bluuebunny/crossref_metadata_2025_split huggingface dataset:
Asthma bronchialéban szenvedő gyermekek közösségimédia-használata
Authors: Józsa Tamás , Túry Ferenc 
Published: November 2022

Összefoglaló.
Bevezetés: Az asthma bronchialéban szenvedő fiatalok
egészségmagatartására lényeges hatást gyakorol a virtuális világ (például a
Facebook). Ezt gyakran kötődési hiányállapotaik kompenzálására használják.
Célkitűzés: Az asthmás gyermekek
közösségimédia-használatának vizsgálata egészséges kontrollcsoporttal
összehasonlítva. Módszer: A vizsgálatban 250 fő, 10–18 éves
asthmás, valamint 250 fő, 10–18 éves egészséges gyermek vett részt. Velük a
Facebook Használati Kérdőív, a Ten Item Personality Inventory, a Rosenberg
Önértékelési Skála, a Beck Gyermekdepresszió Kérdőív, valamint a Gyermek
Multidimenzionális Szorongás Skála került felvételre.
Eredmények: Az asthmás gyermekek kevesebb aktív időt
töltenek a Facebookkal, mint az egészségesek (p<0,001), mégis ők érzik azt,
hogy ez a platform inkább az életük része (p<0,001). Az asthmásokat magasabb
depressziószint és szorongás, valamint alacsonyabb önértékelés jellemzi
(p<0,001). Mindkét csoport esetében a lányok használják gyakrabban a
Facebookot. A lányok között a Facebook fokozott használata együtt jár a magasabb
depressziószinttel és szorongással. Következtetés: Az asthmás
gyermekek életében a közösségi média igen jelentős szerepet tölt be. Mivel a
10–18 éves korosztály vulnerábilis ennek addiktív hatásaira, a pszichoedukáció
és a prevenció alapvető volna. Orv Hetil. 2022; 163(15): 593–598.
Summary.
Introduction: The health behavior of patients with asthma
bronchiale can be influenced by the virtual world (e.g.,
Facebook). It is often used to compensate their attachment deficits.
Objective: In this study, the use of social media is
analyzed among asthmatic children compared to a healthy control group.
Method: 250 asthmatic and 250 healthy children were
interviewed from the age of 10 to 18. The Facebook Intensity Scale, the Ten Item
Personality Inventory, the Rosenberg Self-Esteem Scale, the short version of the
Beck Depression Inventory and the Multidimensional Anxiety Scale for Children
were used in the study. Results: Asthmatic children’s social
media time was significantly lower compared to that of healthy children
(p<0.001). However, their feeling of being part of the Facebook community is
the main motivation to use it (p<0.001). Higher scores of anxiety and
depression, and the lower self-esteem compared to the healthy control group can
be detected among asthmatic children (p<0.001). The increased use of Facebook
can be shown in both groups of girls. The increased use of Facebook among girls
is in connection with a higher score of depression and anxiety (p<0.05).
Conclusion: Social media plays a very important role in the
life of asthmatic children. The psychoeducation and prevention is of basic
importance, because the age group of 10–18-year-old children is vulnerable to
the addictive effect of social media. Orv Hetil. 2022; 163(15): 593–598.
Una Propuesta de Corrección en Tasas De Mortalidad por Diabetes Mellitus para Ciudades Colombianas con Problemas de Subregistros, 2005 – 2017
Authors: Sandoval Juan de Jesus , Contreras B. Piedad Urdinola , Sarmiento Paula A. Rivera 
Published: November 2022

El recuento de la mortalidad por enfermedades de baja prevalencia como la Diabetes Mellitus (DM), sufre de problemas serios de subregistro debido a la ausencia de datos, representados en ceros en el sistema de estadísticas vitales, lo que dificulta la necesidad de identificación de los patrones sobre todo de enfermedades que son silenciosas.
Esta investigación propone una corrección a las tasas de mortalidad para poblaciones pequeñas con alta inflación en ceros, como es el caso de la serie anual de Diabetes Mellitus (DM) para ciudades colombianas en edades de 20 a 80 años, entre los años 2005 y 2017. Se propone una modificación al modelo bayesiano jerárquico propuesto por Alexander et al. (2017), reemplazando la distribución original por una Binomial Negativa y utilizando los patrones de defunciones por la misma causa de otros países en la región, en años recientes. Con éste, se corrigieron las tasas de mortalidad por esta causa, edad, sexo y ciudad. Los resultados mostraron una apropiada corrección para las edades que oficialmente reportan ceros, manteniendo la brecha natural entre sexos, y una corrección mayor para las ciudades más pequeñas, frente a las grandes ciudades, cuando se comparó con otros modelos.
Con esta metodología se permitirá ayudar a la vigilancia epidemiológica de las enfermedades de baja prevalencia como la hipertensión, enfermedades coronarias y similares, con altos niveles de subregistro; pero que requieren de mediciones precisas a nivel subnacional para la toma de decisiones de salud pública. Cifras equivocadas solo llevarían a toma de decisiones erróneas, por ello es de vital importancia generar este tipo de correcciones.
Earthquake Delay and Rupture Velocity in Near-Field Dynamic Triggering Dictated by Stress-Controlled Nucleation
Authors: Dong Peng , Chen Rong , Xia Kaiwen , Yao Wei , Peng Zhigang , Elsworth Derek 
Published: November 2022

