bluuebunny/crossref_metadata_2025_split huggingface dataset:
Сluster-oriented interaction of organizations providing paid medical services
Authors: Mashninova Yu. V. 
Published: June 2022

Purpose: preparation of evidence-based proposals for the formation of cluster-oriented interaction of medical organizations providing paid services.Methods: the study is based on the use of a number of universal and special research methods. In particular, the cluster analysis method was used in the search for the most effectively complementary medical organizations of various forms of ownership. Statistical analysis was applied to study their activities in the provision of paid services.Results: the article provides a brief theoretical analysis of the essence of the concept and the basic principles of «cluster-oriented interaction» in relation to Russian organizations of various forms of ownership in the segment of dentistry with a rationale for the relevance of the application in the current socio-economic situation. A model of cluster-oriented interaction has been built and a method for searching for organizations that most effectively complement each other based on multivariate statistical analysis (cluster analysis) has been proposed, which makes it possible to increase the efficiency of their functioning and the quality of medical services provided.Conclusions and Relevance: the developed approaches to the implementation of cluster-oriented interaction of organizations providing paid medical services to the population of childhood allow taking into account the specifics and features of the functioning of healthcare organizations in a critically complex and unstable socio-economic situation in the country. The principles and possibilities of mechanisms for coordinating the joint work of medical healthcare organizations in the direction of obtaining a synergistic effect due to the association of clinics formed on mutually beneficial terms, which increases their competitiveness in the current socio-economic situation, are formulated. The most significant component in the article is the development of methodological approaches to the organization of the joint use of material and technical resources.
Clinical outcomes of S2 Alar-Iliac screw technique in the treatment of severe spinal sagittal imbalance: a retrospective 2-year follow-up study
Authors: Zhao Yao , Shu Jianchuan , Qi Longtao , Yang Chengxian , Xu Beiyu , Yu Zhengrong , Li Chunde 
Published: June 2022

<p class="abstract"><strong>Background: </strong>The treatment of adult spinal deformity (ASD) remains a significant challenge, especially in elderly patients. This study aimed to evaluate the outcomes of the S2AI screw technique in the treatment of severe spinal sagittal imbalance with a minimum 2-year follow-up.</p><p class="abstract"><strong>Methods: </strong>From January 2015 to December 2018, 23 patients with severe degenerative thoracolumbar kyphosis who underwent placement of S2AI screws for long segment fusion were retrospectively reviewed. Patients were divided into group A (no mechanical complications, 13 cases) and group B (with mechanical complications, 10 cases) according to the occurrence of mechanical complications at the last follow-up. Radiographic parameters were compared between groups preoperatively, 1 month postoperatively and at the last follow-up. Risk factors for mechanical complications were analyzed.</p><p class="abstract"><strong>Results:</strong> The incidence of mechanical complications was 43.5% and the revision rate was 17.4%. At 1 month postoperatively, sagittal correction was better in group A than in group B (p&lt;0.05). The area under the curve for predicting mechanical complications of sacral slope (SS), lumbar lordosis (LL), PI (pelvic incidence)-LL at 1 month postoperatively were 0.762 (p=0.035), 0.896 (p=0.001) and 0.754 (p=0.041) respectively and the best cut-off values were 24.1°, 32.8°and 12.0°. The sagittal correction of both groups was partially lost at the last follow-up.</p><p class="abstract"><strong>Conclusions:</strong> A high incidence of mechanical complications was observed in long-segment corrective surgery with the S2AI screw technique for severe spinal sagittal imbalance. Inadequate sagittal correction is a risk factor for the development of mechanical complications.</p><p class="abstract"> </p>
Understanding the pattern and volume of various orthopaedic disorders observed at a tertiary care hospital, before and during the COVID-19 pandemic
Authors: Rathod Girish , Borole Pushkar , Shetty Chandan , Raut Nitin , Britto Namrata , Gawali Vijaykumar 
Published: June 2022

