bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychotropic Medication Use and Psychiatric Disorders During the COVID-19 Pandemic Among Danish Children, Adolescents, and Young Adults
Authors: Bliddal Mette , Rasmussen Lotte , Andersen Jacob Harbo , Jensen Peter Bjødstrup , Pottegård Anton , Munk-Olsen Trine , Kildegaard Helene , Wesselhoeft Rikke 
Published: December 2022

ImportanceThe direct and indirect implications of the COVID-19 pandemic have been associated with the mental health of children and adolescents, but it is uncertain whether these implications have been associated with changes in prescribing and diagnosis patterns.ObjectiveTo examine psychotropic medication use and rates of psychiatric disorders in Danish children, adolescents, and young adults during the COVID-19 pandemic.Design, Setting, and ParticipantsThis population-based, descriptive register-based cohort study included all Danish individuals aged 5 to 24 years from January 1, 2017, until June 30, 2022.Main Outcomes and MeasuresRates of filled prescriptions of psychotropic medications, including antipsychotics, anxiolytics, hypnotics, sedatives, antidepressants, and psychostimulants, and all inpatient and outpatient contacts with mental and behavioral disorders. Rates of new (incident) and total (prevalent) psychotropic medication use and psychiatric diagnoses were estimated. Rate ratios (RRs) were assessed between observed and expected numbers of incident psychotropic medication use or psychiatric diagnoses from March 2020 to June 30, 2022, comparing observed numbers with expected numbers predicted from the modeled prepandemic trend.ResultsThe study identified 108 840 (58 856 female individuals [54%]; median [IQR] age, 18 [14-22] years) incident psychotropic medication users. From March 2020 (first national lockdown) to June 2022, the rate of incident users of any psychotropic medication showed a relative increase of 18% (RR, 1.18; CI, 1.17-1.20) compared with expected numbers, which was primarily associated with an increase among those aged 12 to 17 years of 37% (RR, 1.37; 95% CI, 1.34-1.41). Similarly, there was an overall relative increase of incident psychiatric disorders of 5% (incidence rate, 1.05; CI, 1.04-1.07) (incident cases, 114 048 [58 708 female individuals (51%)]), which was associated with an increase in hyperkinetic disorders (RR, 1.13; CI, 1.09-1.18) and anxiety disorders (RR, 1.04; CI, 1.02-1.06). Prevalence patterns showed similar trends of an overall increase in psychotropic medication use and psychiatric disorders. One of 3 new users of an individual drug group had filled a prescription for a drug from another psychotropic medication group within the prior 6 months.Conclusions and RelevanceThe results of this cohort study suggest that Danish youths experienced an increase in rates of psychotropic treatment and psychiatric disorder diagnoses during the COVID-19 pandemic, which was most pronounced among those aged 12 to 17 years. The increase was observed for children and adolescents with and without a psychiatric history within the last 5 years.
Dethiobacteraceae fam. nov.
Authors: Sorokin Dimitry Y. , Merkel Alexander Y. 
Published: December 2022

Abstract

De.thi'o.bac.ter.a.ce.a.e. N.L. masc. n.
Dethiobacter
, the type genus of the family; L. fem. pl. n. suff.
-aceae
, ending to denote a family; N.L. fem. pl. n.
Dethiobacteraceae
, the family of the genus
Dethiobacter
.

Firmicutes D / Dethiobacteria / Dethiobacterales / Dethiobacteraceae fam. nov.

The family
Dethiobacteraceae
includes obligately anaerobic, moderately salt‐tolerant, and obligately alkaliphilic bacteria able to grow chemolithoautotrophically by elemental sulfur disproportionation and fixing CO
2
by the Wood–Ljungdahl pathway. The two strains currently known in pure culture are both isolated from saline soda lakes. H
2
can serve as an additional electron donor for sulfur and thiosulfate reduction. The family consists of a single genus
Dethiobacter
with the type species
Dethiobacter alkaliphilus
.

DNA G
+
C content (%): 48.3–48.5
(genomes of two isolates).

Type genus
:
Dethiobacter
Sorokin et al. 2008, VL123.
Methanotorris
Authors: Mukhopadhyay Biswarup , Dodsworth Jeremy A. , Whitman William B. 
Published: December 2022

Abstract

Me.tha.no.tor' ris. N.L. neut. n.
methanum
, methane; from French masc. n.
méthyle
; from Chem. N.L. neut. suff.
‐ane
; N.L. pref.
methano‐
, pertaining to methane; L. masc. n.
torris
, a brand, firebrand; N.L. masc. n.
Methanotorris
, the methane‐producer at fiery temperatures.

