bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pulmonary Brucellosis in Xinjiang, China: A Retrospective Study of 38 Cases and Review of the Literature
Authors: Lan Siqin , Chen Dawei , He Yuanlin , Liu Wenya , Guo Hui 
Published: February 2022

Abstract
Background: Pulmonary brucellosis (PB) is a unique infection caused by Brucella and it is challenging to diagnose PB accurately for its diverse clinical manifestations. We tried to summarize PB’s features to enhance our awareness of it and offer differential diagnoses in endemic zones by evaluating their demographic characteristics, clinic data, and imaging findings.Methods: The demographic characteristics, clinic data and the imaging findings of 38 patients with PB from January 2011 to January 2020 in Xinjiang Medical University Affiliated First Hospital were presented. Results: The median age were 51 years. The most common clinical manifestations were fever (73.7%). The laboratory data decreased significantly, containing hematocrit (84.2%), hemoglobin (78.9%), red blood cell count (65.8%), eosinophilic count (47.3%). On computed tomography (CT), 27 patients had nodules, 23 (60.5%) interstitial infiltration, 16 (42.1%) consolidation, 15 (39.5%) patchy shadow, and 7 (18.4%) atelectasis. 11 patients had pleural thickening and 10 (26.3%) patients suffered from hydrothorax. 20 (52.6%) patients had lymphadenectasis in the hilum of lung or mediastinum, three pericardial effusion, and 1 pericardial thickening. Conclusion: PB should not be excluded when a patient has chest radiologic abnormalities, meanwhile complain of an atypical high fever and fatigue, especially in the epidemic region.
Inequities in Healthcare Seeking Among Migrants and Residents of Climate Affected Coastal Area of Bangladesh
Authors: Khanam Mosammat Ivylata , Khalek Abdul , Hanifi Syed Manzoor Ahmed , Rasheed Sabrina 
Published: February 2022

Abstract
Background:Climate change induced sea level rise, increased soil salinity and poor socio-economic condition have triggered migration around the world. So far, the impact of migration on health and healthcare utilization have not been studied adequately especially in Bangladesh. Our study examines impact of migration on healthcare seeking behavior of people living in low-lying coastal areas of Bangladesh. Methods:We analyzed data from Chakaria, Health and Demographic Surveillance System, 2017-18. Univariate analysis and regression analysis were conducted to assess the determinants of migration. Finally, we assessed differences in health care seeking behavior between migrants in low-lying coastal areas and plain areas. Stata version 14 was used for analysis. Results:In terms of determinants of migration, adults, males, educated, unemployed and poor were significantly more like to migrate compared to children, females, people with little education, those engaged in agriculture or other occupations and wealthier households. For pregnancy related services healthcare utilization was significantly lower in coastal areas compared to the plains. In terms of utilization of maternal and child health services, service use was 2-28 % lower among residents of low-lying coastal regions and 13-70% lower among coastal migrants compared to those living in plains. Conclusion:Our findings suggest that in terms of maternal health services there was geographic inequity in service utilization favoring the residents of plains and being a migrant significantly increases the geographical disadvantage in terms of maternal health services. The existing inequity indicates the necessity of immediate action to address the health and healthcare utilization of residents of coastal area with special attention to the migrants in Bangladesh.
Dynamic analysis of bottom hole pressure of a fractured horizontal well in fractal flow medium
Authors: liu hailong 
Published: February 2022

Abstract
This paper addresses the problem of the bottom hole pressure (BHP) behavior of a fractured horizontal well in a fractal flow medium. A detailed step by step procedure for obtaining the semi-analytical solution is present. The proposed method is validated available by comparing previous analytical solution. Sensitivity analyses about the influential parameters including wellbore storage factor, fracture properties, skin coefficient, permeability modulus and horizontal wellbore length on BHP are investigated in detail. The fracture scale (fracture half-length, fracture width and fracture number) mainly affects the channeling flow from the non-fracture zone to the fracture zone. With the increase of the fracture scale, the intensity of the channeling flow decreases and its duration becomes shorter. The fracture fractal index does not affect channeling flow its appearing time and intensity, but its influence on typical curves is mainly reflected in the seepage stage of the fracture zone. The pressure and derivative curves gradually upward warp with the increase of time, and the upward warping amplitude increases with the increase of the fractal index. The advantage of this method is to incorporate well geometry (well storage factor) and reservoir structure (the fractal index). The findings of this study can help for better understanding of well test interpretation of fractal reservoir
Intraspecific and Interspecific Comparison of Toxicity of Ladybirds (Coleoptera: Coccinellidae) With Contrasting Colouration
Authors: Aslam Muhammad , Nedvěd Oldřich 
Published: February 2022

