bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cyberloafing behaviours in nursing: The role of nursing stressors
Authors: Alqahtani Naji , Innab Adnan , Alammar Kamila , Alkhateeb Reham , Kerari Ali , Alharbi Mohammad 
Published: June 2022

AbstractAimTo assess the prevalence of minor and serious cyberloafing behaviours among nurses and examine the impact of the nursing stressors on nurses' cyberloafing behaviours.BackgroundCyberloafing could have a negative influence on employees' job performance, but it also has been argued that it could serve as a coping mechanism to deal with stressful work environments.DesignA cross‐sectional descriptive, correlational design.MethodsData were collected between September and December 2020 from a convenience sample of staff nurses (N = 291) providing care at a tertiary hospital in Saudi Arabia. Sample characteristics, nursing stressors and cyberloafing behaviours information were collected using self‐reported questionnaires. Descriptive, bivariate and multivariate analyses were performed.FindingsNurses in Saudi Arabia exhibited low levels of minor and serious cyberloafing behaviours. However, they engaged more frequently in minor cyberloafing behaviours more than serious cyberloafing behaviours. Stressors and Internet usage frequency influenced the frequency of minor and serious cyberloafing behaviours. Level of education and nationality impacted serious cyberloafing behaviours only.ConclusionNursing stressors were associated with cyberloafing behaviours. Other studies on cyberloafing and job stress yielded inconsistent results. Efforts should be taken to avoid the adverse effects of cyberloafing by establishing a clear policy on using the advanced technology for non‐work purposes.
Evaluation of distinct modes of oxidative secondary injury generated in heat-treated cells of Escherichia coli with solid/liquid and complex/semi-synthetic media sets
Authors: Vo Khanh C. , Wada Akihiro , Iwata Riyo , Asada Ryoko , Sakamoto Jin J. , Furuta Masakazu , Tsuchido Tetsuaki 
Published: June 2022

Abstract

Aims
To characterize and evaluate oxidative secondary injury generated in heat-treated Escherichia coli cells during recovery cultivation either on agar or in a broth of a semi-synthetic enriched M9 (EM9) medium and a complex Luria broth (LB) medium with different types of antioxidants.

Methods and Results
E. coli cells grown in the EM9 and LB broth were heated at 50°C in a buffer (pH 7.0). Heated cells were recovered on the same kind of agar medium as that used for growth, with or without different antioxidants. Although these antioxidants mostly protected the cells from oxidative secondary injury on the recovery media, sodium thiosulphate and sodium pyruvate were most protective on EM9 and LB agars, respectively. Determination of viability using the most probable number and growth delay analysis methods showed significant reductions in the protective effects of antioxidants in the EM9 and LB media.

Conclusion
Oxidative secondary injury generated in heated E. coli cells was found to be qualitatively and quantitatively diverse under cellular and environmental conditions.

Significance and impact of the study
Our results suggest that different modes of oxidation should be considered in viability determination and injured cell enumeration of heat-treated cells.
Factors associated with uncontrolled blood pressure in hypertensive Brazilians
Authors: Araújo Thayza de Paula , Borges Lucas Gabriel Sulino , Barroso Weimar Kunz Sebba , Brandão Andrea Araújo , Barbosa Eduardo Costa Duarte , Feitosa Audes Diógenes M , Malachias Marcus Vinícius Bolivar , Mota Gomes Marco , Amodeo Celso , Povoa Rui Manoel dos Santos , Jardim Paulo César Brandão Veiga , Lopes Renato D. , Batista Sandro Rogério Rodrigues , Vitorino Priscila Valverde de Oliveira ,   the researchers of Study I RBH
Published: June 2022

