bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thomas Traherne on Punctuation
Authors: Zhelezcheva Tanya K. 
Published: October 2022

Abstract
Though Thomas Traherne’s punctuation has been harshly criticized for its idiosyncrasy, scholars have also frequently admired the stylistic effects that it creates. His punctuation is linked to baroque art and music, the use of periods to highlighting subordinate ideas, capitalization to its inability to foster figurative language, and parentheses to his writing and editing process. This essay draws attention to a related, but different, issue that has remained unaddressed: what does Traherne himself have to say about punctuation? An examination of Traherne’s works shows that Traherne’s understanding of punctuation falls into two broad categories: the complex-metaphoric and the politico-religious. His metaphoric understanding, which belongs to a long tradition, can be gleaned from his references to the oracle of Delphi’s capital letters inscription; Ficino’s translation of Plato; and Ben Jonson’s borrowing from a fourteenth-century translation of Julius Scaliger’s grammar. Traherne’s politico-religious understanding of punctuation emerges most clearly in his Roman Forgeries (1673) in which he critiques a long list of ecclesiastical sources—epistles, church canons, multi-volume works of the councils—to argue that Catholic scribes and editors used punctuation for ideological purposes: to obfuscate, hide, and forge religious doctrines. Traherne’s comments reveal that early modern readers were likely to skip over text within parenthesis and marginal annotations and to be impressed by the use of all capital letters. Traherne’s textual criticism through the lens of punctuation helps us to understand early modern reading habits as well as the history of textual editing and textual transmission.
“Deep Dark Truthful Mirror”—The Logic of Petrus Ramus and the Tragedy of Samson Agonistes
Authors: Skerpan-Wheeler Elizabeth 
Published: October 2022

Abstract
The sixteenth-century educational reformer Petrus Ramus was known for disrupting the traditional relationship between logic and rhetoric. He removed the first two of the traditional five canons of rhetoric—invention and arrangement—and assigned them to logic. Thus, to Ramus, invention became not a means of finding arguments but rather a process of uncovering truth and finding a means of inquiry into the essence of a subject. This intervention affected educators, scientists, playwrights, and poets, most notably John Milton, whose own version of Ramus’s logic was published only a year after Paradise Regained and Samson Agonistes. This chronological association suggests the possibility of a connection between Milton’s understanding of invention and the distinctive nature of the tragedy of Samson. Such a connection suggests that the tragedy represents a process of invention that goes wrong, and that the apparent victory of the Danites leads to the spiritual destruction of their hero.
Using Machine Learning to Estimate Nonorographic Gravity Wave Characteristics at Source Levels
Authors: Amiramjadi Mozhgan , Plougonven Riwal , Mohebalhojeh Ali R. , Mirzaei Mohammad 
Published: October 2022

Abstract
Machine learning (ML) provides a powerful tool for investigating the relationship between the large-scale flow and unresolved processes, which need to be parameterized in climate models. The current work explores the performance of the random forest regressor (RF) as a nonparametric model in the reconstruction of nonorographic gravity waves (GWs) over midlatitude oceanic areas. The ERA5 dataset from the European Centre for Medium-Range Weather Forecasts (ECMWF) model outputs is employed in its full resolution to derive GW variations in the lower stratosphere. Coarse-grained variables in a column-based configuration of the atmosphere are used to reconstruct the GWs variability at the target level. The first important outcome is the relative success in reconstructing the GW signal (coefficient of determination R2 ≈ 0.85 for “E3” combination). The second outcome is that the most informative explanatory variable is the local background wind speed. This questions the traditional framework of gravity wave parameterizations, for which, at these heights, one would expect more sensitivity to sources below than to local flow. Finally, to test the efficiency of a relatively simple, parametric statistical model, the efficiency of linear regression was compared to that of random forests with a restricted set of only five explanatory variables. Results were poor. Increasing the number of input variables to 15 hardly changes the performance of the linear regression (R2 changes slightly from 0.18 to 0.21), while it leads to better results with the random forests (R2 increases from 0.29 to 0.37).
What Controls the Partition between the Cold and Warm Routes in the Meridional Overturning Circulation?
Authors: Rousselet Louise , Cessi Paola , Mazloff Matthew R. 
Published: October 2022

