bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE EFFECTS OF THYROID-STIMULATING HORMONE, FREE THYROXINE LEVELS, AND THYROID ANTIBODIES ON MEAN PLATELET VOLUME: ORIGINAL RESEARCH
Authors: ÖZTÜRK Mine , AKSOY Hilal 
Published: March 2022

Background: Coagulation abnormalities has been reported in patients with impaired metabolism of thyroid hormones. Platelets play an important role in coagulation and Mean Platelet Volume has been considered as an inflammatory biomarker in multiple diseases.
Objectives: The aim of this study was to investigate whether any relationship exists between the values of thyroid-stimulating hormone, free thyroxine, anti-thyroid peroxidase, anti-thyroglobulin and those of the MPV.
Methods: Patients who were admitted to the Endocrinology outpatient clinic between October 2013 and July 2019 with a pre-diagnosis of thyroid disease were included in the study. The data were analyzed with IBM SPSS V23. Compatibility with normal distribution was examined with the Shapiro Wilk test. The relation between the variables was evaluated with Spearman rank correlation.
Results: Records of 1098 patients were examined. There is a very weak positive relationship between TSH and MPV (r: 0,075), there is no significant relationship between ST4, Anti TPO, Anti TG and MPV.
Conclusion: Patients have high TSH values display a increased MPV should hence be acknowledged in risk prediction of thrombotic events.
Administering Geriatric Pneumonia Cases without Waiting for CRP Results, is It Practicable?
Authors: CİZMECİOGLU Ahmet , GÖKTEPE Mevlüt Hakan , AKAY ÇİZMECİOGLU Hilal , HATIR Ahmet Emre , BARDAKÇI Handan 
Published: March 2022

Background: C-reactive protein (CRP) is a notable marker of many diseases. Accordingly, in most cases, the clinical management of infectious diseases is revised based on CRP alterations. This study thus attempted to predict CRP alterations via immature granulocyte count (IGC) and nucleated red blood cell count (NRBC) in a geriatric population with pneumonia.
Methods: We carried out our study in the intensive care unit of a private hospital by retrospectively reviewing the laboratory findings of geriatric patients with pneumonia and an age-matched control group in the same ICU.
Results: In total, we reviewed 495 hospitalization days (the summed amount of days for all 43 patients) and 221 hospitalization days (the summed amount of days for all 20 controls) records. In the group comparisons, we found a statistical significance in the patient group for both IGC (p = 0.001) and NRBC (p = 0.002). Comparing IGC to CRP measures from the following day and the day after that, there was a statistical significance in IGC (p = 0.001) but not in NRBC (p = 0.156). Further, IGCs below 0.3 x 103 and above 0.5 x 103 were better able to predict CRP alterations.
Conclusion: In geriatric patients with pneumonia, IGC is more effective than NRBC in predicting CRP variations before their actual occurrence, with the mean estimation time at least 2 days prior.
Detection and endoscopic treatment of foreign bodies in the upper gastrointestinal system of the geriatric patients
Authors: COŞKUN Orhan , ÇAPRAZ Mustafa , KAYA Ahmet , ÇETİN Zeynep 
Published: March 2022

Abstract
Introduction: Ingestion of foreign bodies is a worldwide problem associated with severe morbidity and mortality. The incidence of foreign bodies ingestion increases in the elderly population due to impaired intraoral sensitivity and swallowing reflex, visual problems, tooth loss, and mental disorders.
Material and Method: All patients admitted with foreign body ingestion were retrospectively screened and patients over 65 years of age were included. All patients were managed by a flexible endoscope.
Results: 49 patients referred with the diagnosis of foreign body ingestion between January 2016 and May 2020 were retrospectively screened. Geriatric population consisted of 24 (49%) patients, mean age was 77.4±7.8 years and 15 (62.5%) were male.The most common symptom at admission was dysphagia in 41.7% of patients. The most common ingested foreign bodies are meat and food in 58.3% of the patients (p
Peran Komunitas Pecinta Sejarah (Kompas) dalam Mendukung Kegiatan Pembelajaran Sejarah
Authors: Puspadewi Erika , Winarti Murdiyah 
Published: March 2022

