bluuebunny/crossref_metadata_2025_split huggingface dataset:
Utilization of Tannin Based Adhesive from Mahogany (Swietenia Mahagony) Extract Bark for Composite Product
Authors: Lest Andi Sri Rahayu Diza , Santoso Adi , Saad Sahriyanti , Arisandi Heru , Taskirawati Ira 
Published: November 2022

AbstractThe aim of this study was to determined the quality of mahogany (Swietenia mahagony) tannin extract as an adhesive for plywood. The mahogany tannin extract was copolymerized with phenol and formaldehyde became TPF adhesive. Then, the plywood was made from mangium (Acacia mangium) and sengon (Paraseriathes Falcataria) with dimensions 30 × 30 × 0.6 (cm3) in the length, width, and thickness, respectively. Pressing was carried out using the cold press method for 11 minutes and then followed by the hot press method for 10 minutes at a temperature of 110oC with a specific pressure of 1.47 MPa. Phenol formaldehyde and urea formaldehyde adhesives were used as a comparison and 5 replicates were made for each plywood. The physical and mechanical were tested according to JAS 233:2003. The result showed that TPF had an equal quality with the synthetic adhesive in dry conditions. Moreover, all of plywood from sengon wood categorized as F**** the lowest and the best.
Improved extreme learning machine based on adaptive dual-strategy optimization algorithm and its application
Authors: Yuan Gao , Liang Zhang , Jiawei Zhou , Wei Yuan , Yangjun Qiu 
Published: November 2022

Abstract
Aiming at the problem of low accuracy and unstable prediction results caused by the random connection weight threshold between the input layer and the hidden layer of extreme learning machine (ELM). An adaptive dual-strategy improved pelican optimization algorithm (IPOA) -ELM regression prediction model is proposed. Firstly, the pelican optimization algorithm (POA) is improved by the Logistic-Tent chaotic map, improved convergence factor by adaptive double strategy method and reverse learning strategy. Then, the performance of IPOA is verified by multiple groups of multi-dimensional single-peak and multi-peak test functions. The test results show that IPOA has better accuracy, stability, and robustness than POA, butterfly optimization algorithm (BOA), cuckoo algorithm (CS), grey wolf algorithm (GWO), particle swarm optimization algorithm (PSO), genetic algorithm (GA) and mouse swarm optimization algorithm (RSO). Finally, IPOA is applied to optimize ELM, and the performance of the IPOA-ELM model is verified by three engineering data sets. The simulation results show that the convergence accuracy, stability, and robustness of the IPOA-ELM model are better than those of the POA-ELM and ELM models.
High inflammation level is essential to cerebral microbleed in the prediction of large artery atherosclerotic outcomes
Authors: Hou Duanlu , Lu Ying , Li Zhixin , Zeng Yanwei , Tang Zhouping , Yang Xiaobo , Wu Danhong , Dong Qiang , Han Xiang , Zhang Jun , Tang Yuping 
Published: November 2022

Abstract
Background and Purpose: Cerebral small vessel damages and large artery atherosclerotic (LAA) stroke share many risk factors, such as inflammation, but little attention has been paid to the relationship between cerebral small vessel damages with inflammation in predicting large artery atherosclerotic stroke outcomes.
Methods: We consecutively enrolled participants with LAA stroke and collected their baseline and follow-up data, especially the imaging markers of cerebral small vessel disease and C reactive protein (CRP), and neutrophil-to-lymphocyte ratio (NLR) levels. The primary outcomes were LAA stroke outcomes at 3-month and 1-year, the secondary outcomes poststroke hemorrhagic transformation, infarction recurrence, and mortality.
Results: 864 participants were included to the final analysis. We found that only cerebral microbleed (CMB) with numbers greater than 5 can predict 3-month (p < 0.001) and 1-year (p < 0.01) outcomes in LAA stroke, furthermore when CMB is more than 5 plus NLR or CRP more than 3, the prediction in primary outcomes is significant (all p < 0.05), but not in secondary outcomes.
Conclusions: Our multi-centered cohort study suggests that CMB counts > 5 were not associated with the prognosis of LAA stroke, and CMB counts > 5 with high levels of inflammation (NLR or CRP > 3) were associated with a poor prognosis of LAA stroke.
Bioinformatics Approach Based on the Cancer-Immune Cycle Identifies Potential Immunotherapeutic Targets in Diffuse Gliomas
Authors: Zhang Qinghua , Li Xinglong , Wang Run , Yu Yang , Li Mao , Xu Peizhi 
Published: November 2022

