bluuebunny/crossref_metadata_2025_split huggingface dataset:
An atlas of the developing Tribolium castaneum brain reveals conservation in anatomy and divergence in timing to Drosophila melanogaster
Authors: Farnworth Max S. , Bucher Gregor , Hartenstein Volker 
Published: May 2022

AbstractInsect brains are formed by conserved sets of neural lineages whose fibers form cohesive bundles with characteristic projection patterns. Within the brain neuropil, these bundles establish a system of fascicles constituting the macrocircuitry of the brain. The overall architecture of the neuropils and the macrocircuitry appear to be conserved. However, variation is observed, for example, in size, shape, and timing of development. Unfortunately, the developmental and genetic basis of this variation is poorly understood, although the rise of new genetically tractable model organisms such as the red flour beetle Tribolium castaneum allows the possibility to gain mechanistic insights. To facilitate such work, we present an atlas of the developing brain of T. castaneum, covering the first larval instar, the prepupal stage, and the adult, by combining wholemount immunohistochemical labeling of fiber bundles (acetylated tubulin) and neuropils (synapsin) with digital 3D reconstruction using the TrakEM2 software package. Upon comparing this anatomical dataset with the published work in Drosophila melanogaster, we confirm an overall high degree of conservation. Fiber tracts and neuropil fascicles, which can be visualized by global neuronal antibodies like antiacetylated tubulin in all invertebrate brains, create a rich anatomical framework to which individual neurons or other regions of interest can be referred to. The framework of a largely conserved pattern allowed us to describe differences between the two species with respect to parameters such as timing of neuron proliferation and maturation. These features likely reflect adaptive changes in developmental timing that govern the change from larval to adult brain.
FSOA‐DNFNet: Incremental indexing and image classification using hybrid optimization‐based deep neuro Fuzzy network
Authors: Nadendla Hanumantha Rao , Srikrishna Atluri , Rao Kancherla Gangadhara 
Published: May 2022

AbstractThe rapid evolution and tremendous growth of internet has provided massive growth of unstructured data that leads to a complexity while retrieving dynamic data effectively. The rapid growth in data volume has imposed many challenging constraints, such as necessity to retrieve data completely even if newly arrived samples are occurred and storing of huge volume of data. This has paved a way for concentrating more on incremental learning that functions on information streams. To speed up retrieval, clustering methods and indexes are utilized and periodic updating of clusters is very substantial because of dynamic nature of databases. Moreover, the standard of clustering techniques purely based on data representation techniques, in which traditional methods faced problems like dimensionality explosion and sparsity. To address such limitations, an effectual strategy is developed for incremental indexing and image classification using proposed Feedback Social Optimization Algorithm (FSOA). The image classification is effectively carried out using Deep neuro fuzzy optimizer and it is trained by employing the proposed FSOA and newly FSOA is derived by the integration of Feedback Artificial Tree (FAT) Algorithm and Social Optimization Algorithm (SOA). Moreover, the proposed FSOA has achieved the maximum clustering accuracy of 93.382, the maximum testing accuracy of 94.4, the maximum sensitivity of 91.892, and the maximum specificity of 96.058.
Activation‐Induced Surface Modulation of Biowaste‐Derived Hierarchical Porous Carbon for Supercapacitors
Authors: Sharma Pratigya , Singh Deobrat , Minakshi Manickam , Quadsia Saleha , Ahuja Rajeev 
Published: May 2022

AbstractWheat straw‐derived carbon from the Wheatbelt region in Western Australia was subjected to chemical activation in an electrolyte containing either acid or base treatment. The findings showed an increase in electron/hole mobility towards the interfaces due to the presence of different surface functional groups such as C−SOx−C and S=C in the carbon framework for acid activation. Likewise, the galvanostatic capacitance measured at a current density of 2 mA cm−2 in a three‐electrode configuration for acid‐activated wheat straw exhibited 162 F g−1, while that for base‐activated wheat straw exhibited 106 F g−1. An increase of 34.5 % more capacitance was achieved for acid‐treated wheat straw. This improvement is attributed to the synergistic effects between surface functional groups and electrolyte ions, as well as the electronic structure of the porous electrode.
Environmental sustainability orientation and corporate social responsibility influence on environmental performance of small and medium enterprises: The mediating effect of green capability
Authors: Rehman Shafique Ur , Bresciani Stefano , Yahiaoui Dorra , Giacosa Elisa 
Published: May 2022

