bluuebunny/crossref_metadata_2025_split huggingface dataset:
What psychological interventions are effective for the management of persistent physical symptoms (PPS)? A systematic review and meta‐analysis
Authors: Swainston Katherine , Thursby Stacie , Bell Blossom , Poulter Hannah , Dismore Lorelle , Copping Lee 
Published: July 2022

AbstractObjectivesPresentation of persistent physical symptoms is associated with increased health care utilization, yet clinical outcomes often remain suboptimal. This systematic review aimed to determine whether psychological interventions are effective for the management of PPS and if so, what are the features of the interventions and at what level of care are they delivered. The review also set out to establish which symptoms in those diagnosed with PPS can be effectively managed with psychological intervention.MethodsStudies were included if they clearly reported a psychological intervention, specified the study sample as adults with a diagnosis of persistent physical symptoms, included a comparator and as a minimum an outcome measure of somatic symptoms. Risk of bias was assessed using the EPHPP. Meta‐analysis was conducted to estimate the overall effect of interventions on somatic symptoms (the primary outcome), anxiety and depression (secondary outcomes).ResultsSeventeen papers of varying quality indicated that psychological interventions can be effective for the management of somatic symptoms reported by individuals with PPS within a primary care setting. Psychological interventions were also found to be effective at reducing depression symptoms in individuals with PPS in twelve of the included studies. However, the meta‐analysis results suggest that the psychological interventions utilized within eleven of the included studies did not significantly impact anxiety symptoms.ConclusionsPsychological interventions have some success in managing somatic symptoms in PPS patients within primary care settings although their effects on other psychological symptoms is more mixed. The review highlights the importance of establishing a clearer diagnostic classification to inform treatment trajectories and the need for appropriate training and support within a multi‐disciplinary team to enable the provision of such therapies.
Lived experience of CamAPS FX closed loop system in youth with type 1 diabetes and their parents
Authors: Hood Korey K. , Garcia‐Willingham Natasha , Hanes Sarah , Tanenbaum Molly L. , Ware Julia , Boughton Charlotte K. , Allen Janet M. , Wilinska Malgorzata E. , Tauschmann Martin , Denvir Louise , Thankamony Ajay , Campbell Fiona , Wadwa R. Paul , Buckingham Bruce A. , Davis Nikki , DiMeglio Linda A. , Mauras Nelly , Besser Rachel E. J. , Ghatak Atrayee , Weinzimer Stuart A. , Fox D. Steven , Kanapka Lauren , Kollman Craig , Sibayan Judy , Beck Roy W. , Hovorka Roman ,   the DAN05 Consortium
Published: July 2022

AbstractAimTo examine changes in the lived experience of type 1 diabetes after use of hybrid closed loop (CL), including the CamAPS FX CL system.Materials and MethodsThe primary study was conducted as an open‐label, single‐period, randomized, parallel design contrasting CL versus insulin pump (with or without continuous glucose monitoring). Participants were asked to complete patient‐reported outcomes before starting CL and 3 and 6 months later. Surveys assessed diabetes distress, hypoglycaemia concerns and quality of life. Qualitative focus group data were collected at the completion of the study.ResultsIn this sample of 98 youth (age range 6‐18, mean age 12.7 ± 2.8 years) and their parents, CL use was not associated with psychosocial benefits overall. However, the subgroup (n = 12) using the CamAPS FX system showed modest improvements in quality of life and parent distress, reinforced by both survey (p < .05) and focus group responses. There were no negative effects of CL use reported by study participants.ConclusionsClosed loop use via the CamAPS FX system was associated with modest improvements in aspects of the lived experience of managing type 1 diabetes in youth and their families. Further refinements of the system may optimize the user experience.
Sterling's farewell symphony: The end of the Sterling Area revisited
Authors: de Bromhead Alan , Jordan David , Kennedy Francis , Seddon Jack 
Published: July 2022

AbstractWhen and why did Sterling Area countries stop holding sterling as the majority of their foreign exchange reserves? This paper takes a comparative approach to examine the relative importance of various determinants of adherence to sterling in its declining years as an international currency. Using an original cross‐national panel dataset covering the period 1965–79, we conduct survival analysis which systematically evaluates a comprehensive set of economic and political factors, at the country level as well as in international relations, about when and why countries chose to diversify their reserves away from sterling. Our results highlight the significance of international transactional factors in influencing adherence to sterling, while the effects of British geopolitical retrenchment, Commonwealth cultural ties, and distributional issues were more ambiguous and sensitive to local conditions. We also find that domestic political and historical factors, such as democracy and imperial legacy, played a role in sterling's international unravelling. Finally, we use our results to examine the experience of individual sterling countries and their decisions to diversify.
Facial emotion recognition and schizotypal traits: A systematic review of behavioural studies
Authors: Zouraraki Chrysoula , Karamaouna Penny , Giakoumaki Stella G. 
Published: July 2022

