bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diffusion-weighted image versus contrast-enhanced kinetic curves
Authors: Abokhozayem Salma A.A.N. , Mohammed Hosnia A. , Osama Sally M. 
Published: September 2022

Background and aim
Noninvasive radiological techniques such as dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted imaging (DWI) can help distinguish between malignant and benign lesions of the breast. The current study was conducted to evaluate the diagnostic values of DCE-MRI and DWI in differentiation between benign and malignant breast lesions.

Patients and methods
This study was conducted on 30 patients with 32 lesions during the period from June 2019 to May 2020 at the Radiology Department and approved by the Ethics Committee. DCE-MRI and DWI were acquired for each patient using a 1.5 T machine with breast coils. Histopathological results were collected as a gold standard of the study.

Results
Of 32 lesions, histopathology revealed that 22 (68.75%) lesions were malignant and 10 (31.25%) lesions were benign. Mean apparent diffusion coefficient (ADC) of benign lesions was 1.25±0.56×10−3 mm2/s, which was significantly higher than those of malignant lesions (0.93±0.42×10−3 mm2/s). DWI-MRI had high sensitivity, specificity, positive predictive value, negative predictive value, and accuracy in distinguishing benign from malignant lesions (90.9, 70, 86.96, 77.78, and 84.38%, respectively). However, the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of DCE-MRI were 95.5, 80, 91.3, 88.9, and 90.6%, respectively.

Conclusion
Compared with DWI, DCE-MRI has a higher sensitivity and specificity for distinguishing between benign and malignant lesions of the breast. Diffusion-weighted MRI provides quantitative assessment of benign and malignant lesions of the breast by measuring the ADC values.
A cross-sectional comparative analysis of corneal endothelial parameters by specular microscopy in post covid versus normal population in Western India
Authors: Kaushik Jaya , Singh Ankita , Anargh V , Riyaz Eram , Sathagopam Srikanth , Arun Kumar A S , Nair Renu , Aggarwal Ishan 
Published: September 2022

Abstract

Objective:
To observe the changes in corneal endothelium post COVID-19 infection in different age groups using specular microscopy and compare it with the normal population in western India during the pandemic.

Materials and Method:
129 patients COVID-19 recovered, and 123 age-matched healthy controls were included in this cross sectional, comparative, monocentric study. Corneal endothelial parameters like Cell Density (CD) (cell/mm2), Coefficient of Variation (CV) (polymegathism, %), Cell hexagonality (polymorphism, %), Average cell area (MCA) (μm2/cell), and mean value of Central Corneal Thickness (CCT) (μm) were evaluated with a non-contact specular microscope (TOMEY EM-4000, CBD.TOMEY USA)

Results:
The mean (SD) time since COVID diagnosis (months) in the study group was 6.67 (1.94). The mean (SD) time since RT-PCR negative (months) in the study group was 6.34 (1.74). The mean (SD) of CV (%) in the study group was (RE) 37.75 (6.03), (LE) 36.25 (4.66) and in control group was (RE) 35.23 (3.75), (LE) 34.77 (3.64). The mean (SD) of hexagonality (%) in the study group was (RE) 47.33 (6.84), 48.45 (7.33) and in control group was (RE):56.73 (4.13), (LE) 56.21 (5.34).

Conclusion:
The specular microscopic examination on the COVID-19 recovered patients revealed a decrease in the hexagonality of the endothelial cells (pleomorphism) and an increase in the cell size (polymegathism). Specular microscopic examination can be done to assess such earliest changes in corneal endothelium to evaluate the effects of the infection following recovery on ocular tissue to avoid long term sequalae.
An overview of microbiological profile in chronic microbial keratitis at a tertiary care center
Authors: Gupta Manisha , Gupta Priyanka , Panwar Juhi 
Published: September 2022

Abstract

Aims:
Clinical feature and microbiological investigation help in reaching the diagnosis in cases of microbial keratitis. But in cases where a patient is already on polytopical therapy, clinical features are altered so dependency on microbiological investigation is more by the time cases reached to the referred hospital. The present study aimed to overview the profile of microbial investigation in microbial corneal ulcer cases that were already on polytherapy referred to the ophthalmic department of tertiary care center.

