bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ethnobotanical survey of some medicinal plants used in the treatment of schistosomiasis in Sokoto mteropolis, Sokoto State, Nigeria
Authors: Mana Usman , Bunza Muhammad , Attah Dan-inna , Sani Ibrahim 
Published: February 2022

Schistosomiasis is a parasitic disease that affect the well-being of people in Sokoto State-Nigeria. A survey of medicinal plants used in the treatment of schistosomiasis was conducted in Kware/Wammakko Local Government areas of the state through the administration of structured questionnaire. The survey from 48 respondents revealed total 9 plant species belonging to different families were found to be frequently used in treatment of schistosomiasis. Qualitative and quantitative phytochemical analyses on the plants revealed the presence of secondary metabolites. In Acacia nilotica, flavvnoids (3.53 %), alkaloids (2.3 %), saponins (1.507 %), tannins (64 mg/dl), glycosides (0.32 g%), and steroids (79 mg%) were found to be present. In Balanites aegyptiaca, flavvnoids (2.66 %), alkaloids (2.6 %), saponins (1.05 %), tannins (72 mg/dl), glycosides (0.30 g%) and steroids (91 mg%) were present. In Khaya senegalensis, flavnoids (0.77 %), alkaloids (1.8 %), saponins (0.5 %), tannins (23 mg/dl), glycosides (0.23 g%), and steroids (65 mg%) present. The snails were exposed to different concentrations of plant extracts for 96 hours. Ten experimental snails were exposed to 3 L of water containing 3 plant extracts. Mortality was recorded after every 24hr. to 96hr. No response to needle touch was taken as evidence of death. Dead snails were removed immediately to avoid contamination. The toxicity of the three the plant extracts decreased from 255.10 mg/L (42.7%) 24 hr, 91.61 mg/L (21.1%) 48 hr, 66.74 mg/L (21.6%) 72hr and 100% mortality in 96 hr. The toxicity was found to be time and dose dependent. The data obtained from this research have provided the scientific basis for the use of these plants in treatment of schistosomiasis and these plant could serve as effective, cheap and affordable source of medicinal agents for control of schistosomiasis in the State.
Keywords: Ethnobotanical; Survey; Schistosomiasis; Sokoto; Nigeria
Isolation and characterization of some flavonoids from the leaf of Tapinanthus globiferus growing on Acacia nilotica
Authors: Buhari Muhammad , Dangoggo Sani , Mohammed Misbahu , Abubakar Hassan , Muhammad Abubakar , Dambatta Mubarak , Yusuf Amina 
Published: February 2022

Tapinanthus globiferus is used ethnomedicinally for the treatment of bacterial infections, inflammation, stomach pain, ulcers among others. The aim of the study was to isolate bioactive compounds from the leaf of T. globiferus growing on Acacia nilotica. The powdered plant material was extracted with 90 % methanol using cold maceration and the resulting crude methanol leaf extract was partitioned into n-hexane, chloroform, ethylacetate and n-butanol fractions. The ethylacetate fraction was chromatographed on a silica gel, sephadex LH-20 column and preparative thin-layer chromatography. (-)-Epicatechin and Quercetin 3-O-β-D-glucopyranoside were isolated and characterized by means of physiochemical and spectroscopic (1D and 2D-NMR) analyses for the first time from T. globiferus growing on A. nilotica.
Keywords: Tapinanthus globiferus; Flavonoids; Isolation; NMR
Phytochemical and Antifungal Studies of Tapinathus globiferus Extract and Fractions
Authors: Tukur Muhktar , Abubakar Hassan , Yusuf Amina 
Published: February 2022

T. globiferus growing on Tamarindus indica is a hemi-parasitic plant used in ethomomedicine to treat different ailment including fungal infections. The aim of the study was to conduct phytochemical and antifungal studies of T. globiferus growing on Tamarindus indica. The plant material was collected, identified and air dried. Powdered plant material was subjected to maceration using methanol to obtained crude methanol leaf extract which was partitioned using n-hexane, chloroform ethyl acetate and n- The extract and the fractions obtained were subjected to phytochemical evaluation sing standard protocols. The antifungal studies of the methanol extract and its fractions against Aspergillus fumugatus, Aspergillus niger, Trychophytom rubrum and Trychophyton mentagrophyte were investigated using agar well diffusion method at different concentration (100 - 1.25 mg/mL). The phytochemical screening revealed the presence of various secondary metabolites which varies in the extract and fractions. The methanol extract and its fractions showed significant (p< 0.05) antifungal activity against all the fungal isolates with the ethyl acetate fraction having the highest zone of inhibition ranging from 10-39 mm then followed by the n-butanol fraction with the mean zone of inhibitions from 10-28 mm. The methanol extract and the n-hexane fraction recorded lower zone of inhibition from 9-24 mm and 8-26 mm respectively. The standard drug ketoconazole had zone of inhibition from 6-22 mm. The most sensitive organism was A. niger while the least sensitive organisms were T. mentagraphyte and A. rubrum for the ethyl acetate fraction. The study has validated the ethnomedicinal claim for the use of this plant in treatment of the fungal infections.
Keywords: Phytochemical; Tapinanthus globiferus; Tamarindus indica
Evaluación del nivel de sostenibilidad en la gestión de las tecnologías y sistemas de información a través de la Lógica Difusa Compensatoria
Authors: Lamis Rivero José Manuel , Plasencia Soler Juan Antonio , Marrero Delgado Fernando 
Published: February 2022

