bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surgery of Motor Eloquent Glioblastoma Guided by TMS-Informed Tractography: Driving Resection Completeness Towards Prolonged Survival
Authors: Weiss Lucas Carolin , Faymonville Andrea Maria , Loução Ricardo , Schroeter Catharina , Nettekoven Charlotte , Oros-Peusquens Ana-Maria , Langen Karl Josef , Shah N. Jon , Stoffels Gabriele , Neuschmelting Volker , Blau Tobias , Neuschmelting Hannah , Hellmich Martin , Kocher Martin , Grefkes Christian , Goldbrunner Roland 
Published: May 2022

BackgroundSurgical treatment of patients with glioblastoma affecting motor eloquent brain regions remains critically discussed given the risk–benefit dilemma of prolonging survival at the cost of motor-functional damage. Tractography informed by navigated transcranial magnetic stimulation (nTMS-informed tractography, TIT) provides a rather robust estimate of the individual location of the corticospinal tract (CST), a highly vulnerable structure with poor functional reorganisation potential. We hypothesised that by a more comprehensive, individualised surgical decision-making using TIT, tumours in close relationship to the CST can be resected with at least equal probability of gross total resection (GTR) than less eloquently located tumours without causing significantly more gross motor function harm. Moreover, we explored whether the completeness of TIT-aided resection translates to longer survival.MethodsA total of 61 patients (median age 63 years, m = 34) with primary glioblastoma neighbouring or involving the CST were operated on between 2010 and 2015. TIT was performed to inform surgical planning in 35 of the patients (group T; vs. 26 control patients). To achieve largely unconfounded group comparisons for each co-primary outcome (i.e., gross-motor functional worsening, GTR, survival), (i) uni- and multivariate regression analyses were performed to identify features of optimal outcome prediction; (ii), optimal propensity score matching (PSM) was applied to balance those features pairwise across groups, followed by (iii) pairwise group comparison.ResultsPatients in group T featured a significantly higher lesion-CST overlap compared to controls (8.7 ± 10.7% vs. 3.8 ± 5.7%; p = 0.022). The frequency of gross motor worsening was higher in group T, albeit non-significant (n = 5/35 vs. n = 0/26; p = 0.108). PSM-based paired-sample comparison, controlling for the confounders of preoperative tumour volume and vicinity to the delicate vasculature of the insula, showed higher GTR rates in group T (77% vs. 69%; p = 0.025), particularly in patients with a priori intended GTR (87% vs. 78%; p = 0.003). This translates into a prolonged PFS in the same PSM subgroup (8.9 vs. 5.8 months; p = 0.03), with GTR representing the strongest predictor of PFS (p = 0.001) and OS (p = 0.0003) overall.ConclusionThe benefit of TIT-aided GTR appears to overcome the drawbacks of potentially elevated motor functional risk in motor eloquent tumour localisation, leading to prolonged survival of patients with primary glioblastoma close to the CST.
A Latent Class Analysis on Symptoms of Prolonged Grief, Post-Traumatic Stress, and Depression Following the Loss of a Loved One
Authors: Heeke Carina , Franzen Minita , Hofmann Hendrik , Knaevelsrud Christine , Lenferink Lonneke I. M. 
Published: May 2022

