bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quality‐of‐life evaluations in children and adolescents with Ewing sarcoma treated with pencil‐beam‐scanning proton therapy
Authors: Weber Damien C. , Beer Jürgen , Kliebsch Ulrike L. , Teske Carmen , Baust Katja , Walser Marc , Pica Alessia , Bachtiary Barbara , Timmermann Beate , Calaminus Gabriele 
Published: September 2022

AbstractBackgroundWith improved survival rates for children with cancer, quality‐of‐life (QoL) issues have increasingly become the focus of attention. We report the QoL of children with Ewing sarcoma (EWS) treated with pencil‐beam‐scanning proton therapy (PT).MethodsA PEDQOL (QoL questionnaire for children 4–18 years) self/proxy questionnaire was used to prospectively assess the QoL of 23 children <18 years with EWS treated with PT. This questionnaire evaluates eight different domains. Children (self‐rating) and parents (proxy‐rating) filled out the questionnaire at the start of PT (E1), 2 months after treatment (E2), and thereafter once yearly (E≥3).ResultsCompared with healthy controls, parents rated the QoL of their children at E1 significantly worse in all but two (cognition and social functioning‐family) domains. At E4, significant differences between the two groups only remained in three of eight domains. At E1, children self‐rated their QoL significantly worse in the domain Physical functioning (p = .004) and significantly better in the domain Body image (p = .044) compared to healthy controls, whereas no significant differences were observed at E4. For the longitudinal comparison E1 versus E4, according to parents, Emotional functioning, Cognition and Social functioning‐peers were slightly decreased 2 years after PT. The children rated Emotional functioning and Body image poorly 2 years after PT.ConclusionsChildren with EWS usually recovered seemingly well to normal QoL levels 2 years after the end of PT. They tended to rate their QoL substantially higher than their parents. However, in the longitudinal analysis at 2 years, children rated their Emotional functioning and Body image scores poorly.
Repair of reinforced concrete bridge columns subjected to chloride‐induced corrosion with ultra‐high performance fiber reinforced concrete
Authors: Pelle Angelo , Briseghella Bruno , Fiorentino Gabriele , Giaccu Gian Felice , Lavorato Davide , Quaranta Giuseppe , Rasulo Alessandro , Nuti Camillo 
Published: September 2022

AbstractThe rehabilitation of reinforced concrete (RC) bridge columns subjected to chloride‐induced corrosion is addressed in the present paper. The proposed strategy is based on the replacement of the original external layer made of normal‐strength concrete (NSC) with ultra‐high performance fiber reinforced concrete (UHPFRC), and it additionally involves the substitution of the existing corroded longitudinal reinforcement with new machined steel rebars. This repair technique aims at restoring strength, stiffness, and ductility of the original column in a short time without altering its cross‐section dimensions. Because of the high compactness of the UHPFRC, it also serves at improving its durability. The main contribution of the present work is a numerical investigation carried out in order to identify how the design decisions about the repair strategy influence the behavior of the restored column. The parametric investigation reveals that the length of the zone in which NSC is replaced by UHPFRC as well as the machined index (i.e., ratio between turned and original rebar cross‐section area) must be properly selected to make the intervention effective. Numerical results also highlight that the main design issue to deal with is the relocation of the plastic hinge from the repaired zone towards the weak unrepaired part of the column. Practical design recommendations are finally formulated.
Intravenous regional antibiotic perfusion as an adjunctive therapy to treat osteomyelitis in a common snapping turtle (Chelydra serpentina)
Authors: Cherukuri Aswini , Scott‐Cruz Sarah , Lewbart Gregory , Petrovitch Nicholas , Ozawa Sarah 
Published: September 2022

AbstractA wild, adult, male common snapping turtle (Chelydra serpentina) presented to North Carolina State University's Turtle Rescue Team (TRT) with injuries consistent with vehicular trauma. Injuries included head trauma with an associated superficial lesion of the head and an overpronated left forelimb with a necrotic wound on the palmar surface. Osteomyelitis localised to the left forelimb was considered the primary differential based on radiographic findings and clinical signs. To treat osteomyelitis, regional antibiotic limb perfusions were conducted approximately once per week. After conducting seven total regional antibiotic limb perfusions, the patient's ambulation and mentation improved significantly and there was no progression of osteomyelitis on repeated radiographs. The patient was released to the wild after 5 months under human care. This case report demonstrates the potential use of regional antibiotic limb perfusion as an adjunctive therapy for osteomyelitis in chelonians.
An Analysis of the Security and Privacy Issues of the Neovote Online Voting System
Authors: Blanchard Enka , Gallais Antoine , Leblond Emmanuel , Sidhoum-Rahal Djohar , Walter Juliette 
Published: September 2022

