bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does product touch affect consumer attitude toward a product? Meta‐analysis of effect sizes, moderators, and mediators
Authors: Liu Wumei , Wu Feng , Awan Tahir Mumtaz 
Published: December 2022

AbstractConsumers rely on physical touch in offline shopping and vicarious touch (i.e., imagining touch) in online shopping to develop their attitudes toward a product. The subject of how touching (versus not touching) affects consumer attitudes toward a product merits studying. However, past research has drawn controversial conclusions regarding the effect of product touch on consumer attitudes. This study conducted a meta‐analysis to resolve this inconsistency and explore the reasons for this inconsistency. It quantitatively analyzed 185 effect sizes in 42 empirical studies conducted between 2003 and 2022. In general, relative to not touching, touching had a positive effect on consumers' attitudes toward a product ( = 0.242, p < 0.001), and the effect size was moderate. Furthermore, the positive touch effect was mediated by consumers' cognitive experiences relating to the product and their affective experiences relating to the product. The cognitive path (total indirect effect = 0.068, p < 0.001) being stronger than the affective path (total indirect effect = 0.067, p < 0.001). Importantly, it showed that past inconsistency regarding the touch effect could be explained by moderators including product type (utilitarian versus hedonic), participants' uncertainty avoidance, and type of touch (physical touch versus vicarious touch). This study provides new insights into the product touch literature and offers valuable implications for online and offline retailing and consumer well‐being.
Metaverse marketing: How the metaverse will shape the future of consumer research and practice
Authors: Dwivedi Yogesh K. , Hughes Laurie , Wang Yichuan , Alalwan Ali A. , Ahn Sun J. (Grace) , Balakrishnan Janarthanan , Barta Sergio , Belk Russell , Buhalis Dimitrios , Dutot Vincent , Felix Reto , Filieri Raffaele , Flavián Carlos , Gustafsson Anders , Hinsch Chris , Hollensen Svend , Jain Varsha , Kim Jooyoung , Krishen Anjala S. , Lartey Jared O. , Pandey Neeraj , Ribeiro‐Navarrete Samuel , Raman Ramakrishnan , Rauschnabel Philipp A. , Sharma Amalesh , Sigala Marianna , Veloutsou Cleopatra , Wirtz Jochen 
Published: December 2022

AbstractThe initial hype and fanfare from the Meta Platforms view of how the metaverse could be brought to life has evolved into an ongoing discussion of not only the metaverse's impact on users and organizations but also the societal and cultural implications of widespread usage. The potential of consumer interaction with brands within the metaverse has engendered significant debate within the marketing‐focused discourse on the key challenges and transformative opportunities for marketers. Drawing on insights from expert contributors, this study examines the marketing implications of the hypothetical widespread adoption of the metaverse. We identify new research directions and propose a new framework offering valuable contributions for academia, practice, and policy makers. Our future research agenda culminates in a checklist for researchers which clarifies how the metaverse can be beneficial to digital marketing and advertising, branding, services, value creation, and consumer wellbeing.
Thermochromic Photonic Crystal Microspheres with Uniform Color Display and Wide Coloration Range
Authors: Jia Zhihan , Xie Rui , Hu Yaqin , Ju Xiaojie , Wang Wei , Liu Zhuang , Chu Liangyin 
Published: December 2022

AbstractThermochromic microspheres based on poly(N‐isopropylacrylamide) attract much attention in detection and sensor due to the noticeable color response and fast response rate. However, some issues such as uneven color display and narrow coloration range still limit their practical applications. Herein, novel thermochromic microspheres with homogeneous color displays and wide thermochromic range are designed by combining the microfluidic technology with the magnetically‐induced self‐assembly technique and copolymerizing acrylamide (AM) with N‐isopropylacrylamide. The photonic crystal structure with especially even colors is fast and conveniently constructed by magnetic assembly. The addition of AM makes the microspheres more hydrophilic and thus leading to a broader coloration range. The relationship between the structural color display and both the microstructures of photonic crystals and the thermo‐responsive properties of gel matrix are elucidated. The detectable temperature of microspheres rises to as high as 60°C, and displays bright iridescent color variations from orange to blue‐violet in the heating process. Importantly, their shrinking or swelling equilibrium can be reached in 80 and 105 s. Such microspheres are successfully used to visually indicate the appropriate temperature of enzymatic reaction, and have great potential in practical applications such as visual temperature detection and efficiency monitoring of chemical reactions.
Mass spectrometry for metabolomics analysis: Applications in neonatal and cancer screening
Authors: Grooms Alexander J. , Burris Benjamin J. , Badu‐Tawiah Abraham K. 
Published: December 2022

