bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deep learning-based COVID-19 triage tool
Authors: Mahajan Abhishek , Pawar Vivek , Punia Vivek , Vaswani Aakash , Gupta Piyush , S. Bharadwaj K. S. , Salunke Arvind , Palande Sujit D. , Banderkar Kalashree , Apparao M. L. V. 
Published: April 2022

Background:
Easy availability, low cost, and low radiation exposure make chest radiography an ideal modality for coronavirus disease 2019 (COVID-19) detection.

Objectives:
In this study, we propose the use of an artificial intelligence (AI) algorithm to automatically detect abnormalities associated with COVID-19 on chest radiographs. We aimed to evaluate the performance of the algorithm against the interpretation of radiologists to assess its utility as a COVID-19 triage tool.

Materials and Methods:
The study was conducted in collaboration with Kaushalya Medical Trust Foundation Hospital, Thane, Maharashtra, between July and August 2020. We used a collection of public and private datasets to train our AI models. Specificity and sensitivity measures were used to assess the performance of the AI algorithm by comparing AI and radiology predictions using the result of the reverse transcriptase-polymerase chain reaction as reference. We also compared the existing open-source AI algorithms with our method using our private dataset to ascertain the reliability of our algorithm.

Results:
We evaluated 611 scans for semantic and non-semantic features. Our algorithm showed a sensitivity of 77.7% and a specificity of 75.4%. Our AI algorithm performed better than the radiologists who showed a sensitivity of 75.9% and specificity of 75.4%. The open-source model on the same dataset showed a large disparity in performance measures with a specificity of 46.5% and sensitivity of 91.8%, thus confirming the reliability of our approach.

Conclusion:
Our AI algorithm can aid radiologists in confirming the findings of COVID-19 pneumonia on chest radiography and identifying additional abnormalities and can be used as an assistive and complementary first-line COVID-19 triage tool.
Clinicopathologic features and outcomes of diffuse large B-cell lymphoma with extranodal involvement
Authors: Nair Sukesh C. , Gogia Ajay , Arora Shalabh , Kumar Lalit , Sharma Atul , Biswas Ahitagni , Gupta Ritu , Mallick Saumyaranjan 
Published: April 2022

Background:
Extranodal involvement is seen in about 40%–50% of the cases of diffuse large B-cell lymphoma (DLBCL). However, data on the clinicopathological features and outcomes of DLBCL with extranodal involvement, especially in the rituximab era, are scarce from India.

Objectives:
In this study, we aimed to assess the clinicopathological features and outcomes of DLBCL with extranodal involvement among Indian patients.

Materials and Methods:
This retrospective study was conducted on patients with DLBCL, registered in the Department of Medical Oncology of the All India Institute of Medical Sciences, Delhi, India, between January 2014 and December 2018. Patients with nodal DLBCL aged more than 18 years, with concomitant extranodal disease in any anatomical site were included. All patients were treated with multiagent chemotherapy with or without rituximab.

Results:
Median age of the cohort was 50 years (range, 18–86), a male-to-female ratio of 2:1. B-symptoms and bulky disease were seen in 48% and 39% patients, respectively. Bone was the most common site of extranodal involvement observed in 32% patients. Bone marrow involvement was present in 13% patients. Low-risk International Prognostic Index (IPI) was seen in 32% patients and intermediate risk IPI in 38% patients. Cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP)-based treatment was used in 80% of the patients and rituximab (R) was used in 73% of the patients. The objective response rate was 76%, with a complete response rate of 65.5%. After a median follow-up of 26 months, the 3-year progression free survival and overall survival (OS) were 65% and 82.7%, respectively. Involvement of the kidney/adrenal gland and central nervous system, high IPI score, and use of non- R-CHOP regimens were associated with a poor OS on the multivariate analysis.

