bluuebunny/crossref_metadata_2025_split huggingface dataset:
Liderazgo indígena y mass media. El caso de Alberto Pizango en la política peruana
Authors: Romio Silvia 
Published: September 2022

A lo largo de últimos cincuenta años, el liderazgo indígena ha pasado por importantes transformaciones. Dicha trayectoria ha estado dominada por un proceso de fusión y reelaboración de diferentes modelos de liderazgos provenientes de los contextos locales, nacionales y globales. En todo ello, el uso creativo de las herramientas visuales y de los mass media ha jugado un rol fundamental. Al interior del escenario político peruano, la figura de Alberto Pizango Chota, líder shawi de la organización Aidesep, ha marcado un antecedente importante en este sentido. Su caso se impone como un terreno de estudio ejemplar acerca de las extraordinarias posibilidades para un líder indígena actual de uso de la imagen, fabricación de la estética y elaboración de nuevos códigos expresivos. Todos estos son elementos que el liderazgo amazónico ontemporáneo puede proponer y divulgar a través de las tecnologías digitales y las relaciones con losmedios masivos de comunicación.
Associations of 4 Geographic Social Vulnerability Indices With US COVID-19 Incidence and Mortality
Authors: Tipirneni Renuka , Schmidt Harald , Lantz Paula M. , Karmakar Monita 
Published: September 2022

Objectives. To examine and compare how 4 indices of population-level social disadvantage—the Social Vulnerability Index (SVI), the Area Deprivation Index (ADI), the COVID-19 Community Vulnerability Index (CCVI), and the Minority Health–Social Vulnerability Index (MH-SVI)—are associated with COVID-19 outcomes. Methods. Spatial autoregressive models adjusted for population density, urbanicity, and state fixed effects were used to estimate associations of county-level SVI, MH-SVI, CCVI, and ADI values with COVID-19 incidence and mortality. Results. All 4 disadvantage indices had similar positive associations with COVID-19 incidence. Each index was also significantly associated with COVID-19 mortality, but the ADI had a stronger association than the CCVI, MH-SVI, and SVI. Conclusions. Despite differences in component measures and weighting, all 4 of the indices we assessed demonstrated associations between greater disadvantage and COVID-19 incidence and mortality. Public Health Implications. Our findings suggest that each of the 4 disadvantage indices can be used to assist public health leaders in targeting ongoing first-dose and booster or third-dose vaccines as well as new vaccines or other resources to regions most vulnerable to negative COVID-19 outcomes, weighing potential tradeoffs in their political and practical acceptability. (Am J Public Health. 2022;112(11):1584–1588. https://doi.org/10.2105/AJPH.2022.307018 )
Risks factors for virus shedding period of COVID-19 in maintenance hemodialysis patients: a retrospective cohort study
Authors: Xu Lili , Wu Xiaojin , Zhang Muyin , Li Xin , Hao Xu , Li Hao , Qiao Panpan , Wang Weiming 
Published: September 2022

Abstract
The authors have requested that this preprint be removed from Research Square.
Synthetic ribonucleoprotein granules regulate translation of a target mRNA in living cells
Authors: Eghtasadi Seyed , Shapiro Daniel , Deshpande Sonal , Min Junseon , Fiflis David , Rohm Dahlia , Dai YIfan , Asokan Aravind , Gersbach Charles , Chilkoti Ashutosh 
Published: September 2022

