bluuebunny/crossref_metadata_2025_split huggingface dataset:
Occupational therapy treatment of complex regional pain syndrome in children and adolescents: a scoping review protocol
Authors: Rider John V. , Tay Monica C. , De Armond Megan 
Published: August 2022

Objective:
This scoping review will explore the literature related to occupational therapy interventions and delivery methods for pediatric complex regional pain syndrome.

Introduction:
Complex regional pain syndrome is a debilitating pain condition that is becoming increasingly diagnosed within the pediatric population. Untreated, it can negatively impact a child’s occupational engagement and participation, social functioning, and family dynamics. A multidisciplinary treatment approach is typically recommended, with occupational therapy as an essential component. Occupational therapy interventions for pediatric complex regional pain syndrome usually promote a child’s ability to participate in daily activities to prevent further impairment and disability. Despite evidence that occupational therapy practitioners treat this population, no review has been conducted of the available literature on occupational therapy interventions for pediatric complex regional pain syndrome.

Inclusion criteria:
This review will consider studies that include any form of occupational therapy interventions for participants with complex regional pain syndrome who are 18 years or younger. Quantitative, qualitative, and observational studies, and text and opinion papers will be considered.

Methods:
The JBI methodology will be used to conduct this scoping review. MEDLINE, Embase, Scopus, APA PsycINFO, CINAHL, OTDBASE, OT Search (AOTA), OTseeker, and ProQuest Dissertations and Theses Global will be searched for studies in English, with no limit on publication date. Two independent reviewers will screen the titles, abstracts, and full texts of the selected studies. Data collection will be performed using a tool developed by the researchers based on the standardized JBI tool. Data will be presented in a comprehensive narrative summary.
Women's experiences of maternity waiting homes in sub-Saharan Africa: a qualitative systematic review protocol
Authors: Yarinbab Teklemariam Ergat , Harrison Margo Shawn , Belachew Tefera 
Published: August 2022

ABSTRACT

Objective:
The objective of this review is to synthesize women's experiences related to the use of maternity waiting homes in sub-Saharan Africa.

Introduction:
Most maternal deaths occur within resource-limited settings. Sub-Saharan Africa and Southern Asia account for around 86% of all maternal deaths worldwide, with sub-Saharan Africa alone contributing roughly two-thirds of all maternal deaths. The long distances that women must travel to reach health facilities has been highlighted as the main cause of maternal death. Maternity waiting homes have been recognized as a strategy to enhance maternal health outcomes by bringing women living in geographically isolated locations closer to health facilities. However, maternity waiting home utilization rates are low and vary across different settings.

Inclusion criteria:
The study population will be women (15 to 49 years of age) living in sub-Saharan Africa who have experiences related to maternity waiting home use. This may include experiences with service provisions during the final weeks of pregnancy and 2 weeks after childbirth. Stays of at least 1 day will be considered for inclusion.

Methods:
Databases including MEDLINE, Web of Science, Scopus, and Hinari will be searched. Gray literature sources will include Google Scholar and MedNar. Studies published in English from January 2000 onward will be included. Two independent reviewers will screen the titles and abstracts, followed by an examination of full-text papers. Any disagreements will be handled through discussion or consultation with a third reviewer. Two reviewers will independently assess the methodological quality of included studies and extract the data. The articles will be meta-aggregated and presented in tabular or narrative format.

Systematic review registration number:
PROSPERO CRD42022306003
Automatically Landing an Unmanned Aerial Vehicle Using Perspective-n-Point Algorithm Based on Known Runway Image: Area Localization and Feature Enhancement With Time Consumption Reduction
Authors: Kongkaew Sakol , Ruchanurucks Miti , Takamatsu Jun 
Published: August 2022