Conclusions:
The bone is the most common site of extranodal involvement in Indian patients with DLBCL. The outcome of extranodal DLBCL depends on the primary site of disease involvement.
Diagnostic accuracy of mammography in characterizing breast masses using the 5th edition of BI-RADS
Authors: Mohapatra Suvendu Kumar , Das Prafulla Kumar , Nayak Rashmita Binod , Mishra Abhisek , Nayak Bhagyalaxmi 
Published: April 2022

Background:
Breast imaging-reporting and data system (BI-RADS) is intended for standardizing mammography reporting.

Objectives:
We aimed to evaluate the diagnostic precision of the BI-RADS assessment scoring system using histopathological findings as the reference standard. We also aimed to assess the positive predictive value (PPV) of different morphological descriptors for malignancy.

Materials and Methods:
This retrospective record-based analytical study was conducted in the Department of Radiodiagnosis of Acharya Harihar Post Graduate Institute of Cancer, Cuttack, Odisha, a tertiary cancer center in eastern India. We included patients attending the breast cancer unit with various breast complaints who were subjected to mammographic imaging and histopathological examination. The primary outcomes were the sensitivity, PPV, negative predictive value (NPV), and diagnostic accuracy (DA) of the BI-RADS scores for the pathological reports; secondary objective was the evaluation of the mammographic morphological characteristics. Mammography was interpreted using the BI-RADS 5th edition guidelines, without prior knowledge of the biopsy report. A BI-RADS final assessment score between 1 and 5 was assigned, where 1 indicated a normal study, 2 benign, 3 possibly benign requiring follow up, 4 suspicious requiring biopsy, and 5 indicating likely malignant requiring biopsy and further actions.

Results:
Between February 2020 and December 2020, we included 247 patients. All the category 5 lesions were malignant, while 76.5% of category 4 lesions were malignant. PPVs of BI-RADS categories 4a, 4b, and 4c were 38%, 90%, and 94%, respectively. Mammography had a sensitivity, specificity, PPV, NPV, and DA of 98.7%, 47.6%, 87.5%, 90.9%, and 87.9%, respectively. Morphological features that were significantly associated with malignancy were spiculated margins (P = 0.003, PPV = 100%), microlobulated margins (P = 0.005, PPV = 96.5%), irregular shape (P = 0.002, PPV = 89.6%), microcalcification (P = 0.005, PPV = 92.8%), skin thickening (P < 0.0001, PPV = 100%), and architectural distortion (P = 0.003, PPV = 96.7%).

Conclusion:
Digital mammography is a sensitive tool for the evaluation of breast lumps, but BI-RADS final assessment score is subjective as it depends on the interpreter's expertise.
Construction and validation of palliative care nursing theory guidelines for patients with advanced cancer
Authors: Kalyani C. Vasantha , Rohilla Kusum K. , Gupta Amit , Gupta Sweety , Gupta Manoj , Matella Nirmal 
Published: April 2022

Background:
Globally, there are many patients suffering from advanced cancers. There is a limited structured theoretical framework available for providing palliative care to these patients.

Objectives:
We aimed to construct and validate palliative care nursing theory guidelines to provide better palliative services to patients with advanced cancer.

Materials and Methods:
This study was conducted in Departments of Surgery and Radiation Oncology at the All India Institute of Medical Sciences, Rishikesh. In the present study, we used mixed-method design in which both qualitative and quantitative methods were used. In the qualitative study, exploratory surveys were used to derive themes using directed content analysis. We used the prospective cohort methods in the quantitative study. We tested the palliative care nursing theory on 80 patients with advanced gallbladder cancer and their caregivers for 6 months using the European Organization for Research and Treatment of Cancer Quality of Life (EORTC QOL) scale and assessed the survival outcomes.

