bluuebunny/crossref_metadata_2025_split huggingface dataset:
A dynamic handover scheme based on bidirectional VLC channel in multi-user attocell networks
Authors: Wang Liqiang , Han Dahai , Zhang Min , Wu Jingtao , Jiang Xiaotian , He Jingsuo 
Published: July 2022

AbstractLight fidelity (LiFi) would be a potential optical wireless communications technology for future mixed-spectrum 5G/6G indoor attocell network, which uses light-emitting diodes based as an optical antenna and offers Gbits capacity. For this scenario, a dynamic handover scheme based on bidirectional visible light communications (VLC) channel is proposed, which uses the uplink light sources to characterize terminal’s movement status for the mobility and make the handover decision in contrast to the unidirectional links. The uplink reference signal received power and the movement state are examined, and the created algorithm is executed in the bidirectional VLC test bed. The experimental results show that the proposed method will reduce the terminal’s handover rate by up to 45% and increase the optical network throughput by up to 26% at the experimental data rate compared with the skipping handover scheme for indoor LiFi network.
Evaluating measurement properties of subjective cognitive decline self-reported outcome measures: a systematic review
Authors: Ibnidris Aliaa , Robinson Janelle N. , Stubbs Marissa , Piumatti Giovanni , Govia Ishtar , Albanese Emiliano 
Published: July 2022

Abstract
Background
Subjective cognitive decline (SCD) is present in the early stage of preclinical Alzheimer’s disease (AD) and is associated with an increased risk of further cognitive decline and AD dementia later in life. Early detection of at-risk groups with subjective complaints is critical for targeted dementia prevention at the earliest. Accurate assessment of SCD is crucial. However, current measures lack important psychometric evaluations and or reporting.

Objectives
To systematically evaluate measurement properties of self-reported outcome measures (PROMs) used to assess SCD in the older adult population with or at risk of AD.

Methods and analysis
We used the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols 2015 Checklist for reporting. We conducted a literature search, screened, and included validation studies of SCD based on self-reported questionnaires from both population-based and clinical studies, conducted in older adults (≥ 55). We critically appraised the included primary studies using the Consensus-based Standards for the selection of health Measurement Instruments (COSMIN) guidelines.

Results
Sixteen studies met the inclusion criteria. The included studies reported psychometric properties of 17 SCD self-reported questionnaires. We extracted data on the structural validity, internal consistency, test-retest reliability, and cross-cultural validity and found a widespread proneness to bias across studies, and a marked heterogeneity is assessed and reported measurement properties that prevented the consolidation of results.

Conclusion
Our findings suggest that available SCD questionnaires lack content validity evaluation. Currently available measurements of SCD lack development and validation standards. Further work is needed to develop and validate SCD self-reported measurement with good quality measurement properties.
Dynamics analysis and optimal control of SIVR epidemic model with incomplete immunity
Authors: Liu Yiming , Jian Shuang , Gao Jianguo 
Published: July 2022

AbstractIn this paper, we establish an SIVR model with diffusion, spatially heterogeneous, latent infection, and incomplete immunity in the Neumann boundary condition. Firstly, the threshold dynamic behavior of the model is proved by using the operator semigroup method, the well-posedness of the solution and the basic reproduction number $\Re _{0}$

ℜ
0

are given. When $\Re _{0}<1$

ℜ
0

<
1
, the disease-free equilibrium is globally asymptotically stable, the disease will be extinct; when $\Re _{0}>1$

ℜ
0

>
1
, the epidemic equilibrium is globally asymptotically stable, the disease will persist with probability one. Then, we introduce the patient’s treatment into the system as the control parameter, and the optimal control of the system is discussed by applying the Hamiltonian function and the adjoint equation. Finally, the theoretical results are verified by numerical simulation.
Patients’ experiences of continued treatment with extended-release naltrexone: a Norwegian qualitative study
Authors: Marciuch Anne , Brenna Ida Halvorsen , Weimand Bente , Solli Kristin Klemmetsby , Tanum Lars , Røstad Bente K. , Birkeland Bente 
Published: July 2022

Abstract
Background
The opioid antagonist extended-release naltrexone (XR-NTX) in the treatment of opioid use disorder (OUD) is effective in terms of safety, abstinence from opioid use and retention in treatment. However, it is unclear how patients experience and adjust to losing the possibility of achieving an opioid effect. This qualitative study is the first to explore how people with opioid dependence experience XR-NTX treatment, focusing on the process of treatment over time.

