bluuebunny/crossref_metadata_2025_split huggingface dataset:
Numerical investigation on the effect of thermal gate moving rate on directional solidification process
Authors: Su Wenjia , Guan Zhicheng , Li Jiulong , Zhang Zhen , Li Jiaqi 
Published: October 2022

Abstract
The temperature field distribution during the growth of crystalline silicon by the directional solidification (DS) method is an important factor affecting the growth rate, the shape of the melt-crystal (m-c) interface, and thermal stress. To solve the problem of m-c interface convexity at the early stage of crystal growth caused by supercooling at the bottom center of silicon ingot during DS. In this paper, a two-dimensional global transient numerical model based on a large-size ALD-G7 (G7) crystalline silicon ingot furnace is established and experimentally verified. Based on the model, the influence of different bottom thermal gate moving process curves on the convexity of the m-c interface at the early stage was studied, with emphasis on the changes in temperature field, m-c interface, and thermal stress at the early stage of crystal growth. We have designed three cases, case 1 uses the original moving process curve of bottom thermal gate, case 2 and case 3 adjust the process curve to 0.95 and 0.9 of the original ratio, respectively. The numerical results show that the center cooling condition of silicon ingot and the convexity of the m-c interface are improved with the decreasing of thermal gate moving rate. Compared with case 1, the convexity of case 2 and case 3 is reduced by 55% and 44% on average, respectively.
CircFOXK2 Promotes Hepatocellular Carcinoma Progression and Leads a Poor Clinical Prognosis via Regulating the Warburg Effect
Authors: Zheng Jun , Pan Zihao , Lu Tongyu , Song Wen , Li Yang , Liang Jinliang , Zhang Jiebin , Cai Jianye , Sui Xin , Xiao Jiaqi , Chen Haitian , Chen Guihua , Liu Yubin , Zhang Qi , Zheng Kanghong , Yang Yang 
Published: October 2022

Abstract
Background: The Warburg effect is essential for tumor progression causing poor clinical outcomes in patients with hepatocellular carcinoma (HCC). Circular RNAs (circRNAs) have emerged as important regulators for HCC. However, limited circRNAs involved in the Warburg effect of HCC have been investigated. Herein, we aimed to explore the contribution of circFOXK2 to the reprogramming of glucose metabolism of HCC.
Methods: Divergent primers were constructed to identify 14 circRNAs originating from FOXK2 gene followed by investigating their differential expression between HCC and the adjacent normal tissues (ANTs), and circFOXK2 (hsa_circ_0000817) was screened for further research. Next, the clinical significance of circFOXK2 was evaluated, coupled with evaluating its onco-promoting activity and the affection to the Warburg effect in both HCC cell lines and animal xenografts. Finally, the molecular mechanisms underlying circFOXK2 regulating the Warburg effect of HCC were explored.
Results: CircFOXK2 was aberrantly upregulation in HCC tissues, and its expression was positively correlated with poor clinical outcomes in patients receiving radical hepatectomy. Silenced circFOXK2 remarkably suppressed the progression of HCC both in vitro and in vivo. Mechanistically, circFOXK2 could not only encode a novel protein, FOXK2-142aa, to promote LDHA phosphorylation but also regulate miR-484/Fis1 pathway to lead to mitochondrial fission, which activates the Warburg effect in HCC.
Conclusions: CircFOXK2, a prognostic biomarker of the disease, exerts critical roles in promoting the Warburg effect through its roles in protein-encoding and miRNA sponges that lead to tumor progression, indicating that circFOXK2 may serve as a potential therapeutic target for patients with HCC.
Three novel Erwinia billingiae phages represent three new genera isolated from organic waste
Authors: Alanin Katrine Wacenius Skov , Olsen Nikoline S. , Djurhuus Amaru Miranda , Carstens Alexander Byth , Nielsen Tue Kjærgaard , Wagner Natalia , Lametsch René , Bak Frederik , Hennessy Rosanna Catherine , Nicolaisen Mette Haubjerg , Kot Witold , Hansen Lars Hestbjerg 
Published: October 2022

