bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aktivitas Antioksidan Secara Kualitatif Pada Infused Water Kulit Buah Naga Super Merah (Hylocereus costaricensis (F.A.C. Weber) Britton & Rose)
Authors: Nisvia Azahra Aulya  , Kiki Mulkiya Yuliawati  
Published: March 2022

Abstract. Dragon fruit skin which is considered as waste actually contains a variety of beneficial compounds. In this study, an effort has been made to utilize dragon fruit peel waste in the form of infused water products. This study aims to determine how the effect of contact time and water temperature on antioxidant activity qualitatively in infused water of “Super Red” dragon fruit skin (Hylocereus costaricensis (F.A.C. Weber) Britton & Rose). The research method was carried out through several stages, namely material preparation, dragon fruit peel extraction and qualitative analysis of antioxidant activity. In the preparation of materials, dragon fruit preparation was carried out, material determination, simplisa preparation, simplicia characterization and phytochemical screening. Simplicia characterization includes bitterness index, expansion index, foaming index and fish index. Furthermore, in the manufacture of “Super Red” dragon fruit skin infused water, extraction was carried out using water solvent in a ratio of 1: 10. Qualitative analysis of antioxidant activity was carried out using the color reagent method. The results showed that there was an effect of contact time and water temperature on antioxidant activity in super red dragon fruit skin infused water. The highest antioxidant activity was produced by infused water which was processed at low temperature with a contact time of 6 hours (S1W2).
Abstrak. Kulit buah naga yang dianggap sebagai limbah sebenarnya mengandung beragam senyawa bermanfaat. Dalam penelitian ini, telah dilakukan salah satu upaya pemanfaatan limbah kulit buah naga dalam bentuk produk infused water. Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh lama waktu kontak dan suhu air terhadap aktivitas antioksidan secara kualitatif pada infused water kulit buah naga “Super Merah” (Hylocereus costaricensis (F.A.C. Weber) Britton & Rose). Metode penelitian yang dilakukan melalui beberapa tahap yaitu penyiapan bahan, ekstraksi kulit buah naga dan analisis kualitatif aktivitas antioksidan. Pada penyiapan bahan dilakukan penyiapan buah naga, determinasi bahan, pembuatan simplisa, karakterisasi simplisia dan penapisan fitokimia. Karakterisasi simplisia meliputi indeks kepahitan, indeks pengembangan, indeks pembusaan dan indeks ikan. Selanjutnya, pada pembuatan infused water kulit buah naga “Super Merah” dilakukan ekstraksi menggunakan pelarut air dengan perbandingan 1 : 10. Analisis kualitatif aktivitas antioksidan dilakukan menggunakan metode pereaksi warna. Hasil penelitian menunjukan bahwa terdapat pengaruh lama waktu kontak dan suhu air terhadap aktivitas antioksidan pada infused water kulit buah naga super merah. Aktivitas antioksidan tertinggi dihasilkan infused water yang di proses pada suhu rendah dengan lama waktu kontak 6 jam (S1W2).
Pengaruh Model Pembelajaran E-Learning terhadap Motivasi Belajar Mahasiswa UNISBA
Authors: Ayu Irra Kusyafira  , Dewi Rosiana  
Published: March 2022

