bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation de la contamination des éléments traces métalliques dans les sédiments de la rivière N’zi, Côte d’Ivoire
Authors: Ouattara Ahbeauriet Ahmed , Sangare Naminata , N’goran Koffi Pierre dit Adama , Yao Koffi Marcellin , Trokourey Albert , Diaco Thomas 
Published: January 2022

Les éléments traces métalliques s’accumulent dans les systèmes aquatiques et peuvent dégrader la qualité des eaux et présenter une menace pour la santé humaine et la faune. Cependant peu d’étude existe sur la concentration totale des métaux dans les cours d’eau ivoiriens impactées par les activités agricoles. Pour contribuer à la mise en place d’une base de données, nous avons étudié la distribution et le niveau de contamination du Cu, Hg, Pb, Ni et Zn dans les eaux et les sédiments de la rivière N’zi. La concentration des éléments traces métalliques (Cu, Hg, Pb, Ni et Zn) ont été mesurées dans les sédiments de la rivière N’zi pour évaluer le niveau de pollution. Le degré et les sources de contamination ont été déterminés par le calcul des indices de pollution métallique : facteur de contamination (FC), indice de géoaccumulation (Igeo), facteur d’enrichissement (FE) indice global de pollution (PLI). Les valeurs de Igeo pour le Cd et le Cu ont été supérieures à 0 et les valeurs de FC pour le Cd, Cu et le Hg ont été supérieures à 1 dans la station de Moofoué, ce qui suggère que les sédiments de Moofoué sont modérément contaminés par ces éléments. Les valeurs de PLI ont montré que tous les sédiments sont non pollués. Les valeurs de FE pour le cuivre ont excédé 1,5 ce qui dénote une origine anthropique pour le Cd et le Cu.
Traces metal elements accumulate in aquatic systems and can degrade water quality and pose a threat to human health and wildlife. However, few studies exist on the total concentration of metals in ivorian rivers impacted by agricultural activities. To help set up a database, we studied the distribution and level of contamination of Cu, Hg, Pb, Ni and Zn in the waters and sediments of the N’zi River. The concentrations of the trace metals (Cu, Hg, Ni, Pb and Zn) were measured for the surface sediments of the N’zi River, Côte d’Ivoire, to evaluate the level of contamination. Sediment pollution assessment was carried out using contamination factor (CF), pollution load index (PLI), geoaccumulation index (Igeo) and enrichment factor (EF). The Igeo value for Cd and Cu were > 0 and the CF values for Cd, Cu and Hg were > 1 in sediments of the Moofoué station, which denotes a moderate contamination in these metals. The PLI indicated that all stations were no polluted. The EF value for Cd and Cu were >1.5 in the sediments, suggesting anthropogenic impact on the metal levels in the river. The concentrations of Cd and Cu are likely to result in harmful effects on sediment-dwelling organisms which are expected to occur frequently based on the comparison with sediment quality guidelines.
Effets de la consommation de petites doses de cacao sur les pressions artérielles selon leurs valeurs de base, chez des noirs africains
Authors: Siransy-Balayssac Edwige , Ouattara Soualiho , Boka Joël Michée , Wodje Mouchia Hermance , Kondo Aya Liliane , Yapo Paule-Denise , Zoh Marc Hugues , Dah Cyrille Serges , Bogui Pascal 
Published: January 2022

