bluuebunny/crossref_metadata_2025_split huggingface dataset:
Children in marketing: A review, synthesis and research agenda
Authors: Sigirci Ozge , Gegez A. Ercan , Aytimur Hilal , Gegez E. Eser 
Published: April 2022

AbstractChildren have received much research attention in many different academic disciplines within social sciences, including marketing. The main objective of this study is to provide a comprehensive overview of the marketing literature to investigate the historical evolution of the studies on “children” and shed light on possible gaps which could serve as new research areas for future studies. To the authors' best knowledge, there have been a few attempts on the topic, mostly with a narrow focus on only some aspects of this important concept. The significance of this current research is that it reviews 423 articles from marketing‐related journals and evaluates the development of thought on “children” from every marketing‐based perspective that once has been a subject of scholarly attention. In this study, we examined leading articles, authors and institutions, methodologies used, countries data collected from, and the age of the sample. In addition, an auto‐correlation map is created to identify all the research domains in marketing literature related to children. Our correlation matrix indicates that major subareas in children and marketing literature are children's consumer socialization and role in family decision‐making, materialism, vulnerability and ethics, food, brands, and advertising. Findings revealed that while marketing scholars have shown great attention to children during the last two decades and a wide array of articles have been frequently published on the eight sub‐areas mentioned, marketing literature is still underdeveloped on three aspects: sustainability, technology and digitalization, and cross‐cultural differences.
Changes in virus detection in hospitalized children before and after the severe acute respiratory syndrome coronavirus 2 pandemic
Authors: Kume Yohei , Hashimoto Koichi , Chishiki Mina , Norito Sakurako , Suwa Reiko , Ono Takashi , Mochizuki Izumi , Mashiyama Fumi , Ishibashi Naohisa , Suzuki Shigeo , Sakuma Hiroko , Takahashi Hitoshi , Takeda Makoto , Shirato Kazuya , Hosoya Mitsuaki 
Published: April 2022

AbstractThe impact of strengthening preventive measures against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection on the prevalence of respiratory viruses in children was examined. After the SARS‐CoV‐2 pandemic, the rate of multiple virus detection among hospitalized children decreased. Immediately after the SARS‐CoV‐2 pandemic, respiratory syncytial and parainfluenza viruses were rarely detected and subsequently reemerged. Human metapneumovirus and influenza virus were not consistently detected. Non‐enveloped viruses (bocavirus, rhinovirus, and adenovirus) were detected to some extent even after the pandemic. Epidemic‐suppressed infectious diseases may reemerge as susceptibility accumulates in the population and should continue to be monitored.
Effect of properties and crystallization behavior of BaO–ZnO–B2O3–SiO2 glass on the electrical conductivity of Cu paste
Authors: Chen Yijing , Li Jiacheng , Jiang Qi , Li Ao , Yu Jia , Zeng Huidan 
Published: April 2022

AbstractThe extensive application of multilayer ceramic capacitors provides an attractive development for terminal electrode pastes. However, the growing requirement for advanced glass materials used in terminal electrode pastes is substantiated. Therefore, to advance the development of electrode pastes, better development and deeper exploration of glass powder are required. Here, a series of BaO–ZnO–B2O3–SiO2 (BZBS) glasses were prepared by melt‐quenching technique, which are used to investigate the effect of the introduction of BaO on structure and properties of the ZnO–B2O3–SiO2 (ZBS) glass. With the introduction of BaO, the relative amount of [BO4] was much less, which made the glass network structure loosen, decreased the glass transition temperature (Tg) and increased the coefficient of thermal expansion of the glass. The decreasing contact angle was observed on the surface of a barium titanate (BaTiO3) substrate. When the BaO content was around 3–7 mol%, the stability of ZBS glass frit could be strengthened by inhibiting the precipitation of Zn2SiO4 crystal. In addition, to further characterize the effect of glass on terminal electrode paste, BZBS glass powder was adopted to prepare copper electrode paste, which was printed on the BaTiO3 substrate and subsequently fired at 800°C for 10 min. With the related copper paste containing ZBS glass doped with 7 mol% BaO, the optimum value of acid resistance and sheet resistance (1.99 mΩ) were exhibited, at which the coated copper paste formed a dense conducting layer.
A joint distribution framework to improve presence‐only species distribution models by exploiting opportunistic surveys
Authors: Escamilla Molgora Juan M. , Sedda Luigi , Diggle Peter , Atkinson Peter M. 
Published: April 2022

