bluuebunny/crossref_metadata_2025_split huggingface dataset:
Essential nutrient intakes and plasma amino acid concentration in cats with obesity undergoing either complete or partial weight reduction
Authors: German Alexander J. , Woods-Lee Georgiana R.T. , Biourge Vincent , Flanagan John 
Published: November 2022

Abstract
Limited data are available regarding essential nutrient intake during weight reduction in cats with obesity fed a therapeutic diet. Fifty-three cats were included in this non-randomised observational cohort study. Weight loss outcomes and body composition changes were assessed in cats undergoing either complete (44 cats, 81%) or partial (9 cats, 19%) weight reduction. Essential nutrient intake during weight reduction was compared with European Pet Food Industry Federation (FEDIAF) and National Research Council (NRC; MR: minimum requirements; AI: adequate intake; RA: recommended allowance) recommendations. All cats remained healthy losing a median (range) of 23% (10–41%) of starting body weight over 221 days (54–976 days). There were no differences in duration, percentage weight loss or rate of weight loss between cats that underwent a complete versus partial weight loss regimen. However, whilst lean mass decreased significantly in cats undergoing complete weight reduction (before 4.2 kg, 2.6–5.7 kg; after 3.9 kg, 2.8–5.2 kg, P < 0.001), there was no change in cats undergoing partial weight reduction (before 3.4 kg, 2.8–4.7 kg; after 3.4 kg, 2.9–4.6 kg, P = 0.109). Average daily selenium intake was less than NRC AI and RA in 40 cats (75%), and less than FEDIAF recommendation in 31 cats (58%), whilst average daily choline intake was less than NRC MR, NRC RA and FEDIAF recommendations in 20 (38%), 50 (94%) and 48 (91%) cats, respectively. Intakes of phenylalanine/tyrosine and potassium were marginally less than recommendations in a minority (≤ 13%) of cats. No other essential nutrient deficiencies were observed. In conclusion, widespread essential nutrient deficiencies are not observed when purpose-formulated therapeutic diets are used for either partial or complete weight reduction in cats with obesity. Partial weight reduction protocols might minimise lean tissue loss in cats during weight reduction, and can be used for older cats and those with severe obesity.
Social inequality in health in married or cohabiting individuals with cardiovascular disease: a population-based study combining survey and register data
Authors: Sørensen Jes Bak , Friis Karina , Maribo Thomas , Nissen Nina Konstantin , Nielsen Berit Kjaerside , Mejdahl Caroline Trillingsgaard , Thomsen Anne Marie Ladehoff 
Published: November 2022

Abstract
Background.
Cohabitation status and educational attainment affect a number of cardiovascular disease (CVD) risk factors and also CVD incidence and mortality. However, little is known about social inequality in CVD risk factors in married or cohabiting (married/cohabiting) individuals with CVD. Following this married/cohabiting individuals with CVD and low educational attainment may be an overlooked group with an increased risk of recurrent CVD events. The aim of this study was to address social inequality in health among married/cohabiting individuals with CVD by examining educational differences in health behaviour, mental health and health literacy.
Methods.
Register data on CVD and cohabitation status were linked with self-reported health behaviour, mental health and one dimension of health literacy (the ability to understand health information) from the population-based health survey "How are you?" carried out in Central Denmark Region in 2017. Self-reported educational attainment was used as a marker for social position. In total, 20,585 (69%) participants aged 45 years and above completed the questionnaire. The analytical sample in this study consisted of 1,794 married/cohabiting individuals with CVD.
Results.
Married/cohabiting individuals with CVD and low educational attainment had higher adjusted odds for daily smoking (AOR 3.31, 95% CI 1.87;5.87), physical inactivity (AOR 2.10, 95% CI 1.37;3.22), unhealthy diet (AOR 6.37, 95% CI 3.29;12.3) and obesity (AOR 2.55, 95% CI 1.60;4.07) than their high educational attainment counterparts. Furthermore, they had higher levels of perceived stress (Aβ 2.31, 95% CI 1.19;3.43) and lower levels of health literacy (Aβ -0.26, 95% CI -0.36;-0.16) and mental health-related quality of life (Aβ -1.80, 95% CI -3.53;-0.07). Finally, they had lower adjusted odds for moderate/high risk alcohol intake (AOR 0.35, 95% CI 0.20;0.60).
Conclusion.
We found increased CVD risk factors and thus increased risk of recurrent CVD events in married/cohabiting individuals with CVD and low educational attainment compared to married/cohabiting individuals with CVD and high educational attainment. The social inequality in health behaviour, mental health and health literacy among married/cohabiting individuals with CVD should be addressed in both public health strategies, targeted secondary prevention, treatment and rehabilitation.
Many-body reduced vector solution and water vibrations
Authors: Abdel-Rahman A. S. 
Published: November 2022

