bluuebunny/crossref_metadata_2025_split huggingface dataset:
IMPORTÂNCIA DA NUTRIGENÔMICA NA PREVENÇÃO DE DOENÇAS CRÔNICAS NÃO TRANSMISSÍVEIS (DCNT´S)
Authors: Sanches Chimara Emilia Nascimento 
Published: August 2022

Introdução: A alimentação é um fator de influência na modulação da expressão gênica e pode atuar no surgimento das DCNT´s, inclusive nos últimos 50 anos houve um aumento no surgimento dessas doenças devido à alimentação inadequada, rica em ultraprocessados . Após a conclusão do Projeto Genoma em 2003 surgiu a nutrigenômica, e com ela foi possível entender que os nutrientes presentes nos alimentos podem induzir alterações nos padrões de metilação do DNA e na expressão genética. Objetivo: Descrever a influência da alimentação na expressão gênica e sua relação com o surgimento de doenças crônicas não transmissíveis (DCNT´s). Metodologia: Trata-se de uma revisão de literatura, para entender a relação entre os nutrientes da alimentação e a modulação genética. Foram utilizados artigos publicados entre os anos de 2000 a 2021, disponíveis nos seguinte bancos de dados: Scielo, PubMed e Portal BVS. Resultados: A nutrigenômica elucida que tanto os alimentos influenciam na expressão gênica como também os genes determinam a necessidade de consumo de determinados nutrientes, através da hipometilação do genoma e da hipermetilação é possível tanto promover o crescimento desordenado das células como também diminuir o risco de câncer em determinado tecido, sendo assim certos alimentos podem influenciar tanto positivamente como negativamente na homeostase celular. Conclusão: Portanto, apesar de mais estudos serem necessários, já é possível afirmar que com o conhecimento da nutrigenômica é possível melhorar a qualidade de vida e até tratar e prevenir as DCNT´s através de dietas personalizadas para cada indivíduo, potencializando o uso de cada nutriente a favor da homeostase celular.
IMPORTÂNCIA DA MICROSCOPIA E PRESENÇA DA BIOTECNOLOGIA: NO ENSINO DE CIÊNCIAS EM ESCOLAS PÚBLICAS
Authors: Souza Filipe Teixeira Pinheiro de 
Published: August 2022

Introdução: Visualização microscópica de seres, sendo eles de qualquer espécime, é de suma importância para compreensão, da formação e reorganização, do pensamento sobre tudo que nesse vasto mundo e até mesmo, fora dele habita. E juntamente, a biotecnologia carrega consigo o estudo e desenvolvimento de organismos geneticamente modificados e suas utilizações para fins produtivos. Objetivo: relatar a experiência com alunos de escola pública em contato com os métodos experimentais de microscopia, inflando a curiosidade e a busca por conhecer e entender, facilitando o aprendizado para se tornar mais palpável e real o que era visto apenas nos livros, bem como práticas de vivência para questionarem a realidade de como os fenômenos de mudança, criação ou renovação acontecem e como elas estão presentes em seus meios de diversas formas, como pela biotecnologia, sendo ela, de grande importância, não somente, mas para a área da saúde e permitindo que os estudantes possam se reconhecer como membros de uma comunidade e sejam capazes de tomar decisões fundamentadas em conceitos cientificamente atualizados. Material e Métodos: trata-se de um relato de experiência com uma abordagem prática em meio escolar, onde foi aplicado a manipulação do microscópio e a elaboração de lâminas simples de plantas. Resultados: a análise mostrou que após mostrar aos estudantes algo novo e diferente, não visível sem auxílio do microscópio, o interesse pelas práticas laboratoriais, exclusivamente a microscopia, aplicada naquele momento, se nota um aumento em relação à realidade anterior. Conclusões: se pode concluir, que pode-se fazer um esforço maior nas escolas ou para com que se mantenha essas práticas, inclusivas de laboratórios ou meios simples de reconhecimento e aprendizado da visualização microscópica, pois com isso, nossos pequenos estudantes possam sempre questionar “por quê” e “como” os levando a cada vez mais ser um ser crítico científico e rico em conhecimento e em vontade de aprender mais, assim superando suas barreiras.
PENGARUH BALANCE EXERCISE TERHADAP TINGKAT KESEIMBANGAN POSTURAL DALAM MENURUNKAN RESIKO JATUH PADA LANSIA
Authors: Muladi Amik 
Published: August 2022

