bluuebunny/crossref_metadata_2025_split huggingface dataset:
Who shapes the CJEU regulatory jurisprudence? On the epistemic power of economic actors and ways to counter it
Authors: Morvillo Marta , Weimer Maria 
Published: November 2022

AbstractWhat role does the Court of Justice of the European Union (CJEU) play in holding European Union (EU) regulatory science, ie the science underpinning public regulation, to account for its epistemic quality? Since Pfizer, CJEU case law has strengthened the role of science in both EU risk regulation and litigation, whilst intensifying judicial scrutiny of scientific reasoning based on procedural standards. Scholars often welcome this approach as striking an adequate balance between effective judicial protection and institutional competence. Some praise the Court as an ‘information catalyst’ promoting procedures, in which epistemic quality is ensured through diligent consideration of and deliberation among all relevant voices. These debates, however, overlook the role of economic actors as information providers, in and challengers of EU risk regulation. This paper re-evaluates the modern post-Pfizer approach from a new, socio-legal perspective by studying, for the first time, the interactions between judicial review and the epistemic power of economic actors, ie their relative ability to influence what EU regulators know at the expense of other actors. We combine an epistemologically informed comparative institutional analysis with doctrinal critique of CJEU case law. Our findings show the need to rethink both legal standing and procedural review in EU risk regulation. Instead of catalysing inclusive procedures that open regulatory science to public scrutiny, the modern approach fosters an exclusive bilateral information exchange between the administration and the regulated industry. The Court reduces the function of process values, such as duty of care and reason-giving, to the protection of a small circle of actors, neglecting the public interest dimension of such values. Thus, the modern approach fails to address, and instead further entrenches the epistemic power imbalances inherent in EU risk regulation. We end by sketching out a normative and doctrinally sound vision of how CJEU review could contribute to EU expert accountability in a more publicly oriented way.
Posting of workers in the European Union: an exploitative labour system
Authors: Robin-Olivier Sophie 
Published: November 2022

AbstractThis article unpacks some severe forms of exploitation of workers, resulting from the use of free provision of services for purposes that it was not intended to fulfil, under internal market law. It explores how this evolution of posting relates to the existence of a market resting only on the international assignment of workers, and proposes that the European Union (EU) takes steps to limit or prohibit assignment of labour, especially in the sectors (agriculture, meat sector, construction) where posting of workers, as some recent cases show, leads to extreme forms of exploitation that can be tagged as slavery.
An ergodic system is dominant exactly when it has positive entropy
Authors: AUSTIN TIM , GLASNER ELI , THOUVENOT JEAN-PAUL , WEISS BENJAMIN 
Published: November 2022

AbstractAn ergodic dynamical system
$\mathbf {X}$
is called dominant if it is isomorphic to a generic extension of itself. It was shown by Glasner et al [On some generic classes of ergodic measure preserving transformations. Trans. Moscow Math. Soc.82(1) (2021), 15–36] that Bernoulli systems with finite entropy are dominant. In this work, we show first that every ergodic system with positive entropy is dominant, and then that if
$\mathbf {X}$
has zero entropy, then it is not dominant.
Effects of procalcitonin on antimicrobial treatment decisions in patients with coronavirus disease 2019 (COVID-19)
Authors: Conlon Anna S.C. , Chopra Zoey , Cahalan Shannon , Cinti Sandro , Rao Krishna 
Published: November 2022