Abstract

Immunotherapy as monotherapies for diffuse gliomas fails to achieve satisfying results, while immunosuppression shows a greater challenge. Therefore, identifying immunosuppressive targets and developing novel combination treatments for immunotherapy could be promising. First, we tried to combine the cancer-immunity cycle score and diffuse glioma transcriptome data for weighted gene co-expression network analysis. We found significant gene modules and hub genes based on module membership (MMhub) statistics and protein-protein interaction networks (PPIhub). Then, we further obtained 37 common genes among MMhub and PPIhub. GO analysis revealed that these genes were significantly involved in the chemical synaptic transmission, glutamatergic synapse, and syntaxin-1 binding. The KEGG pathway analysis revealed they were enriched with the synaptic vesicle cycle, and glutamatergic synapse. Then, we identified 10 critical hub genes (SYN1, SNAP25, STXBP1, VAMP2, APBA1, DLG4, CPLX1, RIMS1, UNC13A, and GRIN1) using the Degree algorithms of cytoHubba plug-in. Finally, we further confirmed that these hub genes shape an immunosuppressive TME based on the evidence that they are negatively correlated with a majority of the immunological status of TME in diffuse gliomas. The result shows that these genes may be potentially unreported immunosuppressive targets in diffuse gliomas.
Dysregulation of SMAD4, LINC00667 and LINC00909 could be used as effective diagnostic markers in breast cancer incidence
Authors: Esfahani Soudabeh Madhkhan , babaei Ali , Tabuk Arezou , Omidghaemi Shadi , Azadeh Mansoureh 
Published: November 2022

Abstract
Breast cancer is considered a life-threatening disease among females globally which early diagnosis and treatment in the initial stages can be very effective. SMAD4 is a key regulator of TGF-β pathway that is known to play an essential role in breast cancer. Long non-coding RNAs (lncRNAs) are considered to be potential regulatory factors for several cancers that are not definite about the main role of two LncRNAs, LINC00909 and LINC00667, on breast cancer. In this study, we focus on identifying the possible correlation between expression levels of SMAD4 gene, LINC00909 and LINC00667 in breast carcinoma, as well as their potential roles in the diagnosis of breast cancer. To determine the extent of expression of these factors in 25 paired tumor-normal patient tissues, quantitative real-time PCR (polymerase chain reaction) was used. Statistical analysis showed a significant increase in the expression of the SMAD4 gene in tumor cells compared with control samples, while the expressions of LINC00909 and LINC00667 increased dramatically. As well as, specificity and sensitivity between all three criteria and breast carcinoma were statistically significant. furthermore, we observed the positive relationship between expression of LINC00909 and HER2/neu in the tumor tissues, whereas there was not another correlation between clinicopathological features and SMAD4 gene, LINC00909 and LINC00667. Moreover, we discovered a positive association between the expression of LINC00667 and LINC00909. altogether, we conclude that, SMAD4 could be considered as a potential diagnostic biomarker for breast cancer, and two lncRNAs, especially LINC00909, were identified to play an important role in the identification of breast cancer.
Modelling monthly trends in regional temperatures for the United Kingdom
Authors: Mills Terence C. 
Published: November 2022

Abstract
Since 2019 the U.K. Met Office has provided monthly observations, beginning in 1884, on maximum, minimum and mean monthly air temperatures for the U.K. and its regions. Time series analyses of these data are reported in this paper, using a deterministic monthly trends model. Although the U.K. has seen significant trend temperature increases between 1884 and 2021, these increases differ depending on whether maximum, minimum, or mean temperatures are being considered, with trend minimum temperature increases being greater than trend maximum temperature increases. There is also a difference in the trends exhibited by temperatures in the central and peripheral regions of the U.K., with rather larger trend increases being found in the former than in the latter. The largest trend increases are invariably found during the autumn months, usually October, while the smallest are found in June for maximum temperatures, which are usually insignificant, and in winter for minimum temperatures.
Biological Outcome and Stress Analysis of Angled Abutment on Implant Supported Single and Partial Denture Prostheses
Authors: Tuwaijri Sahr Al 
Published: November 2022

Aim:
To study the biological outcomes of angled abutments when used to restore single or partial fixed implant supported prosthesis.

