bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hutchinson-Gilford progeria syndrome complicated with stroke: A report of 2 cases and literature review
Authors: Wang Jingjing , Yu Qinmei , Ma Xiaohui , Yuan Zhefeng , Mao Jianhua 
Published: November 2022

BackgroundHutchinson–Gilford Progeria Syndrome (HGPS) is a ultrarare, fatal autosomal dominant disorder. The pathogenesis of the disease is a mutation in LMNA, which leads to the accumulation of progerin in cells, impairing the normal physiological functions. Stroke and transient ischemic attack seriously affect the survival rate and quality of life of HGPS children, although the literature of this aspect is limited. This study summarizes the clinical manifestations and related imaging features of HGPS children with stroke to improve pediatric clinicians' understanding of this disease.Case presentationBoth children have a de novo heterozygous mutation of LMNA [c.1824C &gt; T ( p.G608G)]. Case 1. At the age of 4 years, the child had a cerebral infarction, which manifested as blurred vision and communication disturbance. Multiple abnormal signals were observed on the head MRI in the bilateral frontoparietal cortex, bilateral semiovale center, lateral ventricle, and deep frontal and parietal lobes. Multiple abnormal white matter signals on head MRA: bilateral internal carotid artery stenosis with basilar artery, and bilateral thickening of the posterior communicating artery. Case 2. At the age of 8.5 years, the child presented with cerebral infarction, which manifested as decreased muscle strength and choking after drinking water. MRI of the head showed that the bilateral frontal lobes were small with multiple abnormal signal shadows in the bilateral center of the semiovale and the lateral ventricle. Brain MRA revealed that the bilateral internal carotid arteries (C5–7) were narrow and uneven in thickness, and the A1 segment of the left anterior cerebral artery was narrower than the contralateral one. After symptomatic and supportive treatment, the two children improved.ConclusionHemiplegia and physical weakness are the most prevalent stroke symptoms in children with HGPS, followed by headache, epilepsy, dysarthria, and psychosis as the primary manifestation in some children. Stroke in children with HGPS is mostly ischemic cerebral infarction caused by an insufficient cerebral blood supply. Pediatric cerebral infarction mainly occurs in the large vascular area, involving all vascular areas, with the internal carotid artery and middle cerebral artery being the most commonly accumulated.
Drug-induced fall risk in older patients: A pharmacovigilance study of FDA adverse event reporting system database
Authors: Zhou Shuang , Jia Boying , Kong Jiahe , Zhang Xiaolin , Lei Lili , Tao Zhenhui , Ma Lingyue , Xiang Qian , Zhou Ying , Cui Yimin 
Published: November 2022

Objectives: As fall events and injuries have become a growing public health problem in older patients and the causes of falls are complex, there is an emerging need to identify the risk of drug-induced falls.Methods: To mine and analyze the risk signals of drug-induced falls in older patients to provide evidence for drug safety. The FDA Adverse Event Reporting System was used to collect drug-induced fall events among older patients. Disproportionality analyses of odds ratio (ROR) and proportional reported ratio were performed to detect the adverse effects signal.Results: A total of 208,849 reports (34,840 fall events and 1,898 drugs) were considered. The average age of the included patients was 76.95 ± 7.60 years, and there were more females (64.47%) than males. A total of 258 drugs with positive signals were detected to be associated with drug-induced fall incidence in older patients. The neurological drugs (104, 44.1%) with the largest number of positive detected signals mainly included antipsychotics, antidepressants, antiparkinsonian drugs, central nervous system drugs, anticonvulsants and hypnotic sedatives. Other systems mainly included the circulatory system (25, 10.6%), digestive system (15, 6.4%), and motor system (12, 5.1%).Conclusion: Many drugs were associated with a high risk of falls in older patients. The drug is one of the critical and preventable factors for fall control, and the risk level of drug-induced falls should be considered to optimize drug therapy in clinical practice.
2.76–3.98 μm picosecond mid-infrared optical parametric generation in a muti-grating MgO: PPLN
Authors: Li Bowen , Yin Jinde , Wang Jintao , Yang Junbo , Yan Peiguang 
Published: November 2022

