bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hemodynamics of self-expanding versus balloon-expandable transcatheter heart valves in relation to native aortic annulus anatomy
Authors: Schmidt Sarah , Fortmeier Vera , Ludwig Sebastian , Wienemann Hendrik , Körber Maria Isabel , Lee Samuel , Meertens Max , Macherey Sascha , Iliadis Christos , Kuhn Elmar , Eghbalzadeh Kaveh , Bleiziffer Sabine , Baldus Stephan , Schofer Niklas , Rudolph Tanja Katharina , Adam Matti , Mauri Victor 
Published: June 2022

Abstract
Objectives
This study aimed to compare hemodynamic characteristics of different self-expanding (SE) and balloon-expandable (BE) transcatheter heart valves (THV) in relation to native aortic annulus anatomy.

Background
A patient centered THV selection becomes increasingly important as indications for transcatheter aortic valve replacement (TAVR) are extended towards lower risk populations.

Methods
Hemodynamic parameters including mean gradient (MG), effective orifice area (EOA), Doppler velocity index (DVI), degree of paravalvular regurgitation (PVR) and patient-prosthesis mismatch (PPM) were compared by valve type, label size and in relation to quintiles of native aortic annulus area.

Results
2609 patients were treated at 3 centers in Germany with SAPIEN 3 (n = 1146), ACURATE Neo (n = 649), Evolut R (n = 546) or Evolut Pro (n = 268) THV. SE THVs provided superior hemodynamics in terms of larger EOA, higher DVI and lower MG compared to BE THV, especially in patients with small aortic annuli. Severe PPM was less frequent in SE treated patients. The rate of PVR ≥ moderate was comparable for SE and BE devices in smaller annular dimensions, but remarkably lower for BE TAVR in large aortic annular dimensions (> 547.64 mm2) (2% BE THV vs. > 10% for SE THV; p < 0.001).

Conclusions
Patients with small aortic annular dimensions may benefit hemodynamically from SE THV. With increasing annulus size, BE THV may have advantages since PVR ≥ moderate occurs less frequently.

Graphical abstract
In vitro grafting of hepatic spheroids and organoids on a microfluidic vascular bed
Authors: Bonanini Flavio , Kurek Dorota , Previdi Sara , Nicolas Arnaud , Hendriks Delilah , de Ruiter Sander , Meyer Marine , Clapés Cabrer Maria , Dinkelberg Roelof , García Silvia Bonilla , Kramer Bart , Olivier Thomas , Hu Huili , López-Iglesias Carmen , Schavemaker Frederik , Walinga Erik , Dutta Devanjali , Queiroz Karla , Domansky Karel , Ronden Bob , Joore Jos , Lanz Henriette L. , Peters Peter J. , Trietsch Sebastiaan J. , Clevers Hans , Vulto Paul 
Published: June 2022

AbstractWith recent progress in modeling liver organogenesis and regeneration, the lack of vasculature is becoming the bottleneck in progressing our ability to model human hepatic tissues in vitro. Here, we introduce a platform for routine grafting of liver and other tissues on an in vitro grown microvascular bed. The platform consists of 64 microfluidic chips patterned underneath a 384-well microtiter plate. Each chip allows the formation of a microvascular bed between two main lateral vessels by inducing angiogenesis. Chips consist of an open-top microfluidic chamber, which enables addition of a target tissue by manual or robotic pipetting. Upon grafting a liver microtissue, the microvascular bed undergoes anastomosis, resulting in a stable, perfusable vascular network. Interactions with vasculature were found in spheroids and organoids upon 7 days of co-culture with space of Disse-like architecture in between hepatocytes and endothelium. Veno-occlusive disease was induced by azathioprine exposure, leading to impeded perfusion of the vascularized spheroid. The platform holds the potential to replace animals with an in vitro alternative for routine grafting of spheroids, organoids, or (patient-derived) explants.
Can Job Stressors Activate Amoral Manipulation? A Weekly Diary Study
Authors: Ma Gloria Xiaocheng , Petrou Paraskevas , Bakker Arnold B. , Born Marise Ph. 
Published: June 2022

