bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interaction of polygenetic variants related to inflammation with carbohydrate and vitamin D intakes in middle-aged and older adults in a large hospital-based cohort
Authors: Park Sunmin , Kang Suna 
Published: May 2022

AbstractLow-grade subclinical inflammation is interrelated with metabolic diseases, and its susceptibility interacts with genetic and environmental factors. We aimed to examine genetic variants related to a high risk for inflammation using serum C-reactive protein (CRP) concentration, interactions among the genetic variants and the genetic variant interaction with dietary and lifestyle factors in adults. The participants were divided into case and control by serum CRP concentrations: ≥ 0·5 mg/dl (case; n 2018) and < 0·5 mg/dl (control; n 47 185). Genetic variants contributing to high inflammation risk were selected using GWAS after adjusting covariates to influence inflammation, and genetic variant–genetic variant interactions were identified by generalised multifactor dimensionality reduction analysis. Polygenetic-risk scores (PRS) were constructed from the selected genetic variants, and PRS–nutrient interactions for the high inflammation risk were determined. The PRS included CRP_rs1205, OASL_rs3213545, APOE_rs429358, HNF1A_rs1169286, APOC1_rs7256200 and SLC13A3_rs424697. The PRS was positively associated with serum CRP concentration by 2·0 times after adjusting for covariates. The PRS interacted with age: older participants with High-PRS had much higher serum CRP concentrations than those with Low-PRS. Intake of carbohydrates, MUFA and vitamin D exhibited an interaction with PRS for inflammation risk (P < 0·05). In participants with high-carbohydrate/low-fat diets and low vitamin D intakes, those with High-PRS had a higher risk of serum CRP concentrations than those with Low-PRS. In conclusion, the participants with inflammation-related PRS potentially worsened inflammation status, especially in diets with high carbohydrates, low fat (especially MUFA) and low vitamin D. These results can be applied to personalised nutrition to reduce inflammation risk.
Understanding costs and benefits of thermal plasticity for pest management: insights from the integration of laboratory, semi-field and field assessments of Ceratitis capitata (Diptera: Tephritidae)
Authors: Steyn Vernon M. , Mitchell Katherine A. , Nyamukondiwa Casper , Terblanche John S. 
Published: May 2022

AbstractThe relative costs and benefits of thermal acclimation for manipulating field performance of pest insects depend upon a number of factors including which traits are affected and how persistent any trait changes are in different environments. By assessing plastic trait responses of Ceratitis capitata (Mediterranean fruit fly) across three distinct operational environments (laboratory, semi-field, and field), we examined the influence of different thermal acclimation regimes (cool, intermediate [or handling control], and warm) on thermal tolerance traits (chill-coma recovery, heat-knockdown time, critical thermal minimum and critical thermal maximum) and flight performance (mark-release-recapture). Under laboratory conditions, thermal acclimation altered thermal limits in a relatively predictable manner and there was a generally positive effect across all traits assessed, although some traits responded more strongly. By contrast, dispersal-related performance yielded strongly contrasting results depending on the specific operational environment assessed. In semi-field conditions, warm- or cold-acclimated flies were recaptured more often than the control group at cooler ambient conditions suggesting an overall stimulatory influence of thermal variability on low-temperature dispersal. Under field conditions, a different pattern was identified: colder flies were recaptured more in warmer field conditions relative to other treatment groups. This study highlights the trait- and context-specific nature of how thermal acclimation influences traits of thermal performance and tolerance. Consequently, laboratory and semi-field assessments of dispersal may not provide results that extend into the field setting despite the apparent continuum of environmental complexity among them (laboratory < semi-field < field).
Second-Wave Women's Movements as Foreign Policy Actors: Assessing Canadian Feminist Interventions before 1995
Authors: Bashevkin Sylvia 
Published: May 2022

