bluuebunny/crossref_metadata_2025_split huggingface dataset:
ON OPTIMIZATION OF THE NORMS OF THE CRIMINAL CODE OF THE RUSSIAN FEDERATION ON LIABILITY FOR VIOLATION OF STATE SECRETS
Authors: Савинский А.В. 
Published: July 2022

Статья посвящена проблеме повышения эффективности уголовно-правовой защиты государствен-ной тайны, в частности оптимизации норм Уголовного кодекса Российской Федерации (далее УК РФ), предусматривающих ответственность за разглашение государственной тайны (статья 283) и ут-рату ее материальных носителей (статья 284). Утрата материальных носителей гостайны наносит вред безопасности государства лишь в случае ознакомления с ними посторонних лиц, т. е. утрата яв-ляется разновидностью разглашения. Преступление по статье 284 УК РФ в качестве составообра-зующего признака объективной стороны предусматривает наступление тяжких последствий, что ха-рактерно и для квалифицированного разглашения гостайны (ч. 2 статьи 283 УК РФ). Данные уго-ловной статистики убедительно свидетельствуют, что уголовная ответственность по статье 284 на-ступает крайне редко. Указанные обстоятельства служат предпосылкой для объединения названных статей УК РФ в единую статью. Автор представляет редакцию такой «объединенной» статьи.
The article is devoted to the problem of increasing the effectiveness of criminal law protection of state se-crets, in particular, optimizing the norms of the Criminal Code of the Russian Federation (hereinafter re-ferred to as the Criminal Code of the Russian Federation), which provide for liability for divulging state secrets (article 283) and the loss of its material carriers (Article 284). The loss of material carriers of state secrets harms the security of the state only if unauthorized persons become familiar with them, i.e. loss is a form of disclosure. The crime provided for by Article 284 of the Criminal Code of the Russian Federa-tion as a constituent feature of the objective side provides for the onset of grave consequences, which is also typical for the qualified disclosure of state secrets (part 2 of Article 283 of the Criminal Code of the Russian Federation). Criminal statistics provide convincing evidence that criminal liability under Article 284 is extremely rare. These circumstances serve as a prerequisite for combining the above articles of the Criminal Code of the Russian Federation into a single article. The author represents a new draft of such a “combined” article.
The correlation between knowledge and nurse compliance in the use of personal protective equipment level 2
Authors: Mardiansyah Mardiansyah , Febtrina Rizka , Yanti Sri , Kharisna Dendy 
Published: July 2022

Background: Personal Protective Equipment (PPE) is divided into 3 levels, the use of which is adjusted to the location of health services due to the COVID-19 pandemic. The second level of PPE is intended for health workers who work in patient care rooms. One of the causes of high cases of nurses contracting viral infections is the lack of knowledge and compliance in using PPE.
Purpose: The aim of this study was to find out the correlation between knowledge and nurse compliance in the use of PPE level 2.
Methods: This study was a quantitative research with correlational analytic type. The number of respondents was 62 nurses. Collecting data using a knowledge (8 qoestions) and compliance (10 questions) questionnaire of nurses in the use of PPE level 2. The analysis used was univariate and bivariate analysis with the Pearson Product Moment test with level of significance at the alpha = 0.05.
Results: The results of the univariate analysis of knowledge obtained a mean value of 6.16 with a standard deviation of 1.04 and nurses’ compliance obtained a mean value of 34.67 with a standard deviation of 3.56. The results of the study concluded that there was no significant correlation between knowledge and nurse compliance in the use of PPE level 2 in Petala Bumi Hospital, Riau Province with p = 0.513 and r = 0.085.
Conclusions: This study suggests that nurses increase knowledge and compliance with the use of level 2 PPE in providing nursing services by attending training, seminars and workshops on preventing disease transmission, especially during the COVID-19 pandemic.
Antibiogram and Detection of Metallo-β-Lactamase Producing Escherichia coli Isolated From Cow Dung in Owo Metropolis
Authors: Adeluwoye-Ajayi Olayemi Amos , Bello Adedoyin Ayowole , Thomas Folarin Moses , Omoniyi Oluwasegun Victor 
Published: July 2022

