bluuebunny/crossref_metadata_2025_split huggingface dataset:
Three-Dimensional Evaluation of the Effect of Platelet-Rich Fibrin on Edema in Lower Impacted Third Molar Surgery Performed with Piezosurgery
Authors: Konuk B , Şentürk MF 
Published: September 2022

Background:
Platelet-rich fibrin (PRF) are widely used in impacted lower third molar (IL3M) 7 surgery and its effect on postoperative edema was generally analysed with linear methods.

Aim:
To analyze the effectiveness of platelet-rich fibrin (PRF) applied to the socket after tooth extraction in impacted lower third molar (IL3M) surgery performed with piezosurgery in the reduction of edema observed in the postoperative period, together with conventional (linear) and three-dimensional (volumetric) measurement methods.

Materials and Method:
The study was designed as a prospective randomized split-mouth study and was conducted on 30 patients with bilateral IL3M teeth. Extraction of the patients' IL3M teeth was performed in the same session with the help of piezosurgery. After the extraction, PRF was randomly applied to one socket, but it was not applied to the other socket, which formed the control group. On the first, second, and seventh days after the procedure, volume was measured using 3dMD, and the distance between the topographic guide points was measured using a flexible ruler. The results were analyzed statistically. Alveolar osteitis (AO) presence was also recorded.

Results:
A significant improvement in edema was observed in both groups, but no significant difference was found between the groups (P > 0.05). A moderate correlation was found between the two methods of measuring edema. AO was not seen in any patient.

Conclusions:
Although PRF reduces edema after IL3M tooth extraction and 3dMD is effective in its evaluation, it has no statistical advantage over classical methods.
The Relationship Between Vitamin D Receptor Gene Polymorphisms and Periodontitis in Turkish Individuals with Type 2 Diabetes Mellitus
Authors: Yildiz A Saatman , Üstündağ FD , Tiber PM , Doğan B 
Published: September 2022

Background and Aim:
Vitamin D receptor (VDR) gene polymorphisms have been implicated in the pathogenesis of many diseases, such as periodontitis and diabetes mellitus (DM). The present study aimed to evaluate the distributions of VDR polymorphisms in diabetic individuals with healthy periodontium (DMH), diabetic individuals with periodontitis (DMP), nondiabetic individuals with healthy periodontium (H), and nondiabetic individuals with periodontitis (P).

Material and Methods:
A total of 200 individuals (DMH = 40, DMP = 60, H = 40, and P = 60) were recruited. All clinical periodontal parameters, demographical, and biochemical variables were recorded. Blood samples were collected, and genomic DNA was isolated by Purelink® Genomic DNA Mini Kit. Genotyping of VDR polymorphisms ApaI, BsmI, FokI, and TaqI were determined by real-time polymerase chain reaction (PCR) using allele-specific probes.

Results:
The distribution of the BsmI variant showed differences between DMH and H groups (P = 0.034). In addition, carrying the GG genotype (OR = 0.317; 95% CI = 0.126–0.797; P = 0.013) and the G allele (OR = 2.373; 95% CI = 1.203–4.681; P = 0.012) increased the risk of type 2 DM. Moreover, it was determined that the frequency of CC genotype of FokI variant was higher in DMP compared to DMH (P = 0.046). It was determined that having the CC genotype (OR = 2.706; 95% CI = 1.185–6.176; P = 0.017) and the C allele (OR = 1.917; 95% CI = 0.995–3.694; P = 0.049) increased the risk of periodontitis among diabetic individuals. No differences were detected among groups in the genotype and allele distributions of ApaI and TaqI variants (P > 0.05).

Conclusions:
The present study showed that the BsmI variant was a risk factor for DM among periodontally healthy individuals and the FokI variant for periodontitis among diabetic individuals.
Do Credits Affect Money Supply and Deposits, or Vice Versa, or Interconnected?
Authors: TİRYAKİ Göksel , HASANOV Mübariz 
Published: September 2022

There are different approaches regarding the effect of credits on deposits and money
supply. In particular, the view that banks do not need deposits to create credit has become
increasingly popular. In this paper we empirically investigate the relationship among money
supply, credits and deposits based on the Turkish experience. Specifically, using quarterly
observations on M1, M2, M3, deposits in Turkish Lira (TL-Lira) and Foreign Currency (FX)
deposits as well as credits spanning the December 2005 - September 2021 period we find
that credits have significant effects on money stock and deposits. However, our results also
suggest that credits are not the most important determinant of money supply or deposits.
While our results suggest that credits may generate money and deposits endogenously, this
finding does not imply that money is purely an endogenous variable.
Trabajo autónomo o dependiente, fraude laboral y reformas laborales en México
Authors: Cebreros Jesús Rodríguez 
Published: September 2022

