bluuebunny/crossref_metadata_2025_split huggingface dataset:
The social system of the lava lizard, Microlophus atacamensis: the interplay between social structure and social organization
Authors: Utsumi Kaera , Staley Catherine , Núñez Herman , Eifler Maria A. , Eifler Douglas A. 
Published: November 2022

AbstractBackgroundAnimal social systems can be described through four main components: social structure, social organization, mating system, and care system. Social structure describes the relationships between individuals in a population, while social organization describes the group composition, size, and spatiotemporal variation of a population. We use the frameworks of social structure and social organization to study the social system ofMicrolophus atacamensis, a lizard found in the rocky intertidal zone along the Chilean coast. The areaM. atacamensisinhabits poses specific challenges stemming from their use of two distinct habitat types in the intertidal zone: they forage in the cool areas near the water’s edge and use large rocks in more inland areas for basking and refuge.MethodsOur assessment of their social system focused on two separate populations: one to characterize social structure by means of focal observations and social network analysis, and a second to assess social organization via home range and core area analyses. Further, we examined the social system in two habitat types that comprise the intertidal zone: cobble fields and interspersed large rocks.ResultsSocial network analysis revealed an interconnected network with a few highly central individuals. Body size influenced the outcomes of aggressive interactions, with interactions being more common in cobble fields where males had more associates and more repeated interactions than females. Spatial analyses revealed that the social organization ofM. atacamensisis characterized by (1) high home range overlap, specifically in the cobble fields and (2) relatively exclusive core areas dispersed across both habitat types.ConclusionA social system is composed of both cooperative and competitive behaviors. While our study focused on competitive interactions, the extent and influence of cooperative behaviors is still unclear and merits future research. We suggest thatM. atacamensishas a variable social system in which territoriality on large rocks affects access to stationary resources in that habitat (e.g., basking sites and refuges), while competition in the cobble fields could lay the foundation for a system of dominance relationships controlling access to variable food resources in cobble field areas of the intertidal zone.
Darier disease, hypertrophic / vegetating type
Authors: Cardoso Caroline Passos , Almeida Herbert Ives Barretto , Neves Nilma Antas , Leal Fabiola , Athanazio Daniel Abensur 
Published: November 2022

Abstract
Background
A hypertrophic / vegetating variant of Darier disease causing massive verruciform genital tumors is exceedingly rare.

Case presentation
A woman in her late 50s underwent wide resection of vulva and inguinal skin due to massive verruciform lesion. She had crusted / keratotic plaques with appearance of follicular keratosis keratosis (with a greasy, warty texture) in the back, neck, face, and extremities for 27 years. Previous biopsies from lesions elsewhere 27 years ago and along the years showed the same verruciform, pseudoepitheliomatous pattern, with no atypia. The diagnosis in those biopsies as well in the resected specimen was Darier disease, hypertrophic / vegetating type. All sampled areas showed the same pattern of parakeratosis, dyskeratosis (corps ronds and grains), suprabasal acantholysis and pseudoepitheliomatous hyperplasia with prominent anastomosing cords of elongated rete ridges (with a syringofibroadenoma silhouette). HPV hybridization situ was negative.

Conclusion
Awareness of hypertrophic variant of Darier disease is of important to avoid the diagnosis of malignant transformation in long term disease – which is an exceedingly rare event.
Signal processing methods for crosswell electromagnetic imaging system
Authors: Zang Defu , Ji Yongli , Chao Yongsheng , Li Zhiqiang 
Published: November 2022

