bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stepwise Energy Transfer: Near‐Infrared Persistent Luminescence from Doped Polymeric Systems
Authors: Lin Faxu , Wang Haiyang , Cao Yifeng , Yu Rujun , Liang Guodong , Huang Huahua , Mu Yingxiao , Yang Zhiyong , Chi Zhenguo 
Published: February 2022

AbstractOrganic near infrared (NIR) persistent‐luminescence systems with bright and long‐lived emission are highly valuable for applications in communication, imaging, and sensors. However, realizing these materials (especially lifetime over 0.1 s) is a challenge, mainly because of non‐radiative quenching of their long‐lived excitons. Herein, a universal strategy of stepwise Förster resonance energy transfer (FRET) for a bright NIR system with remarkable persistent luminescence (up to 0.2 s at 810 nm) is presented, based on a new triphenylene‐dye‐doped polymer (triphenylene‐2‐ylboronic acid@poly(vinyl alcohol) (TP@PVA)) with a persistent blue phosphorescence of 3.29 s. This persistent NIR luminescence is demonstrated for application not only in NIR anti‐counterfeiting but also NIR bioimaging with penetrating a piece of skin as thick as 2.0 mm. By co‐doping a red dye (such as Nile red) and an NIR dye Cyanine 7 (Cy7) into this doped PVA film, the shortage of spectral overlap between TP emission and Cy7 absorbance is successfully solved, through a stepwise FRET process involving triplet to singlet (TS)‐FRET from TP to the intermediate red dye and then singlet to singlet (SS)‐FRET to Cy7. It is noted that the efficiency of the upper TS‐FRET is enhanced significantly by the lower SS‐FRET, leading to high efficiencies for the continuous FRETs.
Bioactive Materials Promote Wound Healing through Modulation of Cell Behaviors
Authors: Li Ruotao , Liu Kai , Huang Xu , Li Di , Ding Jianxun , Liu Bin , Chen Xuesi 
Published: February 2022

AbstractSkin wound repair is a multistage process involving multiple cellular and molecular interactions, which modulate the cell behaviors and dynamic remodeling of extracellular matrices to maximize regeneration and repair. Consequently, abnormalities in cell functions or pathways inevitably give rise to side effects, such as dysregulated inflammation, hyperplasia of nonmigratory epithelial cells, and lack of response to growth factors, which impedes angiogenesis and fibrosis. These issues may cause delayed wound healing or even non‐healing states. Current clinical therapeutic approaches are predominantly dedicated to preventing infections and alleviating topical symptoms rather than addressing the modulation of wound microenvironments to achieve targeted outcomes. Bioactive materials, relying on their chemical, physical, and biological properties or as carriers of bioactive substances, can affect wound microenvironments and promote wound healing at the molecular level. By addressing the mechanisms of wound healing from the perspective of cell behaviors, this review discusses how bioactive materials modulate the microenvironments and cell behaviors within the wounds during the stages of hemostasis, anti‐inflammation, tissue regeneration and deposition, and matrix remodeling. A deeper understanding of cell behaviors during wound healing is bound to promote the development of more targeted and efficient bioactive materials for clinical applications.
Temperature Modulating Fermi Level Pinning in 2D GeSe for High‐Performance Transistor
Authors: Muhammad Zahir , Li Yuliang , Abbas Ghulam , Usman Muhammad , Sun Zhe , Zhang Yue , Lv Ziyu , Wang Yan , Zhao Weisheng 
Published: February 2022