AbstractThe title of this research is “The Role of Historical Community (KOMPAS) in Supporting History Learning (a Descriptive Study of an Extracurricular KOMPAS at SMAN 22 Bandung.”The researcher’s background takes the theme of the research based on an interest in extracurricular activities in field of historical study at Senior High School. The choice of the Historical Community as the object of research is because this community the only extracullicullar based on historical learning that exist in Bandung and has not yet received attention among academics. The main problem in this research is “What is the role of the historical community (KOMPAS) in supporting students historical learning at school?” Based on these problems, the writer divides them into three problem formulations. How was the development of the Historical Community (KOMPAS) in 2015-2019? How has the Historical Community (KOMPAS) designed its programs to support history learning? What is the impact of the Historical Community (KOMPAS) on learning history in 2015-2019?.The method used in this research is descriptive study. The results of this study indicate that the background to the establishment of the Historical Community (KOMPAS) is the development of a history study group that is engaged in developing students' historical insight and skills. After the Historical Community (KOMPAS) was officially established as an extracurricular, this group attempted to create interactive history learning programs that support history learning. The impact of theHistorical Community at SMAN 22 Bandung is to provide a variety of learning resources in developing history learning materials.
Perkembangan Surat Kabar dalam Pusaran Politik: Kajian Surat Kabar Sinar Harapan 1961 – 1986
Authors: Sari Risca Wulan , Winarti Murdiyah , Darmawan Wawan 
Published: March 2022

Penelitian ini bertujuan untuk melakukan studi mendalam mengenai dinamika perkembangan surat kabar pada masa transisi pemerintahan soekano menuju soeharto yang mana dalam perjalannya sebagai sebuah surat kabar mendapati beberapa pengekangan hingga pencabutan surat izin penerbitan karena dianggap tidak selaras dengan tujuan pemeritah saat itu. Secara umum penelitian ini ingin menjawab pertanyaan mengenai “bagaimana dinamika perjalanan surat kabar dalam masa pemerintahan otoriter, khususnya surat kabar Sinar Harapan di Indonesia?”. Untuk menguji permasalahan, peneliti melakukan penelitian dengan menggunakan metode historis yang mencakup empat langkah penelitian. Langkah-langkah penelitian diantaranya yaitu pengumpulan sumber tertulis melalui studi literatur (heuristik), kritik sumber, interpretasi atau analisis sumber dan historiografi. Peneliti juga menggunakan konsep untuk menyederhanakan analisis, diantaranya konsep Surat Kabar, Otoriter, politik, pemerintah. Sebuah rasionalisasi untuk studi surat kabar ini, karena banyak perspektif tentang klaim yang dibuat oleh pemerintah atau surat kabar itu sendiri. Analisis teori otoriter muncul dalam bentuk pertanggungjawaban atas analisis surat kabar sebagai objek peluisan sejarah, disamping itu teori pers otoriter digunakan sebagai analisa pada dinamika perkembangan surat kabar di Indonesia.This research aims to conduct an in-depth study of the dynamics of newspaper development during the transition of Soekarno government to Suharto which on its way as a newspaper found some restraint until the revocation of the issuance license because it was considered not in line with the government's goals at that time. In general, this study wants to answer the question of "how is the dynamics of newspaper travel in the period of authoritarian rule, especially Sinar Harapan newspaper in Indonesia?". To test the problem, researchers conducted the study using historical methods that included four steps of research. Research steps include the collection of written sources through the study of literature (heuristics), criticism of sources, interpretation or analysis of sources and historiography. Researchers also use concepts to simplify analysis, including the concept of newspapers, authoritarians, politics, government. A rationalization for the study of this newspaper, due to the many perspectives on the claims made by the government or the newspaper itself. The analysis of authoritarian theory appears in the form of accountability for newspaper analysis as an object of historical immersion, in addition to the theory of the authoritarian press is used as an analysis on the dynamics of newspaper development in Indonesia.
Garda Perdamaian Dunia: Peranan Kontingen Garuda II Sebagai Pasukan Perdamaian di Republik Kongo (1960-1961)
Authors: Tanjung Wisnu Arsa 
Published: March 2022

