bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of different surgical routes on pregnancy outcome of history-indicated cervical cerclage
Authors: QIN FENG , ZHOU Wei , YANG Yong , CHI Yugang , LIU Bao , CHEN Gongli 
Published: October 2022

Abstract
Objective
To study the guiding significance of medical history on laparoscopic and vaginal cervical cerclage in the treatment of cervical incompetence and its influence on pregnancy outcome.
Methods
A total of 53 cases of cervical cerclage by laparoscopy before pregnancy (laparoscopic group) and 73 cases of preventive cervical cerclage by vagina (vaginal group) at 12–14 weeks of pregnancy were collected. Multivariate logistic regression analysis was performed on the influencing factors of delivery gestational weeks. To further compare the difference of delivery gestational weeks after cervical cerclage between laparoscopic group and vaginal group with high and low risk levels.
Results
The number of previous uterine cavity operations in laparoscopic group was more than that in vaginal group, the hospitalization days and operation time were longer than those in vaginal group, the delivery rate of cesarean section was higher than that in vaginal group, but the total hospitalization times were less than that in vaginal group(P < 0.05). The rate of delivery before 34 weeks of pregnancy and the incidence of premature rupture of membranes or premature labor in laparoscopic group were lower than those in vaginal group(P < 0.05). In the vaginal group, the increased number of prior PTB or STL and the history of cervical cerclage failure will increase the risk of premature delivery before 34 weeks of pregnancy. There was no significant difference in the influence of laparoscopic history on delivery before 34 weeks of pregnancy(P > 0.05). According to the risk level, in the high-risk group the delivery rate of laparoscopic group at gestational weeks < 37 weeks, < 34 weeks and < 28 weeks was lower than that of vaginal group.
Conclusion
Laparoscopic cervical cerclage is more effective in preventing premature delivery before 34 weeks of gestation, and its influence on delivery gestational weeks is not affected by related medical history. For high-risk patients, laparoscopic cervical cerclage is more effective than vaginal cervical cerclage in preventing extremely preterm 28 weeks ago, premature delivery 34 weeks ago and preterm delivery 37 weeks ago. Therefore, laparoscopic cervical cerclage is preferred for patients with high-risk medical history. However, laparoscopic cervical cerclage significantly increases the cesarean section rate, and the advantages and disadvantages of retaining laparoscopic cervical cerclage in situ still need further follow-up and research.
A cross-circulatory platform for monitoring innate responses in lung grafts
Authors: Matthieu Glorion , Florentina Pascale , Jérôme Estephan , Maxime Huriet , Carla Gouin , Céline Urien , Fany Blanc , Julie Rivière , Christophe Richard , Valérie Gelin , Julien De Wolf , Morgan Le Guen , Antoine Magnan , Antoine Roux , Isabelle Schwartz-Cornil , Edouard Sage 
Published: October 2022

Abstract
Lung transplantation is the only curative option of end-stage chronic respiratory diseases. However the survival rate is only about 50% at 5 years. Whereas experimental evidences support that innate allo-responses impact on the clinical outcome, the knowledge of the involved mechanisms is limited. Here, we evaluate a cross-circulatory platform for monitoring the early recruitment and activation of immune cells in an extracorporeal donor lung by coupling blood perfusion to cell mapping with a fluorescent marker in the pig, a commonly-used species for lung transplantation. The perfusing pig cells were easily detectable in lung cell suspensions, in broncho-alveolar lavages and in different areas of lung sections, indicating infiltration of the organ. Myeloid cells (granulocytes and monocytic cells) were the dominantly recruited subsets. Between 6 and 10 h of perfusion, recruited monocytic cells presented a strong upregulation of MHC class II and CD80/86 expression, whereas alveolar macrophages and donor monocytic cells showed no significant modulation of expression. Altogether the cross-circulation model permits to monitor the initial encounter between perfusing cells and lung graft, in an easy, rapid, and controllable manner, for generating robust information on innate response and testing targeted therapies for improvement of lung transplantation outcome.
Assessment of the Quantity and Quality of Harvested Rainwater in Igah Communities of Kogi State, North West Nigeria
Authors: Usman Victor O. , Ezenwaji Emmanuel E. , Ayatu Usman Ojonugwa , Azuoko George-Best , Akakuru Obinna C. 
Published: October 2022

