bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of financial institutions on exchanges in the agricultural commodity supply chain: An information economics perspective
Authors: Darby Jessica L. , Miller Jason W. , Williams Brent D. , McKenzie Andrew M. 
Published: June 2022

AbstractRecent advances in supply chain research point to the vital but often overlooked role of financial institutions, such as banks and financial markets, in the execution of supply chain activities. We extend this incipient research stream by drawing on information economics and Penrose's resource‐based view of the firm to theorize about how financial markets act as a source of information and influence exchange activities in the agricultural commodity supply chain. We test our hypotheses in the U.S. agricultural commodities context, specifically the U.S. rice industry, using a novel data set that combines financial market data with proprietary data on exchanges between farmers and customers. Time series econometric analyses reveal that information from financial markets influences exchanges between farmers and customers, but it has asymmetric effects depending on exchange dynamics and local market conditions. Overall, our analyses support our hypotheses and advance supply chain research by building theory about market‐based exchange dynamics and by broadening the scope of mechanisms through which financial institutions impact exchange activities. For practice, we offer quantitative insights that can be leveraged by farmers and purchasing managers. For policymakers, we offer timely guidance related to the provision of information and the ‘real’ implications of financial markets.
Simple renal cyst as an independent risk factor for hypertension
Authors: Zhou Yaqing , Jia Limei , Lu Baojin , Bai Long , Cui Wei 
Published: June 2022

AbstractA simple renal cyst (SRC) may increase the risk for hypertension. The authors examined the relationship between a SRC and hypertension in participants receiving physical examinations at Hebei Medical University. This study enrolled 66 883 participants who received physical examinations at our center from January 2012 to December 2017. Demographic data, medical history related to hypertension, hematological indexes, hypertension, and SRC subtype based on ultrasound examinations were examined. The relationship between SRC and hypertension was analyzed using univariate and multivariate logistic regression analysis in different models. Subgroup analysis and propensity score (PS) matching were also performed. Based on SRC subtype (unitary vs. multiple, small vs. large, unilateral vs. bilateral), a comprehensive scoring system was established to determine the effect of SRC load on hypertension. The results of univariate and multivariate analysis indicated that SRC was a risk factor for hypertension (P < .01). Subgroup and interaction analysis showed the homogeneity that SRC was an independent risk factor for hypertension in multiple subgroups (P > .05). A SRC remained an independent risk factor for hypertension after PS matching (P < .01). Based on a scoring system that considered different SRC subtypes, the risk for hypertension increased with renal cyst load (P < .01). In conclusions, a SRC was an independent risk factor for hypertension, and there was a positive correlation between SRC load and hypertension. The risk of hypertension increased gradually with the size, number, and location of a SRC. Careful follow‐up or excision should be considered for patients with SRCs.
PBRM1 deficiency oncogenic addiction is associated with activated AKT–mTOR signalling and aerobic glycolysis in clear cell renal cell carcinoma cells
Authors: Tang Yu , Jin Yan‐Hong , Li Hu‐Li , Xin Hui , Chen Jin‐Dong , Li Xue‐Ying , Pan You‐Fu 
Published: June 2022

AbstractThe PBRM1 (PB1) gene which encodes the specific subunit BAF180 of the PBAF SWI/SNF complex, is highly mutated (~ 40%) in clear cell renal cell carcinoma (ccRCC). However, its functions and impact on cell signalling are still not fully understood. Aerobic glycolysis, also known as the ‘Warburg Effect’, is a hallmark of cancer, whether PB1 is involved in this metabolic shift in clear cell renal cell carcinoma remains unclear. Here, with established stable knockdown PB1 cell lines, we performed functional assays to access the effects on 786‐O and SN12C cells. Based on the RNA‐seq data, we selected some genes encoding key glycolytic enzymes, including PFKP, ENO1, PKM and LDHA, and examined the expression levels. The AKT–mTOR signalling pathway activity and expression of HIF1α were also analysed. Our data demonstrate that PB1 deficiency promotes the proliferation, migration, Xenograft growth of 786‐O and SN12C cells. Notably, knockdown of PB1 activates AKT–mTOR signalling and increases the expression of key glycolytic enzymes at both mRNA and protein levels. Furthermore, we provide evidence that deficient PB1 and hypoxic conditions exert a synergistic effect on HIF 1α expression and lactate production. Thus, our study provides novel insights into the roles of tumour suppressor PB1 and suggests that the AKT–mTOR signalling pathway, as well as glycolysis, is a potential drug target for ccRCC patients with deficient PB1.
Performance of three Trichogramma species as biocontrol agents on Spodoptera frugiperda eggs
Authors: Yang Lei , Li Fen , Lü Xin , Xing Binglin , Pan Xiao , Shi Xueyan , Li Jun , Wu Shaoying 
Published: June 2022

