bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fog computing application of cyber-physical models of IoT devices with symbolic approximation algorithms
Authors: Choi Deok-Kee 
Published: October 2022

AbstractSmart manufacturing systems based on cloud computing deal with large amounts of data for various IoT devices, resulting in several challenges, including high latency and high bandwidth usage. Since fog computing physically close to IoT devices can alleviate these issues, much attention has recently been focused on this area. Fans are nearly ubiquitous in manufacturing sites for cooling and ventilation purposes. Thereby, we built a fan system with an accelerometer installed and monitored the operating state of the fan. We analyzed time-series data transmitted from the accelerometer. We applied machine learning under streaming data analytics at the fog computing level to create a fan’s cyber-physical model (CPM). This work employed the symbolic approximation algorithm to approximate the time series data as symbols of arbitrary length. We compared the performance of CPMs made with five time-series classification (TSC) algorithms to monitor the state of the fan for anomalies in real time. The CPM made with the BOSS VS algorithm, a symbol approximation algorithm, accurately determined the current state of the fan within a fog computing environment, achieving approximately 98% accuracy at a 95% confidence level. Furthermore, we conducted a posthoc analysis, running statistical rigor tests on experimental data and simulation results. The workflow proposed in this work would be expected to be utilized for various IoT devices in smart manufacturing systems.
The CIVISANO protocol: a mixed-method study about the role of objective and perceived environmental factors on physical activity and eating behavior among socioeconomically disadvantaged adults
Authors: D’Hooghe Suzannah , Inaç Yasemin , De Clercq Eva , Deforche Benedicte , Dury Sarah , Vandevijvere Stefanie , Van de Weghe Nico , Van Dyck Delfien , De Ridder Karin 
Published: October 2022

Abstract
Background
Overweight and obesity have a strong socioeconomic profile. Unhealthy behaviors like insufficient physical activity and an unbalanced diet, which are causal factors of overweight and obesity, tend to be more pronounced in socioeconomically disadvantaged groups in high income countries. The CIVISANO project aims to identify objective and perceived environmental factors among different socioeconomic population groups that impede or facilitate physical activity and healthy eating behavior in the local context of two peri-urban Flemish municipalities in Belgium. We also aim to identify and discuss possible local interventions and evaluate the participatory processes of the project.

Methods
This study (2020–2023) will use community-based participatory tools, involving collaborative partnerships with civic and stakeholder members of the community and regular exchanges among all partners to bridge knowledge development and health promotion for socioeconomically disadvantaged citizens. Furthermore, a mixed-methods approach will be used. A population survey and geographic analysis will explore potential associations between the physical activity and eating behaviors of socioeconomically disadvantaged adults (25–65 years old) and both their perceived and objective physical, food and social environments. Profound perceptive context information will be gathered from socioeconomically disadvantaged adults by using participatory methods like photovoice, walk-along, individual map creation and group model building. An evaluation of the participatory process will be conducted simultaneously.

Discussion
The CIVISANO project will identify factors in the local environment that might provoke inequities in adopting a healthy lifestyle. The combination of perceived and objective measures using validated strategies will provide a robust assessment of the municipality environment. Through this analysis, the project will investigate to what extent community engagement can be a useful strategy to reduce health inequities. The strong knowledge exchange and capacity-building in a local setting is expected to contribute to our understanding of how to maximize research impact in this field and generate evidence about potential linkages between a health enhancing lifestyle among socioeconomically disadvantaged groups and their physical, food and social environments.
Forensic investigation of microtraces on an item of Dutch eighteenth century clothing in the Rijksmuseum collection
Authors: Goedhart Yoram Ray , Keune Katrien , Meijer Suzan , van Asten Arian 
Published: October 2022

Abstract
Most garments in museum collections have belonged to people of high societal status. Clothing of the common people, however, has rarely been preserved. Because of this, the conservation of such rare items is of special importance. The current study focuses on such an object from the Rijksmuseum collection; a pair of eighteenth century breeches that were retrieved from an anonymous grave on Spitsbergen. As these breeches contain several unidentified materials, it is unclear how best to conduct the conservation of the object. The identification of trace material plays a key role within criminal law and therefore, it is hypothesized that a forensic approach could provide a suitable framework within this case of cultural heritage as well. After forensic examination, trace material was analyzed using a microscopy-based approach and was found to be mainly of biological origin. Energy-dispersive X-ray (EDX) and Attenuated Total Reflection Fourier Transform Infrared (ATR-FTIR) spectroscopy indicated the presence of human skin remains. It was concluded that a modern forensic approach can successfully be applied to a historical object within cultural heritage and can assist decision-making regarding possible future conservation of the object. The systematic application of the forensic methodology was found to be appropriate with little to no modification to classify and identify trace materials, but further improvements could be made. The current work should be seen as a starting point that allows for more questions regarding museum objects to be answered in a forensic manner, including aspects such as authenticity, the chain of custody, the context, original use and object conservation.
Health supply chain system in Uganda: assessment of status and of performance of health facilities
Authors: Lugada Eric , Ochola Irene , Kirunda Anthony , Sembatya Moses , Mwebaze Sheila , Olowo Martin , Ladwar Denis Okidi , Komakech Henry 
Published: October 2022

Abstract
Background
Health supply chain systems are essential for effective and efficient healthcare system by ensuring availability of quality essential medicines and health supplies. While several interventions have been made to ensure the availability of quality essential medicines and health supplies, health facilities continue to report stockouts in Uganda.

