bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of frontostriatal circuits in adolescent nicotine addiction and internet gaming disorder
Authors: von Deneen Karen M. , Hussain Hadi , Waheed Junaid , Xinwen Wen , Yu Dahua , Yuan Kai 
Published: January 2022

Abstract

Background
Recently, there has been significantly increased participation in online gaming and other addictive behaviors particularly in adolescents. Tendencies to avoid social interaction and become more involved in technology-based activities pose the danger of creating unhealthy addictions. Thus, the presence of relatively immature cognitive control and high risk-taking properties makes adolescence a period of major changes leading to an increased rate of emotional disorders and addiction.

Aims
The critical roles of frontostriatal circuits in addiction have become the primary focus associated with reward in the striatum and cognitive control in the PFC. Internet gaming disorder (IGD) and nicotine addiction are currently becoming more and more serious.

Methods
In the light of neuroimaging, the similarity between brain mechanisms causing substance use disorder (SUD) and IGD have been described in previous literature.

Results
In particular, two distinct brain systems affect the way we act accounting for uncharacteristic neural function in addiction: the affective system comprises of the striatum driven by emotional, reward-related, and internal stimuli, and a cognitive system consisting of the prefrontal cortex (PFC) supporting the ventral affective system's actions via inhibitory control.

Discussion and Conclusion
Therefore, as a novel concept, we focused on the implication of frontostriatal circuits in nicotine addiction and IGD by reviewing the main findings from our studies compared to those of others. We hope that all of these neuroimaging findings can lead to effective intervention and treatment for addiction especially during this critical period.
Functional connectivity between the parahippocampal gyrus and the middle temporal gyrus moderates the relationship between problematic mobile phone use and depressive symptoms: Evidence from a longitudinal study
Authors: Zou Liwei , Wu Xiaoyan , Tao Shuman , Yang Yajuan , Zhang Qingjun , Hong Xuedong , Xie Yang , Li Tingting , Zheng Suisheng , Tao Fangbiao 
Published: January 2022

Abstract

Background and aim
Problematic mobile phone use (PMPU) is prevalent and increases the risk for a variety of health problems. However, few studies have explored the neural mechanisms that might render adolescents more or less vulnerable. Here, we aimed to identify whether PMPU is associated with depressive symptoms and whether this relationship is moderated by intrinsic functional connectivity (iFC) which is associated with PMPU.

Methods
In this longitudinal study, we included 238 students (mean age = 19.05, SD = 0.81) that came from a university in Hefei, China. They all finished MRI scans at baseline and completed questionnaires both at baseline and 1 year later. A self-rating questionnaire for adolescent problematic mobile phone use and depression anxiety stress scale-21 were used to assess PMPU and depressive symptoms. We first assessed the relationship between PMPU and depressive symptoms using an autoregressive cross-lagged model. Then, we detected the brain regions that were associated with PMPU. Moreover, the neuroimaging results were extracted to explore whether the iFC of these brain regions moderated the relationship between PMPU and depression.

Results
Consistent with our hypotheses, PMPU was positively associated with depressive symptoms, and the relationship between PMPU and depressive symptoms was moderated by iFC of the left parahippocampal gyrus-right middle temporal gyrus both at baseline and after 1 year (β = 0.554, P = 0.003; β = 0.463, P = 0.016, respectively).

Conclusions
These results advance the understanding of PMPU and suggest that iFC of the left parahippocampal gyrus-right middle temporal gyrus may be a neurobiological contributor to its relationship with depressive symptoms.
Early and late postoperative complications of robot-assisted radical subcutaneous mastectomy with endoprosthesis
Authors: Kvetenadze G. E. , Shivilov E. V. , Arslanov Kh. S. , Zhukova L.  G. , Khatkov I.  E. 
Published: January 2022

