bluuebunny/crossref_metadata_2025_split huggingface dataset:
Formation of adaptive subscriptions to the Internet of things data broker
Authors: Isaeva Olga , Isaev Sergey , Kulyasov Nikita 
Published: November 2022

Intoduction: the possibility of interaction with the physical world through the network infrastructures of spatially distributed nodes of Internet of Things, despite the undeniable advantages of the technology, produce significant loads on information consumers. In this regard, the current interest is the creation of methods that provide the reduction of transmitted data due to the adaptive synchronization of monitoring systems with the time of real processes. One effective way to solve this problem is to use the discrete Fourier transform to determine the sampling period of the observations. Purpose: to develop an approach to the formation of adaptive data broker subscriptions based on the study of the cyclicity of observations of Internet of Things devices. Methods: the discrete Fourier transform method was applied and, based on the calculated parameters of the harmonic series, a conclusion about the frequency characteristics of the data was made. The main peaks describing the periodicity of the data are selected, the fluctuation points are determined and, according to the Kotelnikov theorem (Nyquist-Kotelnikov-Shannon Sampling Theorem), a sampling frequency that provides a sufficient intensity of observations is chosen. Results: within the corporate network of the Krasnoyarsk Scientific Center, an infrastructure of devices and applications of the Internet of Things has been deployed to monitor temperature, humidity and PM2.5 in specialized technological rooms with telecommunications equipment. The analysis showed that for different rooms the data are periodic, but their harmonic profiles do not coincide. The choice of harmonic values, the fluctuation amplitude of which determines the dynamics of changes in the observed data, should be carried out periodically for each observed device. This approach is implemented in the broker software, which distributes data in subscriptions from each of the devices in accordance with the frequency of their changes. Practical relevance: the analysis of the frequency characteristics of the data determines the broker settings, which distributes the information flows, which is one of the aspects of reliability of the IoT infrastructure.
In addition, observing data changes will allow us to identify malfunctions in the operation of cooling systems, which can lead to the failure of complex, expensive equipment with increased heat irradiation.
STAKEHOLDER’S PERCEPTIONS OF MINING INDUSTRY IN PERU: COMMUNITY INVOLVEMENT IN DECISION-MAKING AND THEIR CAUSAL CONDITIONS
Authors: Garcia-Ortega Beatriz , De-Miguel-Molina Blanca , Chirivella-González Vicente 
Published: November 2022

This paper studies the community involvement in decision-making on CSR investments of mining firms in Peru and its causal conditions through stakeholder’s perceptions. To this end, community members, NGOs and consultants were interviewed. The focus was on various causal conditions in which stakeholders: a) explain the community needs, b) recognize the investments made by the companies, c) believe that mining benefits are not what they expected, d) declare the costs generated by these activities and e) point out that dialogue is the solution. Collected data were processed via a content analysis, followed by a Qualitative Comparative Analysis (QCA). The conditions which appeared in the QCA solutions were different depending on whether the community participated or not in decision-making, with the second situation prevailing. The results offer further understanding to all parties and may help companies to improve their performance.
Legal foundations of the organization and activities of the Ukrainian SSR police in 1949–1950s
Authors: Brusakova О. V. , Hrechenko V. A. 
Published: November 2022

The main aspects of the structure of the police in 1949–1950 and the main directions of its activity have been studied. The changes in the Criminal Procedure Code of the Ukrainian SSR guided by the police in the performance of their law enforcement functions have been highlighted. It has been noted that the structure of local police bodies in the regions of Ukraine in the post-war period was of the same type, but could differ depending on operational conditions in the number of regular units. The most important change in the structure of the Ministry of Internal Affairs during this period was the transfer of the police to the Ministry of State Security in October 1949. The activities of the police were controlled and regulated by decisions and resolutions of the Communist Party of Ukraine. First of all, it concerned the selection of personnel and education of police personnel. The central governing body of the police was the Main Directorate of the Police. The police departments of the Union republics, regions, large cities, district departments and branches, military units of the police were subordinate to it. At the same time, the heads of these police bodies held the positions of deputy people’s commissars of internal affairs of the republics, heads of regional NKVD (People’s Commissary of Internal Affairs) departments, heads of departments and NKVD departments of cities and districts.
The causes of crime in the specified period have been analyzed. Considerable attention has been paid to the work of the police in combating crime, which was carried out in the following areas: 1) prevention and detection of crimes by structural units of the police (criminal investigation and fight against theft of socialist property and speculation); 2) conducting inquiries and performing a number of investigative functions. Factors that did not allow the police to fully perform their functions in the fight against crime were: 1) insufficient use of scientific and technical means; 2) lack of an extensive agent-informant network; 3) lack of professional personnel; 4) violation of “socialist legality” during inquiry and investigation; 5) involvement of operatives of criminal investigation and employees of anti-theft of socialist property and speculation of the BRSVS (the department for combating embezzlement of socialist property and speculation) to perform functions that are not specific to them. The practical activity of police bodies for the protection of public order was determined by the following directions: 1) administrative activity (patrol in populated areas, compliance with the rules of the passport and permit system, regulation of street traffic); 2) involvement of state institutions, public organizations and citizens in cooperation; 3) creation of voluntary formations - police assistance brigades and public order protection groups.
PEMBUATAN POP UP BOOK SARAPAN SEBAGAI MEDIA EDUKASI UNTUK ANAK SEKOLAH DASAR
Authors: Widyawati Agatha , Indana Nadia 
Published: November 2022

