bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cuidados de enfermagem aos pacientes submetidos à cinecoronariografia e o papel do enfermeiro na retirada do introdutor vascular
Authors: Leão Matheus da Silva , Lima Gabriel de , Araújo Andrey Hudson Interaminense Mendes de 
Published: June 2022

Objetivo: Revisar com base na literatura recente a atuação da enfermagem em relação ao paciente submetido à cinecoronariografia, dando ênfase ao procedimento de retirada de introdutor vascular. Métodos: Trata-se de uma revisão narrativa e intuitiva da literatura, de abordagem qualitativa, utilizando artigos publicados preferencialmente nos últimos 5 anos, disponíveis na íntegra na língua portuguesa ou inglesa, nos bancos de dados da Scientific Eletronic Library Online (Scielo), PubMed e Biblioteca Virtual em Saúde (BVS). Resultados: A enfermagem presta cuidados complexos e essenciais para a manutenção da vida dos pacientes submetidos à cinecoronariografia durante todos os momentos de sua permanência hospitalar. O enfermeiro capacitado e treinado tem autonomia e habilidade para proceder com a retirada do introdutor após procedimento percutâneo na unidade de hemodinâmica. Existem novos dispositivos de oclusão vascular que diminuem o tempo de hospitalização nos casos de punção femural, no entanto, a via radial ainda é associada a menores taxas de intercorrências. O uso da prática baseada em evidência é fundamental na prevenção de iatrogenias. Considerações finais: Existem diversas formas de realizar a retirada do introdutor vascular e adquirir hemostasia. Todas exigem conhecimento e experiência na melhor aplicação dos cuidados e de técnicas de enfermagem. Desta forma, é possível uma recuperação mais rápida, sem aumento dos riscos associados ao procedimento.
Systematic review on the reclamation of areas degraded by mining
Authors: Pereira Júnior Antônio , Freitas Beatriz Galeno , Oliveira Rayssa de Souza , Alves Shelda Silva Ferreira , Sousa Mariana Bastos de , Cabral Estefany Luz , Andrade Leandro da Silva , Silva Marilia Palheta da , Silva Nathalia de Sousa , Pereira Antônio Nilson da Silva , Jesus Edmir dos Santos , Morales Gundisalvo Piratoba , Beltrão Norma Ely Santos 
Published: June 2022

The concern with the economic context and the need for metallic and non-metallic minerals in the current state of world globalization, has caused the abandonment of areas degraded by mineral exploration without any action for their recovery. The objective of this research was to analyze literature about the exploitation of mineral resources for various uses, as well as to seek an answer to the guiding question about the importance of the recovery of these areas after extraction. The method applied was a systematic review with quantitative and qualitative coverage. The data analyzed the occurrence of this type of extraction on a global level. In the Asian continent, China (coal for energy) and Indonesia (sand and gravel for construction) accelerate mineral exploration and this causing environmental impacts such as loss of soil fertility by AMD. In the African continent (Au extraction) in the open air and in an artisanal way, which determines the presence of mercury in water bodies. On the European continent, Poland, the chemical degradation due to the exploitation of iron and brown coal, is accentuated; on the South American continent, the exploitation of lithium in the Atacama Desert, of gold (in an artisanal way), bauxite, clay, sand, agate, iron, among others, present abandoned areas and without any type or proposal for their recovery, which is causing loss of endemic flora and fauna. Thus, it is affirmed that the economy and the advance of technology are not associated with the importance of maintaining the balance of natural ecosystems and do not evaluate, or do so in an incipient way, the importance of the recovery of areas degraded by mineral exploration.
Lomba Kreativitas Membuat Majalah Dinding Untuk Siswa Sekolah Menengah Atas Dengan Tema Sustainable Living By Design
Authors: Sudarwani Margareta Maria 
Published: June 2022