AbstractObjective:To describe the natural course of procalcitonin (PCT) in patients with coronavirus disease 2019 (COVID-19) and the correlation between PCT and antimicrobial prescribing to provide insight into best practices for PCT data utilization in antimicrobial stewardship in this population.Design:Single-center, retrospective, observational study.Setting:Michigan Medicine.Patients:Inpatients aged ≥18 years hospitalized March 1, 2020, through October 31, 2021, who were positive for severe acute respiratory coronavirus virus 2 (SARS-CoV-2), with ≥1 PCT measurement. Exclusion criteria included antibiotics for nonpulmonary bacterial infection on admission, treatment with azithromycin only for chronic obstructive pulmonary disease (COPD) exacerbation, and pre-existing diagnosis of cystic fibrosis with positive respiratory cultures.Methods:A structured query was used to extract data. For patients started on antibiotics, bacterial pneumonia (bPNA) was determined through chart review. Multivariable models were used to assess associations of PCT level and bPNA with antimicrobial use.Results:Of 793 patients, 224 (28.2%) were initiated on antibiotics: 33 (14.7%) had proven or probable bPNA, 125 (55.8%) had possible bPNA, and 66 (29.5%) had no bPNA. Patients had a mean of 4.1 (SD, ±5.2) PCT measurements if receiving antibiotics versus a mean of 2.0 (SD, ±2.6) if not. Initial PCT level was highest for those with proven/probable bPNA and was associated with antibiotic initiation (odds ratio 95% confidence interval [CI], 1.17–1.30). Initial PCT (rate ratio [RR] 95% CI, 1.01–1.08), change in PCT over time (RR 95% CI, 1.01–1.05), and bPNA group (RR 95% CI, 1.23–1.84) were associated with antibiotic duration.Conclusions:PCT trends are associated with the decision to initiate antibiotics and duration of treatment, independent of bPNA status and comorbidities. Prospective studies are needed to determine whether PCT level can be used to safely make decisions regarding antibiotic treatment for COVID-19.
Two trichinellosis outbreaks in Serbia – challenging diagnosis due to a potential co-infection with Toxocara spp.
Authors: Mitic I. , Gnjatovic M. , Vasilev S. , Ristovic N. , Miladinovic-Tasic N. , Sofronic-Milosavljevic Lj. 
Published: November 2022

Abstract
In Serbia, in most cases, small family outbreaks of trichinellosis occur due to the consumption of untested infected meat from domestic pigs that are raised and slaughtered in the backyards of small individual farms. The aim of this study is to present data regarding 24 patients involved in two outbreaks that occurred in two neighbouring districts in Serbia during a closely related period of time in August 2014. The source of infection in the first outbreak was undercooked pork, while raw pork sausages caused the second outbreak. Meat samples and sausages were Trichinella spp. positive by artificial digestion. With the aim to obtain a second opinion and validate the serological findings discovered at the Public Health Institute Nis, all samples were sent to the National Reference Laboratory for Trichinellosis, INEP. Serodiagnosis showed that 21 persons were positive (87.5%) and three (12.5%) were negative for anti-Trichinella antibodies, while 15 patients fulfilled the trichinellosis case definition. Western blot analysis (using an epitope unique for the muscle larvae stage of the Trichinella genus) confirmed the diagnosis of trichinellosis in five patients. Six patients also had specific antibodies against Toxocara canis (T. canis). Due to the fact that in endemic foci in Serbia there is the presence of Trichinella spiralis and T. canis and that these two infections could be asymptomatic, we consider that trichinellosis cases were irrefutably proven. The dilemma about the existence of co-infection with T. canis remained open due to the lack of clinical findings.
Anaesthesia for non-cardiac surgery in children and young adults with Fontan physiology
Authors: Brown Morgan L. , Cradeur Michael , Staffa Steven J. , Nasr Viviane G. , Hernandez Michael R. , DiNardo James A. 
Published: November 2022

AbstractIntroduction:Patients with Fontan physiology require non-cardiac surgery. Our objectives were to characterise perioperative outcomes of patients with Fontan physiology undergoing non-cardiac surgery and to identify characteristics which predict discharge on the same day.Materials and Method:Children and young adults with Fontan physiology who underwent a non-cardiac surgery or an imaging study under anaesthesia between 2013 and 2019 at a single-centre academic children’s hospital were reviewed in a retrospective observational study. Continuous variables were compared using the Wilcoxon rank sum test, and categorical variables were analysed using the Chi-square test or Fisher’s exact test. Multivariable logistic regression analysis results are presented by adjusted odds ratios with 95% confidence intervals and p values.Results:182 patients underwent 344 non-cardiac procedures with anaesthesia. The median age was 11 years (IQR 5.2–18), 56.4% were male. General anaesthesia was administered in 289 (84%). 125 patients (36.3%) were discharged on the same day. On multivariable analysis, independent predictors that reduced the odds of same-day discharge included the chronic condition index (OR 0.91 per additional chronic condition, 95% CI 0.76–0.98, p = 0.022), undergoing a major surgical procedure (OR 0.17, 95% CI 0.05–0.64, p = 0.009), the use of intraoperative inotropes (OR 0.48, 95% CI 0.25–0.94, p = 0.031), and preoperative admission (OR = 0.24, 95% CI: 0.1–0.57, p = 0.001).Discussion:In a contemporary cohort of paediatric and young adults with Fontan physiology, 36.3% were able to be discharged on the same day of their non-cardiac procedure. Well selected patients with Fontan physiology can undergo anaesthesia without complications and be discharged same day.
Late diagnosis of CHD and its associated factors in Kenya: an analytic cross-sectional study
Authors: Ng’eno Mercy , Quadros Del-rossi S. , Gachara Naomi , Kihurani Isaac , Yonga Gerald 
Published: November 2022

