bluuebunny/crossref_metadata_2025_split huggingface dataset:
„Schenkelhalsklingen-Cut-in“ nach Osteosynthese einer pertrochantären Femurfraktur mittels TFNA©
Authors: Reimond Mathias , Gross Thomas 
Published: April 2022

ZusammenfassungEin 96-jähriger Patient erlitt nach der TFNA©-Osteosynthese einer pertrochantären Femurfraktur trotz korrekter Reposition und Fixation einen vollständigen „cut-in“, d. h. eine Medialisierung der gesamten Schenkelhalsklinge im Nagel ins Hüftgelenk. Vor dem Hintergrund der Implantatentwicklung und anhand der aktuellen Literatur wird diese häufiger werdende Komplikationsart beschrieben bzw. vom Fixationsversagen des „cut-out“ unterschieden. Bisherige Erklärungsversuche und notwendige Forschungsansätze werden aufgezeigt und abschließend ein pragmatisches Vorgehen im Alltag dargelegt.
The dark side of social capital: a contextual perspective
Authors: Baycan Tüzin , Öner Özge 
Published: April 2022

AbstractThis paper aims to provide a brief review of the much neglected ‘dark side’ of social capital. To highlight the contextual nature of social capital by way of examples from different geographies, we draw attention to the potentially detrimental effects associated with the concept. A significant body of literature addresses the advantages of being connected to various types of social bridges and bonds. While emphasising the ‘bright side’ of social capital, that literature pays limited attention to the negative attributes of social ties and their potentially detrimental effects on a number of social and economic outcomes. Although it is not reasonable to establish a dichotomy between ‘good’ and ‘bad’ social capital, it is possible to conceptualise such negative attributes in the light of the existing literature, in which the context-dependent nature of social capital is accentuated. We focus on two critical questions: (i) Why is it essential to address the contextual nature of social capital? (ii) How could geography come into play?
The use of non-financial performance measures for managerial compensation: evidence from SMEs
Authors: Alves Iryna , Lourenço Sofia M. 
Published: April 2022

AbstractThis study explores the relationship between contextual variables—strategy, perceived environmental uncertainty (PEU), and decentralization—and the use of non-financial performance measures (NFPM) for managerial compensation in small and medium enterprises (SMEs). Using questionnaire data from SMEs’ managers, we find that the use of NFPM is positively associated with PEU hostility and decentralization. Furthermore, our study shows that these results are mostly driven by CEO’s compensation (in comparison to non-CEOs compensation) and family firms (in comparison to non-family firms). Finally, our analyses reveal that the use of different types of NFPM (customer-oriented, employee-oriented and operations-oriented) is associated with distinct contextual variables. Particularly, customer-oriented NFPM are negatively related to PEU dynamism and positively related to decentralization, while operations-oriented NFPM are positively related to PEU hostility.
Adhesion and aggregation properties of Lactobacillaceae strains as protection ways against enteropathogenic bacteria
Authors: Zawistowska-Rojek Anna , Kośmider Anita , Stępień Karolina , Tyski Stefan 
Published: April 2022

AbstractThe adhesion and aggregation are characteristic attributes of probiotic strains belonging to Lactobacillaceae genus. Due to these properties the host organisms can avoid colonisation of the intestinal tract by enteropathogenic bacteria. The presented research includes a comparison of the properties of various strains belonging to different Lactobacillaceae species and isolated from different sources The aim of this study was to investigate the ability of Lactocaseibacillus rhamnosus, Lactiplantibacillus plantarum, and Lactobacillus strains (L. acidophilus, L. gasseri, L. ultunensis) from probiotic products and clinical specimens to direct and competitive adherence to Caco-2 and HT-29 cell lines. Furthermore, the ability of lactobacilli and enteropathogenic bacteria, E. coli, E. faecalis, and S. Typhimurium, to auto- and co-aggregation was also investigated.The results showed that all tested strains adhered to Caco-2 and HT-29 cell lines. Though, the factor of adhesion depended on the species and origin of the strain. L. rhamnosus strains showed a lowest degree of adherence as compared to L. plantarum and Lactobacillus sp. strains. On the other side both, L. rhamnosus and L. acidophilus strains reduced the pathogenic bacteria in competition adherence test most effectively. All tested lactobacilli strains were characterised by auto- and co-aggregation abilities, to various degrees. The properties of Lactobacillaceae strains analysed in this study, like adhesion abilities, competitive adherence, auto- and co-aggregation, may affect the prevention of colonisation and elimination of pathogenic bacteria in gastrointestinal tract.
On Globalized Traces for the Poisson Sigma Model
Authors: Moshayedi Nima 
Published: April 2022