Sampah merupakan salah satu masalah ibu kota yang perlu dipikirkan penanangananya. Siswa-siswa Sekolah Menengah Umum (SMU)/Sekolah Menengah Kejuruan (SMK) sebagai generasi penerus harus terus dilibatkan untuk berkreasi dan berinovasi terhadap keberadaan sampah di lingkungan sehingga di masa depan sampah tidak menjadi beban dari kehidupan. Untuk memaksimalkan keberadaan siswa Sekolah Menengah Umum (SMU) di rumah, maka siswa secara perorangan atau kelompok diberikan peluang untuk berkreasi dengan memanfaatkan material bekas yang ada di rumah menjadi karya majalah dinding kombinasi 2-3 dimensi. Hal ini diharapkan bisa mengisi kesibukan, menghilangkan kejenuhan karena tidak bisa berkumpul dengan teman, namun bisa menghasilkan karya yang bermanfaat. Kegiatan Pengabdian Pada Masyarakat berupa lomba kreativitas membuat majalah dinding, terdiri dari beberapa rangkaian acara yaitu sosialisasi kegiatan dan penyuluhan terkait materi lomba kreativas membuat mading. Sebagai kepedulian terhadap situasi pandemic Covid 19, di dalam majalah dinding juga di tambahkan informasi tentang pentingnya semua masyarakat mentaati protocol kesehatan.
Kata Kunci: kreativitas, lomba, majalah dinding, siswa SMU.
Peninjauan dan Pengukuran Eksisting Bangunan Gereja HKBP Ressort Perumnas Klender
Authors: Tampubolon Sudarno P 
Published: June 2022

Perencanaan/ desain struktur yang matang merupakan hal yang sangat penting dalam mendirikan suatu bangunan. Hal ini menjadi salah satu tujuan dari Pengabdian Kepada Masyarakat (PKM) Fakultas Teknik yang di adakan di Gereja HKBP Ressort Perumnas Klender. Adapun kegiatan yang dilakukan adalah pengukuran dan penggambaran eksisting bangunan Gereja yang telah berdiri, dimana gambar tersebut dapat digunakan oleh pihak Gereja untuk pengembangan dan perbaikan Gereja di masa yang akan datang. Metode yang dilakukan dalam PKM ini adalah dengan melakukan peninjauan lapangan untuk dapat mempersiapkan pengukuran bangunan Gereja, kemudian melakukan pengukuran dan penggambaran sketsa awal dari bangunan Gereja lantai 1 dan 2 secara menyeluruh, sampai pada akhir kegiatannya dilakukan penggambaran 2 dimensi bangunan Gereja sesuai pengukuran yang telah dilakukan di lapangan. Kegiatan PKM ini menghasilkan gambar denah 2 dimensi serta analisa bangunan dari segi arsitektur dan sipil.
Kata Kunci: Pengabdian; pengukuran dan penggambaran; bangunan gereja, perumnas klender.
PENINGKATAN EFISIENSI PRODUKTIVITAS UMKM KERIPIK TEMPE SAGU “BULANKOE” CILEUNGSI KABUPATEN BOGOR
Authors: Samosir Perak 
Published: June 2022

Dampak pandemi Covid-19 tahun 2020 semakin dirasakan pelaku usaha industri kecil di tahun 2021. Salah satunya adalah binaan Pusat Riset dan Pengabdian Masyarakat Institut Teknologi Indonesia (PRPM ITI) yaitu UMKM Keripik Tempe Sagu “Bulankoe” di Cileungsi. Selain adanya persaingan dari usaha serupa sehingga menurunnya konsumen pembeli, masalah utama adalah proses produksi keripik tempe yang masih menggunakan pisau biasa sehingga membutuhkan waktu yang lama untuk pengirisan tempe. Masalah lainnya adalah hasil irisan tempe tidak merata tebal tipis nya. Jika terlalu tipis, irisan tempe akan hancur ketika digoreng dan jika terlalu tebal, irisan tempe kurang kering ketika digoreng sehingga menurunkan jumlah produksi. Dalam rangka mengatasi permasalahan tersebut, Program Studi Teknik Mesin ITI (PS MS ITI) membuat mesin pengiris tempe untuk dihibahkan kepada UMKM Keripik Tempe Sagu “Bulankoe” dan kemudian memberikan pelatihan penggunaan mesin tersebut. Melalui kegiatan pelatihan ini pelaku UMKM mampu mengoperasikan mesin pengiris tempe, waktu pengirisan semakin cepat dengan ketebalan yang diinginkan.
A Platform for Co-Culture of Primary Human Colonic Epithelium With Anaerobic Probiotic Bacteria
Authors: Kim Raehyun , Wang Yuli , Sims Christopher E. , Allbritton Nancy L. 
Published: June 2022

