bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improved Sketch-to-Photo Generation Using Filter Aided Generative Adversarial Network
Authors: Raghatwan Jyoti S. , Arora Sandhya 
Published: October 2022

Generating a photographic face image from given input sketch is most challenging task in computer vision. Mainly the sketches drawn by sketch artist used in human identification. Sketch to photo synthesis is very important applications in law enforcement as well as character design, educational training. In recent years Generative Adversarial Network (GAN) shows excellent performance on sketch to photo synthesis problem. Quality of hand drawn sketches affects the quality generated photo. It might be possible that while handling the hand drawn sketches, accidently by touching the user hand on pencil sketch or similar activities causes noise in given sketch. Likewise different styles like shading, darkness of pencil used by sketch artist may cause unnecessary noise in sketches. In recent year many sketches to photo synthesis methods are proposed, but they are mainly focused on network architecture to get better performance. In this paper we proposed Filter-aided GAN framework to remove such noise while synthesizing photo images from hand drawn sketches. Here we implement and compare different filtering methods with GAN. Quantitative and qualitative result shows that proposed Filter-aided GAN generate the photo images which are visually pleasant and closer to ground truth image.
The Role of Implementation of IDSR Strategy on Indicators of the Core and Supportive Surveillance Functions at the Head of Localities
Authors: Himat S.M. H , Hasab A .AE , Elhafeez S.S Abd , Abukaraig E.A.B , Abdalmajed M.A , Abdalkarim B.A. 
Published: October 2022

Background: Disease surveillance is a cornerstone of outbreak detection and control. The evaluation of a disease surveillance system is important to ensure its performance over time.
Objectives: The role of implementation; of IDSR strategy on indicators of the core and supportive surveillance functions at the head of localities.
Materials and methods: An intervention approach (one group pre-test post-test design) was conducted and baseline data of communicable diseases surveillance was obtained from selected Kassala state, four localities, and 60 health facilities. After implementing an integrated disease surveillance and response (IDSR) strategy for six months to evaluate core and support functions. The same questionnaire (WHO- guided modified and tested questionnaire) that was used in the baseline was applied.
Results: The study showed that indicators of the supportive at the head of locality was improved at the head of four localities in terms of standards and guidelines, training, supervision and resources which witnessed significant improvement during pre and post intervention more than 90%.
Conclusion: Improvements in indicators of core and support functions at the locality and state levels are inextricably linked to the quality of activities carried out at health facility levels. This was noticed when the value of intervention-supported functions increased, which may also be justified by the technique of computation technique, which is based on the aggregate of indicators of health facilities.
Nivel de conocimiento y actitud de Pediatras sobre las caries de la primera infancia y salud bucal en niños de la Ciudad de Quito, 2021-2022
Authors: Andrade Janina 
Published: October 2022

La prevalencia de Caries de la infacia temprana ha aumentado rápidamente de forma global, sin embargo, la mayor prevalencia se advierte en los países en vías de desarrollo, influyendo de forma significativa en las personas, las familias y las sociedades de tal forma que se relaciona con la salud general, la calidad de vida y, guarda relación con otras enfermedades frecuentes de la infancia, debido principalmente a factores de riesgo en común con otras enfermedades no trasmisibles, por ejemplo, una elevada ingesta de azúcar, y las enfermedades relativas a otros trastornos de salud tales como la obesidad. (Organización Mundial de la Salud , 2021). El nivel de conocimiento y la actitud de los médicos pediatras frente a esta problemática es esencial para una correcta prevención como primeros proveedores de información sobre la salud de los infantes.
Por ello este estudio tiene como objetivo evaluar el nivel de conocimiento y actitud de pediatras sobre las caries de la primera infancia y salud bucal de los niños en la ciudad de Quito. En la medida en que no existe una lista de cada uno de los médicos pediatras de la ciudad de Quito, se seleccionaron a través de muestreo no probabilístico por conveniencia. Los resultados sugieren que, alrededor del 58,5% de los pediatras reconocieron la importancia de la odontología pediátrica. Alrededor del 72.7% de los pediatras realizan exámenes orales regularmente. Alrededor del 17% de los pediatras tienen conocimiento de la ECC. Solo el 32,3% de los pediatras reconoció la cariogenicidad de los jarabes medicados.
Extraction and Characterization of Fe2O3 from Red Mud PT. Indonesia Chemical Alumina West Kalimantan
Authors: Wahyinto Indi Rizki , Aritonang Anthoni B. , Zaharah Titin Anita 
Published: October 2022

