bluuebunny/crossref_metadata_2025_split huggingface dataset:
First report about a cerebrospinal nematode infection in an alpaca (Vicugna pacos)
Authors: Mathias Michaely L. , Hoeltig Doris , Ganter Martin , Rentería-Solís Zaida , Bauer Christian , Baumgärtner Wolfgang , Wohlsein Peter 
Published: September 2022

AbstractThe number of New World camelids in European farms is rising and thus, the need for veterinary care towards these animals arises. However, veterinary care requires sophisticated knowledge on disease and pathogen occurrence within New World camelids. Here, an alpaca cria with neurological signs was admitted to the veterinary clinic. Although the animal was treated with antibiotics, vitamins and dexamethason, it refused to drink milk and the clinical status worsened. After euthanasia, necropsy and histopathological examination were carried out and revealed intracerebral nematode larvae. The morphology of these larvae strongly suggests them to be Baylisascaris procyonis, a parasite of raccoons. The extended history revealed that a fully grown raccoon was living within farm enclosures, suggesting an infection of the alpaca and the development of a cerebrospinal larva migrans. This zoonotic disease is characterized by aberrant larval migration that typically shows extraintestinal migration in dead-end hosts. The aim of this report is to sensitize practical colleagues towards this rare, but occasionally fatal infection in New World camelids while familiarizing diagnostic pathologists with the morphological characteristics of this disease.
Intradiploic Epidermoid Cyst of the Posterior Fossa – Case Report and Review of the Literature
Authors: Januário Gonçalo , Cunha Bruno , Cellini Ludovica , Novais Gonçalo 
Published: September 2022

AbstractIntracranial epidermoid cysts represent ∼ 0.2 to 1.8% of all intracranial tumors. These tumors are most frequently encountered in the cerebellar pontine angle or in the parasellar region. Rarely, they arise from the cranial diploe, being able to affect every flat bone of the cranium.We report a case of a 63-year-old male who presented with progressively worsening headache and vertigo with 6 months of evolution. Neuroimaging identified a probable occipital intradiploic epidermoid cyst with mass effect on the cerebellar hemispheres. This lesion was approached using a suboccipital craniotomy, followed by total resection of the tumor and cranioplasty with titanium plate placement. The histological evaluation confirmed the diagnosis of intraosseous epidermoid cyst. The patient had a successful recovery, without complications or neurologic dysfunction.Being benign lesions, commonly remaining asymptomatic and rarely presenting as a bony lump in the skull bone, it could be straightforward to assume a conservative management with planned follow-up. On the other side, a more aggressive strategy with surgical excision has been advocated, especially in lesions that tend to enlarge and erode the cranial bone with possible consequent epidural extension and mass effect symptoms. A preoperative diagnosis is extremely helpful in proper surgical planning. Diffusion weighted imaging facilitates a straightforward diagnosis.As was observed in our case, the largest reviews on intradiploic epidermoids available in the literature mostly demonstrated a benign clinical course. However, malignant transformation can occur. Some patients develop permanent neurologic deficits from mass effect or tumor infiltration. However, surgical approach of the tumor is curative in most cases. Nonetheless, from our experience, it is important to maintain clinical and imaging follow-up with regular monitoring to prevent possible tumor recurrences.
A university-wide survey of caregiving students in the US: Individual differences and associations with emotional and academic adjustment
Authors: Armstrong-Carter Emma , Panter A. T. , Hutson Bryant , Olson Elizabeth A. 
Published: September 2022

