bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictors of non-response to successive waves of surveys in the Japan Environment and Children’s Study during the 3-year postpartum period: a longitudinal cohort study
Authors: Kigawa Mika , Tsuchida Akiko , Matsumura Kenta , Kasamatsu Haruka , Tanaka Tomomi , Hamazaki Kei , Adachi Yuichi , Inadera Hidekuni 
Published: July 2022

ObjectivesWe examined changes in factors related to non-response to successive waves of the nationwide birth cohort study, the Japan Environment and Children’s Study (JECS), during the first 3 years after childbirth.DesignLongitudinal cohort study.SettingAs the baseline survey, mothers completed self-administered questionnaires distributed by hand during pregnancy or 1 month after delivery. The self-administered questionnaires that we used in this study were then distributed by mail every 6 months until the children were 3 years old, for a total of six times.ParticipantsOf 103 060 mothers who consented to participate in the JECS during pregnancy, 88 489 mothers were included in the study after excluding those with multiple births, miscarriages or stillbirths and those who withdrew from the study within 3 years after providing informed consent.Primary and secondary outcome measuresData were collected at the baseline survey on participants’ socioeconomic status, medical history, health status, health-related behaviours and their children’s health conditions and living situations. The strength of the impact of related factors and the prediction of response status were examined and compared using binominal logistic regression analysis.ResultsFor all six follow-up questionnaire surveys, higher maternal age was strongly associated with providing a response. Factors that were strongly associated with mothers not providing a response were smoking after childbirth and having more children. The concordance rate of response status based on the presented model was about 70%, suggesting that the response status for the first 3 years after birth can be predicted from the information collected in the baseline survey.ConclusionBy identifying predictors of non-response from information obtained in baseline surveys, researchers may be able to reduce non-response to successive survey waves by issuing reminders, reviewing data collection methods and providing appropriate financial and/or non-financial incentives.
Revalidation and adaptation of the Menstrual Practice Needs Scale (MPNS) in a cross-sectional survey to measure the menstrual experiences of adult women working in Mukono District, Uganda
Authors: Hennegan Julie , Bukenya Justine N , Kibira Simon P S , Nakamya Petranilla , Makumbi Fredrick E , Exum Natalie G , Schwab Kellogg J 
Published: July 2022

ObjectivesThe Menstrual Practice Needs Scale (MPNS) is a comprehensive measure of menstrual self-care experience including access to sufficient, comfortable materials to catch or absorb bleeding, supportive spaces for managing menstruation and for disposal and laundering of used materials. It addresses a critical measurement gap to improve quantitative menstrual health research and programme evaluation. The scale was validated in a population of adolescent schoolgirls. This study appraises its performance among adult women.DesignCross-sectional survey.Setting and participantsSeven cognitive interviews provided insights into the interpretability of scale items. A survey of 525 working women who had menstruated in the past 6 months (435 working in markets, 45 in schools and 45 working in healthcare facilities) in Mukono District, Uganda was used to test the dimensionality, reliability and validity of the measure.ResultsThe 36 scale items were well understood by the study population. Dimensionality was tested for the 28 items relevant to women disposing of menstrual materials and 32 items relevant to those washing and reusing materials. The original subscale structure fit with the data, however, fell short of recommended thresholds for those disposing of materials (root mean squared error of approximation, RMSEA=0.069; Comparative Fit Index, CFI=0.840; Trucker-Lewis Index, TLI=0.824). An alternative subscale structure was an acceptable fit for those disposing (RMSEA=0.051; CFI=0.911; TLI=0.897) and reusing materials (RMSEA=0.053; CFI=0.915; TLI=0.904). MPNS total and subscale scores demonstrated acceptable internal consistency. Higher scores reflected more positive menstrual experiences and were associated with well-being (total score r=0.24, p<0.001), not missing work due to the last menstrual period (total score OR=2.47 95% CI 1.42 to 4.30) and confidence to manage menstruation.ConclusionsThe MPNS offers a valid and reliable way to assess menstrual health needs. The revised factor structure can be used for samples of adult workers. Findings also highlight challenges in assessing the variety of experiences relevant to managing menstrual bleeding.
Occupational outcomes of people with multiple sclerosis: a scoping review
Authors: Vitturi Bruno Kusznir , Rahmani Alborz , Dini Guglielmo , Montecucco Alfredo , Debarbieri Nicoletta , Sbragia Elvira , Bandiera Paolo , Ponzio Michela , Battaglia Mario Alberto , Manacorda Tommaso , Persechino Benedetta , Buresti Giuliana , Inglese Matilde , Durando Paolo 
Published: July 2022