Results:
Between July 2019 and Dec 2019, we enrolled 25 patients in the qualitative study. Four concepts of palliative care nursing theory were derived, that is, symptomatic management, problem-solving counseling, yoga and meditation, and family or caregiver involvement. Out of these, we developed a conceptual framework and palliative care nursing theory. In the subsequent quantitative study, we then tested this palliative care nursing theory on 80 patients (40 in the interventional group and 40 in the control group) with advanced cancer who were receiving palliative treatment. We provided care according to the palliative care nursing theory guidelines to the patients in the interventional group and found that this resulted in a significant benefit for both overall survival and quality of life (P = 0.0001; 95% confidence interval [CI], 5.97–87.82).

Conclusion:
Our validated palliative care nursing theory is a structured and well-designed tool to provide comprehensive palliative care to patients with cancer. This can guide palliative care teams to provide better palliative care to patients and their families.
La motivación en la contratación pública: análisis de la reciente jurisprudencia europea y española
Authors: RAZQUIN LIZARRAGA MARTÍN MARÍA 
Published: April 2022

El presente trabajo constituye un estudio jurisprudencial sobre
la motivación en la contratación pública. La motivación es un requisito esencial,
cuya falta da lugar a la anulación del acto impugnado, aunque sus efectos suelen
limitarse a la retroacción del procedimiento para que se efectúe una motivación
suficiente. La motivación puede sustentarse en los informes técnicos que fundamentan
la resolución administrativa.
Lan hau kontratazio publikoko motibazioari buruzko azterlan jurisprudentzial
bat da. Motibazioa funtsezko baldintza bat da, eta motibaziorik ezak
aurkaratutako egintza deuseztatzea dakar; hala ere, ondorioak prozeduraren atzeraeraginera
mugatzen dira, behar besteko motibazioa egiteko. Motibazioa administrazio-
ebazpenaren oinarri diren txosten teknikoetan oinarritu daiteke.
This paper constitutes a jurisprudential study on motivación
in public procurement. The statement of reasons is an essential requirement,
whose lack leads to the annulment of the challenged act, although its effects are
usually limited to the retroaction ot the procedure so as to carry out a sufficient
reasoning. The motivation can be based on the technical reports that support the
administrative resolution.
To plant molluscocide production technology
Authors: Danilenko Andrei V , Postevoy Alexey N , Andreyanov Oleg 
Published: April 2022

Currently, the vast range of helminthoses of farm fish and animals is causing significant economic damage. Effective prevention is an important element in the fight against these diseases. An effective method of preventing helminthosis is the destruction by chemical means of shellfish - intermediate helminth hosts. Molluscocidal properties have decoction from leaves, stems and roots of medicinal soap (Saponária officinalis). The article describes the peculiarity of the procedure for preparing a molluscocide agent from this plant by cold alcohol extraction (maceration). The work used dried collection of roots, leaves, stems, flowers and soapwort seeds of medicinal S. officinalis, which was ground in a mortar to form powder (particle sizes 1... 3 mm). The powder was placed in a vessel of fermenter BioFlo to which 96% ethyl alcohol was added (1 g of dried collection per 100 ml of liquid). The speed of the impeller was 150 rpm. Inside the vessel, the temperature was 25 ± 2 ° C. The extraction process was carried out for 24 hours.The proposed technology enables to obtain a substance having high selective toxicity to mollusks. Its use in the form of a 1% solution causes the death of lymnaeids within 24 hours in the treated area. In the future, based on the obtained extract, it is possible to create a prophylactic molluscocide preparation that is inexpensive to manufacture and has low toxicity to humans and animals.
Kihívások és megfelelések a pedagógiai szakszolgálati ellátórendszerben
Authors: Mile Anikó , Kiss László 
Published: April 2022

