bluuebunny/crossref_metadata_2025_split huggingface dataset:
Torsion of the spermatic cord in adults: a multicenter experience in adults with surgical exploration for acute scrotal pain with suspected testicular torsion
Authors: Dang Van Thi , Pradere Benjamin , Varennes Anne Mauger de , Benali Nadia Ali , Vallée Maxime , Berchiche William , Gondran-Tellier Bastien , Margue Gaelle , Michiels Clément , Gaillard Charles , Grevez Tristan , Bardet Florian , Hulin Maud , Manuguerra Anthony , Pinar Ugo , Plassais Caroline , Felber Margeux , Wandoren William , Kaulanjan Kévin , Dominique Ines , Sbizerra Marc , Mazancourt Emilien Seizilles de , Matillon Xavier , Duquesne Igor , Chabenes Maxime , Gaillard Victor , Freton Lucas , Lannes Francois , Khene Zine-Eddine 
Published: March 2022

ABSTRACT
Acute scrotal pain (ASP) requiring surgical exploration is common in the pediatric population, but little has been reported on this subject with regard to the adult population. The aim of this study was to investigate the demographic and clinical characteristics and outcomes of scrotal explorations performed on adult patients. Patients over 21 years of age who underwent surgical exploration for ASP with suspected testicular torsion (TT) at 14 French hospitals between January 2005 and December 2019 were included in this study. The main outcome measures were demographic characteristics, pathology found during scrotal exploration, and perioperative outcomes. Logistic regression was used to perform univariate and multivariate analyses to identify predictors of TT. Data for 1329 men were analyzed. The median age was 30 (interquartile range [IQR]: 25–35; range: 21–89) years. Regarding the clinical examination, 867 (65.2%) patients presented with an elevation of the testicle, 613 (46.1%) patients with scrotal edema or erythema, and 211 (15.9%) patients with nausea or vomiting. Operative findings identified TT in only 684 (51.5%) patients, epididymo-orchitis in 112 (8.4%) patients, a tumor in 16 (1.2%) patients, and no causes in 475 (35.7%) patients. Orchiectomy for nonviable testes was required in 101 (7.6%) patients. In multivariate analysis, an elevation of the testicle, erythema/swelling, and the presence of nausea/vomiting were found to be associated with the occurrence of TT. Testicular torsion is not exclusive to children and adolescents, so must be considered in males of any age with acute scrotal findings. However, one-third of scrotal explorations in adults did not lead to a diagnosis.
Comparative Evaluation of Autogenous Bone Graft and Autologous Platelet-Rich Fibrin with and Without 1.2 mg in situ Rosuvastatin Gel in the Surgical Treatment of Intrabony Defect in Chronic Periodontitis Patients
Authors: Gautam Kompal , Kapoor Anjali , Mathur Setu , Ali A. Rizwan , Choudhary Aparna , Shekhawat Arpana 
Published: March 2022

Context:
Rosuvastatin (RSV) is a new synthetic, hydrophilic statin with potent anti-inflammatory and osseodifferentiation actions. Autogenous bone graft (ABG) is still considered the gold standard in reconstructive bone surgery. Addition of platelet-rich fibrin (PRF) to ABG provides sustained release of various growth factors and facilitates survival of the graft.

Aims:
The study aims to clinically and radiographically compare the effectiveness of ABG and PRF with and without 1.2 mg RSV gel in the surgical treatment of intrabony defect in chronic Periodontitis patient.

Settings and Design:
This was a randomized controlled clinical trial.

Subjects and Methods:
Thirty-nine patients (one site per participant) with chronic periodontitis were randomly divided into three groups: Group 1 (open flap debridement [OFD] + placebo), Group 2 (OFD + ABG + PRF), and Group 3 (OFD + ABG + PRF + 1.2 mg RSV). Relative attachment level (RAL) and probing pocket depth (PPD) were recorded at baseline, 3, 6, and 9 months. Radiographic measurements such as defect height (A and B) and defect width (C) were calculated at baseline and 9 months.

Statistical Analysis Used:
Intergroup comparison was done using Kruskal–Wallis ANOVA. An intragroup comparison was done using Friedman test and Wilcoxon signed-rank test.

