bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Stress Ulcers Prophylaxis, Sedative and Statin on Ventilator-Associated Pneumonia: A Retrospective Analysis Based on MIMIC Database
Authors: Kong Xuetao , Wu Yaozhou , Wen Bingqin , Meng Dongmei , Wei Li , Yu Pengjiu 
Published: June 2022

Background: The use of MV can easily lead to VAP especially in ICU patients. SUP, sedatives, statin and insulin have been proved to prevent VAP and improve the prognosis of patients. Our aim was to analyze the effects of SUP, sedative, statin, and insulin on patients with MV.Methods: The occurrence of VAP and death in MV patients and VAP patients were explored by multivariate logistic regression and Cox regression to analyze analyses.Results: Totally, 5277 cases who received MV in ICU from MIMIC IV database were included. There were 826 (15.7%) cases in VAP-group and 4451 (84.3%) cases in non-VAP group and there were 1914 (36.3%) cases in hospital mortalities altogether. No protective effect of drugs on VAP was found in MV patients. The risk of death was 1.43 times higher in MV patients taking midazolam than in propofol (aHR = 1.43 95% CI: 1.04,1.97). No protective effect of drugs on death was found in VAP patients.Conclusion: Compared with midazolam, propofol is more recommended as sedation regimen in ICU patients with MV. Further high-quality studies are needed to confirm this finding.
Agreement, Reliability, and Concurrent Validity of an Outdoor, Wearable-Based Walk Ratio Assessment in Healthy Adults and Chronic Stroke Survivors
Authors: Huber Simone K. , Knols Ruud H. , Held Jeremia P. O. , Christen Tom , de Bruin Eling D. 
Published: June 2022

Purpose: The walk ratio (WR)—the step-length/cadence relation—is a promising measure for gait control. GPS-running watches deliver clinically relevant outcomes including the WR. The aim of this study was to determine test-retest agreement, reliability and concurrent validity of an outdoor WR assessment using a GPS-running watch.Methods: Healthy adults and moderate—high functioning stroke survivors (≥6 months), performed the 1 km-outdoor walk twice using a GPS-running watch (Garmin Forerunner 35, GFR35) and a Step Activity Monitor (SAM 3). Global cognition was assessed using the Montreal Cognitive Assessment. Test-retest agreement and reliability were assessed using Bland-Altman plots, standard error of measurement (SEM), intraclass correlation coefficients (ICCs) and smallest detectable changes (SDCs). Concurrent validity was determined by the mean difference (MD), standard error (SE), mean absolute percentage errors (MAPEs) and Spearman’s Rho between GFR35 and SAM3. WR values of the two groups were compared by a Welch’s test. A hierarchical multiple regression was performed with the WR as dependent variable and possible predictors as independent variables.Results: Fifty-one healthy adults [median: 60.0 (47.0, 67.0) years) and 20 stroke survivors [mean: 63.1 (12.4) years, median: 76 (30, 146) months post-stroke] were included. Test-retest agreement and reliability were excellent (SEM% ≤ 2.2, ICCs &gt; 0.9, SDC% ≤ 6.1) and concurrent validity was high (MAPE &lt; 5, ρ &gt; 0.7) for those walking ≥ 1 m/s. Walking &lt; 1 m/s impaired accurate step counting and reduced agreement, reliability, and validity. The WR differed between healthy adults and stroke survivors (t = −2.126, p = 0.045). The hierarchical regression model including stroke and global cognition (Montreal Cognitive Assessment, 0—30) explained 25% of the WR variance (ΔR2 = 0.246, p &lt; 0.001). Stroke had no effect (β = −0.05, p = 0.682), but global cognition was a predictor for an altered WR (β = 0.44, p = 0.001).Discussion: The outdoor WR assessment using the GFR35 showed excellent test-retest agreement, reliability and concurrent validity in healthy adults and chronic stroke survivors walking at least 1 m/s. As the WR seems relevant in chronic stroke, future studies should further investigate this parameter.
Knowledge, Attitude, Practices, and Sources of Information (KAPS) Toward COVID-19 During the Second Wave Pandemic Among University Population in Qatar: A Cross-Sectional Study
Authors: Alkaabi Ibrahim , Abita Magdy , Mahdi Yousif , Ouda Amr , Malki Mohammed Imad 
Published: June 2022

