bluuebunny/crossref_metadata_2025_split huggingface dataset:
A systematic model of stable seller–buyer matching with true preference induction in E-commerce platform
Authors: Gao Tai-Guang , Ye Qiang , Huang Min , Wang Qing 
Published: September 2022

PurposeThis paper mainly focuses on how to induce all members to represent members' true preferences for supply and demand matching of E-commerce platform in order to generate stable matching schemes with more social welfare of Multi-agent Matching Platform (MMP) and individually stable advantages than traditional methods.Design/methodology/approachAn MMP is designed. Meanwhile, a true preference inducing method, Lower-Bid Ranking (LBR), is proposed to reduce the number of false preferences, which is helpful to solve the problem that too much false preferences leads to low efficiency of platform operation and supply and demand matching. Then, a systematic model of LBR-based Stable Matching (SM-LBR) is proposed.FindingsTo obtain an ideal transaction partner, the adequate preference ordering and modifying according to market environment is needed for everyone, and the platform should give full play to the platforms' information advantages and process historical transaction and cooperation data. Meanwhile, the appropriate supply and demand matching is beneficial to improve the efficiency and quality of platform operation, and the design of matching guidance mechanism is essential.Originality/valueThe numerical experiments show that, the proposed model (SM-LBR) can induce members to represent the model's true preferences for stable matching and generate effective matchings with more social welfare of MMP and individually stable advantages than traditional methods, which may provide necessary method and model reference for the research of stable matching and E-commerce platform operation.
Managing campgrounds and “glampgrounds”
Authors: Craig Christopher 
Published: September 2022

Research methodology
Ethnographic interview/observation; analysis of public data; literature review.

Case overview/synopsis
As of 2020, camping was growing in popularity among new and experienced travelers. The growth of the outdoor accommodation type led to for-profit and nonprofit campgrounds operating at or near capacity during peak season. Camping Coast-To-Coast (CCTC), a for-profit camping business that managed approximately 500 campgrounds in the USA, was struggling to meet growth objectives because they too were operating at or near capacity at most of their campgrounds. This case analyzes a newly proposed strategy: developing glamping campgrounds (i.e. glampgrounds) near CCTC’s existing traditional campgrounds. Glamping is a luxurious form of camping characterized by modern amenities and services. The chief executive officer (CEO) was not only able to identify several opportunities that would support a recommended pilot glampground but also identified several threats and firm weaknesses that could deter travelers from paying premium prices for luxurious glampground accommodations. The CEO was left wondering: should I recommend a new glampground development to investors and board members at an upcoming annual meeting or not?

Complexity academic level
The case was developed with two purposes in mind: to be taught in an outdoor tourism management course (junior level) and to be used for association to advance collegiate schools of business master of business administration accreditation to measure four learning objectives: decision-making, problem-solving, application of business frameworks and writing. Thus, this case is optimal for upper-level undergraduate or graduate management and tourism courses including principles of management, strategic management and tourism management.
Evaluating the utility of telehealth in emergency medicine
Authors: Sri‐Ganeshan Muhuntha , Cameron Peter A , O'Reilly Gerard M , Mitra Biswadev , Smit De Villiers 
Published: September 2022

AbstractThere has been great interest regarding tele‐emergency care (TEC) and its utility following the COVID‐19 pandemic. We have seen a roll out of multiple TEC services across Australia, operating in isolation, without coordination and under differing models of care, creating the potential for an uncoordinated, inefficient healthcare system. We outline a potential framework under which TEC services might function as part of the current system, defining potential strategies that may be used to appropriately coordinate the acute care of select patients outside of the ED as well as improve the efficiency of the physical ED itself.
Hybrid electrosynthesis as non‐genetic approach for regulating microbial metabolism towards waste valorization in circular framework
Authors: Sravan J. Shanthi , Mohan S. Venkata 
Published: September 2022

