bluuebunny/crossref_metadata_2025_split huggingface dataset:
O Direito Humano à Audiência no Processo
Authors: Forster João Paulo Kulczynski , Schäfer Gilberto , Previdelli José Eduardo Aidikaitis , Buralde Camila Mousquer 
Published: September 2022

O estudo propõe o exame das audiências por videoconferência durante o estado declarado de pandemia pela Organização Mundial da Saúde. Para tanto, examina o próprio direito humano à audiência, que também possui feição fundamental, em seu formato que representa novo paradigma brasileiro: a forma eletrônica. Nesse contexto, apresenta a estrutura normativa nacional, consubstanciada da legislação processual e nas disposições do Conselho Nacional de Justiça, voltada à prática de atos na forma eletrônica, inclusive as audiências por videoconferência. Ao fim, apresenta situações analisadas em outros países – EUA, Colômbia e Espanha – em cotejo com decisões nacionais em que são limitadas as hipóteses de cabimento desta modalidade de audiências em razão de outros direitos processuais, como a defesa e a prova. A videoconferência deve ser utilizada com parcimônia, de forma que seu emprego não resulte em violação de direito das partes, em especial réus em processos de natureza criminal. Foi empregado o método indutivo, a partir de pesquisa exploratória bibliográfica em doutrina e legislação, assim como da análise de pesquisas e julgamentos estrangeiros.
Circle of Willis variation and outcome after intra-arterial treatment
Authors: Rozeman Anouk , Hund Hajo , Boiten Jelis , Vos Jan-Albert , Schonewille Wouter , Wermer Marieke , Lycklama a Nijeholt Geert , Algra Ale 
Published: September 2022

BackgroundIntra-arterial treatment (IAT) improves outcomes in acute ischaemic stroke. Presence of collaterals increases likelihood of good outcome. We investigated whether variations in the circle of Willis (CoW) and contributing carotid arteries influence outcome in patients who had a stroke treated with IAT.MethodsCT angiography data on patients who had an acute stroke treated with IAT were retrospectively collected. CoW was regarded complete if the contralateral A1 segment, anterior communicating artery and ipsilateral posterior communicating artery were fully developed, and the P1 segment was visible. Carotid artery contribution was studied with a self-developed carotid artery score ranging from 0 to 2 depending on the number of arteries supplying the occluded side of the CoW. Good clinical outcome was defined as modified Rankin Score ≤2 and measured at discharge and 3 months. We calculated risk ratios for the relation between completeness of the CoW, carotid score and good outcome, and performed a trend analysis for good outcome according to the carotid score.Results126 patients were included for analysis. Patients with a complete and incomplete CoW had a comparable risk for good outcome at discharge and 3 months. A higher carotid score was associated with a higher likelihood of good clinical outcome (p for trend 0.24 at discharge and 0.05 at 3 months).ConclusionIn patients with acute ischaemic stroke treated with IAT, chances of good clinical outcome tended to improve with number of carotid arteries supplying the cerebral circulation. Completeness of the CoW was not related to clinical outcome.
Consensus on how to optimise patient/family engagement in hospital planning and improvement: a Delphi survey
Authors: Anderson Natalie N , Baker G Ross , Moody Lesley , Scane Kerseri , Urquhart Robin , Wodchis Walter P , Gagliardi Anna R 
Published: September 2022

