bluuebunny/crossref_metadata_2025_split huggingface dataset:
Manajemen Pemasaran Pendidikan di Sekolah Menengah Pertama (SMP) Islam Terpadu Izzuddin Palembang
Authors: Hidayat Hidayat 
Published: November 2022

Penelitian ini berjudul Manajemen Pemasaran Pendidikan di Sekolah Menengah Pertama (SMP) Islam Terpadu Izzuddin Palembang. Dasar pemikiran yang melatar belakangi penelitian ini adalah sekolah Islam terpadu Izzuddin merupakan salah satu lembaga pendidikan Islam yang banyak diminati oleh masyarakat, untuk masuk ke SMP Izzudin mengikuti tahapan secara ketat, baik mulai dari administrasi, seleksi dan tes semuanya diawasi secara ketat. Selain itu SMP Izzuddin tetap bertahan dan mengalami perkembangan yang sangat pesat setiap tahunnya, selalu menambahkan fasilitas belajar dan membangun gedung baru dikarenakan setiap tahunnya jumlah siswa baru selalu bertambah. Adapun rumusan masalah dalam penelitian ini yakni bagaimana manajemen pemasaran pendidikan dan apa saja faktor pendukung dan penghambat dalam Manajemen pemasaran pendidikan di SMP IT Izzuddin Palembang. Penelitian ini merupakan penelitian lapangan yang bersifat deskriptif kualitatif, informan pokok adalah bagian marketing SMP Izzuddin, dan informan pendukung adalah kepala sekolah, dan koordinator TU. Teknik pengumpulan data melalui wawancara, dokumentasi, observasi. Teknik analisis data yakni reduksi data, penyajian data, verifikasi, Kemudian menggunakan triangulasi Adapun hasil penelitian ini adalah Manajemen pemasaran pendidikan di SMP IT Izzuddin Palembang. Pemasaran pendidikan yang dilakukan di SMP IT Izzuddin sudah baik, mulai perencanaan, yang disesuaikan dengan visi, misi dan tujuan sekolah, penentuan calon siswa dengan sistem seleksi yang ketat. Pelaksanaan pemasaran juga dilaksanakan dengan baik, melalui produk yang ditawarkan oleh sekolah ke masyarakat, promosi dilakukan dengan cara online dan offline, tempat dilengkapi sarana prasarana pembelajaran yang memadai, harga sangat tinggi akan tetapi tidak mengesampingkan kualitas SMP Izzuddin, tenaga pendidik memiliki kompetensi sesuai dengan pendidikan yang dibutuhkan oleh sekolah. Evaluasi sebelum dan sesudah penerimaan siswa baru. Adapun Faktor pendukung dalam pemasaran pendidikan adalah tenaga pemasaran, tenaga pendidik dan kependidikan, sarana dan prasarana, lokasi yang dekat dan mudah dijangkau oleh calon pelanggan. Faktor penghambat bisa dari tenaga pendidik dan kependidikan, rendahnya komunikasi, bersaing dengan lembaga pendidikan lain.
The Correlation between Fatigue and Quality of Life on Knee Osteoarthritis Patient at RSD dr. Soebandi Jember
Authors: Hermansyah Yuli , Ridlo Marwah Pradani , Wisudanti Desie Dwi 
Published: November 2022

Osteoarthritis (OA) is a form of chronic arthritis that mainly attacks the knee joint. The prevalence of knee OA in Indonesia, especially in East Java, is around 27% which is relatively high. Therefore, this study aims to determine the correlation between fatigue and quality of life from knee OA patients at RSD dr. Soebandi Jember. The methodology uses in this study is the analytical observational method with a cross-sectional survey as the research design. For the data, this study uses primary and secondary data. The primary data was obtained through online interviews by phone using a questionnaire instrument, namely Fatigue Assessment Scale (FAS) and World Health Organization Quality of Life (WHOQOL) – BREF. Then, the secondary data was obtained from the medical records of knee OA patients who were undergoing treatment at the RSD dr. Soebandi Jember in the period January 2019 to December 2020. The results of this study showed that the p-value of fatigue with quality of life domain 1 (physical health) was 0.042, domain 2 (psychological) was 0.087, domain 3 (social) was 0.221, and domain 4 (environmental) was 0.426. Therefore, this study concludes that there is a weak relationship between fatigue and quality of life on domain 1 (physical health), with a correlation coefficient of 0.373. Also, there is no relationship between fatigue and quality of life on domain 2 (psychological), domain 3 (social), and domain 4 (environmental) in knee OA patients at RSD dr. Soebandi Jember.
Keywords: knee OA, fatigue, quality of life
Identification of Intestinal Protozoa in Adults in Pasie Nan Tigo Sub-Distric Koto Tangah Padang
Authors: Fitria Genia Alda , Irawati Nuzulia , Firdawati Firdawati 
Published: November 2022

