bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kinetic Model Development of the Oligomerization of High Olefin Containing Hydrocarbon By-products to Clean Engine Fuels on Amberlyst Catalyst
Authors: Bárkányi Ágnes , Varga Tamás , Hancsók Jenő 
Published: May 2022

Nowadays, since the demand for engine fuels is continuously changing, in petroleum refineries, increasing the flexibility of gasoline/middle distillate is still an important issue, e.g. by oligomerizing light olefins (3–6 carbon atoms). The aim of our work was to develop a valid kinetic model based on the extended Eley-Rideal mechanism to describe the oligomerization of the olefin content of light naphtha by fluidized catalytic cracking (FCC) on an ion-exchange resin. Experiments were carried out in a fixed-bed tubular reactor at temperatures of between 80 and 130 °C with liquid hourly space velocities (LHSV) of between 0.5 and 2.0 1/h using Amberlyst® 15 as a catalyst. The oligomerization process was characterized based on the composition of products determined by gas chromatography. The conversion of olefins and the selectivity of the oligomerization reactions forming C8-11 and C12+ hydrocarbons (C8-11 and C12+ selectivity; unit: relative %) were dependent on factors that determine the reactor performance in order to identify the kinetic model parameters. Given that the developed reactor model described the measured data reasonably accurately, it can be used in terms of the optimal design of an industrial oligomerization reactor.
Species composition of dung beetles (Coleoptera: Scarabaeidae: Scarabaeinae) in the coffee plantation of Nilgiri Biosphere Reserve of the Western Ghats, India
Authors: Jayaprakash Subha Babu , Thomas Sabu K. 
Published: May 2022

Analysis of species composition of dung beetles in the shaded coffee plantations of Nilgiri Biosphere Reserve of south Western Ghats revealed a checklist of 38 species. The presence of many endemic species, very primitive rare old world tribe Canthonini represented by the genus Ochicanthon, the first report of Onthophagus lilliputanus and the presence of two (O. truncaticornis and O. discedens) which were deemed as extinct from the natural forests of the Western Ghats) make the dung beetle assemblage in the coffee plantation unusual. Onthophagus lilliputanus and the presence of two species (O. truncaticornis and O. discedens). The study showed species composition of dung beetles in the shaded coffee plantation with a comparatively smaller area had no major differences with the nearby natural forests in the Nilgiri Biosphere Reserve. Higher species richness and presence of some unique species in the coffee plantation belt compared to other agricultural habitats highlights the significance of shaded coffee plantations as an important nested habitat in the forest-agriculture land matrix of the moist Western Ghats.
Population characteristics of louse Columbicola columbae Linn. 1758 (Phthiraptera: Insecta) on pigeons in Uttar Pradesh, India
Authors: Rana Satyapal Singh , Gupta Nidhi , Bhardwaj Sanjay Kumar , Khan Ghazi 
Published: May 2022

Population characteristics of the pigeon louse, Columbicola columbae were recorded on 360 pigeons in the district Meerut, Uttar Pradesh during 2017. Parasitic infestation was 70 per cent with mean intensity of 58.5, with a range of 1-200. The louse exhibited skewed distribution on host body (variance/ mean = 44.5; index of discrepancy = 0.54; exponent of negative binomial = 0.34), however the frequency distribution pattern could not conform to negative binomial model. Sex ratio and adult nymph ratio of the louse were also skewed (M: F = 1: 1.3; A: N = 1: 1.2). Mean monthly prevalence and mean intensity of infestation exhibited significant positive correlation with the environmental temperature and photoperiod but not with relative humidity.
Effect of Addition of Potassium Permanganate (KMnO4) on Shelf Life of Bananas Coated With Chitosan Based Coating
Authors: Meysyaranta Syalistya , Effendy Mohammad , Wardhono Endarto Yudo 
Published: May 2022