AbstractThe United States (US) does not formally count, recognize, or support students in higher education who are caregivers, unlike England and Australia. This mixed-methods study presents results from a new survey of caregiving undergraduate and graduate students at a large university in the US. Students (N = 7592; 62.7% White, 69.9% women) reported their caregiving responsibilities, depression, and anxiety, which were linked to administrative records of financial aid, part-time status, and academic grades (GPA). A small but noteworthy portion of students identified as caregivers (5.6%, N = 427), either for someone who was chronically ill or elderly (3.2%; N = 239) or for a minor under age 18 (2.9%; N = 227). Caregiving students were disproportionately women, graduate students, enrolled part-time, and receiving financial aid. Further, caregivers for the chronically ill or elderly (but not for a minor) faced heightened emotional and academic risk. Specifically, caregiving for 3–5 days per week was associated with lower GPA, and caregiving more hours per day was linked to greater anxiety and depressive symptoms. US universities should identify the needs of caregiving students and design policies to mitigate emotional and academic risk.
A general method for rapid synthesis of refractory carbides by low-pressure carbothermal shock reduction
Authors: Han Ye-Chuang , Liu Meng-Li , Sun Li , Li Shuxing , Li Gen , Song Wei-Shen , Wang Yan-Jie , Nan Zi-Ang , Ding Song-Yuan , Liao Hong-Gang , Yao Yonggang , Stucky Galen D. , Fan Feng Ru , Tian Zhong-Qun 
Published: September 2022

Refractory carbides are attractive candidates for support materials in heterogeneous catalysis because of their high thermal, chemical, and mechanical stability. However, the industrial applications of refractory carbides, especially silicon carbide (SiC), are greatly hampered by their low surface area and harsh synthetic conditions, typically have a very limited surface area (<200 m
2
g
−1
), and are prepared in a high-temperature environment (>1,400 °C) that lasts for several or even tens of hours. Based on Le Chatelier’s principle, we theoretically proposed and experimentally verified that a low-pressure carbothermal reduction (CR) strategy was capable of synthesizing high–surface area SiC (569.9 m
2
g
−1
) at a lower temperature and a faster rate (∼1,300 °C, 50 Pa, 30 s). Such high–surface area SiC possesses excellent thermal stability and antioxidant capacity since it maintained stability under a water-saturated airflow at 650 °C for 100 h. Furthermore, we demonstrated the feasibility of our strategy for scale-up production of high–surface area SiC (460.6 m
2
g
−1
), with a yield larger than 12 g in one experiment, by virtue of an industrial viable vacuum sintering furnace. Importantly, our strategy is also applicable to the rapid synthesis of refractory metal carbides (NbC, Mo
2
C, TaC, WC) and even their emerging high-entropy carbides (VNbMoTaWC
5
, TiVNbTaWC
5
). Therefore, our low-pressure CR method provides an alternative strategy, not merely limited to temperature and time items, to regulate the synthesis and facilitate the upcoming industrial applications of carbide-based advanced functional materials.
Heterozygous LRP1 deficiency causes developmental dysplasia of the hip by impairing triradiate chondrocytes differentiation due to inhibition of autophagy
Authors: Yan Wenjin , Zheng Liming , Xu Xingquan , Hao Zheng , Zhang Yibo , Lu Jun , Sun Ziying , Dai Jin , Shi Dongquan , Guo Baosheng , Jiang Qing 
Published: September 2022

Developmental dysplasia of the hip (DDH) is one of the most common congenital skeletal malformations; however, its etiology remains unclear. Here, we conducted whole-exome sequencing in eight DDH families followed by targeted sequencing of 68 sporadic DDH patients. We identified likely pathogenic variants in the
LRP1
(low-density lipoprotein receptor-related protein 1) gene in two families and seven unrelated patients. All patients harboring the
LRP1
variants presented a typical DDH phenotype. The heterozygous
Lrp1
knockout (KO) mouse (
Lrp1
+/−
) showed phenotypes recapitulating the human DDH phenotypes, indicating
Lrp1
loss of function causes DDH.
Lrp1
knockin mice with a missense variant corresponding to a human variant identified in DDH (

Lrp1
R1783W

) also presented DDH phenotypes, which were milder in heterozygotes and severer in homozygotes than those of the
Lrp1
KO mouse. The timing of triradiate cartilage development was brought forward 1 or 2 wk earlier in the LRP-deficient mice, which leads to malformation of the acetabulum and femoral head. Furthermore,
Lrp1
deficiency caused a significant decrease of chondrogenic ability in vitro. During the chondrogenic induction of mice bone marrow stem cells and ATDC5 (an inducible chondrogenic cell line), Lrp1 deficiency caused decreased autophagy levels with significant β-catenin up-regulation and suppression of chondrocyte marker genes. The expression of chondrocyte markers was rescued by PNU-74654 (a β-catenin antagonist) in an shRNA-Lrp1–expressed ATDC5 cell. Our study reveals a critical role of LRP1 in the etiology and pathogenesis of DDH, opening an avenue for its treatment.
Topological crossing in the misfolded
Tetrahymena
ribozyme resolved by cryo-EM
Authors: Li Shanshan , Palo Michael Z. , Pintilie Grigore , Zhang Xiaojing , Su Zhaoming , Kappel Kalli , Chiu Wah , Zhang Kaiming , Das Rhiju 
Published: September 2022