BackgroundThe World Health Organization (WHO) declared COVID-19 as a pandemic on 11 March 2020. Many efforts were performed to contain the virus worldwide. People's knowledge and attitude should be directed toward strict preventive practices to halt the spread of the virus. We aimed to assess the knowledge, attitude, practices, and sources of information (KAPS) used by Qatar University (QU) attendees.MethodsA cross-sectional web-based questionnaire was answered by 500 employees and students in the QU community. It included questions on KAPS toward COVID-19. Information on sociodemographics was collected and analyzed. This study was conducted during the second wave of COVID-18 in the state of Qatar (April–May 2021).ResultsA total of 475 participants aged between 18 and 68 years old consented to complete the survey questionnaire. The study involved 279 (58.7%) non-Qatari nationals and 196 (41.3%) natives, with 254 (53.5%) participants pursuing postgraduate studies and 221 (46.5%) undergraduates. Approximately two-thirds of the sample were employed (64.8%), while one-third were unemployed (35.2%). Knowledge scores on average were 66.4% (M = 5.31, SD = 1.45, and range: 0–8), with only significant differences were noted between nationalities (natives and non-natives) Participants' average score in practices was 69.72% (M = 4.18, SD = 1.7, and range 0–6) with a significant difference in safe COVID-19 practice scores based on the educational level. Adherence with COVID-19 policies and rules were 82% (M = 2.46, SD = 0.7, and range: 0–3) with no differences noted between groups. In addition, the population reported relying on governmental press conferences (76.0%) as their primary source of gaining details concerning COVID-19, followed by social media (64.4%). The least popular resources were information gained from family, relatives, friends, and coworkers (47.4%) and the news channels on TV (46.7%).ConclusionOverall, this study provides insights into Qatar's KAPS toward COVID-19 during the quarantine of the second wave of this pandemic. This study, being the first of its kind to be conducted in the state of Qatar, is expected to help the ministry of public health and the government communication office to establish a suitable measurement of response to the spread of COVID-19 and develop the best practices for any future epidemics that might occur.
Effectiveness and Validation of the Italian Translation of the Low Anterior Resection Syndrome Score in an Italian High-Volume University Hospital
Authors: De Simone Veronica , Litta Francesco , Persiani Roberto , Rizzo Gianluca , Sofo Luigi , Menghi Roberta , Santullo Francesco , Biondi Alberto , Coco Claudio , Sacchetti Franco , Longo Fabio , Attalla El Halabieh Miriam , Moroni Rossana , Ratto Carlo 
Published: June 2022

BackgroundThe low anterior resection syndrome (LARS) score is a validated questionnaire developed in Denmark to measure the severity of bowel dysfunction after low anterior resection. This retrospective study aimed to assess the effectiveness of the LARS score in the Italian language in a population of Italian patients who underwent low anterior resection for rectal cancer. The convergent and discriminative validity and the test-retest reliability of the score were investigated.MethodsA cohort of two hundred and five patients treated with low anterior resection were enrolled in an Italian high-volume university hospital between January 2000 and April 2018. The Italian version of the LARS score (tested twice), as translated from English original version, a single question on quality of life and the EORTC QLQ-C30 questionnaire were submitted to patients.ResultsA high proportion of patients showed a perfect or moderate fit between the LARS score and QoL categories (convergent validity, p &lt; 0.0005). All differences regarding the items of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire – Core 30 (EORTC QLQ-C30) functional scales were statistically significant (p &lt; 0.0005). The LARS score was able to discriminate between groups of patients who received or did not receive preoperative chemoradiotherapy (p &lt; 0.0005) and those who received total or partial mesorectal excision (p &lt; 0.0005). The test-retest reliability was excellent (intraclass correlation coefficient 0.96).ConclusionThe Italian translation of the LARS score is an easy and reliable tool for assessing bowel dysfunction after low anterior resection and its routine use in clinical practice should be recommended.Trial registration number at www.clinicaltrials.gov: NCT04406311.
Is Avoidable Hospitalization Experienced Prior to Infection Associated With COVID-19-Related Deaths?
Authors: Lee Woo-Ri , Yoo Ki-Bong , Lee Gyeong-Min , Koo Jun Hyuk , Kim Li-Hyun 
Published: June 2022