Abstract
Reduced mass value and vector are well known for the two-body problem, but the many-body reduced vector problem is not solved yet. The study of many-body problems and their applications (such as vibrational spectroscopy) is one of the more important physical problems. Vibrational spectroscopy provides a powerful tool to perceive the molecular structures and atom motions of molecules. The water molecule is a three-body system stretching vibration that has been previously quantized; their frequencies were defined and showed the infrared (IR) absorption spectrum based on Morse potential. In this work, the reduced mass of the many-body problem is being solved and then used to study the intensity of the stretching vibration modes and show the ratio is in agreement with experiments. The molecule was studied in classical and quantum mechanics to determine its absorption intensity as an example of a reduced mass problem. The results show molecular atomic motions and changes in dipole and reduced mass vector. A Morse-like model for bending was predicted based on the spectroscopic vibration frequency and intensity, defining the bending potential depth of 93.5 kJ/mol.
New constraints on axion-like dark matter from a SERF comagnetometer
Authors: Bloch Itay , Shaham Roy , Hochberg Yonit , Kuflik Eric , Volansky Tomer , Katz Or 
Published: November 2022

Abstract
Ultralight axion-like particles are well-motivated relics that might compose the cosmological dark matter and source anomalous time-dependent magnetic fields. We report on new terrestrial bounds from the Noble And Alkali Spin Detectors for Ultralight Coherent darK matter (NASDUCK) collaboration on the coupling of axion-like particles to neutrons and protons. The detector uses nuclei of noble-gas and alkali-metal atoms and operates in the Spin-Exchange Relaxation-Free (SERF) regime, achieving high sensitivity to axion-like dark matter fields. Conducting a month-long search, we cover the mass range of 1.4×10-12 eV/c2 to 2×10-10 eV/c2 and provide world-leading limits which supersede robust astrophysical bounds, and improve upon previous terrestrial constraints by up to two orders of magnitudes for many masses within this range. These are the first reliable terrestrial bounds reported on the coupling of protons with axion-like dark matter, covering a new and unexplored terrain in its parameter space.
Knowledge, Beliefs, and Practices of a Cambodian Traditional Postpartum Medicine, Sra Thnam, among Cambodian Women (15-30 Years) Living in Massachusetts.
Authors: Cordeiro Lorraine S. , Ahnan-Winarno Amadeus D. , Dou Nan , Sibeko Lindiwe , Johns Timothy , Mouth Ronnie , Nelson-Peterman Jerusha 
Published: November 2022

Abstract
Background: Cambodian refugees arrived in the U.S. with limited English proficiency, low educational attainment, poor health status, and significant trauma. Combined with poor healthcare access, this fostered an environment for continued reliance on cultural health practices. Maternal health, including the postpartum period, was particularly influenced by traditional Cambodian medicine. This study investigated associations between sociodemographic factors and Cambodian women’s knowledge, beliefs, and practices related to sra thnam, a traditional postpartum medicine used in the Cambodian diaspora.
Methods: This cross-sectional study was conducted with Cambodian women ages 15-35 years (N=162) living in Massachusetts. A community-academic team developed study materials and administered surveys and focus groups on knowledge, beliefs, and use of sra thnam. Focus group discussions were entered into NVivo 10. Survey data was analyzed using Stata version 14.0 and SPSS version 27. A series of statistical analyses were performed to assess associations between participant use of sra thnam and socio-demographic, health, and psychometric factors.
Results: Knowledge of sra thnam was almost universal (92%), with 44% these participants reporting ever consuming it. Pregnant women (N=56) reported not having consumed sra thnam during the current pregnancy and after childbirth, 52% reported an intention to consume sra thnam, 42.9% did not, and 5.4% were uncertain. After adjusting for covariates, being born in the U.S., having at least one child, older age, and larger households were predictive of ever consuming sra thnam.
Conclusion: These findings show traditional postpartum knowledge and practices are common among Cambodian women living in the U.S. These practices may have benefits, as well as pose some risks, for maternal health. Given that perceptions of pregnancy, childbirth, and postpartum experiences are nested in culture, it is important that healthcare providers are aware of traditional health beliefs and practices in refugee and immigrant communities. Greater understanding of traditional postpartum practices can facilitate culturally relevant support and health care services to mothers.
Identification of PRIM2 as a new prognostic and immune-related marker in cancer based on a comprehensive pan-cancer analysis
Authors: Jiang Jinqun , Lu Hai 
Published: November 2022

