bluuebunny/crossref_metadata_2025_split huggingface dataset:
Re‐Framing Anni Albers and Bauhaus
Authors: Kim Hyunsoo 
Published: June 2022

AbstractAt this time when interdisciplinary education in higher education is in trend, the Bauhaus is in its prime again as it celebrates 100th anniversary. Anni Albers, a seminal figure in textiles, art education and modern art in America, was one of the few artists who were present in both of the experimental art colleges of the century‐ Bauhaus in Germany and Black Mountain College in the United States. Many versions of her story exist to date, however this article focuses on the version of her own story, which has not been highlighted either in media or academia. It has been widely accepted that 1) gender inequality existed in Bauhaus, 2) the shift of Albers’ medium derived from wanting recognition from the art world, and 3) a structured curriculum educated many of the artists graduated from Bauhaus. However, in this study, two oral interviews of Anni Albers, seventeen years apart, were compared with public perception, which has dominated understanding of the artist and Bauhaus for centuries. The interviews change our perspective, particularly on gender equity, craft, fine art, and curriculum at Bauhaus in the life of Anni Albers.
Protection by hydroxychloroquine prevents placental injury in obstetric antiphospholipid syndrome
Authors: Liu Jing , Zhang Liting , Tian Yijia , Wan Shuting , Hu Min , Song Shasha , Zhang Meihua , Zhou Qian , Xia Yu , Wang Xietong 
Published: June 2022

AbstractObstetric antiphospholipid syndrome (OAPS) is mediated by antiphospholipid antibodies (aPLs, and anti‐β2 glycoprotein I antibody is the main pathogenic antibody), and recurrent abortion, preeclampsia, foetal growth restriction and other placental diseases are the main clinical characteristics of placental pathological pregnancy. It is a disease that seriously threatens the health of pregnant women. Hydroxychloroquine (HCQ) was originally used as an anti‐malaria drug and has now shown benefit in refractory OAPS where conventional treatment has failed, with the expectation of providing protective clinical benefits for both the mother and foetus. However, its efficacy and mechanism of action are still unclear. After clinical data were collected to determine the therapeutic effect, human trophoblast cells in early pregnancy were prepared and treated with aPL. After the addition of HCQ, the proliferation, invasion, migration and tubule formation of the trophoblast cells were observed so that the therapeutic mechanism of HCQ on trophoblast cells could be determined. By establishing an obstetric APS mouse model similar to the clinical situation, we were able to detect the therapeutic effect of HCQ on pathological pregnancy. The normal function of trophoblast cells is affected by aPL. Antibodies reduce the ability of trophoblast cells to invade and migrate and can impair tubule formation, which are closely related to placental insufficiency. HCQ can partially reverse these side effects. In the OAPS mouse model, we found that HCQ prevented foetal death and reduced the incidence of pathological pregnancy. Therefore, HCQ can improve pregnancy outcomes and reverse the aPL inhibition of trophoblast disease. In OAPS, the use of HCQ needs to be seriously considered.
The association of specific types of vegetables consumption with 10‐year type II diabetes risk: Findings from the ATTICA cohort study
Authors: Kosti Rena I. , Tsiampalis Thomas , Kouvari Matina , Chrysohoou Christina , Georgousopoulou Ekavi , Pitsavos Christos S. , Panagiotakos Demosthenes B. 
Published: June 2022

