bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Model Problem Based Learning (PBL) Berbantuan Media Si Bula (Stik Bilangan Bulat) Terhadap Hasil Belajar Matematika Siswa SD Kelas IV SDN 18 Cakranegara Tahun Ajaran 2021/2022
Authors: Zulva Maya , Turmuzi Muhammad , Saputra Heri Hadi 
Published: June 2022

Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan model Problem Based Learning (PBL) berbatuan media Si Bula (Stik Bilangan Bulat) terhadap hasil belajar siswa kelas IV SDN 18 Cakranegara Tahun Pelajaran 2022. Jenis penelitian yang digunakan adalah penelitian eksperimen dengan desain penelitian Quasi Eksperimen Design tipe Nonequivalent Control Group Design. Subyek penelitian ini adalah siswa kelas IV A yang merupakan kelas eksperimen yang diberikan perlakuan berupa pembelajaran menggunakan model model Problem Based Learning (PBL) berbatuan media Si Bula (Stik Bilangan Bulat), sedangkan kelas IV B merupakan kelas kontrol yang tidak diberikan perlakuan khusus. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah tes berupa tes pilihan ganda dan lembar observasi aktivitas mengajar guru. Data yang diperoleh diuji dengan menggunakan uji t (t-polled varian). Berdasarkan hasil belajar matematika siswa pada materi penjumlahan dan pengurangan bilangan bulat pada tahap post-test diperoleh nilai rata-rata pada kelas eksperimen adalah 72,08 dan kelas kontrol adalah 60,42. Hasil pengujian hipotesis diperoleh hasil thitung sebesar 2,070 dan tTabel 2,014 pada taraf signifikansi 0,05 atau 5%, sehingga dapat diketahui thitung >tTabel. Sesuai dengan kriteria pengujian menunjukkan bahwa Ha dinyatakan diterima dan H0 dinyatakan ditolak. Maka dapat disimpulkan bahwa ada pengaruh yang signifikan dalam penggunaan model Problem Based Learning (PBL) berbatuan media Si Bula (Stik Bilangan Bulat) terhadap hasil belajar matematika siswa kelas IV SDN 18 Cakranegara Tahun Ajaran 2021/2022.
AHMET REMZİ DEDE (AKYÜREK) HAYATI (1872-1944) VE TASAVVUFÎ / EDEBÎ YÖNÜ
Authors: ÖZTÜRK Nuran 
Published: June 2022

Kayserili Ahmet Remzi (Akyürek) Bir “Mevlevî Dede”sidir. Yaşadığı dönem itibarıyla Osmanlı Devleti’nin sonuna ve Cumhuriyet’in ilk 20 yılına tanıklık etmiştir. Bu yüzden onun hayat hikâyesi ve şiirleri, hem edebiyat ve kültür tarihi hem de yakın dönemin sosyal ve siyasî tarihi açısından önemlidir. Taşıdığı Osmanlı bakiyesi vasıflarının pek çoğunu Cumhuriyet döneminde devam ettirememek durumunda kalmıştır. Geçiş döneminin uyum ve sancılarını yaşayan bu zatın gelecek nesiller için canlı bir tarih portresi olarak aktarılmasının yararlı olacağı varsayılmış ve bu yazı kaleme alınmıştır.
Ahmet Remzi Dede’nin hayatına ilişkin bilgilerin önemli bir kısmı biyografik kaynaklarda yahut hakkında yapılan günümüze kadarki çeşitli yayınlarda farklılık göstermektedir. Söz konusu bilgi farklılıkları, şiirleri ile karşılaştırılmış ve bir tenkit süzgecinden geçirilerek aktarılmıştır. Ahmet Remzi Dede’nin hayatı hakkındaki bilgiler ailesi, eğitimi, memuriyetleri alt başlıkları ile ele alınmış; tasavvufî ve edebî yönü ise mutasavvıf kimliği, siyasetle ilişkisi ve edebî kimliği başlıkları altında değerlendirilmiştir. Daha önce yazılanlardan istifade edilmekle birlikte, Şairliği başlığı altında şiirlerinden seçilen örnekler üzerinden daha önce bahsedilmeyen hususlara da değinilmiştir. Fakat bu çalışmayı asıl özgün kılacak olan, Ahmet Remzi Dede’nin “ara/köprü nesil” denilebilecek yönünün belirlenmeye çalışılmasıdır.
Soft connectivity and soft θ-connectivity relative to a soft topological space
Authors: Al Ghour Samer 
Published: June 2022

