bluuebunny/crossref_metadata_2025_split huggingface dataset:
Visual and Auditory Complications during Deferasirox Therapy in Beta-thalassemia
Authors: Poosheshdoost Parastoo , Faraji Niloofar , Zeinali Tahereh , Baghersalimi Adel , Miremarati Aye , Darbandi Bahram 
Published: October 2022

Background: Deferasirox is an oral iron chelator widely used to treat iron overload in patients with transfusion-dependent β-thalassemia. This study investigated the prevalence of visual and auditory complications caused by deferasirox.
Materials and Methods: This cross-sectional study included 156 patients aged less than 18 years with transfusion-dependent β-thalassemia and deferasirox iron chelator consumption admitted to the 17 Shahrivar Hospital and the Besat Clinic in Rasht, Iran. All the patients were examined for visual and auditory complications caused by deferasirox in 2019. A checklist of the patients' demographical and clinical data was recorded. Data analysis was done with SPSS and reported by descriptive statistics. Then, Fisher's exact test was performed to examine the association between visual and auditory disorders and the use of deferasirox in terms of disease-related variables including age, sex, age of onset of using chelator, drug use duration, drug dosage, and mean 6-months serum ferritin levels (P <0.05 as the significance level).
Results: Of a total of 156 patients, 103 (66%) were female and 56 (35.9%) were 20-30 years of age. The prevalence of visual acuity change was 0.6%, and the prevalence of sensorineural hearing loss was 1.3%. There was only one female with the visual disorder decreasing to 9/10 and with a dose of 31-40 mg/kg/day with an average of 1000-2500 ng/ml six-month ferritin. Also, two females with hearing impairment were confirmed with a dose of ≤30 mg/kg/day, and an average of ≤1000 ng/ml six-month ferritin. The Fisher's exact test results showed no significant relationship between visual and auditory disorders with the use of deferasirox in terms of disease-related variables (p>0.05).
Conclusion: The study's findings showed no significant relationship between visual and auditory disorders with deferasirox consumption. The results indicated the safety of deferasirox regarding visual and auditory side effects. More studies are required to confirm the findings.
Late frost protection – what to retain from the Champagne experience?
Authors: Pauthier Basile , Debuisson Sébastien , Descôtes Arnaud 
Published: October 2022

With the occurrence of frost, sensitive plants are susceptible to damage. One of the most counter-intuitive impacts of climate change is the increasing frequency of spring frost. Studies have warned of this problem (Inouye, 2008), describing an earlier budburst due to higher temperatures during winter and the last day of frost remaining around the same date. The risk of polar jet stream destabilisation by quick warming has also been mentioned (Molitor et al., 2014). Since 2016, Western European vineyards have suffered from frost damage almost every year (Rochard et al., 2019).
Contribution of KH. MA. Sahal Mahfudh to Community Economic Empowerment
Authors: Prasetyoningrum Ari Kristin , Darojat Muhammad Irhas 
Published: October 2022

This article aims to analyze the contribution of KH. MA. Sahal Mahfudh in empowering the economy of the community which is motivated by conditions of unresolved poverty. This article is a library research using a sociological-historical approach. Data collection methods in this study using documentation and interviews. The analysis of this research uses qualitative analysis. The results of this study indicate that the contribution of KH. MA. Sahal Mahfudh in community economic empowerment can be a solution to poverty problems. The Islamic boarding school led by Kiai Sahal has become the driving force for the economic empowerment program for the surrounding community by developing various business units. The business units established by Kiai Sahal include: BPR Artha Huda with conventional systems, BPR Artha Mas Abadi using the sharia system, printing businesses (Masda Grafika and Masda Digital Printing), Rambutan Gardens, and Walet Enterprises.
The Concept of Advertisement: An Islamic Perceptive
Authors: Begum Azeema 
Published: October 2022

There is a general perception regarding advertisement that advertising has a strong influence on consumer behavior. Advertisement has an imperative role in changing the social and cultural values of society. For convincing and getting consumer’s attention, advertising is considered the most successful and influential way of transforming information regarding new products. The paper argues the concept of advertisement in the light of Islamic Sharia’h. We have found no evidence of any restriction for using advertisement as a promotional tool for products however; Islam has defined a certain set of laws that should be considered while making advertisements. Moreover, this paper also highlights some unethical issues of contemporary advertisement which are prohibited in Islam.
Shared Interoperable Clinical Decision Support Service for Drug-Allergy Interaction Checks: Implementation Study
Authors: Jung Sungwon , Bae Sungchul , Seong Donghyeong , Oh Ock Hee , Kim Yoomi , Yi Byoung-Kee 
Published: October 2022