AbstractAimThe availability of data related to species occurrences has favoured the development of species distribution models using only observations of presence. These data are intrinsically biased by the sampling effort. Presence‐only (PO) species distribution models (SDM) typically account for this effect by introducing additional data considered to be related with the sampling. This approach, however, does not allow the characterisation of the sampling effort and hinders the interpretation of the model. Here, we propose a Bayesian framework for PO SDMs that can explicitly model the sampling effect.LocationMexico.TaxonPines, flycatchers (family Tyranidae), birds and plants.MethodsThe framework defines a bivariate process separable into ecological and sampling effort processes. PO data are conceived of incomplete observations where some presences have been filtered out. A choosing principle is used to separate out presences, missing data and absences relative to the species of interest and the sampling observations. The framework provides three modelling alternatives to account for a spatial autocorrelation structure: independent latent variables (model I); common latent spatial random effect (model II) and correlated latent spatial random effects (model III). The framework was compared against the Maximum Entropy (MaxEnt) algorithm in two case studies: one for the prediction of pines and another for the prediction of flycatchers.ResultsIn both case studies, at least one of the proposed models achieved higher predictive accuracy than MaxEnt. The model III fit best when the sampling effort was informative, while model II was more suitable in cases with a high proportion of non‐sampled sites.Main ConclusionsOur approach provides a flexible framework for PO SDMs aided by a sampling effort process informed by the accumulated observations of independent and heterogeneous surveys. For the two case studies, the framework provided a model with a higher predictive accuracy than an optimised version of MaxEnt.
Clinical outcomes of left bundle branch area pacing compared to His bundle pacing
Authors: Vijayaraman Pugazhendhi , Rajakumar Clement , Naperkowski Angela M. , Subzposh Faiz A. 
Published: April 2022

AbstractIntroductionHis bundle pacing (HBP) is the most physiologic form of pacing and has been associated with reduced risk for heart failure hospitalization (HFH) and mortality compared to right ventricular pacing. Left bundle branch area pacing (LBBAP) is a safe and effective alternative option for patients needing ventricular pacing. The aim of this study was to compare the clinical outcomes between LBBAP and HBP among a large cohort of patients undergoing permanent pacemaker implantation.MethodsThis observational registry included consecutive patients with AV block/AV node ablation who underwent de novo permanent pacemaker implantations with successful LBBAP or HBP between April 2018 and October 2020. The primary outcome was the composite endpoint of time to death from any cause or HFH. Secondary outcomes included the composite endpoint among patients with prespecified ventricular pacing burden and individual outcomes.ResultsThe study population included 359 patients who met the inclusion criteria (163 in the HBP and 196 in the LBBAP group). Paced QRSd during LBBAP was similar to HBP (125 ± 20.2 vs. 126 ± 23.5 ms, p = .643). There were no statistically significant differences in the primary composite outcome in LBBAP (17.3%) compared to HBP (24.5%) (hazard ratio [HR]: 1.15, 95% CI: 0.72–1.82, p = .552). Secondary outcomes of death (10% vs. 17%; HR: 1.3, 95% CI: 0.73–2.33, p = .38) and HFH (10% vs. 12%; HR: 1.02, 95% CI: 0.54–1.94, p = .94) were not different among both groups.ConclusionsThere were no statistically significant differences in the clinical outcomes of death or HFH in LBBAP when compared to HBP.
Initial clinical experience of pulmonary vein isolation using the ultra‐low temperature cryoablation catheter for patients with atrial fibrillation
Authors: Tohoku Shota , Schmidt Boris , Bordignon Stefano , Chen Shaojie , Bologna Fabrizio , Chun Julian Kyoung‐Ryul 
Published: April 2022