AbstractAimPrevious research has indicated that individuals expressing high schizotypal traits and patients with Schizotypal Personality Disorder (SPD), show deficits in facial emotion recognition, compared to low schizotypal or control groups. On the other hand, non‐significant findings also exist and the association of facial emotion recognition deficits with the different schizotypal dimensions is not well defined, thus limiting any conclusive outcomes. Therefore, the aim of this systematic review was to further clarify this relationship.MethodsPsychInfo, Web of Science, Scopus and PubMed were systematically searched, and 23 papers with a cross‐sectional design were selected. Nineteen studies examined individuals with high schizotypal traits and four studies evaluated SPD individuals with behavioural facial emotion recognition paradigms and self‐report measures or clinical interviews for schizotypal traits. All selected studies were published between 1994 and August 2020.ResultsAccording to the evidence of studies, high schizotypal individuals and SPD patients have poorer performance in facial emotion recognition tasks. Negative schizotypy was related to lower accuracy for positive and negative emotions and faster emotion labeling while positive schizotypy was associated with worse accuracy for positive, negative and neutral emotions and more biases. Disorganized schizotypy was associated with poorer accuracy for negative emotions and suspiciousness with higher accuracy for disgust faces but lower total accuracy.ConclusionsThese findings are consistent with the vulnerability for schizophrenia spectrum disorders and support the idea that emotion recognition deficits are trait markers for these conditions. Thus, the effectiveness of early‐intervention programmes could increase by also targeting this class of deficits.
A critique of virtual court for intimate partner abuse victims in child welfare cases: Another layer of disadvantage for female victims?
Authors: Parsons Sharon 
Published: July 2022

AbstractThe purpose of this viewpoint and critique is to provide theoretical considerations as to why virtual court may exacerbate the existing disadvantages of intimate partner violence victims in child removal cases. As a backdrop, this paper uses a report of an unnamed but actual victim of intimate partner abuse and her experience in a child removal case in Florida.
Trace‐element composition of zircon in Kofu and Tanzawa granitoids, Japan: Quantitative indicator of sediment incorporated in parent magma
Authors: Sawaki Yusuke , Asanuma Hisashi , Sakata Shuhei , Abe Mariko , Ohno Takeshi 
Published: July 2022

AbstractZircon is one of the most important minerals in geochronologic research. Isotopic ratios and trace elements in zircons are expected to reflect those of their parent magmas. Many geochemical researchers have proposed various discrimination diagrams for zircon to indicate tectonic setting and to identify source rock. Because most detrital zircons accumulated at river mouths are derived primarily from granitoids, the classification of zircon within granitoids is potentially meaningful. In our research, we focused on sediment involvement during granitoid formation and tried to identify trace‐element compositions in zircon that are sensitive to variation in sediment incorporation. To accomplish this, we examined trace‐element compositions of both the granitoids and the included zircons in the Kofu granitic complex and the Tanzawa tonalitic plutons in Japan. Among the high‐field‐strength elements (Th, U, Ta, Nb, Hf, and rare earth elements), only Nb and Ta concentrations in the granitoids increased as the rate of sediment contribution increased. However, the zircon did not show such trends in Nb and Ta content. Zircon Y and P contents exhibited a positive correlation, indicating that xenotime substitution occurs to some extent. Because P exists as pentavalent ions in igneous systems, its presence likely affects the concentrations of pentads in zircon. When we divided the Nb and Ta contents by the P content, it became clear that zircon Nb/P and Ta/P ratios increase depending on sediment involvement. While some exceptions exist, we found that zircon Yb/Gd ratios also respond to sediment involvement. Our data further demonstrated that zircons in granitoids with significant sediment incorporation are characterized by low Ce/P contents, which is partly attributable to monazite crystallization before zircon saturation. This study demonstrates that combining these element ratios is useful for indicating sediment incorporation.
Non‐invasive and rapid quality assessment of thermal processed and canned tender jackfruit: NIR spectroscopy and chemometric approach
Authors: Babu Pritty Sushama , Pulissery Sudheer Kundukulangara , Chandran Sarathjith Madathiparambil , Mahanti Naveen Kumar , Pandiselvam Ravi , Jaganath Bindu , Kothakota Anjineyulu 
Published: July 2022