ObjectivesTo update the knowledge on the occupational outcomes associated with multiple sclerosis (MS), systematically examine the extent, scope and nature of the pre-existing literature and identify research gaps in the existing literature.DesignScoping review.Data sourcesA comprehensive database search of PubMed/MEDLINE, Scopus, SciVerse ScienceDirect and Web of Science was performed. There were no time limits.Eligibility criteriaWe included any peer-reviewed original article reporting the occupational outcomes of people with MS between the ages of 18 and 65 years. We excluded those off-topic and with insufficient information.MethodsThis review was conducted following the Joanna Briggs Institute recommendations and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for scoping review checklist. Screening, reading of full-texts and data extraction was performed in a standardised way by expert reviewers from 14 July 2021 to 31 October 2021. We provided a narrative synthesis and an overview of findings.ResultsThe initial systematic search yielded 104 228 results. After removing duplicates and applying the exclusion criteria, 403 articles were included in the review. In total, the studies evaluated 492 062 subjects with MS. One hundred fifty-four (38.2%) articles were published in the last 5 years, mostly from Europe and North America (50.9% and 33.0%, respectively). Concerning the occupational outcomes, studies mostly addressed unemployment (311, 77.2%), early retirement (120, 29.8%), disability pension (117, 29.0%), sick leave (77, 19.1%), the indirect cost of MS (74, 18.4%) and work characteristics (57, 14.1%). The results were categorised into seven subtopics: ‘Changes in work and occupational status due to MS’, ‘work-related socio-economic consequences of MS’, ‘risk factors for unfavourable occupational outcomes’, ‘reported barriers to employment’, ‘reported job accommodations and vocational rehabilitation strategies’, ‘job satisfaction, stigma, and disclosing the diagnosis in the workplace’ and ‘rating clinical scales’.ConclusionsThere are several issues that deserve further in-depth study by the scientific community in order to improve the occupational outcomes of people with MS.
Ethical challenges in palliative sedation of adults: protocol for a systematic review of current clinical practice guidelines
Authors: Tomczyk Martyna , Jaques Cécile , Jox Ralf J 
Published: July 2022

IntroductionThis study aims to identify the full spectrum of ethical challenges of all forms of palliative sedation for adults as presented in current clinical practice guidelines (CPGs) and to determine whether CPGs specify ethical challenges of this therapy for patients with cancer and non-cancer and, if so, how exactly they do this. To the best of our knowledge, no studies have yet investigated this topic. The purpose is purely descriptive; our aim is not to make any kind of normative judgements on these challenges. Nor is our aim to assess the quality of the CPGs.Methods and analysisWe will perform a systematic review of CPGs on palliative sedation for adults via five electronic databases, grey literature search tools, citation tracking and contact with palliative care experts. Current CPGs accredited by an international, national or regional authority, published in English, German, French, Italian or Polish, from 2000 to the date of the search, will be subjected to content analysis at the textual, linguistic and thematic levels.Ethics and disseminationThis is a protocol for a systematic review and no human will be involved in this research. Therefore, ethics approval and consent to participate are not applicable to this context. This study protocol is reported in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis for Protocols criteria and registered on PROSPERO. Moreover, the integral version of this study protocol is published as a preprint on Research Square. The results of this study will be actively disseminated through peer-reviewed journals and books, international, national and local conference presentations, social media and media in general.
Computerised cognitive training tools and online nutritional group counselling for people with mild cognitive impairment: study protocol of a completely digital, randomised, controlled trial
Authors: Scheerbaum Petra , Book Stephanie , Jank Michael , Hanslian Etienne , DellO’ro Melanie , Schneider Julia , Scheuermann Julia-Sophia , Bösl Sophia , Jeitler Michael , Kessler Christian , Graessel Elmar 
Published: July 2022