Red Mud is a term used for residues or waste materials from bauxite refining. One of the main compositions of red mud is Fe2O3. This study aims to obtain the optimum extraction of Fe2O3 conditions or hematite by using APDC ligands and knowing the characteristics of Fe2O3 generated. In this study, Fe2O3 extraction begins to determine the optimum pH and ligand concentration. The results of determining the optimum conditions showed pH 1 and ligand concentration of 0.5 M. Fe2O3 characteristics can be resolve through the characterization of Fourier Transformed Infra Red (FTIR), X-ray Diffraction (XRD) and X-ray Fluorescence (XRF). The results of FTIR characterization showed the stretching vibration of Fe-O Fe2O3 phase (570.50 cm-1 and 470.20 cm-1), XRD diffractogram showed the resulting crystal shape is rhombohedralsize is 27,08 nm, while the XRF characterization results showed the mass percent Fe2O3 before extraction is 42.48% and the mass percent Fe2O3 after extraction is 72.443%.
Bacterial Profile and Antibiotic Resistance Pattern among Children with Urinary Tract Infections in Dr. Soetomo Hospital, Surabaya, Indonesia
Authors: Adhima Fauziah , Wahyunitisari Manik Retno , Prasetyo Risky Vitria , Setiabudi Rebekah Juniati 
Published: October 2022

Urinary tract infections (UTIs) are the most common infections in pediatric patients characterized by the growth of bacteria in the urine in significant numbers. Antibiotics remain the primary treatment of UTI in children. However, there has been an increase in antibiotic resistance to uropathogens worldwide due to their inappropriate and extensive uses. There is considerable geographical variation in the distribution of bacteria and antibiotic resistance pattern. Thus, to prevent further resistance and provide empirical antibiotic options, this study aims to determine the profile of bacteria and antibiotics resistance pattern among UTI pediatric patients in Dr. Soetomo Hospital. This study was performed by collecting data from the urine culture logbook at the Clinical Microbiology Laboratory of Dr. Soetomo Hospital in July-October 2019. The sample was UTI patients aged one day – 18 years due to bacterial infection with a colony count of ≥100,000 CFU/ml. In this study, 131 patients showed significant bacterial growth dominated by males and ages one month – 2 years. UTI were caused by gram-negative bacteria (74%) and gram-positive bacteria (26%), with the most bacteria found in each group were Escherichia coli and Enterococcus faecalis. E. coli showed ≥70% resistance to ampicillin, cefazoline, piperacillin, tetracycline, and trimethoprim-sulfamethoxazole. Comorbidities were dominated by hydronephrosis (10.98%), chronic kidney disease (9.79%) and hydrocephalus (8.09%). In conclusion, gram-negative bacteria were the leading cause of UTI in children with E. coli as the most common uropathogen, highly resistant to ampicillin and cefazolin. Gram-positive bacteria were less frequent with varied resistance patterns. Most common comorbidity was hydronephrosis.
The Activities on Prevention of Malaria and Filariasis Vector Bites among Indonesian Society: A Nationwide Disease Prevention Survey
Authors: Widawati Mutiara , Ipa Mara , Astuti Endang Puji , Wahono Tri , Yuliasih Yuneu 
Published: October 2022

