bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does Adding Adverse Pregnancy Outcomes Improve the Framingham Cardiovascular Risk Score in Women? Data from the Tehran Lipid and Glucose Study
Authors: Saei Ghare Naz Marzieh , Sheidaei Ali , Aflatounian Ali , Azizi Fereidoun , Ramezani Tehrani Fahimeh 
Published: January 2022

Background
Limited and conflicting evidence is available regarding the predictive value of adding adverse pregnancy outcomes (APOs) to established cardiovascular disease (CVD) risk factors. Hence, the objective of this study was to determine whether adding APOs to the Framingham risk score improves the prediction of CVD events in women.

Methods and Results
Out of 5413 women who participated in the Tehran Lipid and Glucose Study, 4013 women met the eligibility criteria included for the present study. The exposure and the outcome variables were collected based on the standard protocol. Cox proportional hazard model was used to evaluate the association of APOs and CVDs. The variant of C‐statistic for survivals and reclassification of subjects into Framingham risk score categories after adding APOs was reported. Out of the 4013 eligible subjects, a total of 1484 (36.98%) women reported 1 APO, while 395 (9.84%) of the cases reported multiple APOs. Univariate proportional hazard Cox models showed the significant relations between CVD events and APOs. The enhanced model had a higher C‐statistic indicating more acceptable discrimination as well as a slight improvement in discrimination (C‐statistic differences: 0.0053). Moreover, we observed a greater risk of experiencing a CVD event in women with a history of multiple APOs compared with cases with only 1 APO (1 APO: hazard ratio [HR] = 1.22; 2 APOs: HR; 1.94; ≥3 APOs: HR = 2.48).

Conclusions
Beyond the established risk factors, re‐estimated CVDs risk by adding APOs to the Framingham risk score may improve the accurate risk estimation of CVD. Further observational studies are needed to confirm our findings.
It’s about time: Linking dynamical systems with human neuroimaging to understand the brain
Authors: John Yohan J. , Sawyer Kayle S. , Srinivasan Karthik , Müller Eli J. , Munn Brandon R. , Shine James M. 
Published: January 2022

Abstract
Most human neuroscience research to date has focused on statistical approaches that describe stationary patterns of localized neural activity or blood flow. While these patterns are often interpreted in light of dynamic, information-processing concepts, the static, local, and inferential nature of the statistical approach makes it challenging to directly link neuroimaging results to plausible underlying neural mechanisms. Here, we argue that dynamical systems theory provides the crucial mechanistic framework for characterizing both the brain’s time-varying quality and its partial stability in the face of perturbations, and hence, that this perspective can have a profound impact on the interpretation of human neuroimaging results and their relationship with behavior. After briefly reviewing some key terminology, we identify three key ways in which neuroimaging analyses can embrace a dynamical systems perspective: by shifting from a local to a more global perspective, by focusing on dynamics instead of static snapshots of neural activity, and by embracing modeling approaches that map neural dynamics using “forward” models. Through this approach, we envisage ample opportunities for neuroimaging researchers to enrich their understanding of the dynamic neural mechanisms that support a wide array of brain functions, both in health and in the setting of psychopathology.
Shapira’s Deuteronomy, Its Decalogue, and Dead Sea Scrolls Authentic and Forged
Authors: Klawans Jonathan 
Published: January 2022

Abstract
This essay engages Idan Dershowitz’s recent attempt to rehabilitate the Deuteronomy fragments Moses Wilhelm Shapira offered for sale in 1883. After summarizing the contents of Dershowitz’s volume, this paper evaluates Shapira’s fragments in relation to the Dead Sea Scrolls, the Moabitica and other forgeries connected to Shapira. It considers the implications of Shapira’s transcription of the text, which Dershowitz uses to demonstrate Shapira’s innocence. To counter Dershowitz’s hypothesis regarding the “proto-biblical” origin of the fragments, it is proposed that the composition is better understood as a post-biblical pastiche. Dershowitz has endeavored to sever the text from the possibilities allowed by 19th century European scholarship; the present article contextualizes the find within the religious world of 19th century Jerusalem. While the allure of significance can encourage scholars to overcome doubts and accept the authenticity of suspicious objects, Shapira’s fragments remain very dubious indeed.
Factors Underlying Return Migration Decisions among Nigerian Victims of 2019 Xenophobic Violence in South Africa
Authors: Tade Oludayo 
Published: January 2022