Abstract
] 1 , Ayatu O. Usman[0000-0002-6039-5468] 2 , George-Best Azuoko*[0000-0002-8836-3062] 2 and Obinna C. Akakuru[0000-This study assessed the quantity and quality of harvested rainwater in Igah communities of Kogi state, Nigeria. Questionnaires were used in data collection, interview and secondary data sources. Stratified random sampling was employed in the sampling of the respondents. 395 copies of questionnaire were determined using Taro Yammane and administered, while 372 of them were completely returned. Principal Component Analysis (PCA) was employed to collapse the various variables responsible for the quantity of rainwater consumed into few underlying dimensions and the rainwater samples into significant orthogonal components. After the PCA, Principal Component Regression (PCR) analysis was used to express the relationship between the quantity of rainwater supplied and the four isolated components of the factors responsible for the quantity of rainwater in the area. Statistical analysis revealed that the mean rainwater consumption per person per day of 8.2 litres is far below the WHO recommended standard. Results also showed that all the physico-chemical parameters analyzed were below the WHO (2017) and NSDWQ (2007) permissible limit for drinking water standard. Again, total coliform count were far above the WHO (2017) drinking water specification of 0cfu/100ml but fell within the 10cfu/100ml permissible limit of NSDWQ (2007) and hence treatment is needed in terms of total coliform. Analysis of Water Poverty Index (WPI) showed low level of water poverty in the area. We recommend further investigation into water scarcity situation in the area and proper treatment of rainwater before consumption to avoid the incidence of Water, Sanitation and Hygiene (WASH) related diseases.
Direct displacement-based design of hysteretic bracings for retrofitting of reinforced concrete buildings
Authors: Monti Giorgio , Rabi Raihan Rahmat , Vailati Marco 
Published: October 2022

Abstract
In this study, a direct displacement-based method is proposed for the design of hysteretic dissipative bracings to be applied to gravity-load-designed (GLD) reinforced concrete (RC) frames. The direct, i.e., non-iterative, design procedure aims at limiting the interstorey drifts of the GLD frame to prevent damage in the existing columns, thanks to the added stiffness and damping of the bracings. The method is based on a simplified yet accurate representation of the braced frame, through a so-called stick model, whose elements stiffness and damping are obtained by equivalent linearization of each braced storey. The method allows obtaining an optimal design of the bracing system at each storey, both in terms of stiffness and damping. The design method efficiency has been validated by comparing the performance of three GLD RC frames retrofitted with bracing systems designed with two other methods available in the literature.
Post-cardiac surgery fungal mediastinitis : clinical features, pathogens and outcome
Authors: HARIRI Geoffroy , GENOUD Mathieu , BRUCKERT Vincent , CHOSIDOW Samuel , GUEROT Emmanuel , KIMMOUN Antoine , NESSELER Nicolas , BESNIER Emmanuel , DAVIAUD Fabrice , LAGIER David , IMBAULT Julien , GRIMALDI David , BOUGLÉ Adrien , MONGARDON Nicolas 
Published: October 2022

Abstract
Objectives
The occurrence of mediastinitis after cardiac surgery remains a rare and severe complication associated with poor outcomes. Whereas bacterial mediastinitis have been largely described, little is known about their fungal etiologies. We report incidence, characteristics, and outcome of post-cardiac surgery fungal mediastinitis.
Methods
Multicenter retrospective study among 10 Intensive Care Units (ICU) in France and Belgium, of proven cases of fungal mediastinitis after cardiac surgery (2009–2019).
Results
73688 cardiac surgery procedures were reviewed, and of those, 40 patients developed fungal mediastinitis. Among them, five were supported with left ventricular assist device and five with veno-arterial ExtraCorporeal Membrane Oxygenation before initial surgery. Twelve patients received prior heart transplantation. Interval between initial surgery and mediastinitis was 38 [17–61] days. Only half of the patients showed local signs of infection. Septic shock was uncommon at diagnosis (12.5%). Forty-three fungal strains were identified: Candida spp (34 patients), Trichosporon spp (5 patients) and Aspergillus spp (4 patients). Hospital mortality was 58%. Survivors were younger (59 [43–65] vs 65 [60–73] yo; p = 0.013), had lower Body Mass Index (24 [20–26] vs 30 [24.5–32.7] kg/m2; p = 0.028) and lower Simplified Acute Physiology Score II score at ICU admission (37 [28–40] vs 54 [34–61]; p = 0.012).
Conclusion
Fungal mediastinitis is a very rare complication after cardiac surgery, associated with a high mortality rate. This entity should be suspected in patients with a smoldering infectious postoperative course, especially those supported with short or long-term cardiac devices, or following heart transplantation.
Chronic Comorbidities and Cervical Cancer Screening adherence in the Korean Population using KHNANES
Authors: Chuck Kumban Walter , hong seri , Lee Yunhwan 
Published: October 2022

