bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tolerance for three commonly administered COVID-19 vaccines by healthcare professionals
Authors: Melanson Stacy E. F. , Zhao Zhen , Kumanovics Attila , Love Tanzy , Meng Qing H. , Wu Alan H. B. , Apple Fred , Ondracek Caitlin R. , Schulz Karen M. , Wiencek Joseph R. , Koch David , Christenson Robert , Zhang Y. Victoria 
Published: September 2022

ImportanceMost healthcare institutions require employees to be vaccinated against SARS-CoV-2 and many also require at least one booster.ObjectiveWe determine the impact of vaccine type, demographics, and health conditions on COVID-19 vaccine side effects in healthcare professionals.DesignA COVID-19 immunity study was performed at the 2021 American Association for Clinical Chemistry Annual Scientific meeting. As part of this study, a REDCap survey with cascading questions was administered from September 9, 2021 to October 20, 2021. General questions included participant demographics, past and present health conditions, smoking, exercise, and medications. COVID-19 specific questions asked about SARS-CoV-2 vaccine status and type, vaccine-associated side effects after each dose including any boosters, previous infection with COVID-19, diagnostic testing performed, and type and severity symptoms of COVID-19.ResultsThere were 975 participants (47.1% male, median age of 50 years) who completed the survey. Pfizer was the most commonly administered vaccine (56.4%) followed by Moderna (32.0%) and Johnson &amp; Johnson (7.1%). There were no significant differences in vaccine type received by age, health conditions, smoking, exercise, or type or number of prescription medications. Side effects were reported more frequently after second dose (e.g., Moderna or Pfizer) (54.1%) or single/only dose of Johnson &amp; Johnson (47.8%). Males were significantly more likely to report no side effects (p &lt; 0.001), while females were significantly more likely to report injection site reactions (p &lt; 0.001), fatigue (p &lt; 0.001), headache (p &lt; 0.001), muscle pain (p &lt; 0.001), chills (p = 0.001), fever (p = 0.007), and nausea (p &lt; 0.001). There was a significant upward trend in participants reporting no side effects with increasing age (p &lt; 0.001). There were no significant trends in side effects among different races, ethnicities, health conditions, medications, smoking status or exercise. In multivariate logistic regressions analyses, the second dose of Moderna was associated with a significantly higher risk of side effects than both the second dose of Pfizer and the single dose of Johnson &amp; Johnson.Conclusions and relevanceYounger people, females, and those receiving the second dose of Moderna had more COVID-19 vaccine side effects that per self-report led to moderate to severe limitations. As reported in other studies, the increase in side effects from Moderna may be explained by higher viral mRNA concentrations but be associated with additional protective immunity.
Bibliometric analysis of human monkeypox research from 1975 to 2022 and novel prevention and control strategies
Authors: Lin Jiyong , Li Guiyu , Zhong Peiling , Zeng Qiang , Liu Lei , Chen Liang 
Published: September 2022

BackgroundSince human monkeypox was reported, many related literatures have been published. This study aimed to evaluate the research hotspots and future development trends of human monkeypox by a bibliometric analysis, to analyze the preventive and control measures of various countries in response to human monkeypox outbreaks.MethodsThe Web of Science Core Collection database was searched for all monkeypox related literature published from 1975 to 2022, and the search strategy was “TS = monkeypox.” Bibliometric analysis was performed using VOSviewer software based on retrieval data. Contribution metric methods and visualization were used to analyze the top issues in the field of human monkeypox.ResultsFrom 1975 to 2022, a total of 1,068 monkeypox research papers were included, of which American researchers published 663 papers, and it was also the country that participated in the most international cooperation. Centers for Disease Control Prevention USA is the most prolific institution and a leader in research collaborations. The Journal of Virology has the largest number of published papers on monkeypox. In addition, Damon Inger K has made significant contributions to monkeypox research, with both the most published and the most citation. A total of 2,847 keywords were identified, four top topics were obtained through cluster analysis: (1) human monkeypox epidemiology and species research. (2) human monkeypox virus vaccine and experimental research. (3) human monkeypox disease diagnosis and treatment studies. (4) human monkeypox disease prevention and immunization studies. To curb the spread, regions or countries have developed and implemented detailed managements. The prevention and control measures focus on the isolation of suspected or confirmed patients, the investigation and tracking of the source of the disease, the disposal of pollutants, vaccination and the protection of health workers.ConclusionsThe number of human monkeypox literature has grown since 2003. Infection, vaccine and efficacy were the top topic over the past 47 years while the contact tracing, testing, surveillance and vaccination have been the major concerns since the human monkeypox outbreak in May 2022. The treatment and management of human monkeypox deserves further attention.
High-quality facial-expression image generation for UAV pedestrian detection
Authors: Tang Yumin , Fan Jing , Qu Jinshuai 
Published: September 2022