ABSTRAKArtikel ini berjudul “Garda Perdamaian Dunia: Peranan Kontingen Garuda II Sebagai Pasukan Perdamaian di Republik Kongo (1960-1961)”. Permasalahan pokok yang dibahas dalam artikel ini adalah bagaimana usaha-usaha yang dilakukan oleh Kontingen Garuda II di Republik Kongo. Tujuan dari penelitian ini adalah untuk mengkaji lebih dalam terkait keterlibatan Kontingen Garuda II di Republik Kongo baik mengenai persiapan-persiapan untuk melaksanakan tugas di Republik Kongo dan kegiatan kegiatan yang dilakukan oleh Kontingen Garuda II selama di Republik Kongo pada tahun 1960 sampai 1961. Metode penelitian yang digunakan adalah metode historis yang meliputi beberapa langkah, yaitu heuristik (pengumpulan sumber) baik sumber lisan maupun tulisan, kritik sumber, interpretasi, dan historiografi. Untuk memperdalam analisis, penulis menggunakan pendekatan ilmu sosiologi, ilmu hubungan internasional. Teknik penelitian yang digunakan adalah studi literatur. Berdasarkan hasil penelitian, Pemerintah Indonesia ikut serta dalam mengirimkan pasukan perdamaian ke Republik Kongo dibawah naungan Perserikatan Bangsa-Bangsa pada tahun 1960 merupakan salah satu implementasi dari semangat politik anti kolonialisme dan imperialisme dengan menerapkan kebijakan politik luar negeri bebas aktif. Kegiatan-kegiatan yang dilakukan oleh Pasukan Kontingen Garuda II yakni mengatasi dan menengahi pemberontak-pemberontakan yang terjadi di Republik Kongo seperti mengatasi pertempuran pengiriman Kontingen Garuda II ke Kota Boende dan Coquihalville, pertempuran Kamina, peristiwa ledakan ranjau di Kamina serta mengatasi gerakan sparatisme di Provinsi Katanga. Selain itu, melakukan kegiatan patroli ke daerah Bikoro, Igende. Dari kegiatan tersebut Pasukan Kontingen Garuda II berhasil dalam melaksanakan tugas sehingga mendapatkan dampak yang sangat positif bagi pasuka. kontingen Indonesia sehingga pada tahun berikutnya Pemerintah Indonesia mengirimkan kembali Kontingen Garuda pada tahun 1962.
Report on the doctoral dispute at the Imperial Kazan University, December 14, 1908 on the defense of the dissertation of the doctor F. Ya. Kitaev
Authors: Zhilin Ivan N. 
Published: March 2022

On December 14, 1908, the doctor F. Ya. Kitaev, in the presence of the medical faculty, defended
dissertation for the degree of doctor of medicine, under the title:
"Obineration of swallowing movements". The work was carried out in the laboratory and under the supervision of Prof. N. A. Mislavsky.
The dissertator in his speech presented an outline of the history of the issue to which he devoted his work, and gave a concise review of the latter.
The first of the opponents to speak was Prof. Chuevsky, Having credited the author with the development of an interesting and complex issue, the opponent pointed out some external defects in the work.
P. L. Ladame. Tassel dorsalis caused by trauma. Le tabes trammathique, —Encephale. 1910, № 3
Authors: Likhnitsky Vitaly N. 
Published: March 2022

A 52-year-old man, shortly after a railway accident, during which he did not receive serious injuries, but got off with a fright, developed symptoms of traumatic neurasthenia, which did not disappear for several years; a few months after this collapse, signs of the incipient tabes dorsalis (tabes fruste) were ascertained; there is no definite indication of lues in the anamnesis.
Analyzing the case cited and comparing it with those previously published, Ladame comes to the conclusion that in the present case the development of tabes dorsalis accidentally coincided with the moments of the catastrophe; the existence of tabes dorsalis caused by trauma without previous infection with syphilis remains unproven by anyone, and the very possibility of such a development of the disease, on the basis of pathological and experimental data, must be considered unlikely.
N. R. Botvinlka, E. R. Hesse and E. A. Giese. On the issue of recognizing tumors of the cerebral appendage, - Russian Doctor, 1910, № 29
Authors: Baklushinsky Ivan D. 
Published: March 2022

Early recognition of this disease can serve as a sufficient guarantee of the success of its operative detection. Meanwhile, just as here there are no completely reliable signs indicating a tumor of the appendage, the most important sign is hemianopsia bitemporalis, loss of visual acuity, etc., but all these signs are inconsistent. Even more unstable are disorders from other cranial nerves and changes in the fundus. A very important recognition feature is the expansion of the Turkish saddle and the change in the shape of the parts of the base of the skull adjacent to it, which are established by x-rays.
The authors describe two cases of a tumor of the cerebral appendage, diagnosed by them mainly in this last way. Among other signs of this disease, they first noted the absence of reflexes from the Achilles tendons.
Chronicle and mixture. Volume XVII, № 4 (1910)
Authors: Baklushinsky Ivan D. 
Published: March 2022

