bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tuning the Thermoelectric Properties of Boron‐Doped Silicon Nanowires Integrated into a Micro‐Harvester
Authors: Sojo‐Gordillo Jose M. , Estrada‐Wiese Denise , Duque‐Sierra Carolina , Gadea‐Díez Gerard , Salleras Marc , Fonseca Luis , Morata Alex , Tarancón Albert 
Published: May 2022

AbstractSemiconductor nanowires demonstrate outstanding properties within a wide range of application fields, including energy harvesting. Consequently, increasing attention has been focused on silicon nanowires for thermoelectric power generation after their successful implementation in miniaturized devices. In this work, the effect of tuning the p‐type doping level in silicon nanowires is studied in thermoelectric micro‐generators. In situ heavily boron‐doped silicon nanowires are grown by the vapor‐liquid‐solid mechanism in a chemical vapor deposition reactor. Variable quantities of dopant gas—diborane or B2H6—are used to control the doping level and study the direct influence on the thermoelectric properties of the nanowires. The relationship between dopant partial pressure and resulting carrier concentration is evaluated, and all thermoelectric properties are studied as a function of each doping level. A maximum power factor of 2.0 ± 0.2 mW mK−2 is found for a carrier concentration of 2.5 × 1019 cm−3, corresponding to a figure of merit of zT = 0.04 at near room temperature. Optimized nanowires are included in a micro‐machined thermoelectric generator, yielding an open circuit voltage of 4.5 mV and maximum power output of 1.08 μW cm−2 upon hot surfaces at 250 °C.
Progress on 3D‐Printed Metal‐Organic Frameworks with Hierarchical Structures
Authors: Lieu Wei Ying , Fang Daliang , Tay Kay Jin , Li Xue Liang , Chu Wei Che , Ang Yee Sin , Li Dong‐Sheng , Ang Lay‐Kee , Wang Ye , Yang Hui Ying 
Published: May 2022

AbstractMetal‐organic frameworks (MOFs) have attracted considerable attention in numerous applications due to their large surface areas, tunable pore size, and chemical versatility. However, the performance of most MOFs and their related derivatives in applications are still hindered due to their unoptimized form. Hierarchical nano‐micromacropore MOF structure constructed by 3D printing has been shown to guide working species transportation routes, accelerates ion transportation, and increases the accessible area of MOF, thus leading to improved kinetics and enhanced application performances. Nevertheless, there is a lack of a review on 3D‐printed MOFs and their applications that summarizes and promotes this field's progress. This review first introduces the progress of preparing and embedding MOF into structures via 1) MOF coating processes, 2) in situ growth of MOFs, and 3) using presynthesized MOFs to tune the nano‐ and microstructure of MOF. Subsequently, based on various 3D printing technologies, the principles behind various feedstock material preparation and their related printing processes are discussed with respect to the macrostructure. Thereafter, the advances and recent progress of various devices by 3D‐printed MOFs are summarized with detailed analyses and discussion. Finally, an outlook in this promising field is proposed to provide a progression route for 3D‐printed MOFs.
Solid‐State Iontronic Devices: Mechanisms and Applications
Authors: Li Tianming , Xiao Kai 
Published: May 2022

AbstractIontronics is a newly emerging interdisciplinary concept that studies the science and technology of electronic‐ionic coupled properties/functions, endowing the devices with new functions and properties by coupling the advantages of electrons and ions. Solid‐state iontronics, one of the most important branches of iontronics, refers to the iontronic devices that work in solid‐state environments, which attracts particular attention due to its overwhelming advantages, for example, the enhanced thermal/mechanical/electrochemical stability. Herein, the interesting ion‐involved working principles of various solid‐state iontronic devices, including energy storage, electromechanics, electrochromism, electroluminescence, and conductance switching, are reviewed. Meanwhile, the perspectives on developing multifunctional integrated iontronic devices and molecular iontronic devices are also addressed, aiming to meet the growing demands for next‐generation intellectual products. We believe that this review can encourage further exploration in this exciting research field.
High Energy Storage Performance in Ba0.85Ca0.15Zr0.1Ti0.9O3‐ZnO Hybrid Perovskite Solid Solution Thin Films
Authors: Zhang Xiaoyu , Jiao Peijie , Cheng Hao , Xiong Ke , Yang Jiangfeng , Chen Lan , Zhou Jinfeng , Zhu Zimeng , Zhang Ji , Luo Jin , Wang Jing , Yang Yurong , Zhang Shan‐Tao , Wu D. , Liu Jun‐Ming 
Published: May 2022

