bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genotipos de frijol (Phaseolus vulgaris) común con resistencia a BGYMV en Cuba
Authors: Morales-Soto Arianna , Lamz-Piedra Alexis , Chang-Sidorchuk Lidia , Martínez-Zubiaur Yamila 
Published: June 2022

Introducción. El mosaico amarillo dorado del frijol, causado por el begomovirus bean golden yellow mosaic virus (BGYMV), es uno de los factores que limitan la producción de frijol (Phaseolus vulgaris L.) en Cuba. El mejoramiento genético para la resistencia a este virus es una de las estrategias más efectivas para el control de la enfermedad. Objetivo. Seleccionar genotipos de frijol común con resistencia a BGYMV y con estabilidad del rendimiento de grano. Materiales y métodos. Se sembraron en Mayabeque, Cuba (en un diseño de bloques al azar), en tres épocas (enero 2019, octubre 2019 y enero 2020), veintidós genotipos de frijol (dieciséis líneas avanzadas donadas por la Escuela Agrícola de Zamorano, Honduras, el cultivar comercial ‘Cuba Cueto 25-9N’, los testigos resistente y susceptible ‘Delicia 364’ y ‘Velasco Largo, respectivamente). Luego se identificó la presencia del gen bgm-1, que confiere resistencia a BGYMV, a partir de la presencia del marcador SCAR SR2. Resultados. La evaluación de la reacción en campo permitió la identificación de diecinueve genotipos con respuesta resistente ante la infección natural del BGYMV. Se identificaron dieciséis genotipos de frijol común con la presencia del marcador SCAR SR2 y diecisiete genotipos que mostraron un comportamiento estable del rendimiento del grano durante las épocas de evaluación, que pueden tener utilidad para el mejoramiento genético del cultivo de frijol. Conclusión. Los resultados permitieron identificar diecinueve genotipos con resistencia a BGYMV. Los diecisiete genotipos resistentes a BGYMV con el marcador SCAR SR2 y estables, podrían ser incluidos en el banco de germoplasma de frijol y como progenitores en programas de cruzamientos, así como en ensayos regionales de rendimiento en otros ambientes donde se cultiva frijol.
Do evaluation and self-identification relate to self-reported and actual social media use?
Authors: Cathelyn Femke , Van Dessel Pieter , Cummins Jamie , De Houwer Jan 
Published: June 2022

Abstract

Background and aims
Social media use can sometimes become excessive and damaging. To deal with this issue, scholars and practitioners have called for the development of measures that predict social media use. The current studies test the utility of evaluation and self-identification measures for predicting social media use.

Method
Study 1 examined the relation between evaluation (n = 58) and self-identification (n = 56) measures on the one hand and several self-report measures of social media use on the other hand. Study 2 examined whether the main results of Study 1 could be replicated and whether evaluation (n = 68) and self-identification (n = 48) also relate to actual social media use. We probed evaluation and self-identification using implicit and explicit measures.

Results
Explicit evaluation and self-identification measures significantly correlated with several of the self-report measures of social media. Explicit evaluation also significantly correlated with several indices of actual social media use. Implicit measures did not relate to social media use.

Discussion and conclusions
The current results suggest that researchers and practitioners could benefit from using explicit evaluation and self-identification measures when predicting social media use, especially an evaluation measure since this measure also seems to relate to actual social media use. Study 2 was one of the first to test the ecological validity of social media use measures. Although implicit measures could provide benefits for predicting social media use, the current studies did not show evidence for their predictive utility.
The effect of the 12-week judo physical activity program on the self-esteem of secondary school students during the COVID-19 period
Authors: Efek Engin , Eryiğit Hakan 
Published: June 2022

