bluuebunny/crossref_metadata_2025_split huggingface dataset:
“Atypical” Mild Clinical Presentation in Elderly Patients With Ruptured Intracranial Aneurysm: Causes and Clinical Characteristics
Authors: Wen Dingke , Chen Ruiqi , Zhang Tianjie , Li Hao , Zheng Jun , Fu Wei , You Chao , Ma Lu 
Published: July 2022

ObjectiveThunderclap-like severe headache or consciousness disturbance is the common “typical” clinical presentation after aneurysmal subarachnoid hemorrhage (aSAH); however, a slowly developing “atypical” clinical pattern, with mild headache, vomiting, or dizziness, is frequently noted in elderly patients. The aim of this study was to evaluate the clinical characteristics of this “atypical” subgroup, as well as related factors associated with the presence of these mild symptoms.MethodsThe data of 176 elderly patients (≥70 years old) with ruptured intracranial aneurysms (IAs) treated at our center from January 2016 to January 2020 were retrospectively collected and analyzed. The patients were divided into “typical” and “atypical” groups based on their initial and development of clinical symptoms after the diagnosis of aSAH. Intergroup differences were analyzed, and factors related to the presence of these two clinical patterns were explored through multiple logistic regression analyses.ResultsDespite significant admission delay (P &lt; 0.001) caused by mild initial symptoms with slow development, patients in the “atypical” group achieved better clinical prognosis, as indicated by a significantly higher favourable outcome ratio and lower death rate upon discharge and at different time points during the 1-year follow-up, than the “typical” group (P &lt; 0.05). Multiple logistic regression analysis revealed that modified Fisher grade III-IV (OR = 11.182, P = 0.003), brain atrophy (OR = 10.010, P = 0.001), a larger lesion diameter (OR = 1.287, P &lt; 0.001) and current smoking (OR = 5.728, P &lt; 0.001) were independently associated with the presence of “typical” symptoms. Aneurysms with wide necks (OR = 0.013, P &lt; 0.001) were independently associated with the presence of “atypical” symptoms.Conclusions“Atypical” presentations, with mild clinical symptoms and slow development, were commonly recorded in elderly patients after the onset of aSAH. Despite the prolonged admission delay, these “atypical” patients achieved better clinical outcomes than those with “typical” symptoms. Modified Fisher grade (III-IV), current smoking, brain atrophy and larger lesion diameter were factors predictive of “typical” symptoms, while aneurysms with wide necks were independently associated with “atypical” symptoms.
Surgical Management of Cholecystoenteric Fistula in Patients With and Without Gallstone Ileus: An Experience of 29 Cases
Authors: Huang Shi-fei , Han Ye-hong , Chen Jie , Zhang Jun , Huang Hai 
Published: July 2022

BackgroundCholecystoenteric fistula (CEF) is an uncommon complication of cholelithiasis. Here, we report our experience on diagnostic methods and surgical management of CEF patients with and without gallstone ileus (GI).MethodsThis is a retrospective cases series over an 11-year period (2011–2022). Data analyzed included preoperative characteristics, ultrasound, imaging features, operation findings and postoperative course.ResultsA total of 29 patients diagnosed with CEF were enrolled, 51.7% (15/29) of whom were female, with a median age of 66 years (range: 35–96 years). With regards to subtype distribution, seventeen patients had cholecystoduodenal fistula (CDF), six had cholecystoconlonic fistula (CCF), three exhibited cholecystogastric fistula (CGF), one CDF combination with CCF and two CDF combination with type I Mirizzi syndrome. Twelve patients presented with gallstone ileus, and received one stage procedure or simple Enterolithotomy. The median operation time and blood loss of 157 min (range: 65–360 min) and 40 ml (range: 10–450 ml), respectively. Surgical complications, evidenced by fistula recurrence, were recorded in three patients (3/22; 13.6%), while four (4/29; 13.8%) and one patient (1/29; 3.4%) presented with wound infection and residual stone in common bile duct, respectively. No deaths were reported in our study.ConclusionCEF is a rare complication of gallstone disease that is occasionally found during operation. To date, no consensus has been reached regarding efficacious treatment therapies for CEF patients. For a CEF patient with GI, one stage procedure should be selected prudently, while simple Enterolithotomy would be a mainstream choice for relieving bowel obstruction.
Case Report: A New Geographic Area for the Presence of the Zoonotic Ocular Nematode, Onchocerca lupi in Romania
Authors: Deak Georgiana , Toader Serenela , Soare Diana Gabriela , Ionică Angela Monica , Taulescu Marian , Mihalca Andrei Daniel 
Published: July 2022