Methodology:
An online search using Medline (Ovid) and PubMed databases was conducted using terms and combinations such as; angled abutment, bucco-lingual angulation, biological complication, marginal bone loss and implant supported fixed partial prosthesis. The focus of the study was to evaluate the effect of bucco-lingual/palatal angulation with implant supported single or partial FPD, which was conducted through specific inclusion and exclusion criteria.

Results:
The search revealed a total of 8 human in vivo and 10 in vitro studies. Of that, three in vivo studies were excluded and two from in vitro studies.

Conclusion:
According to the available studies, no significant bone loss was associated with single and partial implant supported prostheses when angled abutments are used to correct the tilted buccolingual implants. The results should be evaluated carefully due to the short follow up duration of the clinical studies; further long term follow up studies are needed. In cases where implants were misplaced, the best is to use platform switched implants with a smooth neck, maintain at least a minimum of 2 mm or more of buccal bone and utilize the lowest angulation values as possible.
Anatomy of Vital Contents of Infratemporal Fossa: their Variations, Clinical and Surgical Significance - A literature review
Authors: Somayaji Krishnaraj , Rodrigues Vincent , Kumar Naveen , Aithal P Ashwini , KG Mohandas Rao 
Published: November 2022

Background:
The infratemporal fossa is an anatomically complex and pathologically interesting region in the head and neck. Location and clinically significant vital structures in it make infratemporal fossa an area of interest to neurosurgeons specializing in skull base surgery, and maxillofacial surgeons. Although a variety of surgical approaches like endonasal, zygomatico-transmandibular, transzygomatic, transmaxillary, and facial translocation to this region have been developed, the surgical anatomy of this region is complex and remains challenging for most of the practitioners. Compilation of case reports on anatomical variations of the infratemporal fossa contents and comprehensive discussion concerning their clinical and surgical significance is lacking.

Objective:
To highlight the normal and abnormal anatomy of the contents of infratemporal fossa with emphasis on clinical importance of these structures.

Methods:
Articles from peer-reviewed journals and reputed standard textbooks were searched online using appropriate key words and only the articles which were deemed relevant were selected for further review.

Results:
Out of about 400 research articles, only 77 articles identified to be appropriate to the objectives were used in this literature review.

Conclusion:
Anatomical location and presence of functionally and clinically vital structures make the infratemporal fossa very important for dentists, otolaryngologists, neurosurgeons and maxillofacial surgeons. Knowledge of normal and variant anatomy of this area is very crucial for surgically handling the various complications like hearing loss, facial nerve weakness, temporomandibular joint dysfunction etc during various surgical procedures.
Accuracy, Precision, and Efficiency of Three-Dimensional (3D) Dental Lab Scanners: A Comparative Study of Two Systems
Authors: Alalwan Rahaf , Alessa Reuof , Alghurairi Norah , Alaqail Huda , Awawdeh Mohammed , Masuadi Emad 
Published: November 2022

Purpose:
To compare the accuracy, repeatability, reproducibility, and time efficiency between two digital lab scanners (inEos X5 Sirona and KaVo SMD ARCTICA CAD/CAM Scanners) by the traditional method using a digital caliper.

Methods:
Pair of dental casts (upper and lower) were duplicated using an elastic putty mold to make ten copies of each. Following that, a total of twenty models were scanned in each scanner (Sirona and KaVo) separately by three different calibrated operators. Each operator repeated the scan at an interval of 48 hours. Fifteen measurements for each model were obtained in three different planes (vertical, horizontal, and transfers) following the same protocol. Measurements were obtained manually using a Boley gauge and digitally by the scanner company software. The two scanners that were assessed were; Sirona and KaVo indirect lab Scanners.

