bluuebunny/crossref_metadata_2025_split huggingface dataset:
Initial experience with 161 extraperitoneal laparoscopic radical cystectomy procedures: Comparison with transabdominal laparoscopic radical cystectomy
Authors: Yang Han , Zhang Zongliang , Zhao Kai , Zhang Yulian , Yin Xinbao , Zhu Guanqun , Wang Zhenlin , Li Xueyu , Li Zhaofeng , Wang Qinglei , Sui Yuanming , Xing Nianzeng , Wang Ke 
Published: November 2022

ObjectivesThere is substantial concern about traditional transperitoneal laparoscopic radical cystectomy (TLRC) due to multiple postoperative complications. In contrast, extraperitoneal laparoscopic radical cystectomy (ELRC) appears to cause a lower rate of morbidity. The present study aimed to compare the efficacy of ELRC and TLRC for bladder cancer (BCa).MethodsThe clinical data of patients undergoing laparoscopic radical cystectomy for BCa from April 2018 to October 2021 were retrospectively analyzed, as ELRC and TLRC groups. The postoperative follow‐up data of 275 patients were collected and the incidence of postoperative complications and other perioperative outcomes were compared between the two groups.ResultsSurgery was successfully completed in all patients without conversion to open surgery. There was no significant difference in the duration of cystectomy surgery (67.32 ± 23.53 vs 72.17 ± 25.72 min, p = 0.106), intraoperative blood loss (178.06 ± 110.4 vs. 174.56 ± 127.40 ml, p = 0.413), or the number of lymph node dissection (15.1 ± 5.7 vs. 14.5 ± 5.1, p = 0.380) between the two groups. The length of stay (11.6 ± 3.8 vs 14.7 ± 5.6 d, p < 0.001), time to resume food intake after surgery (2.3 ± 0.9 vs 3.0 ± 1.3 d, p < 0.001), and the incidence of ileus (p < 0.001) in the ELRC group were significantly lower than in the TLRC group.ConclusionsELRC is a safe procedure that can reduce the incidence of postoperative complications, shorten postoperative hospital stay, reduce the duration of recovery of patients, and, therefore, should be promoted.
Effects of radiofrequency catheter ablation for premature ventricular complexes originating from the right ventricular outflow tract on right ventricular function
Authors: Uhm Jae‐Sun , Ko Kyu‐Yong , Shim Chi Young , Park Je‐Wook , Kim Minkwan , Bae SungA , Jung In Hyun , Kim In‐Soo , Kim Jong Youn , Choi Eui‐Young , Son Won Jeong , Roh Yun Ho , Yu Hee Tae , Kim Tae‐Hoon , Hong Geu‐Ru , Joung Boyoung , Pak Hui‐Nam , Lee Moon‐Hyoung 
Published: November 2022

AbstractIntroductionThis study aimed to elucidate the relationship between premature ventricular complexes (PVCs) and right ventricular (RV) dysfunction, and the effects of radiofrequency catheter ablation (RFCA) on RV function.MethodsA total of 110 patients (age, 50.8 ± 14.4 years; 30 men) without structural heart disease who had undergone RFCA for RV outflow tract (RVOT) PVCs were retrospectively included. RV function was assessed using fractional area change (FAC) and global longitudinal strain (GLS) before and after RFCA. Clinical data were compared between the RV dysfunction (n = 63) and preserved RV function (n = 47) groups. The relationship between PVC burden and RV function was analyzed. Change in RV function before and after RFCA was compared between patients with successful and failed RFCA.ResultsPVC burden was significantly higher in the RV dysfunction group than in the preserved RV function group (p < .001). FAC and GLS were significantly worse in proportion to PVC burden (p < .001 and p < .001, respectively). The risk factor associated with RV dysfunction was PVC burden [odds ratio (95% confidence interval), 1.092 (1.052–1.134); p < .001]. Improvement in FAC (13.0 ± 8.7% and –2.5 ± 5.6%, respectively; p < .001) and GLS (–6.8 ± 5.7% and 2.1 ± 4.2%, respectively; p < .001) was significant in the patients with successful RFCA, compared to the patients in whom RFCA failed.ConclusionsFrequent RVOT PVCs are associated with RV dysfunction. RV dysfunction is reversible by successful RFCA.
Paying for ecological services in Ecuador: The political economy of structural inequality
Authors: McBurney Matthew , Tuaza Luis Alberto , Johnson Craig 
Published: November 2022

