bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does pericapsular nerve group block have limited analgesia at the initial post-operative period? Systematic review and meta-analysis
Authors: Farag Ahmed , Hendi Nada Ibrahim , Diab Rehab Adel 
Published: November 2022

AbstractPerioperative pain management related to hip surgical procedures is challenging. Pericapsular nerve group (PENG) block is a novel technique that is assumed to provide better analgesia in addition to its post-operative motor-sparing effect. In this review, we aim to assess the safety and efficacy of PENG block on pain management in patients undergoing hip surgeries. Fifteen clinical trials with a total of 837 patients were included. Pain scores favored PENG group when compared to FICB group (fascia iliaca compartment block) or analgesics-only group, but the difference could only be detected in the early post-operative period. Afterward, it seems to lose its superiority, and no difference could be detected. In addition, cumulative opioid consumption favored PENG group at 24 h but not at 48 h. Regarding patients’ satisfaction, our analysis showed results favoring PENG group, but there was no difference in time to first opioid or length of hospital stay. The incidence of vomiting was lower in PENG, but there was no difference in the incidence of nausea, pruritis, and dizziness. PENG provides better analgesia and lower opioid consumption in the initial post-operative period. Current evidence is not enough, and further high-quality randomized controlled trials with larger sample sizes are required.
Evaluation of the prevalence of the most common psychiatric disorders in patients with type 2 diabetes mellitus using the patient health questionnaire: results of the cross-sectional “DIA2PSI” study
Authors: Claro Angelo Emilio , Palanza Clelia , Mazza Marianna , Corsello Andrea , Rizzi Alessandro , Tartaglione Linda , de Waure Chiara , Marano Giuseppe , Piciollo Simone , Muti Schuenemann Giovanna Elsa Ute , Rigoni Marta , Muti Paola , Pontecorvi Alfredo , Janiri Luigi , Sani Gabriele , Pitocco Dario 
Published: November 2022

Abstract
Aims
Common Psychiatric Disorders (CPDs) are associated with the development of overweight and obesity, the strongest risk factors for the onset and maintenance of Type 2 Diabetes mellitus (T2D). To the best of our knowledge, this is the first study to assess the prevalence of CPDs in patients with T2D in Italy.

Methods
This is a monocentric cross-sectional study; n = 184 T2D patients were screened for CPDs using the Patient Health Questionnaire (PHQ). Primary outcome was to evaluate the prevalence of CPDs. To assess association between CPDs and risk factors, we have utilized univariable logistic regression models.

Results
64.1% were men, median age was 67 (59–64) and median BMI 27 (25–30) kg/m2. The 42.9% tested positive for one or more mental disorders, 25.6% for depression. Patients with higher BMI (p = 0.04) had an increased likelihood of testing positive to the PHQ. Patients who had implemented lifestyle changes (p < 0.01) and were aware that mental health is linked to body health (p = 0.07) had a reduction in the likelihood of testing positive.

Conclusions
Prevalence of CPDs in T2D patients is higher than in the general population. Since CPDs favor the onset and subsistence of T2D, integrated diabetic-psychiatric therapy is required for improvement or remission of T2D in patients with comorbid CPDs.
Prähospitales Atemwegsmanagement in zwei deutschen Städten
Authors: Reinert Lukas F. , Herdtle Steffen , Hohenstein Christian , Behringer Wilhelm , Arrich Jasmin 
Published: November 2022

Zusammenfassung

Hintergrund und Fragestellung
In der prähospitalen Notfallmedizin ist ein erweitertes Atemwegsmanagement eine wichtige Fähigkeit für Notärzte und Notärztinnen . Sein Erfolg bestimmt die Komplikationen und die Sterblichkeit der Patient(inn)en. Ziel der Studie war es, das prähospitale erweiterte Atemwegsmanagement der bodengebundenen Rettungsdienste in zwei vergleichbaren deutschen Städten zu charakterisieren.

Material und Methoden
Retrospektive Analyse eines prähospitalen Atemwegsmanagementregisters (intubationsregister.de) im Jahr 2018, mit einem Vergleich der Patientenfaktoren, der Intubationssituation, der Charakteristika des Rettungsteams und des Rettungsdiensts in zwei mittelgroßen Städten in Deutschland.

