bluuebunny/crossref_metadata_2025_split huggingface dataset:
MSC-1DCNN based homogeneous slope stability state prediction method integrated with empirical information
Authors: Jia He , Zhang Sherong , Wang Chao , Wang Xiaohua , Ma Zhonggang , Tan Yaosheng 
Published: November 2022

Abstract
The mechanism of prediction of slope stability is formulated based on its material, geometrical and environmental situation, and the prediction of slope stability has been accepted as a tool for analyzing and predicting future structure stability based on geotechnical properties and failure mechanism. However, the study of slope instability is complex, which is usually difficult to be explained by mathematical methods. The number of slope cases limits the accuracy of slope stability prediction, and the soil or rock parameters of slope are variable, which poses a new challenge for prediction using traditional algorithms. To improve the accuracy of slope stability state prediction, this paper proposes an efficient slope stability state prediction method with the approach of a great robust convolutional neural network named the multi-scale multi-core one-dimensional convolutional neural network (MSC-1DCNN) and substantial Empirical information collected worldwide. Meanwhile, the collected dataset is amplified. Additionally, the probability of failure is calculated by considering the variability of soil or rock parameters. Compared with some state-of-the-art prediction methods, the MSC-1DCNN presents high prediction accuracy. Meanwhile, the proposed method is applied on a slope case, which indicates that our study provides a reliable slope stability state prediction method for homogeneity slope around the world.
Large-scale Dynamics of Radiation Driven Winds with the Re-radiation Effect
Authors: Zhu Yi 
Published: November 2022

Abstract
Note: Please see pdf for full abstract with equations.
Previous simulations studying winds only focus on the line force due to the photons from the central active galactic nucleis (AGNs). What the properties of the winds will be when including the re-radiation force due to the scattered and reprocessed photons (i.e., the re-radiation effect)? We perform simulations to study the large-scale dynamics of accretion disk winds driven by radiation line force and re-radiation force. We find that the re-radiation force drives stronger winds during the early stages. When the flows get into the steadiness, the injected winds command a decisive advantage and the re-radiation effect could be negligible. The opening angle of winds narrows as initial gas density increases. The larger the gas density is, the stronger the re-radiation effect will be. For MBH=106Mo, ε=0.3, the outflows do become much stronger with the re-radiation effect and the winds still can not escape from gravitational potential. We find that the detection probability of ultra-fast outflows (UFOs) and the properties of the winds are both consistent with the observations.
Local site effect of soil-rock ground: 1-g shaking table test
Authors: Yuan Yong , Li Siming , Yuan Haitao , Xiao Mingqing , Li Ruohan , Li Ruozhou 
Published: November 2022

Abstract
Construction sites are not generally flat but heterogeneous. It would be of significance to explore the patterns of ground response where soil and rock strata laterally distribute near the ground surface. Shaking table test of scaled free-field model was conducted to investigate the local site effect caused by the influence of soil-rock strata. In this test, model ground with artificial soil and rock was designed to reproduce the dynamic characteristics of the prototype. Recorded earthquake waves and site-specific artificial waves were selected as the bedrock motions inputted from the shaking table, in both transverse (SH wave) and longitudinal (SV wave) directions. Four sites of the ground were classified according to the combination of the soil deposit and the rock. The stranded spectral ratio (SSR) was introduced to identify the fundamental frequency and the amplification amplitude of the four sites. Correspondingly, one-dimension (1D) theoretical analysis was used to clarify the amplification effects affecting by the local constitution at each local site of the ground by comparing the response spectral ratios with the 1D analysis results (Aggravation factor). Site-specific parameters, such as the peak ground acceleration, arias intensity, and acceleration response spectra, were documented with discussions. It was found that the amplifications of locations vary with thickness of soil deposit, nonlinearity of soil property under increasing seismic intensity, and scattering of high-frequency components of input motion.
The unintended impact of environmental regulation on China’s hog sector
Authors: Zheng Xue , Yan Lingxiao , Li Dasheng , Tan Ying 
Published: November 2022

Abstract
In China, environmental regulations in relation to the hog sector are considered a key strategy for reducing pollution; however, these regulations may cause unintended effect that reduce hog production and change the distribution. In this research, we discussed the effect of abrupt campaign-style environmental regulation on the hog industry in China. Using a unique panel of national county-level hog production data, we empirically demonstrate that place-based differentiated environmental regulations lead to an unexpected decline in hog production in some regions. The implementation of central government policy varies in different regions, with restricted development areas subject to stricter environmental regulations compared to key development areas. However, such difference not only exists between provinces, but also within provinces. The results highlight the importance of formulating more refined regulation standards rather than placed-based regulation in China for future reforms, which is essential for maintaining stable production and reducing pollutions at the same time.
Subject classification codes:Q28
Disruption in SLCO5A1 gene by a balanced chromosomal translocation t(1;8)(p32.2;q13). Another evidence of the need for combined haploinsufficiency of genes SLCO5A1 and SULF1 genes as a cause of mesomelia-synostosis syndrome. Clinical and cytogenetic considerations.
Authors: Lima Ingrid Bendas Feres , de Moraes Lúcia de Fátima Marques , Fonseca Carlos Roberto da , Llerena Juan Juan Clinton , Tommerup Niels , Bastos Elenice Ferreira 
Published: November 2022