The high repetition rate, widely tunable, picosecond mid-infrared laser plays an important role in various fields. In this paper, the single-pass optical parametric generator (OPG) pumped by Yb-fiber laser based on MgO: PPLN is proposed. The Yb-fiber laser is mode locked by a nonlinear amplifying loop mirror (NALM) with an all-polarization-maintaining (PM) structure. A maximum power of 6.2 W was obtained with a repetition rate of 15.8 MHz and pulse duration of 18 ps after amplification by cascaded fiber. Based on the principle of nonlinear frequency down-conversion, the tunable mid-infrared output wavelength of 2.76–3.98 μm was realized by varying the crystal grating periods and temperature. The maximum power was 500 mW at 3.22 μm, corresponding to a quantum conversion efficiency of 25%, and the relative power fluctuation was measured as 0.37% over 30 min.
Employee innovative behavior and workplace wellbeing: Leader support for innovation and coworker ostracism as mediators
Authors: Wang Hui , Chen Xueshuang , Wang Hui , Xie Mingxing 
Published: November 2022

IntroductionMost previous studies focused on the antecedents of employee innovative behavior but rarely examined the outcomes of employee innovative behavior. Moreover, previous studies ignored the relationship between employee innovative behavior and workplace wellbeing. Based on social comparison theory and social exchange theory, this study introduces coworker ostracism and leader support for innovation as mediating variables to explore the “double–edged sword” effect of employee innovative behavior on workplace wellbeing.MethodsBased on a sample of 319 employees from Chinese companies, this study used SPSS 26.0 and MPLUS 8.3 to examine the hypotheses.ResultsEmpirical results demonstrate that (a) employee innovative behavior is directly and positively related to workplace wellbeing, (b) employee innovative behavior is indirectly and positively related to workplace wellbeing through leader support for innovation, and (c) the negative association between employee innovative behavior and workplace wellbeing via coworker ostracism is unsupported.DiscussionThe findings of this study enrich the literature by exploring the double-edged sword effect of employee innovative behavior on workplace wellbeing. The practical implications of this study are that leaders in organizations should give employees innovation support.
Association of individual resilience with organizational resilience, perceived social support, and job performance among healthcare professionals in township health centers of China during the COVID-19 pandemic
Authors: Wang An-Qi , Tang Chang-Hai , Song Jia , Fan Cheng-Xin , Wang Wan-Chen , Chen Zhong-Ming , Yin Wen-Qiang 
Published: November 2022

BackgroundPrimary healthcare professionals were overworked and psychologically overwhelmed during the COVID-19 pandemic. Resilience is an important shield for individuals to cope with psychological stress and improve performance in crises. This study aims to explore the association of individual resilience with organizational resilience, perceived social support and job performance among healthcare professionals in township health centers of China during the COVID-19 pandemic.MethodsData from 1,266 questionnaires were collected through a cross-sectional survey conducted in December 2021 in Shandong Province, China. Descriptive analysis of individual resilience, organizational resilience, perceived social support, and job performance was conducted. Pearson correlation analysis was used to examine the correlations among these variables, and structural equation modeling was performed to verify the relationships between these variables.ResultsThe score of individual resilience was 101.67 ± 14.29, ranging from 24 to 120. Organizational resilience (β = 0.409, p &lt; 0.01) and perceived social support (β = 0.410, p &lt; 0.01) had significant direct effects on individual resilience. Individual resilience (β = 0.709, p &lt; 0.01) had a significant direct effect on job performance. Organizational resilience (β = 0.290, p &lt; 0.01) and perceived social support (β = 0.291, p &lt; 0.01) had significant indirect effects on job performance.ConclusionDuring the COVID-19 pandemic, the individual resilience of healthcare professionals in township health centers was at a moderate level. Organizational resilience and perceived social support positively affected individual resilience, and individual resilience positively affected job performance. Furthermore, individual resilience mediated the effect of organizational resilience and perceived social support on job performance. It is recommended that multiple stakeholders work together to improve the individual resilience of primary healthcare professionals.
Non-pharmacological interventions for behavioral and psychological symptoms of dementia: A systematic review and network meta-analysis protocol
Authors: Li Ya-Qin , Yin Zi-Han , Zhang Xin-Yue , Chen Zheng-Hong , Xia Man-Ze , Ji Lai-Xi , Liang Fan-Rong 
Published: November 2022