Pendahuluan; Penuaan merupakan proses terjadinya degenarasi jaringan dimana fungsi tubuh mengalami penurunan sehingga menyebabkan terjadinya gangguan keseimbangan postural, yang dapat mengakibatkan peningkatan resiko jatuh pada lansia. Gangguan keseimbangan postural dapat dikendalikan dengan terapi non farmakologi yaitu dengan balance exercise.
Tujuan; Penelitian ini untuk mengetahui pengaruh balance exercise terhadap tingkat keseimbangan postural dalam menurunkan resiko jatuh pada lansia.
Metode; Penelitian ini menggunakan desain pre-eksperimen dengan one group pretest-posttest, dengan 20 responden. Pengumpulan data menggunakan lembar observasi. Variabel bebas adalah balance exercise, sementara variabel terikat adalah keseimbangan postural. Teknik pengambilan sampel menggunakan purposive sampling. Populasi dalam penelitian ini adalah lansia di Desa Badran dan Desa Jungke. Analisa data menggunakan wilcoxon.
Hasil; Terdapat pengaruh balance exercise terhadap peningkatan keseimbangan postural pada lansia. Hasil uji wilcoxon didapatkan p value = 0,001 (< α). Sebelum melakukan balance exercise terdapat 18 (90%) responden yang mengalami gangguan keseimbangan sedang, dan 2(10%) responden mengalami gangguan keseimbangan kurang. Setelah dilakukan balance exercise dari 20 responden terdapat 14 (70%) responden mengalami peningkatan keseimbangan dalam kriteria baik sedangkan 6 (30%) responden pada keseimbangan sedang.
Kesimpulan; Terdapat peningkatan keseimbangan postural pada lansia setelah dilakukan balance exercise.
Prospects for the search for new biologically active compounds among the derivatives of the heterocyclic system of 1,2,4-triazole.
Authors: SAMELİUK Yurii , KAPLAUSHENKO Andrii , NEDOREZANIUK Natalia , OSTRETSOVA Liusine , DİAKOVA Feodosiia , GUTYJ Bogdan 
Published: August 2022

The authors are not native speakers of Turkish

The purpose of this literature review was to systematize data from studies of the biological activity of 1,2,4-triazole derivatives with substituents in positions 4 and 5. The authors set the task of forming an idea of current directions in the selection of substitutions for 1,2,4-triazole based on research.
As a result of the study, 75 literature sources were analyzed. This made it possible to form a further vector in terms of searching for biologically active structures among 1,2,4-triazole derivatives. The review develops a modern approach to the search for biologically active substances among 1,2,4-triazole derivatives. Systematized data on the nature of substituents in the core of 1,2,4-triazole, which affect a specific type of activity.
The search material was selected over the past decade with the highest number of citations at the time of literature analysis.
Pensamiento maternal, afectos y emociones en la canción “Parto” (2015) del dúo Barone-González
Authors: Suppicich Fernanda 
Published: August 2022

“Parto” es un tango compuesto e interpretado por el dúo que integran Patricia Barone y Javier González, y está incluido en su disco Complicidad (2015)1. A partir de esta canción me propongo reflexionar, desde una perspectiva feminista, sobre cómo se expone musicalmente el concepto de maternidad en el tango de este siglo. Partiendo del estudio de teorías feministas, indago primero en la historia del dúo, su conformación, y en las composiciones que tienen temáticas afines a “Parto”, en articulación con los movimientos de derechos humanos. En un segundo momento, analizo la maternidad en este tango en relación al momento político y social en el que se estrena, el cual se cruza con las acciones feministas de reclamo por la legalización del aborto y la no violencia por razones de género. En este sentido, estudio cómo el arte dialoga con la formación de afectos, emociones y subjetividades colectivas y en qué medida el objeto de estudio se inscribe, a partir de un género musical como el tango, históricamente heteronormado y androcéntrico, en el movimiento feminista y en el movimiento de derechos humanos como un acto político.
[1] Para apreciar esta versión ver: https://www.youtube.com/watch?v=J4XPHgg9Mo0
Diagnostic accuracy of uterine artery doppler velocimetry in patients with placenta previa
Authors: Gebreil Mohammed Mohammed , El-Sadek Ahmed Mohammed , Emam Khaled Gaber 
Published: August 2022

