bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy of partial embolization of splenic artery in patients after hemorrhage of portal genesis
Authors: Petrushenko V. V. , Grebeniuk D. І. 
Published: September 2022

Objective. To assess the efficacy of partial embolization of splenic artery in patients after hemorrhage of portal genesis.
Materials and methods. Into the investigation 39 patients with verified diagnosis of hepatic cirrhosis, complicated by portal hypertension and hemorrhage from widened varicose esophageal veins, were included. Into the first group (n=17) were included the patients, to whom endoscopic ligature of bleeding varicosities and partial embolization of splenic artery performed; into the second one (n=22) - patients, to whom independent endoscopic ligature of bleeding varicosities performed. The levels of laboratory indices, characterizing hepatic functional state, were assessed monthly.
Results. In the first group upon a time a progressive statistically significant improvement of all indices investigated was noted. In the second group a statistically significant improvement of all indices was observed in a period between first and second visit. In further times the changes did not have a statistical significance. While conduction of multifactorial analysis of variance for investigation of embolia impact on the pigmentary metabolism and the system of hemostasis indices a trustworthiness of this impact had grown up upon a time and on the fourth visist became statistically significant. While investigation of the embolization impact on the level of hepatic enzymes and the proteins metabolism indices the trustworthiness of the dependence have been grown upon a time as well, but its gaining of statistical significance was observed on the third visit already.
Conclusion. Postoperative period after performance of partial embolization of splenic artery in patients, suffering hemorrhage of portal genesis, is characterized by positive dynamics of laboratory indices in hepatic functional state.
Skeletal polytrauma: prognostication and prophylaxis of embolic complications
Authors: Potapchuk Yu. O. , Budniuk O. O. , Volodychev D. S. 
Published: September 2022

Objective. Improvement of the treatment results in injured persons with skeletal polytrauma.
Materials and methods. In the investigation 240 patients, suffering skeletal polytrauma, took part. In the Admittance-Diagnostic Department and the Department of Intensive Therapy various scales of assessment were used for objectivisation of its state of severity in the injured persons.
Results. The main risk factors for the venous thromboembolism were established in accordance to results of the investigation conducted: skeletal trauma (sensitivity 85%), durable bed-rest regime (sensitivity 94%), untimely surgical osteosynthesis (sensitivity 96%), severity of state – assessment in accordance to shortened scale of damages of 3 points and higher, in accordance to the injury severity scale of 16 points and higher (sensitivity 88%), non-compliance for the pharmacological thrombo-prophylactic regime (sensitivity 94%).
Conclusion. Basing on the results obtained, a clinical route of the medical help delivery for patients, suffering skeletal polytrauma, was introduced into the practice, what have permitted to lower the rate of venous thromboembolism from 25.8 to 15% (χ2 =13.07, p=0.001), and the rate of the fat embolism syndrome - from 19.2 t0 3.3% (χ2 =15.07, p=0.001).
Microbiological aspects of peritonitis
Authors: Karol I. V. 
Published: September 2022

Objective. To investigate pathogens in peritonitis.
Materials and methods. In 2021 yr in Department of Surgery of Brovary Multidisciplinary Clinical Hospital were treated 360 patients with an acute peritonitis of various genesis: 186 (51.7%) women and 174 (48.3%) men.
Results. In the patients 391 strains of microorganisms, which are optionally-anaerobic and aerobic of Gram-negative and Gram-positive pathogens were isolated: Escherichia coli – in 144 (36.8%), Streptococcus spp. – 52 (13.3%), Enterococcus faecalis – 47 (12.0%), Staphylococcus aureus – 37 (9.5%), Klebsiella pneumoniae – 31 (7.9%), Citrobacter – 25 (6.4%), Staphylococcus haemolyticus – 23 (5.9%), Pseudomonas aeruginosa – 14 (3.6%), Acinetobacter baumannii – 13 (3.3%), and Proteus mirabilis – 5 (1.3%) strains.
Conclusion. Majority of microorganisms, isolated in patients, suffering peritonitis, was characterized by significant antibiotic resistance. Most frequently Escherichia coli was sowed – 36.8%. All strains of Escherichia coli isolated were resistant to vancomycine, clindamycine and linezolide.
Experimental assessment and comparative analysis of efficacy for modified method of cellular therapy in chronic wounds on background of diabetes mellitus
Authors: Gramatiuk S. M. , Ivanova Yu. V. , Кryvoruchko I. A. , Goloborodko M. M. , Miasoiedov K. V. , Mіnukhin D. V. , Shevchenko O. M. 
Published: September 2022

