bluuebunny/crossref_metadata_2025_split huggingface dataset:
Response to Letter to Editor From the Canadian Stroke Consortium
Authors: Dunfield Lesley 
Published: September 2022

We thank the Canadian Stroke Consortium Policy and Advocacy Committee for its Letter to the Editor regarding the Rapid Review on Systemic Thrombolysis by Alteplase for Acute Ischemic Stroke.
Many of the concerns raised were related to the limitations of the methods and processes used for CADTH Rapid Reviews, which use abbreviated systematic review methods to complete syntheses in accelerated time frames.
While care is taken to ensure the work is complete and up to date within Rapid Review methods and processes, Rapid Reviews are not comprehensive systematic reviews and are not intended to be used as substitutes for clinical or professional judgment.
Dostarlimab (Jemperli)
Authors: CADTH  
Published: September 2022

CADTH recommends that Jemperli should not be reimbursed by public drug plans for monotherapy for the treatment of adult patients with mismatch repair deficient (dMMR) or microsatellite instability-high (MSI-H) recurrent or advanced endometrial cancer (EC) that has progressed on or following prior treatment with a platinum-containing regimen.
While evidence from a clinical trial demonstrated that some patients had disease that responded during treatment with Jemperli, without a control group there is uncertainty in how much the observed responses were due to Jemperli treatment rather than chance.
There was too much uncertainty in the reviewed evidence to determine how Jemperli compares to other treatments used in Canada.
It is unclear whether Jemperli meets the following needs identified by patients: improved tumour response, delayed disease progression, improved quality of life, and fewer side effects.
Avalglucosidase Alfa (Nexviazyme)
Authors: CADTH  
Published: September 2022

CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.
This review assesses Avalglucosidase alfa (Nexviazyme), 100 mg/vial, 20 mg/kg of body weight, administered every other week by IV infusion.
Indication: Nexviazyme (avalglucosidase alfa) is an enzyme-replacement therapy indicated for the long-term treatment of patients with late-onset Pompe disease (LOPD) (acid alpha-glucosidase deficiency).
Impacts of condensable particulate matter on atmospheric organic aerosols and fine particulate matter (PM2.5) in China
Authors: Li Mengying , Yu Shaocai , Chen Xue , Li Zhen , Zhang Yibo , Song Zhe , Liu Weiping , Li Pengfei , Zhang Xiaoye , Zhang Meigen , Sun Yele , Liu Zirui , Sun Caiping , Jiang Jingkun , Wang Shuxiao , Murphy Benjamin N. , Alapaty Kiran , Mathur Rohit , Rosenfeld Daniel , Seinfeld John H. 
Published: September 2022

Abstract. Condensable particulate matter (CPM) emitted from stationary combustion and
mobile sources exhibits high emissions and a large proportion of organic
components. However, CPM is not generally measured when conducting emission
surveys of PM in most countries, including China. Consequently, previous
emission inventories have not included emission rates for CPM. Here, we
construct an emission inventory of CPM in China with a focus on organic
aerosols (OAs) based on collected CPM emission information. Results show that
OA emissions are enhanced twofold after the inclusion of CPM in a new
inventory for China for the years 2014 and 2017. Considering organic CPM emissions and
model representations of secondary OA (SOA) formation from CPM, a
series of sensitivity cases have been simulated here using the three-dimensional
Community Multiscale Air Quality (CMAQ) model to estimate the contributions
of CPM emissions to atmospheric OA and fine PM (PM2.5, particulate matter with
aerodynamic diameter not exceeding 2.5 µm) concentrations
in China. Compared with observations at a Beijing site during a haze episode from 14 October
to 14 November 2014, estimates of the temporal average
primary OA (POA) and SOA concentrations were greatly improved after including
the CPM effects. These scenarios demonstrated the significant contributions
of CPM emissions from stationary combustion and mobile sources to the POA (51 %–85 %​​​​​​​), SOA (42 %–58 %), and total OA
concentrations (45 %–75 %). Furthermore, the contributions of
CPM emissions to total OA concentrations were demonstrated over the 2 major
cities and 26 other cities of the Beijing–Tianjin–Hebei region (hereafter referred to as the “BTH2 + 26 cities”) in December 2018, with average contributions of up to 49 %, 53 %, 54 %, and 50 %
for Handan, Shijiazhuang, Xingtai, and Dezhou, respectively.
Correspondingly, the inclusion of CPM emissions also narrowed the gap
between simulated and observed PM2.5 concentrations over the BTH2 + 26
cities. These results improve the simulation performance of atmospheric OA
and PM2.5 and may also provide important implications for the sources of
OA.
Using a process-based dendroclimatic proxy system model in a data assimilation framework: a test case in the Southern Hemisphere over the past centuries
Authors: Rezsöhazy Jeanne , Dalaiden Quentin , Klein François , Goosse Hugues , Guiot Joël 
Published: September 2022

