bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emerging technologies for selenium separation and recovery from aqueous systems: A review for sustainable management strategy
Authors: Pal Parimal , Malhotra Meenakshi 
Published: September 2022

AbstractSelenium (Se) is known both as an essential micronutrient for human health as well as a toxic element when consumed in excess. This work endeavours to critically review the existing selenium literature over the period 1980–2021, following a systematic sub‐classification into the domains of occurrence, speciation, and existing conventional and advanced technologies, while directing further research towards emerging integrated sustainable recovery strategies. The review reveals that the majority of the conventional and advanced separation techniques eventually lead to secondary pollution rather than offering a complete solution, whereas resource recovery studies from water are very scant. Some of the techniques, being miserably slow, cannot be applied in the situations of the occurrence of excess selenium in drinking water, posing a serious threat to human health. Research efforts have so far been directed mainly at the removal of selenium rather than recovery through processes that have the potential of turning selenium abatement technology into a sustainable one with value addition. Emerging integrated technologies involving resource recovery from waste streams or generated sludge such as physicochemical technologies, biochemical reduction, electro‐biological reduction, and membrane‐based hybrid technologies are presently at a very early development stage. Moreover, the application of studies where Se nanoparticles (SeNPs) ormetal selenides are obtained is very limited, which may be attributed to the particle size, purity, morphology, and challenges involved in their separation. This review evaluates the challenges in separation and resource recovery from contaminated streams and points future research in a new direction.
Bayesian fuzzy clustering‐based routing protocol in heterogeneous wireless sensor network using fractional Border Collie optimization
Authors: Sangeetha Shanmugam , Victoire Aruldoss Albert , Shanthakumar Palanisamy 
Published: September 2022

SummaryThe major complex issues of routing protocols in heterogeneous wireless sensor network (WSN) are energy balancing and energy efficiency. Though numerous protocols exist in WSN for routing, increasing the system lifetime and to balance the energy consumption still pose a difficult task in the networking scenario. To solve the energy balancing issues and to prolong the network lifetime, an effective routing protocol is designed using the proposed fractional Border Collie optimization (FBCO) algorithm. The proposed FBCO is derived by incorporating fractional calculus (FC) with Border Collie Optimization (BCO), respectively. To make the routing process more efficient, it is significant to group the nodes in the form of cluster such that the formation of cluster is made using Bayesian fuzzy clustering (BFC). The fitness function is designed by taking into account the multiobjective constrictions, like distance, delay, latency, route link time (RLT), and energy. With these objective factors, the optimal value is computed for each solution in the search space such that the computation of the optimal value enables the routing protocol to enhance energy consumption and network lifespan. The performance achieved by the introduced FBCO‐based routing procedure based on delay is 0.3470 s, latency is 0.3142 s, throughput is 97.58%, and residual energy is 0.1726 J by considering 100 numbers of nodes.
Assessing potassium levels in critically ill patients with heart failure: application of a group‐based trajectory model
Authors: Lin Zehao , Zheng Jiawei , Liu Xiaochun , Hu Xiaojun , Fuxian Ren , Gao Dengfeng 
Published: September 2022