Ergebnisse
Trotz ähnlicher Demografien und vergleichbarer Strukturen der Rettungsdienste fanden sich relevante Unterschiede in der Intubationssituation, dem Ausbildungsgrad der Notärzte und Notärztinnen, der Art der verwendeten Muskelrelaxanzien, der Verfügbarkeit der Videolaryngoskopie, dem Erfolg des ersten Intubationsversuchs und Komplikationen.

Diskussion
Eine strukturierte Erhebung des prähospitalen Atemwegsmanagements und ein Vergleich zwischen den Rettungsdiensten unterschiedlicher Städte können relevante Unterschiede aufzeigen und neue Ansatzpunkte für eine verbesserte Patientenversorgung bieten. Weitere Untersuchungen sind notwendig, um die Ergebnisse zu bestätigen und weitere Fragestellungen anschließen zu können.
A limiting analysis on regularization of singular SDP and its implication to infeasible interior-point algorithms
Authors: Tsuchiya Takashi , Lourenço Bruno F. , Muramatsu Masakazu , Okuno Takayuki 
Published: November 2022

AbstractWe consider primal-dual pairs of semidefinite programs and assume that they are singular, i.e., both primal and dual are either weakly feasible or weakly infeasible. Under such circumstances, strong duality may break down and the primal and dual might have a nonzero duality gap. Nevertheless, there are arbitrary small perturbations to the problem data which would make them strongly feasible thus zeroing the duality gap. In this paper, we conduct an asymptotic analysis of the optimal value as the perturbation for regularization is driven to zero. Specifically, we fix two positive definite matrices, $$I_p$$

I
p

and $$I_d$$

I
d

, say, (typically the identity matrices), and regularize the primal and dual problems by shifting their associated affine space by $$\eta I_p$$

η

I
p

and $$\varepsilon I_d$$

ε

I
d

, respectively, to recover interior feasibility of both problems, where $$\varepsilon $$
ε
and $$\eta $$
η
are positive numbers. Then we analyze the behavior of the optimal value of the regularized problem when the perturbation is reduced to zero keeping the ratio between $$\eta $$
η
and $$\varepsilon $$
ε
constant. A key feature of our analysis is that no further assumptions such as compactness or constraint qualifications are ever made. It will be shown that the optimal value of the perturbed problem converges to a value between the primal and dual optimal values of the original problems. Furthermore, the limiting optimal value changes “monotonically” from the primal optimal value to the dual optimal value as a function of $$\theta $$
θ
, if we parametrize $$(\varepsilon , \eta )$$

(
ε
,
η
)

as $$(\varepsilon , \eta )=t(\cos \theta , \sin \theta )$$

(
ε
,
η
)
=
t
(
cos
θ
,
sin
θ
)

and let $$t\rightarrow 0$$

t
→
0

. Finally, the analysis leads us to the relatively surprising consequence that some representative infeasible interior-point algorithms for SDP generate sequences converging to a number between the primal and dual optimal values, even in the presence of a nonzero duality gap. Though this result is more of theoretical interest at this point, it might be of some value in the development of infeasible interior-point algorithms that can handle singular problems.
A systematic review and meta-analysis of paraoxonase-1 activity in asthma
Authors: Bassu Stefania , Mangoni Arduino A. , Argiolas Dario , Carru Ciriaco , Pirina Pietro , Fois Alessandro G. , Zinellu Angelo 
Published: November 2022