An in vitro platform was designed and optimized for the co-culture of probiotic anaerobic bacteria with a primary human colonic epithelium having a goal of assessing the anti-inflammatory impact of the probiotic bacteria. The device maintained a luminal O2 concentration at &lt;1% while also supporting an oxygenated basal compartment at 10% for at least 72 h. Measurement of the transepithelial resistance of a confluent colonic epithelium showed high monolayer integrity while fluorescence assays demonstrated that the monolayer was comprised primarily of goblet cells and colonocytes, the two major differentiated cell subtypes of the colonic epithelium. High monolayer barrier function and viability were maintained during co-culture of the epithelium with the probiotic obligate anaerobe Anaerobutyricum hallii (A. hallii). Importantly the device supported a static co-culture of microbes and colonic epithelium mimicking the largely static or low flow conditions within the colonic lumen. A model inflamed colonic epithelium was generated by the addition of tumor necrosis factor-α (TNF-α) and lipopolysaccharide (LPS) to the basal and luminal epithelium sides, respectively. Co-culture of A. hallii with the LPS/TNF-α treated intestine diminished IL-8 secretion by ≥40% which could be mimicked by co-culture with the A. hallii metabolite butyrate. In contrast, co-culture of the inflamed epithelium with two strains of lactic acid-producing bacteria, Lactobacillus rhamnosus GG (LGG) and Bifidobacterium adolescentis (B. adolescentis), did not diminish epithelial IL-8 secretion. Co-culture with colonic epithelial cells from different donors demonstrated a consistent anti-inflammatory effect by A. hallii, but distinct responses to co-culture with LGG and B. adolescentis. The demonstrated system offers a simple and easily adopted platform for examining the physiologic impact of alterations in the intestinal epithelium that occur in the presence of probiotic bacteria and their metabolites.
Synthesis of Melatonin Derivatives and the Neuroprotective Effects on Parkinson’s Disease Models of Caenorhabditis elegans
Authors: He Li , Du Jing-Jing , Zhou Jun-Jie , Chen Meng-Ting , Luo Lu , Li Bao-Qiong , Zhang Xiang-Zhi , Ma Wen-Zhe , Ma Ai-Jun , Feng Na 
Published: June 2022

Melatonin (MT) is a hormone with antioxidant activity secreted by the pineal gland in the human brain, which is highly efficient in scavenging free radicals and plays an important role in the neuro-immuno-endocrine system. Emerging evidence showed that MT supplementation was a potential therapeutic strategy for Parkinson’s disease (PD), which inhibits pathways associated with oxidative stress in PD. In this study, we reported a C7-selective olefination of melatonin under rhodium catalysis with the aid of PIII-directing groups and synthesized 10 new melatonin-C7-cinnamic acid derivatives (6a–6j). The antioxidant potential of the compounds was evaluated both by ABTS and ORAC methods. Among these newly synthesized melatonin derivatives, 6a showed significantly higher activity than MT at 10−5 M. In the transgenic Caenorhabditis elegans model of PD, 6a significantly reduces alpha-synuclein aggregation and dopaminergic neuronal damage in nematodes while reducing intracellular ROS levels and recovers behavioral dysfunction induced by dopaminergic neurodegeneration. Further study of the mechanism of action of this compound can provide new therapeutic ideas and treatment strategies for PD.
Lithospheric Thermal Structure in Jinggangshan City: Implications for High Geothermal Background
Authors: Liao Yuzhong , Liu Yanguang , Liu Feng , Wei Shuaichao , Duan Hexiao 
Published: June 2022

