bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kasimovian floristic change in tropical wetlands and the Middle–Late Pennsylvanian Boundary Event
Authors: DiMichele William A. , Eble Cortland F. , Pfefferkorn Hermann W. , Elrick Scott D. , Nelson W. John , Lucas Spencer G. 
Published: November 2022

Abstract
A threshold-like vegetational change in tropical wetlands occurred in the early Kasimovian (the US Desmoinesian–Missourian boundary) – Event 3. Two earlier significant changes occurred, first in the mid-Moscovian (Atokan–Desmoinesian; ∼Bolsovian–Asturian) – Event 1, and the second in the late Moscovian (mid-Desmoinesian; mid-Asturian) – Event 2. These changes occurred during a time period of dynamic and complex physical change in Euramerican Pangaea driven by changes in polar ice volume and accompanying changes in sea level, atmospheric circulation, rainfall, and temperature. During the Event 3 change, hyperbolized as ‘the Carboniferous rainforest collapse’, lycopsid dominance of (mostly peat) swamps changed to marattialean tree-fern and medullosan pteridosperm dominance, and biodiversity decreased. Event 3 encompassed one glacial–interglacial cycle and included vegetational turnover in other wetland habitats. For several subsequent glacial–interglacial cycles peatland dominance varied, known from palynology, before stabilizing. These vegetational changes likely reflect climatic events driving unidirectional, non-reversible wetland vegetational changes, during cooler, wetter parts of glacial–interglacial cycles. Discussion is complicated by different placements of crucial stratigraphic boundaries, but under the same names, compromising both clear communication and understanding of the literature. Not the least is the floating base of the Cantabrian Substage, together with the position of the Westphalian–Stephanian Stage boundary.
Fake and Dishonest Participant Immune Secret Image Sharing
Authors: Yan Xuehu , Li Longlong , Sun Lei , Chen Jia , Wang Shudong 
Published: November 2022

Secret image sharing (SIS)
has received increased attention from the research community because of its usefulness in multiparty secure computing, access control, blockchain distributive storage and other security-oriented applications. Prevention of fake and dishonest participants is a key issue that has spurred interest in practical applications of SIS. Unfortunately, most previous SIS schemes failed to detect and locate fake or dishonest participants. In this article, an SIS for a (
k,n
)-threshold without pixel expansion is presented, which can detect and locate both fake and dishonest participants. Using a screening operation, the proposed approach fuses the benefits of polynomial-based SIS,
visual cryptographic scheme (VCS)
, and hash functions to authenticate separate participants both with and without a dealer. In addition, the proposed approach achieves lossless rebuilding of the secret image. Analyses and experiments are conducted in this study to establish the effectiveness of the presented approach.
The Adaptive Characteristics of Cholesterol and Bile Acid Metabolism in Nile Tilapia Fed a High-Fat Diet
Authors: Li Rui-Xin , Qian Yi-Fan , Zhou Wen-Hao , Wang Jun-Xian , Zhang Yan-Yu , Luo Yuan , Qiao Fang , Chen Li-Qiao , Zhang Mei-Ling , Du Zhen-Yu 
Published: November 2022

Since high-fat diet (HFD) intake elevates liver cholesterol and enhanced cholesterol-bile acid flux alleviates its lipid deposition, we assumed that the promoted cholesterol-bile acid flux is an adaptive metabolism in fish when fed an HFD. The present study investigated the characteristic of cholesterol and fatty acid metabolism in Nile tilapia (Oreochromis niloticus) after feeding an HFD (13% lipid level) for four and eight weeks. Visually healthy Nile tilapia fingerlings (average weight

