bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ten new insights in climate science 2022
Authors: Martin Maria A. , Boakye Emmanuel A. , Boyd Emily , Broadgate Wendy , Bustamante Mercedes , Canadell Josep G. , Carr Edward R. , Chu Eric K. , Cleugh Helen , Csevár Szilvia , Daoudy Marwa , de Bremond Ariane , Dhimal Meghnath , Ebi Kristie L. , Edwards Clea , Fuss Sabine , Girardin Martin P. , Glavovic Bruce , Hebden Sophie , Hirota Marina , Hsu Huang-Hsiung , Huq Saleemul , Ingold Karin , Johannessen Ola M. , Kameyama Yasuko , Kumarasinghe Nilushi , Langendijk Gaby S. , Lissner Tabea , Lwasa Shuaib , Machalaba Catherine , Maltais Aaron , Mathai Manu V. , Mbow Cheikh , McNamara Karen E. , Mukherji Aditi , Murray Virginia , Mysiak Jaroslav , Okereke Chukwumerije , Ospina Daniel , Otto Friederike , Prakash Anjal , Pulhin Juan M. , Raju Emmanuel , Redman Aaron , Rigaud Kanta K. , Rockström Johan , Roy Joyashree , Schipper E. Lisa F. , Schlosser Peter , Schulz Karsten A. , Schumacher Kim , Schwarz Luana , Scown Murray , Šedová Barbora , Siddiqui Tasneem A. , Singh Chandni , Sioen Giles B. , Stammer Detlef , Steinert Norman J. , Suk Sunhee , Sutton Rowan , Thalheimer Lisa , van Aalst Maarten , van der Geest Kees , Zhao Zhirong Jerry 
Published: December 2022

Non-technical summaryWe summarize what we assess as the past year's most important findings within climate change research: limits to adaptation, vulnerability hotspots, new threats coming from the climate–health nexus, climate (im)mobility and security, sustainable practices for land use and finance, losses and damages, inclusive societal climate decisions and ways to overcome structural barriers to accelerate mitigation and limit global warming to below 2°C.Technical summaryWe synthesize 10 topics within climate research where there have been significant advances or emerging scientific consensus since January 2021. The selection of these insights was based on input from an international open call with broad disciplinary scope. Findings concern: (1) new aspects of soft and hard limits to adaptation; (2) the emergence of regional vulnerability hotspots from climate impacts and human vulnerability; (3) new threats on the climate–health horizon – some involving plants and animals; (4) climate (im)mobility and the need for anticipatory action; (5) security and climate; (6) sustainable land management as a prerequisite to land-based solutions; (7) sustainable finance practices in the private sector and the need for political guidance; (8) the urgent planetary imperative for addressing losses and damages; (9) inclusive societal choices for climate-resilient development and (10) how to overcome barriers to accelerate mitigation and limit global warming to below 2°C.Social media summaryScience has evidence on barriers to mitigation and how to overcome them to avoid limits to adaptation across multiple fields.
In Situ Ion Composition Observations of Ganymede's Outflowing Ionosphere
Authors: Valek P. W. , Waite J. H. , Allegrini F. , Ebert R. W. , Bagenal F. , Bolton S. J. , Connerney J. E. P. , Kurth W. S. , Szalay J. R. , Wilson R. J. 
Published: December 2022

AbstractOn 7 June 2021 the Juno spacecraft passed through the Ganymede magnetosphere, with a closest approach altitude of 1,046 km. The Jovian Auroral Distributions Experiment‐Ion (JADE‐I) sensor observed ionospheric ions, consisting of O2+, O+, H2+, H+, and H3+. These ions were outflowing, with no bi‐directional flow except possibly near the magnetopause. Relative ion densities with respect to time agree the electron density determined by the Waves instrument, but are ∼2.5 times larger. The light ions appear to be in hydrostatic equilibrium because the altitude profile is generally symmetric between inbound and outbound legs of the flyby. H3+ ions are an exception to this, with the ratio of H3+/H2+ being ∼a factor 4 lower on the outbound than the inbound leg. The heavy ions have higher densities outbound than inbound. The outflowing flux of light ions peak near closest approach, but the heavy ions peak outbound of the flyby.
Circulating adipokine levels and COVID-19 severity in hospitalized patients
Authors: Flikweert Antine W. , Kobold Anneke C. Muller , van der Sar-van der Brugge Simone , Heeringa Peter , Rodenhuis-Zybert Izabela A. , Bijzet Johan , Tami Adriana , van der Gun Bernardina T. F. , Wold Karin I. , Huckriede Anke , Franke Hildegard , Emmen Judith M. A. , Emous Marloes , Grootenboers Marco J. J. H. , van Meurs Matijs , van der Voort Peter H. J. , Moser Jill 
Published: December 2022

