bluuebunny/crossref_metadata_2025_split huggingface dataset:
Randomized controlled trial of the Effect of General Anesthetics on postoperative recovery after minimally Invasive Nephrectomy (REGAIN trial)
Authors: Yoon Hyun-Kyu , Kim Hyerin , Yoon Susie , Seo Jeong-Hwa , Kim Won Ho , Lee Ho-Jin 
Published: March 2022

Abstract
Background: We compared the effect of general anesthetics on postoperative quality of recovery between propofol-based total intravenous anesthesia (TIVA) and inhalation anesthesia. Methods: In this randomized, single-blinded trial, 150 patients undergoing robot-assisted or laparoscopic nephrectomy for renal cancer were randomly allocated to either the TIVA or desflurane anesthesia (DES) group. Postoperative recovery was evaluated using the Korean version of the Quality of Recovery-15 questionnaire (QoR-15K) at 24 h, 48 h, and 72 h postoperatively. A generalized estimating equation (GEE) was performed to analyze longitudinal QoR-15K data. Opioid consumption, pain severity, the occurrence of postoperative nausea and vomiting, and quality of life at three weeks after discharge were also compared.Results: Data were analyzed for 70 patients in each group. The TIVA group showed a significantly higher QoR-15K score at 24 and 48 h postoperatively (24 h: DES, 96 [IQR: 77–109] vs. TIVA, 104 [IQR: 82–117], median difference 8 [95% CI: 1–15], p = 0.029; 48 h: DES, 110 [IQR: 95–128] vs. TIVA, 125 [IQR: 109–130], median difference 8 [95% CI: 1–15], p = 0.022), however not at 72 h (p = 0.400). During the entire study period, the GEE revealed significant effects of group (adjusted mean difference 6.2, 95% CI: 0.39–12.1, p = 0.037) and time (p < 0.001) on postoperative QoR-15K scores, without group-time interaction (p = 0.051). However, there were no significant differences at other time points and in other postoperative outcomes, except opioid consumption, during the first 24 h postoperatively.Conclusions: Propofol-based TIVA showed only a transient and marginal improvement in postoperative recovery compared to desflurane anesthesia, which would have been difficult to lead to significant differences in other postoperative outcomes.Trial registration: Clinicaltrials.gov, NCT04447105 (date of registration: June 25, 2020)
The surface residual stress of monocrystalline silicon in ultrasonic vibration assisted diamond wire sawing
Authors: WANG YAN , Zhao Bocheng , Li Jixing , Qian Zhaofeng , Huang Shengju , Su Jinhuan , Zhou Jing 
Published: March 2022

Abstract
Monocrystalline silicon wafer is the most important raw material in chip manufacturing, wire sawing is the most common processing method of monocrystalline silicon wafer. The residual stress generated by cutting affects the subsequent polishing costs directly, as well as the fracture strength and mechanical integrity of the monocrystalline silicon wafer, thus affecting the service performance. In this paper, the generation mechanism of residual stress was analyzed based on diamond wire sawing technology. Then, based on D-P plastic constitutive model, the magnitude and distribution of residual stress of monocrystalline silicon chip under different process parameters were simulated by ABAQUS simulation software. Finally, the experiment of ultrasonic vibration assisted diamond wire sawing monocrystalline silicon and blind hole drilling method detection were conducted, the strain values before and after drilling in three directions were measured by strain gauge rosette, and the residual stress was calculated by combining with mathematical theory, and the experimental results verified the validity of the finite element model. The experimental results showed that residual compressive stress remains on the surface of silicon wafer in both conventional wire sawing and ultrasonic vibration assisted wire sawing. The residual compressive stress increases with the increase of the axial speed of wire saw, decreases with the increase of the wire saw feed speed, and fluctuates with the increase of the workpiece rotation speed. The residual compressive stress on the surface of the silicon wafer by ultrasonic vibration assisted wire sawing is larger than that by conventional wire sawing. The variation trend of simulation and experiment results is consistent, which provides theoretical support for the subsequent processing of monocrystalline silicon wafers.
Analysis of differentially expressed genes between paroxysmal and persistent atrial fibrillation
Authors: Ning Zhongping , Wang Wenhui , Li Yao , Feng Tienan , Tian Bei , Li Xinming 
Published: March 2022

