bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical course, laboratory and instrumental markers of vascular inflammation in the Kyrgyz cohort of patients with Takayasu's arteritis
Authors: Koilubaeva G. M. , Bolotbekova A. M. , Egorova O. N. , Turatbekova A. T. , Tarasova G. M. , Suyunbai kyzy G. , Chukubaev M. A. , Turdukulov Z. E. , Usupbaeva D. A. 
Published: October 2022

Lack of highly sensitive and specific methods of laboratory and instrumental diagnostics leads to difficulties in timely verification of Takayasu's arteritis (AT).Objective: to analyze the clinical course, laboratory and instrumental markers of vascular inflammation in the Kyrgyz cohort of patients with AT.Patients and methods. The study included 75 patients with a reliable diagnosis of AT, who were hospitalized and observed on an outpatient basis at the clinic of the National Center for Cardiology and Therapy named after acad. Mirsaida Mirrakhimova from January 2011 to April 2022. Patients were examined using clinical, laboratory and instrumental methods once every 2 years. The follow-up period was 1–5 years in 45 (60%) patients and 6–15 years in the remaining 30 (40%) patients. All patients underwent a clinical and standard laboratory work-up with CRP and interleukin 6 levels assessment, as well as ultrasound Dopplerography of peripheral arteries in the color Doppler mapping mode and multislice computed tomography-panaortography.Results and discussion. Lesions of the common carotid (85.33%) and subclavian (84%) arteries were detected more often. Involvement of the abdominal aorta was noted in 60% of patients and was accompanied by stenosis of the renal arteries in 100% of cases. The clinical picture of the disease was mainly represented by cardiac pathology in the form of arterial hypertension (84%) and aortic regurgitation (68%) with the development of decompensated chronic heart failure in 15% of patients. During the dynamic observation, significant improvement in the course of the disease, clinical symptoms, decrease in the severity of vascular changes were not revealed, with the exception of a decrease in the clinical activity of AT (p<0.05) in one third of patients (37.4%). Conclusion. The severity of clinical manifestations and the course of AT in the Kyrgyz cohort was due to cardiovascular pathology. As dynamic observation showed, the lack of significant improvement in the course of the disease was largely due to the long duration of chronic inflammation, late diagnosis, development of irreversible stenotic, occlusive and aneurysmal changes, as well as the fact that patients did not receive adequate pathogenetic therapy at the onset of the disease. Keywords: <0.05) in one third of patients (37.4%).Conclusion. The severity of clinical manifestations and the course of AT in the Kyrgyz cohort was due to cardiovascular pathology. As dynamic observation showed, the lack of significant improvement in the course of the disease was largely due to the long duration of chronic inflammation, late diagnosis, development of irreversible stenotic, occlusive and aneurysmal changes, as well as the fact that patients did not receive adequate pathogenetic therapy at the onset of the disease.
Back pain and assessment of ankylosing spondylitis activity during gestation: symptoms reflecting exacerbation of the disease and pregnancy
Authors: Krichevskaya O. A. , Dubinina T. V. , Ilinykh E. V. , Gluhova S. I. , Demina A. B. , Andrianova I. A. , Kulikov I. A. , Skripkina I. Iu. 
Published: October 2022

