bluuebunny/crossref_metadata_2025_split huggingface dataset:
Weight Gain and Adipose Tissue Accumulation in Diabetic and Prediabetic Rats Fed with Palm Olein enriched High Fat Diet
Authors: Sim Xuan-Yi , Ahmad Waqas , Lee Yan-Fen , Teh Ying-Hui , Murugaiyah Vikneswaran , Ibrahim Baharudin , Greimel Peter , Gam Lay-Harn 
Published: April 2022

Diabetic is known to be the main non-commutable public health concern. In this study, we evaluated the relationship between diet, body weight and accumulation of adipose tissue in healthy, diabetic and prediabetic rats. Physiologically, adipose tissue plays a central role in lipid and glucose metabolisms. Therefore, accumulation of adipose tissue in diabetic and prediabetic may lead to others non-commutable diseases. The rats in control, diabetic and prediabetic groups were fed with normal and high fat diets for 6 consecutive weeks, while the rats in 4 sub-groups of diabetic and prediabetic groups also received metformin, a common drug to control diabetes. The results indicated that in diabetic rats, a small increase of food calories by high fat diet caused a significant gained in body weight and a significant increase in adipose tissue accumulation with or without metformin treatment, however in prediabetic rats, rats with metformin treatment shown to be beneficial in maintaining body weight and adipose accumulation. The data of the study imply that balance diet at high calories should be practiced by patients as high fat diet with similar calories can caused a significant health deterioration to the patients in term of body weight gained and adipose tissue accumulation.
Assessment of Cereals for Fungal Contaminants and Presence of Aflatoxins from Two Major Markets in Kaduna Metropolis
Authors: Abdulrahman Idris , Danbaba Amina Aliyu , Uba Garba 
Published: April 2022

Aflatoxins are mycotoxins produced by fungi of the genus Aspergillus that contaminate food products such as cereals leading to serious health and economic consequences. In order to assess the level of fungal contaminants and the presence of aflatoxins in such products, five (5) different cereal samples comprising of rice, maize, millet, wheat and sorghum were purchased each from two major markets within Kaduna metropolis. The samples were assessed for fungal contaminants using ten-fold serial dilution and cultured appropriate dilutions using pour-plate technique. Aflatoxins were detected using Enzyme-linked Immunosorbent Assay (ELISA). The results obtained revealed viable fungal counts ranging from 3 x 102 to 3.2 x 103 cfu/g. The fungal contaminants identified from the samples include Aspergillus flavus, Aspergillus niger, and Aspergillus fumigatus. The aflatoxins detected from the samples were within the range of 0.3 to 0.6 part per billion (ppb) which is less than the maximum value (10ppb) recommended by regulatory agencies such as NAFDAC. This indicates that the level of aflatoxin in the samples has insignificant risks to consumers. However, the fungal contamination is an indication of high-level contamination of the cereals, the key producers of aflatoxins. The contamination of such products by fungi should be a source of worry and necessitates the need for proper personal and environmental hygiene in the processing of cereals.
Diagnosis dan Tata Laksana Dismenore Primer
Authors: Anggraini Meilisva Audila , Lasiaprillianty Intan Wahyu , Danianto Ario 
Published: April 2022

<p>Dismenore dibagi atas jenis primer (tanpa kondisi patologik pelvis) dan sekunder (dengan kondisi patologik pelvis). Diagnosis dismenore primer berdasarkan anamnesis dan pemeriksaan fisik yang teliti. Penanganan di fasilitas kesehatan primer adalah diagnosis dan tata laksana dismenore primer dan menyingkirkan kecurigaan dismenore sekunder. Obat anti-inflamasi non-steroid (OAINS) dan terapi hormonal merupakan terapi lini pertama untuk dismenore primer.</p><p>Dysmenorrhea is categorized into primary (without pelvic pathologic conditions) and secondary (with pelvic pathologic conditions) forms. Diagnosis of primary dysmenorrhea is based on a complete history and physical examination. Management in primary health facilities is to diagnose and manage primary dysmenorrhea and to rule out secondary dysmenorrhea. Non-steroid anti-inflammatory drugs (NSAIDs) and hormonal therapy are first-line therapy for primary dysmenorrhea.</p><p> </p>
The Role of Conventional Chest X-Ray in Detection and Evaluation of Long COVID-19
Authors: - Andri , Amanda Yuanita 
Published: April 2022