Abstract
Ladybirds (Coccinellidae) use toxic compounds, mostly alkaloids in their haemolymph, for defence against predators and other enemies. The toxicity of ladybirds to predators cannot be directly assessed because predators show avoidance reactions without ingesting the beetles. The alkaloid of ladybird Harmonia axyridis showed wide range toxicity to diverse non-target organisms. Thus, we used a quick, inexpensive and easy-to-perform method using bioassays on water flea Daphnia magna for comparative quantification of the toxicity (LD50) of whole body extracts from several species of ladybirds that differ in their warning colouration. Alien invasive aposematic polymorphic ladybird H. axyridis was more toxic than all the other species examined: aposematic Adalia bipunctata > cryptic Cynegetis impunctata > aposematic Coccinella septempunctata > slightly aposematic Calvia quatuordecimguttata. Three months old adults of H. axyridis were 3.8 times more toxic than two weeks and one month old adults. The two most common colour morphs (non-melanic novemdecimsignata and melanic spectabilis) did not differ in their toxicity.
Mechanochemical Ionization – Differentiating Pressure-, Shear-, and Temperature-Induced Reactions in a Model Phosphate
Authors: Muser Martin H. , Sukhomlinov Sergey V. , Kickelbick Guido 
Published: February 2022

Abstract
Using density-functional theory based molecular dynamics simulations, we study stress and temperature-induced chemical reactions in bulk systems containing triphosphoric acid and zinc-phosphate molecules. The nature of the reactants depends sensitively on the imposed conditions, e.g., isotropic and even more so shear stress create ionic reactants. Instead, zwitterions and water molecules emerge from thermal cycles. Hydrostatic stresses required for reactions to occur lie well below those typical for tribological micro-contacts and are further reduced by shear. During the moment of impact, many protons are mobile, even if they bond to groups that formally remain inert in a compression/decompression cycle. Our findings are consistent with a variety of observations on the triboelectric charging of insulators but contradictory to the hot-spot model.
Comparison of Deep Vein Thrombosis Risks in Acute Respiratory Distress Syndrome Caused by COVID-19 and Bacterial Pneumonia: A Retrospective Cohort Study
Authors: Cui Na , Jiang Chunguo , Yang Chenlu , Zhang Liming , Feng Xiaokai 
Published: February 2022

Abstract
Background: High incidence of deep vein thrombosis (DVT) has been observed in patients with acute respiratory distress syndrome (ARDS) caused by COVID-19 and those by bacterial pneumonia. However, it is also important to differentiate between these two groups of patients. Study Design and Methods: We performed a retrospective cohort study to investigate the difference of DVT between the two independent cohorts of ARDS and eventually enrolled 240 patients, 105 of whom with ARDS caused by COVID-19 and 135 by bacterial pneumonia. We analyzed demographics and clinical characteristics for patients with and without DVT in these two cohorts and explored the main differences and similarities between them. Results: The 28-days incidence of DVT in COVID-19 cohort was higher than that in bacterial pneumonia cohort (57.1% vs 41.5%, P=0.016). Taking death as competitive risk, Fine-Gray test showed no significant difference in 28-day cumulative incidence of DVT between these two groups (P=0.220). Fine-Gray competing risk analysis showed an association between CK (creatine kinase isoenzyme)-MB levels, PaO2 (partial pressure of arterial oxygen)/FiO2 (fraction of inspired oxygen) ratios, D-dimer levels and DVT in COVID-19 cohort and an association between serum creatinine levels, IMV, and DVT in bacterial pneumonia cohort. The sensitivity and specificity of corresponding receiver operating characteristic curve originating from the combination of CK-MB levels, PaO2/FiO2 ratios and D-dimer levels ≥ 0.5 µg/mL was not inferior to those of the Padua prediction score and the Wells score for screening for DVT in COVID-19 cohort. Conclusions: Compared with patients with ARDS caused by bacterial pneumonia, the incidence of DVT is higher by logistic model in patients with ARDS caused by COVID-19, and the risk factors for DVT are completely different. Our novel prediction model can aid early identifying patients with high risk for DVT. Keywords: Acute Respiratory Distress Syndrome; Pneumonia, Bacterial; COVID-19; Deep Vein Thrombosis
Early predictive factors for postoperative pancreatic fistula after distal pancreatectomy for pancreatic cancer: A retrospective study
Authors: Fukada Masahiro , Murase Katsutoshi , Higashi Toshiya , Yokoi Ryoma , Tanaka Yoshihiro , Okumura Naoki , Matsuhashi Nobuhisa , Takahashi Takao , Yoshida Kazuhiro 
Published: February 2022

