bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pantoea
Authors: Palmer Marike , Coutinho Teresa A. 
Published: March 2022

Abstract

Pan.toe'a. Gr. masc. adj.
pantoios
, of all sorts and sources; N.L. fem. n.
Pantoea
, [bacteria] from diverse [geographical and ecological] sources.

Pseudomonadota / Gammaproteobacteria / Enterobacterales / Enterobacteriaceae / Pantoea

The genus
Pantoea
comprises a versatile assemblage of Gram‐negative and facultatively anaerobic bacteria. These bacteria occur in association with plant and animal hosts, as beneficial or pathogenic members of the communities or as free‐living in various environments. Cells of the members of this genus are non‐spore‐forming and nonencapsulated rods, ranging between 0.5 and 1.3 by 1.0 and 3.8 μm. The formation of symplasmata occurs in some members of the genus. Most are motile by means of peritrichous flagella, with some members producing a yellow pigment. The genus currently consists of 23 validly and effectively published species, ranging widely in isolation source and apparent pathogenic ability. The genomes of these organisms range markedly in size, with the median genome size being 4.85 Mb. The genomic pool of these organisms is diverse, contributing to their ecological versatility. Conserved genes within the genus are mainly involved in core housekeeping functions. This genus forms part of the family
Enterobacteriaceae
, with a close evolutionary relationship to
Erwinia
,
Izhakiella
,
Mixta
,
Phaseolibacter
,
Rosenbergiella
, and
Tatumella
. The G + C content of their DNA, as determined from genome sequences, ranges between 51.80 and 59.60%. Various members of this genus are considered pathogens or opportunistic pathogens, while some isolates display biotechnological and agricultural potential.

DNA G + C content based on genome (mol%)
: 51.90–59.60.

Type species
:
Pantoea agglomerans
(Beijerinck 1988) Gavini et al. 1989
VP
.
Moraxella
Authors: Fernández‐Garayzábal José Francisco , Miguela‐Villoldo Pedro , Vela Ana Isabel 
Published: March 2022

AbstractMo.ra.xel'la. N.L. dim. fem. n.Moraxella, named after V. Morax, a Swiss ophthalmologist who pioneered the recognition of the type species.Proteobacteria / Gammaproteobacteria / Pseudomonadales / Moraxellaceae / MoraxellaMoraxellaspecies are Gram‐negative rods or cocci but often with a tendency to resist decolorization. The rods are often very short and plump, frequently approaching a coccus shape (1.0–1.5 × 1.5–1.5 μm); they usually occur in pairs and short chains. Variation in cell size, shape, and filament or chain formation is often seen in cultures, the pleomorphism being enhanced by lack of oxygen and by incubation temperatures above the optimum. The cocci are usually smaller (0.6–1.0 μm in diameter) and occur as single cells or in pairs; sometimes results in the formation of tetrads. Flagella are absent. Both coccal and rod‐shaped species can be fimbriated. Absence of swimming motility, but surface‐bound “twitching motility” has been observed in some rod‐shaped species. Aerobic, but some species can grow weakly under anaerobic conditions. May be encapsulated. Chemoorganotrophic. Most species are nutritionally fastidious, and all grow in complex media; some are stimulated significantly by fatty acids (bile salts and Tween 80). The optimal temperature for growth is between 33 and 35°C. Colonies are not pigmented. Oxidase‐positive. Usually catalase‐positive. No acid is produced from carbohydrates. Species of this genus share 96–99% similarity in their 16S rRNA gene sequences. The major fatty acids in most species are C18 :1ω9cand C16:1ω7c. The major quinone is Q‐8. Members of the classGammaproteobacteriaand familyMoraxellaceae. Parasitic on the mucous membranes of humans and other warm‐blooded animals.DNA G + C content (mol%): 40–48.1 (Tm, Bd, HPLC).Type species:Moraxella lacunataLwoff 1939AL, synonym: “Bacillus lacunatus” Eyre 1900.
Parapusillimonas
Authors: Durán‐Viseras Ana , Manaia Célia M. , Vaz‐Moreira Ivone , Nunes Olga C. 
Published: March 2022

Abstract

Parapusillimonas
(Pa.ra.pu.sil.li.mo'nas. Gr. prep.
para
like; N.L. fem. n.
Pusillimonas
bacterial genus name; N.L. fem. n.
Parapusillimonas
a bacterium like
Pusillimonas
).

