bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE ROLE OF SKIN CARE PRODUCTS AND EARLY FOOD FOR THE PREVENTION OF ATOPIC DERMATITIS IN INFANTS
Authors: Mozyrska O.V. , Slyusar N.A. 
Published: December 2022

The aim of the study
The aim of this study was to assess the value of interventions aimed at improving the skin barrier and skin care products, as well as breastfeeding and early introduction of complementary foods, for the primary prevention of atopic dermatitis (AD) and food allergy in infants.
Materials and methods
We started a survey in the period from May 2022, which continues to this day. The survey was conducted with the help of Google forms and distributed on the Internet, as well as parents of children who applied for help at Kyiv children’s clinical hospital No. 2 and MC "Allergolog" were interviewed. The relationship between intervention methods and the development of AD and food allergy was determined using the odds ratio (OR) with a 95% confidence interval (CI).
Results
According to the survey data, 42,2% of children received moisturizing cream, parents of 16,5% of children reported using moisturizing oil for bathing the child, 12,4% of parents used less soap and bathed the child less often, 28,9% reported that they did not use none of these methods and means of care.
AD occurred in 23,7% of children interviewed. The odds ratio for the moisturizing cream group was 68,6 (CI 3,9-1201,5), p=0,004, for the groups that used moisturizing oils for bathing – 8,9 (CI 0,4-197,6), p= 0,17, for the group where the intervention was a reduction in bathing and using soap – 7,1 (CI 0,3-186,0), p=0,24.
18,6% of respondents reported a reaction to food that occurred in the child within 2 hours after consumption. We have not found any role of emollients (OR=1,4, CI 0,4-4,9), p=0,56, moisturizing oils for bathing (OR=0,3, CI 0,03-2,6), p=0,27, and reduced use of soap and water (OR=1,4 (CI 0,3-7,2), p=0,66 for the development of food allergy.
The duration of breastfeeding (more than 3 months) did not affect the risk of developing AD (OR = 0,1, CI 0,01-2,6), p = 0,19, or food allergy (OR = 1,3, CI 0,3-6,9), p=0,74. Also, the role of earlier introduction of supplementary food on the development of AD and food allergy was not shown: the OR for AD was 0,9 (CI 0,3-2,7), p=0,8, the OR for food allergy was 0,8 (CI 0,2- 2,9), p=0,76.
Conclusions
This study did not reveal the protective role of skin care products, breastfeeding, and early introduction of complementary foods for the development of AD and food allergies in children. A larger survey will allow us to study the effect of emollients and other preventive measures on the development of food allergies in a group of children with AD.
Application of Structural Retinal Biomarkers to Detect Cognitive Impairment in a Primary Care Setting
Authors: Mozdbar Sima , Petersen Melissa , Zhang Fan , Johnson Leigh , Tolman Alex , Nyalakonda Ramyashree , Gutierrez Alejandra , O’Bryant Sid 
Published: December 2022

Background: Despite the diagnostic accuracy of advanced neurodiagnostic procedures, the detection of Alzheimer’s disease (AD) remains poor in primary care. There is an urgent need for screening tools to aid in the detection of early AD. Objective: This study examines the predictive ability of structural retinal biomarkers in detecting cognitive impairment in a primary care setting. Methods: Participants were recruited from Alzheimer’s Disease in Primary Care (ADPC) study. As part of the ADPC Retinal Biomarker Study (ADPC RBS), visual acuity, an ocular history questionnaire, eye pressure, optical coherence tomography (OCT) imaging, and fundus imaging was performed. Results: Data were examined on n = 91 participants. The top biomarkers for predicting cognitive impairment included the inferior quadrant of the outer retinal layers, all four quadrants of the peripapillary retinal nerve fiber layer, and the inferior quadrant of the macular retinal nerve fiber layer. Conclusion: The current data provides strong support for continued investigation into structural retinal biomarkers, particularly the retinal nerve fiber layer, as screening tools for AD.
Konflik Sosial Dalam Novel Tan Karya Hendri Teja Melalui Teori Konflik Lewis A. Coser
Authors: Andriyana Dede Nova , Mubarok Zaky 
Published: December 2022