Abstract
Despite the ecological significance of viral communities, phages remain understudied. Current genomic databases lack high-quality phage genomes linked to specific bacteria. Bacteria of the Erwinia genus are known to colonize the phyllosphere of plants, both as commensals and pathogens. We isolated three Erwinia billingiae phages; Zoomie, Pecta, and Snitter from organic household waste. Based on sequence similarity to their closest relatives, we propose that they represent three new genera “Pectavirus” within the Zobellviridae family, “Snittervirus” in the subfamily Tempevirinae, family Drexlerviridae, and “Zoomievirus” within the Autographviridae family, which may constitute a yet undefined sub-family together with the genus Limelightvirus.
Four Novel Curtobacterium Phages Isolated from Environmental Samples
Authors: Alanin Katrine Wacenius Skov , Olsen Nikoline S. , Djurhuus Amaru Miranda , Carstens Alexander Byth , Nielsen Tue Kjærgaard , Rothgardt Magnus Mulbjerg , Russel Andreas Marieboe , Wagner Natalia , Lametsch Rene , Bak Frederik , Hennessy Rosanna Catherine , Nicolaisen Mette Haubjerg , Hansen Lars Hestbjerg , Kot Witold 
Published: October 2022

Abstract
Despite Curtobacterium spp. often being associated with the plant phyllosphere, i.e., the areal region of different plant species, only one phage targeting a Curtobacterium spp. has been isolated to this day. In this study, we isolated four novel plaque-forming Curtobacterium phages Reje, Penoan, Parvaparticeps, and Pize with two novel Curtobacterium strains as propagation hosts. Based on the low nucleotide intergenomic similarities (< 32.4%) between these four phages and to any published phage genomes on NCBI, we propose the four new genera “Rejevirus”, “Pizevirus”, “Penoanvirus”, and “Parvaparticepsvirus” all in the class Caudoviricetes.
Development of an Assessment Model for Soft Skills during Engineering Recruitment Process
Authors: Ribeiro Yoná Pietra , Campos Débora Barni 
Published: October 2022

Abstract
The present research work develops a prototype model to assess the soft skills for Engineers to enter the job market, developed based on consolidated psychometrics theory. The aim of the assessment model to evaluate soft skills is to improve the assertiveness of the Engineering hiring process. The theoretical support and guidelines for the elaboration of the model were obtained through a Systematic Bibliographic Review (RBS) with articles published between 2017 and 2022 within the Scopus and Science Direct databases. As a result of the work, a questionnaire with 19 soft skills identified as important for the employability of an Engineer was elaborated. The questionnaire can be used as a tool for data (both qualitative and quantitative) collection, assisting the decision-making process of employers in the Engineering area.
Probing the Structural, electronic and optical properties of pure and B, N, or Li substituted Cyclo-18 ring: Density Functional Theory Investigations
Authors: Trivedi Ravi , Garg Nandini , Jha Prafulla , Chakraborty Brahmananda 
Published: October 2022

Abstract
Employing the quantum computational approach by using the Density Functional Theory along with GGA exchange correlation functional, we have investigated the structural, electronic, and optical properties of Cyclo-18 ring containing 18 sp hybridized carbon atoms and substituted cyclo C17X (X = B, N, and Li) ring. The cyclo-18 ring has two opposite π electron system that can be organized as a D9h pollyene and D18h cumulene form. Our computational simulations suggest that D9h pollyene structure is minimum energy structure. The stability of the system has been discussed by analyzing HOMO-LUMO gap; quadrupole moments, and higher multipole moments. Pure C18 system exhibits semiconductor in nature whereas doping can tune both electronic and optical properties. There is an enhancement in optical absorption in the visible region due to doping which makes the system suitable for photo-catalytic applications. Interestingly, there is a red shift in the UV-V spectra due to doping.
The Coconut Technique: A New Method to Perform Safe Cholecystectomy for Acute Cholecystitis
Authors: TORO Adriana , MAZZONE Chiara , Fontana Emanuele Gaspare , Saverio Salomone Di , Ansaloni Luca , Catena Fausto , Carlo Isidoro Di 
Published: October 2022

