bluuebunny/crossref_metadata_2025_split huggingface dataset:
Meningioma in shape
Authors: Cucu A.I. , Cosman Mihaela , Dobrovat B. , Dascalu Cristina , Jitaru Ioana , Sandu R.B. , Tudor A. , Costea Claudia , Turliuc Mihaela , Dumitrescu Gabriela , Sava Anca , Poeata I. 
Published: April 2022

Objective: The aim of this study was to evaluate the possible relationship between the appearance of tumour margins of atypical meningiomas and the risk of tumour recurrence, as well as progression-free survival. We also evaluated the correlations between the tumour margins and the neuroimaging characteristics (e.g. brain oedema and contrast enhancement) along with pathological features (e.g. brain invasion and mean value of Ki-67 LI).
Material and methods: In our study, we included 81 patients diagnosed with atypical meningioma (grade II meningioma), who have undergone surgery at the "Prof. Dr N. Oblu" Emergency Clinical Hospital Iasi, between January 1, 2010, and December 31, 2019. We followed the MRI imaging characteristics (e.g. tumour margins patterns, contrast enhancement, oedema grading and tumour volume), but also the pathological characteristics such as brain invasion and the mean value of the Ki-67 labelling index. The assessment of tumour recurrence was made using MRI imaging (T1+ contrast), over a follow-up period of 5 years after the surgery.
Results: In our study, we observed that 59.3% (n=48) of meningiomas had an irregular appearance. The irregular margins predominated in the male population (65.1%) and were statistically significantly correlated with brain oedema (p<0.001), contrast enhancement (p<0.01), anatomical location (p<0.014) and the mean value of the Ki-67 labelling index (p<0.01). The tumour margins were not correlated with brain invasion or volume of meningiomas.
Conclusion: In our series of patients we found that the irregular margin was not a prognostic factor for tumour recurrence over a period of 5 years or for progression-free survival.
A solitary case of gliosarcoma an indication for TP53 mutation analysis: a non-concordant finding
Authors: Abdulla Ebtesam , Hameed Nabeel , Arora Roopa 
Published: April 2022

Background: Li-Fraumeni syndrome (LFS) is a hereditary, autosomal dominant malignancy predisposition induced by a mutant TP53. Here, we describe a gliosarcoma (GS) case with a clinical family history impressive for an LFS case in the absence of inherited germline TP53 mutations.
Case description: We present a 44-year-old female with a right high parietal mass. The mass proved pathologically to be GS with an isocitrate dehydrogenase-1 (IDH1) mutation. Pedigree analysis identified five first-degree and second-degree relatives with LFS spectrum malignancies. The patient tested positive for TP53 mutation; however, her family tested negative.
Conclusion: Of all the tumours, GSs are the least described entity with LFS. We are highlighting the need to do a genetic survey in family members of the patient who has been diagnosed to have gliosarcoma and other tumours consistent with LFS.
Possibilities of endoscopic endonasal transsphenoidal surgery in treatment of growth-hormone pituitary adenomas
Authors: Aksyonov Ruslan V. , Palamar Orest I. , Huk Andriy P. , Teslenko Dmytro S. , Okonskyi Dmytro I. 
Published: April 2022

Pituitary adenomas are one of the most common primary central nervous system tumours and have an estimated prevalence of 17%. Management of hormone-secreting pituitary adenomas involves a multidisciplinary approach that can incorporate surgical, medical, and/or radiation therapies. Acromegaly is a rare, chronic disorder that mostly results from growth hormone (GH)-secreting pituitary adenoma. We analyzed the outcomes of surgical treatment for growth hormone (GH) pituitary adenomas based on 28 cases and determine factors that lead to biochemical remission.
Possible predictive markers in surgical decision making in patients with degenerative or isthmic lumbar spondylolisthesis
Authors: Yüksel Ulaş , Ogden Mustafa , Karagedik Mustafa Ilker , Kultur Turgut , Bakar Bulent 
Published: April 2022

