bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ki67 Index Correlates with Tumoral Volumetry, and 5-ALA Compromised Resection Margins in Glioblastoma
Authors: Sprenger Flávia , Junior Erasmo Barros da Silva , Ramina Ricardo , Cavalcanti Marcella Santos , Martins Samuel Botter , Cerqueira Matheus Abrantes , Falcão Alexandre Xavier , Teixeira Bernardo Corrêa de Almeida 
Published: September 2022

Abstract
Background: Malignant gliomas are the most prevalent primary cerebral tumor. Preoperative imaging plays an important role, and the prognosis is closely related to surgical resection and histomolecular aspects. Our goal was to correlate Ki67 indexes with tumoral volumetry in semiautomatic segmentation on preoperative magnetic resonance images in a 5-ALA assisted resection cohort.
Methods: We included initially seventy-eight IDH-wildtype glioblastoma patients with complete preoperative imaging submitted to 5-ALA assisted resections. Clinical, surgical, and histomolecular findings were also obtained. Preoperative magnetic resonance studies were preprocessed and segmented semiautomatically on VISVA for whole tumor (WT) on 3D FLAIR, enhancing tumor (ET), and necrotic core (NC) on 3D post-gadolinium T1. Edema volumes (ED) were obtained from the subtraction of ET and NC from WT. According to previous studies, we used a 20% cutoff for Ki67 for statistical analysis.
Results: Final sample was of 48 patients. Higher Ki-67 indexes correlated positively with higher WT (p = 0,01), ET (p = 0,03) and ED volumes (p = 0,04), with no correlation with NC volumes (p = 0,18). Ki67 indexes were also higher in 5-ALA compromised margins (p = 0,01).
Conclusions: There is a correlation between Ki67, the metabolically active tumoral volumes, and 5-ALA compromised margins. Tumoral volumetry aspects (WT, ET, and ED), except for NC, correlated directly with Ki67 indexes. Methodological inconsistencies are probably responsible for contradictory literature findings, and further studies are needed to validate and reproduce these findings.
Does the Timing of Appendectomy Affect Outcomes and Postoperative Complications?
Authors: Berenguer María San Basilio , Delgado-Miguel Carlos , Ramírez-Amorós Carla , Sarmiento María , Lapeña Lucas Moratilla , Almeyda Arturo , Mejía Ricardo , Martínez Leopoldo 
Published: September 2022

Abstract
Purpose: There is controversy about the necessity of nighttime appendectomy. The aim of this study was to determine whether timing of appendectomy performance plays a role on postoperative complications.
Methods: A retrospective single-center comparative study was performed in children who underwent surgery for acute appendicitis between 2017-2021. Patients were divided into groups based on the time slot in which surgery was performed: morning (8:00h-15:00h), afternoon (15:00h-22:00h) and night (22:00h-08:00h). Demographics, intraoperative data, length of hospital stay and postoperative complications were analyzed and compared.
Results: A total of 1643 patients were included: 337 were operated in the morning, 751 in the afternoon and 555 at night. We found no demographic differences. When comparing the intraoperative data, no differences were observed in the percentage of complicated appendicitis. Night group patients presented a higher percentage of open appendectomies (64.5%) when compared to afternoon (49.6%) and morning (46.2%) groups (p<0.001). Surgery time was also significantly shorter in the night group (45.2min ± 18,9min) (p<0.001). There were no differences in length of hospital stay, postoperative complications rate or readmission rate.
Conclusion: These results show that in our institution time slot in which the appendectomy is performed has no consequences in postoperative outcomes and complications.
Investigation on Air-Blast Explosion Effect on reinforced concrete Buildings (Case Study)
Authors: Mohamed Faiza , Al-Rawi Zauba A. Aziz , Sayed Ahmed El-Badawy , Barahim Abubaker M. Omer , Tawfic Yasser R. 
Published: September 2022

