bluuebunny/crossref_metadata_2025_split huggingface dataset:
Configuration‐Dependent Liquid Crystal and Gel Behaviors of Tetraphenylethene‐Containing Main‐Chain Copolyesters
Authors: Wang Jing , Wang Tian , Jiang Qian , Zhang Yuping , Qiu Yuan , Wang Hong , Yin Guochuan , Liao Yonggui , Xie Xiaolin 
Published: May 2022

AbstractThe construction of aggregation‐induced emission‐active (AIE‐active) gelators with liquid crystal properties remains a challenge. Moreover, the effects of AIE configuration on liquid crystal, gel and AIE behaviors in one system are unclear. Herein, two main‐chain liquid crystalline copolyester gelators with a single configuration of AIEgen TPE, mesogen biphenyl, and pendent amide groups are synthesized through melt polycondensation. Both copolyesters display smectic phase, while E‐P20 possesses a wider temperature range of liquid crystal and a narrower layer distance owing to the more serious nonlinear “defect” of Z‐TPE than E‐TPE units. In addition, E‐P20 and Z‐P20 can form AIE‐active gels with the minimum gelation concentration (MGC) values of 10 and 4 wt% in ethyl acetate mainly via hydrogen bonds between the pendent amide groups, respectively. These AIE‐active gels show potential applications in temperature sensor, information storage, and so on.
Self‐Healing and Electrical Properties of Viscoelastic Polymer–Carbon Blends
Authors: Milkin Pavel , Danzer Michael , Ionov Leonid 
Published: May 2022

AbstractSelf‐healing polymer–carbon composites are seen as promising materials for future electronic devices, which must be able to restore not only their structural integrity but also electrical performance after cracking and wear. Despite multiple reports about self‐healing conductive elements, there is a lack of a broad fundamental understanding of correlation between viscoelasticity of such composites, their electrical properties, and self‐healing of their mechanical as well as electrical properties. Here, it is reported thorough investigation of electromechanical properties of blends of carbon black (CB) as conductive filler and viscoelastic polymers (polydimethylsiloxanes (PDMS) and polyborosiloxane (PBS)) with different relaxation times as matrices. It is shown that behavior of composites depends strongly on the viscoelastic properties of polymers. Low molecular polymer composite possesses high conductivity due to strong filler network formation, quick electrical, and mechanical properties restoration, but for this the ability is sacrificed to flow and ductility at large deformation (material is brittle). In contrary, high relaxation time polymer composite behaves elastically on small time and flows at large time scale due to weak filler network and can heal. However, the electrical properties are worse than that of carbon and viscous polymer and degrade with time.
The influence of roller burnishing process parameters on surface quality and fatigue life of AA 7075‐T6 alloy
Authors: Celik M. , Caydas U. , Akyuz M. 
Published: May 2022

AbstractRoller burnishing method is a low‐cost and effective surface treatment method that has been frequently preferred in recent years. In this method the surface roughness is minimized by small plastic deformations, without removing chips from the surfaces, caused by the rolling element pressed against the surface with a certain force. While the surface hardness of the material increases in the process, the surface roughness decreases significantly. In this study, the effects of the process parameters of roller burnishing method (burnishing pressure and number of passes) on AA7075‐T6 aluminum alloy in terms of fatigue strength and surface roughness were investigated experimentally. Taguchi L9 experimental design method was used in the study, and the burnishing process was carried out by a specially produced disc‐shaped apparatus. As a result of the study, it was determined that the roller burnishing method increased both the fatigue strength and surface quality of AA 7075 T6 alloy. In consequence of roller burnishing, it was determined that fatigue life and surface roughness values improved by 116 % and 96 %, respectively.
Plasma lncRNA LOC338963 and mRNA AP3B2 are upregulated in paraneoplastic Lambert‐Eaton myasthenic syndrome
Authors: Yang Fei , Jing Feng , Li Yang , Kong Shanshan , Zhang Shimin , Huo Yunyun , Huang Xusheng , Yu Shengyuan 
Published: May 2022