Abstract. Currently available data-assimilation-based reconstructions of past climate variations have only used statistical proxy system models to make the link between climate model outputs and indirect observations from tree rings. However, the linearity and stationarity assumptions of the statistical approach may have limitations. In this study, we incorporate the process-based dendroclimatic model MAIDEN into a data assimilation procedure using the reconstruction of near-surface air temperature, precipitation and winds in the midlatitudes of the Southern Hemisphere over the past 400 years as a test case. We compare our results with a data assimilation approach including a linear regression as a proxy system model for tree-ring width proxies. Overall, when compared to instrumental data, the reconstructions using MAIDEN as a proxy system model offer a skill equivalent to the experiment using the regression model. However, knowing the advantages that a process-based model can bring and the improvements that can still be made with MAIDEN, those results are promising.
THE EFFECT OF USING WEB-BASED ELECTROCARDIOGRAPHY SIMULATION ON RHYTHM DIAGNOSTIC SKILLS OF PARAMEDIC STUDENTS
Authors: KURTGÖZ Asli , KESKİN Selin 
Published: September 2022

Objective: This study was conducted to determine the effect of the use of web-based electrocardiography (ECG) simulation on paramedic students' rhythm diagnostic skills.
Method: The study was conducted as a single-group pretest-posttest design study between 02.05.2021-01.09.2021. The study group of the research consisted of students studying in the last year in the paramedical department of a university in Turkey. The data of the study were collected person-to-person using the information form and the Basic ECG Rhythm Diagnosis Form. Participants were provided online ECG training for 3 hours per week over the course of 8 weeks. One month after the training, the participants were pre-tested. After the pretest, the participants used a web-based ECG simulator for 4 weeks. Posttest was applied to the participants at the end of four weeks.
Results: It was found that the rate of correct diagnosis of all rhythms in the Diagnosis of Basic ECG Rhythms Form of the students increased after the use of a web-based simulator. It was determined that there was a significant statistical difference between the pre-test and post-test scores of the students (t:-7.476, p
أوميكرون اضطراب الكرب الحاد خلال متحوّر أوميكرون (B.1.1.529) في ضوء بعض المتغيرات الديمغرافية دراسة عامليه لدى عينه من المجتمع السعودي
Authors: Elshokheby Asmaa Mostafa 
Published: September 2022