Methanobacteriota_A / Methanococci / Methanococcales / Methanococcaceae / Methanotorris

Regular to irregular cocci, 0.8–1.8 μm in diameter. Nonmotile with a few thin and long flagella‐like filaments. Obligately anaerobic. Extremely thermophilic or hyperthermophilic (temperature optimum: 75–88°C). pH optimum 5.7–6.7. NaCl required for growth; optimal concentration 1.8–2.4% (w/v). Obligate methanogens; H
2
and, in some of the species, formate, but not acetate, dimethylsulfide, ethanol,
d
/
l
‐lactate, methanol, methylamines, and pyruvate, serve as the electron donors. Autotrophic growth in mineral medium. Complex carbon sources and selenium are neither required nor stimulatory. All species can use ammonium as nitrogen source, and one of these uses nitrate and N
2
. Isolated from deep‐sea and shallow marine hydrothermal systems.

DNA G + C content (mol%)
: 32.3–32.4 (genome analysis).

Type species
:
Methanotorris igneus
Whitman 2001, VL85 (basonym:
Methanococcus igneus
Burggraf et al. 1990, VL35).
Alteribacillus
Authors: Amoozegar Mohammad Ali , Mehrshad Maliheh 
Published: December 2022

Abstract

Al.te.ri.ba.cil'lus. L. masc. adj.
alter
, another, the other; L. masc. n.
bacillus
, a rod and also a bacterial generic name (
Bacillus
); N.L. masc. n.
Alteribacillus
, another
Bacillus
.

Bacillota / Bacilli / Bacillales / Bacillaceae / Alteribacillus

The genus
Alteribacillus
contains endospore‐forming rod‐shaped cells that stain Gram‐positive. The genus is classified within the family
Bacillaceae
, order
Bacillales
, and in the class
Bacilli
. The cells are strictly aerobic; moderately halophilic and mesophilic microorganism, growing in media containing 0.5–24% (w/v) NaCl at temperatures in the range of 20–50°C with optimum growth at 3–10% (w/v) NaCl and 35–40°C. cells grow optimally at pH 7.0–8.5. Chemoorganotrophic, and a number of sugars and organic acids used as sole carbon and energy sources. Acid is produced from different sugars. Catalase‐ and oxidase‐positive. The major polar lipids are phosphatidylglycerol and diphosphatidylglycerol. MK‐7 is the major respiratory quinone. The DNA G + C content of the members of this genus ranges from 37.0 to 41.0 mol%. Phylogenetically related to the genera
Bacillus, Filobacillus
, and
Virgibacillus
in the family
Bacillaceae
. Currently, the genus includes four species.
Alteribacillus bidgolensis
is the type species of the genus that was isolated from a water sample of the Aran‐Bidgol hypersaline lake in Iran.

DNA G + C content (mol%)
: 37.0–41.0 (HPLC).

Type species
:
Alteribacillus bidgolensis
Didari et al. 2012
VP
.
Salsuginibacillus
Authors: Ventosa Antonio 
Published: December 2022

Abstract

Sal.su.gin'i.ba.cil.lus. L. fem. n.
salsugo ‐inis
, salted water; L. masc. n.
bacillus
, rod; N.L. masc. n.
Salsuginibacillus
, a rod living in salted water.

Bacillota / Bacilli / Bacillales / Bacillaceae / Salsuginibacillus

The genus
Salsuginibacillus
is classified within the family
Bacillaceae
, order
Bacillales
, and in the phylum
Bacillota
(
Firmicutes
). The cells are Gram‐stain‐positive, endospore‐forming rods. Motile or nonmotile, occurring singly or in pairs. Ellipsoidal endospores are present in a central or subterminal position. Catalase‐positive and oxidase‐negative. Nitrate is reduced to nitrite. Halophilic, not able to grow in the absence of NaCl. Alkaliphilic or alkali tolerant. Chemoorganotrophic. Strictly aerobic. Optimal growth at 10–19% (w/v) NaCl, pH 8.5–9.0, and 37°C. The cell‐wall peptidoglycan type is A1γ with
meso
‐diaminopimelic acid. The major cellular fatty acids are anteiso‐C
15:0
and anteiso‐C
17:0
. The major polar lipids are diphosphatidylglycerol, phosphatidylglycerol, phosphatidylethanolamine, phospholipids, and glycolipids. The predominant respiratory quinone is MK‐7. The DNA G + C content is 44.7–46.4 mol%. Currently, the genus includes two species:
Salsuginibacillus kocurii
(type species of the genus) and
Salsuginibacillus halophilus
. The species were isolated from sediments of soda lakes in Inner Mongolia, China.

