bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Pentoxifylline on Apoptosis of Kidneyâ€™s Cells Following Acute Methamphetamine Administration in Male Wistar Rats
Authors: Movassaghi Shabnam , Yousefi Oudarji Ali , Sharifi Zahra Nadia 
Published: January 2022

Objective(s):Â Methylenedioxymethamphetamine (MDMA) is a hallucinogenic drug of abuse which is the most popular drugs in the world and has been shown to induce apoptosis in kidney cells. As Pentoxifylline (PTX) increases cAMP and reduces tumor necrosis factor-Î±, the present study aimed to investigate the effects of pentoxifylline on kidney damage induced by acute administration of MDMA in male rat.
Materials & methods: Thirty male rats (250-300 g) were randomly divided into five groups: including control (without any intervention), MDMA group ,the group received 7.5 mg/kg MDMA three times at every two hours for one day ,first experimental group, received 100 mg/kg PTX a week before MDMA administration, second experimental group received 100 mg/kg PTX Just in the time of the third injection of MDMA and the third experimental group received 100 mg/kg PTX followed by one dose of MDMA. Two weeks later, kidneys were removed and prepared for H&E staining, TUNEL and western blot techniques.Â
Results: histopathological studies showed significantly decrease in the kidney cellular damage, in experimental group 1 compared to MDMA group. The number of TUNEL-positive cells was increased significantly in MDMA group. A significant difference was revealed in the mean number of TUNEL-positive cells between the rats treated with PTX before MDMA administration and MDMA group. Expression of active caspase-3 was significantly increased in the MDMA group. While the PTX treatment could significantly decrease when administrated before MDMA injections.
Conclusion: Pentoxifylline can significantly reduce the severity of lesions in the kidney following administration of MDMA.
Imaging of Cerebral Venous and Sinus Thrombosis
Authors: Saadatnia Mohammad 
Published: January 2022

Early and correct diagnosis of cerebral venous and sinus thrombosis (CVST) is necessary for prompt management of this disorder. Neuro-imaging is a crucial part of diagnosis of CVST. I reviewed the findings of non-enhanced computerized tomography (CT), Contrast enhanced CT, CT venography (CTV), different techniques of magnetic resonance imaging (MRI), MR venography, and digital subtraction angiography. I also reviewed the potential pitfalls in image interpretation.
Color Doppler Ultrasound of Carotid and Vertebral Vessels: Anatomy, Technique and Reporting
Authors: Lotfi Mehrzad 
Published: January 2022

Color Doppler study of carotid and vertebral arteries is a non-invasive, reliable and also easily available, cost-effective method for screening and follows up of patients at risk of stroke to differentiate patients need surgery or intervention from whom could be followed by medical management. I reviewed anatomy of cervical arteries and different techniques such as B- mode or gray scale scanning, color flow mapping and spectral analysis for evaluation of both carotid and vertebral arteries.
Cerebral venous sinus thrombosis
Authors: Yadollahikhales Golnaz , Borhani-Haghighi Afshin , Safari Anahid , Wasay Mohammad , C.Edgell Randall 
Published: January 2022

Cerebral venous thrombosis (CVT) is occlusion of dural sinuses and/or cortical veins due to clot formation. It is a potentially life-threatening condition that requires rapid diagnosis and urgent treatment.Cerebral venous thrombosis is more common in females and young people. Pregnancy, postpartum state, contraceptive pills, infection, malignancy, hyper-coagulable state, rheumatological disorders, trauma are among the major etiologies of cerebral venous thrombosis. Headache, focal neurologic deficits and seizure were the most common clinical presentations. Different techniques of unenhanced and contrast enhanced brain computerized tomography(CT scan) and ,magnetic resonance imaging(MRI) are the most helpful ancillary investigations for diagnosis of Cerebral venous thrombosis.Specific treatment of the underlying cause of cerebral venous thrombosis should be considered as the mainstay of the treatment. Anticoagulation with heparin or low molecular weight heparinoids is the most accepted treatment. In acute phase, medical or surgical management to decrease intracranial pressure (ICP) is also recommended. If the patient's clinical condition aggravates despite adequate anticoagulation, thrombolysis or mechanical thrombectomy can be an additive option.
Клініко-демографічні характеристики, ведення пацієнтів із цукровим діабетом 2-го типу та судинними ускладненнями: аналіз української когорти реєстру DISCOVER Global Registry
Authors: Parkhomenko O. M. , Mankovsky B. M. , Vlasenko M. V. , Sokolova L. K. , Lutay Ya. M. , Irkin O. I. , Feiziieva O. L. , Kostetska S. O. , Onachenko L. S. , Vilchynska N. V. , Shkarivska S. V. , Kravchuk N. I. , Chub D. I. , Pertseva N. O. , Malyar K. Yu. , Neporada V. G. , Saienko Ya. A. , Dovhan O. V. 
Published: January 2022

