bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flares detected in ALMA single-dish images of the Sun
Authors: Skokić I. , Benz A. O. , Brajša R. , Sudar D. , Matković F. , Bárta M. 
Published: November 2022

Context. The millimeter and submillimeter radiation of solar flares is poorly understood. Without spatial resolution, millimeter emission cannot be easily compared to flare emission in other wavelengths. Though the Atacama Large Millimeter-submillimeter Array (ALMA) offers sufficient resolution for the first time, ALMA cannot be used on demand to observe when a flare occurs, and when used as an interferometer, its field of view is smaller than an active region.
Aims. We used readily available large-scale single-dish ALMA observations of solar millimeter flares and compared them to well-known features observed in other wavelengths. The properties of these other flare emissions, correlating in space and time, could then be used to interpret the millimeter brightenings and vice versa. The aim is to obtain reliable associations limited by the time and space resolution of single-dish observations.
Methods. Ordinary interferometric ALMA observations require single-dish images of the full Sun for calibration. We collected such observations at 3 mm and 1 mm and searched for millimeter brightenings during times listed in a flare catalog.
Results. All of the flares left a signature in millimeter waves. We found five events with nine or more images that could be used for comparison in time and space. The millimeter brightenings are associated with a variety of flare features in cool (Hα, 304 Å), intermediate (171 Å), and hot (94 Å) lines. In several cases, the millimeter brightening peaked at the footpoint of a hot flare loop. In other cases the peak of the millimeter brightening coincided with the top or footpoint of an active Hα filament. We also found correlations with post-flare loops and the tops of a hot loop. In some images, the millimeter radiation peaked at locations where no feature in the selected lines was found.
Conclusions. The wide field of view provided by the single-dish ALMA observations allowed for a complete overview of the flare activity in millimeter waves for the first time. The associated phenomena often changed in type and location during the flare. The variety of phenomena detected in these millimeter observations may explain the sometimes bewildering behavior of millimeter flare emissions previously observed without spatial resolution.
A first glimpse at the line-of-sight structure of the Milky Way’s nuclear stellar disc
Authors: Nogueras-Lara F. 
Published: November 2022

Context. The nuclear stellar disc (NSD) is a dense stellar structure at the centre of our Galaxy. Given its proximity, it constitutes a unique laboratory to understand other galactic nuclei. Nevertheless, the high crowding and extinction hamper its study, and even its morphology and kinematics are not yet totally clear.
Aims. In this work we use NSD red clump stars, whose intrinsic properties are well known, to trace the kinematics of the NSD and to compute the distance and extinction towards the edges of the NSD.
Methods. We used publicly available proper motion and photometric catalogues of the NSD to distinguish red clump stars by using a colour-magnitude diagram. We then applied a Gaussian mixture model to obtain the proper motion distribution, and computed the extinction and distance towards stars with different kinematics.
Results. We obtained that the proper motion distributions contain NSD stars rotating eastwards and westwards, plus some contamination from Galactic bulge/bar stars, in agreement with previous work. We computed the distance and extinction towards the eastward- and westward-moving stars and concluded that the latter are ∼300 pc beyond, indicating a similar structure along and across the line of sight, and consistent with an axisymmetric structure of the NSD. Moreover, we found that the extinction within the NSD is relatively low and accounts for less than 10% of the total extinction of the stars belonging to the farthest edge of the NSD.
TheGaia-ESO Survey: Probing the lithium abundances in old metal-rich dwarf stars in the solar vicinity
Authors: Dantas M. L. L. , Guiglion G. , Smiljanic R. , Romano D. , Magrini L. , Bensby T. , Chiappini C. , Franciosini E. , Nepal S. , Tautvaišienė G. , Gilmore G. , Randich S. , Lanzafame A. C. , Heiter U. , Morbidelli L. , Prisinzano L. , Zaggia S. 
Published: November 2022

