bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ergativity, agreement and alignment shift in Western Indo-Aryan
Authors: Chandra Pritha , D'Alessandro Roberta 
Published: December 2022

Abstract
The Western Indo-Aryan languages are known for their aspect-based split ergativity, where subjects in the perfective are marked with an ergative case and unmarked objects usually trigger verbal agreement. In this paper, we survey data from multiple languages in the area and identify patterns that indicate an ongoing ergative to nominative shift. We show that languages that initiate verbal agreement with differentially marked objects (DOM) start deviating and losing the ergative case. With the subsequent emergence of an auxiliary, the subjects also start to control agreement on T. These patterns, we claim, evolve when accusative objects trigger agreement at the vP-edge, forcing subjects to get a nominative case from T in the expanded clausal spine. Our study identifies a diachronic path, from a system where the v de facto licenses both arguments to another system with a clear division of labour between v that licenses the objects, and T that licenses the subjects.
Au Clusters Enhanced Charge Separation and Transfer in WOx/g-C3N4 Heterojunctions for Efficient NOx and Benzene Conversion
Authors: Zhang Xiao , Matras-Postolek Katarzyna , Yang Ping 
Published: December 2022

Abstract
Topics on effectively improving the photochemical CO2/benzene/NO oxidation conversion performances of g-C3N4 based materials via charge transfer and separation enhancement are still considered challenging, despite the growing popularity of applying these materials in a variety of energy conversion related applications. WOx/Au-g-C3N4 heterojunctions are synthesized using two-step thermal polymerization and solvothermal treatment methods in this paper. Small Au nanoparticles are firstly incorporated in superior thin g-C3N4 via mechano-chemical pre-reaction and two-step thermal polymerization (treated at 500 and 700°C). Enhanced photocurrent density is observed after incorporated with Au, which is also in good agreement with the photocatalytic activity (H2 generation and CO2 reduction) data. Layered WOx with abundant oxygen vacancies are further incorporated into Au-modified g-C3N4 nanosheets to form heterojunctions possessing excellent photocatalytic CO2 photo-reduction performances with CO and CH4 generation rate of 5.64 and 2.58 µmolg− 1h− 1, respectively, under full solar spectrum. The heterojunctions constructed via in-situ formation show direct Z-scheme charge transfer pathway with improved charge separation and transport efficiencies. These highly stable and recyclable hierarchical g-C3N4 hybrid nanostructures (WOx/Au/g-C3N4 heterojunctions) show outstanding conversion rate (88.1%) and selectivity (99.3%) for benzene to phenol conversion under full solar spectrum condition, as well as excellent NO removal rate (61%).
Oxidized low-density lipoprotein concentration and CBF in patients with white matter hyperintensities
Authors: Zhou Ya-jun , Zhang Man , Yu Si-qi , Li Lin-lin , Huang Chao-juan , Zhang Wei , Cao Jing , Zhou Xia , Sun Zhong-Wu , Zhu Xiao-Qun 
Published: December 2022

Abstract
Background
Oxidized low-density lipoprotein (ox-LDL), as a biomarker for atherosclerosis, is closely related to the occurrence and development of cerebrovascular diseases such as acute cerebral infarction caused by cerebral vascular stenosis. White matter hyperintensities (WMHs) of presumed vascular origin, one of the most important neuroimaging markers of cerebral small vessel disease(CSVD), is associated with inflammation and chronic cerebral ischemia.
Methoeds
: Our objective is to determine whether ox-LDL concentration was associated with the change of cerebral blood flow (CBF) in patients with WMHs. Serum ox-LDL concentration was measured among 45 healthy controls (61.89 ± 6.55 years; 58% female) and 45 WMHs patients (64.96 ± 8.88 years; 44% female). CBF was automatically segmented using arterial spin labeling(ASL)for all the subjects. Results:The findings showed that the concentration of ox-LDL was higher in WMHs patients (mean ox-LDL = 184.10 ± 28.34µg/L) compared to the healthy controls (mean ox-LDL = 166.34 ± 29.72µg/L). CBF in the right precuneus (Pcu.R),an important region in the default mode network (DMN),in the WMHs patients were noticeably lower than that in the controls. Meanwhile, there was a significant correlation between ox-LDL levels and CBF in the Pcu.R (R2 = 0.165, P = 0.006) in the WMHs patients.
Conclusions
The results showed that the CBF of Pcu.R was decreased in patients with WMHs and was correlated to ox-LDL concentration. This study suggests a new treatment idea to combine antithrombotics and antioxidants for patients with white matter hyperintensitis.
Effect of fermentation on the bioactivities of the aqueous extract of Viburnum coriaceum Blume – positive as well as negative inferences on experimental basis
Authors: Vijayakumar Vijaytha , Variyar E Jayadevi , M Haridas 
Published: December 2022