AbstractAimsAbnormalities in potassium homeostasis are frequently seen in hospitalized patients. A poor outcome in heart failure (HF) has been linked to both hypokalaemia and hyperkalaemia. The studies on the connection between variations in potassium levels and all‐cause mortality remain scarce. We delineated trajectories of potassium levels and investigated the association of these trajectories with all‐cause mortality of critically ill patients with HF.Methods and resultsA retrospective analysis of blood potassium levels (9 times) in patients with HF after being admitted to the intensive care unit (ICU). Potassium levels were divided into three groups according to the first serum potassium level in ICU and thereafter categorized as follows: hypokalaemia group (n = 336) (<3.5 mmol/L), normal blood potassium‐level group (n = 3322) (3.5–5.0 mmol/L), and hyperkalaemia group (n = 395) (>5.0 mmol/L). According to the group‐based trajectory modelling (GBTM), the hyperkalaemia group and the normal blood potassium‐level group can be divided into three trajectory groups: the low‐level stable group, the medium‐level stable group, and the high‐level decline group. The hypokalaemia group can be divided into two trajectory groups: the low‐level rise group and the high‐level rise group. A total of 4053 HF patients were included (mean age 71.81 ± 13.12 years, 54.90% males, 45.10% females). After adjusting for possible confounding variables, in the hyperkalaemia group, the low‐level stable group had lower 28 day [high‐level decline group vs. low‐level stable group hazard ratio (HR), 95% confidence interval (CI): 2.917, 1.555–5.473; P < 0.05] and 365 day (high‐level decline group vs. low‐level stable group HR, 95% CI: 2.854, 1.820–4.475; P < 0.05) all‐cause mortality. In the normal blood potassium‐level group, the medium‐level stable group had lower 28 day (medium‐level stable group vs. low‐level stable group HR, 95% CI: 0.776, 0.657–0.918; P < 0.05) and 365 day (medium‐level stable group vs. low‐level stable group HR, 95% CI: 0.827, 0.733–0.934; P < 0.05) all‐cause mortality. In the hypokalaemia group, the cumulative survival of the high‐level rise group and the low‐level rise group did not differ significantly.ConclusionsCritically ill patients with HF have blood potassium trajectories. And the trajectories are associated with all‐cause mortality for hyperkalaemia and normal blood potassium‐level patients. GBTM is a granular method to describe the evolution of blood potassium, which may increase the current knowledge of blood potassium‐level adjustment.
Aetiology of chronic heart failure in patients from a super‐aged society: the KUNIUMI registry chronic cohort
Authors: Fujimoto Wataru , Toh Ryuji , Takegami Misa , Imanishi Junichi , Hamana Tomoyo , Odajima Susumu , Takemoto Makoto , Kuroda Koji , Hatani Yutaka , Yamashita Soichiro , Iwasaki Masamichi , Inoue Takumi , Okamoto Hiroshi , Todoroki Takafumi , Okuda Masanori , Hayashi Takatoshi , Konishi Akihide , Tanaka Hidekazu , Shinohara Masakazu , Nagao Manabu , Murata Shunsuke , Ogata Soshiro , Nishimura Kunihiro , Hirata Ken‐ichi 
Published: September 2022

AbstractAimsWith the rapidly increasing ageing population, heart failure is an urgent challenge, particularly in developed countries. The study aimed to investigate the main aetiologies of chronic heart failure in a super‐aged society.Methods and resultsThe KUNIUMI registry chronic cohort is a community‐based, prospective, observational study of chronic heart failure in Awaji Island, Japan. Inhabitants of this island aged ≥65 years accounted for 36.3% of the population. In the present study, data from patients with symptomatic heart failure were extracted from the registry. A total of 1646 patients were enrolled from March 2019 to March 2021, accounting for ~1.3% of the inhabitants of Awaji Island. We analysed 852 patients with symptomatic heart failure. The mean age was high (78.7 ± 11.1 years), with 357 patients (41.9%) being female. The proportion of women increased significantly with advancing age and constituted more than half of the patients aged 85 years and older (P < 0.01). The prevalence of atrial fibrillation, and in particular long‐standing persistent atrial fibrillation, increased at 70 years of age (P < 0.01). The proportion of patients with heart failure with preserved ejection fraction increased to ~60% when age was over 75 years. Although ischaemic heart disease accounted for 35.0% of chronic heart failure aetiologies, valvular heart disease was the most common cause of chronic heart failure (49.8%). The major types of valvular heart disease were mitral regurgitation and tricuspid regurgitation (27.2% and 21.7%, respectively), both of which increased significantly with age (P < 0.01). The incidence of aortic valve stenosis increased markedly over the age of 85 years (P < 0.01). Atrial functional mitral regurgitation increased with age and was the major cause of mitral regurgitation in patients aged >75 years. Patients with atrial functional mitral regurgitation had a higher prevalence of atrial fibrillation (especially long‐standing persistent atrial fibrillation) and a larger left atrial volume index when compared with patients with other types of mitral regurgitation (P < 0.001, respectively).ConclusionsThe KUNIUMI registry chronic cohort showed a change in heart failure aetiology to valvular heart disease in a super‐aged society. Effective and comprehensive countermeasures are required to prepare for the rapid rise in heart failure incidence in a super‐aged society.
On the predicted replicability of two decades of experimental research on system justification: A Z‐curve analysis
Authors: Sotola Lukas K. , Credé Marcus 
Published: September 2022