3.50
±
0.05

g

) were randomly distributed into four treatments (4-week control diet or HFD and 8-week control diet or HFD). The liver lipid deposition and health statue, cholesterol/bile acid, and fatty acid metabolism were analyzed in fish after short-term and long-term HFD intake. The results showed that 4-week HFD feeding did not change serum alanine transaminase (ALT) and aspartate transferase (AST) enzyme activities, along with comparable liver malondialdehyde (MDA) content. But higher serum ALT and AST enzyme activities and liver MDA content were observed in fish fed 8-week HFD. Intriguingly, remarkably accumulated total cholesterol (mainly cholesterol ester, CE) was observed in the liver of fish fed 4-week HFD, along with slightly elevated free fatty acids (FFAs) and comparable TG contents. Further molecular analysis in the liver showed that obvious accumulation of CE and total bile acids (TBAs) in fish fed 4-week HFD was mainly attributed to the enhancement of cholesterol synthesis, esterification, and bile acid synthesis. Furthermore, the increased protein expressions of acyl-CoA oxidase 1/2 (Acox1 and Acox2), which serve as peroxisomal fatty acid β-oxidation (FAO) rate-limiting enzymes and play key roles in the transformation of cholesterol into bile acids, were found in fish after 4-week HFD intake. Notably, 8-week HFD intake remarkably elevated FFA content (about 1.7-fold increase), and unaltered TBAs were found in fish liver, accompanied by suppressed Acox2 protein level and cholesterol/bile acid synthesis. Therefore, the robust cholesterol-bile acid flux serves as an adaptive metabolism in Nile tilapia when fed a short-term HFD and is possibly via stimulating peroxisomal FAO. This finding enlightens our understanding on the adaptive characteristics of cholesterol metabolism in fish fed an HFD and provides a new possible treatment strategy against metabolic disease induced by HFD in aquatic animals.
Abriendo paso a la interpretación en lenguas indígenas: participación de una intérprete en un juicio emblemático en Perú
Authors: Sernaqué Espinoza Grecia Alexandra , Edery Ortiz Carmen Shulamit 
Published: November 2022

Las comunidades indígenas en Latinoamérica se enfrentan a situaciones de vulnerabilidad pese a que existen derechos constitucionales que los protegen y reconocen. En Perú, el proceso judicial Curva del diablo demostró los vacíos normativos del sistema judicial peruano y los diferentes desafíos que enfrenta el intérprete de lenguas indígenas en contextos judiciales. Esta investigación se enfoca en el proceso de construcción identitaria de una intérprete de lenguas indígenas para analizar las características de su participación en un juicio oral. Por ello, se estudia la trayectoria personal y profesional de la intérprete wampis Dina Ananco durante su participación en el juicio oral Curva del Diablo que procesó a ciudadanos awajún y wampis por las muertes producto del conflicto social del Baguazo. Mediante esta investigación se busca analizar el rol de Ananco como intérprete y cómo los contextos propios de su comunidad indígena y del juicio influyeron en su desarrollo personal y profesional durante y después de su participación en el juicio.
Metabolic Changes Associated With Cardiomyocyte Dedifferentiation Enable Adult Mammalian Cardiac Regeneration
Authors: Cheng Yuan-Yuan , Gregorich Zachery , Prajnamitra Ray P. , Lundy David J. , Ma Ting-Yun , Huang Yu-Hsuan , Lee Yi-Chan , Ruan Shu-Chian , Lin Jen-Hao , Lin Po-Ju , Kuo Chiung-Wen , Chen Peilin , Yan Yu-Ting , Tian Rong , Kamp Timothy J. , Hsieh Patrick C.H. 
Published: November 2022

Background:
Cardiac regeneration after injury is limited by the low proliferative capacity of adult mammalian cardiomyocytes (CMs). However, certain animals readily regenerate lost myocardium through a process involving dedifferentiation, which unlocks their proliferative capacities.

Methods:
We bred mice with inducible, CM-specific expression of the Yamanaka factors, enabling adult CM reprogramming and dedifferentiation in vivo.

Results:
Two days after induction, adult CMs presented a dedifferentiated phenotype and increased proliferation in vivo. Microarray analysis revealed that upregulation of ketogenesis was central to this process. Adeno-associated virus-driven HMGCS2 overexpression induced ketogenesis in adult CMs and recapitulated CM dedifferentiation and proliferation observed during partial reprogramming. This same phenomenon was found to occur after myocardial infarction, specifically in the border zone tissue, and HMGCS2 knockout mice showed impaired cardiac function and response to injury. Finally, we showed that exogenous HMGCS2 rescues cardiac function after ischemic injury.