Results:
The mean PPD reduction and mean RAL gain were highly significant in Group 3 and Group 2 than Group 1. For Group 3, a significant reduction of defect height and width and a significant amount of bone fill were achieved than Group 2 and Group 1.

Conclusions:
Addition of 1.2 mg RSV gel, PRF, and ABG has synergistic effects, explaining their role as a regenerative material in the treatment of intrabony defects.
COVID-19 vaccination status in Indian patients with cancer
Authors: Batra Ullas , Nathany Shrinidhi , Bansal Nitin , Sharma Mansi 
Published: March 2022

Background:
Patients with cancer are at an increased risk of severe coronavirus disease-2019 (COVID-19). Hence, safe and efficacious vaccination against COVID-19 may play a crucial role in conferring protection to this group of patients.

Objectives:
As there are no dedicated trials testing the safety and efficacy of COVID-19 vaccines in immunocompromised individuals or patients with cancer, we conducted this study to assess the vaccination status of Indian patients with cancer.

Materials and Methods:
This single-center observational study was conducted in the Department of Medical Oncology at the Rajiv Gandhi Cancer Institute and Research Centre, Delhi, India, between March and June 2021. Patients with cancer were interviewed telephonically to obtain information related to their vaccination status. The primary endpoint was the proportion of patients with cancer who received a COVID-19 vaccine. The Chi-squared test and McNemar's test were used to determine the associations between the different variables and the vaccination status.

Results:
Of the 752 patients included in the study, 219 (29.1%) had received at least one dose of the COVID-19 vaccine. Of these, 34 (15.5%) patients subsequently developed COVID-19. They were treated in domiciliary care and did not require hospitalization. Of the 533 patients (70.9%) who were not vaccinated, 117 (21.9%) tested positive for COVID-19 and 14 (11.9%) succumbed to the disease.

Conclusion:
Our study suggests that there is probably a lack of awareness or fear related to vaccination, which should be addressed to avoid COVID-19-related cancer mortality.
Knowledge, perception, and attitude of the general population toward cancer and cancer care
Authors: Padmanabhan Maya , Balasubramanian Satheesan , Muhammed Sha E. K. , Malodan Riyas 
Published: March 2022

Background:Despite the advances in the field of oncology, the diagnosis of cancer is often considered a death sentence, owing to the misconceptions and myths about cancer treatment. Moreover, improvements in health literacy and awareness about cancer have also not been able to change the attitude of people toward cancer-related health behaviors.Objective:In this study, we aimed to evaluate the knowledge, perception, and attitude of the general population toward cancer and cancer care.Materials and Methods:This cross-sectional study was conducted at Malabar Cancer Center, a tertiary cancer center in Kerala, India, between June 2017 and February 2018. A survey was conducted in the general population in the northern part of Kerala in the districts of Kannur, Kasargod, and Wayanad during a medical camp. People who were aged above 18 years and could read the Malayalam language were included in the study. The participants were administered a questionnaire comprising 26 questions, and the knowledge, perception, and attitude of the general population toward cancer and cancer care were evaluated.Results:A total of 487 people responded to the survey. Of these, 354 (72.7%) were women and 133 (27.3%) were men. The mean age of the cohort was 43.7 years. About 74% of the participants disagreed that all cancers can be treated using the same treatment modalities. A total of 84% of the participants agreed that cancer can be detected early with screening. Almost 95% of the participants were aware of the importance of cancer screening and strongly recommended establishing cancer screening clinics in government setups.Conclusion:There is a positive attitude among the general public toward cancer. Almost all the people surveyed were interested in attending cancer awareness programs, believed in the role of screening and felt that establishing cancer screening programs would be useful. This may help provide a road map for cancer policy-makers.
Brief Technical Guide for Registration of an Observational Study Protocol
Authors: Mondal Himel , Mondal Shaikat , Mahapatra Amita Kumar 
Published: March 2022

Background:
Clinical trial registration is a must for the conduct of an interventional study. The registration should be in the repositories accepted by World Health Organization (WHO) and endorsed by the International Committee of Medical Journal Editors (ICMJE). These registries allow the registration of both interventional and observational studies. However, the majority of the observational studies are not registered.

Aims:
We aimed to find the current share of observational studies in various registries and to provide a brief technical guide on the process of registration of an observational study in the Clinical Trials Registry – India (CTRI) and in the open science framework (OSF).