This study was carried out to determine the antibiotic susceptibility profile and the production of metallo-β-lactamase (MBL) by Escherichia coli isolated from cow dung in Owo metropolis. The isolation of Escherichia coli was done using MacConkey agar and Eosin Methylene Blue Agar and was conventionally characterized. Antimicrobial susceptibility test of the isolates were by disc diffusion method against ceftazidime (30 µg), cefuroxime (30 µg), gentamicin (10 µg), cefixime (5 µg), ofloxacin (5 µg), augmentin (30 µg), nitrofurantoin (300 µg) and ciprofloxacin (5 µg). Detection of MBL producing isolates was by imipenem-EDTA combined disc test. The isolates showed highest resistance to augmentin (97.8%) and least resistance to nitrofurantoin (20.0%). Out of the 45 Escherichia coli isolated from cow dung, 8 (17.8%) produced MBL and were all multidrug resistant. The production of MBL and the high prevalence of antibiotic resistance observed among the Escherichia coli in this study infer that cow dung does not only serve as a reservoir for MBL-producers but also as source for the growth and dissemination of clinically significant antibiotic resistant species. Hence, the use of antibiotics as growth enhancers in cow production should be discouraged to help prevent the spread of antibiotic resistant bacteria and thus, preserve the efficacy of available antibiotics.
Integrated Effect of Organic and Inorganic Manuring on Crop Yield and Soil Nutrient Balance in the On-going Century-old Permanent Manurial Experiment
Authors: Sabeena M. S. , Sridevi G. , Jayanthi D. , Balachandar D. , Dheebakaran Ga. 
Published: July 2022

Aim: The present study reports the results of continuous application of different rates of N, P and K and organic manure to a Maize-Sunflower cropping system on the changes in soil available nutrients status after harvest of 172th crop of maize.
Materials and Methods: We studied the long-term effect of organic and inorganic manuring on crop yield and soil nutrient management under Maize–Sunflower cropping system in 112 years old Permanent Manurial Experiment Field. Significant build-up in soil fertility in terms of alkaline KMnO4-N, Olsen-P, NH4OAc-K, K2Cr2O7–C and CaCl2-S as well as DTPA-Fe, Mn, Cu, Zn were assessed under eight treatments consist of Unfertilized Control, NP, NP, NPK (Chemical Fertilizer Alone), FYM (N Equivalent Basis), FYM (Every Year), Poultry Manure and NPK+FYM.
ResultS and Discussion: Recorded data from 2008 shows that continuous application as 100%NPK+FYM @12.5 t ha-1 achieved highest grain yield (hybrid maize CO 6), soil organic carbon, available nitrogen, available potassium, available sulphur and micronutrients content. Highest P recorded in poultry manure on nitrogen equivalent basis than INM irrespective of the crops. Inorganic fertilizer application alone resulted in a pH of >8.0, whereas fertilizer and manure application as well as manure application alone resulted in a pH of < 8.0 in soil. The increase in available S in INM, NPK alone might be due to single super phosphate (SSP) and FYM which contained about 12 and 0.74 % of S, respectively. Thus, considering soil-quality conservation and crop yield, 112 years of study indicated that combined application of NPK and organic manure is a better nutrient-management option in this irrigated maize sunflower cropping system.
Conclusion: These results conclude that for better crop yield and soil quality, integrated usage of organic and inorganic nutrient should be advocated in the Maize-Sunflower cropping system under Alfisol.
Fusion Assessment in Stand Alone Oblique lumbar interbody fusion in Adult Degenerative Lumbar Scoliosis: A Prospective Study
Authors: Elkazaz Mohamed K. , Abdelmonem Ahmed M. , Abou-Madawi Ali , Alshatoury Hassan A. , AlQazaz Mohamed Yousef , Salem Khalid 
Published: July 2022

