bluuebunny/crossref_metadata_2025_split huggingface dataset:
Selective Synthesis of Functionalised Linear Aliphatic Primary Amines Using Photoredox Catalysis
Authors: Cauwenbergh Robin , Sahoo Prakash , Maiti Rakesh , Guidetti Andrea , Das Shoubhik 
Published: September 2022

Abstract
Linear aliphatic primary amines are crucial and every year, at least, millions of tonnes are required to meet this demand. Therefore, significant interest has been shown in finding new chemical routes for the synthesis of aliphatic primary amines. However, to comply with the sustainability requirements, synthetic routes using inexpensive feedstocks are highly prioritized. In this regard, the hydroaminoalkylation (HAA) reaction, i.e. functionalization of an olefin with an aminoalkyl group and a hydrogen atom across the C=C double bond, is desirable due to the wide availability and lower price of olefins. Although photoredox catalysis is already known to synthesize amines, the synthesis of linear aliphatic amines is only limited to hydroaminomethylation (HAM) reactions i.e. functionalization of an olefin with an aminomethyl group and has never been applied to the synthesis of long chain linear aliphatic primary amines. Considering this, the synthesis of functionalized linear aliphatic primary amines is demonstrated by using a novel photoredox-mediated decarboxylative hydroaminoalkylation reaction, which exhibited a wide scope with excellent yields. The strength of this method is demonstrated by drug synthesis, late-stage modifications of complex pharmaceuticals and elaborated with detailed mechanistic studies.
Structural insights into cardiolipin stabilization of yeast respiratory supercomplexes revealed byCryo-EM
Authors:   4	Corey F. Hryc1, Mallampalli Venkata K. P. S. , Bovshik Evgeniy I. , Azinas Stavros ,   5	Guizhen Fan, Serysheva Irina I. , Sparagna Genevieve C. , Baker Matthew L. , Mileykovskaya Eugenia , Dowhan William 
Published: September 2022

Abstract

Cardiolipin is a hallmark phospholipid of mitochondrial membranes. Despite established significance of cardiolipin in supporting respiratory supercomplex organization, a mechanistic understanding of this lipid-protein interaction is still lacking. To address the essential role of cardiolipin in supercomplex organization, we determined cryo-EM structures of a wild-type supercomplex (IV1III2IV1) and a supercomplex (III2IV1) isolated from a cardiolipin-lacking Saccharomyces cerevisiae mutant at 3.2-Å and 3.3-Å resolution, respectively. Phosphatidylglycerol is located in the III2IV1 supercomplex at similar positions as cardiolipin in the wild-type supercomplex. Lipid-protein interactions in the latter are different from that observed for the former that conceivably underlies the reduced stability of supercomplexes in mutant mitochondria. Our studies provide evidence that anionic phospholipids appear to nucleate a phospholipid domain at the interface between the individual complexes, which may contribute to supercomplex stability. Destabilization of supercomplex formation by phosphatidylglycerol has significant implications for Barth Syndrome patients where mitochondrial phosphatidylglycerol levels are significantly elevated.
Neck Muscle Vibration Alters Cerebellar Processing Associated with Motor Skill Acquisition and Proprioception
Authors: Tabbert Hailey , Bernadette Murphy , Ambalavanar Ushani 
Published: September 2022

