bluuebunny/crossref_metadata_2025_split huggingface dataset:
Variation in histone configurations correlates with gene expression across nine inbred strains of mice
Authors: Tyler Anna L. , Spruce Catrina , Kursawe Romy , Haber Annat , Ball Robyn L. , Pitman Wendy A. , Fine Alexander D. , Raghupathy Narayanan , Walker Michael , Philip Vivek M. , Baker Christopher L. , Mahoney J. Matthew , Churchill Gary A. , Trowbridge Jennifer J. , Stitzel Michael L. , Paigen Kenneth , Petkov Petko M. , Carter Gregory W. 
Published: November 2022

AbstractIt is well established that epigenetic features, such as histone modifications and DNA methylation, are associated with variation in gene expression across cell types. Less well known is the extent to which epigenetic states vary across genetically diverse individuals, and whether such variation corresponds to inter-individual variation in gene expression. To investigate genetically driven variation in epigenetics, we conducted a survey of epigenetic modifications and gene expression in hepatocytes of nine inbred mouse strains. We surveyed four histone modifications (H3K4me1, H3K4me3, H3K27me3, and H3K27ac), and DNA methylation. We used ChromHMM to identify 14 chromatin states, each of which represented a distinct combination of the four histone modifications. We found that chromatin states varied widely across the nine strains and that epigenetic state was strongly correlated with local gene expression. We replicated this correspondence between chromatin state and gene expression in an independent population of Diversity Outbred mice in which we imputed local chromatin state. In contrast, we found that DNA methylation did not vary across the inbred strains and was not correlated with variation in gene expression in DO mice. This work suggests that chromatin state is highly influenced by local genotype and may be a primary mode through which expression quantitative trait loci (eQTLs) are mediated. Through examples, we demonstrate that naturally occurring chromatin state variation, in conjunction with gene expression, can aid in functional annotation of the mouse genome. Finally, we provide a data resource that documents variation in chromatin state in hepatocytes across genetically distinct mice.
Promoting gender – Equitable agricultural value chains: the role of corporate social responsibility in Nigeria's Niger Delta
Authors: Uduji Joseph Ikechukwu , Okolo-Obasi Elda Nduka 
Published: November 2022

PurposeThe purpose of this paper is to critically examine the multinational oil companies' (MOC) corporate social responsibility (CSR) initiatives in Nigeria. Its special focus is to investigate the impact of the global memorandum of understanding (GMoU) on promoting gender-equitable agricultural value chains in the Niger Delta region.Design/methodology/approachThis paper adopts a quasi-experimental design that used survey research technique, aimed at gathering information from a representative sample of the population, as it is essentially cross-sectional, describing and interpreting the current situation. A total of 760 rural women (380 from the treatment group and another 380 from the control group) were sampled across the Niger Delta region.FindingsThe results from the use of a combination of a logit model and propensity score matching indicate a significant relationship between GMoU model and gender-equitable agricultural value chains in the Niger Delta, Nigeria.Research limitations/implicationsThis study implies that CSR of MOCs is a critical factor in the need to integrating gender into agricultural value chains, achieving the goal of increasing agricultural growth and expanding the stable food supply.Originality/valueThis research contributes to gender debate in agricultural value chains from a CSR perspective in developing countries and rationale for demands for social projects by host communities. It concludes that business has an obligation to help in solving problems of public concern.
How perceived attributes of livestreaming commerce influence customer engagement: a social support perspective
Authors: Qin Fang , Le Wei , Zhang Min , Deng Yujia 
Published: November 2022