Conclusions:
Our data demonstrate the importance of HMGCS2-induced ketogenesis as a means to regulate metabolic response to CM injury, thus allowing cell dedifferentiation and proliferation as a regenerative response.
Effectiveness of social support-based interventions in preventing depression in people without clinical depression: A systematic review and meta-analysis of randomized controlled trials
Authors: Campos-Paíno Henar , Moreno-Peral Patricia , Gómez-Gómez Irene , Conejo-Cerón Sonia , Galán Santiago , Reyes-Martín Sara , Bellón Juan Ángel 
Published: November 2022

Background: The evidence available on the association between social support and prevention of depression has been basically obtained from observational studies. Aim: We evaluated the effectiveness of social support-based interventions for the prevention of depression in people without clinical depression. Methods: Systematic review and meta-analysis (SR/MA) of randomized controlled trials (RCT), which were searched for in MEDLINE, EMBASE, CENTRAL, WOS, PsycINFO, OpenGrey and other sources from the inception dates to June 8, 2022. We selected RCTs that assessed the effectiveness of social support-based interventions as compared to controls, included subjects without baseline clinical depression, and measured as results a reduction in depressive symptoms and/or the incidence of new cases of depression. Pooled standardized mean differences (SMDs) were calculated from random effects models. Results: Nine RCTs involving 927 patients from North America, Asia and Europe were included. The pooled SMD was −0.43 [95% confidence interval (CI) −0.82 to −0.04; p = .031]. Sensitivity analyses confirmed the robustness of results. Heterogeneity was substantial [ I2 = 80% (95% CI: 64% to 89%)]. A meta-regression model that included usual care as comparator and the continent (Europe), explained 53% of heterogeneity. Eight RCTs had a moderate overall risk of bias and one had a high risk of bias. Follow-up was ⩾1 year in only three RCTs. There was no statistical evidence of publication bias. The quality of evidence, as measured on GRADE guidelines, was low. Conclusion: Social support-based interventions had a small preventive effect on depression. Longer RCTs with a low risk of bias are necessary.
Perception of Coronavirus in Children Through the Interpretation of Metaphors
Authors: Ayyıldız Tülay Kuzlu , Akkoç Betül , Kurt Aylin 
Published: November 2022

The purpose of this study is to determine the perception of coronavirus in children between the ages of 7-18 through the interpretation of metaphors. This qualitative study was conducted with a total of 34 children between the ages of 7-18 years The metaphors obtained from the content analysis were categorized into two main themes and sub-themes. The main themes were categorized as barrier at COVID-19 and fear at coronavirus as fear. The most striking metaphors in the study, such as death, deadly, disease, scary, germ, snake venom, black hole, darkness, gun, lead, were the metaphors in the “Deadly” category, which were revealed by children. In unexpected situations, it is beneficial for parents and health care professionals to establish clear, open, and reassuring communication with their children.
Aortic tissue pathology in reoperative post-dissection repair following prior use of BioGlue
Authors: Pacini Davide , Murana Giacomo , Di Marco Luca , Costantino Antonino , Votano Daniela , Ray Gregory 
Published: November 2022

Aim The benefits of BioGlue as a surgical adjunct in aortic procedures have been demonstrated in several studies, but limited information is available regarding the associated histopathological findings of aortic tissue at the time of reoperation. The objective of this study was to assess, at reoperation, the histopathological characteristics of aortic tissue which has had BioGlue applied during a previous surgery. Methods This prospective, single-center, single-arm study enrolled patients who were undergoing aortic reoperation and who had BioGlue used during previous aortic surgery. Histopathological assessment of aortic specimens obtained intraoperatively was performed on tissue that would have been removed independent of subject participation in the study. Results A total of 11 patients were enrolled and based on gross assessment, excessive amounts of BioGlue had been applied during the initial surgery in 36.4% of cases. The samples with the greatest amount of residual BioGlue demonstrated moderate to marked inflammatory responses, while the remaining samples demonstrated minimal to moderate inflammatory responses. Calcification of residual BioGlue was noted in 4 cases. Substantial medial degeneration was associated with suture line dehiscence in 4 cases, some of which had a large quantity of residual BioGlue. No evidence of suture degradation was observed. Conclusions Cases with surgical anastomosis dehiscence were associated with substantial medial degeneration. While no histologic findings directly linked BioGlue to these degenerative changes, a contributory role cannot be excluded. Following the manufacturer's instructions for appropriate application of BioGlue is crucial to prevent potential complications.
Tradeoffs, Constraints, and Strategies in Transgender and Nonbinary Young Adults’ Romantic Relationships: The Identity Needs in Relationships Framework
Authors: Murchison Gabriel R. , Eiduson Rose , Agénor Madina , Gordon Allegra R. 
Published: November 2022