Las Tecnologías de la Información y las Comunicaciones han contribuido significativamente al desarrollo económico y social de la sociedad actual. La comunidad científica internacional está debatiendo sobre los efectos negativos y positivos de éstas y su relación con el medio ambiente y buscan soluciones en las tecnologías y sistemas de información sostenibles. El presente artículo propone un procedimiento para determinar el nivel de sostenibilidad en la gestión de tecnologías y sistemas de información a través del empleo de la Lógica Difusa Compensatoria en una organización. Los resultados de la aplicación del procedimiento permitieron calcular y evaluar el nivel de sostenibilidad en la gestión de sistemas y tecnologías de información. Tras analizar los resultados, se determinaron los criterios de medida peores evaluados entre los que se encontraron: la instalación de switches inteligentes, el despliegue de sistemas de enfriamiento libre, la implantación de tecnologías inteligentes, el uso de tecnología ecológica y la gestión de estrategias de Tecnologías y Sistemas de Información Sostenibles.
The Functional Strategy of PT. Kereta Api Indonesia (Persero) at UPT (Technical Implementation Unit) Jatinegara Locomotive Depot
Authors: Burhan Karunia 
Published: February 2022

Developments and changes in the business climate in industry era 4.0 now requires companies to be more careful in making to a decision that is comprehensive which later will underlie keput usan that is strategy . By formulating a strategy means the company has made a formulation of what must be done both at the corporate level (company), business and functional. In this study will be discussed about how the functional level strategy carried out by PT. Kereta Api Indonesia (Persero) / KAI at UPT (Technical Implementation Unit) Jatinegara Locomotive Dipo . UPT (Technical Implementation Unit) Jatinegara locomotive depot, a workshop for its fleet of locomotives busiest in Pul au serve the needs of Java in a series of long distance train relation 1 Jakarta area of operations throughout the regions of oper ation in Java. As a UPT which is very influential on the smooth supply of railroad services , an effective and efficient strategy is certainly needed . In the study, it will simulate the kaizen method in the UPT (Technical Implementation Unit) of the Jatinegara Locomotive Dipo in carrying out its functional strategy by making direct observations and comparing qualitative data from interviews .
Result of VATS surgery to treat stage III empyema at the Vietnam National Lung hospital
Authors: Khanh Nguyen Si , Dua Pham Thi Thanh , Tuan Dinh Van , Tuyen Nguyen Duc , Duc Dang Duy , Luong Dinh Van , Thanh Le Ngoc 
Published: February 2022

Objectives: To describe the clinical and laboratory features of stage III empyema and to evaluate the effectiveness and safety of using VATS surgery to treat stage III empyema at the Vietnam National Lung hospital.
Methods: Propective observational study. From 7/2019 to 01/2020 a total of 58 stage III empyema patients diagnosed who were treated at the Department of Thoracic Surgery – NLH were included in this study. Data were analyzed using SPSS software version 22.0Results: Among 58 patients with stage III empyema, 39 were treated by total VATS surgery, 19 by VATS as supported procedures. The mean age was 45±19.5 (17-85) years old. Male/female ratio :3.83. The main clinical symptoms were chest pain (81.0%), shortness of breath (70.7%), cough (60.3%). Average surgical time: 127.2±41.6(60- 250) minutes, draining time: 7.5±3 days, hospitalization time 10.3±3.4 (5-22) day. 96.6% of patients discharged with well conditions, confirmed by lung well-expanded lungs on Xrays, the success rate was 94.8%, and there was no patient death.Conclusion: Diagnosing stage III empyema was mainly based on clinical symptoms, chest HRCT. VATS surgery is the safe and effective technique, which helps to reduce surgery time, draining, lying down and reducing pain for patients.
Studying some electrophysiological characteristics of left atrial fibrillation in patients with paroxysmal atrial fibrillation (AF) and persistent atrial fibrillation (AF) by using a three-dimensional (3D) mapping system
Authors: Dung Le Tien , Thuy Nguyen Tran , Chuong Nguyen Huu Hong , Ba Vu Van , Linh Pham Tran , Khanh Pham Quoc 
Published: February 2022