AbstractDespite the increasing research to determine the influence of environmental sustainability orientation (ESO) and corporate social responsibility (CSR) on environmental performance, our understanding is to see the mediating effect of green capability between ESO, CSR, and environmental performance is lacking. Data were collected by using survey questionnaires from top management of the construction and manufacturing industry in Malaysia. A total of 377 questionnaires become part of the final analysis. The researchers used SmartPLS 3.2.8 and SPSS 25.0 for analysis. The structural equation modeling (SEM) was followed to determine the variables validity and path relationships. The findings elucidate that ESO and green capability are significantly associated with environmental performance. In contrast, CSR has no direct influence on environmental performance. Moreover, ESO and CSR significantly influence green capability. Green capability mediates between ESO, CSR, and environmental performance.
Effects of corporate social responsibility on employee commitment and corporate reputation: Evidence from a transitional economy
Authors: Ramayah Thurasamy , Falahat Mohammad , Soto‐Acosta Pedro 
Published: May 2022

AbstractSome may argue that corporate social responsibility (CSR) leads companies to shift from a profit‐maximising objective to a more social one, while others argue that CSR enhances value and profitability by attracting, motivating and retaining personnel which, in return, improve customer relations and boost company reputation. The benefits from CSR may be interlinked, if not mutually reinforcing. This paper intends to empirically explore the impact of CSR practices on corporate reputation by analysing the mediation effect of employee commitment in that relationship. A total of 406 questionnaires were collected from 169 corporations in Malaysia. The proposed research model and its associated hypotheses were tested by using partial least squares (PLS) structural equation modelling (SEM). Results revealed that CSR has a positive effect on organisational reputation and that employee commitment mediates the relationship between CSR activities and corporate reputation. The main conclusions of this study can be valuable to organisations that intend to explore or exploit opportunities regarding the implementation of CSR.
In vivo glia‐to‐neuron conversion: pitfalls and solutions
Authors: Wang Lei‐Lei , Zhang Chun‐Li 
Published: May 2022

AbstractNeuron loss and disruption of neural circuits are associated with many neurological conditions. A key question is how to rebuild neural circuits for functional improvements. In vivo glia‐to‐neuron (GtN) conversion emerges as a potential solution for regeneration‐based therapeutics. This approach takes advantage of the regenerative ability of resident glial cells to produce new neurons through cell fate reprogramming. Significant progress has been made over the years in this emerging field. However, inappropriate analysis often leads to misleading conclusions that create confusion and hype. In this perspective, we point out the most salient pitfalls associated with some recent studies and provide solutions to prevent them in the future. The goal is to foster healthy development of this promising field and lay a solid cellular foundation for future regeneration‐based medicine.
Dithiocyanation of Alkynes with N‐Thiocyanato‐dibenzenesulfonimide and Ammonium Thiocyanate
Authors: Duan Yongjie , Liang Kun , Yin Hongquan , Chen Fu‐Xue 
Published: May 2022

AbstractOrganic thiocyanates widely exist in natural products, and act as important precursors for organic synthesis. An efficient dithiocyanation of alkynes with N‐thiocyanato‐dibenzenesulfonimide (NTSI) as the SCN+ cation and ammonium thiocyanate as the SCN‐ anion sources has been developed. Highly active electrophilic reagent NTSI could react with various types of alkynes to build C(sp2)−SCN bond to provide a variety of dithiocyanato olefin compounds under simple and mild conditions. Trace amount of water is beneficial to the dissociation of ammonium thiocyanate, which makes the SCN‐ anion easier to participate in the reaction. The protocol owns a broad substrates scope including terminal and internal, alkyl and aryl alkynes, excellent functional group tolerance and good regioselectivity.
Temporal properties of pain contrast enhancement using repetitive stimulation
Authors: Szikszay Tibor M. , Adamczyk Waclaw M. , Lévénez Juliette L. M. , Gouverneur Philip , Luedtke Kerstin 
Published: May 2022