Abstract
This research proposes a method to track a known runway image to land an unmanned aerial vehicle (UAV) automatically by finding a perspective transform between the known image and an input image in real-time. Apparently, it improves the efficiency of feature detectors in real-time, so they can better respond to perspective transformation and reduce the processing time. A UAV is an aircraft that is controlled without a human pilot on board. The flight of a UAV operates with various degrees of autonomy, either autonomously using computational-limited on-board computers or under remote control by a human operator. UAVs were originally applied for missions where human access was not readily available or where it was dangerous for humans to go. Nowadays, the most important problem in monitoring by an autopilot is that the conventional system using only the GPS sensors provides inaccurate geographical positioning. Therefore, controlling the UAV to take off from or land on a runway needs professional input which is a scarce resource. The characteristics of the newly developed method proposed in this paper are: (1) using a lightweight feature detector, such as SIFT or SURF, and (2) using the perspective transformation to reduce the effect of affine transformation that results in the feature detector becoming more tolerant to perspective transformation. In addition, the method is also capable of roughly localizing the same template in consecutive frames. Thus, it limits the calculation area that feature matching needs to work on.
Self-Excited Second-Order Azimuthal Thermoacoustic Instabilities in an Annular Combustor With Oblique-Injecting Swirling Burners
Authors: Fang Yuanqi , Wang Gaofeng , Lyu Zengyi 
Published: August 2022

Abstract
In this paper, we experimentally investigate the thermoacoustic instability issue in an annular combustor with 16 oblique-injecting premixed swirling burners. It is demonstrated that there exist three dominant modes in a narrow operating range: a Helmholtz mode, a first-order azimuthal mode, and a second-order azimuthal mode. Their modal frequencies are consistent with the simulating prediction of a Helmholtz solver. Our present investigations are more focused on the second-order azimuthal modes which are comparatively infrequently observed in the experiments of model annular combustors. The dynamic mode decomposition approach is used to postprocess the high-speed flame images, revealing the primary dynamic structure of the flame responses for the three self-excited thermoacoustic modes. A pressure field analyzing ansatz has been involved to feature the self-excited azimuthal instabilities, including their dynamical nature (standing, spinning, or mixed) and the time-varying pressure antinodes. Results indicate that the first-order and second-order azimuthal modes both exhibit a standing nature with relatively fixed pressure antinodes. Additionally, in a transition case where these two azimuthal modes co-exist, the first-order azimuthal mode behaves as a weakly oscillating standing mode whose pressure antinodes exhibit a fat-tailed distribution. Exceptionally, the second-order azimuthal mode is split into a pair of nondegenerate modes with two close frequencies. And the split pairs are found to yield distinct pressure antinodes that are orthogonal to each other.
Microtomography of Soil and Soot Deposits: Analysis of Three-Dimensional Structures and Surface Morphology
Authors: Suman Alessio , Vulpio Alessandro , Pinelli Michele , D'Amico Lorenzo 
Published: August 2022

Abstract
The detrimental effects generated by the gas turbine fouling phenomenon are well known. Due to soil and soot particles ingestion, gas turbines experience performance drops related to greater fuel consumption and even lower efficiency. These effects are related to the modification of the shape and surface roughness of relevant surfaces (compressor and turbine blades and vanes, especially) due to the presence of a thin layer generated by micro/nanosized particle adhesion. Such contaminants are swallowed by the unit and, as a function of the operating conditions, adhere to the surface, causing a sort of dangerous coating to the surface. In this work, a microtomography analysis of the deposited layer is reported. The deposited layer has been generated using microsized soil and soot powders under specific impact conditions and substrate surface roughness similar to those in the cold section of a gas turbine compressor. The microtomography analysis has been carried out using the beamline at the ELETTRA Sincrotrone research center. Thanks to the resolution of the beamline, the detection of the three-dimensional internal structure of the soil and soot layers have revealed that within the layer, the structure is characterized by discontinuities. Soot and soil particles, even characterized by similar diameter distributions and test conditions, generate layer structures that differ by the magnitude, orientation, location of the internal discontinuities, and surface morphology (i.e., roughness). The comprehension of the packing process allows us to understand the adhesion process and define general guidelines to predict the fouling phenomenon.
Approximating Gas Turbine Combustor Exit Temperature Distribution Factors Using Spatially Under-Sampled Measurements
Authors: Lou Fangyuan 
Published: August 2022

