bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reduction of Gastrointestinal Bleeding in Patients With Heyde Syndrome Undergoing Transcatheter Aortic Valve Implantation
Authors: Goltstein Lia C.M.J. , Rooijakkers Maxim J.P. , Görtjes Natasha C.C. , Akkermans Reinier P. , Zegers Erwin S. , Pisters Ron , van Wely Marleen H. , van der Wulp Kees , Drenth Joost P.H. , van Geenen Erwin J.M. , van Royen Niels 
Published: July 2022

Background:
Heyde syndrome is the co-occurrence of aortic stenosis and gastrointestinal bleeding secondary to angiodysplasias. Surgical aortic valve replacement effectively reduces bleeding, but the effects of transcatheter aortic valve implantation (TAVI) are largely unknown. This study aimed to describe the reduction of gastrointestinal bleeding in patients with Heyde syndrome after TAVI and to identify the factors associated with rebleeding.

Methods:
We enrolled patients with Heyde syndrome from a prospective TAVI registry. Gastrointestinal bleeding episodes were assessed by the Bleeding Academic Research Consortium classification, and cumulative incidence functions were used to calculate cessation rates. Factors potentially associated with rebleeding were analyzed using logistic regression. Differences between Heyde and non-Heyde patients were assessed through a case-cohort study.

Results:

Between December 2008 and June 2020, 1111 patients underwent TAVI. There were 70 patients with Heyde syndrome (6.3%). In the first year following TAVI, gastrointestinal bleeding ceased in 46 of 70 patients (62% [95% CI, 50%–74%]). Bleeding episodes decreased from 3.2 (95% CI, 2.5–4.2) to 1.6 ([95% CI, 1.2–2.2]
P
=0.001) and hemoglobin levels increased from 10.3 (95% CI, 10.0–10.8) to 11.3 (95% CI, 10.8–11.6) g/dL (
P
=0.007). Between 1 and 5 years after TAVI (35 [interquartile range, 21–51] months), 53 of 62 patients (83% [95% CI, 72%–92%]) no longer experienced gastrointestinal bleeding. Paravalvular leakage (≥mild) was associated with rebleeding risk (odds ratio, 3.65 [95% CI, 1.36–9.80];
P
=0.010). Periprocedural bleeding was more common in Heyde than in control patients (adjusted odds ratio, 2.55 [95% CI, 1.37–4.73];
P
=0.003).

Conclusions:
Patients with Heyde syndrome are at increased risk for periprocedural bleeding. Post-TAVI, gastrointestinal bleeding disappears in the majority of patients. Paravalvular leakage may curtail these clinical benefits.
Dancing with Objects: A Psychological and Neurophysiological Analysis
Authors: Boucher Marc 
Published: July 2022

AbstractThis article uses the psychological concept of body schema and the neurophysiological notion of peripersonal space to discuss the phenomenon of dancing bodies that wear, handle, and share objects. The author shows the complex and dynamic relationship between body and object to be central to the experience of dancing with objects, which is investigated in terms of multisensory integration, most notably in relation to proprioceptive, haptic, and tactile perception. It is posited that, although stemming from different theoretical approaches, both the psychological and neurophysiological perspectives demonstrate how the body incorporates and is incorporated by the things it moves with.
Inverting the Paradigm: From Art to Granular Science
Authors: Leighton Benjamin , Guillard François , Perez Karin Einav , Einav Itai 
Published: July 2022

Abstract
The interface between art and science is an increasingly recognized source of innovation, yet explorations tend to skew toward art reaping the benefits of scientific developments. While, today, art is often freely embraced within scientific fields, it is rarely afforded the freedom to transform scientific research. The authors explore a new paradigm of “art-inspired science” by reimagining and computationally simulating an existing artwork as a dynamic body of cohesive particles. In the process, hanging forms of “granular stalactites” are identified and subsequently reproduced in an idealized simulated system. A theoretical “stickiness” model was then developed to predict their maximum height, which could have wide technological application. Artworks may therefore serve as catalysts for distinctive scientific research, allowing a mutually productive relationship between the disciplines.
Realism in the Age of the Simulated Image: Two Black Holes
Authors: Nelson Peter 
Published: July 2022

