bluuebunny/crossref_metadata_2025_split huggingface dataset:
Derivation and characterization of environmental hazard concentrations for chemical prioritization: a case study in the Great Lakes tributaries
Authors: Maloney Erin M , Corsi Steven R , Pronschinske Matthew A , DeCicco Laura A , Nott Michelle A , Frisch John R , Fuller Neil , Baldwin Austin K , Kimbrough Kimani , Edwards Michael , Hummel Stephanie L , Vinas Natalia , Villeneuve Daniel L 
Published: January 2025

Abstract
Ongoing anthropogenic activities and analytical advancements yield continuously expanding lists of environmental contaminants. This represents a challenge to environmental managers, who must prioritize chemicals for management actions (e.g., restriction, regulation, remediation) but are often hindered by resource limitations. To help facilitate prioritization efforts, this study presents several strategies for deriving environmental hazard concentrations using publicly accessible data and open-source computational tools. Using a Great Lakes tributaries aquatic monitoring dataset as a case study, environmental hazard concentrations were obtained or derived for 334 organic chemicals. These concentrations were based on (1) current water quality guidelines; (2) apical screening values; (3) apical and (4) nonapical effect concentrations from the ECOTOXicology Knowledgebase; (5) in vitro effect concentrations from the ToxCast database; (6) cytotoxic burst concentrations collated from the Comptox Dashboard; (7) “estimated screening values” derived from modeled or estimated data and available from various regulatory and nonregulatory agencies; (8) pharmaceutical potency estimates from the MaPPFAST database; and (9) quantitative structure-activity relationship (QSAR)–derived acute toxicity estimates. Environmental fate data included aquatic half-lives and bioconcentration factors collated from the Comptox Dashboard or estimated using QSARs. To identify patterns that could be used for characterization, availability of ecotoxicological concentrations and environmental fate data were evaluated. Furthermore, exceedances of hazard concentrations were evaluated and compared across diverse ecotoxicological data types. Altogether, by providing detailed methodology and practical examples generated with real monitoring data, this study demonstrated that these hazard concentration derivation strategies can be efficiently and effectively used with large, complex datasets and identified critical considerations for future prioritization efforts.
Evaluation of the sensitivity of a federally endangered freshwater mussel (Venustaconcha trabalis) to selected chemicals
Authors: Wang Ning , Ivey Christopher D , Cleveland Danielle , Kunz James L , Schapansky Rebecca , Lane Timothy , Barnhart M Chris 
Published: January 2025

Abstract
Protection of critically endangered species requires identification of factors limiting their survival and growth. Previous studies have demonstrated that unionid mussels are sensitive to some chemicals and the sensitivity was similar among different taxonomic families and tribes of mussels. However, common species of mussels were generally used in these previous studies; little is known about the sensitivity of endangered and threatened mussels relative to common species. The objective of this study was to evaluate the sensitivity of a critically endangered mussel (Tennessee bean, Venustaconcha trabalis) to seven chemicals with different modes of toxic action (ammonia, chloride, nitrite, potassium, cobalt, manganese, nickel) in acute 96-h exposures and to three chemicals (nitrite, cobalt, iron) in chronic 28-d exposures conducted following standard methods. A commonly tested mussel (fatmucket, Lampsilis siliquoidea) was also tested side-by-side with Tennessee bean in chronic exposures. Test chemicals were selected based on (1) chemicals of potential concern found in a review of existing data for the river where a population of Tennessee bean occurs or was historically present, (2) chemicals to which other mussels are sensitive, or (3) chemicals that had not been previously tested with mussels. Acute 50% effect concentrations (EC50s) for the seven chemicals from the Tennessee bean tests were within or close to the range of EC50s for other mussel species tested in previous studies, and chronic 20% effect concentrations for the three chemicals were similar between Tennessee bean and fatmucket, indicating the endangered species has sensitivity similar to other tested mussel species. Inclusion of the new mussel data in existing toxicity databases for freshwater organisms would rank one or more mussel species among the four most sensitive species to ammonia, chloride, potassium, and nickel in acute exposures and to nitrite, cobalt, and iron in chronic exposures.
Gender and cultural violence: feminist perspectives on Islamic State's heritage destruction
Authors: Childs Eleanor , Isakhan Benjamin 
Published: January 2025