AbstractPaying Indigenous communities to conserve land for carbon sequestration is a controversial way of tackling climate change. Critics argue that paying for ecological services (or ‘PES’) in the form of carbon offset programmes reduces land and social relations to an economic transaction that devalues Indigenous livelihoods and communities. At the same time, empirical studies have shown that Indigenous communities have accepted and even embraced the idea of being paid to conserve land for climate change mitigation. This paper explores this apparent contradiction by investigating the implementation of Programa Socio Bosque (PSB), a PES carbon sequestration programme in Ecuador. Drawing upon primary fieldwork in the highland province of Chimborazo, it makes the case that PES programmes need to be understood as form of state power that reconfigures and reinforces the ways in which Indigenous peoples engage with the state. Particularly important in this regard is the role of the state in reinforcing the agrarian conditions under which Indigenous communities use and interpret PES payments while at the same time reconfiguring new forms of land conservation. Empirically, the research reveals important complementarities between the goals of carbon sequestration PES programmes and Indigenous land‐use practices. Methodologically, it highlights the importance of situating the study of PES programmes in a context of land struggles, community–state relations and agrarian change.
Biomass losses and circularity along local farm‐to‐fork: A review of industrial efforts with locally farmed freshwater fish in land‐locked Central Europe
Authors: Mraz Jan , Jia Hui , Roy Koushik 
Published: November 2022

AbstractBiomass losses and circularity of aquaculture farm‐to‐fork are reviewed in this article, taking the example of an economically developed but land‐locked territory in Central Europe. We found that some waste valorization channels of locally farmed and slaughtered fish biomass are already functioning in the region (mostly for pet food, hunting bait). There is neither control nor information on how much local aquaculture farm‐to‐fork losses are upcycled to the local human food chain. Despite most of them qualify in ‘category‐3’ animal by‐products (useable for aquafeed) or preventable losses. Factors to improve farm‐to‐fork resource use efficiency ‘locally’ include: (a) ‘at farm’ (supplementary feeding, captive culture conditions, fat content, breed, rested harvest techniques, harvesting season); (b) ‘towards fork’ (purging duration, acclimatization before slaughtering, stunning efficacy, bleeding and filleting relative to rigour mortis, additive‐based cleaning, pre‐cooling, boned or deboned, grinding or baadering); (c) ‘at fork’ (coating‐ or GRAS additives‐based preservation, packaging, modern hurdle systems, freezing rate, interferences of freezing apparatus or packaging on freezing, storage temperature). From farm‐to‐fork, it is essential to understand that most fish processing by‐products can be made edible or valuable by other means. Better utilization strategies exist via low‐cost value‐added fish products, innovative dishes or utility products (e.g., feedstuff, fertilizers, industrial products, luxury items). Although upcycling to human food chain is priority, technological hurdles (prone to spoilage, bones in product, taste, safety) are associated with edible products but are solvable. More difficult things to overcome are at the fork (culinary industry, communication with society, future generations). Those are reviewed.
Effect of increased serum progesterone on luteal morphology and function, pregnancy, and gestational loss in Nelore cows
Authors: Couto Samuel R. B. , Guerson Yuri B. , Caparelli Nicolas M. P. M. , Andrade João Paulo N. , Jacob Júlio C. F. , Barbero Rondineli P. , Mello Marco R. B. 
Published: November 2022