ObjectivePatient and family engagement (PE) in health service planning and improvement is widely advocated, yet little prior research offered guidance on how to optimise PE, particularly in hospitals. This study aimed to engage stakeholders in generating evidence-informed consensus on recommendations to optimise PE.DesignWe transformed PE processes and resources from prior research into recommendations that populated an online Delphi survey.Setting and participantsPanellists included 58 persons with PE experience including: 22 patient/family advisors and 36 others (PE managers, clinicians, executives and researchers) in round 1 (100%) and 55 in round 2 (95%).Outcome measuresRatings of importance on a seven-point Likert scale of 48 strategies organised in domains: engagement approaches, strategies to integrate diverse perspectives, facilitators, strategies to champion engagement and hospital capacity for engagement.ResultsOf 50 recommendations, 80% or more of panellists prioritised 32 recommendations (27 in round 1, 5 in round 2) across 5 domains: 5 engagement approaches, 4 strategies to identify and integrate diverse patient/family advisor perspectives, 9 strategies to enable meaningful engagement, 9 strategies by which hospitals can champion PE and 5 elements of hospital capacity considered essential for supporting PE. There was high congruence in rating between patient/family advisors and healthcare professionals for all but six recommendations that were highly rated by patient/family advisors but not by others: capturing diverse perspectives, including a critical volume of advisors on committees/teams, prospectively monitoring PE, advocating for government funding of PE, including PE in healthcare worker job descriptions and sharing PE strategies across hospitals.ConclusionsDecision-makers (eg, health system policy-makers, hospitals executives and managers) can use these recommendations as a framework by which to plan and operationalise PE, or evaluate and improve PE in their own settings. Ongoing research is needed to monitor the uptake and impact of these recommendations on PE policy and practice.
Training inhibitory control in adolescents with elevated attention deficit hyperactivity disorder traits: a randomised controlled trial of the Alfi Virtual Reality programme
Authors: McKay Erin , Kirk Hannah , Coxon James , Courtney Danielle , Bellgrove Mark , Arnatkeviciute Aurina , Cornish Kim 
Published: September 2022

IntroductionAttention deficit hyperactivity disorder (ADHD) is characterised by significant deficits in attention and inhibition. These deficits are associated with negative sequelae that emerge in childhood and often continue throughout adolescence. Despite these difficulties adolescents with ADHD often demonstrate poor treatment compliance with traditional interventions (eg, psychostimulant medication). Virtual reality (VR) presents an innovative means of delivering engaging cognitive interventions for adolescents with ADHD and offers the potential to improve compliance with such interventions. The current parallel, randomised controlled trial aims to evaluate the effects of a VR intervention (Alfi) designed to improve inhibition in adolescents with ADHD.Methods and analysisA sample of 100 adolescents (aged 13–17) with elevated ADHD symptoms will be recruited from secondary schools and ADHD organisations located in the state of Victoria, Australia. Participants will be randomly assigned to either an 8-week VR intervention or a usual care control. The VR intervention involves the completion of 14 sessions, each 20 min in duration. Participants will complete computerised assessments of inhibition and risk-taking preintervention and immediately postintervention. Parents/guardians will complete online questionnaires about their child’s ADHD symptoms and social functioning at each of these timepoints. The primary outcome is change in inhibition performance in adolescents who received the intervention from preintervention to postintervention compared with adolescents in the control condition. Secondary outcomes include change in risk-taking, ADHD symptoms and social functioning in adolescents who received the intervention from preintervention to postintervention compared with adolescents in the control condition. If the intervention is shown to be effective, it may offer a supplementary approach to traditional interventions for adolescents with ADHD experiencing inhibitory control difficulties.Ethics and disseminationThis trial has ethics approval from the Monash University Human Research Ethics Committee (HREC) (21530) and the Victorian Department of Education and Training HREC (2020_004271). Results will be disseminated through peer-reviewed journals, conference proceedings and community activities. Individual summaries of the results will be provided to participants on request.Trial registration numberACTRN12620000647932.
Perceptions of generic medicines and medication adherence after percutaneous coronary intervention: a prospective multicentre cohort study
Authors: Pettersen Trond Røed , Schjøtt Jan , Allore Heather G , Bendz Bjørn , Borregaard Britt , Fridlund Bengt , Larsen Alf Inge , Nordrehaug Jan Erik , Rotevatn Svein , Wentzel-Larsen Tore , Norekvål Tone Merete 
Published: September 2022

