bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Transformational Leadership on the Effectiveness of Administrative Decisions: A Field Study at Pharmaceutical Manufacturers in Yemen
Authors: Ayedh Prof. Dr. Abdullatif Musleh Mohammed , Al-Qohfa Dr. Abdulkarem Saleh Hussein 
Published: July 2022

This study aimed to assess the effect of transformational leadership on the effectiveness of administrative decisions and to identify the level of practicing it in pharmaceutical companies in Yemen. It also aimed to identify any statistically significant differences among the participants› responses regarding the effectiveness of administrative decisions attributed to organizational variables, including company age, size and ownership. To achieve the study objectives, the descriptive analytical method was used and a questionnaire was administered to a sample of 330 participants selected by the complete census sampling method from nine pharmaceutical companies in Yemen. Only 273 questionnaires were valid for statistical analysis. Major findings revealed that the companies under study have shown paramount interest in the effectiveness of administrative decisions, including all dimensions, where the mean of the level of performance was high. However, the level of practicing transformational leadership did not reach the level of decision effectiveness, where the practice level was medium. Furthermore, there were differences at the level of the impact of the dimensions of transformational leadership on the effectiveness of administrative decisions; the highest effective difference was the individualized consideration, and the least one was the inspiration motivation. The study stressed the need to promote the practice of transformational leadership in companies so as to achieve effective administrative decisions.
Keywords: pharmaceutical manufacturers, effectiveness of administrative decisions, transformational leadership.
Impact of Employees’ Performance on Achieving Competitive Advantage: A Field Study in the Mobile Phone-Run Companies in Sana'a
Authors: Al-Nashmi Assoc. Prof. Dr. Murad Mohammed , Al-Ghashmi Dr. Muna Saleh Saleh 
Published: July 2022

This study aimed to identify the impact of the employees’ performance on the competitive advantage in the mobile phone-run companies in Sana’a. The population of this study was (1648) employees (male and female) from different administrative levels. The required sample for the study, according to Krejcie and Morgan, is (313) employees and the actual sample of the present study was (302) employees with a rate of (96.5%) of the required sample. The descriptive analytical approach was adopted and a questionnaire was used to collect the data. The findings revealed that the employees’ performance has an effect on achieving the competitive advantage, but it still does not meet the aspirations of the companies under consideration. Furthermore, the study found out that there are statistically significant differences in the average answers of the sample on achieving competitive advantage due to organizational variables represented in the number of employees and the name of company while these companies have not achieved differences in achieving the competitive advantage in terms of excellence, flexibility, innovation and responsiveness, according to the age variable. The study recommended that more attention should be paid to the reinforcement of the employees’ performance which can lead to the achievement of the competitive advantage in the companies instead of seeking external resources that are difficult to keep pace with.
Keywords: employees’ performance, mobile run companies, competitive advantage.
The Impact of Administrative Empowerment on the Employees' Creativity: A Case Study of Kamaran Factory in Hodeidah City
Authors: Amr Tariq Ali Abdullah , Zomailan Mohammed Abdurasheed Ali 
Published: July 2022

The study aimed to identify the impact level of administrative empowerment on employees' creativity at Kamaran Factory. The analytical descriptive method was used and the study population consisted of all the employees (400) who work in the factory. 133 employees were selected for the study using the random stratified method. The questionnaire was used to collect data from the study sample and the SPSS V20 package was used for the statistical analysis. Major study findings revealed that there were varying degrees of the level of practicing administrative empowerment and the employees' creativity in favor of the dependent variable (employees' creativity). There was also a statistically direct effect of the independent variable (administrative empowerment) on the employees' creativity at Kamaran factory. Further, (44%) of the variables that occur in the employees' creativity were attributed to the variables which occur in the administrative empowerment, and the remaining (56%) were attributed to other factors which are beyond the scope of this study.
Keywords: administrative creativity, training, entrusting of powers, administrative empowerment.
Teacher's Role in Developing Values of Civilization among High School Students in Buraydah City in Saudi Arabia
Authors: Fatima Jaber Al-Shahri  
Published: July 2022