La reforma a la Ley Federal del Trabajo, nacida eminentemente del sector empresarial de México y respaldada por la corriente globalizadora, matizada por el cumplimiento de compromisos en materia de comercio internacional, no ha contribuido, ni en el ámbito sustantivo ni en el ámbito procesal, para otorgar a los trabajadores un escenario pertinente para gozar de un trabajo decente ni tener acceso a una impartición de justicia pronta y expedita, al continuarse violentando principios y derechos fundamentales de los trabajadores.
The potential protective effects of nintedanib against cardiac hypertrophy in vitro and in vivo
Authors: Yuan Wenjin , Zhang Dandan , Liu Shiming , Hua Yuanhong , Zhu Lunjian , Li Wenfeng 
Published: September 2022

IntroductionCardiac hypertrophy is an independent risk factor for heart failure. However, the underlying mechanisms of cardiac hypertrophy are still unclear. Nintedanib is a Food and Drug Administration (FDA) approved therapeutic agent for the treatment of progressive fibrosing lung diseases.Material and methodsIn this study, we examined the effects of nintedanib on cardiac hypertrophy using an in vivo murine model with the transverse aortic constriction (TAC) operation and an in vitro cardiomyocytes model stimulated with Ang II.ResultsNintedanib has a protective effect on cardiac function in TAC mice with decreased heart rates, heart weight/body weight (HW/BW), and reduced plasma levels of creatine kinase-MB (CK-MB) and aspartate aminotransferase (AST). Wheat germ agglutinin (WGA) staining proved that the increased cardiomyocytes sizes in TAC mice were restored by nintedanib treatment. Nintedanib also reversed the decreased plasma levels of oxidative markers nuclear factor erythroid-2-related factor 2 (Nrf2), lipid peroxidation products thiobarbituric acid reactive substances (TBARS), and GSH, as well the increased homocysteine (Hcy) levels in TAC mice. In the in vitro cardiomyocytes model, cells were treated with nintedanib, followed by Ang II stimulation. Nintedanib improved Ang II induction-caused cell injury and oxidative stress in H9C2 cells, as shown by the decreased release of lactate dehydrogenase (LDH), and elevated mRNA levels of GPX1 and HO-1. Mechanistically, we prove that the protective effect of nintedanib is mediated by SIRT1.ConclusionsIn conclusion, this study demonstrates the protective effects of nintedanib on cardiac hypertrophy both in vivo and in vitro, which was attributed to its anti-oxidative activity through regulating SIRT1 expression.
Nachhaltige Bioenergie vom Acker
Authors: Schultz Olaf 
Published: September 2022

Frankfurt a.M. Die Beimischung von Blühpflanzen zu dem hochwachsenden Miscanthus-Gras bringt positive Effekte bei der energetischen Nutzung. Eine neue Studie der Universität Hohenheim belegt den Zusammenhang.
Auf der Suche nach Innovation
Authors: Deininger Olaf 
Published: September 2022

Frankfurt a.M. Mitte Juni gab der Landtechnik-Hersteller Claas bekannt, dass die Firmengruppe ihre Beteiligung am niederländischen Start-up AgXeed B.V. weiter ausbaut. Auch andere Landtechnik-Hersteller investieren in Start-ups.
Konjunkturbarometer der Landtechnik stabil
Authors: Dänzer Dieter 
Published: September 2022

Frankfurt a.M. Der am Donnerstag veröffentlichte Index für die Landmaschinenindustrie in Europa zeigt sich seit Juli auf einem positiven Niveau stabilisiert. Für 2023 sehen die Hersteller ein leichtes Umsatzplus.
Periodic reinforcement of knowledge and attitude towards basic life support skills among the medical undergraduates: A necessity of undergraduate medical education
Authors: Ullal Namratha Ashwin , Sathis Bindiya , Ali Farooqui Mohd. Ehtesham , Ashwini  
Published: September 2022

Introduction and Aim: A sudden cardiac arrest can be a life-threatening emergency with poor survival rates. By learning basic life support (BLS) and practicing simple cardiopulmonary resuscitation (CPR), the patient is likely to survive until arrival of expert medical help. The study therefore aims to determine if trained medical undergraduate students retain knowledge and attitude regarding skills.