AbstractRelaxor property plays a key role in determining energy storage performance of dielectric capacitor. The usual method to improve relaxor property is to form substitutional solid solution. Here an unusually substitutional and interstitial hybrid perovskite solid solution 0.8(Ba0.85Ca0.15Zr0.1Ti0.9O3)‐0.2ZnO (BCZT:Zn) is designed, where one Zn2+ occupies B‐site and two Zn2+ share one A‐site of perovskite structure, and fabricated its epitaxial thin films. Compared to BCZT films, BCZT:Zn films have increased c/a ratio which leads to enhanced maximum polarization Pmax, wide band gap therefore high electrical breakdown strength EBDS, and enhanced relaxor degree thus suppressed remanent polarization Pr. As the results, dramatically improve energy storage property with the recoverable energy storage density Wrec of 75.9 J cm−3 and the energy storage efficiency η of 76.7% are obtained in BCZT:Zn films. This work not only provides a high performance relaxor ferroelectric material, but also impacts some new thinking to optimize die/ferro/piezoelectric properties by forming hybrid solid solutions.
How soil conservation influences agricultural land prices
Authors: Telles Tiago Santos , Maia Alexandre Gori , Reydon Bastiaan Philip 
Published: May 2022

AbstractConservation practices preserve soil quality and may also increase the value of agricultural land. The economic benefits of conservation practices include increased agricultural yields, decreased risk of production losses from weather events, decreased number of farming operations, simplification of farm management, and decreased production costs. We analyze the links between soil conservation practices and the value of agricultural lands. The soil conservation practices considered in this study include no‐tillage, crop rotation, contour farming, and the use of agricultural terraces. We use municipal data on annual crops in the state of Paraná from the 2006 Brazilian Census of Agriculture. Results show that the average value of lands under conventional tillage is between 10 and 22% lower than lands under no‐tillage, ceteris paribus. The economic benefits of adopting no‐tillage can be maximized when performed in conjunction with other conservation practices, including crop rotation, contour farming, and agricultural terracing. Finally, we discuss the critical effect of soil conservation and conservation agriculture on land prices and how these factors may affect farmers’ decision‐making.
Towards Control and Oversight of SARS‐CoV‐2 Diagnosis and Monitoring through Multiplexed Quantitative Electroanalytical Immune Response Biosensors
Authors: Torrente‐Rodríguez Rebeca M. , Montero‐Calle Ana , San Bartolomé Clara , Cano Olga , Vázquez Mónica , Iglesias‐Caballero María , Corral‐Lugo Andrés , McConnell Michael J. , Pascal Mariona , Mas Vicente , Pingarrón José M. , Barderas Rodrigo , Campuzano Susana 
Published: May 2022

AbstractThe development of versatile and sensitive biotools to quantify specific SARS‐CoV‐2 immunoglobulins in SARS‐CoV‐2 infected and non‐infected individuals, built on the surface of magnetic microbeads functionalized with nucleocapsid (N) and in‐house expressed recombinant spike (S) proteins is reported. Amperometric interrogation of captured N‐ and S‐specific circulating total or individual immunoglobulin (Ig) isotypes (IgG, IgM, and IgA), subsequently labelled with HRP‐conjugated secondary antibodies, was performed at disposable single or multiplexed (8×) screen‐printed electrodes using the HQ/HRP/H2O2 system. The obtained results using N and in‐house expressed S ectodomains of five SARS‐CoV‐2 variants of concern (including the latest Delta and Omicron) allow identification of vulnerable populations from those with natural or acquired immunity, monitoring of infection, evaluation of vaccine efficiency, and even identification of the variant responsible for the infection.
Genomic Risk Score for Advanced Osteoarthritis in Older Adults
Authors: Lacaze Paul , Wang Yuanyuan , Polekhina Galina , Bakshi Andrew , Riaz Moeen , Owen Alice , Franks Angus , Abidi Jawad , Tiller Jane , McNeil John , Cicuttini Flavia 
Published: May 2022