This study aims to describe the social conflicts that occur in the novel Tan by Hendri Teja. This research is descriptive research. The object of this research is about social conflicts that occur in novels based on social conflicts according to Lewis A. Coser. These conflicts include realistic conflicts, non-realistic conflicts and positive functions of social conflicts. The data in this study were obtained by analyzing Tan's novel by Hendri Teja using reading and note-taking techniques. the results of this study indicate that there are social conflicts in Tan's novel by Hendri Teja. Realistic conflicts in Tan's novel are arguments, quarrels and differences in views and differences in interests. Non-realistic conflict in the novel is a conflict that aims to relieve tension, at least from one party. And the positive function of social conflict is a way that is taken to maintain, unite, and even to reinforce existing social systems, both individuals and groups or groups. Keyword: Social Conflict, Conflict functionalism, Literary Sociology.
Peranan Perencanaan Pekerjaan dan Analisis Pekerjaan Terhadap Tujuan Organisasi Perusahaan/Instansi
Authors: Sunandar Darwis , Rohmalia Yuli , Saleh Arif Rahman , Sukarsih Cicih , Ramly Amir Tengku 
Published: December 2022

<p>Peranan perencanaan pekerjaan dan analisis pekerjaan terhadap tujuan organisasi perusahaan/instansi mempunyai peran yang sangat penting. Penelitian ini bertujuan untuk mengetahui peranan perencanaan sumberdaya manusia dan analisis pekerjaan terhadap keberhasilan organisasi perusahaan/instansi. Metode penelitian menggunakan <em>literature review. </em>Hasil penelitian menunjukan bahwa peran perencanaan sumberdaya manusia yang terdapat pada jurnal hasil <em>review</em>, yaitu untuk menentukan kualitas dan kuantitas karyawan yang akan mengisi semua jabatan dalam perusahaan, untuk menghindari terjadinya mismanajemen dan tumpang tindih dalam pelaksanaan tugas dan untuk mempermudah koordinasi, integrasi, dan sinkronisasi (KIS) sehingga produktivitas kerja meningkat. Sedangkan peran analisis pekerjaan yaitu untuk memperoleh tenaga kerja pada posisi yang tepat, untuk memberikan kepuasan pada diri tenaga kerja dan untuk menciptakan iklim dan kondisi kerja yang kondusif. Peran perencanaan sumberdaya manusia dan analisis pekerjaan yang baik, mengakibatkan tujuan organisasi perusahaan/instansi menjadi lebih mudah tercapai, demikian pula sebaliknya</p>
Pengaruh Pandemi Covid19 Terhadap Omzet UMKM Keripik Pangsit di Kelurahan Kertamaya Kota Bogor
Authors: Firdaus Ali 
Published: December 2022

<p>Saat ditetapkannya Covid19 pada tanggal 11 Maret 2020 sebagai pandemi, yang secara cepat melanda dunia, termasuk pula Indonesia dan sampai pada Pemerintah terbawah yakni Desa/ Kelurahan, hal ini mengakibatkan masyarakat untuk senantiasa berdiam dirumah, dengan mengurangi segala aktifitas kesehariannya atau bahkan sampai di <em>lockdown </em> guna membantu upaya Pemerintah dalam mencegah dan menangani penyebaran Covid19 yang sangat meluas ini, yang sampai dengan saat ini belum dapat terselesaikan, sehingga tidak hanya berpengaruh dari segi kesehatan juga secara ekonomi sampai terasa kepada pelaku UMKM terbawah seperti halnya usaha keripik pangsit yang tersebar di Kelurahan Kertamaya Kecamatan Bogor Selatan Kota Bogor mengalami penurunan Omzet. Penelitian ini bertujuan untuk dan menganalisis sejauh mana pengaruh pandemi covid-19 terhadap pelaku UMKM keripik pangsit yang ada di Kelurahan Kertamaya Kecamatan Bogor Selatan Kota Bogor. Metode penelitian yang digunakan adalah metode deskriptif kualitatif, dengan menggunakan sumber data sekunder dari hasil penelitian, referensi dan berita <em>online </em>yang terkait langsung dengan penelitian ini.</p>
manajemen laba terhadap kinerja keuangan dengan pengungkapan CSR sebagai variabel moderasi
Authors: Rosmawati  
Published: December 2022

