bluuebunny/crossref_metadata_2025_split huggingface dataset:
Transitioning of people with T1D from Multiple Daily Injections (MDI) and Self-Monitoring of Blood Glucose (BGM) directly to MiniMed™ 780G Advanced Hybrid Closed Loop (AHCL) system: a two-center, randomized controlled study
Authors: Matejko Bartłomiej , Juza Anna , Kieć-Wilk Beata , Cyranka Katarzyna , Krzyżowska Sabina , Chen Xiaoxiao , Cohen Ohad , Silva Julien Da , Malecki Maciej T , Klupa Tomasz 
Published: August 2022

<p> </p>
<p>Objective: The aim of this study was to evaluate the outcomes of transitioning to the MiniMed™ 780G advanced hybrid closed-loop (AHCL) system in adult individuals with type 1 diabetes (T1DM) naïve to CSII and CGM technologies. </p>
<p>Research Design and Methods: The trial was a two-center, randomized controlled, parallel group study evaluating individuals with T1DM aged 26-60 years managed with Multiple Daily Injection (MDI) and self-monitoring of blood glucose (BGM), with an HbA1c <10%. </p>
<p>Results: 41 participants were recruited and randomized to either the AHCL (20) or the MDI+BGM (21) group. 37 participants (age 40.3±8.0 years; duration of diabetes 17.3 ± 12.1 years; BMI 25.1±3.1 kg/m2; HbA1c 7.2% ± 1.0) completed the study. Time spent in target (TIR) increased from 69.3±12.3% at baseline to 85.0±6.3% at 3 months in the AHCL group, while remaining unchanged in the control group: treatment effect 21.5% [95% CI 15.7, 27.3%]; p < 0.001. The Time Below Range (<70 mg/dl; TBR) decreased from 8.7%±7.3 to 2.1%±1.7 in the AHCL group and remained unchanged in the MDI+BGM group (treatment effect -4.4% [95% CI -7.4, -2.1%]; P < 0.001). Participants from the AHCL group also had significant improvements in HbA1c levels (treatment effect -0.6% [95% CI -0.9, -0.2]; p=0.005) and in the quality of life in specific subscales, compared to the MDI+BGM group.</p>
<p>Conclusions: People with T1DM naïve to CSII and CGM technologies initiating AHCL significantly and safely improved their glycemic control, as well as their quality of life and psychological well-being.</p>
HPHC Testing of Tobacco and Smoke to Examine Cigarette Temporal Variability
Authors: Tayyarah Rana , Morton Michael J. , Flora Jason W. 
Published: August 2022

Summary
Commercial cigarettes were analyzed for harmful and potentially harmful constituents (HPHCs) in tobacco and smoke to investigate temporal product variability independent of analytical variability over one week, one year, and three years. Cigarettes from the worldwide market with various design features were collected over a 3-year period, stored, and tested concurrently for HPHCs to minimize analytical variability; repeat testing of reference cigarette 3R4F was included as an analytical control for the study design. Physical parameters were found to be relatively consistent. No trends in variability were noted based on blend type, smoke analyte matrix, or magnitude of an HPHC's yield. Combustion-related HPHCs generally showed low variation. Long-term batch-to-batch variability was found to be higher than short-term variability for tobacco-related compounds that have the potential to vary over time due to weather and agronomic practices. “Tar”, nicotine, and carbon monoxide were tested in multiple labs and showed greater lab-to-lab variability than batch-to-batch variability across all phases. Based on the results of this study, commercial cigarette products appear to have relatively low product variability. The low analyte variability noted in this study with products tested under unconventionally controlled analytical conditions serves to indicate that analytical variability may be a significant contributor to overall variability for general product testing over time and in interlaboratory studies. Laboratory controls and using a matched reference product across studies and between laboratories are important to assess testing differences and variability.
Origin and genetic nature of polyploidy in paleoendemic coast redwood (Sequoia sempervirens(D. Don) Endl.)
Authors: Ahuja M. Raj 
Published: August 2022