Abstract
DNA Primase Subunit 2 (PRIM2) encodes a large subunit (p58C) of DNA primase, which plays an important role in DNA replication. However, the role of PRIM2 in cancer and immune regulation has not been elucidated. Therefore, in the present study, the expression profile of PRIM2 in cancer was investigated using publicly available databases like the Cancer Genome Atlas (TCGA), the Genotype-Tissue Expression (GTEx), the Broad Institute Cancer Cell Line Encyclopedia (CCLE) from the University of California Santa Cruz (UCSC) Xena website. PRIM2 expression was analyzed in paired normal to the adjacent tumor and unpaired cancer and normal tissues. The prognosis of PRIM2 in various cancers was studied using Cox regression and Kaplan-Meier analysis. The relationship between PRIM2 and tumor staging, tumor mutation burden (TMB), and microsatellite instability (MSI) was analyzed. Algorithms like cell type identification by estimating relative subsets of RNA transcripts (CIBERSORT), xCell, ssGSEA, and MCP-counter were used to study the correlation between PRIMA2 and tumor immune microenvironment, immune infiltrating cells, and immune-related genes (antigen processing and presentation genes, chemokines, chemokine receptors, HLA-related genes, immune checkpoints). Further, the correlation between PRIM2 and methyltransferase (DNMT1, DNMT3A, DNMT3B) from different databases. The biological processes and signaling pathways associated with PRIM2 in various tumors were studied. Finally, the correlation between the PRIM2 and the sensitivity of multiple drugs was analyzed using the National Cancer Institute (NCI)-60 database. The results show that PRIM2 was up-regulated in most tumors, high PRIM2 expression was associated with the different stages of cancer, and poor prognosis was observed. The results indicate that PRIM2 could potentially be used as a prognostic and immunotherapy target in tumors.
Predictive factors of egg allergy clinical outcomes in infants and young children
Authors: mo xiaoyan , lv jiajia , shao jie 
Published: November 2022

Abstract
Aim: To explore the tolerance march in children and identify potential factors that affect the prognosis of egg allergy (EA).
Methods: Two hundred children(age range, 6 months-2.5 years)with atopic dermatitis (AD) were recruited from 2018 to 2019. EA was diagnosed based on medical history, skin prick test (SPT), and the oral food challenge (OFC) test. EA was diagnosed in 78 children; among these, 7 were allergic only to egg yolk (Only EYA), 20 to egg white (Only EWA), and 51 to whole egg (WEA). Logistic regression analysis was used to identify risk factors for outcomes during the disease course. Receiver operating characteristic (ROC) curve analysis was performed to establish a predicting model.
Results: The Scoring Atopic Dermatitis score in the WEA group was more severe and persistent than that in the other groups. Forty-three cases of EA developed clinical tolerance (average age, 32.3 ± 8.7 months). The tolerance rate of EYA and EWA was 75.9% and 56.3%, respectively. The SPT wheal diameter at initial diagnosis (SPTdiag) was a risk factor for persistent EA. The SPT wheal diameter after 6 months (△SPT6mo) in the tolerant group was markedly decreased compared to that in the persistent EA group. Tolerance was higher when △EW-SPT6mo ≥ 39.5% or △EY-SPT6mo ≥ 27%.
Conclusion: The initial SPTdiag and SPT6mo values were significantly correlated with and can predict outcomes of EA.
Prevalence and Risk Factors of Lung Worm Infection in Small Ruminants in Selected Districts of Wolaita Zone, Snnprs, Ethiopia
Authors: Tora Ephrem , Tessema Wondimu , Getachew Minale 
Published: November 2022