Objectives: This study aimed to determine the effect of the presence or absence of avoidable hospitalization before acquiring coronavirus disease (COVID-19) on COVID-19-related deaths.Methods: This study used the total NHIS-COVID-19 dataset comprising domestic COVID-19 patients, provided by the National Health Insurance Service (NHIS) in South Korea. We conducted logistic regression and double robust estimation (DRE) to confirm the effect of avoidable hospitalization on COVID-19-related deaths.Results: Logistic regression analysis confirmed that the odds ratio (OR) of death due to COVID-19 was high in the group that experienced avoidable hospitalization. DRE analysis showed a higher OR of death due to COVID-19 in the group that experienced avoidable hospitalization compared to the group that did not experience avoidable hospitalization, except in the subgroup aged ≤69 years.Conclusion: The effect of avoidable hospitalization on COVID-19-related deaths was confirmed. Therefore, continued health care, preventive medicine, and public health management are essential for reducing avoidable hospitalizations despite the COVID-19 pandemic. Clinicians need to be informed about the importance of continuous disease management.
Unbounded Energy Collisions inside and outside Black Holes
Authors: Augousti Andy T. , Gusin Pawel , Radosz Andrzej , Ściborski Romuald J. 
Published: June 2022

The possibility of on-horizon collisions of unbounded energy in the case of an extreme Kerr black hole is known as the BSW effect. It is also a widely accepted point of view that the energy collision of two identical particles of mass m near the horizon of a Schwarzschild black hole is limited to a value of 25 m. We show that there are two possible scenarios for unbounded energy collisions both for the exterior and for the interior of spherically symmetric black holes. Similar scenarios are found for axially symmetric black holes. It is shown that divergent (infinite) energy on-(inner)horizon collisions are excluded due to the anisotropic character of the dynamics of black hole interiors.
Patient safety, self-injection, and B12 deficiency: a UK cross-sectional survey
Authors: Tyler Natasha , Hodkinson Alexander , Ahlam Naeem , Giles Sally , Zhou Andrew , Panagioti Maria 
Published: June 2022

BackgroundIndividuals with vitamin B12 deficiency (including pernicious anaemia) often report being ‘let down’ or stigmatised by general practice systems and policy, and choose instead to self-medicate via injection; the association between this and perceptions of safe primary care in this group of people is unknown.AimTo examine the association between self-medication for vitamin B12 deficiency and patient-reported safety in primary care.Design and settingA UK cross-sectional online survey.MethodThe survey consisted of the three components: demographics; the validated Primary Care Patient Measure of Safety; and questions about self-medication for vitamin B12 deficiency. Multivariable logistic regression analyses and thematic synthesis were undertaken.ResultsResponses from 1297 participants indicated 508 (39.2%) self-medicated via injection. Perceived primary care safety was low. Those who self-medicated via injection reported a significantly lower level of patient safety in primary care including adverse patient-related factors (odds ratio 0.82, 95% confidence interval = 0.73 to 0.92), and patients >34 years of age were significantly more likely to self-medicate via injection. Many reported that treatment under the guidance of a clinician was preferable to self-medication, but felt they had no other choice to regain quality of life. Almost half felt that the doctor did not always consider what they wanted for their care.ConclusionTo the authors’ knowledge, this is the largest study to date examining patient safety and vitamin B12 deficiency. It found that four out of 10 patients with B12 deficiency self-medicate via injection. Patients who self-medicated perceived primary care as less safe. Providing patient-centred care and treating these patients with dignity and respect is a policy priority to reduce unsafe health behaviours.
Persepsi Karir, Motivasi Sosial, Dan Pertimbangan Pasar Kerja Terhadap Peminatan Karir sebagai Konsultan Pajak dengan Self Efficacy sebagai Variabel Moderasi
Authors: Lorensia Feren , Pratiwi Hana , Petra Berta Agus 
Published: June 2022

