bluuebunny/crossref_metadata_2025_split huggingface dataset:
Iron‐doped Ag/Ni2(CO3)(OH)2 hierarchical microtubes for highly efficient water oxidation
Authors: Zhang Huiwen , Liu Shuxuan , Hu Enlai , Yang Yunfei , Zhang Huimin , Zhu Yuting , Yan Lijing , Gao Xuehui , Zhang Jing , Lin Zhan 
Published: April 2022

AbstractDoping of foreign atoms and construction of unique structures are considered as effective approaches to design high‐activity and strong‐durability electrocatalysts. Herein, we report Fe‐doped nickel hydroxide carbonate hierarchical microtubes with Ag nanoparticles (denoted Ag/NiFeHC HMTs) through hydrolysis precipitation process. Experimental tests and density functional theory calculations reveal that Fe doping can tune the electron configuration to enhance the conductivity, markedly improve the electrochemical surface area to expose more active sites, and act as reactive centers to lower the free energy of the rate determination step. In addition, the unique hierarchical structure can also offer active sites and excellent cycling stability. Benefitting from these advantages, the as‐obtained Ag/NiFeHC HMTs show excellent oxygen evolution reaction activity, with an overpotential of 208 mV at 10 mA cm−2 in 1.0 M KOH. Also, it could achieve long‐term stability at a current density of 20 mA cm−2 for 24 h.
Se‐(Fluoromethyl) Benzenesulfonoselenoates: Shelf‐Stable, Easily Available Reagents for Monofluoromethylselenolation
Authors: Guo Rui‐Li , Zhang Xing‐Long , Bu Xian‐Pan , Wang Meng‐Yue , Zhao Bao‐Yin , Gao Ya‐Ru , Jia Qiong , Wang Yong‐Qiang 
Published: April 2022

AbstractA new class of electrophilic monofluoromethylselenolation reagents, Se‐(fluoromethyl) benzenesulfonoselenoates, has been developed. They can be readily prepared from sodium benzenesulfinates, Se powder and ClCFH2 in one step under mild reaction conditions. Se‐(fluoromethyl) benzenesulfonoselenoates are efficient electrophilic monofluoromethylselenolation reagents for a wide range of nucleophiles including indole, 6‐azaindole, pyrrole, thiophene, electron‐rich arene, aryl boronic acid and alkyne. The monofluoromethylselenolation approach features mild and environmentally friendly reaction conditions, good tolerance of various functional groups, and broad substrate scope.
Promising Therapeutic Approach for SARS‐CoV‐2 Infections by Using a Rutin‐Based Combination Therapy
Authors: Mazik Monika 
Published: April 2022

AbstractThe development of new therapeutic approaches for SARS‐CoV‐2 infections is of particular current importance. The combination therapy proposed here is based on already proven, safe and inexpensive compounds. The natural compound rutin, one of the six therapy components, has the potential to inhibit both viral and host cell targets. In addition, this therapy involves the use of acetylsalicylic acid, vitamin C and vitamin D3, which should be administered together with calcium and magnesium. The importance of each component is briefly described in this article. Due to multiple anti‐infective properties of rutin, it provides a basis for combating a SARS‐CoV‐2 infection as well as various viral and bacterial co‐infections. There are strong indications for a good effect of this simple combination therapy, especially in the early stages of infection. It has the potential to be of interest both prophylactically and therapeutically, and offers the possibility of protection against severe disease progression.
YTHDF2 interference suppresses the EMT of cervical cancer cells and enhances cisplatin chemosensitivity by regulating AXIN1
Authors: Wu Min , Chen Guozhong , Liao Xiaowen , Xiao Lihua , Zheng Jianqing 
Published: April 2022

AbstractM6A reader YTH structural domain family 2 (YTHDF2) has been recognized to play an oncogenic role in numerous tumors, but its role in cervical cancer has not been extensively discussed yet. This paper was designed to explore the role of YTHDF2 in cervical cancer and identify its underlying mechanism. The expression of YTHDF2 was first determined in cervical cancer cells by quantitative reverse‐transcription polymerase chain reaction and western blot. Then, the migration, invasion, and epithelial–mesenchymal transition (EMT) process were observed in YTHDF2‐knockdown Hela cells using wound healing, transwell and immunofluorescence assays. The cisplatin chemosensitivity of Hela cells was also investigated by assessing cell activity with cell counting kit‐8 and TUNEL (terminal deoxynucleotidyl transferase‐mediated dUTP nick end labeling). After MeRIP‐Seq assay and actinomycin D treatment to confirm the binding relationship between YTHDF2 and AXIN1, the migration, invasion, EMT process, and cisplatin chemosensitivity were assessed again in Hela cells silenced by YTHDF2 and AXIN1 or treated with Wnt agonist. YTHDF2 was increased in cervical cancer cells, and depletion of YTHDF2 led to reduced migration, invasion and EMT process but enhanced chemosensitivity of cisplatin in Hela cells. Furthermore, YTHDF2 could bind to and stabilize the expression of AXIN1. When the YTHDF2‐knockdown Hela cells were further transfected with AXIN1 knockdown or treated with Wnt agonist, the effects of YTHDF2 knockdown on the migration, invasion and EMT process were partially abolished, together with reduced cisplatin chemosensitivity. To sum up, we reported that YTHDF2 interference could suppress the EMT of cervical cancer cells and enhance cisplatin chemosensitivity by regulating AXIN1.
Sensor technology in eating disorders research: A systematic review
Authors: Presseller Emily K. , Patarinski Anna Gabrielle G. , Fan Stephanie C. , Lampe Elizabeth W. , Juarascio Adrienne S. 
Published: April 2022

