bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chairside transformation of a removable partial denture to a transitional complete denture to alleviate an impaired stroke patient: A case report
Authors: Papalexopoulos Dimokritos , Samartzi Theodora‐Kalliopi , Sykaras Nikitas , Artopoulou Ioli Ioanna 
Published: October 2022

AbstractBackgroundThe purpose of this clinical report is to present a technique for transformation of an existing removable partial denture (RPD) into a transitional complete denture (CD) for an impaired stroke patient.Case PresentationA 67‐year‐old male who underwent an ischemic stroke 12 months ago presented in the Postgraduate Clinic of the National and Kapodistrian University of Athens, requiring treatment of his remaining teeth and repair of his existing RPD which lacked retention and stability. The treatment plan included placement of amalgam plugs on the remaining teeth which were decoronated due to poor prognosis and modification of the existing RPD to a transitional CD. The procedure included one alginate impression and chairside alteration of the prosthesis with simple means. The new prosthesis managed to improve patient's masticatory ability and reduce the risk for aspiration pneumonia.ConclusionIn the present case report a technique for modifying an existing RPD into a transitional CD for an impaired, stroke patient is described. Reduced treatment time, costs and patient's inconvenience while embracing the benefits provided by the utilization of an existing prosthesis regarding adaptation of the neuromuscular system are among the advantages of the described technique.
Institutional erosion and new strategies: Changing contexts for learning in agriculture in Northern Sweden
Authors: Waldenström Cecilia 
Published: October 2022

AbstractThis article describes the erosion of institutions that support farmers’ learning and the construction of knowledge in agriculture in an area of agricultural decline. It is based on a qualitative study in northern Sweden, exploring farmers’ learning to farm, their peer networks, contacts with advisory services and their sales relationships. As farming is increasingly differentiated, with an intensification of production in some areas and increasing farmland abandonment in others, so are the institutions that support farmers’ learning. Farmers handle this in different ways, and the article indicates that resourceful farmers, dependent on farm income, seek out and create contexts for learning. Others seem increasingly decoupled from advisory institutions and upstream industries, selling their produce in local networks. The article illustrates that the widening gap in agrarian production is related to a differentiation of social and institutional preconditions for the construction of knowledge in farming.
The Arabidopsis TETRATRICOPEPTIDE‐REPEAT THIOREDOXIN‐LIKE (TTL) family members are involved in root system formation via their interaction with cytoskeleton and cell wall remodeling
Authors: Xin Pengfei , Schier Jakub , Šefrnová Yvetta , Kulich Ivan , Dubrovsky Joseph G. , Vielle‐Calzada Jean‐Philippe , Soukup Aleš 
Published: October 2022

SUMMARYLateral roots (LR) are essential components of the plant edaphic interface; contributing to water and nutrient uptake, biotic and abiotic interactions, stress survival, and plant anchorage. We have identified the TETRATRICOPEPTIDE‐REPEAT THIOREDOXIN‐LIKE 3 (TTL3) gene as being related to LR emergence and later development. Loss of function of TTL3 leads to a reduced number of emerged LR due to delayed development of lateral root primordia (LRP). This trait is further enhanced in the triple mutant ttl1ttl3ttl4. TTL3 interacts with microtubules and endomembranes, and is known to participate in the brassinosteroid (BR) signaling pathway. Both ttl3 and ttl1ttl3ttl4 mutants are less sensitive to BR treatment in terms of LR formation and primary root growth. The ability of TTL3 to modulate biophysical properties of the cell wall was established under restrictive conditions of hyperosmotic stress and loss of root growth recovery, which was enhanced in ttl1ttl3ttl4. Timing and spatial distribution of TTL3 expression is consistent with its role in development of LRP before their emergence and subsequent growth of LR. TTL3 emerged as a component of the root system morphogenesis regulatory network.
Network Inference From Local Measurements: Application to Coordination of Groups of Mobile Three-Dimensional Printers
Authors: Tuqan Mohammad , Boldini Alain , Porfiri Maurizio 
Published: October 2022

