bluuebunny/crossref_metadata_2025_split huggingface dataset:
Powerful disciplinary boundary crossing: Bernsteinian explorations of the problem of knowledge in interdisciplinarity
Authors: Hu Xuelong 
Published: December 2022

AbstractThis paper makes a theoretical contribution to the discussion of interdisciplinary knowledge in curriculum and research. As a challenge to much of the Mode 2 thesis concerned only with the importance of knowledge being socially relevant, this paper demonstrates how a Bernsteinian approach to interdisciplinarity relates to the internal configurations underpinning interdisciplinary knowledge. Inspired by explorations of Bernsteinian communities, this paper sets out to conceptualize the socio‐epistemic constraints under which powerful disciplinary boundary crossing occurs. The major claim is that the boundaries between disciplines and between them and the field of practice, are essential for boundary crossing. The interdisciplinary efforts do not necessarily involve diminishing disciplinary boundaries, but they are vulnerable to external weakening when there is little connection to the disciplinary core that provides stable internal norms. This paper adds to the discussion by suggesting alternatives to interdisciplinary integration, which do not require a background intellectual consilience between disciplines. It presents an appeal for a form of interdisciplinarity that is pursued to a practical end within refining disciplinary conceptual models, without invoking exaggerated claims for ‘relevance’, and with no need for a more complex edifice for crossing the established borders between disciplines.
Age of information analysis for internet of things information status update system with cellular backhaul and dedicated energy harvesting beacons
Authors: Hao Zhenchao , Jia Xiangdong 
Published: December 2022

SummaryThe Internet of Things (IoT) that is usually deployed with the assistance of cellular backhaul and energy harvesting (EH) is characterized by the status update freshness. However, the traditional nature EH results in the loss of information freshness due to the randomness of nature energy process. Although using wireless energy transferring (WET) to charge sensors can overcome this problem, this method has low‐energy efficiency. With these considerations, this paper proposes a novel IoT system under cellular communication scenario by simultaneously exploiting the nature EH and WET. The proposed IoT system is consisted of a cellular backhaul subsystem, a wireless EH and transferring (WEHT) subsystem, and a wireless sensor status update subsystem. The WEHT subsystem employs the dedicated power beacons harvesting energy from natural energy source and transferring the harvested energy to sensor. For the proposed IoT system, this paper first investigates the WEHT subsystem and constructs the Markov Chain (MC) of discrete energy states as well as the MC state transition matrix. Second, the average AoI and peak AoI (PAoI) are formulated by separately considering cellular backhaul and EHTBs. The AoI (PAoI) comparison shows that the proposed EHTB‐based IoT system can outperform the conventional non‐EHTB one where the sensor directly harvests energy from natural source. At the same time, the numerical results exploit the impact of system parameters on AoI and PAoI, respectively. It is found that there exists a trade‐off between the nature energy arrival and EHTB energy transfer so that the average minimum AoI and PAoI are achieved.
Structural Information Modeling – Die digitale Transformation der Bauwerksdiagnostik
Authors: Schacht Gregor , Fritsch Christina , Voigt Chris , Ewert Eric , Arndt Ralf 
Published: December 2022

AbstractBauwerksdiagnostische Untersuchungen sind die Voraussetzung für eine verlässliche Bewertung von bestehenden Tragwerken. Häufig fehlen konkrete und realistische Informationen über den tatsächlichen Bauwerkszustand und damit die Eingangsgrößen für die rechnerische Nachweisführung. Anders als bei Neubauten müssen diese Annahmen nicht geschätzt und durch zusätzliche Sicherheitselemente abgedeckt werden, sondern können zuverlässig mit ihrer tatsächlichen Eigenschaft sowie Streuung am Bestandstragwerk erfasst werden. Die Bauwerksdiagnostik bietet eine Vielzahl an Möglichkeiten, den Bestand und Zustand der Materialien sowie Konstruktionen realitätsgetreu zu erkunden. Die digitale Revolution des Bauwesens bedingt neue Konzepte, mit denen es gelingt, unsere bestehenden Tragwerke wesentlich effizienter und v. a. länger nutzen zu können. Der digitale Bauwerkszwilling ermöglicht die Zusammenführung und Verknüpfung von Daten unterschiedlichster Struktur und Herkunft. Damit müssen zwangsweise auch bauwerksdiagnostische Daten konsequent digitalisiert, in solche digitalen Zwillinge integriert und in Kombination mit den weiteren Bestands‐ und Zustandsdaten für den Nutzer aufbereitet werden. Dieser methodische Ansatz des Structural Information Modeling bildet die Grundlage für eine realistischere und zuverlässigere Bewertung bestehender Bauwerke.
Endoscopic management of hemorrhagic pancreatic fluid collections: A propensity‐matched analysis
Authors: Pawa Rishi , Dorrell Robert , Russell Greg , Nguyen Madison , Clark Clancy , Mishra Girish , Pawa Swati 
Published: December 2022