Abstract
The lungworm is an important parasitic nematode of small ruminants that infects the lower respiratory tract and is associated with high mortality and morbidity. However, the level of lungworm infection in the study districts is not known. A cross-sectional study was conducted from December 2019 to June 2020 in selected Districts of Wolaita Zone with the objectives of determining the prevalence of lungworm infection and associated risk factors. Modified Baermann techniques were used for identification of the lungworms from fecal samples. A total of 742 fecal samples from 443 sheep and 299 goats were collected and examined. Lungworms were detected in 271(36.52%) samples. The parasites infected 192 (43.34%) and 79 (26.42%) of sheep and goats respectively. Lungworm species Dictyocaulus filaria, Protostrongylus rufescens and Muellerius capillaries were identified in 114(15.36%), 68(9.16%) and 57(7.68%) fecal samples respectively. Mixed infection by two or more above species was noted in 32 (4.31%) of the samples. Among the epidemiological factors examined, agro-ecology, management system, and season showed statistically significant differences (P < 0.05) with overall lungworm prevalence in sheep and goats. On the other hand, lungworm infection among sexes, age groups and body condition scores showed no statistically significant difference (P > 0.05). The present study indicated that lungworm infection was a common problem for sheep and goats in the study area. So, measures like de-worming, early treatment and improving animal husbandry should be practiced.
Study on vertical load distribution of pile group-liquefied soil system under horizontal earthquake
Authors: Huang Zhanfang , Bai Lichao , Su Tian , Bai Xiaohong , Zheng Junjie , Liu Yongqiang 
Published: November 2022

Abstract
The dynamic response of pile-liquefied soil is a complex problem. Based on the shaking table test test, the vertical bearing characteristics of pile foundation - liquefied soil system under simulated horizontal seismic force are analyzed and studied with the help of MIDAS GTS three-dimensional finite element analysis software. Study the load borne by the pile top under horizontal earthquake with a certain vertical load, different pile spacing and different vibration time, The cumulative coefficient CCPF of pile side friction is introduced. At different vibration times the distribution of CCPF along the pile body of single pile and pile groups with different pile spacing is analyzed, it is concluded that CCPF can intuitively reflect the distribution law of pile side friction during vibration. When the value of CCPF at the pile bottom is equal to 1, it means that the load actually acting on the pile top is equal to the average value of the total load. When CCPF at the pile bottom is less than 1, it means that the load on the pile top is less than the average value of the total load. When CCPF at pile bottom is greater than 1, it indicates the load on the pile top is greater than the average of the total load.
Responses of photosynthesis and chlorophyll fluorescence during light induction in different seedling ages of Mahonia oiwakensis
Authors: Chen Chung-I , Lin Kuan-Hung , Lin Tzu-Chao , Huang Meng-Yuan , Chen Yung-Chih , Huang Chau-Ching , Wang Ching-Wen 
Published: November 2022

Abstract

Background
The aim of this study was to determine the actual state of the photosynthetic apparatus and exhibit distinguishable differences in the chlorophyll fluorescence (ChlF) components in different seedling ages of M. oiwakensis plants subjected to different light intensity (LI), that reflected their adaptability to their habitats and how they responded to LI changes. Potted 6-month-old greenhouse seedlings and field collected 2.4-year-old seedlings with 5 cm heights were selected and randomly separated into seven groups for photosynthesis measurements illuminated with 50, 100 (assigned as low LI), 300, 500, 1,000 (as moderate LI), 1,500 and 2,000 (as high LI) µmol m–2 s–1 photosynthetic photon flux density (PPFD) treatments.
Results
In 6-month-seedlings, as LI increased from 50 to 2,000 PPFD, the values of non-photochemical quenching and photoinhibitory quecnhing (qI) increased but potential quantum efficiency of PSII (Fv/Fm) and ΦPSII values decreased, indicating adaptation to low LI conditions. High electron transport rate, actual PSII efficiency %, and Fv/Fm% values were observed in 2.4-year-old seedlings at high LI conditions, suggesting that these seedlings can have higher photoprotective ability under high LI treatments to maintain higher photosynthetic system performance. Furthermore, higher ΦPSII was detected under low LI conditions, with lower energy-dependent quenching (qE) and qI values and photo-inhibition % decreased as well. However, qE and qI increased as ΦPSII decreased and photo-inhibition% increased under high LI treatments.
Conclusions
These results could be useful for predicting the changes in growth and distribution of Mahonia species grown in controlled environments and open fields with various combinations of varying light illuminations, and ecological monitoring of their restoration and habitat creation is important for provenance conservation and helps to formulate better conservation strategies.
Beyond consensus sequence: a quantitative scheme for inferring transmission using deep sequencing in a bacterial transmission model
Authors: Senghore Madikay , Read Hannah , Oza Priyali , Johnson Sarah , Passarelli-Araujo Hemanoel , Taylor Bradford , Ashley Stephen , Grey Alexander , Callendrello Alanna , Lee Robyn , Goddard Matthew , Lumley Thomas , Hanage William , Wiles Siouxsie 
Published: November 2022