SummaryThermal processing of tender jackfruit is a promising approach to enhance its shelf life and thereby retain the health benefits associated with its inherent antioxidants and phytochemicals. This research looked at the prospective and suitability of near‐infrared reflectance (NIR) spectroscopy (900–1700 nm) to assess the biochemical properties namely ascorbic acid (AA), total flavonoid content (TFC), and total phenolic content (TPC) of thermally treated (pasteurisation and sterilisation) tender jackfruit stored under different preservatives (2% brine, 0.1% KMS, and 0.3% citric acid) for a period of 5 months. The partial least square regression (PLSR) models were developed by using both raw as well as pre‐processed spectra. The pre‐processing of spectral data diminished the prediction accuracy of models. The models developed with raw spectral data reported best prediction accuracies for AA ( = 0.628; RMSEcv = 0.416 and RPDcv = 1.763), TFC ( = 0.915; RMSEcv = 1.909 and RPDcv = 3.719), and TPC ( = 0.882; RMSEcv = 0.032 and RPDcv = 3.013) as compared to models developed with pre‐processed spectral data. However, the lower prediction accuracies were observed in standard normal variate (SNV) pre‐processed data for AA ( = 0.449; RMSEcv = 0.51), TFC ( = 0.500; RMSEcv = 4.628), and TPC ( = 0.396; RMSEcv = 0.072). The standard error (SEP) values of AA, TPC and TFC were almost 1.5–2 times the standard error of laboratory (SEL); this implies the developed models have excellent performance. The results obtained in the present study affirmed that NIR spectroscopy in conjunction with appropriate chemometric techniques can be used for the rapid assessment of biochemical properties of thermal processed and canned tender jackfruit during transportation and storage.
Trader acceptability of African eggplant (Solanum aethiopicum Shum) genotypes and effect of bio‐control treatments on consumer sensory acceptability
Authors: Joseph Mulindwa , Geoffrey Sseremba , Tom Bbosa , Julian Nakanwagi Mildred , Brian Justus Musubire , Bishop Gerard James , Kabod Nahamya Pamela , Balyejusa Kizito Elizabeth 
Published: July 2022

SummaryApplication of advanced agronomic practices may affect the sensory attributes of plant products. The study determined the trader physical acceptability of farmer preferred African eggplant (nakati) genotypes (E11, E15 and E16); and later studied the impact of bio‐control treatments; Trichoderma spp (TRI). and Arbuscular Mycorrhizal Fungi (AMF) on consumer sensory appeal of genotypes using standard sensory evaluation methods. The trader acceptability of genotypes based on leaf number, succulence, smoothness, colour, and shininess were significantly different; except for the hard‐textured leaves of E11 (P ≤ 0.05). Leaf appearance (E11) and stalk‐leaf quantity (E15 and E16) were preferred by high‐end and low‐end markets, respectively. Consumer sensory acceptability of bio‐control‐treated samples, above 85% of E15 and E16 was liked based on reduced bitterness (P ≤ 0.05). Using descriptive sensory tastes, results showed that soil bio‐control treatment with TRI during the light rain season significantly improved the palatability of E15 and E16. Therefore, use of TRI during light or dry season improves sensory appeal of nakati.
Association between interleukin‐1 receptor antagonist (IL‐1ra) VNTR, gene polymorphism and breast cancer susceptibility in Iranian population: Experimental and web‐based analysis
Authors: Ibrahimi Reza , Ibrahimi Mostafa , jamalzei Behzad , Akbari Mohammad Esmaeil , Navari Mohsen , Moossavi Maryam , Khorasani Milad 
Published: July 2022