BackgroundThe loss of a significant other can lead to variety of responses, including prolonged grief disorder (PGD), posttraumatic stress disorder (PTSD), and depression. The aim of this study was to replicate and extend previous research that indicated that three subgroups of bereaved individuals can be distinguished based one similar post-loss symptom profiles using latent class analysis (LCA). The second aim was to examine whether sociodemographic and loss-related characteristics as well as the extent of meaning making were related to classes with more pervasive psychopathology.MethodsTelephone-based interviews with 433 Dutch and German speaking persons who had lost a significant other at last 6 months earlier were conducted. Self-rated PGD, PTSD, and depression symptoms were assessed. LCA was conducted and correlates of class-membership were examined using the 3step approach.ResultsThe LCA resulted in three distinct classes: a no symptoms class (47%), a moderate PGD, low depression/PTSD class (32%), and a high PGD, moderate depression/PTSD class (21%). A multivariate analysis indicated that female gender, a shorter time since loss, an unexpected loss and less meaning made to a loss were significantly associated with membership to the moderate PGD, low depression/PTSD and high PGD, moderate depression/PTSD class compared to membership to the no symptom class. Losing a child or spouse, a shorter time since loss, and having made less meaning to the loss further distinguished between the high PGD, moderate depression/PTSD symptom class and the moderate PGD, low depression/PTSD class.DiscussionWe found that the majority of individuals coped well in response to their loss since the no symptom class was the largest class. Post-loss symptoms could be categorized into classes marked by different intensity of symptoms, rather than qualitatively different symptom patterns. The findings indicate that perceiving the loss as more unexpected, finding less meaning in the loss, and loss-related factors, such as the recentness of a loss and the loss of a partner or child, were related to class membership more consistently than sociodemographic factors.
Decreased Connectivity in Precuneus of the Ventral Attentional Network in First-Episode, Treatment-Naïve Patients With Major Depressive Disorder: A Network Homogeneity and Independent Component Analysis
Authors: Luo Liqiong , Lei Xijun , Zhu Canmin , Wu Jun , Ren Hongwei , Zhan Jing , Qin Yongzhang 
Published: May 2022

Background and ObjectiveThe ventral attentional network (VAN) can provide quantitative information on cognitive problems in patients with major depressive disorder (MDD). Nevertheless, little is known about network homogeneity (NH) changes in the VAN of these patients. The aim of this study was to examine the NH values in the VAN by independent component analysis (ICA) and compare the NH values between MDD patients and the normal controls (NCs).MethodsAttentional network test and resting-state functional magnetic resonance imaging (rs-fMRI) data were collected from 73 patients, and 70 NCs matched by gender, age, and education years. ICA and NH were employed to evaluate the data. Moreover, the NH values were compared, and Spearman's rank correlation analysis was used to assess the correlations with the executive control reaction time (ECRT).ResultsOur results showed that the first-episode, treatment-naive MDD patients had decreased NH in the right precuneus (PCu) and abnormal ECRT compared with NCs. However, no significant correlation was found between the NH values and measured clinical variables.ConclusionOur results highlight the potential importance of VAN in the pathophysiology of cognitive problems in MDD, thus offering new directions for future research on MDD.
An Approach for the Analysis of Energy Resource Selection Based on Attributes by Using Dombi T-Norm Based Aggregation Operators
Authors: Waqar Mujab , Ullah Kifayat , Pamucar Dragan , Jovanov Goran , Vranješ Ðordje 
Published: May 2022

Dombi t-norm (DTN) and t-conorm (TCN) are among the most effective triangular norms in fuzzy systems for aggregation purposes. The environment of interval-valued intuitionistic fuzzy (IVIF) set gives us precision in expressing uncertain information by using a membership grade (MG) and non-membership grade (NMG) in the form of closed subintervals of 0, 1. The goal of this paper is to introduce DTN-based aggregation operators (AOs) for IVIF numbers (IVIFNs) and study their performance in the evaluation of the worth of energy recourses to be opted in Pakistan to deal with the energy crises situation. We first introduced some DTN and TCN-based operations for IVIFNs and developed two new AOs known as IVIF Dombi weighted averaging (IVIFDWA) and IVIF Dombi weighted geometric (IVIFDWG) operators. The validity and fitness of the proposed operators are tested. A case study is presented where the energy resources of Pakistan are discussed and the problem of the selection of sustainable energy resources in the context of Pakistan is investigated. The sensitivity analysis of the proposed IVIFDWA and IVIFDWG operators is studied and a comparative analysis of the current work with previous studies is established.
The Strategies of Internalizing the Negative Externalities in the Company’s Sustainable Development
Authors: Kozlov Dmytro 
Published: May 2022

