bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bleeding disorders in implant dentistry: a narrative review and a treatment guide
Authors: Römer Paul , Heimes Diana , Pabst Andreas , Becker Philipp , Thiem Daniel G. E. , Kämmerer Peer W. 
Published: April 2022

Abstract
Purpose
Considering a high prevalence of congenital and especially acquired bleeding disorders, their heterogeneity and the multitude of possible treatments strategies, a review of the scientific data on this topic is needed to implement a treatment guide for healthcare professionals.

Methods
A selective literature review was performed via PubMed for articles describing oral surgery / dental implant procedures in patients with congenital and acquired bleeding disorders. Out of the existing literature, potential treatment algorithms were extrapolated.

Results
In order to assess the susceptibility to bleeding, risk stratification can be used for both congenital and acquired coagulation disorders. This risk stratification, together with an appropriate therapeutic pathway, allows for an adequate and individualized therapy for each patient. A central point is the close interdisciplinary cooperation with specialists. In addition to the discontinuation or replacement of existing treatment modalities, local hemostyptic measures are of primary importance. If local measures are not sufficient, systemically administered substances such as desmopressin and blood products have to be used.

Conclusions
Despite the limited evidence, a treatment guide could be developed by means of this narrative review to improve safety for patients and practitioners. Prospective randomized controlled trials are needed to allow the implementation of official evidence-based guidelines.
Prolonged Use of Proton Pump Inhibitors and Risk of Type 2 Diabetes: Results From a Large Population-Based Nested Case-Control Study
Authors: Ciardullo Stefano , Rea Federico , Savaré Laura , Morabito Gabriella , Perseghin Gianluca , Corrao Giovanni 
Published: April 2022

Abstract

Context
It is still debated whether prolonged use of proton pump inhibitors (PPIs) might affect metabolic health.

Objective
To investigate the relationship between prolonged use of PPIs and the risk of developing diabetes.

Methods
We performed a case-control study nested into a cohort of 777 420 patients newly treated with PPIs between 2010 and 2015 in Lombardy, Italy. A total of 50 535 people diagnosed with diabetes until 2020 were matched with an equal number of controls that were randomly selected from the cohort members according to age, sex, and clinical status. Exposure to treatment with PPIs was assessed in case-control pairs based on time of therapy. A conditional logistic regression model was fitted to estimate the odds ratios and 95% CIs for the exposure-outcome association, after adjusting for several covariates. Sensitivity analyses were performed to evaluate the robustness of our findings.

Results
Compared with patients who used PPIs for &lt; 8 weeks, higher odds of diabetes of 19% (95% CI, 15-24), 43% (38-49), and 56% (49-64) were observed among those who used PPIs for between 8 weeks and 6 months, 6 months and 2 years, and &gt; 2 years, respectively. The results were consistent when analyses were stratified according to age, sex, and clinical profile, with higher odds ratios being found in younger patients and those with worse clinical complexity. Sensitivity analyses revealed that the association was consistent and robust.

Conclusions
Regular and prolonged use of PPIs is associated with a higher risk of diabetes. Physicians should therefore avoid unnecessary prescription of this class of drugs, particularly for long-term use.
Associations of Moderate Low-Carbohydrate Diets With Mortality Among Patients With Type 2 Diabetes: A Prospective Cohort Study
Authors: Wan Zhenzhen , Shan Zhilei , Geng Tingting , Lu Qi , Li Lin , Yin Jiawei , Liu Liegang , Pan An , Liu Gang 
Published: April 2022

Abstract

Context
A statement of context for the abstract was added in Objective as follows: Lower-carbohydrate-diet (LCD) has been reported to have beneficial effects on cardiovascular risk factor profile in general population. However, whether adherence to an LCD could benefit long-term survival among individuals with diabetes is unclear.

Objective
This work aimed to investigate the associations of different types of lower-carbohydrate diets with mortality among individuals with type 2 diabetes (T2D).