Abstract
Background
Obesity is a risk factor for adverse outcomes in COVID-19, potentially driven by chronic inflammatory state due to dysregulated secretion of adipokines and cytokines. We investigated the association between plasma adipokines and COVID-19 severity, systemic inflammation, clinical parameters, and outcome of COVID-19 patients.

Methods
In this multi-centre prospective cross-sectional study, we collected blood samples and clinical data from COVID-19 patients. The severity of COVID-19 was classified as mild (no hospital admission), severe (ward admission), and critical (ICU admission). ICU non-COVID-19 patients were also included and plasma from healthy age, sex, and BMI-matched individuals obtained from Lifelines. Multi-analyte profiling of plasma adipokines (Leptin, Adiponectin, Resistin, Visfatin) and inflammatory markers (IL-6, TNFα, IL-10) were determined using Luminex multiplex assays.

Results
Between March and December 2020, 260 SARS-CoV-2 infected individuals (age: 65 [56–74] BMI 27.0 [24.4–30.6]) were included: 30 mild, 159 severe, and 71 critical patients. Circulating leptin levels were reduced in critically ill patients with a high BMI yet this decrease was absent in patients that were administered dexamethasone. Visfatin levels were higher in critical COVID-19 patients compared to non-COVID-ICU, mild and severe patients (4.7 vs 3.4, 3.0, and 3.72 ng/mL respectively, p < 0.05). Lower Adiponectin levels, but higher Resistin levels were found in severe and critical patients, compared to those that did not require hospitalization (3.65, 2.7 vs 7.9 µg/mL, p < 0.001, and 18.2, 22.0 vs 11.0 ng/mL p < 0.001).

Conclusion
Circulating adipokine levels are associated with COVID-19 hospitalization, i.e., the need for oxygen support (general ward), or the need for mechanical ventilation and other organ support in the ICU, but not mortality.
Antarctic fungi with antibiotic potential isolated from Fort William Point, Antarctica
Authors: Ordóñez-Enireb Eunice , Cucalón Roberto V. , Cárdenas Diana , Ordóñez Nadia , Coello Santiago , Elizalde Paola , Cárdenas Washington B. 
Published: December 2022

AbstractThe Antarctic continent is one of the most inhospitable places on earth, where living creatures, mostly represented by microorganisms, have specific physiological characteristics that allow them to adapt to the extreme environmental conditions. These physiological adaptations can result in the production of unique secondary metabolites with potential biotechnological applications. The current study presents a genetic and antibacterial characterization of four Antarctic fungi isolated from soil samples collected in Pedro Vicente Maldonado Scientific Station, at Fort William Point, Greenwich Island, Antarctica. Based on the sequences of the internal transcribed spacer (ITS) region, the fungi were identified as Antarctomyces sp., Thelebolus sp., Penicillium sp., and Cryptococcus gilvescens. The antibacterial activity was assessed against four clinical bacterial strains: Escherichia coli, Klebsiella pneumoniae, Enterococcus faecalis, and Staphylococcus aureus, by a modified bacterial growth inhibition assay on agar plates. Results showed that C. gilvescens and Penicillium sp. have potential antibiotic activity against all bacterial strains. Interestingly, Thelebolus sp. showed potential antibiotic activity only against E. coli. In contrast, Antarctomyces sp. did not show antibiotic activity against any of the bacteria tested under our experimental conditions. This study highlights the importance of conservation of Antarctica as a source of metabolites with important biomedical applications.
Engineering Pseudomonas putida KT2440 for chain length tailored free fatty acid and oleochemical production
Authors: Valencia Luis E. , Incha Matthew R. , Schmidt Matthias , Pearson Allison N. , Thompson Mitchell G. , Roberts Jacob B. , Mehling Marina , Yin Kevin , Sun Ning , Oka Asun , Shih Patrick M. , Blank Lars M. , Gladden John , Keasling Jay D. 
Published: December 2022