Abstract
Studies on xenophobic violence have mainly focused on their causes and effects, but have yet to probe how victimisation experiences of xenophobia trigger migration intentions and actual practices. In a balance of tales, I examine how families contributed to staying put/return decisions by Nigerian migrants in South Africa following the September 2019 xenophobic violence. The study asks: to what extent do family facilitate and/or contribute to the decision to return? And how do return strategies unveil the centrality of family in taking migration decisions? Data emerged through online interviews with Nigerian immigrants in South Africa who stayed put, and six family members in Nigeria were reached through snowball sampling. This was supplemented with secondary interviews conducted with Nigerian returnees in three National newspapers (The Punch, Vanguard, Nigerian Tribune and The Nation newspapers). Findings show the centrality of family in both migration intentions, staying-put, and the actual practices of Nigerian victims of xenophobia in South Africa.
Human Resilience in the Face of Mid-Holocene Climate Change on the Central West Coast of South Africa
Authors: Jerardino Antonieta 
Published: January 2022

Abstract
After the Last Glacial Maximum, important yet milder climatic trends continued to characterise the Holocene. None of them was more challenging to forager groups in the central west coast of South Africa than the mid-Holocene Altithermal (8200–4200 cal BP). Hot and dry weather and 1–3 m higher sea levels were thought once to have barred local foragers from this region because of a lack of sites dating to this period. Instead, this initial scenario reflected largely a sampling problem. Steenbokfontein Cave is one of a few sites with some of the largest mid-Holocene deposits, allowing insights into forager adaptations during this period. Results show high mobility over large distances and a terrestrial diet mostly dependant on small bovids, complemented with fewer coastal resources. Stone tool kits and lithic raw materials among various sites suggest that much evidence for mid-Holocene occupation is actually found near the local riparian systems.
Recent Changes in Average Recurrence Interval Precipitation Extremes in the Mid-Atlantic United States
Authors: DeGaetano Arthur T. , Tran Harrison 
Published: January 2022

AbstractIncreases in the frequency of extreme rainfall occurrence have emerged as one of the more consistent climate trends in recent decades, particularly in the eastern United States. Such changes challenge the veracity of the conventional assumption of stationarity that has been applied in the published extreme rainfall analyses that are the foundation for engineering design assessments and resiliency planning. Using partial-duration series with varying record lengths, temporal changes in daily and hourly rainfall extremes corresponding to average annual recurrence probabilities ranging from 50% (i.e., the 2-yr storm) to 1% (i.e., the 100-yr storm) are evaluated. From 2000 through 2019, extreme rainfall amounts across a range of durations and recurrence probabilities have increased at 75% of the long-term precipitation observation stations in the mid-Atlantic region. At approximately one-quarter of the stations, increases in extreme rainfall have exceeded 5% from 2000 through 2019, with some stations experiencing increases in excess of 10% for both daily and hourly durations. At over 40% of the stations, the rainfall extremes based on the 1950–99 partial-duration series show a significant (p> 0.90) change in the 100-yr ARI relative to the 1950–2019 period. Collectively, the results indicate that, given recent trends in extreme rainfall, routine updates of extreme rainfall analyses are warranted on 20-yr intervals.Significance StatementEngineering design standards for drainage systems, dams, and other infrastructure rely on analyses of precipitation extremes. Often such structures are designed on the basis of the probability of exceeding a specified rainfall rate in a given year. The frequency of extreme rainfall events has increased in the mid-Atlantic region of the United States in recent decades, leading us to evaluate how these changes have affected these exceedance probabilities. From 2000 through 2019, there has been a consistent increase of generally 2.5%–5.0% in design rainfall amounts. The increase is similar across a range of rainfall durations from 1 h to 20 days and also annual exceedance probabilities ranging from 50% to 1% (i.e., from the “2-yr storm” to the “100-yr storm”). The work highlights the need to routinely update the climatological extreme-value analyses used in engineering design, with the results suggesting that a 20-yr cycle might be an appropriate update frequency.
The Effect of Wind Stress on Seasonal Sea-Level Change on the Northwestern European Shelf
Authors: Hermans Tim H. J. , Katsman Caroline A. , Camargo Carolina M. L. , Garner Gregory G. , Kopp Robert E. , Slangen Aimée B. A. 
Published: January 2022