Abstract
Background This study aims to analyze the differentially expressed long noncoding RNAs and messenger RNAs (DELncRNAs and DEmRNAs) in patients with paroxysmal and persistent atrial fibrillation and explore the novel AF-related molecular mechanisms.Methods Two target datasets about paroxysmal and persistent atrial fibrillation patients (GSE75092 and GSE113013) were downloaded and further analyzed from the Gene Expression Omnibus database by R software. Upregulated and downregulated differentially expressed genes (DEGs) and the co-expressed differentially expressed genes (co-DEGs) of the two datasets were identified, of which enrichment analyses and protein-protein interaction network construction were performed. Results A total of 127 DELncRNAs and 321 DEmRNAs were screened in GSE75092; a total of 46 DELncRNAs and 64 DEmRNAs were screened in GSE113013. 8 co-DEGs were further identified in the overlap between the two datasets on Venn Diagram, which comprises 3 LncRNA and 5 mRNA. GO and KEGG analysis were successfully performed on the DEGs and co-DEGs mentioned above and the protein-protein interaction network of DEGs was constructed.Conclusions Multiple DEGs were found in patients with either paroxysmal or persistent atrial fibrillation and their functions were mainly enriched in metabolism and inflammation-related signaling pathways. The antiviral defense mechanism of PAF is an interesting difference we found.
Computational Analysis of Speed Accuracy Tradeoff
Authors: Penconek Marcin 
Published: March 2022

Abstract
Speed-accuracy tradeoff (SAT) is a well-documented phenomenon in the decision-making of humans and animals, but its underlying neuronal mechanism remains unclear. While modeling approaches conceptualize SAT through the threshold-tuning hypothesis as adjustments to the decision threshold, the leading neurophysiological perspective is the gain modulation hypothesis which postulates that the SAT mechanism is implemented through the baseline firing rate and the speed of evidence integration. In this paper, I investigate alternative computational mechanisms of SAT and show that while the threshold-tuning hypothesis is qualitatively consistent with behavioral data, the gain modulation hypothesis is inconsistent with the data. In order to reconcile the threshold-tuning hypothesis with the neurophysiological observations, I consider the interference of alpha oscillations with the decision process and show that the desynchronization of alpha oscillations results in an increase of the baseline firing rate and the speed of evidence integration. While alpha oscillations increase the discriminatory power of the decision system, they slow down the decision process. This suggests that alpha oscillations interact with the SAT mechanism and this interaction provides an alternative explanation of why the increase of the baseline firing rate and the speed of evidence integration is observed during the speed condition.
Giant Coronary Aneurysms in an Infant: Dilemma of MIS-C
Authors: Drury Alexandra , Wold Kelsey , Healan Steven , Garg Ashish 
Published: March 2022

Abstract
COVID-19 related MIS-C (Multisystem inflammatory syndrome in children) can present with cardiovascular complications like shock, arrhythmias, pericardial effusion, and coronary artery dilatation. The majority of MIS-C associated coronary artery abnormalities are dilation or small aneurysms which are transient and resolve in a few weeks[1, 2]. We present here a case of a 3-month-old child who was noted to have giant aneurysms of her coronary arteries (LAD and RCA) twenty-six days after testing positive for COVID-19. She was treated with IVIG, infliximab, and glucocorticoids along with aspirin, clopidogrel and enoxaparin. She did not show any signs of coronary ischemia or cardiac dysfunction but continued to have persistent giant coronary artery aneurysms involving the LAD (z-score ~35) and RCA (z-score ~30) [Fig. 1]. This study emphasizes the importance of early detection and aggressive management of MIS-C to prevent potentially life-threatening consequences.
Utilization of laser-induced breakdown spectroscopy, with principal component analysis and artificial neural network in revealing cheating of similarly looking fish fillets
Authors: Hamdy Omnia , Abdel-Salam Zienab , Abdel-Harith Mohamed 
Published: March 2022

