bluuebunny/crossref_metadata_2025_split huggingface dataset:
Detection of anti-testicular antibodies among infertile males using indirect immunofluorescent technique
Authors: Hazim Hamoode Rana , A. Alkubaisy Sami , A. Sattar Dalal , S. Hamzah Sawsan , Hadi Saleh Tahreer , Laftaah Al-Rubaii Bahaa Abdullah 
Published: November 2022

Introduction and Aim: The antinuclear antibodies (ANA) are unwanted molecules which bind and destroy certain structures within the nucleus. Immunofluorescence is a powerful technique that utilizes fluorescent-labeled antibodies to detect specific target antigens. The aim of this study was to detect the anti-testicular antibody among infertile males in Baghdad city and determine the most common type of infertility.

Materials and Methods: The study involved 73 male (53 infertile and 20 non-infertile) volunteers, at Kamal Al-Samarrai Teaching Hospital in Baghdad, Iraq. Serum collected from the study subjects was tested for steroid-cell antibodies (STC-Ab), anti-nuclear antibody (ANA) and anti-testicular antibodies (ATCA) by Indirect Immunofluorescence assay (IIFA). Data obtained was subjected to statistical analysis using the SPSS program.

Results: In the current study 52.9% of infertile men tested positive for testicular antibodies compared to the control group. The highest rate of testicular cell antibodies was observed in the serum of infertile patients aged between 30-39 years and the lowest in patients aged 50-59 years. The marriage duration among those showing the highest percentage of antibodies against testicular cells was 1-10 years. Study for the association of male infertility type to those positive for ATCA showed almost all (85.7%) patients with necrozoospermia to be positive for ATCA. This was followed by males with azoospermia (50%) and oligospermia (46.9%). The patients were negative for Addison’s disease while a few (28.6%) were positive for lupus erythematosus.
Antibacterial activity of klebocin against methicillin resistance Staphylococcus aureus
Authors: Razooqi Hussein Alyaa , Zamel Khalaf Zainab 
Published: November 2022

Introduction and Aim: Bacteriocins are antimicrobial peptides that have bactericidal and/or bacteriostatic activity against other bacteria. The aim of this study was to assess the antibacterial efficiency of Klebocin a K. pneumoniae bacteriocin, against biofilm formation by clinical isolates of methicillin resistant Staphylococcus aureus MRSA.

Materials and Methods: S. aureus isolated from clinical samples was identified according to vitek 2 system Antibiotic susceptibility test was performed according to disc diffusion method. Vitek 2 compact system was also used to detect MRSA strains. Agar well diffusion method was used to evaluate the antibacterial activity of klebocin from K. pneumoniae towards 11 strains of S. aureus by the microtiter plate method throughout the initial and final steps of biofilm development.

Results: Our finding shown that crude extract of klebocin was active against all the tested pre-formed biofilm of S.aureus isolates and the percentage of inhibition ranging from 78.9-88.5%. Also the results of the current study demonstrated that all matured bacterial biofilm was inhibited in at a percentage ranging from 41.2% - 91.2%.

Conclusion: This finding proved that klebocin had antibacterial activity against planktonic cells of S.aureus in addition to antibiofilm activity against premature and mature biofilm of MRSA. Also klebocin had broad spectrum activity effecting Gram +ve bacteria and its biofilm production.
A study on topography of tibial plateau and its applications in knee arthroplasty
Authors: N. Hema , Mittal Anjana , G. Kamath Venkatesh 
Published: November 2022

Introduction and Aim: This investigation was designed for evaluating the tibial plateau in Indian population and compares the data with other populations. The major intention is to observe if significant difference exists in diverse a demographic profile that necessitates production of population specific implants ensuring success in total knee arthroplasty.

Materials and Methods: Morphometry of 200 adult human tibial plateaus were measured in dry bones using a sliding digital caliper and data analysis was done.

Results: The mean anteroposterior dimension of the medial condyle was 38.98 ± 4.46 mm on the left and 38.81 ± 5.05 mm on the right and the lateral condyle was 32.99 ± 4.01mm on the left and 32.42 ± 4.88 mm on the right. The mean transverse dimension of the medial condyle was 24.95 ± 3.22 mm on the left and 24.54 ± 2.69 mm on the right and the lateral condyle was 28.15 ± 4.10 mm on the left and 27.76 ± 3.50 mm on the right. The anteroposterior dimension of the intercondylar area was 44.78 ± 3.87 mm on the left and 44.19 ± 4.51mm on the right.

