bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interspecific variation in the temperature response of mesophyll conductance is related to leaf anatomy
Authors: Huang Guanjun , Zhang Qiangqiang , Yang Yuhan , Shu Yu , Ren Xifeng , Peng Shaobing , Li Yong 
Published: August 2022

SUMMARYAlthough mesophyll conductance (gm) is known to be sensitive to temperature (T), the mechanisms underlying the temperature response of gm are not fully understood. In particular, it has yet to be established whether interspecific variation in gm–T relationships is associated with mesophyll anatomy and vein traits. In the present study, we measured the short‐term response of gm in eight crop species, and leaf water potential (Ψleaf) in five crop species over a temperature range of 15–35°C. The considered structural parameters are surface areas of mesophyll cells and chloroplasts facing intercellular airspaces per unit leaf area (Sm and Sc), cell wall thickness (Tcw), and vein length per area (VLA). We detected large interspecific variations in the temperature responses of gm and Ψleaf. The activation energy for gm (Ea,gm) was found to be positively correlated with Sc, although it showed no correlation with Tcw. In contrast, VLA was positively correlated with the slope of the linear model of Ψleaf–T (a), whereas Ea,gm was marginally correlated with VLA and a. A two‐component model was subsequently used to model gm–T relationships, and the mechanisms underlying the temperature response of gm are discussed. The data presented here indicate that leaf anatomy is a major determinant of the interspecific variation in gm–T relationships.
NLO multijet merging for Higgs production beyond the VBF approximation
Authors: Chen Tinghua , Figy Terrance M. , Plätzer Simon 
Published: August 2022

AbstractWe present results of the simulation of electroweak Higgs boson production at the Large Hadron Collider using both the NLO multijet merging and NLO matching frameworks provided by the general purpose event generator . For the simulation of the hard scattering processes, we use the library for the full calculation and for the approximate calculation to compute the $$2\rightarrow h+n$$

2
→
h
+
n

amplitudes at tree-level with $$n=2,3,4$$

n
=
2
,
3
,
4

and at one-loop with $$n=2,3$$

n
=
2
,
3

.
Reaching the bubble may not be enough: news media role in online political polarization
Authors: Kobellarz Jordan K. , Broćić Miloš , Graeml Alexandre R. , Silver Daniel , Silva Thiago H. 
Published: August 2022

AbstractPolitics in different countries show diverse degrees of polarization, which tends to be stronger on social media, given how easy it became to connect and engage with like-minded individuals on the web. A way of reducing polarization would be by distributing cross-partisan news among individuals with distinct political orientations, i.e., “reaching the bubbles”. This study investigates whether this holds in the context of nationwide elections in Brazil and Canada. We collected politics-related tweets shared during the 2018 Brazilian presidential election and the 2019 Canadian federal election. Next, we proposed an updated centrality metric that enables identifying highly central bubble reachers, nodes that can distribute content among users with diverging political opinions—a fundamental metric for the proposed study. After that, we analyzed how users engage with news content shared by bubble reachers, its source, and its topics, considering its political orientation. Among other results, we found that, even though news media disseminate content that interests different sides of the political spectrum, users tend to engage considerably more with content that aligns with their political orientation, regardless of the topic.
Efficacy and Safety of Dapagliflozin versus Liraglutide in Patients with Overweight or Obesity and Type 2 Diabetes Mellitus: A Randomised Controlled Clinical Trial in Tianjin, China
Authors: Zhaohu Hao , Xiao Huang , Hailin Shao , Feng He 
Published: August 2022

Objective. We aimed to clarify the efficacy of dapagliflozin versus liraglutide in patients with overweight or obesity and type 2 diabetes mellitus (T2DM) at the beginning of the coronavirus disease 2019 (COVID-19) pandemic. Methods. T2DM patients with overweight or obesity who visited the Metabolic Disease Management Center at Tianjin Fourth Central Hospital from October 2019 to January 2020 were recruited and randomised to receive dapagliflozin or liraglutide for 24 weeks. Changes in blood glucose and lipid levels, blood pressure, and body weight, as well as the occurrence of hypoglycaemia and other adverse events, were compared. Results. 309 patients completed the study (143 in liraglutide group and 166 in dapagliflozin group). After 24 weeks, HbA1c, fasting blood glucose (FPG), and 2 h postprandial blood glucose (2hPG) levels significantly decreased from

