bluuebunny/crossref_metadata_2025_split huggingface dataset:
Support for bigger government: The principle‐implementation gap and COVID‐19
Authors: Goff Sandra H. , Ifcher John , Zarghamee Homa , Reents Alex , Wade Patrick 
Published: October 2022

AbstractWe study the COVID‐19 pandemic's effect on government and market attitudes using within‐subject comparisons of survey responses elicited before and after the onset of the pandemic. We find that participants develop significantly less favorable opinions toward government and markets; and that participants increase support for bigger government significantly and for redistribution, in general, marginally significantly. There is no evidence this leads to an increase in support for specific redistributive policies, nor for government to play a larger role in specific functions. Our results echo the stubbornness of American preferences for redistribution and suggest the presence of a principle‐implementation gap.
Tissue‐ and cell‐expression of druggable host proteins provide insights into repurposing drugs for COVID‐19
Authors: Li Jiapeng , Xue Yanling , Wang Xinwen , Smith Logan S. , He Bing , Liu Shuhan , Zhu Hao‐Jie 
Published: October 2022

AbstractSeveral human host proteins play important roles in the lifecycle of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Many drugs targeting these host proteins have been investigated as potential therapeutics for coronavirus disease 2019 (COVID‐19). The tissue‐specific expressions of selected host proteins were summarized using proteomics data retrieved from the Human Protein Atlas, ProteomicsDB, Human Proteome Map databases, and a clinical COVID‐19 study. Protein expression features in different cell lines were summarized based on recent proteomics studies. The half‐maximal effective concentration or half‐maximal inhibitory concentration values were collected from in vitro studies. The pharmacokinetic data were mainly from studies in healthy subjects or non‐COVID‐19 patients. Considerable tissue‐specific expression patterns were observed for several host proteins. ACE2 expression in the lungs was significantly lower than in many other tissues (e.g., the kidneys and intestines); TMPRSS2 expression in the lungs was significantly lower than in other tissues (e.g., the prostate and intestines). The expression levels of endocytosis‐associated proteins CTSL, CLTC, NPC1, and PIKfyve in the lungs were comparable to or higher than most other tissues. TMPRSS2 expression was markedly different between cell lines, which could be associated with the cell‐dependent antiviral activities of several drugs. Drug delivery receptor ICAM1 and CTSB were expressed at a higher level in the lungs than in other tissues. In conclusion, the cell‐ and tissue‐specific proteomics data could help interpret the in vitro antiviral activities of host‐directed drugs in various cells and aid the transition of the in vitro findings to clinical research to develop safe and effective therapeutics for COVID‐19.
Blood glucose response to running or cycling in individuals with type 1 diabetes: A systematic review and meta‐analysis
Authors: Eckstein Max L. , Aziz Faisal , Aberer Felix , Böckel Sina , Zimmer Rebecca T. , Erlmann Maximilian P. , Sourij Harald , Moser Othmar 
Published: October 2022

AbstractAimsThe aim of this systematic review and meta‐analysis was to assess how running and cycling influence the magnitude of blood glucose (BG) excursions in individuals with type 1 diabetes.MethodsA systematic literature search was conducted in EMBASE, PubMed, Cochrane Central Register of Controlled Trials, and ISI Web of Knowledge for publications from January 1950 until February 2021. Parameters included for analysis were population (adults and adolescents), exercise type, intensity, duration and insulin preparation. The meta‐analysis was performed to estimate the pooled mean with a 95% confidence interval (CI) of delta BG levels. In addition, sub‐group and meta‐regression analyses were performed to assess the influence of these parameters on delta BG.ResultsThe database search identified 3192 articles of which 69 articles were included in the meta‐analysis. Due to crossover designs within articles, 151 different results were included for analysis. Data from 1901 exercise tests of individuals with type 1 diabetes with a mean age of 29 ± 4 years were included. Overall, exercise tests BG decreased by −3.1 mmol/L [−3.4; −2.8] within a mean duration of 46 ± 21 min. The pooled mean decrease in BG for running was −4.1 mmol/L [−4.7; −2.4], whilst the pooled mean decrease in BG for cycling was −2.7 mmol/L [−3.0; −2.4] (p < 0.0001). Overall results can be found in Table S2.ConclusionsRunning led to a larger decrease in BG in comparison to cycling. Active individuals with type 1 diabetes should be aware that current recommendations for glycaemic management need to be more specific to the mode of exercise.
Fetal cardiac capillary hemangioma resulting in tachyarrhythmia
Authors: Sakamoto Yukifumi , Okada Seigo , Maekawa Ryo , Muneuchi Jun , Sugitani Yuichiro , Ochiai Yoshie , Kamimura Tetsuro , Joo Kunihiko , Onishi Yuji , Kobayashi Masaru , Kawakami Takeshi , Motoshita Junichi , Hasegawa Shunji 
Published: October 2022