Objective. Determination of efficacy of the cellular therapy modified method in chronic wounds on background of diabetes mellitus, comparing with standard and new methods of treatment in experiment.
Materials and methods. Experimental investigations were conducted on 30 adult male rats of a Wistar line, in which diabetes mellitus was experimentally simulated. Full-thickness square wound was used as experimental pattern. In the animals of group A (control) the wounds were processed with 0.05% solution of chlorhexidine bigluconate and the hydrohel bandages put on (standard of treatment). To the group B animals photodynamic therapy was conducted, and processes of regeneration were stimulated with the help of the mesenchymal stem cells application. To the group C animals the wounds bottom and edges were infiltrated with suspension of autologous mesenchymal stem cells for active regeneration after conduction of photodynamic therapy.
Results. Best healing of the wounds while application of photodynamic therapy and injections of mesenchymal stem cells was noted: on the 5th day from the treatment beginning the wounds square reduction have appeared the most – 71.9%, while application of mesenchymal stem cells this index have constituted 61.6%, and while standard treatment – 36.0%.
Conclusion. Treatment of chronic wounds on background of diabetes mellitus, using photodynamic therapy and injections of mesenchymal stem cells, have demonstrated essentially better results, than after standard method. Application of mesenchymal stem cells into the wound, the results of which were compared with results of their injectional introduction, may be recommended as alternative, if immediate injections of mesenchymal stem cells into the tissues over the wound are impossible.
Peculiarities of lymphotropic antibioticotherapy in a combat trauma of abdominal organs (clinic-experimental investigation)
Authors: Duzhyi І. D. , Shimko V. V. , Pyatikop G. І. , Kononenko M. G. , Oleshchenko G. P. , Al Yamani Navras D. A. 
Published: September 2022

Objective. Studying of impact of regional lymphotropic antibacterial therapy on various abdominal organs and application of the results in a combat abdominal trauma.
Materials and methods. In the experiment accumulation of ceftriaxone in various abdominal organs was investigated, and detected by dimensions of the development zone delay in laboratory culture of E. coli in 1 – 2 h regional lymphotropic introduction of the preparation in a daily dose. Laboratory animals (rabbits) were withdrawn from the experiment, using overdosing of ketamine. After obtaining of specimen from certain organs, of them homogenate was processed and it was introduced into agar-agar, on which E. coli was cultivated. Separately, pure antibiotic (control) was introduced into the bacterial development zone as well. In a day the dimensions of the development zone delay in a test-culture was calculated, in accordance to which the level of accumulation of antibiotic was revealed.
Results. The biggest dimensions of the development zone delay of E.coli were registered after antibiotic introduction into paravertebral and iliac zones, what have witnessed its maximal accumulation, accordingly, in gastric and pancreatic gland, the small bowel, coecum, sigmoid colon and the small omentum, and peritoneal specimen. After intramuscular injection of the antibiotic the dimensions of the development zone delay of E.coli have appeared minimal, witnessing practically absent accumulation of the preparation in specimen of the organs investigated.
Conclusion. Accumulation of ceftriaxone in various organs in different inhibitory dose, concerning development of E. coli, witnesses the necessity to use the regional paths of lymphotropic introduction of antibiotic into certain abdominal zone of purulent-inflammatory process. Intramuscular introduction of antibiotic is not expedient in such inflammatory processes.
De guachichiles a boçalos: la reinvención e integración de los indios del río Blanco a la estructura de la Monarquía Hispana.
Authors: Gutiérrez Cañada Diana Xóchitl 
Published: September 2022

