bluuebunny/crossref_metadata_2025_split huggingface dataset:
See‐and‐treat in‐office hysteroscopy versus operative hysteroscopy for the treatment of retained products of conception: A retrospective study
Authors: Raz Nili , Sigal Emiliya , Gonzalez Arjona Fernando , Calidona Carmelo , Garzon Simone , Uccella Stefano , Laganà Antonio Simone , Haimovich Sergio 
Published: June 2022

AbstractAimTo compare the efficacy and safety of in‐office hysteroscopy with a see‐and‐treat approach with that of operative hysteroscopy for the treatment of retained products of conception (RPOC).MethodsWe retrospectively identified all consecutive patients who underwent hysteroscopic treatment of RPOC between 2015 and 2019. We excluded patients with RPOC larger than 2 cm at preoperative transvaginal ultrasounds. Between 2015 and 2017, all hysteroscopic removals of RPOC were performed by operative hysteroscopy. Between 2018 and 2019, all cases of RPOC less than 2 cm in size were hysteroscopically removed by the see‐and‐treat approach in the office setting. Sociodemographic, clinical, and procedure characteristics along with complications were retrieved from medical records.ResultsBetween 2015 and 2019, 119 women underwent hysteroscopic removal of RPOC equal to or smaller than 2 cm: 53 patients by in‐office hysteroscopy, and 66 by operative hysteroscopy. The two groups were similar in preoperative characteristics. Although the time required to complete the RPOC removal was similar, the total procedure and assistant time were significantly higher in the operative hysteroscopy group (p < 0.001). Moreover, operative hysteroscopy was associated with a higher proportion of cases complicated by excessive bleeding, cervical tear, or uterine perforation (p = 0.016). Failure to complete the procedure was similarly reported in the two groups (p = 0.58).ConclusionsIn‐office hysteroscopy with the see‐and‐treat approach for RPOC equal to or smaller than 2 cm appears as effective as operative hysteroscopy, but safer. In‐office hysteroscopy may be considered the first choice for treating RPOC equal to or smaller than 2 cm.
Alterations in kinematics of temporomandibular joint associated with chronic neck pain
Authors: Siu Weng‐Sam , Shih Yi‐Fen , Lee Shyh‐Yuan , Hsu Chih‐Yu , Wei Min‐Ju , Wang Tzyy‐Jiuan , Lin Hsiu‐Chen , Lin Yin‐Liang 
Published: June 2022

AbstractBackgroundTemporomandibular disorder (TMD) is an umbrella term for pain and dysfunction of the temporomandibular joint (TMJ) and its associated structures. Patients with TMD show changes in TMJ kinematics and masticatory muscle activation. TMD is commonly comorbid with non‐specific chronic neck pain (NCNP), which may be one of the risk factors for TMD.ObjectivesThis study aimed to investigate whether patients with NCNP have altered TMJ kinematics and masticatory muscle activity.MethodsThis was a cross‐sectional exploratory study including 19 healthy participants and 20 patients with NCNP but without TMD symptoms. TMJ kinematics was measured during mouth opening and closing, jaw protrusion and jaw lateral deviation. Surface electromyography was used to record the muscle activity of the anterior temporalis, masseter, sternocleidomastoid and upper trapezius while clenching. Furthermore, cervical posture, cervical range of motion (ROM) and pressure‐pain threshold of the neck and masticatory muscles were measured.ResultsCompared with the healthy group, the NCNP group showed significantly reduced upper cervical rotation ROM (p = .041) and increased condylar path length (p = .02), condylar translation (opening p = .034, closing p = .011) and mechanical pain sensitivity of the upper trapezius (p = .018). Increased condylar translation was significantly correlated with reduced upper cervical mobility and poor cervical posture (r = −0.322 to −0.397; p = .012–.046).ConclusionIncreased condylar translation and path length in patients with NCNP may indicate poor control of TMJ articular movement, which may result from neck pain or may be a compensation for limited neck mobility. Evaluation of excessive TMJ translation may be considered in patients with NCNP.
Strange themes in pandemic dreams: Insomnia was associated with more negative, anxious and death‐related dreams during the COVID‐19 pandemic
Authors: Meaklim Hailey , Burge Malisa , Le Flora , Bains Sukjhit K. , Saunders William , Ghosh Stephen , Junge Moira F. , Varma Prerna , Rehm Imogen C. , Jackson Melinda L. 
Published: June 2022

