bluuebunny/crossref_metadata_2025_split huggingface dataset:
Instantaneous microwave frequency measurement with single branch detection based on the birefringence effect
Authors: Zhu Wei , Li Jing , Pei Li , Ning Tigang , Zheng Jingjing , Wang Jianshuai 
Published: June 2022

Instantaneous frequency measurement (IFM) with single branch detection based on the birefringence effect is proposed and experimentally demonstrated. The unknown microwave frequencies are modulated to pump a length of polarization maintaining fiber. Due to the fiber birefringence effect, the input light signal is decomposed into two orthogonal-polarization signals with a relative time delay. After detection, an amplitude comparison function (ACF) is obtained by comparing the alternating-current and direct-current powers. Therefore, no multipath detection is needed so that the electrical variations in the photonic link can be cancelled out in ACF. A theoretical analysis is given to illustrate the mechanism of the proposed IFM system. The disturbances are investigated and discussed in simulation. A proof-of-concept experiment is carried out for verification with a result of

±

0.2

G
H
z

over 2.2–5.2 GHz.
Mid-infrared broadband optical frequency comb generated in MgF2 resonators
Authors: Wu Wei , Sun Qibing , Wang Yi , Yang Yu , Ming Xianshun , Shi Lei , Wang Keyi , Zhao Wei , Wang Leiran 
Published: June 2022

Microresonator-based optical frequency combs are broadband light sources consisting of equally spaced and coherent narrow lines, which are extremely promising for applications in molecular spectroscopy and sensing in the mid-infrared (MIR) spectral region. There are still great challenges in exploring how to improve materials for microresonator fabrication, extend spectral bandwidth of parametric combs, and realize fully stabilized soliton MIR frequency combs. Here, we present an effective scheme for broadband MIR optical frequency comb generation in a

MgF

2

crystalline microresonator pumped by the quantum cascade laser. The spectral evolution dynamics of the MIR Kerr frequency comb is numerically investigated, revealing the formation mechanism of the microresonator soliton comb via scanning the pump-resonance detuning. We also experimentally implement the modulation instability state MIR frequency comb generation in

MgF

2

resonators covering from 3380 nm to 7760 nm. This work proceeds microresonator-based comb technology toward a miniaturization MIR spectroscopic device that provides potential opportunities in many fields such as fundamental physics and metrology.
Values of the Metaverse: Hybride Arbeit in virtuellen Begegnungsräumen
Authors: Kammler Paula , Gravemeier Laura Sophie , Göritz Lorena , Kammler Friedemann , Gembarski Paul Christoph 
Published: June 2022

ZusammenfassungSpätestens seit Beginn der Corona-Pandemie ist eine Vielzahl von Unternehmen aufgrund von Social-Distancing-Maßnahmen und neuen Mitarbeiteranforderungen mit hybrider Arbeit als neuem Status Quo konfrontiert. Während hierin absehbar das Potenzial zur generellen Flexibilisierung von Arbeit liegt, müssen Arbeitgeber veränderte Formen der Zusammenarbeit auch ermöglichen und räumliche Distanzen überbrücken. Hinzu kommt, dass der unerwartete Eintritt der pandemischen Lage oftmals zur ad-hoc-Einführung von Werkzeugen geführt hat, die als „Erste Hilfe“-Lösung grundsätzliche Kommunikation und Kollaboration ermöglichen sollten. Knapp drei Jahre nach Beginn der Pandemie vergleichen wir gemeinsam mit Initiatoren und Nutzern zwei derartige Anwendungsfälle, die die Metaverse-Lösung Gather eingeführt haben. In einer multiperspektivischen Untersuchung fragen wir nach den geplanten und realisierten Mehrwerten und stellen Verbindungen zu den Features der Software her. Aus den Erkenntnissen leiten wir zwei Arten von Handlungsempfehlungen ab. Einerseits, inwiefern Gather ad-hoc als „Erste Hilfe“-Lösung geeignet ist und andererseits, welche Potenziale in der zukünftigen Überarbeitung gehoben werden können, um ein robustes hybrides Arbeitsmodell aufzubauen.
Systematic inference of indirect transcriptional regulation by protein kinases and phosphatases
Authors: Madsen Christian Degnbol , Hein Jotun , Workman Christopher T. 
Published: June 2022