PurposeThe boom in livestreaming commerce (LSC) has brought significant changes to social interaction methods. Understanding customer engagement in LSC is critical for online sellers who try to enhance the social influence and improve marketing effectiveness of LSC. Based on the stimulus–organism–response (S–O–R) paradigm, this study aims to develop a model to investigate the effects of perceived attributes of LSC (real-time interaction, perceived proximity and perceived authenticity) on social support (informational and emotional support) and subsequent engagement.Design/methodology/approachAn online survey is conducted to collect data from LSC customers, and data are analyzed using SPSS and SmartPLS.FindingsThe results indicate that informational and emotional support are positively affected by real-time interaction, perceived proximity and perceived authenticity. In turn, informational and emotional support enable and mediate the prediction of customer engagement intention in LSC.Originality/valuePrior LSC studies tend to focus on the motivation influencing LSC engagement from the perspective of perceived value. This study confirms the importance of perceived attributes of LSC in driving customer engagement from the perspective of social support.
Adoption of artificial intelligence in financial services: a policy framework
Authors: Kumari Bharti , Kaur Jaspreet , Swami Sanjeev 
Published: November 2022

PurposeA crucial contemporary policy question for financial service organizations of being resilient across the globe calls for rethinking and renovating by adopting and adapting to the technologies of artificial intelligence (AI). The purpose of this study is to propose a policy framework for adoption of AI in the finance sector by exploring the driving factors through systems approach.Design/methodology/approachBased on literature review and discussions with experts from both industry and academia, nine enablers were shortlisted, which were used in the questionnaire survey to determine ranks of enablers. Further, the study developed the interpretive structural model (ISM) with the help of experts.FindingsThe ISM digraph developed with the help of the experts, resulted in the enablers like anticipated profitability, contactless solutions, credit risk management and software vendor support as dependent factors and stood at the top of the ISM. On the other hand, factors like availability of the data, technical infrastructure and funds are the most driving factors, which lie on the bottom of the ISM.Research limitations/implicationsThe study provides implications and policy recommendations for the practicing managers and government agencies approaching the digital transformation towards the adoption of AI in the finance ecosystem.Originality/valueThe paper uses the systems approach for the development of the ISM of the enabling factors for the adoption of AI technology. On the basis of the results, the study proposes a policy framework to accelerate the functioning of the finance ecosystem with AI technology.
Sex‐specific flower resource use in hummingbird communities
Authors: Ornelas Juan Francisco 
Published: November 2022

AbstractResearch Highlight: Maglianesi, M. A., Maruyama, P. K., Temeles, E. J., Schleuning, M., Zanata, T. B., Sazima, M., Gutiérrez‐Zamora, A., Marín‐Gómez, O. H., Rosero‐Lasprilla, L., Ramírez‐Burbano, M. B., Ruffini, A. E., Salamanca‐Reyes, J. R., Sazima, I., Nuñez‐Rosas, L. E., Arizmendi, M. C., Rahbek, C., & Dalsgaard, B. (2022). Behavioural and morphological traits influence sex‐specific floral resource use by hummingbirds across the Americas. Journal of Animal Ecology, 00: 00–00. https://doi.org/10.1111/1365‐2656.13746. In their paper on intersexual differences in niche breadth and niche overlap in floral resource use in hummingbird communities, Maglianesi et al. compiled data of plant–hummingbird interactions based on pollen loads, and territoriality and morphological traits for 31 hummingbird species, and investigated whether patterns of resource use by females and males were related to sexual dimorphism and foraging behaviour. While accounting for evolutionary relatedness among species, the authors found a high level of resource partitioning between sexes (broader and more dissimilar floral niche breadth in females) and the sex‐specific resource use by hummingbird species was related to territoriality and morphological traits; niche overlap between sexes was greater for territorial than non‐territorial species, and lower for species with greater sexual dimorphism in bill curvature. This paper addresses two very timely issues, on the one hand on resource partitioning by sex to reduce intersexual competition in hummingbirds, and on the other hand highlight the much needed information on foraging ecology of female hummingbirds for better understanding of intersexual variation in shaping coexistence and species diversity in hummingbird communities and the interactions between plants and their hummingbird pollinators.
The effect of practice and expectancy of inferential questions on poor comprehenders' inferential processing and monitoring
Authors: Yeari Menahem , Avramovich Adi 
Published: November 2022