The principle of crosswell electromagnetic (EM) imaging is similar to that of induction logging. The difference between them is that conventional induction logging can only measure the formation conductivity within a few meters around the well. However, crosswell EM imaging can be used in two wells with a separation distance of up to 1000 m. Several novel signal processing methods for crosswell EM imaging systems are developed for calibration, casing correction, and hybrid Jacobian matrix calculation. To conveniently perform calibration on the ground, the EM field formula in a vertical layered media is derived based on Maxwell equations, and the relationships between the received signal and frequency, formation conductivity, and transceiver spacing are subsequently derived. Furthermore, a new calibration method is developed. The EM field formula for a radial layered media is derived, and the analytical expressions describing the relationship between the receiving signal and borehole parameters, metal casing parameters, formation parameters, and receiver location are obtained. The effects of mud resistivity, metal casing position, metal casing resistivity, permeability, cement ring resistivity, transmitting frequency, and receiver location on the crosswell EM receiving signal are simulated. It is determined that only the casing required a correction. The influence of the metal casing is corrected by establishing a database. The difference between the corrected data and data obtained without a metal casing is less than 1%. There is a large error in the calculation of the Jacobian matrix in some regions when Green’s function was used. A hybrid Jacobian matrix calculation method combining local perturbation and a global Green’s function is developed, which significantly reduced the error and improved the inversion accuracy.
Circulating Tumor DNA as a Marker of Minimal Residual Disease After Radical Resection of Colorectal Liver Metastases
Authors: Marmorino Federica , Prisciandaro Michele , Giordano Mirella , Ortolan Elisa , Crucitta Stefania , Manca Paolo , Antoniotti Carlotta , Valenti Marta Maria , Danesi Romano , Conca Veronica , Mazzoli Giacomo , Boccaccino Alessandra , Carullo Martina , Martinetti Antonia , Sottotetti Elisa , Masi Gianluca , Sposito Carlo , Zaffaroni Nadia , Milione Massimo , Fontanini Gabriella , Del Re Marzia , Pietrantonio Filippo , Cremolini Chiara 
Published: November 2022

PURPOSE Prognostic tools to estimate the risk of relapse for patients with liver-limited metastatic colorectal cancer (LL-mCRC) undergoing resection with curative intent are needed. Circulating tumor DNA (ctDNA) as a surrogate of postsurgical minimal residual disease is a promising marker in localized CRC. We explored the role of postoperative ctDNA as a marker of minimal residual disease in patients with radically resected LL-mCRC. MATERIALS AND METHODS Seventy-six patients with LL-mCRC were retrospectively included. DNA from tumor tissue was sequenced, and one somatic mutation was then assessed by digital droplet polymerase chain reaction in plasma samples collected after surgery to identify the persistence of ctDNA. Relapse-free survival and postresection overall survival were compared between patients with positive vs negative postoperative ctDNA. RESULTS ctDNA was found in 39 (51%) of 76 patients with LL-mCRC. At a median follow-up of 77 months, 33 of 39 ctDNA-positive patients and 20 of 37 ctDNA-negative patients experienced disease relapse ( P = .008). ctDNA-positive patients reported significantly shorter RFS than ctDNA-negative ones (median RFS 12.7 v 27.4 months hazard ratio, 2.09, P = .008). In the multivariable model including other prognostic covariates, this association was still significant ( P = .046) and a trend toward shorter overall survival among ctDNA-positive patients was reported (hazard ratio, 1.65, P = .183). CONCLUSION The detection of postsurgical ctDNA is an independent negative prognostic marker and identifies patients at high risk of relapse after liver metastases resection.
Influence of interaction-generated anisotropy on the antiferromagnetic spin system on the octahedral lattice
Authors: Jurčišinová E. , Jurčišin M. 
Published: November 2022

Abstract
The phase diagram of the antiferromagnetic spin-1/2 Ising-like model on the octahedral lattice with different strength of the nearest-neighbor interactions in all horizontal planes of the lattice in comparison to all nearest-neighbor interactions between them is investigated in the appropriate recursive lattice approximation. The existence of the intermediate phase that separates two dominant antiferromagnetic phases is shown and the nature of all phase transitions between various phases is determined. The sublattice as well as total magnetization properties of all phases of the model are studied. It is shown that the introduced interaction-generated anisotropy has strong impact on the very existence of the phenomenon of the weak ferromagnetism as well as on its magnetization properties in such pure antiferromagnetic spin systems.
Changing the Name of Diabetes Insipidus: A Position Statement of the Working Group for Renaming Diabetes Insipidus
Authors: Arima Hiroshi , Cheetham Timothy , Christ-Crain Mirjam , Cooper Deborah , Drummond Juliana , Gurnell Mark , Levy Miles , McCormack Ann , Newell-Price John , Verbalis Joseph G , Wass John ,   The Working Group for Renaming Diabetes Insipidus, Arima Hiroshi , Cheetham Timothy , Christ-Crain Mirjam , Gurnell Mark , Cooper Deborah , Drummond Juliana , Levy Miles , Gurnell Mark , McCormack Ann , Verbalis Joseph G , Newell-Price John , Wass John 
Published: November 2022