ObjectiveTo determine patient perceptions of generic medicines 2 and 6 months after percutaneous coronary intervention (PCI), and to determine whether these perceptions moderate medication adherence.DesignProspective multicentre cohort study with repeated measures of perceptions of generic medicines and medication adherence.SettingThe CONCARDPCI study conducted at seven large referral PCI centres in Norway and Denmark between June 2017 and May 2020.ParticipantsA total of 3417 adults (78% men), using both generic and brand name medicines, with a mean age of 66 years (SD 11) who underwent PCI were followed up 2 and 6 months after discharge from hospital.Main outcome measuresPerceptions of generic medicines were the main outcome. The secondary outcome was medication adherence.ResultsPerceptions of generic medicines were significantly more negative at 2 than at 6 months (1.10, 95% CI 0.41 to 1.79, p=0.002). Female sex (−4.21, 95% CI −6.75 to −1.71, p=0.001), older age (−0.12, 95% CI −0.23 to −0.02, p=0.020), lower education level (overall p<0.001), ethnicity (overall p=0.002), Norwegian nationality (10.27, 95% CI 8.19 to 12.40, p<0.001) and reduced self-reported health status (0.19, 95% CI 0.09 to 0.41, p=0.003) were significantly associated with negative perceptions of generic medicines. There was no evidence to suggest that perceptions of generic medicines moderate the association between sociodemographic and clinical variables and medication adherence (p≥0.077 for all covariates). Moreover, self-reported medication adherence was high, with 99% scoring at or above the Medication Adherence Report Scale midpoint at both time points. There were no substantial correlations between negative perceptions of generic medicines and medication non-adherence at 2 months (r=0.041, 95% CI 0.002 to 0.081, p=0.037) or 6 months (r=0.038, 95% CI −0.005 to 0.081, p=0.057).ConclusionsMistrust and uncertainty about the safety and efficacy of generic medicines remains in a sizeable proportion of patients after PCI. This applies especially to those of lower socioeconomic status, older age, female sex, immigrants and those with poorer mental health. However, this study demonstrated a shift towards more positive perceptions of generic medicines in the longer term.
Realist inquiry into Maternity care @ a Distance (ARM@DA): realist review protocol
Authors: Evans Catrin , Evans Kerry , Booth Andrew , Timmons Stephen , Jones Nia , Nazmeen Benash , Sunney Candice , Clowes Mark , Clancy Georgia , Spiby Helen 
Published: September 2022

IntroductionOne of the most commonly reported COVID-19-related changes to all maternity services has been an increase in the use of digital clinical consultations such as telephone or video calling; however, the ways in which they can be optimally used along maternity care pathways remain unclear. It is imperative that digital service innovations do not further exacerbate (and, ideally, should tackle) existing inequalities in service access and clinical outcomes. Using a realist approach, this project aims to synthesise the evidence around implementation of digital clinical consultations, seeking to illuminate how they can work to support safe, personalised and appropriate maternity care and to clarify when they might be most appropriately used, for whom, when, and in what contexts?Methods and analysisThe review will be conducted in four iterative phases, with embedded stakeholder involvement: (1) refining the review focus and generating initial programme theories, (2) exploring and developing the programme theories in light of evidence, (3) testing/refining the programme theories and (4) constructing actionable recommendations. The review will draw on four sources of evidence: (1) published literature (searching nine bibliographic databases), (2) unpublished (grey) literature, including research, audit, evaluation and policy documents (derived from Google Scholar, website searches and e-thesis databases), (3) expertise contributed by service user and health professional stakeholder groups (n=20–35) and (4) key informant interviews (n=12). Included papers will consist of any study design, in English and from 2010 onwards. The review will follow the Realist and Meta-narrative Evidence Synthesis Evolving Standards quality procedures and reporting guidance.Ethics and disseminationEthical approval has been obtained from the University of Nottingham, Faculty of Medicine and Health Sciences Ethics Committee (FMHS 426–1221). Informed consent will be obtained for all key informant interviews. Findings will be disseminated in a range of formats relevant to different audiences.PROSPERO registration numberCRD42021288702.
Preventive strategies of cancer therapeutics-related cardiotoxicity in childhood cancer survivors: a protocol of systematic review
Authors: Zhang Xin-Yu , Wang Quan , Yang Ke-Lu , Wei Dang , Liu Xiao-Nan 
Published: September 2022

