bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incidence and Disability in Dementia in the Republic of Belarus
Authors: Голубева Т.С. , Докукина Т.В. , Короткевич Т.В. , Старцев А.И. , Шеремет Е.А. , Будько Т.О. 
Published: April 2022

Осуществлено исследование эпидемиологических данных о заболеваемости и инвалидности при деменциях в Республике Беларусь, в том числе деменции при болезни Альцгеймера и сосудистой деменции, которое позволило охарактеризовать динамику показателей заболеваемости и выхода на инвалидность при данной патологии в зависимости от пола, возраста и места проживания.
The study of the epidemiological data on the incidence and disability in dementia in Belarus was carried out, including dementia in alzheimer’s disease and vascular dementia, which let to characterize the dynamics of the incidence and disability rates in this pathology depending on gender, age, and place of residence.
First Experience of Production of Pooled Pathogen-Reduced Plasma for Transfusion
Authors: Буркитбаев Ж.К. , Абдрахманова С.А. , Бибеков Ж.Ж. , Балтабаева Т.С. , Скорикова С.В. , Кенжин А.Е. , Альменова З.Е. , Мусилимова С.Т. , Сапаргужина Д.Б. , Мадзаев С.Р. , Жибурт Е.Б. 
Published: April 2022

Определили качество пулированной патоген-редуцированной донорской плазмы. Све жезамороженную плазму (СЗП) получали из крови 48 доноров (19 женщин и 29 мужчин). Приготовили 10 пулов плазмы (9 – из 5 доз и 1 – из 3 доз). Для инактивации патогенов использовалась технология с применением амотосалена и ультрафиолета А. Пулированная патоген-редуцированная плазма содержит достаточное количество фибриногена и фактора VIII и является более стандартизованным продуктом по сравнению с образцами СЗП отдельных доноров. Пулированная патоген-редуцированная с использованием амотосалена и ультрафиолета А плазма содержит достаточное количество фибриногена и фактора VIII, а также соответствует требованиям качества в соответствии c нормативами Республики Казахстан и Совета Европы и является более стандартизованным продуктом по сравнению с образцами СЗП отдельных доноров.
The quality of the pooled pathogen-reduced donor plasma was determined. Fresh frozen plasma (FFP) was obtained from the blood of 48 donors (19 women and 29 men); 10 plasma pools were prepared (9 – from 5 units and 1 – from 3 units). The technology using amotosalen and ultraviolet A was used to inactivate pathogens. The pathogen-reduced plasma contains a sufficient amount of fibrinogen and factor VIII; and it is a more standardized product in comparison with the FFP samples of individual donors. The pathogen-reduced (using amotosalen and ultraviolet A) plasma contains a sufficient amount of fibrinogen and factor VIII. It meets the quality requirements in accordance with the standards of the Republic of Kazakhstan and the Council of Europe. It is a more standardized product in comparison with the FFP samples of individual donors.
The Influence of Lyophilization on the Coagulation Composition of Virus-Inactivated Blood Plasma
Authors: Кривов И.А. , Рагимов А.А. , Салимов Э.Л. 
Published: April 2022

В статье приведены данные исследования по изучению сохранения коагуляционного потенциала в лиофилизированной плазме, инактивированной тремя различными технологиями: амотосалена и облучением ультрафиолетом спектра А, рибофлавина + ультрафиолет спектра B, метиленового синего + видимый свет. В исследовании проводился анализ концентрации факторов свертывания крови, влияющих на внешний, внутренний и общий пути свертывания, сравнивая образцы вирусинактивированной лиофилизированной плазмы различными методами инактивации. В результате исследования существенных различий в показателях между образцами плазмы, инактивированной различными методами, не было выявлено. Следовательно, вирусинактивированная лиофилизированная плазма может служить полноценной альтернативой свежезамороженной плазме.
The article presents the research data on the conservation of coagulation potential of lyophilized plasma inactivated with three different technologies – amotosalen and ultraviolet irradiation of spectrum A, riboflavin + ultraviolet of spectrum B, methylene blue + visible light. In the study, there was analyzed the concentration of blood-coagulation factors that affect the extrinsic, intrinsic, and general coagulation pathways by comparing the samples of virus-inactivated lyophilized plasma with various inactivation methods. As a result of the study, no significant differences in the indices between the samples of plasma inactivated with various methods were detected. Therefore, virus- inactivated lyophilized plasma can serve as a full alternative to fresh frozen plasma.
Evaluation of the Risk of Development of Distant Lymphohematogenous Metastases in Patients with Radically Operated Gastric Cancer
Authors: Ревтович М.Ю. , Красько О.В. 
Published: April 2022