Abstract
This paper examines the production and reception of two scientific images of black holes, the 2019 image of the M87 black hole and Gargantua from Christopher Nolan’s 2014 film Interstellar. The author argues that these two images of unobservable phenomena crystallize a definition of contemporary realism. In an information-rich society a simulated image achieves realism by compressing large amounts of data into an intelligible image using an algorithmic methodology that the viewer trusts as scientifically reliable and therefore realistic.
Signal to Noise Loops: A Cybernetic Approach to Musical Performance with Smart City Data and Generative Music Techniques
Authors: Roddy Stephen 
Published: July 2022

AbstractThis article introduces the Signal to Noise Loops project, which consisted of a series of performances and installations that took place worldwide between 2017 and 2022. The project utilized open data from a network of Internet of Things sensors placed around Dublin, Ireland, in the context of experimental music performance and composition. This network was underpinned by a theoretical framework from the field of cybernetics that united and integrated methods and approaches from the wide-ranging fields of data-driven music, generative music, rhythm analysis, and smart cities research.
Mapping the Field of Sound Art: René Block’s Diagrammatic Modernism
Authors: Rosati Lauren 
Published: July 2022

Abstract
The author examines a series of diagrams produced by gallerist René Block in the 1980s that aimed to provide a genealogy for the nascent field of sound art. She assesses the broad narratives presented in these schematics and the people and practices omitted. She then compares them to other modernist diagrams, including Alfred H. Barr Jr.’s 1936 chart for the Museum of Modern Art asserting the trajectory of abstraction. Finally, she measures Block’s diagrams against today’s expanded field of sound art.
Is the Pope’s Hope Being Dashed?
Authors: Nche George C. , Nortjé-Meyer Lilly (SJ) , Blanc Julia , Uwaegbute Kingsley I. 
Published: July 2022

Abstract
At the height of the deadlocks around global climate change discussions and negotiations, Pope Francis made entry with a morally captivating encyclical letter (Laudato Si) on the Care for Creation. Using a scoping review approach, we focused on a five-year-old body of research around the encyclical, identifying impacts as well as other issues arising from the scholarly engagements. Here, 150 English written publications from 2015 to 2020 were reviewed. The majority of these texts (80 %) addressed the significance and vision of Laudato Si. The rest were distributed between those that presented criticisms of the letter (11 %) and those that gauged the impact of the letter on environmental worldviews (9 %). Second, the climate change (technological advancement)-poverty (climate justice) connection, which is the encyclical’s major focus, remains contested and inconclusive as some critics have rather found and presented a positive relationship between these variables. Third, Laudato Si has recorded a mixed impact. To some people, it has not only led to increased credibility of the Pope but also the increased concern for climate change, whereas to others, it has led to a decreased credibility of the Pope as well as a lessened concern for climate change. Fourth, studies gauging Laudato Si’s impact is geographically biased as they have largely focused on the US and Europe while neglecting other regions especially Africa. The implications of these findings for research and policy are discussed.
The Islamic Republic of Iran’s Export of Human Rights Violations through Proxies: Yemen and the Case of the Bahá’ís
Authors: Moinipour Shabnam 
Published: July 2022