<p>A 52-year-old woman came to ER with shortness of breath, fever, and cough with oxygen saturation of 80% on room air. The COVID-19 PCR test was positive. CXR showed it infiltrates ground-glass opacities in both lungs and cardiomegaly. Chest X-ray at discharge from the hospital showed decreased infiltrate and fibrosis in two lung. She came to the ER 4 days later with worsened shortness of breath. CXR showed diffuse infiltrates in both lungs and cardiomegaly. Discussion: COVID-19 patients can develop long-term sequelae and complications (long COVID-19). Although CT is now considered the primary investigation for COVID-19, CXR is still valid for detecting and monitoring its progression. Conclusion: CXR is useful for detecting and monitoring the rapid advancement of lung abnormalities in long COVID-19.</p><p>Wanita 52 tahun datang ke IGD dengan sesak napas, demam, batuk; dengan saturasi oksigen 80% udara ruangan. Tes PCR COVID-19 positif. Rontgen toraks menunjukkan infiltrat di kedua lapangan paru, ground glass opacities, dan kardiomegali. Rontgen toraks saat keluar rumah sakit menunjukkan penurunan gambaran infiltrat dan fibrosis pada dua lapangan paru. Empat hari setelah keluar rumah sakit pasien kembali sesak napas. Rontgen toraks menunjukkan infiltrat difus dikedua paru dan kardiomegali. Diskusi: Pasien COVID-19 dapat mengalami sekuele jangka panjang dan komplikasi, disebut long COVID-19. Walaupun CT-scan menjadi pendeteksi utama COVID-19, rontgen toraks masih bermanfaat untuk memantau progresi sindrom tersebut.</p><p> </p>
Kvalitet integriranosti Islamske vjeronauke u školski odgojni kontekst /Quality of Integration of Islamic Confessional Education in Educational Context
Authors: Pehlić Izet , Grabus Emina 
Published: April 2022

The aim of this research was to establish the quality of integration of Islamic confessional education in educational context of schools; to diagnose manners and ways for reaching a higher level of quality of integration of Islamic confessional education in the educational context and also to propose measures and steps necessary for reaching higher level of its integration in the context of primary schools. The methods used for this were theoretical analysis and descriptive-analytical survey. The techniques used were attitude surveys of teachers of confessional education and teachers of other subjects with a questionnaire. A questionnaire was designed for the purpose of this research to examine the quality of integration of the subject into the integral educational curriculum of schools. The sample comprised of 104 Islamic confessional teachers and 100 teachers of other subjects in Zenica-Doboj Canton. The results of the research revealed that there is a statistically relevant difference in attitudes of Islamic confessional education teachers and teachers of other subjects. Confessional education teachers, more than other teachers, give more importance to the hidden curriculum, which is an indicator of real integration. They highlight the contribution of their subject to the development of integrated curriculum, point out the importance of framework for development of their subject curriculum as a basis for its integration into the school curriculum. They also establish greater inter-subject correlation with all educational segments; dedicate attention to teamwork and inclusion serving the development of integrated curriculum. They see assessment as a segment of evaluation that contributes to integration of confessional education into school’s curriculum, highlight the contribution of confessional education curriculum to development of pupil’s personality as well as the fact that the textbook for confessional education contributes more to integration of confessional curriculum than other textbooks and course curricula they are based on. Finally confessional education curriculum is largely integrated in primary school curriculum and contributes to integrated school curriculum more than the curricula of other subjects.
Institucije islamske civilizacije / Institutions of Islamic Civilization
Authors: Maslo Amer 
Published: April 2022

Institucije islamske civilizacije – izabrani članci iz Türkiye Diyanet Vakfı İslâm Ansiklopedisi, Ahmet Alibašić, Munir Mujić (ur.), Sarajevo: Čentar za napredne studije, 2017, str. 712, ISBN 978-9958-022-50-0.
EKSPLORASI PEMBELAJARAN MATEMATIKA TINGKAT SD DI ERA PANDEMI PADA DUSUN JOMBOK DESA SEMBUNGIN KECAMATAN BANCAR KABUPATEN TUBAN
Authors: Junianti Ika Wulan , Mahanani Prima Ayu Rizqi 
Published: April 2022

