bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cross-cultural measurement invariance of the Quality of Life Enjoyment and Satisfaction Questionnaire-Short form across ten countries: the application of Bayesian approximate measurement invariance
Authors: Bagheri Zahra , Chamanpara Parisa , Jafari Peyman , Balhara Yatan Pal Singh , Arya Sidharth , Ransing Ramdas , Đorić Ana , Knez Rajna , Thi Tuong-Vi Vu , Huong Truong Ngoc , Kafali Helin Yilmaz , Erzin Gamze , Vally Zahir , Chowdhury Mita Rani Roy , Sharma Pawan , Shakya Rabi , Campos Luís Antônio Monteiro , Szczegielniak Anna Rebeka , Stevanović Dejan 
Published: June 2022

Abstract
Background
The Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form (Q-LES-Q-SF) is the most frequently used generic quality of life (QOL) measure in many countries and cultures worldwide. However, no single study has been carried out to investigate whether this questionnaire performs similarly across diverse cultures/countries. Accordingly, this study aimed to assess the cross-cultural measurement invariance of the Q-LES-Q-SF across ten different countries.

Methods
The Q-LES-Q-SF was administrated to a sample of 2822 university students from ten countries: Bangladesh, Brazil, Croatia, India, Nepal, Poland, Serbia, Turkey, the United Arab Emirates, and Vietnam. The Bayesian approximate measurement invariance approach was used to assess the measurement invariance of the Q-LES-Q-SF.

Results
Approximate measurement invariance did not hold across the countries for the Q-LES-Q-SF, with only two out of 14 items being non-invariant; namely items related to doing household and leisure time activities.

Conclusions
Our findings did not support the cross-cultural measurement invariance of the Q-LES-Q-SF; thus, considerable caution is warranted when comparing QOL scores across different countries with this measure. Item rewording and adaptation along with calibrating non-invariant items may narrow these differences and help researchers to create an invariant questionnaire for reliable and valid QOL comparisons across different countries.
Metadata harmonization–Standards are the key for a better usage of omics data for integrative microbiome analysis
Authors: Cernava Tomislav , Rybakova Daria , Buscot François , Clavel Thomas , McHardy Alice Carolyn , Meyer Fernando , Meyer Folker , Overmann Jörg , Stecher Bärbel , Sessitsch Angela , Schloter Michael , Berg Gabriele ,   The MicrobiomeSupport Team, Arruda Paulo , Bartzanas Thomas , Kostic Tanja , Brennan Paula Iara , Biazotti Bárbara Bort , Champomier-Verges Marie-Christine , Charles Trevor , Coakley Mairead , Cotter Paul , Cowan Don , D’Hondt Kathleen , Ferrocino Ilario , Foterek Kristina , Herrero-Corral Gema , Huitema Carly , Jansson Janet , Liu Shuang-Jiang , Malloy Paula , Maguin Emmanuelle , Markiewicz Lidia , Mcclure Ryan , Moser Andreas , Roovers Jolien , Ryan Matthew , Sarand Inga , Schelkle Bettina , Meisner Annelein , Schurr Ulrich , Selvin Joseph , Tsakalidou Effie , Wagner Martin , Wakelin Steve , Wiczkowski Wiesław , Winkler Hanna , Xiao Juanjuan , Bunthof Christine J. , de Souza Rafael Soares Correa , Sanz Yolanda , Lange Lene , Smidt Hauke 
Published: June 2022

Abstract
Background
Tremendous amounts of data generated from microbiome research studies during the last decades require not only standards for sampling and preparation of omics data but also clear concepts of how the metadata is prepared to ensure re-use for integrative and interdisciplinary microbiome analysis.

Results
In this Commentary, we present our views on the key issues related to the current system for metadata submission in omics research, and propose the development of a global metadata system. Such a system should be easy to use, clearly structured in a hierarchical way, and should be compatible with all existing microbiome data repositories, following common standards for minimal required information and common ontology. Although minimum metadata requirements are essential for microbiome datasets, the immense technological progress requires a flexible system, which will have to be constantly improved and re-thought. While FAIR principles (Findable, Accessible, Interoperable, and Reusable) are already considered, international legal issues on genetic resource and sequence sharing provided by the Convention on Biological Diversity need more awareness and engagement of the scientific community.