8.80
%
±
1.41
%

to

7.02
%
±
1.05
%

,

10.41
±
3.13

to

7.59
±
2.16

mmol/L, and

17.90
±
4.39

to

10.12
±
2.47

mmol/L, respectively, in the dapagliflozin group, and from

8.92
%
±
1.49
%

to

6.78
%
±
1.00
%

,

10.04
±
2.99

to

7.20
±
1.63

mmol/L, and

17.30
±
4.39

to

10.13
±
4.15

mmol/L, respectively, in the liraglutide group. Changes in HbA1c, FPG, and 2hPG levels between groups were not significantly different. Systolic blood pressure (SBP) and low-density lipoprotein cholesterol (LDL-C) level significantly decreased from

144.1
±
19.1

to

139.7
±
16.2

mmHg (

p
=
0.001

) and from

3.21
±
0.94

to

2.98
±
0.89

mmol/L (

p
=
0.014

), respectively, in the dapagliflozin group. After COVID-19 outbreak, the number of patients taking sleep-promoting drugs increased from 4.9% to 9.4% (

p
=
0.029

). Conclusions. Liraglutide and dapagliflozin had strong hypoglycaemic effects in patients with overweight or obesity and T2DM at the beginning of the COVID-19 pandemic. Dapagliflozin may be beneficial in improving SBP and LDL-C levels; however, further research is warranted.
Il nome della rosa’s Translations in the Chinese Language
Authors: Ottaviano Ludovica 
Published: August 2022

Abstract
In 1980, Umberto Eco’s first novel Il nome della rosa was published in Italy and has quickly had global resonance, entering China by the late 1980s. Since then, six translations have been published in the Chinese language, including two issued by Taiwanese translators. It is interesting to observe how each version is able to refract the socio-cultural contexts of the translators, depending on the aspirations and cultural images created in the different periods and geographic areas. We need also consider that, especially in the case of Eco’s novels, the translators had to not only deal with the different needs and expectations of their readers but also imagine a ‘new model reader’, just as Eco did. Therefore, this paper aims at confronting the six different translated versions, by identifying the new model readers imagined by the translators, considering their own expectations, knowledge, and cultural context.
Prevalence of Body Dysmorphic Disorder in an Otolaryngology-Head and Neck Surgery Clinic
Authors: Moroco Annie E. , Daher Ghazal S. , O’Connell Ferster Ashley P. , Lighthall Jessyka G. 
Published: August 2022

Objective: To analyze the prevalence of body dysmorphic disorder (BDD) in a general otolaryngology population presenting to an outpatient clinic. Study Design: Prospective prevalence study. Setting: Single tertiary academic otolaryngology clinic. Subject and Methods: New patients over 18 years of age who presented to an academic otolaryngology clinic between August 2018 and May 2021 completed a questionnaire including demographic questions and the validated Body Dysmorphic Disorder Questionnaire (BDDQ). Data collected from the questionnaires were analyzed to assess demographics and prevalence of BDD in an otolaryngology clinic. Results: Of the 242 patients queried, 15 patients screened positive for BDD. The screened prevalence of BDD was determined to be 6.2%. None of the patients had previously been diagnosed with BDD. The prevalence of prior mental health diagnoses was 34.3%. These patients had initially presented for a variety of otolaryngologic concerns and had pre-existing diagnoses of anxiety, depression, obsessive-compulsive, bipolar and eating disorders. Conclusion: The prevalence of BDD in our population of new patients presenting to an academic otolaryngology practice (6.2%) is higher than that of the general population (1.9%).
Preparation of Al/AlN composites by in-situ reaction in the nitridation-induced self-forming process
Authors: Kim Jungjoon , Park Jooyoung , Shim Cheol-Hwee , Ahn Jae-Pyong , Choi Hyunjoo , Lee Kon-Bae 
Published: August 2022