Abstract
Recent data show that patients with a diagnosis of diabetes insipidus (DI) are coming to harm. Here we give the rationale for a name change to arginine vasopressin deficiency and resistance for central and nephrogenic DI, respectively.
A tale of two fish tails: does a forked tail really perform better than a truncate tail when cruising?
Authors: Tack Nils B. , Gemmell Brad J. 
Published: November 2022

ABSTRACT
Many fishes use their tail as the main thrust producer during swimming. This fin's diversity in shape and size influences its physical interactions with water as well as its ecological functions. Two distinct tail morphologies are common in bony fishes: flat, truncate tails which are best suited for fast accelerations via drag forces, and forked tails that promote economical, fast cruising by generating lift-based thrust. This assumption is based primarily on studies of the lunate caudal fin of Scombrids (i.e. tuna, mackerel), which is comparatively stiff and exhibits an airfoil-type cross-section. However, this is not representative of the more commonly observed and taxonomically widespread flexible forked tail, yet similar assumptions about economical cruising are widely accepted. Here, we present the first comparative experimental study of forked versus truncate tail shape and compare the fluid mechanical properties and energetics of two common nearshore fish species. We examined the hypothesis that forked tails provide a hydrodynamic advantage over truncate tails at typical cruising speeds. Using experimentally derived pressure fields, we show that the forked tail produces thrust via acceleration reaction forces like the truncate tail during cruising but at increased energetic costs. This reduced efficiency corresponds to differences in the performance of the two tail geometries and body kinematics to maintain similar overall thrust outputs. Our results offer insights into the benefits and tradeoffs of two common fish tail morphologies and shed light on the functional morphology of fish swimming to guide the development of bio-inspired underwater technologies.
Do Intramuscular Temperature and Fascicle Angle Affect Ultrasound Echo Intensity Values?
Authors: PINTO MATHEUS DAROS , SILVEIRA PINTO RONEI , NOSAKA KAZUNORI , BLAZEVICH ANTHONY JOHN 
Published: November 2022

ABSTRACT

Purpose
Ultrasound-derived echo intensity (EI) has been used as a physiological marker for changes in skeletal muscle “quality” with physical training, disuse, aging, and neuromuscular disorders. However, the methodological and physiological factors influencing EI and its longitudinal change are still unclear. Here, we performed two separate experiments to investigate the effects of muscle temperature and fascicle angle, which are known to influence muscle tissue and sound wave properties and therefore affect EI.

Methods
In experiment 1 (n = 16, 28.0 ± 6.6 yr), vastus lateralis (VL) ultrasonographic images were acquired and intramuscular temperature continuously recorded for 15 min after 20 min of heating to 40.4°C ± 0.7°C using a microwave device. In experiment 2 (n = 17, 30.2 ± 9.8 yr), VL sonographic images were obtained with the knee both fully extended (0°) and flexed to 90° and EI and fascicle angle measured post hoc. Fascicle movement was tracked during the passive knee flexion to ensure that sonographic images were obtained at the same muscle region. Knee flexion reduced muscle thickness, and we therefore reran analyses calculating EI using identical dimensions to minimize this effect.

Results
EI decreased only immediately after the passive heating, and although a moderate, negative correlation was observed between EI and temperature (r
rm = −0.36), the effect of muscle temperature was small (β = 0.97 (−1.89 to −0.06) per degree Celsius, P = 0.051). Nonetheless, EI increased as fascicle angle decreased, and a large, negative correlation (r
rm = −0.85) was observed; the effect of fascicle angle on EI was large (β = 3.0 (−3.8 to −2.2) per degree, P < 0.01), and this was maintained when analyses were performed at a constant depth of the region of interest (β = 3.5 (−4.4 to −2.7) per degree, P < 0.01).

Conclusions
These findings support the hypothesis that fascicle angle meaningfully affects VL EI but provides weak evidence of a temperature effect in vivo. Thus, acute fascicle angle alterations should be accounted for in studies using EI measurements, and longer-term studies should consider whether changes in EI might be partly explained by a change in fascicle angle.
Evaluation of a new acrylic-lead shielding device for peripheral dose reduction during cone-beam computed tomography
Authors: Shimizu Hidetoshi , Sasaki Koji , Aoyama Takahiro , Iwata Tohru , Kitagawa Tomoki , Kodaira Takeshi 
Published: November 2022