AbstractBackgroundThe present study aimed to investigate the association between vegetable consumption, in total as well as per type/category, and 10‐year type‐2 diabetes mellitus (T2DM) incidence.MethodsThe ATTICA study was conducted during 2001–2012 in 3042 apparently healthy adults living in Athens area, Greece. A detailed biochemical, clinical, and lifestyle evaluation was performed; vegetable consumption (total, per type) was evaluated through a validated semi‐quantitative food frequency questionnaire. After excluding those with no complete information of diabetes status or those lost at the 10‐year follow‐up, data from 1485 participants were used for the current analysis.ResultsAfter adjusting for several participants' characteristics, including overall dietary habits, it was observed that participants consuming at least 4 servings/day of vegetables had a 0.42‐times lower risk of developing T2DM (hazard ratio [HR] = 0.42; 95% confidence interval [CI] = 0.29–0.61); the benefits of consumption were greater in women (HR = 0.29; 95% CI = 0.16–0.53) compared to men (HR = 0.56; 95% CI = 0.34–0.92). Only 33% of the sample consumed vegetables 4 servings/day. The most significant associations were observed for allium vegetables in women and for red/orange/yellow vegetables, as well as for legumes in men.ConclusionsThe intake of at least 4 servings/day of vegetables was associated with a considerably reduced risk of T2DM, independently of other dietary habits; underlying the need for further elaboration of current dietary recommendations at the population level.
Sex is associated with differences in oxidative stress and susceptibility to severe hepatic encephalopathy in bile‐duct ligated rats
Authors: Macedo de Oliveira Mariana , Monnet‐Aimard Alexis , Bosoi Cristina R. , Tremblay Mélanie , Rose Christopher F. 
Published: June 2022

AbstractHepatic encephalopathy (HE) is a debilitating neurological complication of chronic liver disease (CLD). Hyperammonemia plays an important role in HE's pathogenesis, acting synergistically with systemic oxidative stress. During CLD, muscle plays a compensatory role in detoxifying ammonia, and therefore muscle loss leads to an increase in the risk of developing HE. With most animal studies involving males, sex's impact on the development of CLD and associated complications such as HE and muscle loss remains unknown. Therefore, we aimed to identify the impact of sex on CLD, HE, and muscle mass loss in a rodent model of CLD. Liver injury markers, hyperammonemia, oxidative stress, muscle mass, and ammonia clearance were measured in female and male bile‐duct ligated (BDL) rats. In addition, covert HE was assessed in females while ammonia‐precipitated severe HE was assessed in female and male BDL rats, and male BDL rats treated with allopurinol (100 mg/kg), an antioxidant (xanthine oxidase inhibitor). Female BDL developed CLD and HE (impaired motor coordination and night activity) compared to respective SHAM. Hyperammonemia and muscle ammonia clearance were similar between female and male BDL. However, only female BDL rats did not develop muscle loss, brain edema, and short‐term memory impairment (vs. female SHAM) and systemic oxidative stress and decreased albumin levels (vs. male BDL). Furthermore, both female BDL and allopurinol‐treated male BDL rats were protected against ammonia‐induced overt HE. In conclusion, female and male BDL rats develop distinct features of CLD and HE, with systemic oxidative stress playing a pivotal role in the susceptibility to ammonia‐precipitated overt HE.image
Hair loss treatment and restoration: Online interest trends and video‐based social media content
Authors: Gupta Aditya K. , Hall Deanna C. 
Published: June 2022

AbstractBackgroundPublic interest in hair loss topics and treatments can be observed by examining online trends, such as those monitored by Google Trends. Social media has also gained the interest of the dermatology community. Video‐based social media sites are being used to provide the public with informational content related to hair loss and treatments, but it may not always be unbiased or reliable.AimsThis research examined the interest in hair loss and treatment related trends in recent years through Google Trends, as well as examined what videos from YouTube and TikTok that the average person may encounter when performing searches related to hair loss and treatments.ResultsGoogle Trends showed that the COVID‐19 pandemic had an initial negative impact on interests of hair loss and treatment related topics, both worldwide and in the United States. External events, such as a celebrity receiving a hair transplant, can influence the interests of the general public with the topic. The social media sites showed that there was a high level of interest in the topics, approximately 25% of videos involved a medical professional, and many involved personal experiences or natural remedies.ConclusionsInterest in hair loss and treatments continues to grow. Clinicians should do their best to follow the current public interests and be aware of where patients may be obtaining information. Being aware of general interest trends online can benefit clinicians by allowing them to prepare their clinics for potential influxes.
Types of periocular wrinkles based on anatomical and contractile characteristics of participating periocular muscles: A modified classification method and personalized injection technique
Authors: Li Yilin , Cai Lei , Zhang Xinyu , Yin Bo , Gong Xi , Li Facheng , Han Xuefeng 
Published: June 2022

