bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENERAPAN JURNAL BELAJAR DI MASA PANDEMI COVID-19: ANALISIS HASIL BELAJAR PADA MATA KULIAH STRATEGI PEMBELAJARAN (MODEL PEMBELAJARAN BIOLOGI)
Authors: Purbowati Dwi , Adawiyah Rabiatul 
Published: November 2022

Kondisi pandemi memaksa pelaksanaan pendidikan dalam keterbatasan (dengan sistem online). Diterapkan penulisan jurnal belajar untuk membantu mahasiswa merefleksi kembali pengetahuan yang telah diperoleh, meskipun dalam kondisi tanpa tatap muka, mahasiswa tetap dapat memahami kesulitan yang ditemui saat proses pembelajaran. Penelitian ini bertujuan menganalisis penerapan jurnal belajar pada masa pandemi covid-19 terhadap hasil belajar mahasiswa. Jenis penelitian yang dilakukan adalah deskriptif dengan pelaksanaan di semester ganjil 2019/2020. Subjek penelitian adalah mahasiswa semester 5 yang mengikuti mata kuliah strategi pembelajaran (model pembelajaran biologi) yang dibagi menjadi kelas I dan II. Data dikumpulkan, diolah dan dianalisis dengan teknik deskriptif kuantitatif, yakni dengan membandingkan data antara kelas I (dengan jurnal belajar) dengan kelas II (tanpa jurnal belajar) dalam persentase. Hasil penelitian menunjukkan bahwa nilai akhir untuk kelas I adalah A= 48,15 %, A-= 40,74%, dan B+= 11,11 %, sedangkan kelas II dengan nilai A= 32,14%, A-= 51,85%, B+= 3,70%, dan B=11,11%. Dapat disimpulkan bahwa penerapan jurnal belajar di masa pandemi covid-19 memberikan kontribusi positif terhadap perolehan nilai akhir yang lebih baik bagi kelas I dibanding kelas II. Jurnal belajar mampu meningkatkan kemampuan mahasiswa untuk evaluasi diri dan memecahkan masalah yang dihadapinya sehingga mahasiswa dapat melacak kemajuan yang telah dicapainya. The pandemic condition forced the implementation of education in limitations (with an online system). Learning journal writing was applied to help students reflect back on the knowledge that has been obtained, even in non-face-to-face conditions, students can still understand the difficulties encountered during the learning process. This study aimed to analyze the application of learning journal during the covid-19 pandemic on students’ learning outcomes. The type of the conducted study was descriptive with the implementation in the odd semester of 2019/2020 academic year. The study subjects were 5th semester students who took the learning strategy course (biology learning model) which was divided into classes I and II. Data were collected, processed and analyzed by quantitative descriptive technique, namely by comparing the data between class I (with study journal) and class II (without study journal) in percentages.The results showed that the final grades for class I were A= 48.15%, A-= 40.74%, and B+= 11.11%, while for class II were A= 32.14%, A-= 51, 85%, B+= 3.70%, and B=11.11%. It can be concluded that the application of learning journal during the covid-19 pandemic made a positive contribution to the acquisition of better final grades for class I compared to class II. The learning journal was able to improve students' ability to self-evaluate and solve the problems they face so that students can track their progress.
Peran Serta Masyarakat dalam Pengelolaan Sampah Rumah Tangga di Bantaran Sungai Cikapundung Kelurahan Maleer
Authors: Tiaraningrum Noor Biadinanti Putri , Pratama Yulianti 
Published: November 2022

