bluuebunny/crossref_metadata_2025_split huggingface dataset:
3D-printed vertebral body for anterior spinal reconstruction in patients with thoracolumbar spinal tumors
Authors: Zhou Hua , Liu Shanshan , Li Zhehuang , Liu Xiaoguang , Dang Lei , Li Yan , Li Zihe , Hu Panpan , Wang Ben , Wei Feng , Liu Zhongjun 
Published: March 2022

OBJECTIVE
A 3D-printed vertebral prosthesis can be used to reconstruct a bone defect more precisely because of its tailored shape, with its innermost porous structure inducing bone ingrowth. The aim of this study was to evaluate the clinical outcomes of using a 3D-printed artificial vertebral body for spinal reconstruction after en bloc resection of thoracolumbar tumors.

METHODS
This was a retrospective analysis of 23 consecutive patients who underwent surgical treatment for thoracolumbar tumors at our hospital. En bloc resection was performed in all cases, based on the Weinstein-Boriani-Biagini surgical staging system, and anterior reconstruction was performed using a 3D-printed artificial vertebral body. Prosthesis subsidence, fusion status, and instrumentation-related complications were evaluated. Stability of the anterior reconstruction method was evaluated by CT, and CT Hounsfield unit (HU) values were measured to evaluate fusion status.

RESULTS
The median follow-up was 37 (range 24–58) months. A customized 3D-printed artificial vertebral body was used in 10 patients, with an off-the-shelf 3D-printed artificial vertebral body used in the other 13 patients. The artificial vertebral body was implanted anteriorly in 5 patients and posteriorly in 18 patients. The overall fusion rate was 87.0%. The average prosthesis subsidence at the final follow-up was 1.60 ± 1.79 mm. Instrument failure occurred in 2 patients, both of whom had substantial subsidence (8.47 and 3.69 mm, respectively). At 3 months, 6 months, and 1 year postoperatively, the mean CT HU values within the artificial vertebral body were 1930 ± 294, 1997 ± 336, and 1994 ± 257, respectively, with each of these values being significantly higher than the immediate postoperative value of 1744 ± 321 (p < 0.05).

CONCLUSIONS
The use of a 3D-printed artificial vertebral body for anterior reconstruction after en bloc resection of the thoracolumbar spinal tumor may be a feasible and reliable option. The low incidence of prosthesis subsidence of 3D-printed endoprostheses can provide good stability instantly. Measurement of HU values with CT is a valuable method to evaluate the osseointegration at the bone-metal interface of a 3D-printed vertebral prosthesis.
African Development Bank: Impact on economic growth
Authors: Matveevsky Sergey S. 
Published: March 2022

The article examines the impact of the African Development Bank (AfDB) on economic growth. The main activity of the Bank is connected with the projects that create new assets and directly affect the economy.
The large amount of total assets of all Development Banks in the world, the significant annual amount of financing they provide determine their importance for the global economy. The author concludes that economic growth is associated with the use of five strategic programs: &quot;Feed Africa&quot;, &quot;Give energy and power to Africa&quot;, &quot;Develop the industrialization of Africa&quot;, &quot;Integrate Africa&quot; and &quot;Ensure an improvement in the quality of life for Africans&quot;.
The Bank uses strategies for cooperation with African countries, planning and implementing projects under these strategic programs. As a result, new jobs are being created, agricultural productivity is increasing, and the infrastructure of African countries is developing.
The effectiveness of the AfDB&apos;s activities is related to the multi-level evaluation system it uses, which allows assessing the dynamics of development in Africa as a whole, its contribution to the successful implementation of all planned and accepted operations, the quality of these operations and the effectiveness of the Bank as an organization. This system allows qualitatively and quantitatively evaluate the completed projects, the achievement of the set economic and social goals, provides information for the preparation and implementation of corrective control actions. The AfDB links the inclusiveness of economic growth with the emergence of positive consequences for a significant part of the population of African countries with the growth of GDP (an increase in the share of GDP per citizen).
«ХАОС» ТА «СКЛАДНІСТЬ» ЯК СИСТЕМАТИЧНІ ІНСТРУМЕНТИ ДЛЯ ВИВЧЕННЯ СУЧАСНОГО ІНФОРМАЦІЙНОГО ПРОСТОРУ
Authors: Zrazhevska N. 
Published: March 2022