Vector Borne Diseases are diseases that cause many problems. These diseases are spread by mosquitoes as the vectors. They transmit parasites to humans through their bites. The people who live in Indonesia have several characteristics that make them vulnerable to these diseases. Therefore, it is necessary to explore these characteristics in order to gain better prevention promotional targeting strategy. This study aims to determine the factors that can influence mosquito bite prevention behaviour in Indonesian society. The data from a nationwide survey research were used with a cross sectional design conducted once in every five years. The Riskesdas was conducted from April to May 2018 in all districts in Indonesia. The influencing factors observed were including experience of exposure to vector borne diseases (malaria or filariasis), gender, age group, education level and area of residence. This study conducted a multivariate test using logistic regression analysis to determine the factors that influence mosquito bite prevention behaviour. The results demonstrated that the factors of experience of exposure to vector borne diseases, gender, age group, education level and area of residence could determine the mosquitoes bite prevention behaviour in Indonesian society. Respondents who have experience of being exposed to malaria or filaria, under 60 years old, women, college graduates, and rural communities are more likely to prevent mosquito bites, therefore they could be empowered in promoting public awareness towards mosquito bites prevention.
DESIGN OF WHEEZING SOUND DETECTION WEARABLE DEVICE BASED ON INTERNET OF THINGS
Authors: Yanti Budi 
Published: October 2022

<p><strong>Introduction: </strong>Wheezing is one of the most common manifestations of airway obstruction. The use of a stethoscope in the wheezing examination has several disadvantages such as subjective results and depends on the auditor's hearing sensitivity. So an easy device is needed that helps determine the wheezing sound precisely. This study assembled a single tool to detect wheezing sounds based on the internet of things.<strong></strong></p><p><strong>Method</strong><strong>: </strong>This tool is designed with a microprocessor hardware connected to an electric stethoscope so that it can be attached to the patient's chest wall. Collection of chest breathing voice data accessed on kaggle.com. The creation of algorithms with Convolutional Neural Networks (CNN) was later changed to Mel Frequency Cepstral Coefficients (MFCC). This model will be implanted in a microprocessor and use python language to be able to record the sound of chest wall vibrations. The recorded sound is converted into MFCC to make it easier to perform wheezing sound detection. MFCC image results and detection results are sent to the database via the firebase database feature which stores MFCC photos in real-time as they are detected. Designing android application software using Flutter builds communication between android applications and firebase databases that allows applications to retrieve MFCC images as the final result. <strong></strong></p><p><strong>Result</strong><strong>: </strong>The results of the tool trial on five volunteers, three exacerbation asthma patients and two healthy people showed the device can detect wheezing sounds at a frequency of 400Hz with 80% accuracy through CNN and MFCC algorithms Internet of things based.<strong></strong></p><p><strong>Conclusion</strong><strong>: </strong>This tool can help health workers to accurately determine wheezing sounds, enforce the diagnosis faster, the prognosis of the disease to be better, so as to reduce the number morbidity and mortality of diseases with airway abnormalities in Indonesia<strong></strong></p><div> </div>
PENGARUH JOB STRESS DAN BURNOUT SYNDROME TERHADAP TURNOVER INTENTION PADA KARYAWAN WANITA DI KOTA MALANG
Authors: Uki Yonda Asepta  , Dhevira Pramitasari  
Published: October 2022

ABSTRAK
Sumber daya manusia adalah salah satu bagian terpenting bagi perusahaan, karena tujuan perusahaan akan tercapai apabila dapat mengelola sumber daya manusia dengan baik. Perusahaan harus menjaga hubungan yang baik antar karyawan agar tercipta lingkungan kerja yang saling memotivasi. Hal ini memberikan manfaat bagi karyawan untuk mengelola job stress dan burnout syndrome dengan baik. Apabila karyawan tidak bisa mengelola stres kerja dan burnout dengan baik, maka perusahaan akan mengalami peningkatan angka turnover intention karyawan yang berdampak pada penurunan produktivitas perusahaan. Penelitian ini menggunakan objek karyawan wanita karena karyawan wanita lebih memiliki potensi mengalami stres dan burnout lebih tinggi apabila dibandingkan dengan pekerja pria. Metode yang digunakan yaitu deskriptif survey dengan pendekatan causal comparative research, yang digunakan untuk menganalisis pengaruh variabel bebas terhadap variabel terikat. Populasi pada penelitian ini menggunakan jumlah karyawan wanita di Kota Malang dengan jumlah 184.853 orang dengan sampel sebanyak 100 orang. Hasil penelitian mengatakan bahwa job stress dan burnout syndrome berpengaruh secara parisal dan simultan terhadap turnover intention.
Kata Kunci: Job Stress, Burnout Syndrome, Turnover Intention, Karyawan Wanita
PERAN GENDER SEBAGAI MODERASI ANTARA PENGARUH KNOWLEDGE SHARING TERHADAP KINERJA KARYAWAN PT. XYZ
Authors: Siti Mahmudah  , Yulianita Rahayu  , Juju Zuhriatusobah  
Published: October 2022