Gene expression is controlled by pathways of regulatory factors often involving the activity of protein kinases on transcription factor proteins. Despite this well established mechanism, the number of well described pathways that include the regulatory role of protein kinases on transcription factors is surprisingly scarce in eukaryotes.
To address this, PhosTF was developed to infer functional regulatory interactions and pathways in both simulated and real biological networks, based on linear cyclic causal models with latent variables. GeneNetWeaverPhos, an extension of GeneNetWeaver, was developed to allow the simulation of perturbations in known networks that included the activity of protein kinases and phosphatases on gene regulation. Over 2000 genome-wide gene expression profiles, where the loss or gain of regulatory genes could be observed to perturb gene regulation, were then used to infer the existence of regulatory interactions, and their mode of regulation in the budding yeast Saccharomyces cerevisiae.
Despite the additional complexity, our inference performed comparably to the best methods that inferred transcription factor regulation assessed in the DREAM4 challenge on similar simulated networks. Inference on integrated genome-scale data sets for yeast identified ∼ 8800 protein kinase/phosphatase-transcription factor interactions and ∼ 6500 interactions among protein kinases and/or phosphatases. Both types of regulatory predictions captured statistically significant numbers of known interactions of their type. Surprisingly, kinases and phosphatases regulated transcription factors by a negative mode or regulation (deactivation) in over 70% of the predictions.
Scabies epidemiology in health care centers for refugees and asylum seekers in Greece
Authors: Louka Christina , Logothetis Emmanouil , Engelman Daniel , Samiotaki-Logotheti Eirini , Pournaras Spyros , Stienstra Ymkje 
Published: June 2022

Background
Scabies is a global health concern disproportionately affecting vulnerable populations such as refugees and asylum seekers. Greece is a main point of entry in Europe for refugees, but epidemiological data on scabies in this population are scarce. We aimed to describe the epidemiology of scabies, including trends over the study period.

Methodology/Principal findings
Data were collected from June, 2016 to July, 2020, using the surveillance system of the Greek National Public Health Organization. Daily reports on scabies and other infectious diseases were submitted by staff at health centers for refugees/asylum seekers. Observed proportional morbidity for scabies was calculated using consultations for scabies as a proportion of total consultations.
There were a total of 13118 scabies cases over the study period. Scabies was the third most frequently observed infectious disease in refugees/asylum seekers population after respiratory infections and gastroenteritis without blood in the stool. The scabies monthly observed proportional morbidity varied between 0.3% (August 2017) to 5.7% (January 2020). Several outbreaks were documented during the study period. The number of cases increased from October 2019 until the end of the study period, with a peak of 1663 cases in January 2020, related to an outbreak at one center. Spearman correlation test between the number of reported scabies cases and time confirmed an increasing trend (ρ = 0.67).

Conclusions/Significance
Scabies is one of the most frequently reported infectious diseases by health care workers in refugee/asylum seekers centers in Greece. Observed proportional morbidity for scabies increased over time and there were several outbreaks. The current surveillance system with daily reports of the new cases effectively detects new cases in an early stage. Public health interventions, including mass drug administration, should be considered to reduce the burden of scabies in refugee/migrant populations.
Identification of sarcopenic obesity in adults undergoing orthopaedic surgery: Relationship between “a body shape index” (ABSI) and fat-free mass. A cross -sectional study
Authors: Tomažič Ana , Žvanut Boštjan , Grbac Lilijana Vouk , Jurdana Mihaela 
Published: June 2022

Background
Sarcopenic obesity is a condition characterised by the coexistence of low muscle mass and function (sarcopenia) and excessive fat mass (obesity). The aim of this study was to determine the prevalence of this condition in patients undergoing orthopaedic surgery by gender and type of orthopaedic surgery. In addition, this study investigated the suitability of a waist circumference-based anthropometric measure, body shape index (ABSI), for predicting sarcopenic obesity and the predictive power of ABSI for fat-free mass index (FFMI), a surrogate marker of lean body mass.

