bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flexible human resource management systems and employee innovation performance in China – based on the moderated mediation effect
Authors: Xu Yan , Qian Han , Zhang Min , Tian Feng , Zhou Lulu , Zhao Shuming 
Published: November 2022

Purpose
This paper aims to explore the impact of flexible human resource management system (FHRMS) on employee innovation performance in Chinese context. The boundary conditions of employability and organizational identity are also discussed.

Design/methodology/approach
This study is based on 322 questionnaire survey from employees in China. The questionnaires were collected at two time points. This study used the method of multi-level linear model analysis for empirical test.

Findings
This study has three conclusions. First, FHRMS have a significant positive impact on employee innovation performance, with employability playing a mediating role. Second, organizational identity plays a moderating role between employability and employee innovation performance. Third, organizational identity moderates the mediating effect of a human source management systems on employee innovation performance through employability.

Originality/value
The results are helpful to open the “black box” of the influence of FHRMS on employees’ individual innovation performance. This study provides a reference for enterprises to establish flexible human source management system to improve employee innovation performance.
Organizational learning via gamification for employer brand management
Authors: Kaoud Menatalla , ElBolok Mostafa 
Published: November 2022

Purpose
This paper aims to deepen our understanding of how serious games could be used for learning in organizations to empower brand performance and image sustaining competitive advantage from a Resource Based View (RBV) perspective and to examine the practical implications of the evolving technologies for employers.

Design/methodology/approach
The research methodology is based on a qualitative approach adopting the case study research method (Yin, 2003). Data were collected through fifteen semi-structured interviews (a total of twelve hours) with the involved departments (particularly, Human Resource Management and Marketing) and one month of direct observation for their learning and communication approaches.

Findings
Serious games can encourage the learning of employees enhancing their skills and brand performance. Besides, Customer Relationship Management (CRM) tools, a knowledge base, and social media platforms can help in promoting favorable employer brand knowledge, which positively influences the brand image and awareness.

Practical implications
From a RBV perspective, businesses can develop their employer branding practices through engaging ways of learning and brand knowledge management supported by digital tools along with boundary-less workplaces, communication efforts, and change management enabling them to enhance brand performance and sustain a competitive advantage.

Originality/value
The evidence on marketing knowledge management is still limited. This case study research makes an empirical contribution by analyzing how serious games and digital technologies could foster the learning in organizations for building strong employer brand knowledge. It answers the call for providing more insights on the relationship between knowledge management and employer brand management.
Dozee: crafting opportunities during the COVID-19 pandemic [1]
Authors: Kerai Anita , George Nycil 
Published: November 2022

Research methodology
This case was developed from secondary sources. The secondary sources included company websites, social media and news reports. This case has been classroom tested in multiple executive master of business administration (MBA) courses on business model innovation and entrepreneurship.

Case overview/synopsis
The case traces the entrepreneurial journey of Dozee, a remote patient monitoring system in India. Dozee was manufactured by Turtle Shell Technologies Private Limited, cofounded by Mudit and Gaurav. The primary customers of Dozee’s offering were households with elderly citizens and health-conscious individuals who sought preventive health care. The cofounders identified the unmet need for a convenient and user-friendly contactless health tracker. Dozee team built a thin sensor-embedded sheet and module that can be placed beneath the mattress to track sleep patterns and health vitals. They also provided data analysis and data interpretation services. After four years of conceptualization, Dozee launched its product and service in 2019. Although the initial response was lukewarm, the onset of the COVID-19 crisis led to significant changes in the health-care industry. Demand for virtual assistance and contactless monitoring devices became increasingly important elements of COVID-19 treatment. Unlike other sensor-based fitness trackers, the sheet could be easily placed under the patient’s bed to capture health vitals. Choosing to pivot from a home-based individual customer segment to a medical-grade device provider for hospitals could significantly increase the scale and scope of the offering for Dozee, but it would also place Dozee in direct competition with other health monitoring devices from different business categories.

