bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kierkegaard’s Strong Anti-Rationalism: Offense as a Propaedeutic to Faith
Authors: Kemp Ryan , Della Torre Frank 
Published: July 2022

Abstract
In a now classic paper, Karen Carr argues that Kierkegaard is a religious “anti-rationalist”: He holds that reason and religious truth exist in necessary tension with one another. Carr maintains that this antagonism is not a matter of the logical incoherence of Christianity, but rather the fact that genuine submission to Christ precludes approaching him through demonstration. In this essay, we argue that while Kierkegaard is in fact an anti-rationalist, the literature has failed to appreciate the full strength of his position. It is not just that reason and obedience are in tension; rather, Kierkegaard holds the stronger view that reason is actively offended by Christianity’s primary claims. Not only is reason incapable of generating any positive evidence for the truth of Christianity, more radically, it provides evidence against it. In order to make this case, we offer a close reading of Practice in Christianity, developing a typology of Kierkegaard’s account of Christ’s “offense.” Finally, having motivated Kierkegaard’s strong anti-rationalism, we consider why, on his account, anyone would want to be a Christian.
Kierkegaard and Religionswissenschaft: A Source- and Reception-Historical Survey (Part 1)
Authors: Ziolkowski Eric 
Published: July 2022

Abstract
The subject of this two-part article (the second part will be published in KSYB 2023) is the bearing of Søren Kierkegaard’s writings, and of their reception, upon the development of Religionswissenschaft or the comparative study of religion. This first part opens by taking account of Kierkegaard’s own awareness of, and relationship to, “non-Christian” religions (Judaism, Islam, Hinduism, Buddhism, religions of China, etc.), including his late reading of Schopenhauer; then considers Kierkegaard in juxtaposition with his contemporary F. Max Müller, the Sanskritist and foundational pioneer of comparative religion, and the two men’s contrasting relations to F.W.J. Schelling; and finally examines the interest taken in Kierkegaard by William James, Max Weber, and Gerardus van der Leeuw as early twentieth-century contributors through three different disciplines to the study of comparative religion.
Heiberg’s Article on History and Kierkegaard’s Critique
Authors: Stewart Jon 
Published: July 2022

Abstract
This article provides an introduction to Johan Ludvig Heiberg’s “On the Principle of the Beginning of History” from 1843. The Danish poet, playwright and critic attended Hegel’s lectures in Berlin in 1824 and returned to Copenhagen a convinced Hegelian. He spent the next two decades pursuing a campaign to spread the word about Hegel’s philosophy in the Kingdom of Denmark. His little-known article on history draws substantially on Hegel’s Lectures on the Philosophy of History, which had been published by Heiberg’s acquaintance Eduard Gans in 1837 as a part of the complete works edition of Hegel’s writings. Kierkegaard makes Heiberg’s article the object of criticism in The Concept of Anxiety and a draft of Prefaces. In the former he claims that Heiberg’s occupation with the beginning of world history trivializes the issue of sin. In the latter he charges Heiberg with plagiarism. The present article introduces Heiberg’s article and gives an account of Kierkegaard’s criticism.
Activity patterns and burrowing ecology of the giant pouched rat (Cricetomys emini) in Tshuapa Province, D. R. Congo
Authors: Kalemba Lem’s N. , Morgan Clint N. , Nakazawa Yoshinori J. , Mauldin Matthew R. , Malekani Jean M. , Doty Jeffrey B. 
Published: July 2022

Abstract
Rodents of the genus Cricetomys have been reported to be nocturnal with a bimodal activity pattern and to frequently change burrows. However, no studies to date have examined these ecological aspects with the use of radio-telemetry. Five C. emini were captured and radio-collared to study their activity patterns and burrowing ecology from 9 March to 15 April 2016. Nocturnal activity ranged between the hours of 18:00 and 05:00 with a probable reduction of activities between 20:00–23:00 and around 04:00 with diurnal activity between 06:00 and 17:00 h with a reduction of activity between 11:00 and 14:00. While the present study does confirm nocturnal activity and a bimodal pattern, this study also suggests greater diurnal activity as compared to previous studies. Additionally, data presented here also suggest that C. emini may not change burrows as frequently as previously reported.
LINC00665/miRNAs axis-mediated collagen type XI alpha 1 correlates with immune infiltration and malignant phenotypes in lung adenocarcinoma
Authors: Zhu Jun , Weng Yuan , Wang Fudong , Zhao Jun 
Published: July 2022