Abstract
Introduction
Aim of this manuscript is to illustrate a new method permitting total cholecystectomy in terms of safety with respect to the CBD.
Methods
The core of this new technique is the identification of the continuity of the cystic duct with the infundibulum. The cystic duct is identified between internal gallbladder wall and external inflamed wall.
Results
In the last 2 years, 3 patients have been treated with the reported technique without complications.
Conclusions
Among the various cholecystectomy procedures, this is a new approach that ensures the safety of Calot’s triangle structures while providing the advantages gained from total removal of the gallbladder.
Structural Relaxation and Thermodynamics of Viscous Aqueous Systems: a simplified reappraisal
Authors: Schiraldi Alberto 
Published: October 2022

Abstract
The attainment of true equilibrium conditions is a dynamic process that encompasses a time span. For slow relaxing systems, non-equilibrium steady states can often look like equilibrium states. This is the case of viscoelastic systems, whose properties reflect their thermo-rheological history.
After a summary of the seminal woks by Eyring, Adam & Gibbs and Angell, and mention of promising recent approaches that imply updated theoretical and experimental techniques, the paper suggests a simplified approach for aqueous systems, through a modified expression of the chemical potential of water and use of the “dynamic” phase diagram, so far proposed by Slade and Levine.
For homogeneous systems (aqueous solutions), an extra term in the expression of the chemical potential accounts for the energy related to the residual strains produced during the thermo-rheological history of the system. This approach allows estimation of the effect of viscosity on the observed freezing point of polymer solutions.
For heterogeneous systems (hydro-gels, colloidal glasses), changes of the phase boundaries in the phase diagram explain the gel/sol hysteresis and the syneresis process as the result of water exchange between hosting meshes and trapped aqueous solution.
Finally, physical hurdles that hinder inter-phase water displacements and/or the access to the headspace of the system can lead to the coexistence of aqueous phases with different aW within the same heterogeneous system.
How controlled is the expansion of VIATORR CX?
Authors: Dell Tatjana , Menne Matthias , Wagenpfeil Julia , Praktiknjo Michael , Jansen Christian , Isaak Alexander , Mesropyan Narine , Steinseifer Ulrich , Attenberger Ulrike , Luetkens Julian , Meyer Carsten , Kuetting Daniel 
Published: October 2022

Abstract
Purpose: To investigate and compare the physical properties of the new generation Gore VIATORR Controlled Expansion Endoprothesis (VCX) to those of the predecessor VIATORR stent in an in vitro experimental setup.
Materials and Methods: A total of 12 stents (8 VCX; 4 VIATORR; GORE, Flagstaff USA) were examined. Radial resistive force (RRF) and chronic outward force (COF) were assed using a radial force testing machine (RX-650, Machine Solutions Inc., Flagstaff, AZ, USA). To assess the radial forces of the VCX above 8 mm, balloon expansion was performed between cycles.
Results: All VCX stents show an abrupt decrease in COF at an external diameter of 8.3 mm; RRF decreases over-proportionally at an external diameter of 8.5 mm. The predecessor VIATORR stent without the “controlled expansion” feature shows linear radial force reduction until full expansion at a diameter of 10 mm.
The physical properties of the VCX can be altered by balloon modulation. Point of COF (RRF) reduction shifts to 8.5 mm (8.6 mm), 8.6 mm (8.8 mm) and 9.3 mm (9.6 mm) following modulation with a 8 mm, 9 mm and 10 mm balloon.
Conclusions: The VCX shows an abrupt and overproportional decrease of COF and RRF at an external diameter of 8.3 mm, thus passive expansion to its’ nominal diameter of 10 mm is not to be expected. By means of balloon dilatation the physical properties of the stent can be altered, enabling customized TIPS creation. The previous VIATORR stent shows continuous COF and RRF.
Regularized Linear Discriminant Analysis Via A New difference-of-convex algorithm with extrapolation
Authors: Wang Chunyan , Wang Wenjie , Li Mengzhen 
Published: October 2022

Abstract
In this paper, we transform the classical linear discriminant analysis (LDA) into a smooth difference-of-convex optimization problem. Then, a new difference-of-convex algorithm with extrapolation is introduced and the convergence of thealgorithm is established. Finally, for face recognition problem, the proposed algorithm achieves betterclassification performance compared with several current algorithms in the literature.
AMS Subject Classification: 15A18; 15A69
Computing Longest Lyndon Subsequences and Longest Common Lyndon Subsequences
Authors: Bannai Hideo , I Tomohiro , Kociumaka Tomasz , Köppl Dominik , Puglisi Simon J. 
Published: October 2022

