bluuebunny/crossref_metadata_2025_split huggingface dataset:
Blockworlds 0.1.0: a demonstration of anti-aliased geophysics for probabilistic inversions of implicit and kinematic geological models
Authors: Scalzo Richard , Lindsay Mark , Jessell Mark , Pirot Guillaume , Giraud Jeremie , Cripps Edward , Cripps Sally 
Published: May 2022

Abstract. Parametric geological models such as implicit or kinematic models provide
low-dimensional, interpretable representations of 3-D geological structures. Combining these models with geophysical data in a probabilistic joint inversion framework provides an opportunity to directly quantify
uncertainty in geological interpretations. For best results, care must be taken with the intermediate step of rendering parametric geology in a finite-resolution discrete basis for the geophysical calculation. Calculating geophysics from naively voxelized geology, as exported from commonly used geological modeling tools, can produce a poor approximation to the true likelihood, degrading posterior inference for structural parameters. We develop a simple integrated Bayesian inversion code, called
Blockworlds, showcasing a numerical scheme to calculate anti-aliased
rock properties over regular meshes for use with gravity and magnetic sensors. We use Blockworlds to demonstrate anti-aliasing in the context of an implicit model with kinematic action for simple tectonic histories, showing its impact on the structure of the likelihood for gravity anomaly.
ENVIRONMENTAL IMPLICATION OF WOODEN CASKET PRODUCTION ON AMBIENT AIR QUALITY IN PART OF OWERRI MUNICIPAL, SOUTH EASTERN NIGERIA
Authors: Ubuoh E.A , Nwogu F.U. , Biose E 
Published: May 2022

The study assessed the effect of wooden casket production on air quality at old market road in Owerri South Eastern Nigeria. The study was carried out in October, 2019, during morning, afternoon and evening periods of the day respectively. Priority air quality parameters sampled included: SO2, PM10, CO, NO2, TVOC, H2S, HCN and Cl2 alongside climatic variables at graded distances. Outdoor air quality was measured by digital air monitors hourly. Data collected were analyzed using ANOVA, SPSS v.20 software, and mean values separated using Duncan at p<0.05 significant level. Results were compared to Environmental standards, Air Quality Index (AQI) and Pollutant Standard Index (PSI). Ambient air qualities were significantly different (p<0.05) at the various distances except for PM10, SO2, CO, NO2, VOC, H2S, HCN and Cl2 which were all above the standards for clean air, describing the area as non-attainment spot. Temperature, relative humidity and wind speed were recorded in the mean values of 31.6oC, 91.6%, and 0.2m/s respectively. The result ranged in order of abundance: afternoon (A)>evening (E)>morning (M) respectively. Air quality rating ranged between poor - D (PM10) to very poor - E (CO, NO2, SO2), implying the poor stage of atmospheric air in the study area. The mean results of the PSI showed that PM10 ranged from 133.96±0.75 - 138.5±1.25µg/m3, CO ranged from 183.25±1.2 - 297.59±6.47ppm while VOC ranged from 124.08±0.27-127.36±0.42ppm that fall within unhealthy and very unhealthy respectively. The results suggest that relocation of the industry and awareness creation on the use of Personal Protective Equipment (PPEs) by casket workers to avert occupational health hazards at work.
Reflexões sobre o papel da educação física enquanto área de linguagens e sua tecnologias para o novo ensino médio à luz da BNCC
Authors: Pereira Leite Francisco Edson , Da Costa Barros João Luiz 
Published: May 2022

Este ensaio foi escrito no decorrer da disciplina Linguagem, Educação e Relações com o Saber do Programa de Pós Graduação Doutorado em Educação em Rede – PEGEDA/Educanorte-UFAM. Focamos nosso discurso no componente curricular Educação Física e traçamos como objetivo analisar o seu papel na área de Linguagens e suas Tecnologias para o Novo Ensino Médio considerando as exigências da Base Nacional Comum Curricular (BNCC). O texto foi produzido a partir de uma pesquisa de revisão bibliográfica sobre a Educação Física Escolar, o Novo Ensino Médio e a BNCC. Nossas análises indicam que a Educação Física tem o papel de formar sujeitos éticos, conscientes e defensores dos direitos humanos e dos valores democráticos, capazes de adotar estratégias e possibilidades de utilização dos espaços públicos e privados de lazer de forma saudável e inclusiva. Para tanto compete ao professor de Educação Física orientar as mais diversas práticas corporais, estimular a pesquisa, análise e reflexão sobre o uso da Cultura Corporal de Movimentos. Sendo também responsável pela ampliação dos conhecimentos sobre as potencialidades e os limites do corpo, ajudando na compreensão sobre a importância de se assumir um estilo de vida ativo, e os componentes do movimento relacionados à manutenção da saúde, promovendo o autoconhecimento e o autocuidado.
A Política de Atendimento Educacional Especializado (AEE) para surdos no município de Igarapé-Miri/PA: contribuições e limitações
Authors: Costa Eduarda Gonçalves da , Melo Rosileide de Jesus de Souza , Souza Alexandre Augusto Cals e 
Published: May 2022