The Ministry of Public Education submitted to the State Duma in the budgetary order a loan for the construction of a clinic for mental illness at the Imperial Kazan University.
According to the zemstvo doctor of the Slobodzeya section of the Tiraspol district, he had to observe in the village. Chobruchi is a curious psychic phenomenon. In this village, as early as the beginning of October, among the peasant Moldavian youth, men and women, mostly at the age of 15-18 years, a special psychosis appeared. The doctor was able to attend one of the meetings of these youth and witnessed the following phenomenon. Under the influence of some external stimulus, however slight, for example, tobacco smoking, one of those gathered suddenly has nervous attacks in the form of shaking his head and hands and shouting: devilish suggestion, damn smoke.
Chronicle of the Society of Neurologists and Psychiatrists at the Imperial Kazan University dated May 19, 1910
Authors: Osipov Victor P. , Voroshilov Vasily K. 
Published: March 2022

Presided over by prof. V. P. Osipov, with the secretary Dr. V. K. Voroshilov. Full members were present: prof. N. A. Mislavsky, Dr. V. P. Pervushin, I. A. Veselitsky, N. A. Donskov, M. A. Chalusov; guests of Dr. N. K. Goryaev, I. D. Baklushinsky, Belitsky and 3 senior medical students.
The visitor, Dr. I. D. Baklushinsky, made a report: "On the casuistry of the state of possession with the demonstration of the patient."
Prof. Mislavsky recalls a similar incident. Several times I have seen ordinary hypochondriacs who complained that a snake crawled into the mouth while sleeping with its mouth open in the hayfield. One of these cases is interesting in the sense of therapy: a very rich and hefty Kyrgyz came to my father with a request to cut his stomach. - "Why"? - "Firmly"! strikes at the same time on the stomach; I can't feel anything, I'm so tense. Nothing came out under chloroform. They tried to dissuade him, but it doesn't work, he insists on an operation. Tried induction current; the patient liked it very much; the next day is better; I left a week later relieved.
Effect of Supplementation with Dehydrated Cucumis melo and Copper on Reproductive Performance of Goats on Rangeland
Authors: Mendoza-Carreola J. , Calderón-Leyva G. , Veliz-Deras F.G. , Ángel-García O. , Arellano-Rodríguez F. , Contreras-Villarreal V. , Gaytán-Alemán L.R. 
Published: March 2022

Background: Microelements are essential for the reproduction of goats; short-term energy supplementation also improves the estrus and ovulatory response to estrus synchronization. The influence of supplementation of cantaloupe leftover and/or copper sulphate on the reproductive response of anovulatory adult goats on rangeland was evaluated. Methods: Sixty-seven mixed-breed adult goats were divided into four experimental groups: Control (C, n=16), without cantaloupe or Cu supplementation; Copper group (Cu, n=17), supplemented with 1 mL of copper sulphate at 2.5%; Cantaloupe group (Ca, n=17), supplemented with 200 g of Cucumis melo and Cu and cantaloupe group (Ca-Cu, n=17), supplemented with 1 mL of copper sulphate+200 g of Cucumis melo. Estrus of goats was synchronized and fixed-time artificial insemination (FTAI) was applied. Result: There was an increase in ovulation rate for the Ca-Cu goats when compared to C (1.93 vs 1.46, respectively). Also, embryo losses decreased for Ca-Cu goats compared to C, Cu and Ca (13 vs. 42.33%, p less than 0.05). It was concluded that the combined supplementation of cantaloupe leftovers and Cu could be an alternative to increase the ovulation rate and decrease embryo losses, a frequent reproductive problem in goats on rangeland.
Advanced Maternal Age as an Obstetric Risk Factor: Current Experience in a Hospital from Northwestern Spain
Authors: Peteiro-Mahia Laura , Blanco-López Susana , López-Castiñeira Noelia , Navas-Arrebola Rocío , Seoane-Pillado Teresa , Pertega-Díaz Sonia 
Published: March 2022

