bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cost Optimization of Queueing System with Working Vacation, Setup, Feedback, Reneging, and Retention of Reneged Customers
Authors: Gupta R. 
Published: June 2022

In this manuscript, Markovian queueing system with working vacation, Bernoulli schedule interruption, setup time under feedback, reneging of impatient customers, and retention of reneged customers are analyzed. The unsatisfied customers on service completion may either leave the system with probabilities or may rejoin the queue with complementary probabilities during working vacations and regular service, respectively. The waiting customers in the queue may lose patience due to vacations and decide to leave without getting the service with probability q. They may be retained in the system via some convincing mechanisms with probability (1-q). The mean system length, probability of server in various states, mean sojourn time are obtained using the probability generating function method. The MATLAB software is used for representing the observed behavior graphically.
C -reactive protein in assessment of severity acute pancreatitis
Authors: Lslam Kazi Mazharul , Lslam Md Aminul , Bhuiyan Mashfique Ahmed , Muyaz Azizur Rahman , Masum Mohammad 
Published: June 2022

Background: Acute pancreatitis (AP) is an acute inflammation of the pancreas and clinical evolution is frequently unpredictable. Numerous predictive markers have been studied to assess severity in AP, including clinical assessment, clinical-physiological scoring systems, imaging techniques, and biochemical markers in different body fluids.
Objective: This study was done to see the association between level of CRP and severity of acute pancreatitis. Methods: 50 patients diagnosed as acute pancreatitis based on operational definition admitted in Dhaka Medical College Hospital was included in the study. Patients' admission date back from 1ST August, 2016 to 31december, 2015. Conservative management started from the date of admission as per standard conservative management protocol. Patients were monitored by RANSON scoring system and categorized as mild if RANSON score is <3 and categorized as severe if the score is ≥3. At the same time serum CRP level was measured on day 2, 3 and 7. Then the correlation between the severity of the disease and measures of CRP was established by unpaired t test and x2 test.
Results: Over 6 months of study period 50 patients were treated for pancreatitis in different medical and surgical unit of Dhaka Medical College Hospital. Etiological analysis revealed mostly caused by biliary disease (40%) followed by idiopathic, alcoholic, post ERCP and post traumatic. Based on RANSON score about 34 patient developed mild acute pancreatitis and 16 patient developed severe acute pancreatitis. Then CRP value of this two groups was compared on day 2, 3, 7 by unpaired t test with P value<.001 in all 3 days. ROC curve was plotted to determine specificity and sensitivity with a cut off value of CRP 132mg/l. Sensitivity and specificity was 75% and 55.8% accordingly. Conclusion: In a patient with acute pancreatitis the use of RANSON scoring system is not always possible as many of the investigation are not easily available in our set up. In our study we have found that serum CRP level is significantly (cut off value 132) higher in patient with sever acute pancreatitis. This will allow high proportion of patients with mild disease to be managed in low-cost hospital beds. Acute pancreatitis is an important cause of hospital admission with acute abdomen. It is responsible for significant morbidity and also mortality in patients
Journal of Surgical Sciences (2017) Vol. 21 (2): 80-84
Bioactivity evaluation of commercial root samples of Hemidesmus indicus (L.) R.Br.
Authors: Ferdouse Fatima , Mubassara Sanzida , Ahmed Fakhruddin Ali 
Published: June 2022

Four commercial root samples (CS1, CS2, CS3 and CS4) of Hemidesmus indicus alongside an authentic sample (HI) were evaluated following antibacterial potential, cytototoxicity and DPPH free radical scavenging activity assay. The inhibition zones produced by commercial samples ranged between 9.5 to 13.5 mm against the tested bacteria in antibacterial sensitivity test. HI produced highest inhibition zone recorded as 20.63 mm against Staphylococcus aureus followed by 17.4 mm against Bacillus subtilis at 150 μg/ml concentration. HI also showed highest cytotoxicity with LC50 value of 1.726 mg/ml, 4.754 mg/ml and 13.247 mg/ml after 6 hours, 12 hours and 24 hours respectively in brine shrimp lethality assay. Sample CS1 and CS2 showed less cytotoxicity compared to CS3 and CS4. Depending on the concentration of extracts, the DPPH free radical scavenging activities of commercial samples were in close proximity with HI. The total phenolic content in HI was 54.52 mg/ml while in four commercial sample, it ranged between 52.28 to 75.37 mg/ml gallic acid equivalent (GAE) per 100 mg extract.
Jahangirnagar University J. Biol. Sci. 8(2): 61-69, 2019 (December)
Effects of citric acid and gamma radiation on the shelf life of Labeo bata (Hamilton, 1822)
Authors: Kamrunnahar - , Haque Md Enamul , Hossain Arzina , Islam Mahfuza , Munshi Md Kamruzzaman , Asaduzzaman Khandoker , Huque Roksana 
Published: June 2022