AbstractThis study investigates whether job stressors such as role ambiguity, procedural unfairness, and perceived competition may prompt high Machiavellian employees to use amoral manipulation at work. We also examine whether these manipulative behaviors are consequently related to their own task performance and affiliative citizenship behaviors. A weekly diary study was conducted among 111 Dutch employees over five consecutive working weeks, resulting in 446 assessed occasions. Using a multilevel moderated mediation model, we found that the relationship between weekly job stressors and weekly amoral manipulation (AM) was contingent on trait AM, when the job stressor was role ambiguity (but not when the job stressor was either weekly procedural unfairness or weekly perceived competition). Our results also revealed significant indirect effects of weekly role ambiguity on weekly task performance and weekly display of courtesy through state AM, when trait AM was high. Our findings suggest that role ambiguity activates high Machiavellian employees’ manipulative behaviors at work, which in turn leads to impaired task performance and less courtesy toward others during the same working week.
Stability assessment for selection of elite sugarcane clones across multi-environment based on AMMI and GGE-biplot models
Authors: Mehareb Eid M. , Osman M. A. M. , Attia A. E. , Bekheet M. A. , Abo Elenen Fouz F. M. 
Published: June 2022

AbstractSeven field experiments were conducted at three experiment stations representing major sugarcane producing regions in Egypt. Each experiment comprised a randomized complete block design with three replications. Fourteen elite breeding lines typical of those routinely generated in the three final selection stages of sugarcane breeding programs in Egypt, along with one check variety (GT54-9) were evaluated for cane and sugar yield in this study during the 2018/2019, 2019/2020 and 2020/2021 seasons. Stability parameters including cultivar stability rank and superiority index were determined. The data was also investigated using GGE-biplots, the additive main effects and multiplicative interaction model (AMMI), and the AMMI stability value (ASV). The genotype main effect was used to visualize the G x E interaction. The results of these trials are of significance in guiding the selection and recommendation of superior sugarcane varieties and more stable in sugarcane production zones. The clone G.2016–129 had a mean sugar yield and cultivar superiority index for sugar yield exceeding that of GT54-9, and hence was recommended for commercial planting. Because of local conditions in Egypt, an elite sugarcane variety would have high and stable yield and would adapt to a wide range of environments. In the present study, only one clone G.2016–129 fit that definition by producing higher and more stable sugar yield than the commercial variety GT 54–9.. At the side of multivariate analyses, the ASV (AMMI stability value) supports selection of stable varieties in the AMMI Method. Varieties with lowest ASV are stable. Therefore, the results of this study exposed that G.2016–95, F-150 and G.2016–129 with lowest ASV for cane yield by contrast, G.2009–11, G.2016–128, F-150 and G.2016–95 with lowest ASV for sugar yield, were stable clones for cane and sugar yields, respectively.
Maternal epigenetic responsibility: what can we learn from the pandemic?
Authors: Turkmendag Ilke , Liaw Ying-Qi 
Published: June 2022

AbstractThis paper examines the construction of maternal responsibility in transgenerational epigenetics and its implications for pregnant women. Transgenerational epigenetics is suggesting a link between maternal behaviour and lifestyle during pregnancy and the subsequent well-being of their children. For example, poor prenatal diet and exposure to maternal distress during pregnancy are linked to epigenetic changes, which may cause health problems in the offspring. In this field, the uterus is seen as a micro-environment in which new generations can take shape. Because epigenetics concerns how gene expression is influenced by the social realm, including a range of environmental conditions such as stress, diet, smoking, exercise, exposure to chemicals, pollution, and environmental hazards, the research findings in this area have direct policy relevance. For policy makers, rather than controlling this complex range of determinants of health, isolating and targeting maternal body and responsibilising mothers for the control of this micro-environment might seem feasible. Yet, examining the maternal body in isolation as a powerful environment to shape the health of next generations not only responsibilises women for the environment that they cannot control but also makes them a target for intrusive and potentially exploitative biomedical interventions. Even though ‘social factors’ are increasingly considered in epigenetics writing, the phrase is usually taken as self-explanatory without much elaboration. Drawing on the Covid-19 pandemic, this paper moves the current debate forward by providing consolidated examples of how individuals, including pregnant women, have little control over their environment and lifestyle. As evidenced by the pandemic’s disproportionate effects on people with low socioeconomic or poor health status, some pregnant women bore considerable physical and psychological stress which combined with other stress factors such as domestic violence.
Refugee entrepreneurship: systematic and thematic analyses and a research agenda
Authors: Abebe Solomon Akele 
Published: June 2022