AbstractDynamic triggering of earthquakes by seismic waves generated by another earthquake is widely observed, while the underlying nucleation mechanisms remain unclear. We report here dynamically triggered earthquakes on laboratory faults with tightly constrained imaging of the triggering process. The arriving stress wave alters the contact state of the laboratory fault and initiates rupture nucleation in two distinct phases. The triggered rupture grows at a fraction of the shear-wave velocity (∼0.4CS) and then transits to a very slow velocity (∼0.1CS) before culminating into runaway shear. This intervening very slow rupture phase is present only for seismic ratios conducive to sub-Rayleigh ruptures and is notably absent for supershear events. Thus, the delay in triggering decreases to a minimum for triggered supershear ruptures, whereas it scales with the stress state for triggered sub-Rayleigh ruptures. These results may help explain key characteristics of delayed near-field dynamic triggering and provide a simple theoretical framework for dynamic triggering at greater distances.
Предварительные результаты многоцентрового российского рандомизированного исследования RUCORT3: лечение больных местнораспространенным раком прямой кишки (МРРПК)
Authors: Полыновский А. В. , Мамедли З. З. , Кузьмичев Д. В. , Анискин А. А. , Алексанцев Д. В. 
Published: November 2022

Цель: оценка эффективности неоадъювантной последовательной индукционной химиотерапии (ХТ), химиолучевой терапии (ХЛТ) и консолидирующей (ХТ) по схеме CapOx у больных МРРПК по показателям 3‑летней безрецидивной выживаемости в сравнении с контрольной группой. В качестве дополнительных целей выделены оценка: частоты выполнения сфинктеросохранящих операций, токсических эффектов лечения, частоты полных морфологических эффектов, частоты рецидивов и метастазов.Методы: С 2019 года по настоящее время в исследование включены пациенты МРРПК со стадией T3 (CRM +) / 4N0–2M0.Результаты: В исследование включено 136 пациентов, полный курс лечения прошли 107 (78,7 %), еще 21 пациент находится в процессе лечения или ожидания операции, остальные исключены по тем или иным причинам (смерть, прогрессирование и др.) Частота токсических осложнений III–IV степени не превышала 4,7 % в группе ХЛТ и 6,8 % в группе ХЛТ + ХТ и была сопоставима. Сфинктеросохраняющие операции в группе ХЛТ + ХТ выполнены у 38 пациентов (67,5 %), по сравнению с 25 (56,7 %) в группе ХЛТ (p = 0,05). Частота послеоперационных осложнений по классификации Clavien‑Dindo оказалась сопоставима в двух группах. Полный морфологический ответ достигнут у 7 (15,9 %) пациентов в группе ХЛТ и у 7 (13,5 %) в группе ХТ + ХЛТ (р = 0,2). Отмечено увеличение частоты возникновения близкого к полному морфологическому ответу (TRG2) в группе ХЛТ + ХТ — 17 (32,7 %) пациентов, против 8 (18,2 %) (p = 0,048). В группе ХЛТ полный курс адъювантной химиотерапии завершили 28,3 % пациентов, в группе ХЛТ + ХТ — 64,9 % (р = 0,05). Медиана наблюдения за пациентами 17 мес. В обеих группах выявлено по 1 рецидиву (1,8 % для группы ХЛТ и 1,7 % для группы ХЛТ + ХТ). Частота отдаленных метастазов в группе ХЛТ составила 14,5 % (8 пациентов), в группе ХЛТ + ХТ 8,7 % (5 пациентов). Достоверности данная разница не имеет, однако различия между группами составили 5,8 %. Показатели 2‑летней безрецидивной выживаемости составили 81 % в группе ХЛТ и 86 % в группе ХЛТ + ХТ соответственно.Заключение: Тотальная неоадъювантая терапия является перспективным направлением в лечении больных МРРПК, позволившая в представленном исследовании продемонстрировать увеличение безрецидивной выживаемости (без статистической достоверности), увеличить частоту достижения близкого к полному морфологического ответа (TRGII) по сравнению с группой ХЛТ и тем самым значимо увеличить частоту выполнения сфинктеросохраняющих операций. Число проведенных курсов химиотерапии статистически значимо выше в группе ХЛТ + ХТ. Для окончательных выводов требуется дальнейшее наблюдение за пациентами из контрольной и исследуемой групп.
Phytosociological survey of weed plants and their pasture control
Authors: Luz do Carmo Silva Gidean , Toniolo Farias Henrique , De Oliveira Neto Joaquim , Vargas Borges Elizene , Wenderson Ribeiro Coutinho Pablo 
Published: November 2022