AbstractIntroduction/AimsLambert‐Eaton myasthenic syndrome (LEMS) is an autoimmune neuromuscular junction disorder. Long noncoding RNA (lncRNA) can regulate the expression of mRNA and is involved in the development of autoimmune diseases, but few genetic studies are available. In this study we aimed to explore the lncRNA and mRNA changes of LEMS.MethodsPlasma lncRNA and mRNA expression profiles of three LEMS patients with small cell lung cancer (SCLC) and three matched healthy controls were analyzed by microarray. Differentially expressed lncRNAs and adjacent mRNAs were jointly analyzed, and candidates were verified by quantitative real‐time polymerase chain reaction (qRT‐PCR). The identified genes were subsequently evaluated in 9, 8, and 4 patients with paraneoplastic LEMS, nontumor LEMS, and SCLC, respectively. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed to determine possible functions.ResultsA total of 320 lncRNA and 168 mRNAs were differentially expressed in the three LEMS with SCLC and compared with healthy controls. Among these, lncRNA LOC338963 and its neighboring mRNA AP3B2 were upregulated jointly, which was confirmed by qRT‐PCR. qRT‐PCR revealed significant upregulation of the two genes in patients with paraneoplastic LEMS compared with nontumor LEMS or SCLC. GO analysis of AP3B2 identified the enrichment terms anterograde synaptic vesicle transport and establishment of synaptic vesicle localization. KEEG analysis showed that AP3B2 was enriched in lysosomal pathways.DiscussionLOC338963 and AP3B2 were upregulated in patients with paraneoplastic LEMS, suggesting their involvement in pathogenesis. These genes could be targets for exploring the pathomechanism of paraneoplastic LEMS.
Relationship between the early repolarization pattern and a history of suicide attempts among drug‐free psychiatric patients
Authors: Kameyama Hiroshi , Sugimoto Kenichi , Kodaka Fumitoshi , Ito Kyoko , Nukariya Kazutaka , Kato Tomohiro , Shigeta Masahiro 
Published: May 2022

AbstractAimSuicide attempts are an important severe psychiatric symptom and a clear outcome for mental disorders. Although the relationship between the early repolarization pattern in electrocardiogram and psychiatric disorders has recently been reported, these reports have not been able to exclude the influence of psychiatric drugs. This study aimed to investigate the relationship between the early repolarization pattern and a history of suicide attempts among patients not receiving psychiatric medication.MethodsA total of 71 patients with a history of suicide attempts were investigated, 38 of whom were analyzed for this study. We compared the frequency of the early repolarization pattern between a suicide attempt group and a control group. Then, we investigated the association between the early repolarization pattern and the suicide attempt group by logistic regression analysis, including electrocardiographic findings associated with psychiatric disorders.ResultsThe findings indicated that the frequency of the early repolarization pattern was significantly higher in the suicide attempt group (n = 20; 52.6%) than in the control group (n = 4; 10.5%) (P < 0.001), and the results of the logistic regression analysis indicated that the early repolarization pattern was associated with suicide attempts.ConclusionsThese findings suggest that the early repolarization pattern is associated with a history of suicide attempts.
Inverse optimal control for positive impulsive systems toward personalized therapeutic regimens
Authors: Hernandez‐Vargas Esteban A. , Hernandez‐Mejia Gustavo , Hernandez‐Gonzalez Miguel 
Published: May 2022

AbstractInfectious diseases are latent threats to humankind. Control theoretical approaches can help practitioners to advance the scheduling of drugs. For the case of infectious diseases, it is not possible to keep continuous flow of drug administration over all time‐steps, thus the action of the control input has to be restricted at some of thekth instants. This paper presents the adaptation of inverse optimal control to positive impulsive systems in discrete‐time to schedule therapies. The properties of positive systems are used to simplify the control design. Thus, the problem of scheduling therapies in infectious diseases is illustrated with influenza and COVID‐19. Numerical results show the applicability of the control algorithms.
Electrospinning of spider silk‐based nanofibers
Authors: Yazawa Kenjiro , Mizukami Saeka , Aoki Masaaki , Tamada Yasushi 
Published: May 2022