<p><strong>Background:</strong> The COVID-19 pandemic has lead to a huge loss of life and disruption of lifestyle. The pandemic has also led to disruption in the health sector, as significant changes in the pattern of hospital admissions, medical care and variations in disorders have been observed especially in the orthopaedics department. To assess the change in pattern and volume of trauma in our region, we evaluated data from our center for the pandemic period and compared it with the previous years’ data (pre-pandemic period).</p><p><strong>Methods:</strong> Comparison of orthopaedic in-patient records was carried out of the pre-pandemic and during the COVID-19 period, to assess the effect of COVID-19 on the orthopaedic in-patient load and prevailing diseases. Medical records of the patients were analyzed and the data collected were subjected to statistical analysis using IBM SPSS software version 1.0.</p><p><strong>Results:</strong> Significant reduction in patient load was observed during the pandemic period. Cases of various types of fractures were observed to be high in number, followed by arthritis. The only disorder that was observed to be highly prevalent in both the periods is proximal femur fractures.</p><p><strong>Conclusions:</strong> A high variation was observed in both the volume and nature of trauma presentations during the COVID-19 lockdown. A significant decrease in overall admissions was observed, this could be related to the period of societal restrictions and nationwide lockdown.</p><p><strong> </strong></p>
A comparative study of radiofrequency micro-needling with platelet rich plasma and fractional LASER in acne scar management
Authors: Hoq Abu Jafar M. Shahidul , Alam M. Shah , Rahman G. M. Matiur 
Published: June 2022

<p class="abstract"><strong>Background:</strong> Acne scars (AS) results in permanent scarring causes facial disfigurement to the patients. The aim of the study was to assess the comparative effectiveness and outcomes of radiofrequency micro needling and fractional carbon dioxide laser methods in treating acne scars.</p><p class="abstract"><strong>Methods:</strong> This comparative observational study was conducted in the Ibn Sina diagnostic and consultancy center, Dhaka, Bangladesh during the period from January 2019 to December 2020. In total 30 patients with acne scar were selected as the study population. Among total participants, 15 patients who underwent radiofrequency micro needling treatment method were denoted as group-1 and the rest 15 patients who underwent carbon dioxide laser treatment method were denoted as group-2 patients. All data were processed, analyzed and disseminated by Microsoft (MS) office and statistical package for the social sciences (SPSS) version 26.<strong></strong></p><p class="abstract"><strong>Results:</strong> In this study, in group A as per Goodman and Baron scale at the baseline 40% had grade-3 and 60% had grade-4 status. In the same group, after treatment 23.33, 30.00%, 20.00% and 13.33% patients improved up to grade 1, grade 2, grade 3 and grade 4 status respectively. On the other hand, in group-2, after treatment 26.67%, 50.00%, 20.00% and 13.33% patients improved up to grade 1, grade 2, grade 3 and grade 4 status respectively. Finally, according to the mean Goodman and Baron scale scores in both the groups, we found extremely significant correlations between both the baseline and after treatment status where &lt;0001.</p><p><strong>Conclusions:</strong> Both radiofrequency micro needling and fractional CO<sub>2</sub> laser treatment methods are effective for the treatment of acne scars. </p>
Speech Intelligibility Index: A Literature Review
Authors: Taghavi Seyyed Mohanmmad Reza , Mohammadkhani Ghassem , Jalilvand Hamid 
Published: June 2022

Background and Aim: Speech is known as the most important auditory signal that humans deal with it. Noise can mask speech and prevent spoken information from reaching us. Researchers have been trying to develop indexes to assess speech intelligibility. Speech Intelligibility Index (SII) is one of these indicators and we intend to introduce its nature and applications.
Recent Findings: SII is a method that numerically demonstrates the ability to hear speech in difficult listening situations. The number 1.0 indicates that all spoken information is available, while 0.0 indicates that the person does not have access to any information. Hearing loss changes a person’s scores on this index, so we need to use corrective factors to more accurately estimate speech intelligibility. In children, the SII score is different from adults. This indicator can be used in the improvement of hearing aid fitting and more accurate adjustment of cochlear implants. The frequency importance function used to calculate SII has a unique shape in each language. Therefore, SII will also differ in different languages, depending on the nature of each language.
Conclusion: SII has emerged as a practical indicator among objective assessments of speech intelligibility. Many have tried to extend and prepare it for use in different groups. Therefore, care should be taken about the use of this index in hearing-impaired people, children, with hearing aids or cochlear implant patients, etc. Evaluation of this index in other languages can help to better adjust the hearing aid based on the characteristics of each language.

