bluuebunny/crossref_metadata_2025_split huggingface dataset:
HEART RATE VARIABILITY IS AFFECTED IN YOUNG ADULT CELIAC PATIENTS, INDICATING AUTONOMIC DYSFUNCTION AND INCREASED CARDIOVASCULAR RISK
Authors: UZEL Eliz , UZUNGET Sezen 
Published: December 2022

Aim: Celiac Disease (CD) is a common autoimmune disease that can present at any age with varied symptoms. Cardiac involvement including vascular and arrhythmic disturbances has an important prognostic value in patients with autoimmune disorders. The aim of this study was to evaluate the effects of CD on cardiovascular autonomic functions by measuring the indices of heart rate variability (HRV).
Materials and Methods: Ninety-one CD patients and the ninety-three healthy volunteers were included in the study. We examined both time domain and frequency domain indices of HRV measured by 24-hour ambulatory electrocardiography.
Results: All of the time domain and frequency domain HRV parameters, with the exceptions of low frequency power and low frequency to high frequency ratio, were significantly lower in patients with CD compared to the control (p < 0.01). This difference retained for most of the HRV parameters when daytime and nighttime HRV parameters were compared separately. Correlation analysis revealed significant associations of HRV parameters with hemoglobin and ferritin levels and with duration of CD (p < 0.01). No correlation was found between HRV parameters and anti-tissue transglutaminase IgA and IgG levels which indicate the activity of the disease.
Conclusion: The study confirmed that patients with CD have reduced HRV, indicating the presence of objective autonomic dysfunction and increased cardiovascular risk.
Identifikasi Lapisan Tanah dan Batuan Dengan Metode Geolistrik Konfigurasi Schlumberger Pada Daerah Durjo, Kabupaten Jember, Jawa Timur
Authors: Faizin Nur , Irawan Januar Fery , Aminah Siti 
Published: December 2022

Resistivitas material dapat diukur dengan dimensi dan hambatan listrik material tersebut. Salah satu model resistivitas semu adalah satu Dimensi (1-D). Resistivitas semu dapat diperoleh dengan metode geolistrik. Salah satu konfigurasi untuk metode geolistrik adalah Konfigurasi Schlumberger. Konfigurasi ini umumnya digunakan dalam survey geolistrik. Keunggulan konfigurasi ini adalah kemampuan deteksi ketidakhomogenan lapisan batuan permukaan dan penetrasi arus dapat mencapai 20%. Konfigurasi Schlumberger dilakukan dalam bentuk lintasan atau line. Data yang diperoleh pada penelitian ini adalah beda potensial (ΔV), resistansi (R), dan jarak elektroda (x). Jumlah lintasan yang digunakan dalam penelitian ini adalah dua. Setiap lintasan diset sepanjang 100 m mendatar dengan jarak spasi injeksi arus 5 m. sedangkan jarak antar lintasan adalah 30 m. Setelah dibandingkan nilai resistivitas semu antara hasil analisa data dengan referensi, diketahui bahwa lintasan 1 terdapat batuan sedimen dimana batuan sedimen ini memiliki nilai resistivitas semu berorde 10-103 Ωm. Batuan ini ditemukan pada kedalaman 6,1-38,47 m. Jenis batuan sedimen yang mungkin adalah batu kapur, batu serpih atau batu pasir. Hasil yang diperoleh pada lintasan 2 hampir sama dengan lintasan 1. Sehingga lintasan 2 kemungkinan jenis batuan yang muncul adalah batuan sedimen. Batuan ini berada pada kedalaman 2,98-61,73 m. Batuan ini merupakan batuan yang menopang salah satu kebun kopi yang berada pada perkebunan kopi durjo.
PENINGKATAN PEMBELAJARAN MENULIS RESENSI DENGAN METODE DUTA DJARUM QRR PADA SISWA KELAS XI IPS 1 DI SMAN 1 KARAS TAHUN PELAJARAN 2019/2020
Authors: Peni Rustami Yuaftika 
Published: December 2022

