bluuebunny/crossref_metadata_2025_split huggingface dataset:
Outcomes of early vitrectomy for endophthalmitis after cataract surgery in delta population, Egypt, 2015–2020
Authors: Tabl Ahmed A. , Masoud Mohamed G. , Abdelhalim Gehad H. , Tabl Marwa A. 
Published: July 2022

Purpose
To evaluate the outcomes of early pars-plana vitrectomy (PPV) in the management of acute onset endophthalmitis after cataract surgery.

Study design
Retrospective observational study.

Patients and methods
We collected data from 11 patients who were diagnosed as acute infectious endophthalmitis within 6 weeks after cataract surgery, from January 2015 to December 2020 and had undergone early 23-G PPV and were followed up for 3 months. We analyzed factors that may affect prognosis and final visual outcomes.

Results
The mean age was 58±5 years, there was male predominance (72.7%). The mean axial length was 24.76±1.58 mm. The baseline best-corrected visual acuity was 2.3 logMAR and was improved to 1.2 logMAR at the third month (P<0.001). Mixed air/fluid intraocular tamponade was used in 63.6% of patients. About half of the cases had positive cultures (54.5%), and the most frequent organism was Staphylococcus aureus (66.7%). Retinal detachment was reported in 36.4% of patients. The preoperative factors correlated with final best-corrected visual acuity were posterior vitreous detachment and intraocular tamponade.

Conclusions
Early PPV for acute-onset endophthalmitis after cataract surgery aided in improving final visual outcome and preserving structural and functional integrity of the globe, thus preventing late complications that could affect patients’ quality of life. Factors that influence the final visual outcome were intraocular tamponade and posterior vitreous detachment.
Evaluation of the efficacy of high-fluence corneal collagen cross-linking in fusarium corneal ulcer in rabbits
Authors: Elbassiouny Ramy A.M. , Ghaith Alaa A. , Farhad Hafezi , Baddour Manal M. , Eman Sheta , Elmassry Ahmed A. 
Published: July 2022

Background
Accelerated photoactivated chromophore for keratitis–corneal collagen cross-linking (PACK-CXL) was investigated to be effective in the treatment of fungal keratitis in many studies. High-fluence CXL was used effectively in the treatment of progressive keratoconus but not tested in PACK-CXL for fungal infection.

Aim
To evaluate the antifungal efficacy of high-fluence CXL in the treatment of induced fusarium corneal ulcer in rabbits.

Design
This is an experimental interventional study.

Patients and methods
This is an experimental interventional study conducted on 16 eyes of eight rabbits for which fusarium corneal infection was induced by intrastromal corneal injection. The rabbits were divided into two groups: group A received no treatment and was left as a control group. Group B received a single high-fluence PACK-CXL session. All rabbits were followed up for 6 days and then the eyes were enucleated. Culture was performed for seven corneas and histopathology for the remaining cornea.

Results
There was statistically significant deterioration in group A (P=0.003), while a statistically significant clinical improvement was seen in group B (P<0.001). The median colony-forming units was more in group A (4×104) than in group B (2×102). Histopathological examination also revealed less inflammatory signs in high-fluence PACK-CXL-treated group.

Conclusions
High-fluence PACK-CXL total ultraviolet A fluence of 7.2 J/cm2 is effective in the treatment of mycotic keratitis.
Target Specific Uptake of a Newly Synthesized Radiolabeled 5α-Reductase Inhibitor “Tc-99m-17-Oxo-17a-Aza-D-Homo-5-Androsten-3β-yl Phenoxyacetate (Tc-99m-17a-Aza Steroid)” in Rat Prostatic Neoplastic Lesions
Authors: Jan Gowsia , Bhat Swati , Chauhan Monika , Dhawan Devinder Kumar , Dhingra Neelima , Chadha Vijayta Dani 
Published: July 2022

Objective:
Considering the 5α-reductase (5AR) inhibitory activity of the oximes and the importance of the ester group in increasing the anti-androgenic property, we reasoned to synthesize a compound having a lactam group in ring D and an ester group at the 3 β position of the androsterone nucleus. The study aims to radiolabel 17-oxo-17a-aza-D-homo-5-androsten-3β-yl phenoxyacetate (17a-aza steroid) with Tc-99m to evaluate its targeted uptake in experimentally induced prostate carcinogenesis in rats.