Abstract
Long term changes in neck sensory feedback in those with neck pain impacts motor learning, proprioception, and cortical processing. However, it is unclear whether transient alterations in neck sensory input from vibration impact sensorimotor integration (SMI) and somatosensory processing following acquisition of a proprioceptive-based task. The purpose of this research was to determine the effects of neck muscle vibration on SMI and motor learning. 25 right-handed participants had electrical stimulation over the right median nerve to elicit short and middle latency somatosensory evoked potentials (SEPs) pre- and post-acquisition of a force matching tracking task. Following the pre-acquisition phase, controls (CONT) (n = 13, 6F) received 10 minutes of rest and the vibration group (VIB) (n = 12, 6F) received 10 minutes of 60Hz vibration on the right sternocleidomastoid and left cervical extensors. Task performance was measured 24 hours later to assess retention. Significant time by group interactions occurred for the N18 SEP peak (F (1, 23) = 6.475, p = 0.018, np2 = 0.220): where amplitudes increased by 58.74% in CONT and decreased by 21.77% in VIB and the N24 SEP Peak (F (1, 23) = 5.787, p = 0.025, np2 = 0.201): decreased by 14.05% in CONT and increased by 16.31% in VIB. Both groups demonstrated improvements in motor performance post-acquisition (F (1, 23) = 52.812, p < 0.001, np2 = 0.697) and at retention (F (1, 23) = 35.546, p < 0.001, np2 = 0.607). Group dependent changes in SEP peaks associated with cerebellar processing (N18 and N24) occurred post-acquisition suggesting differences in cerebellar-somatosensory pathways. This suggests that vibration altered proprioceptive inputs used to construct body schema.
Automatic Targetless LiDAR-Camera Calibration: A Survey
Authors: Li Xingchen , Xiao Yuxuan , Wang Beibei , Ren Haojie , Zhang Yanyong , Ji Jianmin 
Published: September 2022

Abstract
The recent trend of fusing complementary data from LiDARs and cameras for more accurate perception has made the extrinsic calibration between the two sensors critically important. Indeed, to align the sensors spatially for proper data fusion, the calibration process usually involves estimating the extrinsic parameters between them.Traditional LiDAR-camera calibration methods often depend on explicit targets or human intervention, which can be prohibitively expensive and cumbersome. Recognizing these weaknesses, recent methods usually adopt the autonomic targetless calibration approach, which can be conducted at a much lower cost. This paper presents a thorough review of these automatic targetless LiDAR-camera calibration methods. Specifically, based on how the potential cues in the environment are retrieved and utilized in the calibration process, we divide the methods into four categories: information theory based, feature based, ego-motion based, and learning based methods. For each category, we provide an in-depth overview with insights we have gathered, hoping to serve as a potential guidance for researchers in the related fields.
Air frying as a heat pre-treatment method for improving the extraction and yield of canolol from canola seeds
Authors: Fadairo Olamide S. , Nandasiri Ruchira , Eskin N. A. Michael , Aluko Rotimi E. , Scanlon Martin G. 
Published: September 2022

Abstract
Roasting of canola seeds prior to oil extraction is essential for producing unique flavors and heat-induced formation of novel phenolic compounds. This study investigated the efficacy of air frying as a seed roasting pre-treatment technique to improve the recovery of canolol and other oil-soluble sinapic acidic derivatives (SADs) from canola seeds. Air frying of canola seeds was carried out at temperature-time regimens of 160, 170, 180 or 190 ◦C for 5, 10, 15, or 20 min, respectively. Oil was extracted by the Soxtec method and the soluble SADs were extracted from the oil by addition of an equal volume of hexane/70% methanol mixture followed by quantification using high performance liquid chromatography-diode array detection (HPLC-DAD). The total phenolic content (TPC) and antioxidative activity of the oils were also evaluated. The results indicated a time-temperature association for the recovery of canolol. The optimum air frying condition at 190 oC for 15 min produced the maximum yield of canolol (1439 ± 45.6 μg/100 g roasted seed) in addition to other unidentified SADs. The oil extracts obtained from canola seed roasted at 180, 15 min, 190 oC, 15 and 20 min showed the highest TPC (0.387 ± 0.015, 0.413 ± 0.002 and 0.419 ± 0.002 mg GAE/g oil), respectively, and the strongest antioxidant activities (DPPH radical scavenging and iron reducing), but exhibited weak metal ion chelating activity. There was a strong positive correlation of canolol content to the antioxidant activities (DPPH, FRAP) and TPC value for the canola oil extracts (r=0.85, r=0.93 and 0.88), respectively.
Gallium isotope fractionations between several important Gallium- bearing minerals and aqueous solutions
Authors: Zhang Jixi 
Published: September 2022