La baisse des pressions artérielles augmente avec la quantité de flavanols dans le cacao consommé. Or, le goût amer du cacao rend cette consommation difficile. Le but du travail a été de déterminer les effets de la consommation de petites doses de cacao selon les niveaux des pressions artérielles de sujets noirs africains. Au total, 56 noirs africains, masculins, âgés de 18 à 30 ans, ont été randomisés en 32 consommateurs de 2 g de poudre à 100% de cacao par jour et 24 témoins. Les pressions artérielles systolique (PAS) et diastolique (PAD) ont été mesurées à jeun, à J1 (sans cacao), J8, J15 et J22. Leurs variations entre J1 et les autres jours ont été comparées entre les sous-groupes d’un même groupe établis selon le niveau des PAS (<110 mmHg et ≥100 mmHg) et PAD (<75 mmHg et ≥75 mmHg) à J1. A la 1ère semaine (J8), les variations négatives (baisse) de la PAS des consommateurs ayant à J1 une PAS ≥110 mmHg ont été significativement différentes de celles des autres consommateurs (-5,5±6,2 mmHg versus 0,4±5,0 mmHg, p=0,01). Chez le sujet jeune noir africain, les petites doses de cacao favorisent une baisse plus importante des PAS les plus élevées.
The decrease in blood pressure increases with the amount of flavanols in the cocoa consumed. However, the bitter taste of cocoa makes it difficult to consume. The aim of the work was to determine the effects of small doses of cocoa intake on the blood pressure levels among black Africans. A total of 56 black African men aged 18-30, were randomized to 32 consumers of 2 g of 100% cocoa powder per day and 24 controls. The systolic (SBP) and diastolic (DBP) arterial pressures were measured on an empty stomach, on D1 (without cocoa), D8, D15, and D22. Their variations between D1 and the other days were compared between the subgroups of a group established according to the level of SBP (<110 mmHg and ≥100 mmHg) and DBP (<75 mmHg and ≥75 mmHg) on D1. At the 1st week (D8), the negative variations (decrease) in SBP of consumers with a SBP ≥110 mmHg on D1 were significantly different from those of other consumers (-5.5±6.2 mmHg versus 0.4±5.0 mmHg, p=0.01). In young black Africans, small doses of cocoa promote a greater drop in the highest SBP.
Serologic evidence of exposure to Human Immunodeficiency Virus Type 1 and Dengue Virus among patients attending diagnostic Laboratory, Lagos State, Nigeria
Authors: Ojetunde M M. , Alake M.O. , Olaniyan S.O. , Oyejobi G.K. , Olumade T.J. , Otuonye N.M. , Sule W.F. 
Published: January 2022

Reportedly, in co-infection, dengue viral (DENV) replication negatively impacts human immunodeficiency virus type 1 (HIV-1). Reports on this or on people having dual HIV-1/DENV are however, scarce in Nigeria, where both HIV-1 and DENV are endemic. As a preliminary investigation in southwest Nigeria, we hypothesized that a high proportion of individuals presented for laboratory tests have serologic evidence of dual HIV-1/DENV infection. This is a cross-sectional Research Institute-based serologic study; patients attending a specific Clinical Diagnostic Laboratory in Lagos State were enrolled. Plasma samples (n=150) of consenting asymptomatic patients were serially screened for evidence of HIV-1 antibodies using DETERMINETM and UNI-GOLDTM HIV-1/-2 rapid test kits. Only the samples (n=54) confirmed HIV-1 reactive by the latter (and some randomly selected non-reactive samples [n=37]) were tested with ELISA kit for anti-DENV immunoglobulin G (IgG) antibodies. Microsoft Excel and Statistical Package for the Social Sciences were used for statistical analysis. Some participants had detectable HIV-1/DENV antibodies with dual positivity rate of 16.5% [as group-specific point-prevalence rate]. This was independently associated (p=0.04) with marital status as participants who were neither single nor married (categorized as ‘others’) had more than 11 times (OR: 11.3) likelihood of being dual seropositive. Mono-positivity of HIV-1 antibody among the 91 participants tested for dual HIV-1/DENV seropositivity was 59.3%; corresponding rate for DENV antibody was 20.9%. As per mono-positivity rates, the likelihood of participants testing positive to HIV-1 antibody was more than 21 times (Odds ratio [OR]: 21.3) that of DENV antibody. In conclusion, 15 participants (16.5%) of this specific group had serologic evidence of dual HIV-1/DENV infection; this we considered low given the endemicity of Nigeria for both viruses. As a subpopulation with unusually high HIV-1 mono-positivity; thelow DENV mono-positivity might be responsible for the low dual HIV-1/DENV positivity.
Early mobilisation and rehabilitation in Swiss intensive care units: a cross-sectional survey
Authors: Tomonaga Yuki , Menges Dominik , Yebyo Henock G. , Fumeaux Thierry , Heise Antje , Wesch Conrad , Schwenkglenks Matthias , Puhan Milo A. 
Published: January 2022

