bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of post-traumatic stress disorders in women victims of intimate partner violence: a mixed methods comparison at initial care in coordinated and uncoordinated care facilities in France
Authors: Roland Noémie , Delmas Noëlla , El-Khoury Fabienne , Bardou Alice , Yacini Leila , Feldmann Laure , Hatem Ghada , Mahdjoub Sarah , Bardou Marc 
Published: November 2022

Abstract
Background: Intimate Partner Violence (IPV) has serious consequences on the mental health of victims-survivors such as Post-Traumatic Stress Disorder (PTSD). « La Maison des Femmes » (MdF, Women’s Home) is a French original medical and social structure specifically dedicated to provide multidisciplinary care for victims-survivors of IPV. The main objective of this study was to examine the prevalence of PTSD in victims-survivors of IPV consulting at the MdF or in two Municipal Health Centers (MHCs) located in the same area of the Paris conurbation.
Methods: We conducted an observational survey from July 2020 to June 2021 in the MdF and in two MHCs. All women aged 18 years and over having suffered from IPV were eligible. PTSD diagnosis was assessed using the PTSD self-report checklist of symptoms defined in the DSM-5 (PCL-5). We solicited data on the level of self-rated global health, the substances use, and the possibility of reaching women by phone in the 6 months following the inclusion visit. We also conducted qualitative interviews with a sub-sample of the women, asking for victims-survivors’ perceptions of the effect of the care provided at MdF and perceptions of their specific needs.
Results: A total of 67 women (mean age: 34 years old [Standard Deviation=9.7]) responded to our questionnaire (40 in the MdF, 12 in the MHC-1 and 15 in the MHC-2). PTSD diagnosis was retained for 40 women (59.7%) (PCL-5 score ≥33). The prevalence of PTSD was quite similar between the three groups. Around 30% of participants (n=23) self-rated their global health as bad or very bad, less than 30% (n=18) of women were regular smokers. Six months after inclusion, a half of participants (52.2%) had been reached by phone. Analysis of the nine qualitative interviews clarified victims-survivors’ perceptions of the MdF’s specific care: social networking, multidisciplinary approach, specialized listening, healthcare facilities, evasion and “feeling at home”.
Conclusions The prevalence of PTSD was high among the three centers. This mixed-methods comparison will serve as a pilot study for a larger comparative trial to assess the impact of the MdF on victims-survivors’ mental health outcomes comparatively with the impact of non-dedicated structures.
Development of an Automated Fibre Placement-based Hybrid Composite Wheel for a Solar Powered Car
Authors: Air Alexander , Shamsuddoha Md , Oromiehie Ebrahim , Prusty B. Gangadhara 
Published: November 2022

Abstract
Substantial range, handling and acceleration improvements in high-performance vehicles can be achieved by weight reduction. An important area for weight reduction on a car is the wheels. A prototype carbon fibre/epoxy wheel has been developed using a combination of automated fibre placement (AFP) and hand layup for the Sunswift 7 solar car. A three-piece wheel design that utilises each process where best suited has been analysed and optimised using the ANSYS ACP PrepPost suite, manufactured, and mechanically tested. The wheel disc was produced using AFP and featured selective reinforcement in the form of spokes. The laminate for the disc has been optimised using CGTech VERICUT VCP and VCS to minimise gaps and overlaps and simulate the manufacturing process. The rim and tyre mounting region of the wheel have been manufactured using hand layup, and adhesively bonded to the disc. This hybrid manufacturing approach has demonstrated an advancement in the feasibility of combining traditional and automated composites manufacturing, providing insight into the manufacture of parts and products with complex shapes in the future.
Facile route for synthesis of Er doped Cobalt Nanoferrites and Investigation on Structural, Magnetic and Humidity sensor properties
Authors: Reddy R. Anitha , Rao A. Venkateswara , Babu B. Rajesh , Srid B , Sreela K 
Published: November 2022

