bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between liver fat content and lifestyle factors in adults with metabolic syndrome
Authors: Laine Saara , Sjöros Tanja , Garthwaite Taru , Saarenhovi Maria , Kallio Petri , Löyttyniemi Eliisa , Vähä-Ypyä Henri , Sievänen Harri , Vasankari Tommi , Laitinen Kirsi , Houttu Noora , Saukko Ekaterina , Knuuti Juhani , Saunavaara Virva , Heinonen Ilkka H. A. 
Published: October 2022

AbstractThe aim of this study was to investigate the associations between liver fat content (LFC), sedentary behaviour (SB), physical activity (PA), fitness, diet, body composition, and cardiometabolic risk factors in adults with metabolic syndrome. A total of 44 sedentary adults (mean age 58 [SD 7] years; 25 women) with overweight or obesity participated. LFC was assessed with magnetic resonance spectroscopy and imaging, SB and PA with hip-worn accelerometers (26 [SD 3] days), fitness by maximal bicycle ergometry, body composition by air displacement plethysmography and nutrient intake by 4-day food diaries. LFC was not independently associated with SB, PA or fitness. Adjusted for sex and age, LFC was associated with body fat%, body mass index, waist circumference, triglycerides, alanine aminotransferase, and with insulin resistance markers. There was and inverse association between LFC and daily protein intake, which persisted after further adjusment with body fat%. LFC is positively associated with body adiposity and cardiometabolic risk factors, and inversely with daily protein intake. SB, habitual PA or fitness are not independent modulators of LFC. However, as PA is an essential component of healthy lifestyle, it may contribute to liver health indirectly through its effects on body composition in adults with metabolic syndrome.
Factors which impact the length of hospitalisation and death rate of COVID-19 patients based on initial triage using capillary blood gas tests: a single centre study
Authors: Ilczak Tomasz , Micor Alicja , Waksmańska Wioletta , Bobiński Rafał , Kawecki Marek 
Published: October 2022

AbstractAn important element in the effective treatment of patients infected with the SARS-CoV-2 virus during the pandemic is an effective early triage to determine patient allocation and in-patient therapy. This paper assesses the prognostic value of capillary blood gas tests in predicting extended hospitalisation and death due to COVID-19. This retrospective statistical research is based on a group of 200 patients, hospitalised from 15 October 2020 to 08 March 2021. The study utilised the treatment documentation of these patients hospitalised due to COVID-19 at the Pulmonology and Thoracic Surgery Centre in Bystra (Southern Poland) during this period. The hospital has 50 beds with access to oxygen for COVID-19 patients and a five-bed intensive care unit. On the basis of the obtained results, conclusions were drawn that the need for early oxygen therapy with an oxygen mask and low pH values in capillary blood are significant risk factors for prolonging hospitalisation due to COVID-19. Age, the need for early oxygen mask therapy and low oxygen saturation are important risk factors for death from COVID-19. Capillary blood gas analysis is a simple and effective method of early in-patient segregation of COVID-19 patients.
Unconventional pairing in few-fermion systems at finite temperature
Authors: Pęcak Daniel , Sowiński Tomasz 
Published: October 2022

AbstractAttractively interacting two-component mixtures of fermionic particles confined in a one-dimensional harmonic trap are investigated. Properties of balanced and imbalanced systems are systematically explored with the exact diagonalization approach, focusing on the finite-temperature effects. Using single- and two-particle density distributions, specific non-classical pairing correlations are analyzed in terms of the noise correlations—quantity directly accessible in state-of-the-art experiments with ultra-cold atoms. It is shown that along with increasing temperature, any imbalanced system hosting Fulde–Ferrel–Larkin–Ovchinnikov pairs crossovers to a standard Bardeen-Cooper-Schrieffer one characterized by zero net momentum of resulting pairs. By performing calculations for systems with different imbalances, the approximate boundary between the two phases on a phase diagram is determined.
Efficacy of a local anesthetic gel infusion kit for pain relief after minimally invasive colorectal surgery: an open-label, randomized clinical trial
Authors: Shin Jung Kyong , Jeong Heejoon , Lee Woo Yong , Yun Seong Hyeon , Cho Yong Beom , Huh Jung Wook , Park Yoon Ah , Sim Woo Seog , Kim Hee Cheol 
Published: October 2022