AbstractUncontrolled hypertension has a high prevalence and is related to numerous negative health outcomes. This study aimed to investigate the factors associated with the lack of blood pressure control in hypertensive Brazilians treated in public and private services. This is an analytical, multicentric, and national cross‐sectional study, carried out with adult hypertensive patients, monitored in 45 outpatient clinics (September 2013 to October 2015) in a prospective record interview, clinical, and anthropometric assessment. Outcome variables included uncontrolled pressure (systolic blood pressure ≥ 140 mmHg and/or diastolic blood pressure ≥ 90 mmHg). Simple and multiple logistic regression analyses were performed. Two thousand six hundred forty‐three participants were assessed with a mean age of 61.6 ± 11.9 years, 55.7% of women, and 46.4% with uncontrolled blood pressure (BP). The following were associated with uncontrolled BP: age over 60 years (OR: 1.31 [1.11–1.55]); practice of irregular physical activity (OR: 1.28 [1.06–1.55]); attending the emergency room for hypertensive crises in the last six months (OR: 1.80 [1.46–2.22]); increased body mass index (OR: 1.02 [1.01–1.04]); low adherence to drug treatment (OR: 1.22 [1.04–1.44]) and menopause (OR: 1.36 [1.07–1.72]). The following were negatively associated: fruit consumption (OR: 0.90 [0.85–0.94]); presence of dyslipidemia (OR: 0.75 [0.64–0.89]), acute myocardial infarction (OR: 0.59 [0.46–0.76]), and peripheral arterial disease (OR: 0.52 [0.34‐0.78]). Factors associated with difficult‐to‐control blood pressure are the same that increase the risk for hypertension, while the presence of atherosclerotic disease and its outcomes were associated with better control.
Annexin‐1 is an oncogene in glioblastoma and causes tumour immune escape through the indirect upregulation of interleukin‐8
Authors: Chen Rui , Chen Chengqi , Han Na , Guo Wenjing , Deng Hui , Wang Yali , Ding Yanpeng , Zhang Mengxian 
Published: June 2022

AbstractAnnexin‐1 (ANXA1) is widely reported to be deregulated in various cancers and is involved in tumorigenesis. However, its effects on glioblastoma (GBM) remain unclear. Using immunohistochemistry with tissue microarrays, we showed that ANXA1 was overexpressed in GBM, positively correlated with higher World Health Organization (WHO) grades of glioma, and negatively associated with poor survival. To further explore its role and the underlying molecular mechanism in GBM, we constructed ANXA1shRNA U87 and U251 cell lines for further experiments. ANXA1 downregulation suppressed GBM cell proliferation, migration, and invasion and enhanced their radiosensitivity. Furthermore, we determined that ANXA1 was involved in dendritic cell (DC) maturation in patients with GBM and that DC infiltration was inversely proportional to GBM prognosis. Considering that previous reports have shown that Interleukin‐8 (IL‐8) is associated with DC migration and maturation and is correlated with NF‐κB transcriptional regulation, we examined IL‐8 and p65 subunit expressions and p65 phosphorylation levels in GBM cells under an ANXA1 knockdown. These results suggest that ANXA1 significantly promotes IL‐8 production and p65 phosphorylation levels. We inferred that ANXA1 is a potential biomarker and a candidate therapeutic target for GBM treatment and may mediate tumour immune escape through NF‐kB (p65) activation and IL‐8 upregulation.
Publishing clinical prActice GuidelinEs (PAGE): Recommendations from editors and reviewers
Authors: Yang Nan , Zhao Wei , Qi Wenan , Yao Chen , Dong Chongya , Zhai Zhenguo , Chen Tong , Liu Enmei , Li Guobao , Long Youlin , Wang Xinyi , Wang Zijun , Lei Ruobing , Zhou Qi , Chen Yaolong , Du Liang ,   TERM Working Group
Published: June 2022