AbstractWe examine the predicted replicability of experimental research on system justification theory (SJT) by conducting a z‐curve analysis. Z‐curve is a meta‐analytic technique similar to p‐curve, but which performs better under conditions of heterogeneity. It estimates the predicted replication rate, average power, false discovery risk, and file drawer ratio (FDR) of a sample of studies. The z‐curve based on 116 papers and 232 unique samples suggests that the experimental SJT literature is likely to show low rates of replicability, as indicated by an overall average statistical power of 16%. Moderator analyses suggest that this may be driven in part by publication pressures, that the replicability of research in this area has improved since 2015, and that studies using system threat manipulations show particularly low estimated replication rates (ERR). Implications for the replicability and validity of the experimental SJT literature are discussed, and recommendations to increase the rigor of research are put forth.
Case report: Joint deformity associated with systemic lupus erythematosus
Authors: Chen Shu‐Lin , Zheng Hui‐Juan , Zhang Li‐Yu , Xu Qiang , Lin Chang‐Song 
Published: September 2022

AbstractObjectiveTypically, Jaccoud arthropathy (JA) is characterized by joint deformation without bone erosion. However, some recent studies have shown that bone erosion also occurs in JA; however, this remains controversial. To date, there have been no unified diagnostic standards for JA. Herein, we report a case of systemic lupus erythematosus complicated with JA without bone erosion.MethodsA 27‐year‐old woman was admitted to our department with a 2‐year history of pain, swelling, and progressive deformities of her hands and feet. She was diagnosed with systemic lupus erythematosus and class V lupus nephritis 5 years prior. Upon examination, her erythrocyte sedimentation rate and C‐reactive protein levels were found to be increased. She was positive for antinuclear antibodies, antidouble stranded DNA antibodies, and antiextractable nuclear antigen antibodies, with a decreased complement C3 and C4. Radiography and magnetic resonance imaging revealed no bone erosion. The patient was diagnosed with JA. She was treated with oral prednisone (10 mg daily), tofacitinib (5 mg twice daily), methotrexate (10 mg weekly), and celecoxib (0.2 g twice daily).ResultsThe patient's joint symptoms improved after treatment. No further progress was observed during the 4‐month follow‐up period.ConclusionWe believe that bone erosion is the key to distinguish rhupus syndrome from JA. However, this needs to be confirmed with further long‐term follow‐up studies. We found that the use tofacitinib, MTX, and celecoxib in combination with prednisone may be an effective regimen for the treatment of JA.
Efficacy of combination of transcervical Foley catheter and sublingual misoprostol versus sublingual misoprostol for labor induction in pre‐eclampsia at 28–34 weeks
Authors: Sharma Jyotsna , Sagili Haritha , Keepanasseril Anish 
Published: September 2022

AbstractObjectiveTo compare the efficacy of using a combination of transcervical Foley catheter and sublingual misoprostol with sublingual misoprostol alone for induction of labor (IOL) in women with pre‐eclampsia between 28 and 34 weeks of pregnancy.MethodsThis randomized controlled trial was conducted on women with pre‐eclampsia at 28–34 weeks of pregnancy, with unfavorable cervix, admitted to a tertiary hospital in south India. They were randomized to receive either a combination of transcervical Foley catheter and sublingual misoprostol, or sublingual misoprostol alone. Vaginal birth within 24 h of induction, induction to delivery interval, and neonatal morbidity/mortality were the main outcome measures.ResultsVaginal birth within 24 h was higher with the combination of Foley catheter and sublingual misoprostol compared with sublingual misoprostol alone (60% versus 41.4%, P = 0.028). Overall vaginal delivery rates were comparable between the groups (90% versus 80%, P = 0.051). There was no difference in number of doses of misoprostol, and induction to delivery interval between groups. After excluding those with lower likelihood of neonatal survival, live birth rates, mean birth weight, and neonatal intensive care unit admission rates were similar in both groups.ConclusionsCombination of transcervical Foley catheter and sublingual misoprostol was found to be more effective in achieving vaginal birth within 24 h compared with sublingual misoprostol for IOL in pre‐eclampsia between 28 and 34 weeks of pregnancy.Trial Registration NumberCTRI/2018/09/015766; http://ctri.nic.in/Clinicaltrials/pmaindet2.php?trialid=27984.
A systematic literature review on preventing violent extremism
Authors: Amit Sajid , Kafy Abdulla ‐ Al 
Published: September 2022