Recently, we developed and reported an easy and cost-effective process called nitridation-induced self-forming Al composites (NISFAC) for manufacturing aluminum matrix composites from Al powder. In this process, AlN is formed by an in situ reaction between Al powder and nitrogen gas, and Al/AlN composites are self-sintered at temperatures below the melting point of aluminum because of the thermal energy released by the nitridation reaction of the Al powder. Because AlN is formed by an in situ reaction in the Al matrix, it is not only chemically stable, but also beneficial in terms of its wettability with the matrix. In this study, we prepared Al/AlN composites using the NISFAC process by increasing the amount of ex-situ added AlN reinforcement. The coefficient of thermal expansion (CTE) was effectively reduced by increasing the volume fraction of AlN, which was significantly lower than the theoretically expected value; a CTE of ∼10.8 × 10−6/°C could be achieved by adding only 20 vol.% of AlN. This demonstrates that the in situ formation of AlN during the NISFAC process may help reduce the CTE of Al/AlN composites.
Recurrent vulvovaginal candidiasis with Candida glabrata – a management conundrum
Authors: Taghinejadi Neda , Andersson Monique I , Lord Emily 
Published: August 2022

High rates of azole-resistance and limited availability of pharmacological agents within the UK can make recurrent vulvovaginal candidiasis (RVVC) with Candida glabrata a challenging infection to treat. In this report, we describe our experience in managing C. glabrata RVVC and present the case of a patient with poor response to therapy and a protracted treatment course, spanning almost 4 years. We also highlight the need for evidence-based management protocols that consider the national availability of alternative treatments.
Interventions, Barriers, and Proposed Solutions Associated With the Implementation of a Protocol That Uses Clinical Decision Support and a Stress Biomarker Test to Identify ICU Patients at High-Risk for Drug Associated Acute Kidney Injury
Authors: Williams Victoria L. , Smithburger Pamela L. , Imhoff Allison N. , Groetzinger Lara M. , Culley Colleen M. , Burke Clayton X. , Murugan Raghavan , Lamberty Phillip E. , Mahmud Mujtaba , Benedict Neal J. , Kellum John A. , Kane-Gill Sandra L. 
Published: August 2022

Background: Damage biomarkers are helpful in early identification of patients who are at risk of developing acute kidney injury (AKI). Investigations are ongoing to identify the optimal role of stress/damage biomarkers in clinical practice regarding AKI risk prediction, surveillance, diagnosis, and prognosis. Objective: To determine the impact of utilizing a clinical decision support system (CDSS) to guide stress biomarker testing in intensive care unit (ICU) patients at risk for drug-induced acute kidney injury (D-AKI). Methods: A protocol was designed utilizing a clinical decision support system (CDSS) alert to identify patients that were ordered 3 or more potentially nephrotoxic medications, suggesting risk for progressing to AKI from nephrotoxic burden. Once alerted to these high-risk patients, the pharmacist determined if action was needed by ordering a stress biomarker test, tissue inhibitor of metalloproteinase-2-insulin-like growth factor-binding protein 7 (TIMP-2•IGFBP7). If the biomarker test result was elevated, the pharmacist provided nephrotoxin stewardship recommendations to the team. Pharmacists recorded the response to the clinical decision support alert, ordering, and interpreting the TIMP-2•IGFBP7, and information regarding clinical interventions. An alert in conjunction with TIMP-2•IGFBP7 as a strategy for AKI risk prediction and stimulant for patient care management was assessed. In addition, barriers and solutions to protocol implementation were evaluated. Results: There were 394 total activities recorded by pharmacists for 345 unique patients. Ninety-three (93/394; 23.6%) actionable alerts resulted in a TIMP-2•IGFBP7 test being ordered. Thirty-one TIMP-2•IGFBP7 results were >0.3 (31/81; 38.3%), suggesting a high-risk of progression to AKI, which prompted 191 pharmacist/team interventions. On average, there were 1.64 interventions per patient in the low-risk patients, 3.43 in high-risk patients, and 3.75 in the highest-risk patients. Conclusion and Relevance: Stress biomarkers can be used in conjunction with CDSS alerts to affect therapeutic decisions in ICU patients at high-risk for D-AKI.
The engagement of nursing and healthcare researchers with digital technologies: lessons learnt in an Australian university
Authors: Roesler Anna , Lange Belinda 
Published: August 2022