Abstract
As a result of the spread of wars and terrorist acts that led to the bombing of public and private buildings in Aden/Yemen which is a case study, in this research it became necessary to conduct an assessment of the type of damage, and study the possibility of rehabilitating the elements that were partially destroyed. Here; in this paper, we studied of a number of buildings that were subjected to a direct air explosion, assessed the blast force effect of the wave on the surrounding buildings, found that the damage is directly related to the distance to the center of the explosion, as well as the age of the building and the materials used, which give us indications to recognize the factors that help to assess and treat the damage.
Through this study, it was concluded that there is a need to the compressed gas produced from the explosion to be released by hatches in the closed areas in the building. If these hatches affect the function of these areas, weak points must be made in the walls, which it will act as an exit paths for the blast wave emitted from the source, and help the wave transit throughout the area causing less damages in the concrete structure.
Optimization of A2O Process by Changing Anoxic Tank Volume Based on GPS-X Simulation
Authors: Lei Shuhan , Zhao Jianqiang , Zhao Junkai , Xie Shuting , Zhang Ju , Shi Bingfeng 
Published: September 2022

Abstract
In order to improve the nitrogen removal efficiency of the anaerobic-anoxic-aerobic process (A2O), the effect of anoxic tank volume on the total nitrogen (TN) removal efficiency and total phosphorus (TP) removal efficiency were investigated under different ratios of chemical oxygen demand (COD) to nitrogen (C/N). The results showed that under C/N=7, the HRT of anoxic tank increased from 1.8 h to 3.6 h had little effects on the removal efficiency of COD, but largely improving the removal efficiency of TN and TP which increased from 66.8% and 93.8% to72.0% and 95.2%, respectively. Under C/N=10, increasing the volume of the anoxic tank did not significantly improve the removal efficiency of COD, TN and TP. The optimal HRTs of anoxic tank and the corresponding volume ratios of anaerobic, anoxic and aerobic were 4.0 h, 4.3 h and 1:2.5:6.75, 1:2.69:6.75 simulated by GPS-X software under C/N=7 and C/N=10, respectively. The results proposed that the appropriate elevated the volume of the anoxic tank could help A2O process to meet the TN discharge concentration lower than 15 mg/L. Under low C/N, changing the HRT of anoxic tank to improve the pollutant removal efficiency of A2O reactor was more significantly, so this method was more suitable for the case of insufficient carbon source.
Enzyme activities and gene expression in digestion and metabolism of Hyriopsis cumingii under different temperature and diet ration
Authors: Sun Yu , Liu Yang , Li Yanhong , Yao Weizhi , Wu Zhengli 
Published: September 2022

Abstract
The traditional culture method of Hyriopsis cumingii is in urgent need of transformation, industrial aquaculture is a sustainable cultivation mode, and the control of environmental conditions and food is the basis and key. To evaluate combined effects of rations (high-ration, medium-ration, and low-ration) and temperatures (13 ± 0.2℃, 23 ± 0.2℃ and 33 ± 0.2℃) on digestion and metabolism of H. cumingii, a 3 × 3 factor comprehensive test was established. Levels of digestive enzymes like amylase (AMS), lipase (LPS), cellulase (CL), metabolic enzymes like glutamic pyruvate transaminase (GPT), glutamic oxaloacetate transaminase (GOT), pyruvate kinase (PK), hexokinase (HK), and metabolism-related genes like carnitine palmitoyltransferase-1 (CPT1), low-density lipoprotein receptor (LDLR) of mussels were analyzed during 21 days. Results showed levels of digestive and metabolic indicators remained stable in the medium-ration × 23℃ treatment, and were significantly (P < 0.05) higher than others on day 21. When exposed to low-ration, high-ration, 13℃ or 33℃, these biochemical indicators rose briefly and then significantly (P < 0.05) declined. Results suggested the medium-ration and 23℃ were the best diet quantity and temperature for H. cumingii. Short-term thermal, cold, semi-starving, and overfeeding treatments induced metabolic levels of mussels to meet the energy demand of anti-oxidative stress. However, long-term stress resulted in liver injury of H. cumingii, reduced the digestive and metabolic efficiency of the mussel, and affected its growth performance and health. This study has practical significance in exploring culture environment and feeding conditions, controlling breeding cost, and increasing the growth and yield in industrial aquaculture.
High-mobility magnetic two-dimensional electron gas in engineered oxide interfaces
Authors: Yang Ruishu , Gao Yuqiang , Wang Shuanhu , Jin Kexin 
Published: September 2022