O presente trabalho tem como objeto de estudo o Atendimento Educacional Especializado - (AEE). O objetivo geral se concentra em compreender as contribuições e limitações do atendimento educacional especializado no ensino inclusivo dos alunos surdos no município de Igarapé-Miri/PA, a partir da ótica de dois sujeitos. Para isso, a pesquisa segue uma abordagem qualitativa (OLIVEIRA,2007), constituindo-se primeiramente em uma pesquisa bibliográfica e em um estudo de caso (GIL,2008), por se tratar de uma situação específica, sendo realizado entrevista com duas pessoas surdas. Adotamos como referencial teorico, os estudos de autores que tratam da educacão especial de Surdos, assim como do AEE, a saber, Mantoan(2003), Gesser(2009), Sartoretto(2010), Sá(1999) e BRASIL(20001, 2008, 2015 e 2018). Os resultados da pesquisa demonstram a insatisfações com a eficiência do AEE, em relação ao ensino de surdos, os quais decorrem da falta de domínio da Libras e da não execução políticas e diretrizes para atuação desse profissional.
Saúde mental e COVID-19: sentimentos vivenciados por gestantes em tempos de pandemia
Authors: Boeck Gabriele Avellar , Carvalho Bárbara Luiza Rodrigues , Back Ivi Ribeiro , Santos Aliny de Lima 
Published: May 2022

Objetivo: conhecer as percepções maternas acerca do processo gestacional no decorrer da pandemia do COVID-19 e suas repercussões na saúde mental. Método: estudo descritivo, de natureza qualitativa, realizado com 10 gestantes no estado do Paraná, Brasil, entre julho e novembro de 2021, mediante entrevistas semiestruturadas submetidas à análise de conteúdo, modalidade temática. Resultados: emergiram quatro categorias: vivências emocionais com a descoberta da gestação durante a pandemia; reflexos da pandemia no cuidado durante o período gestacional; alteração na dinâmica das atividades laborais das gestantes, no contexto do isolamento; reconhecendo a importância do apoio familiar no ciclo gravídico-puerperal. Considerações finais: evidenciou-se uma relação direta entre o contexto pandêmico e os sentimentos apresentados pelas futuras mães. Fatores como a restrição de acompanhantes, isolamento social, alteração da dinâmica laboral, medo de transmissão da doença e de suas possíveis complicações, favorecem a incidência de ansiedade, medo, solidão e insegurança. Notou-se que a rede de apoio familiar viabiliza suporte emocional às gestantes em meio às preocupações vivenciadas com a pandemia.
Nano-Liposomal Encapsulation-Delivered Apelin-13 Attenuates Ev71 Infection-Induced Neurodegeneration by Modulating Il-6 and Tlr7
Authors: Xu Shengnan , Cui Cheng , Sun Manchao , Guo Sihui , Xu Ke , Cui Yanan , Gao Ziyin , Wu Zhenqi , Xue Jiaxin , Ma Yucai , He Xue , Cai Guofeng 
Published: May 2022

Background:
Enterovirus 71 (EV71) infection serves as a leading cause of hand-foot-and-mouth disease, and induces neural disorders. Apelin-13, as a neuropeptide, presents potential neuroprotective activities, but its short half-life in circulation has limited its clinical use.

Objective:
To explore the role of nano-liposomal encapsulation-delivered apelin-13 in the development of EV71 infection-induced neurodegeneration.

Method:
The liposome encapsulating apelin-13 (lipoPEG-A13) was successfully constructed and characterized in the study. The neurodegeneration measurement in an intracranially EV71-infected mouse model was performed in vivo. MTT assays, lactate dehydrogenase release assays, immunohistochemistry, and immunofluorescence staining qPCR assays, and Western blot analysis were respectively performed.

