bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spinal Cord Dysfunction Secondary to a Sports/Exercise Event
Authors: Ramos Edwardo , Ortiz-Santiago Ana , Correa-Mendoza Ady 
Published: January 2022

Purpose:
The objective of this paper is to present two young patients with SCDys after participation in a sports/exercise event. The authors aim to raise awareness of these unusual causes with potentially fatal results. The authors want to review literature regarding the diagnosis and treatment and particular rehabilitation issues of SCDys.

Methods:
Two cases of young patients with a history of SCDys consulted the pediatric rehabilitation medicine service.

Results:
Physical examination revealed incomplete paraparesis and neurogenic bladder. Both final diagnoses were confirmed by magnetic resonance imaging or computerized tomography scan. Treatment was aimed at avoiding further/permanent neurological complications in both cases, taking into consideration their respective etiologies.

Conclusion:
SCDys is a nontraumatic spinal cord injury that has different etiologies. This paper presents a SCDys due to an unusual etiology.
Exploring the Value of Neuro-Oncological Rehabilitation within a Neurorehabilitation Setting
Authors: Khoo Teng Cheng , FitzGerald Alasdair 
Published: January 2022

Background:
Cancer rehabilitation is gaining recognition in response to treatment advances, with more survivors living with functional impairments. This study aims to describe the outcomes from neuro-oncological rehabilitation within an inpatient neurorehabilitation setting, focusing on patients with malignancy.

Subjects and Methods:
A review of neuro-oncological admissions from 2009 to 2017 was performed comparing length of stay (LOS), changes in United Kingdom Functional Independence Measure + Functional Assessment Measure (UK FIM + FAM) scores, discharge outcome, and survival between patients with benign and malignant diagnoses.

Results:
One hundred and twenty patients were included (40% with malignancy). Eighteen percent required transfer back to acute setting due to cancer- or treatment-related complications. Having malignancy was associated with a higher rate of acute transfer (34% vs. 7%, x
2 = 13.8, P < 0.01). LOS was not significantly different between the two groups (median difference: 5 days, 95% confidence interval [CI]: −8–18, P = 0.187). While UK FIM + FAM change was significantly lower in the malignant group, the corresponding lower UK FIM + FAM efficiency was not (mean difference: 16, 95% CI: 1–31, P = 0.043 and 0.18, −0.42–0.05, P = 0.114, respectively). The median survival in the malignant group was 3.2 months (95% CI: 2.0–8.4), with survival up to 40.4 months.

Conclusion:
While patient outcomes with benign and malignant diagnoses were similar, the UK FIM + FAM does not capture the full benefit of rehabilitation. Given that patients with malignancy have limited survival, quality of life measures and goal attainment scaling may be more appropriate. Effective and efficient inpatient neuro-oncological rehabilitation in malignancy is deliverable, but collaboration with both oncology and palliative care services is crucial.
Are sputum autoantibodies more clinically relevant in idiopathic pulmonary fibrosis than serum autoantibodies?
Authors: Deng Kuimiao , Luo Qun , Liang Zhenyu , Long Fei , Han Qian , Wang Fengyan , Huang Shuyu , Liao Liyue , Lin Tingting , Chen Rongchang 
Published: January 2022

Background:
The adaptive immune system plays a role in the pathogenesis of idiopathic pulmonary fibrosis (IPF) has been reported previously. However, the association between airway and circulating autoantibodies (AAbs) levels is unclear. The aim of this study is to investigate the link between the AAb levels in airway and circulation in stable patients with IPF.

Materials and Methods:
From June 2016 to March 2017, 21 stable IPF patients and 22 healthy volunteers were recruited. We established Luminex interacting AAbs with bead-antigen complex to detect the immunoglobulin G antibodies levels of ten autoantigens which were matched serum (Se) and sputum (Sp) samples collected from recruited subjects, including Smith (Sm), Anti-ribosomal P antibody (P0), Sjögren syndrome type A antigen (SSA), La/Sjögren syndrome type B antigen (SSB), DNA topoisomerase (Scl-70), histidyl-tRNA synthetase (Jo-1), U1 small nuclear ribonucleoprotein (U1-SnRNP), thyroid peroxidase, Proteinase 3, and Myeloperoxidase. Spearman's rank correlation matrix was applied to explore the associations of Ab profiles between Se and Sp.

