bluuebunny/crossref_metadata_2025_split huggingface dataset:
CARACTERIZAÇÃO DE PARÂMETROS FÍSICO-QUÍMICOS DA ÁGUA EM TRECHOS DO RIO PURAQUEQUARA SOB INFLUÊNCIA DE ABATEDOURO BOVINO EM MANAUS- BRASIL
Authors: Queiroz João , Souza Filho Elton , Souza David , Sarkis Gisele , Albuquerque Carlossandro , Batista Ieda 
Published: January 2022

Com intuito de analisar a qualidade físico-química das águas em trechos do rio Puraquequara, sob influência de atividades de abatedouro bovino, foram feitas medições do, temperatura, oxigênio dissolvido, condutividade elétrica, sólidos totais dissolvidos, turbidez, fósforo total e nitrogênio total. Foram realizadas seis campanhas amostrais,m sete pontos, com avaliação sazonal das águas entre 2018 e 2019. Dentre os dois períodos, os parâmetros da água do rio mostraram- se ser mais propensos a alterações na vazante. Os resultados apresentaram temperatura oscilando entre 29,21°C à 30,91°C e aeração OD≥4,72 mg.L-1. Valores de pH>6, condutividade de 56,78 µS.cm-1, turbidez 24,85 FTU, sólidos totais dissolvidos 29,00 mg.L-1 , fósforo total 0,32 mg.L-1 e nitrogênio total 3,7 mg.L-1 indicam alteração destes parâmetros frente às condições naturais do rio, influenciados pelo abatedouro.
Antineoplastic Drugs as a Cause of Drug Induced-Immune Hemolytic Anemia, Resulting in Major Intravascular Hemolysis Leading to Acute Kidney Injury Requiring Renal Replacement Therapy
Authors: Bay Pierre , Buob David , Gabarre Paul , Rondeau Eric , Fillon Julie , Gibier Jean-Baptiste , Luque Yosu , Modot Thomas , Doreille Alice , Rafat Cedric 
Published: January 2022

Abstract
Background
Drug-induced immune hemolysis (DIIHA) is rare and may involve antineoplastic agent. Life threatening DIIHA complicated with severe acute kidney injury (AKI) has hitherto seldom been reported and had yet to be scrutinized from a clinical standpoint.
Methods
Over a five-month period we admitted in our intensive care unit three patients with KDIGO stage 3 AKI along with, hemolytic anemia and thrombocytopenia within 24-hours following the administration of antineoplastic agent. These three women underwent anti-neoplastic treatment for metastatic colorectal cancer.
Results
All three patients presented with 1) abrupt immune intravascular hemolysis along with thrombocytopenia 2) a positive direct antiglobulin test (DAT) positive for IgG 3) absence of schistocytes 4) and AKI requiring replacement therapy. All patients had multiple previous exposure to the drugs received. Kidney biopsy was performed for patient 1, displaying acute tubular necrosis lesions interpreted as pigment nephropathy. Investigations in patients 2 and 3 highlighted high-titers of specific oxaliplatin-dependent antibodies. Hemolysis resolved within 14 days post-chemotherapy for all three patients. The renal outcome was favorable.
Conclusions
Antineoplastic drugs can elicit abrupt immune hemolysis and thrombocytopenia, resulting in severe AKI. Thorough explorations are warranted to confirm DIHA, incriminate the offending drug on proper grounds while exonerating other pharmacological therapies, a chief concern in the setting of cancer therapy so not to needlessly reduce anti-cancer treatment options. The outlook for renal recovery seems favorable.
Noise Exposure During Minimally Invasive Benign Prostatic Hyperplasia Laser Surgery Procedures
Authors: Xia Shengqiang , Tong Zhen , Shi An , Sun Jie 
Published: January 2022