Let (Y, σ, B) be a soft topological space. We introduce two new classes of soft subsets of (Y, σ, B): soft connectedness relative to (Y, σ, B) and soft θ-connectedness relative to (Y, σ, B). We show that the class of soft connected subsets relative to (Y, σ, B) includes the class of soft θ-connected subsets relative to (Y, σ, B), but that these two classes do not always coincide. However, they coincide when (Y, σ, B) is soft regular. We have provided several properties for each of these classes of soft sets. As two main results, we prove that for a given soft function fpu : (Y, σ, B) ⟶ (Y, σ, B) and a soft subset H of (Y, σ, B), the soft set fpu (H) is θ-connected relative to (Y, σ, B) if (fpu is soft weakly continuous and H is connected relative to (Y, σ, B)) or (fpu is soft θ-continuous and H is θ-connected relative to (Y, σ, B)). Also, we investigate the correspondence between our new concepts in a soft topological space and their corresponding topological spaces properties. Moreover, we provide some examples to illustrate the obtained results and relationships.
PENGARUH INDEPENDENSI, KOMPETENSI, DAN PENGETAHUAN TERHADAP KUALITAS AUDIT DI INSPEKTORAT DAERAH ISTIMEWA YOGYAKARTA
Authors: Senapan Dyah Widiyatri , Senapan Sucahyo Heriningsih , Senapan Sriyono 
Published: June 2022

Kualitas audit sangat penting dalam melakukan kegiatan audit karena dengan kualitas audit yang baik akan menghasilkan laporan hasil yang dapat dipercaya dan apa adanya tanpa ada pengaruh dari pihak yang berkaitan. Untuk mendapatkan kualitas audit dalam instansi pemerintah sering terkendala, karena kurangnya pengawasan, kurangnya sumber daya manusia, independensi dan pengetahuan auditor. Penelitian ini bertujuan untuk mengetahui pengaruh positif independensi kompetensi dan pengetahuan secara parsial terhadap kualitas audit di Inspektorat Daerah Istimewa Yogyakarta. Populasi pada penelitian ini adalah seluruh pegawai Inspektorat Daerah Istimewa Yogyakarta. Sedangkan sampel penelitian ini adalah auditor Inspektorat Daerah Istimewa Yogyakarta yang berjumlah 43 pegawai. Teknik pengambilan sampel adalah Purposive sampling. Penelitian ini menggunakan data primer dengan cara melakukan survei melalui penyebaran kuesioner. Responden dalam penelitian ini berjumlah 43. Metode analisis data menggunakan analisis regresi linear berganda. Hasil penelitian menujukkan bahwa Independensi berpengaruh positif dan signifikan terhadap kualitas audit. Kompetensi berpengaruh positif dan signifikan terhadap kualitas audit. Pengetahuan berpengaruh positif dan signifikan terhadap kualitas audit.
Formação de hábitos alimentares na primeira infância
Authors: Leão Jéssica Ingrid da Silva , Queiroz Myrelli Foster Mello de , Freitas Francisca Marta Nascimento de Oliveira , Ferreira José Carlos de Sales 
Published: June 2022