AbstractIt is not known when the polyploid coast redwood (Sequoia sempervirens) evolved from its diploid ancestors, and what is its type of polyploidy. Whether close relatives ofSequoia, giant sequoia (Sequoiadendron giganteum) and dawn redwood (Metasequoia glyptostroboides), have possibly contributed to the ancestry of hexaploid ofSequoiaremains an open question. The nature of hexaploidy inSequoiahas baffled biologists for more than a century. Based on the chromosome configurations inSequoia, G. Ledyard Stebbins was the first geneticists who postulated in 1948 thatSequoiais an autoallohexaploid (AAAABB), and an ancient species ofMetasequoiamight have been one of the putative ancestors ofSequoia. After its chromosome number (2n=6x=66) was confirmed in hexaploidSequoia, the type of polyploidy inSequoiahas been further investigated for the past 70 years by a number of investigators, using cytogenetic and genetic data. Although an autoallohexaploid (AAAABB) origin ofSequoiahas remained one of the dominant hypotheses until recently, an alternative hypothesis, amongst other possible origins, was also put forth by Ahuja and Neale (2002), thatSequoiamay be partially diploidized autohexaploid (AAAAAA), derived from some ancestral species ofSequoia, thus carrying a single ancestral genome. Cytogenetic, molecular genetics, and genome sequence data now support the hypothesis thatSequoiaoriginated as an autohexaploid.
International and National Regulations on Management of Pharmaceutical Products and their Post-Consumer Waste
Authors: Paula Araújo Anne Carolina de , Farias Nobrega Thiago , Souza do Amaral Viviane 
Published: August 2022

Purpose: To analyze the international and national legal and normative devices regarding the management of pharmaceutical products and their post-consumption waste. To guide this review, the following question was posed: what is the national and international evidence on the management of pharmaceutical products and their post-consumption waste?

Method/design/approach: Descriptive review consisting of an investigation of technical and normative documents. To this end, representative countries of the European Union, North America, and South America were included in this review.

Results and conclusion: They were found to be: (1) the European Union model, which is characterized in a general framework for all Member States; (2) the North American model, where most countries are not subject to a common regulatory framework; (3) the South American model, where most countries have legal provisions implemented at the national level. Thus, it is inferred that the countries analyzed have regulations, even if in different spheres of government.

Research implications: The contributions point to the knowledge of the legislations, provoking questioning about the way they are being executed and the concretization of these changes.

Originality/value: The development of this research allows us to know the history of the legislations and have a broader and more critical view of the theme, so that measures can be taken to mitigate and remediate the impacts.
Qualidade de vida de servidores públicos em um município no Vale do Jequitinhonha, Minas Gerais
Authors: Silva Clayton Samuel , Campos Luciana Freitas , Morais Harriman Aley 
Published: August 2022

O termo “qualidade de vida”, embora amplamente presente na literatura, ainda é pouco discutido quando se trata de servidores públicos municipais. Assim, o objetivo desta pesquisa foi o de avaliar a percepção da qualidade de vida de profissionais vinculados a uma prefeitura de um município de pequeno porte, localizado no Vale do Jequitinhonha, em Minas Gerais. Para tanto, aplicou-se o questionário WHOQOL-Bref a 85 trabalhadores do serviço público, sendo os dados coletados analisados por meio do cálculo de escores, conforme preconizado pela Organização Mundial de Saúde. Verificou-se que a média da qualidade de vida foi de 65,5 sendo o maior escore observado no domínio social (70,1) e o menor no domínio ambiente (57,8), sendo que algumas facetas, como a insatisfação salarial e aspectos associados ao estresse avaliados como críticos. Concluiu-se, portanto, que a qualidade de vida foi considerada boa pela maioria dos entrevistados, porém novos estudos são necessários para melhor compreender as facetas críticas do estudo e, assim, propor um plano de ações para a gestão pública municipal.
Intergenerational Income Mobility in New Zealand
Authors: Brown Simon 
Published: August 2022