Complexity academic level
This case is appropriate for MBA and executive-level courses related to entrepreneurship and business model innovation. The case explores issues such as digital disruption and how start-ups can design a go-to-market strategy. The case works well in the classroom, even if people are unfamiliar with the health-care industry. Participants can certainly relate to the concept of adopting artificial intelligence–enabled devices for monitoring their health. The instructor should be able to quickly engage participants in a lively discussion about Dozee’s vision and the opportunities and challenges in adopting digital solutions in health care.
Green hotel selection: the effects of social learning and eco-labels
Authors: Baniya Rojan , An Yuting , Thapa Brijesh 
Published: November 2022

PurposeSustainable consumption is a crucial route to sustainable tourism. Hence, the purpose of this study is to investigate the individual and combined effect of social learning and eco-labels on the green hotel selection.Design/methodology/approachThis study used a between-subject online experimental method with 199 respondents, which is used only in around 15% of published tourism articles. Additionally, this method provided reliability and control features.FindingsSocial learning and eco-labels individually could not influence tourists to select green hotels. However, the interaction of positive performance social learning with eco-labels could potentially influence tourists' green hotel selection. Therefore, internalizing green hotel performance from trusted sources and external validation bring behavioral changes among tourists to select green hotels. This study offers a new social learning-based model for understanding sustainable consumption.Research limitations/implicationsThis study can use various other types of social influences and can be expanded to other green settings.Practical implicationsThis study provides policy and promotion formulation insights to hotel managers and sustainable tourism promoters to market green hotels.Originality/valueAway from the traditional theory, this study bridges the gap between social learning of performance from relatable sources, assurance from governing entities and sustainable consumption. The interaction effect of social influence and eco-label on green hotel selection is a novel finding. Also, this study introduces various levels of social learning to the discussion of sustainable consumption.
Effects of vitamin D on inflammatory state in patients with chronic kidney disease: A controversial issue
Authors: Zhao Liangbin , Zhu Guoshuang , Wu Ling , Xie Dengpiao 
Published: November 2022

AbstractBackgroundThe anti‐inflammatory effect of vitamin D in patients with chronic kidney disease (CKD) remains controversial. This study aimed to conduct a meta‐analysis of randomized controlled trials to assess the anti‐inflammatory effects of vitamin D in patients with CKD.MethodsWe searched Embase, Science Citation Index, Medline, Cochrane Central Register of Controlled Trials, and Clinical Trial Registries for randomized controlled trials that comparing vitamin D with control groups for inflammatory markers in patients with CKD. Subgroup analysis was performed based on treatment duration (short‐term treatment, long‐term treatment), type of patients (predialysis CKD, dialysis, kidney transplant), 25(OH)D levels (25(OH)D deficiency or normal 25(OH)D), and methods of C‐reactive protein (CRP) test (standard CRP test or high‐sensitivity CRP [hs‐CRP] test).ResultsEighteen trials with 1834 patients were included in the present study. There were no significant differences between the vitamin D group and control group for CRP (WMD, −0.3 mg/L; 95% CI, −0.81 to 0.22, p = 0.26, I2 = 62%), interleukin‐6 (IL‐6) (WMD, −1.07 pg/ml; 95% CI, −2.44 to 0.30, p = 0.12, I2 = 52%), and tumor necrosis factor‐α (TNF‐α) (WMD, −0.00 pg/ml; 95% CI, −0.36 to 0.35, p = 0.99, I2 = 0%) in patients with CKD. Subgroup analysis showed vitamin D can improve hs‐CRP, but not CRP. The rest of subgroups showed that no significant differences were observed between the vitamin D group and control group based on 25(OH)D levels, treatment duration, and predialysis CKD or dialysis patients.ConclusionThis meta‐analysis demonstrates that vitamin D supplementation does not have anti‐inflammatory effects in CKD patients. Well‐designed randomized controlled trials with large samples are required to confirm this conclusion. It is still needed to find an effective treatment for inflammatory state in CKD.
Sleep‐disordered breathing in children seeking orthodontic care—an Australian perspective
Authors: Wellham A , Kim C , Kwok SS , Lee RJH , Naoum S , Razza JM , Goonewardene MS 
Published: November 2022