Abstract

Biomolecular condensates composed of proteins and RNA, known as ribonucleoprotein granules, are one approach by which cells regulate post-transcriptional gene expression. The formation of ribonucleoprotein granules typically involves the liquid-liquid phase separation of intrinsically disordered proteins with a target mRNA, sequestering the mRNA into the condensate. This sequestration regulates gene expression by inhibiting translation or facilitating RNA processing, such as splicing. Here, we designed a recombinant fusion of the human Pumilio2 homology domain (Pum2) RNA-binding protein and a synthetic intrinsically disordered protein that exhibits liquid-liquid phase separation to create synthetic ribonucleoprotein granules that extrinsically regulate the expression of a target gene. We show that this fusion protein selectively binds an RNA transcript of interest that contains a Pum2-binding RNA sequence at its 3’-end and sequesters the mRNA within a biomolecular condensate. Sequestration of a target mRNA within the condensate largely reduces the translation of the target RNA in protocells and in E. coli compared to cells that do not sequester the target mRNA in a synthetic condensate. We demonstrate that the viability of E. coli that harbor a cytotoxic protein can be rescued by sequestering the mRNA encoding the cytotoxic protein within a synthetic condensate. Finally, we use RNA-seq to determine that the target RNA of interest is preferentially sequestered in synthetic ribonucleoprotein granules. This approach enables modulation of cell function via the formation of a synthetic biomolecular condensate that spatiotemporally regulates the expression of a target protein.
Involvement of DNA methylation in regulating the growth of Arabidopsis thaliana seedling exposed to lanthanum(III) at environmental relevant levels
Authors: Chen Qi , Sheng Landi , Guo Menglei , Li Yajie , Dai Wenhao , Wang Lihong 
Published: September 2022

Abstract
Rare earth elements (REEs) are excessively enriched in the environment. Epigenetic changes at the level of DNA methylation is often rapidly established in plant’s response to environmental factors. However, how the level of DNA methylation changes and then regulates plant growth in REE exposure at environmental relevant levels is still a mystery. Here, this mystery was initially revealed in Arabidopsis thaliana exposed to lanthanum [La(III), a widespread REE] at environmental relevant levels (0, 30 and 80 µM). The results showed that the DNA methylation levels, biomarker of one-carbon metabolism providing methyl for DNA methylation (S-adenosylmethionine content, S-adenosyl homocysteine content, the ratio of S-adenosylmethionine to S-adenosyl homocysteine] and plant growth did not change under a short-term La(III) exposure; with increased exposure time, the DNA methylation levels increased, along with the reduced one-carbon metabolism and improved growth (plant height, leaf number, leaf area, primary root length, lateral root number, and root hair number). However, the opposite changes were observed in the DNA methylation levels, one-carbon metabolism and growth under high-dose La(III) exposure. After adding DNA methylation inhibitor, La(III)-induced changes in plant growth were relieved, indicating that plant growth can be regulated by DNA methylation in the response to environmental REEs. Our study would provide references for revealing the mechanism of REEs acting on plants, scientifically assessing the environmental risk of REEs and alleviating the negative effects of REEs pollution.
Speaker verification based on 3D variational self-coding multi-tasking adversarial network
Authors: Liao Hong-heng , Xue Ya-juan 
Published: September 2022

Abstract

In this paper, we leverage the generative adversarial mechanism and multi-task optimization strategy to propose an architecture to enhance the accuracy of speaker verification. The proposed model can recognize both speaker's original features and their reconstructed features on the basis of the variational auto- encoder (VAE) and generative adversarial network (GAN). We term our method Multitasking Variational Autoencoder Generative Adversarial Networks (MTVAEGAN). The encoder in VAE aims at extracting target speech features and classifying to a specific target. The purpose of the generator in GAN is to generate perturbations that could make the target network misclassified as a specific target, while simultaneously fooling the discriminators by treating the adversarial examples as a beguine example. The discriminator exists to distinguish crafted examples from genuine samples. The classification is to classify the reconstructed data and drive the generator to produce more precise speech features. Experiments on short utterances demonstrates that MTVAEGAN increases the verification accuracy (ACC) by 11.52% (relatively) and 2.78% (relatively) over conventional 3DCNN method and MTGAN method respectively.
Association of Carotid and Vetebral Arterial Variations with Risk of Ischemic Stroke
Authors: Zhou Rui , Li Xiaoxiong , Li Jinping , Ma Linqiu , Hou Mingliang , Liu Dong , Tao Yong , Chen Le , Dong Shuyang , Yu Ke , Cui Ming , Hong Wenjuan , Wang Congguo , Tang Mingshan , LI Yafei , Cao Hongyuan , Yu Minmin , Yang Yonggao , Zhang Zhihong , Yang Heng , Zhong Hua , Yan Jiachuan , Li Xunjun , Zhan Qunling , Zhou Huadong 
Published: September 2022

