bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of occupational therapy interventions on function and satisfaction with occupational performance among adults with conditions of the hand, wrist, and forearm: a protocol for a systematic review
Authors: Sheerin Margo , O' Riordan Cliona , Conneely Mairead , Carey Leonora , Ryan Damien , Galvin Rose , Morrissey Ann-Marie 
Published: August 2022

Background: Functional hand use post injury is important in enabling a person’s engagement in daily living tasks. Without proper treatment, there may be difficulties in self-care, engaging in job roles, or leisure pursuits. Occupational therapists are key health care practitioners for people with upper limb conditions. This systematic review aims to appraise and summarise current evidence regarding effectiveness of occupational therapy interventions among adults with conditions of the hand, wrist, and forearm. Methods: A systematic review of randomised control trials and quasi randomised controlled trials will be completed. MEDLINE OVID, CINAHL, CENTRAL, COCHRANE, PUBMED and EMBASE databases will be systematically searched. Grey literature will be searched for via Google Scholar. Studies will be included if they include provision of occupational therapy to adults with a hand, wrist, or forearm condition when compared to treatment as usual or an alternative treatment option. The primary outcome will be function. Secondary outcomes will include satisfaction with occupational performance, quality of life, pain experience, and participation. The Brief International Classification of Functioning, Disability and Health (ICF) Core Set for Hand Conditions will be used to categorise outcomes. The Cochrane Risk of Bias 2 (RoB 2) tool and the Grading of Recommendations Assessment, Development, and Evaluations (GRADE) framework will be utilised to assess quality. A pooled meta- analysis will be completed using RevMan, depending on the uniformity and availability of data. Results: This review aims to synthesise high quality evidence to identify the effectiveness of occupational therapy interventions with patients with a hand, wrist, or forearm condition, categorising outcomes in relation to the ICF Core Set for Hand Conditions. Conclusions: By synthesising the evidence there is potential for improved evidence base for clinicians; improved outcomes for patients; as well as potential economic benefit. This study is registered with PROSPERO: CRD42022337070.
Intention and motivation to pursue higher education among registered nurses and midwives: a cross-sectional study during COVID-19
Authors: Nashwan Abdulqadir J. , Villar Ralph C. , Mathew Rejo G. , Al-Lobaney Nabeel F. , Nsour Ahmad T. , Abujaber Ahmad A. , Leighton Kim 
Published: August 2022

Abstract

Objectives
To determine the intention and motivation of nurses and midwives to pursue their higher education considering several factors.

Methods
This is a cross-sectional study were a 16-item online survey was distributed using a convenience sampling method to approximately 12,000 nurses and midwives between May – July 2021.

Results
A total of 513 eligible nurses and midwives participated in the study. Most of the respondents were females (76.61%), with a bachelor’s degree (72.3%) and well experienced (11–15 years) (35.4%). Most nurses and midwives are highly motivated to pursue higher education (79.14%). The most motivating factor for the respondents is their professional goals (85.2%), While the most dissuading factor was the cost. Regarding COVID-19, about 28% of the respondents said that the COVID-19 pandemic has a negative effect on their desire to go for higher education.

Conclusions
The nurses and midwives were highly motivated to pursue higher education regardless of their demographic status, available resources, and barriers. Furthermore, the eagerness of the nurses and midwives to pursue higher education, which is rooted in their desire to grow in their profession.
Paroxysmal atrial fibrillation and the left heart structure and function in hypertensive patients
Authors: Mazur E. S. , Mazur V. V. , Bazhenov N. D. , Nilova O. V. , Burova S. A. 
Published: August 2022

