bluuebunny/crossref_metadata_2025_split huggingface dataset:
An individually-controlled multi-tined expandable electrode using active-cannula-based shape morphing for on-demand conformal radiofrequency ablation lesions
Authors: Chai Zhiping , Lyu Liangxiong , Pu Menghao , Liang Huageng , Ding Han , Wu Zhigang 
Published: January 2022

Being minimally invasive and highly effective, radiofrequency ablation
(RFA) is widely used for small size malignant tumors treatment. However,
in clinical practice, a large number of tumors are found in irregular
shape, while the current RFA devices are hard to control their
morphologic appearance of RFA lesions on demand, which usually ends up
excessively ablating the tissues and often brings excessively
irreversible damage to the organs’ functions. Here, we introduce active
cannulas for each of individually-controlled sub-electrodes to achieve
an on-demand shape morphing and thus conformal RFA lesion. The shape as
well as the length of inserted sub-electrode can be precisely controlled
by tuning the expanded length of the active stylet and relative position
of the active cannula. Furthermore, owing to independent movement and
energy control of each sub-electrodes, our electrode is shown to be not
only efficient enough to accomplish accurate trajectory to target tissue
in a single insertion, but also adaptive enough to ablate target tissues
with diverse morphologic appearances and locations. Potentially, our RFA
electrode is a better choice in the future clinical practice for
minimally invasive treatments of malignant tumors of which preferred
treatment is conformal ablation.

Corresponding author(s) Email: zgwu@hust.edu.cn
The Experience of Health Care Workers Infected by Corona Virus Diseases-19
Authors: Rochanah Siti , Nurbaeti Irma 
Published: January 2022

Background. The number of healthcare workers in front line has affected by COVID-19 and some of them infected by COVID-19 since COVID-19 outbreak. Understanding healthcare workers experience is important to get their meaning and expression. Purpose. The purpose this study was to explore the experiences of health workers infected by COVID-19. Methods. A Qualitative phenomenological approach was carried out in this study with phenomenological analysis for interpretation data. Data were collected using in-depth interviews of 12 health workers who were infected by COVID-19 either during their treatment or after being treated at non-government hospital in Jakarta, Indonesia. Results. We found five themes followed by fourteen subthemes. The themes were (1) The meaning of COVID-19 for her/his self, (2) The first feelings of being infected with COVID-19, (3) Experience of Clinical symptoms, (4) Experience of psychological and social disorders, (5) Experience in accessing health services. Conclusions. Health workers who infected by COVID-19 had some positive and negative experience. This research may provide a deep understanding about the life of health workers infected by COVID-19. Proper planning and support are important to reduce health workers’ problems both physical and psychological.
Female gender and mortality in ST-segment-elevation myocardial infarction treated with primary PCI
Authors: Paradossi Umberto , Taglieri Nevio , Massarelli Giulia , Palmieri Cataldo , De Caterina Alberto Ranieri , Bruno Antonio Giulio , Taddei Alessandro , Nardi Elena , Ghetti Gabriele , Palmerini Tullio , Trianni Giuseppe , Mazzone Annamaria , Pizzi Carmine , Donati Francesco , Bendandi Francesco , Marrozzini Cinzia , Ravani Marcello , Galiè Nazzareno , Saia Francesco , Berti Sergio 
Published: January 2022

Aims
To investigate gender difference in mortality among patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous angioplasty (PPCI).

Methods
We analyzed data from the prospective registries of two hub PPCI centres over a 10-year period to assess the role of female gender as an independent predictor of both all-cause and cardiac death at 30 days and 1 year. To account for all confounding variables, a propensity score (PS)-adjusted multivariable Cox regression model and a PS-matched comparison between the male and female were used.

Results
Among 4370 consecutive STEMI patients treated with PPCI at participating centres, 1188 (27.2%) were women. The survival rate at 30 days and 1 year were significantly lower in women (Log-rank P-value < 0.001). At PS-adjusted multivariable Cox regression analysis, female gender was independently associated with an increased risk of 30-day all-cause death [hazard ratio (HR) = 2.09; 95% confidence interval (CI): 1.45–3.01, P < 0.001], 30-day cardiac death (HR = 2.03;95% CI:1.41–2.93, P < 0.001), 1-year all-cause death (HR = 1.45; 95% CI:1.16–1.82, P < 0.001) and 1-year cardiac death (HR = 1.51; 95% CI:1.15–1.97, P < 0.001). For the study outcome, we found a significant interaction of gender with the multivessel disease in females who were at increased risk of mortality in comparison with men in absence of multivessel disease. After the PS matching procedure, a subset of 2074 patients were identified. Women still had a lower survival rate and survival free from cardiac death rate both at 30-day and at 1-year follow-up.

