bluuebunny/crossref_metadata_2025_split huggingface dataset:
Organizational agility to counter coronavirus implications in emerging Saudi universities
Authors: Alharbi Gasem Aail 
Published: January 2022

Objective: The study's primary goal was to uncover the reality of organizational agility in emerging universities. It also aimed to determine the statistical variances between the mean scores of the sample used in the axes of the organizational agility questionnaire for these universities. The main variables used are gender, academic position, and years of experience. Methodology: The study utilized the descriptive method. The data collection process entailed handing out questionnaires to a sample of seven hundred and forty-seven faculty members in Jazan, Bishah, Hafar Al-Batin, Shaqraa, and Najran Universities. Results: Emerging universities regularly practice organizational agility in light of the emerging coronavirus with high flexibility at moderate costs. The study's results also indicated mathematically substantial variances at the degree of viability between the male sample's average and the female sample's average in favor of the female sample in the timing and the flexibility of practices. It also indicated statistically significant variances at the degree of significance between the mean scores of the research sample, attributed to the difference in the academic position in the timing, flexibility, and cost of practices.
Keywords: Coronavirus, Degree of variability Emerging universities, Organizational agility, Strategy,
The contribution of psychological barriers in predicting the cognitive load among the university students’ users of blackboard system
Authors: Abdellatif Mohamed Sayed , Abdul-Gawad Mervat Azmy Zaki 
Published: January 2022

Psychological barriers are one of the most common problems facing individuals nowadays due to everyday life pressures. The current research aimed at identifying the extent to which psychological barriers contribute to predicting the perceived cognitive load of blackboard e-learning management system users. The research sample comprised (240) male and female among the University Students. The descriptive-analytical approach, specifically the predictive correlative research method was utilized to reveal the relationship between the research variables. The research main results revealed that there was a statistically significant correlative positive relationship between the psychological barriers and the cognitive load (intrinsic, extraneous, and the overall degree), and there was no statistically correlative relationship between psychological barriers and the Germane cognitive load. Besides, results concluded that the external psychological barriers were better at predicting the overall degree of the perceived cognitive load. Psychological barriers and cognitive load must be considered within the e-learning settings through making use of the results of the current study in developing training and counseling programs to reduce the students' psychological barriers and cognitive load levels.

Keywords: psychological barriers; cognitive load; Blackboard system
Academic procrastination' relation to undesirable behaviours among faculty members from the students' perspective
Authors: Samawi Fadi S. , Alramamna Asri A. , Alkhatib Bilal A. , Alghafary Nedal A. 
Published: January 2022

Background: Academic procrastination had been reported widely to be in association with unwanted behaviours among university students. However, this association was not studied extensively in higher educational institutions. Aim: This research aimed to measure the level of academic procrastination among college students and the unwanted behaviours among faculty members from students' viewpoints. Method: The research sample consisted of 430 students randomly selected for the summer semester 2016/2017 using the descriptive correlation approach. An instrument to measure academic procrastination was developed to achieve the aims of the research. Results: The findings indicated that the level of academic procrastination was medium, whereas unwanted behaviours were high. The findings result showed a negative association between academic procrastination and unwanted behaviours. One of the most dimensions of unwanted behaviours that forecasted academic procrastination is the dimension of managing and organising classrooms.
Keywords: Academic procrastination; educational psychology; descriptive approach; university students/Jordan; unwanted
behaviours.
Features of the training process of freestyle wrestlers in the pre-competition stage
Authors: Konakbayev Bakytbek , Bekembetova Raisa , Bekturganov Omirzhan 
Published: January 2022

As a kind of sport, wrestling is characterized by a complex compositional nature of preparing, which requires equal attention to the development of the physical and functional qualities of an athlete. The aim of the study is to optimize the mode and algorithm of training loads of a competitive nature in the period of preparation. The effectiveness of the training process was evaluated by functional indices and blood lactate level not only at the end of training load, but also in the recovery period. In the process of the study also, pedagogical analysis was carried out, anthropometric parameters and analysis of body components were determined. The results of the study indicate the need for regular monitoring of the regime of loads in order to timely correction of the training process, taking into account the individual characteristics of wrestlers at the stage of pre-competition preparing.
Keywords: competitive wrestling; freestyle wrestling; functional preparation; lactate; training process.
Local wisdom-based character education for special needs students in inclusive elementary schools
Authors: Ibnu Syamsi , Tahar Mohd. Muchtor 
Published: January 2022