Abstract
In this work, Er3+ doped Cobalt Nanoferrite particles CoErxFe2−xO4 (x = 0.0, 0.01, 0.03, 0.05) were synthesized using optimized citrate-gel auto-combustion method and analyzed for Humidity sensor applications. Preliminary X-ray diffraction and Raman spectroscopic studies and confirm the formation of single-phase spinel structure. Average crystallite sizes from Williamson-Hall method are in the range 28 nm to 32 nm, which are in close agreement with TEM data. Temperature dependent magnetization ZFC-FC curves shows above room temperature blocking temperature. Hysteresis loops obtained by vibrating sample magnetometry clearly enhances the magnetization of cobalt ferrite. Electrical resistance measurements in different relative humidity conditions (RH 10–95%) and frequencies were done using a High Frequency LCR Meter. Er doped Cobalt ferrite samples shows a decrease in electrical resistance and improved sensitivity compared to the pure ones. The variation of Resistance with respect to humidity conditions suggested that Er doped Cobalt ferrite nanoparticles are potentially suitable for resistive humidity sensor applications.
Canine distemper virus N protein induces autophagy to facilitate viral replication
Authors: Chen Fei , Guo Zijing , Zhang Rui , Zhang Zhixiong , Hu Bo , Bai Ling , Zhao Shuaiyang , Wu Yongshu , Zhang Zhidong , Li Yanmin 
Published: November 2022

Abstract
Background
Canine distemper virus (CDV) is one of the most contagious and lethal viruses known to the Canidae, with a very broad and expanding host range. Autophagy serves as a fundamental stabilizing response against pathogens, but some viruses have been able to evade or exploit it for their replication. However, the effect of autophagy mechanisms on CDV infection is still unclear.
Results
In the present study, autophagy was induced in CDV-infected Vero cells as demonstrated by elevated LC3-II levels and aggregation of green fluorescent protein (GFP)-LC3 spots. Furthermore, CDV promoted the complete autophagic process, which could be determined by the degradation of p62, co-localization of LC3 with lysosomes, GFP degradation, and accumulation of LC3-II and p62 due to the lysosomal protease inhibitor E64d. In addition, the use of Rapamycin to promote autophagy promoted CDV replication, and the inhibition of autophagy by Wortmannin, Chloroquine and siRNA-ATG5 inhibited CDV replication, revealing that CDV-induced autophagy facilitated virus replication. We also found that UV-inactivated CDV still induced autophagy, and that nucleocapsid (N) protein was able to induce complete autophagy in an mTOR-dependent manner.
Conclusions
this study for the first time revealed that CDV N protein induced complete autophagy to facilitate viral replication.
DUSP1 mediates BCG induced apoptosis and inflammatory response in THP-1 cells via MAPKs/NF-κB signaling pathway
Authors: Liu Zhanyou , Wang Jianhong , Dai Fan , Zhang Dongtao , Li Wu 
Published: November 2022

Abstract
Tuberculosis (TB) is a zoonotic infectious disease caused by Mycobacterium tuberculosis (Mtb). Apoptosis and necrosis caused by the interaction between the host and the pathogen, as well as the host’s inflammatory response, play an important role in the pathogenesis of TB. Dual-specificity phosphatase 1 (DUSP1) plays a vital role in regulating the host immune responses. However, the role of DUSP1 in the regulation of THP-1 macrophage apoptosis induced by attenuated Mycobacterium bovis Bacillus Calmette-Guérin (BCG) infection remains unclear. In the present study, we report that infection with BCG significantly induces macrophage apoptosis and induces the production of DUSP1, TNF-α and IL-1β. DUSP1 knockdown significantly inhibited BCG-induced macrophage apoptosis and activation of MAPKs/NF-κB signaling pathway. In addition, DUSP1 knockdown suppressed BCG-induced inflammation in vivo. Taken together, this study demonstrates that DUSP1, as a regulator of MAPKs/NF-κB signaling pathway, plays a novel role in BCG-induced macrophage apoptosis and inflammatory response.
An investigation of water quality of commercially available bottled drinking water in Dhaka city
Authors: Ankon A. A. , Chowdhury R. M. , Ahmed S. , Shoaib S. R. , Akter S. 
Published: November 2022

