bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Temporal Dynamics of Willed Attention in Vision
Authors: Nadra John G. , Bengson Jesse J. , Morales Alexander B. , Mangun George R. 
Published: April 2022

AbstractMost models of attention distinguish between voluntary and involuntary attention, the latter being driven in a bottom-up fashion by salient sensory signals. Studies of voluntary visual-spatial attention have used informational or instructional cues, such as arrows, to induce or instruct observers to direct selective attention to relevant locations in visual space in order to detect or discriminate subsequent target stimuli. In everyday vision, however, voluntary attention is influenced by a host of factors, most of which are quite different from the laboratory paradigms that utilize attention-directing cues. These factors include priming, experience, reward, meaning, motivations, and high-level behavioral goals. Attention that is endogenously directed in the absence of external cues has been referred to as self-initiated attention, or in our prior work as “willed attention”. Such studies typically replace attention-directing cues with a “prompt” that signals the subject when to choose where they will attend in preparation for the upcoming target stimulus. We used a novel paradigm that was designed to minimize external influences (i.e., cues or prompts) as to where, as well as when, spatial attention would be shifted and focused. Participants were asked to view bilateral dynamic dot motion displays, and to shift their covert spatial attention to either the left or right visual field patch at a time of their own choosing, thus allowing the participants to control both when and where they attended on each trial. The task was to discriminate and respond to a pattern in the attended dot motion patch. Our goal was to identify patterns of neural activity in the scalp-recorded EEG that revealed when and where attention was focused. Using machine learning methods to decode attention-related EEG alpha band activity, we were able to identify the onset of voluntary (willed) shifts of visual-spatial attention, and to determine where attention was focused. This work contributes to our understanding of the neural antecedents of voluntary attention, opening the door for improved models of attentional control, and providing steps toward development of brain-computer interfaces using non-invasive electrical recordings of brain activity.
Loss of the repressor REST affects progesterone receptor function and promotes uterine leiomyoma pathogenesis
Authors: Cloud Ashley S. , Koohestani Faezeh , McWilliams Michelle M. , Ganeshkumar Sornakala , Gunewardena Sumedha , Graham Amanda , Nothnick Warren B. , Chennathukuzhi Vargheese M. 
Published: April 2022

AbstractUterine Leiomyomas (UL) are benign tumors that arise in the myometrial layer of the uterus. The standard treatment option for UL is hysterectomy, although hormonal therapies such as selective progesterone receptor modulators are often used as temporary treatment options to reduce symptoms or slow the growth of tumors. However, since the pathogenesis of UL is poorly understood and most hormonal therapies are not based on UL-specific, divergent hormone signaling pathways, hallmarks that predict long-term efficacy and safety of pharmacotherapies remain largely undefined. In a previous study, we reported aberrant expression of REST/NRSF target genes activate UL growth due to the near ubiquitous loss of REST. Here, we show that ablation of the Rest gene in mouse uterus leads to UL phenotype and gene expression patterns analogous to UL, including altered estrogen and progesterone signaling pathways. We demonstrate that many of the genes dysregulated in UL harbor cis-regulatory elements bound by REST and progesterone receptor (PGR) adjacent to each other. Crucially, we identify an interaction between REST and PGR in healthy myometrium and present a putative mechanism for the dysregulation of progesterone responsive genes in UL ensuing the loss of REST. Using three Rest conditional knockout mouse lines, we provide a comprehensive picture of the impact loss of REST has in UL pathogenesis and in altering the response of UL to steroid hormones.Significance statementAblation of Rest gene in the mouse uterus, modelling the loss REST in uterine fibroids, results in tumor formation and gene expression patterns analogous to human UL, including altered estrogen and progesterone receptor (PGR) pathways. The current study provides a putative mechanism for the aberrant function of PGR in UL.
Toxoplasma scavenges mammalian host organelles through usurpation of host ESCRT-III and Vps4
Authors: Romano Julia D. , Mayoral Joshua , Guevara Rebekah B. , Rivera-Cuevas Yolanda , Carruthers Vern B. , Weiss Louis M. , Coppens Isabelle 
Published: April 2022