BackgroundPrevious studies have shown that undergraduates improve their answering and monitoring accuracy when they exclusively practice and expect inferential questions after reading. This study examined whether children with poor comprehension, who struggle particularly with inferential questions, would benefit from similar practice with and without feedback.MethodsTo address this question, 44 poor comprehenders and 44 control participants from 6th–9th grades practiced answering literal or inferential questions after reading each of three texts. They were also asked to predict their success in these questions, whereas some received feedback on their prediction (monitoring) accuracy. Then, participants read an additional three texts, but answered both practiced and unpracticed types of questions after reading all texts. They also predicted their success after reading each text.ResultsBoth poor and good comprehenders answered literal questions more accurately when they had practiced. However, only good comprehenders improved their answering of inferential questions when they had practiced. No differences were found between the groups in monitoring accuracy. Feedback had a positive effect on answering accuracy, irrespective of practice.ConclusionsPoor comprehenders differentiate to some extent between literal and inferential questions and are flexible enough to execute a different text processing plan for each type of questions. However, they presumably lack the knowledge and/or resources to execute inferential processing efficiently during reading. Moreover, all children seem to have difficulty with comprehension monitoring. Practicing and/or expecting one type of questions, with or without feedback, is insufficient for improving this ability.
Do climatic factors induce rural migration? Empirical evidence from cotton farmers in Benin
Authors: Mounirou Ichaou 
Published: November 2022

AbstractSustainable agriculture is essential for food security, which can sometimes be undermined by rural migration triggered by many factors, including climate change. This article aims to analyze its effects on the dynamic of rural migration. Using a database of 623 agricultural households, a multivariate probit model (MVP) was estimated. The results show that regardless of the nature of migration, variables related to climate factors positively and significantly affect decisions to move. In addition, other non‐climatic variables relevant to environmental migration are cattle transhumance, which creates conflicts between herders and farmers, along with poor access to agricultural credit, agricultural and off‐farm income. Gender, age, household size, accessibility to educational and health facilities in the area of origin and experience in agricultural production must be considered. Emphasis should be placed on agricultural policies aimed at diversifying the income sources of rural households in developing countries. The study highlights the importance of both farm and non‐farm income in controlling migration. In the case of our study area, it is the combination of livestock and agriculture that seems to respond best. Producers are encouraged to diversify crops and, during periods of climatic disruption, the priority of households should be based on the production of food crops for subsistence.
Impacts of oxygen deficiency on embryo life‐history traits of migratory locust Locusta migratoria from low and high altitudes
Authors: Huang Xianliang , Du Qianli , Wang Lijing , Chen Bing 
Published: November 2022

AbstractHypoxia challenges aerobic organisms in numerous environments, and hypoxic conditions may become more severe under future climate‐change scenarios. The impact of hypoxia on the development of terrestrial insect embryos is not well understood. Here, to address this gap, embryonic life‐history traits of migratory locust Locusta migratoria from low‐altitude and high‐altitude regions were compared under 2 oxygen levels: normoxia (i.e., 21 kPa oxygen partial pressure and mild hypoxia (i.e., 10 kPa oxygen partial pressure). Our results demonstrated that, whether reared under normoxia or mild hypoxia, L. migratoria from high‐altitude populations had longer developmental times, reduced weight, and lower mean relative growth rate as compared with those from low‐altitude populations. When transferred from normoxia to mild hypoxia, nearly all the tested life‐history traits presented significant negative changes in the low‐altitude populations, but not in the high‐altitude populations. The factor ‘strain’ alone explained 18.26%–54.59% of the total variation for traits, suggesting that the phenotypic differences between L. migratoria populations from the 2 altitudes could be driven by genetic variation. Significant genetic correlations were found between life‐history traits, and most of these showed differentiation between the 2 altitudinal gradients. G‐matrix comparisons showed significant structural differences between L. migratoria from the 2 regions, as well as several negative covariances (i.e., trade‐offs) between traits in the low‐altitude populations. Overall, our study provides clear evidence that evolutionary divergence of embryonic traits between L. migratoria populations from different altitudes has occurred.
Baseline susceptibility of Helicoverpa armigera, Plutella xylostella, and Spodoptera frugiperda to the meta‐diamide insecticide broflanilide
Authors: Wang Xingliang , Shi Tailong , Tang Ping , Liu Shengnan , Hou Bofeng , Jiang Dong , Lu Jingde , Yang Yihua , Carrière Yves , Wu Yidong 
Published: November 2022