Abstract. E-learning is a learning media on internet that can connect lecturers and students in an online learning class to overcome the time and space limitation. E-learning models that can be implemented are the Synchronous and Asynchronous. This research is aimed to discover how Synchronous, Asynchronous, and the simultaneous E-Learning models influence learning motivation among UNISBA’s students. Under quantitative approach, this research is designed as causal non experimental research using questionnaires as data collecting technique which then analyzed under regression testing tool on SPSS. The data are compiled from 376 UNISBA’s students as respondents. The questionnaire on E-Learning model as measuring tool is built by adopting Zlatko Nedelko’s strength and weakness concept on E-learning, while the learning motivation measuring tool is built by Amanillah S., and Rosianda D. Researcher found out that the Synchronous learning model has significant positive impact of 36,8% on students’ learning motivation, while Asynchronous model has 3,5% significant positive result. If implemented simultaneously, E-Learning model has a significant positive result of 40,5% on students’ learning motivation.
Abstrak. E-learning merupakan media pembelajaran internet yang dapat menghubungkan dosen dan mahasiswa di ruang pembelajaran online untuk mengatasi kendala ruang dan waktu. Model pembelajaran E-learning yang diterapkan yaitu Synchronous dan Asynchronous. Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh pembelajaran Synchronous terhadap motivasi belajar mahasiswa UNISBA, mengetahui bagaimana pengaruh pembelajaran Asynchronous terhadap motivasi belajar mahasiswa UNISBA, serta pengaruh model pembelajaran E-Learning terhadap motivasi belajar mahasiswa UNISBA. Penelitian ini menggunakan pendekatan kuantitatif dengan desain penelitian kausal non-eksperimental dan teknik pengumpulan data menggunakan kuesioner. Teknik analisis menggunakan pengujian regresi dengan SPSS. Penelitian ini melibatkan 376 mahasiswa UNISBA. Alat ukur yang digunakan dalam penelitian ini adalah kuesioner model pembelajaran E-Learning yang dibuat dengan menurunkan konsep kelebihan dan kekurangan dari Nedelko. Alat ukur motivasi belajar yang dibuat oleh Amanillah, S., & Rosiana, D. Hasil penelitian menunjukkan bahwa model membelajaran Synchronous memiliki pengaruh positif signifikan tehadap motivasi belajar pada mahasiswa UNISBA sebesar 36,8%, model pembelajaran Asynchronous memiliki pengaruh positif signifikan tehadap Motivasi Belajar pada mahasiswa UNISBA sebesar 3,5%, serta secara simultan model pembelajaran E-Learning memiliki pengaruh positif signifikan terhadap motivasi belajar mahasiswa UNISBA sebesar 40,5%.
Designing the learning trajectory for the topic of circles through a tambourine context
Authors: Juniarti Anita , Jojo Zingiswa , Prahmana Rully Charitas Indra 
Published: March 2022

A tambourine is one of the musical instruments commonly used in Islam. It is also used in an extracurricular activity in various schools so that many students are familiar with the instrument, making it relevant for learning mathematics. Furthermore, there is an approach to learning mathematics called Indonesian Realistic Mathematics Education (IRME), where students start the learning with contexts close to their lives. This study aims to design a learning trajectory using the IRME approach with a tambourine context to support students' understanding of circles. This learning progresses from the informal stage to the formal through the IRME approach. The study applied design research with three stages: preliminary design, design experiments, and retrospective analysis. The research subjects were 19 six-grade students in one of the elementary schools in Balangan, South Kalimantan, Indonesia. The instruments used were videos to observe the learning process and how students work on the questions given, photos to reference students’ work, and a test in a student worksheet to obtain data on students’ work. The results reveal the learning trajectory practised using the tambourine as the context seen in the student's daily activities. The learning trajectory consists of four events: assembling the tambourine, drawing an illustration of the tambourine, listing the parts of a circle, and solving a problem related to the parts of the circle. In addition, this study also shows that learning trajectory activities have essential roles in supporting students' understanding of the concept of a circle.
CARACTERÍSTICAS CLÍNICAS Y EPIDEMIOLÓGICAS DE LAS MORDEDURAS DE MAMÍFEROS
Authors: SHIROMA TAMASHIRO Patricia 
Published: March 2022

Objective: To describe clinical and epidemiological characteristics of mammalian bites in Ate district, Lima-Peru. Method: Retrospective descriptive observational study. 721 care records of bitten patients were analyzed in the district of Ate (Lima-Peru), during the period 2015-2018. Causality was estimated using the odds ratio (OR) and the statistical association with the Chi-square test. Results: 53,6% of the cases were in men. The mean age was 29,6 years. Also, 95% of the attacks were caused by dogs. However, children between 0 and 11 years old (OR:1,78; IC: 1,26-2,49) had a higher risk of being bitten by known animals in the craniofacial region (OR: 2,31; IC: 1,34-3,98). Conclusion: The results allowed us to identify that the characteristics of mammalian bite injuries vary according to the aggressor species, age and gender of the victim.
Hemofilia adquirida
Authors: Milanesio Martín , Tabares Aldo Hugo , Caeiro Gastón Andrés , Olmedo Julieta , Montivero Ana Romina 
Published: March 2022