Keywords: Speech intelligibility index; hearing loss; children; hearing aid; cochlear implant; language
Validity and Reliability of theArabicVersion of Children’s Auditory Performance Scale
Authors: Ghuzlan Ghufran , Mohsen Samer Mohamad 
Published: June 2022

Background and Aim: Central auditory processing disorder (CAPD) is seen in a wide array of populations, including children and adults. CAPD is characterized by deficits in one or more auditory abilities, causes difficulties in auditory discrimination, temporal and binaural processing although hearing thresholds are in the normal range. Children’s auditory performance scale (CHAPS) is a screening instrument. This study examined the reliability and validity of the Arabic version of children’s auditory performance scale.
Methods: In this cross-sectional study, 50 healthy children were included. The children’s ages ranged from seven to nine years, and they passed the screening test using distortion product otoacoustic emissions before administering the scale in the translation process, the back- translation method was used, in addition to the face validity procedure. Teachers fulfilled the questionnaire in the presence of an audiologist. After two weeks, the scale was re-administrated, and then the statistical analysis was done to examine the reliability and validity of Arabic version of CHAPS (CHAPS-AR).
Results: The internal consistency was examined with Cronbach’s α (α=0.997), for test- retest reliability, Pearson›s (r) was examined (r=0.994) and when executing the face validity, five experts agreed that the CHAPS-AR has a clear structure, syntax and it is easy to understand and use.
Conclusion: The Arabic version of CHAPS can be considered a reliable and valid screening instrument for clinical and research use

Keywords: Central auditory processing disorder; screening; children; auditory; Arabic; validity
Design, Synthesis and Characterization of Nano niosomal Delivery system Containing paclitaxel drug for Drug Delivery to Osteosarcoma Cell Line (Saos-2)
Authors: Pourmahmoudian Mohammad Javad , Kalantar Seyed Mahdi , Haghiralsadat Bibi Fatemeh 
Published: June 2022

Introduction: Osteosarcoma is the most common type of bone cancer which current chemotherapy treatment strategies have not been very successful due to multiple drug resistance and diverse side effects. The use of nano niosomal delivery system as a drug delivery is one of the new approaches to overcome these limitations. Paclitaxel is an anti-cancer chemotherapy drug used in the treatment of various types of cancers. In this study, various niosomal formulations was designed and synthesized to load Paclitaxel to increase drug efficiency on Saos-2 cell line and overcome the problems of the present treatment..
Methods: Various neosomal formulations containing paclitaxel anti-cancer drug were designed and synthesized. For this purpose, neosomal formulations were prepared based on the ratio of different cholesterol and surfactants. Niosomal formulations and their effects on drug loading and drug release were then studied and interpreted. Cytotoxicity on Saos-2 cell line was assessed using GraphPad Prism 9 MTT test software.
Results: PEGylate's niosomal formulation with cholesterol: Tween 60 and ratio (25:75) has the highest paclitaxel insertion efficiency of 74.89%, size 115.4 nm, surface charge of -12.97 mV and the release 79.83%. This formulation had the highest cumulative release and was considered as a final and optimal was selected. Optimal PEGylate's niosomal system containing paclitaxel was able to show higher toxicity on Saos-2 cell line than free drug. Moreover, this nanosystem alone and without drug had no significant toxicity effect in normal fibroblast cell line (HFF).
Conclusion: The findings of this study indicate that the use of PEGylated niosomal nanocarriers can be used as a promising strategy for future studies in the treatment of bone cancer, especially osteosarcoma.
Prevalence and Risk Factors for Trichomonas vaginalis Infection among Pregnant Women Seeking Primary Health Care in Sana'a City, Yemen
Authors: Al-Mekhlafi Abdulsalam M. , Al-Eryani Samira M. A. 
Published: June 2022