Jinggangshan City, which is located in the southwestern part of Jiangxi Province, is rich in hot springs. However, lack of geothermal studies has limited the exploration and utilization of the geothermal resources in this city. This study estimated the terrestrial heat flow in Jinggangshan City through well logging and analyses of rock thermal conductivity and heat production. Based on this and the surrounding geoscience transect and the Crust 1.0 model, this study constructed a one-dimensional lithospheric thermal structure by solving the steady-state heat conduction equation. Furthermore, the deep temperature distribution in Jinggangshan City was obtained to better understand the geodynamic condition of the geothermal resources in this city. The results show that the heat flow in this city is around 83.52 mW/m2, indicating the high heat background for the formation of geothermal resources. According to the lithospheric thermal structure of Jinggangshan City, the mantle contributes more to the terrestrial heat flow (qm/qc &gt; 1) than the crust. The temperature of the Mohorovicic discontinuity (the Moho) is 671.7°C, which is consistent with that below the Tanlu deep fault (620–690°C). Moreover, the calculated depth of the Curie surface (585°C) is 27 km, which is consistent with the Curie isotherm depth estimated from aeromagnetic data. This consistency verifies the validity of the lithospheric thermal structure of Jinggangshan City constructed in this study. In summary, the high heat background plays an important role in the formation of geothermal resources in Jinggangshan City.
Preparation and Thermophysical Properties of Sodium Nitrate/Nanoparticle/Expanded Graphite Composite Heat Storage Material
Authors: Song Wenbing , Lu Yuanwei , Fan Zhansheng , Wu Yuting 
Published: June 2022

As a medium and high temperature heat storage medium, the thermal performance of molten salt plays an important role in the thermal energy storage system. In order to improve the specific heat capacity and thermal conductivity of molten salt, a mechanical dispersion method is used to prepare a shape-stable composite phase change material for thermal energy storage. Nitrate (NaNO3) has a higher phase change latent heat, which was chosen to combined with different nanoparticles (SiO2, SiO2+TiO2) to improve its specific heat capacity, and with expanded graphite (EG) as a carrier matrix to improve thermal conductivity. Through the characterization of its chemical compatibility and thermophysical properties, the results show that the nanoparticles, EG and NaNO3 have good chemical compatibility. Compared to NaNO3, the thermophysical properties of composite (NaNO3:(SiO2+TiO2):EG = 84%:0.1% + 0.9%:15%, mass ratio) was improved obviously. The average specific heat capacity before the phase change increased from 1.45 J/(g·K) to 1.81 J/(g·K), and the average specific heat capacity after the phase change increased from 1.69 J/(g·K) to 2.47 J/(g·K); The thermal conductivity is about 13.9 times higher than that of NaNO3; in the range of 100–380°C, the heat storage density of the composites is about 679.2 kJ/kg 300 thermal stability tests showed that the latent heat of the composites is reduced by 7.4%, and the specific heat capacity before and after the phase change is reduced by 6.1 and 6.0%, respectively. The research can provide a broad application prospects in the field of medium temperature energy storage.
Combination of Acupoints for Alzheimer’s Disease: An Association Rule Analysis
Authors: Wang Yao-Chin , Wu Chieh-Chen , Huang Abel Po-Hao , Hsieh Po-Chun , Kung Woon-Man 
Published: June 2022