AbstractWe present the case of a fetus with cardiac capillary hemangioma in the right atrial cavity. The tumor showed dramatic growth between the 28th and 32nd week of gestation and resulted in tachyarrhythmia. The patient was born at the 33 weeks of gestation weighing 2430 g via urgent cesarean section because the rapidly growing cardiac tumor caused incessant tachyarrhythmia, pericardial effusion, and fetal circulatory incompetence. Coronary angiography revealed that the right coronary artery drained into the tumor. Due to hemodynamic deterioration, the patient underwent subtotal resection of the tumor on the 2nd day after birth. Histopathological examination revealed an undifferentiated capillary hemangioma. The patient was discharged at the age of 86 days, as the tachyarrhythmia and hemodynamic incompetence had subsided; however, bradycardia and intermittent atrioventricular conduction disturbance gradually developed. Capillary hemangioma, a rare primary cardiac space‐occupying tumor in children, can invade the conduction system.
Living in an urban pod: Seed predation and parasitism of bruchid beetles in a native tree species
Authors: Galfrascoli Giovana María , Calviño Ana , Chiapero Ana Laura , Fenoglio María Silvina 
Published: October 2022

Abstract
Urbanisation is one of the main drivers of insect species loss worldwide. However, its impacts on ecological interactions involving insects still deserve further research, especially seed predation and parasitism of seed predators.
Here, we evaluated the seed predation rate by the specialist bruchid beetle Pseudopachymerina spinipes and its parasitism rate in the native tree Vachellia caven (Fabaceae) along an urbanisation gradient in Cordoba (Argentina). Since resource availability can influence these ecological interactions, we also investigated whether seed and prey availability could affect seed predation and parasitism rates, respectively.
We sampled trees in 10 sampling sites along an urbanisation gradient estimated by the Normalised Difference Vegetation Index (NDVI) within a 100 m radius. In our system, sites with low NDVI, beyond representing the low amount of vegetation cover, also indicate high surface temperature and low availability of host trees.
Seed predation in V. caven and the parasitism rate of P. spinipes were significantly reduced with increasing urbanisation. Notably, seed availability at the pod level did not affect seed predation rate, while prey availability was negatively correlated with parasitism rate.
These findings suggest a deleterious effect of urbanisation on the studied antagonistic interactions, giving no support to the idea of resource limitation effects.
Changes in soil silicon forms and availability as affected by rice straw and its biochar
Authors: Yao Donghui , Wu Jianfu , Gao Huiwen , Wu Duoji , Wei Zongqiang 
Published: October 2022