Results:
For IPF patients, Spearman's correlation matrix showed multiple intercorrelations among Sp-AAbs and Sp-AAbs (P < 0.05), while only the levels of AAb against Sm and anti-La in Se were correlated with those Sp-AAb counterparts (P < 0.05). For healthy individuals, only anti-La in Se was associated with those Sp-AAb counterparts (P < 0.05). For IPF patients, there was a positive correlation between carbon monoxide diffusing capacity (DLCO)% predicted and Sp-anti-P0 level (r = 0.464, P = 0.034). Forced vital capacity% predicted was positively correlated with Sp-anti-Scl-70 level (r = 0.466, P = 0.033).

Conclusion:
Comparing to Se-AAbs, Sp-AAbs are more associated with clinical parameters in the patients with IPF. In order to better understand the role of autoimmunity in the pathogenesis of IPF, detection of Sp-AAbs for local autoimmune responses may be a good choice.
The effectiveness of olibanum orally disintegrating tablet in the treatment of oral aphthous ulcers
Authors: Soltani Rasool , Saberi Zahra , Ghanadian Syed Mustafa , Taheri Azade , Entezarhojjat Amir 
Published: January 2022

Background:

Boswellia serrata oleo-gum-resin (frankincense; olibanum) has anti-inflammatory, analgesic, and antimicrobial effects. This study aimed to evaluate the clinical effectiveness of frankincense extract in the treatment of oral aphthous ulcers.

Materials and Methods:
In a randomized, double-blind, placebo-controlled clinical trial, patients with aphthous ulcers were randomly assigned to either experimental (Frankincense extract) or placebo groups to use orally disintegrating tablets (ODT) of frankincense and placebo, respectively, four times a day for 3 days. The size of aphthous ulcers and the pain severity by visual analogue scale were recorded at days 0, 2, and 4 and compared between the groups.

Results:
Twenty-five patients in each group completed the study. Olibanum extract ODT significantly reduced the ulcer size on the second (P < 0.001) and fourth (P < 0.001) days as well as the pain score on the second (P = 0.002) and fourth (P < 0.001) days of the intervention compared to placebo. Furthermore, at the end of the intervention, the number of patients with complete ulcer healing and pain relief in the experimental group was significantly more than the placebo group (5 vs. 0, P = 0.02; and 11 vs. 0, P < 0.001, respectively).

Conclusion:
Taking olibanum extract ODTs reduces the ulcer size and pain severity and accelerates the healing process in the oral aphthous lesions.
Hyperuricosuria and hypercalciuria, probable etiologies of functional abdominal pain
Authors: Saneian Hossein , Esteki Behnoosh , Bozorgzad Maryam , Famouri Fatemeh , Mehrkash Mehryar , Khademian Majid , Nasri Peiman 
Published: January 2022

Background:
Functional abdominal pain (FAP) is a common complaint causing several referrals to pediatricians. On the other hand, the most common presentation of hyperuricosuria and also hypercalciuria is chronic/recurrent abdominal pain. Therefore, a hypothesis has been raised; abdominal pain due to hyperuricosuria and/or hypercalciuria may be misdiagnosed as FAP. The current study has aimed to respond to this theory.

Materials and Methods:
This is a case–control study conducted on children diagnosed with FAP based on Rome IV criteria and age-matched normal controls. Blood and random urine samples were taken from healthy children and those with FAP. Random urine samples were examined for calcium, uric acid, oxalate, and creatinine concentrations. Random urine calcium to urine creatinine above 0.2 mg/mg was considered hypercalciuria and random urine uric acid above 0.56 mg/dl, GFR as hyperuricosuria. The data were analyzed using logistic models.

