bluuebunny/crossref_metadata_2025_split huggingface dataset:
Principios activos de origen biológico para favorecer la inocuidad en frutas y hortalizas.
Authors: Chimborazo Sara Sisa , Quille Daniela , Sánchez Estefanía , Jácome Pilco Carlos 
Published: November 2022

En la actualidad ha surgido la necesidad de buscar alternativas de conservación de alimentos, en respuesta a la necesidad de reducir los riesgos de contaminación asociados con la producción y comercialización de las frutas y hortalizas frescas, como mecanismo para generar mayores oportunidades de mercado. En este articulo presentamos información debidamente sistematizada de investigaciones referidas al desarrollo de productos de origen biológico, que se utilizan para la inocuidad de alimentos. El principal objetivo del procesamiento de alimentos es proveer bienestar al ser humano por medio de alimentos seguros, nutricionalmente adecuados y cubrir las expectativas de sabor, aroma y apariencia, por lo cual el uso de principios activos de origen biológico implica el aislamiento, purificación, estabilización e incorporación de dichos compuestos a los alimentos con fines antimicrobianos, sin que afecte negativamente a las características sensoriales, por lo que ya no solo tendremos mayor seguridad, sino mejor calidad de los alimentos. La Organización de las Naciones Unidas para la Agricultura y la Alimentación (FAO) es el principal organismo de las Naciones Unidas especializado en los aspectos relacionados con la calidad e inocuidad de los alimentos en todas y cada una de las fases de producción, cosecha, almacenamiento, transporte, elaboración y comercialización de los alimentos, planteando un enfoque de la calidad y la inocuidad de los alimentos basado en la cadena alimentaria, reconociendo de tal manera que todos los que intervienen en la misma comparten la responsabilidad de abastecer de alimentos inocuos, sanos y nutritivos.
Efecto de concentraciones de miel de abeja en la producción de una conserva en almíbar con fruta de pitahayas (Hylocereus undatus) y (Cereus ocampis)
Authors: Zambrano Vélez María Isabel , Vera Arteaga Teddy Alfredo , Muñoz Cedeño María Lissette , Zambrano Delgado David Alejandro 
Published: November 2022

El objetivo principal de la investigación fue evaluar el efecto de tres concentraciones de miel de abeja en la producción de una conserva en almíbar con fruta de pitahayas (Hylocereus undatus) y (Cereus ocampis). Se utilizó un Diseño Completamente al Azar con arreglo factorial AxB. Para la comparación de promedios de los tratamientos se utilizó la prueba de TUKEY al (p<0,05) de acuerdo a los resultados del ANOVA (pH y °Brix), para el análisis sensorial se aplicó una estadística no paramétrica utilizando la prueba de Kruskal Wallis y la comparación de promedios (en los casos de significancia estadísticamente) mediante el test de U Mann-Whitney. Los resultados del pH de las conserva de pitahayas indicaron que existió significancia estadística al (p< 0,05); obteniendo valores de pH en un rango de 4,55 a 4,96 y en los °Brix finales no existió significancia estadística. Se midió la estabilidad del almíbar de la miel de abeja donde el tratamiento A1B1 y A1B3 alcanzaron su estabilidad a los 28 días obteniendo 14,2 y 18,1° Brix finales. Los tratamientos A1B2, A2B1, A2B2 y A2B3 se llevaron 30 días en alcanzar la estabilidad de los sólidos solubles con resultados de 18,1, 14,7, 18,1 y 22,1°Brix. En el análisis organoléptico existió significancia al (p< 0,05) para el atributo olor y textura, y con respecto al sabor, color y apariencia fue no significativo. Los análisis microbiológicos realizados al producto de mayor aceptación tuvieron valores aceptables dentro de los parámetros que estipula la Norma INEN 1529. Se obtuvo efecto favorable con el uso de miel de abeja en el almíbar porque ayudó a mantener mejor las conservas de pitahaya gracias a sus propiedades conservantes.
Simulación del modelo matemático de proliferación de células resistentes a la quimioterapia usando GEOGEBRA
Authors: Espinoza Juan de Dios 
Published: November 2022