AbstractBackgroundClinical classification methods for periocular wrinkles based on participating muscle behavior are lacking, and traditional treatment lacks detailed and individualized methods.AimsThis study aimed to propose a modified classification system and individualized treatment for periocular wrinkles based on the participating muscles.Patients/MethodsPeriocular wrinkles were classified into types I.I, I.II, I.III, II, and III. A personalized treatment pattern with a multipoint, low‐dose technique was developed based on wrinkle classification and severity. Standard photographs were taken and assessments made at follow‐up to evaluate wrinkle severity.ResultsWrinkle severity was reduced at 1 and 3 months after periorbital botulinum toxin injection, and no serious adverse events were recorded.ConclusionsPeriorbital wrinkles were classified according to participating muscles. The modified injection pattern was individualized, effective, and safe for the treatment of periorbital wrinkles.
Children living with long‐term conditions and their experiences of partnership in nursing care: An integrative systematic review
Authors: Barratt Macey , Bail Kasia , Paterson Catherine 
Published: June 2022

AbstractAims and ObjectiveTo describe the experiences of nursing care and partnership nursing as expressed by children living with long‐term conditions.BackgroundChildren with long‐term conditions have higher rates of hospitalisations and adverse events in hospital, yet little is known about their experiences of nursing care. How children perceive partnership in care with their families and nurses is of interest in the achievement of safe and effective careDesignAn integrative review following Joanna Briggs Institute protocols for systematic reviews.MethodAn integrative review was chosen following Joanna Briggs Institute protocols for systematic reviews. A total of 5150 articles were screened, with 251 full‐text publications reviewed. A total of 21 studies were included, three mixed‐method studies and 18 qualitative studies. This review has been reported as per Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines.ResultsFour integrated findings were identified: “Children are aware of their surroundings and needs,” “Children value positive communication,” “Children want to be recognised as an individual in the triadic relationship, and this can be done through nurses using tailored play;” and “Children seek a shared decision‐making process.”DiscussionChildren wanted to be seen as an individual in Children and Young People's nursing as well as a child who craves security, fun and comfort, both from their families and nursing staff. Children described observing partnership between nursing staff and parents but felt uninvolved, with some children craving more knowledge and power to better understand their long‐term condition.Relevance to Clinical PracticeFurther research is required on how Children and Young People's nursing staff can better support children and empower them to be active members in the shared decision‐making process if the child wishes to be involved.
Key features of adolescent inpatient units and development of a checklist to improve consistency in reporting of settings
Authors: Hayes Claire , Simmons Magenta , Palmer Victoria , Hamilton Bridget , Simons Christine , Hopwood Malcolm 
Published: June 2022

Accessible summaryWhat is known on the subject?

Little is known about adolescent inpatient units, key features which define them, and how these essential services operate and deliver care.

What the paper adds to existing knowledge?

Adolescent inpatient unit studies are limited in their descriptions of settings in terms of how they operate and key features.

The proposed preliminary checklist is a practical tool to assist clinicians, policy makers, and researchers when reporting to ensure comprehensive descriptions of adolescent inpatient settings.

What are the implications for practice?

This could be used to inform service design processes for inpatient and other mental health service models which is of critical importance in the context of reforms and implementation of these in Australia currently.

Greater attention to operational models, services, and philosophies of practice will improve reporting and allow for the advancement of knowledge, comparison of study results, and a clearer direction for mental health nursing clinicians and researchers.