The most popular fruit is bananas. The problem bananas face declining quality or preservation of fruit before reaching the consumers. The decline in the quality of post-harvest bananas is generally caused by shrinkage of fruit mass and ripening caused by respiration and the presence of ethylene gas. One of the ways to prevent the decrease in the quality of bananas is by coating the fruit with Chitosan-based edible film. This study aims to determine the effect of adding ethylene absorber (KMnO4) to the coating Chitosan base and the composition of the coating film with the best performance in extending the shelf life of bananas. Edible film Nano Chitosan was synthesized from Sodium tripolyphosphate (TPP) and the addition of Cellulose nanocrystal (CNC) as a stabilizer agent to form a nano-composite to improve the mechanical properties of the edible coating. The method used is to provide a coating of Chitosan, and nano Chitosan with the addition of CNC and KMnO4 applied on bananas. The analysis results showed that the composition of Chitosan-CNC-KMnO4 gave the optimum performance in decline shrinkage of bananas mass with a weight loss value of 4.87% in 5th days had the lowest sugar content value on the 5th day, which was 16%.ABSTRAKBuah yang paling digemari masyarakat salah satunya adalah Pisang. Salah satu problem terkait buah pisang adalah penurunan kualitas atau pengawetan buah pisang sebelum sampai konsumen. Penurunan kualitas buah pisang pasca panen pada umumnya disebabkan oleh penyusutan massa buah dan pematangan sebelum waktunya yang diakibatkan respirasi dan adanya gas Ethylene. Penurunan kualitas buah pisang dapat dihambat dengan melapisi buah dengan coating berbasis Chitosan. Tujuan dari penelitian untuk mengetahui pengaruh penambahan Ethylene absorber (KMnO4) pada coating film berbasiskan Chitosan serta komposisi coating film dengan performa terbaik dalam memperpanjang umur simpan buah pisang. Edible film Chitosan dan nano Chitosan disintesis dari Natrium Tripolyphospate (TPP) serta penambahan Celulose Nano Crystal (CNC) sebagai agen stabilizer sehingga terjadi keadaaan nano-komposit untuk meningkatkan properti mekanis dari edible coating. Metode yang digunakan dengan memberikan coating berbasis Chitosan dan berbasis nano Chitosan dengan penambahan CNC dan KMnO4 pada buah pisang. Hasil analisa menunjukkan bahwa coating dengan komposisi nano Chitosan-CNC-KMnO4 memberikan performa terbaik dalam menghambat penyusutan buah pisang dengan nilai susut bobot 4,87% Dan juga dalam menghambat pematangan, buah pisang memiliki nilai kadar gula terendah, yaitu sebesar 16%.
Relationship between Depression and Antihypertensive Medication Adherence in the Elderly
Authors: DEMİR BARUTCU Canan 
Published: May 2022

Aim: This study was conducted to determine the presence of depression in elderly patients with hypertension and to evaluate its relationship with treatment adherence.
Material and Methods: The sample of this descriptive and correlational study consisted of 334 patients with aged 65 and over which using antihypertensive drugs. Data were collected using the hypertension compliance assessment scale and the geriatric depression scale.
Results: 58.4% of the patients participating in the study were evaluated as incompatible according to the score they got from the hypertension compliance assessment scale. The mean score that the patients got from the compliance scale was found as 7.29 ± 2.65. 39.5% of the patients included in the study were found to be mildly depressed compared to the average score they got from the depression scale. The mean score obtained from the depression scale was found to be 6.70 ± 3.44. As the age of the patients participating in the study increased, it was found that the score which they got from the hypertension compliance assessment scale increased, and there was a weakly positive significant relationship between them (r = 0.113, p = 0.038).
Conclusion: As a result, there is a relationship between treatment compliance and depression levels in the elderly. As the age of elderly patients increases, their level of compliance with treatment decreases and their depressive symptoms increase. Therefore, healthcare professionals should routinely evaluate the symptoms of depression in the elderly with chronic diseases such as hypertension.
Biosynthesis of Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) From Glucose by Escherichia coli Through Butyryl-CoA Formation Driven by Ccr-Emd Combination
Authors: Saito Shu , Imai Ryu , Miyahara Yuki , Nakagawa Mari , Orita Izumi , Tsuge Takeharu , Fukui Toshiaki 
Published: May 2022