Intestinal protozoan infection is one of the leading causes of morbidity and mortality worldwide. However, it is difficult to estimate the true problem of protozoal infections because cases are under-reported. This study aimed to identify intestinal protozoa in healthy adults. This study used a categorical descriptive research design and used a multistage random sampling technique. This research was conducted in Pasie Nan Tigo, Koto Tangah, Padang from July 2020 to December 2021 with a total of 61 samples obtained. Furthermore, the samples were examined using the direct stool examination method and with modified Ziehl-Neelsen staining. The results of this study were obtained, from 61 subjects the most age group was 45-49 years (27.9%), the most gender was female (88.5%), and the incidence of intestinal protozoal infection was 3.3% where only Blastocystis hominis found. The vacuole stage and cyst stage were found to be 50%, respectively. All samples examined were single infection. The conclusion of this study is that Blastocystis hominis infection is still found in healthy adults in Pasie Nan Tigo, Koto Tangah, Padang. Therefore, supportive therapy and measures to prevent infection transmission need to be carried out so that the incidence and morbidity rates can be reduced.
Keywords: Intestinal protozoa infections, healthy adult
The LC-MS/MS Profile and Total Phenolic Content of Telang Flower Extract and Roselle as NPC1L1 Inhibitor Candidate
Authors: Susanti Erna , Sari Meiria Istiana 
Published: November 2022

Inhibition of atherogenesis can be done through several mechanisms, one of which is inhibiting intestinal cholesterol absorption through inhibition of NPC1L1. The activity of Telang flower extract in overcoming various problems of degenerative diseases, especially cardiovascular disease, has been proven by many scientific studies. Likewise, related to the activity of Rosella flowers. Previous research conducted by researchers showed the potential of Rosella flower extract as an LXR agonist, one of the pathways that play a role in NPC1L1 inhibition. The combination of the two extracts is expected to increase its activity as a candidate for NPC1L1 inhibitor. The purpose of this study was based on the results of the determination of total phenolic levels and the characterization of the active compounds with LC MS/MS extracts of telang flower and rosella, which are expected to be developed into further research in vivo to strengthen scientific evidence so that they can be developed into phytopharmaca preparations. Instrumentation analysis method with LC-MS/MS to identify the content of active compounds and determination of total phenolic content with Folin ciocalteu in order to obtain standardized extracts of telang flower and roselle. The results of this study showed that the total phenolic content based on the largest order was purple rosella flower extract (114.129.35 ± 266.20 g GAE), a combination of purple rosella and telang flower extract (101.760.58 ± 116.09 g GAE), telang flower extract (90.477.41 ± 107.38 g GAE) and extract red rosella flowers (84,601.00 ± 266.91 g GAE). The combination of extracts showed reduced total phenolic content compared to the single extract. The phenolic content in each extract affected the total phenolic in the combination of extracts. 8 anthocinin compounds were identified in both the telang flower extract and the rosella flower extract.
Keywords: NPC1L1 inhibitor, telang, extract, Roselle, total phenolics, LC-MS/MS, atherogenesis
Low Oxygen Tension Inhibits Senescence in Bone Marrow Mesenchymal Stem Cells (BMSCs)
Authors: Bumi Candra 
Published: November 2022