En el presente texto se centra en los indios boçalos quienes habitaron en el área de río Blanco al sur de la jurisdicción administrativa del Nuevo Reino de León. Aunque dentro de la historiografía local se hace mención de dichos indios hasta 1648 cuando se da a conocer el conflicto de la jurisdicción eclesiástica entre la Custodia de Rioverde y del Convento de Charcas, siendo los primeros el contacto temprano con los indios carriones habitantes en la zona y otras naciones, y los segundos tendrían conocimiento de ellos posteriormente, haciendo énfasis que dichos indios bajarían para contactarse con los misioneros de Charcas en la hacienda de Matehuala por ser olvidados por los de Rioverde. La cuestión aquí no es el conflicto eclesiástico per se, sino el rastrear las primeras menciones de los indios boçalos y proponer una interpretación de su ser. Dicha propuesta radica en identificarlos como un grupo perteneciente a la nación guachichil que tuvo que adaptarse a su contexto histórico y reinventarse o, en su defecto, se vieron obligados a reconfigurar su estructura político-social e inclusive tomar un nombre puesto por los hispanos mediante transferencias culturales que adquirieron ante el discurso de dominación proveniente de la Monarquía Hispánica.
An assessment of cervical ripening with evening primrose oil: An obstetrical review
Authors: Zubaida Masood  , Fauzia Ali  , Rahilla Imtiaz  , Aisha Khatoon  , Mehwish Fatima  , Jarry Masood  
Published: September 2022

Objective: To compare cervical ripening in women having evening primrose oil with those not taking it. Study Design: Retrospective Cohort study. Setting: Department of Obs & Gynae, Abbasi Shaheed Hospital, Karachi. Period: July 2018 to April 2021. Material & Method: Patients were divided into 2 groups, one having evening primrose oil (EPO) 1gm twice daily from 37 weeks till labor, given by her previous birth attendant. Another group was without using evening primrose oil. Both were examined for cervical ripening by bishop score, length of labour and then for need for cesarean section. Statistical plan: SPSS 20. Results: BISHOP score for EPO group (6.1) vs non-EPO group (4.3) was statistically significant (p-value < 0.001). EPO have soft cervical consistency (73.5%), followed by medium (10.2%) and firm (16.3%) while non EPO have firm consistency (41.2%) followed by soft (37.3%) and medium (21.6%). The differences was statistically significant (p-value=0.001). The average length of labor for EPO group was 7.7 hours (±2.5 SD) and Non-EPO was 8.4 hours (±2.4 SD), statistically insignificant. The mode of delivery wasn’t statistically significantly different between two groups. Conclusion: EPO tend to have soft cervical consistency. However mode of delivery between EPO group and Non-EPO group did not have any significant difference.
PENYULUHAN ERGONOMI PADA PEMBELAJARAN DARING DI FAKULTAS KESEHATAN UNIVERSITAS MUHAMMADIYAH GRESIK
Authors: Inayah Zufra , Budiono Nugrahadi Dwi Pasca , Mayandari Wahidah Romadloni , Nisa Kholisatun 
Published: September 2022

Keadaan new normal menuntut pembelajaran dalam jaringan (daring) sebagai solusi dalam pencapaian pembelajaran yang optimal. Keberhasilan dalam pembelajaran daring harus diimbangi dengan pengetahuan ergonomi sehingga tidak menimbulkan keluhan nyeri pada otot rangka, kelelahan mata dan kerusakan mata, kecemasan dan stress serta resiko obesitas. Sehingga kegiatan penyuluhan ini bertujuan untuk peningkatan pengetahuan ergonomi pada pembelajaran daring. Metode menggunakan pendekatan waktu cross sectional dengan populasi sejumlah 189 mahasiswa. Analisis uji yang dipakai T-Test Paired. Pengetahuan ergonomi pada mahasiswa setelah dilakukan penyuluhan mengalami peningkatan yang signifikan p=0,000 dan pada materi isu ergonomi hampir semua 98,36% menjawab dengan benar dan tips posisi ergonomis dalam daring hampir semua 90,16 % menjawab benar. Diharapakan pembelajaran melalui daring dapat terlaksana dengan baik, sehingga keluhan nyeri otot rangka, kelelahan mata dan stress dapat dicegah dengan baik.
IMPACTO DA PANDEMIA NA SAÚDE MENTAL DOS DISCENTES DE ENFERMAGEM NO CONTEXTO DA COVID-19
Authors: Macêdo Daianny Paes Landim , Silva Dayla Damires Nogueira Santos , Magalhães Juliana Macêdo , Batista Pedro Venicius de Sousa , Amorim Fernanda Cláudia Miranda , Carvalho Cláudia Maria Sousa de , Gonçalves Bruno Macêdo 
Published: September 2022

