bluuebunny/crossref_metadata_2025_split huggingface dataset:
Moral Universals: A machine-reading analysis of 256 societies
Authors: Alfano Mark , Cheong Marc , Curry Oliver 
Published: July 2022

Abstract
What is the cross-cultural prevalence of the seven moral values posited by the theory of “Morality-as-Cooperation”? Previous research, using hand-coding of ethnographic accounts of ethics from 60 societies, found examples of most of the seven morals in most societies, and observed these morals with equal frequency across cultural regions. Here we extend this analysis, by developing a new Morality-as-Cooperation Dictionary (MAC-D), and using Linguistic Inquiry and Word Count (LIWC) to machine-code ethnographic accounts of ethics from an additional 196 societies (the entire HRAF corpus). Again, we find evidence of most of the seven morals in most societies, across all cultural regions. The new method allows us to detect minor variations in morals across region and subsistence strategy. And we successfully validate the machine-coding against the previous hand-coding. These findings lend further support to the theory of ‘morality-as-cooperation’. And MAC-D emerges as the most comprehensive and well-validated tool for machine-reading moral corpora. We discuss the limitations of the current study, as well as prospects for future research.
Paternal methotrexate exposure affects sperm small RNA content and causes craniofacial defects in the offspring
Authors: Jimenez Nagif Alata , Castellano Mauricio , Santillan Emilio , Boulias Konstantinos , Boan Agustin , Padilla Luisa Arias , Fernandino Juan , Greer Eric , Tosar Juan , Cochella Luisa , strobl-mazzulla Pablo 
Published: July 2022

Abstract
Folate is an essential vitamin for vertebrate embryo development. Methotrexate (MTX) is a folate antagonist that is widely prescribed for autoimmune diseases, blood and solid organ malignancies, and dermatologic diseases. Although it is highly contraindicated for pregnant women, because it is associated with an increased risk of multiple birth defects, the effect of paternal MTX exposure on their offspring has been largely unexplored. Here, we found MTX treatment of adult medaka male fish (Oryzias latipes) causes cranial cartilage defects in their offspring. Small non-coding RNA (sncRNAs) sequencing in the sperm of MTX treated males identify differential expression of a subset of tRNAs, with higher abundance for specific 5’ tRNA halves. Sperm RNA methylation analysis on MTX treated males shows that m5C is the most abundant and differential modification found in RNAs ranging in size from 50 to 90 nucleotides, predominantly tRNAs, and that it correlates with greater testicular Dnmt2 methyltransferase expression. Overall, our data suggest that paternal MTX exposure alters sperm sncRNAs expression and modifications that may contribute to developmental defects in their offspring.
Management of Penile Post-circumcision Ischemia by Pentoxifylline Infusion and Hyperbaric Oxygen Therapy
Authors: Fahmy Mohamed A. Baky , Sabra Tarek Abdelazeem , Abdelmohsen Sarah Magdy , Gad Dalia 
Published: July 2022

Abstract
Background: Post-circumcision penile ischemia is a devastating complication. We will present our experience in managing children with various forms of penile ischemia.Material and methods: This cohort prospective observational study was performed on all male children with post-circumcision penile ischemia between April 2017 and October 2021. A designed and approved protocol includes a combination of early pentoxifylline infusion, hyperbaric oxygen inhalation, early catheterization, and appropriate surgical debridement were applied for all cases. Data of patient age, anesthesia method, monopolar diathermy use, early presentation and positive wound culture were collected and analyzed statistically.Results: During the study period a 3,382 child were circumcised for non-medical reason; 23 children were diagnosed with penile ischemia (0.7%), among other complications (9%) Most of the penile ischemia is associated with use of monopolar diathermy (74%), compressive wound dressing to control post-circumcision bleeding and infections are responsible for ischemia in 52.2% and 43.5% of cases. Inexperienced physicians were commonly responsible for ischemia (73.9%). Patients managed at first 24 hours had better outcomes than those who were presented later (p = 0.001).Conclusion: In children with post-circumcision penile ischemia, a combination of hyperbaric oxygen therapy and pentoxifylline is effective, and reduces penile tissue loss.
Characteristics and Outcome of Mechanically ventilated Children aged 1month-18rs at the University of Gondar Hospital Pediatric Intensive Care Unit ,Northwest Ethiopia,from June 1,2015 to September 30,2021
Authors: Kokeb Mehretie , Biazen Mulualem 
Published: July 2022