The research aims to describe how local wisdom can be orchestrated in the well-implemented character education for inclusive elementary schools (ESs). A total of 50 teachers and 200 students from 50 inclusive ESs in four districts and one municipality in Indonesia participated in the study. The data, collected by conducting interviews, observation, and documentation, were analyzed by means of qualitative descriptive techniques. There were three major themes identified. Students preferred traditional games as their favorite means of learning. Togetherness in team-based games encouraged the students to see their special needs differences as normal. Furthermore, the accessibility of the traditional games’ tools empowered the students. These findings suggest that traditional children’s games are to be elaborated and used to support the local wisdom-based character education in the inclusive ESs, and teachers are to initiate and develop the use of various locally originated children’s games to enhance character education.

Keywords: character education, local wisdom, special needs
Total edge irregularity strength of some cycle related graphs
Authors: Rajendran Ramalakshmi , KM Kathiresan 
Published: January 2022

<p>An edge irregular total <em>k</em>-labeling <em>f</em> : <em>V</em> ∪ <em>E</em> → 1,2, ..., <em>k</em> of a graph <em>G</em> = (<em>V,E</em>) is a labeling of vertices and edges of <em>G</em> in such a way that for any two different edges <em>uv</em> and <em>u'v'</em>, their weights <em>f</em>(<em>u</em>)+<em>f</em>(<em>uv</em>)+<em>f</em>(<em>v</em>) and <em>f</em>(<em>u'</em>)+<em>f</em>(<em>u'v'</em>)+<em>f</em>(<em>v'</em>) are distinct. The total edge irregularity strength tes(<em>G</em>) is defined as the minimum <em>k</em> for which the graph <em>G</em> has an edge irregular total <em>k</em>-labeling. In this paper, we determine the total edge irregularity strength of new classes of graphs <em>C<sub>m</sub></em> @ <em>C<sub>n</sub></em>, <em>P<sub>m,n</sub></em>* and <em>C<sub>m,n</sub></em>* and hence we extend the validity of the conjecture tes(<em>G</em>) = max {⌈|<em>E</em>(<em>G</em>)|+2)/3⌉, ⌈(Δ(<em>G</em>)+1)/2⌉}<em> </em> for some more graphs.</p>
Relationship between adjacency and distance matrix of graph of diameter two
Authors: Chasanah Siti L. , Khairunnisa Elvi , Yusuf Muhammad , Sugeng Kiki A. 
Published: January 2022

The relationship among every pair of vertices in a graph can be represented as a matrix, such as in adjacency matrix and distance matrix. Both adjacency and distance matrices have the same property. Adjacency and distance matrices are both symmetric matrix with diagonals entries equals to 0. In this paper, we discuss relationships between adjacency matrix and distance matrix of a graph of diameter two, which is <em>D=2(J-I)-A</em>. From this relationship, we also determine the value of the determinant matrix <em>A+D</em> and the upper bound of determinant of matrix <em>D</em>.
On local antimagic vertex coloring of corona products related to friendship and fan graph
Authors: Himami Zein Rasyid , Silaban Denny Riama 
Published: January 2022

Let <em>G</em>=(<em>V</em>,<em>E</em>) be connected graph. A bijection <em>f </em>: <em>E</em> → {1,2,3,..., |<em>E</em>|} is a local antimagic of <em>G</em> if any adjacent vertices <em>u,v</em> ∈ <em>V</em> satisfies <em>w</em>(<em>u</em>)≠ <em>w</em>(<em>v</em>), where <em>w</em>(<em>u</em>)=∑<sub>e∈E(u) </sub><em>f</em>(<em>e</em>), <em>E</em>(<em>u</em>) is the set of edges incident to <em>u</em>. When vertex <em>u</em> is assigned the color <em>w</em>(<em>u</em>), we called it a local antimagic vertex coloring of <em>G</em>. A local antimagic chromatic number of <em>G</em>, denoted by <em>χ</em><sub>la</sub>(<em>G</em>), is the minimum number of colors taken over all colorings induced by the local antimagic labeling of <em>G</em>. In this paper, we determine the local antimagic chromatic number of corona product of friendship and fan with null graph on <em>m</em> vertices, namely, <em>χ</em><sub>la</sub>(<em>F</em><sub>n</sub> ⊙ \overline{K_m}) and <em>χ</em><sub>la</sub>(<em>f</em><sub>(1,n)</sub> ⊙ \overline{K_m}).
Sebaceous Carcinoma of the Vulva: An Unexpected Diagnosis and Literature Review
Authors: Rocha Ana Carolina , Sá Maria Inês , Abrantes Carlos , Sousa Rita 
Published: January 2022