Context.Lithium (Li) is a fragile element that is produced in a variety of sites but can also be very easily depleted in stellar photospheres. Radial migration has been reported to explain the decrease in the upper envelope of Li measurements observed for relatively old metal-rich dwarf stars in some surveys.Aims.We test a scenario in which radial migration could affect the Li abundance pattern of dwarf stars in the solar neighbourhood. This may confirm that the Li abundances in these stars cannot serve as a probe for the Li abundance in the interstellar medium (ISM). In other words, to probe the evolution of the Li abundance in the local ISM, it is crucial that stellar intruders be identified and removed from the adopted sample.Methods.We used the high-quality data (including Li abundances) from the sixth internal Data Release of theGaia-ESO survey. In this sample we grouped stars by similarity in chemical abundances via hierarchical clustering. Our analysis treats both measured Li abundances and upper limits.Results.The Li envelope of the previously identified radially migrated stars is well below the benchmark meteoritic value (<3.26 dex); the star with the highest detected abundance has A(Li) = 2.76 dex. This confirms the previous trends observed for old dwarf stars (median ages ∼ 8 Gyr), where Li decreases for [Fe/H] ≳ 0.Conclusions.This result is supporting evidence that the abundance of Li measured in the upper envelope of old dwarf stars should not be considered a proxy for the ISM Li. Our scenario also indicates that the stellar yields for [M/H] >0 should not be decreased, as recently proposed in the literature. Our study backs recent studies that claim that old dwarfs on the hot side of the dip are efficient probes of the ISM abundance of Li, provided atomic diffusion does not significantly lower the initial Li abundance in the atmospheres of metal-rich objects.
Psoriasis und Adipositas
Authors: Seitz Anna-Theresa , Kunz Manfred , Saalbach Anja , Kalweit Lena , Vogt Lisa , Kohlmann Johannes , Simon Jan C. 
Published: November 2022

ZusammenfassungDie Psoriasis ist eine chronisch-entzündliche Hauterkrankung. Der
Entzündungsprozess betrifft nicht nur die Haut, sondern auch weitere
Gewebe, wie Gelenke, Bänder und die Gefäße. Bei einem
Großteil aller Psoriasis-Patienten bestehen Nebenerkrankungen wie
Diabetes, Übergewicht, Fettstoffwechselstörungen und
erhöhter Blutdruck. Der genaue pathophysiologische Zusammenhang zwischen
Adipositas und Psoriasis ist nicht hinreichend geklärt. Es ist unklar,
ob Psoriasis die Entstehung von Übergewicht begünstigt oder ob
Adipositas die Entstehung einer Psoriasis durch einen chronisch
pro-inflammatorischen Zustand fördert. Neuere Daten zeigen einen
deutlichen Zusammenhang zwischen der Konzentration freier Fettsäuren und
dem Ausprägungsgrad der Psoriasis. Eine Ernährungsumstellung und
eine erhöhte körperliche Aktivität haben
grundsätzlich eine positive Wirkung auf die Schuppenflechte und
können das Ansprechen der verschiedenen Therapien erhöhen.
Ablösung der Lasersondenspitze – eine seltene Komplikation der endoluminalen Therapie
Authors: Rafi-Stenger Leyla , Stücker Markus 
Published: November 2022

Zusammenfassung
Hintergrund In der Vergangenheit bestand die chirurgische
Therapie der Stammvarikose in Crossektomie, Stripping und falls notwendig in minichirurgischer
Phlebektomie. In den letzten 10 Jahren haben endoluminale Techniken und hier speziell
Lasertechniken an Bedeutung gewonnen. Komplikationen nach endoluminalen Laserprozeduren sind
selten beschrieben.
Methode Wir berichten erstmalig in einem Fallbericht über die
intraoperative Ablösung der Lasersondenspitze bei endoluminaler Therapie einer Vena saphena
magna Stammvarikose. Ein unmittelbarer sicherer Nachweis der abgelösten Sondenspitze mittels
Duplexsonografie war aufgrund der infiltrierten TLA Lösung nicht möglich. Eine CT-Diagnostik
blieb ergebnislos.
Ergebnisse Am Tag nach der Operation ließ sich die abgelöste
Sondenspitze problemlos mittels Ultraschall nachweisen. Um eine Embolisation der abgesprengten
Glaspartikel sicher zu vermeiden, entschlossen wir uns zu einem offenen chirurgischen Vorgehen
mit Resektion der Sondenspitze und Durchführung einer korrekten Crossektomie.
Schlussfolgerung Mit zeitlicher Verzögerung (Stunden) ist eine
Ortung der abgelösten Sondenspitze mittels Ultraschall sicher möglich. Chirurgische
Intervention, aber auch passives Zuwarten, sind zu diskutieren.
Fallvorstellung: Migränerezidiv nach
Covid-19-Infektion
Authors: Schmittdiel Marieluise 
Published: November 2022