Background and Study Aim. During the COVID-19 period, participation in physical activity decreased, and at the same time, many psychological problems occurred in children and adolescents. Therefore, this study examines the impact of secondary school students’ participation in regular exercise on their self-esteem.
Material and Methods. The research was carried out with an experimental method and sequential design. The study, carried out in 2 sessions, started with the first measurement in November 2021 and ended with the last measurement in January 2022. 46 volunteer students forming the study sample were divided into experimental and control groups. Students in both groups completed the ‘Personal Information Form’ and the ‘Coopersmith Self-Esteem Inventory’ in the first week and the end of the 12th week. Statistical Package for Social Sciences (SPSS) 17.0 was used for data analysis. First, a descriptive statistical test was conducted to indicate the socio-demographic characteristics of the participants. Then, normality tests (Skewness and Kurtosis) were applied to determine whether the data showed normal distribution, and it was determined that the data showed normal distribution. Finally, the independent sample t-test and Paired Samples t-test were applied because the data met the assumption of normal distribution. The significance level was determined as p<0.05.
Results. A statistically significant difference was found between the self-esteem values of the experimental group before the physical activity program and after the exercise sessions. There was no significant difference in the self-esteem levels of the control group pre-test and post-test.
Conclusions. In conclusion, this study reveals that participation in 12 weeks of regular exercise significantly increases middle school students’ self-esteem.
Biotransformation of sesaminol triglycoside by intestinal microflora of swine supplemented with probiotic or antibiotic diet
Authors: Jan Kuo-Ching , Wang Tzu-Yi , Hwang Lucy Sun , Gavahian Mohsen 
Published: June 2022

Lignans, found throughout the plant kingdom, are complex diphenolic chemicals that act as phytoestrogens. The main lignan component in sesame flour is sesaminol triglucoside (STG). In vivo, STG is converted into antioxidant sesaminol, mammalian lignans enterodiol, and enterolactone. Thus, use of antibiotics may impact the conversion of lignans to enterolactone. The present study investigated the metabolism of STG by microorganisms in swine-fed diets supplemented with either probiotics or antibiotics. It was observed that microorganisms from swine-fed probiotics helped with hydrolyzing the glucose unit of STG and generated metabolite 2-hydroxymethyl sesaminol- tetrahydrofuran (ST-2) as compared to antibiotic diet. It was also observed that bacteria that converted sesaminol to ST-2 were oxygen-sensitive and it was hypothesized that these were anaerobes. While Lactobacillus and Bifidobacterium were more prevalent in probiotic-fed swine feces, both groups of swine had a healthy mix of helpful and detrimental bacteria. All selective investigated microorganisms (Lactobacillus, Bifidobacterium, and Clostridium perfringens) could hydrolyze the glucose unit of STG; however, lactic acid bacteria contributed least. In conclusion, the bacteria found in the feces of swine-fed probiotics had a greater ability to digest STG. It can be concluded that the biotransformation of STG could be attributable to anaerobes, but Lactobacillus and Bifidobacterium could balance intestinal flora.
Founding Fathers (in a Tailings Pond)
Authors: Dennis Unrau Melanie 
Published: June 2022

This speculative essay uses an imaginary (and non-existent) comic to call a tar-sands industry founder who may have thought of himself as a goose back to Fort McMurray to see how waterfowl fare in tailings ponds. It treats S.C. Ells (1878-1971), an early-20th-century Canadian Department of Mines engineer who was also an amateur writer and illustrator, as a colonial founder not only of the tar-sands industry but also of literary and visual representations of the industry and the Athabasca region. Drawing inspiration from artist and former tar-sands worker Kate Beaton’s “Founding Fathers” comics, it compares the linkages between humans and waterfowl in Ells’s works and in Beaton’s 2014 webcomic “Ducks.” By doing so, it takes Ells on a time-travelling adventure and homecoming tour in the petromodern dystopia that has become his legacy.
El significado del trabajo en distintas generaciones de argentinos
Authors: Rubio Agustín , Botero Camila , Delfino Gisela , Boso Roxana 
Published: June 2022

Teniendo en cuenta el modelo propuesto por Meaning of Working (MOW-International Research Team, 1987), se exploró el significado del trabajo en cuanto a la centralidad y la identificación con los roles en distintas generaciones. Se evaluó la variable género al considerarla relevante al momento de conocer diferencias que podrían surgir entre los dos grupos. Se trató de un estudio descriptivo correlacional, de diseño no experimental, transversal, con una muestra compuesta por 187 personas de ambos géneros, con edades entre 18 y 72 años (M = 39.44, DE = 16.46) residentes de la zona metropolitana de Buenos Aires. Se hallaron diferencias intergeneracionales significativas en la centralidad absoluta y relativa, pero no en cuanto a la identificación con los roles. A su vez, los resultados obtenidos reportaron diferencias significativas en cómo tienden los hombres y las mujeres a significar el trabajo relativo y cómo se identifican con los roles.
Inventarisasi dan Identifikasi Serangga Pada Tanaman Rockmelon (Cucumis melo Var Reticulatus)
Authors: Rahmi Rias , Orbani Rosa Herlda , Marsuni Yusriadi 
Published: June 2022