The aim – to describe baseline data of the Ukraine cohort of DISCOVER Global Registry (DGR) with real-world insights on current treatment practices, complications, and associated clinical outcomes in people with type 2 diabetes mellitus (T2DM).Materials and methods. This healthcare provider-led prospective registry involves non‑interventional data collection from adults (aged ≥ 18 years) with T2DM receiving standard medical care as part of routine clinical practice per their treating physician’s discretion. Results and discussion. The initial data of 353 people with T2DM, who were included in the Ukrainian cohort of the DGR Register, were analyzed. The mean (±standard deviation) age of the study population was 58.85±10.02 years with female predominance (64 % [n=226]). The mean T2DM duration was 10.27±12.15 years with a mean glycated hemoglobin (HbA1c) level of 8.62±1.89 %. Only one-fifth (20.5 %, n=59) of the patients had glycemic control (HbA1c < 7.0 %). Among those with any complication, 73.8 % had microvascular and 79.3 % had cardiovascular complications. Retinopathy and heart failure were the most common microvascular and cardiovascular complications, respectively. Overall, 88 % of the patients were taking any antidiabetic therapy; of these, 27.3 % received insulin (monotherapy: n=28; combination therapy: n=57). As oral antidiabetic drugs (OAD), 32.2 % and 12.9 % received metformin and sulphonylurea monotherapies, respectively; minor proportions received newer OAD monotherapy (sodium-glucose co-transporter-2 inhibitors [4.8 %] and dipeptidyl peptidase-4 inhibitor [1 %]).Conclusions. Baseline data from the Ukraine cohort of DGR reveals poor glycemic control, with a higher mean HbA1c and proportion of patients with micro- and cardiovascular complications than that of the global cohort. The landscape of therapeutic agents displayed marked diversities in the management strategies. Robust real-world data from the DGR can help understand the gaps in care of T2DM patients and lights the need of the formulation of region-specific holistic therapeutic strategies to optimize glycemic control and improving clinical patients’ outcomes.
Показники лейкоцитарної та тромбоцитарної ланки крові в динаміці госпітального періоду у хворих з гострим інфарктом міокарда: можливість використання для оцінювання ризику розвитку віддалених ускладнень
Authors: Parkhomenko O. M. , Shumakov V. O. , Talayeva T. V. , Tretyak I. V. , Dovhan O. V. 
Published: January 2022

The aim – to create a new method of assessing the development of long-term complications in STEMI patients by studying blood cell composition and its adaptation to practical application in general clinical practice.Materials and methods. The study was involved 148 patients with acute myocardial infarction (AMI) who was admitted from January 2014 to June 2020 to the intensive care unit. Some patients were evaluated retrospectively and were in group 1 (n=92). Group 2 – 56 patients, who were studied prospectively. The groups of patients did not differ in clinical and anamnestic characteristics and treatment. The study provided an annual observation period. The endpoint in group 1 was: death, stroke, exacerbation of coronary heart disease – including the need for revascularization, the developement or decompensation for heart failure, which led to hospitalization (in addition, group 2 was analyzed for onset of cardiac death).Results and discussion. There complex indicators were built, based on the analysis of the clinical profile and dynamics of laboratory parameters in patients with the onset of the endpoint – a modified leukocyte index (mLI), which contains the values ​​of the number and percentage of granulocytes, lymphocytes and monocytes on days 1, 3 and 10 of STEMI and leukocyte-platelet index (mLPI), which additionally includes indicators of platelet inhomogeneity in size (PDWc and P-LCR). These indices with their limit values ​​(mLI > 140 units and mLPI > 242 units) were more informative in predicting distant cardiovascular events than other laboratory markers (including neutrophil-leukocyte ratio, NLR). In a prospective study branch (group 2), the mLI and mLPI indicators also turned out to be more informative than other markers (in particular, the NLR indicator) in determining the propensity to occur as a combined endpoint (area under the curve 0.71 for both; p<0.0001), so and death (areas under the curve 0.78 and 0.84, respectively; p<0.0001). Based on the data obtained, a computer algorithm has been created that simplifies the risk assessment in AMI patients using the developed indicators.Conclusions. Created leukocyte and leukocyte-platelet indices are highly informative in predicting the risk of complications in patients within a year after AMI.
The Partition Dimension of a Path Graph
Authors: Ramdhani Vivi , Rahmi Fathur 
Published: January 2022

