bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of COVID-19 Infection on Macular Capillary Perfusion
Authors: baris mine esen , Degirmenci Cumali , Yilmaz Suzan Guven , Afrashi Filiz , Pullukcu Husnu , Tasbakan Meltem 
Published: January 2022

Abstract
Purpose: To evaluate the impact of a prior non-severe COVID-19 infection on retinal microcirculation with optical coherence tomography angiography (OCTA).Methods:A total of 83 eyes of 43 patients with a history of non-severe COVID-19 infection confirmed with a positive PCR test (Group 1) and 30 age-matched healthy controls (Group 2) underwent detailed eye examination including Spectral-Domain OCT (Topcon-Triton Swept Source) and OCTA (RTVue-XR Avanti) scanning. OCTA images (6x6mm) images were used to assess vessel densities (VD) in superficial capillary plexus (SCP) and deep capillary plexus (DCP) and foveal avascular zone (FAZ). Results:The mean duration between the COVID-19 positive PCR test and ocular examination was 144.6±82.2 days (range: 30-270). VD of SCP and DCP in the foveal and perifoveal regions were significantly lower in Group 1 compared to Group 2 (p<0.05). Conclusion:Non-severe COVID-19 infection may cause a decrease in VD of retinal SCP and DCP.
Nodulation Compatibility and Symbiotic Performance of Rhizobia spp. With Different Landraces of Bambara Groundnut (Vigna Subterranea (L.) Verdc.) Collections
Authors: Hassen Ahmed Idris Idris , Vuuren Ansa van , Bopape Francina Lebogang , Gerrano Abe Shegro 
Published: January 2022

Abstract
The symbiosis of the legume bambara groundnut (Vigna subterranean L.Verde) with its rhizobial partners has not been studied sufficiently compared to several other legumes throughout Africa. In this study, a nodulation compatibility screening was conducted on 16 different landraces of this legume using five Rhizobia strains previously isolated from active nodules of Desmodium uncinatum, Arachis hypogaea, Cyamopsis tetragonoloba, Glycine max and Phaseolus vulgaris and deposited at the South African Rhizobium Culture Collection (SARCC). A screening assay was conducted under glasshouse to select compatible rhizobia strains that nodulate and enhance growth in one or more genotypes of V. subterranean (L.) Verdc. Pre-germinated seeds of each landraces planted in sterile river sand medium were inoculated with 108 cfu ml-1 of the rhizobial strains (2ml/seed) and monitored with regular watering for six weeks. Parameters such as nodule number, nodule color and positions, plant biomass were determined in test genotypes. Significant differences were observed among landraces in nodule number and plant biomass, and among rhizobial strains in nodule number. Principal component analysis (PCA) showed that root nodule rhizobia strains SARCC-388 and SARCC-578 characterized as Bradyrhizobium zhangiangens and Bradyrhizobium centrosematis, respectively exhibited the highest nodulation compatibility with one or more bambara groundnut landraces. This study demonstrated that many of the bambara landraces did not show nodulation preference to a unique group of rhizobia, confirming that V. subterranean (L) Verdc can be nodulated by more than one species of rhizobia, especially by rhizobia belonging to the cowpea miscellany cross inoculation group.
Acquisition of Rainfall in Ungauged Basins: a Study of Rainfall Distribution Heterogeneity Based on a New Method
Authors: Zhao Ye , zhang Xiang , xiong feng , Liu Shuying , wang yao , liang changmei 
Published: January 2022