AbstractRefugee entrepreneurship has recently entailed increased scholarly mobilization and drastic growth in the volume of salient scientific research. However, this emerging research stream is marked by fragmentation and incoherence, primarily due to the multidisciplinary and context-specific nature of its extant findings. While this process is natural for emerging fields, the current state of research necessitates a comprehensive review, synthesis, and organization of its subject matter. Hence, this study systematically and thematically explores the landscape of refugee entrepreneurship research and its intellectual territory across diverse disciplines to take stock of a repository of the literature and trace its emergence, nature, and development. By analyzing 131 publications, this paper thus lays a collective research foundation for building a coherent theory, making incremental adjustments, and forming the ontological and epistemological basis for refugee entrepreneurship research. The study also identifies gaps in the literature and opens pathways for future scholarly endeavors.
Unexpected events during survey design and trust in the police: a systematic review
Authors: Nägel Christof , Nivette Amy E. 
Published: June 2022

Abstract
Objectives
The current review has two aims: (1) to synthesize the impact of unexpected events on trust in police across different contexts and types of events, and (2) to evaluate the methodological characteristics of each study with attention to the assumptions for causal inference.

Methods
We conducted a pre-registered narrative systematic review on 12 independent studies.

Results
Studies closely adhering to causal inference assumption checks (i.e., excludability and ignorability) find significant changes in trust in police following incidents of police (non) violence and protest. Still, excludability is assessed and addressed less rigorously than ignorability in the included studies.

Conclusion
Regarding the procedural justice framework, this provides some causal evidence that vicarious (positive and negative) experiences can shape short-term assessments of public trust in police. We furthermore highlight issues related to design and power, statistical conclusion validity, and the evaluation of assumptions to detect threats to internal validity.
Monitoring effect of nickel, copper, and zinc on growth and photosynthetic pigments of Spirulina platensis with suitability investigation in Idku Lake
Authors: Kaamoush Mona , El-Agawany Nagwa , Salhin Hamida El , El-Zeiny Ahmed 
Published: June 2022

Abstract
Owing to the increase of pollutant sources in oceans, seas, and lakes, there is an expected effect on growth and metabolism of planktonic algae which are considered primary producers in the ecosystem. Therefore, it becomes urgent to carry out laboratory studies to test to what extent these pollutants can affect the growth of algae which is necessary as a food for marine fishes. Spirulina is considered the most important algal species due to its high nutritional value for humans and animals. Therefore, this work investigated the effect of different concentrations of Ni2+, Zn2+, and Cu2+ metal ion pollutants on growth of the blue-green alga Spirulina platensis. EC50 was identified to be around 2 mg/l for the three heavy metals. The suitability of Idku Lake for Spirulina platensis growth was investigated using multi-criteria spatial modeling integrated with remotely sensed data processing. Spatial distribution maps of turbidity, water nutrients, and phytoplankton were the input criteria used to assess Idku Lake’s suitability. The results obtained proved that low concentrations of the tested heavy metals stimulated growth and pigment fractions (chlorophyll a, carotenoids, and total phycobilins content) but to different degrees. The inhibitory effect was more prominent in the case of copper ions than zinc and nickel ions with all concentrations used. The overall suitability map of Spirulina platensis in Idku Lake showed that the whole lake is suitable for growth and proliferation except for the northwestern corner due to the high salinity levels. The present paper helps to understand the behavior of algae responding to environmental pollution, which supports environmental planners with the necessary baseline for investigating the fate of pollutants and the potential risk.
Entrepreneurial decision-making perspectives in transition economies – tendencies towards risky/rational decision-making
Authors: Melović Boban , Veljković Slavica Mitrović , Ćirović Dragana , Vulić Tamara Backović , Dabić Marina 
Published: June 2022

