bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spousal body weight concordance and the impact of spouse overweight on death risk: data form a 27-year cohort prospective study
Authors: Dolgalev I. V. , Ivanova A. Yu. , Karpov R. S. , Ovcharova P. A. 
Published: June 2022

Aim. To study the interdependence of spousal body mass and influence of spouse overweight on the death risk according to the 27-year cohort prospective study.Material and methods. We examined a random household sample (n=1546; married couples, 427). Overweight frequency among spouses was studied on the first stage of the study (1988-1991). In 2002-2005 (stage II), the examination was repeated and overweight dynamics were studied. In 2015 (stage III), we analyze mortality rates and significance of overweight and spousal overweight for the mortality risk formation. Overweight was detected in people with body mass index ≥25 kg/m2. Two hundred deaths were recorded during 27-year follow-up. Vital status was established for 97% of observed persons.Results. Overweight was detected in 61,1% of men who lived with overweight wife and in 45% of men whose wife had normal body mass (p<0,01). Overweight was diagnosed more often in women whose husband also had overweight comparing with women who lived with normal weight husband (76,2% vs 61,7%; p<0,001). The risk of overweight formation among individuals whose spouse’s body mass increased from norm to overweight was in 3,04 times higher than in persons whose spouse had a stable normal body mass and in 2,2 times higher than in participants whose spouse had overweight on study stages I and II. Relative risk of mortality in men who lived with overweight wife was 2,07.Conclusion. 1) We found the body mass concordance in spouses. 2) The average body mass index in men and women who lived with overweight spouse is higher than in men and women whose spouse had a normal body mass. 3) Interdependence of spousal body mass was revealed in dynamics. 4) Spousal overweight is an independent predictor of premature mortality in men.
Prevalence of carbohydrate metabolism disorders and association with cardiovascular diseases in a large Siberian region
Authors: Shabalin V. V. , Grinshtein Yu. I. , Ruf R. R. , Filonenko I. V. , Shalnova S. A. , Drapkina O. M. 
Published: June 2022

Aim. To study the prevalence of carbohydrate metabolism disorders in a repre - sentative sample of the working-age population of the Krasnoyarsk Krai aged 25-64 years and to identify the association of these disorders with cardiovascular pathology.Material and methods. A random representative sample within the all-Russian epidemiological study ESSE-RF included 1603 residents of the Krasnoyarsk Krai aged 25 to 64 years. The gradation of carbohydrate metabolism disorders was carried out on the basis of fasting plasma glucose level in accordance with the criteria of the American Diabetes Association (ADA). Hypertension (HTN) was defined as office BP ≥140/90 mm Hg or an indication of previous use of antihypertensive drugs. The presence of myocardial infarction (MI), stroke, coronary artery disease (CAD) was detected by anamnesis collection. Statistical processing was carried out using IBM SPSS v 22 and Microsoft Excel 2021 programs. When comparing differences by sex, age, level of education, and type of residence, differences was assessed by chi-squared test and considered significant at p≤0,05.Results. In total representative sample of Krasnoyarsk Krai population, 3,6% of participants indicated prior diabetes, while its prevalence naturally increased with age. The detection rate of fasting glucose of 5,6-6,9 mmol/l among individuals without prior diabetes (impaired fasting glycemia (IFG), as one of the criteria for prediabetes, according to ADA guidelines) was 22,5% of the general population. Fasting hyperglycemia (HG) ≥7,0 mmol/l without prior diabetes was registered in 3,8%. This figure can be roughly considered as the proportion of people with newly diagnosed diabetes. IFG and HG were significantly more common among men, as well as among those with primary and secondary education compared with higher education. In rural residents, all types of carbohydrate metabolism disorders were more common than in urban ones. Compared with the normoglycemic group, the presence of prior diabetes, IFG and GH was associated with a significantly higher prevalence of hypertension, CAD and stroke.Conclusion. The prevalence of IFG, fasting HG ≥7,0 mmol/l and diagnosed diabetes in a representative sample of the Krasnoyarsk Krai aged 25-64 years exceeds the national average, although it is consistent with the data of a number of other Siberian regions. The prevalence of both carbohydrate metabolism disorders in general and the percentage of possible undiagnosed diabetes increases with age. At the same time, there are more such individuals among those with primary and secondary education, as well as among rural residents. The approximate proportion of undiagnosed diabetes in the study population reaches 50%. Timely detection of carbohydrate metabolism disorders can contribute to the earlier implementation of active preventive measures and reduce the risk of cardiovascular events.
Behavioral and social risk factors for metabolically unhealthy obesity: data form a 12-year prospective study in the Russian population
Authors: Vinter D. A. , Mustafina S. V. , Rymar O. D. , Avdeeva E. M. , Shcherbakova L. V. , Malyutina S. K. 
Published: June 2022