DNA G + C content (mol%)
: between 44.7 and 46.4.

Type species
:
Salsuginibacillus kocurii
Carrasco et al. 2007
VP
.
Sediminibacillus
Authors: Ventosa Antonio 
Published: December 2022

Abstract

se.di'mi.ni.ba.cil.lus. L. neut. n.
sedimen ‐inis
, sediment; L. masc. n.
bacillus
, a small rod; N.L. masc. n.
Sediminibacillus
, a rod living in sediment.

Bacillota / Bacilli / Bacillales / Bacillaceae / Sediminibacillus

The genus
Sediminibacillus
is classified within the family
Bacillaceae
, order
Bacillales
, and in the phylum
Bacillota
(
Firmicutes
). The cells are Gram‐stain‐positive, rod shaped, and occur singly, in pairs, or in short chains. Motile. Endospores may be formed terminally in swollen sporangia or not be observed. Cells are aerobic or facultatively anaerobic. Catalase‐ and oxidase‐positive. Nitrate may or may not be reduced to nitrite. Moderately halophilic. Optimal growth at 5.0–7.5% (w/v) NaCl, pH 7.5–8.0, and 30–37°C. The cell‐wall peptidoglycan type is A1γ with
meso
‐diaminopimelic acid. The major cellular fatty acids are anteiso‐C
15:0
and anteiso‐C
17:0
. The major polar lipids are diphosphatidylglycerol, phosphatidylglycerol, and an unidentified glycolipid. The predominant respiratory quinone is MK‐7. The DNA G + C content is 41.3–44.1 mol%. Currently, the genus includes three species:
Sediminibacillus halophilus
(type species of the genus),
Sediminibacillus albus
, and
Sediminibacillus terrae
. The strains of these species were isolated from sediments of hypersaline lakes in China or nonsaline soils.

DNA G + C content (mol%)
: between 41.3 and 44.1.

Type species
:
Sediminibacillus halophilus
Carrasco et al. 2008
VP
.
Mobilicoccus
Authors: Hamada Moriyuki 
Published: December 2022

Abstract

Mo.bi.li.coc'cus. L. masc./fem. adj.
mobilis
, mobile; N.L. masc. n.
coccus
, (from Gr. masc. n.
kokkos
, grain, seed) coccus; N.L. masc. n.
Mobilicoccus
, a mobile coccus.

Actinomycetota / Actinomycetia / Dermatophilales / Dermatophilaceae / Mobilicoccus

The genus
Mobilicoccus
is Gram‐stain‐positive, facultatively anaerobic, and mesophilic actinobacteria. Cells are coccus shaped, non‐endospore‐forming, and motile with peritrichous flagella. Catalase‐positive and oxidase‐negative. The cell‐wall peptidoglycan is of the A1γ type. The predominant isoprenoid quinone is MK‐8(H
2
), and the principal polar lipids are diphosphatidylglycerol, phosphatidylglycerol, and phosphatidylinositol. The major cellular fatty acids consist of monounsaturated and saturated straight‐chain fatty acids, with C
17:1
and C
15:0
as the major components. The G + C content of the genomic DNA is 69.8–71.9 mol%. Phylogenetically, the genus belongs to the family
Dermatophilaceae
within the order
Dermatophilales
. Currently, the genus contains two validly published species, namely,
Mobilicoccus pelagius
and
Mobilicoccus caccae
. The type species of the genus is
M. pelagius
, and the type strain is Aji5‐31
T
, which was isolated from the intestinal tract of a fish collected from the beach on the coast of Tokyo Bay, Japan. The type strain of the second species,
M. caccae
, is YIM 101593
T
, which was isolated from the feces of a primate living in Yunnan Wild Animal Park in Yunnan, China.

DNA G + C content (mol%)
: 69.8–71.9 (genome, HPLC).

