bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thiol‐Functionalized Metal‐Organic Frameworks Bonded to Cubic CdS: A New Synthesis of a Heterostructure with High Activity for Splitting Water into H2 under Visible‐Light Irradiation
Authors: Wang Yi‐Fan , Sun Jie , Han Yu‐Chen , Feng Li , Li Guo‐Qiang , Gao Hui , Gu Xiao‐Ling , Hu Si‐Yuan , Deng Yu‐Heng , Wan Chong‐Qing 
Published: February 2022

AbstractA large amount of CdS‐loaded composite UiO‐66‐(SH)2−CdS (104 wt %) was obtained by using a thiol‐functionalized UiO‐66‐(SH)2 through a well‐designed, two‐step, solid‐solution doping method. The thiol groups on the Metal‐Organic Framework couple with the cubic CdS nanoparticles to uniformly distribute over the UiO‐66‐(SH)2. A series of UiO‐66‐(SH)2−CdS‐x (0.4<x<3.5) with heterostructure were obtained and characterized via XPS, HRTEM, FTIR, XRD, BET and zeta potential measurements. The bonding/bridging anion −S− between the UiO‐66‐(SH)2 and the cubic CdS particles played a determinant role in the efficient charge transport, and acted as an analogous homojunction to significantly improve the photoactive properties. Pt/UiO‐66‐(SH)2−CdS‐2.5 showed a remarkable H2 evolution activity (37729 μmol g−1 h−1) from water (λ>400 nm), a high quantum efficiency, 25.8 %, at 420 nm and a perfect stability, which retained photocatalytic activity even after the catalyst had been soaked in boiling water for 24 h.
Passivating the pH‐Responsive Sites to Configure a Widely pH‐Stable Emulsifier for High‐Efficiency Benzyl Alcohol Oxidation
Authors: Shan Yuanyuan , Yu Chang , Zhang Mengdi , Wei Qianbing , An Jialong , Lv Huihui , Ni Lin , Qiu Jieshan 
Published: February 2022

AbstractWidely pH‐stable emulsions configured by solid emulsifiers with high chemical stabilities and anti‐corrosion properties under strong acid or alkaline conditions are highly sought after for practical and wide application of Pickering interfacial catalysis. Herein, a unique strategy was reported for synthesis of a widely pH‐stable and novel emulsifier by passivating the pH‐responsive sites on graphene oxide nanoribbon (GONR) surface using ionic liquid (IL). The suitable wettability of GONR‐IL was derived from the positive binding energy between IL and water, which ensured the stability of the emulsion in a wide pH range. Benefiting from the passivated surface chemistry of GONR, the emulsion microreactor stabilized by GONR‐IL exhibited a remarkable stability over a wide range of pH values. A GONR‐IL‐supported Pd catalyst stabilized at the toluene–water interface achieved an excellent emulsion catalytic activity for benzyl alcohol oxidation (conversion of 92 %), which was exceedingly higher than that of Pd/GONR (<1 %), Pd/CNTs‐IL (51 %), or Pd/GO‐IL (8 %).
A Convenient and Stable Heterogeneous Nickel Catalyst for Hydrodehalogenation of Aryl Halides Using Molecular Hydrogen
Authors: Leonard David K. , Ryabchuk Pavel , Anwar Muhammad , Dastgir Sarim , Junge Kathrin , Beller Matthias 
Published: February 2022

AbstractInvited for this month′s cover is the group of Matthias Beller at the Leibniz Institute for Catalysis in Rostock in collaboration with Muhammad Anwar and Sarim Dastgir at the Qatar Environment and Energy Research Institute in Doha. The image illustrates a hydrodehalogenation of polybrominated diphenyl ether (PBDE) using a heterogeneous nickel catalyst supported on titanium oxide and dihydrogen. The Research Article itself is available at 10.1002/cssc.202102315.
A novel hybrid meta‐heuristic concept for green communication in IoT networks: An intelligent clustering model
Authors: Akhtar MD Mobin , Ahamad Danish , Abdalrahman Alameen Eltoum M. , Shatat Abdallah Saleh Ali , Shatat Ahmad Saleh Ali 
Published: February 2022

