bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thin-catheter Surfactant Application for Respiratory Distress Syndrome
in Spontaneously Breathing Preterm Infants: A Meta-analysis of Randomized
Clinical Trials
Authors: Peinemann Frank , Kesler Hanan , Lohmeier Klaus , Hoehn Thomas , Kribs Angela 
Published: April 2022

Background:
Surfactant application by a thin catheter represented by the term less inva-sive surfactant administration (LISA) for respiratory distress syndrome in spontaneously breathing preterm infants was developed as an alternative to endotracheal intubation.

Method:
We conducted a meta-analysis to assess the effects of LISA when compared to the so-called intubation-surfactant-extubation (INSURE) and the standard endotracheal intubation and me-chanical ventilation (MV). The primary outcome was the composite incidence of death or bron-chopulmonary dysplasia at a postmenstrual age of 36 weeks. The secondary outcome was the com-posite incidence of seven other severe adverse events. On 06 October 2021, we searched random-ized clinical trials (RCTs) in PubMed, the Cochrane Library, ClinicalTrials.gov, and the ICTRP Registry.

Results:
We included 18 RCTs. The pooled data on the primary outcome favored LISA when com-pared to either INSURE (risk ratio 0.67; 95% CI, 0.51 to 0.88) or MV (risk ratio 0.78; 95% CI, 0.61 to 0.99). The pooled data on the second outcome also favored LISA when compared to INSURE (risk ratio 0.75; 95% CI, 0.60 to 0.94) and MV (risk ratio 0.73; 95% CI, 0.55 to 0.96).

Conclusions:
The findings showed that surfactant application by non-intubation respiratory support and the use of a thin catheter may decrease the composite risk of death or bronchopulmonary dys-plasia. The included data support the view that LISA should be considered the preferred treatment option in eligible infants.
Intrahepatic Portosystemic Shunt via the Right Adrenal Vein in an
Asymptomatic Cirrhotic Patient
Authors: Gündoğdu Elif , Küçükhüseyin Abdullah , Yazici Celal , Kebapçi Mahmut 
Published: April 2022

Purpose:
Intrahepatic portosystemic shunts (PSSs) draining to the inferior vena cava (IVC)
via the right adrenal vein has been reported as very rare, and all the patients who have been recorded
have had hepatic encephalopathy. Here, we present a patient with intrahepatic PSS via the right adrenal
vein diagnosed incidentally without encephalopathy.

Case Presentation:
A 51-year-old patient, who was diagnosed with chronic liver parenchyma disease
and a suspecting nodule on the ultrasound was examined by computed tomography (CT) and magnetic
resonance imaging (MRI). A 4 cm in diameter hepatocellular carcinoma (HCC) was detected. In addition
to HCC, an abnormal shunt between the right posterior portal vein and the IVC via the right adrenal
vein was also detected.

Results:
To the best of our knowledge, this is the first case with intrahepatic PSS via the right adrenal
vein diagnosed incidentally in the absence of encephalopathy and the fourth case with this abnormal
shunt in English literature.

Conclusions:
Intrahepatic PSS via the right adrenal vein is rare. It may be asymptomatic at the time of
diagnosis but has the potential to cause various problems, later on, especially hepatic encephalopathy.
The radiologist must be aware of this abnormal shunt.
Even After Vaccination, is the Second Wave of COVID-19 in India More
Dangerous?
Authors: Veer Karan , Kumar Pooja , Kumar Sachin 
Published: April 2022

Abstract:
The COVID-19 infection has already had a significant impact on the global health system. Nowadays, the second wave of the disease is surging in India. One significant difference between the two waves is that they are too virulent in terms of infection rate. During the surge of the second wave, the mortality rate is highest in the age group of 50-70 years old. In three age groups, below 10, 30 to 40 years, and above 80, the mortality rate is increased. Symptoms are also different in both waves. The second wave is becoming more dangerous due to the double mutant variant of the virus.
In silico Study of Some Dexamethasone Analogs and Derivatives against
SARs-CoV-2 Target: A Cost-effective Alternative to Remdesivir for Various
COVID Phases
Authors: Pandey Ruchi , Dubey Itishree , Ahmad Iqrar , Mahapatra Debarshi Kar , Patel Harun , Kumar Pranesh 
Published: April 2022

Aim:
The black market for Remdesivir for the treatment of COVID-19 is surging in the
world. This condition leads to the uprising of drugs from the common hospital inventory, of which
Dexamethasone is an effective weapon to be employed against the coronavirus.