Penelitian ini bertujuan untuk mengetahui jenis-jenis serangga pada pertanaman rockmelon (Cucumis melo var reticulatus). Penelitian ini dikerjakan dari bulan Maret - Agustus 2020, pada fase vegetatif dan generative, Penelitian dilaksanakan di lahan pertanaman rockmelon di Daerah Jalan Aneka Tambang Kelurahan Loktabat Selatan Kota Banjarbaru. dan di Laboratorium Entomologi Fakultas Pertanian Universitas Lambung Mangkurat, Banjarbaru. Dengan menggunakan metode survey eksploratif. Pengambilan sampel dilakukan dengan menggunakan perangkap lalat buah, perangkap likat kuning, pengambilan secara langsung menggunakan tangan dan jaring serangga. Serangga yang diperoleh diletakan didalam botol koleksi yang telah berisi alkohol 70%. Hasil akhir menunjukkan serangga tertangkap di fase vegetatif ada 216 ekor, terdiri atas 10 ordo, 10 famili. sedangkan pada fase generatif serangga yang tertangkap terdiri dari 10 ordo dan 23 famili dengan jumlah populasi serangga lebih besar yaitu 666 ekor. Status serangga yang paling dominan pada pertanaman rockmelon adalah sebagai hama, dengan persentase 56%, terdiri 7 ordo, 19 spesies serta 14 famili, serangga predator sebanyak 26%, 4 ordo, 9 spesies dan 6 famili. Polinator sebanyak 18 %, 3 ordo, 6 spesies dan 4 famili.
Study protocol of a multiphase optimization strategy trial for delivery of smoking cessation treatment in lung cancer screening settings
Authors: Ostroff Jamie , Shelley Donna , Chichester Lou-Anne , King Jennifer C. , Li Yuelin , Schofield Elizabeth , Ciupek Andrew , Criswell Angela , Acharya Rashmi , Banerjee Smita C. , Elkin Elena , Lynch Kathleen , Weiner Bryan J. , Orlow Irene , Martin Chloé M. , Chan Sharon , Frederico Victoria , Camille Phillip , Holland Susan , Kenney Jessica 
Published: June 2022

Abstract
Background
There is widespread agreement that integration of cessation services in lung cancer screening (LCS) is essential for achieving the full benefits of LCS with low-dose computed tomography (LDCT). There is a formidable knowledge gap about how to best design feasible, effective and scalable cessation services in LCS facilities. A collective of NCI-funded clinical trials addressing this gap is the SCALE (Smoking Cessation at Lung Examination) Collaboration.
Methods
The Cessation and Screening to Save Lives (CASTL) trial seeks to advance knowledge about the reach, effectiveness, and implementation of tobacco treatment in lung cancer screening. We describe the rationale, design, evaluation plan and interventions tested in this multiphase optimization strategy trial (MOST). A total of 1,152 screening-eligible current smokers are being recruited from 18 LCS sites (n = 64/site) in both academic and community settings. Participants receive enhanced standard care (cessation advice and referral to the national Quitline) and are randomized to receive additional tobacco treatment components (motivational counseling, nicotine replacement patches/lozenges, message framing). The primary outcome is biochemically-validated, abstinence at 6 months follow-up. Secondary outcomes are self-reported smoking abstinence, quit attempts, and smoking reduction at 3- and 6-months. Guided by the Implementation Outcomes Framework (IOF), our evaluation includes measurement of implementation processes (reach, fidelity, acceptability, appropriateness, sustainability and cost).
Discussion
We will identify effective treatment components for delivery by LCS sites. The findings will guide assembly of an optimized smoking cessation package that achieves superior cessation outcomes. Future trials can examine strategies for wider implementation of tobacco treatment in LDCT-LCS sites.
Trial Registration:
Clinicaltrials.gov: NCT03315910. October 20, 2017
A study protocol for a double-blind randomised placebo-controlled trial evaluating the efficacy of carrageenan nasal and throat spray for COVID-19 prophylaxis – ICE COVID
Authors: Jessop Zita , Gibson John , Lim Jia , Jovic Thomas H , Combellack Emman , Dobbs Thomas , Carter Kym , Hiles Stephen , Islam Saiful , Healy Brendan , Humpreys Ioan , Eccles Ron , Hutchings Hayley , Whitaker Iain 
Published: June 2022