AbstractSpodoptera frugiperda (JE Smith) (Lepidoptera: Noctuidae) is one of the most polyphagous and migratory pests posing a great threat to crops. The Trichogramma species (Hymenoptera: Trichogrammatidae) play an important role in dampening pest oscillations. In this study, we examined the performance of three egg parasitoids, T. chilonis, T. dendrolimi and T. pretiosum, to control S. frugiperda. Indoor experiments indicated significant differences in fecundity and female proportion between T. chilonis, T. dendrolimi and T. pretiosum. However, no significant differences were observed in developmental duration and female parasitic capacity. Field trials were carried out to clarify their control efficiency. Results showed that the parasitism rates of three parasitoids ranged from 10.7% to 31.4%, without significant differences. Moreover, field release of parasitoids resulted in significant decreases in damage rate (the ratio of infested plants) and damage index. A positive correlation was revealed between temperature (14.5–24.5 °C) and parasitism rate of T. chilonis. In contrast, the relative humidity (66% ~ 77%) did not affect their performance. Taken together, all three Trichogramma species can be used as potential agents to control S. frugiperda, which undoubtedly lays a solid foundation for their application.
Influence of bone morphology on the mechanobiological stimuli distribution of maxillary anterior labial bone: A biomechanical study
Authors: Liao Menglin , Wang Chunjuan , Wang Chao , Xu Yamei 
Published: June 2022

AbstractObjectiveThis study intended to ascertain the dimensional effects of labial bone thickness and height on the mechanobiological stimuli distribution of maxillary anterior labial bone through biomechanical analysis.Material and methodsTwelve 3D finite element models of an anterior maxillary region with an implant were computer‐simulated, including four levels of labial bone thicknesses (2, 1.5, 1.0, and 0.5 mm) and three levels of labial bone heights (normal, reduced by 1/3, reduced by 1/2). A 45° buccolingual oblique load of 100 N was applied to the implant restoration.ResultsEquivalent stress and principal strain mainly concentrated on crestal bone around the implant neck. The maximum equivalent stress in bone decreased as labial bone mass decreased, while the maximum principal strain and the displacement of dental implant increased as labial bone mass decreased. No significant difference of these three indicators was observed, when the labial bone thickness changed in the range of 2.0–1.0 mm with sufficient labial bone height.ConclusionsIn terms of biomechanics, the thickness of labial bone plate was recommended ≥1 mm. Sufficient labial bone height was warranted to prevent the stability of the implants from being seriously affected. The labial bone heights were more effective than thicknesses on the mechanobiological stimuli response of the dental implant‐bone system.Clinical significanceFor this 3D finite element study, the biomechanical responses under different bone mass conditions were explored, in order to predict the process of bone remodeling and provide valid clinical recommendations for the decision‐making process regarding the choices of tissue augmentation for some specific esthetic implantation cases for future clinical applications.
Effects of virtual reality on preoperative anxiety in children: A systematic review and meta‐analysis of randomised controlled trials
Authors: Chen Yen‐Ju , Wang Cheng‐Ju , Chen Chi‐Wen 
Published: June 2022