Objective: To determine the prevalence and risk factors for Trichomonas vaginalis infection among pregnant women seeking health care in Sana’a city.
Methods: This cross-sectional study was conducted among pregnant women seeking health care in private clinics and governmental primary health care centers in Sana’a during the period from October 2014 to June 2015. Data on sociodemographic and clinical characteristics as well as possible risk factors of T. vaginalis infection were collected from 287 pregnant women using a pre-designed questionnaire by trained researchers. Vaginal discharges were then collected and examined microscopically for motile T. vaginalis trophozoites.
Results: The overall prevalence of T. vaginalis infection was 11.1%, with a higher infection rate among pregnant women aged 26-40 years old, housewives and rural residents. Age, literacy status and the age at first sexual intercourse were signiﬁcantly associated with T. vaginalis infection among pregnant women. Presence of vaginal discharge (OR = 8.33; 95% CI: 2.47–28.03, P <0.001), itching (OR = 2.57; 95% CI: 1.02–6.48, P = 0.027) and presence of unpleasant odor (OR = 4.37; 95% CI: 1.63–11.70, P = 0.001) were the clinical manifestations significantly associated with T. vaginalis among pregnant women.
Conclusions: T. vaginalis is prevalent among pregnant women seeking health care in Sana’a, particularly housewives, illiterate women and those coming from rural areas. Presence of vaginal discharge with unpleasant odor and itching are associated with a higher risk of infection among symptomatic women. Further large-scale studies are required to determine the prevalence and risk factors among women of the reproductive age in Yemen.
Fracture Strength of Acrylic Resin Reinforced with Glass Fibers in Simulated Implant-Supported Overdenture Abutments
Authors: Moftah Heba M. , Turkmani Ibrahim , Darwich Khaldoun 
Published: June 2022

Objective: To evaluate the effect of glass fibers on acrylic resin fracture strength in simulated implant-supported overdenture (IOD) abutments.
Methods: A model was designed to simulate the clinical situation of an IDO (50 12 1.5 mm). Thirty models were divided into three equal groups: ten models not supported with glass fibers (control group), ten models with one layer of glass fibers (experimental group I) and ten models with two layers of glass fiber (experimental group II). All models were exposed to a three-point bending test, and fracture loads were analyzed using a one-way analysis of variance (ANOVA) followed by Bonferroni post-hoc test.
Results: IOD models reinforced with two layers of glass fibers (experimental group II) showed a mean ultimate load at fracture of 48.69 ± 3.71 Newton (N) compared to mean loads of 32.78 ± 2.41 N and 24.42 ± 2.73 N for the models reinforced with one layer (experimental group I) and non-reinforced with glass fibers (control group), respectively. ANOVA showed a statistically significant difference between the three groups regarding the mean ultimate load at fracture, and Bonferroni post-hoc test showed statistically significant differences between both experimental groups and the control group as well as between experimental group I and experimental group II.
Conclusions: The fracture strength of IDO abutments increases significantly by the addition of acrylic resin pre-impregnated with glass fibers, even when the thickness of acrylic is thin.
Prevalence of Nocturnal Enuresis among Schoolchildren in Sana’a City, Yemen
Authors: Al-Zubairi Lutf M. , Al-Emad Adel A. , Bin Mohanna Mabrook , Al-Bada’ani Tawfik H. 
Published: June 2022

Objective: To estimate the prevalence, frequency and time of nocturnal enuresis (NE) among primary schoolchildren in Sana’a city, Yemen.
Methods: This was a cross-sectional study was conducted among 2689 schoolchildren in the primary schools of four randomly selected districts in Sana’a city in the period from September 2012 to December 2013. Data about sociodemographic characteristics, frequency, time, psycho-social effects and the factors possibly associated with NE among children were collected using a pre-designed questionnaire and analyzed using appropriate statistical tests.
Results: The overall prevalence of NE was 11.2%, which was significantly higher among males than females (13.0% vs. 10.0%, respectively; P = 0.044) and decreased significantly with increasing age (P <0.001). More than half of children (55.3%) in Sana’a city had the habits of drinking excess fluids and tea at night and/or deep sleeping. Of physical and health disorders, difficulty in breathing and urinary tract infections were the two most frequent conditions among children with NE, being observed among 29.6% and 23.9% of cases, respectively. However, urogenital anomalies and mental retardation were the least frequent conditions in children with NE, being observed among 5.8% and 1.3% of cases, respectively. On the other hand, marital problems (24.8%) and arrival of a new baby (17.9%) were the most frequently observed social conditions among children with NE, while death in the family (8.5%) and parental separation (6.0%) were the least frequently observed conditions.
Conclusions: NE is prevalent among 11.2% of schoolchildren in Sana’a city with a significantly higher, though slight, rate among males. This rate is lower than the rates reported from Aden and Mukalla cities in the country and from Saudi Arabia and Turkey. However, it is higher than those reported from Iran and Malaysia. About a third of children experience nightly NE, whereas the lowest proportion of children experience NE twice a month. The habits of drinking excess fluid and tea at night and/or deep sleeping, the disorders of difficulty in breathing and urinary tract infections and the social conditions of marital problems and arrival of a new baby are the most frequent observations among children with NE in Sana’a city.
Carryover effects of crop thinning and foliar N fertilisation on grape amino N composition
Authors: Verdenal Thibaut , Dienes-Nagy Ágnes , Zufferey Vivian , Spring Jean-Laurent , Spangenberg Jorge E. , Viret Olivier , Van Leeuwen Cornelis 
Published: June 2022