SummaryNowadays, there is an emerging need for applications based on the Internet of Things (IoT). The sensor nodes present in the IoT network produce data constantly, which directly influences the durability of the network. Therefore, two major challenges while designing IoT systems are network lifetime and energy consumption. Although the ability of IoT applications is huge, there are several limitations such as energy optimization, heterogeneity of devices storage, load balancing, privacy, and security that have to be addressed. These constraints have to be optimized for improving the efficiency of the networks. Hence, the main intention of this paper is to develop the intelligent‐based cluster head selection model for accomplishing green communication in IoT. The two famous algorithms like spotted hyena optimization (SHO) and sun flower optimization (SFO) are integrated to form sun flower‐spotted hyena optimization (SF‐SHO) by utilizing the hybrid meta‐heuristic concept for the optimal cluster head selection. The most significant parameters in IoT networks like delay, distance, energy, temperature, and load are considered for deriving a multi‐objective function to offer optimal clustering. The cluster head of the model is optimally tuned based on the hybrid SF‐SHO, to solve the multi‐objective problem, thus showing the enhanced green communication performance. The proposed model is analyzed and evaluated over different approaches in terms of energy‐specific factors, and the attained results confirm the efficiency of the developed method.
Blood urea nitrogen to serum albumin ratio as a new prognostic indicator in critical patients with chronic heart failure
Authors: Lin Zebin , Zhao Yipin , Xiao Li , Qi Chenlu , Chen Qinwei , Li Yin 
Published: February 2022

AbstractAimsChronic heart failure (CHF) is often a common comorbidity in critically ill patients admitted to the intensive care unit (ICU) and carries an extremely poor prognosis. The study aimed to investigate the relationship between the blood urea nitrogen to serum albumin ratio (BAR) and the prognosis of patients with CHF admitted to the ICU.Methods and resultsThis retrospective cohort study included 1545 critically ill patients with CHF as a diagnosed comorbidity admitted to the ICU deposited in the MIMIC‐III database, of whom 90 day all‐cause mortality was 27.6% (n = 427) and in‐hospital mortality was 17.3% (n = 267). The results of multiple logistic regression analysis indicated that BAR is an independent risk factor for in‐hospital mortality in critically ill patients with CHF [compared with BAR ≤ 0.83; 0.83 < BAR ≤ 1.24: odds ratio (OR) 2.647, 95% confidence interval (CI) 1.797–3.900, P < 0.001; BAR ≥ 1.24: OR 3.628, 95% CI 2.604–5.057, P < 0.001]. Multiple COX regression analysis found a relationship between BAR and all‐cause mortality at 90 day follow‐up (0.83 < BAR ≤ 1.24: OR 1.948, 95% CI 1.259–3.014, P < 0.003; BAR ≥ 1.24: OR 1.807, 95% CI 1.154–2.830, P < 0.01; BAR ≤ 0.83 as a reference). Kaplan–Meier curves also showed similar results as well (P < 0.001). The areas under the receiver operating characteristic curves for predicting in‐hospital mortality and 90 day all‐cause mortality were 0.622 and 0.647, respectively.ConclusionsBAR is an independent risk factor for in‐hospital mortality and 90 day mortality in critically ill patients with CHF admitted to the ICU.
The value of echocardiographic measurement of epicardial adipose tissue in heart failure patients
Authors: van Woerden Gijs , van Veldhuisen Dirk J. , Gorter Thomas M. , Ophuis Bob , Saucedo‐Orozco Huitzilihuitl , van Empel Vanessa P.M. , Willems Tineke P. , Geelhoed Bastiaan , Rienstra Michiel , Westenbrink Berend Daan 
Published: February 2022

AbstractAimsEpicardial adipose tissue (EAT) is increasingly recognized as an important factor in the pathophysiology of heart failure (HF). Cardiac magnetic resonance (CMR) imaging is the gold‐standard imaging modality to evaluate EAT size, but in contrast to echocardiography, CMR is costly and not widely available. We investigated EAT thickness on echocardiography in relation to EAT volume on CMR, and we assessed the agreement between observers for measuring echocardiographic EAT.Methods and resultsPatients with HF and left ventricular ejection fraction >40% were enrolled. All patients underwent CMR imaging and transthoracic‐echocardiography. EAT volume was quantified on CMR short‐axis cine‐stacks. Echocardiographic EAT thickness was measured on parasternal long‐axis and short‐axis views. Linear regression analyses were used to assess the association between EAT volume on CMR and EAT thickness on echocardiography. Intraclass correlation coefficient (ICC) was used to assess the interobserver agreement as well as the intraobserver agreement. EAT on CMR and echocardiography was evaluated in 117 patients (mean age 71 ± 10 years, 49% women and mean left ventricular ejection fraction 54 ± 7%). Mean EAT volume on CMR was 202 ± 64 mL and ranged from 80 to 373 mL. Mean EAT thickness on echocardiography was 3.8 ± 1.5 mm and ranged from 1.7 to 10.2 mm. EAT volume on CMR and EAT thickness on echocardiography were significantly correlated (junior‐observer: r = 0.62, P < 0.001, senior‐observer: r = 0.33, P < 0.001), and up to one‐third of the variance in EAT volume was explained by EAT thickness (R2 = 0.38, P < 0.001). The interobserver agreement between junior and senior observers for measuring echocardiographic EAT was modest [ICC, 0.65 (95% confidence interval (CI) 0.47–0.77], whereas the intraobserver agreement was good (ICC 0.98, 95% CI 0.84–0.99).ConclusionsThere was a modest correlation between EAT volume on CMR and EAT thickness on echocardiography. Limited agreement between junior and senior observers for measuring echocardiographic EAT was observed. EAT thickness on echocardiography is limited in estimating EAT volume.
Severe Problems of the Voltage‐Clamp Method in Concurrent Monitoring of Membrane Potentials
Authors: Kaji Maiko , Yamada Yusuke , Kitazumi Yuki , Shirai Osamu 
Published: February 2022