Results:
The coefficient of variations was between 1%- 8%, although statistically significant in some groups, but clinically the differences were insignificant and within the accepted range. Correlations between the inter and Intra operator reliability were assessed using the Intraclass Correlation Coefficient in Tables 5-6. The reliability of the increased distance of the measurement seems more consistent. The variations of Correlations among operators increased as the distance measured decreased, even though all operators were calibrated respectively. Operators’ feedback was that KaVo was easier to learn. However, timewise Sirona seemed more efficient. The average time for the Sirona scanner was less than half a minute with average scanner time (4.3 and 3.8 minutes). Based on various parameters recorded, both scanners proved to be accurate with no clinically significant differences detected between the groups.

Conclusion:
Both scanners proved to be accurate with no clinically significant differences detected between the groups. These two scanners were reliable tools to scan and reproduce digital dental records. The inEos X5 Sirona Scanner seemed to be more efficient time-wise than the KaVo SMD ARCTICA CAD/CAM Scanners.
Assessing The Proximity of the Roots of Maxillary Molars and Premolars to the Maxillary Sinus in UAE Residents
Authors: Mohammed Alsaegh , Reem Almutairi , Rawan Alqudaifi 
Published: November 2022

Background:
The proximity of the roots of the maxillary posterior teeth (MPT) to the maxillary sinus (MS) may result in an increased risk of the development of MS pathology. Moreover, surgical procedures for the MPT, which are close to the MS can result in several complications like oroantral communication and displacement of roots into the MS.

Objective:
This cross-sectional study evaluated the MPT's proximity to the MS using digital panoramic radiography in a sample of individuals living in the United Arab Emirates (UAE).

Methods:
A total of 141 panoramic radiographs showing the presence of all MPT were retrieved from the Oral Radiology Department of Ajman University, Fujairah Campus. Thus, the proximity of 1410 MPT to the MS was evaluated on a scale of zero to three.

Results:
The roots of the first and the second molars are the closest to the MS (χ2 = 374.612; p 0.000). The distance between the roots of MPT and MS did not differ statistically between males and females (χ2 = 2.44, p= .124), nor between the right and left sides (χ2 = 0.46, p= .872). However, there was a highly significant negative correlation between the root-sinus proximity and age. (rho= -.201, p < .001).

Conclusion:
In UAE residents, the roots of the first and second molars are closer to the MS than other MPT. Therefore, more precautions should be taken when doing a surgical procedure in this region.
Safety Facets and Efficacy Strictures of Dhatryadi ghrita
Authors: Pal Rashmi Saxena , Mishra Amrita 
Published: November 2022

Background:
Latest scientific techniques like heavy metal content, microbial load estimation and pesticide residues are essential for fulfilling WHO guidelines for herbal drug formulations like Ghrita.

Methods:
In the present study, formulated Ghrita sample was selected for estimation of heavy metals as lead (Pb), cadmium (Cd), mercury (Hg), microbial load and pesticide residues.

Results:
The heavy metals, microbial load and pesticide residues study of the formulated Ghrita follow the standard parameters.

Conclusions:
This study can be helpful for the future research regarding establishment of safety profile and therapeutic efficacy of Ghrita formulations.
The Presence of the Kurdistan Region- Iraq as a Non-state Actor at the International Level
Authors: Faraj Anwar Mohamed , Najm Zana 
Published: November 2022

The last decade of the 20th century bring about some global and regional changes and developments. Perhaps the most important for us (in this part of Kurdistan) is the reemergence in international arena and creation of a self-governing authority and a de facto region called the Kurdistan Region - Iraq.
Highlighting this phenomenon and understanding its meaning and dimensions will be the main problem of our research and we assume that the Kurdistan Region-Iraq is present at the international level and can act as a non-state actor in international relations. Therefore, we use the concept of non-state actors as a theoretical tool to approach the subject and in order to determine the boundaries of our discussion and level of analysis; we resort to the three images theory or the so-called levels of analysis.
Regarding the time framework of our research, it starts from the last decade of the last century until the present time, and we have a look at the future of this presence. Therefore, we divide our research into two sections: In the first section, we discuss non-state actors as the theoretical basis of the research. The second section will be devoted to discussing the presence of the Kurdistan Region of Iraq as a non-state actor at the international arena and the opportunities and challenges of this presence, and consequently we will focus on the future of this presence.
SUAyED: la oportunidad de una nueva vida
Authors: Sánchez Ortiz Álvaro 
Published: November 2022