Введение. Оценка вероятности развития отдаленных лимфогематогенных метастазов может позволить индивидуализированно подойти к планированию адъювантного лечения, направленного на профилактику системного прогрессирования рака желудка в отдаленные сроки после радикальной операции.Цель. Повысить эффективность прогнозирования отдаленных лимфогематогенных метастазов у радикально оперированных по поводу рака желудка пациентов.Результаты. На основании анализа результатов 1065 радикально оперированных пациентов (мужчин – 640 (60,1%), женщин – 425 (39,9%); возраст пациентов от 23 до 89 лет, в среднем 63±12 лет) установлено, что высокий риск прогрессирования рака желудка с формированием перитонеальной диссеминации имеет место при метастатическом поражении регионарного лимфоколлектора любой степени (pN1 – ОР 2,9 (95% ДИ 1,6–5,1), р<0,001; pN2 – ОР 3,6 (95% ДИ 2,0–6,7), р<0,001; pN3 – ОР 5,0 (95% ДИ 2,8–8,7), р<0,001); наличии язвенно-инфильтративной формы роста первичной опухоли – ОР 2,2 (95% ДИ 1,4–3,4), р<0,001. На основании результатов многофакторного анализа (модель Файна – Грея) предложена прогностическая модель для оценки вероятности развития метахронной перитонеальной диссеминации (индекс конкордации 0,75).Вывод. Использование разработанной прогностической модели позволит дифференцированно подойти к назначению адъювантного лечения с учетом имеющейся вероятности развития отдаленных лимфогематогенных метастазов в отдаленные сроки после радикальной операции.
Introduction. Evaluation of the probabilities of development of distant lymphohematogenous metastases can help to use the individualized approach to adjuvant treatment planning directed to prevent systemic progression of gastric cancer after radical surgery.Purpose. To increase the effectiveness of prediction of distant lymphohematogenous metastases in patients with radically operated gastric cancer.Results. On the base of the outcomes of treatment of 1,065 radically operated patients (males – 640 (60.1%), females – 425 (39.9%)) of 23-89 years old (average age – 63±12), it was revealed that the high risk of gastric cancer recurrence in the form of peritoneal dissemination is associated with the presence of (1) the various-degree metastatic invasion of the regional lymph node (pN1 – RR 2.9 (95% CI 1.6–5.1), р<0.001; pN2 – RR 3.6 (95% CI 2.0–6.7), р<0,001; pN3 – RR 5.0 (95% CI 2.8–8.7),р<0,001), and (2) the ulcero-infiltrative form of primary tumor growth (RR 2.2 (95% CI 1.4–3.4), р<0,001). Competing risks were estimated by means of a multivariate analysis based on the Fine- Gray model, and the prognostic model was developed to predict the probabilities of development of metachronous peritoneal dissemination (concordance index – 0.75).Conclusion. The use of the proposed prognostic model lets to differentiate patient-specific adjuvant therapies, taking into account the probabilities of late occurrence of lymphohematogenous metastases after radical surgery.
Clinical Effectiveness of Minimally Invasive Diagnostics of Cellular Rejection after Kidney Transplantation
Authors: Носик А.В. , Коротков С.В. , Смольникова В.В. , Гриневич В.Ю. , Дмитриева М.В. , Пикиреня И.И. , Калачик О.В. , Кривенко С.И. , Щерба А.Е. , Руммо О.О. 
Published: April 2022

