of FBs and HFAs.
Two Techniques for Determining F‐Region Ion Velocities at Meso‐Scales: Differences and Impacts on Joule Heating
Authors: Kavanagh Andrew J. , Ogawa Yasunobu , Woodfield Emma E. 
Published: June 2022

AbstractWe have investigated the difference between two standard techniques for deriving the ionospheric ion velocity using data taken with the EISCAT incoherent scatter radar between 1987 and 2007. For large‐scale convection flows, there is little difference between the tristatic and monostatic techniques, though the biggest relative difference occurs during periods when the interplanetary magnetic field (IMF) is strongly northward. At small scales the difference between the two techniques is correlated with a measure of the variability of the tristatic measurement. This suggests that small‐scale flow bursts, such as those associated with enhanced auroral arcs, could explain the local time variation in the velocity difference distributions. The difference in velocities obtained from the monostatic and tristatic techniques can make a significant difference in the estimate of the magnitude of Joule heating in the thermosphere. Considering only the electric field dominated component of Joule heating, Q, the difference in the two techniques can be as much as 52% of the tristatic measurement (Qm = 0.48Qt) in the morning sector (0–6 MLT), during a moderate to large geomagnetic storm. This reduces to a difference of 36% at non‐storm times in the same MLT period. Careful averaging of the velocity field with the future EISCAT_3D radar system will allow us to establish the impact of both spatial and temporal scales on the magnitude of the observations.