bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effects of androgen deprivation on working memory and quality of life in prostate cancer patients: The roles of hypothalamic connectivity
Authors: Chaudhary Shefali , Zhornitsky Simon , Roy Alicia , Summers Christine , Ahles Tim , Li Chiang‐Shan R. , Chao Herta H. 
Published: March 2022

AbstractBackgroundAndrogen deprivation therapy (ADT) has been associated with adverse effects on the brain. ADT alters testosterone levels via its action on the hypothalamus‐pituitary‐gonadal axis and may influence hypothalamic functions. Given the wide regional connectivity of the hypothalamus and its role in regulating cognition and behavior, we assessed the effects of ADT on hypothalamic resting state functional connectivity (rsFC) and their cognitive and clinical correlates.MethodsIn a prospective observational study, 22 men with nonmetastatic prostate cancer receiving ADT and 28 patients not receiving ADT (controls), matched in age, years of education, and Montreal Cognitive Assessment score, participated in N‐back task and quality of life (QoL) assessments and brain imaging at baseline and at 6 months. Imaging data were processed with published routines and the results of a group by time flexible factorial analysis were evaluated at a corrected threshold.ResultsADT and control groups did not differ in N‐back performance or QoL across time points. Relative to controls, patients receiving ADT showed significantly higher hypothalamus‐right mid‐cingulate cortex (MCC) and precentral gyrus (PCG) rsFC during follow‐up versus baseline. Further, the changes in MCC and PCG rsFC were correlated positively with the change in QoL score and 0‐back correct response rate, respectively, in patients with undergoing ADT.ConclusionSix‐month ADT affects hypothalamic functional connectivity with brain regions critical to cognitive motor and affective functions. Elevated hypothalamic MCC and PCG connectivity likely serve to functionally compensate for the effects of ADT and sustain attention and overall QoL. The longer‐term effects of ADT remain to be investigated.
Factors influencing social and emotional well‐being among women who sleep with women: Minority stress and compartmentalization
Authors: McIntosh Tera , Koury Abel J. , Reindl Diana , Lewis Rhiannon 
Published: March 2022

AbstractAs recent as 2019, individuals residing within the United States were not protected from employment termination on the basis of their sexual orientation. It is unsurprising, then, that a large percentage of non‐heterosexual individuals remain ‘closeted’ about their sexual identity both at home and work, which takes a psychological and physical toll. The purpose of this study was to document perceptions, feelings, and experiences among women who have sex with women in regard to social and emotional well‐being. Thirty‐seven women between the ages of 20 and 64 participated in 6 focus groups held in three states in the United States. The purpose of these focus groups was to gather data about the experiences of living in a heteronormative world and the factors that might influence social and emotional well‐being. Responses were transcribed and thematically coded. Results offer insights into main themes that can assist community members, health professionals, and scientists to better appraise the disparities and struggles of sexual minorities who experience minority stress and have to compartmentalize in order to feel safe at home, work, and their third places. Please refer to the Supplementary Material section to find this article's Community and Social Impact Statement.
Laplacian face blending
Authors: Mazala Diego , Esperança Claudio , Marroquim Ricardo 
Published: March 2022

AbstractDesigning realistic tridimensional facial models is a challenging task, not only due to the effort and artistic abilities required but also because human visual perception is very tuned to the processing of facial features. For this reason, rather than creating face models from scratch, artists usually start from a scanned model of a real person. In this work, we present a novel method for blending human faces in order to create a new one. In a nutshell, our proposal uses Laplacian smoothing to segregate layers of details from one or more faces, which are then integrated into a base face with the help of an interactive and visual editor. In particular, our method supports blending multiple faces and multiple sub‐regions in those faces. Since our approach is intuitive and relatively easy to implement, it can be integrated into artistic pipelines aiming at designing human face models from preexisting ones.
Vasa previa: A rare obstetric complication–A case series and a literature review
Authors: Degirmenci Yaman , Steetskamp Joscha , Macchiella Doris , Hasenburg Annbalou , Hasenburg Annette 
Published: March 2022

