bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multiple molecular characteristics of circulating enterovirus types among paediatric hand, foot and mouth disease patients after EV71 vaccination campaign in Wuxi, China
Authors: Kang Yan-Jun , Shi Chao , Zhou Jian , Qian Jun , Qiu Yuanwang , Ge Guizhi 
Published: April 2022

Abstract
The molecular properties of the circulating causative agents of hand, foot and mouth disease (HFMD) in Wuxi remain unclear, posing diagnostic and prevention challenges. Additionally, in several regions of mainland China, the EV71 immunisation drastically reduced related cases and altered the HFMD pathogen spectrum, while the precise situation in Wuxi remained unknown. To address these issues, paediatric HFMD cases diagnosed in the clinic were enrolled and anal swabs were acquired in the spring of 2019. The 5′-UTR and VP1 genes were interpreted using RT-nPCR with degenerate primers to confirm their genotypes. Following that, the entire genome sequences of each viral type were recovered, allowing for the interpretation of several molecular properties. A total of 249 clinically confirmed HFMD cases had their anal swabs taken for viral identification, from which the genome sequences of seven genotypes were recovered. Coxsackievirus A16 is the most prevalent type, followed by Coxsackievirus A6, A10, A2, A4, A5 and Echovirus 11, all of which were genetically determined for the first time in Wuxi. Phylogenetic and recombination analyses were used to evaluate their evolutionary relationships with other strains found in other regions. Noticeably, a CVA16 subtype, responsible for a large proportion of the observed cases, phylogenetically clustered within clade B1a along with some strains from other countries, was the first one to be reported in China. Furthermore, some recombination events were inferred from strains detected in sporadic cases, particularly the recombination between CVA2 and CVA5 strains. Our investigation elucidated the multiple molecular characteristics of the HFMD causal enterovirus strains in Wuxi, underlining the potential hazards associated with these circulating viral types in the population and aiding in future surveillance and prevention of this disease.
Adolescents’ internalizing symptoms predict dating violence victimization and perpetration 2 years later
Authors: Psychogiou Lamprini , Ahun Marilyn N. , Geoffroy Marie-Claude , Brendgen Mara , Côté Sylvana M. 
Published: April 2022

AbstractThe aim of this longitudinal study was to examine bidirectional associations of adolescents’ internalizing symptoms with dating violence victimization and perpetration. We conducted secondary analyses of the Québec Longitudinal Study of Child Development data (n = 974). Each adolescent completed items from the Conflict Tactics Scale (at ages 15 and 17 years) to assess psychological, physical, and sexual dating violence victimization and perpetration in the past 12 months. Adolescents’ symptoms of depression and general anxiety in the past 12 months were self-reported (at ages 15 and 17 years) using The Mental Health and Social Inadaptation Assessment for Adolescents. There were concurrent associations of adolescents’ internalizing symptoms with dating violence victimization and perpetration. Internalizing symptoms at age 15 years were positively associated with dating violence victimization and perpetration 2 years later in both males and females, even after adjusting for baseline characteristics. However, neither dating violence victimization nor perpetration at age 15 years was associated with internalizing symptoms 2 years later. For males and females, internalizing symptoms put adolescents at risk for future dating violence victimization and perpetration. Interventions that target internalizing symptoms may have the potential to decrease subsequent dating violence.
Successful occlusion of a feeding artery with Amplatzer Piccolo Occluder in a patient diagnosed with Scimitar syndrome
Authors: Gursu Hazım Alper , Ozelce Bilal , Cetin Ibrahim İlker 
Published: April 2022

AbstractScimitar syndrome is a congenital anomaly in which some or all of right pulmonary veins drain into inferior caval vein. It is associated with anomalous systemic arteries arising from descending aorta supplying to right lung. Transcatheter embolisation of this artery prevents complications. We present a 2.5-year-old girl in which anomalous artery was embolised using Amplatzer PiccoloTM Occluder, for first time.
Survey of weed flora and weed management practices in Florida strawberry fields
Authors: Boyd Nathan S. , Reuss Laura 
Published: April 2022

