bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multifaceted Therapeutic Approaches for the Management of Dyspareunia: A Narrative Review
Authors: Rastogi Muskan , Deka Kuldeep , Krishnan K Shyam , Narayan Amitesh , Nayak Megha M , Kumar K Vijaya 
Published: January 2025

Background
Dyspareunia is a complex health issue in women and causes an increased risk of sexual dysfunction, relationship conflict, mood disorders, and decreased quality of life. This narrative review aimed to explore the different therapeutic approaches for managing this complex health problem among the women population.

Materials and Methods
Articles published in English in Google Scholar, PubMed, Scopus, ScienceDirect, Embase, CINAHL, Cochrane Library, and SAGE databases from 2017 to 2023 were searched. Twelve studies with dyspareunia as the primary clinical problem were chosen. The clinical efficacy of pelvic floor muscle training, perineal massage, biofeedback, manual therapy, dilator therapy, extracorporeal shockwave therapy, and visceral manipulation in the management of dyspareunia was evaluated in these articles.

Results
The literature review revealed that diverse interventions offer valuable options for managing dyspareunia, which can be tailored care to the individual patient’s requirement based on clinical evaluation decisions. This study summarized the multi-modal adjuvant therapeutic options for dyspareunia management.

Conclusion
From this review, it could be concluded that there is no consolidated evidence regarding the relative efficacy or effectiveness of various therapeutic interventions for managing dyspareunia. In light of the findings of this review, it could be safely said that a patient-centric eclectic approach incorporating different therapeutic modes will be most appropriate for the management of dyspareunia.
Effects of metformin on postprandial blood pressure, heart rate, gastric emptying, GLP-1 and the prevalence of postprandial hypotension in type 2 diabetes – a double-blind, placebo-controlled crossover study
Authors: Quast Daniel R. , Xie Cong , Bound Michelle J. , Grivell Jacqueline , Hatzinikolas Seva , Jones Karen L. , Horowitz Michael , Rayner Christopher K. , Nauck Michael A. , Meier Juris J. , Phillips Liza K. , Wu Tongzhi 
Published: January 2025

Individuals with type 2 diabetes are at high risk of postprandial falls in blood pressure (BP) (i.e., a reduction in systolic BP of ≥20mmHg, termed postprandial hypotension (PPH)), which increases the risk of falls and mortality. This study evaluated the effects of oral metformin on postprandial BP, heart rate (HR), glucagon-like peptide-1 (GLP-1) and gastric emptying (GE) in individuals with type 2 diabetes.
We studied 16 subjects (5 female) before and after ingestion of a 75g radiolabeled glucose drink, after both acute (30 min) and subacute (b.i.d for 7 days) administration of metformin (850mg) or placebo, in a double-blind, randomized, crossover design. 24-hour ambulatory BP measurement following standardized meals (breakfast, lunch and dinner) was used to quantify PPH events. The primary outcome was the postprandial fall in systolic BP.
We found that acute administration of metformin did not affect BP, HR, plasma insulin or GLP-1 levels, but slowed GE (P&lt;0.001) and reduced the glycemic response to oral glucose (P&lt;0.001). Sub-acute metformin reduced PPH events by 32% (P=0.035), in association with an increase in HR (P=0.029), slowing of GE (P&lt;0.001), augmentation of plasma GLP-1 (P&lt;0.001), and a reduction in plasma glucose (P&lt;0.001) without affecting plasma insulin. Pre-prandial BP was unaffected by metformin.
To conclude, in type 2 diabetes oral metformin attenuates the hypotensive response to meals, associated with stimulation of GLP-1 and slowing of GE to reduce PPH.
Association of socio-demographic characteristics, comorbidities, lifestyle habits, and saliva parameters with dental caries in adults with obesity
Authors: Chuy Virginie , Mayoute Marie , Monsaingeon-Henry Maud , Gatta-Cherifi Blandine , Arrivé Élise 
Published: January 2025