Цель. Продемонстрировать клиническую эффективность применения разработанного алгоритма диагностики клеточного отторжения почечного аллографта в отдаленные сроки после трансплантации. Материалы и методы. Проведено проспективное интервенционное исследование, включившее 10 реципиентов трансплантата почки. В основную группу исследования включены 5 пациентов с отторжением почечного аллографта, диагностированным разработанным алгоритмом. Контрольную группу составили 5 пациентов с неиммунной дисфункцией трансплантата. В основной группе исследования начата специфическая терапия отторжения по результатам предлагаемого теста. Всем участникам произведена биопсия трансплантата почки. Результаты и обсуждение. Применение специфической терапии по результатам предлагаемого алгоритма привело к снижению сывороточного креатинина (140 127 111 мкмоль/л) и росту скорости клубочковой фильтрации (43,5 46,5 58,6 мл/мин). Сравнение результатов предлагаемого метода с результатами гистологического исследования продемонстрировало хорошие диагностические характеристики. Чувствительность и специфичность были равны 100,0 (95 ДИ 45,97100,0) для обеих характеристик. Выводы. Применение специфической терапии позднего клеточного отторжения по результатам предлагаемого алгоритма является эффективным. Предлагаемый алгоритм обладает хорошими диагностическими характеристиками в сравнении с гистологическим исследованием.
Purpose. To demonstrate clinical effectiveness of use of the developed algorithm for diagnostics of cell rejection of renal allograft in the long term after transplantation. Materials and methods. We conducted a prospective interventional comparative study, which included 10 patients. The experimental study group included 5 patients with rejection, which was diagnosed with the developed algorithm. The control group consisted of 5 patients with non- immune transplant dysfunction. In the experimental study group, specic rejection therapy was initiated, according to the results of the proposed test. All the participants underwent a kidney transplant biopsy. Results and discussion. The use of specic therapy based on the results of the proposed algorithm led to decrease of serum creatinine (140 127 111 mol/l) and increase of GRF (43.5 46.5 58.6 ml / min). The comparison of the results of the proposed method with the results of the histological study demonstrated good diagnostic characteristics. Sensitivity and specicity were 100.0 (95 CI 45.97100.0) for both characteristics. Conclusions. The use of specic therapy for treatment of late cellular rejection based on the results of the proposed algorithm is effective. The proposed algorithm has good diagnostic characteristics in comparison with histological examination
Anemia in the Elderly. A Review
Authors: Куликов И.А. , Демихов В.Г. 
Published: April 2022

Цель обзора. Показать, что анемия пожилых не является неизбежным следствием старения. Несмотря на высокую распространенность анемии у пожилых пациентов, этому явлению не уделяется необходимого внимания.Основные положения. Анемия пожилых представляет значительную проблему для здравоохранения. Это распространенное состояние у пожилых людей, которое ухудшает течение практически всех заболеваний, а также увеличивает частоту смерти от всех причин. Диагностика причин анемий в пожилом возрасте бывает затруднена из-за полиэтиологичности анемии в пожилом возрасте. Наиболее частыми этиологическими факторами анемий у пожилых являются абсолютный дефицит железа, хроническое воспаление, хроническая болезнь почек, дефицит витамина В12. Большуюгруппу составляют анемии неясной этиологии.Заключение. Анемию пожилых следует рассматривать именно как заболевание и лечить, а не списывать ее как «неизбежное следствие старения». Диагностические алгоритмы для пациентов молодого возраста недостаточно надежны для пожилых пациентов.
Purpose. To show that anemia is harmful to elderly patients and is not an inevitable consequence of aging. Despite the high prevalence of anemia in elderly patients, this phenomenon is not given the necessary attention by clinicians.Background. Anemia in elderly is a significant public health problem. It is a common condition in the elderly that worsens almost all diseases and increases the incidence of all-cause death. Diagnosis of the causes of anemia in the elderly is difficult because of polyetiology of the phenomenon. The most common etiological factor of anemia in the elderly is an absolute iron deficiency, chronic inflammation, chronic kidney disease,vitamin B12 deficiency. A large group is anemia of unknown etiology.Conclusion. Anemia in elderly should be considered as a disease to be treated, as opposedto being accepted as an "inevitable consequence of aging". Today’s diagnostic and treated algorithms for young and adult patients are not sufficiently reliable for elderly ones.
PET/CT in Richter Syndrome. Review and Own Clinical Cases
Authors: Алексеев С.А. , Троян В.Н. , Рукавицын О.А. 
Published: April 2022

В статье представлены обзор и анализ современной литературы по вопросам применения позитронно-эмиссионной томографии, совмещенной с компьютерной томографией, с использованием 18F-ФДГ у пациентов, страдающих хроническим лимфолейкозом / лимфомой из малых лимфоцитов, у которых диагностирована трансформация заболевания в более агрессивные лимфомы, такие как диффузная В-крупноклеточная лимфома или лимфома Ходжкина.Описанная трансформация носит название синдрома Рихтера.Актуальность обзора литературы определяется имеющимся и возрастающим интересом специалистов в области рентгенологии, радиологии и онкогематологии к оценке, выявлению и дифференциальному диагнозу данного состояния с применением ПЭТ/КТ с 18F-ФДГ.
The article is devoted to the review and analysis of the current literature on the use of positron emission tomography, combined with computed tomography, using 18F-FDG in patients with chronic lymphocytic leukemia / small lymphocyte lymphoma, who have been diagnosed with the transformation of the disease into more aggressive lymphomas, such as diffuse B-large cell lymphoma or Hodgkin’s lymphoma.The described transformation is called Richter’s syndrome.The relevance of the literature review is determined by the existing growing interest of specialists in the field of radiology, radiology and oncohematology in the assessment, detection and differential diagnosis of this condition using PET/CT with 18F-FDG.
Sound Archives and Musical Representations of Modern India: The Case of the Felix van Lamsweerde Collection (1963-2005)
Authors: Ajotikar Rasika 
Published: April 2022