Abstract
This study predicts the equilibrium isotope fractionation factors for some important Ga-bearing species, including major minerals, aqueous solutions and gas phase systems. Equilibrium isotope fractionations of Ga are investigated by using first-principles quantum chemistry method at B3LYP/6-311+G(d) level. The isotope fractionation factors of minerals Orthoclase, Albite, Quartz, Kaolinite, Forsterite, Montmorillonite, Gibbsite, Cassiterite, Aragonite, Sphalerite and Calcite are calculated with the method of the volume variable cluster model (VVCM). The 1000ln(RPFR)s of these minerals decrease in the following order: Orthoclase>Albite>Quartz>Kaolinite>Forsterite>Montmorillonite>Gibbsite>Cassiterite>Aragonite>Sphalerite>Calcite. The solvation effect of Ga3+-bearing aqueous species is modeled by the water-droplet method. The 1000ln(RPFR)s of Ga3+-bearing aqueous species decrease in the order of [Ga(OH)4]->[Ga(OH)3]>[Ga(OH)]2+>[Ga(OH)2]+>[Ga(H2O)6]3+. The calculation results show that equilibrium isotope fractionations of Ga between different minerals, solutions and gas phases are appreciable. Among solid minerals, gallium isotope fractionation has the largest value between orthoclase type and calcite type minerals. Ga isotopic fractionation value between these two minerals can reach 3.18 per mil at 100 °C. Ga isotope fractionation between Ga-bearing aqueous species and minerals are important to give some information about the different geochemistry processes such as surficial geochemistry. This study has provided those important Ga isotope fractionation factors.
MARKERS OF LOW-GRADE INFLAMMATION IN PATIENTS WITH ACUTE CORONARY SYNDROME AND 2 TYPE DIABETES MELLITUS
Authors: Bondareva O. O. , Fedorov S. V. 
Published: September 2022

Cardiovascular diseases cause approximately one-third of all deaths in the world, of which 7.5 million deaths are estimated to be due to ischemic heart disease (IHD). Acute coronary syndromes (ACS) and sudden death cause most IHD-related deaths, which represent 1.8 million deaths per year. Established, that patients with diabetes mellitus (DM) are more likely to experience of ACS and heart failure and are at greater risk for dying after an acute cardiac event, than patients without diabetes.
The purpose of this study is evaluation of leukocyte and its populations count, leukocytes indices and plasma level of high sensitive C-reactive protein (hsCPR) in patients hospitalized due to ACS with or without of 2 type DM.
Material and Methods. We observed of 124 patients with ACS which were randomized into two groups: 1st group – 93 patients with ACS and DM; 2nd group – 31 patients with ACS without 2 type DM. 30 apparently healthy persons were included into control group. We studied of leukocytes count and their subpopulations in blood; calculated of their subpopulation indices: neutrophils to lymphocytes ratio (NLR), neutrophils to monocytes ratio (NMR), neutrophils to lymphocytes+monocytes ratio (N/LMR), lymphocytes to monocytes ratio (NMR) at admission. The plasma levels of hs-CRP were detected by ELISA method.
Results of study. The significant increase of white blood cells count and neutrophils count in patients with ACS at admission was detected in our study, especially in cases with DM. On the contrary, the counts of lymphocytes were decreased in patients with ACS and ACS with 2 type DM, versus data in control group. In patient with ACS the increased parameter of NMR was observed (p<0.001). Similarly, the following indices were higher, compared with control group parameters: NLR – for 3.32 times (in patients with ACS and DM) and for 2.43 times (in patients with ACS and without DM) (p<0.001); N/LMR – for 2.98 times (in patients with ACS and DM) and for 2.14 times (in patients with ACS and without DM) (p<0.001). On the contrary, LMR was decreased in both groups of patients with ACS – for 1.4 times and 1.36 times, respectively (p<0.05). The increased plasma levels of hs-CRP were detected in patients with ACS, more significant – in case of 2 type DM (fig. 1): for 2.1 times and for 2.59 times, respectively (p<0.001).
Conclusion. ACS is characterized of raised white blood cells and neutrophils count and low lymphocyte count, especially in cases of association with 2 type Diabetes Mellitus. Low-grade inflammation in patients with ACS and DM caused of increased levels of hs-CRP and some leukocyte ratios: NMR, N/LMR, NLR.
STUDY OF THE DYNAMICS MORBIDITY OF THE POPULATION OF THE CARPATHIAN REGION FOR SYSTEMIC TICK BORELIOSIS (LYME DISEASE)
Authors: Stefurak V. P. , Dovhanych N. V. , Kishchuk S. M. 
Published: September 2022

