bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mycophenolate Mofetil Induced-Colitis: Is it More about Clinical Diagnosis?
Authors: Nagandran Yoghini , Mandal Saikat , Zahar Ayuni Zahirah 
Published: January 2025

Background:
Mycophenolate mofetil (MMF) is an immunosuppressant commonly
used for treating autoimmune diseases.

Case Presentation:
We report a diagnostically challenging case of MMF-induced colitis in a patient
after 3 years of initiation of MMF therapy. A 76-year-old Caucasian female with a history of
Chronic inflammatory demyelinating polyneuropathy receiving MMF presented to the hospital
with a 7-weeks history of watery diarrhoea and crampy abdominal pains. Routine blood investigations,
CMV-PCR, stool culture, viral PCR, Colonoscopy, and CT scan of the abdomen were broadly
within normal limits. Histopathological changes were not significantly diagnostic apart from
ischaemic-type changes. Finally, the reduction of the MMF dose caused the cessation of diarrhoea.
Diagnosing MMF-induced colitis can be challenging, especially in patients on immunosuppressive
medications. Further, long latency periods and non-specific colonoscopic and histopathologic
changes add to the diagnostic dilemma.

Conclusion:
MMF-induced diarrhoea should be part of the clinician’s differentials, and the decision
to reduce the dose of MMF needs to be considered once infection and other causes have been
ruled out.
Nutritional Deficiency Anemia Status among Adolescent Girls in North Lombok District, West Nusa Tenggara, Indonesia
Authors: Mulianingsih Misroh , Suriah Suriah , Hidayanty Healthy , Amiruddin Ridwan , Hadju Veny , Salmah Andi Ummu , Yusron Meyka Aris 
Published: January 2025

Introduction
Anemia is a major health problem affecting adolescents worldwide. This problem should receive proper attention due to its significant adverse health, social, and economic impacts. This study aims to collect comprehensive data and factors associated with anemia status in adolescent girls.

Methods
This study used a quantitative approach with a cross-sectional study method. The population was all girls aged 15-19 in the working area of Bayan and Gangga Health Centers, North Lombok, Indonesia. The sample size was 400. Anemia status was determined by hemoglobin examination, incidence of Chronic Energy Deficiency (CED) status, and nutritional status by mid-upper arm circumference (MUAC) measurement and body mass index-for-age Z-score measurement.

Results
A total of 76% of adolescents were anemic. Tests showed a strong link between anemia and: hematocrit level, CED, and nutritional status in adolescent girls (p < 0.05). The tests showed a strong link between CED status and anemia in adolescent girls (p < 0.05).

Conclusion
Adolescent girls who experience iron deficiency anemia are more likely to be found in those who experience CED. Adolescent girls must pay more attention to adequate and varied food intake to improve nutritional status and prevent iron deficiency anemia.
A Narrative Review on Aggression in Children and Adolescents:
Anthropology, Developmental Phenomenology, Transdiagnostic
Trajectories, Contextual Nosology, and Strategic Pathways for
Interventions
Authors: Gupta Mayank , Gupta Nihit 
Published: January 2025

Introduction/Objective::
The transdiagnostic construct of aggression in
children and adolescents is often characterized by distinct mental phenomena,
such as irritability, emotional dysregulation (ED), anger, and outbursts. However,
these terms are frequently interchanged in clinical settings despite their distinct
semantic nuances. Therefore, it is critical to delve into the complex dynamics of
aggression, irritability, and emotional dysregulation in the child and adolescent
population.

Methods::
An extensive search was conducted across diverse databases using the
keywords "Aggression," "Violence," "Irritability," and "Emotional
dysregulation." This search encompassed articles on childhood aggression,
covering its prevalence, risk factors, clinical manifestations, assessment methods,
treatment modalities, and prognostic indicators. Initial screening identified 261
articles, with 40 selected for the initial draft and an additional 15 included later,
either manually or via reverse citations.

Results::
The appraisal of aggression is challenging due to its terminology and
diagnostic complexities, especially in distinguishing normative behavior from
psychopathological impairments. There is a significant lack of empirical
evidence, like systematic reviews concerning the heterogenous dimensional
understanding of aggression, including its social determinants, comorbidities, and
targeted interventions. Likewise, there is a crucial need to assess comorbid
conditions like ADHD, DMDD, and ODD to gain deeper insights into their
developmental, social, and biological determinants. Emphasizing comorbidity
assessment and age of onset during initial diagnostic evaluations is vital, followed
by a structured approach to interventions encompassing behavioral and
pharmacological strategies.