Sebaceous carcinoma of the vulva is a rare malignancy of the sebaceous glands, with potentially aggressive behaviour, that is usually found in the peri-ocular area. Nonetheless, there are sebaceous glands in the vulva and this diagnosis is especially rare, with only ten cases described in the literature. We report a case of 78-year-old female patient who presented with vulvar pruritus, previously treated with topical steroid and antifungal treatments, without improvement. The vulvar examination showed a visible yellow papule, 12 x 10 mm on the right major labia, which was biopsied and the microscopic examination revealed an invasive sebaceous carcinoma of the vulva, with an in situ component. We performed an uneventful excisional biopsy, followed by a subsequent margin widening. Three months after the diagnosis, she presented with the first recurrence. Two and half years after the diagnosis, she recurred with a larger lesion (13 mm) in the upper half of small right lip, more than 10 mm away from the midline. In a multidisciplinary meeting it was decided that the patient should undergo partial right vulvectomy with homolateral inguino-femoral sentinel node biopsy (one negative node). There was no evidence of recurrence one-year post-surgery.
Treatment of Overweight and Obesity by Suppressing Intestinal Epithelial Renewal in a Mouse Model of Obesity
Authors: Zeng Wei-ping 
Published: January 2022

Abstract
Obesity and overweight pose serious risk for many diseases and clinical conditions.However currently available weight loss strategies and pharmacotherapies of obesity are notsatisfactory. This study shows that treatments with pH modifiers such as acids are not only welltolerated by obese mice but also very effective in reducing bodyweight and fat mass by depletingand suppressing the proliferation of proliferating epithelial cells of the intestinal villi. Thereforeother cell proliferation inhibitors that suppress intestinal epithelial renewal can also be used forpharmacotherapy of obesity and overweight.
Reduction of Pulmonary Inflammation by pH Modifiers
Authors: Zeng Wei-ping 
Published: January 2022

Abstract
Pulmonary inflammation is a common pathological feature of a variety of diseases, ofwhich successful therapy with currently available anti-inflammatory drugs is limited byresistance and adverse side effects. Using the ovalbumin-induced mouse allergic asthma model,the present study shows that treatments with pH modifiers, particularly simple acids such asacetate or hydrochloric acid, effectively depleted inflammatory cells in the lungs and blood aswell as hyperplastic lung tissue cells while preserving the structure of the blood vessels and lungparenchyma. The acid treatments also suppressed mucus hypersecretion. These resultsdemonstrated pH modifiers as a new class of broad-spectrum anti-inflammatory agents with antiproliferationand mucus suppression activities.
Understanding of Controllable Optical Memory Using 1D Inp Based Photonic Structures at Three Communication Windows
Authors: M Rajesh Khanna , Appathurai Karthikeyan , G Kuppusamy P , R Prianka R 
Published: January 2022

Abstract
The present research realises a controllable optical memory using one dimensional indium phosphate (InP) photonic structures at three optical communication windows (850 nm, 1310 nm and 1550 nm). The photonic structures comprise 21 layers of InP and air material. The memory applications are realised at both single and dual signals of the communication windows. The physics of the research deals with the materials property including the variation of the refractive indices with respect to the input signal. Similarly, mathematics of the works relies on the analysis of reflectance, transmittance and absorbance phenomena. Further, the light from visible spectrum acts as triggering signal to realise optical memory applications. Finally, it is revealed that InP based photonic structures are suitable for controllable memory applications pertaining to the single wavelength (850 nm, 1310 nm, 1550 nm) or dual wavelengths (850 nm and 1310 nm, 1310 nm and 1550 nm, 1550 nm and 850 nm).
Pediatric Resident Education in Pediatric Cardiology – A Needs Assessment
Authors: Hovis Ian W. , Frank Lowell H. , Gordish-Dressman Heather , Spurney Christopher F. 
Published: January 2022