Abstract
Background: Apparently balanced translocations (ABTs) are a widely used tool for delineating candidate regions for genotype-phenotype correlation of Mendelian diseases, and with the advance of new technologies new methods are emerging to help us in this search.
Case presentation: We presente a patiente with developmental deficit associated with an apparently balanced "de novo"translocation [t(1;8)(p32.2;q13)] Chromosomal microarray analysis detected a non-pathogenic deletionin 15q12 (27,151,153-27, 173,084). Further mate-pair sequencing revealed that the breakpoint 8 is located in the region th at encompasses the SLCO5A1 gene.
Conclusions: Although the SLCO5A1 gene is disrupted by the balanced translocation, our patient does not present clinically for Mesomelia-synostosis syndrome. Our findings seek to elucidate the etiology of this disease and support the hypothesis that combined haploinsufficiency of SULF1 and SLCO5A1 is required.
A Note on Friction Velocity and Viscous Effect for Idealized Urban Canopy Flows
Authors: TIAN Geng , Wan Minping , Chen Shiyi 
Published: November 2022

Abstract
Friction velocity is one of the important scaling parameters in atmospheric boundary layer studies. However, several definitions of friction velocity exist in the literature: e.g. estimated from the total drag force or used only pressure drag, etc. In this study, a series of large-eddy simulation (LES) calculations were carried out to evaluate the impact of various definitions on the friction velocity for idealized urban geometries, i.e. staggered array of cubes with different packing densities and wind directions. We first compared the normalized velocity fields with the literature data for the case with a packing density of 25%. The results show that the LES data normalized by the friction velocity derived from the Reynolds stress using the extrinsic spatial average is more consistent with the direct numerical simulation (DNS) data. Furthermore, when varying the wind direction, the distribution of Reynolds stress and pressure drag show significant change in streamwise and spanwise directions. We further found that for packing density of 44.44%, the frictional drag accounts for more than a quarter of the total drag, and even higher than the pressure drag in parallel wind direction. This leads to the deviation of friction velocity estimated from the pressure drag and that calculated from the total drag force up to 33%. Such characteristic of viscous effect challenges the assumption widely used in wind tunnel experiments and urban canopy parameterizations that the contribution of viscous force is negligible, especially for ultra-dense arrays.
Hypoxia improves migration and limits the differentiation of rat cardiac stem cells
Authors: Sreeren Deepthi Rajendran Nair 
Published: November 2022

Abstract
The heart harbors a population of resident cardiac stem cells (CSC) that maintain tissue homeostasis. These cells also find application in cell-based therapy, where cardiac stem cells are transplanted as cardiospheres or cardiosphere-derived cells (CDCs) for myocardial regeneration. Cardiac stem cells are expanded in culture to obtain sufficient numbers for transplantation. On transplantation, cells home into the site of injury and mediate myocardial regeneration. Conventionally, cell cultures are carried out in ambient O2 (21% O2). Stem cells reside in niches where the O2 level is close to 3%. Assuming that maintenance of cells in a milieu that simulates the in-situ conditions will help in the preservation of stem cell attributes, CDCs isolated from adult Wistar rats was cultured in 3% O2 (hypoxia) and compared with CDCs maintained in 20% O2 (normoxia). Expression of c-kit and Nkx 2.5 was higher and cardiac troponin lower in hypoxia, indicating the maintenance of an undifferentiated state. Expression of von Willebrand factor and angiogenic differentiation was higher in cultures maintained in 3% O2 suggesting enhanced vasculogenic potential. Cellular senescence and intracellular reactive oxygen generation (ROS) were lower, and the proliferation rate was higher in CSCs maintained in 3% O2. Enhanced migration, proliferation, and preservation of undifferentiated state lead to the inference that, culture in low oxygen tension can increase the yield of healthy cardiac stem cells for myocardial regeneration.
Biophysical and biogeochemical effects of historical and future scenarios of anthropogenic land cover change on climate
Authors: Devaraju N , Tharammal Thejna , Bala G 
Published: November 2022

