bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neuroaesthetic, a Bibliometric Analysis
Authors: Saleh Arman Yurisaldi 
Published: April 2022

Abstract
Therapy in the field of neurobehavior is developing rapidly. A new field has emerged that affects the quality of life of patients. The literature review continues to grow. The purpose of this study was to conduct a bibliometric analysis to determine the position of the neuroaesthetic field and the potential for research related to keywords. The method used consists of five steps. This field has the potential to be developed continuously because it has entered into discussions related to behavior and behavior therapy. It is necessary to carry out a bibliometric analysis to broaden a better picture of the neuroaesthetic position. This makes it easier to find topics that are still under-researched.
Prevalence of Weight-Based Stigmatization in a Multi-ethnic Asian Population – A Cross-Sectional Study
Authors: Chue Koy Min , Foo Mang Yik , Chua Cheryl Min En , Toh Bin Chet , Ong Lester Wei Lin , Lim Chin Hong , Tan Jeremy Tian Hui , Chua Marvin Wei Jie , Lee Wai Ching Deanna , Wong Wai Keong , Yeung Baldwin Po Man 
Published: April 2022

Abstract
Aim:
Weight-based stigmatization is prevalent. They have been reported in schools, work and healthcare settings. However, almost all the literature on such weight-based stereotypes were from Western countries. The study aims to evaluate the prevalence of weight-based stigmatization in an Asian population.
Methods:
An anonymized questionnaire-based cross-sectional study was conducted. Respondents were asked about their socioeconomic status, followed by questions on perceived weight-based stigmatization across 4 domains (self, social, healthcare, work and education). A subsequent subgroup analysis was performed to evaluate the impact of different obesity classes on perceived stigmatization across these domains.
Results:
A total of 101 respondents replied. Respondents with higher BMI were middle-aged (p = 0.040), Malays (p = 0.018), low-income (p = 0.041) and had lower educational qualifications (p = 0.038). Total prevalence of perceived weight-based stigmatization was 65.6%. Class III obesity respondents were more stigmatized at work (Prevalence Rate Ratio (PRR) 5.73, 95% Confidence Interval (CI): 1.16–28.47), and resort to increased consumption of unhealthy food or partake in lesser exercise due to stigma (PRR 24.94, 95% CI: 3.61-172.41).
Conclusion:
Obesity stigmatization is equally prevalent in Asian societies. Individuals with higher BMI were more likely to report perceived stigmatization in the workplace, as well as maladaptive dietary and exercise behaviours in response to stigmatization, regardless of socioeconomic status.
Determinants of Missed Nursing Care by Nurses at University Teaching and Referral Hospital (Chuk) of Kigali in Rwanda
Authors: Ntezimana Faustin , Jivraj Nilufa , Dominic Mogere 
Published: April 2022

Abstract
Objective
The aim of this study was to determine the levels, types and the factors that influence Missed Nursing Care activities by nurses at the University Teaching and Referral Hospital of Kigali in Rwanda.
Material and Methods
This study was cross-sectional descriptive correlation design. The researchers used complete coverage method of sampling technique to obtain participants. The researchers used MISSCARE survey questionnaires for data collection with. The data was analysed using SPSS version 26.0. Frequencies, crosstabulation, chi-square and multinomial logistic regression were computed to find the percentage, associations and effects between independent and dependent variables at 95% confidence interval and significance level of 5%.
Results
Two hundred and one (201) nurses took part in the study, 56.7% were female and 46.3% were male. The majority were aged 31–40 years, 54.2% had Diploma, 42.3% had bachelor while 3.5% had master’s degree, and 75.6% were married. The mean experience in nursing and in current unit were 13years and 7years respectively. Missed nursing care was regarded as moderate as perceived by 46.73% of respondents. The study showed that replying to call alarms within 5 minutes, joining interdisplinary whenever held, documentation of necessary information, monitoring intake and output, and patient health education were always being missed by nurses. Institutional unit type (χ2 (6, N = 201) = 63.31, p = 0.001), gender (χ2 (2, N = 201) = 10.35, p = 0.006), orientation (χ2 (2, N = 201) = 9.51, p = 0.009), satisfaction with salary (χ2 (2, N = 201) = 8.25, p = 0.016), level of education (χ2 (2, N = 201) = 10.34, p = 0.006), and ward size were the most statistically significant factors associated with level of missed nursing care activities.
Discussion
Majority, 46.73% of nurses viewed the level of missed nursing care at the hospital as moderate. The top five nursing activities that have always been missed were replying to call alarms within 5 minutes, joining interdisplinary whenever held, documentation of necessary information, monitoring intake and output, and patient health education. The study findings revealed that gender, level of education, and the department in which the nurses work were the most statistically significant factors contributing to missed nursing care at the hospital.
Conclusions
The study findings showed that level of missed nursing care was moderate and it was different across the hospital. The findings also showed that there was top five missing nursing care that are aways missing affected by various factors.
Assessment of health related quality of life and distress in an Asian community-based cancer rehabilitation program
Authors: Tay Matthew Rong Jie , Wong Chin Jung , Aw Hui Zhen 
Published: April 2022

