bluuebunny/crossref_metadata_2025_split huggingface dataset:
gcCov: Linked open data for global coronavirus studies
Authors: Shi Wenyu , Fan Guomei , Shen Zhihong , Hu Chuan , Ma Juncai , Zhou Yuanchun , Meng Zhen , Hu Songnian , Bi Yuhai , Wang Liang , Yu Haiying , Lin Siru , Sun Xiuqiang , Zhang Xinjiao , Liu Dongmei , Sun Qinlan , Wu Linhuan 
Published: March 2022

Impact statementWe present a method of mapping data from publicly available genomics and publication resources to the Resource Description Framework (RDF) and implement a server to publish linked open data (LOD). As one of the largest and most comprehensive semantic databases about coronaviruses, the resulted gcCov database demonstrates the capability of using data in the LOD framework to promote correlations between genotypes and phenotypes. These correlations will be helpful for future research on fundamental viral mechanisms and drug and vaccine designs. These LOD with 62,168,127 semantic triplets and their visualizations are freely accessible through gcCov at https://nmdc.cn/gccov/.
Higher strength carbon fiber lithium‐ion polymer battery embedded multifunctional composites for structural applications
Authors: Biswas Pias Kumar , Liyanage Asel Ananda Habarakada , Jadhav Mayur , Agarwal Mangilal , Dalir Hamid 
Published: March 2022

AbstractThis study proposes and evaluates the structural integrity of a carbon fiber reinforced polymer (CFRP) composite containing encapsulated lithium‐ion polymer (Li‐Po) batteries. A comparison of various composite structures made of CFRP having the core of lithium‐ion batteries is conducted. Electrospinning is globally recognized as a flexible and cost‐effective method for generating continuous nanofilaments. In this study, epoxy‐multiwalled carbon nanotubes (CNT/epoxy) were electrospun onto CFRP layers, which improved interfacial bonding and strong adhesion between the layers which ultimately worked as an effective packaging for Li‐ion batteries. This composite structure showed enhanced mechanical strength compared to the standard CFRP laminate structure due to incorporating electrospun CNT/epoxy nanofibers in between the layers. An alternate method was proposed for comparison where CNT/epoxy was air sprayed onto the CFRP layers. CFRP structure containing airsprayed CNT/epoxy was found to be stronger than standard CFRP laminate structure, although not as strong as electrospun CNT/epoxy enhanced CFRP laminates. Finally, the design validation, manufacturing method, and electromechanical characterization of multifunctional energy storage composites (MESCs) were examined and compared. Electrochemical characterization showed that MESCs with electrospun CNT/epoxy nanofibers enhanced CFRP laminate under loading conditions had similar performance to the standard lithium‐ion pouch cells without any loading. The mechanical robustness of the proposed CFRP composite structures enables their manufacturing as multifunctional energy‐storage devices for electric vehicles and other structural applications.
Two‐Color Passively Q‐Switched Raman Microchip Laser with Tunable Power Intensity Ratio and Elliptical Polarization
Authors: Yang Haolin , An Yinming , Chen Dimeng , Dong Jun 
Published: March 2022

AbstractElliptically polarized high peak power two‐color lasers have potential applications on material science, biology, optical detection, and terahertz wave generation. Two‐color pulsed lasers with flexible power intensity ratio are essential for analyzing material properties, however, control of power ratio between two lasers is a challenge for developing compact passively Q‐switched (PQS) solid‐state laser. Here, taking advantage of Nd:YAG/Cr4+:YAG composite crystal and a‐cut YVO4 crystal, a PQS Raman microchip laser is developed for generating a two‐color Raman laser with tunable power intensity ratio between two Raman lasers and elliptical polarization. Power intensity ratio tuned from 1 to 0 between 1166 nm Raman laser and 1166/1176 nm two‐color laser is achieved by adjusting a‐cut YVO4 crystalline orientation. State of polarization of Raman laser is elliptical polarization. The ellipticity is flexibly tuned from 0.3 to 0.91 by adjusting pump power and a‐cut YVO4 crystalline orientation. The Raman laser pulses with peak power of 6.4 kW and pulse width of 1.5 ns are obtained. The synchronized Raman laser pulse repetition rate is 14.3 kHz. This work enables development of a compact high peak power two‐color Raman laser with flexible control of power intensity ratio between two color lasers in a diode pumped PQS Raman microchip laser.
Vaporization and thermodynamic properties of the SrO‐Al2O3 system studied by Knudsen effusion mass spectrometry
Authors: Lopatin Sergey I. , Shugurov Sergey M. , Tyurnina Natalia G. , Tyurnina Zoya G. , Polyakova Irina G. , Balabanova Ekaterina A. 
Published: March 2022