Objective: To describe the oral health status of patients with obesity and to explore the socio-demographic characteristics, comorbidities, lifestyle habits (tobacco, alcohol, sweet/acidic diet), and saliva parameters most associated with the dental caries experience.
Material and methods: We conducted a cross-sectional analysis of 204 patients’ data with obesity attending a therapeutic education programme. Caries experience (number of decayed, missing, and filled teeth [DMFT]), periodontal status, oral hygiene, occlusal tooth wear, masticatory inefficiency, and saliva parameters were recorded.
Results: Mean DMFT was 12 ± 7 and was independently associated with age (mean 47 ± 14 years; for 1 standard deviation (SD) increase: β = 0.22, 95% confidence interval [CI] = 0.16–0.29), female sex (72%; β = 3.76, 95% CI = 1.65–5.87), brushing <2 times/day (35%; β = 2.86, 95% CI = 0.81–4.90), salivary buffering capacity (low [46%] vs. normal [40%]: β = 2.02, 95% CI = 0.08–3.95; very low [10%] vs. normal: β = 3.34, 95% CI = 0.31–6.37), and salivary consistency (bubbly [30%] vs. clear [57%]: β = 2.45, 95% CI = 0.52–4.38).
Conclusions: Improving patients’ competencies for oral care, such as teeth brushing twice daily, is necessary to limit the burden of dental caries in individuals with obesity. Acting on salivary composition may also be of interest, and further studies are required to explore the underlying mechanisms.
Students' Cognitive, Affective, Behavioural and Social Engagement in Collaborative Writing
Authors: Addinna Ainul , Ovilia Ririn , Solusia Carbiriena , Ramadhani Syafitri 
Published: January 2025

One of the effective strategies to improve writing skills is Collaborative Writing (CW). In the CW process, group members will engage and interact in the process of writing a text. Hence, student engagement becomes an important point that needs to be studied. Based on the EWT (Engagement with the Task) model from Philip and Duchesne, there are 4 dimensions of student engagement, namely cognitive, affective, attitudinal and social engagement. This research aims to analyze students' cognitive, affective, behavioral and social engagement in learning academic writing using collaborative writing method. Based on this objective, the appropriate research design is qualitative research using observation as a data collection technique and the instruments used are observation sheets and field notes supported by video recording during the learning process. From the results of the analysis conducted, it was found that during Collaborative Writing with peers the majority of participants in this study were involved cognitively, affectively and attitudinally. In terms of social engagement, the patterns of all pairs were collaborative and expert/novice relationship
SHARIA ECONOMIC LAW ON LEGAL PROTECTION IN MIXED RICE TRANSACTIONS IN PALOLO DISTRICT
Authors: Cahaya Yunika , Oktafian Mohamad , Ruslan Murniati 
Published: January 2025

This research examines the practice of rice blending at Tiga Putri Enterprises, which does not fully follow the principles of transparency stipulated in sharia economic law and consumer protection law in Indonesia. Without notice to consumers, this practice can be categorized as tadlis or fraud under sharia law, which obscures product quality and creates the potential for consumer dissatisfaction or loss. This study used an interview method to explore consumer perceptions regarding product information and business responsibility in delivering quality goods. The results show that the lack of information transparency makes consumers less aware of product quality, resulting in a decline in trust. The implications of the study highlight the importance of regulation and education on transparency in the buying and selling of rice, in order to build a fairer and more responsible trading environment in accordance with sharia principles and consumer protection in Indonesia.
Abstrak
Penelitian ini meneliti praktik pencampuran beras di Usaha Tiga Putri yang tidak sepenuhnya mengikuti prinsip transparansi yang diatur dalam hukum ekonomi syariah dan hukum perlindungan konsumen di Indonesia. Tanpa adanya pemberitahuan kepada konsumen, praktik ini dapat dikategorikan sebagai tadlis atau penipuan menurut hukum syariah, yang mengaburkan kualitas produk dan menimbulkan potensi ketidakpuasan atau kerugian bagi konsumen. Studi ini menggunakan metode wawancara untuk menggali persepsi konsumen terkait informasi produk dan tanggung jawab usaha dalam penyampaian kualitas barang. Hasil penelitian menunjukkan bahwa kurangnya transparansi informasi membuat konsumen kurang memahami kualitas produk, sehingga terjadi penurunan kepercayaan. Implikasi penelitian menyoroti pentingnya regulasi dan edukasi transparansi dalam jual beli beras, demi membangun lingkungan perdagangan yang lebih adil serta bertanggung jawab sesuai prinsip syariah dan perlindungan konsumen di Indonesia.
Aktivitas Antibakteri Escherichia coli Pada Berbagai Konsentrasi Lignin Dari Serat Serabut Kelapa (Cocos nucifera L)
Authors: Wahyudiyono Aditya Ivan , Dewi Anggreni Anak Agung Made , Antara I Wayan 
Published: January 2025