Background
Clinical decision support (CDS) can improve health care with respect to the quality of care, patient safety, efficiency, and effectiveness. Establishing a CDS system in a health care setting remains a challenge. A few hospitals have used self-developed in-house CDS systems or commercial CDS solutions. Since these in-house CDS systems tend to be tightly coupled with a specific electronic health record system, the functionality and knowledge base are not easily shareable. A shared interoperable CDS system facilitates the sharing of the knowledge base and extension of CDS services.

Objective
The study focuses on developing and deploying the national CDS service for the drug-allergy interaction (DAI) check for health care providers in Korea that need to introduce the service but lack the budget and expertise.

Methods
To provide the shared interoperable CDS service, we designed and implemented the system based on the CDS Hooks specification and Health Level Seven (HL7) Fast Healthcare Interoperability Resources (FHIR) standard. The study describes the CDS development process. The system development went through requirement analysis, design, implementation, and deployment. In particular, the concept architecture was designed based on the CDS Hooks structure. The MedicationRequest and AllergyIntolerance resources were profiled to exchange data using the FHIR standard. The discovery and DAI check application programming interfaces and rule engine were developed.

Results
The CDS service was deployed on G-Cloud, a government cloud service. In March 2021, the CDS service was launched, and 67 health care providers participated in the CDS service. The health care providers participated in the service with 1,008,357 DAI checks for 114,694 patients, of which 33,054 (3.32%) cases resulted in a “warning.”

Conclusions
Korea’s Ministry of Health and Welfare has been trying to build an HL7 FHIR-based ecosystem in Korea. As one of these efforts, the CDS service initiative has been conducted. To promote the rapid adoption of the HL7 FHIR standard, it is necessary to accelerate practical service development and to appeal to policy makers regarding the benefits of FHIR standardization. With the development of various case-specific implementation guides using the Korea Core implementation guide, the FHIR standards will be distributed nationwide, and more shared interoperable health care services will be introduced in Korea.
Funding Philanthropy for PAUD Wadas Kelir Purwokerto
Authors: Nugroho Bayu Santo , Faozan Akhmad , Samiaji Mukhamad Hamid 
Published: October 2022

Research on philanthropy for financing educational institutions aims to find out about how the philanthropy of financing is carried out at PAUD Wadas Kelir Purwokerto. This research is included in qualitative descriptive research with a case study method. Data collection techniques were obtained through observation (researchers went directly to the PAUD Wadas Kelir institution), interviews (to principals and parents) and documentation (learning activities, activity programs, school financing sources). The results of this study show that the philanthropy of financing educational institutions in PAUD Wadas Kelir carried out by the community also supports learning activities so that the PAUD Wadas Kelir institutions have survived until now. The existence of this institutional financing philanthropy is very helpful in improving the quality of learning, completing school facilities, and improving the quality of early childhood education.
Transformation of sequential Fortran programs for their parallelization into hybrid clusters in the SAPFOR
Authors: Колганов А.С. , Гусев Г.Д. 
Published: October 2022

Процесс распараллеливания программ может быть затруднён ввиду их оптимизации под последовательное выполнение. Из-за этого полученная параллельная версия может быть неэффективной, а в некоторых случаях распараллеливание оказывается невозможным. Решить указанные проблемы помогают преобразования исходного кода программ. В данной статье рассматривается реализации в системе автоматизированного распараллеливания SAPFOR (System FOR Automated Parallelization) преобразований последовательных Фортран-программ, позволяющих облегчить работу пользователя в системе и существенно снизить трудоемкость распараллеливания программ. Применение реализованных преобразований в системе SAPFOR продемонстрировано на прикладной программе, решающей систему нелинейных дифференциальных уравнений в частных производных. Также было произведено сравнение производительности полученной параллельной версией с версиями, распараллелеными вручную с использованием DVM и MPI технологий.
The process of parallelizing programs can be difficult due to their optimization for sequential execution. Because of this, the resulting parallel version may be inefficient, and in some cases parallelization is not possible. Transformations of the source code of programs help to solve these problems. This article discusses the implementation of transformations of sequential Fortran programs in the SAPFOR (System FOR Automated Parallelization) system, which make it possible to facilitate the user's work in the system and significantly reduce the complexity of program parallelization. The application of the implemented transformations in the SAPFOR system is demonstrated on a program that solves a system of non-linear partial differential equations. The performance of the obtained parallel version was also compared with the versions parallelized manually using DVM and MPI technologies.
Gambaran Kualitas Pembelajaran Daring, Pelayanan Akademik, dan Tingkat Kepuasan Mahasiswa di Masa Pandemi COVID-19
Authors: Agustia Dita , Hakim Abdul Aziz , Sholikhah Anindya Mar’atus , Dewi Ratna Candra , Rimawati Nanda 
Published: October 2022