This study aimed to identify the extent to which teachers practice their role in developing values of civilization among high school students in Buraydah city form the teachers' perspective. To achieve this objective, the study followed the descriptive method. A questionnaire, consisting of 35 items and distributed over 3 dimensions, was designed to collect relevant data. The questionnaire was administered to a random sample of 300 teachers, who represented 30% of the whole population. Major findings revealed that the degree of practicing the role of developing civilization values by teachers was high at a mean of (3.96). Further, there were no statistically significant differences attributed to the study level. However, statistically significant differences were found at (α≥ 0.05) in the participants' responses regarding their assessment of the teacher's role in developing civilization values attributed to major in favor of education major. Finally, there were no statistically significant differences with regard to the variables of years of experience and training courses.
Evaluation of the Content of Math Courses at the Faculty of Education- Sana’a University in light of Quality Standards
Authors: Abdullah Al Haddad Dr. Fawzi 
Published: July 2022

This study aimed to examine the availability of quality standards pertinent to mathematical thinking styles, objectivity and creative problem solving in math courses at the Faculty of Education, Sana’a University. To achieve this, the descriptive analytical method was used. Checklists for analyzing the math content were developed and a questionnaire was used to check their validity. The instuments were applied to a smple of four courses of the 3rd and 4th levels. The study results revealed that the total weights of deductive and inductive mathematical thinking were 69.66% and 30.34% respectively. This percentage covered the quality of thinking styles being comprehensively represented in all the courses as follows: correlational thinking style, the highest type, scored 65.43%; thinking style using symbols scored 20.61%; other styles of mathematical thinking were represented in the content by varied percentages, ranging from 0% to 10.78%. These other styles include reflective, systematic, strategic, critical, accurate and creative thinking styles. The course content lacked creative problem solving questions. Further, the results of the Chi-square test showed statisitically significant differences at 0.01 regarding the quality standards of mathematical thinking, objectivity and creative problem solving. This means that the courses do not achieve the quality standards of developing thinking styles and creative problem solving among student-teachers.
A ANTROPOMORFIZAÇÃO DOS ANIMAIS DOMÉSTICOS E O REGISTRO DE “NASCIMENTO” E GUARDA EM CARTÓRIO COMO (MAIS) UMA EXPRESSÃO DA FAMÍLIA MULTIESPÉCIE
Authors: Hegele Bolson Simone , Hegele Bolson Solano 
Published: July 2022

O fenômeno da antropomorfização dos animais domésticos é uma realidade hodierna e são várias suas manifestações, desde a opção por alimentação vegana, passando pela escolha do “guarda-roupa e vestuário”, a medicalização de doenças, até o registro dos pets no cartório do Registro de Títulos e Documentos. Essa “humanização” ou o ato de conferir aos pets características e sentimentos humanos se acentuou nas últimas décadas por razões ligadas à própria subjetividade dos tutores, à mudança de paradigma em relação aos animais – de coisa, propriedade ao afeto - e à constituição de um novo tipo de família. O presente artigo defende que a antropomorfização, não obstante os seus excessos, é própria da sociedade humana pós-moderna e contribui para que se estabeleça a família multiespécie, considerando-se uma concepção de antropocentrismo “alargado” em relação aos animais não humanos. No campo jurídico civil-registral, a possibilidade do registro dos animais domésticos em documento realizado junto ao Registro de Títulos de Documentos reconhece expressamente a família multiespécie, o que se constitui em inegável avanço jurídico. O PetLegal, lançado em agosto de 2017, é um procedimento extrajudicial que serviu de modelo ao Registro de Títulos e Documentos, em que há a emissão de uma “certidão de nascimento e guarda” para os animais domésticos, na qual constarão os dados de identificação do animal e que servirá em eventual busca de animais perdidos ou roubados ou como prova em processos judiciais pela guarda do pet. Trata-se de um meio de prova legal dos direitos dos tutores e, junto com a recente Lei 14.064/20, estabelece maior proteção aos animais no direito brasileiro, enquanto não se reconhece - caminho irreversível – a personalidade jurídica aos animais.
Mitigating Water Production from High Viscosity Oil Wells in Unconsolidated Sandstone Formations
Authors: Al-Rashidi Hamad , Hussein Mahmoud Reda , Erhamah Abdulaziz , Malik Satinder , AL-Hajri Abdulrahman , Salehi Nazanine , Omonte Rossi German , Zaitoun Alain , Almeida Dwane 
Published: July 2022