Methods and findings
A cross-sectional study of overweight and obese orthopaedic patients undergoing knee or hip and spine surgery was conducted between October 2019 and March 2020 in Orthopaedic Hospital Valdoltra, Slovenia. General anthropometric parameters body mass index (BMI) and ABSI = (WC/(BMI2/3x height½) as well as body composition data (fat mass FM, fat-free mass FFM, FFMI, and the ratio FM/FFM as an index of sarcopenic obesity) were determined in 120 women (aged 66.5 ± 9.6 years) and 89 men (aged 65.5 ± 7.8 years) with overweight (25 kg/m2 ≤ BMI < 30 kg/m2) and obesity (BMI ≥ 30 kg/m2) by bioelectrical impedance analysis (BIA). Sarcopenic obesity phenotypes based on FM/FFM ratio > 0.80 was present in 15.3% of patients, mainly in female patients undergoing knee surgery. ABSI was significantly associated with age in all women and obese men and with waist circumference (WC) in all patients. ABSI did not correlate with BMI in women and men; however, multiple linear regression analysis showed that BMI independently predicted FFMI (R = 0.83 and 0.70, respectively, p < 0.001) in women and men (β-coefficients: 0.801 and 0.686, respectively) and ABSI in women only (β-coefficient: -0.104). Women with a lower ABSI had a significantly higher FFMI than the group with a higher ABSI.

Conclusions
Sarcopenic obesity was most prevalent in obese women scheduled for knee surgery. In addition, ABSI, independently predicted FFMI in women and represents a significant predictor of sarcopenic obesity.
Netherite
Authors: Burckhardt Sebastian , Chandramouli Badrish , Gillum Chris , Justo David , Kallas Konstantinos , McMahon Connor , Meiklejohn Christopher S. , Zhu Xiangfeng 
Published: June 2022

Serverless is a popular choice for cloud service architects because it can provide scalability and load-based billing with minimal developer effort. Functions-as-a-service (FaaS) are originally stateless, but emerging frameworks add stateful abstractions. For instance, the widely used Durable Functions (DF) allow developers to write advanced serverless applications, including reliable workflows and actors, in a programming language of choice. DF implicitly and continuosly persists the state and progress of applications, which greatly simplifies development, but can create an IOps bottleneck.
To improve efficiency, we introduce Netherite, a novel architecture for executing serverless workflows on an elastic cluster. Netherite groups the numerous application objects into a smaller number of partitions, and pipelines the state persistence of each partition. This improves latency and throughput, as it enables workflow steps to group commit, even if causally dependent. Moreover, Netherite leverages FASTER's hybrid log approach to support larger-than-memory application state, and to enable efficient partition movement between compute hosts.
Our evaluation shows that (a) Netherite achieves lower latency and higher throughput than the original DF engine, by more than an order of magnitude in some cases, and (b) that Netherite has lower latency than some commonly used alternatives, like AWS Step Functions or cloud storage triggers.
DLCR
Authors: Chen Xin , Peng You , Wang Sibo , Yu Jeffrey Xu 
Published: June 2022

Many real-world graphs, e.g., social networks, biological networks, knowledge graphs, naturally come with edge-labels, with different labels representing different relationships between nodes. On such edge-labeled graphs, an important query is thelabel-constrained reachability (LCR)query, where we are given a sources, a targett, a label set ψ, and the goal is to check if there exists any pathPfromstotsuch that labels of edges onPall belong to ψ. Existing indexing schemes for LCR queries still focus on static graphs, despite the fact that many edge-labeled graphs are dynamic in nature.Motivated by the limitations of existing solutions, we present a study on how to effectively maintain the indexing scheme on dynamic graphs. Our proposed approach is based on the state-of-the-art 2-hop index for LCR queries. In this paper, we present efficient algorithms for updating the index structure in response to dynamic edge insertions/deletions and demonstrate the correctness of our update algorithms. Following that, we present that adopting a query-friendly but update-unfriendly indexing scheme results in surprisingly superb query/update efficiency and outperforms those update-friendly ones. We analyze and demonstrate that the query-friendly indexing scheme actually achieves the same time complexity as those of update-friendly ones. Finally, we present the batched update algorithms where the updates may include multiple edge insertions/deletions. Extensive experiments show the effectiveness of the proposed update algorithms, query-friendly indexing scheme, and batched update algorithms.
An accurate but simple method for estimation of the influence of kerr nonlinearity on the far field pattern of LP11 mode in dispersion-shifted and dispersion-flattened fibers
Authors: Roy Kushal , Majumdar Angshuman , Gangopadhyay Sankar 
Published: June 2022

