bluuebunny/crossref_metadata_2025_split huggingface dataset:
Paradigm shift in the sustainability of water-based power sector – an application of Hydropower sustainability assessment protocol
Authors: Chhabra Roy Neha , Roy N.G. 
Published: April 2022

Purpose
The study aims to identify the severe socioeconomic, environmental, and ecological impacts caused by the construction of mega and large hydro-power plants in Uttarakhand, India. In addition to identifying the attributes, the study creates an integrated index that will assist in the development of sustainable hydro-power.

Design/methodology/approach
The methodology used for this impact identification was based on extensive literature review, focused expert discussions and further validation through a primary survey among the stakeholders in the hydropower sector. The sustainability index (SI) was estimated using the fuzzy logic theory.

Findings
The study area SI shows that few projects are in extreme zones, and through suggestive measures, few project sites can be made viable for long-term sustainable project site. A Hydropower Sustainability Assessment Protocol–based conceptual model is also proposed for mitigation of impacts.

Originality/value
Hydropower plays an essential role in access to cleaner and cheaper sources of energy; it defines the usage of water resources toward inflation-free green energy and holds spectacular operational flexibility. Despite the significant advantages associated with hydroelectric power projects, there are adverse side effects as well. The water-based power sector industry contributes to any nation through both economic and environmental ways. Although one-third of the power business in India is carried out through water-based hydropower projects, recent trends in water-based hydropower projects show significant socioeconomic and environmental impacts that create a debate about the sustainability of these projects.
What is the relationship between quality of working life, work–life balance and quality of life?
Authors: Su Zhiwei , Zabilski Aleksander 
Published: April 2022

PurposeThe study investigates the relationship between quality of work life (QWL), work–life balance (WLB) and quality of life (QoL), with reference to corporate social responsibility (CSR) approaches used at the Shangri-La, B&B and Rui hotel companies.Design/methodology/approachThe study draws on the literature and on comparative case study analysis of three very different companies.Findings The findings indicate that CSR practices have a positive impact on QoL, regardless of company size, location or type of initiative, and that they underline the importance of education as a key to success.Originality/valueThis article concentrates on the concept of QoL and explores different applications of the idea in various environments.
The relative influence of cross‐seasonal and local weather effects on the breeding success of a migratory songbird
Authors: de Zwaan Devin R. , Drake Anna , Camfield Alaine F. , MacDonald Elizabeth C. , Martin Kathy 
Published: April 2022

Abstract

In seasonal environments, fluctuating early‐season weather conditions and short breeding windows limit reproductive opportunities such that breeding earlier or later than the optimum may be particularly costly. Given the risk of early‐season energy limitations, time‐ and energy‐based carry‐over effects stemming from environmental conditions across the annual cycle may have pronounced consequences for breeding phenology and fitness. Generally, when and where environmental conditions are most influential are poorly understood, limiting our ability to predict the future of climate‐sensitive populations.

For an alpine‐breeding, migratory population of horned lark Eremophila alpestris in northern British Columbia, Canada (54.8°N), we assessed how weather conditions across the annual cycle influenced clutch initiation date and offspring development. We also addressed how cross‐seasonal effects on breeding parameters combine to influence reproductive fitness.

With 12 years of breeding data and 3 years of migration data, we used a sliding window approach to identify points during the annual cycle when weather events most influenced breeding phenology and offspring development. Consequences for breeding success were assessed using nest survival simulations.

Average clutch initiation date varied up to 11 days among years but did not advance from 2003 to 2019. Warmer temperatures at stopover and breeding sites advanced clutch initiation, but winter conditions had no effect. Sub‐zero stopover temperatures carried over to prolong offspring development independent of clutch initiation date, potentially indicating energy‐based carry‐over effects acting on parental investment. Nest survival decreased with both later clutch initiation and prolonged offspring development such that females nesting earlier and fledging offspring at a younger age were up to 45% more likely to reproduce successfully.

