bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Dual‐Phase Electrolyte for High‐Energy Lithium–Sulfur Batteries
Authors: Ren Yuxun , Manthiram Arumugam 
Published: October 2022

AbstractDissolution of lithium polysulfides (LiPSs) is essential for fast cathode kinetics, but detrimental for anode stability, especially under lean electrolyte conditions. In this work, the phase separation phenomenon between solvents with different polarities (tetramethyl sulfone [TMS] and dibutyl ether [DBE]) is utilized to enable the design of a dual‐phase electrolyte. High‐polarity, high‐density TMS–lithium bis(trifluoromethanesulfonyl)imide–ammonium trifluoroacetate as the cathode electrolyte strongly solvates LiPSs, which propel the sulfur redox reaction. Moreover, the composite of DBE and a polymeric ion conductor serves as the anode electrolyte. The addition of DBE in the anode side effectively prevents the crossover of corrosive species (LiPSs and ammonia trifluoroacetate), enabling a significant improvement in Li‐metal anode stability. The electrode‐specific dual‐phase electrolyte design provides electrochemical performance superior to conventional electrolytes. Without additional electrode engineering, pouch cells assemble with the dual‐phase electrolyte cycle under a lean electrolyte (4 µL mg−1) and low‐Li‐excess condition (N/P = 3) for 120 cycles.
Effect of irrigation regimes and planting patterns on maize production in humid climates
Authors: Pinnamaneni Srinivasa R. , Anapalli Saseendran S. , Reddy Krishna 
Published: October 2022

AbstractTwin‐row planting in maize (Zea mays L.) has potential for reducing plant‐crowding stress for optimizing grain yield and resource use. A study was conducted in 2020 and 2021 on a Dundee silt loam in the Lower Mississippi Delta (LMD) region of the United States to evaluate maize grain yield and irrigation water use efficiency (IWUE) in single‐row (SR) and twin‐row (TR) planting patterns with same seed rate under four irrigation regimes: rainfed (RF), all‐furrow irrigation (FI), alternate‐furrow irrigation (AFI), and every third‐furrow irrigation (TFI). The TR enhanced grain yield by 9.2% in 2020 and 10.9% in 2021 over the SR system. The average final plant density at the reproductive phase was highest under AFI (73,900 ha−1) and lowest under RF (70,480 ha−1). Across all irrigation regimes, the leaf area index was significantly higher in the TR system. Average grain yields under SR were 10.01, 10.44, 9.48 and 9.10 Mg ha−1, respectively, in FI, AFI, TFI and RF; average grain yields under TR were 11.58, 11.32, 10.13 and 9.91 Mg ha−1. The AFI and FI recorded similar grain yields. The IWUE was highest in TR planting (0.028 kg m−3), followed by SR planting (0.024 kg m−3) under AFI. The IWUE of TFI in TR planting was 0.020 kg m−3 and in SR was 0.011 kg m−3. Economic analysis revealed that the TR‐FI and TR‐AFI had average profits of 446 and 432 US$ ha−1, respectively. The study suggests that maize producers in the LMD can save a significant amount of irrigation water without compromising grain yields by adapting the AFI‐TR system.
Primary tracheobronchial necrosis after esophagectomy: A nationwide multicenter retrospective study in Japan
Authors: Sakai Makoto , Saeki Hiroshi , Sohda Makoto , Korematsu Mizuki , Miyata Hiroshi , Murakami Daizo , Baba Yoshifumi , Ishii Ryo , Okamoto Hiroshi , Shibata Tomotaka , Shirabe Ken , Toh Yasushi , Shiotani Akihiro ,   The Japan Broncho‐Esophagological Society
Published: October 2022