This essay presents a critical social history of the context in which the Felix van Lamsweerde Collection came together. Felix van Lamsweerde (b. 1934), a Dutch collector, cultural anthropologist and impresario, extensively recorded Indian expressive cultures in the Netherlands and India between 1963 and 2005. This collection was digitised and catalogued between 2017 and 2020 at Georg-August-Universität Göttingen and the Berliner Phonogramm-Archiv in Germany as part of a German Research Foundation (DFG) project. It includes a wide range of first-hand and commercial audio/video recordings of music, dance and theatre genres from across India along with accompanying notes, photographs, and a vast collection of books, magazines and journals. Van Lamsweerde’s journey into studying musics of India and the collection itself points to how India’s cultural politics evolved in the immediate decades following its independence from the British in 1947. Whilst historicising the colonial, oriental and nationalist legacies of music collection in India, this essay examines the Van Lamsweerde Collection and archival projects at large through a source critical approach. It attempts to demonstrate the ways in which caste, class, gender and racialisation processes and the sound archive shaped one another in the formation of transnational cultural representations of India. Drawing on discussions in ethnomusicology, social theory and archival studies, this essay offers an interpretation of how musical knowledge and a homogenous construct of Indian culture has taken shape in Western European and American academe.
Mixtapes from Heaven: The Global Duke Ellington Fandom and the Music they Preserved
Authors: Feustle Maristella 
Published: April 2022

The Rhodes S. Baker, Jr. Collection of rare and unissued sound recordings at the University of North Texas Music Library demonstrates that, in archival settings, the incidental content that is often deleted from commercial releases is actually “a feature, not a bug,” so to speak. This article elaborates on two reasons for the desirability and necessity of such content: First, it often provides the context necessary to make sense of a given recording, determining a date and release status, especially for recordings that are not well labeled. It also provides lasting evidence of the human activity underlying every aspect of the performance, capture, distribution, and preservation of a recording.
The Rhodes S. Baker, Jr. Collection’s unissued recordings of Duke Ellington and other major jazz artists, packed onto reel-to-reel tapes like the “mixtapes” of decades later, have obvious intrinsic value. Still, preserving and acknowledging the human activity that compiled them adds value: doing so provides a window into the depth and intensity of the “fandom” (or community of fans) that thrived for Ellington even in his sixties, along with the multifaceted efforts to preserve his live performances.
Ellington and his music created an international fan community, and their story augments his own. This article describes historically significant content from the Rhodes S. Baker, Jr. Collection, digitized in early 2016, in the context of the social participation of Baker and other fans and collectors, including the prominent Swedish collector and discographer Benny Aasland. The preservation and description of the collection demonstrates a complementary relationship between archival practice and musicologist Christopher Small’s concept of musicking. Insights from Pauline Oliveros and John Cage further inform an approach to musicking inclusive of incidental sounds and other artifacts of recorded live performance which might otherwise be dismissed as “noise,” but are essential to the full context of the captured performance.
Potensi Alga Halymenia durvillei Sebagai Sumber Antioksidan Alami
Authors: Moniung Prisilia , Singkoh Marina , Butarbutar Regina 
Published: April 2022

