bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of retraction efficacy of titanium-molybdenum and titanium-niobium alloy wires – A prospective split-mouth study
Authors: Jain Nikhil , Vichare Gauri , Bhosale Veera 
Published: September 2022

Objectives:
The study aimed to compare the efficacy of Titanium-Molybdenum (Ti-Mo) and Titanium-Niobium (Ti-Nb) alloy wires as retraction springs, by comparing: The amount and rate of canine retraction, the degree of canine rotation, the change in axial inclination of canines, and the associated anchorage loss.

Material and Methods:
All 17 participants (age: 18–25 years) to be treated with the first premolar extraction approach by canine retraction were assigned Ti-Mo and Ti-Nb alloy T-loop springs to either of the upper quadrants randomly. Digital intraoral 3-D scans and panoramic radiographs orthopantomagram (OPG) were taken before (T0) and after (T1) the study period (4 months). 3-D superimposition was performed and using the digital models and OPG, changes in canine position, angulation, and anchorage loss were compared between the two groups.

Results:
There was no significant difference between the two treatment groups for all the parameters pertaining to maxillary canine retraction, that is, canine retraction (P = 0.72), change in axial inclination of canines (P = 0.71), rotation of canines (P = 0.74), and anchorage loss (P = 0.13) as well as extraction space closure (P = 0.74).

Conclusion:
Ti-Nb and Ti-Mo alloy wires show a similar potency for use in retraction mechanics for orthodontic space closure.
Bibliometric analysis of research publications in three major orthodontic journals during 2012–2021
Authors: Li Jiachen , Onsiong Kimberlee , Cheung Elok Yi Lok , Lin Yifan 
Published: September 2022

Objectives:
This study conducted a comprehensive bibliometric analysis of articles published from 2012 to 2021 in three orthodontic journals: The American Journal of Orthodontics and Dentofacial Orthopedics (AJODO), The Angle Orthodontist (AO), and European Journal of Orthodontics (EJO).

Material and Methods:
Eligible articles published from 2012 to 2021 in AJODO, AO, and EJO were retrieved from the Web of Science Core Collection database and subsequently processed using CiteSpace software to generate their characteristics, including authorship, institution, geographic origin, keywords, and citation profiles.

Results:
The three orthodontic journals published 4001 articles from 370 institutions in 95 countries from 2012 to 2021. The AJODO published the most articles (45.5%) followed by AO (31.3%) and EJO (23.2%). The most prolific country was the United States (US), followed by Brazil, South Korea, China, and Turkey. The authors from the US were heavily engaged in international collaborations, especially with South Korea and Brazil. The country and institutions with the highest citation counts per publication were Italy and the University of Bern (Switzerland), respectively. Pandis N was the most prolific author, and Proffit W was the most-cited author in the 4001 publications. The keywords that emerged most frequently were “children” followed by “orthodontic treatment” and “malocclusion.” Four of the 10 most-cited articles were related to digital dental technology.

Conclusion:
This bibliometric analysis provides a complete picture of the research published in three major orthodontic journals over the past decade. It comprehensively analyzes the authorship, country of origin, institutions, keywords, and citation profiles of the articles.
Success rate of mini-implants based on side of insertion and type of jaw in adult patients undergoing orthodontic treatment – A systematic review and meta-analysis
Authors: Devadkar Rutuja Sheshnarayan , Potnis Sheetal , Toshniwal Nandalal , Pharande Shilpa , Vinay Vineet 
Published: September 2022

Objectives:
To find out success rate of mini-implants based on side of insertion and type of jaw. The aim of orthodontic treatment is to maintain sufficient anchorage control to create appropriate force systems that provide the desired treatment effects. Implants have been used as skeletal anchorage devices for orthodontic purposes.

Material and Methods:
The following study is a systematic review of mini-screws as an intervention to evaluate the stability and different related clinical parameters to define the success rate (outcome) depending on the side of insertion (i.e., right side and left side) and type of jaw (i.e., maxilla and mandible following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses).

