bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hybrid magnetic materials based on polyethylene containing Co and Ni nanoparticles
Authors: Vasil’kov Alexander Yu. , Budnikov Alexander V. , Naumkin Alexander V. 
Published: July 2022

New hybrid magnetic materials based on HDPE filled with Со and Ni nanoparticles have been prepared via the metal vapor synthesis. Properties of the metal-polymer composites have been elucidated as a function of MVS parameters and metal nature. The Faraday method has been applied to characterize the magnetic properties of the systems. The microstructure of the samples has been studied with a number of X-ray and synchrotron techniques, including XRD, EXAFS and SAXS. Core-level and valence band spectra were measured by XPS. The peak at binding energy of 282.8 eV characteristic of C-Ni bond was recorded in the C 1s spectrum. It was shown that properties of nanocomposite materials with similar compositions are determined both by the synthesis conditions and post-synthesis factors.
Nano-composites and their applications: A review
Authors: Din Sajad Hussain , Shah M. A. , Sheikh N. A. , Butt M. Mursaleen 
Published: July 2022

Nanocomposites are high performance materials which reveal rare properties. Nanocomposites have an estimated annual growth rate of 25% and fastest demand to be in engineering plastics and elastomers. Their prospective is so prominent that they are valuable in numerous areas ranging from packaging to biomedical applications. In this review, the various types of matrix nanocomposites are discussed highlighting the need for these materials, their processing approaches and some recent results on structure, properties and potential applications. Perspectives include need for such future materials and other interesting applications. Being environmentally friendly, applications of nanocomposites propose new technology and business opportunities for several sectors of the aerospace, automotive, electronics and biotechnology industries.
Apuntes sobre fotografía y memoria a partir de la relectura de Ante el dolor de los demás de Susan Sontag
Authors: Pérez Daza Johanna , Prada Wilson 
Published: July 2022

Conocer el efecto de la fotografía en la memoria ha sido un tema de interés recurrente. Desde su invención, la fotografía se ha asociado a la memoria y el anhelo de atrapar el tiempo, elevadas aspiraciones que se han ido transformando a partir de sus usos y masificación. En su libro Ante el dolor de los demás (2003), Susan Sontag examina la fotografía en el contexto de la guerra, el dolor y la compasión, sus nexos con el pasado y su capacidad para sacudir las conciencias y la opinión pública. En el presente artículo revisaremos la vigencia de algunos de sus planteamientos, atendiendo las intersecciones de la fotografía con tres conceptos clave: memoria, poder y violencia. Las posibilidades de circulación de la fotografía, los modos de recepción y producción, así como los intereses por posicionar unas imágenes y desechar otras, por recordar unas y olvidar otras, abren discusiones éticas y preguntas que, adquieren relevancia, en el complejo escenario actual.
The experimental study of the immunomodulating action of Semax and Selank on the model of „social” stress
Authors: Yasenyavskaya A.L. , Samotrueva M.A. , Myasoedov N.F. , Andreeva L.A. 
Published: July 2022

Abstract
This study is devoted to the experimental study of the immunocorrecting action of Semax (Met-Glu-His-Phe-Pro-Gly-Pro) and Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro) on the model of “social” stress formed as a result of sensory contact and inter-confrontation. Functional activity of the immune system of laboratory animals was assessed on the basis of standard immunopharmacological tests: delayed-type hypersensitivity reaction (DTH), direct agglutination test (DAT), latex test for studying the phagocytic activity of peripheral blood neutrophils, and evaluation of changes in the leukocyte formula. As a result of the experiment, it was found that, under the influence of “social” stress, changes in the immune response are multidirectional, which confirms the theory of “immune disbalance” under the action of stressors. As a result of studying the influence of Semax and Selank on the model of “social” stress, it was found that the drug proved to be an effective corrector, restoring the cellular and humoral immunogenesis reactions, the phagocytic activity of neutrophils, which indicates the presence of immunomodulating properties, and emphasizes the need for further studies in this scientific direction. This study expands the scientific research base in the field of immunoreaction under stress-induced conditions with the aim of further developing a pharmacological strategy for correcting the revealed disorders by means of substances of a neuropeptide structure.
Evaluation of antitumoral effect of mistletoe fruit extract on Ehrlich ascites tumor cells with muse cell analyzer and argyrophilic nucleolar organizer region staining method
Authors: Ateş Şükrü , Ülger Harun , Yilmaz Seher , Karatoprak Gökçe Şeker , Al Özge , Uçar Sümeyye , Taştan Mustafa , Tokpinar Adem , Alpa Şerife , Farooqi Ammad Ahmad 
Published: July 2022