Conclusion::
There is a need for a stepwise multidimensional assessment towards
contextual understanding of aggression and sequencing the treatment of
aggression in children and adolescents. It is paramount to incorporate tailored
interventions with shared decision-making.
Team Chemistry and COVID in European Football
Authors: de Graaf Jip 
Published: January 2025

Objective:
This research investigates the influence of team chemistry and COVID on football matches.

Methods:
This is done by estimating the effect of both chemistryand COVID on match results and analysing the performance of prediction models where both effects are included and threshold intervals are usedfor classification. Four different chemistry measures are introduced and all are evaluated.

Results:
Chemistry has the expected positive effect on performance only for the top teams in the estimations where interaction effects are included for two different chemistry measures. COVID has the expected mitigating effect on home advantage.
The inclusion of both effects in prediction models does not increase prediction accuracy consistently, although for various symmetric threshold intervals the prediction models with chemistry and COVID included outperforming the baseline models.

Conclusion:
Chemistry can have a positive influence on the perfomrance of a team and empty stadiums due to COVID mitigate the effect of home advantage. Including COVID and chemistry measures based on region in predictions is highly recommended.
Non-verbal Communication of Sports Leaders and Influence on Students' Participation Satisfaction, Positive Emotion, Exercise Adherence, and Sport Recommendation
Authors: Chung Ji-Young , Jeong Seung-Hoon 
Published: January 2025

Background and Study Aim:
This study analyzed the relationship between the nonverbal communication of golf leaders' and the satisfaction, positive emotion, exercise adherence, and recommendation of sports leaders among students participating in golf classes.

Material and Methods:
The study surveyed 377 students in four middle and four high schools in Seoul and Gyeonggi Province from January 2 to May 2, 2020. The SPSS 23.0 and AMOS 23.0 programs were used to conduct these procedures: reliability analyses to analyze the validity and reliability of the survey questions; confirmatory factor analysis; the correlation between nonverbal communication and various variables; and a structural equation model (SEM) analysis to empirically verify the hypotheses of the study.

Results:
Results showed that five major hypotheses and five of the 18 sub-hypotheses had significant effects among the independent and dependent variables. The golf leaders’ paralanguage and physical appearance significantly affected the participation satisfaction of youth participants. In addition, their physical appearance had a statistically significant effect on the exercise adherence of the youth participants. In turn, the participation satisfaction among the youth participants significantly affected their positive emotions, exercise adherence, and recommendation of golf leaders. In effect, their positive emotion significantly affected their recommendations of golf leaders to others.

Conclusion:
Hence, sports leaders should learn nonverbal communication skills through continuous self-management, class preparation, and active demonstrations among their students.
Effectiveness of Outpatient Chronic Pain Management for Middle-Aged Patients by Internet Hospitals: Retrospective Cohort Study
Authors: Sang Ling , Zheng Bixin , Zeng Xianzheng , Liu Huizhen , Jiang Qing , Liu Maotong , Zhu Chenyu , Wang Maoying , Yi Zengwei , Song Keyu , Song Li 
Published: January 2025

Abstract

Background
Chronic pain is widespread and carries a heavy disease burden, and there is a lack of effective outpatient pain management. As an emerging internet medical platform in China, internet hospitals have been successfully applied for the management of chronic diseases. There are also a certain number of patients with chronic pain that use internet hospitals for pain management. However, no studies have investigated the effectiveness of pain management via internet hospitals.

Objective
The aim of this retrospective cohort study was to explore the effectiveness of chronic pain management by internet hospitals and their advantages and disadvantages compared to traditional physical hospital visits.

Methods
This was a retrospective cohort study. Demographic information such as the patient’s sex, age, and number of visits was obtained from the IT center. During the first and last patient visits, information on outcome variables such as the Brief Pain Inventory (BPI), medical satisfaction, medical costs, and adverse drug events was obtained through a telephone follow-up. All patients with chronic pain who had 3 or more visits (internet or offline) between September 2021, and February 2023, were included. The patients were divided into an internet hospital group and a physical hospital group, according to whether they had web-based or in-person consultations, respectively. To control for confounding variables, propensity score matching was used to match the two groups. Matching variables included age, sex, diagnosis, and number of clinic visits.

Results
A total of 122 people in the internet hospital group and 739 people in the physical hospital group met the inclusion criteria. After propensity score matching, 77 patients in each of the two groups were included in the analysis. There was not a significant difference in the quality of life (QOL; QOL assessment was part of the BPI scale) between the internet hospital group and the physical hospital group (P=.80), but the QOL of both groups of patients improved after pain management (internet hospital group: P<.001; physical hospital group: P=.001). There were no significant differences in the pain relief rate (P=.25) or the incidence of adverse events (P=.60) between the two groups. The total cost (P<.001) and treatment-related cost (P<.001) of the physical hospital group were higher than those of the internet hospital group. In addition, the degree of satisfaction in the internet hospital group was greater than that in the physical hospital group (P=.01).