BACKGROUND: Patients in intensive care units (ICUs) are at high risk of developing physical, functional, cognitive, and mental impairments. Early mobilisation aims to improve patient outcomes and is increasingly considered the standard of care. This survey aimed to investigate the characteristics, current use and variations of early mobilisation and rehabilitation in Swiss ICUs. METHODS: We conducted a cross-sectional survey among all ICU lead physicians, who provided data on their institutional characteristics, early mobilisation and rehabilitation practices, and their perceptions of the use and variation of early rehabilitation practices in Switzerland. RESULTS: The survey response rate was 44% (37/84). Among ICUs caring for adults (34/37), 26 were in the German-speaking region, five in the French-speaking region, and three in the Italian-speaking region. All ICUs regularly involved physiotherapy in the rehabilitation process and 50% reported having a specialised physiotherapy team. All ICUs reported performing early mobilisation, starting within the first 7 days after ICU admission. About half reported the use of a rehabilitation (45%) or early mobilisation protocol (50%). Regular, structured, interdisciplinary rounds or meetings of the ICU care team to discuss rehabilitation measures and goals for patients were stated to be held by 53%. The respondents stated that 82% of their patients received early mobilisation measures during their ICU stay. Most frequently provided mobilisation measures included passive range of motion (97%), passive chair position in bed (97%), active range of motion muscle activation and training (88%), active side to side turning (91%), sitting on the edge of the bed (94%), transfer from bed to a chair (97%), and ambulation (94%). The proportion of ICUs providing a specific early mobilisation measure, the proportion of patients receiving it, and the time dedicated to it varied across language regions, hospital types, ICU types, and ICU sizes. Almost one third of the ICU lead physicians considered early rehabilitation to be underused in their own ICU and about half considered it to be underused in Switzerland more generally. ICU lead physicians stressed lack of personnel, financial resources, and time as key causes for underuse. Moreover, they highlighted the importance of early and systematic or protocol-based rehabilitation and interprofessional approaches that are adaptive to the patients' rehabilitation needs and potential. CONCLUSION: This survey suggests that almost all ICUs in Switzerland practice some form of early mobilisation with the aim of early rehabilitation. However, the described approaches, as well as the reported use of early mobilisation measures were heterogenous across Swiss ICUs.
Role of Neutrophil Lymphocyte Ratio (NLR) in Predicting Disease Severity in Covid -19
Authors: ASİF Khadija , ABBAS Farhat 
Published: January 2022

Background: To evaluate the role of NLR as a prognostic indicator for severe COVID-19, due to its positive correlation with disease severity, easy accessibility and low cost.
Material and Methods: A multicenter retrospective observational study was conducted in COVID-19 wards of two tertiary care hospitals of Faisalabad city, Pakistan, treating COVID-19 patients between May 2021 - July 2021. A predesigned proforma was filled to collect the data. SPSS 21 was used for the statistical analysis of this research.
Results: A record of 100 COVID-19 patients admitted between May 2021 - July 2021, fulfilling the inclusion criteria was included in the study. All patients were divided into two groups. The non-severe group included 37 patients while the severe group included 63 patients. The mean age of the study population was 56 years with male predominance (63%). Overall, 50% of patients in the non-severe group and 71% in the severe group had some co-existent comorbidity. Fever and cough were the most commonly reported symptoms in both groups while shortness of breath was more widely reported in the severe group (74.2%). The mean NLR in the non-severe group was 4 as compared to 12 in the severe group.
Conclusions: Higher neutrophil lymphocyte ratio (NLR) is associated with severe COVID -19 and can be used as an effective tool to predict the progression of the non-severe disease to severe disease.
Five Years’ Experience of Multidisciplinary Approach to Chronic Inflammatory Diseases by Rheumatology, Dermatology and Gastroenterology Departments
Authors: YAĞIZ Burcu , COŞKUN Belkıs Nihan , OCAK Tugba , GÜNER Altuğ , MACUNLUOGLU Aslı , PEHLİVAN Yavuz , KIYICI Murat , YAZİCİ Serkan , BAŞKAN Emel , DALKILIÇ Hüseyin Ediz 
Published: January 2022

Introduction: Chronic inflammatory diseases (CIDs) are lifelong complex disorders that affect quality of life, and this study aimed to summarize 5 years of experience with a multidisciplinary approach for these complex diseases as a result of medical council meetings.
Methods: Hospital-based, medical records review study was conducted. A total of 45 monthly medical council meetings were held between 2014-2019 with the participation of the rheumatology, dermatology and gastroenterology departments of the same university. Patients with complex conditions that were seen in each department's own polyclinic composed the council. This study only included 308 patients referred by the rheumatology group.
Results: Females made up 66.5 % of the 308 patients. The median age was 45 (19-77). PsA (psoriatic arthritis) and other SPA (spondyloarthritis) patients composed 49.3% of the total. A total of 68.18% of the patients were presented only to consult with the dermatology department. The most common reason for presenting patients was to discuss options for treatment (41.5%). The diagnosis of psoriasis was confirmed in 48 of 67 (71.6%) patients who presented with a pre-diagnosis. The diagnosis was changed in 34.74% of the patients, whereas the diagnosis became completely different in 11.36% of the patients.
Conclusions: Many patients with challenging diagnosis and treatment processes are encountered in daily practice. The combination of different disciplines makes it possible to provide more rapid and effective solutions. In this study, we aimed to emphasize the increasing importance of such multidisciplinary approaches
Relationship Between Familial Mediterranean Fever and Other Rheumatic Diseases: Coincidence or Coexistence?
Authors: TEZCAN Dilek , GÜLCEMAL Semral , LİMON Muhammet , KÖREZ Muslu Kazım , YİLMAZ Sema 
Published: January 2022