Era pandemi mengakibatkan perubahan pembelajaran dari luring ke daring hal ini tentunya akan menimbulkan tantangan baru dalam pembelajaran khususnya pelajaran matematika yang terdapat rumus-rumus di dalamnya, jika dalam pembelajaran matematika siswa hanya diberikan tugas-tugas tanpa dijelaskan maka akan menimbulkan masalah baru karena tidak semua orang tua menguasai matematika dan teknologi, khususnya orang tua santri TPQ Ar-Rohman di Dusun Jombok Desa Sembungin Kecamatan Bancar Kabupaten Tuban untuk itu dengan dilakukannya penelitian ini diharapkan dapat ditemukan solusi dari kendala pembelajaran daring matematika tingkat SD di dusun Jombok melalui penelitian kualitatif deskriptif dengan subjek santri TPQ Ar-Rohman beserta orang tuanya, setelah dilakukan penelitian ternyata terjadi kendala dalam pembelajaran daring yaitu guru hanya memberikan tugas tanpa dijelaskan materinya, orang tua kurang memahami materi, rasa jenuh ketika belajar, dan orang tua kurang menguasai teknologi yang ada, untuk itu untuk dibuatlah sebuah bimbingan belajar untuk SD dengan model pembelajaran tutor teman sebaya dan ternyata dengan adanya bimbingan belajar yang dibuat anak-anak lebih antusias untuk belajar matematika.
Pola Peresepan Penggunaan Obat Antihipertensi Di UPTD Puskesmas Airmadidi
Authors: Polopadang Yuliana , Mongi Jeane , Maarisit Wilmar , Karauwan Ferdy 
Published: March 2022

Tingginya angka kejadian hipertensi berdampak terhadap meningkatnya morbiditas dan mortalitas masyarakat. Salah satu cara untuk mengontrol hipertensi adalah pemberian terapi farmakologis antihipertensi yang tepat. Penelitian ini bertujuan untuk mengetahui pola peresepan penggunaan obat antihipertensi di UPTD Puskesmas Airmadidi Minahasa Utara. Data diambil secara retrospektif dan dianalisa secara deskriptif dari buku register dan rekam medis pasien periode januari – juni 2019. Hasil penelitian menunjukkan bahwa dari 559 pasien hipertensi paling banyak terjadi pada perempuan sebesar 375 ( 67,08 % ) pasien dan pada laki – laki sebesar 184 ( 32,92 % ). Penderita hipertensi terbanyak terdapat pada kelompok usia 60 – 69 tahun sebanyak 243 ( 43,47 % ) pasien, diikuti oleh kelompok usia 50 – 59 tahun sebanyak 135 ( 24,15 % ) pasien dan terendah pada kelompok usia 80 -89 tahun sebanyak 4 ( 0,72 % ) pasien. Pemberian terapi farmakologi yang paling banyak adalah monoterapi dibandingkan politerapi. Golongan obat yang paling banyak digunakan adalah ACE-I yaitu captopril dan untuk politerapi golongan obat yang paling banyak digunakan adalah CCB dan ACE –I yaitu amlodipin dan captopril. . Berdasarkan derajat hipertensi, sebagian besar monoterpi diberikan pada pasien dengan hipertensi stadium I.
Ser profesor-tutor de matemáticas de la UNED en tiempos del COVID-19: del confinamiento a la innovación
Authors: Medina-Albós Adoración 
Published: April 2022

En este artículo presento mi experiencia personal como profesora-tutora de la asignatura Matemáticas Aplicadas a las Ciencias Sociales del Curso de Acceso a la Universidad en el Centro Asociado de la Seu d’Urgell durante los dos cursos académicos marcados por la pandemia COVID-19: el curso 2019-20 y el curso actual, 2020-21. Tras hacer una tarea de reflexión acerca de mi labor tutorial, llevada a cabo de forma improvisada durante el confinamiento y la posterior evolución de esta el curso siguiente, analizo qué debería mejorar de cara al próximo curso académico, 2021-22, que, pese a la campaña de vacunación masiva, parece que estará también marcado por la incertidumbre de una pandemia que todavía no ha acabado.
Abstract
In this article I present my personal experience as a teacher-tutor of the subject Applied Mathematics to Social Sciences of the University Access Course at the Associated Center of La Seu d'Urgell during the two academic years marked by the COVID-19 pandemic: the course 2019-20 and the current course, 2020-21. After making a task of reflection about my tutorial work, carried out in an improvised way during the confinement and the subsequent evolution of this the following course, I analyze what I should improve for the next academic year, 2021-22, which, despite the massive vaccination campaign, it seems that it will also be marked by the uncertainty of a pandemic that has not yet ended.
Autoevaluaciones temporizadas como punto de partida para el trabajo en línea
Authors: Delgado Pineda Miguel , Estrada López Beatriz 
Published: April 2022