AbstractChemical analysis by analytical instrumentation has played a major role in disease diagnosis, which is a necessary step for disease treatment. While the treatment process often targets specific organs or compounds, the diagnostic step can occur through various means, including physical or chemical examination. Chemically, the genome may be evaluated to give information about potential genetic outcomes, the transcriptome to provide information about expression actively occurring, the proteome to offer insight on functions causing metabolite expression, or the metabolome to provide a picture of both past and ongoing physiological function in the body. Mass spectrometry (MS) has been elevated among other analytical instrumentation because it can be used to evaluate all four biological machineries of the body. In addition, MS provides enhanced sensitivity, selectivity, versatility, and speed for rapid turnaround time, qualities that are important for instance in clinical procedures involving the diagnosis of a pediatric patient in intensive care or a cancer patient undergoing surgery. In this review, we provide a summary of the use of MS to evaluate biomarkers for newborn screening and cancer diagnosis. As many reviews have recently appeared focusing on MS methods and instrumentation for metabolite analysis, we sought to describe the biological basis for many metabolomic and additional omics biomarkers used in newborn screening and how tandem MS methods have recently been applied, in comparison to traditional methods. Similar comparison is done for cancer screening, with emphasis on emerging MS approaches that allow biological fluids, tissues, and breath to be analyzed for the presence of diagnostic metabolites yielding insight for treatment options based on the understanding of prior and current physiological functions of the body.
Determinants and impact of diagnostic interval in bone sarcomas: A retrospective cohort study
Authors: Sasi Archana , Ganguly Shuvadeep , Biswas Bivas , Pushpam Deepam , Kumar Akash , Agarwala Sandeep , Khan Shah Alam , Kumar Venkatesan Sampath , Deo Suryanarayana , Sharma Daya Nand , Bakhshi Sameer 
Published: December 2022

AbstractBackgroundDiagnostic delays in cancers are frequent in developing countries due to poor health infrastructure. Existing literature from developed countries suggests that diagnostic interval in bone sarcomas is primarily dictated by tumour biology with no impact on survival. This study evaluates the social and biological determinants of the diagnostic interval in bone sarcomas in a resource‐challenged setting and assesses its impact on treatment outcomes.MethodsA retrospective single‐institutional study was conducted on patients with high‐grade bone sarcomas recorded in the sarcoma clinic database between 2003 and 2018. Baseline clinical characteristics and treatment outcomes were recorded. Logistic regression was performed to assess the impact of baseline clinical and social characteristics (distance from treating centre and rural vs. urban residence) on the diagnostic interval. Further, the impact of diagnostic interval on histologic response to neoadjuvant chemotherapy, amputation requirement in extremity sarcomas and survival was evaluated.ResultsA total of 1227 patients were included for analysis. The median diagnostic interval was 4 months (3–7 months). Age above 18 years, Ewing sarcoma (ES) diagnosis, absence of fever at presentation and tumour size above 7.5 cm were predictors of a longer diagnostic interval (>4 months). The length of the diagnostic interval did not impact amputation requirement or survival outcomes. However, the proportion of patients with good necrosis post‐neoadjuvant chemotherapy was lower among patients with longer diagnostic intervals (25% vs. 34·16%; p‐value = .04).ConclusionTumour characteristics rather than social factors determined the diagnostic interval. Diagnostic interval did not impact survival outcomes even in a resource‐constrained setting.
Unimpaired highly extensible tough chemically crosslinked hydrogel after experiencing freeze/thaw and boiling processes
Authors: Cotner Stella N. , Shams Es‐haghi Siamak 
Published: December 2022