Proteobacteria / Betaproteobacteria / Burkholderiales / Alcaligenaceae / Parapusillimonas

Gram‐staining‐negative motile short
rods
, with
three flagella
. Facultatively anaerobic. Catalase‐ and cytochrome
c
oxidase‐positive.
Chemoorganotrophic
. Sugar, alcohols, organic acids, and amino acids can be used as single carbon sources.
Ubiquinone 8
is the major respiratory quinone, and the predominant fatty acids are
C

16:0

,
summed feature 3
(C
16:1
ω7
c
/C
15:0
iso 2‐OH),
C

17:0

cyclo
, and
summed feature 5
(C
18:1
ω7
c
/ω9
t
/ω12
t
). The major polar lipids are
phosphatidylethanolamine
,
phosphatidylglycerol
, and
diphosphatidylglycerol
.
Putrescine
is the major polyamine.

DNA G + C content (mol%)
: 67.9 (HPLC) and 64.6 (genome).

Type species
:
Parapusillimonas granuli
Kim et al. 2010
VP
.
Pusillimonas
Authors: Durán‐Viseras Ana , Manaia Célia M. , Vaz‐Moreira Ivone , Nunes Olga C. 
Published: March 2022

Abstract

Pusillimonas
(Pu.sil.li.mo'nas. L. masc. adj.
pusillus
very small/minute; Gr. fem. n.
monas
unit/monad; N.L. fem. n.
Pusillimonas
very small monad/unicell, referring to the small size of cells and colonies of the type species).

Proteobacteria / Betaproteobacteria / Burkholderiales / Alcaligenaceae / Pusillimonas

Rods
, Gram‐stain‐negative, and nonmotile or motile by polar or lateral flagella. Strictly
aerobic
. The optimal growth temperature range is 30–37°C. Catalase and cytochrome
c
oxidase tests are positive in most species. The major respiratory quinone is
ubiquinone Q‐8
. The cellular fatty acid composition is characterized by the predominance of C
16:0
. The other most abundant fatty acids (C
17:0
cyclo, C
19:0
cyclo ω8
c
, and C
18:0
) vary among species. The polar lipids composition comprises phosphatidylglycerol, diphosphatidylglycerol, and phosphatidylethanolamine as well as some unidentified amino‐ and phospholipids. Phylogenetically, belongs to the family
Alcaligenaceae
.

DNA G + C content (mol%)
: 53.1–63.3 (
T
m
/HPLC) and 53.4–63.1 (WGS).

Type species
:
Pusillimonas noertemannii
Stolz et al. 2005
VP
.
Planctomicrobium
Authors: Dedysh Svetlana N. , Ivanova Anastasia A. , Kulichevskaya Irina S. 
Published: March 2022

Abstract

Planctomicrobium
(Planc.to.mi.cro'bi.um. Gr. masc. adj.
planktos
, wandering, floating; N.L. neut. n.
microbium
, (from Gr. masc. adj.
mikros
small and Gr. masc. n.
bios
life) a microbe; N.L. neut. n.
Planctomicrobium,
floating microbe).