Intergenerational mobility considers how a child’s outcomes are associated with their parents’ situation. If intergenerational mobility is low, then a child has less of a chance of moving up the income distribution relative to their parents. This can influence skills development, productivity growth and the achievement of improved living standards.
The findings presented in this article highlight the importance of policies that focus resources on improving educational outcomes for students from low socio-economic backgrounds, which would help lift intergenerational economic mobility and support higher living standards for all.
Technology Integrated Formative Assessment: Effects on Students’ Conceptual Knowledge and Motivation in Chemical Equilibrium
Authors: Hagos Tadesse , Andargie Dereje 
Published: August 2022

The main objective of this study was to evaluate the impact of technology integrated formative assessment strategies on students’ conceptual knowledge and their motivation in chemical equilibrium. Quasi-experimental control group interrupted time series design was employed. Data were collected from 132 students which were selected using multistage random sampling technique from three governmental secondary schools. Two experimental (Technology Integrated Formative Assessment (TIFA) and Formative Assessment (FA) alone) and one comparison groups were involved in the study. A series of chemical equilibrium conceptual tests and motivation questionnaire were used to collect data. One-way ANOVA and Mixed model ANOVA were used to analyze the test scores. There was a statistically significant difference between groups in posttest on conceptual plus remembering (F (2,129) = 3.52, p=.033), understanding (F (2,129) = 4.70, p=.033), applying (F (2, 129) = 20.35, p<.001) and their motivation (F (2, 129) = 12.375, p< .001). However, there were no statistically significant differences among groups in posttest on conceptual plus analysis (F (2, 129) = 1.10, p = .335) and evaluating (F (2,129) = 3.03, p = .052). There was also an interaction effect between treatment and time point on the conceptual test scores. It was concluded that TIFA more effective in facilitating students’ conceptual knowledge and motivation in learning chemical equilibrium than the two other groups. The researchers recommended that chemistry teachers should adapt TIFA as a teaching strategy in chemistry classrooms and laboratories. They are also recommended that teachers should incorporate it into their classes to enhance students’ motivation.

Key Words: Conceptual knowledge, Formative assessment, Motivation, Technology
Analisa Komparatif Cost of Rework dan Cost of Conformance to Quality sebagai dasar perbaikan sistem Proses Produksi (Studi Kasus di Industri Garmen HSN)
Authors: Sullyartha Esa Rengganis 
Published: August 2022

CV. HSN adalah perusahaan Garmen yang berlokasi di Kabupaten Karanganyar, Provinsi Jawa Tengah. Pada beberapa bulan terakhir ini, terjadi retur produk dikarenakan produk tersebut cacat, terutama Atasan Wanita Lengan Panjang. Jumlah produk yang diretur relatif banyak dan dibarengi dengan permintaan dari para customer yang meminta penggantian produk yang diretur tersebut. Dengan adanya kejadian ini perusahaan mengalami kerugian sehingga timbul keinginan untuk memperbaiki sistem produksi yang ada.Aktivitas pengendalian kualitas produk membutuhkan biaya pengendalian kualitas.. Jika terdapat produk cacat dan produk tersebut diperbaiki maka akan timbul yang namanya biaya rework. Biaya ini termasuk hidden cost yang tidak disadari oleh perusahaan. Selain biaya rework terdapat biaya pencegahan kualitas, yaitu biaya yang dikeluarkan oleh perusahaan untuk melakukan aktivitas pencegahab timbulnya produk cacat.Berdasarkan hasil penelitian didapatkan besarnya biaya rework yang harus dikeluarkan oleh perusahaan sebesar Rp. 176.195.000. Sedangkan biaya pencegahan kualitas yang harus dikeluarkan adalah sebesar Rp. 64.730.500. Dan jika perusahaan memilih mengeluarkan biaya pencegahan kualitas untuk memperbaiki sistem produksi maka estimasi keuntungan yang didapat sebesar Rp. 825.588.000..
Analisis Pengukuran Produktivitas Menggunakan Metode American Productivity Center (APC) dan Marvin E. Mundel sebagai Upaya Peningkatan Kinerja
Authors: Suseno Suseno , Fitri Rizky 
Published: August 2022

