bluuebunny/crossref_metadata_2025_split huggingface dataset:
Police resource distribution in China: spatial decision making based on PGIS-MCDA method
Authors: Zhang Ning , Haoran Xu , Jiang Feng , Wang Dawei , Chen Peng , Zhang Qing 
Published: July 2022

PurposeBased on the theoretical viewpoints of criminal geography and environmental criminology, this research uses spatial multi-criteria decision-making methods. In the process of spatial decision-making and optimization of police resources, researchers fully consider the dynamic application of Geographic Information System (GIS) and the effects of spatial prevention and control.Design/methodology/approachResearchers use an integrated method combining Policing Geographic Information System (PGIS) and multi-criteria decision analysis (MCDA). On the one hand, police GIS has an excellent visual data analysis platform and integrated decision support system in data management, spatial analysis, data exploration and regression analysis. On the other hand, through the design of the indicator system, the quantification of indicators, the determination of weights, comprehensive evaluation and sensitivity analysis, MCDA can select the best plan from a large number of alternatives. When joining MCDA, the spatial dimension will bring the research results closer to the real world.FindingsThe study finds that the crime of burglary is affected to a certain extent by the distribution of police forces, the location of police units. Another important finding of this research is the correlation between more precise preventive measures and the crime of burglary.Originality/valueFrom a practical point of view, this research would help advance the role of police units and law enforcement agencies in preventing burglary crimes and provide experience for the allocation of regional police resources.
Intersections of women’s identities in professional accountancy careers
Authors: Tiron-Tudor Adriana , Faragalla Widad Atena 
Published: July 2022

PurposeThis study aims to explore intersectional gender inequalities that exist in accounting organizations.Design/methodology/approachA review of the literature, covering the period from 1990 to 2020, assesses the intersectionality of professional and social factors that shape inequalities in women’s professional accounting careers.FindingsThis study presents the complex facets of women’s inequality in gendered accounting organizations. The results reveal that inequity persists in accounting organizations despite organizational changes. The findings highlight the relevance of further research in gendered organizations to capture the intersectionality of gender with other forms of inequality.Practical implicationsThis review informs professional organizations, accountants and company managers about the persistence of gender concerns in the accountancy profession in the last 30 years, despite stated accounting profession commitments to achieve gender equality, as promoted by United Nations Sustainable Development Goals. Moreover, some possible solutions are proposed.Originality/valueThis study focuses on a complex and challenging issue, contributing to the literature by extending classical narrative literature. This study presents a structured view of the various intersections of professional and social characteristics that created inequalities and the suggested solutions.
Social capital in urban agriculture initiatives
Authors: Caldas Luíza Costa , Christopoulos Tania Pereira 
Published: July 2022

PurposeThe study aims to investigate urban agriculture in the city of São Paulo from the perspective of social capital. The specific objectives are (1) to identify the effects of social capital on urban agriculture and (2) to investigate social capital formation (its sources and challenges imposed onto its development).Design/methodology/approachInitially, a review of the literature was carried out in order to understand the main concepts used in the field of study. Semi-structured interviews were also carried out with people from urban agriculture initiatives, and they were analyzed under the lens of social capital.FindingsAspects of social capital were recognized and organized in a framework including sources, effects and challenges. The first deals with consummatory or instrumental sources that generate social capital. The second deals with the following effects: generation of human capital, citizenship, engagement, access and mobilization of resources, and access to information. The third deals with the challenges to its formation related to homophily and the perception of benefits from this form of capital.Originality/valueUrban agriculture plays an increasingly important role in relieving the pressure generated by the food production system, being part of the solution to food security and sustainability issues. Many researchers recognize important social aspects acting on the dynamics of the movement and the effects of activities on the generation of social capital. The contribution of this work is to deepen the understanding of this type of capital in the context of urban agriculture.
Errors in positioning of borehole measurements and how they influence seismic inversion
Authors: Fernandes Iris , Mosegaard Klaus 
Published: July 2022