Abstract
In gas turbine engines, the temperature field at the exit plane of the combustor is highly unsteady and complex, with large radial and circumferential variations. The circumferential temperature variations (hot-streaks) are caused by the discrete nature of fuel and dilution air jets, and combustor lining coolant flow results in a strong radial temperature gradient. Two widely adopted parameters include the radial temperature distribution factor (RTDF) and the overall temperature distribution factor (OTDF) to quantify combustor exit temperature nonuniformity. The state-of-the-art approach to characterizing the combustor exit temperature nonuniformity is to carry out an extensive traverse along the circumferential direction at a spatial resolution of two to three degrees. With hundreds of measurements in place, the combustor OTDF and RTDF can be obtained. Though the approach is practical, this involves the design of complex traverse mechanisms and can be costly. To address this challenge, this paper presents a novel method for predicting combustor exit TDFs using much sparser measurements. The approach's effectiveness was examined using three engine representative combustor exit temperature measurements covering a single-burner, double-burner, and entire annulus. In all cases, the hot-streaks-related features are well resolved in the reconstructed temperature field, and the multiwavelet approximation method yields almost identical RTDF to experiment with majority variations of less than 1.0% using sparse measurements. In addition, the method's robustness was examined, and considerations for the implementation of the method were provided.
Numerical Investigation of Supersonic Air-to-Air Ejectors Including Design Effects on Entrainment Efficiency
Authors: Sicuro Bruno Henrique Bogado , Malatesta Vinícius , Papa Ramon 
Published: August 2022

Abstract
The objective of this work is to develop and validate a computational fluid dynamics (CFD) model of a supersonic air ejector, a device largely used in aircraft, and to determine how its efficiency behaves when some of its geometric parameters vary, fully exploring the physical phenomena of the problem. It is important to highlight that in the aeronautical industry the competitiveness of any device intrinsically relies on its efficiency, such that a CFD model for an ejector is indispensable for proper design. This paper presents a study of several turbulence models Rk–ε en, Rk–ε std, k–ω shear stress transport (SST), Spalart–Allmaras (SA), and generalized k–ω (GEKO). A validation process was conducted by comparing CFD results with two supersonic air ejector experiments. The turbulence model was also validated with these experiments, and it was concluded that the k–ω GEKO model is able to reproduce the physics of the supersonic air ejector problem with greater fidelity than traditional turbulence models in terms of entrainment ratio, with a 6% relative error reduction in relation to the traditional k–ω SST model, which has been considered by multiple authors as the best Reynolds-averaged Navier–Stokes (RANS) approach in ejector's CFD studies. After this validation process, the sensitivity of ejector efficiency to two geometric parameters was evaluated: the nozzle exit position and the ejector mixing chamber height.
Supplemental Material: Quantifying controls on the occurrence of nonmarine fossils
Authors: Regan Anik K. , al. et 
Published: August 2022

<p>Data files and R scripts needed to generate the graphs seen in Figures 3 and 4: ‘fossilCounts.csv’ contains data used to calculate the probability of occurrence; ‘probabilityOfOccurrenceFunctions.txt’ contains the R code for helper functions used in figure creation; ‘probabilityOfOccurrenceGraphs.txt’ contains the R code workflow used for calculations and for generating Figures 3 and 4. </p>
062 Ictal asystole during a generalised seizure following a photoparoxysmal response
Authors: Gilligan Michael , Mooney Sean , O’Riordan Sean , Connolly Sean 
Published: August 2022

BackgroundIctal asystole is the transient cessation of cardiac electrical activity during an epileptic seizure. It has been described in association with focal seizures, most often arising from the left temporal lobe in patients with refractory epilepsy.Case and Results of InvestigationsA 31-year-old right-handed male had a first generalised seizure at work following a period of increased alcohol consumption and sleep deprivation. There was no family history of epilepsy and neurological examination was normal. Generalised sharpened discharges with polyspikes occurred in an EEG two days later. A second EEG performed three months later contained a photopar- oxysmal response followed by a generalised seizure accompanied by a 7.5-second period of asystole. Electrographically the seizure was generalised in onset, without lateralising features, although the clinical semiology was notable for some initial focal features. MRI brain did not reveal any focal abnormality. The patient was commenced on levetiracetam and has remained seizure-free since.DiscussionThis is a rare case of ictal asystole in a patient with a generalised-onset seizure, and probable underlying primary generalised epilepsy.
070 Real-world experience of perampanel monotherapy in epilepsy patients with focal-onset and generalised-onset seizures
Authors: Alsaadi Taoufik , Toledo Manuel , Loro Fernando Ayuga , Trinka Eugen , Wu Tony , Malhotra Manoj , Ngo Leock Y , Gil-Nagel Antonio , Villanueva Vicente 
Published: August 2022