Background; The placenta previa (PP) is an obstetric problem in which the placental tissue is improperly located inside the lower uterine segment. Aim and objectives: was to see how effective uterine artery Doppler velocimetry was in detecting unusually morbidly adhering placentas in patients who had had one or more prior caesarean sections with placenta previa. Subjects and methods; Cross-sectional research of 100 patients was undertaken in the Department of Gynecology and Obstetrics, El- Sayed Galal Hospital, AL- Azhar University. Result; Our results showed highly statistically significant correlation between the presence of abnormal lacunae and histopathological confirmation (P-value > 0.001). In addition, the overall Sensitivity, specificity, PPV, NPV and accuracy were 90%, 100%, 100%, 64.2%, 91.6%. This criterion showed very high sensitivity and specificity with very high positive predictive value and accuracy to become the most important criteria, Conclusion; As a result of this, we conclude that the accuracy of abnormal placental lacunae, loss of the reto-placental clear zone, myometrial thinning, and utero-vesical hypervascularity are the most critical ultrasound criteria for diagnosing placenta accreta in patients who had a previous CS with a placenta previa overlying the previous uterine scar.
Impact of HCV ns5a resistance associated substitutions on treatment outcome of chronic HCV in daclatasvir-based antiviral regimens
Authors: Esmat Gamal Eldin , Zekri Abdel-Rahman N , El-Sayed Mohammad , Soliman Hany K , Medhat Eman , Daif Mohamed Abo El Kassem Abo 
Published: August 2022

Background: RASs have direct relation to the treatment outcome in chronic HCV patients receiving DAAs. Aim and objectives: to evaluate prevalence of NS5A HCV RASs and their impact on the treatment outcome in daclatasvir-based antiviral regimens in a cohort of Egyptian patients. Subjects and methods: This study was conducted on 40 Egyptian chronic HCV patients at the virology unit of Cairo Fatemya hospital. The study participants were recruited from cases attending the virology unit of Cairo Fatemya hospital in the period from 1/11/2019 to 1/6/2020. Those patients were divided to two equal groups: responders and non responders (20 patient each).Result:Significant difference was found between the two groups as regard RAS in NS5A region in amino acid position 332 (K substitution was detected in responders while E substitution was detected in non-responders), There was a significant difference between the two groups of studied patients as regard RAS in NS5A region in amino acid position 28 (L substitution was found in responders while M substitution was found in non-responders).Conclusion; Although our results showed that RASs against NS5A and NS5B inhibitors have impact on treatment outcome, this finding needs to be confirmed by a larger study.
Effect of iron deficiency on behavior and cognition in children
Authors: Bahgat Karima Abd Elfattah , Nasr Haidy Mahmoud , El-Sayed Samar Kamel 
Published: August 2022

Background: Iron deficiency (ID) is the most common trace element deficiency in childhood. More than 25% of the world’s population is affected by anemia, of which more than 50% suffers from iron deficiency anemia (IDA). Iron deficiency can cause changes in neurotransmitter homeostasis, decrease myelin production, impair synaptogenesis, and decline the function of the basal ganglia. Therefore, IDA adversely affects cognitive functions and psychomotor development. Aim: is to study the effect of iron deficiency on behavior and cognitive function in children using conners parent rating scales and P300 event-related potentials (ERPs). Patients and Methods: This is a cross sectional comparative study included 20 children with iron deficiency, 20 children ​with iron deficiency anemia,and 20 healthy children who attended the pediatric out patient’s clinic and inpatient department of Al-Zahraa hospital –Alazhar University for Girls we include children with iron deficiency ,Children with chronic medical conditions,Children with co-morbid psychiatric diagnoses ,children with any form of psychiatric, physical, developmental or Intellectual disability, chronic underlying disease (e.g. inborn error of metabolism, genetic, endocrine or liver disease, vision or hearing impairment) or neurologic disorders were excluded from the study.
Correlation between optical coherence tomography angiography macular parameters with optical coherence tomography structural parameters in primary open angle glaucoma (a longitudinal descriptive study)
Authors: Abdelghani Hasnaa Hussien Kamel , Ahmed Mansour Hassan , Haroun Hazem Effat , Aboud Safaa AwadAllah Mohamed 
Published: August 2022

