bluuebunny/crossref_metadata_2025_split huggingface dataset:
Combination therapy for benign prostate hyperplasia-related urinary symptoms
Authors: Shkodkin S. V. , Pokrovskiy M. V. , Krasnyak S. S. , Polishchuk A. V. , Chirkov S. V. , Churikova O. V. , Kravtsova N. A. 
Published: April 2022

Introduction. Non-neurogenic lower urinary tract symptoms (LUTS) are a serious polyetiologic problem in the male population. The side effects of the medication agents used to treat LUTS significantly reduce treatment compliance. According to the literature data, the frequency of refusal for the proposed treatment during the year varies from 20 to 80%. Several studies have shown the benefits of herbal medicine for LUTS concerning the fewer side effects and increased adherence to treatment. However, to obtain a high-level recommendation base, clinical trials are required.Purpose of the study. To evaluate the effectiveness of Gardaprost® in LUTS combination therapy.Materials and methods. The study included 57 men aged 60 – 70 years with diagnosed medium- or large-volume benign prostatic hyperplasia (BPH) and moderate-to-severe LUTS according to I-PSS, morphologically excluded prostate cancer, without urinary infection signs. The patients were randomized into two follow-up groups. Tamsulosin 0.4 mg q.d. was prescribed to patients in the control group. Patients of the main group received Gardaprost® 0.4 mg q.d. in addition to Tamsulosin. The follow-up period in both groups was one-year. The statistical analysis includes data from 56 men. To evaluate therapy at the screening visit and on days 180 and 360, I-PSS, urination diary, IIEF-5, urinalysis, prostate-specific antigen, uroflowmetry, ultrasound were analyzed. Paired t-test and one-way ANOVA test were used to determine intergroup differences in normally distributed variables. For variables with a distribution other than normal, Friedman's two-way ANOVA for related samples was used. Events with a probability greater than 95% were considered statistically significant.Results. At the time of inclusion in the study, the groups were comparable concerning the control parameters. In the main group, there was a more pronounced positive dynamics in the I-PSS score, maximum urine flow rate, and post-void residual urine volume, which corresponded to 7.9 ± 2.1 points, 18.0 ± 7.3 ml/sec, 23.6 ± 13.6 ml vs 19.7 ± 7.2 points, 10 ± 3.5 ml/sec, 65.9 ± 33.2 ml in the main and control groups, respectively (p < 0.001). Additionally, in the main observation group, a decrease in prostate volume was recorded by 18.8% (p < 0.001) was recorded.Conclusion. We have obtained encouraging long-term results from the use of Gardaprost® in combination therapy of moderate-to-severe LUTS caused by medium- and large-volume BPH.
Digital Health Solutions and State of Interoperability: Landscape Analysis of Sierra Leone
Authors: Chukwu Emeka , Garg Lalit , Foday Edward , Konomanyi Abdul , Wright Royston , Smart Francis 
Published: April 2022

Background
The government and partners have invested heavily in the health information system (HIS) for service delivery, surveillance, reporting, and monitoring. Sierra Leone’s government launched its first digital health strategy in 2018. In 2019, a broader national innovation and digital strategy was launched. The health pillar direction will use big data and artificial intelligence (AI) to improve health care in general and maternal and child health in particular. Understanding the number, distribution, and interoperability of digital health solutions is crucial for successful implementation strategies.

Objective
This paper presents the state of digital health solutions in Sierra Leone and how these solutions currently interoperate. This study further presents opportunities for big data and AI applications.

Methods
All the district health management teams, all digital health implementing organizations, and a stratified sample of 72 (out of 1284) health facilities were purposefully selected from all health districts and surveyed.

Results
The National Health Management Information System’s (NHMIS’s) aggregate reporting solution populated by health facility forms HF1 to HF9 was, by far, the most used tool. A health facility–based weekly aggregate electronic integrated disease surveillance and response solution was also widely used. Half of the health facilities had more than 2 digital health solutions in use. The different digital health software solutions do not share data among one another, though aggregate reporting data were sent as necessary. None of the respondents use any of the health care registries for patient, provider, health facility, or terminology identification.