Results and Conclusion:
A total of 52 articles were extracted for qualitative synthesis among which 24 articles were reviewed for meta-analysis and the results showed that the maxilla is a better placement site for insertion of mini-implant (MI) than mandible with the odds ratio of 0.58, that is, the MI placement in the maxillary region is 58% more successful than mandibular region. The other parameter showed that the insertion of MI on the right side was more successful with the odds ratio of 0.50, that is, the insertion of MI on the right side of the jaw is 50% more successful than on the left side of the jaw.
Konstruksi Sosial Tradisi Kebur Ubalan Pada Masyarakat Kabupaten Kediri
Authors: Retnaning Ida , Ruja I Nyoman 
Published: September 2022

Tujuan penelitian dari tradisi Kebur Ubalan adalah mengetahui konstruksi sosial kepala keluarga terkait dengan tradisi Kebur Ubalan dan menganalisis makna simbolik dalam kegiatan tradisi Kebur Ubalan. Metode penelitian yang digunakan adalah metode kualitatif dengan pendekatan etnografi. Penelitian ini dilakukan di Desa Jarak, Kecamatan Plosoklaten, Kabupaten Kediri. Teknik pengumpulan data dilakukan dengan observasi, wawancara, dan studi dokumen. Teknik analisis data dilakukan dengan reduksi, interpretasi, dan penarikan kesimpulan. Hasil penelitian ini menunjukan bahwa dalam tradisi Kebur Ubalan, kepala keluarga memiliki andil yang cukup besar pada saat tradisi berlangsung. Tradisi Kebur Ubalan yang memiliki arti saling siram air pada sebuah mata air untuk meminta hujan pada saat musim kemarau. Makna simbolik tradisi Kebur Ubalan adalah sebagai perwujudan rasa syukur atas panen yang melimpah, bergotong royong, toleransi antar umat beragama dan tetap melestarikan budaya.
ESTIMATION OF THIRD FINGER MOTION USING ENSEMBLE KALMAN FILTER
Authors: Herlambang Teguh , Nurhadi Hendro , Muhith Abdul , Rahmalia Dinita , Tomasouw Berny Pebo 
Published: September 2022

Post-stroke is a stage a patient undergoes if the patient has had a previous stroke. Stroke is a big and serious problem. As the second most common cause of disability of people at age of over 60 years. For patients having experienced a stroke, rehabilitation is a way to make them able to do activities of daily living as before. Stroke Rehabilitation is a comprehensive medical management and rehabilitation (in medical, emotional, social, and vocational aspects) concerning disabilities caused by stroke through a neuro-rehabilitation approach with the aim of optimizing recovery. The finger prosthetic arm robot is one of the results of the health technology development to help accelerate the rehabilitation process specifically for finger movements. One of the efforts to develop a finger robot is to estimate the movement of the fingers, in this case the finger size used is taken from those of Javanese people in Indonesia as the data to be simulated. In this paper is an estimation of the finger motion,particularly that of the third finger of the right hand, conducted using the Ensemble Kalman Filter (EnKF) method. The simulation results produced the third finger motion estimates with an accuracy of around 92% - 99%.
Mapeando Celso Pereira De Sá: Itinerários De Sua Atividade Intelectual (1970-1990)
Authors: Garcia Alves Roberta , Lopes Miranda Rodrigo 
Published: September 2022

Esta proposta se caracteriza como uma pesquisa histórico-conceitual que objetivou identificar as produções de Celso Pereira de Sá vinculadas Análise do Comportamentoàe interpretar as redes conceituais e filosóficas contidas nestes trabalhos, relacionando-as com elementos historiográficos de sua atividade intelectual entre 1970 a 1990. O percurso metodológico foi organizado em duas dimensões; uma historiográfica a qual se utilizou da análise documental e outra conceitual a qual se utilizou do software Iramuteq e de apropriações de estratégias do Procedimento de Interpretação Contextual de Texto (PICT). Encontramos um autor refletindo sobre o papel do intelectual e da produção de conhecimento científico para a resolução de problemas sociais eminentemente brasileiros. Sá investiu na educação política popular no qual a população teria ela própria condições de produzir conhecimento sobre sua realidade e nela intervir. Seu conceito de comportamento baseia-se no entendimento de que o sujeito é necessariamente um ser histórico, social e verbal. Além disso, o conceito de contracontrole social indica uma transformação na sociedade, salientando o papel do comportamento verbal como veículo potencializador na mobilização para a transformação social.
Из истории «Известий» Комитета петроградских журналистов (27 февраля – 5 марта 1917 года)
Authors: Николаев (Andrei Borisovich Nikolae Андрей Борисович 
Published: September 2022