Abstract
Background: Postoperative pancreatic fistula (POPF) is the most serious complication of distal pancreatectomy (DP). When POPF occurs and becomes severe, it causes secondary complications and leads to a longer treatment period. Therefore, especially for pancreatic cancer (PC), POPF may have a negative impact on not only short-term outcomes, but also on postoperative treatment. This study aimed to identify early predictive factors of POPF after DP for PC.Methods: This retrospective, single-institution study comprised of 55 patients with PC who underwent DP (excluding simultaneous resection of other organs and other pancreatic diseases) between January 2010 and December 2021 at the Gifu University Hospital. We statistically analyzed pre-, intra-, and post-operative 23 factors to identify early predictive factors for POPF. Results: According to the definition and grading of the International Study Group of Pancreatic Fistula (ISGPF), 12 (21.8%) of 55 patients had POPF grades B and C. In the univariate analysis, POPF was significantly associated with the pancreas-to-muscle signal intensity ratio on T1-weighted magnetic resonance imaging (SIR on T1-w MRI), the drainage fluid amylase (D-Amy) level on postoperative day 3 (POD3), C-reactive protein (CRP) on POD3, and heart rate on POD3. In multivariate analysis, pancreas-to-muscle SIR on T1-w MRI (>1.37; odds ratio [OR] 17.08; 95% confidence interval [CI] 1.64 – 598.16; p = 0.02), D-Amy level on POD3 (>1200 U/L; OR 20.00; 95% CI 1.73 – 563.83; p = 0.02) and heart rate on POD3 (>100 bpm; OR 15.33; 95% CI 1.53 – 258.45; p = 0.02) were identified as independent early predictive factors for POPF. Conclusion: Preoperative pancreas-to-muscle SIR on T1-w MRI and postoperative D-Amy level and heart rate significantly correlated with POPF after DP for PC. Postoperative management based on these predictive factors may contribute to shortened hospital stay and smooth introduction to postoperative treatment.
Short-Term Effects of a Supervised Exercise Program in Addition to Electrical Stimulation or Kinesio Taping on Pain and Disability in Patients with Chronic Low Back Pain: A Randomized Controlled Trial
Authors: Aguilar-Ferrándiz María Encarnación , Matarán-Peñarrocha Guillermo A. , Tapia-Haro Rosa María , Castellote-Caballero Yolanda , Martí-García Celia , Castro-Sánchez Adelaida María 
Published: February 2022

Abstract
Background: Chronic low back pain it is one of the most common health problems worldwide. Usually is accompanied by a complex set of symptoms and generates significant direct and indirect socioeconomic and health costs. From a therapeutic point of view, there are a wide variety of methods to address the treatment of this pathology, however, these therapies have not been shown definitive efficacy.To investigate the effect of a mixed treatment with exercise and electrical stimulation versus exercise and kinesio taping in patients with non-specific chronic low back pain. Methods: A total of 58 patients participated in this single-blinded randomised clinical trial. Participants were assigned to the exercises- kinesio taping group, or exercises- analgesic current group, both received 12 treatment sessions. Disability, fear of movement, anxiety, depression, sleeps quality, pain, lower limb mechanosensitivity and pressure-pain thresholds were recorded at baseline and after 4 weeks of treatment.Results: The 2x2 mixed analysis of covariance test showed statistically significant differences between groups for pain (P=0.046). Pair-wise comparisons with baseline demonstrated significant differences for both groups in pain (P ≤ 0.001), disability (P ≤ 0.001), pressure-pain thresholds (P ≤ 0.044), lower limb mechanosensitivity, (P ≤ 0.047), anxiety (P ≤ 0.001), depression (P ≤ 0.001) and sleep quality (P ≤ 0.010). Conclusions: Patients with chronic low back pain who received a combined treatment of exercises and kinesio taping or analgesic current showed an improvement in pain, disability, anxiety, depression and sleep pattern. Moreover, exercises combined with electrotherapy produces greater improvements over these variables.Trial registration number: NCT02812459
Changes in a Sensorimotor Network, Occipital Network, and Psychomotor Speed With in Three Months After Focal Surgical Injury in Pediatric Patients with Benign Intracranial Space-occupying Lesions
Authors: Guan Xue-Yi , Zheng Wen-Jian , Fan Kai-Yu , Han Xu , Li Xiang , Yan Zi-Han , Lu Zheng , Gong Jian 
Published: February 2022