AbstractTransparency Ecosystem for Research and Journals in Medicine (TERM) Working Group summarized the essential recommendations that should be considered to review and publish a high‐quality guideline. These recommendations from editors and reviewers included the ten components of essential requirements: systematic review of existing relevant guidelines, guideline registration, guideline protocol, stakeholders, conflicts of interest, clinical questions, systematic reviews, recommendation consensus, guideline reporting, and external review. TERM Working Group abbreviates them as PAGE (essential requirements for Publishing clinical prActice GuidelinEs), recommends guideline authors, editors, and peer reviewers use them for high‐quality guidelines.
Periodic operation as an alternative to intensify the hydration process of common beans (Phaseolus vulgaris)
Authors: Carvalho Vanessa Souza , de Oliveira Lucas Carvalho , de Matos Jorge Luiz Mário , Jorge Regina Maria Matos 
Published: June 2022

AbstractThe goal of this work was to improve upon already existing hydration kinetic studies for the common bean (Phaseolus vulgaris) by evaluating periodic action by means of temperature modulation as a method for intensifying the process, a theme that has been little explored in the literature. Bean grains were hydrated for 10 h under isothermal operation at 30, 40, and 50°C, as well as under periodic operation at an average temperature of 40°C, with an amplitude of 10°C and a period of 5 min. Peleg and Diffusion models were used to fit the hydration kinetic curves from the experimental data, which exhibited a satisfactory quality of fit for all conditions. The values of the model parameters revealed that hydration under periodic operation exhibits a greater rate and water absorption capacity as compared to isothermal operations, providing the same moisture gain as hydration at 40°C with a process time reduction of 65%. DSC analysis revealed that starch extracted from in natura beans undergoes gelatinization at 74.6°C, a temperature not used in the hydration tests; therefore, the starch structure was preserved, as shown by the images recorded using SEM. The study made it possible to confirm that periodic operation under the evaluated conditions may be advantageous for use in bean hydration, since a reduction in processing time results in savings of both energy and water. Thus, this academic knowledge can be useful both for well‐established industries, such as ready‐to‐eat beans, and for the development of new products.Practical ApplicationsThe common bean (Phaseolus vulgaris) is one of the most commonly consumed legumes worldwide, being an important source of protein. Beans are usually hydrated in order to reduce their antinutrient content and facilitate subsequent processes (such as cooking, germination, etc.), although this process is time‐consuming and requires a great deal of water and energy consumption. In this sense, the periodic operation can enable the intensification of the bean hydration process, requiring less time to reach a specified moisture content and consequently providing an increase in processing capacity, with less water consumption and energy costs. Currently, there are several industries that sell ready‐to‐eat beans (whether canned, vacuumed, or in plastic packaging) that use the grain hydration stage, and therefore could benefit from this innovative method. In addition, the academic knowledge generated also supports the development of new products.
The perceived costs and benefits of mentoring college students with intellectual disability on stereotype consistent and inconsistent tasks
Authors: McManus J. L. , Reed C. , Saucier D. A. 
Published: June 2022

AbstractBackgroundAccording to the stereotype content model, individuals with intellectual disability are perceived as having greater warmth‐related traits (e.g. sociable and humorous) and fewer competence‐related traits (e.g. independence and intelligence).MethodsWe examined college students' perceived costs and benefits of mentoring peers with intellectual disability on stereotype‐consistent (i.e. socially oriented) or inconsistent (i.e. academically oriented) tasks. Participants read about peer mentoring programmes that helped college students with or without intellectual disability on socially or academically oriented tasks before reporting their perceived costs and benefits of peer mentoring.ResultsMentoring students with intellectual disability was associated with greater benefits (i.e. connectedness between mentors and students, student utility and mentor benefits) on academically oriented tasks but greater costs for mentors on socially oriented tasks. Additionally, participants reported that they would experience greater positive feelings if they were to mentor a student with an intellectual disability. However, the perceived benefits to the student and some costs (i.e. discomfort, paternalism and costs to student) were not influenced by whether the student had an intellectual disability and the type of mentoring task.DiscussionResults indicate individuals find greater rewards working with individuals with intellectual disability on stereotype‐inconsistent tasks and offer suggestions for postsecondary education peer mentoring programmes.
Multilayered silicone foam dressings potentially used for preventing recurrence of pressure injuries: A bench‐to‐clinical bedside study
Authors: Kohta Masushi , Urai Tamae , Saad Supriadi Syafiie , Sugama Junko 
Published: June 2022