Aim. To study the contribution of behavioral and social risk factors to the development of metabolically unhealthy obesity (MUO) according to a prospective study in the Russian population.Material and methods. From the HAPPIE project, 3197 people aged 45-69 years with a body mass index ≥30 kg/m2 were selected, who had all the necessary parameters for obesity phenotype determination. The prospective analysis included the first (2003-2005) and third screenings (2015-2017). A subsample was formed (n=1275; 276 men — 22%, 999 women — 78%). The mean follow-up period was 12,4 years. IDF criteria (2005) were taken for analysis.Results. Men with a metabolically healthy obesity (MHO) phenotype most often have a secondary and higher education, while women with MHO — vocational and secondary education. In women, secondary education was most often noted. Among persons with obesity, both men and women are more often not single, while having MUO as follows: 56,8% and 34,2%, respectively. Men and women have a low-intensity activity, regardless of the obesity phenotype. The prevalence of smoking in the present time does not differ in the MHO and MUO groups. Metabolically healthy women consume more alcohol than those with MUO. In men with sedentary lifestyle and fasting hyperglycemia, the risk of MUO over a 12-year follow-up period was significantly higher. In women, the risk of conversion from MHO to MUO is increased when blood pressure (BP) is ≥130/85 mmHg.Conclusion. In the Russian population, the risk of MUO in men increases with a level of physical activity <3 h/week and a blood glucose level ≥6,1 mmol/l; in women, only BP ≥130/85 mm Hg contributes to the development of MUO.
Results of a 7-year prospective follow-up in the Interepid study: factors influencing all-cause and cardiovascular mortality in rural residents of Russia and the Kyrgyz Republic
Authors: Myrzamatova A. O. , Kontsevaya A. V. , Polupanov A. G. , Altymysheva A. T. , Kashirin A. K. , Sirotko M. L. , Drapkina O. M. 
Published: June 2022

Aim. To assess the 7-year survival rate and the association of risk factors (RFs) with all-cause and cardiovascular mortality among rural residents in Russia and the Kyrgyz Republic, as well as to analyze ethnic characteristics (according to the Interepid study).Material and methods. This study was carried out within the Interepid international project, which included a cross-sectional epidemiological study of the prevalence of major noncommunicable diseases and their risk factors in 2011- 2012, and a prospective stage among rural residents of two countries (Russia, the Kyrgyz Republic). In 2019, the vital status of respondents was reassessed (7 years after the initial examination), and endpoints were collected, including all-cause and cardiovascular deaths.Results. A significant similarity of rural residents of the analyzed regions in relation to the factors associated with mortality was revealed. Smoking in men, obesity in women, and hypertension in both sexes were associated with an increased death risk. Country differences were found only in relation to low physical activity and dietary habits. Ethnic developments in the population of the Kyrgyz Republic also concerned only the contribution of food habits.Conclusion. The results obtained are important for planning, implementing and evaluating the effectiveness of public health promotion programs. It is also necessary to develop differentiated treatment and prevention measures in the Russian population and among the indigenous inhabitants of the Kyrgyz Republic, including taking into account the prevalence of CVD risk factors and their impact on life prognosis.
Analysis of factors associated with arterial stiffness in the general working-age population
Authors: Kaveshnikov V. S. , Trubacheva I. A. , Serebryakova V. N. 
Published: June 2022