Faktor penyebab rendahnya kemampuan menulis siswa meliputi faktor internal dan eksternal. Faktor penyebab internal adalah siswa cenderung kurang dapat berimajinasi, mengungkapkan ide, dan kemudian menuangkan kata ke dalam bentuk tulisan, siswa belum mampu merangkai kata-kata menjadi kalimat dan menyusunnya ke dalam tulisan yang utuh, serta siswa juga kurang memperhatikan ejaan dan tanda baca dalam menulis. Tujuan dari penelitian ini adalah (1) memaparkan penerapan metode Duta Djarum QRR dalam menulis resensi pada siswa kelas XI IPS 1 di SMAN 1 Karas tahun pelajaran 2019/2020. (2) Mendeskripsikan hasil belajar menulis resensi pada siswa kelas XI IPS 1 di SMAN 1 Karas tahun pelajaran 2019/2020 dengan menggunakan metode Duta Djarum QRR. Metode Duta Djarum QRR merupakan singkatan dari dua tamu dua jaga rumah question read recite. Metode pembelajaran ini merupakan metode pembelajaran modifikasi dari metode TS-TS (two stay-two stray) dengan metode membaca SQ3R (survey, question, read, recite, review). Yang membedakan metode TS-TS dengan Duta Djarum ini adalah adanya setingan membaca QRR (Question Read Recite) pada saat pembelajaran. Di mana QRR sendiri merupakan bagian dari metode membaca SQ3R. Hasil belajar Bahasa Indonesia siswa mengalami peningkatan setelah menggunakan metode pembelajaran Duta Djarum QRR. Hal itu dapat ditunjukkan dari nilai rata-rata hasil LKS yang mengalami peningkatan yaitu dari nilai 76,57 pada siklus I menjadi 85,44 pada siklus II. Metode pembelajaran Duta Djarum QRR juga dapat meningkatkan keaktifan siswa pada pembelajaran Bahasa Indonesia dengan materi menulis resensi.
Kata Kunci: Menulis Resensi, Duta Djarum QRR
Physiological Response of Cantang Grouper as Zeylanicobdella Control with Papaya Leaf Extract as an Antiparasitic Agent
Authors: Amali Ikmalia , Mahasri Gunanti 
Published: December 2022

Permintaan pasar terhadap ikan kerapu cantang yang terus meningkat menyebabkan intensifikasi budidaya tidak dapat dihindarkan. Salah satu kendala utama dalam upaya peningkatan produksi ikan kerapu adalah serangan penyakit. Alternatif bahan obat yang dapat digunakan dalam pengendalian penyakit yaitu dengan menggunakan daun pepaya lokal dan daun pepaya jepang. Tujuan dari penelitian ini adalah untuk menganalisis pengaruh konsentrasi dan lama waktu perendaman ekstrak daun pepaya sebagai antiparasit terhadap kadar glukosa darah dan tingkat konsumsi oksigen selama proses pengendalian Zeylanicobdella pada ikan kerapu cantang. Metode yang digunakan adalah metode eksperimental dengan rancangan acak lengkap faktorial 6 perlakuan dan 3 ulangan. Hasil dari penelitian ini yaitu diperoleh hasil rata-rata kadar glukosa yang diberi perlakuan ekstrak daun pepaya jenis berbeda selama dua jam menunjukkan bahwa pada faktor A dan B terdapat pengaruh dan interaksi yang sangat nyata (p<0,01) terhadap kadar glukosa darah, serta interaksi yang nyata (p<0,05) antara faktor A dan B terhadap tingkat konsumsi oksigen. Berdasarkan hasil penelitian dapat disimpulkan bahwa terdapat interaksi yang sangat nyata antara lama waktu perendaman dan konsentrasi ekstrak daun pepaya lokal dan pepaya jepang sebagai bahan antiparasit terhadap peningkatan kadar glukosa darah dan terdapat interaksi yang nyata terhadap tingkat konsumsi oksigen selama proses pengendalian Zeylanicobdella pada ikan kerapu cantang

Kata Kunci: Daun pepaya jepang, Daun pepaya lokal, Kerapu cantang,Zeylanicobdella