Results:
EV71 notably replicated and promoted apoptosis in the cerebral cortex from the EV71-infected mice but exhibited comparatively low replication and slightly regulated apoptosis in the cerebellum. Remarkably, lipoPEG-A13 was able to inhibit EV71-induced neurological injury in the murine cerebral cortex in vivo. Meanwhile, LipoPEG-A13 could attenuate EV71-caused apoptosis of the neural cell in the brain. LipoPEG-A13 decreased the Toll-like receptor 7 (TLR7) and interleukin-6 (IL-6) production in the mice. Apelin-13 inhibited the expression of TLR7 and IL-6 in the human astroglioma U251 cells. Apelin-13 could reduce the apoptosis of astrocytic cells infected with EV71.

Conclusion:
Nano-liposomal encapsulation-delivered apelin-13 attenuated EV71 infection-induced neurodegeneration via modulating IL-6 and TLR7 production. The finding provides new insights into how Nano-liposomal encapsulation-delivered apelin-13 modulates EV71 infection-induced neurological disorders. The Nano-liposomal encapsulation-delivered apelin-13 presents the application potential in the clinical context.
Reframing Ethical Theory, Pedagogy, and Legislation to Bias Open Source AGI Towards Friendliness and Wisdom
Authors: Cox John Gray 
Published: May 2022

Hopes for biasing the odds towards the development of AGI that is human-friendly depend on finding and employing ethical theories and practices that can be incorporated successfully in the construction, programming and/or developmental growth, education and mature life world of future AGI. Mainstream ethical theories are ill-adapted for this purpose because of their mono-logical decision procedures which aim at “Golden rule” style principles and judgments which are objective in the sense of being universal and absolute. A much more helpful framework for ethics is provided by a dialogical approach using conflict resolution and negotiation methods, a “Rainbow rule” approach to diversity, and a notion of objectivity as emergent impartiality. This conflict resolution approach will also improve our chances in dealing with two other problems related to the “Friendly AI” problem, the difficulty of programming AI to be not merely smarter but genuinely wiser and the dilemmas that arise in considering whether AGIs will be Friendly to humans out of mere partisanship or out of genuine intent to promote the Good. While these issues are challenging, a strategy for pursuing and promoting research on them can be articulated and basic legislation and corporate policies can be adopted to encourage their development as part of the project of biasing the odds in favor of Friendly and Wise AGI.
Key trends in the development of mechanical engineering in Ukraine
Authors: Sozanskyy Lyubomyr , Koval Liudmyla 
Published: May 2022

The article presents an analysis of the state of and trends in the Ukrainian mechanical engineering industry based on selected key economic indicators. The industry is characterised by unstable, negative dynamics and falling production volumes, a rapid decrease in the volume and share of implemented innovative products, a significant reduction in the number of manufactured motor vehicles, an insignificant volume of high-tech products, a reduction in capital investments and a high level of depreciation of fixed tangible assets, extremely low labour productivity, a rapid decline in the number of employed workers, relatively low wages, a deterioration of the external balance. The authors view the current economic trends as destructive systemic changes that can significantly affect not only the activity of the machine-building industry but of the country as a whole. They highlight the critical state of the domestic mechanical engineering industry caused by a long period of inaction on the part of the state as regards the development of this industrial sector, which is only exacerbated by the military and hybrid aggression of the Russian Federation against Ukraine. The authors propose ways of overcoming these negative tendencies.
Cryptocurrencies in the COVID-19 era
Authors: Marecki Krzysztof , Wójcik-Czerniawska Agnieszka 
Published: May 2022

The purpose of the article is to describe the state of the financial market during and after the COVID-19 pandemic. The financial environment is facing new questions about the future, one of which concerns the role played by cryptocurrencies in the coming years. In recent years the cryptocurrency market has been experiencing spectacular growth, with more than 5,500 cryptocurrencies now in existence worldwide. They can either be used as safe haven currencies that provide protection against market volatility or as a payment system with the prospect of consolidation. Whatever the case may be, the pandemic circumstances favour the development of these digital assets. The crisis generated by the pandemic has also affected the value of bitcoin, which has been quite volatile. While it seems to be recovering, the near future is uncertain. The uncertainty brought about by the coronavirus health crisis has caused a general collapse in the stock markets. In this context, the authors review the behaviour of bitcoin, with its dips and recoveries, which can occur in a matter of a few hours. The first months of national lockdowns were mainly marked by social issues. When social distancing has become the norm, cryptocurrencies can play a bigger role than they did previously, driving the evolution of money away from cash in the direction of cashless society.
Modern global trends regarding the requirements for managerial competences
Authors: Pasinovych Iryna 
Published: May 2022