Abstract
The mass destruction of heritage sites by Islamic State (IS) led to significant advances in the legal and normative frameworks governing global responses to heritage destruction in conflict. However, despite the scale and intensity of these efforts, the overwhelming majority of mandates and resolutions on heritage destruction are gender-blind. By applying a feminist International Relations perspective, we seek to answer the following research questions: how, and to what extent, do gender and heritage destruction intersect in conflict, and what explains the omission of gender in multilateral responses to heritage destruction? To answer these questions, we analyse the responses of key global agencies to the destruction carried out by IS and juxtapose them against results from in-depth semi-structured interviews conducted with a diverse group of Syrian and Iraqi women, all of whom were directly affected by attacks on their heritage. In doing so, we demonstrate the complex ways that women experience heritage destruction in conflict, thereby highlighting the systemic failures of the international community to grasp the gendered implications of such destruction. We also demonstrate how the absence of gender in institutionalized responses to heritage destruction is indicative of the relegation of feminized identities and experiences in contemporary accounts of war.
Analysing feminist foreign policy: towards the next agenda
Authors: Aran Amnon , Brummer Klaus , Smith Karen E 
Published: January 2025

Abstract
Over the past two decades an exciting and enriching theoretical and empirical debate has emerged on feminist foreign policy (FFP). However, we contend that the first wave of the debate falls short in terms of explaining the causal mechanisms that might explain why FFP rises, endures and in some cases is abandoned. In an attempt to redress this and move the debate forwards in terms of agenda, we propose bringing FFP into conversation with foreign policy analysis in relation to three key issues. Firstly, we argue that FFP scholarship should adopt an explicit conception of the state, which we contend it currently does not do. Secondly, there is value added in opening up the ‘black box’ of the state and systematically exploring the effects that both domestic political and leader-focused factors could exert on the pursuit or rejection of FFPs. Thirdly, scholarship could shift in its emphasis from the articulation to the implementation of FFPs. The next agenda of scholarship on FFP could thus contribute to a greater understanding of the drivers of decision-making, conflict and cooperation in international relations, in an era in which gender has become a flashpoint for contestation between international actors.
Effect of construction defects on construction and demolition waste management in building construction: a systematic literature review
Authors: Karunasena Gayani , Gurmu Argaw , Shooshtarian Salman , Udawatta Nilupa , Ranthika Perera C Savindi , Maqsood Tayyab 
Published: January 2025

Abstract
The occurrence of defects in building construction projects is a significant issue, leading to increased construction waste and negatively affecting sustainability and overall project performance. Despite its critical nature, the specific relationship between construction defects and waste generation has been underexplored in the literature. This study seeks to address this gap by conducting a systematic literature review of relevant publications. The research followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, conducting an extensive search across databases like Scopus and Web of Science, which resulted in the identification and content analysis of 59 pertinent articles. The findings reveal that poor workmanship, inadequate planning and scheduling, and frequent design changes are the primary causes of defect-related waste. Additionally, the study identified 12 themes, noting that the quantification of the cost of quality and the association between defect, rework and waste have not been thoroughly analyzed. The study's implications are twofold: Theoretically, it contributes to the academic understanding of the link between construction defects and waste generation, laying a foundation for future research in this area. Practically, it underscores the need for improved industry practices, such as enhanced training for construction workers, more rigorous project planning, and stricter adherence to design and specifications, to mitigate defect-related waste and promote sustainable construction practices.
Evaluation process for matching population models to regulatory decisions regarding threatened or endangered species by considering model risk
Authors: Spromberg Julann A , Hecht Scott A , Laetz Cathy A , Hawkes Tony , Baldwin David H 
Published: January 2025

Abstract
Population models can be an important tool in regulatory decision-making processes regarding natural resources, such as fisheries and rare species. Regulators presented with population models for their use often do not have the specific expertise to gauge the appropriateness of the model to their specific regulatory situation and decline their use in an abundance of caution. In other cases, regulators want to be involved with model development but may lack confidence in the utility of the models and their contribution to model development. The proposed process aims to address these concerns about using population models. The utility of population models depends on the available species data and the alignment of the model structure with regulatory needs. Importantly, the confidence in the available data and the model rigor need to match the types of decisions to be made, the time frame for reassessment, and the level of risk the regulator/agency deems appropriate. Model risk, defined as the possibility that the model is wrong or the output is misapplied, may stem from data limitations, parameter estimation uncertainty, model misspecification, or inappropriate use of a model. Here, we recommend a decision framework for considering the use of population models as a line of evidence in various regulatory contexts. The framework will assist regulators as they either work with modelers to construct new models or as they select from existing models to inform their decisions. Acknowledging and managing model risk increases the confidence of using models in regulatory contexts. As we move forward with utilizing models in regulatory decision-making, use of this process will ensure models fit the regulatory question, reduce model risk, and increase user confidence in applying models.
Life cycle assessment of copper concentrate production and improvement potentials for tailing management
Authors: Keykha Mahla , Einollahipeer Fatemeh , Abyar Hajar , Erfani Malihe 
Published: January 2025