Abstract
The past few years have seen an increasing demand for drinking water in modern society with a focus on safety, taste and Dietary Reference Intakes (DRI). Mineral water is now marketed as a popular commercial product due to health concerns. The question of the quality of tap water helped to raise the popularity of commercial drinking water. Besides that, commercial water brands promoted their water as “Mineral water” which encourages modern people to consume bottled water to maintain their daily dietary requirements. The research investigated the status of the physicochemical quality of bottled water in Dhaka city. A total of eleven locally available and popular mineral drinking water brands were investigated. The study also analyzed the “Taste Index” and “Health Index” which were calculated by the measured parametric values. These indexes were leveraged to create a classification database of the commercially marketed bottled drinking water brands. The study showed that the majority of the physicochemical parameters of the water quality of the samples meet the Bangladesh standard. However, the mineral content (e.g., Calcium and Magnesium) of all the sample waters was found to be very low and below Bangladesh standard—posing the risk of mineral deficiency from long-term consumption. The outcome of the study unraveled the real status of bottled water drinking water quality and would guide the stakeholders to avoid any potential health risks.
Moderately hypofractionated post-operative radiation therapy for breast cancer: Preferences amongst radiation oncologists from countries in Latin America and the Caribbean
Authors: Marta Gustavo Nader , Franco Rejane Carolina de Oliveira , Carvalho Heloísa de Andrade , Gouveia André Guimaraes , Gössling Gustavo Cartaxo de Lima , de Jesus Rafaela Gomes , de Moraes Fabio Ynoe , Ferraris Gustavo , Schuffenegger Pablo Munoz , Bardales Gustavo Sarria , Chacón María Adela Poitevin , Murillo Raúl , Sánchez Luis Ernesto Moreno , Gamarra-Cabezas Elizabeth , Rosa Arthur Accioly , Silva Maurício Fraga da , de Mattos Marcos Duarte , Morais Diego Chaves Rezende , de Castro Douglas Guedes , Pra Alan Dal , Amêndola Beatriz , Barros José Máximo , Lara Tomas Merino , Isa Nicolás , Moya Dolores de la Mata , Hidalgo Iván , Velilla Diego Gimenez , Loayza Lijia Elizabeth Avilés , Montenegro Francisco Gomez , Chacin Nestor O. Sanchez , Werutsky Gustavo , Viani Gustavo Arruda 
Published: November 2022

Abstract
Purpose
The safety and effectiveness of moderately hypofractionated post-operative radiation therapy for breast cancer were demonstrated by several trials. This study aimed to evaluate the current patterns of practice and to assess possible aspects that affect the decision-making process regarding the use of fractionation in breast cancer patients in Latin America and the Caribbean (LAC).
Methods
Radiation oncologists from LAC were invited to contribute to this this study. A 38-question survey was used to evaluate their opinions.
Results
A total of 173 radiation oncologists from 13 countries answered the questionnaire. The majority of respondents (84.9%) preferred moderately hypofractionated post-operative radiation therapy as their first choice in cases of whole breast irradiation. For whole breast plus regional nodal irradiation, post-mastectomy (chest wall and regional nodal irradiation) without reconstruction, and post-mastectomy (chest wall and regional node irradiation) with reconstruction hypofractionated post-operative radiation therapy was preferred by 72.2% 71.1%, and 53.7% of respondents, respectively. Breast cancer stage, and flap-based breast reconstruction were the factors associated with absolute contraindications for the use of hypofractionated schedules.
Conclusion
Even though moderately hypofractionated post-operative radiation therapy for breast cancer is considered a new standard to the vast majority of the patients, its unrestricted application in clinical practice across LAC still faces reluctance.
Assessing contraceptive use as a continuum: outcomes of a qualitative assessment of the contraceptive journey
Authors: Simmons Rebecca G. , Baayd Jami , Waters Megan , Diener Zoë , Turok David , Sanders Jessica N. 
Published: November 2022

Abstract
Background:Contraceptive use is often a multi-decade experience for people who can become pregnant, yet few studies have assessed how this ongoing process impacts contraceptive decision-making in the context of the reproductive life course.
Methods:We conducted in-depth interviews assessing the contraceptive journeys of 33 reproductive-aged people who had previously received no-cost contraception through a contraceptive initiative in Utah. We coded these interviews using modified grounded theory.
Results:A person’s contraceptive journey occurred in four phases: identification of need, method initiation, method use, and method discontinuation. Within these phases, there were five main areas of decisional influence: physiological factors, values, experiences, circumstances, and relationships. Participant stories demonstrated the ongoing and complex process of navigating contraception across these ever-changing aspects. Individuals stressed the lack of any “right” method of contraception in decision-making and advised healthcare providers to approach contraceptive conversations and provision from positions of method neutrality and whole-person perspectives.
Conclusions:Contraception is a unique health intervention that requires ongoing decision-making without a particular “right” answer. As such, change over time is normal, more method options are needed, and contraceptive counseling should account for a person’s contraceptive journey.
Alternative Control With Oils and Plant Extracts of the Pulgon Lipaphis erysimi (Kaltenbach, 1843) on Couve Brassica oleracea L. var. acephala, in the Municipality of Cruzeiro Do Sul, Acre
Authors: Almeida Jalluza , Godoy Karlla 
Published: November 2022

