bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structure of early signs of affective pathology in adolescents
Authors: Osipova N. , Bardenshteyn L. , Beglyankin N. , Aleshkina G. , Dmitriev M. 
Published: February 2022

IntroductionStudies in adults with bipolar disorder (BD), shows that in 25% of cases first affective episode occurs under the age of 13 and in 63-69% under the age of 19. The most difficult problem is the early identification of BD, which starts in adolescence as a result of polymorphism of clinical symptoms, their syndromic incompleteness.ObjectivesStudy of the structure of adolescents affective disorders on primary appointment in outpatient psychiatric unit.MethodsContent analysis, sampling method, statistical method. 120 disease histories of adolescents who first applied for outpatient psychiatric unit in 2019 were used. 93 (77.5%) of them were girls and 27 (22.5%) of them were boys. The average age was 17 years.ResultsIn the structure of initial diagnoses, according to ICD-10, mood disorders [F30-F39] - 56.0% prevailed. [F40-F49] - 25%, [F00-F09] - 6.6%, [F20-F29] - 6.6%, [F50-F59] – 4,2%, [F90-F99] – 1,6% were less likely. Structure of complaints of adolescents and their parents on primary appointment for specialized psychiatric care is shown in Table 1 (p<0,05).ConclusionsInitial signs of emotional disorders in adolescence are polymorphic, nosologically nonspecific, and can lead to diagnoses that are not limited only by the affective pathology. The most common symptoms (irritability, anxiety, mood falls) can act as transdiagnostic phenomena that must be taken into consideration both in the diagnostic study and in further clinical and dynamic follow-ups and treatment.DisclosureNo significant relationships.
Psychiatric comorbidity in a patient with opsoclonus-myoclonus syndrome. differences in the transition from childhood to adulthood: A case report
Authors: Casanovas F. , Martínez L. , Cirici R. , Dinamarca F. , García D. , Pérez A. , Diaz L. , Nascimento M.T. , Castro J.I. 
Published: February 2022

IntroductionOpsoclonus-Myoclonus syndrome (OMS), also known as Kinsbourne syndrome, is a paraneoplasic pediatric condition characterized by erratic eye movements and generalized myoclonus. Previous studies have described a wide range of psychiatric comorbidities in children with this syndrome. Cognitive impairment (especially intellectual capacity and language), affective symptoms (irritability, poor mood regulation) and behavioral problems are the most frequent presentations (1). However, there is a lack of literature describing the progression of this symptoms when the patient reaches the adulthood.ObjectivesTo illustrate the psychiatric comorbidity of an adult patient with Opsoclonus-Myoclonus syndrome.MethodsWe present one case-report and literature research of the topic.ResultsWe present a 18 year old girl diagnosed with OMS and Graves-Basedow hyperthyroidism. During her childhood she started presenting attention and comprehension difficulties. She was diagnosed with an Attention Deficit Hyperactivity Disorder (ADHD) and started treatment with methylphenidate. She completed elementary and secondary education. During the adulthood, the main psychiatric comorbidity was related to affective symptoms. We observed an impaired mood regulation, hypothymia, anhedonia, and frequent episodes of irritability, which persisted after the thyroid regulation. This caused incremented anxious symptoms and insomnia that were treated with mirtazapine and lormetazepam. After some weeks, she fulfilled criteria of a depressive episode and we started antidepressant treatment with vortioxetine.Conclusions- Adult patients diagnosed with OMS during childhood can persist presenting ADHD as a comorbidity. - Affective symptoms, and even a major depressive episode, should be considered during the follow-up of this population. Insight of the cognitive limitations could be a risk factor for a depression.DisclosureNo significant relationships.
Quarantine-related depression and anxiety during coronavirus disease (COVID-19) outbreak
Authors: Alateeq D. , Aljhani S. , Alsubaie M. , Althiyabi I. , Majzoub S. 
Published: February 2022