AbstractProjections of relative sea level change (RSLC) are commonly reported at an annual mean basis. The seasonality of RSLC is often not considered, even though it may modulate the impacts of annual mean RSLC. Here, we study seasonal differences in twenty-first-century ocean dynamic sea level change (DSLC; 2081–2100 minus 1995–2014) on the Northwestern European Shelf (NWES) and their drivers, using an ensemble of 33 CMIP6 models complemented with experiments performed with a regional ocean model. For the high-end emissions scenario SSP5–8.5, we find substantial seasonal differences in ensemble mean DSLC, especially in the southeastern North Sea. For example, at Esbjerg (Denmark), winter mean DSLC is on average 8.4 cm higher than summer mean DSLC. Along all coasts on the NWES, DSLC is higher in winter and spring than in summer and autumn. For the low-end emissions scenario SSP1–2.6, these seasonal differences are smaller. Our experiments indicate that the changes in winter and summer sea level anomalies are mainly driven by regional changes in wind stress anomalies, which are generally southwesterly and east-northeasterly over the NWES, respectively. In spring and autumn, regional wind stress changes play a smaller role. We also show that CMIP6 models not resolving currents through the English Channel cannot accurately simulate the effect of seasonal wind stress changes on the NWES. Our results imply that using projections of annual mean RSLC may underestimate the projected changes in extreme coastal sea levels in spring and winter. Additionally, changes in the seasonal sea level cycle may affect groundwater dynamics and the inundation characteristics of intertidal ecosystems.
The Multigrid Beta Function Approach for Modeling of Background Error Covariance in the Real-Time Mesoscale Analysis (RTMA)
Authors: Purser R. James , Rancic Miodrag , Pondeca Manuel S. F. V. De 
Published: January 2022

Abstract
We describe a method for the efficient generation of the covariance operators of a variational data assimilation scheme, which is suited to implementation on a massively parallel computer. The elementary components of this scheme are what we call “beta filters,” since they are based on the same spatial profiles possessed by the symmetric beta distributions of probability theory. These approximately Gaussian (bell-shaped) polynomials blend smoothly to zero at the ends of finite intervals, which makes them better suited to parallelization than the present quasi-Gaussian “recursive filters” used in operations at NCEP. These basic elements are further combined at a hierarchy of different spatial scales into an overall multigrid structure formulated to preserve the necessary self-adjoint attribute possessed by any valid covariance operator. This paper describes the underlying idea of the beta filter and discusses how generalized Helmholtz operators can be enlisted to weight the elementary contributions additively in such a way that the covariance operators may exhibit realistic negative sidelobes, which are not easily obtained through the recursive filter paradigm. The main focus of the paper is on the basic logistics of the multigrid structure by which more general covariance forms are synthesized from the basic quasi-Gaussian elements. We describe several ideas on how best to organize computation, which led us to a generalization of this structure that made it practical so that it can efficiently perform with any rectangular arrangement of processing elements. Some simple idealized examples of the applications of these ideas are given.
Using a Cost-Effective Approach to Increase Background Ensemble Member Size within the GSI-Based EnVar System for Improved Radar Analyses and Forecasts of Convective Systems
Authors: Gasperoni Nicholas A. , Wang Xuguang , Wang Yongming 
Published: January 2022