Background The use of digital technologies has expanded rapidly in recent years, particularly with the onset of COVID-19. Digital technologies have been implemented in nursing and healthcare to support necessary care. Aims This research explored how nursing and healthcare researchers engage with digital technologies, including the types of technologies, facilitators, barriers and suggested improvements to enable engagement. Methods Semi-structured interviews were conducted with 36 nursing and healthcare researchers from an Australian University. Interviews were recorded, transcribed, coded and thematically analysed using the COREQ checklist. Results Four major types of digital technologies were engaged by nursing and healthcare researchers. These included monitoring, intervention, communication and data collection and analysis technologies. The research setting provided the overarching systems and policies that could delay actions or provide necessary supports. Access to experts, good communication, sharing digital technology information, and time and funding were identified as important. Conclusion This research highlights that nursing and healthcare researchers are engaging with digital technologies but there are areas for improvement that are underpinned by the research setting and need to be considered to ensure effective use of digital technologies in nursing and healthcare research.
Pregnant women’s knowledge, attitudes, and associated factors toward physical exercise during pregnancy among those attending antenatal care at Bahir Dar city, Northwest Ethiopia
Authors: Bayisa Diriba , Waltengus Fikadu , Lake Selamawit , Wakuma Bizuneh , Bayisa Lami , Chala Merga , Regasa Misganu Teshoma , Besho Merga , Mosisa Getu 
Published: August 2022

Background: Exercise during pregnancy is among the cost-effective options that can significantly reduce the burden of chronic metabolic diseases leading to an adverse birth outcome. Despite the negative consequences of sedentary life among pregnant women, little is known about the pregnant mothers’ knowledge, attitude, and associated factors toward exercise during pregnancy in Ethiopia, particularly in the study area. Objective: To assess knowledge, attitude, and associated factors toward exercise during pregnancy among women attending antenatal care at Bahir Dar city, Northwest Ethiopia, 2020. Methodology: A health facility-based cross-sectional study design was employed among 475 pregnant women from March 12 to May 12, 2020. A systematic random sampling technique was used to select the study participants. Interviewer-administered questionnaire was used to collect the data from pregnant women attending the antenatal care unit. Data were coded and entered using Epidata version 3.1 and analyzed by Statistical Package for Social Science (SPSS) version 25. Binary and multivariable logistic regressions were used to identify possible determinants and an odds ratio was used to measure the strength of associations at a p-value of <0.05 Result: The study showed that 55.8% (95% CI: 48.45–59.12) of pregnant women were knowledgeable about benefits and contraindication of exercise during pregnancy; 53.3% (95% CI: 49.05–57.62) of them had positive attitudes toward exercise during pregnancy. Educational status adjusted odd ratio (AOR) = 3.95 (95% CI: 1.712–9.108), practicing physical exercise before becoming pregnant AOR = 3.64 (95% CI: 1.091–12.118), and women who heard about exercise during pregnancy AOR = 4.74 (95% CI: 2.563–8.756) were found to have statistically significant association with knowledge of women about exercise during pregnancy. Women who were knowledgeable about exercise during pregnancy AOR = 4.45 (95% CI: 2.39–8.29) and women who heard about exercise during pregnancy AOR = 4.2 (95% CI: 2.19–8.08) were more likely to have a positive attitude toward benefits of exercise during pregnancy. Conclusion: The level of mothers’ knowledge and attitude toward exercise during pregnancy in the study area was low. Educational status, physical exercise before pregnancy, ever heard about exercise during pregnancy were independent determinants of women’s knowledge, while ever heard and knowledgeable about exercise during pregnancy were determinants of favorable attitude toward exercise during pregnancy. Empowering women through health education about physical exercise during pregnancy should get due attention.
Metacells untangle large and complex single-cell transcriptome networks
Authors: Bilous Mariia , Tran Loc , Cianciaruso Chiara , Gabriel Aurélie , Michel Hugo , Carmona Santiago J. , Pittet Mikael J. , Gfeller David 
Published: August 2022

Abstract
Background
Single-cell RNA sequencing (scRNA-seq) technologies offer unique opportunities for exploring heterogeneous cell populations. However, in-depth single-cell transcriptomic characterization of complex tissues often requires profiling tens to hundreds of thousands of cells. Such large numbers of cells represent an important hurdle for downstream analyses, interpretation and visualization.