SummaryDreaming and insomnia are important markers of distress in times of crisis. Here, we present a longitudinal, mixed‐methods study examining changes in dreaming between individuals with and without insomnia symptoms and their relationship to mental health during the COVID‐19 pandemic. A global survey examining insomnia symptoms, dreams and mental health was launched in April 2020 and followed participants over 12 months. Of 2240 participants, 1009 (45%) reported dream changes at baseline. A higher proportion of participants with new‐onset insomnia reported dream changes (55%) than those with pre‐existing insomnia (45%) or good sleepers (36%). Overall, thematic analysis identified key dream change themes of increased dream activity, with participants dreaming vividly, in high‐definition, and with a strong negative charge. Themes around survival, adjusting to pandemic life, meaning‐making and poor sleep quality were also noted. Linguistic Inquiry Word Count showed that individuals with insomnia used more negative words to describe their dream changes than good sleepers. Specifically, the new‐onset insomnia group used more anxious and death‐related words than those who slept well. Notably, all groups experienced a significant reduction in dream activity by 3‐month follow‐up. Lastly, dream changes were associated with worse mental health symptoms over time, and this effect was more pronounced in individuals with insomnia. Our results highlight that insomnia symptoms, especially new‐onset insomnia, are associated with more negative dream changes during collective stressful events, potentially compounding daytime distress and mental health symptoms over time. During times of crisis, dreaming and insomnia may reveal an important target for mental health interventions.
Effect of the personal protective equipment donning and doffing program for nurses in military hospitals
Authors: Lee Hyewon , Jeong Ihn Sook 
Published: June 2022

AbstractThis study aimed to develop and verify the effect of a new personal protective equipment donning and doffing program for nurses in military hospitals. A total of 40 nurses (20 experimental group, 20 control group) participated in this nonequivalent control group experimental study. The new program consisted of the description of the design modification of the inner and outer boundary marks of coveralls and a video with verbal instructions and footswitch that the participants could watch at their own pace. Data collection was carried out before, immediately after, and 2 weeks after the intervention. The effects of the program on accuracy, self‐efficacy, and time were analyzed using a generalized estimating equation. PPE donning and doffing accuracy, self‐efficacy, and time were significantly increased in the experimental group compared to those in the control group, both immediately after and 2 weeks after intervention. As this program has been confirmed to be effective in improving PPE donning and doffing accuracy and self‐efficacy, we recommend using this program for training nurses on donning and doffing of PPE.
A novel scalable electrode array and system for non‐invasively assessing gastric function using flexible electronics
Authors: Gharibans Armen A. , Hayes Tommy C. L. , Carson Daniel A. , Calder Stefan , Varghese Chris , Du Peng , Yarmut Yaara , Waite Stephen , Keane Celia , Woodhead Jonathan S. T. , Andrews Christopher N. , O'Grady Greg 
Published: June 2022

AbstractBackgroundDisorders of gastric function are highly prevalent, but diagnosis often remains symptom‐based and inconclusive. Body surface gastric mapping is an emerging diagnostic solution, but current approaches lack scalability and are cumbersome and clinically impractical. We present a novel scalable system for non‐invasively mapping gastric electrophysiology in high‐resolution (HR) at the body surface.MethodsThe system comprises a custom‐designed stretchable high‐resolution “peel‐and‐stick” sensor array (8 × 8 pre‐gelled Ag/AgCl electrodes at 2 cm spacing; area 225 cm2), wearable data logger with custom electronics incorporating bioamplifier chips, accelerometer and Bluetooth synchronized in real‐time to an App with cloud connectivity. Automated algorithms filter and extract HR biomarkers including propagation (phase) mapping. The system was tested in a cohort of 24 healthy subjects to define reliability and characterize features of normal gastric activity (30 m fasting, standardized meal, and 4 h postprandial).Key ResultsGastric mapping was successfully achieved non‐invasively in all cases (16 male; 8 female; aged 20–73 years; BMI 24.2 ± 3.5). In all subjects, gastric electrophysiology and meal responses were successfully captured and quantified non‐invasively (mean frequency 2.9 ± 0.3 cycles per minute; peak amplitude at mean 60 m postprandially with return to baseline in <4 h). Spatiotemporal mapping showed regular and consistent wave activity of mean direction 182.7° ± 73 (74.7% antegrade, 7.8% retrograde, 17.5% indeterminate).Conclusions and InferencesBSGM is a new diagnostic tool for assessing gastric function that is scalable and ready for clinical applications, offering several biomarkers that are improved or new to gastroenterology practice.
Genome‐enabled discovery of candidate virulence loci in Striga hermonthica, a devastating parasite of African cereal crops
Authors: Qiu Suo , Bradley James M. , Zhang Peijun , Chaudhuri Roy , Blaxter Mark , Butlin Roger K. , Scholes Julie D. 
Published: June 2022