Conclusion
As compared with men, women with STEMI treated with PPCI have higher risk of both all-cause death and cardiac mortality at 30-day and 1-year follow-up.
Litíase em Rim em Ferradura em Doente com Ureter Reimplantado: A Propósito de um Caso Clínico
Authors: Nunes-Carneiro Diogo , Oliveira Rui , Cavadas Vítor 
Published: January 2022

O rim em ferradura é uma anomalia renal congénita muito comum, estando muitas vezes associada a infeções do trato urinário e a litíase renal como consequência das alterações anatómicas que dificultam uma drenagem eficaz de urina. O tratamento dos cálculos nestes casos torna-se um desafio devido às anomalias anatómicas subjacentes exigindo uma adaptação das técnicas normalmente utilizadas para o tratamento da litíase renal.
O artigo reporta o caso de uma mulher de 44 anos, com uma história de reimplantação ureteral à esquerda do tipo Cohen por refluxo vesico-ureteral na infância e com litíase renal. A doente apresentava dois cálculos com 12 e 10 mm de maior diâmetro no pielão superior do hemi-rim esquerdo, cujo infundíbulo tinha um calibre estreito. Procedeu-se a uma ureterorrenoscopia flexível com litotrícia laser Holmium através da colocação de uma baínha ureteral acima do infundíbulo estreitado tendo a doente ficado sem cálculos no final do procedimento.
Torna-se importante, nos casos de litíase em rim em ferradura, pensar e adaptar as várias técnicas disponíveis para o tratamento da litíase renal e eleger aquela que, à partida, proporcionará uma maior taxa de sucesso com menos complicações.
Novas Técnicas Endoscópicas de Diagnóstico do Carcinoma Urotelial do Trato Urinário Superior
Authors: Vieira Maria Teresa , Cavadas Vítor 
Published: January 2022

O carcinoma urotelial do trato superior (CUTS) é raro, mas a maioria dos casos apresenta-se invasiva ao diagnóstico. O tratamento padrão do CUTS consiste na nefroureterectomia radical. No entanto, os CUTS de baixo risco podem ser abordados com cirurgia poupadora de nefrónios (CPN), sem compromisso do prognóstico oncológico. As técnicas de diagnóstico atuais apresentam várias falhas no diagnóstico de CUTS, principalmente na deteção de carcinoma in situ (CIS), uma lesão plana, de alto grau e com elevado risco de progressão. Assim, torna-se pertinente a investigação de novas técnicas de diagnóstico capazes de detetar as lesões de CUTS numa fase mais precoce.
Esta revisão procura analisar o desempenho das novas técnicas de imagem disponíveis para o diagnóstico do CUTS. Foi conduzida uma pesquisa da literatura atual na base de dados PubMed e foram revistos artigos sobre a narrow band imaging (NBI), Image1 S, diagnóstico fotodinâmico (DFD), confocal laser endomicroscopy (CLE) e optical coherence tomography (OCT).
Foram selecionados seis artigos para revisão, todos referentes a estudos in vivo em humanos. Não foi encontrado nenhum artigo sobre o Image1 S. Todas as técnicas descritas são compatíveis com os ureterorrenoscópios flexíveis atuais. A NBI, o Image1 S e o DFD visam uma melhor deteção do CUTS. A CLE e a OCT visam a caracterização histopatológica e minimamente invasiva das lesões, em tempo real. Quer a NBI, quer o DFD apresentam melhor taxa de deteção das lesões em comparação com a ureterorrenoscopia flexível (URSF) convencional, mas apenas o DFD mostrou melhor deteção de CIS. A CLE permite distinguir o urotélio saudável do maligno e as lesões de baixo grau das de alto grau. No entanto, não avalia o estadiamento. A OCT apresenta maior sensibilidade do que a biópsia para o estadiamento e gradação do CUTS, mas as lesões com mais de 2 mm de espessura podem gerar diagnósticos falsos-positivos.
A combinação da URSF com uma ou várias das novas técnicas de diagnóstico poderia aumentar a sua precisão diagnóstica e capacidade de selecionar adequadamente os candidatos para CPN. São necessários mais estudos que validem a utilização das novas técnicas no diagnóstico de CUTS.
Hemichorea induced by a sphenoid ridge meningioma
Authors: Inoue Hirotaka , Yamamura Rihito , Yamada Kazumichi , Hamasaki Tadashi , Inoue Nobuhiro , Mukasa Akitake 
Published: January 2022

Background:
Movement disorders are rare in brain tumors. We describe a 45-year-old woman with hemichorea, a concomitant contralateral sphenoid ridge meningioma.