Abstract

With the crisis and the increase in agricultural pests, there was a need for evolution in the correct management of insects in major crops. Biological control provides for the use of natural inputs as toxicological agents against existing enemies in organic farming. In this way, the use of botanical insecticides regulates the natural balance of species. To obtain new methods of control and management, essential oils were used to eliminate aphids present in cabbage specimens, thus allowing the continuity of vegetable production away from pests. In this study, we will be able to evaluate the viability of different vegetable oils as natural insecticides on aphids of cabbage. It was concluded that the mortality rate showed 100% efficiency on aphids at concentrations of 10%, 25%, 50% and 100% in the different oils tested. According to what was observed, the mortality time showed that Mauritia flexuosa obtained the shortest time as being the best to kill the aphids, followed by the other oils. It is worth noting that for use on leaf specimens, only the concentrations 10% and 25%, regardless of the oils, offered no commercial damage.
A Prediction Model for Childhood Obesity Risk Using the Machine Learning Method: A Panel Study on Korean Children
Authors: Lim Heemoon , Lee Hyejung , Kim Jeongyeon 
Published: November 2022

Abstract
Young children are increasingly exposed to an obesogenic environment through increased intake of processed food and decreased physical activity. Mothers’ perceptions of obesity and parenting styles also influence children’s abilities to maintain a healthy weight. This study aimed to develop a prediction model for childhood obesity in 10-year-olds and to identify relevant risk factors using a machine learning method. Data on 1185 children and their mothers were obtained from the Korean national panel study. A prediction model for obesity was developed based on factors of both children (gender, eating habits, activity, and previous body mass index) and their mothers (education level, self-esteem, and body mass index). These factors were selected based on the least absolute shrinkage and selection operator. The prediction model was validated with the Area Under the Receiver Operator Characteristic Curve of 0.82 and an accuracy of 76%. Besides body mass index for both children and mothers, significant risk factors for childhood obesity were less physical activity among children and higher self-esteem among mothers. This study adds new evidence demonstrating maternal self-esteem is related to children’s body mass index. Future studies are needed to develop effective strategies for screening young children at risk for obesity, along with their mothers.
A single dose intranasal combination panebolavirus vaccine
Authors: Bukreyev Alexander , Malherbe Delphine , Kimble J. Brian , Atyeo Caroline , Fischinger Stephanie , Hyde Matthew , Alter Galit 
Published: November 2022

Abstract
Ebolaviruses Ebola (EBOV), Sudan (SUDV) and Bundibugyo (BDBV) cause severe human disease, which may be accompanied by hemorrhagic syndrome, with high case fatality rates. Monovalent vaccines do not offer cross-protection against these viruses whose endemic areas overlap. Therefore, development of a panebolavirus vaccine is a priority. As a vaccine vector, human parainfluenza virus type 3 (HPIV3) has the advantages of needle-free administration and induction of both systemic and local mucosal antibody responses in the respiratory tract. We developed a HPIV3-vectored combination vaccine against EBOV, SUDV and BDBV. To minimize the anti-vector immunity, HPIV3 envelope genes were removed from the vaccine constructs which express only the ebolavirus envelope protein – glycoprotein (GP). A single intranasal vaccination of guinea pigs or ferrets with the trivalent combination vaccine elicited humoral responses to each of the targeted ebolaviruses, including binding and neutralizing antibodies, as well as Fc-mediated effector functions. This vaccine protected animals from death and disease caused by lethal challenges with EBOV, SUDV or BDBV. Notably, the combination vaccine elicited protection which was comparable to that induced by the monovalent vaccines, thus demonstrating the value of this combination trivalent vaccine.
Superconductivity in a ferroelectric-like topological semimetal SrAuBi
Authors: Takahashi Hidefumi , Sasaki Tomohiro , Nakano Akitoshi , Takahashi Masayuki , Mayo Alex , Onose Masaho , Ishiwata Shintaro 
Published: November 2022

Abstract
Given the rarity of metallic systems that exhibit ferroelectric-like transitions, it is apparently challenging to find a system that simultaneously possesses superconductivity and ferroelectric-like structural instability. Here, we report the observation of superconductivity at 2.4 K in a layered semimetal SrAuBi characterized by strong spin-orbit coupling (SOC) and ferroelectric-like lattice distortion. Single crystals of SrAuBi have been successfully synthesized and found to show a polar-nonpolar structure transition at 214 K, which can be associated with the buckling of Au-Bi honeycomb lattice. On the basis of the band calculations considering SOC, we found significant Rashba-type spin splitting and symmetry-protected multiple Dirac points near the Fermi level. We believe that this discovery opens up new possibilities of pursuing exotic superconducting states and relevant novel responses inherent to the strong SOC and topological band structure.
Demographic structure across all known populations of the rheophyte Dyckia brevifolia Baker (Bromeliaceae) in the Itajaí-Açú River, Southern Brazil
Authors: Rogalski Juliana Marcia , Reis Maurício Sedrez , Reis Ademir 
Published: November 2022