For UAV pedestrian detection in the wild with perturbed parameters, such as lighting, distance, poor pixel and uneven distribution, traditional methods of image generation cannot accurately generate facial-expression images for UAV pedestrian detection. In this study, we propose an improved PR-SGAN (perceptual-remix-star generative adversarial network) method, which combines the improved interpolation method, perceptual loss function, and StarGAN to achieve high-quality facial-expression image generation. Experimental results show that the proposed method for discriminator-parameter update improves the generated facial-expression images in terms of image-generation evaluation indexes (5.80 dB in PSNR and 24% in SSIM); the generated images for generator-parameter update have high robustness against color. Compared to the traditional StarGAN method, the generated images are significantly improved in high frequency details and textures.
A clinical observational study on the application of enhanced recovery after laparoscopic pancreaticoduodenectomy
Authors: Liao Rui , Li Jun-Cai , Chen Jie , Wei Xu-Fu , Yan Xiong 
Published: September 2022

PurposeThe safety and feasibility of enhanced recovery after surgery (ERAS) for laparoscopic pancreaticoduodenectomy (LPD) are unclear. The aim of this retrospective clinical study was to evaluate the impact of ERAS protocols for LPD.Patients and methodsBetween March 2016 and December 2018, a total of 34 consecutive patients with ERAS for LPD were prospectively enrolled and compared with 68 consecutive patients previously treated for non-ERAS after LPD during an equal time frame. The intraoperative and postoperative data were collected and comparatively analyzed.ResultsThe mean length of postoperative hospital stay (15.8 ± 3.4 and 23.1 ± 5.1 days, P &lt; 0.001) was reduced significantly in ER group than those in non-ER group. The operation time (462.7 ± 117.0 vs. 450.9 ± 109.8 min, P = 0.627) and intraoperative blood loss (523.5 ± 270.0 vs. 537.5 ± 241.8 ml, P = 0.800) were similar in the two groups. The complications (ER: 32.4% vs. non-ER: 35.3%, P &gt; 0.05) and their severities (Clavien–Dindo grade ≥3 complications, 2 vs. 5 patients; P = 0.783) of patients with ERAS protocols were not increased. No difference in mortality and readmission rates was found. Finally, the total medical costs ($2.1 ± 0.7 × 104 and $2.3 ± 0.7 × 104, P = 0.017) in ER group were lower than those in non-ER group.Conclusionthe ERAS is safe and effective in the perioperative period of LPD. It could effectively reduce the length of postoperative stay and medical costs, and does not increase the incidence of postoperative complications.
Minimally Invasive Tensiometry: A New Modality for Per-Operative Measurement of Medialization and Tension During Laparoscopic Hernia Surgery
Authors: Den Hartog F. P. J. , Van Koten E. F. , Van Den Dobbelsteen J. J. , Tanis P. J. , Van Der Elst M. , Bloemendaal A. L. A. 
Published: September 2022