Abstract
Introduction:At present, vaccines form the only mode of prophylaxis against COVID-19. The time needed to achieve mass global vaccination and the emergence of new variants warrants continued research into other COVID-19 prevention strategies. The severity of COVID-19 infection is thought to be associated with the initial viral load and for infection to occur, viruses including SARS-CoV-2 must first penetrate the respiratory mucus and attach to the host cell surface receptors. Carrageenan, a sulphated polysaccharide extracted from red edible seaweed, has shown efficacy against a wide range of viruses in clinical trials through prevention of viral entry into respiratory host cells. Carrageenan has also demonstrated in-vitro activity against SARS-CoV-2. This clinical trial was designed to investigate the efficacy of carrageenan nasal and throat sprays in reducing the rate and severity of COVID-19 infection. If proven effective, the self-administered prophylactic spray would have wider utility for key workers and the general population.Methods and analysis:A single centre, randomised, double-blinded, placebo-controlled phase III trial was designed. Participants randomised in a 1:1 allocation to either the treatment arm, verum Coldamaris plus (1.2 mg iota-carrageenan (Carragelose®), 0.4 mg kappa-carrageenan, 0.5% sodium chloride and purified water) or placebo arm, Coldamaris sine (0.5% sodium chloride) spray applied daily to their nose and throat for 8 weeks, while completing a daily symptom tracker questionnaire for a total of 10 weeks.Primary outcome: Acquisition of COVID-19 infection as confirmed by positive PCR swab taken at symptom onset or seroconversion during the study. Secondary outcomes include symptom type, severity and duration, subsequent familial/household COVID-19 infection and infection with non-COVID-19 upper respiratory tract infections. A within-trial economic evaluation will be undertaken, with effects expressed as quality-adjusted life years.Hypothesis: That carrageenan spray will reduce SARS-CoV-2 attachment to the naso- and oropharyngeal mucosal epithelial cells thus reducing the effective viral infective dose preventing COVID19 infection and reducing disease severity where infection is not prevented.Ethics and dissemination:Ethics approval was obtained from Research Ethics Committee 6 South Wales (REC Reference 20/WA/0298; IRAS 283187) on the 18th November 2020. The results will be submitted for publication in a peer-reviewed journal.Trial registration number: NCT04590365; registered on ClinicalTrials.gov (NCT04590365) on the 19th October 2020.
Existence of Intuitionistic Fuzzy Additive Definite Integral by an Optimized Subtraction Operation
Authors: Khan Mohd Shoaib , Panday Aditya Narayan 
Published: June 2022

Abstract
The induced aggregation operator from the intuitionistic additive definite integral is an important tool to aggregate information. But, before utilizing any measure, it is essential to examine their existence over the given dataset . In this paper, we intend to examine the existence of intuitionistic fuzzy additive definite integral and hence their induced aggregation operator with respect to the new subtraction operation $\ominus^{'}$ . To do so, we first discussed the new subtraction operation $\ominus^{'}$ against the old subtraction operation $\ominus$ over some counter-examples. It is observed that there are some cases in which the old operation $\ominus$ is not defined. Therefore, to ensure the existence of the additive definite integral in a more general setting, we proved some lemma and theorems by using the new subtraction operation and function of bounded variation.
The Incidence Rate and Economic Burden of Catheter-related Bloodstream Infection (CRBSI): a Single center, Retrospective Study
Authors: Zhang Yibo , Wang Yichen , Shi Dake , Wang Qun , Xu Shirui , Cao Zhujun , Ai Yaping , Chen Erzhen , Ni Yuxing , XU Yumin 
Published: June 2022

Abstract
BackgroundIndwelling central venous catheters (CVCs) have the potential to lead to catheter related blood stream infection (CRBSI). We report the findings of a single center, retrospective matched case-control study that assessed the incidence rate of CRBSI in ICUs and attributable length of stay (LOS), costs among patients with CRBSI in ICU in Shanghai, China.MethodsThe study was carried out in several ICUs, with a total of 2300 beds of 3 tertiary-level hospital affiliated to Shanghai Jiao Tong University. The Department of Infection Control performs routinely surveillance for CRBSI on ten different ICUs.ResultsThe CRBSI incidence rate of hematology ICU, which was the highest, was 4.43 per 1000 CVC-days. 51 patients were successfully matched with control patients. The average cost in the CRBSI group was $ 67,923 which was significantly higher (P < 0.001) than that in the control group. The total average cost attributable to CRBSI was $33, 227.ConclusionsThe cost of antibiotics was closely related to the incidence of CRBSI.
Enriched H3K27Me3 on BMP4 Suppresses the Osteoblastic Differentiation Potential of BMSCs in Diabetes Mellitus
Authors: Tang Yu , Hu Yun , Ding Xiaoqian , Luo Dan , Li Caiyu , Daraqel Baraa , Zheng Leilei 
Published: June 2022