Methods
This prospective study included 5677 patients with T2D. The overall, unhealthy, and healthy lower-carbohydrate-diet (LCD) scores were calculated based on the percentage of energy from total and subtypes of carbohydrate, protein, and fat. Deaths were determined via linkage to the National Death Index records until December 31, 2015. Cox proportional hazards models were used to estimate the hazard ratios (HRs) and 95% CIs of mortality.

Results
During a median of 6.3 years of follow-up (39 401 person-years), 1432 deaths were documented. After multivariable adjustment including lifestyle factors, diabetes duration, and glycated hemoglobin A1c, patients in the third quartile of overall LCD score had the lowest risk of mortality (HR: 0.65; 95% CI, 0.50-0.85), compared with the first quartile. The multivariable-adjusted HRs (95% CIs) of mortality across quartiles of healthy lower-carbohydrate-diet score were 1.00 (reference), 0.78 (0.64-0.96), 0.73 (0.58-0.91), and 0.74 (0.58-0.95) (Ptrend = .01). Isocalorically replacing 2% of energy from carbohydrates with plant-based protein or polyunsaturated fatty acids was associated with 23% to approximately 37% lower total mortality. Similar results were observed when analyses were stratified by age, sex, race/ethnicity, smoking status, body mass index, physical activity, and diabetes duration.

Conclusion
Healthy LCD score was significantly associated with a lower risk of mortality in adults with T2D. Adherence to a well-balanced moderate lower-carbohydrate diet that emphasizes healthy carbohydrates, plant-based protein, and polyunsaturated fat may prevent premature death among patients with T2D.
In Patients Undergoing CRS/HIPEC for Colorectal Adenocarcinoma with Peritoneal Metastases, Presence of Ascites on Computed Tomography Imaging is not a Prognostic Marker for Survival
Authors: Said Ibrahim , Ubink Inge , Ewalds Roos S. G. , Arkesteijn Johanna G. T. , Verheul Henk M. W. , de Wilt Johannes H. W. , Dekker Helena M. , Bremers Andreas J. A. , de Reuver Philip R. 
Published: April 2022

Abstract
Background
Cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is a potentially curative treatment for patients with colorectal peritoneal metastases (CRPM). Patient selection is key to optimizing outcomes after CRS/HIPEC. The aim of this study was to determine the prognostic value of ascites diagnosed on preoperative imaging.

Methods
A prospective database of patients eligible for CRS/HIPEC between 2010 and 2020 was retrospectively analyzed. The presence of ascites, postoperative complications, overall survival (OS), disease-free survival (DFS), and completeness of cytoreduction were assessed. Univariable and multivariable logistic regression was performed to identify independent predictors for outcome.

Results
Of the 235 included patients, 177 (75%) underwent CRS/HIPEC while 58 (25%) were not eligible for CRS/HIPEC. In 42 of the 177 patients (24%) who underwent CRS/HIPEC, ascites was present on preoperative computed tomography (CT) imaging. Peritoneal Cancer Index (PCI) score was significantly higher in patients with preoperative ascites compared with patients without (11 [range 2–30] vs. 9 [range 0–28], respectively; p = 0.011) and complete cytoreduction was more often achieved in patients without ascites (96.3% vs. 85.7%; p = 0.007). There was no significant difference in median DFS and OS after CRS/HIPEC between patients with and without ascites {10 months (95% confidence interval [CI] 7.1–12.9) vs. 9 months (95% CI 7.2–10.8), and 25 months (95% 9.4–40.6) vs. 27 months (95% CI 22.4–31.6), respectively}.

