bluuebunny/crossref_metadata_2025_split huggingface dataset:
Brief composite mobility index predicts post-stroke fallers after hospital discharge
Authors: Plummer Prudence , Feld Jody A. , Mercer Vicki S. , Ni Pengsheng 
Published: October 2022

IntroductionCommunity-dwelling, ambulatory stroke survivors fall at very high rates in the first 3–6 months. Current inpatient clinical assessments for fall risk have inadequate predictive accuracy. We found that a pre-discharge obstacle-crossing test has excellent specificity (83%) but lacks acceptable sensitivity (67%) for identifying would-be fallers and non-fallers post discharge.HypothesisWe assessed the hypothesis that combining the obstacle-crossing test with other highly discriminatory fall risk factors would compensate for the obstacle test’s fair sensitivity and yield an instrument with superior prediction accuracy.Methods45 ambulatory stroke survivors (60 ± 11 years old, 15 ± 11 days post stroke) being discharged home completed a battery of physical performance-based and self-reported measures 1–5 days prior to discharge. After discharge, participants were prospectively followed and classified as fallers (≥1 fall) or non-fallers at 3 months. Pre-discharge measures with the largest effect sizes for differentiating fallers and non-fallers were combined into a composite index. Several variations of the composite index were examined to optimize accuracy.ResultsA 4-item discharge composite index significantly predicted fall status at 3-months. The goodness of fit of the regression model was significantly better than the obstacle-crossing test alone, χ2(1) = 6.036, p = 0.014. Furthermore, whereas the obstacle-crossing test had acceptable overall accuracy (AUC 0.78, 95% CI, 0.60–0.90), the composite index had excellent accuracy (AUC 0.85, 95% CI, 0.74–0.96). Combining the obstacle-crossing test with only the step test produced a model of equivalent accuracy (AUC 0.85, 95% CI, 0.73–0.96) and with better symmetry between sensitivity and specificity (0.71, 0.83) than the 4-item composite index (0.86, 0.67). This 2-item index was validated in an independent sample of n = 30 and with bootstrapping 1,000 samples from the pooled cohorts. The 4-item index was internally validated with bootstrapping 1,000 samples from the derivation cohort plus n = 9 additional participants.ConclusionThis study provides convincing proof-of-concept that strategic aggregation of performance-based and self-reported mobility measures, including a novel and demanding obstacle-crossing test, can predict post-discharge fallers with excellent accuracy. Further instrument development is warranted to construct a brief aggregate tool that will be pragmatic for inpatient use and improve identification of future post-stroke fallers before the first fall.
Combining targeted and systematic prostate biopsy improves prostate cancer detection and correlation with the whole mount histopathology in biopsy naïve and previous negative biopsy patients
Authors: Mischinger Johannes , Schöllnast Helmut , Zurl Hanna , Geyer Mark , Fischereder Katja , Adelsmayr Gabriel , Igrec Jasminka , Fritz Gerald , Merdzo-Hörmann Martina , Elstner Jörg , Schmid Johannes , Triebl Alfred , Trimmel Viktoria , Reiter Clemens , Steiner Jakob , Rosenlechner Dominik , Seles Maximilian , Pichler Georg P. , Pichler Martin , Riedl Jakob , Schöpfer-Schwab Stephanie , Strobl Jakob , Hutterer Georg C. , Zigeuner Richard , Pummer Karl , Augustin Herbert , Ahyai Sascha , Mannweiler Sebastian , Fuchsjäger Michael , Talakic Emina 
Published: October 2022