AbstractDespite advances in understanding the metabolism of Pseudomonas putida KT2440, a promising bacterial host for producing valuable chemicals from plant-derived feedstocks, a strain capable of producing free fatty acid-derived chemicals has not been developed. Guided by functional genomics, we engineered P. putida to produce medium- and long-chain free fatty acids (FFAs) to titers of up to 670 mg/L. Additionally, by taking advantage of the varying substrate preferences of paralogous native fatty acyl-CoA ligases, we employed a strategy to control FFA chain length that resulted in a P. putida strain specialized in producing medium-chain FFAs. Finally, we demonstrate the production of oleochemicals in these strains by synthesizing medium-chain fatty acid methyl esters, compounds useful as biodiesel blending agents, in various media including sorghum hydrolysate at titers greater than 300 mg/L. This work paves the road to produce high-value oleochemicals and biofuels from cheap feedstocks, such as plant biomass, using this host.
Stabilization mechanism of molecular orbital crystals in IrTe2
Authors: Ritschel Tobias , Stahl Quirin , Kusch Maximilian , Trinckauf Jan , Garbarino Gaston , Svitlyk Volodymyr , Mezouar Mohamed , Yang Junjie , Cheong Sang-Wook , Geck Jochen 
Published: December 2022

AbstractDoped IrTe2 is considered a platform for topological superconductivity and therefore receives currently a lot of interest. In addition, the superconductivity in these materials exists in close vicinity to electronic order and the formation of molecular orbital crystals, which we explore here by means of high-pressure single crystal x-ray diffraction in combination with density functional theory. Our crystallographic refinements provide detailed information about the structural evolution as a function of applied pressure up to 42 GPa. Using this structural information for density functional theory calculations, we show that the local multicenter bonding in IrTe2 is driven by changes in the Ir-Te-Ir bond angle. When the electronic order sets in, this bond angle decreases drastically, leading to a stabilization of a multicenter molecular orbital bond. This unusual local mechanism of bond formation in an itinerant material provides a natural explanation for the different electronic orders in IrTe2. It further illustrates the strong coupling of the electrons with the lattice and is most likely relevant for the superconductivity in this material.
The importance of localized modes spectral contribution to thermal conductivity in amorphous polymers
Authors: Li Buxuan , DeAngelis Freddy , Chen Gang , Henry Asegun 
Published: December 2022

AbstractPolymers are a unique class of materials from the perspective of normal mode analysis. Polymers consist of individual chains with repeating units and strong intra-chain covalent bonds, and amorphous arrangements among chains with weak inter-chain van der Waals and for some polymers also electrostatic interactions. Intuitively, this strong heterogeneity in bond strength can give rise to special features in the constituent phonons, but such effects have not been studied deeply before. Here, we use lattice dynamics and molecular dynamics to perform modal analysis of the thermal conductivity in amorphous polymers. We find an abnormally large population of localized modes in amorphous polymers, which is fundamentally different from amorphous inorganic materials. Contrary to the common picture of thermal transport, localized modes in amorphous polymers are found to be the dominant contributors to thermal conductivity. We find that a significant portion of the localization happens within individual chains, but heat is dominantly conducted when localized modes involve two chains. These results suggest localized modes generally play a key role in thermal transport for different polymers. The results provide an alternative perspective on why polymer thermal conductivity is generally quite low and gives insight into how to potentially change it.
The increasing role of structural proteomics in cyanobacteria
Authors: Sound Jaspreet K. , Bellamy-Carter Jeddidiah , Leney Aneika C. 
Published: December 2022

Abstract
Cyanobacteria, also known as blue–green algae, are ubiquitous organisms on the planet. They contain tremendous protein machineries that are of interest to the biotechnology industry and beyond. Recently, the number of annotated cyanobacterial genomes has expanded, enabling structural studies on known gene-coded proteins to accelerate. This review focuses on the advances in mass spectrometry (MS) that have enabled structural proteomics studies to be performed on the proteins and protein complexes within cyanobacteria. The review also showcases examples whereby MS has revealed critical mechanistic information behind how these remarkable machines within cyanobacteria function.
Optimal transformer design of DAB converters in solid‐state transformers for maximum power efficiency
Authors: Lee Eun S. , Song Seung H. , Park Jin H. , Kim Myung R. 
Published: December 2022