This research aims to evaluate the online lecture process during the pandemic period, as well as measure the level of student satisfaction towards the implementation of online lectures at the Faculty of Sports Science, Universitas Negeri Surabaya. This research was descriptive study with a survey research model. Sample withdrawal was done by purposive sampling method, which determines the class of 2017- 2020 as a research respondent. The student assessment and satisfaction questionnaire were measured using the Likert scale with alternative answers 1 (dissatisfied) to 4 (very satisfied). The data was descriptively analyzed and bivariate using independent t-test and Anova one way tests. A total of 50.5% of students have a good internet conditions. Lack of concentration is the most common problem (28.1%). The next problem is more lectures give students many assignments (17.6%). Overall, students' assessment of the online lecture process during the COVID 19 pandemic was good, While the level of student satisfaction with online lectures in the faculty of sports science is in the satisfied category. This result will be evaluated for lecturers and education personnel to continuously improve the quality of service to students.
External quality assessment of SARS-CoV-2 serology in European expert laboratories, April 2021
Authors: Mögling Ramona , Colavita Francesca , Reimerink Johan , Melidou Angeliki , Leitmeyer Katrin , Keramarou Maria , Lapa Daniele , Francalancia Massimo , Murk Jean-Luc , Vossen Ann , Carletti Fabrizio , Hogema Boris , Meijer Adam , Deprez Liesbet , di Caro Antonino , Castilletti Concetta , Reusken Chantal BEM 
Published: October 2022

Background
Countries worldwide are focusing to mitigate the ongoing SARS-CoV-2 pandemic by employing public health measures. Laboratories have a key role in the control of SARS-CoV-2 transmission. Serology for SARS-CoV-2 is of critical importance to support diagnosis, define the epidemiological framework and evaluate immune responses to natural infection and vaccine administration.

Aim
The aim of this study was the assessment of the actual capability among laboratories involved in sero-epidemiological studies on COVID-19 in EU/EEA and EU enlargement countries to detect SARS-CoV-2 antibodies through an external quality assessment (EQA) based on proficiency testing.

Methods
The EQA panels were composed of eight different, pooled human serum samples (all collected in 2020 before the vaccine roll-out), addressing sensitivity and specificity of detection. The panels and two EU human SARS-CoV-2 serological standards were sent to 56 laboratories in 30 countries.

Results
The overall performance of laboratories within this EQA indicated a robust ability to establish past SARS-CoV-2 infections via detection of anti-SARS-CoV-2 antibodies, with 53 of 55 laboratories using at least one test that characterised all EQA samples correctly. IgM-specific test methods provided most incorrect sample characterisations (24/208), while test methods detecting total immunoglobulin (0/119) and neutralising antibodies (2/230) performed the best. The semiquantitative assays used by the EQA participants also showed a robust performance in relation to the standards.

Conclusion
Our EQA showed a high capability across European reference laboratories for reliable diagnostics for SARS-CoV-2 antibody responses. Serological tests that provide robust and reliable detection of anti-SARS-CoV-2 antibodies are available.
Public health measures during the COVID-19 pandemic through the lens of community organisations and networks in the Netherlands (2020–2021): five lessons for pandemic decision-making
Authors: Kolner Carla , van der Borg Wieke , Sanders Jet , Keijsers Jolanda , Joosten Maysa , de Bruin Marijn 
Published: October 2022

Background
During the coronavirus disease (COVID-19) pandemic, key persons who were formally or informally active in community organisations and networks, such as sports clubs or cultural, educational, day care and healthcare facilities, occupied a key position between governments and citizens. However, their experiences, the dilemmas they faced and the solutions they generated when implementing COVID-19 measures in their respective settings are understudied.