Weeds damage economically interesting crop development, resulting in potential production loss of such crop. Thus, this study had de objective of surveying weeds’ phytosociology in Brachiaria brizantha (cv. Marandu) pasture and of evaluating the effectiveness of herbicides in mixtures on weeds control. The field studied has been using B. brizantha pasture for more than 10 years, divided in 4 areas with 1 ha each. After the first weeds harvest and identification, a mixture of Aminopyralid (50 g L-1) + Picloram (100 g L-1) + Triclopyr (150 g L-1) 1 L ha-1 + 1.5 L ha-1 of 2,4-D (2.5 L ha-1), Aminopyralid (50 g L-1) + Picloram (100 g L-1) + Triclopyr (150 g L -1) 2.0 L ha-1 + 1.5 L ha-1 of 2,4-D (3.5 L ha-1), Aminopyralid (50 g L-1) + Picloram (100 g L-1) + Triclopyr (100 g L-1) 1 L ha-1 + 1.0 L ha-1 of 2,4-D (2 L ha-1). After the harvests, the samples were identified and the following statistics were calculated — absolute frequency, relative frequency, absolute density, relative density, absolute abundance, relative abundance, and importance value index. The obtained phytosociological survey in pasture planting presented five families — Fabaceae, Malvaceae, Asteraceae, Euphorbiaceae, and Solanaceae —, and using Aminopyralid (50 g L-1) + Picloram (100 g L-1) + Triclopyr (100 g L-1), adding up to a mixture of 1.0 L ha-1, mixed with 1.0 L ha-1 of 2,4-D, was effective in the control of weeds in the pasture area.
Islamic Female Clerics’ Preaching on the Discourse of Woman’s Body, Sexuality and Domestication: A Study through Transitivity and Appraisal Analysis
Authors: Leiliyanti Eva , Munir Hazalia Zahra , Awaliyah Wita 
Published: November 2022

This text-oriented discourse analysis aims to evaluate and compare the language voiced by the two Islamic female clerics’ (Ustazah Aisah Dahlan and Mamah Dedeh) in their preaching as well as their stances towards the Discourse of Muslim Woman’s Body, Sexuality and Domestication posted on their affiliated Youtube accounts during this Covid-19 pandemic. The data (two video transcripts with the duration 09 minutes 04 seconds and 42 minutes and 54 seconds, respectively) were taken based on stratified purposeful sampling. Using transitivity system (ideational metafunction of language) postulated by M.A.K. Halliday(2014) and language evaluation theory (interpersonal metafunction of language) developed by Martin and White (2005), it was found that Aisah Dahlan’s preaching was dominated by attributive relational process and positive judgment in heteroglossic expressions to justify Muslim men’s attitudes and behaviors, whereas negative judgment in force expressions were deployed in discussing the Muslim woman’s body, sexuality, and domestication discourse. On the contrary, Mamah Dedeh’s preaching was dominated by the material process and positive judgement of sanction which indicates that husband and wife share equal responsibility in the household.Keywords: Ustazah, Text-Oriented Discourse Analysis, Muslim Woman’s Body, Islamic views on Sexuality, Domestication of woman, Transitivity analysis, appraisal analysis
COGNITIVE APPROACH IN THE STUDY OF POLITICAL IDEOLOGIES
Authors: Konstantinov Mikhail S. 
Published: November 2022