AbstractIntracellular pathogens exploit cellular resources through host cell manipulation. Within its nonfusogenic parasitophorous vacuole (PV), Toxoplasma targets host nutrient-filled organelles and sequesters them into the PV through deep invaginations of the PV membrane (PVM) that ultimately detach from this membrane. Some of these invaginations are generated by an intravacuolar network (IVN) of parasite-derived tubules fusing with the PVM. Here, we examine the parasite usurpation of host ESCRT-III and Vps4 to create PVM buds and vesicles. CHMP4B associates with the PVM/IVN and dominant negative (DN) CHMP4B forms many long PVM invaginations containing CHMP4B filaments; the invaginations are shorter in IVN-deficient parasites, suggesting cooperation between IVN and ESCRT. In infected cells expressing Vps4-DN, enlarged intra-PV structures containing host endo-lysosomes accumulate, reflecting defects in PVM scission. Parasite mutants lacking TgGRA14 or TgGRA64 that interact with ESCRT have reduced CHMP4B-DN-induced PVM invaginations and intra-PV host organelles, with greater defects in a double-knockout, revealing the exploitation of ESCRT to scavenge host organelles by Toxoplasma.SummaryThe parasite Toxoplasma sequesters host nutrient-filled organelles into its parasitophorous vacuole through its exploitation of host ESCRT-III and Vps4 for vacuolar membrane-remodeling and fission processes utilizing the parasite proteins TgGRA14 and TgGRA64 that interact with ESCRT.
Thermophoresis of Molecules and Structures of different Sizes in Self-assembled Biomatrices
Authors: Liu Ping , Lin Weilin , Abele Fabian , Hanke Marcel , Xin Yang , Keller Adrian , Zhang Yixin 
Published: April 2022

AbstractUpon subjecting biomolecules to non-equilibrium conditions, many biochemical and biophysical features such as biomolecular diffusion, protein folding, interaction kinetics, as well as enzyme-catalyzed reactions can be characterized in an aqueous solution. However, most assays under non-equilibrium conditions cannot be performed in complex self-assembled biomatrices (e.g. extracellular matrices) due to the limitations associated with sample handling, reaction design, and optical detection. Herein, we report the study of biomolecular thermodiffusion in non-covalently assembled synthetic or naturally derived hydrogels. This approach has been demonstrated with a large variety of analytes, including small molecules, polysaccharides, DNAs, DNA origami, and proteins in various polymer networks. The in-biomatrix method has also shown advantages over in-solution measurements: First, it allows us to analyze biomolecules in 3D matrices in a high-throughput fashion. Second, the aggregation of analytes can be remarkably prevented. Although the underlying physics of thermodiffusion is still not well-understood, we demonstrated that the thermodiffusion of surrounding networks will enhance the thermodiffusion of the analyte, an effect counteracting the hindered movement by the polymer network.
Influence of self-serving leadership on employees’ organizational deviance: a multilevel moderated mediation model
Authors: Guo Tao , Yao Nan , Zhang Lei 
Published: April 2022

Purpose
The purpose of this study is to explore the influence of self-serving leadership on employees’ organizational deviance and its internal mechanism.

Design/methodology/approach
Through the data collected from 300 supervisor–employee dyads of five large enterprises in China, this research uses multilevel structural equation model to test the proposal hypotheses.

Findings
Results show that there is a positive relationship between self-serving leadership and employees’ organizational deviance, and ego depletion plays a mediating role between them. Moreover, this research also found that the relationship between self-serving leadership and ego depletion and the indirect effect of self-serving leadership on employees’ organizational deviance through ego depletion are negatively moderated by power distance orientation.

Originality/value
This study found a new antecedent variable of employees’ organizational deviance-self-serving leadership, and based on the ego depletion theory, deeply reveals the internal mechanism of self-serving leadership influencing employees’ organizational deviance, which has some enlightening significance for relevant theoretical research and management practice. In addition, this study also has unique advantages in data collection and analysis methods.
Recovery experience of wellness tourism and place attachment: insights from feelings-as-information theory
Authors: He Mang , Liu Biqiang , Li Yaoqi 
Published: April 2022

Purpose
This study, guided by the feelings-as-information theory, aims to explore the effect of recovery experience of wellness tourism (REWT) on place attachment, alongside an examination into the mediating role of self-perceived health and the moderating role of health goal salience. The research site was traced for two years to monitor the evolution of the proposed model during the COVID-19 pandemic.

Design/methodology/approach
The successive independent samples data (in 2020 and 2021, respectively) were collected in Shizhu county, China. Structural equation modeling (SEM) was used with a survey of 1,472 wellness tourists (N2020 = 494, N2021 = 978) to test research hypotheses empirically. Additionally, independent sample t-test and multi-group SEM analysis were used to compare the mean difference of variables and coefficients’ difference between 2020 and 2021.