Abstract

Products of natural fermentation have been considered as appealing targets for the study of drug discovery as they were diverse and complex in structure and biological activities. Significance of fermentation in drug preparation, its physicochemical parameters and clinical evaluation were extensively studied. Present study was focusing on fermentative modifications in the biological activities of the aqueous extract of Viburnum coriaceum Blume. Fermented and unfermented extracts were compared for their bioactivities. Free radical scavenging assays were performed for antioxidant activity. In vitro trypsin and lipoxygenase assays for anti-inflammatory activity and inflammation induced cell lines were studied for anti-neuroinflammatory activity. Pilocarpine induced rat models were studied for antiepileptic activity. Phytochemical screening of the extracts that befits the investigation was performed before starting the experiments. When the antioxidant, anti-inflammatory and anti-neuroinflammatory activities were found to be enhanced by fermentation, antiepileptic activity on animal models was found diminished. Qualitative analysis revealed the increased concentration of some classes of phyto-constituents and disappearance of some others after fermentation. Analysis of results uncovered the fact that fermentation has both positive and negative implications on the extract bioactivity. Disappearance of phytoconstituents and their derivatization may be the reason behind the negative effect.
Plastome phylogenomics, biogeography, and evolutionary diversification of Lilium (Liliaceae)
Authors: Zhou Nian , Miao Ke , Liu Changkun , Jia Linbo , Hu Jinjin , Huang Yongjiang , Ji Yunheng 
Published: December 2022

AbstractBackgroundLilium(Liliaceae) is an economically important genus with great medicinal, ornamental, and edible values, however evolutionary history of the genus remains poorly understood due to the lack of robust phylogeny. Based on a large plastome data set, this study aims to recover a robust backbone phylogeny of the genus to infer its historical biogeography and evolutionary diversification. Results Complete plastomes representing 50 currently accepted species in the genusLiliumwere sampled for phylogenetic analysis, among which, plastomes representing 14 species were newly sequenced in this study. Under time-calibrated phylogenetic framework, biogeographic scenarios and evolutionary diversification ofLiliumwere explored. Phylogenetic analysis recovered a backbone phylogeny ofLilium, in which most nodes were fully supported; however, failed to resolve all intrageneric sections as monophyletic. Ancestral area reconstruction proposed that the ancestor ofLiliummight widely distribute throughout the temperate regions of the Northern Hemisphere, and has experienced multiple dispersal, extinction, and vicariance events during the evolutionary course. The rate of species diversification has sharply accelerated since the late Miocene (ca.9 Ma) and kept increasing in the Pliocene and Pleistocene. Conclusions The results suggest that ancient climatic changes and geological tectonic activities, such as the Middle Miocene Climate Optimum (MMCO), the late Miocene global cooling, as well as the successive uplift of the Qinghai-Tibetan Plateau (QTP) and the enhancement of monsoonal climate in East Asia during the late Miocene and the Pliocene, jointly shaped the distribution range and drove evolutionary radiation ofLilium. Resulted from radiative divergence and distant dispersal events, the genus may have experienced incomplete lineage sorting (ILS) and morphological convergence. The uplift of QTP and enhancement of monsoonal climate dramatically triggered radiative divergence of species, accounting for the higherLiliumspecies diversity in East Asia than in Central Asia, Europe, and North America. The findings shed light on the crucial role of the unique Neogene geological and climatic events in East Asia, such as the uplift of QTP and the establishment of monsoonal climate, in shaping the uneven distribution of plant diversity in the Northern Hemisphere.
Multivariate runoff prediction by employing decomposition techniques, sample entropy, and sequence2sequence framework utilizing spatio-temporal attention
Authors: Sibtain Muhammad , Li Xianshan , Li Fei , Shi Qiang , Bashir Hassan , Azam Muhammad Imran , Yaseen Muhammad , Saleem Snoober , Ain Qurat ul 
Published: December 2022