Абстракт
Организация Комитета петроградских журналистов стала началом прорыва информационной блокады Февральской революции. Комитет создал «Известия», первый номер которых вышел вечером 27 февраля в типографии Товарищества А. С. Суворина – «Новое время». Всего с 27 февраля и по 5 марта 1917 г. вклю- чительно вышло 10 номеров. В зависимости от места издания (печатались в 7 типографиях) «Известия» имели разное оформление, отличались по содер- жанию. Таким образом, можно говорить о 46 выпусках и 7 редакциях издания «Известий». Созданные благодаря поддержке как со стороны Временного коми- тета Государственной думы, так и Временного Исполкома Петроградского Совета рабочих депутатов, «Известия» фактически стали органом думского Комитета.
Эстонская историография императорского Дерптского/Юрьевского университета
Authors: Шор (Tatjana Shor) Татьяна 
Published: September 2022

Abstract
В статье рассматриваются историографические опыты эстонских ученых, изуча- ющих историю императорского Дерптского/Юрьевского университета с различ- ных идеологических и методологических позиций. В фокусе как традиционная юбилейная литература общего характера, так и работы советских и постсовет- ских историков.
A brief history of Canadian freeze-dried blood products: Ingenuity, collaboration, and leadership
Authors: Moore Marcus A. , Beckett Andrew 
Published: September 2022

LAY SUMMARY During the Second World War, Canada became a leader in the development and production of products used to treat shock, particularly shock caused by massive bleeds. Canada started the first blood service in response to the need for blood products overseas. This was done in the form of freeze-dried serum, which is made up of fluid-based proteins extracted from blood. Freeze-dried serum could be stored indefinitely and was lightweight, hardy, and easy to deliver both to the battlefield and to the patient. Freeze-dried serum could be provided to patients in shock as a result of losing a large volume of blood. Unfortunately, after the war, freeze-dried blood products fell out of favour over concerns about viral hepatitis. Recently, freeze-dried blood products have enjoyed a renaissance, and Canada is currently developing a new product to meet the challenges of remote resuscitation.
Quaternary volcanism in the Yura Monogenetic Field near Arequipa city, southern Peru
Authors: Aguilar Rigoberto , Arteaga David , Manrique Nélida , van Wyk de Vries Benjamin , Cueva Kevin , Taipe Edu , Guillou Hervé , Scao Vincent 
Published: September 2022

Arequipa (Peru) is an area where volcanic activity has been persistent during the Quaternary. Studies carried out in this area have highlighted the emplacement of ignimbrite deposits, large volcanic clusters and stratovolcanoes. Monogenetic volcanism is also present, although poorly explored and studied. Due to its location over an ignimbrite plain and poor state of preservation, the only identified monogenetic cone in the Arequipa basin was the Nicholson volcano, while other monogenetic centers remained unknown. This lack of information about the recent volcanism can lead to inadequate definition of scenarios in a hazard assessment in the region. The present study has investigated monogenetic volcanism in the northwestern edge of the Arequipa basin based on geological survey, geochronology and geochemical data. Here, we report for the first time five small volcanic centers such as Yura Viejo, Ccapua, Uyupampa, El Chiral and Patacocha, which together with the Nicholson volcano form the Yura Monogenetic Field. Stratigraphic considerations and new 40Ar/39Ar ages allow us to place the eruptive activity in the Middle–Upper Pleistocene (c. 195–54 ka). Phreatomagmatic, Strombolian and effusive eruptions characterize the monogenetic activity of the field. As a result of these eruptions, small scoria cones, maars, and lava flows/coulées were generated. The eruptive products show ubiquitous olivine phenocryst-rich (&lt;10 vol%) set in a fine pilotaxitic groundmass, suggesting rapid ascent of basaltic magmas to the surface controlled by the tectonic setting. The analyzed rocks lie in a narrow range of basaltic-andesite composition (50.9–55.6 wt% SiO2) being the most mafic Pleistocene - Recent volcanic products identified in the Arequipa basin, along with the least differentiated magmas from the nearby Chachani volcanic cluster. This work shows how monogenetic volcanism can occur contemporaneous and closely spaced to larger volcanic clusters and active stratovolcanoes. We hope the information provided here will contribute to improve the risk management by highlighting the scenario of monogenetic eruptions that should be considered in the hazard assessment.
Probabilistic geothermal resource assessment in Maichen Sag, south China
Authors: Wang Mingchuan , Yang Fan , Zhang Ying , Zhang Dianwei , Feng Jianyun , Luo Jun , Zeng Yan 
Published: September 2022