Over the past two decades, the surgical treatment of breast cancer (BC) has changed from standard radical mastectomies to organ-preserving and reconstructive plastic surgeries using endovideosurgical and robotic technologies. Robot-assisted radical subcutaneous mastectomy, as a minimally invasive method of surgical treatment of BC in the early stages, is recognized as safe and effective.The results of robot-assisted radical subcutaneous mastectomy and radical subcutaneous mastectomy with endoprosthesis in 27 patients with histologically verified BC are presented. A comparative assessment of postoperative complications of robot-assisted radical subcutaneous mastectomy with endoprosthesis and radical subcutaneous mastectomy with endoprosthesis was performed. It was found that the postoperative period in robotic interventions is more favorable, which confirms the low need for analgesics, the absence of signs of the formation of hematomas of the surgical wound, as well as a decrease in the frequency of inflammatory infiltrates and gray soft tissues in the area of the postoperative suture. Performing a robot-assisted radical subcutaneous mastectomy with endoprosthesis can significantly improve the surgical and aesthetic results of BC treatment in the early stages of this disease.
Direct Estimation of Explosion Pn Green’s Functions Applied to Teleseismic P-wave Intercorrelations for North Korean Nuclear Tests
Authors: Lay Thorne 
Published: January 2022

Abstract
Seismic yields and explosion source time functions for the six declared underground nuclear tests at the North Korean test site are estimated using teleseismic waveform equalization (intercorrelation) incorporating improved source structure inferred from regional distance Pn phases. Explosion source time functions estimated by previous modeling efforts are deconvolved from the broadband Pn observations to extract direct estimates of the Pn Green’s functions. Very consistent signals are found for station MDJ (to the north) for all but the 2006 event, and a 1D layered elastic model is determined that matches the corresponding pPn signals for the larger events. The much simpler Pn Green’s functions found for INCN (to the south) are well modeled using a half-space structure. The 1D structures are incorporated into intercorrelations for teleseismic P observations. Very similar results are found using the layered MDJ model for all azimuths, or when azimuthally varying the source velocity model to have a half-space structure for stations to the south, and/or using a half-space structure for the 2006 event at all azimuths. The relative yield estimates from intercorrelation are thus stable with respect to specific 1D source structures; the full effects of 3D elastic and nonelastic structures are yet to be considered.
INTEGRATION BETWEEN UNIVERSITY AND STARTUPS IN THE LIGHT OF THE SINGULARITY AND LIMITED RATIONALITY
Authors: Lacerda Rogerio Tadeu de Oliveira , Bernardes Mayara Lucia , Ribeiro Ana Maria Simões , Simon Bianca dos Santos , Camargo Anelise Stangarlin de 
Published: January 2022

The article aims to answer the following research questions: What challenges does the academy face to improve the critical thinking of its entrepreneurial students using the action learning approach? And, what are the reactions and alternatives that students present to the singularity and limited rationality when solving a problem? To this end, a qualitative approach is used through participant observation in three case studies of companies participating in an interdisciplinary project developed at one of the best Brazilian federal university. From the cases, it is possible to perceive points such as: Prevalence of fear of failure by students; Initial research using an optimal and generic solution from the scientific literature or similar examples; Students' understanding that internal organization and learning management are more important than the technical solutions; The singularity of the startup problem, coupled with the limitation of facts and data, led the group to decide more on startup studies than generic bibliographic research on the problem or the benchmarking; and The solution validation process was carried out by the legitimacy of the entrepreneur, instead of statistical or economic validation.
Feministyczne tropy w „Obiecującej Młodej Kobiecie” Emerald Fennell
Authors: Klan Maria 
Published: January 2022

The article is an attempt to analyze the ﬁlm Promising Young Woman directed by Emerald Fennell. It contains references to feminist ﬁlm criticism and other works on this subject. It largely focuses on the visual and musical layer of production.
PENGETAHUAN GURU TENTANG KONSEP WIRAUSAHA LITERASI DALAM PEMBELAJARAN BAHASA INDONESIA DI SMA
Authors: Wulansari Keken , Zulianto Sugit , Ulya Chafit 
Published: January 2022