Planctomycetes / Planctomycetia / Planctomycetales / Planctomycetaceae / Planctomicrobium

The genus
Planctomicrobium
is represented by bacteria with Gram‐negative, ellipsoidal to pear‐shaped, and nonpigmented cells that occur singly, in pairs, in small rosettes, or in aggregates. Free cell poles are covered with crateriform pits. Cell division occurs by means of budding; buds arise from the free cell pole of the mother cells. Daughter cells are motile by means of a polar flagellum, while mature cells are immobile and possess stalks. These bacteria are aerobic chemoorganotrophs, which utilize monomeric sugars and some polysaccharides. The two currently characterized strains are capable of growth on chitin. Mildly acidophilic and mesophilic. Sensitive to NaCl; do not develop at NaCl concentrations above 0.5 (w/v). The major quinone is MK‐6. The major fatty acids are C
16:0
and C
16:1
ω7
c
. The major polar lipids are diacylglycerol‐
O‐
(
N
,
‐N
,
‐N
‐trimethyl)homoserine lipids; the major neutral lipids are long‐chain 1,(ω‐1)‐diols. The genus belongs to the phylum
Planctomycetes
, class
Planctomycetia,
order
Planctomycetales
, and family
Planctomycetaceae
. The type species is
Planctomicrobium piriforme
. Representatives of this genus colonize various freshwater habitats.

DNA G
+
C content
(
mol
%): 58.8 (genome sequence).

Type species
:
Planctomicrobium piriforme
Kulichevskaya et al. 2015
VP
emend. Kulichevskaya et al. 2019.
Progressive choreodystonia in X‐linked hyper‐IgM immunodeficiency: a rare but recurrent presentation
Authors: Škorvánek Matej , Jech Robert , Winkelmann Juliane , Zech Michael 
Published: March 2022

AbstractAn association between movement disorders and immune‐system dysfunction has been described in the context of rare genetic diseases such as ataxia telangiectasia as well as infectious encephalopathies. We encountered a male patient who presented immunodeficiency of unknown etiology since childhood. A medication‐refractory, progressive choreodystonic movement disorder emerged at the age of 42 years and prompted an exome‐wide molecular testing approach. This revealed a pathogenic hemizygous variant in CD40LG, the gene implicated in X‐linked hyper‐IgM syndrome. Only two prior reports have specifically suggested a causal relationship between CD40LG mutations and involuntary hyperkinetic movements. Our findings thus confirm the existence of a particular CD40LG‐related condition, combining features of compromised immunity with neurodegenerative movement abnormalities. Establishing the diagnosis is crucial because of potential life‐threatening immunological complications.
Assembly of Metal–Phenolic Networks on Water‐Soluble Substrates in Nonaqueous Media
Authors: Mazaheri Omid , Alivand Masood S. , Zavabeti Ali , Spoljaric Steve , Pan Shuaijun , Chen Deli , Caruso Frank , Suter Helen C. , Mumford Kathryn A. 
Published: March 2022

AbstractInterfacial modular assemblies of eco‐friendly metal–phenolic networks (MPNs) are of interest for surface and materials engineering. To date, most MPNs are assembled on water‐stable substrates; however, the self‐assembly of MPNs on highly water‐soluble substrates remains unexplored. Herein, a versatile approach is reported to engineer thickness‐tunable coatings (2–25 µm) on a water‐soluble substrate (i.e., urea) via the self‐assembly of MPNs in a nonaqueous solvent (i.e., acetonitrile). The coordination‐driven assembly of the MPN coatings in the nonaqueous solvent is distinct from that in aqueous systems, as the assembly is only achieved following the addition of urea granules into the iron–tannin solution. The coating occurs relatively rapidly (5–60 min), generating micrometer‐thick coatings from the adsorption of FeIII–TA complexes and micrometer‐sized FeIII–TA particles formed in solution. The straightforward nature of the present fabrication method in generating thick and robust coatings with high stability in nonaqueous environments (including at 60 °C) coupled with the broad range of available naturally abundant polyphenol–metal ion combinations expand the applicability of MPNs as coatings for water‐soluble materials, thus providing new opportunities for their broader application in a range of industrial processes and applications.
Biomimetic Immunosuppressive Exosomes that Inhibit Cytokine Storms Contribute to the Alleviation of Sepsis
Authors: Li Yinan , Zhang Heng , Chen Caihong , Qiao Kailiang , Li Zhiyang , Han Jingxia , Han Xu , Li Kun , Lai Keguan , Liu Ning , Li Ang , Xiao Nannan , Zhang Yan , Zhao Xiangshuai , Gao Wenqing , Zhang Yang , Liu Huijuan , Sun Tao 
Published: March 2022

