bluuebunny/crossref_metadata_2025_split huggingface dataset:
AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL TALI PUTRI (Cassytha filiformis L.) TERHADAP Staphylococcus aureus DAN Propianibacterium acnes
Authors: Rahmawati Suci , O. Oktoviani  , Putri Rizky Lailatur Rahmah  , Heru Dwi Nugroho  , Sipriyadi  
Published: October 2022

Staphylococcus aureus dan Propianibacterium acnes adalah bakteri yang menjadi salah satu penyebab masalah jerawat pada kulit. Penelitian ini bertujuan untuk menentukan daya hambat dari ekstrak etanol 96% tali putri (Cassytha filiformis L.) terhadap S.aureus dan P. acnes. Uji aktivitas antibakteri yang dilakukan pada peneltian ini menggunakan metode difusi cakram. Ekstrak etanol 96% tanaman tali putri diuji pada konsentrasi 0,75%, 1,5%, 3%, 6%, 9%, 12%. Hasil uji aktivitas ekstrak etanol 96 % tanaman tali putri terhadap S. aureus pada konsentrasi ekstrak 0,75% , 1,5%, 3%, 6%, 9%, 12% masing-masing memiliki diameter hambat (clear zone) rata-rata adalah 6,3 mm, 6 mm, 5 mm, 4,3 mm, 3,9 mm, dan 3,1 mm. Sedangkan hasil uji aktivitas ekstrak etanol 96 % tanaman tali putri terhadap P. acnes pada konsentrasi ekstrak 0,75% , 1,5%, 3%, 6%, 9%, 12% masing-masing memiliki diameter daya hambat (clear zone) rata-rata adalah 1,1 mm, 8,2 mm, 2,6 mm, 2,95 mm, 2,87 mm, dan 5,72 mm. Aktivitas hambatan ekstrak etanol 96% tali putri terhadap bakteri S. aureus dan P. Acne terlihat pada konsentrasi 0.75% dengan diameter daya hambat masing-masingnya adalah 6,3 mm dan 1,1 mm.
Assessment and predictors of HIV knowledge among vocational school adolescents in Thailand
Authors: Yau Shamsudeen , Adamu Ya′u , Wongsawat Pramote , Songthap Archin 
Published: October 2022

Background:
Despite substantial progress in the fight against human immunodeficiency virus and acquired immunodeficiency syndrome globally, it remains a threat to global adolescent health. This study assessed the level of HIV knowledge among vocational school students and identified the relevant factors.

Methods:
This was an analytical cross-sectional study conducted from August to September 2019. A total of 345 students aged 15 to 19 years were selected from three vocational schools in Phitsanulok Province, Thailand, using a multistage random sampling technique. The HIV Knowledge Questionnaire (18 item version) was used to collect the data, which were analysed by mean, frequency, Chi- square and binary logistic regression.

Results:
Only 38.8% of participants were fully aware of HIV knowledge; five individual items showed a significant difference in knowledge of HIV between males and females; two items relating to HIV prevention knowledge (P=0.021, 0.009); two items relating HIV transmission (P=0.028, 0.035); one item relating to HIV diagnosis (P=0.008). Factors that were significantly associated with HIV knowledge included gender (male vs. female, OR 1.83, 95% CI 1.01-3.34), residence (sub-district municipality area vs. sub-district of administrative organization area, OR 0.44, 95% CI 0.23-0.84), education (2nd and 3rd academic year vs. 1st, OR 7.00, 95% CI 2.40-20.41; OR 6.40, 95% CI 2.05-20.01) and source of income (from both parents vs. self, OR 0.07, 95% CI 0.04-0.64).

Conclusions:
There are serious deficits and disparities in the knowledge of male and female adolescents on HIV transmission, prevention and diagnosis, and there is a need to expand the provision of gender-focused sexual health education programs.
Helicobacter pylori infection in a multi-ethnic population in east coast of Borneo, Malaysia
Authors: Lee Ooi-Cheng , Lai Chung-Ket 
Published: October 2022

Objective:
To determine the prevalence of Helicobacter (H.) pylori infection among the population of east coast of Borneo and explore the relationship between demographic factors, ethnicity and risk of H. pylori infection.

Methods:
This cross-sectional study enrolled 211 patients who underwent elective oesophagogastroduodenoscopy in 2017. Demographic data, endoscopic indications as well as the results of the mucosal biopsy were obtained and analysed from the endoscopy unit registry.