Abstract
Background
With the wide application of computed tomography angiography (CTA), it is found that carotid and vertebral arterial variation has a high incidence in ischemic stroke. The aim of our study was to investigate the relationship between carotid and vertebral artery variants and the risk of ischemic stroke through a prospective and large sample study.
Methods
Carotid and vertebral arterial variations in consecutive subjects were prospectively studied using CTA. Variations of the carotid and vertebral arteries were classified into tortuosity, kinking and coiling using the criteria established by Weibel and Fields. Tortuosity is defined as a non-rectilinear stretch of an artery with an angulation > 90–165°. Kinking is described as an acute angle between two arterial segments ≤ 90°. Coiling is defined as a 360°. We analyzed the association between arterial variations and the risk of stroke using multivariate Cox proportional-hazards models.
Results
A total of 29319 subjects aged 50 years or older (14391 males and 14928 females) were examined for carotid and vertebral arterial variations. Among all subjects who completed the five-year follow-up, 1841 (6.3%) cases of stroke were detected. The proportion of kinking and coiling in the carotid and vertebral arteries in subjects with stroke was higher than that in subjects without stroke. Following adjustments for potential confounders, kinking and coiling of the carotid artery were significantly associated with stroke risk (HR = 1.47; 95% CI 1.32 to 1.64; P < 0.001), and kinking and coiling of the vertebral artery were also significantly associated with stroke risk (HR = 1.36; 95% CI 1.22 to 1.51; P < 0.001).
Conclusions
The results of the current study indicate that kinking and coiling in the carotid and vertebral arterial variations are associated with a significantly increased risk of ischemic stroke.
Discovery of extracellular electron uptake by the lactic acid bacterium Lactiplantibacillus plantarum
Authors: Tejedor-Sanz Sara , Li Siliang , Kundu Biki , Ajo-Franklin Caroline 
Published: September 2022

Abstract
Microorganisms utilize different electron donors and acceptors to gain energy from redox reactions. A subset of microorganisms that perform respiration can endogenously utilize insoluble electron donors, such as Fe(II) or a cathode, in a process called extracellular electron transfer (EET). However, it is unknown whether similar endogenous EET can be performed by primarily fermentative species like lactic acid bacteria. We report for the first time EET from a cathode by Lactiplantibacillus plantarum, a primarily fermentative bacteria found in the gut of mammals and in fermented foods. L. plantarum consumed electrons from a cathode and coupled this oxidation to the reduction of both an endogenous organic and an exogenous inorganic electron acceptor. This EET from a cathode reroutes glucose fermentation towards ATP generation routes and provides cells with a higher viability upon sugar exhaustion. Moreover, the associated genes and cofactors indicate that this pathway is distinct from any other known electron transport chains within the group of lactic acid bacteria. Our results expand our knowledge of the diversity of electroactive species and of the metabolic and bioenergetic strategies used by lactic acid bacteria.
Differential Subordination and Superordination Results for Analytic function associated with Pascal distribution
Authors: Saritha K. , Thilagavathi K. 
Published: September 2022

Abstract
In the present investigation, we obtain some subordination and superordinatin results involving Pascal distribution for certain normalized analytic functions in the open unit disk.Also we estimate the Sandwich results for the above class. AMS Subject Classification: 30C45, 30C50, 30C20, 30C80.
Manufacturing feature recognition method based on graph and minimum non-intersection feature volume suppression
Authors: Yan Hongxiang , Yan Chunping , Yan Ping , Hu Yuping , Liu Shibin 
Published: September 2022

Abstract
Automatic manufacturing feature recognition (AFR) is a critical technology for realizing CAD/CAPP/CAM integration in the era of intelligent manufacturing. Despite the numerous feature recognition approaches that have been proposed, the recognition of intersecting features remains a challenge. The most important reason is that the boundaries of features and their geometric topological information are altered or destroyed when interacting with other features. To address this problem, this paper proposes a manufacturing feature recognition method based on graph and minimum non-intersection feature volume suppression. Firstly, the geometric and topological information of a part is extracted and represented as an attributed adjacency graph. Then, a subgraph isomorphism algorithm is designed to recognize the features corresponding to each subgraph. After that, a method to construct and suppress the minimum non-intersection volume of the recognized features is introduced to repair the boundaries of intersecting features. On this basis, the intersecting features on the solid model are separated and recognized at different stages. The experimental results indicate that the proposed approach is effective in recognizing intersection features. Moreover, the recognition result of the proposed method incorporates the surface and volume of a feature, providing enriched feature information for engineering applications.
Synthesis of new coumarin based acetohydrazones and their correspounding oxadiazoles and oxadiazolines and the investigation of their keto-enol and/or amide–iminol tautomerization
Authors: Baharvand Narjes , Mottaghinejad Enayatollah , fardarani Mohsen Sargordan , Doust Reza Hosseini 
Published: September 2022