Resolving partition is part of graph theory. This article, explains about resolving partition of the path graph, with. Given a connected graph and is a subset of writen . Suppose there is , then the distance between and is denoted in the form . There is an ordered set of -partitions of, writen then the representation of with respect tois the The set of partitions ofis called a resolving partition if the representation of each to is different. The minimum cardinality of the solving-partition to is called the partition dimension of G which is denoted by . Before getting the partition dimension of a path graph, the first step is to look for resolving partition of the graph. Some resolving partitions of path graph, with , and are obtained. Then, the partition dimension of the path graph which is the minimum cardinality of resolving partition, namely pd (Pn)=2Resolving partition is part of graph theory. This article, explains about resolving partition of the path graph, with. Given a connected graph and is a subset of writen . Suppose there is , then the distance between and is denoted in the form . There is an ordered set of -partitions of, writen then the representation of with respect tois the The set of partitions ofis called a resolving partition if the representation of each to is different. The minimum cardinality of the solving-partition to is called the partition dimension of G which is denoted by . Before getting the partition dimension of a path graph, the first step is to look for resolving partition of the graph. Some resolving partitionsof path graph, with , and are obtained. Then, the partition dimension of the path graph which is the minimum cardinality of resolving partition, namely.
Cassia leptophylla, Gold Medallion Tree
Authors: Andreu Michael G. , Friedman Melissa H. , Northrop Robert J. 
Published: January 2022

Cassia leptophylla, Gold Medallion Tree (FOR295/FR363)
The gold medallion tree is planted primarily as a shade tree or as a decorative specimen for the yard or street. Many people like this tree because of its fast growth rate and showy, bright yellow clusters of flowers that bloom in the summer months. This tree loses its leaves for a very short period each year, but leaves are quickly replaced. Pruning the tree to one main leading stem from which major branches are attached can help increase its strength and sturdiness against strong wind events. The golden medallion tree is also naturally pest resistant, and as long as it is grown in areas where the temperature does not drop below freezing, it is an easy tree to care for. This 2-page fact sheet was written by Michael G. Andreu, Melissa H. Friedman, and Robert J. Northrop, and published by the UF Department of School of Forest Resources and Conservation, July 2012.
http://edis.ifas.ufl.edu/fr363
Zebra Longwing, Heliconius charitonia (Linnaeus) (Insecta: Lepidoptera: Nymphalidae)
Authors: Daniels Jaret C. 
Published: January 2022

EENY-428, a 3-page illustrated fact sheet by Jaret C. Daniels, is part of the Featured Creatures collection. It describes this neotropical butterfly with elongated wings and bold yellow stripes that is the state butterfly of Florida — it’s distribution, description, life cycle, and hosts. Includes references. Published by the UF Department of Entomology and Nematology, February 2009.

EENY 428/IN805: Zebra Longwing, Heliconius charithonia (Linnaeus) (Insecta: Lepidoptera: Nymphalidae) (ufl.edu)
Development of Bahiagrass Fertilization Recommendations: 1990-2008
Authors: Hanlon Edward A. , Mylavarapu Rao , Mackowiak Cheryl L. , Silveira Maria L. 
Published: January 2022

Revised! SL-237, a 15-page fact sheet by E.A. Hanlon, Rao Mylavarapu, C.L. Mackowiak, and M.L. Silveira, records changes in UF/IFAS’ bahiagrass fertilization and liming recommendations from 1990 through 2008 and summarizes efforts of the various work groups and committees. Includes references. Published by the UF Department of Soil and Water Science, January 2006. Revised August 2008 and April 2009.
SL-237/SS456: Development of Bahiagrass Fertilization Recommendations: 1990–2008 (ufl.edu)
BEDSIDE LAPAROSCOPY AS DIAGNOSTIC TOOL REVIEW OF ABDOMINAL PATHOLOGIES IN CRITICALLY ILL PATIENTS: REVIEW
Authors: Coco Danilo , Leanza Silvana 
Published: January 2022

Introduction: The diagnosis of abdominal pathologies in critically ill patients is often difficult because of inconclusive laboratory tests or imaging results, or the inability to safely transfer a patient to the radiology room. These causes give a delayed diagnosis of abdominal pathology in the intensive care unit (ICU) and increase rate of morbidity and mortality. The aim of this retrospective study is to evaluate the safety and diagnostic accuracy of bedside diagnostic laparoscopy in the identification of intra-abdominal pathology in critically ill patients.