AbstractIntroductionIn recent years, violent extremism (VE) attacks have escalated worldwide. More schools and students are being attacked. Examining and addressing VE core causes through preventing VE (PVE) strategies can help avoid future atrocities. Due to the tremendous proliferation of research geared toward PVE, an extensive but disorganized knowledge review has accumulated in recent years. The review aims to discover several common themes and strategies across different disciplines and suggests resilience approaches might be the effective framework for PVE worldwide.MethodsThis study followed the guidelines provided by PRISMA. A systematic literature review on 81 articles was conducted in January 2022, with a screening approach starting from the title, abstract and finally, full articles.ResultsSeventeen studies were identified with a total sample of 2415 vulnerable young adults, age range: 16–29, male: 68.65% and female 31.35% mainly influenced VE pursuits through internet, TV and social media. In addition, the study identified that for PVE, individual actions would include ineffective approaches compared to a group approach starting from family to educational institutions.ConclusionsThe effective PVE will be ensured by developing strategies for resilient individuals and dialoguing from the social‐ecological perspective for taking practical actions in reducing VE activities.
Identification of blood species based on surface‐enhanced Raman scattering spectroscopy and convolutional neural network
Authors: Chen Jiansheng , Wang Peng , Tian Yubing , Zhang Rui , Sun Jiaojiao , Zhang Zhiqiang , Gao Jing 
Published: September 2022

AbstractThe identification of blood species is of great significance in many aspects such as forensic science, wildlife protection, and customs security and quarantine. Conventional Raman spectroscopy combined with chemometrics is an established method for identification of blood species. However, the Raman spectrum of trace amount of blood could hardly be obtained due to the very small cross‐section of Raman scattering. In order to overcome this limitation, surface‐enhanced Raman scattering (SERS) was adopted to analyze trace amount of blood. The 785 nm laser was selected as the optimal laser to acquire the SERS spectra, and the blood SERS spectra of 19 species were measured. The convolutional neural network (CNN) was used to distinguish the blood of 19 species including human. The recognition accuracy of the blood species was obtained with 98.79%. Our study provides an effective and reliable method for identification and classification of trace amount of blood.
Highlighting nuances of blue light phototherapy: Mechanisms and safety considerations
Authors: Uzunbajakava Natallia E. , Tobin Desmond J. , Botchkareva Natalia V. , Dierickx Christine , Bjerring Peter , Town Godfrey 
Published: September 2022

AbstractThe efficacy of blue light therapy in dermatology relies on numerous clinical studies. The safety remains a topic of controversy, where potentially deleterious effects were derived from in vitro rather than in vivo experiments. The objectives of this work were (1) to highlight the nuances behind “colors” of blue light, light propagation in tissue and the plurality of modes of action; and (2) to rigorously analyze studies on humans reporting both clinical and histological data from skin biopsies with focus on DNA damage, proliferation, apoptosis, oxidative stress, impact on collagen, elastin, immune cells, and pigmentation. We conclude that blue light therapy is safe for human skin. It induces intriguing skin pigmentation, in part mediated by photoreceptor Opsin‐3, which might have a photoprotective effect against ultraviolet irradiation. Future research needs to unravel photochemical reactions and the most effective and safe parameters of blue light in dermatology.
Plasmapheresis compared with conventional treatment for hypertriglyceridemia‐induced acute pancreatitis: A systematic review and meta‐analysis
Authors: Yan Li‐Hong , Hu Xin‐Hui , Chen Ruo‐Xin , Pan Ming‐Ming , Han Yu‐Chen , Gao Min , Liu Hong 
Published: September 2022

AbstractBackgroundThe treatment of acute pancreatitis (AP) induced by hypertriglyceridemia (HTG) remains controversial with regard to plasmapheresis vs conventional treatment. We reviewed relevant articles to explore the efficacy of plasmapheresis in the management of HTG‐induced AP.MethodsWe systematically reviewed studies that compared plasmapheresis with conventional treatment for HTG‐induced AP using three databases: PubMed, Embase, and Cochrane Library, as well as relevant references. The primary outcomes were 24 h triglyceride reduction rate and in‐hospital mortality.ResultsA total of 791 articles were retrieved. Finally, 15 observational studies (1080 participants) were included, most of which were historical cohort studies. Compared with conventional treatment, plasmapheresis assisted in the reduction of serum triglyceride (TG) levels in the first 24 h after hospital admission (standardized mean difference [SMD]: 0.58; 95% confidence interval [CI]: 0.17 to 0.99; P = 0.005). However, it resulted in increased hospitalization costs (thousand yuan) (weighted mean difference [WMD]: 24.32; 95% CI: 12.96 to 35.68; P < 0.001). With regard to in‐hospital mortality, although the mortality rate in the plasmapheresis group was higher than that in the conventional treatment group (relative risk [RR]: 1.74; 95% CI: 1.03 to 2.94; P = 0.038), the result was disturbed by confounding factors as per the subgroup and sensitivity analysis, as well as trial sequential analysis (TSA). No significant differences were found in other outcomes, including systematic complications, local complications, the requirement for surgery, and hospitalization duration.ConclusionThe effect of plasmapheresis in HTG‐induced AP is not superior to that of conventional treatment, even resulting in a greater economic burden to patients and health care system. High quality randomized control trials are required to obtain a more a definitive understanding of this issue.
Branched polyethyleneimine: CHARMM force field and molecular dynamics simulations
Authors: Terteci‐Popescu Andrada‐Elena , Beu Titus Adrian 
Published: September 2022