Conclusions
Many digital health solutions are currently used at health facilities in Sierra Leone. The government can leverage current investment in HIS from surveillance and reporting for using big data and AI for care. The vision of using big data for health care is achievable if stakeholders prioritize individualized and longitudinal patient data exchange using agreed use cases from national strategies. This study has shown evidence of distribution, types, and scale of digital health solutions in health facilities and opportunities for leveraging big data to fill critical gaps necessary to achieve the national digital health vision.
Exploring the Reasons for Low Cataract Surgery Uptake Among Patients Detected in a Community Outreach Program in Cameroon: Focused Ethnographic Mixed Methods Study
Authors: Mbwogge Mathew , Nkumbe Henry Ebong 
Published: April 2022

Background
Vision 2020: The Right to Sight, was one potential way to deal with the barriers surrounding cataract surgery and improve access to eye care. To this effect, the Magrabi International Council of Ophthalmology (ICO) Cameroon Eye Institute (MICEI) has performed more than 1000 sight-restoring cataract surgeries among patients referred from outreach camps. However, quite a good number of patients diagnosed with cataracts during community screening camps fail to present for surgery. This study sought to explore some of the challenges to accepting cataract surgery among community-diagnosed patients with cataract, patients operated for cataract, and community members.

Objective
The study objective was 5-fold: (1) to assess the level of awareness about cataract and available treatment, (2) to explore barriers to cataract surgery uptake, (3) to assess people’s perception about the outcome of cataract surgery, (4) to understand people’s perception about free cataract surgery, and (5) to explore reasons for outright refusal of cataract surgery.

Methods
This was a focused ethnographic study from December 2018 through February 2019 in 3 different communities of the Center Region of Cameroon, in which patients with cataract were diagnosed. The study sample was composed of patients operated for cataract, those diagnosed with cataract, key informants, and community members. Focus group discussions (FGDs), personalized in-depth interviews, and a short demographic questionnaire were used to collect data. Data were analyzed using a Microsoft Excel spreadsheet and Stata 14 (StataCorp). Data were presented using tabular and graphical methods.

Results
A total of 29 subjects (19 men) with a mean age of 54.5 (SD 14.5) years took part in the study. The most prominent barriers to cataract surgery were found to be cost (25/29, 86%) and fear of surgery (17/29, 59%). It was also noted by 41% (12/29) of subjects that those who do not take up cataract surgery turn to traditional medicine. Other barriers included the lack of awareness of available treatment (6/29, 21%), no perceived need (5/29, 17%), cultural beliefs and superstition (4/29, 14%), and negligence (4/29, 14%).

Conclusions
We found cost (25/29, 86%) and fear (17/29, 59%) to be the main barriers. Belief in traditional medicine and superstition were the main drivers of fear. The implementation of a tiered pricing system, counseling training for key informants, incentives for the referral of patients with cataract, mass media engagement, advocacy, training and active involvement of traditional doctors as key informants, acquisition of a 4×4 outreach van, and motorbikes for camp organizers were some of the recommendations based on our results.
Patient Activeness During Online Medical Consultation in China: Multilevel Analysis
Authors: Cao Bolin , Huang Wensen , Chao Naipeng , Yang Guang , Luo Ningzheng 
Published: April 2022

Background
Online medical consultation is an important complementary approach to offline health care services. It not only increases patients’ accessibility to medical care, but also encourages patients to actively participate in consultation, which can result in higher shared decision making, patient satisfaction, and treatment adherence.

Objective
This study aims to explore multilevel factors that influence patient activeness in online medical consultations.

Methods
A data set comprising 40,505 patients from 300 physicians in 10 specialties was included for multilevel analysis. Patient activeness score (PAS) was calculated based on the frequency and the proportion of patient discourses to the total frequency of doctor-patient interactions. Intraclass correlation coefficients were calculated to identify between-group variations, and the final multilevel regression model included patient- and physician-level factors.