Results:
Hypercalciuric children had a significantly lower chance of FAP (odds ratio [OR] =0.425, 95% confidence interval [CI] =0.204–0.886). Although an inverse association was seen between hyperuricosuria and FAP (OR = 0.693, 95% CI = 0.395–1.214), it was not statistically significant. In stratified analyses by gender for both hyperuricosuria and hypercalciuria, a marginal inverse significant association was seen in male gender (P < 0.1).

Conclusion:
Our study showed that hypercalciuria is significantly in inverse association with FAP but not hyperuricosuria. Therefore, these disorders, particularly hyperuricosuria may not be considered as the possible causes of FAP. Further studies with larger sample size for providing more reliable evidence are recommended.
Comparison of adaptive support ventilation and synchronized intermittent mandatory ventilation in patients with acute respiratory distress syndrome
Authors: Alikiaii Babak , Abbasi Saeed , Yari Hamideh , Akbari Mojtaba , Kashefi Parviz 
Published: January 2022

Background:
Suitable mechanical ventilation strategies can reduce the incidence and severity of ventilator-associated lung injury in patients with acute respiratory distress syndrome (ARDS). In this study, the effects of adaptive support ventilation (ASV) and synchronized intermittent mandatory ventilation (SIMV) on respiratory parameters and arterial blood gases (ABGs) parameters were compared in ARDS patients.

Materials and Methods:
Twenty-four patients were randomly divided into two groups of ASV and SIMV. Patients were followed up for 3 days, and respiratory parameters including rapid shallow breathing index (RSBI), spontaneous breathing rate (SBR), minute volume, and peak inspiratory pressure (PIP) as the primary outcomes and ABG parameters including PaO2, FiO2, PaCO2, HCO3, and PaO2/FiO2 ratio as the secondary outcomes were measured.

Results:
PIP in patients in the SIMV group on the 1st day (P = 0.013), 2nd day (P = 0.001), and 3rd day (P = 0.004) was statistically significantly more compared to those in patients in the ASV group. RSBI, SBR, and minute volume between the ASV and SIMV groups during the 3 days were not statistically significantly different (P > 0.05). The mean arterial blood pressure, heart rate, PaO2, and PH between both groups were similar (P > 0.05). At the end of the 2nd and 3rd days, the level of FiO2 and PaCO2 in ASV was significantly lower than those in ASV group. HCO3 in each of the 3 days in the ASV group was statistically significantly lower than that in the SIMV group (P < 0.050). PaO2/FiO2 ratio in patients in the ASV group in the 3 days was statistically significantly higher than that in the SIMV group (P < 0.050).

Conclusion:
By reducing PIP and improving oxygenation and ABG parameters, ASV mode may be a safe and feasible mode during mechanical ventilation in patients with ARDS.
Virtual Tour Univeristas Bina Darma Berbasis Android
Authors: Putra Muhammad Soekarno , Rizandi Hamim Tezar 
Published: January 2022

Bina Darma University is one of the private universities located in the city of Palembang. In providing information about the institution, Bina Darma University has used several methods, including websites, brochures, TV streaming, radio and social media such as Instagram and Facebok. However, from several existing media, it turns out that it still doesn't provide information about the location of the room and also the places around the campus. In this case, researchers are interested in making an information media application to introduce the area around the campus by using virtual tour technology with Android-based mobile technology with an offline system so that it will be easier, because it can be accessed using smartphones or other android-based gadgets without a connection. Internet. The applications used in the manufacture of Andoid applications are Unity 3D. The development method used in building this virtual tour application of the MDLC (Multimedia Development Life Cycle).
Keywords: Virtual Tour, Unity 3D, Mobile, Android, MDLC
Role of Endometrial Receptivity Array for Implantation failure in In-Vitro Fertilization &amp; Intracytoplasmic Sperm Injection
Authors: Nafees Rabia , Khan Haroon Latif , Khan Yousaf Latif , Awais Aisha , Farooqi Anum , Nisar Rameen 
Published: January 2022

