bluuebunny/crossref_metadata_2025_split huggingface dataset:
25% Dextrose Versus 24% Sucrose for Heel Lancing in Preterm Infants: A Noninferiority RCT
Authors: Sasidharan Rohit , Gupta Neeraj , Yadav Bharti , Chawla Deepak , Singh Kuldeep , Kumarendu Singh Arun 
Published: April 2022

OBJECTIVES
To compare the efficacy of 25% dextrose with 24% sucrose for heel-lance analgesia in preterm infants admitted to the NICU.

METHODS
In this noninferiority, double-blind, randomized controlled trial, preterm infants born at 28 weeks and 0 days to 35 weeks and 6 days of gestation who were due for a scheduled heel-lance procedure were enrolled. Infants randomly assigned to the intervention arm received 0.5 mL 25% dextrose, whereas infants in the active control group received 0.5 mL 24% sucrose orally just 2 minutes before the heel-lance procedure. The primary outcome was Premature Infant Pain Profile (PIPP) score 30 seconds after the procedure. Secondary outcomes included PIPP scores at 60 and 120 seconds, PIPP-Revised scores at 30, 60, and 120 seconds, and any adverse events.

RESULTS
Sixty-four infants were enrolled (32 in each group). The mean (SD) PIPP score at 30 seconds was 6.41 (2.56) in the dextrose group and 7.03 (2.23) in the sucrose group (mean difference, −0.63 (95% confidence interval, −1.85 to 0.60; P = .31). The upper margin of the confidence interval did not cross the predefined noninferiority margin of 2. The mean PIPP scores at 60 (5.03 [2.18] vs 5.39 [1.48]) and 120 (4.75 [1.97] vs 4.94 [1.46]) seconds were also similar. The PIPP-Revised scores between the 2 groups at all time intervals were comparable. One infant in the intervention group had a transient coughing episode.

CONCLUSIONS
In preterm infants under intensive care, 25% dextrose is noninferior to 24% sucrose for heel-lance analgesia as assessed by PIPP score.
Uma entrevista com o escritor José Falero
Authors: Botton André Natã Mello 
Published: April 2022

Nesta entrevista, o escritor gaúcho José Falero, autor do livro de contos Vila Sapo (2019), do romance Os supridores (2020) e do livro de crônicas Mas em que mundo tu vive? (2021), resgata aspectos de sua vida, relembra diversas experiências e a sua relação estabelecida com o espaço urbano de Porto Alegre; além disso, também expõe como se dá o seu processo de escrita e apresenta suas principais influências de leitura. Com isso, o objetivo desse diálogo é estabelecer um espaço possível de escuta de um agente emergente no campo literário brasileiro e que tem se consolidado nesse meio como um dos mais relevantes escritores na contemporaneidade. Desse modo, José Falero traz em suas respostas importantes reflexões sobre o contexto social brasileiro, sobre sua prática de escrita, sobre a literatura brasileira e sua visão de mundo.
Development and characterisation of functional cultured buttermilk fortified with flaxseed
Authors: Mahmoudi I. , Ben Moussa O. , Chouaibi M. , Telmoudi A. , Boukari W. , Hassouna M. 
Published: April 2022

Abstract
Cultured buttermilk is a dairy beverage with a high nutritive value. In the current study, functional cultured buttermilk was formulated using probiotic Lactobacillus plantarum and flaxseed fortification to improve the potential health benefits. The cultured buttermilk samples were analysed for pH, lactic acidity, colour, phase separation, viscosity, microbiology and sensory properties. The results showed non-significant changes in acidity and pH. However, flaxseed fortification decreased phase separation and increased viscosity of buttermilks. In addition, a significant difference in colour attributes was revealed between samples. Sensory characteristics of cultured buttermilks were acceptable to produce a functional food.
estrés académico en estudiantes de gastronomía de una universidad privada de la ciudad de Durango, en México
Authors: Barraza Macías Arturo , Medina Gandara Salma Yanice 
Published: April 2022