Conclusion: The data obtained will help in designing tibial prosthetic implants best suited for Indian population. The surgeon can assess how much a given deformity deviates from the normal values. The dimensions of the tibial plateau vary in different populations and most available prosthesis is designed based on Caucasian data. The tibial prosthetic sizing needs to be population specific to avoid a mismatch or mediolateral overhang.
Expression of autophagy and apoptosis biomarkers in patients with acute ischemic stroke
Authors: Mamytov Mitalip , Mamytova Elmira , Toktomametova Anara , Miklukhin Danil , Yethindra Vityala , Tagaev Tugolbai , Kalikiri Sandhya , Kanteti Krishna Priya 
Published: November 2022

Introduction and Aim: Apoptosis, autophagy, and necrosis are the main mechanisms of neuron death in acute ischemic stroke (AIS). This study aimed to evaluate the expression of apoptosis and autophagy biomarkers in peripheral blood of patients with AIS.

Materials and Methods: Sixty-eight patients (32 men and 36 women) aged 30-60 years with AIS underwent a clinical and neurological examination on the 1st, 7th, and 14th days after the disease onset. The expression of apoptosis and autophagy biomarkers in peripheral blood was evaluated by flow cytometry and compared with the severity of neurological deficit and injury on the 1st, 7th, and 14th days, using correlation analysis.

Results: There is a statistical significance compared with the control group and an increase in the expression of key biomarkers of apoptosis and autophagy was revealed. Increased expression levels of annexin A5 and caspase-3 positively correlate with the severity of neurological deficit and injury on the 1st and 7th days from the onset of the disease.

Conclusion: A direct correlation was revealed between elevated levels of apoptosis and autophagy biomarkers in peripheral blood and severity of neurological deficit and injury on the 1st, 7th, and 14th days from the onset of AIS.
Assessing the potential correlation of polymorphisms in the TMPRSS2 gene with severity of COVID 19 patients
Authors: Zaki Mahdi Nazar , A. M. Khudhair , Sahib Khalil Nawar 
Published: November 2022

Introduction and Aim: Coronavirus disease (COVID-19) is an infectious disease caused by the SARS-CoV-2 virus. Once infected this virus induces several clinical disorders in humans. SARSCoV-2 enters cells via TMPRSS2. Genetic variation in TMPRSS2 could affect the severity of infection. The purpose of this study was to investigate how the (TMPRSS2) gene polymorphism affected COVID-19 severity in patients as well as the effect of age and comorbidities on infection.

Materials and Methods: This cross-sectional analytical study comprised of 400 (185 male, 215 female) Covid-19-infected patients between ages 18-65 receiving treatment in hospitals at Baghdad, Iraq. The patients were divided into three groups: mild, moderate, and severe based on the severity of Covid-19 infection. Baseline data was collected for each patient through interview and questionnaire. Blood collected from patients was subjected to DNA extraction and detecting polymorphisms within SNPs of the TMPRSS2 gene.

Results: The present investigation indicated higher age to be significantly associated with severe COVID-19 infection when compared to moderate and mild infection (36.14 ± 12.716 vs. 48.52 ± 17.513 vs. 59.26 ± 16.035) (F= 3.697, df: 64, P= 0.000). Patients with comorbidities was associated with a greater rate of severe Covid-19 infection (74.2% vs. 25.8%). However, individuals without comorbidities had a considerably lower rate of mild and moderate Covid-19 infection (13.9% vs. 86.1%) and (36% vs. 64%), respectively (x^2: 97.930, df: 2, P = 0.000). SNPs; (rs383510, rs12329760) within the transmembrane TMPRSS2–7113 was studied and we found no significant (P> 0.05) association for these SNPs to severity of Covid-19 infection.

Conclusion: The results show that the allelic variation within the TMPRSS2 (SNP rs2070788) gene to be linked to increasing illness severity in COVID-19 patients.
EKSTRAKSI UNSUR FERRUM DARI LIMBAH PADAT PABRIK PULP DAN KERTAS
Authors: Sembiring Maria Peratenta , Heltina Desi , Chairul Chairul , Zulfansyah Zulfansyah 
Published: November 2022