Abstract2D layered germanium selenide (GeSe) material possesses in‐plane anisotropy because of low‐symmetry crystal structure with a new degree of freedom for enhanced optical and electronic properties. However, their systematic vibrational and electronics properties are still under the scope to study. Herein, the vibrational properties of GeSe sheets are studied by Raman spectroscopy. Whereas, the temperature‐dependent electronic band structure is studied using angle‐resolved photoemission spectroscopy (ARPES) combined with density functional theory calculations. Moreover, the field‐effect transistor (FET) is fabricated on a few‐layer GeSe with high performance. The vibrational modes and demonstrates linear softening as the temperature increases, with temperature coefficient value associated by anharmonic phonon–phonon/electron coupling. Besides, the enhanced dielectric screening effect of long‐range Coulomb and interlayer interaction is observed from bulk to monolayer. Similarly, ARPES results further show Fermi level movement toward the valance band as increased temperature represents hole doping to pining the Fermi level, which indicates superior carrier concentration for electronic properties. The fabricated FET device on six layers GeSe exhibits high carrier mobility of 52.89 cm2 V−1 s−1 with an on/off ratio above 4 × 105 at room temperature, while it decreased below the room temperature. Our results provide the important figure of merit for GeSe‐based novel nanoelectronic and thermoelectric devices.
Understanding Performance Limiting Interfacial Recombination in pin Perovskite Solar Cells
Authors: Warby Jonathan , Zu Fengshuo , Zeiske Stefan , Gutierrez‐Partida Emilio , Frohloff Lennart , Kahmann Simon , Frohna Kyle , Mosconi Edoardo , Radicchi Eros , Lang Felix , Shah Sahil , Peña‐Camargo Francisco , Hempel Hannes , Unold Thomas , Koch Norbert , Armin Ardalan , De Angelis Filippo , Stranks Samuel D. , Neher Dieter , Stolterfoht Martin 
Published: February 2022

AbstractPerovskite semiconductors are an attractive option to overcome the limitations of established silicon based photovoltaic (PV) technologies due to their exceptional opto‐electronic properties and their successful integration into multijunction cells. However, the performance of single‐ and multijunction cells is largely limited by significant nonradiative recombination at the perovskite/organic electron transport layer junctions. In this work, the cause of interfacial recombination at the perovskite/C60 interface is revealed via a combination of photoluminescence, photoelectron spectroscopy, and first‐principle numerical simulations. It is found that the most significant contribution to the total C60‐induced recombination loss occurs within the first monolayer of C60, rather than in the bulk of C60 or at the perovskite surface. The experiments show that the C60 molecules act as deep trap states when in direct contact with the perovskite. It is further demonstrated that by reducing the surface coverage of C60, the radiative efficiency of the bare perovskite layer can be retained. The findings of this work pave the way toward overcoming one of the most critical remaining performance losses in perovskite solar cells.
A Kinetic and Fluorogenic Enhancement Strategy for Labeling of Nucleic Acids
Authors: Loehr Morten O. , Luedtke Nathan W. 
Published: February 2022

AbstractChemical modification of nucleic acids in living cells can be sterically hindered by tight packing of bioorthogonal functional groups in chromatin. To address this limitation, we report here a dual enhancement strategy for nucleic acid‐templated reactions utilizing a fluorogenic intercalating agent capable of undergoing inverse electron‐demand Diels–Alder (IEDDA) reactions with DNA containing 5‐vinyl‐2′‐deoxyuridine (VdU) or RNA containing 5‐vinyl‐uridine (VU). Reversible high‐affinity intercalation of a novel acridine–tetrazine conjugate “PINK” (KD=5±1 μM) increases the reaction rate of tetrazine–alkene IEDDA on duplex DNA by 60 000‐fold (590 M−1 s−1) as compared to the non‐templated reaction. At the same time, loss of tetrazine–acridine fluorescence quenching renders the reaction highly fluorogenic and detectable under no‐wash conditions. This strategy enables live‐cell dynamic imaging of acridine‐modified nucleic acids in dividing cells.
Site‐Directed Chemical Modification of Amyloid by Polyoxometalates for Inhibition of Protein Misfolding and Aggregation
Authors: Gao Nan , Liu Zhenqi , Zhang Haochen , Liu Chun , Yu Dongqin , Ren Jinsong , Qu Xiaogang 
Published: February 2022

AbstractPost‐translational modification (PTM) of protein can significantly change protein conformation and function. Inspired by the natural PTM, we present a new approach to inhibit amyloid aggregation by chemical PTM modification. Polyoxometalates (POMs) were used as examples of inhibitors of β‐amyloid peptide (Aβ) aggregation to illustrate the chemical PTM method. After the POMs were modified with thiazolidinethione (TZ), the resulting POMD‐TZ acted as a chemical PTM agent and could covalently modify Aβ site‐selectively at Lys16. Multiple biophysical techniques and biochemical assays have been employed to show the superiority of the chemical PTM method compared to traditional Aβ inhibitors. Since Aβ oligomers are more cytotoxic, we further functionalized POMD‐TZ with an Aβ‐targeted peptide and a fluorescent probe to obtain an “Aβ oligomer sensitive” probe. The use of PTM agents for the site‐directed chemical modification of proteins provides a new way to regulate amyloid aggregation.
Accelerating the Crystallization of Zeolite SSZ‐13 with Polyamines
Authors: Dai Heng , Claret Jakob , Kunkes Eduard L , Vattipalli Vivek , Linares Noemi , Huang Chenfeng , Fiji Muhammad , García‐Martinez Javier , Moini Ahmad , Rimer Jeffrey D. 
Published: February 2022