ZusammenfassungDurch eine Covid-19-Infektion wird eine chronische, über 40 Jahre
bestehende Migräne, die zuvor mit Pulsatilla gut unter Kontrolle
gebracht werden konnte, reaktiviert und spricht nicht mehr auf die bisherige,
gut wirkende Arznei an. Auf den ersten Blick leidet die Patientin unter den
gleichen Migränebeschwerden. Im Zuge der erneuten Fallaufnahme zeigt
sich jedoch ein kleiner Unterschied – eine zusätzliche neue
Kopfschmerzqualität. Die Fallanalyse, die mit dem Symptomenlexikon (SL)
durchgeführt wurde, zeigt deutlich, dass Pulsatilla diese neue
Symptomatik nicht mehr abdeckt, sondern dass eine neue Arznei angezeigt ist, mit
der das Migränerezidiv erfolgreich therapiert werden kann.
Effect Produced by a Cyclooctyne Derivative on Both Infarct Area and Left Ventricular Pressure via Calcium Channel Activation
Authors: Lauro Figueroa-Valverde , Marcela Rosas-Nexticapa , Maria López-Ramos , Francisco Díaz-Cedillo , Magdalena Alvarez-Ramirez , Virginia Mateu-Armad Maria , Montserrat Melgarejo-Gutierrez 
Published: November 2022

AbstractBackground There are reports which indicate that some cyclooctyne derivatives may exert changes in cardiovascular system; however, its molecular mechanism is not very clear.Objective The aim of this study was to evaluate the biological activity of four cyclooctyne derivatives (compounds 1 to 4) produced on infarct area and left ventricular pressure.Methods Biological activity produced by cyclooctyne derivatives on infarct area was determinate using an ischemia/reperfusion injury model. In addition, to characterize the molecular mechanism of this effect, the following strategies were carried out as follows; i) biological activity produced by cyclooctyne derivative (compound 4) on either perfusion pressure or left ventricular pressure was evaluated using an isolated rat heart; ii) theoretical interaction of cyclooctyne derivative with calcium channel (1t0j protein surface) using a docking model.Results The results showed that cyclooctyne derivative (compound 4) decrease infarct area of in a dose-dependent manner compared with compound 1 to 3. Besides, this cyclooctyne derivative increase both perfusion pressure and left ventricular pressure which was inhibited by nifedipine. Other theoretical data suggests that cyclooctyne derivative could interact with some aminoacid residues (Met83, Ile85, Ser86, Leu108, Glu114) involved in 1t0j protein surface.Conclusions All these data indicate that cyclooctyne derivative increase left ventricular pressure via calcium channel activation and this phenomenon could be translated as a decrease of infarct area.
The Addition of Dydrogesterone after Frozen Embryo Transfer in Hormonal Substituted Cycles with Low Progesterone Levels
Authors: Metello Jose , Tomas Claudia , Ferreira Pedro , Santos-Ribeiro Samuel 
Published: November 2022

Abstract
Objective To determine whether a rescue strategy using dydrogesterone (DYD) could improve the outcomes of frozen embryo transfer cycles (FET) with low progesterone (P4) levels on the day of a blastocyst transfer.
Methods Retrospective cohort study including FET cycles performed between July 2019 and October 2020 following an artificial endometrial preparation cycle using estradiol valerate and micronized vaginal P4 (400 mg twice daily). Whenever the serum P4 value was below 10 ng/mL on the morning of the planned transfer, DYD 10 mg three times a day was added as supplementation. The primary endpoint was ongoing pregnancy beyond 10 weeks. The sample was subdivided into two groups according to serum P4 on the day of FET: low (< 10 ng/mL, with DYD supplementation) or normal (above 10 ng/mL). We performed linear or logistic generalized estimating equations (GEE), as appropriate.
Results We analyzed 304 FET cycles from 241 couples, 11.8% (n = 36) of which had serum P4 below 10 ng/mL on the FET day. Baseline clinical data of patients was comparable between the study groups.Overall, 191 cycles (62.8%) had a biochemical pregnancy, of which 131 (44,1%) were ongoing pregnancies, with a 29,8% miscarriage rate. We found no statistically significant differences in the hCG positive (63 vs 64%) or ongoing pregnancy rates (50 vs 43,3%) between those FETs with low or normal serum P4 values, even after multivariable logistic regression modelling.
Conclusion Our results indicate that DYD 10 mg three times a day administered in women who perform FET with P4 serum levels < 10 ng/mL, allows this group to have pregnancy rates beyond 12 weeks at least as good as those with serum levels above 10 ng/mL.
Legal Pregnancy Interruption due to Sexual Violence in a Public Hospital in the South of Brazil
Authors: Trapani Vitoria Finger , Feuerschuette Otto Henrique May , Júnior Alberto Trapani 
Published: November 2022