AbstractBackgroundThe prevalence of sleep‐disordered breathing in children is underestimated due to impediments in detection and diagnosis. Consequently, delayed management may affect the quality of life and the growth and development of a child. Due to their patient demographic, orthodontists are optimally positioned to identify those at risk of sleep‐disordered breathing and make referrals for investigation and management. This study aims to determine the prevalence of children at risk of sleep‐disordered breathing in an Australian orthodontic population.MethodsA 1‐year retrospective study was conducted in an urban Western Australian private orthodontic practice with two branches in similar socioeconomic demographics. The responses of new patients to a modified paediatric sleep questionnaire and standard medical history form were recorded.ResultsIn 1209 patients (4–18 years), 7.3% were at risk of sleep‐disordered breathing. An association between sex and the potential risk of sleep‐disordered breathing was found with 11% of males at risk of sleep‐disordered breathing compared to 7% of females (P = 0.012).ConclusionsThe relatively high prevalence of children at risk of sleep‐disordered breathing presenting for orthodontic care presents an opportunity to identify at‐risk individuals through routine use of the paediatric sleep questionnaire. This would facilitate early referral for diagnosis and management of sleep‐disordered breathing.
The diagnostic role of T wave morphology biomarkers in congenital and acquired long QT syndrome: A systematic review
Authors: Tardo Daniel T. , Peck Matthew , Subbiah Rajesh N. , Vandenberg Jamie I. , Hill Adam. P. 
Published: November 2022

AbstractIntroductionQTc prolongation is key in diagnosing long QT syndrome (LQTS), however 25%–50% with congenital LQTS (cLQTS) demonstrate a normal resting QTc. T wave morphology (TWM) can distinguish cLQTS subtypes but its role in acquired LQTS (aLQTS) is unclear.MethodsElectronic databases were searched using the terms “LQTS,” “long QT syndrome,” “QTc prolongation,” “prolonged QT,” and “T wave,” “T wave morphology,” “T wave pattern,” “T wave biomarkers.” Whole text articles assessing TWM, independent of QTc, were included.ResultsSeventeen studies met criteria. TWM measurements included T‐wave amplitude, duration, magnitude, Tpeak‐Tend, QTpeak, left and right slope, center of gravity (COG), sigmoidal and polynomial classifiers, repolarizing integral, morphology combination score (MCS) and principal component analysis (PCA); and vectorcardiographic biomarkers. cLQTS were distinguished from controls by sigmoidal and polynomial classifiers, MCS, QTpeak, Tpeak‐Tend, left slope; and COG x axis. MCS detected aLQTS more significantly than QTc. Flatness, asymmetry and notching, J‐Tpeak; and Tpeak‐Tend correlated with QTc in aLQTS. Multichannel block in aLQTS was identified by early repolarization (ERD30%) and late repolarization (LRD30%), with ERD reflecting hERG‐specific blockade. Cardiac events were predicted in cLQTS by T wave flatness, notching, and inversion in leads II and V5, left slope in lead V6; and COG last 25% in lead I. T wave right slope in lead I and T‐roundness achieved this in aLQTS.ConclusionNumerous TWM biomarkers which supplement QTc assessment were identified. Their diagnostic capabilities include differentiation of genotypes, identification of concealed LQTS, differentiating aLQTS from cLQTS; and determining multichannel versus hERG channel blockade.
Any Labour Geographies in Urban Theory? Workers Meet Lefebvre and Harvey (Yet Again)
Authors: Hayashi Mahito 
Published: November 2022

AbstractThis paper examines the urban theory of Henri Lefebvre and David Harvey to construct anurbanperspective on labour geographies. Lefebvre understood work in a work–nonwork continuum beyond binarism, and Lefebvre and Harvey hailed the outpouring of working‐class agency from cities. However, they may have obscured the role of labour movements in urbanisation when identifying the living‐place (such as streets, neighbourhoods, or housing) as the primary seat of urban agency. Learning from labour geographers in the 1990s, I query this ambiguity to enhance the urban theory of Lefebvre and Harvey, conceive of the urban scale as the site ofunfinishedindustrial/urban dialectics, and conceptualise labour agency as a producer of transformative continua in urbanisation. Interpreting Toyota’s factories as rescaled pivots of industrial urbanisation, I explore how Japanese labour movements challenged just‐in‐time production, its union form, and its work/nonwork divides, producing new urbanising continua—even planetary ones—between different transformative agencies.
Impact of intravitreal ranibizumab, aflibercept and bevacizumab on retinal ganglion cell and nerve fibre layer thickness in Neovascular age‐related macular degeneration
Authors: Abu Dail Yaser , Seitz Berthold , Sideroudi Haris , Abdin Alaa D. 
Published: November 2022

