bluuebunny/crossref_metadata_2025_split huggingface dataset:
Significance of systolic-phase imaging on full-phase ECG-gated CT angiography to detect intimal tears in aortic dissection
Authors: Yanagaki Satoru , Masuda Atsuro , Ota Hideki , Kojima Masatoshi , Hattori Takashi , Mihara Wahei , Takase Kei , Ueda Takuya 
Published: May 2022

AbstractPurposeFor patients with aortic dissection (AD) and intramural hematoma (IMH), the optimal cardiac phase to detect intimal tears (IT) and ulcer-like projections (ULP) on retrospective electrocardiogram (ECG)-gated computed tomography angiography (CTA) remains unclear. The purpose of this study was to compare the accuracy of retrospective ECG-gated CTA for detecting IT in AD and ULP in IMH between each cardiac phase.Materials and methodsA total of 75 consecutive patients with AD and IMH of the thoracic aorta were enrolled in this single-center retrospective study. The diagnostic performance to detect IT and ULP in the thoracic aortic regions (including the ascending aorta, aortic arch, and proximal and distal descending aorta) was compared in each cardiac phase on retrospective ECG-gated CTA.ResultsIn the systolic phase (20%), the accuracy, sensitivity, and specificity to detect IT in AD was 64% (95% confidence interval [CI] 56–72%), 69% (95%CI 60–78%), and 25% (95%CI 3.3–45%), respectively. In the diastolic phase (70%), the accuracy, sensitivity, and specificity to detect IT in AD was 52% (95%CI 43–60%), 52% (95%CI 42–61%), and 50% (95%CI 25–75%), respectively. The accuracy to detect IT in AD on ECG-gated CTA was significantly higher in the systolic phase than that in the diastolic phase (P = 0.025). However, there were no differences in the accuracy (83%; 95%CI 78–89%), sensitivity (71%; 95%CI 62–80%), or specificity (100%; 95%CI 100%) to detect ULP in IMH between the cardiac cycle phases.ConclusionAlthough it is currently recommended for routine diagnosis of AD and IMH, single-diastolic-phase ECG-gated CTA has risk to miss some IT in AD that are detectable in the systolic phase on full-phase ECG-gated CTA. This information is critical for determining the optimal treatment strategy for AD.
Mental health literacy in children and adolescents in low- and middle-income countries: a mixed studies systematic review and narrative synthesis
Authors: Renwick Laoise , Pedley Rebecca , Johnson Isobel , Bell Vicky , Lovell Karina , Bee Penny , Brooks Helen 
Published: May 2022

AbstractMental illnesses are the leading cause of disease burden among children and young people (CYP) globally. Low- and middle-income countries (LMIC) are disproportionately affected. Enhancing mental health literacy (MHL) is one way to combat low levels of help-seeking and effective treatment receipt. We aimed to synthesis evidence about knowledge, beliefs and attitudes of CYP in LMICs about mental illnesses, their treatments and outcomes, evaluating factors that can enhance or impede help-seeking to inform context-specific and developmentally appropriate understandings of MHL. Eight bibliographic databases were searched from inception to July 2020: PsycInfo, EMBASE, Medline (OVID), Scopus, ASSIA (ProQuest), SSCI, SCI (Web of Science) CINAHL PLUS, Social Sciences full text (EBSCO). 58 papers (41 quantitative, 13 qualitative, 4 mixed methods) representing 52 separate studies comprising 36,429 participants with a mean age of 15.3 [10.4–17.4], were appraised and synthesized using narrative synthesis methods. Low levels of recognition and knowledge about mental health problems and illnesses, pervasive levels of stigma and low confidence in professional healthcare services, even when considered a valid treatment option were dominant themes. CYP cited the value of traditional healers and social networks for seeking help. Several important areas were under-researched including the link between specific stigma types and active help-seeking and research is needed to understand more fully the interplay between knowledge, beliefs and attitudes across varied cultural settings. Greater exploration of social networks and the value of collaboration with traditional healers is consistent with promising, yet understudied, areas of community-based MHL interventions combining education and social contact.
The value of intraoperative MRI for resection of functional pituitary adenomas—a critical assessment of a consecutive single-center series of 114 cases
Authors: Scherer Moritz , Zerweck Paul , Becker Daniela , Kihm Lars , Jesser Jessica , Beynon Christopher , Unterberg Andreas 
Published: May 2022