Objective. To identify the features of the left heart structure and function in patients with hypertension (HTN) and new onset paroxysmal atrial fibrillation (AF).Design and methods. We included HTN patients with left ventricular hypertrophy and valid 24-hour Holter monitoring carried out over the last month. Patients without AF paroxysms (age from 37 to 82 years, 38,4% men) were divided into two groups: the 1st group included 32 patients under 55 years of age, the 2nd group comprised 63 patients 55 years of age and older. Thirty-eight patients with AF paroxysms were included in the 3rd group (age from 56 to 74 years, men 28,9%). The parameters of the left heart structure and function, including the global longitudinal strain of the left ventricle and the left atrium strain in the reservoir and contraction phases, were assessed by echocardiography.Results. The average age of patients in the groups was 44,7 46,4 48,2 vs 61,9 63,7 65,4 vs 63,4 64,8 66,2 years (p < 0,001), and the average duration of HTN was 3,2 4,35,6 vs 6,9 7,99,1 vs 5,7 6,98,1 years (p < 0,001), respectively. The moderate and severe left ventricular hypertrophy and the diastolic dysfunction were found significantly less frequently in the 1st group than in other groups (5,0 12,528,1% vs 43,3 55,667,8% vs 36,8 52,668,5%, p < 0,001 and 5,2 18,832,3% vs 51,6 63,575,4% vs 53,6 68,483,2%, p < 0,001). In 1st group, the left atrial reservoir strain was higher than in the 2nd group, and in the 2nd group it was higher than in the 3rd group (24,7 26,3 28,0 vs 21,5 22,7 23,9 vs 17,8 19,2 20,5, p < 0,001). The left atrial contraction strain did not differ in the 1st and 2nd groups and it was higher than in the 3rd group (13,8 14,9 16,0 and 12,9 13,6 14,2 vs 9,6 10,3 11,1, p < 0,001). The multivariate logistic regression analysis showed that the left atrial strain in the contraction phase is a predictor of AF occurrence in HTN patients over 55 years old depends on. The chances of AF detecting in these patients increase by 3,122 9,21127,171 times (p < 0,001), if the left atrial strain in the contraction phase is below 13%.Conclusions. The left atrial strain in HTN patients with paroxysmal AF are significantly lower than in patients without cardiac arrhythmias independently of age and the left ventricular state. The left atrial contraction strain ≤ 13% is a predictor of the detection of AF paroxysms during 24-hour Holter monitoring in HTN patients aged 55 years and older.
Antihypertensive therapy in patients with concomitant chronic obstructive pulmonary disease
Authors: Khaisheva L. A. , Glova S. E. , Shlyk S. V. 
Published: August 2022

Objective. Evaluation of the effectiveness and safety of antihypertensive therapy with a fixed dose combination of amlodipine/indapamide in patients with hypertension (HTN) and chronic obstructive pulmonary disease (COPD).Design and methods. We conducted a non-randomized, open, single-center study, which included 74 comorbid patients (62 men, 12 women) with stage I–II HTN, grade 1–2 HTN, moderate cardiovascular risk and COPD (GOLD I–III). We also assessed respiratory function, the parameters of the microcirculatory bed, vascular stiffness, level of tumor necrosis factor α (TNF-α). For HTN, after the examination all patients were prescribed a fixed combination of amlodipine and indapamide (Arifam, Les Laboratoires Servier, France). The observation period was 6 months.Results. The study was completed by 58 patients who achieved blood pressure (BP values of 132,7 + 4,8 mm Hg), 54% patients took the initial dose of amlodipine/indapamide was 5/1,5 mg and in 46% patients, the dose of the drug was increased to 10/1,5 mg. After 6 months of treatment, a statistically significant increase in forced expiratory volume in 1st second (FEV1) was detected (p < 0,05), decrease in the average linear velocity along the maximum velocity curve (p < 0,05), Purcelo peripheral resistance index (p < 0,05), pulse wave propagation velocity in the elastic arteries, which was increased at the beginning of the study (p < 0,05), TNF-α (p < 0,05).Conclusions. The administration of a fixed combination of amlodipine/indapamide in patients with COPD and HTN leads to the achievement of target BP levels, reduction of vascular stiffness, reduction in TNF-α level, improvement of microcirculatory blood flow. The combination is safe and well-tolerated.
Analisis pengaruh faktor makroekonomi dan karakteristik bank terhadap profitabilitas bank syariah di Indonesia
Authors: Dwinanda Safira Kurnia , Tohirin Achmad 
Published: August 2022

Abstract
Purpose – This study aims to analyze the effect of macroeconomic factors and bank characteristics on the profitability of Islamic banks in Indonesia.
Methods – This study analyzes ten Islamic commercial banks in Indonesia in the first quarter of 2010 to the second quarter of 2019 using the Panel Data model.
Findings – The results of this study indicate that external factors have no effect on the profitability of Islamic banks while internal factors have an influence on the profitability of Islamic banks.
Implication – The results of this study have implications for financial ratios as indicators that can measure the extent to which the performance and performance of Islamic banks and Islamic banks need to maintain any increase in operational costs that must be followed by an increase in operating income.
Originality – This study analyzes the impact of external and internal bank factors that affect the profitability of Islamic banks in Indonesia and uses a Data Panel approach.