ObjectivePrevention of osteoarthritis (OA) remains important, as there are no disease‐modifying treatments. A personalized approach has the potential to better target prevention strategies. In the present study, we used recently identified genetic risk variants from genome‐wide association analysis for advanced OA to calculate polygenic risk scores (PRS) for knee and hip OA and assessed PRS performance in an independent population of older community‐dwelling adults.MethodsPRS were calculated in 12,093 individuals of European genetic descent ages ≥70 years who were enrolled in the Aspirin in Reducing Events in the Elderly trial. The outcome measure was knee and hip replacement (hospitalizations during the trial and self‐reported joint replacements before enrollment). PRS were considered as continuous (per SD) and categorical (low risk [0–20%], medium risk [21–80%], high risk [81–100%]) variables. Logistic regression was used to examine associations between PRS and risk of joint replacement, adjusted for age, sex, body mass index, and socioeconomic status.ResultsAmong the participants, 1,422 (11.8%) had knee replacements and 1,297 (10.7%) had hip replacements. PRS (per SD) were associated with a risk of knee replacement (odds ratio [OR] 1.13 [95% confidence interval (95% CI) 1.07–1.20]) and hip replacement (OR 1.23 [95% CI 1.16–1.30]). Participants with high PRS had an increased risk of knee replacement (OR 1.44 [95% CI 1.20–1.73]) and hip replacement (OR 1.88 [95% CI 1.56–2.26]), compared to those with low PRS. Associations were stronger for PRS and hip replacement risk in women than in men. Associations were similar in sensitivity analyses that examined joint replacements before and during the trial separately.ConclusionPRS have the potential to improve prevention of severe knee and hip OA by providing a personalized approach and identifying individuals who may benefit from early intervention.
Plasmablast‐like Phenotype Among Antigen‐Experienced CXCR5–CD19low B Cells in Systemic Lupus Erythematosus
Authors: Szelinski Franziska , Stefanski Ana Luisa , Schrezenmeier Eva , Rincon‐Arevalo Hector , Wiedemann Annika , Reiter Karin , Ritter Jacob , Lettau Marie , Dang Van Duc , Fuchs Sebastian , Frei Andreas P. , Alexander Tobias , Lino Andreia C. , Dörner Thomas 
Published: May 2022

ObjectiveAltered composition of the B cell compartment in the pathogenesis of systemic lupus erythematosus (SLE) is characterized by expanded plasmablast and IgD–CD27– double‐negative B cell populations. Previous studies showed that double‐negative B cells represent a heterogeneous subset, and further characterization is needed.MethodsWe analyzed 2 independent cohorts of healthy donors and SLE patients, using a combined approach of flow cytometry (for 16 healthy donors and 28 SLE patients) and mass cytometry (for 18 healthy donors and 24 SLE patients) and targeted RNA‐Seq analysis. To compare B cell subset formation during the acute immune response versus that during autoimmune disease, we investigated healthy donors at various time points after receipt of the BNT162b2 messenger RNA COVID‐19 vaccine and patients with acute SARS–CoV‐2 infection, using flow cytometry.ResultsWe found that IgD–CD27+ switched and atypical IgD–CD27– memory B cells, the levels of which were increased in SLE patients, represented heterogeneous populations composed of 3 different subsets each. CXCR5+CD19intermediate, CXCR5–CD19high, and CXCR5–CD19low populations were found in the switched memory and double‐negative compartments, suggesting the relatedness of IgD–CD27+ and IgD–CD27– B cells. We characterized a hitherto unknown and antigen‐experienced CXCR5–CD19low subset that was enhanced in SLE patients, had a plasmablast phenotype with diminished B cell receptor responsiveness, and expressed CD38, CD95, CD71, PRDM1, XBP1, and IRF4. Levels of CXCR5–CD19low subsets were increased and correlated with plasmablast frequencies in SLE patients and in healthy donors who received BNT162b2, suggesting their interrelationship and contribution to plasmacytosis. The detection of CXCR5–CD19low B cells among both CD27+ and CD27– populations calls into question the role of CD27 as a reliable marker of B cell differentiation.ConclusionOur data suggest that CXCR5–CD19low B cells are precursors of plasmablasts. Thus, cotargeting this subset may have therapeutic value in SLE.
Exponential ultimate boundedness and stability of stochastic differential equations with impulese
Authors: Huang Fang , Li Jianli 
Published: May 2022

