bluuebunny/crossref_metadata_2025_split huggingface dataset:
Contributions of Structural Racism to the Food Environment: A Photovoice Study of Black Residents With Hypertension in Baltimore, MD
Authors: Hines Anika L. , Brody Rebecca , Zhou Zehui , Collins Sarah V. , Omenyi Chiazam , Miller Edgar R. , Cooper Lisa A. , Crews Deidra C. 
Published: November 2022

Background:
Disproportionate exposure to poor food environments and food insecurity among Black Americans may partially explain critical chronic disease disparities by race and ethnicity. A complex set of structural factors and interactions between Black residents and their food environments, including store types, quantity, proximity, and quality of goods and consumer interactions within stores, may affect nutritional behaviors and contribute to higher cardiovascular and kidney disease risk.

Methods:
We used the Photovoice methodology to explore the food environment in Baltimore, MD, through the perspectives of Black residents with hypertension between August and November 2019. Twenty-four participants were enrolled in the study (mean age: 65.1 years; 67% female). After a brief photography training, participants captured photos of their food environment, which they discussed in small focus groups over the course of 5 weeks. Discussions were audiotaped and analyzed for emergent themes using a line-by-line inductive approach. Themes were, then, organized into a collective narrative.

Results:
Findings describe physical and social features of the food environment as well as participants’ perceptions of its origins and holistic and generational health effects. The study illustrates the interrelationships among the broader socio-political environment, the quality and quantity of stores in the food landscape, and the ways in which they engage with the food environment as residents and consumers who have been marginalized due to their race and/or social class. The following meta-themes emerged from the data: (1) social injustice; (2) structural racism and classism; (3) interpersonal racism; (4) generational effects; (5) mistrust; (6) social programs; and (7) community asset-based approaches, including advocacy and civic engagement.

Conclusions:
Understanding residents’ perceptions of the foundations and effects of the food environment on their health may help stakeholders to cocreate multilevel interventions alongside residents to improve access to healthy food and health outcomes among disparities affected populations.
The Performance of Blessing as Imitation of Divine Beings
Authors: Bakker Arjen 
Published: November 2022

Abstract
This essay examines Qumran texts that not only perform blessing but also reflect on the activity of blessing itself, and thereby offer an opportunity to better understand the urge and necessity behind the growth of liturgical cycles that generate traditions of prayer. The paper looks at three texts, the hymns of the maśkîl, the Hymn to the Creator, and 4Q408, in which the performance of blessing is presented as acknowledgment of the creator through the lens of primordial time and the actualization of creation narratives. The essay argues that the way in which divine beings are imagined as perceiving and responding to the act of creation forms a model that liturgical performers emulate in order to approach as much as possible the holiness of these higher beings. This example demonstrates the interaction between interpretation and performance and their impact on the emergence and growth of textual traditions, both oral and written, in the Second Temple period.
When the Readers Break the Rules
Authors: van Putten Marijn 
Published: November 2022

Abstract
The Quranic text today is recited in ten canonical reading traditions with two distinct canonical transmissions each. These reading traditions are distinct in their phonological and morphological details, as well as the interpretation of the ambiguous consonantal text. However, they all have in common that they adhere to the consonantal skeleton of the standard Quran text. Despite this adherence, on rare occasions readers do deviate from this standard text. This paper examines those cases, and explores the reasons why the canonical readers felt licensed to do so. Especially ʾAbū ʿAmr was prone to deviate from the consonantal text in cases of perceived grammatical issues. Moreover, the readers occasionally deviated from their regional consonantal text when other regional codices had another form. Finally, readers deviated from the consonantal text, in cases where the text came in conflict with the pausal spelling principle.
Hymns and the Singing Community: The Formation of the Canaan Hymns in Contemporary Chinese Churches
Authors: Xu Songzan , Yang Xiaoli 
Published: November 2022