<p><strong>Background &amp; Objective: </strong></p>
<p>Assisted reproductive technique is an evolving field with many recent advances. The success rate is low in developing countries where financial concerns prevail predominantly. This study was designed for the first time in any hospital in Pakistan to determine the role of Endometrial Receptivity Array (ERA) in patients with previous implantation failure to improve pregnancy outcome and to enhance the success rate of in-vitro fertilization &amp; intracytoplasmic sperm injection (IVF/ICSI) because ERA was started for the</p>
<p><strong>Methods:</strong></p>
<p>This study was carried out at the Lahore Institute of Fertility &amp; Endocrinology, Lahore-Pakistan. A total of 16 patients were recruited after taking written informed consent. Only those patients were selected who had previous one or more implantation failures in IVF/ICSI cycles and had at least 2 or more good quality frozen embryos. RNA was obtained from the endometrial sample to check ERA through 238 genes expressed using RNA sequencing. Beta HcG level and scans were performed to confirm the clinical pregnancy.</p>
<p><strong>Results:</strong></p>
<p>All enrolled patients had an ERA test and their embryos transferred according to personalized window of implantation (WOI). A total of 5(31.3 %) patients were stimulated with a long protocol while 11 (68.7%) underwent a short protocol. &nbsp;WOI was receptive in 12 (75%) patients, pre-receptive in 3 (18.2%) and post-receptive in 1 (6.2%), and most of patients showed receptivity at P5 (109-145 hours). Twelve patients (75%) had clinical pregnancy evident by positive beta HCG after embryo transfer. A significant association was found between WOI and receptivity (P&lt;0.05).</p>
<p><strong>Conclusion:</strong></p>
<p>The results of ERA in our study seem promising especially in our patients with previous one or more implantation failures. Although we have limited number of patients keeping in mind its financial constraints especially in developing countries, still ERA is considered a way of hope especially for those patients who have previous implantation failures.</p>
<p>&nbsp;</p>
Anti-Mullerian hormone and associated pregnancy outcomes in females with polycystic ovary syndrome undergoing In vitro fertilization-embryo transfer
Authors: Du Jiacheng , Cao Yuping 
Published: January 2022

<p><strong>Background and Objective</strong><strong>: </strong>Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among reproductive-aged women worldwide. Pregnancy in these women is highly affected by serum levels of Anti-Mullerian hormone (AMH). This study aimed to determine the association of serum AMH levels with pregnancy outcomes in females with polycystic ovary syndrome (PCOS) undergoing in vitro fertilization-embryo transfer (IVF-ET)</p>
<p><strong>Methods: </strong>A total of 200 PCOS patients<strong> </strong>undergoing IVF-ET in the Reproductive Medicine Center, Second People's Hospital of Jingmen, China were included. The patients were divided into two groups, A and B, based on their AMH levels. Serum sex hormones levels and pregnancy outcomes in terms of fertilization, cleavage, implantation, high quality embryo and biochemical &nbsp;and clinical pregnancy rates were compared.</p>
<p><strong>Results: </strong>Mean age of the patients was<strong> </strong>28.74&plusmn;2.07 years in group A and 29.74&plusmn;2.23<sup> </sup>years in group B. Participants in group A had lower serum levels of follicle stimulating hormone (FSH), luteinizing hormone (LH), and testosterone (T) compared to group B. Also, better pregnancy outcomes and lower frequency of pregnancy complications were seen in the participants of group A (P&lt;0.05). AMH serum levels showed high specificity and sensitivity in predicting IVF-ET clinical pregnancy in PCOS patients.</p>
<p><strong>Conclusion: </strong>Serum AMH levels in females with PCOS &nbsp;predict &nbsp;improved sex hormone profile and clinical pregnancy outcomes after IVF-ET</p>
Anatomical Parameters of Eye and Associated Histological Features are Potential Risk Factors for Development of Pterygium
Authors: Aman Sadia , Ather Muhammad Muneeb , Qasim Amanullah , Latif Rabia , Jabeen Rakhshanda , Zehra Uruj 
Published: January 2022