Abstract
Background: It is mandatory for the clinicians to understand the events occurring in the Pediatric Intensive Care Unit (PICU) and outcome of mechanically ventilated children for improving the quality of care of the critically ill child. There are many factors which are associated with increased magnitude of mortality in ventilated children. Therefore this study will assess the overall characteristics and outcome of mechanically ventilated children aged 1month-18years at the University of Gondar Hospital, Pediatric Intensive Care Unit.Methods: Institution based retrospective cross-sectional study was conducted on 115 children admitted and mechanically ventilated at PICU of the University of Gondar Hospital from June2015 to September 2021.Data were collected by a structured data extraction tool from the medical records. Data analysis was done by using SPSS version 20. Both descriptive and analytical statistical procedures were utilized. To identify associated factors with the outcome, both bivariate and multi-variate logistic regression analysis were applied. The results of the regression analysis were reported as OR with their 95% confidence interval and significance of p-value below 0.2 and 0.05 in Bivariate and multi variate logistic regressions, respectively..Result: The overall mortality was reported to be 54.8% and clinical characteristics of ventilated children showed that neurologic emergencies (coma)41(35.7%) and Mmalignancies which found in 20(17.4%) were the major reasons for mechanical ventilation. Frequently used mode was SIMV (79.1%) and CPAP was the preferred method of weaning (50%).Conclusion and recommendation: The mortality rate of mechanically ventilated pediatric patients at the University of Gondar Hospital ,PICU was 54.8%. The main cause of death was Acute Respiratory Distress syndrome. SIMV was the main mode and ETT was the only way to access the airway. Severe Acute Malnutrition ,extubation during night and duration of PICU stay were significant predictors of PICU mortality.
Cerebral Fat Embolism Syndrome Case Series
Authors: thangavel saraswathi 
Published: July 2022

Abstract
Fat embolism is the presence of fat particles within the microcirculation, while FES is the systemic manifestation of fat emboli within the microcirculation. FES commonly presents with ards, altered mental status, and dermatological manifestations which occur commonly after traumatic long-bone fractures, though the incidence reported by varies studies range from 1–33%. Here we discuss the two young patients presented with cerebral fat embolism syndrome. Cerebral FES may manifest from minimal changes in mentation to deep coma. Early suspicion in patients with no traumatic neuro parenchymal injury and MRI of brain will be helpful for the early diagnosis
The Clinical Outcomes of Stereotactic Body Radiotherapy for Liver Metastasis and Hepatocellular Carcinoma: a retrospective study
Authors: Liu Canyu , Yi Qing , Han Xu , Zhou Xuerong , tan cheng , Jiang Rui 
Published: July 2022

Abstract
Purpose
This retrospective clinical study expounded the clinical application details of stereotactic radiotherapy for liver cancer established in our center.
Method
The therapeutic effect and prognosis of liver cancer patients treated with stereotactic body radiation therapy (SBRT) from 2011 to 2019 were analyzed retrospectively. The clinical and radiotherapy data were collected and analyzed. Overall survival (OS), local control (LC) rates and progression-free survival (PFS) were evaluated using Kaplan Meier analysis and log-rank test. Local progression was defined as irradiated tumor growth in dynamic computed tomography follow-up. Treatment-related toxicities were assessed according to the Common Terminology Criteria for Adverse Events version 4.3.
Results
Thirty-six patients with liver cancer were enrolled in this study. The median follow-up time was 21.4 months. The median OS time was 20.4 (95% confidence interval [CI]:6.6–34.2) months, and the 1- and 2-OS rates were 59.6 and 44.2%, respectively. The median PFS time was 17.3 (95% CI:11.8–22.8) months, and the 1- and 2-year PFS rates were 65.6% and 39.1%, respectively. The 1- and 2-year local control rates were 94.2% and 83.4%, respectively. The most common grade IV toxicity was AST/ALT elevation (5.6%) followed by thrombocytopenia (2.8%). There were no cases of grade III/IV radiation pneumonia and digest discomfort.
Conclusion
The SBRT technology applied in our center for liver cancer is safe and effective. The prescribed dosage (14Gy × 3 Fractions/16Gy × 3 Fractions) we used was reliable and efficient.
Effects of Recreational Dance on the Attention Span and Quality of Life of Individuals With Autism Spectrum Disorders
Authors: AIYEJUSUNLE COZENS BANKOLE , OLAWALE OLAJIDE AYINLA , OSHODI YEWANDE OLUFUNMILAYO , AJAKAIYE DEBORAH ERIOLUWA 
Published: July 2022