Results:
A total of 211 patients from 14 ethnic groups were enrolled in the study, most of were Chinese (28.4%), followed by Dusun (14.7%) and Songgai (13.7%). Overall, the period prevalence for 2017 was 44.5%. Multivariate logistic regression analysis showed an association between ethnicity and H. pylori. Bajau (adjusted odds ratio=5.612, P=0.005) and Dusun ethnic groups (adjusted odds ratio=7.359, P=0.001) were at a significantly higher risk of H. pylori infection compared to Chinese. However, the regression model only explained 11.6% (Cox & Snell Pseudo R2) of the prevalence of H. pylori infection.

Conclusions:
The period prevalence for 2017 was 44.5%, with certain indigenous ethnic groups having a higher risk than others. Clinicians should consider obtaining further history regarding the ethnic's culture and dietary practice prior to starting H. pylori eradication therapy.
Characteristics of post-Wuhan COVID-19 outbreaks in mainland China
Authors: Li Yifan , Guo Cheng , Wu Qin , Guo Zhongmin 
Published: October 2022

Objective:
To review the characteristic of Coronavirus disease 2019 (COVID-19) outbreaks in mainland China, particularly post-Wuhan outbreaks, and to help design effective responses in the foreseeable future.

Method:
The data regarding COVID-19 outbreaks between December 2019 and March 16, 2022 were obtained from China's publicly available databases. The data were analyzed using descriptive statistics. Five outbreak stages were defined according to distinct epidemiological characteristics across different time periods over the past two years.

Result:
Since the 2020 Wuhan outbreak, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) local infections were confirmed in 37 995 cases as of March 16, 2022. We identified 285 isolated outbreaks in unrelated people that occurred in four additional distinct stages, over 57% of which had been imported, such as imported infected travelers and fomite transmission. The basic reproduction number (R0) of original SARS-CoV-2 was about 2.79, while the Delta variant was about 5.08 and Omicron was 7.0 or greater, resulting in the disease being more contagious during the fourth (Delta) and fifth (Omicron) stages than previous stages.

Conclusion:
China has experienced various COVID-19 outbreaks of different levels since the start of the pandemic in Wuhan, and local transmission is mainly caused by imported sources. If the “dynamic COVID-zero” policy is not appropriately followed, it will be difficult to contain the spread in China from overseas and to cope with the Omicron variant.
Therapy
Authors: Amin Nikhitha , Shenoy Manjunath Mala , Keekan Kishore Kumar , Pai Vidya , Halady Dinesh Kamath , Kanavu Narasimha Sharma , Killur Lokesh Rao Bangady , Ganesha Katara Krishna 
Published: October 2022

Background:
There is a high frequency of recurrent, chronic, and therapy-resistant dermatophyte infections reported from India.

Objectives
The study was carried out to identify the epidemiologic factors, clinical features, and causative agents associated with therapy-resistant tinea corporis.

Subjects and Methods
Patients above 18 years of age, diagnosed by dermatologists, and received systemic therapy for at least 3 weeks with inadequate response or relapsed within 4 weeks of cessation of therapy were taken for the study. Demography, clinical features, and results of mycological examination were retrieved.

Results
A total of 64 (33.7%) patients were included after screening 190 patients. There were 33 (51.6%) males and 31 (48.4%) females, and most patients (51, 79.7%) were young adults (18–45 years). Family history was obtained in 50 (78.1%) patients. Tinea cruris was associated in 50 (78. 1%) and tinea faciei in 15 (23.4%) of cases. Topical corticosteroids were used by 46 (71.87%) patients in the past. The past therapy with oral itraconazole (46 cases, 56.25%) was the most common to be used. Comorbidities were found in 7 (10.9%) patients. Trichophyton mentagrophytes in 55 cases (85. 9%) was the most common isolate followed by Trichophyton rubrum (7, 10.9%) cases associated with therapy-resistant tinea corporis.

Conclusion
Therapeutic failure is alarmingly common in the current scenario of dermatophytosis in India. Failure is probably seen with all common isolates but the most common among T. mentagrophytes. Younger patients, high contagious nature, and concomitant tinea faciei may be associated with a higher risk of therapy resistance.
A retrospective time-to-event analysis on COVID-19 patients using integrated medicine (Allopathy and Siddha medicine)
Authors: Saraswathi Kolappan Nalina , Sathyarajeswaran Parameswaran , Vinod Nalupalil Purushothaman , Narayanababu Ramanujam , Parthiban Paneerselvam , Ganesh Subramaniyam 
Published: October 2022

Background:
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a single-stranded RNA virus that causes SARS. The virus was originally called SARS-CoV-2 named officially by the World Health Organization as COVID-19 and a global health emergency.