AbstractIntroduction:Burden of CHD in Africa is generally underestimated mainly due to significant under-reporting and early-related fetal and neonatal mortality.Objectives:Determine the prevalence and factors associated with late diagnosis of CHD seen at three tertiary care hospitals in Kenya.Design:A cross-sectional study on paediatric patients with CHDs, aged 0–18 years, seen over a 5-year period, between January, 2011 and December, 2016.Setting:Aga Khan University Hospital Nairobi, Mater Hospital, and Kenyatta National Hospital.Methods:Patients were stratified into those diagnosed late (>1 year of age) and those diagnosed early (<1 year of age). Multiple logistic regression analysis was done to determine factors associated with late diagnosis.Results:The study enrolled 411 patients, with equal gender distribution. Prevalence of late diagnosis (>1 year of age) of CHD was 60.6% (95% CI 55.7–65.3). Median age at diagnosis was 15 (IQR 5–48) months. Presence of a cardiac murmur (OR = 0.87; 95% CI 0.72–0.92, p-value = 0.016) and level of parental education (OR = 4.99; 95% CI 2.25–11.40, p-value <0001) were associated with a decreased odds of late diagnosis. Other factors like cyanosis, an increase in the number of healthcare workers and healthcare facilities per 10,000 population showed some association with decreased odds of late diagnosis of CHD, but these were not statistically significant.Conclusion:Late diagnosis of CHD remains alarmingly high in our setting. Initiatives to enhance early detection and screening of CHD should be adopted to reduce related mortality and morbidity.
Senior food insecurity in the USA: a systematic literature review
Authors: Mavegam Tango Assoumou Bertille Octavie , Coughenour Courtney , Godbole Amruta , McDonough Ian 
Published: November 2022

AbstractObjective:Understanding the factors associated with senior food insecurity is key to understanding senior-specific needs to develop targeted interventions and ultimately lower the prevalence and the incidence of food insecurity. We aimed to systematically review published literature and summarise the associated factors of food insecurity in older adults in the USA.Design:We searched PubMed, Scopus, Web of science, EconLit and JSTOR databases for peer-reviewed articles published in English between January 2005 and September 2019 that assessed food security or its associated factors for US adults aged 60 years and older. After a two-step screening process, twenty articles were retained and included in the review.Setting:NAParticipants:NAResults:The majority of studies were cross-sectional (70 %), consisted of data from one state (60 %), and had large sample sizes. Food-insecure individuals were more likely to be younger, less educated, Black or African American, female, a current smoker, low income, and self-report fair/poor health, have chronic conditions, and utilise government assistance programmes. Food insecurity was associated with medication non-adherence, poor mental health outcomes and limitations in physical functioning. Results were mixed for overweight/obesity status. There was no discernable pattern related to the consistency of findings by the assessed quality of the included studies.Conclusions:Food insecurity is a prevalent and pervasive issue for older adults. The numerous correlates identified suggest that interventions aimed at enhancing food and nutrition safety net and medication assistance programmes are warranted, and upstream, systemic-level interventions may be best suited to deal with the correlates of food insecurity.
Unmasking the Effects of Aerosols on Greenhouse Warming Over Europe
Authors: Glantz P. , Fawole O. G. , Ström J. , Wild M. , Noone K. J. 
Published: November 2022

