bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determining the correlation between pedagogical tests and the result of total distances in kayaking
Authors: Flerchuk Viktor , Antonets Vasyl , Mozolyuk Oleksandr 
Published: October 2022

The article examines the relationship between pedagogical tests and sports results at competitive distances, in kayaking. A well-grounded complex of informative pedagogical tests has been developed, which should be used to orient athletes for competitive distances of 200, 500, 1000 m, and when building a training process at the stages of preliminary and specialized basic training. For sports orientation at the stage of specialized basic training in kayaking, tests are offered that have a high probability of correlation with sports results at competitive distances. To determine the ability of rowers to sprint 200 m, experts suggest using tests characterizing power qualities, maximum power and power endurance, as well as speed capabilities. Athletes who demonstrate high speed at distances of 200 m have higher indicators of the efficiency of metabolic processes in conditions of intense work. When increasing the speed of passing tests, which determine speed capabilities, a high level of activity of anaerobic processes and the speed of deployment of functional reactions under the conditions of test loads in laboratory conditions are observed. A group of athletes specializing in the competitive distance of 500 m is characterized by a high level of anaerobic productivity, this group of athletes differs from other groups by the priority of tests in general physical training, high indicators of strength endurance, speed capabilities, speed and general endurance.
The high speed of passing the distance is associated with the manifestation of speed endurance and is mutually determined by the high efficiency of metabolic processes. At the same time, high activity of metabolic processes at a distance of 500 m and high activity of glycolysis were noted, which is confirmed by the positive correlation of indicators. For athletes specializing in the distance of 1000 m, the aerobic power of the body's systems is the leading one, and the main physical quality is endurance. Tests characterizing the aerobic power of body systems are defined as informative. Significant relationships were identified among strength endurance tests. The connection of sports results at different competitive distances with pedagogical tests, which are proposed to be used in the training activities of kayakers for their orientation to specific competitive distances, has been confirmed.
Translation of Collaborative Dementia Care Management into Different Healthcare Settings: Study Protocol for a Multicenter Implementation Trial (DCM:IMPact)
Authors: Platen Moritz , Hoffmann Wolfgang , Rädke Anika , Scharf Annelie , Mohr Wiebke , Mühlichen Franka , Michalowsky Bernhard 
Published: October 2022

Background: Collaborative care models for people living with dementia (PwD) have been developed and evaluated, demonstrating safety, efficacy, and cost-effectiveness. However, these studies are based on heterogeneous study populations and primary care settings, limiting the generalizability of the results. Therefore, this study aims to implement and evaluate collaborative care across various healthcare settings and patient populations. Objective: To describe the study design of this multicenter implementation trial. Methods: This single-arm, multicenter, longitudinal implementation study will be conducted in five different healthcare settings, including 1) physicians’ networks, 2) dementia networks, 3) counselling centers, 4) hospitals, and 5) ambulatory care services. Eligibility criteria are: having a formal dementia diagnosis or having been screened positive for dementia and living community-dwelling. The staff of each healthcare setting identifies patients, informs them about the study, and invites them to participate. Participants will receive a baseline assessment followed by collaborative individualized dementia care management, comprising proven safe, effective, and cost-effective modules. Over six months, specially-qualified nurses will assess patients’ unmet needs, transfer them to individualized care plans, and address them, cooperating with various healthcare providers. A follow-up assessment is conducted six months after baseline. Approximately 60–100 PwD per setting per year are expected to participate. Differences across settings will be assessed regarding acceptability, demand, implementation success and barriers, efficacy, and cost-effectiveness. Results: We expect that acceptability, demand, implementation success and barriers, efficacy, and cost-effectiveness will vary by patients’ sociodemographic and clinical characteristics and unmet needs in each setting. Conclusion: The results will provide evidence highlighting differences in the implementation of collaborative care in various healthcare settings and demonstrating the settings with the highest need, best conditions for a successful implementation, and highest (cost-)effectiveness, as well as the population group that benefits most from collaborative care. Trial registration: German Clinical Trials Register: DRKS00025074. Registered 16 April 2021-retrospectively registered.
Structure of the Blood Brain Barrier and the Role of Transporters in the movement of substrates across the barriers
Authors: Singh Ankul , Vellapandian Chitra 
Published: October 2022