formal a temas biológicos y estudiar a profundidad temas complejos como lo es la enfermedad del cáncer, en donde los científicos han sumado esfuerzos usando la Matemática como fortaleza en la investigación. De acuerdo a estudios preliminares la resistencia que presentan las células cancerosas al efecto de la quimioterapia se ha podido modelar con una Ecuación Diferencial de primer orden con PVI y su simulación se lo ha contrastado con resultados obtenidos a través de datos experimentales. El GEOGEBRA es una herramienta computacional que permite desarrollar un análisis preliminar a modelos matemáticos basados en Ecuaciones Diferenciales que se puede contrastar con resultados analíticos, experimentales y también los obtenidos en otras herramientas computacionales como el MATLAB. En GEOGEBRA se muestran las soluciones particulares al modelo matemático de la proliferación de células resistentes a la quimioterapia, así como también confirma la eficacia del modelo mediante el campo direccional que arroja la ecuación y los resultados de predicción que presentan una tendencia a estabilizar la proliferación a un nivel de saturación y a un tiempo de duplicación de células pre establecido mediante parametrización en el programa computacional.
Comparison of Two Entry Methods for Laparoscopic Port Entry
Authors: Yadav R. P. , Paudyal N. , Bhattarai A. , Adhikari D. 
Published: November 2022

Background The first step in laparoscopic surgery is to establish the pneumoperitoneum for which many approaches have been introduced to minimize the complications. Although controversies exist regarding the most efficient technique, till now the best entry technique is still unsettled.
Objective To compare the safety, operating time and outcome of Direct Trocar Insertion with a well-established and widely practised Open Access Technique.
Method This is a prospective study at Nobel Medical College Teaching Hospital from November 2019 to February 2021. Patients were grouped into either of the two groups, Group 1 for Direct Trocar Insertion and Group 2 for Open Access Technique. They were later analysed for major and minor complications of the technique and a comparison of either method was done at the end of the study period.
Result A total of 823 patients were enrolled in the study. Among the study population, 411 patients had Direct Trocar Insertion while 412 patients had Open Access Technique. The majority of the operation that was done during the study period was laparoscopic cholecystectomy. Patients in the Open Access Technique group experienced more complications compared to Direct Trocar Insertion group.
Conclusion Despite the fear of adopting the Direct Trocar Insertion, this is a safe, better and quick technique for laparoscopic port entry. However, any surgeon practising laparoscopic surgery should be competent to adopt either technique to overcome failure in either process during port entry.
Taurine can Decrease Phosphorylated Tau Protein Levels in Alzheimer’s Model Rats’ Brains
Authors: Jahanshahi M. , Nikmahzar E. , Gorgani S. 
Published: November 2022

Background Microtubule formation is a dynamic process and Tau proteins promote the assembly of tubulin monomers into microtubules. Hyperphosphorylation of some amino acids in tau proteins causes neuron starvation and finally cell death. Taurine is found in the brain and has neuroprotective effects.
Objective Since the protective and therapeutic effects of Taurine on phosphorylated tau proteins level in the cerebellum and prefrontal cortex of rats induced by scopolamine have not been studied, we examined these effects.
Method Adult male Wistar rats were randomly distributed into nine groups. For two weeks, Taurine-treated rats received different doses of Taurine (25, 50, and 100 mg/kg/ day) before or after scopolamine injection. The phosphorylated tau protein level in the cerebellum and prefrontal cortex was determined by the enzyme-linked immunosorbent assay (ELISA) technique.
Result Pretreatment with three doses of Taurine significantly decreased the phosphorylated tau protein level that increased by scopolamine in the prefrontal cortex (p < 0.001), as well as the cerebellum (p < 0.001). Moreover, high-dose administration of Taurine (100 mg/kg/day) after scopolamine injection significantly decreased phosphorylated tau protein level in the cerebellum (p < 0.01), as well as the prefrontal cortex (p < 0.05). However, there was not any significant change in the level of phosphorylated tau protein after Taurine treatment (25 and 50 mg/kg/day) in the cerebellum and prefrontal cortex.
Conclusion It can be concluded that Taurine could attenuate the increase in phosphorylated tau protein induced by scopolamine in the brain of rats and usage of Taurine as a pretreatment complement could be more useful in the protection of neurons.
Clinical Profile and Conventional Risk Factors of Acute Coronary Syndrome in Late Elderly Patients
Authors: Simkhada Rabindra , Khan Barkadin , KC Sanjay Singh 
Published: November 2022