Abstract

Introduction
Mistletoe has been used alone or as a complementary therapy in the treatment of different diseases for years. In this study, the antitumoral effect of mistletoe fruit extract on Ehrlich ascites tumor (EAT) cells was evaluated.

Materials and Methods
EAT cells from preformed stock mice were transferred to culture dishes containing 5-fluorouracil (5-FU) and mistletoe extracts at different doses (100, 200, 400, and 800 μg/ml). These cells were incubated at 37 °C in an environment with 95% humidity and 5% CO2. At the end of the incubations, the apoptosis status of the cells, cell cycle, mitochondrial membrane potential, and proliferation status with the argyrophilic (Ag) nucleolar organizer region staining (NORs) method were evaluated.

Results
As a result, it was observed that the mistletoe fruit extract and 5-FU induce apoptosis of EAT cells. It was concluded that the 5-FU substance arrests the cell cycle at the G0/G1 stage, while the mistletoe arrests the cell cycle at the S and G2/M stages. The depolarization rate of the mistletoe treated cells was higher. As a result of the evaluation made with the AgNORs method, it was seen that mistletoe and 5-FU could be effective in reducing the proliferation of EAT cells.

Conclusions
It was seen that mistletoe fruit extract could be effective in stimulating the apoptosis and depolarization of cancer cells. The results of other studies in the literature and our study support each other. It was concluded that the mistletoe plant may be useful in cancer treatment.
Atopic dermatitis: Current standards of diagnosis and treatment, including the latest methods of management
Authors: Fornal Rafał , Książkiewicz Anna , Fornal Aleksandra , Zarzycka Danuta 
Published: July 2022

Abstract
Atopic dermatitis (AD) is a chronic relapsing disease which causes characteristic eczematous skin lesions. The most common symptoms of atopic dermatitis are persistent pruritus, xerosis, and skin lesions with a typical location and appearance that changes with the patient’s age. The prevalence of the disease in the pediatric population is estimated at 10% to 30%, while in adults it ranges from 1% to 3%. The number of people who suffer from AD is rising every year. The pathophysiology of the disease is complex and multifactorial. It involves elements of epidermal barrier dysfunction, alterations in cellular immune response, IgE hypersensitivity, and environmental factors. AD significantly reduces the quality of life of both patients and their families. Patients with AD are at higher risk for neuropsychiatric disorders such as depression, attention-deficit/hyperactivity disorder, and headaches. The decreased quality of life of AD patients and their families is associated with the discomfort of recurrent and chronic inflammatory skin lesions, persistent pruritus, and the inconvenience of long-term therapy. It also affects the psychological development of children, contributes to behavioral disorders (hyperactivity, hypersensitivity) and impacts many areas of family life such as sleep, leisure activities, and relationships between family members. The basic treatment of AD is avoidance of potential harmful factors, proper care in the treatment of exacerbations, topical corticosteroids, and calcineurin inhibitors in proactive therapy. In some patients who meet age criteria, phototherapy and cyclosporine should be considered. In individuals with severe AD who do not respond to topical treatment and who will not benefit from general therapy, dupilumab, a biologic drug, is the treatment of choice. Biologic treatment has an increasingly important place in the effective and modern therapy of AD. Currently, new biologic drugs are being researched, which may bring a therapeutic revolution in AD in the future. Allergen immunotherapy in patients with AD should be carefully evaluated on an individual basis, as proper selection of patients with documented IgE-dependent sensitization is important for the success of this therapy. Close collaboration with the patient and their caregivers, education, and psychological support as appropriate are integral to the treatment.
Metanephrine and Normetanephrine Urine Excretion in Patients with PCOS
Authors: Robeva R. , Arnaudova N. , Kirilov G. , Elenkova A. , Zacharieva S. 
Published: July 2022

Abstract

Aims: The present study aims to investigate the association between catecholamine metabolites (normetanephrine [NMN] and metanephrine [MN]) and polycystic ovarian syndrome (PCOS) and its clinical manifestations.

