bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ameliorative effects of endogenous and exogenous indole-3-acetic acid on atrazine stressed paddy field cyanobacterial biofertilizer Cylindrospermum stagnale
Authors: Ahmad Nazia , Yasin Durdana , Bano Fareha , Fatma Tasneem 
Published: July 2022

AbstractAcross the world, paddy fields naturally harbour cyanobacteria that function as biofertilizers and secrete various compounds like Indole-3-acetic acid (IAA) that help organisms in regulating their growth. Also, paddy field farming utilizes large amounts of pesticides (e.g. atrazine); but their continued application in the agricultural field causes toxicity in non-target cyanobacterial species that hinder their performance as a biofertilizer. Hence, the current study is an attempt to ameliorate the atrazine stress in cyanobacterium Cylindrospermum stagnale by addition of IAA (1 mM each) under different atrazine levels (0, 60, 80, 100, 120, 140 µg/l). Atrazine toxicity affected C. stagnale in a dose-dependent manner further experiments revealed that both the exogenous and endogenous IAA mitigated the detrimental effects of atrazine. It reduced MDA content and simultaneously increased chlorophyll content, total protein content, and multiple antioxidant enzyme activities [superoxide dismutase (SOD), catalase (CAT), and ascorbate peroxidase (APX)] at 140 µg/l. A molecular docking study revealed that the pesticide binds to the D1 protein of the photoelectric chain in photosynthesis. Hence, the application of IAA or cyanobacterial biofertilizer that secretes a sufficient amount of IAA may assist sustainable agriculture in counteracting the atrazine toxicity.
Effect of modified Total Body Recumbent Stepper training on exercise capacity and thioredoxin in COPD: a randomized clinical trial
Authors: Duan Wentao , Zeng Dan , Huang Jin , Gu Jing , Li San , Zhou Wei , Ma Jinling , Jiang Yan , Zhu Liming , Xiang Xudong , Dai Aiguo 
Published: July 2022

AbstractExercise intolerance is one of the major symptoms of chronic obstructive pulmonary disease (COPD). Exercise training can benefit COPD patients, but the underlying mechanism remains unclear. The modified Total Body Recumbent Stepper (TBRS, Nustep-T4) can benefit patients with stroke, spinal cord injury and amyotrophic lateral sclerosis. Nevertheless, the effect of TBRS training alone on pulmonary rehabilitation (PR) in COPD patients remains largely unknown. We aimed to explore the effect of TBRS training on exercise capacity and the thioredoxin system (TRXS) in COPD patients to provide a novel rehabilitation modality and new theoretical basis for PR of COPD patients. Ninety stable COPD patients were randomly divided into a control group (NC group) and a TBRS training group (TBRS group), with 45 cases in each group. Subjects in the TBRS training group were scheduled to undergo TBRS endurance training triweekly for 12 weeks under the guidance of a rehabilitation therapist. We assessed the primary outcome: exercise capacity (6-min walking distance, 6MWD); and secondary outcomes: perception of dyspnoea (mMRC, Borg), the COPD assessment test (CAT), the BODE index, pulmonary function, the number of acute exacerbations of COPD and oxidative stress (TRXS) at one-year follow-up. Compared with before the intervention and the control group, after the intervention, the TBRS training group, exhibited an increase in the 6MWD (from 366.92 ± 85.81 to 484.10 ± 71.90, 484.10 ± 71.90 vs 370.63 ± 79.87,P < 0.01), while the scores on the BORG, mMRC, BODE index, CAT, and the number of acute exacerbations of COPD were reduced, and the protein and mRNA expression levels of TRXS was significantly increased (P < 0.01). However, no differences were found in PF parameters in the comparison with before the intervention or between groups. TBRS training can effectively increase exercise capacity, while there are indications that it can alleviate COPD-related dyspnoea and reduce the number of acute exacerbations of COPD. Interestingly, long-term regular TBRS training may reduce oxidative stress associated with COPD to increase exercise capacity.
Low-dose shift- and rotation-invariant diffraction recognition imaging
Authors: Latychevskaia Tatiana , Kohli Alice 
Published: July 2022

