bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Parameter Kecepatan Teoritik Dan Nilai Beda Fase Gelombang Rayleigh Lapisan Aspal Perkerasan Jalan Berdasarkan Teori Perambatan Gelombang Pada Media Yang Homogen Dan Isotropik
Authors: Rosyidi Sri Atmaja P 
Published: March 2022

The Rayleigh wave is one of seismic waves which generated from the natural and artificial mechanical source in the earth or place on the subsurface, such as landslide, earthquake, explosion, traffic vibration, machine works, etc. The Rayleigh wave in a possible stratified of homogeneous media is a linear combination of Primary (P) and Vertically Shear (SV) waves, which satisfied the equations of elasticity with zero body forces and zero traction on the boundary of a half-space media. In the case of a homogeneous isotropic half-space there is a unique mode of the Rayleigh waves which propagates without being sustained by any sources or external loads. Almost 70 % of wave energy generated from the mechanical sources is the Rayleigh wave energy. Therefore, it is a potential characteristic of Rayleigh wave that is able to be used in engineering purposes. One of them is a spectrum analysis that is applied in transportation engineering in order to control the quality of asphaltic material. The aim of this paper is to predict the Rayleigh wave velocity parameters and phase different value of asphaltic layer based on a fundamental theory of Rayleigh wave propagation in a homogeneous isotopic. The results have been shown that the phase different value in homogenous isotropic media is strongly influenced by field spacing of wave measurement. The Rayleigh wave velocity parameters were easier obtained using the simple equation considering to various Poisson value.
Surgical site infection outcomes of 2 different regimens for preoperative skin antisepsis: single layer with povidone-iodine versus double layer with povidone-iodine/ octenidine dihydrochloride
Authors: TURHAN Veysel Barış , TOPCU Ramazan , YILDIZ Alp 
Published: March 2022

Aim: Surgical site infection (SSI) is a frequent complication following any surgery. SSI still one of the main causes of elongated hospitalization, morbidity, and cost charges despite the development of new techniques, new materials, and new procedures. This study aims to compare the postoperative outcomes concerning single or double-layer or disinfectant application.
Material and Methods: This is a retrospective study aiming to inference the results of 2 different methods of preoperative skin disinfection after Lichtenstein tension-free open hernia repair with prolene mesh. A total of 298 patients enrolled in this study. This is a retrospective study comparing the outcomes of SSI open herniorrhaphy with prolene mesh.
Results: Wound infection has occurred in 13 patients from Group-1 (%6.80) versus 3 patients on Group-2 (%2.80) respectively, which is statistically significantly lower than Group-1(p˂0.05).
Conclusion: As our results showed, we suggest that octenidine dihydrochloride could be considered a powerful alternative to conventional disinfectant solutions, but further investigations with a single application of octenidine dihydrochloride are needed.
Prognostic value of left ventricular stroke work index in patients with advanced heart failure
Authors: YILDIZ Ömer , YENİGÜN Cemal 
Published: March 2022

Aim: The impact of reduced myocardial contractility on patients’ outcomes with advanced heart failure (HF) and the correct measurement units for its measure is most important. The present work aims to evaluate the prognostic value of the left ventricular stroke work index (LVSWI), which is considered a measure of myocardial contractility, in patients with advanced HF.
Material and Methods: Between September 2010 and July 2013, 172 patients with advanced HF admitted to the hospital to guide the specified therapies were included in this study. At baseline, patients were assessed with cardiac catheter-based hemodynamic measurements, ensued by the longitudinal follow-up (median of 52 months) for adverse outcomes (cardiac mortality, ventricular assist device (VAD) placement, and heart transplant (HTx)).
Results: Median LVSWI was 16 cJ/m2. Decreased LVSWI (
PROCESSES OF INNOVATION AND TECHNOLOGICAL APPROPRIATION IN COMMUNITY RADIO STATIONS. A STUDY OF LA COMETA AND LA ESQUINA RADIO IN COLOMBIA
Authors: Villa María Isabel , Triana Elluz Tatiana Pinilla , Rueda Lina María Alvarado 
Published: March 2022

The purpose of this research is to analyze the processes of social appropriation of the Information and Communication Technologies in the community radio stations La Cometa and La Esquina Radio located in Colombia. The qualitative analysis uses the semi-structured interview as a research method. The results of the study show how technology can strengthen the communicative projects of community radios, providing mobility, independence and facilitating their relationship and proximity to their communities of influence.
PROCESOS DE INNOVACIÓN Y APROPIACIÓN TÉCNOLÓGICA EN LAS EMISORAS COMUNITARIAS. UN ESTUDIO SOBRE LA COMETA Y LA ESQUINA RADIO EN COLOMBIA
Authors: Villa María , Triana Elluz Tatiana Pinilla , Rueda Lina María Alvarado 
Published: March 2022