AbstractObjectivesHemorrhagic pancreatic fluid collections (hPFC) are a complication of pancreatitis with an unknown influence on prognosis. Advancements in endoscopic management of PFC have improved results over their surgical and percutaneous alternatives. We performed a propensity‐matched analysis comparing clinical outcomes in hemorrhagic and non‐hemorrhagic PFC (nhPFC).MethodsFrom November 2015 to November 2021, a retrospective comparative cohort analysis was performed comparing clinical outcomes for patients with hPFC and nhPFC managed with lumen‐apposing metal stents. Propensity score matching was used to balance the two subgroups. Wilcoxon two‐sample tests were used to compare continuous variables and Fisher's exact test was used to compare categorical variables. Kaplan‐Meier method was used to estimate overall survival.ResultsFifteen patients with hPFC were matched with 30 nhPFC patients. Technical and clinical success was similar in both groups. The median length of hospitalization was 6 days in the hPFC group and 3 days in the nhPFC group (p = 0.23); however, more hPFC patients required intensive care unit admission post‐procedure (33.3% vs. 16.7%, p = 0.26). Patients with hPFC were more likely to be readmitted to the hospital within 30 days (33.3% vs. 6.7%, p = 0.032). Mortality at 3 months (13% vs 3%, p = 0.25) and 6 months (27% vs. 7%, p = 0.09) was higher in the hPFC cohort. The 1‐year survival estimate was 73.3% (standard error = 11.4) in the hPFC group and 88.9% (6.1) in the nhPFC group (p = 0.16).ConclusionsPatients with hPFC are more likely to be readmitted to the hospital within 30 days and have worse clinical outcomes.
Chronic running‐wheel exercise from adolescence leads to increased anxiety and depression‐like phenotypes in adulthood in rats: Effects on stress markers and interaction with BDNF Val66Met genotype
Authors: Jaehne Emily J. , Kent Jessica N. , Lam Nikki , Schonfeld Lina , Spiers Jereme G. , Begni Veronica , De Rosa Federico , Riva Marco A. , van den Buuse Maarten 
Published: December 2022

AbstractExercise has been shown to be beneficial in reducing symptoms of affective disorders and to increase the expression of brain‐derived neurotrophic factor (BDNF). The BDNF Val66Met polymorphism is associated with reduced activity‐dependent BDNF release and increased risk for anxiety and depression. Male and female Val66Met rats were given access to running wheels from 3 weeks of age and compared to sedentary controls. Anxiety‐ and depression‐like behaviors were measured in adulthood using the elevated plus maze (EPM), open field (OF), and forced swim test (FST). Expression of BDNF and a number of stress‐related genes, the glucocorticoid receptor (Nr3c1), serum/glucocorticoid‐regulated kinase 1 (Sgk1), and FK506 binding protein 51 (Fkbp5) in the hippocampus were also measured. Rats given access to running wheels developed high levels of voluntary exercise, decreased open‐arm time on the EPM and center‐field time in the OF, reduced overall exploratory activity in the open field, and increased immobility time in the FST with no differences between genotypes. Chronic exercise induced a significant increase in Bdnf mRNA and BDNF protein levels in the hippocampus with some of these effects being genotype specific. Exercise decreased the expression of Nr3c1 and Sgk1, but increased the expression of Fkbp5. These results suggest that chronic running‐wheel exercise from adolescence increased anxiety and depression‐like phenotypes in adulthood, independent of BDNF Val66Met genotype. Further studies are required to confirm that increased indices of anxiety‐like behavior are independent from reduced overall locomotor activity.
12S gene metabarcoding with DNA standard quantifies marine bony fish environmental DNA, identifies threshold for reproducible detection, and overcomes distortion due to amplification of non‐fish DNA
Authors: Stoeckle Mark Y. , Ausubel Jesse H. , Coogan Michael 
Published: December 2022