IntroductionFive-year survival in childhood cancer has been improved markedly in the past decades. Childhood cancer survivors are at high risk of cardiovascular diseases due to anticancer therapy-induced cardiotoxicity. The comprehensive evidence for the prevention of anticancer therapy-induced cardiovascular disease is, however, sparse. The systematic review described in the protocol aims to summarise the effect of current prevention for anticancer therapy-induced cardiotoxicity among childhood cancer survivors.Methods and analysisThis protocol is reported in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols checklist. We will search PubMed (via Medline), Embase and the Cochrane Library and include the studies investigating the effect of prevention against anticancer therapy-induced cardiotoxicity of childhood cancer. To assess the risk of bias, we will use the Cochrane Collaboration’s risk of bias tool for randomised control trials and the Newcastle-Ottawa Scale for cohort studies and case–control studies. Furthermore, we will conduct meta-analyses if there is no substantial clinical heterogeneity between included studies. The Grading of Recommendations, Assessment, Development and Evaluation will be used to evaluate the quality of evidence.Ethics and disseminationEthical approval is not needed for systematic review of published data. The findings will be published in a peer-reviewed journal and disseminated at scientific conferences.PROSPERO registration numberCRD42022333877.
Gastro-oesophageal reflux disease in children with neurological impairment: a retrospective cohort study
Authors: Dewan Tammie , Turner Justine , Lethebe Brendan Cord , Johnson David W 
Published: September 2022

ObjectivesTo determine the incidence and prevalence of gastro-oesophageal reflux disease (GERD) diagnosis and treatment in children with neurological impairment (NI) along with relationship to key variables.DesignThis is a population-based retrospective cohort study.SettingThis study takes place in Alberta, Canada.PatientsChildren with NI were identified by hospital-based International Classification of Diseases (ICD) codes from 2006 to 2018.Main outcome measuresIncidence and prevalence of a GERD diagnosis identified by: (1) hospital-based ICD-10 codes; (2) specialist claims; (3) dispensation of acid-suppressing medication (ASM). Age, gender, complex chronic conditions (CCC) and technology assistance were covariates.ResultsAmong 10 309 children with NI, 2772 (26.9%) met the GERD definition. The unadjusted incidence rate was 52.1 per 1000 person-years (50.2–54.1). Increasing numbers of CCCs were associated with a higher risk of GERD. The HR for GERD associated with a gastrostomy tube was 4.56 (95% CI 4.15 to 5.00). Overall, 2486 (24.1%) of the children were treated with ASMs of which 1535 (61.7%) met no other GERD criteria. The incidence rate was 16.9 dispensations per year (95% CI 16.73 to 17.07). The prevalence of gastrojejunostomy tubes was 1.1% (n=121), surgical jejunostomy tubes was 0.7% (n=79) and fundoplication was 3.4% (n=351).ConclusionsThe incidence of GERD in children with NI greatly exceeds that of the general paediatric population. Similarly, incidence rate of medication dispensations was closer to the rates seen in adults particularly in children with multiple CCCs and gastrostomy tubes. Further research is needed to determine the appropriate use of ASMs balancing the potential for adverse effects in this population.
Clinician’s guide to the basic principles of MRI
Authors: Azhar Syifa , Chong Le Roy 
Published: September 2022

Abstract
MRI is an important and widely used imaging modality for clinical diagnosis. This article provides a concise discussion of the basic principles of MRI physics for non-radiology clinicians, with a general explanation of the fundamentals of signal generation and image contrast mechanisms. Common pulse sequences, tissue suppression techniques and use of gadolinium contrast with relevant clinical applications are presented. Knowledge of these concepts would provide an appreciation of how MR images are acquired and interpreted to facilitate interdisciplinary understanding between radiologists and referring clinicians.
Arthropod-borne encephalitis: an overview for the clinician and emerging considerations
Authors: Boruah Abhilasha Pankaj , Thakur Kiran T 
Published: September 2022