Objective: To study some electrophysiological characteristics of left atrial fibrillation in patients with paroxysmal atrial fibrillation (AF) and persistent atrial fibrillation (AF) by using a three-dimensional (3D) mapping system.
Subjects and Methods: A cross-sectional descriptive study of 30 patients with atrial fibrillation (AF) (including 21 patients with paroxysmal AF and 9 patients with persistent AF) with indications for electrophysiological study and AF ablation under the support of a 3D mapping system, at the Cardiovascular Center of Hospital E and the Cardiology Department of 103 Military Medical Hospital during the period from Oct 2020 to Oct 2021.
Results: The mean age was 59.0 ± 11.0 years old, in which the percentage of men accounted for 60%, the mean duration of the disease was 2.2 ± 3.8 years, the symptom class affected the life quality, which was 3.24 ± 0.34 points, according to EHRA. Electrophysiological study results: For the group of persistent AF (n = 7), the average potential was 2.17 ± 0.30 mV, the lowest potential area in the septal region was 1.63 ± 0.38 mV, the potential at the atrial basal area was 1.8 ± 0.17 mV. For the paroxysmal AF group (n=21), the average potential was 2.70 ± 0.28mV, the lowest potential in the septal region was 1.95 ± 0.24 mV. The rate of potential areas <1.5 mV in the group of persistent AF was 28.5%, mainly located in the septum and posterior wall of the left atrium.
Conclusion: The average potential of the left atrial regions in the group of persistent AF was significantly lower than that of the patients with paroxysmal AF, low potential areas were found in 28.6% of the group of patients with persistent AF, located in the septum and base of the left atrium. There was no difference in sinus node recovery time and left atrial refractory time between the 2 groups.
Prostatectomía radical, radioterapia y vigilancia activa sin diferencias estadísticamente significativas en los resultados de mortalidad de pacientes con cáncer de próstata localizado
Authors: Orozco Martínez Abraham 
Published: February 2022

El cáncer de próstata es uno de los principales problemas de salud pública en la población adulta y la neoplasia más frecuente en hombres mayores de 40 años de edad. La Agencia Internacional de Investigación del Cáncer (GLOBOCAN) señala que la incidencia más alta se registra en Austria y América del Norte (111.6 y 97.2 casos por cada 100,000 hombres, respec tivamente) y la más baja en los países asiáticos (4.5 a 10.5 casos por 100,000 hombres). En África del Sur y el Caribe las tasas de mortalidad son más altas en poblaciones afrodescendientes (19 a 24 muertes por cada 100,000 hombres).
Primer estudio mexicano comparativo entre prostatectomía radical abierta y asistida por robot
Authors: Herrera Muñoz Javier Antonio 
Published: February 2022

