bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical and radiological presentation of familial Mayer-Rokitansky Küster-Hauser syndrome in three sisters with literature review
Authors: Qudsieh Hana’ , Qudsieh Suhair , Mwafi Nesrin 
Published: September 2022

Abstract
Background
Mayer-Rokitansky Küster-Hauser syndrome MRKHS represents class I of congenital Müllerian anomaly, which resulted from interruption of embryonic development of the paramesonephric ducts in early pregnancy. It is characterized by uterine and proximal vaginal aplasia/hypoplasia associated with variable degree of cardiac, renal, and skeletal anomalies.
We aimed to review and analyze clinically and radiologically MRKHS relying on three young sisters’ cases who presented with primary amenorrhea and were found to have features of MRKHS.

Case presentation
Three sisters aging 17, 20, and 25 years old presented with primary amenorrhea. Clinical workup was performed followed by ultrasound and MRI of the abdomen and pelvis, spine X-ray, audiogram, echocardiogram, hormonal study, and karyotyping. The three sisters had normal sex hormones and mature secondary sexual characteristic features. Additionally, cardiac valvular regurgitation and renal hypoplasia were recognized. Cytogenetic confirmed normal female 46 XX karyotype. MRI showed variable size and appearance of Müllerian remnant tissue of the uterus and proximal vagina.

Conclusion
MRKHS shows variable size and appearance of Müllerian remnant structures; however, it seems that the smaller the volume of remnant tissue the more severe associated anomalies. Associated valvular cardiac disease is documented, which was not reported before.
3D controlled-source electromagnetic inversion in the radio-frequency band
Authors: Smirnova Maria , Shlykov Arseny , Fadavi Asghari Shiva , Tezkan Bülent , Saraev Alexander , Yogeshwar Pritam , Smirnov Maxim 
Published: September 2022

The classical radio-magnetotelluric (RMT) method is nowadays routinely applied to various environmental, engineering, and exploration problems. The technique uses radio transmitters broadcasting in the frequency range of 10 kHz to 1 MHz, and the measurements are carried out in the far field. The well-known disadvantages of RMT are a lack of robust radio transmitters in remote areas; the absence of transmitters broadcasting below 10 kHz, which limits the penetration depth; and a possible low signal-to-noise ratio. To overcome these difficulties, controlled sources can be used (controlled-source RMT [CSRMT]). We extend the CSRMT method to perform measurements not only in the far field but also in the transition zone. In CSRMT practice, it often is challenging to maintain far-field conditions for logistical reasons. Therefore, part of the measured data contains signatures of the source field, which cannot be interpreted with magnetotelluric software. In addition, the source placed directly in the survey area allows us to increase the signal-to-noise ratio and resolution. Such CSRMT in the transition zone is, in fact, a controlled-source electromagnetic method but with full impedance tensor and tipper vector transfer functions. We develop new procedures for the 3D modeling and inversion of the tensor radio-frequency data measured in the transition zone of two perpendicular horizontal electric dipole sources. In this case, the geometry of the source must be considered in the forward modeling. The developed modeling and inversion software is tested on a synthetic 3D model. The 3D resistivity models derived from the real data confirm the geologic settings and are consistent with the available borehole information. Therefore, we conclude that the CSRMT approach extended to include the source field is feasible and that the developed procedures are reliable.
Cognitive trajectories following onset of psychosis: a meta-analysis
Authors: Watson Andrew J. , Harrison Lauren , Preti Antonio , Wykes Til , Cella Matteo 
Published: September 2022

