bluuebunny/crossref_metadata_2025_split huggingface dataset:
Medical Staff Social Practice and Attitude towards People with Mental Disorders
Authors: Oksana Stadnik , Bohdan Sliushchinskiy , Nataliia Varha , Olena Khodus , Nataliia Polovaia 
Published: April 2022

Background: Considering the social vulnerability of the people with mental disorders and a certain dualism of treatment practice within this social category of people and beginning from socializing process to isolation in Ukrainian society, it becomes relevant to prevent the formation of antisocial and stigmatizing consequences toward the patients with mental disorders in society.
Objective: The article's aim involves the social practice of studying and attitude toward patients with mental disorders. They are based on the results of sociological questionnaires.
Methods: The questionnaire is based on psychiatrists and psychiatric hospitals’ medical staff surveys. It covers 505 medical workers of the Regional Clinical Psychiatric Hospital in the Zaporizskiy region of Ukraine.
Results: The result points to the domination of neutral attitude toward the mentally disabled people among the respondents-experts (medical and junior medical staff including), which in turn causes several negative consequences as follows: lack of understanding of treatment differences concerning the mentally healthy and mentally ill; a latent reluctance for changing the social treatment practice towards the mentally ill in a more humane way; distancing from the mentally ill; a change of verbally-behavioral practice to antisocial, hostile ones. etc.
Conclusions: Despite the globalization of the modern world, the local composition of verbal-behavioral social practice toward people with mental disorders is influenced by socio-cultural, economic, and political determinants.
Cumulative Rehearsal and Auditory Verbal Memory of Persons with Down Syndrome
Authors: Dada Oluseyi Akintunde , Okpara Anulika Chinyere , Adeleke Owoade Philip , Okon Maureen Okang , Merimekwu Anne , Anagbogbu Effa German , Petters Janet , Edu Grace Onya , Eno Asuquo , Akah Levi Udochukwu , Olufu Martin Afen 
Published: April 2022

One of the characteristics of persons with Down syndrome is poor memory, especially the Auditory-Verbal Memory (AVM). Lack of verbal memory among persons with Down syndrome is one major factor that inhibits learning. This is why the effort towards enhancing AVM of persons with Down syndrome is evolving. This study, therefore, investigated the efficacy of cumulative rehearsal on auditory verbal memory of persons with Down syndrome with speech production and gender as moderator variables.
A 2 x 2 x 2 factorial matrix of pretest-posttest control group experimental design was used in the study. A sample of thirty participants was drawn from a population of 44 persons with Down syndrome and randomly assigned to control and experimental groups in two special schools; National Orthopaedic Special School, Igbobi, and Modupe Cole Memorial Childcare and Treatment Home/School, Akoka. Data was collected using a validated self-developed instrument, Auditory Verbal Memory Assessment Scale (AVMAS) (r-0.86). Two hypotheses were tested using ANCOVA.
Findings from the study revealed that: cumulative rehearsal therapy significantly impacted the auditory-verbal memory of persons with Down syndrome, with significant improvement observed. There was no significant interaction effect of speech level and gender with the therapy.
It was thus concluded that cumulative rehearsal therapy is effective in enhancing auditory-verbal memory and so recommended for the improvement of AVM of persons with Down syndrome.
Factores psicosociales asociados a la credibilidad del testimonio en Abuso Sexual Infantil
Authors: Cabezas-García María , De la Peña Fernández María Elena , Andreu Rodríguez José Manuel 
Published: April 2022

Background: Credibility assessment in Child Sexual Abuse (CSA) poses a major challenge for forensic psychology. The lack of evidence supporting the determination of the real occurrence of the abuse requires additional approaches to assess credibility. The purpose of this research is to explore the existence of psychosocial factors associated with testimony credibility in CSA. Method: Ninety-nine CSA cases characterized as Credible (C) or Not Credible (NC) were evaluated. The age range of the group spanned 4 to 17 years (M = 11.31, SD = 3.92) with 87 (85.9%) cases corresponding to females. Group C incuded 68 cases and NC group the remaining 31. The relationship between the expert opinion (C/NC) and psychosocial factors was evaluated using contingency tables and chi-square analysis. Results: Significant differences in variables such as the presence of sexual and emotional imbalances, dysfunctional family dynamics, parent litigation, or legal actions against a relative were found. Conclusions: Certain variables were commonly present in the NC group, such as symptoms of a sexual nature, dysfunctional familiar dynamics, divorced parents, presence of litigation between parents, or legal actions against the biological father.