Materials and methods: A total of 60 female patients (18-37 years) were included in the study. Twenty-five healthy women and 35 patients with PCOS provided blood and urine samples. Anthropometric, biochemical, and hormonal parameters, e.g. immunoreactive insulin, total testosterone, gonadotropins, and dehydroepiandrosterone-sulfate (DHEAS) have been investigated. Twenty-four-hour urinary metanephrines (MN and NMN) were measured by radioimmunoassay technique.

Results: MN and NMN showed a strong positive correlation (r = +0.645, p < 0.001) in women with PCOS, but nephrines were not significantly associated with the hormonal, anthropometric, and metabolic parameters of the patients (p > 0.05 for all). No differences in urinary nephrines concentrations between women with PCOS and healthy individuals after adjustment for age and BMI were established. However, lower 24-hour urinary MN levels predicted the development of menstrual irregularity after adjustment for age and BMI (OR = 1,015 [95% CI 1,001-1,029], p = 0,036).

Conclusions: Adrenomedullary dysfunction might influence the development of chronic anovulation in young women.
Cost-Utility Analysis of Open Hernia Operations in Bulgaria
Authors: Kirilova-Doneva M. , Kamusheva M. , Gerasimov N. , Petrova G. 
Published: July 2022

Abstract

Background: Hernia surgery procedures are among the most frequently performed in Bulgaria. An open, mesh-based repair is a standard method for hernia repair. From a societal perspective, a cost-utility analysis of open hernia surgical procedures performed in Bulgaria is necessary in light of the economic and social burden that poses this health issue. The aim of the study was to perform an economic evaluation of the quality of health results after a conventional elective hernia operation with implanted light and standard meshes.

Methods: The cost of elective hernia operation with standard and light meshes was calculated as a sum of direct and indirect costs. Incremental cost-effectiveness ratio (ICER) for conventional hernia operation was calculated as health improvement was measured in quality-adjusted life years (QALY) reported in a previous study. Deterministic sensitivity analysis was applied to evaluate the changes in the ICER values in case of planned inguinal hernia operation.

Results: The cost of operation with standard meshes is less than operation with light meshes. The difference is in the range 55-200 EUR. The additional costs per one QALY gained for light meshes are far below the recommended threshold values which identified these meshes as cost-effective.

Conclusions: The study presents evidence for cost-effectiveness of light meshes.
Survival rate and prognostic factors of oral squamous cell carcinoma in Indonesia: A single-center retrospective study
Authors: Kartini Diani , Kurnia Ahmad , Putri Shabrina Rizky , Thaher Tiffany Christina , Handjari Diah Rini , Khoe Levina Chandra , Marcevianto Kevin Varian 
Published: July 2022

Abstract

Background
Oral squamous cell carcinoma (OSCC) is the sixth most common malignancy in Asia. Most patients in Cipto Mangunkusumo Hospital have been diagnosed with an advanced stage. There had not been any survival study for OSCC in Indonesia. This study aimed to investigate the survival rate and prognostic factors of OSCC in Cipto Mangunkusumo Hospital.

Methods
A retrospective cohort study was conducted on OSCC patients diagnosed and treated in Cipto Mangunkusumo Hospital from 2014 to 2018. Data regarding age, gender, site of the primary lesion, clinical stage of the disease, tumor differentiation, invasion, and surgical margins were collected. The main outcomes measured were overall survival (OS) and disease-specific survival (DSS). The predictors of survival were then determined.

Result
169 patients were included. The majority of patients were male (51.5%) and above 50 years old (55.6%). The most prevalent tumor site was the tongue (72.8%) followed by buccal mucosa (13%). The majority (82.2%) of patients had advanced (clinical stage IV) disease at diagnosis. A smaller majority of patients had a well-differentiated tumor (60.4%) and a low-grade tumor (53.8%). The worst one-year and two-year overall survival rates were found in the stage IV group (53.5% and 37.5%, respectively). The disease-specific survival rate was 66.9%.