<p>Pembelajaran Bahasa Indonesia di sekolah merupakan pembelajaran berbasis teks produktif-apresiatif yang berpeluang bernilai wirausaha bagi siswa sehingga dibutuhkan bimbingan guru yang memiliki pengetahuan wirausaha literasi. Penelitian ini bertujuan untuk mengeksplorasi pengetahuan guru Bahasa Indonesia tentang kompetensi wirausaha. Penelitian ini merupakan penelitian deskriptif kuantitatif dengan pendekatan survei. Sumber data adalah guru Bahasa Indonesia di SMA Kota Surakarta. Teknik pengumpulan data dengan kuesioner tertutup menggunakan skala Linkert. Analisis data menggunakan statistik deskriptif dengan memperhatikan <em>mean ideal</em> dan <em>standar deviasi ideal</em>. Hasil penelitian ini menunjukkan bahwa aspek pengetahuan manajemen dan organisasi memiliki rerata persentase paling tinggi yaitu 35% dengan jumlah skor 429. Disusul oleh aspek pengetahuan bidang usaha yang ditekuni dengan rerata presentase sebesar 34% dan memiliki jumlah skor 557. Aspek yang paling rendah adalah aspek pengetahuan peran dan tanggung jawab dengan rerata presentase sebesar 31% dengan jumlah skor 337. Dengan demikian, dapat disimpulkan bahwa guru memiliki pengetahuan yang memadai mengenai manajemen dan organisasi, namun kurang mengetahui tentang peran dan tanggung jawab dalam berwirausaha sehingga perlu ditingkatkan melalui pelatihan.</p>
Perancangan Konfigurasi FTTH Jaringan Akses Fiber Optik Dengan Optisystem Dalam Modul Praktikum Komunikasi Optik
Authors: Fauzi Ahmad 
Published: January 2022

<p>Abstrak</p><p>Penelitian ini bertujuan untuk merancang modul praktikum Sistem Komunikasi Fiber Optik yang ada pada mata kuliah Jaringan Pita Lebar dan Komunikasi Optik. Penelitian ini dilakukan dengan metode perancangan dan eksperimen, yaitu dengan melaksanakan perancangan pada konfigurasi sistem jaringan fisik yang telah ada. Dengan menggunakan modul yang dirancang, pada hasilnya akan dapat dilakukan pengukuran dan perhitungan link budget rancangan tersebut. , instrumen penilaian yang digunakan dalam aktivitas pembelajaran harus dapat menilai kinerja mahasiswa berdasarkan kriteria kompetensi teknis dan supervisi yang diharapkan [1]. Perancangan jaringan Fiber To The Home (FTTH) yang dilakukan dibuat dalam perangkat lunak simulasi jaringan fiber optik, yaitu Optisystem. Sebagaimana kegiatan fisiknya, pengukuran dirancang menggunakan <em>optical power meter, Optical Time Domain Reflectometer</em> (OTDR) dan <em>BER analyzer</em> [2]. Hasil penelitiannya, dapat disusun sebuah konfigurasi FTTH yang dimuat pada modul praktikum Sistem Komunikasi Fiber Optik yang tepat berikut buku panduan praktikumnya (jobsheet) dengan nilai daya pada jaringan sebesar – 16,420 dBm, yakni memenuhi standar yang diperbolehkan.</p><p>===========</p><p>Abstract</p><p><em>This study aims to design a Fiber Optic Communication System practicum module in the Broadband Network and Optical Communication course. This research was conducted by design and experimental methods, namely by implementing the design on the existing physical network system configuration. By using the designed module, the results will be able to measure and calculate the design link budget. , the assessment instrument used in learning activities must be able to assess student performance based on the expected criteria of technical competence and supervision</em>[1]<em>. The </em>Fiber To The Home (FTTH) <em>network </em><em>design is made in optical fiber network simulation software, namely Optisystem. As with its physical activities, measurements are designed using an optical power meter, Optical Time Domain Reflectometer (OTDR) and a spectrum analyzer</em>[2]<em>. The results of the research, a FTTH configuration can be compiled which is loaded on the correct Fiber Optic Communication System practicum module along with the practical manual (jobsheet) with a power value on the network of - 16,420 dBm, which meets the allowed standards.</em></p>
Spectacular Accidental Distraction Arthroplasty in Dupuytren Contracture with Good Outcome
Authors: Degreef Ilse , Van Hoecke Emanuel , Van Nuffel Maarten 
Published: January 2022

Case:
An exceptional event occurred during gradual extension with an external fixator for recurrent small finger Dupuytren flexion deformity. A massive proximal interphalangeal joint distraction arose, possibly because of the center of rotation misalignment and a hasty patient-controlled correction. The device was removed, and a plaster splint protected the finger for 5 days to prevent dislocation of the unstable joint. It relocated with an acceptable clinical result.