AbstractBackgroundOffset analgesia (OA) is characterized by a disproportionately large reduction in pain following a small decrease in noxious stimulation and is based on temporal pain contrast enhancement (TPCE). The underlying mechanisms of this phenomenon are still poorly understood. This study is aiming to investigate whether TPCE can also be induced by repetitive stimulation, i.e., by stimuli clearly separated in time.MethodsA repetitive TPCE paradigm was induced in healthy, pain‐free subjects (n = 33) using heat stimuli. Three different interstimulus intervals (ISIs) were used: 5, 15, and 25 s. All paradigms were contrasted with a control paradigm without temperature change. Participants continuously rated perceived pain intensity. In addition, electrodermal activity (EDA) was recorded as a surrogate measure of autonomic arousal.ResultsTemporal pain contrast enhancement was confirmed for ISI 5 s (p < 0.001) and ISI 15 s (p = 0.005) but not for ISI 25 s (p = 0.07), however, the magnitude of TPCE did not differ between ISIs (p = 0.11). A TPCE‐like effect was also detected with increased EDA values.ConclusionsTPCE can be induced by repetitive stimulation. This finding may be explained by a combination of the mechanisms underlying the OA and a facilitated pain habituation.SignificanceThis experiment shows for the first time that temporal contrast enhancement of pain can be elicited by stimuli that are clearly separated in time with an interstimulus interval below 25 s.
Voltammetric study of new psychoactive substance 3‐fluorophenmetrazine
Authors: Jiroušková Eliška , Čabala Radomír , Sokolová Romana 
Published: May 2022

AbstractElectrochemical oxidation of the new psychoactive substance 3‐fluorophenmetrazine (FPM) was studied in phosphate buffers by cyclic voltammetry and differential pulse voltammetry (DPV) on a glassy carbon electrode. The redox potential of FPM in buffered solution strongly depends on pH. Cyclic voltammetry behavior shows the partial influence of adsorption on the electrode process not allowing detailed analysis of the individual steps of the reaction scheme, it means the involvement of electron transfer (E) and chemical reaction (C). Nevertheless, the irreversible shape of the cyclic voltammogram is explained by the participation of hydroxylation nucleophilic addition of water (hydroxylation) after two‐electron/two‐proton oxidation of molecule at the tetrahydro‐1,4‐oxazine ring. The suggested mechanism leading to hydroxylated derivative 2‐(3‐fluorophenyl)‐3‐methyl‐5‐hydroxymorfolin is supported by the calculated highest occupied molecular orbital spatial distribution and atomic charges calculations for electrochemically formed radical cation. Infrared spectroelectrochemistry performed during oxidation in acetonitrile/water also supported the formation of this product.The analytical method of FPM determination on glassy carbon electrode was developed using DPV with an attained limit of detection = 4.7 μmol/L in phosphate buffer of pH 9. The linear range of the calibration curve is from 7.0 to 107.00 μmol/L, correlation coefficient (r) = 0.9988.
Effective Separation of Cancer‐Derived Exosomes in Biological Samples for Liquid Biopsy: Classic Strategies and Innovative Development
Authors: Xie Yujiao , Xu Xiawei , Lin Jie , Xu Yanping , Wang Jing , Ren Yong , Wu Aiguo 
Published: May 2022

AbstractLiquid biopsy has remarkably facilitated clinical diagnosis and surveillance of cancer via employing a non‐invasive way to detect cancer‐derived components, such as circulating tumor DNA and circulating tumor cells from biological fluid samples. The cancer‐derived exosomes, which are nano‐sized vesicles secreted by cancer cells have been investigated in liquid biopsy as their important roles in intracellular communication and disease development have been revealed. Given the challenges posed by the complicated humoral microenvironment, which contains a variety of different cells and macromolecular substances in addition to the exosomes, it has attracted a large amount of attention to effectively isolate exosomes from collected samples. In this review, the authors aim to analyze classic strategies for separation of cancer‐derived exosomes, giving an extensive discussion of advantages and limitations of these methods. Furthermore, the innovative multi‐strategy methods to realize efficient isolation of cancer‐derived exosomes in practical applications are also presented. Additionally, the possible development trends of exosome separation in to the future is discussed in this review.
Petrology and geochemistry of the Palaeo‐Mesoarchean Banded Iron formations (BIFs) from the central Bundelkhand greenstone belts, Bundelkhand Craton, India: Source characteristics and depositional environment
Authors: Malviya Vivek P. , Arima Makoto , Verma Sanjeet K. , K. Pati Jayanta , Shareef Mohamed , L. Dora Muduru , K. Singh Vinod , Prakash Satya , Shukla Mayank 
Published: May 2022