AbstractThis article addresses second-wave feminist interventions in Canadian foreign policy debate with reference to two analytic streams: (1) political science and international relations (IR) perspectives since the late 1990s that stress the formal decisional aims of advocacy and the role of transnational networks in pressuring reluctant governments and (2) sociological approaches that underline movements’ cultural as well as statist dimensions and the significance of their domestic political strategies. Examining engagement by the Voice of Women (VOW) in nuclear weapons debates and National Action Committee on the Status of Women (NAC) in free trade controversies confirms sociological expectations of campaigners’ varied claims and contributions and the importance of their political rootedness in Canada. Consistent with political science and IR arguments, the study finds NAC paid growing attention to international political opportunities in 1990 and following. The conclusion considers implications of the analysis and directions for future research.
On-farm agronomic performance and farmer preference of quality protein maize grown under conservation agriculture in Southern Africa: a case for Zimbabwe
Authors: Nyakurwa C. S. , Gasura E. , Mabasa S. , Rugare J. T. , Setimela P. S. 
Published: May 2022

AbstractMaize is the most important staple food crop in southern Africa with human consumption averaging 91 kg/capita/year. Most smallholder farmers and weaning children depend on maize for much of the daily food requirements and it is the largest contributor of dietary proteins. Despite the development of quality protein maize (QPM) with high tryptophan and lysine content, stunting and kwashiorkor remain high in southern Africa partly due to low adoption of QPM varieties. The objective of this study was to compare the agronomic performance and farmer preferences of new generation of QPM with non-QPM varieties under conservation agriculture on-farm conditions. Eight QPM and four non-QPM varieties were tested on on-farm trials in Zimbabwe during the 2014/15 and 2015/16 cropping seasons at five different locations. Significant differences were detected among the genotypes for the measured traits in the two seasons. Similarly, genotype plus genotype × environment interactions were significant for both seasons for grain yield. Three QPM varieties, SC527, SC535 and SC643, recorded the highest and stable yield. Four QPM varieties, SC643, SC535, SC527 and MQ623, and a non-QPM variety, PAN413, were ranked high among farmers for overall ear characteristics as their most preferred varieties. The high-yielding and stable QPM varieties are likely to be adopted by farmers in southern Africa.
Do Cross-Sectional Predictors Contain Systematic Information?
Authors: Engelberg Joseph , McLean R. David , Pontiff Jeffrey , Ringgenberg Matthew C. 
Published: May 2022

AbstractFirm-level variables that predict cross-sectional stock returns, such as price-to-earnings and short interest, are often averaged and used to predict market returns. Using various samples of cross-sectional predictors and accounting for the number of predictors and their interdependence, we find only weak evidence that cross-sectional predictors make good time-series predictors, especially out-of-sample. The results suggest that cross-sectional predictors do not generally contain systematic information.
A checklist of larval Digenea (Platyhelminthes: Trematoda) in molluscs from inland waters of Argentina: one hundred years of research
Authors: Merlo M.J. , Parietti M. , Fernández M.V. , Flores V. , Davies D. 
Published: May 2022

Abstract
A checklist of larval digeneans parasitising molluscs from inland waters of Argentina is presented here. Based on the bibliographical survey of 113 scientific articles and nine theses published between 1930 and 2021, 213 digeneans were found, which were distributed within 13 superfamilies and 35 families. The parasites were identified in 102 locations, encompassing eight of the sixteen biogeographical provinces in Argentina. Digeneans were found in 34 mollusc species (31 gastropods and three bivalves) belonging to 17 genera. The available data are presented for each digenean species, and included host information, localities, prevalence values, type of habitat, life cycle information (natural or experimental host), and information on material and genetic sequences deposited in repositories. Only 21.1% of individuals were identified to species level, and 8.5% to genus level. In addition, the genetic sequences of only 10 species (4.7%) were available at GenBank. This survey constitutes the first checklist of parasitic helminths in molluscs from inland waters of Argentina.
Multimorbidity Treatment Burden Questionnaire (MTBQ): Translation, Cultural Adaptation, and Validation in French-Canadian
Authors: Guénette Line , Turcotte Véronique , Bélanger Laurianne , Blais Lucie , Sirois Caroline , Lunghi Carlotta , Duncan Polly 
Published: May 2022