AbstractInversion of seismic data using information from horizontal wells is often hampered by cumulative well‐location errors. These errors can have a significant influence on the final subsurface model derived from the data. To achieve a proper data integration and arrive at correct uncertainty estimates, we formulate the problem in a fully probabilistic framework and present a numerical approach for improving subsurface imaging using uncertain well‐log data and their uncertain locations as well as uncertain seismic data. The result is improved model error quantification in the seismic inversion process.
Voting into a Void? The 2022 Northern Ireland Assembly Election
Authors: Tonge Jon 
Published: July 2022

AbstractThe election to the Northern Ireland Assembly in May 2022 witnessed significant changes to the region's political balance. For the first time, a nationalist party became the largest, with Sinn Féin's new leading position allowing the party to provide the First Minister. The main party of unionism, the Democratic Unionist Party (DUP) was relegated to second place. This runner‐up position entitled the party to nominate the Deputy First Minister. However, in the immediate aftermath of the election, the DUP declined to do so, amid a crisis for the political institutions established under the 1998 Good Friday Agreement. According to the DUP, it would return to power sharing with nationalists only upon removal of the European Union Protocol, agreed between the EU and UK government in 2019. The Protocol uniquely aligns Northern Ireland with EU rules and requires checks on goods travelling between Great Britain and Northern Ireland. Alongside unionist versus nationalist rivalries, however, the election was also marked by the best‐ever performance by a party of the centre ground subscribing to neither ideology, as Alliance more than doubled its Assembly seat tally. It was now possible to speak of three big pillars in Northern Irish politics: unionist, nationalist and non‐aligned, each dominated by a single party. This article examines what happened at the election, assessing the key issues and party fortunes.
Implementation of WeChat‐based patient–doctor interaction in the management of Helicobacter pylori infection: A propensity score matching analysis
Authors: Lin Bo Shen , Li Yue Yue , Qiao Chen , Liu Jing , Wang Juan , Wan Meng , Lin Min Juan , Zhang Wen Lin , Ding Yu Ming , Kong Qing Zhou , Duan Miao , Zuo Xiu Li , Li Yan Qing 
Published: July 2022

ObjectiveWe aimed to investigate if the WeChat‐based patient–doctor interaction could affect treatment outcomes of Helicobacter pylori (H. pylori) eradication compared with conventional patient education (CPE) alone.MethodsPatients treated for H. pylori infection for the first time at our clinic from 1 July 2019 to 31 July 2021 were retrospectively included and divided into the CPE and WeChat groups. Both groups received CPE including verbal education and a specifically designed printout with detailed instructions. Those in the WeChat group were required to join a physician‐managed WeChat group chat and they were encouraged to ask questions for clarification. Baseline characteristics were matched using propensity score matching between the two groups. Relevant knowledge and instructions were occasionally shared. Eradication rate, compliance, and adverse events in the two groups were evaluated.ResultsA total of 348 patients were included after propensity score matching. Intention‐to‐treat analysis revealed eradication rate of 85.6% in the WeChat group and 80.5% in the CPE group (P = 0.199), whereas the per‐protocol eradication rate was 91.1% and 88.2% (P = 0.399), respectively. Compliance did not differ between the two groups (WeChat group vs CPE group: 92.5% vs 91.4%, P = 0.693). The incidences of adverse events were also comparable between the two groups.ConclusionsCPE utilization already yields fair H. pylori eradication rate; however, the WeChat‐based patient–doctor interaction did not yield better results. More appropriate managements are needed in the future to explore the impact of the WeChat platform on H. pylori eradication.
Structural and functional role of Domain I for the insecticidal activity of the Vip3Aa protein from Bacillus thuringiensis
Authors: Lázaro‐Berenguer Maria , Paredes‐Martínez Francisco , Bel Yolanda , Núñez‐Ramírez Rafael , Arias‐Palomo Ernesto , Casino Patricia , Ferré Juan 
Published: July 2022