It is crucial for financial providers, investment groups, resource developers, and exploration companies to rate new geothermal projects in terms of resources and reserves. In general, the existing volumetric method is constrained by limited information when projects are at the early stage of development. The main objective of this study is to estimate the probabilistic potential thermal energy of the M research area in the Maichen Sag, a geothermal prospect in South China, through stochastic methodologies. The probabilistic assessment methodology provides a way to embody the uncertainty and risk in geothermal projects and to quantify the power potential in a probable range. In this study, proxy numerical models were built by combining the Experimental Design (ED) and Response Surface Methodology (RSM) with the Monte Carlo Simulation technique. An improved workflow for combined ED-RSM that uses two-level Full Factorial and Box–Behnken designs was proposed. For comparative analysis, the typical volumetric technique was also implemented in this study. The ED-RSM results show that the M area has P10, P50, and P90 reserves of 5.7 × 1014 J, 5.3 × 1014 J, and 5 × 1014 J, respectively, and these numbers from the typical volumetric method are 1.5 × 1015 J, 9 × 1014 J, and 5.1 × 1014 J, respectively. In this study, the operability, applicability, and accessibility of ED-RSM in the assessment of geothermal potential and its ability to provide a reliable output are demonstrated.
Integration of three machine learning algorithms identifies characteristic RNA binding proteins linked with diagnosis, immunity and pyroptosis of IgA nephropathy
Authors: Zhang Xueqin , Chao Peng , Jiang Hong , Yang Shufen , Muhetaer Gulimire , Zhang Jun , Song Xue , Lu Chen 
Published: September 2022

Objective: RNA-binding proteins (RBPs) are essential for most post-transcriptional regulatory events, which exert critical roles in nearly all aspects of cell biology. Here, characteristic RBPs of IgA nephropathy were determined with multiple machine learning algorithms.Methods: Our study included three gene expression datasets of IgA nephropathy (GSE37460, GSE73953, GSE93798). Differential expression of RBPs between IgA nephropathy and normal samples was analyzed via limma, and hub RBPs were determined through MCODE. Afterwards, three machine learning algorithms (LASSO, SVM-RFE, random forest) were integrated to determine characteristic RBPs, which were verified in the Nephroseq database. Immune cell infiltrations were estimated through CIBERSORT. Utilizing ConsensusClusterPlus, IgA nephropathy were classified based on hub RBPs. The potential upstream miRNAs were predicted.Results: Among 388 RBPs with differential expression, 43 hub RBPs were determined. After integration of three machine learning algorithms, three characteristic RBPs were finally identified (DDX27, RCL1, and TFB2M). All of them were down-regulated in IgA nephropathy than normal specimens, with the excellent diagnostic efficacy. Additionally, they were significantly linked to immune cell infiltrations, immune checkpoints, and pyroptosis-relevant genes. Based on hub RBPs, IgA nephropathy was stably classified as two subtypes (cluster 1 and 2). Cluster 1 exhibited the relatively high expression of pyroptosis-relevant genes and characteristic RBPs. MiR-501-3p, miR-760, miR-502-3p, miR-1224-5p, and miR-107 were potential upstream miRNAs of hub RBPs.Conclusion: Collectively, our findings determine three characteristic RBPs in IgA nephropathy and two RBPs-based subtypes, and thus provide a certain basis for further research on the diagnosis and pathogenesis of IgA nephropathy.
HRD-MILN: Accurately estimate tumor homologous recombination deficiency status from targeted panel sequencing data
Authors: Wang Xuwen , Xu Ying , Zhang Yinbin , Wang Shenjie , Zhang Xuanping , Yi Xin , Zhang Shuqun , Wang Jiayin 
Published: September 2022