Background: Stem cells have been used in regenerative medicine but are so few in the body that they require cell culture. Stem cell culture was performed under normal oxygen tension and passage was carried out until the number of cells was sufficient for therapy. Stem cell cultures under normal oxygen tension do not match the stem cell microenvironment, which can lead to premature senescence. This study aims to determine the association of low oxygen tension with premature senescence of mesenchymal stem cells (MSCs) through inhibition of p21 expression by HIF-1a. Methode: The research method used rabbit bone marrow in New Zealand as a source of MSCs. The results of isolation of MSCs were divided into two groups for cultured on normal and low oxygen tension until 10 passages. Cells were identified using flowcytometry for cd105 and cd34. At early and late passage, the expression of p21 and HIF-1a was examined using immunofluorescence while senescence was examined using β-galactosidase assay. Results: The results showed that in low oxygen cultures HIF-1a expression increased significantly (p <0.05) while p21 expression decreased significantly (p <0.05) as did the β-galactosidase assay. Conclusions: The conclusion of this research is low oxygen tension culture able to decrease premature senescence culture of invitro stem cells mesenchymal through obstacles p21 by HIF-1a.
Keywords: p21 expression, HIF-1a expression, late passage, premature senescence.
MONITORING OF MICROBIOLOGY QUALITY RAW WATER AND REFILLED DRINKING WATER DURING COVID-19
Authors: Herniwanti Herniwanti , Rahayu Endang Purnawati 
Published: November 2022

Introduction: Riau province regency / city data for drinking water depots in 2020 show that the largest number of Pekanbaru City in Riau Province has refill drinking water depots, there are 440 depots consisting of 220 feasible depots while 227 depots are not feasible. This research was conducted in the Tampan sub-district which is the most densely populated city of Pekanbaru. The purpose of this study was to evaluate the microbiological quality standards (Coliform) for refill drinking water depot, raw water source quality standards and population well quality standards during Covid-19. Methods: This research is quantitative descriptive analytic with triangulation methods observation with laboratory tests, in-depth interviews with correspondents of depot officers and residents of drinking water wells. The test was carried out at the UPT health and environment laboratory of the Riau provincial health office. Result: Data analysis compared 7 samples with laboratory test results according to quality standards. The results of the analysis stated that there were no Coliform bacteria in the tested samples. The source of raw water from housing will have better standard of quality the deeper it is. Conclusion: There is no periodic supervision from the health office / Puskesmas to drinking water depot during the Covid-19 period which is usually routinely carried out every 3-6 months according to regulation of ministers of health no.736,2010 concerning supervision of drinking water quality. Housing developers are required to provide a clean water source from a proper borehole from the start of housing development.
KNN imputation to missing values of regression-based rain duration prediction on BMKG data
Authors: Oktaviani Ikke Dian , Putrada Aji Gautama 
Published: November 2022

The prediction of rain duration based on data from the Meteorology, Climatology, and Geophysics Agency (BMKG) is an important issue but remains an open problem. At the same time, several studies have shown that missing values can cause a decrease in the performance of the model in making predictions. This study proposes k-nearest neighbors (KNN) imputation to overcome the problem of missing values in predicting rain duration. The source of the rain duration prediction dataset is the BMKG data. We compared gradient boosting regression (GBR), adaptive boosting regression (ABR), and linear regression (LR) for the regression model for predicting rain duration. We compared the KNN imputation method with several benchmark methods, including zero imputation, mean imputation, and iterative imputation. Parameters r2, mean squared error (MSE) and mean bias error (MBE) measure the performance of these imputation methods. The test results show that for rain duration prediction using the regression method, GBR shows the best performance, both for train data and test data with r2 = 0.915 and 0.776, respectively. Then our proposed KNN imputation has the best performance for missing value imputation compared to the benchmark imputation method. The prediction values of r2 and MSE when using KNN imputation at Missing Percentage = 90% are 0.71 and 0.36, respectively.
Technology Development Framework: Moving from Qualitative toward Quantitative Decision-Making
Authors: Clark Hamish P. , Castellanos Diaz Orlando 
Published: November 2022