ObjectiveGuidelines for previous negative biopsy (PNB) cohorts with a suspicion of prostate cancer (PCa) after positive multiparametric (mp) magnetic-resonance-imaging (MRI) often favour the fusion-guided targeted prostate-biopsy (TB) only approach for Prostate Imaging-Reporting and Data System (PI-RADS) ≥3 lesions. However, recommendations lack direct biopsy performance comparison within biopsy naïve (BN) vs. PNB patients and its prognostication of the whole mount pathology report (WMPR), respectively. We suppose, that the combination of TB and concomitant TRUS-systematic biopsy (SB) improves the PCa detection rate of PI-RADS 2, 3, 4 or 5 lesions and the International Society of Urological Pathology (ISUP)-grade predictability of the WMPR in BN- and PNB patients.MethodsPatients with suspicious mpMRI, elevated prostate-specific-antigen and/or abnormal digital rectal examination were included. All PI-RADS reports were intramurally reviewed for biopsy planning. We compared the PI-RADS score substratified TB, SB or combined approach (TB/SB) associated BN- and PNB-PCa detection rate. Furthermore, we assessed the ISUP-grade variability between biopsy cores and the WMPR.ResultsAccording to BN (n = 499) vs. PNB (n = 314) patients, clinically significant (cs) PCa was detected more frequently by the TB/SB approach (62 vs. 43%) than with the TB (54 vs. 34%) or SB (57 vs. 34%) (all p &lt; 0.0001) alone. Furthermore, we observed that the TB/SB strategy detects a significantly higher number of csPCa within PI-RADS 3, 4 or 5 reports, both in BN and PNB men. In contrast, applied biopsy techniques were equally effective to detect csPCa within PI-RADS 2 lesions. In case of csPCa diagnosis the TB approach was more often false-negative in PNB patients (BN 11% vs. PNB 19%; p = 0.02). The TB/SB technique showed in general significantly less upgrading, whereas a higher agreement was only observed for the total and BN patient cohort.ConclusionDespite csPCa is more frequently found in BN patients, the TB/SB method always detected a significantly higher number of csPCa within PI-RADS 3, 4 or 5 reports of our BN and PNB group. The TB/SB strategy predicts the ISUP-grade best in the total and BN cohort and in general shows the lowest upgrading rates, emphasizing its value not only in BN but also PNB patients.
Surgical and short-term outcomes in robotic and laparoscopic distal gastrectomy for gastric cancer with enhanced recovery after surgery protocol: A propensity score matching analysis
Authors: Huang Weijia , Liu Siyu , Chen Junqiang 
Published: October 2022

ObjectiveThis study aims to evaluate the short-term surgical outcomes of laparoscopy-assisted distal gastrectomy (LADG) and robot-assisted distal gastrectomy (RADG) for gastric cancer (GC) with enhanced recovery after surgery (ERAS) protocols.MethodsWe reviewed the medical records of 202 patients undergoing radical distal gastrectomy; among them, 67 cases were assisted through RADG, while 135 cases were assisted through LADG along with ERAS. We retrospectively collected the medical records in succession from a database (January 2016–March 2019). We adopted propensity score matching to compare surgical and short-term outcomes of both groups.ResultsAfter the successful examination of 134 cases, including 67 receiving RADG and 67 undergoing LADG, the operative times were noted as 5.78 ± 0.96 h for the RADG group and 4.47 ± 1.01 h for the LADG group (P &lt; 0.001). The blood loss was noted as 125.52 ± 101.18 ml in the RADG group and 164.93 ± 109.32 ml in the LADG group (P &lt; 0.05). The shorter time to first flatus was 38.82 ± 10.56 h in the RADG group and 42.88 ± 11.25 h in the LADG group (P &lt; 0.05). In contrast, shorter days of postoperative hospital stay were 5.94 ± 1.89 days in the RADG group and 6.64 ± 1.92 days in the LADG group (P &lt; 0.05). Also, the RADG group (84483.03 ± 9487.37) was much more costly than the LADG group (65258.13 ± 8928.33) (P &lt; 0.001). The postoperative overall complication rates, numbers of dissected lymph nodes, visual analogue scale (VAS), and time to start a liquid diet for the RADG group and the LADG group were similar.ConclusionsIn this research, we concluded that RADG provides surgical benefits and short-term outcomes compared to LADG for GC with ERAS.
Diagnostic challenges and treatment options in patients with solitary fibrous tumor: A single-center observational study
Authors: Ozaniak Andrej , Hladik Pavel , Lischke Robert , Strizova Zuzana 
Published: October 2022