Abstract
Objective: To monitor the occupational noise exposure during minimally invasive benign prostatic hyperplasia (BPH) laser surgery procedures in the operating room.Methods: A wireless noise level meter was used to monitor the noise exposure to the surgeon and patients during different BPH laser surgery procedures. The sound level were recorded during 180-W Photoselective vaporization of the prostate surgery (Realton Co., Beijing,China ), 100-W Holmium laser enucleation of the prostate(HoLEP, VersaPulse Power-Suite, Lumenis Ltd),90-W HoLEP (Dahua Laser Co., Jiangsu, China) and 60-W HoLEP (VersaPulse Power-Suite, Lumenis Ltd). Maximum peak level and time-average decibel level were measured. State Anxiety Inventory (S-AI) scores of 37 surgeons from 5 hospitals after an 8-h working day for different laser surgery were recoreded.Results: The mean background sound levels in the operation room prior to laser surgery was 48dB within a range of 40~54 dB. A maximum sound level of 91 dB was recorded at level of surgeon’ head during the working of 100-W HoLEP machine, while the mean decibel level was 85dB. Use of the 90-W HoLEP machines achieved the lowest mean decibel level (66 dB) recording both at level of surgeon’s and patient’s head. The sounds during 180-W PVP ranged from 60~77 dB at level of surgeon’s head and 60~75dB at patients’s head. The State Anxiety score was significantly higher in the 100-W HoLEP group compared with other groups (P<0.05).Conclusions: Our data showed the noise exposure during minimally invasive benign prostatic hyperplasia procedures. A modified cooling system in 90-W HoLEP machine could effectively reduce the noised emitted by the laser generator. Surgeons may experience uncomfortable and anxiety after an 8h working day for HoLEP. Music and noised-induced headphones may help to reduce negative emotion.
COVID-19 Vaccination Mandates and Vaccine Uptake
Authors: Karaivanov Alexander , Kim Dongwoo , Lu Shih En , Shigeoka Hitoshi 
Published: January 2022

Abstract
We evaluate the impact of government-mandated proof of vaccination requirements for access to public venues and non-essential businesses on COVID-19 vaccine uptake. We find that the announcement of a mandate is associated with a rapid and significant surge in new vaccinations (more than 60% increase in weekly first doses), using the variation in the timing of these measures across Canadian provinces in a difference-in-differences approach. Time-series analysis for each province and for France, Italy and Germany corroborates this finding. Counterfactual simulations using our estimates suggest the following cumulative gains in the vaccination rate among the eligible population (age 12 and over) as of October 31, 2021: up to 5 percentage points (p.p.) (90% CI 3.9-5.8) for Canadian provinces, adding up to 979,000 (425,000-1,266,000) first doses in total for Canada (5 to 13 weeks after the provincial mandate announcements), 8 p.p. (4.3-11) for France (16 weeks post-announcement), 12 p.p. (5-15) for Italy (14 weeks post-announcement) and 4.7 p.p. (4.1-5.1) for Germany (11 weeks post-announcement).
Next-Generation Sequencing-based Test for Resectable Colorectal Cancer in Real-World Clinical Practice
Authors: Ogiri Masayo , Seishima Ryo , Nakamura Kohei , Aimono Eriko , Matsui Shimpei , Shigeta Kohei , Chiyoda Tatsuyuki , Tanishima Shigeki , Okabayashi Koji , Nishihara Hiroshi , Kitagawa Yuko 
Published: January 2022

Abstract
Purpose:

This study aimed to evaluate the significance of Next-generation sequencing (NGS)-based gene panel testing in resectable colorectal cancers (CRC)s by analyzing real-world data collected prospectively from patients.
Methods:

Patients with CRC who underwent surgery from July 2018 to February 2020 at our institution were included, and correlations between various NGS data and clinicopathological findings were evaluated.
Results:

Overall, 107 patients were included in this study. The tumor stage was I in 28 cases (26.2%), II in 40 cases (37.4%), III in 32 cases (29.9%), and IV in 7 cases (6.5%). Actionable gene alterations were found in 97.2% of the cases. Co-alteration analysis suggested that either TP53- or APC-related alterations were more frequently found in early-stage tumors (stage I). The copy number alteration count was significantly lower in right side colon tumors than in tumors in other locations (P < 0.05). Homologous recombination deficiency (HRD) was more often identified in stage IV tumors than in stage I or II tumors (P < 0.05). Moreover, high HRD status was suggested to be useful for identifying high-risk stage II tumors (P < 0.05).
Conclusion:

In this study, real-world NGS data represented the biological features of CRCs. HRD was identified as a useful result of gene panel testing with novel utility in clinical practice.
Study On Green Output Bias of China’s Mariculture Technological Progress
Authors: Ji Jianyue , Sun Yanan , Yin Xingmin 
Published: January 2022