AbstractSingle‐species PCR assays accurately measure eDNA concentration. Here we test whether multi‐species PCR, that is, metabarcoding, with an internal standard can quantify eDNA of marine bony fish. Replicate amplifications with Riaz 12 S gene primers were spiked with known amounts of a non‐fish vertebrate DNA standard, indexed separately, and sequenced on an Illumina MiSeq. Fish eDNA copies were calculated by comparing fish and standard reads. Relative reads were directly proportional to relative DNA copies, with average and maximum variance between replicates of about 1.3‐ and 2‐fold, respectively. There was an apparent minimum threshold for consistent amplification of about 10 eDNA copies per PCR reaction. The internal DNA standard corrected for suppression of fish read counts due to amplification of non‐fish DNA. To assess potential PCR bias among species, we compared reads obtained with Riaz 12 S primers to those with modified MiFish primers, which target a different 12 S gene segment. Our results provide evidence that Riaz 12 S gene metabarcoding with an internal DNA standard quantifies marine bony fish eDNA over a range of about 10–5000 copies per reaction, without indication of significant PCR bias among teleost species. In mid‐Atlantic coastal samples, eDNA rarity was the main limitation to reproducible detection and quantification, and this was partly overcome by increasing the amount of a DNA sample amplified. Our findings support incorporating a DNA standard in 12 S metabarcoding to help quantify eDNA abundance for marine bony fish species.
Endogenous secretory leukocyte protease inhibitor inhibits microbial‐induced monocyte activation
Authors: Nugteren Sandrine , Simons‐Oosterhuis Ytje , Menckeberg Celia L. , Hulleman‐van Haaften Danielle H. , Lindenbergh‐Kortleve Dicky J. , Samsom Janneke N. 
Published: December 2022

AbstractIn the intestine, epithelial factors condition incoming immune cells including monocytes to adapt their threshold of activation and prevent undesired inflammation. Colonic epithelial cells express Secretory Leukocyte Protease Inhibitor (SLPI), an inhibitor of NF kappa light chain enhancer of activated B cells (NF‐κB) that mediates epithelial hyporesponsiveness to microbial stimuli. Uptake of extracellular SLPI by monocytes has been proposed to inhibit monocyte activation. We questioned whether monocytes can produce SLPI and whether endogenous SLPI can inhibit monocyte activation. We demonstrate that human THP‐1 monocytic cells produce SLPI and that CD68+ SLPI‐producing cells can be detected in human intestinal lamina propria. Knockdown of SLPI in human THP‐1 cells significantly increased NF‐κB activation and subsequent C‐X‐C motif chemokine ligand 8 (CXCL8) and TNF‐α production in response to microbial stimulation. Reconstitution of SLPI‐deficient cells with either full‐length SLPI or SLPI lacking its signal peptide rescued inhibition of NF‐κB activation and cytokine production, demonstrating that endogenous SLPI inhibits monocytic cell activation. Unexpectedly, exogenous SLPI did not inhibit CXCL8 or TNF‐α production, despite efficient uptake. Our data argue that endogenous SLPI can regulate the threshold of activation in monocytes, thereby preventing activation by commensal bacteria in mucosal tissues.
Two‐Dimensional (2D) Porous Zinc Oxides Derived from the Coordination Polymer via Chemical‐Assisted Phase Transition
Authors: Lee Junhyung , Sung Lee Jun 
Published: December 2022

AbstractTwo‐dimensional (2D) porous zinc oxides (ZnO) were successfully prepared via chemical treatment and thermal annealing of coordination polymers (CPs) precursors consisting of Zn(II) ion and fumarate ligand. The morphology, crystalline phase, chemical state, and surface area of the resultant ZnO were characterized. It is experimentally discovered that the crystal phase of the CP bearing Zn(II) ions is transformed to the zinc hydroxide crystal phase by chemical treatment using ammonia water. The prepared CP‐derived porous 2D ZnO exhibited enhanced photocatalytic efficiency for dye degradation under black‐light irradiation (365 nm) compared to CP‐derived non‐porous ZnO without a chemical‐assisted phase transition process.
Assembled Porphyrin‐Based Multinuclear Ruthenium(II)‐NNNN Complex Catalysts for Transfer Hydrogenation of Ketones
Authors: Liu Tingting , Wang Qingfu , Wang Liandi , Wu Kaikai , Yu Zhengkun 
Published: December 2022