Abstract
The biophysical (land surface physical characteristics) and biogeochemical (chemical characteristics) effects of land cover change (LCC) contributed substantially to the historical climate change. Future land-use activity is expected to increase to meet the growing demand for food, fiber, and energy with uncertain sign of its effect on net climate change. Here, the relative importance of biophysical and biogeochemical effects of LCC on climate is assessed using the simulations from the Community Earth System Model (CESM1) for the historical (1850–2005) and future scenarios (Representative Concentration Pathways, RCP2.6, 4.5, and 8.5 [2006–2100]). We find that the biophysical effect of LCC in the historical period causes global mean cooling and it dampens the global mean warming due to the biogeochemical effect by ~ 38%. In the three future scenarios, the biophysical effect causes global mean warming and it is ~ 1.5 to 5-fold higher than the warming due to biogeochemical effect, depending on the RCP scenario. Increased albedo due to deforestation and the associated reduction in the absorption of shortwave radiation in temperate region during the historical period contribute dominantly to global mean biophysical cooling. In the RCP scenarios, increases in the shortwave radiation absorption and evapotranspiration in the boreal and temperate regions due to afforestation along with post-harvest regrowth contribute to strong global mean warming. Our results highlight the importance of the biophysical warming effects of LCC in the future scenarios, especially over the northern middle and high-latitude regions. Hence, this study indicate that any comprehensive assessment through land-based mitigation pathways should carefully include the biophysical effects.
Human Immunodeficiency Virus, Sexually Transmitted Infections and Tuberculosis Risk Assessments among Key Populations in Nigeria.
Authors: Usman Saheed , Arubuola Mary Anuoluwapo , Tumusiime James 
Published: November 2022

Abstract
Background

HIV key populations in Nigeria continue to face social stigma and legal implications. Homosexuality, use of any kind of drugs, and sex work remain illegal in the country. This prevents such individuals from seeking and accessing health services, resulting in an increased incidence and prevalence of HIV as well as opportunistic diseases like TB and STIs among key populations. A challenge remains, however, in determining the risk levels and prevalence of these diseases as key populations are unwilling to come forward. This study aims to carry out a risk assessment among key populations in Ondo State, Nigeria.

Methodology

Analysis was carried out to find out the risk factors among the key populations in the given sample. Various variables were first assessed against HIV, TB and STI (outcome variables) using a bivariate analysis to see which variables had a significant correlation with each of the outcome variables. After which, a multi-logistic regression analysis was carried out to identify which risk factors were significantly correlated.

Findings

Whilst the unadjusted odds ratios were reported in the results section, the main discussion was focused on adjusted odds ratios (AOR). Based on the AOR findings, men were shown to be at a higher risk of STI, HIV and TB. This is possibly due to the sample comprising of men who have sex with men, a key population with little to no access to health educations and services. Middle aged participants (36–45 year olds) had a higher risk than the younger and older age groups, due to their higher tendencies to be involved in risky sexual behaviours. Single participants were observed to have similar (in the case of HIV) or higher odds of the other outcomes in comparison to their married counterparts. There were not enough participants among separated groups to determine their odds ratio in comparison to other groups.

Conclusion

Key population groups in Nigeria continue to be at a disadvantage due to the legal restrictions imposed on them. Studies have shown that there is a slightly increased prevalence rate of HIV and STIs among PLHIV. Various factors were investigated and cross-tabulated with the diseases of interest and possible confounders were discussed.
“You need someone steering the ship for you”: Australian brain tumour care coordination needs, practices, and opportunities.
Authors: Cootes Hannah , Heinsch Milena , Wells Hannah , Tickner Campbell , Kay-Lambkin Frances 
Published: November 2022

Abstract
Objective
In Australia, care coordination has not been widely adopted in neuro-oncology services and there is a dearth of empirical evidence about routine care coordinator practices with brain tumour (BT) patients and their caregivers. In this study, we explored how neuro-oncology service models can best promote personalised, flexible interventions, and how BT care coordination can be effectively integrated within Australian health care services.

Methods
We used a qualitative approach, conducting semi-structured interviews with 21 informal brain tumour caregivers and 11 multidisciplinary health and social care professionals.

Results
Three main themes were developed: i) “No-one’s really on your team”: Need for patient-and family-centred care, partnership, and support; ii) “You need someone steering the ship for you”: Navigating complexity and guiding the whole family; and iii) “Good, shared decision-making communication improves patient outcomes every time”: Future opportunities and modifiable factors.