AbstractA highly extensible, tough, chemically crosslinked double‐network (DN) hydrogel was synthesized from acrylamide. Three samples of this hydrogel were swelled using different solutions. One swelled in water, one in an aqueous glycerol solution, and one in an aqueous sodium chloride solution. The freezing points of the hydrogel samples were determined using differential scanning calorimetry (DSC). Then, the samples underwent controlled freeze–thaw cycles, and their mechanical behavior under loading‐unloading‐reloading large‐strain tensile deformation were analyzed. The results of these mechanical tests indicated that all the data points for deformation cycles coincided, despite the large water content of the samples. This means that no mechanical damage occurred during the deformation process. The results of hydrogel samples boiled in these solutions also showed no damage. Thus, it can be concluded that the tough chemically crosslinked DN hydrogel does not damage under large‐strain tensile deformations even after experiencing harsh environmental conditions, such as freeze/thaw or boiling processes, which makes it a great candidate for applications that involve large temperature variations. The resistance of the DN hydrogel to damage is attributed to the specific molecular architecture of this hydrogel, in that the building block of this material is a loosely crosslinked polymeric network.
Motivated Strategies for Learning Questionnaire (MSLQ): Adaptation, validation, and development of a short form in the Chinese context for mathematics
Authors: Wang Faming , Jiang Chunlian , King Ronnel B. , Leung Shing On 
Published: December 2022

AbstractThe Motivated Strategies for Learning Questionnaire (MSLQ) is one of the most widely used instruments to measure students' motivation and self‐regulated learning. However, the MSLQ was developed and has been predominantly used in the Western context, is a domain‐general measure, and is quite lengthy. Hence, adapting the MSLQ to the Chinese educational context, validating its application in specific subjects, and developing a short form would be an optimal way to improve its accessibility. This study aimed to investigate the psychometric properties of the Chinese version of the MSLQ in mathematics learning (i.e., MSLQ‐C) and develop a short form (i.e., MSLQ‐CS) using set exploratory structural equation modeling. The sample consisted of 563 senior secondary students in China. Results demonstrated that both MSLQ‐C and MSLQ‐CS showed acceptable construct validity, reliability, and concurrent validity. Furthermore, structural relationships and interrelationships among the subscales and their relationships with mathematics achievement were highly similar for MSLQ‐C and MSLQ‐CS. Theoretical and practical implications are discussed.
Morphologically controlled synthesis, characterization, and applications of molybdenum oxide (MoO3) nanoparticles
Authors: Jamil Saba , Zahra Ghulam , Janjua Muhammad Ramzan Saeed Ashraf 
Published: December 2022

AbstractMolybdenum nanoparticles are used as additives in alloys for various applications, such as or in corrosive or high‐vacuum environment. Their properties are completely different than the properties in their bulk. Molybdenum nanoparticles were prepared by hydrothermal technique. MoO3 synthesized nanoparticles were characterized by UV‐visible spectroscopy, SEM, TEM, and XRD. MoO3 had shown its maximum adsorption at wavelength 560 nm. Surface morphology of synthesized MoO3 was studied by using SEM, which showed that MoO3 nanoparticles have shown outgrowth at the edges of strands, while grain size, shape, and distribution was confirmed with TEM, which revealed that the synthesized nanoparticles are fiddle and thin in nature and these particles are made of joint nanosheets. Furthermore, the structure elucidation of synthesized nanoparticles was done by using the XRD calculations, which confirmed that the synthesized particles are MoO3 without impurities. Moreover, MoO3 nanoparticles can be used for photocatalytic properties and biological application.
N‐terminal β‐strand in YAP is critical for stronger binding to scalloped relative to TEAD transcription factor
Authors: Bokhovchuk Fedir , Mesrouze Yannick , Meyerhofer Marco , Fontana Patrizia , Zimmermann Catherine , Villard Frédéric , Erdmann Dirk , Kallen Joerg , Scheufler Clemens , Velez‐Vega Camilo , Chène Patrick 
Published: December 2022