Tujuan dari penelitian ini adalah untuk mengetahui Pengaruh Persepsi Karir, Motivasi Sosial, dan Pertimbangan Pasar Kerja Terhadap Peminatan Karir Sebagai Konsultan dan apakah Self Efficacy mampu memoderasi Pengaruh Persepsi Karir, Motivasi Sosial, dan Pertimbangan Pasar Kerja Terhadap Peminatan Karir Sebagai Konsultan Pajak. Populasi dalam penelitian ini adalah seluruh mahasiswa aktif jurusan Akuntansi yang memilih konsentrasi perpajakan pada Fakultas Ekonomi dan Bisnis Universitas Putra Indonesia YPTK Padang angkatan tahun 2018 yang berjumlah 143 mahasiswa. Teknik pengambilan sampel yang digunakan adalah purposive sampling. Penentuan jumlah sampel yang digunakan dalam penelitian ini menggunakan rumus Slovin. Metode pengumpulan data dengan membagikan kuesioner melalui google form kepada responden mahasiswa/i di Universitas Putra Indonesia YPTK Padang. Metode analisis yang digunakan adalah Analisis Regresi Linear Berganda dan Analisis Regresi Variabel Moderasi (Moderated Regression Analysis) dengan menggunakan program SPSS 22 for windows. Hasil yang didapat secara parsial (uji-t) adalah (1) Motivasi Sosial berpengaruh positif dan signifikan terhadap Peminatan Karir Sebagai Konsultan Pajak, sedangkan (2) Persepsi Karir tidak berpengaruh positif dan signifikan terhadap Peminatan Karir Sebagai Konsultan Pajak, dan (3) Pertimbangan Pasar Kerja tidak berpengaruh positif dan signifikan terhadap Peminatan Karir Sebagai Konsultan Pajak. Namun ketika dimoderasi oleh Self Efficacy tidak terdapat pengaruh antara Persepsi Karir, Motivasi Sosial, dan Pertimbangan Pasar Kerja terhadap Peminatan Karir Sebagai Konsultan Pajak pada mahasiswa jurusan akuntansi konsentrasi perpajakan di Universitas Putra Indonesia “YPTK” Padang.
Project developing and optimizing the composition of wines and alcoholic beverages by blending
Authors: Тимофеев Р.Г. 
Published: June 2022

Сформулированы основные типы подзадач, возникающие в процессе расчета и оптимизации состава и свойств купажа винодельческого продукта. Предложены математические модели, удобные для решения прикладных и теоретических задач по регулированию и оптимизации состава винопродукции методом купажа. Предложены универсальные подходы к решению задач по проектированию и моделированию состава и свойств купажных напитков, реализуемые численными методами на ЭВМ. Результаты работы могут быть использованы для создания прикладных программ по составлению рецептур напитков с заданным составом, а также корректировке и оптимизации состава винодельческой продукции в условиях непостоянства сырьевой базы виноделия.
The main types of subtasks arising in the process of calculating and optimizing the composition and properties of a wine product blend are formulated. Mathematical models, convenient for solving applied and theoretical problems of regulating and optimizing the composition of wine products using the blending method are proposed. Universal approaches to solving problems of project developing and modeling the composition and properties of blended beverages, implemented by numerical methods on computer system, are suggested. The results of the work can be used to create application programs for compiling beverage recipes with a given composition, as well as adjusting and optimizing the composition of wine products in conditions of instability in raw material base of winemaking.
Optimal conditions and generation mechanism of jet atomization for uniform distribution of nano- and micro-droplets
Authors: Matsuura Hiroshi , Furukawa Hiromitsu , Watanabe Yoshinori , Murakami Shin , Ishihara Yuji , Tanikawa Tamio , Hashimoto Hideki 
Published: June 2022