Este trabajo trata los contenidos expuestos en la conferencia presentada en el congreso eMath-2020 en noviembre de 2020. Se presentan las experiencias de autoevaluación realizadas en el curso 2019-2020. Además, se muestran los diseños, sus aplicaciones y los resultados obtenidos en dicho curso académico. Estas experiencias se desarrollaron utilizando los cursos virtuales donde se realiza la mayor parte de la actividad docente con los estudiantes de la UNED. La información contenida en este trabajo es relativa a dos asignaturas; una del grado en Matemáticas y otra de grado en Ciencias Ambientales. Estas se imparten en la modalidad de la Enseñanza a Distancia en la UNED.
Abstract
This paper deals with the contents exposed in the conference presented at the eMath-2020 congress in November 2020. It presents the experiences of self-assessment carried out in the course 2019-2020. In addition, the designs, their applications and the results obtained in academia are presented. Said experiences were developed using the virtual courses of assistance to UNED students. The information contained in this work is related to two subjects; one from the degree in Mathematics and the other from the degree in Environmental Sciences. These are taught in the modality of Distance Learning at UNED.
Agricultural Information Gathering and Use among Smallholders’ Sugarcane Farmers during the COVID-19 Pandemic in Tanzania: A Case of Kilosa District
Authors: Joseph Gwimile Nuru , Yongsheng Zhang 
Published: April 2022

Aims: The agricultural sector is considered the backbone of Tanzania's economy. Information accessibility to farmers depends on the situation and the available sources. This article aims at attempting to understand the agricultural information gathering and use among smallholders’ sugarcane farmers during the covid-19 pandemic in Tanzania: a case of Kilosa district.
Research Methods: In this study, we conducted field surveys among farmers, and of the out in Ruaha, Kidodi, and Kidogobasi villages in Kilosa district, in Morogoro region, Tanzania. A total number of 4776 key informants were engaged in the study to examine information accessibility to farmers depending on the situation and the available sources.
Results: The study found out that agricultural information smallholder farmers needed for sugarcane farming was information on markets 84%, sugarcane payment per ton 74%, and information on the harvest and fertilizers application 72%. We observed that the main source of agricultural information was fellow farmers and agricultural information officers and Radio. We discovered that, before the outbreak of the COVID-19 pandemic, the majority (89.7%) accessed agricultural information from their fellow farmers, (71.3%) of respondents said that agricultural extension officer was their preferred source. It was revealed that the majority (83.0%) of the smallholder sugarcane farmers revealed that a limited number of agricultural extension officers was the main challenge, (72.4%) of the respondents said that a limited number of seminar-workshop and agricultural training incomplete statement. The findings adds up on the insights on the utilization of agricultural information during pandemic.
Conclusion: It can be concluded that agricultural information accessibility is important to smallholder farmers’ sugarcane production; furthermore, agricultural extension officers are a significant role in farmers’ productivity even amid the COVID-19 pandemic.
Assessing the Impact of Gas Flaring on Tea Plants in the South of Kothaloni OCS in the District of Dibrugarh, Assam, India
Authors: Phukan Ripsita , Sahewalla Indra Prasad , Bora Diganta Kumar 
Published: April 2022

Effect of gas flaring on physiology and growth of tea plants was done by using Randomized Complete Block Design (RCBD) and analysis was done accommodating two seasons and five levels of distances during September 2019-March 2020. Plant samples were collected from (40-50) metres, (50-60) metres, (60-70) metres, (70-80) metres and control site (150-160) metres away from the tea garden situated south of kothaloni OCS in rainy and autumn seasons. The experimental plot was laid out at a distance of 40 metres away from the flare pit. The mean value of plant parameters namely relative turgidity, tea leaf area ,specific leaf weight, stomatal count, caffeine content, chlorophyll content, polyphenol content and plucking point density were decreased near the gas flaring while mean value of water saturation deficit of tea leaves recorded highest at distances closest to the flaring site.
GxE Interactions Elucidated by AMMI, BLUP and Non Parametric Measures of Wheat Genotypes by Evaluated in North Eastern Plains Zone
Authors: Verma Ajay , Pratap Singh Gyanendra 
Published: April 2022