AbstractIn nerve cells, the concurrent monitoring of multipoint on the axon has been conducted based on the voltage‐clamp method using two long parallel electrodes inside and outside the axon. As the respective membrane potentials have been evaluated by considering the clamping potential, the local current, and the conductance, the membrane potentials were not actually evaluated. We directly measured the actual membrane potentials and local currents of the respective cells using a nerve‐model‐system comprising some liquid‐membrane cells. It is proved that the action potential propagation is artificially facilitated or prevented by both the external electric generator and two long electrodes.
Tamjanika, a Balkan native variety of Vitis vinifera L.: Chemical characterization, antibacterial, and anti‐dermatomycosis potential of seed oil
Authors: Đorđevski Nikoleta , Stojković Dejan , Živković Jelena , Pljevljakušić Dejan , Ristanović Elizabeta , Nikolić Biljana , Ćirić Ana 
Published: February 2022

AbstractThis study was designed to explore functional food properties of edible seed oil obtained from Tamjanika seeds—autochthonous grape variety of Balkan Peninsula. In order to accomplish our goals, seed oil was isolated by Soxhlet apparatus and chemically characterized regarding fatty acids, carotenoids, tocopherols, and tocotrienols. Antimicrobial activity of the isolated oil was tested by microdilution method. For that purposes, six bacterial species were used, belonging to human infectious agents and food contaminants. Furthermore, the activity of the oil was investigated against clinical isolates of dermatomycetes. Our study has shown that oil of Vitis vinifera L. Tamjanika variety was an abundant source of polyunsaturated fatty acids (81.43%) with predominant linoleic acid. HPLC analysis revealed the presence of carotenoid lutein (0.15 mg/100 g). The seed oil was rich in tocotrienols (85.04 mg/100 g) predominating over tocopherols (8.37 mg/100 g). The oil possessed microbicidal activity against all the tested microbes. Bacteria were more sensitive to the effect of the oil (minimum inhibitory concentration [MIC] 7.7–15.4) when compared with oil effect on tested dermatomycetes (MIC 20–40). Our investigation has shown for the first time that grape oil could be active against wide spectrum of bacteria and clinically isolated dermatomycetes. The significance of this study lies in the fact that it pointed out the functional food properties of grape seed oil that was fully chemically characterized.
A Genetic and Metabolic Staging System for Predicting the Outcome of Nonalcoholic Fatty Liver Disease
Authors: Pennisi Grazia , Pipitone Rosaria Maria , Enea Marco , De Vincentis Antonio , Battaglia Salvatore , Di Marco Vito , Di Martino Vincenzo , Spatola Federica , Tavaglione Federica , Vespasiani‐Gentilucci Umberto , Zito Rossella , Romeo Stefano , Cammà Calogero , Craxì Antonio , Grimaudo Stefania , Petta Salvatore 
Published: February 2022