AbstractVip3 proteins are produced by Bacillus thuringiensis and are toxic against lepidopterans, reason why the vip3Aa gene has been introduced into cotton and corn to control agricultural pests. Recently, the structure of Vip3 proteins has been determined and consists of a tetramer where each monomer is composed of five structural domains. The transition from protoxin to the trypsin‐activated form involves a major conformational change of the N‐terminal Domain I, which is remodelled into a tetrameric coiled‐coil structure that is thought to insert into the apical membrane of the midgut cells. To better understand the relevance of this major change in Domain I for the insecticidal activity, we have generated several mutants aimed to alter the activity and remodelling capacity of this central region to understand its function. These mutants have been characterized by proteolytic processing, negative staining electron microscopy, and toxicity bioassays against Spodoptera exigua. The results show the crucial role of helix α1 for the insecticidal activity and in restraining the Domain I in the protoxin conformation, the importance of the remodelling of helices α2 and α3, the proteolytic processing that takes place between Domains I and II, and the role of the C‐t Domains IV and V to sustain the conformational change necessary for toxicity.
Comprehensive analysis of the expression and prognosis for RBR E3 ubiquitin ligases in lung adenocarcinoma
Authors: Ding Hao , Wang Yuxin , Cui Yuan , Chen Zhike , Li Yu , Yang Jian , Yang Yang , Chen Tengfei , Xia Dian , Li Chang , Xu Chun , Ding Cheng , Zhao Jun 
Published: July 2022

AbstractBackgroundLung adenocarcinoma (LUAD) is the most common subtype of non‐small cell lung cancer and has a poor prognosis. RBR E3 ubiquitin ligases are a special class of E3 ubiquitin ligases which contain three zinc‐bing domains that catalyze ubiquitin to substrate proteins. The RBR family of E3 ubiquitin ligases has been reported in various human malignancies, but the roles of RBR E3 ubiquitin ligases in LUAD remain unclear.MethodsBy using TCGA and Kaplan–Meier plotter databases, we examined the expression and prognostic value of RBR E3 ubiquitin ligases. cBioPortal was used to analyze genetic mutations. The STRING database was used to build a protein interactive network. GO, KEGG, and GSEA were performed to investigate the potential biological functions of RBR E3 ubiquitin ligases.ResultsThe expression of ARIH2, RNF144B, RNF216, and RNF217 was significantly related to the clinicopathological parameters and prognosis in LUAD patients. GSEA enrichment result showed ARIH2, RNF144B, RNF216, and RNF217 were all associated with NADH dehydrogenase complex assembly. GO functional enrichment analysis revealed that four RBR E3 ubiquitin ligases and their interactors were most correlated with ubiquitin‐protein transferase activity. KEGG pathway analysis indicated they were associated with cytosolic DNA‐sensing pathway, RIG‐I‐like receptor signaling pathway and NF‐kappa B signaling pathway.ConclusionsOur comprehensive bioinformatic analysis revealed that ARIH2, RNF144B, RNF216, and RNF217 may be new prognostic biomarkers and these findings will help to better understand the distinct roles of RBR E3 ubiquitin ligases in LUAD.
Nursing outcomes for patients with multiple traumas and impaired physical mobility: An integrative review
Authors: Ferreira Ráisa Camilo , Moorhead Sue Ann , Zuchatti Bruna Valentina , Begnami Natanaellin Eydiane da Silva , Ribeiro Elaine , Carvalho Luciana Aparecida Costa , Duran Erika Christiane Marocco 
Published: July 2022

AbstractPurposeThis research identifies nursing outcomes for patients with multiple traumas who present changes in physical mobility.MethodsThis was a thorough literature review, following Whittemore and Knafl's method and the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses´ guidelines (2005) and adopting the Oxford Center for Evidence‐Based Classification Medicine–Levels of Evidence (2011). The literature search included databases from Virtual Health Library, Cochrane Library, Excerpta Medica Database, Medical Literature Analysis and Retrieval System Online, PubMed, SciVerse Scopus, The Cumulative Index to Nursing and Allied Health Literature, and Web of Science. It was conducted between October and December 2019 and updated in April 2022.FindingsUpon our first analysis of the 254 articles that could correlate to the present study, we concluded that 15 of them are of foremost relevance. The nursing outcomes found are correlated with skin care, position in hospital bed, pressure injury prevention, self‐care assistance to bath, intimate, and oral hygiene, pain control, circulatory precaution, and impaired physical mobility assistance. All of these outcomes are directly or indirectly involved with the consequences of mobility impairment.ConclusionsThe main nursing outcomes of our research identified for patients with multiple traumas were related to mobility, the consequences of immobility, self‐care, and skin maintenance. In conclusion, this review highlights the importance of measuring outcomes related to the provision of nursing care.Implications for Nursing PracticeThe nursing outcomes classification provides results that can be used across the continuum of care to assess the patient's status after nursing interventions. It also allows for improved care for multiple trauma patients who have altered mobility, identifying the real needs of these patients.
Vitamin D supplementation worsens Alzheimer's progression: Animal model and human cohort studies
Authors: Lai Rai‐Hua , Hsu Chih‐Cheng , Yu Ben‐Hui , Lo Yu‐Ru , Hsu Yueh‐Ying , Chen Mei‐Hsin , Juang Jyh‐Lyh 
Published: July 2022