تهدف الدراسة إلى التحقق من التحليل العاملي الاستكشافي لمقياس اضطراب الكرب الحاد خلال متحوّر أوميكرون في ضوء بعض المتغيرات الديمغرافية لدى عينه من المجتمع السعودي. قامت الباحثة بإعداد المقياس وتم تطبيقه على عينة عشوائية تكونت من 802 مشارك من المجتمع السعودي (مقسمين إلى 555 إناث، و247 ذكور. تم تقسيم أعمار المشاركين إلى (من 18-29) (30- 39) (40 -49) (50 عاما فأكثر) من المستوى التعليمي (غير جامعي- بكالوريوس- ماجيستير- دكتوراه)، تم التطبيق في ديسمبر 2021، اعتمدت الدراسة لتحقيق أهدافها على المنهج الوصفي، وأجريت الاستبيانات إلكترونيا لجميع أفراد عينة الدراسة، وتم جمع البيانات باستخدام الأساليب الإحصائية الملائمة أظهرت نتائج الدراسة وجود خمس عوامل كان جذرها الكامن أكبر من واحد صحيح. وجود فروق دالة إحصائيا في اضطراب الكرب الحاد تعزى لمتغير الجنس (ذكر، أنثى) لصالح الإناث. وجود فروق دالة إحصائيا في اضطراب الكرب الحاد تعزى لمتغير المستوى التعليمي. وجود فروق دالة إحصائيا عند في اضطراب الكرب الحاد تعزى لمتغير العمر، وفي نهاية الدراسة تم تقديم بعض التوصيات هي: التقليل من التعرض للأخبار السلبية والتي قد تؤدي إلى زيادة الإحساس بالهلع، محاولة تعلم هوايات جديدة أو خلق روتين جديد حتى انتهاء هذه الفترة ، التفاؤل، فعلى الرغم من الوضع الحالي، إلا أن الإنسان من الممكن أن يلتفت لقيمة اللحظة الحالية وقيمة الصحة، مساعدة الآخرين، والخروج خارج الذات، وهو الأمر الذي يظهر في تكاتف الكثيرين لمساعدة البعض، التعبير عن مشاعر الغضب أو الآلام النفسية والتحدث عنها لأن الكبت قد يؤدي إلى اكتئاب أو زيادة الأمراض النفسية والتي قد لا تظهر أثارها الآن، ممارسة تمارين التأمل أو ممارسة أي نوع من التمارين الرياضية.
Tricolporate pollen of caesalpiniaceae medicinal plants at Kotla Vijaya Bhaskara Reddy botanical garden in Cyberabad, Telangana
Authors: Kumar Y. , Ramakrishna H. , Devender R. 
Published: September 2022

This paper presents the study of a tricolporate pollen morphology of 08 Caesalpiniaceae medicinal plant taxa viz. Bauhinia purpurea L., Caesalpinia pulcherrima( L.) SW.,Cassia fistula L., Delonix regia (Hook.) Raf., Peltophorum pterocarpum (DC.) K.Heyne., Senna auriculata L., S. sophera (L.), Roxb. and Tamarindus indica L. The flower buds of these plants were collected from blocked category of Cyberabad area i.e. Kotla Vijaya Bhaskara Reddy Botanical Garden. By using Erdtman’s (1960) acetolysis technique, the collected flower buds were processed. The result of the study showed that Caesalpiniaceae tricolporate pollen grains have diversity in their pollen morphological characters like Polarity, Symmetry, Shape, Aperture and Sporoderm. The observations of this study will be useful for authentic identification of the taxa of Caesalpiniaceae.
Root amputation
Authors: Garg Arun , Neetu Neetu , Kumar Ravi , Motwani Niraj 
Published: September 2022

Decision making in endodontic failure tooth between resective procedure or extraction with implant is still challenge for clinicians. The rising concern of the patients towards preserving the natural dentition may shift the clinicians towards Root resection, root amputations and hemisection. Proper case selection is the key to success of resective treatment. This case report describe and illustrates one of the treatment option that is root amputation in tooth with endodontic failure.
Together for good: Aspects of supportive communication between tertiary classmates that lead to academic success
Authors: Mock Andrew , Hodis Georgetta 
Published: September 2022

How well classmates communicate support with each other may significantly influence how well they learn and their commitment to learning. This study asked students which aspects of supportive communication they use with each other and which aspects they regard as most important for successful study. One hundred polytechnic students participated in this study. They rated how frequently they experienced and how influential they considered 18 aspects of supportive communication between classmates for study success. The students regarded many aspects of supportive communication influential but few aspects were present in most instances. They experienced and valued able and motivated supporters, and supportive relationships with classmates the most. Students in similar years of study experienced and valued similar aspects of supportive communication. Training a whole class in supportive communication may develop positive shared values among the students and a climate that encourages mutual support. Courses that provide ongoing activities and opportunities for students to develop their skills in communicating support may produce more successful students.
An Overview of Tree Species Used for Agroforestry Practices in Nepal
Authors: Budha Sher Bahadur 
Published: September 2022