PT. Adi Satria Abadi merupakan perusahaan yang bergerak di bidang Leather and Leathergoods Manufacturing yang memproduksi penyamakan kulit. PT. Adi Satria Abadi beralamat di Banyakan, Kelurahan Sitimulyo, Kecamatan Piyungan, Kabupaten Bantul, Daerah Istimewa Yogyakarta. Permasalahan yang terjadi pada PT Adi Satria Abadi yaitu permasalahan yang dihadapi PT Adi Satria Abadi adalah belum mencapai target produksi sebesar 40.000 pcs/bulan yang telah ditetapkan. Dalam beberapa bulan yaitu pada bulan Juli, Agustus, September, November, dan Desember dengan jumlah produksi pada bulan Juli 36.201 pcs/bulan, Tujuan dari penelitian ini Untuk mengetahui pengukuran produktivitas dengan menggunakan metode American Productivity Center (APC) dan untuk mengetahui faktor penyebab turunnya produktivitas, untuk mengetahui pengukuran produktivitas dengan menggunakan metode Marvin E Mundel, Mengetahui metode mana yang lebih efisien digunakan untuk peningkatan produktitas kinerja. Berdasarkan perhitungan angka indeks produktivitas perusahaan diketahui bahwa terjadi fluktuasi produktivitas di setiap periodenya. Hal ini dapat diketahui dengan adanya penurunan dan kenaikan produktivitas, indeks tertinggi pada tenaga kerja adalah pada bulan Oktober 2021 yaitu sebesar 105%, indeks bahan baku yang tertinggi yaitu pada bulan Agustus 2021 sebesar 102%, indeks energi tertinggi yaitu pada bulan November 2021 sebesar 121%, indeks modal tertinggi yaitu pada bulan Oktober 2021 sebesar 107%, dan indeks tertinggi produktivitas total yaitu pada bulan Oktober 2021 sebesar 102%.
Pendidikan Karakter Berbasis Keluarga Terintegrasi Pembelajaran untuk Menanamkan Nilai-nilai Toleransi Sejak Dini
Authors: Aryani Nini , Wilyanita Nopa 
Published: August 2022

Keluarga merupakan kunci utama dalam pendidikan karakter, keluarga juga dapat dijadikan sebagai wadah belajar dalam hal mengajarkan nilai toleransi yang merupakan bagian dari kegiatan belajar TK mereka sejak dini . Oleh karenanya perlu adanya model pembelajaran karakter berbasis keluarga yang terintegrasi dengan pembelajaran di sekolah sebagai upaya dalam menanamkan nilai-nilai toleransi pada anak Penelitian ini bertujuan untuk memberikan rekomendasi model pembentukan karakter berbasis keluarga untuk mengajarkan nilai toleransi pada anak. Metode yang digunakan dalam penelitian ini adalah deskriptif analisis dengan menggunakan pendekatan kualitatif dan sumber data kepustakaan. Bagaimanapun juga, penelitian ini akan menjadi pedoman atau acuan bagi guru dalam melaksanakan pembentukan karakter untuk mengajar pada tingkatan yang dapat diterima sejak usia dini. Langkah penelitian yang dilakukan dengan cara melakukan wawancara kepada guru dan orang tua untuk mendapatkan informasi yang dibutuhkan. Hasil penelitian ini berupa model pendidikan karakter berbasis keluarga yang terintegrasi dalam pembelajaran dilihat dari tujuan pendidikan karakter, program, proses dan evaluasi yang disiapkan oleh guru namun penerapanya dalam keluarga.
Blended Learning untuk Pendidikan Anak Usia Dini: Implementasi dan Tantangannya
Authors: Mayar Farida , Desmila Desmila , Nurhamidah Nurhamidah , Rahmawati Rika , Uzlah Umi 
Published: August 2022