AbstractBiogenic waste (solid/liquid/gaseous) utilization in biological processes has disruptive potential of inclining towards carbon neutrality, while producing diverse products output. Anaerobic fermentation (methanogenesis and acidogenesis) routes are crucial bioprocesses for production of various renewable chemicals (carboxylate platform/organic acids, short/medium chain alcohols, aldehydes, biopolymers) and fuels (methane, hydrogen, hythane, biodiesel and electricity), while individual operations posing process limitations on their conversion efficiency. Advantageous benefit of using the individual bioprocess technicalities is of utmost importance in the context of sustainability to conceptualize and execute integrated waste biorefinery. The opinion article intends to document/familiarize the waste‐fed biorefinery potential with application of hybrid advancements towards multiple product/energy/renewable chemical spectrum leading to carbon neutrality bioprocesses. Unique and notable challenges with diverse process integrations along with electrochemical/interspecies‐redox metabolites‐materials synergy/enzymatic interventions are specifically emphasized on application‐oriented waste feedstock potential towards achieving sustainability.
A guide for developing a field research safety manual that explicitly considers risks for marginalized identities in the sciences
Authors: Rudzki Elizabeth N. , Kuebbing Sara E. , Clark David R. , Gharaibeh Burhan , Janecka Mary J. , Kramp Rachael , Kohl Kevin D. , Mastalski Talia , Ohmer Michel E. B. , Turcotte Martin M. , Richards‐Zawacki Corinne L. 
Published: September 2022

Abstract

Field research can be an important component of the career trajectories for researchers in numerous academic fields; however, conducting research in field settings poses risks to health and safety, and researchers from marginalized groups often face greater risks than those experienced by other researchers in their fields; If these additional risks are not actively and thoughtfully mitigated, they are likely to hinder the participation of qualified investigators in field research and counteract efforts to improve and promote diversity, equity and inclusion in the field sciences.

Here we provide, from our perspectives as co‐authors of a field safety manual for the Department of Biological Sciences at the University of Pittsburgh in Pennsylvania, United States, (A) background on risks and barriers that should be considered when planning and conducting field research and (B) suggestions on how to work as a collaborative team for developing an inclusive field safety manual.

As an example of a manual this proposed process has yielded, we have included our own field safety manual written with diversity, equity and inclusion as a central focus.

We hope this publication serves as a starting point for those interested in developing a similar document for use in their laboratory group, department or institution.
Simulated genetic efficacy of metapopulation management and conservation value of captive reintroductions in a rapidly declining felid
Authors: Magliolo M. , Naude V. N. , van der Merwe V. C. , Prost S. , Orozco‐terWengel P. , Burger P. A. , Kotze A. , Grobler J. P. , Dalton D. L. 
Published: September 2022

AbstractIn South Africa, cheetahs (Acinonyx jubatus) occur as a relictual, unmanaged population of ‘free‐roamers’, a managed metapopulation across fenced reserves, and in various captive facilities. To ensure that the Cheetah Metapopulation Project (CMP) is not at risk of losing overall genetic variation to drift or inbreeding, we propose various interventions, including exchanges between free‐roamers and the metapopulation or supplementation with unrelated individuals from captivity. Simulated trajectories of genetic diversity under such intervention strategies over time could directly inform conservation action and policy towards securing the long‐term genetic integrity of the CMP. Single Nucleotide Polymorphisms (SNPs) were genotyped for 172 adult cheetahs across the free‐roamer population, the metapopulation, and three major captive facilities. Management intervention trajectory models were tested including, (1) no intervention, (2) genetic exchange between free‐roamers and the metapopulation, (3) translocation from a single captive facility and (4) translocation from several captive facilities into the metapopulation. Discriminant Analysis of Principal Components (DAPC) showed that two captive populations are highly differentiated from the metapopulation and each other, whilst the third captive and free‐roamer populations are genetically more similar to the metapopulation. Simulated genetic variation over 25 generations indicated that models 1 and 2 show significant losses of heterozygosity due to genetic drift and present a proportional increase in the frequencies of 1st‐ and 2nd‐degree relatives, whilst this variation and pairwise relatedness remain relatively constant under models 3 and 4. We emphasise the potential importance of captive facilities as reservoirs of genetic diversity in metapopulation management and threatened species recovery.
Multicentre randomised trials in anaesthesia: an analysis using Bayesian metrics
Authors: Seretny M. , Barlow J. , Sidebotham D. 
Published: September 2022