Conclusion:
Gradual extension of Dupuytren contractures with an external fixator may induce severe joint distraction by eccentric placement of the device. On the other hand, the good outcome of this case report may inspire further research on controlled joint distraction in hooked deformity.
Two Single-Level Nonadjacent Corpectomies With Expandable Vertebral Body Replacements for Spinal Metastasis
Authors: Trojner Teodor , Rečnik Gregor 
Published: January 2022

Case:
The case describes a 59-year-old male patient who suffered from a solitary metastasis of unknown origin in the L1 vertebra. Owing to the instability, a corpectomy and posterior fixation with the expandable cage implantation was performed. However, the disease progressed, which required additional nonadjacent corpectomy and cranial elongation of the construct with implantation of the additional expandable cage at the level Th11.

Conclusion:
In such complex pathology, two single-level nonadjacent corpectomies and expandable cage implantations present a surgical solution that may provide a satisfactory outcome.
Anterior Compartment Neurovascular Bundle Entrapment in a Minimally Displaced Distal Tibial Fracture
Authors: Lachance Andrew D. , Shields Margaret V. , Ryan Scott P. 
Published: January 2022

Case:
A 29-year-old woman presented with a low-energy, minimally displaced pilon fracture with progressive pain and paresthesias in the affected foot, ultimately requiring open reduction and internal fixation. Intraoperatively, the deep peroneal nerve and anterior tibial artery and vein were entrapped within the fracture. After freeing the bundle and fixing the fracture, the paresthesias improved and ultimately resolved.

Conclusion:
Injury to the anterior leg compartment neurovascular structures should be considered in low-energy, minimally displaced pilon fractures. In this instance, progressive neurologic symptoms not consistent with the radiographic findings indicated the patient for surgical exploration and fixation.
Nonoperative Management of Chronically Subluxated Bilateral Cervical Facets with Bony Fusion
Authors: Humphrey Tyler , Song Junho , Zhang Andrew , Czerwein John , Chao Simon 
Published: January 2022

Case:
We describe a case of a 65-year-old woman with bilateral chronically subluxated C6 to 7 facets with facet fusion, who presented for care for the first time 1 year after a motor vehicle accident. The patient was minimally symptomatic at the time of her evaluation; thus, nonoperative treatment was provided. At 3-year follow-up, our patient remained minimally symptomatic with no progression of neurologic deficits.

Conclusion:
Consistent with previous reports, conservative management was used rather than surgical fusion in a patient with stable osseous fusion complexes and minimal neurologic symptoms.
The Malay Version of the Attitudes and Beliefs About Cardiovascular Disease (ABCD-M) Risk Questionnaire: A Translation, Reliability and Validation Study
Authors: Said Zarudin Mat , Ismail Tengku Alina Tengku , Hamid Anees Abdul , Sahathevan Ramesh , Aziz Zariah Abdul , Musa Kamarul Imran 
Published: January 2022