Abstract
Purpose
To investigate the cervical cancer screening rates in women with comorbidities – obesity, diabetes, and hypertension in the Korean Population.
Methods
Data of 2,972 people came from the Korean National Health and Nutrition Examination Survey (KNHANES) data 2019. Cancer-free women 30 years old and over were included. Recommended and ever cervical cancer screening rates were compared in participants with and without comorbidities. Comorbidities involving obesity were measured using body mass index in kilograms (BMI ≥ 30kg/m2), The presence of hypertension were measured by complete measurement of diastolic and systolic blood pressures while diabetes were defined based on people who had been diagnosed with diabetes by a physician and had received treatment for diabetes using insulin or other medication and those with fasting blood glucose of ≥ 126mg/dl. Baseline characteristics and cervical cancer screening rates were calculated using weighted frequencies and multivariable regression at 95% confidence interval in both participants.
Results
Ever and recommended cervical screening rates were significantly lower in diabetic patients P < 0.009 and p < 0.001 respectively than in those without diabetes. Recommended screening rate in hypertensive participants was lower, p < 0.036 compared to those without hypertension. Obese patients received lower screening rates, p < 0.013 compared with the non-obese participants.
Conclusion
Comorbidities including diabetes and obesity were less likely to have ever and recommended screening compared with those without diabetes and obesity. Greater efforts need to be made by physicians in high-risk groups to increase cervical cancer screening rates and to achieve parity.
Outcomes of EGFR tyrosine kinase inhibitors and immune checkpoint inhibitors for advanced EGFR-mutated non-small cell lung cancer
Authors: Isono Taisuke , Hasemi Jiro , Hasegawa Airi , Nishida Takashi , Hosoda Chiaki , Kawate Eriko , Kobayashi Yoichi , Ishiguro Takashi , Kagiyama Naho , Kurashima Kazuyoshi , Yanagisawa Tsutomu , Takayanagi Noboru 
Published: October 2022

Abstract
Purpose No clinical trial has compared osimertinib with afatinib. We reviewed clinical data of patients with epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) to identify predictive factors for clinical outcome of first-line EGFR tyrosine kinase inhibitors (TKIs), efficacy and safety of several EGFR-TKIs, and efficacy of immune checkpoint inhibitors (ICIs).
Methods We retrospectively studied 170 patients with EGFR-mutated NSCLC who received first-line EGFR-TKIs from January 1, 2011 to March 31, 2021.
Results Programmed cell death ligand-1 (PD-L1) tumor proportion score (TPS) was available in 66 patients, of whom 14, 25, and 27 had PD-L1 TPS ≥50%, 1-49%, and <1%, respectively. Twenty-four patients received ICIs after EGFR-TKIs. Objective response rate (ORR) and median progression-free survival (PFS) and overall survival (OS) with EGFR-TKIs were 65.3% and 9.1 and 31.4 months, respectively. By multivariate analysis, osimertinib was associated with favorable ORR and median PFS but not with median OS, whereas ICI treatment was associated with favorable median OS. Osimertinib caused less diarrhea, stomatitis, and liver injury. Pneumonitis and neutropenia (mostly grade <2) were more frequent with osimertinib. ORR and median PFS and OS of ICIs were 25.0%, 2.3 months, and not reached (NR), respectively. Particularly, ICIs were more effective in patients with PD-L1 TPS ≥50% than 1-49% or <1% (ORR, 66.7 vs. 12.5 vs. 0.0%; median PFS, 14.3 vs. 3.4 vs. 1.2 months; median OS, NR vs. NR vs. 14.8 months).
Conclusion Osimertinib was more effective and less frequently caused severe adverse events. Patients treated with ICIs had better prognosis.
Design and Simulation of Piezoresistance Temperature Sensor for Electric Vehicle Battery Monitoring System
Authors: Rathnakannan K. , Parasuraman R. , VanajaRanjan P. , S Hosimin Thilagar 
Published: October 2022