AbstractA low-dose imaging technique which uses recognition rather than recording of a full high-resolution image is proposed. A structural hypothesis is verified by probing the object with only a few particles (photons, electrons). Each scattered particle is detected in the far field and its position on the detector is analysed by applying Bayesian statistics. Already a few detected particles are sufficient to confirm a structural hypothesis at a probability exceeding 95%. As an example, the method is demonstrated as an application in optical character recognition, where a hand-written number is recognized from a set of different written numbers. In other provided examples, the structural hypothesis of a single macromolecule is recognized from a diffraction pattern acquired at an extremely low radiation dose, less than one X-ray photon or electron per Å2, thus leaving the macromolecule practically without any radiation damage. The proposed principle of low-dose recognition can be utilized in various applications, ranging from optical character recognition and optical security elements to recognizing a certain protein or its conformation.
Alterations in corneal epithelial dendritic cell in Sjogren’s syndrome dry eye and clinical correlations
Authors: Hao Ran , Ding Yi , Li Xuemin 
Published: July 2022

AbstractWe aimed to investigate the density and morphology of corneal dendritic cells (DCs) in dry eye (DE) patients with or without Sjogren’s syndrome (SS). This study included 28 patients with Sjogren’s syndrome dry eye (SSDE), 33 patients with non-Sjogren’s syndrome dry eye (NSSDE), and 30 age and sex matched healthy volunteers. In vivo confocal microscopy (IVCM) was used to investigate density and morphology (size, dendrites, and field) of DC. Compared with NSSDE and healthy group, SSDE showed significantly higher DC density, larger DC size, more DC dendrites with larger DC field (all P < 0.001). Comparison between NSSDE and healthy group demonstrated that DC density, dendrites and field were significantly higher in NSSDE. However, there was no significant difference in DC size (P = 0.076). DC density and morphological parameters showed significant associations with the systemic severity (salivary gland biopsy and serum antibodies) and ocular surface damage. The corneal epithelium DC density and morphological alterations were obvious in SSDE, which reflected higher level of immune activation and inflammatory response in SS. Marked correlations were found between DC density/morphology and systemic/ocular severity. Dynamic assessment of corneal DC may facilitate to clarify pathogenesis, stratify patient, and tailor treatment in SS patients.
Visceral adiposity is associated with metabolic profiles predictive of type 2 diabetes and myocardial infarction
Authors: Raheem Javeria , Sliz Eeva , Shin Jean , Holmes Michael V. , Pike G. Bruce , Richer Louis , Gaudet Daniel , Paus Tomas , Pausova Zdenka 
Published: July 2022

Abstract
Background
Visceral fat (VF) increases risk for cardiometabolic disease (CMD), the leading cause of morbidity and mortality. Variations in the circulating metabolome predict the risk for CMD but whether or not this is related to VF is unknown. Further, CMD is now also present in adolescents, and the relationships between VF, circulating metabolome, and CMD may vary between adolescents and adults.

Methods
With an aim to add understanding to the metabolic variations in visceral obesity, we tested associations between VF, measured directly with magnetic resonance imaging, and 228 fasting serum metabolomic measures, quantified with nuclear magnetic resonance spectroscopy, in 507 adults (36–65 years) and 938 adolescents (12–18 years). We further utilized data from published studies to estimate similarities between VF and CMD-associated metabolic profiles.

Results
Here we show that VF, independently of body mass index (BMI) or subcutaneous fat, is associated with triglyceride-rich lipoproteins, fatty acids, and inflammation in both adults and adolescents, whereas the associations with amino acids, glucose, and intermediary metabolites are significant in adults only. BMI-adjusted metabolomic profile of VF resembles those predicting type 2 diabetes in adults (R2 = 0.88) and adolescents (R2 = 0.70), and myocardial infarction in adults (R2 = 0.59) and adolescents (R2 = 0.40); this is not the case for ischemic stroke (adults: R2 = 0.05, adolescents: R2 = 0.08).