IntroductionDementia patients often experience behavioral and psychological symptoms (BPSD), which severely affect their quality of life and activities of daily living. Non-pharmacological interventions are effective in treating BPSD, according to multiple clinical trials and systematic reviews. However, the optimal non-pharmacological treatment remains controversial. Therefore, the study aims to evaluate and compare multiple non-pharmacological methods for treating BPSD in order to identify the optimal non-pharmacological intervention.ObjectiveThis study aims to perform a systematic review and network meta-analysis of evidence on non-pharmacological interventions in the treatment of BPSD, which may potentially guide future research and clinical decisions.MethodsIn order to select potentially relevant randomized controlled trials (RCTs), 10 academic databases and 3 clinical trial registries will be systematically searched from inception until the 1 October 2022. Two researchers will independently extract information from eligible articles. The primary outcome is the severity of BPSD. Herein, Pairwise and Bayesian network meta-analyses will be conducted utilizing STATA 15.0 and ADDIS 1.16.8. Evidence quality will be assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE).ResultsResults from this study will be published in peer-reviewed journals or conference reports.DiscussionIn this study, we aim to comparatively assess the efficacy of various non-pharmacological treatments for BPSD. Findings from this review will help clinicians to make evidence-based treatment decisions.Systematic review registration[https://www.crd.york.ac.uk/prospero/], identifier [CRD42022352095].
How to promote grass roots medical treatment under China's graded diagnosis and treatment policy? — From the perspective of customer value theory
Authors: Tao Wanqiong , Chen Xiangrui , Gan Shuyu 
Published: November 2022

ObjectivesBased on the background of the implementation of graded diagnosis and treatment policy (GDT) in China, this paper studied the service optimization of primary medical institutions from the perspective of the primary medical treatment rate.MethodsFirst, the difference-in-difference (DID) empirical strategy is used to analyze the impact of the implementation of the GDT on the improvement of the primary medical attendance rate, and the parallel trend test and the placebo test were used to test the robustness to illustrate the necessity of policy implementation. Second, combined with customer value theory, this paper used a logistic regression model to study the impact of customer value perception on grassroots medical care.ResultsThe implementation of the GDT can indeed improve the rate of primary care (p = 0.028), but the impact is relatively small (0.042). From the perspective of value perception hierarchy, emotional value perception (p &lt; 0.05) is the key factor that affects the behavior of grassroots medical treatment at this stage.ConclusionThis paper fills the gaps in existing research, including empirical research on the grassroots medical treatment behavior of the masses under GDT and the impact of value perception on grassroots medical behavior. Furthermore, the recommendations are made for primary care institutions based on the results of the analysis, which promote the advancement of primary care services in China.
Power and resistance in schools: Implementing institutional change to promote health equity for sexual and gender minority youth
Authors: Shattuck Daniel , Richard Bonnie O. , Jaramillo Elise Trott , Byrd Evelyn , Willging Cathleen E. 
Published: November 2022