Abstract
The exploitation of hydropower provides cleaner, sustainable and cheaper energy contrary to fossil fuels. Therefore, hydropower offers prospects to meet the sustainable development goals of the United Nations. These benefits motivate this study to develop different models for efficient runoff prediction utilizing multivariate hydro-meteorological data. The techniques employed for this purpose include correlation analysis, time series decomposition, sample entropy (SE), and sequence2sequence (S2S) algorithm with spatio-temporal attention (STAtt). The decomposition techniques include improved complete ensemble empirical mode decomposition with additive noise (ICEEMDAN) and the maxim overlap discrete wavelet transform (MODWT). The ICEEMDAN-STAtt-S2S model reveals the best prediction results over the counterpart hybrid and standalone models in terms of statistical metrics and comparison plots. The surpassed prediction outcomes substantiate the merger of ICEEMDAN and S2S utilizing STAtt for runoff prediction. Moreover, ICEEMDAN-STAtt-S2S offers the potential for reliable prediction of similar applications, including renewable energy, environment monitoring, and energy resources management.
Traumatic dental injuries due to occupational safety accidents of adult workers in Korea: a cross-sectional study
Authors: Son Ji-Young , Han Dong-Hun 
Published: December 2022

Abstract

Background This study aimed to determine the incidence of traumatic dental injuries due to safety accidents in the workplace among Koreans using data from the National Health and Nutrition Examination Survey (KNHANES) database of the Korea Centers for Disease Control and Prevention. Methods Data from KNHANES VII and VIII conducted between 2016 and 2020 were analyzed. Of the 39,738 participants of KNHANES VII and VIII, 16,588 adults between the ages of 19–54 years who completed the questionnaire on whether they experienced traumatic dental injury due to a safety accident were included. Data on the characteristics of occupational classification according to demographic characteristics and of the traumatic dental injury due to safety-related accidents. Multiple logistic regression analysis was used to analyze the incidence of traumatic dental injuries caused by accidents according to demographic characteristics and occupational classification. The analyses were adjusted for sociodemographic characteristics and related covariates. Results Of the 16,588 participants included in the analysis, 13% experienced traumatic dental injuries and 7.3% experienced traumatic dental injuries due to accidents at work. Traumatic dental injuries were significantly higher among workers involved in manual labor. Education level had the most significant impact on the association between occupational class and incidence of traumatic dental injury at work. Among manual workers, the difference in incidence of traumatic dental injuries at work between those employed in agriculture, forestry, and fisheries, and those employed in industrial plants, machine operation, and assembly was also largely influenced by the participant’s level of education. Conclusion The results of this study show that manual workers have higher incidence of traumatic dental injury due to workplace accidents than non-manual workers, and that their level of education greatly impacts this association.
Near-unity fidelity four-dimensional speckle imaging through scattering media
Authors: Xu Yi , Ye Jianwei , Pan Tuqiang , Zheng Kanpei , Luo Zhichao , Fu Songnian , Wang Yuncai , Qin Yuwen 
Published: December 2022

Abstract
Overcoming multiple scattering and realizing multidimensional speckle imaging through a turbid medium is of vital importance in both fundamental science and applications, where multiple input multiple output information of the scattering system can be bridged by a transmission matrix. Theoretically, the input wavefront can be perfectly reconstructed by simply inverting the transmission matrix of the turbid medium. However, this deterministic method for retrieving encoded amplitude and phase information has not been experimentally demonstrated yet because both the precision of measurement for the output complex light field and the transmission matrix are quite limited. Herein, we revisit the problem of speckle imaging using the inverse transmission matrix and demonstrate a concept of multidimensional speckle imaging with near-unity fidelity. Leveraging by the precise calibration of both the output light field and transmission matrix of the strongly scattering medium, four-dimensional speckle imaging exploring the amplitude, phase and two spatial dimensions is achieved without any average or approximation, where Pearson correlation coefficient can be up to 99$\%$. To the best of our knowledge, both the achieved multiplexing dimensions and the fidelity of speckle imaging represent the state-of-the-art performance among all deterministic and deep learning methods. It is therefore anticipated that our results could immediately shed new light on various general scattering problems with multiple input multiple output and beyond.
Effects of Training for Obtaining a Teaching Post in Spain in Terms of Stress, Burnout Syndrome, Resilience and Hours of Study: Structural Equation Models
Authors: Melguizo-Ibáñez Eduardo , González-Valero Gabriel , Zurita-Ortega Félix , Ortega-Martín José Luis 
Published: December 2022

