bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structural organization of periodontium and morphological changes in its components in modeled periodontitis and its correction in rats
Authors: Biguliak H. , Klishch I. 
Published: January 2022

Introduction. The aim of our research was to study peculiar features of morphological changes in the components of the periodontium in the modeled acute periodontitis and its correction by stem cells.
Materials and Methods. The results of histological study of periodontal tissues of the animals with acute experimental periodontitis, which was corrected using human mesenchymal stem cells as well as rat muscle stem cells, were analysed. Depending on the treatment, the animals were divided into 4 groups: the 1st group – the animals without pathology (intact); the 2nd – the animals with modeled acute periodontitis; the 3rd – the animals with periodontitis corrected by human mesenchymal stem cells, the 4th – the animals with periodontitis corrected using rat muscle stem cells.
Results and Discussion. According to the results of the research it was established that correction by human mesenchymal stem cells and rats muscular stem cells had positive effect on a course of the modeled pathological process. The morphological changes characteristic of periodontitis gradually reduced, i.e. the normal blood supply to the tissues restored, the arteries were less full-blooded, the tone of their walls decreased. Consequently, the swelling of the tissues gradually decreased becoming of original size. The polymorphonuclear infiltration fields decreased and gradually disappeared. Osteoblasts promoted restoration of the bone structure of the jaw alveolar process. The size of the periodontal pocket decreased, and in some areas it fully closed as a result of complete adhesion of the mucous membrane of the gums to the tooth, which rose on its surface upwards.
Conclusions. In the experimental modeling of acute periodontitis the destructive changes in the epithelium and connective tissue stroma, impaired blood flow, inflammatory response in the gum tissue were present. The correction by means of human mesenchymal stem cells as well as rat muscle stem cells had positive effect on the modeled pathological process: the morphological changes characteristic of periodontitis gradually reduced, normal blood supply to tissues restored, polymorphonuclear infiltration fields gradually decreased and disappeared. The bone structure of the jaw alveolar process restored owing to osteoblasts. The size of the periodontal pocket decreased; in some cases, they closed completely as a result of complete adhesion of the mucous membrane of the gums to the tooth, which rose on its surface upwards.
Risk factors for venous thrombosis in patients with endoprosthetics of hip joints
Authors: Venher Ihor , Kostiv Sviatoslav , Khvalyboha Dymytrii 
Published: January 2022

Background. Important part of orthopaedic surgery is endoprosthetics of hip joints, which eliminates pain syndrome, restores the amplitude of movements and the support ability of the lower limb. But there is a number of complications; venous thromboembolism among them occupies a leading place.
Material and methods. 219 patients with a mean age of 64.7 ± 3.8 years were operated. In 137 (62.1%) observations, total cement hip replacement was performed for osteoarthritis. 82 (37.4%) patients received total and unipolar cement hip replacement for cervical femoral neck fractures.
Results. Clinical manifestations of non-specific connective tissue dysplasia were detected in 83 (37.9%) patients, which were confirmed by the laboratory determination of the level of general, bound and free oxyproline. In the postoperative period, the thrombotic process in the venous system of the inferior vena cava was diagnosed in 23 (10.5%) observations. Operative intervention on the hip joint in patients with nonspecific dysplasia of connective tissue in 11 (13.3%) cases was complicated by the development of venous thrombosis. In patients without non-specific connective tissue dysplasia, postoperative thrombosis in the system of the inferior vena cava was diagnosed in 12 (8.8%) observations.
Conclusions. Patients with osteoarthrosis of the hip joint and the femoral neck fracture accompanied by the non-specific dysplasia of the connective tissue are characterized by expressed levels of endothelial dysfunction and increased activity of the blood-coagulation system.
Hospital management strategy in the aspect of visualization of the pandemic COVID-19
Authors: Kanownik Greta 
Published: January 2022