Functioning industrial waste as raw material or as a product is an achievement that will continue to be optimized, especially in industries where the amount of waste is significant. Pulp and paper mills produce waste in the form of solid, sludge, liquid and gas. The objective of this research is to extract the element ferrum contained in one of the solid wastes in pulp and paper mills. By using two fatty amine extractor, lauryl amine and stearyl amine with ethanol and n-hexane as solvents. The results showed that the use of stearyl amine as an extractor and n-hexane as a solvent with operating conditions of 4 hours and a dose of 5 grams gave the best results with an extraction yield of 10,964 mg/kg.
Primal Images of a Peaceful Being: Tracing a Novel (Works by Alfonsas Nyka-Niliūnas and Adalbert Stifter)
Authors: Tūtlytė Rita 
Published: November 2022

The aim of the article is to examine the longing for a “peaceful being” identified in the works of the 20th-century Lithuanian writer Alfonsas Nyka-Niliūnas and to explore his literary sources. The focus is on the novel Der Nachsommer (1857) [Indian Summer] of the 19th-century Austrian writer Adalbert Stifter, which Nyka-Niliūnas constantly mentions in his diaries. The author of the article also introduces the most important observations by the German / Austrian literary critics about the novel on this subject. From a comparative point of view, the author elaborates on the aspects that are close to the worldview of both Stifter and Niliūnas. Finally, she talks about the history of reception of Stifter’s works mentioned in Niliūnas’s diaries.Stifter’s novel depicts a closed, calm, and „storm-free“ world deliberately created by an individual. In this respect, Niliūnas’s works depict a clear connection between the space of the childhood home and loved ones, providing a sense of security and the importance of consistency and daily monotony that ensures a sense of stability. The relationship with the reality of things in the writers’ works differs: Stifter experiences the positivist closeness to reality, whereas Niliūnas’s works are characterized by the sensory and ontological being.In terms of time, Niliūnas puts his own twist on a safe nest of existence. He perceives the change of the seasons and their turnover as a measure of the stability of existence. The poet stops / restores the flow of time by remembering and by layering the segments of time. In this way, the time revolving around the circle of nature, or the circle of memories ensures the sustainability of the personal world. Stifter’s “Rosenhaus” is an idyllic place where a person goes through a thorough process of self-education (the novel is considered a Bildungsroman).Niliūnas recognizes in Stifter’s novel the importance of selfdevelopment. In silent solitude, to set off purposefully to the worlds of art and philosophy had been poet's main frame of mind through his entire life. Like Stifter, Niliūnas uses intertextual substitutions and cultural plots. It is probable that with the outbreak of war in Europe and the collapse of stability, to Niliūnas, the connoisseur of books, Stifter’s novel was personally a very significant discovery, becoming one of the pillars of his worldview. The author of the article concludes that Niliūnas was affected by the conceptual layer of the Stifter’s novel—the revolving of the ontologically safe existence.
Implant surface modifications as a prevention method for periprosthetic joint infection caused by Staphylococcus aureus: a systematic review and meta-analysis
Authors: Phatama Krisna Yuarno , Dradjat Respati Suryanto , Mustamsir Edi , Nurhidayati Dwi Yuni , Santosaningsih Dewi , Utomo Dwikora Novembri , Hidayat Mohamad 
Published: November 2022

Abstract. Background: Periprosthetic joint infection is the most common infection due to joint replacement. It has been reported that, over a 5-year time span,
3.7 % of cases occurred annually. This statistic has increased to 6.86 %
over 16 years. Thus, an effective method is required to reduce these
complications. Several strategies such as coating methods with various
materials, such as antibiotics, silver, and iodine, have been reported.
However, the best preventive strategy is still undetermined. Therefore, this
systematic review aims to evaluate the outcome of coating methods on joint
arthroplasty as a treatment or preventive management for infection
complications.
Methods: Eligible articles were systematically searched from multiple
electronic databases (PubMed, Cochrane library, and ScienceDirect) up to 2 June 2022. Based on the criterion inclusion, eight articles were selected for this study. The Newcastle–Ottawa scale (NOS) was used to assess the quality
of the study, and the meta-analysis test was conducted with Review Manager 5.4.
Results: The quality of the articles in this study is in the range of
moderate to good. It was found that the application of modified antibiotic coatings significantly reduced the occurrence of periprosthetic joint
infection (PJI) (p 0.03), and silver coating could not significantly (p 0.47) prevent the occurrence of PJI. However, according to the whole aspect of coating modification, the use of antibiotics, silver, and iodine can minimize the occurrence of PJI (p <0.0001).
Conclusion: Coating methods using antibiotics are an effective method that
could significantly prevent the occurrence of PJI. On the other hand,
coating with non-antibiotic materials such as silver could not significantly
prevent the incidence of PJI.
ANALISIS PENERIMAAN PENGGUNA SISTEM INFORMASI PELAYANAN KANTOR KELURAHAN BERBASIS WEB
Authors: Khoirunnisa Fitri , Roifah Siti , Setiawan Soni 
Published: November 2022