IntroductionOnchocerca lupi is a zoonotic parasite of carnivores reported in countries from Europe, North America, Asia and Africa. In Romania, canine ocular onchocercosis was first reported in dogs in 2016 from Târgovişte (Dâmboviţa County) and Oneşti (Bacău County) and more recently, it was detected in an adult stray dog exported to UK from an unspecified location in Romania.MethodsA 4-years old male mongrel dog was referred to a private veterinary clinic in Năvodari (Constanţa County), Romania due to ocular disorders. The dog was originally from a public dog shelter in Balş (Olt County) and transferred in June 2020 to a dog shelter in Medgidia (Constanţa County). A cytological examination followed by surgical removal of the granuloma localized at the internal angle of the right eye, and molecular identification of the extracted nematode were done.ResultsThe cytological examination confirmed a parasitic granuloma. Skin biopsy and PCR confirmed the infection with O. lupi. Two doses of moxidectin and imidacloprid were administered after the surgery. No relapse observed after a period of follo-up of 11 months.ConclusionOnchocerca lupi is present in dogs from Romania with its actual distribution remaining unknown.
Socioeconomic Disparities in Disability-Free Life Expectancy and Life Expectancy Among Older Chinese Adults From a 7-Year Prospective Cohort Study
Authors: Zhan Yuanyuan , Han Yaofeng , Fang Ya 
Published: July 2022

Objectives: We examined the magnitude and determinants of socioeconomic disparities in disability-free life expectancy and life expectancy at age 65 (DFLE65 and LE65) in China.Methods: Data from Chinese Longitudinal Healthy Longevity Survey collected during 2011–2018 (8,184 participants aged ≥65) were used. Socioeconomic status (SES) was measured by economic status (ES), and education, respectively. Multistate Markov models and microsimulations were fitted to estimate DFLE65 and LE65.Results: LE65 between high- and low-ES groups differed by 2.20 years for males and 2.04 years for females. The DFLE65 disparity in ES was 1.51 and 1.29 years for males and females, respectively. Not undergoing physical examinations, inadequate fruit/vegetable intake, and stress contributed to 35.10% and 57.36% of DFLE65 disparity in ES, as well as 26.36% and 42.65% of LE65 disparity for males and females, respectively. These disparities in education and ES were of a similar magnitude, while the above factors contributed little to education disparity.Conclusion: Socioeconomic disparities in DFLE65 and LE65 existed in China. Physical examination, fruit/vegetable intake and stress partly explained these disparities.
Genome-Wide Identification of TaSAUR Gene Family Members in Hexaploid Wheat and Functional Characterization of TaSAUR66-5B in Improving Nitrogen Use Efficiency
Authors: Lv Weizeng , He Xue , Guo Haojuan , Lan Haibin , Jiao Yanqing , Li Le , Lian Yanhao , Wang Zhiqiang , Xin Zeyu , Ren Yongzhe , Lin Tongbao 
Published: July 2022

Excessive input of nitrogen fertilizer not only causes a great waste of resources but brings about a series of ecological and environmental problems. Although Small Auxin Up-regulated RNAs (SAURs) participate in diverse biological processes, the function of SAURs in the nitrogen starvation response has not been well-studied. Here, we identified 308 TaSAURs in wheat and divided them into 10 subfamilies. The promoter regions of most TaSAURs contain hormone responsive elements, and their expression levels change under the treatment of different hormones, such as IAA, MeJA, and ABA. Interestingly, overexpression of one of the TaSAUR family members, a nitrogen starvation responsive gene, TaSAUR66-5B, can promote the growth of Arabidopsis and wheat roots. In addition, overexpression of TaSAUR66-5B in Arabidopsis up-regulates the expression levels of auxin biosynthesis related genes, suggesting that overexpression TaSAUR66-5B may promote root growth by increasing the biosynthesis of auxin. Furthermore, overexpression of TaSAUR66-5B in wheat can increase the biomass and grain yields of transgenic plants, as well as the nitrogen concentration and accumulation of both shoots and grains, especially under low nitrogen conditions. This study provides important genomic information of the TaSAUR gene family and lays a foundation for elucidating the functions of TaSAURs in improving nitrogen utilization efficiency in wheat.
PERANCANGAN MODEL SIMULASI DAN PERBAIKAN SISTEM: STUDI KASUS PELAYANAN PERBANKAN
Authors: Imansuri Febriza 
Published: July 2022