The distribution and dynamics of natural-mediated zoonosis (Lyme disease) in the Carpathian region have been studied and measures for its prevention have been developed. It is established that the vectors of Lyme disease are Ixodes mites. The disease is transmitted transmissible through the adhesion of Ixodes mites to the human body. In mites, transovarian (through eggs) and transphase (through larvae and nymphs) transmission of pathogens.
The data obtained indicate that the incidence of Lyme disease in mountainous populations is high. The trend in the incidence of the population is growing from year to year, in particular in Kosiv, Verkhovyna and Rakhiv districts. The disease mainly affects people of active age, more often representatives of professional risk groups (foresters, berry and mushroom pickers, shepherds, hunters, etc.)
Na początku był Kijów
Authors: Wieczorek Anna 
Published: September 2022

W dniu 24 lutego 2022 r. Federacja Rosyjska rozpoczęła na terytorium Republiki Ukrainy „operację specjalną”. Przytłaczająca większość państw nazwała to wojną, niesprowokowaną przez Ukrainę i jak dotychczas niewypowiedzianą przez Rosję. Żeby próbować zrozumieć skomplikowane relacje Rosji i Ukrainy trzeba prześledzić ich dzieje. Zarówno Federacja Rosyjska, jak i Ukraina odwołują się do wspólnych korzeni, którymi była Ruś Kijowska, potężny organizm państwowy w okresie od IX do połowy XII w. Obydwa państwa są następcami prawnymi ZSRR i uważają, że to im należą się Krym i tereny nad Morzem Azowskim. Celem artykułu jest pokazanie zmian w przynależności państwowej terytorium Republiki Ukrainy oraz przedstawienie procesów, w wyniku których doszło do ukształtowania jej granic. Słowa kluczowe: Ukraina, Ruś Kijowska, terytorium, granice, operacja specjalna
Use of an Interactive Obesity Treatment Approach in Individuals With Severe Mental Illness: Feasibility, Acceptability, and Proposed Engagement Criteria
Authors: Nicol Ginger , Jansen Madeline , Haddad Rita , Ricchio Amanda , Yingling Michael D , Schweiger Julia A , Keenoy Katie , Evanoff Bradley A , Newcomer John W 
Published: September 2022

Background
Digital and mobile health interventions are increasingly being used to support healthy lifestyle change, including in certain high-risk populations such as those with severe mental illnesses (SMIs). Life expectancy in this population lags 15 years behind counterparts in the general population, primarily due to obesity-related health conditions.

Objective
We tested the feasibility and usability of a 12-week interactive obesity treatment approach (iOTA) to adults with chronic SMIs (depression, bipolar disorder and schizophrenia spectrum disorder) receiving treatment in community settings. The iOTA incorporates short message service (SMS) text messages to supplement monthly in-person health coaching.

Methods
Factors hypothesized to be associated with weight change were illness severity and treatment engagement. Severe psychiatric symptoms were defined as baseline Clinical Global Impression severity score of >5. Criterion engagement was defined as a text messaging response rate >80% during the first 4 weeks of treatment. Disordered eating, assessed with the Loss of Control Over Eating Scores, was also evaluated. Participants provided qualitative data, further informing assessment of intervention feasibility, usability, and acceptability.

Results
A total of 26 participants were enrolled. The mean age was 48.5 (SD 15.67) years; 40% (10/26) were Black and 60% (15/26) female. Participants with lower symptom severity and adequate engagement demonstrated significantly decreased weight (F1,16=22.54, P<.001). Conversely, high symptom severity and lower text message response rates were associated with trend-level increases in weight (F1,7=4.33, P=.08). Loss-of-control eating was not observed to impact treatment outcome. Participants voiced preference for combination of live health coaching and text messaging, expressing desire for personalized message content.