2013-ban gyökeresen átalakult a pedagógiai szakszolgálati ellátórendszer hazánkban. Az intézményrendszer átszervezésének szakpolitikai céljai között az állami szerepvállalás növelése mellett megjelent az ellátórendszer hatékonyabbá tétele, az egyenlő hozzáférés feltételeinek megteremtése, a területi egyenlőtlenségek kiküszöbölése, valamint a szakszolgálati munka minőségi megújulásához szükséges feltételek biztosítása, az egységes szakmai minőség támogatása.
Az addig különböző fenntartás alatt álló, többféle intézménytípusban, bizonytalan illetékességi körökkel működő szervezetek helyett egységes, tiszta profilú ellátórendszer jött létre megyei/fővárosi szerveződésű intézményekkel. Jelen tanulmány az átalakulás, a szervezeti és szakmai fejlesztés folyamatát mutatja be.
Pengaruh Manajemen Pendidikan Islam Terhadap Kinerja Guru Dalam Mewujudkan Perilaku Keagamaan Siswa (Studi Kasus di SMP Plus Qurrota A’yun Samarang Garut)
Authors: Islam Saepudinil 
Published: April 2022

Tulisan ini bertujuan untuk: untuk mengkaji pengaruh Manajemen Pendidikan Islam terhadap Kinerja Guru dalam mewujudkan Perilaku Keagamaan Siswa. Metodologi penelitian yang digunakan adalah metode penelitian deskriptif dengan teknik survey. Lokasi penelitian adalah di SMP Plus Qurrota A'yun Samarang Garut dengan jumlah responden sebanyak 68 responden. Teknik pengumpulan data menggunakan angket dan dokumentasi. Hasil pengujian hipotesis utama: Terdapat Pengaruh Manajemen Pendidikan Islam terhadap Kinerja Guru dalam Mewujudkan Perilaku Keagamaan Siswa, dengan pengujian analisis jalur. Selanjutnya untuk mengetahui lebih lanjut pengaruh variabel Manajemen Pendidikan Islam (X) berpengaruh terhadap Kinerja Guru (Y) dan Perilaku Keagamaan Siswa (Z) maka dilakukan pengujian, yaitu dengan melihat perbandingan antara thitung dan ttabel. Berdasarkan pengujian diperoleh nilai thitung lebih besar dari nilai ttabel yaitu thitung = 6,7380 > ttabel = 1,998. Dari nilai tersebut diperoleh keputusan H0 ditolak dan H1 diterima, sehingga variabel Manajemen Pendidikan Islam (X) berpengaruh terhadap Kinerja Guru (Y) dan Perilaku Keagamaan Siswa (Z). Signifikansi nilai hasil pengujian di atas didukung pula oleh besaran nilai determinasi (R2YZX) sebesar 0,4112. yang juga menunjukkan besarnya kontribusi Manajemen Pendidikan Islam terhadap Kinerja Guru dalam mewujudkan Perilaku Keagamaan Siswa yaitu sebesar 41,12%, sedangkan sisanya sebesar 0,5888 atau sebesar 58,88% dipengaruhi oleh variabel lain yang tidak dimasukkan ke dalam model.
Book review: Göde Both (2020) Keeping Autonomous Driving Alive. An Ethnography of Visions, Masculinity and Fragility
Authors: Haugland Bård Torvetjønn 
Published: April 2022

The review critiques Göde Both’s book Keeping Autonomous Driving Alive (2020). This book is an ethnographic exploration of a project in which roboticists and computer scientists attempt to make a technologically enhanced Volkswagen Passat drive without a human driver. Through an account grounded in actor-network theory, Both seeks to understand the actual work necessary to make the vehicle drive on its own, as well as the manner in which masculinity and futures are assembled and re-assembled around this emerging technology. The review assesses the merit of Both’s book as a self-contained account of a research project centred on self-driving vehicles, as well as the book’s contribution to the nascent social scientific literature on such vehicles.
تقييم الاداء المؤسسي لوزارة الشباب الاردنية – نظرة تقييمية لمدراء المراكز الشبابية -
Authors: الخزاعله وصفي , اخو ارشيدة فاطمة 
Published: April 2022