Abstract
This article studies the formation of the Canaan Hymns (Jianan shige 迦南诗歌) in relation to the history of the contemporary Chinese indigenous church. Over the last thirty years, Lü Xiaomin (吕小敏, 1970–) has composed more than two thousand hymns. They reflect not only her own personal life and evangelism, but also the growth of the Fangcheng Fellowship (方城团契) in Henan Province from a local home gathering to a national mission movement. Through textual studies, interviews, and archival research, this article examines how local congregants adopted Lü’s hymns, which are distinct from both western traditional hymns and Chinese rural spiritual songs (lingge 灵歌). These hymns represent a unique form of theological meaning-making within the indigenous church movement and serve as a pointer to the Chinese understanding of missio Dei as a whole.
Toward a Chinese Buddhist Modernism: Khenpo Sodargye and the Han Inundation of Larung Gar
Authors: Taylor (唐安竺) Andrew S. 
Published: November 2022

Abstract
Larung Gar is often hailed by scholars and practitioners alike as a last bastion of authentic Buddhist practice by ethnic Tibetans within the PRC. And yet, Larung is visited every year by tens of thousands of Han pilgrims and houses hundreds of Han monastics who have taken vows in the Tibetan Buddhist tradition. The author draws on a variety of oral and written sources to show that the Han inundation of Larung was not a byproduct of happenstance, but was actively facilitated by the Larung leadership, especially Khenpo Sodargye (མཁན་པོ་བསོད་དར་རྒྱས་ 索达吉堪布), through the targeted recruitment of Han practitioners. A comparative analysis of Tibetan- and Chinese-language materials shows that the neo-scientific and therapeutic teachings used to recruit Han practitioners superficially resemble similar “Buddhist modernist” discourses in the west and Tibet, but that their content is decidedly more soteriological than this moniker suggests. The article considers whether the encounter between Han practitioners and Tibetan Buddhism might eventually represent a nascent form of inter-ethnic Chinese Buddhist modernism.
Multidecadal Fluctuations of SST and Euphotic Zone Temperature off Northwest Africa
Authors: Ibrahim Hamed D. , Sun Yunfang 
Published: November 2022

Abstract
The Atlantic multidecadal variability (AMV) switched from a cool to a warm phase in 1995 and the mean euphotic zone (EZT) and sea surface temperature (SST) shifted upward by 0.57° and 0.69°C, respectively, between 1982–91 and 2006–15 in the Atlantic region off northwest Africa. This ocean margin has many marine fisheries, and water temperature fluctuations may cause fish there to switch their habitats. Net radiation flux did not significantly change between these two decades. So, we hypothesized that the key driver of the EZT and SST increase is wind, which controls turbulent (sensible and latent) heat exchange with the atmosphere as well as bulk vertical and horizontal heat transport. Using satellite-derived SST and atmospheric and oceanic reanalyses to analyze the ocean top-200-m heat budget, we compared the relative contributions of the heat budget components to the cyclical changes in EZT and SST between these two decades. Results showed that the dominant heat source is horizontal heat flux convergence: weaker northeasterly trades and stronger southerly winds and monsoon enabled the southerly winds to drive warm water northward that subsequently warmed the domain. The dominant heat sink is latent heat loss: onshore–offshore atmospheric pressure gradients caused a complex wind adjustment that enabled the Sahara wind to accelerate evaporation over large subregions. These results highlight the important roles of ocean heat transport and atmosphere–ocean coupling for the tropical branch of the AMV. The regional EZT and SST anomalies associated with this AMV phase switch are mainly a consequence of wind-driven processes occurring at larger spatial scales.
Anterior and Lateral Skull Base Spontaneous CSF Leaks: Evaluation of Comorbidities and Treatment Outcomes
Authors: Hentati Firas , Kocharyan Armine , Ruthberg Jeremy , Trudeau Stephen , Jella Tarun , Patil Nirav , Cabrera Claudia I. , Mowry Sarah E. 
Published: November 2022