Conclusions
The suggested approach for metadata entries would strongly improve retrieving and re-using data as demonstrated in several representative use cases. These integrative analyses, in turn, would further advance the potential of microbiome research for novel scientific discoveries and the development of microbiome-derived products.
Risk factors of anaemia among postpartum women in Bolgatanga Municipality, Ghana
Authors: Wemakor Anthony , Ziyaaba Alice , Yiripuo Felix 
Published: June 2022

AbstractIntroductionAnaemia is a major public health problem affecting women of reproductive age globally. This study was conducted to assess the prevalence and determinants of anaemia among postpartum women in Bolgatanga Municipality, Ghana.MethodsThe study employed an analytical cross-sectional study design to recruit 405 women who delivered in the last 6 weeks from 9 health facilities in the Municipality. Data were collected on socio-demographic characteristics, obstetric characteristics, dietary diversity, knowledge on iron-folic acid (IFA), iron and anaemia, and haemoglobin level of the women. Postpartum anaemia (PPA) was defined as hemoglobin < 12 g/dl. Chi-square and logistic regression analysis were used to identify the determinants of PPA.ResultsThe mean age of the participants was 27.4 ± 5.3 years and 46.70% of them had PPA. The risk factors of PPA were not meeting dietary diversity [Adjusted Odds Ratio (AOR) = 2.96; 95% Confidence Interval (CI): 1.67–5.25], low knowledge on IFA, iron and anaemia (AOR = 3.03; 95% CI: 1.67–5.25), and first trimester pregnancy anaemia (AOR = 10.39; 95% CI: 1.32–6.95). Kusasi ethnicity was protective of PPA (AOR = 0.35; CI: 0.16–0.75).Conclusion:Anaemia is prevalent in postpartum women in Bolgatanga Municipality and its risk factors are dietary diversity, knowledge on IFA, iron and anaemia, pregnancy anaemia and ethnicity. Nutrition counselling and intervention in pregnancy and after delivery are warranted to reduce the burden of anaemia in this population.
Does communication increase investors’ trading frequency? Evidence from a Chinese social trading platform
Authors: Jin Xuejun , Yu Jiawei 
Published: June 2022

AbstractThis study examines the impact of communication on investors’ trading frequency based on a unique dataset drawn from a Chinese social trading platform. We find robust evidence that real-account portfolio owners on the platform trade more frequently under the influence of the comments posted by their leaders (the owners of portfolios they have followed). Moreover, portfolio owners are more sensitive to the quantity than to the tone of leaders’ comments. Finally, both trading frequency and leaders’ comments negatively impact portfolio owners’ future performance. Our findings support the notion that social interaction promotes active investment strategies.
Literature review on earthen vernacular heritage: contributions to a referential framework
Authors: Carlos Gilberto , Ribeiro Telma , Achenza Maddalena , de Oliveira Cristina Cruz Ferreira , Varum Humberto 
Published: June 2022

AbstractThe state of the art of earthen architecture and vernacular built heritage comprises a complex set of issues that range from fundamental problematic recognition to anthropological and cultural studies and, more recently, to technological and experimental analyses. This paper addresses the development of the field, following the milestones of the international literature and pursuing a reflective-theory approach within a historical framework. It aims to explore the main contributions that have enhanced vernacular heritage and earthen architecture as specific domains, from pioneering public awareness essays to institutional expertise guidelines. Finally, in addition to the literature review process, this paper considers the recent corpus of recommendations from conservation management reference institutions, the updating of the operative problematic of earthen vernacular built heritage, and the relevance of local community involvement in facing increasing challenges.
Generation of functional human oligodendrocytes from dermal fibroblasts by direct lineage conversion
Authors: Tanabe Koji , Nobuta Hiroko , Yang Nan , Ang Cheen Euong , Huie Philip , Jordan Sacha , Oldham Michael C. , Rowitch David H. , Wernig Marius 
Published: June 2022