Summary

Parasites have evolved proteins, virulence factors (VFs), that facilitate plant colonisation, however VFs mediating parasitic plant–host interactions are poorly understood. Striga hermonthica is an obligate, root‐parasitic plant of cereal hosts in sub‐Saharan Africa, causing devastating yield losses. Understanding the molecular nature and allelic variation of VFs in S. hermonthica is essential for breeding resistance and delaying the evolution of parasite virulence.

We assembled the S. hermonthica genome and identified secreted proteins using in silico prediction. Pooled sequencing of parasites growing on a susceptible and a strongly resistant rice host allowed us to scan for loci where selection imposed by the resistant host had elevated the frequency of alleles contributing to successful colonisation.

Thirty‐eight putatively secreted VFs had very different allele frequencies with functions including host cell wall modification, protease or protease inhibitor and kinase activities. These candidate loci had significantly higher Tajima's D than the genomic background, consistent with balancing selection.

Our results reveal diverse strategies used by S. hermonthica to overcome different layers of host resistance. Understanding the maintenance of variation at virulence loci by balancing selection will be critical to managing the evolution of virulence as part of a sustainable control strategy.
Influence of periodontitis and diabetes on structure and cytokine content of platelet‐rich fibrin
Authors: Gupta Shipra , Jain Akanksha , Gupta Mili , Gupta Jyoti , Kansal Shubhangi , Bhansali Anil , Garg Sukant , Singla Mohita , Gupta Arpit , Gauba Krishan 
Published: June 2022

AbstractBackgroundPlatelet‐rich fibrin (PRF) is a second‐generation platelet concentrate with multiple applications in wound healing and regeneration in both periodontitis and diabetes. However, the three dimensional (3‐D) structure and cytokine content of PRF might be altered in patients suffering from either/both of the chronic inflammatory conditions, ultimately influencing the efficacy of PRF as a biomaterial for regenerative medicine.AimThe aim of the present study was hence to evaluate the effect of both these chronic inflammatory diseases on the 3‐D structure of PRF membrane. An attempt was also made to compare the growth factor content between the plasma and RBC ends of the prepared PRF gel.Materials & MethodsL‐PRF was prepared for twenty participants, healthy (5), periodontitis (5), T2DM (5) and T2DM with periodontitis (5). Porosity and fiber diameter of PRF membranes was visualized under FE‐SEM and measured using ImageJ Software. PDGF‐BB and TGF‐β1 levels in PRF gel were assessed by ELISA.ResultsThe average diameter of fibrin fibers under FE‐SEM was 0.15 to 0.30 micrometers. Porosity was higher at the plasma end (p = 0.042). Red blood cell (RBC) end of the membrane had thinner fibers arranged in a comparatively more dense and compact structure with smaller porosities. Healthy subjects had the least porous PRF compared to subjects with either/both of the chronic conditions. PDGF‐BB levels were similar along all the four groups. TGF‐β1 levels were highest in healthy subjects.Discussion3‐D structure and growth factor content of PRF are influenced by a person's periodontal and/or diabetic status. The RBC end of the PRF membrane, as compared to the plasma end, has thinner fibers arranged in a comparatively more dense and compact structure with smaller porosities, and hence should be favored during periodontal regenerative procedures.ConclusionBoth periodontitis and diabetes have a significant influence on the 3‐D structure and growth factor content of PRF produced.
Should Diastatic Syndesmosis be Stabilized in Advanced Pronation‐External Rotation Ankle Injuries? A Retrospective Cohort Comparison
Authors: Wu Chi‐chuan , Yeh Wen‐ling , Lee Po‐cheng , Chou Ying‐chao , Hsu Yung‐heng , Yu Yi‐hsun 
Published: June 2022