The
Tetrahymena
group I intron has been a key system in the understanding of RNA folding and misfolding. The molecule folds into a long-lived misfolded intermediate (M)
in vitro
, which has been known to form extensive native-like secondary and tertiary structures but is separated by an unknown kinetic barrier from the native state (N). Here, we used cryogenic electron microscopy (cryo-EM) to resolve misfolded structures of the
Tetrahymena
L-21 ScaI ribozyme. Maps of three M substates (M1, M2, M3) and one N state were achieved from a single specimen with overall resolutions of 3.5 Å, 3.8 Å, 4.0 Å, and 3.0 Å, respectively. Comparisons of the structures reveal that all the M substates are highly similar to N, except for rotation of a core helix P7 that harbors the ribozyme’s guanosine binding site and the crossing of the strands J7/3 and J8/7 that connect P7 to the other elements in the ribozyme core. This topological difference between the M substates and N state explains the failure of 5′-splice site substrate docking in M, supports a topological isomer model for the slow refolding of M to N due to a trapped strand crossing, and suggests pathways for M-to-N refolding.
I hear you, I see you, I know who you are
Authors: Beaulieu Suzie , Reinke Kristin , Šebková Adéla , French Leif Michael 
Published: September 2022

Abstract
The present study investigated the attitudes of long-time residents of Quebec City towards French Lx economic
immigrants settling into their community. We evaluated the speech of four linguistic groups (English, Spanish, Mandarin and Farsi)
using the verbal-guise methodology. Listeners were presented with 10 audio-only stimuli (1 male and 1 female speakers from each
group and 2 distractors) and 10 combined audio-visual stimuli (1 male and 1 female Quebec French speakers associated with
photographs from our target language groups). After hearing each excerpt, listeners rated the speakers on their perceived
characteristics. Results showed that the combined stimuli were evaluated more favorably than the audio-only stimuli. We also found
that female voices were significantly better evaluated than those of men. Last, listeners showed preferences towards Spanish and
Farsi groups over English and Mandarin, and specifically towards female voices. The evaluations thus seem to reflect past and
present stereotypes circulating in the community.
Proficiency in a second language influences processing of print-to-sound mappings
Authors: Botezatu Mona Roxana , Misra Maya , Kroll Judith F. 
Published: September 2022

Abstract
A hallmark of word naming in deep orthographies, effects of spelling-sound regularity and consistency are
considered to reach stability in adulthood. We investigated whether these effects were modulated by second language (L2)
proficiency in native English and native Spanish speakers. Participants named English, Spanish and language-ambiguous words, but
only the English words were used in the analysis. Participants in each group named English words with irregular-inconsistent
mappings (e.g., PINT) more slowly and less accurately than words with regular-consistent mappings (e.g., GATE). Higher English
proficiency reduced the magnitude of the regularity-consistency effect in both groups. Critically, native English speakers
revealed a U-shaped relationship between L2-Spanish proficiency and the regularity-consistency effect on naming latencies. The
current findings add to a growing body of literature that considers the boundaries within which L2 proficiency can influence
native language (L1) performance. Results suggest that L2 proficiency may destabilize a fundamental aspect of L1 literacy, the
computation of phonology from text, which is known as a highly stable psycholinguistic effect. This suggests that the language
system is dynamic, remaining plastic in early adulthood.
Role of pressure on electronic, magnetic and structural properties at iron’s Curie temperature: a DFT + DMFT study
Authors: Gendron F , Cliche N , Amadon B 
Published: September 2022

Abstract
We use the combination of density functional theory and dynamical mean-field theory to compute the Curie temperature of the iron body-centered cubic α phase and probe its pressure dependence. Our calculations reveal that