AbstractThe aim of the present study was to determine the impact of different strategies for increasing the level of serum progesterone (P4) on luteal morphology and function in bovine females. The effects of increasing P4 on pregnancy rate and gestational loss (GL) in Nelore cows subjected to timed artificial insemination (TAI) were also evaluated. A total of 939 cows were divided into three groups: P4LA (n = 305), 150 mg of long‐acting injectable P4 7 days after TAI; GnRH (n = 306), 10 μg of buserelin acetate 7 days after TAI; and control (n = 328), no hormone treatment after TAI. Doppler ultrasound assessments and P4 measurements were performed on days 7 and 16 after TAI. The pregnancy rate and GL as a function of treatment were compared using the SAS GLIMMIX procedure. Corpus luteum (CL) vascular perfusion, volume, and plasma P4 concentration were analysed using the SAS PROC MIXED procedure. No significant difference was found among the treatments in terms of volume, number of pixels, and CL intensity or in the serum P4 concentration at 7 days after ovulation. The CL blood flow at 16 days after ovulation was lower in the P4LA and GnRH groups than that in the control group (p < .01). Serum concentrations of P4 at 16 days after ovulation were higher in the P4LA and GnRH groups than those in the control group (p = .04). A difference in the pregnancy rate (p = .003) and a trend in GL (p = .07) as a function of treatment were found. Overall, long‐acting injectable P4 supplementation on day 7 after TAI or GnRH administration affected CL vascularization and increased the serum concentrations of P4 16 days after ovulation, promoting better pregnancy rates than the control.
When the Ends do not Justify the Means: Learning Who is Predicted to Have Harmful Indirect Effects
Authors: Rudolph Kara E. , Díaz Iván 
Published: November 2022

Abstract
There is a growing literature on finding rules by which to assign treatment based on an individual’s characteristics such that a desired outcome under the intervention is maximised. A related goal entails identifying a sub-population of individuals predicted to have a harmful indirect effect (the effect of treatment on an outcome through mediators), perhaps even in the presence of a predicted beneficial total treatment effect. In some cases, the implications of a likely harmful indirect effect may outweigh an anticipated beneficial total treatment effect, and would motivate further discussion of whether to treat identified individuals. We build on the mediation and optimal treatment rule literatures to propose a method of identifying a subgroup for which the treatment effect through the mediator is expected to be harmful. Our approach is non-parametric, incorporates post-treatment confounders of the mediator–outcome relationship, and does not make restrictions on the distribution of baseline covariates, mediating variables or outcomes. We apply the proposed approach to identify a subgroup of boys in the Moving To Opportunity housing voucher experiment who are predicted to have a harmful indirect effect of housing voucher receipt on subsequent psychiatric disorder incidence through aspects of their school and neighbourhood environments.
A new urban change detection method based on the local G and local spatial heteroscedasticity statistics
Authors: Chen Yuzhou , Tao Ran 
Published: November 2022

AbstractAccurate detection of urban changes is critical for guiding city planning that leads to smart and sustainable development. Few existing methods are able to detect urban changes in a timely manner while preserving great details of spatial heterogeneity. In this article, we propose a new method that combines two spatial statistics, namely the local G and local spatial heteroscedasticity. By jointly analyzing the results of both statistics, we design the Urban Development Index (UDI) to assess the types of urban changes that each spatial unit has been experiencing. Based on the sequences of UDI, we can understand the regional patterns of urban changes by linking to urban morphology. We conduct experiments with both a synthetic dataset and a Rwanda population dataset. The results demonstrate that our method can not only identify completed and ongoing phenomena of urban transition, but also unveil the heterogeneous nature of growth and/or shrinkage inside a city.
Tracheal stent aspergillosis occurring after aortic allograft of the trachea
Authors: Durliat Alix , Locatelli‐Sanchez Myriam , Wallet Florent , Allaouchiche Bernard 
Published: November 2022

AbstractBackgroundAspergillosis is a fungal infection with many clinical forms. Invasive aspergillosis is the most widely known severe manifestation, but other forms can need intensive care.AimOur purpose is to report a case of tracheal aspergilloma and provide a review of the literature concerning endobronchial aspergillus.MethodWe report a case of tracheal aspergilloma causing tracheal obstruction in a patient admitted in the ICU for respiratory distress. The aspergilloma occurred in a tracheal stent implanted during tracheal allograft for tracheal cancer. A combination of local and systemic antifungal was used with successful result.
Optimizing antifungal prophylaxis in allogeneic stem cell transplantation: A cohort study of two different approaches
Authors: Selby Philip R. , Warner Morgyn S. , Peake Sandra L. , Bardy Peter , Hiwase Devendra , Singhal Deepak , Beligaswatte Ashanka , Hahn Uwe , Roberts Jason A. , Yeung David , Shakib Sepehr 
Published: November 2022