AbstractA survey of weed flora and basic weed management practices was conducted in commercial strawberry [Fragaria × ananassa (Weston) Duchesne ex Rozier ssp. ananassa] fields in central Florida during the 2019 to 2020 field season. Forty-one fields on 14 farms were surveyed, which represents a total of 907 ha or 23% of the acreage planted to strawberries in Florida. All conventional fields were fumigated, and combinations of chloropicrin and 1,3-dichloropropene were used on 72% of the fumigated acreage. Preemergence or postemergence herbicides were used in row middles on 100% of the conventional acreage, but preemergence herbicides applied under the plastic mulch were only used on 12% of the acreage. A total of 47 weed species were identified during the survey. The five weed species with the highest frequency were goosegrass [Eleusine indica (L.) Gaertn.], cutleaf evening primrose (Oenothera laciniata Hill), Carolina geranium (Geranium carolinianum L.), common ragweed (Ambrosia artemisiifolia L.), and eclipta [Eclipta prostrata (L.) L.] which occurred in 83%, 63%, 58%, 58%, and 46% of all fields surveyed, respectively. The five species with the highest overall relative abundance were E. indica, O. lanciniata, G. carolinium, A. artemisiifolia, and Brazil pusley (Richardia brasiliensis Gomes). The frequency and distribution of E. indica is of particular concern, because populations in strawberry fields are thought to be resistant to paraquat, which is the primary herbicide used for crop termination. Weed density tended to be low overall, which suggests the integrated weed management (IWM) programs adopted by most growers are effective. Mean weed density tended to be similar on conventional and organic fields and unaffected by fumigant applied the year of the survey or the number of years strawberries had been grown consecutively in a field. Weed management research moving forward should focus on the development of IWM programs for E. indica, O. lanciniata, G. carolinium, and A. artemisiifolia.
Callisto's Atmosphere and Its Space Environment: Prospects for the Particle Environment Package on Board JUICE
Authors: Galli A. , Vorburger A. , Carberry Mogan S. R. , Roussos E. , Stenberg Wieser G. , Wurz P. , Föhn M. , Krupp N. , Fränz M. , Barabash S. , Futaana Y. , Brandt P. C. , Kollmann P. , Haggerty D. K. , Jones G. H. , Johnson R. E. , Tucker O. J. , Simon S. , Tippens T. , Liuzzo L. 
Published: April 2022

AbstractThe JUpiter ICy moons Explorer (JUICE) of the European Space Agency will investigate Jupiter and its icy moons Europa, Ganymede, and Callisto, with the aim to better understand the origin and evolution of our Solar System and the emergence of habitable worlds around gas giants. The Particle Environment Package (PEP) on board JUICE is designed to measure neutrals and ions and electrons at thermal, suprathermal, and radiation belt energies (eV to MeV). In the vicinity of Callisto, PEP will characterize the plasma environment, the outer parts of Callisto's atmosphere and ionosphere and their interaction with Jupiter's dynamic magnetosphere. Roughly 20 Callisto flybys with closest approaches between 200 and 5,000 km altitude are planned over the course of the JUICE mission. In this article, we review the state of the art regarding Callisto's ambient environment and magnetospheric interaction with recent modeling efforts for Callisto's atmosphere and ionosphere. Based on this review, we identify science opportunities for the PEP observations to optimize scientific insight gained from the foreseen JUICE flybys. These considerations will inform both science operation planning of PEP and JUICE and they will guide future model development for Callisto's atmosphere, ionosphere, and their interaction with the plasma environment.
The Influence of Crustal Magnetic Fields on the Martian Bow Shock Location: A Statistical Analysis of MAVEN and Mars Express Observations
Authors: Garnier P. , Jacquey C. , Gendre X. , Génot V. , Mazelle C. , Fang X. , Gruesbeck J. R. , Sánchez‐Cano B. , Halekas J. S. 
Published: April 2022