AbstractA globalized version of a trace formula for the Poisson Sigma Model on the disk is presented by using its formal global picture in the setting of the Batalin–Vilkovisky formalism. This global construction includes the concept of zero modes. Moreover, for the symplectic case of the Poisson Sigma Model with cotangent target, the globalized trace reduces to a symplectic construction which was presented by Grady, Li and Li for 1-dimensional Chern–Simons theory (topological quantum mechanics). In addition, the connection between this formula and the Nest–Tsygan theorem and the Tamarkin–Tsygan theorem is explained.
Prevalence and patient-rated relevance of complexity factors in medication regimens of community-dwelling patients with polypharmacy
Authors: Wurmbach Viktoria S. , Schmidt Steffen J. , Lampert Anette , Bernard Simone , Meid Andreas D. , Frick Eduard , Metzner Michael , Wilm Stefan , Mortsiefer Achim , Bücker Bettina , Altiner Attila , Sparenberg Lisa , Szecsenyi Joachim , Peters-Klimm Frank , Kaufmann-Kolle Petra , Thürmann Petra A. , Haefeli Walter E. , Seidling Hanna M. 
Published: April 2022

Abstract
Purpose
To describe the prevalence of complexity factors in the medication regimens of community-dwelling patients with more than five drugs and to evaluate the relevance of these factors for individual patients.

Methods
Data were derived from the HIOPP-6 trial, a controlled study conducted in 9 general practices which evaluated an electronic tool to detect and reduce complexity of drug treatment. The prevalence of complexity factors was based on the results of the automated analysis of 139 patients’ medication data. The relevance assessment was based on the patients’ rating of each factor in an interview (48 patients included for analysis).

Results
A median of 5 (range 0–21) complexity factors per medication regimen were detected and at least one factor was observed in 131 of 139 patients. Almost half of these patients found no complexity factor in their medication regimen relevant.

Conclusion
In most medication regimens, complexity factors could be identified automatically, yet less than 15% of factors were indeed relevant for patients as judged by themselves. When assessing complexity of medication regimens, one should especially consider factors that are both particularly frequent and often challenging for patients, such as use of inhalers or tablet splitting.

Trial registration
The HIOPP-6 trial was registered retrospectively on May 17, 2021, in the German Clinical Trials register under DRKS-ID DRKS00025257.
The Use of a Commercially Available Endovascular Filter Catheter (Capturex®) for Thoracic Endovascular Aortic Repair (TEVAR) in a Patient with a Coral Reef Aorta
Authors: Portugaller Rupert Horst , Steiner Jakob , Schmid Florian , Knez Igor , Asslaber Martin , Deutschmann Hannes A. 
Published: April 2022

AbstractDue to the risk of mobilizing plaque fragments, transfemoral TEVAR is a potentially dangerous procedure in patients with a coral reef aorta. We describe a practical method for transfemoral TEVAR in a patient with a degenerative thoracic aneurysm and a coral reef aorta. After placing a filter catheter in the abdominal aorta via a contralateral percutaneous femoral access, a working channel through the distal thoracic aorta was created with a balloon-expandable stent graft in the coral reef segment. Thereafter, transfemoral TEVAR could be performed successfully, without any complications. The additional use of a percutaneously placed filter catheter potentially allows reduction of peripheral embolism and hence may prevent patients from more invasive treatment.
The structure of near-wall re-entrant flow and its influence on cloud cavitation instability
Authors: Gawandalkar Udhav , Poelma Christian 
Published: April 2022