The blood brain barrier present in brain capillaries constitutes an essential barrier mechanism for normal functioning and development of the brain of structural integrity besides neuronal function. The structure and function of the BBB are summarised besides the physical barrier formed by the endothelial tight junctions, and the transport barrier resulting from membrane transporters and vesicular mechanisms. The presence of tight junctions between adjacent endothelial cells restricts the permeability and movement of molecules between extracellular fluid and plasma. It is divided into luminal and abluminal where each solute must cross both membranes. The roles of the neurovascular unit are outlined, especially the astrocyte endfeet, pericytes, and microglia. Five different systems of facilitative transport are found in the luminal membrane and are specific for a few substrates. Nonetheless, two major facilitative carriers (System L and y+) are located in both membranes asymmetrically. In contrast, several Na+ dependent transport systems transport amino acids against its concentration gradient present in the abluminal membrane, where the sodium pump Na+/K+-ATPase is highly expressed. The trojan horse mechanism is also favoured in drug delivery by employing molecular tools to bind the drug and its formulations. In the current work, we have revised the prevailing knowledge on the cellular structure of the BBB and the transport systems present exclusively for each substrate, and the need to find transporters with modifications that facilitate the transport of various drugs. Nevertheless, the blending of the classical pharmacology with nanotechnology needs to be focussed on promising results to rule out the BBB passage for the new generation of neuroactive drugs.
High diversity and transmission dynamics of HIV-1 non-C subtypes in Bangladesh
Authors: Sarker Md. Safiullah 
Published: October 2022

BACKGROUND. Genetic diversity and molecular epidemiology of HIV are directly relevant to HIV transmission. We report here the genetic diversity and transmission dynamics of non-C subtypes of HIV-1 strains detected in Bangladeshi key populations.

RESULTS. Sequence analysis of _gag_ gene revealed four subtypes A1, B, D, G and nine CRFs (01_AE, 02_AG, 09_cpx, 10_CD, 15_AE/B, 13_cpx, 14_BG, 22_01_A1 and 25_AGU). Most of these non-C strains were detected in returnee migrant workers from different parts of the world. Phylogenetic analysis showed that the Bangladeshi HIV-1 strains detected in migrant workers and their wives and local sex workers shared common ancestries.

CONCLUSIONS. Identification of the multiple subtypes indicates high diversity of non-C HIV-1 variants circulating in Bangladesh which might have been imported by migrant workers from multiple geographical areas.
Rational control of the temperature of vortex energy separator under destabilizing influence
Authors: Kulik Anatoliy , Dergachov Kostiantyn , Pasichnik Sergiy , Sokol Dmytro 
Published: October 2022

The object of study in this article is the formation process of a rational control of the temperature of a vortex energy separator under destabilizing influences. The subject matter of the article is the process of forming a dichotomous tree by two-digit predicates from diagnostic models a vortex energy-separator device as a rational control object when destabilizing influences appear, and its further recovery. The goal is to develop an analytical approach to the formation of digital algorithms for the rational control of cold and hot air flow temperatures of a vortex energy separator. The tasks are to study the features of the process in the vortex energy-separator device; to describe a rational control system of the vortex energy-separator device; to analyze the experimental characteristics of the vortex energy-separator device; to form linear mathematical models of the nominal mode of the vortex energy-separator device; to develop linear diagnostic models that describe the inoperable states of the vortex energy separator as a rational control object; to form logical signs of diagnosing using diagnostic models, to develop recovering algorithms for the vortex energy separator. The methods used are transfer functions, discrete state space, forming production rules, two-digit predicate equations, dichotomous trees, diagnosing and recovering the operability of dynamic objects. The following results were obtained: the vortex energy-separation process features analysis, the rational control system structure and function description, the experimental characteristics analysis, the development of mathematical models, diagnostic and recovering tool development for the emergency operation process of a vortex energy separator as a rational control object for a given destabilizing influence set. Conclusions. Scientific novelty is the development of an analytical approach to the development of rational control of the vortex separation process of the air flow under the significant influence of various kinds of destabilizing influences.
Can Assembly Performance and Work Environment be Jointly Optimized? An Example Discreet Event Simulation Study
Authors: Neumann Patrick , Medbo P 
Published: October 2022