AbstractThe paper mainly studies globally pth moment exponentially ultimate boundedness and pth moment exponential stability of impulsive stochastic functional differential equations. By using the Lyapunov direct method of Razumikhin‐type condition and the principle of comparison, some sufficient conditions for globally pth moment exponentially ultimate boundedness and globally pth moment exponential stability are presented. Theorems require the linear coefficients of the upper bound of Lyapunov differential operators are time‐varying functions; this generalizes the previous results. When the time delay is not considered in the system, a unified criterion is given to achieve boundedness and stability when the system is disturbed by stabilizing impulse and destabilizing impulse. It shows that the stochastic differential equation may be unbounded or unstable, and it can be bounded or stable by adding appropriate impulsive perturbation. Finally, we use two examples to illustrate the validity of our results.
Model‐based periodic event‐triggered stabilization for continuous‐time stochastic nonlinear systems
Authors: Yu Peilong , Kang Yu , Zhang Niankun 
Published: May 2022

AbstractIn this paper, we investigate a model‐based periodic event‐triggered control framework for continuous‐time stochastic nonlinear systems. In this framework, an auxiliary approximate discrete‐time model of stochastic nonlinear systems is constructed in the controller module, which is utilized not only to design a discrete‐time controller but also as a state predictor within trigger intervals. This discrete controller design approach, the strategy of state prediction, and the periodic detection strategy for the trigger rule not only provide a manner of more direct and easier implementation on the digital platform but also effectively reduce the communication load while a satisfactory control performance is maintained. Additionally, the mean‐square exponentially stabilization for continuous‐time stochastic nonlinear systems is achieved, in which a guideline for determining the maximum admissible sampling period is provided and the periodic event trigger rule is designed. The final numerical simulation also supports the effectiveness of our proposed framework.
Event‐triggered finite‐time dynamic output feedback control for switched affine systems with asynchronous switching
Authors: Chen Yunjun , Mao Xin , Zong Guangdeng , Yang Dong , Shi Kaibo 
Published: May 2022

AbstractThis paper investigates the event‐triggered finite‐time dynamic output feedback control for switched affine systems (SASs) with asynchronous switching. A key point of the study is to set up a dynamic output feedback switched affine controller together with an event‐triggered mechanism (ETM). By using an average dwell time (ADT) approach and resorting to a controller‐mode‐dependent Lyapunov functional, the finite‐time stability (FTS) performance is achieve for the closed‐loop SASs. The system dynamics under the proposed ETM are fully discussed during the synchronous and asynchronous switching intervals. The existence of the lower bound on interevent intervals is discussed emphatically, which excludes the occurrence of Zeno behavior. Finally, an application example of the DC‐DC converter is given to show effectiveness of the acquired control algorithm.
Preview control of polytopic time‐varying systems subject to actuator saturation
Authors: Li Li , Lu Yanrong , Meng Xiaohua 
Published: May 2022

AbstractIn this study, a novel method is proposed to track a previewable reference signal in the polytopic time‐varying system with input saturation. Firstly, an augmented model containing future information is constructed using a new formal variable. This leads to the tracking control problem of polytopic time‐varying system with input saturation is transformed into a stability problem of augmented error system. Next, the state and static output feedback preview controls are introduced, and the corresponding controller gains are produced by the proposed conditions. Two examples are presented to validate the effectiveness of the proposed preview controller.
On the simultaneous stabilization of stochastic nonlinear systems
Authors: Himmi Hanane , Oumoun Mohamed 
Published: May 2022

SummaryIn this paper, the problem of simultaneous stabilization in probability by state feedback is investigated for a class of stochastic nonlinear systems whose drift and diffusion terms are dependent on the control and for which classical methods are not applicable. Under the assumption that a collection of stochastic control Lyapunov functions (SCLFs) is known and based on the generalized stochastic Lyapunov theorem, we derive sufficient conditions for the simultaneous stabilization in probability by a continuous state feedback controller that we explicitly compute. We also derive a necessary condition when the system coefficients satisfy some regularity conditions. This work generalizes previous results on the simultaneous stabilization of stochastic nonlinear systems. The obtained results are illustrated by a numerical example.
Sound‐guided assessment and localization of pulmonary air leak
Authors: Pinezich Meghan R. , Mir Mohammad , Reimer Jonathan A. , Kaslow Sarah R. , Chen Jiawen , Guenthart Brandon A. , Bacchetta Matthew , O'Neill John D. , Vunjak‐Novakovic Gordana , Kim Jinho 
Published: May 2022