Background: Although age, comorbidity, duration and severity of symptoms, slippage degree, and flexion-extension slipping stability during X-ray imaging are effective in making a surgical decision in patients with spondylolisthesis, these factors are rarely based on definitive evidence. The aim of this study was to determine the efficacy of clinical, radiological and biochemical findings in surgical decision making in these patients.
Materials and Methods: Patients’ data including age, gender, degree and type (i.e. degenerative or isthmic) of the spondylolisthesis, urinary incontinence, neurogenic claudication were recorded. Radiological imaging studies (lumbar dynamic X-ray, computed tomography, magnetic resonance imaging), serum glucose, C-reactive protein and erythrocyte sedimentation rate values of the patients obtained during hospital admissions were evaluated.
Results: Forty patients were followed conservatively and 12 patients were treated surgically. Degenerative spondylolisthesis was seen in 22 patients. Nine patients had neurogenic urinary incontinence and 19 patients had neurogenic claudication. When the patients were divided into two groups with and without surgical treatment, the presence of the pars defect, slipping distance in a neutral position and slipping distance in flexion position was significantly different between groups. A positive correlation was found between pars defect and surgical treatment. Likelihood ratio test results revealed that the presence of pars defect, neurogenic claudication and neurogenic urinary incontinence could be the best parameters in decision making the surgical treatment.
Conclusion: The presence of pars defect, neurogenic claudication and urinary incontinence could be the best parameters that may help the surgeon to make the surgical treatment decision.
Indirect revascularization in an Iraqi child with Moyamoya Disease
Authors: Hoz Samer S. , Al-Khafaji Aktham O. , Al-Sharshahi Zahraa F. , Alrawi Mohammed A. 
Published: April 2022

Background: Moyamoya disease (MMD) is a rare cerebrovascular disease characterized by bilateral stenosis starting at the supraclinoid internal carotid artery (ICA), with the development of a collateral network of vessels. It is an established cause of stroke in the pediatric age group. Despite its increasing prevalence in various parts of the world, it remains largely underrecognized in the Middle East, particularly in Iraq. This is the first case of MMD in an Iraqi patient undergoing surgery.
Case description: A 12-year-old boy presents with a 3-months history of progressive behavioural changes. MRI revealed diffuse infarcts of different ages. MRA and CT angiography revealed extensive asymmetrical steno-occlusive changes of the supraclinoid ICAs extending into the anterior and middle cerebral arteries, with the development of a collateral network in the basal ganglia. Indirect revascularization of the right side by encephaloduroarteriomyosynangiosis (EDAMS) was performed. The clinical status of the patient improved during the follow-up and the MRA showed a re-establishment of the blood flow to the MCA.
Conclusion: MMD should be recognized as a cause of stroke or recurrent TIAs in the Iraqi population, particularly in pediatric patients. EDAMS is an effective revascularization procedure with good results in pediatric patients.
Giant, primary, hydatid cyst of the gluteal region
Authors: Iacob G. , Rosiu R. , Luchian Mihaela , Simion G. 
Published: April 2022

Background: Primary hydatid disease in the muscle is extremely rare, resulting in either the spread of cysts spontaneously or after operations for hydatidosis in distant regions.
Methods: Report of an unusual case of primary hydatid cyst in the gluteus muscle, behaving as enlarging soft-tissue tumour, with a review of the literature.
Results: Magnetic resonance imaging revealed an intramuscular cyst in the gluteus muscle; and no cyst existed in any other location. The cyst was excised totally, and the diagnosis of muscular cystic hydatidosis was confirmed by histopathologic examination. In follow-up of two years after the operation, there has been no recurrence in either patient.
Conclusion: The involvement of the gluteus maximus muscle without the evidence of hepatic or pulmonary disease is rare, characterized by slow development, but a major local extension must be considered in the differential diagnosis of a cystic mass with well-defined margins in the extremities of individuals from endemic regions. Physical examination, serology results and radiological findings should be interpreted with care, especially in hydatid cyst endemic countries. Surgery is still the treatment of choice, with total cyst excision.
Important controversies in lumbar spine surgery: which patients benefit from lumbar spinal fusion and who should be fused?
Authors: Urian F. , Iacob G. , Ciurea A.V. 
Published: April 2022