AbstractPurposeTo compare the effects of monotherapy with intravitreal ranibizumab, aflibercept and bevacizumab on retinal ganglion cell layer (RGCL) and retinal nerve fibre layer (RNFL) in patients with naïve neovascular age‐related macular degeneration (nAMD).MethodsThis is a retrospective cohort study with three‐groups comparison. 83 patients and 97 eyes on continuous monotherapy with an intravitreal anti‐vascular endothelial growth factor (anti‐VEGF) were followed for 24 months and divided into three groups according to anti‐VEGF (aflibercept: 25 eyes, ranibizumab: 34 eyes, bevacizumab: 38 eyes). Main outcome measures included: RGCL and RNFL thickness, best corrected visual acuity (BCVA), central macular thickness (CMT), macular volume (MV) and the presence of intraretinal fluids (IRF), subretinal fluids (SRF) and retinal pigment epithelial atrophy (RPE‐atrophy). All outcome measures were recorded at the time of the first injection, 1 and 2 years after treatment and compared longitudinally and between groups.ResultsThe mean age was 79 ± 7 years. The RGCL thickness, MV, CMT and the presence of IRF and SRF decreased significantly within all three medication groups (p < 0.05 for all) with no significant difference between groups over the 2‐year follow‐up period (p > 0.10 for all). The decrease in RNFL thickness was not significant within or between the groups after a 2‐year follow‐up (p > 0.055 for all). RPE‐atrophy increased significantly after 2 years in all three groups (p < 0.028 for all) with no significant difference between groups at all three time points (p > 0.307 for all). BCVA was comparable between the three groups over the 2‐year follow‐up period (p > 0.22 for all).ConclusionsMonotherapy with intravitreal aflibercept, bevacizumab and ranibizumab was associated with comparable significant decreases in RGCL thickness, CMT, MV, IRF and SRF in naïve nAMD patients during the first 2 years of treatment. Furthermore, no significant differences either in BCVA or RNFL thickness were observed between the three intravitreal anti‐VEFGs during the first 2 years of treatment.
Myeloperoxidase expression in diencephalon is potentially associated with fear‐related behavior in chicks of laying hen
Authors: Kohno Suzuka , Ogawa Shinichiro , Shimmura Tsuyoshi , Sato Kan , Tokutake Yukako 
Published: November 2022

AbstractPreventing feather pecking (FP) in adult laying hens is important for the welfare of intensively poultry farming. Fear‐related behavior in growing female layer chicks may predict FP in adult hens. In this study, in two representative laying breeds (White Leghorn [WL] and Rhode Island Red [RIR]) that have different FP frequencies, we identified a candidate gene associated with fear‐related behavior in chicks and FP in adult hens. In the tonic immobility test and open‐field test, the behavioral activity was lower in WL chicks than in RIR chicks (P < 0.01), suggesting that WL chicks were more fearful than RIR chicks. Based on previous studies, 51 genes that have been found to be differentially expressed in the brain between high‐ and low‐FP populations were chosen, and their expression levels were screened in the chick diencephalon. This analysis revealed that myeloperoxidase (MPO) gene expression level was higher in WL chicks than that in RIR chicks (P < 0.05). Furthermore, STRING analysis predicted the gene network including MPO and MPO‐related genes and revealed the association of these genes with fear‐related behavior. These results suggest that MPO is potentially associated with fear‐related behavior in growing female layer chicks and FP in adult hens.
Effects of ozonized glycerin on inflammation of mammary glands induced by intramammary lipopolysaccharide infusion in goats
Authors: Suzuki Naoki , Hirano Masato , Shinozuka Yasunori , Kawai Kazuhiro , Okamoto Yoshiharu , Isobe Naoki 
Published: November 2022