Abstract
Background: Cancer survivors have reduced health related quality of life (HRQOL) and high levels of distress during and after active treatment, due to physical, psychological and social problems. Understanding the prevalence and associations of HRQOL and distress in a patient population in the community is important to design rehabilitation programs. Methods: This was a cross-sectional observational study conducted at a community-based cancer rehabilitation center, with the aim of investigating the prevalence and associations of HRQOL and distress in cancer patients. Results: There were 304 patients who were recruited. We found low levels of HRQOL and high levels of distress in patients, with a mean FACT-G7 total score of 11.68, and a mean distress thermometer score of 3.51. In the multivariate regression model, significant factors for low QROL were metastatic disease (OR=2.98; 95% CI = 1.15-7.72; p=0.025) and Malay ethnicity (OR=0.157; 95% CI = 0.056-9.44; p<0.001). Regression analyses also found that significant distress were associated with family health issues (OR=4.27; 95% CI=1.41-10.71; p=0.003), depression (OR=8.34; 95% CI=2.51-28.04; p=0.001), worry (OR=3.08; 95% CI=1.41-6.75; p=0.005), breathing (OR=4.59; 95% CI=1.52-13.86; p=0.007), getting around (OR=4.03; 95% CI=1.36-11.95; p=0.012) and indigestion (OR=3.31; 95% CI=1.06-10.32; p=0.039).Conclusions: A high prevalence of impaired HRQOL and distress was reported in cancer survivors even in a community rehabilitation setting. The physical and psychosocial well-being of cancer survivors should be monitored and managed as part of community-based cancer rehabilitation.
Increase in veterinary prescriptions of azithromycin during the COVID-19 pandemic in Brazil
Authors: Fiol Fernando Del , Bergamaschi Cristiane Cassia , Andrade Isaltino Pereira , Silva Marcus Tolentino , Barberato-Filho Silvio 
Published: April 2022

Abstract
Introduction:
With the advent of the pandemic in 2020 and the lack of perspectives for the treatment of COVID-19, numerous therapeutic proposals have emerged for the disease, including hydroxychloroquine and azithromycin. Therefore, some studies have shown that in many countries, the demand for azithromycin has increased during the pandemic. In Brazil, antibiotics can only be purchased with a medical, dental, or veterinary prescription. This study aimed to determine whether the number of prescriptions made by veterinarians (which could be used by humans) has increased during the pandemic. Data on the purchase of antibiotics made under veterinary prescriptions in Brazilian pharmacies between 2014 and 2021 were collected. To assess the changes in monthly trends in the use of the selected antibiotics, we applied the Joinpoint regression.
Results
The most prescribed antibiotic in all years was cephalexin (35%), followed by amoxicillin (24%). During the pandemic, the sales of azithromycin substantially increased. Regression analysis showed that since 2014, azithromycin prescriptions grew by an average of 0.67% per month. At the beginning of the pandemic, the monthly growth rate became 12.64%. When comparing azithromycin sales during the pandemic with the historical average (2014–2019), the increase was 41%.
Conclusions
During the pandemic, there was no animal health situation in Brazil that required the use of this antibiotic. Veterinary prescriptions may have been an instrument for human access to azithromycin for the treatment of COVID-19. Stricter enforcement policies are needed to address this problem to avoid antimicrobial resistance.
Novel antimicrobial peptides with bactericidal effect against Methicillin-resistant Staphylococcus aureus &amp; biofilm forming Methicillin-resistant Staphylococcus aureus
Authors: Lafi Feras F. , Salama Ali , almaaytah ammar 
Published: April 2022