Methods
Using a purposive sampling strategy, semi-structured interviews were undertaken with 19 persons with opioid use disorder (15 men, four women, 22–55 years of age) participating in a clinical trial of XR-NTX in Norway. The interviewees had received at least three XR-NTX injections. Qualitative content analysis with an inductive approach was used.

Findings
Participants described that XR-NTX treatment had many advantages. However they still faced multiple challenges, some of which they were not prepared for. Having to find a new foothold and adapt to no longer gaining an effect from opioids due to the antagonist medication was challenging. This was especially true for those struggling emotionally and transitioning into the harmful use of non-opioid substances. Additional support was considered crucial. Even so, the treatment led to an opportunity to participate in society and reclaim identity. Participants had strong goals for the future and described that XR-NTX enabled a more meaningful life. Expectations of a better life could however turn into broken hopes. Although participants were largely optimistic about the future, thinking about the end of treatment could cause apprehension.

Conclusions
XR-NTX treatment offers freedom from opioids and can facilitate the recovery process for people with OUD. However, our findings also highlight several challenges associated with XR-NTX treatment, emphasizing the importance of monitoring emotional difficulties and increase of non-opioid substances during treatment. As opioid abstinence in itself does not necessarily equal recovery, our findings underscore the importance of seeing XR-NTX as part of a comprehensive, individualized treatment approach.
Trial registration: Clinicaltrials.gov # NCT03647774, first Registered: Aug 28, 2018.
Intraoperative mild hyperoxia may be associated with improved survival after off-pump coronary artery bypass grafting: a retrospective observational study
Authors: Ju Jae-Woo , Choe Hyun Woo , Bae Jinyoung , Lee Seohee , Cho Youn Joung , Nam Karam , Jeon Yunseok 
Published: July 2022

Abstract
Background
The effect of hyperoxia due to supplemental oxygen administration on postoperative outcomes in patients undergoing cardiac surgery remains unclear. This retrospective study aimed to evaluate the relationship between intraoperative oxygen tension and mortality after off-pump coronary artery bypass grafting (OPCAB).

Methods
The study included adult patients who underwent isolated OPCAB between July 2010 and June 2020. Patients were categorised into three groups based on their intraoperative time-weighted average arterial oxygen partial pressure (PaO2): normoxia/near-normoxia (< 150 mmHg), mild hyperoxia (150–250 mmHg), and severe hyperoxia (> 250 mmHg). The risk of in-hospital mortality was compared using weighted logistic regression analysis. Restricted cubic spline analysis was performed to analyse intraoperative PaO2 as a continuous variable. The risk of cumulative all-cause mortality was compared using Cox regression analysis.

Results
The normoxia/near-normoxia, mild hyperoxia, and severe hyperoxia groups included 229, 991, and 173 patients (n = 1393), respectively. The mild hyperoxia group had a significantly lower risk of in-hospital mortality than the normoxia/near-normoxia (odds ratio [OR], 0.12; 95% confidence interval [CI], 0.06–0.22) and severe hyperoxia groups (OR, 0.06; 95% CI, 0.03–0.14). Intraoperative PaO2 exhibited a U-shaped relationship with in-hospital mortality in the non-hypoxic range. The risk of cumulative all-cause mortality was significantly lower in the mild hyperoxia group (hazard ratio, 0.72; 95% CI, 0.52–0.99) than in the normoxia/near-normoxia group.