Findings
This study reveals that REWT can increase self-perceived health, resulting in a positive influence on place attachment. By tracing the research site and comparing the successive independent samples data, we found a stronger recovery experience effect of wellness tourism on place attachment alongside a weaker effect on self-perceived health in 2021. The positive relationship between self-perceived health and place attachment is significantly strengthened when health goals are salient.

Originality/value
This study investigated the mechanism behind the formation of place attachment in the wellness tourism context and extended understanding on the dynamic nature of the REWTand ongoing evolving person-place relationship during the COVID-19 pandemic. This study also provided practical suggestions to benefit industry practitioners by enhancing current understanding of improving experience-based management in wellness destinations.
Housing affordability: an econometric framing for policy discussions
Authors: Coskun Yener 
Published: April 2022

PurposeThe purpose of this study is to analyze short- and long-run market-sensitive drivers of housing affordability. The study highlights an ongoing housing affordability crisis in an emerging market context by also providing an empirical tool to combat the crisis.Design/methodology/approachTo investigate determinants of uniquely constructed effective housing affordability index and house price to income ratio index, the author uses a bound testing approach to cointegration and error correction models, besides causality tests, variance decompositions and impulse response functions. This study uses Turkish data for the period of 2007 M06 and 2017 M12.FindingsThe evidence suggests that the housing affordability crisis is mainly driven by credit expansion, rent and construction costs. A sensible housing policy response would target these variables. This evidence suggests that housing affordability mostly depends on housing market dynamics rather than policies because of the exogeneous/cyclical natures of the drivers.Research limitations/implicationsData constraints shape the study. A regional or an aggregate-level panel study cannot be developed because of a lack of data. This limitation inevitably results in the exclusion of relevant socio-economic/political factors and is also the main reason for the lack of comparative analysis in a cross-country setting.Practical implicationsThis study argues that dependency on neoliberal housing market practices seems the underlying reason for the lack of efficient policy answers and the ongoing affordability crisis. From a policymaking perspective, the study suggests that necessary policy measures to resolve the housing affordability crisis may give a specific emphasis on housing rent, housing credit volume and construction costs as the major components of the crisis.Originality/valueThis study develops a novel measure and presents a new conceptual framework by combining quantitative research methods and policymaking in housing affordability. In this respect, to the best of the author’s knowledge, this is the first work to comparatively investigate the determinants of uniquely developed monthly housing affordability measurements.
Institutionalisation of sustainability in Indian megaprojects: an organisational field-based approach
Authors: Thounaojam Nicola , Devkar Ganesh , Laishram Boeing 
Published: April 2022

PurposeMegaprojects have a long-lasting impact on all three dimensions of sustainability-social, environmental and economic. The advent of the COVID-19 pandemic has further heightened the importance of sustainability due to its disastrous consequences on the global economy and business activities. This study aims to explore the interactions and interventions of various actors in the megaproject field to institutionalise sustainability.Design/methodology/approachThe current study adopted the organisational field approach as the theoretical lens to understand the decision-making process amongst multiple actors with conflicting interests that come together to play an active role in addressing a common interest of sustainability in megaprojects. A single case study has been undertaken using an Indian metro rail megaproject with multiple sources of data (interviews, documents, media reports).FindingsThis study showed that the institutionalisation of sustainability is dependent on interactions of various organisations and influences from institutions. Various institutional measures organised within the field to enhance sustainability practices before and during the COVID-19 pandemic are captured. Four institutional logics (instrumental, intrinsic, equivocal and political) that emerged from the case study are discussed. Finally, while not exhaustive, this study proposed recommendations that can help refine sustainability actions considering COVID-19 implications on megaprojects.Research limitations/implicationsThis study's findings emerged from a single case study. The developed conceptual framework can help further research with multiple cases of megaprojects in various fields or countries.Originality/valueThis study would be novel in advancing the organisational field approach in megaproject sustainability.
The concept of “non-standard marriages” in the theory of family law in Russia
Authors: Anisimov Aleksey , Eltanskaya Elena , Inshakova Agnessa O. 
Published: April 2022