AbstractSpider silk has garnered attention as a structural material and a medical resource for next generation because it is tough, lightweight, and biodegradable. Nonwoven silk fabrics are emerging in research and industries owing to advanced electrospinning techniques. Several studies have reported nonwoven fabrics made of spider silk‐like proteins, which are originated from recombinant expression systems, with lower molecular weights than the natural counterpart. The lower molecular weight causes a lack of mechanical strength and durability, preventing the evaluation of industrial potential of the spider silk‐based nonwoven fabric to use as a structural and medical material. In this study, an electrospun nonwoven fabric is produced using native spider silk fibers forcibly reeled from live spiders. The spider silk‐based nonwoven fabrics demonstrate cell compatibility, and the mechanical properties are superior to the silkworm silk‐based nonwoven fabrics. The availability of spider silk‐based nonwoven fabrics introduces an unexplored set of potential uses, along with the context of sustainable development goals.
Modification of reactive PB‐g‐SAG core–shell particles to achieve higher toughening ability for brittle polylactide
Authors: Hao Chunbo , Zheng Shusong , Sun Shulin 
Published: May 2022

AbstractCore–shell structured particles have been used to toughen brittle polylactide (PLA) extensively. In this research, reactive core–shell (RCS) particles with polybutadiene (PB) as core and the terpolymer styrene–acrylonitrile‐glycidyl methacrylate as shell were prepared to improve the toughening ability of RCS for PLA. The tert‐dodecyl mercaptan (TDDM) content was varied during polymerization and higher TDDM concentrations induced lower grafting and cross‐linking of the PB phase, which significantly influenced the dispersed phase morphology and toughness of RCS toughened PLA blends. With the increase of TDDM content, the phase morphology of RCS changed from uniform dispersion, net‐like structure to an agglomeration pattern. The impact strength of PLA blends increased with TDDM content and reached 922 J/m for the PLA/RCS‐T5 (TDDM: 1.18 wt%), which was 30 times higher than pristine PLA and ~3 times than PLA/RCS‐T0 blend. Higher TDDM contents decreased toughening efficiency. Appropriate TDDM contents decreased the glass transition temperature (Tg) and cross‐linking degree of RCS particles which enhanced the cavitation ability of the PB core phase and promoted the shear yielding of PLA matrix. The modification effect of TDDM solves the problem of insufficient toughening ability of core–shell particles. Under the same toughener content, the modified RCS particles make the PLA blend achieve super toughness.
Synthesis, characterization, conductivity, and gas‐sensing performance of copolymer nanocomposites based on copper alumina and poly(aniline‐co‐pyrrole)
Authors: Sankar S. , Ramesan M. T. 
Published: May 2022

AbstractA series of copolymer nanocomposites based on poly(aniline‐co‐pyrrole) (PANI‐co‐PPy) with different contents of copper alumina (Cu‐Al2O3) nanoparticles were synthesized by benign in situ chemical oxidation polymerization. The structural, thermal transition, and morphological interpretations were carried out by Fourier‐transform infrared spectroscopy (FTIR), x‐ray diffraction (XRD), differential scanning calorimetry (DSC), and high‐resolution transmission electron microscope (HR‐TEM). The electrical properties such as alternating current (AC) conductivity and dielectric measurements were performed at room temperature to verify their application in developing new electronic devices. The presence of nanoparticles in the copolymer and the synergistic interaction in the copolymer matrix was confirmed by FTIR and XRD. HR‐TEM indicates the nanosized uniform dispersion of nanofiller in the copolymer matrix. DSC revealed a reduction in the flexibility of polymer with an increase in glass transition temperature of copolymer composites. AC conductivity measurement manifested an increased hopping of charge carriers in nanocomposites when compared with pristine PANI‐co‐PPy. Dielectric properties were maximum for copolymer with 5 wt% Cu‐Al2O3. Excellent gas sensing traits were observed for copolymer nanocomposites due to the electron transfers existing between PANI‐co‐PPy and ammonia gas. The maximum gas‐sensing properties and electrical conductivity were observed for 5 wt% copolymer composites. The magnificent material properties make PANI‐co‐PPy/Cu‐Al2O3 nanocomposites, a promising contender for developing nano‐electronic devices.
The influence of resilience on social creativity: Chain mediation effects of sense of humor and positive mood
Authors: Li Yadan , Liu Chunyu , Yang Yilong , Du Ying , Xie Cong , Xiang Shuoqi , Duan Haijun , Hu Weiping 
Published: May 2022