Abstract
Genomic surveillance provides a data source complementary to contact tracing to resolve putative transmission chains. However, the role of within-host diversity in transmission is understudied due to a lack of experimental and clinical datasets that capture within-host diversity in both donors and recipients. Here, we assess the utility of deep-sequenced genomic surveillance within a mouse transmission model where the gastrointestinal pathogen Citrobacter rodentium was controllably spread during co-housing of infected and naïve animals. We observed that within-host variants were maintained over multiple transmission steps until fixation or elimination. We present a model for inferring the likelihood that a given pair of samples are linked by transmission, by comparing the allelic frequency at variant genomic loci. Our data affirm that within-host single nucleotide variants (iSNVs) can repeatedly pass from donor to recipient along the transmission chain, and the mere sharing of iSNVs between different transmission pairs offers limited confidence in identifying a transmission pair. Beyond the presence and absence of within-host variants, we show that differences arising in the relative abundance of iSNVs can infer transmission pairs with high precision. An important component of our approach is that the inference is based solely on sequence data, without incorporating epidemiological or demographic data for context. Our model, which substantially reduces the number of comparisons a contact tracer needs to consider, may enhance the accuracy of contact tracing and other epidemiological processes, including early detection of emerging transmission clusters.
Diagnostic delay in multiple myeloma: the legacy of the COVID-19 pandemic.
Authors: Carmichael Jonathan , Seymour Frances , Mcilroy Graham , Tayabali Sarrah , Amerikanou Rodothea , Feyler Sylvia , Aung June , Popat Rakesh , Pratt Guy , Parrish Christopher , Ashcroft John , Jackson Graham , Cook Gordon 
Published: November 2022

Abstract
The COVID-19 pandemic has had global healthcare impacts, including high mortality from SARS-CoV-2 infection in cancer patients; individuals with multiple myeloma (MM) are es-pecially susceptible to poor outcomes. However, even for MM patients who avoided severe infection, the ramifications of the pandemic have been considerable. The consequences of necessary socio-geographical behavior adaptation, including prolonged shielding and inter-ruptions in delivery of non-pandemic medical services are yet to be fully understood. Using a real-world dataset of 323 consecutive newly diagnosed MM patients in England, we in-vestigated the impact of the COVID-19 pandemic on routes to myeloma diagnosis, disease stage at presentation and relevant clinical outcomes. We demonstrate increasing MM presentations via emergency services and increased rates of bony and extra-medullary dis-ease. Differences were seen in choice of induction therapy and the proportion of eligible patients undertaking autologous stem cell transplantation. Whilst survival was statistically inferior for emergency presentations, significant survival differences have yet to be demon-strated for the entire cohort diagnosed during the pandemic, making extended follow-up critical in this group. This dataset highlights wide-ranging issues facing MM patients conse-quent of the COVID-19 pandemic, with full impacts for clinicians and policy-makers yet to be elucidated.
Exoplanets Around Red Giants: Distribution and Habitability
Authors: chen Ruixuan , Jiang Jonathan , Rosen Philip , Fahy Kristen , Chen Yanbei 
Published: November 2022

Abstract
As the search for exoplanets continues, more are being discovered orbiting Red Giant stars. We use current data from the NASA Exoplanet Archive to investigate planet distribution around Red Giant stars and their presence in the host’s habitable zone. As well, we update the power law relation between planet mass and stellar radius found in previous studies and provide more detailed investigations on this topic. Ten Red Giant-hosted exoplanets are found to be in the optimistically calculated habitable zone, while five of which are in the conservative habitable zone. We believe additional exoplanets can be found in habitable zones around Red Giants using the direct imaging method and more powerful detection instrumentation.