AbstractVasa previa is a rare condition. However, since the increase in assisted reproductive technologies (ARTs), clinicians are more frequently confronted with this complication. In this study, we present five cases of vasa previa prenatally diagnosed from a tertiary referral hospital with approximately 2000 births yearly.
Fatal association of COVID‐19 and acute type A aortic dissection
Authors: Irilouzadian Rana , Salehi Omran Hossein , Alirezaei Toktam 
Published: March 2022

AbstractType A aortic dissection is a catastrophic event that requires prompt diagnosis and intervention to save the patient. It seems that type A aortic dissection in COVID‐19 patients has increased severity, and even with immediate diagnosis, it has a high mortality.
Electroreduction: A Sustainable and Less Energy‐Intensive Approach Compared to Chemical Reduction for Phosphine Oxide Recycling to Phosphine
Authors: Rajput Anubha , Soni Monika , Chakraborty Biswarup 
Published: March 2022

AbstractAlthough phosphate minerals are the only naturally occurring resources of the industrially important element phosphorus,[1,2] the industrial extraction of white phosphorous (P4) from metal phosphates relies on demineralization at high temperatures (ca. 1500 °C) in the presence of coke and it releases large amounts of CO and CO2.[3] Due to wide industrial applications of white phosphorus (P4) as a manufacturing precursor for the production of fertilizers, pesticides, fireworks, and detergents,[1] a rapid shrinking of natural reserves of this mineral is obvious and thereby demands an efficient recycling strategy. Moreover, organophosphines are versatile phosphine donor ligands in the development of transition metal catalysts for the bulk‐scale production of alkenes, functional alcohols, esters, and amines. However, the production of such industrially and commercially important organic compounds is associated with the generation of tons of phosphine oxide per year, a product whose further breakdown is highly energy demanding. This essentially amounts to the need for an economic recycling strategy. At present, lab‐ and/or industrial‐scale recycling of phosphine oxide purely relies on chemical routes using metal hydrides and/or harsh reductive conditions which lead to generation of further reagent wastes. Such harsh reaction conditions and further toxic waste generation demand the development of less energy intensive methods. For the past few years, electro‐reduction of phosphine oxides to phosphines remains a pioneering approach to bypass the energy intensive chemical routes. This review summarizes the fundamental studies on electrochemistry of phosphines and phosphine oxides in 1970–1980s and implementation of such knowledge in the development of successful electro‐deoxygenation of phosphine oxides in recent times. Research outlook and future scope of this newly developing research area have also been discussed.
Multi‐scale composite finite element modeling of three‐dimensional prestressed reinforced concrete structural members: Part I—A comprehensive framework
Authors: Díaz Guillermo 
Published: March 2022

AbstractThe goal of this work is to develop a complete theoretical framework for the numerical modeling of three‐dimensional prestressed reinforced concrete structural members, soil mixture, and their interactions. This numerical formulation is based on the construction of a new composite finite element, in order to tackle the multi‐scale problem. For this purpose, the mechanical behavior of each microstructure component material will be modeled as follows: (a) for the plain concrete (PC) and the soil mixture, an anisotropic‐damage‐elastoplastic model equipped with the strong discontinuity approach will be taken into account; (b) a polycrystal plasticity model, for the steel rebars and prestrssed tendons will be captured through a new strategy solution of discontinuous bifurcation problem, with the main objective to represent the multi‐cracking phenomenon; (c) regarding the mechanical behavior of the aggregates and rocks (skeleton—hydro mechanic problem) in the PC and soil mixture, respectively, an anisotropic‐damage‐double‐poro‐polycrystal plasticity model equipped with softening material will be considered. An advanced failure algorithm based on the marching tetrahedron and the pseudo‐termic problem will be developed. Finally, the zone that characterizes the interaction between the structural member and the soil mixture will be encrusted inside the composite finite element.
Reducing the Trap Density in MAPbI3 Based Perovskite Solar Cells via Bromide Substitution
Authors: Pegu Meenakshi , Ghaderian Abolfazl , Ahmad Shahzada , Kazim Samrana 
Published: March 2022

