bluuebunny/crossref_metadata_2025_split huggingface dataset:
NIA START-UP CHALLENGE AND ACCELERATOR: EMPOWERING AGING RESEARCHERS FOR ENTREPRENEURIAL SUCCESS
Authors: Toliver Joy 
Published: January 2025

Abstract
As an effort to support the development of aging researchers transitioning into entrepreneurship, the National Institute on Aging designed and launched its Start-Up Challenge and Accelerator. Through a five-month accelerator program, participants learn how to translate their research-driven solutions into market-ready products that promote healthy aging. Participants receive personalized mentorship, entrepreneurial training, networking opportunities, and a chance to win NIA funding. With cohorts in 2022 and 2023, the Startup Challenge and Accelerator supported the development of 40 transitioning entrepreneurs that are developing innovations to enhance the health and/or care of older adults and awarded cash prizes to eleven. Since the completion of the first cohort, graduates of the program have hit a multitude of milestones including, but not limited to, a company exit, raising venture capital financing, launching health system pilots, securing key strategic partners, and winning national pitch competitions. By attending this panel, you will learn more about the program, how to apply, and how past participants have leveraged the program to fuel their entrepreneurial growth and establish a path to success.
NIA FUNDED OBATALA SCIENCES: DRIVING DIVERSITY IN RESEARCH ENTREPRENEURSHIP AND ADVANCING REGENERATIVE MEDICINE
Authors: Frazier Trivia 
Published: January 2025

Abstract
Obatala Sciences, Inc. developed the first human-derived hydrogel for 2D and 3D cell culture which can be applied in various organ-on-a-chip models. The New Orleans-based Obatala Sciences fat-on-a-chip platform and supporting products offer researchers a new, more accurate way of modeling human fat tissue in-vitro. Obatala Sciences was spun out of the NIH/NIA funded LaCell LLC in 2017. To build on their prior SBIR and seed funding, Obatala Sciences raised $3 million in Series A investments in 2022. Obatala’s scientific and thought leadership are committed to promoting diversity to advance the study and prevention of diseases in the fields of obesity, diabetes, tissue engineering and regenerative medicine. In 2022, Obatala also received NIA funding to create an entrepreneurship in biotechnology training program in partnership with universities in Southeast Louisiana. The newly developed program is leveraging the diverse background and training of the diverse regional student population to give students greater insight into biotech and entrepreneurial career paths.
IMPACT OF GENDER FOR ELDER MISTREATMENT WITHIN DEMENTIA FAMILY CAREGIVING
Authors: Pickering Carolyn , Wood Leila 
Published: January 2025

Abstract
Gender plays a significant role in interpersonal violence throughout life, particularly through gender-based violence or violence driven by gender-based power dynamics. However, understanding the role of gender in elder mistreatment within dementia family caregiving is more complex due to the various layers affected by gender. For instance, societal gender norms often lead to women being primary caregivers, and trends in dementia mean women are more likely to be care recipients. Gender influences access to caregiver resources, such as financial support, and impacts outcomes like caregiver depression. This symposium aims to explore the diverse ways gender influences elder mistreatment in family caregiving contexts. The first paper investigates how the gender of the caregiver influences the likelihood of engaging in various subtypes of elder mistreatment. The second paper delves into how polysubstance use affects the risk of different types of elder mistreatment, and how this risk varies based on caregiver gender. The third paper examines perceived reciprocity as a protective factor for elder mistreatment subtypes and explores whether it plays a stronger role based on caregiver gender. The last paper utilizes a gerofeminist lens to examine the intersection of gender and physical disability in the risk of being victimized by various subtypes of elder mistreatment.
GENDER DIFFERENCES IN TYPES OF AGGRESSION USED AMONG DEMENTIA FAMILY CAREGIVERS
Authors: Browning Wesley , Yildiz Mustafa , Pickering Carolyn 
Published: January 2025