Abstract
This study provides a jet atomization technique to uniformly distribute nano- and micro-particles on the substrate by enclosing them in water droplets to avoid their aggregation. Jet atomization is a two-dimensional uniform spray and is generated using a diaphragm. The ideal jet atomization was achieved when the diaphragm was highly hydrophilic (contact angle 9.8°), and the spring constant was approximately 1.27 N m−1. The several experiments in this study supported the idea that jet atomization was caused by surface wave formed on the water film, rather than by boiling or cavitation of the water. The resonance between the diaphragm and the surface wave was investigated using a simple model. The results of this study can be expected to make fundamental contributions to pharmacy, medicine, and environmental science, where the uniform distribution of fine particles such as drugs, DNAs, and microplastics is required for the analyses of their properties.
APLIKASI PENGELOLAAN E-DOCUMENT SISTEM PENJAMINAN MUTU INTERNAL MENGGUNAKAN METODE USER CENTERED DESIGN
Authors: Harmin Andi , . Rosnani 
Published: June 2022

Unit Penjaminan Mutu Sekolah Tinggi Manajemen Informatika dan Komputer Profesional bertanggungjawab mengelola dokumen Sistem Penjaminan Mutu Internal yang meliputi kebijakan, manual, standar, formulir dan standar operasional prosedur mutu. Anggaran pengelolaan dokumen mutu mulai dari produksi, pembuatan salinan hingga distribusi ke setiap unit kerja mencapai 20 juta rupiah pertahun. Selain aspek anggaran, aspek kegiatan perawatan fisik dokumen juga menjadi perhatian penuh bagi Unit Penjaminan Mutu. Permasalahan ini perlu solusi untuk menekan anggaran dengan memanfaatkan dokumen digital (e-Document) yang memudahkan proses pengelolaan agar pelaksanaan budaya mutu di Sekolah Tinggi Manajemen Informatika dan Komputer Profesional Profesional sesuai dengan visi, misi dan tujuan perguruan tinggi. Penelitian ini menggunakan metode user-centered design untuk pengembangan aplikasi, dimana proyek terpusat pada pengguna yang berkompeten dengan dokumen mutu. Aplikasi e-Document ini dirancang mampu berjalan pada platform web menggunakan personal computer maupun web mobile yang menjadi bagian dari sistem informasi kampus. Hasil dari penelitian ini menjadi solusi bagi penjaminan mutu untuk lebih mudah mengelola dokumen mutu ke seluruh unit kerja dalam lingkup Sekolah Tinggi Manajemen Informatika dan Komputer Profesional Profesional Makassar sehingga efesiensi anggaran pengelolaan dan pengawasan dokumen tidak lagi menjadi kendala bagi penjaminan mutu.
GAME EDUKASI PEMBELAJARAN ANAK USIA DINI BERBASIS ANDROID
Authors: Ardhy Ferly , Adam Gusnaedi , Setiawan Agustinus Eko , Aisyah Anti 
Published: June 2022

Didalam dunia pendidikan pengenalan suatu pembelajaran sangatlah penting, terutamana pada anak usia dini,pembelajaran tidak harus menggunakan buku ataupun penjelasan terhadap anak tersebut salah satu media alternatif bagi pembelajaran anak adalah dengan menggunakan perangkat mobile android yang digunakan untuk membantu tumbuh kembang anak, dan diharapkan dapat meningkatkan motorik anak.dalam study ini, game edukasi 2D yang berjudul game edukasi pembelajaran anak usia dini berbasis android. Yang akan dibuat menggunakan Unity3D untuk pemrograman dasar, dan anroid SDK( Software Development Kit) dan JDK (Java Development kit) yang digunakan untuk merubah sistem aplikasi menjadi APK yang nantinya dapat berjalan diperangkat android.berdasarkan hal tersebut maka hasil yang diperoleh adalah sebuah game edukasi yang dapat dioperasikan di smartphone android yang dapat digunakan sebagai media pembelajaran dan sangat berperan penting serta berdampak positif bagi anak karena bisa memberikan pengetahuan pada anak,sehingga dapat membantu orang tua agar tidak kerepotan untuk menangani proses belajar anak.
SISTEM INFORMASI PENJUALAN ALAT-ALAT PANCING BERBASIS WEB PADA TOKO YOGGI BERSAUDARA DI TALANG PADANG KABUPATEN TANGGAMUS (STUDI KASUS TOKO YOGGI BERSAUDARA)
Authors: Mawarni Rima , Triyanti Dewi , Afriansyah Dodi , Kurniawan Yoggi , Sartika Dwi 
Published: June 2022