AbstractObjectiveSensor technologies offer exciting potential to objectively measure psychopathological correlates of eating pathology and eating disorder (ED) research utilizing sensors has rapidly proliferated in the past several years. The aims of the present review are: (1) characterize the types of sensors that have been utilized in ED research, (2) identify the psychopathological factors relevant to EDs that have been assessed using sensors, (3) describe the data supporting the validity and reliability of these sensors, (4) discuss limitations associated with these sensors, and (5) identify gaps that persist within the ED literature with regard to use of sensor technologies.MethodA systematic search was conducted of PubMed, PsycINFO, Web of Science, ProQuest, and “gray” literature sources. Eligible publications were empirical studies that utilized sensors to measure at least one psychological variable among clinical ED populations.ResultsSensors have been utilized with ED samples to measure eating behaviors, physical activity, sleep, autonomic nervous system activity, eyeblink startle response, visual attention, and visual‐haptic object integration. The reliability and validity of these sensors varies widely and there are a number of significant gaps that remain in the literature with regard to the types of sensors utilized, context in which sensors have been used, and populations studied.DiscussionThe existing literature utilizing sensors within ED research largely support the feasibility and acceptability of these tools. Sensors should continue to be utilized within the field, with a specific focus on examining the reliability and validity of these tools within ED samples and increasing the diversity of samples studied.Public Significance StatementSensor technologies, such as those included in modern smartwatches, offer new opportunities to measure factors that may maintain or contribute to symptoms of eating disorders. This article describes the types of sensors that have been used in eating disorders research, challenges that may arise in using these sensors, and discusses new applications of these sensors that may be pursued in future research.
The roles of negative emotion intensity, negative emotion differentiation, and self‐compassion in loss of control eating
Authors: Bicaker Ege , Lane Sean P. , Sadikaj Gentiana , Racine Sarah E. 
Published: April 2022

AbstractObjectiveNegative affect intensity is robustly related to binge eating, but the relationship between negative emotion differentiation (i.e., the ability to differentiate negatively‐valenced emotions) and binge eating is unclear. Further, little is known about factors that might reduce emotion intensity and/or enhance emotion differentiation, thereby reducing binge eating. Self‐compassion is consistently linked to less binge eating, which may be due to decreased negative affect and/or an enhanced ability to differentiate emotions. The current study examined the roles of negative emotion intensity, negative emotion differentiation, and self‐compassion in binge eating using ecological momentary assessment.MethodParticipants were 201 university students (52.2% female) who completed questionnaires assessing affect seven times a day, and engagement in loss of control (LOC) eating episodes at the end of each day, for 10 days. The average of sadness, fear, guilt, and hostility subscales represented negative emotion intensity; intraclass correlations across negative affect subscales defined negative emotion differentiation. Both daily (i.e., within‐person) and trait (i.e., between‐person) emotion variables were examined as predictors.ResultsBetween‐person negative emotion intensity, but not negative emotion differentiation, significantly predicted LOC eating occurrence. Self‐compassion had a significant effect on LOC eating frequency, and this relationship was partially mediated via negative emotion intensity, but not via negative emotion differentiation.DiscussionLower levels of negative emotion intensity partially account for the relationship between greater self‐compassion and less frequent LOC eating. These findings highlight the importance of cultivating self‐compassion to down‐regulate negative emotions and to reduce LOC eating.Public significance statementOur findings suggest that university students who approach their limitations compassionately experience fewer negative emotions in daily life and engage in less loss of control eating. Lower levels of negative affect partially explain this relationship between self‐compassion and loss of control eating. These results highlight the importance of cultivating an understanding and a compassionate attitude toward oneself for reducing eating pathology.
Optimizing relapse prevention and changing habits (REACH+) in anorexia nervosa
Authors: Steinglass Joanna E. , Attia Evelyn , Glasofer Deborah R. , Wang Yuanjia , Ruggiero Julia , Walsh B. Timothy , Thomas J. Graham 
Published: April 2022