Abstract
Collagen type XI alpha 1 (COL11A1) as an oncogene has been reported in several malignant tumors. Herein, we aimed to explore the function of COL11A1 and its upstream regulators in lung adenocarcinoma (LUAD). COL11A1 expression prognostic significance, gene ontology, Kyoto Encyclopedia of Genes and Genomes, and immune infiltration were explored in LUAD. In vitro experimental measurements were implemented to validate the function of COL11A1 and LINC00665 in LUAD cells. Our study demonstrated that LINC00665-2 and COL11A1 were significantly upregulated in LUAD tissues compared with nontumor tissues. COL11A1 was positively correlated with multiple immune cell enrichment, suggesting that COL11A1 may be a prospective therapeutic target to enhance the efficacy of immunotherapy in LUAD. A regulatory mechanism LINC00665-2/microRNAs (miRNAs)/COL11A1 axis was identified to facilitate the tumorigenesis of LUAD. si-LINC00665 transfection induced the inhibition of growth and migration, and apoptosis was reversed by the overexpression of COL11A1 in LUAD cells. In conclusion, LINC00665 as a competing endogenous RNA sponging multiple miRNAs to modulate COL11A1 expression in LUAD, suggesting that LINC00665/miRNAs/COL11A1 axis may contribute to the pathogenesis of LUAD.
Effect of femoral head necrosis cystic area on femoral head collapse and stress distribution in femoral head: A clinical and finite element study
Authors: Zhang Zhaoming , Lin Tianye , Zhong Yuan , Song Wenting , Yang Peng , Wang Ding , Yang Fan , Zhang Qingwen , Wei Qiushi , He Wei 
Published: July 2022

Abstract
The purpose of this study was to investigate the effect of cystic areas of osteonecrosis of the femoral head (ONFH) on stress distribution and disease progression in the femoral head. A total of 85 patients (106 hips) diagnosed with Association Research Circulation Osseous stage II non-traumatic and non-surgical treatment were retrospectively analyzed. The presence of cystic areas and diameter of cystic areas were compared between the two groups. In addition, five spherical cystic areas of different diameters were constructed and the maximum stress was observed. There was a difference between the two groups in whether cystic areas appeared in the femoral head, with 49.1% in the collapse group showing cystic areas, which was significantly higher than that in the non-collapse group (18.4%) (P < 0.05). In addition, the diameter of the cystic areas was significantly larger in the collapsed group than in the non-collapsed group (P < 0.05). The maximum and mean von Mises stress value around the necrotic area and around the cystic area of the femoral head increased with the increase of the cystic diameter. Stress concentration areas can be generated around the cystic areas. The presence and increased diameter of the cystic areas accelerates the collapse of the ONFH femoral head.
All Designators are Rigid
Authors: Noonan Harold 
Published: July 2022

Abstract
In Naming and Necessity Kripke introduces the concept of a rigid designator and argues that proper names are rigid designators. He argues that in this way they are different from typical definite descriptions (though he allows that some definite descriptions, e.g., ‘the actual winner of the lottery’, ‘the square of 3’, are rigid designators). His opponents have either argued that names can be regarded as abbreviations of rigid descriptions (e.g., ‘actualized’ ones) or have tried to deny that names are rigid designators. I shall argue that no unambiguous descriptions are non-rigid. All unambiguous descriptions are rigid. The appearance of non-rigidity in descriptions is simply an illusion, a manifestation of ambiguity. I shall then go on to show that an explanation of the difficulty which has been found in extending the rigid/non-rigid distinction from singular terms to predicates follows.
Broadband plasmonic half-subtractor and digital demultiplexer in pure parallel connections
Authors: Wu Pei-Yuan , Chang Yun-Chorng , Huang Chen-Bin 
Published: July 2022

Abstract
Nanophotonic arithmetic circuits requiring cascaded Boolean operations are difficult to implement due to loss and footprint issues. In this work, we experimentally demonstrate plasmonic half-subtractor and demultiplexer circuits based on transmission-lines. Empowered by the unique polarization selectivity in the surface plasmon modal behaviors, both circuits are realized without cascading. The operations of the half-subtractor and demultiplexer can be performed using a single laser beam with three predefined linear polarizations. All of our experiments are performed using a 56 fs laser providing greater than 12.5 THz optical bandwidth. The experimental results are found in excellent quantitative accordance with numerical calculations. The photonic integrated circuit framework proposed in this work could pave the future avenue towards the realization of highly compact, multi-functional, on-chip integrated photonic processors.
Die aktuelle Lage der Kreuzfahrtindustrie: Besondere Herausforderungen für Finanzmanagement, Strategie und Marketing
Authors: Schabbing Bernd 
Published: July 2022