Antecedentes: La credibilidad del testimonio en Abuso Sexual Infantil (ASI) es un reto para la psicología forense por falta de otras pruebas que ayuden a determinar judicialmente la ocurrencia del abuso. Existen diferentes enfoques para valorar la credibilidad del testimonio, aunque la mayoría presenta limitaciones. El propósito de esta investigación es explorar la existencia de indicadores psicosociales asociados a la credibilidad del testimonio en ASI para complementar las valoraciones periciales. Método: La muestra se compone de 99 casos de ASI evaluados como Creíbles (C) o No Creíbles (NC) con una edad que osciló entre los 4-17 años (M = 11.31, DT = 3.92) y de los que 87 (85.9%) fueron niñas. El grupo C contenía 68 casos y el NC 31. Se examinó la relación entre el dictamen pericial (C/NC) y factores psicosociales mediante tablas de contingencia y análisis de chi-cuadrado. Resultados: Encontramos diferencias significativas en variables como la presencia de desajustes sexuales y emocionales, una dinámica familiar disfuncional, el litigio entre progenitores o la denuncia contra un familiar. Conclusiones: Se identifican variables presentes de forma habitual en el grupo NC como la presencia de sintomatología de índole sexual, dinámicas disfuncionales, padres divorciados, presencia de litigio entre los progenitores o la denuncia contra el padre biológico.
Aplicación del protocolo unificado para el tratamiento transdiagnóstico de los trastornos emocionales en pacientes post-cirugía bariátrica: estudio de efectividad y viabilidad en formato grupal
Authors: Ferreres-Galán Vanesa , Quilez-Orden Alba B. , Osma Jorge 
Published: April 2022

Obesity is a serious health problem with global implications. Bariatric surgery (BS) is the most used and effective treatment, but there are patients who do not lose a substantial amount of weight, a fact that has been related with the presence of emotional eating, anxiety and depression symptoms. The aim of this study is to analyze the effectiveness and feasibility of an emotion regulation-based intervention called Unified Protocol (UP), applied in group format to 6 post-BS patients presenting emotional disorders/symptoms. Results at post-treatment shown high attendance rates and satisfaction with the UP scores and significant improvements on neuroticism, eating disorders symptoms and emotional eating. At 6-month follow-up we found significant reductions on anxiety symptoms, neuroticism, maladjustment and dysregulation (d = 0.83-1.46) and the body mass index remained stable over time. These preliminary results are encouraging about the effectiveness and feasibility of the UP to treat emotional dysregulation in patients after BS.
La obesidad es un grave problema de salud con implicaciones globales. La cirugía bariátrica (CB) es el tratamiento más utilizado y eficaz, pero hay pacientes que no pierden una cantidad sustancial de peso, hecho que se ha relacionado con la presencia de síntomas de alimentación emocional, ansiedad y depresión. El objetivo de este estudio es analizar la viabilidad y efectividad de una intervención basada en la regulación de las emociones denominada Protocolo Unificado (PU), aplicada en formato grupal a 6 pacientes post-CB que presentan trastornos/síntomas emocionales. Los resultados tras el tratamiento mostraron altas tasas de asistencia y satisfacción con el PU, y mejorías estadísticamente significativas para el neuroticismo, los síntomas de los trastornos alimentarios y la alimentación emocional. En el seguimiento a los 6 meses, se muestran reducciones significativas en los síntomas de ansiedad, neuroticismo, inadaptación y disregulación (d = 0.83-1.46) y el índice de masa corporal se mantuvo estable a lo largo del tiempo. Estos resultados preliminares son esperanzadores sobre la viabilidad y efectividad del PU para tratar la disregulación emocional en pacientes después de la CB.
Objective assessment of goal orientation, time management and learning outcomes
Authors: Romero Miriam , Juola James , Casadevante Cristina , Hernández José Manuel 
Published: April 2022