Abstract
Investigations of family violence across the lifespan have revealed that men more often rely on physically aggressive tactics towards while women often rely on forms of psychological aggression. Physical aggression use also declines with age. We aimed to replicate, within a sample of dementia family caregivers, findings on gender, age and aggression from family violence research. We hypothesized that male family caregivers engage more often in physically aggressive behaviors towards their relative with dementia, while women engage more often in psychological aggression. Caregivers (n=453) self-reported frequency of neglect, psychological aggression, and physical aggression in the past 6-months at enrollment, 6-month and 12-month follow up. We utilized linear regression to investigate age and gender differences in abuse and neglect at baseline. We employed mixed models for repeated measures to investigate whether men engaged more often in abusive and neglectful behaviors across the three waves. Men (n=57) engaged more often in neglect and physical aggression than women (p’s&lt;.05) at baseline. Caregivers who were older women engaged more often in neglect, while younger men engaged more often in physical abuse (p’s&lt;.05). Based on our mixed model, men engaged more often in neglectful behaviors (B=-3.71, p=.001), physically aggressive behaviors (B=-1.55, p&lt;.001) and overall total behaviors (B=-5.61, p=.001) than women across the three waves. Findings replicate those from prior studies examining family violence across the lifespan. Special attention should be paid to male caregivers in research and clinical practice as men are uniquely at risk for abusive and neglectful behaviors.
OUTCOMES OF ASSISTED LIVING ACCREDITATION IN NORTH CAROLINA
Authors: Zimmerman Sheryl , Efird-Green Lea , Sloane Philip , Reed David , Tian Yuke , Davis Scott , Preisser John 
Published: January 2025

Abstract
Accreditation is a widely used health care review process to determine if an organization meets a defined standard of quality. The opportunity for accreditation recently moved into the field of assisted living (AL); today, seven states have statutes and regulations allowing third party accreditation to satisfy full or partial compliance with state licensure or certification. Data indicate that compliance with accreditation standards may result in improved care, but it has not been evaluated in AL. In 2021, the state of North Carolina funded an AL accreditation pilot program to evaluate whether accreditation improves or maintains quality. Communities were randomly allocated to a control or accreditation arm and are being followed for two years to evaluate care and outcomes in five areas (workforce, resident outcomes, care coordination and transitions, medication management, person-centered care). Of the 146 communities originally enrolled that provided data, most are for-profit (96%) and part of a chain (73%); 44% pf residents have dementia, 25% have mental illness, and 53% receive state financial assistance. Preliminary results in the first two quarters (Q) found an overall increase in advance care planning discussions (53% in Q1 and 63% in Q2), and a decrease in medication administrations with one or more errors (1.2% in Q1 and 0.6% in Q2). This session will present results comparing communities in the control arm, accreditation arm, and those that successfully achieved accreditation, with findings having wide-ranging implications for the future of AL accreditation and regulation in North Carolina, and implications across the country.
INDIVIDUAL, FAMILY, AND COMMUNITY FACTORS THAT SHAPE COGNITIVE AGING: AN ECOLOGICAL SYSTEMS APPROACH
Authors: Hamm Jeremy , Mogle Jacqueline 
Published: January 2025

Abstract
Healthy cognitive aging is shaped in part by individual and social-environmental factors that span systems delineated by social ecological models of lifespan development. This symposium addresses the role of individual- (beliefs, health behaviors), family- (relationship quality), and community-level (neighborhood quality) factors as predictors of normative and non-normative cognitive aging. Taylor et al. use individual-level data from the Midlife in the United States (MIDUS) Study to demonstrate how a composite of control beliefs, purpose in life, and social support prospectively predicts healthier 9-year trajectories of cognitive aging. Hamm et al. use individual-level MIDUS data to document how (health behavior mechanisms) and when in the lifespan (age-moderated pathways) longitudinal changes in control beliefs predict corresponding shifts in cognitive functioning. McGrath et al. investigate novel methods in measuring individual-level indices of health behavior-dependent muscle function (force stability, explosiveness) that can better predict risk of cognitive impairment. Jang et al. use data from the National Study of Daily Experiences (NSDE) to identify the influence of different types of family-level relationships on the experience of daily memory lapses and associated negative affect. Finally, Cerino et al. use NDSE data to document how better neighborhood quality at the community-level is linked to better cognitive functioning, particularly for individuals who lack control over the daily stressors they experience. This symposium thus contributes to a more comprehensive understanding of how healthier cognitive aging is shaped by modifiable beliefs, behaviors, social dynamics, and neighborhood factors that span multiple ecological systems.
EDUCATION ON COMMUNICATION WHILE WEARING FACEMASKS USEFUL DESPITE THE END OF COVID-19 EMERGENCY
Authors: Shaw Clarissa , Williams Kristine , Coleman Carissa , Nakad Lynn 
Published: January 2025