AbstractBroflanilide is a novel meta‐diamide insecticide that acts as a γ‐aminobutyric acid‐gated chloride channel allosteric modulator. With its unique mode of action, broflanilide has no known cross‐resistance with existing insecticides and is expected to be an effective tool for the management of insecticide resistance. Establishing the baseline susceptibility to this insecticide is an essential step for developing and implementing effective resistance management strategies. Here we evaluated the baseline susceptibility to broflanilide for 3 cosmopolitan lepidopteran pest species, Helicoverpa armigera, Plutella xylostella, and Spodoptera frugiperda. Broflanilide exhibited high activity against populations sampled in the major distribution range of these pests in China, with median lethal concentrations (LC50) ranging between 0.209 and 0.684, 0.076 and 0.336, and 0.075 and 0.219 mg/L for H. armigera, P. xylostella, and S. frugiperda, respectively. Among‐population variability in susceptibility to broflanilide was moderate for H. armigera (3.3‐fold), P. xylostella (4.4‐fold), and S. frugiperda (2.9‐fold). The recommended diagnostic concentrations for H. armigera, P. xylostella, and S. frugiperda were 8, 4, and 2 mg/L, respectively. Little or no cross‐resistance to broflanilide was detected in 3 diamide‐resistant strains of P. xylostella and 1 spinosyns‐resistant strain of S. frugiperda. Our results provide critical information for the development of effective resistance management programs to sustain efficacy of broflanilide against these key lepidopteran pests.
Electroencephalogram pattern association with drug‐related cues in a long‐duration virtual reality environment in patients with methamphetamine use disorder
Authors: Ding Xinfang , Li Yuanhui , Zhang Tianjiao , Li Dai , Luo Sean X. , Liu Xiang , Hao Wei 
Published: November 2022

AbstractThe cognitive processing of drug‐related cues and the subsequent dysregulation of behaviour play a central role in the pathophysiology of substance use disorders. Prior studies are limited by small sample sizes and a lack of immersion in stimulus presentation. In the present study, we recruited patients with methamphetamine use disorder (MUD; N = 1099) from four compulsory isolated detoxification centres and healthy control participants (N = 305). With a 12‐min‐long virtual reality (VR) protocol stimulus, we discovered that patients showed a decrease in electroencephalogram (EEG) power across alpha to gamma bands in anterior scalp regions under methamphetamine‐related VR stimuli (e.g. a glass pipe and medical tubing) compared with the control stimuli (e.g. balls and cubes). Analysis of variance (ANOVA) showed that the interaction effects of stimuli type and group were significant in five EEG bands. Using generalised linear models, we classified the stimuli type (i.e. drug‐related vs. drug‐unrelated cues) in MUD patients with an f1 score of 90% on an out‐of‐sample testing set. The decreases of EEG between drug‐related cues and drug‐unrelated cues in delta, theta and alpha frequency bands are more frequently seen in patients than in healthy controls, perhaps reflecting general arousal and attenuated impulsive control. Our results suggest that EEG responses elicited by long‐duration methamphetamine‐related VR cues showed a specific signature, which may have future clinical implications.
What do geriatricians think about Comprehensive Geriatric Assessment? A survey of Australian and New Zealand geriatricians
Authors: Fox Sarah , Reid Natasha , Gordon Emily H. , Janda Monika , Hubbard Ruth E. 
Published: November 2022