We demonstrate that stronger carry‐over effects originated from environmental conditions closer to the breeding site in time and space, as well as the potential for energy‐based mechanisms to link pre‐breeding conditions to reproductive fitness. We also highlight the importance of extended stopovers for songbirds breeding in seasonal environments, particularly given that climatic conditions are becoming increasingly decoupled across stages of the annual cycle. Understanding the cross‐seasonal mechanisms shaping breeding decisions in stochastic environments allows for more accurate predictions of population‐level responses to climate change.
Changes in economic outcomes before and after rural hospital closures in the United States: A difference‐in‐differences study
Authors: Chatterjee Paula , Lin Yuqing , Venkataramani Atheendar S. 
Published: April 2022

AbstractObjectiveThe objective of this study is to assess changes in local economic outcomes before and after rural hospital closures.Data SourcesRural hospital closures from January 1, 2005, to December 31, 2018, were obtained from the Sheps Center for Health Services Research. Economic outcomes from this same period were obtained from the Bureau of Labor Statistics, Bureau of Economic Analysis, Quarterly Workforce Indicators, U.S. Federal Reserve Economic Data, RAND Corporation state statistics database, U.S. Social Security Administration, and U.S. Census Bureau.DesignDifference‐in‐differences study of 2094 rural counties.Data Collection/ExtractionThe primary exposure was county‐level rural hospital closures. The primary outcomes were county‐level unemployment rates; employment‐population ratios; labor force participation‐population ratios; per capita income; total jobs; health care sector jobs; disability program participation‐population ratios; percent of the population with subprime credit scores; total filings for bankruptcies per 1000 population; and population size.Principal FindingsA total of 104 rural counties experienced a hospital closure, compared to 1990 rural counties that did not. Rural hospital closures were associated with significant reductions in health care sector employment (−13.8%; 95% CI: −22%, −5.6%; p < 0.001), but not with changes in any other economic measure. For unemployment rates, employment‐population ratios, per capita income, disability program participation‐population ratios, and total jobs, we found evidence of adverse trends preceding hospital closures. Findings were robust to adjusting for county‐specific time trends, specifying exposure at the commuting zone‐level, and using alternate definitions of rurality to define sample counties.ConclusionWith the exception of a decline in jobs within the health care sector, there was no association between rural hospital closures and county‐level economic outcomes. Instead, economic conditions were already declining in counties experiencing closures compared to those that did not.
Colonization of nasal cavities by Staphylococcus epidermidis mitigates SARS‐CoV‐2 nucleocapsid phosphoprotein‐induced interleukin (IL)‐6 in the lung
Authors: Kao Ming‐Shan , Yang Jen‐Ho , Balasubramaniam Arun , Traisaeng Supitchaya , Jackson Yang Albert , Yang John Jackson , Salamon Benjamin Prethiviraj , Herr Deron R. , Huang Chun‐Ming 
Published: April 2022

SummaryInfection by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can trigger excessive interleukin (IL)‐6 signalling, leading to a myriad of biological effects including a cytokine storm that contributes to multiple organ failure in severe coronavirus disease 2019 (COVID‐19). Using a mouse model, we demonstrated that nasal inoculation of nucleocapsid phosphoprotein (NPP) of SARS‐CoV‐2 increased IL‐6 content in bronchoalveolar lavage fluid (BALF). Nasal administration of liquid coco‐caprylate/caprate (LCC) onto Staphylococcus epidermidis (S. epidermidis)‐colonized mice significantly attenuated NPP‐induced IL‐6. Furthermore, S. epidermidis‐mediated LCC fermentation to generate electricity and butyric acid that promoted bacterial colonization and activated free fatty acid receptor 2 (Ffar2) respectively. Inhibition of Ffar2 impeded the effect of S. epidermidis plus LCC on the reduction of NPP‐induced IL‐6. Collectively, these results suggest that nasal S. epidermidis is part of the first line of defence in ameliorating a cytokine storm induced by airway infection of SARS‐CoV‐2.
phenofit: An R package for extracting vegetation phenology from time series remote sensing
Authors: Kong Dongdong , McVicar Tim R. , Xiao Mingzhong , Zhang Yongqiang , Peña‐Arancibia Jorge L. , Filippa Gianluca , Xie Yuxuan , Gu Xihui 
Published: April 2022

Abstract

Satellite‐derived vegetation indices (VIs) provide a way to analyse vegetation phenology over decades globally. However, these data are often contaminated by different kinds of optical noise (e.g. cloud, cloud shadow, snow, aerosol), making accurate phenology extraction challenging.