Type species
:
Mobilicoccus pelagius
Hamada et al. 2010, VL139.
Methanofervidicoccus
Authors: Sakai Sanae 
Published: December 2022

Abstract

Me.tha.no.fer.vi.di.coc'cus. N.L. neut. n.
methanum
, methane; N.L. pref.
methano
‐, pertaining to methane; L. masc. adj.
fervidus
, hot; N.L. masc. n. ‘
coccus
’, (from Gr. masc. n.
kokkos
) a grain or berry and, in biology, a spherical cell; N.L. masc. n.
Methanofervidicoccus
, a coccus producing methane at high temperatures.

Euryarchaeota / Methanococci / Methanococcales / Methanococcaceae / Methanofervidicoccus

The genus
Methanofervidicoccus
includes obligately anaerobic, thermophilic, and hydrogenotrophic methanogens producing methane from H
2
/CO
2
for energy production and using CO
2
as the sole carbon source. Cells are nonmotile, regular to irregular cocci, and possess several flagella. F
420
‐based autofluorescence is observed. Formate, acetate, methanol, trimethylamines, and alcohols are not utilized for methanogenesis. Grows autotrophically, yeast extract and acetate are not required for growth. Selenium and tungsten solution stimulate growth. NaCl required for growth. The habitat is hydrothermal vents. The genus consists of a single species
Methanofervidicoccus abyssi
.

DNA G + C content (mol%)
: 35.9 (HPLC), 35.3 (draft genome sequence).

Type species
:
Methanofervidicoccus abyssi
Sakai et al. 2019
VP
.
Halosegnis
Authors: Durán‐Viseras Ana , Sánchez‐Porro Cristina , Ventosa Antonio 
Published: December 2022

Abstract

Ha.lo.seg'nis. Gr. masc. n.
hals, halos
, salt; L. masc. adj.
segnis
, slow; N.L. masc. n.
Halosegnis
, a slow salt [growing] organism.

Euryarchaeota / Halobacteria / Halobacteriales / Haloarculaceae / Halosegnis

The genus
Halosegnis
is classified within the family
Haloarculaceae
, order
Halobacteriales
, and to the class
Halobacteria
. The cells are Gram‐stain‐negative, nonmotile rods, producing red‐ to light red‐pigmented colonies. Strictly aerobic. Extremely halophilic. Optimal growth at 20–25% (w/v) NaCl, at pH 7.5, and 37°C. Heterotrophic. Catalase‐positive but oxidase‐negative. The major polar lipids include biphosphatidylglycerol (BPG), phosphatidylglycerol (PG), phosphatidylglycerol phosphate methyl ester (PGP‐Me), phosphatidylglycerol sulfate (PGS), one glycolipid chromatographically identical to sulfated mannosyl glucosyl diether (S‐DGD‐1), sulfated triglycosyl diphytanyl archaeol ester linked to phosphatidic acid (S‐TGD‐1‐PA), and sulfated tetraglycosyl diether (S‐TeGD). Currently, the genus includes two species:
Halosegnis rubeus
(type species of the genus) and
Halosegnis longus
. Both species were isolated from marine salterns, but they are widely distributed in hypersaline aquatic habitats, especially at intermediate salinities.

DNA G + C content (mol%):
64.7–66.0 (genome).

Type species:
Halosegnis rubeus
Durán‐Viseras et al. 2021, VL203.
Salinadaptatus
Authors: Zhou Heng , Xue Qiong , Zhao Dahe , Xiang Hua 
Published: December 2022

Abstract

Sa.lin.a.dap.ta'tus. L. fem. pl. n.
salinae
, salterns, salt works; L. part. adj.
adaptatus
, adapted to a thing; N.L. masc. n.
Salinadaptatus
, an archaeon adapted to salt.

Euryarchaeota / Halobacteria / Natrialbales / Natrialbaceae / Salinadaptatus

Salinadaptatus
is a genus of haloalkaliphilic archaea. Cells are Gram‐stain‐negative, motile, strictly aerobic, and rod shaped.
Salinadaptatus
species are able to grow in the presence of 2.6–5.3 M NaCl (optimum 4.4 M), at 30–50°C (optimum 42°C), and pH 7.0–10.0 (optimum 8.0–8.5).
Salinadaptatus
species can utilize glycerol,
d
‐glucose,
d
‐galactose, sucrose, lactose,
d
‐sorbitol, acetate, succinate,
l
‐malate, fumarate,
l
‐glutamate, citrate, and
l
‐aspartate, but chitin, mannose, maltose, starch, pyruvate, lactate,
l
‐alanine,
l
‐ornithine,
d
‐fructose,
d
‐sorbose,
d
‐xylose, glycine,
l
‐arginine, and
l
‐lysine are not utilized. The polar lipids are phosphatidylglycerol and phosphatidylglycerol phosphate methyl ester. No glycolipids were detected. Phylogenetic trees based on 16S rRNA gene sequences and concatenated amino acid sequences of 122 single‐copy conserved proteins revealed a robust lineage of the genus with members of the related genera of the family
Natrialbaceae
. Known habitats are saline environments.

