bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preclinical safety of a bionic tiger bone capsule in Sprague–Dawley rats and beagle dogs
Authors: Wan Shu‐Fang , Wang Quan‐Jun , Guan Yong‐Biao 
Published: August 2022

AbstractBackgroundJintiange capsule is composed of bionic tiger bone powder and has similar ingredients to natural tiger bone.ObjectiveTo characterize the subacute toxicities of Jintiange capsule in rats and beagle dogs for preclinical safety assessment.MethodsSuspensions of Jintiange capsule were given via gastric lavage over a 26‐week period at low (500 mg/kg), mid (1500 mg/kg) and high doses (4000 mg/kg) in SD rats. Beagles were given by gastric lavage of suspensions of Jintiange capsule once daily for 6 days per week for 39 weeks at low (300 mg/kg), mid (900 mg/kg) or high dose (2000 mg/kg).ResultsRepeated gastric lavages of suspensions of Jintiange capsule at doses from 500 to 4000 mg/kg over 26 weeks caused no significant toxicity (No Observed Adverse Effect Level, NOAEL) in rats. In addition, repeated gastric lavages of suspensions of Jintiange capsule at doses from 300 to 2000 mg/kg over 39 weeks caused NOAEL in beagles.ConclusionsJintiange capsule was safe in rats at a dose 66.7 times the clinically recommended dose and in beagles at 33.3 times the clinically recommended dose. Our subacute toxicity studies in rats and beagles demonstrated no apparent overall toxicities including haematotoxicities, hepatotoxicities and renal toxicities.
Surgical treatment for left atrial rupture due to myxomatous mitral valve disease in three dogs: A case report
Authors: Yoshida Tomohiko , Matsuura Katsuhiro , Chieh‐Jen Cheng , Aboshi Yuki , Yamada Shusaku , Yotsuida Hideki , Hasegawa Mizuki , Hendawy Hanan A. , El‐Husseiny Hussein M. , Takahashi Yusuke , Oonuma Yuki , Yaginuma Youta , Fukuzumi Shou , Tanaka Ryou 
Published: August 2022

AbstractIntroductionMyxomatous mitral valve degeneration (MMVD) is an acquired heart disease which sometimes result in pulmonary oedema and left atrial rupture. In previous reports, left atrial rupture has been non‐surgically controlled and its prognosis investigated. There is, however, no report concerning surgically treated left atrial rupture with mitral valvuloplasty and follow‐up results.ObjectivesThis report aimed to develop a surgical strategy for a case of left atrial rupture caused by MMVD.Materials and methodsThree dogs were presented at a private hospital for surgical treatment of MMVD. All three dogs had a previous history of left atrial rupture due to MMVD. The left atrium rapture was diagnosed from indicating that characteristics of the drained pericardial effusion consistent with blood. Mitral valvuloplasty was performed in all dogs using an extracorporeal circulation machine, and the surgical procedure was modified according to each case. In cases with severe adhesion between the pericardial and left atrial appendage, suturing of the left atrial appendage was performed strategically. Additionally, in cases with severe hypotension caused by left atrial rupture, cardiopulmonary bypass was started as soon as possible during the surgical procedure.Discussion and ConclusionSince the haemodynamics of all dogs had improved, and the owner reported no cardiac‐related clinical signs, all drugs were withdrawn 3 months after surgery. Since left atrial rupture due to MMVD can cause hypotension, cardiopulmonary bypass should be started as soon as possible during the surgical procedure to maintain the blood pressure and suturing of the left atrial appendage should be performed strategically.
Four cases of stomach perforation in adult horses
Authors: Dahmen Katrin , Fischer Holger , Burczynski Victoria , Albanese Valeria , Muñoz Encarnación 
Published: August 2022

AbstractFour horses were diagnosed with full‐thickness perforation of the stomach wall. Three of them developed a mature abscess associated with the perforation and one of them developed massive adhesions in the area. The clinical and laboratory findings and diagnostic procedures are described together with a discussion about potential pathogenesis for these rare pathologies in horses.
Religionslose Personen in der Schweiz
Authors: Tanner Pascal 
Published: August 2022