Materials and Methods:
This is a retrospective hospital record-based study where microbiological reports of 58 infective keratitis cases of moderate-to-severe nature were analyzed. Statistical analysis was calculated with confidence intervals (CIs) using “Medcalc” statistical software online.

Results:
Following are the results of the study: 52% patients were males; 18.97% cases were positive for Gram stain. Aerobic culture was positive in 10.34%; potassium hydroxide (KOH) mount was positive in 9.62% cases; sabouraud dextrose agar culture was positive in 7.69% cases. Sensitivity of Gram stain was 33.3% (95% CI: 4.33%–77.72%), whereas specificity was 82.7% (95% CI: 69.67%–91.77%); positive predictive value (PPV) was 18.18% (95% CI: 2.28%–51.78%) and negative predictive value (NPV) was 91.49% (95% CI: 79.62%–97.63%). Sensitivity of KOH mount was 25% (95% CI: 0.63%–80.59%), whereas specificity was 91.67% (95% CI: 80.02%–97.68%); PPV was 20.20% (95% CI: 0.51%–71.64%) and NPV was 93.62% (95% CI: 82.46%–98.66%). Pseudomonas aeruginosa and Staphylococcus aureus were the most common bacterial isolates.

Conclusions:
Basic microbiological investigations have a low yield in chronic infectious keratitis cases that are on prior cocktail long-term therapy. Therefore, advanced tests such as polymerase chain reaction, confocal microscopy, and corneal biopsy may be helpful in managing such challenging cases.
Keratometric Outcomes after Simultaneous versus Sequential Intracorneal Ring Segment Implantation with Femtosecond Laser and Corneal Collagen Crosslinking in Egyptian Patients with Keratoconus and Ectasia
Authors: Nasrat Moataz Mohamed , Abdelsalam Ahmed Medhat , Goily Mohamed Bassam , Eldib Amr A , Hegazy Gehan A 
Published: September 2022

Abstract

Background:
Keratoconus (KC) is degenerative corneal disorder, with central and paracentral thinning and corneal ectasia. For KC progressive cases, primary treatment included corneal collagen cross linking (CXL) to stabilize coning and intracorneal rings segment (ICRS) to correct visual acuity.

Aim:
The aim of the study is to assess efficacy and safety of ICRS and CXL on one session (Simultaneous) or two sessions (sequential) with maximum of 1 month apart.

Patients and Methods:
This Prospective Intervention Comparative research made at Armed forces hospital, Cairo, Egypt from January 2017 to December 2019. Forty patients (60 eyes) with mild to moderate KC were enrolled. Patients sorted into Simultaneous group includes 21 patients (30 eyes) undergo two procedures (ICRS then CXL) at the same session and Sequential group included 19 patients (30 eyes) undergo ICRS then CXL on two sessions with month apart. Patients followed up at end of 1st, 3rd, and 6th months. Assessment included changes in corrected corneal surface irregularities as minimum keratometric 1 (K1), maximum keratometric readings (K2), and mean keratometric (Km) readings.

Results:
Improvement of K1, K2, and Km in Simulations and Sequential groups achieved at end of 1st-, 3rd-, and 6th-month postoperative versus preoperative. Maximum improvement in Simulations and Sequential groups in K1 achieved at end of 6th and 1st months, in K2 at end of 3rd and 6th months and in Km at end of 1st and 3rd months.