Abstract
High-density precipitation data is always desired to capture the heterogeneity of precipitation to accurately describe the components of the hydrological cycle. However, equipping and maintaining a high-density rain gauge network involves high costs, and the existing rain gauges are often unable to meet the density requirements. The objective of this study is to provide a new method to analyze the spatiotemporal variability of the precipitation field and to solve the problem of insufficient site density. To this end, the Proper Orthogonal Decomposition (POD) method is proposed, which can analyze the spatial distribution characteristics of rainfall fields to solve data shortages. To demonstrate the feasibility and advantages of the proposed methodology, four districts and counties (Hongshan District, Jianli County, Sui County, and Xuanen County) in Hubei province in China were selected as case studies. The principal results are as follows. (1) The proposed method is effective in analyzing the spatiotemporal variability of the rainfall field to reconstruct rainfall data in ungauged basins. (2) Compared with the commonly used Thiessen Polygon method, the Inverse Distance Weighting method, and the Kriging method, POD is more accurate and convenient, and the root mean squared error is reduced from 3.22, 1.83, 2.19 to 2.09; the correlation coefficients are improved from 0.60, 0.85, 0.79 to 0.89, respectively. (3) The POD method performs particularly well in simulating the peak value and the peak time and can offer a meaningful reference for analyzing the spatial distribution of rainfall.
The Effects of Taxation on Economic Development: the Moderating Role of Tax Compliance Among SMEs
Authors: Werekoh Eugene Adjei 
Published: January 2022

Abstract
The amount of revenue collected often determines a country's economic growth and development. Taxes continue to be one of the most important constituents in managing nationwide income in emerging and developed nations. In this sense, tax evasion might have serious effects, especially because the global cost of non-compliance by taxpayers is quite significant. Small and medium-sized firms (SMEs) are the backbone of economies around the world, driving economic progress and growth, as well as innovation and wealth creation. The high incidence of tax non-compliance among SMEs, on the other hand, stymies the progress that SMEs are meant to bring to many nations. Thus, the study aim at assessing the effects of taxation on economic development with its moderating role of tax compliance. The descriptive research design with quantitative approach was employed. The population of the study consist is 10,000 SMEs operating in Kumasi currently with a sample size of 400 SMEs. The instrument for data collection in this study was questionnaire. The data that was collected was analysed using SPSS. The findings demonstrated that in formulating strategies to enhance voluntary compliance, it is crucial for the relevant authorities to be aware of, understand and appreciate taxation taxpayers’ compliance behaviour and the need to provide tax education services. The results indicated that tax compliance enhanced the effectiveness of taxation to impact on economic development. The moderating role of tax compliance in the relationship between taxation and economic development was low but positive.
Only Cervical Segments C0-C2, Not C3 Are Relevant for Subgrouping Migraine Patients According to Manual Palpation and Pain Provocation
Authors: Schwarz Annika , Luedtke Kerstin , Schoettker-Koeniger Thomas 
Published: January 2022

Abstract
Background and Aims: Subgrouping of migraine patients according to the pain response to manual palpation of the upper cervical spine has been recently described. Based on the neuroanatomy and the convergence of spinal and trigeminal nerves in the trigeminocervical complex, the cervical segments C1 to C3 are potentially relevant. To date it has not been investigated whether palpation results of all upper cervical segments are based on one underlying construct which allows combining the results of several tests.Methods: Seventy-one migraine patients with chronic or frequent episodic migraine diagnosed according to the IHS classification version 3 were examined by one physiotherapist. Manual palpation was performed on the upper three cervical segments unilaterally left and right. The results of the palpation according to the patients’ responses were combined using factor analysis to determine whether results from all three segments form one underlying construct. In addition, item response theory (IRT) was used to investigate the structure of the response pattern as well as item difficulty and discriminationFindings: Factor analysis (principal component) showed that the palpation of C3 loads less onto the underlying construct than the palpation of C1 and C2. Considering a cut-off value >1.0, the eigenvalues of all three segments do not represent one underlying construct. When excluding the results from C3, remaining items form one construct. The internal consistency of the pain response to palpation of C1 and C2 is acceptable with a Cronbach’s alpha of 0.69. IRT analysis showed that the rating scale model fits best to the pain response pattern. The discrimination value (1.24) was equal for all 4 items. Item difficulty showed a clear hierarchical structure between the palpation of C1 and C2, indicating that people with a higher impairment are more likely to respond with referred pain during palpation of the segment C2. Conclusion: Statistical analysis confirms that results from the palpation of the cervical segments C1 and C2 in migraine patients can be combined. IRT analysis confirmed the ordinal pattern of the pain response and showed the higher probability of a pain response during palpation of C2. Registration of main Study: German registry of clinical trials (DRKS00015995), Registered 20. December 2018, https://www.drks.de/drks_web/setLocale_EN.do
Rhino Orbital Cerebral Mucormycosis in settings of Covid-19 infection: A Case Series of Thirteen Patients
Authors: Verma Rajesh , Chakraborty Rajarshi , DB Keerthiraj , Wangda Kingzang , Verma Veerendra , Gupta Prashant 
Published: January 2022