Anak sekolah dasar merupakan golongan usia 6-12 tahun yang memasuki masa pertumbuhan dan perkembangan yang memerlukan fisik yang sehat. Apabila anak sekolah dasar kekurangan asupan gizi yang seimbang maka akan mempengaruhi pertumbuhan dan perkembangannya. Salah satu cara untuk memenuhi asupan gizi anak sekolah dasar dengan membiasakan sarapan pagi. Namun, masih banyak anak sekolah dasar yang sering melewatkan sarapan sehingga menyebabkan pusing, sakit perut dan rendahnya konsentrasi. Oleh karena itu perlu adanya pemberitahuan tentang sarapan yang penting untuk dilakukan, sehingga hal ini mendorong peneliti untuk membuat media alternatif melalui media pop up book. Tujuan penelitian ini adalah membuat media pop up book sarapan sebagai edukasi gizi untuk anak sekolah dasar di SDN Mumbulsari 03. Penelitian ini merupakan jenis penelitian Research and Development yang menggunakan model ADDIE (Analysis, Design, Development, Implementation dan Evaluation). Penelitian ini menggunakan instrumen berupa lembar wawancara, kuesioner dan angket. Lembar wawancara dan kuesioner digunakan untuk mengumpulkan informasi dan menentukan masalah serta angket digunakan untuk mengumpulkan informasi terhadap kebutuhan media pop up book. Penelitian pengembangan ini menggunakan teknik analisis data yaitu, teknik analisis data deskriptif kualitatif dan teknik analisis data deskriptif kuantitatif. Data kualitatif berupa kritik dan saran dari validator yang akan dijadikan sebagai bahan perbaikan produk yang dikembangkan. Kesimpulan yang didapatkan menghasilkan media pop up book sarapan untuk anak sekolah dasar sebagai media edukasi gizi. Dan memperoleh penilaian dari ahli materi sebesar 97,5% dengan katogori sangat baik dan tidak perlu direvisi serta ahli media 88,3% dengan kategori baik dan direvisi seperlunya.
Study of Serum Lipid Profile and Aminotransferases (ALT and AST) in Non-obese, Non-diabetic Nonalcoholic Fatty Liver Disease
Authors: Islam ASM Mazedul , Muttalib MA , Islam Md Nazrul , Haque Md Rashedul , Hoque Mohammad Rafiqul , Maknunnahar - 
Published: November 2022