Abstract
A valid time shifting (VTS) method is explored for the GSI-based ensemble variational (EnVar) system modified to directly assimilate radar reflectivity at convective scales. VTS is a cost-efficient method to increase ensemble size by including subensembles before and after the central analysis time. Additionally, VTS addresses common time and phase model error uncertainties within the ensemble. VTS is examined here for assimilating radar reflectivity in a continuous hourly analysis system for a case study of 1–2 May 2019. The VTS implementation is compared against a 36-member control experiment (ENS-36), to increase ensemble size (3 × 36 VTS), and as a cost-savings method (3 × 12 VTS), with time-shifting intervals τ between 15 and 120 min. The 3 × 36 VTS experiments increased the ensemble spread, with largest subjective benefits in early cycle analyses during convective development. The 3 × 12 VTS experiments captured analysis with similar accuracy as ENS-36 by the third hourly analysis. Control forecasts launched from hourly EnVar analyses show significant skill increases in 1-h precipitation over ENS-36 out to hour 12 for 3 × 36 VTS experiments, subjectively attributable to more accurate placement of the convective line. For 3 × 12 VTS, experiments with τ ≥ 60 min met and exceeded the skill of ENS-36 out to forecast hour 15, with VTS-3 × 12τ90 maximizing skill. Sensitivity results demonstrate preference to τ = 30–60 min for 3 × 36 VTS and 60–120 min for 3 × 12 VTS. The best 3 × 36 VTS experiments add a computational cost of 45%–67%, compared to the near tripling of costs when directly increasing ensemble size, while best 3 × 12 VTS experiments save about 24%–41% costs over ENS-36.

Significance Statement
The purpose of this work is to study a valid time shifting method to improve the prediction of severe convective storm systems over the continental United States. This method improves ensemble-based radar reflectivity analyses by including ensemble member information at times before and after the analysis time, thereby increasing the ensemble size at just a fractional added computational cost. The results show the method can boost the accuracy of high-resolution convection prediction out to at least 12 h. This case study motivates future systematic testing in a real-time setting and potential implementation to enhance the U.S. operational ensemble-based convection-allowing forecast model and data assimilation system.
Expanding PrEP Services for Men Who Have Sex With Men and Transgender Persons Through Health Department Programs: Key Processes and Outcomes From Project PrIDE, 2015-2019
Authors: Mulatu Mesfin S. , Carter Jarvis W. , Flores Stephen A. , Benton Shaliondel , Galindo Carla A. , Johnson Wayne D. , Wilkes Aisha L. , Prather Cynthia 
Published: January 2022

Objective: Pre-exposure prophylaxis (PrEP) Implementation, Data to Care, and Evaluation (PrIDE) was a demonstration project implemented by 12 state and local health departments during 2015-2019 to expand PrEP services for men who have sex with men (MSM) and transgender persons at risk for HIV infection. We describe findings from the cross-jurisdictional evaluation of the project. Methods: We analyzed work plans, annual progress reports, and aggregate quantitative program data submitted by funded health departments (n = 12) to identify key activities implemented and summarize key project outcomes. Results: PrIDE jurisdictions implemented multiple health equity–focused activities to expand PrEP services to priority populations, including building program capacity, conducting knowledge and awareness campaigns, providing PrEP support services, and addressing barriers to PrEP use. Overall, PrIDE jurisdictions identified 44 813 persons with PrEP indications. Of these, 74.8% (n = 33 500) were referred and 33.1% (n = 14 821) were linked to PrEP providers, and 25.3% (n = 11 356) were prescribed PrEP. Most persons prescribed PrEP were MSM or transgender persons (87.9%) and persons from racial and ethnic minority groups (65.6%). However, among persons with PrEP indications, non-Hispanic Black/African American persons (14.9% of 18 782) were less likely than non-Hispanic White persons (31.0% of 11 633) to be prescribed PrEP ( z = −33.57; P < .001). Conclusions: PrIDE jurisdictions successfully expanded PrEP services for MSM, transgender persons, and racial and ethnic minority groups by implementing health equity–focused activities that addressed barriers to PrEP services. However, PrEP prescription was generally low, with significant disparities by demographic characteristics. Additional targeted interventions are needed to expand PrEP services, achieve equity in PrEP use, and contribute to ending the HIV epidemic in the United States.
Social Mobility of Puerto Ricans
Authors: Kantrowitz Nathan 
Published: January 2022