Results
We develop a framework called SuperCell to merge highly similar cells into metacells and perform standard scRNA-seq data analyses at the metacell level. Our systematic benchmarking demonstrates that metacells not only preserve but often improve the results of downstream analyses including visualization, clustering, differential expression, cell type annotation, gene correlation, imputation, RNA velocity and data integration. By capitalizing on the redundancy inherent to scRNA-seq data, metacells significantly facilitate and accelerate the construction and interpretation of single-cell atlases, as demonstrated by the integration of 1.46 million cells from COVID-19 patients in less than two hours on a standard desktop.

Conclusions
SuperCell is a framework to build and analyze metacells in a way that efficiently preserves the results of scRNA-seq data analyses while significantly accelerating and facilitating them.
The composition of braconid wasp communities in three forest fragments in a tropical lowland forest of Panama
Authors: Rodríguez Louise A. , Medianero Enrique 
Published: August 2022

Abstract
Background
In the last 171 years, the forests along the eastern bank of the Panama Canal have been pressured by anthropic activities. Studies of the influence of habitat fragmentation on braconid wasp communities in Central America is scarce, showing the existing information gap on these communities required to implement strategic plans for ecosystem sustainability and conservation. This study investigated how fragmentation affects braconid wasp communities in three areas in Panama City: Metropolitan Natural Park, Albrook and Corozal. Two permanent Malaise Traps were installed in the center of each fragment and were reviewed weekly from May 2019 to March 2020. Alpha and beta diversity indices and the similarity index were used to demonstrate the composition of braconid wasp communities in three forest fragments.

Results
A similarity of 94% was estimated for the subfamily composition and 74% was estimated for the morphospecies composition of wasp community in the fragments studied. Wasp subfamily and morphospecies assemblages were more similar between fragments of Albrook and Metropolitan Natural Park. Richness and abundance of braconid wasps observed were statistically different between the fragments studied.

Conclusion
Richness, abundance, and composition of braconid wasps differ among habitat fragments with high similarity between subfamilies and morphospecies. Therefore, the fragments studied can be used as stepping stones to maintain remaining populations of braconid wasp communities. Monitoring is recommended to assess the effect of fragmentation on the remaining forests.
Overlaps in olfactive signalling coupled with geographic variation may result in localised pollinator sharing between closely related Ficus species
Authors: Deng Xiaoxia , Cheng Yufen , Peng Yan-Qiong , Yu Hui , Proffit Magali , Kjellberg Finn 
Published: August 2022

Abstract
Background
In brood site pollination mutualisms, pollinators are attracted by odours emitted at anthesis. In Ficus, odours of receptive figs differ among species and the specific pollinators generally only enter figs of their host species ensuring a pre-zygotic barrier to plant interspecific hybridisation. However, field observations recorded that, in Guangdong province in China, Valisia javana hilli, the local pollinator of F. hirta, entered and reproduced successfully in the figs of the closely related F. triloba on a regular basis. We propose that closely related Ficus species produce similar receptive fig odours. Under particular contexts of odours locally present, the receptive fig odours of non-host figs of a Ficus species may become attractive to pollinators of closely related Ficus species. We used the headspace technique to collect in situ receptive fig odours of F. triloba in a series of locations in China. Under controlled conditions, we tested the attraction of fig pollinating wasps from F. hirta and F. triloba to host figs and non-host figs in Y tube experiments.

Results
Receptive fig odours of F. triloba though different from those of F. hirta, were mainly composed of a same set of volatile organic compounds. When given the choice between receptive fig odours and air, the pollinating wasps were only attracted by their host’s odours. However, when given a choice between host and non-host figs the pollinators of F. hirta were equally attracted by the two odours while the pollinators of F. triloba tended to be more attracted by their host’s fig odours.

Conclusions
Receptive fig odours vary geographically within species and the differentiation of receptive fig odours between closely related Ficus species is often incomplete. This allows localised or occasional pollinator sharing following different modalities. Cross stimulation when wasps are exposed simultaneously to odours of host and non-host species may be important. While occasional pollinator sharing may play a marginal role when wasp populations are robust, it may ensure the provisioning of new pollinators from the closest relative of a Ficus species if its pollinators go extinct.