SummaryAre the results of randomised trials reliable and are p values and confidence intervals the best way of quantifying efficacy? Low power is common in medical research, which reduces the probability of obtaining a ‘significant result’ and declaring the intervention had an effect. Metrics derived from Bayesian methods may provide an insight into trial data unavailable from p values and confidence intervals. We did a structured review of multicentre trials in anaesthesia that were published in the New England Journal of Medicine, The Lancet, Journal of the American Medical Association, British Journal of Anaesthesia and Anesthesiology between February 2011 and November 2021. We documented whether trials declared a non‐zero effect by an intervention on the primary outcome. We documented the expected and observed effect sizes. We calculated a Bayes factor from the published trial data indicating the probability of the data under the null hypothesis of zero effect relative to the alternative hypothesis of a non‐zero effect. We used the Bayes factor to calculate the post‐test probability of zero effect for the intervention (having assumed 50% belief in zero effect before the trial). We contacted all authors to estimate the costs of running the trials. The median (IQR [range]) hypothesised and observed absolute effect sizes were 7% (3–13% [0–25%]) vs. 2% (1–7% [0–24%]), respectively. Non‐zero effects were declared for 12/56 outcomes (21%). The Bayes factor favouring a zero effect relative to a non‐zero effect for these 12 trials was 0.000001–1.9, with post‐test zero effect probabilities for the intervention of 0.0001–65%. The other 44 trials did not declare non‐zero effects, with Bayes factors favouring zero effect of 1–688, and post‐test probabilities of zero effect of 53–99%. The median (IQR [range]) study costs reported by 20 corresponding authors in US$ were $1,425,669 ($514,766–$2,526,807 [$120,758–$24,763,921]). We think that inadequate power and mortality as an outcome are why few trials declared non‐zero effects. Bayes factors and post‐test probabilities provide a useful insight into trial results, particularly when p values approximate the significance threshold.
When pouches cannot empty: a cohort study of the symptoms this causes, the reasons it's happening, and the treatments needed
Authors: Nugent Emmeline , Church James M. 
Published: September 2022

AbstractBackgroundPatients with an ileal pouch have a new system of defecation. The expulsive peristalsis of the rectum is replaced by the inertia of the pouch. Defecation becomes dependent on gravity and patients are prone to inefficient pouch‐emptying. Several factors can impact pouch emptying and here we review a series of patients to illustrate these factors and their variable presentations.MethodsThis is a retrospective, descriptive study of a series of patients who had undergone total proctocolectomy with ileal pouch anal anastomosis and presented with pouch dysfunction. Patients underwent investigations including, pouchoscopy, pouchography and anorectal physiology testing.ResultsThere were 34 patients, 18 men, mean age 48.4 years. Thirty‐one had a J‐pouch and 3 an S‐pouch. Twenty‐eight had a stapled and 6 a hand‐sewn anastomosis. Presenting complaints included difficulty emptying the pouch (n = 17), high stool frequency (n = 8), clinical bowel obstruction (n = 7), and nocturnal incontinence (n = 3). Diagnoses were anal stenosis (11), afferent‐limb syndrome (n = 7), pouch twist (n = 4), paradoxical puborectalis contraction (n = 7), efferent‐limb spasm/stenosis (n = 2), mega‐pouch (n = 3), pouch prolapse (n = 1), and pouch‐rectal anastomosis (n = 1). Treatments included anal dilation (n = 11), disimpaction (n = 2), biofeedback (n = 2), pouch excision (n = 2), laparotomy with lysis of adhesions (n = 6), Botox injection into puborectalis (n = 6), catheter drainage (3), and miralax (n = 11). All patients with a stenosis had some improvement after dilation, and surgery restored pouch function.ConclusionsAccurate diagnosis and effective treatment of pouch dysfunction is based on an appreciation of pouch physiology, correction of anatomic abnormalities that impair emptying, and management of stool consistency.
Interpretation of computed tomography of the cervical spine by non‐radiologists: a systematic review and meta‐analysis
Authors: Wani Suhail , Fitzgerald Mark C. , Varma Dinesh , Mitra Biswadev 
Published: September 2022