Abstract
With the rapid development of mariculture, environmental pollution is becoming more and more serious. It is particularly important to study the green output bias of technological progress for the long-term sustainable development of mariculture. Based on the input-output data of the mariculture in 10 Chinese coastal areas from 2008 to 2018, the DEA-Malmquist index decomposition method is used to calculate output-biased technological progress index and combines with the change of marginal substitution rate of output factors in different periods to identify the bias of technological progress between output factors, and analyze the green output bias of mariculture technological progress. The results show that green technological progress is a crucial factor affecting green total factor productivity’s growth in China’s mariculture. During the study period, the number of regions where technological progress tends to reduce pollutant emissions shows a fluctuating upward trend, and the degree of technological progress toward green output is high. There are obvious differences among regions. The green output bias of technological progress in the South China Sea area is the highest, followed by the East China Sea area, and the Bohai Sea area is poor. Specifically, the green output bias of technological progress in Fujian, Guangdong and Hainan is higher, while the green output bias of technological progress in Tianjin, Hebei, Shandong and Guangxi is lower. According to the research results, corresponding policy suggestions are provided to realize the green and sustainable development of China’s mariculture.
Assessment of Risk Factors on Eye Dryness in Young Adults Using Visual Display Device both in Contact Lens Wearers and Non-wearers
Authors: Altinbas Ekin , Elibol Alperen , Fıratlı Göktuğ , Ayhan Cemre , Celebi Ali Riza Cenk 
Published: January 2022

Abstract
PURPOSE

Researchers are interested in examining the impact of visual display devices (VDDs) on the development of dry eye illness because their use is becoming more common among college students. The goal of this study was to see if there was a link between certain risk factors and the development of eye dryness in VDDs using young adults who wore contact lenses and those who didn't.
METHODS

The self-administrated survey was hosted in Google Forms, sent via e-mail to the participants. It consisted of two parts of assessing different risk factors (i.e. environmental conditions, angle of gaze, years of VDD use) with contact lens use and Ocular Surface Disease Index (OSDI) questionnaire. The OSDI scores of the entire sample who suffer from dry eye and the subgroup using contact lenses were calculated. The relationship between different risk factors with the OSDI scores was also assessed.
RESULTS

274 young adults from college students and academic staff (216 female, 58 male) were suffering from eye dryness. 88 of the 274 participants wore contact lenses. The mean OSDI scores of the 274 young adults was 32.92. Mean OSDI scores in contact lens wearers and non-wearers were 34.36 and 32.24 respectively (p<0.01). There was a statistically significant relationship between OSDI score and indoor environmental conditions in computer using VDD group. Using a computer in a dark environment and above the line of sight resulted in a higher OSDI scores. Females who wore contact lenses whilst using a computer for more than three years had significantly higher OSDI scores than non-wearer females. Tablet type VDD use increased the mean ODSI scores of the contact lens wearers significantly.
CONCLUSIONS

Dry eye symptoms were shown to be increased in the contact lens wearer group with the increased duration of computer VDD use, decreased indoor environmental brightness conditions, and above the line of sight.
Assessment of the Value of Regional Water Conservation Services Based on SWAT Model
Authors: Zhang Xianqi , Chen Peng , Dai Shengnan , Han Yonghua 
Published: January 2022

Abstract
The quantitative evaluation of water conservation in the Luoyang area can provide a basis for decision-making on regional water resources development and utilization, ecological environmental protection and economic development planning. Based on the SWAT model and alternative engineering method, the water conservation and its service value in Luoyang region from 2009 to 2018 were assessed and the reasons for their spatial and temporal changes were analyzed. The results show that during the period of 2009-2018, the total water connotation and its service value reached the highest in 2014, with 16,927,100 m3 and 103 million yuan, respectively; the total water connotation and its service value reached the lowest in 2011, with 7,073,500 m3 and 43,224,000 yuan, respectively. Forest ecosystems have a strong water retention and storage capacity, and the highest water conservation and service value. Precipitation is the most important factor influencing water conservation and service value. The value of water-supporting services per unit area of ecosystem in Luoyang area is forest, grassland, arable land and urban in descending order.
Natural variation MeMYB108 associated with tolerance to stress-induced leaf abscission linked to enhanced protection against reactive oxygen species in cassava
Authors: Liao Wenbin , Wang Bin , Li Shuxia , Zou Liangping , Guo Xin , Liang Jiaxin , Peng Ming 
Published: January 2022