IntroductionPeople with mild cognitive impairment (MCI) are at increased risk of decreasing cognitive functioning. Computerised cognitive training (CCT) and nutrition have been shown to improve the cognitive capacities of people with MCI. For each variable, we developed two kinds of interventions specialised for people with MCI (CCT: ‘individualised’ CCT; nutrition: a whole-food, plant-based diet). Additionally, there are two kinds of active control measures (CCT: ‘basic’ CCT; nutrition: a healthy diet following the current guidelines of the German Nutrition Society). The aim of this study is to investigate the effects of the two interventions on cognition in people with MCI in a 2×2 randomised controlled trial with German participants.Methods and analysisParticipants will be community-dwelling individuals with a psychometric diagnosis of MCI based on the Montreal Cognitive Assessment (MoCA) and Mini-Mental State Examination. With N=200, effects with an effect size off≥0.24 (comparable to Cohen’sd≥0.48) can be detected. Screening, baseline, t6 and t12 testing will be conducted via a videoconferencing assessment, telephone, and online survey. Participants will be randomly allocated to one of four groups and will receive a combination of CCT and online nutritional counselling. The CCT can be carried out independently at home on a computer, laptop, or tablet. Nutrition counselling includes 12 online group sessions every fortnight for 1.5 hours. The treatment phase is 6 months with follow-ups after six and 12 months after baseline.Ethics and disseminationAll procedures were approved by the Friedrich-Alexander-Universität Erlangen-Nürnberg Ethics Committee (Ref. 21-318-1-B). Written informed consent will be obtained from all participants. Results will be published in peer-reviewed scientific journals, conference presentations.Trial registration numberISRCTN10560738.
Can primary care research be conducted more efficiently using routinely reported practice-level data: a cluster randomised controlled trial conducted in England?
Authors: Blair Peter S , Ingram Jenny , Clement Clare , Young Grace , Seume Penny , Taylor Jodi , Cabral Christie , Lucas Patricia Jane , Beech Elizabeth , Horwood Jeremy , Dixon Padraig , Gulliford Martin C , Francis Nick , Creavin Sam T , Lane Athene , Bevan Scott , Hay Alastair D 
Published: July 2022

ObjectivesConducting randomised controlled trials (RCTs) in primary care is challenging; recruiting patients during time-limited or remote consultations can increase selection bias and physical access to patients’ notes is costly and time-consuming. We investigated barriers and facilitators to running a more efficient design.DesignAn RCT aiming to reduce antibiotic prescribing among children presenting with acute cough and a respiratory tract infection (RTI) with a clinician-focused intervention, embedded at the practice level. By using aggregate level, routinely collected data for the coprimary outcomes, we removed the need to recruit individual participants.SettingPrimary care.ParticipantsBaseline data from general practitioner practices and interviews with individuals from Clinical Research Networks (CRNs) in England who helped recruit practices and Clinical Commission Groups (CCGs) who collected outcome data.InterventionThe intervention included: (1) explicit elicitation of parental concerns, (2) a prognostic algorithm to identify children at low risk of hospitalisation and (3) provision of a printout for carers including safety-netting advice.Coprimary outcomesFor 0–9 years old—(1) Dispensing data for amoxicillin and macrolide antibiotics and (2) hospital admission rate for RTI.ResultsWe recruited 294 of the intended 310 practices (95%) representing 336 496 registered 0–9 years old (5% of all 0–9 years old children). Included practices were slightly larger, had slightly lower baseline prescribing rates and were located in more deprived areas reflecting the national distribution. Engagement with CCGs and their understanding of their role in this research was variable. Engagement with CRNs and installation of the intervention was straight-forward although the impact of updates to practice IT systems and lack of familiarity required extended support in some practices. Data on the coprimary outcomes were almost 100%.ConclusionsThe infrastructure for trials at the practice level using routinely collected data for primary outcomes is viable in England and should be promoted for primary care research where appropriate.Trial registration numberISRCTN11405239.
Prevalence and determinants of persistent symptoms after infection with SARS-CoV-2: protocol for an observational cohort study (LongCOVID-study)
Authors: Mutubuki Elizabeth N , van der Maaden Tessa , Leung Ka Yin , Wong Albert , Tulen Anna D , de Bruijn Siméon , Haverman Lotte , Knoop Hans , Franz Eelco , van Hoek Albert Jan , van den Wijngaard Cees C 
Published: July 2022