AbstractBackgroundAfter trauma, clearance of the cervical spine refers to the exclusion of underlying serious injuries. Accurate assessment of computed tomography (CT) is commonly required prior to clearance of the cervical spine. Delays to clearance can lead to prolonged immobilization with associated patient discomfort and adverse effects. This systematic review aimed to determine performance of non‐radiologists to evaluate cervical spine CT.MethodsMEDLINE, EMBASE, Cochrane library with sources of grey literature and reference lists of selected articles were appraised from inception to April 2021. We included manuscripts that reported discordance in CT cervical spine interpretation between non‐radiologists and radiologists. The Newcastle–Ottawa scale (NOS) was used to assess quality of included studies and statistical heterogeneity was assessed using the I2 statistic.ResultsThere were 43 studies identified for eligibility and 4 manuscripts included in the final analysis. There were two studies that reported on the performance of radiology residents, one study on the performance of surgical residents and one on emergency physicians. The pooled discordance was 0.25 (95%CI 0.21–0.28) but was lower for radiology residents (range 0.007–0.05). There was significant statistical heterogeneity (I2 = 99.6%, P < 0.001) among studies.ConclusionThere is a paucity of evidence documenting the ability of non‐radiologists in accurately interpreting CT of the cervical spine. A number of discordant findings suggest that studies with larger sample sizes are indicated to accurately ascertain the ability of non‐radiologists in this area.
Economic burden of complications and readmission following oesophageal cancer surgery
Authors: Browning Alison F. , Chong Lynn , Read Matthew , Hii Michael W. 
Published: September 2022

AbstractBackgroundOesophageal cancer is the seventh most prevalent malignancy globally, and the sixth most common cause of cancer‐related death. Oesophageal cancer is also one of the most costly cancers to treat. The aim of this study was to assess the financial impact of post‐operative morbidity and hospital readmissions following oesophagectomy for oesophageal cancer.MethodsA retrospective analysis was performed on a prospectively maintained database of patients with oesophageal cancer who underwent an oesophagectomy at a single centre between July 2014 and June 2019 (N = 56). Readmission costs were also assessed in this cohort for 12 months post‐operatively.ResultsThe total median cost for oesophagectomy in this cohort was AU$57 250. Major complications occurred in 40% of patients, with a median total admission cost of AU$74 606, significantly higher than patients with either minor or no complications (median admission cost of AU$52 713, P < 0.001). Patients whose operation was complicated by an anastomotic leak had a higher median admission cost than those without a leak (AU$104 328 and AU$54 972 respectively, P < 0.001). Cost centres representing the greatest proportion of costs were theatre resources and surgical ward care (medical and nursing). A total of 110 readmissions in 25 patients were recorded in the 12 months post‐operatively, the majority for gastroscopy and dilatation of anastomotic stricture.ConclusionPost‐oesophagectomy morbidity greatly increases cost of care. In addition to the clinical benefits, interventions to minimize post‐operative complications are likely to result in substantial cost savings.
Female fecundability is associated with pre‐pregnancy allostatic load: Analysis of a Chinese cohort
Authors: Hong Xiang , Yin Jiechen , Zhao Fanqi , Wang Wei , Ding Xiaoling , Yu Hong , Wang Bei 
Published: September 2022