AbstractAerosol optical thickness (AOT) has decreased substantially in Europe in the summer half year (April–September) since 1980, with almost a 50% reduction in Central and Eastern Europe, according to Modern‐Era Retrospective analysis for Research and Applications, Version 2 (MERRA‐2) reanalysis. At the same time, strong positive trends in ERA5 reanalysis surface solar radiation downward for all‐sky and clear‐sky conditions (SSRD and SSRDc, respectively) and temperature at 2 m are found for Europe in summer during the period 1979–2020. The GEBA observations show as well strong increases in SSRD during the latest four decades. Estimations of changes in SSRDc, using the Santa Barbara DISORT Atmospheric Radiative Transfer (SBDART) model, show similarly strong increases when fed by MERRA‐2 AOT. The estimates of warming in this study, caused by increases in SSRD and SSRDc, are based on energy budget approximations and the Stefan Boltzmann law. The increases in near surface temperature, estimated both for clear‐sky and all‐sky conditions, are up to about 1°C for Central and Eastern Europe. The total warming over large parts of this region for clear‐sky conditions is however nearly double the global mean temperature increase of 1.1°C, while somewhat less for all‐sky conditions. The effects of aerosols on warming over the southerly Iberian Peninsula are weaker compared to countries further north. The rapid total warming over the Iberian Peninsula is probably caused by greenhouse warming, drier surface conditions, and to some degree decline in aerosols. Reduced cloud cover is found for large parts of Europe in summer during the latest four decades.
The Climatic Impact‐Driver Framework for Assessment of Risk‐Relevant Climate Information
Authors: Ruane Alex C. , Vautard Robert , Ranasinghe Roshanka , Sillmann Jana , Coppola Erika , Arnell Nigel , Cruz Faye Abigail , Dessai Suraje , Iles Carley E. , Islam A. K. M. Saiful , Jones Richard G. , Rahimi Mohammad , Carrascal Daniel Ruiz , Seneviratne Sonia I. , Servonnat Jérôme , Sörensson Anna A. , Sylla Mouhamadou Bamba , Tebaldi Claudia , Wang Wen , Zaaboul Rashyd 
Published: November 2022

AbstractThe climate science and applications communities need a broad and demand‐driven concept to assess physical climate conditions that are relevant for impacts on human and natural systems. Here, we augment the description of the “climatic impact‐driver” (CID) approach adopted in the Working Group I (WGI) contribution to the Intergovernmental Panel on Climate Change (IPCC) Sixth Assessment Report. CIDs are broadly defined as “physical climate system conditions (e.g., means, events, and extremes) that affect an element of society or ecosystems. Depending on system tolerance, CIDs and their changes can be detrimental, beneficial, neutral, or a mixture of each across interacting system elements and regions.” We give background information on the IPCC Report process that led to the development of the 7 CID types (heat and cold, wet and dry, wind, snow and ice, coastal, open ocean, and other) and 33 distinct CID categories, each of which may be evaluated using a variety of CID indices. This inventory of CIDs was co‐developed with WGII to provide a useful collaboration point between physical climate scientists and impacts/risk experts to assess the specific climatic phenomena driving sectoral responses and identify relevant CID indices within each sector. The CID Framework ensures that a comprehensive set of climatic conditions informs adaptation planning and risk management and may also help prioritize improvements in modeling sectoral dynamics that depend on climatic conditions. CIDs contribute to climate services by increasing coherence and neutrality when identifying and communicating relevant findings from physical climate research to risk assessment and planning activities.
Hyperspectral Reflectance for Measuring Canopy‐Level Nutrients and Photosynthesis in a Salt Marsh
Authors: Vázquez‐Lule Alma , Seyfferth Angelia L. , Limmer Matt A. , Mey Paul , Guevara Mario , Vargas Rodrigo 
Published: November 2022