Abstract
Background Diabetes mellitus has been widely acknowledged to have a negative effect on the osteoblastic differentiation of bone marrow-derived mesenchymal stem cells (BMSCs). However, the underlying epigenetic mechanisms associated with this process remain to be elucidated. The goal of the present study was to investigate the effect of diabetes mellitus on the osteoblastic differentiation of BMSCs and assess the role of histone methylation in the observed phenomena.Methods The effect of diabetes mellitus was simulated by isolating BMSCs from diabetic rats and culturing them with glucose and AGEs.Results The osteoblastic differentiation ability of BMSCs was shown to be decreased in diabetes mellitus, as indicated by alkaline phosphatase activity and the mRNA levels of osteoblast-related genes. Furthermore, diabetes mellitus caused an increased expression of the histone methylase EZH2 and the levels of H3K27Me3 and decreased the expression of the histone demethylase KDM6B, as demonstrated by qRT-PCR and western blotting. Furthermore, immunofluorescence staining suggested that both EZH2 and H3K27Me3 were primarily localized in the nucleus. In addition, chromatin immunoprecipitation assays indicated an increased presence of H3K27Me3 on the promoter region of the BMP4 gene. Conclusion We demonstrated that the osteoblastic differentiation of BMSCs is dramatically reduced in diabetes mellitus. In addition, upregulation of EZH2 expression and downregulation of KDM6B expression may not be enough to eliminate transcriptional repression mediated by H3K27Me3 on the promoter region of the BMP4 gene during the osteoblastic differentiation of BMSCs in diabetes mellitus.
Physical therapy interventions in schizophrenia compared to normal sedentary adults: different effects of aerobic and functional programs over posture and flexibility- controlled trial
Authors: Cristiano VIVIANE Batista , Szortyka Michele Fonseca , Belmonte-de-Abreu Paulo 
Published: June 2022

Abstract
Background: Schizophrenia has disabling effects over mental and physical integrity involving changes in posture and flexibility, which reduce mobility, autonomy, and quality of life. Physical activity has been tested with uncertain effects in schizophrenia, mostly due to trial design, methodology, comparison groups, intervention length, and attrition. Inconsistency led to poor dissemination of active interventions in this population, which may benefit these individuals’ health. Objective: To evaluate the response of two different protocols: Aerobic and Functional exercises, in two groups of sedentary adults—patients with the diagnosis of schizophrenia and healthy controls.Methods: A clinical trial of two standardized physical interventions in adults diagnosed with schizophrenia and healthy controls. Posture was assessed by digital photogrammetry with the aid of a software and the flexibility by the Wells Fargo’s Test. Results: A total of 38 individuals completed the intervention, with 24 in Aerobic group and 14 in Functional group. The groups were homogeneous for gender, weight, and body mass index, with small differences in age and height. Posture and Flexibility changed according to group and intervention. In this study, guided physical activity improved posture and flexibility in both groups, with higher effect of the Functional protocol than the Aerobic protocol in cases and controls. Conclusions: Despite a preliminary and relatively small sample size, the study evidences the feasibility and clinical utility of physical intervention in schizophrenia. Additional data about specific adaptations in schizophrenia are needed to improve outcomes, such as individualized assistance, support, instructions and intensity. Trial registration: Clinical trial registration: Brazilian Registry of Clinical Trials (ReBEC) under No. RBR-2h2hjy; date: 09/29/2020, retrospectively registered (https://ensaiosclinicos.gov.br/rg/RBR-2h2hjy).
Non symmetry of the function ζ(s)/s
Authors: OUKIL Walid 
Published: June 2022

Abstract
We prove that ζ(s) s ̸= ζ(1−s) 1−s for every ℜ(s) ∈ (0, 1 2 ) and ℑ(s) > 0, where ζ is the Riemann Zeta function. In the end of the paper, we give a discussion about the Riemann hypothesis.