Nitrogen (N) is an essential element for vine development and yield; it is also involved in the winemaking process and significantly affects wine composition. It is therefore essential to control and optimise plant N use to ensure an adequate N composition of the grapes at harvest. An improved understanding of the impact of cultivation practices on plant N metabolism would allow a better orientation of technical choices with the objective of quality and sustainability (i.e., fewer inputs, more efficiency).Our trial focused on the impacts of fertilisation and crop thinning on grape N composition. A wide crop load gradient was set up in a homogeneous plot of Chasselas (Vitis vinifera L.) in an experimental vineyard in Switzerland. Foliar urea was applied at veraison in order to compare it with an unfertilised control. Vine development and grape composition were evaluated over two years, with particular attention to the carryover effects of both fertilisation and crop thinning.Foliar N fertilisation effectively increased the amount of N in grapes at harvest in the same year, but had no impact on grape ripeness or carryover effect on year n + 1. Conversely, crop thinning improved grape maturity by reducing fruit N and C demand. Interestingly, amino N proportions could be distinguished according to crop load, while the global grape N concentration at harvest remained unchanged. Some amino acids were more affected by crop thinning than others. The concentrations of alanine, γ-aminobutyric acid (GABA), serine and threonine were reduced by crop thinning. Crop thinning had a strong carryover effect on year n + 1. The carryover impact of crop thinning on grapes in terms of both maturation index and N composition could be observed at the onset of grape ripening on year n + 1.This experiment highlighted the influence of the previous year’s agricultural practices on grape C and N accumulation before and during the ripening phase. Consequently, the modulation of grape composition at harvest should be considered over two consecutive years. These results will contribute to the improvement of predictive models and sustainable agronomic practices in perennial crops.
PENGARUH PENGGUNAAN ABU DAUN BAMBU SEBAGAI PENGGANTI SEBAGIAN SEMEN TERHADAP KUAT TEKAN BETON SEBAGAI PENDUKUNG BAHAN AJAR MATA KULIAH TEKNOLOGI BETON
Authors: Aji Firmansyah  , Anisah  , Santoso Sri Handoyo  
Published: June 2022

The purpose of this study was to determine the compressive strength of concrete using bamboo leaf ash as a partial replacement of cement with a target compressive strength of 25 MPa at the age of 28 days with the use of water cement factor (FAS) 0,5 and variation percentage levels of bamboo leaf ash that be used are 0%, 5%, 7%, 9%, and 11% of the total weight of cement. The The amboo leaf ash used comes from Andong bamboo species. In this study use the experimental method with cylindrical specimens with a diameter of 15 cm and a height of 30 cm as many as 3 samples in each percentage level of bamboo leaf ash. Concrete mix design refers to SNI 03-2834-2000. The results obtained indicate that bamboo leaf ash can increase the compressive strength of concrete when compared to the control concrete in this study even though the increase is not too large. The compressive strength of concrete at the age of 28 days at 0%, 5%, 7%, 9%, and 11% percentages levels of bamboo leaf ash were 16,448 MPa ; 18,768 MPa ; 18,297 MPa ; 14,958 MPa ; dan 12,827 MPa.