<p>We demonstrate here how discreet event simulation can be used to integrating ergonomics into design processes. In this case we test the effect of two different ways of organizing work within a conventional production line layout. We pay special attention to the sensitivity of the system to human factors such as work autonomy and reduced work pace. Results indicate the general superiority of a ‘dual-cell’ over a ‘chase-the-rabbit’ organization in accommodating human variability. The study shows how human considerations can be tested in the design process using flow simulation.</p>
<p> Keywords: Flow, Simulation, Production System Design, Psychosocial Conditions, Work Organization </p>
A Case Study of the Ergonomic Consequences of Engineering Decisions
Authors: Neumann Patrick , Kihlberg S. , Medbo P. , Winkel Jorgen 
Published: October 2022

<p>This paper presents a case study of the ergonomic consequences of engineering change. Within the context of a project to re-design an electronics assembly system a decision was made to automate transportation functions. A manual batch-cart system was changed to a line-system with automatic conveyors. </p>
The role of libraries in promoting knowledge: How to make science truly open?
Authors: Rykhtorova A. E. 
Published: October 2022

The modern open science makes an ecosystem comprising open scientific knowledge, science infrastructure, dialogue with other systems of knowledge and engaged social actors. The latter is channelized through the concept of wide social involvement in scientific research – the civil science concept. Despite the libraries are mostly oriented toward the former two components, which is due to their information functions, they are also able to build themselves in the ecosystem through collaboration with civil science project. However, such projects have not become popular, which significantly narrows down the potentialities of open science. The purpose of the article is to analyze the possibilities for libraries; entering the open science ecosystem through supporting is to open engagement of social players in science. The author discusses the obstacles on the way of the citizen science as a part open science ecosystem, and libraries involvement. Thus, underdevelopment of civil science in Russia may be partially due to insufficient dissemination of scientific thinking in the non-scientific spheres, the closeness of scientific community and its low interest in communicating with the wider audience. The analysis of 431 websites of Russian research institutes proves that just about 42 % of them popularize scientific activities. Besides, many research institute are not so eager to disseminate instructions for developing the sphere of open and citizen science. Consequently, the libraries cannot jump to the collaboration with citizen science. As the first step, the author suggests to contribute to popularization of science and scientific system and in particular, the open science, and within its context, of the citizen science oriented on the community and researchers.
Kepercayaan Merek dalam Memediasi Kesadaran Merek dengan Promosi sebagai Pendukung Minat Orang Tua Mendaftarkan Anak pada biMBA AIUEO
Authors: Syahputri Rahma Yani , Wulandari Anna 
Published: October 2022

Penelitian menganalisis kepercayaan merek dalam memediasi kesadaran merek dengan promosi sebagai pendukung minat orang tua mendaftarkan anak pada biMBA AIUEO. Penelitian dilakukan di Depok, Jawa Barat. Data penelitian diperoleh dari kuesioner yang diberikan kepada 90 responden masyarakat di Depok. Pemilihan sampel dilakukan dengan metode accidental sampling. Data hasil kuesioner dianalisis dengan Model Persamaan Struktural (SEM) diolah menggunakan software Smart PLS. Penelitian menghasilkan temuan bahwa kesadaran merek positif mempengaruhi kepercayaan merek; kepercayaan merek positif mempengaruhi minat orang tua mendaftarkan anak pada bimbingan belajar; promosi positif mempengaruhi minat mendaftarkan anak; kepercayaan merek memediasi kesadaran merek terhadap minat orang tua mendaftarkan anak di bimbingan belajar.The study analyzed brand trust in mediating brand awareness with promotion as a support for parents' interest in enrolling children in biMBA AIUEO. The study was conducted in Depok, West Java. The research data was obtained from a questionnaire given to 90 community respondents in Depok. Sample selection is carried out by the accidental sampling method. The data from the questionnaire were analyzed with a Structural Equation Model (SEM) processed using Smart PLS software. Research yielded findings that brand awareness positively affects brand trust; brand trust positively affects the interest in registering a child; positive promotion affects the interest in registering a child; brand trust mediates brand awareness of interest in enrolling children in tutoring.
Estratégias de prevenção da parada cardiorrespiratória no ambiente hospitalar
Authors: Pereira Michelly Camilo , Evangelista Brenda Pinheiro , Freitas Kerma Márcia de , Duarte Rafael Bezerra 
Published: October 2022