AbstractPrevious missions underlined the complex influence of the crustal magnetic fields on the Martian environment, including the plasma boundaries. Their influence on the bow shock is however poorly constrained, with most studies showing North/South differences attributed to the crustal fields, with various conclusions from little to strong variabilities. We analyze for the first time in detail the influence of crustal fields on the Martian shock location based on a multi‐mission analysis (MAVEN and MEX). We introduce the angular distance to the strongest crustal field region in the southern hemisphere that induces the largest influence (but not unique, with a minimum pressure threshold analyzed). Its impact is at large scale (>40–60° around), is modulated by the local time of the strongest source region (with no influence beyond terminator), and maximizes when the Interplanetary Magnetic field (IMF) is stable during the preceding hours. We introduce a technique, that is, partial correlations, to provide a coherent picture for both MAVEN/MEX due to existing cross correlations with Extreme UltraViolet (EUV). A composite parameter is proposed, that represents the combined influence of EUV, magnetosonic mach number (two major drivers) and crustal fields, the latter having an impact of hundreds of km. The influence of crustal fields on the shock appears seasonal and correlated with the Total Electronic Content, revealing a large scale coupling between the crustal fields, the ionosphere and the shock. The crustal field influence on the shock is thus significant and complex, with a coupling to both the ionosphere below and the IMF above.
Subglacial Discharge Reflux and Buoyancy Forcing Drive Seasonality in a Silled Glacial Fjord
Authors: Hager Alexander O. , Sutherland David A. , Amundson Jason M. , Jackson Rebecca H. , Kienholz Christian , Motyka Roman J. , Nash Jonathan D. 
Published: April 2022

AbstractFjords are conduits for heat and mass exchange between tidewater glaciers and the coastal ocean, and thus regulate near‐glacier water properties and submarine melting of glaciers. Entrainment into subglacial discharge plumes is a primary driver of seasonal glacial fjord circulation; however, outflowing plumes may continue to influence circulation after reaching neutral buoyancy through the sill‐driven mixing and recycling, or reflux, of glacial freshwater. Despite its importance in non‐glacial fjords, no framework exists for how freshwater reflux may affect circulation in glacial fjords, where strong buoyancy forcing is also present. Here, we pair a suite of hydrographic observations measured throughout 2016–2017 in LeConte Bay, Alaska, with a three‐dimensional numerical model of the fjord to quantify sill‐driven reflux of glacial freshwater, and determine its influence on glacial fjord circulation. When paired with subglacial discharge plume‐driven buoyancy forcing, sill‐generated mixing drives distinct seasonal circulation regimes that differ greatly in their ability to transport heat to the glacier terminus. During the summer, 53%–72% of the surface outflow is refluxed at the fjord's shallow entrance sill and is subsequently re‐entrained into the subglacial discharge plume at the fjord head. As a result, near‐terminus water properties are heavily influenced by mixing at the entrance sill, and circulation is altered to draw warm, modified external surface water to the glacier grounding line at 200 m depth. This circulatory cell does not exist in the winter when freshwater reflux is minimal. Similar seasonal behavior may exist at other glacial fjords throughout Southeast Alaska, Patagonia, Greenland, and elsewhere.
Impact of Space Environment on Geostationary Meteorological Satellite Data Outage
Authors: Sakaguchi Kaori , Nagatsuma Tsutomu 
Published: April 2022