En este artículo se analizan los procesos de apropiación social de las Tecnologías de la Información y la Comunicación en las emisoras comunitarias La Cometa y La Esquina Radio ubicadas en Colombia. El análisis de tipo cualitativo emplea como método de investigación la entrevista semiestructurada. Los resultados del estudio muestran como la tecnología puede fortalecer los proyectos comunicativos de las radios comunitarias, aportándoles movilidad, independencia y facilitando su relación y cercanía con sus comunidades de influencia.
Application of Quantitative Susceptibility Mapping in the Assessment of
Iron Content in Brain Regions of Normal Children
Authors: He Ling , Tang Shilong , Zhang Guanping , Liu Xianfan , Chen Zhuo 
Published: March 2022

Purpose:
We evaluated brain iron content in a healthy pediatric population using quantitative
susceptibility mapping (QSM).

Methods:
From June 2018 to December 2019, healthy subjects aged 2-18 years old (200 males, 200
females) with no anatomical abnormalities were assessed. All of the children underwent 3D T1 anatomical
MRIs in addition to the sequence scans of enhanced T2 star-weighted angiography (ESWAN).
The ESWAN sequence images were obtained with software to attain quantitative susceptibility mapping
of the entire brain. The magnetic susceptibility values in the same brain region were compared
across different age groups. The magnetic susceptibility values expressed in the same age group were
compared across sexes, brain sides, and brain regions.

Results:
The magnetic susceptibility value of each brain region increased with age, and the magnetic
susceptibility value expressed by each brain region demonstrated a positive correlation with the children’s
age (r=0.63, P<0.05). No dramatic difference in magnetic susceptibility was observed between
the brain’s left side and right side in the children within the age range ≥2-<6; however, among the children
within the age range ≥6-<18, the magnetic susceptibility values expressed by the left putamen
nucleus, globus pallidus, and substantia nigra were higher than those expressed by the same regions on
the right side (P<0.05).

Conclusion:
Quantitative susceptibility mapping can be used to evaluate the content of iron in each
brain region of normal children.

Clinical Trial registration:
This study protocol was registered at the Chinese clinical trial registry
(ChiCTR2000030656).
Synthesis Strategies and Medicinal Value of Pyrrole and its Fused
Heterocyclic Compounds
Authors: Fatahala Samar Said , Mohamed Mosaad Sayed , Sabry Jaqueline Youssef , Mansour Yara Esam El-Deen 
Published: March 2022

Abstract:
In the last several decades, interest in pyrrole and pyrrolopyrimidine derivatives has increased
owing to their biological importance, such as anti-tumor, anti-microbial, anti-inflammatory,
anti-diabetic, anti-histaminic, anti-malarial, anti-Parkinson, antioxidant and anti-viral effects, specially
recently against COVID-19. These tremendous biological features have motivated scientists to
discover more pyrrole and fused pyrrole derivatives, owing to the great importance of the pyrrole
nucleus as a pharmacophore in many drugs, and motivated us to present this article, highlighting on
the different synthetic pathways of pyrrole and its fused compounds, specially pyrrolopyrimidine, as
well as their medicinal value from 2017 till 2021.
Medicated Supportive Braces: A Synergy of Treatments for Joint Pain Relief
Authors: Limbasiya Dixita , Mehta Dharmik 
Published: March 2022

Background and objectives:
The present study unveils a simple but innovative combina-tion of existing treatments of three different domains with unique logical aspects. Joint pain is the major cause of disability, especially for older adults. Currently, two widely practiced treatment op-tions are combined to produce simultaneous treatments that overcome the drawbacks of individual treatment and improve patient compliance. Moreover, a third treatment option of cooling and coun-terirritant material (Menthol) for pain relief was also explored successfully as a substitute treatment.

Method:
In the present study, we formulated and optimized an adhesive topical patch of the model drug diclofenac sodium, a widely used medicine for pain relief and menthol, a cooling and counter-irritant substance to aid pain relief. Combinations of two polymers, PVP-K30 and PVA, selected by trial batches, were further optimized by applying a 3x2 full factorial design. Two factors, X1 (PVP-K30) and X2 (PVA), were optimized using three responses, R1 (Q2), R2 (Q4), and R3 (Q12). De-rived mathematical models for responses were validated using checkpoint batches. The final opti-mized batch was derived based on the desirability function. Factorial batches were also evaluated for relevant parameters.

Results:
Results obtained by checkpoint batches were in line with the experimental results with 5% relative error, revealing that the derived models were valid for the design. The final optimized batch obtained by the desirability function followed all set criteria. Medicated patch prepared by opti-mized formulation was incorporated into the knee brace using an in-house patch holder mechanism.