Penelitian ini membahas penerapan model simulasi sistem antrian yang digunakan dalam perbaikan sistem di perbankan. Metode simulasi digunakan untuk memodelkan keadaan sistem saat ini dengan software Arena, dengan mempelajari sistem nyata dan mengeliminasi kendala dengan menggunakan skenario perbaikan yang telah ditetapkan. Sistem nyata tersebut dipelajari dengan cara membuat analisis input, output, control dan mechanism dan selanjutnya membuat Activity Cycle Diagram, Event Graph dan flowchart algoritma simulasi. Data yang dikumpulkan berupa waktu kedatangan dan waktu pelayanan pelanggan pada server teller, customer service dan mesin ATM yang merupakan bagian dari sistem nyata perbankan. Perbaikan sistem dilakukan dengan menetapkan dua skenario yaitu pengurangan server CS dan Penambahan server ATM. Berdasarkan hasil analisis keluaran didapatkan bahwa simulasi model aktual merupakan simulasi yang terpilih. Hal ini dikarenakan model aktual sudah menjadi sistem yang terbaik untuk sistem perbankan tersebut.
Kata Kunci: Antrian, model simulasi, sistem perbankan
USULAN PENINGKATAN KUALITAS PELAYANAN MENGGUNAKAN INTEGRASI IMPORTANCE PERFORMANCE ANALYSIS, KANO, DAN ANALISIS TRIZ DI KAFE NGOFFEE.ID
Authors: Yuniati Yoanita , Prasetyo Sigit 
Published: July 2022

Ngoffee.id merupakan kafe yang saat ini dihadapkan pada permasalahan kualitas pelayanan, diantaranya penyajian pesanan yang lambat, fasilitas yang tidak memadai misal pada lahan parkir, dan protokol kesehatan yang belum optimal. Penelitian ditujukan untuk menghasilkan rancangan usulan peningkatan kualitas layanan di Kafe Ngoffee.id. Penelitian dilakukan menggunakan integrasi metode Importance Performance Analysis dengan Kano, serta analisis TRIZ untuk memperoleh usulan peningkatan kualitas. Hasil penyebaran kuesioner terhadap 100 responden diperoleh rataan tingkat kepuasan 3,15 dan tingkat kepentingan 2,95 dari skala 1 sampai 5. Hasil analisis TRIZ terhadap 4 atribut prioritas menghasilkan usulan peningkatan kualitas, yang terdiri dari atribut X13 mengenai kecepatan pelayanan kafe dalam menyajikan pesanan dengan usulan kafe memberikan snack dan minuman gratis kepada pelanggan, atribut X3 mengenai ketersediaan lahan parkir dengan usulan kafe melakukan kerjasama dengan pengelola lain terkait lahan parkir. Atribut berikutnya X19 mengenai penggunaan masker dan atribut X21 mengenai posisi tempat duduk sesuai prokes, untuk kedua atribut tersebut usulan yang dihasilkan yaitu penyediaan masker serta mengatur posisi tempat duduk sesuai anjuran protokol kesehatan. Usulan tersebut diharapkan mampu meningkatkan kualitas pelayanan kafe Ngoffee.id sehingga dapat menarik minat pengunjung kafe.
Caldwell's Educational Service on ‘Karisal Mann’ (Black Soil)
Authors: J Raja Sornam 
Published: July 2022

The Gurukul system of education was only available in a few places in ancient India. Christian missionaries transformed this condition, establishing the current educational system and bringing education to all people, regardless of caste, creed, colour, or social rank. Robert Caldwell, in particular, made significant contribution in providing education to the poor in South India throughout the nineteenth century. In Idayangudi, Tirunelveli, he undertook various reformatory activities in the areas of gospel, Tamil language, society, medicine, and education. Robert Caldwell was born in Antrim, Ireland, in 1814. He went to Glasgow University to study. He was an expert in English, Tamil, and Religious Texts, as well as art. He was fluent in Tamil, English, Greek, Telugu, and Sanskrit, among other languages. In 1841, he went to Tirunelveli's Idayangudi in South India as a missionary under the London Missionary Society. He revitalised the boy's school which was begun by Rev. Iranius. In 1842, Caldwell also founded the Girl's School. These schools taught subjects like Tamil, English, Geography, and History. He founded Anglo Vernacular Schools to teach English and Tamil letters to youngsters who did not know English. He established schools in places like Tharuvai, Ramanathapuram, Samugarengapuram, Kulasegaran Pattinam, Azhvar Thirunagari, Tuticorin, Arumangalam, Thenthiruperai, and Thatanpadam. Caldwell stayed in Idayangudi for more than 50 years, bringing about significant changes for the illiterate. Caldwell's legacy lives on in the hearts of the people and has fused with the Chernozem soil, as evidenced by educational institutions and researchers who have benefited from them.
Customs of Rajus’ Community
Authors: S Sathya 
Published: July 2022