AbstractPhytogenic silica (PhSi) is suggested to control silicon (Si) cycling in soil–plant systems in tropical and subtropical regions. However, the role of crop residues and its biochar as a source of available Si has not been well investigated in agricultural soils. In our study, we determined and compared the effects of rice straw and its biochar on soil Si forms and Si availability. Soil Si forms were characterised by a sequential extraction method, and soil Si availability was assessed by rice growth and soil Si extraction methods. A soil incubation experiment showed that the addition of rice straw and biochar increased plant‐available Si in soil (including mobile Si and adsorbed Si), as well as soil amorphous Si (especially in rice straw treatments). Moreover, this increase was more significant when higher Si (e.g., Si added at the rates of 1.6 and 2.0 g kg−1 soil) was added via rice straw and its biochar, which is most likely a result of PhSi dissolution. Rice‐straw biochar, particularly at higher Si addition rates, tended to have a higher efficiency in increasing soil Si availability than rice straw, mainly due to its greater proportion of readily labile Si. A rice growth pot experiment showed that it is difficult to determine the extent of Si dissolution from PhSi in rice straw using a short‐term experiment with a normal single‐season straw return rate, where the increased pH played a more crucial role in regulating soil Si availability. Our results imply that, in terms of enhancing Si availability, long‐term biochar application with abundant Si input is more effective than straw retention for improving soil fertility in subtropical and tropical regions with highly weathered soils.Highlights
Effect of phytolith‐rich rice straw and its biochar on soil Si availability was studied.
Biochar had greater efficiency in increasing plant‐available Si in soil than rice straw.
Over the short term, Si dissolution from PhSi is insignificant with a typical single‐season straw return rate.
Increased pH played a crucial role in regulating soil Si availability in a short‐term study.
Contemporary tree growth shows altered climate memory
Authors: Peltier Drew M. P. , Anderegg William R. L. , Guo Jessica S. , Ogle Kiona 
Published: October 2022

AbstractTrees are long‐lived organisms, exhibiting temporally complex growth arising from strong climatic “memory.” But conditions are becoming increasingly arid in the western USA. Using a century‐long tree‐ring network, we find altered climate memory across the entire range of a widespread western US conifer: growth is supported by precipitation falling further into the past (+15 months), while increasingly impacted by more recent temperature conditions (−8 months). Tree‐ring datasets can be biased, so we confirm altered climate memory in a second, ecologically‐sampled tree‐ring network. Predicted drought responses show trees may have also become more sensitive to repeat drought. Finally, plots near sites with relatively longer precipitation memory and shorter temperature memory had significantly lower recent mortality rates (R2 = 0.61). We argue that increased drought frequency has altered climate memory, demonstrate how non‐stationarity may arise from failure to account for memory, and suggest memory length may be predictive of future tree mortality.
The EU external border as a site of preventive (in)justice
Authors: Mitsilegas Valsamis 
Published: October 2022

AbstractThe aim of the article is to fill a gap in the literature on the externalisation of immigration control by focusing not on practices of extraterritorial immigration control but on the externalisation of immigration control at the EU external border. The article will examine four parallel and inter‐related trends of preventive injustice on the border: the denial of law and pushbacks, and their handling by judicial authorities and EU institutions and agencies; the emerging framework of the instrumentalisation of migration; the normalisation of border procedures based on the fiction of ‘non‐entry’; and detention of third‐country nationals at the border, to back up non‐entry policies. The article will highlight the rule of law deficit such externalisation entails.
A Self‐adaptive Bald Eagle Search optimization algorithm with dynamic opposition‐based learning for global optimization problems
Authors: Sharma Suvita Rani , Kaur Manpreet , Singh Birmohan 
Published: October 2022

AbstractBald Eagle Search optimization (BES) is introduced recently, which mimics the bald eagles' hunting and food searching behaviour. The capability of a BES algorithm is enhanced in this paper by avoiding local optima stagnation and premature convergence problems. The BES algorithm is modified to enhance the performance of the algorithm and the modified algorithm is called the Self Adaptive Bald Eagle Search (SABES) algorithm. Dynamic‐opposite Learning (DOL) method is invoked in the initialization phase to increase the population diversity and convergence speed. To find better global solutions, the exploitation capability of the SBES algorithm is enhanced by considering the dynamic‐opposite solutions. In addition, the algorithmic parameter values of the BES algorithm have been determined using the linear and non‐linear time‐varying adaption strategy to create a balance between the search abilities which promotes the overall performance of the algorithm. The performance of the SABES algorithm is validated by comparing the results of 50 benchmark functions and CEC2017 functions with different erstwhile algorithms. The proposed algorithm achieves the best results in 80% of the benchmark functions, whereas the BES only gets the best results in 56% of functions. For the CEC2017, the SABES algorithm achieves optimal results for 20 functions which are highest in comparison to state‐of‐the‐art algorithms. The feasibility and effectiveness of the proposed algorithm are checked using the 15 CEC2020 competition real‐world single‐objective constrained optimization problems. The SABES achieves a 100% success rate and 100% feasibility rate in comparison to other well‐regarded algorithms. The statistical significance of the algorithm has been proved using Friedman's mean rank and Wilcoxon sign rank test.
Maize CDKA2;1a and CDKB1;1 kinases have different requirements for their activation and participate in substrate recognition
Authors: López‐Hernández Mingyar N. , Vázquez‐Ramos Jorge M. 
Published: October 2022