Abstract
Background/ objectives The aim of this study was to determine the effects of recreational dance on the attention span (AS) and quality of life (QoL) of individuals with autism spectrum disorders (ASDs). Methods Eighteen participants were recruited for this study. Both control and intervention groups participated in ball catching/throwing together for 30 minutes, with extra 30minutes sessions of recreational dance in the intervention group. Both attention span and QoL were measured using the manual stopwatch and the Quality of Life In Autism (QoLA) questionnaire, respectively before and after each treatment session. Results AS improved significantly in both groups but the intervention group had greater improvement (from p= 0.036 to p=0.004). Conclusion Recreational dance is beneficial for individuals with ASDs.
Advanced Fashion Recommendation System for Different Body Types using Deep Learning Models
Authors: Wazarkar Seema , Patil Shruti , Gupta Pratik S. , Singh Kriti , Khandelwal Mukund , Vaish C. V. Sri , Kotecha Ketan 
Published: July 2022

Abstract
The fashion industry is rapidly expanding and playing a critical role in driving global economies. Due to this ever-growing industry, application of computer science is rising rapidly to solve different problems in this industry. Many e-commerce sites around the world allow their customers to purchase clothing items over the internet predominantly using recommender systems for shoppers based on the customer's purchase history, similar buying patterns of other shoppers, items in the wishlists and latest trends. These recommendation models lack personalization based on the user's body demographics. Since fashion is a way, one chooses to express themselves, it is important that each piece is carefully selected to suit the buyer. In this paper, an improved recommendation system is developed using a deep learning model for customers with different body shapes/types. It helps users to select clothing items based on their body shape. Proposed system is evaluated with respect to multiple deep learning models as well as traditional machine learning approaches. Xception model out performed by achieving 94% accuracy and a loss of 0.02%.
Infectious side effects of baricitinib: a big data analysis based on VigiBase
Authors: Mahroum Naim , Ozkan Mehmet Fatih , Abali Tunahan , Yilmaz Mesut , Bragazzi Nicola Luigi 
Published: July 2022

Abstract
Background and aim: baricitinib is an inhibitor of Janus-associated kinase (JAK) subtypes 1 and 2 with various effects on intracellular signaling pathways. Approved for rheumatoid arthritis (RA), and recently used for severe COVID-19, the prevalence of infections associated with baricitinib treatment has not been widely reported. We aimed to analyze the prevalence of infectious side effects in patients treated with baricitinib. Methods: using the WHO global pharmacovigilance database (VigiBase), we carried out an extensive data analysis of approximately 300 patients treated with baricitinib. The prevalence of infectious side effects was our main focus. Patients treated with baricitinib for the indication of severe COVID-19 were excluded.Results: the most prevalent infectious side effect of baricitinib was oral herpes (IC025 of 4.36) and herpes zoster infection (IC025 of 4.159). On the contrary, gastrointestinal viral infections, infectious pleural effusions and various viral pneumonias had low prevalence rates (IC025 values of 0.173; 0.093; and 0.188, respectively). Conclusion: based on a big data analysis, baricitinib was associated with infectious complications where oral herpes and herpes zoster infections shown to be more prevalent than previously reported. The immunomodulatory effect of baricitinib including cytokine effects on immune cells and the inhibition of numerous growth factors and cytokines such as IL-2, suppressing both innate and adaptive immune responses, are the most comprehensive mechanisms behind such side effects. Given the clinical indications for baricitinib (RA) and the current use in severe COVID-19, cautious approach should be taken before introducing baricitinib particularly in immunosuppressed patients.
Shore Protection Using Special Perforated Breakwater with Generating Renewable Energy
Authors: saie Yasser El 
Published: July 2022