BackgroundCognitive impairment is a core feature of schizophrenia, associated with poor functional outcomes. The course of cognitive function in the years following illness onset has remained a subject of debate, with a previous analysis finding no worsening, providing support for the neurodevelopmental model of schizophrenia. Since then, many more studies have reported on longitudinal cognitive performance in early psychosis, with some indicating deterioration, which does not align with this view.AimsThis study aims to quantitatively review the literature on the longitudinal trajectory of cognitive deficits in the years following psychosis onset, in comparison with healthy controls. It is the first to also synthesise longitudinal data on social cognition.MethodElectronic databases (‘PubMed’, ‘PsycInfo’ and ‘Scopus’) were searched (to end September 2021). Meta-analyses of 25 longitudinal studies of cognition in early psychosis were conducted (1480 patients, 789 health controls). Unlike previous analyses, randomised controlled trials and those with multiple cognitive testing periods within the first year were excluded to minimise bias (PROSPERO, ID: CRD42021241525).ResultsSmall improvements were observed for global cognition (g = 0.25, 95% CI 0.17–0.33) and individual cognitive domains, but these were comparable with healthy controls and likely an artefact of practice effects.ConclusionsThere is no evidence of continued cognitive decline or improvement in the early years following psychosis onset, with a need for more studies over longer follow-up periods. Practice effects highlight the importance of including control samples in longitudinal and intervention studies. Further data are needed to evaluate the course of social cognition subdomains.
Pivotal role of STIP in ovule pattern formation and female germline development in Arabidopsis thaliana
Authors: Petrella Rosanna , Gabrieli Flavio , Cavalleri Alex , Schneitz Kay , Colombo Lucia , Cucinotta Mara 
Published: September 2022

ABSTRACT
In spermatophytes the sporophytic (diploid) and the gametophytic (haploid) generations co-exist in ovules, and the coordination of their developmental programs is of pivotal importance for plant reproduction. To achieve efficient fertilization, the haploid female gametophyte and the diploid ovule structures must coordinate their development to form a functional and correctly shaped ovule. WUSCHEL-RELATED HOMEOBOX (WOX) genes encode a family of transcription factors that share important roles in a wide range of processes throughout plant development. Here, we show that STIP is required for the correct patterning and curvature of the ovule in Arabidopsis thaliana. The knockout mutant stip-2 is characterized by a radialized ovule phenotype due to severe defects in outer integument development. In addition, alteration of STIP expression affects the correct differentiation and progression of the female germline. Finally, our results reveal that STIP is required to tightly regulate the key ovule factors INNER NO OUTER, PHABULOSA and WUSCHEL, and they define a novel genetic interplay in the regulatory networks determining ovule development.
How a better understanding of nursing research roles may help to embed research into clinical structures
Authors: Smythe Analisa , Carter Vanda , Dube Alisen , Cannaby Ann-Marie 
Published: September 2022

Background: Despite efforts to build research capacity within nursing there are growing concerns about the lack of funding and support for nurses who wish to pursue a career in research. Aim: To explore how research capacity within the nursing profession can be increased. Discussion: The disparity in opportunity and support for such roles is a barrier to the growth of nursing research. This article examines the nomenclature that exists around nursing roles in research, including those of clinical research nurse, nurse researcher and clinical nurse academic, and the challenges associated with each of these roles. The authors reflect on their career paths, specifically the transition from clinical research nurse to nurse researcher. Conclusion: To grow research capacity within the nursing discipline, organisations must provide opportunities for research at all career stages, promote the fundamental role that research plays in the quality of patient care and highlight career pathways and roles in nursing research.
Exploring the psychological impacts of a gestational cancer diagnosis on women: a literature review
Authors: Roberts Freya , Andrewes Tanya 
Published: September 2022

Background: One in 1000 women are diagnosed with gestational cancer in the UK. Of these, the greatest number are breast cancer diagnoses. The rate of gestational cancer is expected to increase due to women choosing to become pregnant later in life. Aims: To explore the experiences of women with a gestational cancer diagnosis to identify how the support provided to them by the multidisciplinary team could be enhanced. Method: A systematic literature review using Medline, CINAHL Complete and Complementary Index. Seven primary research articles were selected for in-depth analysis. Thematic analysis was completed and developed with academic and peer supervision. Findings: Three themes were identified: ‘time pressures and decision-making, balanced with concerns for the health and wellbeing of the baby and self’; ‘fears about parenting’ and ‘the influence of support’. Within all themes, distress was most commonly caused by poor or inconsistent communication between health professionals, which left women feeling disempowered and anxious about decision-making. Conclusion: Women diagnosed with gestational cancer have unique support needs arising from receipt of a devastating diagnosis at what should be a happy time. The experience of being under the care of two discrete teams can result in uncertainty and distress when inconsistent messages about treatment are given. Support can be significantly enhanced by having a named midwife who attends all multidisciplinary team meetings about the woman concerned, who can assess for distress and who can signpost psychosocial support, based on the individual woman's needs.
Nutritional assessment and associated factors in children with congenital heart disease—Ethiopia
Authors: Tsega Temesgen , Tesfaye Tigist , Dessie Azene , Teshome Tesfalem 
Published: September 2022