IntroductionSolitary fibrous tumor (SFT) is an extremely rare disease with a high misdiagnosis rate and a potentially malignant biologic nature. We have collected and analyzed data from 18 SFT patients to provide a deeper insight into this uncommon disease entity.MethodsIn our study, 18 patients who had undergone surgery between April 2014 and December 2021 for the diagnosis of SFT were evaluated. The collected data for each patient included the location of the SFT, the preoperative diagnosis, the definitive histological diagnosis, the presence of postoperative complications, the time of recurrence, the time of systemic progression, the type of treatment, and the survival rate. The median follow-up was 36 months.ResultsIn three patients, the preoperative diagnosis did not correlate with the definitive histology of SFT. In patients with the limb location of SFT, no signs of recurrence nor distant metastases were seen within the study period. In total, 50% of the postsurgical complications were associated with the abdominal location of the SFT. In newly diagnosed SFT patients, two patients (20%) developed local recurrence, and the median time until recurrence was 22.5 months. Out of patients that were admitted and operated on for recurrent SFT, 67% relapsed, and the median time to relapse was 9.5 months. The systemic progression of the disease was observed in 33% of patients treated for recurrent SFT.ConclusionIn our study, the misdiagnosis rate was high and correlated with previously published studies. Postsurgical complications were associated with the extrathoracic location of SFT. The mainstay of SFT treatment remains radical surgery, although radiotherapy alone can significantly improve overall survival. Clinical trials are urgently needed to evaluate the potential effect of other treatment modalities, such as immunotherapy and targeted therapy, in SFT patients.
Experimental infection of high health pigs with porcine circovirus type 2 (PCV2) and Lawsonia intracellularis
Authors: Hansen Mette S. , Jensen Tim K. , Hjulsager Charlotte K. , Angen Øystein , Riber Ulla , Nielsen Jens , Heegaard Peter M. H. , Larsen Lars E. 
Published: October 2022

BackgroundPorcine circovirus type 2 (PCV2) and Lawsonia intracellularis infections can cause enteritis in pigs. A Danish study showed a significantly higher probability of detecting PCV2 without concurrent L. intracellularis infection, indicating that one of these pathogens has an impact on the dynamics of the other. Therefore, a delayed co-infection model was set up, initially aiming at investigating the interaction between PCV2 and L. intracellularis in pigs challenged with PCV2 and 2 weeks later with L. intracellularis. But due to PCV2 contamination of the L. intracellularis inoculum the aim was revisited to describing the infection dynamics and pathogenesis of pigs infected with PCV2 followed by delayed simultaneous exposure to PCV2 and L. intracellularis. Twenty-four high-health piglets were divided into three groups of eight pigs (A, B, C) and inoculated at experimental day (EXD) 0 with mock (groups A and B) or PCV2 (group C), and at EXD 14 with mock (group A) or L. intracellularis/PCV2 (groups B and C). The pigs underwent daily clinical examination, and were necropsied at EXD 51–52. Furthermore, histology, immunohistochemistry, serology and PCR for PCV2 and L. intracellularis, and measurement of C-reactive protein were carried out.ResultsGroup A remained negative for PCV2 and L. intracellularis. Following inoculation with L. intracellularis/PCV2, no significant differences were observed between group B and C, however pigs already infected with PCV2 (group C) showed milder clinical signs and exhibited milder intestinal lesions, less shedding of L. intracellularis and developed higher L. intracellularis antibody titers than the pigs in group B that only received the combined infection. Though the differences between group B and C were non-significant, all results pointed in the same direction, indicating that the pigs in group B were more affected by the L. intracellularis infection compared to the pigs in group C.ConclusionsPrevious exposure to PCV2 had limited impact on the subsequent exposure to a combined L. intracellularis/PCV2 inoculation. However, there was a tendency that the infection dynamics of PCV2 and development of antibodies to PCV2 and L. intracellularis were altered in pigs previously exposed to PCV2. These differences should be confirmed in further experimental trials.
Factores que inciden en la calificación que los docentes asignan a los alumnos
Authors: Pérez García José , López Ortega María de los Ángeles 
Published: October 2022