Considering the rising tendency in the application of lumbar spine devices, a rigorous selection of candidates for lumbar spinal fusion must follow the benefit of the patient in terms of a better outcome than classical techniques or conservatory treatment. We pulled essential information from scientific sources regarding the clinical results of patients who underwent fusion surgery to sift patients who do better from fusion.
We found out that imagistic proof of instability such as spondylolisthesis associated with lumbar spinal stenosis and refractory pain takes the most from spinal fusion procedures. Oswestry disability index improvement along with restoring the function and reduction of pain remained the postoperative desires of a successful fusion. Clinical amelioration with bracing test prior to intervention was a predictor of better results after fusion. Exclusion criteria like psychiatric disorders and prior lumbar spine surgery were highlighted since studies demonstrated that they are bad predictors of outcome in spinal fusion surgery.
Laminectomy was nowhere implemented in the literature as to be urgently fused since only about 20% of patients manifest instability after this classical procedure. Iatrogenic segmental instability after laminectomy, radiologically proven should be a candidate for spinal fusion. These procedures have high costs and high rates of complications putting the patient’s functional status and quality of life at uncertainty since there is still a lot of debate in this area of spinal neurosurgery.
Ferrans and powers quality of life index for spinal cord injury
Authors: Divyalasya T.V.S , Kumar A. Kiran , Bhat N.R. Sahana , Jahnavi M. , Jena Ranjan Kumar , Lakhan Ram , Subrahmanyam B. V. , Agrawal Amit 
Published: April 2022

Objective: To translate and culturally adapt the Telugu version of Quality-of-Life tool among Spinal Cord Injury patients.
Method: It’s a prospective cross-sectional study conducted at a tertiary neuro centre care hospital. The English version was translated into Telugu by two expert medical professionals and cross-checked by three experts in Telugu vocabulary. Nursing students who had good proficiency in reading and writing in English and Telugu languages were chosen for checking tool reliability. Initially English language was administered on the satisfaction domain followed by the importance domain one month apart. After two months Telugu version was administered in the same way as the English version. The reliability analysis was done.
Results: The tool was administered to 50 nursing students. The Cronbach’s alpha for the satisfaction domain was 0.97 and the importance domain was 0.91, indicating excellent reliability.
Conclusion: The Telugu version of the QOL tool had excellent reliability. Therefore it can be administered in the Telugu language for evaluating the quality of life of people with spinal cord injury.
Investigation of COVID-19 vaccine hesitation in Turkey with YouTube analysis method
Authors: ALKAN Sevil , AKKAYA Bülent , ÖNTÜRK AKYÜZ Hatice 
Published: April 2022

Aim: Nowadays many people search the internet to gain health information including Coronavirus disease 2019 (COVID-19) vaccines. YouTube™ is one of the most widely used websites. However, the quality and accuracy of health-related YouTube™ videos are still controversial. In this study we aimed to research the COVID-19 vaccine hesitation in Turkey by using YouTube analyses method.
Material and Method: In this study, “COVID 19’’ OR “coronavirus’’ OR “SARSCOV 2’’ ‘and “vaccine’’ OR “vaccination’’ and “vaccine hesitancy’’ OR “vaccine hesitation’’ keywords were used to search videos on YouTube™. Firstly, non-Turkish videos and duplicate videos were excluded. Some details about videos such as duration (seconds), view count, number of comments, total likes/ dislikes were recorded. DISCERN (Quality Criteria for Consumer Health Information), JAMA (Journal of the American Medical Association) scores, and Video Power Index (VPI) values of the videos were calculated.
Results: Most of the videos were uploaded by news agencies (48%). DISCERN scores of the videos were ranged between very poor and good. The mean JAMA score was found 2.9 that is accepted as a high score. There was a statistically significant difference in the VPI and JAMA scores among videos’ sources (p < 0,05).
Conclusion: Vaccine hesitation can be reduced by increasing the quality of the video content prepared by academic and govermental organizations. The correct use of YouTube videos in community vaccination behaviors can play an important role in the spread of COVID 19 among the community and help control the pandemic.
Dissociative symptoms in generalized anxiety disorder and panic disorder and its relationship with temperament-character features
Authors: SEVİNDİK Muhammet , NAZLI Şerif Bora , KOÇAK Orhan Murat 
Published: April 2022