AbstractIntroductionAdolescent inpatient units care for vulnerable population groups; however, little is known about how these essential services operate and deliver care.AimsTo examine the descriptions of adolescent mental health inpatient units in Australian and international research publications and to identify key features which were used to define them. A secondary aim was to develop a checklist to improve consistency when reporting on the operations and services delivered within adolescent mental health inpatient units (both public and private).MethodsFive electronic databases (CINAHL, MEDLINE, ERIC, EMBASE, and PsycINFO) were systematically searched. We included studies that provided descriptions of operations and services within adolescent inpatient units where participants had a mean age between 12 and 25. Narrative synthesis was used to explore the similarities and differences between descriptions of settings.ResultsTwenty‐eight studies were identified, which varied in their descriptions of adolescent inpatient units, providing inconsistent information to inform best practice.DiscussionStudies lack consistency and comprehensive detail when describing the operational models within inpatient units, making interpretation challenging. Consequently, a preliminary checklist is proposed to improve reporting of adolescent inpatient units.
Evolution of woody plants to the land‐sea interface – The atypical genomic features of mangroves with atypical phenotypic adaptation
Authors: Xie Wei , Guo Zixiao , Wang Jiayan , He Ziwen , Li Yulong , Feng Xiao , Zhong Cairong , Shi Suhua 
Published: June 2022

AbstractHow plants adapt and diverge in extreme environments is a key question of plant evolution and ecology. Mangrove invasion of intertidal environments is facilitated by adaptive phenotypes such as aerial roots, salt‐secreting leaf, and viviparity, and genomic mechanisms including whole genome duplication and transposable element number reduction. However, a number of mangroves lack these typical phenotypes. The question we ask is whether these phenotypically atypical mangroves also have distinct genomic features? The sibling mangrove species Lumnitzera littorea and Lumnitzera racemosa provide a model to study this question. We sequenced and assembled their genomes to chromosome level, together with a closely related species Combretum micranthum. While most mangroves have small genomes, the genomes of both Lumnitzera species are large (1443 and 1317 Mb) and carry a high proportion of repeat sequences (~75%). Moreover, Lumnitzera species have not undergone post‐gamma whole‐genome duplications. Their genome size increased mainly due to the expansion of repeat sequences in their ancestors. However, Lumnitzera genomes have reduced transposable elements by constraining the proliferation of new LTR‐RTs. Meanwhile, the two species have more gene families contracted than expanded, and some gene families with reversed size change may underlie their differentiation in root morphology and local distribution. We identified 86 chromosomal inversions, five of which are measured between 6.5 and 12.8 megabases. A number of genes located in these inversions function in pigment biosynthesis, a process likely involved in flower colour differentiation between the Lumnitzera species. We conclude that the mangroves with atypical phenotypes also have atypical genomic evolution.
Deliberate reflection and clinical reasoning: Founding ideas and empirical findings
Authors: Mamede Sílvia , Schmidt Henk G. 
Published: June 2022

AbstractContextThe idea that reflection improves reasoning and learning, since long present in other fields, emerged in the 90s in the medical education literature. Since then, the number of publications on reflection as a means to improve diagnostic learning and clinical problem‐solving has increased steeply. Recently, concerns with diagnostic errors have raised further interest in reflection. Several approaches based on reflection have been proposed to reduce clinicians' errors during diagnostic reasoning. What reflection entails varies substantially, and most approaches still require empirical examination.PurposeThe present essay aims to help clarify the role of deliberate reflection in diagnostic reasoning. Deliberate reflection is an approach whose effects on diagnostic reasoning and learning have been empirically studied over the past 15 years. The philosophical roots of the approach will be briefly examined, and the theory and practice of deliberate reflection, particularly its effectiveness, will be reviewed. Lessons learned and unresolved issues will be discussed.DiscussionThe deliberate reflection approach originated from a conceptualization of the nature of reflection practice in medicine informed by Dewey's and Schön's work. The approach guides physicians through systematically reviewing the grounds of their initial diagnosis and considering alternatives. Experimental evidence has supported the effectiveness of deliberate reflection in increasing physicians' diagnostic performance, particularly in nonstraightforward diagnostic tasks. Deliberate reflection has also proved helpful to improve students' diagnostic learning and to facilitate learning of new information. The mechanisms behind the effects of deliberate reflection remain unclear. Tentative explanations focus on the activation/reorganisation of prior knowledge induced by deliberate reflection. Its usefulness depends therefore on the difficulty of the problem relative to the clinician's knowledge. Further research should examine variations in instructions on how to reflect upon a case, the value of further guidance while learning from deliberate reflection, and its benefits in real practice.
From coping strategy to hopeful everyday practice: Changing interpretations of food self‐provisioning
Authors: Daněk Petr , Sovová Lucie , Jehlička Petr , Vávra Jan , Lapka Miloslav 
Published: June 2022