El propósito de este artículo fue determinar las prácticas de evaluación que sustentan la calificación asignada por los profesores a los alumnos y que tan válida y confiable es la información que sustenta la calificación. Se utilizó como metodología el análisis documental para identificar la literatura especializada sobre los factores que influyen en la calificación que los profesores asignan a los alumnos. Se analizaron 27 estudios y se encontró predominio de prácticas no alineadas a los programas de estudio, calificaciones basadas en una mezcla de factores cognitivos y no cognitivos y ausencia de formación en evaluación. Se concluye que es cuestionable la confiabilidad y validez de las calificaciones asignadas por los profesores, es necesario fortalecer la literacidad en evaluación de los docentes y directivos escolares, entrenamiento en prácticas de calificación efectivas y promover la evaluación formativa.
Efektivitas Blended Learning Pada Mata Kuliah Bahasa Indonesia
Authors: Budiantoro Tekad , Karolina  
Published: October 2022

Tujuan dari penelitian ini adalah mendeskripsikan efektivitas penerapan blended learning pada mata kuliah Bahasa Indonesia untuk meningkatkan hasil belajar mahasiswa. Penelitian ini merupakan penelitian deskriptif kuantitatif yang dilakukan pada semester genap 2020/2021. Subyek penelitian adalah 50 orang mahasiswa Prodi Akuntansi. Data dikumpulkan dari tes hasil belajar mahasiswa. Data dianalisis dengan 3 cara yakni, (1) menganalisis secara deskriptif dari hasil rata-rata tes hasil belajar, (2) menganalisis dengan menggunakan uji-t berpasangan untuk mendeskripsikan signifikan atau tidak nya perbedaan hasil pretest dan posttest, (3) menganalisis dengan uji n-gain untuk mengetahui level efektivitasnya dalam meningkatkan hasil belajar mahasiswa. Hasil penelitian menunjukkan bahwa, rerata pretest adalah 13,56 dan rerata posttest adalah 77,14. Hasil sig 2 tailed dari uji-t berpasangan lebih kecil dari 0.05 sehingga ada perbedaan yang signifikan antara pretest dan posttest. N-gain score adalah 0,74 yang berarti efektivitasnya memiliki kategori tinggi. Dengan demikian, disimpulkan bahwa penerapan blended learning pada mata kuliah Bahasa Indonesia efektif dalam meningkatkan hasil belajar mahasiswa dengan kategori tinggi.
Tingkat Terkendali Bahasa Indonesia pada Media Luar Ruang di Kota Kendari
Authors: Karim Karim , Mando La , Iye Risman 
Published: October 2022

Penelitian ini bertujuan menganalisisis pemakaian bahasa Indonesia pada media luar ruang berdasarkan aspek fisik, bahasa, serta mengetahui peringkat keterkendalian pemakaian bahasa Indonesiapada media luar ruang di Kota Kendari. Penelitian ini merupakan penelitian kualitatif . Populasi penelitian ini adalah seluruh media luar ruang yang berada di Kota Kendari. Adapun sampel berjumlah 70 (tujuh puluh) foto media luar ruang dari empat lembaga pemerintah (28 foto), empat lembaga pendidikan (28 foto), dua lembaga swasta (14 foto). Langkah pengumpulan data, yaitu: (a) mengumpulkan data penggunaan bahasa di ruang publik di Kota Kendari, (b) memilih tujuh puluh data yang mewakili tujuh objek pengutamaan bahasa Indonesia. Hasil penelitian menunjukan (1) penggunaan bahasa meliputi penempatan bahasa Indonesiadan bahasa asing; dan (2) kesalahan kaidah kebahasaan terjadi pada tataran ejaan dan pilihan kata.Penggunaan Bahasa Indonesiapada media luar ruang di Kota Kendar menunjukkan wilayah yang penggunaan bahasa di ruang publiknya kurang terkendali: secara fisik terdapat bahasa campuran yaitu Bahasa Indonesiadan bahasa asing; kaidah kebahasaan baik pada struktur namun masih terdapat kesalahan pada tataran ejaan dan pilihan kata; dan tipografi kebahasaan mulai lebih baik.
Temperature sensing based on multimode interference in polymer optical fibers: sensitivity enhancement by PC-APC connections
Authors: Wang Kun , Mizuno Yosuke , Kishizawa Kazuya , Toyoda Yuma , Lee Heeyoung , Ichige Koichi , Kurz Wolfgang , Dong Xingchen , Jakobi Martin , Koch Alexander W. 
Published: October 2022