Objective: to study the dynamics of back pain severity and the frequency of its individual components, characterizing the inflammatory and mechanical rhythm, on the background of gestation in women with ankylosing spondylitis (AS) and compare them with manifestations of dorsopathy in healthy pregnant women; to determine the information value of BASDAI during pregnancy, i.e. to identify its components with the optimal sensitivity and specificity ratio for assessing AS activity during gestation.Patients and methods. The main group consisted of 49 pregnant women with AS who met the modified New York criteria of 1984. The average age of patients was 31.7±4.9 years, the average duration of the disease was 134.4±85.8 months. BASDAI for trimesters of pregnancy was: 2.3 [1.2; 4.4], 2.8 [1.4; 4.2] and 2.2 [1.6; 4.0]. The control group included 51 pregnant women with back pain associated with gestation, without rheumatic diseases. The average age was 28.0±4.4 years. The intensity of back pain was assessed on a numerical rating scale. ROC-analysis was performed with calculation of the area under the curve (AUC) of each component of BASDAI in each pregnancy trimester.Results and discussion. More than 80% of pregnant women with AS experienced back pain, while the intensity of general back pain did not differ from that in the control group. Night back pain with improvement on awakening in the main group was present in 70%, 58% and 68.8% of women, respectively, in the I-III trimesters; its intensity was 3 [1; 5], 3.5 [3; 6] and 3.4 [2; 5] respectively; the frequency and severity of night pain were higher than in the control group. The number of women with improvement after exercise in the II and III trimesters did not differ in both groups. In the second half of pregnancy, 40% of AS patients noted improvement during rest, 52.1% – increased pain after exercise; the frequency of mechanical rhythm pain elements remained lower than in the control group. The AUC value for BASDAI in the first trimester was 0.74; AUC of all BASDAI components was >0.5. In the II and III trimesters, the AUC values for fatigue and back pain were 0.8.Conclusion. During pregnancy the vast majority of women with AS experience back pain, the nature of which changes in the second half of gestation. Night pain that improves on awakening reflects AS activity and is not related to pregnancy. The BASDAI components of severity and duration of morning stiffness have the highest classification value during pregnancy.
UJI BEDA KUALITAS PELAYANAN E-KTP DI KOTA SURAKARTA DAN KOTA SEMARANG
Authors: Sulandari Susi 
Published: October 2022

Public services as the focus of the discipline of Public Administration remains interesting to observe because of the services provided by government officials to the public is still considered unsatisfactory. One of the problems of service in Indonesia is about administrative services, services e – KTP (identity cards). Surakarta and Semarang, both have been doing identity card service. Based on thr results of the initial survey in two cities, there are still many obstacles faced in the creation of identity card service.In this study, researchers will try to describe the service quality of e – KTP in Surakarta and Semarang, and will see no different whether or not the service quality of e – KTP in both cities. Type research used in this study is a quantitative study. The population of all citizens Surakarta and Semarang aged over 17 years and over. Becauseof the breadth of both cities used the sampling area, the city of Surakarta elected Laweyan districts and sub- districts of Semarang Pedurungan elected. Then each district taken 100 respondentsby means accidental. Analysis using interpretation of data : use of frequency distribution table predetermined number of respondents in the sample, the average sought to determine the caregories of service quality based on the resulth of the research, supplemented by interviews with respondent and the data to test the hypothesis used different test calculation of services quality in the city of Surakarta and Semarang.The result of this study concluded that the quality of service both in the district e KTPPedurungan Semarang and Surakarta in district Laweyan results showed good all categories, but it’s god when seen in different positions of the class interval, for the districtLaweyan Surakarta both categories at the upper limit of the interval 3,11 where as in the district Pedurungan Semarang, good bit closer to the lower limit of interval is 2,89. Based on the calculation results obtained by different test t value is equal to 3,004 with a sig 0.04. because the siq < 0,05 then it can be concluded that Ho is rejected, meaning that the average quality of service in the district Laweyan e KTP Surakarta identuty card service quality in the district of Semarang Pedurungan is not same (different). When viewed from its average of the quality of services in the district Laweyan Surakarta better than the service quality of e KTP in district Pedurungan Semarang. However, the different is very thin.
DECENTRALIZATION OF HOUSING POLICY FOR LOW-INCOME COMMUNITIES IN URBAN AREAS: AN ANALYSIS OF POLITICAL, FISCAL AND, ADMINISTRATIVE POLICY
Authors: Sururi Ahmad 
Published: October 2022

