bluuebunny/crossref_metadata_2025_split huggingface dataset:
Proto-constructivism in Novosibirsk architecture in 1917-1927
Authors: Mzhelskii V. M. 
Published: June 2022

Purpose: The analysis of the architecture of the first post-revolutionary decade, processes and origins of the new style constructivism. The paper highlights the architecture of this period. Design/methodology/approach: Interesting factual material on proto-constructivism and its main problems. Comparison of different viewpoints on the processes in Novosibirsk architecture and the analysis based on the data collected. Research findings: This style is preceded by rather an interesting stage of creative research, which needs a special study. At that time, a significant number of public and administrative buildings were built in Novosibirsk, which was associated with its transformation to the administrative center of the Siberian Krai. It was an important period in the history of the Soviet architecture, when a search for a new creative method, architectural principles was carried out in the capital and regions, although researchers paid less attention to it than to constructivism. Architecture of post-revolutionary decade is characterized by a multi-vector nature and a pronounced desire for rationalism and functionalism, while still retaining the styles of the previous era associated with the struggle of various directions; new stylistic search for the post-revolutionary period. Practical implications: The obtained results contribute to the study of origins of the Soviet avantgarde architecture and can be used in further research and training manuals in the field. Originality/value: The analysis of the different viewpoints on the reasons for the Soviet avant-garde architecture development; comparison with the facts; identification of differences between the viewpoints, which is important for further study of this topic.
Edge effect of the tank wall-bottom joint on service reliability of vertical steel tank
Authors: Khizhnyakov V. I. , Negodin A. V. , Bakshanskiy R. Yu. 
Published: June 2022

The paper presents the analysis of the edge effect in the wall bending of a vertical steel tank RVS-20000 using a comparison between the results obtained by using the bending theory and membrane theory. It is shown that the condition of the wall-bottom joint strength is satisfied in both cases.The stresses obtained according to the bending theory with regard to multiplying safety factor, exceed the maximum stresses by 11.1 % obtained by using the membrane theory with account for the edge effect. This makes it possible to use the membrane theory equations in calculating the wall thickness, which excludes complex calculations of the bending theory. Unlike the membrane theory, the membrane theory provides the stress and strain calculation of the T-junction. The results obtained indicate that the service reliability of the wall-bottom joint is primarily determined by the preparation quality of the tank base, welding quality of the T-junction (including negative temperatures) and the methods of their flaw detection on the construction site.
Primer Plan operativo para la vigilancia genómica sistemática y rutinaria nacional del SARS-COV-2 en Ecuador
Authors: De Mora Doménica , Olmedo Vela Maritza Guadalupe , Paez Michelle , Garcés Jimmy , González González Manuel , Logroño Denis , Bruno Alfredo 
Published: June 2022

El 30 de enero de 2020 la Organización Mundial de la Salud (OMS) declaró emergencia de salud pública de importancia internacional, debido al incremento vertiginoso de personas afectadas por un nuevo coronavirus denominado SARS CoV-2. El 11 de marzo de 2020, tras su diseminación global, se estableció como pandemia. Posteriormente se reportó a nivel internacional la aparición de nuevas variantes que implican escenarios epidemiológicos complejos para los que se requiere mantener sistemas de vigilancia genómica operativos, activos y robustos que permitan monitorizar la evolución de la pandemia a nivel mundial y de la epidemia en cada país
La vigilancia mundial de las secuencias genéticas del SARS-CoV-2 sirve de apoyo a la respuesta ante la pandemia de COVID-19. Además facilita el seguimiento de la propagación geográfica y temporal del SARS-CoV-2, la pronta detección y evaluación de mutaciones que puedan influir en la capacidad patogénica, la transmisión del virus o en las medidas de respuesta adoptadas (medidas no farmacológicas, vacunas, el tratamiento y las pruebas diagnósticas)
ISLAMIC SCHOLARS’ NETWORK IN SOUTH SULAWESI AT THE 20th CENTURY: A Note in Wajo and Soppeng
Authors: Al-Rasyid Hamzah Harun , Ilyas Husnul Fahima 
Published: June 2022