<p><strong>Background and Objectives:</strong> Pterygium occurs throughout the world but the exact pathogenesis is still not clear. The reports on the association between eye anatomical parameters and presence of pterygium is controversial, similarly how the histological features of the pterygium may differ due to these parameters is not known. Thus, the focus of this study was to explore this gap by assessing and comparing the anatomical parameters of eye in pterygium patients and in healthy controls. In addition, histological features of pterygium were assessed and correlated with the eye anatomical parameters of the patients.</p>
<p><strong>Methods:</strong> Forty-one pterygium patients of age range 25-70 years undergoing surgery were included in the study after taking written informed consent. Forty-two age and sex matched healthy controls were also recruited for assessing anatomical eye parameters. Relevant history with demographic details of every subject was obtained. All participants underwent a thorough ophthalmic examination. Assessment of orbital protrusion and interpalpebral distance was measured by millimeter scale. Tear film breakup time (TFBUT) and Schirmer test was used for tear film assessment. Presence of any meibomian gland dysfunction (MGD) was examined by slit lamp. Post-surgical tissue samples from patients were assessed for histological features with H&amp; E, PAS &amp; Verhoeff stains. Data were processed and analyzed by using SPSS version 21.0.</p>
<p><strong>Results: </strong>Eyeball protrusion and MGD was found higher in pterygium patients as compared to controls. Basement membrane fragmentation on histology significantly correlated with the eyeball protrusion (P&lt;0.04) and TFBUT (P&lt;0.020), inflammation significantly correlated with the MGD (P&lt;0.05) while elastosis showed significant correlation with TFBUT (P&lt;0.001).</p>
<p><strong>Conclusion:</strong> It can be concluded that eye anatomical parameters might be the risk factors in the development of pterygium. The correlation between certain histological features &amp; eye anatomical parameters indicate that anatomical eye parameters can be taken as risk factor for recurrence in these patients.&nbsp;</p>
PERBANDINGAN MOTIVASI BELAJAR PESERTA DIDIK YANG MENGGUNAKAN MEDIA GAMBAR DENGAN YANG TIDAK PADA KELAS V DI MI NW LINGKUK BUAK LOMBOK TENGAH TAHUN PELAJARAN 2020/2021
Authors: Husairi Husairi 
Published: January 2022

Pemilihan media pembelajaran bertujuan untuk membantu peserta didik agar dapat mencapai tujuan pembelajaran. Media gambar dapat dijadikan sebagai perantara untuk mendorong motivasi belajar peserta didik. Penelitian ini dilakukan dengan tujuan untuk mengetahui perbandingan atau studi komparasi antara motivasi belajar peserta didik yang menggunakan media gambar dengan yang tidak di kelas V .Adapun yang menjadi sampel dalam penelitian ini adalah peserta didik kelas V MI NW Lingkuk Buak Lombok Tengah. Jenis penelitian yang digunakan dalam hal ini adalah desain kuantitatif yang sifatnya komparasi, teknik analisis data yang digunakan yaitu uji-t dengan teknik analisis Independent-Sample T Test. Hasil dari uji hipotesis menunjukkan bahwa didapatkan t hitung sembesar 12,59 dan t tabel sebesar 1,689 yang diuji pada taraf signitifikan 5 %. Ini berarti Ho dotilak Ha diterima, sehingga kesimpulannya ada perbedaan signifikan motivasi belajar peserta didik yang menggunakan media gambar dengan yang tidak pada kelas V Lingkuk Buak Lombok Tengah
PENINGKATAN KEMAMPUAN GURU DALAM PENYUSUNAN RENCANA PELAKSANAAN PEMBELAJARAN KURIKULUM 2013 MELALUI BIMBINGAN BERKELANJUTAN
Authors: Hadijah Hadijah 
Published: January 2022