BackgroundAlzheimer’s disease (AD) is an ongoing neurological degeneration characterized by amnesia and a decline in cognitive abilities. Hippocampal neurogenesis is the leading cause of AD. Mild cognitive impairment (MCI), a prodromal state of AD, is mainly due to the degradation of neuropsychiatric manifestations. Previous systematic reviews demonstrated that treatment with acupuncture with Chinese herbs is tolerable and effective in improving cognitive function in patients with AD. Our investigation aimed to discover the main acupoint combination for AD management based on a preceding systematic review and meta-analysis of randomized control trials (RCTs).Materials and MethodsOur investigation was executed using association rule analysis, which is a common data mining technique accessible within R. Our study elucidated acupoint locations as binary data from 15 of the included studies using the Apriori algorithm.ResultsThirty-two acupoints were selected from 15 RCTs. The 10 most frequent acupoints were selected. We inspected 503 association rules using the interpreted acupuncture data. The obtained results showed that {SP6, BI10} ≥ {HT7} and {HT7, BI10} ≥ {SP6} were the most associated rules in 15 RCTs.ConclusionThe combination of acupoints ({SP6, BI10} ≥ {HT7} and {HT7, BI10} ≥ {SP6}) can be acknowledged as a core combination for future acupuncture regimens of AD.
Nomograms for Predicting Overall Survival and Cancer-Specific Survival of Patients With Renal Cell Carcinoma and Venous Tumor Thrombus: A Population-Based Study
Authors: Yang Lin , Fu Bin 
Published: June 2022

BackgroundTo provide better prognostic information for patients with renal cell carcinoma (RCC) combined with venous tumor thrombus (VTT). In turn, guide patients’ families and doctors to formulate plans for follow-up treatment and follow-up. We developed nomograms to predict cancer-specific survival (CSS) and overall survival (OS).MethodsA total of 2961 cases were included in this study. Through univariate and multivariate Cox proportional hazard regression analysis, independent risk factors affecting CSS and OS were screened out, and then a nomogram was drawn based on the screened variables.ResultsIndependent risk factors affecting CSS include: tumor size (HR = 1.05), histology (HR = 1.75), grade (HR = 1.94), N staging (HR = 2.06), and M staging (HR = 2.87). The median survival time for CSS was 106 months. Independent risk factors for OS include age (HR = 1.60), tumor size (HR = 1.04), histology (HR = 1.60), grade (HR = 1.68), N staging (HR-1.99), M staging (HR = 2.45). The median survival time for OS is 67 months.ConclusionsThe nomogram based on independent risk factors affecting CSS and OS can well predict the prognosis of renal cell carcinoma with venous tumor thrombus.
Does Change in Physical Activity During the Initial Phase of the COVID-19 Pandemic Predict Psychological Symptoms in Physically Active Adults? A Six-Month Longitudinal Study
Authors: Havnen Audun , Ernstsen Linda 
Published: June 2022

Objectives: The current study aimed to investigate if change in physical activity during the initial phase of the COVID-19 pandemic predicted severity of anxiety and depression symptoms 6 months later in physically active adults.Methods: A total of 855 respondents (32.6% women) completed the Hospital Anxiety and Depression Scale (HADS) at two time points and reported change in physical activity habits in the first 3 months of the COVID-19 lockdown in Norway.Results: Women had higher prevalence rates than men for both anxiety and depression symptoms in the Unchanged, Increased and Decreased physical activity (PA) subgroups. Women and men who reported Increased PA at baseline were associated with increased risk for anxiety symptoms at time 2. Increased PA was associated with higher risk for depression at time 2 for women, but not for men.Conclusion: The results indicate that the COVID-19 pandemic is associated with deterioration in mental health also for physically active adults.
Smoking as a Factor in the Formation of Recurrent Chronic Gastroduodenal Pathology in Adolescents
Authors: Боброва В.И. , Прощенко Ю.И. , Горобец А.О. , Левадная Л.О. 
Published: June 2022