This article discussed about the network of scholars in South Sulawesi concentrated in Wajo and Soppeng districts. This research was significant to reconstruct and introduce scholars at the local level who were almost publicized, even though they had dedicated themselves in creating, educating, and attacking the nation's children with adequate religious knowledge. The primary concerns of this study were: how was the formation of the Islamic scholars <em>(Ulama)</em>’s network in South Sulawesi, and what were the roles of the Ulama in the formation of the network? This study aimed at reconstructing the network of Ulama over the achipleago, South Sulawesi, and Middle Eastern during the twentieth century. The results of this study revealed that the Ulama’s network in South Sulawesi, especially Wajo and Soppeng, highly relied on the Haramain network. Haramain alumni had a major influence on the development of traditional Islamic education in the form of <em>halaqah</em><em> (traditional teaching)</em>. For example, the halaqah center was formed in the early twentieth century at Salemo, Ajjakang/Mangkoso, Cabalu, and Wajo. Especially in Wajo KH. Muhibuddin or populary known as Ambo Emme, the initiator who encouraged KH. As'ad from Mecca to visit Sengkang Wajo in 1928, to teach about the Islamic values through halaqah developed by Ambo Emme. Halaqah had been changed into MAI (now the Islamic Boarding School of Asadiyah) which had produced a number of known scholars in building the halaqah and pesantren networks in the South Sulawesi region. They are, for example, KH. Daud Ismail from Soppeng who formed the YASRIB Islamic University Soppeng, KH. Yunus Martan in MAI-Wajo, KH. Abdurrahman Ambo Dalle from Wajo at MAI Mangkoso (now DDI), KH. Abduh Pabbaja from Sidenreng Rappang in DDI Ujung Lare and PP Al-Furqan, KH. Abdul Kadir Khalid MA from Wajo established MDIA Bontoala, KH. Asyri in developing the Darul Arqam Gombara Islamic Boarding School and Darul Aman.
SANTRI'S PERCEPTION TOWARDS KITAB KUNING LEARNING METHODS AT AS'ADIYAH SENGKANG ISLAMIC BOARDING SCHOOL
Authors: Sultan Muslihin , Awaluddin A. Fajar , Subair Muh. 
Published: June 2022

<p>Research on the method of <em>kitab kuning</em> learning has been widely carried out by many scholars, yet there is still a lack of research examining how to read the kitab kuning with the mumtaz method quickly. To complement the existing research, this study investigates the perception of As'adiyah Sengkang Islamic boarding school students towards <em>Mumtaz</em> learning methods. Using a perception case study research design, the study reported three things. First<em>, Mumtaz's</em> learning included ten chapters of material that began with recognizing word and keyword identity, vocabulary, verb change and ended with a change in the final line of words in the form of <em>kitab kuning</em> reading practices. Second, the application of the <em>Mumtaz</em> method consists of four stages, and third, the perception of students towards the <em>Mumtaz</em> learning method is positive and negative. Positive perception occurs because <em>Mumtaz's</em> material is easy to understand, and the learning method is quite fun because it always uses rhythmic songs. On the other hand, negative perceptions occur not because of the material problems and learning methods but because of a short duration of time and not directly applied to the <em>kitab kuning</em>, but partial book-based examples. This research implies that this learning method is worth applying and disseminating in various Islamic universities in Indonesia.</p><p> </p>
DIRECTING A DRAMA-COMEDY FILM ENTITLED “HANI”
Authors: Saleh Mahammad , Rahmad Cito Yasuki 
Published: June 2022

Early marriage remains a social problem, especially among less-educated urban people, including in Tamanan District, Bondowoso Regency, East Java Province. The community has a distinctive and unique Pandalungan language that offers an interesting idea source for filmmaking. Thus, this creation seeks to illustrate how “Hani”, a drama-comedy film, was directed with a local-culture approach. The production of “Hani” referred to the existing Standard Operating Procedures (SOP) in the audiovisual profession and combined the visual comedy and slapstick approaches. The direction of “Hani” indicates that using local culture (Pandalungan language) in each storyline and local actor character can create an entertaining and educating comedy film. Further, the film produced is an audiovisual work that is easily understandable by the local community.
“BEAUTY OF MEN” DANCE CHOREOGRAPHY
Authors: Trisnawan Arrofan Ryan , Rokhim Nur 
Published: June 2022