AbstractThis article provides the first security and privacy analysis of the Neovote voting system, which was used for three of the five primaries in the French 2022 presidential election. We show that the demands of transparency, verifiability and security set by French governmental organisations were not met, and propose multiple attacks against the system targeting both the breach of voters’ privacy and the manipulation of the tally. We also show how inconsistencies in the verification system allow the publication of erroneous tallies and document how this arrived in practice during one of the primary elections.
Review Your Choices: When Confirmation Pages Break Ballot Secrecy in Online Elections
Authors: Brunet James , Pananos Athanasios Demetri , Essex Aleksander 
Published: September 2022

AbstractOnline voting systems typically display a confirmation screen allowing voters to confirm their selections before casting. This paper considers whether a network-based observer can extract information about voter selections from the length of the exchanged network data.We conducted a detailed analysis of the Simply Voting implementation, which had randomly varying lengths of exchanged data due to dynamic page content and gzip compression. We demonstrated that we could correctly guess a voter’s selection with accuracy values ranging up to 100% in some instances. Even on more complex ballots, we generally could still rule out some combinations of candidates. We conducted a coordinated disclosure with the vendor and worked with them to roll out a mitigation.To their credit, this discovery (and therefore its fix) was made possible by their willingness to provide a publicly accessible demo, which, as we will show, remains a rarity in the industry.
Sensitivity to dark sector scales from gravitational wave signatures
Authors: Dent James B. , Dutta Bhaskar , Ghosh Sumit , Kumar Jason , Runburg Jack 
Published: September 2022

Abstract
We consider gravitational sound wave signals produced by a first-order phase transition in a theory with a generic renormalizable thermal effective potential of power law form. We find the frequency and amplitude of the gravitational wave signal can be related in a straightforward manner to the parameters of the thermal effective potential. This leads to a general conclusion; if the mass of the dark Higgs is less than 1% of the dark Higgs vacuum expectation value, then the gravitational wave signal will be unobservable at all upcoming and planned gravitational wave observatories. Although the understanding of gravitational wave production at cosmological phase transitions is still evolving, we expect this result to be robust.
Two-body decays in deformed relativity
Authors: Lobo Iarley P. , Pfeifer Christian , Morais Pedro H. , Batista Rafael Alves , Bezerra Valdir B. 
Published: September 2022

Abstract
Deformed relativistic kinematics is a framework which captures effects, that are expected from particles and fields propagating on a quantum spacetime, effectively. They are formulated in terms of a modified dispersion relation and a modified momentum conservation equation. In this work we use Finsler geometry to formulate deformed relativistic kinematics in terms of particle velocities. The relation between the Finsler geometric velocity dependent formulation and the original momentum dependent formulation allows us to construct deformed Lorentz transformations between arbitrary frames. Moreover, we find the corresponding compatible momentum conservation equation to first order in the Planck scale deformation of special relativity based on the κ-Poincaré algebra in the bicrossproduct basis. We find that the deformed Lorentz transformations, as well as the deformed time dilation factor, contain terms that scale with the energy of the particle under consideration to the fourth power. We derive how the distributions of decay products are affected when the deformed relativity principle is satisfied and find, for the case of a pion decaying into a neutrino and a muon, that the ratio of expected neutrinos to muons with a certain energy is just slightly modified when compared to the predictions based on special relativity. We also discuss the phenomenological consequences of this framework for cosmic-ray showers in the atmosphere.
Analytic Computation of three-point energy correlator in QCD
Authors: Yang Tong-Zhi , Zhang Xiaoyuan 
Published: September 2022