AbstractThe so-called ‘re-entrant jet’ is fundamental to periodic cloud shedding in partial cavitation. However, the exact physical mechanism governing this phenomenon remains ambiguous. The complicated topology of the re-entrant flow renders whole-field, detailed measurement of the re-entrant flow cumbersome. Hence, most studies in the past have derived a physical understanding of this phenomenon from qualitative analyses of the re-entrant jet. Thus, quantitative studies are scarce in the literature. In this work, we present a methodology to experimentally measure the re-entrant flow below the vapour cavity in an axisymmetric venturi. The axisymmetry of the flow geometry is exploited to image tracer particles in the near-wall re-entrant flow. The main objective of employing tomographic imaging and subsequent velocimetry is to resolve the thickness and the velocity of the re-entrant flow. Additionally, phase-averaging conditioned on cavity length sheds light on the temporal evolution of re-entrant flow in a shedding cycle. The measured re-entrant film is as thick as$$\sim 1.2$$∼1.2mm for a maximum cavity length of$$\sim 0.9 D_{t}$$∼0.9Dt, where$$D_{t}$$Dtis the venturi throat diameter. However, the re-entrant film thickness at higher cavitation number is measured to be about 0.5 mm. Further, the re-entrant flow is seen to attain a maximum velocity up to half the throat velocity as the vapour cavity grows in time and the re-entrant flow thickens. We observe that a complex spatio-temporal evolution of re-entrant flow is involved in the cavity detachment and periodic cloud shedding. Finally, we apply the demonstrated methodology to study the evolution of the near-wall liquid flow, below the vapour cavity in different cavity shedding flow regimes. The role of two main mechanisms responsible for cloud shedding, i.e. (i) the adverse-pressure gradient driven re-entrant jet, and (ii) the bubbly shock wave emanating from the cloud collapse are quantitatively assessed. We observe that the thickness of the re-entrant liquid film with respect to the cavity thickness can influence the cavity shedding behaviour. Further, we show that both the mechanisms could be operating at a given flow condition, with one of them dominating to dictate the cloud shedding behaviour.Graphical abstract
Atmospheric trends over the Arctic Ocean in simulations from the Coordinated Regional Downscaling Experiment (CORDEX) and their driving GCMs
Authors: Reader Mary Catherine , Steiner Nadja 
Published: April 2022

AbstractThe Arctic Coordinated Regional Downscaling Experiment (Arctic-CORDEX) uses regional climate models (RCMs) to downscale selected Fifth Coupled Model Intercomparison Project simulations, allowing trend validation and projection on subregional scales. For 1986–2015, the CORDEX seasonal-average near-surface temperature (tas), wind speed (sfcWind), precipitation (pr) and snowfall (prsn) trends are generally consistent with analyses/observations for the Arctic Ocean regions considered. The projected Representative Concentration Pathway 8.5 (RCP8.5) 2016–2100 subregional annual tas trends range from 0.03 to 0.18 K/year. Projected annual pr and prsn trends have a large inter-model spread centered around approximately 5.0 × 10–8 mm/s/year and −5.0 × 10–8 mm/s/year, respectively, while projected sfcWind summer and winter trends range between 0.0 and 0.4 m/s/year. For all variables except prsn, and sometimes total precipitation, the driving general circulation model (GCM) dominates the trends, however there is a tendency for the GCMs to underestimate the sfcWind trends compared to the RCMs. Subtracting the Arctic-Ocean mean from subregional trends reveals a consistent, qualitative anomaly pattern in several variables and seasons characterized by greater-than or average trends in the central and Siberian Arctic Ocean and lesser or average trends in the Atlantic Sector and the Bering Sea, related to summer sea-ice trends. In particular, a strong proportional relationship exists between the summer sea-ice concentration and fall tas and sfcWind trend anomalies. The RCP4.5 annual, multi-model mean trends are 35–55% of the corresponding RCP8.5 trends for most variables and subregions.
Periprocedural myocardial injury according to optical characteristics of neointima and treatment modality of in-stent restenosis
Authors: Nano Nejva , Aytekin Alp , Ndrepepa Gjin , Seguchi Masaru , Bresha Jola , Alvarez Covarrubias Hector Alfonso , Nicol Philipp , Lenz Tobias , Lahu Shqipdona , Gewalt Senta , Voll Felix , Rheude Tobias , Wiebe Jens , Schunkert Heribert , Kufner Sebastian , Cassese Salvatore , Joner Michael , Kastrati Adnan , Xhepa Erion 
Published: April 2022

Abstract
Aims
Aim of the present study was to investigate the impact of increasing neointimal inhomogeneity and neoatherosclerosis as well as of treatment modality of in-stent restenosis (ISR) on the occurrence of periprocedural myocardial injury (PMI).