AbstractThough previous research has established a strong link between resilience and cognitive creativity, few studies have extended this association to social creativity. The underlying mechanisms of the influence of resilience on social creativity remain unknown. Therefore, the current study introduced sense of humor and positive mood to explore the influence of resilience on social creativity. We established a chain mediation model with data from 186 Chinese college students. The results showed that resilience was associated with social creativity. The sense of humor and positive mood were serial mediators in this relationship. The results have demonstrated that student participants with higher levels of resilience are more likely to use humor in their study, which may help them get a more positive mood than their counterparts with lower levels of resilience. Then, positive mood is conducive to students' performance of social creativity.
Prediction of tropical cyclone precipitation over China by the DSAEF_LTP model
Authors: Ding Chenchen , Su Zhizhong , Ren Fumin , Wong Wai‐Kin , Chen Boyu , Ren Hongchang 
Published: May 2022

AbstractThe Dynamical–Statistical–Analog Ensemble Forecast for Landfalling Typhoon Precipitation (DSAEF_LTP) model was used to forecast the accumulated precipitation of 92 tropical cyclone cases from 2004 to 2018 in China. Through the basic experiment of 76 training samples from 2004 to 2016, the best forecasting scheme of the DSAEF_LTP model in China was selected. The forecasting performance of the DSAEF_LTP model in 16 independent samples (2017–2018) with this scheme was found to be comparable to four numerical weather prediction (NWP) models (European Centre for Medium‐Range Weather Forecasts, Global Forecast System, Global/Regional Assimilation and Prediction Enhanced System, and Shanghai Meteorological Service WRF ADAS Real‐Time Modeling System). Specifically, the prediction ability of the DSAEF_LTP model ranked third among the five models. Meanwhile, the prediction performance of the DSAEF_LTP model in different areas demonstrated clear regional characteristics with the single best forecasting scheme for the whole of China, providing a skillful forecast in the coastal areas of southeast and south China. To improve the performance of the DSAEF_LTP model, China was divided into three subregions (south, southeast, and northern China), and subregion experiments were conducted. After regionalization, the forecasting performance of the DSAEF_LTP model improved to some extent. In general, the TSsum (sum of the threat score with precipitation over 250 mm and 100 mm) of the DSAEF_LTP model in the subregion experiments was 0.236, which represented an increase of 19.8% from the value of 0.197 in the basic experiment. Compared with the four NWP models, the TSsum of the DSAEF_LTP model was higher than that of the Global Forecast System (0.225), ranking it second only to the Shanghai Meteorological Service WRF ADAS Real‐Time Modeling System (0.248). In addition, the bias scores of different models showed that the DSAEF_LTP model had a tendency of false alarms, whereas the NWP models tended to misses.
Structural reliability analysis of automotive parts based on strength degradation and abrasion and correlation
Authors: Yang Zhou , Kou Maomao , Rao Singiresu S , Zhang Yimin 
Published: May 2022

AbstractIn this paper, based on Shcaff residual strength theory, the effect of abrasion is considered while the strength degradation of parts is studied. Based on the maximum abrasion, a stress‐strength interference model considering strength degradation and abrasion is established. Then, the reliability and reliability sensitivity of vehicle parts are analyzed by using the first‐order second moment and random perturbation method, and they are verified by the Monte Carlo method. The fitting results are good. It provides a more practical analysis method for engineering analysis. At the same time, based on the correlation between variables, the effect of correlation coefficient on the reliability of vehicle tension rod is discussed. The reliability index and reliability of the correlation coefficient of vehicle tension rod are analyzed, and the reliability sensitivity of the correlation coefficient is also analyzed. At the same time, the gradient reliability of vehicle tension rod geometry is analyzed based on strength degradation theory. Found that if the influence of multiple correlation coefficients on reliability is increased (decreased), then the influence of parameter correlation on reliability will further increase (decrease). On the contrary, if the influence of multiple correlation coefficients on reliability increases and decreases, the reliability change needs to be analyzed specifically. In other words, the influence of multiple correlation coefficients on reliability will produce superposition effect. It provides a new direction for the study of correlation coefficient.
Optimal periodic resource allocation in reactive dynamical systems: Application to microalgal production
Authors: Bernard Olivier , Lu Liu‐Di , Salomon Julien 
Published: May 2022