Cyclin‐dependent kinases (CDKs), in association with cyclins, control cell cycle progression by phosphorylating a large number of substrates. In animals, activation of CDKs regularly requires both the association with a cyclin and then phosphorylation of a highly conserved threonine residue in the CDK activation loop (the classical mechanism), mediated by a CDK‐activating kinase (CAK). In addition to this typical mechanism of activation, some CDKs can also be activated by the association of a cyclin to a monomeric CDK previously phosphorylated by CAK although not all CDKs can be activated by this mechanism. In animals and yeast, cyclin, in addition to being required for CDK activation, provides substrate specificity to the cyclin/CDK complex; however, in plants both the mechanisms of CDKs activation and the relevance of the CDK‐associated cyclin for substrate targeting have been poorly studied. In this work, by co‐expressing proteins in E. coli, we studied maize CDKA2;1a and CDKB1;1, two of the main types of CDKs that control the cell cycle in plants. These kinases could be activated by the classical mechanism and by the association of CycD2;2a to a phosphorylated intermediate in its activation loop, a previously unproven mechanism for the activation of plant CDKs. Unlike CDKA2;1a, CDKB1;1 did not require CAK for its activation, since it autophosphorylated in its activation loop. Phosphorylation of CDKB1;1 and association of CycD2;2 was not enough for its full activation as association of maize CKS, a scaffolding protein, differentially stimulated substrate phosphorylation. Our results suggest that both CDKs participate in substrate recognition.
Niche width predicts extinction from climate change and vulnerability of tropical species
Authors: Grinder Rollie M. , Wiens John J. 
Published: October 2022

AbstractClimate change may be a major threat to global biodiversity, especially to tropical species. Yet, why tropical species are more vulnerable to climate change remains unclear. Tropical species are thought to have narrower physiological tolerances to temperature, and they have already experienced a higher estimated frequency of climate‐related local extinctions. These two patterns suggest that tropical species are more vulnerable to climate change because they have narrower thermal niche widths. However, no studies have tested whether species with narrower climatic niche widths for temperature have experienced more local extinctions, and if these narrower niche widths can explain the higher frequency of tropical local extinctions. Here, we test these ideas using resurvey data from 538 plant and animal species from 10 studies. We found that mean niche widths among species and the extent of climate change (increase in maximum annual temperatures) together explained most variation (>75%) in the frequency of local extinction among studies. Surprisingly, neither latitude nor occurrence in the tropics alone significantly predicted local extinction among studies, but latitude and niche widths were strongly inversely related. Niche width also significantly predicted local extinction among species, as well as among and (sometimes) within studies. Overall, niche width may offer a relatively simple and accessible predictor of the vulnerability of populations to climate change. Intriguingly, niche width has the best predictive power to explain extinction from global warming when it incorporates coldest yearly temperatures.
Modeling activity spaces using big geo‐data: Progress and challenges
Authors: Yuan Yihong , Xu Yang 
Published: October 2022

AbstractThe growing availability of big geo‐data, such as mobile phone data and location‐based social media (LBSM), provides new opportunities and challenges for modeling human activity spaces in the big data era. These datasets often cover a large sample size and can be used to model activity spaces more efficiently than traditional travel surveys. However, these data also have inherent limitations, such as the lack of reliable demographic information of individuals and a low sampling rate. This paper first reviews the strengths and weaknesses of various internal and external activity space indicators. We then discuss the pros and cons of using various new data sources (e.g., georeferenced mobile phone data and LBSM data) for activity space modeling. We believe this review paper is a valuable reference not only for researchers who are interested in activity space modeling based on big geo‐data, but also for planners and policy makers who are looking to incorporate new data sources into their future workflow.
Women's inclusion and neoliberal governmentality in the Swedish digital game industry: An analysis of discursive positions and recruitment strategies
Authors: Szczepanska Anna Maria 
Published: October 2022