Background:
Remdesivir is an intravenous nucleotide prodrug of an adenosine analog. Dexamethasone
was tested in hospitalized patients with COVID-19 in the UK’s national clinical trial and
was found to benefit critically ill patients. Therefore, it could be a better alternative.

Objective:
A computational approach of molecular docking was performed to determine the binding
interactions ability between the selected 3D-models of COVID-19 protease and inflammatory targets
with suggested modified ligand compounds through Autodock v.1.5.6 software that also establishes
the plausible mechanism.

Method:
Dexamethasone had a constructive response where we utilized the structural modification
technique in which molecules (icomethasone, betnesol, topicort, flumethasone, paramethasone, triamcinolone,
and doxi-betasol) bearing the same pharmacophore as in dexamethasone (ring-A as it is
responsible for the binding of the compound to the steroidal receptor), were selected from available
drug bank to observe the response of these modified structures against SARs-CoV-2. Desmond
Simulation Package was used to run MD simulations for 100 ns following the docking calculations
to assess the steady nature and conformational stability of the Dexamethasone-17-acetate-SARs-
CoV-2 main protease complexes.

Result:
Dexamethasone-17-acetate, the best analog, demonstrated a better pharmacological response
than the parent compound and provided information for further designing active inhibitors
against inflammatory targets activated by the coronavirus attack. The maximum RMSD value of the
Cα-backbone of the SARs-CoV-2 main protease protein is 3.6Å, indicating that the Dexamethasone-
17-acetate-6LU7 protein complex was retained continuously throughout the simulation time.

Conclusion:
The present investigation was a search for inhibitors that will help recover patients
suffering from COVID and for prophylactic use.
Health-Related Quality of Life of HIV-Positive and HIV-Negative Pregnant Women in an Impoverished Area: Cross-sectional Study
Authors: Qu Shuiling , Wang Ailing , Wang Xiaoyan , Yang Yehuan , Pan Xiaoping , Zhang Tong 
Published: April 2022

Background
Liangshan prefecture of Sichuan province was an impoverished mountainous area in China, where the annual number of HIV-positive pregnant women accounted for approximately 10% of China’s total population in the decades before 2020. In general, pregnant women living here are likely to be physically and mentally different from those in other places.

Objective
This study aims to explore the health-related quality of life (HRQoL) of pregnant women living with HIV in an impoverished area.

Methods
From December 2018 to January 2019, HIV-positive and HIV-negative parturients within 18 months after delivery were recruited in Liangshan Prefecture, Sichuan Province. Questionnaires were designed to collect their demographic data, while the EuroQol 5-Dimension, 3-Level questionnaire was used to measure their HRQoL when they were in the second trimester from 4 to 6 months of pregnancy, and their quantitative health scores were converted to corresponding healthy utility values by using the Chinese Utility Value Integral System (time trade-off coefficient).

Results
A total of 250 pregnant women (133 HIV-positive and 117 HIV-negative) were enrolled in the study. Among them, 55 (41.35%) and 75 (64.10%) of HIV-positive and HIV-negative pregnant women self-reported full health (healthy state 11111), respectively. The median health utility value of the 250 pregnant women was 0.961 (IQR –0.046 to 0.961), and those of the HIV-positive and HIV-negative pregnant women were 0.875 (0.424-0.961) and 0.961 (IQR –0.046 to 0.961), respectively. We observed a significant difference only in the dimension of anxiety or depression between the two groups (P=.002) and no significant difference in the distribution of health utility indices between the two groups in terms of maternal age, education level, occupation, annual household income, prenatal care visits, family size, and medical insurance category. Multivariate ordinal logistic regression analysis showed that age (odds ratio [OR] 0.62, P<.05) and prenatal care visit (OR 0.29, P<.01) were independent risk factors for health status.