Abstract
Following the 1979 Revolution, the new regime began propagating a pan-Islamic ideology in order to unify Muslims under the rule of one country, the Islamic Republic of Iran. While it succeeded in recruiting proxies for this purpose, it has yet to succeed in materializing pan-Islamism. Iran’s proxies, who are currently active in Syria, Iraq, Yemen, Lebanon, the Palestinian territories, Afghanistan, and Pakistan are not only assisting Iran to reach its strategic goal of becoming the dominant power in the Middle East, but they are also beginning to import Iran’s human rights policies. One emerging example is the case of the Bahá’ís. In recent years, the Houthis, who are Iran’s proxy in Yemen, have begun severely persecuting the Bahá’ís in that country. The Bahá’ís in Yemen make only 1 percent of the non-Muslim population but they are the most persecuted group there. What this article aims to tackle are the reasons why there is a divergence in Iran’s bilateral versus multilateral export of human rights violation policies and why the Bahá’ís are a target of the Houthis in the middle of a conflict when this proxy has been created to fight against Saudi Arabia.
A Study on Executives’ Self–Other Rater Agreement on HEXACO Personality and OCB
Authors: Soumyaja Devi , Kamalanabhan T. J. 
Published: July 2022

We tested the level of agreement between the self and other ratings for honesty–humility, emotionality, extraversion, agreeableness, conscientiousness and openness to experience (HEXACO-PI [R]) in a sample of 100 managerial executives from India, along with their co-employees. It is our endeavour to understand whether the relationship between organizational citizenship behaviour (OCB) and personality, measured through HEXACO, varies across the personality-rating source. Using a survey method comprising a 21-item questionnaire, we noted that all the six HEXACO dimensions had high and significant self–other agreement. Interestingly, the highest correlation was observed for conscientiousness, while the lowest correlation was for openness to experience. However, the relationship between HEXACO and OCB differed across different rating sources. Further, HEXACO, as rated by co-workers, did seem to have a better explanatory power than self-rated HEXACO, in predicting OCB. Importantly, the observed relationships between self and co-worker-related personality and OCB have been explained through the socio-analytic theory and the trait visibility theory. Based on our analysis, we assume that the psychometric properties of the HEXACO scale can be generalized in the Indian context. However, for work-related behaviour, personality rating by a co-worker is a better predictor than global self-rating. JEL CODE: M
Aerobic exercise for HIV-associated neurocognitive disorders in individuals on antiretroviral therapy: A randomised controlled trial
Authors: Nweke Martins , Nombeko Mshunqane , Govender Nalini , Akinpelu Aderonke , Ukwuoma Maryjane , Ogunniyi Adesola 
Published: July 2022

Introduction The increasing burden of self-limiting forms of HIV-associated neurocognitive disorder (HAND) in the antiretroviral therapy era calls for adjunctive interventions. The study aimed to determine the effects of a 12-week aerobic exercise programme on HAND. Methods This is a parallel-group, randomized controlled trial with concealed allocation and intention-to-treat analysis. This study was a clinic-based programme. Seventy-three patients with HAND were enrolled in the trial. The intervention comprised a moderate-intensity aerobic exercise, 20–60 min per session, three times per week, for twelve weeks. The control group received exercise education. Prevalence of HAND constituted the primary outcome. HAND was identified and classified following the Frascati criteria. We computed the odds ratio and number needed-to-treat to estimate the treatment effect. Results There were 73 patients (38 in exercise and 35 in control arm). Individuals in the exercise arm recorded a significantly higher reduction in working memory deficit (OR = 5.14; CI  =  2.6–10.4; NNT  =  6) but not in attention-deficit (OR = 0.31, CI  =  0.2–0.5; NNT = −5) compared to the control group at twelve-week. Reductions in attention deficit (OR = 1.55, 95 CI  =  1.0–2.4; NNT  =  5) and HAND prevalence (OR = 1.8, 95 CI  =  1.2–2.8); NNT  =  8) were significantly higher in the exercise group compared the control group at three-month. No significant between-group difference in functional independence was observed immediately after exercise (p > 0.05). Discussion The neuroprotective effects of aerobic exercise appear selective and vary with cognitive abilities impaired and aerobic capacity, with a greater change occurring with improved aerobic capacity. Conclusion Individuals with working memory and attention deficits may benefit more from moderate-intensity aerobic exercise.
The effect of apolipoprotein E gene polymorphism and Lp(a) levels on coronary artery disease with atrial fibrillation
Authors: Li Yong , Chen Lei , Shao Yameng , Zhang Min , Zhi Li , Lu Yuan 
Published: July 2022