AbstractHuman serum paraoxonase-1 (PON-1) is a critical antioxidant defence system against lipid oxidation. Decreased PON-1 activity has been associated with systemic oxidative stress in several disease states. We conducted a systematic review and meta-analysis of plasma/serum concentrations of PON-1 in asthma, a chronic inflammatory airway disease. The electronic databases PubMed, Web of Science, Scopus and Google Scholar were searched from inception to February 2022. In total, 8 studies in 355 asthmatic patients and 289 healthy controls were included in the meta-analysis. Serum PON-1 concentrations were significantly lower in asthmatic patients (SMD = −1.58, 95% CI −2.53 to −0.63; p = 0.001). The pooled SMD values were not substantially altered in sensitivity analysis. There was no publication bias. There were non-significant differences in PON-1 concentrations in patients with severe vs. mild-to-moderate asthma (SMD =  − 0.39, 95% CI − 1.00 to 0.22, p = 0.21). Our meta-analysis has shown that serum PON-1 concentrations are significantly lower in patients with asthma, suggesting the presence of an impaired antioxidant defense in this group.
Serum levels of angiotensin-converting enzyme 2 in children with Kawasaki disease
Authors: Gan Yi , Feng Yawei , Zhou Xiaoqin , Li Heng , Wang Guirong , Aini Maidina , Shu Junhua , Tu Danna 
Published: November 2022

AbstractKawasaki disease (KD) has replaced rheumatic fever as the main cause of acquired heart disease in Japanese, American, and Chinese children. Polymorphisms in angiotensin-converting enzyme may be associated with susceptibility to KD, but the association of angiotensin-converting enzyme 2 (ACE2) with vascular endothelial injury in KD and the possibility for prognosis of vascular injury in KD by evaluating changes in serum ACE2 have not yet been assessed. Thus, this study aimed to investigate ACE2 levels in patients with KD to further explore the relationship between ACE2 and vascular injury in KD. Blood samples were collected from 49 children with KD before intravenous immunoglobulin treatment and 28 healthy children in the same period as the control group. Clinical data were collected from the patients and serum ACE2 levels of all participants were measured using an enzyme-linked immunosorbent assay. Serum ACE2 levels were significantly higher in the KD group than in the control group, and were negatively correlated with platelet levels in patients with KD. Serum ACE2 levels are related to the pathogenesis of KD and may be used as a potential serum marker for KD diagnosis.
Modeling ecosystems of reference frameworks for assurance: a case on privacy impact assessment regulation and guidelines
Authors: Ruiz Alejandra , Martin Yod-Samuel , Martinez Jabier , Quintans Jacobo , Mockly Guillaume , Gyrard Amelie , Crepax Tommaso 
Published: November 2022

AbstractTo assure certain critical quality properties (e.g., safety, security, or privacy), supervisory authorities and industrial associations provide reference frameworks such as standards or guidelines that in some cases are enforced (e.g., regulations). Given the pace at which both technical advancements and risks appear, there is an increase in the number of reference frameworks. As several frameworks might apply for same systems, certain overlaps appear (e.g., regulations for different countries where the system will operate, or generic standards in conjunction with more concrete standards for a given industrial sector or system type). We propose the use of modelling for alleviating the complexity of these reference frameworks ecosystems, and we provide a tool-supported method to create them for the benefit of different stakeholders. The case study is based on privacy data protection, and more concretely on privacy impact assessment processes. The European GDPR regulates the movement and processing of personal data, and, contrary to available software engineering privacy guidelines, articles in legal texts are usually difficult to translate to the underlying processes, artefacts and roles that they refer to. To facilitate the mutual comprehension of legal experts and engineers, in this work we investigate how mappings can be created between these two domains of expertise. Notably, we rely on modelling as a central point. We modelled the legal requirements of the GDPR on data protection impact assessments, and then, we selected the ISO/IEC 29134, a mainstream engineering guideline for privacy impact assessment, and, taking a concrete sector as example, the EU Smart Grid Data Protection Impact Assessment template. The OpenCert tool was used for providing technical support to both the modelling and the creation of the mapping models in a systematic way. We provide a qualitative evaluation from legal experts and privacy engineering practitioners to report on the benefits and limitations of this approach.
The calcium-antagonist activity of the material released by olive pollen (PMR), tested on Ca2+-cytosolic of PE/CA-PJ15 cells
Authors: Vitali Alberto , Del Pino Alberto Marco , Regni Luca , Costanzi Eva , Bravi Elisabetta , Marconi Ombretta , Proietti Primo , Palmerini Carlo Alberto 
Published: November 2022