Conclusions
Most pregnant women self-reported satisfactory HRQoL in this impoverished mountainous area. HIV-negative pregnant women had an edge over HIV-positive pregnant women, and there were significant differences in anxiety or depression dimensions between the two groups.
ESTRATÉGIAS DIDÁTICAS POTENCIALIZADORAS NO ENSINO E APRENDIZAGEM DE QUÍMICA
Authors: Paiva Maria Mabelle Pereira Costa , Fonseca Aluísio Marques da , Colares Regilany Paulo 
Published: April 2022

Quando se trata do Ensino de Química nas escolas, percebe-se que, na maioria das vezes, à abordagem se restringe ao tradicional, em que o professor transmite conhecimentos e os aprendizes são meros receptores. Além disso, é um componente curricular visto pelos estudantes de difícil compreensão, apresentando dificuldades e baixos rendimentos. Diante disso, esta pesquisa visa debater estratégias didáticas potencializadoras no ensino e aprendizagem de Química, com objetivo de promover aulas contextualizadas, com linguagem acessível e estimular os discentes a serem protagonistas na busca de conhecimentos. Inicialmente, foram realizadas pesquisas sobre estratégias que promovam um maior aproveitamento nas aulas de Química. E em seguida, foram confeccionados e aplicados jogos didáticos nas turmas das 2ª e 3ª séries do ensino médio, em uma escola pública, localizada em Barreira-CE. Para tanto, foi utilizada a pesquisa qualitativa, com levantamento de informações e dados durante a aplicação dos jogos. Os resultados apontam que as estratégias metodológicas utilizadas contribuíram para a melhoria do processo de ensino e aprendizagem de Química, possibilitando aos discentes, e ao docente, uma experiência motivadora na construção do conhecimento.
La empresa familiar y su situación actual en Mérida, Yucatán
Authors: Jiménez Diez Olivia , Ojeda López Ruth N. , Mul Encalada Jennifer , López Canto Leonor E. 
Published: April 2022

La presente investigación es cuantitativa descriptiva, no experimental y transversal y se propuso como objetivo general realizar un diagnóstico de las empresas familiares en la ciudad de Mérida, Yucatán. Para ello, se consideraron los siguientes aspectos: datos demográficos, retos y prioridades, propiedad, planeación de sucesión y remuneración a directivos, y resolución de conflictos. Y se utilizó el instrumento desarrollado por San Martín y Durán (2017), cuyo alfa de Cronbach para esta investigación fue de 0.768. Los resultados muestran tres grandes áreas de oportunidad para las empresas familiares: 1) el desarrollo de una planeación estratégica, ya que 37.8 % de los representantes de las empresas encuestadas dice contar con un documento escrito al respecto; 2) el desarrollo e implementación de un plan de sucesión, debido a que 41 % cuenta con uno y es una herramienta vital para la permanencia en el mercado y 3) la definición e implementación de un protocolo, ya que solo 21 % de las empresas encuestadas cuenta con uno y es precisamente este documento el que muestra el consenso familiar y evita el desgaste de la empresa y la familia misma.
DAMPAK TAMAN WISATA TALANG INDAH TERHADAP PEREKONOMIAN MASYARAKAT DI KABUPATEN PRINGSEWU
Authors: Desiwi Romaniartini , Prasmatiwi Fembriarti Erry , Marlina Lina 
Published: April 2022