Introduction: The relationship between anxiety and dissociative symptoms is frequently mentioned, but dissociative symptoms are not seen in all patients with anxiety disorder. The aim of this study is to investigate the relationship between dissociative symptoms and temperament-character features in patients with anxiety disorders.
Methods: The study sample consisted of 75 patients diagnosed with generalized anxiety disorder (GAD) and panic disorder (PD) according to DSM-5 and 75 healthy individuals for the control group (HC). The severity of their complaints were assessed using Hamilton Anxiety and Depression Rating Scales (HAM-A, HAM-D). Sociodemographic data form, Dissociative Experiences Scale (DES), Dissociation Scale (DIS-Q) and Temperament-Character Inventory (TCI) were filled for every participant.
Results: There was a significant difference between the groups in terms of HAM-A, HAM-D, DES and DIS-Q scores (PD> GAD> HC). The factors affecting DES and DIS-Q scores were high HAM-A scores, diagnosis, low self-directedness(SD) and high self-transcendence(ST) scores, and when the diagnosis was checked, DES and DIS-Q scores continued to be affected by HAM-A, SD and ST scores.
Conclusion: The high prevalence of dissociative symptoms was confirmed in patients with anxiety disorder. It was observed that character traits of low SD and high ST may be predisposing for the development of dissociative symptoms, while temperament traits were not influential on dissociative symptoms. These results may suggest that dissociation is not only related to trauma.
De la caza de brujas al culto de brujas
Authors: Henningsen Gustav 
Published: April 2022

En 1984 Gustav Henningsen publicó un libro en danés titulado De la caza de brujas al culto de brujas. 1484-1984*, de gran impacto en los estudios internacionales sobre el fenómeno antropológico e histórico de la brujería. Lo abordaba en toda su dimensión espacial europea y densidad cronológica. La obra interesó mucho, como lo reflejan las numerosas reseñas elogiosas que recabó, si bien ha pasado desapercibido en España al haber sido publicado en danés en Copenhague. Gustav Henningsen mostraba en fecha temprana dos de sus cualidades como investigador: el acceso a las fuentes primarias documentales y su complementariedad con otros materiales igualmente valiosos, como los iconográficos. Esta obra recoge un capítulo [pp. 70-92] dedicado al gran proceso de Zugarramurdi, traduciendo siete...
Enciclopedia de la brujería
Authors: Henningsen Gustav 
Published: April 2022

Richard Golden coordinó la edición de una magna obra de referencia, la Encyclopedia of Witchcraft, que fue publicada en Santa Bárbara [Estados Unidos] en 2006. En ella participaron los especialistas más reputados a nivel mundial. Gustav Henningsen redactó ocho artículos temáticos*, de los que ofrecemos a continuación los cinco que están vinculados con la brujería vasco-navarra. Significativamente, él mismo es objeto de investigación por parte de William Monter (vol. 2, pp. 482-483) y es mencionado como autoridad en el artículo sobre historiografía de Wolfgang Behringer (vol. 2, p. 497). [P. de V.].
Kesesuaian computed tomography scan-base scoring system dengan hasil sitologi cairan pleura dalam membedakan efusi pleura maligna dan benigna
Authors: Arnawan Herdi , Latief Nikmatia , Ilyas Muhammad 
Published: April 2022