Conclusions:
Combined ICRS and CXL act safely in one or two sessions and there are no statistically significant variations between results on both methods in keratometric readings.
Bacteriological Studies of Venomous Snakebite Wounds in Hangzhou, Southeast China
Authors: Hu Sipin , Lou Zhengqing , Shen Yuchen , Tu Mengyun 
Published: September 2022

ABSTRACT.
Snakebite is a common occurrence in Hangzhou, and identifying bacteria in wounds is very important for snakebite treatment. To define the pattern of wound bacterial flora of venomous snakebites and their susceptibility to common antibiotics, we reviewed the medical charts of patients admitted with snakebite at Hangzhou TCM Hospital from January 2019 to December 2020. A total of 311 patients were enrolled in this study. Among them, bacteria culture was positive in 40 patients, and 80 organisms were isolated. The most frequent pathogens were Morganella morganii and Staphylococcus aureus. According to the results of susceptibility testing, a majority of the isolates were resistant to some common first-line antibiotics, such as ampicillin, ampicillin/sulbactam, amoxicillin/clavulanic acid, cefoxitin, and cephazolin. Quinolones, however, have shown a better antibacterial effect. In conclusion, snakebite wounds involve a wide range of bacteria. Fluoroquinolones, such as levofloxacin and ciprofloxacin, could be an alternative for empirical treatment in patients with snakebite when the effect of other antibiotics is poor.
Malaria Control, Elimination, and Prevention as Components of Health Security: A Review
Authors: Perera Ruwanthi , Wickremasinghe Rajitha , Newby Gretchen , Caldera Amandhi , Fernando Deepika , Mendis Kamini 
Published: September 2022

ABSTRACT.
International travel, a major risk factor for imported malaria, has emerged as an important challenge in sustaining malaria elimination and prevention of its reestablishment. To make travel and trade safe, the WHO adopted the International Health Regulations (IHR) which provides a legal framework for the prevention, detection, and containment of public health risks at source. We conducted a systematic review to assess the relevance and the extent of implementation of IHR practices that can play a role in reducing malaria transmission. Selected studies addressed control, elimination, and prevention of reestablishment of malaria. Study themes focused on appraisal of surveillance and response, updating national policies to facilitate malaria control and elimination, travel as a risk factor for malaria and risk mitigation methods, vector control, transfusion malaria, competing interests, malaria in border areas, and other challenges posed by emerging communicable diseases on malaria control and elimination efforts. Review results indicate that malaria has not been prioritized as part of the IHR nor has the IHR focused on vector-borne diseases such as malaria. The IHR framework in its current format can be applied to malaria and other vector-borne diseases to strengthen surveillance and response, overcome challenges at borders, and improve data sharing—especially among countries moving toward elimination—but additional guidelines are required. Application of the IHR in countries in the malaria control phase may not be effective until the disease burden is brought down to elimination levels. Considering existing global elimination goals, the application of IHR for malaria should be urgently reviewed and included as part of the IHR.
PERAN DINAS KOTA SERANG DALAM PEMELIHARAAN ANAK TERLANTAR TAHUN 2021
Authors: Setiyoko Aji Bagus , Basri Alamsyah , Sa’diyah Ade Millatus , Mahmud Toni Anwar , Asmawi Muhamad 
Published: September 2022

ABSRACT
The Serang City Social Service is one of the government affairs assistance agencies of Serang City which carries out its duties in the social sector. One of his duties is the care of neglected children, which is stated in the 1945 Constitution Article 34 Paragraph 1 which explains that the poor and neglected children are cared for by the state. This study aims to determine the extent to which the maintenance of neglected children is carried out by the city government through the Serang City Social Service in 2021. The method used in this study is a qualitative research where the results of the findings in this study will be analyzed and described in detail and clearly. The year 2021 is a very limited year, both in terms of budget, facilities, and direct implementation. PPKM policies issued by the government have had many impacts on existing government elements and the Serang City Social Service is no exception which has experienced many obstacles in the care of neglected children so that in carrying out its role as an authorized institution in the care of abandoned children it does not run optimally.
PERTANGGUNGJAWABAN NOTARIS TERHADAP PEMBATALAN AKTA PERJANJIAN PERKAWINAN BERDASARKAN UNDANG-UNDANG NOMOR 1 TAHUN 1974 TENTANG PERKAWINAN
Authors: Safira Elisa , Salam Abdul 
Published: September 2022