Conclusions
Ascites on preoperative imaging was not associated with worse survival in CRS/HIPEC patients with CRPM. Therefore, excluding patients from CRS/HIPEC based merely on the presence of ascites is not advisable.
O grito das multidões: uma poética das vozes em luta para vencer o silêncio
Authors: Berenice da Cruz Maria de Fátima 
Published: April 2022

RESUMO: Neste momento pandêmico em que o silêncio se torna fator preponderante para repensarmos a vida e a morte, eis que surge uma obra poética de forte impacto reflexivo sobre a nossa história, memória e existência. Vozes em Luta: poemas para vencer a solidão (2020) convida o leitor a refletir sobre a condição de ser humano a partir de sua imersão pessoal. Desse modo, este artigo analisa a poética de Lícia Soares de Souza, tomando como fundamento para a análise um diálogo com dois temas presentes nos estudos de Jean-Paul Sartre, a náusea e a angústia. O livro é composto de 51 poemas; contudo, para uma eficaz consecução metodológica, foi feito um recorte de amostragem para uma melhor imersão temática.
PALAVRAS-CHAVE: Angústia, Náusea, Solidão
Changes of landscape structure and soil production function since the 18th century in north-west saxony
Authors: Baude Mike , Meyer Burghard C. 
Published: April 2022

The objectives of this paper are (1) to reconstruct time series of the historical and current landscape structures based on historical documents and serial cadastral maps, (2) to analyse the changes of agricultural production function by the application of historical soil assessments and (3) to analyse the connections between landscape structure and production function in reference to the social and economic driving forces.
The case study area is today an intensively-used agricultural landscape located nearby Taucha-Eilenburg (NW-Saxony), Germany. Arable landscapes in Germany are changing with increasing dynamics: valuable structures and landscape functions of the traditional and multifunctional landscape were lost. New landscape structures replaced the traditional ones slowly or sometimes also in short time steps. Therefore, this paper focuses on the changes of landscape structures and that of the soil production function induced by land use since the 18th century. The changes are analysed on the basis of historical and serial cadastral maps and documents by covering four time steps from 1750 to 2005. The historical maps were scanned, geo-referenced and digitalised in GIS. Thus, quantitative analysis of landscape structure changes on parcel level is enabled. The production function is explicitly reconstructed on the basis of the Prussian Taxation of the real estate of 1864 (Preußische Grundsteuerbonitierung) and The German Soil Taxation (Reichsbodenschätzung) of 1937.
Changes observed on the serial cadastral maps were linked with the social and economical driving forces and the soil production function. Moreover, there is a high demand for the development of methodologies to analyse and to assess time series of landscape structures, land use and landscape functions in the historical context of landscape development.
The historical evolution of military logistics and the analysis of Turkish Independence War in the scope of the Great Offensive (1922) stage
Authors: Hanağası Uğur Baran , Ercan Arda 
Published: April 2022

The concept of logistics has been togetherly uttered with the art of military. Logistics is a military knowledge which has emerged because of the necessity of supplying subsistence weapons, health services, accommodation and transportation conditions forth earmy and it has been a vital factor for each wars of the man kind history. This term, which has been used with the armies that changed the path of the history, is used not only with the military but also with trade. Throughout the ages, supporting the armies has become more complicated as the size of them has been expanded. Naturally, the origin of word logistics, logistikos that means ‘‘calculating wisely’’ pinpoints the importance of this knowledge for the effective advances of the armies in wars. From the ancient times to the present day, the armies that have been specialized in logistics reached out the victories in an easier war. War strategy thinkers like SunTzu, Antoine-Henri Jominiand Carl von Clause witz have emphasized the importance of supporting the armies and explained logistics in their works. In our work, after explaining the importance and historical evolution of military logistics and its literature by giving examples from warfare history, the Great Offensive (1922) that was an one of the most important chapter sandcase of existence of the Turkish History will be evaluated by the analysis of military logistics of the event.
​Extended English summary is in the end of Full Text PDF (TURKISH) file.