Background: Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease affecting mainly the ethnic groups of the Mediterranean basin. It has been reported that it can coexist with various systemic inflammatory diseases. This study aimed to obtain information on rheumatic diseases that accompany FMF and evaluate the relation between FMF and such diseases.
Methods: Eighty-four patients diagnosed with FMF and have rheumatic disease comorbidity in the rheumatology clinic between January 2018 - March 2020 were included in this study.
Results: The most common accompanying rheumatic disease was spondyloarthritis with 36 patients. Vasculitides was the second common disease accompanying FMF with 22, followed by connective tissue disease in 13, rheumatoid arthritis in 5, juvenile idiopathic arthritis in 4, gout in 3, and hidradenitis suppurativa in 1 patients. The most common MEFV mutation observed was M694V. There was no significant difference in demographic characteristics and clinical manifestations between M694V mutation types.
Conclusions: In this study, the relation between FMF and various rheumatic diseases was determined. Two new conditions, eosinophilic granulomatous polyangiitis, and scleroderma were detected. The associations may be just coincidental or an extension of the common underlying pathology. To be aware of this association is important to early diagnosis and appropriate treatment.
Clinical, radiological and laboratory features and treatment responses of COVID-19 diseases in pregnant women
Authors: ŞİMŞEK Abdullah , TAŞBAŞ Esin , KOCA Nizameddin , ÜSTÜNDAĞ Yasemin , YORULMAZ GÖKTAŞ Sibel , DİKİŞ Özlem , DÜLGER Seyhan , KARAOĞLU Ahmet , SOYLU Uğur 
Published: January 2022

Background: SARS-CoV-2 is more contagious than other viruses among populations. Pregnant women
are particularly susceptible to respiratory pathogens and severe pneumonia.
Material and Methods: Thirty-two pregnant women who were diagnosed with COVID-19 disease by PCR test in our hospital between March 2020 and June 2020 were included in this study. Patients’ complaints, comorbid disorders, general physical conditions, radiological, laboratory characteristics, treatment results, and maternal and fetus health were recorded retrospectively.
Results: The mean age of the patients was 26.6 years. Pregnancy-induced hypertension was evident in 2 patients (6.2%), preeclampsia in 1 patient (3.1%), asthma in 1 patient (3.1%). Mostly detected complaints were cough (34.4%) and fatigue (31.3%). The most frequent abnormal laboratory findings were high fibrinogen level (80.9%), high D-dimer level (71.4%), high CRP level (58.1%). Lymphopenia was found in 15.6% of patients. The maternal and fetal mortality rate was 0%. The rate of improvement in laboratory values in response to the treatment was as follows respectively; sodium (92.3%), lymphocyte count (80%), LDH (62.5%), CRP (61.1%), D-dimer (25%). None of the patients developed spontaneous abortion. Cesarean delivery was performed in 15.6% of patients. 5 newborns were negative for the COVID-19 PCR test two times.
Conclusions: Mostly detected complaints in pregnancy patients with COVID-19 disease were cough and fatigue. While evaluating the treatment response, the improvement in sodium level may be more valuable than the improvement in acute phase reactants. The prognosis was quite good in mothers and children treated for this disease. The vertical transition of the disease could not be demonstrated.
Outcome in patients with peripheral T-cell lymphoma treated with pralatrexate, single center experience
Authors: AKDENİZ Aydan , YILMAZ Nurcan , KOYUNCU Mahmut Bakır , TOMBAK Anıl 
Published: January 2022