Aim. Critical analysis and conceptual reception of the cognitive trend in the study of political ideologies.Methodology. In the course of the study, a conceptual-analytical method was used, which made it possible to identify the basic provisions of scientific theory and/or methodology based on the analysis of key scientific texts. The paradigm works of Paul Ricoeur, John Brookshire Thompson and Michael Freeden were analyzed.Results. It is shown that in the understanding of ideologies there has been a significant shift from interpreting this phenomenon as a means of distorting social reality, masking conflicts and contradictions, as well as producing illusions, to a more complex and multi-layered interpretation of ideology as a cognitive matrix of group consciousness as an interpretive code and a symbolic tool for establishing and reproduction of dominance. The concept of ideology within the cognitive approach was conceptualized.Research implications. The systematization of the main conceptual elements of the cognitive approach to the study of political ideologies, carried out in the article, creates the basis for a deeper reception in the domestic social sciences of the methodological tools of this approach and a more adequate understanding of the nature of ideologies.
Risco para lesões por posicionamento cirúrgico decorrentes da posição supina
Authors: CAETANO ÉRICA PATRICIA SOUZA , DE MATTIA ANA LUCIA 
Published: November 2022

Objetivo: relacionar o escore de risco de lesões por posicionamento cirúrgico decorrentes da posição supina com aspectos sociodemográficos, clínicos, cirúrgicos e ocorrência de complicações. Método: estudo observacional longitudinal realizado com 89 pacientes em decúbito dorsal. Aplicadas variáveis ​​sociodemográficas e clínicas e a Escala de Risco para Desenvolvimento de Lesões por Posicionamento Cirúrgico. Adotadas análises descritivas, bivariadas e de regressão logística, considerando-se um nível de significância de α=0,05. Resultados: a idade aumentou em 1,11 vezes (p<0,001) e a obesidade em 13,77 vezes (p=0,01) a chance de aumento do risco de lesões. A proporção de dor (34,1%) e lesão por pressão na região sacrococcígea (91,7%) destacou-se nos pacientes de maior risco (p=0,05). Conclusão: obesos e idosos apresentaram maior risco de lesões. Dor e ocorrência de lesão por pressão na região sacrococcígea foram as complicações predominantes nos pacientes de maior risco.
Large libraries of single-chain trimer peptide-MHCs enable rapid antigen-specific CD8+ T cell discovery and analysis
Authors: Heath James , Chour William , Choi Jongchan , Xie Jingyi , Chaffee Mary , Schmitt Thomas , Finton Kathryn , Delucia Diana , Xu Alexander , Su Yapeng , Chen Daniel , Zhang Rongyu , Yuan dan , Hong Sunga , Ng Alphonsus , Butler Jonah , Edmark Rick , Jones Lesley , Murray Kim , Peng Songming , Li Guideng , Strong Roland , Lee John , Goldman Jason , Greenberg Philip 
Published: November 2022

Abstract
CD8 + cytotoxic T cell responses against viral infection represent a major element of the adaptive immune response. We describe the development of a peptide antigen – major histompatibility complex (pMHC) library representing the full SARS-CoV-2 viral proteome, and comprised of 634 pMHC multimers representing the A*02.01, A*24.02, and B*07.02 HLA alleles, as well as specific antigens associated with the cytomegalovirus (CMV). These libraries were used to capture non-expanded CD8 + T cells from blood samples collected from 64 infected individuals, and then analyzed using single cell RNA-seq. The discovery and characterization of antigen-specific CD8+ T cell clonotypes typically involves the labor-intensive synthesis and construction of peptide-MHC tetramers. We adapted single-chain trimer (SCT) technologies into a high throughput platform for pMHC library generation, showing that hundreds can be rapidly prepared across multiple Class I HLA alleles. We used this platform to explore the impact of peptide and SCT template mutations on protein expression yield, thermal stability, and functionality. SCT libraries were an efficient tool for identifying T cells recognizing commonly reported viral epitopes. We then constructed SCT libraries designed to capture SARS-CoV-2 specific CD8+ T cells from COVID-19 participants and healthy donors. The immunogenicity of these epitopes was validated by functional assays of T cells with cloned TCRs captured using SCT libraries. These technologies should enable the rapid analyses of peptide-based T cell responses across several contexts, including autoimmunity, cancer, or infectious disease.
Effectiveness of laughter augmented Tai Chi exercises on physical and psychosocial aspects of Active Aging in community-dwelling older adults: A Systematic Review
Authors: Bibi Rashida , Yan Zhang , Yue Gao 
Published: November 2022