Abstract

This paper discusses the design and simulation of a piezo resistance temperature sensor. The sensor was connected according to Wheatstone bridge configuration. The temperature sensor The COMSOL Multiphysics software was used for this study. With a 1µm piezo resistor of the graphene layer and an optimised doping profile of 1016 cm− 3, the simulated sensitivity is 24.90 mV/oC over a temperature range of -90oC to 90oC. The simulated results reveal that the sensitivity significantly depends on the piezo resistor layer thickness, combination of the materials, shape of the diaphragm, and the size of the diaphragm. With the low thermal mass and excellent sensitivity, the suggested temperature sensors based on graphene can be employed in battery health monitoring systems.
Feasibility, Safety and Effectiveness of Robot-assisted Retroperitoneal Partial Adrenalectomy with a new robotic surgical system: A Prospective, Single-Center, Single- Arm Clinical Study
Authors: Xu Weifeng , Dong Jie , Ji Ruoyu , Liu Guanghua , Zhou Jingmin , Wang Huizhen , Ji Zhigang , Cui Liang 
Published: October 2022

AbstractObjectives:To evaluate the feasibility, safety and efficacy of the newly developed KD-SR-01®robotic system for retroperitoneal partial adrenalectomy.Subjects and Methods:We prospectively enrolled patients with benign adrenal mass undergoing KD-SR-01®robot-assisted partial adrenalectomy in our institution from November 2020 to May 2022. Surgeries were performed via a retroperitoneal approach using the KD-SR-01®robotic system. The baseline, perioperative and short-term follow-up data were prospectively collected. A descriptive statistical analysis was performed.Results:A total of 23 patients were enrolled, including nine (39.1%) patients with hormone-active tumors.All patients received partial adrenalectomy via the retroperitoneal approach without conversions to other procedures. The median operative time was 86.5 minutes (interquartile range (IQR), 60.0-112.5) and the median estimated blood loss was 50 mL (range, 20-400). Three (13.0%) patients developed Clavien-Dindo grade I-II postoperative complications. The median postoperative stay was 4.0 days (IQR, 3.0-5.0). All surgical margins were negative. The short-term follow-up demonstrated complete or partial clinical and biochemical success as well as absence of imaging recurrence in all patients with hormone-active tumors.Conclusions: Initial results illustrate that the KD-SR-01®robotic system is safe, feasible and effective for the surgical management of benign adrenal tumors.
EFL/ESL Teachers’ Perception of Students with Learning Disabilities in Bangladesh
Authors: Islam Rabiul 
Published: October 2022

Abstract

The number of students with special education needs is not clearly categorized in Bangladesh. Students with visible and perceptible physical and psychological disabilities may ask for supports and facilities that are required for their educational progress. But students with learning disabilities such as dyslexia, dysgraphia, dyscalculia, ADHD do not get such services in Bangladesh. This paper focuses on the English language teachers in Bangladesh teaching at the pre-primary, primary, and secondary level to understand their perceptions of learning disabilities and intervention strategies. It also asks how the teachers would accommodate any students with learning disabilities in their classrooms. A blend of quantitative and qualitive data has been extracted in the process through in-person and virtual interviews with the teachers. Twelve teachers participated voluntarily in this study and shared their insight based on their personal experiences. Most of them claimed to have heard about learning disabilities but were not able to explain the term and relate with their experience. They expressed a positive inclination to accommodate children with any type of disabilities in their classrooms regardless of their pedagogical or infrastructural capacity. Further studies are required in this field since current literature largely exclude students with learning disabilities in Bangladesh.
Biochemical and functional characterization of rice straw for alternative industrial uses
Authors: Malik Kamla , Sharma Ajay , karthik Dandu Hari , RANI VIJAYA , Malik Anurag , Sangwan Punesh , Bhatia Tanvi , Rani Sunita , sindhu meena 
Published: October 2022