Objective:To clarify the peripheral dose changes, especially in the eye lens and thyroid gland regions, using an acrylic-lead shield in cone-beam computed tomography (CBCT).Methods:The acrylic-lead shield consists of system walls and a system mat. The radiophotoluminescence glass dosemeter was set on the eye lens and thyroid gland regions on the RANDO phantom. The system mat was laid under the RANDO phantom ranging from the top of the head to the shoulders, and then, the system walls shielded the phantom’s head. Additionally, the phantom was covered anteriorly with a band that had the same shielding ability as the system mat to cover the thyroid gland region. Protocols for CBCT imaging of the thoracic or pelvic region in clinical practice were used. The measurement was performed with and without the acrylic-lead shield.Results:The dose to the eye lens region was reduced by 45% using the system wall. Conversely, the dose to the thyroid gland was unchanged. The use of the system mat reduced the dose to the thyroid gland region by 47%, and the dose to the eye lens was reduced by 22%. The dose to the eye lens region decreased to the background level using the system walls and mat.Conclusion:The newly proposed device using an acrylic-lead shield reduced the peripheral dose in CBCT imaging.Advances in knowledge:Attention is focused on managing peripheral dose in image-guided radiation therapy. The peripheral dose reduction using the acrylic-lead shield is a new proposal in radiotherapy that has never been studied.
Editorial
Authors: Αντωνόπουλος Νίκος 
Published: November 2022

Το θέμα του 1ου Ετήσιου Ελληνόφωνου Επιστημονικού Συνεδρίου των Εργαστηρίων που θεραπεύουν το αντικείμενο της Επικοινωνίας σε Ελλάδα και Κύπρο: Η περιβαλλοντική επικοινωνία με χρήση ήχου, εικόνας και κειμένου για τη δημοσιογραφία/ πληροφόρηση-μαρκετιγκ / πολιτισμό / εκπαίδευση.
Σκοπός του Συνεδρίου cclabs είναι να προωθήσει τον γόνιμο και δημιουργικό διάλογο ανάμεσα στα Εργαστήρια Επικοινωνίας και Ενημέρωσης ελληνικών και κυπριακών πανεπιστημίων, στα μέλη της πανεπιστημιακής κοινότητας, σε ακαδημαϊκούς επιστήμονες, ερευνητές, φοιτητές, αποφοίτους, φορείς και εκπαιδευτικούς για να ανταλλάξουν ευρύτερους προβληματισμούς και να μοιραστούν τις εμπειρίες και τα ερευνητικά τους αποτελέσματα σε διάφορες πτυχές της επικοινωνίας και ενημέρωσης μέσω της χρήσης ήχου, εικόνας και κειμένου στα γνωστικά αντικείμενα της δημοσιογραφίας, πληροφόρησης, πολιτισμού καιεκπαίδευσης. Το Συνέδριο παρέχει επίσης μια διεπιστημονική πλατφόρμα σε ερευνητές, επαγγελματίες και εκπαιδευτικούς για να παρουσιάσουν και να συζητήσουν τις πιο πρόσφατες καινοτομίες και τάσεις, προκλήσεις και λύσεις στους τομείς της επικοινωνίας και ενημέρωσης.
Cost effectiveness of Electronic Gate Keeping (EGK) system on laboratory tests demand at a rural academic hospital in Eastern Cape, South Africa: a cross sectional study
Authors: Mayekiso Zoliswa , Oladimeji Kelechi Elizabeth , Pulido-Estrada Guillermo-Alfredo , Hongoro Charles , Apalata Teke 
Published: November 2022

Background: Monitoring laboratory expenditure is crucial to ensure that laboratory services remain sustainable and affordable. In South Africa, the National Department of Health (NDoH) and its partner, the National Health Laboratory Services (NHLS) collaborated to introduce Electronic Gate Keeping (EGK) systems across the country. This study estimated the cost-effectiveness of EGK on laboratory tests requested at a rural academic hospital in the Eastern Cape province of South Africa. Methods: The methodological approach involved the use of a cross-sectional study design. For 24 months (June 2015 to May 2017), data on the number and types of laboratory tests initially requested along with those rejected because there were unnecessary was obtained. Data management and cost effectiveness analysis to estimate cost savings due to EGK on laboratory test demands were carried out using MS Excel and Stata software. There were 28 types of tests requested, of which 22 were chemical tests, two were haematological tests, and four were serological tests. Results: Out of 448 028 tests requested, 17,480 (3.9%) were rejected after being identified as unnecessary through the EGK system. This rejection rate of 3.9% generated cost savings of USD 51,967.07. The top three tests that generated the most savings were the c-reactive protein (USD 6,077.68), free thyroxine (USD 5,199.92) and hepatitis A IgM (USD 3,813.61). Conclusions: The study demonstrates that the introduction of EGK has positive spinoffs; it reduced costs, strengthened the dialogue between clinicians and pathologists allowing a platform for continuous education, teaching and learning.
Management of evidence and conflict of interest in guidelines on early childhood allergy prevention and child nutrition: study protocol of a systematic synthesis of guidelines and explorative network analysis
Authors: Sieferle Katharina , Schaefer Corinna , Bitzer Eva Maria 
Published: November 2022