AbstractAimThis study aimed to evaluate the use of multilayered silicone foam dressings for preventing pressure injury recurrence by reducing friction, pressure, and shear force at skin sites where previous pressure injuries closed.MethodsA bench‐to‐clinical bedside investigation was conducted. In the bench, three multilayered silicone foam dressings were assessed. The simulated skin‐shearing test consisted of a weight, a polyurethane‐based skin model containing a three‐axis tactile sensor, dressings, a table covered with bedsheets, and a mechanical tester. The mechanical tester simultaneously measured the interface friction force and internal shear force and pressure continuously during skin model movements. No‐dressing was used as a negative control. In clinical bedside assessments, a multilayered silicone foam dressing with lower friction and shear force was applied to two bedridden patients. Photographs and ultrasound images were used to assess the recurrence of pressure injury.ResultsThe dressings significantly reduced friction, pressure, and shear force compared with these parameters in the negative control. No significant differences in the shear forces between the dressings were observed. One clinical case did not develop a new pressure injury reaching the dermis. However, the second case developed a new pressure injury within one month after the first pressure injury closed.ConclusionOur bench‐to‐clinical bedside study revealed that multilayered silicone foam dressings can potentially prevent pressure injury recurrence.
Significant paradigm of beauty ecosystem after COVID‐19 pandemic in Republic of Korea
Authors: Kim Minchae , Kwon Ki Han 
Published: June 2022

AbstractBackgroundThe beauty industry, one of the face‐to‐face the essential industries in the COVID‐19 pandemic, has been hit hard.AimsWe present the current state of the beauty ecosystem in the corona pandemic and the future direction of the beauty industry after COVID‐19.MethodsThis review paper is a literature review, and a descriptive review approach was used in this study. A total of 100–150 references were selected using representative journal search sites such as PubMed, Google Scholar, Scopers, Research Gate, and RISS, and a total of 24 papers were finally selected as of 2017–2022 using PRISMA flow diagram.ResultsIn Korea, the beauty industry, which is essential to face‐to‐face due to COVID‐19, was hit hard. The contraction of consumer sentiment led to a drop in sales. The online market has become more active as offline activities have declined sharply. Even during the COVID‐19 era, the Republic of Korea is an IT powerhouse. With the widespread use of K‐drama and K‐pop, the interest in Korean beauty and fashion has increased rapidly throughout the world. Therefore, K‐Makeup, hair, skincare, and nailcare are all the rage through YouTube. Predict new changes in the Korean beauty industry market, which is the center of K‐beauty and K‐cosmetics. As a leader in the beauty industry, the Republic of Korea will present the sustainability of the beauty ecosystem and the direction of its development.
Patient and carer experience of living with a pressure injury: A meta‐synthesis of qualitative studies
Authors: Burston Adam , Miles Sandra J. , Fulbrook Paul 
Published: June 2022

AbstractIntroductionPressure injuries are a significant cause of harm, contributing to increased mortality and financial burden on the healthcare system. Significant research on pressure injury risk assessment, prevention and treatment exists, but limited research exploring the patient and carer experience of living with pressure injury.AimsThe aim of this meta‐synthesis was to describe the patient and carer experience of living with a pressure injury.DesignMeta‐synthesis.MethodsA prospective review protocol was registered, and systematic search conducted across five electronic databases. The PRISMA 2020 checklist for reporting systematic reviews was used. Two reviewers independently undertook screening and review of articles, using the CASP checklist for evaluating qualitative research. A meta‐synthesis using thematic content analysis was undertaken.ResultsTwelve studies met the inclusion criteria. Meta‐synthesis led to the construction of three primary themes: loss of autonomy and independence, psychological effects, and adjustment. Within these primary themes, sub‐themes of dependence, social isolation and social avoidance behaviours, feelings and emotions, loss, managing, physical consequences, service provision, and functional challenges, were identified.ConclusionThe psychology and mindset of those involved, and support to navigate the challenges that arise are two unique and clinically relevant categorisations to guide provision of pressure injury care. Adaptation to a pressure injury is multi‐faceted and contextual, challenges to adaptation create additional psychological burden. Interventions encompassing all facets of the experience are necessary. Current research into experiences is limited, and further research to support interventions is necessary.
Pharmacological potential of seaweed-associated heterotrophic Firmicutes
Authors: Asharaf S. , Chakraborty K. 
Published: June 2022