Results
Patients were not equally active in online medical consultations, with PASs varying from 0 to 125.73. Patient characteristics, consultation behavioral attributes, and physician professional characteristics constitute 3 dimensions that are associated with patient activeness. Specifically, young and female patients participated more actively. Patients’ waiting times online (β=–.17; P<.001) for physician responses were negatively correlated with activeness, whereas patients’ initiation of conversation (β=.83; P<.001) and patient consultation cost (β=.52; P<.001) in online medical consultation were positively correlated. Physicians’ online consultation volumes (β=–.10; P=.01) were negatively associated with patient activeness, whereas physician online consultation fee (β=.03; P=.01) was positively associated. The interaction effects between patient- and physician-level factors were also identified.

Conclusions
Patient activeness in online medical consultation requires more scholarly attention. Patient activeness is likely to be enhanced by reducing patients’ waiting times and encouraging patients’ initiation of conversation in online medical consultation. The findings have practical implications for patient-centered care and the improvement of online medical consultation services.
que pode a pergunta-criança na formação de professoras/es? Algumas experimentações teórico-práticas
Authors: Dalmaso Alice Copetti , De Oliveira Marilda Oliveira , Rigue Fernanda Monteiro 
Published: April 2022

Este artigo aborda a problematização: O que podem as perguntas das crianças, tomadas como problemas de estudo e pesquisa, num espaço de formação de futuros/as pedagogos/as? Vinculado às experiências das pesquisadoras/docentes no processo de desenvolvimento de uma disciplina em um curso de Pedagogia, sob uma perspectiva filosófica da criança, o caminho metodológico se deu a partir do processo investigativo sobre as perguntas-crianças, acreditando que as mesmas não configuram unicamente uma estratégia para ensinar Ciências, mas, sobretudo de aprender, aprender a entrar em contato com aquilo que não é dado a priori, que ensejam novos modos de desejar-conhecer o mundo da criança, como percebem-relacionam com os acontecimentos científicos, como existem no e para o mundo. Experimenta-se um movimento que comece com povoar no mundo um devir-criança, uma pergunta-criança em nós.
Rejection of Funeral for Covid-19 Patients: Indonesian Legal Perspective
Authors: Wiryani Fifik , Sugiharto Setyo , Nasser M , Najih Mokhammad 
Published: April 2022

Purpose of the study:This study aims to solve the problem of citizens who refuse funerals/bodies of Covid-19 patients.Methodology The method used in this study is a normative juridical method using statutory, conceptual and case approaches.Results This study found that it is necessary to socialize, educate and communicate to the citizens that the Covid-19 bodies have gone through stages in accordance with medical protocol and WHO in the treatment/repatriation of bodies so that there should be no need for excessive fear while if residents refuse funerals Covid-19 patients' bodies there are sanctions including moral sanctions, fines and criminal confinement.Applications of this studyThis research can be used by academics and practitioners in health law, so that they can create an instrument to socialize the acceptance of Covid-19's bodies in the community.Novelty/ Originality of this study The bodies of Covid-19 patients have been carried out the repatriation (management) of the bodies in accordance with the standards of who's health protocol (World Health Organization), namely the bodies wrapped in three layers of shrouds and linen and two layers of body bags. then the body in Tayyamum using dust, the body and then placed into the coffin that was placed typical and has been sprayed disinfectant liquid, then the coffin closed tightly using silicone glue and then given nails on each side of the coffin.
Impact of Structured, Systematic and Massive Violations In the General Election
Authors: Mahyudin Mahyudin , Haryanto Edy , Marsinah Rahmah 
Published: April 2022

Authority in resolving disputes regarding the results of general elections is the authority of the constitutional court granted by the constitution. While the authority in resolving violations is structured, systematic and massive is the authority of the electoral supervisory body granted by law. In the dispute over the results of the general election, which was decided by the constitutional court, the constitutional court did not have the authority to test the petition filed on the basis of a structured, systematic and massive violation because the constitutional court only based on the dispute over the results as intended in its authority. The court verdict has been in accordance with the authority held according to the original instruction given by the constitution, which wants the implementation of elections that are sovereign and carried out on a direct, public, free, confidential, honest and fair basis.
<strong>The relationship of the formation of dental fear between mothers and their 7 to 9 year-old children</strong>
Authors: Cheema Jasmine Kaur , Gartika Meirina , Herdiyati Yetty 
Published: April 2022