Background: With the rising prevalence of allergic diseases in children, prevention of childhood allergies becomes an important public health issue. Recently, a paradigm shift is taking place in the approach to preventing allergies, and clinical practice guidelines (CPG) and food-based dietary guidelines (FBDG) play an important role in providing practitioners with the latest evidence and reliable guidance. However, concern about the methodological quality of the development of FBDGs and CPGs, including limitations in the systematic reviews, lack of transparency and unmanaged conflicts of interest (COI), reduce the trust in these guidelines. Methods: We aim to synthesize the available guidance on early childhood allergy prevention (ECAP) through a systematic search for national and international CPGs and FBDGs concerning ECAP and child nutrition (CN) and to assess the quality of the guidelines and management of COI. Additionally, we will analyse the content and the evidence base of the recommendation statements. We aim to quantify the COI in guideline panellists and explore possible associations between COI and recommendations. Through a social network analysis, we expect to elucidate ties between panellists, researchers, institutions, industry and other sponsors. Guidelines are an important tool to inform healthcare practitioners with the newest evidence, but quality and reliability have to be high. This study will help identify potential for further improvement in the development of guidelines and the management of COI. If the social network analysis proves feasible and reveals more information on COI in comparison to disclosed COI from the previous analyses, the methodology can be developed further to identify undisclosed COIs in panellists. Ethics and dissemination: This research does not require ethical approval because no human subjects are involved. Results will be published in international peer-reviewed open access journals and via presentations at scientific conferences.
Effectiveness of nifedipine, labetalol, and hydralazine as emergency antihypertension in severe preeclampsia
Authors: Suhaimi Donel , Novri Dhini Aiyulie , Hamidy Yulis , Savira Maya 
Published: November 2022

Background: Preeclampsia is a highly prevalent disease among pregnant women. In the event of hypertensive emergency, nifedipine, labetalol, and hydralazine are assigned as first-line therapies in preeclampsia. Further studies are needed to compare the effectiveness of these drugs to find the most cost-effective drug with minimal side effects. This study aimed to compare the effectiveness of these drugs in lowering blood pressure during hypertensive emergencies in severe preeclampsia. Methods: 60 pregnant women with severe preeclampsia were recruited in this multiple centre double-blind randomized clinical trial from May 2021 to April 2022 in Indonesia. The patients were divided equally into three groups and treated with three doses of nifedipine, labetalol, and hydralazine, respectively within one hour with 20 minutes interval. The effectiveness was measured based on systolic and diastolic blood pressures, and mean arterial pressure (MAP). The observation was carried out until five hours post-third dose administration. Results: The blood pressure was reduced significantly after the administration of the first to the third dose of each antihypertensive (p<0.05). A single dose administration, four, one, and three patients had 20% MAP reduction in nifedipine, labetalol, and hydralazine group. Three, seven, and one patient had a failure of reaching 20% MAP reduction even after receiving the third dose. The effectiveness of the drugs to achieve 20% reduction of MAP could be ranked as follows: nifedipine>labetalol>hydralazine (57.49%, 42.13%, and 40.87%, respectively) for single dose and hydralazine>nifedipine>labetalol (111.3%, 85.12%, and 90.04%, respectively) for triple dose. Conclusions: Nifedipine is the most effective drug to reduce the blood pressure when single dose administration is used, but requires more doses to further reduce the blood pressure. Hydralazine is the most effective when the drug administration is maxed up to three doses within 60 minutes with 20 minutes interval. Thai Clinical Trials Registry (TCTR): TCTR20221014007 (14/10/2022)