Aim:
The aim of this article is to assess various clinical findings, comorbidities, and outcomes including periods of hospital stay of asymptomatic/symptomatic COVID-19 patients admitted at the Government Medical College, Omandurar, Chennai District of Tamil Nadu state and those who were under Integrated Medical care of hydroxychloroquine and Kabasura Kudineer.

Materials and Methods:
This study is a retrospective cross-sectional study on 162 asymptomatic/symptomatic laboratory-confirmed SARS-CoV-2-infected patients from both sexes and all age groups, admitted to the Government Medical College, Omandurar, Chennai District of Tamil Nadu state, India from March 30, 2020 to April 30, 2020.

Results:
SARS-CoV-2 confirmed 162 patients: 114 (70.4%) males and 48 (29.6%) females participated in the study. About 37.7% of the participants belonged to the age group of 26–40 years, 32.7% belonged to the age group 41–60 years, 16% belonged to the age group 13–25 years, 9.9% belonged to the age group greater than 60 years, and 3.7% belonged to the age group of 0–12 years. Around 16.7% have comorbidities, whereas the remaining 83.3% were free from comorbid conditions. All participants were given Kabasura Kudineer, but the treatment of allopathy medicine intake varies from person to person depending on their health status and disease severity. Abdominal computed tomography scan or chest X-rays of 24 (14.8%) patients were done during the study period. Two patients died and two were referred to another hospital, remaining 97.5% completely recovered from the viral infection. Admission days varied from 1 to 23 days. The overall median length of stay was 16 days based on this study.

Conclusion:
This study reveals that 97.5% of the patients were completely recovered from the viral infection and both average and median hospital stay is 16 days.
Review on siddha poly herbal formulation Avuri Karpam for Keelvatham
Authors: Thamarai Selvan Giftillda Selva Elsee , Muthiah Manikgantan Erulandy , Govindaraju Bharathkumar 
Published: October 2022

Introduction:
Siddha system of medicine is an integrated part of Indian system, which is very potent and unique system. Treating disease with natural ingredient gives cost effective and less adverse drug reactions. Herbal formulations which are mentioned in Siddha text are helpful in the treatment of various diseases. Avuri Karpam is a poly herbal formulation which has 7 ingredients and it is mentioned in Siddha classical literature “Pathartha Guna Vilakkam”.

Materials and Methods:
All ingredients of the drug Avuri Karpam is briefly explained here in Siddha aspects, Actions, Chemical constituents, Pharmacolgical aspects. All the above informations were collected from various scientific articles.

Results:
This article provides a systematic review examined the effects of Siddha treatment for treating arthritis and also various diseases through Avuri Karpam and its active substances present in plants and their actions in a scientific way. However further clinical study is needed to prove the standard of the drug worldwide.

Conclusion:
It could be a choice of drug for treating arthritis in cost effective less adverse drug reactions.
A review of catholic men organisation (cmo) the history of st. Paul parish, university of calabar: my life as a catholic faithful, 2021 international father’s day celebration essay- writing competition results, 12th june, 2021
Authors: Eno Grace Nta,  
Published: October 2022

INTRODUCTION
The Catholic Men Organisation (CMO) is one of the four major organisations in the Church, the others being Catholic Women Organisation (CWO), Nigerian Federation of Catholic Students (NFCS) and Holy Childhood Association. The CMO is the pillar of the Church and as its motto, “Christ is our Leader” provides exemplary leadership in the Church. Members of the CMO are heads of their various families and understand the need to plan for every member of the family. Since 2006 when the first International father’s Day celebration took place in St Paul, children and students have played a key role. They have entertained the Parish with traditional dance displays, and had essay-writing competitions in 2007 and 2021. In addition, three undergraduate students enjoyed scholarship awards in 2021. Of course, the focus on students and children is not surprising since St. Paul is a predominantly student parish otherwise usually referred to as the Wisdom Parish.
Comparison of the expression of GATA-3 protein from the transcription factor family and pathological prognostic parameters in invasive ductal carcinomas of the breast
Authors: PARLAK Leymune , KANDEMİR Olcay 
Published: October 2022