IntroductionPsychological well-being has an important impact on individuals. In the face of the health threat of COVID-19, psychological changes as fear stress anxiety and depression is reported.ObjectivesExplore the prevalence of depression and anxiety among people under quarantine during the COVID-19 outbreak in Saudi Arabia.MethodsA cross-sectional study of a convenience sample of 65 participants who were quarantined at multiple hotels under the supervision of the Saudi Ministry of Health. The patient health questionnaire (PHQ-9) and generalized anxiety disorder questionnaire (GAD-7) were used to assess depression and anxiety.ResultsThe majority of the participants were male (66.2%), aged 18–29 (47.7%) from the Eastern region (66.15%), who were still waiting for the result of the COVID-19 test (64.6%). Approximately half of the sample had depressive and anxiety symptoms (49.2% and 44.6%, respectively). The depression mean score was significantly higher only among the 18–29 age group. However, the depression and anxiety mean scores were higher among females than males and among participants with positive COVID-19 test results compared to those who had pending or negative results. The anxiety mean score was higher during the first week of quarantine, but the depression mean score was higher during later weeks.ConclusionsDepression and anxiety were prevalent among people in quarantine during the beginning of the COVID-19 outbreak in Saudi Arabia. It is crucial to study the most effective interventions to reduce the psychological consequences, especially for vulnerable groups. Longitudinal research studies need to be conducted to follow up regarding participants’ mental health symptoms and evidence-based interventions.DisclosureNo significant relationships.
Psychiatryteleconsultation/teleconsulting: Experience of general confinement in Tunisia
Authors: Jomli R. , Jemli H. , Ouali U. , Zgueb Y. , Nacef F. 
Published: February 2022

IntroductionThe outbreak of the Covid-19 epidemic in Tunisia has led a total confinement startingfrom March 23rd, 2020. Remote interventions of psychiatrists and psychologists have been set up to help tunisiancitizens. The requestsconcerned panic attacks, acute stress disorder, sleepdisorders and relapse of some patients followed for mooddisorders, obsessive compulsive disorder or anxietydisorders.ObjectivesWe propose to present 3 types of interventions by apsychiatrist in response to the request of 3 Tunisiancitizensin this first experience.MethodsWe will summarize three interventions with the history of each patient and his or herrequest as well as the short term evolution of the presenteddisorder.ResultsAs a first experience, weresponded to numerousrequestsfrom people of all ages and living all over Tunisia. The first intervention concerned a lady whowasvolontarilyvomiting in order to maintainhercurrentweight.Shewasafraid of having the covid infectionrelated to a sore throat. The second situation is a gentleman whodid not toleratehome confinement because for 20 yearshe has been going out for adailywalk at exactly 4 pm. The thirdrequest came from a father living in a rural area who chose to self isolate in his room and refused to go out and seehischildrendespitetheir pressing demand. We offered active listening, reassurance and behavioural psychotherapy techniques.ConclusionsDuringthis first experience in Tunisia, wefoundthatcitizens haveadhered to new communication techniques. Anxiety, stress and relapse of priormedical conditions were the mostfrequent diagnoses. Several interventions have proven to be effective despite obstacles related to teleconsultation.DisclosureNo significant relationships.
COVID-19 lockdown and its impact on mental health in various population groups in Greece: A cross-sectional study
Authors: Argyropoulos K. , Krikonis K. , Alexopoulos P. , Avramidis D. , Gourzis P. , Jelastopulu E. 
Published: February 2022