Objectives
This study aimed to assess the status and performance of the supply chain system across all levels of care in health facilities in Uganda.

Methods
This was a cross-sectional study conducted in 128 public and private-not-for-profit health facilities across 48 districts in Uganda. These facilities included all levels of care from Health Centres II, III, IV, general and referral hospitals, and national referral hospitals. Data were collected using desk reviews, health facility surveys, and key informant interviews with key personnel. Stock registers were reviewed to assess the availability of a basket of essential medicines based on the essential medicines list of the Ministry of Health.

Results
Less than half (42%) of health facilities had computer hardware. Most (84%) of health facilities were using a form of Logistics Management Information System with only (6%) were using the Electronic Logistics Management Information System. Just under a third (33%) of health information officers and (51%) of public health officers’ positions were filled in the health facilities. Nearly (66%) of health facilities used supply chain data to support decision-making. Most (84%) of health facilities reported stockouts of Essential Medicines and Health Supplies in the past 6 months. The main reasons for stockouts were (59%) a sudden increase in demand (40%) delivery gaps/delayed deliveries and (35%) discrepancies in orders and deliveries. Health facilities responded to stockouts through various means including (75%) redistribution (43%) purchased from a distributor, and (30%) placing emergency orders.

Conclusions
The findings from this study show that the performance of health facilities in different supply chain processes and functions was defective. To improve the supply chain performance of health facilities, it is important to invest in infrastructure development, provide computer hardware and internet connection and strengthen the capacity key personnel. This is key for ensuring full functionality of the supply chain and availability of quality medicines and health supplies to the end-user.
Impact of Pt grain size on ferroelectric properties of zirconium hafnium oxide by chemical solution deposition
Authors: Nguyen An Hoang-Thuy , Nguyen Manh-Cuong , Nguyen Anh-Duy , Yim Ji-Yong , Kim Jeong-Han , Park No-Hwal , Jeon Seung-Joon , Kwon Daewoong , Choi Rino 
Published: October 2022

AbstractThe effects of the grain size of Pt bottom electrodes on the ferroelectricity of hafnium zirconium oxide (HZO) were studied in terms of the orthorhombic phase transformation. HZO thin films were deposited by chemical solution deposition on the Pt bottom electrodes with various grain sizes which had been deposited by direct current sputtering. All the samples were crystallized by rapid thermal annealing at 700 °C to allow a phase transformation. The crystallographic phases were determined by grazing incidence X-ray diffraction, which showed that the bottom electrode with smaller Pt grains resulted in a larger orthorhombic phase composition in the HZO film. As a result, capacitors with smaller Pt grains for the bottom electrode showed greater ferroelectric polarization. The smaller grains produced larger in-plane stress which led to more orthorhombic phase transformation and higher ferroelectric polarization.
RETRACTED ARTICLE: Mutagenesis combined with fermentation optimization to enhance gibberellic acid GA3 yield in Fusarium fujikuroi
Authors: Li Ya-Wen , Yang Cai-Ling , Peng Hui , Nie Zhi-Kui , Shi Tian-Qiong , Huang He 
Published: October 2022

AbstractGibberellic acid (GA3) is a plant growth hormone that plays an important role in the production of crops, fruits, and vegetables with a wide market share. Due to intrinsic advantages, liquid fermentation of Fusarium fujikuroi has become the sole method for industrial GA3 production, but the broader application of GA3 is hindered by low titer. In this study, we combined atmospheric and room-temperature plasma (ARTP) with ketoconazole-based screening to obtain the mutant strain 3-6-1 with high yield of GA3. Subsequently, the medium composition and fermentation parameters were systematically optimized to increase the titer of GA3, resulting in a 2.5-fold increase compared with the titer obtained under the initial conditions. Finally, considering that the strain is prone to substrate inhibition and glucose repression, a new strategy of fed-batch fermentation was adopted to increase the titer of GA3 to 575.13 mg/L, which was 13.86% higher than the control. The strategy of random mutagenesis combined with selection and fermentation optimization developed in this study provides a basis for subsequent research on the industrial production of GA3.
Graphical Abstract
Rethinking language policy and planning in the Greater Bay Area of China: insights from translanguaging theory
Authors: Wen Zhisheng , Han Lili , Hu Guangwei , Teng Mark Feng 
Published: October 2022