RationaleStrontium aluminates can be used as refractory construction materials at temperatures up to 2000°С or as the materials for immobilization of long‐lived radioactive waste. The SrО‐Al2O3 system is one of the more complicated oxide systems used for the creation of new radio‐transparent materials. The exploitation of such materials at high temperatures demands the knowledge of the thermal stability of the compounds and solid solutions formed in the SrО‐Al2O3 system.MethodsThe synthesis of the samples in the SrO‐Al2O3 system was carried out by a ceramic method at 1250°C. The characterization of the samples was accomplished with the use of X‐ray diffraction (XRD). The vaporization of the samples under study was performed from a twin tungsten effusion cell using the Knudsen effusion mass spectrometry method.ResultsThe temperature dependences of partial pressures of vapor species over 4SrO·Al2O3, 3SrO·Al2O3, SrO·Al2O3, SrO·2Al2O3 and SrO·6Al2O3 in a wide range of temperatures were determined. The component activities, the Gibbs energies of mixing and the standard enthalpies of individual strontium aluminates were obtained.ConclusionsThe thermodynamic properties of the SrO‐Al2O3 system at high temperatures are characterized by negative deviation from ideality. The vaporization processes and thermodynamic properties of the SrO‐Al2O3 system were obtained for the first time.
Conceptual frameworks in indicator‐based assessments of urban sustainability—An analysis based on 67 initiatives
Authors: Halla Pekka , Merino‐Saum Albert 
Published: March 2022

AbstractUrban sustainability is today commonly considered to be a crucial determinant of global sustainable development, and indicator‐based assessments represent a popular means of operationalizing this complex concept. An important aspect of these assessments concerns the elaboration of accompanying conceptual frameworks. Despite the pivotal role of such frameworks, they are often developed in an unstructured manner, without consideration of their potential purposes and impacts, and without awareness and evaluation of available options. Here, we discuss this topic based on both theoretical considerations and the analysis of the conceptual frameworks of 67 urban sustainability indicator initiatives. The discussion makes two contributions: First, we provide guidance for assessment developers for leveraging the potential of conceptual frameworks. Second, considering the analyzed frameworks as de facto definitions of urban sustainability allows us to advance understanding of the meaning of this complex concept, and to critically discuss the conceptual shortcomings that remain in current assessment practice.
Quantiles based personalized treatment selection for multivariate outcomes and multiple treatments
Authors: Kulasekera Karunarathna B. , Siriwardhana Chathura 
Published: March 2022

AbstractIn this work, we propose a method for individualized treatment selection when there are correlated multiple responses for the treatment () scenario. Here we use ranks of quantiles of outcome variables for each treatment conditional on patient‐specific scores constructed from collected covariate measurements. Our method covers any number of treatments and outcome variables using any number of quantiles and it can be applied for a broad set of models. We propose a rank aggregation technique for combining several lists of ranks where both these lists and elements within each list can be correlated. The method has the flexibility to incorporate patient and clinician preferences into the optimal treatment decision on an individual case basis. A simulation study demonstrates the performance of the proposed method in finite samples. We also present illustrations using two different datasets from diabetes and HIV‐1 clinical trials to show the applicability of the proposed procedure for real data.
A Case of Methotrexate-Associated Epstein-Barr Virus-Positive Mucocutaneous Ulcer
Authors: Sakamoto Keiko , Baba Takeshi , Takatori Hiroaki , Nagao Keisuke , Misawa Junko , Honda Tetsuya 
Published: March 2022

Abstract
Epstein-Barr virus-positive mucocutaneous ulcer (EBVMCU) is a B-cell proliferative disorder that has been designated as a provisional entity in the 2017 World Health Organization classification for lymphoid neoplasms. While EBVMCU may contain varying numbers of cells with Hodgkin and Reed-Sternberg cells-like morphology, the clinical course is benign and must be distinguished from lymphomas. Patients who develop EBVMCU are commonly immunocompromised, with methotrexate (MTX) as the leading cause. Most previously reported cases of EBVMCU describe mucosal ulcers with very little documentation on skin lesions and its course. Here, we report a case of MTX-associated EBVMCU of the lower leg that underwent spontaneous regression after MTX withdrawal, during which negative conversion of local Epstein-Barr virus activation was confirmed.
Understanding the Experiences of Anger in the Onset and Progression of Psoriasis: A Thematic Analysis
Authors: Hughes Olivia , Hunter Rachael 
Published: March 2022