PurposeThe purpose of this article is to classify and study the features of the types of non-standard marriages existing in Russia (de facto, sham, same-sex marriages), in order to adjust their legal regulation by the state.Design/methodology/approachThe authors of the article examined the theoretical and practical problems of state recognition and regulation of non-standard marriages not recognized by the state, and justified a new strategy of support (in the case of de facto marriages) or counteraction (in the case of sham marriages) of these social phenomena by the state and law. In the light of the negative attitude of Russian citizens to same-sex marriages, the possibility of their support in the future is justified.FindingsHaving studied three types of non-standard marriages, the authors substantiate the need for a different approach of the state to further legal regulation of these social phenomena. It is proved, that in relation to same-sex marriages, the existing non-recognition and negative attitude of the legislator and society in Russia to their legalization will last until the attitude towards sexual minorities in general, changes in Russian society. De facto marriages should be introduced into the legal field, they should be given a normative definition and outline the general legal framework of the rights of de facto spouses and their children. As for sham marriages, it is proposed to consider the lack of intention to create a family and the selfish interest to be their main features pursued by one or both spouses entering into a sham marriage.Originality/valueThe originality and value of the research is stipulated by the consideration of the legal regulation of marriage and family issues in the historical context of the development of the Russian state, as well as the evolution of ideas about morality in Russian society. The changing attitude of society towards de facto marriages, the increase in the number of unregistered married couples indicates the transformation of the moral values of young people and the need for the state to promote the legal protection of such married couples without trying to prohibit or restrict them. Existing approaches to the legal regulation of sham marriages require adjustments, including incorporating the notion of “fictitious divorce” in family legislation.
Purpose vs mission vs vision: persuasive appeals and components in corporate statements
Authors: Fitzsimmons Alexis Bajalia , Qin Yufan Sunny , Heffron Eve R. 
Published: April 2022

PurposePurpose statements persuade stakeholders of companies' reasons for being. The goal of this study was to analyze how purpose-driven companies craft their purpose, mission and vision statements and whether and how purpose statements differ from mission and vision statements.Design/methodology/approachThis quantitative content analysis explored the brand personality traits, mission statement components and corporate ethos appeals that purpose-driven companies included in their purpose, mission and vision statements.FindingsResults provide implications for corporate leaders and communicators who write these statements as well as theoretical implications related to brand personality, rhetorical theory and corporate ethos.Practical implicationsThis research provides practical implications for corporate leaders and communication professionals about how to craft these statements, what components they might include and the potential benefits and downfalls of not clearly differentiating among purpose, mission and vision statements.Originality/valueWhile several studies have compared differences between mission and vision statements, there is a lack of academic literature on how companies craft purpose statements. This study added to this body of knowledge on corporate communication.
When librarians speak up: justifications for and legitimacy implications of librarians' engagement in social movements
Authors: Kann-Rasmussen Nanna 
Published: April 2022

PurposeThis article presents a discussion of how librarians' engagement in certain social movements manifests itself in public libraries, how librarians justify their engagement with specifically the LGBT + movement and the climate movement and what it might entail in terms of legitimacy.Design/methodology/approachBesides an extensive international literature on libraries and climate/LGBT + issues, the article draws on data from an interview study with librarians from Denmark and Sweden. Theoretically, the article utilizes the orders of worth framework by French sociologists Boltanski and Thévenot. The framework is used to analyse librarians' justifications for engaging in certain agendas in society.FindingsActive engagement in social and green agendas takes place through strategies of education, efforts to make the cause more visible in the library and by setting an example. Justifications for active engagement in social movement agendas draw on inspirational, civic, projective and green orders of worth (OoW).Originality/valueMuch of the existing research on librarians who engage themselves in either climate issues or in agendas concerning minorities has a normative character. However, this study shows that there is no causal (positive or negative) relation between active engagement in social movements' causes and legitimacy of libraries, but that the justifications for doing so might have an impact on legitimacy.
School leadership and achievement gaps based on socioeconomic status: a search for socially just instructional leadership
Authors: Gümüş Sedat , Bellibaş Mehmet Şükrü , Pietsch Marcus 
Published: April 2022

PurposeThe research literature in this field demonstrates that instructional leadership provided by principals is essential for student learning, but the question of its impact on students with high and low socioeconomic status (SES) has remained largely unexplored. In the present study, the authors focus on the moderating role of instructional leadership in the relationship between SES and achievement at both the school and student levels.Design/methodology/approachUsing cross-national Programme for International Student Assessment (PISA) 2015 data, the authors fitted multilevel models to investigate whether the effect of instructional leadership on student achievement in math, science and reading varies across groups of students with the different individual as well as school SES levels.FindingsInstructional leadership significantly moderates the relationship between school-level SES and student achievement in math, while the moderation effect for individual SES and instructional leadership is not significant for any subject.Research limitations/implicationsThis study calls for more research on the moderation role of leadership in the relationship between SES and student achievement, with a specific focus on the integrated models that include the social justice aspect of school leadership.Originality/valueThe authors conclude that while instructional leadership might be beneficial in reducing the achievement gaps between schools, it may not make much difference in terms of reducing the disparity between different SES groups within schools.