Abstract
The engineered interfaces of complex oxides have abundant physical properties and provide a powerful platform for the exploration of fundamental physics and emergent phenomena. In particular, research on the two-dimensional magnetic systems with high mobility remains a long-standing challenge for the discovery of quantum phase and spintronic applications. Here, we introduce a few atomic layers of delta doping layer at LaAlO3/SrTiO3 interfaces through elaborately-controllable epitaxial growth of SrRuO3. After inserting a SrRuO3buffer layer, the interfaces exhibit a well-defined anomalous Hall effect up to 100 K and their mobility is enhanced by 3 orders of magnitude at low temperatures. More intriguingly, a large unsaturated positive magnetoresistance is created at interfaces. Combining with the density functional theory calculation, we attribute our findings to the electron transfer at interfaces and the magnetic moment of Ru4+ 4dbands. The results pave a way for further research of two-dimensional ferromagnetism and quantum transport in all-oxide systems.
Curative effect of unilateral double channel spinal endoscopy and endoscopic decompression in the treatment of lumbar spinal stenosis:a meta-analysis
Authors: Lv Shuangwen , Xia Xiansheng 
Published: September 2022

Abstract
Background
The efficacy of unilateral dual-channel spinal endoscopy (UBE) and microscopic endoscopic decompression (MED) in the treatment of lumbar spinal stenosis (LSS) was compared by Meta-analysis.
Method
PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), and Wanfang Database were searched by computer for all studies on the treatment of LSS with UBE and MED from the establishment of the database to January 2021. Authors, year of publication, study design, subject characteristics, sample size, surgical protocol, age, sex ratio, duration of surgery, length of hospital stay, complications, visual analogue scale (VAS), and Oswestry Disability Index (ODI) were obtained. The operation time, hospital stay, complication rate, waist and lower extremity VAS score and ODI before operation, early postoperative period and last follow-up were analyzed by Revman 5.3 software.
Result
Finally, 7 articles were included, including 6 articles in English and 1 article in Chinese; 2 articles were randomized controlled studies, and 5 articles were case-control studies. There were 251 patients in the UBE group and 224 patients in the microscopy group. Compared with the MED group, the UBE group had a shorter hospital stay (MD=-2.28, 95% CI: -3.42~-1.14, P < 0.001), and a lower VAS score for early postoperative low back pain (MD=-0.80, 95%CI) : -1.44~-0.16, P = 0.01), the difference was statistically significant. There were no significant differences in operation time, complication rate, waist VAS score before operation and at last follow-up, lower extremity VAS score, ODI, and dural expansion area before operation, early after operation and at last follow-up between the two groups ( P > 0.05).
Conclusion
Compared with MED, UBE has better early low back pain relief and hospital stay after LSS, but there is no significant difference in long-term efficacy and safety.
The concept of softness is structurally similar in memory, haptics, and vision
Authors: Cavdan Müge , Goktepe Nedim , Drewing Knut , Doerschner Katja 
Published: September 2022

Abstract
Humans are very accurate and robust at recognizing materials (e.g., linen or hand cream) and estimating their properties (e.g., softness or stickiness). To achieve this, they rely on sensory input as well as on previous knowledge and experience. Softness is an important mechanical material property that can be perceived directly through haptic-, but also indirectly through visual inspection. While visual and haptic softness are similar we have found in previous work that there are also differences in how softness related material attributes are judged. Here, we investigate how softness memory relates to haptic and visual perceptual spaces of softness. We performed an online experiment where people rated different sensory aspects of soft materials, for which only names were presented, i.e., without any haptic or visual information about the material. We compared results with previous studies where identical ratings were made on the basis of visual and haptic information. Correlation and Procrustes analyses show that the description spaces for all materials were similar for verbal, haptic, and visual presentation. However, linear discriminant classifiers also unveiled subtle differences in how soft materials are represented and predicted from different types of information. Specifically, we found that memory better predicted visual than haptic softness.
Impact of COVID-19 pandemic on the worldwide burden of tinnitus
Authors: Nocini Riccardo , Lippi Giuseppe , Mattiuzzi Camilla 
Published: September 2022