Aim: The aim of this retrospective study is to evaluate the safety and diagnostic accuracy of bedside diagnostic laparoscopy in the identification of intra-abdominal pathology in critically ill patients.

Materials and Methods: A literature research was carried out including PubMed, Medline, Embase, Cochrane and Google Scholar databases to identify articles reporting on importance of diagnostic accuracy of bedside diagnostic laparoscopy in the identification of intra-abdominal pathology in critically ill patients.

Conclusions: Bedside diagnostic laparoscopy represents a safe and accurate technique for diagnosing intraabdominal pathology in an ICU setting and should be taken into consideration when patient transfer to radiology or the operating room is considered unsafe or when routine radiological examinations are not conclusive enough to reach a definite diagnosis.

Keywords:
Bedside laparoscopy, critically ill patients, ultrasonography (US), computed tomography (CT) , emergency surgery
Classification of color features in butterflies using the Support Vector Machine (SVM)
Authors: Dhian Satria Yudha Kartika  , Hendra Maulana  
Published: January 2022

Research in digital images is expanding widely and includes several sectors. One sector currently being carried out research is in insects; specifically, butterflies are used as a dataset. A total of 890 types of butterflies divided into ten classes were used as a dataset and classified based on color. Ten types of butterflies include Danaus plexippus, Heliconius charitonius, Heliconius erato, Junonia coenia, Lycaena phlaeas, Nymphalis antiopa, Papilio cresphontes, Pieris rapae, Vanessa atalanta, Vanessa cardui. The process of extracting color features on butterfly wings uses the RGB method to become HSV color space with color quantization (CQ). The purpose of adding CQ is that the computation process is carried out faster without reducing the image's information. In the color feature extraction process, the image is converted into 3-pixel sizes and normalized. The process of normalizing the dataset has the aim that the value ranges in the dataset have the same value. The 890 butterfly dataset was classified using the Support Vector Machine (SVM) method. Based on this research process, the accuracy of the 256x160 pixel size is 72%, the 420x315 pixel is 75%, and the 768x576 pixel is 75%. The test results on a system with a 768x576 pixel get the highest results with a precision value of 74.6%, a recall of 72%, and an f-measure of 73.2%
Keywords—image processing; classification; butterflies; color features; features extraction
KETERPISAHAN ANAK DARI ORANGTUA ATAU PENGASUHNYA PADA MASA PANDEMI COVID-19
Authors: Subardhini Meiti 
Published: January 2022

Â Tulisan ini merupakan kajian literatur yang bertujuan untuk menganalisis fenomena. keterpisahan anak dari orangtua atau pengasuhnya pada masa pandemi COVID-19. Analisis dalam tulisan ini dilakukan melalui kajian pustaka. Pembahasan dalam tulisan ini dimulai dengan mendiskusikan definisi keterpisahan serta gambaran kasus keterpisahan anak pada masa pandemi COVID-19. Defenisi keterpisahan diambil dari Child Protection Working GuidingÂ Principles. Sedangkan gambaran kasus yang diangkat adalah kejadian di Jawa Barat dan DKI Jakarta. Selanjutnya diskusi dipusatkan pada pembahasan masalah psikososial yang dirasakan anak akibat keterpisahan diantaranya :Â sedih, cemas , stress, trauma dan kehilangan. Pembahasan dalam artikel ini ditutup dengan mendiskusikan cara mengatasi anak yang mengalami keterpisahan/kehilangan/ penderitaan yang mengacu pada pedoman umum perlindungan anak penanganan Covid-19. Penulis menyarankan beberapa cara yang dapat dilakukan untuk mencegah dampak keterpisahan anak dengan orang tua pada masa pandemi Covid-19 yaitu belajar mengungkapkan perasaan, jangan biasakan memendam amarah, belajar dari kondisi orang lain.
Antifibrotics and Antioxidants of Chlorogenic Acid Inhibits Toll- Like Receptors-4 as Liver Fibrotic Marker
Authors: Naibey Rosdiana , Wasityastuti Widya , Anggorowati Nungki , Arfian Nur 
Published: January 2022