AbstractSolid‐state transformers (SST) are a viable solution to replace the conventional low‐frequency transformer in railway vehicles. In the SST, high frequency transformers in dual‐active‐bridge (DAB) converters are essentially used for electrical insulation. Thus, the high‐frequency transformer design becomes so important to increase the high efficiency operation with electrical insulation. Here, an optimal transformer design methodology, which provides a maximum power efficiency operation of the transformer for DAB converters, is proposed. Considering the core loss and copper loss of the transformer, the optimal number of turns for the transformer in a DAB converter N1,op and N2,op can be determined so that the maximum power efficiency for the transformer is achieved at a normal operating point of the DAB converter. To derive the major loss parameters, a finite‐element‐method based simulation was performed for resistive and magnetic loss analysis, which eventually provided the optimal number of turns under the given physical size of ferrite core. The 20 W prototype for a DAB converter with EER2828 and EER3019 of ferrite core shapes were fabricated and verified by simulations and experiments. The results showed that the optimum number of turns N1,op were selected as 12 and 8 turns for two ferrite core models, respectively, which are most highest efficiencies with regard to the different winding turns. To apply the proposed methodology to the SST power level in railway vehicles, 125 kW transformers with inductor set for the SST applications has been fabricated and experimentally verified. As a result, 99.6% of highest efficiency with thermal stable operation was obtained by the proposed transformer design methodology.
Organersatzverfahren: Update Lungenersatzverfahren
Authors: Reyher Christian , Muellenbach Ralf Michael , Lepper Philipp Moritz , Mutlak Haitham 
Published: December 2022

ZusammenfassungDas akute Lungenversagen des Erwachsenen (ARDS) ist nach wie vor mit einer hohen Mortalität von ca. 40% belastet – eine große Herausforderung für die Intensivmedizin. Dieser Beitrag
erläutert, bei welchen Befundkonstellationen die Lungenersatzverfahren ECMO (extrakorporale Membranoxygenierung) und ECCO2R (extrakorporale CO2-Elimination) als
Rescue-Therapie zum Einsatz kommen können und worauf dabei zu achten ist.
Fe1+yTexSe1-x: a delicate and tunable Majorana material
Authors: Yang Fazhi , Phan Giao Ngoc , Zhang Renjie , Zhao Jin , Li Jiajun , Lu Zouyouwei , Schneeloch John , Zhong Ruidan , Ma Mingwei , Gu Genda , Dong Xiaoli , Qian Tian , Ding Hong 
Published: December 2022

Abstract
We report the observation for the pz electron band and the band inversion in Fe1+yTexSe1-x with angle-resolved photoemission spectroscopy. Furthermore, we found that excess Fe (y>0) inhibits the topological band inversion in Fe1+yTexSe1-x, which explains the absence of Majorana zero modes in previous reports for Fe1+yTexSe1-x with excess Fe. Basing on our analysis of different amounts of Te doping and excess Fe, we propose a delicate topological phase in this material. Thanks to this delicate phase, one may able to tune the topological transition via applying lattice strain or carrier doping.
Risk Management in the Development of a Regional Drinking Water Supply System
Authors: Kamaludin Tutang Muhtar , Rusdin Andi , Nirmalawati  , Fadjar Adnan , Wahab A 
Published: December 2022

Abstract
Clean water services are a vital need that must be provided to support the dynamics of regional growth. Infrastructure development, such as the provision of drinking water, is considered as one of the policy instruments for economic development, marked by the development of industries, settlements, regional expansion and the increasing need for drinking water. The checklist technique was used by researchers to obtain information from respondents about the application or implementation of risk management. The objective of this research is to identify risk management in the development of the Pasigala Regional Drinking Water Supply System (SPAM), Central Sulawesi Province. This type of research is a case study. This checklist consists of three parts, each of which is used to obtain data on risk identification, risk analysis, and risk treatment. From the analysis, 6 risks fall into the high category, these risks are that the quality of drinking water is not as expected, the Water Treatment Plant (WTP) has never functioned according to the planned capacity, the raw water transmission pipe is not in accordance with the minimum standard / technical specifications, the design raw water production units that have not been able to overcome turbidity due to sedimentation, natural disasters in the location area, and damage to the ecosystem around water sources.
Experimental study of harvest solar energy based on thermoelectric generator with configuration variations
Authors: Rahman YA , Amin N , Pirade Y S , Ainun A D 
Published: December 2022