ZusammenfassungImmer mehr Menschen in der Schweiz sagen von sich selbst, dass sie keiner Konfession oder Religion angehören. Aktuell bilden sie zusammen mit reformiert zugehörigen und katholisch zugehörigen Personen eine der drei größten Gruppen – je nach Datensatz und Erhebungsmethode seit Kurzem sogar die größte von allen. In diesem Beitrag stehen religionslose Personen und damit das Phänomen derindividuellen Religionslosigkeitim Mittelpunkt. Vertieft untersucht werden die beiden folgenden Aspekte: Einerseits schlägt der Beitrag eine Brücke zum allgemeinen Forschungsdiskurs über Religionslosigkeit. Er fragt danach, wie sich in der Schweiz wohnhafte religionslose Personen aktuell beschreiben lassen in Bezug auf Soziodemografie, Spiritualität, Religiosität und Sozialisation. Dabei wird deutlich, was sich bereits an anderer Stelle zeigte: Religionslose sind vergleichsweise jung und überdurchschnittlich gut gebildet. Ebenfalls tritt dabei ein Phänomen in Erscheinung, das bislang erst ansatzweise untersucht wurde: Religionslose weisen überproportional häufig einen Migrationshintergrund auf. Andererseits vertieft dieser Beitrag den für die Säkularisierungsforschung zentralen Aspekt der Sozialisation. Er stellt ein Modell vor, das Aufschluss über typische Sozialisationserfahrungen religionsloser Personen gibt. Als wichtigstes Resultat aus der Modellbildung geht hervor, dass Religionslosigkeit typischerweise dort ihren Anfang nimmt, wo auch Sozialisation beginnt: Bei den Eltern der befragten Personen und deren Verhältnis zum Religiösen. Alle ausgeführten Analysen basieren auf den Daten der MOSAiCH-Befragung von 2018 und wurden mit den Werkzeugen der quantitativen Sozialforschung erarbeitet.
Politik und Religion in der Schweiz
Authors: Liedhegener Antonius 
Published: August 2022

ZusammenfassungPolitik und Religion in der Moderne – das ist das Wechselverhältnis zweier komplexer Größen. Der vorliegende Beitrag macht ausgehend vom Forschungstand für die Schweiz dieses Wechselverhältnis anhand von aktuellen Befragungsdaten in seiner Komplexität in der Bevölkerung und Wählerschaft sichtbar. Es wird die Annahme überprüft, dass Religion trotz der nachhaltigen Säkularisierung und Entkirchlichung nach wie vor einen Einfluss auf die Schweizer Politik hat. Politik wird unter den Aspekten von Macht und Einfluss (politics), politischen Sachthemen (policy) und politischer Gemeinschaft (polity) analysiert. Gefragt wird nach dem Einfluss von Religion auf Wahlteilnahme, parteipolitische Präferenzen, politische Einstellungen und Sachthemen sowie auf die Bewertung des politischen Systems. Anhand von Umfragedaten der MOSAiCH-Erhebung 2018, die den ISSP 2018 zum Thema Religion enthält, wird Religion als ein beim Einzelnen potenziell mehrschichtiges Phänomen bestimmt und operationalisiert. Mit einer seriellen Kontingenztabellenanalyse werden verschiedene, aus den Theorien der Wahlforschung abgeleitete Wirkungsannahmen bzw. -mechanismen statistisch überprüft. Religion wird definiert als Mitgliedschaft in gesellschaftlichen Großgruppen, Gelegenheitsstruktur für Face-to-face-Kontakte, Teil persönlicher Überzeugungen und Einstellungen sowie eigenständige soziale Identität. Wie die empirische Analyse zeigt, tragen alle diese Aspekte von Religion zur Erklärung der ermittelten, zum Teil recht starken Zusammenhänge bei. Schlussendlich kann aber keine der theoretischen Annahmen allein überzeugen, denn de facto korrelieren fast alle religionsbezogenen Indikatorvariablen so stark miteinander, dass sich die statistischen Erklärungsleistungen ähneln. Insgesamt zeigt sich: Ein christliches Profil der Wählenden stärkt in der Schweiz die politische Mitte allgemein. Es sind heute aber weniger die alten konfessionellen Gräben als vielmehr neue politische Konflikte um religionsbezogene Themen und soziale Identitäten, die dem Faktor Religion seine zum Teil konfliktive Wirkung in der Schweizer Politik verleihen. Dort, wo Religion und Religionspolitik strittig und konfliktbeladen sind, speist sich der Konflikt zudem stärker aus der Politik selbst als aus dem religiösen Feld. Diese Einsichten dürften Konsequenzen sowohl für eine angemessene gesellschaftliche Problembearbeitung der Streitfragen als auch für die Revision des verbreiteten, aber falschen Bildes der Religionsgemeinschaften als Konfliktursache haben. Im europäischen Vergleich weisen die Mitglieder der verschiedenen Religionsgemeinschaften in der Schweiz nämlich ein wohl weitestgehend harmonisches Neben- und Miteinander auf – eine durchaus nicht selbstverständliche Tatsache, deren genauer Prüfung nach Art, Umfang und Ursachen die quantitative Sozial- und Religionsforschung zukünftig einen Teil ihrer Aufmerksamkeit widmen sollte.
Ausblick
Authors: Stolz Jörg , Bünker Arnd , Liedhegener Antonius , Baumann-Neuhaus Eva , Becci Irene , Dandarova Robert Zhargalma , Senn Jeremy , Tanner Pascal , Wäckerlig Oliver , Winter-Pfändler Urs 
Published: August 2022