IntroductionCOVID-19 pandemic and lockdown has brought a serious impact on physical and mental health.ObjectivesThe purpose of the present study was to estimate the impact of the first lockdown in Greece, on both quality of life and anxiety levels in different occupational groups.MethodsA cross-sectional on- line survey was conducted from 20th of April to 4th of May 2020. A 24-item anonymous questionnaire was administered to collect basic demographic and socioeconomic data. The 5-item WHO Well-Being Index (WHO-5, 0-100%, cut-off 52%) and the Generalized Anxiety Disorder Assessment (GAD-7) tools were used to assess well-being and anxiety, respectively. Statistical analysis was performed with SPSS for Windows v.24.0 Statistical Package.ResultsA total of 575 participated in the study, 62.8% females, 48.5% aged between 40 to 59 years. 32.5% were employed in education sector, 32.5% in health sector and 20.3% as season workers in tourism sector. Males showed slightly higher levels of wellbeing (52.1 vs. 47.3, p=0.023) and lower levels of anxiety (7.1 vs. 8.2, p=0.023) compared to females. Factors associated with higher wellbeing and lower anxiety were higher education and income level, optimism, taking less protection measures, and being seasonal worker. Furthermore, participants with comorbidities and symptoms like headache, musculoskeletal pain, as well as feeling depressed or stressed revealed lower wellbeing and higher anxiety scores.ConclusionsOur study revealed an overall poor wellbeing and mild to moderate levels of anxiety during the lockdown. Actions should be taken to address and to prevent its serious impact on mental health.DisclosureNo significant relationships.
The effect of views on the COVID-19 pandemic on the development of depressive symptoms in a sample of the elderly
Authors: Mentis M. , Lamprinakou I. , Marneras C. , Garantoudi A. , Dritsas I. 
Published: February 2022

IntroductionThe covid-19 virus pandemic is another risk factor not only for the lives of older people, but also for their mental health, as the threat is immediate and intense.ObjectivesThe aim of the study was to investigate depression during the pandemic in a population of elderly people over 65 years of age living in the Greek countryside.MethodsThe research was synchronous and was conducted in the autumn of 2020 in Crete. The sample of the study was random and consisted of 200 elderly users of services of the Health Center of the Municipality of Phaistos, Crete. The Geriatric Depression Scale (GDS-15) was used to conduct the study in combination with 24 questions related to pandemic perceptions.Results40.5% of the sample were men and 59.5% were women. The mean age was 75.70 years (SD ± 6.29). The mean value of GDS-15 was found to be 5.97 (SD, 3.07), while the comparison of depressive symptoms showed that women, lonely people and the elderly with chronic health problems are more vulnerable to the development of depressive symptoms. In relation to covid-19 and depressive symptoms, there was a positive correlation with twelve factors (p <, 05) with the most important being the fear for their family health, sleep disorder, loneliness and inability to deal with the virus.ConclusionsThe research showed moderate depressive symptoms, while a clear effect of the pandemic due to Covid-19 was found on the emotional mood of the elderly, a fact that makes their psychosocial support necessary.DisclosureNo significant relationships.
Psychotic relapse from COVID-19 pandemic: Clinical features
Authors: Brahmi L. , Ammar H. Ben , Khelifa E. , Hamdi G. , Felhi R. , Mnif L. 
Published: February 2022

IntroductionThe COVID-19 pandemic affected today more than 76,000,000 worldwide, and more than half of humanity has been placed in quarantine. This pandemic affects mental health problems and influences the onset of symptoms.ObjectivesThe aim of this review is to analyze the impact of the COVID-19 pandemic on psychotic disorders and its interaction with the various risk factors.MethodsWe undertook a review of the impact of COVID-19 pandemic on psychosis. We carried out a systematic review of electronic databases using the keywords “COVID-19”, “pandemics”, “psychotic disorders”, and “delusions”. Relevant literature was limited to articles conducted around the world and published between January and December 2020.ResultsWe identified ten papers addressing incident cases of psychosis relapse linked to coronavirus pandemic. In multiple cases, psychotic symptoms were characterized by delusional thoughts about being infected by the coronavirus. The limited access to regular medications and psychosocial interventions was the main factor to psychotic relapse. This review included one cross-sectional clinical study comparing the impact of this pandemic on patients suffering from severe mental illness compared with healthy controls and they found that patients with mental disorders reacted to the pandemic and the lockdown restrictions with higher anxiety levels than the general public. Our study also revealed that elderly people suffering from psychosis and other chronic illness were the most vulnerable to relapse.ConclusionsPsychotic disorders can relapse during stressful events like COVID-19 pandemic. Therefore, specific attention to these vulnerable subjects is crucial to prevent relapses in times of worldwide pandemic.DisclosureNo significant relationships.
Culture and personality disorders-a case series
Authors: Iñiguez I. Cuevas , Lietor M.D.C. Molina , Alonso I. Moreno 
Published: February 2022