Abstract
The energy correlator measures the energy deposited in multiple detectors as a function of the angles among them. In this paper, an analytic formula is given for the three-point energy correlator with full angle dependence at leading order in electron-positron annihilation. This is the first analytic computation of trijet event shape observables in QCD, which provides valuable data for phenomenological studies. The result is computed with direct integration, where appropriate parameterizations of both phase space and kinematic space are adopted to simplify the calculation. With full shape dependence, our result provides the expansions in various kinematic regions such as equilateral, triple collinear and squeezed limits, which benefit studies on both factorization and large logarithm resummation.
Optimisation of convolutional neural network architecture using genetic algorithm for the prediction of adhesively bonded joint strength
Authors: Arhore Edore G. , Yasaee Mehdi , Dayyani Iman 
Published: September 2022

AbstractThe classical method of optimising structures for strength is computationally expensive due to the requirement of performing complex non-linear finite element analysis (FEA). This study aims to optimise an artificial neural network (ANN) architecture to perform the task of predicting the strength of adhesively bonded joints in place of non-linear FEA. A manual multi-objective optimisation was performed to find a suitable ANN architecture design space. Then a genetic algorithm optimisation of the reduced design space was conducted to find an optimum ANN architecture. The generated optimum ANN architecture predicts efficiently the strength of adhesively bonded joints to a high degree of accuracy in comparison with the legacy method using FEA with a 93% savings in computational cost.
The VMO-Teichmüller space and the variant of Beurling–Ahlfors extension by heat kernel
Authors: Wei Huaying , Matsuzaki Katsuhiko 
Published: September 2022

AbstractWe give a real-analytic section for the Teichmüller projection onto the VMO-Teichmüller space by using the variant of Beurling–Ahlfors extension by heat kernel introduced by Fefferman et al. (Ann Math 134:65–124, 1991). Based on this result, we prove that the VMO-Teichmüller space can be endowed with a real Banach manifold structure that is real-analytically equivalent to its complex Banach manifold structure. We also obtain that the VMO-Teichmüller space admits a real-analytic contraction mapping.
Regional myocardial perfusion imaging in predicting vessel-related outcome: interplay between the perfusion results and angiographic findings
Authors: Mannarino Teresa , D’Antonio Adriana , Assante Roberta , Zampella Emilia , Gaudieri Valeria , Buongiorno Pietro , Cantoni Valeria , Green Roberta , Nappi Carmela , Criscuolo Emanuele , Bologna Roberto , Petretta Mario , Slomka Piotr , Cuocolo Alberto , Acampa Wanda 
Published: September 2022

Abstract
Background
Despite myocardial perfusion imaging (MPI) by cadmium-zinc-telluride (CZT) single-photon emission computed tomography (SPECT) camera is largely used in the diagnosis and risk stratification of patients with suspected or known coronary artery disease (CAD), no data are available on the prognostic value of a regional MPI evaluation. We evaluated the prognostic value of regional MPI by the CZT camera in predicting clinical outcomes at the vessel level in patients with available angiographic data.

Methods and results
Five hundred and forty-one subjects with suspected or known CAD referred to 99mTc-sestamibi gated CZT-SPECT cardiac imaging and with available angiographic data were studied. Both regional total perfusion deficit (TPD) and ischemic TPD (ITPD) were calculated separately for each vascular territory (left anterior descending, left circumflex, and right coronary artery). The outcome end points were cardiac death, target vessel-related myocardial infarction, or late coronary revascularization. The prevalence of CAD ≥ 50%, regional stress TPD, and regional ITPD was significantly higher in vessels with events as compared to those without (both P < 0.001). The receiver operating characteristics area under the curve for regional ITPD for the identification of vessel-related events was 0.81 (95% confidence interval 0.75–0.86). An ITPD value of 2.0% provided the best trade-off for identifying the vessel-related event. At multivariable analysis, both CAD ≥ 50% and ITPD ≥ 2.0% resulted in independent predictors of events.