Abstract
Background

Studies on cognition and brain networks after various forms of brain injury mainly involve traumatic brain injury, neurological disease, tumours, and mental disease. There are few related studies on surgical injury and even fewer pediatric studies. This study aimed to preliminarily explore the cognitive and brain network changes in children with focal, unilateral, well-bounded intracranial space-occupying lesions (ISOLs) in the short term period after surgery.
Methods

We enrolled 15 patients (6–14 years old) with benign ISOLs admitted to the Department of Pediatric Neurosurgery of the Beijing Tiantan Hospital between July 2020 and August 2021. Cognitive assessment and resting-state functional magnetic resonance imaging (rs-fMRI) were performed. Regional homogeneity (Reho), seed-based analysis (SBA) and graph theory analysis (GTA) were performed. Paired-T test were used for statistical analysis of cognitive assessment and rs-fMRI. Gaussian random-field theory correction (voxel p-value <0.001, cluster p-value <0.05) was used for Reho and SBA. False discovery rate correction (corrected p value<0.05) for GTA.
Results

Our results showed that psychomotor speed decreased within three months after surgery. Further, rs-fMRI data analysis suggested that sensorimotor and occipital network activation decreased with low information transmission efficiency.
Conclusion

We prudently concluded that the changes in cognitive function and brain network within three months after surgery may be similar to ageing and that the brain is vulnerable during this period.
Proportion And Factors Associated With Intra-Procedural Pain Among Women Undergoing Manual Vacuum Aspiration For Incomplete Abortion At Mbarara Regional Referral Hospital, Uganda
Authors: Opee Jimmyy , Mayanja Stephen Bawakanya , Bongomin Felix , Orach Christopher Garimoi , Ngonzi Joseph 
Published: February 2022

Abstract
Background: Intra-procedural pain (IPP) is common among women undergoing Manual Vacuum Aspiration (MVA) for incomplete abortion. Globally, the proportion varies between 60% to 90% while in Sub-Saharan Africa including Uganda, the proportion varies between 80% to 98%. IPP management during MVA include Para-cervical block (using 1% lidocaine) or an opioid (using 100mg of intravenous pethidine). Objectives: This study determined the proportion and factors associated with IPP among women undergoing MVA for incomplete abortion at MRRH.Methods: We conducted a cross sectional study among 207 women who underwent MVA for incomplete abortion from 17th December 2020 to 28th May 2021. An interviewer-administered structured questionnaire was used, and pain assessment was done using VAS considering an IPP as a pain score of 6 or more. The participant characteristics were summarized. The proportion of women with IPP was calculated. We performed multivariable logistic regression to determine the factors associated with IPP. Results: We consecutively enrolled 207 women with a mean age of 25.8 ±5.8 years. The proportion of women with IPP undergoing MVA at MRRH was 82.6% (95% C.I: 76.8 — 87.2). The factors significantly associated with IPP were age and cervical dilatation. The odds of IPP increased with decreasing age of the women; compared to older women (aged >30 years), teenagers (age<20 years); OR=8 (95% CI=1.85-34.61) (p=0.005), while women aged 20-24 years; OR=3.45 (95% CI=1.47-8.20) (p=0.004), and those aged 25-30 years; OR=2.84 (95% CI=1.20-6.74) (p=0.018). Women with cervical dilatation of 1-2 cm had the odds of IPP increased; OR=2.27 (95% CI=1.11-4.62) (p=0.024), compared to a cervical dilation of 3-4 cm. Conclusion: Majority of women undergoing MVA at MRRH experienced IPP. Younger women and those with cervical dilatation 1-2cm are more likely to experience IPP. We recommend improvement of pain control among women undergoing MVA.
Research on Denoising Method of Chinese Ancient Character Image Based on Chinese Character Writing Standard Model
Authors: Yalin MIAO , LIANG Li , Yichun JI , Guodong LI 
Published: February 2022