Background and Aims: Acute coronary syndrome is an important health issue. There is paucity of its data in late elderly. We aimed to study their clinical profile and prevalence of conventional risk factors.
Methods: Descriptive cross-sectional study conducted at Shahid Gangalal National Heart Centre from February 2022 to May 2022 including 71 consecutive patients of acute coronary syndrome of age >75 years. They were evaluated focusing their chief complaints and cardiovascular risk factors.
Results: Mean age was 80.32±4.06 years. Forty (56.33%) were male and 31 (43.66%) were female. Thirty-nine (54.92%) were hypertensive, 29 (40.84%) were diabetic, 18 (25.35%) were smoker, 10 (14.08%) had history of dyslipidemia and 6 (8.45%) had family history of cardiovascular disease. Chest pain was present in 54 (76.05%), dyspnea in 28 (39.43%), sweating in 15 (21.12%) and nausea/vomiting in 8 (11.26%). Palpitation was present in 7 (9.85%), and epigastric pain in 13 (18.30%). Seven (9.85%) gave history of pre-syncope/ syncope and 6 (8.45%) had altered mental status. There was significant correlation of smoking (p=0.02) and types of ACS (p=0.001) with gender.
Conclusion: Acute coronary syndrome were plausibility common in late elderly female. Chest pain was commonest complaint in both genders. Dyspnea, sweating and epigastric pain were also common. Pre-syncope/ syncope and altered mental status were also present in some cases. Conventional risk factors were quite common in both genders. These symptoms can be features acute coronary syndrome in elderly hence should be evaluated cautiously.
FORENSIC TESTIMONY AS A GENRE OF NARRATIVE DISCOURSE
Authors: Iegorova Anna V. 
Published: November 2022

Previous narrative researches have never focused on witnesses as the primary tellers of events in courtroom, but rather on lawyers. It stipulated the need to foreground the role of the witnesses who have first- hand knowledge of these events. To that end, this paper explores forensic testimonies from a new perspective and suggests to consider this type of institutional discourse as a separate kind of the narrative genre. In order to classify forensic testimonies as a genre of narrative discourse it was essential to provide a systematic review of contemporary literature related to the problem of genre definition with the aim of determining relevant criteria for assigning discourses specific generic affiliation. These criteria include: the institutional roles of the participants in courtroom context, the pragmatic goals of the lawyers and the witnesses in co-construction of the story within the testimony, as well as the constraining nature of courtroom context. Further the results of theoretical analysis of genre definition were mapped on major narrative dimensions (tellership, tellability, linearity, embeddedness and moral stance) in institutional context of courtroom hearings. The findings of this research showed that witness narratives in testimonies are fragmented, characterized by nonlinear chronology and nonlinear causal logic of events presentation; even though the witnesses are restricted in what and how they tell, the stories they tell are highly relevant for the fact detection in court; testimonies are of dialogical nature, with the lawyers inevitably becoming co-tellers of the witness story; testimonies are embedded into power-asymmetrical ‘question-answer’ pattern of examination; the identity of the witness (and their credibility) is constructed and deconstructed throughout the testimony.
COLOUR TERMS IN INORGANIC CHEMISTRY: A CORPUS STUDY
Authors: Stanulewicz Danuta , Radomyski Konrad 
Published: November 2022

Colour is a common physical phenomenon involving selective absorption, reflection or transmission of certain wavelengths of light. It is one of the fundamental properties of chemical compounds, which is particularly evident in the field of inorganic chemistry. The aim of this paper is to present colour terms used by scientists in the field of inorganic chemistry. We concentrate both on basic and non-basic colour terms – as understood by Berlin and Kay (1969). The research material is extracted from a corpus compiled with AntConc, consisting of abstracts published in Inorganic Chimica Acta, Inorganic Chemistry Communications, Journal of Inorganic Biochemistry and ten other chemical journals. The size of the corpus is 1,626,380 words. The most frequent basic colour terms found in the abstracts are blue (370 occurrences), green (302) and red (222), whereas the non-basic terms include, among others, violet (46) and cyan (4). In this paper, we investigate the uses of these and other colour words, focusing mainly on their occurrence in names of chemical compounds and other terms as well as in descriptions.
Identification and Management of Parasitic Nematodes Associated with Mulberry in Mansehra, KP, Pakistan
Authors: Nadia Saeed  , Raqeebullah  , Qasim Saeed  , Khalid Usman  , Fahim Haider Jamali  , Muhammad Sabir  , Muhammad Aslam Khan  , Iftikhar Hussain  
Published: November 2022