ZusammenfassungDieses Buch versammelt Beiträge zur Beschreibung von Trends in der Religionslandschaft der Schweiz. Die vergleichende Betrachtung der Texte zeigt, dass sich die in den früheren Studien beschriebenen Trends in den letzten zehn Jahren weitgehend fortgeschrieben haben. Es ist zu einer weiteren Säkularisierung und religiösen Individualisierung gekommen. Die religiöse Praxis, der religiöse Glaube, die religiöse Zugehörigkeit, wie auch die Kirchenbindung haben weiter abgenommen, während die Rede von einer persönlichen Spiritualität zunimmt. Insofern zeigt unser Buch zunächst viel Bekanntes. Im Vergleich zu den früheren Studien zur Religionslandschaft der Schweiz sind jedoch auch neue Gesichtspunkte und Einsichten entstanden.
Having Fun
Authors: Chevez Agustin 
Published: August 2022

AbstractAlong one of the most popular pilgrimages in the world, El Camino de Santiago, in Spain, walkers are greeted with “buen Camino” to wish them a good way both physically and spiritually. My version of buen Camino was an enthusiastic and quintessentially Australian “Have fun!” followed by a wave. I would then wave back with a cheerful “thanks, I will!”
Life at 4.6 km/h
Authors: Chevez Agustin 
Published: August 2022

AbstractBefore setting out on the walk, I had read books about pilgrimages and the practicalities of long-distance trekking. I got inspiration from the former and good tips from the latter. Hot tip: if your hair stands on end, you should drop on your knees and bend forward, but not lie flat on the floor, because lightning is about to strike you.
My Backpack
Authors: Chevez Agustin 
Published: August 2022

AbstractMy backpack was very sturdy and if I interpreted what Ballistic Nylon Fabric meant correctly, it was bullet proof too. I carried two packs: a big one with a 70 litre capacity and a small 15 litre one which I wore in front to balance the weight of the larger pack on my back. I’d originally purchased the packs for an overseas trek that required something sturdy to endure rocky terrain and the better-not-to-know things that happen when one checks in their luggage on an international flight.
Where Are the Idiots?
Authors: Chevez Agustin 
Published: August 2022

AbstractThe warnings about the idiots concerned me. ‘The idiots’ were presumably so not because of their dim intelligence, but because they were out there to cause trouble. Most concerning of all, was the way in which the people voicing these warnings looked at me. They tilted their head ever so slightly, distorted their mouth as if tasting a lemon, and squinted their eyes – I didn’t stand a chance against the idiots.
About This book
Authors: Chevez Agustin 
Published: August 2022

AbstractThis is a specific type of book, it is a guidebook; and a guidebook serves two purposes. First, it helps you get somewhere you want to go. Second, it makes you aware of historic events, art, architecture, cuisine, culture, and people of the places you go through. It is unlikely you would find construction details of a building, or the recipe for the dishes you enjoy during your travels in a guidebook. Instead, it succinctly describes how all these elements have come together and combined themselves in the experience of a place.
The Perfect Day
Authors: Chevez Agustin 
Published: August 2022

AbstractDay 30 was a short 13 km walk from Mollymook Beach to Conjola in NSW. It was one of the shortest walks of the whole pilgrimage and I covered it in less than 3 hours. Weatherwise, I wished I had spent more time on the road on that sunny day which was pleasantly cool and completely devoid of my nemesis wind.
Spoiler Alert
Authors: Chevez Agustin 
Published: August 2022

AbstractNot long after I returned from my pilgrimage, I was approached by a publisher requesting an article about isolation in the workplace [3]. It was in response to tragic events that transpired at the remote Bellingshausen Station in Antarctica. The incident involved a researcher allegedly stabbing a colleague for giving away the endings of the books he was reading [4]. One spoiler too many led to the unfortunate stabbing.
All Roads Lead to Rome
Authors: Chevez Agustin 
Published: August 2022