Abstract
Fish is an essential source of protein and many nutrients necessary for the welfare of human health. However, the deliberate mislabeling in fish fillet types of high similarity is common in popular markets to make use of the relatively high price difference. This, of course, is a type of explicit food adulteration. Therefore, in the present work, spectrochemical analysis and chemometric methods have been adopted for disclosing this type of fish species cheating for the benefit of the customers and the market reliability. As a spectrochemical analytical technique, Laser-Induced Breakdown Spectroscopy (LIBS) has been utilized to differentiate between the fillets of the low-priced Tilapia and the expensive Nile Perch. Currently, LIBS is available for in situ measurements, namely in the markets and fish distribution centers, making it a distinguished method for such tasks compared to other conventional analytical methods. Furthermore, the acquired spectroscopic data have been analyzed statistically using principal component analysis (PCA) and artificial neural network (ANN). The obtained results demonstrated the potential of using LIBS as a simple, fast, accurate, and cost-effective analytical technique combined with a proper statistical analysis method for the decisive discrimination between fish fillets species.
Prognostic Value of Serum High Mobility Group Box 1 Protein and Histone H3 Levels in Patients with Disseminated Intravascular Coagulation: A Multicenter Prospective Cohort Study
Authors: Mori Hirotaka , Kataoka Yuki , Harada-Shirado Kayo , Kawano Noriaki , Hayakawa Mineji , Seki Yoshinobu , Uchiyama Toshimasa , Yamakawa Kazuma , Ishikura Hiroyasu , Irie Yuhei , Nishio Kenji , Yada Noritaka , Okamoto Kohji , Yamada Shingo , Ikezoe Takayuki 
Published: March 2022

Abstract
Background
We compared the prognostic value of serum high mobility group box 1 protein (HMGB1) and histone H3 levels with the International Society on Thrombosis and Haemostasis (ISTH) disseminated intravascular coagulation (DIC) scores for 28-day in-hospital mortality in patients with DIC caused by various underlying diseases.
Methods
We conducted a multicenter prospective cohort study including two hematology departments, four emergency departments, and one general medicine department in Japan, between August 2017 and July 2021. We included patients diagnosed with DIC by the ISTH DIC scoring system.
Results
Overall, 104 patients were included: 50 with hematopoietic disorders, 41 with infections, and 13 with the other diseases. The 28-day in-hospital mortality rate was 21%. The receiver operator characteristic (ROC) curve showed that a DIC score of 6 points, serum HMGB1 level of 8 ng/mL, and serum histone H3 level of 2 ng/mL were the optimal cutoff points. The odds ratios of more than these optimal cutoff points of the DIC score, serum HMGB1, and histone H3 levels were 1.58 (95% confidence interval [CI]: 0.60 to 4.17, p = 0.36), 5.47 (95% CI: 1.70 to 17.6, p = 0.004), and 9.07 (95% CI: 2.00 to 41.3, p = 0.004), respectively. The area under the ROC curve of HMGB1 (0.74, 95% CI: 0.63 to 0.85) was better than that of the ISTH DIC scores (0.55, 95% CI: 0.43 to 0.67, p = 0.03), whereas that of histone H3 was not (0.71, 95% CI: 0.60 to 0.82, p = 0.07). Calibration and net reclassification plots of HMGB1 identified some high-risk patients, whereas the ISTH DIC scores and histone H3 did not. The category-free net reclassification improvement of HMGB1 was 0.45 (95% CI: 0.01 to 0.90, p = 0.04) and that of histone H3 was 0.37 (95% CI: −0.05 to 0.78, p = 0.08).
Conclusions
Serum HMGB1 levels have the prognostic value for mortality in patients with DIC. This finding may help physicians develop treatment strategies.
Outcomes and Risk Factors for Delayed-Onset Postoperative Respiratory Failure: A Multi-Center Case-Control Study by the University of California Critical Care Research Collaborative (UC3RC)
Authors: Stocking Jacqueline C. , Drake Christiana , Aldrich J. Matthew , Ong Michael K. , Amin Alpesh , Marmor Rebecca A. , Godat Laura , Cannesson Maxine , Gropper Michael , Romano Patrick S. , Sandrock Christian E. , Bime Christian , Abraham Ivo , Utter Garth 
Published: March 2022