Sungai Cikapundung merupakan salah satu sungai yang berada di Kota Bandung yang saat ini sudah dipadati pemukiman dengan jumlah penduduk 750.559 jiwa. Sungai Cikapundung memiliki panjang aliran sungai sebesar 28 km yang melintasi 11 kecamatan di tiga kabupaten atau kota, yaitu Kota Bandung, Kabupaten Bandung, dan Kabupaten Bandung Barat. Salah satu kecamatan di Kota Bandung yang dialiri oleh Sungai Cikapundung adalah Kecamatan Batunungal yang memiliki 8 kelurahan, salah satunya yaitu Kelurahan Maleer. Kelurahan Maleer memiliki total jumlah penduduk sebanyak 16.770 jiwa pada tahun 2021 dengan kepadatan penduduk sebesar 393 jiwa/Ha. Berdasarkan SNI 03-1733-2004 Kelurahan Maleer masuk ke dalam klasifikasi kawasan berdasarkan kepadatan penduduk tinggi yaitu 201-400 jiwa/Ha. Selain itu, berdasarkan dokumen Rencana Induk Sistem Pengelolaan Sampah Kota Bandung tahun 2017-2037, Kelurahan Maleer juga merupakan kawasan zona prioritas pertama dalam penanganan sampah. hal ini terkait peningkatan jumlah penduduk di Kelurahan Maleer yang akan mempengaruhi timbulan, volume dan jenis sampah yang dihasilkan. Kegiatan membuang sampah ke sungai akan berdampak negatif terhadap kesehatan masyarakat, estetika lingkungan di sepanjang aliran sungai dan sanitasi yang buruk, sehingga peran serta masyarakat sangat penting dalam pengelolaan sampah terutama di daerah bantaran Sungai Kelurahan Maleer. Peran serta masyarakat yang dapat dilakukan dalam pengelolaan sampah yaitu menjaga kebersihan lingkungan, pengurangan sampah, pemberian usul dan saran suatu kegiatan. Keinginan masyarakat yang bersedia berperan aktif dalam pengelolaan sampah sebesar 19%. Namun ada juga masyarakat yang ingin ikut berpastisipasi namun tidak berperan aktif pada kategori low income 16%, kategori middle income 22% dan kategori high income sebesar 16%. Pengurangan sampah terbagi ke dalam dua skenario, dimana pengurangan sampah pada skenario I sebesar 19,50% dan pengurangan sampah pada skenario II sebesar 30%.
Analisis Penentuan Supplier Pada PT. Petro Oxo Nusantara Dengan Kebijakan Zero Inventory Menggunakan Metode Fuzzy Simple Additive Weighting
Authors: Nahar Pratama Adna Belva , Priyana Efta Dhartikasari , Hidayat Hidayat 
Published: November 2022

PT Petro Oxo Nusantara merupakan perusahaan yang memproduksi 2-Ethil Hexanol atau yang lebih sering disebut Octanol. Dimana pada perusahaan ini menerapkan kebijakan zero inventory untuk meminimalisasikan barang inventory sehingga barang yang disimpan tidak terlalu banyak. Penerapan kebijakan zero inventory pada perusahaan, mewajibkan PT. Petro Oxo Nusantara memiliki sistem pendukung kebijakan tersebut. Salah satu sistem pendukungnya adalah pemilihan supplier dengan kriteria paling cocok sesuai kriteria perusahaan. Tujuan penelitian ini adalah untuk menemukan supplier dengan rating tertinggi dan cocok sesuai dengan kriteria perusahaan yaitu : Quality, Cost, Delivery, Specification, dan Service. Metode yang digunakan pada penelitian ini adalah metode Fuzzy Simple Additive Weighting (FSAW). Pengumpulan data dilakukan dengan menyebarkan kuesioner kepada 5 responden divisi logistik. Hasil penelitian menunjukkan bahwa supplier yang memiliki ranking paling tinggi untuk dipilih adalah PT. Air Product Indonesia dengan perolehan nilai sebesar 0,948 untuk supplier gas dan PT. Global Energi Solusindo dengan perolehan nilai sebesar 0,920 untuk supplier sparepart.Kata Kunci: Fuzzy simple additive Weighting, pemasok.
Analisis Kualitas Air Danau Lut Tawar Kabupaten Aceh Tengah Aceh
Authors: Tamara Rima , Barus Ternala Alexander , Wahyuni Hesti 
Published: November 2022