Methods: About 150 students in the first year of medical school participated in the current study. The students attended two BLS training sessions of three hours each. The students were evaluated at six weeks and followed up at six months following the initial training session. The psychomotor skills were check-listed, and the performance was scored between 0 to 5. Data on knowledge and attitudes were collected with a pre-validated self-administered questionnaire.

Results: Among the participants, 69% were males, and 33% were females. The mean age group of study subjects was 21 ± three years. The skill scores (p=0.001) and knowledge scores (p=0.001) were significantly different at six weeks and six months after the initial training. Six weeks after the initial training session, the percentage of correct responses for knowledge questions was significantly higher than six months later. Approximately 86.3% of participants felt the BLS training was adequate to perform resuscitation confidently, while only 66.7% were confident after six months of training (p=0.001). Also, the number of students confident to give BLS during a medical emergency was significantly higher at six weeks after the initial training session than six months (p=0.001).

Conclusion: The study shows significant decay in psychomotor skills and knowledge and attitude among the medical undergraduates. Therefore, regular hands-on training with certifiable courses is required to reinforce skills and update knowledge regarding BLS.
Skip or captain?
Authors: Klopsch Britta , Gutbrod Johannes 
Published: September 2022

A changing world needs schools that adapt to changes and support their students to thrive. The related developments are moderated, guided, and also implemented by principals. To do this, they need the support of their staff, but also administrative support from the system. In Germany, the system's support is based on a link between management and leadership through clear task descriptions. The following text analyzes interviews with six school principals and their deputies who are actively engaged in school development for at least five years. It analyses how they deal to develop their schools on different levels.
It shows that two diametrically different types of leadership prevail in schools: The Captain and the Skip. Their role descriptions show that the underlying attitude contributes to empowering those involved for necessary change or restricting them in such a way that genuine, profound change is prevented. A shift in changing attitudes might therefore need open-minded principals and deputies who inspire hearts and minds and let change happen.
Características clínicas y análisis multivariado de los factores que inciden en la mortalidad en pacientes con cáncer de mama temprano
Authors: Ramos Guette Pedro Luis , Ramos Escalante Maria Athenas 
Published: September 2022

Objetivos: en Colombia este cáncer es primero en incidencia con 13.380 (14.01 %) casos nuevos y se presentaron 3.702 (8.79 %) muertes; corresponde a la tercera causa de mortalidad por cáncer. Objetivo principal: evaluar la supervivencia global de cáncer de mama temprano. Secundarios: 1. evaluar la supervivencia libre de enfermedad de cáncer de mama temprano; 2. evaluar los factores pronóstico para mortalidad en pacientes con cáncer de mama temprano. Materiales y métodos: este estudio realizó el análisis de información de la Clínica Oncocare en el periodo comprendido entre el 1° de enero de 2003 hasta el 31 de diciembre de 2019. Se incluyeron todos los pacientes de 18 o más años con diagnóstico de cáncer de mama temprano (estado I, IIA y IIB). Se construyeron curvas de supervivencia por el método de Kaplan-Meier; se compararon con el método de rangos logaritmos y se realizó un análisis de regresión de rangos proporcionales por Cox.
Desenlaces clínicos en una cohorte de pacientes con cáncer de amígdala entre 2015 y 2020 en la Fundación Santa Fe de Bogotá
Authors: Ospina Aylen Vanessa , Pino Villareal Luis Eduardo , Triana Avellaneda Iván Camilo , Segovia Javier Mauricio , Rubio Denisse 
Published: September 2022

Introducción: en Colombia no se dispone de datos suficientes y significativos sobre la caracterización del carcinoma de amígdala. Por esta razón, el propósito del presente estudio es describir una cohorte de pacientes de una institución local con disponibilidad de grupo multidisciplinar para el tratamiento del cáncer de cabeza y cuello. Materiales y métodos: estudio observacional descriptivo de una cohorte de pacientes con cáncer de amígdala, realizado desde agosto de 2015 hasta febrero de 2020. Se incluyeron variables clínicas y moleculares y los desenlaces clínicos respectivos. Se realizó un análisis descriptivo con reporte de frecuencias absolutas y posteriormente, se efectuó tanto un análisis de supervivencia mediante el método de Kaplan-Meier, como una comparación entre factores mediante un Log-rank Test con significancia menor a 0.05.
Características clínicas y supervivencia a largo plazo en pacientes con cáncer de mama pequeños T igual o menor a 2 cm y ganglios negativos
Authors: Ramos Guette Pedro Luis , Ramos Escalante Maria Athenas 
Published: September 2022