The Rajus’ community migrated from Andhra Pradesh to South Tamilnadu and settled there permanently in the black soiled region before 600 years ago due to regimental changes. They engaged themselves in Agro-based occupation after their displacement. As they concentrated more on the clothing business, harvesting cotton had become their field of interest, and thus they adapted their lifestyle on the land of black soil.variety of rituals are followed by various communities globally. Accordingly, the communit people of the Rajus' follows several rituals from their birth to death. As part of their ritual, all the things invariably used on the occasions of ceremonies and their fixed lifestyle represent some hidden scientific facts. Those are researched and interpreted to prove the significance of rituals in human life which is strongly connected with nature. This research paper lays emphasis on the main aim of the customs and rituals of the humans. They are connected with the formidable factors strengthening the physical energy. Paying attention to the ancient rituals and customs are sadly on the decrease in the contemporary period. The evidence of diminished rituals can be seen in temples and their way of celebrating festivals. The purpose of the research is to manifest the necessity of restoring the significance of rituals framed scientifically by our ancestors. This research will positively help to discern the hidden scientific facts in the rituals for close and prompt follow up of the same.
STUDY OF THE INFLUENCE OF INTENTIONAL ELECTROMAGNETIC IMPACTS ON THE LORAWAN BASE STATION
Authors: ФИЛИН Е.Д. , ОВЧИННИКОВ А.О. , БОРОДИН А.С. , МЫРОВА Л.О. , КИРИЧЕК Р.В. , ИСАЕНКО Д.И. 
Published: July 2022

Представлены результаты экспериментального исследования влияния преднамеренных электромагнитных воздействий в виде сверхширокополосных электромагнитных помех на узлы энергоэффективной сети дальнего радиуса действия. В качестве объекта исследования использовалась типовая базовая станция LoRaWAN,на которую осуществлялось направленное воздействие согласно ГОСТ Р 52863-2007. По результатам исследования выявлены пороговые уровни, при которых были зафиксированы сбои и отказы в работе базовой станции LPWAN.
The article presents the results of an experimental study on the influence of intentional electromagnetic impacts in the form of ultra-broadband electromagnetic interference on the nodes of an energy-efficient long-range network. As an object of study, a typical LoRaWAN base station was used, which was subjected to a directional impact in accordance with GOST R 52863-2007. According to the results of the study, threshold levels were identified at which malfunctions and failures in the operation of the LPWAN base station were recorded.
Identifikasi dan Uji Kestabilan Tanin dari Daging Biji Pangi (Pangium edule Reinw.) sebagai Bahan Pewarna Alami
Authors: Datu Fransiska N.S , Hasri Hasri , Pratiwi Diana Eka 
Published: July 2022

ABSTRAKPenelitian ini adalah penelitian eksplorasi untuk mengetahui jenis tanin, penetapan kadar tanin dan uji kestabilan tanin dari daging biji Pangi (Pangium edule Reinw.) dengan metode spektrofotometri menggunakan UV-VIS. Daging biji pangi diekstraksi dengan etanol 70%. Hasil uji kualitatif menggunakan pereaksi FeCl3 1%, Asam Asetat 10%, Pb Asetat 10%, HCl, Bromine, dan Tes Katekin, menunjukkan daging biji pangi termasuk jenis tanin terhidrolisis dengan kadar tanin rata-rata 15,54 % dan stabil pada suhu 80 – 100 ºC. Kata kunci : Pangium edule Reinw., Kadar Tanin, Spektrofotometri, UV-VIS ABSTRACTThis research for determining the kind of tannin and tannin assay and also the stability testing of tannin from meat seed of pangi has been done by using spectrophotometric method with UV-VIS. The meat seed of pangi fruit was extracted using 70% ethanol. The extract was tested using qualitative assay with reagent. Base on Qualitative test result with a reagent FeCl3 1%, Acetate Acid 10%, Pb Acetate 10%, HCl, bromine and catechin test,was obtained that meat seed of pangi contain hydrolyzed tannin. Tannin level was obtained on average 15.54 % and stable at a temperature of 80 – 1000C. Keywords: Pangium edule Reinw., Tannin assay, Spectrophotometric, UV-VIS
Isolasi dan Identifikasi Senyawa Metabolit Sekunder Ekstrak n-Heksana Kulit Batang Mangrove Pedada (Sonneratia Caseolaris)
Authors: Prastika Ike , Herawati Netti , Wijaya Mohammad 
Published: July 2022