AbstractImpact of space environment changes on geostationary meteorological satellite services, such as data outage, incomplete imagery, or quality degradation were investigated using event logs of Himawari‐8 and Meteosat (MET‐7 and MET‐8) in 2015–2017. The event logs show that such failures were caused by anomalies on spacecraft and in ground system half each. On Himawari‐8, a total of 11 incomplete imagery occurred due to spacecraft anomaly, and among them about 45% (5 anomalies) occurred during energetic electron enhancement and about 9% (1 anomaly) occurred during energetic proton enhancement. In cases of Meteosat, a total of 84 service alerts occurred due to spacecraft anomaly, and among them 35% (29 anomalies) occurred during electron enhancement and 7% (6 anomalies) occurred during both proton and electron enhancement. On the basis of statistical analysis, it is found that the probability of spacecraft anomaly occurrence markedly increases when electron fluence exceeds a threshold. The probability of anomaly is less than 10% when the 1‐MeV electron fluence is less than 104 (/cm2 sr eV), whereas it increases to more than 20% above the fluence. Thresholds are also found for electron fluences at other energies from 200 keV to 1.5 MeV. This study clarifies that changes in the space environment, particularly electron fluence enhancement affect geostationary meteorological satellite services.
Quantifying the Sheath Impedance of the Electric Double Probe Instrument on the Van Allen Probes
Authors: Hartley D. P. , Christopher I. W. , Kletzing C. A. , Kurth W. S. , Santolik O. , Kolmasova I. , Wygant J. R. , Bonnell J. W. 
Published: April 2022

AbstractSpherical double probe electric field sensors become electrically coupled to magnetospheric plasma during operation, leading to an instrument response that varies with the local plasma environment. Here, a method is developed for determining this variable coupling impedance for each measurement direction by using periods of favorable boom, wave, and magnetic field geometry. Comparing electric field complex amplitudes between 30 Hz and 10 kHz observed along each boom direction to those predicted from simultaneous magnetic field measurements and cold plasma theory allows for the amplitude and phase response of the instrument to be quantified over the full range of plasma densities encountered on‐orbit. A sheath model is developed to describe how the sheath resistance, sheath capacitance, and relative effective length vary as a function of plasma density. An additional empirical correction is also included to describe the phase response along the spin‐axis. The modeled sheath correction is subsequently tested for case studies of burst‐mode data and statistical analyses of survey‐mode data. It is demonstrated that the levels of agreement between observations and theoretical predictions based on Faraday's Law are substantially greater for the sheath corrected data than for uncorrected observations. Comparisons between observations with oppositely directed Poynting vector directions reveals that the sheath correction reconciles a bifurcated distribution in the uncorrected data to a single peak centered on agreement with Faraday's Law. A full sheath corrected EMFISIS L4 survey mode data set has been produced for final archive. Full details of the sheath correction are also provided for manual data correction.
Broadly neutralizing antibodies against Omicron-included SARS-CoV-2 variants induced by vaccination
Authors: Chi Xiangyang , Guo Yingying , Zhang Guanying , Sun Hancong , Zhang Jun , Li Min , Chen Zhengshan , Han Jin , Zhang Yuanyuan , Zhang Xinghai , Fan Pengfei , Zhang Zhe , Wang Busen , Zai Xiaodong , Han Xuelian , Hao Meng , Fang Ting , Xu Jinghan , Wu Shipo , Chen Yi , Fang Yingying , Dong Yunzhu , Sun Bingjie , Zhang Jinlong , Li Jianmin , Zhao Guangyu , Yu Changming , Zhou Qiang , Chen Wei 
Published: April 2022

AbstractThe SARS-CoV-2 Omicron variant shows substantial resistance to neutralization by infection- and vaccination-induced antibodies, highlighting the demands for research on the continuing discovery of broadly neutralizing antibodies (bnAbs). Here, we developed a panel of bnAbs against Omicron and other variants of concern (VOCs) elicited by vaccination of adenovirus-vectored COVID-19 vaccine (Ad5-nCoV). We also investigated the human longitudinal antibody responses following vaccination and demonstrated how the bnAbs evolved over time. A monoclonal antibody (mAb), named ZWD12, exhibited potent and broad neutralization against SARS-CoV-2 variants Alpha, Beta, Gamma, Kappa, Delta, and Omicron by blocking the spike protein binding to the angiotensin-converting enzyme 2 (ACE2) and provided complete protection in the challenged prophylactic and therapeutic K18-hACE2 transgenic mouse model. We defined the ZWD12 epitope by determining its structure in complex with the spike (S) protein via cryo-electron microscopy. This study affords the potential to develop broadly therapeutic mAb drugs and suggests that the RBD epitope bound by ZWD12 is a rational target for the design of a broad spectrum of vaccines.
Emergence of local scaling relations in adsorption energies on high-entropy alloys
Authors: Saidi Wissam A. 
Published: April 2022