AbstractPolyethyleneimine (PEI), one of the non‐viral vectors of great interest for gene delivery, was investigated at all‐atom level, with particular emphasis on its branched form. We report the extension of our previously published CHARMM force field (FF) for linear PEI, with parameters optimized specifically for branched configurations. A new residue type for the branch connector is introduced and the charges and bonded parameters are derived from ab initio calculations based on a model polymer. The new FF is validated by extensive molecular dynamics simulations of solvated branched PEIs of various protonation fractions and branch lengths. The gyration radii, end‐to‐end distances, and diffusion coefficients are compared with results for linear PEIs of similar molecular weights and protonation patterns. Solvated complexes of DNA with (linear/branched) PEI were also investigated to determine favorable attachment conformations. The parametrized atomistic force field is suitable for simulations of PEI with arbitrary branching pattern, protonation, and size, and is expected to provide relevant insights regarding optimal conditions for DNA‐PEI complex formation.
Applications of quinoxaline‐bridged bis(benzimidazolium) salts as ligand sources for the palladium‐catalyzed Suzuki and Heck cross‐coupling reactions in an aqueous medium
Authors: Düşünceli Serpil Demir , Şahan Mehmet Hanifi , Kaloğlu Murat , Üstün Elvan , Özdemir İsmail 
Published: September 2022

AbstractIn the present work, quinoxaline‐bridged bis(benzimidazolium) salts were prepared by the reaction of 2,3‐bis(bromomethyl) quinoxaline and 1‐substituted benzimidazole. The structures of the bis(benzimidazolium) salts were characterized by NMR, FT‐IR, and elemental analysis techniques. Also, the photophysical properties of salts were investigated by UV–Vis absorption and fluorescence emission spectroscopy. Next, these quinoxaline bridged bis(benzimidazolium) salts were used as bidentate benzimidazol‐2‐ylidene ligand precursors in the palladium‐catalyzed Suzuki‐Miyaura and Mizoroki‐Heck cross‐couplings. These salts exhibited moderate‐to‐high activity in the palladium‐catalyzed cross‐coupling reactions.
Comparing the clinical application of strain elastography and shear wave elastography for the evaluation of lateral epicondylitis
Authors: Hong Sujin , Hahn Seok , Yi Jisook , Park Eun Joo , Bang Jin‐Young 
Published: September 2022

AbstractPurposeThis study aimed to compare the diagnostic performance of gray‐scale ultrasound (GSU), strain elastography (SE), and shear wave elastography (SWE) for lateral epicondylitis (LE).MethodsFrom November 2018 to March 2021, 87 common extensor tendons (CETs) of 70 patients were evaluated using elbow ultrasound. Patients were divided into two groups: patients with LE and those without lateral elbow pain. GSU, SE, and SWE findings from the two groups were compared, and the diagnostic performance was compared for significant variables.ResultsAmong the 70 patients, 41 with 44 CETs were clinically diagnosed with LE, and 29 with 43 CETs had no lateral elbow pain. Hypoechogenicity, calcification, and hyperemia were significantly different. Strain ratio (SR), stiffness, and shear wave velocity (SWV) were also significantly different. The diagnostic accuracy of stiffness and SWV was better than that of other significant findings. Furthermore, there were no superiorities in SR, stiffness, or SWV.ConclusionBoth SE and SWE can be valuable diagnostic tools for diagnosing LE. The diagnostic performances of both SE and SWE were similar in the detection of LE.