Methods and results
Patients with normal or stable/falling increased baseline high-sensitivity troponin T (hs-cTnT) undergoing intravascular optical coherence tomography (OCT) and subsequent percutaneous coronary intervention (PCI) of ISR by means of drug-coated balloon (DCB) or drug-eluting stent (DES) were included. Overall, 128 patients were subdivided into low (n = 64) and high (n = 64) inhomogeneity groups, based on the median of distribution of non-homogeneous quadrants. No significant between-group differences were detected in terms of hs-cTnT changes (28.0 [12.0–65.8] vs. 25.5 [9.8–65.0] ng/L; p = 0.355), or the incidence of major PMI (31.2 vs. 31.2%; p = 1.000). Similarly, no differences were observed between DCB- and DES-treated groups in terms of hs-cTn changes (27.0 [10.0–64.0] vs. 28.0 [11.0–73.0] ng/L; p = 0.795), or the incidence of major PMI (28.9 vs. 35.6%; p = 0.566). Additionally, no significant interaction was present between optical neointimal characteristics and treatment modality in terms of changes in hs-cTnT (Pint = 0.432). No significant differences in PMI occurrence were observed between low and high neoatherosclerosis subgroups.

Conclusions
In patients undergoing PCI for ISR, there was no association between increasing neointimal inhomogeneity, or increasing expression of neoatherosclerotic changes and occurrence of PMI. PMI occurrence was not influenced by the treatment modality (DCB vs. DES) of ISR lesions, a finding that supports the safety of DCB treatment for ISR.

Graphical abstract
Recognized and unrecognized dural punctures in 12,981 labor epidurals: an audit of management
Authors: Eley Victoria A. , Abeypala Wally , Kelley Andrea , Kumta Nihal , Chin Adrian 
Published: April 2022

Abstract
Purpose
Unintentional dural puncture (DP) and post-dural puncture headache (PDPH) continue to cause discomfort and disability in a small proportion of post-partum women. We report an audit of the management of recognized and unrecognized DP over 10 years.

Methods
Clinical data were prospectively collected for women who experienced a recognized DP or developed symptoms following a neuraxial procedure. Details were documented regarding patient characteristics, the neuraxial procedure, symptoms reported, and epidural blood patches. We reported rates of recognized DP, unrecognized DP, PDPH, and blood patches performed. Data were presented as number (percent) and proportions of interest compared using Chi square analysis.

Results
Between January 2009 and December 2018, 12,981 women utilized labor epidural analgesia. A recognized DP occurred in 131 (1.0%) and an unrecognized DP in 60 (0.5%), with unrecognized DPs comprising 31% of the total. Of 131 recognized punctures, 86 (66%) developed a PDPH. A total of 146 (1.1%) women experienced a PDPH. Of those, a blood patch was performed in 93 (64%). Intrathecal catheters were inserted for > 24 h in 43 (33%) women with a recognized DP. Of those, 33 (77%) developed a PDPH, compared to 53 (60%) of those without an intrathecal catheter in situ for > 24 h (P = 0.06).

Conclusions
Rates of DP were consistent with those reported by others. Unrecognized DP comprised a third of all DP, and systematic post-neuraxial follow-up is essential to identify these women. Epidural blood patch was performed in most women experiencing symptoms of PDPH.
Open-aqueduct LOVA, LIAS, iNPH: a comparative clinical-radiological study exploring the “grey zone” between different forms of chronic adulthood hydrocephalus
Authors: Palandri Giorgio , Carretta Alessandro , La Corte Emanuele , Giannini Giulia , Martinoni Matteo , Mantovani Paolo , Albini-Riccioli Luca , Tonon Caterina , Mazzatenta Diego , Elder Benjamin D. , Conti Alfredo 
Published: April 2022

Abstract
Purpose
The definition of chronic adult hydrocephalus encompasses different pathological entities with overlapping characteristics, including long-standing overt ventriculomegaly in adults (LOVA), late-onset idiopathic aqueductal stenosis (LIAS) and idiopathic normal pressure hydrocephalus (iNPH). The aim of our study was to identify preoperative clinical and radiological features peculiar of these diseases providing some pathophysiology inferences on these forms of hydrocephalus.