AbstractMany companies within the creative industries present themselves as open and egalitarian while they are, at the same time, marked by vertical and horizontal sex‐segregation. The paper illustrates how this is particularly salient in the digital games industry and further examines how the presence of a neoliberal postfeminist discourse contributes to the neglectance of structured inequality. The analysis is based on qualitative interviews with actors in the Swedish games industry. Drawing on the theoretical perception that neoliberal logic reframes contemporary notions of gender and equality through a postfeminist discursive framework, this paper identifies and critically discusses different approaches to understand and tackle the gender divide in the Swedish games industry. While postfeminism has been characterized as apolitical or even anti‐feminist, this paper discusses how such postfeminist expressions could also be understood as connecting to the feminist project of de‐gendering. By way of conclusion, this study shows how a postfeminist discourse obscures the reality of gendered inequalities and poses limits to organizational change.
Severe hypertriglyceridemia in an infant on chronic hemodialysis
Authors: Aly Rasha , Acharya Ratna , Upadhyay Kiran K. 
Published: October 2022

AbstractSevere hyperlipidemia is a risk factor for cardiovascular disease. Children with chronic kidney disease and end stage renal disease are at risk for development of hyperlipidemia. In this report, we describe a 7‐month‐old male infant with Denys–Drash syndrome who was found to have a “milky‐layer” floating on the deaerator of the hemodialysis machine. Investigations showed severe hypertriglyceridemia of >1000 mg/dl. The patient had been on chronic continuous manual peritoneal dialysis until 6 months of age and recently had been switched to hemodialysis. Management included lowering of caloric intake and addition of medium chain triglyceride with reduction of the serum triglyceride levels to 300–400 mg/dl. Close monitoring of serum lipids and timely intervention is important to prevent serious complications associated with dyslipidemia. Observation of the “milky layer” in the deaerator of the hemodialysis machine may be an interesting visual clue of underlying severe hypertriglyceridemia.
Recent trends of advanced ceramics industry and Fine Ceramics Roadmap 2050
Authors: Takemura Hirofumi , Fukushima Hideko 
Published: October 2022

AbstractJapan's fine ceramics (advanced ceramics) industry, which reached US$30 billion of production in 2018 (an annual growth rate of 6.3%), accounts for 40% of the global market. The mission of the Japan Fine Ceramics Association (JFCA), which consists of 116 corporate members related to fine ceramics, is to further promote the development of this industry. In this paper, we describe the recent trends of fine ceramics industry and the latest JFCA's activities, including the publication of the FC Roadmap 2050 (2021 edition). This roadmap addresses fine ceramics technologies and products that will meet increasingly diverse needs of society, market, and industry in the year 2050.
The adaptation of the Nurse Turnover Intention Scale into Turkish: A validity and reliability study
Authors: Zeyrek Arife Şanlıalp , Fidan Özlem , Köktaş Nesrin Çunkuş 
Published: October 2022

AbstractAimThe aim of this study was to adapt the Nurse Turnover Intention Scale to Turkish and test its validity and reliability.MethodsThis methodological study was conducted with 200 nurses. The Personal Information Form and the Nurse Turnover Intention Scale were used for data collection between November and December 2021. Language and content validity, explanatory and confirmatory factor analysis, criterion validity, Cronbach's alpha coefficient, item–total score correlation and test–retest reliability methods were used for the validity and reliability analysis of the scale.ResultsExploratory factor analysis showed that the Nurse Turnover Intention Scale had a single factor. Its single factor structure was confirmed using confirmatory factor analysis. Cronbach's alpha coefficient of the scale was 0.902, and factor loading was between 0.60 and 0.78. Statistical analyses indicated that each item in the Turkish version of the scale had a high internal consistency. The test–retest correlation value was found as p < 0.05.ConclusionThe Nurse Turnover Intention Scale has been confirmed to be a suitable, valid and reliable measurement tool for Turkish society. Nurse turnover intention is the most powerful predictor of actual turnover within the nursing profession. This scale will help to easily attain valid and reliable outcomes.