Conclusion
The one-year and two-year overall survival rates of OSCC in Cipto Mangunkusumo Hospital were 58.6% and 43.1%. Moreover, clinical stage, tumor size, and lymph node involvement were the most significant prognostic factors for OSCC.
Finite Element Method for Designing Large Section Underground Works by Sequential Excavation Method. Study Case: Lugoj-Deva Road Tunnel
Authors: Toderaș Mihaela 
Published: July 2022

Abstract
Any underground work requires the knowledge and application of appropriate techniques and technologies in all stages of implementation of such a project. An important problem in the design of underground works is the knowledge of the characteristics and behaviour of the massif in which the work will be carried out. It depends on the choice of the excavation solution appropriate to the existing real conditions, which will influence the duration of the work and the costs associated with it. The objective of this paper was to analyse and compare the total deformations of the contour of the underground work, assuming that the work is performed by sequential excavation method (S.E.M.): excavation in the horizontal direction and in the vertical direction. The finite element numerical simulation method was used for the convergence analysis, which showed that the total displacements of the tunnel gallery wall are smaller for the horizontal sequential excavation (SEM) variant, both for the hypothesis of coefficient of pressure in state of rest having the value K0 = 0.6, as well as for the hypothesis in which K0 = 2.27.
Determinations and Interpretations of the Contents of Heavy Metals from Food and Water Test Samples from Locations Near the Mining Perimeters of Baia Mare and Băiuț Area
Authors: Bud Adina 
Published: July 2022

Abstract
The paper presents the level of heavy metal contamination in the areas located in the vicinity of the mining perimeters in Baia Mare and Băiuț and the risk of their expansion in the future. Heavy metal contamination was analysed on water samples from wells, plants and milk from animals that consumed water from polluted streams.
Research Regarding Iron Sludge Recovery Technology
Authors: Traistă Eugen , Traistă Camelia 
Published: July 2022

Abstract
One of the most important wastes in iron metallurgy is the blast furnace sludge. This sludge consists of fine particles of iron ore, coke and fine particles of flux. The furnace sludge is characterized by the chemical composition similar to that of the furnace load, the major difference being the concentration of zinc and lead. Due to the similarity with the blast furnace load, this material, after pelletization, can be recycled in the technological process. However, this recirculation is limited by the zinc content, which significantly disrupts the operation of the furnace. This paper presents tests to reduce the zinc content of the furnace sludge by hydrometallurgical and pyrometalurgical processes.
Analysis of Orientation Accuracies in Underground Polygonal Routes
Authors: Filip Ofelia-Larisa , Filip Anca Daniela 
Published: July 2022

Abstract
Topography has an important role in the realization of underground mining works, hydro-technical constructions, roads, etc. Appropriate topographic measurements and processing are required to trace these objectives in the necessary safety and efficiency conditions. An appropriate topographic basis must first be established for which scientific analyzes focusing mainly on topographical guidance elements are required. It is considered an independent polygonal route, easy to achieve and with superior quality effects.
Methodology for Quantifying the Risk of Occupational Accident and / or Disease Specific to Complex Technical Systems
Authors: Furdui Peagu Daniela , Radu Sorin Mihai 
Published: July 2022

Abstract
This paper presents a scientific research in the field of the risk assessment, in order to secure the activities carried out in the presence of specific hazards of industrial work systems. The methodology for quantifying the risk of occupational is an innovative tool which highlights the analytical solution for quantify the occupational risks with impact, both on the human component, as well as at the level of the other component elements specific to the work systems.
Local and Regional Politics at the EU level: who is actually represented in the Committee of the Regions?
Authors: Bącal Paweł 
Published: July 2022