AbstractContinuous wound infusion with local anesthesia is an effective method for reducing postoperative pain after laparoscopic colorectal surgery. However, most subcutaneous local anesthesia is delivered through continuous injection, which can be inconvenient for patients. This study compared the effectiveness of postoperative pain relief from the application of a local poloxamer 407-based ropivacaine hydrogel (Gel) to the incision site with continuous infusion-type ropivacaine administration (On-Q) in patients undergoing laparoscopic colorectal surgery. This prospective, randomized, non-inferiority study included 61 patients who underwent laparoscopic colorectal surgery with an incision length of 3–6 cm. All 61 patients were randomly assigned to the Gel group (poloxamer 407-based 0.75% ropivacaine, 22.5 mg) or the On-Q group (0.2% ropivacaine, 4 mg/hour for two days). Postoperative analgesia was induced in all patients with intravenous patient-controlled analgesia (IV-PCA). The outcome measures, which were assessed for 72 h after surgery, included the total amount of fentanyl consumed via IV-PCA (primary endpoint), and the amount of rescue analgesia (pethidine) and postoperative pain intensity assessed using a numeric rating scale (NRS) [secondary endpoints]. The Gel was administered to 31 patients and On-Q was used for 30 patients. There was no significant difference in the total usage of fentanyl between the two groups (Gel group, 1623.98 mcg; On-Q group, 1595.12 mcg; P = 0.806). There was also no significant difference in the frequency of analgesic rescue medication use (P = 0.213) or NRS scores (postoperative 6 h, P = 0.860; 24 h, P = 0.333; 48 h, P = 0.168; and 72 h, P = 0.655) between the two groups. The Gel, which continuously delivers a local anesthetic to operative sites, can thus be considered an effective device for analgesia and pain relief for midline incisions in laparoscopic colorectal surgery.
Coupling strategy between high-index and mid-index micro-metric waveguides for O-band applications
Authors: Skandalos Ilias , Domínguez Bucio Thalía , Mastronardi Lorenzo , Rutirawut Teerapat , Gardes Frederic Y. 
Published: October 2022

AbstractThe integration of fast and power efficient electro-absorption modulators on silicon is of utmost importance for a wide range of applications. To date, Franz-Keldysh modulators formed of bulk Ge or GeSi have been widely adopted due to the simplicity of integration required by the modulation scheme. Nevertheless, to obtain operation for a wider range of wavelengths (O to C band) a thick stack of Ge/GeSi layers forming quantum wells is required, leading to a dramatic increase in the complexity linked to sub-micron waveguide coupling. In this work, we present a proof-of-concept integration between micro-metric waveguides, through the butt-coupling of a $${1.25}\,{\upmu \hbox {m}}$$

1.25

μ
m

thick N-rich silicon nitride (SiN) waveguide with a $${1.25}\,{\upmu \hbox {m}}$$

1.25

μ
m

thick silicon waveguide for O-band operation. A numerical analysis is conducted for the design of the waveguide-to-waveguide interface, with the aim to minimize the power coupling loss and back-reflection levels. The theoretical results are compared to the measured data, demonstrating a coupling loss level of $${0.5}\,\hbox {dB}$$

0.5

dB

for TE and TM polarisation. Based on the SiN-SOI interconnection simulation strategy, the simulation results of a quantum-confined Stark effect (QCSE) stack waveguide coupled to a SiN waveguide are then presented.
Mesenchymal stem cell bioenergetics and apoptosis are associated with risk for bronchopulmonary dysplasia in extremely low birth weight infants
Authors: Hazra Snehashis , Li Rui , Vamesu Bianca M. , Jilling Tamas , Ballinger Scott W. , Ambalavanan Namasivayam , Kandasamy Jegen 
Published: October 2022

AbstractOxidant stress contributes significantly to the pathogenesis of bronchopulmonary dysplasia (BPD) in extremely low birth weight (ELBW) infants. Mitochondrial function regulates oxidant stress responses as well as pluripotency and regenerative ability of mesenchymal stem cells (MSCs) which are critical mediators of lung development. This study was conducted to test whether differences in endogenous MSC mitochondrial bioenergetics, proliferation and survival are associated with BPD risk in ELBW infants. Umbilical cord-derived MSCs of ELBW infants who later died or developed moderate/severe BPD had lower oxygen consumption and aconitase activity but higher extracellular acidification—indicative of mitochondrial dysfunction and increased oxidant stress—when compared to MSCs from infants who survived with no/mild BPD. Hyperoxia-exposed MSCs from infants who died or developed moderate/severe BPD also had lower PINK1 expression but higher TOM20 expression and numbers of mitochondria/cell, indicating that these cells had decreased mitophagy. Finally, these MSCs were also noted to proliferate at lower rates but undergo more apoptosis in cell cultures when compared to MSCs from infants who survived with no/mild BPD. These results indicate that mitochondrial bioenergetic dysfunction and mitophagy deficit induced by oxidant stress may lead to depletion of the endogenous MSC pool and subsequent disruption of lung development in ELBW infants at increased risk for BPD.
Investigation of the effect of fly ash content on the bonding performance of CFRP-concrete interface in sulfate environment
Authors: Liu Shengwei , Li Qi , Zhang Jiawei , Bai Chengyu , Zhao Kun , Jin Gaoming 
Published: October 2022