AbstractThe yes‐associated protein (YAP) regulates the transcriptional activity of the TEAD transcription factors that are key in the control of organ morphogenesis. YAP interacts with TEAD via three secondary structure elements: a β‐strand, an α‐helix, and an Ω‐loop. Earlier results have shown that the β‐strand has only a marginal contribution in the YAP:TEAD interaction, but we show here that it significantly enhances the affinity of YAP for the Drosophila homolog of TEAD, scalloped (Sd). Nuclear magnetic resonance shows that the β‐strand adopts a more rigid conformation once bound to Sd; pre‐steady state kinetic measurements show that the YAP:Sd complex is more stable. Although the crystal structures of the YAP:TEAD and YAP:Sd complexes reveal no differences at the binding interface that could explain these results. Molecular Dynamics simulations are in line with our experimental findings regarding β‐strand stability and overall binding affinity of YAP to TEAD and Sd. In particular, RMSF, correlated motion and MMGBSA analyses suggest that β‐sheet fluctuations play a relevant role in YAP53‐57 β‐strand dissociation from TEAD4 and contribute to the lower affinity of YAP for TEAD4. Identifying a clear mechanism leading to the difference in YAP's β‐strand stability proved to be challenging, pointing to the potential relevance of multiple modest structural changes or fluctuations for regulation of binding affinity.
Parametric and nonparametric methods for confidence intervals and sample size planning for win probability in parallel‐group randomized trials with Likert item and Likert scale data
Authors: Zou Guangyong , Zou Lily , Qiu Shi‐fang 
Published: December 2022

AbstractData on the Likert scale are ubiquitous in medical research, including randomized trials. Statistical analysis of such data may be conducted using the means of raw scores or the rank information of the scores. In the context of parallel‐group randomized trials, we quantify treatment effects by the probability that a subject in the treatment group has a better score than (or a win over) a subject in the control group. Asymptotic parametric and nonparametric confidence intervals for this win probability and associated sample size formulas are derived for studies with only follow‐up scores, and those with both baseline and follow‐up measurements. We assessed the performance of both the parametric and nonparametric approaches using simulation studies based on real studies with Likert item and Likert scale data. The simulation results demonstrate that even without baseline adjustment, the parametric methods did not perform well, in terms of bias, interval coverage percentage, balance of tail error, and assurance of achieving a pre‐specified precision. In contrast, the nonparametric approach performed very well for both the unadjusted and adjusted win probability. We illustrate the methods with two examples: one using Likert item data and the other using Like scale data. We conclude that non‐parametric methods are preferable for two‐group randomization trials with Likert data. Illustrative SAS code for the nonparametric approach using existing procedures is provided.
Synthesis of Quinoline‐Pyrene Derivatives and Theoretical Investigation of Their Fluorescence and Electronic Properties
Authors: Gümüş Ayşegül , Gümüş Selçuk 
Published: December 2022

AbstractSynthesis of novel fluorescent quinoline‐pyrene conjugates is described. The key intermediates 2‐substituted 8‐propynyloxy quinoline and azidomethyl pyrene were connected with triazole bridge by 1,3‐dipolar alkyne‐azide cycloaddition reaction. Density functional theory methodology with B3LYP/6‐311++G(d,p) basis set was applied computationally to gather information about the structural and electronic properties of the quinoline‐pyrene compounds. In addition, the metal coordination properties of the triazole bridged molecules were investigated through interactions with several cations. The effect of metal coordination on the stability of the complexes have also been discussed through computations on chelatoaromaticity.
Photoswitching Properties of 5‐Methoxy‐2‐ (2‐phenyldiazenyl) Pyridine
Authors: Foy Justin T. , Ta Nicholas , Hoyt Johnathon , Staples Richard J. , Ehm Christian 
Published: December 2022

AbstractHeteroaryl azobenzene molecular switches often have superior performance compared to their parent azobenzene derivatives. Herein, we report the efficient photoswitching of phenylazopyridine 5‐methoxy‐2‐(2‐phenyldiazenyl)pyridine using 1H NMR and UV/vis spectroscopy demonstrating >92 % Z at the photostationary state and a thermal half‐life of 6.3 days at room temperature. Kinetic studies are in good agreement with the DFT predicted isomerization barrier.
Exposure to potentially morally injurious events, disruption in assumptive world, moral injury symptoms, and psychological distress among Israeli female veterans
Authors: Zerach Gadi , Levi‐Belz Yossi 
Published: December 2022