Introduction
Worldwide, congenital heart disease is the principal heart disease in children and constitutes one of the major causes of infant mortality, particularly in developing countries. Infants and children with congenital heart disease exhibit a range of delays in weight gain and growth. In some instances, the delay can be relatively mild, whereas in other cases, cause the failure to thrive.

Objectives
To determine the nutritional status and associated factors of pediatric patients with congenital heart disease.

Material and method
A cross sectional analytical study conducted over a period of 6 months (Feb to Jul 2020). A total of 228 subjects with congenital heart disease who visited the cardiac center during the study period where included until the calculated sample size attained. Data is collected from patient’s card and their care giver. Data was then analyzed using Statistical Package for Social Sciences (SPSS) for windows version 25.0. Odds Ratio with 95% Confidence Interval (CI) was used to determine the effect of the independent variables on the outcome variable and P-value less than 0.05 was considered statistically significant.

Results
A total of 228 children ranging from 3month to 17yrs of age with mean age of 4.7 years (SD = 3.8 years) were included in the study. Most of the subjects had acyanotic heart disease accounting for 87.7%. The overall prevalence of wasting, underweight and stunting were 41.3%, 49.1% and 43% respectively. Children with congenital heart disease and having pulmonary hypertension, were found more likely to develop wasting compared to those without pulmonary hypertension with an odds of 1.9 (95% CI: 1.0–3.4) and also have greater chance of stunting with an odds of 1.9 (95% CI: 1.0–3.4). Children 5 to 10 years of age were 2.3 times more likely to be underweight.

Conclusion
Malnutrition is a major problem in pediatric patients with congenital heart disease. Pulmonary hypertension and older age are associated with increased risk of undernutrition.
Prediction models for the prediction of unplanned hospital admissions in community-dwelling older adults: A systematic review
Authors: Klunder Jet H. , Panneman Sofie L. , Wallace Emma , de Vries Ralph , Joling Karlijn J. , Maarsingh Otto R. , van Hout Hein P. J. 
Published: September 2022

BackgroundIdentification of community-dwelling older adults at risk of unplanned hospitalizations is of importance to facilitate preventive interventions. Our objective was to review and appraise the methodological quality and predictive performance of prediction models for predicting unplanned hospitalizations in community-dwelling older adultsMethods and findingsWe searched MEDLINE, EMBASE and CINAHL from August 2013 to January 2021. Additionally, we checked references of the identified articles for the inclusion of relevant publications and added studies from two previous reviews that fulfilled the eligibility criteria. We included prospective and retrospective studies with any follow-up period that recruited adults aged 65 and over and developed a prediction model predicting unplanned hospitalizations. We included models with at least one (internal or external) validation cohort. The models had to be intended to be used in a primary care setting. Two authors independently assessed studies for inclusion and undertook data extraction following recommendations of the CHARMS checklist, while quality assessment was performed using the PROBAST tool. A total of 19 studies met the inclusion criteria. Prediction horizon ranged from 4.5 months to 4 years. Most frequently included variables were specific medical diagnoses (n = 11), previous hospital admission (n = 11), age (n = 11), and sex or gender (n = 8). Predictive performance in terms of area under the curve ranged from 0.61 to 0.78. Models developed to predict potentially preventable hospitalizations tended to have better predictive performance than models predicting hospitalizations in general. Overall, risk of bias was high, predominantly in the analysis domain.ConclusionsModels developed to predict preventable hospitalizations tended to have better predictive performance than models to predict all-cause hospitalizations. There is however substantial room for improvement on the reporting and analysis of studies. We recommend better adherence to the TRIPOD guidelines.
How do people think about the implementation of speech and video recognition technology in emergency medical practice?
Authors: Kim Ki Hong , Hong Ki Jeong , Shin Sang Do , Ro Young Sun , Song Kyoung Jun , Kim Tae Han , Park Jeong Ho , Jeong Joo 
Published: September 2022