AbstractVitamin D deficiency has been epidemiologically linked to Alzheimer's disease (AD) and other dementias, but no interventional studies have proved causality. Our previous work revealed that the genomic vitamin D receptor (VDR) is already converted into a non‐genomic signaling pathway by forming a complex with p53 in the AD brain. Here, we extend our previous work to assess whether it is beneficial to supplement AD mice and humans with vitamin D. Intriguingly, we first observed that APP/PS1 mice fed a vitamin D‐sufficient diet showed significantly lower levels of serum vitamin D, suggesting its deficiency may be a consequence not a cause of AD. Moreover, supplementation of vitamin D led to increased Aβ deposition and exacerbated AD. Mechanistically, vitamin D supplementation did not rescue the genomic VDR/RXR complex but instead enhanced the non‐genomic VDR/p53 complex in AD brains. Consistently, our population‐based longitudinal study also showed that dementia‐free older adults (n = 14,648) taking vitamin D3 supplements for over 146 days/year were 1.8 times more likely to develop dementia than those not taking the supplements. Among those with pre‐existing dementia (n = 980), those taking vitamin D3 supplements for over 146 days/year had 2.17 times the risk of mortality than those not taking the supplements. Collectively, these animal model and human cohort studies caution against prolonged use of vitamin D by AD patients.
Clinical outcomes and prognostic factors of cone‐beam CT‐guided radiofrequency ablation for pulmonary metastases in colorectal cancer patients
Authors: Hong Hyun Pyo , Kim Hyung Ook , Koo Dong‐Hoe , Lee Yun‐Gyoo , Kim Myung Sub , Ham Soo Youn , Kang Du‐Young , Oh Tae Yun , Lee Hyebin , Jung Kyung Uk , Kim Hungdai 
Published: July 2022

AbstractAimRadiofrequency ablation (RFA) has been increasingly used for the treatment of pulmonary metastases in various malignancies.MethodsA retrospective analysis was performed to establish the safety and efficacy of cone‐beam computed tomography (CBCT)‐guided RFA in patients with metastatic colorectal cancer between 2016 and 2019, and the prognostic factors of local tumor control were assessed.ResultsA total of 31 patients with colorectal cancer underwent 48 sessions of lung RFA. The mean diameter of metastases targeted for RFA was 11 mm (range: 4–32), and the RFA was technically successful in 43 sessions (90%). There were 14 complications (29%), the majority of which required no intervention, with no cases of mortality. The median follow‐up duration from RFA in the surviving 29 patients was 18.0 months. Only two patients (6%) died of disease progression, and the 3‐year overall survival rate was 91% (95% CI: 83–99). Local tumor progression (LTP) of the RFA site was observed in 27%, and the LTP‐free survival rates at 1 and 2 years were 81% (95% CI: 70–82) and 64% (95% CI: 50–77), respectively. Multivariate analysis showed that the progression of extra‐RFA sites and the presence of extrapulmonary metastasis were independent prognostic factors significantly associated with LTP at RFA site.ConclusionLung RFA using CBCT guidance is a comparatively safe and effective option for the treatment of lung metastases from colorectal cancer. However, the control of extrapulmonary metastases should be accompanied by combined or sequential systemic treatment and local treatment.
Physiotherapy students' empathy towards Australians living in rural settings: A pre‐test post‐test evaluation of a stand‐alone rural simulation activity
Authors: Martin Romany , Mandrusiak Allison , Russell Trevor , Forbes Roma 
Published: July 2022