Talang Indah Tourism Park is a tourist attraction located in Pringsewu Regency. The purpose of this research is to analyze the impact of Talang Indah Park on the economy of the people in the Pringsewu Regency. The research method used was a survey method with 75 visitor respondents, 12 business actors, and 23 labor respondents. The data analysis method used is the Keynesian multiplier effect, by calculating the direct impact, indirect impact, and induced impact. This study concludes that the direct impact that is felt is IDR24,405,000.00 per month, the indirect impact is IDR35,770,000.00 per month, and the induced impact is IDR42,402,000.00 per month. The Keynesian Income Multiplier value at Talang Indah Park is 5.20, so it can be concluded that Talang Indah Tourism Park has economic impact on tourism activities.Key words: direct, indirect, induced, multiplier effect, tourism park
ANALISIS PREFERENSI KONSUMEN KEDAI KOPI DI KOTA BANDARLAMPUNG
Authors: Permadi Rizky Agung , Sayekti Wuryaningsih Dwi , Abidin Zainal 
Published: April 2022

The growth of coffee shop is very fast recently in Bandarlampung with different characteristics that causes various consumer preference. This research aims to analyze consumer preferences as well as the level of performance and importance of coffee shop attributes in Bandarlampung. This study used a survey method involving 100 respondents with analytical tools, namely Conjoint Analysis, Customer Satification Index, and Important Performance Analysis. The research location was determined randomly, namely Bun Kopi, 20 Kopi, Diskusi Kopi, Kala Senja Café, and Rencana Kopi. The study shows that consumer preferences for coffee shops in Bandarlampung City were include complete facilities, such as cool and comfortable atmosphere, the taste of soft coffee drinks, modern industrialist building design, and fast service. The study also shows that customers are satisfied with the coffee shop. The taste attribute has the highest level of performance. Furthermore the attributes of facilities, services, and atmosphere have less performance, suggesting that these attributes need improvements. Meanwhile building design attribute is not priority for costumer. Key words: attribute, coffee shop, preference.
ANALISIS SIKAP, LOYALITAS, DAN FAKTOR-FAKTOR YANG MEMENGARUHI PEMBELIAN MINYAK GORENG KEMASAN BIMOLI DAN SANIA DI PASAR TRADISIONAL DI KOTA BANDAR LAMPUNG
Authors: Togatorop Roylando P , Lestari Dyah Aring Hepiana , Sayekti Wuryaningsih Dwi 
Published: April 2022

This study aims to determine consumers’ attitudes and the factors that influence purchasing of Bimoli and Sania cooking oil packaging at markets in Bandar Lampung. This research was conducted at five markets namely Rakyat Tani, Tempel Waykandis, Waykandis, Tempel Cahaya, and Tempel Gotong Royong. The number of consumer respondents was 60 people, recruited accidentally. Research data were analyzed using multiatribute Fishbein and multiple linear regression. Consumers’ attitude showed that the Bimoli brand and Sania cooking oil packaging got the highest scores. Consumers’ purchasing of Bimoli cooking oil packaging was influenced by the price of Bimoli cooking oil packaging, family income, and family members. Consumers’ purchasing Sania cooking oil packaging was influenced by the price of Sania cooking oil packaging, the price of bulk cooking oil, the price of Tropical cooking oil packaging, and the price of Kunci Mas cooking oil packaging. Key words: attitudes, consumers’ purchasing, cooking oil packaging
Peer Attachment dengan Regulasi Emosi Pada Santri
Authors: Luthfi Intan Muthia , Husni Desma 
Published: April 2022

Penelitian ini bertujuan untuk mengetahui hubungan antara peer attachment dengan regulasi emosi (cognitive reappraisal dan expressive suppression) pada santri Dar El Hikmah Pekanbaru. Subjek penelitian terdiri dari 220 santri dari kelas VIII dan IX. Penelitian ini menggunakan skala regulasi emosi (ERQ-CA) dan skala peer attachment (IPPA) yang disusun untuk mengukur regulasi emosi cognitive reappraisal, regulasi emosi expressive suppression, dan peer attachment. Analisis data dilakukan dengan menggunakan teknik korelasi product moment. Berdasarkan hasil analisis pearson product moment diperoleh koefisien korelasi r=0,553, p=0,000 (p≤ 0,05) yang berarti bahwa terdapat hubungan antara peer attachment dengan regulasi emosi cognitive reappraisal. Analisis kedua diperoleh hasil r=0,251, p=0,000 (p≤ 0,05) yang berarti bahwa terdapat hubungan antara peer attachment dengan regulasi emosi expressive suppression. Peer attachment yang terbentuk melalui interaksi dan komunikasi membantu santri untuk mengelola emosi saat mengalami masalah, khususnya masalah selama berada di Pondok Pesantren
Kompetensi Multikultural pada Konseling Lesbian Gay Biseksual dan Transgender dalam Perspektif Islam
Authors: Wahyuni Nike , Diniaty Amirah , Meiza Asti 
Published: April 2022