Özet

Lojistik kavramı antik çağlardan itibaren askerlik sanatı beraber ile anılmıştır. Savaş sırasında ve askeri harekatlarda ordunun ihtiyacı olan yiyecek içeceğin, silah, sağlık hizmetleri, ulaşım koşulları ve barınmanın temin edilmesi gereksiniminden doğan ve bir askerlik bilgisi olan lojistik insanlık tarihinin her savaşında etkin bir faktör olmuştur. Tarihin yönünü değiştiren savaşlar ve bunların parçası olan orduları zafere götüren en önemli olgulardan biri olan bu kavram, günümüzde askerlik kadar ticaret ile de beraber anılmaktadır. Çağlar boyunca hücum eden kuvvetlerin en iyi şekilde desteklenmesi özellikle büyüyen ordular ile daha da karmaşık bir hal almıştır. Doğal olarak lojistik kelimesinin Yunanca kökeni olan logistikos’un da taşıdığı mana olan ‘‘mantıklı hesaplama’’ orduların savaşlarda sağlıklı ilerlemelerinde önem arz etmeye başlamış, Antik çağlardan günümüze kadar lojistik konusunda uzmanlaşan ordular zafere daha kolay ulaşabilmişlerdir. Ünlü askeri stratejistler Sun Tzu, Antoine-Henri Jomini ve Carl von Clausewitz eserlerinde ordunun lojistik anlamda desteklenmesine atıfta bulunarak, bu kavramı eserlerinde açıklamışladır. Çalışmamızda lojistiğin askerlik sanatında ki önemini ve tarihsel evrimini izah edip, tarihi savaşlarda lojistiğin kullanılma biçimlerini hatırlattıktan sonra, Türk Tarihi’nin en önemli fasıllarından birini oluşturan ve bir ulusun varoluşunu simgeleyen Büyük Taarruz’un lojistik açısından değerlendirilmesine yer verilecektir.
Harnack inequality for parabolic equations with coefficients depending on time
Authors: Paronetto Fabio 
Published: April 2022

Abstract
We define a homogeneous De Giorgi class
of order

p
=
2

{p=2}

that contains the solutions of evolution equations of the types

ξ
⁢

(
x
,
t
)

⁢

u
t

+

A
⁢
u

=
0

{\xi(x,t)u_{t}+Au=0}

and

(

ξ
⁢

(
x
,
t
)

⁢
u

)

t

+

A
⁢
u

=
0

{(\xi(x,t)u)_{t}+Au=0}

,
where

ξ
>
0

{\xi>0}

almost everywhere and A is a suitable elliptic operator.
For functions belonging to this class, we prove a Harnack inequality.
As a byproduct, one can obtain Hölder continuity for solutions of a subclass of the first equation.
Arithmetic convolution sums derived from eta quotients related to divisors of 6
Authors: Ikikardes Nazli Yildiz , Hwang Jihyun , Kim Daeyeoul 
Published: April 2022

Abstract
The aim of this paper is to find arithmetic convolution sums of some restricted divisor functions. When divisors of a certain natural number satisfy a suitable condition for modulo 12, those restricted divisor functions are expressed by the coefficients of certain eta quotients. The coefficients of eta quotients are expressed by the sine function and cosine function, and this fact is used to derive formulas for the convolution sums of restricted divisor functions and of the number of divisors. In the sine function used to find the coefficients of eta quotients, the result is obtained by utilizing a feature with symmetry between the divisor and the corresponding divisor. Let

N
,
r

N,r

be positive integers and

d

d

be a positive divisor of

N

N

. Let

e

r

(

N
;

12

)

{e}_{r}\left(N;\hspace{0.33em}12)

denote the difference between the number of

2
N

d

−
d

\frac{2N}{d}-d

congruent to

r

r

modulo 12 and the number of those congruent to

−
r

-r

modulo 12. The main results of this article are to find the arithmetic convolution identities for

∑

a

1

+
⋯
+

a

j

=
N

(

∏

i
=
1

j

e

ˆ

(

a

i

)

)

{\sum }_{{a}_{1}+\cdots +{a}_{j}=N}({\prod }_{i=1}^{j}\hat{e}\left({a}_{i}))

with

e

ˆ

(

a

i

)

=

e

1

(

a

i

;

12

)

+
2

e

3

(

a

i

;

12

)

+

e

5

(

a

i

;

12

)