BackgroundRecently, speech and video information recognition technology (SVRT) has developed rapidly. Introducing SVRT into the emergency medical practice process may lead to improvements in health care. The purpose of this study was to evaluate the level of acceptance of SVRT among patients, caregivers and emergency medical staff.MethodsStructured questionnaires were developed for the patient or caregiver group and the emergency medical staff group. The survey was performed in one tertiary academic hospital emergency department. Questions were optimized for each specific group, and responses were provided mostly using Likert 5-scales. Additional multivariable logistic regression analyses for the whole cohort and subgroups were conducted to calculate odds ratios (OR) and confidence intervals (CI) to examine the association between individual characteristics and SVRT acceptance.ResultsOf 264 participants, respondents demonstrated a positive attitude and acceptance toward SVRT and artificial intelligence (AI) in future; 179 (67.8%) for video recordings, and 190 (72.0%) for speech recordings. A multivariable logistic regression model revealed that several factors were associated with acceptance of SVRT in emergency medical practice: belief in health care improvement by signal analysis technology (OR, 95% CIs: 2.48 (1.15–5.42)) and AI (OR, 95% CIs: 1.70 (0.91–3.17)), reliability of AI application in emergency medicine (OR, 95% CIs: 2.36 (1.28–4.35)) and the security of personal information (OR, 95% CIs: 1.98 (1.10–3.63)).ConclusionA high level of acceptance toward SVRT has been shown in patients or caregivers, and it also appears to be associated with positive attitudes toward new technology, AI and security of personal information.
STUDI KOMPARASI REGULASI TELEKONSULTASI ANTARA INDONESIA DENGAN SINGAPURA
Authors: Budiyanti Rani Tiyas , Suryoputro Antono , Murni Murni , Herlambang Penggalih Mahardika 
Published: September 2022

Telekonsultasi telah berkembang di Indonesia terlebih di masa pandemi Coronavirus Disease -19 (COVID-19). Teknologi ini merupakan layanan konsultasi kesehatan jarak jauh yang merupakan bagian dari telemedisin. Indonesia telah mengatur pelaksanaan telemedisin melalui Permenkes Nomor 20 tahun 2019 mengenai Penyelenggaraan Telemedisin. Meskipun demikian, regulasi tersebut belum spesifik mengatur tentang telekonsultasi, terutama mengenai startup telekonsultasi yang saat ini banyak bermunculan. Penelitian ini bertujuan untuk mengetahui perbandingan regulasi mengenai telekonsultasi yang ada di Indonesia dengan negara lain yaitu Singapura. Penelitian ini merupakan penelitian normatif dengan pendekatan perundang-undangan (statue approach) dan pendekatan komparatif (comparative approach). Bahan hukum primer diperoleh dari peraturan perundang-undangan maupun yurisprudensi. Sedangkan bahan hukum sekunder diperoleh dari jurnal, buku, maupun prosiding mengenai regulasi terkait konsultasi. Berdasarkan penelitian, telekonsultasi yang dilakukan di Indonesia hanya diperbolehkan jika terintegrasi dengan fasilitas pelayanan kesehatan tertentu. Selain itu, regulasi mengenai monitoring, pertanggung jawaban dan keamanan data masih belum detail dan spesifik. Sanksi bagi startup yang menyelenggarakan layanan konsultasi kesehatan mandiri pun belum jelas dan tegas. Singapura memiliki regulasi telekonsultasi yang tercantum dalam regulatory sandbox sehingga dapat menjembatani layanan konsultasi kesehatan online yang diselenggarakan oleh startup yang ada dengan syarat tertentu. Regulasi mengenai telekonsultasi di Indonesia perlu disusun lebih detail, spesifik, dan jelas sehingga masyarakat dapat memperoleh layanan konsultasi kesehatan yang aman dan dapat dipertanggungjawabkan.
Design and analysis of series and parallel circuits based on plasmonic waveguides for high-performance computing devices
Authors: Jain Satyendra , Choudhary Kuldeep , Kumar Santosh 
Published: September 2022