SummaryTechnology development in the energy sector typically suffers from an ad hoc approach to making decisions about the key questions of “What is the next derisking step?” and “At what scale?” This lack of structure in decision-making occurs despite the technology development process usually being within a stage-gated protocol. This often leads to significant waste of time and resources and plenty of “surprises” about the extent of additional testing required.The approach proposed in this paper is relatively simple to use, scalable, and transferable across industry sectors. Consistent application of the methodology has the potential to bring a quantitative rigor that can lead to more effective and efficient technology development and improve both intellectual and monetary capital allocation. Additionally, the framework provided facilitates a more structured and faster learning curve for people moving into technology development roles. Starting with a high-level understanding of the technology and business case, the methodology identifies possible commercial deployments and associates key technical and commercial risks that can be barriers to commercialization. Then, using a “risk burndown” approach based around an initial assessment of probability of success (POS), different paths to deployment (PTDs) are developed. A value of information (VOI) approach is used to evaluate key metrics. This leads to a diverse set of derisking options with associated trade-offs for informed decision-making.The methodology has been developed and deployed since 2017 across a portfolio of both incremental improvement and game-changing subsurface technologies at Suncor Energy, a large integrated Canadian energy company. More than 25 technologies have been progressed using elements of this workflow with 7 of the more complex and expensive projects using the full quantitative VOI approach. These analyses have been used to inform decision-making on more than $400 million1 of proposed derisking activity spend.
Correlation between Default mode network and Symptomatic Domains: A Spectral Approach to Schizophrenia
Authors: Sánchez Ana María Granados , Zapata Juan Felipe Orejuela , Dávila César Augusto Arango , Arango Isabella Moreno 
Published: November 2022

Abstract
Introduction
When evaluating psychiatric pathologies using imaging studies, the categorical approach supposes a significant challenge. Redefining these pathologies with the use of behavioral dimensions that are related to brain biology has been attempted. This paper aims to describe the findings on functional magnetic resonance imaging in patients with schizophrenia and correlate it with their symptomatic domains.
Materials and methods
This study is a descriptive, observational, transversal study. Fourteen patients with schizophrenia and Fourteen controls were explored using functional magnetic resonance during a resting period and developing easy, medium, and complex tasks. The default mode network was evaluated, registering the voxel activation on a cluster and its maximum activation over interest areas. Subjects were interrogated using the Derogatis Symptom Checklist (SCL-90-R) and correlation coefficients were applied for data analysis.
Results
Diminished activation of the default mode network was evidenced in association with the complexity of the task in the control group. Patients presented a steady activation when comparing their resting state with the activation during the different tasks. A negative correlation was observed implicating the volume of the functional cluster in the posterior cingulate cortex during the high complexity task and the interpersonal sensitivity domain. A moderate positive correlation was found with symptomatic domains of interpersonal sensitivity, hostility, phobia, and depression, while a moderate negative association was found with psychosis.
Conclusions
Imaging evaluation of the psychiatric pathologies could be useful if the pathology is approached through the spectrum of symptomatic domains. This perspective would enhance the assertiveness of the therapeutics.
Trends in Emergency Department Anticoagulant Prescription for Patients with Venous Thromboembolism in China, 2016-2019
Authors: Wang Xia , Liu Xin , Zhao Zhigang , Guo Wei 
Published: November 2022