Introdução: Para o desenvolvimento de qualquer ser humano acontecer de forma saudável, há fatores internos que são genéticos e fatores externos que são relacionados a hábitos alimentares familiares, culturais e socioeconômicos; onde a alimentação é base para o desenvolvimento humano e tem suas repercussões ao longo de toda existência do indivíduo. Objetivo: Descrever a influência da alimentação saudável na fase da introdução alimentar. Metodologia: Trata-se de uma revisão bibliográfica com abordagem descritiva. Resultados: A partir do estudo de literatura foi possível observar a importância de uma de bons hábitos alimentares e que estes se levados corretamente em todas as fases da vida, pode favorecer uma melhor qualidade de vida para qualquer indivíduo. Discussão dos resultados: Apresentou-se a importância da amamentação, os métodos mais comuns utilizados na introdução alimentar após os 6 meses a efetiva correlação da influência da família e da escola nas escolhas alimentares da criança, bem como a prevenção de possíveis doenças. Conclusão: Podemos concluir que uma alimentação saudável e equilibrada, com o consumo adequado de frutas, hortaliças e alimentos ricos em nutrientes, desde o início da introdução alimentar da criança, irá desenvolver hábitos saudáveis que podem ser levados para toda a vida.
Análise logística na produção de grãos no Brasil
Authors: Nascimento Vinícius Vicente Frazão do , Pereira Guilherme Fragoso Xavier , Melo Carlos Cicinato Vieira , Freire Ana Izabella , Souza Filipe Bittencourt Machado de , Martins Athila Damasceno 
Published: June 2022

O Brasil ocupa posição relevante na produção de alimentos oriundos do agronegócio, em culturas como milho, soja e café. Entretanto, a logística é um dos maiores problemas da produção de brasileira de alimentos e, mais especificamente, de grãos. O objetivo do trabalho foi analisar a logística da producão de grãos no Brasil que de fato influencia em toda cadeia de produtiva. A logística é uma atividade importante no agronegócio e apesar das dificuldades encontradas como a falta de investimentos, é uma etapa que contribui ao país em termo de economia. O sistema de transporte é essencial para a movimentação da economia do país, sem ele os produtos não chegariam aos consumidores, as indústrias não teriam acesso as matérias primas e nem teriam condições de escoar sua produção. É um setor que viabiliza todos os outros setores. Além disso, o transporte agrega na qualidade dos serviços logísticos, pois impacta, diretamente, no tempo de entrega, na confiabilidade e na segurança dos produtos. A escolha do modal de transporte a ser utilizado é de extrema importância e apesar do agronegócio ser forte no Brasil, ainda encontram-se muitas dificuldades para o transporte da carga. Existem vários tipos de modais, porém nem todos eles são utilizados, sendo o rodoviário o principal deles. O País possui a quarta maior malha rodoviária do mundo, mas grande parte não é pavimentada. O Brasil necessita de planejamento e investimento para sanar a problemática da matriz logística de transporte.
Lecturer Performance Information Systems Based on IAPS 4.0
Authors: Yang Yang Agita Rindri , Rollastin Boy 
Published: June 2022

Currently, the lecturer performance data based on IAPS 4.0 at Polman Babel are still not integrated yet and still collected in Microsoft Excel. This study aims to develop Lecturer Performance Information Systems Based on IAPS 4.0 that can assist the preparation and management of IAPS 4.0-based lecturer performance. This study follows the Systems Development Life Cycle includes planning and preparation, system analysis, system design, development, testing, and deployment. The system is developed using PHP programming language, MySql database, Codeigniter Framework, Bootstrap Framework for CSS, and the Guzzle library to create a REST Client that accesses the Google Scholar REST API. System testing in this study uses black-box testing to test system functionality. The functionality testing shows that the functionality of the system is 100% successful and accepted by stakeholders.
Improving Control of Gene Therapy-Based Neurotrophin Delivery for Inner Ear Applications
Authors: St. Peter Madeleine , Brough Douglas E. , Lawrence Anna , Nelson-Brantley Jennifer , Huang Peixin , Harre Jennifer , Warnecke Athanasia , Staecker Hinrich 
Published: June 2022