AbstractMultinuclear porphyrin‐based ruthenium(II)‐NNNN complexes were efficiently assembled by means of coordinatively unsaturated 16‐electron mononuclear ruthenium(II)‐pyrazolyl‐imidazolyl‐pyridine complex, zinc(II) meso‐tetra(4‐pyridyl)‐porphyrin (ZnTPyP), and 4,4′‐linked bipyridines. The resultant multinuclear (Ru4 and Ru8) porphyrin‐based ruthenium(II)‐NNNN complexes exhibited exceptionally high catalytic activity at as low as 0.008 mol % Ru loading for the transfer hydrogenation reaction of ketones in refluxing 2‐propanol, reaching up to 99 % yields and 5.7×106 h−1 TOFs.
Cross‐Batch Contamination in a Continuous Horizontal Decanter Centrifuge during Virgin Olive Oil Production
Authors: Guerrini Lorenzo , Corti Ferdinando , Masella Piernicola , Calamai Luca , Angeloni Giulia , Spadi Agnese , Zanoni Bruno , Parenti Alessandro 
Published: December 2022

AbstractCross‐batch contamination in a decanter centrifuge during virgin olive oil production cannot be avoided using current technology. The extent of this contamination is investigated using industrial‐scale tests, by measuring the volatile profile and color on three consecutive oil batches, collected at the decanter outlet at different extraction times. The extent of contamination varied, pointing out qualitative consequences, as defective molecules are found. The latter are often active at low concentrations, and the measured cross‐batch contamination can lead both to the downgrading of large batches of virgin olive oils and to the adulteration of monovarietal and certified productions. An innovative method, based on the direct determination of the color (L and a* coordinates) of oil at the outlet of the decanter is able to identify the same compositional change point indicated by gas chromatography, and could be successfully used to mitigate the effects of cross‐batch contamination.Practical applications: An in‐line colorimetric system can be implemented at the decanter outlet to detect the point of change between different olive batches. Otherwise, the virgin olive oil exiting from the decanter at the beginning of one batch can be collected separately in order to avoid the contamination due to the previous batch.
High‐resolution melt analysis for the detection of skin/sweat via DNA methylation
Authors: Fernandez‐Tejero Nicole , Gauthier Quentin , Cho Sohee , McCord Bruce R. 
Published: December 2022

AbstractThe determination of tissue type is important when reconstructing a crime scene as skin cells may indicate innocent contact, whereas other types of cells, such as blood and semen, may indicate foul play. Up to now, there has been no specific DNA methylation‐based marker to distinguish skin cell DNA from other body fluids. The goal of this study is to develop a DNA methylation‐based assay to detect and identify skin cells collected at forensic crime scenes for use in DNA typing. For this reason, we have utilized a DNA methylation chip array‐based genome‐wide association study to identify skin‐specific DNA methylation markers. DNA obtained from skin along with other body fluids, such as semen, saliva, blood, and vaginal epithelia, were tested using five genes that were identified as sites for potential new epigenetic skin markers. Samples were collected, bisulfite converted, and subjected to real‐time polymerase chain reaction (PCR) with high‐resolution melt analysis. In our studies, when using WDR11, PON2, and NHSL1 assays with bisulfite‐modified PCR, skin/sweat amplicons melted at lower temperatures compared to blood, saliva, semen, and vaginal epithelia. One‐way analysis of variance demonstrates that these three skin/sweat markers are significantly different when compared with other body fluids (p < 0.05). These results demonstrate that high‐resolution melt analysis is a promising technology to detect and identify skin/sweat DNA from other body fluids.
The Sliding Keys on Inclined Deflecting‐cantilevers (SKID) device: Empirical and analytical sensitivity analysis with application in post‐tensioned frames
Authors: Zhang Yichen , De Risi Raffaele , Alexander Nicholas A. 
Published: December 2022

AbstractPreviously, the authors presented a new theoretical energy dissipating technology termed a Frictional Sliding on a Sprung Slope (FSSS) device. Its purpose was to provide significant energy dissipation to post‐tensioned (PT) frames structures. The FSSS device has a triangular‐shaped hysteretic curve, which has a zero‐force activation threshold. This enables activation for any earthquake magnitude and provides progressively greater energy dissipation with an increase in structural oscillations. In addition, it is designed to allow full self‐centring of the PT framed structure. In this paper, a physical prototype FSSS is designed, constructed and experimentally tested. The prototype replaces the theoretical springs, bearings and the constraints with pairs of cantilever bars. Consequently, it is renamed a Sliding Keys on Inclined Deflecting‐cantilever (SKID) device. Six scaled SKID configurations having different manufacturing parameters were built and tested. Also, five materials were used to investigate the sensitivity to the friction coefficient of the sliding pads. Both cyclic and fatigue tests were conducted to assess SKID performance empirically. A finite element model of SKID was then implemented in OpenSees and benchmarked against the experimental results. More than 700 one‐story one‐bay PT frames with different SKID devices (PT‐SKID frames) were numerically tested to investigate the dynamic characteristics of the structural system affecting the seismic response. Based on the extensive experimental and numerical analyses, design suggestions are provided, and the PT‐SKID self‐centring features are discussed.
Exploring the site dependency of fragility functions in risk‐targeted design
Authors: Fox Matthew J. , O'Reilly Gerard J. 
Published: December 2022