Aim
We aimed to understand how key persons in different community organisations and networks experienced and responded to the COVID-19 measures in the Netherlands.

Methods
Between October 2020 and December 2021, the Corona Behavioural Unit at the Dutch national public health institute, conducted qualitative research based on narratives derived from 65 in-depth interviews with 95 key persons from 32 organisations and networks in eight different sectors.

Results
Firstly, key persons enhanced adherence and supported the resilience and well-being of people involved in their settings. Secondly, adherence was negatively affected where COVID-19 measures conflicted with important organisational goals and values. Thirdly, small changes and ambiguities in COVID-19 policy had substantial consequences, depending on the context. Fourthly, problem-solving was achieved through trial-and-error, peer support, co-creation and transparent communication. Lastly, the COVID-19 pandemic and measures highlighted inequalities in access to resources.

Conclusion
Pandemic preparedness requires organisational and community preparedness and a multidisciplinary public health approach. Structural engagement of governments with key persons in community organisations and networks is key to enhance public trust and adherence to pandemic measures and contributes to health equity and the well-being of the people involved.
KIAT-KIAT MENGEMBANGKAN PERILAKU BAIK (AKHLAKUL KARIMAH) PADA ANAK USIA DINI
Authors: Kuswanto Cahniyo Wijaya , Nabela Ulfa , Uminar Ajeng Ninda , Muslih Ahmad 
Published: October 2022

Abstrak
Gaya hidup, kebiasaan tawuran, atau prilaku tidak baik memberikan bukti bahwa prilaku baik (akhlakul karimah) penting diberikan sejak dini. Dengan menerapkan akhlakul karimah sejak dini kekacauan prilaku dapat teratasi. Penelitian ini bertujuan untuk mengetahui proses guru dalam mengembangkan perilaku baik (akhlakul karimah) pada anak usia dini. Penelitian menggunakan metode kualitatif dengan pengambilan data menggunakan observasi, dokumentasi dan wawancara. Hasil penelitian lapangan guru mengembangkan akhlakul karimah yaitu:1) pembiasaan rutin berdoa sebelum dan sesudah kegiatan 2) pembiasaan spontan sopan dan santun dalam perilaku sehari-hari, 3) Keteladanan yang baik hormat menghormati dengan orang lain, 4) membimbing anak mampu bersikap hormat pada orangtua maupun sesama. Temuan tersebut dapat diterapkan di sekolah maupun lingkungan keluarga guna mengembangkan perilaku baik (akhlakul karimah) bagi anak usia dini.
Kata Kunci: kiat-kiat, akhlakul karimah, anak usia dini
STIMULASI PENGEMBANGAN MOTORIK KASAR ANAK USIA DINI MELALUI PERMAINAN PAPAN TITIAN
Authors: Kurniati Arni , Sopiah Sopiah 
Published: October 2022

Abstrak
Pendidikan anak usia dini yaitu suatu upaya pemberian rangsang dalam membantu perkembangan jasmani dan rohani supaya memiliki kesiapan pada tingkat pendidikan dasar. Pemberian rangsang tersebut diantaranya meliputi aspek motorik, kognitif, bahasa, nilai agama moral, seni, dan sosial emosional. Enam aspek tersebut saling berkaitan, dengan demikian pendidikan yang diberikan harus bersifat menyenangkan supaya anak dapat berkembang sesuai tahapan usianya.
Peneliti melakukan pengamatan langsung di salah satu Lembaga TK ABA Landungsari Pekalongan khususnya kelompok B2, TK tersebut terletak di jalan HOS Cokroaminoto gang 13 Landungsari Pekalongan. Sekolah ini merupakan salah satu sekolah yang memiliki prestasi yang cukup baik dan memiliki program pengembangan motorik kasar.
Berdasarkan observasi peneliti di kelompok B 2 TK ABA Landungsari Pekalongan ditemukan hasil observasi yaitu dari 18 peserta didik, hanya di temukan 3 peserta didik saja yang sudah mampu berdiri di atas satu kaki dengan kedua tangan merentang tanpa bergoyang dan tanpa saling memegang temannya dengan menggunakan waktu sepuluh hitungan.
Selain observasi, peneliti juga melakukan wawancara, berdasarkan hasil wawancara peneliti dengan kepala sekolah ditemukan program pengembengan motorik kasar diantaranya, dengan permainan papan titian, engklek, lompat tali dan senam yang dilaksanakan pendidik untuk membangkitkan semangat anak sebelum belajar, sehingga pengembangan tersebut mampu menguatkan otot-otot besar anak.