Background GATA binding protein 3 (GATA-3) is one of the six transcription factor family members and is important for glandular development in the breast. Its expression becomes important in breast cancer. We aimed to compare GATA-3 immunoreactivity and pathological prognostic factors in patients with invasive ductal carcinoma.
Material and Methods Our study was conducted retrospectively with 300 breast invasive ductal carcinoma patients who were operated on in our hospital between May 2013 and June 2014. Patient reports, slides and blocks in the pathology archive were scanned. GATA-3 immunohistochemical (IHC) staining was evaluated according to the nuclear staining, intensity and percentage. The relationship between clinicopathological prognostic parameters and GATA-3 IHC staining results was investigated.
Results A positive staining was observed in 286 (95.3%) cases. According to the GATA-3 staining intensity and percentage, 210 (70%) cases stained strongly and 246 (82%) stained +4, respectively. There was a significant relationship between GATA-3 immunoreactivity with ER, PR, Cerb-B2, Ki-67, mitotic degree, mitotic count and histological grade.
Conclusions There was a correlation between the high expression of GATA-3 and good prognostic markers. Hormone receptors can be evaluated with Cerb-B2 and Ki-67 and used as prognosis determinants in breast cancers. They can be used to identify both primary and secondary breast tumors.
Paraoxonase Activity an Independent Contributor in SARS-CoV-2 Infection
Authors: MOGAREKAR Mukund R , RAJAN Pushpa , DHABE Mahendrakumar G , ZINE Rahul M 
Published: October 2022

Background The aim of the present study was the estimation of serum paraoxonase (PON1) activity in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Material and Methods In this cross-sectional study we estimated serum paraoxonase activity in 73 patients with SARS-CoV-2 infection and 73 healthy controls.
Results The results showed that PON1 activity was significantly decreased in patients with SARS-CoV-2 (1.30±0.55 kU/L) than in healthy controls (1.913±0.48 kU/L, p
Comparison of Hemophagocytic Lymphohistiocytosis Diagnostic Criteria in Malignancy-Associated Hemophagocytic Lymphohistiocytosis Patients
Authors: KIRKIZLAR Hakkı Onur , ALP KIRKIZLAR Tuğcan , DEMİRCİ Ufuk , KARAMAN GULSARAN Sedanur , BAS Volkan , UMİT Elif , DEMİR Ahmet Muzaffer 
Published: October 2022

Background Fulfilling diagnostic criteria of hemophagocytic lymphohistiocytosis (HLH) is challenging due to unavailable laboratory tests. Hence, we aimed to reveal malignancy-associated-HLH (M-HLH) patients in our center, which can not be reached in all tests.
Material and Methods Nine patients with M-HLH were analyzed retrospectively.
Results The median age was 59 years. The distribution of the underlying diseases was like diffuse large B cell lymphoma in 3 patients, acute myeloid leukemia in 2 patients, Hodgkin lymphoma in 2 patients, T cell non-Hodgkin lymphoma in 1 patient, and small cell lung cancer in 1 patient. According to HLH-2004 diagnostic criteria except for soluble CD25 and natural killer activity tests; one patient had 3/6, six patients had 5/6, two patients had 6/6 criteria while the median H-score was 258 at diagnosis. According to Tamamyan et al’s criteria; at the diagnosis, all patients had ≥7 (between 7-12) of 18 parameters. Patients fulfilled ≥5 parameters a median of 15 days (3-52 days) before the diagnosis and on that time six patients had 3/6 criteria of HLH-2004. 88.8% of the patients died. The median duration of survival was 8.5 days (1-18 days).
Conclusions Unavailability of the tests in some countries and centers as in ours results in complications to fulfill 5 of 8 criteria and being delayed in diagnosis and treatment. We need to develop more specific and accessible criteria, and grading systems for M-HLH diagnose.
General Characteristics of Palliative Care Patients Admitted to the Emergency Department
Authors: YILMAZ Ahmet Münir , ÇIKRIKLAR Halil İbrahim , DURAK Vahide Aslıhan , KURTOĞLU Burak , ATMACA Serhat , ERAYBAR Suna , SEÇKİN Feyzullah Faruk , ÇELEBİ Hakan , ARMAGAN Erol 
Published: October 2022

Background This study aimed to analyze patients who apply to emergency services and need palliative care regarding appropriate patient care and effective use of health institutions.
Materials and Methods The study was conducted prospectively on patients who applied to the emergency services of Bursa Uludag University Health Application and Research Center, Health Sciences University Bursa Yüksek Ihtisas Training and Research Hospital and Bursa City Hospital between 15.08.2021 and 15.02.2022 and needed palliative care.
Results A total of 261 patients, 143 male (54.8%) and 118 female (45.2%), were included in the study. It was determined that 50 (19.1%) of these patients had previously received palliative care services. It was determined that the patients included in the study applied to the emergency services 7.52±6.77 times in the last year. The three most common diseases diagnosed in patients admitted to the emergency department were pneumonia (24.5%), urinary system infection (7.7%), and cerebrovascular disease (5.4%). Of the patients, 39.84% were referred/hospitalized, 25.28% were referred/hospitalized to intensive care units, 2.68% refused treatment, 2.68% died, and 29.5% have been discharged.
Conclusion As a result, it is understood that most of the patients in need of palliative care do not receive this service, and patients who can be treated in palliative care units are treated in clinics and intensive care units.
Decentralized adaptive control applied to two links of a five degrees of freedom robot, using the polynomial technique
Authors: Riul José Antonio , Montenegro Paulo Henrique de Miranda , Pinto Carlos Roberto Alves 
Published: October 2022