Abstract
Background: Few interventions are known to reduce the incidence of respiratory failure that occurs following elective surgery (postoperative respiratory failure; PRF). We previously reported risk factors associated with PRF that occurs within the first five days after elective surgery (early PRF; E-PRF); however, PRF that occurs six or more days after elective surgery (late PRF; L-PRF) likely represents a different entity. We hypothesized that L-PRF would be associated with worse outcomes and different risk factors than E-PRF.Methods: This was a retrospective matched case-control study of 59,073 consecutive adult patients admitted for elective non-cardiac and non-pulmonary surgical procedures at one of five University of California academic medical centers between October 2012 and September 2015. We identified patients with L-PRF, confirmed by surgeon and intensivist subject matter expert review, and matched them 1:1 to patients who did not develop PRF (No-PRF) based on hospital, age, and surgical procedure. We then analyzed risk factors and outcomes associated with L-PRF compared to E-PRF and No-PRF.Results: Among 95 patients with L-PRF, 50.5% were female, 71.6% white, 27.4% Hispanic, and 53.7% Medicare recipients; the median age was 63 years (IQR 56, 70). Compared to 95 matched patients with No-PRF and 319 patients who developed E-PRF, L-PRF was associated with higher morbidity and mortality, longer hospital and intensive care unit length of stay, and increased costs. Compared to No-PRF, factors associated with L-PRF included: preexisiting neurologic disease (OR 4.36, 95% CI 1.81 – 10.46), anesthesia duration per hour (OR 1.22, 95% CI 1.04 – 1.44), and maximum intraoperative peak inspiratory pressure per cm H20 (OR 1.14, 95% CI 1.06 – 1.22).Conclusions: We identified that pre-existing neurologic disease, longer duration of anesthesia, and greater maximum intraoperative peak inspiratory pressures were associated with respiratory failure that developed six or more days after elective surgery in adult patients (L-PRF). Interventions targeting these factors may be worthy of future evaluation.
Adoption of Machine Learning Technique in Nile River Islands Classification
Authors: Kamal Noha , El-Banna Ahmad A. Aziz , El-Ashmawy Nagwa 
Published: March 2022

AbstractWider adoption of machine learning methods in water resources has the potential to greatly accelerate the efficiency and quality of analysis. The Nile River is one of the major fluvial hydro-systems in the world. Fluvial islands are present in nearly all natural and regulated rivers. The Nile River is characterized by numerous natural phenomena and human interventions represented in multiple islands characteristics. This paper investigates the formation and development of the Nile River islands in the fourth reach, which extends between Assuit and Delta barrages. A machine learning (ML) technique, with the Random Forest (RF) algorithm, has been introduced as a potential technique to replace the traditional ones, to extract and classify the land cover types and the geometrical characteristics of the Nile River islands. The assessment of the results of extracting the Nile River islands and the land cover types are included. The accuracy of the extracted boundaries of the islands is assessed using field surveying data. The classification of the islands based on the islands' geometric characteristics represented that 70% of the extracted islands are classified as Wide Island, 20% are classified as Equal Island, and 10% as Narrow Island. The islands’ classification, based on the land cover, results show that there is only 5% of the islands that are urban areas, 5% of the islands are mixed class (both vegetation and urban), and the rest of the islands 90% have a vegetation land cover type. The accuracy assessment was performed using the error matrix, the results show that the overall accuracy of the land cover classification is greater than 84%. The proposed islands’ classification scheme can become an important tool that provides the decision-makers with more detailed information to improve the planning of the Nile River islands development projects. Furthermore, this schema can be expanded to other climatic and topographic regions.
Evaluation of global gridded crop models (GGCMs) for the simulation of major grain crop yields in China
Authors: Li Zhonghe , Zhan Chesheng , Hu Shi , Ning Like , Wu Lanfang , Guo Hai 
Published: March 2022

Abstract
Multimodel ensembles are powerful tools for evaluating agricultural production. Multimodel simulation results provided by the Global Gridded Crop Model Intercomparison (GGCMI) facilitate the evaluation of the grain production situation in China. With census crop yield data, the performance of nine global gridded crop models (GGCMs) in China was evaluated, and the yield gaps of four crops (maize, rice, soybean, and wheat) were estimated. The results showed that GGCMs better simulated maize yields than those of other crops in the northeast, north, northwest, east, and center. GEPIC (CLM-CROP) performed best in simulating maize (wheat) yield in the north, east, and northwest (southwest and south), due to reasonable parameter (cultivar and phenology parameters) settings. Because the rice phenology parameters were calibrated against phenological observation networks and a simple nitrogen limitation index was introduced, ORCHIDEE-CROP performed well in rice yield simulation and soybean yield simulation (center and southwest). Among four crops, wheat has the largest yield gap (7.3–14.1%), in which the poor soil of northwest (14.1%) exposes wheat to relatively high nutritional stress. Thus, in northwest China, optimizing nitrogen management in wheat production can effectively mitigate the negative impact of climate change on crop production.
Deterministic and probabilistic projections and their credibility in analyzing future precipitation variations in the Yellow River Basin, China
Authors: Sun Zhouliang , Liu Yanli , Zhang Jianyun , Chen Hua , Shu Zhangkang , Guan Tiesheng , Wang Guoqing , Jin Junliang , Bao Zhenxin , Liu Cuishan 
Published: March 2022