Abstract
Given a string T with length n whose characters are drawn from an ordered alphabet of size σ, its longest Lyndon subsequence is a longest subsequence of T that is a Lyndon word. We propose algorithms for finding such a subsequence in O(n 3) time with O(n) space, or online in O(n 3) space and time. Our first result can be extended to find the longest common Lyndon subsequence of two strings of length n in O(n 4 σ) time using O(n 2) space.
A Novel Analog Circuit Fault Diagnosis Method Based on Multi-channel 1D-Resnet and Wavelet Packet Transform
Authors: Zhou Xin , Tang Xuanzhong , Liang Wenhai 
Published: October 2022

Abstract

Fault diagnosis techniques for analog circuits are widely applied in the diagnosis of electronic devices. It is of great significance to accurately and quickly find the fault location and the deviation of fault parameters in analog circuits. In this paper, we propose an innovative fault diagnosis approach for analog circuits. In this method, the wavelet packet transform (WPT) is employed to preprocess the time-domain response signals of analog circuit, and the proposed multi-channel one-dimensional residual networks (MC-1D-ResNet) is utilized for feature mining and fault diagnosis. Specifically, the two-level WPT is first carried out on the measured time-domain response signal to generate one approximate signal and three detailed signals. Additionally, the MC-1D-ResNet is developed by introducing a multi-channel structure based on 1D-ResNet, which can excavate and fuse various features from response signals and realize fault diagnosis. Through the simulation of the Sallen-key bandpass filter circuit and Four-opamp biquad high-pass filter circuit, the diagnostic reliability of this method has been fully verified. The results show that this method is very valuable for diagnosing faults of analog circuits and performs well on both test circuits. Even in the complex Four-opamp biquad high-pass filter circuit, the diagnostic accuracy can be up to 99.74%.
InSpectra – A Platform for Identifying Emerging Chemical Threats
Authors: Feraud Mathieu , O'Brien Jake , Samanipour Saer , Dewapriya Pradeep , Herwerden Denice van , Kaserzon Sarit , Wood Ian , Thomas Kevin 
Published: October 2022

Abstract
Non-target analysis (NTA) employing high-resolution mass spectrometry (HRMS) coupled with liquid chromatography is increasingly being used to identify chemicals of biological relevance. HRMS datasets are large and complex making the identification of potentially relevant chemicals extremely challenging. As they are recorded in vendor-specific formats, interpreting them is often reliant on vendor-specific software that may not accommodate the advancements in data processing. Here we present InSpectra, a vendor independent automated platform for the systematic detection of newly identified emerging chemical threats. InSpectra is web-based, open-source/access and modular providing highly flexible and extensible NTA and suspect screening workflows. As a cloud-based platform, InSpectra exploits parallel computing and big data archiving capabilities with a focus for sharing and community curation of HRMS data. InSpectra offers a reproducible and transparent approach for the identification, tracking and prioritisation of emerging chemical threats.
Dominant changes in centre Fe atom of decamethyl-ferrocene from ferrocene in methylation
Authors: Wang Feng , Chantler Christopher T. 
Published: October 2022