Abstract
Background

Rhino-Orbital-Cerebral Mucormycosis (ROCM) is an important infectious disease encountered in huge number in this recent post-covid 19 era. An alteration in defence immune system during covid-19 illness, in the presence of uncontrolled hyperglycaemia has led to the new epidemic of ROCM especially in developing nations like India.
Method

This case series of thirteen patients illustrates the various clinical presentation, laboratorical parameters, imaging features and outcome of patients of ROCM admitted in a tertiary care hospital in Northern India.
Result

In our case series, a total of 13 newly diagnosed cases of Rhino-Orbital-Cerebral Mucormycosis were studied. History of covid-19 illness was observed in 7 cases (53.8%), use of steroid during Covid-19 illness was seen in 5 cases (38.5%), oxygen therapy was given in 4 cases (30.8%). Co-morbid state in the form of diabetes mellitus was present in 12 cases (92.3%) with mean duration 16.69 months with an important finding of 6 cases (46.2%) having new-onset diabetes; hypertension in present in 3 cases (23.1%). Magnetic resonance imaging of paranasal sinuses showed involvement of multiple sinuses in all the 13 cases(100%), including maxillary and ethmoidal sinuses, with frontal in 12 cases (92.3%), sphenoidal in 11 cases (84.6%), symmetric in 9 cases (69.2%), mastoiditis in 4 cases (30.8%), maxillary space involvement in 4 cases (30.8%), palatal involvement in 1 case (7.7%). Multi-speciality approach treatment was given in the liposomal amphotericin B therapy in all the patients along with thorough endo-nasal debridement done in all cases, transcutaneous retrobulbar amphotericin B in 6 cases (46.2%) with exenteration done in 7 patients (53.9%). At 3 months of follow-up, there was substantial clinical improvement in all the cases.
Conclusion

There should be definite emphasis on high suspicion of mucor clinically for early diagnosis and aggressive management at initial state of diagnosis for better outcome. The need for sustained proper glycemic control during covid 19 era along with judicious use of steroid and public awareness for early symptoms and manifestations of mucor can curb the magnitude of such potentially opportunistic epidemic to a substantial rate. The longer the infection remains undetected, the greater the devastation ROCM can impose, of which blindness is an important hazard.
Ferroptosis Regulators and Tumor Microenvironment Immune Cell Infiltration Characterization in Adrenocortical Carcinoma
Authors: Shen Chengquan , Liu Jing , Liang Ye , Liang Zhijuan , Wang Liping , Chen Yuanbin , Li Dan , Wang Yonghua 
Published: January 2022

Abstract
Background

Adrenocortical carcinoma (ACC) is a rare disease with a poor prognosis and lacking effective systemic treatment options. Recent studies showed that ferroptosis play a prominent role in the initiation and development of cancer. Nonetheless, the potential roles of ferroptosis regulators in the prognosis and tumor microenvironment immunomodulator factors expression remain not fully study.
Methods

TCGA and GEO ACC datasets were used to investigate the relationship between ferroptosis regulators with prognosis and clinical features. Consensus clustering analysis was performed to divided ACC patients into different ferroptosis subgroups. A ferroptosis scoring system was established for individual ACC using principal component analysis algorithms. The correlation between ferroptosis score and tumor microenvironment immune cell infiltration was analyzed.
Results