Aim. To examine associations of cardio-ankle vascular index (CAVI) with classical, behavioral and social risk factors (RFs) of cardiovascular disease (CVD) in adult population.Material and methods. The study included 1365 people (women, 59%) from a representative sample aged 25-64 years (ESSE-RF), who underwent standard cardiology screening and volume sphygmography (VaSera-1500). All respondents signed an informed consent to participate in the study. The analysis included blocks of classical, social and behavioral risk factors for CVD. A linear model was used to identify associations. An error rate of <5% was considered significant.Results. Age, sex, systolic blood pressure (SBP), triglycerides were associated with higher CAVI values, and body mass index (BMI) was associated with lower values, respectively. After 45 years, a direct association with heart rate (HR) became increasingly important, while after 50 years — with diabetes and the intake of beta-blockers, while the association between diabetes and CAVI was observed only among individuals not taking angiotensin-converting enzyme (ACE) inhibitors. A direct association was found with high-sensitivity C-reactive protein (hsCRP) in men, and an inverse association with diuretics in women, respectively. A sedentary work in combination with a history of bronchitis or with positive family history for CVD showed a direct relationship, while a sufficient physical activity (PA) showed an inverse relationship with the studied indicator, but only among people with belowaverage income.Conclusion. According to the data obtained, in addition to age and sex, the following risk factors made a significant contribution to CAVI parameters in the examined population: BMI, SBP, triglycerides, diabetes, HR, intake of betablockers, diuretics, ACE inhibitors; hsCRP, PA. The unfavorable role of betablockers, high HR, diabetes, sedentary work, chronic lung pathology, hereditary burden, as well as the protective role of ACE inhibitors, diuretics and intense PA in relation to arterial stiffness in the working-age population has been shown. Additional studies are needed to determine the nature of a number of associations. The results obtained may contribute to the study of CAVI role in risk stratification and further development of methodological approaches to CVD prevention.
CarotidSCORE.RU — risk stratification for complications after carotid endarterectomy
Authors: Kazantsev A. N. , Khasanova D. D. , Alpatskaya A. D. , Korotkikh A. V. , Dzhanelidze M. O. , Rusakova M. A. , Kharchilava E. U. , Sulimenko M. V. , Lutsenko V. A. , Sultanov R. V. , Alizada F. R. , Meleshin E. O. , Ginzburg E. R. , Gofman A. E. , Alekseeva E. O. , Lider R. Yu. , Pivovarov A. A. , Zakeryaev A. B. , Bagdavadze G. Sh. , Makoeva M. M. , Klimova A. I. , Zharova A. S. , Chernyavtsev I. A. , Abramov O. O. , Zakharova K. L. , Radzhabov I. M. , Karmokov I. A. , Kuklev A. P. , Solotenkova K. N. , Pachkoria M. G. , Sem’in I. S. , Kostenkov A. A. , Chernykh K. P. 
Published: June 2022

Aim. To demonstrate the first Russian computer program (carotidscore.ru) for risk stratification of postoperative complications of carotid endarterectomy (CE).Material and methods. The present study is based on the analysis of a multicenter Russian database including 25812 patients after CE operated on from January 1, 2010 to April 1, 2022. The following types of CE were implemented: conventional CE with patch angioplasty — 6814 patients; eversion CE — 18998 patients. Following postoperative complications were assessed during the study: death, stroke, myocardial infarction (MI), composite endpoint (death + stroke + MI).Results. During inhospital postoperative period, 0,18% of participants died, while 0,14% had MI, 0,35% — stroke. The composite endpoint was recorded in 0,68%. For each factor present in patients, a predictive coefficient was estimated. The predictive coefficient was considered as a numerical parameter reflecting the strength of the effect of each factor on the development of postoperative complications. Based on this equation, predictive coefficients were calculated for each factor present in patients in our study. The total contribution of these factors was reflected as a percentage and denoted the risk of postoperative complications with a minimum of 0% and a maximum of 100%. On the basis of obtained calculations, a CarotidSCORE program was created. Its graphical interface is based on the QT framework. It is possible not only to estimate the risk of a complication, but also to save all data about a patient in JSON format. The CarotidSCORE program contains 47 patient parameters, including clinical, demographic, anamnestic and angiographic characteristics. It makes it possible to choose one of the four CE types, which will provide an accurate stratification of the complication risk for each of them.Conclusion. CarotidSCORE (carotidscore.ru) may determine the probability of postoperative complications in patients undergoing CE.
Do chemistry and rheology follow the same laboratory ageing trends in bitumen?
Authors: Pipintakos Georgios , Lommaert Caitlin , Varveri Aikaterini , Van den bergh Wim 
Published: June 2022

AbstractThe ageing of bitumen has received great attention both from a chemical and rheological perspective due to its direct impact on asphalt performance. However, open questions with respect to the convergence of the synchronous ageing changes in rheology and chemistry of bitumen still exist. This paper addresses these alterations of chemistry and rheology and attempts to establish a link via fitting rheological equations fed by fundamental chemical information. To that end, three binders of different type were used in four different laboratory ageing states. A number of spectroscopic techniques and rheological testing were employed to derive corresponding chemical and rheological parameters. In parallel, various statistical methods (Bivariate analysis, Wilcoxon test, Factor analysis) assisted in identifying relationships among the chemo-rheological parameters and simplifying the number of variables. The results of this study demonstrate that chemistry and rheology are following similar changes when considering laboratory ageing following the fast-rate phase of a dual oxidation scheme and short-term lab ageing. Finally, this work manages to establish a linking framework for a number of newly-introduced rheological parameters. All in all, the results of this study might be particularly interesting for future interventions in the chemical composition of bitumen, considering its effect on performance.
Adaptive State Observer for Linear Time-Varying System with Partially Unknown State Matrix and Input Matrix Parameters
Authors: Bobtsov A. A. , Nikolaev N. A. , Ortega R. , Slita O. V. , Kozachek O. A. 
Published: June 2022