Abstract
This series sought to evaluate the role of intraoperative MRI (iMRI) for resection of functional pituitary adenomas (FPAs). We retrospectively reviewed clinical data of 114 consecutive FPAs with excessive hormone secretion treated with transsphenoidal surgery and iMRI during 01/2010–12/2017. We focused on iMRI findings, extend of resection and postoperative hormonal remission. Variables of incomplete resections and persistent hormone excess were evaluated by binary regression. Patients with FPAs presented with hypercortisolism (n = 23, 20%), acromegaly (n = 56, 49%), and as prolactinomas (n = 35, 31%) resistant to medical treatment. Preoperative MRI showed 81 macroadenomas (71%) and optic system involvement in 41 cases (36%). IMRI was suggestive for residual tumor in 51 cases (45%). Re-inspection of the cavity cleared equivocal findings in 16 cases (14%). Additional tumor was removed in 22 cases (19%). Complete resection was achieved in 95 cases (83%). Postoperative morbidity was low (1.7% revision surgeries, 0.8% permanent diabetes insipidus). Overall hormonal remission-rate was 59% (hypercortisolism 78%, acromegaly 52%, prolactinoma 57%). Supra- and parasellar invasion and preoperative visual impairment were significant predictors for incomplete resections despite use of iMRI. Risk for persistent hormone excess was increased sevenfold after incomplete resections. IMRI enabled reliable identification of tumor remnants during surgery and triggered further resection in a considerable proportion of cases. Nevertheless, tumor size and invasiveness set persistent boundaries to the completeness of resections. The low rate of surgical complications could point at a less invasive iMRI-guided surgical approach while achieving a complete tumor resection was a crucial determinant for hormonal outcome.
Impact of biogas digestates on soil microbiota in agriculture: a review
Authors: Karimi Battle , Sadet-Bourgeteau Sophie , Cannavacciuolo Mario , Chauvin Camille , Flamin Cyril , Haumont Adeline , Jean-Baptiste Vincent , Reibel Aurélie , Vrignaud Grégory , Ranjard Lionel 
Published: May 2022

AbstractThe global production of biogas has increased threefold during the last decade to partly replace fossil fuels, yet biogas production by anaerobic digestion generates substantial amounts of by-products named digestates. These biogas digestates can be recycled in soils to fertilize crops and to sequester carbon. Nonetheless, the impact of digestates on the soil biological is actually poorly known. Here, we reviewed the impact of digestates published in 56 articles reporting 23 microbial parameters. Half of the articles show neutral effects of biogas digestates and 7% showed negative effects. 25% of the articles show more stimulation of the soil microbial quality by biogas digestates, whereas 17% of the articles show less stimulation, compared to other organic fertilizers.
QTL mapping under salt stress in rice using a Kalarata–Azucena population
Authors: de Ocampo Marjorie P. , Ho Viet The , Thomson Michael J. , Mitsuya Shiro , Yamauchi Akira , Ismail Abdelbagi M. 
Published: May 2022

AbstractSalt stress is a major constraint across large rice production areas in Asia, because of the high sensitivity of modern rice varieties. To identify quantitative trait loci (QTL) associated with salt tolerance in rice, we developed an F2 population from a cross between the salt-tolerant landrace, Kalarata, and the salt-sensitive parent, Azucena. F3 families from this population were screened and scored for salt tolerance using IRRI’s Standard evaluation system (SES). Growth, biomass, Na+ and K+ concentrations in leaf tissues, and chlorophyll concentration were determined. A genetic linkage map was constructed with 151 SSRs and InDel markers, which cover 1463 cM with an average distance of 9.69 cM between loci. A total of 13 QTL were identified using Composite Interval Mapping for 16 traits. Several novel QTL were identified in this study, the largest is for root sodium concentration (LOD = 11.0, R2 = 25.0) on chromosome 3, which also co-localize with a QTL for SES. Several QTL on the short arm of chromosome 1 coincide with the Saltol locus identified before. The novel QTL identified in this study constitute future targets for molecular breeding, to combine them with other QTL identified before, for higher tolerance and stable performance of rice varieties in salt affected soils.
Dwarfing gene Rht24 does not affect Fusarium head blight resistance in a large European winter wheat diversity panel
Authors: Miedaner Thomas , Lenhardt Melissa , Grehl Janosch , Gruner Paul , Koch Silvia 
Published: May 2022