ABSTRACT

Lignin as one of the phenolic compounds can be used as an antibacterial substance that has renewable properties, is easily decomposed by the environment, and its availability is abundant in nature. The purpose of this study is to determine the effect of lignin concentration from coconut fiber on the antibacterial activity of Escherichia coli and determine the concentration of lignin from coconut fiber that produces the highest antibacterial activity of Escherichia coli. This study used a completely randomized design (CRD) with lignin concentration treatment (K) consisting of 6 levels, namely antibiotics, 0 percent, 5 percent, 10 percent, 15 percent, and 20 percent. The variable observed was the diameter of the inhibition zone against E. coli bacteria. The results of the analysis of variance showed that the concentration of lignin had a very significant effect on the diameter of the inhibition zone of E. coli bacteria. Lignin concentration of 20 percent produced the highest inhibition zone diameter of 7,11 mm.
Keywords : Coconut fiber, lignin, antibacterial, Eschericia coli

ABSTRAK

Lignin sebagai salah satu senyawa fenolik yang dapat digunakan sebagai zat antibakteri dan memiliki sifat renewable, mudah teruraikan oleh lingkungan, dan ketersediaannya melimpah di alam. Tujuan dari penelitian ini adalah mengetahui pengaruh konsentrasi lignin dari serat serabut kelapa terhadap aktivitas antibakteri Escherichia coli dan menentukan konsentrasi lignin dari serat serabut kelapa yang menghasilkan aktivitas antibakteri Escherichia coli tertinggi. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) dengan perlakuan konsentrasi lignin (K) yang terdiri dari 6 taraf yaitu antibiotik, 0 persen, 5 persen, 10 persen, 15 persen, dan 20 persen. Variabel yang diamati adalah diameter zona hambat terhadap bakteri E. coli. Hasil analisis keragaman menunjukkan bahwa konsentrasi lignin berpengaruh sangat nyata terhadap diameter zona hambat bakteri E. coli. Konsentrasi lignin 20 persen menghasilkan diameter zona hambat tertinggi yaitu sebesar 7,11 mm.
Kata kunci : Serabut kelapa, lignin, antibakteri, Eschericia coli
Perbandingan Metode Ekstraksi Konvensional, Pengepresan, Dan Enzimatis Terhadap Kualitas Minyak Buah Merah (Pandanus conoidues)
Authors: Yikwa Noflin , Supriyanto Supriyanto , Hidayati Darimiyya 
Published: January 2025

Red fruit (Pandanus conoideus) is native to Papua. The fat content in red fruits varies, ranging from 11.2-30.7% (bk). The oil of red fruit comprises unsaturated fatty acids, especially oleic acid, linoleic, linoleic and palmitoleic acid, as well as various minor active components which include ?-carotene, ?-carotene, ?-cryptosantine, ?-tocopherol and phenolic acid Red fruit oil is also proven to be efficacious for health. The purpose of this study is to determine the influence of different extraction methods on the characteristics of red fruit oil. The design of this study uses a randomized design complete with the treatment of the ecclesiastical method. The extraction methods used are conventional, pressing and enzymatic. The study measured parameters such as analysis of yield, specific gravity, brightness and antioxidants. The results of the study showed that there was an influence of extraction method on the characteristics of red fruit oil. Employing the enzymatic extraction technique produced the best oil with a yield of 17.80%, a specific gravity of 0.76 g/mL, a brightness value of 20.37 and an antioxidant % of 26.05%
Keywords : antioxidant, red fruit, extraction method and enzymatic
Buah merah (Pandanus conoideus) merupakan tanaman endemik Papua. Kandungan lemak dalam buah merah bervariasi, berkisar antara 11,2-30,7% (bk). Minyak buah merah mengandung asam lemak tak jenuh terutama asam oleat, linoleat, linoleat dan palmitoleat, serta berbagai komponen aktif minor yang meliputi ?-karoten, ?-karoten, ?-cryptosantin, ?-tokoferol dan asam fenolik Minyak buah merah juga terbukti berkhasiat untuk kesehatan. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh perbedaan metode ekstraksi terhadap karakteristik minyak buah merah. Desain penelitian ini menggunakan rancangan acak lengkap dengan perlakuan metode ekstaksi. Metode ekstraksi yang digunakan adalah secara konvensional, pengepresan dan enzimatis. Parameter yang diamati meliputi analisa rendemen, berat jenis, kecerahan dan antioksidan. Hasil penelitian menunjukkan ada pengaruh metode ekstraksi terhadap karakteristik minyak buah merah. Ekstraksi menggunakan metode enzimatis mengahasilkan minyak yang paling baik dengan jumlah rendemen 17,80%, , berat jenis 0,76 g/mL, nilai kecerahan 20,37 dan % antioksidan 26,05%
Kata kunci : antioksidan, buah merah, metode ekstraksi dan enzimatis
Perencanaan Produksi Agregat Telur Asin Kelompok Wanita Tani (KWT) Kenanga Kuningan Jawa Barat
Authors: Salam Jaenal Gopur Asmanul , Kartika Kartika , Nuraeni Riani 
Published: January 2025