\hat{e}\left({a}_{i})={e}_{1}\left({a}_{i};\hspace{0.33em}12)+2{e}_{3}\left({a}_{i};\hspace{0.33em}12)+{e}_{5}\left({a}_{i};\hspace{0.33em}12)

and

j
=
1
,
2
,
3
,
4

j=1,2,3,4

. All results are obtained using elementary number theory and modular form theory.
Aproximación al territorio urbano de Madīnat Lawša (Loja, Granada). La ciudad nazarí desde nuevas perspectivas.
Authors: Sánchez Martínez Juan Alonso 
Published: April 2022

Se ofrece un renovado acercamiento a la fisonomía urbana de madīnat Lawša (Loja, Granada) como “ciudad media” del reino nazarí. Partiendo de fuentes archivísticas, arqueológicas, catastrales y planimétricas, en el texto se redundan, se matizan o se presentan conclusiones inéditas sobre lo que fuera el sistema defensivo de la ciudad medieval y sus sistemas de equipamientos comunitarios.
Sürdürülebilirlik Uygulamalarının Sosyal Medya İletişiminde Kullanımı: Bankacılık Sektörü Özelinde Bir Değerlendirme
Authors: KOTAN TÜRKDEN Duygu , KUŞAY Yeliz 
Published: April 2022

Kurumların sosyal, ekonomik ve çevresel yönetim anlayışları var olan değerleri geleceğe taşıma ihtiyacını gerektirmektedir. Bu gereksinimi sürdürülebilir kılacak en önemli etkenlerden biri de paydaş ilişkileri ya da iletişimsel anlamda hedef kitle iletişimidir. Son yıllarda ise kurumların sosyal sorumluluk anlayışı gereği yürüttükleri iletişim stratejileri, değişen toplumsal yapı, kaynakların sınırlılığı, çevresel problemler, toplumsal eşitsizlik gibi konuların daha sık tartışılmasıyla birlikte birçok kurumu yalnızca bir alan seçip bu alanda toplumu bilinçlendirme, herhangi bir toplumsal konuya dikkate çekme, farkındalık yaratma odağında tasarlanan kurumsal sosyal sorumluluk anlayışının ötesinde kurumların kendi iş süreçlerinden başlayarak yeniden yapılanmasını gerekli kılmaktadır. Bu kapsamda sürdürülebilirlik anlayışı da birbirine entegre bir yapıyı iletişim sürecine aktararak bütünselliği sağlamakta ve kurumları geleceğe taşımaya çalışmaktadır.Bu çalışmada Türkiye’deki bankacılık sektörünün Sürdürülebilirlik raporlarında yer alan “Sürdürülebilirlik İlkelerini” hedef kitle iletişiminde nasıl kullandığının incelenmesi amaçlanmaktadır. Sürdürülebilir halkla ilişkiler anlayışında paydaş katılımı ve desteği açısından sosyal medya kullanımı giderek önem kazanmaktadır. Hootsuite ve We Are Social 2021 Dijital Türkiye Raporuna göre 2021 yılında Türkiye’de en çok kullanılan sosyal medya platformu YouTube olarak karşımıza çıkmaktadır. Buradan hareketle çalışmada Küresel Raporlama Girişimi (Global Reporting Initiative-GRI) İlkeleri’ne göre sürdürülebilirlik raporunu yayınlayan ilk Türk mevduat bankası olan Akbank’ın 2021 yılı YouTube içerikleri, dokümantasyon tarama yöntemiyle incelenerek bir vaka çalışması yapılmıştır. Araştırma sonucunda bankanın YouTube içeriklerinde sürdürülebilirlik raporlarında yer alan ilkelere yönelik projelere yer verdiği görülmekle birlikte, hesabın yorumlara kapalı olması paydaş katılımını sınırlayıcı bir unsur olarak yorumlanmıştır.
Aplicação da Lei de Stokes: um experimento didático em Fenômenos de Transporte
Authors: Siqueira Antonio Marcos de Oliveira , Khechekhouche Abderrahmane , Campos Júlio Cesar Costa , Silva Gabriel Siqueira , Cruz Marlons Lino da 
Published: April 2022