AbstractObjectiveWith or without screw stabilization for diastatic syndesmosis in advanced pronation‐external rotation (PE) ankle injuries has not yet been well‐determined. Both techniques were retrospectively compared to investigate the superiority of either of the two.MethodsA retrospective cohort study was carried out. From January 1, 2008, to December 31, 2017, 81 consecutive adult patients (average, 42 years; range, 18–78 years; 44 men and 37 women) with advanced PE ankle injuries (stage 3 or 4 PE type) were treated. After malleolar fractures were internally stabilized with screws and plates, the syndesmotic stability was rechecked by external rotation and hook tests. The necessity of cortical screw insertion to stabilize diastatic syndesmosis was decided by the individual orthopaedic surgeon. Postoperatively, a short leg splint was used for 6 weeks. The syndesmotic screw was removed based on the surgeon's policy. The removal of internal fixation for malleolar fractures was required after 1 year. The outcomes of both approaches were compared clinically, and ankle function was compared using the American Orthopaedic Foot and Ankle Society (AOFAS) score. For statistical comparison, the chi‐square test was used for categorical data and the Mann–Whitney U test was used for numerical data.ResultsSeventy‐one patients (average, 40 years; range, 18–78 years; 40 men and 31 women) were followed for at least 1 year (87.7%; average, 2 years; range, 1–11 years). Group 1 (with syndesmotic stabilization) had 22 patients and Group 2 (without syndesmotic stabilization), 49 patients. The union rate in Group 1 patients was 100% (22/22), and in Group 2 patients, 91.8% (45/49; p = 0.17). One deep wound infection occurred in Group 1 patients and two in Group 2 patients. Syndesmosis re‐diastasis occurred in 13.6% (3/22) of Group 1 patients and 30.6% (15/49) of Group 2 patients (p = 0.13). One syndesmotic screw broke at 6 months. Satisfactory ankle function according to the AOFAS score was noted in 86.4% (19/22) of Group 1 patients and 65.3% (32/49) of Group 2 patients (p = 0.07).ConclusionInsertion of syndesmotic screws to promote ligament healing after internal fixation of malleolar fractures in advanced PE ankle injuries may be reasonable.
Pulmonary hypertension with bronchopulmonary dysplasia: Aichi cohort study
Authors: Kawai Yuri , Hayakawa Masahiro , Tanaka Taihei , Yamada Yasumasa , Nakayama Atsushi , Kato Yuichi , Kouwaki Masanori , Kato Takenori , Tanaka Ryo , Muramatsu Kanji , Hayashi Seiji , Yamamoto Hikaru , Takemoto Koji , Ieda Kuniko , Nagaya Yoshiaki , Honda Shigeru , Shinohara Osamu , Funato Yusuke , Kokubo Minoru , Imamine Hiroki , Miyata Masafumi 
Published: June 2022

AbstractBackgroundThe incidence of pulmonary hypertension (PH) associated with bronchopulmonary dysplasia (BPD) has not been investigated in regional cohorts. The aim of this study was to clarify the incidence of PH associated with BPD in all very low birthweight infants (VLBWIs) born during the study period in Aichi Prefecture, Japan.MethodsWe conducted a retrospective observational cohort study of all VLBWIs born in Aichi Prefecture. The inclusion criteria were VLB, birth between 1 January 2015 and 31 December 2015, and admission to any neonatal intensive care unit in Aichi Prefecture. BPD28d and BPD36w were defined as the need for supplemental oxygen or any respiratory support at 28 days of age or 36 weeks of postmenstrual age (PMA). The primary outcome was the incidence of PH after 36 weeks’ PMA (PH36w) in VLBWIs with BPD28d and BPD36w. The secondary outcomes were the clinical factors related to PH36w in BPD36w patients. Mann–Whitney U‐test and Fisher’s exact test were used for univariate analysis. Differences were considered statistically significant at P < 0.05. Risk ratio (RR) and 95% confidence interval (CI) were also evaluated.ResultsA total of 441 patients were analyzed. A total of 217 and 131 patients met the definition of BPD28d and BPD36w, respectively. Nine patients were diagnosed with PH36w (4.2% and 6.9% of the BPD28d and BPD36w patients, respectively). The presence of oligohydramnios (RR, 2.71; 95% CI: 1.55–4.73, P = 0.014) and sepsis (RR, 3.62; 95% CI: 1.51–8.63, P = 0.025) was significant in the PH36w patients.ConclusionsThe incidence of PH36w was 4.2% and 6.9% in the BPD28d and BPD36w patients, respectively. Oligohydramnios and sepsis were significantly associated with PH36w in VLBWIs.
Unknown effects of daily‐scale solar activity on the plant growth: Data from 6‐year growth monitoring of Sphagnum riparium
Authors: Mironov Victor L. 
Published: June 2022