Abstract
Efforts to increase grouper production are disease attacks. Alternative medicinal ingredients that can be used in disease control are using local papaya leaf and Japanese papaya leaf. The purpose of this study was to analyze the effect of concentration and duration of dipping in papaya leaf extract as an antiparasitic on blood glucose levels and oxygen consumption levels during the Zeylanicobdella control process in cantang grouper. The method used is an experimental method with a completely randomized factorial design with 6 treatments and 3 replications. The results of this study are the average results of glucose levels treated with different types of papaya leaf extract for two hours indicate that factors A and B have a very significant effect and interaction (p<0.01) on blood glucose levels, and significant interaction (p<0.05) between factors A and B on the level of oxygen consumption. Based on the results of the study, it can be concluded that there is a very significant interaction between the length of soaking time and the concentration of local papaya leaf extract and Japanese papaya as antiparasitic ingredients to increase blood glucose levels and there is a significant interaction with the level of oxygen consumption during the Zeylanicobdella control process in cantang grouper.

Keywords:Japanese papaya leaf, Local papaya leaf, Cantang grouper, Zeylanicobdella
Faktor yang mempengaruhi Kepuasan Kerja Perawat selama pandemi Covid-19 di Beberapa Rumah sakit di Kalimatan Selatan
Authors: Rizany Ichsan , Yakin Rahimul , Rusydianur Rusydianur , Risnadi Didi , Adawiyah Robiatul , Fikri M. Khairul , Azhar Ahmad 
Published: December 2022

Pendahuluan: Tingkat kepuasan kerja perawat masih rendah di masa pandemi covid-19. Rendahnya kepuasan kerja disebabkan oleh beberapa faktor. Tujuan penelitian ini adalah untuk menganalisis faktor-faktor karakteristik perawat terhadap kepuasan kerja perawat selama masa covid-19 di beberapa rumah sakit di Kalimatan Selatan.
Metode: Penelitian ini menggunakan rancangan deskriptif analitik dengan desain cross-sectional. Penelitian dilakukan di tiga rumah sakit di Kalimantan Selatan. Jumlah responden adalah 164 perawat dengan menggunakan teknik cluster random sampling. Instrumen kepuasan kerja menggunakan MSQ. Data dianalisis dengan uji korelasi spearman dan uji kruskal-wallis.
Hasil: Penelitian ini didapatkan rerata usia perawat adalah 32,10 tahun, rerata masa kerja sebesar 7,11 tahun dengan rerata gaji sebesar Rp. 2.642.726,- . Perawat yang bekerja didominasi oleh perawat kontrak / BLUD sebesar 62,4% (103 orang). Jenjang karir perawat didominasi oleh PK I sebanyak 38,8% (64 orang). Ada hubungan yang bermakna antara usia (p= 0,0001; r= -0,318), lama kerja (p= 0,0001; r= -0,319), status kepegawaian (p= 0,020), jenjang karir (p= 0,013) dengan kepuasan kerja perawat.
Kesimpulan: Faktor yang mempengaruhi kepuasan kerja perawat adalah usia, lama kerja, status kepegawaian, dan jenjang karir. Diharapkan manajer memberikan motivasi kepada perawat agar kepuasan tetap tinggi dan mencintai pekerjaan dengan sepenuh jiwa sesuai jenjang karir.
Experience of Nurses in Implementing Patient Safety Culture at USU Hospital
Authors: Zuraidah Zuraidah , Nurmaini  , Simamora Roymond H. 
Published: December 2022

A holistic patient safety program requires a crucial and fundamental component: patient safety culture. It is also critical in the evaluation of hospital safety and service quality. The purpose of the study was to find out how nurses at USU Hospital implemented a patient safety culture. The Collaizzi approach to descriptive phenomenology was applied in the study design. Purposive sampling was used to choose fifteen participants who met the inclusion criteria. In-depth interviews were used to acquire the information. Verbatim description was used in the analysis and interpretation. Five themes emerged from the study, namely: (1) accomplishment of patient safety goals with the support from the hospital management, (2) information provision about patient nursing care to improve patient safety, (3) report of patient safety incidents, (4) obstacles encountered by nurses in implementing patient safety culture, and (5) expectation that nurse implement safety culture. It suggested that nursing services facilitate nurses with training on patient safety culture regularly to improve their behaviors in reporting any patient safety incidents.
Forecasting Jumlah Penggunaan Obat Digestive Enzymes dengan Algoritma GRU
Authors: Zaky Abi Mahan 
Published: December 2022