Abstract
Objective To analyze the cases of all women who attend to a service of legal termination of pregnancy in cases of sexual violence in a public reference hospital and to identify the factors related to its execution.
Methods Cross-sectional observational study with information from medical records from January 2014 to December 2020. A total of 178 cases were included, with an evaluation of the data referring to the women who attended due to sexual violence, characteristics of sexual violence, hospital care, techniques used, and complications. The analysis was presented in relative and absolute frequencies, medians, means, and standard deviation. Factors related to the completion of the procedure were assessed using binary logistic regression.
Results Termination of pregnancy was performed in 83.2% of the cases; in 75.7% of the cases, the technique used was the association of transvaginal misoprostol and intrauterine manual aspiration. There were no deaths, and the rate of complications was 1.4%. Gestational age at the time the patient's sought assistance was the determining factor for the protocol not being completed. Pregnancies up to 12 weeks were associated with a lower chance of the interruption not occurring (odds ratio [OR]: 0.41; 95% confidence interval [CI]: 0.12–0.88), while cases with gestational age > 20 weeks were associated with a greater chance of the interruption not happening (OR: 29.93; 95%CI: 3.91–271.50).
Conclusion The service studied was effective, with gestational age being the significant factor for resolution.
Pregestational Diabetes and Congenital Heart Defects
Authors: Maduro Catarina , Castro Luís Ferreira de , Moleiro Maria Lúcia , Guedes-Martins Luís 
Published: November 2022

AbstractStudies have consistently shown a significant increase in the risk of congenital heart defects in the offspring of diabetic mothers compared with those of nondiabetic pregnancies. Evidence points that all types of pregestational diabetes have the capacity of generating cardiac malformations in a more accentuated manner than in gestational diabetes, and there seems to be an increased risk for all congenital heart defects phenotypes in the presence of maternal diabetes. Currently, the application of some therapies is under study in an attempt to reduce the risks inherent to diabetic pregnancies; however, it has not yet been possible to fully prove their effectiveness. The present review aims to better understand the mechanisms that govern the association between pregestational diabetes and congenital heart defects and how maternal diabetes interferes with fetal cardiac development, as there is still a long way to go in the investigation of this complex process.
Nutritional Status of Iodine in a Group of Pregnant Women from the State of Minas Gerais Correlated with Neonatal Thyroid Function
Authors: Scherr Natália Campos Gonçalves , Nogueira Anelise Impelizieri , Rajão Kamilla Maria Araújo Brandão , Leite Henrique Vitor 
Published: November 2022

Abstract
Objective To evaluate the iodine sufficiency of pregnant women assisted in a University Hospital of Minas Gerais, and to correlate the urinary concentrations of maternal iodine with the fetal thyroid hormone levels at birth.
Methods Urinary iodine concentrations from 30 pregnant women with a singleton pregnancy and gestational age lower than 20 weeks were analyzed. Occasional samples of the mothers' urine were collected for the urinary iodine concentration dosage, and these were correlated with the newborns' thyroid-stimulating hormone (TSH) levels.
Results The median iodine urinary concentration of this study's pregnant women population was 216.73 mcg/l, which is proper for the group, following the World Health Organization (WHO). No cases of neonatal hypothyroidism were reported in the study, which corroborates the iodine sufficiency in this population sample.
Conclusion This study shows that despite the increased demand for iodine from pregnant women and the Brazilian Health Regulatory Agency (ANVISA) recommendation of 2013 for reduction of salt iodization levels, the population of pregnant women attended in the prenatal ambulatory of normal risk from the Federal University of Minas Gerais is considered sufficient in iodine. As a higher sample is necessary for the confirmation of these findings, it is too early to recommend the universal supplementation of iodine for Brazilian pregnant women, and more studies must be carried out, considering that iodine supplementation for pregnant women in an area of iodine sufficiency is associated to the risks of the fetus's excessive exposure to iodine.
Efficacy of Hormonal and Nonhormonal Approaches to Vaginal Atrophy and Sexual Dysfunctions in Postmenopausal Women: A Systematic Review
Authors: Sarmento Ayane Cristine Alves , Costa Ana Paula Ferreira , Lírio Juliana , Eleutério Jr José , Baptista Pedro Vieira , Gonçalves Ana Katherine 
Published: November 2022