Objetivo: Investigar os impactos da pandemia da COVID-19 na saúde mental dos discentes de enfermagem e avaliar a relação entre o evento e os indicadores para transtorno de estresse pós-traumático (TEPT). Método: estudo exploratório, analítico, transversal, com abordagem quantitativa. A amostra estudada foi constituída por 164 estudantes de uma instituição de ensino superior privada, matriculado no curso de Enfermagem, convidado por meio eletrônico, que responderam ao questionário on-line sobre dados sociodemográficos, percepção de risco pela pandemia COVID-19 e sintomas de estresse pós-traumático avaliados pela Impact of Event Scale (IES-R) em sua versão brasileira validada. Resultados: A maioria dos participantes eram da faixa etária de 18 a 23 anos (70,8%), do sexo feminino (91,5%), sem filhos (86%), residem com 2 a 4 pessoa (75%). 51,2% apresentam indicação alta para TEPT, 14,0% apresentam preocupação clínica para TEPT. Houve associação do escore da IES-R com a idade, quantidade de filhos e quantidade de pessoas com quem reside. Conclusão: O evento da pandemia da Covid-19 provocou um impacto na saúde mental dos discentes de Enfermagem, com uma elevada classificação de participantes com indicação alta para TEPT. Esses dados são importantes para futuras intervenções psicológicas e pedagógicas entre estudantes.
A Summary of Conscience in Reproductive Health Care: Prioritizing Patient Interests
Authors: McLeod Carolyn 
Published: September 2022

At the 2022 Central American Philosophical Association meeting (Chicago, Illinois, February 23–26), there was an Author-Meets-Critics session on Carolyn McLeod’s (2020 ) book, Conscience in Reproductive Health Care: Prioritizing Patient Interests. The event was organized and chaired by Heather Stewart and sponsored by the APA Committee on the Status of Women and Kate Norlock, chair of that committee. There were four speakers, including McLeod and three “critics”: Javiera Perez Gomez, Alison Reinheld, and Jennifer Parks, who were all generous enough to provide McLeod with their comments beforehand. The sessions occurred over Zoom even though some speakers were present in person at the conference. McLeod kicked things off by providing a summary of her book, which was then followed by critical (and supportive!) comments by the critics in the order in which they’re named above. McLeod responded to their remarks and then Stewart led a Q&A session with our small but lively and intelligent audience. The content of what was said has been reproduced here.
Budaya Atoni Pah Meto dalam Resolusi Konflik Masyarakat Perbatasan Indonesia dan Timor Leste
Authors: Binsasi Heribertus 
Published: September 2022

Penelitian ini dilatarbelakangi oleh adanya konflik masyarakat perbatasan Indonesia dan Timor Leste dalam perebutan lahan pada titik Un-Surveyed Segment dan Un-Resolved Segment. Tujuan penelitian ini adalah untuk mengkaji budaya Atoni Pah Meto dalam resolusi konflik masyarakat perbatasan Indonesia dan Timor Leste. Metode yang digunakan dalam penelitian ini adalah kualitatif dengan pendekatan studi kasus. Subyek penelitian ini adalah tokoh adat, tokoh masyarakat dan tokoh agama di Kabupaten Timor Tengah Utara dan Distrik Oecusse. Teknik pengumpulan data menggunakan observasi, wawancara, dan dokumentasi. Teknik analisis data menggunakan reduksi data, penyajian data dan penarikan kesimpulan Hasil penelitian menunjukan bahwa, Budaya Atoni Pah Meto dalam resolusi konflik masyarakat perbatasan Indonesia dan Timor Leste pada titik Un-Surveyed Segment dan Un-Resolved Segment dilakukan dengan beberapa tahapan yaitu 1) kedua kelompok masyarakat bertemu dan saling menyuguhkan sirih pinang (maloe mamat); 2) dialog bersama (tamolok tabua); 3) ritual adat (natone); 4) sumpah adat (tiun menu).
A system of anatomical triangles defining dissection routes to brainstem cavernous malformations: definitions and application to a cohort of 183 patients
Authors: Benner Dimitri , Hendricks Benjamin K. , Benet Arnau , Graffeo Christopher S. , Scherschinski Lea , Srinivasan Visish M. , Catapano Joshua S. , Lawrence Peter M. , Schornak Mark , Lawton Michael T. 
Published: September 2022

OBJECTIVE
Anatomical triangles defined by intersecting neurovascular structures delineate surgical routes to pathological targets and guide neurosurgeons during dissection steps. Collections or systems of anatomical triangles have been integrated into skull base surgery to help surgeons navigate complex regions such as the cavernous sinus. The authors present a system of triangles specifically intended for resection of brainstem cavernous malformations (BSCMs). This system of triangles is complementary to the authors’ BSCM taxonomy that defines dissection routes to these lesions.