AbstractTailoring processes of nucleation and growth to achieve desired material properties is a pervasive challenge in synthetic crystallization. In systems where crystals form via nonclassical pathways, engineering materials often requires the controlled assembly and structural evolution of colloidal precursors. In this study, we examine zeolite SSZ‐13 crystallization and show that several polyquaternary amines function as efficient accelerants of nucleation, and, in selected cases, tune crystal size by orders of magnitude. Among the additives tested, polydiallyldimethylammonium (PDDA) was found to have the most pronounced impact on the kinetics of SSZ‐13 formation, leading to a 4‐fold reduction in crystallization time. Our findings also reveal that enhanced nucleation occurs at an optimal PDDA concentration where a combination of light‐scattering techniques demonstrate these conditions lead to polymer‐induced aggregation of amorphous precursors and the promotion of (alumino)silicate precipitation from the growth solution. Here, we show that relatively low concentrations of polymer additives can be used in unique ways to dramatically enhance SSZ‐13 crystallization rates, thereby improving the overall efficiency of zeolite synthesis.
A design method for half‐pipe jacketed vessels based on numerical limit‐load analysis
Authors: Li Weicong , Li Huifang , Shi Hong , Qian Caifu 
Published: February 2022

AbstractAs one kind of jacketed vessels, half‐pipe jacketed vessels are widely used in engineering owing to the structural and heat transfer advantages. But for the design of half‐pipe jacketed vessels, there are limitations in codes ASME VIII‐1 and ASME VIII‐2. In this paper, a new design method based on numerical limit‐load analysis is proposed to design half‐pipe jacketed vessels. The scheme and advantages of the method are presented through a design of half‐pipe jacketed vessel. It is found that by performing limit‐load analysis, problems of the codes ASME VIII‐1 and ASME VIII‐2 about the structural limitation of the half‐pipe jacketed vessels and loading limitation are solved. In addition, by performing limit‐load and parametric analysis, the strength weakness areas on the vessels can be found, and the rational strength design of a structure can be achieved.
First reported case of delayed‐type hypersensitivity reaction to non‐hyaluronic acid Polycaprolactone dermal filler following COVID‐19 vaccination: A case report and a review of the literature
Authors: Kalantari Yasamin , Sadeghzadeh‐Bazargan Afsaneh , Aryanian Zeinab , Hatami Parvaneh , Goodarzi Azadeh 
Published: February 2022

AbstractCases of filler reactions after COVID‐19 vaccination have been reported. Here, we present the first case of delayed‐type reaction (DTR) to non‐hyaluronic acid Polycaprolactone dermal filler after the second dose of Sinopharm COVID‐19 vaccine which was improved with administration of topical and intralesional steroids.
Natural pollen exposure increases in a dose‐dependent way Fraction of exhaled Nitric Oxide (FeNO) levels in patients sensitized to one or more pollen species
Authors: Olivieri Mario , Marchetti Pierpaolo , Murgia Nicola , Nicolis Morena , Torroni Lorena , Spiteri Gianluca , Ferrari Marcello , Marcon Alessandro , Verlato Giuseppe 
Published: February 2022