Objectives: To evaluate clinical characteristics and outcomes of patients diagnosed with anterior (ASB) or lateral skull base (LSB) spontaneous cerebrospinal fluid (sCSF) leak. Methods: Single center retrospective review of patients diagnosed with sCSF leaks of ASB or LSB between 1/1/2009 and 11/1/2019 (n = 69). Body mass index (BMI), gender, age at diagnosis, origin of CSF leak (ASB vs LSB), surgical approach, lumbar drain use, recurrence, pre-operative diagnosis of diabetes mellitus (DM), and obstructive sleep apnea (OSA) were collected. Results: 69 patients included in this study met criteria for sCSF leak without a traumatic or iatrogenic cause (Female: 51 (74%); average BMI: 37.0 ± 7.9). Forty-eight (70.0%) presented with sCSF leaks of the lateral skull base. All ASB leaks were treated with an endoscopic transnasal approach. Eleven (22.9%) LSB leak patients were treated using transmastoid approaches and 35 (72.9%) patients with a middle cranial fossa approach. Eleven patients (15.9%) reported sCSF leak recurrence. Two patients (9.5%) with anterior skull base and 9 patients (18.8%) with lateral skull base leaks had recurrence. LSB sCSF leaks had a relative risk of 2.192 of recurrence compared to ASB leaks (95% CI: 0.431-11.157, P = .483). A 5.017 times increased risk (95% CI: 1.285-19.583, P = .020) was reported for patients with OSA, while the risks for DM and BMI were 1.351 (95% CI: 0.67-9.105, P = .177) and 1.026 (95% CI: 0.963-1.094, P = .426) respectively. Patients with sCSF leak recurrence had significantly lower lumbar drain use (33.3%) than those without recurrence (72.7%) ( P = .049). Conclusion: Spontaneous CSF leak recurrence is complex and multifactorial, and while patients with both DM and OSA had the higher risk of recurrence, OSA is likely an independent clinical risk factor for sCSF leak recurrence in this patient population.
A Retrospective Study to Assess the Accuracy of Frozen Sections in Laser Laryngeal Surgery
Authors: Nerurkar Nupur Kapoor , Shah Keya , Patel Keyuri , Muzumdar Girish 
Published: November 2022

Objective: The basis of good vocal outcomes following Transoral Laser Microlaryngeal Cordectomy (TLMC) is the narrow margin that is oncologically accepted for the glottis. Our objective is to evaluate the reliability of frozen section (FS) compared to paraffin section (PS) during TLMC and during laser laryngeal surgery when an incisonal or excisional biopsy is being performed. Methods: Retrospectively, records of 159 sequential patients who underwent CO2 laser laryngeal surgery with intraoperative FS were reviewed along with the final PS. Group A patients were TLMC patients where FS was utilized for free margin confirmation (42 specimens) and Group B patients were those in whom FS was performed for primary diagnosis (122 specimens). Results: A total of 164 samples were included where specimens submitted for FS were also processed for PS. Concordance was observed in 156 samples, discordance in 8, with 4 cases belonging to each group. FS was reported as false negative in 5 and false positive in 3 cases. In Group A where FS was utilized for free margin confirmation, the sensitivity was found to be 60%, specificity and positive predictive value (PPV) 100%, and negative predictive value (NPV) 88.9%. In Group B where FS was performed for primary diagnosis, the sensitivity was found to be 98.4%, specificity 95.1%, PPV 95.2%, and NPV 98.3%. Conclusion: A 100% PPV of FS in group A suggests that positive FS margins during TLMC may be safely relied upon in making decisions to upgrade the type of cordectomy being performed. A NPV of 88.9% in group A suggests that despite a clear frozen margin report during TLMC, 11.1% of patients would need further treatment. A PPV of 95.2% in group B suggests that although FS analysis is important for guiding further management, decisions regarding major laryngeal surgery should not be undertaken based solely on FS.
Coronavirus–Related Stressors, Resilient Mindset, Loneliness, Depressive Symptoms in College Students: Testing a Moderated Mediation Model
Authors: Arslan Gökmen , Coşkun Muhammet 
Published: November 2022

The coronavirus (COVID-19) outbreak alarmingly threats the mental health and functioning of people globally. The present study aims to examine the moderated mediation role of resilient mindset and loneliness in the association of coronavirus stress and depressive symptoms. We recruited 394 undergraduate students from a state university in Türkiye, ranging in age between 18 and 47 years ( M = 22.76, SD = 3.88; 65% female). The main results revealed that resilient mindset mediated the relationship between coronavirus-related stress and depressive symptoms. Moreover, loneliness moderated the mediating effect of resilient mindset in the coronavirus stress and depressive symptoms association. Taken together, these findings pointed out that the effects of the coronavirus stress on depressive symptoms can be captured better by underlying psychological mechanisms, namely resilient mindset and loneliness.
Diagnostic and predictive value of resistive / pulsatility indices of ophthalmic artery and common carotid artery for the development of diabetic retinopathy
Authors: Şimşek Sadullah , İşlek Akif 
Published: November 2022