Case Description:
The meningioma enlarged as her hemichorea worsened, and after meningioma resection, the hemichorea gradually subsided. N-isopropyl-p-[123I]-iodoamphetamine single-photon emission computed tomography performed preoperatively showed decreased regional cerebral blood flow (CBF) to the basal ganglia circuit ipsilateral to the tumor and, when repeated postoperatively, confirmed improved regional CBF.

Conclusion:
We propose that the enlarging sphenoid ridge meningioma had a remote effect on regional CBF and the thalamocortical motor center and that complex changes in the basal ganglia output may have caused the hemichorea.
Multiple cerebral hemorrhages in sepsis-disseminated intravascular coagulation versus septic embolism: An image report
Authors: Akel Omar , Raju Bharath , Suresh Sumatha Channapatna , Jumah Fareed , Gupta Gaurav , Nanda Anil 
Published: January 2022

Background:
Septic emboli are commonly attributed to infective endocarditis and can present with a variety of symptoms including altered mental status and focal neurological deficits. Here, we reviewed images of septic emboli with hemorrhagic conversion in a patient with sepsis and a psoas abscess. We aim to show the classical image findings in septic embolism to brain, which is sparsely described in literature and the report differentiates the septic embolism from disseminated intravascular coagulation which can present with almost identical image findings.

Case Description:
A 53-year-old male patient who was operated on for a right inguinal hernia developed a postoperative wound infection 2 weeks after surgery and was started on IV antibiotics. Despite medical management, his infection did not improve, prompting a computed tomography (CT) scan which revealed a psoas abscess. The abscess was drained, and antibiotics continued. A few days later, he developed altered sensorium prompting a head CT which revealed septic emboli and hemorrhage at the gray-white junction. Cultures grew multidrug-resistant Escherichia coli; the patient was treated with IV tigecycline and improved over the following 4 weeks.

Conclusion:
In patients with a known ongoing infectious process with hemodynamic stability who develop altered mental status in the setting of a normal coagulation profile, D-dimer, positive blood cultures, and absent signs of multiorgan failure, a diagnosis of septic emboli should be entertained. Although CT can reveal macrobleeds, MRI is more sensitive in confirming cerebral microbleeds. Thus, patients in sepsis with unexplained altered sensorium should undergo an MRI of the brain to rule out septic emboli and microbleeds.
Effects of ketamine versus dexmedetomidine maintenance infusion in posterior spinal fusion surgery on acute postoperative pain
Authors: Nikoubakht Nasim , Alimian Mahzad , Faiz Seyed Hamid Reza , Derakhshan Pooya , Sadri Mohammad Saleh 
Published: January 2022

Background:
One of the most challenging issues after posterior spinal fusion (PSF) surgery is providing appropriate pain control measures to enhance recovery of the patients. We aimed to compare effects of ketamine versus dexmedetomidine infusion during maintenance of anesthesia on acute postoperative pain in PSF surgery.

Methods:
In a double-blinded randomized clinical trial, 87 patients candidates for PSF surgery were randomly assigned into three groups. Anesthesia protocol for all groups was the same except: the first group received 0.2 mcg/kg/h dexmedetomidine infusion, the second received 0.1 mg/kg/h ketamine infusion, and control group received normal saline infusion as a placebo. Pain intensity by VAS scale and level of sedation by Ramsey scale were assessed, and amount of opioid prescribed after surgery was measured and compared for patients during the recovery and at 2, 4, 6, 12, and 24 h after surgery in three groups, and hypotension and bradycardia during operation were reported.

Results:
There was a significant difference among the groups regarding pain intensity and amount of opioids during recovery and at 2, 4, 6, 12, and 24 h after surgery. Pain intensity and amount of opioids for ketamine and dexmedetomidine groups were significantly lower than those in the controls during recovery and at the hours after surgery. There was no significant difference regarding bradycardia and hypotension and level of sedation during recovery and at the hours after surgery.