Background: Survival and integrity of the spiral ganglion is vital for hearing in background noise and for optimal functioning of cochlear implants. Numerous studies have demonstrated that supplementation of supraphysiologic levels of the neurotrophins BDNF and NT-3 by pumps or gene therapy strategies supports spiral ganglion survival. The endogenous physiological levels of growth factors within the inner ear, although difficult to determine, are likely extremely low within the normal inner ear. Thus, novel approaches for the long-term low-level delivery of neurotrophins may be advantageous.Objectives: This study aimed to evaluate the long-term effects of gene therapy-based low-level neurotrophin supplementation on spiral ganglion survival. Using an adenovirus serotype 28-derived adenovector delivery system, the herpes latency promoter, a weak, long expressing promoter system, has been used to deliver the BDNF or NTF3 genes to the inner ear after neomycin-induced ototoxic injury in mice.Results: Treatment of the adult mouse inner ear with neomycin resulted in acute and chronic changes in endogenous neurotrophic factor gene expression and led to a degeneration of spiral ganglion cells. Increased survival of spiral ganglion cells after adenoviral delivery of BDNF or NTF3 to the inner ear was observed. Expression of BDNF and NT-3 could be demonstrated in the damaged organ of Corti after gene delivery. Hearing loss due to overexpression of neurotrophins in the normal hearing ear was avoided when using this novel vector–promoter combination.Conclusion: Combining supporting cell-specific gene delivery via the adenovirus serotype 28 vector with a low-strength long expressing promoter potentially can provide long-term neurotrophin delivery to the damaged inner ear.
Direct and Sensitive Electrochemical Detection of Bisphenol A in Complex Environmental Samples Using a Simple and Convenient Nanochannel-Modified Electrode
Authors: Huang Jie , Zhang Tongtong , Dong Guotao , Zhu Shanshan , Yan Fei , Liu Jiyang 
Published: June 2022

Rapid, convenient, and sensitive detection of Bisphenol A (BPA) in complex environmental samples without the need for tedious pre-treatment is crucial for assessing potential health risks. Herein, we present an electrochemical sensing platform using a simple nanochannel-modified electrode, which enables the direct and sensitive detection of BPA in complex samples. A vertically ordered mesoporous silica-nanochannel film (VMSF) with high-density nanochannels is rapidly and stably grown on the surface of a electrochemically activated glassy carbon electrode (p-GCE) by using the electrochemically assisted self-assembly (EASA) method. The high antifouling capability of the VMSF/p-GCE sensor is proven by investigating the electrochemical behavior of BPA in the presence of model coexisting interfering molecules including amylum, protein, surfactant, and humic acid. The VMSF/p-GCE sensor can sensitively detect BPA ranged from 50 to 1.0 μM and 1.0–10.0 μM, with low detection limits (15 nM). Owing to the electrocatalytic performance and high potential resolution of p-GCE, the sensor exhibits high selectivity for BPA detection in the presence of common environmental pollutants, including bisphenol S (BPS), catechol (CC), hydroquinone (HQ), and 4-nitrophenol (4-NP). In combination with the good antifouling property of the VMSF, direct detection of BPA in environmental water samples and soil leaching solution (SLS) is also realized without separation pretreatment. The developed VMSF/p-GCE sensor demonstrated advantages of simple structure, high sensitivity, good antifouling performance, and great potential in direct electroanalysis of endocrine-disrupting compounds in complex samples.
Electrocatalytic Reduction of Nitrate via Co3O4/Ti Cathode Prepared by Electrodeposition Paired With IrO2-RuO2 Anode
Authors: Wang Chuan , Cao Zhifen , Huang Hongtao , Liu Hong , Wang Sha 
Published: June 2022