Abstract
A simple, stable, and high-sensitivity temperature sensor based on multimode interference in a polymer optical fiber (POF) with higher-order mode excitation has been developed. In a single-mode–multimode–single-mode (SMS) structure, one end of the multimode POF with physical-contact (PC) connectors is connected to a silica single-mode fiber with an angled-PC (APC) connector. We compare the temperature sensing characteristics of the three configurations (no PC-APC, PC-APC at input, and PC-APC at output) and obtain the highest temperature sensitivity of 219.2 pm °C−1, which is more than double the value of the standard (no PC-APC) SMS structure.
Penerimaan Diri Ibu dengan Anak Berkebutuhan Khusus di Sekolah Luar Biasa (SLB) Muhammadiyah Sumedang 2018
Authors: Yulianti Mona 
Published: October 2022

Anak Berkebutuhan Khusus (ABK) merupakan kelainan motorik yang banyak ditemukan pada anak-anak dan kejadiannya semakin tinggi setiap tahunnya. Di Indonesia, jumlah anak usia sekolah, yaitu 5 - 14 tahun, ada sebanyak 42,8 juta jiwa. Jika mengikuti perkiraan tersebut, maka diperkirakan ada kurang lebih 4,2 juta anak Indonesia yang berkebutuhan khusus. Pada umunya mempunyai anak berkebutuhan khusus membebani secara fisik, mental sosial, dan ekonomi. Tujuan dari penelitian ini adalah untuk mengekplorasi secara mendalam penerimaan diri ibu dengan anak berkebutuhan khusus. Metode penilitian menggunakan menggunakan penelitian kualitatif dengan pendekatan fenomenologi. Partisipan dalam penelitian ini sebanyak 3 orang ibu yang mempunyai anak berkebutuhan khusus yang diambil dengan menggunakan metode criterion sampling di pilih oleh peneliti. Data dianalisa dengan menerapkan teknik Collaizi. Tema yang teridentifikasi terkait penerimaan diri ibu dengan anak berkebutuhan khusus berjumlah 7 tema, yaitu 1) Persepsi ibu tentang penyebab anak berkebutuhan khusus, 2) upaya mencari pertolongan terhadap masalah anak berkebutuhan khusus, 3) perkembangan kesehatan anak berkebutuhan khusus, 4) Perilaku Adaptif ibu selama merawat anak berkebutuhan khusus, 5) Bentuk dan sumber dukungan yang diperoleh ibu selama merawat anak berkebutuhan khusus, 6) bentuk dan sumber hambatan yang di temui ibu selama merawat anak berkebutuhan khusus, 7) Penerimaan diri ibu memiliki anak berkebutuhan khusus. Penelitian ini diharapkan dapat meningkatkan wawasan dan keterampilan perawat anak dalam memberikan dukungan bagi Ibu yang mempunyai anak berkebutuhan khusus (ABK)
Model Generalizability Investigation for GFCE-MRI Synthesis in Radiotherapy of NPC patients Using Multi-institutional Data and Patient-based Data Normalization
Authors: Li Wen , Lam Saikit , Li Tian , Kleesiek Jens , Cheung Andy Lai-Yin , Sun Ying , Lee Francis Kar-ho , Au Kwok-hung , Lee Victor Ho Fun , Cai Jing 
Published: October 2022