Parasitic nematodes are destructive parasites of crop plants and cause enormous damage to them. The earliest signs of nematodes attack are the inactiveness of growth as infestation of nematodes is a slow process. The survey was held to evaluate the percentage of the plant-parasitic nematodes that related to mulberry in various localities in the District Mansehra. For this purpose Mansehra, Balakot and Oghi were selected. From these different areas soil samples were collected and processed by using Baermann funnel technique to examine and calculate the percentage of saprophytic and parasitic nematode populations. From the results it had shown that samples from Mansehra and Balakot had more parasitic nematodes than saprophytic while samples from Oghi were found saprophytic. Tehsil Mansehra showed 65% whereas tehsil Balakot showed 35% population of parasitic nematodes. From Mansehra and Balakot, Helicotylenchus dihystera was found in profusion. For the management of parasitic nematodes inorganic amendment (Carbofuran) and organic amendments (Poultry manure) were used in 250 gram/tree and 8kg/ tree respectively. Samples and subsamples from both treated and untreated trees showed that Carbofuran exterminated the nematode population entirely whereas the population of parasitic nematodes decreased by the implementation of Poultry manure to a notable point. Histograms analysis and ANOVA was done. ANOVA showed that p value for both Carbofuran and Poultry manure impact in Mansehra and Balakot was 0.0001 and therefore was found significant. Thus both were found effective however Poultry manure is more eco-friendly in nature.
Screening and Prevalence Study of Diabetic Retinopathy in Multan, District of Pakistan: A Cross Sectional Study
Authors: Qurratul-ain Leghari  , Faiza Akhtar  , Shahzad Aslam  , Kiran Rafique  , Saba Majeed  , Saira Shanaz  , Mehwish Wajdi  , Arfa Akram  , Sharmeen Bawani  
Published: November 2022

The present study was designed to assess the Screening and Prevalence study of Diabetic Retinopathy in Multan, district of Pakistan.
Materials & methods: In 2020, a medical camp has been placed and a retrospect study has been conducted in Muzaffargarh, Multan District, Punjab. 1150 people of age group between 45-65 years were examined, under the supervision of a pharmacist team.
Results: Noting the BMI, blood sugar test was performed; patients having blood sugar level above the limit (125mg/dl) were considered as diabetic and further examined for diabetic retinopathy by performing fundoscopy. It was observed that around 45% of individuals were suffering from Diabetes highlighting almost 60% by male population. Upon further investigation, it was noticed that male population suffers more with diabetic retinopathy (71.77%) as compared to females i.e., 56.03%. Considering obesity and smoking as a risk factor, around 74% male population lied under extreme obese category whereas smoking was found more common in female population 80.55%.
Conclusion: Diabetes affects many organs along with liver and kidneys. In n=1150 people, n=522 persons were tested positive for diabetes. Among 522 individuals’ male population was more affected with diabetic retinopathy. Smoking and obesity were the risk factors that are associated with disease.
Anti-Obesity Effect of Carom Seeds (Trachyspermum Ammi) Tea on Bmi and Lipid Profile Leading to Cardiovascular Diseases
Authors: Zubdah Yaqoob  , Muhammad Iqbal  , Asma Nouren  , Shaukat Sohail  , Mansoor Ali  , Taiba Fazal  , Misbah Rustam  , Zahoor Ahmed  , Nadia Saeed  , Qasim Saeed  
Published: November 2022