AbstractAimsTo synthesise and evaluate the effectiveness of virtual reality interventions in preoperative children.BackgroundChildren consider operations as a predictable threat and stressful event. Children's anxiety before an operation increases as the time draws closer. Children could understand the operating room environment and process before the operation using virtual reality, which may reduce their anxiety before an operation.DesignA systematic review and meta‐analysis of randomised controlled trials following the Cochrane method were conducted.MethodCINAHL, Cochrane Library, Embase, Joanna Briggs Institute, MEDLINE and PubMed databases were searched for randomised controlled trials published before February 2021. A random‐effects model meta‐analysis to calculate pooled prevalence and 95% confidence intervals was performed. Conduction of the review adheres to the PRISMA checklist.ResultsOf 257 articles screened, six interventions involving 529 participants aged 4–12 years were included in the analysis. All study evidence levels were B2/Level 2, the quality was medium to high on the modified Jadad scale, with a low risk of bias. The results revealed that virtual reality significantly reduced preoperative anxiety in children (SMD: −0.91, 95% CI: −1.43 to −0.39, p = .0006). Furthermore, virtual reality significantly improved children's compliance with anaesthesia (SMD: 3.49, 95% CI: 1.32 to 9.21, p = .01).ConclusionChildren who used virtual reality before an operation felt more familiar with the operating room environment and understood the preoperative preparation procedures. Virtual reality effectively reduced children's anxiety and improved their compliance with anaesthesia.Relevance to clinical practiceThis systematic review and meta‐analysis investigated the effect of virtual reality on preoperative anxiety in children and the findings supported its positive effects. The results could provide a reference for incorporating virtual reality into preoperative preparation guidelines.
Genotypes analysis of Candida albicans species complex from healthy individual saliva in Ahvaz, Iran
Authors: Kianifar S. , Rezaei-Matehkolaei A. , Zarei-Mahmoudabadi A. 
Published: June 2022

Abstract
Although Candida albicans is a part of the mycoflora of healthy individuals, it is causing mild to severe forms of candidiasis in patients with underlying diseases. The recent molecular investigations were classified three genotypes, A, B and C for C. albicans. The aim of the present study was to detect different genotypes of C. albicans complex species in a normal population in Iran. Saliva was randomly collected from a normal population, homogenized and cultured on CHROMagar Candida. Classical and molecular methods were used for the detection of isolates. Candida 25S rDNA gene was amplified using the primer pairs of CA-INT-L and CA-INT-R for ABC genotyping of C. albicans. Candida albicans complex was recovered from 103/194 (53·1%) normal papulation. Genotype A with a frequency of 41·7% was the most common isolate, followed by genotype C (34%), genotype B (20·4%) and genotype D (3·9%). Genotyping of C. albicans species complex from healthy individuals showed the presence of three A, B and C genotypes of C. albicans and one D genotype of C. dubliniensis.
CO2‐induced biochemical changes in leaf volatiles decreased fire‐intensity in the run‐up to the Triassic–Jurassic boundary
Authors: Baker Sarah J. , Dewhirst Rebecca A. , McElwain Jennifer C. , Haworth Matthew , Belcher Claire M. 
Published: June 2022

Summary

The Triassic–Jurassic boundary marks the third largest mass extinction event in the Phanerozoic, characterized by a rise in CO2‐concentrations from c. 600 ppm to c. 2100–2400 ppm, coupled with a c. 3.0–4.0°C temperature rise. This is hypothesized to have induced major floral turnover, altering vegetation structure, composition and leaf morphology, which in turn are hypothesized to have driven changes in wildfire. However, the effects of elevated CO2 on fuel properties, such as chemical composition of leaves, are also important in influencing fire behaviour, but yet have not been considered.

We test this by selecting three Triassic analogue species grown experimentally in different atmospheric compositions, and analyse variations in leaf chemistry, and leaf level flammability. These data were used to inform a fire behaviour model.

We find that all three species tested showed a reduction in their volatile component, leading to lower flammability. Accounting for these variations in a model, our results suggest that leaf intrinsic flammability has a measurable impact on modelled fire behaviour.

If scaled up to ecosystem level, periods of elevated CO2 may therefore be capable of inducing both biochemical and morphological changes in fuel properties, and thus may be capable of influencing fire behaviour.
Unique and redundant functions of cytoplasmic actins and nonmuscle myosin II isoforms at epithelial junctions
Authors: Ivanov Andrei I. , Lechuga Susana , Marino‐Melendez Armando , Naydenov Nayden G. 
Published: June 2022