Poly[(R)-3-hydroxybutyrate-co-(R)-3-hydroxyhexanoate] [P(3HB-co-3HHx)] is a practical kind of bacterial polyhydroxyalkanoates (PHAs). A previous study has established an artificial pathway for the biosynthesis of P(3HB-co-3HHx) from structurally unrelated sugars in Ralstonia eutropha, in which crotonyl-CoA carboxylase/reductase (Ccr) and ethylmalonyl-CoA decarboxylase (Emd) are a key combination for generation of butyryl-CoA and the following chain elongation. This study focused on the installation of the artificial pathway into Escherichia coli. The recombinant strain of E. coli JM109 harboring 11 heterologous genes including Ccr and Emd produced P(3HB-co-3HHx) composed of 14 mol% 3HHx with 41 wt% of dry cellular weight from glucose. Further investigations revealed that the C6 monomer (R)-3HHx-CoA was not supplied by (R)-specific reduction of 3-oxohexanoyl-CoA but by (R)-specific hydration of 2-hexenoyl-CoA formed through reverse β-oxidation after the elongation from C4 to C6. While contribution of the reverse β-oxidation to the conversion of the C4 intermediates was very limited, crotonyl-CoA, a precursor of butyryl-CoA, was generated by dehydration of (R)-3HB-CoA. Several modifications previously reported for enhancement of bioproduction in E. coli were examined for the copolyester synthesis. Elimination of the global regulator Cra or PdhR as well as the block of acetate formation resulted in poor PHA synthesis. The strain lacking RNase G accumulated more PHA but with almost no 3HHx unit. Introduction of the phosphite oxidation system for regeneration of NADPH led to copolyester synthesis with the higher cellular content and higher 3HHx composition by two-stage cultivation with phosphite than those in the absence of phosphite.
Implementation of Perforated Concentric Ring Walls Considerably Improves Gas-Liquid Mass Transfer of Shaken Bioreactors
Authors: Hansen Sven , Gumprecht Andreas , Micheel Linda , Hennemann Hans-Georg , Enzmann Franziska , Blümke Wilfried 
Published: May 2022

Since their first use in the 1930s, shake flasks have been a widely used bioreactor type for screening and process development due to a number of advantages. However, the limited gas-liquid mass transfer capacities—resulting from practical operation limits regarding shaking frequency and filling volumes—are a major drawback. The common way to increase the gas-liquid mass transfer in shake flasks with the implementation of baffles is generally not recommended as it comes along with several severe disadvantages. Thus, a new design principle for shaken bioreactors that aims for improving the gas-liquid mass transfer without losing the positive characteristics of unbaffled shake flasks is introduced. The flasks consist of cylindrical glass vessels with implemented perforated concentric ring walls. The ring walls improve the gas-liquid mass transfer via the formation of additional liquid films on both of its sides, whereas the perforations allow for mixing between the compartments. Sulfite oxidation experiments revealed over 200% higher maximum oxygen transfer capacities (OTRmax) compared to conventional shake flasks. In batch cultivations of Escherichia coli BL21 in mineral media, unlimited growth until glucose depletion and oxygen transfer rates (OTR) of up to 138 mmol/L/h instead of an oxygen limitation at 57 mmol/L/h as in normal shake flasks under comparable conditions could be achieved. Even overflow metabolism could be prevented due to sufficient oxygen supply without the use of unconventional shaking conditions or oxygen enrichment. Therefore, we believe that the new perforated ring flask principle has a high potential to considerably improve biotechnological screening and process development steps.
Recent Publication Trends in Radiotherapy and Male Infertility over Two Decades: A Scientometric Analysis
Authors: Roychoudhury Shubhadeep , Das Anandan , Panner Selvam Manesh Kumar , Chakraborty Saptaparna , Slama Petr , Sikka Suresh C. , Kesari Kavindra Kumar 
Published: May 2022