Background Ophthalmic artery resistive index (OA RI) was a controversial parameter to show hemodynamic changes due to diabetic retinopathy (DRP). Purpose To investigate the diagnostic and predictive value of resistive and pulsatility index (RI and PI, respectively) of OA and common carotid artery (CCA) for the development of DRP. Material and Methods A total of 60 patients with diabetes mellitus (DM) type 2 (study group) and 30 healthy participants (control group) were evaluated between January and June 2021 by Doppler ultrasonography (DUS). RI and PI values were compared between groups with a Student’s t-test. Cutoff value, sensitivity, and specificity were calculated for the significant variables with receiver operating characteristic (ROC) analysis. Results In total, there were 20 (22.2%) patients with DM without DRP (DMwoRP), 20 (22.2%) patients in the non-proliferative diabetic retinopathy group (NPDRP), and 20 (22.2%) patients in the proliferative diabetic retinopathy group (PDRP). The mean of CCA RI and OA RI in the PDRP group was significantly higher than in the other three groups ( P < 0.001). The mean of CCA RI and OA RI was significantly higher in the PDRP group than in the NPDRP group, and in the NPDRP group compared to the DMwoRP group. CCA RI and OA RI showed a significantly high correlation (r = 0.849; P < 0.001). Sensitivity was 95% and specificity was 100% for the diagnosis of PDRP for the 0.82 cutoff value of OA RI (AUR = 0.999, 95% confidence interval for AUC = 0.997–0.1000; P < 0.001). Conclusion The OA RI accurately reflects DRP-induced orbital blood flow changes and is a predictive index for DRP prognosis.
Plasma metabolomics for the assessment of the progression of non-small cell lung cancer
Authors: Zhang Yingtian , Cheng Yaping , Qin Liqiang , Liu Yuanliang , Huang Sijia , Dai Liya , Tao Jialong , Pan Jie , Su Cunjin , Zhang Yusong 
Published: November 2022

Objectives Non-small cell lung cancer (NSCLC) is a leading type of lung cancer with a high mortality rate worldwide. Although many procedures for the diagnosis and prognosis assessment of lung cancer exist, they are often laborious, expensive, and invasive. This study aimed to develop an ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC–MS/MS)-based analysis method for the plasma biomarkers of NSCLC with the potential to indicate the stages and progression of this malignancy conveniently and reliably. Methods A total of 53 patients with NSCLC in early stages (I–III) and advanced stage (IV) were classified into the early and advanced groups based on the tumor node metastasis staging system. A comprehensive metabolomic analysis of plasma from patients with NSCLC was performed via UPLC–MS/MS. Principal component analysis and partial least squares–discriminant analysis were conducted for statistical analysis. Potential biomarkers were evaluated and screened through receiver operating characteristic analyses and correlation analysis. Main differential metabolic pathways were also identified by utilizing metaboanalyst. Results A total of 129 differential metabolites were detected in accordance with the criteria of VIP ≥ 1 and a P-value of ≤ 0.05. The receiver operating characteristic curves indicated that 11 of these metabolites have the potential to be promising markers of disease progression. Apparent correlated metabolites were also filtered out. Furthermore, the 11 most predominant metabolic pathways with alterations involved in NSCLC were identified. Conclusion Our study focused on the plasma metabolomic changes in patients with NSCLC. These changes may be used for the prediction of the stage and progression of NSCLC. Moreover, we discussed the metabolic pathways wherein the altered metabolites were mainly enriched.
Childhood Small-Vessel Primary Angiitis of the Central Nervous System: Overlap With MOG-Associated Disease
Authors: Gilani Ahmed , Kleinschmidt-DeMasters Bette K. 
Published: November 2022