Abstract
This paper presents an innovative vertical perforated breakwater for protecting shore line from Sea water wave energy and meanwhile converting the transmitted water wave energy to a renewable energy through some vents inside the body. This structure is composed of a vertically-faced shaped as rectangular with number of vents differ to be some ratios of porosities tested firstly as a wave energy dissipater by sign up the reading of the sensors of wave height before and after the seawall, and analyze the total energy transmitted to pushed it to an innovative system producing renewable electric energy, by adapting the location of these vents and changing the dimensions of these holes in three models with dimensions (8×4, 4×4, & 7×6 respectively, dimensions in cms). By choosing five heights of water depths (15, 19, 23, 27 & 31 cms) and four eccentricities of the wave maker, also recording the volt and ampere and finally the total percentage of wave energy that can be converted. These experiments were carried out in a recirculating open channel flume located at the Hydraulics Engineering Laboratory, at the Higher Institute of Engineering in El Shorouk City.
High-Performance and Balanced Parallel Graph Coloring on Multicore Platforms
Authors: Giannoula Christina , Peppas Athanasios , Goumas Georgios , Koziris Nectarios 
Published: July 2022

Abstract
Graph coloring is widely used to parallelize scientific applications by identifying subsets of independent tasks that can be executed simultaneously. Graph coloring assigns colors the vertices of a graph, such that no adjacent vertices have the same color. The number of colors used corresponds to the number of parallel steps in a real-world end-application. Therefore, the total runtime of the graph coloring kernel adds to the overall parallel overhead of the real-world end-application, whereas the number of the vertices of each color class determines the number of the independent concurrent tasks of each parallel step, thus affecting the amount of parallelism and hardware resource utilization in the execution of the real-world end-application.In this work, we propose a high-performance graph coloring algorithm, named ColorTM, that leverages Hardware Transactional Memory (HTM) to detect coloring inconsistencies between adjacent vertices. ColorTM detects and resolves coloring inconsistencies between adjacent vertices with an eager approach to minimize data access costs, and implements a speculative synchronization scheme to minimize synchronization costs and increase parallelism. We extend our proposed algorithmic design to propose a balanced graph coloring algorithm, named BalColorTM, with which all color classes include almost the same number of vertices to achieve high parallelism and resource utilization in the execution of the real-world end-applications.We evaluate ColorTM and BalColorTM using a wide variety of large real-world graphs with diverse characteristics. ColorTM and BalColorTM improve performance by 12.98x and 1.91x on average using 56 parallel threads compared to prior state-of-the-art approaches. Moreover, we study the impact of our proposed graph coloring algorithmic designs on a popular end-application, i.e., Community Detection, and demonstrate the ColorTM and BalColorTM can provide high performance improvements in real-world end-applications across various input data given.
Fracture, friction and damage processes in earthquake rupture zones
Authors: Ben-Zion Yehuda , Dresen Georg 
Published: July 2022

Abstract
We discuss properties and processes of earthquake rupture zones based on field studies, laboratory observations, theoretical models and simulations, with the goal of assessing the possible dominance of different processes in different parts of the rupture and validity of commonly used models. Rupture zones may be divided into front, intermediate, and tail regions that interact to different extents. The rupture front is dominated by fracturing and granulation processes and strong dilatation, producing faulting products that are reworked by subsequent sliding behind. The intermediate region sustains primarily frictional sliding with relatively high slip rates that produce appreciable stress transfer to the propagating front. The tail region further behind is characterized by low slip rates that effectively do not influence the propagating front, although it (and the intermediate region) can spawn small offspring rupture fronts. Earthquake ruptures are often spatially discontinuous and intermittent with a hierarchy of asperity and segment sizes that radiate waves with different tensorial composition and frequency bands. While different deformation processes dominating parts of the rupture zones can be treated effectively with existing constitutive relations, a more appropriate analysis of earthquake processes would require a model that combines aspects of fracture, damage-breakage, and frictional frameworks.
Acute Toxicity of Two Commonly Used Fungicides to Midwestern Amphibians
Authors: Hopkins Andrew , Hoverman Jason 
Published: July 2022