T

C

shows a decrease which is very weak over a domain of pressures that is much larger than the stability domain of the α phase. This is consistent with the experimental results. We highlight the importance of the Hund’s coupling J not only on the electronic and magnetic properties but also on the structural properties. Lastly, we analyze the electronic and magnetic properties under pressure and discuss the evolution of magnetic moments in both phases in relation to the change of Curie temperature.
Current and future constraints on cosmology and modified gravitational wave friction from binary black holes
Authors: Leyde K. , Mastrogiovanni S. , Steer D.A. , Chassande-Mottin E. , Karathanasis C. 
Published: September 2022

Abstract
Gravitational wave (GW) standard sirens are well-established probes with which one can measure cosmological parameters, and are complementary to other probes like the cosmic microwave background (CMB) or supernovae standard candles. Here we focus on dark GW sirens, specifically binary black holes (BBHs) for which there is only GW data. Our approach relies on the assumption of a source frame mass model for the BBH distribution, and we consider four models that are representative of the BBH population observed so far. In addition to inferring cosmological and mass model parameters, we use dark sirens to test modified gravity theories. These theories often predict different GW propagation equations on cosmological scales, leading to a different GW luminosity distance which in some cases can be parametrized by variables Ξ0 and n. General relativity (GR) corresponds to Ξ0 = 1. We perform a joint estimate of the population parameters governing mass, redshift, the variables characterizing the cosmology, and the modified GW luminosity distance. We use data from the third LIGO-Virgo-KAGRA observation run (O3) and find — for the four mass models and for three signal-to-noise ratio (SNR) cuts of 10, 11, 12 — that GR is consistently the preferred model to describe all observed BBH GW signals to date. Furthermore, all modified gravity parameters have posteriors that are compatible with the values predicted by GR at the 90% confidence interval (CI). We then focus on future observation runs O4 and O5, and for simplicity consider one specific mass model. We show that there are strong correlations between cosmological, astrophysical and modified gravity parameters. If GR is the correct theory of gravity, and assuming narrow priors on the cosmological parameters, we forecast an uncertainty of the modified gravity parameter Ξ0 of 51% with ∼ 90 detections at O4-like sensitivities, and Ξ0 of 20% with an additional ∼ 400 detections at O5-like sensitivity. We also consider how these forecasts depend on the current uncertainties of BBHs population distributions.
Preheating in Palatini Higgs inflation on the lattice
Authors: Dux F. , Florio A. , Klarić J. , Shkerin A. , Timiryasov I. 
Published: September 2022

Abstract
We study preheating following Higgs inflation in the Palatini formulation of gravity. We
numerically evolve perturbations of the radial mode of the Higgs field and that of three scalars
modeling the gauge bosons. We compare the two non-perturbative mechanisms of growth of
excitations — parametric resonance and tachyonic instability — and confirm that the latter plays
the dominant role. Our results provide further evidence that preheating in Palatini Higgs
inflation happens within a single oscillation of the Higgs field about the bottom of its
potential, consistent with the approximation of an instantaneous preheating.
Preparation of soap using a steam extraction process from leaves of Azadirachta indica, Ocimum basilicum, Hibiscus-rosa-sinensis Flowers, Acalypha indica, and Aloe barbadensis Leaflets
Authors: Indirani C , Meenambika K , Indhumathy D , Kavinkumar V S 
Published: September 2022

AbstractSoaps are used widely by humans in many aspects. Exclusively, the emergence of the SARS-Cov-2 virus made people wash their hands frequently to disinfect the virus to prevent virus infection. Soaps made of herbals possess constituents that goodness the skin as well to rejuvenate the mind and body factors. Dried leaves of Basil, Neem and Acalypha Indica, Aloe vera, and Hibiscus flower are used here to prepare homemade soap. The steam distillation process is an imperative process by which the oils are used from raw materials like dried leaves for the preparation of soaps. Extracts obtained from the herbal plants are used as additives in the preparation of soap that would be added besides the lye and other constituents. Lye preferred here is Sodium Hydroxide (NaOH) and the cast shapes utilized here in determining the soap shape are Elliptic and Rectangle. pH value, the total fatty matter is determined using respective methodologies, and the materials used in the preparation of soap are estimated using the accessible software called SoapCalc Recipe Calculator. Soaps made using the mentioned ingredients are safe and robust for cleaning the skin and hands.
Applications for Green Technology Practices in Analyzing the Edge Detection Techniques on Digital Image Processing by using MATLAB
Authors: Ravikumar R. , Arulmozhi V. 
Published: September 2022