AbstractThe past decade has witnessed tremendous advancement in the field of halide perovskite (PSK) as a choice of material for high‐performing solar cells fabrication. Here, we investigate the impact of the halide exchange through N‐bromosuccinimide (NBS) treatment in MAPbI3 based solar cells. We observed the partial halide exchange (I− to Br−) or the filling of halide (X−) vacancy upon treatment of different NBS concentrations experimentally by spectroscopic and diffractogram studies. We noted that halide exchange impacts the crystallization and is beneficial in improving the photovoltaic performance. The optimized 0.5 % NBS treated PSC exhibited a power conversion efficiency of 17.87 % due to an increment in open‐circuit voltage (Voc) and short circuit current (Jsc). We noted improved perovskite crystal growth upon Br− substitution; eventually, it helps to lower the trap density, reducing non‐radiative recombination and renders the enhancement of long‐term stability of PSC.
Light‐Induced Fragrance Release from 2‐Oxoacetates: Impact of Compound Mixtures on the Efficiency of the Norrish Type II Photoreaction in Solution and in Encapsulation Systems
Authors: Trachsel Alain , Paret Nicolas , Berthier Damien L. , Herrmann Andreas 
Published: March 2022

AbstractUnderstanding interactions between perfumes and fragrance delivery systems is key to optimising the performance of perfumed consumer articles in practical applications, where complex compound mixtures are typically used. Possible interactions of perfume ingredients on the kinetics of the Norrish type II photofragmentation of 2‐oxoacetates, used as light‐sensitive profragrances for the controlled release of volatile perfumery aldehydes and ketones, were investigated in solution. We found that (Z)‐phenyl alkene derivatives isomerised to the correspondingE‐isomers in the presence of 2‐oxo‐2‐phenylacetates, and thus considerably decreased the rate of the targeted photofragmentation. The light‐induced fragrance release from encapsulated or non‐encapsulated 2‐oxo‐2‐phenylacetate profragrances in the presence of different amounts of perfumes showed that compounds interfering with the photoreaction should be encapsulated to only a minimum extent in core‐shell microcapsules, independent of whether the profragrance is encapsulated in the same or in a different capsule, or whether it is part of the non‐encapsulated perfume oil.
Synthesis of Crosslinked 2′‐OMe RNA Duplexes Using 2‐Amino‐6‐Vinylpurine and Their Application for Effective Inhibition of miRNA Function
Authors: Abdelhady Ahmed Mostafa , Hirano Yu , Onizuka Kazumitsu , Okamura Hidenori , Komatsu Yasuo , Nagatsugi Fumi 
Published: March 2022

AbstractCrosslinking reactions to nucleic acids are an effective way to prepare stable complexes formed by covalent bonding. We demonstrated that fully 2′‐O‐methylated (2′‐OMe) RNAs having a 2‐amino‐6‐vinylpurine (AVP) exhibited an efficient crosslinking to uracil in the target RNA. Recently, we reported the preparation of crosslinked 2′‐OMe RNA duplexes using AVP and the anti‐miRNA oligonucleotides (AMOs) containing crosslinked duplexes at the terminal positions. These AMOs exhibited efficient microRNA (miRNA) inhibition at very low concentrations. In this article, we describe the chemical synthesis of 2′‐OMe oligonucleotides containing AVP and preparation of the AMOs bearing crosslinked 2′‐OMe RNA duplexes using AVP. In addition, we describe in detail the miRNA inhibition assay using these AMOs. © 2022 Wiley Periodicals LLC.Basic Protocol 1: Synthesis of phosphoramidite of 2‐amino‐6‐vinylguanosine derivativeBasic Protocol 2: Synthesis of AVP‐2′‐OMe RNABasic Protocol 3: Evaluation of the crosslink reactivity of CFO containing AVP to the 2′‐OMe RNA and preparation of AMOs containing crosslinked duplexBasic Protocol 4: miRNA inhibition assays
Nonlinear effects of ESG on energy‐adjusted firm efficiency: Evidence from the stakeholder engagement of apple incorporated
Authors: Ren Chunya , Ting Irene Wei Kiong , Lu Wen‐Min , Kweh Qian Long 
Published: March 2022