Methods:
We searched the WHO and ICMJE websites for the list of accepted registries. The number of interventional and observational studies in those registries was collected. Then, we described the process of registration of an observational study in CTRI and OSF.

Results:
The highest number (83,866) of observational studies is present in ClinicalTrials.gov. However, according to percentage, the DRKS - German Clinical Trials Register has the highest percentage (31.57%) of observational studies. The CTRI has 25.33% and ClinicalTrials.gov has 21.91% observational studies. The registration of an observational study protocol is acceptable online and free of cost in the CTRI and OSF.

Conclusion:
It is not mandatory to register purely observational studies. However, the registration may bring transparency in scientific reporting and help to avoid publication bias towards positive results. The technical glimpse in this article would help the novice authors in registering their observational study protocol in an open repository.
Observational study of new-onset atrial fibrillation in patients treated with Ivabradine alone versus Ivabradine and β-blocker drug (The BetaBrad Study)
Authors: Thanedar Rohan S. , Kudva Srinivas , Sanzgiri Prakash , Reddy Charan 
Published: March 2022

Introduction:
Ivabradine is a heart rate lowering agent by inhibiting Iƒ current in sinus node. It is approved for use in patients with angina and heart failure for heart rate control. Recently, the concern has grown over increased incidence of atrial fibrillation in patients treated with Ivabradine.

Aims:
We observed critically ill patients in the intensive care unit, treated with Ivabradine alone versus Ivabradine plus a β-blocking agent, and compared the incidence of new-onset atrial fibrillation.

Settings and Design:
This was an observational, single-center study.

Materials and Methods:
We observed 40 patients who were divided into two groups. One group of patients was treated with Ivabradine (no other heart rate-controlling agent) and the other group was treated with Ivabradine plus a β-blocker drug. We studied the incidence of atrial fibrillation in an observation period of 7 days in the intensive care unit along with other patient characteristics. We used appropriate analytical protocol to compare the two groups.

Statistical Analysis Used:
Student’s unpaired t test and Fisher’s exact probability test were applied. The value of P < 0.05 was considered statistically significant.

Results:
Although one patient treated with Ivabradine (and no other rate/rhythm controlling drug) had new-onset atrial fibrillation, there was no statistically significant increase in the incidence of atrial fibrillation in critically ill patients (during the observation period) treated with Ivabradine versus Ivabradine plus β-blocker drug.

Conclusion:
Our preliminary research suggests the use of Ivabradine for heart rate control in critically ill patients is not associated with an increased incidence of new-onset atrial fibrillation. However, we recommend a further larger study on this subject.
To assess the risk of obstructive sleep apnea in type 2 diabetes mellitus patients in a tertiary care center in Eastern India
Authors: Dash Satarupa , Thakur Atanu 
Published: March 2022

Background:
Obstructive sleep apnea (OSA) and type 2 diabetes mellitus have a major health impact because of their high prevalence worldwide. Obesity is a common risk factor for both OSA and type 2 diabetes mellitus in middle-aged persons.

Aim:
This study was conducted to assess the risk of OSA in type 2 diabetes mellitus patients.

Materials and Methods:
A cross-sectional study was performed at the tertiary care center of Veer Surendra Sai Institute of Medical Sciences and Research, Burla, Odisha, India. Type 2 diabetic patients were evaluated to assess the risk of OSA using the STOP-BANG sleep apnea questionnaire (consisting of eight questions).

Results:
Of the 150 type 2 diabetic patients, 53.8% had low risk, 28.6% had intermediate risk, and 17.6% had a severe risk for OSA based on questionnaires. Patients with comorbid conditions like hypertension (odds ratio 1.5) and obesity (odds ratio 1.06) have a high risk of OSA. There was a significant relationship between the type of medication and the risk of developing OSA (P < 0.05) in diabetic patients. The patients taking both insulin and oral drugs have a high-risk OSA as compared to those taking only insulin or only oral drugs.