Angka kasus LGBT yang meningkat setiap tahunnya menjadi kekhawatiran dan isu yang harus disikapi bijak dan kompeten oleh konselor dalam praktik konseling. Tulisan ini membahas secara teoritis hasil-hasil penelitian tentang kompetensi multikultural yang harus dimiliki konselor dalam praktik konseling terhadap kasus LGBT dalam perspektif Islam. Gagasan enam kontinum dalam praktik konseling terhadap kasus LGBT yang harus dikuasai konselor meliputi Self, Relationship, Differential of feeling,Identify, Spiritual Intervention dan Acceptane of environmental. Kode Etik American Counseling Association (ACA) mensyaratkan penegasan identitas LGBT, termasuk memvalidasi individu LGBT sebagai bagian dari kompetensi yang harus dikuasai konselor. Selain itu konselor sendiri harus mengenali dirinya sendiri, melakukan penilaian biopsikososial menyeluruh terhadap klien LGBT, tidak menyalahkan, dan menjunjung standar etika. Sebagai konselor muslim, pandangan konselor tentang ajaran Islam yang melarang keras LGBT menjadi norma yang dapat disampaikan pada klien sehingga pembingkaian informasinya menjadi tepat
Sinergitas Orang Tua-Guru dalam Membentuk Karakter Jujur dan Daya Juang Siswa
Authors: Sundari Ayu 
Published: April 2022

Jujur dan daya juang merupakan karakter yang penting bagi siswa. Karakter jujur dan daya juang merupakan modal dasar bagi siswa untuk meraih prestasi akademik maupun non akademik. Artikel ini mencoba membahas bagimana peran orangtua dan guru dalam membentuk karakter jujur dan daya juang siswa, serta membahas dalam perspektif lapangan (pengalaman personal) maupun teoritis. Dalam membentuk karaktet jujur dan daya juang perlu sinergitas semua pihak terutama keluarga (orangtua) dan sekolah (guru). Peran orangtua sangat penting terutama sebagai pembentukan awal karakter jujur dan daya juang. Orangtua berperan sebagai transfer nilai, dan model bagi siswa. Sementara sekolah merupakan salah satu tempat penerapan karakter jujur dan daya juang bagi siswa. Di sekolah, peran guru menjadi signifikan khususnya dalam transfer nilai dalam pembentukan karakter jujur dan daya juang melalui hubungan positif, motivasi, serta lingkungan yang kondusif bagi siswa. Pada akhirnya, sinergitas orangtua dan guru menjadi penting dalam pembentukan karakter jujur dan daya juang siswa.Kata kunci:jujur, daya juang, orangtua, guru
Meningkatkan Kedisiplinan Siswa Melalui Penerapan Konseling Realita
Authors: Khair Muhammad Hubbal , Emliyati Emliyati , Padhli Ilham 
Published: April 2022