Conclusions
Visceral adiposity is associated with metabolomic profiles predictive of type 2 diabetes and myocardial infarction even in normal-weight individuals and already in adolescence. Targeting factors contributing to the emergence and maintenance of these profiles might ameliorate their cumulative effects on cardiometabolic health.
Neuronal activity under transcranial radio-frequency stimulation in metal-free rodent brains in-vivo
Authors: Yaghmazadeh Omid , Vöröslakos Mihály , Alon Leeor , Carluccio Giuseppe , Collins Christopher , Sodickson Daniel K. , Buzsáki György 
Published: July 2022

AbstractAs the use of Radio Frequency (RF) technologies increases, the impact of RF radiation on neurological function continues to receive attention. Whether RF radiation can modulate ongoing neuronal activity by non-thermal mechanisms has been debated for decades. However, the interactions between radiated energy and metal-based neural probes during experimentation could impact neural activity, making interpretation of the results difficult. To address this problem, we modified a miniature 1-photon Ca2+ imaging device to record interference-free neural activity and compared the results to those acquired using metal-containing silicon probes. We monitored the neuronal activity of awake rodent-brains under RF energy exposure (at 950 MHz) and in sham control paradigms. Spiking activity was reliably affected by RF energy in metal containing systems. However, we did not observe neuronal responses using metal-free optical recordings at induced local electric field strengths up to 230 V/m. Our results suggest that RF exposure higher than levels that are allowed by regulatory limits in real-life scenarios do not affect neuronal activity.
Early biochemical observations point to nutritional strategies to manage non-alcoholic fatty liver disease
Authors: Calder Philip C. 
Published: July 2022

Abstract
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver disease globally. The first stage of NAFLD is steatosis, the accumulation of triacylglycerols within hepatocytes. Inflammation and oxidative stress both contribute to progression to more severe disease. In 2004 Clinical Science published two papers reporting on fatty acids and oxidative stress markers in the livers of patients with NAFLD; both these papers are highly cited. One paper reported an altered pattern of fatty acids within the livers of patients with NAFLD; there was a lower contribution of polyunsaturated fatty acids (PUFAs) including both n - 6 and n - 3 PUFAs and an altered balance between n - 6 and n - 3 PUFAs in favour of the former. Ratios of precursor PUFAs to their long chain more unsaturated derivatives were altered in NAFLD and were interpreted to indicate a reduced activity of the pathway of synthesis of long chain highly unsaturated PUFAs. The authors interpreted their findings to indicate that a low hepatic content of n - 3 PUFAs has a causal role in NAFLD. The second paper reported lower hepatic antioxidant defences and increased markers of oxidative stress in NAFLD, consistent with a role for oxidative stress in the disease. Many studies have now explored the effect of supplemental n - 3 PUFAs or antioxidants, including vitamin E, in patients with NAFLD with some benefits being reported. There remains much interest in n - 3 PUFAs and antioxidants as preventive and therapeutic strategies in NAFLD and therefore it seems likely that citation of the two papers from 2004 will be sustained.
A selective image encryption scheme using LICC hyperchaotic system
Authors: Wei Chengjing , Li Guodong 
Published: July 2022

AbstractIn this paper, an improved multi‐dimensional hyperchaotic system derived from the logistic map and the ICMIC based on closed‐loop coupling (LICC hyperchaotic system) is proposed and it is used in the design of selective image encryption. The performance analysis shows that the LICC hyperchaotic system with a strong coupling degree has parameters whose value can be set more flexibly and can generate a wider and more uniform distribution of chaotic sequences. Then selective image encryption is proposed. Firstly, an adaptive pseudo‐random sequence generator based on hash function is designed to ensure the difference of sequences used in different encryption steps. Second, a novel bit‐level scrambling is designed to increase the encryption speed. Finally, an efficient rule to select image blocks with weak security is proposed and the second step of the encryption is performed at the selected blocks of the image to ensure security. The encryption performance and security analysis show that the proposed encryption algorithm based on an improved hyperchaotic system is secure enough to resist several types of attacks.
A novel fixed‐time dynamic surface DC/DC SEPIC converter controller loaded by uncertain buck‐based constant power loads
Authors: Sarrafan Neda , Horiyat Navid , Zarei Jafar , Razavi‐Far Roozbeh , Saif Mehrdad , Dragičević Tomislav 
Published: July 2022