Abstract
Understanding the distribution and demographic structure of populations is essential for species conservation. In Brazil, the rheophyte group has been greatly affected by the construction of hydroelectric dams. All know populations of Dyckia brevifolia along Itajaí-Açu River were studied. The plants were classified as seedlings, immature or repoductive rosettes. In addition, the number of dead rosettes, except for seedlings, was determined in five populations of D. brevifolia. The total number of rosettes per population ranged from 273 to 7,185, totaling 30,443 rosettes, and 1,789 seedlings (5.9%). Only 2.4% of rosettes occurred isolated and 97.6% occurred clumped into 2,254 clumps. The number of rosettes per clump ranged from two to 339 rosettes. The percentage of reproductive rosettes per population ranged from 7.8 to 26.7%. The correlation between the number of clumps or between the total number of rosettes and the area of occupation was significant and positive (r = 0.82; P < 0.05). The production of offshoots (1-4) occurred on immature and reproductive rosettes. D. brevifolia has herbivory by Hydrochaeris hydrochaeris. These rosettes die or often resprout, emitting from 1 to 20 offshoots. The populations did not present a pattern of distribution of rosettes in the diametric classes, but in all populations a decrease in the number of rosettes can be observed in the classes with the largest diameter. The small area of occupation (9,185 m2) showed environmental specificit and vulnerable to habitat loss and environmental changes. Therefore, the maintenance these sites is essential for the long-term conservation of D. brevifolia.
Influence of effective omalizumab treatment on eosinophils in allergic asthma with comorbidities
Authors: Yan Huacheng , Sun Lin , Ni Yingmeng , Du Juan , Liu Dong , Wang Ping , Cao Jin , Xu Guofang , Tao Yi , Dai Ranran , Tang Wei 
Published: November 2022

Abstract
Background
Omalizumab is an effective anti-immunoglobulin E(IgE) treatment for allergic asthma. Eosinophil plays a critical role in the pathogenesis of allergic airway inflammation. This study aimed to evaluate the efficacy of omalizumab on comorbidities of allergic asthma and explore influence of omalizumab on circulating eosinophils.
Methods
Allergic asthmatics enrolled in the study were treated with omalizumab for at least 16 weeks and exhibited a good or excellent response according to the global evaluation of treatment effectiveness (GETE) assessed by each patient and specialist physician. Asthma Control Test (ACT) and Mini Asthma Quality of Life Questionnaire (Mini-AQLQ) for asthma, Mini Rhino-conjunctivitis Quality of Life Questionnaire (Mini-RQLQ) for allergic rhinitis (AR), Visual Analogue Scale (VAS) for systemic allergic symptoms, Leicester Cough Questionnaire (LCQ) for cough variant asthma (CVA) and Self-rating Anxiety Scale (SAS) were collected at baseline and week 16. For eosinophil functional evaluation, peripheral eosinophils were separated and examined the expression of human leukocyte antigen DR (HLA-DR) and co-stimulatory molecules CD80, CD86 and CD40 by Flow Cytometry and serum to measure the concentration of eotaxin-1 before and after 16 weeks of omalizumab treatment.
Results
Totally 32 allergic asthma patients who responded positively to omalizumab treatment were included. Omalizumab increased LCQ (3.03, p = 0.009), reduced mini-RQLQ (-8.5, p = 0.047), and SAS (-5.08, p = 0.04) in CVA patients, or allergic asthmatics complicating AR or anxiety, respectively. Omalizumab responders showed a significant decline in expression of co-stimulatory molecules CD40, CD80, and CD86 on peripheral eosinophils and in serum eotaxin-1 concentration after treatment. Negative correlations (r=-0.61, p = 0.048) were observed between the change in CD80+ eosinophils and the change in FEV1/FVC% predicted and MEF25% after omalizumab treatment.
Conclusion
Our findings show a unique role of omalizumab in reducing co-stimulator molecules expression on eosinophil and serum eotaxin-1 levels in allergic asthmatics with comorbidities.