Abstract
The reactive oxygen scavengers play important roles in regulating the cassava ( Manihot esculenta Crantz) leaf abscission induced by stresses. To date, the relationship between natural variations of MYB genes and reactive oxygen scavengers under drought in cassava genotypes remains unclear. Here, we reported the transcription factor MeMYB108 played a positive role in regulating leaf abscission exposed to drought in cassava. The expression levels of MeMYB108 in abscission zones of cassava leaf pulvinus were higher in cassava genotype SC124, which were less easy to shed leaves under stress than cassava genotype SC8 when the leaf abscission induced by drought condition was identical. For the transgenic cassava, overexpression ofMeMYB108 significantly reduced the drought-induced leaf abscission rate, while the interference expression increased leaf abscission rate under the same condition. The consecutively two-year analysis of reactive oxygen scavengers showed significant differences among different cassava genotypes under drought-induced leaf abscission, indicating the relevance between reactive oxygen scavengers and leaf abscission. Correlation analysis revealed the natural variation of theMeMYB108 exon was associated with reactive oxygen scavengers during drought-induced leaf abscission. Phylogenetic analysis indicated the MeMYB108 allele enhanced the tolerance of cassava to drought-induced leaf abscission. Complementation transgenic lines containing the elite allele of MeMYB108 SC124 decreased the leaf abscission rate induced by drought conditions, demonstrating natural variation in MeMYB108 contributed to leaf abscission tolerance induced by drought in cassava. Further studies showed MeMYB108 played an active role in the tolerance of cassava to drought-induced leaf abscission by inducing scavenging of reactive oxygen species.
Stock Structure Analysis of Declining Shovel Nosed Lobster Thenus Unimaculatus (Burton and Davie, 2007)for Effective Management and Conservation Along the Indian Coast
Authors: Chakraborty Rekha Devi , Thanku Sarada Pengamuck , Dash Gyanaranjan , Kumar Rajan , Divipala Indira , Muthusamy Rajkumar , Sivasankaran Sreelakshmy 
Published: January 2022

Abstract
Thenusunimaculatus (Burton and Davie 2007)is one of the most important commercially exploited lobster species in India distributed throughout the coast. The declining trends and collapse of the sand lobster fishery has been reported from the northwest coast of India. A number of hypotheses have been proposed to explain the decline, but a lack of basic information on population demographics inhibits hypothesis testing. In this study, morphometric stock structure analysis of Thenusunimaculatus was attempted to discriminate the spawning population collected from five locations (673 specimens) during 2017-2019 along the Indian coast. Data was subjected to allometric transformation to remove size effect. The transformed data was subjected to multivariate analysis, such as Principal Component Analysis (PCA) followed by linear discriminant analysis (LDA) using R software. The first eight PCs cumulatively explained 73.97% of the total variance,wherein the first two PCs together explained 45.50% of the total variance. The accuracy (ACC) and misclassification rate (MR) of the linear discriminant analysis (LDA) model performed to optimize separation among different sampling locations were 0.70 and 0.30, respectively, which indicates clear overlapping of the stocks among different sampling locations.The accuracy (ACC) and misclassification rate (MR) of the linear LDA model developed to discriminatebetween the coasts were 0.74 and 0.26,respectively, indicating no apparent differentiation in the samples between the coasts. The results of this study revealed the presence of asingle spawning stock of shovel nosed lobster, T. unimaculatus along the Indian coast.The information will aid in the development of better holistic management strategy for the conservation of this declining resource.
Evaluation of Psychometric Properties of the Persian Version of the Predicaments Questionnaire, Exploring Social Attitudes to Suicide
Authors: Rafati Ali , Janani Leila , Malakouti Seyed Kazem , Motevalian Seyed Abbas , Kabiri Ali , Pasebani Yeganeh , Shalbafan Mohammadreza 
Published: January 2022