Pandemi Covid-19 menyebabkan sekolah perlu memilih metode pembelajaran yang sesuai. Salah satu metode yang dapat memfasilitasi siswa adalah blended learning. Penggunaan metode tersebut di satuan PAUD masih sangat minim pembahasannya. Artikel ini bertujuan untuk memberikan gambaran implementasi dan tantangan metode blended learning untuk anak usia dini menggunakan metode kualitatif fenomenologis. Enam guru PAUD di Yogyakarta menjadi partisipan yang dipilih melalui teknik purposive sampling. Teknik pengumpulan data yang digunakan menggunakan wawancara. Hasil dari analisis data menunjukkan bahwa terdapat lima tema yang menjadi fokus utama dalam implementasi metode blended learning. Aspek keterlibatan tersebut adalah : pemahaman guru terhadap metode blended learning, persiapan blended learning, respon dan pemahaman anak ketika blended learning, faktor yang mempengaruhi keberhasilan blended learning, kesesuaian metode blended learning untuk PAUD. Implikasi hasil penelitian dibahas lebih lanjut dalam artikel
Learning Space Management Nurul Islam Nature School (SANI) Jember to Cultivate Children's Spirituality
Authors: Istifadah Istifadah 
Published: August 2022

Learning space is a fundamental need in education. The availability of space for educational institutions is a necessity to accommodate all learning activities. This is no exception for early childhood education. The purpose of this study was to describe and analyze the management of the learning space to foster the value of children's spirituality. The research was conducted at the Nurul Islam Islamic School (SANI) at the Nurul Islam Islamic Boarding School Jember. The study focused on the analysis of the learning space for early childhood based on the theory of (Taylor et al., 2009), as well as several other relevant theories. Data was extracted through observation, interviews, documentation and photography and analyzed in three steps: data condensation, data presentation, and drawing conclusions or verification based on source triangulation. In this study, it was found that the management of the SANI learning space is a development of Taylor theory, namely the content, context, learning process, and spiritual values of the pesantren tradition in managing the SANI learning space
Pedoman Literasi Digital Guru untuk Meningkatkan Kemampuan Kognitif Anak Usia Dini
Authors: Anggita Indah Sri , Yusuf Hibana , Naimah Naimah , Putro Khamim Zarkasih 
Published: August 2022

Salah satu implikasi dari lemahnya literasi digital guru yaitu menurunya standar pencapaian kompentsi anak pada sektor kemampuan kognitif. Tujuan dalam penelitian ini adalah: meneliti literasi digital guru untuk meningkatkan kemampuan kognitif anak di RA. Metode Penelitian yang digunakan menggunakna pendekatan kualitatif deskriptif. Informan dalam penelitian ini adalah satu orang kepala sekolah, tiga orang guru kelas Tk A dan B, dengan 23 peserta didik. Teknik analisis data berupa induktif, meliputi tiga tahap yaitu redukasi data, penyajian data, serta penarikan kesimpulan, adapun teknik validity menggunakan triangulasi. Hasil penelitian ini menunjukkan bahwa implementasi literasi digital guru untuk meningkatkan kemampuan kognitif anak. Literasi digital guru dilakukan untuk meningkatkan standar pencapaian anak sesuai dengan kemendikbud 137. Ketiga implikasi literasi digital guru di RA adalah yaitu guru mampu meningkatkan mutu pendidikan pada saat pembelajaran daring.
Mengoptimalkan Dukungan Ibu dalam Meningkatkan Minat Baca Anak di Situasi Pandemi
Authors: Nasrida Vita , Royanto Lucia R.M. 
Published: August 2022