Danau Lut Tawar merupakan sebuah danau dan kawasan wisata yang terletak di kawasan dataran tinggi Gayo (Aceh Tengah). Pemanfaatan danau ini sebagai sumber air bersih, sumber air pertanian, industri, dan perikanan. Kualitas air merupakan komponen lingkungan yang sangat penting sebagai indikator sehatnya suatu daerah perairan. Kualitas air dapat diketahui dengan melakukan pengujian parameter kimia, fisik, dan biologi. Pencemaran perairan dapat terjadi dan menyebabkan perubahan kualitas air apabila masuknya zat atau bahan ke dalam suatu perairan yang dapat mengurangi atau merusak nilai suatu perairan. Penelitian ini bertujuan untuk menganalisis kualitas dan tingkat pencemaran air di Danau Lut Tawar. Penelitian ini merupakan penelitian analisis deskriptif kuantitatif. Pengambilan sampel pada penelitian ini dilakukan secara purposive sampling pada 4 stasiun berdasarkan kegiatan yang ada di sekitar Danau. Hasil Pengukuran kualitas air danau Lut Tawar tidak melebihi nilai ambang batas yang telah ditetapkan berdasarkan baku mutu lingkungan PP 22 Tahun 2021 Lampiran VI. Analisis tingkat pencemaran di Danau Lut Tawar tergolong dalam kategori tercemar sedang berdasarkan metode Indeks STORET dengan menggunakan penilaian status pencemaran perairan. Faktor penyebab pencemaran danau Lut Tawar disebabkan oleh adanya aktifitas budidadya ikan (KJA), pembuangan limbah domestik dan limbah pertanian dari aktivitas masyarakat di sekitar Danau Lut Tawar.
Estudio preliminar de la aplicación de la técnica VMAT en irradiación corporal total: diseño de una camilla rotable
Authors: Pinzón C. Andrés , Simbaqueba Axel , Rodríguez Juan , Veloza Stella , Esguerra C. José 
Published: November 2022

La irradiación corporal total (TBI, por sus siglas en inglés) es una terapia previa al trasplante de médula ósea en la que se administra una dosis de radiación uniforme en todo el cuerpo del paciente, que busca minimizar la dosis entregada en diferentes órganos como pulmones y, en algunas ocasiones, riñones [1]. En Colombia la TBI con rayos X generados por acelerador lineal se realiza con la técnica convencional, en la cual el paciente mantiene una posición anatómica de pie, fetal o decúbito lateral durante tiempos de irradiación prolongados, lo cual implica que la posición de tratamiento para el paciente sea incómoda y poco reproducible; adicionalmente su implementación requiere distancias fuente/paciente de hasta 4 metros y la construcción de protecciones personalizadas [2]. Con el fin de superar estas dificultades, el Instituto Nacional de Cancerología (INC) tiene el objetivo de desarrollar un protocolo para administrar la TBI empleando arcoterapia volumétrica de intensidad modulada (VMAT). Con esta técnica de optimización inversa se ha reportado una entrega de dosis de radiación más uniforme en todo el cuerpo del paciente en comparación con la técnica convencional, y una reducción de la dosis recibida por los órganos en riesgo (OAR) [3]; adicionalmente su implementación no requiere grandes áreas en la sala de tratamiento, ya que se realiza a distancias estándar fuente/isocentro. En este artículo se presenta un estudio preliminar del protocolo de TBI/VMAT y su validación, mediante el empleo de un simulador anatómico CIRS: la construcción de una camilla rotable para ser superpuesta a la mesa del acelerador y tomógrafo, que facilita el cambio de orientación craneocaudal del paciente a caudocraneal durante el tratamiento, recomendaciones para la inmovilización del paciente sobre la camilla rotable, la obtención de imágenes de tomografía computarizada de cuerpo completo mediante fusión de imágenes parciales, la planeación del tratamiento con múltiples isocentros y múltiples arcos para el cálculo de la dosis absorbida y la verificación del tratamiento con superposiciones de medidas de dosis en el software SNC Patient tomadas con detectores en el dispositivo ArcCheck en diferentes orientaciones.
Understanding the environmental drivers of clinical azole resistance in Aspergillus species
Authors: Sen Pooja , Vijay Mukund , Singh Shweta , Hameed Saif , Vijayaraghvan Pooja 
Published: November 2022