Conclusions
Internet hospitals are an effective way of managing chronic pain. They can improve patients’ QOL and satisfaction, reduce treatment costs, and can be used as part of a multimodal strategy for chronic pain self-management.
Validation of Sleep Measurements of an Actigraphy Watch: Instrument Validation Study
Authors: Waki Mari , Nakada Ryohei , Waki Kayo , Ban Yuki , Suzuki Ryo , Yamauchi Toshimasa , Nangaku Masaomi , Ohe Kazuhiko 
Published: January 2025

Background
The iAide2 (Tokai) physical activity monitoring system includes diverse measurements and wireless features useful to researchers. The iAide2’s sleep measurement capabilities have not been compared to validated sleep measurement standards in any published work.

Objective
We aimed to assess the iAide2’s sleep duration and total sleep time (TST) measurement performance and perform calibration if needed.

Methods
We performed free-living sleep monitoring in 6 convenience-sampled participants without known sleep disorders recruited from within the Waki DTx Laboratory at the Graduate School of Medicine, University of Tokyo. To assess free-living sleep, we validated the iAide2 against a second actigraph that was previously validated against polysomnography, the MotionWatch 8 (MW8; CamNtech Ltd). The participants wore both devices on the nondominant arm, with the MW8 closest to the hand, all day except when bathing. The MW8 and iAide2 assessments both used the MW8 EVENT-marker button to record bedtime and risetime. For the MW8, MotionWare Software (version 1.4.20; CamNtech Ltd) provided TST, and we calculated sleep duration from the sleep onset and sleep offset provided by the software. We used a similar process with the iAide2, using iAide2 software (version 7.0). We analyzed 64 nights and evaluated the agreement between the iAide2 and the MW8 for sleep duration and TST based on intraclass correlation coefficients (ICCs).

Results
The absolute ICCs (2-way mixed effects, absolute agreement, single measurement) for sleep duration (0.69, 95% CI –0.07 to 0.91) and TST (0.56, 95% CI –0.07 to 0.82) were moderate. The consistency ICC (2-way mixed effects, consistency, single measurement) was excellent for sleep duration (0.91, 95% CI 0.86-0.95) and moderate for TST (0.78, 95% CI 0.67-0.86). We determined a simple calibration approach. After calibration, the ICCs improved to 0.96 (95% CI 0.94-0.98) for sleep duration and 0.82 (95% CI 0.71-0.88) for TST. The results were not sensitive to the specific participants included, with an ICC range of 0.96-0.97 for sleep duration and 0.79-0.87 for TST when applying our calibration equation to data removing one participant at a time and 0.96-0.97 for sleep duration and 0.79-0.86 for TST when recalibrating while removing one participant at a time.

Conclusions
The measurement errors of the uncalibrated iAide2 for both sleep duration and TST seem too large for them to be useful as absolute measurements, though they could be useful as relative measurements. The measurement errors after calibration are low, and the calibration approach is general and robust, validating the use of iAide2’s sleep measurement functions alongside its other features in physical activity research.
Efficacy and Acceptability of a Mobile App for Monitoring the Clinical Status of Patients With Chronic Obstructive Pulmonary Disease Receiving Home Oxygen Therapy: Randomized Controlled Trial
Authors: Naranjo-Rojas Anisbed , Perula-de Torres Luis Ángel , Cruz-Mosquera Freiser Eccehomo , Molina-Recio Guillermo 
Published: January 2025

Background
Chronic obstructive pulmonary disease (COPD) primarily originates from exposure to tobacco smoke, although factors, such as air pollution and exposure to chemicals, also play a role. One of the primary treatments for COPD is oxygen therapy, which helps manage dyspnea and improve survival rates. Mobile health (mHealth) technologies have demonstrated significant potential in monitoring patients with chronic diseases, offering new avenues for enhancing patient care and disease management.

Objective
The purpose of this study was to evaluate the efficacy and acceptability of a mobile app designed for the clinical monitoring of patients with COPD and home oxygen (HO) therapy, compared with conventional monitoring in real-world community settings.

Methods
A parallel-group, nonblinded, multicenter randomized controlled trial was conducted with 45 participants; the intervention group (IG), which used the mobile app in addition to conventional monitoring (n=23) and the control group, which received only conventional monitoring (n=22), administered by therapists over a duration of 3 months. The primary outcomes included the chronic obstructive pulmonary disease assessment test (CAT) score, the level of dyspnea measured by the Borg scale, and oxygen saturation percentage, assessed at both the beginning and end of the trial. Secondary outcomes included the frequency of app use, the number of hospitalizations, and survival rates. In addition, a satisfaction survey and an interview were conducted with the IG.