<p>In this study, we aimed at investigating generalizability of GFCE-MRI model using data from seven institutions by manipulating heterogeneity of training MRI data under two popular normalization approaches. A multimodality-guided synergistic neural network (MMgSN-Net) was applied to map from T1-weighted and T2-weighted MRI to contrast-enhanced MRI (CE-MRI) for GFCE-MRI synthesis in patients with nasopharyngeal carcinoma. MRI data from three institutions were used separately to generate three uni-institution models and jointly for a tri-institution model. Min-Max and Z-Score were applied for data normalization of each model. MRI data from the remaining four institutions served as external cohorts for model generalizability assessment. Quality of GFCE-MRI was quantitatively evaluated against ground-truth CE-MRI using mean absolute error (MAE) and peak signal-to-noise ratio (PSNR). Results showed that performance of all uni-institution models remarkably dropped on the external cohorts. By contrast, model trained using multi-institutional data with Z-Score normalization yielded significantly improved model generalizability </p>
أثر العمل عن بعد على كفاءة الأداء الوظيفي في ظل أزمة كورونا: (بالتطبيق على مكتب وزير الدولة بمحافظة ظفار ووزارة العمل وبلدية ظفار بسلطنة عمان )
Authors: بلال زروق 
Published: October 2022

تهدف هذه الدراسة إلى تحديد أثر العمل عن بعد في كفاءة الأداء الوظيفي في ظل أزمة كرونا في القطاع الحكومي بمحافظة ظفار في سلطنة عمان. تكونت عينة الدراسة من 180 موظفاً بمكتب وزير الدولة بمحافظة ظفار، وزارة العمل وبلدية ظفار. ولتحقيق أهداف الدراسة، اعتمد البحث على المنهج الوصفي والتحليلي وتم الاعتماد على الاستبيان كأدأة لجمع البيانات. توصلت الدراسة إلى وجود علاقة ارتباط طردية ذات دلاله إحصائية للعنصر البشري، التقنيات الحديثة والثقافة التنظيمية على كفاءة الأداء الوظيفي بالقطاع الحكومي بسلطنة عمان عند مستوى دلالة إحصائية (01.0). كما وجدت الدراسة عدم وجود أثر ذي دلالة إحصائية عند مستوى الدلالة الإحصائية0.05) ) لبعد الأزمات على كفاءة الأداء الوظيفي. وقدمت الدراسة بعض التوصيات أهمها: العمل على تبني استراتيجيات واضحة من قبل المؤسسات لمواجهة الأزمات وإنشاء إدارات مختصة بهذا الشأن .
تحليل رسائل كليات إدارة الأعمال بالجامعات السعودية
Authors: الفلاح خالد 
Published: October 2022

تستهدف هذه الورقة تحليل عبارات "رسالة" كليات إدارة الأعمال في المملكة العربية السعودية. تم الاقتصار على كليات إدارة الأعمال (27) بالجامعات الحكومية السعودية (ليس الأهلية /الخاصة) لهذه الدراسة، للتباين الواضح في الأهداف ومصادر التمويل. حيث تم التحصّل على عبارات رسائلها من مواقعها الرسمية على الشبكة العنكبوتية العالمية. وتم تبني أسلوب تحليل المحتوى كأداة رئيسة في تحليل البيانات. كذلك تم تطبيق تقنية (السحابة الكلماتية) لتوفير دعم أكبر لقيمة التحليل النوعي في هذه الدراسة. يقدّم هذا العمل العديد من النتائج الجديرة بالاهتمام، (1) يتراوح طول عبارات الرسالة من 12 إلى 60 كلمة وهو أقل بكثير من المعيار الدولي الموصى به، والبالغ 250 كلمة، (2) طول عبارات الرسائل أكبر من عبارات الرؤية ذات الصلة، (3) ظهرت "التقنية" على أنها من أقل المصطلحات ظهورا في عبارات الرسالة، (4) ظهرت مفردات "العملاء" و"المنتجات والخدمات" و"الاهتمام بالصورة العامة" باعتبارها المكونات الأكثر تكرارا وظهورا في عبارات الرسالة، (5) ثلاثة موضوعات رئيسة تمت ملاحظة تكرارها في عبارات الرسالة وتشمل "تلبية احتياجات سوق العمل" و"تقديم البرامج" و"خدمة المنطقة والمجتمع". تم تقديم توصيات عديدة للأكاديميين وصانعي السياسات والتي ستسهم في تطوير معايير مستقلة لتقييم عبارات رسائل المؤسسات التعليمية. تم تقييد نتائج المستخلصة لهذا العمل في ضوء المحتوى الموجود على المواقع الرسمية الإلكترونية.