Setiap kompetisi tidak menutup kemungkinan adanya praktik memanipulasi data yang dilakukan manajer (manajemen laba). Maka perlunya suatu penelitian untuk mengetahui dampak manajemen laba dan Corporate Social Responsibility terhadap kinerja perusahaan tersebut. Tujuan Penelitian ini adalah untuk mengukur pengaruh variabel independen (bebas), dependen (terikat), dan dimoderasi yang dilakukan dalam pengujian menggunakan program SPSS for Windows 20.
Hasil regresi yang diperoleh pada model pertama memperoleh signifikansi sebesar 0,125 (tidak signifikan) sedangkan pengungkapan CSR memperoleh tingkat signifikansi 0,002 (signifkan) dan untuk model ke tiga variabel interaksi (DAC*csri) menunjukan nilai signifikansi 0,743 artinya tidak signifikan. Hasil ini menunjukan bahwa variabel terukur dalam hal ini variabel pengungkapan CSR tidak dapat memoderasi pengaruh variabel manajemen laba melainkan dapat diberlakukan sebagai variabel predictor (independen).
THREECLE MODEL: PENERAPAN KEPEMIMPINAN DI PRIMEBIZ HOTEL SURABAYA
Authors: Anshori Mohamad Yusak 
Published: December 2022

Primebiz Hotel Surabaya (PBS) is service company (hotel) which its service quality is determined by its human resources. The quality of its human resource much be influenced by hotel leader. Leadership has an important role in the company since leadership will influence the management style, corporate culture, working environment, and values of the company. To resolve human resources management problems, it uses threecle (three circle) model. This model was shaped from the practical management that has been implemented at Primebiz Hotel Surabaya (PBS). In this study, various leadership models are elaborated and discussed at the PBS. The result of the implementation of this model much support the hotel management in making decision and increasing the efficiency as well as the effectiveness in the hotel operation. Implementing this model, it means increasing wisdom and fairness in making decision, especially related with the human resources issues.
Kuckuck in den Glaubensvorstellungen der Saamen
Authors: Bartens Hans-Hermann 
Published: December 2022

The desire to be able to look into the future and thus be prepared for what it holds, can be achieved, according to folk beliefs, by observing animals, including birds. The Saami materials scrutinized for this work mention approximately sixty different bird species which have some kind of function as an omen. The most important among them is the cuckoo, both as far as the number of mentions is concerned as well as its diffusion throughout the Saami area, which, however, does not appear to extend to the easternmost traditional areas. This observation also applies to the other bird species. As birds also hold this function in Scandinavian and Finnish tradition, the postulate that we are dealing with a shared tradition seems justified. A systematic comparison of the distinct traditions is not the aim of this paper. Nevertheless, the comparisons made reveal common features among which, however, aspects specific to the Saami area can be discerned.
The cuckoo has traditionally been one of the most feared birds. Its relationship with humans was mostly unidirectional: the cuckoo is in command while man is exposed to the magical powers of the bird. Folklore holds information on how to undo this harmful influence; in addition to warnings, there are concrete recommendations on how to counter it. There are also tales of humans simply being exposed to such influence. The harm done usually affected daily chores, but especially in the northern Saami region it could impact on a personʼs very life. Nonetheless, there are also examples of a positive relationship between bird and man such as the cuckoo’s tree. In this specific tradition, the cuckoo is again in charge, but there is genuine interaction between man and the animal.
Propuesta para elaboración de bases concentradas a partir de cebolla excedente de la producción panameña
Authors: Rohim-Domínguez Carolle , Ayala-Valdés Adrián , Luzcando-González Ana , Broce Kathia , Cedeño Cristel 
Published: December 2022

En la búsqueda de mejorar diferentes aspectos de vida; acceder a alimentos sanos y cada vez más naturales, así como conformar sistemas de comercio alternativos, se hace necesario para el desarrollo sostenible. Durante el periodo agrícola 2020-2021, la producción de cebolla nacional alcanzó los 484,255 quintales, un aumento de 54.3% comparado con el periodo anterior (2019-2020), según cifras de la Dirección de Agricultura del Ministerio de Desarrollo Agropecuario en Panamá. Este trabajo tiene como objetivo elaborar una propuesta viable de un producto innovador, bases concentradas, utilizando la cebolla de producción panameña. Para el desarrollo de estas bases concentradas se realizó la formulación, el diseño del proceso, determinación de parámetros fisicoquímicos, elaboración del etiquetado nutricional y análisis sensorial. Los resultados muestran que las bases concentradas preferidas por el panel sensorial fueron la base concentrada de cebolla ahumada y ajo y la base concentrada de sofrito panameño. En cuanto a los parámetros fisicoquímicos se encuentra diferencia en los resultados de pH, Aw, ° Brix y viscosidad esto para la base concentrada de cebolla ahumada y ajo y la base concentrada de sofrito panameño, esto debido a la inclusión de pasta de tomate y achiote a la base concentrada de sofrito panameño. En conclusión, la utilización de la cebolla como ingrediente principal logró resaltar a nivel sensorial, esto debido a la utilización de transformaciones asociadas al proceso de ahumado.
Situación actual de la aplicación y potenciales usos de la visión artificial en la entomología agrícola en Panamá
Authors: Atencio Randy , Cruz Edmanuel 
Published: December 2022