AbstractThis paper assesses the ways in which the characteristics of entrepreneurs from transition economies, and the extent to which they participate in making business decisions, affect their propensity to make rational/risky decisions in a work environment. A multicontextual analysis of entrepreneurial decision-making is provided, facilitating a better understanding and the further advancement of entrepreneurship in the transition countries of Montenegro and Serbia. Logistic regression and a Structural Equation Model (SEM) were used to assess data collected from a stratified random sample of 260 entrepreneurs. The results reveal that the demographic characteristics of entrepreneurs have a significant impact on their propensity to make rational/risky decisions. Elderly entrepreneurs with more years of service are more prone to make rational decisions in comparison to younger entrepreneurs, who lack business experience and thus rely on intuition, leading to risky decision-making. Additionally, the results show that the more involved entrepreneurs are in the decision-making process, the more risky decisions will be made; while more employee inclusion leads to business decisions based on rational thinking. The results also reveal that entrepreneurs in transition economies have formed attitudes towards the nature of entrepreneurial activity. Finally, these results reveal that entrepreneurs who consider levels of economic development, national culture, and intuition to be important when making business decisions are more prone to implement risky decisions. Considering the obtained results, this paper provides guidelines for the future research of this issue in transition countries and other developing economies.
Employee mobility and service-related management in the carbon footprint of services—German case studies
Authors: Pelzeter Andrea 
Published: June 2022

AbstractPurposeIn a service society, the assessment of climate-relevant environmental impacts of services is of increased importance. In the few Product Category Rules (PCRs) for cleaning services available to date, it is noticeable that employee mobility and service-related management are excluded from the assessment. This practice is critically questioned in the following study. The aim is to show that a calculation of the carbon footprint of services that integrates employee mobility and service-related management provides a better basis for finding ways to reduce their environmental impact.MethodsKey figures on the CO2e emissions of services are examined in exemplary case studies using the example of cleaning, maintenance and reception with regard to the possible share of emissions caused by employee mobility and service-related management activities. For the case studies located in Germany, characteristic values of the equipment, operating materials or mobility used for the service are obtained from available Environmental Product Declarations (EPDs). In the absence of EPDs, a simplified estimate is made according to the VERUM method based on the proportion of materials in the product. The case studies compare the carbon footprint of a service by omitting and including employee mobility and service-related management.ResultsThe analysed case studies show an impact share between 32 and 69% for employee mobility and between 10 and 26% for service-related management activities in an integrated carbon footprint of services. The emissions caused by employee mobility and service-related management therefore have a dimension that should not be neglected.ConclusionsFrom these findings, the necessity is derived to include the emissions from the mobility of operational staff and service-related management in future PCRs for services in order to improve the comparability of services. Optimisation efforts of companies must also start at these points of the service organisation.
Manipulating Spin Polarization of Defected Co3O4 for Highly Efficient Electrocatalysis
Authors: Li Yue , Wang Tianzuo , Asim Muhammad , Pan Lun , Zhang Rongrong , Huang Zhen-Feng , Chen Zhichao , Shi Chengxiang , Zhang Xiangwen , Zou Ji-Jun 
Published: June 2022