Zusammenfassung
Die internationale Kreuzfahrt wurde durch COVID 19 noch stärker als der Tourismus allgemein getroffen. Die unklare und auch wechselhafte Lage und Entwicklung von COVID 19 und der entsprechenden staatlichen Reaktionen erzwang 2020 und 2021 starke und kurzfristige Anpassungen der Kreuzfahrtreedereien bei der Durchführung von Kreuzfahrten. Dies führte 2020 und 2021 zu starken Rückgängen und Änderungen und so u.a. zu einem stark wachsenden Finanzierungsbedarf, womit sich insgesamt verschiedene ernste Herausforderungen für die Kreuzfahrtindustrie ergaben. Dies und die Charakteristik eines stark wettbewerbsorientierten Wachstumsmarktes veränderte die Lage und den Markt der Kreuzfahrtindustrie weltweit stark und wird auch über die Corona Zeit hinausreichen. Der vorliegende Artikel befasst sich mit den Veränderungen der Rahmenbedingungen sowie den wesentlichen Folgen und Herausforderungen für die Kreuzfahrtindustrie, die aus diesen Veränderungen folgten. Kernthemen sind die Finanzen, das Marketing sowie die Nachhaltigkeit, wobei ein Schwerpunkt auf den deutschen Kreuzfahrtmarkt gelegt wird.
Order-disorder (OD) structures of Rb2Zn(TeO3)(CO3)·H2O and Na2Zn2Te4O11
Authors: Eder Felix , Stöger Berthold , Weil Matthias 
Published: July 2022

Abstract
Single crystals of the two alkali metal zinc oxidotellurates(IV), Rb2Zn(TeO3)(CO3)·H2O and Na2Zn2Te4O11, were obtained by reactions of mixtures of ZnO, TeO2, Rb2CO3 (molar ratios 2:3:6) and ZnO, TeO2, Na2CO3 (molar ratios 2:3:10), respectively, with small amounts of water as a mineralizer. Both compounds crystallize as order-disorder (OD) structures of layers and feature a high stacking fault probability. The crystal structure of Rb2Zn(TeO3)(CO3)·H2O is composed of layers extending parallel to (100). The structure is composed of two kinds of non-polar OD layers consisting of trigonal-pyramidal [TeO3]2−, tetrahedral [ZnO4]6−, Rb1+, and CO3
2−, H2O, Rb2+, respectively. Different centrings of the layer groups lead to an ambiguity in the stacking arrangement. The crystal structure of Na2Zn2Te4O11 is built from layers extending parallel to (001). Trigonal-pyramidal [TeO3]2− and bisphenoidal [TeO4]4− polyhedra form [Te4O11]6− groups, which are connected by longer Te–O-contacts to form 1
∞[Te8O22]12− double chains oriented along either [100] or [010]. These chains form non-polar layers, which appear alternatingly in two orientations related by a fourfold rotoinversion. The Zn2+ and Na+ cations are located at the layer interface. The stacking ambiguity is due to different lattices of adjacent layers.
COMPARAÇÃO ENTRE O MÉTODO DA LARGURA EFETIVA E O MÉTODO DA RESISTÊNCIA DIRETA NO DIMENSIONAMENTO DE PERFIS CARTOLA FORMADOS A FRIO SUBMETIDOS À COMPRESSÃO
Authors: Filho Daniel Carlos Santos , Araujo Ricardo Rodrigues de 
Published: July 2022

Este trabalho trata do dimensionamento de perfis de seção cartola através do Método da Largura Efetiva e do Método da Resistência Direta, ambos presentes na Norma Brasileira ABNT NBR 14762:2010, visando comparar os valores encontrados. O programa GBTUL, baseado na Teoria Generalizada de Vigas (GBT), foi utilizado para determinar as cargas críticas de flambagem elástica. Observou-se a equiparação entre os valores determinados pelos dois métodos quando a carga axial de flambagem global elástica utilizada no MRD era determinada pelas prescrições da ABNT NBR 14762:2010. Nos casos em que os valores da carga global foram extraídos do GBTUL, os resultados se mostraram muito irregulares comparados com os do MLE. Constatou-se também que as propriedades geométricas calculadas pelo GBTUL para os perfis estudados apresentaram discrepâncias significativas em relação às apresentadas na ABNT NBR 6355:2012, podendo este ser o motivo da incoerência das cargas de flambagem global elástica fornecidas pelo GBTUL.
Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES
Authors: Brown Zuben P , Abaeva Irina S , De Swastik , Hellen Christopher U T , Pestova Tatyana V , Frank Joachim 
Published: July 2022