Objective To explore the influence of apolipoprotein E ( APOE) genotypes and blood lipid metabolism on coronary artery disease (CAD) with atrial fibrillation (AF). Methods Patients with suspected CAD were consecutively enrolled and divided into groups with or without CAD and/or AF. Blood lipid levels and APOE genotypes were determined and analysed for associations with CAD and AF. Results A total of 2048 patients were included (400 patients without CAD or AF [controls], 126 patients without CAD but with AF, 1294 patients with CAD without AF, and 228 patients with CAD and AF). Age and lipoprotein (a) (Lp[a]) levels were significantly higher in patients with CAD and AF versus those with CAD without AF. Among patients with CAD, the E3/E3 genotype and ε3 allele frequencies were significantly lower in patients with AF than in those without AF, and the E4/E4 genotype and ε4 allele frequencies were significantly increased. Multivariate logistic regression revealed that increased Lp(a) levels and age were independent risk factors for AF in patients with CAD. Conclusion Among patients with CAD, those with AF had increased age, ε4 frequencies and Lp(a) levels. Age and Lp(a) levels may be independent risk factors for AF in patients with CAD.
Pediatric screen exposure and school related headache disability
Authors: Langdon Raquel , Mandel Alexandra , Cameron Mark , Pierce Emily , McCracken Emily , Strelzik Jeffrey , McClintock William , Bost James , DiSabella Marc 
Published: July 2022

Background and ObjectivesProlonged screen exposure is often cited as a trigger for pediatric headache. We present initial findings evaluating the association between adolescent screen use type, duration, and school disability.MethodsNew patients aged 12–17 years presenting to a headache clinic were screened and surveyed regarding headache characteristics, behavioral habits, school attendance, and screen utilization.Results99 adolescents (29 M, 70 F) with average age 14.8 years and average headache frequency of 17 days per month completed the survey. Patients missed an average of five full days and three partial days of school due to headaches over the 90 days prior to survey completion. No statistically significant correlation was found between type or duration of screen exposure and monthly headache frequency, school attendance, or school functioning. A small positive association was seen between increasing duration of computer use, total hours screen use, and school absenteeism. While most adolescents reported prolonged screen use (58.6%) and luminosity (64.6%) worsened headaches, no statistical difference was seen in average number of headache days per month.ConclusionsAverage monthly headache frequency in an adolescent population was not significantly correlated with type or duration of screen exposure. Further studies are needed to elucidate how screen utilization impacts school related headache disability.
5-Year Arthroscopy-Free Survivorship and Outcomes of Adolescents Undergoing Primary Hip Arthroscopy: A Comparison Between Traumatic and Atraumatic Injuries
Authors: Lee Michael S. , Paraschos Olivia A. , Jimenez Andrew E. , Owens Jade S. , Maldonado David R. , Domb Benjamin G. 
Published: July 2022