Abstract
The origins of the upper limb of the Atlantic meridional overturning circulation and the partition among different routes has been quantified with models at eddy-permitting and one eddy-resolving model or with low-resolution models assimilating observations. Here, a step toward bridging this gap is taken by using the Southern Ocean State Estimate (SOSE) at the eddy-permitting 1/6° horizontal resolution to compute Lagrangian diagnostics from virtual particle trajectories advected between 6.7°S and two meridional sections: one at Drake Passage (cold route) and the other from South Africa to Antarctica (warm route). Our results agree with the prevailing concept attributing the largest transport contribution to the warm route with 12.3 Sv (88%) (1 Sv ≡ 106 m3 s−1) compared with 1.7 Sv (12%) for the cold route. These results are compared with a similar Lagrangian experiment performed with the lower-resolution state estimate from Estimating the Circulation and Climate of the Ocean. Eulerian and Lagrangian means highlight an overall increase in the transport of the major South Atlantic currents with finer resolution, resulting in a relatively larger contribution from the cold route. In particular, the Malvinas Current to Antarctic Circumpolar Current (MC/ACC) ratio plays a more important role on the routes partition than the increased Agulhas Leakage. The relative influence of the mean flow versus the eddy flow on the routes partition is investigated by computing the mean and eddy kinetic energies and the Lagrangian-based eddy diffusivity. Lagrangian diffusivity estimates are largest in the Agulhas and Malvinas regions but advection by the mean flow dominates everywhere.
Clinical Profile, Course and Outcomes of Male Inpatients with Mental Illness Charged with Homicide: A Chart Review from an Indian Tertiary Care Hospital
Authors: Vajawat Bhavika , Kumar Channaveerachari Naveen , Hegde Prakyath , Moirangthem Sydney , Basavaraju Vinay , Prathyusha Vasuki , Bhaskarapillai Binukumar , Math Suresh Bada , Murthy Pratima 
Published: October 2022

Background: The relationship between imprisonment and mental illness is bidirectional. The clinical outcomes of prisoners with mental illness have not been widely studied, especially in developing countries. This study was conducted to assess the same among male inpatients under judicial custody with charges of homicide. Methods: A retrospective chart review of male forensic ward inpatients admitted between January 1, 2003, and December 31, 2016, was conducted. Diagnosis in the files was based on the International Classification of Diseases (ICD)-10 criteria. The Clinical and Global Improvement—Severity (CGI-S) scale was used to measure the severity of illness. Mean CGI-S assessment was carried out at baseline, end of 1 year, 5 years, and 15 years. The data were analyzed using descriptive statistics, Friedman’s test, and Dunn’s post hoc test. Results: Schizophrenia spectrum disorders and other psychotic disorders, mood disorders, and alcohol use disorders were diagnosed in 62(49.6%), 22(17.6%), and 44(35.2%) subjects, respectively. Forty-one (32.8%) subjects had at least one readmission. The average CGI-S score for the total subjects was 5 (markedly ill) at baseline and 2 (borderline ill) at the end of their latest contact with the tertiary care hospital. For the 34 subjects (27.2%) who had follow-up information of 15 years, the average CGI-S score was 1 (normal, not at all ill) at the end of 15 years (P < 0.001). Conclusion: Clinical outcomes of prisoners with mental illness seem promising, subject to the seamless availability of services. Studies from other parts of the country are required for a more systematic understanding of the requirements of care.
Trends in Involuntary Psychiatric Hospitalization in British Columbia: Descriptive Analysis of Population-Based Linked Administrative Data from 2008 to 2018
Authors: Loyal Jackson P. , Lavergne M. Ruth , Shirmaleki Mehdi , Fischer Benedikt , Kaoser Ridhwana , Makolewksi Jack , Small Will 
Published: October 2022

IntroductionInvoluntary psychiatric hospitalization occurs when someone with a serious mental disorder requires treatment without their consent. Trends vary globally, and currently, there is limited data on involuntary hospitalization in Canada. We examine involuntary hospitalization trends in British Columbia, Canada, and describe the social and clinical characteristics of people ages 15 and older who were involuntarily hospitalized between 2008/2009 and 2017/2018.MethodWe used population-based linked administrative data to examine and compare trends in involuntary and voluntary hospitalizations for mental and substance use disorders. We described patient characteristics (sex/gender, age, health authority, income, urbanity/rurality, and primary diagnosis) and tracked the count of involuntarily hospitalized people over time by diagnosis. Finally, we examined population-based prevalence over time by age and sex/gender.ResultsInvoluntary hospitalizations among British Columbians ages 15 and older rose from 14,195 to 23,531 (65.7%) between 2008/2009 and 2017/2018. Apprehensions involving police increased from 3,502 to 8,009 (128.7%). Meanwhile, voluntary admissions remained relatively stable, with a minimal increase from 17,651 in 2008/2009 to 17,751 in 2017/2018 (0.5%). The most common diagnosis for involuntary patients in 2017/2018 was mood disorders (25.1%), followed by schizophrenia (22.3%), and substance use disorders (18.8%). From 2008/2009 to 2017/2018, the greatest increase was observed for substance use disorders (139%). Over time, population-based prevalence increased most rapidly among women ages 15–24 (162%) and men ages 15–34 (81%) and 85 and older (106%).ConclusionFindings highlight the need to strengthen the voluntary care system for mental health and substance use, especially for younger adults, and people who use substances. They also signal a need for closer examination of the use of involuntary treatment for substance use disorders, as well as further research exploring forces driving police involvement and its implications.
The Role of Dementia and Residential Service Agency Characteristics in the Care Experiences of Maryland Medicaid Home and Community-Based Service Participants and Family and Unpaid Caregivers
Authors: Fabius Chanee D. , Millar Roberto , Geil Erick , Stockwell Ian , Diehl Christin , Johnston Deirdre , Gallo Joseph J. , Wolff Jennifer L. 
Published: October 2022