Prior research suggests that prejudice and structural disadvantage (e.g., cissexism, racism, sexism) put transgender and nonbinary (TNB) young adults at risk for adverse romantic relationship experiences, yet supportive romantic relationships may help TNB young adults cope with these stressors and promote their psychological wellbeing. Accordingly, there is a need to better understand how TNB young adults navigate romantic relationships in the context of prejudice and structural disadvantage. To address this topic, we analyzed in-depth interviews with TNB young adults (18–30 years; N = 30) using template-style thematic analysis, guided by intersectionality as an analytical framework. Our analysis resulted in three themes. Theme 1 describes how prejudice and structural disadvantage constrained the strategies that TNB young adults used to pursue fulfilling romantic relationships (e.g., leaving adverse relationships). Theme 2 addresses the tradeoffs that some participants faced in their romantic relationships, including tradeoffs between psychological needs related to their social identities (e.g., gender identity affirmation) and general psychological needs (e.g., intimacy). Theme 3 highlights individual and contextual factors (e.g., lessons from prior romantic relationships) that helped participants build fulfilling romantic relationship. These themes form the basis for the Identity Needs in Relationships Framework, a new conceptual framework addressing how TNB young adults navigate romantic relationships in the context of prejudice and structural disadvantage. The framework offers an explanation for why some TNB young adults maintain romantic relationships that seem to undermine their wellbeing, and it draws attention to strategies and resources that may help TNB young adults form fulfilling romantic relationships despite the prejudice and structural disadvantage they face.
Superannuation fees, asset allocation and fund performance
Authors: Ainsworth Andrew , Akhtar Shumi , Corbett Adam , Lee Adrian , Walter Terry 
Published: November 2022

Superannuation fees have come under public scrutiny in recent years with the belief they are too high. We examine the determinants of fees and their relationship with fund performance. Superannuation funds with higher investment fees have higher allocations to asset classes that trade in more complex markets. For-profit retail funds charge both higher investment and administration fees than other funds. Funds with higher investment fees do not generate higher returns than the least expensive funds. These findings suggest that superannuation members may not earn higher after-fee risk-adjusted returns by holding funds with higher fees. JEL Classification: G11
One-layer macroscopic verus two-layer microscopic vasovasostomy: Our experience in two referral hospitals
Authors: Amjadi Mohsen , Jahantabi Elham , Nouri Hedayatolah , Nourizadeh Davoud , AsrBadr Yadollah Ahmadi , Salehi-Pourmehr Hanieh 
Published: November 2022

Objective: Vasovasostomy is the most common surgery to restore the fertility of vasectomized men. This study aimed to compare the outcomes of one-layer macroscopic VV (MOLVV) or two-layer microscopic VV (TLMVV) Methods: This study was performed on the medical records of 100 patients who underwent VV surgery in two tertiary hospitals from 2014 to 2017. All patient information, including demographic and sperm analysis, was collected. The chi-square test, independent t-test, and survival analysis using Kaplan–Meyer test and Cox regression were performed to analyze the data using SPSS software version 25, and the significance level was considered 0.05. Results: The fertility rate in patients of both groups was 15%. The findings showed a statistically significant difference between the mean percentage of normal sperm morphology according to the type of surgery ( p = 0.045). There was no statistically significant difference between the mean sperm count, sperm motility percentage, and mean hospital costs according to the type of surgical procedure ( p > 0.05). The incidence of spouse pregnancy in the TLMVV method after 15 and 24 months was 87.5% and 58.3%, respectively. In patients with unilateral anastomosis, the incidence of pregnancy at 13 and 15 months after surgery was 98.7% and 95.8%, respectively. The mean and median time of pregnancy in the spouses of patients with each surgical shower were 24 and 25 months. Other variables had no significant effect on spouse pregnancy. Conclusion: Vasovasostomy with the one and two-layer methods had equal results. The number, movement, and normal morphology of sperm after surgery were low. Therefore, these people will need assisted reproductive techniques.
Personal digital technology use among practicing Registered Nurses and Registered Practical Nurses
Authors: Donelle Lorie , Hiebert Brad , Hall Jodi , Ledoux Kathleen , Ashfield Sarah 
Published: November 2022