AbstractReduced height (Rht) genes are widely used in modern wheat breeding although some confer higher susceptibility to Fusarium head blight (FHB) caused by F. graminearum and other species. Our objective was to test whether the recently identified Rht24b dwarfing allele has a neutral effect on FHB response as reported previously from a single mapping population when unrelated winter wheat cultivars were analyzed. We artificially infected a panel of 420 cultivars divided into four genotypic groups (Rht24a + Rht-D1a, Rht24b + Rht-D1a, Rht24a + Rht-D1b, Rht24b + Rht-D1b) with Fusarium culmorum in five location-year combinations. High and significant (P ≤ 0.001) genetic variance for FHB severity and plant height (PH) was found in the entire panel as well as within the four Rht groups and both traits showed high entry-mean heritabilities of 0.92 and 0.98, respectively. Rht24b had no significant effect on FHB severity whereas Rht-D1b increased FHB susceptibility by 37%. The 29 most resistant cultivars either had the tallness alleles of the above mentioned Rht-D1 gene or Rht24b alone. The Rht24b + Rht-D1b combination had no significantly higher FHB severity than Rht-D1b alone. However, Rht24b reduced average PH only by 6.8 cm, whereas Rht-D1b conferred a reduction of 13.6 cm. For breeding short, FHB-resistant germplasm the neutral Rht24 gene must be complemented by further QTL or other FHB-neutral Rht genes.
Female preference for super-sized male ornaments and its implications for the evolution of ornament allometry
Authors: Summers Thomas C. , Ord Terry J. 
Published: May 2022

AbstractIt has been argued that disproportionately larger ornaments in bigger males—positive allometry—is the outcome of sexual selection operating on the size of condition dependent traits. We reviewed the literature and found a general lack of empirical testing of the assumed link between female preferences for large ornaments and a pattern of positive allometry in male ornamentation. We subsequently conducted a manipulative experiment by leveraging the unusual terrestrial fish, Alticus sp. cf. simplicirrus, on the island of Rarotonga. Males in this species present a prominent head crest to females during courtship, and the size of this head crest in the genus more broadly exhibits the classic pattern of positive allometry. We created realistic male models standardized in body size but differing in head crest size based on the most extreme allometric scaling recorded for the genus. This included a crest size well outside the observed range for the study population (super-sized). The stimuli were presented to free-living females in a manner that mimicked the spatial distribution of courting males. Females directed greater attention to the male stimulus that exhibited the super-sized crest, with little difference in attention direct to other size treatments. These data appear to be the only experimental evidence from the wild of a female preference function that has been implicitly assumed to drive selection that results in the evolution of positive allometry in male ornamentation.
Projected future changes in the contribution of Indo-Pacific sea surface height variability to the Indonesian throughflow
Authors: Shilimkar Vivek , Abe Hiroto , Roxy Mathew Koll , Tanimoto Youichi 
Published: May 2022

AbstractThe Indonesian throughflow (ITF) transports a significant amount of warm freshwater from the Pacific to the Indian Ocean, making it critical to the global climate system. This study examines decadal ITF variations using ocean reanalysis data as well as climate model simulations from the Coupled Model Inter-comparison Project Phase 5 (CMIP5). While the observed annual cycle of ITF transport is known to be correlated with the annual cycle of sea surface height (SSH) difference between the Pacific and Indian Oceans, ocean reanalysis data (1959–2015) show that the Pacific Ocean SSH variability controls more than 85% of ITF variation on decadal timescales. In contrast, the Indian Ocean SSH variability contributes less than 15%. While those observed contributions are mostly reproduced in the CMIP5 historical simulations, an analysis of future climate projections shows a 25–30% increase in the Indian Ocean SSH variability to decadal ITF variations and a corresponding decrease in the Pacific contribution. These projected changes in the Indian Ocean SSH variability are associated with a 23% increase in the amplitudes of negative zonal wind stress anomalies over the equatorial Indian Ocean, along with a 12º eastward shift in the center of action in these anomalies. This combined effect of the increased amplitude and eastward shift in the zonal wind stress increases the SSHA variance over the Indian Ocean, increasing its contribution to the ITF variation. The decadal ITF changes discussed in this study will be crucial in understanding the future global climate variability, strongly coupled to Indo-Pacific interactions.
Modularity of Bershadsky–Polyakov minimal models
Authors: Fehily Zachary , Ridout David 
Published: May 2022