AbstractBackgroundThe clinical features of postoperative primary tracheobronchial necrosis (P‐TBN; the necrosis without anastomotic leakage or other cervical and mediastinal abscess) remains unclear. This nationwide multicenter retrospective study first investigated the clinical features of P‐TBN after esophagectomy for upper aerodigestive tract cancer with a large cohort.MethodsAs a study of the Japan Broncho‐Esophagological Society, a nationwide questionnaire survey was conducted in 67 institutions. The clinical data of 6370 patients who underwent esophagectomy for laryngeal, pharyngeal, and esophageal cancer between 2010 and 2019 were collected. Grades of P‐TBN were defined as follows: Grade 1, mucosal necrosis; Grade 2, transmural bronchial wall necrosis without fistula or perforation; Grade 3, transmural bronchial wall necrosis with fistula or perforation.ResultsP‐TBN was observed in 48 (0.75%) of 6370 patients. The incidences of P‐TBN for pharyngo‐laryngo‐cervical esophagectomy (PLCE; n = 1650), total pharyngo‐laryngo‐esophagectomy (TPLE; n = 205), and subtotal esophagectomy (SE; n = 4515) were 2.0%, 5.4%, and 0.1%, respectively. The upper mediastinal LN dissection (P = 0.016) and the higher level of the tracheal resection (P = 0.039) were significantly associated with a higher grade of necrosis in PLCE and TPLE. Overall survival rates were significantly lower in patients with Grade 2 (P = 0.009) and Grade 3 (P = 0.004) than in those with Grade 1.ConclusionThe incidence of TBN restricted to P‐TBN was lower than previously reported. Maintaining the tracheal blood flow is essential to prevent worsening P‐TBN, especially in PLCE and TPLE. Our new P‐TBN severity grade may predict the outcome of patients with P‐TBN.
Vibration‐Regulated Multi‐State Long‐Lived Emission from Star‐Shaped Molecules
Authors: Li Yiran , Baryshnikov Glib V. , Siddique Farhan , Wei Peng , Wu Hongwei , Yi Tao 
Published: October 2022

AbstractHow to utilize molecular vibration to tune triplet‐involved emissions in multiple states is highly challenging. Here, star‐shaped triphenylamine derivatives have been employed as model systems to understand how molecular vibration affects thermally activated delayed fluorescence (TADF) and room temperature phosphorescence (RTP) emissions in multiple states. Nonplanar, star‐shaped conformations allow molecules to generate appropriate vibrations in the solution state, facilitating vibronic coupling between their T1and T2states to generate effective TADF. More importantly, a relatively dispersed state can allow the molecules to efficiently vibrate in the solid state, and a crystalline environment further promotes a more efficient TADF. Lastly, by suppressing molecular vibration to inhibit the TADF, ultra‐long RTP was observed upon doping these molecules into polymers. These molecules can be used in information encryption and storage as well as bioimaging.
Phase change composites derived from chromium‐containing leather solid waste for efficient solar‐thermal energy storage
Authors: Wang Jiuao , Chai Xiaowei , Guo Jun , Wang Haibo , Du Zongliang , Cheng Xu , Du Xiaosheng 
Published: October 2022

AbstractLarge amounts of chromium‐containing leather solid waste (CLSW) generated in conventional leather making industry. The high value‐added transformation of CLSW has attracted lots of attention from scientists and technologists. Herein, gelatin was extracted from CLSW through alkaline hydrolysis dechroming and decalcification process. Then, form‐stable phase change material composites (GMPCMs) based on gelatin, n‐docosane, and melanin were designed and fabricated through impregnating n‐docosane into gelatin/melanin hybrid aerogels (GMAs). The three‐dimensional (3D) honeycombed aerogels GMAs with ultralow density and extremely high surface area can perfectly support n‐docosane and prevent liquid leakage. As expected, the solar‐thermal conversion efficiency of GMPCMs (up to 84.8%) was significantly increased with the introduction of melanin in PCM composites. DSC analysis indicated that GMPCMs possessed relatively large thermal energy storage density and the melting enthalpy of GMPCMs ranged from 207.1 to 228.0 J/g. Furthermore, GMPCMs showed admirable shape stability, excellent encapsulation capacity, and satisfactory thermal reversibility.
Zn‐Sb Bimetallic Electrocatalyst Enhances the Conversion of CO2 to Formate
Authors: Liu Wenhui , Li Wenjuan , Zhang Zhengrong , Cao Zhiyuan , Huo Shengjuan 
Published: October 2022