AbstractHepatitis C virus mRNA contains an internal ribosome entry site (IRES) that mediates end‐independent translation initiation, requiring a subset of eukaryotic initiation factors (eIFs). Biochemical studies revealed that direct binding of the IRES to the 40S ribosomal subunit places the initiation codon into the P site, where it base pairs with eIF2‐bound Met‐tRNAiMet forming a 48S initiation complex. Subsequently, eIF5 and eIF5B mediate subunit joining, yielding an elongation‐competent 80S ribosome. Initiation can also proceed without eIF2, in which case Met‐tRNAiMet is recruited directly by eIF5B. However, the structures of initiation complexes assembled on the HCV IRES, the transitions between different states, and the accompanying conformational changes have remained unknown. To fill these gaps, we now obtained cryo‐EM structures of IRES initiation complexes, at resolutions up to 3.5 Å, that cover all major stages from the initial ribosomal association, through eIF2‐containing 48S initiation complexes, to eIF5B‐containing complexes immediately prior to subunit joining. These structures provide insights into the dynamic network of 40S/IRES contacts, highlight the role of IRES domain II, and reveal conformational changes that occur during the transition from eIF2‐ to eIF5B‐containing 48S complexes and prepare them for subunit joining.
Pensar la historia desde la didáctica
Authors: Ramírez Achoy Jéssica 
Published: July 2022

El sentido público de la historia llega hasta el aula y, con este, las formas discursivas y conceptuales de la disciplina histórica adquieren otras lógicas en la escuela (Plá, 2021). Por esta razón, para el profesorado de primaria y secundaria, el conocimiento histórico alcanza nuevas finalidades, las cuales cambian tanto los objetos de la investigación que producen como las formas de interpretar la teoría social y la metodología. Esta reivindicación de una historia no disciplinar en las escuelas y colegios se fundamenta en el debate del para qué de la enseñanza, específicamente, de los estudios sociales. Lo anterior, tiene dos ideas iniciales que nos interesa comentar en este editorial y del debate de la Revista Perspectivas: a) las y los docentes requieren del conocimiento histórico como una base fundamental en su formación y ejercicio docente y b) ese conocimiento por sí mismo es insuficiente para saber enseñarlo, pues se necesita la didáctica para pensar la historia en el contexto escolar.
Accesibilidad en dos formas urbanas de la periferia interior. Análisis configuracional y de visibilidad
Authors: Ezquerra Isabel , Campos-Sánchez Francisco Sergio 
Published: July 2022

La construcción de las primeras periferias de muchas ciudades europeas entre los años cincuenta y setenta del pasado siglo se caracterizó por la profusión de actuaciones unitarias basadas en los principios del urbanismo funcionalista –polígonos de vivienda masiva– y otras formas que se produjeron en paralelo a estos como resultado de un crecimiento gradual, más o menos planificado, y más próximo al sistema tradicional basado en calles y manzanas – “periferias ordinarias”–. Frente a aproximaciones más específicas que ahondan en el carácter original de enclaves de los polígonos de vivienda, sin considerar su actual contexto urbano, esta investigación tiene por objetivo evidenciar y comparar morfológicamente las condiciones de accesibilidad que presentan ambos tipos de crecimiento urbano. El estudio se basa en una adecuación del modelo “Valor de Nodo y Lugar”, desarrollando el análisis configuracional multiescalar y de visibilidad en dos polígonos de la ciudad de Zaragoza y sus correspondientes “periferias ordinarias”. Los resultados evidencian que la situación relativa de los polígonos de vivienda en la ciudad ha cambiado con el tiempo, pasando en muchos casos de una posición de aislamiento en la periferia a una “posición pericentral”. Ambas formas se encuentran bien integradas en la red urbana a nivel global. Sin embargo, a escala intermedia los polígonos muestran una peor accesibilidad que los fragmentos de “periferia ordinaria”. A escala de actuación, también estos últimos se muestran más seguros visualmente y con mayor accesibilidad. Estos análisis pueden ser útiles a la planificación para mejorar la accesibilidad y dinamizar estas formas urbanas.
Outcomes of sepsis: a new look at old problems
Authors: Savochkina A. Yu. , Pykhova L. R. , Abramovskikh O. S. , Chetvernina E. A. , Poltorak A. E. 
Published: July 2022