Penggunaan teknologi dalam bidang pemerintahan merupakan suatu keharusan yang harus dilaksanakan. Karena dengan penggunaan sebuah teknologi informasi ini dapat membantu pihak pemerintahan dalam meningkatkan efektifitas, efisiensi, serta penyampaian layananan. Sesuai dengan Undang-Undang No. 6 Tahun 2014 mengenai Desa/Kelurahan Pasal 86 ayat (3) menyatakan bahwa “Sitem Informasi desa/kelurahan sebagaimana yang dimaksud pada ayat (2) meliputi fasilitas perangkat keras dan perangkat lunak, maka dengan demikian diimplementasikanlah sebuah sistem informasi pelayanan kantor kelurahan berbasis web. Maka dilakukanlah analisis kepuasan pengguna terhadap implementasi sistem informasi layanan kelurahan berbasis web ini dengan meggunakan metode Technology Acceptance Model (TAM), dalam penelitian ini variabel yang digunakan yaitu variabel kegunaan persepsi, kemudahan penggunaan dan sikap terhadap pengguna. Hasil dari analisis kepuasan ini yaitu dapat diketahui bahwa pengaruh X1 terhadap Y adalah sebesar 31,2%, pengaruh X2 terhadap Y adalah sebesar 32,7% , dan pengaruh X1 dan X2 secara simultan terhadap Y adalah sebesar 38,5%.
Segregación ocupacional y acoso sexual: la dimensión simbólica de su persistencia
Authors: Moreno Colom Sara , Borràs Català Vicent , Jiménez Carmen , Peidró Lídia 
Published: November 2022

El artículo presenta parte de los resultados del estudio “El acoso sexual y por razón de sexo en el mundo laboral: una aproximación cualitativa”. El objetivo general de dicha investigación fue analizar el trasfondo sociocultural que sustenta la persistencia del acoso sexual y por razón de sexo. Los objetivos específicos incluían: identificar, describir y explicar los factores sociales que perpetúan el fenómeno.
Tomando como punto de partida este estudio, el artículo presenta una aproximación al acoso sexual y a la segregación ocupacional fijándose en la dimensión simbólica de ambas discriminaciones. Para profundizar sobre esta cuestión, se presenta la evidencia empírica obtenida con la realización de ocho grupos de discusión.
Los resultados muestran que los imaginarios socialmente compartidos reflejan el peso de los roles y estereotipos tradicionales de género en el lugar de trabajo configurando dos universos simbólicos, el femenino y el masculino, que coexisten pero no se comunican. Ambas realidades contribuyen a explicar la persistencia de las discriminaciones laborales contra las mujeres.
Cognitive impairment in patients with hypothyroidism and possibilities of its correction
Authors: Chernyadeva E. V. 
Published: November 2022

Aim. To identify and correct cognitive impairment in patients with hypothyroidism.Materials and methods. The study included 76 patients with primary hypothyroidism. All patients were divided into 2 groups: compensated and decompensated hypothyroidism. In addition to general clinical, and hormonal blood tests all participants in the study underwent ultrasound of the thyroid gland and ECG, the neurophysiological study of cognitive evoked potentials, and testing according to the Montreal cognitive function assessment scale.Results. In the majority of patients with a lack of thyroid hormones, cognitive impairments were detected, which increase with worsening compensation for hypothyroidism according to the results of Montreal Cognitive Assessment Scale testing. The study of evoked potentials in patients with hypothyroidism revealed an increase in latency and a decrease in the amplitude of the P300 indicator, indicating the presence of cognitive deficit. The addition of ethylmethylhydroxypyridine succinate to hormone replacement therapy in patients with hypothyroidism significantly improves cognitive performance more than hormone monotherapy.Conclusions. This study showed the need to identify cognitive impairments in patients with primary hypothyroidism, and their correction with the help of complex therapy increases the cognitive potential and the effectiveness of their treatment.
Compost production potential in ecotourism Bukit Cemeng, Bangli
Authors: Posmaningsih D. A. A. , Jana I Wayan , Suiraoka I Putu 
Published: November 2022