Palaeo‐Mesoarchean Banded Iron formations (BIFs) of central Bundelkhand greenstone belts occur from Babina (in the west) to Mahoba (in the east) via Mauranipur along with the E–W trending of the Bundelkhand Tectonic Zone (BTZ). In the present study, we report petrological, geochemical, and mineralogical data of BIFs from the Babina, Mauranipur, and Mahoba greenstone belts of central Bundelkhand Greenstone Complex to address their source characteristics and deposition environment. The lithological association of BIFs in the Babina and Mauranipur greenstone belts consists of pillowed basic–ultrabasic volcanics and metasediments, whereas in the Mahoba greenstone belt, BIFs and quartzite occur within basic volcanics. These lithological associations collectively suggest that the entire succession was deposited in a marine environment. Based on geological setting, they are classified as Algoma‐type. The main mineral assemblages of the Babina and Mauranipur BIFs are composed of magnetite, quartz, ±garnet, hornblende, chlorite, and apatite, whereas the Mahoba BIFs along with magnetite and quartz, poised of two distinct mineral assemblages; the first one is Opx–Cpx–Grt and the other one is Grt–Hbl. The preliminary P–T study of these BIFs implies that they had gone through amphibolite‐ to granulite‐facies metamorphism. The geochemical characteristics show that BIFs from the Babina and Mauranipur greenstone belts are dominated by higher quartz and magnetite (total content = 90.63–99.95 wt.%), whereas the Mahoba greenstone belt is characterized by lesser quartz and magnetite components (total content = 86.68–94.58 wt.%). The PAAS (Post Archean Average of Australian Sediments)‐normalized REE patterns display significant positive Eu anomaly (Eu/Eu* up to 2.50) with well‐represented negative Ce anomalies (Ce/Ce* = 0.27–1.20). The REE and trace element ratios of BIFs from the Babina and Mauranipur greenstone belts suggest that they were formed by high‐T hydrothermal fluid activity without or very less continental input. Moreover, the Mahoba greenstone belt BIFs are formed by low‐T hydrothermal fluid activity with substantial continental input. Their chemical variation suggests the shallowing of the proto‐basin from the Babina in the west to Mahoba in the east. Tectonic discrimination plots imply the BIFs of the Babina, Mauranipur, and Mahoba greenstone belts of the central Bundelkhand Greenstone Complex are formed in a back‐arc tectonic setting.
Influence of nonlinear thermal radiation on mixed convective hybrid nanofluid flow about a rotating sphere
Authors: Patil Prabhugouda M. , Doddagoudar Shivanandappa H. , Shankar Hadapad F. 
Published: May 2022

AbstractThe present study investigates the mixed convective hybrid nanofluid flow over a rotating sphere under the impact of nonlinear thermal radiation. A model is built to examine the heat transport performance of ferrimagnetic magnetite and copper nanoparticles over a rotating sphere. Nonsimilar transformations are used to nondimensionalize the coupled nonlinear governing equations and the flow model's boundary conditions. Furthermore, the nondimensional governing equations were solved using implicit finite difference approximation and the quasilinearization technique. The impacts of the flow regime on many controlling parameters are then thoroughly addressed. Temperature patterns improve when nonlinear thermal radiation and hybrid nanofluid values increase. The fluid velocity and skin friction coefficient increase in the streamwise direction while decreasing in the rotating direction. The separation of the boundary layer is delayed as the sphere's rotation weakens. The stationary sphere has a larger boundary layer separation than the revolving sphere. The velocity distribution improves with increasing rotation parameter values while decreasing with increasing combined convection parameter values in the rotating direction. An increase in the temperature ratio parameter makes the fluid get hotter, and the Nusselt number goes down simultaneously. Nusselt number and skin friction coefficient in the rotation direction increase, while skin friction coefficient in streamwise direction reduces for increasing values of hybrid nanofluid. The velocity of the fluid enhances in the stream‐wise direction while reducing in the rotational direction with the increasing values of the combined convection parameter.
Evaluating the waste management situation and attitudes of residents in Bandung, Indonesia
Authors: Marešová Denisa , Mareš Kryštof , Alexiou-Ivanova Tatiana , Satyakti Yayan , Pilařová Tereza 
Published: May 2022