Introduction: Dental fear is a common occurrence that responds to the stress induced by various dental procedures. Its intensity varies from nervousness and anxiety to dental phobia, and it is considered the main barrier to successful completion of treatment. This research aims to analyse the relationship of the formation of dental fear between mother and their 7 to 9-year-old children. Methods: The research design was analytical studies with a cross-sectional survey technique, with samples chosen by the simple random sampling method. Thirty-five mothers and children aged 7-9 years who attended Neglasari 2 and Neglasari 5 Public Elementary School, Sadang Serang, Bandung, were the respondents. This study used a questionnaire called the Dental Subscale of the Children's Fear Survey Schedule (CFSS-DS), tested and proven to be a reliable and valid psychometric instrument for dental fear evaluation in children in Bahasa Indonesia. This study was analysed using Spearman's rank correlation coefficient. Results: The mean score of the mothers was 24.314, and the mean score of the children was 23.571. The correlation value was 0.765. The figure scales in the 'strong' criteria. Conclusion: There is a strong relationship between the formation of dental fear in mothers and their 7-9 years-old children.
A Biomimetic Approach to Protective Glove Design: Inspirations from Nature and the Structural Limitations of Living Organisms
Authors: Irzmańska Emilia , Jastrzębska Aleksandra , Michalski Marek 
Published: April 2022

Abstract
Drawing inspiration from nature for the design of new technological solutions and smart materials constitutes an important development area for engineers and researchers in many disciplines. Biomimetic materials design brings numerous benefits, especially the possibility of implementing promising interdisciplinary projects based on effective existing solutions that have emerged in the course of natural evolution.
A major aspect of biomimetic materials design, especially relevant to protective gloves, is the identification of an optimum combination of the physicochemical properties and microstructural characteristics of a surface with a view to its potential applications. Properties such as wetting and adhesion can be adjusted by modifications of the surface morphology both on micro- and nanoscales. From the standpoint of the occupational safety performance of polymeric protective gloves, biomimetic materials should exhibit two crucial properties: reversible adhesion (via a large number of contact points) and hydrophobicity (water repellence).
This review analyzes the superhydrophobic and reversible adhesion patterns found in nature that can be used to improve the properties of polymeric protective gloves with major commercial implications.
Prevalence of left atrial septal pouch among patients with embolic stroke of undetermined source or stroke of known etiology: A retrospective study
Authors: Steyaert Hugo , Castro Rodriguez Jose , Gazagnes Marie-Dominique , Morissens Marielle 
Published: April 2022

Abstract

Background and objectives
Cryptogenic strokes can be defined by the criteria established for an embolic stroke of undetermined source (ESUS). Some embolic events might be caused by a left atrial septal pouch (LASP), due to the potential of thrombus formation. In this study we aimed to determine if LASP is a risk factor for ESUS when compared to a population of strokes of known origin, the LASP screening rate in our institution and if LASP dimensions influences the risk of ESUS.

Methods
We retrospectively analyzed transesophageal echocardiograms (TEEs) in a large cohort of patients that had experienced ischemic strokes. Two authors performed blinded, independent searches for LASPs by reviewing 1152 TEEs from patients that had experienced a stroke or transient ischemic attack. We excluded 26 TEEs, due to incorrect imaging. Next, we reviewed patient medical files.

Results
Among the 1126 included patients, 148 had an ESUS (ESUS+ group) and 978 had strokes of known origin (ESUS– group). A LASP was present in 176 patients, including 32 patients (21.6% of LASPs) in the ESUS+ group and 144 patients (14.7% of LASPs) in the ESUS– group. In multivariate analysis, LASP was independently associated with ESUS (P = 0,019). 61.9% of LASPs that we found were not mentioned in reports from the original TEE operators.