ANTECEDENTES: hay controversia en cuanto a los resultados perioperatorios, oncológicos y funcionales entre la prostatectomía radical abierta versus prostatectomía radical laparoscópica asistida por robot.OBJETIVO: comparar los resultados perioperatorios, oncológicos y funcionales entre la prostatectomía radical abierta versus prostatectomía radical laparoscópica asistida por robot.MATERIALES Y MÉTODOS: estudio retrospectivo, descriptivo y analítico, efectuado mediante el análisis de los expedientes de pacientes posoperados de prostatectomía radical laparoscópica asistida por robot y prostatectomía radical abierta, de enero de 2012 a junio de 2016. Se analizaron variables preoperatorias (edad, estado funcional según los criterios del ECOG, comorbilidades, concentración de antígeno prostático específico, escala de Gleason y grupo de riesgo de la NCCN), perioperatorias (sangrando transoperatorio, tiempo quirúrgico, requerimiento de transfusión sanguínea, días de estancia hospitalaria, tiempo de permanencia de la sonda transuretral y complicaciones posquirúrgicas) y oncológicas (estadio clínico, criterios de Gleason de la pieza quirúrgica, márgenes positivos, persistencia y recurrencia bioquímica de la enfermedad; continencia urinaria [3, 6 y 12 meses] y potencia o desempeño sexual [6 y 12]). Para el análisis estadístico se utilizó el programa SPSS; se calcularon frecuencias y pruebas de normalidad. Se implementó la c2 de Pearson para variables cualitativas, y t de Student y U de Mann-Whitney para variables cuantitativas.RESULTADOS: se registraron 35 pacientes con prostatectomía radical laparoscópica asistida por robot y 36 con prostatectomía radical abierta. La edad media de los pacientes fue de 64 vs 63 años; tiempo quirúrgico de 286 ± 68 vs 225 ± 65 minutos (p<0.001); sangrando transoperatorio de 869 ± 657 vs 1567 1110 mL (p=0.001); tasa de transfusión de 37 vs 47% (p=0.26), respectivamente, y estancia hospitalaria de 5 días para ambos procedimientos. Se registraron complicaciones posquirúrgicas en 29 vs 28% (p=0.58) de los pacientes; márgenes positivos de 63 vs 33% (p=0.01) y tasa de continencia a los 3 meses de 57 vs 53% (p=0.7), respectivamente. El seguimiento de los pacientes con prostatectomía asistida por robot fue de 3 a 21 meses y de prostatectomía radical abierta de 1 a 4 años.CONCLUSIONES: este estudio confirma las ventajas de la prostatectomía radical laparoscópica asistida por robot: menor sangrado transoperatorio y de trasfusión; los parámetros restantes fueron similares, pero no inferiores, a los de la prostatectomía radical abierta. PALABRAS CLAVE: prostatectomía radical laparoscópica asistida por robot, prostatectomía radical abierta.
Comparison of the most popular methods for predicting stonefree rate after percutaneous nephrolithotomy
Authors: Ugalde-Resano Rodrigo , Villeda-Sandoval Christian Isaac , Kobashi-Sandoval Elisa , Rivera-Ramírez José Alejandro , Vargas-Robles Manuel Alexis , Méndez-Probst Carlos Enrique 
Published: February 2022

BACKGROUND: The Guy’s stone score, S.T.O.N.E. nephrolithometry, CROES nomogram, and S-ReSC scoring system have recently been externally validated as effective predictors of stone-free rate after percutaneous nephrolithotomy.OBJECTIVE: We describe herein the advantages of identifying the most accurate scale and propose its standardized use.MATERIALS AND METHODS: We analyzed 188 patients that underwent percutaneous nephrolithotomy for kidney stones within the time frame of October 2010 and July 2015 at a tertiary care referral center. Preoperative and postoperative non-contrast computed tomography scans were used in all patients to compare the four scoring systems, using the strict criterion of absolute absence of residual stone as the stone-free rate.RESULTS: The overall stone-free rate was 57.9%. All scoring systems presented a statistically significant stone-free rate (p<0.001). Only the Guy’s stone score had no correlation with postoperative complications. The four scoring systems had similar accuracy, none of them were more predictive for stone-free rate than the other, and there was no significant difference in the areas under the curve between them (p=0.2). In addition, each scale had a correlation with operative time and length of hospital stay.CONCLUSIONS: The four scales analyzed were excellent predictors for stone-free rate. They had similar receiver operating characteristic curves and areas under the curve, with no significant differences between them. However, the Guy’s stone score presented the best predictive capacity and the S-ReSC scoring system was the best method for predicting complications. It is up to the urologic community to decide which evidence-based scale is the most suitable. Meanwhile, the need for a standardized method continues to grow. KEYWORDS: Stone-free rate; Percutaneous nephrolithotomy; CROES; S-ReSC, S.T.O.N.E.; Guy’s stone score
Ureteritis quistica: reporte de un caso
Authors: Preciado Estrella Diego 
Published: February 2022

ANTECEDENTES: la ureteritis quística es una enfermedad excepcional caracterizada por formación de quistes (únicos o múltiples) en la luz ureteral; suele afectar a pacientes ancianos, en quienes se diagnostica incidentalmente en los estudios de imagen. Su incidencia es desconocida, pues existen pocos casos reportados en la bibliografía.CASO CLÍNICO: mujer de 68 años de edad, que inició 4 años antes de acudir a consulta con cólico renal izquierdo asociado con infecciones urinarias de repetición. Seis semanas antes del ingreso hospitalario acudió al servicio médico por fiebre, náuseas, vómito y dolor en la fosa renal izquierda. La tomografía computada reportó litiasis renal izquierda en el cáliz inferior, de 1 x 1.2 cm, por lo que se decidió realizar ureteroscopia y litotricia. Durante la ureteroscopia se observaron múltiples lesiones quísticas en todo el trayecto ureteral, principalmente en el tercio medio y superior. Se colocó un catéter JJ y en el segundo tiempo quirúrgico se completó la intervención con litotricia láser, fragmentando completamente el cálculo y verificando la desaparición de lesiones quísticas, encontrando solamente abundante sedimento asociado con el catéter.CONCLUSIONES: la ureteritis quística es una alteración poco frecuente relacionada con inflamación crónica. Dada su rareza, encontrarla puede suponer una alarma para el urólogo. Es importante efectuar urocultivos, solicitar estudios de imagen y ureteroscopia completa, con la finalidad de descartar algún tumor urotelial concomitante. PALABRAS CLAVE: ureteritis quística, infección de vías urinarias.
Del autor hasta su publicación.
Authors: Guzmán Esquivel José 
Published: February 2022