Abstract: The research aims at assessing the congruity CT scan-base scoring system according to Porcel and the pleural fluid cytology result in distinguishing the malignant from benign pleural effusions. The research used the diagnostic test by assessing the congruity CT scan-base scoring system according to Porcel with pleural fluid cytology result in distinguishing the malignant from benign pleural effusions through the Chi-square test and assessing the sensitivity and specificity of the pleural effusion score. The research result indicates that there are 71 samples with the pleural effusion undergoing the examinations of the chest MSCT scan and pleural fluid cytology in General Central Hospital dr. Wahidin Sudirohusodo, Makassar, from September 2019 to August 2020, in which there are 26 samples with the malignant pleural effusion and 45 samples with benign pleural effusion. There is significant correlation between CT scan-base scoring system according to Porcel and the pleural fluid cytology result, in which the score < 7 indicates the benign pleural effusion, while the score ≥ 7 indicates the malignant pleural effusion, with the sensitivity of 88.4% (73.1 – 88.5 %) and specificity of 75.5% (73.1 – 88.5 %). The positive predictive value 67.6%, negative predictive value is 91.8%.Keywords: pleural effusion; malignant pleural effusion; CT scan-base scoring system; pleural metastasisAbstrak: Penelitian ini bertujuan untuk menilai kesesuaian CT scan-base scoring system menurut Porcel dengan hasil sitologi cairan pleura dalam membedakan efusi pleura maligna dan benigna. Penelitian ini merupakan uji diagnostic, dengan menilai kesesuaian CT scan base scoring system menurut Porcel dengan hasil sitology cairan pleura dalam membedakan EPM dan EPB melalui Chi Sqaretest serta menilai sensitivitas dan spesifisitas dari skor efusi pleura. Hasil penelitian menunjukan terdapat 71 sampel dengan efusi pleura yang menjalani pemeriksaan MSCT-scan thorax dan sitology cairan pleura di RSUP dr. Wahidin Sudirohusodo, Makassar, periode September 2019 sampai Agustus 2020 yang masuk dalam penelitian kami, dimana terdapat 26 sampel EPM dan 45 sampel EPB. Terdapat hubungan bermakna antara CT scan base scoring system menurut Porcel dengan hasil sitology cairan pleura, dengan skor < 7, yang menunjukan EPB, sedangkan skor ≥ 7 yang menunjukan EPM, dengan sensitivitas 88.4% (73.1 – 88.5 %) dan spesifisitas 75.5% (73.1 – 88.5 %); nilai prediksi positif 67.6%; nilai prediksi negatif 91.8%.Kata kunci: efusi pleura; efusi pleura maligna; CT scan base scoring system; metastasis pleura.
Obesitas sebagai Faktor Risiko Rheumatoid Arthritis
Authors: Maniking Velania R. O. , Angmalisang Elvin C. , Wongkar Djon 
Published: April 2022

Abstract: Obesity is excess fat in the body, which clinically has a relationship with body mass index (BMI) which is thought to be a risk factor for several musculoskeletal disorders such as rheumatoid arthritis (RA). The aim of this study is to determine obesity as a risk factor of RA. The study was conducted using a literature review method and the literature was taken from 1 database, Pubmed. The keywords used were Body Mass Index AND Obesity AND Rheumatoid Arthritis. The article search used the PICOS framework, and obtained 12 literatures. For the result, obesity as a significant risk factor for the development of RA. In Conclusion: In the study, it was found that obesity can be a risk of RA. Keywords: Body Mass Index; Obesity; Rheumatoid ArthritisAbstrak: Obesitas merupakan kelebihan lemak pada tubuh, yang secara klinis memiliki hubungan dengan indeks massa tubuh (IMT) yang diperkirakan dapat menjadi salah satu faktor risiko pada beberapa gangguan muskuloskeletal seperti rheumatoid arthritis (RA). Penelitian ini bertujuan untuk mengetahui obesitas sebagai salah satu faktor risiko RA. Penelitian ini menggunakan metode literature review yang diambil dari 1 database, Pubmed. Kata kunci yang digunakan adalah Body Mass Index AND Obesity AND Rheumatoid Arthritis. Pencarian artikel digunakan PICOS framework dan didapatkan 12 literatur. Hasil yang didapatkan obesitas merupakan salah satu faktor risiko yang signifikan terjadinya perkembangan RA. Sebagai simpulan, penelitian ini menunjukkan bahwa obesitas dapat menjadi salah satu faktor risiko RA.Kata kunci: Indeks Massa Tubuh; Obesitas; Rheumatoid Arthritis