Abstrak
Tujuan – Penelitian ini bertujuan untuk menganalisis pengaruh faktor makroekonomi dan karakteristik bank terhadap profitabilitas bank syariah di Indonesia.
Metode – Penelitian ini menganalisis sepuluh bank umum syariah di Indonesia pada periode kuartal I 2010 sampai dengan kuartal II 2019 dengan menggunakan model Data Panel.
Temuan – Hasil penelitian ini menunjukkan bahwa faktor eksternal tidak berpengaruh terhadap profitabilitas Bank Syariah sementara itu faktor internal memiliki pengaruh terhadap profitabilitas Bank Syariah.
Implikasi – Hasil penelitian ini berimplikasi terhadap rasio keuangan merupakan indikator yang dapat mengukur sejauh mana performa dan kinerja bank syariah dan Bank syariah perlu menjaga setiap kenaikan biaya operasional yang harus diikuti dengan peningkatan pendapatan operasionalnya.
Orisinalitas – Penelitian ini menganalisis dampak faktor eksternal dan internal Bank yang mempengaruhi profitabilitas Bank Syariah di Indonesia dan menggunakan pendekatan Data Panel.
Inequality repercussions of financing negative emissions
Authors: Andreoni Pietro , Emmerling Johannes , Tavoni Massimo 
Published: August 2022

Abstract
Negative emission technologies are attracting the interest of investors in the race to make them effective and profitable. When deployed at scale, negative emissions will need to be financed through carbon tax revenues or issuing other taxes. Financing negative emissions could thus reduce the fiscal resources needed for a socially inclusive transition. Moreover, if negative emissions are privately owned their profits will disproportionally benefit investors and equity holders. We quantify the inequality repercussions of negative emission through an integrated assessment model which features within-country income heterogeneity and direct air capture of CO2. We find that negative emissions technologies deployed by private actors contribute to more than half of the increase in income inequality observed in a 1.5°C scenario. The effects are concentrated around the time of net-zero and are higher in scenarios with carbon budget overshoot. We attribute regional variations to two main mechanisms, the revenue drying and private ownerships effects of negative emissions.
Modern ideas about the etiology, pathogenesis, diagnosis and treatment of chronic nonspecific cervicitis
Authors: Odyvanova A. A. , Mezhevitinova E. A. , Prilepskaya V. N. , Donnikov A. E. , Uruymagova A. T. , Abakarova P. R. , Nazarova N. M. , Dovletkhanova E. R. , Gusakov K. I. , Kepsha M. A. 
Published: August 2022

Currently, cervicitis of nonspecific etiology is one of the urgent problems of modern gynecology due to the extremely high frequency of their occurrence, a tendency to a chronic relapsing course, a negative impact on reproductive health, and the risk of developing a number of complications. The role of violations of vaginal microbiocenosis and local immune status in the development of CNC has been convincingly shown. The replacement of lactobacilli with predominantly anaerobic microorganisms (Ureaplasma, Mycoplasma, Gardnerella vaginalis, Prevotella, Peptostreptococcus spp. and Bacteroides spp.), characteristic of bacterial vaginosis, is extremely often detected in patients with CNC. Of particular importance from the point of view of clarifying the pathophysiological mechanisms of development and the development of new diagnostic and prognostic markers, as well as the personalization of CNC therapy, is the study of the cytokine status. Cervicitis and other inflammatory diseases of the lower genital tract are characterized by an increase in the expression of pro-inflammatory cytokines with simultaneous inhibition of the formation of anti-inflammatory cytokines. Significant multidirectional changes in the balance of pro- and anti-inflammatory cytokines were revealed in active and chronic sluggish cervicitis. It should be noted that, despite the variety of proposed approaches to CNC therapy, this problem is still far from being solved to date. One of the promising directions is the personalization of CNC therapy based on molecular genetic markers (polymorphisms of cytokine genes, Toll-like receptors, genes of the detoxification system). The use of such a personalized approach can significantly increase the effectiveness of CNC treatment and reduce the risk of disease recurrence.
The place of virome in women’s reproductive health
Authors: Karakhalis L. Yu. , Kononenko T. S. , Zhigalenko A. R. 
Published: August 2022