AbstractAlloying has been proposed to circumvent scaling relations between the adsorption energies thus allowing for the complete optimization of multistep reactions. Herein the fidelity of scaling rules on high-entropy alloy (HEA) surfaces is assessed focusing on hydrogen-containing molecules, *AHx for A = C and N (x = 0, 1, 2, 3), A = S (x = 0, 1, 2) and A = O (x = 0, 1). Using an adsorbate- and site-specific deep learning model to rapidly compute the adsorption energies on CoMoFeNiCu HEA surfaces, the energies of *AHx and *A are shown to be linearly correlated if *A and *AHx have identical adsorption site symmetry. However, a local linear dependence emerges between the configuration-averaged adsorption energies irrespective of the site symmetry. Although these correlations represent a weaker form of the scaling relationships, they are sufficient to prohibit the optimization of multistep reactions. The underpinning of this behavior is twofold (1) the nearsightedness principle and (2) the narrow distribution of the adsorption energies around the mean-field value. While the nearsightedness is general for all electronic systems, the second criterion applies in HEAs with relatively strong reactive elements. The present findings strongly suggest that alloys may not generally enable the breaking of scaling relationships.
Dilute carbon in H3S under pressure
Authors: Wang Xiaoyu , Bi Tiange , Hilleke Katerina P. , Lamichhane Anmol , Hemley Russell J. , Zurek Eva 
Published: April 2022

AbstractRecently, room temperature superconductivity was measured in a carbonaceous sulfur hydride material whose identity remains unknown. Herein, first-principles calculations are performed to provide a chemical basis for structural candidates derived by doping H3S with low levels of carbon. Pressure stabilizes unusual bonding configurations about the carbon atoms, which can be six-fold coordinated as CH6 entities within the cubic H3S framework, or four-fold coordinated as methane intercalated into the H-S lattice, with or without an additional hydrogen in the framework. The doping breaks degenerate bands, lowering the density of states at the Fermi level (NF), and localizing electrons in C-H bonds. Low levels of CH4 doping do not increase NF to values as high as those calculated for $$Im\bar{3}m$$

I
m

3

¯

m

-H3S, but they can yield a larger logarithmic average phonon frequency, and an electron–phonon coupling parameter comparable to that of R3m-H3S. The implications of carbon doping on the superconducting properties are discussed.
White matter microstructure of superior longitudinal fasciculus II is associated with intelligence and treatment response of negative symptoms in patients with schizophrenia
Authors: Lee Joonho , Oh Jong-Soo , Park Chun-Il , Bang Minji , Sung Gihye , Jung Sra , Lee Sang-Hyuk 
Published: April 2022

AbstractAlthough the potential role of superior longitudinal fasciculus (SLF) in intellectual deficits and treatment response (TR) in patients with schizophrenia (SZ) has been previously described, little is known about the white-matter (WM) integrity of SLF subcomponents (SLF I, II, III, and arcuate fasciculus) and their particular relationships with the clinical presentations of the illness. This study examined the associations between fractional anisotropy (FA) of SLF subcomponents and intelligence level and 6-month treatment response (TR) of negative symptoms (NS) in patients with SZ. At baseline, 101 patients with SZ and 101 healthy controls (HCs) underwent structural magnetic resonance imaging. Voxel-wise group comparison analysis showed significant SLF FA reductions in patients with SZ compared with HCs. Voxel-wise correlation analyses revealed significant positive correlations of FAs of right SLF II with Korean–Wechsler Adult Intelligence Scale at baseline and the percentage reduction of negative syndrome subscale of the Positive and Negative Syndrome Scales at 6 months. These findings suggest that aberrance in WM microstructure in SLF II may be associated with intellectual deficits in patients with SZ and TR of NS, which may support the potential role of SLF II as a novel neuroimaging biomarker for clinical outcomes of the illness.