Abstract
The rapid spread of arboviral infections in recent years has continually established arthropod-borne encephalitis to be a pressing global health concern. Causing a wide range of clinical presentations ranging from asymptomatic infection to fulminant neurological disease, the hallmark features of arboviral infection are important to clinically recognise. Arboviral infections may cause severe neurological presentations such as meningoencephalitis, epilepsy, acute flaccid paralysis and stroke. While the pathogenesis of arboviral infections is still being investigated, shared neuroanatomical pathways among these viruses may give insight into future therapeutic targets. The shifting infection transmission patterns and evolving distribution of arboviral vectors are heavily influenced by global climate change and human environmental disruption, therefore it is of utmost importance to consider this potential aetiology when assessing patients with encephalitic presentations.
Functional renormalization of spinless triangular-lattice fermions: N-patch vs. truncated-unity scheme
Authors: Gneist Nico , Kiese Dominik , Henkel Ravn , Thomale Ronny , Classen Laura , Scherer Michael M. 
Published: September 2022

Abstract
We study competing orders of spinless fermions in the triangular-lattice Hubbard model with nearest-neighbor interaction. We calculate the effective, momentum-resolved two-particle vertex in an unbiased way in terms of the functional renormalization group method and compare two different schemes for the momentum discretization, one based on dividing the Fermi surface into patches and one based on a channel decomposition. We study attractive and repulsive nearest-neighbor interaction and find a competition of pairing and charge instabilities. In the attractive case, a Pomeranchuk instability occurs at Van Hove filling and f-wave and p-wave pairing emerge when the filling is reduced. In the repulsive case, we obtain a charge density wave at Van Hove filling and extended p-wave pairing with reduced filling. The p-wave pairing solution is doubly degenerate and can realize chiral $$p+ip$$

p
+
i
p

superconductivity with different Chern numbers in the ground state. We discuss implications for strongly correlated spin-orbit coupled hexagonal electron systems such as moiré heterostructures.

Graphic Abstract
A Cross-Sectional Study of the Prevalence of Anal Dysplasia among Women with High-Grade Cervical, Vaginal, and Vulvar Dysplasia or Cancer: The PANDA Study
Authors: Batman Samantha , Messick Craig A. , Milbourne Andrea , Guo Ming , Munsell Mark F. , Fokom-Domgue Joel , Salcedo Mila , Deshmukh Ashish , Dahlstrom Kristina R. , Ogburn Mallory , Price Anthony , Fleming Nicole D. , Taylor Jolyn , Shafer Aaron , Cobb Lauren , Sigel Keith , Sturgis Erich M. , Chiao Elizabeth Y. , Schmeler Kathleen M. 
Published: September 2022

Background:
High-risk human papillomavirus (HR-HPV) infection is a risk factor for anal cancer, yet no anal cancer screening guidelines exist for women with lower genital tract HPV-related disease. We sought to describe the prevalence of anal HR-HPV or cytologic abnormalities in such women.

Methods:
This cross-sectional study was performed between October 2018 and December 2021. Inclusion criteria were ≥21 years of age and a prior diagnosis of high-grade dysplasia/cancer of the cervix, vagina, or vulva. Participants underwent anal cytology and anal/cervicovaginal HR-HPV testing. Women with abnormal anal cytology were referred for high-resolution anoscopy (HRA).

Results:
324 evaluable women were enrolled. Primary diagnosis was high-grade dysplasia/cancer of the cervix (77%), vagina (9%), and vulva (14%). Anal HR-HPV was detected in 92 patients (28%) and included HPV-16 in 24 (26%), HPV-18 in 6 (7%), and other HR-HPV types in 72 (78%) patients. Anal cytology was abnormal in 70 patients (23%) and included atypical squamous cells of undetermined significance (80%), low-grade squamous intraepithelial lesion (9%), high-grade intraepithelial lesion (HSIL; 1%), and atypical squamous cells-cannot rule out HSIL (10%). Of these patients, 55 (79%) underwent HRA. Anal biopsies were performed in 14 patients: 2 patients had anal intraepithelial neoplasia (AIN) 2/3, 1 patient had AIN 1, and 11 patients had negative biopsies. Both patients with AIN 2/3 had a history of cervical dysplasia.

Conclusions:
Our results suggest an elevated risk of anal HR-HPV infection and cytologic abnormalities in women with lower genital tract dysplasia/cancer.

Impact:
These results add to the growing body of evidence suggesting the need for evaluation of screening methods for anal dysplasia/cancer in this patient population to inform evidence-based screening recommendations.