Nitrate pollution is already a global problem, and the electrocatalytic reduction of nitrate is a promising technology for the remediation of wastewater and polluted water bodies. In this work, Co3O4/Ti electrodes were prepared by electrodeposition for the electrocatalytic reduction of nitrate. The morphology, chemical, and crystal structures of Co3O4/Ti and its catalytic activity were investigated. Then, the electrocatalytic nitrate reduction performance of Co3O4/Ti as the cathode was evaluated by monitoring the removal efficiencies of nitrate (NO3−-N) and total nitrogen (TN), generation of reduction products, current efficiency (CE), and energy consumption (EC) at different operating conditions. Under the catalysis of Co3O4/Ti, NO3− was reduced to N2 and NH4+, while no NO2− was produced. After the introduction of chloride ions and IrO2-RuO2/Ti as the anode, NH4+ was selectively oxidized to N2. The removal efficiencies of NO3−-N (at 100 mg/L) and TN after 2 h were 91.12% and 60.25%, respectively (pH 7.0; Cl− concentration, 2000 mg/L; current density, 15 mA/cm2). After 4 h of operation, NO3−-N and TN were completely removed. However, considering the EC and CE, a 2-h reaction was the most appropriate. The EC and CE were 0.10 kWh/g NO3−N and 40.3%, respectively, and electrocatalytic performance was maintained after 10 consecutive reduction cycles (2 h each). The cathode Co3O4/Ti, which is prepared by electrodeposition, can effectively remove NO3−-N, with low EC and high CE.
Synthesis of MeOH and DME From CO2 Hydrogenation Over Commercial and Modified Catalysts
Authors: Santiago Rafaelle G. , Coelho Juliana A. , Lucena Sebastião M. P. de , Musse Ana Paula S. , Portilho Marcio de F. , Rodriguez-Castellón Enrique , Azevedo Diana C. S. de , Bastos-Neto Moises 
Published: June 2022

Growing concern about climate change has been driving the search for solutions to mitigate greenhouse gas emissions. In this context, carbon capture and utilization (CCU) technologies have been proposed and developed as a way of giving CO2 a sustainable and economically viable destination. An interesting approach is the conversion of CO2 into valuable chemicals, such as methanol (MeOH) and dimethyl ether (DME), by means of catalytic hydrogenation on Cu-, Zn-, and Al-based catalysts. In this work, three catalysts were tested for the synthesis of MeOH and DME from CO2 using a single fixed-bed reactor. The first one was a commercial CuO/γ-Al2O3; the second one was CuO-ZnO/γ-Al2O3, obtained via incipient wetness impregnation of the first catalyst with an aqueous solution of zinc acetate; and the third one was a CZA catalyst obtained by the coprecipitation method. The samples were characterized by XRD, XRF, and N2 adsorption isotherms. The hydrogenation of CO2 was performed at 25 bar, 230°C, with a H2:CO2 ratio of 3 and space velocity of 1,200 ml (g cat · h)−1 in order to assess the potential of these catalysts in the conversion of CO2 to methanol and dimethyl ether. The catalyst activity was correlated to the adsorption isotherms of each reactant. The main results show that the highest CO2 conversion and the best yield of methanol are obtained with the CZACP catalyst, very likely due to its higher adsorption capacity of H2. In addition, although the presence of zinc oxide reduces the textural properties of the porous catalyst, CZAWI showed higher CO2 conversion than commercial catalyst CuO/γ-Al2O3.
How Parental Predictors Jointly Affect the Risk of Offspring Congenital Heart Disease: A Nationwide Multicenter Study Based on the China Birth Cohort
Authors: Zhang Man , Sun Yongqing , Zhao Xiaoting , Liu Ruixia , Yang Bo-Yi , Chen Gongbo , Zhang Wangjian , Dong Guang-Hui , Yin Chenghong , Yue Wentao 
Published: June 2022