The study focuses on externalities which play the important role in sustainable development. They indicate the impact of the company’s activity on the third persons. On the basis of findings, the externalities from the company’s financial reports are monetarized. The externalities exerting influence on the profit or loss as well as on the total balance of the company are analysed. Positive and negative externalities are identified in order to internalize the negative externalities with the help of definite strategies of sustainable development. It is emphasized that the long-term action plans to ensure competitiveness, environmental protection and social legitimacy help to adapt to expected market, environmental and social developments. The study discusses current strategies: defensive (reactive), offensive that are viewed from the economic, environmental and social perspective. It is investigated that the defensive strategies are limited to the implementation of relevant laws or agreements in order to avoid negative consequences for the legislator. On the other hand, offensive, inward-looking strategies are aimed at aligning the company’s structures (organizations) and systems (environmental management systems) with the requirements of sustainable development, motivation and qualification of employees for sustainable development. The environmental sustainable development strategies are focused on a variety of ecological aspects. The emergence of economic, environmental and social risks and opportunities in machine-building company with their potential solutions is underlined. As the matter of fact, using the right strategy, the company can easily go through the internalization of negative externality to exert more substantial impact on the society, environment and the economy.
Percepção dos usuários sobre Acolhimento e Classificação de Risco nas UPAS: revisão integrativa
Authors: De Mello Correa João Victor , Rodrigues Teixeira de Castro Renata , Mafra Moreno Adalgiza , Walquíria de Carvalho Rúbia , Coelho de Almeida Lima Raphael , Rodrigues Teixeira de Castro Roberta 
Published: May 2022

Objetivos. Analisar a produção científica existente sobre a percepção dos usuários quanto aos aspectos positivos e negativos relacionados ao Acolhimento e Classificação de Risco (ACCR) realizado nas UPA, com vistas a subsidiar a reflexão e o aprimoramento do serviço prestado. Método. Trata-se de uma revisão integrativa de literatura, realizada nas bases de dados PUBMED, BVS e Google acadêmico, utilizando descritores específicos para cada base. Foram incluídos artigos completos, publicados entre 2010 e 2021 e disponíveis nos idiomas português, espanhol e inglês, sendo excluídos os artigos de revisões, teses, dissertações, artigos duplicados e os estudos que não contemplavam o tema em questão. Após a aplicação dos critérios de elegibilidade, foram selecionados 7 artigos. Resultados. Os aspectos positivos identificados traduzem o esforço realizados pelos profissionais, mesmo em condições inapropriadas, de exercerem suas práticas de forma humanizada e acolhedora. Por outro lado, os problemas identificados caracterizam uma rede de atenção fragmentada e pouco resolutiva, que não tem conseguido atuar de forma preventiva, nem atender as demandas da população em tempo hábil. Diferentes recomendações práticas foram propostas, porém o grande desafio é sua operacionalização em um cenário de restrições. Conclusão. Revela-se a necessidade de reflexões para além dos muros das UPAS, através de uma análise crítica por parte dos gestores, sobre a necessidade de intervir a nível de Rede de Atenção à Saúde, tendo em vista que todos os elementos que a compõem precisam estar funcionando adequadamente e de forma articulada para que nenhum deles se sobrecarregue.
Efeitos da fisioterapia aquática em indivíduos com distrofia muscular de Duchenne: revisão integrativa
Authors: Mendes Fernanda Racolto , Silva Letícia Louzano , Martins Kaitiana , Fiumi Adriana , Castro Caio Roberto Aparecido de Paschoal , Braga Douglas Martins 
Published: May 2022