Introducción: La hemofilia adquirida es un trastorno de la hemostasia que se produce por la presencia de autoanticuerpos inhibidores dirigidos contra el factor VIII de la coagulación. Clínicamente se manifiesta por sangrados espontáneos principalmente en piel y tejidos blandos, y a diferencia de la hemofilia hereditaria, la presencia de hemartrosis es infrecuente. Si bien muchos casos son idiopáticos, se deben buscar causas secundarias ya que el tratamiento de las mismas es clave en el pronóstico de la enfermedad. Dentro de estas destacan la presencia de neoplasias, enfermedades autoinmunes, fármacos, embarazo y postparto. El tratamiento se basa en medidas hemostáticas y terapias que permitan erradicar el autoanticuerpo.
Metodología: En el siguiente manuscrito describimos cuatro pacientes con hemofilia adquirida con diferentes etiologías, tratamientos y pronóstico.
Resultados: Los cuatro pacientes presentaron resolución del sangrado tras el tratamiento específico.
Conclusión: La hemofilia adquirida es un trastorno raro de la hemostasia que debe sospecharse en pacientes con hematomas extensos espontáneos sin coagulopatía previa. Si bien en muchos casos no se encuentra una etiología subyacente, deben buscarse causas secundarias ya que el tratamiento de las mismas es clave para la evolución del paciente.
KEMAMPUAN MEMPRODUKSI TEKS EKSPOSISI SISWA SEKOLAH MENENGAH ATAS DI KOTA MATARAM DITINJAU DARI ASPEK STRUKTUR TEKS EKSPOSISI
Authors: Rosmayanti Nur Ida , Mahsun Mahsun , Mahyudi Johan 
Published: March 2022

This study aims to describe the ability to produce Non-Literature Genre Text of High School in Mataram City,West Nusa Tenggara .The problem in this research are : How is the ability to produce exposition text by students senior high school based on the structure of the exposition text. The approach used in this study is a qualitative and quantitative approach. Population Data of this research are exposition text.The methode of data collection is done by listening to the method of proficiency involved.Data were analyzed qualitative and quantitative then presented through informal methods. The result of this study indicate that the ability of students Senior High School of Mataram city in producing exposition text is in the category of underprivileged, that is equal to 57,50 under category of sufficiently capable score (67-78). The inability appear also qualitatively in lack of proper use of understanding of based exposition text.
The Safety Profile of Single Daily Dose of Aminoglycosides in Comparison with Multiple Daily Dose
Authors: A. Baker Amanj , A. Majeed Ibrahim , K. Ismail Dawser 
Published: March 2022

To overcome the problems which associated with the standard multiple daily doses (MDD)
of aminoglycosides (AGs) like high incidence of toxicity(nephrotoxicity, ototoxicity)(5-25%) and high cost, an alternative approach was developed which was single daily dose (SDD).This new regimen was designed to maximize bacterial killing by optimizing the peak concentration/minimum inhibitory concentration(MIC)ratio and to reduce the potential for toxicity. The study includes 75 patients selected randomly, 50 of them received SDD regimen of age range of 17-79 years and the remaining received MDD regimen of age range of 13-71 years. The study was designed to evaluate the safety of SDD regimen in comparison with MDD regimen. All the patients in SDD group received a constant dose of 5-mg/kg/day of gentamicin and 20mg/kg/day of amikacin with a drug administration interval based on estimated creatinine clearance(CLcr): if â‰¥60 ml//min every 24 hours (q24h), 59- 40 ml/ min every 36hours and 39- 30 ml/min every 48 hours.The calculated dose was diluted with 0.9% normal saline or 5% dextrose to 50-100 ml and given as intravenous infusion over 30-60 minutes. In SDD group , the mean length of therapy was 6.4Â±1.73 days .Gentamicin accounted for 96% of the aminoglycoside use, and the majority(58%) of patients received the drug every 24 hours.The 36- and -48 hours intervals were used for 34 and 8% of the population, respectively.While in MDD group , the mean length of therapy was 5.0Â±0.91 days. Gentamicin accounted for all (100%) of aminoglycoside use, and all of the patients received the drug every 8 hours. No clinically apparent ototoxicity and nephrotoxicity were observed in the patients in the SDD group, in contrast to the patients in MDD group, in whom 4 patients (16%) were developed nephrotoxicity and 1 patient (4%) was developed ototoxicity. The obtained results indicate that SDD regimen was safer through decreasing the incidence of both nephrotoxicity and ototoxicity.For statistical analysis, ANOVA test was used with P<0.01.Each mean was expressed as meanÂ±SEM(Standard Error of Mean).
Key words: Aminoglycosides, Single Daily Dose, Nephrotoxicity and Ototoxicity.
Isolation of Some Microorganisms from Bar Soaps and Liquid Soaps in Hospital Environments
Authors: M.H. Zeiny Sarmad 
Published: March 2022