AbstractInhalation of olive pollen (Olea europaea L.) is one of the main causes of allergy in Mediterranean countries and some areas of North America. The response to allergens consists in the production of inflammatory cytokines which is mediated by the deregulation of Ca2+ signals. In this study, the biological activity of the material released in olive pollen hydration (PMR) was tested on Ca2+ cytosolic of PE/CA-PJ15 cells (PJ-15). Ca2+ cytosolic was determined by fluorometric assay with the cell line PE/CA-PJ15 (PJ-15) labeled with the fluorescent probe FURA 2 AM. The material released in olive pollen hydration (PMR) was analyzed by HPLC for the determination of phenolic acids. PMR was subjected to fractionation by gel filtration, and the fractions with Ca2+-chelating activity were tested with SDS-PAGE and the single bands characterized by proteomic analysis. PMR showed high Ca2+-chelating activity and is able of blocking the increase Ca2+-cytosolic produced by thapsigargin (TG). PMR then restored Ca2+ homeostasis in PJ-15 cells deregulated by the endoplasmic reticulum Ca2+-ATPases inhibitor. It is therefore possible that PMR can antagonize the effects of allergens on Ca2+ cytosolic. The analytical characterization of the material released by the pollen highlighted in the pollen allergen Ole e 3 and in the p-coumaric acid the possible culprits of the Ca2+-antagonist activity of PMR. Furthermore, the sequence of Ole e 3 could provide information for the possible construction of a synthetic peptide to be used in an allergy-targeted Ca2+-antagonist therapy.
On the SCD semismooth* Newton method for generalized equations with application to a class of static contact problems with Coulomb friction
Authors: Gfrerer Helmut , Mandlmayr Michael , Outrata Jiří V. , Valdman Jan 
Published: November 2022

AbstractIn the paper, a variant of the semismooth$$^{*}$$

∗

Newton method is developed for the numerical solution of generalized equations, in which the multi-valued part is a so-called SCD (subspace containing derivative) mapping. Under a rather mild regularity requirement, the method exhibits (locally) superlinear convergence behavior. From the main conceptual algorithm, two implementable variants are derived whose efficiency is tested via a generalized equation modeling a discretized static contact problem with Coulomb friction.
Properties and applications of the Apéry set of good semigroups in $$\mathbb {N}^d$$
Authors: Guerrieri L. , Maugeri N. , Micale V. 
Published: November 2022

AbstractIn this article, we discuss some applications of the construction of the Apéry set of a good semigroup in $$\mathbb {N}^d$$

N

d

given in (Commun Algebra 49(10):4136–4158, 2021). In particular, we study the duality of a symmetric and almost symmetric good semigroup, the Apéry set of non-local good semigroups and the Apéry set of value semigroups of plane curves.
Sustainable Bio-Based Materials from Minimally Processed Red Seaweeds: Effect of Composition and Cell Wall Structure
Authors: Cebrián-Lloret Vera , Martínez-Abad Antonio , López-Rubio Amparo , Martínez-Sanz Marta 
Published: November 2022

AbstractThis study reports on the use of whole seaweed biomass to obtain bio-based films for food packaging applications. Specifically, four different species of agarophytes (Gelidium corneum, Gracilaria chilensis, Gracilaria tenuistipitata and Gracilariopsis longissima) were minimally processed by melt blending and compression molding, and the effect of their composition and cell wall structure on the final performance of the films was investigated. The seaweed biomass was mainly composed of carbohydrates (35–50%), but significant amounts of proteins and ashes were also detected. Temperature-resolved SAXS experiments and microscopy analyses evidenced that a higher temperature of 130 ℃ is required to promote the release of agar from the tougher cell walls from G. corneum and G. tenuistipitata. The higher cellulose content of G. corneum (ca. 15%) resulted in films with higher mechanical resistance and water vapor barrier capacity, while the higher agar content of G. chilensis improved the elongation capacity of the films. The results from this work evidence the potential of red seaweed biomass to generate food packaging materials in a cost-effective and environmentally friendly way.
How to charge while driving: scheduling point-to-point deliveries of an electric vehicle under overhead wiring
Authors: Boysen Nils , Briskorn Dirk , Schwerdfeger Stefan 
Published: November 2022