Homologous recombination deficiency (HRD) is a critical feature guiding drug and treatment selection, mainly for ovarian and breast cancers. As it cannot be directly observed, HRD status is estimated on a small set of genomic instability features from sequencing data. The existing methods often perform poorly when handling targeted panel sequencing data; however, the targeted panel is the most popular sequencing strategy in clinical practices. Thus, we proposed HRD-MILN to overcome the computational challenges from targeted panel sequencing. HRD-MILN incorporated a multi-instance learning framework to discover as many loss of heterozygosity (LOH) associated with HRD status to cluster as possible. Then the HRD score is obtained based on the association between the LOHs and the cluster in the sample to be estimated, and finally, the HRD status is estimated based on the score.In comparison experiments on targeted panel sequencing data, the Precision of HRD-MILN could achieve 87%, significantly improved from 63% reported by the existing methods, where the highest margin of improvement reached 14%. It also presented advantages on whole exome sequencing data. Based on our best knowledge, HRD-MILN is the first practical tool for estimating HRD status from targeted panel sequencing data and could benefit clinical applications.
A poor perspective of self weight significantly increases adverse outcomes in non-alcoholic fatty liver disease (NAFLD)
Authors: Fu Clarissa Elysia , Ng Cheng Han , Chew Nicholas W. S. , Heng Zane En Qi , Chin Yip Han , Quek Jingxuan , Lim Wen Hui , Xiao Jieling , Chan Kai En , Tan Darren Jun Hao , Tan Caitlyn , Zhang Sitong , Koh Teng Kiat , Nah Benjamin , Dan Yock Young , Syn Nicholas , Siddiqui Mohammad Shadab , Sanyal Arun J. , Noureddin Mazen , Muthiah Mark 
Published: September 2022

BackgroundNon-alcoholic fatty liver disease (NAFLD) is prevalent amongst overweight and obese individuals, and weight loss remains the main mode of treatment for NAFLD patients. Weight perception plays a key role in the efficacy of such treatment. The current study aims to investigate the prevalence, associating factors and implications of poor weight perception amongst such individuals.MethodsAn analysis was done on data collected from NHANES between 1999 and 2018. Comparison was made between NAFLD individuals with and without poor weight perception in terms of prevalence, associated characteristics, and clinical outcomes. Multivariate analysis was used to compare effect size of adverse events associated with NAFLD individuals with poor weight perception.ResultsOf the 12,170 NAFLD patients, 19.2% (CI: 18.5 to 19.9%) had poor weight perception. Poor weight perception was significantly associated with lower education levels, reduced levels of exercise and unhealthier lipid profiles. There was an increased risk in all-cause mortality (HR: 1.18, CI: 1.00 to 1.38, p = 0.047), cardiovascular disease mortality (SHR: 1.33, CI: 1.03 to 1.71, p = 0.026), major adverse cardiovascular events (OR: 1.21 CI: 1.10 to 1.32, p &lt; 0.001), and advanced fibrosis (OR: 1.30, CI: 1.03 to 1.64, p = 0.025) for individuals with poor weight perception.ConclusionThis study highlights the positive association between appropriate weight perception and better outcomes in individuals with NAFLD. Poor weight perception increased the risk of adverse events and decreased inclination toward seeking weight loss treatment. Greater emphasis should be placed on dealing with weight perception in individuals with NAFLD for better treatment outcomes.
Post-operative neutrophil-to-lymphocyte ratio and outcome after thrombectomy in acute ischemic stroke
Authors: Li Shen-Jie , Cao Shan-Shan , Huang Pei-Sheng , Nie Xin , Fu Yang , Liu Jian-Ren 
Published: September 2022

BackgroundNeutrophil to lymphocyte ratio (NLR) is a novel inflammatory marker to predict adverse cardiovascular events. However, there is a lack of data on hemorrhagic transformation (HT) and neurological outcome after mechanical thrombectomy in acute ischemic stroke (AIS). We investigated whether NLR before and after thrombectomy for patients with AIS was associated with HT and neurological outcomes.MethodsWe performed a retrospective analysis of consecutive patients with anterior circulation AIS who underwent thrombectomy. HT was evaluated by CT within 24 h after thrombectomy. Clinical data had been collected retrospectively; laboratory data were extracted from our electronic hospital information system. NLR was obtained at admission (NLR1) and immediately after thrombectomy (NLR2). The main outcomes were post-interventional intracranial hemorrhage and unfavorable functional status (modified Rankin scale scores of 3–6) 3 months post-stroke.ResultsA total of 258 patients with AIS, according to the NIHSS (median 14), were included. NLR2 was higher in patients who developed HT after thrombectomy and unfavorable neurological outcomes 3 months post-stroke (p &lt; 0.001) than in those without HT or favorable outcomes, even after correction for co-factors [Odds Ratio (OR) 1.35 for HT, 95% confidence interval (CI)1.16–1.57, p &lt; 0.001, and 1.85 for unfavorable outcome, 95%CI 1.57–2.17, p &lt; 0.001]. The optimal cutoff value for the NLR2 as an indicator for auxiliary diagnosis of HT and the unfavorable outcome was 8.4 and 8.8, respectively.ConclusionNLR immediately after thrombectomy is a readily available biomarker of HT and neurological outcomes in patients with AIS.