The purpose of this study is to discuss housing decentralization policies for urban Low-Income Communities based on three decentralization issues, namely politics, fiscal, and administration, and to recommend the concept of housing decentralization as an instrument and housing policy reform. The idea of decentralization of housing policy can’t be separated from various problems such as the debate over the authority of housing policy, the dependence of the regional government's housing budget on the central government, and various other obstacles. This study employed academic literature review related to decentralization studies and housing policies. The results of the study show that the three decentralization issues that are correlated with urban housing policies for Low-Income Communities have not yet fully provided an optimal impact on the realization of the ideal and desirable urban housing policies for Low-Income Communities. However, the very strong relationship between the three issues of decentralization and urban housing policy can be an important idea and recommendation to promote housing decentralization as an instrument and direction of urban housing policy reform for Low-Income Communities in Indonesia in the future.
Viability of seeds of two varieties of Coffea arabica L. using different pretreatments in the tetrazolium test
Authors: BUENDÍA CONTRERAS José Duván , MORENO ROZO Laura Yolima , SALAZAR MERCADO Seir Antonio 
Published: October 2022

This research attempted to determine the efficacy of the tetrazolium test in the evaluation of the seed viability of two varieties of Coffea arabica L. (‘Castillo’ and ‘Cenicafé’). The fruits were obtained from crops located in the municipalities of Salazar de las Palmas and Arboledas (Norte de Santander - Colombia). The test was carried out with embryos manually extracted from the seeds using tweezers. Three pretreatments were established: distilled water, sodium hypochlorite (2.5 %), sucrose (10 %), and a control (no pretreatment). Embryos were placed in a cysteine solution (0.5 %) to prevent oxidation, then immersed in tetrazolium solutions with concentrations of 0.035 %, 0.075 %, and 0.1 % for a period of 6, 9, and 12 hours in darkness. The results of the viability test were validated with seed germination, using the wet paper towel method in darkness. The best viability percentages were found with the application of sodium hypochlorite (NaClO 2.5 %), with a high correlation with the germination percentage. The use of pretreatments improved the efficiency of the viability test and allowed the use of low concentrations of the reagent (0.035 %), giving the farmer a quick and less expensive alternative to determine germination capacity.
Existence and Hyers–Ulam stability of solutions to a nonlinear implicit coupled system of fractional order
Authors: Zada Akbar , Ali Asfandyar , Riaz Usman 
Published: October 2022

AbstractIn this typescript, we study system of nonlinear implicit coupled differential equations of arbitrary (non–integer) order having nonlocal boundary conditions on closed interval [0, 1] with Caputo fractional derivative. We establish sufficient conditions for the existence, at least one and a unique solution of the proposed coupled system with the help of Krasnoselskii’s fixed point theorem and Banach contraction principle. Moreover, we scrutinize the Hyers–Ulam stability for the considered problem. We present examples to illustrate our main results.
Figurative language and persuasion in CPG sermons: The Example of a Gĩkũyũ televangelist
Authors: Njuguna Bernard G. , Schröder Helga 
Published: October 2022

Abstract
As a part of religious discourse, Christian sermons are a “…persuasive discourse par excellence” (Adams 2019:7). This is more pronounced in the Christian Prosperity Gospel (CPG), a system of thought and belief in which preachers
The word preacher and speaker are used interchangeably in this paper.
attempt to convince audiences to donate to their churches with the expectation that God will reward them with health and wealth. Previous research shows that the use of metaphors and metonymies pervade CPG sermons but an explanation on the mechanisms through which they persuade is rarer. With this in mind and viewing CPG sermons from their persuasive angle; this paper sets out to investigate how metaphors and metonymies are used for persuasion purposes in televised sermons presented in the Gĩkũyũ language
Gĩkũyũ is the language of the Agĩkũyũ who are largely found in central Kenya as well as in some other parts of the country. It is a Bantu language classified as a Zone E (E51) language by Guthrie (1971). According to the 2019, Population and Housing Census, the gĩkũyũ is the largest tribe in Kenya at 8,148,668 individuals. The community has dominated in televangelism but the position is changing due to the proliferation of many vernacular television stations.
. The data is drawn from authentic televised sermons. The findings indicate that metaphors and metonymies engender persuasion in sermons by affecting the perceived altruism and trustworthiness of a speaker in a sermon. This is done by means of manipulating various forms of distance suggested in the Media Proximization Approach (Kopytowska 2015, 2022). Metaphor is found to affect the axiological, epistemic, temporal and emotional distances while metonymy affects the axiological and spatial distances to activate certain pragmatic presuppositions which make them persuasive in a covert way.
Stein-Weiss inequality for local mixed radial-angular Morrey spaces
Authors: Wei Mingquan , Su Fangming , Sun Lanyin 
Published: October 2022