The article addresses an important issue regarding the impact of the coronavirus pandemic on the operation of hospitals and the use of management strategies at the present time and in reality after the pandemic. Based on the analysis performed, the article indicates four key areas that require immediate action to improve the functioning of the health care system and maintain the public health of the population. Based on the analysis of 9 crisis levers of the business model of A. Osterwalder, Y. Pigneur, four main areas requiring immediate intervention were identified, namely: development of medical personnel, development of computerization and digital competences, optimization of revenues and costs, identification of decision-making centers - appropriate division of tasks and responsibility.
In these areas, the Polish health care system has failed, they require urgent strengthening and strategic long-term solutions, which will translate into optimization of activities aimed at securing the health of the society.
It turns out that during the pandemic, it was not costs that turned out to be the biggest problem, but above all staff shortages, lack of access to health services, or equipment and organizational shortages. The time of the pandemic has shown that the researchers' theories that quality and not cost are the most important have proved successful. According to M.E. Porter and E. Teisberg, despite the limitations, the health care system can achieve excellent results in terms of both quality and effectiveness, which, however, often requires transformation and implementation of new competition rules aimed at increasing the value created.
Liver dysfunction in children with community-acquired pneumonia: the role of infectious and inflammatory markers
Authors: Dudnyk Veronika , Pasik Valentyna 
Published: January 2022

Markers of infectious-inflammatory process were studied by determining the levels of pro-inflammatory cytokines - interleukin (IL) 1 and IL-6 and proteins of the acute phase of inflammation - C-reactive protein (CRP) and fibrinogen in the serum of children with community-acquired pneumonia.
It was found that the course of community-acquired pneumonia is accompanied by an increase in serum concentrations of IL-1 and IL-6 in children in parallel with the disease severity. The synthesis of pro-inflammatory cytokines stimulates the production of acute CRP, but reduces the concentration of fibrinogen in the serum of sick children. The revealed connections between the content of the studied cytokines at the systemic level and multidirectional changes in the indicators of the acute phase of inflammation indicate a violation of the liver, where proteins are synthesized in the study.
It is shown that with increasing severity of pneumonia, the enzyme activity of aminotransferases - alanine aminotransferase (ALT) and aspartate aminotransferase (AST) in the serum of children increases with a simultaneous decrease in the de Ritis coefficient, indicating "hepatic" genesis. High levels of aminotransferase is closely correlated with the activity of the infectious-inflammatory process, as indicated by the positive correlation between the level of IL-1 and ALT (r = 0.047) and AST (r = 0.111). At the same time, there is a negative correlation between the levels of IL-1, CRP and the activity of aminotransferases in blood serum.
Influence of some anthropometric, motor and bone mass parameters on short distance running
Authors: Ramadani L. , Rashiti N. , Bekolli L. , Heta G. 
Published: January 2022

The knowledge on morphological development and their impact on motor skills in short distance athletes should be one of the main preoccupations of athletics coaches, because any scientific research in the field of physical culture and sports is concerned with proving the development and evaluation of anthropological characteristics which are responsible in achieving success in athletics.The purpose of this paper is to prove the impact of some anthropometric, motor-specific characteristics and those of bone weight in short distance running, specifically in 100 meters, with students aged 19 ± 6 years, of the Faculty of Physical Education and Sports in Pristina.The sample of this research included a total of 75 students aged 19 of the Faculty of Physical Education and Sports in Pristina.The variables which were applied in this research were 7 anthropometric variables and 6 motor variables and 1 specific motor variable.Regression analysis in the manifest space was applied to determine the relationship between predictive variables (anthropometric and motor characteristics) and criterion variable (100 m running).
Problem baby blues wśród polskich położnic – zakres posiadanej wiedzy wśród studentów medycyny
Authors: Nawrocki Maciej , Zwierzyńska Anna , Wojciechowski Piotr , Nowakowska Ilona , Wasiak Wojciech , Gruszka Jakub , Adamczyk-Gruszka Olga 
Published: January 2022

Wstęp
Zaburzenia psychiczne stanowią częsty problem kobiet w okresie połogu. Baby blues jest bezpośrednim stanem alarmowym i zagrożeniem dla matki. Może rozwinąć się w rzeczywistą depresję czy psychozę poporodową. Za patogenezę tego zjawiska uznawane są zmiany hormonalne związane ze spadkiem poziomu estradiolu, progesteronu i prolaktyny po porodzie. Przygnębienie poporodowe jest zaburzeniem samoograniczającym się i przejściowym. Nie powinno być jednak lekceważone. Najważniejsze jest wczesne rozpoznanie objawów i interwencja.
Cel pracy
Celem pracy była ocena wiedzy studentów na temat zjawiska baby blues oraz wpływu czynników takich jak miejsce zamieszkania czy poziom wykształcenia na stan wiedzy.
Materiał i metody
Badaniem zostało objętych 318 studentów medycyny UJK. Dane zostały zebrane za pomocą kwestionariusza autorskiego. Komisja Bioetyczna zatwierdziła badanie. Analiza statystyczna przeprowadzona została za pomocą programu komputerowego Statistica 13.
Wyniki i wnioski