Abstract
The background of this research is to optimize the use of heat from solar energy as energy harvesting based on a thermoelectric generator (TEG). One of the factors that affect the TEG output is the TEG configuration and the resulting temperature difference. The external temperature captured by the TEG side and the cooling system causes a significant temperature difference. This study uses a TEG trainer module consisting of eight TEGs and a double heatsink that functions for the cooling side and heat capture from the sun. Experiments show that the combination of eight TEG modules in series provides a maximum output significantly compared to single TEG and parallel modules at the same time with a temperature difference of 12.870C.
Examining the Intersection Performance of the Post-Disaster Permanent Housing Assistance Impact: A Study of the Trip Generation/Attraction in Palu City
Authors: Bahar T , Tahir A , Mashuri  , Isratun  
Published: December 2022

Abstract
The government provides housing assistance for victims of the disaster that hit Palu City in Central Sulawesi Province. Most of the housing assistance is in Tondo Village, which is referred to as Tondo’s permanent housing (Huntap Tondo). Currently, the TPH has become a source of traffic movement, especially for the Tondo ring road intersection - Street Untad 1. Thus, this study aims to examine the impact of the Tondo permanent residential trip generation/attraction on performing the intersection. The method of this research is to calculate the trip generation/attraction that occurs because of the existence of the Tondo’s permanent housing and calculate the performance of the Tondo ring road intersection - Street Untad 1 using the Indonesian Highway Capacity Manual (MKJI) in 1997. This study reveals the value of the trip generation/attraction rate that occurs in the the Tondo’s permanent housing is 0.175 pcu/unit with a total trip generation/attraction of 549 pcu/hr. Meanwhile, performing the ring road intersection Tondo - street Untad 1 decreased the value of saturation by 0.45 to 0.64, and the delay value of 8.63 seconds/pcu to 10.52 seconds/pcu.
Implementation of the souraja house façade on the composition of the government building façade in Palu city
Authors: Malik S M , Salenda H , Winarta A , Muhamad D R 
Published: December 2022

Abstract
As the capital city of Central Sulawesi Province, Palu has built various public buildings, especially buildings belonging to the local government, which are provided to serve the population’s needs. However, when examined more deeply, it can be seen that several government-owned public buildings were designed not to pay attention to the environmental conditions in which the building was erected both socially, culturally and the composition of the building’s constituents. One of them is the facade or the front of the building. The Souraja house, a traditional house of the Kaili tribe, which currently exists in Palu City, should become a reference for the shape of public buildings, both in overall form and only in the form of the facade composition. This study uses a rationalistic approach, which sees the truth from empirical conditions and arguments as a part of thinking construction. The rationalistic research design departs from the theoretical framework (Grand Theory). The source of the Grand theory raised in this study comes from the Souraja House building, which is the work of the traditional house of the Kaili tribe, which currently still exists in Palu City. The results of this study indicate that the three parameters of the components that make up the facade of the Souraja Traditional house, which are used in analyzing and discussing the beginning of government buildings in Palu City, are not 100% implemented, namely on the raised floor but no longer in the form of a stilt building. While the two parameters of the composition of the facade of the Souraja Traditional house used in analyzing and discussing the face of government buildings in Palu City are 100% implemented.
Kinship in the Establishment of Settlements for Remote Indigenous Peoples in Central Sulawesi
Authors: Mulyati A , Zaenal Z 
Published: December 2022

Abstract
The existence and implementation of living space pattern characterize settlements and is a specific model of living space. The management of living spaces is essential to the existence of culture and local wisdom. The study uses a naturalistic qualitative approach to find the concept of establishing settlements for disadvantaged indigenous communities. Residential homes form a linear line along the neighborhood road. Residential houses still use simple building materials, namely boards and bricks, like walls and zinc as roofs. Kinship is reflected, among others, in the relationship between residences in the form of open spaces, unlimited courtyards, functioning as play areas, or other interactive activities. This space equips with bale-bale or trees as protection. Other remaining slots use to raise livestock, toilets, laundry rooms, and food stalls. The displacement of settlements from the top of the mountains caused the fields as the primary source of livelihood to remain in their original places, equipped with their garden houses. The new residential environment has several facilities such as village offices, mosques, schools, and general facilities building. Deliberation, consensus, kinship, and cooperation remain the principles of settler life, reflected in the formation of unlimited space and carrying out various daily life activities.