AbstractBreast cancer is one of the leading causes of cancer mortality. Growing evidence indicates that interleukins and its polymorphisms are involved in the pathogenesis of breast cancer. Variable number of tandem repeat (VNTR) polymorphism can affect transcription rate, mRNA stability and also the resulting protein expression and activity. Hence, present study aimed to assess the possible association between interleukin‐1 receptor antagonist (IL‐1Ra) VNTR polymorphism, and breast cancer susceptibility in Iranian population. A total of 300 Iranian individuals, 150 breast cancer patients and 150 age‐matched healthy women, were included in this study. DNA extracted by salting out method and genotyping was done using the polymerase chain reaction. The frequency of the allele 2(5% vs. 22%) and the 2/2 genotype (22% vs. 46%) of IL‐1Ra VNTR polymorphism was significantly higher in healthy control compared to breast cancer patient: therefore, A2 allele may play a protective role against breast cancer and its progression (p = .0001 and OR = 0.105, 95% CI: [0.044–0.248]). The allele 2 and 2/2 genotype of the IL‐Ra VNTR polymorphism can be a protective factor against breast cancer susceptibility.
Deletion of serine racemase reverses neuronal insulin signaling inhibition by amyloid‐β oligomers
Authors: Zhou Jing , Zhang Zhiwen , yang Yuanhong , liao Fei , Zhou Piansi , Wang Yan , Zhang He , Jiang Haiyan , Alinejad Tahereh , Shan Ge , Wu Shengzhou 
Published: July 2022

AbstractDysregulation of insulin signaling in the Alzheimer's disease (AD) brain has been extensively reported. Serine racemase (SR) modulates insulin secretion in pancreatic islets. This study aimed to examine whether SR regulates insulin synthesis and secretion in neurons, thereby modulating insulin signaling in the AD brain. Srr‐knockout (Srr−/−) mice generated with the CRISPR/Cas9 technique were used. Using immunofluorescence and fluorescence in situ hybridization, levels of insulin protein and insulin(ins2) mRNA were significantly increased in the hippocampal but not in hypothalamic sections of Srr−/− mice compared with WT mice. Real‐time quantitative PCR revealed that ins2 mRNA from primary hippocampal neuronal cultures of Srr−/− mice was significantly increased compared with that from cultured neurons of WT mice. Notably, the secretion of proinsulin C‐peptide was increased in Srr−/− neurons relative to WT neurons. By examining membrane fractional proteins with immunoblotting, Srr−/− neurons retained ATP‐dependent potassium channels on plasmalemma and correspondingly contained higher levels of p‐AMPK. After treatment with Aβ42, the phosphorylation levels of insulin receptor substrate at serine 616 636 (p‐IRS1ser616,636) were significantly lower, whereas p‐AKT308 and p‐AKT473 were higher in Srr−/− neurons than in WT neurons, respectively. The phosphorylated form of c‐Jun N‐terminal kinase decreased in the cultured Srr−/− neurons relative to the WT neurons upon Aβ42 treatment. In contrast, phosphorylated protein kinase R remained at the same levels. Further, reactive oxygen species were reduced in cultured Srr−/− neurons under Aβ42 treatment relative to the WT neurons. Collectively, our study indicated that Srr deletion promoted insulin synthesis and secretion of proinsulin C‐peptide, thereby reversing insulin resistance by Aβ42. This study suggests that targeting the neuronal SR may be utilized to enhance insulin signaling which is inhibited at the early stage of the AD brain.image
A psychometric network perspective to oral health literacy: Examining the replicability of network properties across the general community and older adults from Brazil
Authors: Soares Gustavo Hermes , Bado Fernanda Maria Rovai , Tenani Carla Fabiana , Ribeiro Santiago Pedro Henrique , Jamieson Lisa M. , Mialhe Fábio Luiz 
Published: July 2022

AbstractObjectivesTo evaluate the replicability of oral health literacy (OHL) network models across the general community and a sample of older adults from Brazil.MethodsData were obtained from two oral health surveys conducted with a total of 1138 participants. OHL was measured using the short form Health Literacy in Dentistry scale (HeLD‐14). A regularized partial correlation network was estimated for each sample. Dimensionality and structural stability were examined via exploratory graph analysis. Network properties compared included global strength, edge weights, and centrality estimates. Model replicability was examined fitting the general community model to the older participants' data.ResultsSix dimensions with the exact same item composition were detected in both network models. Only the Receptivity domain in the older adults sample yielded low structural stability. Strong correlations were observed between edge weights (τ: 0.68; 95% CI: 0.62–0.74) and between node strength estimates (τ: 0.63; 95% CI: 0.36–0.89). No statistically significant differences were found for global strength. The fit of the older adults sample to the HeLD‐14 network structure of the general community sample was satisfactory.ConclusionNetwork models OHL replicated across the general community and a sample of older adults. The psychometric network approach is a useful tool to evaluate the measurement equivalence of OHL instruments across populations.
Covid‐19 and SARS‐CoV‐2 infection in periodontology: A narrative review
Authors: Drozdzik Agnieszka 
Published: July 2022