Abstract
Increasing awareness and growing focus on environmental issues such as climate change, energy use, and the loss of non-renewable resources have created a great need for research that provides possible solutions to these problems. Environmental science and engineering research continue to play an important role in revealing new “green” future opportunities. Digital Image Processing plays a major role in contributing to its relevant research works under these Environmental and Green Technologies. By applying tools related to Environment technology this Digital Image Processing produces numerous applications. In such cases, Edges provide an important dynamic change in digital image processing. It is a process of finding and finding edges with sharp changes made by the power of its images. This is the best way to get an accurate edge in good shape and also different edge finders will work in better different conditions. Different methods of edge detection were compared comparatively to determine which method was most suitable for obtaining edges without any noise conditions. Here, the three types of edges have horizontal, vertical and diagonal edges. In this paper, we review the different editing methods and compare different identification methods, advantages, and disadvantages. Implementation is done using MATLAB. A sudden change of discontinuity is evident in the image.
An experimental study of solar receiver under cloudy weather conditions
Authors: Havaldar Sanjay N , Kulkarni Kaustubh G , Dhokane Nilesh T , Nimbalkar Shrikant D 
Published: September 2022

Abstract
The performance of the central solar receiver should be properly examined for an effective design of a solar power or solar heating system. The performance of solar receiver is affected by three parameters. These are the amount of solar radiations, the state of the heating medium and the temperature of the surrounding air. Also, while evaluating the performance of a solar receiver, the ambient weather conditions should be taken into account. As a result, when a large amount of direct light strikes a solar receiver, the power generated increases as well. In contrast, as the amount of direct light falling on the solar receiver diminishes, so does the amount of electricity generated. As a result, it is generally understood that on sunny days, the performance of the central solar receiver will be higher, while on overcast days, the performance will be reduced. The solar receiver collects heat from diffused or reflecting light (when the sun is obscured by clouds) and absorbs reflective light from glossy or light-colored surfaces. The experimental results reveal that solar radiation collection performance is dependent on climatic circumstances; thus, when installing a solar receiver, it should be suitable for the specific region depending on weather conditions.
Obesity: technology, exercise and diet
Authors: Jaramillo Roger , Villao Alex , Merchán Diana , Jaramillo Jorge 
Published: September 2022

Abstract
Use of technology to accompany the treatment of obesity and exercise routine has become an ideal complement to carry historical data that are representative to measure the evolution of this disease. A bibliographic analysis of some studies was applied where it has successfully contributed to the use of APPs that are cornering the market because they not only measure the steps an individual takes, but also the calories consumed versus calories burned. APPs are a tool or support, but obesity is a complex disease that requires another type of support, not only an APP; Additionally, climate change affects food security, which causes the increase of this disease.
Blue green algal farming revolution: An eco-friendly top-up step for Agribusiness advancements
Authors: Sharma Parvati , Kumari Ankur , Bhardwaj Anuradha , Poonia Asha , Yashpal  
Published: September 2022

Abstract

Global population growth rate accelerating earth ecosystem disturbance and increasing resource scarcity, malnutrition and poverty. These events challenge socio-economic development of each country and obligate scientific communities to develop such novel approaches to overcome this burden, which not only provide a healthy diet but also engage people in setting up their own business. Therefore, microalgae Spirulina is the one of the emerging food source with rich protein content and other nutritional components in adequate amount with diverse health benefits. The small scale investments in microalgae biomass production, familiarizing nutraceutical values and convert in consumable forms is the interesting agribusiness with diversified profits and popularization. Spirulina production strategies can be conventional and low-cost effective technologies. These techniques also help in designing new innovative possibilities in modifications and enhancements in the existing agriculture products processing strategies for their better use in different industries. Although most of communities are aware about agribusiness strategies of Spirulina but still it is in one the demanding and upcoming bright sector. This article reveals the methods of mass production of Spirulina and their significant role in agriculture as well as industrial.