AbstractIt was discovered the bimetallic Zn−Sb nanoparticles supported on carbon nanotubes can electrocatalyze CO2 into formate efficiently, comprising the best performance to date for Sb‐based catalysts under moderate overpotential. This project was accomplished by a versatile two‐step alcoholysis precipitation strategy with tunable Zn : Sb ratios, and the performance of optimized Zn2.33Sb0.67O4 was locked in the electrochemical CO2 reduction reaction. During the subsequent electrolysis, the mixed phases of metallic Zn and Sb served as active centers. The Zn−Sb heterostructure and the electron relocation were confirmed. By means of interactions and possible additional binding sites for reaction intermediate *OCHO, the material displayed different catalytic properties from either Zn or Sb, and was selective for formate up to 92%, which was ca. 6.1 times or 4.6 times than that of each single component. The encouraging results highlight the power of the interaction between binary metallic components to synergistically electrocatalyze CO2 conversion.
Exact likelihood ratio and Wald tests for the balanced joint progressive censoring scheme
Authors: Mondal Shuvashree , Kundu Debasis 
Published: October 2022

AbstractRecently, the balanced joint progressive censoring (BJPC) for two samples has been introduced by the authors. This work comprises of developing testing of hypothesis for the BJPC scheme. An exact likelihood ratio test is developed to test the ratio of mean life times of two different products through joint life testing experiment. Along with this development, the Wald test has also been discussed, and an approximate power function has been used for power computation. Along with the study of testing of hypothesis, the optimal censoring scheme based on the power of the proposed tests has been determined. Meta heuristic variable neighborhood algorithm is exploited in this optimization task.
Bioanalytical methods for pharmacokinetic studies of antileishmanial drugs
Authors: Roseboom Ignace C. , Rosing Hilde , Beijnen Jos H. , Dorlo Thomas P. C. 
Published: October 2022

AbstractBioanalytical method development and validation for the quantification of antileishmanial drugs are pivotal to support clinical trials and provide the data necessary to conduct pharmacokinetic (PK) analysis. This review provides a comprehensive overview of published validated bioanalytical assays for the quantification of antileishmanial drugs amphotericin B, miltefosine, paromomycin, pentamidine, and pentavalent antimonials in human matrices. The applicability of the assays for leishmaniasis clinical trials as well as their relevance to PK studies with emphasis on the choice of matrix, calibration range, sample volume, sample preparation, choice of internal standards, separation, and detection was discussed for each antileishmanial drug. Given that no published bioanalytical methods included multiple antileishmanial drugs in a single assay although antileishmanial shortened combination regimens currently were under investigation, it was recommended to combine various drugs in a single bioanalytical method. Furthermore, bioanalytical method development regarding target site matrix as well as applying microsampling strategies was recommended to optimize future clinical PK studies in leishmaniasis.
Patient‐reported disruptions to cancer care during the COVID‐19 pandemic: A national cross‐sectional study
Authors: Lang Jacob J. , Narendrula Aparna , Iyer Sharanya , Zanotti Kristine , Sindhwani Puneet , Mossialos Elias , Ekwenna Obi 
Published: October 2022

AbstractBackgroundThe aim of this study is to evaluate the extent and associations with patient‐reported disruptions to cancer treatment and cancer‐related care during the COVID‐19 pandemic utilizing nationally representative data.MethodsThis analysis uses data from the 2020 National Health Interview Survey (NHIS), an annual, cross‐sectional survey of US adults. Adults (age >18) who reported requiring current cancer treatment or other cancer‐related medical care in the second half of 2020 were included. Estimated proportions of patients with self‐reported changes, delays, or cancelations to cancer treatment or other cancer care due to the COVID‐19 pandemic were calculated using sampling weights and associations with sociodemographic and other health‐related variables were analyzed.ResultsIn total, 574 (sample‐weighted estimate of 2,867,326) adults reported requiring cancer treatment and/or other cancer care since the start of the COVID‐19 pandemic. An estimated 32.1% reported any change, delay, or cancelation. On sample‐weighted univariable analysis, patients who were younger, female, had one or fewer comorbidities, and uninsured were significantly more likely to report disruptions. On sample‐weighted, multivariable analysis, patients who were younger and female remained significant predictors. Nearly 90% of patients included in the study reported virtual appointment use. Patients reporting disruptions were also significantly more likely to report feelings of anxiety.ConclusionsAn estimated 1/3 of patients experienced disruptions to cancer care due to the COVID‐19 pandemic. Patients experiencing disruptions in care were more likely to be female or younger which may reflect risk stratification strategies in the early stages of the pandemic, and also had higher rates of anxiety. The longitudinal impact of these disruptions on outcomes merits further study.
Initial active surveillance for patients with metastatic renal cell carcinoma: 10 years' experience at a regional cancer Centre
Authors: Stares Mark , Chauhan Vishwani , Moudgil‐Joshi Jigi , Kong Qiu G. , Malik Jahangeer , Sundaramurthy Aravindhan , Elliott Tony , Mains Edward , Leung Steve , Laird Alexander , Symeonides Stefan N. 
Published: October 2022