Abstract
In this paper, we have presented the far field pattern in presence and absence of Kerr type nonlinearity for the first higher order mode in Dispersion shifted and dispersion flattened type optical fibers. Our analytical results are based on simple power series expressions for the first higher order (LP11) mode of aforesaid fibers, which have been formulated by Chebyshev formalism. Using the analytical expressions for the linear case, method of iteration is applied in order to predict the concerned propagation parameters in presence of Kerr type nonlinearity. We have taken some typical trapezoidal index, step W and Parabolic W fibers for our study. Our results for the far field pattern have been shown to be in excellent agreement with the exact numerical results computed by rigorous finite element technique. The simplicity and accuracy of our formalism will prove helpful to the designers for setting up of efficient low dispersion optical link.
Multiple-scale analysis of the parametric-driven sine-Gordon equation with phase shifts
Authors: Munir Taj , ur Rahman Rana Atta , Raza Ali , Malik Muhammad Yousaf , Khan Ilyas , Ashour Ahmed , Mousa Abd Allah A. , Alqahtani Ali Saeed 
Published: June 2022

Abstract
In this article, we model the current and voltage across the weak link between two superconductors. This gives us a nonhomogeneous, nonlinear parametric-driven sine-Gordon equation with phase shifts. This model equation cannot be solved directly but can be approximated. For the approximations, we use two methods, and analytic perturbation method and the numerical approximation method known as the Runge–Kutta method. For the analytic method, we construct a perturbation expansion method with multiple-scale expansion. We discuss the parametric-driven in the sine-Gordon equation with phase shifts for the 0–π–0 junction. Further, we also describe the breathing modes for various order of perturbation. At the end, we compare the solutions obtained via perturbation and numerical methods of parametric-driven sine-Gordon equation with phase shifts. Finally, we concluded that the modes of the breathing decay to a constant in both cases. Also we found a good agreement between both approximate methods.
A múzeum, mint vonzerő az egyetemista korosztály szemszögéből
Authors: Schultz Éva , Szalók Csilla 
Published: June 2022

A TANULMÁNY CÉLJA
A tanulmány célja az múzeumok vonzerejének vizsgálata az egyetemisták körében. A hazai kultúrafogyasztással foglalkozó kutatások alapján a fiatal felnőtt korosztály inkább kimaradó múzeumlátogatói szegmens. A múzeum identitásformáló kultúraközvetítő intézmény, közösségi tér és gyakran turisztikai vonzerő is. Kutatásunk főként ez utóbbi szerep hatásán keresztül vizsgálja a fiatal felnőtt célcsoport az intézménnyel kapcsolatos attitűdjét, látogatói preferenciáit, megszólításának lehetőségeit.
ALKALMAZOTT MÓDSZERTAN
A primer vizsgálat módszereként a BGE KVIK hallgatói körében végzett, feltáró jellegű kvantitatív kutatás szolgált. Kutatási kérdéseink a következők: milyen múzeumi élmény- és elvárásmintázatok fogalmazhatók meg a Z generáció e szegmensének szemszögéből? Mi jellemzi attitűdjüket a múzeumok, mint lokális kulturális intézmények és mint turisztikai attrakciók iránt?
LEGFONTOSABB EREDMÉNYEK
A megkérdezettek mobilis kultúrafogyasztók, a lakóhelyen kívüli intézményi kultúrafogyasztásukban kiemelkedő a múzeum szerepe. A múzeummal kapcsolatos elvárásaik a hagyományos funkciók és a modern interpretációs technológia ötvözeteként jellemezhetők. Az utazások során jellemzőbb a múzeumlátogatás, mint egyébként, a fő motiváció a felfedezés vágya és a híres látnivalók élményígérete. A múzeumi élmény vonatkozásában hangsúlyos a rekreatív, szórakoztató jelleg és az aktív részvétel igénye.
GYAKORLATI JAVASLATOK
Eredményeink segíthetik a hazai múzeumokat az egyetemista korosztály igényeinek, élmény-elvárásainak jobb megismerésében, ezáltal eredményesebb megszólításában és szolgáltatásaik célcsoport-specifikus bővítésében. Ösztönzőleg hathatnak a hazai múzeumok poszt-COVID turizmusban vizionált helyére, hiszen erősödik a hazai, biztonságos, autentikus élmények iránti érdeklődés, aminek a múzeumok kiváló terepei.
Self-Monitoring of Damage Evolution in Asphalt Concrete Based on Electrical Resistance Change Method
Authors: Dong Zejiao , Ullah Shafi , Zhou Tao , Yang Chen , Luan Hai , Khan Rawid 
Published: June 2022