Twenty ferroptosis regulators were differentially expressed in ACC and 17 ferroptosis regulators were closely related to the prognosis of ACC. Three ferroptosis subgroups (Cluster A, B, and C) were determined based on the expression of ferroptosis regulators. Cluster C is preferentially associated with favorable OS, PFS, upregulated antigen-presenting genes expression, and higher immune cell infiltration. GSEA also indicated that Cluster C was prominently related to immune fully activation including chemokine signaling pathway, natural killer cell-mediated cytotoxicity, T cell receptor signaling pathway, and Toll-like receptor signaling pathway. A ferroptosis scoring system was constructed and it could serve as an independent prognostic factor for ACC. The ferroptosis scores were significantly correlated with TMB, immune-checkpoint genes expression, and tumor microenvironment immune cell infiltration in ACC. Further analyses indicated that the ferroptosis score integrated with TMB, immune-checkpoint genes expression, and CD4+ T cell infiltration, could predict the prognosis of ACC. Furthermore, a nomogram was constructed to monitor the prognosis of individual ACC patient. RNA isolation and reverse transcription‑quantitative PCR (RT-qPCR) demonstrated significant differences in the expression levels of ACSL4, FANCD2 and SLC7A1 between ACC and normal tissues.
Conclusion

Our study demonstrated ferroptosis regulators were significantly associated with the prognosis, clinical characteristics, immune-checkpoint genes expression, and tumor microenvironment immune cell infiltration in ACC. This current study provided comprehensive evidence for further research on ferroptosis regulators in ACC and provides new enlightenment for epigenetic regulation of antitumor immune response.
Whole Body Muscle Activity During Weightlifting Exercise Evaluated By Positron Emission Tomography
Authors: Yoshimizu Rikuto , Nakase Junsuke , Mochizuki Takafumi , Takata Yasushi , Shimozaki Kengo , Asai Kazuki , Toyooka Kazu , Kimura Mitsuhiro , Kinuya Seigo , Tsuchiya Hiroyuki 
Published: January 2022

Abstract
Background: This study investigated the whole-body skeletal muscle activity pattern of hang power clean (HPC), a major weight training exercise, using positron emission tomography (PET). Methods: Twelve college weightlifting athletes performed three sets of HPC 20 times with a barbell set to 40 kg both before and after an intravenous injection of 37 MBq 18F-fluorodeoxyglucose (FDG). PET-computed tomography images were obtained 50 min after FDG injection. Regions of interest were defined within 71 muscles. The standardized uptake value was calculated to examine the FDG uptake of muscle tissue per unit volume, and FDG accumulation was compared to the control group. The Mann–Whitney U-test was used to evaluate the differences in the mean SUV between groups. The difference between SUVs of the right and left muscles was evaluated by a paired t-test. A P-value <0.05 was considered statistically significant.Results: FDG accumulation within the vastus lateralis, vastus intermedius, and vastus medialis was higher than that of the rectus femoris. FDG accumulation within the triceps surae muscle was significantly higher only in the soleus. In the trunk and hip muscles, FDG accumulation of only the erector spinae was significantly increased. In all skeletal muscles, there was no difference between SUVs of the right and left muscles.Conclusions: The monoarticular muscles in the lower limbs were active in HPC. In contrast, deep muscles in the trunk and hip were not active during HPC. HPC is not suitable for core training and needs to be supplemented with other training.
Public Health Events Emergency Management Supervision Strategy Considering New Media and Citizen Participation
Authors: Lu Bingjie , Zhu Lilong 
Published: January 2022

Abstract
Public health events endanger the citizen health, economic development, social stability and national security seriously. Emergency management requires the joint participation of multiple parties. Therefore, we construct an evolutionary game model involving government department, pharmaceutical enterprises, citizens and new media, analyze the evolutionary stability, solve the stable equilibrium points using the Lyapunov first method and conduct the simulation analysis with Matlab 2020b. The results show that, firstly, the greater the probability of citizens making true evaluation, the more inclined the government department is to strictly implement the emergency management system, and when true evaluation causes the government department to bear more punishment, the probability that the government department doesn't strictly implement is smaller; secondly, when the probability of citizens making true evaluation decreases, new media are more inclined to report after verification, and when new media lose more pageview value or should be punished more for reporting without verification, the probability that they report without verification is smaller; thirdly, the greater the probability of citizens making false evaluation, the less enthusiasm of pharmaceutical enterprises to participate in emergency management, which indicates that false evaluation is detrimental to prompt pharmaceutical enterprises to participate; what's more, the greater the probability of new media reporting after verification, the greater the probability of pharmaceutical enterprises actively participating, which shows that new media's verification to citizens' evaluation is beneficial to emergency management. So, this paper provides suggestions for the emergency management and supervision.
Establishment of a New Equation for Ultrasonographic Estimated Foetal Weight in Chongqing: a Prospective Study
Authors: Wu Chenhuizi , Sun Jianfeng , Dong Xiaojing , Cai Liuyun , Deng Xinru , Zhang Fenglan , Shu Yang , Zhang Maochao , Luo Xiaodong 
Published: January 2022