Los principales objetivos de esta investigación son Identificar el estrés académico de los alumnos de una licenciatura en gastronomía, vía sus componentes sistémico procesuales, y determinar la relación que existe entre el estrés académico de los alumnos de una licenciatura en gastronomía y sus variables sexo, edad, semestre que cursa, relación de pareja y si trabaja demás de estudiar. Para el logro de esos objetivos se llevó a cabo un estudio correlacional, no experimental y transversal a través de la aplicación del Inventario SISCO para el estudio del estrés académico a 95 alumnos de la Licenciatura en Gastronomía en una universidad privada. Sus principales resultados indican la presencia de un estrés moderado y la no relación con las variables sociodemográficas.
THE EFFECT OF ORBICULARIS OCULI SLING ON LATERAL CANTHUS AND LOWER LID IN UPPER BLEPHAROPLASTY
Authors: Ali Paiwand , Qader Ari , Hasan Hawree , Rasul Faraydoon , Hiwa Vyan 
Published: April 2022

Background
Upper lid blepharoplasty is one of the most commonly performed procedures in aesthetic plastic surgery, which directly affects facial rejuvenation. The periocular region is the main point of focus in routine face-to-face interaction. Understanding the periorbital surgical anatomy, facial analysis, and specific change in the skin, muscle and fat with preoperative workup and a thoughtfully conceived surgical plan targeted according to the difference gives a successful outcome.
Objectives
This dynamic region has both functional and aesthetic influence on the face; unfortunately, this area develops ageing sooner than other regions of the face.
Patients and Methods
A total of 30 patients underwent upper lid blepharoplasty. In the most lateral part, the orbicularis oculi muscle was divided horizontally. The lower part was suspended to the periosteum of the orbital rim with a single stitch of the long-standing absorbable suture. The upper part overlapped over the lower part of the muscle and fixed them by a single stitch in a single stitch pant over vest fashion.
Results
This technique provides more youthfulness to the eye, especially at the region of lateral canthus, as it lifts the tissue superolateral. It has minimal effect on lateral canthus laxity but shows marked improvement in lateral lower lid and crowfeet; it also shows valuable improvement of lateral hooding.
Conclusion
The orbicularis oculi muscle suspension procedure is a good technique that reliably corrects and reshapes the outer portion of both upper and lower eyelids. It is an easy technique, and it would be helpful as an adjunctive procedure with blepharoplasty in selected cases.
DYSAUTONOMIA FOLLOWING ACUTE ISCHEMIC STROKES: A SINGLE INSTITUTIONAL EXPERIENCE
Authors: Shekhbzeni Aso 
Published: April 2022

Background
Many studies have found that patients with ischemic stroke can develop autonomic system disturbances, affecting the heart, causing different types of arrhythmias and even sudden death.
Objectives
To analyze the occurrence of cardiovascular autonomic dysfunction and cardiac arrhythmias after acute ischemic stroke.
Patients and Methods
This case-controlled study was conducted at the Rizgary Teaching Hospital from July 1st, 2018, to September 30th, 2019. Fifty patients with acute ischemic stroke were enrolled consecutively and were age-matched and gender-matched with a group of 50 individuals (control group). Four bedside autonomic function tests (deep breathing, heart rate response to standing, isometric handgrip test, and blood pressure response to standing) were used to assess autonomic dysfunction during the acute post-stroke phase. In addition, all patients and controls underwent 24-hour Holter cardiac monitoring.
Results
Although abnormal autonomic function testing was more frequent in post-stroke cases than in healthy controls, there was no statistically significant difference in these results among stroke sub-groups. There were more arrhythmias in patients with stroke in comparison with the control group; premature ventricular and atrial contractions were more frequent in stroke patients than in the control group (P-value <0.001 and P-value<0.001, respectively).
Conclusion
Cardiac dysautonomia is common in patients with acute ischemic stroke, and cardiac dysrhythmias are commonly encountered in patients with insular infarctions. Whether these dysrhythmias are life-threatening or not, further analytic studies are required to uncover their clinical significance.
THE EFFECT OF A VERY SHORT INTERPREGNANCY INTERVAL AND PREGNANCY OUTCOMES FOLLOWING A PREVIOUS PREGNANCY LOSS
Authors: Rahman Renas , Fattah Chro 
Published: April 2022