<div><p><strong><em>The purpose</em></strong><em> of the article is to update the application of such concepts as «chaos» and «complexity» for analyzing processes in the modern information space and to investigate the problems of chaos in the field of media messages, which is considered as a natural stage in the emancipation of consumers and media producers.</em></p></div><p><strong><em>Research methods</em></strong><em>. In the analysis of this topic, the </em><em>study </em><em>use the idea and hypothesis of the theory of nonlinearity in the study of mass communication processes</em><em>, as well as </em><em>postmodern and post structural chaology in the understanding of the modern infosphere.</em></p><p><strong><em>Results.</em></strong><em> We argue that the study of random and unpredictable processes in media can be configured using a methodological approach that uses «chaos» and «complexity» as systematic tools to explore the modern information space. The chaos in the media is also provoked by the shaping of the modern agenda, since the new communication paradigm offers more fragmented, concise, dramatic information, which in turn calls into question the sense of its significance. The article poses the following problems: how and why the selection system works, distortions in media messages, why no effective tool has yet been found to resist chaos in the media, and why it is impossible in principle to overcome chaotic processes both in the socio-cultural space and directly in the plane of media culture. The article examines chaos as an element of self-organization of media communication, as a result of which there is an impetus to new processes of development of the information space. We cannot deny the fact that chaos in the modern infosphere has gradually become an integral, </em><em>component </em><em>part of reality, since media culture has become a total force of modernity.</em></p><p><strong><em>Novelty</em></strong><em> of the article lies in the fact that the analysis of chaotic elements in a message makes it possible to understand the nature of chaos in media communication, its role in the formation of everyday practices and, in general, in mass communications. Since the manipulative and propaganda side of mass communication is increasingly becoming the norm and value of new media, and manipulation and propaganda are intensified by the very chaos of events and messages about them, then in the analysis of the modern information space, attention should be focused on understanding and managing these processes.</em></p><p><strong><em>The practical significance</em></strong><em> of the research results lies in the fact that they can be used in the process of analysing specific media messages in order to identify communicative noises or accidental </em><em>(</em><em>or</em><em> </em><em>intentional</em><em>)</em><em> connotations.</em></p><strong><em>Key words:</em></strong><em> post-non-classical paradigm, chaos, complexity, unpredictability, media, info space, entropy, post-truth.</em>
Aplicação da periodização do treinamento desportivo em modalidades esportivas de combate
Authors: Vidal Rafael Gemin 
Published: March 2022

O presente estudo teve por objetivo investigar a aplicação da periodização por professores e mestres de modalidades esportivas de combate. A amostra do tipo não probabilística intencional foi composta por 14 professores e mestres das modalidades de Jiu-Jitsu, Judô, Kung Fu, Taekwondo, Muay Thai, Kickboxing e Karatê atuantes na região. Para atingir os objetivos propostos a pesquisa utilizou um questionário, que investigou o processo de preparação física, técnica, tática e psicológica dos atletas. De acordo com os resultados obtidos, podemos identificar que a maior parte dos treinadores possui formação acadêmica em Educação Física. Embora todos tenham afirmado fazer algum tipo de planejamento para a temporada de seus atletas, há uma preferência por conhecimentos específicos de cada modalidade. Podemos concluir que a escolha e construção dos modelos de periodização de treinamento, utilizados pelos participantes estudados, reflete o conhecimento prático, experiências do modelo artesanal e no conhecimento empírico, sendo os treinadores os principais responsáveis pela preparação e planejamento do treinamento de seus atletas. Embora não tenham citado nenhuma literatura, quando observado a forma com que planejam a temporada, podemos identificar as semelhanças a configurações previstas pelo Modelo Clássico de Matveev e o Modelo de Estado de Rendimento Prolongado de Bompa.
The Effect of a Pandemic on Computed Tomography Pulmonary Angiography Results and Utilize in the Emergency Department
Authors: KÜÇÜKCERAN Kadir , AYRANCI Mustafa Kürşat 
Published: March 2022