Abstract
In recent years, three-dimensional (3D) construction printing has emerged as a viable alternative to conventional construction methods. Particularly promising for large scale construction are collective printing systems consisting of multiple mobile 3D printers. However, the design of these systems typically relies on the assumption of continuous communication between the printers, which is unrealistic in dynamically changing construction environments. As a first step toward decentralized collective 3D printing, we explore an active sensing framework allowing individual agents to reconstruct the shape of the structure, toward assessing other agents' progress in the absence of direct communication. In this vein, the shape of the structure is discretized as a 2D lattice embodying its topology, such that the problem is equivalent to the inference of a network. We leverage environmental modifications introduced by each agent through the printing of new layers to track the structure evolution. We demonstrate the validity of a sequential approach based on system identification through numerical simulations. Our work paves the way to decentralized collective 3D construction printing, as well as other applications in collective behavior that rely on the physical medium to transfer information among agents.
Module-Level Thermal Interface Material Degradation in HALT
Authors: Tompkins Joshua , Garcia Alicia Medina , Huitink David , Liao Haitao 
Published: October 2022

Abstract
In this study, thermal interface material (TIM) degradation is driven through highly accelerated life test (HALT) using temperature cycling with a prescribed vibrational acceleration for two commercially available materials having thermal conductivities of 6.0 and 8.5 W/m K. HALT specimens were prepared by applying TIM through a 4-mil stencil over AlSiC baseplates in the shape of those used in Wolfspeed CAS325M12HM2 power electronics modules. Baseplates were mounted onto aluminum carrier blocks with embedded thermocouples to characterize the thermal resistance across the baseplate and TIM layer. Thermal dissipation into the top of the baseplates was provided by a custom heating block, which mimics the size and placement of the die junctions in CAS325 modules, applying power loads of 200, 300, and 400 W. After initial characterization, samples were transferred to the HALT chamber with one set of samples exposed to temperature cycling only (TCO) and the other temperature cycling and vibration (TCV). Both sample sets were cycled between temperature extremes of −40 °C and 180 °C with vibrations applied at a peak acceleration of 3.21 Grms. After hundreds of cycles, samples were reevaluated to assess changes in thermal resistance to provide an accelerated measure of TIM degradation. This allows for reliability prediction of useful lifetime (illustrated in a solar inverter case study herein), as well as to provide a basis for developing an accelerated testing method to related temperature cycling to faster methods of degradation. Such techniques provide a means to develop maintenance schedules for power modules for ensuring sufficient thermal performance over the operating lifetime.
Bubble Size Distribution Dependence on Liquid Viscosity and Gas Flowrate Within a Bubble Column With a Porous Sparger
Authors: Mohagheghian Shahrouz , Ghajar Afshin J. , Elbing Brian R. 
Published: October 2022

Abstract
Bubble size distributions within the homogeneous and heterogeneous regimes were experimentally investigated with varying gas superficial velocity and viscosity. Air was bubbled into aqueous solutions of glycerin (concentrations from 0% to 85%) through a porous stone sparger. A minimum of 2400 bubbles were measured per operating condition. The probability density functions were shown to be near Gaussian (normal) and lognormal for the homogeneous and heterogeneous regimes, respectively. Deviations from these distributions were observed at the bubble size extrema. The skewness and kurtosis were used to determine the operation regime and further analyzed. The homogeneous results showed excellent agreement with a power-law correlation for initial bubble sizes with only slight modifications to the constant and exponent, even though extrapolation over two orders of magnitude was required for the comparison. A dimensionally reasoned scaling law for bubbles in the heterogeneous regime was formed following similar logic to classic work analyzing the breakage of droplets within isotropic turbulence. Once again, the current results were in excellent agreement with slight modifications to the proportionality constant and exponent.
A Probabilistic Model for Forging Flaw Crack Nucleation Processes for Heavy Duty Gas Turbine Rotor Operations
Authors: Radaelli Francesco , Amann Christian , Aydin Ali , Varfolomeev Igor , Gumbsch Peter , Kadau Kai 
Published: October 2022