Background: There is a paucity of literature evaluating the outcomes of adolescent patients undergoing hip arthroscopy for femoroacetabular impingement syndrome (FAIS) with a discrete traumatic event related to an injury. Purpose: (1) To evaluate 5-year outcomes of adolescents undergoing hip arthroscopy for FAIS with traumatic injuries (TIs) and (2) to compare the traumatic group with a propensity-matched control group of patients with atraumatic injuries. Study Design: Cohort study; Level of evidence, 3. Methods: Data were reviewed for all adolescent patients (<18 years) undergoing primary hip arthroscopy for FAIS with a TI between November 2008 and March 2015. Patients were included if they had preoperative and minimum 5-year follow-up outcomes for the modified Harris Hip Score (mHHS), Nonarthritic Hip Score, Hip Outcome Score–Sport Specific Subscale, and visual analog scale for pain. The Patient Acceptable Symptom State (PASS), minimum clinically important difference (MCID), and maximum outcome improvement satisfaction threshold (MOIT) were also calculated for both groups. Adolescents with TI were propensity matched in a 1:2 ratio according to age at surgery, sex, and body mass index (BMI) to a control group of adolescents who reported atraumatic hip symptoms (AHSs). Survivorship was defined as having no secondary surgery on the ipsilateral hip. Results: A total of 31 patients (32 hips) with TI, out of 39 total patients (40 hips) (80%), were included with a mean follow-up time of 72.2 ± 24.1 months and age of 15.8 ± 1.3 years. The TI group demonstrated significant improvement in all patient-reported outcomes (PROs) ( P < .001) and demonstrated high rates of MCID (78.3%) and PASS (91.3%) for the mHHS. When compared with a propensity-matched control group of 64 AHS hips (57 patients), the TI group demonstrated similar rates of improvement in all PROs, as well as rates of achieving the MCID, PASS, and MOIT for all PROs; however, the TI group demonstrated significantly higher revision rates compared with controls (28.1% vs 6.3%; P = .008). Conclusion: Adolescent patients with TIs undergoing hip arthroscopy demonstrated favorable outcomes for all PROs ( P < .001) and achieved high rates of MCID (78.3%) and PASS (91.3%) for the mHHS. When compared with a propensity-matched control group of adolescents with atraumatic injuries undergoing hip arthroscopy, they achieved similar levels of improvement, postoperative scores, and clinical benefit thresholds; however, reoperation rates were higher in the TI group compared with controls.
Differentiation in Posterior Tibial Slope by Sex, Age, and Race: A Cadaveric Study Utilizing 3-Dimensional Computerized Tomography
Authors: Clinger Bryce N. , Plaster Scott , Passarelli Talia , Marshall Justin , Wascher Daniel C. 
Published: July 2022

Background: Posterior tibial slope (PTS) has recently gained increased attention for its possible role in anterior cruciate ligament and posterior cruciate ligament injury. The possible differences among age, sex, and ethnicity in PTS have not yet been reported. Purpose: To describe demographic variances of proximal tibial anatomy and to detect differences in regard to ethnicity, sex, and age. Study Design: Cross-sectional study; Level of evidence, 3. Methods: In total, 250 cadaveric specimens with full-body computerized tomography scans from the New Mexico Descendant Imaging Database were randomly selected (inclusion/exclusion criteria: older than 18 years, complete imaging of the knee without previous surgery or arthroplasty) and reviewed by 3 independent observers measuring medial posterior tibial slope (MPTS), lateral posterior tibial slope (LPTS), and global posterior tibial slope (PTS), which was calculated as the mean of the MPTS and LPTS. Individuals were evenly divided among male and female and ethnicities/races: African American/Black, Asian American, Hispanic, Native American, and White. Intraclass correlation coefficient was calculated for interobserver reliability and analysis of variance statistical testing to determine statistical significance between groups. Fisher exact test was also used to understand PTS differences among ethnicities when looking at clinically significant values for potential ligamentous injury. Results: Measurements were obtained from 250 specimens with a mean age of 49.4 years (range, 19 to 103 years). The mean PTS was 8.92° (range, –9.4° to 14.95°). Asian Americans had a 1.7° greater mean MPTS than Whites ( P = .016), and African Americans/Blacks had a 1.6° greater mean PTS than Whites ( P = .022). No difference in mean PTS was seen between age and sex. When looking at clinically significant PTS, 61 (24.4%) individuals had tibial slopes <6° or >12°, 32 (12.8%) and 29 (11.6%), respectively. Statistically significant differences were seen among ethnicities with PTS <6° ( P = .017) but not with PTS >12° ( P = .106). No sex-based differences were seen in the percentage of specimens with a PTS of >12° or <6°. Conclusion: Among ethnicities, African Americans/Blacks and Asian Americans have increased PTS in comparison with Whites. Nearly 25% of individuals have clinically significant slopes of <6° or >12°, with no difference in tibial slope among sex or age groups.