A Parada Cardiorrespiratória (PCR) é um evento que ocasiona a interrupção súbita da atividade cardiovascular, bem como do processo respiratório, no qual esse estágio apresenta a ausência de movimentos respiratórios, da consciência e frequência cárdica. O estudo tem por objetivo analisar por meio da literatura as estratégias utilizadas para prevenção da parada cardiorrespiratória no ambiente hospitalar. O estudo foi realizado por meio de uma revisão integrativa (RI). Nesse sentido, foram estabelecidas duas categorias temáticas na abordagem do estudo. A categoria intitulada “estratégias para a prevenção da parada cardiorrespiratória no ambiente hospitalar” apresenta medidas de prevenção para evitar essa condição clínica e reduzir a mortalidade, uma vez que a PCR na maioria das vezes é irreversível, sendo as propostas de intervenções fundamentais para a resolutividade da assistência, bem como para a promoção de agravos de em saúde. A segunda categoria intitulada “importância da equipe multiprofissional para a qualidade da assistência durante a parada cardiorrespiratória”, mostra a resolutividade do trabalho em equipe para a assistência holística. Deste modo, o estudo contribuiu para novas evidências científicas sobre a magnitude desse tema, apesar da abrangência na literatura, poucos estudos responderam o objetivo da pesquisa.
Atuação do enfermeiro na prevenção e controle do Diabetes mellitus tipo 2
Authors: Cardoso Saraí de Brito , Amorim Fernanda Cláudia Miranda , Silva Selena Maria de Sousa , Carvalho Maria Clara de Assis , Carvalho Maria Clara de Assis , Pereira Gabriele Facundo , Carvalho Cláudia Maria Sousa de , Araújo Adriana Sávia de Sousa , Montenegro João Pedro Cardoso 
Published: October 2022

Introdução: O Diabetes Mellitus, engloba um grupo de doenças metabólicas, caracterizadas por níveis elevados de glicose no sangue, devido a defeitos na secreção e/ou na ação da insulina. A atuação do Enfermeiro é imprescindível para manutenção da saúde do indivíduo, desde o monitoramento de fatores de risco, controle e atenção às complicações advindas da doença. Objetivo: Analisar as evidências científicas acerca da atuação do enfermeiro na prevenção e controle do Diabetes Mellitus tipo 2. Métodos: Trata-se de revisão integrativa, realizada a partir da identificação e análise de dados obtidos em artigos científicos, na qual foram utilizados os descritores “Diabetes Mellitus”, “Cuidados de Enfermagem”, “Prevenção de doenças” utilizando o operador booleano “and”, selecionou-se estudos publicados em português, inglês e espanhol, no período entre 2015 a 2021, nas plataformas de busca da Scientific Eletronic Library Online (SCIELO), Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) via BVS, Us National Library of Medicine National Institutes of Health (Medline-PUBMED), Web of Science, e Base de Dados em Enfermagem (BDENF). Resultados: Foram encontrados 2008 artigos, dos quais 15 atendiam critérios de inclusão e constituíram a amostra. As abordagens mais relevantes foram reconhecer a importância do cuidado de enfermagem, na prevenção e controle da Diabetes Mellitus, possíveis estratégias e intervenções inovadoras, para a promoção da saúde. Considerações finais: A assistência aos portadores de Diabetes Mellitus é complexa, requer estratégias, e o profissional Enfermeiro integra a linha de frente para educação em saúde, orientações sobre o tratamento e autocuidado, contribuindo para minimizar riscos e complicações.
Estratégias de trabalhadores no enfrentamento de doenças relacionadas ao trabalho no Sul do Brasil
Authors: Alves Luciane Maria Schmidt , Cadoná Marco André , Krug Suzane Beatriz Frantz , Alves Leonardo Schmidt , Fonseca Kelly Andressa Haas 
Published: October 2022