Background: Non-alcoholic fatty liver disease (NAFLD) comprises a spectrum of liver diseases characterized by simple steatosis to nonalcoholic steatohepatitis (NASH), fibrosis, and cirrhosis. It is the most common cause of cryptogenic cirrhosis. NAFLD is associated with obesity, insulin resistance, hypertension, type 2 diabetes mellitus, and dyslipidemia.
Objective: The study aimed to assess the changes in lipid profile and aminotransferases (ALT and AST) in Non-alcoholic fatty liver disease (NAFLD).
Methods: This observational cross-sectional study was carried out in the department of Biochemistry, Mymensingh Medical College in cooperation with the Centre for Nuclear Medicine and Ultrasound, Mymensingh from January 2012 to June 2013 after the approval of the protocol. A total of 120 subjects were included through purposive sampling, among them, 60 subjects were with fatty liver disease (group-I) and another 60 were without fatty liver (group-II) with ultrasonography. The sampling method was purposive (non-random). Relevant laboratory investigations were performed by using established methods to achieve the objectives.
Results: The majority of the subjects with NAFLD (33.33%) were in 51-60 years (in Group-I). Mean serum total cholesterol, triacylglycerol, LDL-cholesterol, and HDL-cholesterol were 203.33±21.83, 184.41±33.31, 126.28±18.75, and 40.17±6.32 mg/dl in group-I and 167.65±9.83, 128.77±11.65, 101.74±9.29 and 40.16±3.55 mg/dl in group-II respectively. Significant differences were found in the case of total cholesterol (p<0.001), triacylglycerol (p<0.001), and LDL-cholesterol (<0.001), but no significant difference was found in the case of HDL-cholesterol (p>0.05). Serum ALT and AST were 49.43±16.98, 45.20±13.56 U/L in group-I and 32.83±4.54, 28.68±4.31 U/L in the group- II respectively. Significant differences were found in case of ALT (p <0.001) and AST (p <0.001).
Conclusion: Nonalcoholic fatty liver disease is associated with dyslipidemia and with the elevation of serum ALT and AST.
J Rang Med Col. September 2022; Vol. 7, No. 2:35-39
Analisis Karakteristik Akun Twitter Berdasarkan Sentimen Pendapat Terkait Undang-Undang PSE
Authors: Rivaldi Arya Akbar , Yudhantorro Bayu Azra , Ziaulhaq Ibadurrahman , Nur Aini Rakhmawati  
Published: November 2022

Aturan untuk penyedia layanan di internet atau Penyelenggara Sistem Elektronik di Indonesia mendapatkan pro dan kontra semenjak adanya Peraturan Pemerintah yang diterbitkan. Twitter sebagai media sosial, menjadi salah satu tempat menyampaikan pendapat secara bebas, tidak terkecuali pendapat untuk peraturan PSE. Penelitian ini bertujuan untuk mengidentifikasi karakteristik akun pengguna Twitter dengan mempertimbangkan sentimen tweet mereka terhadap Peraturan PSE. Analisis ini dilakukan dengan mengidentifikasi sentimen pada data tweet, kemudian melihat atribut dari akun pengguna tweet tersebut. Pada proses penggalian data didapatkan sebanyak 849 tweet, 679 diantaranya diberikan label sentimen yang kemudian akan digunakan untuk membangun model machine learning berbasis IndoBERT. Selanjutnya, sebanyak 335 data terkait akun pengguna yang terikat dengan data tweet diatas juga didapatkan. Model machine learning yang dihasilkan mencapai akurasi sebesar 71%, didapatkan juga model paling baik dalam mengklasifikasi tweet dengan sentiment negatif. Ditemukan bahwa akun yang mendukung PSE atau memiliki postingan tweet dengan sentimen positif berusia lebih muda dibandingkan yang bersentimen negatif. Meski begitu rata-rata jumlah tweet yang dihasilkan akun-akun bersentimen positif lebih banyak dibandingkan akun dengan sentimen negatif meskipun rata-rata usianya jauh lebih tua. Ini menunjukkan bahwa akun bersentimen positif lebih sering mengirim tweet dibandingkan akun bersentimen negatif.
The effect of heat pre-treatment on the anaerobic digestion of high-solid pig manure under high organic loading level
Authors: Li Pengfei , Wang Jianlin , Peng Hao , Li Qichen , Wang Ming , Yan Wencong , Boboua Stopira Yannick Benz , Li Wenzhe , Sun Yong , Zheng Guoxiang , Zhang Hongqiong 
Published: November 2022