Conclusions
Maintaining intraoperative PaO2 at 150–250 mmHg was associated with a lower risk of mortality after OPCAB than PaO2 at < 150 mmHg and at > 250 mmHg. Future randomised trials are required to confirm if mildly increasing arterial oxygen tension during OPCAB to 150–250 mmHg improves postoperative outcomes.
Clinical characteristics, socioeconomic factors and COVID-19 were associated with delayed surgery in children with hypospadias: a retrospective study of 4439 cases in a single center
Authors: Bai Gaochen , Liang Feng , Zhao Tianxin , Deng Fuming , Fu Kai , Chen Xiong , Li Zhongmin , Zhang Liyu , Jia Wei , Fu Wen , Liu Guochang 
Published: July 2022

Abstract
Background
Hypospadias is one of the most common congenital diseases of the genitourinary system in children. The European Association of Urology (EAU) Guidelines recommend that children undergoing hypospadias surgery should be between 6 and 18 months. In China, where many children have hypospadias, it remains unknown whether clinical characteristics, socioeconomic factors and COVID-19 were associated with delayed surgery in children with hypospadias.

Methods
We retrospectively analyzed children with hypospadias who underwent primary surgery at the Department of Pediatric Urology in Guangzhou Women and Children’s Medical Center between January 2010 and October 2021. Patients who had two-stage surgery or a second round of surgery due to complications were excluded to eliminate data duplication. The clinical characteristics and demographic information were collected. We defined delayed surgery as primary surgery performed after 18 months following the EAU Guidelines.

Results
A total of 4439 children diagnosed with hypospadias were included in the study. The median age (29.1 ± 16.7 months) of surgery for hypospadias in our study was much higher than the recommended age reported in the EAU guidelines, and 76.6% of the children underwent surgery after the age of 18 months. Children without comorbidities including cryptorchidism (odds ratio [OR] = 1.562; 95% confidence interval [CI] 1.199–2.034; p = 0.001), prostatic cyst (OR = 2.613; 95% CI 1.579–4.324; p < 0.001), penile hypoplasia (OR = 1.778; 95% CI 1.225–2.580; p = 0.002), inguinal hernia (OR = 2.070; 95% CI 1.394–3.075; p < 0.001), and penoscrotal transposition (OR = 4.125; 95% CI 1.250–13.619; p = 0.020) were more likely to receive delayed surgery. Living in a low economic area (OR = 1.731; 95% CI 1.068–2.806; p = 0.026) or not close to a main medical center (OR = 1.580; 95% CI 1.370–1.824; p < 0.001) was highly associated with delayed surgery. The proportion of children undergoing delayed surgery and the median age of surgery during the COVID-19 pandemic were significantly higher than those before the COVID-19 pandemic (p = 0.004 and < 0.001, respectively).

Conclusions
Most children with hypospadias received delayed surgery (surgical age > 18 months). Comorbidities, living in a low economic area, too far from a main medical center and the COVID-19 pandemic were highly associated with delayed surgery. It is vital to improve the public awareness of hypospadias and strengthen the re-education of primary community doctors to reduce delayed surgery.
Use of 3D models as a didactic resource in archaeology. A case study analysis
Authors: Arias Francisco , Enríquez Carlos , Jurado Juan Manuel , Ortega Lidia , Romero-Manchado Antonio , Cubillas Juan José 
Published: July 2022

Abstract
The generation of 3D models through Terrestrial Laser Scanning has proved to be valuable tools for the study, documentation and recreation of archaeological remains. In this context, it is described how to generate a physical model to provide not only to researchers, but also as teaching material for teachers for university students, facilitating their access and study. As a practical case, this article describes the acquisition, processing and management of archaeological data in the archaeological site of Cástulo, Jaén, in South Spain. We expound how to get the 3D-printed model of the Muslim tower, showing how it is possible to generate a scale and very reliable reproduction of the structure, being also an useful and tangible material in the teaching of cultural heritage.
Multidisciplinary approach to Gorlin-Goltz syndrome: from diagnosis to surgical treatment of jawbones
Authors: Spadari Francesco , Pulicari Federica , Pellegrini Matteo , Scribante Andrea , Garagiola Umberto 
Published: July 2022