AbstractExposure to potentially morally injurious events (PMIEs) during military service is associated with mental health problems. However, knowledge about these associations and possible mechanisms of effect among female combat veterans is sparse. This study examines associations between PMIEs, posttraumatic stress disorder (PTSD), complex PTSD, depression and anxiety symptoms among female veterans, as well as the mediating role of disruption in assumptive world and moral injury (MI) symptoms. A volunteer sample of Israeli female combat veterans (n = 885) and non‐combat veterans (n = 728) responded to self‐report questionnaires in a cross‐sectional design study. Results show that combat veterans reported higher levels of PMIEs, PTSD and MI symptoms, but not CPTSD, depression and anxiety symptoms, as compared to non‐combat veterans. Importantly, PMIEs was indirectly associated with PTSD, complex PTSD, depression and anxiety symptoms through serial mediators of disruption in assumptive world and MI symptoms. This study emphasized the exposure to PMIEs and its posttraumatic sequelae among female combat veterans as compared to non‐combat veterans. Our findings also suggest that future longitudinal studies should examine the mediating role of disruption in assumptive world and MI symptoms for the deleterious effects of exposure to PMIEs during military service.
Coupling Reversible Clustering of DNA‐Coated Gold Nanoparticles with Chemothermal Cycloaddition Reaction
Authors: Kruse Joscha , Sanromán‐Iglesias Maria , Marauri Aimar , Rivilla Ivan , Grzelczak Marek 
Published: December 2022

AbstractStimuli‐responsive, optically‐active colloidal systems are convenient signal transducers capable of monitoring environmental changes at the nanoscale. We report on the coupling of chemo‐thermal cycloaddition reaction with temperature‐sensitive, DNA‐coated gold nanoparticles. We found that the concentration of chemical fuel, dictating the temperature of the mixture, is a primary ingredient in controlling the extent of the reversible clustering of gold nanoparticles. Our results show that rational coupling of chemical and colloidal systems can open up new possibilities in tracking the change of local temperature using aggregation/redispersion of nanoparticles.
Limits to adaptation: Building an integrated research agenda
Authors: Berkhout Frans , Dow Kirstin 
Published: December 2022

AbstractThe IPCC's Sixth Assessment Report Working Group II report of (2022) has brought greater attention to the issue of limits to the capacity to adapt to climate change. But the report also showed that research in the field continues to be fragmented and under‐developed, and that the problem of limits is not widely considered in policy. In this paper, we argue for a more coherent, interdisciplinary approach to research on adaptation limits, linked to the concept of transformative adaptation. A risk‐based approach to adaptation limits offers a framework to deepen, broaden and connect research which responds to the needs of policymakers. We set out four promising directions for future research on: the dimensions of limits; the dynamics of limits; formalization of research on limits; and ethics and justice challenges underpinning adaptation limits.This article is categorized under:
Climate Economics > Economics and Climate Change
Vulnerability and Adaptation to Climate Change > Learning from Cases and Analogies
Climate, Nature, and Ethics > Climate Change and Global Justice
The Sequence Makes the Difference: On the Reaction of Phosphorus‐centered Biradical [⋅P(μ‐N‐tBuPh3C)2P⋅] with Tolan
Authors: Berthold Sebastian , Wustrack Ronald , Villinger Alexander , Schulz Axel 
Published: December 2022

AbstractThe biradical [⋅P(μ‐N‐tBuPh3C)2P⋅] (6T) can be generated by reduction of a cyclic dichlorophosphane, [ClP(μ‐N‐tBuPh3C)2PCl], utilizing magnesium. If this biradical is treated with alkynes, e. g. tolan, Ph−C≡C−Ph, the addition product, a [2.1.1.] bicyclic species, [P(μ‐N‐tBuPh3C)2P(Ph−C=C−Ph)] (7), is obtained. However, if the reduction process with magnesium is carried out in the presence of tolan the reaction mixture finds a different reaction channel, ultimately yielding a magnesium(II) double salt, including a [Mg(THF)2]2+ cation with a [tBuPh3C−N−P−N−CtBuPh3]− and a novel tolan‐stabilized [(PhC=CPh)P−N−P(PhC=CPh)]− anion as counterions. This novel anion can also be conceived as anionic [2.2.1] bicycle with a [N]− ion trans‐annular bridging a 1,4‐diphosphabenzene.