AbstractIt remains a key challenge to obtain reliable future precipitation estimates and their reliability under different climate scenarios. In this study, the deterministic projection of future precipitation in the Yellow River Basin (YRB) was obtained within the Bayesian model averaging (BMA) framework. A probability estimation method based on the BMA weighting scheme was proposed to obtain the probabilistic projection of precipitation. We also analyzed the credibility of these two projections. The results showed that four indexes projected by the BMA method showed an increasing trend with a higher probability. The probabilities of increasing with varying degrees were more than those for decreasing for all the precipitation indexes. The credibility of the precipitation estimation under specific climate scenarios was testified by the lower ED (the mean of long-term annual relative simulation deviation) and VD (the variance of long-term annual relative simulation deviation). The estimation based on the BMA model is more trustworthy than any other model. For the four precipitation indicators, the accuracy between the calculated VR (Variation range, to describe the interval of variation of the indicators) with the greatest likelihood and the actual VR was 38.31–53.74%. In 81.93–94.70% of grids, the deviations were smaller than one level. Both the deterministic and probabilistic projections have high geographic distribution and variation trend consistency.
Activation of hydrogen peroxide by graphite supported H2SO4-CeO2 for isoniazid degradation under neutral pH
Authors: Jiang Qihui , Qian Ruyi , Shen Tongdong , Tong Shaoping 
Published: March 2022

Abstract
Graphite felt (GF) supported cerium oxide (CeO2) composite with sulfation pretreatment (H2SO4-CeO2/GF) was prepared by the impregnation method and employed as the catalyst to activate H2O2 for degradation of isoniazid (INH). The obtained samples were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM) and X-ray photoelectron spectrum (XPS). The results showed that H2SO4-CeO2/GF had good properties in activating H2O2 for the degradation of INH. The INH removal was about 89.4% in 120 min under the following conditions: H2O2 2.94 mM, H2SO4-CeO2/GF 2.6 g/L, INH 10 mg/L, initial pH at 6.8 and temperature at 25 °C. The effects of some reaction parameters, including initial H2O2 concentration, initial INH concentration, initial pH value, the catalyst dosage and reaction temperature, on INH degradation were investigated. On the basis of mechanism study and intermediate analysis, the possible degradation pathway of INH was proposed. Besides, effective degradation of methyl orange (MO) and norfloxacin (NOF) also confirmed the high activity of H2SO4-CeO2/GF in activation of H2O2. The H2SO4-CeO2/GF was relatively stable, showing good application prospects.
Performance intensification of constructed wetland technology: a sustainable solution for treatment of high-strength industrial wastewater
Authors: Nurmahomed N. , Ragen A. K. , Sheridan C. M. 
Published: March 2022

AbstractThe objectives of this study were to: (1) assess the intensification of chemical oxygen demand (COD) and phosphate (PO4-P) removal; and (2) generate a set of rate constants of COD degradation (kCOD) and phosphate (kPO4-P) removal for the treatment of industrial wastewater (WW) using intensified adsorption beds. Two horizontal subsurface flow constructed wetlands (HSSFCWs) filled with coal ash and alum sludge and two conventional HSSFCWs packed with gravels were operated with different loadings of COD and PO4-P at a hydraulic retention time (HRT) of 24 hrs at water depth of 0.40 m. The bed performance was analysed for COD and PO4-P removal efficiency. The intensified HSSFCWs outperformed the control beds by a mean COD and PO4-P removal efficiency of 43 and 49%, respectively. The progression of COD and PO4-P removal along the system was fitted into the first-order plug flow model (K-C model). In this study the kCOD values ranged from 0.36 to 0.65 m/d with a mean of 0.46 ± 0.08 m/d (n = 30). The kPO4-P values ranged from 0.74 to 1.76 m/d and averaged to 1.23 ± 0.37 m/d (n = 30), irrespective of the condition applied. Hence, these data can be used for future projects using HSSFCWs to treat industrial wastewater.