Background Interpregnancy interval is a modifiable risk factor for adverse outcomes in infants and their mothers. The World Health Organization proposed that women wait a minimum of twenty-four months following a live birth and six months following a miscarriage before conceiving again. Objectives The aim is to assess the outcome of pregnancy and complications correlated with an interpregnancy interval following a prior pregnancy loss. Patients and Methods This is a prospective comparative study that includes 100 patients in a maternity teaching hospital in Sulaymaniyah - Iraq, between April 2020 to March 2021, divided into two groups of 50 patients each, as groups A and B. One group has an interpregnancy interval <3 months and the other group has interpregnancy interval ≥ 3 months. This study included women whose final reproductive outcomes were a pregnancy loss and afterwards became pregnant. The study outcome included the outcome of the pregnancy, whether delivered by caesarian section or vaginal delivery, the outcome of the baby including birth weight and APGAR score in 1 minute and 10 minutes, and whether admitted to the Neonatal Care Unit or not. The outcome also included the pregnancy complications such as pregnancy loss, type of the pregnancy loss, and complications of the pregnancy (pre-eclampsia, gestational diabetes, and preterm birth <37weeks). Results The pregnancy outcomes turned out as 76 cases of live births, and 24 cases of miscarriage. From live births, 58 cases were delivered vaginally, and 18 cases were delivered by caesarean section. Conclusion This study showed that conception within 12 weeks of prior miscarriage, was not related to an increased liability of poor pregnancy outcomes.
Perioperative management of patients with post Covid rhino-orbito-cerebral mucormycosis: Prospective observational study
Authors: Kalarthi Bhoomika , Desai Devyani , Shah Neha , Cheraya Neha , Bavisetti Sagar , D Parvathy , Zala Abhishek , Choube Kanchan , Cheraya Gaurav 
Published: April 2022

Mucormycosis is a life-threatening, locally invasive, rapidly progressive, opportunistic fungal infection, associated with several anaesthetic challenges.We aimed to study its relation with patient’s comorbidities, covid treatment strategies, also to observe the intubation difficulties, changes in hemodynamic parameters, post anaesthesia recovery status and perioperative complications.In this time bound study, total 160 patients were included. During pre-anaesthetic evaluation, presence of associated co-morbidities, course of Covid-19 disease, requirement of O2 therapy were noted. On the day of surgery, premedications and sedation were given. Induction was done with propofol/etomidate along with sevoflurane/desflurane. Intubation was done with succinyl choline/ atracurium and difficulties in intubation were graded according to Modified Intubation Difficulty Scale. Anaesthesia was maintained with the mixture of Oxygen, Air and inhalation agent along with intermittent Atracurium. Hemodynamic parameters, intra operative and post operative outcome were noted. Unstable patients were shifted to intensive care unit.Among patients of rhino-orbito-cerebral mucormycosis, most common co morbidity found was diabetes mellitus (42%). Here, 61% were on room air, rest needed oxygen therapy. Total 52% patients required &#62;/= 2 intubation attempts, in which 9% were video laryngoscope assisted and 11% required additional maneuvers. 22% patients were started on intravenous nitroglycerin to manage intraoperative hypertension. 9.3% patients required ICU admission, of which 2.5% could not survive.Possibilities of developing rhino-orbito-cerebral mucormycosis in patients having diabetes mellitus are high. The anaesthetic management requires eternal vigilance to encounter difficult intubation, delayed recovery, and higher rate of morbidity and mortality.
IMPACT OF FEAR OF COVID – 19 ON SMARTPHONE ADDICTION AND MENTAL HEALTH PROBLEMS (ANXIETY, DEPRESSION, AND STRESS) AMONG YOUNG ADULTS
Authors: Bukhari Syeda Razia , Riaz Komal , Tabassum Shafia , Nisar Ayesha 
Published: April 2022