AbstractElectrifying road-based long-haul transportation is an intricate task. Given the current state of battery technology, either the driving ranges of electric commercial vehicles (ECVs) are too short or high-capacity batteries are costly and so heavy that payloads are limited. An old, yet recently revitalized, charging infrastructure currently evaluated on multiple test tracks around the globe alternatively suggests charging of electric trucks while driving. Analogously to trams, trolley buses, or trains, ECVs are powered by an electric motor connected to overhead wires via a movable contact arm and supported by a battery or an extra conventional drive, which steps in on non-electrified road segments. This paper is dedicated to the routing of a single ECV executing full-truckload point-to-point deliveries along a highway main line where charge-while-drive infrastructure is fixedly installed along some but not all parts of the road. We formulate the resulting optimization problem, investigate computational complexity, and provide suitable solution procedures based on decomposition. Once all this is available, we explore the induction effect of charge-while-drive technology, i.e., the amount of charging detours required to gather enough energy for the next job. Our results show that the induction effect can be considerable and may lead to substantial extra traffic compared to conventional charge-while-park technology.
Thermal properties and decomposition mechanism of disubstituted fused 1,2,4-triazoles considered as potential anticancer and antibacterial agents
Authors: Worzakowska Marta , Sztanke Małgorzata , Sztanke Krzysztof 
Published: November 2022

AbstractThermal resistance is a very important parameter when assessing the therapeutic usefulness of potential pharmaceutics. Therefore, the thermal behaviour and the decomposition mechanism in the atmosphere of helium and synthetic air of disubstituted fused 1,2,4-triazoles—which may be potential anticancer and antibacterial agents—were studied with a use of simultaneous thermal analysis: thermogravimetry/differential scanning calorimetry (TG/DTG/DSC) coupled online with Fourier transform infrared spectroscopy. It was confirmed that the thermal stability of the tested compounds is directly depended on their structure and thus on the number of chlorine atoms as substituents. The pyrolysis process of disubstituted fused 1,2,4-triazoles in inert conditions runs in two main, non-well-separated stages connected with the emission of NH3, HCN, acetonitrile, aromatics with an OH group, aromatics with a NH2 groups, H2O, CO2 and alkene fragments. However, the thermal stability of those compounds in synthetic air atmosphere is comparable or lower than their thermal stability in helium atmosphere. The decomposition of the tested compounds runs through at least three main stages, resulting in the emission of the same type of volatiles as in inert conditions plus the additional emission of CO and some carbonyl fragments for compounds with no or one chlorine atom as a substituent. The results indicate a simultaneous cleavage of C–N, N–N and C–O bonds during heating of the tested disubstituted fused 1,2,4-triazoles in inert conditions and additional combustion process of pre-formed residues in oxidative conditions.
Inter-municipal vs. Inter-governmental Cooperation: Their Impact on International Aid
Authors: Zambrano-Gutiérrez Julio C. , Avellaneda Claudia N. 
Published: November 2022

AbstractThis study combines the type of partners and the number of partnerships’ purposes to assess municipal partnerships’ effectiveness in bringing international aid. First, the study test whether inter-municipal cooperation (homogenous partners) is more effective than inter-governmental cooperation (heterogeneous partners) in increasing international aid at the local level. Second, the study tests whether partnerships with the sole purpose of raising international aid (single purpose) are more effective than partnerships with additional purposes (multiple purposes). Using panel data with 2,431 municipal-year observations, results confirm that inter-governmental partnerships with multiple purposes are the most effective partnership to increase international aid.
Experience Goods, Umbrella Branding, and Reputation
Authors: Niinimäki J.-P. 
Published: November 2022

AbstractThis paper examines umbrella brands—brand stretching or brand extension—in a model of experience goods and an infinite number of periods. A monopoly firm has short-run incentives to compromise on product quality so as to save costs, as buyers can observe quality only ex post. The paper shows that the overlapping structure of product launching strengthens umbrella branding, mitigates moral hazard, and makes easier the building of a good reputation and its maintenance. The overlapping structure generates switching costs between strategies.