Summary
Large reserves of high-viscous oil in Kuwait call for improved oil recovery scenarios. In Kuwaiti unconsolidated sandstone formations, the sandstone intervals represent extensive reservoir intervals of sand separated by laterally extensive nonreservoir intervals that comprise finer-grained argillaceous sands, silts, and muds. The reservoir is shallow with high permeability (above 1,000 md) and under bottom aquifer pressure support. Due to strong viscosity contrast between oil and water, after breakthrough, the water cut rises quickly, resulting in strong loss of production efficiency. Mitigating water production is thus mandatory to improve production conditions.
The candidate wells have two to three open intervals in different rock facies with comingle production. The total perforated length is between 38 and 48 ft. Production is through progressing cavity pumps (PCP) at a rate of around 300 B/D, and basic sediment and water is between 71 and 87%.
The technology applied utilizes pregelled size-controlled product [small microgels (SMG Microgels)] having relative permeability modification (RPM) properties; that is, inducing a strong drop of relative permeability to water without affecting oil relative permeability. The size is chosen to selectively treat the high-permeability water producing zones while preserving the lower-permeability oil zones. The chemical can also withstand downhole harsh conditions such as salinity of around 170,000 ppm and presence of 2% H2S.
The treatment consisted of bullhead injection of 300 bbl of pregelled chemical through-tubing. The first results seem very favorable, since for two wells, the water cut has dropped from 80 to 40% with almost same gross production rate. The incremental oil is more than 100 BOPD. The third well did not show marked change after water system operation (WSO) treatment. The wells are under continuous monitoring to assess long-term performance.
Such result, if confirmed, may lead to high possibilities for the improvement of heavy oil reservoir production under aquifer support by mitigating water production with simple chemical bullhead injection.
A target engagement assay to assess uptake, potency and retention of antibiotics in living bacteria
Authors: Fanti Rebeka , Vasconcelos Stanley , Catta-Preta Carolina , Sullivan Jaryd , Riboldi Gustavo , Reis Caio dos , Ramos Priscila , Edwards Aled M. , Behr Marcel , Couñago Rafael M. 
Published: July 2022

Abstract
New antibiotics are urgently needed to counter the emergence of antimicrobial resistant pathogenic bacteria. A major challenge in antibiotics drug discovery is to turn potent biochemical inhibitors of essential bacterial components into effective antimicrobials. This difficulty is underpinned by a lack of methods to investigate the physicochemical properties needed for candidate antibiotics to permeate the bacterial cell envelope and avoid clearance by the action of bacterial efflux pumps. To address these issues, here we used a target engagement assay to measure the equilibrium and kinetics binding parameters of antibiotics targeting dihydrofolate reductase (DHFR) in live bacteria. We also used this assay to identify novel DHFR ligands having antimicrobial activity from a library of compounds. We validated this approach using the Gram-negative bacteria Escherichia coli and the emerging human pathogen Mycobacterium abscessus. We expect the use of target engagement assays in bacteria to expedite the discovery and progression of novel, cell-permeable antibiotics with on-target activity.
Effect of sevoflurane on serum CK-MB levels after percutaneous coronary stent placement: prospective randomized clinical trial
Authors: Rossi Ronaldo , Nigro Caetano , Braga Sergio Luis Navarro , Sousa Amanda , Feres Fausto , Costa Jose de Ribamar 
Published: July 2022