Abstract
Suicide is the second leading cause of death between the ages of 15 and 29. Most suicides are related to mental illnesses. Suicide is considered a response to predicaments. Due to the growing prevalence of suicide, assessing people's attitudes toward suicide is necessary. Therefore, this study aimed to examine the psychometric properties of the Persian version of the Predicaments Questionnaire (PQ), measuring social attitudes toward suicide.Methods:This psychometrics study evaluated face validity, content validity, temporal stability, internal consistency, and exploratory factor analysis. First, the questionnaire was translated into Persian by the translate-back-translate method. The Persian version was provided to 10 experts in psychiatry for further revision. Two indicators, CVR and CVI, were calculated to evaluate the content validity. To check the face validity, we prepared a form and gave it to 10 people outside the campus to submit their opinions. The results were then given to 10 experts to comment on.Temporal stability was investigated by the test-retest method, reporting Intraclass correlation (ICC). Internal consistency was assessed by reporting Cronbach's alpha and McDonald’s Omega coefficients. Exploratory factor analysis was used to determine the number of dimensions of the questionnaire. In this analysis, χ2, TLI, CFI, RMSEA, and SRMR indices were calculated. All analyses were performed using SPSS software version 22 and R software version 4.Results:A total of 151 students were enrolled with a mean age of 25 (SD=0.32). The Persian PQ was valid in terms of content validity and face validity. Furthermore, it was reliable as Cronbach’s alpha, McDonald’s Omega, and the ICC were 0.94, 0.943, and 0.998, respectively. In addition, the exploratory factor analysis yielded one dimension. Finally, after reviewing the experts’ comments, the final amendments were made, and only question 29 was removed from the final version.Conclusion:Consequently, the Persian version of the PQ is acceptable in terms of content validity, face validity, temporal stability, and internal consistency. This questionnaire can be used in future research on Persian-speaking society.
Normal and Tangential Force Modeling and Control of Single Crystal Silicon Using Wire Saw Velocity Reciprocation
Authors: Wang Jiabin , Li Shujuan , Liang Lie , Hao Zheng , Liu Feilong 
Published: January 2022

Abstract
Single crystal silicon wafer is widely used as the substrate material for integrated circuits, and the wafer is cut by wire saw with fixed diamond abrasive owning to the wire saw’s narrow kerf, low cutting force. The cutting force changes during the process operation since the wire change motion direction continuously (i.e., reciprocation) in order to effectively leverage the wire, even if the contact length of wire and part and wire saw tension are fixed, leading to wire saw breakage, wafer collapse, and inferior surface roughness. This paper established the model of cutting force that includes normal force and tangential force, and design the controller for regulating the force via wire velocity control, and the controller obtains the relationship between the normal force and commanded wire velocity. A PI controller experimental studies for Single crystal Silicon wafer wire saw machining are conducted. The results show the controller can well regular the cutting force generated when wire saw machines silicon and on that the wire saw machining process with PI control can decrease wafer surface roughness as compared to the cutting process with a constant wire velocity reciprocation.
Causality analysis of CO2 emissions, foreign direct investment, gross domestic product, and energy consumption: Empirical evidence from SAARC countries
Authors: Mozahid Md. Nur , Akter Sharmin , Iqbal Md. Hafiz 
Published: January 2022

Abstract
Over the period 1980-2016, this study looks into the causal relations among CO2 emissions, energy consumption (EC), foreign direct investment (FDI), and gross domestic product (GDP) in SAARC countries. To achieve the research objectives, panel unit root tests, panel cointegration autoregressive distributed lag model, and Granger causality tests are used. In the long-run, income has a positive impact on CO2 emissions, while squared income has a negative impact, confirming the occurrence of the Environmental Kuznets Curve (EKC) theory in SAARC countries. Among all SAARC countries, Bangladesh and Nepal support the pollution haven hypothesis, but India, Pakistan, and Sri Lanka support the pollution halo hypothesis. EC has a large positive impact on CO2 emissions across the country. In the long-run, the Granger causality test confirms one-way causation from EC to CO2 emissions and bidirectional causality of FDI and CO2. As a result, these countries might encourage clean energy technology through FDI without jeopardising GDP and environmental quality. This will allow these countries to reduce CO2 emissions to achieve a long-term green GDP and combat global warming.