AbstractSalt marsh ecosystems are underrepresented in process‐based models due to their unique location across the terrestrial–aquatic interface. Particularly, the role of leaf nutrients on canopy photosynthesis (FA) remains unclear, despite their relevance for regulating vegetation growth. We combined multiyear information of canopy‐level nutrients and eddy covariance measurements with canopy surface hyperspectral remote sensing (CSHRS) to quantify the spatial and temporal variability of FA in a temperate salt marsh. We found that FA showed a positive relationship with canopy‐level N at the ecosystem scale and for areas dominated by Spartina cynosuroides, but not for areas dominated by short S. alterniflora. FA showed a positive relationship with canopy‐level P, K, and Na, but a negative relationship with Fe, for areas associated with S. cynosuroides, S. alterniflora, and at the ecosystem scale. We used partial least squares regression (PLSR) with CSHRS and found statistically significant data–model agreements to predict canopy‐level nutrients and FA. The red‐edge electromagnetic region and ∼770 nm showed the highest contribution of variance in PLSR models for canopy‐level nutrients and FA, but we propose that underlying sediment biogeochemistry can complicate interpretation of reflectance measurements. Our findings highlight the relevance of spatial variability in salt marshes vegetation and the promising application of CSHRS for linking information of canopy‐level nutrients with FA. We call for further development of canopy surface hyperspectral methods and analyses across salt marshes to improve our understanding of how these ecosystems will respond to global environmental change.
A Swin Transformer-based model for mosquito species identification
Authors: Zhao De-zhong , Wang Xin-kai , Zhao Teng , Li Hu , Xing Dan , Gao He-ting , Song Fan , Chen Guo-hua , Li Chun-xiao 
Published: November 2022

AbstractMosquito transmit numbers of parasites and pathogens resulting in fatal diseases. Species identification is a prerequisite for effective mosquito control. Existing morphological and molecular classification methods have evitable disadvantages. Here we introduced Deep learning techniques for mosquito species identification. A balanced, high-definition mosquito dataset with 9900 original images covering 17 species was constructed. After three rounds of screening and adjustment-testing (first round among 3 convolutional neural networks and 3 Transformer models, second round among 3 Swin Transformer variants, and third round between 2 images sizes), we proposed the first Swin Transformer-based mosquito species identification model (Swin MSI) with 99.04% accuracy and 99.16% F1-score. By visualizing the identification process, the morphological keys used in Swin MSI were similar but not the same as those used by humans. Swin MSI realized 100% subspecies-level identification inCulex pipiensComplex and 96.26% accuracy for novel species categorization. It presents a promising approach for mosquito identification and mosquito borne diseases control.
Prevalence of cerebrovascular accidents in patients with ulcerative colitis in a single academic health system
Authors: Horta Erika , Burke-Smith Conor , Megna Bryant W. , Nichols Kendall J. , Vaughn Byron P. , Reshi Rwoof , Shmidt Eugenia 
Published: November 2022

AbstractIn general, IBD increases arteriovenous thromboembolic events, though the association between UC and cerebrovascular complications remains inconclusive. Some studies suggest young women with UC have an increased risk of cerebrovascular accidents (CVA). The focus of this study was to characterize the rates, anatomic distribution, and risk factors for CVA in patients with UC. We developed a retrospective cohort of patients with UC at a single health care system from June 2010 to June 2015. Neuroimaging was used to document presence, location and type of stroke and traditional risk factors were considered. Prevalence of CVAs in patients with UC was compared to that of the general population of Minnesota (MN) and the United States (U.S.). A total of 2,183 UC patients were identified (1088 females [f-UC], 1095 males [m-UC]). The prevalence of CVA in UC patients (4.7%, 95% CI 3.9–5.6) was higher than in the U.S. (2.5–2.7%, p < 0.0001) and in Minnesota (1.8% CI 1.5–2.2, p < 0.0001) . The prevalence increased in both sexes with a peak prevalence of 24.7% (95% CI 17.1–34.4) in women with UC over the age of 80. Older age, cancer and atrial fibrillation were risk factors for CVA in univariate analysis for both sexes. In multifactorial analysis, both age and atrial fibrillation were risk factors for CVA in the m-UC cohort, but only age was associated with CVA in f-UC. The most common type of CVA was ischemic stroke (77.7%). The most common locations for CVAs in UC patients were frontal and occipital lobes (19% and 18%, respectively). UC patients have an increased risk for CVA, with women over 80 demonstrating the highest risk. Providers should be aware of these risks in making treatment decisions for UC.