AbstractBackgroundCo‐exposures and polysensitization to several pollen species are very common in real life practice. However, little information exists on allergic symptoms and airway inflammation related to natural pollen exposure in large general population samples.ObjectiveTo assess the combined effect of sensitization and/or exposure to one or more pollen species on Fraction of exhaled Nitric Oxide (FeNO) levels.MethodsWithin Gene Environment Interactions in Respiratory Diseases (GEIRD) multicase‐control study, 1070 adults from the general population of Verona, Italy, underwent a clinical evaluation including standardized interview, spirometry, skin prick test to inhalants and FeNO measurement. Pollen exposure was assumed, when the mean pollen concentration in the previous week was above the cutoff established by the Italian Aerobiological Monitoring Network.ResultsSubjects sensitized to one or more pollen species were respectively 15.5% and 29.6%. FeNO levels were directly related to the number of both pollen species around and pollen‐related sensitizations. Median FeNO levels were directly related to number of pollen species around and pollen sensitization. FeNO levels increased from 15.4 ppb (p. 25–p. 75 = 9.9–21.0) outside the pollen season to 17.5 ppb (11.2–30.5) when there were ≥3 pollen species around. Likewise FeNO levels rose from 14.8 ppb (10.0–22.3) in not sensitized subjects, to 16.7 (10.1–25.0) in monosensitized and further to 20.4 (12.3–40.6) in poly‐sensitized. According to multivariable quantile regression, median FeNO was 17.9 ppb higher (p. 25–p. 75 = 12.5–23.3) for subjects sensitized and exposed to more than one pollen species, compared to subjects who were neither sensitized nor exposed. Differences in FEV1/FVC between groups were less pronounced (−2.0%, −4.1 to 0.1). Median FeNO level was 15.1 ppb (p. 25–p. 75 = 10.0–23.2) in subjects without pollen‐related symptoms, 17.8 ppb (12.1–40.2) in those with nasal symptoms only, and 22.7 ppb (14.7–43.0) in those with asthma‐like symptoms (p < 0.001).Conclusion and clinical relevanceAirways inflammation, evaluated by FeNO, increases in dose‐dependent manner from subjects monosensitized to pollen species to those poly‐sensitized, especially when asthma‐like symptoms on pollen exposure are also reported. This should be considered by allergists during natural pollen seasons when evaluating both pulmonary function and airways inflammation.
Regard and protect ground‐nesting pollinators as part of soil biodiversity
Authors: Christmann Stefanie 
Published: February 2022

AbstractWhile the Convention on Biological Diversity employs a habitat‐oriented definition of soil biodiversity including all kinds of species living in soil, the Food and Agriculture Organization, since 2002 assigned to safeguard soil biodiversity, excludes them by focusing on species directly providing four ecosystem services contributing to soil quality and functions: nutrient cycling, regulation of water flow and storage, soil structure maintenance and erosion control, and carbon storage and regulation of atmospheric composition. Many solitary wasps and 70% of wild bees nest below ground and require protection during this long and crucial period of their lifecycle. Recent research has demonstrated the extent of threats to which ground‐nesting pollinators are exposed, for example, chemicals and deep tillage. Ground‐nesting pollinators change soil texture directly by digging cavities, but more importantly by their indirect contribution to soil quality and functions: 87% of all flowering plants require pollinators. Without pollinators, soil would lose all ecosystem services provided by these flowering plants, for example, litter, shade, roots for habitats, and erosion control. Above‐ and belowground biota are in constant interaction. Therefore, and in line with the Convention's definition, the key stakeholder, the Food and Agriculture Organization should protect ground‐nesting pollinators explicitly within soil biodiversity conservation.
Plant effects on and response to soil microbes in native and non‐nativePhragmites australis
Authors: Bickford Wesley A. , Goldberg Deborah E. , Zak Donald R. , Snow Danielle S. , Kowalski Kurt P. 
Published: February 2022

AbstractPlant–soil feedbacks (PSFs) mediate plant community dynamics and may plausibly facilitate plant invasions. Microbially mediated PSFs are defined by plant effects on soil microbes and subsequent changes in plant performance (responses), both positive and negative. For microbial interactions to benefit invasive plants disproportionately, native and invasive plants must either (1) have different effects on and responses to soil microbial communities or (2) only respond differently to similar microbial communities. In other words, invasive plants do not need to cultivate different microbial communities than natives if they respond differently to them. However, effects and responses are not often explored separately, making it difficult to determine the underlying causes of performance differences. We performed a reciprocal‐transplant PSF experiment with multiple microbial inhibition treatments to determine how native and non‐native lineages ofPhragmites australisaffect and respond to soil bacteria, fungi, and oomycetes. Non‐nativePhragmitesis a large, fast‐growing, cosmopolitan invasive plant, whereas the North American native variety is comparatively smaller, slower growing, and typically considered a desirable wetland plant. We identified the effects of each plant lineage on soil microbes using DNA meta‐barcoding and linked plant responses to microbial communities. BothPhragmiteslineages displayed equally weak, insignificant PSFs. We found evidence of slight differential effects on microbial community composition, but no significant differential plant responses. Soils conditioned by each lineage differed only slightly in bacterial community composition, but not in fungal composition. Additionally, native and non‐nativePhragmiteslineages did not significantly differ in their response to similar soil microbial communities. Neither lineage appreciably differed when plant biomass was compared between those grown in sterile and live soils. Targeted microbial inhibitor treatments revealed both lineages were negatively impacted by soil bacteria, but the negative response was stronger in non‐nativePhragmites. These observations were opposite of expectations from invasion theory and imply that the success of non‐nativePhragmites, relative to the native lineage, does not result from its interaction with soil microorganisms. More broadly, quantifying plant effects on, and responses to soil microbes separately provides detailed and nuanced insight into plant‐microbial interactions and their role in invasions, which could inform management outcomes for invasive plants.
Niche partitioning in a guild of invasive mammalian predators
Authors: Garvey Patrick M. , Glen Alistair S. , Clout Mick N. , Nichols Margaret , Pech Roger P. 
Published: February 2022