AbstractBackgroundLimited consensus exists on the optimal use of antifungal agents to prevent invasive fungal infection in the early post allogeneic hematopoietic stem cell transplant (alloHCT) period, particularly when patients cannot tolerate oral medication administration.MethodsWe undertook a retrospective observational cohort study to assess the tolerability, efficacy, and cost of a new antifungal prophylaxis pathway at a major tertiary alloHCT centre. Patients aged ≥16 years who underwent alloHCT between February 2018 and October 2019 (cohort 1) or between April 2020 and November 2021 (cohort 2) were included. In both cohorts, first line prophylactic therapy was oral posaconazole. The second line drugs where oral therapy was unable to be administered were intravenous voriconazole (cohort 1) versus intravenous posaconazole (cohort 2).ResultsThere were 142 patients enrolled in the study, 71 in each cohort. The proportion of patients remaining on first‐line prophylaxis or progressing to second‐, third‐, and fourth‐line options was 22.5%, 39.4%, 29.6%, and 8.5% in cohort 1 and 39.4%, 59.2%, 1.4%, and 0% in cohort 2, respectively. The frequency of neuropsychiatric adverse events was significantly higher in cohort 1 compared to cohort 2 (49.3% vs. 19.8%,p = .0004). Occurrence of proven and probable fungal infections was not significantly different between cohorts. Antifungal drug expenditure was $359 935 (AUD) more in cohort 1 ($830 486 AUD) compared to cohort 2 ($477 149 AUD).ConclusionThe antifungal prophylaxis pathway used in cohort 2 resulted in reduced antifungal‐associated adverse effects, less patients requiring progression to 3rd and 4th line prophylaxis and reduced antifungal drug costs.image
Red blood cell transfusion is associated with an increased risk of splanchnic vein thrombosis in patients with cirrhosis
Authors: Liu Guanghua , Lei Ping , Liao Chushu , Huang Kangle , Li Lingqian , Cao Youde , Chen Jie 
Published: November 2022

AbstractBackgroundHaemorrhage and coagulation disorders are common complications in cirrhotic patients, which cause blood products transfusion, and mounting evidence suggested that red blood cells (RBCs) were associated with pathologic thrombosis and RBC transfusion increased the risk of venous thromboembolism (VTE).AimsThe aim of the study was to investigate the association of RBC transfusion with splanchnic vein thrombosis (SVT) in cirrhotic patients.Materials & MethodsWe retrospectively reviewed patients with cirrhosis admitted in the Hunan Provincial People's Hospital between January 2010 and September 2020. Demographic data, the development of SVT, blood transfusion product type and RBC transfusion dose were collected. Multivariate logistic regression analyses and propensity matching analysis (PSM) were performed to identify the association between RBC transfusion and development of SVT.ResultsA total of 4479 patients with cirrhosis were enrolled in the study. SVT occurred in 48 (12.4%) cirrhotic patients in RBC transfusion group, and 233 (5.7%) cirrhotic patients in non‐RBC transfusion group. RBC transfusion was significantly associated with an increased risk of SVT (unadjusted odds ratio [OR] 2.345, 95% confidence interval [CI] 1.686–3.262, p < 0.001). Notably, this association remained robust after PSM, and the volume of RBC transfusion was associated with SVT in a dose‐dependent manner.ConclusionThis study suggested that RBC transfusion was associated with an increased risk of SVT in cirrhotic patients. High quality clinical study will be needed to further validate the association between RBC transfusion and SVT.
“I Love What I Do; That’s The Bottom Line”: Theory of Women’s Career Attraction and Retention in Sport Psychology
Authors: Curvey Rena M.G. , White Shannon C. , Englis Myles T. , Jensen Katherine C. , Bosco Marissa K. , Thompson Mikaela E. , Hargons Candice N. , Leavens Samantha N. , Murphy Emily A. 
Published: November 2022