Introduction: Studies updating the evidence in advanced maternal age as an independent factor of obstetric risk are needed. The aim of this study was to determine the prevalence of ≥ 35-years-old pregnant women who give birth in a Spanish hospital in Northwestern Spain, and to describe the incidence of maternal and perinatal morbidity and mortality.Material and Methods: Retrospective follow-up observational study including women ≥ 20 years-old who gave birth over one year (n = 1378). Data were collected from medical records, including socio-demographic characteristics, comorbidities, gestational conditions, variables related with the delivery and perinatal outcomes. Multivariable logistic regression analysis was performed to determine the association of advanced maternal age with obstetric and perinatal outcomes.Results: Forty-two percent of pregnant women were ≥ 35 years old. In the multivariable analysis, advanced maternal age was associated with the likelihood of gestational diabetes (OR = 1.84; 95% CI = 1.10 - 3.07), hypothyroidism (OR = 2.11; 95% CI = 1.17 - 3.80), lower probability of an eutocic delivery (OR = 0.74; 95% CI = 0.56 - 0.98), and a hospital admission > four days (OR = 2.91; 95% CI = 1.95 - 4.35). An association with the rate of C-sections was not found (OR = 1.24; 95% CI = 0.89 - 1.72).Conclusion: A high prevalence of pregnant women of advanced maternal age was confirmed. There was a higher rate of comorbidities and longer hospital admissions in older women but not a higher rate of higher C-sections and other complications.
Establishment of a risk model by integrating hypoxia genes in predicting prognosis of esophageal squamous cell carcinoma
Authors: Xiao Wanyi , Tang Peng , Sui Zhilin , Wu Xianxian , Han Youming , Gong Lei , Yu Zhentao , Zhang Hongdian 
Published: March 2022

Abstract
Esophageal squamous cell carcinoma (ESCC) has a dismal prognosis and hypoxia plays a key role in metastasis and proliferation of ESCC. Thus, we aimed to develop a hypoxia-based gene signature to assist in the diagnosis and prognosis. We performed consensus clustering analysis based on differentially expressed hypoxia related genes (HRGs) acquired from the GSE53625 dataset and The Cancer Genome Atlas (TCGA), and used weighted gene co-expression network analysis to filter out candidate modules which were then intersected with differentially expressed genes from clustered subgroups to obtain HRGs. The HRGs were used for stepAIC algorithm to construct risk score models and validated in TCGA database. Independent prognostic factors after univariate and multivariate COX analyses were used to construct the prognostic nomogram. Immunohistochemical were used to detect protein expression levels of relevant genes. And the relationship between risk scores and tumor microenvironment was explored. A hypoxia risk model containing 6 genes (PNPLA1, CARD18, IL-18, SLC37A2, ADAMTS18 and FAM83C) was constructed by screening key HRGs. Poorer prognosis in the high-risk group than in the low-risk group. And Cox regression analysis showed that risk score was independent prognostic factors. Nomogram based on risk scores could well predict 1-, 3-, and 5-year survival. P53, Wnt, and hypoxia signaling pathways may be some regulatory mechanisms of hypoxia associated with tumor microenvironment. In addition, we confirmed the high expression of BGN and low expression of IL-18 in ESCC tissues. Our study determined the prognostic value of a 6-hypoxia gene signature and a prognostic model, providing potential prognostic predictors and therapeutic targets for ESCC.
Responses and adjustments of the coastal systems of Dominica (Lesser Antilles) when faced with an extreme event: Hurricane Maria (September 2017)
Authors: Battut Samuel , Rey Tony , Cécé Raphaël , Bernard Didier , Krien Yann 
Published: March 2022

Abstract
Dominica was hit hard by Hurricane Maria, a Category 5 storm when it passed over the island on September 18, 2017. This study aims to characterise the dynamics associated with this extreme event and their consequences in the medium term on the morphology and the coastal structures of this caribbean island nation. Based on a multi-site approach (9 sites), this study uses varied data (satellite and aerial images, databases, reports, numerical modelling) and the validation thereof via qualitative observations and topo-morphological surveys carried out in the field 18 months after the hurricane. The high-resolution modelling of the hydrometeorological conditions during the hurricane, the monitoring of the changes in the shoreline, and the field observations brought to light the prevalence of fluvio-sedimentary hazards (torrential flooding, ground movements) over marine hazards (marine flooding, storm swell) in the modification of the coastal landscapes. Phenomena of massive sediment discharge caused considerable damage to the buildings located in low-lying areas and flood plains and to road infrastructure, which hindered access to certain sectors of the island in the post-storm phase for a significant period of time. The more-limited damage of marine origin was exacerbated by the artificialisation of the coast and the establishment of a permanent shoreline. We demonstrate that the impact model for Hurricane Maria for the coastal areas of Dominica is the result of a combination of natural factors with a particular exposure and vulnerability of coastal populations and structures to hydrometeorological risks.