Conclusion:
The prevalence of OSA is much higher in diabetics than in the general population, the risk is increasing with comorbid conditions like obesity and hypertension, patients who are receiving both oral hypoglycemic drugs and insulin. The screening of OSA among diabetic patients is necessary to identify those at high risk and manage this problem, which may remain undiagnosed in many patients.
Changing trends of patients undergoing thrombolysis for acute ST-elevated myocardial infarction in tertiary care hospital in Maharashtra, India
Authors: Kadam Shilpa Deshmukh 
Published: March 2022

Background:
Coronary artery disease (CAD) is becoming a major cause of morbidity and mortality burden in the developing world. Indians have been associated with a more severe form of CAD that has its onset at a younger age group with a male predominance. Reperfusion of the occluded coronary artery at the earliest is the most important aim of management of acute ST-elevation myocardial infarction (STEMI).

Aim:
The aims of this work were to (1) study the changing trends in patients presenting with STEMI, (2) the outcomes of patients undergoing thrombolysis in a tertiary care hospital, and (3) the increasing trend of CAD in young (CADY).

Materials and Methods:
A total of 500 patients undergoing thrombolysis between January 2017 and December 2019 were studied retrospectively. We studied the age of presentation, sex, agents used for thrombolysis, their angiography findings, and their management and outcome.

Results:
CADY in less than 45 years of age was noted in 26.2% in our study. It was more common in men. Left anterior descending coronary artery (LAD) was the most common artery to be involved in single-vessel coronary artery disease (SVCAD) patients followed by the right coronary artery (RCA). Door to needle time in our study was 28 min.

Conclusion:
The prevalence of CADY Indians in our study was significantly high. The most common age group of men presenting with STEMI was 51–55 years, followed by 45–50 years. The most common age group of women presenting with CAD was 61–65 years.
Diurnal activity patterns, habitat use and foraging habits of Egyptian goose (Alopochena egyptiacus Linnaeus, 1766) in the Boyo wetland, southern Ethiopia
Authors: Kassa Mulugeta , Balakrishnan M. , Afework Bezawork 
Published: March 2022

Egyptian goose (Alopochena egyptiacus) is a resident bird species in Africa South of the Sahara occurring throughout the entire Nile Valley. Despite the wide distribution, the available information on its behavioral ecology is limited in Ethiopia. A study on the activity patterns, habitat use and foraging habits of Egyptian goose was carried out in and around Boyo wetland, Ethiopia, during the dry and wet seasons. Scan sampling method was used to study the activity patterns and habitat use of Egyptian goose in grassland, mudflat and shallow water habitats of the wetland. The feeding behavior of Egyptian goose was also observed in the surrounding farmland habitats using scan sampling method. Generally, Egyptian geese spent most of their time resting (39.81%) followed by foraging (32.64%). They spent 10.43% of their time in comfort movement preening or stretching. The rest of their time was allocated for locomotion (6.63%), vigilance (5.75%), and social behavior (1.59%), and other activities (2.86%). Most of the birds were engaged in foraging activity in the morning (07:00-9:00 h) and afternoon (16:00 - 18:00 h) hours both during the wet and dry seasons. About 39% of Egyptian geese were scanned in mudflat, 31.5% in grassland, and 30.05% in shallow water habitats engaged in different activities. Most individuals used the grassland habitat for foraging during the dry (59.5%) and wet (74%) seasons, while they used shallow water and mudflat habitats for resting both during the wet and dry seasons seasons. The birds were observed foraging mainly grass during the dry (93.62%) and wet (59.52%) seasons. The Egyptian geese show diurnal activity pattern with feeding peaks in early morning and late afternoon hours as is observed in many other avian taxa. The Boyo wetland is also as an important foraging ground for this species and other birds in the area. Further ecological studies on the species and impact of human activities on the Boyo wetland should be conducted for the conservation of the avifauna.
MALEZAS EN EL CULTIVO DE PIÑA CV. MD-2 Y SU CONTROL CON HERBICIDAS Y ACOLCHADO DE Spathodea campanulata
Authors: Vargas-Laró Nelson , Robles Wilfredo , Lugo-Torres María de L. , Morales-Payán José Pablo 
Published: March 2022

MALEZAS EN EL CULTIVO DE PIÑA CV. MD-2 Y SU CONTROL CON HERBICIDAS Y ACOLCHADO DE Spathodea campanulata
To the history of nykhas
Authors: Туаллагов А.А. 
Published: March 2022