AbstractReliable treatment burden measures are needed given the aging population and the associated increase in multimorbidity and polypharmacy. Treatment burden is defined as the effort to care for one’s health and the resulting impact on one’s daily life. This study aimed to translate the Multimorbidity Treatment Burden Questionnaire (MTBQ) for French-Canadians and assess its reliability and validity. The MTBQ was translated and tested with cognitive debriefing interviews, and the French version (MTBQ-F) was then administered 2 times among 105 participants. Reliability and validity were examined using the intra-class correlation coefficient (ICC), Cronbach’s alpha, and Spearman’s correlations. The median global MTBQ-F scores were 32.69 (interquartile range [IQR]: 21.15-48.08) and 30.77 (IQR: 21.15-46.15) for the first and second administrations, respectively. Test-retest (ICC: 0.73; 95% CI: 0.63-0.81) and internal consistency reliability (Cronbach’s alpha: 0.80) were good. There was a moderate positive correlation between the MTBQ-F score and the number of self-reported conditions (rho: 0.28). This valid instrument could identify patients experiencing a high treatment burden and assess the impact of interventions among them.
Social, demographic and behavioural determinants of SARS-CoV-2 infection: a case-control study carried out during mass community testing of asymptomatic individuals in South Wales, December 2020
Authors: Thomas Daniel Rh. , Fina Laia Homar , Adamson James P. , Sawyer Clare , Jones Angela , Nnoaham Kelechi , Barrasa Alicia , Shankar A. Giri , Williams Chris J. 
Published: May 2022

Abstract
Between 21 November and 22 December 2020, a SARS-CoV-2 community testing pilot took place in the South Wales Valleys. We conducted a case-control study in adults taking part in the pilot using an anonymous online questionnaire. Social, demographic and behavioural factors were compared in people with a positive lateral flow test (cases) and a sample of negatives (controls). A total of 199 cases and 2621 controls completed a questionnaire (response rates: 27.1 and 37.6% respectively). Following adjustment, cases were more likely to work in the hospitality sector (aOR 3.39, 95% CI 1.43–8.03), social care (aOR 2.63, 1.22–5.67) or healthcare (aOR 2.31, 1.29–4.13), live with someone self-isolating due to contact with a case (aOR 3.07, 2.03–4.62), visit a pub (aOR 2.87, 1.11–7.37) and smoke or vape (aOR 1.54, 1.02–2.32). In this community, and at this point in the epidemic, reducing transmission from a household contact who is self-isolating would have the biggest public health impact (population-attributable fraction: 0.2). As restrictions on social mixing are relaxed, hospitality venues will become of greater public health importance, and those working in this sector should be adequately protected. Smoking or vaping may be an important modifiable risk factor.
The chromatic profile of locally colourable graphs
Authors: Illingworth Freddie 
Published: May 2022

AbstractThe classical Andrásfai-Erdős-Sós theorem considers the chromatic number of$K_{r + 1}$-free graphs with large minimum degree, and in the case,$r = 2$says that anyn-vertex triangle-free graph with minimum degree greater than$2/5 \cdot n$is bipartite. This began the study of the chromatic profile of triangle-free graphs: for eachk, what minimum degree guarantees that a triangle-free graph isk-colourable? The chromatic profile has been extensively studied and was finally determined by Brandt and Thomassé. Triangle-free graphs are exactly those in which each neighbourhood is one-colourable. As a natural variant, Luczak and Thomassé introduced the notion of a locally bipartite graph in which each neighbourhood is 2-colourable. Here we study the chromatic profile of the family of graphs in which every neighbourhood isb-colourable (locallyb-partite graphs) as well as the family where the common neighbourhood of everya-clique isb-colourable. Our results include the chromatic thresholds of these families (extending a result of Allen, Böttcher, Griffiths, Kohayakawa and Morris) as well as showing that everyn-vertex locallyb-partite graph with minimum degree greater than$(1 - 1/(b + 1/7)) \cdot n$is$(b + 1)$-colourable. Understanding these locally colourable graphs is crucial for extending the Andrásfai-Erdős-Sós theorem to non-complete graphs, which we develop elsewhere.
DISPERSAL OF HYDROGEN IN THE RETINA—A THREE-LAYER MODEL
Authors: MANSOOR W. F. , HOCKING G. C. , FARROW D. E. 
Published: May 2022