AbstractThis study examines how the (i) overall environmental, social, and governance (OESG) performance; (ii) three individual E, S, and G (IESG) performance; and (iii) subcomponents of the three individual E, S, and G (SIESG) performance affect 29 Apple Incorporation partners' energy‐adjusted firm efficiency from a nonlinear perspective. Our truncated regression findings from 145 firm‐year observations for the period of 2016–2020 indicate that the association between OESG performance and energy‐adjusted firm efficiency is U‐shaped. However, this nonlinear U‐shape exists in the individual S and G but not E of the IESG performance. Moreover, only certain subcomponents of the SIESG performance are nonlinearly related to energy‐adjusted firm efficiency. Overall, we highlight both the costs and benefits of the ESG performance for maintaining sustainable development and stakeholder engagement. The energy‐adjusted firm efficiency estimated through the multidimensional data envelopment analysis approach is also noteworthy for policy and decision‐making purposes.
Disclosure transparency and impression management: A textual analysis of board gender diversity disclosures in Canada
Authors: Ben‐Amar Walid , Bujaki Merridee , McConomy Bruce , McIlkenny Philip 
Published: March 2022

AbstractThis article examines whether firms' board gender diversity disclosures signal transparency, reveal impression management, or both. To disentangle the two disclosure motives further, we also investigate whether the disclosure features of clarity and tone are related to new women director appointments. Based on initial gender diversity disclosures of 506 Toronto Stock Exchange (TSX) publicly traded firms, our results suggest that firms committed to enhancing board diversity provide clearer disclosures and exhibit a higher level of “optimism” to signal their confidence in the positive outcomes of diversity. In contrast, firms reluctant to enhance their diversity policies engage in impression management through obfuscation and show the most “certainty” in their diversity disclosures to indicate no change to the status quo is required. We also find that tone optimism does translate into enhanced diversity practices while certainty is negatively related to subsequent diversity performance. Taken together, our findings are consistent with the assertion that firms employ a combination of signaling and impression management strategies in their disclosures about diversity practices.
Thyroid metabolism and supplementation: A review framed in sports environment
Authors: Martínez Brito Dayamin , Botrè Francesco , Romanelli Francesco , de la Torre Xavier 
Published: March 2022

AbstractObjectivesThis paper aimed to consider those features that may suggest a link between thyroid hormones pharmacology and athletes' health based on current consumption trends in a population of athletes.MethodsMethods used were observation, description, and synthesis, mainly. Among the documents reviewed were books, scientific articles, and review articles peer‐reviewed. The review covered sources published in the period 1961 to 2021. Only references with a traceable origin were accepted (DOI numbering, ISSN, and ISBN, as well as peer‐reviewed journals). The data on the consumption of thyroid hormones derivatives were extracted from the Doping Control Forms of athlete samples received at Laboratorio Antidoping FMSI of Rome from 2017 to 2021.ResultsAn overview of the biosynthesis, pharmacology, and metabolism of thyroid hormones, including thyronamines and thyronacetic acids, was presented. Likewise, a summary is presented on the relationship between thyroid hormones and ethnic and gender differences, their physiology in sport, and the reasons why their use could be considered attractive for athletes.ConclusionToday, thyroid hormones are not listed as a prohibited substance by the World Anti‐Doping Agency. However, several requests to include levothyroxine on the prohibited list are documented. The observation that the number of athletes taking thyroid hormones is growing, particularly in sports such as cycling, triathlons, and skating, should prompt an update on this topic.
The limits of convergence in the collective behavior of competing marine taxa
Authors: Burford Benjamin P. , Williams R. Russell , Demetras Nicholas J. , Carey Nicholas , Goldbogen Jeremy , Gilly William F. , Harding Jeffrey , Denny Mark W. 
Published: March 2022