Background data: The degenerative lumbar diseases form a burden on both the patients and the society. The development of the degenerative process is highly linked to the aging process as discussed by Kirkandly Willis where the degenerative spine passes through 3 phases of process that results in the degenerative diseases. The management of the degenerative spine deformities varies and depends on various factors. Traditional surgical management involves instrumentation, decompression and fusion processes. Oblique Lumbar interbody fusion ‘OLIF’ is a novel technique when used alone as in stand-alone OLIF ‘SA-OLIF’ it could achieve degenerative deformity correction along with neural decompression, however, the final aim of SA OLIF where solid fusion is required still is under evaluation and literature lacks the essential data for this approach. This study aims to assess the fusion of the SA-OLIF in the management of degenerative lumbar scoliosis.
Study Design: A Prospective clinical case study.
Objective: To assess the fusion rates in patients suffering from degenerative lumbar scoliosis ADS after SA-OLIF.
Patients and Methods: Patients with ADS following a specific inclusion criterion underwent SA OLIF. Pre-, and Post-operative clinical data; back and leg pain ‘VAS score’ and ODI, radiological data; for fusion assessment. Intra-operative data: operative time, amount of blood loss, complications ‘intra-operative or post-operative’ and hospital stay were all analyzed and compared statistically.
Results: A total of 28 patients and 30 levels were operated by SA OLIF, with mean age 50.54±6.05 included 14 males and 14 females. The mean operative time/min, blood loss/ml and hospital stay/day was 91.29±14.23, 195.54±42.299 and 2.78±0.875 respectively. The mean of Back Pain ‘VAS’, The mean of Leg Pain ’VAS’ and ODI changed from pre-operatively 7.36±0.98, 6.36±0.911and 68.615±8.72 to 4.07±1.01, 2.07±0.9 and 20.23±4.7 in 1-year respectively. In this study we had 92.9% fusion rates after 1-year. Operative complications occurred in 3 cases with segmental artery injury. Post-operative complications were 1 cage dislodgment immediately post-operative and 2 cases of cage subsidence after 1-year.
Conclusion: SA OLIF can result in high rates of fusion. There are multiple factors that determine the rate of fusion such as the quality of the vertebrae and endplate preservation during the preparation procedure.
Kariya Pod-husks: A Novel Biocatalyst in Biodiesel Production
Authors: Ogundahunsi O. E. , Ogunsina B. S. , Aransiola E. F. 
Published: July 2022

Diverse challenges faced with the use of homogeneous catalysts in biodiesel production coupled with the interest in converting waste resources to useful products in solving occurring climatic and environmental challenges around the world have triggered research into the use of various heterogeneous catalysts. In this study, the catalytic properties of kariya pod-husks were investigated to examine their suitability in biodiesel production. Kariya pod-husks were ash and calcined at 600oC for 4 h. In the morphological structure examination, the scanning electron image of calcined kariya pod-husks shows that it has a more compact microstructure with a cluster of big crystals but irregular pores which is an attribute of high catalytic potentials. The elemental composition of the calcined kariya pod-husks reveals that it contains a higher percentage weight of calcium (42%) and potassium (31%) which makes it a more suitable catalyst for biodiesel production. The developed catalyst was further used in the production of kariya biodiesel. A biodiesel yield of 94% was obtained. This study shows that calcined kariya pod-husks could catalyze biodiesel production. It also helps in proving suitable biocatalyst to solve the challenges associated with the separation of catalyst from the product stream which consequently aids in the creation of continuous chemical processes.
Sulfur‐Catalyzed Oxidative Condensation of Aryl Alkyl Ketones with o‐Phenylenediamines: Access to Quinoxalines
Authors: Nguyen Le Anh , Nguyen Thi Thu Tram , Ngo Quoc Anh , Nguyen Thanh Binh 
Published: July 2022

AbstractWhile elemental sulfur has been largely used as oxidant or sulfurating agent, its role as a catalyst has not been developed. We report here its catalytic activity in the oxidative condensation of o‐phenylenediamines with acetophenones in DMSO to provide quinoxalines. The method was also extended to α‐tetralones, propiophenones (R=Me) as well as higher homologues (R=Et, n‐Pr) in place of acetophenones, leading to a wide range of naphthoquinoxalines and 3‐substituted 2‐arylquinoxalines.magnified image
Asymmetric Gold(I)‐Catalyzed Tandem Hydroarylation–Nazarov Cyclization: Enantioselective Access to Cyclopentenones
Authors: Solas Marta , Suárez‐Pantiga Samuel , Sanz Roberto 
Published: July 2022

AbstractThe asymmetric synthesis of cyclopentachromenones from gold‐catalyzed reaction of readily available skipped alkenynones is described. This cascade reaction involves an initial anti‐Michael hydroarylation of the ynone moiety to form a gold‐functionalized dialkenylketone intermediate, followed by a Nazarov cyclization that proceeds in an unprecedented enantioselective manner. Excellent enantiomeric ratios and chemical yields are obtained under mild reaction conditions.
Stable Two‐Legged Parent Piano‐Stool and Mixed Diborabenzene‐E4 (E=P, As) Sandwich Complexes of Group 8
Authors: Dietz Maximilian , Arrowsmith Merle , Reichl Stephan , Lugo‐Fuentes Leonardo I. , Jiménez‐Halla J. Oscar C. , Scheer Manfred , Braunschweig Holger 
Published: July 2022