AbstractIn the ongoing quest for improved seismic design codes, there is currently substantial focus on risk‐targeted design, which aims to achieve more uniform seismic risk across code‐compliant buildings. Such an approach has already been adopted in ASCE 7, which uses lognormal fragility functions, with a single assumed value for dispersion, to generate uniform risk spectra. One challenge to this approach is that fragility functions have been shown to vary depending on the site being considered. This article, therefore, explores the extent to which site location influences the dispersion of fragility functions through the study of inelastic single‐degree‐of‐freedom systems. Twenty‐four different sites across New Zealand are considered so that a diverse range of seismic hazard settings, including multiple tectonic region types, are examined. The resulting dispersion values for the cases examined range from 0.14 to 0.29 and they are shown to be influenced by both the spectral shape and variance of the target spectra used for ground motion selection. The study is then extended to the consideration of scenario‐based seismic risk analysis. It is shown that fragility functions derived using ground motions selected on the basis of probabilistic seismic hazard analysis are, in theory, not suitable for use in scenario‐based risk analyses. The potential ramifications of this work on other risk‐targeted design methods are also discussed. Overall, this work sheds important light on the importance and potential implications of site dependence for what concerns risk‐targeted design.
Multi‐stage cold energy recovery/utilization: A 10 MW class cold store with liquefied natural gas
Authors: Yue Jinxin , Feng Juan , Chen Jingyu , Liu Rui , Yu Chengbiao , Jiang Zhaomin , Chen Xiaoyuan , Shen Boyang , Fu Lin 
Published: December 2022

AbstractIn coastal cities, a large amount of cold energy is released into the nearby seawater during the process of regasification of liquefied natural gas (LNG) at the receiving terminal, and meanwhile, a large amount of exported and/or imported foods need to be frozen by bulk cold energy near the sea. In this paper, a new multistage cold energy recovery/utilization system is investigated to link the LNG cold energy directly to supply the coastal cold store. This design uses a realistic case in Ningbo LNG receiving station in China, and for the very first time considers how to utilize the LNG cold energy in an efficient manner regarding the technical, economic, and environmental benefits. A three‐stage LNG cold energy utilization system is designed and evaluated by considering different temperatures, pressures, and heat exchange parameters. Compared to conventional electric‐driven cold stores, the proposed multistage cold energy recovery/utilization system has a much cheaper capital cost during the initial investment stage, and also avoids the utility power consumption during the daily operation period. In the case study, from Ningbo LNG receiving station to a 10 MW class cold store, the proposed multienergy system can save the energy of 20.05 kilotons of standard coal, and the carbon emission reduction is up to 1.49 × 108 kg per year.
Implementation and reliability analysis of a new transformerless high‐gain DC‐DC converter for renewable energy applications
Authors: Malick Ifham H. , Zaid Mohammad , Samiullah Md. , Ashraf Imtiaz , Iqbal Atif , Sarwar Adil 
Published: December 2022

AbstractIn this paper, a new high‐gain quadratic boost DC‐DC converter is proposed for a DC microgrid. The converter has a voltage multiplier cell made up of switched inductors to obtain a high voltage at the output. It has a common ground and continuous input current, which makes the converter feasible for renewable energy and DC microgrid applications. The proposed topology consists of a single switch which makes the control simple. The converter achieves a gain of four times the traditional quadratic boost converter and can also operate in continuous and discontinuous conduction modes. The voltage stress across the switch and all the other passive components is less than the output voltage. The variation of voltage gain in the case of parasitic resistances is also shown. The reliability analysis of the proposed converter using Markov modeling is also presented by considering both open‐circuit and short‐circuit faults across the semiconductor devices. A 200 W prototype of the converter is also prepared and the hardware results of the converter are also presented in the paper. The converter operates at high efficiency of 96% at 100 W output power operation. The variation of reliability with different converter parameters like the duty cycle and the input voltage is also discussed in the paper. The experimental results in fault conditions are also shown.