El tiempo actual apresura los pasos, corre contra el tiempo y deja en el camino la parsimonia y la calma que tiene la observación.Las revistas médicas, por su parte, han tenido cambios de la misma forma: acelerada y en constante movimiento, porque así lo marcan los tiempos y quien no se adapta o no se mueve, queda rezagado, dejado y olvidado.Parte de este editorial está basado en el reporte publicado en 2015 por la Asociación Internacional de Editores Científicos, Técnicos y Médicos (STM), que se refiere a una gran variedad de conceptos y al análisis de reportes de informes relacionados con la publicación.
Malacoplaquia vesical y uracal que simula un adenocarcinoma vesical
Authors: Martinez Salas Alan de Jesus , Jimenez Garcia Aldo Daniel , Muruato Araiza Jesus Sebastian , Reyna Blanco Irving , Gomez Sanchez Jose , Herrera Muñoz Javier , Preciado Estrella Diego Antonio , Martinez Arroyo Carlos , Fernandez Noyola Gerardo , Morales Montor Jorge Gustavo , Cantellano Orozco Mauricio , Pacheco Gahbler Carlos 
Published: February 2022

ANTECEDENTES: La malacoplaquia es una enfermedad relacionada con la actividad anormal de la función fagocitaria de los macrófagos, que suele afectar la vía urinaria y gastrointestinal, debido a infecciones crónicas (50%) o inmunosupresión (40%). CASO CLÍNICO: Paciente masculino de 44 años, que acudió al servicio de Urgencias por fiebre (39ºC) de 7 días de evolución, asociada con disuria y dolor abdominal infraumbilical, tipo cólico, intensidad 4/10, con masa periumbilical y leucocitosis. La urotomografía reportó defecto de llenado vesical y comunicación hacia la pared anterior abdominal. El tratamiento consistió en resección transuretral vesical; se resecó el tumor del domo y la pared anterior vesical, con salida de material mucoso. El paciente persistió con fiebre y dolor abdominal posoperatorio, por lo que se decidió efectuar una laparotomía exploradora, en la que se encontró una tumoración abdominal dependiente de la vejiga y el uraco, además de apendicitis reactiva. El reporte histopatológico fue malacoplaquia vesical y uracal. CONCLUSIÓN: Este el primer caso de malacoplaquia uracal con manifestación atípica reportado en el Hospital General Dr. Manuel Gea González. PALABRAS CLAVE: Malacoplaquia; vejiga; uraco.
Adenocarcinoma of the rete testis associated with castration-resistant prostate cancer
Authors: Cortez-Betancourt Roberto , Ramirez-Garduño Emilio , Alías-Melgar Alejandro , Carreño-De La Rosa Fernando , Botello-Gómez Pedro Jair , Trujillo-Vázquez Eric Iván , González-Serrano Adolfo 
Published: February 2022

BACKGROUND: Adenocarcinoma of the rete testis is a very rare diagnosis with only about 60 reported cases. To the best of our knowledge, the present report is the first on that tumor associated with prostate cancer. CLINICAL CASE: An 84-year-old man with a history of castration-resistant prostate cancer presented with a non-tender, solid, right testicular mass. Tumor markers were within normal limits. The patient underwent radical inguinal orchiectomy and the pathology study reported adenocarcinoma of the rete testis. Diagnosis was confirmed through immunohistochemistry and staining was positive for high molecular weight cytokeratin (CK HMW) and cytokeratin 5/6, and negative for PSA. CONCLUSION: Adenocarcinoma of the rete testis is a very rare condition. Clinical presentation of those tumors is nonspecific, and the diagnostic immunohistochemistry profile has not been well defined. Prognosis is poor, with a short overall survival rate. KEYWORDS: Adenocarcinoma; Immunohistochemistry; Orchiectomy; Rete testis; Testicular neoplasms