AbstractA cyclic alkyl(amino)carbene‐stabilized 1,4‐diborabenzene (DBB) ligand enables the isolation of 18‐electron two‐legged parent piano‐stool Fe0 and Ru0 complexes, [(η6‐DBB)M(CO)2], the ruthenium complex being the first of its kind to be structurally characterized. [(η6‐DBB)Fe(CO)2] reacts with E4 (E=P, As) to yield mixed DBB‐cyclo‐E4 sandwich complexes with planar E42− ligands. Computational analyses confirm the strong electron‐donating capacity of the DBB ligand and show that the E4 ligand is bound by four equivalent Fe−P σ bonds.
Motion planning for a high order Dubins vehicle
Authors: Liu Yuanyuan , Zhang Wei 
Published: July 2022

AbstractIn this paper, we focus on the motion planning problem (MPP) of a generalized Dubins vehicle (GDV) with higher order dynamics, aiming at mitigating the drawbacks caused by the lack of smoothness of the Dubins curves. In the two‐dimensional case, the MPP is converted, by exploiting the Pontryagin maximum principle, into the problem of solving a set of algebraic equations (AEs). The solution of the set of AEs, which can also be applied to the MPP of chained‐form and flat systems, is found by systematically using the concept of elementary symmetric polynomial. Furthermore, in extending our results to the three‐dimensional case, the explicit expression of a new class of space curves is obtained using the Frenet frame. Simulation results show the superiority of the curves generated by the GDV over that generated by the conventional Dubins vehicle.
Schadenspriorisierungsanalyse bei Eisenbahnbrücken – Priorisierung von Brückenschäden bei der Deutschen Bahn nach dem Prinzip der FMEA
Authors: Bartels Jan‐Hauke , Naraniecki Hubert , Marx Steffen 
Published: July 2022

AbstractFür die Zuverlässigkeit von Brücken ist die Instandhaltung essenziell. Ein wichtiger Bestandteil dieses Prozesses ist die Bauwerksinspektion, in der der Zustand der betrachteten Brücke bewertet wird. Diese Inspektionen folgen aktuell festgelegten Fristen. Aufgrund der begrenzten personellen und finanziellen Kapazitäten für die Instandsetzung von Brückenschäden stellt sich die Frage, welche dieser Schäden prioritär zu behandeln sind. Ein Lösungsansatz ist die Ausfalleffektanalyse (engl. Failure Mode and Effects Analysis, FMEA). Mit der Adaption der Methode soll eine, im Vergleich zu heute, objektivere Priorisierung der Schäden vorgenommen werden. Die Herausforderung besteht darin, die FMEA an die Inspektionsdaten von Brücken zu koppeln. Hierfür wurde eine hohe Zahl an Schadensdaten von Eisenbahnbrücken ausgewertet, die von der DB Netz AG bereitgestellt wurden. Die adaptierte Methode wird als Schadenspriorisierungsanalyse (SPA) bezeichnet, an die Schadenssystematik der DB Netz AG angepasst und schließlich an Schadensdaten von Spannbeton‐ und Stahlbrückenüberbauten validiert. Für die Bewertung wurden die drei Parameter Bedeutung, Wirksamkeit und Kosten definiert. Das Produkt der drei Parameter gibt Auskunft über die Kritikalität eines Brückenschadens. Trotz ihrer Bauformabhängigkeit ermöglicht die SPA eine objektivere Schadensbewertung. Somit kann sie bei der fundierten Instandhaltungsplanung von Brücken helfen und die Entscheidung der zu priorisierenden Schäden erleichtern.
Evaluation of isoflavone extraction options at commercial scale
Authors: Chea John D. , Lehr Austin L. , Stanzione Joseph F. , Yenkie Kirti M. 
Published: July 2022