DNA G + C content (mol%)
:
62.06.

Type species:
Salinadaptatus halalkaliphilus

Xue et al. 2021
VP
.
Dethiobacterales ord. nov.
Authors: Sorokin Dimitry Y. , Merkel Alexander Y. 
Published: December 2022

Abstract

De.thi'o.bac.ter.a.les. N.L. masc. n.
Dethiobacter
, the type genus of the order; L. fem. pl. n. suff.
‐ales
, ending to denote an order; N.L. fem. pl. n.
Dethiobacterales
, the order of the genus
Dethiobacter
.

Firmicutes D / Dethiobacteria / Dethiobacterales ord. nov.

The order
Dethiobacterales
is the only order of the class
Dethiobacteria
, which forms a deep‐branching phylogenetic lineage within the phylum “
Firmicutes D
.” It consists of a single family
Dethiobacteraceae
and genus
Dethiobacter
, whose members are haloalkaliphilic anaerobes with a respiratory metabolism.
Kephallenia (Cephallenia)
Authors: Bonelou Elena 
Published: December 2022

AbstractKephallenia is situated at the western opening of the Corinthian Gulf. It was named after the mythical founder of the island, Kephalos. During the Late Bronze Age, Kephallenia turned into a significant Mycenaean center. In Classical times, Thucydides (2.30.2) referred to Kephallenia astetrapolisand named four cities: Pale, Krane, Same, and Pronnoi. During the Roman period a new city, Panormos, was established at the northern part of the island.
Enabling Efficient Blue‐Emissive Circularly Polarized Luminescence by In Situ Crafting of Chiral Quasi‐2D Perovskite Nanosheets within Polymer Nanofibers
Authors: Wen Zhangchuan , Lu Rong , Gu Fan , Zheng Kai , Zhang Lijie , Jin Huile , Chen Yihuang , Wang Shun , Pan Shuang 
Published: December 2022

AbstractChiral perovskite materials have intrigued enormous interests because of their appealing chiroptical properties and tailorable non‐centrosymmetric structures. However, it remains challenging to realize high‐efficiency blue emissive circularly polarized luminescence (CPL) of intrinsic chiral perovskite nanomaterials at room temperature. Herein, a robust and versatile electrospinning strategy is reported for in situ construction of chiral 2D and quasi‐2D perovskite nanosheets (PNSs) protected in polymer hybrid nanofibers. It is found that quasi‐2D chiral PNS/polymer possesses inherent chirality and enhanced CPL properties at room temperature compared to 2D counterparts. Notably, CPL emission color of chiral quasi‐2D PNS/polymer can be tuned from deep blue to sky blue, and a high luminescence dissymmetry values up to −8.0 × 10−3 can be achieved. Different perovskites, polymers, and nanofibrous structures are expanded to explore the universality of polymer protected PNSs. Significantly, compared to spin‐coated film, the stabilities of quasi‐2D PNS/polymer film are greatly improved due to the effective protection of polymer. The obtained PNS/polymer hybrid nanofiber films can be conveniently implemented for circularly polarized light emitting diode devices. This study may open up a new avenue for the scalable fabrication of chiral perovskite nanomaterials of interest and their applications in the CPL related fields.
Dichlorinated Organic‐Salt Terahertz Sources for THz Spectroscopy
Authors: Shin Bong‐Rim , Yu In Cheol , Jazbinsek Mojca , Yoon Woojin , Yun Hoseop , Kim Sang‐Wook , Kim Dongwook , Rotermund Fabian , Kwon O‐Pil 
Published: December 2022