Radiotherapy, a popular cancer management procedure, negatively impacts reproductive health particularly by reducing the fertility potential. The purpose of this study was to analyze the research trend in radiotherapy associated with male infertility over the past 20 years (2000-May 2021). SCOPUS database was used to retrieve relevant scientometric data (publication per year, affiliation, journals, countries, type of document and area of research) for different subgenres of radiotherapy and male infertility. A total of 275 articles were published related to radiotherapy and male infertility, with the United States being the most dominant country in research output in this field. Radiotherapy and male infertility research have shown positive growth over the last two decades. In-depth analysis revealed that publications (n) related to radiotherapy and male infertility research mainly focused its impact on semen parameters (n = 155) and fertility preservation techniques (n = 169). Our scientometric results highlight a limited research focus on the field of radiotherapy and its impact on male reproductive hormones. Furthermore, a significant lack of research was noticed in the area of omics and male reproductive organs linked to radiotherapy. Substantial research is warranted to further decipher the effect of radiotherapy, at molecular level, leading to male infertility.
Associations of Blautia Genus With Early-Life Events and Later Phenotype in the NutriHS
Authors: Freitas Renata G. Borges de Oliveira Nascimento , Vasques Ana Carolina J. , Fernandes Gabriel da Rocha , Ribeiro Francieli B. , Solar Isabela , Barbosa Marina G. , Pititto Bianca de Almeida- , Geloneze Bruno , Ferreira Sandra Roberta G. 
Published: May 2022

IntroductionEarly-life events are associated with the risk of obesity and comorbidities later in life. The gut microbiota—whose composition is influenced by genetics and environmental factors—could be involved. Since the microbiota affects metabolism and fat storage, early-life insults could contribute to the occurrence of obesity driven, in part, by microbiota composition. We examined associations of gut bacteria with early-life events, nutritional status, and body composition in the Nutritionist’s Health Study (NutriHS).MethodsA cross-sectional study of 114 female participants examining early-life data, body composition, and biological samples was conducted. Fecal microbiota structure was determined targeting the V4 region of the 16S rRNA gene. Principal coordinates analysis (PCoA) and permutational multivariate analysis of variance (PERMANOVA) were used to test the impact of variables on microbial diversity. Profiles were identified using the Jensen-Shannon divergence matrix and Calinski–Harabasz index. Differential abundance between the categories of exclusive breastfeeding duration and nutritional status was tested using DESeq2.ResultsIn the sample [median age 28 years and body mass index (BMI) 24.5 kg/m2], 2 microbiota profiles driven by the Blautia or Prevotella genus were identified. An estimated 9.1% of the variation was explained by the profiles (p &lt; 0.001), 2.1% by nutritional status (p = 0.004), and 1.8% by exclusive breastfeeding (p = 0.012). The proportion of participants with BMI &lt;25 kg/m2 and who were breastfed for at least 6 months was higher in the Blautia profile (p &lt; 0.05).ConclusionFindings in a Blautia-driven profile of healthy women reinforce that early-life events play a role in defining gut microbiota composition, confirming the importance of exclusive breastfeeding for infant gut colonization in establishing a protective profile against adiposity-related outcomes in adulthood.
Radiomics and Machine Learning for Detecting Scar Tissue on CT Delayed Enhancement Imaging
Authors: O'Brien Hugh , Williams Michelle C. , Rajani Ronak , Niederer Steven 
Published: May 2022

BackgroundDelayed enhancement CT (CT-DE) has been evaluated as a tool for the detection of myocardial scar and compares well to the gold standard of MRI with late gadolinium enhancement (MRI-LGE). Prior work has established that high performance can be achieved with manual reading; however, few studies have looked at quantitative measures to differentiate scar and healthy myocardium on CT-DE or automated analysis.MethodsEighteen patients with clinically indicated MRI-LGE were recruited for CT-DE at multiple 80 and 100 kV post contrast imaging. Left ventricle segmentation was performed on both imaging modalities, along with scar segmentation on MRI-LGE. Segmentations were registered together and scar regions were estimated on CT-DE. 93 radiomic features were calculated and analysed for their ability to differentiate between scarred and non-scarred myocardium regions. Machine learning (ML) classifiers were trained using the strongest set of radiomic features to classify segments containing scar on CT-DE. Features and classifiers were compared across both tube voltages and combined-energy images.ResultsThere were 59 and 51 statistically significant features in the 80 and 100 kV images respectively. Combined-energy imaging increased this to 63 with more features having area under the curve (AUC) above 0.9. The 10 highest AUC features for each image were used in the ML classifiers. The 100 kV images produced the best ML classifier, a support vector machine with an AUC of 0.88 (95% CI 0.87–0.90). Comparable performance was achieved with both the 80 kV and combined-energy images.ConclusionsCT-DE can be quantitatively analyzed using radiomic feature calculations. These features may be suitable for ML classification techniques to prospectively identify AHA segments with performance comparable to previously reported manual reading. Future work on larger CT-DE datasets is warranted to establish optimum imaging parameters and features.
Live Online Education Efficiency Mediators From the Actor Network Theory Perspective
Authors: Czahajda Radoslaw , Čairović Neda , Černko Mitja 
Published: May 2022