ABSTRAKPenelitian ini bertujuan untuk mengisolasi dan mengidentifikasi senyawa metabolit sekunder ekstrak n-heksana dari kulit batang Mangrove Pedada (Sonneratia caseolaris), yang diperoleh dari daerah pinggiran Sungai Tallo Kelurahan Paccerakkang, Kota Makassar, Sulawesi Selatan. Senyawa ini diperoleh melalui beberapa metode yaitu fraksinasi, pemurnian dan identifikasi. Fraksinasi dilakukan dengan cara kromatografi kolom flash; pemurnian dengan rekristalisasi dan identifikasi menggunakan uji warna, titik leleh, kelarutan, KLT dan uji spektroskopi. Kristal yang diperoleh dari hasil penelitian berbentuk serbuk berwarna putih dengan titik leleh 140 oC. Senyawa ini bereaksi positif dengan pereaksi Liebermann-Burchard yang menunjukkan golongan terpenoid. Identifikasi dengan spektroskopi infra merah memberikan serapan pada bilangan gelombang (cm1) : 1058,92 (-CO); 1462,04 (-CH) dan1377,17 (-CH); 1641,42 (C=C); 2958,80 (-C), dan 2895,15 (-C); 3427,51 (-OH); 962,48 (=C),. Berdasarkan uji pereaksi LB dan data IR maka senyawa tersebut adalah terpenoidKata kunci : Pedada, Sonneratia caseolaris., Terpenoid ABSTRACTThis research is aimed to isolate and Identification of secondary metabolite compound Extract of n-Hexane from Pedada Mangrove (Sonneratia Caseolaris) who come from Tallo River side, Paccerakkang district, Makassar City, Sulawesi Selatan. This compound was obtained by some methods, namely, fractionation, purification and identification. The fractionation is carried out by flash coloumn chromatography; purification by recrystallization and identification by colour test, melting point, solubility, thin layer chromatography (TLC), and spectroscopy method. The result of the research shows the white crystal with amorf stoueture who melted on 140 0C. This compound has positive reaction to Liebrmann-Burchard reagen who identified as terpenoid group. Identification with infra red spectrum shows absorption on some wave number (cm-1) are: 1058,92 (-CO); 1462,04 (-CH) dan 1377,17 (-CH); 1641,42 (C=C); 2958,50 (-C), dan 2895,15 (-C); 3427,51 (-OH); 962,48 (=C). Base on LB reagent test and IR spectrum , the compound is coming from terpenoid group. Key word : Pedada, Sonneratia Caseolaris, Terpenoid
Pengaruh Suhu Dan Waktu Pemanasan Terhadap Stabilitas Pigmen Antosianin Ekstrak Asam Sitrat Kulit Buah Naga Merah (Hylocereus polyrizus) Dan Aplikasi Pada Bahan Pangan
Authors: Nasrullah Nasrullah , Husain Halimah , Syahrir Muh. 
Published: July 2022

ABSTRAKPenelitian ini merupakan penelitian eksperimen bertujuan untuk mengetahui stabilitas ekstrak pigmen antosianin kulit buah naga merah (Hylocereus polyrizus) terhadap suhu dan waktu pemanasan serta ketahanan warna antosianin kulit buah naga merah pada bahan pangan. Ekstraksi kulit buah naga merah dilakukan dengan metode maserasi menggunakan pelarut asam sitrat 10% : air (6:1). Pengaruh suhu 400C, 500C dan 600C terhadap stabilitas pigmen antosianin dilakukan pada rentang waktu 5 menit, 15 menit, 30 menit, 45 menit dan 60 menit. Selanjutnya dilakukan pengukuran absorbansi sampel pada spektrofotometer UV-Vis dengan λ maks 520,00. Data hasil pengukuran menunjukkan bahwa pigmen antosianin stabil pada rentang suhu 400C - 500C dengan lama pemanasan 30 menit, 45 menit dan 60 menit. Kata Kunci : Kulit buah naga merah, suhu, waktu.ABSTRACT This research is an experimental study with aim’s to know the stability of anthocyanin pigment extract from red dragon fruit skin (Hylocereus polyrizus) on temperature, heating time and the anthocyanin color resistance of red dragon fruit skin on foodstuffs. Extraction of dragon fruit skin was done by maceration method using 10% citric acid solvent: water (6: 1). The effect of temperature of 400C, 500C and 600C on the stability of anthocyanin pigments was carried out in the time range of 5 minutes, 15 minutes, 30 minutes, 45 minutes and 60 minutes. Then the absorbance measurements of the samples in UV-Vis spectrophotometer were carried out with λ max 520.00. The measoroment result showed that anthocyanin pigment is stable on the temperature range 400C - 500C with heating time of 30 minutes, 45 minutes and 60 minutes. Keywords: Red dragon fruit skin, temperature, time.