Introduction: Chlorogenic Acid (CGA) is an antifibrotic and antioxidant for fibrotic tissues. These double roles be able to inhibit or fibrotic tissues chains because of internal and external issues. For example, virus, bacteria or other pathogens and also by drugs, alcohol, cigarettes, etc. as external factor that affect quality of body tissues. Toll-Like Receptor-4 (TLR-4) as a marker fibrotic tissues. It is a key for researcher could be find out by expression performance. The aim of this study is to reveal the CGA as a candidate of antifibrotic & antioxidant in liver fibrosis that induced by CCL4.
Methods: This is a pure experimental research with a simple experimental design or post-test only control group design. The total 29 mices of 2.5-month-old male Swiss mices with weigh 35-40 gram divided into 6 group: 3 groups of controls (injected by natrium chloride, CGA, and CCL4) and 3 groups of treated (injected by CGA doses 42 mg/kg, 63 mg/kg or 84 mg/kg). Liver organ was used to examine the expression of TLR-4 by rt-PCR. This research revealed that expression of TLR-4 lower than the CCL4 control group (respectively, p=0.042; p=0.005; p=0.006; and p=0.001). Higher dose of CGA showed greater ability as anti-fibrotic through inhibit the expression of TLR-4. Some research found the expression of TLR-4 has been decreased by treatment of Clorogenic Acid (CGA).
Conclusion: To sum up, CGA has double roles to repair liver fibrotic tissues. The greater doses of CGA, the stronger inhibition of TLR-4 expression.
On Exports and Economic Growth: Revisiting Export-Led Growth Hypothesis Including North-South Divide
Authors: Sharma Suraj 
Published: January 2022

Objective: The purpose of the present study is to revisit the export-led growth hypothesis in the wake of globalization. This will help in trade policy decisions and make it possible to standpoint whether the export promotion is a good idea to accelerate economic growth. Design: The ELG hypothesis is examined for 107 countries through panel data analysis using cointegration and panel regression tests from 1990 to 2018. The study finds strong support for the long-run relationship between exports and gross domestic product and the export-led growth hypothesis in a two-variable regression framework. Findings: It is evident from the long-run coefficient of dynamic ordinary least squared that a 1.0 percent increase in real exports increases the real gross domestic product by 0.53 percent. The long-run coefficient of real exports for the Global South (0.55) is found higher than that of the Global North (0.51), which indicates that in the wave of globalization, the evidence of export-led growth hypothesis is stronger for comparatively poor Global South than the richer Global North. Practical Implications: The results indicate implications for export promotion policy in the Global South countries to accelerate economic growth and increase real gross domestic product. Originality: The study is the first to explore the ELG hypothesis using a big pool of 107 countries, including the global north-south divide.
Pengaruh Pengungkapan Tanggung Jawab Sosial Perusahaan, Kepemilikan Keluarga, dan Tata Kelola Perusahaan Terhadap Penghindaran Pajak
Authors: Krisyadi Robby , Anita Anita 
Published: January 2022

Perpajakan adalah hal penting yang dapat menambah pendapatan negara tetapi mengurangi pendapatan perusahaan atau pajak. Oleh karena itu, penghindaran pajak dilakukan oleh manajemen perusahaan untuk memaksimalkan pendapatan perusahaan mereka. Penelitian ini dilakukan atas dasar untuk memeriksa efek dari pengungkapan tanggung jawab sosial perusahaan, kepemilikan keluarga, dan tata kelola perusahaan pada penghindaran pajak. Rasio penghindaran pajak perusahaan dalam penelitian ini diproksi dengan Effective Tax Rate (ETR) dengan membagi jumlah beban pajak dengan pendapatan sebelum pajak. Pengungkapan tanggung jawab sosial perusahaan di proksi dengan indeks GRI dengan jumlah indikator 91 item pengungkapan, kepemilikan keluarga diproksi dengan persentase atas kepemilikan keluarga dalam satu perusahaan dan tata kelola perusahaan diproksi dengan indikator GG sebesar 15 item. 136 perusahaan di Bursa Efek Indonesia (BEI) periode 2016-2020 dipilih sebagai sampel penelitian memakai teknik purposive sampling. data yang digunakan dalam analisis ini adalah data panel yang diproses menggunakan SPSS dan Eviews. SPSS digunakan untuk mendeteksi data outlier yang kemudian akan diregresi menggunakan Eviews. Hasil uji menunjukkan kepemilikan keluarga dan pengungkapan tanggung jawab sosial perusahaan memiliki efek signifikan dan positif pada penghindaran pajak sementara variabel tata kelola perusahaan tidak punya efek pada penghindaran pajak.

Kata kunci: Tata Kelola Perusahaan, Pengungkapan Tanggung Jawab Sosial Perusahaan, Kepemilikan Keluarga, Penghindaran Pajak