AbstractThe stability analysis of the single‐ended primary‐inductor converter DC/DC converters feeding constant power loads (CPLs) is of major importance. The nonlinear behaviour of CPLs and their negative incremental impedance, which impose adverse effects on system damping and stability margins, necessitate developing proper strategies for an efficient implementation framework of DC microgrid. In this paper, a fixed‐time sliding mode disturbance observer is first addressed to provide an estimation of the power flow moving along the uncertain CPLs with time‐varying nature within a fixed time. It not only expedites the estimation rate but also improves the robustness against physical parameter variation. The fixed‐time dynamic surface control law is then developed based on the estimated load power for the duty cycle of the switch such that the entire power grid becomes stable and the desired voltage of the DC bus is tracked within a fixed time irrespective of the initial conditions. A rigorous Lyapunov‐based approach is represented to guarantee the semi‐global fixed‐time uniform ultimate boundedness of the proposed scheme. Finally, in order to verify the proposed methodology's strengths, Model‐in‐the‐Loop real‐time simulations are performed under various operating case studies.
Intelligent energy management of low carbon hybrid energy system with solid oxide fuel cell and accurate battery model
Authors: Chen Tao , Gao Ciwei , Wang Zhengqin , Ming Hao , Song Meng , Yan Xingyu 
Published: July 2022

AbstractIn this study, an intelligent energy management method is introduced to deal with the hydrogen‐dominant hybrid energy system with low carbon consideration. Specially, both the new type fuel cell, solid oxide fuel cell, and chemical battery are subtly modelled to construct a high‐efficient hybrid energy system, in which the thermodynamics feature and accurate battery model characteristics, as well as low carbon effect, are considered. Because the hybrid energy system incorporates various complex dynamic operation features that are hard to capture via conventional operation strategy, an energy management method based on deep reinforcement learning techniques is proposed to guide the intelligent operation with self‐adaptive performance. In the simulation, it is observed that highly efficient use of hydrogen in the hybrid energy system with the aid of chemical battery could achieve good economic benefit, as well as low carbon advantages. Powered by the gas and chemical energy coupling storage effect and state‐of‐the‐art machine learning methods, the proposed intelligent energy management strategy can benefit more renewable energy adoption and guarantee the ultimate environmental friendly low carbon ecosystem in the long‐term future.
Asteroid taxonomy from cluster analysis of spectrometry and albedo
Authors: Mahlke M. , Carry B. , Mattei P.-A. 
Published: July 2022

Context. The classification of the minor bodies of the Solar System based on observables has been continuously developed and iterated over the past 40 yr. While prior iterations followed either the availability of large observational campaigns or new instrumental capabilities opening new observational dimensions, we see the opportunity to improve primarily upon the established methodology.
Aims. We developed an iteration of the asteroid taxonomy which allows the classification of partial and complete observations (i.e. visible, near-infrared, and visible-near-infrared spectrometry) and which reintroduces the visual albedo into the classification observables. The resulting class assignments are given probabilistically, enabling the uncertainty of a classification to be quantified.
Methods. We built the taxonomy based on 2983 observations of 2125 individual asteroids, representing an almost tenfold increase of sample size compared with the previous taxonomy. The asteroid classes are identified in a lower-dimensional representation of the observations using a mixture of common factor analysers model.
Results. We identify 17 classes split into the three complexes C, M, and S, including the new Z-class for extremely-red objects in the main belt. The visual albedo information resolves the spectral degeneracy of the X-complex and establishes the P-class as part of the C-complex. We present a classification tool which computes probabilistic class assignments within this taxonomic scheme from asteroid observations, intrinsically accounting for degeneracies between classes based on the observed wavelength region. The taxonomic classifications of 6038 observations of 4526 individual asteroids are published.
Conclusions. The ability to classify partial observations and the reintroduction of the visual albedo into the classification provide a taxonomy which is well suited for the current and future datasets of asteroid observations, in particular provided by the Gaia, MITHNEOS, NEO Surveyor, and SPHEREx surveys.
Aspects of thermal modeling using digital terrain models
Authors: Gläser P. 
Published: July 2022