Abstract
As an agricultural state, Haryana (India) produces about six million metric tons (mt) of rice straw every year from rice cultivation. Currently, rice straw is either burned or ploughed into the field without being turned into a functional product. Burning of paddy straw pollutes the air, results in green house gas emission, particulate matter (2.5 and 10 µm) emission, considerable losses on the properties of the soil, soil nutrients, organic matter, productivity and biodiversity, and on and off-farm humans and animals’ health. The biochemically and functionally specified potential for optimal alternative use of the rice straw of 13 most widely produced rice varieties from Haryana’s eastern and western agro-climate zones was undertaken. Pusa-1401 variety had the highest cellulose (46.55%) and silica content (13.70%), while Pusa-1718 had hemicellulose (28.25%) and lignin (11.60%), respectively. Maximum nitrogen (0.81%), phosphorus (0.32%) and potassium (2.78%) were found in rice variety Pusa-1509, Pusa-1401 and Rice-6129. The findings seemed to be statistically significant (p < 0.05). The biochemical profiles of rice straw cultivars were classified into distinct structural groups (C-H alkalanes, O-H alcohol, C = O, C–H alkanes) based on the FTIR spectrum in order to find the best alternative possibilities for bioethanol and compost production. According to the study, these rice straw varieties could be used to make lucrative industrial products.
Weakening of western disturbances in response to polar sea ice melt in climate model simulations
Authors: Chandra Varunesh , Sandeep Sukumaran , Hunt Kieran M R 
Published: October 2022

Abstract
The response of low-latitude weather and climate to polar sea ice melt is not well understood. In this study, we run a suite of coupled and uncoupled simulations using the Community Earth System Model to investigate the effects of polar sea ice melt on western disturbance (WD) activity over the Indian subcontinent. In the coupled model simulation, the albedo of the sea ice is reduced in such a way that the increased absorption of the solar radiation would melt the sea ice. Further, the monthly climatology of sea surface temperature (SST) and sea ice concentrations (SIC) from the coupled model runs are used to force the Community Atmospheric Model (CAM5) at higher resolution (50 km). WD vortices in the CAM5 simulations are tracked using a Lagrangian tracking algorithm. Our analyses reveal that WD activity is reduced in the CAM5 simulations forced with the SST and SIC from the sea ice melt experiment. We show that this is because the subtropical jet becomes more baroclinically stable and shifts equatorward in response to the polar sea ice melt. The weakening and widening of the subtropical jet is consistent with the predicted changes to thermal wind and upper-tropospheric meridional temperature gradient in response to the polar sea ice melt.
Monitoring environmental indicators by coupling remote sensing and weather data: applications to the Brazilian biomes
Authors: Teixeira Antônio , Leivas Janice , Takemura Celina , Bayma Gustavo , Garçon Edlene , Sousa Inajá , Farias Franzone , Silva Cesar 
Published: October 2022

Abstract
The SAFER (Simple Algorithm for Evapotranspiration Retrieving) algorithm and the radiation use efficiency (RUE) model were coupled to test large-scale environmental indicators in the Brazilian biomes. The MODIS MOD13Q1 reflectance product and weather data were used along the year 2016. The analyzed biomes were Amazon (AM), Caatinga (CT), Cerrado (CE), Pantanal (PT), Atlantic Forest (AF), and Pampa (PP). Significant differences on precipitation (P), actual evapotranspiration (ET), and biomass production (BIO) yielded differences on water balance (WB = P - ET) and water productivity (WP = ET/BIO). The highest WB and WP along the year were for the wettest AM, AF, and PP biomes, when compared with the driest CT. Precipitation (P) distribution along the year affected the magnitude of the evaporative fraction (ETf), i.e, the ratio of ET to reference evapotranspiration (ET0), however there was a gap between ETf and WB, what can be related to the time needed for recovering the good conditions of soil moisture levels after rainfalls. For some biomes, BIO was related to the levels of absorbed photosynthetically active radiation (PARabs), which depends on the leaf area and soil cover (AM, AF, and PP), while for others BIO followed the soil moisture levels, represented by ETf (CT, CE, and PT). The large-scale modelling presented suitability for monitoring environmental parameters at a 250-m spatial and 16-day spatial and temporal resolutions, with great potential to subsidize public policies regarding the management and conservation of the natural resources, with possibility for replication of the methods in other countries.