Since more and more large-scale farms appear in China and changes in fecal sewage source disposal, the production of high-concentration solid manure waste is also increasing, and its conversion and utilization are gaining attention. This study investigated the effect of heat pre-treatment (HPT) on the thermophilic anaerobic digestion (AD) of high-solid manure (HSM). Pig manure (PM) feed with a total solids of 13% was used for the HPT and subsequent anaerobic digestion (AD) test. The HPT was carried out at 60°C, 80°C, and 100°C, respectively, for 15 min after the heating reached the set temperature. The results show that HPT led to PM feed COD solubilization, observing a maximum increase of 24.57% after pretreated at 100°C, and the treated PM feed under this condition received the maximum methane production potential of 264.64 mL·g−1 VS in batch AD test, which was 28.76% higher than that of the untreated group. Another semi-continuous AD test explored the maximum volume biogas production rate (VBPR). It involves two organic loading rates (OLR) of 13.4 and 17.8 g VSadded·L−1·d−1. The continuous test exhibited that all the HPT groups could produce biogas normally when the OLR increased to the high level, while the digester fed with untreated PM showed failure. The maximum VBPR of 4.71 L L−1·d−1 was observed from PM feed after pre-treated at 100°C and running at the high OLR. This reveals that thermal treatment can weaken the impact of a larger volume of feed on the AD system. Energy balance analysis demonstrates that it is necessary to use a heat exchanger to reuse energy in the HPT process to reduce the amount of energy input. In this case, the energy input to energy output (Ei/Eo) ranged from 0.34 to 0.55, which was much less than one, suggesting that biogas increment due to heat treatment can reasonably cover the energy consumption of the pre-treatment itself. Thus combining HPT and high-load anaerobic digestion of PM was suitable.
Fibroblast growth factor-23 and the risk of cardiovascular diseases and mortality in the general population: A systematic review and dose-response meta-analysis
Authors: Liu Menglu , Xia Panpan , Tan Ziqi , Song Tiangang , Mei Kaibo , Wang Jingfeng , Ma Jianyong , Jiang Yuan , Zhang Jing , Zhao Yujie , Yu Peng , Liu Xiao 
Published: November 2022

BackgroundIn the past decade, fibroblast growth factor 23 (FGF23) has been recognized as an important biomarker of cardiovascular diseases. This study aimed to assess the relationship between FGF23 and the risk of cardiovascular diseases (CVDs) in general populations.MethodsThe protocol was registered prospectively in PROSPERO (CRD42021281837) and two authors independently searched for relevant studies in the PubMed, EMBASE, and Cochrane Library databases. The random effects model was applied.ResultsIn total, 29 prospective studies involving 135,576 participants were included. In the general population, the category analysis revealed that elevated FGF23 levels were related to increased risks of myocardial infarction (MI) (RR: 1.40, 95%CI: 1.03−1.89), stroke (RR: 1.20, 95%CI: 1.02−1.43), heart failure (HF) (RR: 1.37, 95%CI: 1.23−1.52), CVD events (RR: 1.22, 95%CI: 0.99−1.51), cardiovascular mortality (RR: 1.46, 95%CI: 1.29−1.65), and all-cause mortality (RR: 1.50, 95%CI: 1.29−1.74). In the continuous analysis, per doubling of FGF23 was associated with increased risks of MI (RR: 1.08, 95%CI: 0.94−1.25), stroke (RR: 1.21, 95%CI: 0.99−1.48), HF (RR: 1.24, 95%CI: 1.14−1.35), CVD events (RR: 1.12, 95%CI: 0.99−1.27), cardiovascular mortality (RR: 1.43, 95%CI: 1.09−1.88), all-cause mortality (RR: 1.37, 95%CI: 1.15−1.62). Furthermore, the dose-response analysis demonstrated a potentially non-linear relationship between FGF23 and stroke, HF, and all-cause mortality. In contrast, a potentially linear relationship between FGF23 and cardiovascular mortality was observed (p for non-linearity = 0.73).ConclusionThe present study suggests that increased serum FGF23 levels are positively related to CVD events and mortality in the general population. The clinical application of FGF23 levels to predict CVD risk requires further research.
The hemoglobin glycation index predicts the risk of adverse cardiovascular events in coronary heart disease patients with type 2 diabetes mellitus
Authors: Xu Shuai , Qin Zhen , Yuan Ruixia , Cui Xiaolin , Zhang Li , Bai Jing , Liu Gangqiong , Wang Zeyu , Yu Fengyi , Lv Yan , Zhang Jinying , Tang Junnan 
Published: November 2022