AbstractObjectiveTo investigate how a rural simulation activity influenced physiotherapy students' rural empathy, and to explore students' perception of the activity.SettingA metropolitan university in Queensland, Australia.ParticipantsSecond year undergraduate physiotherapy students.DesignA single cohort pre‐test post‐test evaluation was undertaken to evaluate a rural simulation activity. Participants received the rural simulation activity, featuring an immersive video and telehealth simulation with a standardised patient portrayed by an actor. Participants undertook a structured debrief and guided reflection following the simulation. Outcome measures included the Rural Comprehensive State Empathy Scale (R‐CSES) and the Satisfaction with Simulation Experience Scale. Group interviews were undertaken regarding participant perceptions of the activity. Wilcoxon Rank‐Sum tests were used to analyse survey data, and group interview data were subject to thematic analyses.ResultsA total of 102 students undertook the activity, with an outcome measure response rate of 92.2% (94/102). Intra‐personal rural empathy increased following the activity as demonstrated by the overall R‐CSES score [pre‐test: 101.5 (90–110.75) vs post‐test 107 (100–120); p = <0.001; r = 0.39]. There was high satisfaction with the experience [mean SSES score = 18/21]. Two themes were generated from the group interview data: (1) effect on perceptions of rural practice and (2) feedback regarding the simulation.ConclusionA rural simulation activity using an immersive video, standardised patient, and a structured debrief increased physiotherapy students' empathy towards Australians living in rural settings. Students were satisfied with the activity and felt that it improved their understanding of the challenges of rural healthcare.
Long‐term surgical outcomes of nerve‐sparing discoid and segmental resection for deep endometriosis
Authors: Darici Ezgi , Denkmayr Denise , Pashkunova Daria , Dauser Bernhard , Birsan Tudor , Hudelist Gernot 
Published: July 2022

AbstractIntroductionThe aim of this study was to investigate long‐term outcomes in terms of pain, quality of life (QoL), and gastrointestinal symptoms in women following colorectal surgery for deep endometriosis.Material and methodsIn this historical cohort, women who underwent surgical treatment for deep endometriosis by either nerve‐sparing full‐thickness discoid resection (DR) or colorectal segmental resection (SR) between March 2011 and August 2016 were re‐evaluated through telephone interviews about their long‐term pain symptoms, subjective overall QoL as rated using a score from 0 (worst) to 10 (optimal), and gastrointestinal outcomes reflected by lower anterior resection syndrome (LARS) following a first postsurgical evaluation (visit 1) published previously and a long‐term follow‐up evaluation (visit 2).ResultsThe median long‐term follow‐up time was 35.4 months at visit 1 and 86 months at visit 2. Of 134 patients, 77 were eligible for final analysis and 57 were lost to follow‐up. Compared with presurgical values, QoL scores were significantly increased at both postsurgical evaluation visits in both the SR cohort (scores of 3, 8.5, and 10 at the presurgical visit, visit 1, and visit 2, respectively; p < 0.001) and the DR cohort (scores of 3, 9, and 10, respectively; p < 0.001). Pain scores for dysmenorrhea (SR group scores of 8, 2, and 2, respectively; p < 0.001; DR group scores of 9, 2, and 1, respectively; p < 0.001), dyspareunia (SR group scores of 4, 0, and 0, respectively; p < 0.001; DR group scores of 5, 0, and 1, respectively; p = 0.003), and dyschezia (SR group scores of 8, 2, and 2, respectively; p < 0.001; DR group scores of 9, 2, and 1, respectively; p < 0.001) significantly decreased after surgery and remained stable in both cohorts over the follow‐up period. Minor and major LARS, reflecting gastrointestinal function, was observed in 6.5% and 8.1% of the SR group and in 13.3% and 6.7% of the DR group, respectively, at visit 1 and in 3.2% and 3.2% of the SR group and 0% and 0% of the DR group, respectively, at visit 2, without significant differences between the SR and DR groups.ConclusionsColorectal surgery for deep endometriosis, either by DR or SR, provides stable and long‐term pain relief with low rates of permanent gastrointestinal function impairment.