Цель. Установить влияние курения на формирование рецидивирующего течения хронической гастродуоденальной патологии у подростков.Материалы и методы. Под наблюдением находилось 60 подростков 12–17 лет с верифицированной хронической гастродуоденальной патологией (хронический гастрит и хронический дуоденит, язвенная болезнь, язвенная болезнь двенадцатиперстной кишки). Все пациенты прошли исследование на содержание котинина в моче для выявления активных курильщиков. Для верификации хронической гастродуоденальной патологии всем подросткам была выполнена эзофагогастродуоденоскопия с прицельной биопсией слизистой оболочки желудка и двенадцатиперстной кишки. Уровень кислых и нейтральных мукополисахаридов, простагландина Е определяли иммуногистохимическим исследованием.Результаты. У большинства обследованных курящих подростков мы наблюдали выраженную степень воспаления, атрофические и микроциркуляторные изменения слизистой оболочки желудка и двенадцатиперстной кишки, очаговую деструкцию желез. Исследование показало, что у курящих подростков отмечали выраженное снижение показателей преэпителиального и эпителиального уровня защиты слизистого барьера гастродуоденальной зоны.Выводы. Полученные данные указывают на негативное влияние никотина на гистоархитектонику и состояние пилорических и бруннеровых желез слизистой оболочки, а также на функционирование защитного слизистого барьера желудка, способствуя длительному, рецидивирующему течению хронической гастродуоденальной патологии.
Purpose. To establish the effect of smoking on the formation of recurrent chronic gastroduodenal pathology in adolescents.Materials and methods. We observed 60 teenagers aged 12–17 years with verified chronic gastroduodenal pathology (chronic gastritis and chronic duodenitis, ulcer disease, duodenal ulcer). All patients underwent a study of urinary cotinine to identify active smokers. To verify chronic gastroduodenal pathology, all adolescents underwent esophagogastroduodenoscopy with targeted biopsy of the stomach and duodenum mucosa membrane. The level of acidic and neutral mucopolysaccharides, prostaglandin E was determined by immunohistochemical examination.Results. In dominating majority of smoking teenagers we have observed expressed inflammation, atrophic and microcirculatory changes of stomach and duodenal mucosa and focal destruction of glands. Investigation has demonstrated remarkably decreased indexes of supraepithelial and epithelial mucosal protective barrier in gastroduodenal zone in smoking teens.Conclusions. Received data indicate negative influence of nicotine on mucosal architectonics, pyloric and brunner’s glands condition as well as stomach’s mucosal protective barrier functioning which contribute to prolonged and relapsing course of chronic gastroduodenal pathology.
Gastrointestinal Tract Damage in Systemic Connective Tissue Diseases (Juvenile Idiopathic Arthritis, Systemic Lupus Erythematosus) in Childhood
Authors: Сукало А.В. , Строгая Н.В. 
Published: June 2022

В статье представлены данные о частоте и особенностях поражения желудочно-кишечного тракта (ЖКТ) при системных заболеваниях соединительной ткани, в частности при ювенильном идиопатическом артрите (ЮИА) и системной красной волчанке (СКВ). Большинство исследований, посвященных изучению факторов риска, диагностики и лечению поражения гастроинтестинальной системы, проведено на взрослой группе пациентов. В развитии поражения ЖКТ у детей с ревматическими заболеваниями ведущими патогенетическими факторами являются активность заболевания, наличие васкулита и проводимая терапия. Поражение ЖКТ может быть первичным, т. е. являться следствием аутоиммунного процесса, либо возникать вторично на фоне проводимой агрессивной противовоспалительной терапии. В обзоре указаны данные о связи ЮИА и сахарного диабета 1-го типа, а также СКВ и целиакии вследствие развития так называемого синдрома перекреста (overlap-синдром).
The article presents data on the frequency and characteristics of damage of the gastrointestinal tract (GIT) in systemic diseases of the connective tissue, in particular in juvenile idiopathic arthritis (JIA) and systemic lupus erythematosus (SLE). Most of the studies devoted to the study of risk factors, diagnosis and treatment of lesions of the gastrointestinal system were carried out on an adult group of patients. In the development of gastrointestinal lesions in children with rheumatic diseases, the leading pathogenetic factors are the activity of the disease, the presence of vasculitis and ongoing therapy. The lesion of the gastrointestinal tract can be primary, i. e. be a consequence of an autoimmune process, or occur a second time against the background of aggressive anti-inflammatory therapy. The review provides data on the relationship between JIA and type 1 diabetes mellitus, as well as SLE and celiac disease due to the development of the overlap-syndrome.