The increasing representation of women in the field of sport psychology in recent years is the direct result of pioneering female practitioners and scholars. Although the contributions of these women are often relegated to the pages of textbooks, the exploration of women’s professional experiences is essential to understanding what sources lead women to engaging in sport psychology. Therefore, the purpose of this study was to generate a theory that explored the factors that influence women’s attraction and retention to sport psychology. An interpretivist–constructivist paradigm and constructivist grounded theory methodology was used to guide semistructured interviews with 17 cisgender female sport psychology practitioners. The findings of this study were used to develop the theory of women’s career attraction and retention in sport psychology. The theory comprised three categories including (a) sources of attraction, (b) training and professional development, and (c) sources of retention. Study findings and professional implications are discussed throughout.
Petrochronologic constraints on Paleozoic tectonics in southern New England
Authors: Hillenbrand* Ian , Williams Michael L. , Jercinovic Michael J. , Heizler Matthew T. , Tjapkes Daniel J. 
Published: November 2022

ABSTRACTThe Appalachian Mountains were formed through multiple phases of Paleozoic orogenesis associated with terrane accretion. The timing, tempo, and significance of each event in New England are obscured by overprinting, the limits of geochronologic tools, and differences between lithotectonic domains. We present new monazite and xenotime geochronology, 40Ar/39Ar thermochronology, and major- and trace-element thermobarometry from major tectonic domains in southern New England and across multiple structural levels. These data show contrasting pressure-temperature-time (P-T-t) paths across tectonic domains and highlight eastward metamorphic overprinting associated with younger tectonic events. Our data and geochemical proxies suggest two major periods of crustal thickening, ca. 455–440 Ma and 400–380 Ma, and a heterogeneous record of thinning/exhumation. Ordovician (Taconic) crustal thickening postdates the interpreted accretion of the Moretown terrane by ~20 m.y. and may have been related to shallow subduction after subduction polarity reversal. Subsequent cooling and exhumation (440–430 Ma) may have been related to the end of the Taconic orogeny and opening of the Connecticut Valley basin. (Neo)Acadian tectono-metamorphism is recognized in accreted terranes of New England and is absent in the Taconic block. Amphibolite- to (high-pressure) granulite-facies metamorphism, slow cooling, and protracted anatexis ca. 400–340 Ma support the existence of a long-lived orogenic plateau in southern New England. Exhumation, which began at 340–330 Ma, may have involved ductile (channel) flow. The boundary between continental Laurentia and accreted terranes has been reactivated at multiple times and is presently manifested as a 12–15 km Moho step. At the latitude of our samples, Alleghanian-age tectonism (ca. 310–285 Ma) was limited to retrograde metamorphism, and relatively minor loading and exhumation in the vicinity of the Pelham dome. Our results highlight the sensitivity of the integrative petrochronologic approach and the transition of the eastern margin of Laurentia from terrane accretion to the formation of a high-elevation plateau.
Whole exome sequencing based identification of a case of cardiofaciocutaneous syndrome type 3: the benefits of new sequencing technology in children with neurodevelopmental delay
Authors: O'Reilly Daniel , Dempsey Sharon , O'Grady Michael Joseph , Yousif Taha Ibrahim 
Published: November 2022

We report the case of a boy with a prolonged diagnostic workup for global developmental delay alongside feeding difficulties, failure to thrive, pulmonary stenosis and macrocephaly. Following a series of diagnostic tests over the first 25 months of life, whole-exome sequencing was performed which diagnosed cardiofaciocutaenous syndrome type 3.Global developmental delay is a common presentation to general paediatric and community paediatric clinics. This prompts the search for an aetiology to describe the child’s constellation of symptoms which often consists of a chromosomal microarray, neuroimaging and investigations for an inborn error of metabolism. With developments in genetic testing such as the reducing cost of clinical exome sequencing or whole-exome sequencing, could these testing strategies offer a more comprehensive first line test?This case not only demonstrates the features of cardiofaciocutaneous syndrome type 3 but the added value of modern genetic technologies in the diagnosis of children with global developmental delay.