<span lang="EN-US">Obat-obatan banyak digunakan untuk mencegah atau menyembuhkan penyakit. Salah satu obat yang sering digunakan untuk meredakan sakit perut adalah</span><span lang="EN-US">obat yang mengandung <em>Digestive Enzymes</em>. Rumah sakit dan institusi</span><span lang="EN-US">kesehatan lainnya sangat membutuhkan obat jenis ini. Rumah Sakit dan</span><span lang="EN-US">institusi kesehatan lain harus memastikan ketersediaan obat untuk pasien. Situasi ini memaksa institusi kesehatan untuk menghadapi</span><span lang="EN-US">ketidakpastian penggunaan obat. Rumah sakit sebagai salah satu institusi kesehatan memiliki beberapa tantangan. Salah satu tantangan yang harus</span><span lang="EN-US">dihadapi adalah untuk menjamin ketersediaan obat bagi pasien. Kemampuan </span><em><span>forecasting</span></em><span lang="EN-US"> dapat membantu memastikan ketersediaan obat di rumah sakit. Di</span><span lang="EN-US">penelitian ini akan menyajikan model </span><em><span>forecasting</span></em><span lang="EN-US"> dengan menggunakan metode </span><em><span>Gated Recurrent Unit</span></em><span lang="EN-US"> (</span><span>GRU</span><span lang="EN-US">) untuk memprediksi kebutuhan obat-obatan yang</span><span lang="EN-US">mengandung <em>Digestive Enzymes</em> di rumah sakit. Metode ini dipilih karena diketahui memiliki akurasi yang tinggi untuk memprediksi data stasioner.</span><span lang="EN-US">Salah satu metode yang digunakan dalam identifikasi input untuk metode </span><span>GRU</span><span lang="EN-US"> adalah dengan menggunakan <em>Autocorrelation Function</em> (ACF) dan <em>Partial</em></span><em><span lang="EN-US">Fungsi Autokorelasi</span></em><span lang="EN-US"> (PACF). Hasil penelitian ini menunjukkan bahwa penggunaan metode </span><span>GRU</span><span lang="EN-US"> cocok untuk </span><em><span>forecasting</span></em><span> data <em>timeseries </em></span><span lang="EN-US">dalam kumpulan data historis, dengan nilai </span><em><span>Root </span><span lang="EN-US">Mean Square</span></em><span lang="EN-US"> Error (</span><span>R</span><span lang="EN-US">MSE) </span><span>13,020446</span>
Modeling of High-Pressure and High-Temperature Microemulsion Experiments using HLD-NAC-Based Equation of State
Authors: Magzymov Daulet , Johns Russell T. , Hashim Hafsa , Dindoruk Birol 
Published: December 2022

Summary
Surfactant flooding is a promising technique that can reduce interfacial tension (IFT) between oil and water to ultralow values, mobilizing previously trapped oil. For reservoirs at moderate to high pressures, understanding and modeling how pressure affects the phase behavior of a surfactant-brine-oil system is important to the design and implementation of an efficient/cost-effective surfactant flooding project. Typically, however, phase behavior experiments and models of that phase behavior are made only at low pressures. The main objective of this paper is to show how to model experimental data in a unified way for a large range of pressure, temperature, and other parameters, using hydrophilic-lipophilic deviation (HLD) and net-average curvature (NAC)-based equation-of-state (EOS).
Pressure and temperature scans show that pressure has a significant effect on the surfactant microemulsion phase behavior, shifting it from an optimal three-phase system at low pressure to a nonoptimal two-phase system at high pressure. Further, multiple scans at different water/oil ratios (WORs) show a shift in the optimum indicating that phase behavior partitioning of the various components is changing with oil saturation. We obtained good fits of all experimental data including all two- and three-phase regions using a single tuned HLD-NAC EOS for a wide range of simultaneous variations in pressure, temperature, salinity, and overall composition. Such a simultaneous match and prediction by a single set of model parameters has never been done before. We also demonstrate the type of data needed for an accurate EOS. When input into a numerical simulator, the tuned EOS improves the predictions of the resulting phase behavior (size and shape of the two-phase lobes and three-phase regions) and IFTs with changing pressure, temperature, salinity, WORs, and surfactant/alcohol concentrations.
Formation of EpiTS embryoids
Authors: Girgin Mehmet Ugur , Lutolf Matthias 
Published: December 2022