Este trabalho teve como objetivo contribuir com estudos sobre a elaboração e a implementação de propostas de atividade didática baseada em experimento de cunho investigativo. O trabalho descreve um experimento com fins acadêmicos para a determinação da massa específica e da viscosidade dinâmica de um fluido por meio do Método de Stokes, um procedimento experimental simples e de baixo custo e que possibilita o processo de ensino/aprendizagem de conceitos diversos da área de Mecânica dos Fluidos, aplicada ao campo da Engenharia. Os valores obtidos de massa específica - (899,60 ± 18,00) kg/m3, (996,00 ± 19,93) kg/m3 e (1.298,00 ± 25,97) kg/m3 - e da viscosidade dinâmica - (0,080 ± 0,001) Pa.s, (0,649 ± 0,007) Pa.s e (0,885 ± 0,015) Pa.s, respectivamente para os fluidos óleo vegetal refinado de soja, detergente e glicerina foram próximos dos valores encontrados na literatura e apresentaram baixo grau de incerteza propagada. O desenvolvimento desta implementação foi realizado com apoio do software EES e apresenta-se como uma proposta de atividade didática baseada em experimento de cunho investigativo em Mecânica dos Fluidos.
Os problemas recentes e as muitas virtudes do Mercado de trabalho para profissionais de Relações Internacionais no Brasil
Authors: Lessa Antônio Carlos 
Published: April 2022

Dada grande expansão recente dos cursos de Relações Internacionais no Brasil, a presente análise tem como foco expor as distintas possibilidades de atuação do profissional de Relações Internacionais no mercado de trabalho.
Identification of Safe Channels for Screws in the Anterior Pelvic Ring Fixation System
Authors: Liu Lin , Fan Shicai , Zeng Donggui , Song Hui , Zeng Letian , Wen Xiangyuan , Jin Dadi 
Published: April 2022

Abstract
Background: There have been few studies on insertion of fixation screws for the anterior pelvic ring system. Objective: To identify safe channels for fixation screws in the anterior pelvic fixation system. |Methods: Screw insertion was simulated into a total of 40 pelvic finite element models as well as 16 fresh pelvic specimens and the channel parameters were measured. Results: Finite elements (male, female): screws in ilium: length 114.4 ± 4.1 and 107.6 ± 8.3 mm, respectively; diameter 11.7 ± 0.5 and 10.0 ± 0.6 mm, distance between screw and anterior inferior iliac spine: 5.5 ± 1.0 and 5.6 ± 1.0 mm, angle of coronal plane 55.8 ± 2.4 degrees and 50.6 ± 3.1 degrees, angle of sagittal plane 26.6 ± 1.0 degrees and 24.5 ± 1.9 degrees and angle of horizontal plane 64.9 ± 3.7 and 58.1 ± 3.1. Screws in pubis: length 47.0 ± 2.0 and 39.8 ± 3.9 mm, diameter 7.1 ± 0.4 and 6.1 ± 0.4 mm. Specimens (male, female): distance between screw and anterior inferior iliac spine: 5.5 ± 0.5 and 5.6 ± 0.7 mm, angle of coronal plane 55.9 ± 1.3 degrees and 50.7 ± 1.5 degrees, angle of sagittal plane 26.7 ± 0.5 degrees and 24.1 ± 0.9 degrees and angle of horizontal plane 64.8 ± 0.6 degrees and 58.8 ± 0.8 degrees. Comparison between female and male in each group: differences in distances between screws and anterior inferior iliac spine and median line of symphysis pubis (P > 0.05) were not statistically significant; differences in the remaining parameters were statistically significant (P < 0.05). Conclusions: If surgeons payed attention to sex differences, select screws of appropriate diameter and length, and hold the insertion position and direction, screws in the anterior pelvic ring fixation system could be safely inserted.