Tree species are the main component of the agro-forestry system because they provide farmers with direct benefits and play a vital role in mitigating climate change, stabilizing slopes, and ecological balance. The list of tree species used in different agro-forestry practices shows 110 tree species belonging to 42 families. Tree species belonging to the family Moraceae are widely used in agro-forestry practices, followed by Liguminosae, Rosaceae, Rubiaceae, and so on. There are approximately 44 species of trees suitable for single use, such as forage, fruit, fuelwood, and timber production. Similarly, tree species with two functions are better than tree species with only one function. Approximately 40 trees have two functions: food and fuelwood, fruit and fuelwood, and wood and fuelwood. Among the 110 species used in agro-forestry practices in Nepal, 21 species have more than two functions and are the most suitable species for agro-forestry practices. The use of tree species in different agro-forestry practices shows that the number of trees used in Silvo-pastoral systems is the highest (30%), followed by Horto-agri-silviculture (23%). Approximately 21% of tree species are used in more than two agro-forestry systems. The minimum number of tree species used for Agri-silvi-pastoral and home gardens is 3% and 4% respectively.
Phasing out coal through electricity market regulation
Authors: Boute Anatole 
Published: September 2022

The use of coal for power generation is incompatible with the EU decarbonization objective, but prohibiting it remains a national prerogative, in view of Member States’ right to determine their energy fuel mix. Instead, the EU relies on market forces to drive the decarbonization of electricity supply. Building on the theory on the interactions of carbon and electricity pricing, this article examines how EU electricity law interacts with the EU Emissions Trading System (ETS) to facilitate the phase-out of coal power. In line with the theory, the legal architecture governing the liberalization of the EU electricity market plays a crucial, but much overlooked, role in the EU decarbonization approach by neutralizing regulatory obstacles to the influence of the ETS on investment and closure decisions. The renewed competitiveness of coal power in the context of the 2021–2022 energy crisis emphasized the economic unpredictability associated with this market-based approach. However, calls for market reform must be considered with caution given the complex interactions of electricity and carbon pricing, and the potentially destabilizing effect of regulatory interference with the market architecture created to drive decarbonization within EU constitutional powers.
decarbonization, coal-fired power generation, EU electricity law, EU Emissions Trading System, fossil fuel subsidies
‘Code of Absence’: EU-Belarus Legal Framework
Authors: Miadzvetskaya Yuliya 
Published: September 2022

It is usually considered that EU-Belarus contractual relations are almost non-existent due to the lack of an overarching agreement between the parties. This article argues that the EU-Belarus contractual relations, despite their apparent absence, consist of a complex system of legal instruments. The article identifies three main intrinsic characteristics of the EU-Belarus bilateral framework: quasi-institutionalization of the political dialogue as well as preponderance of unilateral ‘soft’ instruments and sector-specific cooperation. This quasi-legal framework has concrete implications for the (limited) toolbox available for the EU to respond to the migrant crisis at its borders with Belarus. In addition to EU internal measures to counter migrant smuggling, the partial suspension of the Visa Facilitation Agreement and the upgrading of the EU restrictive measures emerged as two available legal avenues for the EU’s action with respect to Belarus.
Belarus, Eastern Partnership, PCA, legal framework, ENP, Readmission Agreement, Visa Facilitation Agreement, Customs cooperation
Paradox or Pressure? Consumer Expectations and the Australian Privacy Act
Authors: Manwaring Kayleen 
Published: September 2022

This article outlines the empirical evidence in Australia regarding consumer privacy expectations as to commercial dealings with their data. Despite widespread disclosure of personal information from consumers to businesses, the evidence indicates that consumers believe that their privacy is important, and their personal information should be protected from misuse. However, this so-called ‘privacy paradox’, where consumer behaviour in ‘consenting’ to substantial data collection of personal information is not, in fact, a paradox. Rather, it is explained by consumers’ expectations and perceptions around data collection and handling by commercial entities: most importantly a perception by many that they have little or no choice or control over their personal information. It also shows that they expect the legal system to protect them against misuse of that data. With these expectations in mind, the article proceeds to introduce key parts of the general framework of the Privacy Act 1988 (Cth) under which digital data practices are currently regulated in Australia.
Australia, Data Protection, Privacy, Consumers, Privacy Paradox
Informed Consent to Online Standard Form Agreements
Authors: Nicholls Rob 
Published: September 2022