Abstract
Introduction:
Untreated acute venous thromboembolism (VTE) can have catastrophic consequences. Patients should be anticoagulated as soon as VTE is diagnosed. Based on the current clinical guidelines, direct oral anticoagulants (DOACs) are recommended as the first-line anticoagulant treatment for VTE. However, the selection of anticoagulants is a complex task, especially in the emergency department (ED).
Methods
This population-based drug utilization study was conducted to investigate the status of anticoagulant prescriptions for VTE treated in the ED (ED-VTE; ICD-10 codes I26, I80, I82, and I27.82) and the trend in these prescriptions in four major Chinese cities (Beijing, Tianjin, Shanghai, and Guangzhou) between 2016.1.1 and 2019.12.31. All data were retrieved from a cooperative data program established by the Peking Union Medical College Hospital. Patients who were anticoagulated for initial or recurrent VTE in the EDs of participating institutions during the study period were included in the present analysis. The primary objective was to characterize the trend in anticoagulant prescriptions for ED-VTE; the secondary objective was to calculate the average cost of anticoagulants per prescription. The sample size was not estimated before data collection due to the retrospective nature of the study and the current scarcity of data on anticoagulant prescribing for ED-VTE.
Results
a total of 4609 prescriptions for anticoagulants were retrieved; none of these records was found to have incomplete data. The anticoagulants prescribed in the current study included low-molecular-weight heparin (LMWH), warfarin, dabigatran, and rivaroxaban. Of the included prescriptions, 63.9% were given to patients over 65 years old, and 55.0% were given to females. The city of Shanghai accounted for nearly half of the prescriptions. Generally, LMWH was the most frequently prescribed anticoagulant in the ED. Warfarin accounted for more than 60% of all oral anticoagulant prescriptions during the study period; the second most prescribed oral anticoagulant was rivaroxaban (32.1%). The utilization of rivaroxaban increased to 48.4% of all oral anticoagulants in 2019. Dabigatran was less frequently prescribed.
Conclusion
The selection of anticoagulants in the ED was complex. LMWH remained the most prescribed anticoagulant regardless of time, gender, institution location, or cost. Warfarin was the most prescribed oral anticoagulant from 2016 to 2018, but the number of rivaroxaban prescriptions exceeded the number of warfarin prescriptions in 2019. DOACs accounted for an increasing share of anticoagulant prescriptions during the study period. Further investigations are warranted.
Uncertain Portfolio Optimization based on Tsallis Entropy of Uncertain Sets
Authors: Xie Faqi , Zhao Hua , Ahmadzade Hamed , GaesmiGol Mohammad 
Published: November 2022

Abstract
Tsallis entropy is a flexible device to measure indeterminacy of uncertain sets. A formula is obtained to calculate Tsallis entropy of uncertain sets via inversion of membership functions. Also, by considering Tsallis entropy as a risk measure, we optimize portfolio selection problems via mean-entropy models.
LAB: A Leader-Advocate-Believer Based Optimization Algorithm
Authors: Reddy Ruturaj , Kulkarni Anand J , Krishnasamy Ganesh , Shastri Apoorva Sanket , Gandomi Amir H 
Published: November 2022

Abstract
This manuscript introduces a new socio-inspired metaheuristic technique referred to as Leader-Advocate-Believer based optimization algorithm (LAB) for engineering and global optimization problems. The proposed algorithm is inspired by the AI-based competitive behaviour exhibited by the individuals in a group while simultaneously improving themselves and establishing a role (Leader, Advocate, Believer). LAB performance in computational time and function evaluations are benchmarked using other metaheuristic algorithms. The LAB algorithm was applied for solving engineering problems, including abrasive water jet machining, electric discharge machining, micromachining processes and turning of titanium alloy in a minimum quantity lubrication environment. The results were compared with other algorithms such as Firefly Algorithm, Cohort Intelligence, Genetic Algorithm, Simulated Annealing, Particle Swarm Optimisation and Multi-Cohort Intelligence. The results from this study highlighted that the LAB outperforms the other algorithms in terms of function evaluations and computational time. The prominent features and limitations of the LAB algorithm are also discussed.
Lateral Torsional Buckling Effect on I- Section With Flange Bracing as Per IS 800:2007
Authors: Pandit Poornachandra , Venkata Praneeth D , Rahmatulla Mohammad 
Published: November 2022

Abstract
The lateral-torsional buckling occurs in a beam when the beam's unsupported length is greater. The beam will fail by lateral-torsional buckling when the compression flange is free to rotate and displace laterally. The lateral stability of the I-section is an important factor in the design of pre-engineered buildings. The design to resist the bending and twisting in the frame I-section that is rafter and column in lateral direction flange bracing acts as a restraint to resist lateral-torsional buckling. The top flange is connected with purlins to act as a lateral restraint. The bottom flange torsional moment is resisted by flange bracing. Increasing the flange bracing decreases the unsupported length of the compression flange, so there is a decrease in lateral-torsional buckling. If the non-dimensional slenderness ratio ( λlt < 0.4 ) the section is said to be laterally supported, according to IS 800. In this paper, how the lateral-torsional buckling affects when the restraints are provided at different intervals and how the section will be affected when the flange width, thickness, web depth and thickness changes.