AbstractPredators compete aggressively for resources, establishing trophic hierarchies that influence ecosystem structure. Competitive interactions are particularly important in invaded ecosystems where introduced predators can suppress native prey species. We investigated whether niche partitioning exists within a guild of invasive mammalian predators and determined the consequences for native species. Over 4405 camera‐trap days, we assessed interactions among three invasive predators: two apex predators (feral catsFelis catusand ferretsMustela furo) and a mesopredator (stoatsMustela erminea), in relation to their primary prey (lagomorphs, rodents and birds) and habitat use. Further, we tested for mesopredator release by selectively removing cats and ferrets in a pulse perturbation experiment. We found compelling evidence of niche partitioning; spatiotemporal activity of apex predators maximized access to abundant invasive prey, with ferrets targeting lagomorphs and cats targeting rodents. Mesopredators adjusted their behavior to reduce the risk of interference competition, thereby restricting access to abundant prey but increasing predation pressure on diurnal native birds. Stoats were only recorded at the treatment site after both larger predators were removed, becoming the most frequently detected predator at 6 months post‐perturbation. We suggest there is spatial and resource partitioning within the invasive predator guild, but that this is incomplete, and avoidance is achieved by temporal partitioning within overlapping areas. Niche partitioning among invasive predators facilitates coexistence, but simultaneously intensifies predation pressure on vulnerable native species.
Potential impacts of emerald ash borer and adaptation strategies on wildlife communities in black ash wetlands
Authors: R. Grinde Alexis , B. Youngquist Melissa , A. Slesak Robert , R. Kolbe Stephen , D. Bednar Josh , J. Palik Brian , W. D'Amato Anthony 
Published: February 2022

AbstractBlack ash wetlands cover approximately 1.2 million ha of wetland forest in the western Great Lakes region, providing critical habitat for wildlife. The future of these wetlands is critically threatened by a variety of factors, including emerald ash borer (Agrilus planipennis; emerald ash borer [EAB]), which has been eliminating native populations of otherwise healthy ash throughout the Great Lakes region since it was discovered in 2002. To quantify the potential impacts of tree mortality from EAB on wildlife communities, we measured seasonal bird, mammal, and amphibian diversity in black ash wetlands using a dual approach: (1) documenting bird and amphibian species across 27 mature reference black ash wetlands in northern Minnesota, USA and (2) assessing how bird, mammal, and amphibian communities respond to experimental manipulations of black ash forests that emulate mortality and management strategies related to the potential impact of EAB. In total, 85 wildlife species were recorded for the entire study including 57 bird species, 5 amphibian species, and 23 mammal species. Results from the reference sites show that hydrologic regime, percentage of ash canopy cover, and understory cover were important habitat characteristics for bird and amphibian communities. Results from the experimental sites show there may be short‐term increases in species richness for mammal and bird communities associated with changes in forest structure due to ash mortality; however, anticipated changes resulting from EAB‐caused mortality, particularly the conversion of these sites to non‐forested wetlands, will lead to significant shifts in bird and mammal community composition. Loss of ash may cause declines in forest‐dependent species and increases in open‐canopy and wetland‐associated species. Additionally, whereas increased ponding extent and longer hydroperiods may be beneficial for some amphibian species, the loss of the forest canopy will result in an overall decrease in bird diversity and reduce forest connectivity for all species. Our results indicate the potential for significant large‐scale impacts of black ash mortality on forest‐associated wildlife. Management strategies that focus on establishing alternative trees species to maintain long‐term forest cover and structural complexity in these wetlands will help to maintain and conserve wildlife diversity.