AbstractSepsis is a disease characterized by multiple organ failure caused by immune hyperactivation and cytokine storms. Studies have shown that the incidence of sepsis in melanoma patients is substantially lower compared to the general population. It is also observed that experimental tumor‐bearing animals have high survival rates after sepsis induction, suggesting that tumors may suppress sepsis‐associated immune overactivation, thereby alleviating sepsis. Based on the above‐described findings, this work assesses whether tumor cells play an antisepsis role in mice through the secretion of exosomes. Analysis of exosome activity reveals that the induced exosomes (iExo) secreted by tumor cells following lipopolysaccharide (LPS) treatment improve sepsis to a greater extent than normal secretory exosomes. Further analysis reveals that iExo exert their protective effects mainly through seven key miRNAs. In vitro bionic simulation of exosomes is carried out using exosome mimics generated by loading the aforementioned microRNAs into hyaluronic acid–polyethylenimine nanoparticles. Exosome mimics at specific miRNA ratios alleviate sepsis in mice and cynomolgus monkeys, indicating that biomimetic simulation of tumor‐suppressive exosomes may represent a promising therapeutic method for the treatment of sepsis and cytokine‐storm‐related conditions.
A Wearable PVA Film Supported TiO2 Nanoparticles Decorated NaNbO3 Nanoflakes‐Based SERS Sensor for Simultaneous Detection of Metabolites and Biomolecules in Human Sweat Samples
Authors: Durai Lignesh , Badhulika Sushmee 
Published: March 2022

AbstractSweat is one of the non‐invasive diagnostic biofluids that provides critical information about human health. In this work, a wearable sweat sensor integrated with a polymer‐based fluid absorption layer modified with titanium oxide (TiO2) nanoparticles decorated sodium niobate (NaNbO3) nanoflakes in porous polyvinyl alcohol (PVA) film matrix is demonstrated for the detection of vital metabolites (such as glucose and urea) and biomolecules (ascorbic acid (AA) and uric acid (UA)) in human sweat samples via surface‐enhanced Raman scattering (SERS). The TiO2@NaNbO3/PVA (SERS patch) exhibits a low limit of detection (LOD) of 0.50, 0.80, 1.00, and 100 mm towards AA, glucose, UA, and urea, respectively. The SERS patch displays a high enhancement factor with a low accumulation time of 20s which can be ascribed to the surface coordination between the TiO2@NaNbO3 and the analytes leading to interfacial charge‐transfer transition (ICTT). Besides, the photo‐induced charge transfer (PICT) resonance significantly amplifies the SERS signal. The SERS patch is successful in the simultaneous determination of AA, glucose, UA, and urea in simulated sweat samples with minimal mutual interference. The high efficacy of the SERS patch proves it as an ideal platform for a wide range of wearable healthcare monitoring applications.
A Pocket‐Sized Ten‐Channel High Voltage Power Supply for Soft Electrostatic Actuators
Authors: Mitchell Shane K. , Martin Trent , Keplinger Christoph 
Published: March 2022

AbstractAs soft electrostatic actuators find applications in bio‐inspired robotics, compact and lightweight high voltage electronics that independently address many actuators are required. Here, a pocket‐sized, battery‐powered, 10‐channel high voltage power supply (HVPS) is presented, which independently addresses each channel up to 10 kV. The HVPS uses one HV amplifier to create a HV rail and each output connects to the rail via custom optocouplers that are pulse‐width modulated to vary their conductance. These optocouplers distribute charges to and from electrostatic devices at each output, creating a charge‐controlled driving scheme that can generate independent and nearly arbitrary actuation waveforms for each channel. The HVPS weighs 250 g and measures 8.4 cm × 13.3 cm × 2 cm, about the size of a smartphone. The HVPS is characterized when driving hydraulically amplified self‐healing electrostatic (HASEL) actuators. While powering a 5 nF actuator, the output of the HVPS reaches 8 kV in 100 ms and drives a 1.5 nF actuator at 100 Hz (0 to 5.4 kV). The HVPS powers an active surface consisting of an array of HASELs and generates undulatory locomotion of a soft robotic inchworm, highlighting the potential for compact HV electronics that power multi‐degree‐of‐freedom robotic systems based on electrostatic devices.
MXene‐Polymer Hybrid for High‐Performance Gas Sensor Prepared by Microwave‐Assisted In‐Situ Intercalation
Authors: Zhou Jin , Hosseini Shokouh Seyed Hossein , Komsa Hannu‐Pekka , Rieppo Lassi , Cui Linfan , Lv Zhong‐Peng , Kordas Krisztian 
Published: March 2022