Materials and Methods:
The prediction of the optimal interaction and binding affinity of Tc-99m-17-oxo-17a-aza-D-homo-5-androsten-3 β-ylphenoxyacetate (Tc-99m-17a-aza steroid) toward 5AR inhibitor was done using Biopredicta Vlife MDS tool. Tc-99m-17a-aza steroid was developed by direct radiolabeling protocol. The radio-pharmacological characteristics (serum stability, plasma protein-binding ability, and lipophilicity) of the complex were evaluated. Further, the bio-distribution studies of the complex were performed in rats with experimentally induced prostate carcinogenesis.

Results:
The in-silico analysis exhibits favorable binding of Tc-99m-17a-aza toward 5AR with D score-130.97. The radiochemical purity of Tc-99m-17a-aza was 96.79%. The radio-complex maintained stability in the rat serum for a period of 6 h (hours). Plasma protein binding and Log Po/w value were observed to be 86.23 ± 7.08% and 0.118 ± 0.045, respectively. A significantly enhanced percent-specific uptake was observed in the prostate of rats with induced prostate carcinogenesis.

Conclusion:
The study concludes that Tc-99m-17a-aza exhibits prostate specificity and can be explored further for its potential as a radionuclide imaging probe.
Evaluation of Reconstruction Algorithms to Validate the NEMA Phantom Results in Clinical Scenario – A Comparative Study Using Time-of-Flight versus Non-Time-of-Flight Positron Emission Tomography Imaging
Authors: Kumar Ajay , Jacob Pearl , Watts Ankit , Joseph Anwin , Kaur Harneet , Hooda Monika , Kaur Amritjyot , Singh Baljinder 
Published: July 2022

Objectives:
The objective is to standardize the reconstruction parameters for the time-of-flight (TOF) versus non-TOF positron-emission tomography/computed tomography (PET/CT) imaging data and validation of the same in a clinical setting.

Methods:
The four spheres (10.0/13.0/17.0/22.0 mm) of the PET phantom (NEMA IQ Nu 2-2001) were filled with four times higher activity of [18F]-NaF than the background (5.3kBq/mL). Imaging (image matrix – 128 × 128 × 47, 2 min, 3D model) was done using two different (TOF/non-TOF) PET scanners. Phantom data were reconstructed in TOF and non-TOF modes for lutetium–yttrium oxyorthosilicate and non-TOF mode for bismuth germanate-based PET scanners. The reconstructed data (by varying iteration and subsets) that provided the best image contrast and signal-to-noise ratio (SNR) were evaluated. The whole-body [18F]-fludeoxyglucose (FDG) PET/CT scans (7–8 frames; 2.0 min/frame) in 16 lymphoma patients were acquired at 60 min after injecting the radioactivity (370.0–444.0 MBq of [18F]-FDG. The clinical PET/CT data were reconstructed using phantom-derived reconstruction parameters and evaluated for image contrast and SNR of the detected lesions.

Results:
TOF reconstruction at second iteration provided significantly (P ≤ 0.02) higher SNR (20.7) and contrast (contrast recovery coefficient/background variability = 3.21) for the smallest hot lesions (10.0 mm) in the phantom than the non-TOF system. Similarly, in patient data analysis for the selected FDG avid lesions, the SNR values were significantly (P = 0.02) higher (13.3 ± 6.49) in TOF than (11 ± 6.48) in non-TOF system. Further, the small (≤10.0 mm) lesions were seen more distinctly in TOF system.

Conclusion:
It is thus observed that TOF reconstruction converged faster than the non-TOF, and the applicability of the same may impact the image quality and interpretation in the clinical PET data. The validation of the phantom-based experimental reconstruction parameters to clinical PET imaging data is highly warranted.
Role of 18-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography in Predicting Residual Disease Posttreatment Completion in Retinoblastoma Patients
Authors: Moothedath Abdul Wajid , Chopra Kanwaljeet Kaur , Seth Rachna , Meena Jagdish Prasad , Gupta Aditya Kumar , Kumar Rakesh , Jana Manisha , ArunRaj Sreedharan Thankarajan 
Published: July 2022

Background:
Retinoblastoma (RB) is the most common primary intraocular malignancy of childhood. Magnetic resonance imaging (MRI) of the orbit and brain is the preferred imaging modality to diagnose and define extent of disease as well as to assess response to therapy. Sometimes, it may be difficult to differentiate the presence of active residual disease from therapy-related changes based on posttreatment completion MRI.