Kata Kunci: Pendidikan anak usia dini, Pengembangan motorik kasar anak, Permainan papan titian
MUSIK TRADISIONAL BAGI PERKEMBANGAN KOGNITIF ANAK USIA DINI
Authors: Perdana Firdaus 
Published: October 2022

This study discusses the music traditional for early childhood to cognitive development. Through music education of children can develop a variety of cognitive abilities, especially in the cognitive development. Based on some of theories cognitive ability in early childhood in a musical activity able to develop well because of the music, children will be interested to learn. Music is important to someone, especially children who are still happy to move freely and play. Based on the theory that music will help explain the cognitive development of children. Fact music can give a good impact on the brain development of infants and children if he hears music playing softly, rhythmically quiet and not loud.
Pemahaman Konsep Matematis Dilihat dari Minat Belajar dengan Strategi Pembelajaran Genius Learning Berbantu Lagu Edukasi
Authors: Anathiya Ladika , Netriwati Netriwati , Andriani Siska 
Published: October 2022

Tujuan dalam penelitian ini adalah untuk mengetahui Pengaruh Strategi Pembelajaran Genius Learning berbantu Lagu Edukasi terhadap pemahaman konsep matematis , untuk mengetahui pengaruh antara peserta didik yang memiliki minat belajar tinggi, sedang dan redah terhadap pemahaman konsep matematis. Metode yang digunakan dalam penelitian adalah kuantitatif dengan jenis True Eksperiment Design. Populasi penelitian merupakan seluruh peserta didik kelas VII SMP Negeri 1 Sukau, teknik pengambilan sampel dalam penelitian ini menggunakan teknik Random sampling dimana kelas VII A sebagai kelas eksperimen 1 dengan menerapkan strategi pembelajaran Genius Learning berbantu lagu edukasi, kelas VII C sebagai kelas eksperimen 2 dengan menerapkan strategi pembelajaran Genius Learning dan kelas VII B sebagai kelas kontrol yang menggunakan metode konvensional. Instrumen yang digunakan untuk mengumpulkan data adalah tes pemahaman konsep matemats dan angket minat belajar. Teknik analisis data yang digunakan dalam penelitian ini yaitu uji Anova dua jalan dengan sel tak sama. Berdasarkan hasil uji, untuk hipotesis pertama ditolak karena nilai strategi pembelajaran Genius Learning berbantu Lagu Edukasi= 0,000 kurang dari. Kesimpulannya bahwa terdapat pengaruh strategi pembelajaran Genius Learning berbantu Lagu Edukasi terhadap kemampuan pemahaman konsep matematis peserta didik.
Pengaruh Gaya Belajar Siswa dan Pola Asuh Anak dalam Keluarga terhadap Hasil Belajar Matematika Siswa Kelas XI di SMA Islam YMI Wonopringgo Kabupaten Pekalongan
Authors: Albar Ardian Shafry , Pramesti Santika Lya Diah 
Published: October 2022

Hasil belajar adalah sebuah pencapaian yang dihasilkan siswa melalui suatu proses pembelajaran. Hasil belajar bisa dipengaruhi beberapa faktor yaitu gaya belajar siswa dan pola asuhnya didalam keluarga. Tujuan penelitian ini adalah mengetahui seberapa besar gaya belajar dan pola asuh siswa mempengaruhi hasil belajar matematika siswa di SMA Islam YMI Wonopringgo Kabupaten pekalongan. Penelitian ini merupakan penelitian kuantitatif. Pengumpulan data menggunakan metode angket dan dokumentasi. Teknik analisis data menggunakan analisis regresi linier berganda. Dari hasil uji penelitian didapatkan koefisien determinasi R2 variabel gaya belajar siswa berpengaruh terhadap hasil belajar siswa sebesar 29,1%. Kemudian hasil uji koefisien determinasi R2 variabel pola asuh anak dalam keluarga berpengaruh terhadap hasil belajar siswa sebesar 19,4%. Serta hasil uji koefisien determinasi R2 variabel gaya belajar siswa dan pola asuh anak dalam keluarga berpengaruh terhadap hasil belajar siswa sebesar 32,7%.