Abstract
BackgroundCardiovascular disease (CVD) and stroke are a global public health problems and cause high mortality, especially in low- and middle-income countries. Knowledge and awareness are critical points in managing the risk in the general population. The Attitudes and Beliefs about Cardiovascular Disease (ABCD) risk questionnaire was developed to evaluate the awareness of stroke and CVD risk. Thus, the government can set up a practical risk assessment and management programme. The initiative will encourage people to seek healthcare timely and reduce the possibilities of developing complications.ObjectiveThis study aimed to translate and validate the ABCD risk questionnaire into Malay language and evaluate the psychometric properties of the Malay version in the general population in Malaysia.MethodsThe questionnaire was translated using a standard forward–backward translation method. The validation was perfomed by both expert panels and a potential user group. Next, the exploratory factor analysis was conducted to examine factorial validity. We used Cronbach’s alpha and Raykov’s rho to explore the internal consistency and composite reliability of the 18 items from three domains. Finally, the confirmatory factor analysis (CFA) was conducted using a robust maximum likelihood estimator.ResultsThe content and face validity indices were determined to be 0.94 and 0.99 respectively. Data were obtained from 179 respondents (mean age, 36.8 years; female, 68.2%; secondary level education, 51.1%). The internal consistency and composite reliability of the domains showed good results ranging from 0.643 to 0.885. The factor loadings of each item were acceptable (>0.3), and the fit indices from the CFA resulted in a good model fit [χ2 (p-value = 0.16), SRMR = 0.054, RMSEA = 0.029, CFI = 0.99, TLI = 0.99)]. ConclusionsThe Malay version of ABCD risk questionnaire is a valid and reliable tool to assess the awareness of stroke and CVD risk in the general population in Malaysia.
Highly Differentiated Target Detection Method Based on YOLOv3 Model Under Extremely Low Light Conditions
Authors: Yan Chenxu , Shao Haijian , Deng Xing 
Published: January 2022

Abstract
Because of the dark atmosphere created by YOLO v3's poor detection accuracy, the photographs obtained in reality usually considerably improve the difficulty of target detection tasks in extremely low light settings. Under extremely low light conditions, the YOLOv3 model is used to suggest a high-discrimination target detection approach. Target detection is an essential task in the field of computer vision, in which the image is the source of input, but the image obtained in reality may make the target detection task in extremely low light conditions because of the dark environment and poor quality imaging equipment, which increases the difficulty of target detection and affects the accuracy of detection. Therefore, based on the above reasons, this paper proposes a high-discrimination target detection method based on the YOLOv3 model under extremely low light conditions. The low light enhancement algorithm based on dehazing algorithm is improved for restraining the part of the transmission rate less than 0.5 in the pixel, to enhance the contrast of the processed images. The improved low light enhancement algorithm is 5.32% higher based on the evaluation index of target detection than the original images. Coiflet wavelet transform is applied to achieve high-discrimination feature extraction of images and decompose the low-frequency features of image information at different resolutions to obtain high-frequency features in the horizontal, vertical, and diagonal directions. The eventually constructed YOLOv3 network has reduced the negative impact of the detected target on the detection accuracy under the illumination change. The results reveal that the target detection method established in this paper has been enhanced by 40.6% on low light photos when compared to the traditional YOLOv3 model, and it still has considerable advantages in comparison to other benchmark approaches in target detection models.
Infection order outweighs the role of CD4+ T cells in tertiary flavivirus infection
Authors: Marzan-Rivera Nicole , Serrano-Collazo Crisanta , Cruz Lorna , Pantoja Petraleigh , Ortiz-Rosa Alexandra , Arana Teresa , Martinez Melween , Burgos Armando , Roman Chiara , Geerling Elizabeth , Brien James , Pinto Amelia , Mendez Loyda , Sariol Carlos 
Published: January 2022

Abstract
Dengue (DENV) and Zika (ZIKV) are flaviviruses that co-circulate throughout the tropical and subtropical regions. The link between CD4+ T and B cells during immune responses to DENV and ZIKV and their roles in cross-protection during heterologous infection is an active area of research. Here we used CD4+ lymphocyte depletions to dissect the impact of cellular immunity on humoral responses during a tertiary flavivirus infection. We show that CD4+ depletion in DENV-primed animals followed by ZIKV-DENV resulted in delayed viremia followed by increased viral replication in tertiary infections and dysregulated adaptive immune responses compared to ZIKV-primed animals followed by DENV-DENV infections. We show a delay in DENV-specific IgM/IgG antibody titers and neutralization in the DENV-primed CD4-depleted animals but not in ZIKV-primed CD4-depleted animals. This study confirms the critical role of CD4+ cells in viremia control and priming of early and robust neutralizing antibody responses during sequential flavivirus infections. Our results also revealed differential cytokine profiles for both infection sequences regardless of CD4+ status. Our work here suggests that the order of flavivirus exposure affects the outcome of a tertiary infection. Our findings have implications for understanding complex immune responses induced by flaviviruses that co-circulate and develop effective flavivirus vaccines.