Materials and Methods:
RB patients who completed treatment between January 2017 and October 2019 were retrospectively analyzed. We evaluated the utility of F-18-fluorodeoxyglucose (FDG) positron emission tomography-computed tomography (PET-CT) to predict active disease in RB patients who continued to have residual disease on MRI at completion of treatment.

Results:
Out of the 89 patients who completed treatment, dilemma regarding remission status was present in 11 children. All 11 patients underwent FDG-PET-CT. None of them had evidence of metabolically active disease in the orbit, optic nerve, brain, or rest of the body. After a median follow-up of 24 months, no children developed any evidence of disease progression in the form of local or distant relapse.

Conclusion:
Our results showed that in MRI doubtful cases, a nonavid FDG-PET is reassuring in avoiding further therapy as long as close follow-up can be ensured. FDG-PET-CT may emerge as a useful functional modality to predict disease activity in RB.
Knowledge, Attitude, and Practice of Family Medicine Residents Toward COVID-19 in Riyadh, Saudi Arabia
Authors: Altraif Sara I. , Almezaini Lamees I. , Alsaif Hadeel K. , Altraif Ibrahim H. 
Published: July 2022

Objectives:
The aim is to evaluate the knowledge, attitude, and practice (KAP) regarding prevention, diagnosis, and management of COVID-19 in family medicine residents in Riyadh, Saudi Arabia and also to examine the association of the residents' demographic variables with their COVID-19 KAP level.

Methods:
A cross-sectional survey conducted during July to August 2020 that targeted all family medicine residents who were enrolled in the Saudi board training programs in Riyadh. An online version of a specifically designed questionnaire was distributed to determine the residents' KAP toward COVID-19.

Results:
A total of 97 of 170 residents responded for a response rate of 57%. The most important results noted from this study are that participants had satisfactory knowledge of COVID-19; but, it was not associated with their demographic characteristics. Most participants demonstrated positive attitudes toward persons having risk factors for COVID-19 and who disclose their exposure (n = 82, 85%). Most participants exhibited good practices except participating in training programs concerning COVID-19 infection prevention and control (n = 46, 47%). Total knowledge scores were significantly affected by feeling tired, lack of confidence in defeating the virus, and persons with risk of COVID-19 infection. There was no significant association between the knowledge and practice.

Conclusion:
The results demonstrated that family medicine residents in Riyadh overall had good KAP on COVID-19 disease in Riyadh, Saudi Arabia. Such good KAP could help limit viral spread.
Depression, Anxiety, and Stress among the Community during COVID-19 Lockdown in Saudi Arabia
Authors: Alshammari Sulaiman A. , Alotaibi Razan Sultan , Almajed Ashwaq Ali , Omar Thikrayat Abdulhafeeth 
Published: July 2022

Objectives:
(1) We aimed to measure the levels of depression, anxiety, and stress among the Saudi population during COVID-19 lockdown and their association with different personal characteristics. (2) The secondary aims included assessing the perceived social and physical impacts of COVID-19 lockdown on individuals and the different coping strategy practices during this tough period.

Methods:
A cross-sectional study was conducted between May and June 2020 in Saudi Arabia. We collected data from both sexes aged 18 years and older using social media. The online questionnaire collected data on their sociodemographic, physical, and social conditions, and the presence and control of chronic diseases as well as their evaluation according to the Depression, Anxiety, and Stress Scale-21.

Results:
Of the 878 participants, 56.6% were female, 54.6% were aged between 35 and below, 52.6% were married, and 97.4% had a secondary school and above. Approximately a quarter of the participants or relatives had been diagnosed with COVID-19. Moderate-to-severe depression, anxiety, and stress were reported in 32.6%, 28.7%, and 22.6% of the participants, respectively. The younger than 35 years, unmarried, not working, and the previous diagnosis of COVID-19 were associated with higher scores of depression, anxiety, and stress. In addition, the participants reported several coping strategies such as doing physical exercise, hobbies, chatting over social media, watching TV/movies, playing electronic games, increasing religious prayers, and getting psychosocial help.