Abstract
Psoriasis is a chronic inflammatory skin condition, which can be affected by stress. Living with psoriasis can trigger negative emotions, which may influence quality of life. The present study explored the lived experiences of people with psoriasis with attention to the potential role of anger in the onset and progression of the chronic skin condition. Semi-structured qualitative interviews were conducted with 12 participants (n = 5 females, n = 7 males) recruited from an advert on a patient charity social media platform. Data were transcribed and analysed using thematic analysis. Four key themes were identified: (1) anger at the self and others, (2) the impact of anger on psoriasis: angry skin, (3) shared experiences of distress and (4) moving past anger to affirmation. Findings suggest that anger can have a perceived impact on psoriasis through contributing to sensory symptoms and unhelpful coping cycles, and points to a need for enhanced treatment with more psychological support. The findings also highlight the continued stigma which exists for those living with visible skin conditions and how this may sustain anger for those individuals. Future research could usefully focus on developing targeted psychosocial interventions to promote healthy emotional coping.
Synthesis of Quinolines by the Skraup Reaction: Hierarchical Zeolites vs Microporous Zeolites
Authors: Grigorieva Nellya G. , Bayburtli Alsu V. , Travkina Olga S. , Bubennov Sergey V. , Kuvatova Rezeda Z. , Artem'eva Anna S. , Kutepov Boris I. 
Published: March 2022

AbstractThe activity, selectivity, and stability of microporous highly dispersed zeolites (H‐Y, H‐ZSM‐5) and granulated hierarchical zeolites (H‐Yh and H‐ZSM‐5h) were studied in the synthesis of quinolines by the Skraup reaction. Texture, porous structure, morphology of crystals, acidic properties were characterized by XRD, XRF, N2 adsorption‐desorption, SEM, NH3‐TPD methods. It was found that quinoline, 2‐ and 4‐methylquinolines are the main products in the reaction of aniline with glycerol in the presence of the studied catalysts. H‐ZSM‐5h and H‐Yh catalysts are more efficient than catalysts H‐ZSM‐5 and HY and provide a yield of quinolines to 72.4 (H‐ZSM‐5h) and 60.2 % (H‐Yh) at 450 °C, 0.2 h−1, the molar ratio of aniline:glycerol=1 : 3. The high activity and selectivity of hierarchical zeolites are due to the presence of meso‐ and macropores, as well as nanocrystals of 15–100 nm size. It was reported that hierarchical catalysts exhibit higher stability in the reaction compared with microporous zeolites.
Highly Efficient Multi‐Tasking Porphyrin‐Based Chemosensor for Mercury Ions
Authors: Singha Jyotirlata , Patra Diptendu , Kumar Pawan , Shunmugam Raja 
Published: March 2022

AbstractPorphyrin‐based monomeric and polymeric sensors are emerging as a desirable alternative to efficient sensors due to their unique optical properties and biocompatibility. An efficient new sensor Acpmono and Acppoly were designed and synthesized for selective and efficient mercury detection at ppm‐level. UV‐visible and fluorescence spectroscopic techniques were studied for the sensing performance of both the monomeric and the polymeric sensors. Mechanism of interaction between sensors was confirmed by proton nuclear magnetic resonance (NMR) titration, Ultraviolet‐visible and fluorescence spectroscopic titration, mass spectrometry, time‐correlated single‐photon count (TCSPC) study. Furthermore, a “turn‐off” mode has been established to detect noble heavy metal mercury (Hg2+) by quenching the red fluorescence of sensor molecules. The real‐time application of Acpmono and Acppoly were studied by preparing paper strips and detecting Hg2+ from beauty products in a facile way. Cell viability was evaluated for sensors Acpmono and Acppoly to living HeLa cells using the MTT assay technique to investigate the applicability of the sensors in a biological medium. Based on the MTT assay data of both monomeric and polymeric sensors, the cell imaging of endogenous Hg2+ ions was explored in living HeLa cells.
Preparation of Nitrogen‐Doped Carbon Materials Based on Chitosan for Acetylene Hydrochlorination
Authors: Xu Dong , Lu YuSheng , Liu Li , Lu FangJie , Zhu Mingyuan 
Published: March 2022