We present an open‐source state‐of‐the‐art R package called to extract vegetation phenological information from satellite‐derived VIs. adopts state‐of‐the‐art phenology extraction methods, such as a weight updating function for reducing optical noise contamination, a growing season division function for separating the VI time series into different vegetation cycles, and rough and fine fitting functions for reconstructing VI time series. They work together to make phenology extraction from frequently contaminated VIs easier and more accurate.

Compared against other widely used phenology extraction tools, for example, and , provides flexible input and output options, a practical growing season division function, rich curve fitting and phenology extraction functions, and robust performance under different kinds of optical noise.

In addition to working with VIs from mesoscale satellites (e.g. MODIS and AVHRR), can also reconstruct vegetation time series and extract phenology using other sources, such as VIs from high‐resolution optical satellites (e.g. Sentinel‐2 and Landsat) and radar satellites (e.g. Sentinel‐1), vegetation greenness indices from digital cameras and gross primary production estimations from eddy‐covariance sites. As such, can contribute to the study of ecological process dynamics and assist in effective modelling of global change impacts on vegetation, as caused by climate variability and human intervention. Code and data of case studies are available at https://zenodo.org/record/6425745 (Kong, 2022a).
Accounting and social capital: A review and reflections on future research opportunities
Authors: de Villiers Charl , La Torre Matteo , Botes Vida 
Published: April 2022

AbstractWe explore how the concept of social capital is used and theorised in accounting research by performing a structured literature review, and a critical analysis, of articles published in leading accounting journals. We identify two research paths, namely (1) how social capital influences accounting, and (2) how accounting influences social capital formation. We highlight that both accounting and social capital emanate from the social connections between individuals. We conclude that, although social capital is important in accounting, it is still under‐researched. This provides research opportunities for theory development, and interdisciplinary perspectives. We offer several further suggestions for future research.
The effects of social isolation due to COVID‐19 on the fear of movement, falling, and physical activity in older people
Authors: Atıcı Emine , Girgin Nuray , Çevik Saldıran Tülay 
Published: April 2022

AbstractObjectiveThis study investigates the interaction between fear of movement, fall risk, and physical activity levels in ageing individuals who experienced social isolation during the COVID‐19 pandemic.MethodsIn this descriptive and cross‐sectional study, 254 eligible participants used an online background survey. Individuals’ fear of movement was evaluated by the kinesiophobia causes scale, fall risk by the falls efficacy scale, and physical activity levels by the physical activity scale for the ageing.ResultsThe fear of movement had a significant positive interaction on fall risk (β = 0.471, R2 = 0.495, p < 0.001). The fall risk had a negative effect on physical activity (β = −1.686, R2 = 0.161, p < 0.001). The fear of movement and fall risk explained 15.6% of the change in physical activity levels of ageing individuals (p < 0.001).ConclusionsThese results showed a significant interaction between physical activity levels and fear of movement, with a high fall risk in ageing individuals during the pandemic period.
Circadian rhythm affects the magnitude of contact hypersensitivity response in mice
Authors: Miyake Toshiya , Egawa Gyohei , Chow Zachary , Asahina Ryota , Otsuka Masayuki , Nakajima Saeko , Nomura Takashi , Shibuya Rintaro , Ishida Yoshihiro , Nakamizo Satoshi , Murata Teruasa , Kitoh Akihiko , Kabashima Kenji 
Published: April 2022