Abstract
We present a probabilistic model for quantifying the number of load cycles for nucleation of forging flaws—for a 3.5NiCrMoV high strength low alloy rotor steel—into a crack under gas turbine operating conditions. The model correlates low cycle fatigue data, ultrasonic testing indication data, flaw morphology, and type with the nucleation process. This paper is the third of a series of publications presenting this modeling approach progressively. It focuses on the effect of temperature variation on the nucleation life of forging flaws. We quantified the number of cycles to crack nucleation was for specimens that included forging flaws at elevated temperatures. Flaws of different sizes and shapes are effectively described at respective temperature and stress levels by either an ellipsoidal finite element model or an analytical area-based model. A local probabilistic low-cycle fatigue model analyzes the resulting stress distributions accounting for statistical size effects. Via Maximum Likelihood Estimation of these probabilistic low cycle fatigue results, a probabilistic model for crack nucleation of forging flaws is obtained. This proposed probabilistic model is based on experimental data for realistic heavy duty gas turbine rotor temperature and stress conditions. It can be utilized in the energy sector for component life time quantification. Our suggested approach can support component assessment under flexible gas turbines operation conditions driven by increased availability of intermittent renewable energy sources.
Supplemental Material: Topographic development of a compressional mountain range, the western Transverse Ranges of California, USA, resulted from localized uplift along individual structures and regional uplift from deeper shortening
Authors: Onderdonk N. , al. et 
Published: October 2022

<p>Contains PDF and radial plots of luminescence data (Item A), log-log plots of cumulative incision vs age for fluvial terraces (Item B), and profiles of terrace surfaces displaced by faults (Item C)</p>
Factors affecting delay in the presentation of breast cancer symptoms among women in Gaza, occupied Palestinian territory: a cross-sectional survey
Authors: Abo Al-Shiekh Samira S , Alajerami Yasser S , Abushab Khaled M , Najim Ahmed A , AlWaheidi Shaymaa , Davies Elizabeth A 
Published: October 2022

ObjectiveTo identify factors related to women’s delay in presenting with breast cancer symptoms to improve diagnosis in the occupied Palestinian territory (oPt).DesignCross-sectional.SettingTwo government cancer hospitals.ParticipantsA consecutive sample of 130 Palestinian women living in Gaza with newly diagnosed breast cancer were approached in the waiting rooms of cancer hospitals in Gaza between 1 January 2017 and 31 December 2017. 120 women took part and returned the completed questionnaire.Primary and secondary outcome measuresClinical information about breast cancer was collected from hospital cancer records. An interval of 3 months or more between women’s self-discovery of symptoms and their first presentation to a medical provider was considered as a delay.Results94% (122/130) of women attending cancer hospitals in Gaza agreed to take part in the study. Their mean age was 51 years (range: 23–72), 33.6% (31/122) had a family history of breast cancer and 74.5% (41/55) of those whose cancer stage was known had been diagnosed at stage III or IV. Around one-half (62/122) said they had not recognised the seriousness of their breast changes but only 20% (24/122) of women delayed seeking healthcare by 3 months and more. The two only factors associated to late presentation were that the woman considered their symptoms not serious (p<0.001) and lack of pain (p=0.012). Lower socioeconomic status, older age, lower education and negative family history of breast cancer were not statistically associated with women’s delay.ConclusionsWomen’s awareness about the seriousness of breast changes and the critical importance of seeking prompt diagnosis needs to be improved using context-relevant and evidence-based awareness campaigns. This should be accompanied with training of female nurses on promoting early detection and improvement in diagnostic facilities to ensure timely diagnosis of cancer in the oPt.
Tayside Screening For Cardiac Events (TASCFORCE) study: a prospective cardiovascular risk screening study
Authors: Lambert Matthew A , Houston J Graeme , Littleford Roberta , Fitton Catherine A , Struthers Allan , Sullivan Frank , Gandy Stephen , Belch Jill J F 
Published: October 2022