AbstractIn this study, we used a simple strategy of directly calcinating chitosan to prepare nitrogen‐doped carbon catalysts for acetylene hydrochlorination. The total content of nitrogen in Chi800 catalyst is 5.88 %, including pyridinic nitrogen, pyrrolic nitrogen, and graphitic nitrogen. The acetylene conversion of Chi800 at 220 °C can reach 91 % due to the existence of the pyridinic nitrogen and pyrrolic nitrogen active sites. In order to improve the stability of catalysts prepared from chitosan, ZnCl2 is used to expand pores of chitosan to prepare Chi800‐E. The specific surface area of the catalyst Chi800‐E with expanded pores can reach 1299.08 m2 g−1. The Chi800‐E shows the acetylene conversion of 94 % and good stability up to 60 hours in a test at 220 °C.
Coumarin‐Chalcones Generated from 3‐Acetylcoumarin as a Promising Agent: Synthesis and Pharmacological Properties
Authors: Nasab Narges Hosseini , Azimian Fereshteh , Kruger Hendrik G. , Kim Song Ja 
Published: March 2022

AbstractDeveloping novel chemical entitiesviadifferent reactions and mechanisms is one of the hottest topics in drug development. The coumarin moiety displays good cell permeability and has numerous medicinal and pharmaceutical applications. It is utilized in the preparation of a wide range of molecules. Herein, we have focused on the application of 3‐acetylcoumarin as a starting material for the systematic synthesis of various types of heterocyclic compositions including coumarin‐chalcone compounds, which exhibit a broad variety of bioactivities, including antituberculosis; enzyme‐inhibition; antioxidant; anti‐inflammatory etc. After introducing the synthesis of 3‐acetylcoumarin, the review proceeds with a comprehensive presentation of the synthesis of coumarin‐chalcones under various conditions. Last, the reactions of prepared coumarin‐chalcones through different mechanisms and the outcomes achieved through such reactions are discussed. It is envisaged that this review will prompt researchers to expand on the knowledge gained in this field the last twenty years.
Near‐infrared chemiluminescent carbon nanogels for oncology imaging and therapy
Authors: Shen Chenglong , Jiang Tianci , Lou Qing , Zhao Wenbo , Lv Chaofan , Zheng Guangsong , Liu Hangrui , Li Pengfei , Dai Lingling , Liu Kaikai , Zang Jinhao , Wang Feng , Dong Lin , Qu Songnan , Cheng Zhe , Shan Chongxin 
Published: March 2022

AbstractCarbon nanogels (CNGs) with dual ability of reactive oxygen species (ROS) imaging and photodynamic therapy have been designed with self‐assembled chemiluminescent carbonized polymer dots (CPDs). With efficient deep‐red/near‐infrared chemiluminescence (CL) emission and distinctive photodynamic capacity, the H2O2‐driven chemiluminescent CNGs are further designed by assembling the polymeric conjugate and CL donors, enabling an in vitro and in vivo ROS bioimaging capability in animal inflammation models and a high‐performance therapy for xenograft tumors. Mechanistically, ROS generated in inflammatory sites or tumor microenvironment can trigger the chemically initiated electron exchange luminescence in the chemical reaction of peroxalate and H2O2, enabling in vivo CL imaging. Meanwhile, part of the excited‐state electrons will transfer to the ambient H2O or dissolved oxygen and in turn lead to the type I and type II photochemical ROS production of hydroxyl radicals or singlet oxygen, endowing the apoptosis of tumor cells and thus enabling cancer therapy. These results open up a new avenue for the design of multifunctional nanomaterials for bioimaging and antienoplastic agents.
Determination of compressive strength of lightweight aggregate concrete in service using gene expression programming based on semi‐direct ultrasonic pulse velocity testing
Authors: Jafari Saeed , Hadianfard Mohammad Ali , Mahini Seyed Saeed 
Published: March 2022

AbstractStructural lightweight aggregate concrete (SLWAC) can increase the ability of buildings to resist earthquakes by significantly reducing the overall weight of structures. Determining a relationship for assessing the concrete compressive strength of these structures using non‐destructive methods can save both time and money. This study aims to estimate the compressive strength of SLWAC using a model of gene expression programming (GEP) and semi‐direct ultrasonic pulse velocity. A hundred specimens of lightweight concrete were made using clay and natural (mineral) pumice aggregates with the maximum nominal sizes of 12.7 mm (½ inch) and 19.2 mm (¾ inch), respectively. Semi‐direct ultrasonic testing of the specimens was then undertaken in the laboratory. The results show a high correlation coefficient for the equations derived from the GEP. Moreover, the equations obtained from GEP for three types of SLWAC, based on semi‐direct ultrasonic pulse velocity, are compatible with equations obtained from the direct ultrasonic velocity method. The simplicity of generated equations increases the practicality and convenience in the working environment and actual conditions. The R2(goodness of fit) values of proposed equations for LWA01, LWA02, and LWA03 specimens were 0.912, 0.962, and 0.985, respectively. It was concluded that based on the semi‐direct ultrasonic pulse velocity and derived formulas, the compressive strength of SLWAC can be confidently predicted using GEP.
A multi‐metric movement model for identifying elk parturition events
Authors: Mohr Adam S. , Ewanyk Jon , Hardy Owen , Windsor Justin , Zulliger Erin , Hilson Carrington , Gunther Micaela Szykman , Bean William T. 
Published: March 2022