The effects of citric acid (2%) and gamma radiation (1.0 and 1.5 kGy) on the quality and shelf life extension of Bata, Labeo bata (Hamilton, 1822) stored at refrigerated temperature (4°C) for 28 days were examined. Quality assessment were made by sensory (organoleptic scores), chemical (TV) and microbiological (TBC and TCC) evaluations. Organoleptic evaluation showed that irradiated samples were more acceptable than control and citric acid treated samples which also remained acceptable upto 28 days. TV of fish muscles increased with the increase of storage periods in all the samples. The rate of increase was lower in citric acid treated samples and the lowest was observed in samples with 1.5 kGy irradiation. Irradiated samples showed the best results in microbiological assessment. Gamma radiation in combination with low temperature (4°C) could increase the shelf life, and this technique may be applied for other fish species preservation.
Jahangirnagar University J. Biol. Sci. 8(2): 25-33, 2019 (December)
Pattern of haematological malignancies among patients attending at the haematology department in a tertiary hospital
Authors: Hasan Md Maruf Al , Sharmin Mahbuba , Kabir ASM Anwarul , Ferdous Jannatul , Khan MA , Hassan Md Kamrul , Farhad Mohammad Nurul , Nourin Tamanna 
Published: June 2022

Background : Hematological malignancies (HM) was comprise approximately 6.5% of all cancer incidences worldwide in 2012. Although prevalence of these malignancies are much lower in Asia and Africa then in Western countries. The incidence of these malignancies is drastically increasing in low-income settings. WHO predicts that the number of bloodrelated cancer cases would be increased about 48% in less developed countries by 2030 as compared to 2012.
Objective : In our study we tried to determine the current pattern of haematological malignancies among patients attending at the haematology department in a tertiary hospital.
Methods : This cross-sectional observational study was carried out in outpatients and inpatients department of Haematology, Dhaka Medical College Hospital, Dhaka from 13th August 2016 to 12th august 2017 for a duration of 12 months. Detail clinical history, examination findings and investigations of patients were recorded in a pre-designed case record form. All data were converted to tabulated forms to obtain statistical information by Using Microsoft Excel and SPSS 17 program.
Results : Out of 400 HM patients, most of them were male (66.75%) and remaining (33.25%) were female and male female ratio was 2.01:1. From rural were (71.25%) and remaining (28.75%) were urban population. Acute lymphoblastic leukaemia (ALL) patients were 87 (21.75%), mean age 25.4 years; Acute myeloid leukaemia (AML) patients were 81 (20.25%), mean age 36.5 years; Chronic myeloid leukaemia (CML) patients were 71 (17.75%), mean age 35.5 years; Non Hodgekin lymphoma (NHL) patients were 56 (14%), mean age 42.9 years; Acute promyelocytic leukaemia (APL) patients were 35 (8.75%), mean age 29.4 years; Multiple myeloma (MM) patients were 33 (8.25%), mean age 55.9 years; Hodgekin lymphoma (HL) patients were 24 (6.00%), mean age 33.8 years; Chronic lymphocytic leukaemia (CLL) patients were 7 (1.75%), mean age 61.9 years; Follicular lymphoma (FL) patients were 4 (1.00%), mean age 56.5 years; Mantle cell lymphoma (MCL) patient was 1 (0.25%), age 70 years and Burkitt lymphoma (BL) patient was 1 (0.25%), age 25 years.
Conclusion : Study result showed that acute leukaemias were more common than chronic cases. AML and APL (subtype of AML) were more than ALL. Individually APL was the 5th in position whereas ALL was the 1st and AML was the 2nd highest cases among the 11 types of HM found in this study. Percentage of CML was higher (3rd in position) than CLL (8th in position) among the studied cases. Among the lymphomas NHL was more common (4th in position) than HL (7th in position) and MM (6th in position). FL (subtype of NHL) which is low grade in nature was 9th in position among the eleven. MCL and BL was rare and each was 1 in number in this study.
Northern International Medical College Journal Vol. 11 No. 1 July 2019, Page 415-418
Serum uric acid level between normotensive and pre-eclamptic patients in third trimester of pregnancy and perinatal outcome
Authors: Nesa Fazilatun , Chowdhury Fahmida , Yasmeen BH Nazma , Begum Nasreen , Das Aparna 
Published: June 2022