The purpose of this study is to forecast demand for salted eggs for the Kenanga Women Farmers Group (KWT) for the next 6 months and a comparison of the level strategy and chase strategy in aggregat planning that can minimize production cost of the Kenanga Women Farmers Group (KWT). The data used in this research is by looking at the historical data of the Kenanga Women Farmer Group (KWT) salted eggs and information related to the research objectives. The data analysis technique is by making a demand forecast using the moving average and exponential smoothing method. Then the forecasting results that have the smallest error rate are used to make aggregate planning using the strategy level method and the chase strategy. The result showed that the production cost of Kenanga Womens Farmers Group (KWT) with the chase strategy method was smaller than the level strategy method, where the production cost with the chase strategy method was Rp. 17.959.950. Weanwhile, the level strategy method is Rp.17.961.817,5. So that the chase strategy method is very suitable to be applied at Kenanga Women Farmer Group (KWT) in minimizing production costs.
Keywords : Aggregat planning, demand forecasting, level strategy, chase strategy
Tujuan dari penelitian ini yaitu untuk meramalkan permintaan telur asin Kelompok Wanita Tani (KWT) Kenanga selama 6 bulan kedepan serta perbandingan level strategy dan chase strategy dalam perencanaan agregat yang dapat meminimalkan biaya produksi Kelompok Wanita Tani (KWT) Kenanga. Data yang digunakan dalam penelitian ini yaitu dengan cara melihat data historis telur asin Kelompok Wanita Tani (KWT) Kenanga serta informasi yang berkaitan dengan tujuan penelitian. Teknik analisis data yaitu dengan cara membuat peramalan permintaan dengan metode moving average dan exponential smoothing. Kemudian hasil peramalan yang memiliki tingkat kesalahan yang paling kecil digunakan untuk membuat perencanaan agregat dengan menggunakan metode level strategy dan chase strategy. Hasil penelitian menunjukan bahwa biaya produksi Kelompok Wanita Tani (KWT) Kenanga dengan metode chase strategy lebih kecil dibandingkan metode level strategy, dimana untuk biaya produksi dengan metode chase strategy yaitu Rp.17.959.950. Sedangkan untuk metode level strategy yaitu sebesar Rp.17.961.817,5. Sehingga metode chase strategy sangat cocok di terapkan di Kelompok Wanita Tani (KWT) Kenanga dalam meminimalkan biaya produksi.
Kata kunci : Perencanaan agregat, peramalan permintaan, level strategy, chase strategy
Sign Talk Assistive Technology: Real-Time Recognition of the Libras Typical Alphabet Using Artificial Intelligence
Authors: Benevides Marcello Pereira , Xavier Kawan Ruiz Santiche Lima , Silva Arthur Pereira Syllos , Rosa Junior Orlando , Villarta Cleiton José Benedito , Richetto Marco Rogério Silva , Moura Roque Antônio de 
Published: January 2025

Objective: The objective of this research is to promote SignTalk, an innovation in assistive technology based on artificial intelligence that recognizes the finger alphabet of Brazilian Sign Language in real time through a webcam and programming.

Theoretical Framework: With this innovation, the future of communication through Libras becomes easier, more accessible and faster. Inclusive communication is being shaped by a convergence of disciplines that seek to facilitate interaction and communication between deaf and non-deaf people.

Method: The method used included publications on assistive technologies and similar technologies that made it possible to develop SignTalk using the Python language and machine learning with thirteen thousand images.

Results and Discussion: The results indicate that in the beta version, SignTalk has shown great inclusive capacity, being a teaching and learning tool of the finger alphabet for the deaf public.

Implications of the Research: This innovation is an inclusive communication tool that uses the guidelines of Sign Language to contribute to the inclusive education of deaf people.