Conclusion
This study demonstrated that LASPs were more prevalent in patients with ESUS than in patients with strokes of known origin. Our results gave rise to the question of whether anticoagulation would be appropriate for some patients with ESUS. New large-scale, prospective studies should be conducted to address this issue. Additionally, considering the low rate of LASP descriptions, we concluded that the awareness of operators should be raised to improve their success in identifying LASPs.
АЛГОРИТМЫ ИНТЕРПРЕТАЦИИ ПОКАЗАТЕЛЕЙ КАЧЕСТВА ПОВЕРХНОСТНЫХ ВОД
Authors: Валиев Всеволод Сергеевич , Шамаев Денис Евгеньевич , Хасанов Рустам Равилевич , Иванов Дмитрий Владимирович , Шагидуллина Раиса Абдулловна , Шагидуллин Рифгат Роальдович 
Published: April 2022

Использование научной интерпретации для принятия управленческих решений является известной проблемой, трудно разрешимой в силу разных способов оценки информации, получаемой различными природоохранными ведомствами и научными организациями. В связи с этим актуальной задачей является создание специализированных программных комплексов, позволяющих использовать современные методы статистического анализа и системного моделирования для научных целей и при этом включающих алгоритмы интерпретации оценок состояния компонентов природной среды в виде простых формализованных показателей, а также наглядной их визуализации. В статье рассмотрен один из подходов к решению этой задачи, на основе которого реализован модульный программный комплекс расчета и интерпретации удельных комбинаторных индексов загрязненности воды и донных отложений.
Библиографические ссылки
1. Валиев В.С., Иванов Д.В., Шагидуллин Р.Р., Хасанов Р.Р., Шамаев Д.Е., Мустафина Л.К., Шурмина Н.В., Богданова О.А. Вероятностная оценка загрязнения поверхностных вод (на примере реки Казанка) // Вода: химия и экология. 2019. № 1‒2. С. 69‒76.2. Валиев В.С., Хасанов Р.Р., Шамаев Д.Е. Автоматизация обработки первичных данных мониторинга качества вод и донных отложений поверхностных водных объектов // Российский журнал прикладной экологии. 2021а. №3. С. 30‒35.doi: 10.24852/2411-7374.2021.3.30.353. Валиев В.С., Шамаев Д.Е., Иванов Д.В. Вероятностные подходы к оценке загрязненности поверхностных вод // Российский журнал прикладной экологии. 2021b. №3. С. 36‒42. doi: 10.24852/2411-7374.2021.3.36.424. РД 52.24.643‒2002. Метод комплексной оценки степени загрязненности поверхностных вод по гидрохимическим показателям.
PENGEMBANGAN E-MODUL DALAM LAYANAN BIMBINGAN KELOMPOK TEKNIK HOME ROOM TENTANG SELF EFFICACY PADA SISWA SMP MUHAMMADYAH 1 KALASAN
Authors: Adi prasetyo Dimas , Akhmad Fajar Prasetya  
Published: April 2022

Penelitian ini bertujuan untuk mengetahui kelayakan media penunjang layanan bimbingan kelompok berbasis elektronik berupa modul elektronik tentang self efficacy. Jenis penelitian ini R&D (Research and Development) dengan metode Brog and Gall. Model pengembangan ini hanya sampai tahap revisi produk saja. Studi pendahuluan dengan observasi dan wawancara, serta didukung oleh hasil pernyataan guru BK. Subjek penelitian siswa Smp Muhammadyah 2 kalasan tahun ajaran 2019/2020. Hasil penelitian pengembangan ini diukur berdasarkan penillaian dari uji ahli materi dan uji ahli media. Hasil penilaian uji ahli materi mendapatkan nilai sebesar 87,5 dengan kategori Sangat Baik. Sedangkan Uji Ahli Media mendapatkan nilai sebesar 81,25 dengan kategori Baik. Hasil penilaian secara keseluruhan dengan nilai rata-rata yang didapat sebesar 84,375 dengan kategori Sangat Baik. Berdasarkan hasil tersebut maka Pengembangan e-modul dalam layanan bimbingan kelompok teknik home room tentang self efficacy pada siswa SMP Muhammadyah 1 Kalasan Layak untuk digunakan.