Abstract

The preparation to qualify for a permanent placement as a public teacher (civil servant) in Spain is a complex process. The aim of this study is to empirically investigate the levels of resilience, stress, the burnout syndrome and study hours of candidates preparing for the state examination to get a permanent placement in the Spanish education system in relation to different education levels and to research the effects of resilience, stress and burnout syndrome on the number of study hours spent by teacher candidates in relation to different education levels. This paper presents the results of a descriptive, comparative and non-experimental investigation with a sample of 4117 teacher candidates in Spain. The instruments used for the data collection were adapted Spanish versions of the Perceived Stress Scale, the Maslach Burnout Inventory and the Connor-Davidson Resilience Scale. Finally, the conclusions drawn suggest that the preparation to obtain a permanent teaching post in Spain raises the levels of burnout syndrome and stress among teacher candidates.
Bioinformatics Analysis of Key Differentially Expressed Genes in Pericoronary Adipose Tissue Associated with the Diagnosis of Coronary Artery Disease
Authors: Li Yan , Guo Chao , Zhang Panpan , Hu Yahui , Adili Abasijiang , Xing Yan , Zhang Weimin 
Published: December 2022

Abstract
Objective: To investigate the potential key biomarkers for the diagnosis of coronary artery disease (CAD) in pericoronal adipose tissue using bioinformatics analysis, and to explore the mechanism underlying the occurrence and progression of CAD.
Methods: Two datasets were downloaded from the Gene Expression Omnibus (GEO) database for bioinformatics analysis, the differentially expressed genes (DEGs) were identified, and the relevant biological pathways of these genes were functionally annotated and enriched by the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses. Meanwhile, functional enrichment and protein–protein interaction (PPI) network analyses. Pericoronary adipose tissue and subcutaneous adipose tissue of patients with CAD(n=60) were analyzed and verified by quantitative reverse transcription polymerase chain reaction (RT-qPCR).
Results: A total of 82 DEGs from CAD patients and healthy individuals. The results of enrichment analysis showed that the top DEGs were mainly enriched in the retinol metabolism, carbon metabolism, and peroxisome proliferator-activated receptor (PPAR) signaling pathway. Among them, the PPAR signaling pathway with the strongest correlation with the key genes was associated with the downstream target protein Janus kinase (JAK), and verification using RT-qPCR revealed that the expression levels of JAK, monocyte chemoattractant protein-1 (MCP-1), platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31), IL-6, and leptin in pericoronary PVAT tissue were significantly upregulated. In contrast, the expression level of PPAR was significantly reduced (P<0.05).
Conclusion: This study revealed 4 DEGs in pericoronal adipose tissue for diagnosing CAD, which may improve understanding of CAD and assist scholars to explore the molecular mechanism of CAD.
Effect of Vertical Separation of Piers and Beams on Failure Modes of Bridge Piers
Authors: An Wenjun , Zhou Lin , Kang Meilan , Yang Hailin , Mo Lanyan 
Published: December 2022

Abstract
In this study, a double span continuous girder bridge is used to derive the dynamic response of the structure. By calculating the variation of vertical contact force of pier and beam, the vertical separation condition of pier and beam is put forward. By comparing the changes of the vertical contact force of pier and beam and the extreme value of longitudinal deformation of pier under the two conditions of separation or not, the influence of the dynamic response change caused by separation on pier failure is analyzed. According to the calculation, the separation of pier and beam is related to the excitation frequency and amplitude, and the separation will increase the risk of pier failure under compression, bending and shear. And the failure mode of bridge pier at the initial moment is separated. Therefore, it is of great significance to reasonably design bridges near faults and balances all kinds of possible pier damage.
NCAM1 Promotes the Proliferation and Migration of Pulmonary Arterial Smooth Muscle Cells via the ERK1/2 Pathway
Authors: Chen Yunwei , Yang Yunjing , Yang Lingzhi , Li Yan , Li Ailing , Huang Wei 
Published: December 2022