AbstractTwo simple mathematical models of advection and diffusion of hydrogen within the retina are discussed. The work is motivated by the hydrogen clearance technique, which is used to estimate blood flow in the retina. The first model assumes that the retina consists of three, well-mixed layers with different thickness, and the second is a two-dimensional model consisting of three regions that represent the layers in the retina. Diffusion between the layers and leakage through the outer edges are considered. Solutions to the governing equations are obtained by employing Fourier series and finite difference methods for the two models, respectively. The effect of important parameters on the hydrogen concentration is examined and discussed. The results contribute to understanding the dispersal of hydrogen in the retina and in particular the effect of flow in the vascular retina. It is shown that the predominant features of the process are captured by the simpler model.
Locating and Situating Justice Pal: TWAIL, International Criminal Tribunals, and Judicial Powers
Authors: XAVIER Sujith 
Published: May 2022

AbstractThis paper brings forward Justice Pal's dissenting opinion at the Tokyo Tribunal to add to Third World Approaches to International Law (TWAIL) literature on international criminal law and the rules of evidence and procedure. It is part of a TWAIL effort to scrutinize the everyday practices of international prosecutions through procedural and evidentiary rules. By locating and situating Justice Pal's reasoning within the broader academic literature on dissents in international criminal law, it is possible to illustrate how and why Justice Pal's views were obscured as a relevant dissent. From this vantage point, this paper pursues Justice Pal's legacy as it relates to the rules of evidence and procedure in the International Criminal Tribunal for the Former Yugoslavia and International Criminal Tribunal for Rwanda. It traces the evolution of the judicial power to draft and amend these rules, and examines the impact of these decisions on the everyday functions of the tribunals and how truth is determined.
Effect of differential levels of simulated overhead irrigation on residual herbicides applied to wheat straw–covered soil for barnyardgrass control
Authors: Sperry Benjamin P. , Ferguson J. Connor , Bond Jason A. , Kruger Greg R. , Johnson Ashli B. , Reynolds Daniel B. 
Published: May 2022

AbstractCrop residue can intercept and adsorb residual herbicides, leading to reduced efficacy. However, adsorption can sometimes be reversed by rainfall or irrigation. Greenhouse experiments were conducted to evaluate the effect of differential overhead irrigation level on barnyardgrass response to acetochlor, pyroxasulfone, and pendimethalin applied to bare soil or wheat straw–covered soil. Acetochlor applied to wheat straw–covered soil resulted in 25% to 40% reduced control, 30 to 50 more plants 213 cm−2, and greater biomass than bare soil applications, regardless of irrigation amount. Barnyardgrass suppression by pyroxasulfone applications to wheat straw–covered soil improved with increased irrigation; however, weed control levels similar to bare soil applications were not observed after any irrigation amount. Barnyardgrass densities from pyroxasulfone applications to bare soil decreased with irrigation but did not change in applications to wheat straw–covered soil. Aboveground barnyardgrass biomass from pyroxasulfone decreased with greater irrigation amounts in both bare soil and wheat straw–covered soil applications; however, decreased efficacy in wheat straw–covered soil applications was not alleviated with irrigation. Pendimethalin was the only herbicide tested that displayed reduced efficacy when irrigation amounts increased in applications to both bare soil and wheat straw–covered soil. Barnyardgrass control from pendimethalin applied to wheat straw–covered soil was similar to bare soil applications when approximately 0.3 to 1.2 cm of irrigation was applied; however, irrigation amounts greater than 1.2 cm resulted in greater barnyardgrass control in bare soil applications. No differences between wheat straw–covered soil and bare soil applications of pendimethalin were observed for barnyardgrass densities. These data indicate that increased irrigation or rainfall level can increase efficacy of acetochlor and pyroxasulfone. Optimal rainfall or irrigation amounts required for efficacy similar to bare soil applications are herbicide specific, and some herbicides, such as pendimethalin, may be adversely affected by increased rainfall or irrigation.
Tolerance of four dry bean market classes to flufenacet, acetochlor, and S-metolachlor applied preplant incorporated
Authors: Symington Hannah E. , Soltani Nader , Kaastra Allan C. , Hooker David C. , Robinson Darren E. , Sikkema Peter H. 
Published: May 2022