Context. Our thermal model is adapted and extended in this study. Specifically the aspect of handling indirect radiation, the solar limb darkening effect, and depth profiles are addressed.
Aims. Our goal is to improve the existing thermal model to handle terrain scattering and re-radiation in an adaptive way. In addition, we aim to change previously fixed and manually chosen discretization of the solar limb darkening effect and depth profile to be adaptive and applicable for various planets and purposes.
Methods. The temperature was modeled based on digital terrain models (DTMs) using data of the Mercury Laser Altimeter (MLA). New implementations to handle terrain scattering and re-radiation were introduced using level-of-detail techniques. The solar disk was discretized into a variable number of rings and the depth profile was introduced as an exponential function for which the number of nodes and the maximum depth can be chosen.
Results. We present results for the ideal window size and degree of level-of-detail for thermal studies of the Hermean north pole. Further we show that the previous discretization of the solar limb darkening effect proved insufficient for Mercury, and we updated the implementation accordingly. Similarly we improved the implementation for the depth profile. For the first time, we derived depth-to-ice, as well as average and maximum temperature maps based on thermal modeling of the complete north polar MLA DTM.
X-ray view of the 2021 outburst of SXP 15.6: Constraints on the binary orbit and magnetic field of the neutron star
Authors: Vasilopoulos G. , Jaisawal G. K. , Maitra C. , Haberl F. , Maggi P. , Karaferias A. S. 
Published: July 2022

Aims.We conducted a spectral and temporal analysis of X-ray data from the Be X-ray binary pulsar SXP 15.6 located in the Small Magellanic Cloud based onNuSTAR,NICER, andSwiftobservations during the 2021 outburst.Methods.We present the broadband X-ray spectra of the system based on simultaneousNuSTARandNICERobservations for the first time. Moreover, we used monitoring data to study the spectral and temporal properties of the system during the outburst.Results.Comparison of the evolution of the 2021 outburst with archival data reveals a consistent pattern of variability, with multiple peaks occurring at time intervals similar to the orbital period of the system (∼36 d). Our spectral analysis indicates that most of the energy is released at high energies above 10 keV, while we found no cyclotron absorption line in the spectrum. Analysing of the spectral evolution during the outburst, we find that the spectrum is softer when brighter, which in turn reveals that the system is probably in the super-critical regime in which the accretion column is formed. This places an upper limit on the magnetic field of the system of about 7 × 1011G. The spin-evolution of the neutron star (NS) during the outburst is consistent with an NS with a low magnetic field (∼5 × 1011G), while there is evident orbital modulation that we modelled, and we derived the orbital parameters. We found the orbit to have a moderate eccentricity of ∼0.3. Our estimates of the magnetic field are consistent with the lack of an electron cyclotron resonance scattering feature in the broadband X-ray spectrum.
Xanthogranulomatous Oophoritis in the Setting of Post-IVF Twin Pregnancy with History of Endometriosis: A Rare Case Report with Review of Literature
Authors: Pendharkar Chinmay Shrikrishna , B.S Sunita , Pendkur Ganesh , Nandagawe Dheeraj J. 
Published: July 2022

AbstractXanthogranulomatous inflammation is an uncommon, nonneoplastic, chronic process in which the affected organ is destroyed by massive cellular infiltration of foamy histiocytes admixed with multinucleated giant cells, plasma cells, fibroblasts, neutrophils, and foci of necrosis. The organs most commonly affected by this entity are kidney and gallbladder. Only a few cases involving the ovary have been reported. The etiology of this entity is unknown, but the associated risk factors are infection, inappropriate antibiotic therapy, use of intrauterine contraceptive device, abnormalities in lipid metabolism, endometriosis, leiomyoma, and recurrent pelvic inflammatory disease. The current case was a 31-year-old female with post-in vitro fertilization (post-IVF) twin pregnancy, who presented with pain in the abdomen, provisionally diagnosed as ovarian mass with suspicion of malignancy. Patient was treated with antibiotics and an elective lower segment cesarean section was planned, due to lower abdominal pain and the presentation of both fetuses being breech. Patient underwent exploratory laparotomy with right oophorectomy and left double-J stenting, in view of left hydronephrosis. Diagnosis of xanthogranulomatous oophoritis was established on histopathological examination. There is only a single case; previously documented from India, in the setting of primary infertility. The present case report stresses that the condition may affect women of any age group and may be encountered in pregnancy, as has been observed in this case. Hence, thinking about this differential diagnosis in the cases presenting with similar complaints, would be of great value to avoid misdiagnosing them.