Abstract
Background: Variations in foetal growth between populations should not be ignored, and a single universal standard is not appropriate for everyone. Therefore, it is necessary to develop a new ultrasound estimation equation that adapts better to regional population characteristics. The purpose of this study was to create a new equation for ultrasound estimation of foetal weight according to the local population in Chongqing and compare it with representative equations. Methods: This prospective study included data on pregnant women who gave birth to a child at full term in our hospital from December 2016 to November 2019. Foetal ultrasound parameters included biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), and femur diaphysis length (FDL). The foetal weight compensation model was established by using the second-order linear regression model, and then, the foetal weight equation was established by utilizing the multiple reverse elimination regression technique. Last, the absolute error and relative error were used to compare the accuracy of the equations established in this study with representative equations. Results: Through the foetal weight compensation equation, the new equation suitable for Chongqing foetuses was successfully established with the variables of BPD, HC, AC, and FDL. The following foetal weight prediction equation was established in this study: Log 10 (EFW)=3.002741+0.00005944*(BPD^2)+0.00000222*(HC^2)-0.000002078*(AC^2)+0.00004262*(FDL^2)-0.008753*BPD-0.000884*HC+0.003206*AC-0.002894*FDL (BPD: mm; HC: mm; AC: mm; FDL: mm). In the sets established by the 1925 data, the mean absolute error and standard deviation of the estimation error of the new equation were 178.9 g and 140.3 g respectively. In the validation sets established with 300 data points, the mean absolute error and standard deviation of the new equation were 173.08 g and 128.59 g respectively. Compared with representative equations, the mean absolute error and the standard deviation of the new equation were the lowest. The equation established in this study better predicted foetal weight(P<.001). Conclusions: According to the local population characteristics of Chongqing, this study created a foetal weight estimation equation that is more accurate and suitable. This equation is clinically valuable for the monitoring and management of foetal weight.
Research on calculation of grinding surface roughness
Authors: Tran Thi Van Nga , Nguyen Lam Khanh , Nguyen Van Cuong 
Published: January 2022

In machining processes, grinding is often chosen as the final machining method. Grinding is often chosen as the final machining method. This process has many advantages such as high precision and low surface roughness. It depends on many parameters including grinding parameters, dressing parameters and lubrication conditions. In grinding, the surface roughness of a workpiece has a significant influence on quality of the part. This paper presents a study of the grinding surface roughness predictions of workpieces. Based on the previous studies, the study built a relationship between the abrasive grain tip radius and the Standard marking systems of the grinding wheel for conventional and superabrasive grinding wheels (diamond and CBN abrasive). Based on this, the grinding surface roughness was predicted. The proposed model was verified by comparing the predicted and experimental results. Appling the research results, the surface roughness when grinding three types of steel D3, A295M and SAE 420 with Al2O3 and CBN grinding wheels were predicted. The predicted surface roughness values were close to the experimental values, the average deviation between predictive results and experimental results is 15.11 % for the use of Al2O3 grinding wheels and 24.29 % for the case of using CBN grinding wheels. The results of the comparison between the predicted model and the experiment show that the method of surface roughness presented in this study can be used to predict surface roughness in each specific case. The proposed model was verified by comparing the predicted and measured results of surface hardness. This model can be used to predict the surface hardness when surface grinding