AbstractObjectiveDespite Comprehensive Geriatric Assessment (CGA) being central to the work of geriatricians, little is known about geriatricians' views on CGA. This study was designed to understand how geriatricians conceptualise and practise CGA, and whether differences exist between groups (more experienced geriatricians vs. less experienced geriatricians and registrars; those practising in rural vs. metropolitan environments; in private vs. public sectors).MethodsAn anonymous 90‐item electronic questionnaire was emailed to members of the Australian and New Zealand Society for Geriatric Medicine.ResultsThere were 243 respondents (response rate 19%). Respondents stated that core features of CGA were multidimensional assessment (89%), implementation of a management plan (84%), and involvement of a geriatrician (70%). Important features in predicting CGA success were ability to implement health management recommendations (55%), and ease of communication with general practitioners (46%), and with the multidisciplinary team (45%). Functional decline (88%) and frailty (88%) were thought to predict patients likely to benefit from CGA, compared to age (48%) or multimorbidity (19%). Junior consultants and registrars were less likely to prioritise the importance of clinical leadership (10% vs. 30%), and more likely to report the importance of a structured format (17% vs. 7%) to CGA effectiveness.ConclusionsThere was some agreement about the core features of CGA and who is likely to benefit, but little agreement on features that predict CGA success. Further research that explores these points of difference would be helpful.
Quantification of the internal mammary artery size in Aboriginal and Torres Strait islanders
Authors: Knox Abbey , Gimpel Damian , Lance David , Rice Gregory D. , Crouch Gareth , Newland Richard F. , Baker Robert A. , Bennetts Jayme S. 
Published: November 2022

AbstractBackgroundVariation in size of the internal mammary artery has been demonstrated in ethnic groups, but not reported in Aboriginal patients. We hypothesised that the left internal mammary artery is smaller in Aboriginal patients compared to non‐Aboriginal patients and aimed to determine the impact on survival following coronary artery bypass graft (CABG) surgery.MethodsLeft internal mammary artery size was compared between Aboriginal (n = 345) and non‐Aboriginal (n = 1819) in 2343 patients undergoing CABG at Flinders Medical Centre from January 2010 to June 2021. To determine the association with‐survival we used Kaplan–Meier survival analysis and Cox proportional hazard models adjusted for preoperative variables.ResultsThere was a significant difference in left internal mammary artery (LIMA) size—Aboriginal 1.8 ± 0.4 mm; non‐Aboriginal 2.1 ± 0.4 mm (P < 0.001)—and left anterior descending (LAD) artery size—Aboriginal 1.7 ± 0.3 mm; non‐Aboriginal 1.9 ± 0.3 mm (P < 0.001). Aboriginal patients were more likely to have the LIMA discarded (9.3% vs. 0.4%) and to receive a LAD vein graft (17% versus 3%) (P < 0.001). There was no difference in 30‐day mortality or survival <5 years.ConclusionThis study supports the hypothesis that the left internal mammary artery is smaller in Aboriginal patients compared to non‐Aboriginal patients. Although Aboriginal patients were more likely to receive a venous conduit to the LAD, we observed no difference in survival up to 5 years. This data contrasts with reported outcomes of other ethnic groups.
Climate change education in the South Pacific: Resilience for whom?
Authors: Takinana Anuantaeka , Baars Roger C. 
Published: November 2022

AbstractClimate change education (CCE) can be an important tool to increase local community resilience. In 2017, the Pacific Community ratified the Framework for Resilient Development in the Pacific (FRDP) aiming to equip local communities with skills needed to become more climate change resilient. In 2018, Fiji implemented the Climate Change Resilience Programme (CCRP) at the University of the South Pacific (USP), the first of its kind in the South Pacific. This paper evaluates (i) the orientation and aim of the programme and (ii) how different stakeholders influenced the curriculum development process. Tribe's concept of curriculum space is used to highlight the overall aim of the CCRP. Freeman's stakeholder theory allows to identify key stakeholders and their influence on the curriculum. Results indicate that the programme seems to foster climate resilience in the workplace rather than the local community. Unfortunately, current and future community leaders, the notional targets of this course, were almost completely unrepresented in the process to accredit the course, with the body responsible for accreditation being dominated by industry representatives. This study helps to inform the current review of the Regional Certificate Programme to realign it with its initially envisioned community focus.