In Maryland, residential service agencies deliver Medicaid Home and Community-Based Services (HCBS) to older adults with disabilities through direct care workers (e.g., personal care aides). Leveraging survey data from residential service agency administrators, linked to interRAI Home Care assessments for 1144 participants, we describe agency characteristics, and participant and family caregiver experiences by participant dementia status. Most (61.7%) participants experienced low social engagement, and roughly 10.0% experienced a hospitalization or emergency room visit within 90 days. Few (14.4%) participants were served by agencies requiring dementia-specific direct care worker training, and most were served by agencies offering supplemental services, or in which direct care workers helped with health information technology (81.2% and 72.8%, respectively). Few caregivers reported negative care experiences. Participants with dementia and those served by agencies with training and support more often reported negative care experiences. Findings lay the foundation for future longitudinal and embedded interventions within Medicaid HCBS.
Understanding Confrontations and Conflicts in West Asia: Two Excellent Studies Penetrate the Veil
Authors: Ahmad Talmiz 
Published: October 2022

Deepika Saraswat, Between Survival and Status: The Counter-Hegemonic Geopolitics of Iran(MacMillan Publishers, 2022). Pp. 212, ₹1650. Fazzur Rehman Siddiqui, Arab World in Transition and the Quest for a New Regional Order (MacMillan Publishers, 2022). Pp. 242, ₹1600.
A systematic review of the current availability of mobile applications in eyecare practices
Authors: Abdulhussein D , Abdul Hussein M , Szymanka M , Farag S 
Published: October 2022

Background There is an increasing shift towards non-communicable eye diseases (NCEDs) because of a demographic transition. Incorporation of telemedicine into everyday clinical practice is becoming increasingly popular. We sought to carry out a systematic review to look at which applications on portable devices are available for use in eyecare practices for patients with NCEDs, specifically refractive error, diabetic retinopathy, age-related macular degeneration (AMD) and glaucoma. Methods Pubmed, EMBASE, Medline, PsychInfo databases were systematically searched using keywords and MeSH terms. Eligible articles included peer-reviewed, original full text articles evaluating apps for use on portable devices aimed at patients with NCEDs. Results The initial search yielded 100 studies. Nine studies met the inclusion criteria, and an additional eight studies were identified through reference screening. Of the included studies, 29.4%% (n = 5) evaluated applications aimed for use to identify refractive errors, 35.3% (n = 6) aimed at patients with glaucoma, 23.5% (n = 4) for use by patients with AMD, 11.7% (n = 2) for the non-specific monitoring of visual acuity/fields. 76.5% (n = 13) of the studies showed that the application evaluated was an effective and reliable tool compared to clinical standards. Conclusions Portable device applications in patients with NCED have been shown to be effective. The use of these apps for patients is limited to either diagnostic or monitoring use. There is scope for apps which encompass other aspects of patient care that have been used in other specialties that may be applied to ophthalmic patients, including those with an educational aim which have a role in increasing compliance.
Analyzing opioid-use disorder websites in the United States: An optimized website usability study
Authors: He Shuhan , Shyamsundar Saishravan , Chong Paul , Kannikal Jasmine , Calvano Joshua , Balapal Neha , Kallenberg Nick , Balaji Adarsh , Ankem Amala , Martin Alister 
Published: October 2022