Infections represent a common health problem in people at any age. Usually, a local reaction develops in response to the infection, and intensive treatment is not required. However, sometimes the response to infection is inadequate and may lead to organ dysfunction; such condition is defined as septic state. The pathophysiology of sepsis is multifactorial, and the immune system is directly involved in development of pathological processes accompanying septic conditions. Dysregulatory disorders in sepsis may be observed, in particular, those affecting immune system and, immediately, innate immunity, which presents the first line of immune defense. Currently, neutrophilic granulocytes are considered important players in development and maintenance of inflammatory processes, which is due to their ability to produce various inflammatory mediators. At the same time, at different stages of pathogenesis, immune factors and mechanisms act both as a generating factors and effectors of damage reactions, as well as the main components of the defense responses. Uncontrolled release of endogenous inflammatory mediators induced by microorganisms, and lack of damagelimiting mechanisms mutually synergize when promoting the organ dysfunction. Hence, dysfunction of the immune system may develop and deepen upon any inappropriate strategy of response to distinct infectious pathogen. The aim of our study was to assess the spectrum of microorganisms, levels of neutrophilic extracellular traps (NVL), PAD4, IL-6, IL-8 and their correlations in the patients with sepsis and septic shock, depending on the outcome of the disease. The study included 44 patients with sepsis and septic shock, and 20 apparently healthy donors. Peripheral blood samples were taken from the ulnar vein serially in dynamics, from the moment of diagnosis to clinical outcome. Microbiological and immunological studies have been carried out. The obtained data were processed with “SPSS Statistic 23.0” software. Development of septic conditions was found to be accompanied by a significant changes in the levels of studied immunological parameters (NLV, IL-6, IL-8 and PAD4). Toxicity of lysosomal enzymes and oxygen metabolites present in neutrophilic extracellular traps leads to endothelial damage, appearance of focal intravascular inflammation, which, along with damaging effects of microorganisms and their toxins, leads to development of organ failure and onset. High burden of these factors is most likely to cause lethal outcomes.
campo profesional de las/os Técnicas/os en Economía Social y Solidaria. Universidad Nacional de Quilmes, Argentina.
Authors: Zeballos Tania Ludmila , Mendy Guillermina , Altschuler Bárbara 
Published: July 2022

Este trabajo plantea un acercamiento a la caracterización del campo profesional de las/os Técnicas/os Universitarias/os en Economía Social y Solidaria de la Universidad Nacional de Quilmes (UNQ), Buenos Aires, Argentina, por medio del relevamiento de sus prácticas y actividades socio-laborales.
La Tecnicatura Universitaria en Economía Social y Solidaria (TUESS) es un trayecto educativo innovador y un espacio fundante en institucionalizar procesos de formación en Economía Social y Solidaria (ESS) en nuestro país, donde conviven múltiples dispositivos pedagógicos facilitadores de procesos de enseñanza y aprendizaje colectivos e inclusivos. La TUESS inicia en 2012 y se enmarca en el Observatorio del Sur de la Economía Social y Solidaria, CREES, Unidad Académica del Departamento de Economía y Administración de la UNQ.
Sobre un universo de 261 egresadas/os a la fecha, por medio de una triangulación metodológica realizamos relevamientos (encuestas y entrevistas), sistematizaciones y análisis de algunas variables sobre las/os egresadas/os del período 2014-2019, identificando sus prácticas profesionales desde las características que este trayecto ofrece y reconociendo prácticas que re significan y re-construyen subjetividades, valores y saberes.
Este trabajo se enmarca en la línea de investigación sobre Educación y Economía Social y Solidaria que venimos desarrollando desde 2012 en la UNQ, desarrollada en la actualidad desde el proyecto “Universidad, mercados y políticas públicas en Economía Social y Solidaria” (del Programa “Alcances y Desafíos del Desarrollo Territorial”), así como desde una Beca de Iniciación a la Investigación de la Secretaría de Investigación de la UNQ.
En este marco, la ponencia da cuenta de las características innovadoras de este trayecto formativo en ESS, su propuesta pedagógica y didáctica, aportando un análisis inicial sobre este campo profesional emergente y en configuración en nuestro país.