IntroductionPersonality disorders comprise a set of diagnosis characterized by inflexible, pervasive and enduring patterns of cognition, affect, behavioural and social interaction. The status of research on the personality among different cultures implies the universality of traits and disorders, as well as, their measuresacross cultures.ObjectivesTo study the prevalence of personality disorders in foreigner patients.MethodsIn this retrospective case series, clinicaldata was collected from 40 patients who were hospitalized at the short-stay inpatient psychiatric service of the Príncipe de Asturias University Hospital during 2018.ResultsNineteen (47.5%) patients were European, ten (25%) were from South America, nine (22.5%) were Africanand two (5%) were Asian. Eight patients were diagnosed of diverse personality disorders. Seven (87.5%) of them were European, and only one (12.5%) was from South America.ConclusionsThis case series suggests various directions for future research. The fact that patients diagnosed with personalitydisorders were mainly European could indicate diverse conclusions. It would question the universality of personality disorders out of a Euro-american frame of reference. It would also point out the difficulty of diagnosing personality disorders, taking into consideration language, awareness of cultural values,traditions, interactional patterns, and social norms. More studies of traits and personality are needed, taking into account the culture and the society in which patients have grown and in which they currently live.DisclosureNo significant relationships.
Two-eyed seeing as a philosophy to facilitate communication between traditional indigenous cultural practitioners with psychiatry and other mental health practitioners
Authors: Mehl-Madrona L. , Mainguy B. 
Published: February 2022

IntroductionA communication gap exists between psychiatry and indigenous people about views of mind and mental health, which often becomes an obstacle to optimal care and a source of distrust.ObjectivesWe aimed to explore the utility of the concept of two-eyed seeing for facilitating communication among traditional cultural practitioners (TCP) and conventional mental health practitioners (CMHP).Methods
“Two-eyed seeing” is spreading across North America as a metaphor for explanatory pluralism. Albert Marshall, a M’iqmaq from Nova, Scotia, Canada, developed this traditional concept (eptuamptamuk in M’iqmaq) to speak to the idea that indigenous knowledge is as valid as contemporary science for conceptualizing phenomena. We taught the concept to 100 practitioners, equally balanced between CMHP’s and TCP’s, and obtained ongoing feedback about the results of their applying these ideas to their ongoing collaborations. Qualitative research methods were used to evaluate this feedback.ResultsUsing the two-eyed seeing concept allowed CMHP’s to better listen to TCP’s descriptions of their concepts of mind and of mental suffering. TCP’s felt more respected by CMHP’s. While concepts such as spirit visitation, the breaking of taboos, and intergenerational curses are inherently foreign to CMHP’s, the two-eyed seeing concept allowed them to bracket these ideas as interesting and to interact with the TCP in a more productive way, while allowing them to observe the effects of the TCP’s interventions in a less judgmental way.ConclusionsTwo-eyed seeing allowed a rich dialogue between CMHP’s and TCP’s that enabled each to appreciate the other’s perspectives, leading to greater cooperation and collaborative treatment. Outcomes improved.DisclosureNo significant relationships.
Biochemical markers of depression - an up-to-date review
Authors: Nobis A. , Zalewski D. , Dąbrowska E. , Waszkiewicz N. 
Published: February 2022