Abstract
The difficulty of studying post-implantation development in mammals has sparked a flurry of activity to develop in vitro models, termed embryoids, based on self-organizing pluripotent stem cells. Previous approaches to derive embryoids either lack the physiological morphology and signaling interactions, or are unconducive to model post-gastrulation development. Here, we report a bioengineering-inspired approach aimed at addressing this gap. We employ a high-throughput cell aggregation approach to simultaneously coax mouse embryonic stem cells into hundreds of uniform epiblast-like aggregates in a solid matrix-free manner. When co-cultured with mouse trophoblast stem cell aggregates, the resulting hybrid structures initiate gastrulation-like events and undergo axial morphogenesis to yield structures, termed EpiTS embryoids, with a pronounced anterior development, including brain-like regions. We identify the presence of an epithelium in EPI aggregates as the major determinant for the axial morphogenesis and anterior development seen in EpiTS embryoids. Our results demonstrate the potential of EpiTS embryoids to study peri-gastrulation development in vitro.
Knowledge, Attitude, and Practice Toward Cervical Cancer Screening Among Female University Students in Ishaka Western Uganda
Authors: Usman Ibe Michael , Chama Sunday Naguledaticha , Aigbogun Eric Osamudiamwen , Kabanyoro Annet , Kasozi Keneth Iceland , Usman Comfort Ojochenemi , Diaz Mario Edgar Fernandez , Ndyamuhakyi Elisa , Onongha Comfort , Ochieng Juma John , Kanee Rogers Bariture , Ssebuufu Robinson 
Published: December 2022

Abstract
The objective of the study was to assess; the level of knowledge, attitude and practice on cervical cancer screening (CCS) among female university students (FUS) in Ishaka, western Uganda. The study was a descriptive cross-sectional study among FUS (n = 407) in western Uganda conducted after the first nationwide lockdown in Uganda. Information was collected using a questionnaire and descriptively presented as frequency and percentages. Majority of our respondents were medical students 283 (69.5%), below 25years 339 (83.3%), with Anglican Christian religious background 150 (36.9%). More respondents above the age of 25years (p = 0.0052) and those in the medical profession (p < 0.001) had more knowledge. More medical students had a better attitude (p = 0.0043) and favorable practices (0.0134) compared to their non-medical counterparts. There is a weak correlation between attitude (r = 0.206, p < 0.001) and practice (r = 0.181, p = 0.0003) with knowledge on CCS. Observation from the present study suggests the need for more efforts in the fight against cervical cancer and encouragement of positive attitude and practice towards cervical cancer screening and uptake of vaccination.
Laparoscopic adenomyomectomy combined with levonorgestrel-releasing intrauterine system is effective for long management of adenomyosis
Authors: Jiang Jilan , Yu Jin , Zhang Ye , Yang Yeping , Xu Hong , Sun Feng 
Published: December 2022