Background: There is growing evidence indicating that glaucoma pathogenesis is attributed to vascular dysfunction.Aim: compare the macular circulation in normal individuals and glaucomatous patients in the superficial as well as the deep retinal plexuses, to determine and characterize macular circulation deficits in glaucoma along with correlating them with structural macular OCT parameters Methods: descriptive study included 100 eyes of 100 participants who were selected randomly from attendants of ophthalmology outpatient clinic in Beni-suef university hospital Participants were subjected to 24-2 SITA- standard automated VF test using SAP ,OCT ONH examination and OCTA (Macula) Results: IOP showed significant negative moderate to strong linear correlation with all the Macular Parameters in Glaucoma Participants. These correlations were highly significant; (p-values <0.001). All measurements of superficial and deep macular venues plexuses by studied macular OCTA was statistically significantly lower in glaucomatous as compared to non-glaucomatous participants; (p-values <0.001). Conclusion: There was a reduction in VD in particular that of superficial layer in POAG patients in macular region, according to OCTA measurements. Glaucomatous eyes have a significantly sparser superficial VD in the macula when compared to healthy eyes, and these VD assessments are significantly accompanied by the severity of VF destruction and OCT structural affection.
Optical coherence tomography angiography versus fluorescein angiography in diagnosis of ischemic diabetic maculopathy
Authors: Ahmed Mansour Hassan , Haroun Hazem Effat Abd Elghany , Aboud Safaa Awad-allah Mohamed , Ahmed Sanaa Aiad El Sayed 
Published: August 2022

Objectives: To compare between the use of Fundus Fluorescein Angiography (FFA) and Optical Coherence Tomography Angiography (OCTA) in the diagnosis and quantification of diabetic macular ischemia (DMI) diagnosed according to the Early Treatment Diabetic Retinopathy Study (ETDRS) classification based on Foveal avascular zone (FAZ) parameters. Patients and Methods: The presented study is a prospective randomized observer blind observational study that included 40 eyes of 25 diabetic patients who were diagnosed as having ischemic diabetic maculopathy. Diabetic patients (type 1 or type 2) having different severities of diabetic retinopathy with and without previous treatment (laser or intravitreal injections). FA and OCTA images were independently graded by 2 observers that reached agreement regarding quantitative DMI according to established protocols. Quantitative analysis of the FAZ area was performed using custom software. Results: Demographic data of the studied cases were comparable between groups. OCTA images closely correlated with FA regarding area of FAZ (mm2).
Preface: 2022 International Conference on Biochemical Engineering and Environmentally Friendly Material (BEEFM 2022)
Authors: Gunther Miranda , Pan Disheng 
Published: August 2022

2022 International Conference on Biochemical Engineering and Environmentally Friendly Material (BEEFM 2022) was successfully held online from May 14 to 15, 2022 in Xi'an, China. The conference invited scholars and experts in the fields of chemistry, biology, environmental engineering and materials application from various universities and institutes, to participate in the review and guidance of this conference. The conference focuses on the latest research fields, and provides an international cooperation and exchange platform for experts, scholars and business managers in these fields.
The aim of BEEFM 2022 is to share the research achievements, discuss the key challenges and research directions of the development, and jointly promote the industrialization cooperation and continuous innovation of international academic achievements. This collection of proceedings compiles oral and paper presentations submitted by the authors and scrutinized by the special committee.
Due to travel restrictions and indoor activities related to COVID-19, we were forced to move BEEFM 2022 online. Attendees were notified one month in advance that the on-site conference was changed to an online conference. The online conference was held on the video conferencing software. Because of the wide coverage of this conference and the large number of attendees, we divided the conference into main session and sub-sessions. The opening ceremony was held in the main session and a speech was delivered by the invited speaker. After the main session, we divided the participants into three sub-sessions. Each author spoke for about 15-20 minutes on detailed material in the slides, with the same amount of time set aside for questions and discussion. The format of questioning and discussion was that after each author's introduction, the conference chairman and committee members asked and answered questions. At least one attendee could ask questions that will be answered by the speaker.
BEEFM 2022 had brought together many excellent works, latest ideas and concepts. New ideas have been provided in the fields of chemistry, biology, environmental engineering and materials application. Look forward to meeting again next year.
BEEFM 2022 Conference Scientific Committees
Xi'an, China
Gli enti sportivi di ispirazione religiosa. Il caso del ‘Centro Sportivo Italiano’
Authors: Ivaldi Maria Cristina 
Published: August 2022