METHODS
The anatomical triangle through which a BSCM was resected microsurgically was determined for the patients treated during a 23-year period who had both brain MRI and intraoperative photographs or videos available for review.

RESULTS
Of 183 patients who met the inclusion criteria, 50 had midbrain lesions (27%), 102 had pontine lesions (56%), and 31 had medullary lesions (17%). The craniotomies used to resect these BSCMs included the extended retrosigmoid (66 [36.1%]), midline suboccipital (46 [25.1%]), far lateral (30 [16.4%]), pterional/orbitozygomatic (17 [9.3%]), torcular (8 [4.4%]), and lateral suboccipital (8 [4.4%]) approaches. The anatomical triangles through which the BSCMs were most frequently resected were the interlobular (37 [20.2%]), vallecular (32 [17.5%]), vagoaccessory (30 [16.4%]), supracerebellar-infratrochlear (16 [8.7%]), subtonsillar (14 [7.7%]), oculomotor-tentorial (11 [6.0%]), infragalenic (8 [4.4%]), and supracerebellar-supratrochlear (8 [4.4%]) triangles. New but infrequently used triangles included the vertebrobasilar junctional (1 [0.5%]), supratrigeminal (3 [1.6%]), and infratrigeminal (5 [2.7%]) triangles. Overall, 15 BSCM subtypes were exposed through 6 craniotomies, and the approach was redirected to the BSCM by one of the 14 triangles paired with the BSCM subtype.

CONCLUSIONS
A system of BSCM triangles, including 9 newly defined triangles, was introduced to guide dissection to these lesions. The use of an anatomical triangle better defines the pathway taken through the craniotomy to the lesion and refines the conceptualization of surgical approaches. The triangle concept and the BSCM triangle system increase the precision of dissection through subarachnoid corridors, enhance microsurgical execution, and potentially improve patient outcomes.
Development and validation of a new disease-specific quality of life instrument for sporadic vestibular schwannoma: the Mayo Clinic Vestibular Schwannoma Quality of Life Index
Authors: Carlson Matthew L. , Lohse Christine M. , Link Michael J. , Tombers Nicole M. , McCaslin Devin L. , Saoji Aniket A. , Hutchins Melanie , Yost Kathleen J. 
Published: September 2022

OBJECTIVE
Facial nerve function, hearing preservation, and tumor control have been the primary benchmarks used to assess vestibular schwannoma (VS) outcomes. Acknowledging the frequent discrepancy between what physicians prioritize and what patients value, there has been increasing prioritization of patient-reported outcome measures when evaluating the impact of VS diagnosis and its treatment. Motivated by reported limitations of prior instruments used to assess quality of life (QOL) in patients with VS, the authors describe the development and validation of a new disease-specific QOL measure: the Vestibular Schwannoma Quality of Life (VSQOL) Index.

METHODS
The content development phase comprised identification of clinically important domains and prioritization of feelings or concerns individuals with VS may have. The validation phase encompassed determining how items were grouped into domains and eliminating redundant items. Both phases leveraged data from cross-sectional and longitudinal surveys, expertise from a multidisciplinary working group, and patients with a broad range of experiences with VS (n = 42 during content development and n = 263 during validation). Domain scores from the new instrument were assessed for reliability and correlation with other measures of similar constructs.

RESULTS
The VSQOL Index consists of 40 items that evaluate the impact of VS diagnosis and its management on QOL, treatment satisfaction, and employment and is estimated to take 8–10 minutes to complete. Domain scores range from 0 (worst) to 100 (best) and demonstrate excellent psychometric properties, including content, construct, and convergent validity and both internal consistency (Cronbach’s alphas 0.83 to 0.91) and test-retest reliability (reliability coefficients 0.86 to 0.96).

CONCLUSIONS
The VSQOL Index is a valid and reliable measure that overcomes several limitations of prior instruments, including omission or underrepresentation of domains that frequently impact well-being, such as pain, cognition, satisfaction or regret surrounding treatment decisions, and occupational limitations, to comprehensively evaluate the impact of VS diagnosis or its treatment on QOL.