Abstract
Background
Tai Chi augmented with self-induce laughter (SIL) might be an affordable and effective strategy to improve physical and psychosocial aspect of Active Aging among community-dwelling older adults with or without illness. However, research is required to evaluate the synergic effect of augmented TC for community-dwelling older adults and its outcomes. This research aims to critically assess the claimed advantages of Tai Chi exercise augmented with laughter therapy (TC)&(SILT) can improve physical, and psychosocial aspects of Active Aging in community based older adults.
Methods
researcher conducted an extensive literature search from different databases, and returned 1025 research papers. Searching strategies were followed. The time interval was fixed from 2015 to 2021 to minimize searched papers quantity. Only English language, randomized control trials, and quasi-experimental studies were selected due to novelty of the Tai chi in most of the countries. Only 11 papers met the inclusion criteria of our comprehensive review.
Results
The qualitative assessment resulted that programs containing more fun-based interventions are effective regardless of the type of intervention. The effectiveness is also modulated by other variables such as the participant's education level, gender, current health status, and financial constraints.
Conclusion
This review suggests that the Tai Chi movement blended with laughter could be an effective, feasible, and safe interventional strategy which has positive effects on physical and psychosocial health which of Active Aging status and overall well-being in healthy and non-healthy individuals in old age.
Evaluating a User Interface (Prototype) of a Smart Patient- Oriented Obstetric Ultrasound Report (SPOUR): Second Trimester Report
Authors: Alanazi Eman , Luo Jake , Alanzi Turki M , Wu Min 
Published: November 2022

Abstract
Aim
To evaluate a new obstetric ultrasound report for second trimester scan. In this new designed report, we adopted several ideas related to artificial intelligence applications and UX design principles to mitigate patients’ information needs and increase women understanding of the report.
Method:
This is an interventional study compared a traditionally designed report with our new designed report. We used Amazon Mechanical Turk to recruit childbearing age women who are or were pregnant. We used five evaluation concepts: report understanding, perceived ease of use, perceived usefulness, intention to use, and perceived aesthetics. We also measured the perceived ease of use and perceived usefulness of the new components in the report by asking the interventional group about the new components.
Result:
Understanding the report increased in comparison to the old design P = < 003. We found a significant difference of the Perceived ease of use, perceived usefulness, intention to use, and perceived esthetics in the new designed report comparing to the traditional design. We found that the new components were perceived as easy to use and useful by the majority of respondents.
Conclusion:
The new report increased information understanding among pregnant women. User experience design was one of the aspects we looked at when developing the report. The results showed that understanding the report was higher among the interventional group, demonstrating that reporting through patient portal should take advantage of technology advancements to ensure information is understandable by patients.
Increased RBPs associated with HPV play a role in reducing the survival of patients with head and neck cancer
Authors: Kamli Hossam , Jalil Luay Hatem , Mohammed Nawres Bahaa , Jalil Abduladheem Turki , Mustafa Yasser Fakri , Al-Hamdani Mais Mazin , Samarghandian Saeed , Hashemi Mehrdad 
Published: November 2022

AbstractObjective Head and neck cancer (HNSC) is the sixth most usual type of cancer in the world. The heterogeneity of this type of cancer is more elevated by the rising rate of human papillomavirus (HPV)-related (HPV+) HNSC, which defines an etiological subtype significantly different from the more common tobacco and alcohol associated HPV-negative (HPV-) HNSC. The aim of this study was to identify the RNA-binding proteins (RBPs) with immune role, and study of their relation with HPV status and drug resistance. Methods By using the Cancer Genome Atlas (TCGA) and utilizing clinical data, at the first, differential expressed RBPs analysis was performed and among selected RBPs, the genes which consider as immune genes were identified. Then, downstream analyses to characterize this tumor based on HPV status, including pathway mapping, survival analysis, immune infiltration and drug resistance was conducted. Results 99 differentially expressed genes were detected that were similar in RBPs genes and immune genes (IGs) in HNSC. These genes were enriched in some significant pathway and the association of candidate genes with HPV were applied by Chi-squared test and the level of which were evaluated in HPV + and HPV -. Then, the prognostic value of genes was evaluated in HPV + and the correlation of them with immune infiltration and drug resistance was evaluated. Conclusions Identifying the RBPs with immune role and recognizing the molecular differences between HPV + and HPV − tumors could cause the opportunity to find specific genes and the therapeutic approaches for targeting them.