Abstract
The increasing amount of waste is becoming a crucial topic in developing countries, causing health-related and environmental issues. In past decades, the Indonesian government implemented regulations dedicated to municipal solid waste management (MSWM); unfortunately, these have not been well communicated to the public. The set tax level is inadequate for the MSWM financial needs in Bandung, Indonesia. Previous studies determined the public interest in MSWM as the critical factor of sustainable MSWM. However, this aspect is not well considered. This study investigated public perception and involvement in MSWM in Bandung. These investigations were conducted through two leading indicators: public interest in MSWM in environmental issues and willingness of inhabitants to pay for sufficient MSWM services. Using a binary probit model, it was found that age, educational level, locality, and satisfaction with MSWM practices play a significant role in the respondents' interest in MSWM, which is crucial to the public perception of MSWM. The results also demonstrate that more than 97% of respondents are not satisfied with MSWM practices, and more than 83% of respondents consider MSWM services insufficient. Awareness of essential operations such as waste handling and recycling is at a low level. On the other hand, more than 67% of respondents are interested in MSWM in connection with environmental issues and are familiar with the 3R concept (reducing waste, reusing, and recycling resources and products). Our MSWM research provides new perspectives on the public perception and involvement in Bandung that could be considered in the planning and implementation of sustainable MSWM. The results indicate that the public's perception and approach to MSWM in Bandung city should be enhanced by better education, providing sufficient awareness, and offering workshops. Integr Environ Assess Manag 2023;19:114–125. © 2022 SETAC
Regionalized chemical footprint method to identify aquatic ecotoxicity hotspots of hard disk drive rare-earth magnets
Authors: Frost Kali , Hua Inez 
Published: May 2022

Abstract
The chemical footprint (ChF), which combines life cycle assessment (LCA) and quantitative risk assessment principles, shows promise for exploring localized toxicity impacts of manufacturing processes, which is not achievable with LCA alone. An updated ChF method was applied to the global annual production of a hard disk drive (HDD) rare-earth element (REE) magnet assembly, assuming a supply chain in East and Southeast Asia. Existing REE magnet assembly LCA inventories were combined with supplier manufacturing locations to create a cradle-to-gate spatial unit process inventory. Emissions from the electricity grid for each manufacturing site were downscaled to hydrobasins of interest using the Global Power Plant Database. The predicted no effect concentration (PNEC) was chosen as the ecotoxicity pollution boundary to determine the threshold for dilution of each chemical of concern (CoC) and to calculate the ChF. Finally, a high-resolution hydrological database provided volumes of the freshwater river reach draining each hydrobasin and was used to calculate the dilution capacity (DC), that is, the volume required to remain at or below the PNEC for each CoC. The total ChF of annual REE magnet assembly production was 6.91E12 m3, with hotspots in watersheds in China and Thailand where REEs are processed and steel metalworking takes place. Metals were the primary CoCs, with cadmium and chromium(VI) comprising 77% of total ChF. Dilution factors ranged from 5E−09 to 9E + 03 of the DC of the waterbody, reflecting the spatial variability in both emissions and DC. An advanced ChF method was demonstrated for HDD REE magnets. Scoping is a key step required to reduce model complexity. The use of regionalized fate factors and standardized hydrological data sets improves the comparability of ChFs across hydrobasins. Additional work to combine data sets into readily available tools is needed to increase usability and standardization of the ChF method and promote wider adoption. Integr Environ Assess Manag 2023;19:272–283. © 2022 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals LLC on behalf of Society of Environmental Toxicology & Chemistry (SETAC).