AbstractFollowing Signposts takes us through trails that expose us to unique ways of viewing work, the workplace, and ourselves. However, the process can be overwhelming. Yet, if these markers are to deliver on their promise, they would have to converge in a single destination: a better place to work, Fig. 36.1. Consequently, it is not necessary to follow them all.
The Herzog Enigma
Authors: Chevez Agustin 
Published: August 2022

AbstractThe renowned German filmmaker Werner Herzog started walking from Munich to Paris in a bitterly cold northern European winter, believing that in doing so he could save his friend and film critic Lotte Eisner. I will not distort what Herzog wrote about so beautifully in his book Of Walking in Ice [22] but, for me, the most striking part of his journey remains its spontaneity. True, he had a strong motivation.
Patient satisfaction with divided anesthesia care
Authors: Koster Kira-Lee , Björklund Carolin , Fenner Sebastian , Flierler Wolfgang Johann , Laupheimer Michael , Burri Katharina , Nübling Matthias , Heidegger Thomas 
Published: August 2022

Abstract
Background
Up to now, no prospective cohort study using a validated questionnaire has assessed patients’ expectation and perception of divided anesthesia care and its influence on patient satisfaction.

Objective
We assessed patient satisfaction with divided anesthesia care in a district general hospital in Switzerland. We hypothesized that patient expectations, combined with their perceptions of the (un)importance of continuous anesthesia care would influence patient satisfaction.

Material and methods
A total of 484 eligible in-patients receiving anesthesia from October 2019 to February 2020 were included and received preoperative information about divided care via a brochure and face-to-face. The primary outcome was the assessment of patient satisfaction with divided anesthesia care using a validated questionnaire. In group 1 continuity of care was considered important but not performed. In group 2 continuity was ensured. In group 3 continuity was regarded as not important and was not performed. In group 4 patients could not remember or did not answer. A psychometrically developed validated questionnaire was sent to patients at home after discharge.

Results
A total of 484 completed questionnaires (response rate 81%) were analyzed. In group 1 (n = 110) the mean total dissatisfaction score was 25% (95% confidence interval [CI] 21.8–28.1), in group 2 (n = 61) 6.8% (95% CI 4.8–8.7), in group 3 (n = 223) 12.1% (95% CI 10.7–13.4), and in group 4 (n = 90) 15% (95% CI 11–18); ANOVA: p < 0.001, η = 0.43. Of the patients 286 (59%) considered continuity of care by the same anesthetist relatively unimportant (34%) or not important at all (25%). The other 40% considered it important (22%) or very important (18%).

Conclusion
Despite receiving comprehensive preoperative information about divided anesthesia care, 40% of patients still considered continuity of care by the same anesthetist important. We recommend further research evaluating whether and how patient expectations can be modified towards the common practice of divided care and patient satisfaction can be increased.
Association between prehospital FPS and ROSC in adults with OHCA
Authors: Montag Sarah , Herdtle Steffen , John Samuel , Lehmann Thomas , Behringer Wilhelm , Hohenstein Christian 
Published: August 2022

Abstract
Background
Advanced airway management (AAM) is part of the standard treatment during advanced cardiac life support (ACLS). Current studies underline the importance of a first-pass intubation success (FPS) during in-hospital ACLS. It was shown that a failed initial intubation attempt in out-of-hospital cardiac arrest (OHCA) patients in the emergency department is an independent risk factor for the decreased effectiveness of ACLS measured by the return of spontaneous circulation (ROSC).

Objective
This study first examines the association between prehospital FPS and ROSC in adults with OHCA and second identifies factors associated with FPS and ROSC. The initial hypothesis was that FPS would increase the probability of ROSC as well as decrease the time to ROSC.

Material and methods
A retrospective multicenter analysis of 180 adult non-traumatic OHCA patients on whom advanced airway management (AAM) was performed between July 2017 and December 2018 in five different German physician-staffed ambulance stations. For information on FPS the Intubation Registry, and for information on ROSC the German Resuscitation Registry were used. In addition to yes/no questions, multiple answers and free text answers are possible in those questionnaires. The main outcome variables were ‘FPS’, ‘ROSC’ and ‘time to ROSC’. Mann-Whitney tests, χ2-tests, Fisher’s exact tests and multivariate binary logistic regressions were used for the statistical evaluation. Demographic factors, characteristics of the performer, selected equipment, laryngoscopy type, intubation method, medications, verification of tube position, respiratory evaluation, complications and time to ROSC were examined with respect to the influence on FPS. Concerning ROSC, the following factors were examined: demographic factors, initial heart rhythm, initial breathing, medications, defibrillation and AAM.