Abstract
Background: Pulmonary arterial hypertension (PAH) is a malignant vascular disease characterized by pulmonary arterial remodeling. Neural cell adhesion molecule 1 (NCAM1) is a cell surface glycoprotein that is involved in a variety of diseases, including cardiovascular disease. However, the relationship between NCAM1 and PAH is unknown.
Methods: Enzyme-linked immunosorbent assay, Bioinformatics methods, Echocardiography, Right heart catheterization, Hematoxylin-eosin staining, Immunofluorescent staining, Quantitative reverse transcription polymerase chain reaction, Western blotting, Cell Counting Kit-8, EdU staining, Scratch wound healing assay and Transwell migration assay were used to elucidate the role of NCAM1 in PAH.
Results: The protein expression levels of NCAM1 were increased in the plasma of PAH patients. Using bioinformatics methods, we found that the transcript levels of NCAM1 were also upregulated in the lung tissues of PAH patients. The expression levels of NCAM1 protein in the plasma of MCT-induced PAH rats were also increased. We found that both NCAM1 protein and mRNA expression levels were significantly enhanced in MCT rat lung tissues. Furthermore, we found that NCAM1 mRNA and protein levels were significantly upregulated in PDGF-BB-treated PASMCs. NCAM1 knockdown could partially reverse PDGF-BB-induced proliferation and migration of PASMCs. However, the effects were partially restored by tert-butylhydroquinone (TBHQ), an ERK1/2 activator. And recombinant rat NCAM1 protein promotes PASMC proliferation and migration and activates the ERK1/2 signaling pathway.
Conclusion: Our findings suggest that NCAM1 may be associated with pulmonary arterial hypertension and promotes the proliferation and migration of PASMCs via the ERK1/2 signaling pathway.
Co-exposure to cadmium and microplastics promotes liver fibrosis through the hemichannels -ATP-P2X7 pathway
Authors: Sun Jian , Qu Huayi , Ali Waseem , Chen Yan , Wang Tao , Ma Yonggang , Yuan Yan , Gu Jianhong , Bian Jianchun , Liu Zongping , Zou Hui 
Published: December 2022

Abstract
Background
The widespread use of plastic products and the imperfection of plastic recycling systems have led to a continuous increase in microplastics (PS) in the environment. Microplastics have an adsorption effect and can act as carriers for other pollutants in the environment. Cadmium (Cd) is a heavy metal that interacts with microplastics. However, the potential toxicity of co-exposure of cadmium and microplastics to the body is not clear. This study focuses on the effects of co-exposure to cadmium and microplastics on liver fibrosis and its mechanism.

Results

In this study investigated, Cd+PS exposure increased superoxide anion production and promoted extracellular ATP release compared with exposure to Cd or PS alone. Cd+PS increased inflammatory cell infiltration, activated the P2X7-NLRP3 signaling pathway, and promoted inflammatory factor release. Cd+PS aggravated Cd- or PS-induced liver fibrosis and induced liver inflammation. In AML12/HSC-T6 cell in vitropoisoning model, exposure of AML12 cells to Cd+PS increased the opening of connexin hemichannels and promoted extracellular ATP release. Treatment of HSC-T6 cells with the supernatant of AML12 cells exposed to Cd+PS significantly promoted HSC-T6 cell activation. Treatment of HSC-T6 cells with different concentrations of ATP produced similar results. TAT-Gap19TFA, an inhibitor of connexin hemichannels, significantly inhibited the ATP release and activation of Cd+PS-treated HSC-T6 cells. Finally, the expression of the ATP receptor P2X7 was silenced in HSC-T6 cells, which significantly inhibited their activation.

Conclusion

Cadmium and microplastics have a synergistic toxic effect on the liver, destroy the microenvironment in the liver, and promote the development of liver fibrosis through the hemichannel-ATP-P2X7 signaling pathway. Our study reveals the impact of co-exposure to cadmium and microplastics on chronic liver diseases, providing a theoretical basis for disease prevention and treatment.
Generalized Lipschitz and Besov spaces in terms of decay of Dunkl transforms in the space L2(Rd, wl(x)dx)
Authors: Ouadih Salah El , Daher Radouan 
Published: December 2022

Abstract
For functions f ∈ L2 (R d, wl (x)dx) with wl is a weight function invariant under the action of an associated Weyl group, we give necessary and sufficient conditions for f to belong to the generalized Lipschitz and Besov spaces in terms of the behaviour of their Fourier transformsˆftransformsˆ transformsˆf setting by means of kth-order moduli of continuity.