Originality/Value: The study of gestures and machine learning innovates by enabling the system to recognize human hand gestures, returning the corresponding graphical representation of fingers quickly and accurately.
POLITENESS STRATEGY ANALYSIS USED BY TENGGO WICAKSONO IN HIS YOUTUBE CHANNEL
Authors: Suryana Yayan , Zahra Siti Dhea Alfi , Asikin Nida Amalia 
Published: January 2025

This study explores the politeness strategies employed by Tenggo Wicaksono in his Ome TV interactions on YouTube, focusing on their adaptation to informal, cross-cultural digital communication. Using a descriptive qualitative approach, 127 instances of politeness strategies were identified and analyzed based on Brown and Levinson’s framework, revealing a preference for positive politeness strategies (48%), followed by negative politeness (25%), bald on record (22%), and off-record (5%). Positive politeness strategies were prominently used to reduce social distance and build rapport, while negative politeness mitigated impositions in interactions involving greater social distance. The findings emphasize the importance of context and sociological variables, such as power dynamics and rank of imposition, in shaping linguistic choices. This research highlights the adaptability of politeness strategies in digital spaces and recommends further studies on their application across platforms and cultural contexts, providing valuable insights for digital content creators and educators navigating multicultural interactions. Keywords: Politeness strategies; Ome TV; digital communication; cross-cultural interaction; qualitative analysis; pragmatics.
ANALYST OF THE IMPLEMENTATION OF THE INDONESIAN CURRICULUM IN ELEMENTARY SCHOOLS FOR THE 2022-2024 PERIOD
Authors: Nurhasanah Aan , Nugraha Febby Fajar , Sari Mia Zultrianti 
Published: January 2025

This study was conducted to determine how the implementation of the Merdeka Curriculum in elementary school driving schools. This study was conducted using a phenomenological approach because the researcher was interested in studying more deeply the phenomenon of implementing the Merdeka Curriculum in elementary schools, this study was also conducted to determine to what extent the implementation of the Merdeka Curriculum can be implemented in elementary schools. This study was conducted in several driving elementary schools in Kuningan Regency. The informants in this study were teachers, principals and facilitators. Data collection was carried out through in-depth interview techniques. As a basis for the interview instrument, the researcher used a guideline book for the stages of implementing the Merdeka Curriculum compiled by the BSKAP of the Ministry of Education, Culture, Research and Technology in 2022, which consists of 4 stages of implementing the Merdeka Curriculum, namely the initial stage, the developing stage, the ready stage, the advanced stage which consists of 14 aspects. Based on the 14 aspects observed in elementary schools. the results of information processing illustrate that there is 1 aspect, namely the design of the Operational Curriculum of the Education Unit (KOSP), the average school has reached the advanced stage, while the other 13 aspects, the average school is at the initial stage, namely the category still using the example/draft of the Merdeka Curriculum prepared by the Ministry of Education, Research and Technology in the independent teaching platform.Keywords: Implementation; Merdeka Curriculum; Elementary School
Effect of Water Clover Extract (Marsilea crenata Presl.) on the Diameter of the Staphylococcus epidermidis Inhibition Zone
Authors: Lud Waluyo  , Arsya Lingga Datu  , Mohammad Mirza Nuryady  , Erni Yohani Mahtuti  
Published: January 2025

The incidence of acne in Indonesia reaches 85% with an age range of around 15-24 years. The research aims to analyze the effect of water clover extract (Marsilea crenata Presl.) on the inhibition zone of Staphylococcus epidermidis. This type of research is a true experiment with a quantitative approach. The experimental design is The Post Test-Only Control Group Design. The research population was a pure culture of Staphylococcus epidermidis and the sample used was Staphylococcus epidermidis with a density of 1.5 x 10-8. The research method is the well diffusion method. Data were analyzed using one-way analysis of variance (ANOVA). The results of the research were that the concentration of water clover extract (Marsilea crenata Presl.) 25% volume 30µl, 50µl, 75µl, and 100µl had an average diameter of the inhibition zone, namely 6.41 mm, 7.51mm, 8.36 mm, and 9.70 mm. The conclusion of this research is that there is an influence of water clover extract (Marsilea crenata Presl.) on the diameter of the inhibition zone of Staphylococcus epidermidis and the most effective concentration in inhibiting bacterial growth is 25% extract with a volume of 100 µl with an average diameter of the inhibition zone of 9.70 mm.