Purpose of the study: The main objective of the current study was to look at the impact of fear of covid–19 and Smartphone addiction on mental distress.
Methodology: Effectively using purposive sampling from the twin cities Islamabad and Rawalpindi, the current study comprises 339 participants, out of which 179 were males and 160 female (18 – 69 years). A standardized measuring instrument (fear of Covid-19 scale) was utilized to self-report data gathering and other tools such as the smartphone addiction scale and psychological distress scale.
Main Finding: The results showed that fear of a novel pandemic had a substantial impact on depression (B=0.265, p=.000), anxiety (B=0.194, p=.000), and stress (B=0.153, p=.004), respectively. Fear of Coronavirusalso has a noteworthy impact on Smartphone addiction (B=0.497, p=.000). The findings recommended that elevated fear of the Pandeicis directly related to high mental distress by positively affecting the populace's emotions and behavior.
Application of the study: Psychological well-being administrations given in the hour of the continuous COVID-19 Pandemic ought to be coordinated to help in fostering familiarity with sensations of dread and to elevate encountering these sentiments to exceptional levels. One among the cornerstones of psychosocial support administrations could likewise be creating abilities related to enthusiastic mindfulness, working on the ability to deal with sentiments and taking care of pressure and nervousness.
Novelty/ Originality of the study: The present study examines the impact of fear of COVID-19 on excessive smartphone usage and mental health problems. This review will give critical commitment to the significant writing concerning a portion of the mental impacts emerging as an outcome of the novel pandemic.
O MODELO ADDIE EM UM PROJETO DE FORMAÇÃO PROFISSIONAL: possibilidades para a Administração Pública
Authors: Scheyla Joanne Horst  , Maria Aparecida Crissi Knuppel  , João Angelo Pires da Silva  , Giovane Galvão  
Published: April 2022

Dentro das abordagens do Design Instrucional para cursos massivos on-line, um modelo bastante conhecido é o da sigla ADDIE, que contempla as fases de Análise, Design, Desenvolvimento, Implementação e Avaliação. Cada etapa possui suas características e objetivos, e, quando há um planejamento estruturado, é possível criar formações que respondam às necessidades pontuais do público-alvo em uma sociedade que demanda atualizações em diferentes áreas. O relato de experiência aqui apresentado contempla um caso de Design Instrucional fixo, com a elaboração de cursos autoinstrucionais referentes à atuação de setores de uma instituição pública do estado do Paraná, contando com o envolvimento de equipes multidisciplinares na produção e reflexões a respeito das etapas. O projeto foi elaborado no âmbito da Universidade Virtual do Paraná (UVPR), por meio do Núcleo de Educação a Distância da Universidade Estadual do Centro-Oeste (Unicentro). Constata-se que o trabalho conjunto pode resultar em uma proposta que evidencia o papel da universidade pública como propulsora de projetos educativos inovadores e que atendam a formatos que se inserem na educação digital. De tal forma, quando bem compreendido pelos autores, o modelo ADDIE pode contribuir para a formação na Administração Pública de maneira aberta e contínua, em tempos que exigem essa capacitação constante.
Palavras-chave: Design Instrucional. Cursos abertos. Educação digital. Formação profissional continuada.
Experiencia inédita de enseñar via remota procedimientos restauradores directos e indirectos a través de la plataforma Zoom usando el modelo de simulación personalizado en tiempos de COVID-19.
Authors: Saravia-Rojas Miguel Á. , Cupe-Mamani Britney 
Published: April 2022

La COVID-19 y la continuidad de la emergencia sanitaria han generado que durante el 2021 se mantenga el distanciamiento social y los cuidados en el aforo de los espacios públicos. Esto ha ocasionado que la presencialidad a clases aún se vea afectada, obligando a que las instituciones de educación superior continúen via remota sus actividades. La carrera de odontología es eminentemente práctica, en ese sentido muchos de los cursos tuvieron que experimentar una adecuación a esta nueva contingencia. En el presente artículo se presentan las adecuaciones, estrategias y metodologías aplicadas en dos cursos de carrera eminentemente clínicos que se imparten en el sexto y séptimo ciclo de la carrera de odontológia de la Facultad de Estomatología de la Universidad Peruana Cayetano Heredia, denominados Clínica Integral del Adulto III y Clínica Integral del Adulto IV que se imparten en el primer y segundo semestre de cada año. Se muestra cómo se llevaron a cabo estos cursos vía remota y usando un modelo de simulación personalizado (Maqueta-UPCH) con el objetivo de llevar a cabo la adquisición de competencias por parte de los alumnos. Esta es una experiencia inédita nunca antes descrita a la fecha.
Ecological impacts of the African sharptooth catfish Clarias gariepinus in the Guapi-Macacu, a River in the Guapimirim Environmental Protection Area, southeastern Brazil
Authors: Dumith Michelle Torres , Santos Alejandra FGN 
Published: April 2022