AbstractIntroductionRelapse rates in anorexia nervosa (AN) are high, even after full weight restoration. This study aims to develop a relapse prevention treatment that specifically addresses persistent maladaptive behaviors (habits). Relapse Prevention and Changing Habits (REACH+) aims to support patients in developing routines that promote weight maintenance, encourage health, and challenge habits that perpetuate illness. The clinical trial design uses the Multiphase Optimization STrategy (MOST) framework to efficiently identify which components of treatment contribute to positive outcomes.MethodsParticipants will be 60 adults with AN who have achieved weight restoration in an inpatient setting. Treatment will consist of 6 months of outpatient telehealth sessions. REACH+ consists of behavior, cognitive, and motivation components, as well as food monitoring and a skill consolidation phase. A specialized online platform extends therapy between sessions. Participants will be randomly assigned to different versions of each component in a fractional factorial design. Outcomes will focus on maintenance of remission, measured by rate of weight loss and end‐of‐trial status. Interventions that contribute to remission will be included in an optimized treatment package, suitable for a large‐scale clinical trial of relapse prevention in AN.
A trait‐based plant economic framework can help increase the value of reforestation for conservation
Authors: Axelsson Erik Petter , Abin Jane Vanessa , T Lardizabal Maria Lourdes , Ilstedt Ulrik , Grady Kevin C. 
Published: April 2022

AbstractWhile reforestation is gaining momentum to moderate climate change via carbon sequestration, there is also an opportunity to use tree planting to confront declining global biodiversity. Where tree species vary in support of diversity, selecting appropriate species for planting could increase conservation effectiveness. We used a common garden experiment in Borneo using 24 native tree species to examine how variation among tree species in their support of beetle diversity is predicted by plant traits associated with “acquisitive” and “conservative” resource acquisition strategies. We evaluate three hypotheses: (1) beetle communities show fidelity to host identity as indicated by variation in abundance and diversity among tree species, (2) the leaf economic spectrum partially explains this variation as shown by beetle preferences for plant species that are predicted by plant traits, and (3) a small number of selected tree species can capture higher beetle species richness than a random tree species community. We found high variation among tree species in supporting three highly intercorrelated metrics of beetle communities: abundance, richness, and Shannon diversity. Variation in support of beetle communities was predicted by plant traits and varied by plant functional groups; within the dipterocarp family, high beetle diversity was predicted by conservative traits such as high wood density and slow growth, and in non‐dipterocarps by the acquisitive traits of high foliar K and rapid growth. Using species accumulation curves and extrapolation to twice the original sample size, we show that 48 tree species were not enough to reach asymptote levels of beetle richness. Nevertheless, species accumulation curves of the six tree species with the highest richness had steeper slopes and supported 33% higher richness than a random community of tree species. Reforestation projects concerned about conservation can benefit by identifying tree species with a disproportional capacity to support biodiversity based on plant traits.
Phenotypes and environment predict seedling survival for seven co‐occurring Great Basin plant taxa growing with invasive grass
Authors: Agneray Alison C. , Parchman Thomas L. , Leger Elizabeth A. 
Published: April 2022

AbstractTrait–environment correlations can arise from local adaptation and can identify genetically and environmentally appropriate seeds for restoration projects. However, anthropogenic changes can disrupt the relationships between traits and fitness. Finding the best seed sources for restoration may rely on describing plant traits adaptive in disturbed and invaded environments, recognizing that while traits may differ among species and functional groups, there may be similarities in the strategies that increase seedling establishment. Focusing on three grass genera, two shrub species, and two forb genera, we collected seeds of all taxa from 16 common sites in the sagebrush steppe of the western United States. We measured seed and seedling characteristics, including seed size, emergence timing, and root and shoot traits, and compiled a suite of environmental variables for each collection site. We described trait–environment associations and asked how traits or environment of origin were associated with seedling survival in invaded gardens. Sampling seven taxa from the same sites allowed us to ask how trait–environment–performance associations differ among taxa and whether natural selection favors similar traits across multiple taxa and functional groups. All taxa showed trait–environment associations consistent with local adaptation, and both environment of origin and phenotypes predicted survival in competitive restoration settings, with some commonalities among taxa. Notably, rapid emergence and larger seeds increased survival for multiple taxa. Environmental factors at collection sites, including lower slopes (especially for grasses), greater mean annual temperatures (especially for shrubs and forbs), and greater precipitation seasonality were frequently associated with increased survival. We noted one collection site with high seedling survival across all seven taxa, suggesting that conditions within some sites may result in selection for traits that increase establishment for multiple species. Thus, choosing native plant sources with the most adaptive traits, along with matching climates, will likely improve the restoration of invaded communities.
Sequential invasions by fruit flies (Diptera: Tephritidae) in Pacific and Indian Ocean islands: A systematic review
Authors: Duyck Pierre‐François , Jourdan Hervé , Mille Christian 
Published: April 2022