Największy odsetek respondentów mieści się w grupie wiekowej 20-30 lat. Najbardziej liczną grupę stanowią mieszkańcy miast.
Średni poziom wiedzy respondentów na temat baby blues wynosi 75%.
Najczęściej wskazywanym źródłem wiedzy są Internet oraz programy telewizyjne. Ważne jest uświadomienie pacjentom w jaki sposób dobierać rzetelne źródło informacji.
Edukacja prozdrowotna ma kluczowe znaczenie dla przyszłych rodziców. Może przekładać się na zmniejszenie poziomu stresu związanego z nową sytuacją jaka jest posiadanie potomstwa.
Efficacy and safety of ashwagandha root extract in the treatment of insomnia, anxiety and reducing stress – literature review
Authors: Mazur Karol , Lewicki Marcin , Mazur Dominika , Smoleń Agata 
Published: January 2022

Insomnia, anxiety and stress are common complaints of people living today. Together, these factors can significantly reduce the quality of people's lives and disrupt relationships. Insomnia is a health problem connected with the difficulty falling asleep, waking early, waking during sleep, or poor quality of sleep, the consequences of which during the day are a feeling of being fatigue, reduced well-being, irritability, impaired concentration and learning ability. Anxiety is an emotional state related with anticipation of danger coming from the outside or coming from inside the organism, manifesting itself as feeling of uneasiness, tension, embarrassment, threat. Stress is a disturbance of body homeostasis caused by a physical or psychological factor.
The aim of this study was to assess the efficacy and safety of ashwagandha root extract in the treatment of insomnia, anxiety and reducing stress. Our study material consisted of publications, which were found in PubMed, ResearchGate and Google Scholar databases. In order to find the proper publications, the search has been conducted with the use of a combination of key words like: ''ashawagandha'', ''insomnia'', ''anxiety'', ''stress". The first step was to find proper publications from the last 5 years. The second step was to carry out an overview of the found publications.
Currently a lot of researches is being conducted to find natural substances that are just as effective as pharmacotherapy in the treatment of insomnia, anxiety and reducing stress, but without the side effects. Some researchers have focused their attention to the ashwagandha root extract. Results of mentioned studies proved the efficacy and safety of ashwagandha root extract. However, further research is needed to estabilish the role of ashwagandha root extract in the treatment of insomnia, anxiety and reducing stress.
Age features of O2 mass transfer regimes in adolescents’ body at rest
Authors: Komolafe D. , Filippov M. , Ilyin V. , Klimenko A. 
Published: January 2022

The results of complex studies of the quantitative relationship between the stage-by-stage mass transfer of O2 and the efficiency of cardiorespiratory system functioning in relation to its consumption in adolescents’ body under conditions of relative rest are presented.
The results obtained show that in adolescents, the modes of mass transfer of O2 in the body and the nature of the respiratory and circulatory systems functioning in relation to its consumption have a number of age-related differences compared with adult men. So, in adolescents, the external respiration system at rest functions less economically than in adults. Each liter of O2 consumed by adolescents is extracted from almost 3 liters more than in adults the amount of air ventilated per minute through the lungs. The volumetric indicators of blood circulation are also higher in adolescents, which may indicate the influence of neuro-humoral rearrangements in the body during the pubertal period. The coefficient of oxygen utilization by tissues from arterial blood in adolescents turned out to be significantly higher, which may characterize a higher tension of tissue metabolic processes.
Wybrane aspekty medyczne i społeczne pandemii Covid-19
Authors: Cipora Elżbieta , Mielnik Aneta 
Published: January 2022