AbstractAlthough in terahertz (THz) source materials molecular anions significantly influence the performance of THz generation, only limited classes of molecular counter anions have been reported. Here, utilizing dichlorinated molecular anions in THz generators is reported for the first time, to the best of our knowledge. In these new crystals, two dichlorinated molecular anions with different molecular symmetries, asymmetric 3,4‐dichlorobenzenesulfonate (34DCS) and symmetric 3,5‐dichlorobenzenesulfonate (35DCS), are incorporated with a 2‐(4‐hydroxystyryl)‐1‐methylquinolinium (OHQ) cation possessing top‐level molecular optical nonlinearity. OHQ‐34DCS exhibits a strong nonlinear optical response, in contrast to OHQ‐35DCS. In OHQ‐34DCS crystals, the dichlorinated groups form strong halogen bonds (XBs) and hydrogen bonds (HBs), which are beneficial for suppressing molecular (phonon) vibrations. The optical‐to‐THz conversion efficiency of the OHQ‐34DCS crystals is extremely high, comparable to that of the benchmark organic THz generators. Moreover, the THz emission spectra from the OHQ‐34DCS crystals, compared to those of previously reported benchmark analogous crystals, are stronger modulated toward a flatter shape, but possess substantially reduced spectral dimples. Therefore, the introduction of dichlorinated molecular anions is an efficient approach for the design of highly efficient electro‐optic salt crystals as efficient broadband THz wave sources.
Fast and Multifunctional Optically‐Driven Actuators based on Stable, Efficient, and Superhydrophobic Photothermal Paper Films
Authors: Wang Jiaying , Li Peihang , Jing Zhimin , Leydecker Tim , Neogi Arup , Wang Zhiming 
Published: December 2022

AbstractRemotely controlled self‐propelled optically‐driven actuators are increasingly attractive for sensing and robotic applications. However, complexities in material synthesis, multifunctionality, dynamic response, and the response rate limit their use for wide‐ranging application. This work uses a simple and efficient spraying method to prepare optically‐driven actuators based on TiN@PDMS‐PVDF (TiN@polydimethylsiloxane‐polyvinylidene difluoride) papers. The actuator exhibits stable superhydrophobicity for photothermal heating and corrosive solutions with a contact angle and sliding angle of 169.9° and 2.3°, respectively. The superhydrophobic actuators exhibit an efficient photothermal conversion aided by a very high optical absorption of the material approaching 97%. The optically‐driven actuator based on the TiN@PDMS‐PVDF paper exhibit a fast response and movement on the water surface. A 1.5 W cm−2 laser‐driven actuator yields a response time of 0.84 s, with its linear velocity approaching 10.1 mm s−1. The multifunctional optical‐driven actuators can easily perform operations such as linear and rotational motion optically engineered to avoid obstacles, transport cargo, and clean oil over a water surface. These fast, multifunctional, superhydrophobic actuators have bright prospects in many fields, such as bioengineering, environmental protection, and micro‐robots.
On‐Off Phagocytosis and Switchable Macrophage Activation Stimulated with NIR for Infected Percutaneous Tissue Repair of Polypyrrole‐Coated Sulfonated PEEK
Authors: Liu Xingdan , Zhang Haifeng , Yan Bangcheng , Yeung Kelvin W. K. , Liao Yun , Ouyang Liping , Liu Xuanyong 
Published: December 2022

AbstractIntelligent control of the immune response is essential for obtaining percutaneous implants with good sterilization and tissue repair abilities. In this study, polypyrrole (Ppy) nanoparticles enveloping a 3D frame of sulfonated polyether ether ketone (SP) surface are constructed, which enhance the surface modulus and hardness of the sulfonated layer by forming a cooperative structure of simulated reinforced concrete and exhibit a superior photothermal effect. Ppy‐coated SP could quickly accumulate heat on the surface by responding to 808 nm near‐infrared (NIR) light, thereby killing bacteria, and destroying biofilms. Under NIR stimulation, the phagocytosis and M1 activation of macrophages cultured on Ppy‐coated SP are enhanced by activating complement 3 and its receptor, CD11b. Phagocytosis and M1 activation are impaired along with abolishment of NIR stimulation in the Ppy‐coated SP group, which is favorable for tissue repair. Ppy‐coated SP promotes Collagen‐I, vascular endothelial growth factor, connective tissue growth factor, and α‐actin (Acta2) expression by inducing M2 polarization owing to its higher surface modulus. Overall, Ppy‐coated SP with enhanced mechanical properties could be a good candidate for clinical percutaneous implants through on‐off phagocytosis and switchable macrophage activation stimulated with NIR.