Abstract
Background: This infodemiological analysis is aimed to define whether the worldwide burden of tinnitus may have increased during the coronavirus disease 2019 (COVID-19) pandemic.
Methods. We performed an electronic search in Google Trends with the term tinnitus as “medical topic”, setting the geographical area to “worldwide”, within a search period comprising the past 5 years (i.e., from August 2017 to August 2022).
Results: A significant increase has been observed in the median worldwide burden of Google searches for tinnitus by comparing the volume after (median, 64; IQR, 60-69) versus before (58; IQR 52-61; p<0.001; +10.3%) the initiation of the COVID-19 pandemic. Although such trend was consistent over time irrespective of the virus variants, with values of Google searches always higher than the pre-COVID period (all p<0.001), higher weekly Google Trends searches were noted during prevalence of Delta and Omicron lineages.
Conclusion: Specific interventions shall be planned to support the larger number of patients that may seek healthcare consultation and/or may need to live with tinnitus after the COVID-19 pandemic.
Treatment of distal humeral shaft fractures with metaphyseal locking compression plate through the posterior midline approach
Authors: Huang Xiuxi , Fang Kaibin , Dai Zhangsheng , Lin Xiaocong 
Published: September 2022

Abstract
Objective: To investigate the feasibility of treating distal humeral shaft fractures with metaphyseal locking compression plate(MLCP) fixation through the posterior midline approach．
Methods: From january2005 to january2021, patients with humeral fractures who underwent surgical treatment in a large class III a hospital were selected as the research subjects. The operation time, intraoperative blood loss, fracture healing, complications and elbow function of the two groups were compared.
Result: A total of 125 patients were included in the study, of which 72 patients were included in the observer and 53 patients were included in the control group. These patients were followed up for at least one year.There was no significant difference between the two groups in general information, including age, sex, fracture type and so on.The observation group had advantages in operation time, intraoperative bleeding, average fracture healing time and complications. There was no significant difference in myao score between the two groups.
Conclusion: The use of metaphyseal locking compression plates for fixation of fractures of the middle and lower humerus through the posterior median approach should be considered. This approach has the advantages of short operation time, short fracture healing time and less complications.
Amplification of Annual and Diurnal Cycles of Alpine Lightning
Authors: Simon Thorsten , Mayr Georg J. , Morgenstern Deborah , Umlauf Nikolaus , Zeileis Achim 
Published: September 2022

Abstract
The response of lightning to a changing climate is not fully understood. Historic trends of proxies known for fostering convective environments suggest an increase of lightning over large parts of Europe. Since lightning results from the interaction of processes on many scales, as many of these processes as possible must be considered for a comprehensive answer. Recent achievements of decade-long seamless lightning measurements and hourly reanalyses of atmospheric conditions including cloud micro-physics combined with flexible regression techniques have made a reliable reconstruction of lightning down to its seasonally varying diurnal cycle feasible. The European Eastern Alps and their surroundings are chosen as reconstruction region since this domain includes a large variety of land-cover, topographical and atmospheric circulation conditions. The most intense changes over the last four decades occurred over the high Alps where lightning activity doubled in the past decade compared to the 1980s. There, the lightning season reaches a higher maximum and starts one month earlier. Diurnally, the peak is up to 50% stronger with more lightning strikes in the afternoon and evening hours. Signals along the southern and northern alpine rim are similar but weaker whereas the flatlands surrounding the Alps have no significant trend.
Lowbush Blueberry Notes
Authors: Abdalla Dennis A. 
Published: September 2022

Abstract
Maine Industry Now I.Q.F.: Maine’s lowbush blueberry industry now freezes 70% of its total crop, which averages 25 to 26 million pounds per year. Most of this fruit is frozen in ultramodern I.Q.F. (Individually Quick Frozen) freezers. Tunnel(belt)-type and flo-freeze type I.Q.F. units are now in operation supplying the baking industry with cleaner and more uniform fruit. I.Q.F. blueberries are loose when packaged and easily incorporated into the baked product. Standard package containers include the 20 pound tin, 30 pound poly-lined paper box and 60 nound poly-lined multi-walled paper bag. Presently there are three tunneltype and two flo-freeze type I.Q.F. units in operation solely for lowbush blueberries in Maine.
Effects of N-Dimethyl Amino Succinamic Acid on Quality of Cortland Apples
Authors: Shutak V. G. , Kitchin J. T. , Dayawon M. M. 
Published: September 2022

Abstract
Color and firmness of Cortland apples were improved and storage scald greatly reduced by spraying trees at certain times during the 1964 growing season with N-dimethyl amino succinamic acid (also known as B-995 and more recently as Alar 50°) at the rate of 5,000 ppm. Sprays in early and mid-summer reduced fruit size, however, and late season sprays were not as effective in preventing scald.
Influence of N-Dimethyl Amino Succinamic Acid on Fruit Yield of Once-Over Harvested Tomatoes1
Authors: Bergman Ernest L. 
Published: September 2022