AbstractWhile alternative food networks (AFNs) have become the leading conceptualisation of sustainable food systems, vibrant scholarship on food self‐provisioning (FSP) in Central and Eastern Europe has remained confined to the geopolitical region it investigates. This article brings these two bodies of thought closer together in two steps. First, we trace four framings of FSP deployed over the last three decades—coping strategy, cultural practice, hobby and source of good food and reading FSP as transformative practice—to demonstrate its progressive affinity with AFNs. Second, we follow the most recent framing in highlighting the material reality of local food production as a feature shared by both FSP and AFNs. From this perspective, FSP can be understood as a more radical variant of AFNs given its more substantial environmental and social impact (FSP is more widespread and socially inclusive and less dependent on market transactions). By uncovering the epistemological underpinnings of these different framings of FSP and exploring their implications for food practices on the ground, this article draws general lessons for scholarship aiming to advance food system transformation.
Multicenter evaluation of the IL‐3‐pSTAT5 assay to assess the potency of cryopreserved stem cells from cord blood units: The BEST Collaborative study
Authors: Trépanier Patrick , Fournier Diane , Simard Carl , Fontaine Magali J. , Stroncek David , Takanashi Minoko , McKenna David , Schwartz Joseph , Tanhehco Yvette C. , Reems Jo‐Anna , Torrents Silvia , Kogler Gesine , Liedtke Stefanie , Giroux Martin , Holovati Jelena L. , Louis Isabelle , Prasath Arun , Pineault Nicolas , Bazin Renée ,   The Biomedical Excellence for Safer Transfusion Collaborative
Published: June 2022

AbstractBackgroundThe IL‐3‐pSTAT5 assay, a new, rapid, and standardized flow‐cytometry‐based assay may compensate for several limitations of the colony‐forming unit (CFU) assay typically used for stem cell potency assessments of cord blood units (CBU). We performed an inter‐laboratory evaluation of the performance of this new assay.Study design and methodsThis Biomedical Excellence for Safer Transfusion (BEST) Collaborative multicenter, international study included 15 participants from public cord blood banks (CBBs), CBB‐supporting research laboratories, and stem cell laboratories. To perform the IL‐3‐pSTAT5 assay, participating centers received reagents, instructions, and 10 blind CBU samples, including eight normal samples and two samples exposed to a transient warming event. We measured inter‐laboratory agreement qualitatively (proportion of correctly classified samples) and quantitatively (coefficient of variation [CV], correlation coefficients, receiver operating characteristics (ROC) curve, and intraclass correlation coefficient [ICC]).ResultsThe qualitative agreement was 97.3% (i.e., 107/110; Fleiss' kappa = 0.835). The average CV on a per‐sample basis was 11.57% among all samples, 8.99% among normal samples, and on a per‐center basis was 9.42% among normal samples. In a correlation matrix that compared results across centers, the mean Pearson's correlation coefficient was 0.88 (standard deviation = 0.04). The ICC was 0.83 (95% confidence interval = 0.68–0.95). The area under the curve (AUC) from the ROC curve was 0.9974.DiscussionExcellent qualitative and quantitative agreement was exhibited across laboratories. The IL‐3‐pSTAT5 assay may therefore be implemented in flow cytometry laboratories to rapidly and reliably provide standardized measures of stem cell potency in CBUs.