Background: Peripheral T-cell lymphoma (PTCL) accounts for 10-15% of all non-Hodgkin lymphomas. Five-year overall survival is very poor in all subtypes except in ALK positive anaplastic large cell lymphomas (ALCL). Patients in relapsed-refractory (RR) setting, treatment options are very limited, particularly in patients with poor performance or advanced age. Pralatrexate has been shown to improve remission and survival rates in RR PTCL. We aimed to evaluate the response rates, efficacy and adverse event profile of pralatrexate used in RR PTCL in our center.
Material and Methods: Patients followed in hematology department of Mersin University with the diagnosis of RRPTCL and treated with pralatrexate were included in study. Their demographical and clinical data were documented. Response to treatment with pralatrexate was evaluated.
Results: Median follow up time was 14 months and mean age at diagnosis was 50.6 (±17.9) in totally 11 patients. Patients received median 2 cycles of pralatrexate. Six patients were refractory to treatment while 5 patients achieved at least partial remission.
Conclusions: PTCL has the worst prognosis among all types of lymphomas. Cure rates are still low and new therapeutic options are needed.
TÖRÖKORSZÁG ÉS AZ EURÓPAI UNIÓ KAPCSOLATAINAK FEJLŐDÉSE ÉS JÖVŐJE
Authors: Tőkés Tibor , György Zoltán 
Published: January 2022

Törökország és az Európai Unió kapcsolatai az EU jogelődjeinek kialakulásáig vezethetők vissza. A kapcsolatok hosszú távon tekintve pozitív irányúak, hiszen fokozatos közeledés figyelhető meg a felek között. Rövidtávon e viszonyban azonban extrém mértékű kilengések is tapasztalhatóak. A múltban a fokozatos közeledést katonai puccsok és inváziók szakították meg. Probléma merült fel számos kérdés eltérő megközelítése miatt is, mely tekintetben a szereplők különböző nézőpontból vizsgálták Törökország jogállását, és azt, hogy európai országnak tekinthető-e egyáltalán. Napjainkban Törökország közel-keleti regionális politikai érdekei miatt saját Európai Uniós csatlakozását háttérbe szorítja. Ezzel a magatartással Törökország jelentős feszültséget idézhet elő a szomszédos Európai Uniós országokkal kapcsolatban, vagy olyan kétes kimenetelű konfliktusokba kapcsolódhat be, melyekkel rontja saját európai megítélését. Az országban elindult társadalmi változások előkészíthetik azt a lehetőséget, hogy Törökország belátható időn belül belépjen az Európai Unióba. Ehhez azonban jelen állás szerint évtizedek kellenek. A felek nem fogják a gazdasági kapcsolataikat felmondani, változás politikai szinten lehetséges.
Strategi Pemasaran Global di Pasar Indonesia
Authors: Hasibuan Anni Zuhro Syafrida , Aslami Nuri 
Published: January 2022

This review expects to get a worldwide advertising system in the Indonesian market for Indonesian organizations. The examination strategy utilized is expressive investigation technique. The blend of key showcasing variation and standard promoting system is worldwide advertising that is as per economic situations in Indonesia. It tends to be perceived that globalization is another test for organizations in executing advertising systems. Because of globalization, organizations are needed to rival elite organizations that have huge capital and more excellent items. In Indonesia, it turns into the objective market for worldwide organizations to expand their benefits, while Indonesian organizations lose in the opposition.
Keywords: global marketing strategy, globalization
Pengaruh Modal dan Tenaga Kerja terhadap Upah Kerja Pengrajin Rotan di Kecamatan Medan Petisah Kota Medan Sumatera Utara
Authors: Puspa Meilinda , Arif Muhammad , Imsar Imsar 
Published: January 2022

This review plans to decide if there is an impact of capital and work at the same time on the pay of rattan specialists in Medan Petisah region and the impact of capital and work somewhat on the pay of rattan experts in Medan Petisah sub-area. The object of this exploration is rattan experts in Medan Petisah sub-area. This review utilizes information assortment strategies polls, perceptions, and meetings. The strategy utilized in this exploration is a quantitative strategy with various straight relapse procedures. The insightful strategy utilized is illustrative examination, old style supposition test and relapse condition test with view of capital (X1), work (X2), and pay (Y). The consequences of this review show that the variable capital has a positive and critical impact on pay, implying that the higher the capital of the rattan specialists, the pay will increment, as well as the other way around. Work variable has a positive and critical impact on pay, implying that the more specialists, the more pay will increment, as well as the other way around. This implies that the capital and work factors all the while have a positive and huge impact on the pay of rattan specialists in Medan Petisah sub-region.
Keywords : Capital, Labor, Income