En forma de cuento, expongo cómo, al haber cometido un error en mi elección de carrera, sufrí problemas de ansiedad, hasta que tuve la oportunidad de estudiar lo que realmente quería, gracias al suayed. No ha sido fácil, y hay que tener muy presentes las características particulares del sistema abierto, pero ha sido una nueva oportunidad en la vida que me ha permitido corregir el rumbo. Por eso, quiero dar testimonio de mi gratitud hacia el Sistema de Universidad Abierta y Educación a Distancia.
Pandemia y visibilidad de la educación a distancia
Authors: Rodríguez Salinas Argenis 
Published: November 2022

Este texto es la reflexión de un profesor de la modalidad a distancia de la unam sobre la visibilidad de esta forma de enseñanza, a partir del confinamiento producto de la pandemia por la covid-19. Para quienes venían trabajando en educación a distancia poco fue lo que cambió, pero para el grueso de la población, la pandemia significó adaptarse a una modalidad desconocida, relegada, la cual incluso llegó a despertar cierta desconfianza. Se incluyen experiencias y proyecciones sobre el futuro de la modalidad a distancia, y se analizan áreas de oportunidad y aciertos, que invitan a repensar temas importantes como la sociedad de la información, brecha digital, educación superior a distancia, y el empuje de la modalidad híbrida en un ambiente de postpandemia.
Retos de la experiencia estudiantil en el SUAyED
Authors: Jiménez Reséndez Iris Azucena , Martínez Hernández Yadira 
Published: November 2022

En el presente testimonio se propone mostrar la experiencia de una exalumna de la Licenciatura en Pedagogía, modalidad a distancia, del Sistema de Universidad Abierta y Educación a Distancia (suayed), de la Facultad de Filosofía y Letras de la unam, desde el punto de vista del estudiante y del docente. Se retoman primero algunas de las características de estas modalidades educativas, también llamadas no presenciales. Posteriormente, se plantean algunos de los retos a los que se enfrenta el estudiantado en la carrera, relacionados en particular con el desarrollo de habilidades de escritura. Se dejan ver algunas otras dificultades que puede encontrar un estudiante del sistema a distancia, como la realización de algunos trámites escolares que requieren la asistencia personal a la facultad.
A gran necesidad, gran diligencia
Authors: Báez Pérez Leticia 
Published: November 2022

En el presente podcast se narran, brevemente, las principales necesidades que enfrentó una egresada en su proceso como estudiante del suayed psicología. Los puntos que se abordan fueron pensados con base en la experiencia personal y en la recopilación realizada gracias a la vivencia como tutora del Programa Institucional de Tutorías (pit) de algunos alumnos. Se abordan temas como la gestión del tiempo, el apoyo emocional, la autogestión del aprendizaje y la creatividad estudiantil. Esta narración busca compartir, de manera amena y cercana, no solo aquello que, en su momento, fue importante para la estudiante sino también las soluciones que generó y que pueden ser de ayuda para quienes se identifiquen con ciertas problemáticas.
Tinjauan Yuridis Sosiologis Perlindungan Identitas Anak Korban Kejahatan Seksual
Authors: Rahmawati Clarysa Dwi , Suprayitno Wasis , Kurniawan Kukuh Dwi 
Published: November 2022

Legal protection for children who are victims of sexual crimes is a manifestation of the obligations given by the State specifically. One of these protections is the protection of the confidentiality of the identity of children who are victims of sexual crimes. This embodiment aims to prevent children from negative treatment from any party that can adversely affect their growth and development of children. It has been explained in the provisions of law No. 11 of 2012 concerning the Juvenile Criminal Justice System Articlen19 paragraph (1). However, there are still many identities of children in conflict with the law that are not kept secret in case decisions are published on the Supreme Court Decision Directory Site. Therefore, the researchers raised two problem formulations. First, how to protect the identity of child victims of sexual crimes according to the laws and regulations. Second, how to protect the identity of child victims of sexual crimes according to the Malang District Court Class IA. The research method used a sociological juridical approach to collect literature study materials and interviews. Conclusions and suggestions from writing this final project, namely Article 19 of Law Numbern11 ofn2012 concerning the Criminal Justice System regarding the identity of children who are victims of sexual crimes whose identities are published if there are parties who violate the law that has set them up. Strict sanctions.