Abstract
Ancient documents are historical evidence of cultural inheritance, and the damage brought by natural and human factors to ancient documents is inevitable, resulting in the collected images of ancient Chinese characters containing a large amount of noise, which seriously affects the accuracy of subsequent image recognition and thus creates a great obstacle to the digitization of ancient documents. To address the complexity of ancient text structure, this paper proposes a Chinese ancient text image denoising method based on the Chinese character writing standard model.The method firstly adds four additional local branches based on the global branching, and uses the supplementary character detail information to weaken the phenomenon of strokes adhering to noise due to the lack of local details; secondly, it introduces the simulation noise of ancient documents to simulate the real ancient character image morphology, which can be used for the adversarial training of this method.In the training process, the minimum absolute value deviation, smoothing loss, structural consistency loss and the refined loss function formed by the adversarial loss are used to iteratively optimize the parameters. Finally, experiments prove that the model in this paper can increase the peak signal-to-noise ratio (PSNR) and structural similarity (SSIM) of the image by at least 23.8% and 11.4%, and the user evaluation index (UV) has also reached more than 80%.
Urinary extracellular vesicles and micro-RNA as markers of acute kidney injury after cardiac surgery
Authors: Miller Douglas , Eagle-Hemming Bryony , Sheikh Sophia , Joes-David Lathishia , Adebayo Adewale , Lai Florence , Roman Marius , Kumar Tracy , Aujla Hardeep , Murphy Gavin , Wozniak Marcin 
Published: February 2022

Abstract
Background

Secretion of extracellular vesicles (EV) and associated micro-RNAs (miR) is altered during cellular stress and may serve as biomarkers of organ injury. We hypothesized that measuring changes in urinary levels of EV and miR will predict the onset of acute kidney injury in cardiac surgery patients.
Methods

In this predictive accuracy biomarker study performed in the cohort of the REVAKI-2 trial, urine samples were collected before and 24 hours after the procedure from 93 cardiac surgery patients. Urine EV concentrations and size distribution were assessed using NanoSight. EV derivation and levels were measured using flow cytometry. Samples from 10 selected patients were sequenced to detect differentially expressed miR. Verification was performed with advanced TaqMan assays in samples from all patients.
Results

Urine EV concentrations significantly increased in patients with AKI after surgery, with the percentage of EV positive for aquaporin-2 and β1-integrin also increasing. Pre-surgery podocalyxin-positive EV were significantly lower, and β1-integrin EV were higher in patients with AKI. The levels of the former correlated with the severity of the injury. miR-125a-5p was expressed at higher levels in urine from patients with AKI stage 2/3. Levels of miR-10a-5p decreased after surgery in AKI patients; its levels correlated with the severity of the injury. Preoperative levels of podocalyxin EVs and miR-125a-5p had moderate AKI predictive value and, in a logistic model together with ICU lactate levels, offered good (AUC = 80.9%) AKI prediction.
Discussion

Urine EV concentrations and miR expression offer excellent predictive accuracy when combined with commonly measured biomarkers.
Enhanced reactivity of the CuO-Fe2O3 intimate hetero-junction for the oxidation of quinoline yellow dye (E104)
Authors: Bousalah Djedjiga , Zazoua Hanane , Boudjemaa Amel , Benmounah Abdelbaki , Messaoud-Boureghda Mohamed Zine , Bacharı Khaldoun 
Published: February 2022

Abstract
This research work was designed to study the elimination of quinoline yellow (QY) in aqueous solutions by the heterogeneous Fenton and photo-Fenton processes in the presence of CuO/Fe2O3 photocatalyst. CuO/Fe2O3 derived from LDH structure was synthesized by the co-precipitation method. The physiochemical characteristics of CuO/Fe2O3 are des cribed by XRD, TEM/SEM, BET surface area, FTIR and pHPZC.The effects of pH, H2O2 concentration, dye concentration, catalyst dose, reaction temperature, and reusability of catalyst on the QY decolorization efficiency were studied. The results indicated that a complete removal of QY was achieved within 150 min when the H2O2 and QY concentrations were 27.6 mM and 100 mg/L, respectively. The rate constants for QY removal by the heterogeneous Fenton system were calculated and the experimental data were found to fit the pseudo-first order model. Under optimal conditions, the rate constants were respectively 0.02032 and 0.02016 min-1 for the photo-Fenton and Fenton systems, this means that the addition of light has no significant effect.