AbstractPulmonary air leak is the most common complication of lung surgery, with air leaks that persist longer than 5 days representing a major source of post‐surgery morbidity. Clinical management of air leaks is challenging due to limited methods to precisely locate and assess leaks. Here, we present a sound‐guided methodology that enables rapid quantitative assessment and precise localization of air leaks by analyzing the distinct sounds generated as the air escapes through defective lung tissue. Air leaks often present after lung surgery due to loss of tissue integrity at or near a staple line. Accordingly, we investigated air leak sounds from a focal pleural defect in a rat model and from a staple line failure in a clinically relevant swine model to demonstrate the high sensitivity and translational potential of this approach. In rat and swine models of free‐flowing air leak under positive pressure ventilation with intrapleural microphone 1 cm from the lung surface, we identified that: (a) pulmonary air leaks generate sounds that contain distinct harmonic series, (b) acoustic characteristics of air leak sounds can be used to classify leak severity, and (c) precise location of the air leak can be determined with high resolution (within 1 cm) by mapping the sound loudness level across the lung surface. Our findings suggest that sound‐guided assessment and localization of pulmonary air leaks could serve as a diagnostic tool to inform air leak detection and treatment strategies during video‐assisted thoracoscopic surgery (VATS) or thoracotomy procedures.
NTRK fusion positive colorectal cancer is a unique subset of CRC with high TMB and microsatellite instability
Authors: Wang Hui , Li Zhi‐Wei , Ou Qiuxiang , Wu Xue , Nagasaka Misako , Shao Yang , Ou Sai‐Hong Ignatius , Yang Yu 
Published: May 2022

AbstractTRK fusions are rare but targetable mutations which occur across a wide variety of cancer types. We report the prevalence of approximately 0.7% for NTRK‐positive colorectal cancer (CRC) by genetically profiling 2519 colonic and rectal tumors. The aberrations of APC and TP53 frequently co‐occurred with NTRK gene fusions, whereas RAS/BRAF oncogenic alterations and NTRK fusions were almost always mutually exclusive. NTRK‐driven colorectal cancer patients demonstrated increased TMB (median = 53 mut/MB, 95% CI: 36.8–68.0 mut/MB), high microsatellite instability, and an enrichment for POLE/POLD1 mutations when compared to molecularly unstratified colorectal cancer population. These data shed light on possible future approach of multimodality treatment regimen including TRK‐targeted therapy and immune checkpoint inhibitor therapy in NTRK‐positive CRCs.
Locoregional recurrence after nephrectomy for localized renal cell carcinoma: Feasibility and outcomes of different treatment modalities
Authors: Liu Yang , Zhang Xinyue , Ma Huali , Tian Li , Mai Lixin , Long Wen , Zhang Zhiling , Han Hui , Zhou Fangjian , Dong Pei , He Liru 
Published: May 2022

AbstractBackgroundLocoregional recurrence after nephrectomy for localized renal cell carcinoma (RCC) is rare with diverse manifestations. The selection criteria and efficacy of different treatments are unanswered. The objective was to compare different treatment modalities and present data on stereotactic body radiotherapy (SBRT) for recurrent RCC.Materials and MethodsPatients with locoregional recurrence after nephrectomy without distant metastasis were identified from institutional big data intelligence platform between 2001 and 2020. Patients receiving local therapy (surgery or SBRT) or systemic therapy alone (targeted therapy or PD‐1 inhibitors) were divided into two groups. Progression‐free survival (PFS) and overall survival (OS) were analyzed using Kaplan–Meier method, Cox regression model. Patients were matched with propensity score matching.ResultsAmong 106 patients, 33 (31.1%) received systemic therapy alone and 73 (68.9%) received local therapy. Local therapy was surgery in 34 patients (32.1%) and SBRT in 39 (36.8%) patients. Patients treated with systemic therapy alone had more non‐clear cell type (p = 0.044), more advanced T stage (p = 0.006), higher number (p = 0.043) but smaller size of lesions (p = 0.042). Patients receiving local therapy had significantly longer PFS than systemic therapy (19.7 vs. 7.5 months, p = 0.001). After matching, the PFS in the local therapy group remained higher (23.9 vs. 7.5 months, p = 0.001). The 2‐year OS of the local therapy group and systemic therapy group was 91.6% and 71.8%, respectively (p = 0.084). Local therapy was associated with better PFS (HR 0.37; p = 0.0003) and OS (HR 0.23; p = 0.002) in multivariate analysis. Grade 2 or higher toxicities related to local therapy occurred in nine patients.ConclusionsLocal therapy could delay disease progression compared with systemic therapy alone. SBRT is safe and effective for locally recurrent RCC.