AbstractIn this article, we focus on a periodic resource allocation problem applied on a dynamical system which comes from a biological system. More precisely, we consider a system with resources and activities, each activity use the allocated resource to evolve up to a given time where a control (represented by a given permutation) will be applied on the system to reallocate the resources. The goal is to find the optimal control strategies which optimize the cost or the benefit of the system. This problem can be illustrated by an industrial biological application, namely, the optimization of a mixing strategy to enhance the growth rate in a microalgal raceway system. A mixing device, such as a paddle wheel, is considered to control the rearrangement of the depth of the algae cultures, hence the light perceived at each lap. We prove that if the dynamics of the system is periodic, then the period corresponds to one reallocation whatever the order of the involved permutation matrix is. A nonlinear optimization problem for one reallocation process is then introduced. Since permutations need to be tested in the general case, it can be numerically solved only for a limited number of . To overcome this difficulty, we introduce a second optimization problem which provides a suboptimal solution of the initial problem, but whose solution can be determined explicitly. A sufficient condition to characterize cases where the two problems have the same solution is given. Some numerical experiments are performed to assess the benefit of optimal strategies in various settings.
Hafnium Oxide (HfO2) – A Multifunctional Oxide: A Review on the Prospect and Challenges of Hafnium Oxide in Resistive Switching and Ferroelectric Memories
Authors: Banerjee Writam , Kashir Alireza , Kamba Stanislav 
Published: May 2022

AbstractHafnium oxide (HfO2) is one of the mature high‐k dielectrics that has been standing strong in the memory arena over the last two decades. Its dielectric properties have been researched rigorously for the development of flash memory devices. In this review, the application of HfO2in two main emerging nonvolatile memory technologies is surveyed, namely resistive random access memory and ferroelectric memory. How the properties of HfO2equip the former to achieve superlative performance with high‐speed reliable switching, excellent endurance, and retention is discussed. The parameters to control HfO2domains are further discussed, which can unleash the ferroelectric properties in memory applications. Finally, the prospect of HfO2materials in emerging applications, such as high‐density memory and neuromorphic devices are examined, and the various challenges of HfO2‐based resistive random access memory and ferroelectric memory devices are addressed with a future outlook.
A phase 1b open‐label study of sodium selenate as a disease‐modifying treatment for possible behavioral variant frontotemporal dementia
Authors: Vivash Lucy , Malpas Charles B. , Meletis Christian , Gollant Meghan , Eratne Dhamidhu , Li Qiao‐Xin , McDonald Stuart , O'Brien William T. , Brodtmann Amy , Darby David , Kyndt Christopher , Walterfang Mark , Hovens Christopher M. , Velakoulis Dennis , O'Brien Terence J. 
Published: May 2022

AbstractIntroductionSodium selenate increases tau dephosphorylation through protein phosphatase 2 activation. Here we report an open‐label Phase 1b study of sodium selenate as a disease‐modifying treatment for behavioral variant frontotemporal dementia (bvFTD).MethodsTwelve participants with bvFTD received sodium selenate (15 mg, three times a day) for 52 weeks. Safety assessments were carried out throughout the trial. Primary outcomes were frequency of adverse events (AEs), serious adverse events (SAEs), and discontinuations. Secondary outcomes of potential efficacy included cognitive and behavioral assessments, magnetic resonance imaging (MRI) whole brain volume, and cerebrospinal fluid (CSF) and blood total tau (t‐tau), phosphorylated tau (p‐tau), and neurofilament light (NfL) levels, which were measured at baseline and at week 52.ResultsSodium selenate was safe and well tolerated. All participants completed the study, and the majority (64.7%) of reported AEs were mild. One SAE occurred, which was not treatment related. Small declines in MRI and cognitive and behavioral measures were observed over the treatment period. There was no evidence for change in CSF protein levels (t‐tau, p‐tau, or NfL). Further analysis showed two distinct groups when measuring disease progression markers over the course of the study—one (n = 4) with substantial brain atrophy (2.5% to 6.5% reduction) and cognitive and behavioral decline over the 12‐month treatment period, and the second group (n = 7) with no detectable change in cognitive and behavioral measures and less brain atrophy (0.3% to 1.7% reduction).ConclusionSodium selenate is safe and well tolerated in patients with bvFTD. Randomized‐controlled trials are warranted to investigate potential efficacy.