Abstract
With the recent rise of multidrug-resistant bacteria (MDRB) in most communities, it has become one of the most important concerns confronting health professionals globally. Today, Methicillin-resistant Staphylococcus aureus (MRSA) is a major pathogen responsible for a great deal of hospital-acquired (nosocomial) and community-acquired infections. MRSA is difficult to treat with limited options for treatment such as vancomycin, linezolid, or clindamycin. Thus, an innovative methodology is required to compact infections with resistant organisms. In this study we synthesis a novel ultra-short antimicrobial peptide consists of three unit of tryptophan and three unit of lysine. We examined the effect of this peptide against MRSA and biofilm forming MRSA. Promising result showed that the peptide was effective in killing against both MRSA and biofilm forming MRSA with low toxicity to human red blood cells. Moreover, our novel peptide also show excellent synergistic effect when combined with vancomycin against MRSA. Furthermore, combination of our peptide with levofloxacin and clarithromycin revealed synergistic effect with biofilm forming MRSA. In conclusion, the result of this study presented a novel USAMPs which potentially can be utilized as a new generation of antibiotics to compact resistant bacteria globally.
Values of nitric oxide and superoxide dismutase in cerebrospinal fluid of patients with sporadic amyotrophic lateral sclerosis
Authors: Djordjevic Gordana , Ljubisavljevic Srdjan , Stojanov Aleksandar 
Published: April 2022

Abstract
Background: Neurons are highly energy-dependent and highly specialized cells, showing great sensitivity to oxidative stress (OS). This study aimed to contribute to the further elucidation of the role of OS in the pathogenesis of amyotrophic lateral sclerosis (ALS). Matherial and methods: We assessed nitric oxide () and superoxide dismutase (SOD) levels in cerebrospinal fluid (CSF) of 24 sporadic ALS (sALS) patients (13 of them presented with spinal form while 11 patients had bulbar form) and 20 controls (CG).Results: The obtained SOD levels in sALS patients were lower than those in CG (p<0.001), while NO showed higher levels compared to CG (p < 0.001). Observed separately, there were no significant differences in the levels of NO and SOD in CSF between patients about their clinical presentations (p > 0.05). There were significant negative correlations between SOD and NO levels in all sALS patients (r = 0.31, p=0.025). Significant correlation between SOD and functional rating scale as well as disease progression index were recorded in patients with sALS (r=0,618 r= 0.425 p < 0.01), while NO levels were significantly associated with disease progression only (r=0.348 p < 0.01). Conclusion: The data presented here clearly support the role of impaired oxidant/antioxidant balance in the pathogenesis of ALS. The CSF SOD and NO level might serve as a useful biomarker for functional disorder and progression of the disease, but these facts need to be reevaluated in future research which should be performed on a large cohort of ALS patients
Initial studies of the response of rubber tree seedlings treated with saprobic fungi from the semiarid region of Northeast Brazil to anthracnose
Authors: Lopes Marcela Pagoti Bergamini , Gomes Marcela Eloi , Anjos Louyne Varini Santos dos , Celin Gustavo Silva , Henrique Rodney Lucio Pinheiro , Magalhães Izabela Ponso , Pascholate Sergio F. , Furtado Edson Luiz , Firmino Ana Carolina 
Published: April 2022

Abstract
Anthracnose, caused by fungi of the genus Colletotrichum, is present in the main areas where rubber trees (Hevea brasiliensis) are planted. Thus, considering that biological agents can be an alternative for disease control, the present study aimed to carry out initial studies to investigate the response of rubber tree seedlings inoculated with Colletotrichum and treated with saprobes fungi from the semiarid region of Northeast Brazil (Curvularia eragrostidis, Memnoniella levispora, Myrothecium roridum and Phialomyces macrosporus). Seedlings of the rubber tree clone RRIM600 were sprayed with biocontrol agents as preventive and curative treatments seven days before and after C. tamarilloi inoculation, respectively. Assessments included plant response to disease expression based on percentage of symptomatic area on treated leaves, percentage of graft death, and percentage of apical death in seedlings 30 days after inoculation with C. tamarilloi. In addition, the enzymes peroxidase and phenylalanine ammonia lyase (PAL) had their activity quantified by their association with plant resistance to pathogens. The fungus C. eragrostidis had the best result in controlling anthracnose when applied as a preventive treatment, showing 10% less disease than the untreated plant. The same was observed for the fungus P. macrosporus when used in the curative form. These fungi also reduced the graft death. In these cases, PAL activity was higher and may be linked to the induction of resistance against the pathogen. The peroxidase activity was not expressive for treatments with saprobic fungi in the periods studied. Therefore, among the tested fungi, C. eragrostidis and P. macrosporus are promising for the control of anthracnose, deserving further studies.
Exclusion of plant input affects the temperature sensitivity of soil carbon decomposition
Authors: Zhang Xiuwei , Zhu Biao , Yu Fei-Hai , Wang Peng , Cheng Weixin 
Published: April 2022