AbstractCollective behaviors in biological systems such as coordinated movements have important ecological and evolutionary consequences. While many studies examine within‐species variation in collective behavior, explicit comparisons between functionally similar species from different taxonomic groups are rare. Therefore, a fundamental question remains: how do collective behaviors compare between taxa with morphological and physiological convergence, and how might this relate to functional ecology and niche partitioning? We examined the collective motion of two ecologically similar species from unrelated clades that have competed for pelagic predatory niches for over 500 million years—California market squid, Doryteuthis opalescens (Mollusca) and Pacific sardine, Sardinops sagax (Chordata). We (1) found similarities in how groups of individuals from each species collectively aligned, measured by angular deviation, the difference between individual orientation and average group heading. We also (2) show that conspecific attraction, which we approximated using nearest neighbor distance, was greater in sardine than squid. Finally, we (3) found that individuals of each species explicitly matched the orientation of groupmates, but that these matching responses were less rapid in squid than sardine. Based on these results, we hypothesize that information sharing is a comparably important function of social grouping for both taxa. On the other hand, some capabilities, including hydrodynamically conferred energy savings and defense against predators, could stem from taxon‐specific biology.
The impact of the COVID‐19 pandemic on the economic viability of distributed photovoltaic systems in Brazil
Authors: Rediske Graciele , Lorenzoni Lauren Peres , Rigo Paula Donaduzzi , Siluk Julio Cezar Mairesse , Michels Leandro , Marchesan Tiago Bandeira 
Published: March 2022

AbstractElectricity consumption in Brazil increases significantly, making feasibility studies to diversify the Brazilian electricity mix with other renewable sources become essential. However, the electricity market continues to be primarily driven by government or regulatory incentives and economic status. With the coronavirus pandemic since the beginning of 2020, the market has been undergoing significant changes that cause uncertainty in consumer investments in grid‐connected photovoltaic systems. This article presents an economic feasibility analysis of photovoltaic system installation for the Brazilian residential sector, estimating a cash and term investment and comparing the viability of the investment before the global pandemic (December 2019) with the pandemic scenario (April 2021) for each of the 27 Brazilian capitals. The baseline scenario for economic feasibility analysis calculations considered a power system of 4 kW. The results show that the effects of the pandemic in the electricity market were positive in the feasibility of investing in grid‐connected photovoltaic systems. Also, financing the system increases the chances of profitability. The current scenario is possibly the most attractive ever experienced by potential investors. However, this favorable scenario could decline in the coming years due to climatic and governmental factors.
Revenue maximization approaches in IaaS clouds: Research challenges and opportunities
Authors: Badshah Afzal , Ghani Anwar , Daud Ali , Chronopoulos Anthony Theodore , Jalal Ateeqa 
Published: March 2022

AbstractThis study critically reviews the IaaS clouds development on revenue maximization since 2012 to answer these research queries; (i) What are the main influential factors towards revenue maximization in the cloud market? (ii) What are the main challenges and resistance towards revenue maximization in cloud computing? and (iii) What are the possible solutions and potentials to these hurdles in cloud computing? The data was analyzed and the influencing factors of revenue maximization were classified into seven distinct categories, that is, the performance of the services, service level agreement and penalties management, resources scalability, resources utilization and scheduling, customers' satisfaction, cost, and pricing management, as well as advertisement and auction. These parameters are investigated in detail and new dynamics for researchers in the field of the cloud are discovered. These studies are compared against each other for the seven distinct categories and solutions are proposed for the clouds' obstacles to revenue maximization. Furthermore, in the light of the findings and revenue maximization categories, the main limitations, challenges, true potential, and new directions towards revenue maximization are explored.
New hosts for the cycad blue butterfly, Luthrodes pandava, Horsfield (Lepidoptera: Lycaenidae) in an island ecosystem
Authors: Purti Neelam , Singh Lal Ji , Pandey Arun K. 
Published: March 2022

AbstractLuthrodes pandava Horsfield (Lepidoptera: Lycaenidae) has been reported as a pest of cycad plants in the Andaman and Nicobar Islands, India for the first time. Its impact on host species is assessed. Compared to introduced species, endemic cycads appear to be most susceptible to damage by its larvae, feeding on the plant and affecting growth. Larvae damage all above‐ground plant parts. C. dharmrajii L. J. Singh and C. pschannae R.C. Srivast. & L. J. Singh, endemic to the Andaman and Nicobar Islands, are recorded here for the first time as new host plants.