Data from 44 pooled clinical practice studies were compared for epilepsy patients with focal-onset and/or generalised-onset seizures treated with perampanel (PER) monotherapy (n=268) (first-line or conversion to monotherapy). Retention was assessed after 3, 6 and 12 months of PER treatment. Seizure freedom rates and responder rates (≥50% seizure frequency reduction), assessed by seizure type at last visit were evaluated (last observation carried forward). Adverse events (AEs) and discontinuation due to AEs were evaluated. Seizure types at baseline were focal-onset only (75.0%), generalised-onset only (24.5%), and focal-onset and generalised-onset (0.5%). At 3, 6 and 12 months, retention rates were 91.1%, 87.3% and 73.3%, respectively. At last visit, seizure freedom rates in patients with focal-onset and generalised-onset seizures were 64.1% and 69.4%, respectively; corresponding responder rates were 84.4% and 93.9%, respec- tively. AEs were reported for 45.2% of patients, with the most frequent (≥10% of patients) being dizziness/vertigo (16.8%) and irritability (11.2%); 13.7% of patients discontinued due to AEs over 12 months. Psychiatric AEs were reported for 20.8% of patients. In conclusion, PER was effective and generally well-tolerated as monotherapy for focal-onset and/or generalised-onset seizures in everyday clinical practice. At last visit, approximately two-thirds of patients were seizure free.Supported by Eisai
071 Perampanel as early add-on therapy for focal-onset and generalised-onset seizures in clinical practice
Authors: Santamarina Estevo , Abril-Jaramillo Javier , Rodriguez-Osorio Xiana , Yamamoto Takamichi , McMurray Rob , Trinka Eugen , D’Souza Wendyl , Renna Rosaria , Villanueva Vicente 
Published: August 2022

Data from 44 pooled clinical practice studies were compared for epilepsy patients with focal-onset and/or generalised-onset seizures treated with perampanel (PER) as early (n=632) versus late add-on therapy (n=1900). Retention was assessed after 3, 6 and 12 months of PER treatment. Effectiveness assess- ments comprised responder rate (≥50% seizure frequency reduction), seizure freedom rate and rate of unchanged or worsening seizure frequency. Adverse events (AEs) and discontinuation due to AEs were evaluated. Retention was significantly higher with early versus late add-on therapy at all timepoints. At last visit, seizure freedom rate was significantly higher with early versus late add-on therapy (40.1% vs. 8.7%; p<0.001), as was responder rate (73.0% vs. 36.4%; p<0.001); and the proportion of patients with unchanged seizure frequency was significantly lower in the early versus late add-on group (10.2% vs. 31.8%; p<0.001), as was worsening seizure frequency (6.1% vs. 13.6%; p<0.001). Patients treated with early versus late add-on therapy had a significantly lower incidence of AEs (41.8% vs. 54.5%; p<0.001), psychi- atric AEs (18.3% vs. 22.2%; p=0.046), and discontinuation rates due to AEs at 12 months (15.0% vs.18.7%; p=0.045). In conclusion, PER was significantly more effective and better-tolerated as early add-on therapy in everyday clinical practice.Supported by Eisai.
What, when and how should the information about neurodegenerative disease risk in iRBD be communicated?
Authors: Chohan Harneek , Simonet Cristina , Gill Aneet , Schrag Anette , Noyce Alastair J , Pérez-Carbonell Laura 
Published: August 2022