Introduction. The vaginal ecosystem is rich in bacteria, the simplest, fungi as well as viruses that are now introduced by the concept of virome. The lack of knowledge of the role of the virome, especially its impact on reproductive and sexual health, aims to study scientific literature on this issue.The purpose of this review is to provide up-to-date data on vaginal virome, its relationship with vaginal microbiota and outcomes of pregnancy, and its impact on reproductive and sexual health.Material and methods. An information search was carried out using Internet resources (PubMed, Web of Science, eLibrary.ru); literature sources for period 2016–2021 were analyzed.Results. The analysis of the scientific data demonstrated the importance of studying the vaginal virome, its role in the development of gynecological and obstetric pathologies the relationship of vaginal viruses with microbiota and immune system of the host organism. And any imbalance of this relationship can contribute to adverse reproductive outcomes, including the infertility.Conclusion. The growing interest in the investigation of vaginal virome requires standardization of laboratory protocols and technologies, including the identification of RNA viruses. However, there are methodological and analytical restrictions on the vaginal virome research. It is suggested that vaginal virome is the missing link between the bacteria of the female genital tract with protective properties of the mucous membranes and adverse reproductive outcomes. In this regard, future studies that assess vaginal virome in the balance between disease and health are very promising.
Sleep disorders, cardiovascular symptoms and body weight dynamics in women with post-COVID-19 syndrome
Authors: Sergeeva V. A. , Lipatova T. E. 
Published: August 2022

Introduction. The COVID-19 pandemic has become a global health problem worldwide. The consequences of the new coronavirus infection continue to be studied. Cardiovascular symptoms and sleep disorders are among the dominant complaints in postCOVID-19 syndrome in women.Aim. To assess sleep disorders, cardiovascular symptoms, body weight dynamics and their statistical relationships in women with post-COVID-19 syndrome.Materials and methods. Using a voluntary anonymous questionnaire, we assessed cardiovascular symptoms, body weight dynamics and sleep disorders in 253 women of different age groups who had COVID-19 at least 12 weeks ago. The severity of dyspnea was assessed using the mMRC (Modified Medical Research Council) scale. Resting heart rate was measured. Statistical processing of the obtained data was carried out using the StatPlus 2009 Professional program.Results and discussion. Among the manifestations of the cardiovascular system in post-COVID-19 syndrome in women of different age groups, palpitations, shortness of breath, and increased blood pressure predominate. There is a statistical pattern in the increased prevalence of rises in blood pressure in post-COVID-19 syndrome among women, depending on age. A variety of sleep disorders occur in all age groups of women, most often in the group of older women. Statistical relationships between sleep disorders and increased blood pressure, severity of dyspnea, palpitations in post-COVID-19 syndrome in women of different age groups were revealed. Severe dyspnea in post-COVID-19 syndrome was frequent noticed in older women. Weight loss in women with post-COVID-19 syndrome is associated with sleep disorders.Conclusions. Cardiovascular symptoms and sleep disorders in post-COVID-19 syndrome in women of different age groups are closely interrelated. The management of patients in post-COVID-19 syndrome should be carried out taking into account the diversity and interaction of various clinical manifestations. Correction of the identified violations should be comprehensive, based on an interdisciplinary approach of various specialists.
Рrognostic value of proadrenomedullin in patients with COVID-19
Authors: Astapovskii A. A. , Drozdov V. N. , Shikh E. V. , Lazareva N. B. , Serebrova S. Yu. 
Published: August 2022

Introduction. In the context of a pandemic, it is necessary to quickly and accurately stratify patients into groups based on the severity of their condition and prognostic risk. For these purposes, some available biomarkers, such as proadrenomedullin, can be used. Objective. To determine the prognostic value of regional mean proadrenomedullin (pro-ADM) in comparison with routine clinical and laboratory parameters in patients with a new coronavirus infection COVID-19. Materials and methods. The study included 140 patients who were hospitalized with a diagnosis of community-acquired pneumonia on the background of COVID-19. The level of pro-ADM was determined on the first and third days of hospitalization by ELISA. In accordance with the outcome of the disease, patients were divided into two groups: those discharged with recovery or improvement (n = 110, 78, 6%) and those who died during their stay in the hospital (n = 30, 21, 4%). Results. Pro-ADM had the highest prognostic value as a predictor of adverse outcome on day 1 AUC ROC 0.72 95% CI (0.57–0.84) sensitivity 79.2%, specificity 62.9% and on day 3 AUC ROC 0.98 95% CI (0.86–1.0) sensitivity 100%, specificity 95.6%. ROC analysis results for C-reactive protein AUC ROC 0.55 95% CI (0.41–0.77), sensitivity 73.3%, specificity 45.6%; procalcitonin AUC ROC 0.62 95% CI (0.49–0.73), sensitivity 80%, specificity 48.2%. The relative risk of a poor outcome for a proADM level > 500 pmol/L is 2.3 95% CI (1.23–4.32), and for a proADM level > 700 it is 8.5 95% CI (4.83–14.94) p < 0.001. Conclusions. Compared to C-reactive protein and procalcitonin, regional mean proadrenomedullin has the highest predictive value as a predictor of death in patients with COVID-19.
School hearing screening: international experience and recommendations
Authors: Chibisova S. S. , Alsharjabi E. , Zyuzin A. S. , Tsigankova E. R. , Popadyuk P. I. , Tavartkiladze G. A. , Kirichenko I. M. 
Published: August 2022