Abstract
Plant residue input plays a vital role in cropland carbon (C) balance, which can be greatly affected by climate change. Our knowledge of the effect of plant residue on soil respiration is crucial for evaluating C exchange between the atmosphere and terrestrial ecosystems, but large uncertainties remain in the effect of plant input on the temperature sensitivity (Q10) of soil organic carbon (SOC) decomposition in cropland ecosystems. Here, we tested the effect of long-term exclusion of plant input on the Q10 of SOC decomposition by incubating soils collected from two bare fallow (including a Mollisol and an Alfisol with different climate and land-use history) and adjacent old field plots at 10°C and 20°C for 815 days. The ‘equal-time’, ‘equal-C’, ‘one-pool model’ and ‘two-pool model’ methods were used to evaluate the Q10 of SOC decomposition. Results indicated that in the early stage of incubation, exclusion of plant input increased the Q10 (Alfisol) or had minor effect on the Q10 (Mollisol), which may be related to the interactions between substrate quality decrease (increase of chemical stability) and clay mineral suppression on microbial decomposition. However, in the later stage of incubation, plant residue removal decreased the Q10 values in both soils possibly due to the limitation of substrate availability on microbial decomposition. Overal, the role of plant input in the temperature sensitivity of SOC decomposition should be considered when predicting SOC stocks in a future warmer world.
Structural and bioactivity evaluation of molybdenum-doped phosphate glasses: drug delivery application
Authors: Fayad Amira , El-Bassyouni Gehan , Abdel-Baki Manal , Ahmed Manar 
Published: April 2022

Abstract
Boro-phosphate glasses of stoichiometric chemical formula of (50-x)P2O5-20B2O3- 20CaO-10Na2O (x = 5–15 mol. % MoO3), have been prepared using melt-quenching technique. Structural and bioactivity properties of these glasses were considered. The bioactivity was evaluated upon 14 days of soaking in simulated body fluid (SBF) using: XRD, FT-IR and SEM. Through these techniques the creation of the calcium phosphate biolayer as one of the transitional yields of biomineralization is affirmed. Moreover, glass samples were examined as a drug delivery for ciprofloxacin (CIP) antibiotic. It was noticed that the higher the MoO3 content the faster was the drug release rate. Textural analysis elucidated that by increasing the content of MoO3, the surface area was increased. Mathematical models help to design a controlled drug release system. CIP in vitro release mechanism was determined by fitting different dissolution data into two different release models Zero Order and Higuchi model.
Experimental investigation into weld cladding of Ni-WC MMC overlays by CMT process
Authors: Karimi Mohammad Reza , Wang Sheng-Hui , Jelovica Jasmin 
Published: April 2022

Abstract
In the search for versatile and effective weld cladding processes to deposit ultra-wear-resistant Ni-WC MMC (Ni-based tungsten carbide metal matrix composite) overlays for mining applications, there is an increasing interest in exploring advanced low-heat-input cold metal transfer (CMT) method. Depositions of single weld bead tracks of Ni-WC MMCs on steel plates were performed by employing CMT process; Taguchi design of experiments was used to plan the experimental investigation. All weld tracks exhibit continuous and uniform bead profile and sound metallurgical bonding to the substrate. Retained WCs are present in the overlay tracks relatively uniformly. Formation of primary WC and secondary carbides is observed depending on the level of dilution. In contrast to traditional gas metal arc welding (GMAW) processes, volume fraction of retained WC (fWC) is not directly correlated with heat input for CMT process, and can reach a high level together with improved weld bead appearance at high deposition rate. fWC is negatively correlated with dilution rate. Deposition rate has a positive correlation with average instantaneous power, which is, in turn, positively correlated with wire feed speed. Addition of oxygen into shielding gas mixtures promotes carbide transfer from cored feed wire to the weld track and increases fWC. Analysis of Signal-to-Noise ratios shows that it is difficult to find a single set of optimized process control parameters, and trade-offs are needed in the engineering practice. The present investigation demonstrates that CMT process has a clear advantage for depositing Ni-WC MMC overlays over traditional GMAW technologies and that Taguchi method is a powerful tool in process improvement for weld cladding of Ni-WC MMC overlays.
Antimicrobial Evaluation of Sequentially extracted Leaf of Vernonia auriculifera Hiern (Rejicho)
Authors: Etiso Teshale , Suleman Sultan , Mohamed Tesfaye 
Published: April 2022