ABSTRACT
Oligodendrocytes, the myelinating cells of the central nervous system, possess great potential for disease modeling and cell transplantation-based therapies for leukodystrophies. However, caveats to oligodendrocyte differentiation protocols ( Ehrlich et al., 2017; Wang et al., 2013; Douvaras and Fossati, 2015) from human embryonic stem and induced pluripotent stem cells (iPSCs), which include slow and inefficient differentiation, and tumorigenic potential of contaminating undifferentiated pluripotent cells, are major bottlenecks towards their translational utility. Here, we report the rapid generation of human oligodendrocytes by direct lineage conversion of human dermal fibroblasts (HDFs). We show that the combination of the four transcription factors OLIG2, SOX10, ASCL1 and NKX2.2 is sufficient to convert HDFs to induced oligodendrocyte precursor cells (iOPCs). iOPCs resemble human primary and iPSC-derived OPCs based on morphology and transcriptomic analysis. Importantly, iOPCs can differentiate into mature myelinating oligodendrocytes in vitro and in vivo. Finally, iOPCs derived from patients with Pelizaeus Merzbacher disease, a hypomyelinating leukodystrophy caused by mutations in the proteolipid protein 1 (PLP1) gene, showed increased cell death compared with iOPCs from healthy donors. Thus, human iOPCs generated by direct lineage conversion represent an attractive new source for human cell-based disease models and potentially myelinating cell grafts.
Imaging nanoscale nuclear structures with expansion microscopy
Authors: Faulkner Emma L. , Pike Jeremy A. , Densham Ruth M. , Garlick Evelyn , Thomas Steven G. , Neely Robert K. , Morris Joanna R. 
Published: June 2022

ABSTRACT
Commonly applied super-resolution light microscopies have provided insight into subcellular processes at the nanoscale. However, imaging depth, speed, throughput and cost remain significant challenges, limiting the numbers of three-dimensional (3D) nanoscale processes that can be investigated and the number of laboratories able to undertake such analysis. Expansion microscopy (ExM) solves many of these limitations, but its application to imaging nuclear processes has been constrained by concerns of unequal nuclear expansion. Here, we demonstrate the conditions for isotropic expansion of the nucleus at a resolution equal to or better than 120–130 nm (pre-expansion). Using the DNA damage response proteins BRCA1, 53BP1 (also known as TP53BP1) and RAD51 as exemplars, we quantitatively describe the 3D nanoscale organisation of over 50,000 DNA damage response structures. We demonstrate the ability to assess chromatin-regulated events and show the simultaneous assessment of four elements. This study thus demonstrates how ExM can contribute to the investigation of nanoscale nuclear processes.
Knowledge and attitudes regarding HIV/AIDS and its prevention among Ghanaian women
Authors: Laari Jacob Loonin , Alhassan Abdul Rauf 
Published: June 2022

Background: HIV/AIDS is still a major public health issue around the world, especially in Sub-Saharan Africa (SSA), where this has resulted in unquantifiable human suffering, social and cultural disruption, and enormous economic losses. Methods: This study aims to assess women’s knowledge and attitude toward HIV/AIDS and its prevention in Ghana. To perform an analytic cross-sectional study, this study used data (the women in reproductive age 15-49 years dataset) from the Ghana Multiple Indicator Cluster Survey (MICS) 2017/18. Bivariate analysis was done using chi-square and predictor variables were identified using binary logistics regression. Results: This study recorded good HIV knowledge and attitude levels of 81.9% and 10.5%. Factors that predicted only good HIV knowledge levels were ethnicity, and disability status. Also, predictors of only good attitude level were type of residence and marital status. Factors implicated in the prediction of both good knowledge and attitude levels were age, educational status, region of orientation, health insurance status, economic status, and media exposure. Conclusions: This study recorded a good HIV knowledge level among the majority of the women, but recorded most respondents having a poor attitude toward HIV.
The effect of non-pharmacologic strategies on prevention or management of intensive care unit delirium: a systematic review
Authors: Cupka Julie S , Hashemighouchani Haleh , Lipori Jessica , Ruppert Matthew M. , Bhaskar Ria , Ozrazgat-Baslanti Tezcan , Rashidi Parisa , Bihorac Azra 
Published: June 2022