Abstract
Background: Markers of myocardial injury, such as creatine kinase myocardial band (CK-MB mass), are elevated in up to 30% of patients undergoing percutaneous coronary intervention (PCI) with stent deployment. This elevation represents myocardial injury that can impact the patient in the long term, including the risk of death. Sevoflurane, an inhaled anesthetic, may have cardioprotective properties, benefiting patients undergoing PCI.Methods: Randomized (1:1), double-blind, placebo-controlled trial enrolling patients with CAD eligible for PCI. The primary objective was to compare serum CK-MB mass raise in both groups. Additionally, we compared substantial elevations in CK-MB mass (defined as > 5x the upper limit of normal), length of stay in the ICU and in hospital, and one-year mortality.Results: 1,254 patients were randomized to receive sevoflurane (2% inspired fraction) or placebo (oxygen alone) for 30 minutes prior to PCI. Patients having experienced acute MI within 72h and those with stents in SVG were excluded. Sevoflurane was unable to promote cardioprotection, as determined by CK-MB mass levels (sevoflurane group: 2.52 ± 9.64; control group: 1.84 ± 8.58; p = 0.32). No effect was noticed on the reduction among patients who increase marker levels (prevalence of increase in CK-MB mass greater than the upper limit of normality = 30.8% in the sevoflurane group and 28.9% in the control group; p = 0.33; 4.6% vs. 3.1%, respectively, for increases 5x above the upper limit of normality [p = 0.21]).Conclusion: Sevoflurane failed to reduce myocardial injury after PCI. Therefore, its usage should not be routinely recommended.
Is contralateral femoral neck-shaft angle predictive of timing of subsequent hip fracture?
Authors: Wahab Ezanul Harriz Abd , Downey Colum , Lawlor Sophie , O'Kelly Patrick , Shortt Conor , Quinlan John 
Published: July 2022

Abstract
IntroductionIn 2019, research showed that in the six acute adult Dublin hospitals, 1 in 11 patients with fragility hip fracture sustained a second contralateral hip fracture. These have implications of additional patient morbidity and cost to the health service. Relationship of the contralateral femoral neck-shaft angle (NSA) and timing to the second hip fracture have not been established previously. Our study aimed to establish the relationship of the contralateral femur NSA in patient who already sustained a fragility hip fracture and determine if we could predict the timing of the second hip fracture.MethodsA 7 year single institution retrospective cohort study of patients that presented with second fragility hip fracture from 2013-2019 were reviewed. Exclusion criteria are patients who were aged less than 60 years old, high energy injuries, or had a peri-prosthetic fractures. Plain films anteroposterior (AP) pelvis radiographs were reviewed on the National Integrated Medical Imaging System (NIMIS) McKessons. NSA of the contralateral hip prior to second hip fracture were measured with a standardized method with the TraumaCAD software. Correlation analysis performed with Stata SE statistical software.Results and discussionContralateral NSA is not statistically significant in predicting the timing to second hip fracture. Causes of fragility hip fracture and subsequent second hip fracture are multifactorial and multidisciplinary approach such as fracture liaison services are essential to improve the prevention and treatment of such injuries.
XRD, structural, optical, electrical and magnetic properties of ZnO nanoparticles incorporated with Cr as a promising material for different applications
Authors: Moussa Nasser , Ebrahim F.M. , Adly Karam , Hassaan M.Y 
Published: July 2022

Abstract
This work was suggested to study the impact of Cr ions doping on the structural, optical, electrical and magnetic behavior of ZnO nanoparticles (NPs). The Zn1-xCrxO (with 0 ≤ x ≤ 0.14 wt. %) samples were fabricated by the co-precipitation technique. The obtained samples were characterized by the X-ray diffraction (XRD) technique, (FTIR) spectroscopy and UV-vis spectrophotometer. XRD patterns showed the presence of wurtzite (hexagonal) crystal structure with secondary phase formation in all doped samples. Lattice parameter (a) decreased and grain size decreased with increasing Cr concentration. The FTIR spectroscopy spectra showed the existence of chromium ions in the structure of ZnO nanoparticles. UV-vis spectra showed a red shift in the centers of the absorption bands. The energy band gab was found to be increased from 3.84 to 4.02 eV with increasing Cr content. The dielectric parameters such as, dielectric constant (ϵ') and dielectric loss (tan δ), were investigated as a function of frequency and Cr doping content. The results showed increasing values of ϵ' at lower frequency especially with high Cr doping content, whereas tan δ gives a higher value for the blank sample at a lower frequency and decreased as the doping of Cr concentration increased. The ac conductivity (σac) for Cr doping samples showed increasing values, especially the sample of 0.14 wt. % Cr concentration. In addition, the Cr doped ZnO nanoparticles exhibited a ferromagnetic behavior at room temperature. All the results obtained from the different techniques were considered promising for different applications.
Epidemiology of interstitial lung disease in patients with metastatic breast cancer at baseline and after treatment with HER2-directed therapy: a real-world data analysis
Authors: Law Jeanna Wallenta , Campbell Alicyn , Weller Colin , Johanson Colden , Broome Ronda , Piault Elisabeth , Izano Monika , Schrag Andrew , Tran Mary , Brown Thomas D. , Kaplan Henry G. 
Published: July 2022