AbstractThe present study focuses on the investigation of the interfacial bond behavior of carbon fiber-reinforced polymer (CFRP)-concrete under dry–wet sulfate cycles by double-sided shear testing. Besides, the effects of fly ash content on the interfacial failure characteristics, interfacial debonding bearing capacity, CFRP strain distribution, and interfacial shear stress peak were analyzed. The interfacial debonding capacity, maximum CFRP strain, and peak value of interfacial shear stress of the CFRP-concrete interface decreased with increasing erosion time under the sulfate dry–wet cycle's action, according to the sulfate dry–wet cycle test results. The sulfate resistance of the CFRP-concrete interface increased after the addition of fly ash. However, the final decrease amplitude of interfacial debonding capacity, CFRP maximum strain, and maximum interfacial shear stress all reduced as the fly ash content increased. The effective bond length of the interface gradually increased with increasing erosion time; however, the change in fly ash content had little effect on the effective bond length, and the final effective bond length of the samples with different fly ash content was the same. Moreover, the CFRP-concrete interfacial bearing capacity model under the sulfate dry–wet cycle was established by introducing sulfate's comprehensive influence coefficient and considering fly ash content's influence. In conclusion, the comparative analysis of the prediction model and test results revealed that the prediction model could well reflect the degradation law of interfacial debonding bearing capacity with sulfate attack time.
Fatty acyl-CoA reductase influences wax biosynthesis in the cotton mealybug, Phenacoccus solenopsis Tinsley
Authors: Tong Haojie , Wang Yuan , Wang Shuping , Omar Mohamed A. A. , Li Zicheng , Li Zihao , Ding Simin , Ao Yan , Wang Ying , Li Fei , Jiang Mingxing 
Published: October 2022

AbstractMealybugs are highly aggressive to a diversity of plants. The waxy layer covering the outermost part of the integument is an important protective defense of these pests. However, the molecular mechanisms underlying wax biosynthesis in mealybugs remain largely unknown. Here, we analyzed multi-omics data on wax biosynthesis by the cotton mealybug, Phenacoccus solenopsis Tinsley, and found that a fatty acyl-CoA reductase (PsFAR) gene, which was highly expressed in the fat bodies of female mealybugs, contributed to wax biosynthesis by regulating the production of the dominant chemical components of wax, cuticular hydrocarbons (CHCs). RNA interference (RNAi) against PsFAR by dsRNA microinjection and allowing mealybugs to feed on transgenic tobacco expressing target dsRNA resulted in a reduction of CHC contents in the waxy layer, and an increase in mealybug mortality under desiccation and deltamethrin treatments. In conclusion, PsFAR plays crucial roles in the wax biosynthesis of mealybugs, thereby contributing to their adaptation to water loss and insecticide stress.
Gas-phase fragmentation of single heteroatom-incorporated Co5MS8(PEt3)6+ (M = Mn, Fe, Co, Ni) nanoclusters
Authors: Gholipour-Ranjbar Habib , Deepika  , Jena Puru , Laskin Julia 
Published: October 2022