IntroductionDepression or Major Depressive Disorder (MDD) is the most prevalent psychiatric disorder and a leading cause of disability worldwide. Currently affecting around 300 million people worldwide, depression is a major clinical, emotional, and socioeconomic strain for society. There is a growing interest in the biological underpinnings of depression, which are reflected by altered levels of biomarkers.ObjectivesThe aim of the study was to present an up-to-date review of potential MDD biomarkers.MethodsPubMed, Scopus, and Web of Science databases were searched.ResultsEnhanced inflammation has been reported in MDD, as reflected by increased concentrations of inflammatory markers –
interleukin-6, C-reactive protein, tumor necrosis factor-α, and soluble interleukin-2 receptor. Dysregulation of the hypothalamus-pituitary-adrenals axis, along with increased cortisol levels, have also been reported in MDD. Oxidative and nitrosative stress also plays an important role in the pathophysiology of MDD. Notably, increased levels of lipid peroxidation markers are characteristic of MDD. Kynurenine metabolites, increased glutamate and decreased total cholesterol are also features of MDD. Finally, alterations in growth factors, with a significant decrease in brain-derived neurotrophic factor and an increase in fibroblast growth factor-2 and insulin-like growth factor-1 concentrations have also been found in MDD.ConclusionsA group of substances holds promise as reliable biomarkers for MDD. However, biomarker research in depression faces many difficulties, such as insufficient understanding of MDD etiopathogenesis, substantial heterogeneity of the disorder and low specificity of biomarkers. The construction of biomarker panels and their evaluation with use of new technologies may have the potential to overcome the above mentioned obstacles.DisclosureNo significant relationships.
The prevalence of depressive disorders among young people in europe: A systematic review and meta-analysis
Authors: Sacco R. , Camilleri N. , Umla-Runge K. 
Published: February 2022

IntroductionThis systematic review estimates the pooled prevalence (PP) of depressive disorders (DD) among 5-to-18-year-old YP living in Europe, based on prevalence rates established in the last five years (LFY).ObjectivesTrends of prevalence rates across countries, gender and level of education were analysed. The random effects pooled prevalence rate (REPPR) for DD was calculated.MethodsA search strategy was conducted on three databases. Studies were also identified from reference lists and grey literature. Eligible studies were evaluated for reliability, validity, bias, and the REPPR for DD was calculated.ResultsThe European REPPR for DD is calculated at 2.0% (95%CI: 1.0%-4.0%). (Figure 1). The REPPR for each depressive disorder is shown in Figure 1. The prevalence among secondary school children is 4.2 times higher than that among primary school children.ConclusionsRoutine screening and early intervention strategies for eating disorders may improve the outcome of young people with these problems.DisclosureNo significant relationships.
The role of travel for people with an eating disorder, an optimal leisure experience
Authors: Mostefa-Kara L. 
Published: February 2022

IntroductionProject-based leisure would be conducive to enabling people to project themselves into the future and to move away from the eating disorder, which involves a constant preoccupation with food and one’s body. According to this, travel could be a leisure opportunity that invites to challenge oneself by going out of one’s comfort zone. Coping is a real dilemma for people living with eating disorders and the motivations of a tourism experience could refer to motivation to leave one’s current environment. Consequently, travel would be helpful in reducing the individual’s focus on the illness in a different environment.Objectives
The aim of this study is to investigate the use of travel to help people living with eating disorders to live in the present moment and to “let go”. Then, to understand what are the components of travel that are essential for an optimal leisure experience.MethodsThis multiple case study uses mixed data from a sample of five participants with an ED and living in France. They were invited to live a tourism experience in Québec for one week. This data collection was before, during and after the trip, using the Experience Sampling Method with a mobile app pocket and guided interviews to assess sensations and emotions in the ecological context of patients.ResultsThe trip allowed a letting go and developed a greater ability to live in the present moment. It was a significantly positive moment in the lives of the participants.ConclusionsTravel associate with digital diary are an innovative approach for ED.DisclosureNo significant relationships.
Influence of precipitation on psychiatric emergency care visits
Authors: Hernández-Calle D. , Bravo-Ortiz M.F. 
Published: February 2022

IntroductionPsychiatric emergency care visits have been associated to several climate variables. However, the influence of precipitation has been understudiedObjectivesTo study the association between precipitation and number of emergency care psychiatric visits.MethodsDaily urgency visits were extracted from electronic medical records of Hospital Universitario La Paz from 1st January 2019 to 31th December 2019. Precipitation data (measured as accumulated litres per square meter) was obtained from a local climate station. Spearman correlation was estimated.ResultsThe Spearman correlation coefficient was -0.02(p = 0.80).ConclusionsPrecipitation was not associated to number of emergency visits.DisclosureNo significant relationships.