Abstract
In this article, a generalization of the well-known Stein-Weiss inequality for the fractional integral operator on functions with different integrability properties in the radial and the angular direction in local Morrey spaces is established. We find that some conditions can be relaxed for the Stein-Weiss inequality for local mixed radial-angular Morrey spaces.
Serpin family A member 1 is an oncogene in glioma and its translation is enhanced by NAD(P)H quinone dehydrogenase 1 through RNA-binding activity
Authors: Liu Wenjun , Du Min , Wan Hongping , Yang Hao , Deng Xiaorong , Chen Yu , Zhang Qian 
Published: October 2022

AbstractSerpin family A member 1 (SERPINA1) is expressed abundantly in gliomas and can predict unfavorable prognosis of patients with glioma. Studies have shown that nicotinamide adenine dinucleotide phosphate quinone dehydrogenase 1 (NQO1) can promote the proliferation of glioblastoma multiforme cells and enhance the expression ofSERPINA1, but its effects on glioma cells remain unknown. In this study, we explored the functions ofSERPINA1in glioma tumorigenesisin vitroand then investigated whetherNQO1affects the protein expression ofSERPINA1and its mRNA level. The results showed that the translation ofSERPINA1was suppressed while its mRNA level had no significant changes under the condition ofNQO1silencing. Luciferase reporter assay and biotin pull-down assay further indicated thatNQO1bond withSERPINA13′ untranslated region. miR-1321 was also identified to targetSERPINA1, repressing its mRNA and protein levels. SERPINA1andNQO1promoted glioma cell proliferation and suppressed cell apoptosis. Moreover,SERPINA1rescued the effects of sh-NQO1 in glioma cell malignant phenotypes. In conclusion, our findings showed that oncogeneNQO1and antioncogene miR-1321 bind to oncogeneSERPINA1to affect proliferation and apoptosis of glioma cells, which can bring new solution of antitumor treatments for glioma in the future.
Turning a polystyrene microsphere into a multimode light source by laser irradiation
Authors: Liu Shimei , Tie Shaolong , Chen Jingdong , Li Guangcan , Yang Jiaxin , Lan Sheng 
Published: October 2022

Abstract
Polystyrene (PS) is generally considered as a passive optical material that is transparent to light with wavelengths longer than 300 nm. In practice, PS micro- and nanospheres with uniform sizes are usually used to build photonic crystals based on self-assembly mechanism. Here, we demonstrate experimentally that PS microspheres supporting whispery gallery modes can be transformed into multimode light sources by laser irradiation. We show that a PS microsphere placed on a silica substrate can be lighted up when it is consecutively irradiated by using a 488-nm continuous wave laser beam with a pumping power above a threshold. Broadband luminescence emitted from the PS microsphere increases rapidly to a maximum value and decreases gradually with increasing irradiation time, implying the generation and degradation of a certain luminescent material upon laser irradiation. However, the PS microsphere is found to be damaged by high temperature based on morphology examination. By replacing the silica substrate with a thin silver film, the threshold laser power for lighting up a PS microsphere is dramatically reduced. More importantly, we can see enhanced luminescence intensities from the whispery gallery modes supported by the PS microsphere, which becomes an efficient multimode light source. Interestingly, the threshold laser power can be further lowered by inserting a molybdenum disulfide monolayer in between the PS microsphere and the silver film. As a result, the PS microsphere remains nearly unchanged except the formation of the luminescence material. Our findings open a new horizon for the interaction of polymer with laser light by exploiting the optical resonances supported by micro- and nanoparticles and pave the way for constructing photonic devices based on laser-induced luminescent materials in polymers.
Effect of freeze–thaw cycles on deformation properties of deep foundation pit supported by pile-anchor in Harbin
Authors: Cui Gaohang , Ma Shuxian , Liu Zhiqiang , Liu Shouhua , Xi Chen , Cheng Zhuo 
Published: October 2022