Behaviors directed to achieving goals and managing tasks in a set period of time play important roles when people engage in learning activities. These behaviors, labeled goal orientation and time management, have been widely studied as part of self-regulated learning models. Previous works have traditionally employed self-reports to study these variables. However, these subjective methodologies suffer from limitations, and some researchers highlight the advantages of using objective measures. In the present work, we employ objective tests to study goal orientation, time management and their relation to learning outcomes. We propose a model and employ structural equation modeling to examine the hypothesized relations. The results provided a good fit to the data. Goal orientation (mastery) has a direct effect on time management, and both variables have direct effects on scores in a learning task. Time management also has a direct effect on academic performance. Theoretical and practical implications are discussed.
Las conductas dirigidas a lograr metas y a gestionar tareas en un periodo de tiempo determinado desempeñan un papel importante cuando las personas realizan actividades de aprendizaje. Estos comportamientos, denominados como orientación a metas y gestión del tiempo, han sido ampliamente estudiados desde los modelos de aprendizaje autorregulado. Estudios previos han empleado tradicionalmente auto-informes para estudiar estas variables. Sin embargo, esta metodología subjetiva presenta limitaciones, por lo que algunos autores han enfatizado las ventajas del empleo de medidas objetivas. En este trabajo, empleamos test objetivos para evaluar la orientación a metas, la gestión del tiempo y estudiar su relación con resultados de aprendizaje. Se emplea un modelo de ecuaciones estructurales para examinar las relaciones. Los resultados muestran un buen ajuste del modelo a los datos. La orientación al aprendizaje muestra un efecto directo sobre la gestión del tiempo y ambas variables muestran un efecto directo sobre una tarea de aprendizaje. La gestión del tiempo mostró un efecto directo sobre el rendimiento académico. Se discuten las implicaciones teóricas y prácticas.
Estimation of Import Demand Elasticities, In the BPCG Model and the Import Demand Function (The Case Study of Iran)
Authors: Safari Saeede 
Published: April 2022

In this study, the demand elasticities of import are estimated, with two approaches, the balance of payments constrained growth (BPCG) or Thirlwall model and the import demand function, by using data in Iran during the period 1980 to 2018 and ARDL method.
According to BPCG model, economic growth is equal to the ratio of export growth to income elasticity of import demand, so it is related to the growth of exports and income elasticity of import demand in the long run.
Based on this model, if national income increase and the income elasticity of import demand is high, the imports increase, the effect of export growth and consequently economic growth decreases.
The results showed that in the long run, the income elasticity of import demand in BPCG model isequal to 0.04 and based on the import demand function is 0.34 and the relative price elasticity of import demand (the ratio of import price to domestic price) is -0.52. Therefore, imports in Iran have been more affected by price than income effects.
Due to the smaller amount of income elasticity of import demand in both models and based on the BPCG model, the greater income elasticity of import demand, reduces the effect of export growth coefficient, it can be concluded that the magnitude of this elasticity has not been a constraint to Iran's economic growth. Given the significant impact of prices on imports, economic planners should focus on increasing the competitiveness of domestic products.
Heart Failure Associated with Rheumatoid Arthritis
Authors: Akrim M. , Jourani S. , Chachi A. , Hattaoui M. EL. 
Published: April 2022

Rheumatoid arthritis (RA) is a chronic inflammatory disease of the joints. Extra-articular features are very common. We report a case of RA first diagnosed after an episode of congestive heart failure (CHF) and the evolution of left ventricular function after conventional treatment of CHF and immunosuppressive drugs. The patient, a 52-year-old man, with history of epilepsy and a stroke 6 years before, presented to the emergency department with increasing dyspnea. He had polyarthralgia 2 months before. The lower extremities had mild pitting edema. The musculoskeletal examination revealed synovial thickening of the metacarpophalangeal and proximal interphalangeal
joints, but there was no joint tenderness. The patient’s alanine aminotransferase, troponin levels and CRP were slightly elevated. His renal function was preserved. The electrocardiogram (EKG) was normal. An echocardiogram performed in showed a global hypokinetic dilated cardiomyopathy with an ejection fraction of 15–20%, with apical thrombus. The patient was diagnosed with exacerbation
of congestive heart failure (CHF) and was treated with intravenous diuretics. This led to symptomatic improvement. He got a conventional heart failure treatment with vit K antagonists. Coronarography was normal. Viral serologies were negative. The martial, phosphocalcic and thyroid markers were normal. However, the immunologic tests showed positive rheumatoid factor and anti-CCP. The diagnosis of dilated cardiomyopathy due to rheumatoid arthritis was retained. The patient was treated by corticosteroids and immunosuppressive agents. Patient was seen during routine follow-up after 6 months. Interestingly, echocardiographic findings were totally normal with left ventricular ejection fraction >50% and normal LV size.
Effect of Invasive Weed Biochar Mixed with Inorganic Fertilizer on Soil Physical and Chemical Properties in Semi-arid Region of India
Authors: Choudhary Payal , Prasad Mahendra , Choudhary Mukesh , Kumar Awanish , Mahawer Sonu Kumar , Srinivasan R. , Kumar Sunil 
Published: April 2022