AbstractThe Bershadsky–Polyakov algebras are the original examples of nonregular W-algebras, obtained from the affine vertex operator algebras associated with $$\mathfrak {sl}_3$$

sl
3

by quantum Hamiltonian reduction. In Fehily et al. (Comm Math Phys 385:859–904, 2021), we explored the representation theories of the simple quotients of these algebras when the level $$\mathsf {k}$$
k
is nondegenerate-admissible. Here, we combine these explorations with Adamović’s inverse quantum Hamiltonian reduction functors to study the modular properties of Bershadsky–Polyakov characters and deduce the associated Grothendieck fusion rules. The results are not dissimilar to those already known for the affine vertex operator algebras associated with $$\mathfrak {sl}_2$$

sl
2

, except that the role of the Virasoro minimal models in the latter is here played by the minimal models of Zamolodchikov’s $$\mathsf {W}_3$$

W
3

algebras.
Virgilio nel Purgatorio di Dante: poesia, politica e morale
Authors: Ledda Giuseppe 
Published: May 2022

AbstractLa presenza di Virgilio nelPurgatoriodi Dante è complessa e problematica: si tratta di un regno proprio dell’aldilà cristiano, che il poeta latino non ha mai visitato prima e le cui dinamiche gli sono in gran parte ignote. Perciò la sua funzione di guida è messa ripetutamente in discussione, specie nei primi canti, e poi si esaurirà con la sua scomparsa e sostituzione con Beatrice. Al centro del percorso di ascesa c’è l’incontro drammatico e rivelatore con Stazio, che deve il proprio essere poeta ma anche la propria conversione e la propria salvezza a Virgilio, che invece da tale salvezza resta escluso. Ma la poesia di Virgilio è citata continuamente anche nella seconda cantica, e offre tra l’altro numerosi esempi morali del vizio punito nel sistema degli esempi delle cornici purgatoriali, oltre a essere, con il suo poema imperiale, un punto di riferimento per la poesia politica di Dante, riferimento ben presente nella parte centrale della cantica, ma invece trascurato nella parte iniziale e in quella conclusiva, in coincidenza con i momenti di maggiore difficoltà per la guida e di più severa correzione dei suoi testi. Il saggio passa in rassegna questi aspetti della presenza di Virgilio proponendo anche una chiave di lettura che cerca di tenere insieme i suoi aspetti positivi e quelli negativi.
Nonlinear aeroelastic analysis of a damped elastica-aerofoil system
Authors: Jayatilake Sanuja , Titurus Branislav 
Published: May 2022

AbstractThis work formulates a comprehensive model of a nonlinear aeroelastic system developed for the analysis of complex aeroelastic phenomena related to structural and aerodynamic nonlinearities. The system is formulated as a two-dimensional cantilevered elastica with a rigid airfoil section firmly attached at its tip undergoing large displacements in the crosswind conditions. The system can demonstrate a wide range of domain specific as well as coupled nonlinear phenomena. The structural model is developed by means of the Rayleigh–Ritz approach, with shape functions discretizing both vertical and horizontal displacements and Lagrangian multipliers enforcing inextensibility. Damping is modeled based on a non-local strain-based mechanism in the Kelvin–Voigt arrangement. The resulting structural model is examined through studying the behavior under a follower load and with a tip-attached tendon under tension to study the shape convergence properties and the alignment of the results with known characteristics in the literature. The ONERA dynamic stall model is used to model the aerodynamics of the problem to accurately capture post-stall behavior at large deformations. The LCO responses of the aeroelastic problem are evaluated through time-marched simulations, and the combined airspeed–damping interactions are studied in this manner.
Profile of individuals with low back pain and factors defining chronicity of pain: a population-based study in Ethiopia
Authors: Beyera Getahun Kebede , O’Brien Jane , Campbell Steven 
Published: May 2022

Abstract
Purpose
Low back pain (LBP) is the most prevalent public health problem globally, second only to headaches in the ranking of painful disorders that affect human beings. However, evidence about the profile of LBP patients is lacking in low-income countries for appropriate management approaches. This study examined the profile of individuals with LBP and factors defining chronicity of pain in Ethiopia.