Abstract2D transition‐metal carbides (Ti3C2Tx MXene) intercalated with organic molecules have been widely used in batteries and supercapacitors, but are quite rarely reported for gas sensing. Since Ti3C2Tx is sensitive to oxygen, most methods for preparing the intercalated Ti3C2Tx involve stirring the reactants with Ti3C2Tx for several hours under nitrogen protection. Herein, a method to prepare a hybrid of Ti3C2Tx and intercalated polysquaraine through microwave‐assisted in situ polymerization that takes only a few minutes without the need of using a protective atmosphere is demonstrated. Owing to the increased interlayer space of the Ti3C2Tx after the polymerization, the gas sensors based on the hybrid exhibit a good sensing performance for NH3 detection, being able to detect at least 500 ppb NH3 with a 2.2% ppm−1 of sensitivity. This study provides a facile preparation method for developing intercalated MXenes, which are expected to be useful for a wide range of applications.
Ni2+‐Directed Anisotropic Growth of PtCu Nested Skeleton Cubes Boosting Electroreduction of Oxygen
Authors: Zhang Yafeng , Ye Kai , Liu Qianru , Qin Juan , Jiang Qike , Yang Bing , Yin Feng 
Published: March 2022

AbstractStructure‐controlled Pt‐based nanocrystals have the great potential to provide a flexible strategy for improving the catalysis of the oxygen reduction reaction (ORR). Here, a new synthetic approach is developed to tune the 3D structure of Pt‐based alloys, and switch a synthetic reaction which produces solid PtCu octahedral stars (OSs) to produce PtCu nested skeleton cubes (NSCs) by simple addition of Ni(acac)2. In particular, Ni2+‐guided anisotropic growth is observed to generate the nested skeleton structure in PtCu NSCs. Ni2+, though absent from the nanoalloys, not only endows faster Cu reduction kinetics but also acts as a structure‐directing agent. Moreover, it is shown that acetic acid treatment of PtCu NSCs/C exposes Pt‐rich surface with a fine‐tuned Pt d‐band center energy and the reduced Cu leaching, resulting in strikingly high activity and stability. Acid‐treated PtCu NSCs/C shows a remarkable ORR mass activity of 5.13 A mgPt–1, about 26 times higher than commercial Pt/C catalyst. This catalyst also exhibits excellent stability with a lower activity decay of 11.5% and the negligible variation in structure after 10 000 cycles.
Ir Single Atom Catalyst Loaded on Amorphous Carbon Materials with High HER Activity
Authors: Liu Chunxiang , Pan Ganghuo , Liang Nianjie , Hong Song , Ma Jingyuan , Liu Yuzhou 
Published: March 2022