Background : Preeclampsia is associated with maternal and neonatal complications. It has been indicated that increased uric acid might have a predictive role on preeclampsia. Several studies have demonstrated a relation between elevated maternal serum uric acid levels and adverse maternal and fetal outcome. The aim of this study was to find out the association of serum uric acid level between normotensive and pre-eclamptic (PE) patients in third trimester of pregnancy and perinatal outcome.
Methodology : A case control study was conducted in the department of the Obstetrics and Gynaecology in Dhaka Medical College Hospital from July 2017 to June 2018. A total number of 100 pregnant women in third trimester of pregnancy attending in Obstetrics and Gynaecology department of Dhaka Medical College Hospital were selected purposively as study subjects. Among them 50 diagnosed cases of preeclampsia were selected as cases with age range of 18-35 years and 50 normal healthy age matched pregnant women as controls. Pregnant women with pre-existing hypertension, diabetes mellitus and renal disease were excluded from the study by history, clinical examination and relevant laboratory investigations.
Results : The mean serum uric acid level was found 4.49±1.72 mg/dl in normotensive group and 7.03±1.89 mg/dl in preeclampsia group. Serum uric acid was significantly higher (p<0.05) in pre-eclampsia group than normotensive group. Regarding outcome take home as alive neonate was found 48(96.0%) in normotensive group and 41(82.0%) in preeclampsia group. Early neonatal death was 1(2.0%) in normotensive and 4(8.0%) in pre-eclampsia group. Still birth was 1(2.0%) and 5(10.0%) in normotensive and pre-eclampsia group respectively.
Conclusion : Hyperuricemia is most basic and reliable observations in pre-eclamptic pregnancies. While elevated concentrations of circulating uric acid are not uniformly increased in every woman with PE. But hyperuricemia is found in a subset of pre-eclamptic women who had higher risk for maternal and fetal complications. Therefore, measurement of serum uric acid concentration seems to be a useful test to predict maternal and fetal complications in a women with preeclampsia.
Northern International Medical College Journal Vol. 11 No. 1 July 2019, Page 419-422
Assessment of left Ventricular Longitudinal Function in Different Hypertensive Left Ventricular Geometry
Authors: Tareq Md Nur Uddin , Ahmed Chaudhury Meshkat , Mahmud Sohel , Haque KMHS Sirajul 
Published: June 2022