Abstract
Background: Laparoscopic adenomyomectomy combined with intraoperative placement of levonorgestrel-releasing intrauterine device (LNG-IUS) is a novel conservative surgical procedure for adenomyosis. Our study aimed to compare the efficacy of surgery with or without intraoperative placement of LNG-IUStreatment in adenomyosis.
Methods: We retrospectively studyed the medical records of adenomyosis patients who received laparoscopic adenomyomectomy from January 2017 to December 2018, including 50 patients surgery-LNG-IUS as group A and 48 patients undegoing surgery alone as group B. Demographic data, surgery-related conditions, and symptom replapse 3 years after surgery were analyzed and compared.
Results: Visual analog scale and Mansfield-Voda-Jorgensen Menstrual Bleeding Scale scores of group A at 6, 12, 24, and 36 months were significantly lower than those of group B at the corresponding points (P < .001 for both scales). Individuals in both groups showed statistically significant symptom relief. The recurrence rate in group A was significantly lower than that in group B (6.0% vs. 22.9%,P = .017).
Conclusions: Conservative surgery with intraoperative placement of LNG-IUS is more effective for adenomyosis long-term therapy and has a lower recurrence rate of adenomyosis compared to surgery alone.
Perception of aesthetic impairment in patients with systemic sclerosis using a semi-quantitative scale and association with disease characteristics.
Authors: Farhat Meryem-Maud , Guerreschi Pierre , Morell-Dubois Sandrine , Deken Valerie , Labreuche Julien , Sanges Sebastien , Sobanski Vincent , Hachulla Eric , Cottencin Olivier , Launay David 
Published: December 2022

Abstract
Background: Systemic sclerosis (SSc) is a fibrotic disease. Assessment of body image could be central in optimizing care. Yet, data are scarce. The main objective was to assess perception of aesthetic impairment using a visual aesthetic scale (AES) in patients with SSc compared to healthy subjects. Secondary objectives were to assess associations between perception of aesthetic impairment and standardized questionnaires for aesthetic impairment as well as clinical, psychological/quality of life, and functional parameters of SSc.
Methods: This study evaluated and compared perception of aesthetic impairment in two populations: patients with SSc, in a referral center at Lille Hospital, France, and healthy controls.
Results: This study included 88 patients (69 [78.4%] women) with a median age of 52 years and 88 controls (49 [55.7%] women) with a median age of 45 years. Perception of aesthetic impairment assessed using the AES was poorer in patients than in controls (3.7 ± 0.3 vs 2.8 ± 0.3, p=0.028), with statistical correlation with ASWAP, a specific aesthetic impact assessment questionnaire for patients with SSc. Patients with anxiety or depressive symptoms had significantly higher AES scores. SSc patients with facial involvement and pitting scars had a worse perception of aesthetic impairment. SSc patients have a worse perception of aesthetic impairment than healthy controls, especially in SSc patients with anxiety or depression and those with facial and hand involvement.
Conclusion: The AES appears to be an ease of use tool to evaluate body image. Correlations found with psychological and quality of life parameters reflect the importance of these parameters for body image evaluation and its complex assessment.
Trial registration: Clinical Trial NCT03271320. Registered 09 January 2017, https://www.clinicaltrials.gov/ct2/show/NCT03271320?term=NCT03271320&cntry=FR&draw=2&rank=1
Enhanced photocatalytic degradation of a cationic dye using slurry of anatase titania in a falling film reactor
Authors: Fouad Samar , Noseir Shaaban , ElShazly Yehia 
Published: December 2022

Abstract
Dyes are hazardous when it comes to dispense of the production process wastewater to the environment. The presence of trace amounts of dyes in water bodies threatens the lives of aquatic creatures and upsets the balance of the ecosystem. Moreover, the diffusion to the drinking water bodies can result in catastrophic incidents. Heterogeneous photocatalysis has shown great potential for the treatment of dyeing wastewater. Careful selection of the three main components of a photocatalytic system: irradiation source, photocatalyst and reactor configuration determines its effectiveness. In the current study, a mercury UVC lamp, along with a slurry of anatase Titania were used in a batch recirculating falling film reactor. Methylene blue was used as a model cationic dye. Photocatalyst characterization was carried out using BET, XRD and TEM analyses. Effects of the solution flow rate, initial solution pH, photocatalyst dose and initial dye concentration were studied. It was found that these factors greatly influence both the reaction rate and the removal extent. Moreover, the kinetics of the photocatalytic reaction were studied using Langmuir-Hinshelwood and Modified Freundlich kinetic models. The photocatalytic degradation of the Methylene Blue using the falling film reactor showed an outstanding performance where 98% removal was achieved.