Background As the United States continues to tackle the opioid epidemic, it is imperative for digital healthcare organizations to provide Internet users with accurate and accessible online resources so that they can make informed decisions with regards to their health. Objective The primary objectives were to adapt and modify a previously established usability methodology from literature, apply this modified methodology in order to perform usability analysis of opioid-use-disorder (OUD)-related websites, and make important recommendations that OUD-related digital health organizations may utilize to improve their online presence. Methods A list of 208 websites (later refined) was generated for usability testing using a modified Google Search methodology. Four keywords were chosen and used in the search: “DEA-X Waiver Training”, “opioid-use-disorder (OUD) Initiatives”, “Buprenorphine Assisted Treatment”, and “Opioid-Use Disorder Websites”. Usability analysis was performed concurrently with optimization of the methodology. OUD websites were analyzed and scored on several usability categories established by previous literature. Results “DEA-X Waiver Training” yielded websites that scored the highest average in “Accessibility” (0.84), while “Opioid-Use Disorder Websites” yielded websites that scored the highest average in “Content Quality” (0.67). “Buprenorphine Assisted Treatment” yielded websites that scored the highest average across “Marketing” (0.52), “Technology” (0.89), “General Usability” (0.69), and “Overall Usability” (0.68). “Technology” and “Marketing” were the highest and lowest scoring usability categories, respectively. T-test analysis revealed that each usability, except “Marketing” had a pair of one or more keywords that were significantly different with a p-value that was equal to or less than 0.05. Conclusions Based on the study findings, we recommend that digital organizations in the OUD space should improve their “General Usability” score by making their websites easier to find online. Doing so, may allow users, especially individuals in the OUD space, to discover accurate information that they are seeking. Based on the study findings, we also made important recommendations that OUD-related digital organizations may utilize in order to improve website usability as well as overall reach.
Radiological and Clinical Outcomes comparing 2-level MIS Lateral and MIS Transforaminal Lumbar Interbody Fusion in Degenerative Lumbar Spinal Stenosis
Authors: Chong Elliot Yeung , Tong Tan Lenice Yue , Chong Christoph Sheng , Yeo William , Siang Koh Don Thong , Jiang Lei , Guo Chang Ming , Cheong Soh Reuben C. 
Published: October 2022

Study design Retrospective Cohort Study Objectives To compare early postoperative radiological and clinical outcomes between 2-level minimally invasive (MIS) trans-psoas lateral lumbar interbody fusion (LLIF) and MIS transforaminal lumbar interbody fusion (TLIF) for degenerative lumbar spinal stenosis. Methods Fifty three consecutive patients undergoing 2-level lumbar interbody fusion from L3-L5 for degenerative lumbar spinal stenosis were enrolled. Twenty four patients underwent LLIF and 29 underwent TLIF. Results Operative time and length of stay were similar between LLIF and TLIF (272.8 ± 82.4 vs 256.1 ± 59.4 minutes; 5.5 ± 2.8 vs 4.7 ± 3.3 days, P > .05), whereas blood loss was lower for LLIF (229.0 ± 125.6 vs 302.4 ± 97.1mls, P = .026). Neurological deficits were more common in LLIF (9 vs 3, P = .025), whereas persistent deficits were rare for both (1 vs 1, P = 1). For both groups, all patient reported outcomes visual analogue scale (VAS back pain, VAS leg pain, ODI, SF-36 physical) improved from preoperative to 2-years postoperative ( P < .05), with both groups showing no significant differences in extent of improvement for any outcome. Lateral lumbar interbody fusion demonstrated superior restoration of disc height (L3-L4: 4.1 ± 2.4 vs 1.2 ± 1.9 mm, P < .001; L4-L5: 4.6 ± 2.4 vs .8 ± 2.8 mm, P < .001), foraminal height (FH) (L3-L4: 3.5 ± 3.6 vs 1.0 ± 3.6 mm, P = .014; L4-L5: 3.0 ± 3.5 vs -.1 ± 4.4 mm, P = .0080), segmental lordosis (4.1 ± 6.4 vs -2.1 ± 8.1°, P = .005), lumbar lordosis (LL) (4.1 ± 7.0 vs -2.3 ± 12.6°, P = .026) and pelvic incidence-lumbar lordosis (PI-LL) mismatch (−4.1 ± 7.0 vs 2.3 ± 12.6°, P = .019) at 2-years follow-up. Conclusion The superior radiological outcomes demonstrated by 2-level trans-psoas LLIF did not translate into difference in clinical outcomes compared to 2-level TLIF at the 2-years follow-up, suggesting both approaches are reasonable for 2-level lumbar interbody fusion in degenerative lumbar spinal stenosis.
Influence of zirconia on the sintering behaviour and mechanical properties of reaction-sintered mullite-based composite ceramics
Authors: Liu Zhenying , Xie Nan , Huang Shouwu , Zhang Hanxin , Wu Chongmei , Cui Kai , Liu Yin , Zhu Hongzheng , Zhu Jinbo , Xue Changguo 
Published: October 2022