Aspergilli are ubiquitous fungal pathogens associated with severe life-threatening infections, especially in immunocompromised patients. Azoles are the first line of defence in the fight against most Aspergillus -related infections. However, resistance to these therapeutic compounds has developed, which is mainly due to the existence of mutations in lanosterol 14 alpha-demethylase (Cyp51A), a crucial enzyme in the pathway that produces ergosterol and is the target of azole antifungals. Azole-based antifungal medications are ineffective because of infections brought on by azole-resistant Aspergillus species, leading to a high fatality rate. However, resistant Aspergillus isolates have also been isolated from azole-naïve patients. Global agricultural practices promote the use of azole fungicides to protect crops from phytopathogens. Usage of azole fungicides on a large scale has been linked to the development of resistance among Aspergillus species prevalent in the environment. The infections caused by these azoleresistant Aspergillus species cannot be treated by the available azole drugs, in turn leading to high morbidity and mortality rates. Thus, knowledge of the environmental drivers and comprehending the genetic basis of fungal drug resistance evolution is pertinent, considering increasing numbers of patients with COVID-19 infections who are sensitive to opportunistic fungal infections. This article emphasises the prevalence and underlying mechanisms of azole resistance in Aspergillus species, with a focus on environmental triggers and resistance development. It also highlights the need for regular surveillance of pesticide use in agriculture, detection of triazole-resistant Aspergillus species in environmental and clinical settings and development of new antifungal drugs.
Cyto- and bio-compatibility assessment of plasma-treated polyvinylidene fluoride scaffolds for cardiac tissue engineering
Authors: Kitsara Maria , Revet Gaëlle , Vartanian-Grimaldi Jean-Sébastien , Simon Alexandre , Minguy Mathilde , Miche Antoine , Humblot Vincent , Dufour Thierry , Agbulut Onnik 
Published: November 2022

As part of applications dealing with cardiovascular tissue engineering, drop-cast polyvinylidene fluoride (PVDF) scaffolds have been treated by cold plasma to enhance their adherence to cardiac cells. The scaffolds were treated in a dielectric barrier device where cold plasma was generated in a gaseous environment combining a carrier gas (helium or argon) with/without a reactive gas (molecular nitrogen). We show that an Ar-N2 plasma treatment of 10 min results in significant hydrophilization of the scaffolds, with contact angles as low as 52.4° instead of 132.2° for native PVDF scaffolds. Correlation between optical emission spectroscopy and X-ray photoelectron spectroscopy shows that OH radicals from the plasma phase can functionalize the surface scaffolds, resulting in improved wettability. For all plasma-treated PVDF scaffolds, the adhesion and maturation of primary cardiomyocytes is increased, showing a well-organized sarcomeric structure (α-actinin immunostaining). The efficacy of plasma treatment was also supported by real-time PCR analysis to demonstrate an increased expression of the genes related to adhesion and cardiomyocyte function. Finally, the biocompatibility of the PVDF scaffolds was studied in a cardiac environment, after implantation of acellular scaffolds on the surface of the heart of healthy mice. Seven and 28 days after implantation, no exuberant fibrosis and no multinucleated giant cells were visible in the grafted area, hence demonstrating the absence of foreign body reaction and the biocompatibility of these scaffolds.
The association between implementation of multidisciplinary rounds and clinical outcomes
Authors: Sreepathy Pranati , Kim Yoo Jin , Ahuja Zaneta , Shroff Adhir R. , Nazir Noreen T. 
Published: November 2022