Objective: The incidence of pulmonary embolism (PE) increases with COVID-19. With the pandemic, changes occur in the utilization of computed tomography pulmonary angiography (CTPA), which we use in the diagnosis of PE. In our study, we investigated the impact of the pandemic on the utilized and result of CTPA.
Methods: Patients over the age of 18 who applied to the emergency department between 01.03.2019 and 28.02.2021 and underwent CTPA was included in this retrospective study. Patients were separated to two groups based on the date of the first case. CTPA result and Polymerase chain reaction (PCR) positivity status were recorded. Data were compared between groups.
Results: While 757(1.022%) out of 74,063 patients underwent CTPA in the pre-pandemic period, 649(1.430%) out of 45,397 patients underwent CTPA in the during-pandemic period. The PE rate in patients who underwent CTPA in the during-pandemic period was statistically significantly
higher compared to the pre-pandemic period (pre-pandemic: 89(11.9%), during-pandemic: 122(19%), p
Unraveling Structural Phase Transformation by Simultaneously Determining the Lattice Constants and Mismatch Angle in VO2/Al2O3 Epitaxial Thin Films
Authors: Liu Yichao , Wang Cangmin , Huang Wenyu , Wang Shaoting , Qiu Huaili , Ge Weifeng , Chen Meixia , Zhang Hui , Gu Yueliang , Zhang Xingmin , Li Xiaolong , Gao Xingyu , Yang Yuanjun 
Published: March 2022

As a prototype of a strongly correlated electron system, bulk vanadium dioxide (VO2) exhibits a large and reversible metal–insulator transition (MIT) near 340 K, concomitantly accompanied by a monoclinic–rutile structural phase transformation (SPT). In this study, we systematically investigated the SPT across the MIT in a (010)-VO2/(0001)-Al2O3 epitaxial thin film by simultaneously determining three lattice constants (a, b, and c) and the mismatch angle (Δβ) using high-resolution X-ray diffraction. The lattice constants a, b, and c were approximately 5.723, 4.521, and 5.393 Å, respectively, at room temperature, and the mismatch angle was approximately 122.02°. As the temperature increased, the lattice constants and mismatch angle did not change significantly until the temperature reached the MIT point. Then, a, b, and c suddenly increased to approximately 5.689 Å, 4.538 Å, and 5.411 Å, respectively, and retained this value up to nearly 90°C. However, the mismatch angle first slightly increased and then sharply decreased to 122.00°. Additionally, the lattice constants and mismatch angle were almost reproducible with decreasing temperature, except for hysteresis in the MIT region. These results verify that VO2 undergoes an MIT, simultaneously accompanied by SPT, in thicker films with small strain and weak substrate constraints, analogous to bulk VO2. This was further confirmed by in-situ varying-temperature Raman characterization. These findings provide insights into the SPT and reveal an angular parameter for judging the SPT in VO2 systems.
Diagnostic Management of Oncogenic HPV Cervical Infections: The Field Experience in Wuxi, China
Authors: Liu Yang , Yin Yongxiang , Zhang Yi , Lin Luling , Zhao Min , Chen Qi 
Published: March 2022

IntroductionA liquid-based cytology test was introduced for cervical cancer screening in the 2000s worldwide. However, the concordance of diagnostic findings between the liquid-based cytology test and cervical biopsy has not been fully investigated, especially the overall failure rate on the diagnosis of cervical cancer and high-grade squamous intraepithelial lesion (HSIL) by cytology testing. The aim of this retrospective study was to investigate the concordance between ThinPrep cytology and histology test in the diagnosis of cervical cancer and HSIL in HPV-positive women.MethodsThinPrep cytology test was performed in 2,472 HPV-positive women. Out of 2,472 HPV-positive women, the cervical biopsy was concurrently performed in 1,533 women. Data on the HPV type and the diagnostic findings of the ThinPrep cytology test and cervical biopsy were collected from our hospital electronic database. The concordance of diagnostic findings between cytology and histology was compared.ResultsThe rate of agreement in the diagnosis of the low-grade squamous intraepithelial lesion (LSIL) or HSIL between cervical biopsy and ThinPrep cytology test was 58 or 49%. The overall false negative rate in the diagnosis of cervical cancer and HSIL by ThinPrep cytology test was 6%. However, when considering the total number of HPV-positive women diagnosed with cervical cancer (n = 36) and HSIL (n = 117) by cervical biopsy, we found that a significant number of HPV-positive women with cervical cancer (n = 12, 33%), or women with HSIL (n = 77, 66%) were failed to be diagnosed by the ThinPrep cytology test. These HPV-positive women were either diagnosed with cervical infection or ASCUS, or LSIL.DiscussionOur data demonstrated that in order to ensure an accurate diagnosis, an immediate cervical biopsy in women with cervical infection or ASCUS or LSIL should be strongly recommended in clinical practice.
Drinking Natural Mineral Water Maintains Bone Health in Young Rats With Metabolic Acidosis
Authors: Tan Yao , Xu Anwei , Qiu Zhiqun , Wang Lingqiao , Wang Jia , Luo Jiaohua , Zeng Hui , Jin Huidong , Wang Yushu , Xue Jing , Huang Yujing , Shu Weiqun 
Published: March 2022