Abstract
Due to the widespread application and development of copper, there is growing concern about increasing pressure on available resources and significant environmental repercussions. To support improvements in copper mining, this study addressed the life cycle assessment of copper concentrate production from cradle to gate, along with the feasibility of tailings reuse, which has received less attention. To fill a critical gap, the alternative use of tailings in building and landfilling disposal was also conducted. Sodium hydroxide (36.63%-95.22%), copper concentrate (4.73%-99.4%), and carboxymethyl cellulose (0.06%-46.35%) were identified as the main contributors. Marine ecotoxicity was prioritized in terms of environmental burdens (31.28%) followed by human toxicity and freshwater ecotoxicity potential. It is interesting to note that photovoltaic systems and treated wastewater provided the required energy and water for copper concentrate production, which alleviated the final impacts. For tailings management, it was initially found that landfilling intensified the environmental impacts by 1.67–65.15 times higher than copper production processing. However, the utilization of tailings in cement production and road construction provided environmental benefits and conserved resources. Summing up, this study provided additional insights into environmental indicators of the copper industry and tailings efficiency for future applications.
Operationalization of the safe and sustainable by design framework for chemicals and materials: challenges and proposed actions
Authors: Abbate Elisabetta , Ragas Ad M J , Caldeira Carla , Posthuma Leo , Garmendia Aguirre Irantzu , Devic Anne Chloe , Soeteman-Hernández Lya G , Huijbregts Mark A J , Sala Serenella 
Published: January 2025

Abstract
The production and use of chemicals and materials have both advantages and drawbacks for human and ecosystem health. This has led to a demand for carefully guided, safe, and sustainable innovation in the production of chemicals and materials, taking into consideration their entire life cycle. The European Commission's Joint Research Centre (JRC) has released the Safe and Sustainable by Design (SSbD) framework, which aims to support this objective. The SSbD framework consists of two components that are intended to be iteratively implemented throughout the innovation process: (1) the application of design principles phase, and (2) the safety and sustainability assessment phase. However, the operationalization of the framework is currently challenging. This article maps the challenges and proposes ways to address them effectively. The mapping, which is based on a literature review and stakeholder opinions, resulted in 35 challenges. The highest priority challenge is “integration of SSbD framework into the innovation process.” To begin addressing this issue, this article recommends conducting a scoping analysis to define the SSbD study. This can be achieved through implementing a tiered approach that aligns with the objectives of the innovation and the growing expertise that comes with it. The second priority challenge is “data availability, quality and uncertainty.” This can be supported by using Findability, Accessibility, Interoperability, and Reuse (FAIR) principles and by optimizing in silico methods at early stages of the innovation process. An infrastructure for data and communication is necessary to effectively engage with the entire value chain. The third priority challenge is “integration of safety and sustainability aspects,” which requires a clear definition of how to integrate those aspects in the SSbD context, and harmonization, as far as possible, of input data, assumptions, and scenario construction. This review is the first step in accelerating the operationalization of the novel SSbD concept and framework into industrial practice.
Why do labor regimes change? Worker power, the supplier squeeze, and structural transformation in the global apparel industry
Authors: Marslev Kristoffer , Whitfield Lindsay 
Published: January 2025

Abstract
Debates on labor regimes situate worker outcomes at the intersection of globalized production and specific social formations, but they do not specify how and why labor regimes change over time. This article presents a new approach to explaining how labor regimes change in the global apparel industry, the labor-led profit squeeze approach, combining insights from global production networks (GPN), development economics and labor studies. This approach argues that workers’ bargaining power is largely conditional upon processes of structural transformation. The article demonstrates this conceptual approach through a comparative analysis of the apparel export industries in Madagascar, Cambodia, and Vietnam.
A three-parameter high-resolution 3D fast Radon Transform
Authors: Ma Jitao , Zhao Kaige , Liao Zhen 
Published: January 2025