Upward mobility is possible to an immigrant group if the institutions of the host society are open to social change and the immigrants’ culture encourages social mobility. The Author tests his assumption by analyzing the Census statistics of 1950 and 1960 for the New York metropolis concerning Puerto Ricans. The conclusion is that in New York between 1950 and 1960 the children of Puerto Rican migrants, at least, were upwardly mobile: they attained some high school education, certain white collar jobs, and, to a lesser extent, higher income. Puerto Rican parents, however, are stil poor, and so are their childen. But if the experience of the decade studied can be a basis for prediction, the possibility of achieving a social class distribution similar to that of other groups in the city is very real for the Puerto Rican migrants in their own remaining life spans and those of their children. The article examines one metropolitan area. Its finding corroborate those discussed by John J. Macisco, Jr. regarding mobility patterns of the Pueto Ricans in the total United States mainland.
Southern Europeans in Australia: Problems of Assimilation
Authors: Price Charles 
Published: January 2022

The search for a clearer definition of the concept and the social implications of immigrants’ integration is constantly renewed. Price extends his analysis to a number of different variables affecting and measuring integration or assimilation, including: urban concentration, the role of the ethnic community, intermarriages, political involvement, the important function of the churches, and intergenerational conflict. The experience of America is often compared with that of Australia. Although non-British ethnic groups make up only 20 percent of the Australia population, a one type melting pot seems impossible. Rather, the Author observes that some groupings are emerging according to religious affiliation. Nobody, however, can predict the exact period of time needed for total integration and the process will probably cover several generations.
Three Generations of Italians in New York City: Their Religious Acculturation
Authors: Russo Nicholas John 
Published: January 2022

Renewed awareness in ethnic groups as well identified, persisting and active participants in the political and social life of American society imposes a new task on the social scientists to define better and more cogently measure the implications of pluralism and integration. This article by Russo—presenting the findings of his doctoral dissertation: The Religious Acculturation of the Italians in New York City—evidences the fast disappearance of the cultural identity of an immigrant group in relation to their rural religious tradition and behavior. At the same time, it notes the survival of social identity. In the light of this evidence, we can ask ourselves if ethnic religious institutions might have led the immigrants to religious forms more in keeping with their new environment and how the acculturation described should be evaluated. Above all, we are forced to search for those variables which maintain the ethnic groups’ identity even in the third generation. In this way, the process of the inclusion into American society of different ethnic and religious groups may reveal some clues for the more complex test of inclusion of different racial groups.
A systematic review of current trends in pharmacologic management after stent placement in nonthrombotic iliac vein lesions
Authors: Veyg Daniel , Alam Mustafa , Yelkin Henry , Dovlatyan Ruben , DiBenedetto Laura , Ting Windsor 
Published: January 2022

Objective Stenting of the iliac vein is increasingly recognized as a treatment for chronic venous insufficiency (CVI). However, the pharmacologic management after stent placement is unclear. This review was conducted to illustrate recent trends in anticoagulation and antiplatelet regimens following stent placement for nonthrombotic iliac vein lesions (NIVL). Methods The MEDLINE database was searched using the term “iliac vein stent.” Retrieval of articles was limited to studies conducted on humans and published in English between 2010 and 2020. Studies were included that described iliac vein stent placement. Studies were excluded that contained fewer than 25 patients, performed procedures other than stent placement, did not specify the postoperative anticoagulant used, or treated lesions of thrombotic origin. Results 12 articles were included in this review, yielding a total of 2782 patients with a male-to-female ratio of 0.77. The predominant CEAP classification encountered was C3. The most common stent used in the included studies was the Wallstent (9/12), and the most common pharmacologic regimen was 3 months of clopidogrel (6/12). Warfarin, aspirin, cilostazol, and rivaroxaban were among other agents used. Primary stent patency ranged from 63.1 to 98.3%. There was no apparent correlation between pharmacologic agent used and stent patency or subjective patient outcomes. Conclusion Multiple different approaches are being taken to pharmacologically manage patients following stent placement for NIVL. There is no consensus on which agent is best, nor is there a formal algorithmic approach for making this decision. Additionally, the findings in this study call into question whether anticoagulation following stenting for NIVL is necessary at all, given the similar outcomes among the different agents utilized. This review underscores the potential value of undertaking a multi-institutional prospective study to determine what is the best pharmacologic therapy following venous stent placement for NIVL.