PurposeRisk factor-based models struggle to accurately predict the development of cardiovascular disease (CVD) at the level of the individual. Ways of identifying people with low predicted risk who will develop CVD would allow stratified advice and support informed treatment decisions about the initiation or adjustment of preventive medication, and this is the aim of this prospective cohort study.ParticipantsThe Tayside Screening for Cardiac Events (TASCFORCE) study recruited men and women aged≥40 years, free from known CVD, with a predicted 10-year risk of coronary heart disease<20%. If B-type natriuretic peptide (BNP) was greater than their gender median, participants were offered a whole-body contrast-enhanced MRI (WBCE-MRI) scan (cardiac imaging, whole-body angiography to determine left ventricular parameters, delayed gadolinium enhancement, atheroma burden). Blood, including DNA, was stored for future biomarker assays. Participants are being followed up using electronic record-linkage cardiovascular outcomes.Findings to date4423 (1740, 39.3% men) were recruited. Mean age was 52.3 years with a median BNP of 7.50 ng/L and 15.30 ng/L for men and women, respectively. 602 had a predicted 10-year risk of 10%–19.9%, with the remainder<10%. Age, female sex, ex-smoking status, lower heart rate, higher high-density lipoprotein and lower total cholesterol were independently associated with higher log10 BNP levels. Mean left ventricular mass was 129.2 g and 87.0 g in men and women, respectively.Future plansThe TASCFORCE study is investigating the ability of a screening programme, using BNP and WBCE-MRI, at the time of enrolment, to evaluate prediction of CVD in a population at low/intermediate risk. Blood stored for future biomarker analyses will allow testing/development of novel biomarkers. We believe this could be a new UK Framingham study allowing study for many years to come.Clinical trial registrationISRCTN38976321.
Association between different infection profiles and one-year outcomes in ANCA-associated vasculitis: a retrospective study with monthly infection screening
Authors: Xu Tingting , Chen Zijin , Jiang Mengdi , Ma Hunkun , Jin Kexin , Wang Zhiyu , Wang Chongjian , Xu Jing , Zhang Wen 
Published: October 2022

ObjectivesThis study aimed to explore clinical features of early infection in patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV) and to identify the association between the infection profile of patients with AAV during the first 3 months and 1-year survival.MethodsA total of 415 newly diagnosed patients with AAV in the Department of Nephrology at Shanghai Ruijin Hospital from 2000 to 2018 were included. Four Cox regression models were used to analyse the association based on demographics, comorbidities, laboratory baseline index and therapy parameter. Infection screening was carried out monthly during the first 3 months after diagnosis.ResultsIn all, 377 episodes of infection were identified among 220 patients during the first 3 months. The overall survival after 1 year was 73.0%. Respiratory infection (210 episodes/164 persons) accounted for more than half of infections. Infection was independently associated with 1-year mortality (adjusted HR 2.32, 95% CI 1.27 to 4.23, p=0.006) after adjustment. Respiratory infection (adjusted HR 4.36, 95% CI 2.86 to 8.06, p<0.001), Gram-negative bacterial infection (adjusted HR 1.71, 95% CI 1.01 to 2.91, p=0.047) and fungal infection (adjusted HR 1.77, 95% CI 1.07 to 2.94, p=0.026) was identified as a risk factor for 1-year mortality. Trimethoprim-sulfamethoxazole (TMP-SMX) prophylaxis (adjusted HR 0.55, 95% CI 0.31 to 0.97, p=0.040) was protective for 1-year mortality.ConclusionsInfections, particularly respiratory infections, are a common and important class of complication in patients with AAV and are associated with early mortality. TMP-SMX prophylaxis might be necessary to improve short-term outcome. More consideration of infectious risk and regular infection screening should be given.
Short-time Fourier transform and embedding method for recurrence quantification analysis of EEG time series
Authors: Furman Łukasz , Duch Włodzisław , Minati Ludovico , Tołpa Krzysztof 
Published: October 2022

AbstractElectroencephalography (EEG) allows recording of cortical activity at high temporal resolution. Creating features useful for the analysis of the EEG recording can be challenging. Here we introduce a new method of pre-processing the time-series for the analysis of the resting state and binary task classification using recurrence quantification analysis (RQA) and compare it with the existing state-of-the-art approach based on signal embedding. To reveal patterns that unfold brain dynamics, we present a new pipeline that does not rely on selection of embedding parameters for RQA. Instead of using EEG time-series signals directly, Short-term Fourier transform (STFT) is used to generate new time-series, based on the power spectra from sliding, overlapping windows. Recurrence plots are created in a standard way from embedded EEG signals, and the STFT vectors. The efficiency of RQA features extracted from such plots is compared in classification of EEG segments that correspond to open and closed eye conditions. In contrast to the common approaches to such analysis, no filtering into separate frequency bands was needed. Differences between the two representations of EEG signals are illustrated using histograms of RQA features and UMAP plots. Classification results at the 95.9% level were obtained using selected features for less than 10 electrodes.
A review and tectonic interpretation of the Taconian–Grampian tract between Newfoundland and Scotland: diachronous accretion of an extensive forearc–arc–backarc system to a hyperextended Laurentian margin and subsequent subduction polarity reversal
Authors: van Staal Cees R. , Dewey John F. 
Published: October 2022