Many clinicians are using their personal digital devices (such as smartphones) while at work for personal and professional purposes. The purpose of this research was to understand how Ontario nurses used their own digital devices within the workplace. Reported here are the findings from the on-line questionnaire of a mixed methods design. Participants (N = 169) had a mean age of 41 years, were mostly female, and with an average of 15.2 years of nursing experience. Most (73%) used their own device within the workplace for pragmatic reasons (telling time), patient care (accessing information, drug management, and administration), and communication among the healthcare team. This research offers emerging insight into how personally owned devices are being integrated into healthcare practices and highlighted tensions among workplace efficiency and enhanced team communication. This research supports the development of guidelines for personal device use within healthcare settings.
Quantitative Assessment of Computed Tomography Energy Use and Cost Savings Through Overnight and Weekend Power Down in a Radiology Department
Authors: Brown Maura , Snelling Eric , De Alba Moises , Ebrahimi Ghazal , Forster Bruce B. 
Published: November 2022

Purpose: To assess energy and cost savings when a CT scanner is powered down during overnight non-operational times compared with the CT scanner left on full power or partial shutdown mode. Materials and Methods: Temporary portable power data loggers were placed on the power supply to the CT scanner to measure the energy consumption of the CT scanner in 3 power modes over 9 weeks: system ON (computer on, gantry on), computer ON (computer on/gantry off), and system shutdown (computer off/gantry off). Energy was separated into daily average consumption during normal operating hours and consumption after hours for three different day types: weekdays, Saturdays, and Sundays/Holidays. To estimate savings, the average after hours energy use per day during the system ON was compared to each of the two power saving modes. 95% confidence intervals were calculated for each mode and savings result. Results: Overnight and Sunday system shutdown compared to system ON mode is shown to save approximately 14 000 kWh over one year with a 95% confidence interval of (13 899 kWh, 14 464 kWh) as calculated by the electricity provider. Conclusion: Energy consumed by a CT scanner can be significantly reduced through system shutdown when the unit is non-operational, saving emissions and cost. In addition to cost and energy savings, this study emphasizes the importance of clinician leadership in convening interdisciplinary teams outside of usual healthcare silos to rethink how we purposefully use energy and reduce waste.
Blood Biomarkers for the Diagnosis of Neurodegenerative Dementia: A Systematic Review
Authors: Santos Filipa , Cabreira Verónica , Rocha Sara , Massano João 
Published: November 2022

Importance Accurately diagnosing neurodegenerative dementia is often challenging due to overlapping clinical features. Disease specific biomarkers could enhance diagnostic accuracy. However, CSF analysis procedures and advanced imaging modalities are either invasive or high-priced, and routinely unavailable. Easily accessible disease biomarkers would be of utmost value for accurate differential diagnosis of dementia subtypes. Objective To assess the diagnostic accuracy of blood-based biomarkers for the differential diagnosis of AD from Frontotemporal Lobar Degeneration (FTLD), or AD from Dementia with Lewy Bodies (DLB). Methods Systematic review. Three databases (PubMed, Scopus, and Web of Science) were searched. Studies assessing blood-based biomarkers levels in AD versus FTLD, or AD versus DLB, and its diagnostic accuracy, were selected. When the same biomarker was assessed in three or more studies, a meta-analysis was performed. QUADAS-2 criteria were used for quality assessment. Results Twenty studies were included in this analysis. Collectively, 905 AD patients were compared to 1262 FTLD patients, and 209 AD patients were compared to 246 DLB patients. Regarding biomarkers for AD versus FTLD, excellent discriminative accuracy (AUC >0.9) was found for p-tau181, p-tau217, synaptophysin, synaptopodin, GAP43 and calmodulin. Other biomarkers also demonstrated good accuracy (AUC = 0.8-0.9). For AD versus DLB distinction, only miR-21-5p and miR-451a achieved excellent accuracy (AUC >0.9). Conclusion Encouraging results were found for several biomarkers, alone or in combination. Prospective longitudinal designs and consensual protocols, comprising larger cohorts and homogeneous testing modalities across centres, are essential to validate the clinical value of blood biomarkers for the precise etiological diagnosis of dementia.