Abstract
The African sharptooth catfish (Clarias gariepinus) is the most important catfish species for aquaculture. It has great capacity to endure several stressing factors, such as adverse environmental conditions, as well as a broad feeding flexibility. Notwithstanding, the presence of this alien fish in the Guapimirim Environmental Preservation Area, in Southeast of Brazil, may generate negative impacts on the community of native fish. In 2018, during dry and rainy seasons, samples from the fish community were collected in thirty-two sites of the Guapi-Macacu River, and the abiotic variables (salinity, pH, temperature, turbidity, dissolved oxygen, and transparency) were assessed to diagnose which factors influence in the distribution of the alien fish along the river. Moreover, species within the ichthyofauna were evaluated as bioindicators to identify possible alterations in the community. Multivariate analyzes indicated that the African sharptooth catfish dominates the buffer zone of the environmental protection area, benefiting from higher levels of dissolved oxygen and temperature. However, C. gariepinus still do not dominate the most protected area of Guapimirim, where a higher percentage of native fish species dwell. The alterations in abiotic factors, related to the increase in the temperature, may significantly contribute to the domination of this invading alien fish in this protected area, being necessary the constant monitoring of some key species, as well as the population of the invading species in this environmental preservation area.
Anti-larvicidal antimicrobial and cytotoxic effect of endophytic fungus Alternaria macrospora isolated from Trichillia connaroides
Authors: Chinnasamy Ragavendran , Govindasamy Balasubramani , Cherian Tijo , Devarajan Natarajan 
Published: April 2022

Abstract
The interaction of plants with microorganisms at various trophic levels is primarily for growth, development and deterrence and is intertwined in a complex network of inhabitants. Endophytes of fungal origin are widely recognized for supporting the production of host plant defence systems, new secondary metabolites, biological pest control agents, and beneficial colony-forming fungi. This study focuses on the assessment of the biological activity of the endophyte, Alternaria macrospora isolated from the leaves of Trichillia connaroides. This strain was genotyped by amplification of the internal transcribed spacer (ITS) gene region. Chemical profiling of the extract is performed by gas chromatography-mass spectrometry (GCMS), indicating the presence of functional groups by FTIR peaks. In addition, A. macrospora metabolites exhibit biological activity listed as antibacterial, antifungal, larval killing, and anticancer activities. It provides a catalogue of bioactivity that is highly relevant to drug and pharmacological settings.
Dynamic community discovery algorithm for large-scale mobile communication networks
Authors: Liu FengHua , Zhao XuMing , Liu Fangyuan , Chen ZhenZhen , Shen Li , Zhu MengLi 
Published: April 2022

Abstract
A mobile communication network usually has a complex system composed of millions of connected mobile devices, each device can be regarded as a node, and the communication between them can be regarded as an edge. Because the structure of mobile communication networks always changes with time, such as the appearance or disappearance of device nodes or edges, the traditional method of researching mobile communication network structure modelling becomes a very challenging problem. This paper constructs a dynamic community detection model based on representation learning (DCDAL) based on graph autoencoding and the Gaussian mixture depth model in response to the above problems. Commonly used dynamic network evaluation indicators such as NMI and modularity are compared and analyzed in complex communication networks. The DCDAL model can outperform the optimal comparative models in NMI and other indicators, especially in large-scale mobile communication network datasets. The model can obtain robust results on multiple indicators Text for this section.
Copolymer-MnO2 nanocomposites for the adsorptive removal of organic pollutants from water
Authors: Kalarikkandy Arun Viswan , S Nirmal , Ravichandran Sanjay , Dheenadayalan Gangadharan 
Published: April 2022

Abstract
The copolymer beads prepared by suspension polymerization were decorated with MnO2 nanoparticles and successfully implemented for the efficient removal of toxic organic contaminants from water. Copolymer-MnO2 nanocomposite was further analysed using XRD, SEM, and optical microscope. The SEM images showed the surface characteristics of MnO2 nanoparticles on copolymer beads. The efficiency of the copolymer-MnO2 nanocomposite for the removal of model pollutant methylene blue and rhodamine B is then analysed by changing the concentration of pollutant. The results obtained exhibited 18.45 mg/g for methylene blue adsorption and 3.125 mg/g for rhodamine B. The adsorption equilibrium results were fitted to Langmuir adsorption isotherm for both methylene blue and rhodamine B adsorption. The desorption studies were performed for five consecutive cycles and material was showing good regenerating capacity towards both organic pollutants. The obtained results show that copolymer-MnO2 nanocomposite is an efficient material for the removal of organic contaminants from wastewater.