Pandemia Covid-19 stanowi ogromne zagrożenie dla zdrowia i życia ludzkiego oraz funkcjonowania społeczno-gospodarczego. Celem pracy jest przedstawienie wybranych aspektów medycznych i społecznych związanych z pandemią Covid-19. Jako metodę badań zastosowano przegląd i analizę piśmiennictwa pochodzącego z bazy PubMed uzupełnione o raporty epidemiologiczne. Do wyszukania publikacji użyto następujących słów kluczowych: „Covid-19”, „medical aspects of Covid-19”, „social aspects of Covid-19”. Pandemia Covid-19 spowodowała destabilizację zdrowia publicznego na skalę światową i pozostawiła wiele negatywnych skutków społecznych. Była przyczyną globalnego kryzysu gospodarczego i ekonomicznego. Covid-19 określone zostało mianem nagłego niekorzystnego i wielowymiarowego doświadczenia medycznego i społecznego, którego następstwa występują obecnie i będą odczuwane jeszcze przez wiele lat. Należy monitorować sytuację epidemiologiczną, zdrowotną i ekonomiczną społeczeństwa i podejmować działania zmierzające do zmniejszenia nasilenia negatywnych skutków pandemii Covid-19.
Parental Perceptions of Autism Spectrum Disorder in Latinx and Black Sociocultural Contexts: A Systematic Review
Authors: Rivera-Figueroa Karla , Marfo Nana Yaa A. , Eigsti Inge-Marie 
Published: January 2022

Abstract
Parents of children with autism spectrum disorder (ASD) face challenges in accessing diagnostic and treatment services; these challenges vary by race, ethnicity, and culture. This systematic review examines parental perceptions of ASD within Latinx and Black American communities. Findings indicate that interconnections with family and religious groups promoted positive coping and describe positive impacts of having a child with ASD. Relative to White families, community members reported reduced access to information and more inaccurate beliefs about ASD, higher levels of ASD-related stigma, and more negative experiences with healthcare providers, which serve to exacerbate healthcare disparities. Conclusions are limited by an underrepresentation of minority groups in research. We call for efforts to address the specific needs of racial and ethnic minorities.
Fast on-line rubidium DPAL atomic concentration measurement by 420  nm
probe laser: erratum
Authors: Zhao Hui-Zi , Wang Hong-Yan , Tang Hao , Li Liang , Yang Zi-Ning , Yang Wei-Qiang , Han Kai , Xu Xiao-Jun 
Published: January 2022

We present an erratum to our recent work [Appl. Opt.
60, 10862 (2021)APOPAI0003-693510.1364/AO.440435] that
corrects errors in Fig. 4 and the body of the paper. The corrections
do not affect the results and conclusions of the original paper.
High-Q Fano resonance in all-dielectric metasurfaces for molecular fingerprint detection
Authors: Hadi Badri S. , Gilarlue M. M. , SaeidNahaei Sanam , Kim Jong Su 
Published: January 2022

We present and numerically investigate a high-quality factor (high-

Q

) meta-atom with Fano resonance. Numerical simulations indicate that the designed meta-atom has a single sharp Fano resonance in the 1350–1750 1/cm range. Moreover, the frequency of the single resonance can be tuned in this frequency range by scaling the meta-atom. We exploit these properties to design a pixelated metasurface for spectrometer-less molecular fingerprint retrieval. The proposed meta-atom with an average quality factor of 2000 makes it possible to decrease the scaling step of metapixels without introducing resonance overlap between the metapixels, leading to higher precision in label-free and nondestructive identification of molecular fingerprints.
Tomographic phase and attenuation extraction for a sample composed of unknown materials using x-ray propagation-based phase-contrast imaging
Authors: Alloo S. J. , Paganin D. M. , Morgan K. S. , Gureyev T. E. , Mayo S. C. , Mohammadi S. , Lockie D. , Menk R. H. , Arfelli F. , Zanconati F. , Tromba G. , Pavlov K. M. 
Published: January 2022

Propagation-based phase-contrast x-ray imaging (PB-PCXI) generates image contrast by utilizing sample-imposed phase-shifts. This has proven useful when imaging weakly attenuating samples, as conventional attenuation-based imaging does not always provide adequate contrast. We present a PB-PCXI algorithm capable of extracting the x-ray attenuation
β
and refraction
δ
, components of the complex refractive index of distinct materials within an unknown sample. The method involves curve fitting an error-function-based model to a phase-retrieved interface in a PB-PCXI tomographic reconstruction, which is obtained when Paganin-type phase retrieval is applied with incorrect values of δ and β. The fit parameters can then be used to calculate true
δ
and
β
values for composite materials. This approach requires no a priori sample information, making it broadly applicable. Our PB-PCXI reconstruction is single-distance, requiring only one exposure per tomographic angle, which is important for radiosensitive samples. We apply this approach to a breast-tissue sample, recovering the refraction component
δ
, with 0.6–2.4% accuracy compared with theoretical values.
Influence of slow light effect on trapping force in optical tweezers
Authors: Chen Haotian , Lin Huichuan , Jones P. H. , Chen Ziyang , Luo Songjie , Pu Jixiong 
Published: January 2022