AbstractThis special issue sets out to revisit major bilingual and multilingual education policy and planning issues in key cities across the dynamic Greater Bay Area (GBA) of China (including Guangdong, Hong Kong, and Macau), as informed by the emerging insights from translanguaging theory (Li in Appl Linguist 39(1):9–30, 2018). Specifically, contributions are invited from the GBA and beyond to trace the milestone developments of relevant language policy and planning (LPP) initiatives featuring governmental policies on the language of instruction (e.g., English as Medium of Instruction, Chinese as Medium of Instruction) and the daily use of multiple linguistic resources or repertoires (e.g., language learner's L1 or mother tongue) in foreign/second language classrooms and/or in content-based classroom instruction. As such, major papers in the special issue not only set out to provide historical and analytical reviews of these related LPP issues across Hong Kong, Macau, and Guangdong Province but also reflect upon the language use and behaviors of the residents, showcasing their identity and attitudes and ideological stance toward the multiple languages that are being taught or used in daily life. Toward the end, we outline our research agendas for future endeavors in broader domains in the GBA and beyond through the translanguaging analytical tools. Overall, our position is that the GBA presents itself as an evolving, complex, and superdiverse zone of “Translanguaging Spaces” within which key LPP issues may need to be reconceptualized and implemented in such a way so as to fully reflect the dynamic and fluid multilingual, multicultural, and multisemiotic lived reality of the residents in this megapolis region.
Between cosmopolitanism and parochialism: return migration of early-career Israeli academics
Authors: Israel Emil , Cohen Nir 
Published: October 2022

AbstractMobile academics have traditionally been conceived as cosmopolitan subjects who favor cultural diversity and search for new professional opportunities abroad. Their return to the homeland could therefore be interpreted as a sign of parochialism, which narrows down their professional opportunities and limits their exposure to global resources. In this article, we compare returning and non-returning academics with respect to their parochial and/or cosmopolitan tendencies. Drawing on a sample of 223 Israeli Early-Career Researchers (ECRs), we examine their cosmopolitan—or otherwise parochial—propensities and assess the effect they have on their return decisions. We use statistical tests to analyze the effects of cultural orientation, attachment to the homeland-based national community, and patriotic feelings on their propensity to return. Our findings suggest that in comparison with their co-nationals who opted to remain abroad, returning ECRs exhibit higher levels of parochialism, reflected throughinter aliastronger communal dispositions and patriotic attachment as well as geographically limited job search.
Outcomes of Children With Low-Grade Gliomas in Low- and Middle-Income Countries: A Systematic Review
Authors: Ward Richard , Jones Hannah M. , Witt Davis , Boop Frederick , Bouffet Eric , Rodriguez-Galindo Carlos , Qaddoumi Ibrahim , Moreira Daniel C. 
Published: October 2022

PURPOSE Pediatric CNS tumors are increasingly a priority, particularly with the WHO designation of low-grade glioma (LGG) as one of six index childhood cancers. There are currently limited data on outcomes of pediatric patients with LGGs in low- and middle-income countries (LMICs). METHODS To better understand the outcomes of LGGs in LMICs, this systematic review interrogated nine literature databases. RESULTS The search identified 14,977 publications. Sixteen studies from 19 countries met the selection criteria and were included for data abstraction and analysis. Eleven studies (69%) were retrospective reviews from single institutions, and one (6%) captured institutional data prospectively. The studies captured a total of 957 patients with a median of 49 patients per study. Seven (44%) of the studies described the treatment modalities used. Of 373 patients for whom there was information, 173 (46%) had a gross total or near total resection, 109 (29%) had a subtotal resection, and 91 (24%) had only a biopsy performed. Seven studies, with a total of 476 patients, described the frequency of use of radiotherapy and/or chemotherapy in the cohorts: 83 of these patients received radiotherapy and 76 received chemotherapy. The 5-year overall survival ranged from 69.2% to 93.5%, although lower survival rates were reported at earlier time points. We identified limitations in the published studies with respect to the cohort sizes and methodologies. CONCLUSION The included studies reported survival rates frequently exceeding 80%, although the ultimate number of studies was limited, pointing to the paucity of studies describing the outcomes of children with LGGs in LMICs. This study underscores the need for more robust data on outcomes in pediatric LGG.
Too Close for Context
Authors: Carter Jaclyn , Clarke Michael Tavel , Halpern Faye , Mason Derritt , Nicol Jessica , Vanek Morgan 
Published: October 2022