AbstractAlthough ozone shows antimicrobial activity against mastitis‐causing pathogens in ruminants, its anti‐inflammatory effect on mammary glands remains unclear. The aim of this study was to examine the anti‐inflammatory effects of ozonized glycerin (OG) on experimentally induced inflammation in the mammary glands of six Shiba and two Tokara lactating goats. We infused 1 μg lipopolysaccharide (LPS) into all udders on day −1. On day 0, post LPS infusion, OG (ozone group), and glycerin (control group) were infused into the right and left sides of the udders, respectively. Milk samples were collected once daily from days −1 to 7. The somatic cell count and lactoperoxidase (LPO) activity, along with the interleukin‐1β (IL‐1β), tumor necrosis factor‐α, IL‐8, IL‐10, lactoferrin, and sodium ion concentrations in milk were measured. IL‐8, IL‐10, and lactoferrin levels after LPS infusion in the ozone group were significantly lower than those in the control group, and the LPO activity tended to be lower than that observed in the control group. This study showed that OG has anti‐inflammatory potential against LPS‐induced inflammation in the mammary glands.
Evaluating the impact of thrombopoietin receptor agonist medications on patient outcomes and quality of life in paediatric immune thrombocytopenia through semi‐structured interviews
Authors: Livingston Joel , Alrajhi Ziyad , Jackson Melanie , McGuire Catherine , Newhook Dennis , Klaassen Robert J. , Kirby‐Allen Melanie 
Published: November 2022

SummaryOver the last decade, treatment of immune thrombocytopenia (ITP) in children has advanced to include thrombopoietin receptor agonist (TPO‐RA) medications. Concurrently, there has been an increased emphasis on patient‐reported outcomes—especially quality of life—to guide treatment. Assessing the impact of TPO‐RAs on quality of life in paediatric ITP is therefore a priority. In this single‐centre integrative mixed‐methods study, a cohort of children with ITP prescribed a TPO‐RA was identified. These children and/or their caregivers were invited to participate in semi‐structured interviews focussed on quality‐of‐life measures. Independently, a retrospective chart review collected ITP‐related data (platelet count, bleeding events) and TPO‐RA data (dosing, side effects). Among the 23 eligible patients, 20 were represented in interviews. On chart review, 11/20 patients responded to TPO‐RA by meeting platelet count criteria of ≥50 × 109/L for six or more weeks in the absence of rescue therapy. In interviews with these children and/or their parents, 19/20 expressed the TPO‐RA had ‘worked’, with 11/20 reporting benefit to mood and 11/20 reporting increased participation in activities/sports. Concerns were raised in interviews about TPO‐RA medication cost (17/20), medication administration (10/20) and potential side effects (10/20). In conclusion, this study suggests that TPO‐RA use in children with ITP improves quality of life.
Are plant communities on the Canary Islands resistant to plant invasion?
Authors: Fernández‐Palacios José María , Schrader Julian , de Nascimento Lea , Irl Severin D. H. , Sánchez‐Pinto Lázaro , Otto Rüdiger 
Published: November 2022

AbstractOceanic islands are renowned for their unique flora and high levels of endemism. Native island plants, however, are imperilled by non‐native species that can become invasive by outcompeting natives. The threat of native island assemblages generally increases with isolation and the number of endemics featured, but also with human‐associated disturbance and land use. Based on this, the Canary Island native plant systems should be highly threatened by invasives, similar to other oceanic islands globally. However, Canarian native plant systems are only weakly infiltrated and are rarely directly threatened by invasive plants. Further, highly disturbed areas, usually among the first colonized by invasives on islands, are recolonized here by natives. Based on this, we postulate four hypotheses (climatic filter, well‐preservation status, human legacy and permanent colonization) for explaining this unusual behaviour of plant systems on the Canary Islands, providing an opportunity to understand the drivers and processes behind invasion into plant communities on islands.