Tujuan penelitian adalah untuk mengetahui efektivitas program pembelajaran membaca permulaan dengan metode Sight Words dalam meningkatkan lingkungan keluarga yang mendukung literasi membaca dan meningkatkan minat baca anak. Penelitian ini menggunakan pendekatan kuantitatif kuasi eksperimental dengan desain penelitian one group pre-test post-test. Sampel dalam penelitian berjumlah 30 orang Ibu dengan anak usia 4-6 tahun yang diambil dengan teknik purposive sampling. Teknik pengumpulan data menggunakan kuesioner. Teknik analisis data menggunakan uji t-test. Hasil analisis data menunjukkan bahwa terdapat perbedaan minat baca anak sebelum dan sesudah diberikan kegiatan belajar membaca dengan pendampingan lewat metode Sight Words namun tidak terdapat perubahan yang signifikan terhadap HLE setelah dilakukan intervensi.
The Nation’s First Publicly-Recognized Overdose Prevention Centers: Lessons Learned in New York City
Authors: Giglio Rebecca , Mantha Shivani , Harocopos Alex , Saha Nilova , Reilly Jacqueline , Cipriano Chelsea , Kennelly Maura , Landau Lisa , McRae Michael , Chokshi Dave 
Published: August 2022

<p>This case study outlines the sequence of events that resulted in NYC supporting an existing syringe service program (SSP) to open the first two publicly recognized overdose prevention centers in the nation, including lessons learned to inform other jurisdictions considering offering such services. </p>
Sleep Quality among Nursing students in Kathmandu Valley: A Cross-sectional Study
Authors: Regmi Urja , Kunwar Min Bahadur , Acharya Yunika 
Published: August 2022

Introduction: Sleep Quality is an essential component of the learning and memory processes. Nevertheless, sleep issues are common among college students and may negatively impact their academic performance. This study aimed to explore sleep quality among undergraduate nursing students in Nepal.
Methods: We conducted a cross-sectional descriptive study among 267 nursing students from seven colleges located in Kathmandu Valley. A self-administrated questionnaire was distributed among students to assess sleep quality. We used the Pittsburgh Sleep Quality Index (PSQI) to determine sleep quality. Collected data was entered and analyzed in SPSS version 18.
Results: Of total, 97 students (36.3%) were found to have good sleep quality, whereas 170 students (63.7%) were found to have poor sleep quality.
Conclusions: Poor sleep quality was common among nursing students and may have negative effects on both health and academic performance. Nursing students should be actively intervened upon to enhance their sleep hygiene.
Gross-total resection of a suprasellar with recurrent cerebellopontine angle region craniopharyngioma by endoscopic far-lateral supracerebellar infratentorial approach: illustrative case
Authors: Xie Tao , Zhang Xiaobiao 
Published: August 2022

BACKGROUND
Craniopharyngiomas that rarely extend into the posterior fossa are treated with staged operations or combined approaches. The authors reported a patient undergoing gross-total resection of a suprasellar with recurrent cerebellopontine angle (CPA) craniopharyngioma using an endoscopic far-lateral supracerebellar infratentorial approach (EFL-SCITA).

OBSERVATIONS
The patient was a 15-year-old boy who presented with headache and decreased vision that lasted for half a year. He previously received three surgeries related to CPA craniopharyngioma. Preoperative magnetic resonance imaging revealed a suprasellar with recurrent CPA craniopharyngioma. Gross-total resection of this suprasellar and CPA tumor was achieved through EFL-SCITA. All symptoms and signs were improved. There were no postsurgical complications except for mild facial paralysis.

LESSONS
EFL-SCITA can be used not only for tumors in the posterolateral pontomesencephalon and ptero-clival-tentorial area but also for tumors in the suprasellar region with posterior fossa extension.