BackgroundIdiopathic/isolated REM sleep behaviour disorder (iRBD) is characterised by vivid dreams with ‘acting-out’ behaviours due to REM sleep loss of atonia. It is associated with a risk of Parkinson’s disease (PD) and other synucleinopathies. There is uncertainty about what should be disclosed to iRBD patients in terms of future risk1.MethodsA survey was administered to patients with iRBD and participating in the PREDICT-PD study. They were invited to complete a 9-question survey exploring the information they would like to receive about the potential future implications of having iRBD.ResultsWe interviewed 31 patients (28 males, 70yo, SD 8.7y) with iRBD (mean 8.7-year disease duration, SD 6.4). A third had not received any information about the link of iRBD with other conditions by health- care professionals. More than half (61%) had searched for that information online. Most patients (87%) wanted to receive prognostic information to help them make informed decisions about their future. The preferred time for this was when a diagnosis of iRBD was made rather than when parkinsonism starts (61% vs 7%). Most wanted this information to come from their iRBD specialist (93%).ConclusionsPatients with iRBD mostly wished to receive information regarding the potential future impli- cations of having iRBD when the diagnosis of iRBD is made. Taking account of patients’ preferences is relevant to decide what, when and how to disclose prognostic information to patients with iRBD.
078 Bruns syndrome – broadening the phenotype
Authors: Seddigh Arshia , Mollan Susan , Samarasekera Shanika , Kay Andrew 
Published: August 2022

We present a 50-year-old lady with 6-months’ history of episodes of feeling weak with legs giving way triggered by sudden change of position or head-turning and no loss of consciousness. She had left tinnitus for years and one year worsening migraines with fortification spectra, visual blurring, and vertigo. ENT made a diagnosis of vestibular migraines.Her neurological examination was normal and attempted provocation of attacks with sudden changes in position and Dix-Hallpike was unsuccessful. Brain MRI revealed a large lesion obstructing foramina of Luschka-Magendie giving rise to obstructive hydrocephalus.Neuro-ophthalmology review showed bilateral papilledema and no evidence of Parinaud’s syndrome (no convergence retraction nystagmus or tectal pupils). Tumour biomarkers (bHCG-AFP-AlkPh-LDH) and body CT scan were normal. She underwent urgent CSF diversion. MDTs confirmed radiological diagnosis of epidermoid cyst awaiting debulking.Episodic headaches/vertigo with head-turning are described in Bruns syndrome manifesting as abrupt headaches, vertigo, vomiting provoked by changes in head position due to intermittent obstructive hydrocephalous (mass lesion and ball-valve mechanism). We propose patient’s acute episodes of lower limb weakness were similar phenomenon highlighting importance of imaging in stereotypical attacks after triggers.
081 Impact of co-morbid PCOS on IIH outcomes
Authors: Thaller Mark , Homer Victoria , Wakerley Benjamin , Mollan Susan , Sinclair Alexandra 
Published: August 2022

IntroductionIdiopathic intracranial hypertension (IIH) and Polycystic ovary syndrome (PCOS) affect women of reproductive age with obesity but have different hyperandrogenic profiles. The prevalence of comorbid PCOS in IIH patients is highly variable in the literature; and the longitudinal impact on visual and headache outcomes are unknown.Aims and MethodsAssess the prevalence in a prospective IIH cohort (IIH Life database (2013-2021)) based on Rotterdam criteria from questionnaire and routine clinical practice data. Secondary aim to evaluate the impact of PCOS on IIH outcomes (visual and headache).Results382 females with IIH were followed up for a median 10 (0-87) months and had presence or absence of PCOS documented. Prevalence of PCOS in IIH was 20.4% (78/382) by the Rotterdam criteria, with additional 15.2% (58) describing hyperandrogenism alone.Females with IIH and comorbid PCOS did not have significantly different visual or headache outcomes (including mean deviation and optical coherence tomography papilloedema measures).ConclusionsSymptomatic hyperandrogenism is common in IIH patients who have previously been noted to have elevated levels of testosterone. Diagnosing co-morbid PCOS is important as it can impact fertility and long-term cardiovascular risk. From an IIH management aspect, comorbid PCOS does not confer worse visual or headache outcomes.