Salah satu kompenen tercapainya tujuan pembelajaran di sekolah adalah kedisiplinan. Berdasarkan hasil observasi peneliti pada siswa kelas IX.6 SMP Negeri 9 Pekanbaru diketahui bahwa tingkat kedisiplinannya rendah. Hal ini terlihat dari siswa yang datang ke sekolah tidak tepat waktu, tidak mengerjakan PR, tidak menggunakan atribut dengan lengkap dan keluar masuk kelas ketika proses pembelajaran sedang berlangsung. Konseling realita merupakan alternatif pemecahan masalah untuk membentuk dan meningkatkan kembali kedisiplinan siswai. Penelitian ini dilaksanakan di kelas IX.6 SMP Negeri 9 Pekanbaru pada semester genap tahun pembelajaran 2020/2021 dengan sampel penelitian 9 orang siswa. Hasil penelitian tindakan kelas ini adalah penerapan konseling realita dapat meningkatkan kedisiplinan pada siswa kelas IX.6SMP Negeri 9 Pekanbaru tahun pelajaran 2020/2021. Hasil observasi kedisiplinan siswa sebelum penerapan konseling realita adalah kategori rendah. Padasiklus I hasil observasi kedisiplinan siswa adalah kategori sedang. Padasiklus II hasil observasi kedisiplinan siswa adalah kategori tinggi
Orientasi Masa Depan Mahasiswa Yang Mengalami Prokrastinasi Akademik Saat Menyusun Skripsi
Authors: Tiara Nur Aziza , Susanti Reni 
Published: April 2022

AbstrakOrientasi masa depan merupakan variabel yang dapat mempengaruhi prokrastinasi akademik pada mahasiswa yang sedang mengerjakan skripsi. Penelitian ini merupakan penelitian korelasional yang bertujuan untuk melihat bagaimana hubungan antara orientasi masa depan dengan prokrastinasi akademik pada mahasiswa. Penelitian ini merupakan penelitian kuantitatif korelasional denggan alat pengumpulan data berupa skala orientasi masa depan disusun berdasarkan teori Nurmi (1991) dan skala prokrastinasi akademik disusun berdasarkan teori Ferrari dkk (1995). Subjek penelitian adalah mahasiswa Fakultas Sain dan Teknologi UIN Suska Riau. Teknik pengambilan sampel penelitian menggunakan non probability sampling, dimana pengambilan sampel memberikan peluang yang sama bagi mewakili populasi untuk dipilih menjadi sampel penelitian dengan jumlah sampel 141. Metode pengumpulan data menggunakan skala psikologi yaitu skala orientasi masa depan dan skala prokrastinasi akademik. Hipotesis yang diajukan adalah terdapat hubungan negatif antara orientasi masa depan dengan prokrastinasi akademik pada mahasiswa. Berdasarkan hasil analisis korelasi product moment dari pearson’s hipotesis diterima terdapat hubungan yang signifikan artinya semakin tinggi orientasi masa depan maka semakin rendah orientasi masa depan pada mahasiswa dan semakin rendah orientasi masa depan maka semakin tinggi prokrastinasi akademik.Kata kunci: Orientasi masa depan; prokrastinasi akademik
Revisiting Feminist Strategies in Poetry: Gender, Genre, and Power Relation
Authors: Mulyani A.B. Sri 
Published: April 2022

The patriarchal gender division of private-public dichotomy assigned to particular gender for different roles and sphere is generally viewed as an “ancient” practice in the West. However, this “ancient” gender conception that can be traced from its Greco-Roman and Judeo-Christian roots can frequently be pertinently visible in modern Western world as exemplified in the notion of “Woman’s place” and; it becomes the dominant gender discourse. Consequently, this discourse continually creates hierarchical and unequal power relation that marginalizes women in accessing education and their full participation in public spheres. This limited accessibility to education (including language and literacy) also shapes the roles and status of women as writers in Western critical and literary tradition. Writing as a profession is traditionally men’s domain; therefore, the production and contribution of women writers have less privilege and space in the Western canon. Women writers from time to time have to struggle to reclaim their rights and place in it. This research attempts to re-examine how this (re)production of the binary opposition of private-public sphere operates in language and literature of the Western critical literary tradition by scrutinizing the selected poems by the selected women writers in this research. Furthermore, this research also studies and locates how women writers employ particular strategies in gendering and degendering their writings as both aesthetic and ideological expressions. In conclusion, this research argues that women writings are not “deficient” and “inferior” to their male counterpart; and instead their status and difference as writers are the result of patriarchal dominance and power relation that historically have subordinated and denied them equal public access to education, language, literacy, and literary production.