Background: Post-operative delirium is a common complication among adult patients in the intensive care unit. Current literature does not support the use of pharmacologic measures to manage this condition, and several studies explore the potential for the use of non-pharmacologic methods such as early mobility plans or environmental modifications. The aim of this systematic review is to examine and report on recently available literature evaluating the relationship between non-pharmacologic management strategies and the reduction of delirium in the intensive care unit. Methods: Six major research databases were systematically searched for articles analyzing the efficacy of non-pharmacologic delirium interventions in the past five years. Search results were restricted to adult human patients aged 18 years or older in the intensive care unit setting, excluding terminally ill subjects and withdrawal-related delirium. Following title, abstract, and full text review, 27 articles fulfilled the inclusion criteria and are included in this report. Results: The 27 reviewed articles consist of 12 interventions with a single-component investigational approach, and 15 with multi-component bundled protocols. Delirium incidence was the most commonly assessed outcome followed by duration. Family visitation was the most effective individual intervention while mobility interventions were the least effective. Two of the three family studies significantly reduced delirium incidence, while one in five mobility studies did the same. Multi-component bundle approaches were the most effective of all; of the reviewed studies, eight of 11 bundles significantly improved delirium incidence and seven of eight bundles decreased the duration of delirium. Conclusions: Multi-component, bundled interventions were more effective at managing intensive care unit delirium than those utilizing an approach with a single interventional element. Although better management of this condition suggests a decrease in resource burden and improvement in patient outcomes, comparative research should be performed to identify the importance of specific bundle elements.
The development of a four-tier test to evaluate training in responsible conduct of research
Authors: Zollitsch Linda , Wilder Nicolaus , Priess-Buchheit Julia 
Published: June 2022

Although higher education institutions across Europe and beyond are paying more and more attention to research integrity (RI) and responsible conduct of research (RCR) training, there are few studies and little evidence on what works and what does not work in these training sessions. One way to overcome this challenge is to evaluate such training with standardised instruments. Experts and trainers have used qualitative approaches to evaluate their training's successes, but it is difficult to compare their results with others. Sometimes they conduct standardised tests drawn from ethics education or other related fields, but these tests do not assess core themes of research integrity as outlined in the European Code of Conduct for Research Integrity (ECoC, 2017). At present, there is a lack of available standardised instruments designed to specifically evaluate success in this training. This article presents a pre-validated instrument for this purpose. The P2I questionnaire is a four-tier test based on the European Code of Conduct for Research Integrity. In it, testees choose a practice in line with research integrity to address an issue, justify their choice, and describe how confident they are with their answers. The development of the P2I questionnaire is outlined in three steps. First we describe the status quo and gaps in evaluating training success, then we illustrate how we designed the P2I questionnaire using practices and justifications in line (and not in line) with research integrity. In the third step, this P2I questionnaire is pre-validated and revised. This questionnaire is a first attempt to engage in a discourse on standardised research integrity instruments and is one step towards an evidence-based improvement of training sessions.
GLIDE Wellcome Open Research Gateway
Authors: Kahn Jeffrey , Ali Joseph , Kingori Patricia , Merritt Maria , Murray Claire , Parker Michael 
Published: June 2022

The Global Infectious Disease Ethics (GLIDE) Collaborative is launching a new Wellcome Open Research (WOR) Gateway, and we as the leaders of GLIDE hope to encourage submissions to this timely and necessary new platform for publishing open access peer-reviewed articles focusing on this area.
PENSAMENTOS INCONSCIENTES COMO BASE DE EXPLICAÇÃO DA CONSCIÊNCIA ENQUANTO PROPRIEDADE DE ESTADOS MENTAIS
Authors: De Athayde Prata Tárik 
Published: June 2022