IntroductionSchools in the United States are hierarchical institutions that actively (re)produce the power relations of the wider social world, including those associated with heteronormativity. Structural stigma, informed by heteronormativity and perpetuated through schools, contributes to the production of academic and health disparities among youth who are lesbian, gay, bisexual, transgender, queer, or of other gender and sexual identities (LGBTQ+). We draw upon 5 years of qualitative data from a cluster randomized controlled trial conducted in New Mexico that used implementation science frameworks to promote the uptake and sustainment of evidence-informed practices (EIPs) to examine how power operates to hinder or promote the ability of school staff to change school environments, disrupt structural stigma, and increase safety and support for LGBTQ+ youth.MethodsData sources included annual individual and small group qualitative interviews with school professionals (e.g., administrators, school nurses, teachers, and other staff), several of whom took part in Implementation Resource Teams (IRTs) charged with applying the EIPs. Other data sources included bi-weekly periodic reflections with implementation coaches and technical assistance experts. Data were recorded, transcribed, and analyzed using deductive and inductive coding techniques.ResultsThe IRTs experienced variable success in implementing EIPs. Their efforts were influenced by: (1) constraining school characteristics, including staff turnover and resource scarcity; (2) community-based opposition to change and concerns about community backlash; (3) the presence or absence of supportive school leadership; and (4) variations in school, district, and state policies affecting LGBTQ+ students and attitudes about their importance. Findings illustrate how diverse power structures operated in and across outer and inner contexts to bound, shift, amplify, and otherwise shape how new practices were received and implemented.ConclusionFindings indicate that the efforts of IRTs were often a form of resistant power that operated within and against school hierarchies to leverage epistemic, discursive, and material power toward implementation. To improve health equity, implementation scientists must attend to the multiple real and perceived power structures that shape implementation environments and influence organizational readiness and individual motivation. Implementers must also work to leverage resistant power to counter the institutional structures and social norms that perpetuate inequities, like heteronormativity and structural stigma.
An Indigenous critique: Expanding sociology and recognizing unique Indigenous knowledge
Authors: Mackay Ried E 
Published: November 2022

IntroductionThis essay suggests that sociologists should integrate into their critical research work on the Americas an Indigenous critique/method based on Indigenous knowledge. As a mixed Indigenous scholar, I have been frustrated by the lack of frameworks based explicitly on Indigenous knowledge rather than merely referencing that knowledge.MethodsStrong foundations of ancient Indigenous thought and philosophical tradition—which often differs dramatically from Western traditions—are identified and explored through three concepts: Ch'ixi, the Indigenous pragmatic, and Mexica concepts of Truth. These are identified and discussed using authoritative historical and contemporary sources. I provide potential pathways for usage of these concepts in the results and discussion. Arguments and controversy for accepting the validity of Indigenous sources are also addressed.Results and discussionDiscussions of specific empirical questions and puzzles related to already familiar concepts and analyses such as systemic racism theory, multi-raciality, religion, and postcolonial theory are explored. The paper concludes that Indigenous theory is underexplored but is critical to liberation of Indigenous people and has legitimate academic value that scholars need to recognize.
Evaluating Germplasm of Cultivated Oat Species from the VIR Collection under the Russian Northwest Conditions
Authors: Popov Vitaliy S. , Khoreva Valentina I. , Konarev Alexei V. , Shelenga Tatyana V. , Blinova Elena V. , Malyshev Leonid L. , Loskutov Igor G. 
Published: November 2022

Oat is one of the most widespread and important cereal crops in the global agricultural production. Searching for new high-yielding and nutritious forms continues to be relevant, especially under the global trend of climate change, when most local oat cultivars may become economically inefficient. Spring oat accessions from VIR collection served as the material for this study; their origin is diverse, as they came from 11 countries. The basic nutritional value (the content of protein, oil, starch, and β-glucans) and characters important for breeding (plant height, panicle length, number of spikelets, number of grains per panicle, 1000 grain weight, and grain yield) were analyzed in 49 accessions of the cultivated covered oat species: Avena sativa L., A. strigosa Schreb., A. abyssinica Hochst., and A. byzantina Coch., grown under the conditions of the Russian Northwest (Leningrad Province) for two years. Variability parameters, interspecific and intervarietal differences, and the effect of weather conditions were assessed. Sources of useful agronomic traits were identified; they can be used to expand the range of the source material for the development of new high-yielding and highly nutritious oat cultivars adapted to local cultivation conditions. It is demonstrated that the VIR collection has a great potential for contemporary food and feed production and for the breeding of new oat cultivars for various purposes. Thus, the contribution of Nikolai Vavilov to the plant genetic resources investigation for the benefit of humanity is invaluable.
MPCVD diamond-SiC composite stacks for enhanced thermal performance: a concise review
Authors: Hu Xiufei , Wang Yingnan , Peng Yan , Cheong Kuan Yew , Han Jisheng , Wang Xiwei , Li Bin , Yang Yiqiu , Xu Mingsheng , Xu Xiangang 
Published: November 2022