Nonalcoholic fatty liver disease (NAFLD) is an emerging cause of liver‐related events (LREs). Here, we have assessed the ability of a composite score based on clinical features, metabolic comorbidities, and genetic variants to predict LREs. A total of 546 consecutive patients with NAFLD were recruited and stratified according to the fibrosis‐4 (FIB‐4) index. LREs were defined as occurrence of hepatocellular carcinoma or hepatic decompensation. Cox regression multivariate analysis was used to identify baseline variables associated with LREs. The UK Biobank was used as the validation cohort, and severe liver disease (incidence of cirrhosis, decompensated liver disease, hepatocellular carcinoma, and/or liver transplantation) was used as the outcome. LREs were experienced by 58 patients, only one of whom was in the cohort of patients with a FIB‐4 score < 1.3. Multivariate Cox regression analysis of 229 patients with a FIB‐4 score ≥ 1.3 highlighted clinical variables independently associated with the development of LREs, including older age, low platelet count, low albumin, low high‐density lipoprotein cholesterol, certain genetic factors, and interactions between genetic factors and sex or diabetes. The area under the curve (AUC) for the model was 0.87 at 1, 3, and 5 years. Our novel Genetic and Metabolic Staging (GEMS) scoring system was derived from the Cox model linear predictor, ranked from 0 to 10, and categorized into five classes (0‐5, 5‐6, 6‐7, 7‐8, and 8‐10). The risk of LREs increased from 4% in patients in the best class (GEMS score 0‐5) to 91% in the worst (GEMS score 8‐10). GEMS score was associated with incident severe liver disease in the study population (hazard ratio, 1.56; 95% confidence interval, 1.48‐1.65; P < 0.001) as well as in the UK Biobank cohort where AUCs for prediction of severe liver disease at 1, 3, and 5 years were 0.70, 0.69, and 0.67, respectively. Conclusion: The novel GEMS scoring system has an adequate ability to predict the outcome of patients with NAFLD.
Policy and praxis in data democratization efforts: A case study of Minnesota State's Equity 2030
Authors: Hinds Teri Lyn , Floyd Nancy D. , Ueland Jeffrey S. 
Published: February 2022

AbstractIn June 2019, Minnesota State set a critical goal: By 2030, eliminate the educational equity gaps at each of the 30 colleges and 7 universities that comprise the system. To achieve the goal of Equity 2030, and empower actors at every level of Minnesota State, system and campus leaders need to fully embrace data democratization. Without access to data that can guide discovery of equity gaps within the context of their own work, faculty and staff lack critical information. When educators use data to guide inquiry and action, they can check any assumptions or biases they may have as well as understand if a change they are making is effective in closing the gap or addressing the need. Data security and ethical and responsible use must be emphasized, but data democratization calls for intentional examination of institutional policies to ensure people have the information they need to identify, implement, and evaluate changes in their approaches to create more equitable outcomes. To advance the work of Equity 2030, Minnesota State is working to review policies and practices around data sharing, specifically with faculty and staff, as well as working to create resources and training to support ethical and appropriate use of data to support student success. This article will establish the current state of efforts at the system office level, including an upcoming multi‐year transition to a new system‐wide enterprise resource planning platform and complications arising from the centralized collection and maintenance of institution‐level data within the system office, as well as outline the strategic and tactical approach to democratizing data while maintaining security and confidentiality.
Engineering a highly elastic bioadhesive for sealing soft and dynamic tissues
Authors: Ghovvati Mahsa , Baghdasarian Sevana , Baidya Avijit , Dhal Jharana , Annabi Nasim 
Published: February 2022

AbstractInjured tissues often require immediate closure to restore the normal functionality of the organ. In most cases, injuries are associated with trauma or various physical surgeries where different adhesive hydrogel materials are applied to close the wounds. However, these materials are typically toxic, have low elasticity, and lack strong adhesion especially to the wet tissues. In this study, a stretchable composite hydrogel consisting of gelatin methacrylol catechol (GelMAC) with ferric ions, and poly(ethylene glycol) diacrylate (PEGDA) was developed. The engineered material could adhere to the wet tissue surfaces through the chemical conjugation of catechol and methacrylate groups to the gelatin backbone. Moreover, the incorporation of PEGDA enhanced the elasticity of the bioadhesives. Our results showed that the physical properties and adhesion of the hydrogels could be tuned by changing the ratio of GelMAC/PEGDA. In addition, the in vitro toxicity tests confirmed the biocompatibility of the engineered bioadhesives. Finally, using an ex vivo lung incision model, we showed the potential application of the developed bioadhesives for sealing elastic tissues.
The Effect of Fracture Recency on Observed 10-Year Fracture Probability: A Registry-Based Cohort Study
Authors: Leslie William D , Morin Suzanne N , Lix Lisa M , McCloskey Eugene V , Johansson Helena , Harvey Nicholas C , Kanis John A 
Published: February 2022