AbstractElectrocatalytic water splitting is limited by kinetics-sluggish oxygen evolution, in which the activity of catalysts depends on their electronic structure. However, the influence of electron spin polarization on catalytic activity is ambiguous. Herein, we successfully regulate the spin polarization of Co3O4 catalysts by tuning the concentration of cobalt defects from 0.8 to 14.5%. X-ray absorption spectroscopy spectra and density functional theory calculations confirm that the spin polarization of Co3O4 is positively correlated with the concentration of cobalt defects. Importantly, the enhanced spin polarization can increase hydroxyl group absorption to significantly decrease the Gibbs free energy change value of the OER rate-determining step and regulate the spin polarization of oxygen species through a spin electron-exchange process to easily produce triplet-state O2, which can obviously increase electrocatalytic OER activity. In specific, Co3O4-50 with 14.5% cobalt defects exhibits the highest spin polarization and shows the best normalized OER activity. This work provides an important strategy to increase the water splitting activity of electrocatalysts via the rational regulation of electron spin polarization.
Early warning of coal dynamic disaster by precursor of AE and EMR "quiet period"
Authors: He Shengquan , Qin Mengli , Qiu Liming , Song Dazhao , Zhang Xiufeng 
Published: June 2022

AbstractEfficient and accurate monitoring and early warning of coal dynamic disaster and other disasters can provide guarantee for the efficient operation of mine transportation system. However, the traditional threshold early warning method often fails to warning some accidents. To address above issues, a new early warning method was proposed based on "quiet period" phenomenon of AE and EMR during fracture. It is found that, a "quiet period" of AE and EMR was present before the load reaches the peak stress, which could be used as one of the precursors to warn the imminent failure of coal and rock specimens. MS and AE signals increased abnormally followed by the phenomenon of "quiet period" before the occurrence of coal dynamic disaster on site, and the decrease of MS events in the "quiet period" is about 57%–88% compared with that in previous abnormal increase stage. During the damage evolution of coal and rock, "quiet period" phenomenon usually occurred at 85%–90% of the peak stress, where the slope of damage parameter curve is almost zero. The "quiet period" of the AE-EMR signals and the low change rate of damage parameter before failure provide a theoretical foundation for the coal dynamic disaster warning based on the "quiet period" precursor found in MS-AE-EMR monitoring system. These findings will help reduce the number of under-reported events and improve early warning accuracy.
Metal Peptide Conjugates in Cell and Tissue Imaging and Biosensing
Authors: Gkika Karmel S. , Cullinane David , Keyes Tia E. 
Published: June 2022

AbstractMetal complex luminophores have seen dramatic expansion in application as imaging probes over the past decade. This has been enabled by growing understanding of methods to promote their cell permeation and intracellular targeting. Amongst the successful approaches that have been applied in this regard is peptide-facilitated delivery. Cell-permeating or signal peptides can be readily conjugated to metal complex luminophores and have shown excellent response in carrying such cargo through the cell membrane. In this article, we describe the rationale behind applying metal complexes as probes and sensors in cell imaging and outline the advantages to be gained by applying peptides as the carrier for complex luminophores. We describe some of the progress that has been made in applying peptides in metal complex peptide-driven conjugates as a strategy for cell permeation and targeting of transition metal luminophores. Finally, we provide key examples of their application and outline areas for future progress.
„Kriseninternes Lernen“ und „krisenübergreifendes Lernen“ in der deutschen Kommunalverwaltung
Authors: Bauer Michael W. , Otto Jana , Schomaker Rahel M. 
Published: June 2022

ZusammenfassungKrisen testen die Leistungsfähigkeit von Verwaltungen unter Realbedingungen. Vor diesem Hintergrund analysiert der vorliegende Beitrag Reaktion der deutschen Kommunalverwaltung auf die Fluchtmigration zwischen 2015 und 2017 und auf die erste Welle der COVID-19-Pandemie in 2020. Mit Blick auf die Debatte zum organisationalen Lernen in Ausnahmesituationen liegt der Schwerpunkt der Analyse auf der Rolle administrativer Netzwerke sowie der Lernfähigkeit von öffentlichen Behörden während sowie zwischen Krisensituationen. Die Auswertung zweier Umfragen unter Mitarbeitern der deutschen Kommunalverwaltung zeigt erstens, dass die Qualität der verwaltungsinternen und der zivilgesellschaftlichen Vernetzung von zentraler Bedeutung für administrative Krisenperformanz sind. Zweitens korrespondiert Leistungsfähigkeit in Krisen mit der Bereitschaft sowie mit der Fähigkeit, Lehren aus früheren Krisen zu ziehen.