Abstract
The Taconian–Grampian tract was characterized by a diachronous collision of a north-facing oceanic arc–forearc terrane and associated backarc basins with an irregular Laurentian margin with hyperextended segments. Hyperextension produced outboard continental terranes, separated by exhumed subcontinental mantle from the inboard margin. The exhumed mantle facilitated continued subduction of the extended margin after it had entered the trench. Enhanced slab-rollback resulted in spreading in lenticular backarc basins, which gradually transitioned along-strike into extensional arcs where rollback was less. Obduction of the oceanic elements onto the irregular Laurentian margin was followed by diachronous slab breakoff and a subduction polarity reversal, such that south- and north-dipping subduction zones locally were coeval along-strike. The polarity flip changed the convergence obliquity from dextral to sinistral and was accompanied by shallowing of the subducting slab near the end of the Middle Ordovician. Strike-slip movements locally juxtaposed segments where tectonic events occurred at different times, producing conflicting relationships. Slab breakoff produced punctuated magmatism, largely driven by mantle-derived melts, and drove and/or enhanced metamorphism in the overlying and enveloping crustal rocks. Boninite was generated episodically over a time span of 32 myr; the oldest Cambrian phase in the Lushs Bight Oceanic Tract (LBOT) and correlatives was associated with subduction initiation.
Downregulation of hsa-miR-135b-5p Inhibits Cell Proliferation, Migration, and Invasion in Colon Adenocarcinoma
Authors: Zhang Yunxin , Zhang Wentao , Xia Wenlong , Xia Junwei , Zhang Haishan 
Published: October 2022

Colon cancer is the most common malignant tumor of the gastrointestinal tract, and approximately 80%–90% of colon cancers are colon adenocarcinomas (COADs). This study aimed to screen key microRNAs (miRNAs) associated with COAD. Differentially expressed (DE) miRNAs were screened between COAD and adjacent cancer samples based on the Gene Expression Omnibus (GEO) and the Cancer Genome Atlas obtained from datasets. The miRNAs of interest were validated using quantitative real-time polymerase chain reaction. Moreover, the effects of hsa-miR-135b-5p on the biological behavior of COAD cells were observed. To obtain the target genes of hsa-miR-135b-5p, transcriptome sequencing of the SW480 cells was performed, followed by protein-protein interaction (PPI) network and hsa-miR-135b-5p-target gene regulatory network construction and prognostic analysis. Downregulation of hsa-miR-135b-5p significantly inhibited SW480 cell proliferation, migration, and invasion and significantly facilitated apoptosis (

P

< 0.05). A total of 3384 DEmRNAs were screened, and enrichment analysis showed that the upregulated mRNAs were enriched in 25 Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways and 326 Gene Ontology Biological Processes (GO-BPs) while the downregulated mRNAs were enriched in 20 KEGG pathways and 276 GO-BPs. A PPI network was then constructed, and H2BC14, H2BC3, and H4C11 had a higher degree. In addition, a total of 352 hsa-miR-135b-5p-gene regulatory relationships were identified. Prognostic analysis showed that FOXN2, NSA2, MYCBP, DIRAS2, DESI1, and RAB33B had prognostic significance (

P

< 0.05). In addition, the validation analysis results showed that FOXN2, NSA2, and DESI1 were significantly expressed between the miR-135b-5p-inhibitor and negative control groups (

P

< 0.05). Therefore, downregulation of hsa-miR-135b-5p inhibits cell proliferation, migration, and invasion in COAD, and carcinogenesis may function by targeting FOXN2, NSA2, MYCBP, DIRAS2, DESI1, and RAB33B.