The article outlines the main objectives of modern management, such as the need to ensure the stability of companies or the formation of corporate culture, taking into account the principles of behavioral economics. The author highlights the growing importance of a systemic approach and democratization in management and identifies the key global trends that affect the way companies are managed. These include globalization, the focus on sustainable development, VUCA conditions, rapid technological development, changes in the nature of office and managerial work. A comparative description of industrial and post-industrial society is given to show that human capital has become a key resource while knowledge is the driving force of development. Taking into consideration these new requirements, the authors identifies the key competencies of a modern manager.
Evaluation of the Safety of Ketorolac in Postsurgical Infants Less Than Six Months of Age
Authors: McElroy Nicole A. , Bustin Anna , Gattoline Sarah 
Published: May 2022

OBJECTIVE
Ketorolac-related adverse events are not yet elucidated in neonates and infants given paucity of data. The objective of this research is to determine the incidence of major bleed in postsurgical neonates and infants treated with ketorolac, and to describe characteristics of ketorolac therapy and its effect on renal function.

METHODS
This retrospective review assessed postsurgical patients younger than 6 months of age, without renal and/or coagulation dysfunction, who received ketorolac for postoperative pain during the study period. Major bleed was defined as a decrease in hemoglobin by ≥ 2 g/dL in a 24-hour period and/or intracranial, intraventricular, gastrointestinal, or pulmonary hemorrhage. Renal injury was identified per pediatric-modified RIFLE (risk, injury, failure, loss, end stage renal disease) criteria.

RESULTS
One hundred twenty-five patients were analyzed, having a mean dosing weight of 5.6 kg, gestational age of 37.2 weeks, and postnatal age of 3.8 months. Ketorolac therapy was most frequently 0.5 mg/kg intravenously every 6 hours with a mean of 6.7 doses administered. The primary endpoint of major bleed occurred in 2 (1.6%) 2-month-old patients of 39 weeks' gestation. Both bleeds were characterized by decrease in hemoglobin without evidence of clinically significant bleeding. One (0.8%) and 3 (2.4%) patients experienced a decrease in glomerular filtration rate and urine output, respectively. Sixty-two (49.6%) patients received a concomitant medication associated with decreased bleeding risk.

CONCLUSIONS
Ketorolac appears to have low incidence of major bleeds in postsurgical patients younger than 6 months of age without renal and/or coagulation dysfunction. Larger, prospective studies are needed to confirm safety of ketorolac use in this population.
Methylnaltrexone in the Management of Opioid-Associated Urinary Retention in Children
Authors: Suchovsky Skyler B. , Reiter Pamela D. , Lewis Hannah E. , Clevenger Amy C. 
Published: May 2022

OBJECTIVE
To evaluate the association between methylnaltrexone and urine output (UOP) in critically ill children with opioid-associated urinary retention.

METHODS
This retrospective study included patients admitted to the pediatric intensive care unit between December 1, 2019, and November 30, 2020, who received methylnaltrexone for opioid-associated oliguria (spontaneous UOP below 1 mL/kg/hr and at least 1 dose of an opioid within the preceding 6 hours).

RESULTS
Twenty-five patients (median age = 5.5 years, IQR 1.7–16.4; median weight = 19 kg, IQR 9–45) were included. Mean methylnaltrexone dose was 0.15 ± 0.006 mg/kg. A statistically significant increase in UOP from baseline to 6 hours following methylnaltrexone was observed (p = 0.001), but not all patients responded. Fourteen patients (56%) had no UOP following methylnaltrexone administration, while 11 (44%) demonstrated a robust increase (median = 0 mL/kg/hr at baseline [IQR 0–0] to 1.96 mL/kg/hr [IQR 1.08–2.22; p = 0.001]) within 6 hours following methylnaltrexone administration. Younger patients responded better than older patients (responder age = 2.5 years [IQR 0.8–7]) versus 11.4 years [IQR 1.75–17.5] for non-responders) (p = 0.04). Both intravenous (IV) and subcutaneous (SQ) routes were associated with an increase in UOP (IV, p = 0.04; SQ, p = 0.02). The effect persisted for up to 24 hours after administration. Sixty-four percent of patients required urinary catheter placement. Pain scores (averaged 6 hours before and after methylnaltrexone) remained unchanged (p = 0.44).