Usaha disegala bidang saat ini dipengaruhi dalam sekala besar oleh penggunaan teknoli, terutama pemanfaatan internet. Penggunaan metode transaksi secara online sangat berkembang pesat, bahkan sampai pada beberapa aspek, dan kegiatan yang biasa dilakukan secara manual, sekarang dilakukan dengan menggunakan sistem online. E-commerce semakin diminati karena beberapa keunggulan, seperti biaya operasional yang relatif murah dan kemudahan untuk melakukan manajemen barang yang diperdagangkan serta kemudahan dalam penyusunan laporan yang diperlukan, karena data yang ada adalah data pasti dengan perhitungan yang akurat. Kemudahan yang diberikan melalui layanan e-commerce tentunya dapat memberikan keuntungan pada semua pihak.
Mekanisme promosi dan penjualan alat-alat pancing pada Toko Yoggi Bersaudara saat ini masih banyak dengan cara konvensional yaitu pembeli langsung datang ke tokotersebut. Strategi penjualan seperti ini sangat memungkinkan akan timbulnya masalah dikemudian hari, diantaranya pelanggan/pembeli yang lokasinya berjauhan atau berada di luar kota akan merasa keberatan untuk berbelanja di toko. Pengelolaan manajemen yang masih dilakukan secara manual. Metode pengembangan sistem yang digunakan adalah prototype, dengan alat pengembangan sistem UML,Usecase diagram, class diagram, squen diargam, diagram activity.
Dengan adanya penjualan alat-alat pancing secara online ini diharapkan dapat mempermudah pemilik Toko dalam melakukan pemasaran alat-alat pancing serta membantu dalan membuat laporan pendapatan baik harian ataupun bulanan, sehingga waktu yang digunakan lebih efektif dan efisien.
ظاهرة إتلاف الكتب وتداعياتها المذهبية - دراسة تاريخية في العصر العباسي (132 - 656 هـ / 749 - 1258 م)
Authors: الحدراوي علي 
Published: June 2022

يمثل هذا البحث محاولة أكاديمية لدراسة ظاهرة اتلاف الكتب وتداعياتها المذهبية في العصر العباسي بصفتها الهدف الرئيسي للبحث كواحدة من الظواهر السلبية المنتشرة في العصر العباسي والتي كان لها آثاراً جسيمة على التاريخ الاسلامي والحضارة الاسلامية اذ كلفته فقدان امهات الكتب ونفائسها .
عمد البحث لتقديم لمحة تاريخية عن بدايات هذه الظاهرة وعمقها في التاريخ الاسلامي وبيان ماهية الاتلاف وتعريفه وانواعه والوقوف على دواعي الاتلاف واسبابه كما تطرق البحث لتقديم شواهد تاريخية لاستخدام السلطة العباسية سياسة اتلاف الكتب كسلاح موجه ضد المخالفين مذهبياً وفكرياً امثال الشيعة والزنادقة والمعتزلة كما استعرض البحث موقف العلماء المسلمين من هذه الظاهرة وما كان لها من اثار على الجانب الفكري للإسلام بشكل عام وتوصل البحث الى مجموعة من الاستنتاجات جاءت كخاتمة للبحث.