هدفت الدراسة إلى تقييم الاداء المؤسسي لوزارة الشباب الاردنية – نظرة تقييمية للمراكز الشبابية، ولتحقيق ذلك استخدم الباحثان المنهج الوصفي، والاستبانة كأداة لجمع البيانات والمعلومات من عينة عشوائية طبيقية قوامها (112) مديراً للمراكز الشبابية في الاردن، وجاءت جميع درجات التقييم بمستوى متوسط وعدم وجود فروق في التقييم تبعا لصفة المركز (شباب، شابات)، بينما أوجدت الدراسة فروقاً إحصائية تبعا لمتغير موقع المركز لصالح القرية عن المدينة، وأوصت الدراسة بضرورة اعتماد بطاقة معايير الأداء المؤسسي لغايات قياس وتقييم أداء مركز وزارة الشباب ومديرياتها.
مدى توافر مهارات تقنيات التعلم عن بعد لدى طلاب جامعة الشرقية في سلطنة عُمان في ضوء بعض المتغيرات
Authors: العجمي قاسم , الصوافية جوخة , السعودي شريف 
Published: April 2022

هدفت هذه الدراسة لقياس مدى توافر مهارات تقنيات التعلم عن بعد لدى طلاب جامعة الشرقية بسلطنة عمان، كما هدفت للكشف عن الفروق بين متوسطات درجات بعض هذه المهارات التقنية تبًعا لمتغيرات (الجنس، الكلية، والسنة الدراسية). حيث تكونت العينة من 256 طالبا وطالبة من طلاب الجامعة المسجلين خلال الفصل الصيفي للعام الدراسي 2019/2020. ولتحقيق أهداف الدراسة قام الباحثون ببناء مقياس تحديد الاحتياج التدريبي في المهارات موضوع الدراسة والتي تكونت من 10 مهارات، وذلك بعد التأكد من صدق المقياس وثبات أداة الدراسة. كما أظهرت الدراسة بأن مهارات تقنيات التعلم عن بعد متوفرة لدى الطلاب عينة الدراسة بدرجة متوسطة، وأظهرت الدراسة عدم وجود فروق ذات دلالة احصائية لمتوسط المهارات بين الذكور والاناث، بينما أظهرت الدراسة فروقا ذات دلالة إحصائية تعزى لمتغير الكلية لصالح طلبة كلية الآداب والعلوم الانسانية، وكذلك أظهرت النتائج وجود فروق إحصائية لمتغير السنة الدراسية لصالح طلبة السنة الثانية. من أهم ما أوصت به الدراسة أن تهتم الجامعات والقائمين على التعليم الجامعي بتوفير برامج تأهيلية في تقنيات التعليم والتعلم المرتبطة بالتعلم عن بعد لطلبة الجامعات.
Fatty liver formation in patients with breast cancer on tamoxifen therapy in Iraqi female
Authors: Saeed Israa Jarjees Rasheed , Jassim Oday Abdulhadi , Mahdi Marwah Adel 
Published: April 2022

This is a prospective, hospital based, case-control study conducted at Oncology and Nuclear medicine specialist Hospital, in Nineveh province in Iraq during the period from February 2018 to November 2018, to determine the prevalence of fatty liver formation in tamoxifen treatments by ultrasonographic examinations. Fifty- patients receiving tamoxifen were involved in this study, 11 of these were premenopausal from the premenopausal subgroup patients14 (28%) their age (25-44) years in which 10 of them were Grade I fatty liver & 1 case was Grade II fatty liver , no cases seen had Grade III , and 32 patients were postmenopausal were from post menopausal subgroup patients 36 (72%) range their age (45-78) years, in which 16 of them had fatty liver Grade I, & 16 of them had fatty liver Grade II , no cases seen had Grade III, The duration of tamoxifen was range (>6–72) months, with 33control case, which were 24 case premenopause and 9 case postmenopause which had 3 of them were grade II in premenopausal age group , while 3 cases were postmenopausal patients age group in which 1 case was Grade I fatty liver & 2 cases were Grade II.
The influence of fixed orthodontic retainer on oral microbiota
Authors: Al-Ali Dhuha A. , Groosh D. Al 
Published: April 2022