AbstractThe research of high efficiency water splitting catalyst is important for the development of renewable energy economy. Here, the progress in the preparation of high efficiency hydrogen evolution reaction (HER) catalyst is reported. The support material is based on a polyhexaphenylbenzene material with intrinsic holes, which heals into carbon materials upon heating. The healing process is found to be useful for anchoring various transition metal atoms, among which the supported Ir Single‐atom catalyst (SAC) catalyst shows much higher electrocatalytic activity and stability than the commercial Pt/C and Ir/C in HER. There is only 17 mV overpotential at 10 mA cm–2, which is significantly lower than that of commercial Pt/C and Ir/C catalysts respectively by 26 and 3 mV, and the catalyst has an ultra‐high mass activity (MA) of 51.6 at 70 mV potential and turn over frequencies (TOF) of 171.61 s–1 at the potential of 100 mV. The density functional theory (DFT) calculation reveals the significant role of carbon coordination around the Ir center. A series of monatomic PBN‐300‐M are synthesized by using of designed carbon materials. The findings provide an enabling and versatile platform for facile accessing SACs toward many industrial important reactions.
Coupling Lipid Labeling and Click Chemistry Enables Isolation of Extracellular Vesicles for Noninvasive Detection of Oncogenic Gene Alterations
Authors: Sun Na , Tran Benjamin V. , Peng Zishan , Wang Jing , Zhang Ceng , Yang Peng , Zhang Tiffany X. , Widjaja Josephine , Zhang Ryan Y. , Xia Wenxi , Keir Alexandra , She Jia‐Wei , Yu Hsiao‐hua , Shyue Jing‐Jong , Zhu Hongguang , Agopian Vatche G. , Pei Renjun , Tomlinson James S. , Toretsky Jeffrey A , Jonas Steven J. , Federman Noah , Lu Shaohua , Tseng Hsian‐Rong , Zhu Yazhen 
Published: March 2022

AbstractWell‐preserved molecular cargo in circulating extracellular vesicles (EVs) offers an ideal material for detecting oncogenic gene alterations in cancer patients, providing a noninvasive diagnostic solution for detection of disease status and monitoring treatment response. Therefore, technologies that conveniently isolate EVs with sufficient efficiency are desperately needed. Here, a lipid labeling and click chemistry‐based EV capture platform (“Click Beads”), which is ideal for EV message ribonucleic acid (mRNA) assays due to its efficient, convenient, and rapid purification of EVs, enabling downstream molecular quantification using reverse transcription digital polymerase chain reaction (RT‐dPCR) is described and demonstrated. Ewing sarcoma protein (EWS) gene rearrangements and kirsten rat sarcoma viral oncogene homolog (KRAS) gene mutation status are detected and quantified using EVs isolated by Click Beads and matched with those identified in biopsy specimens from Ewing sarcoma or pancreatic cancer patients. Moreover, the quantification of gene alterations can be used for monitoring treatment responses and disease progression.
Social care practices and perspectives among U.S. pediatric emergency medicine fellowship programs
Authors: Assaf Raymen Rammy , Barber Doucet Hannah , Assaf Ryan David , Graff Danielle 
Published: March 2022

AbstractBackgroundThe emergence of social emergency medicine—the incorporation of social context into the structure and practice of emergency care—has brought forth greater embracement of the social determinants of health by medical professionals, yet workforce practices and training have remained elusive. Academic literature particularly in the field of pediatric emergency medicine (PEM) fellowship training is lacking relative to general pediatrics and adult emergency medicine.MethodsThe primary objective of this study was to assess the social care knowledge, perspectives, and training of PEM program directors (PDs) and fellows across a national cross‐sectional sample. A secondary aim was to uncover key actionable areas for the development of social care curricula in PEM training programs. A social care practices assessment tool was developed via snowball sampling interviews among clinician researcher experts and disseminated to PEM PDs and fellows nationally in accredited academic PEM training institutions.ResultsA total of 153 participants—44 PDs (49% response rate) and 109 fellows (28%)—completed the assessment tool. Responses among PDs and fellows were highly concordant. Only 12% reported regular use of a standardized social needs screening tool. The majority felt unprepared to assist families with social needs and less than half felt comfortable talking to families about social need. At the same time, social care was highly valued by 73% of participants. All participants felt that providing social care training during PEM fellowship would be beneficial. PDs and fellows identified five priority areas for PEM curricular development.ConclusionsPEM PDs and fellows have an overall favorable perception of social care yet report significant deficits in current practice organization and training. This study is part of a larger national collaborative advocacy project to organize and advance social care delivery across academic PEM training institutions through evidence‐based approaches, best practices, and expert consensus.