Penelitian ini bertujuan untuk mengetahui sejauh mana knowledge sharing mempengaruhi kinerja karyawan dan bagaimana gender dapat memoderasi hubungan antara knowledge sharing dan kinerja karyawan. Penelitian ini menggunakan metode pengumpulan data kuantitatif dengan pengumpulan data lapangan menggunakan metode kuesioner yang dibagikan langsung kepada karyawan bagian pemasaran PT. XYZ. Analisis data menggunakan pendekatan Partial Least Square (PLS). Hasil penelitian menunjukan bahwa knowledge sharing berpengaruh positif dan signifikan terhadap kinerja karyawan dan gender belum teruji mampu berperan sebagai variabel moderasi antara pengaruh knowledge sharing terhadap kinerja karyawan.
Serial MRI manifestations and effect of immunotherapy in patients with Glutamic Acid Decarboxylase 65 (GAD65) Antibodies Related Neurologic syndromes
Authors: Zhou Lixia , Lyu Feiyan , Zhang Wenlin , Wang Liang , Qu Zhenzhen , Si Peipei , Mao Zhuofeng , Chen Ruomeng , Jia Lijing 
Published: October 2022

Abstract
Background
The autoimmune conditions involving GAD have been investigated for their association with several neurological disorders such as autism, Parkinson’s disease, schizophrenia, bipolar disorder, neuropathic pain, and epilepsy. The primary function of GAD65 is catalyzing glutamate to gamma amino butyric acid (GABA), which is further required for neurotransmission. Thus, targeting GAD65 and anti-GAD65 antibodies is of crucial importance for the improvement of the neuro-pathophysiology of various diseases.
Methods
The current work describes outcomes of initial MRI manifestations and immunotherapy in 15 Chinese patients developing anti-GAD65 autoimmune neurological syndromes. These patients received immunotherapy, a routine follow-up, and underwent serial MRI examinations (8 out of 15 patients).
Results
The findings from the MRI examination demonstrated dynamic changes in imaging with the progression of anti-GAD65 associated disease, which can be further classified into cortical/subcortical parenchymal type and mesial temporal lobe (MTL) type. Additionally, early initiation of immunotherapy showed significant improvement in symptoms, imaging findings, and prognosis, especially in patients with cortical/subcortical MRI changes.
Conclusion
The disease prognosis can be significantly improved over conventional strategies with the help of combining early immunotherapy and dynamic MRI monitoring.
Ablation of Lsd1 induces viral mimicry in thymocytes and promotes the development of innate-memory T cells
Authors: Xia Miaoran , Wang Bingbing , Sun Wujianan , Ji Dengyu , Huang Xuefeng , Yu Minghang , Su Ziyang , Chen Ping , Qu Kun , Wang Xi 
Published: October 2022

Abstract
Histone demethylase Lsd1 has been shown to play a critical role in hematopoietic differentiation. However, its physiological functions in thymocyte development remain elusive. We observed that the specific deletion of Lsd1 in thymocytes at the double-negative stage causes significant thymic atrophy and reduces peripheral T cells with impaired proliferation capacity. Single-cell RNA-sequencing (scRNA-seq) combined with strand-specific total RNA-seq and ChIP-seq analysis revealed that ablation of Lsd1 in T cell precursors led to the aberrant de-repression of endogenous retroelements (EREs), which then resulted in a viral mimicry state and activated the interferon pathway. Furthermore, deletion of Lsd1 blocked the programmed sequential down-regulation of CD8 expression at the DP→CD4+CD8lo stage and induced an innate-memory phenotype in both thymic and peripheral T cells. Overall, our study provides new insight into the function of Lsd1 as an important maintainer of ERE homeostasis in early T cell development.
Clinical outcomes and quality of life after Total Knee Replacement (TKR) - A systematic review
Authors: Dutta Ambarish , Qadeer Amatullah Sana , Rachel Jennifer , Gandhi Naline , Patra Abhilash , Nanda Lipika , Rout Sarit Kumar , John JebaMalar , Anilkumar Aiswarya , Dhopte Pratik Ramesh 
Published: October 2022

Abstract

Background

The current review aimed to refresh the existing evidence on clinical effectiveness of Total Knee Replacement (TKR) in various settings, using a wide follow-up window, and to examine the determinants influencing the success of TKR, so the evidence can be systematically synthesized.