Background: The oral cavity is a wide versatile microbial community in which many microbial species coexist in harmony. However, with certain circumstances, i.e. orthodontic appliances, pathogenic biofilm outgrowth occurs. The aim: The aim of this study was to compare opportunistic pathogens, associated with dental caries and periodontal disease in addition to Candida albicans, between healthy individuals and patient wearing fixed orthodontic retainers. Method: Fourty eight subjects were recruited andwere divided into retainer wearers and control cohort groups. Biofilm samples from the lingual surface of the mandibular anterior teeth of the control group and the fixed retainer surface were evaluated to detect Streptococcus mutans, Lactobacillus acidophilus, Aggrigatibacter actinomycetemcomitans, Fusobacterium nucleatum and C. albicans. Additionally, plaque (PI) and gingival (GI) indices were measured at the mandibular anterior teeth in both groups. The results: The results showed a significant increase in total micobial count in retainer group (p<0.001). The prevalence of microbial cultivity was higher in retainer group with a significant increase in PI and GI. Moreover, there was a high correlation between these genera and the GI. The conclusion: fixed retainer may increase cariogenic and periodontal pathogens and compromise oral health.
Driving pressure versus right ventricular echocardiography parameters as a predictive for acute respiratory distress syndrome outcome
Authors: Sayed Mohammed Mahmoud , Elatroush Hatem , Nassar Yasser , Samir Nael , Elghoneme Mohamed Omar 
Published: April 2022

Background: Acute respiratory distress syndrome (ARDS) is an inflammatory disease that affects the lung in a heterogeneous manner , so that ,even ideal body weight (IBW) based tidal volume may apply different lung stress and strain according to the available aerated lung areas. Airway driving pressure (DP) is the difference between airway plateau pressure (P plat) and positive endexpiratory pressure (PEEP), it can be used as a bedside surrogate for lung stress in several previous studies. Acute corpulmonale manifested by pulmonary hypertension and right ventricular dysfunction occurs as a consequence for ARDS with a prevalence ( 25% to 61%) in different studies. Objectives : This study was designed to show he clinical value of airway driving pressure and right heart echocardiography parameters in predicting ARDS outcome , and to correlate between airway pressures and right ventricle parameters. Methodology : fifty ARDS patients were diagnosed by Berlin criteria and monitored for airway pressures including DP and Pplat on day 0, day 3 and day 7. transthoracic echocardiography was used to assess RV parameters on day 0 and day 7 . According the ICU mortality patients are divided into survivors and nonsurvivors.
Lumbopelvic stabilization versus Pilates exercises on spatiotemporal gait parameters in chronic nonspecific low back pain
Authors: Elfeky Heba M , Elhafez Haytham M , Genedy Ahmed F , Elfahl Ahmed M , El-Azeim Alshaymaa S Abd 
Published: April 2022

Aim of the work: The purpose of the current study is to trace and investigate how lumbopelvic stabilization and Pilates exercises affect the spatiotemporal aspects of gait in persistent nonspecific low back pain cases (NS-CLBP). Methods: Patients with NS-CLBP (N=90) were randomly assigned to one of three groups: group A (stabilization + traditional therapy), group B (Pilates plus traditional therapy), and group C (conventional therapy) in a single-blinded randomized clinical trial with 12 treatments over six weeks. A Walkway pressure measurement system was used to determine both spatial and temporal parameters. The Visual Analog Scale, Modified Oswestry Disability Questionnaire, Biering–Sorensen test, and trunk flexion endurance test were adopted successfully to assess pain, function, and isometric endurance of trunk extensor and flexor. Results: According to a cross-group analysis, a statistically significant effect was found when p = 0.001 and f-value = 3.12. Also, a statistically clear interaction was figured out between treatment and time when p = 0.0001 and f-value = 3.44. Following therapy, the Pilates group showed a decrease in temporal parameters, pain, and functional impairment, as well as an increase in cadence and velocity (p 0.05).