AbstractBackgroundThe iCLAS ultra‐low temperature cryoablation (ULTC) system has recently been brought to the market. A combination of a newly exploited cryogen and interchangeable stylet enables flexible and continuous lesion creation in atrial fibrillation (AF) ablation. The use of an esophageal warming balloon is recommended when using the system to reduce the potential for collateral esophageal injury.ObjectiveTo describe the initial clinical experience when using ULTC in the AF treatment without general anesthesia (GA).MethodsConsecutive patients undergoing AF ablation using ULTC under deep sedation without GA were enrolled. We assessed the procedural data focusing on “single‐shot isolation” defined as successful pulmonary vein (PV) isolation after the first application. Esophagogastroduodenoscopy was systematically performed the day after ablation.ResultsA total of 27 AF patients (67% paroxysmal AF) were analyzed. Onehundred four out of 106 PVs (98.1%) were isolated solely using ULTC. The mean procedure time was 79 ± 30 min. The mean number of applications per PV was 2.6 ± 1.0. Single‐shot isolation was achieved in 57 PVs (54%) varying across PVs from left superior to inferior PVs (40%–64%). The single procedure 6‐month recurrence‐free rate was 84%. No major complication (cerebrovascular event, pericardial effusion/tamponade, esophageal damage on esophagogastroduodenoscopy) occurred. A single transient phrenic nerve palsy occurred during the right superior PV ablation, which had recovered by the 3‐month follow‐up appointment.ConclusionsAF ablation using the novel ULTC system seemed feasible without GA and enabled a >50% single‐shot isolation rate. The promising safety profile has to be confirmed in large‐scale studies.
Differences of blood pressure measured at clinic versus at home in the morning and in the evening in Europe and Asia: A systematic review and meta‐analysis
Authors: Miao Huanhuan , Yang Shijie , Zhang Yuqing 
Published: April 2022

AbstractNumerous studies have indicated that there might be great differences among different populations in Europe and Asia in terms of home morning and evening blood pressure (BP). Thus, the authors performed a systematic review to determine the quantitative differences of BP measured at clinic versus at home in the morning and in the evening in Europe and Asia. PubMed, Embase, and Scopus databases were searched up to October 2021. Studies that compared clinic BP with home morning and (or) home evening BP in European and Asian populations were included. A random effect model was applied to pool the differences between clinic BP and home morning/evening BP. Thirty‐five studies, for a total of 49 432 patients, were included in this meta‐analysis. Mean clinic systolic blood pressure (SBP) values were significantly higher than home morning SBP values by 3.79 mmHg (95% CI, 2.77–4.80). The differences were much larger in Europe [(6.53 mmHg (95% CI, 4.10–8.97)] than in Asia [(2.70 mmHg (95% CI, 1.74–3.66)], and the region was a significant predictor for the differences. Mean clinic SBP values were also significantly higher than home evening SBP values by 6.59 mmHg (95% CI, 4.98–8.21). The differences were much smaller in Europe [5.85 mmHg (95% CI, 3.24–8.45)] than in Asia [7.13 mmHg (95% CI, 4.92–9.35)], while age and clinic SBP might contribute to it. Our findings showed that the difference between clinic and home morning SBP was much larger in European than Asian populations, whereas the difference between clinic and home evening SBP was the opposite. The differing characteristics of the region, ethnic, age, and clinic BP might explain the diversities.
Does judicial foreclosure procedure help delinquent subprime mortgage borrowers?
Authors: Ding Aidong Adam , Tian Shaonan , Yu Yan , Zhao Xinlei 
Published: April 2022