Background: Childhood (c) primary angiitis of the central nervous system (PACNS) is a rare condition that most often affects small vessels (SV), is nearly exclusively lymphocytic, and devoid of vessel necrosis. Diagnosis of cSV-PACNS is challenging. We noted possible histological overlap of cSV-PACNS with myelin oligodendrocyte glycoprotein disease (MOGAD) on biopsy, prompting a 10-year retrospective review of our experience. Materials and Methods: Database-search for brain biopsy cases, age <18 years, performed for an acquired neurological deficit with suspicion of vasculitis, with histological evidence of lymphocytic small-vessel inflammation. Results: We identified 7 patients; 2/7 were serum-positive for anti-MOG antibodies and 1/7 for anti-NMDA antibodies. The remaining 4/7 proved to be idiopathic lymphocytic vasculitis/cSV-PACNS. All 7 showed overlapping features of lymphocytes permeating parenchymal SV walls, vessel wall distortion without fibrinoid necrosis, and absence of microglial clusters or intravascular thrombi. Tissue infarction was confined to a single case of idiopathic lymphocytic vasculitis. Although demyelination was diligently sought, only subtle demyelination was identified in the 2 MOGAD cases and absent in the remainder. Conclusion: There is considerable histological overlap between cSV-PACNS and at least some cases of MOGAD or anti-NMDA-encephalitis; at diagnosis, the differential should include cSV-PACNS but correct classification requires post-biopsy serological testing.
A transcriptome-Based Deep Neural Network Classifier for Identifying the Site of Origin in Mucinous Cancer
Authors: Ahn Taejin , Kim Kidong , Kim Hyojin , Kim Sarah , Park Sangick , Lee Kyoungbun 
Published: November 2022

Purpose: There is a lack of tools for identifying the site of origin in mucinous cancer. This study aimed to evaluate the performance of a transcriptome-based classifier for identifying the site of origin in mucinous cancer. Materials And Methods: Transcriptomic data of 1878 non-mucinous and 82 mucinous cancer specimens, with 7 sites of origin, namely, the uterine cervix (CESC), colon (COAD), pancreas (PAAD), stomach (STAD), uterine endometrium (UCEC), uterine carcinosarcoma (UCS), and ovary (OV), obtained from The Cancer Genome Atlas, were used as the training and validation sets, respectively. Transcriptomic data of 14 mucinous cancer specimens from a tissue archive were used as the test set. For identifying the site of origin, a set of 100 differentially expressed genes for each site of origin was selected. After removing multiple iterations of the same gene, 427 genes were chosen, and their RNA expression profiles, at each site of origin, were used to train the deep neural network classifier. The performance of the classifier was estimated using the training, validation, and test sets. Results: The accuracy of the model in the training set was 0.998, while that in the validation set was 0.939 (77/82). In the test set which is newly sequenced from a tissue archive, the model showed an accuracy of 0.857 (12/14). t-SNE analysis revealed that samples in the test set were part of the clusters obtained for the training set. Conclusion: Although limited by small sample size, we showed that a transcriptome-based classifier could correctly identify the site of origin of mucinous cancer.
LVIS EVO stent-through-balloon after hydrocoil embolization of intracranial aneurysms: One-year results
Authors: Mosimann Pascal J , Yamac Elif , Wallocha Marta , Ayad Ahmed , Chapot René 
Published: November 2022

Background and purpose To evaluate the durability and safety of complete intracranial aneurysm occlusion at one year using the low-profile braided intracranial LVIS EVO stent. Materials and methods This is a retrospective, monocentric, observational study of unruptured wide-necked intracranial aneurysms treated with the LVIS EVO stent-through-balloon technique after balloon-assisted hydrocoil embolization. Imaging and clinical data were assessed by two blinded independent neuroradiologists and neurologists, respectively. Primary endpoint was complete angiographic occlusion on day 0 and at 12 months. Secondary endpoints included clinical safety using the modified Rankin scale (mRS), ischemic and hemorrhagic adverse events, parent vessel stenosis > 50% or occlusion and retreatment rate. Results 103 aneurysms in 103 patients were included (53 years-old, 77% women). Mean aneurysm size and neck were 7 and 4 mm, respectively. Complete occlusion was 97% initially and 90% at 12 months, with pending follow up in 17.5% patients. Five patients (5%) with partially stented necks were retreated with a second stent in a T-configuration. Two stents failed to open initially and were immediately retrieved. Asymptomatic parent vessel occlusion and severe in-stent stenosis occurred in 1% and 3%, respectively. The 12-month procedure-related permanent neurological deficit and mortality rates (mRS 3–6) were 2% and 1%, respectively. There was one fatal bleeding but no large ischemic complications. Conclusion Delivering the LVIS EVO stent through a dual lumen balloon after balloon-assisted hydrocoil embolization yields a high and stable rate of complete aneurysm occlusion at one year with a reasonable immediate and delayed complication rate.