CONCLUSIONS
Methylnaltrexone may increase spontaneous UOP in some children with opioid-associated urinary retention, but urinary catheterization rates remain high.
Alzheimerpårørende i møte med omgivelsene
Authors: Lyngsnes Kitt Margaret 
Published: May 2022

Over 100 000 personer i Norge lever med demens. En liten gruppe av disse er diagnostisert før fylte 65 og er dermed i kategorien «yngre med demens». Målet med studien presentert i denne artikkelen, er å utforske ett aspekt av å være pårørende når ens ektefelle har fått en Alzheimerdiagnose i ung alder. Problemstillingen setter søkelyset på å være pårørende og stå i en situasjon preget av omsorg og sorg og samtidig forholde seg til omverdenens spørsmål og innspill vedrørende en slik progredierende, uhelbredelig sykdom. Forskningstilnærmingen er autoetnografisk, og det empiriske materialet består av erfaringer som er opplevd og analysert gjennom en periode på flere år. Et hovedfunn i studien er betydningen av å reflektere over pårørendeerfaringer både alene og sammen med andre. Derigjennom kan en bli bevisst egne reaksjoner og emosjoner og utvikle innsikt og strategier en som pårørende i en krevende omsorgssituasjon kan møte andre med, samtidig som en kan ivareta egne følelser.
Knowledge and Attitude Level of the MGNREGA Respondents in Nalanda District of Bihar
Authors: Chandra Vineeta , Mazhar Syed H. 
Published: May 2022

Population wise Bihar is third populated state in India. In the state more than 85% of population stays in rural area and the state is the least urbanized state of the country and have a low source of income which leads to increase in poverty. National Rural Employment Guarantee Act 2005 (or, NREGA, later renamed as the “Mahatma Gandhi National Rural Employment Guarantee Act”, MGNREGA), is an Indian labour law and social security measure that aims to guarantee the ‘right to work’. The present study aims to analyse the knowledge and attitude level of MGNREGA respondents. The study was conducted in Nalanda district of Bihar which was selected purposively as the MGNREGA scheme is currently running in the district. Hilsa block was selected by purposive sampling for the study as the block has the largest number of MGNREGA beneficiaries. Total six villages were selected for the study by purposively considering the fact that these villages have greater number of MGNREGA beneficiaries. A total of 120 respondents were taken randomly. The data were collected by pre- structured interview schedule and appropriate statistical analysis was done to find out the meaningful results. The finding of the study reveals that the majority (47.50 per cent) of the respondents had medium level of knowledge about MGNREGA scheme followed by 32.50 per cent and 20 per cent of the respondents having high and low level of knowledge, respectively. It also reveals that 40 per cent of the respondents had medium level of attitude of MGNREGA scheme followed by 33.33 per cent and 26.67 per cent of the respondents having high and low level of attitude.
Determination of Essential Mineral Content of Maize (Zea mays L.) Produced and Stocked from Rural Conditions in Côte d’Ivoire
Authors: Désiré Kouamé , Léonce Niamketchi Gilles , Constant Konan , Ysidor Konan , Marius Biego Henri 
Published: May 2022

Aims: Maize (Zea mays) is a staple food in the traditional diet of rural populations in Cote d'Ivoire. It is a good source of nutrients. However, sometimes inefficient storage methods hamper its quality. It’s in this context that this study was conducted to assess the essential mineral content of maize produced and stored in five regions of Côte d’Ivoire.
Study Design: A total of 1500 samples of maize as grains, epis and spathes were collected at rate of 500 samples by region (Gbêkê, Poro, Hambol, Indénié-Djuablin and Gontougo) and sent to the laboratory in order to analyse their mineral’s composition.
Place and Duration of Study: This study was carried out during March 2016 to January 2017. The collected samples were carried out at the Biochemistry and Food Sciences Laboratory of the Félix Houphouët-Boigny University, Abidjan.
Methodology: The determination of minerals was carried out using the energy dispersive spectrophotometry method.
Results: The results show a significant difference (P<0.001) between mineral contents of the different maize forms and regions. The average values are between: K (289.99±28.98-324±4.07 mg/100 g), P (256.98±28.99-302.1±3.10 mg/100 g), Na (46.08±15.08-63.87±4.09 mg/100 g), Ca (40.08±26.97 to 51.20±3.89 mg/100 g), Mg (100.78±4.89-111±2.08 mg/100 g) for macroelements and Fe (3.08±3.00-5.02±1.08 mg/100 g), Zn (3.78±3.00-5.20±0.47 mg/100 g), Cu (1.00±0.60-1.42±0.02 mg/100 g), Mn (0.68±0.52-1.01±0.03 mg/100 g), Se (0.05±0.01-0.25±0.04 mg/100 g) for oligoelements.
Conclusion: Maize grains have the highest contents of mineral element from overall samples except for selenium (Se). Oppositely, samples from Indénié-Djuablin and Gontougo regions showed lowest concentrations. Therefore, mineral content of maize sampled seems to be related to post-harvest treatments (drying), type of storage (grains, epis and spathes) and storage structure.