ObjectiveCongenital heart disease (CHD) is complex in its etiology. Its genetic causes have been investigated, whereas the non-genetic factor related studies are still limited. We aimed to identify dominant parental predictors and develop a predictive model and nomogram for the risk of offspring CHD.MethodsThis was a retrospective study from November 2017 to December 2021 covering 44,578 participants, of which those from 4 hospitals in eastern China were assigned to the development cohort and those from 5 hospitals in central and western China were used as the external validation cohort. Univariable and multivariable analyses were used to select the dominant predictors of CHD among demographic characteristics, lifestyle behaviors, environmental pollution, maternal disease history, and the current pregnancy information. Multivariable logistic regression analysis was used to construct the model and nomogram using the selected predictors. The predictive model and the nomogram were both validated internally and externally. A web-based nomogram was developed to predict patient-specific probability for CHD.ResultsDominant risk factors for offspring CHD included increased maternal age [odds ratio (OR): 1.14, 95% CI: 1.10–1.19], increased paternal age (1.05, 95% CI: 1.02–1.09), maternal secondhand smoke exposure (2.89, 95% CI: 2.22–3.76), paternal drinking (1.41, 95% CI: 1.08–1.84), maternal pre-pregnancy diabetes (3.39, 95% CI: 1.95–5.87), maternal fever (3.35, 95% CI: 2.49–4.50), assisted reproductive technology (2.89, 95% CI: 2.13–3.94), and environmental pollution (1.61, 95% CI: 1.18–2.20). A higher household annual income (100,000–400,000 CNY: 0.47, 95% CI: 0.34–0.63; &gt; 400,000 CNY: 0.23, 95% CI: 0.15–0.36), higher maternal education level (13–16 years: 0.68, 95% CI: 0.50–0.93; ≥ 17 years: 0.87, 95% CI: 0.55–1.37), maternal folic acid (0.21, 95% CI: 0.16–0.27), and multivitamin supplementation (0.33, 95% CI: 0.26–0.42) were protective factors. The nomogram showed good discrimination in both internal [area under the receiver-operating-characteristic curve (AUC): 0.843] and external validations (development cohort AUC: 0.849, external validation cohort AUC: 0.837). The calibration curves showed good agreement between the nomogram-predicted probability and actual presence of CHD.ConclusionWe revealed dominant parental predictors and presented a web-based nomogram for the risk of offspring CHD, which could be utilized as an effective tool for quantifying the individual risk of CHD and promptly identifying high-risk population.
Pulmonary Vasculature Responsiveness to Phosphodiesterase-5A Inhibition in Heart Failure With Reduced Ejection Fraction: Possible Role of Plasma Potassium
Authors: Monzo Luca , Reichenbach Adrian , Al-Hiti Hikmet , Jurcova Ivana , Huskova Zuzana , Kautzner Josef , Melenovsky Vojtech 
Published: June 2022

IntroductionPhosphodiesterase-5a inhibition (PDE5i) leads to favorable changes in pulmonary hemodynamic and cardiac output (CO) in patients with advanced heart failure (HF) and reduced ejection fraction (HFrEF). The hemodynamic response to PDE5i could be heterogeneous and the clinical variables associated with these changes are scarcely investigated.Materials and MethodsOf 260 patients with advanced HFrEF referred for advanced therapies [cardiac transplant/left ventricular assist device (LVAD)], 55 had pulmonary hypertension (PH) and fulfilled the criteria for the PDE5i vasoreactivity test. Right heart catheterization (RHC) was performed as a part of clinical evaluation before and after 20-mg intravenous sildenafil. Absolute and relative changes in pulmonary vascular resistance (PVR) were evaluated to assess hemodynamic response to PDE5i. Clinical, biochemical, and hemodynamic factors associated with PVR changes were identified.ResultsSildenafil administration reduced PVR (− 45.3%) and transpulmonary gradient (TPG; − 34.8%) and increased CO (+ 13.6%). Relative change analysis showed a negative moderate association between baseline plasma potassium and changes in PVR (r = − 0.48; p = 0.001) and TPG (r = − 0.43; p = 0.005) after PDE5i. Aldosterone concentration shows a direct moderate association with PVR changes after PDE5i. A significant moderate association was also demonstrated between CO improvement and the severity of mitral (r = 0.42; p = 0.002) and tricuspid (r = 0.39; p = 0.004) regurgitation.ConclusionWe identified plasma potassium, plasma aldosterone level, and atrioventricular valve regurgitations as potential cofounders of hemodynamic response to acute administration of PDE5i. Whether modulation of potassium levels could enhance pulmonary vasoreactivity in advanced HFrEF deserves further research.