Conclusion
Care coordination can improve the responsiveness of BT care and increase the accessibility of already-existing services. However, many families do not have access to a central coordinating figure. Since BT care coordination is an emerging subspecialty in Australia, it is critical that neuro-oncology services review and evaluate these positions to ensure that they are adequately integrated and supported.
Will Mergers and Acquisition Vacillate the Performance of Banks? A Case Study of Public Sector Banks in India
Authors: Roopesh Roopesh , Sandhya Sandhya 
Published: November 2022

The recent change that the banking sector sees is the mergers and acquisitions occurring among the public sector banks. Merger and acquisition in the banking sector are part of the reform strategies to improve financial stability and gain smooth operational flow and synergy advantages. The research focused on the aspects of the banks' profitability, solvency, investment, and liquidity in the pre-and post-merger period. The research attempted to understand the varied reasons behind their mergers, acquisition, and success rate. The main objective was to understand the impact of synergy on the performance and profitability of banks. It was an exploratory research to understand the various objectives of mergers and to map the outcome of those objectives. The analysis was done through ratio analysis and paired t-test to gauge the impact of the pre-and post-merger scenario. The results find that the merger and acquisition are a positive move for some banks. However, there are certain banks which are coping at a slow pace with the synergy. The research also discovers that the synergy amongst the banks reacts in a varied way based on the objective of the mergers. The results indicate that the banks cope with the merger and acquisition at a varied pace due to various factors like Non-Performing Asset (NPA), debts, assets, and market share variabilities amongst the banks. The recent pandemic that the world faces can also be considered a factor for slower coping.
Gastric Cancer and Circulating microRNAs: An Updated Systematic Review and Diagnostic Meta-Analysis
Authors: Aalami Amir Hossein , Aalami Farnoosh , Sahebkar Amirhossein 
Published: November 2022

Background:Circulating microRNAs (miRNAs, miRs) are now used as noninvasive diagnostic indicators in various malignancies.Objective:Our objective is to use a meta-analysis to assess the diagnostic performance of circulating miRNAs in gastric cancer.Methods:We reviewed databases and methodically obtained papers for analysis until October 15th, 2021. The random-effect meta-analysis was performed to construct pooled diagnostic parameters. To detect the causes of heterogeneity, spearman threshold effect analysis and subgroup analysis were performed. The I2 and Chi-square tests were also used to examine the heterogeneity. The subgroup analyses were conducted based on sample types (serum/plasma/blood), normalized genes (U6, miR-16, and miR-39), qPCR mastermix (SYBR and Taqman), and country. Finally, the publication bias was estimated using Egger's funnel plot asymmetry test.Results:A total of 40 articles covering 73 studies (59 microRNAs) were included, containing 11,022 participants (6,324 cases and 4,698 controls). The overall pooled sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and area under the curve (AUC) were 0.75 (95% CI: 0.74-0.77), 0.79 (95% CI: 0.78-0.80), 4.081 (95% CI: 3.43-4.85), 0.28 (95% CI: 0.25-0.32), 16.08 (95% CI: 12.34-20.95), and 0.877 (CI: 0.84-0.90), respectively. We conducted a subgroup analysis of diagnostic values, which revealed that serum type, U6 reference gene, SYBR mastermix, and East Asian Countries (China and Japan) had better diagnostic value.Conclusion:Circulating miRs can serve as diagnostic biomarkers for gastric cancer. However, specific miRNAs still need to be discovered in diagnosing gastric cancer, especially early screening.
Influencing Factors in Tunisian Rheumatoid Arthritis Patients’ Quality of
Life: Burden and Solutions
Authors: Boussaid Soumaya , Jeriri Sarra , Rekik Sonia , Hannech Emna , Jammali Samia , Cheour Elhem , Sahli Hela , Elleuch Mohamed 
Published: November 2022

Background:
Rheumatoid Arthritis (RA) is a disease with a heavy functional, psychological, and socioeconomic impact. The management of Quality of Life (QoL) as a therapeutic objective is a fairly recent notion, especially in Tunisia. We aimed to evaluate QoL in RA patients and to identify its affecting factors.

Methods:
This was a cross-sectional study in a Tunisian rheumatology center. To assess QoL, we used the Short Form Health Survey (SF-36) and the Arthritis Impact Measurement Scales Short Form (AIMS2-SF). Health Assessment Questionnaire Disability Index (HAQ), the Hospital Anxiety and Depression Scale (HAD) for psychological disorders, Visual Analog Scale for Pain (VAS Pain), and for fatigue (VAS Fatigue) were also used. Disease activity was assessed by the Disease Activity Score (DAS28 CRP).

Results:
We enrolled 120 established RA, the mean age of our patients was 56.9±11.4 years, with a predominance of women (83.3%). The mean disease duration was 10.97±7.7 years. According to the HAD scale, 27% of our patients presented anxiety, and 26.7% had depressive disorders. There was significantly impaired QoL in patients with low educational level, dependent financial situation, long disease duration, high disease activity, high pain and fatigue levels, poor therapeutic education, functional disability, and psychological disorders (p<0.001). A strong negative correlation was detected between inflammatory markers, structural damage, and the scores of QoL. Patients under biologics scored significantly higher in the SF36 mental health domain (p<0.001).

Conclusion:
QoL is significantly poor in Tunisian RA. These patients should be managed using a multidisciplinary approach involving the patients themselves.