Abstract

Here we report the synthesis, structural identification and tautomeric behavior of new series of coumarin based hydrazide-hydrazones and their 1,3,4-oxadiazole and oxadiazoline derivatives. In fact The synthesis of 1,3,4-oxadiazoles and oxadiazoline bearing coumarin ring was intended for deducing the isomerization-tautomerization of their hydrazone precursors. Convectional synthesis of several coumarin-oxadiazole derivatives from starting compound, 4-Methylcoumarinyl-7-yl-oxymethyl acetic acid hydrazide has been accomplished. Both types of hydrogens: the hydrazone N-H and methylene protons can take part to tautomeric isomerization equilibria. According to the nmr investigation we found that the keto-enol tautomerization is more favored than amide-iminol. This concept was further established by converting the hydrazones to the corresponding 1,3,4-oxadiazoles and oxadiazolines according to the modified procedures.
Evaluation of the postoperative risk of deep tissue injury to the lower extremities following surgery in the lithotomy position
Authors: Yukizawa Yohei , Kobayashi Naomi , Kamono Emi , Takagawa Shu , Honda Hideki , Inaba Yutaka 
Published: September 2022

Abstract
Aims
The aim of this study was to determine the incidence of deep tissue injury (DTI) and its potential risk factors after surgery in the lithotomy position.
Methods
All patients who underwent surgery in the lithotomy position under general anesthesia at a single center between January 2015 and December 2019 were retrospectively evaluated. The medical records of these patients were reviewed, and patient demographic and clinical characteristics, surgical data, and occurrence of DTI were recorded.
Results
During the study period, 5146 patients, 2055 (39.9%) males and 3091 (60.1%) females, of mean age 57.3 ± 17.4 years, underwent surgery in the lithotomy position. Seven (0.14%) patients developed DTI on their calf following surgery. All presented with severe pain and swelling, requiring prolonged hospital stay. Multivariate analysis showed that male (odds ratio [OR]: 11.43; 95% confidence interval [CI]: 1.15–113.34, p = 0.037), higher BMI (OR: 1.32; 95% CI: 1.17–1.50, p = 0.0001), and longer operation time (OR: 1.01; 95% CI: 1.004–1.014, p = 0.0002) were independent risk factors for postoperative DTI. Optimal cut-off values for BMI and operation time were 23.5 kg/m2 (sensitivity 100%, specificity 64%) and 285 minutes (sensitivity 100%, specificity 90%), respectively.
Conclusion
Factors significantly associated with DTI include male sex, higher BMI, and prolonged operation time.
Numerical Modeling of soil-landscape relationships using diversity indices and conditional probability: A case study from an Iranian arid region
Authors: Bagheri-Bodaghabadi Mohsen , Jafari Azam , Zeraatpisheh Mojtaba , Owliaie Hamidreza , Finke Peter , Xu Ming 
Published: September 2022