ABSTRACTHigh-performance mullite-based composite ceramics were prepared successfully using natural kaolin and alumina as raw materials and ZrO2 as an additive. The influence of sintering temperature and ZrO2 content on the sintering behaviour and mechanical properties of zirconia-toughened mullite ceramics was studied systematically. With increasing sintering temperature from 1450°C to 1560°C, the primary phases of as-sintered composite ceramics were mullite and corundum with a small amount of ZrO2, and the bulk density of the composite ceramics increased from 2.29 to 2.72 g cm–3. Furthermore, the ZrO2 phase transition promoted transgranular fracture, and ZrO2 grains were pinned at the grain boundaries, thereby enhancing the mechanical strength of the composite ceramics. Moreover, the AZS12 sample, with 12 wt.% ZrO2 and sintered at 1560°C, had the greatest flexural strength and fracture toughness of 91.6 MPa and 2.47 MPa m–1/2, respectively. Adding ZrO2 to the composite ceramics increased their flexural strength by ~37.6%.
Genetic subgroups inform on pathobiology in adult and pediatric Burkitt lymphoma
Authors: Thomas Nicole , Dreval Kostiantyn , Gerhard Daniela S. , Hilton Laura K. , Abramson Jeremy S. , Ambinder Richard F. , Barta Stefan , Bartlett Nancy L. , Bethony Jeffrey , Bhatia Kishor , Bowen Jay , Bryan Anthony C. , Cesarman Ethel , Casper Corey , Chadburn Amy , Cruz Manuela , Dittmer Dirk P. , Dyer Maureen A. , Farinha Pedro , Gastier-Foster Julie M. , Gerrie Alina S. , Grande Bruno M. , Greiner Timothy , Griner Nicholas B. , Gross Thomas G. , Harris Nancy L. , Irvin John D. , Jaffe Elaine S. , Henry David , Huppi Rebecca , Leal Fabio E. , Lee Michael S. , Martin Jean Paul , Martin Marie-Reine , Mbulaiteye Sam M. , Mitsuyasu Ronald , Morris Vivian , Mullighan Charles G. , Mungall Andrew J. , Mungall Karen , Mutyaba Innocent , Nokta Mostafa , Namirembe Constance , Noy Ariela , Ogwang Martin D. , Omoding Abraham , Orem Jackson , Ott German , Petrello Hilary , Pittaluga Stefania , Phelan James D. , Ramos Juan Carlos , Ratner Lee , Reynolds Steven J. , Rubinstein Paul G. , Sissolak Gerhard , Slack Graham , Soudi Shaghayegh , Swerdlow Steven H. , Traverse-Glehen Alexandra , Wilson Wyndham H. , Wong Jasper , Yarchoan Robert , ZenKlusen Jean C. , Marra Marco A. , Staudt Louis M. , Scott David W. , Morin Ryan D. 
Published: October 2022

AbstractBurkitt lymphoma (BL) accounts for most pediatric non-Hodgkin lymphomas, being less common but significantly more lethal when diagnosed in adults. Much of the knowledge of the genetics of BL thus far has originated from the study of pediatric BL (pBL), leaving its relationship to adult BL (aBL) and other adult lymphomas not fully explored. We sought to more thoroughly identify the somatic changes that underlie lymphomagenesis in aBL and any molecular features that associate with clinical disparities within and between pBL and aBL. Through comprehensive whole-genome sequencing of 230 BL and 295 diffuse large B-cell lymphoma (DLBCL) tumors, we identified additional significantly mutated genes, including more genetic features that associate with tumor Epstein-Barr virus status, and unraveled new distinct subgroupings within BL and DLBCL with 3 predominantly comprising BLs: DGG-BL (DDX3X, GNA13, and GNAI2), IC-BL (ID3 and CCND3), and Q53-BL (quiet TP53). Each BL subgroup is characterized by combinations of common driver and noncoding mutations caused by aberrant somatic hypermutation. The largest subgroups of BL cases, IC-BL and DGG-BL, are further characterized by distinct biological and gene expression differences. IC-BL and DGG-BL and their prototypical genetic features (ID3 and TP53) had significant associations with patient outcomes that were different among aBL and pBL cohorts. These findings highlight shared pathogenesis between aBL and pBL, and establish genetic subtypes within BL that serve to delineate tumors with distinct molecular features, providing a new framework for epidemiologic, diagnostic, and therapeutic strategies.