Penelitian ini bertujuan untuk mengetahui peningkatan kemampuan guru dalam menyusun Rencana Pelaksanaan Pembelajaran kurikulum 2013 melalui bimbingan berkelanjutan di MTs AS-Syifa, MTS Roudhotul Iman dan MTs Nurul Hidayah Sugal, yang berada pada Kecamatan Panimbang Kabupaten Pandeglang Provinsi Banten, Tekhnik pengumpula data dalam penelitian ini adalah observasi dan diskusi, observasi dipergunakan untuk mengumpulkan data dan mengetahui kompetensi guru dalam menyusun RPP, diskusi dilakukan antara peneliti dengan guru, sedangkan alat pengumpulan data dalam PTKP ini sebagai berikut, lembar observasi yang dilengkapi dengan rubrik yang digunakan untuk memperoleh data tentang kemampuan guru dalam menyusun RPP kurikulum 2013 dan diskusi dilakukan dengan maksud untuk sharing pendapat antara peneliti dengan guru dan guru dengan team teaching. Berdasarkan temuan-temuan yang diperoleh dari hasil pengolahan dan analisis data penelitian ini, maka dapat disimpulkan bahwa pembinaan administrasi akademik berupa penyusunan RPP kurikulum 2013 yang baik sangat signifikan. Dengan kata lain melalui pembinaan pengawas kepada guru mampu meningkatkan kemampuan akademik guru dalam bentuk penyusunan RPP kurikulum 2013 dalam mencapai sasaran kinerja
UPAYA MEMBANGUN MINAT MEMBACA MELALUI PROGRAM BERAKSI BERUGAK LITERASI DI SMP ISLAM MUSTHOFA KAMAL
Authors: Aldi Albani Aldi Albani 
Published: January 2022

Rendahnya minat baca masyarakat Indonesia tampaknya ditanggapi serius oleh pemerintah dengan mengadakan program Gerakan Literasi Nasional. Hal ini tampaknya dimulai dari lembaga pendidikan baik di tingkat dasar, menenengah dan tinggi. Masalah utama dalam meningkatakan minat baca peserta didik khususnya di sekolah tentu bervariasi, adakalanya keterbatasan buku bacaan, tidak ada prasarana yang menunjang kegiatan membaca atau bahkan tidak ada guru yang bisa diteladani dan dapat menginspirasi peserta didik dalam membaca. Berbagai masalah itu coba diselesaikan dengan gerakan literasi di sekolah-sekolah. Begitu juga yang telah kami upayakan di SMP Islam Musthofa Kamal dengan mengadakan program BERAKSI yang bertujuan untuk merangsang kemauan siswa untuk terbiasa membaca dengan menfasilitasi mereka dengan prasarana khusus untuk membaca di sekolah. Metode yang penelitain dalam kajian ini adalah kualitatif deskriptif yang menggambarkan apa adanya dari pelaksanakan sebuah program. Teknik pengumpulan data yang digunakan adalah observasi dan dokumentasi. Analisis dilakukan sejak awal pelaksanaan pengamatan dengan menggunakan teknik Miles and Huberman. Adapun langkah-langkah dalam mewujudkan program tersebut di antaranya; perencanaan, pelaksanaan, evaluasi dan monitoring serta tindak lanjut. Adapun kesimpulan hasil program BERAKSI di SMP Islam Musthofa Kamal antara lain: 1) kemauan peserta didik untuk membaca mulai tumbuh; 2) berugak literasi selalu ramai dikunjungi oleh peserta didik pada jam-jam istirahat; 3) guru dapat memanfaatkan berugak literasi sebagai outdoor class; 4) guru dan staf menyempatkan diri untuk ikut membaca karena melihat peserta didik mulai ramai membaca; 5) perasaan senang dan gembira terpancar dari raut wajah peserta didik yang tengah membaca sambil sekali waktu bercerita dan bercengkrama dengan temannya di berugak literasi. Program BERAKSI merupakan salah satu upaya yang cukup efektif untuk menumbuhkan minat baca peserta didik di lingkungan sekolah.