Abstract
Fungicide usage has increased globally in response to the rise in fungal pathogens, especially in the agricultural sector. Consequently, fungicides are not only increasingly found in water quality surveys, but they are also often the most detected pesticide type. However, research examining the toxicity of fungicides is still limited for many aquatic species. In this study, we examined the acute toxicity of two widely used fungicides, chlorothalonil and pyraclostrobin, on six larval amphibian species across multiple families using 96-h LC50 tests. We found that pyraclostrobin was approximately 3.5x more toxic than chlorothalonil; estimated LC50 values ranged from 5–18 µg/L for pyraclostrobin and 15–50 µg/L for chlorothalonil. Comparing across amphibian groups, we found that salamanders were 3x more sensitive to pyraclostrobin than anuran species and equally as sensitive to chlorothalonil. Notably, our estimated LC50 values are close in magnitude to the expected environmental concentration for these fungicides suggesting environmental exposures could lead to direct mortality in these species. Given the widespread and increasing usage of fungicides, additional work should be conducted to assess the general risk posed by these chemicals to amphibian and their associated aquatic habitats.
Associations between saliva and plasma cytokines and YKL-40 in cognitively-normal, older adults
Authors: Parkin Georgia M. , Kim Soyun , Mikhail Abanoub , McMillan Liv , Malhas Rond , Hollearn Martina , Granger Douglas A. , Mapstone Mark , Yassa Michael A. , Thomas Elizabeth A. 
Published: July 2022

Abstract
Inflammatory responses play key roles in the development and progression of many pathological conditions, including neurodegenerative conditions. Accurate quantification of inflammatory factors in saliva would be highly advantageous, given its convenience and non-invasive nature, enabling use as biomarkers for disease processes especially in older adults. However, few studies have attempted to validate salivary assays by directly comparing cytokine levels in blood and saliva samples the same individuals. In this study, we measured levels of 10 cytokines, interferon gamma (IFNg), interleukin (IL)-1 beta (IL-1b), IL-2, IL-4, IL-6, IL-8, IL-10, IL-12p70, IL-13 and tumor necrosis factor alpha (TNFa), as well as the inflammatory glycoprotein, YKL-40, in blood and saliva samples from a cohort of nondemented older adults (n = 71; 62% female; mean age 70.3 +/- 6.4 yrs; ) using sensitive electrochemiluminescence-based immunoassays. We found that the mean levels of all cytokines were higher in saliva compared to plasma, and specifically that levels of IL-1b, IL-2, IL-4, IL-12p70 and IL-13 in plasma were below the instrument detection limit for more than 50% of the subjects. We found strong sex differences in both saliva and plasma cytokines, with levels of several salivary cytokines, as well as YKL-40, showing higher concentrations in males compared to females. Comparing each cytokine between the two biofluids, we found that levels of IFNg, IL-6 and TNFa in blood were significantly correlated with their respective levels in saliva. We further observed that levels of these cytokines in blood were significantly correlated with additional cytokines in saliva, including IL-1b, IL-10, IL-8, IL12p70 and IL-13. These findings show that inflammatory markers in saliva are associated with those found in circulation, suggesting that inflammatory mechanisms between these two fluids are, at least to some extent, related. Consistent with prior work, several salivary markers were more likely to surpass the detection threshold than plasma markers, suggesting that salivary assays may, at least in some cases, be more useful for detecting physiological changes. Further our findings of robust sex differences in several salivary cytokines could have important implications for their potential use as health or disease biomarkers.
Dynamical behaviour of non-linear Kuramoto-Sivashinskyequation using integrated radial basis function networks
Authors: Bhanot Rajeev P. 
Published: July 2022

Abstract
In this research work, we implement the 1D-IRBFN method to find approximate solution of a very important non-linear partial differential equation (NLPDE) known as Kuramoto–Sivashinsky equation (KSE). The Crank–Nicolson formulation is used for time integration and the radial basis functions are used for the space discretization for KSE. We use the IRBFN method to solve two versions of KS equation, and then we compare numerical results with the exact solutions to demonstrate the accuracy of the method. The obtained solutions are in good agreement with the exact solutions. To visualize the dynamical behavior of KSE with different parameter values, we show graphical solutions and also compare the numerical solutions with few of results given in the recent research papers. To express the efficiency of the method, we calculate two types of errors in the numerical experiments (a) global relative error and (b) L2 error.Mathematics Subject Classification (2020) 74Sxx · 35G20