Abstract
At present the use of machinery for harvesting tomatoes is increasing. However, no tomato variety or cultivar is available for once-over harvesting that produces yield and qualitv satisfactory to both growers and processors. It was felt that with the use of a growth retardant such as Alar2, applied as a spray, even ripening could be induced so that commercial acceptable present-day cultivars might be used as a stopgap for machine harvesting until better tomato cultivars are developed.
Stimulation of Leaf Abscission of Woody Plants by Potassium Iodide and Alanine1
Authors: Larsen Fenton E. 
Published: September 2022

Abstract
Nurserymen often wish to dig plants prior to natwl leaf abscission. Plants for some areas could be shipped for fall planting if digging could be done early enough. In other areas an extended digging period would lessen harvest pressure or make better use of labor. Early digging would also de crease danger of losses from early fall freezes. Some plants (i.e. Weigela) retain their leaves extremely late in the season
Water Movement in Stems of American Holly at Low Temperatures
Authors: Winslow A. C. , Havis J. R. 
Published: September 2022

Abstract
Studies on winter desiccation of broadleaved evergreens have raised the question of low temperature impedance of water movement in roots and stems. Temperature control of a section of stem can be readily accomplished by the use of cooling collars. Johnson (3), Handley (1), and Zimmerman (6) have brought about wilting of the leaves of various tree species by cooling parts of the stem to near or below the tissue freezing point. Presumably, the wilting was caused by restriction of water flow through the cooled section of stems. The wilted foliage recovered after the stem temperatures were allowed to rise, but no attempt has been reported to measure the minimum temperature at which water started to flow through the stem after freezing. To obtain information on this latter question was the primary objective of the study reported here.
The Seasonal Sales Problem of a Garden Center,1
Authors: Padgett J. H. , Pokorn F. A. 
Published: September 2022

Abstract
Seasonal demand for nursery products is a major problem encountered by garden center owners throughout the country. The problem is not unique to the garden center business, but one finds that many businesses have seasonal demands for their products and/or services. A solution to this particular business situation for garden centers would certainly increase business profits.
No-till Popcorn Performs as well as Conventionally Grown Popcorn
Authors: Knavel Dean E. , Herron J. W. , White Gerald M. 
Published: September 2022

Abstract
A two-year study of popcorn cultivars grown by no-tillage (NT) and conventional tillage (CT) systems indicated that popcorn can be produced successfully by NT. Plant populations, plant heights, ear lengths, and ear weights were generally greater for NT than for CT. Popping expansion of NT corn, except for ‘Snow Puff’, a white kernel cultivar, was equal to that of CT. The use of either NH4NO3 or Ca(NO3)2 at 56 kg N/ha in 1981 and 84 kg N/ha from NH4NO3 in 1982 produced the highest yields. Increasing N to 140 kg/ha decreased yields of ‘Snow Puff’ in CT. The N levels had no effect on popping quality.
In Vitro Plantlet Production from Young Capitulum Explants of Gerbera jamesonii
Authors: Laliberté S. , Chrétien L. , Vieth J. 
Published: September 2022

Abstract
Two clones of Gerbera jamesonii were propagated in vitro from fragments of young capitulum, 0.5 to 0.7 cm in diameter. These were cut into 20 to 25 explants and placed on several media. Media containing 0.57 μm (0.1 mg/liter) indole-3-acetic acid (IAA) and 4.4 or 8.8 μm (1 or 2 mg/liter) 6-benzylaminopurine (BA) gave best shoot production. Three mineral solutions were tested. All shoots over 0.5 cm rooted regardless of the IAA level in the medium.
In Vivo Pollen Germination of Aglaonema Affected by Relative Humidity
Authors: Henny R J 
Published: September 2022

Abstract
Abstract. Aglaonema crispum (Pitcher & manda) Nicols., A. pictum (Roxb.) Kunth and A. commutatum Schott ‘Treubii’ inflorescences pollinated at high (100%) relative humidity (RH) showed excellent in vivo pollen germination. Inflorescences pollinated at low (40% to 50%) RH revealed significantly less germination than those pollinated at high RH. Pollen exposed to low RH for 4 hr before pollination did not germinate.