Conclusion:
A quarter of the participants reported a moderate-to-severe psychological impact. They adopted various strategies to reduce the adverse lockdown effect. In a future pandemic, health-care providers and policymakers can focus on potential risk factors and coping strategies to prevent, intervene early, and treat sufferers.
Evaluation of the Use of Electronic Growth Charts Customized for Race and National Values
Authors: Jamal Amr A. , AlHokair Abdullah A. , Temsah Mohamad-Hani A. , Alsohime Fahad , Al-Eyadhy Ayman A. , El-Mouzan Mohamad , Tharkar Shabana 
Published: July 2022

Background:
As compared with traditional paper-based charts, population-specific Saudi Growth Charts (SGC) integrated into electronic health records offer several functionalities. However, few studies have explored clinicians' perceptions and practices related to the recording of growth parameters as they adapt to the electronic methods.

Objective:
The objective of this study is to estimate clinicians' use of the recently adapted electronic SGC versus other known electronic international growth charts.

Methods:
This cross-sectional survey was performed on 116 pediatricians serving at the university medical center. An online questionnaire that included the types of growth charts used, clinicians' confidence level with the electronic interface, and documentation practices for children's growth parameters was uploaded using the SurveyMonkey® platform, and participants were invited to participate through an e-mailed link. Data were analyzed using the IBM software Statistical Package for the Social Sciences version 22.0. (SPSS Inc., Chicago, IL, USA) for Windows®.

Results:
Most of the pediatricians (76.7%) reported using electronic-based growth charts in preference to paper-based charts, whereas 17.3% preferred using both. Seventy-five percent agreed that the SGC can accurately diagnose underweight Saudi infants and children, as compared with 56% for the World Health Organization and 44% for the Centers for Disease Control and Prevention growth charts. Height, weight (body mass index), and nutritional status were the most documented parameters. Multivariate linear regression analysis showed physicians with longer experience in pediatric clinical practice years demonstrated lesser documentation of growth parameters. In addition, physicians caring for more number of children per week were more likely to frequently document growth parameters (P = 0.003).

Conclusion:
The integration and implementation of the electronic version of SGC have been encouraging, and the SGC shows promising results in recording child growth parameters for Saudi children with minimum discrepancies in interpretation as compared to the other international growth charts.
Two problems on random analytic functions in Fock spaces
Authors: Fang Xiang , Tien Pham Trong 
Published: July 2022

AbstractLet
$f(z)=\sum _{n=0}^\infty a_n z^n$
be an entire function on the complex plane, and let
${\mathcal R} f(z) = \sum _{n=0}^\infty a_n X_n z^n$
be its randomization induced by a standard sequence
$(X_n)_n$
of independent Bernoulli, Steinhaus, or Gaussian random variables. In this paper, we characterize those functions
$f(z)$
such that
${\mathcal R} f(z)$
is almost surely in the Fock space
${\mathcal F}_{\alpha }^p$
for any
$p, \alpha \in (0,\infty )$
. Then such a characterization, together with embedding theorems which are of independent interests, is used to obtain a Littlewood-type theorem, also known as regularity improvement under randomization within the scale of Fock spaces. Other results obtained in this paper include: (a) a characterization of random analytic functions in the mixed-norm space
${\mathcal F}(\infty , q, \alpha )$
, an endpoint version of Fock spaces, via entropy integrals; (b) a complete description of random lacunary elements in Fock spaces; and (c) a complete description of random multipliers between different Fock spaces.
Pelatihan Model Pengembangan Kurikulum 2013
Authors: Ahmad Ahmad , Ardian Edi , Muthalib A. , IP Edi Susrianto , Khairuddin Khairuddin 
Published: July 2022

The curriculum as several educational plans needs to be developed dynamically according to the needs and changes that occur in society with reference to the development of curriculum models. In line with this, among the many models of curriculum development, one that must be considered is choosing a curriculum development model. The selection of the development model is not based on the advantages and benefits and opportunities for optimal results, but also needs to be adapted to the education system and education processing system adopted and which educational concept model is used. serves as a means to facilitate a communication, or as a perspective guide for making decisions, or as a planning guide Therefore, the model can help us form the concept of the process by showing certain principles and procedures, as for the purpose of this mentoring is to provide insight to teachers in the development of the 2013 curriculum model. In addition, teachers who pursue escape are expected to improve their skills in carrying out learning activities. To achieve the expected goals of this training, lectures, demonstrations, exercises and assignments are used. The targets in this service are teachers SMA Tengku Sulung districts Sungai Batang. The methods used are in the form of seminars, demonstrations, and exercises or assignments.
The Foreground Approach to Motivating Students (FAMS): Unveiling a Remedial Module for Enhancing Listening and Speaking Skills among English as Second Language (ESL) Students
Authors: Shitu Fatima Muhammad 
Published: July 2022