Conclutions:
Combined treatment offers better patient compliance for the patient and the healthcare provider, which can be extended to other pain-relieving supportive treatments like elbow braces, waist brace, back support belt, cervical brace, etc.
Piezoelectric Vibration Energy Harvesters with Distinct Interdigital Electrodes
Used for Toxic Gas Detection and in a Numerical Simulation for a
Glucose Sensor Application
Authors: Khrissi Salam , Lifi Houda , Lifi Mohamed , Nossir Naima , Tabbai Yassine , Hnawi Salma Kaotar 
Published: March 2022

Introduction:
In this paper, a surface acoustic wave sensor (SAW) for dangerous gas sensing applications has been designed and experimented. The Glucose Sensor applications has been simulated to show that the piezoelectric material has a high significance for use in detection.

Background:
Detection of gases is one of the major applications SAW gas sensor extend its services into the field of medical and even in power plants. A Surface Acoustic Wave (SAW) is an acoustic wave that propagates on the surface of an elastic material (usually a solid), with an amplitude that decreases with the depth of the substrate.

Objectives:
SAW devices typically use electrodes on a piezoelectric material to convert an electrical signal to a SAW.

Methods:
This paper reviews the significance of piezoelectric materials and focuses on MEMS based SAW, and we investigate the resonance frequencies of a SAW gas sensor, which consists of an Inter Digitated Transducer (IDT) etched onto a piezoelectric substrate and covered with a thin Poly Isobutylene (PIB) film.

Results:
The mass of the PIB film increases as PIB selectivity adsorbs CH2Cl2 (Dichloromethane, DCM) in the air. This causes a shift in resonance to a slightly lower frequency.

Conclutions:
Our characterization of the piezoelectric material have shown a high significance when a sensitive layer of gas is etch for detected the dangerous gases, we used it in another application Glucose Sensor to show the importance of our system. The sensor of the Glucose Gensor application has been designed and simulated by a finite element analysis which was conducted on LiNbO3 pellets. This model is applied to verify the sensing properties of DCM and the glucose. On the other hand, the Glucose Sensor and the toxic gas detection allow measurement of the concentration,whether it is for the dangerous gases or glucose. The concentration of external glucose and the current density versus glucose concentration were measured by a finite element.
Seeing Through the Walls with Wireless Technology: A Review
Authors: Verma Gautam , Sharma Dolly 
Published: March 2022

Background:
Wireless technology has made a great impact on the whole world by providing
us with 5G cellular to backscatter networking, from long-range wireless power to low-power
wide-area networks. The ability to see through the walls via wireless signals has ushered in a new era.
This technology has a wide range of applications, such as military, law enforcement, medicine, and
games.

Objective:
This paper has concisely analyzed recent advances in the field of see-through-the-wall
technology to improve a definitive knowledge of existing models and methodologies as well as provide
recommendations for future directions. One of the most recent models is the Xaver ™ LR80,
which is the first gadget that detects objects across a distance of more than 100 metres.

Methodology:
The dry lab technique for the comparison of existing models for frequency, power, model,
detection ability, accuracy, localization feature, and applications has been used. Further comparison is
based on the multipath effect. Their applications, the challenges that they need to face, and eventually
suggestions for future work have been elaborated.

Conclusion:
In general, the paper outlines the current level of knowledge in the field of see-through
the wall technology. It establishes a foundation for comprehending the issue by examining the findings
of contemporary research in the field.
Research Trends in Immune Checkpoint Blockade for Melanoma: Visualization and Bibliometric Analysis
Authors: Xu Yantao , Jiang Zixi , Kuang Xinwei , Chen Xiang , Liu Hong 
Published: March 2022

Background
Melanoma is one of the most life-threatening skin cancers; immune checkpoint blockade is widely used in the treatment of melanoma because of its remarkable efficacy.

Objective
This study aimed to conduct a comprehensive bibliometric analysis of research conducted in recent decades on immune checkpoint blockade for melanoma, while exploring research trends and public interest in this topic.

Methods
We summarized the articles in the Web of Science Core Collection on immune checkpoint blockade for melanoma in each year from 1999 to 2020. The R package bibliometrix was used for data extraction and visualization of the distribution of publication year and the top 10 core authors. Keyword citation burst analysis and cocitation networks were calculated with CiteSpace. A Gunn online world map was used to evaluate distribution by country and region. Ranking was performed using the Standard Competition Ranking method. Coauthorship analysis and co-occurrence were analyzed and visualized with VOSviewer.

Results
After removing duplicates, a total of 9169 publications were included. The distribution of publications by year showed that the number of publications rose sharply from 2015 onwards and either reached a peak in 2020 or has yet to reach a peak. The geographical distribution indicated that there was a large gap between the number of publications in the United States and other countries. The coauthorship analysis showed that the 149 top institutions were grouped into 8 clusters, each covering approximately a single country, suggesting that international cooperation among institutions should be strengthened. The core author extraction revealed changes in the most prolific authors. The keyword analysis revealed clustering and top citation bursts. The cocitation analysis of references from 2010 to 2020 revealed the number of citations and the centrality of the top articles.