AbstractThe present review examined the available evidence on possible involvement of gingival tissues in SARS‐CoV‐2 infection. Gingival tissue possess SARS‐CoV‐2 entry and transmission factors, among them ACE2 (angiotensin‐converting enzyme 2) and TMPRSS2 (transmembrane protease serine 2), which are the principal mediators of the virus cell invasion. Clinical observations reveal SARS‐CoV‐2 RNA in periodontal tissues and crevicular fluid, suggesting that the periodontium may act as an entry point for the virus and/or as a dissemination site. The preliminary observations prove infection potential of gingival crevicular fluid and shed epithelial cells from the periodontium. There are also findings on potential associations between periodontitis and Covid‐19 (coronavirus disease 2019). PubMed and Scopus databases were used to search for suitable keywords such as: SARS‐CoV‐2, Covid‐19, oral virus infection, gingival crevicular fluid, oral mucosa, periodontium, gingiva, ACE2, TMPRSS2, Furin, diagnosis, topical treatment, vaccine and the related words for relevant publications. Data extraction and quality valuation of articles were performed by the author. The review addressed seven major domains: periodontal structures as SARS‐CoV‐2 infection site, the periodontal changes under SARS‐CoV‐2 infection, potential associations between periodontitis and Covid‐19, periodontal oral care in Covid‐19, crevicular fluid as potential transmission factor and preventive measures. The search process in PubMed and Scopus was updated up to 31 March 2022. Finally 68 articles were retrieved for the final analysis, from the initial database searches. According to the inclusion criteria articles in English language without any date restriction were included. The included studies were mostly original articles, and published in 2020 and 2021 with the aim to describe Covid‐19 and SARS‐CoV‐2 infection in periodontology. As a conclusion it can be stated that gingival tissues may play a role in SARS‐CoV‐2 infection.
Respiratory events with terlipressin and albumin in hepatorenal syndrome: A review and clinical guidance
Authors: Allegretti Andrew S. , Subramanian Ram M. , Francoz Claire , Olson Jody C. , Cárdenas Andrés 
Published: July 2022

AbstractHepatorenal syndrome‐acute kidney injury (HRS‐AKI) is a serious complication of severe liver disease with a clinically poor prognosis. Supportive care using vasoconstrictors and intravenous albumin are the current mainstays of therapy. Terlipressin is an efficacious vasoconstrictor that has been used for 2 decades as the first‐line treatment for HRS‐AKI in Europe and has demonstrated greater efficacy in improving renal function compared to placebo and other vasoconstrictors. One of the challenges associated with terlipressin use is monitoring and mitigating serious adverse events, specifically adverse respiratory events, which were noted in a subset of patients in the recently published CONFIRM trial, the largest randomized trial examining terlipressin use for HRS‐AKI. In this article, we review terlipressin's pharmacology, hypothesize how its mechanism contributes to the risk of respiratory compromise and propose strategies that will decrease the frequency of these events by rationally selecting patients at lower risk for these events.
The Potential of Children's Rearing Environment to Overcome Genetic Propensity for Low Reading Achievement
Authors: Leve Leslie D. , Harold Gordon T. , Neiderhiser Jenae M. , Natsuaki Misaki N. , Shaw Daniel S. , Ganiban Jody M. , Reiss David 
Published: July 2022

AbstractGenetic studies show that children's reading achievement is in part genetically influenced, and intervention studies show that reading achievement can be increased by environmental interventions. However, correlational and mean‐level analytic strategies are rarely integrated into achievement research, potentially leading to misinterpretation of results. The parent‐offspring adoption design offers a novel opportunity to examine the independent and joint roles of genetic and rearing environmental contributions. The sample included 344 adopted children in first grade and their biological and adoptive parents. Results indicated that adoptees' reading scores were correlated with their biological parents' scores, but not with their adoptive parents' scores, suggesting genetic influences. In addition, examination of mean scores indicated that adoptees' scores were significantly greater than their biological parents' (p's < .001) for all subtests, suggesting promotive effects of the rearing environment. This pattern was present even when biological parents scored >1 standard deviation below the biological parent mean on achievement.