AbstractResource sustainability concerns keep increasing owing to the continuous use of natural materials without reclamation. Efforts are ongoing to find sustainable feedstocks for naturally derived products with competitive economics and properties. However, there is no established methodology for commercializing the extraction of chemicals from renewable sources. This work examined soybeans as a potential bio‐based feedstock to generate isoflavones at a commercial scale. The isoflavone content in soybeans has proven beneficial in the nutraceuticals industry for its anti‐inflammatory and cancer‐inhibition properties and in the materials sector owing to their inherent chemical functionality and thermal resistance. Currently, isoflavone extraction is only optimized at lab scale. Thus, we present a superstructure‐based framework to screen isoflavone extraction methods and assess their viability at a commercial scale. This allows the simultaneous comparison of alternative technologies using mixed‐integer nonlinear programming optimization to determine the most economical pathway. Internal material recovery greatly enhances the viability at a commercial scale by reducing the annual operating cost and environmental footprint. Therefore, this work presents a powerful tool for systematically comparing extraction pathways and assessing their commercial feasibility. The successful implementation of commercial‐scale extraction of isoflavone has tremendous potential for generating additional revenue for US soy farmers. Isoflavones can produce bio‐based polymers and composites and are used in products such as dietary supplements, cosmetics and nutraceuticals. Similar works can be applied to extract other natural materials from renewable feedstocks and increase the production of bio‐based products. © 2022 Society of Chemical Industry and John Wiley & Sons, Ltd.
Reassessing acetyl‐CoA supply and NADPH availability for mevalonate biosynthesis from glycerol in Escherichia coli
Authors: Wang Yan , Zhou Shenting , Li Runyi , Liu Qian , Shao Xixi , Zhu Liyan , Kang Min‐Kyoung , Wei Gongyuan , Kim Seon‐Won , Wang Chonglong 
Published: July 2022

AbstractMevalonate is an important platform compound for the biosynthesis of isoprenoids. It can be synthesized from acetyl‐CoA in the presence of nicotinamide adenine dinucleotide phosphate (NADPH) by the introduced mvaES operon in Escherichia coli. The influences of E. coli hosts, acetyl‐CoA supply, and NADPH availability were assessed and engineered to improve the production titer and yield of mevalonate from glycerol. As a result, E. coli DH5α was found to be the best host with high specific capability and titer of mevalonate from glycerol. Through the engineering of phosphoketolase‐phosphotransacetylase (xPK‐PTA) bypass and NADPH availability, a final titer of 7.21 g/L with a specific capability of 1.36 g/g dry cell weight was gained in flask culture. Our work could offer new information to metabolically engineer the mevalonate pathway for the efficient production of isoprenoids.
Integration of UPLC–QE–MS/MS and network pharmacology to investigate the active components and action mechanisms of tea cake extract for treating cough
Authors: Lin Cheng , Liu Zhiping , Chen Jia , Wang Xuanxuan , Zhang Rui , Wu Longhuo , Li Linfu 
Published: July 2022

AbstractThe active components and mechanisms of tea cake extract (TCE) were investigated for treating cough. The components of TCE were tentatively identified by ultrahigh‐performance liquid chromatography coupled with Q‐Exactive MS/MS (UPLC–QE–MS/MS), whose targets were obtained from the Swiss Target Prediction database and the Traditional Chinese Medicine Systems Pharmacology database and analysis platform. Cough‐related targets were retrieved from the Gene Cards and Online Mendelian Inheritance in Man database. After the intersection targets had been obtained, enrichment analysis of Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways were determined, and the protein–protein interaction network and active compound‐intersection target–KEGG pathway network were constructed. Core active compounds and their targets were validated with molecular docking. A total of 78 compounds were identified from TCE, including 24 flavonoids, 17 phenolic acids, 10 alkaloids, seven organic acids, five triterpenes, five amino acids, five coumarins, three carbohydrates, one anthraquinone and one other. A total of 347 intersection targets were obtained. The top five GO terms with the most significant P‐values were responses to oxygen‐containing compounds and organic substances, chemical and cellular responses to chemical stimulus, and regulation of biological quality. The top five KEGG pathways with the most significant P‐values were: the PI3K‐Akt signaling pathway, lipids and atherosclerosis, human cytomegalovirus infection, fluid shear stress and atherosclerosis, and proteoglycans in cancer. The top five core active compounds were quercetin, genistein, luteolin, kaempferol and emodin. The top five core targets were protein kinase B (Akt1), prostaglandin‐endoperoxide synthase 2 (PTGS2), mitogen‐activated protein kinase 1/3 (MAPK1/3) and phosphoinositide‐3‐kinase regulatory subunit 1 (PIK3R1). The top five core active compounds could stably bind to their targets with LibDockScores higher than 100. Tea cake extract plays the antitussive role via multiple components and targets. Core targets (AKT1, MAPK1, MAPK3 and PIK3R1) and core components (quercetin, genistein, luteolin and kaempferol) involved in the PI3K‐Akt signaling pathway are worth more attention in subsequent validation experiments.