AbstractThe influence of solar activity on plant growth has been studied for over 100 years, however, this phenomenon is still poorly understood on a daily scale. The data from extensive monitoring of the growth of peat moss Sphagnum riparium, which we are conducting in the mires of Karelia (Russia), may shed light on this issue. During the 6 years of observation, 161,190 shoots were measured, and 1075 growth rates were obtained. Considering together the growth rates with the sunspot number and involving data on seasonal temperature, we found previously unknown effects of daily‐scale solar activity on plant growth. It was found that the sunspot number weakly but significantly inhibits the growth of Sphagnum. The extreme sunspot number in the 4 days before the growth rate values have a stronger influence. The involvement of temperature data showed that inhibition in growth is observed only in the temperature range from 6.7°C to 15.3°C and disappears beyond these limits. In addition, the data obtained showed that the influence of sunspot number on the growth of Sphagnum is progressively increasing along the gradient from the minimum to the maximum of the 11‐year solar cycle. The study provides one of the first results on the effect of solar activity on plant growth on a daily scale. The results expand our knowledge of the biological effects of solar activity. Indirectly, they can also be useful to better our understanding of the ozone layer's involvement in this process.
Motivated for movement: Beta activation over the motor cortex resulting from intrinsic and extrinsic motivators
Authors: Wilhelm Ricardo A. , Threadgill A. Hunter , Gable Philip A. 
Published: June 2022

AbstractPast work on motivation has primarily studied dichotomous distinctions of motivation (e.g., extrinsic or intrinsic). However, focusing on the overall motivational intensity may be better at accentuating the unique differences within and between varying motivators as it pertains to the impetus to act. Specifically, motivational intensity influences neural patterns of beta band frequency (13–30 Hz) as measured by electroencephalography (EEG) that enable motor‐action preparation, a neural correlate of motivated movement. The primary aim of across three experiments was to investigate neural motor‐action preparation to modified flanker tasks within achievement (Experiment 1), autonomous (Experiment 2), and extrinsic vs. intrinsic (Experiment 3) motivational contexts. Experiment 1 revealed greater motor‐action preparation for challenging trial cues and did not differ in behavioral attentional and performance measures across both trial types. Experiment 2 revealed no significant difference in motor‐action preparation, did not differ in behavioral attentional narrowing and had worse behavioral performance in high autonomy relative to low autonomy trials. Experiment 3 revealed greater motor‐action preparation for challenging trial cues, did not differ in behavioral attentional narrowing and had a faster performance for reward trials relative to high autonomy trials. These findings suggest motivators of the same category (i.e., intrinsic) may differ in motivational strength, as suggested by a neurophysiological measure of immediate motivated movement planning.
How status‐group power differentials shape age discrimination within U.S. federal agencies: Evidence from EEOC formal complaint filings, 2010–2019
Authors: Krause George A. , Park Jungyeon 
Published: June 2022

AbstractAge discrimination is a systemic problem of the American administrative state that undermines both the caliber and performance of the U.S. federal government workforce. A theory is proposed, anchored on discrimination against age‐eligible employees (age 40 and over) representing a social identity group, to explain how status‐group power differentials between supervisors and non‐supervisors within U.S. federal agencies explain the organizational incidence of formal discrimination complaints. The theory predicts that the incidence of age discrimination formal complaints is declining in the share of supervisory personnel who are discrimination age‐eligible while increasing in the share of non‐supervisory personnel members who belong to this group. Evidence is obtained for these hypotheses using objective data on Equal Employment Opportunity Commission's age discrimination formal complaints about an unbalanced panel of 130 U.S. federal agencies between 2010 and 2019. The empirical evidence underscores the structural challenges to combatting ageism within the U.S. federal government workforce during an era of an intergenerational personnel change.
Chinese Buddhist narratives of wonders: Recent studies and approaches
Authors: Ho Chiew Hui 
Published: June 2022

AbstractApart from their immediate religious import, the value of Chinese Buddhist narratives as alternative historical and documentary sources for understanding Buddhism and Chinese religion has not been appreciated until recently. Besides introducing early research on Chinese Buddhist narratives, this article focuses mainly on two recent studies of medieval Chinese Buddhist tales to illustrate how this body of indigenous literature could be an important source of religious history, providing information not found in normative canonical Buddhist writings. Both studies feature significant moves toward a more nuanced and interdisciplinary approach to this genre of Buddhist literature. They recognize the complex socio‐religious contexts in which the tales emerged and circulated, especially in relation to the role played by historical agents, which can be explored fruitfully in relation to the narratives through a combination of different methods.