AbstractWe conduct comprehensive analyses on whether and how the judicial foreclosure procedure helps subprime mortgage borrowers to reinstate their delinquent loans outside foreclosure liquidation. Even though the transition rates of various exit types are all higher in non‐judicial states, we argue such higher rates can be mechanically driven by the faster shrinking pool of delinquent mortgages in non‐judicial states over time. Based on the cumulative proportions of various exit types during a period of up to 5 years post the mortgage first become 90 days past due, we find that judicial states offer more opportunities for delinquent borrowers to reinstate their loans outside foreclosure liquidation, especially during a housing market downturn. Cures, modifications, and paid‐offs were all important alternative ways to resolve serious delinquencies during 2007–2008. After modifications became widely available in 2009, loan modifications became the most important alternative for subprime borrowers to reinstate their delinquent mortgages outside foreclosure liquidation. The lion's share of the judicial foreclosure benefit shows up after the start of the foreclosure process.
Fragmentation of care in the last year of life: Does dementia status matter?
Authors: Nothelle Stephanie , Kelley Amy S. , Zhang Talan , Roth David L. , Wolff Jennifer L. , Boyd Cynthia 
Published: April 2022

AbstractBackgroundCare at the end of life is commonly fragmented; however, little is known about commonly used measures of fragmentation of care in the last year of life (LYOL). We sought to understand differences in fragmentation of care by dementia status among seriously ill older adults in the LYOL.MethodsWe analyzed data from adults ≥65 years in the National Health and Aging Trends Study who died and had linked 2011–2017 Medicare fee‐for‐service claims for ≥12 months before death. We categorized older adults as having serious illness due to dementia (hereafter dementia), non‐dementia serious illness or no serious illness. For outpatient fragmentation, we calculated the Bice–Boxerman continuity of care index (COC), which measures care concentration, and the known provider of care index (KPC), which measures the proportion of clinicians who were previously seen. For acute care fragmentation, we divided the number of hospitals and emergency departments visited by the total number of visits. We built separate multivariable quantile regression models for each measure of fragmentation.ResultsOf 1793 older adults, 42% had dementia, 53% non‐dementia serious illness and 5% neither. Older adults with dementia had fewer hospitalizations than older adults with non‐dementia serious illness but more than older adults without serious illness (mean 1.9 vs 2.3 vs 1, p = 0.002). In adjusted models, compared to older adults with non‐dementia serious illness, those with dementia had significantly less fragmented care across all quantiles of COC (range 0.016–0.110) but a lower predicted 90th percentile of KPC, meaning more older adults with dementia had extremely fragmented care on the KPC measure. There was no significant difference in acute care fragmentation.ConclusionsIn the LYOL, older adults with dementia have fewer healthcare encounters and less fragmentation of care by the COC index than older adults with non‐dementia serious illness.
Assessing the frequency of adverse reactions induced by melanin‐containing formulations used for the management of solar dermatitis
Authors: Petrosyan Tigran R. , Nameq Rozh A. 
Published: April 2022

AbstractBackgroundMelanin from different sources is widely used by many manufacturers to produce cosmetics and sunscreens. Research data show a wide spectrum of biological activities of melanin including the protection against UV radiation and oxidants. According to the research evidence, the topical use of melanin is more effective against inflammation than the hydrocortisone. The most common side effects of topical melanin ointment are local itching, burning, and moderate hyperemia.Aim of the studyThe purpose of this work is to describe the adverse outcomes of melanin‐containing formulas in patients with solar dermatitis, and to compare the frequency of adverse reactions with data from different research reports.MethodsA Pharmacovigilance questionnaire was developed to assess potential adverse events attributable to the use of melanin ointment. We used a modified survey tool created by Jaber and coauthors. This survey of melanin application documents validated reports of adverse events manifested by objective skin changes. MEDLINE (Ovid); MEDLINE In‐Process Citations & Daily Update (Ovid); PubMed (NLM) (Internet); Embase (Ovid); and Cochrane Database of Systematic Reviews were searched for the evidence on adverse reactions of topical melanin application.ResultsThe responses documented in this survey show reliability and safety of melanin formula used for the photoprotection and treatment of solar dermatitis. Most symptoms encountered in those using melanin were consistent with exposure to excessive amount (more than 4 times per day) of the compound applied topically. Of the total 534 survey responses received, 74% reported no adverse events. A total of 140 completed adverse event reports. Melanin ointment was being administered for the indications of photo injury (burns) in 75%, photodermatitis in 18%, and solar eczematous dermatitis in 7% of patients. Data were compared with rates from other reports.ConclusionWe have no evidence that the chemical structure of melanin varies with currently available products, used locally or in other countries, nor that any such variability played any role in the events reported here. Further studies are required to compare the adverse events of topical melanin formulas containing melanins of different origin.
Medical cannabis and stigma: A qualitative study with patients living with chronic pain
Authors: Hulaihel Amany , Gliksberg Or , Feingold Daniel , Brill Silviu , Amit Ben H. , Lev‐ran Shaul , Sznitman Sharon R. 
Published: April 2022