Conclusions
These results demonstrate the feasibility of delivering an adapted iOTA to SMI patients receiving care in community settings and suggest testable criteria for defining sufficient treatment engagement and psychiatric symptom severity, two factors known to impact weight loss outcomes. These important findings suggest specific adaptations may be needed for optimal treatment outcomes in individuals with SMI.
Keanekaragaman Makrozoobentos Di Perairan Pusat Laut Kecamatan Banawa Kabupaten Donggala Serta Pemanfaatannya Sebagai Media Pembelajaran
Authors: Azimah Nur , Bustamin Bustamin , Nurdin Musdalifah , Zainal Syech 
Published: September 2022

Penelitian ini bertujuan untuk 1) Untuk menggambarkan keanekaragaman jenis makrozoobentos di Perairan Pusat Laut Kecamatan Banawa Kabupaten Donggala 2) Untuk menjadikan hasil penelitian sebagai media pembelajaran dalam bentuk buku saku. Penelitian ini adalah penelitian Deskriptif kuantitatif dengan tehnik pengambilan sampel menggunakan teknik purposive sampling. Indeks keanekaragaman jenis dihitung menggunakan rumus Shannon-Winner. Jenis Makrozoobentos yang ditemukan sebanyak 28 spesies yang terbagi atas 5 Class, 10 Ordo, 19 Family, 20 Genus dan 28 Spesies diantaranya yaitu Protoreaster multisipinus, Astropecten polycanthus, Ophiutrix janualis, Ophiutrix neredina, Macrobachium rosenbergii, Harpiosquilla raphidae, Odontodactylus scyllarus, Charybids helleri, Hemigrapsus sanguineus, Phymodius ungulates, Cerithium coralium, cerithium echinatum, Cerithium lividulum, Cerithium rostratum, Euplica festiva, Faunus ater, Tenguella granulate, Nassarius papillosus, Nassarius arcularia, Oximeris dimidiate, Epitonium clathrum, Tritia reticulate, Nerita albicilla, Nerita plicata, Nerita versicolor, Clithon ovalaniense, dan Turbo marmoratus. Indeks keanekaragaman jenis makrozoobentos di Perairan Pusat Laut Kecamatan Banawa Kabupaten Donggala secara umum 3,17 atau H’ tergolong tinggi, sedangkan hasil penelitian yang dapat dijadikan sebagai media pembelajaran berupa buku saku. Penilaian media oleh ahli isi sebesar 82 %, ahli desain 80%, dan ahli media sebesar 81,4 %, Validasi dari Kelompok Mahasiswa sebesar 82,25%. Dengan rata-rata yang diperoleh sebesar 81,41%. Media dalam bentuk saku dinyatakan sangat layak digunakan sebagai media pembelajaran.
Keanekaragaman Tanaman Obat Tradisional Di Desa Bangkir Kecamatan Dampal Selatan Kabupaten Toli-Toli Dan Pemanfaatannya Sebagai Media Pembelajaran
Authors: Halmayana Halmayana , Bialangi Mursito S. , Alibasyah Lestari MP , Kasim Amiruddin 
Published: September 2022