Methods
A population-based cross-sectional study design was used to collect data from 1812 adults (≥ 18 years) with LBP at present. Data were collected by interviewing the study participants using an instrument developed and validated in the same study population. The instrument includes socio-demographic information, health behaviours/lifestyle habits, beliefs about pain, and pain and general health-related characteristics of the participants. Data analysis was performed using R version 3.5.1. Both unconditional and conditional logistic regression models were fitted and Odds Ratio (OR) with 95% confidence intervals (95% CIs) were computed to identify factors significantly associated with chronicity of pain at p ≤ 0.05 significance level.

Results
Negative beliefs about pain, a varying degree of pain interference with daily and social activities, complaining of pain in other anatomical sites other than the low back region, general health status rated as not excellent, depressive symptomology, and sleeping problems/insomnia were common within the profile of individuals with LBP. Age, educational level, residential setting, beliefs about pain, and depressive symptomology were found to have a statistically significant association with chronicity of pain.

Conclusions
This study provides an overview of the profile of individuals with LBP and factors defining chronicity of pain, assisting clinicians to design appropriate management strategies to improve patients' outcomes.
Adapted physical activity in subjects and athletes recovering from covid-19: a position statement of the Società Italiana Scienze Motorie e Sportive
Authors: Venturelli Massimo , Mancini Annamaria , Di Cagno Alessandra , Fiorilli Giovanni , Paneroni Mara , Roggio Federico , Musumeci Giuseppe , Buono Pasqualina , Schena Federico , Paoli Antonio 
Published: May 2022

AbstractCoronavirus disease 2019 (COVID-19) is a worldwide pandemic illness that is impacting the cardiovascular, pulmonary, musculoskeletal, and cognitive function of a large spectrum of the worldwide population. The available pharmacological countermeasures of these long-term effects of COVID-19 are minimal, while myriads of non-specific non-pharmacological treatments are emerging in the literature. In this complicated scenario, particular emphasis should be dedicated to specific exercise interventions tailored for subjects and athletes recovering from COVID-19. Specific guidelines on adapted physical activity in this critical population are unavailable so far, therefore, in this position statement of the Società Italiana di Scienze Motorie e Sportive (SISMeS) the members of the steering committee of the research group Attività Motoria Adattata, Alimentazione, Salute e Fitness have indicated the adapted physical activity approaches to counteract the long-term effects of the COVID-19, both in good health people and athletes.
Development of a maxillofacial virtual surgical system based on biomechanical parameters of facial soft tissue
Authors: Cheng Mengjia , Zhuang Yu , Zhao Hanjiang , Li Meng , Fan Lingfeng , Yu Hongbo 
Published: May 2022

Abstract
Purpose
Lack of biomechanical force model of soft tissue hinders the development of virtual surgical simulation in maxillofacial surgery. In this study, a physical model of facial soft tissue based on real biomechanical parameters was constructed, and a haptics-enabled virtual surgical system was developed to simulate incision-making process on facial soft tissue and to help maxillofacial surgery training.

Methods
CT data of a 25-year-old female patient were imported into Mimics software to reconstruct 3D models of maxillofacial soft and skeletal tissues. 3dMD stereo-photo of the patient was fused on facial surface to include texture information. Insertion and cutting parameters of facial soft tissue measured on fresh cadavers were integrated, and a maxillofacial biomechanical force model was established. Rapid deformation and force feedback were realized through localized deformation algorithm and axis aligned bounding box (AABB)-based collision detection. The virtual model was validated quantitatively and qualitatively.

Results
A patient-specific physical model composed of skeletal and facial soft tissue was constructed and embedded in the virtual surgical system. Insertion and cutting in different regions of facial soft tissue were simulated using omega 6, and real-time feedback force was recorded. The feedback force was consistent with acquired force data of experiments conducted on tissue specimen. Real-time graphic and haptic feedback were realized. The mean score of the system performance was 3.71 given by surgeons in evaluation questionnaires.

Conclusion
The maxillofacial physical model enabled operators to simulate insertion and cutting on facial soft tissue with realization of realistic deformation and haptic feedback. The combination of localized deformation algorithm and AABB-based collision detection improved computational efficiency. The proposed virtual surgical system demonstrated excellent performance in simulation and training of incision-making process.