SOMMARIO: 1. Osservazioni introduttive circa la disciplina degli enti religiosi alla luce del codice del Terzo settore - 2. Cenni al binomio sport-religione - 3. Il caso del Centro Sportivo Italiano (CSI) - 4. Brevi considerazioni conclusive alla luce del documento “Dare il meglio di sé”.
Religious inspired sports bodies. The ‘Centro Sportivo Italiano’ case.
ABSTRACT: After an overview and highlighting of the most recent changes introduced to the Code of the Third Sector and of the wide range of interplay and frictions between religion and sport, from a legal perspective, the contribution focuses on the religious inspired sports bodies. Among these, the paper discusses the case of the Centro Sportivo Italiano and examines its statutes and association pact that outline the Catholic religious orientation. The essay ends by considering the 2018 document “Giving the best of yourself” of the Dicastery for the Laity, Family and Life, which can be described as the first real Catholic manifesto on the Catholic perspective on sport and human person.
Santa Sede e debito illegittimo.Il cammino verso la Corte internazionale di giustizia (2015-2022)
Authors: Coppola Raffaele 
Published: August 2022

SOMMARIO: 1. Il discorso del Santo Padre Francesco (Santa Sede in senso proprio) ai membri dell’Assemblea Generale dell’Organizzazione delle Nazioni Unite - 2. La posizione della Santa Sede in senso lato e dei vertici della Chiesa italiana - 3. Odierne prospettive nella linea di lavoro politico - 4. La via africana sul debito - 5. Argentina e Fondo Monetario Internazionale (FMI).
Holy See and illegitimate debt. The path to the International Court of Justice (2015-2022)
ABSTRACT: This work offers a synthesis of the main steps of the process towards the International Court of Justice, accomplished over a seven-year period by the Holy See and the Cartel of jurists inspired by the Charter of Sant’Agata de’ Goti – Declaration on Usury and International Debt (1997). The starting point is Holy Father Francis’ speech at the United Nations General Assembly (New York, September 25, 2015), where the devastating deviations of speculative finance were condemned. Next, the points of convergence with the positions taken on the matter by the Italian Bishops’ Conference (CEI) are described, as well as today’s perspectives on debt and the International Court of Justice, in the line of political engagement, with regard to the Gentiloni government and the first Conte government. Completing the discussion is a report on what the author calls the African way on debt and an in-depth look at the differences from a recent wide-ranging initiative aimed at resolving the long-standing issue of the Argentine debt.
Validazione della versione italiana della White Fast-track Scoring Criteria: uno studio prospettico osservazionale
Authors: Casati Paola , Sansone Claudia Maria 
Published: August 2022

INTRODUZIONE: Nelle ore immediatamente successive alla dimissione dalla sala operatoria i pazienti sottoposti a intervento chirurgico sono soggetti a eventi avversi. La scala “White Fast-Track” è adatta a rilevare precocemente il rischio di complicanze postoperatorie, tuttavia, non risulta esser validata in italiano. Inoltre, per consentire una sorveglianza post-operatoria complete, dovrebbe essere completata con parametri aggiuntivi.
OBIETTIVI: Questo studio si propone di tradurre e validare in italiano la scala “White fast-track scoring criteria” e di realizzarne una versione modificata per ottenere una valutazione più completa degli interventi di chirurgia maggiore.
METODI: Studio quantitativo, osservazionale, prospettico, monocentrico, su un campione non randomizzato di pazienti di almeno 18 anni, sottoposti a chirurgia generale, toracica, vascolare, urologica, ortopedica, ginecologica, endocrinologica, mammaria, naso-gola o facciale, nella sala di rianimazione di un ospedale universitario di Milano.
RISULTATI: Sono stati arruolati 250 pazienti. La scala originale ha mostrato una buona affidabilità inter-rater, consistenza interna e affidabilità test-retest; lo stesso vale per la versione modificata. La scala originale ha permesso di identificare 18 pazienti a rischio; la versione modificata ne ha identificati 20 che avrebbero potuto essere dimessi secondo i criteri originali e che in realtà hanno sviluppato complicanze postoperatorie.
DISCUSSIONE: La versione italiana della “White fast-track scoring criteria” sembra attestarsi come uno strumento valido e può essere utilizzato dal personale infermieristico per effettuare un'adeguata sorveglianza postoperatoria finalizzata a prevenire le complicanze postoperatorie precoci.
CONCLUSIONI:La versione modificata riflette la reale sorveglianza effettuata in recovery room e mostra affidabilità, sensibilità e specificità soddisfacenti rispetto allo strumento originale