We investigate the optical trapping of polystyrene microspheres in optical tweezers. The transverse capture gradient forces of polystyrene microspheres with different numerical aperture are theoretically and experimentally evaluated by the power spectral density roll-off method. It is found that the trapping force of the experimental measurement is much stronger than that of the theoretical results. The discordance is attributed to the slow light effect near the focus, which has been found in recent years [Science 347, 857 (2015)10.1126/science.aaa3035; Opt. Express 18, 10822 (2010)10.1364/OE.18.010822; Opt. Commun. 332, 164 (2014)10.1016/j.optcom.2014.06.057]. The modified trapping force of the theoretical results by considering the slow light effect near the focus is well consistent with that of the experimental results.
Detection and genome characterization of Middelburg virus strains isolated from CSF and whole blood samples of humans with neurological manifestations in South Africa
Authors: Fourie Isabel , Williams June , Ismail Arshad , Jansen van Vuren Petrus , Stoltz Anton , Venter Marietjie 
Published: January 2022

Background
The Old world Alphavirus, Middelburg virus (MIDV), is not well known and although a few cases associated with animal illness have previously been described from Southern Africa, there has been no investigation into the association of the virus with human illness. The current study aimed to investigate possible association of MIDV infection with febrile or neurological manifestations in hospitalized or symptomatic patients fromGauteng, South Africa.

Methods
This study is a descriptive retrospective and prospective laboratory based study. Archived cerebrospinal fluid (CSF) samples submitted to the National Health Laboratory Service (NHLS), Tshwane Academic division for viral investigation from public sector hospitals in Gauteng as well as EDTA (ethylenediaminetetraacetic acid) whole blood samples from ad hoc cases of veterinary students, presenting with neurological and febrile illness, were selected and screened for the presence of alphaviruses using real-time reverse transcription(rtRT) PCR.Virus isolations from rtRT-PCR positive samples were conducted in Vero cell culture and used to obtain full genome sequences. Basic descriptive statistical analysis was conducted using EpiInfo.

Results
MIDV was detected by rtRT-PCR in 3/187 retrospective CSF specimens obtained from the NHLS from hospitalised patients in the Tshwane region of Gauteng and 1/2 EDTA samples submitted in the same year (2017) from ad hoc query arbovirus cases from veterinary students from the Faculty of Veterinary Science University of Pretoria.Full genome sequences were obtained for virus isolates from two cases; one from an EDTA whole blood sample (ad hoc case) and another from a CSF sample (NHLS sample).Two of the four Middelburg virus positive cases,for which clinical information was available, had other comorbidities or infections at the time of infection.

Conclusion
Detection of MIDV in CSF of patients with neurological manifestations suggests that the virus should be investigated as a human pathogen with the potential of causing or contributing to neurological signs in children and adults.
COMPARATIVE ANALYSIS OF THE CHEMICAL COMPOSITION OF LIPOPHILIC FRACTIONS OF SHOOTS OF THREE SPECIES OF THE GENUS CRATAEGUS L.
Authors: Khasanova Svetlana Rashitovna , Kudashkina Natal'ya Vladimirovna , Gusakova Valeriya Andreyevna , Jalalova Nadira Begim Kursanovna 
Published: January 2022

The article presents research of the chemical composition of lipophilic fractions of shoots Crataegus sanguinea Pall. (Rosaceae), Crataegus submollis Sarg. (Rosaceae) and Crataegus almaatensis Pojark. (Rosaceae). Lipophilic extract is obtained from petroleum ether. The components of the lipophilic fraction were separated and identified by gas chromatography with mass spectrometry. 36 compounds were identified in lipophilic fractions: hydrocarbons, fatty acids, sugars, phenolic compounds, diterpenoids and sterols. Their presence may determine the pharmacological properties of hawthorn shoots. These research expand information about the chemical composition of these hawthorn species and can be used in the development of a new drug.