Abstract
When the underground medium exhibits anisotropy, the time slices of seismic data after normal moveout correction exhibit non-standard elliptical shapes. This complexity hinders the accurate representation by the traditional two-parameter 3D Radon transforms. To address this limitation, we introduced an additional parameter to describe ellipse rotation and integrated the frequency and curvature together, resulting in a frequency-independent transform operator, which can enhance both accuracy and computational efficiency of the algorithm. However, the algorithm suffers from low resolution in the transform domain, which limits its effectiveness in suppressing multiples with small moveouts. Existing high-resolution fast Radon transform algorithms typically adopt an iterative approach to obtain respective regularization terms for each frequency, which improves resolution but at the cost of sacrificing the frequency-independent advantage of the fast algorithm. This significantly increases computational costs. In response, we propose a novel three-parameter high-resolution 3D fast Radon transform algorithm based on the constraints derived from dominant frequency calculation. This algorithm utilizes calculation results from dominant frequency seismic data as the regularization term for all frequency calculations. By pre-computing high-resolution transform operator and its inversion, and calling them in all frequency calculations, the algorithm can effectively enhance the suppression of multiples with small moveouts while avoiding a significant increase in computational costs. To further enhance computational efficiency, we also implement a GPU-based strategy for the algorithm, which significantly improves the practicality of the approach. Both synthetic and real data tests have verified the feasibility and effectiveness of this new method.
Exploring the mechanism of pachymic acid intervention in myocardial ischemia based on network pharmacology and experimental validation
Authors: Yin Nengpin , Zhao Xuan , Yang Jin , Liu Zongjun 
Published: January 2025

Abstract

Objectives
To deeply explore the mechanism of pachymic acid (PA) intervention in myocardial ischemia, providing new ideas and methods for the treatment of myocardial ischemia.

Methods
Predict the targets of PA for improving myocardial ischemia, and conduct functional enrichment analysis using databases, such as Gene Ontology, Kyoto Encyclopedia of Genes and Genomes, and Reactome. To verify these findings, PPI network topology analysis and molecular docking were used to screen key targets and main mechanisms of action and further validated through in vitro experiments on the H9C2 cell line.

Key findings
PA can significantly alleviate myocardial damage caused by hypoxia/reoxygenation, effectively reversing the abnormalities of oxidative stress indicators such as LDH, MDA, SOD, and ROS. PA may exert its effects through 39 targets, particularly by regulating the downregulation of autophagy-related proteins LC3-II and Beclin-1 expression via MTOR, thereby inhibiting excessive autophagy in cardiomyocytes.

Conclusions
PA protects myocardial cells during myocardial ischemia through various pathways, particularly by regulating mTOR to inhibit excessive autophagy.
Modernist Synagogues for Modern Jews: Architecture and Jewish Identity in Weimar-Era Germany
Authors: Geller Jay Howard 
Published: January 2025

ABSTRACT
As Jewish communities in Germany constructed new synagogues in the 1920s and early 1930s, both the architectural style of the buildings and their use signaled a change in German–Jewish identity compared to German Jewry before the First World War. Architects wanted an aesthetic unencumbered by overtly un-Jewish associations and rejected historicism, especially “Oriental” neo-Moorish style and Christian-inspired neo-Romanesque architecture, which had characterized previous German synagogues. They opted for the aesthetic of the modernist Neues Bauen (New Building) movement, which was contemporary and regarded as not religiously didactic. In addition, the new buildings were purposely designed and built to serve as centers for Jewish cultural and social life rather than solely or almost solely as houses of worship, in contrast to nineteenth-century synagogues.
Hierarchical Bayesian inference on an analytical toy model of the LISA MBHB population
Authors: Langen Vivienne , Tamanini Nicola , Marsat Sylvain , Bortolas Elisa 
Published: January 2025

ABSTRACT
Massive black hole binary (MBHB) mergers detected by the Laser Interferometer Space Antenna (LISA) will provide insights on their formation via dark matter (DM) halo and galaxy mergers. We present a novel Bayesian inference pipeline to infer the properties of an analytical model describing the MBHB population. The flexibility of our approach allows for exploring the uncertain range of MBH seeding and growth, as well as the interplay between MBH and galactic astrophysics. This flexibility is fundamental for the successful implementation and optimization of hierarchical Bayesian parameter estimation that we apply to the LISA MBHB population for the first time. Our inferred population hyper-parameters are chosen as proxies to characterize the MBH–DM halo mass scaling relation, the occupation fraction of MBHs in DM haloes and the delay between halo and MBHB mergers. We find that LISA will provide tight constraints at the lower-end of the mass scaling relation, complementing EM observations which are biased towards large masses. Furthermore, our results suggest that LISA will constrain features of the MBH occupation fraction at high redshift, as well as time delays around a few hundreds of Myr. Although our analysis clearly shows that results are affected by a degeneracy between the efficiency of time delays and the overall abundance of MBH that can potentially merge, they open the possibility to constrain dynamical evolution times such as the dynamical friction. Our analysis is a first attempt at developing hierarchical Bayesian inference to the LISA MBHB population, opening the way for further investigations.