ABSTRACT
FRAX estimates 10-year fracture major osteoporotic fracture (MOF) and hip fracture probability from multiple risk factors. FRAX does not consider prior fracture site or time since fracture. Fracture risk is greater in the initial 2-year post-fracture period (imminent risk), implying that FRAX may underestimate risk in this setting. We used the population-based Manitoba Bone Mineral Density (BMD) Program registry to examine the effect of fracture recency and site on incident fracture risk predictions using FRAX. We identified women aged 40 years or older with baseline BMD and FRAX scores. Observed fracture outcomes to 10 years were compared with predicted 10-year fracture probability stratified by prior fracture status: none, recent (&lt;2 years [median 0.3 years]), and remote (≥2 years [median 10.6 years]). For women with recent fractures, we also examined proposed multipliers to adjust FRAX for the effect of fracture recency and site. The cohort comprised 33,465 women aged 40 to 64 years (1897 recent fracture, 2120 remote fracture) and 33,806 women aged ≥65 years (2365 fracture, 4135 remote fracture). Observed fracture probability was consistent with predicted probability in most analyses. In women aged 40 to 64 years, there was a significant effect of recent vertebral and humerus fracture on MOF (observed to predicted 1.61 and 1.48, respectively), but these effects were still lower than the proposed multipliers (2.32 and 1.67, respectively). No significant effect of fracture recency was found after hip or forearm fracture in either age group. Our findings contribute to accumulating evidence of the importance of recent fracture. The effect of fracture recency was not consistent across fracture sites and with a lower magnitude than previously reported. Further quantification of effect size and specificity in additional independent cohorts is warranted to validate and refine recent-fracture multipliers in fracture risk assessment. © 2022 American Society for Bone and Mineral Research (ASBMR).
The influence of tetrel bonds on the acidities of group 14 tetrafluoride ‐ inorganic acid complexes
Authors: Brzeski Jakub 
Published: February 2022

AbstractAb initio methods were used to determine the influence of tetrel bond formation on the acidity. The systems composed of inorganic acids and tetrafluorides of 14 group elements have been tested ‐ HA/EF4, where HA = H2O, NH3, HF, HCN, HNC, HCNO, HOCN and E = C, Si, Ge, Sn or Pb. It turns out that the electron density flow involved with formation of tetrel bond to carbon‐based systems leads to negligible increase in acidity. In the case of the acceptor compounds based on the remaining 14 group elements however, the effect is much more apparent, as most of those compounds may be considered a Brønsted superacids. The electronic stability of anions formed after the deprotonation of aforementioned complexes has been investigated. Vast majority of the anions were found to exhibit significant electron binding energies.
Serum amyloid a, C‐reactive protein, and procalcitonin levels in children with Mycoplasma pneumoniae infection
Authors: Jiang Yuanyuan , Wang Wenyang , Zhang Zhijun , Ma Xianfen , Sang Yanyan , Wang Jin , Xu Guoxiang , Feng Qiang , Zhao Shuping 
Published: February 2022

AbstractBackgroundMycoplasma pneumoniae (MP) is a common pathogen of community‐acquired pneumonia in children. In the present study, serum amyloid A (SAA), C‐reactive protein (CRP), and procalcitonin (PCT) levels in children with MP infection were analyzed and the differential diagnoses of MP evaluated.MethodsThe study included 152 children with MP infection hospitalized in Tai’an Central Hospital in Shandong Province and 50 healthy children as controls. SAA, CRP, and PCT, as well as serum immunoglobulins and T lymphocyte subsets were analyzed during the acute and convalescent phases. Among the MP‐infected children, 30 cases were selected to monitor the SAA, immunoglobulins, and T lymphocyte subset levels for a week.ResultsThe SAA, CRP, PCT, IgA, and IgM levels were significantly higher in the MP‐infected group than in the control group (F(SAA) = 83.91, p < 0.05; F(CRP) = 40.79, p < 0.05; F(PCT) = 60.58, p < 0.05; F(IgA) = 43.45, p < 0.05; F(IgM) = 233.88, p < 0.05). In addition, the levels of these factors were significantly higher in the acute phase than in the convalescent phase (p < 0.05). However, significant difference was not observed in the IgG level between these two groups (p > 0.05). The CD3+ and CD4+ levels in the MP‐infected group were lower than in the control group ( F(CD3+)= 60.58, P < 0.05; F(CD4+) = 89.05, p < 0.05), and the CD8+ level was higher than in the control group ( F(CD8+)= 96.96, p < 0.05). The CD3+, CD4+, and CD8+ levels were significantly different between the acute phase and the convalescent phase (CD3+: acute phase vs. convalescent phase, q = 2.79, p < 0.05; CD4+: acute phase vs. convalescent phase, q = 2.83, p < 0.05; CD8+: acute phase vs. convalescent phase, q = 3.15, p < 0.05). The changes in serum SAA levels in the MP‐infected group positively correlated with the changes in IgA, IgM, and CD8+ levels and negatively correlated with CD3+, CD4+, and CD4+/CD8+.ConclusionSAA, CRP, and PCT were specific markers for diagnosing early MP infection in children. These findings are important in the differential diagnosis of MP infection and clinical guidance for MP treatment.