Purpose: This paper is an overview of the listening and speaking skills module titled ‘’Foreground Approach to Motivating Students (FAMS)’’ developed by the writer. An action research, the FAMS module was developed in response to the urgent need to tackle issues relating to ineffective communication via the processes of listening and speaking among ESL students in the Department of English of the Federal College of Education Kano Nigeria. The purpose of designing the module is to provide students with useful and flexible resource materials that gives them the opportunity to continuously practice listening and speaking beyond the classroom.
Methodology: Designed on the framework of the ‘Think-Pair-Share' collaborative approach, the module operates in such a way that students can work or navigate through tasks independently at first and then work in pairs, in groups and or in whole class as well as share ideas and collaborate on tasks and projects.
Results: In this paper, the researcher unveils the different sections of the module. Each sections contain informative descriptions and explanations of the contents of each units. Additionally, suggestions for the implementation as well as the benefits of using the module especially by ESL students were provided.
Unique contribution to practice, theory, and strategy: Even though, the implementation of the module is still in progress, it envisaged that the outcome will yield positive results. The findings from its pilot testing will be used to improve the module. Finally, it is recommended that stakeholders in Higher Education, such as the government, the private and public sectors, should provide financial support to aid the publication, mass production and dissemination of the module throughout Colleges of Education in Nigeria and beyond.
UTILIZATION OF SOCIAL MEDIA AND ENTREPRENEUR KNOWLEDGE ON ENTREPRENEUR INTEREST STUDENT OF STIE PEMUDA SURABAYA
Authors: Anisa Nur Aini , Rachma Evi Aulia , Arifin Syamsul 
Published: July 2022

This study aims to analyze the influence of the use of social media and entrepreneurial knowledge on the entrepreneurial interest of STIE Pemuda students both partially and simultaneously. This research is a descriptive quantitative research. The sample used was 100 students who had taken entrepreneurship courses. The data analysis method uses multiple linear regression analysis techniques. The results showed that partially the use of social media and entrepreneurial knowledge had a positive and significant effect on the entrepreneurial interest of STIE Pemuda Surabaya students. Simultaneously that the use of social media and entrepreneurial knowledge has a positive and significant effect on the entrepreneurial interest of STIE Pemuda Surabaya students
The THE EFFECT OF MUDHARABAH FINANCING ON THE ROA (RETURN ON ASSET) IN SHARIA COMMERCIAL BANKS FOR THE PERIOD 2014-2019
Authors: Sholihah Imro’atus , Salwa Alivia Meisda , Rabbani Didin Burhanuddin 
Published: July 2022

The development of the sharia economy in Indonesia continues to experience rapid development, especially in the banking sector. Where the banking world is given a great opportunity by the government to carry out its business activities based on sharia principles. As a financial institution, Islamic banks must have differences with conventional banks, especially in terms of financing. Islamic banks are more focused on financing with the principle of profit sharing which is expected to be able to meet the criteria of liquidity, profitability, and solvency. To achieve high profitability, funds are required in appropriate financing. One of the ratios to measure the level of profitability is the Return On Asset (ROA) ratio. The purpose of this study is to determine whether there is an effect of Mudharabah financing on ROA generated by Islamic Commercial Banks for the 2014-2019 Period.
This research method is included in the type of quantitative research with an associative approach. Population is taken from the annual report of 14 Islamic Commercial Banks. The sampling technique used simple random sampling. The research sample was obtained in the form of the annual financial reports of 5 Islamic Commercial Banks for the period 2014-2019. Where the data collection uses secondary data obtained from the Banking Statistic Report published by the Financial Services Authority (OJK) and the annual Financial Report published by each Islamic Commercial Bank.
The results of testing the regression coefficients by coefficients obtained the sig value of mudharabah financing of 0.717 > 0.05. This means that the independent variable mudharabah has no significant effect on the dependent variable Return on Assets (ROA). So this shows that Ho is accepted and Ha is rejected, with the conclusion that partially mudharabah financing has no significant effect on the Return on Assets (ROA) of Islamic Commercial Banks for the 2014-2019 period.