AbstractFunctionalization of metal-chalcogenide clusters by either replacing core atoms or by tuning the ligand is a powerful technique to tailor their properties. Central to this approach is understanding the competition between the strength of the metal-ligand and metal-metal interactions. Here, using collision-induced dissociation of atomically precise metal sulfide nanoclusters, Co5MS8L6+ (L = PEt3, M = Mn, Fe, Co, Ni) and Co5-xFexS8L6+ (x = 1–3), we study the effect of a heteroatom incorporation on the core-ligand interactions and relative stability towards fragmentation. Sequential ligand loss is the dominant dissociation pathway that competes with ligand sulfide (LS) loss. Because the ligands are attached to metal atoms, LS loss is an unusual dissociation pathway, indicating significant rearrangement of the core prior to fragmentation. Both experiments and theoretical calculations indicate the reduced stability of Co5MnS8L6+ and Co5FeS8L6+ towards the first ligand loss in comparison with their Co6S8L6+ and Co5NiS8L6+ counterparts and provide insights into the core-ligand interaction.
Spherical hydroxyapatite nanoparticle scaffolds for reduced lead release from damaged perovskite solar cells
Authors: Mokhtar Muhamad Z. , Altujjar Amal , Wang Bing , Chen Qian , Ke Jack Chun-Ren , Cai Rongsheng , Zibouche Nourdine , Spencer Ben F. , Jacobs Janet , Thomas Andrew G. , Hall David , Haigh Sarah J. , Lewis David J. , Curry Richard , Islam M. Saiful , Saunders Brian R. 
Published: October 2022

AbstractPerovskite solar cells continue to attract interest due to their facile preparation and high power conversion efficiencies. However, the highest efficiency perovskite solar cells inevitably contain lead, which raises concerns over contamination of drinking water when a solar module is broken and then flooded. We previously showed that conventional synthetic hydroxyapatite (HAP) nanoparticles could capture some of the lead from broken solar cells, but the amount of lead released was well above the safe drinking water level. Here, we modify the HAP synthesis to prepare new spherical-HAP (s-HAP) nanoparticles with a 60% increase in the Pb absorption capacity. We blend s-HAPs with TiO2 nanoparticles to construct mixed scaffolds and investigate their effect on (FAPbI3)0.97(MAPbBr3)0.03 solar cell performance and lead capture. Replacement of 80% of the TiO2 nanoparticles with s-HAP causes the power conversion efficiency to increase from 18.61% to 20.32% as a result of decreased charge carrier recombination. Lead contamination of water from devices subjected to simulated hail damage followed by flooding is shown to decrease exponentially with increasing s-HAP content. The lead concentration in water after 24 h is below the US safe water drinking limit.
Lexical Alignment and Communicative Success in Autism Spectrum Disorder
Authors: Stabile Mackenzie , Eigsti Inge-Marie 
Published: October 2022

Purpose:
Typical speakers tend to adopt words used by their conversational partners. This “lexical alignment” enhances communication by reducing ambiguity and promoting a shared understanding of the topic under discussion. Lexical alignment has been little studied to date in autism spectrum disorder (ASD); furthermore, it has been studied primarily via structured laboratory tasks that may overestimate performance. This study examined lexical alignment in ASD during discourse and explored associations with communicative success and executive function.

Method:
Thirty-one autistic and nonautistic adolescents were paired with a study-naïve research assistant (RA) to complete a social communication task that involved taking turns verbally instructing (guiding) the partner to navigate on a map. Lexical alignment was operationalized as the proportion of shared vocabulary produced by guides on successive maps. Task accuracy was operationalized as the pixels contained within the intended and drawn routes.

Results:

Results indicated that autistic adolescents had greater difficulty describing navigational routes to RAs, yielding paths that were less accurate. Alignment was reduced in autistic participants, and it was associated with path accuracy for nonautistic, but not autistic, adolescents. The association between lexical alignment and executive function missed significance (
p
= .05); if significant, the association would indicate that greater executive function difficulty was associated with reduced lexical alignment.

Conclusions:
These findings provide preliminary evidence of reduced lexical alignment in ASD in an unstructured discourse context. Moreover, positive associations between lexical alignment and task performance in the neurotypical group raise the possibility that interventions to promote the use of shared vocabulary might support better communication.

Supplemental Material:

https://doi.org/10.23641/asha.21313719
Screening Vietnamese Children in the United States for Autism Risk: Examination of the Modified Checklist for Autism in Toddlers–Revision With Follow-Up Vietnamese
Authors: Seung HyeKyeung , Bui Jamie , Pham San 
Published: October 2022

Purpose:
This study examined the utility of the Vietnamese version of the Modified Checklist for Autism in Toddlers–Revised with Follow-Up (M-CHAT-R/F) for screening Vietnamese children for autism risk. Cultural reasons and/or limited access to health care has resulted in delays in receiving an autism diagnosis for children of racial minorities. Delays in receiving an autism diagnosis may subsequently result in delay in receiving early intervention services. Therefore, this study examined the feasibility of implementing autism screening for Vietnamese American children.