AbstractThe aim of our review was to examine the cases of Tephritidae invasions across island systems in order to determine whether they follow a hierarchical mode of invasion. We reviewed the literature on factors and mechanisms driving invasion sequences in Pacific and Southwest Indian Ocean islands and gathered every record of invasion by a polyphagous tephritid in island groups. From invasion date or period, we defined an invasion link when a new fruit fly established on an island where another polyphagous tephritid is already resident (that was indigenous or a previous invader). Across surveyed islands, we documented 67 invasion links, involving 24 tephritid species. All invasion links were directional, i.e., they involved a series of invasions by invaders that were closely related to a resident species but were increasingly more competitive. These sequential establishments of species are driven by interspecific competition between resident and exotic species but are also influenced by history, routes, and flows of commercial exchanges and the bridgehead effect. This information should be used to improve biosecurity measures. Interactions between trade flow, invasive routes, and the presence of invasive and resident species should be integrated into large‐scale studies.
Hypokinetic hypertrophic cardiomyopathy: clinical phenotype, genetics, and prognosis
Authors: Wasserstrum Yishay , Larrañaga‐Moreira José M. , Martinez‐Veira Cristina , Itelman Edward , Lotan Dor , Sabbag Avi , Kuperstein Rafael , Peled Yael , Freimark Dov , Barriales‐Villa Roberto , Arad Michael 
Published: April 2022

AbstractAimsTo describe the phenotype, genetics, and events associated with the development of hypertrophic cardiomyopathy (HCM) with reduced ventricular function (HCMr). Heart failure in HCM is usually associated with preserved ejection fraction, yet some HCM patients develop impaired systolic function that is associated with worse outcomes.Methods and resultsOur registry included 1328 HCM patients from two centres in Spain and Israel. Patients with normal baseline ventricular function were matched, and a competing‐risk analysis was performed to find factors associated with HCMr development. Patient records were reviewed to recognize clinically significant events that occurred closely before the development of HCMr. Genetic data were collected in patients with HCMr. A composite of all‐cause mortality or ventricular assist device (VAD)/heart transplantation was assessed according to ventricular function. Median age was 56, and 34% were female patients. HCMr at evaluation was seen in 37 (2.8%) patients, and 46 (3.5%) developed HCMr during median follow up of 9 years. HCMr was associated with younger age of diagnosis, poor functional class, and ventricular arrhythmia. Atrial fibrillation, pacemaker implantation, and baseline left ventricular ejection fraction (LVEF) of ≤55% were significant predictors of future HCMr development, while LV obstruction predicted a lower risk. Genetic testing performed in 53 HCMr patients, identifying one or more pathogenic variant in 38 (72%): most commonly in myosin binding protein C (n = 20). Six of these patients had an additional pathogenic variant in one of the sarcomere genes. Patients with baseline HCMr had a higher risk (hazard ratio 6.4, 4.1–10.1) for the composite outcome and for the individual components. Patients who developed HCMr in the course of the study had similar mortality but a higher rate of VAD/heart transplantation compared with HCM with normal LVEF.ConclusionsHypertrophic cardiomyopathy with reduced ejection fraction is associated with heart failure and poor outcome. Arrhythmia, cardiac surgery, and device implantation were commonly documented prior to HCMr development, suggesting they may be either a trigger or the result of adverse remodelling. Future studies should focus on prediction and prevention of HCMr.
The economic value of grassland ecosystem services: A global meta‐analysis
Authors: Liu Huifang , Hou Lingling , Kang Nannan , Nan Zhibiao , Huang Jikun 
Published: April 2022

AbstractBackgroundGrasslands provide a wide variety of ecosystem services that contribute to human wellbeing. While an increasing number of studies are evaluating the monetary value of grassland ecosystem services, most of them focus on specific grassland ecosystem services at regional or local scales, and they use different assessment methods.MethodsThis paper provides a comprehensive assessment of the economic value of global grassland ecosystem services based on a meta‐analysis of 702 observations from 134 primary studies.ResultsThe economic values of different ecosystem services cover a wide range of grassland types, regions, and estimation methods. The annual economic value per hectare ranges from $3955 for semidesert grasslands to $5466 for tropical grasslands. On average, regulating services have the highest value, which is approximately four times that of provisioning services or approximately eight times that of food supply services. Several factors impact the estimated ecosystem service values, including the evaluation method, source and year of publication, and study site. The results indicate that the annual economic value of global grasslands exceeds $20.8 trillion.ConclusionsThe findings of this study not only provide useful information for understanding the economic value of various ecosystem services associated with different types of grasslands but also have important policy implications for the ecological conservation of grassland globally.