Introdução. A Distrofia Muscular de Duchenne (DMD) é uma doença de origem genética, ligada ao cromossomo X, de caráter recessivo, caracterizada pela ausência da proteína distrofina. Com a progressão da doença esses indivíduos são impossibilitados de realizar determinadas atividades em solo. A fisioterapia aquática por meio das propriedades físicas da água pode facilitar movimentos e possibilitar vivências posturais comprometidas pela doença. Objetivo. Verificar os efeitos da fisioterapia aquática em indivíduos com DMD por meio de uma revisão integrativa. Método. Este estudo é uma revisão integrativa, desenvolvido com base na estratégia PICO. Foram incluídos estudos transversais, séries de caso, caso controle, controlado randomizado, ensaio clínico randomizado controlado. As buscas foram realizadas nas plataformas Pubmed, Pedro, Biblioteca Virtual em Saúde (Lilacs), CINAHL, Cochrane, Embase e Scopus. Foram encontrados 740 registros, desses 18 artigos foram selecionados e classificados por níveis de evidência científica da Agency for Healthcare Research and Quality (AHRQ). Resultado. Dos estudos identificados nesta revisão, segundo as categorias do AHRQ, a maioria é classificado como nível de evidência IV (série de caso e caso controle), o que resulta em nível de evidência mediano. A maioria dos estudos investigou mobilidade funcional, capacidade respiratória e função motora. Conclusão. Esta revisão integrativa concluiu a fisioterapia aquática promove efeitos positivos para indivíduos com DMD. São necessários ensaios clínicos aleatorizados controlados abordando a fisioterapia aquática nos diferentes estágios da doença e nos diversos desfechos desta população.
Analisis Variasi Diameter Pulley pada Mesin Hidrolik Pencetak Batu Bata terhadap Sifat Mekanik menggunakan Metode Taguchi
Authors: Rahmadianto Febi , Kurniawan Arif , Pohan Gerald Adityo , Febritasari Rosadila , Pratama Nurida Sixta 
Published: May 2022

Batu bata merupakan salah satu material yang digunakan dalam konstruksi. Pemanfaatan teknologi dalam pengolahan batu bata sangat diperlukan untuk meningkatkan produktivitas batu bata di tengah pesatnya peningkatan pembangunan di Indonesia. Efektivitas sistem teknologi akan mengalami penurunan seiring berjalannya waktu yang disebabkan oleh pulley yang bekerja pada mesin tersebut. Sehingga pemilihan diameter pulley merupakan kunci utama untuk menghasilkan batu bata yang optimal ditinjau dari putaran pompa, tekanan fluida dan kekuatan impact dari hasil pencetakan batu bata tersebut.
Penelitian ini bertujuan untuk menganalisis sifat mekanik mesin hidrolik terhadap beberapa variasi diameter pulley yang digunakan pada mesin pencetak batu bata. Analisis variasi diameter pulley ini dilakukan untuk mendapatkan kerja mesin yang tetap baik dan tidak melebihi jangkauan sistem kerja standartnya dan menghasilkan cetakan batu bata yang optimal.
Hasil penelitian menunjukkan bahwa nilai putaran pompa terhadap variasi diameter pulley pompa 3, 5dan 7 inci masing-masing adalah 1400 rpm, 840 rpm dan 600 rpm, sedangkan nilai tekanan fulida yang diperoleh pada masing-masing variasi diameter pulley pompa adalah 300 psi, 150 psi dan 100 psi. Untuk nilai rata-rata kekuatan impact, masing-masing diperoleh sebesar 0,05297 J/mm2, 0,04809 J/mm2 dan 0,04715 J/mm2 dan hasil penelitian ini juga membuktikan bahwa hasil analisis Metode Taguchi menggunakan karakteristik kualitas yaitu Larger the better yang artinya pencapaian karakteristik kualitas semakin besar semakin baik.
Dari hasil penelitian dapat disimpulkan bahwa kondisi optimal hasil pencetakan batu dengan mesin hidrolik pencetak batu bata diperoleh pada puley pompa diameter 3 inci dengan waktu penekanan 10 detik, dan diameter pulley motor 3 inci dengan nilai putaran pompa mesin hidroliknya adalah 1400 rpm, tekanan fluida 300 psi dan rata-rata kekuatan impact sebesar 0,05297 J/mm2.
PERENCANAAN STRATEGIS SISTEM INFORMASI PADA PERUSAHAAN SLINGBAG SALATIGA MENGGUNAKAN METODOLOGI WARD AND PEPPARD
Authors: Rional Aprinda Vido , Fritz Wijaya Agustinus 
Published: May 2022