Results
The median use of the mobile app was 21 (IQR 16-28) days. At the end of the follow-up, the Borg dyspnea scale was significantly lower in patients who used the mobile app for HO therapy monitoring (mean 0.6, SD 0.8 vs mean 4.1, SD 1.4; P=.001). Regarding the impact of COPD on quality of life, as measured by the CAT, no differences were found in the scores between baseline and end-of-follow-up within the control group. However, a significant decrease was observed in the IG (baseline median CAT 27, IQR 23-31 vs final median CAT 22, IQR 14-28; P<.001). In addition, the CAT score was significantly higher in patients receiving conventional monitoring compared with those monitored with the mobile app (median 30, IQR 23-32 vs median 22, IQR 14-28; P=.02).

Conclusions
The use of the mobile app, AppO2 (SINCO), designed for the clinical monitoring of patients with COPD and HO therapy, is associated with improved quality of life. In addition, the app is highly accepted by users, promotes self-care, and fosters patient confidence in managing their own condition.

Trial Registration
ClinicalTrials NCT04820790; https://clinicaltrials.gov/study/NCT04820790

International Registered Report Identifier (IRRID)
RR2-https://doi.org/10.1186/s12875-021-01450-8
Población carretera y sus animales de compañía: desafíos para el acompañamiento pedagógico desde la política pública en Bogotá
Authors: Jiménez-Pinzón Andrea Mireya , Sánchez Cogollo Gineth Paola , Chiguasuque Gonzalez Vanessa Catalina , Arias Solano Laura Ximena , Giraldo Silva María Paula 
Published: January 2025

El presente articulo refiere el devenir investigativo de un proyecto que se circunscribe entre el Semillero NEST de la Universidad de La Salle y el Instituto Distrital de Protección y Bienestar Animal- IDPYBA de la Alcaldía Mayor de Bogotá, a partir de la necesidad institucional para identificar las características de la población carretera en dos localidades de la ciudad y las necesidades de sus animales de compañía, con el propósito de desarrollar estratégicas a futuro para el fortalecimiento, seguimiento y acompañamiento pedagógico en favor del bienestar animal. En este contexto, se delimita como objetivo de indagación el caracterizar la población carretera y sus animales de compañía en las localidades de Kennedy y Los Mártires; orientado metodológicamente como un estudio mixto, apoyado en técnicas de observación y encuesta, aplicadas a dicha población que tiene bajo su cuidado animales de compañía de diversas especies. A nivel de hallazgos principales de la investigación, se identificó que un 40% es población migrante venezolana y el restante colombiana procedente de diferentes regiones del país; en cuanto a las especies animales de mayor tenencia en escala de mayor a menor son caninos, felinos, gallos y gallinas; y en cuanto al vínculo que establecen a nivel interespecie consideran a sus animales como miembros de la familia, donde especialmente son los perros quienes los acompañan en su labor diaria recorriendo la ciudad. Lo anterior, define los principales desafíos de la política pública en la ciudad, para el abordaje pedagógico a realizar con la población carretera a fin de garantizar sus derechos y el de animales de compañía.
Survei Literasi Jasmani Peserta Didik SD Negeri 10 Banjar di Kecamatan Banjar Kabupaten Buleleng Tahun Pelajaran 2023/2024
Authors: Waruwu Calvin Candra Christian , I Gede Suwiwa  , Peby Gunarto  
Published: January 2025