Abstract
Seaweed-associated bacterial symbionts are sources of potential pharmacological properties. The present study resulted in the culture-dependent isolation of bioactive heterotrophs belonging to the bacterial phylum Firmicutes, which were dominated more than 30% of the 127 cultivable isolates, amongst which 23 of them showed potential antimicrobial activities against a wide range of pathogens. The symbionts isolated from the seaweed Sargassum wightii showed significant bioactivity. Those were characterized as Bacillus safensis MTCC13040, B. valismortis MTCC13041, B. velezensis MTCC13044, B. methylotrophicus MTCC13042, Oceanobacillus profundus MTCC13045, B. tequilensis MTCC13043, and B. altitudinis MTCC13046. The organic extracts of the studied isolates showed potential antimicrobial properties against methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococci (minimum inhibitory concentration 6·25–12·5 μg ml−1). The organic extract of B. altitudinis MTCC13046 displayed significantly greater radical quenching ability (IC90 133 μg ml−1, P &lt; 0·05) other than attenuating hydroxymethyl glutaryl coenzyme A reductase (IC90 10·21 μg ml−1, P &lt; 0·05) and angiotensin-converting enzyme-1 (IC90 498 μg ml−1, P &lt; 0·05) relative to other studied heterotrophs. The organic extract of B. tequilensis MTCC13043 displayed significantly greater attenuation potential against pro-inflammatory 5-lipooxygenase (IC90 5·94 μg ml−1, P &lt; 0·05) and dipeptidyl peptidase-4 (IC90 271 μg ml−1, P &lt; 0·05). The seaweed-associated B. altitudinis MTCC13046 and B. tequilensis MTCC13043 could be used to develop promising pharmacological leads.
Transforaminal Endoscopic Lumbar Discectomy for Lumbosacral Junction Adolescent Lumbar Disc Herniation with High Iliac Crests
Authors: Mao Lu , Wang Kun , Huang Yong , Wang Feng , Zhang Rui , Zhu Bin , Wu Xiaotao 
Published: June 2022

AbstractObjectiveTo investigate the clinical results of transforaminal endoscopic lumbar discectomy for lumbosacral junction adolescent lumbar disc herniation with high iliac crest.MethodsFrom February 2014 to September 2020, a retrospective analysis of 96 patients less than 21 years old with intervertebral disc herniation was carried out. We enrolled 44 patients diagnosed with lumbosacral junction disc herniation with high iliac crest who required transforaminal endoscopic lumbar discectomy. Pain in the back and the lower extremity was scored on Numeric Rating Scales (NRS) scores. Patient outcomes were graded as excellent, good, fair, and poor using modified MacNab criteria. The NRS scores before and after the operation were compared using the Wilcoxon two‐sample test.ResultsThere were 30 male patients and 14 females. One patient underwent repeat surgery for an intervertebral disc pseudocyst. The NRS scores decreased significantly in both early and late follow‐up evaluations (p < 0.05). At the last follow‐up, 42 patients (95.45%) had an excellent outcome, one patient (2.27%) had a good outcome, and one patient (2.27%) had a fair outcome. The overall success rate was 97.7%.ConclusionThis study's data suggest that targeted individualized foraminoplasty can effectively overcome the lumbosacral anatomical obstacles, and transforaminal endoscopic lumbar discectomy is an effective and valid option for lumbosacral junction adolescent lumbar disc herniation with high iliac crest.