Abstract
Communication with nursing home residents by formal caregivers is complicated with the use of facemasks. Yet facemask use is necessary to limit the spread of disease during surges of communicable respiratory illnesses. The purpose of this study was to develop and pilot test a web-based educational module to promote successful communication with nursing home residents while wearing facemasks. To create CHATO-PPE, we completed a scoping review of 39 articles and interviewed 19 formal caregivers, nursing residents, and family members from four states on best practices for communication with facemasks. We integrated these results to create a 30-minute web-based module. The module includes three videos we produced with a scenario that begins as an undesirable care encounter and with our education improves with practical communication tips and then becomes a successful care encounter with the integration of person-centered communication. To evaluate our module, we recruited a convenience sample of 26 formal caregivers in nursing homes. Confidence in dementia care measured by the CODE scale increased significantly from before to after the modules (p=.009). Greater than 90% of participants agreed that they would recommend the course to others, use the training in their job, and were satisfied overall. In post-education interviews, learners stated that mask use is still prevalent in nursing homes during surges of respiratory illnesses and CHATO-PPE provides helpful and feasible tips to implement during these times while also serving as a reminder of communication best-practices that can be used regardless of facemask use.
ASSOCIATION BETWEEN PRE–HIP FRACTURE ANTIDEPRESSANT USE AND HOSPITAL LENGTH OF STAY AMONG MEDICARE BENEFICIARIES
Authors: Mehta Rhea , Falvey Jason , Chen Chixiang , Dong Yu , Shardell Michelle , Yamashita Takashi , Orwig Denise 
Published: January 2025

Abstract
Antidepressants are the first-line treatment for depression among older adults. Their use presents important sex differences and is linked to hospital length of stay (LOS), which can affect hip fracture recovery. Given the push to deprescribe these medications among older adults, exploring the effect of antidepressant use prior to hip fracture among older adults with existing depression is important. Thus, our study examined the association between pre-fracture antidepressant use and hospital LOS among hip fracture survivors, and related sex differences. The sample included 17,936 community-dwelling Medicare fee-for-service beneficiaries with depression and a hospitalization claim for hip fracture surgery between 2010 and 2017. Ordinal logistic regression was used to estimate the association between pre-fracture antidepressant use, measured 6 months prior to fracture, and hospital LOS in days, a categorical outcome variable classified into three groups (1-4, 5-8, and 8+ days) during the 30-day post-fracture period. In the covariate-adjusted model, hip fracture survivors with depression who used antidepressants pre-fracture had 6.7% higher odds of a shorter hospital LOS compared to non-users (odds ratio [OR]=1.07; 95% CI=1.01, 1.13; p=0.03). Males had longer LOS on average (mean=6.02, standard deviation [SD]=4.07) compared to females (mean=5.43, SD=3.17), but the sex-by-antidepressant use interaction was not significant (p=0.83). Treating existing depression with antidepressants was associated with shorter hospital LOS in this sample. The findings suggest a benefit of antidepressant use prior to hip fracture which may inform clinical decision-making surrounding depression management among hip fracture survivors to optimize recovery trajectories.
ASSOCIATIONS BETWEEN INCARCERATION HISTORY AND DIABETES MANAGEMENT AMONG OLDER ADULTS
Authors: Blank Sabrina , Sneed Rodlescia 
Published: January 2025