Objetivos: según la información de incidencias y mortalidad de Globocan del periodo 2018, el cáncer de mama es el nuevo segundo más frecuente en el mundo y el más frecuente en mujeres con un estimado de 2.088.849 (11.6 %) casos diagnosticados y es la quinta causa de muerte por cáncer (626 679 (6.6 %)). En Colombia es primero en incidencia con 13.380 (14.01 %) casos nuevos y se presentaron 3.702 (8.79 %) muertes, corresponde a la tercera causa de mortalidad por cáncer. General: describir la supervivencia global de las pacientes con cáncer de mama T1 menor o igual a 2 cm y ganglios negativos. Específicos: 1. describir la supervivencia libre de enfermedad de las pacientes con cáncer de mama T1 menor o igual a 2 cm y ganglios negativos; 2. describir las características clínicas y demográficas de las pacientes con cáncer de mama T1 menor o igual a 2 cm y ganglios negativos. Materiales y métodos: el diseño del estudio es observacional descriptivo retrospectivo basado en la información de la Clínica Oncocare en el periodo comprendido entre el 1° de enero de 2003 hasta el 31 diciembre de 2019. Se incluyeron todas las pacientes con diagnóstico de cáncer de mama T1 y ganglios negativos, se hace una descripción de las características clínicas y demográficas con estadística descriptiva medidas de tendencia central y dispersión, análisis exploratorio bivariado de algunas variables con relación a los desenlaces y se construyen curvas de supervivencia por el método Kaplan-Meier.
Características clínicas y demográficas en pacientes con cáncer de mama jóvenes de 40 años o menores
Authors: Ramos Guette Pedro Luis , Ramos Escalante Maria Athenas 
Published: September 2022

Objetivos: según la información de incidencias y mortalidad de Globocan del periodo 2018, el cáncer de mama es el nuevo segundo más frecuente en el mundo y el más frecuente en mujeres con un estimado de 2.088.849 (11.6 %) casos diagnosticados y es la quinta causa de muerte por cáncer (626 679 (6.6 %)). En Colombia es primero en incidencia con 13.380 (14.01 %) casos nuevos y se presentaron 3.702 (8.79 %) muertes; corresponde a la tercera causa de mortalidad por cáncer. General: describir la frecuencia de muertes en pacientes jóvenes con cáncer de mama. Específicos: 1. describir la frecuencia de recaídas de pacientes jóvenes con cáncer de mama; 2. describir las características clínicas y demográficas de pacientes jóvenes con cáncer de mama. Materiales y métodos: se realizó un estudio descriptivo retrospectivo con la información de la Clínica Oncocare en el periodo comprendido entre el 1° de enero de 2003 hasta el 31 diciembre de 2019. Se incluyeron todas las pacientes con diagnóstico de cáncer de mama jóvenes con edad de 40 años o menores. Se realizaron descripciones de las características clínicas y demográficas con estadística descriptiva, medidas de tendencia central y de dispersión; se construyeron curvas de supervivencia por método Kaplan-Meier. Resultados: un total de 79 pacientes fueron identificados en el estudio, la edad promedio fue 35.2 (rango 25-40), el estadio clínico se distribuyó así: I 4 (5.1 %), IIA 15 (18.9 %), IIB 18 (22.8 %), IIIA 25 (31.6%), IIIB 13 (16.5 %) y IIIC 4 (5.1 %), siendo el estadio avanzado 53.2 %; ganglios positivos en 64 (81.0%). Receptor hormonal positivo 55 (69.6 %), receptor Her 2 positivo 14 (17.7 %), grado histológico 2 y 3 58 (75.3 %), tamaño tumoral promedio 47mm. Recibieron quimioterapia neoadyuvante 65 (82.3%); los esquemas fueron antraciclinas 21 (32.3 %), antraciclinas y taxanos 28 (43.1 %), antraciclina más taxanos y antiher2 12 (18.5 %), no antraciclinas 4(6.1%); las respuestas patológicas completas fueron del 26.6 %.
Los matices de la sedación paliativa en oncología pediátrica : serie de casos
Authors: Molina Gómez Karen , García Quintero Ximena , Lotero Díaz Viviana 
Published: September 2022