Abstract
In practice, the marriage agreement deed made by a notary can be cancelled by the court. The cancellation causes losses for the party who made it. So it becomes a problem how the notary's responsibility for the cancellation of the marriage agreement deed made in the form of a notary deed carried out by the court. This study aims to analyse the notary's responsibility for cancelling the marriage agreement deed made by the court. The research method used is normative juridical research using a statutory approach and a case approach. The results showed that the notary's responsibility for the marriage agreement deed was cancelled by the court's decision, especially in case number 598 PK/PDT/2016, providing information because the case was included in the administrative area.Furthermore, in the Law on Notary Positions, the notary's responsibility to the deed he makes is that the notary's responsibility is charged to his position. So the result is that the marriage agreement in case Number 598 PK/PDT/2016 is null and void because it does not meet the requirements in Article 29 paragraph (1) of the Marriage Law Article 147 of the Civil Code, namely the marriage agreement, must be made before or when the marriage takes place and is made in a notary deed and ratified by the marriage registrar. Concerning the cancellation of the marriage agreement, it returns to its original state as did not occur in the previous agreement, namely the merger of assets during the marriage and its distribution. Notaries, as public officials, can be held accountable for authentic deeds, resulting in null and void that they make based on the distribution of responsibilities. In this case, the notary's responsibility is borne by the position.
Digitalization of Modules and Learning Tasks for Flexible, Convenient, And Safe Learning Experience of Students
Authors: Culajara Carla Jobelle , Culajara Juan Paolo Martin , Portos Olivia , Villapando Mark Kim 
Published: September 2022

The qualitative research design aims to explore the experiences of Grade 10 students as they were dealing with the new normal of education utilizing a digital modality. This study sheds light on other ways and means of learning and adapting to the modern world using technology. Based on the study's results, five superordinate themes have emerged: flexible, convenient, and safe learning environment, submission challenges, and innovation policy. The digital modality has a substantial impact on the learning of the students. However, they sometimes have difficulty submitting outputs due to a slow internet connection. To reiterate, learning in digital modality is a great help student to in learning capabilities and adapting to change in education and being versatile in learning new different online platforms in simplifying the process and avoiding viruses to spread and becomes safe individual learns and further enhances learning in the modern world of education.
Istibdal Waqf Relevance on Development of Waqf in Indonesia
Authors: Hariyanto Hariyanto , Zaki Irham 
Published: September 2022

<p><em>This study aims to describe madzhab Hambali’s perspective on waqf istibdal, in which there are many opinions among the scholars regarding the ability to implement istibdal on waqf goods. The differences of opinion among fiqh scholars in responding to the dynamics of waqf, the laws related to waqf and their management procedures are important to discuss, because they will have an impact on the formulation of policies that will be taken in the future. And discuss about waqf istibdal relevance on development of waqf in Indonesia by madzhab Hambali’s perspective. This research uses descriptive-qualitative research with the library research method. The results of this study indicate that waqf istibdal is allowed in the perspective of madzhab Hambali and it is very relevant to the development of waqf in Indonesia.</em></p><p><em> </em></p><p><strong><em>Keywords: </em></strong><em>Waqf, Istibdāl, the Development, Madzhab Syafi’i.</em></p>
Financial Exclusion in Northern Nigeria: A Lesson From the Developed Countries
Authors: Muhammad Tijjani , Ngah Besar Bin , Obad Al-Shaghdari Fahd Mohammed 
Published: September 2022

<p>The objective of this paper is to assess the causes of financial exclusion in northern Nigeria, including the reason and causes behind the accessibility to banking services at a competitive and affordable prices. The study adopted Confirmatory Factor Analysis under Structural Equation Modeling using vulnerable group theory (Religiosity and Poverty) and financial literacy theory (Awareness). In this study, the survey method was used, additionally, the stratified sampling technique is applied as it provides richness and accuracy of information from respondents from various stratums. The participants comprised senior, middle and lower classes for the study justification. The finding indicates the positive relationship between Vulnerable Group Theory and Financial Exclusion while Financial Literacy Theory has no relationship as indicated. Therefore, the vulnerability which is consists of Religiosity and Poverty drive as the major causes of Financial Exclusion in Nigeria. The research provided insights and developed a model that indicates the causes of financial exclusion and apparent barriers to better financial services and inclusion in the community and society. This study's originality shows that have not used such vulnerable group theory and financial literacy theory for justification.</p>
Analisis Kualitas Pelayanan Perizinan pada Dinas Penanaman Modal dan Pelayanan Terpadu Satu Pintu Kota Medan
Authors: Arif Muhammad , Wahyudi Ilham 
Published: September 2022