Abstract
Nowadays, mental–insulator–metal (MIM) waveguides are widely used in the design of optical plasmonic waveguides due to their superior ability to confine surface plasmons up to sub wavelength scale. This research proposes the design of series and parallel circuits using cascaded plasmonic Mach–Zehnder interferometers (PMZIs). Each PMZI employs a nonlinear arm to switch light across the output port via the insertion of the nonlinear Kerr material poly(2-methoxy-5-(28-ethylhexyloxy)-PPV). The proposed design is having footprint of 104 µm × 11 µm. The finite-difference time-domain method is used to study, design, and analysis all optical series and parallel circuit proposals.
A posteriori regularization method for the two-dimensional inverse heat conduction problem
Authors: Cheng Wei , Liu Yi-Liang , Zhao Qi 
Published: September 2022

Abstract
In this article, we consider a two-dimensional inverse heat conduction problem that determines the surface temperature distribution from measured data at the fixed location. This problem is severely ill-posed, i.e., the solution does not depend continuously on the data. A quasi-boundary value regularization method in conjunction with the a posteriori parameter choice strategy is proposed to solve the problem. A Hölder-type error estimate between the approximate solution and its exact solution is also given. The error estimate shows that the regularized solution is dependent continuously on the data.
The mediating role of comments’ credibility in influencing cancer cure misperceptions and social sharing
Authors: Liu Juan , Reif-Stice Carrie , Getz Bruce 
Published: September 2022

Abstract

Purpose
The rise of fake news is an increasing issue for cancer patients. Specifically, the use of cannabis as a cure for cancer is the most shared social media content regarding alternative cancer treatments (Shi, Siyu, Arthur R. Brant, Aaron Sabolch & Erqi Pollom. 2019. False news of a cannabis cancer cure. Cureus 11(1). e3918. DOI:10.7759/cureus.3918). To better understand the relationship between fake news, perceived credibility, social sharing, and belief in health misinformation, we conducted an online experiment in the United States to explore how people react to fake cancer news on Facebook.

Design/methodology/approach
A four-condition between-subjects online experiment was conducted to examine whether the perceived credibility of information and comments serve as mediating factors to influence misperceptions and social sharing of cancer misinformation.

Findings
We find that it is the comments’ credibility rather than information credibility that acts as a mediator between the effects of exposure to variations of comments on cancer treatment misperceptions and social sharing intentions.

Practical implications
Our study provides important insights into correcting health misinformation on social media. Findings demonstrate the importance of healthcare professionals and organizations engaging with misleading and potentially harmful misinformation posted. Additionally, practitioners need to provide training to enhance individuals’ media literacy to better discern credible health information from misinformation on social media.

Value
The study advances prior misinformation correction and credibility literature. Theoretically, we find that perceived comments’ credibility act as a mediator in mitigating the spread of fake news. Furthermore, exposure to variations of corrective comments (vs. peers’ supportive comments) increased cancer cure misperceptions via comments’ credibility, a backfire effect indicating that cancer cure misperceptions persisted, were complicated, and difficult to correct.
Exploring the Sources of Consumer-Based Brand Equity in the Cryptocurrency Market
Authors: Boukis Achilleas 
Published: September 2022

Abstract
The present study adopts a qualitative approach to explore the nature and sources of consumer-based brand equity (CBBE) in the cryptocurrency market. Drawing on thirty-two semi-structured interviews with crypto investors in the UK, our findings reveal three main sources of CBBE for crypto brands (i.e. blockchain-based features, crypto brand identity, psychological factors). Also, we supply insights into how the nature and features of blockchain technology shape consumers’ attitude towards crypto brands. Our findings also reveal the key elements of cryptos’ brand identity (i.e. white papers, brand purpose, ICOs) as well as various psychological factors (i.e. psychological distance, escapism, curiosity) that shape consumer perceptions of crypto brands. Our work extends the cryptocurrency and branding literatures in identifying the main sources of CBBE in the crypto market.