Method:
The M-CHAT-R/F is a well-validated autism screening test offered in multiple languages such as Vietnamese. It takes approximately 10 min for caregivers to complete 20 yes/no-response items and includes a follow-up interview for initial screen-failed items to reduce false-positive rates. We recruited 205 parents of children aged between 16 and 36 months in Southern California to conduct a broadband screening, not an autism-specific screening. The participants responded to a print or an online Qualtrics version of the M-CHAT-R/F in a language of their choice, either English or Vietnamese.

Results:
A total of 79 of the 205 participants provided complete responses. Of the 79 participants, 20% of the results were initially screened positive. Seven participants were not available for follow-up interviews. Screen-positive rates were estimated to range from 8% to 15% based on completed follow-ups.

Conclusions:
The estimated screen-positive rates in this exploratory study were higher than the reported screen-positive rates in a Vietnamese population sample using the Modified Checklist for Autism in Toddlers. Limitations of this study include participant recruitment difficulty, a small sample size, and the inability to conduct follow-up interviews with some participants. Future studies should use larger and more representative samples and examine potential cultural factors possibly impacting interest in screening Vietnamese children for autism risk.
Quality‐enabled decentralized dynamic IoT platform with scalable resources integration
Authors: Bhola Biswaranjan , Kumar Raghvendra , Rani Preeti , Sharma Rohit , Mohammed Mazin Abed , Yadav Kusum , Alotaibi Shoayee Dlaim , Alkwai Lulwah M. 
Published: October 2022

AbstractThe Internet of Things (IoT) are standard inter connected devices aimed at join everyday object to the internet. This ecosystem include manufacturing, agriculture, smart cities, industry, as well as healthcare. The capacity of controlling and monitoring the objects of the physical world using IoT generate numerous opportunities. However some extra cost is also added to make the device globally accessible. The aggressive growth of the IoT devices, the multifariousness of IoT network technology, and the diversity of IoT use cases generate a question mark regarding the sustainability of the IoT. The aim of the proposed work to contribute in this regard, for that a dynamic integration of IoT objects that is pre determined for (i) creating an IoT platform dynamically (ii) monitoring the current status of IoT environment (iii) measuring the quality of the overall system (iv) helping to utilize all the interconnected efficiently by adding M2M communication, is introduced. Some property set which is suitable for decentralized IoT platform is also explained. Such types of dynamic IoT platform helps in every IoT application domain including industrial IoT. With the propound research, the aim is to create a dynamic IoT platform to simplify the production of next generation. The primary contribution of the proposed paper is a concept which can help to design IoT device in a faster way, which can be called rapid hardware development approach. Efficiently used human resources, that means any one having common technical knowledge can design the device, and reduce the hardware heterogeneous architecture.
Deep absorption in SDSS J110511.15+530806.5
Authors: Marculewicz Marcin , Nikolajuk Marek , Różańska Agata 
Published: October 2022

Aims. We study the origin of the anomalous deep absorption in a spectrum of the SDSS J110511.15+530806.5 distant quasar (z = 1.929) obtained by the Sloan Digital Sky Survey in Data Release 14 of the optical catalog. We aim to estimate the velocity of absorbing material, and we show that this material considerably affects our measurements of the black hole (BH) mass in massive quasars with the use of common virial mass estimators.
Methods. The spectral shape of the quasar was modeled assuming that the accretion disk emission is influenced by a hot corona, warm skin, and absorbing material located close to the nucleus. The whole analysis was undertaken with XSPEC models and tools. The overall spectral shape was represented with the AGNSED model, while the deep absorption is well described by two Gaussians.
Results. The observed spectrum and the fitting procedure allowed us to estimate the BH mass in the quasar as 3.52 ± 0.01 × 109 M⊙, the nonzero BH spin is a* = 0.32 ± 0.04, and the accretion rate is ṁ = 0.274 ± 0.001. The velocities of the detected absorbers lie in the range of 6330–108 135 km s−1. When we consider that absorption is caused by the C IV ion, one absorber is folding toward the nucleus with a velocity of 73 887 km s−1. We derived a BI index of about 20 300 km s−1 and a mass outflow rate up to 38.5% of the source accretion rate.
Conclusions. The high absorption observed in SDSS J110511.15+530806.5 is evidence of fast winds that place the source in the group of objects on the border with UFO (ultra-fast outflows), strong broad absorption line, and fast failed radiatively accelerated dusty outflow (FRADO). This absorption affects the BH mass measurement by two orders of magnitude as compared to virial mass estimation.