Permanent childhood hearing loss is crucial for speech development and restricts learning abilities. Universal newborn hearing screening programs are well established to detect congenital hearing loss and address the need of hearing-impaired babies. Progressive or acquired permanent hearing loss can manifest later due to genetic causes, intrauterine or postnatal infections, middle ear diseases and excessive exposure to noise when listening the personal audio devices. The hearing loss prevalence in the population of 9 year-olds three times higher compared with newborns. School hearing screening is a part of hearing across the lifespan conception. The article presents international experience and recommendations for the organization of school hearing screening programs. A school-entry hearing test is mandatory, other grades might be screened also. The basic method is pure tone audiometry at frequencies of 500, 1 000, 2 000, 4 000 Hz at 20 dB. Otoscopy and tympanometry can be performed also, while whisper voice speech test is of low sensitivity. The main hearing screening issue is low follow-up of referrals to ascertain audiological assessment. Modern approaches to the prevention of hearing loss in schoolchildren and management of hearing impairements are described. Planning of hearing screening programs requires sufficient human and logistical resources, monitoring of results and quality improvement, all stakeholders engagement.
Do Internal Control Weaknesses Affect Firms’ Demand for Accounting Skills? Evidence from U.S. Job Postings
Authors: Gao Janet , Merkley Kenneth J. , Pacelli Joseph , Schroeder Joseph H. 
Published: August 2022

ABSTRACT
In this study, we examine whether firms respond to internal control weaknesses (ICWs) by requiring accounting-specific skills when hiring rank-and-file employees. Using unique data containing an extensive collection of job postings, we document significant increases in firms’ job postings that list accounting skills after the disclosure of an ICW. This effect is more pronounced for firms with better financial resources and when ICWs are more severe or personnel-related. In addition, our results extend to employees that are not specifically designated as accountants, suggesting a broader role for rank-and-file employees in influencing internal control quality. Finally, we find that increases in job postings with accounting skill requirements are associated with improvements in internal controls and a higher likelihood of ICW remediation. Overall, our findings shed new light on how firms respond to ineffective internal controls by increasing their emphasis on accounting skills in their workforce.
Data Availability: Data are publicly available from the sources identified in the text.
JEL Classifications: G30; J23; M41; M42.
Perbedaan Kemampuan Bersosialisasi Anak yang Mengalami Kecanduan Gadget dengan yang Tidak
Authors: Efastri Sean Marta , Lhaura Lucky , Islami Chitra Charisma 
Published: August 2022

Fenomena di lapangan ditemukan permasalahan pada kemampuan bersosialisasi yang tampak masih ada anak yang tidak mau di tinggalkan oleh orang tuanya ketika akan memasuki kelas untuk belajar, dan orang tua memberikan Gadget untuk dibawa anak ke sekolah, sebagian besar anak menunjukkan sikap tidak mau bermain dengan teman yang baru dikenalnya dan cenderung lebih menyendiri pada jam istirahat dengan menggunakan Gadget. Metodologi yang digunakan dalam penelitian ini adalah dengan jenis penelitian kuantitatif yang bersifat deskriptif komparatif. Perbedaan kemampuan bersosialisasi anak usia 5-6 tahun yang mengalami kecanduan dengan yang tidak terhadap gadget di PAUD Se-Kecamatan Bukit Raya di tunjukan dari hasil uji t menunjukan t-hitung (7.416) ttabel (2.00) dan nilai signifikansi (0,000) α (0,05) artinya Ha diterima Ho ditolak. Adapuan besarnya perbedaan antara anak yang kecanduan dengan yang tidak terhadap gadget yakni mencapai 6.83%.