AbstractA subset of patients with metastatic renal cell carcinoma (mRCC) follow an indolent disease course and may benefit from initial active surveillance (AS). However, selecting patients suitable for this approach is challenging. To investigate this we sought to define outcomes of patients with mRCC suitable for initial AS. All patients with mRCC clinically selected for initial AS at the Edinburgh Cancer Centre between January 2010 and December 2020 were identified. Key inflammatory biomarkers (haemoglobin, white cell count, neutrophil count, platelets, C‐reactive protein [CRP], albumin, corrected calcium) and the International Metastatic RCC Database Consortium (IMDC) risk score were measured. The relationship between these and time to systemic anticancer therapy (tSACT) and overall survival (OS) was analysed. Data were available for 160 patients. Estimated median overall survival was 88.0 (interquartile range [IQR] 34.0–127.0) months. Median tSACT was 31.8 (IQR 12.0–76.3) months. On multivariate analysis, only CRP was predictive of tSACT (HR 2.47 [95% CI:1.59–3.85] p < 0.001) and OS (HR 3.89 [95% CI:2.15–6.83] p < 0.001). Patients with CRP > 10 mg/L were more likely to commence SACT within 1 year than those with CRP≤10 mg/L (41% vs. 18%, Relative Risk 2.16 (95% CI:1.18–3.96) (p = 0.012)). IMDC risk score was not predictive of tSACT or OS. Active surveillance is an appropriate initial management option for selected patients with mRCC. CRP, a biomarker of systemic inflammation, may provide additional objective information to assist clinical decision‐making in patients with mRCC being considered for initial AS. Although this is a retrospective observational study, the cohort is well defined and includes all patients managed with initial AS in an inclusive real‐world setting.
Phelliribsin B: A New Styrylpyrone Derivative from the Medicinal Fungus Phellinus ribis
Authors: Ren Wenjing , Bao Mengyu , Zhang Jin , Cao Yanhua , Duan Baoguo , Xu Lingchuan , Liu Yuhong 
Published: October 2022

AbstractA novel styrylpyrone derivative, named phelliribsin B (1), as well as four biogenetically related known compounds, phellifuropyranone A (2), inoscavin C (3), inoscavin A (4), and inoscavin D (5) were separated and purified from the medicinal fungus Phellinus ribis. The structure of phelliribsin B was determined by spectroscopic analysis, and the absolute configuration was assigned by experimental and calculated ECD data. Additionally, the plausible biosynthetic pathway of 1 was also proposed. Compound 1 showed moderately cytotoxic activity against HepG2 and SKOV‐3 tumor cell lines with IC50 values of 32.71 and 57.89 μM, respectively. Based on the results of cytotoxicity against HepG2 tumor cells, the structure‐activity relationship of compounds 1–4 with similar skeletons was discussed. The styrylpyrone derivatives with similar skeletons have moderately cytotoxic activity and have the potential to play an important role in the anti‐tumor treatment.
Severe osteoporosis as atypical presentation of hereditary hemochromatosis
Authors: Taujan Georgiana Cristina , Iconaru Laura , Rosu Mihaela , Kosmopoulou Olga Ana , Papadopoulou Ioana Blerta , Baleanu Felicia 
Published: October 2022

AbstractBesides important metabolic repercussions, iron overload is reported to be associated with deleterious effects on articulations and bones. We present the case of a male patient diagnosed with severe osteoporosis and vertebral fracture, in whom the evaluation for secondary osteoporosis revealed hereditary hemochromatosis.
Atypical Guillain–Barre syndrome with T6 sensory level
Authors: Al‐Ameen Osamah , Faisal Mohanad , Mustafa Salma , Alhatou Mohammed 
Published: October 2022

AbstractGuillain–Barré syndrome is an acute immune‐mediated demyelinating disease. Typical features include progressive ascending lower extremity weakness and areflexia. Several variants have been described that can make the diagnosis challenging. Here, we report a case of GBS presenting with progressive lower limb weakness and T6 sensory level.
Coming down the “chimney”: Percutaneous coronary intervention on a post‐transcatheter aortic valve replacement with valve‐in‐valve patient
Authors: Taleb Adam 
Published: October 2022