Conclusions
Regional myocardial perfusion assessed by the CZT camera demonstrated good reliability in predicting vessel-related events in patients with suspected or known CAD.
Revisiting trends in morphology of antennal sensilla in scarabaeoid beetles
Authors: Pacheco Thaynara L. , Bohacz Claudia , Ballerio Alberto , Schoolmeesters Paul , Ahrens Dirk 
Published: September 2022

AbstractPhytophagous scarab beetles associated with angiosperms have characteristically enlarged lamellate antennae and exhibit a striking morphological variation of sensilla. In this study, we compared the morphology of antennal surface of 62 species Scarabaeoidea using SEM microscopy, particularly also in light of their evolution in association with angiosperms. We investigated the correlation of antennal sensilla morphology, i.e., their structure and distribution, with species diversity and lineage diversification rates. A high diversity of sensilla was observed but also multiple transitional forms, even on the same antennomere. We interpreted this as evidence for a high evolutionary plasticity. We recognized clear patterns of convergence and repeated evolution of certain types of placoid sensilla. One main tendency found in the phytophagous Pleurostict chafers was a shift from sensilla trichodea to placoid-like sensilla, apparently also enhanced by the increase of the lamellate antennal surface, either by size or number of the lamellae. This trend occurred not only in the Pleurosticts, but also in Glaphyridae, a second angiosperm-associated lineage of Scarabaeoidea. However, our results suggest no direct relation between species diversity or the rate of diversification and general sensilla morphology, i.e., the origin of placoid sensilla. This could be explained not only by species-poor lineages also possessing placoid sensilla but also by otherwise successful and species rich groups having sensilla trichodea (e.g., dung beetles). Results further reveal the need to refine current phylogenetic hypotheses by more comprehensive taxon sampling and to expand the molecular characterization of pheromones and odor binding proteins to better understand the role of chemical communication in scarab diversification.
Improvement rates, adverse events and predictors of clinical outcome following surgery for degenerative cervical myelopathy
Authors: de Dios Eddie , Laesser Mats , Björkman-Burtscher Isabella M. , Lindhagen Lars , MacDowall Anna 
Published: September 2022

Abstract
Purpose
To investigate improvement rates, adverse events and predictors of clinical outcome after laminectomy alone (LAM) or laminectomy with instrumented fusion (LAM + F) for degenerative cervical myelopathy (DCM).

Methods
This is a post hoc analysis of a previously published DCM cohort. Improvement rates for European myelopathy score (EMS) and Neck Disability Index (NDI) at 2- and 5-year follow-ups and adverse events are presented descriptively for available cases. Predictor endpoints were EMS and NDI scores at follow-ups, surgeon- and patient-reported complications, and reoperation-free interval. For predictors, univariate and multivariable models were fitted to imputed data.

Results
Mean age of patients (LAM n = 412; LAM + F n = 305) was 68 years, and 37.4% were women. LAM + F patients had more severe spondylolisthesis and less severe kyphosis at baseline, more surgeon-reported complications, more patient-reported complications, and more reoperations (p ≤ 0.05). After imputation, the overall EMS improvement rate was 43.8% at 2 years and 36.3% at 5 years. At follow-ups, worse EMS scores were independent predictors of worse EMS outcomes and older age and worse NDI scores were independent predictors of worse NDI outcomes. LAM + F was associated with more surgeon-reported complications (ratio 1.81; 95% CI 1.17–2.80; p = 0.008). More operated levels were associated with more patient-reported complications (ratio 1.12; 95% CI 1.02–1.22; p = 0.012) and a shorter reoperation-free interval (hazard ratio 1.30; 95% CI 1.08–1.58; p = 0.046).

Conclusions
These findings suggest that surgical intervention at an earlier myelopathy stage might be beneficial and that less invasive procedures are preferable in this patient population.
Comparison of EASYDO ACTIVATOR, passive ultrasonic, and needle irrigation techniques on the treatment of apical periodontitis: a study in rats
Authors: Ye Qin , Feng Yao , Zhao Ya-Qiong , Tan Li , Hu Jing , Zhang Shao-Hui , Zhao Jie , Zhou Ying-Hui , Guo Yue , Feng Yun-Zhi 
Published: September 2022

Abstract
Objectives
To evaluate the long-term therapeutic effect of EASYDO ACTIVATOR, passive ultrasonic irrigation, and needle irrigation in experimental apical periodontitis in rats.

Materials and methods
Sprague-Dawley male rats were used to produce periapical lesions. The pulp chambers of the bilaterally first mandibular molars were exposed and left open for 21 days. The rats were divided into four groups according to different irrigation protocols. Seven days after irrigation, the mandibles were removed for micro-CT, histological, and immunohistochemical analysis. Serum levels of tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) were assessed by enzyme-linked immunosorbent assays (ELISA). Statistical data were analyzed by one-way analysis of variance (ANOVA) with LSD tests.