IntroductionA substantial proportion of individuals infected with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), report persisting symptoms weeks and months following acute infection. Estimates on prevalence vary due to differences in study designs, populations, heterogeneity of symptoms and the way symptoms are measured. Common symptoms include fatigue, cognitive impairment and dyspnoea. However, knowledge regarding the nature and risk factors for developing persisting symptoms is still limited. Hence, in this study, we aim to determine the prevalence, severity, risk factors and impact on quality of life of persisting symptoms in the first year following acute SARS-CoV-2 infection.Methods and analysisThe LongCOVID-study is both a prospective and retrospective cohort study being conducted in the Netherlands, with a one year follow-up. Participants aged 5 years and above, with self-reported positive or negative tests for SARS-CoV-2 will be included in the study. The primary outcome is the prevalence and severity of persistent symptoms in participants that tested positive for SARS-CoV-2 compared with controls. Symptom severity will be assessed for fatigue (Checklist Individual Strength (CIS subscale fatigue severity)), pain (Rand-36/SF-36 subscale bodily pain), dyspnoea (Medical Research Council (mMRC)) and cognitive impairment (Cognitive Failure Questionnaire (CFQ)). Secondary outcomes include effect of vaccination prior to infection on persistent symptoms, loss of health-related quality of life (HRQoL) and risk factors for persisting symptoms following infection with SARS-CoV-2.Ethics and disseminationThe Utrecht Medical Ethics Committee (METC) declared in February 2021 that the Medical Research Involving Human Subjects Act (WMO) does not apply to this study (METC protocol number 21-124/C). Informed consent is required prior to participation in the study. Results of this study will be submitted for publication in a peer-reviewed journal.
Mitigating and managing COVID-19 conspiratorial beliefs
Authors: Dow Benjamin J , Wang Cynthia S , Whitson Jennifer A , Deng Yingli 
Published: July 2022

Background/AimBelief in COVID-19 related conspiracy theories is a widespread and consequential problem that healthcare leaders need to confront. In this article, we draw on insights from social psychology and organisational behaviour to offer evidence-based advice that healthcare leaders can use to reduce the spread of conspiratorial beliefs and ameliorate their negative effects, both during the current pandemic and beyond.ConclusionLeaders can effectively combat conspiratorial beliefs by intervening early and bolstering people’s sense of control. Leaders can also address some of the problematic behaviours that result from conspiratorial beliefs by introducing incentives and mandates (e.g., vaccine mandates). However, because of the limitations of incentives and mandates, we suggest that leaders complement these techniques with interventions that leverage the power of social norms and increase people’s connections to others.
Probing electronic decoherence with high-resolution attosecond photoelectron interferometry
Authors: Busto David , Laurell Hugo , Finkelstein-Shapiro Daniel , Alexandridi Christiana , Isinger Marcus , Nandi Saikat , Squibb Richard J. , Turconi Margherita , Zhong Shiyang , Arnold Cord L. , Feifel Raimund , Gisselbrecht Mathieu , Salières Pascal , Pullerits Tönu , Martín Fernando , Argenti Luca , L’Huillier Anne 
Published: July 2022

Abstract
Quantum coherence plays a fundamental role in the study and control of ultrafast dynamics in matter. In the case of photoionization, entanglement of the photoelectron with the ion is a well-known source of decoherence when only one of the particles is measured. Here, we investigate decoherence due to entanglement of the radial and angular degrees of freedom of the photoelectron. We study two-photon ionization via the 2s2p autoionizing state in He using high spectral resolution photoelectron interferometry. Combining experiment and theory, we show that the strong dipole coupling of the 2s2p and 2p$$^2$$

2

states results in the entanglement of the angular and radial degrees of freedom. This translates, in angle-integrated measurements, into a dynamic loss of coherence during autoionization.