Highly significant effects of environments, GxE interactions and genotypes showed by AMMI analysis with respective contributions 53.2%, 24.9%, 3.5% towards total sum of squares. Interaction Principal Components axes (IPCA) values recommended the general adaptations of the genotype. IPCA-1 scores pointed for G4, G2, G7 while IPCA-2 selected G10, G3, G9 genotypes. Both ASV & ASV1 utilized 46.2% of interaction sum of squares recommended G4, G1, G12 wheat genotypes. Based on 97.8% of interactions sum of squares MASV1 measures identified G7, G3, G5 whereas MASV measure settled for G7, G3, G9. BLUP-based measures HMGV, RPGV and HMRPGV identified G2, G8, G1 genotypes. Non parametric composite measures viz NPi (1) observed suitability of G2, G5, G7 whereas NPi(2), for G10, G7, G9 while NPi(3) identified G10, G9,G7 genotypes of choice. NPi(4) found suitability of G10, G7, G9 genotypes. Biplot analysis of considered measures had seen about 65.4% of the total variation explained by first two significant Principal Components. NPi(2) , NPi(3) , NPi(4) formed a cluster adjacent to cluster of ASV, ASV1, MASV, MASV1, Si7 BLStd, BLCV measures. Small cluster of IPC4, IPC3 placed near to cluster of BLUP based measures. ASV and ASV1 showed moderate to strong positive correlations values while MASV and MASV1 showed moderate strong positive correlation values with Si1, Si2, Si3 Si4, Si5, Si6, Si7 NPi(1) , NPi(2) ,NPi(3), NPi(4) measures. Non parametric measures would be useful to explain the GxE interaction while augmented with other measures.
A Study of Corneal Thickness in Type 2 Diabetes Mellitus with and without Diabetic Retinopathy
Authors: Ramani Rashmi , Banait Shashank 
Published: April 2022

Background: It is essential to assess the corneal thickness in diabetes patient.
Introduction: diabetes mellitus is a major cause of blindness throughout the worldDiabetic retinopathy is the most importance given on day to day basics studies especially for ophthalmologist studied indicators in eye. However, functional oddities have been recognised in cornea too like changes in central corneal thickness.
Objectives: 1. To estimate the central corneal thickness (CCT) of type 2 diabetes mellitus patients without diabetic retinopathy age/sex matched normal people. 2. To measure central corneal thickness (CCT) of type 2 diabetes mellitus patient with diabetic retinopathy with age/ sex matched normal person.
Methods: This is a hospital based case control study.
Expected Results: The central corneal thickness is more in type 2 diabetes patients than non-diabetic individual.
An Integrated Phenotypic and Genotypic Approach Reveals a High‐Risk Subtype Association for EBF3 Missense Variants Affecting the Zinc Finger Domain
Authors: Deisseroth Cole A. , Lerma Vanesa C. , Magyar Christina L. , Pfliger Jessica Mae , Nayak Aarushi , Bliss Nathan D. , LeMaire Ashley W. , Narayanan Vinodh , Balak Christopher , Zanni Ginevra , Valente Enza Maria , Bertini Enrico , Benke Paul J. , Wangler Michael F. , Chao Hsiao‐Tuan 
Published: March 2022

ObjectiveCollier/Olf/EBF (COE) transcription factors have distinct expression patterns in the developing and mature nervous system. To date, a neurological disease association has been conclusively established for only the Early B‐cell Factor‐3 (EBF3) COE family member through the identification of heterozygous loss‐of‐function variants in individuals with autism spectrum/neurodevelopmental disorders (NDD). Here, we identify a symptom severity risk association with missense variants primarily disrupting the zinc finger domain (ZNF) in EBF3‐related NDD.MethodsA phenotypic assessment of 41 individuals was combined with a literature meta‐analysis for a total of 83 individuals diagnosed with EBF3‐related NDD. Quantitative diagnostic phenotypic and symptom severity scales were developed to compare EBF3 variant type and location to identify genotype–phenotype correlations. To stratify the effects of EBF3 variants disrupting either the DNA‐binding domain (DBD) or the ZNF, we used in vivo fruit fly UAS‐GAL4 expression and in vitro luciferase assays.ResultsWe show that patient symptom severity correlates with EBF3 missense variants perturbing the ZNF, which is a key protein domain required for stabilizing the interaction between EBF3 and the target DNA sequence. We found that ZNF‐associated variants failed to restore viability in the fruit fly and impaired transcriptional activation. However, the recurrent variant EBF3 p.Arg209Trp in the DBD is capable of partially rescuing viability in the fly and preserved transcriptional activation.InterpretationWe describe a symptom severity risk association with ZNF perturbations and EBF3 loss‐of‐function in the largest reported cohort to date of EBF3‐related NDD patients. This analysis should have potential predictive clinical value for newly identified patients with EBF3 gene variants. ANN NEUROL 2022;92:138–153