Background: Newly developed techniques for minimally invasive abdominal wall reconstruction (AWR) for complex ventral hernia are continuously evolving. In order to achieve hernia defect closure, the aponeurotic edges of the hernia defect need to be approximated. Currently, surgeons have no way to objectively measure and quantify the traction required to approximate these edges. This study presents minimally invasive tensiometry (MINT), a novel technology for measuring fascial tension, as well as initial experiences and results using it.Methods: The MINT device was designed using rapid prototyping principles. It was designed as an add-on tool for any existing laparoscopic instrument, enabling objective assessment of abdominal wall tension by the use of a manually operated linear spring. Pre-clinical measurements of medialization at 10 and 20 N of tension during AWR were performed on fresh-frozen Post-Mortem Human Specimens (PMHS).Results: Three specimens were included, and a total number of 36 measurements of medialization at three different levels of the abdominal wall were performed under structured and similar circumstances. Median total medialization with 20 Newton (N) of applied tension was 25 mm (mm) cranially, 37.5 mm at the umbilicus and 27.5 mm at the caudal level. The highest rate of medialization was seen at the umbilical level (2.25 mm/N).Conclusion: MINT is a novel non-invasive technique, which allows surgeons to intraoperatively measure fascial tension when performing AWR. The MINT device is easy to use and reproduce. The next step is to start performing clinical measurements applying MINT during AWR.
An interrupted time-series analysis of the effects of withdrawal of financial incentives on diagnosis of atrial fibrillation as resolved. Does withdrawal of an incentive reverse its unintended effects?
Authors: Quinn Laura , Hosier Isaac , Adderley Nicola Jaime , Marshall Tom 
Published: September 2022

BackgroundThe UK introduced financial incentives for management of atrial fibrillation (AF) in 2006, after which there was an increase in the proportion of patients with AF diagnosed as resolved. Removal of incentives in Scotland provides a natural experiment to investigate the effects of withdrawal of an incentive on diagnosis of resolved AF.AimTo investigate the effects of introduction and withdrawal of financial incentives on the diagnosis of resolved AF.Design & settingCohort study in a large database of UK primary care records, before and after introduction of incentives in April 2006 in Scotland, England, and Northern Ireland, and their withdrawal in April 2016 in Scotland.MethodInterrupted time-series analysis of monthly rates of resolved AF from January 2000–September 2019.ResultsA total of 251 526 adult patients with AF were included, of whom 14 674 were diagnosed as resolved AF. In April 2006 there were similar shift-changes in rates of resolved AF per 1000 in England 1.55 (95% confidence interval [CI] = 1.11 to 2.00) and Northern Ireland 1.54 (95% CI = 0.91 to 2.18), and a smaller increase in Scotland 0.79 (95% CI = 0.04 to 1.53). There were modest downward post-introduction trends in all countries. After Scotland’s withdrawal of the incentive in April 2016 there was a small, statistically non-significant, downward shift in rate of resolved AF per 1000 (0.39 [95% CI = -3.21 to 2.42]) and no change in post-removal trend.ConclusionIntroduction of a financial incentive coincided with an increase in resolved AF but no evidence was found that its withdrawal led to a reduction.
Exploring the Economic Aspects of β-Thalassemia in Jordan in 2019
Authors: Alabbadi Ibrahim , Massad Eman , Taani Nashaat , Dababneh Safwan , Shersheer Qasem , Nimri Omar , Mahmoud Refqi , Hijazeen Rami , Ishaq Adnan 
Published: September 2022