Penelitian ini dilaksanakan pada peserta didik kelas IV, V, dan VI SD Negeri 10 Banjar di Kecamatan Banjar, Kabupaten Buleleng pada tanggal 12 Desember 2023 - 27 April 2024 untuk mengetahui tingkat kemampuan Literasi Jasmani. Jenis penelitian ini adalah penelitian deskriptif kuantitatif dengan metode survei. Literasi, termasuk literasi jasmani, adalah keterampilan dasar penting yang mendukung partisipasi aktif dalam berbagai aspek kehidupan. Literasi jasmani melibatkan motivasi, kepercayaan diri, kompetensi jasmani, pengetahuan, dan pemahaman untuk terlibat dalam aktivitas jasmani seumur hidup. Data diperoleh melalui kuesioner PLKQ (Physical Literacy Knowledge Questionnaire). Berdasarkan hasil analisis data dan pembahasan, dapat disimpulkan bahwa tingkat kemampuan literasi jasmani peserta didik SD Negeri 10 Banjar di Kecamatan Banjar, Kabupaten Buleleng, Tahun Pelajaran 2023/2024 berada pada kategori tinggi. Hal ini ditunjukkan dengan rata-rata hasil kuesioner literasi jasmani peserta didik sebesar 63 (79%) yang berada pada kategori tinggi. Hasil yang diperoleh dari kuesioner menunjukkan bahwa banyak peserta didik yang memiliki pemahaman tentang literasi jasmani. Pada penelitian ini diharapkan tidak ada lagi orang yang malas untuk melakukan aktivitas jasmani dan menjadikannya sebagai kebiasaan. Untuk memperoleh hidup sehat tidak perlu harus aktivitas yang berat dan susah, dengan selalu rutin dan konsisten melakukan aktivitas sederhana sangat lebih baik seperti program jalan kaki setiap hari.
Gerak Dasar Anak Berkebutuhan Khusus Tunalaras Di Sekolah Dasar
Authors: Zebua Syukur Damai , Simatupang Nurhayati , Siregar Samsuddin , Dewi Rahma , Sinulingga Albadi , Hidayat Rizky 
Published: January 2025

Tunalaras merupakan anak yang berkelainan perilaku atau anak yang mengalami gangguan emosi dan tingkah laku sehingga kurang menyesuaikan diri dengan baik, baik terhadap lingkungan keluarga, sekolah, maupun masyarakat. Tujuan penelitian ini untuk menganalisis gerak dasar anak tunalaras dalam mengikuti pembelajaran pendidikan jasmani di Sekolah Dasar. Penelitian ini merupakan penelitian deskriptif kuantitatif. Subjek penelitian yaitu peserta didik Sekolah Dasar yang berjumlah 50 orang dengan rincian 25 orang putra dan 25 orang putri. Metode yang digunakan dalam penelitian ini adalah survey dengan teknik pengumpulan data yang digunakan memakai kuesioner. Hasil analisis data dan pembahasan dapat diketahui bahwa tingkat kesulitan siswa pada pelaksanaan pembelajaran gerak dasar di sekolah dasar kota medan berada pada kategori “sangat tinggi” sebesar 6% (3 siswa), “tinggi” sebesar 76% (38 siswa), “cukup” sebesar 18% (9 siswa), “rendah” sebesar 0% (0 siswa), dan “sangat rendah” sebesar 0% (0 siswa). Disimpulkan bahwa kebanyakan siswa di sekolah dasar Kota Medan mengalami kesulitan yang besar dalam belajar gerak dasar. Sebagian besar siswa merasa kesulitannya tinggi, bahkan ada yang merasa sangat tinggi. Sebaliknya, tidak ada siswa yang merasa kesulitannya rendah atau sangat rendah. Implikasi penelitian ini menunjukkan adanya tantangan besar dalam pembelajaran gerak dasar yang perlu diatasi oleh guru PJOK maupun guru lain dan pihak sekolah bekerja sama dengan orangtua siswa untuk meningkatkan efektivitas pembelajaran di Sekolah Dasar.
Implementasi Outdoor Education Terhadap Hasil Belajar PJOK Materi Kebugaran Jasmani Peserta Didik Kelas VII SMP
Authors: Dani Wiradhika Putra Pande Made , Kadek Yogi Parta Lesmana  , Hendra Mashuri  
Published: January 2025

Penelitian ini didasari karena adanya peserta didik yang tidak tuntas pada mata pelajaran PJOK materi kebugaran jasmani pada kelas 7 SMP. Tujuan dari penelitian ini adalah untuk meningkatkan hasil belajar mata pelajaran PJOK materi kebugaran jasmani peserta didik kelas 7 SMP dengan menggunakan metode pembelajaran Outdoor Education berbasis trekking dan outbound. Metode penelitian yang digunakan adalah penelitian tindakan kelas dengan subjek penelitian adalah peserta didik kelas 7 SMP. Data hasil belajar dikumpulkan dengan cara tes hasil belajar dan lembar observasi untuk aspek kognitif dan aspek afektif sedangkan aspek psikomotor menggunakan Tes Kebugaran Siswa Indonesia (TKSI). Hasil penelitian menunjukkan adanya peningkatan hasil belajar pada siklus I meskipin masih ada peserta didik yang tidak tuntas, sehingga dilanjutkan pada siklus II yang menghasilkan seluruh peserta didik telah mencapai ketuntasan pasa materi kebugaran jasmani pada mata pelajaran PJOK. Dapat disimpulkan bahwa outdoor education dapat meningkatkan hasil belajar PJOK materi kebugaran jasmani peserta didik kelas 7.