Methods
Clinical and radiological preoperative records, type of surgical treatment and clinical outcome of patients with chronic adult hydrocephalus who were surgically treated between 2013 and 2019 were retrospectively reviewed. Univariate and multivariate analyses were performed to evaluate the contribution of each variable to the differential diagnosis.

Results
In total, 105 patients were included: 18 with LOVA, 23 with LIAS and 64 with iNPH. On multivariate analysis, an enlarged cisterna magna and a more severe ventriculomegaly were associated with the diagnosis of LOVA, while an older age and DESH with iNPH. LIAS patients tend to have an higher prevalence of raised ICP symptoms. Based on that, a clinical and radiological scoring system was developed to distinguish between iNPH and no iNPH cases. A precise cut-off value with a sensitivity of 95.1% and a specificity of 90.6% was identified.

Conclusions
LOVA, LIAS and iNPH are different forms of chronic adulthood hydrocephalus and present different and peculiar clinical and radiological features, with an impact on the treatment and outcome prediction. The implementation of a clinical-radiological score for differential diagnosis may help the differentiation. Further studies are warranted.
The clinical impact of direct-acting antiviral treatment on patients affected by hepatitis C virus-related oral lichen planus: a cohort study
Authors: Di Stasio Dario , Lucchese Alberta , Romano Antonio , Adinolfi Luigi Elio , Serpico Rosario , Marrone Aldo 
Published: April 2022

Abstract
Objectives
Oral lichen planus (OLP) is a chronic inflammatory mucocutaneous disease. Literature supports an association between OLP and Hepatitis C virus (HCV) infection. The current treatment for HCV infection with direct-acting antivirals (DAAs) is highly effective and safe. The aim of this study is to evaluate the clinical impact of viral eradication with DAAs in patients with HCV and OLP.

Materials and methods
For this cohort observational study, 18 patients with HCV and OLP were recruited; all patients received DAAs. Nineteen patients with OLP without HCV were recruited as controls. Both groups received an oral clinical examination, taking photographs of the oral mucosa, at three time points. Size and type of lesions, clinical and efficacy scores, were evaluated at each time point with ImageJ software. Changes were assessed by a general linear model repeated measures analysis. Kruskal–Wallis H and Mann–Whitney U tests were used to evaluate the differences between subgroups.

Results
All patients of the study group reached a sustained virological response. The study group showed a correlation between viral load and clinical status (p < 0.05), higher clinical scores at baseline (p = 0.001) and higher efficacy index than controls (p < 0.001), improving over time (p < 0.001); controls did not show significant changes (p = 0.196). One patient of the experimental group developed oral squamous cell carcinoma (OSCC) of the tongue during the DAAs treatment.

Conclusions
In this study, patients with HCV and OLP showed a worst clinical oral status than controls at baseline. However, treatment for virus eradication can improve the oral lichen planus clinical course.

Clinical relevance
HCV eradication can improve the clinical course of patients with HCV-related OLP.
Effect of different binders and secondary carbides on NbC cermets
Authors: Hübler Daniela , Gradt Thomas 
Published: April 2022

AbstractDue to the rapidly increasing price of tungsten carbide and the significant health risks associated with the wear products of WC-Co (Co3O4 and Wo3), an alternative is required. Niobium carbide (NbC) is well suited as a cutting tool due to its high melting point and low solubility in iron. Compared to pure NbC, a complete substitution of WC to NbC-Co resulted in an increased toughness and strength. As alternative binders, nickel and iron-based binders were subsequently investigated. Although iron-based cermets would be an economical, low-cost alternative to NbC-Ni cermets, they showed a higher coefficient of friction and wear rate. So far, NbC-Ni cermets best met the requirements of high hardness and toughness. Various secondary carbides such as VC, Mo2C, TiC, but also WC were added to further improve the hardness. Elemental analyses of NbC-Ni-MeC cermets (Me = metal) showed that the binder is a face-centered cubic solid solution, while the NbC phase is a solid solution of the type (Nb, Me)C.