Thalassemia are inherited hematological disorders considered among the most common genetic disorders worldwide, occurring more frequently in the Mediterranean Region. The WHO estimates that Beta-thalassemia affects 2.9% of the world’s population. In Jordan, the carrier prevalence rate of thalassemia is from 2-4%. Patients with thalassemia need a lifelong care, devastating their quality of life and imposing overwhelming psychological and financial burden on patients and their families. The Jordanian Ministry of Health (MOH) is the sole facility responsible for treating these patients from the pre-marital program until required medications regardless of their nationality. This study aimed to estimate the economic burden of thalassemia in Jordan in 2019. All 680 thalassemia patients admitted to thalassemia centers in Jordan and coming to out-patients’ clinics from July 1st to Aug 31st, 2019 are included. Data were collected using a pre-developed questionnaire from the electronic medical records. The economic burden was estimated from MOH perspective and societal perspective. The average annual cost was estimated to be 2,674 JOD for a single thalassemia Jordanian insured patient and 4,627 JOD for un-insured, while the non-Jordanian patient’ annual cost was estimated 4,751 JOD if insured and 6,651 JOD if un-insured. The total economic burden of thalassemia in Jordan in 2019 was estimated to be 2,148,741 JOD. Of this amount, 1,393,329 JOD was for Jordanians and 755,412 JOD for non-Jordanians. In conclusion, this high burden of thalassemia in Jordan requires adopting new controlling policies; pre-marriage counseling, education and raising awareness should be encouraged.
Aplikasi Pedagang Sayur Untuk Daftar Harga Bahan Pangan Subsistem Aplikasi Android Untuk Pedagang
Authors: Sunardi  , Bertaqwa Addin Gama , Sofian MZ Dedy 
Published: September 2022

Abstract: All economic operations disturbed by technological centers or traditional markets during the Covid-19 epidemic will benefit from the development of this information or information system capable of supporting business activities in every line of life. A vegetable trader's work entails selling items such as vegetables, meat, fish, and other items that are frequently sought after by the community to meet their daily dietary requirements. Traders have significant challenges due to the limited number of market visitors and the rapid decay of merchandise. The goal of this research is to create a mobile veggie application utilizing the React Native framework and the Waterfall approach to design Android-based applications that are simple to use. Customers can order via Whatsapp since it is simpler and easier to follow up, and the majority of customers must be familiar with Whatsapp. Customers can examine prices, types/categories, and place orders via the app, which is an android-based application.
Keywords: Vegetable seller; Android; Waterfall
Abstrak: Berkembangnya teknologi informasi atau sistem informasi saat ini telah mampu mendukung kegiatan bisnis pada setiap lini kehidupan hal tersebut menjadi faktor pembantu saat segala proses ekonomi terganggu oleh pembatasan kerumunan pada pusat perbelanjaan atau pasar tradisional selama masa pandemi Covid-19. Pedagang sayur adalah sebuah pekerjaan yang menjual barang dagangan seperti sayuran, daging, ikan, dan lain-lain yang dagangannya seringkali dicari oleh masyarakat untuk memenuhi kebutuhan bahan pangan sehari – hari. Rendahnya jumlah pengunjung pasar dan cepat membusuknya bahan dagangan menjadi masalah besar bagi pedagang. Tujuan dari penelitian ini adalah membangun suatu aplikasi sayur mobile menggunakan framework React Native untuk mengembangkan aplikasi berbasis Android dengan menggunakan metode Waterfall, sehingga aplikasi yang dibangun mudah digunakan. Hasil dari penelitian ini adalah aplikasi berbasis android untuk memudahkan pedagang menambahkan data dagangan karena mayoritas sudah memiliki hp android, pelanggan bisa memesan melalui Whatsupp karena lebih simple dan mudah di follow up, mayoritas pelanggan pasti sudah familiar dengan Whatsupp, Customer bisa melihat harga, jenis/kategori melakukan pesanan via app.
Kata kunci: Pedagang Sayur; Android; Waterfall.
Gallium-nitride-based interference-filter-stabilized external cavity diode laser with a surface-activated-bonded output coupler
Authors: Ogawa Hisashi , Kemmochi Tatsuya , Takano Tetsushi 
Published: September 2022

Abstract
We report on an interference-filter-stabilized external cavity diode laser (ECDL) using a gallium-nitride-based violet laser diode. Surface-activated-bonded glass substrates were employed as cat’s eye output couplers in order to suppress power degradation due to optical damage. From the results of a long-term frequency-stabilization test, mode-hop-free operation for about one week was demonstrated. After a continuous operation of about three weeks, the power degradation was less than 10%. The results show the potential of such interference-filter-stabilized ECDLs for practical and portable quantum technologies such as atomic clocks or atomic interferometers.
Bayesian vs Evolutionary Optimisation in Exploring Pareto Fronts for Materials Discovery
Authors: Low Kai Yuan Andre , Vissol-Gaudin Eleonore , Lim Yee Fun , Hippalgaonkar Kedar 
Published: September 2022