AbstractThe integrity and functions of epithelial barriers depend on the formation of adherens junctions (AJs) and tight junctions (TJs). A characteristic feature of AJs and TJs is their association with the cortical cytoskeleton composed of actin filaments and nonmuscle myosin II (NM‐II) motors. Mechanical forces generated by the actomyosin cytoskeleton are essential for junctional assembly, stability, and remodeling. Epithelial cells express two different actin proteins and three NM‐II isoforms, all known to be associated with AJs and TJs. Despite their structural similarity, different actin and NM‐II isoforms have distinct biochemical properties, cellular distribution, and functions. The diversity of epithelial actins and myosin motors could be essential for the regulation of different steps of junctional formation, maturation, and disassembly. This review focuses on the roles of actin and NM‐II isoforms in controlling the integrity and barrier properties of various epithelia. We discuss the effects of the depletion of individual actin isoforms and NM‐II motors on the assembly and barrier function of AJs and TJs in model epithelial monolayers in vitro. We also describe the functional consequences of either total or tissue‐specific gene knockout of different actins and NM‐II motors, with a focus on the development and integrity of different epithelia in vivo.
Are Women Doing It for Themselves? Female Managers and the Gender Wage Gap*
Authors: Theodoropoulos Nikolaos , Forth John , Bryson Alex 
Published: June 2022

ABSTRACTUsing linked employer‐employee data for Britain, we find a robust association between the share of female managers in the workplace and the size of the gender wage gap. In workplace fixed‐effects estimates, the gap is eradicated when more than 60% of workplace managers are women, a scenario that obtains in around one fifth of all workplaces. The association between the share of female managers and the gender wage gap is more pronounced when workplace managers set pay at the workplace, and where employees are paid for performance. These findings are consistent with the proposition that women are more likely to be paid equitably when managers have discretion in the way they set pay or reward performance and those managers are women. They suggest that a stronger presence of women in managerial positions can help tackle the gender wage gap.
De novo transcriptome sequencing of Capsicum frutescens. L and comprehensive analysis of salt stress alleviating mechanism by Bacillus atrophaeusWU‐9
Authors: Wang Wenfei , He Yanhui , Wu Zhansheng , Li Tao , Xu Xiaolin , Liu Xiaochen 
Published: June 2022

AbstractSalt stress, as one of the most severe environmental stresses, can cause a series of changes in plants. However, the explanation of plant salt stress alleviating mechanism of plant growth–promoting rhizobacteria (PGPR) was hindered by the limited availability of transcriptomic information for salt stress‐treated plants grown in a microorganism‐controlled environment. Our previous reports have selected Bacillus atrophaeus WU‐9 as PGPR significantly alleviating pepper (Capsicum frutescens. L) salt stress. In this work, the RNA‐seq analysis of salt stress‐treated and untreated plants, grown with and without WU‐9 in a microorganism‐controlled environment, was used to reveal the plant salt stress alleviating mechanisms of WU‐9. Twelve sequencing libraries, prepared by treating with WU‐9 and salt (150 mM NaCl for 36 h), were constructed by RNA‐Seq technique. Non‐inoculated seedlings mainly respond to salt stress through regulation of signal transduction, such as ethylene‐activated signaling pathway, signaling and cell communication, etc. And ethylene signal participated in salt stress response in pepper through regulating defense responses, fruit ripening and senescence. WU‐9 inoculation under salt stress mainly improves salt tolerance and plant growth by regulating salt stress‐responding ethylene and auxin signal transduction, utilization of proline, photosynthesis, antioxidant enzyme activities and cell enlargement. Furthermore, 86 differentially expressed genes and 20 transcription factors were identified as associated with salt stress response and tolerance. Thus, this innovative transcriptomic study identified the salt stress response and alleviation in C. frutescens. L with PGPR inoculation. This result provided novel insights into the salinity alleviation in pepper regulated by PGPR.
Parents' pension eligibility and migrant consumption in urban China: Evidence from a quasi‐experiment
Authors: He Yuke , Niu Geng , Zhao Guochang 
Published: June 2022