Red algae have the ability to produce secondary metabolites which are bioactive compounds. The content of secondary metabolites from red algae can be determined by an approach method that can provide information on the presence of secondary metabolites. The purpose of this study was to identify bioactive compounds, as well as to analyze the natural antioxidant activity of H. durvillei algae. Extracts were made by maceration method using 96% ethanol. Antioxidant activity test using DPPH method. Algae extract H. durvillei contains compounds of alkaloids, tannins, saponins and phenols which have antioxidant activity that can counteract the formation of free radicals. The results of antioxidant tests conducted using UV-Vis spectrophotometry on the ethanolic extract of H. durvillei algae showed an IC50 value of 101.22 ppm. Keywords: Red Algae (H. durvillei); Bioactive Compounds; Natural Antioxidants ABSTRAKAlga merah memiliki kemampuan untuk memproduksi metabolit sekunder yang bersifat sebagai senyawa bioaktif. Kandungan senyawa metabolit sekunder dari alga merah dapat diketahui dengan suatu metode pendekatan yang dapat memberikan informasi adanya senyawa metabolit sekunder. Tujuan penelitian ini untuk mengidentifikasi senyawa bioaktif, serta menganalisis aktivitas antioksidan alami yang terdapat pada alga H. durvillei. Pembuatan ekstrak dilakukan dengan metode maserasi menggunakan etanol 96%. Uji aktivitas antioksidan menggunakan metode DPPH. Ekstrak Alga H. durvillei memiliki kandungan senyawa alkaloid, tanin, saponin dan fenol yang memiliki aktivitas antioksidan yang dapat menangkal terbentuknya radikal bebas.Hasil uji antioksidan yang dilakukan menggunakan spektrofotometri UV-Vis pada ekstrak etanol alga H. durvillei menunjukkan nilai IC50 sebesar 101.22 ppm. Kata Kunci: Alga Merah (H. durvillei); Senyawa Bioaktif; Antioksidan Alami
PROGRAM PEMBERIAN MAKANAN TAMBAHAN DALAM UPAYA MENURUNKAN ANGKA STUNTING DI KOTA CIMAHI
Authors: Kirana Cintantya Andhita Dara , Reviandani Oktarizka , Damayanti Alfina 
Published: April 2022

Poverty is one of the main causes of hunger. In 2020 based on the GHI or Global Hunger Index report, Indonesia scored 19.1. BPS noted that malnutrition rates in Indonesia reached 30,000 or one out of every 10,000 residents. One in three babies in Indonesia is diagnosed with stunting where the number of stunted toddlers in Indonesia is still at 30.7%. Some efforts that can be made to overcome hunger levels and reduce stunting rates include improving food intake, parenting, and paying attention to sanitation and providing clean water to the community. One of the programs that is being optimized by the government to improve the level of public health and nutrition by running an Additional Feeding Program (PMT). Cimahi city is a city with stunting rates in toddlers reaching 11.01% and stunting in toddlers reaching 9.87%. Government Regulation No. 42 of 2013 regulates the National Movement for The Acceleration of Nutrition Improvement, Improvement of Community Nutrition through The Additional Feeding Program (PMT) is one of the government programs implemented to reduce stunting rates and improve community nutrition in Cimahi City.
Impact on on-resistance of p-n junction diodes by using heavily Ge-doped GaN substrate
Authors: Ohta Hiroshi , Asai Naomi , Mochizuki Kazuhiro , Horikiri Fumimasa , Narita Yoshinobu , Mishima Tomoyoshi 
Published: April 2022

Abstract
The characteristics of p-n junction diodes on heavily Ge-doped substrates were compared with those on conventional Si-doped substrates. A large decrease in on-resistance was observed which greatly exceeded the component due to the lower resistance of the Ge-doped substrate. This result implied an occurrence of a strong conductivity modulation by the heavily doped substrate. Current-density dependence on the anode-electrode diameter could be minimized by the use of the substrate. No significant difference was observed in the breakdown voltage even when the doping concentration in the substrate was increased. It has been clarified that the heavily Ge-doped GaN substrate is essential for low on-resistance and large size GaN power devices.
263 nm wavelength UV-C LED on face-to-face annealed sputter-deposited AlN with low screw- and mixed-type dislocation densities
Authors: Uesugi Kenjiro , Kuboya Shigeyuki , Shojiki Kanako , Xiao Shiyu , Nakamura Takao , Kubo Masataka , Miyake Hideto 
Published: April 2022

Abstract
Regarding deep-ultraviolet optical device applications, face-to-face annealed sputter-deposited AlN (FFA Sp-AlN) is a promising alternative to the conventional metalorganic vapor phase epitaxy (MOVPE)-prepared AlN templates on sapphire substrates. However, FFA Sp-AlN tends to exhibit AlGaN growth-related hillock generation and surface morphology deterioration. In this study, we optimized the sputter-deposition conditions for AlN and MOVPE growth conditions for AlGaN to respectively reduce hillock density and size. After confirming AlGaN surface-flattening, we fabricated 263 nm wavelength UV-C LEDs on the FFA Sp-AlN and achieved maximum external quantum efficiencies of approximately 4.9% and 8.0% without and with silicone encapsulation, respectively.