AbstractAims and ObjectivesTo explore the ways in which stigma is experienced, and what strategies are used to manage stigma among patients using medical cannabis to ease suffering from chronic pain.BackgroundVarious jurisdictions have legalised medical cannabis in recent decades. Despite increasing prevalence and more liberal attitudes towards medical cannabis, it is possible that patients who use medical cannabis experience stigma.DesignA phenomenological qualitative study.MethodsFifteen patients living with chronic pain and licensed by the Israeli Ministry of Health to use medical cannabis to treat pain symptoms for at least 1 year participated in semi‐structured interviews. Transcribed data were analysed using thematic analysis to identify themes related to stigma. The manuscript is in correspondence to SRQR EQUATOR checklist.ResultsExpressions of stigma were more related to ‘felt’ than ‘enacted’ stigma. Stigma related to decisions to delay onset of medical cannabis treatment and the ways in which participants managed medical cannabis use during their everyday lives. Participants dissociated themselves from recreational cannabis users, by presenting themselves as responsible normative individuals and engaging in a form of normalisation known as ‘normification’, emphasising their own discrete and controlled medical cannabis use and cannabis' benefits.ConclusionsPatients experienced ‘felt’ stigma which had consequences for their self‐presentations and medical cannabis use. This suggests that medical cannabis is not normalised in Israel and interventions may be needed to handle stigma related to medical cannabis.Relevance to clinical practiceThe findings emphasise the effects of ‘felt’ stigma on patients. Aiming to increase the effectiveness of medical cannabis treatment and reducing harms, we suggest that particular focus should be placed on managing stigma at the intrapersonal level. In addition, there may be a need to address stigma at the societal level including social interactions with friends, family and medical personnel.
Recurrent copy number alterations involving EGFR, CDKN2A, and CCND1 in oral premalignant lesions
Authors: Jäwert Fredrik , Fehr André , Öhman Jenny , Stenman Göran , Kjeller Göran 
Published: April 2022

AbstractBackgroundA major challenge in the management of patients with oral leukoplakia is the difficulty to identify patients at high risk of developing oral squamous cell carcinoma. Our knowledge about genomic alterations in oral leukoplakia, and in particular those that progress to oral squamous cell carcinoma, is scarce and there are no useful biomarkers that can predict the risk of malignant transformation.MethodsUsing a novel, custom‐made tissue microarray including 28 high‐risk oral leukoplakias and the corresponding oral squamous cell carcinomas from 14 cases that progressed to cancer, we assayed copy number alterations involving the oral squamous cell carcinoma driver genes CDKN2A, CCND1, EGFR, and MYC by fluorescence in situ hybridization. The copy number alterationss were correlated with clinicopathological data from all patients.ResultsCopy number alterations were identified in 14/24 oral leukoplakias, analyzable for one or more of the oral squamous cell carcinoma driver genes. EGFR was the most frequently altered gene in oral leukoplakias with amplification/gain in 43.5% followed by loss of CDKN2A (26.1%), gains of CCND1 (26.1%), and MYC (8.3%). Losses of CDKN2A were more common in oral leukoplakias progressing to oral squamous cell carcinoma compared to those that did not. Copy number alterations were more common in oral squamous cell carcinomas than in oral leukoplakias.ConclusionsOur findings demonstrate that copy number alterations involving the oral squamous cell carcinoma drivers CDKN2A, EGFR, and CCND1 occur in oral leukoplakias and suggest a possible role for these genes in the development and/or progression of subsets of oral leukoplakias.