IntroductionMetabolic acidosis affects bone health. It remains unclear whether drinking natural mineral water is better for maintaining bone health in the youth with metabolic acidosis.Materials and MethodsSixty young female rats (3-weeks-old) were randomly divided into three groups and drank purified water (PW, as control), bicarbonate-rich natural mineral water (Bic-NMW), or sulfate-rich natural mineral water (Sul-NMW), which, respectively, contained calcium (0.17, 155, and 175 mg/L), bicarbonate (0.1360, and 139 mg/L) and sulfate (0, 35.6, and 532 mg/L), for 16 weeks. In the last 3 weeks, metabolic acidosis was induced in 10 rats per group by adding NH4Cl (0.28 mM) to drinking water. The rats' blood, urine, and femur were collected for assessing acid-base status, calcium metabolism, bone microstructure, and strength. The difference between the three groups was determined using one-way ANOVA followed by the Student–Newman–Keuls test or Dunnett's T3 test.ResultsCompared with the PW rats, the Bic-NMW rats and the Sul-NMW rats had less urine net acid excretion (−1.51, 0.20 vs. 10.77, EQ/L), higher bone mineral density (442.50, 407.49 vs. 373.28, mg/mm3), growth cartilage width (271.83, 283.83 vs. 233.27, μm) and cortical trabecular area (9.33, 9.55 vs. 5.05, mm2), and smaller cortical marrow cavity area (5.40, 5.49 vs. 7.27, mm2) in the femur (P &lt; 0.05). Besides, the Bic-NMW rats had less serum calcium (2.53 vs. 2.68, mmol/L) and C-terminal cross-linked telopeptide of type-I collagen (1.35 vs. 1.93, ng/mL), and higher serum calcitonin (0.61 vs. 0.39, μg/L), femoral trabecular thickness (0.10 vs. 0.09, μm), bone volume/total volume (0.42 vs. 0.34, %), cortical bone area (15.91 vs. 12.80, mm2), and ultimate stress (35.12 vs. 29.32, MPa) (P &lt; 0.05). The Sul-NMW rats had more osteoclasts (22.50 vs. 11.54, cells/field) (P &lt; 0.05).ConclusionsDrinking natural mineral water, especially bicarbonate-rich natural mineral water, is effective in improving bone health in young rats with metabolic acidosis. These benefits include maintaining bone mineral density, and improving bone microstructure and biomechanical properties via moderating metabolic acidosis.
Personalized Dietary Recommendations Based on Lipid-Related Genetic Variants: A Systematic Review
Authors: Pérez-Beltrán Yolanda E. , Rivera-Iñiguez Ingrid , Gonzalez-Becerra Karina , Pérez-Naitoh Naomi , Tovar Juscelino , Sáyago-Ayerdi Sonia G. , Mendivil Edgar J. 
Published: March 2022

BackgroundObesity and dyslipidemias are risk factors for developing cardiovascular diseases, the leading causes of morbidity and mortality worldwide. The pathogenesis of these diseases involves environmental factors, such as nutrition, but other aspects like genetic polymorphisms confer susceptibility to developing obesity and dyslipidemias. In this sense, nutrigenetics is being used to study the influence of genetic variations on the circulating lipid responses promoted by certain nutrients or foods to provide specific dietary strategies considering the genetic factors in personalized nutrition interventions.ObjectiveTo identify throughout a systematic review the potential nutrigenetic recommendations that demonstrate a strong interaction between gene-diet and circulating lipid variations.MethodsThis systematic review used the PRISMA-Protocol for manuscript research and preparation using PubMed and ScienceDirect databases. Human studies published in English from January 2010 to December 2020 were included. The main results were outcomes related to gene-diet interactions and plasmatic lipids variation.ResultsAbout 1,110 articles were identified, but only 38 were considered to fulfill the inclusion criteria established based on the reported data. The acquired information was organized based on gene-diet interaction with nutrients and components of the diet and dietary recommendation generated by each interaction: gene-diet interaction with dietary fats, carbohydrates or dietary fiber, gene-diet interaction with nutraceutical or dietary supplementation, and gene-diet interaction with proteins.ConclusionFindings included in this systematic review indicated that a certain percentage of dietary macronutrients, the consumption of specific amounts of polyunsaturated or monounsaturated fatty acids, as well as the ingestion of nutraceuticals or dietary supplements could be considered as potential strategies for the development of a wide range of nutrigenetic interventions since they have a direct impact on the blood levels of lipids. In this way, specific recommendations were identified as potential tools in developing precision diets and highlighted the importance of personalized nutrition. These recommendations may serve as a possible strategy to implement as dietary tools for the preventive treatment and control alterations in lipid metabolism.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021248816, identifier [CRD42021248816].
MYB2 Is Important for Tapetal PCD and Pollen Development by Directly Activating Protease Expression in Arabidopsis
Authors: Guo Xiaorui , Li Lihong , Liu Xiatong , Zhang Chong , Yao Xiaoyun , Xun Zhili , Zhao Zhijing , Yan Wenwen , Zou Yirong , Liu Di , Li Hui , Lu Hai 
Published: March 2022