Abstract

We quantified some mental and qualitative concepts about the soil-landscape relationships by numerical analysis of landforms in soil identification using diversity indices and conditional probability with a given sample size in Darab and Khosuyeh plains (a rural district) in the south of Iran in Fars province. The geomorphology map was prepared based on the Zinck method and used as a basic design for soil sampling. Finally, 200 soil profiles (0-150 cm) were excavated and described. Diversity indices and conditional probability were calculated based on soil taxonomic and geomorphological hierarchies. The results showed that diversity indices increase from landscape to landform level. The lowest and highest diversity indices were obtained at each geomorphic level for the soil order and soil family. The geomorphic diversity based on the soil taxonomy hierarchy showed that soil orders, including Entisols and Inceptisols, are observed in various landscapes and landforms. In contrast, some soil classes, such as Mollisols and its lower levels (suborder, great group, etc.), did not have geomorphic diversity. The conditional probability based on the geomorphological hierarchy indicated that the presence possibility of specific soil at the higher level (landscape) is less than, the lower level (landform), which indicates the more homogeneity of soils at lower geomorphic levels. However, the probability of observing a certain geoform increased according to the soil classification hierarchy, consistent with the results of diversity indices. The efficiency of diversity indices and conditional probability in showing the distribution and possibility of soil separation depends on the alignment of soil and geomorphological processes and the diagnosis of these processes.
Antioxidant and cytotoxic properties of nano and fermented-nano powders of wheat and rice by-products
Authors: Yousif El-Sayed , Yaseen Attia , Abdel-Fatah Abdel-Fatah , Shouk Abdel-Hafeez , Gdallah Mohamed , Mohammad Ayman 
Published: September 2022

Abstract
The use of fermentation and nano technology can promote the absorption efficiency and improve the functionality and the added value of cereal by-products. In this study, nano and fermented-nano powders of wheat and rice by-products were prepared by superfine grinding of raw and solid-state fermented materials. Effects of fermentation and superfine grinding on phytochemical, phenolic acids profile, antioxidant and cytotoxic activity were investigated. The results revealed that phenolic contents of fermented-nano wheat bran (FNWB), fermented-nano wheat germ (FNWG) and fermented-nano rice bran (FNRB) increased by 40.5, 59.2 and 27.9%, respectively compared to their raw samples. The free, conjugated and bound forms of most identified phenolic acids apparently increased. Also, the antioxidant activity of nano and fermented-nano forms significantly increased compared to raw materials. The cytotoxic activity of ultrafine ground samples increased compared to raw materials. NRB extract was the most effective treatment with IC50 value of 4.10 mg/mL. These results indicate that superfine grinding and solid state fermentation altered the rigid structure of wheat and rice by-products and increased their bioactivity through increasing the releasable bioactive molecules.
Neighborhood Matters! Evidence from Michigan Public Schools
Authors: Misra Kaustav , Linskey Evan 
Published: September 2022

Abstract
Discussion about improving public school performance is not a new debate. Questioning internal factors like teacher quality, gender ratio, class size, and students’ socioeconomic backgrounds to improve school performance are well researched but looking at it from community perspectives is a recently developed interest. Following Misra, Grimes and Rogers (2013), we are also trying to understand the importance of community where public schools operate. We randomly select three key community attributes: religious institution, higher education, and liquor license to understand how these external factors influence public school performance. Again, similar to Misra, Grimes and Rogers (2012), this paper uses Geographical Information Systems (GIS) to develop the community around a public school. Then we employed regression analysis to evaluate the relationship between the community attributes on standardized test scores. The results from this paper will provide Michigan policy makers and education administrators a different perspective to deal with statewide public school performance.
A comparative study of path loss models in the ultra-high frequency band in a vegetated environment
Authors: Obot Enobong Patrick , Onuu Michael Ugwu , Arikpo John Ubi , Nwosu Christian Nlemchukwu 
Published: September 2022

Abstract
With the additional challenge of forecasting a transmitter’s radio coverage region, radio propagation models concentrate on path loss realization. Empirical approaches are used in radio propagation models. Path loss models are essential in mobile radio systems for effective planning, as well as for calculations of interference, frequency assignments, and cell parameters-the fundamental building blocks of the network planning process. For a given scenario, they are created using a substantial amount of data collected. This work presents a comparative study of path loss models in the ultra-high frequency (UHF) band in vegetated environments of three cities in South Eastern Nigeria. The applicability of the computed empirical propagation models was confirmed using the practical measured data collected from the fields. The findings revealed that, in general, all the vegetated environments had path loss that was overestimated by the SUI and ECC-33 models. For any vegetated region of South Eastern Nigeria, the Hata’s model outperforms the other propagation models, with mean square error (MSE) values of 4.08 dB, 5.50 dB, and 3.75 dB respectively. The MSE value is below 6 dB, thus it is suitable for signal prediction.