AbstractAccessing the coronary arteries post‐transcatheter aortic valve replacement is a growing challenge. This is a case of a patient requiring percutaneous coronary intervention on a left circumflex artery after a TAVR valve‐in‐valve and a left main “chimney” stent, describing all the challenges met during the procedure.
Intermediate syndrome following organophosphate poisoning: A case report in a low resource and poor socio‐economic setting
Authors: Lageju Nimesh , Neupane Durga , Jaiswal Lokesh Shekher , Chapagain Suresh , Uprety Pratik , Regmi Swapnil , Bhandari Silan 
Published: October 2022

AbstractIntermediate syndrome with respiratory failure is a serious complication that can be fatal as in our case of a 24‐year‐old‐man who developed intermediate syndrome requiring intubation and respiratory support. Furthermore, the patient's socio‐economic situation significantly impacts the illness's progress and prognosis.
Molecular Mechanism of Substrate Oxidation in Lytic Polysaccharide Monooxygenases: Insight from Theoretical Investigations
Authors: Hagemann Marlisa M. , Hedegård Erik D. 
Published: October 2022

AbstractLytic polysaccharide monooxygenases (LPMOs) are copper enzymes that today comprise a large enzyme superfamily, grouped into the distinct members AA9–AA17 (with AA12 exempted). The LPMOs have the potential to facilitate the upcycling of biomass waste products by boosting the breakdown of cellulose and other recalcitrant polysaccharides. The cellulose biopolymer is the main component of biomass waste and thus comprises a large, unexploited resource. The LPMOs work through a catalytic, oxidative reaction whose mechanism is still controversial. For instance, the nature of the intermediate performing the oxidative reaction is an open question, and the same holds for the employed co‐substrate. Here we review theoretical investigations addressing these questions. The applied theoretical methods are usually based on quantum mechanics (QM), often combined with molecular mechanics (QM/MM). We discuss advantages and disadvantages of the employed theoretical methods and comment on the interplay between theoretical and experimental results.
Use of cyclopentyl methyl ether (CPME) as green membrane for acetic acid removal by facilitated bulk liquid membrane: A transport and kinetic study
Authors: Baylan Nilay , Türk Feride Naime , Çehreli Süheyla 
Published: October 2022

AbstractIn current investigation, cyclopentyl methyl ether (CMPE) was tested as a novel membrane solvent for acetic acid removal from an aqueous medium in the facilitated bulk liquid membrane (BLM). Tributyl phosphate (TBP) has been utilized as a carrier in CMPE to facilitate acetic acid transport. The influences of various operating factors like carrier concentration in the membrane solvent, receiving phase type, and receiving phase concentration on removal, were analyzed. The uptake was evaluated by means of feed (extraction) and receiving yields. Following this, a mass transfer modelling was established and the mass transfer coefficients were determined. The maximum yields were recorded as 95.4% for extraction and 78.01% for receiving yields at 2 mol · L−1 carrier concentration in membrane solvent, and 4 mol · L−1 NaOH of receiving phase concentration.
Biopolymer‐Based Aerogels for Electromagnetic Wave Shielding and Absorbing
Authors: Han Mingrui , Zhang Runa , Wu Qilei , Wu Na , Liu Jiurong 
Published: October 2022

Comprehensive SummaryThe rapid development of communication technology and electronic industry has brought unprecedented serious electromagnetic interference (EMI) and electromagnetic wave (EMW) pollution. Although EMI shields and EMW absorbers based on metal or magnetic materials were used to solve these problems, they have long been criticized for their high price, high density and easy corrosion. In order to achieve low density and efficient dissipation of electromagnetic energy, aerogels stand out among manifold materials. However, constructing aerogels with good EMI shielding or EMW absorption performance and acceptable mechanical properties is not an easy task. Burgeoning biopolymers, such as cellulose, lignin, chitin/chitosan and alginate, breathe new life into aerogels for high‐efficiency EMW shielding and absorbing. Here, we reviewed the contributions of biopolymers in the fields of aerogels for EMW shielding and absorbing. At the same time, some challenges and outlook were also pointed out, aiming to promote the advance of aerogel‐based EMI shields and EMW absorbers as well as the rational utilization of biopolymers.