The evolution of high heels from women’s to men’s and finally to jockeys’ footwear in horse racing has attracted the authors. The wearers’ poses and movements can be elevated to a level of dance. Likewise, the drag queen in the Cabaret show faces difficulties in his personal and professional life. The choreographic form of “Beauty of Men” entails the creation of this dance. The dance work of “Beauty of Men” is presented in ensembles. This dance work is composed and presented by developing dance movements. The dance work consists of four sections, beginning with introducing the self’s inner conflict. The first section designates the issues that confront families and communities. The second section describes the difficulties associated with social friendship. The third section illustrates the self’s difficulties and the quest for self-identity. Lastly, the fourth section expresses how the problems encountered were resolved. The process of creating the dance work of “Beauty of Men” reflects the dancer’s creative ability as a result of his experience.
Temperature-Driven Developmental Modulation of Yield Response to Nitrogen in Wheat and Maize
Authors: Sadras Victor O. , Giordano Nicolas , Correndo Adrian , Cossani C. Mariano , Ferreyra Juan M. , Caviglia Octavio P. , Coulter Jeffrey A. , Ciampitti Ignacio A. , Lollato Romulo P. 
Published: June 2022

Nitrogen management is central to the economic and environmental dimensions of agricultural sustainability. Yield response to nitrogen fertilisation results from multiple interacting factors. Theoretical frameworks are lagging for the interaction between nitrogen and air temperature, the focus of this study. We analyse the relation between yield response to nitrogen fertiliser and air temperature in the critical period of yield formation for spring wheat in Australia, winter wheat in the US, and maize in both the US and Argentina. Our framework assumes (i) yield response to nitrogen fertiliser is primarily related to grain number per m2, (ii) grain number is a function of three traits: the duration of the critical period, growth rate during the critical period, and reproductive allocation, and (iii) all three traits vary non-linearly with temperature. We show that “high” nitrogen supply may be positive, neutral, or negative for yield under “high” temperature, depending on the part of the response curve captured experimentally. The relationship between yield response to nitrogen and mean temperature in the critical period was strong in wheat and weak in maize. Negative associations for both spring wheat in Australia and winter wheat with low initial soil nitrogen (&lt; 20 kg N ha-1) in the US highlight the dominant influence of a shorter critical period with higher temperature; with high initial soil nitrogen (&gt; 120 kg N ha-1) that favoured grain number and compromised grain fill, the relation between yield response to nitrogen and temperature was positive for winter wheat. The framework is particularly insightful where data did not match predictions; a non-linear function integrating development, carbon assimilation and reproductive partitioning bounded the pooled data for maize in the US and Argentina, where water regime, previous crop, and soil nitrogen overrode the effect of temperature on yield response to nitrogen fertilisation.
Synthesis and Evaluation of Coumarin-Chalcone Derivatives as α-Glucosidase Inhibitors
Authors: Hu Chun-Mei , Luo Yong-Xin , Wang Wen-Jing , Li Jian-Ping , Li Meng-Yue , Zhang Yu-Fei , Xiao Di , Lu Li , Xiong Zhuang , Feng Na , Li Chen 
Published: June 2022

Coumarin and chalcone, two important kinds of natural product skeletons, both exhibit α-glucosidase inhibitory activity. In this work, coumarin-chalcone derivatives 3 (a∼v) were synthesized, and their α-glucosidase inhibitory activity was screened. The results showed that all synthetic derivatives (IC50: 24.09 ± 2.36 to 125.26 ± 1.18 μM) presented better α-glucosidase inhibitory activity than the parent compounds 3-acetylcoumarin (IC50: 1.5 × 105 μM) and the positive control acarbose (IC50: 259.90 ± 1.06 μM). Among them, compound 3t displayed the highest α-glucosidase inhibitory activity (IC50: 24.09 ± 2.36 μM), which was approximately 10 times stronger than that of acarbose. The kinetic assay of 3t (KI = 18.82 μM, KIS = 59.99 μM) revealed that these compounds inhibited α-glucosidase in a mixed-type manner. Molecular docking was used to simulate the interaction between α-glucosidase and compound 3t.
Genetic Characterization of Chikungunya Virus Among Febrile Dengue Fever–Like Patients in Xishuangbanna, Southwestern Part of China
Authors: Zou Meng , Su Chunyan , Li Tingting , Zhang Jing , Li Daiying , Luan Ning , Ma Dehong , Liu Jiansheng , Sun Qiangming , Peng Xiaozhong , Liu Hongqi 
Published: June 2022