Abstract
In the course of the construction of deep foundation pits during the winter in seasonally frozen areas, the pit wall soil is often unstable due to frost heave and thawing settlement, which leads to hidden safety hazards in engineering construction. Based on the analysis of the deformation data of a pile-anchor supporting a deep foundation pit in Harbin obtained from monitoring during the winter, the influence of freezing and thawing cycles was investigated. The results show that the horizontal displacement in the middle of the shallow layer of the foundation pit is significantly larger than that on both sides during the freeze–thaw cycles, and the spatial effect becomes noticeable. The stress concentration at the external corner of the foundation pit, coupled with the effects of atmospheric precipitation and freeze–thaw cycles, led to the maximum growth rate of horizontal displacement up to 1.40 mm·day−1. The external corner effect is evident from 1 m in the shallow layer of the pit to the depth H/2 of the foundation pit. The support scheme is generally feasible, and we can appropriately enhance the support of the shallow layer of the foundation pit during the freeze–thaw cycles. For similar projects experiencing freeze–thaw cycles, the safety reserve can be appropriately enhanced when carrying out support design.
Distribution Features and Potential Effects of Serotonin in the Cerebrum of SOD1 G93A Transgenic Mice
Authors: He Pei , He Binjun , Li Shu , Chai Wen , Rao Wei , Zhu Yu , Chen Wenzhi , Zhang Ping , Zhang Xiong , Pan Haili , Xu Renshi 
Published: October 2022

AbstractSerotonin (5-HT) participates in the pathogenesis of amyotrophic lateral sclerosis (ALS), but its effects have not been completely clarified. Therefore, we observed the distribution features and potential effects of 5-HT in the cerebrum of G93A SOD1 transgenic (TG) and wild-type (WT) mice by fluorescence immunohistochemistry, Western blotting, ELISA, as well as motor function measurements. Both 5-HT and tryptophan hydroxylase-2 (TPH2) were mainly present in the limbic systems of the cerebrum, such as the glomerular layer of the olfactory bulb, nucleus accumbens, cingulate, fimbria of the hippocampus, mediodorsal thalamic nucleus, habenular nucleus, ventromedial hypothalamus nucleus, lateral hypothalamus area, dorsal raphe nucleus, and piriform cortex. TPH2 and 5-HT were expressed in cell bodies in the dorsal raphe nucleus and piriform cortex, while in other regions they were distributed as filaments and clump shapes in axons. The TPH2 distribution in the cerebrum of TG was significantly lower than that in WT in preset, onset, and progression stages. TPH2 expression in the fimbria of the hippocampus, mediodorsal thalamic nucleus, habenular nucleus, ventromedial hypothalamus nucleus and lateral hypothalamus area was increased in the onset stage and decreased in the progression stage, gradually decreased in the cingulate with disease progression and significantly decreased in the glomerular layer of the olfactory bulb and nucleus accumbens in the onset stage in TG. The number of mammalian achaete-scute homolog-1 in the subventricular zone (SVZ) in TG was significantly lower than that in WT, which was correlated with the TPH2 distribution. Double immunofluorescence staining showed that TPH2, mammalian achaete-scute homolog-1 and 5-HT were mainly expressed in neurons but rarely expressed in microglia or astrocytes in the piriform cortex. The relative fluorescence density of TPH2 in the cingulate region was negatively correlated with the disease severity. Our findings suggest that 5-HT plays a protective role in ALS, likely by regulating neural stem cells in the subventricular zone that might be involved in neuron development in the piriform cortex.