<p> With advancements in automated experimental setups, material optimisation and discovery can scale to higher throughput with larger evaluation budgets. Two state-of-the-art algorithms with conceptually different multi-objective optimisation strategies (Bayesian and Evolutionary) are compared on synthetic and real-world datasets. Our results show that the Bayesian optimisation strategy, q-Noisy Expected Hypervolume Improvement (qNEHVI) is superior in finding solutions at the Pareto Front rapidly, and when considering hypervolume improvement as a performance indicator. On the other hand, the Evolutionary optimisation strategy, Unified Non-dominated Sorting Genetic Algorithm III (U-NSGA-III), can exploit the Pareto Front and propose a larger pool of optimal solutions, given sufficient evaluation budget, and thus may be a better choice for materials discovery problems where knowing the complete Pareto Front provides greater scientific value to understanding materials space. We discuss the limitations of using hypervolume as a performance indicator for optimisation strategies, alongside hypervolume-based strategies such as qNEHVI, which do not adequately explain the number of solutions at or near the Pareto Front. We also performed a comparison of both optimisation strategies at different batch sizes to consider throughput capabilities. </p>
Application of data analysis and game theory to competitive Pokémon battle sets
Authors: Bhagwat Dhruva 
Published: September 2022

<p>This paper analyzes a scenario where two hypothetical Pokémon trainers each have 3 Pokémon and each send out 1 to battle. We form an experiment through repeated battles between each Pokémon matchup to create payoff values for each Pokémon. Game theory and the process of finding a Nash equilibrium are applied to this scenario to determine both the best outcome for both trainers, and how the results state which trainer has more powerful Pokémon sets. Iterated dominance, best responses, and mixed strategies are used routinely to solve for the Nash equilibrium solution. The application of game theory, Nash equilibrium, and data analysis to economics is briefly discussed. </p>
Multiplex PCR screening for virulence genes of Klebsiella pneumoniae isolated from microbiota of diseased and healthy people
Authors: Pay G. V. , Rakitina D. V. , Sukhina M. A. , Yudin S. M. , Makarov V. V. , Maniya T. R. , Zagaynova A. V. 
Published: September 2022

Introduction. Klebsiella pneumoniae in human microbiota may appear as a part of commensal microbiota, and as hypervirulent pathogen, for example, hypermucoid pathotype. This pathotype is characterized by certain genetic determinants, leading to the possibility of detecting the pathogenic potential of isolates by PCR. Aim of the study: to evaluate and compare pathogenic potential of K. pneumoniae isolates from practically healthy people, patients with inflammatory bowel disease (IBD) and extraintestinal infections (ExII).Materials and methods. Testing was performed with the set of nucleotides for multiplex PCR analysis targeting eight potentially virulent genes with the following functions: ferrum uptake (ybsT, kfu, iutA), adhesion and invasion (mrkD), hypermucoid phenotype and virulent serotypes (mrkD, magA, rmpA, k2) and metabolism of allantoin (allS). PCR assay was used to screen Klebsiella pneumoniae isolates from feces of patients with IBD (69 isolates) and of practically healthy people (68 isolates), and multiresistant isolates from biological material (blood, urine, surgical wounds, bronchoalveolar lavage) of patients with extraintestinal infections (mrExII, 25 isolates).Results. Results of the testing demonstrated association of four of targeted determinants with the patients diagnoses. YbtS gene was significantly more often found in isolates from IBD (р = 0.024) and mrExII (p 0.001) groups. RmpA gene was significantly more often detected in IBD group (р = 0.038). Extraintestinal infectious isolates were significantly (р ≤ 0.001) enriched with mrkD and allS genes (р = 0.032).Conclusion. The most potentially virulent group was isolated from patients with extraintestinal infections, the least virulent — isolates from feces of practically healthy people. The most frequently detected virulence genes were involved in adhesion and hypermucoid phenotype formation.