Tapetal programmed cell death (PCD) is a complex biological process that plays an important role in pollen formation and reproduction. Here, we identified the MYB2 transcription factor expressed in the tapetum from stage 5 to stage 11 that was essential for tapetal PCD and pollen development in Arabidopsis thaliana. Downregulation of MYB2 retarded tapetal degeneration, produced defective pollen, and decreased pollen vitality. EMSA and transcriptional activation analysis revealed that MYB2 acted as an upstream activator and directly regulated expression of the proteases CEP1 and βVPE. The expression of these proteases was lower in the buds of the myb2 mutant. Overexpression of either/both CEP1 or/and βVPE proteases partially recover pollen vitality in the myb2 background. Taken together, our results revealed that MYB2 regulates tapetal PCD and pollen development by directly activating expression of the proteases CEP1 and βVPE. Thus, a transcription factor/proteases regulatory and activated cascade was established for tapetal PCD during another development in Arabidopsis thaliana. Highlight: MYB2 is involved in tapetal PCD and pollen development by directly regulating expression of the protease CEP1 and βVPE and establishes a transcription factor/proteases regulatory and activated cascade.
Hyperandrogenic Dysfunction in Young Women: Diagnosis and Treatment Options in Gynecological Practice
Authors: Кириллова Е.Н. 
Published: March 2022

Синдром гиперандрогении – симптомокомплекс, который характеризуется избыточными эффектами андрогенов в женском организме и включает в себя разнородные по патогенезу заболевания, которые могут проявляться сходной клинической картиной. Частота распространения гиперандрогенных состояний, по данным разных авторов, в пубертатном периоде составляет 6–10%. Актуальность этой проблемы для гинекологов заключается в том, что гиперандрогенные состояния сопровождаются нарушениями менструальной функции, приводят к бесплодию и невынашиванию беременности. В то же время в период становления менструальной функции менструальный цикл может быть ановуляторным, а умеренный гирсутизм и акне – физиологическим явлением. Это часто затрудняет диагностику и приводит к задержке начала лечения. В статье представлены общие сведения о наиболее частых состояниях, сопровождаемых гиперандрогенией: синдроме поликистозных яичников, неклассической форме врожденной дисфункции коры надпочечников, гипоталамическом синдроме пубертатного периода. В статье обсуждены особенности клинической картины, принципов обследования, критерии диагностики и дифференциальной диагностики гиперандрогенных состояний у подростков, сформулированы принципы ведения юных пациенток с риском формирования синдрома поликистозных яичников.
Hyperandrogenism is a complex of symptoms that is characterized by excessive effects of androgens in the female body and includes diseases that are heterogeneous in pathogenesis, which can manifest in a similar clinical signs. The frequency of distribution of hyperandrogenic states according to different authors in the puberty is 6–10%. The relevance of this problem for gynecologists is associated with hyperandrogenism is accompanied by menstrual dysfunction, lead to infertility and miscarriage. At the same time, during the formation of menstrual function and the menstrual cycle can be anovulatory, and moderate hirsutism and acne can be a physiological phenomenon. These factors contribute to difficulties in the diagnosis and delay the start of treatment. The article provides general information about the most common conditions caused by hyperandrogenism:polycystic ovary syndrome, nonclassic congenital adrenal hyperplasia, hypothalamic syndrome of puberty. The article discusses the features of the clinical signs, principles of examinations, diagnostic criteria and differential diagnosis of hyperandrogenic conditions in adolescents, formulates the principles of management of young patients with a risk of polycystic ovary syndrome.