Co-infection of chikungunya virus (CHIKV) has been recently reported during dengue fever epidemics. However, the infection of CHIKV is often neglected due to its misdiagnosis as dengue virus (DENV) infection. In the summer of 2019 when dengue fever was epidemic, we collected 697 serum samples from febrile dengue fever–like patients in Xishuangbanna, southwestern part of China. DENV RNA was detectable in 99.42% of these patients. Notably, 88 patients (12.62%) showed the presence of CHIKV RNA, among which 86 patients were co-infected with DENV and CHIKV. We sequenced and analyzed the full genome of CHIKV virus in four out of 88 samples (two CHIKV infected and two co-infected). The results suggested that the four strains were all Asian genotype and had the highest homology (99.4%) with the SZ1239 strain (accession number MG664851) isolated in 2012 and possibly introduced from Indonesia. Further comparison with the conserved sequences in the whole genome of 47 strains of CHIKV showed that there were 13 and 15 amino acid mutants in structural proteins and non-structural proteins, respectively. The previously reported adaptive mutations of E2-W64R, E2-I211T, E2-K233E, E1-A98T, and E1-K211E occurred in the four strains of this study. In conclusion, this study reports a co-infection of CHIKV during the DENV epidemic in the city Xishuangbanna, 2019. Molecular epidemiology revealed that CHIKV identified in this study was indigenous and belongs to Asian lineage with lineage-specific mutations and some reported adaptive mutations, which is distinct from the recently reported CHIKV (East/Central/South African) in Ruili, the city next to Xishuangbanna.
The Disconnect Between Development and Intended Use of Clinical Prediction Models for Covid-19: A Systematic Review and Real-World Data Illustration
Authors: Prosepe Ilaria , Groenwold Rolf H. H. , Knevel Rachel , Pajouheshnia Romin , van Geloven Nan 
Published: June 2022

BackgroundThe SARS-CoV-2 pandemic has boosted the appearance of clinical predictions models in medical literature. Many of these models aim to provide guidance for decision making on treatment initiation. Special consideration on how to account for post-baseline treatments is needed when developing such models. We examined how post-baseline treatment was handled in published Covid-19 clinical prediction models and we illustrated how much estimated risks may differ according to how treatment is handled.MethodsFirstly, we reviewed 33 Covid-19 prognostic models published in literature in the period up to 5 May 2020. We extracted: (1) the reported intended use of the model; (2) how treatment was incorporated during model development and (3) whether the chosen analysis strategy was in agreement with the intended use. Secondly, we used nationwide Dutch data on hospitalized patients who tested positive for SARS-CoV-2 in 2020 to illustrate how estimated mortality risks will differ when using four different analysis strategies to model ICU treatment.ResultsOf the 33 papers, 21 (64%) had misalignment between intended use and analysis strategy, 7 (21%) were unclear about the estimated risk and only 5 (15%) had clear alignment between intended use and analysis strategy. We showed with real data how different approaches to post-baseline treatment yield different estimated mortality risks, ranging between 33 and 46% for a 75 year-old patient with two medical conditions.ConclusionsMisalignment between intended use and analysis strategy is common in reported Covid-19 clinical prediction models. This can lead to considerable under or overestimation of intended risks.
Neural Dysconnectivity in the Hippocampus Correlates With White Matter Lesions and Cognitive Measures in Patients With Coronary Artery Disease
Authors: Niu Jianhua , Zhang Jingchen , Yan Jueyue , Xu Zhipeng , Fang Xing , You Jingyu , Liu Zhihai , Wu Weifang , Li Tong 
Published: June 2022