Results
The passive ultrasonic irrigation and EASYDO ACTIVATOR groups had the smallest apical lesions compared to the other groups (P < 0.05), while the needle irrigation group had smaller lesions than the control group (P < 0.05). The EASYDO ACTIVATOR group had less inflammation infiltration compared to the control and needle irrigation groups (P < 0.05). The control and needle irrigation groups had more TNF-α expression compared to the passive ultrasonic irrigation and EASYDO ACTIVATOR groups (P < 0.05). The lowest IL-6 expression was observed in the EASYDO ACTIVATOR group. The EASYDO ACTIVATOR group had the lowest serum level of TNF-α than other groups (P < 0.05). IL-6 expression was significantly lower in the EASYDO ACTIVATOR group in comparison with the control and needle irrigation groups (P < 0.05).

Conclusions
EASYDO ACTIVATOR can significantly reduce the apical lesions and decrease the inflammatory response around the periapical area.

Clinical relevance
EASYDO ACTIVATOR is recommended for clinical application.
Resource allocations with guaranteed awards in claims problems
Authors: Giménez-Gómez José-Manuel , Peris Josep E. , Solís-Baltodano María-José 
Published: September 2022

AbstractThe notion of lower bound on awards has been introduced in the literature to analyze the establishment of guarantees that ensure a minimum award to each agent involved in situations of conflicting claims, such as the rationing of a resource or the distribution of the assets of a bankrupt firm. Indeed, this concept has a core role in many approaches related to the problem of fair allocation (Thomson in Math Soc Sci 74:41–59, 2015) and a range of such lower bounds have been proposed: the minimal right (Curiel et al. in Z Oper Res 31:A143–A159, 1987), the fair bound (Moulin in Handb Soc Choice Welf 1:289–357, 2002), securement (Moreno-Ternero and Villar in Math Soc Sci 47(2):245–257, 2004) and the $$\min $$
min
bound (Dominguez in mimeo, 2006). In this context, the key contribution of the current paper is to show that there is a correspondence between lower bounds and rules; i.e., associated to each particular lower bound, we find a specific way of distributing the resources. In doing so, we provide new characterizations for two well known rules, the constrained equal awards and Ibn Ezra’s rules. A dual analysis, by using upper bounds on awards will provide characterizations of the dual of the previously mentioned rules: the constrained equal losses rule and the dual of Ibn Ezra’s rule.
Unveiling hydrogen evolution dependence on KOH concentration for polycrystalline and nanostructured nickel-based catalysts
Authors: Faid Alaa Y. , Foroughi Faranak , Sunde Svein , Pollet Bruno 
Published: September 2022

AbstractNickel-based hydrogen evolution reaction (HER) electrodes have been widely used in alkaline and anion exchange membrane water electrolysis. Therefore, understanding the activity dependence on the KOH concentration (pH) of alkaline electrolytes is essential for designing durable and active HER catalysts. In this work, the HER activity and kinetics of polycrystalline and nanostructured nickel-based catalysts are evaluated in various pH and KOH concentrations. The results for nanostructured NiMo catalyst indicate that both electrochemical active surface area and reaction order have a promoting region under various pH’s and KOH concentrations (0.01–1.0 M, pH 12–14) accompanied by better HER activity (a lower overpotential for achieving − 10 mA cm−2) and Tafel slope decreases from around 180 mV dec−1 to 60 mV dec−1 in the same pH and KOH concentration range. The change in the Tafel slope indicates that the HER rate-determining step for HER at NiMo/C changes with pH and KOH concentration. The polycrystalline Ni displays different behaviours where a promoting (0.01–0.10 M, pH 12–13), stabilizing (0.1–1.0 M, pH 13–14), and an inhibiting region (2 M, pH > 14) are present. However, Tafel slopes of around 120 mV/dec are obtained for polycrystalline Ni at all KOH concentrations. The HER characteristics are inhibited at 2.0 M KOH for both catalysts due to slower OH* transport kinetics. The results confirmed the importance of tuning catalyst-pH/KOH concentration for better HER activity and kinetics.
Graphical abstract