PurposeThe purpose of this research was to explore the conceptual network of live online education efficiency from the Actor Network Theory perspective to reveal different aspects influencing the quality of online training less accounted for in previous research.MethodologyActor Network Theory was used to analyse the qualitative feedback from 100 live online education sessions. Responses from 90 educators and 556 participants were coded into enablers and inhibitors of education quality and further clustered into different actors that might mediate learning success.FindingsThe key finding of this research is a visual representation of the complex network of actors potentially affecting live online education quality, revealing the interplay of non-human aspects (e.g., hardware, software, session design, and descriptions), as well as human elements (participants and their expectations, educators and their emotional reactions attributed to different actors of the network, organisers, and external mentors/experts).LimitationsThe piloting qualitative research was conducted within the framework of one educational event, where participants opted in voluntarily to attend and participate in the study. It is a specific educational context different from workplace training and other non-formal education.Practical ImplicationsLearning and development practitioners can find 10 recommendations designed to support the instructional design and delivery of their (online) sessions based on the collective experiences of the study participants and authors.Originality/valueIt is the first research in the field of live online education, acknowledging and mapping the role of multiple actors posited to play an influential role in the overall quality. It also calls for a transition from “content-focused and controlling” to “contextually-aware and responsive” educator in future research.
Characterization of lncRNA Profiles of Plasma-Derived Exosomes From Type 1 Diabetes Mellitus
Authors: Pang Haipeng , Fan Wenqi , Shi Xiajie , Li Jiaqi , Wang Yimeng , Luo Shuoming , Lin Jian , Huang Gan , Li Xia , Xie Zhiguo , Zhou Zhiguang 
Published: May 2022

BackgroundsExosomes contain several types of transcripts, including long non-coding RNAs (lncRNAs), and have been shown to exert important effects in human diseases. However, the roles of exosomal lncRNAs in type 1 diabetes mellitus (T1DM) have not been well investigated. In the present study, we characterized the plasma-derived exosomal lncRNAs expression profiles of T1DM and predict their potential function in the pathogenesis of T1DM.Material and MethodsExosomal lncRNA expression profiles were detected by Illumina Hiseq platform (T1DM subjects N=10; age-, sex- matched Control subjects N=10). Six exosomal lncRNAs were selected to validate their expression level by using quantitative real-time PCR (qRT-PCR) (T1DM subjects N=30; age-, sex- matched Control subjects N=30). Bioinformatics analysis approaches were carried out to explore the potential biological function of differentially expressed lncRNAs.ResultsA total of 162 differentially expressed exosomal lncRNAs were identified in T1DM patients compared with control subjects, among which 77 up-regulated and 85 down-regulated. The expression level of the selected six lncRNAs didn’t show significant difference in the following qRT-PCR analysis. Gene Ontology analysis enriched terms such as activation of phospholipase D activity, neuronal cell body membrane, and calcium sensitive guanylate cyclase activator activity for cis-acting genes of lncRNAs, and metal ion binding for trans-acting genes. The most enriched Kyoto Encyclopedia of Genes and Genomes pathways for the lncRNAs were associated with oxidative phosphorylation and Parkinson’s disease for cis-acting genes, and pathways in cancer as well as focal adhesion for trans-acting genes.ConclusionsThis study characterized the lncRNA profiles of plasma-derived exosomes from T1DM for the first time and these results highlighted the potential role of exosomal lncRNAs in T1DM pathogenesis. A better understanding of exosomal lncRNA profiling will provide novel insights into its molecular mechanisms.