Abstract
Staggered decamethyl-ferrocence (*Fc) becomes the lower energy conformer at low temperature, whereas the eclipsed conformer of ferrocence (Fc) is more stable. The powerful infrared (IR) spectroscopy which has remarkably provided signatures of ferrocene (Fc) in eclipsed and staggered conformers recently is employed to investigate methylation of Fc. The most significant consequences of the full methylation of Fc in the IR spectra are the blue shift of the band at ~800 cm-1 in Fc to ~1500 cm-1 in *Fc, and the band enhancement of the C-H stretch band ~3200 cm-1 region in *Fc. Further analysis reveals large impact of Fc methylation on core electron energies of the centre Fe atom (1s 2 2s 2 2p 6 3s 2 3p 6). Such the Fe core electron energy changes can be as large as ~10 kcal⋅mol −1 and are directional – the Fe 2pz and 3pz orbitals along the *Cp-Fe-*Cp axis (vertical) change more strongly than other Fe core electrons in px and py orbitals. Such the directional inner shell energy changes are evidenced by larger inner shell reorganization energy. Energy decomposition analysis (EDA) indicates that methyl groups in *Fc apparently change the physical energy components with respect to Fc. The large steric energy of *Fc is evidence that the closest hydrogens on adjacent methyl groups of the same *Cp ring in crystal structure are 0.2-0.4 Å closer than the hydrogens on nearest-neighbour methyl groups on opposing rings in *Fc. A significant increase in Pauli repulsive energy contributes to the large repulsive steric energy in *Fc. *This article is in honour of Professor Pratim Kumar Chattaraj on the occasion of his 65th birthday, for his contributions to Theoretical and Computational Chemistry.
Factors Influencing Sexual and Reproductive Health-related Misuse of Digital Media in Bangladesh
Authors: BakiBillah Abul Hasan , Chowdhury ABM Alauddin 
Published: October 2022

Abstract
This study explored factors influencing the sexual and reproductive health-related misuse of digital media in Bangladesh. The study adopted Key-Informant-Interview (KII) among the Nineteen (19) relevant key informants including academicians, researchers, policymakers, and activists. The thematic analysis of the transcripts was carried out. The mean age of the informants was 40 (SD+/- 6.8) years with having a minimum level of a bachelor degree. Easy access to indecent (porn) sites, low self-awareness of the girls in using social networking sites and other digital devices, the culture of injustice and muscle-men phenomenon, parent’s negligence, and the level of awareness were found as the major factors behind the misuse of digital media in the form of cyber-bullying, sexting, revenge porn, sextortion, access to and production of porn videos, etc. This study revealed that women and girls are the prime victims of the misuse where the worst form of victimization is to lead a deplorable life as a sex-slave and persist with chronic mental disorders. The study recommended that the complete ban on provocative indecent websites, high level of awareness among the women and girls, seeking immediate help from the law-enforcement agencies, and importantly, parents’ full-fledged care and attention.
Prevalence and Factors Associated with Genital Tobacco Powder Use Among Women in Gambia: A Mixed Study
Authors: Jaiteh Musa , Awolude Olutosin A. , Tunkara-Bah Haddy 
Published: October 2022

Abstract
Background
Genital tobacco powder, locally known as "tabaa," is a mixture of powdered tobacco and other substances that women use vaginally for sexual enhancement. Through a media report, the Ministry of Health issued a warning for women to stop the practice. However, literature search showed that no any scientific study documenting the burden of this cultural practice beyond media reports. The aim of this study was to determine the prevalence and factors associated with genital tobacco powder use among women in The Gambia.
Methods
A sequential exploratory mixed approach was used. The research was carried out in two areas of The Gambia: one rural (Farafenni) and one urban (Banjul). Focus group discussions and in-depth interviews were used to recruit (30) participants in the qualitative study. The quantitative study interviewed (400) women using structured questionnaire that was developed from the qualitative results. SPSS version 24 and STATA version 7 were used to analyze the data. Descriptive, Bivariate and multivariate statistics were used to summarize the data.
Results
Most of the study participants were between 30–39 years old who were married. The prevalence (17.0%; n = 68) of genital tobacco powder was high among women aged 40 years and above (OR = 2.88; 95% CI = 1.03–8.05; p = 0.04), from Farafenni and satellite villages (OR = 2.01; 95% CI = 1.02–3.96; p = 0.04), had non-formal education (OR = 3.09; 95% CI 0.85–11.26; p = 0.02) and had husbands who traveled for 6 (OR = 6.67; 95% CI = 1.71–26.01; p = 0.006) or 12 or more months (OR = 9.64; 95% CI 3.19–29.18; p < 0.001). The perception of women and peer influence were associated with genital tobacco powder use.
Conclusion
Genital tobacco powder is practiced all over the Gambia and highest in the rural areas. Socio-demographic variables such age, residence, marital status, education status were significantly associated with the practice. According to the findings, women with low level of education and have poor perception can easily be convinced by close friends/family members to use genital tobacco powder. Therefore, awareness creation is the most important intervention to mitigate this practice.