Conclusions
This study revealed trends in research and public interest in immune checkpoint blockade for melanoma. Our findings suggest that the field is growing rapidly, has several core authors, and that the United States is taking the lead position. Moreover, cooperation between countries should be strengthened, and future research hot spots might focus on deeper exploration of drug mechanisms, prediction of treatment efficacy, prediction of adverse events, and new modes of administration, such as combination therapy, which may pave the way for further research.
Barriers to Clinical Trial Participation: Comparative Study Between Rural and Urban Participants
Authors: Mudaranthakam Dinesh Pal , Gajewski Byron , Krebill Hope , Coulter James , Springer Michelle , Calhoun Elizabeth , Hughes Dorothy , Mayo Matthew , Doolittle Gary 
Published: March 2022

Background
The National Clinical Trials Network program conducts phase 2 or phase 3 treatment trials across all National Cancer Institute’s designated cancer centers. Participant accrual across these clinical trials is a critical factor in deciding their success. Cancer centers that cater to rural populations, such as The University of Kansas Cancer Center, have an additional responsibility to ensure rural residents have access and are well represented across these studies.

Objective
There are scant data available regarding the factors that act as barriers to the accrual of rural residents in these clinical trials. This study aims to use electronic screening logs that were used to gather patient data at several participating sites in The Kansas University of Cancer Center’s Catchment area.

Methods
Screening log data were used to assess what clinical trial participation barriers are faced by these patients. Additionally, the differences in clinical trial participation barriers were compared between rural and urban participating sites.

Results
Analysis revealed that the hospital location rural urban category, defined as whether the hospital was in an urban or rural setting, had a medium effect on enrolment of patients in breast cancer and lung cancer trials (Cohen d=0.7). Additionally, the hospital location category had a medium effect on the proportion of recurrent lung cancer cases at the time of screening (d=0.6).

Conclusions
In consideration of the financially hostile nature of cancer treatment as well as geographical and transportation barriers, clinical trials extended to rural communities are uniquely positioned to alleviate the burden of nonmedical costs in trial participation. However, these options can be far less feasible for patients in rural settings. Since the number of patients with cancer who are eligible for a clinical trial is already limited by the stringent eligibility criteria required of such a complex disease, improving accessibility for rural patients should be a greater focus in health policy.
A Cancer Exercise Toolkit Developed Using Co-Design: Mixed Methods Study
Authors: Dennett Amy M , Tang Clarice Y , Chiu April , Osadnik Christian , Granger Catherine L , Taylor Nicholas F , Campbell Kristin L , Barton Christian 
Published: March 2022

Background
Access to exercise therapy for cancer survivors is poor. Professional development to support exercise professionals in delivering these interventions is needed. Few online resources exist for exercise professionals to address this issue.

Objective
To develop and evaluate a freely available online toolkit to support exercise professionals working with cancer survivors.

Methods
A 2-phase, experience-based co-design approach was used to develop and evaluate the online toolkit. The two phases were as follows: 1) needs identification and co-design of resources and platform and 2) pilot evaluation. Four co-design workshops were conducted, transcribed, and thematically analyzed to identify key elements for the toolkit. For the pilot evaluation, a customized survey (the Determinants of Implementation Behavior Questionnaire) was distributed to exercise professionals at baseline and 3 months after launch of the online toolkit to determine its usability, utility, and effectiveness in improving their knowledge, confidence, and behavior. Results were reported as the median and interquartile range and changes were calculated using non-parametric tests. Website analytics described site usage after the initial evaluation.

Results
Twenty-five exercise professionals participated in co-designing 8 key elements of the online Cancer Exercise Toolkit: the homepage and pages for getting started, screening and safety, assessment, exercise prescription, education, locations, and resources. For the pilot evaluation, 277/320 respondents (87% of whom were physiotherapists) from 26 countries completed the survey at baseline, with 58 exercise professionals completing follow-up surveys at 3 months. Exercise professionals’ knowledge, skills, and confidence in delivering exercise therapy to cancer survivors increased 3 months after baseline (items 1, 6, and 8: median score 5, IQR 3 to 6) to follow-up (items 1 and 6: median score 6, IQR 5 to 6; item 8: median score 5, IQR 5 to 7; P<.001) on a 1 to 7 Likert scale. Most participants (35/44, 80%) agreed or strongly agreed they would recommend the toolkit to colleagues. In the 6 months following the pilot evaluation, the toolkit received an average of 866 views per month.

Conclusions
The co-designed online Cancer Exercise Toolkit was a useful resource for exercise professionals that may increase their knowledge, skills, and confidence in providing exercise therapy to cancer survivors.