BackgroundMultidisciplinary rounds (MDR) consisting of social workers, dietitians, pharmacists, physical therapists, nurses, and physicians have been implemented at many healthcare institutions to address the complex components of inpatient care. However, little is known on the association of MDR on clinical outcomes across cardiovascular pathologies. This study aimed to investigate the impact of MDR on cardiovascular patients.MethodsHospital admissions to inpatient cardiology were evaluated prior to (November 2017 to November 2018) and after implementation of MDR (December 2018 to August 2020) at a metropolitan academic medical center. The following outcomes were evaluated: clinical complications (incidence of stroke, gastrointestinal bleed, myocardial infarction, or systemic infection during hospitalization), Length of Stay (LOS), 30-day readmissions and all-cause in-hospital mortality. Secondary outcomes included utilization of physical therapy and dietary services.ResultsAdmissions were evaluated prior to (N = 1054) and after (N = 1659) MDR implementation. All-cause in-hospital mortality after MDR implementation decreased significantly from 2.8 to 1.6% (P = 0.03). Although the number of complications and LOS decreased, these differences were not statistically significant. No significant change was observed in 30-day readmissions. Significant increase in the utilization of physical therapy (34.2 to 53.5%; P &lt; 0.01) and dietary services (7.2 to 19.3%; P &lt; 0.01) were observed.ConclusionMultidisciplinary rounds implementation was associated with significantly decreased mortality and positively impacted resource utilization with increased consultations for ancillary services. MDR is a high impact intervention that utilizes existing resources to improve mortality and should be implemented especially for cardiovascular patients. Further investigation into the benefit of MDR across different patient populations and care settings is warranted.
Case report: Refractory cardiac arrest supported with veno-arterial-venous extracorporeal membrane oxygenation and left-ventricular Impella CP®–Physiological insights and pitfalls of ECMELLA
Authors: Thevathasan Tharusan , Füreder Lisa , Donker Dirk W. , Nix Christoph , Wurster Thomas H. , Knie Wulf , Girke Georg , Al Harbi Abdulla S. , Landmesser Ulf , Skurk Carsten 
Published: November 2022

IntroductionTo the best of our knowledge, this is the first case report which provides insights into patient-specific hemodynamics during veno-arterio-venous-extracorporeal membrane oxygenation (VAV ECMO) combined with a left-ventricular (LV) Impella®micro-axial pump for therapy-refractory cardiac arrest due to acute myocardial infarction, complicated by acute lung injury (ALI).Patient presentationA 54-year-old male patient presented with ST-segment elevation acute coronary syndrome complicated by out-of-hospital cardiac arrest with ventricular fibrillation upon arrival of the emergency medical service. As cardiac arrest was refractory to advanced cardiac life support, the patient was transferred to the Cardiac Arrest Center for immediate initiation of extracorporeal cardiopulmonary resuscitation (ECPR) with peripheral VA ECMO and emergency percutaneous coronary intervention using drug eluting stents in the right coronary artery. Due to LV distension and persistent asystole after coronary revascularization, an Impella®pump was inserted for LV unloading and additional hemodynamic support (i.e., “ECMELLA”). Despite successful unloading by ECMELLA, post-cardiac arrest treatment was further complicated by sudden differential hypoxemia of the upper body. This so called “Harlequin phenomenon” was explained by a new onset of ALI, necessitating escalation of VA ECMO to VAV ECMO, while maintaining Impella®support. Comprehensive monitoring as derived from the Impella®console allowed to illustrate patient-specific hemodynamics of cardiac unloading. Ultimately, the patient recovered and was discharged from the hospital 28 days after admission. 12 months after the index event the patient was enrolled in theECPR Outpatient Care Programwhich revealed good recovery of neurologic functions while physical exercise capacities were impaired.ConclusionA combined mechanical circulatory support strategy may successfully be deployed in complex cases of severe cardio-circulatory and respiratory failure as occasionally encountered in clinical practice. While appreciating potential clinical benefits, it seems of utmost importance to closely monitor the physiological effects and related complications of such a multimodal approach to reach the most favorable outcome as illustrated in this case.
The lipid accumulation product is a powerful tool to diagnose metabolic dysfunction-associated fatty liver disease in the United States adults
Authors: Li Hejun , Zhang Ying , Luo Hengcong , Lin Rong 
Published: November 2022