AbstractCommon bean and azuki bean are poor competitors with weeds and demonstrate sensitivity to herbicides used for weed control in soybean. S-metolachlor, flufenacet, and acetochlor are categorized as Group 15 herbicides and provide control of multiple annual grass and select small-seeded broadleaf weeds. By way of field trials near Exeter and Ridgetown, Ontario, in 2019, 2020, and 2021, four dry bean market classes (azuki, kidney, small red, and white bean) were evaluated for their tolerance to 1× established label rates and 2× rates of S-metolachlor (1,600 and 3,200 g ai ha−1), flufenacet (750 and 1,500 g ai ha−1) and acetochlor (1,700 and 3,400 g ai ha−1) applied preplant incorporated (PPI). Injury was evaluated by assessing visible injury symptoms, density, shoot biomass, height, seed moisture content, and seed yield. Azuki bean was more sensitive to the Group 15 herbicides than other dry bean market classes; the Group 15 herbicides caused a 12% reduction in azuki bean growth at 2 wk after emergence; growth reduction was ≤2% in the other bean classes. Flufenacet (2× rate) was the most injurious treatment, causing a 27% reduction in azuki bean yield. This study concludes that kidney, small red, and white bean have a sufficient margin of crop safety to flufenacet, acetochlor, and S-metolachlor applied PPI. Azuki bean was sensitive to flufenacet; additional research is needed to investigate azuki bean tolerance to acetochlor and S-metolachlor applied PPI.
Self-offloading therapeutic footwear using compliant snap-through arches
Authors: Maharana Priyabrata , Sonawane Jyoti , Belehalli Pavan , Ananthasuresh Gondi Kondaiah 
Published: May 2022

AbstractIn diabetic peripheral neuropathy, offloading high-plantar-pressure areas usingstatically offloadedcustomized insoles or expensive sensors and actuators are commonly-followed treatment procedures. In this article, we propose the concept ofdynamically self-offloadingtherapeutic footwear that operates mechanically without using sensors and actuators. We achieve this by using an array of snapping arches. When a load higher than a bespoke value is applied, these arches enter negative-stiffness regime and offload the high-pressure region by snapping to a different shape. They again return to their initial shape when the load disappears. Thus, they serve as both sensors and actuators that get actuated by person’s body weight. We present an analytical method to compute the switching load and the switchback time of such arches and use them to customize the footwear according to the person’s body weight, gait speed, and foot size. We identify the high-pressure regions from the clinical data and place the arches such that these high-pressure regions get dynamically offloaded, and the pressure gets redistributed to other regions. We considered 200 kPa as a limiting pressure to prevent the prolonged effects of high plantar pressure. To check the efficacy of the concept, a complete 3D-printed prototype made of thermoplastic polyurethane was tested and compared with barefoot and in-shoe plantar pressure for subjects recruited at a clinical facility. We notice that the self-offloading insole shows the plantar pressure reduction at all the foot regions, and significant offloading of 57% is observed at the forefoot region.
New Insights on the Radiative Impacts of Ozone‐Depleting Substances
Authors: Chiodo Gabriel , Polvani Lorenzo M. 
Published: May 2022

AbstractThe global warming potential of Ozone‐depleting substances (ODS) has long been known to be thousands of times larger than the one of CO2, but their climate impacts as greenhouse gases, i.e. unmediated by ozone depletion, has received relatively little attention. Focusing on the period 1955–2005, we here present results from offline radiative forcing (RF) calculations from a global chemistry climate model. Using realistic distributions of ODS and consistent stratospheric ozone, we show that ODS dominate the adjusted stratospheric warming of the lower stratosphere, where CO2 has little radiative impact. We also show that the global mean RF of stratospheric ozone only cancels a fraction of the RF of ODS, leaving an important ODS contribution to anthropogenic forcing. Finally we show that the RF of ODS opposes Arctic amplification, its equator‐to‐pole gradient being larger than the one of CO2.