This article examines the issues associated with online consent to ‘take it or leave it’ contracts, also known as standard from agreements. It does this by describing the concepts of standard form agreement and their deviations from bilateral contracts. It also sets out the meaning of informed consent. With these concepts established, the article analyses informed consent in online standard form agreements and provides an analysis of the factors impacting informed consent. The article also draws a distinction between unfairness and unconscionability.
The article demonstrates that courts and regulators look the other way when it comes to recognizing substantive unfairness and unconscionability in online standard form agreements. It discusses the legal, economic, behavioural and social dynamics of informed consent in the context of the Australian marketplace. The article demonstrates that, in Australia, the focus on procedural unfairness and procedural unconscionability as threshold requirements have prevented the notion of informed consent from voiding particular terms. That is, as long as there was notice and an opportunity to read, in Australia the actual content of the terms seems to have limited importance.
Australia, Standard Form Agreements, Unconscionability, Unfairness, Informed Consent
Reform in Australia: A Focus on Informed Consent
Authors: Nicholls Rob 
Published: September 2022

This article analyses the Australian privacy framework in the context of both the Australian Competition and Consumer Commission’s Digital Platforms Inquiry (DPI) and the Consumer Data Right (CDR). This analysis extends to informed consent and attitudes to unfairness and unconscionability. The article offers potential solutions to the current patchwork approach which go further than the Government response to the DPI. It argues that the Australian Government’s response is not an adequate response nor a set of suitable solutions to the problem.
The article proposes a two-pronged approach that recognizes the urgency of the issue through the suggestion of a series of ‘quick policy wins’ that will result in more meaningful and effective protection for consumers and further systemic, long-term recommendations for change that can be achieved through policy development, further consultation and integration with other existing legislation. The quick policy wins centre on three specific changes, including definitional updates, content and structure of online standard form agreements and enforcement, penalties and sanctions, and long-term solutions. The long-term solutions are proposed to include regulation of website design, better integration of the laws, regulators and enforcement bodies, a faster, more consistent pace of policy review and recognition of the societal and human benefit of informed consent to online standard form agreements.
Australia, Digital Platforms, Consumer Data Right, Informed Consent, Reform
What does ICT help and does not help?
Authors: Jakab Enikő 
Published: September 2022

Year by year, ICT tools and related teaching methods are evolving a lot. Since 2016, the author of the present lines has been looking for a connection between them that supports the development of mathematical competencies and could be integrated into Transcarpathian minority Hungarian language education too. As a doctoral student at the University of Debrecen, I experienced, for example, how the interactive whiteboard revolutionized illustration in Hungarian mathematics teaching, and how it facilitated students' involvement. During my research of teaching in this regard, in some cases, the digital solution had advantageous effects versus concrete-manipulative representation ofBruner's too.At the same time, ICT "canned" learning materials (videos, presentations, ...) allow for a shift towards repetitive learning instead of simultaneous active participation, which can be compensated for by the "retrieval-enhanced" learning method.I have conducted and intend to conduct several research projects in a Transcarpathian Hungarian primary school. In the research so far, I examined whether, in addition to the financial and infrastructural features of the Transcarpathian Hungarian school, the increased "ICT-supported" and the "retrieval-enhanced" learning method could be integrated into institutional mathematics education. I examined the use of two types of ICT devices: one was the interactive whiteboard, and the other was providing one computer per student.In this article, I describe my experiences, gained during one semester, in the class taught with the interactive whiteboard on the one hand, and in the class taught according to the "retrieval-enhanced" learning method on the other hand.I compare the effectiveness of the classes to their previous achievements, to each other, and to a class in Hungary.
Subject Classification: 97U70