Bukit Cemeng is one of the newly opened tourist attractions in Bangli Regency. Waste management is one of the concerns of Bukit Cemeng management. So far, the waste generated is only done by landfilling and burning so as not to pollute the environment. This type of research is study applied with design random group. Sampling units are waste generated in Bukit Cemeng Ecotourism. Research carried out replication as much 3 times for see stability of the manufacturing process compost from organic waste generated in Ecotourism Hill whiny. Based on results study obtained that average heavy waste generated in Bukit Cemeng ecotourism is 7.175 kg, average waste volume is 0.23 m3 and density waste 33.27 kg/m3. There is no difference in the quality of Carbon, Nitrogen and Potassium in the three replications of processing waste into compost, meaning that the resulting Carbon Nitrogen, and Potassium values are stable. There is difference nitrogen quality in three replications processing rubbish it means the Nitrogen value produced no stable. Compost produced at Bukit Cemeng Ecotourism Fulfill requirements quality compost based on SNI 19-7030-2004.
Sostenibilità economica e transizione ecologica: l’apporto giuridico buddhista
Authors: Bilotti Domenico 
Published: November 2022

SOMMARIO: 1. Osservazioni propedeutiche: la crescente rilevanza di un approccio metodologicamente propenso alla riconversione ambientale e alla solidarietà sociale - 2. Caratteristiche generali idonee a proporre le dottrine buddhiste come case study di precipua significatività - 3. Le tracce di una riflessione culturalmente orientata: l’eredità dei maestri canonici - 4. Gli insegnamenti del Buddha come principi di una taumaturgia giuridica interculturale - 5. L’astensione curativa: una nozione rafforzata di condotte omissive - 6. Un bilancio casistico: materiali di studio sui rapporti tra il buddhismo e le istituzioni statali - 7. Possibile conclusione a partire dallo stato dell’arte: il buddhismo tra dottrina, rito e habitus.
Sustainability and environmental transition: the legal Buddhist contribution
ABSTRACT: We are currently experiencing an increasing attention on the economic sustainability and the environmental issues. This process still merely seems a theoretical declaration because its concrete efforts are appearing weak and fragile. The aim of this essay is to underline the possibility of a better comprehension of those sets of problems by studying the spiritual and legal contribution of Buddhism: a not theistic axiology that implies a renewed approach to ecology and economics, able to determine methodological consequences even in the sphere of public law.
I ministri di culto in Italia
Authors: Cavana Paolo 
Published: November 2022

SOMMARIO: 1. La nozione di ministro di culto nell’ordinamento italiano - 2. Origini storiche della figura civilistica del ministro di culto - 3. Principi ispiratori dell’attuale normativa sui ministri di culto - 4. La normativa sui ministri di culto: le fonti - 5. Disposizioni restrittive sui ministri di culto - 6. I ministri di culto nel diritto penale - 7. I ministri di culto nella legislazione pattizia - 8. Ministri di culto e giurisdizione confessionale, tra autonomia e tutela dei diritti - 9. Il sostentamento dei ministri di culto - 10. La remunerazione del ministro di culto: natura della prestazione e tutela giurisdizionale - 11. Le molteplici attività socialmente rilevanti dei ministri di culto - 12. Problemi, vecchi e nuovi, e prospettive di riforma - 13. Osservazioni conclusive.
The ministers of religion in Italian law
ABSTRACT: This contribution analyses the status of ministers of religion in the Italian legal system. It starts from a description of the historical foundations, which lies in Nineteenth-century liberal legislation, and arrives at a synthetic representation of the regulations currently in force in the unilateral State law and in the Concordat and Treaty legislation. The regulatory evolution, which is still in progress, describes the transition from a uniform and homogeneous concept of minister of religion, inspired by the Catholic priest and placed at the basis of a mostly restrictive legislation, to a more articulate and comprehensive one, reflecting the growing confessional pluralism of Italian society and the assertion of the right to religious freedom. This new approach represents the premise for a legislation that increasingly aims at protecting and promoting the status and the manifold activities of ministers of religion, particularly in the context of the strong enhancement of the Welfare State and of the Third sector. Finally, the article focuses on some problematic issues of the current legislation and on the apparent paradox that, in the face of a more favorable State legislation, nowadays the status of the minister of religion, and in particular that of the Catholic priest - who still represents the main reference for Italy’s legislation - is undergoing a strong identity crisis in the ecclesial order, thus posing a series of problems also for society at large.