Abstract
Background: Although congenital heart disease is the most common human birth defect, the scope and breadth of pediatric cardiology is far more diverse. Additionally, there continues to be rapid advancements in the field with educators becoming increasingly sub-specialized. As such, determining the topics general pediatric residents are taught must be selected based on numerous factors including resident career goals, core topics for board exams, and educator preferences. This study aimed to determine if the educational needs of general pediatric residents are met while on a pediatric cardiology rotation. Methods: All PL-2 and PL-3 residents in the Children’s National Hospital pediatrics residency program who had completed a required cardiology rotation as well as all pediatric cardiology fellows and pediatric cardiology attendings were asked to complete a survey. Participation in the study was voluntary. Respondents were asked to answer questions related to the perceived effectiveness and applicability of the currently administered cardiology curriculum, specifically inquiring about methods of teaching, the level taught, and the utility of topics selected. Results: Twenty-four (31%) of the 77 eligible residents completed the survey. Fourteen (82%) of the eligible attendings and nine (75%) of the cardiology fellows completed the survey. Seventeen unique topics in pediatric cardiology were ranked. The highest rated topics based on both perceived needs and wants included congenital heart disease, murmurs, cardiac physiology, ECG interpretation, and syncope/dizziness. Participants reported the highest satisfaction for whiteboard and bedside teaching. Conclusions: Overall, general pediatrics residents were satisfied with the current educational design of the inpatient cardiology rotation. These data provide a framework, both in teaching modalities and core concepts, for continued development and reassessment of inpatient pediatric cardiology rotations to optimally prepare pediatric residents with a strong foundation in pediatric cardiology.
Clinical and Pathological Features of Immune-Mediated Necrotising Myopathies in a Single-Centre Muscle Biopsy Cohort
Authors: Yang Hongxia , Tian Xiaolan , Zhang Lining , Li Wenli , Liu Qingyan , Jiang Wei , Peng Qinglin , Wang Guochun , Lu Xin 
Published: January 2022

Abstract
Objective

Immune-mediated necrotising myopathy (IMNM) is a recently entitled novel subset of idiopathic inflammatory myopathies (IIM) characterized by significant elevated creatine kinase (CK) level, muscle weakness and predominant muscle fibre necrosis in muscle biopsy. This study aimed to investigate the clinical and pathological characteristics of patients with IMNM in our single-centre muscle biopsy cohort.
Methods

A total of 860 patients who had muscle biopsy reports in our centre from May 2008 to December 2017 were enrolled in this study. IMNM was diagnosed in according with 2018 European Neuromuscular Centre (ENMC) clinicopathological diagnostic criteria for IMNM.
Results

The muscle biopsy cohort consisted of 531 patients with IIM (61.7%), 253 patients with non-IIM (29.4%), and 76 undiagnosed patients (8.8%). Among IIM patients, polymyositis (PM), dermatomyositis(DM), amyopathic dermatomyositis, juvenile DM, and inclusion body myositis were 182(21.2%), 236(27.4%), 83(9.7%), 18(2.1%) and 3(0.3%), respectively. In PM subgroup, 59 patients met serological and pathological characteristics of IMNM according to 2018 ENMC criteria including 29 anti-SRP-positive patients,10 anti-HMGCR-positive patients and 20 MSA-negative patients. Limb girdle muscular dystrophy (LGMD) 2B and lipid storage myopathy (LSM) were 29 and 16 respectively, which present similar manifestations of IMNM with elevated CK levels and muscle weakness among non-IIM group. IMNM patients had older age of onset (mean: 42.25 vs 21.66 and 24.56, p<0.0001), shorter duration of diseases (mean: 22.56 vs 66.69 and 48.94, p<0.0001) and more frequent of dysphagia (33.9% vs 3.4% and 6.3%, p<0.0001) compare to patients with LGMD 2B and LSM. Muscle biopsy from IMNM patients showed frequent muscle fibre necrosis (96.6% vs 72.4% and 56.3%, p<0.0001), overexpression of MHC-I on sarcolemma (81.4% vs 37.9% and 12.9%, p<0.0001) and CD4+ T cell endomysial infiltration (89.9% vs 53.6% and 50%, p<0.0001) compared with LGMD 2B and LSM patients.
Conclusions

It is easy to distinguish IMNM from other subtype of IIM according to clinical symptoms and MSAs profiles. However, distinguishing IMNM from disorders clinically similar non-IIM need to combine with clinical, serological and pathological features.
Erythemal UV Dose and UV Index Measurement at 37th North Latitude and Its Possible Effects on Humans
Authors: Emrahoglu Nuri 
Published: January 2022