Results
An FPS was recorded in 150 patients (83.3%), and ROSC was achieved in 82 patients (45.5%) after an average time of 22.16 min. There was a positive association between FPS and ROSC (p = 0.027). In patients with FPS, a trend for shorter time to ROSC was observed (p = 0.059; FPS 18 min; no FPS 28 min). The use of capnography (odds ratio, OR = 7.384, 95% confidence interval, CI 1.886–28.917) and complications during AAM (OR = 0.033, 95% CI: 0.007–0.153) were independently associated with FPS. The independent factor associated with ROSC was FPS (OR = 5.281, 95% CI: 1.800–15.494).

Conclusion
In prehospitally resuscitated adult OHCA patients with AAM, FPS is associated with a higher chance of ROSC.
Stable generalized finite element method (SGFEM) for three-dimensional crack problems
Authors: Cui Cu , Zhang Qinghui , Banerjee Uday , Babuška Ivo 
Published: August 2022

AbstractThis paper proposes a stable generalized finite element method (SGFEM) for the linear 3D elasticity problem with cracked domains. Conventional material-independent branch functions serve as singular enrichments. We prove that the proposed SGFEM with the geometric enrichment scheme yields the optimal order of convergence in the energy norm, O(h), for fully 3D elasticity planar crack problems; h is the mesh parameter. To improve the conditioning of SGFEM, two stability techniques have been employed, namely, (a) a cubic polynomial has been used as the PU (partition of unity), instead of the standard FE hat-functions, to address the possible almost linear dependence between the PU functions and the enrichments, and (b) a local principal component analysis (LPCA) has been implemented to address the local bad conditioning produced by multi-fold enrichments at a node. The scaled condition number for the proposed SGFEM is shown to be $$O(h^{-2})$$

O
(

h

-
2

)

(same as that of a standard Finite Element Method), for various relative positions of crack surface and mesh. The robustness of the scaled condition number for the proposed SGFEM, with respect to the relative positions of the crack-surface and the element boundaries, has been observed numerically. The numerical experiments for both the planar and fully 3D planar crack problems are presented to show the efficiency of the proposed SGFEM.
A review of the scientific knowledge of the seascape off Dronning Maud Land, Antarctica
Authors: Lowther Andrew , von Quillfeldt Cecilie , Assmy Philipp , De Steur Laura , Descamps Sebastien , Divine Dmitry , Elvevold Synnøve , Forwick Matthias , Fransson Agneta , Fraser Alexander , Gerland Sebastian , Granskog Mats , Hallanger Ingeborg , Hattermann Tore , Itkin Mikhail , Hop Haakon , Husum Katrine , Kovacs Kit , Lydersen Christian , Matsuoka Kenichi , Miettinen Arto , Moholdt Geir , Moreau Sebastien , Myhre Per Inge , Orme Lisa , Pavlova Olga , Tandberg Ann Helene 
Published: August 2022

AbstractDespite the exclusion of the Southern Ocean from assessments of progress towards achieving the Convention on Biological Diversity (CBD) Strategic Plan, the Commission for the Conservation of Antarctic Marine Living Resources (CCAMLR) has taken on the mantle of progressing efforts to achieve it. Within the CBD, Aichi Target 11 represents an agreed commitment to protect 10% of the global coastal and marine environment. Adopting an ethos of presenting the best available scientific evidence to support policy makers, CCAMLR has progressed this by designating two Marine Protected Areas in the Southern Ocean, with three others under consideration. The region of Antarctica known as Dronning Maud Land (DML; 20°W to 40°E) and the Atlantic sector of the Southern Ocean that abuts it conveniently spans one region under consideration for spatial protection. To facilitate both an open and transparent process to provide the vest available scientific evidence for policy makers to formulate management options, we review the body of physical, geochemical and biological knowledge of the marine environment of this region. The level of scientific knowledge throughout the seascape abutting DML is polarized, with a clear lack of data in its eastern part which is presumably related to differing levels of research effort dedicated by national Antarctic programmes in the region. The lack of basic data on fundamental aspects of the physical, geological and biological nature of eastern DML make predictions of future trends difficult to impossible, with implications for the provision of management advice including spatial management. Finally, by highlighting key knowledge gaps across the scientific disciplines our review also serves to provide guidance to future research across this important region.