In this paper the problem of adaptive state observer synthesis for linear time-varying SISO (single-input-single-output) dynamical system with partially unknown parameters was considered. It is assumed that the input signal and output variable of the system are measurable. It is also assumed that the state matrix of the plant contains known variables and unknown constants when the input matrix (vector) is unknown. Observer synthesis is based on GPEBO (generalized parameter estimation based observer) method proposed in [1]. Observer synthesis provides preliminary parametrization of the initial system and its conversion to a linear regression model with further unknown parameters identification. For identification of the unknown constant parameters classical estimation algorithm — least squares method with forgetting factor — was used. This approach works well in cases, when the known regressor is " frequency poor" (i.e. the regressor spectrum contains r/2 harmonics, where r is a value of the unknown parameters) or does not meet PE (persistent excitation) condition. To illustrate performance of the proposed method, an example is provided in this paper. A time-varying second-order plant with four unknown parameters was considered. Parametrization of the initial dynamical model was made. A linear static regression with six unknown parameters (including unknown state initial conditions vector) was obtained. An adaptive observer was synthesized and the simulation results were provided to illustrate the purpose reached. The main difference with the results, that were published earlier in [2], is the new assumption that not only does the state matrix of the linear time-varying system contain unknown parameters, but input matrix (vector) contains unknown constant coefficients.
Synthesis of a Fuzzy Controller According to the Degree of Stability of the Control System
Authors: Bykovtsev Y. A. 
Published: June 2022

The article is devoted to solving the problem of analysis and synthesis of a control system with a fuzzy controller (fuzzy control system) in terms of the degree of stability. As interest in fuzzy control systems grows, various approaches to the study of such systems are being developed more and more actively. One of the most actively developing areas is based on the modification of methods for assessing the stability regions of nonlinear ACS, however, when solving most practical problems, this knowledge is not enough, since the developer needs to provide the required qualitative characteristics of the transient process (and, in particular, the control time). Therefore, the synthesis of fuzzy ACS in terms of the degree of stability seems to be quite constructive, since it allows quite accurately assessing the performance of a fuzzy ACS. The proposed solution is based on the criterion of absolute stability for a system with an approximated nonlinear characteristic of a fuzzy controller, which can be obtained directly on the basis of the Sugeno method. The article develops Yakubovich’s circular criterion of absolute stability, modified for a fuzzy control system, using a shifted AFC of the linear part. With this approach, it is possible to obtain a completely constructive solution to the problem of synthesizing the parameters of a fuzzy controller in the frequency domain. On the example of fuzzy control systems with static and astatic linear parts, the features of the application of the developed approach are shown and methods for synthesizing the parameters of a fuzzy controller are proposed. The analysis of the influence of individual components of the nonlinear transformation on the quality of the transient process is carried out, and on the basis of this a number of practical recommendations are given for correcting the fuzzy controller settings that provide the required performance.
Synergetic Model of Situational Awareness of a Human Operator in Ergatic Control Systems of Mobile Objects
Authors: Suyatinov S. I. , Buldakova T. I. , Vishnevskaya Yu. A. 
Published: June 2022

At present, researches of ergatic control systems for moving objects, in which an important role is assigned to the human operator, are of particular relevance. The effectiveness of the functioning of such systems largely depends on the state of the human operator and, first of all, on his situational awareness. Insufficient or inadequate awareness of the operator about the situation in such systems is one of the main factors of accidents associated with human error. Therefore, the task of creating models of professional activity of a human operator, including models of his situational awareness, is urgent. It is shown that situational awareness is based on mental models of a human operator. Their adequacy depends on many subjective characteristics (factors) peculiar to a person, for example, his intelligence, mental state, accumulated experience. Mathematical formalization will reduce the subjective component in the formation of situational awareness. It is noted that important properties of situational awareness of the human operator are associativity and ranking of information depending on the context of the problem being solved. Therefore, situational awareness provides perception of the current situation and allows you to make the right decisions in response to certain threats. The levels of implementation of situational awareness in a human operator are given. A feature of the first level is the need for joint processing of a large amount of heterogeneous information in order to identify significant facts and critical information about external objects. The task of the second level is to form a holistic picture of the situation, which is based on existing knowledge and previous experience. The third, highest level of understanding of the situation is based on the ability of a person to predict the actions of moving objects and the consequences of these actions. It is proposed to form a model of situational awareness based on Haken’s synergetic approach. Like most other intelligent systems, the synergetic Haken’s model includes learning and recognition processes. A description of the process of recognizing a critical situation using a trained synergetic model is given. The value of the attention parameter, which characterizes the importance of a specific characteristic of the state of the controlled object in the ergatic system, is noted. The associative properties of the synergetic model and its ability to rank the initial information in the process of threat analysis during helicopter control are investigated.