Abstract
Asphalt pavements expose early damage during their service life. The early damage grows internally until it accumulates and transforms into macro-damage that leads to structural failure. To promote real-time monitoring of internal damage evolution in asphalt pavements, this study proposes an electrical resistance change (ERC) method that exploits the piezoresistive properties of conductive asphalt concrete as a nondestructive testing technique capable of detecting microstructural defects. For this purpose, the traditional asphalt mixtures were first made electrically conductive by adding carbon fibers and iron tailing aggregates as conductive aggregates to satisfy the piezoresistivity requirements. Secondly, piezoresistivity experiments were performed by applying cyclic tensile force in fatigue and progressively increasing mode. The self-monitoring ability of damage evolution was assessed based on the correlation between the fractional change in electrical resistance (FCR), displacement, and damage degree for each mode of the force application. It was observed that under fatigue mode, the FCR and displacement increase upon loading and decrease reversibly upon unloading in each cycle. Compared with the displacement, the FCR exhibits partial reversibility upon unloading, indicating damage initiation in each cycle. The damage grows with the number of loading cycles until it accumulates in the elastic regime and gradually affects the load-carrying capacity of the mixture. Under a progressively increasing mode, the mixture exhibits a good correlation between the FCR and force in the elastic regime, ensuring real-time monitoring of internal micro-damage. However, the FCR develops a nonlinear correlation with the force in the inelastic regime that reflects damage to the conductive network and eventually structural failure. In summary, the ERC method provides real-time monitoring of microstructural defects that manifest as early damage and gradually transform into macro-damage under repeated traffic loads.
Convergent dopamine and ALK4 signaling to PCBP1 controls FosB alternative splicing and cocaine behavioral sensitization
Authors: Krapacher Favio A , Fernández‐Suárez Diana , Andersson Annika , Carrier‐Ruiz Alvaro , Ibáñez Carlos F 
Published: June 2022

AbstractΔfosB is an alternatively spliced product of the FosB gene that is essential for dopamine‐induced reward pathways and that acts as a master switch for addiction. However, the molecular mechanisms of its generation and regulation by dopamine signaling are unknown. Here, we report that dopamine D1 receptor signaling synergizes with the activin/ALK4/Smad3 pathway to potentiate the generation of ΔFosB mRNA in medium spiny neurons (MSNs) of the nucleus accumbens (NAc) via activation of the RNA‐binding protein PCBP1, a regulator of mRNA splicing. Concurrent activation of PCBP1 and Smad3 by D1 and ALK4 signaling induced their interaction, nuclear translocation, and binding to sequences in exon‐4 and intron‐4 of FosB mRNA. Ablation of either ALK4 or PCBP1 in MSNs impaired ΔFosB mRNA induction and nuclear translocation of ΔFosB protein in response to repeated co‐stimulation of D1 and ALK4 receptors. Finally, ALK4 is required in NAc MSNs of adult mice for behavioral sensitization to cocaine. These findings uncover an unexpected mechanism for ΔFosB generation and drug‐induced sensitization through convergent dopamine and ALK4 signaling.
Customary Delict of Penglipuran Bali in the Perspective of the Principle of Legality: A Dilemma and Arrangements for the Future
Authors: Adhari Ade , Widyawati Anis , Windia I Wayan P , Hutabarat Rugun Romaida , Tania Neysa 
Published: June 2022

In the context of criminal law, recognition of customary law begins with a very fundamental principle, namely the principle of legality – a legal basis for declaring an act as a criminal act. This paper examines the implementation of customary law regarding the violation of Penglipuran customary, in accordance with the customary delict from the perspective of the principle of legality and the future policy formulation of the principle of legality that accommodates the existence of customary law. To answer these problems, socio-legal research methods are used, data in the form of legal documents and results of in-depth interviews, various approaches (legal, theoretical, and historical approaches) and then analyzed through deductive-inductive methods. The results show that the Criminal Code adheres to the principle of formal legality, consequently, the written law is the only source to declare an act as an offense. Whereas in the Penglipuran community, it is known that customary delict is regulated not only in awig-awigbut also unwritten ones such as pararem penyahcah awig and perarem ngele. The existence of indigenous peoples is not only found textually but also commonly, carrying out their lives based on customary law which contains applicable values, principles, and norms. Therefore, it is necessary to formulate the principle of legality that accommodates the existence of customary law as a source of criminalizing acts. This is intended to realize a criminal law that accommodates the rights of indigenous peoples to “their own institutions, laws, and customs".