The objective of this work is to design and implement decentralized adaptive controllers in order to perform the position control of two links of an electromechanical manipulator robot with five degrees of freedom (DOF 5). The manipulator robot is consisted of five rotational joints, four links and a claw. Five DC motors are used to drive the robot and the motion transmission from the motors to the joints is achieved by gear trains. Models of the manipulators robots are obtained using Newton-Euler or Lagrange equations; and are coupled and nonlinear. In this work, the model of the links of the manipulator robot is obtained in real time for each sampling period. The parameters of the links to be controlled are identified by recursive least squares (RLS) method, according to data from the links, and are used in the designs of adaptive controllers for the positions control of the joints of the links under analysis. In the end, the experimental results are presented, like the evaluation of the performance achieved by the manipulator robot links.
Requalificação urbanística sustentável da orla do município de Itacoatiara / AM
Authors: Bonecker Camila Josely Lekakis , Ribeiro Rômulo José da Costa 
Published: October 2022

O município de Itacoatiara, no Estado do Amazonas, sofre o processo de degradação da paisagem urbana. Requalificar a orla do município seria um grande benefício para toda a população e a paisagem da cidade, tornando a vista de um dos maiores rios do mundo, muito mais bela e funcional. O trecho da orla abordado neste estudo localiza-se no Bairro do Jauari, onde há uma demanda elevada de pedestres, ciclistas, motociclistas, motoristas, carregadores, feirantes e embarcações com passageiros e mercadorias. Com base em adaptações dos indicadores de mobilidade urbana sustentável, IMUS, foi possível projetar uma setorização, eliminando as deficiências locais da área e realizando a requalificação urbanística sustentável, prevendo desapropriações extremamente necessárias e um conceito apropriado para os meses de vazante e enchente na região, buscando e implantando os princípios de planejamento urbano, de acessibilidade e mobilidade urbana sustentável, permitindo o lazer, o conforto, a segurança, a acessibilidade e a mobilidade.
Pengembangan Hybrid Learning Model Pada Pembelajaran Ipa Di Sekolah Penyelenggara Pendidikan Inklusif
Authors: Hidayat Hidayat 
Published: October 2022

Pembelajaran di masa pandemi covid-19 diperlukan upaya untuk mengatasi learning loss, sebagai upaya untuk mengeliminasi dampak tersebut adalah dengan menerapkan model pembelajaran hybrid . Penulisan ini bertujuan mengembangkan model pembelajaran secara tatap muka dan secara jarak jauh secara langsung. Metode penelitian adalah research and development model ADDIE. Sumber data penelitian ini adalah peserta didik kelas 6 SDN Pulau Kelapa 02 Pagi tahun Pelajaran 2020/2021 dan terdapat dua peserta didik berkebutuhan khusus. Instrumen yang digunakan adalah observasi, wawancara dan tes kelayakan dengan subjek penelitian adalah guru dan peserta didik . Hasil penelitian diperoleh gambaran tentang kelayakan pengembangan model pembelajaran hybrid yang diterapkan di sekolah dasar bahwa model campuran ini layak diterapkan di jenjang SD yang menyelenggarakan pendidikan inklusif dengan memanfaatkan berbagai aplikasi seperti google classroom, zoom dan dilaksanakan dengan moda tatap muka secara langsung. Hasil penelitian diperoleh bahwa nilai efektivitas model hybrid dalam pembelajaran yang dapat mengurangi keterbatasan peserta didik dalam menerima pembelajaran di masa pandemi. Hasil kelayakan dari produk ini berdasarkan para ahli materi sebesar 87% yang termasuk ke dalam kategori “baik”, sedangkan uji kelayakan pada ahli media sebesar 91% yang termasuk ke dalam kategori “sangat baik”. Kesimpulan dari hasil penelitian dan pengembangan tersebut adalah penggunaan model pembelajaran hybrid dapat membantu peserta didik memahami konsep pembelajaran di masa pandemi dengan teknik campuran antara metode jarak jauh dan tatap muka secara bersamaan yang terdiri dari 50% peserta didik di rumah dan 50% peserta didik di sekolah.