Graphic Abstract
The symplectic geometrical formulation of quantum hydrodynamics
Authors: Wijaya Andika Kusuma , Hermanto Arief , Rosyid Muhammad Farchani 
Published: July 2022

Quantum hydrodynamics described by Madelung equations is analyzed in the framework of symplectic geometry i.e. in covariant phase space approach to geometric field theory. The pre-symplectic manifolds providing the phase spaces describing the Hamiltonian dynamics of quantum fluid are constructed from the set of all solutions of Madelung equations and their corresponding Lagrangian densities. The Madelung equations under consideration are the Madelung equations associated to Schroedinger equations (in the nonrelativistic case) and Madelung equations associated to Klein–Gordon equations (in the relativistic case). The cases where the coupling with electromagnetic fields is present are also considered here. Our symplectic formulation is different from that of [M. Spera, Moment map and gauge geometric aspects of the Schrodinger and Pauli equations, Int. J. Geom. Methods Mod. Phys. 13 (2016) 1–36] in the choice of fundamental fields or variables. Here we regard density function [Formula: see text] and phase function [Formula: see text] not as canonical pair but as the fundamental fields of the theory. The Hamiltonian vector fields corresponding to an observable are obtained from the Hamiltonian equation generated by the observable. The Poisson bracket of two observables then is determined by the Hamiltonian vector fields associated to each observable. In general, the Poisson bracket of two observables is not unique due to the fact that every observable has more than one corresponding Hamiltonian vector field. It is pointed out that the Poisson bracket has a unique value over a certain subset of the set of all observables defined on the pre-symplectic manifold of the Madelung equation under consideration.
Mechanisms of COVID-19 pathogenesis in diabetes
Authors: Aluganti Narasimhulu Chandrakala , Singla Dinender K. 
Published: July 2022

Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, is a global pandemic impacting 254 million people in 190 countries. Comorbidities, particularly cardiovascular disease, diabetes, and hypertension, increase the risk of infection and poor outcomes. SARS-CoV-2 enters host cells through the angiotensin-converting enzyme-2 receptor, generating inflammation and cytokine storm, often resulting in multiorgan failure. The mechanisms and effects of COVID-19 on patients with high-risk diabetes are not yet completely understood. In this review, we discuss the variety of coronaviruses, structure of SARS-CoV-2, mutations in SARS-CoV-2 spike proteins, receptors associated with viral host entry, and disease progression. Furthermore, we focus on possible mechanisms of SARS-CoV-2 in diabetes, leading to inflammation and heart failure. Finally, we discuss existing therapeutic approaches, unanswered questions, and future directions. Listen to this article’s corresponding podcast at https://ajpheart.podbean.com/e/covid-19-and-diabetes/ .
Racial/Ethnic Disparities in Hepatocellular Carcinoma: The Role of Neighborhood Socioeconomic Deprivation
Authors: Lazo Mariana , Martinez-Folgar Kevin , Bilal Usama 
Published: July 2022

Abstract
The prevention of hepatocellular carcinoma (HCC) and reduction of its disparities necessitates research on the role of contextual social determinants of health. Empirical evidence on the role of contextual factors (e.g., neighborhood built and social environment) in these disparities is extremely limited. Oluyomi and colleagues conducted a Texas-wide study examining the contribution of neighborhood-level socioeconomic deprivation, proxied by the area deprivation index on HCC disparities. Future studies are needed to complement and extend these findings.
See related article by Oluyomi et al., p. 1402