Abstract
One of the main reasons for the establishment of the Committee of the Regions was to provide the subnational level with the representation within the institutional system of the European Union. As the body advising the EU institutions, the Committee can influence the decision-making process. Since it consists of members of the local and regional authorities, one may ask if it does offer the opportunity for the peculiar territorial self-government units to be represented at the EU level. And in the broader terms – what does the relation between the general and particular interests look like in that regard? The article tries to determine if the Committee of the Regions is a suitable place for the individual territorial self-government unit to promote its interests. The findings of the paper are based on the author’s own empirical research conducted among the Polish members of the Committee. The results entitle the author to state that the territorial self-government units are represented in the Committee of the Regions and they have some benefits from being represented within this body.
Investigation of the Liquefaction Potential of Coal Ash Due to Seismic Loading
Authors: Slávik Ivan 
Published: July 2022

Abstract
Coal ash is a geomaterial with a metastable structure. This type of geomaterial is significantly susceptible to liquefaction as a result of seismic loads. An investigation of ash that is susceptible to liquefaction due to a seismic load can use the CPT penetration test. This method of investigating liquefaction was developed based on numerous penetration tests of sandy or silty–sandy soils and was developed at the Workshop on the Evaluation of Soil Liquefaction Resistance, NCEER, Salk Lake City, Utah, USA, 1996. In the present article, the results of the CPT penetration test conducted at the Rosina ash tailings pond in Žilina in Slovakia, are analyzed using the NCEER methodology. The safety factor for ash liquefaction was expressed based on the penetration resistance values measured in the CPT tests using the ‘LiquefyPro’ software. The safety factor in the liquefaction of the ash sediment was expressed by changing the level of seeping water in the body of the tailings pond, the unit weight of coal ash, and the seismic acceleration.
Effect of Employee Benefits on Organizational Growth of Consumer Goods Firms in Nigeria
Authors: Agubata Nonye Stella , Okolo Livinus Ikenna , Ogwu Stephen Obinozie 
Published: July 2022

Abstract
Employees have physical and emotional needs so the wellbeing of the workforce cannot be overlooked. This study examined the effect of employee benefits on business growth using a sample of ten consumer goods companies listed on the Nigerian Stock Exchange. The panel data used in this study is from the annual report of the individual companies from 2012-2019 and was analyzed using the Eviews. The study carried out descriptive statistics with undistorted original data; tests such as Pearson correlation and the variance inflation factor were also performed. Finally, the Pesaran CD test was used to check the cross-sectional dependence before estimating the panel regression, which corrected the cross-sectional dependence with Period SUR. The Fixed Effect regression result showed that gratuity, pension and medical allowance, which were the measures of employee benefits, had a positive significant effect on organizational growth (measured in terms of assets), The study, therefore, concludes that employee benefits in the consumer goods sector have a positive and significant effect on business growth, with the exception of the medical allowance. Therefore, the study recommends that business organizations trying to get the most out of employees for growth should initiate and improve the payment of benefits to employees and initiate and improve pension payment.
Understanding and Promoting the ‘Leaving No One Behind’ Ambition Regarding the Sustainable Development Agenda: A Review
Authors: Mensah Justice , Mensah Amos , Mensah Aba Nyameyie 
Published: July 2022

Abstract
With the adoption of the 2015–2030 Sustainable Development Goals (SDGs), the United Nations (UN) Member States pledged to ensure that no one would be left behind. This article highlights the essentials (meaning, importance, history, framework, pillars, related key studies, and role of key actors) in respect of the ‘Leaving No One Behind’ (LNOB) pledge. The review shows that the LNOB pledge has three-pronged strategic development imperatives: (i) to end poverty in all its forms, (ii) to stop the discrimination and inequality that have resulted in unequal outcomes for the disadvantaged population, and (iii) to reach the furthest behind first. The framework for achieving the ambition is anchored on implementing the SDGs, ‘empowering the left-behind by ensuring their meaningful participation in decision-making; and enforcing equity-focused policies, and interventions with a dedicated budget to support rights-holders and duty-bearers to address the deprivations of the people left behind. The UN, Governments, Businesses, Civil Society Organisations and other actors should collaborate to translate the mantra into reality by addressing the pervasive societal issues of poverty, inequality, and discrimination. Germane to achieving the LNOB ambition are reliable disaggregated people-centered data, research, and stakeholder/actor commitment to the pledge.