Conclusion:
Both ketamine and dexmedetomidine infusions during maintenance of anesthesia are effective in reducing acute postoperative pain effectively after PSF surgery.
Tumefactive multiple sclerosis versus high-grade glioma: A diagnostic dilemma
Authors: French Heath David 
Published: January 2022

Background:
Tumefactive demyelinating lesions (TDLs) share similar clinical features and MRI characteristics with high-grade glioma (HGG). This study develops an approach to navigating this diagnostic dilemma, with significant treatment implications as the management of both entities is drastically different.

Methods:
A retrospective analysis of 41 TDLs and 91 HGG with respect to demographics, presentation, and classical MRI characteristics was performed. A diagnostic pathway was then developed to help diagnose TDLs based on whole neuraxis MRI and cerebrospinal fluid (CSF) examination.

Results:
The diagnosis of TDL is more likely than HGG in younger females who present with subacute or chronic symptoms. MRI characteristics favoring TDL over HGG include smaller size, open rim enhancement, little or no associated edema or mass effect, and the presence of a T2 hypointense rim. MRI of the whole neuraxis for detection of other lesions typical of multiple sclerosis (MS), in combination with a lumbar puncture (LP) showing positive CSF-specific oligoclonal bands (OCB), was positive in 90% of the TDL cohort.

Conclusion:
The diagnostic pathway, proposed on the basis of specific clinicoradiological features, should be followed in patients with suspected TDL. If MRI demonstrates other lesions typical of MS and LP demonstrates positive CSF-specific OCBs, then patients should undergo a short course of IV steroids to look for clinical improvement. Patients who continue to deteriorate, do not demonstrate other lesions on MRI or where the LP is negative for CSF-specific OCB, should be considered for biopsy if safe to do so. This pathway will give the patients the best chance at neurological preservation.
Identifying the influence of quality management of ISO 9001 on product innovation and financial turn over interfering the lack of peripheral confidence
Authors: Aghaei Ghaem , Dashtbozorg Mahmoud , Ahmadpour Maryam Bavarsad 
Published: January 2022

This paper aims at identifying the influence of Quality Management of ISO 9001 on product innovation and financial turn over interfering the lack of peripheral confidence. The population includes 90 employees of industrial factories around Ahvaz and in Ahvaz-Shooshtar road who were selected through random sampling. Stability and the validity of the mentioned questionnaire were also evaluated in this research. Data analysis was performed via descriptive and inferential analysis and also SPSS18 and Lisrel 8.5 and approved by confirmatory factor and goodness of fit for four variables. The results coming from the hypothesis test confirm the both the hypothesis and the influence of ISO 9001 Quality Management on financial turn over and the innovation. Also the turn over itself is effective in product innovation but the inferential role of lack of peripheral confidence on ISO 9001 Quality Management on financial turnover and the product innovation was not approved.
Analyze and prioritize strategic factors on the establishment of knowledge management in banks
Authors: Shokrollahzade Farshad , Nasab Saeed Hakami 
Published: January 2022