Introduction: Obesity refers to the deposition of fat ratio in the fat tissues of muscles in which the BMI raised (obesity and hyperlipidemia) that may have a negative impact on health. Herbs from ancient times till today have been utilized as a solution for some infections and issues. Objectives: The purpose of this research was to evaluate the defensive impact of Carom seed (Trachyspermum ammi) against obesity and hyperlipidemia. Materials & Methods: Carom seed was acquired from the Faisalabad and was washed to expel the soil, dust, and outside materials clung to the test surface. The crude material was dried by utilizing an air forced draft oven. After planning, it was stuffed in water/airproof plastic containers and put away at 5 ± 1 °C until further analysis. Moreover, the blood samples were collected on 0-day, 15-day, 30-day, and 60-day by taking 15ml venous blood after a 12-hour night of fasting. Serum samples were separated by centrifugation and stored at -70?c until analysis. Low-density lipoprotein and high-density lipoprotein cholesterol were measured enzymatically. Concentrations of triglycerides and total cholesterol were measured by Peridochrom Triglyceride Kits. Sixteen subjects, separated into four groups were given carom seeds in the form of tea i.e. G0 (Control), G1 (500mg), G2 (1 mg) and G3 (1.5 mg) individually. This was an eight-week trial and all the parameters e.g. Body Mass Index, High-Density Lipid, Low-Density Lipid, Tri-Glycerides, and Total Cholesterol were measured at 0 days, 15 days, 30 days, and 60 days respectively. The yield data of carom seed tea for anti-obesity and anti-hyper-lipidemic effects obtained for each treatment were subjected to a paired t-test by using SPSS. Results: The significant change has been observed between the groups with the relevance of treatments given. G0 showed no significant changes among all the groups while G2 and G3 reported considerable changes because of the dosage concentrations of carom seed tea i.e. 1g and 1.5g respectively (p<0.05).
Nutritional Profile of Different Rangelands Plant Species Grazed by Small and Large Ruminants in Balochistan
Authors: Reki Muhammad Yaseen , Abro Rani , Marghazani Illahi , Mughal Gulfam Ali , Sasoli Muhammad Afzal , Khaskhali Abdul kareem , Ahmed Shafiq , Esot Ghulam Farooq , Qadir Ayaz , Babar Hilal Ahmad Abbasi  , Tahir Hameed  
Published: November 2022

This study conducted to know the nutrients composition of different rangelands plant species (grasses, herbs, shrubs, and trees) grazed by small and large ruminants in Lasbela region, Balochistan. Fifteen different rangeland plant species were collected from three different areas of Lasbela region and botanically identified by panel as Salvadora persica L, Prospis Juliflora, Suaeda fruticosa, Conolulus glomeratus Choisyin, Calotropis Procera, Prospis Juliflora, Cressa Cretica L, Sehoenus Nigricans L, Datura Alba Solanaceae, Taverniera Spartea, Abutilon Muticuin, Heliotropium Curassavicum, Prosopis Cineraria, Ziziphus Mauritiana and Cynodon Dactylon. The dry matter (DM), crude protein (CP), ether extract (EE), ash, neutral detergent fiber (NDF), acid detergent fiber (ADF), cellulose, cell soluble (SC) and organic matter (OM) contents were determined according to the standard procedures. Data collected on nutritive profile of all collected rangeland plant species were statistically analyzed and significance difference was measured among collected rangeland plant species.
Poor Apgar Score of Neonates Born to the Females Presenting with Pregnancy Induced Hypertension for Delivery
Authors: Mehnaz Gondal  , Bushra Sayyed  , Rabia Wajid  , Ayesha Inayat  , Robina Kosar  , Sofia Tariq  
Published: November 2022

Background: Pregnancy induced hypertension (PIH) is defined as BP ? 140/90 mmHg, taken after a period of rest on two occasions or ?160/110 mmHg on one occasion in a previously normotensive woman. One of the most important aspects is the outcome of pregnancy with PIH. Poor Apgar score is commonly observed in females with PIH. So we conducted this study to find the extent of problem in local population. Objective: To assess the frequency of poor Apgar score of neonates born to the females presenting with pregnancy induced hypertension at term (37-41 weeks) for delivery.
Study Design: Descriptive case series. Setting: Unit 4, Department of Gynecology & Obstetrics, Sir Ganga Ram Hospital, Lahore. Duration of Study: 6 months after approval of synopsis i.e. from: 09-11-2021 to 10-05-2022 Patients. Methods: 125 pregnant females with PIH were followed till delivery by researcher herself. After delivery, neonate was assessed for Apgar score at 1 & 5 minutes, if <7, then it was labeled as poor Apgar score. All this information was recorded on proforma. Statistical analysis was done using SPSS version 20.
Results: The mean age of patients was 30.50±6.22years. The mean gestational age was 39.78±1.66weeks. The mean BMI was 26.99±5.13kg/m2. There were n=59 (47.2%) male neonates while n=66 (52.8%) female neonates. The mean Apgar score at 1minute was 7.29±1.36 while at 5minutes was 7.70±1.29. Poor Apgar score was noted in n=19 (15.2%) neonates while n=106 (84.8%) neonates had normal Apgar score. Conclusion: The frequency of poor Apgar score (at 1 minute and continuously <7 at 5 minutes) was 15.2% in neonates born to females with PIH. The neonates with poor Apgar Score were admitted to NICU and were managed according to standard hospital protocol