AbstractBackgroundGorlin syndrome, also known as Gorlin-Goltz syndrome (GGS) or basal cell nevus syndrome (BCNS) or nevoid basal cell carcinoma syndrome (NBCCS), is an autosomal dominant familial cancer syndrome. It is characterized by the presence of numerous basal cell carcinomas (BCCs), along with skeletal, ophthalmic, and neurological abnormalities. It is essential to anticipate the diagnosis by identifying the pathology through the available diagnostic tests, clinical signs, and radiological manifestations, setting up an adequate treatment plan.Main bodyIn the first part, we searched recent databases including MEDLINE (PubMed), Embase, and the Cochrane Library by analyzing the etiopathogenesis of the disease, identifying the genetic alterations underlying them. Subsequently, we defined what are, to date, the major and minor clinical diagnostic criteria, the possible genetic tests to be performed, and the pathologies with which to perform differential diagnosis. The radiological investigations were reviewed based on the most recent literature, and in the second part, we performed a review regarding the existing jawbone protocols, treating simple enucleation, enucleation with bone curettage in association or not with topical use of cytotoxic chemicals, and “en bloc” resection followed by possible bone reconstruction, marsupialization, decompression, and cryotherapy.ConclusionTo promote the most efficient and accurate management of GGS, this article summarizes the clinical features of the disease, pathogenesis, diagnostic criteria, differential diagnosis, and surgical protocols. To arrive at an early diagnosis of the syndrome, it would be advisable to perform radiographic and clinical examinations from the young age of the patient. The management of the patient with GGS requires a multidisciplinary approach ensuring an adequate quality of life and effective treatment of symptoms.
Probiotic viability, pH and lactic acid concentration of opened commercial probiotic dairy drinks stored at different temperatures and durations
Authors: Liew Yun Khoon , Aung Kyan , Chan Li Li , Baskaran Sandhya , Mak Siew Thong 
Published: July 2022

Abstract
Background
The commercial cultured milk drinks contain either single or mixed probiotic species and supply in different serving sizes. It is known that different combinations of probiotics might provide the various products’ quality in terms of nutritional value during their manufacturing process. However, a lack of information about probiotic viability and physicochemical properties of the opened fermented products for continuous fermentation leads to the driving force in conducting this study. Therefore, four locally available cultured milk drinks (branded Y, F, N and V) with 20 bottles each were aseptically transferred into their respective sterile containers and stored at 4 °C, 25 °C and − 20 °C for 1–13 days. Then, the viable cells were quantified using the drop plate method on de Man, Rogosa and Sharpe (MRS) agar. The pH change was investigated using the calibrated pH meter, and the Enzytec D-/L-Lactic acid kit determined the content of D-lactic acid via spectrophotometer. Eventually, the data were analysed using the statistical tool.

Results
The viability of probiotics in brands Y and V was significantly increased even when stored at − 20 °C and 4 °C with at least 1 log CFU/mL increment. The proliferation of probiotics was moderately influenced by the pH of the opened cultured milk. High content of D-lactate was found in Y- and F-branded products after 13 days of storage. The Y-branded cultured milk drink had the highest content of D-lactate with 0.52 g/L and 0.40 g/L when stored for 13 days at room temperature and 4 °C, respectively.

Conclusions
This study sheds light on the necessity to elucidate the properties of opened probiotic beverages over time, especially when bottled in large quantities. This allows some improvement steps.
Does the degree of intraoperatively identified cartilage loss affect the outcomes of primary total knee arthroplasty without patella resurfacing? A prospective comparative cohort study
Authors: Shon Oog-Jin , Kim Gi Beom 
Published: July 2022

Abstract
Purpose
The aim of this study was to investigate whether the degree of patellar cartilage loss confirmed during index surgery affects the clinical and radiologic outcomes of total knee arthroplasty (TKA) performed without patellar resurfacing.

Methods
We prospectively divided 2012 patients with a minimum follow-up of 12
months into two groups according to intraoperatively graded cartilage lesions graded using
the International Cartilage Repair Society (ICRS) system: group 1, grades 0‒2 (n = 110); group 2, grades
3‒4 (n = 102). Relevant locations, such as medial, lateral, or both facets of the patella, were also assessed. Clinical outcomes were assessed using the Western Ontario and McMaster Universities Osteoarthritis Index, Feller’s patella score, and Kujala anterior knee pain score. Radiographic outcomes included patellar tilt angle and lateral patellar shift on Merchant’s view.

Results
Clinical and radiographic outcomes were not significantly different between the two groups. No patient underwent secondary patellar resurfacing. Although the lateral facet was significantly more involved, there were no significant differences in outcomes.