This study was designed to determine the colonization of the in-use hand washing soaps in hospital settings. It is a comparative cross-sectional research in a surgical specialties and Baghdad teaching hospital in Baghdad, Iraq. Swabs from surfaces of bar soaps and from liquid soaps via their applicator tips; at the sinks of toilets of hospital staff and working rooms of the wards were taken in January 2008. Conventional microbiologic methods were used for culture of the swabs and identification of the isolates. Colonization was detected 60% and 15.9% in bars and liquid forms respectively. And this lead to the conclusion that bar soaps could be colonized with microorganisms excessively. Liquid hand washing soaps are more appropriate in hospital environments. Proper using conditions of the hand washing items should be defined in health care settings.
Keywords: Bar soap, liquid soap, pseudomonas aeruginosa, nosocomial infections.
Dose-dependent Anti-inflammatory Effect of Silymarin in Experimental Animal Model of Acute Inflammation
Authors: M. Juma'a Kasim , A. Hussain Saad , T. Numan Intesar , H. Siqar Assad 
Published: March 2022

Silymarin, a flavolignans from seeds of â€˜milk thistleâ€™ â€œSilybum marianumâ€ has been widely used from ancient times because of its excellent hepatoprotective action. It has been used clinically to treat liver disorders including acute and chronic viral hepatitis, toxin/drug-induced hepatitis and cirrhosis and alcoholic liver disease. The efficacy and dose-response effect of silymarin (125, 250 and 500 mg/kg) were assessed using egg albumin-induced paw edema in rats as a model of acute inflammation. In this model, 56 rats were used and allocated into 7 subgroups each containing 8 rats. All treatments were given intraperitonealy 30 minutes before induction of inflammation by egg albumin and then the increase in paw edema was measured 1h, 2h and 3h after induction of inflammation by using the vernier caliper. The results indicated that silymarin, at doses range used, significantly lowered paw edema (P<0.05) an effect comparable to that produced by the reference drugs, acetyl salicylic acid, meloxicam and dexamethazone. Paw edema suppressive effect of silymarin 250 and 500 mg/kg was comparable and both of them were significantly different from that of silymarin 125 mg/kg (P<0.05). Therefore, silymarin exert an important anti-inflammatory activity in animal model of acute inflammation, which was significantly increased as the dose increased up to 250 mg/kg.
Key words: Silymarin, acute inflammation, dose-response
Preliminary Cytotoxic Study of Some Novel Furo-2-quinolone Compounds
Authors: A.AlOmari Nohad , O. Omar Adnan , M. Taher Iklas 
Published: March 2022

In this research, new series of Furo-2-quinolone [FQ] compounds have been synthesized. These novel [FQ] compounds were prepared from coumarin derivatives (Furocoumarins: psoralen and isopsoralen).Identifications of these FQ compounds were performed by using infrared spectrum (I.R), Ultraviolet spectrum (U.V) and Nuclear Magnetic Resonance spectrum (H1-NMR) besides some physical data. The cytotoxic screening involves ;using HEP-2 cell line which gave differential responses against tested compounds : 4,6 Dimethyl furo[2, 3-g] coumarin (C1), 1-(2`, 4`, Dimethoxy benzylideneimino)-2,6-dimethyl Furo [2, 3-g] quinoline-2-one (C3) and the angular psoralen of the same derivative with the chemical name; 1-(2`,4`-Dimethoxybenzylidenimine)-4,8,9-trimethyl furo[3,2-h] quinoline-2-one (C3A).These preliminary studies using different cell lines in addition to full cytotoxic screening may facilitate generation of better structural activity relationship and then shed the light for new lead promising anticancer compounds.
Keyword: Coumarin, Angelicin, HEP-2 Cell line, cytotoxicity,
Preventive Effects of Different Doses of Pentoxyfilline Against CCl4-Induced Liver Toxicity in Rats
Authors: I. Abd Al-Zahra Jameel , K. Ismael Dawser , N. Al-Shawi Nada 
Published: March 2022