Variables como el cambio climático, las sequías, los huracanes, la deforestación y el uso indiscriminado de plaguicidas desencadenan constantemente la presencia de insectos plagas en el país, así como de potenciales plagas invasoras que encuentran las condiciones necesarias para establecerse y causar daños en los cultivos sensibles del país. La entomología agrícola se centra en el estudio de los insectos asociados a las plantas relacionadas con la agricultura, tanto los perjudiciales como los beneficiosos, dando cada vez más importancia al medio ambiente y apoyándose en los avances biotecnológicos disponibles para conservar y aumentar la biodiversidad en las zonas agrícolas. Por otra parte, hay una serie de nuevas tecnologías que pueden utilizarse en la entomología agrícola, como la visión artificial. La visión por ordenador o visión artificial es el área de investigación en torno a cómo los ordenadores ven y entienden las imágenes digitales y/o videos. Este estudio pretende dar un enfoque de la situación actual y potenciales usos de la visión por ordenador en la entomología agrícola y examinar de manera puntual cómo puede aplicarse en Panamá. Se evalúa los retos y las técnicas de visión por ordenador e inteligencia artificial aplicadas a la entomología mediante la selección de bibliografía actual publicada sobre la temática. Asimismo, este trabajo pretende identificar las lagunas y las oportunidades con vistas a convertirse en una referencia actualizada para futuros trabajos. Se analizaron varias referencias bibliográficas, de los cuales se extrajo la información contenida y se expone la aplicabilidad de las distintas técnicas en Panamá.
Tracing the Innovation – Decision Process for Adopting Microchip Implants: Reflections and Experiences of Estonian Employees
Authors: Siibak Andra , Otsus Marleen 
Published: December 2022

Relying on the diffusion of innovations theory by Everett Rogers (1962 [2003]), the current paper traces the five steps of the innovation-decision process for adopting microchip implants in a workplace. Semi-structured individual interviews with microchipped employees (n=14) from six different organisations in Estonia were carried out to explore their opinions and experiences with adopting the use of microchip implants in their workplaces.Our analysis indicates that social reinforcement from their colleagues played an important role in the formation of the attitudes and beliefs of our interviewees about microchip implants. In fact, a strong element of homophily existed within the social system both on the organisational and interpersonal levels. Our findings suggest that the employees who decided to get microchip implants were considered to be more loyal and dedicated, as well as more in sync with the overall goals and values of the organisation; the employees who rejected the innovation were viewed as less motivated and not as invested in their organisations. All our interviewees stressed that they were voluntary adopters of the innovation and wholeheartedly believed in the value of trade-offs between convenience and privacy.
Placental stem cells-derived exosomes stimulate cutaneous wound regeneration via engrailed-1 inhibition
Authors: Zhang Yan , Shi Liyan , Li Xiuying , Liu Yang , Zhang Guokun , Wang Yimin 
Published: December 2022

Introduction: Skin wounds generally heal by scarring, a fibrotic process mediated by the Engrailed-1 (EN1) fibroblast lineage. Scar is detrimental to tissue structure and function, but perfect healing in clinical settings remains to be explored. Recent studies have shown that mesenchymal stem cell (MSC) transplantation can reduce scarringMethods: Here, we investigated the effects of placental MSCs (pMSCs) and exosomes derived from pMSCs (pMSC-exos) on wound healing using a full-thickness rat model.Results: The results showed that placental MSCs significantly accelerated the wound healing rate. Moreover, placental MSCs improved the quality of wound healing, including regenerating cutaneous appendages (hair follicles and sebaceous glands), decreasing collagen I and increasing collagen III, and improving collagen pattern (basket-wave-like) in the healed skin. placental MSCs treatment also increased the regeneration of blood vessels. Importantly, all these listed effects of placental MSCs were comparable to those of exosomes derived from pMSCs, but significantly stronger than those of adipose MSC-derived exosomes (aMSC-exos). Further studies showed that the effects of placental MSCs and exosomes derived from pMSCs on wound regeneration may be mainly achieved via the down-regulation of the Yes-associated protein signaling pathway, thus inhibiting the activation of EN1. Discussion: In summary, placental MSCs could effectively stimulate wound regeneration, and their effect could be achieved through their exosomes. This suggests that exosomes derived from pMSCs treatment could be used as a novel cell-free approach to induce wound regeneration in clinical settings.
Evaluation of geographically weighted logistic model and mixed effect model in forest fire prediction in northeast China
Authors: Zhang Zhen , Yang Song , Wang Guangyu , Wang Weiwei , Xia Hongtao , Sun Shuaichao , Guo Futao 
Published: December 2022