This study aims to describe and analyze the Quality of Licensing Services at the Medan City Investment and One-Stop Integrated Service Office. In this study to collect data the author uses library research methods (Library Research). This technique aims to strengthen the facts in comparing the differences or similarities between theory and practice that the author is researching regarding the problem of “Analysis of the Quality of Licensing Services at the Medan City Investment and One Stop Integrated Service Office”. The results showed that the quality of licensing services at the Medan City DPMPTSP was not maximized and needed improvement, seen from the efforts to improve the quality of services regarding ease of access that were still not maximized due to lack of socialization to the community, and the punctuality of completing the permit letter. Suggestions from this research are to further improve the quality of licensing services regarding completion time in terms of completing permits on time and evaluating the performance of all employees in providing licensing services to the public.
Keywords: Quality, Service, Licensing
Pengaruh Kualitas Pelayanan terhadap Kepuasan Penumpang Maskapai Penerbangan Batik Air di Yogyakarta International Airport Proposal Penelitian
Authors: Arifiyanti Ananda Putri Nadiya 
Published: September 2022

This study focuses on the impact of service quality on the satisfaction of Batik Air passengers at Yogyakarta International Airport. The purpose of this study was to determine the impact and impact of service quality on passenger satisfaction. The method used is a quantitative method, which means using a calculation technique to determine the influence between the service quality of Batik Air airlines. Survey data is in the form of numbers and the analysis uses statistics, so this method is known as the quantitative or positivist method. Used to study a particular population or sample, the data sampling technique is carried out using a targeted sampling approach and is intended to test the proposed hypothesis using a research Data analysis is quantitative. The results showed that the significant value was P : 0.000, which means it is smaller than the 0.05 significance level (α). This means that passenger satisfaction at Batik Air in Indonesia has a great influence between Yogyakarta International Airport services.
Keywords: service quality, pre-flight and passenger satisfaction
Pengaruh Kualitas Layanan Terhadap Loyalitas Pelanggan Pada Maskapai Lion Air di Bandar Udara Internasional El Tari Kupang
Authors: Marselina Andriyani Odem Gerda , Nur Wakhidah Esti 
Published: September 2022

Lion Air is one of many other airlines operating at El Tari International Airport in Kupang. This airline is in great demand by people in the city of Kupang because the fares are quite low and affordable for people from the middle class. This research aims to determine how much influence the quality of service (tangibles, reliability, responsiveness, assurance, empathy) has on customer loyalty. This study uses a quantitative approach with data collection carried out on 5 – 30 October 2021 by distributing questionnaires to Lion Air customers. Analysis of the data method used using Multiple Linear Regression Analysis with the aim of knowing the effect of one or more independent variables on the dependent variable. This research was conducted by distributing a survey to 100 customers who have used the services of Lion Air at El Tari Kupang International Airport. The results of the study show that (1) the tangibles variable is not significantly related to customer loyalty, (2) reliability is significantly related to customer loyalty, (3) responsiveness is not significantly related to customer loyalty, (4) assurance is not significantly related on customer loyalty, (5) empathy has a significant effect on customer loyalty, (6) simultaneously significant values ​​of tangibles (X1), reliability (X2), responsiveness (X3), assurance (X4) empathy (X5) variables affect customer satisfaction (Y) is 0.00 < 0.05 and the calculated F value is 19.625 > F table 2.31, so together or simultaneously have a significant effect on customer loyalty.
Keywords: Service Quality, Customer Loyalty