AbstractThe activity of close reading lies at the heart of literary studies, a “signature pedagogy” that distinguishes English from other disciplines. Despite its centrality to the discipline, however, close reading has been curiously resistant to analysis. This lesson study aimed to determine where students encounter challenges in close reading. Contrary to dominant narratives in the discipline, the university students in this study were adept at formal analysis. They were challenged, on the other hand, by invitations to make intertextual and personal connections to the text. Analyzing features of successful close reading, the essay proposes that intertextual thinking and personal connection are important components. The essay recommends assessing student skills in the initial stages of teaching close reading and, when warranted, integrating instruction in intertextual thinking and making personal connections alongside formal analysis. It also suggests group discussion may help leverage these neglected components of close reading.
“We Fight Anything That Fights the Circus”: Unions and Labor Organizing under the Big Top
Authors: Ringer Andrea 
Published: October 2022

AbstractWith seasons that often stretched across continents, and a diverse and cosmopolitan group of employees, the circus was a startlingly unique mobile, transient, and global workplace. This article focuses on the significant worker activism in the circus during the late 1930s and early 1940s, particularly as it intersected with labor organizations. In 1938, nearly sixteen hundred laborers with the Ringling Brothers Circus staged a sit-in to protest unfair wages with the help of the AFL. But they were shocked when the circus responded by shutting down for the season, leaving every worker out of a job. The 1938 circus strikes were at the tail end of a long history of negotiations and disputes. These various protests, led by a global workforce of sideshow performers, canvasmen, and high-paid stars from the center ring directly led to the modernization of the circus, along with its subsequent decline. This has larger implications for understanding early globalized workforces and the historic roots of employer responses to demands of a globalized working class.
ISL1/SHH/CXCL12 signaling regulates myogenic cell migration during mouse tongue development
Authors: Zhang Wei , Yu Jiaojiao , Fu Guoquan , Li Jianying , Huang Huarong , Liu Jing , Yu Dongliang , Qiu Mengsheng , Li Feixue 
Published: October 2022

ABSTRACT
Migration of myoblasts derived from the occipital somites is essential for tongue morphogenesis. However, the molecular mechanisms of myoblast migration remain elusive. In this study, we report that deletion of Isl1 in the mouse mandibular epithelium leads to aglossia due to myoblast migration defects. Isl1 regulates the expression pattern of chemokine ligand 12 (Cxcl12) in the first branchial arch through the Shh/Wnt5a cascade. Cxcl12+ mesenchymal cells in Isl1ShhCre embryos were unable to migrate to the distal region, but instead clustered in a relatively small proximal domain of the mandible. CXCL12 serves as a bidirectional cue for myoblasts expressing its receptor CXCR4 in a concentration-dependent manner, attracting Cxcr4+ myoblast invasion at low concentrations but repelling at high concentrations. The accumulation of Cxcl12+ mesenchymal cells resulted in high local concentrations of CXCL12, which prevented Cxcr4+ myoblast invasion. Furthermore, transgenic activation of Ihh alleviated defects in tongue development and rescued myoblast migration, confirming the functional involvement of Hedgehog signaling in tongue development. In summary, this study provides the first line of genetic evidence that the ISL1/SHH/CXCL12 axis regulates myoblast migration during tongue development.
Improved Postoperative Outcomes after Prehabilitation for Colorectal Cancer Surgery in Older Patients: An Emulated Target Trial
Authors: Heil Thea C. , Verdaasdonk Emiel G. G. , Maas Huub A. A. M. , van Munster Barbara C. , Rikkert Marcel G. M. Olde , de Wilt Johannes H. W. , Melis René J. F. 
Published: October 2022

Abstract
Background
The aim of this study was to assess the effect of a multimodal prehabilitation program on perioperative outcomes in colorectal cancer patients with a higher postoperative complication risk, using an emulated target trial (ETT) design.

Patients and Methods
An ETT design including overlap weighting based on propensity score was performed. The study consisted of all patients with newly diagnosed colorectal cancer (2016–2021), in a large nonacademic training hospital, who were candidate to elective colorectal cancer surgery and had a higher risk for postoperative complications defined by: age ≥ 65 years and or American Society of Anesthesiologists score III/IV. Intention-to-treat (ITT) and per-protocol analyses were performed to evaluate the effect of prehabilitation compared with usual care on perioperative complications and length of stay (LOS).

Results
Two hundred fifty-one patients were included: 128 in the usual care group and 123 patients in the prehabilitation group. In the ITT analysis, the number needed to treat to reduce one or more complications in one person was 4.2 (95% CI 2.6–10). Compared with patients in the usual care group, patients undergoing prehabilitation had a 55% lower comprehensive complication score (95% CI −71 to −32%). There was a 33% reduction (95% CI −44 to −18%) in LOS from 7 to 5 days.

Conclusions
This study showed a clinically relevant reduction of complications and LOS after multimodal prehabilitation in patients undergoing colorectal cancer surgery with a higher postoperative complication risk. The study methodology used may serve as an example for further larger multicenter comparative effectiveness research on prehabilitation.