O estudo objetiva analisar as estratégias que os trabalhadores utilizam para a prevenção e o cuidado de doenças relacionadas às condições e ambientes de trabalho. A coleta de dados contemplou a aplicação de um formulário de pesquisa com 270 trabalhadores que residem nos municípios da Região 28 de Saúde, no Rio Grande do Sul; e, ao mesmo tempo, a realização de entrevistas com seis trabalhadoras que já vivenciaram situações de doenças relacionadas ao trabalho. Os resultados do estudo indicam, por um lado, o limitado reconhecimento das doenças relacionadas ao trabalho por parte dos trabalhadores e dos Serviços Especializados em Engenharia de Segurança e Medicina do Trabalho; e, por outro lado, as diferentes estratégias de enfrentamento, utilizadas pelos trabalhadores, diante de doenças vivenciadas e relacionadas ao trabalho. Através da análise, reafirma-se a necessidade da saúde do trabalhador ser consolidada socialmente, através do reconhecimento da centralidade do trabalho nesse processo e a importância de sua visibilidade tanto no cotidiano dos locais de trabalho, quanto na discussão de políticas públicas de saúde.
Gestação como fator de risco para complicações por SARS-CoV-2
Authors: Villafuerte Luana Kelly Marques , Blanc Sara Otoni , Oliveira Lahyse de Oliveira e , Santos Ester da Ressurreição , Blanc Luana Otoni , Vasconcelos Juliana Fraga 
Published: October 2022

Em março de 2020, a Organização Mundial da Saúde declarou pandemia pela COVID-19, com aproximadamente 192 milhões de infectados até julho de 2021. Gestantes são uma população de elevada vulnerabilidade para agravamento da doença, porquanto 27% delas apresentaram efeitos adversos, como interrupção da gravidez. Este estudo objetiva analisar os fatores que promovem susceptibilidade à infecção e agravamento pelo SARS-CoV-2 nas gestantes. Trata-se de uma revisão narrativa da literatura realizada de abril a novembro de 2021. Encontrou-se que, na gravidez, o sistema circulatório apresenta disfunção endotelial e ativação do sistema de coagulação, achado associado ao estado pró-trombótico gerado pelo SARS-CoV-2, favorecendo a ocorrência de patologias como acidente vascular cerebral. O aumento da progesterona na gestação estimula mudanças no sistema respiratório que diminuem a capacidade residual funcional e geram intolerância à hipóxia, permitindo maior susceptibilidade à infecção pelo vírus. Esse aumento hormonal altera o perfil imune Th1 e Th2, desequilíbrio encontrado também na COVID-19, contribuindo para a vulnerabilidade. Quanto às repercussões perinatais, ocorre propagação do vírus pela placenta, desencadeando uma resposta cruzada com o sistema imunológico materno, hipoperfusão placentária e outras complicações. Conclui-se que a soma dos fatores encontrados na gestante infectada pelo vírus torna-a mais vulnerável à forma grave da doença e a complicações fetais.
O novo Ensino Médio e o Projeto de Vida: mobilizando o protagonismo do aluno na escola
Authors: Sá Rafaella Coêlho , França-Carvalho Antonia Dalva , Sousa Jucyelle da Silva , Alcoforado Joaquim Luis Medeiros 
Published: October 2022

Este artigo revela uma pesquisa teórica que dialoga sobre a proposta do Projeto de Vida preconizado pela Base Nacional Comum Curricular do Ensino Médio de 2018, cuja ênfase é o protagonismo do aluno. A metodologia utilizada foi a análise bibliográfica sobre a função social da escola e da formação do aluno enquanto sujeito protagonista, dentre eles: Masschelein e Simons (2017), Goulart (2017) e Pasquali (2017). Também são abordados as Competências Socioemocionais e o Projeto de Vida para Estudantes do Ensino Médio. (Brasil, 2018). Os resultados apontam que a proposta em destaque traz como centralidade o desenvolvimento das competências socioemocionais no âmbito do currículo de forma obrigatória, na ação que denominou de Projeto de Vida para Estudantes do ensino médio, que mobiliza a escola, responsavel pela formação integral do sujeito, a redimensionar seu Projeto Político Pedagógico e seu processo educativo para incorparar ações desta natureza.