AbstractIntroductionAllostatic load (AL) is a practical index that reflects multi‐system physiological changes which occur in response to chronic psychosocial stress. This study investigated the association between female pre‐pregnancy allostatic load and time to pregnancy.Material and methodsWe enrolled 444 women who met the inclusion criteria and were attempting to achieve pregnancy. Their allostatic load scores at baseline were evaluated by nine indicators (systolic blood pressure, diastolic blood pressure, fasting plasma glucose, plasma cortisol, noradrenaline, interleukin‐6, hypersensitive C‐reactive protein, high density lipoprotein cholesterol and body mass index). The participants were followed up and their pregnancy outcome ascertained 1 year later; we then calculated time‐to‐pregnancy. Cox models were used to estimate fecundability ratios and their 95% confidence intervals (95% CI) for different allostatic load scores.ResultsThe median allostatic load score was 1 with a range of 0–6. The females were divided into four groups according to allostatic load score: group A (allostatic load = 0, 150/444, 33.8%), group B (allostatic load = 1–2, 156/444, 35.1%), group C (allostatic load = 3–4, 100/444, 22.5%) and group D (allostatic load = 5–6, 38/444, 8.6%). The cumulative pregnancy rate over 12 months for the four groups (A–D) was 55.4%, 44.5%, 50.9% and 26.9%, respectively (log‐rank test, p = 0.042). After adjusting for potential confounding factors, group D showed a 59% reduction of fecundability compared with group A (fecundability ratio = 0.41, 95% CI 0.21–0.83).ConclusionsWomen with a higher allostatic load score may have lower fecundability. Our findings suggest that the assessment of allostatic load during pre‐conception consultation would be highly prudent.
ZuraGard™: Being second with a better product
Authors: Ash Stephen R. 
Published: September 2022

AbstractIn course of developing an anticoagulant and antibacterial catheter lock solution, we demonstrated that the components and alcohol formed an effective skin antiseptic. Ash Access formed a sister company to focus on development and clinical trials of this skin preparation and exchanged intellectual property for part ownership. Zurex Pharma now has Food and Drug Administration (FDA) approval on the new pre‐operative skin preparation, ZuraGard™, and has made successful steps toward production and marketing of the product. The steps toward FDA approval, the size of the market, and user needs are clearer for a second product in the field than for the first.
Therapeutic window of opportunity in the acute uveitic phase of Vogt–Koyanagi–Harada disease: Prevention of late autoimmune complications by early intervention
Authors: Abu El‐Asrar Ahmed M. , Al Rashed Faisal A. , AlBloushi Abdulrahman F. , Tobaigy Mohannad F. , Gikandi Priscilla W. , Herbort Carl P. , Opdenakker Ghislain 
Published: September 2022

AbstractPurposeTo determine relationship between timing of treatment initiation and disease outcomes and whether a therapeutic window of opportunity exists in initial‐onset acute uveitis associated with Vogt–Koyanagi–Harada disease.MethodsRetrospective analysis of 112 patients (224 eyes). Main outcome measures were final visual acuity, progression to chronic recurrent evolution, development of complications, particularly ‘sunset glow fundus’, and drug‐free remission cure of uveitis.ResultsForty‐six patients (92 eyes) presented in the phase preceding anterior segment (AS) inflammation (early presentation) and 66 patients (132 eyes) had AS inflammation at presentation (late presentation). In significantly more eyes in the early presentation group (85.9%), final visual acuity of 20/20 was achieved compared with those in the late presentation group (66.7%) (p = 0.001). None of the eyes in the early presentation group progressed to chronic recurrent evolution and none developed ‘sunset glow fundus’, whereas in the late presentation group, 28.8% of the eyes progressed to chronic recurrent evolution (p < 0.001) and 56.1% developed ‘sunset glow fundus’ (p < 0.001). Patients in the early presentation group were able to discontinue treatment without relapse of inflammation at significantly shorter time intervals compared to patients in the delayed presentation group (p < 0.001). In the late presentation group, logistic regression analysis demonstrated that presenting clinical features predicting unfavourable outcomes were posterior synechiae (odds ratio = 4.03; 95% confidence interval [CI] = 1.29–12.23), bullous exudative retinal detachment extending to the periphery (odds ratio = 3.35; 95% CI = 1.53–7.32) and female gender (odds ratio = 2.05; CI = 1.08–3.90).ConclusionsOur findings suggest that the window of opportunity lies in the phase preceding AS inflammation and initiation of effective treatment during this phase results in cure of uveitis and prevents blinding complications.