Abstract
Purpose: Using real-world data, interstitial lung disease (ILD) prevalence before and after HER2-directed therapy was estimated. Potential ILD risk factors in patients receiving HER2-directed therapy for metastatic breast cancer (mBC) were evaluated. Methods: Adults with HER2-directed therapy for mBC initiated between September 25, 1998 and February 22, 2020 were included. ILD was defined broadly as one or more of 64 lung conditions. Patients were followed until incident ILD, death, last contact, or study end. Results: 533 patients were identified with median age at mBC of 57, 51% had de novo mBC, 43% ever smokers, 30% had lung metastases, 9% thoracic radiation, 6% chronic obstructive pulmonary disease (COPD), and 16% had prevalent ILD. ILD cumulative incidence at one year was 9% (95% CI: 6%, 12%), with a median follow-up of 23 months. Smoking (HR = 2.2, 95% CI: 1.1, 4.8) and Black/African-American race (HR = 3.4, 95% CI: 1.6, 7.5) were significantly associated with ILD; HRs for pre-existing lung conditions (HR = 1.8, 95% CI: 0.9, 3.8) and thoracic radiation (HR = 2.3, 95% CI: 0.8, 7.1) were not statistically significant. Prevalent ILD was associated with 13-fold greater occurrence of incident ILD. 85% of patients with prevalent or incident ILD were symptomatic. Conclusions: This real world population of patients with mBC had a high prevalence of ILD prior to HER2 directed therapy, reflecting the multifactorial causation of interstitial lung changes. The cumulative incidence of ILD in patients receiving HER2 directed therapy for mBC augment prior reports. Symptomatic presentation suggests an opportunity for early intervention.
Multidrug Resistant Escherichia Coli Isolates Expresses Several Virulence Genes in Poultry Samples From Jos, Nigeria.
Authors: Agusi Ebere Roseann , Kabantiyok D , Mkpuma Nicodemus , Atai Rebecca Bitiyong , Okongwu-Ejike Chidinma , Bakare Ebun Lydia , Budaye James , Sule Kabiru Garba , Rindaps Rindah Joy , James Gyallak Kingsley , Audu Benshak. J. , Agada Godwin , Meseko Clement. A. 
Published: July 2022

Abstract
The phenomenon of bacteria resistance to three or more antibiotic classes has been defined as multidrug resistance (MDR). Antimicrobial resistance is increasingly becoming a global health problem. The aim of this study was to report MDR Escherichia coli prevalence, resistant and virulence genes from poultry in Jos South LGA of Plateau State. Out of 179 cloacal swabs collected from both local and exotic breeds, 99.44% (178/179) were positives for Escherichia coli. Of 178 samples identified culturally 99.44% (177/178) were confirmed to be positive for Escherichia coli with molecular weight of 401 bp. PCR assay also confirmed the presence of genes associated with resistance to TetA, Sul1, AmpC and GyrA. 81.92% (145/177) of the isolates were resistant to Tetracycline, 80.22% (142/177) to Quinolone, 69.50% (123/177) to Sulphanomide and 66.10% (117/177) to Ampicillin. 18 isolates that showed resistance for up to four different antibiotics were further analysed by Multiplex PCR to detect Eae, HlyA, RfbE, FliC and Stx2 virulence genes. 44.4% (15/18) of the isolates were positive for Eae gene, 27.7% (5/18) for Stx2, 22.20% (4/18) for Rfbe gene, 5.5% (1) for Hlya gene, and none for FliC gene. Our results showed high antibiotic resistance, virulent genes and significant levels of MDR in Escherichia coli from poultry. This study underscores the need for antimicrobial stewardship in poultry because of its implication for food safety and health. This is important because poultry farmers form a significant group of small holder farmers in Nigeria.