The liver protective effects of pentoxifylline were studied through pre-treatment of rats with various intraperitoneal (IP) doses (25, 50 and 100mg/kg/day) 14 days before induction of liver toxicity by carbon tetrachloride (CCl4). The parameters of oxidative stress, malondialdehyde (MDA) and reduced glutathione (GSH) were measured in liver homogenate in addition to histopathological examinations. Analysis of data revealed significant amelioration of oxidative stress in groups of animals pre-treated with different doses of pentoxifylline (PTX) compared to group of animals intoxicated by CCl4 as evidenced by lowering MDA contents and elevation of GSH levels in liver tissue homogenate but the levels still significantly different compared to controls. Additionally, increasing doses of PTX produce a dose-dependent improvement in liver tissue damage induced by CCl4, as evident histologically by the stained liver sections. In conclusion, these findings suggest that, the hepatoprotective effects of pentoxifylline are dose dependent.
Key words: pentoxifylline, CCl4Â­, liver toxicity.
Quantitative and Qualitative Analysis of Plumbagin in the Leaf and Root of Plumbago europaea Growing Naturally in Kurdistan by HPLC
Authors: M. Muhammad Hazhar , Y. Saour Kawkab , M. Naqishbandi Alaadin 
Published: March 2022

Plumbago (Plumbaginaceae) is a genus of 10-20 species of flowering plants used in traditional Indian medicine, native to warm temperature to tropical regions of the world. The roots of Plumbago europaea, the Iraqi species of Plumbago, have been used for the treatment of cancer, rheumatoid arthritis, and dysmenorrhea. The main active constituents from dried powdered leaves and roots of Plumbago europaea were extracted by Soxhlet apparatus using ethyl acetate, the main active constituent was characterized by spectroscopic analysis (IR, 1H NMR, and 13C NMR) as plumbagin. Quantitative and qualitative study of plumbagin in the roots and leaves extracts was carried out by HPLC technique using analytical column (Eurospher 100, C18, 5 Âµm, 250 x 4.6 mm) with 10% solvent (B) isocratic elution of methanol (solvent A) and water (solvent B) at flow rate 0.75 ml/min and detection wave length of 270 nm. The percentage of plumbagin in the root and leaf extracts was recorded to be (1.9 %) and (1.5 %) respectively.
Keywords: Plumbago europaea, plumbagin, HPLC
The downhole jet pumps experimental studies efficiency improving
Authors: Kryzhanivskyy Ye. І. , Panevnyk D. O. 
Published: March 2022

On the basis of the analysis of the existing criteria of hydraulic similarity, the rules of transferring the results of laboratory tests of jet pumps to the conditions of their operation in the well are considered. The geometric similarity of the flow part of the jet pump is determined by the diameters of the working nozzle, the mixing chamber and the diffuser, the lengths of the mixing chamber and the diffuser, and the distance between the working nozzle and the mixing chamber. The kinematic similarity of mixed flows is determined by the ratio of the speeds or costs of the injected and the workflows, and the dynamic one by the relative pressure in the form of the pressure ratio of the mixed, injected and workflows. To characterize the similarity of motion modes and physical properties of flows in the flowing portion of a jet pump, a Reynolds number for working, injected, and mixed flows can be used. The functional relationship between the quantities that characterize the process of mixing threads can be represented as a relationship between the similarity criteria that are made of them. The equality of any two relevant similarity criteria made up of the basic parameters and initial boundary conditions is a sufficient sign of the similarity of the two systems. A generalized Eulerian criterion is proposed for modeling a wellbore jet pump workflow that provides a relationship between geometric, kinematic, and dynamic dimensionless complexes. Due to the structural features of the ejection systems, the generalized criterion is presented in the form of a ratio of Euler criteria of mixed and working flows, the numerical values of which do not differ from the magnitude of the relative pressure of the jet pump. As a result of the conducted researches, the values ​​of dimensionless complexes are determined, which determine the conditions for transferring the results of experimental studies of the jet pump model to the real design of the well ejection system.