AbstractBackgroundThe circadian rhythm controls multiple biological processes, including immune responses; however, its impact on cutaneous adaptive immune response remains unclear.MethodsWe used a well‐established cutaneous type IV allergy model, contact hypersensitivity (CHS). We induced CHS using dinitrofluorobenzene (DNFB). Mice were sensitized and elicited with DNFB in the daytime or at night.ResultsIn mice, a nocturnally active animal, we found that ear swelling increased when mice were sensitized at night compared with in the daytime. In addition, cell proliferation and cytokine production in the draining lymph nodes (LNs) were promoted when sensitized at night. We hypothesized that these differences were due to the oscillation of leukocyte distribution in the body through the circadian production of adrenergic hormones. Administration of a β2‐adrenergic receptor (β2AR) agonist salbutamol in the daytime decreased the number of immune cells in blood and increased the number of immune cells in LNs. In contrast, a β2AR antagonist ICI18551 administration at night increased the number of immune cells in blood and decreased the number of immune cells in LNs. Accordingly, the severity of CHS response was exacerbated by salbutamol administration in the daytime and attenuated by ICI18551 administration at night.ConclusionOur study demonstrated that the magnitude of adaptive CHS response depends on the circadian rhythm and this knowledge may improve the management of allergic contact dermatitis (ACD) in humans.
Resting state networks mediate the association between both cardiovascular fitness and gross motor skills with neurocognitive functioning
Authors: Meijer Anna , Königs Marsh , Pouwels Petra J.W. , Smith Joanne , Visscher Chris , Bosker Roel J. , Hartman Esther , Oosterlaan Jaap 
Published: April 2022

AbstractRecent evidence suggests that cardiovascular fitness and gross motor skill performance are related to neurocognitive functioning by influencing brain structure and functioning. This study investigates the role of resting‐state networks (RSNs) in the relation of cardiovascular fitness and gross motor skills with neurocognitive functioning in healthy 8‐ to 11‐year‐old children (n = 90, 45 girls, 10% migration background). Cardiovascular fitness and gross motor skills were related to brain activity in RSNs. Furthermore, brain activity in RSNs mediated the relation of both cardiovascular fitness (Frontoparietal network and Somatomotor network) and gross motor skills (Somatomotor network) with neurocognitive functioning. The results indicate that brain functioning may contribute to the relation between both cardiovascular fitness and gross motor skills with neurocognitive functioning.
Risk taking propensity: Nurse, surgeon and patient preferences for diverting ileostomy
Authors: Mackay Ian , Clark David A. , Nicholson James , Edmundson Aleks , Steffens Daniel , Solomon Michael 
Published: April 2022

AbstractAimThe decision‐making process to defunction a pelvic colorectal anastomosis involves complex heuristics and is framed by surgeon personality factors. Risk taking propensity may be an important factor in these decisions and patient preferences have not been evaluated alongside surgeons and nurses.MethodsA prospective cross‐sectional study involving a one‐off interview and questionnaire assessing how risk taking propensity affects nurse, surgeon and patient preferences for a temporary defunctioning ileostomy (TDI) was performed. The risk taking index (RTI) was employed to evaluate risk taking propensity and the validated prospective measures of preference instruments to evaluate preferences for stoma avoidance in several scenarios by asking the individual to consider trading or gambling years of remaining life expectancy.ResultsOne hundred and fifty participants met the inclusion criteria, which included 30 (20.0%) surgical nurses, 20 (13.3%) colorectal surgeons and 100 (66.7%) patients. Surgeons had a significantly higher RTI (mean ± SD: 26.8 ± 6.7) than patients (mean ± SD: 20.0 ± 9.8) and nurses (mean ± SD: 23.0 ± 6.6) p = 0.002. Surgeons would consider that it would be in a patient's best interest to have a TDI at an AL rate of 15% or greater, whereas nurses and patients would do so at 28% and 25%, respectively (p = 0.007).ConclusionSurgeons were shown to have a higher risk taking propensity than patients and nurses but a significantly lower threshold of AL where they would consider a TDI is in the best interest of the patient.
Effects of the COVID‐19 pandemic on clinically diagnosed psychiatric disorders in persons with type 2 diabetes
Authors: Kowall Bernd , Kostev Karel , Landgraf Rüdiger , Hauner Hans , Bierwirth Ralf , Rathmann Wolfgang 
Published: April 2022