PurposeRecent neuroimaging reports have shown the microstructural changes in coronary artery disease (CAD) and its correlation with cognitive dysfunction while little is known about the functional characteristics of CAD. We hypothesize that functional characteristics may give clues to underlying pathology in CAD and its link with cognitive dysfunction. Degree centrality (DC), a graph-based assessment of network organization was performed to explore the neural connectivity changes in CAD patients compared with healthy controls and their correlation with cognitive measures.MethodsThirty CAD patients and 36 healthy controls were included in our study. All participants underwent functional magnetic resonance imaging (fMRI) of the brain. We performed DC analysis to identify voxels that showed changes in whole-brain functional connectivity with other voxels. DC was measured by the fMRI graph method and comparisons between the two groups were done. All participants underwent neuropsychological assessment (Montreal Cognitive Assessment, MoCA and Mini-Mental State Examination, MMSE).ResultsOur data analysis included 30 CAD patients (59.90 ± 7.53 years) and 36 HCs (61.61 ± 6.19 years). CAD patients showed a greater prevalence of white matter lesions using the Fazekas score than healthy controls (P &lt; 0.001). Importantly, CAD patients showed significantly lower (P &lt; 0.001) MoCA and MMSE scores compared with healthy controls. CAD patients showed significantly decreased DC value (P &lt; 0.001) in the right hippocampus (hippocampus_R), right lingual gyrus (lingual_R), and significantly increased DC value (P &lt; 0.001) in the left middle frontal gyrus (Frontal_Mid_L) when compared with healthy controls respectively. DC value in the hippocampus_R significantly correlated (P &lt; 0.00) with MMSE and MoCA scores in CAD patients. Fazekas scores in CAD patients showed a significant correlation (P &lt; 0.001) with the DC value in the hippocampus_R.ConclusionThese findings suggest that reduced cerebral neural connectivity in CAD may contribute to their cognitive impairment and white matter microstructural damage.
Duplex Ultrasonography for the Evaluation of Extracranial Vertebral Artery: A Prospective Comparison With Digital Subtraction Angiography
Authors: Zhang Jie , Xing Yingqi , Cui Li 
Published: June 2022

Background and ObjectivePatients with symptomatic vertebral artery stenosis are at high risk of stroke recurrence, especially ≥70% stenosis. Revascularization may be considered for extracranial vertebral artery stenosis in patients with recurrent ischemic events despite optimal medical management. Currently, there is a lack of consensus on the ultrasonic evaluation of extracranial vertebral artery stenosis in clinical practice. This study aimed to validate the efficiency of duplex ultrasonography and assess the optimal sonographic thresholds for predicting extracranial vertebral artery stenosis.MethodsThis is a prospective study of all patients with symptomatic posterior circulation stroke/transient ischemic attack who were scheduled to undergo digital subtraction angiography from April 2020 to October 2021. A total of 544 vertebral arteries with a normal lumen or extracranial stenosis confirmed with digital subtraction angiography were included in the study. The peak systolic velocity at the V1 segment (PSVv1) and the V2 segment (PSVv2) were measured and the PSVv1/PSVv2 and PSVv2/PSVv1 ratios were calculated. The cutoff values were determined using receiver operating characteristic analysis.ResultsThe areas under the receiver operating characteristic curve of all the velocity parameters to predict extracranial vertebral artery stenosis were &gt;0.80. The cutoff values for predicting ≥50% and ≥70% V1 segment stenosis were PSVv1 ≥146 cm/s (sensitivity 76.2%, specificity 86.3%) and PSVv1/PSVv2 ratio ≥2.2 (sensitivity 84.3%, specificity 77.6%), and PSVv1 ≥184 cm/s (sensitivity 80.8%, specificity 87.1%) and PSVv1/PSVv2 ratio ≥3.5 (sensitivity 79.5%, specificity 90.5%), respectively. The cutoff values for predicting ≥50% and ≥70% V2 segment stenosis were PSVv2 ≥80 cm/s (sensitivity 75.0%, specificity 91.0%) and PSVv2/PSVv1 ratio ≥1.2 (sensitivity 75.0%, specificity 94.8%), and PSVv2 ≥111 cm/s (sensitivity 81.0%, specificity 95.0%) and PSVv2/PSVv1 ratio ≥1.7 (sensitivity 81.0%, specificity 96.6%), respectively.ConclusionSymptomatic patients with the ultrasonic parameters of PSVv1 ≥146 cm/s and PSVv1/PSVv2 ratio ≥2.2 at V1 segment or PSVv2 ≥80 cm/s and PSVv2/PSVv1 ratio ≥1.2 at V2 segment need to be considered for further verification by digital subtraction angiography to seek revascularization. If the parameters increase to PSVv1 ≥184 cm/s and PSVv1/PSVv2 ratio ≥3.5 at the V1 segment or PSVv2 ≥111 cm/s and PSVv2/PSVv1 ratio ≥1.7 at the V2 segment, these patients have an increased risk of recurrent stroke and are more likely to need revascularization. The results can be used as a reference for the assessment and long-term management of patients with extracranial VA stenosis.