Background &amp; objectivesBody mass index (BMI) and waist circumference (WC) are widely used to assess obesity, but they are limited in their ability to distinguish complicated body metabolic situations (fat mass, lean body mass, visceral and subcutaneous fat deposits in the abdomen). The purpose of this study was to evaluate the diagnostic efficacy of different anthropometric indices in metabolic dysfunction-associated fatty liver disease (MAFLD) and to identify the best cut-off point for the diagnosis of MAFLD in United States adults.MethodsA cross-sectional study among 4,195 participants over 18 years old in the National Health and Nutrition Examination Survey (NHANES) 2017–2018 was performed. All patients underwent vibration controlled transient elastography (VCTE). Assess the anthropometric measurements, including BMI, WC, waist-to-height ratio (WHtR), waist-to-hip ratio (WHR), cardiometabolic index (CMI), triglyceride-glucose (TyG) index, hepatic steatosis index (HSI), lipid accumulation product (LAP), body roundness index (BRI), visceral fat index (VAI), abdominal volume index (AVI), cone index (CI), and body fat index (BAI). Logistic regression analyses were conducted to estimate the impact of these indices, on the odds ratio (OR) values of MAFLD. Receiver operator characteristic (ROC) analyses were performed to assess the diagnosing capacity of these anthropometric indices for MAFLD and identify the optimal cut-offs points.ResultsA total of 4,195 (2,069 men and 2,126 women) participants were performed, with 45.4 ± 0.64 (mean ± SD) years old. All anthropometric metrics were positively associated with MAFLD, irrespective of whether it was treated as continuous or categorical variable (P&lt;0.05). Multivariate logistic regression showed a positive correlation between AVI, HSI, WHtR, BRI, and MAFLD, with significant interaction with gender. ROC curves results showed that LAP had the highest AUC [0.813 (95% CI, 0.800–0.826)], especially in participants aged between 18 and 50 years old. Furthermore, LAP showed the highest ROC in both the training set [0.812 (95% CI, 0.800–0.835)] and the validation set [0.809 (95% CI, 0.791–0.827)].ConclusionsIn the present study, we showed that those anthropometric indices were significantly associated with MAFLD in United States adults. Besides, the association of HSI, BRI, AVI, and WHtR with MAFLD was more obvious in men than in women. LAP may be a sensitive marker for diagnosing MAFLD in U.S. adults.
What are we protecting? An analysis of the current conservation framework addressing Mediterranean mesophotic habitats
Authors: Castellan G. , Abbiati M. , Angeletti L. , Foglini F. , Grande V. , Montagna P. , Taviani M. 
Published: November 2022

Mesophotic ecosystems in the Mediterranean Sea are biodiversity hotspots distributed from ca 30 m down to 180 m, depending upon the depth of the light compensation point. Overall, the taxonomic composition of Mediterranean mesophotic ecosystems is dominated by corals and sponges, with subordinate bryozoans, mollusks, ascidians, and shade-adapted algae. As for most marine ecosystems, the mesophotic habitats are increasingly exposed to natural and anthropogenic threats, including seawater-temperature rise, more intense and frequent heat waves, progressive ocean acidification, fishing activities, and littering. The establishment of effective governance guidelines is, therefore, the necessary rationale to guarantee the good environmental status of such widespread, highly diverse, service-provider natural resources. However, an in-depth quantification of the extent to which Mediterranean mesophotic habitats and taxa are included in conservation measures is lacking. In this article, we review the available literature information on mesophotic habitats in the Mediterranean Sea to evaluate the efficiency of the current legislative framework in providing instruments to protect this natural heritage. Our analysis allows identifying gaps in the current conservation network, ultimately suggesting functional integrative actions for effective conservation measures and the long-term survival of the Mediterranean mesophotic ecosystems.