Abstract
Diamond-silicon carbide (SiC) composite stacks are composed of two kinds of wide-bandgap materials, each of which has excellent thermal, electronic, optical, and mechanical properties, and is considered an ideal material for heat dissipation. For optimal application, the interface between the two materials needs to be almost void-free and of high-quality growth. Traditional methods such as sintering and liquid/vapor phase infiltration have many problems, but the preparation of diamond-SiC composites by the microwave plasma chemical vapor deposition (MPCVD) method can effectively solve these problems, overcome the interface defects, and break through the size limitation. In this review, various techniques for preparing diamond-SiC composites by MPCVD will be discussed. It mainly includes the co-deposition of diamond and cubic polytype β-SiC, deposition of diamond films on β-SiC/Si substrates, and deposition of diamond films on 4H-SiC and 6H-SiC substrates. The implementation methods, research progress, and application trend of each approach are reviewed in detail.
Enhanced contact properties of MoTe2-FET via laser-induced heavy doping
Authors: Xie Tianshun , Fukuda Kazuki , Ke Mengnan , Krüger Peter , Ueno Keiji , Kim Gil-Ho , Aoki Nobuyuki 
Published: November 2022

Abstract
The doping technique is vital for applying two-dimensional (2D) materials such as transition metal dichalcogenide (TMDC)-based field effect transistors (FETs), which can control the channel polarity and improve the performance. However, as conventional doping techniques for silicon-based FET are not suitable for 2D materials, the realization of heavy doping of TMDC materials is challenging, especially for n-type heavy doping. This study reports a simple, regioselective, controllable, and chemically stable heavy doping method for 2H-MoTe2 crystal via high-density laser irradiation. The polarity of the doping can be controlled by changing the irradiation environment. For the MoTe2-nFET, good performance with enhanced contact properties was obtained using the contact doping method via laser irradiation in a vacuum environment.
EFEKTIVITAS CENDAWAN MIKORIZA ARBUSKULAR TERHADAP PERTUMBUHAN TANAMAN JAGUNG (Zea mays) DALAM MEDIA TANAH TERCEMAR HIDROKARBON
Authors: Elhany Nurul Avidhah , Hapsari Rini , Husnudin Uni Baroroh , Ratnasari Desy 
Published: November 2022

Jagung (Zea mays) adalah salah satu tanaman yang mudah berkolonisasi dengan Cendawan Mikoriza Arbuskular (CMA). Penelitian ini bertujuan untuk mengetahui konsentrasi CMA, konsentrasi minyak dan kombinasi antara konsentrasi CMA dan konsentrasi minyak dalam melakukan pertumbuhan tanaman jagung (Zea mays). Pada penelitian ini digunakan uji statististik dengan rancangan penelitian faktorial terdiri dari dua faktor. Faktor pertama adalah 5 konsentrasi CMA yaitu 0 g, 5 g, 20 g, 35 g, 50 g dan faktor kedua adalah 4 konsentrasi minyak yaitu 0 mg, 2500 mg, 5000 mg, 10000 mg. Masing-masing polybag yang diberi perlakuan penambahan CMA dan minyak juga diberi tanah dan kompos dengan perbandingan (1:1). Crude oil diambil dari lokasi pengeboran minyak di Kec.Wonocolo, Kab.Bojonegoro, Jawa Timur. Parameter pertumbuhan tanaman jagung di ukur 35 hari setelah tanam. Hasil penelitian menunjukkan bahwa konsentrasi CMA, konsentrasi minyak, kombinasi antara konsentrasi CMA dan konsentrasi minyak berpengaruh terhadap pertumbuhan tanaman jagung (Zea mays). Konsentrasi CMA terbaik dalam pertumbuhan tanaman jagung adalah konsentrasi CMA 50 g dengan parameter tinggi tanaman sebesar 145 cm dan panjang akar sebesar 22 cm.