Background: Hypertension remains as the major risk factor for cardiovascular diseases. Hypertensive left ventricular hypertrophy was shown to be associated with increased morbidity and mortality. Left ventricular radial function (Ejection fraction) tends to remain normal in hypertensive patients, particular attention should be given to longitudinal function along with diastolic function. Left ventricular longitudinal function may vary across different hypertensive LV geometry with different prognosis.
Results: Of the total 214 study subjects, 109 (50.9%) were Cases and 105 (49.1%) were Controls. The mean ages of cases and controls were 52.66 (± 10.96) and 50.21 (± 10.91) years respectively. Left ventricular ejection function (LVEF) was almost identical in both groups [mean LVEF in case 68.7 % (± 6.9) Vs control 68.7(± 5.4), (p 0.947)]. Among the cases 43% had concentric hypertrophy (CH), 20% had eccentric hypertrophy (EH), 20% had concentric remodeling (CR), while normal geometry constituted the least 16.5%. Mean systolic mitral annular velocity (Vs) and mean early diastolic velocity (Ve) assesed by pulse wave tissue doppler imaging were observed to be significantly decreased in cases compared to their control counterpart (11.46 ± 1.26 vs. 15.41 ± 1.00 cm/sec, p < 0.001 and 13.80 ± 2.37 vs. 16.76 ± 2.67 cm/sec, p < 0.001. There was significant reduction of Vs in concentric hypertrophy and eccentric hypertrophy (11.31 ± 1.41 and 12.27 ± 2.14). (p <0.001 and <0.005). Among cases 55 (50.5%) and among controls 17 (16%) had diastolic dysfunction. Mean systolic mitral annular velocity (Vs) in patients with diastolic dysfunction (12.42 ± 1.90 cm/sec) was significantly lower than that in patients without diastolic dysfunction (13.86 ± 2.30 cm/sec) (p < 0.001).
Conclusion: Radial function (LVEF) remains normal in patients with systemic hypertension as compared to controls. LVH is common among hypertensive and concentric hypertrophy is the commonest geometry. LV longitudinal systolic function as assessed by systolic mitral annular velocity (Vs) by DTI was significantly reduced in hypertensives and CH is the most severely affected with EH at intermediate risk. Diastolic dysfunction is also common but almost alaways accompanied by impairment of LV longitudinal systolic function.
University Heart Journal Vol. 17, No. 1, Jan 2021; 31-37
Echocardiographic Assessment of the Effect of Mitral Stenosis Severity on Left Ventricular Systolic Function Using Isololumic Myocardial Acceleration
Authors: Islam Md Hasanul , Adhikary Dipal Krishna , Parvin Tanjima , Barman Rabindra Nath , Rahman Mahbubur , Sultan Md Ashraf Uddin , Chowdhury MSI Tipu , Hoque Md Harisul 
Published: June 2022

Background: Isovolumic myocardial acceleration (IVA) is a new tissue Doppler parameter in the assessment of systolic function of both right and left ventricles. It remains unaffected with the changes in pre-and after load with in the physiological range. With the advent of newer parameter like IVA, better assessment are naturally expected. Thus it creates a fertile ground where upon many studies are being done as it chosen here. The aim of study was to assess the effect of MS severety on LV systolic function using IVA.
Methods: In this cross sectional study, considering all ethical issues, data were collected from 96 patient (Isolated mitral stenosis and mitral valve area <2cm2) and 32 healthy control subjects. In addition to standard echocardiographic methods TDI (tissue Doppler imaging) were performed to assess LV function in all participants.
Results: This study showed a clear female preponderence (76%) of mitral stenosis and most of them belonging to age group 21-39 years. All TDI derived LV systolic (IVV, Sm and IVA) velocities were significanty decreased in patients with mitral stenosis, compared to the healthy control (P<.001, for all). However IVA was not different when the degree of MS was evaluated (P=.056). In addition IVA was not correlated with MVA (r=+0.196. P= 0.056).
Conclusions: Isovolumic myocardial acceleration was more accurate and consistent than conventional echocardiography in assessing subclinical left ventricular systolic dysfunction, IVA showed that left ventricular function is impaired with mitral stenosis regardless of severety of the disease. So this new echo parameter can be a good supplement to the existing 2D scoring system to detect systolic dysfunction in rheumatic mitral stenosis.
University Heart Journal Vol. 17, No. 1, Jan 2021; 42-46
Angiographic Studies of Coronary Artery Disease in Rangpur Medical College Hospital
Authors: Islam Md Hasanul , Ghafur Shakil , Barman Rabindra Nath , Sarker Haripada , Basunia Abu Zahid , Rahman Mahbubur , Mahmud Abdullah Al 
Published: June 2022