Methodology

Studies only with pre-post study designs, measuring patient reported outcome measures (PROMs) at two time points, pre-TKR and post-TKR, were included. Commonly used PROMs, such as Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Short Form (SF-36) were harmonized across studies from worst to best and in the range of 0-100 scale. Effect Sizes (ES) were computed using pre-post mean differences in PROMs, quantifying post-TKR changes in the OA-affected knee.

Results

A total of 27 studies were included in this review. During short-term follow-up (≤ 6 months), greater improvement in WOMAC components such as pain (ES = 2.0) and function (ES = 2.3) was observed as opposed to stiffness. There was an improvement in all the scales of SF-36 except general health post-TKR. Gender (female), co-morbidities and post-operative complications were associated with poor outcomes of TKR.

Discussion

Improvement in clinical outcomes and performance was observed after TKR, especially between 6 months and 1 year. There was less improvement in PROMs in the long term but without any deterioration within 10 years of follow-up period.

Conclusion

The overall findings of this review conclude the confirmation of older knowledge with fresh evidence that TKR is definitely a clinically effective and beneficial treatment for individuals with OA knee and that too in different settings.

Systematic review registration

The systematic review protocol was registered in INPLASY (Registration No: INPLASY202240166)
Mitigation policy trust on fossil energy consumption in G7 countries: insight from avoidable policy thresholds
Authors: Abdulqadir Idris 
Published: October 2022

Abstract
This study investigated the nexuses between fossil energy consumption, economic growth, trade openness, and environmental degradation in G7 countries over the period 1965–2021. The empirical strategy for the study includes dynamic panel threshold regression (TR) analysis and quantile regression (QR) analysis. For clarity, TR is used to uncover the actionable and complementary policy thresholds in the nexuses between fossil energy consumption, trade openness, green growth, and environmental degradation. QR is utilized to explore the conditional distribution between growth outcome variables. The empirical evidence based is on TR and QR. First, using threshold regression the study revealed an actionable threshold for carbon dioxide emissions (CO2) not beyond 6.75 mts, along with a complementary threshold of 3.05bcm pd natural gas consumption, and another complementary policy threshold of 5.60% of the share of trade to GDP, respectively. The policy relevance of the thresholds is apparent to policymakers in the cartel and for policy formulation. The policy implication of this study is straightforward. The novelty of this study stalk in the extant literature on providing policymakers an actionable threshold for CO2 emissions with the corresponding complementary threshold for natural gas consumption and trade policies in the nexuses between green growth and the environment.
Environmental Pollution in Belgium and Implications for Aquatic Health
Authors: Okon Ekemini , Okocha Reuben , Yakubu Suleiman , Kipchumba Adams 
Published: October 2022

Abstract
Pollution is one of the primary contributors to the decline of biodiversity, and one of the most significant challenges facing the aquatic environment. Aquatic pollution comes from introducing a wide variety of substances negatively impacting the water bodies. Although Belgium's aquaculture and fisheries industry are underdeveloped and production is relatively low, pollutants from the environment and industry can affect the aquatic ecosystems and the behaviour of aquatic species. Therefore, research into the freshwater and marine environment is an essential component of assessing the levels of environmental pollution and proffering sustainable management and restoration practices. This study aims to present an in-depth assessment of aquatic pollution and its impacts on aquaculture and fisheries species. This review identified various studies on aquatic pollution in Belgium and discussed their implications on aquatic health. It covered surface water, groundwater, nutrient, oil, debris, microplastic, and sediment pollution across various sampling locations. This study identified a need to establish a framework for river basins in Belgium to allow for more accurate predictions regarding where land changes pose a considerable threat to aquatic populations. Furthermore, studies on microplastic pollution in the future should incorporate freshwater, estuarine, and terrestrial settings. Findings from such studies will allow for a better understanding of the whole scope of microplastic pollution.