Introduction: Knowledge management covers all process and activities related to the creation, acquisition sharing and use knowledge, skills and expertise. At the present of time, if organization does not have information and new knowledge in according with global development will not be able to make the right decision. Addressing the issue of knowledge and knowledge management it is important to have knowledge because knowledge is an ultimate competitive advantage for new origination and the key to victory and it is the only source that is difficult or even impossible to imitate and copy. Methods: This study is a descriptive survey. The study sample included all employees of Bank Hekmat Iranian are located in Tehran. According to the understanding of study population characteristics, simple random sampling method was used. In this study, on the framework Of Huang is studied: Team working, employee involvement, employee empowerment, knowledge structure, information system, training, commitment of senior management, benchmarking, performance measurement, organizational culture. The descriptive analysis of data using descriptive statistics and then through confirmatory factor analysis using SMART PLS software to inferential analysis of the hypothesis was done. Subsidiary hypothesis were studied and tested by One-Sample T-Test. Results: The analyze performed on collated data, it was concluded that all elements of employee empowerment, infrastructure , information systems, organization culture, modeling, employee involvement, teamwork, commitment of senior managers, knowledge structure, staff training and performance measurement leads to successful implementation of knowledge management in Bank Hekmant Iranian. Prioritizing these factors, as well as to establish knowledge management model led to 1. Team working, 2. Employee involvement., 3. Employee Empowerment, 4. Knowledge structure, 5. Information System, 6. Training, 7. Commitment of senior management, 8. Benchmarking, 9. Performance measurement, 10. Organizational culture. Results of the analysis showed that the situation of organizational culture, employee empowerment and information systems infrastructure are significantly appropriate, the situation of commitment of senior management, staff training, teamwork, benchmarking and structure knowledge and performance measurement are partly appropriate. Conclusion: Identifying factors affecting on successful implementation of knowledge management in Bank Hekmat Iranian may lead to identifying gaps in organizational knowledge, more productivity of human capital, efficient and effective learning of staff, providing more value-added services, customers and employees satisfaction, prevent the recurrence of errors, reduction duplication, saving time, stimulate motivation, creativity and innovation, and strengthening the competitive position of the bank.
Cinétique des interactions huile essentielle-antifongique
Authors: Alama Hakim El , Aissami Aicha El , Benmoussa Adnane , Said Amal Ait Haj , Arahou Moustapha , Alaoui-Faris Fatima-Ezzahra El 
Published: January 2022

L’objectif de ce travail, en plus de l’étude phyto-chimique et antifongique, est d’étudier la cinétique des interactions anti-candidosiques de l’huile essentielle (H.E) de Melaleuca alternifolia et de deux antifongiques : l'amphotéricine B (Amph B) et le fluconazole (Fluc). L’huile essentielle de Melaleuca alternifolia a été extraite des feuilles et des tiges terminales à l’aide d’un dispositif de type Clevenger, analysée par chromatographie en phase gazeuse couplée à la spectrométrie de masse. L’activité anti-candidosique a été évaluée selon deux techniques ; la technique de l’aromatogramme et la technique de microdilution. La souche microbienne est un lot de l’ATCC (American Type Culture Collection 90029) de Candida albicans. Le pourcentage et la zone d’inhibition, les concentrations minimales inhibitrices (CMI) et fongicides (CMF) et les indices de concentrations fractionnaires inhibitrices (ICFI) et fongicides (ICFF) ont été déterminés. Le rendement de l’extraction était de 1,98 %. Les composés majoritaires étaient : Le terpinène-4-ol (31,15 %), l’-terpinène (12,02 %) et le -terpinéol (8,12 %). Le diamètre d’inhibition de l’huile essentielle était de 24,52 ± 0,9 mm. Le taux d’inhibition de la pousse de Candida albicans était de 97,35 ± 2,16 %. On a noté une variation des valeurs des CMI et des CMF en fonction des concentrations d’association entre l’huile essentielle et les antifongiques étudiés. Les plus faibles valeurs des ICFI des associations H.E/Amph B et H.E/Fluc ont été respectivement 0,493 et 0,432, celles des ICFF ont été de l’ordre de 0,862 et 0,798. L’huile essentielle de Melaleuca alternifolia est un excellent fongicide. Son activité anti-candidosique majeure in vitro pourrait faire l’objet d’autres études plus soutenues in vivo afin d’enrichir l’arsenal antifongique tout en réduisant les effets médicamenteux indésirables.
Profiling Student Teachers Tendencies on Peer Review Production
Authors: Rahmawati Eva 
Published: January 2022

ABSTRACT This is a report of a preliminary study focused on investigating student teachers tendencies of peer review production. The research is a basis for a more comprehensive research aiming to explain how the aforementioned tendencies affect the effectiveness of peer review. The data collected were in the form of students written commentaries taken from three expository and argumentative essay writing assignments. These data were collected from eight students, four high achievers and four low achievers. On the courses first meeting, an essay writing proficiency test was administered to determine researchs participants and dyads involved. To prepare students with peer review practice, a peer review tutorial and rubrics were also given on the first meeting of the course. Following this stage, students written commentaries were collected as data, which were then codified following the typology of written feedback by experts. Codification results were interpreted by comparing them to previous related research. In doing so, it was apparent that low achievers tend to produce commentaries on surface structure errors. As oppose to this, organization and content-focused commentaries were dominant in high achievers feedbacks. These findings are noteworthy, as they suggest a link between students proficiency level and their preferred commentary focus.Keywords: academic writing, peer review production, student teacher, commentary provision tendency.