AbstractFor wildlife managers, identifying the time and location of ungulate parturition events is necessary to protect parturition habitat and inform population models. Current methods for identifying parturition events include neonatal capture and monitoring and visual analysis of location data, which are resource intensive and subject to biases. Recently, movement‐based analyses using the spatial and temporal patterns contained in location data have shown promise for identifying parturition behavior; however, questions regarding efficacy and best practice have limited the adoption of such movement‐based parturition models into management programs. We used location data collected between 2017−2018 from a California population of female Roosevelt elk with known parturition status to build a set of movement‐based models. We compared each model's ability to accurately classify individual's parturition status and identify the timing of parturition. The top model showed that within 72 hours of a parturition event, elk made smaller movements, had smaller home ranges, and had longer visits to individual locations. Of the 16 individuals in our study with known parturition status, our approach to classifying an individual's status was 81% accurate in cross‐validation, which increased to 100% accuracy when the complete dataset was used to train the top model. We then used the top, global and single‐metric models to establish probability thresholds and identify parturition events for collared‐elk with unknown parturition status. Our results align with a growing number of studies that have shown movement‐based parturition models are a reliable method that could augment or replace field‐based techniques for identifying parturition events and quantifying parturition rates in ungulate populations.
Nonagermanide Zintl Clusters with Mg2+ Counter Ions
Authors: Wallach Christoph , Klein Wilhelm , Fässler Thomas F. 
Published: March 2022

AbstractIon exchange processes are rarely investigated with respect to tetrel element Zintl clusters. We now discovered that the addition of Mg complexes to nonagermanide anions comprising K+ counter cations results in an exchange of the alkali ions by alkaline earth cations. Upon stirring K[Ge9{Si(TMS)3}3] (TMS=trimethylsilyl) and Mg(NacNacMes)I (NacNacMes=N,N’‐bis(2,4,6‐trimethylphenyl)‐β‐diketiminate) in MeCN the product [Mg(NacNacMes)(MeCN)4][Ge9{Si(TMS)3}3]⋅ MeCN is formed. Reactions of Mg(NacNacMes)I with K4Ge9 in liquid ammonia as a solvent yielded [K[2.2.2]crypt]4[Mg(NacNacMes)(NH3)4]2[Ge9−Ge9] ⋅ 32.58 NH3 featuring a mixed alkali/alkaline earth metal cationic sphere and an oxidative coupling of the [Ge9]4− clusters. From comparable reactions of [Mg(NacNacMes)]2 with K4Ge9 or K12Ge17 in liquid ammonia crystals of [K[2.2.2]crypt][NacNacMes] ⋅ NH3 and [K(18‐crown‐6)][NacNacMes] ⋅ 3 NH3, respectively, were isolated. All compounds were characterized by means of single crystal structure determination.
Social introductions of multiple groups of dwarf mongooses (Helogaleparvula)
Authors: Richmond Stephanie , Mattingly Victoria , Carmean Mallory , Fieseler Carol , Pilgram‐Kloppe Katie 
Published: March 2022

AbstractProtocols for managing dwarf mongooses (Helogaleparvula) in zoological institutions do not currently account for the introduction of separate social groups. The Association of Zoo and Aquarium Dwarf Mongoose Species Survival Program©and Saint Louis Zoo collaborated in the first documented introduction of multiple individuals spanning three separate social groups. Taking into consideration the social structure of this species, we developed a modified process for performing such an introduction. Neutral territories, olfactory introductions, visual introductions with limited physical contact (“howdy”), and keeper–animal relationship‐building proved to be strong components leading to successful introductions. The result was a cohesive social group of four male and six female dwarf mongooses. This successful introduction is described and presented to provide a foundation for other institutions seeking to conduct similar introductions in the future.