AbstractThis article analyzes data from the 2009 and 2014 waves of the Survey on Rural Urban Migration in China (RUMiC) to investigate the impact of parents' pension status on migrants' consumption in cities. Exploiting the introduction of the new rural pension scheme (NRPS), we perform a difference‐in‐differences (DID) analysis. We find that having a parent in a rural area that is pension eligible increases migrants' consumption level by 9.4%. However, this effect is constrained to survival consumption. Furthermore, the positive impact of parents' pension eligibility is more pronounced for migrants who earn a lower income, receive less education, suffer from poorer health, have stronger economic ties with their parents, and have a parent in poorer health. Our results suggest that improving rural social welfare has a spillover effect on urban consumption.
A chromosome‐level genome of Syringa oblata provides new insights into chromosome formation in Oleaceae and evolutionary history of lilacs
Authors: Wang Yi , Lu Limin , Li Jingrui , Li Huayang , You Yichen , Zang Shuying , Zhang Yongqing , Ye Jianfei , Lv Zemin , Zhang Zhaoyu , Qin Yongsheng , Zhang Hongling , Xia Fei , Li Hui , Zhang Huijin , Fan Peige , Shi Lei , Liang Zhenchang , Cui Hongxia 
Published: June 2022

SUMMARYLilacs (Syringa L.), a group of well‐known ornamental and aromatic woody plants, have long been used for gardening, essential oils and medicine purposes in East Asia and Europe. The lack of knowledge about the complete genome of Syringa not only hampers effort to better understand its evolutionary history, but also prevents genome‐based functional gene mining that can help in the variety improvement and medicine development. Here, a chromosome‐level genome of Syringa oblata is presented, which has a size of 1.12 Gb including 53 944 protein coding genes. Synteny analysis revealed that a recent duplication event and parallel evolution of two subgenomes formed the current karyotype. Evolutionary analysis, transcriptomics and metabolic profiling showed that segment and tandem duplications contributed to scent formation in the woody aromatic species. Moreover, phylogenetic analysis indicated that S. oblata shared a common ancestor with Osmanthus fragrans and Olea europaea approximately 27.61 million years ago (Mya). Biogeographic reconstruction based on a resequenced data set of 26 species suggested that Syringa originated in the northern part of East Asia during the Miocene (approximately 14.73 Mya) and that the five Syringa groups initially formed before the Late Miocene (approximately 9.97 Mya). Furthermore, multidirectional dispersals accompanied by gene introgression among Syringa species from Northern China during the Miocene were detected by biogeographic reconstruction. Taken together, the results showed that complex gene introgression, which occurred during speciation history, greatly contributed to Syringa diversity.
B vitamin supply in plants and humans: the importance of vitamer homeostasis
Authors: Liu Zeguang , Farkas Peter , Wang Kai , Kohli Morgan‐Océane , Fitzpatrick Teresa B. 
Published: June 2022

SUMMARYB vitamins are a group of water‐soluble micronutrients that are required in all life forms. With the lack of biosynthetic pathways, humans depend on dietary uptake of these compounds, either directly or indirectly, from plant sources. B vitamins are frequently given little consideration beyond their role as enzyme accessory factors and are assumed not to limit metabolism. However, it should be recognized that each individual B vitamin is a family of compounds (vitamers), the regulation of which has dedicated pathways. Moreover, it is becoming increasingly evident that individual family members have physiological relevance and should not be sidelined. Here, we elaborate on the known forms of vitamins B1, B6 and B9, their distinct functions and importance to metabolism, in both human and plant health, and highlight the relevance of vitamer homeostasis. Research on B vitamin metabolism over the past several years indicates that not only the total level of vitamins but also the oft‐neglected homeostasis of the various vitamers of each B vitamin is essential to human and plant health. We briefly discuss the potential of plant biology studies in supporting human health regarding these B vitamins as essential micronutrients. Based on the findings of the past few years we conclude that research should focus on the significance of vitamer homeostasis – at the organ, tissue and subcellular levels – which could improve the health of not only humans but also plants, benefiting from cross‐disciplinary approaches and novel technologies.
Educar por medio del arte en una escuela multicultural
Authors: Álvarez-Valdivia Ibis Marlene , Morón-Velasco Mar 
Published: June 2022

Este artículo ilustra las oportunidades que ofrece el aprendizaje por medio del arte para vincular el patrimonio cultural del alumnado de origen inmigrado a los objetivos del currículum. Se siguió un modelo de investigación-acción educativa en la que participaron futuros docentes durante las prácticas en escuelas de educación primaria en Cataluña (España), en las que prevalece una composición social desfavorecida. Los resultados aportan una metodología interdisciplinar e inclusiva de educación mediante las artes, que promueve el desarrollo de competencias fundamentales para el aprendizaje. Se sugieren ideas para incluir la propuesta en la formación inicial docente.