Abstract
The number of older adults with criminal justice system involvement has increased by more than 280% since 1999. Previous studies show that justice-involved older adults have rates of chronic disease similar to those of the never-incarcerated; however, no studies have evaluated differences in disease management between groups. We examined associations between history of incarceration (HOI) and diabetes management using data from the Health and Retirement Study, a population-based sample of community-dwelling older adults. HOI was assessed via self-report. We assessed diabetes management via self-report/objective health indicators, health service utilization, and health behaviors. We used logistic and linear regression to evaluate associations between HOI and diabetes management, controlling for demographic characteristics. HOI was associated with fewer dental visits (OR: 0.069; 95% CI: 0.531, 0.917) and greater odds of insulin use (OR: 1.52, 95% CI: 1.13, 2.05), tooth loss (OR: 1.94, 95% CI 1.43, 2.65), foot swelling (OR: 1.44, 95% CI: 1.08, 1.90) and hospitalization in the last 2 years, (OR: 1.47, 95% CI: 1.12, 1.92). There was no association between HOI and other measures of diabetes management. Associations between tooth loss, dental visits, and incarceration were observed among White but not Black participants. Findings suggest that HOI may be associated with poorer diabetes management practices in some domains. Future research should identify interventions that improve diabetes-relevant outcomes among justice-involved older adults.
MAXIMIZING THE SCALABILITY OF THE CHRONIC DISEASE SELF-MANAGEMENT PROGRAM AMONG OLDER ADULTS IN STATE PRISONS
Authors: Sneed Rodlescia 
Published: January 2025

Abstract
Incarcerated older adults have high rates of chronic disease; however, there is limited chronic disease programming in most state prison systems. The Chronic Disease Self-Management Program (CDSMP) is an evidence-based program that has been used within state prisons on a limited basis, but there has been little research into efficient and effective strategies for scaling up the intervention within state prisons. Scale-up (i.e. deliberate efforts to increase the impact of successfully tested health innovations to benefit more people and promote sustainability) is an understudied concept with few existing empirical studies explicitly focused on the scale-up process. Assessing scalability, however, is crucial for ensuring sustainability of complex interventions within resource-poor settings. The purpose of this study was to evaluate and maximize the scalability of CDSMP among older adults in state prisons. Guided by the Scaling up Management Framework, we conducted interviews with representatives from 10 U.S. state prison systems on ways to maximize the scalability of CDSMP within state correctional settings. Participants provided information in numerous areas related to scale-up, including strategies for achieving buy-in, special situations where implementation might be especially difficult, potential funding strategies, and ideal partners for scale-up efforts. As the prison population continues to age, the burden of chronic disease within correctional systems will continue to increase, which contributes to skyrocketing correctional costs. Understanding how to expand evidence-based chronic disease programs within correctional systems is crucial for reducing disease-related morbidity and mortality among incarcerated individuals and for reducing costs.
SOCIAL INTERACTION AND DEPRESSIVE SYMPTOMS: A COMPARISON OF MID- TO LATER-LIFE SAME- AND DIFFERENT-SEX COUPLES
Authors: Mernitz Sara , Garcia Michael , Umberson Debra 
Published: January 2025