IntroductionForest fires seriously threaten the safety of forest resources and human beings. Establishing an accurate forest fire forecasting model is crucial for forest fire management.MethodsWe used different meteorological and vegetation factors as predictors to construct forest fire prediction models for different fire prevention periods in Heilongjiang Province in northeast China. The logistic regression (LR) model, mixed-effect logistic (mixed LR) model, and geographically weighted logistic regression (GWLR) model were developed and evaluated respectively.ResultsThe results showed that (1) the validation accuracies of the LR model were 77.25 and 81.76% in spring and autumn fire prevention periods, respectively. Compared with the LR model, both the mixed LR and GWLR models had significantly improved the fit and validated results, and the GWLR model performed best with an increase of 6.27 and 10.98%, respectively. (2) The three models were ranked as LR model &lt; mixed LR model &lt; GWLR model in predicting forest fire occurrence of Heilongjiang Province. The medium-and high-risk areas of forest fire predicted by the GWLR model were distributed in western and eastern parts of Heilongjiang Province in spring, and western part in autumn, which was consistent with the observed data. (3) Driving factors had strong temporal and spatial heterogeneities; different factors had different effects on forest fire occurrence in different time periods. The relationship between driving factors and forest fire occurrence varied from positive to negative correlations, whether it’s spring or autumn fire prevention period.DiscussionThe GWLR model has advantages in explaining the spatial variation of different factors and can provide more reliable forest fire predictions.
TP53-related signature for predicting prognosis and tumor microenvironment characteristics in bladder cancer: A multi-omics study
Authors: Tao Yuting , Li Xia , Zhang Yushan , He Liangyu , Lu Qinchen , Wang Yaobang , Pan Lixin , Wang Zhenxing , Feng Chao , Xie Yuanliang , Lai Zhiyong , Li Tianyu , Tang Zhong , Wang Qiuyan , Wang Xi 
Published: December 2022

Background: The tumor suppressor gene TP53 is frequently mutated or inactivated in bladder cancer (BLCA), which is implicated in the pathogenesis of tumor. However, the cellular mechanisms of TP53 mutations are complicated, yet well-defined, but their clinical prognostic value in the management of BLCA remains controversial. This study aimed to explore the role of TP53 mutation in regulating the tumor microenvironment (TME), elucidate the effects of TP53 activity on BLCA prognosis and immunotherapy response.Methods: A TP53-related signature based on TP53-induced and TP53-repressed genes was used to construct a TP53 activity-related score and classifier. The abundance of different immune cell types was determined using CIBERSORT to estimate immune cell infiltration. Moreover, the heterogeneity of the tumor immune microenvironment between the high and low TP53 score groups was further evaluated using single-cell mass cytometry (CyTOF) and imaging mass cytometry (IMC). Moreover, pathway enrichment analysis was performed to explore the differential biological functions between tumor epithelial cells with high and low TP53 activity scores. Finally, the receptor–ligand interactions between immune cells and tumor epithelial cells harboring distinct TP53 activity were analyzed by single-cell RNA-sequencing.Results: The TP53 activity-related gene signature differentiated well between TP53 functional retention and inactivation in BLCA. BLCA patients with low TP53 scores had worse survival prognosis, more TP53 mutations, higher grade, and stronger lymph node metastasis than those with high TP53 scores. Additionally, CyTOF and IMC analyses revealed that BLCA patients with low TP53 scores exhibited a potent immunosuppressive TME. Consistently, single-cell sequencing results showed that tumor epithelial cells with low TP53 scores were significantly associated with high cell proliferation and stemness abilities and strongly interacted with immunosuppressive receptor–ligand pairs.Conclusion: BLCA patients with low TP53 scores have a worse prognosis and a more immunosuppressive TME. This TP53 activity-related signature can serve as a potential prognostic signature for predicting the immune response, which may facilitate the development of new strategies for immunotherapy in BLCA.