Penelitian ini bertujuan untuk (1) Mengetahui keanekaragaman jenis tanaman obat tradisional yang terdapat di Desa Bangkir Kecamatan Dampal Selatan dan Pemanfaatannya Sebagai Media Pembelajaran. (2) Mengetahui jenis-jenis tanaman obat tradisional apa sajakah yang digunakan masyarakat dalam kehidupan sehari-hari. (3) Mengembangkan hasil penelitian jenis-jenis tanaman obat sebagai media pembelajaran dan untuk menjadikan hasil penelitian sebagai media pembelajaran dalam bentuk poster. Adapun jenis penelitian yang digunakan dalam penelitian ini adalah deskriptif kualitatif dengan metode purposive sampling. Teknik pengambilan sampel yaitu menggunakan metode jelajah dan koleksi bebas. Hasil penelitian yang dilakukan di Desa Bangkir keseluruhan tergolong kategori sedang. Hal ini dilihat dari hasil nilai keanekaragaman berkisar dari 2,081-2,932. Dengan nilai rata-rata dari 3 lokasi penelitian yaitu 1,084 diketahui bahwa keanekaragaman tanaman sedang.
Gestión del talento humano, calidad, competencias socioemocionales y bienestar psicológico: el reto profesionalizador de las universidades
Authors: Fulquez Castro Sandra Carina , García Hernández Luis Fernando , Vázquez García Joaquín , Zamora Alvarado Liliana 
Published: September 2022

El mundo laboral actual se ha caracterizado por ser cambiante y requerir de trabajadores creativos, entusiastas, emprendedores y con talante para afrontar las demandas del contexto profesional de forma exitosa. El objetivo de esta investigación fue evaluar las carencias relacionadas con la gestión del talento humano a través de competencias socioemocionales, manejo del estrés y bienestar psicológico para la calidad con universitarios en formación terminal. La metodología utilizada se basó en un enfoque cuantitativo, no experimental, descriptivo y transversal. La muestra se compuso de 67 universitarios de último año de licenciatura, bajo un muestreo por conveniencia. Los instrumentos utilizados han sido un cuestionario de variables sociodemográficas creado para este estudio, la Escala de Bienestar de Ryff, la Escala Rasgo de Metaconocimiento (TMMS-24) y el Inventario SISCO de Estrés Académico. Los resultados indican que 31.34 % de los participantes no poseen habilidades para identificar y expresar adecuadamente sus emociones; 47.76 % percibe que no comprende su estado emocional. Los estresores más frecuentes identificados por los estudiantes han sidola sobrecarga de tareas (82 %) y las evaluaciones (63 %). Los síntomas psicológicos más identificados han sido la ansiedad, la angustia y la desesperación, ya que fueron reportados por 64.5 % de la muestra. En referencia al bienestar psicológico, 84.7 % afirma que no identifica tener salud física ni mental. Existe una correlación significativa (sig. = 0.03) entre las variables grado de bienestar psicológico con atención emocional (sig. = 0.03) y regulación emocional (sig. = 0.04).En conclusión, los resultados arrojaron bajos niveles de competencias socioemocionales, inadecuados estilos de afrontamientos al estrés y falta de recursos para obtener bienestar psicológico, así como una relación entre el grado de bienestar psicológico y las competencias socioemocionales.
Peningkatan Kompetensi Siswa Melalu Pelatihan Editing Video Di SMK YAPIM Biru-Biru
Authors: Sinaga Dedi Candro Parulian , Sianipar Baringin , Marpaung Preddy , Baene Stanisnicolaus , Kumar Wiknes 
Published: September 2022

Dalam Perkembangan teknologi pada saat ini media sosial hadir sebagai sarana untuk menyampaikan informasi dan komunikasi, pola informasi dan komunikasi hadir dengan berbagai format seperti berbasis teks, suara, gambar maupun video. Informasi dan komunikasi didalam media sosial banyak didominasi, sehingga kemampuan siswa dalam mengedit gambar dan video menjadi sebuah kebutuhan untuk menciptakan informasi dan komunikasi yang baik dan menarik. Pada kegiatan pengabdian kepada masyarakat di SMK YAPIM Biru-Biru ini dilaksanakan dalam bentuk pelatihan dengan tema Peningkatan Kompetensi Siswa Melalui Pelatihan Editing Video Di Smk YAPIM Biru-Biru. Pelatihan akan dilaksanakan di Sekolah SMK YAPIM Biru-Biru selama satu pekan yang dilakukan secara langsung di Laboratorium Komputer SMK YAPIM Biru-Biru. Materi yang akan disampaikan seperti Input Video, Memotong video, Input audio, Transisi efek, Kemampuan edit video dan gambar, Memisahkan