По заключению исследователей, «нартовские ныхасы» и аналогичные имкомплексы являются памятниками аланского периода. В прошлом они служили святи-лищами, посвященными женскому божеству и одновременно связанными с судебной дея-тельностью. Связь суда с культом Богини-матери соотносится с некоторыми осетин-скими фольклорно-этнографическими материалами, позволяющими полагать наличиеоригинальной древнеирано-скифо-алано-осетинской параллели. Образ богини был изна-чально связан с представлениями о миропорядке и законе. В рамках ее культа и моглопроисходить становление и функционирование судов.
According to the conclusion of the researchers, the «nykhases of the Narts» andsimilar complexes are monuments of the Alanian period. In the past, they served as sanctuariesdedicated to a female deity and at the same time associated with judicial activities. The connectionbetween the court and the cult of the Mother Goddess is correlated with some Ossetian folkloreand ethnographic materials, which suggest the existence of an original ancient Iranian-Scythian-Alano-Ossetian parallel. The image of the goddess was originally associated with ideas about theworld order and the law. Within the framework of her cult, the formation and functioning of courtscould take place.
CONTRIBUTION TO THE DEVELOPMENT OF AGRICULTURAL SCIENCE OF THE FREE ECONOMIC SOCIETY AT THE BELARUSIAN STATE
POLYTECHNICAL INSTITUTE (1921–1922)
Authors: Dubovik Aliaksandr K. 
Published: March 2022

The article considers the activities of a scientific society acting in
1921–1922 under the name of the Belarusian Free Economic Society in the Belarusian State Polytechnical Institute (BSPI) and created on the basis the Belarusian State Institute of Agriculture. The significance of the agronomic (agricultural) section of
society in the development of agricultural science is shown. The article marks the important role played by the chairman of the society, the first rector of the BSPI, a research agronomist Nikanor Yaroshevich, as well as by the chairman of the agricultural section Sergei Skandrakov and other agricultural scientists.
MATERIALIZATION OF THE ACHIEVEMENTS OF AGRICULTURAL SCIENCE IN SOVIET BELARUS INTO PRODUCTION: DIRECTIONS AND MECHANISMS (1955-1985)
Authors: Smekhovich Nikalay V. 
Published: March 2022

From 1955 to 1985, the development of agriculture in Soviet Belarus depended to a great extent on the solution of the problem of materialization of the achievements of agricultural science into production. The essence of the problem stemmed from the need to provide strong connection between agrarian research institutes (hereinafter referred to as the RI) and state farm production. During the studied period the evolution of directions and mechanisms of materialization of agrarian science achievements in production was observed. In 1955, a directive
mechanism was created, the main element of which was the bureaucratic apparatus of the state agricultural management system. However, the officials did not pay much attention to the implementation of scientific achievements in production, and this
mechanism did not work properly. To solve the problem, the all-union and republican leadership attempted to create an economic mechanism in 1963, but this idea did not succeed. As a result, in 1965 the forced economic mechanism was modernized and
began to function, the main element of which were RI, agricultural science personnel.
AT THE ORIGINS OF AGRICULTURAL EDUCATION: THE HISTORY OF THE BELARUSIAN STATE AGRICULTURAL ACADEMY
Authors: Medvedeva Galina E. 
Published: March 2022

The article traces the history of the Belarusian State Agricultural
Academy in Gorki from its foundation in 1840 to the present day. The stages of its formation and development, achievements and influence on agriculture of tsarist Russia have been described. The contribution of the Academy to the agricultural and higher education of the country has been considered. The article gives special attention to the scientists who are widely known both in our country and abroad as well, to those who have left a significant mark in science thanks to their scientific and pedagogical activities.
The Heroic Chamber – an Outlook on the Right Ventricle in Eisenmenger Syndrome
Authors: Hernic Alecsandra , Enache Roxana , Radu Daniela-Noela , Coman Ioan M. , Ginghină Carmen 
Published: March 2022

Abstract
Despite being at the extreme spectrum of congenital heart disease-associated pulmonary hypertension, patients with Eisenmenger syndrome have better outcomes compared to other types of pulmonary arterial hypertension, especially in the case of post-tricuspid shunts. This survival advantage seems to be at least partly due to significant resilience of the right ventricle and a relative resistance to failure. This paper aims to review the concept of right ventricular adaptive remodeling in Eisenmenger syndrome, its impact on prognosis and the role of multimodality imaging in the right ventricle's assessment in this setting.