Conclusions
The degree of intraoperatively identified patellar cartilage loss did not affect the short-term outcomes following primary TKA without patellar resurfacing.
Level of evidence II: Prospective comparative study.
Factors affecting range of motion following two-stage revision arthroplasty for chronic periprosthetic knee infection
Authors: Kim Doo-Yeol , Seo Young-Chae , Kim Chang-Wan , Lee Chang-Rack , Jung Soo-Hwan 
Published: July 2022

Abstract
Introduction
The purpose of this study was to evaluate factors that affect range of motion (ROM) following two-stage revision arthroplasty as a treatment for chronic periprosthetic knee infection.

Materials and methods
A total of 98 patients diagnosed with chronic periprosthetic joint infection (PJI) following primary total knee arthroplasty between January 2009 and December 2019 and then underwent two-stage revision arthroplasty were reviewed retrospectively. Multiple regression analysis was performed to evaluate the factors that affect ROM after two-stage revision arthroplasty. ROM after two-stage revision arthroplasty was used as a dependent variable, while age at the time of surgery, ROM at PJI diagnosis, ROM after the first-stage surgery, the interval between the first-stage surgery and the second-stage surgery, whether a re-operation was performed before the second-stage surgery, culture results (culture negative or culture positive), and body mass index (BMI) were used as independent variables.

Results
Multiple regression analysis (R2 = 0.843) revealed that among the independent variables, ROM (β = 0.604, P < 0.001) after the first-stage surgery, whether a re-operation was performed before the second-stage surgery (β =  − 8.847, P < 0.001), the interval between the first-stage surgery and the second-stage surgery (β = − 0.778, P = 0.003), and BMI (β =  − 0.698, P = 0.041) were associated with ROM after two-stage revision arthroplasty, the dependent variable.

Conclusions
In two-stage revision arthroplasty for chronic periprosthetic knee infection, ROM after the first-stage surgery, whether a re-operation was performed before the second-stage surgery, the interval between the first-stage surgery and the second-stage surgery, and BMI were found to be factors that were associated with ROM after two-stage revision arthroplasty.
Developing criteria for research translation decision-making in community settings: a systematic review and thematic analysis informed by the Knowledge to Action Framework and community input
Authors: Wende Marilyn E. , Wilcox Sara , Rhodes Zoe , Kinnard Deborah , Turner-McGrievy Gabrielle , McKeever Brooke W. , Kaczynski Andrew T. 
Published: July 2022

Abstract
Background
There is a pressing need to translate empirically supported interventions, products, and policies into practice to prevent and control prevalent chronic diseases. According to the Knowledge to Action (K2A) Framework, only those interventions deemed “ready” for translation are likely to be disseminated, adopted, implemented, and ultimately institutionalized. Yet, this pivotal step has not received adequate study. The purpose of this paper was to create a list of criteria that can be used by researchers, in collaboration with community partners, to help evaluate intervention readiness for translation into community and/or organizational settings.

Methods
The identification and selection of criteria involved reviewing the K2A Framework questions from the “decision to translate” stage, conducting a systematic review to identify characteristics important for research translation in community settings, using thematic analysis to select unique research translation decision criteria, and incorporating researcher and community advisory board feedback.

Results
The review identified 46 published articles that described potential criteria to decide if an intervention appears ready for translation into community settings. In total, 17 unique research translation decision criteria were identified. Of the 8 themes from the K2A Framework that were used to inform the thematic analysis, all 8 were included in the final criteria list after research supported their importance for research translation decision-making. Overall, the criteria identified through our review highlighted the importance of an intervention’s public health, cultural, and community relevance. Not only are intervention characteristics (e.g., evidence base, comparative effectiveness, acceptability, adaptability, sustainability, cost) necessary to consider when contemplating introducing an intervention to the “real world,” it is also important to consider characteristics of the target setting and/or population (e.g., presence of supporting structure, support or buy-in, changing sociopolitical landscape).

Conclusions
Our research translation decision criteria provide a holistic list for identifying important barriers and facilitators for research translation that should be considered before introducing an empirically supported intervention into community settings. These criteria can be used for research translation decision-making on the individual and organizational level to ensure resources are not wasted on interventions that cannot be effectively translated in community settings to yield desired outcomes.