Abstract
In this study, UV irradiance and UV erythemal and UV index data of May, June, July and August measured in Adana (longitute=36 E, latitute=37 N altitute=140m) between 2013 and 2019 were analyzed. As a result of the analysis, the average of four months was 14.16 MED (2.9736 J/m2) and the highest value of these four months was calculated as 15.6 MED (3.276 J/m2) in July. The percentage frequency of the total daily UV dose was also calculated and it was determined that the region was under the effect of 70-80% high UV dose. In addition, it was calculated to have a high UV index according to local time (10.00-14.00). It was concluded that this situation poses a great risk for workers working in agricultural areas in the region and for people who spend their summer holidays by the sea. UV Dose-Ozone, UV Dose-temperature, UV Dose-humidity and Ozone-temperature correlations were also calculated. As a result of the comparison, it was found that there was an R= -0.64 correlation between UV-ozone, an R= -1.00 correlation between temperature and ozone, and a direct correlation of R= 0.60 between UV radiation and temperature.
Significance of HMMR Overexpression in Hepatocellular Carcinoma
Authors: Zhao Weidong , Zhang Zhengxiang 
Published: January 2022

Abstract
Background: Hyaluronan Mediated Motility Receptor (HMMR), as one of the key surface binding proteins of HA, is up-regulated in many tumors. What’s more, the expression level of HMMR is usually correlate with tumor progression and prognosis. However, the relationship between the expression of HMMR and the prognosis and immune infiltration of hepatocellular carcinoma (HCC) is still unclear.Methods: We analyzed the expression level of HMMR by TIMER database, GEO database and GEPIA database. The correlation between the HMMR expression and tumor prognosis was analyzed via the Kaplan-Meier plots. The TIMER database and GEPIA database were used to study the relationship between HMMR expression and immune infiltration. GO and KEGG enrichment analysis were used to explore the potential biological functions of HMMR.Results: HMMR expression was significantly higher in several human cancers, including HCC, than in corresponding normal tissues. High HMMR expression associated with poorer overall survival, disease-specific survival, progression-free survival and relapse-free survival in HCC patients. HMMR showed strong correlation with tumor-infiltrating B cells, CD4 + and CD8 + T cells, macrophages, neutrophils, and dendritic cells. Several immune marker genes expression, including CD86, IRF5, CD11b, KIRIDL4, CD11c, IFN-γ, STAT3, STAT5B, and CTLA4, have markedly positive correlations with HMMR expression. Enrichment analysis found that HMMR is mainly involved in cell cycle, DNA replication and repair, PLK1 pathway, E2F pathway, ATR pathway and AURORA B pathway.Conclusions: HMMR is a potential prognostic biomarker that influence tumor progression and correlated with tumor immune cells infiltration in HCC.
Blood Transfusion Has An Adverse Impact On The Prognosis of Patients Receiving Chemotherapy For Advanced Colorectal Cancer: Experience From a Single Institution With a Patient Blood Management Program
Authors: Lim Ah Reum , Kim Jwa Hoon , Hyun Myung Han , Chang Won-Jin , Lee Soohyeon , Kim Yeul Hong , Park Kyong Hwa , Park Jong Hoon 
Published: January 2022

Abstract
Purpose: Perioperative blood transfusion in early stage cancer patients had a negative effect on the prognosis of patients, but the prognostic impact of transfusion in advanced cancer patients remains unclear. To minimize transfusion, a institutional patient blood management (PBM) program was launched, and we evaluated the new program has changed practice and impacted on prognosis of advanced cancer patients. Methods: We investigated the medical records of colorectal cancer patients who received chemotherapy from 2015 to 2020. The amount and frequency of transfusion, iron replacement and laboratory findings, and overall survival were compared before and after implementation of PBM. Results: The rate of transfusion in colorectal cancer patients was significantly decreased from 23.5/100 person-quarter in 2015 to 1.2/100 person-quarter in 2020, but iron supplementation therapy was frequently used and the proportion of patients who received transfusion under haemoglobin 7 g/dL significantly increased from 15.9% in 2015 to 55.3% in 2020. Multivariate analysis revealed that transfusion was a significant risk factor affecting the overall survival of patients (HR 2.70, 95% CI: 1.93–3.78, p<0.001). Kaplan–Meier analysis revealed that overall survival was significantly longer in non-transfused patients than in transfused patients (11.0 versus 22.4 months; HR 0.69, 95% CI: 0.56–0.86, p<0.001). Conclusions: This study shows that minimized transfusion through an institutional PBM can positively affect the prognosis of patients who are receiving chemotherapy for advanced colorectal cancer.