AbstractObjective To evaluate the efficacy of the hormonal and nonhormonal approaches to symptoms of sexual dysfunction and vaginal atrophy in postmenopausal women.Data Sources We conducted a search on the PubMed, Embase, Scopus, Web of Science, SciELO, the Cochrane Central Register of Controlled Trials (CENTRAL), and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases, as well as on clinical trial databases. We analyzed studies published between 1996 and May 30, 2020. No language restrictions were applied.Selection of Studies We selected randomized clinical trials that evaluated the treatment of sexual dysfunction in postmenopausal women.Data Collection Three authors (ACAS, APFC, and JL) reviewed each article based on its title and abstract. Relevant data were subsequently taken from the full-text article. Any discrepancies during the review were resolved by consensus between all the listed authors.Data Synthesis A total of 55 studies were included in the systematic review. The approaches tested to treat sexual dysfunction were as follows: lubricants and moisturizers (18 studies); phytoestrogens (14 studies); dehydroepiandrosterone (DHEA; 8 studies); ospemifene (5 studies); vaginal testosterone (4 studies); pelvic ﬂoor muscle exercises (2 studies); oxytocin (2 studies); vaginal CO2 laser (2 studies); lidocaine (1 study); and vitamin E vaginal suppository (1 study).Conclusion We identified literature that lacks coherence in terms of the proposed treatments and selected outcome measures. Despite the great diversity in treatment modalities and outcome measures, the present systematic review can shed light on potential targets for the treatment, which is deemed necessary for sexual dysfunction, assuming that most randomized trials were evaluated with a low risk of bias according to the Cochrane Collaboration risk of bias tool. The present review is registered with the International Prospective Register of Systematic Reviews (PROSPERO; CRD42018100488).
Investigation of dynamics of laser-produced carbon plasma during the laser irradiation using collective Thomson scattering
Authors: Pan Yiming , Tomita Kentaro , Yamagata Yukihiko , Sunahara Atsushi , Nishihara Katsunobu 
Published: November 2022

Abstract
Plasma temperature, density, and flow velocity are the critical physical properties of laser produced plasma (LPP) to reveal the ablation dynamics, energy transport, and hydrodynamic evolution. In the time window during and just after laser irradiation, experimental data are very scarce so that many theoretical models remain untested. Here we report a clear evolution history of LPP expansion dynamics within 0–14 ns after the laser peak and in a region very close to the target (0.13–0.6 mm). A table-top Nd:YAG laser (intensity 6 × 109 W cm−2, pulse 7 ns) was used to generate the LPP from a planar graphite target, whose width was arranged to be smaller than the laser spot diameter to produce a one-dimensional planar expansion plasma near the target. The electron density (

n
e

), temperature (

T
e

), and drift velocity (

V
d

) in the LPPs were measured using the ion feature of collective Thomson scattering, providing a space- and time-resolved 2D profile of the LPP. The experimental observations made it possible for the expansion dynamics to be compared directly with the LPP expansion models. The results suggest that during the laser pulse, the LPP is approximately isothermal and expands predominantly one-dimensionally in the target normal direction, in which the LPP drift velocity is found to increase linearly with distance. The linear extrapolation of the velocity indicates that the LPP has a considerable velocity at the initial target surface; this velocity is approximately the speed of sound derived from the observed

T
e

. The experimental results were found to be in moderate agreement with the 1D self-similar isothermal expansion model. The ratio of the internal to kinetic energy in the observed area was ∼0.6, as predicted by the isothermal expansion model. The experimental findings were compared with the results of the 2D hybrid code STAR, and good agreement was obtained.
Tuning defect-related optical bands by channeling implants in semiconductors
Authors: Azarov Alexander , Galeckas Augustinas , Ling Francis Chi-Chung , Kuznetsov Andrej 
Published: November 2022

Abstract
Ion implantation is an excellent method to introduce defects into semiconductors, extending their functionalities in a controllable way. Herein, we investigated an option to use crystallographically aligned implants as an additional route to control the balance between optically active defects, selecting ZnO as a test material. The optical data were correlated with the structural analysis confirming the formation of different dominating crystalline defects in samples implanted along and off [0001] direction. Specifically, we demonstrated that different proportions in the contents of the extended and point defects in the initial as-implanted states of these samples, lead to prominent variations in the defect-related luminescence upon annealing. As such, we conclude that channeling implants may have an added value in the functionalization of defects in semiconductors, e.g. to tune specific spectral contents in the defect-related emission bands.