O artigo aborda a Teoria dos ‘Pensamentos de Ordem Superior’ – a teoria HOT –, proposta por David Rosenthal para explicar a consciência como propriedade de estados mentais, focando a discussão no fato de os pensamentos meta-psicológicos – concebidos por Rosenthal como base de explicação da consciência – são, de acordo com a teoria, pensamentos inconscientes. Após uma exposição dessa teoria (seção 2), será discutido o problema do regresso ao infinito, que é um dos motivos que leva Rosenthal a defender que os pensamentos meta-psicológicos, normalmente, são inconscientes (seção 3), e a argumentação dele a favor dessa inconsciência (seção 4). A conclusão é que, diante do fato de que estados mentais inconscientes são – cotidianamente – capazes de nos tornar cientes de objetos e estados de coisas – apesar de serem inconscientes – mostra que pensamentos meta-psicológicos inconscientes são um candidato promissor a serem a base de explicação da consciência como característica de estados mentais (seção 5).
Palavras-chave: Teoria HOT, Pensamentos meta-psicológicos, Consciência, Inconsciente, Regresso ao infinito.
High-speed long-distance visible light communication based on multicolor series connection micro-LEDs and wavelength division multiplexing
Authors: Zhu Shijie , Qiu Pengjiang , Shan Xinyi , Lin Runze , Wang Zhou , Jin Zuxin , Cui Xugao , Zhang Guoqi , Tian Pengfei 
Published: June 2022

Multicolor series connection micro-LED arrays with emission wavelengths of violet, blue, green, and yellow were fabricated, and their optoelectronic properties and communication performances were investigated. The designed series connection micro-LED array exhibited the light output power of multiple milliwatts, whereas mostly keeping a slightly reduced modulation bandwidth, thus, enabling a higher signal-to-noise ratio compared to a single pixel and showing superior performance in the field of long-distance visible light communication (VLC). The achievable data rates of 400-, 451-, 509-, and 556-nm micro-LED arrays using bit/power loading orthogonal frequency division multiplexing were 5.71, 4.86, 4.39, and 0.82 Gbps, respectively. The aggregate data rate of 15.78 Gbps was achieved for the proof-of-concept wavelength division multiplexing system under a transmission distance of 13 m, which was the best data rate-distance product performance for the LED-based VLC to the best of our knowledge. In addition, the long-distance VLC based on yellow micro-LED was also demonstrated for the first time in this paper.
Determinants of obstructed labour and its adverse outcomes among women who gave birth in Hawassa University referral Hospital: A case-control study
Authors: Desta Melaku , Mekonen Zenebe , Alemu Addisu Alehegn , Demelash Minychil , Getaneh Temesgen , Bazezew Yibelu , Kassa Getachew Mullu , Wakgari Negash 
Published: June 2022

Background
Globally, obstructed labour accounted for 22% of maternal morbidities and up to 70% of perinatal deaths. It is one of the most common preventable causes of maternal and perinatal mortality in low-income countries. However, there are limited studies on the determinants of obstructed labor in Ethiopia. Therefore, this study was conducted to assess determinants and outcomes of obstructed labor among women who gave birth in Hawassa University Hospital, Ethiopia.

Methods
A hospital-based case-control study design was conducted in Hawassa University Hospital among 468 women. All women who were diagnosed with obstructed labour and two consecutive controls giving birth on the same day were enrolled in this study. A pretested data extraction tool was used for data collection from the patient charts. Multivariable logistic regression was employed to identify determinants of obstructed labor.

Results
A total of 156 cases and 312 controls were included with an overall response rate of 96.3%. Women who were primipara [AOR 0.19; 95% CI 0.07, 0.52] and multigravida [AOR 0.17; 95% CI 0.07, 0.41] had lower odds of obstructed labour. While contracted pelvis [AOR 3.98; 95% CI 1.68, 9.42], no partograph utilization [AOR 5.19; 95% CI 1.98, 13.6], duration of labour above 24 hours [AOR 7.61; 95% CI 2.98, 19.8] and estimated distance of 10 to 50 kilometers from the hospital [AOR 3.89; 95% CI 1.14, 13.3] had higher odds. Higher percentage of maternal (65.2%) and perinatal (60%) complications occurred among cases (p-value < 0.05). Obstructed labour accounted for 8.3% of maternal deaths and 39.7% of stillbirth. Uterine rupture, post-partum haemorrhage and sepsis were the common adverse outcomes among cases.

Conclusion
Parity, contracted pelvis, non-partograph utilization, longer duration of labour and longer distance from health facilities were determinants of obstructed labour. Maternal and perinatal morbidity and mortality due to obstructed labour are higher. Therefore, improvement of partograph utilization to identify complications early, birth preparedness, complication readiness and provision of timely interventions are recommended to prevent such complications.