Slingbag Salatiga merupakan perusahaan/produsen mikro kecil menengah yang bergerak pada bidang penjualan barang-barang fashion wanita terutama tas atau pakaian. Dalam menjalankan aktivitas proses bisnisnya, perusahaan Slingbag Salatiga masih menggunakan cara manual atau tradisional di beberapa bidangnya, salah satu contohnya merupakan aktivitas pencatatan keuangan perushaan. Sehingga diperlukan perencanaan strategis SI/TI yang tepat dan sesuai dengan kebutuhan perusahaan saat ini. Semakin baik perencanaan strategis yang dibuat maka aktivitas proses bisnis yang ada dalam perusahaan juga berjalan dengan lebih efektif dan efisien. Penelitian ini menggunakan metode pengumpulan data secara wawancara dengan pemilik perusahaan dan observasi langsung ke perusahaan Slingbag Salatiga. Metode yang digunakan dalam merancang perencanaan strategis pada penelitian ini menggunakan metode Ward and Peppard. Dimana meliputi analisis internal dan eksternal perusahaan menggunalan analisis Value Chain, analisis SWOT, dan analisis Porter Five Forces. Output yang dihasilkan merupakan rekomendasi sistem informasi yang dipetakan menggunakan McFarlan Strategic Grid dan dapat diimplemntasikan oleh perusahaan dalam tiga tahun ke depan.
Perancangan Sistem Smart Church Berbasis Internet Of Things(IoT)
Authors: Joas Kirene Wardaini , Wibowo Suryo Adi , Pranoto Yosep Agus 
Published: May 2022

Pada masa pandemi terpaksa jemaat harus beribadah dari rumah karena pemerintah Indonesia menerapkan kebijakan protokol Kesehatan oleh karena itu tata cara ibadah cenderung bebasis online. Demi mencegah menularnya virus covid salah satunya adalah periksaan suhu tubuh serta menjaga jarak.
Berdasarkan hasil pengujian pada sensor suhu mlx90614 dengan nilai rata-rata diperoleh dari jumlah eror di bagi banyaknya data , kemudian hasil dari 10 kali percobaan untuk sensor suhu tersebut cukup akurat dengan rata – rata tingkat error sebesar 3,6%. Pengujian pada alat pada kursi , yang dimana ESP akan menerima koneksi dari server berupa status booking dan di tampilkan ke LCD serta warna lampu LED sesuai dengan status yang diterima.
Berdasarakan hasil pengujian RFID yang mendeteksi UID dari kartu member jemaat dan menampilkan UID tersebut ke lcd, lalu data di kirim ke server untuk dicek status pembookingan. lalu server mengirim respon ke Arduino dan respon di tampilkan di lcd . Pada menu reservation sudah tersedia link google meet.
IMPLEMENTASI METODE GEOFENCY PADA SISTEM KEAMANAN KENDARAAN
Authors: Maureta Sonia , Orisa Mira , Agus Pranoto Yosep 
Published: May 2022