BackgroundPrevious studies have shown that the hemoglobin glycation index (HGI) can be used as a predictor of diabetic complications. However, limited information is currently available to indicate the correlation between HGI and comorbidity of coronary heart disease (CHD) and diabetes. This study aimed to evaluate the potential of HGI to predict major adverse cardiovascular events (MACEs) in CHD patients with type 2 diabetes mellitus (T2DM) undergoing percutaneous coronary intervention (PCI).Materials and methodsA total of 918 CHD patients with T2DM were enrolled in a 3-year retrospective cohort study, from December 2017 to December 2020 at the First Affiliated Hospital of Zhengzhou University. Data including fasting blood glucose (FPG/FBG) and glycated hemoglobin A1c (HbA1c) were collected. HGI was calculated as actual measured HbA1c minus predicted HbA1c. Three groups were further divided based on the levels of HGI, including low, medium, and high levels.ResultKaplan Meier analysis indicated that elevated HGI was strongly associated with the occurence of MACE (log-rank P &lt; 0.001). Multivariate Cox regression analysis revealed that elevated HGI was an independent risk factor for incident MACE in CHD patients with T2DM [adjusted hazard ratio (HR): 1.473; 95% confidence interval (CI): 1.365-1.589, P &lt; 0.001].ConclusionsHemoglobin glycation index is an independent predictor of MACE events in CHD patients with T2DM. High HGI indicates a higher risk of MACE occurrence.
The role of immune profile in predicting outcomes in cancer patients treated with immunotherapy
Authors: Botticelli Andrea , Pomati Giulia , Cirillo Alessio , Scagnoli Simone , Pisegna Simona , Chiavassa Antonella , Rossi Ernesto , Schinzari Giovanni , Tortora Giampaolo , Di Pietro Francesca Romana , Cerbelli Bruna , Di Filippo Alessandra , Amirhassankhani Sasan , Scala Alessandro , Zizzari Ilaria Grazia , Cortesi Enrico , Tomao Silverio , Nuti Marianna , Mezi Silvia , Marchetti Paolo 
Published: November 2022

BackgroundDespite the efficacy of immunotherapy, only a small percentage of patients achieves a long-term benefit in terms of overall survival. The aim of this study was to define an immune profile predicting the response to immune checkpoint inhibitors (ICIs).MethodsPatients with advanced solid tumors, who underwent ICI treatment were enrolled in this prospective study. Blood samples were collected at the baseline. Thirteen soluble immune checkpoints, 3 soluble adhesion molecules, 5 chemokines and 11 cytokines were analyzed. The results were associated with oncological outcomes.ResultsRegardless of tumor type, patients with values of sTIM3, IFNα, IFNγ, IL1β, IL1α, IL12p70, MIP1β, IL13, sCD28, sGITR, sPDL1, IL10 and TNFα below the median had longer overall survival (p&lt;0.05). By using cluster analysis and grouping the patients according to the trend of the molecules, two clusters were found. Cluster A had a significantly higher mean progression free survival (Cluster A=11.9 months vs Cluster B=3.5 months, p&lt;0.01), a higher percentage of disease stability (Cluster A=34.5% vs. Cluster B=0%, p&lt;0.05) and a lower percentage of disease progression (Cluster A=55.2% vs. Cluster B = 94.4%, p=0.04).ConclusionThe combined evaluation of soluble molecules, rather than a single circulating factor, may be more suitable to represent the fitness of the immune system status in each patient and could allow to identify two different prognostic and predictive outcome profiles.
Frailty trajectory over one year among residential aged care (nursing home) residents
Authors: Lim Renly , Kelly Thu-Lan , Andrade Andre Q. , Kalisch Ellett Lisa M. , Bilton Rebecca , Dorj Gereltuya , Pratt Nicole L. , Roughead Elizabeth E. 
Published: November 2022

ObjectivesLarge population-based studies examining frailty trajectory found a linear increase in frailty over time. The pattern in which frailty changes over time for an individual person is less well-described. We examined the frailty trajectory of older adults living in aged-care in Australia.Materials and methodsThis secondary study used data from a randomised controlled trial involving 39 aged-care facilities in Australia. The trial intervention was an on-going pharmacist-led intervention occurring every 8 weeks over 12 months aimed at preventing medicine-induced deterioration and adverse reactions. Frailty was assessed using the Frailty Index. Participants were categorised as non-frail, pre-frail and frail. Individual frailty trajectory over 12 months was visualised using the alluvial plot. Case notes were examined to explore reasons for any rapid transitions in frailty status.ResultsA total of 248 participants was included. At baseline, 40.3% were non-frail and 59.7% were pre-frail. The proportion of participants who were non-frail and pre-frail decreased over time; 15.7% were frail at 6 months and 23.4% were frail at 12 months. Overall, twenty different combinations of frailty transitions were identified over 12 months. Retrospective analysis of case notes suggest that death or transition from non-frail to frail was often preceded by hospitalisation, falls, medication change or clinically significant deterioration in grip strength or cognition.ConclusionThe degree of frailty increased over time, but there were variations in the individual trajectories. Regular monitoring of events that precede changes in frailty status is needed to identify strategies to prevent further deterioration in residents’ conditions.