Background: Coronary artery disease (CAD), one of the leading causes of death is increasing globally. The number of CAD is also increasing in Bangladesh. Rangpur Medical College & Hospital is also providing cardiovascular services to populations from urban, semiurban and rural population of northern region of the country. It started coronary angiography services from June 2011. This paper aims to analyze pattern of coronary artery occlusion in patients undergoing coronary angiography during January to October 2019.
Methods: This was a retrospective observational study conducted in the cardiology department. There were a total of 308 cases of diagnostic angiography and coronary interventions done in Rangpur Medical College & Hospital from January to October 2019. Among them 308 cases of coronary angiography done for Acute Coronary Syndrome and Stable Angina, were analyzed using SPSS (Statistical Package for Social Science), version 17.
Results: Males were higher in number than females and majority of the patients were at or above 50 years of age. Out of 308 cases 225 had Acute Coronary Syndrome (ACS) and 83 had Stable Angina. 54 out of 308 were found to have normal coronaries. 25 patient with ACS had normal coronary. Out of all the patients with coronary stenosis, 19 had left main disease, 59 had SVD, 62 has DVD, 71 patient had TVD. 9 patients had CTO. 159 patients had severe coronary stenosis. 117 out of 225 ACS patient had more than one coronary artery involved, which is significantly higher than the stable angina group ( p<0.01). Severe stenosis was found to be more common in ACS group (p<0.003) when compared to the stable angina group.
Conclusion: There has been a change with regard to clinical presentation and onset of risk factors for CAD at young age, but the load of atherosclerotic burden and pattern of involvement of coronary arteries have not changed in Elder group. Coronary angiography is a useful diagnostic and therapeutic tool for CAD. Coronary status is significantly different in ACS and stable angina. ACS has more chance of having multivessel stenosis whereas stable angina has single vessel, less severe or normal coronaries. Severity of stenosis is also high in ACS than in stable angina.
University Heart Journal Vol. 17, No. 1, Jan 2021; 55-59
The Effect of Tai Chi Exercise on Reduction the Risk of Falls in the Elderly: A Literature Review
Authors: Mar'ah Novya Ashlahatul , Sartika Aprilina , Jannah Eka Sindi Miftahul , Suryani Neni , Wahyudi Dheni , Pulungan Rodiah , Permata Rhury Nia , Anwar Syamsul 
Published: June 2022

The risk of falls in the elderly increases with age. Even though there are many complications that occur if the elderly fall, Tai Chi exercise is one of the best fall prevention exercises, compared to other exercise programs that focus on muscle strength.
Aims: This study aims to summarize studies on the effectiveness of Tai Chi Exercises to reduce falls in the elderly.
Methods: a literature review using three databases (Pubmed, Google Scholar, and Sciendirect) for previous studies published from 2017 to 2022. The CASP format PRISMA guidelines and the PICOT framework were used to assess study quality assist in article selection, and define criteria—research inclusion.
Results: A total of 5 articles from 65 studies were included in the review process. The results showed that Tai Chi exercise significantly reduced the risk and fear of falling in the elderly. The gentle and coordinated Tai Chi movements can increase the flexibility of the lower extremities. Conclusion: Tai Chi exercise can be ascertained as an activity for healthy elderly has many benefits, mainly to prevent the risk of falling.
Individualized Analysis and Treatment of Difficult Weaning From Ventilation Following Open Cardiac Surgery in Young Children With Congenital Heart Disease
Authors: Wu Xiaoming , Chen Jinlan , Iroegbu Chukwuemeka Daniel , Liu Jian , Wu Ming , Xie Xia , Xiang Kun , Wu Xun , Chen Wangping , Huang Peng , Zhou Wenwu , Fan Chengming , Yang Jinfu 
Published: June 2022

AimsThe study explores the leading causes of postoperative extubation difficulties in pediatric patients (neonates and toddlers) with congenital heart diseases and establishes individualized treatment for different reasons.MethodWe retrospectively analyzed medical records of 4,971 pediatric patients with congenital heart defects treated in three tertiary Congenital Heart Disease Centres in China from January 2005 to December 2020, from whom we selected those with difficulty extubation but successful weaning during the postoperative period. Next, we performed an analysis of risk factors and reported the combined experience of individualized treatment for successful extubation.ResultsSeventy-five pediatric patients were identified in our database, among whom 23 had airway stenosis, 17 had diaphragmatic dysfunction, and 35 had pulmonary infection. The patients were all successfully weaned from the ventilator after an individualized treatment plan. In addition, the intubation time in the airway stenosis group was 17.7 ± 9.0, 33.6 ± 13.9 days in the diaphragmatic dysfunction group, and 11.9 ± 3.8 days in the pulmonary infection group.ConclusionGiven the primary reasons for difficult weaning following open-heart surgery in pediatric patients with congenital heart diseases, an individualized treatment scheme can achieve the ideal therapeutic effect where patients can be weaned faster with a shorter intubation period.