Dengan berkembangnya jaman yang sangat cepat, kebutuhan setiap individu juga meningkat namun terjadinya pandemi covid-19 menyebabkan banyaknya manusia yang tidak mampu memenuhi kebutuhannya atau yang disebut dengan krisis ekonomi. Turunnya aktivitas perekonomian dan terbatasnya mobilitas barang dan jasa, serta pembatasan ruang gerak penduduk, pada akhirnya memukul pendapatan perusahaan dan masyarakat. Akibatnya, pemutusan hubungan kerja dan merumahkan karyawan terjadi dimana – mana. Kondisi tersebut yang menyebabkan tindak kriminal semakin meningkat seperti pencurian pada kendaraan termasuk mobil rental. Dalam Pembuatan aplikasi ini, menggunakan menggunakan metode geofency dengan perhitungan Euclidean Distance yang digunakan untuk menghitung radius dari titik pusat. Sistem keamanan kendaraan ini menggunakan mobile android yang akan digunakan sebagai controlling menjadi receiver satellite GPS dan akan mengirimkan latitude serta longitude pada database, selain itu output seperti Sirine dan lcd akan dijalankan melalui sistem mobile android. Fungsi ini nantinya akan menjadi acuan apakah mobil masih berada di radius aman atau tidak untuk mengantisipasi adanya penggelapan mobil. Berdasarkan hasil analisa dan pengujian perancangan sitem keamanan kendaraan, diketahui bahwa sistem menggunakan modul GSM dan modul GPS memerlukan waktu pengujian dengan rentan waktu rata-rata 30 hingga 60 detik dan mengupload data dengan rata-rata 30 detik. Metode geofency dengan bantuan Euclidean Distance menghasilkan selisih jarak rata-rata 0,018 km.
Kolegiata w Myszyńcu w świetle nowych ustaleń i atrybucji
Authors: Grygiel Tomasz 
Published: May 2022

Największa świątynia regionu kurpiowskiego, kolegiata pw. Świętej Trójcy w Myszyńcu, początkowo uchodziła za dzieło Adolfa Schimmelpfenniga. Ostatecznie na podstawie źródeł archiwalnych ustalono, że jej projektantem był Franciszek Przecławski i, że powstała w latach 1909–1922. Zastanawiając się nad powodem pojawienia się nazwiska Schimmelpfenniga w kontekście myszynieckiej kolegiaty, autor poddaje analizie formy jej wolnostojącej dzwonnicy, tak zwanej wieży bramnej i dochodzi do wniosku, że to ten architekt odpowiadał za przebudowę dzwonnicy w latach 1867-1868.
Hubungan Kecanduan Game Online terhadap Kemampuan Berpikir Kreatif Matematis dan Self-Regulation Mahasiswa
Authors: Haswati Desty , Fitriani Rizka , Fatonah Yana Rika , Rohmah Arintika Mivtakhu 
Published: May 2022

Penelitian ini dilatarbelakangi oleh kondisi banyak mahasiswa yang memiliki hobi bermain game online yang berdampak pada hasil belajar mereka. Penelitian ini bertujuan untuk mengetahui: (1) hubungan kecanduan game online dan kemampuan berpikir kreatif matematis dan (2) hubungan kecanduan game online dan self-regulation mahasiswa. Jenis penelitian yang digunakan adalah penelitian survey dengan pendekatan korelasional menggunakan subjek penelitian pemain game online dari mahasiswa Universitas Muhammadiyah Tangerang yang diberi angket kecanduan game online dan didapatkan 14 orang untuk diberikan form lanjutan berupa soal berpikir kreatif matematis dan angket self-regulation. Berdasarkan hasil uji korelasi Spearman menunjukan: (1) nilai signifikansi kecanduan game online dan kemampuan berpikir kreatif matematis = 0.071 (a > 0.05) maka tidak ada hubungan antara kecanduan game online dan kemampuan berpikir kreatif matematis; (2) nilai signifikansi kecanduan game online dan self-regulation = 0.003 (a < 0.05) dan koefisien korelasi = -0.728, maka terdapat hubungan yang signifikan antara kecanduan game online dengan self-regulation mahasiswa dan koefisien korelasinya bernilai negatif artinya hubungan yang berbanding terbalik yakni semakin tinggi tingkat kecanduan game online maka semakin rendah self-regulation tersebut.