Introducción y objetivos: la sedación paliativa (SP) se define como la administración deliberada de fármacos, en las dosis y combinaciones requeridas, para reducir la conciencia de un paciente con enfermedad avanzada o terminal tanto como sea necesario, con el fin de aliviar uno o más síntomas refractarios y con su consentimiento explícito o delegado. La SP tiene lugar para el manejo de síntomas refractarios o síntomas agudizados con alto grado de sufrimiento en el paciente. El objetivo del proyecto es realizar la descripción de una serie de casos de pacientes pediátricos oncológicos que requirieron uso de la sedación paliativa. Materiales y métodos: se realizó una revisión sistemática de literatura actualizada sobre la SP en niños. Se realizó una descripción de una serie de 3 casos del 2018 al 2020, que requirieron SP al final de vida. Resultados: Caso No. 1: escolar masculino, 6 años de edad, con ectomesenquimoma maligno en lóbulo frontal llevado a lobectomía más resección tumoral, 6 ciclos de quimioterapia y 30 sesiones de radioterapia. Dos meses después de terminar tratamiento, consulta por monoparesia de miembro superior derecho, vómito, anisocoria. La RNM cerebral reporta recaída de la enfermedad con lesiones supra e infratentoriales bilaterales, además, lesión extraaxial infiltrativa en columna cervical. No es candidato a cirugía. Se indica analgesia y esteroides. Reconsulta a la semana por deterioro neurológico, cefalea intensa y convulsiones, escala Lansky 20 %. Se da manejo sintomático, sin mejoría, se indica sedación inicialmente intermitente con midazolam y morfina. Presenta estatus convulsivo avanzando a sedación continua, que recibió por una semana.
Relationship between Toilet Training Initiation Age and Factors Affecting Toilet Training to Toilet Training Achievements
Authors: Meilisa Alya Nabila 
Published: September 2022

Abstrak: : Toilet training adalah suatu usaha untuk melatih anak agar mampu mengontrol buang air besar dan buang air kecil yang dipengaruhi oleh berbagai faktor. Tujuan penelitian: untuk mengetahui hubungan usia inisiasi toilet training dan faktor-faktor yang mempengaruhi toilet training dengan pencapaian toilet training. Metode: Penelitian ini merupakan penelitian yang bersifat kuantitatif berdesain penelitian deskriptif korelasional memakai pendekatan cross sectional. Sampel dalam penelitian ini adalah 100 responden yaitu orang tua yang mempunya anak prasekolah. Alat ukur yang digunakan adalah kuesioner yang disebarkan melalui google form terdiri dari 5 macam kuesioner yang telah dilakukan uji validitas dan reliabilitas. Hasil: Hasil penelitian menunjukkan bahwa tidak terdapat hubungan antara usia inisiasi toilet training (p value =0,297) dan pengetahuan orang tua (p value = 0,678) dengan pencapaian toilet training. Namun, terdapat hubungan antara peran orang tua (p value = 0,000) dan frekuensi penggunaan diapers (p value = 0,000) dengan pencapaian toilet training. Kesimpulan: usia inisiasi toilet training dan faktor pengetahuan orang tua tidak berhubungan dengan pencapaian toilet training sedangkan faktor peran orang tua dan frekuensi penggunaan diapers mempunyai hubungan yang bermakna dengan pencapaian toilet training.
GAMBARAN PENDAPAT KELUARGA ODGJ (ORANG DENGAN GANGGUAN JIWA) TENTANG PENYEBAB TERJADINYA GANGGUAN JIWA DAN PENGOBATANNYA PADA MASYARAKAT MELAYU DI KABUPATEN KEPULAUAN MERANTI
Authors: Wati Megawati 
Published: September 2022

ABSTRACT

Mental disorders are influenced by two factors that cause namely predisposing factors and precipitation factors. This study aims to describe the opinion of the family of ODGJ (People with Mental Disorders) about the causes of mental disorders and their treatment in the Malay community in the Meranti Islands. this study used a quantitative descriptive design. the results of the univariate analysis of the majority of respondents aged 17-25 years (late teens) (26.7%), the majority of respondents are female (80%), the majority of respondents have high school education (36.7%), the majority of respondents work as household workers (46.7%), genetic predisposing factors the majority of respondents have no family members who have mental disorders (86.7%), the majority of respondents have psychosocial disorders of rejection (28.6%), the majority of respondents have a history of unpleasant past experiences physical violence (23.5%), based on the type of treatment, most of the respondents took informal treatment (63.3%).
Keywords: Family Opinion, Causes of Mental Disorders, Seeking Treatment