AbstractAimsTo examine whether the incidence rates of diagnosed depression, anxiety disorders and stress reactions, as well as prescription rates of antidepressants and anxiolytics were higher during the COVID‐19 pandemic than before in persons with type 2 diabetes in Germany. Contrary to earlier studies, clinical diagnoses of psychiatric disorders (ICD classification) were used.MethodsThe German Disease Analyzer (DA) database is an outpatient database containing routine data on patients´ diseases and treatments provided by a representative panel of physician practices selected from across Germany. We assessed incidence rates of depressive disorders (ICD‐10: F32, F33), anxiety disorders (F41) and stress reactions (F43) in quarters from January 2019 to March 2021 in 95,765 people with type 2 diabetes included in the DA in 2019 (mean age 68.9 years, 58% men). Prescription rates of antidepressants and anxiolytics in quarters from January 2020 to March 2021 were compared with prescription rates from 1 year earlier.ResultsDuring the study period, the incidence rate of newly diagnosed depressive disorders in persons with type 2 diabetes declined slightly, while the incidence rates of anxiety and stress disorders remained largely constant. The rates of new prescriptions for antidepressants and anxiolytics were lower in all quarters of 2020 and in the first quarter of 2021 than in the quarters 1 year earlier. Diabetes‐related complications were more prevalent in persons with incident psychiatric disorders than in those without.ConclusionsNo increase in the incidence rates of clinically diagnosed psychiatric disorders was observed during the COVID‐19 pandemic in Germany in persons with type 2 diabetes.
The contribution of neuropathology to multiple sclerosis research
Authors: Lassmann Hans 
Published: April 2022

AbstractBackground and purposeNeuropathology plays a major role in deciphering disease mechanisms in multiple sclerosis (MS). This review article describes recent advances in neuropathological research related to inflammatory demyelinating diseases.MethodsA retrospective review of neuropathological studies published during the last two decades was conducted.ResultsThe importance of neuropathology is generally seen in its contribution to the diagnosis of diseases of the nervous system and, in particular, in neuro‐oncology. However, when it also includes analysis of the global three‐dimensional extension of brain damage and the temporal sequence of lesion evolution and relates this to molecular changes in the lesions, it offers the potential to decipher disease pathogenesis and to contribute to the development of effective and causative treatments. In MS research, neuropathology has been essential in discriminating the disease from other inflammatory autoimmune or demyelinating diseases, such as neuromyelitis optica spectrum disorders (NMOSD) or myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD). It defined the hallmark of chronic progressive disease in MS patients as slowly expanding tissue damage, which occurs not only within and around lesions but also in the normal appearing white and gray matter. It showed that these changes occur in the course of a tissue‐resident immune response within the central nervous system, involving tissue‐resident effector memory cells and plasma cells. Molecular studies in neuropathologically defined micro‐dissected MS lesions identified a cascade of oxidative injury, mitochondrial damage and subsequent virtual hypoxia as a major pathway of tissue injury in MS.ConclusionsThe results of these studies were highly relevant for the identification of potential therapeutic targets in MS patients and the design of pivotal clinical trials.
Association between family history of alcohol use disorder and catamenial epilepsy
Authors: Herzog Andrew G. 
Published: April 2022

AbstractThe purpose of this investigation was to determine whether a family history of alcohol use disorder (AUD) might be a risk factor and possible clinical biomarker for catamenial epilepsy. The retrospective case–control data came from 119 women, aged 13–48 years, with intractable seizures. We report the relative risk for positive family history of AUD among women with catamenial epilepsy (Group 1) relative to women with noncatamenial epilepsy (Group 2). The risk ratio (RR) for positive AUD history for Group 1 (n = 59) relative to Group 2 (n = 60) was 3.46 (95% confidence interval = 1.36–8.76, p = .009). The RRs were significant for women who had the (C1) perimenstrual (p = .009) and (C3) entire luteal phase (p = .003) patterns but not the (C2) preovulatory pattern. AUD history had a high specificity of 91.7% (55/60) but relatively low sensitivity of 28.8% (17/59) for the prediction of catamenial epilepsy. The positive predictive value was 77.3% (17/22), whereas the negative predictive value was 56.7% (55/97). AUD history is a highly specific biomarker for catamenial epilepsy but has relatively low sensitivity for its detection. Further investigation may identify additional biomarkers that are more efficient than seizure–menses calendars.