Abstract
Background: Though there are reports about V. auriculifera antimicrobial activity, there is not enough information about its activity on some of the bacterial and fungal species. Besides, there was no quantitative evaluation done for phytochemicals previously. Therefore, the main purpose of this research work is to evaluate the antimicrobial activity and quantitative evaluation of the phenol and flavonoid contents V. auriculifera. Objectives: The objective of this study was to conduct the antimicrobial and quantitative evaluation of a sequentially extracted leaf of Vernonia auriculifera Hiern. Methods: The leave samples of Vernonia auriculifera were collected from Hawassa Zuria woreda, Sidama region of Ethiopia. The collected leaves of the plant were cleaned with tap water and air-dried. Then, it was coarsely powdered by mortar and pestle. The extractive value of the leaf part of the plant was determined in different solvents. The grounded leaf product was subsequently extracted by hexane, chloroform, and methanol in maceration conical flasks. The phytochemical screening was done for each extract. Then the total phenol and total flavonoid content in each extract were determined. Standard strains of bacterial and fungal species were used to assess the antibacterial, antifungal susceptibility test and to determine the minimum inhibitory concentration of crude extract. Result: Extraction yield for hexane, chloroform, and methanol was 0.6±0.05%, 1.7±0.02%, and 3.3±0.01% respectively. Phytochemical screening has shown the presence of multiple constituents. The TLC analysis depicted the presence of a different number of constituents in three extracts. The total phenolic content of methanol extract was 72.998 ± 0.002 mg GAE /g. The total flavonoid content of hexane and chloroform extracts were 2.59 ± 0.004 mg QE/g and 9.6 ± 0.02 mg QE/g respectively. The antimicrobial activity test showed the chloroform extract was the most active against all test microorganisms. Conclusion: This study has shown the activity of V. auriculifera against selected microorganisms of study. This plant could be used as a crude drug to treat infection caused by these pathogenic microorganisms. It had enough phenol and flavonoid amount that made V. auriculifera exhibit its biological activity.
Comparison of Corneal Flap Thickness Predictability and Architecture Between Femtosecond Laser and Sub-bowman Keratomileusis Microkeratome in Laser in Situ Keratomileusis.
Authors: Rattan Suzan Amana , Rashid Riyam Faihan , Mutashar Mahir Kadhim , Nasser Yaser A.R. , Anwar Didar Sddeq 
Published: April 2022

Abstract
Purpose of the Study:The purpose of the study is to assess and compare the corneal flap thickness predictability and uniformity between Visumax femtosecond laser and Moria sub-Bowman keratomileusis microkeratome in laser in situ keratomileusis procedure to correct myopic and myopic astigmatism refractive errors. Methods:One hundred eyes from 100 patients, were enrolled in this study. Only one eye (right eye) of each patient was chosen for this study. They were divided into two groups of equal size (50 each). Target flap thickness was 90 μm. Flap thickness was measured by anterior segment optical coherence tomography in 7 specified positions at 3 months postoperative.Results:For femtosecond laser group, the average central flap thickness (CFT) was 91.35µm ±4.97. There was no statistically significant difference between the target flap thickness and the resultant flap thickness (p=0.12). When the central, nasal and temporal thicknesses in the same flap were compared, there was no statistically significant difference among these measurements (p=0.9).For the microkeratome group, CFT was 102.18µm±5.63. There was statistically significant difference between the target flap thickness and the resultant flap thickness (p=0.001).The central, nasal and temporal thicknesses were compared and there was a statistically significant difference.(p=0.000).Conclusions:Our study is among few studies in the literature comparing femtosecond laser flap to SBK microkeratome flap. Femtosecond laser creates more predicable flap thickness and more uniform flap architecture. It should be the first choice for the patients when the availability and cost is not a problem. TRIAL REGISTRATION: Trial registration number: NCT04684888. Trial Registration date: December 2020. Registered at www.clinicaltrials.gov.