Abstract
Social interaction with family and friends plays a crucial role for individual mental health with notable gendered patterns. Yet, previous studies fall short in explaining how the frequency of social interactions change over time for women and men in same-sex and different-sex married couples and how such change may influence depressive symptoms from midlife to late adulthood. Using dyadic longitudinal data from the Health and Relationships Projects (HARP), we examine patterns of change in social interaction frequency over a 6-year period for mid-to-later life U.S. women and men in same-sex and different-sex marriages (n = 616 individuals; 320 couples) and their subsequent associations with depressive symptoms. We use mixed-effects multilevel modeling and find that the frequency of social interaction with family members decreased over a period of 6 years for same-sex couples (i.e. women married to women; men married to men), but not different-sex couples. Frequency of social interaction with friends also decreased, but only for men married to men. Decreased social interaction with family members was associated with increased depressive symptoms for women married to women, but not men married to men or different-sex couples; decreased social interaction with friends was associated with increased depressive symptoms for men married to men only. Taken together, these findings illustrate how change in social interaction frequency influences mental health within marriage from mid-to-later life and underscores the importance of including same-sex couples when considering both gender differences in such linkages.
POOLING COHORTS ACROSS THE LIFE COURSE TO IDENTIFY NOVEL EARLY-LIFE DETERMINANTS OF HEALTH OUTCOMES IN LATER-LIFE
Authors: Kezios Katrina , Zimmerman Scott , Buto Peter , Glymour M Maria , Hazzouri Adina Zeki Al 
Published: January 2025

Abstract
To answer novel questions about exposure-disease effects over the entire life course, researchers are increasingly pooling data from multiple cohorts covering different life periods to construct complete life course data. If carefully constructed, these “synthetic cohorts” should enable rigorous investigation of earlier-life determinants and pathways to health in older age. Using simulations, we previously demonstrated a matching-based approach to create a synthetic cohort where individuals with exposure (“A”) information in an early-life cohort were matched to individuals with outcome (“Y”) information in a later-life cohort based on mediators and confounders of A and Y. Here, we describe results from a proof-of-concept analysis using a sample-splitting approach in the Health and Retirement Study (1994-2018). We examined the relationships between BMI in 1994 and 1) general health, 2) diabetes, and 3) systolic blood pressure in 2018 in synthetic cohorts constructed using 2008 as the matching time point. Synthetic cohort estimates were benchmarked against those in the longitudinal HRS sample observed from 1994-2018. In the proof-of-concept analyses, our approach was most successful when a later measure of the exposure and/or earlier measure of the outcome was available in both cohorts at the matching time-point. For example, for BMI1994 and general health2018, matching cohorts on BMI and general health in 2008 alone produced an estimate of -0.0386 [-0.054, -0.023] in the synthetic cohort (compared with -0.0334 [-0.040, -0.027] in the full cohort). We use these findings to guide analyses examining the relationship between other early life social and cardiovascular determinants and later-life health.
WAGE DISPARITIES IN NURSING HOMES: ORGANIZATIONAL AND MARKET FACTORS
Authors: Orewa Gregory , Ghiasi Akbar , Davlyatov Ganisher , Lord Justin , Weech-Maldonado Robert 
Published: January 2025

Abstract
Although wage differences across NHs are evident, the underlying factors contributing to these differences remain largely unexplored. The primary purpose of this study was to examine the organizational and market factors associated with nurse wages in NHs. This study used secondary datasets such as the Payroll Based Journals, Medicare cost reports. and Care Compare (2017-2022). It included all U.S. NHs certified by the Centers for Medicare and Medicaid Services (CMS). Analytic data comprised 80,244 facilities, averaging 13,374 unique NHs per year. The data was modeled using multiple linear regression with two-way fixed effects (year and state). We ran separate models for the three types of nurses employed by NHs: registered nurses (RNs), licensed practical nurses (LPNs), and certified nursing assistants (CNAs) wages. The dependent variable was the adjusted nurse wage (RNs, LPNs, and CNAs) per hour after accounting for inflation. The key variable of interest was a categorical variable that captured the intersection of ownership status and chain affiliation: for-profit-chain (FPC), for-profit independent (FPI), not-for-profit chain (NFPC), and not-for-profit independent (NFPI). Other organizational and environmental factors that may be associated with nurse wages were also included. The results suggest that compared to NFPIs, FPIs and FPCs were associated with lower nurse wages (p&lt;.01). NHs with more Medicaid residents pay lower wages, while those located in wealthier areas and with larger size pay higher wages. Our findings highlight the need to ensure equitable wage distribution across NHs, particularly by addressing the financial challenges faced by facilities located in more deprived communities.