The application of different forms of organic material is a traditional strategy used to sustain soil fertility by replenishing soil organic matter (SOM) and enhancing nutrient profile for crops. This study focuses on the comparative efficacy of biochar prepared from locally available invasive weed biomass (Parthenium hysterophorus L. and Lantana camara L.) with or without inorganic fertilization on soil properties and nutrient availability in post harvested soils. Results revealed that soil bulk density (BD) was significantly decreased with application of biochar @ 5 t ha-1 and 10 t ha-1 along with 75% RDF (Recommended dose of fertilizers) as compared to control while water holding capacity (WHC) significantly increased in the range of 18.40-32.78% as compared to RDF by the application of Parthenium hysterophorus L. and Lantana camara L. biochar @ 2.5 t ha-1, 5.0 t ha-1 and 10.0 t ha-1 along with 75% RDF. It was also observed that Parthenium hysterophorus L. and Lantana camara L. biochar along with 75% RDF addition to soil increased SOC (5.17 g kg-1 to 7.99 g kg-1) and cation exchange capacity (CEC) by 3.36-37.14% as compared with control, depending on the quantity of biochar application. Similar trends were also reported in case of available macro and micro nutrients in the post harvest soil. Therefore, application of invasive weed biochar with inorganic fertilization is considered as promising strategy for improve physical and chemical properties of soils and soil health in semi-arid ecosystem.
Bioanalytical Method Development and Validation for the Estimation of Saxagliptin in Marketed Tablet Formulation
Authors: Jain Prabhat Kumar , Tyagi C. K. , Dayaramani Richa 
Published: April 2022

The concepts, importance and application of bioanalytical method development have been discussed for a long time and validation of bioanalytical methods is widely accepted as pivotal before they are taken into routine use. Now it is widely accepted that bioanalysis is an integral part of the clinical diagnosis, biomarker discovery, pharmacokinetic/ pharmacodynamic characterization of a novel chemical entity from the time of its discovery and during various stages of drug development, leading to its market authorization. Bioanalytical methods, based on a variety of physico-chemical and biological techniques such as chromatography, immunoassay and mass spectrometry, must be validated prior to and during use to give confidence in the results generated. This study describes the development of an innovative, rapid, precise, selective and sensitive reverse phase high-performance liquid chromatography method for the quantitative determination of Saxagliptin (SAXA) in human plasma and pharmaceutical dosage form. Extraction of drug from plasma was done by employing optimized liquid-liquid extraction procedure. The sample was analyzed using methanol: acetonitrile in the ratio of 50:50v/v as mobile phase. Chromatographic separation was achieved on Thermo C18 analytical column (250mm×4.6mm i.d., 5.0μm) as stationary phase using isocratic elution (at a flow rate of 1 ml/min). The peak was detected using UV-PDA detector set at 230 nm and the total time for a chromatographic separation was 20 min. The calibration curve obtained was linear (r2 = 0.999) over the concentration range of 5-25μg/ml for SAXA. Method was validated for precision, robustness and recovery.
Awareness and Knowledge of Coronary Heart Disease among the General Population: A Systematic Review
Authors: Yogyanti Kurnia , Kristina Susi Ari , Wiedyaningsih Chairun 
Published: April 2022

Introduction: Coronary heart disease (CHD) is one of the cardiovascular diseases that become the leading cause of death (LCOD) in the United States. Knowledge gaps in CHD and its risk factors are significant obstacles to effective prevention and treatment. People's awareness of CHD and their knowledge of its risk factors could provide crucial information for behavior change in the prevention of CHD. Therefore, the purpose of this review was to examine some of the literature on the knowledge and awareness of CHD in the general population.
Study Design: Systematic Review.
Methodology: Two databases were searched for publications between 2011 and 2021. All studies that were published in English and had components of awareness and knowledge related to CHD were included. A total of 1082 titles and abstracts were screened, 55 full-text articles were assessed and 15 were included for review.
Results: This review used data from a total of 4907 respondents and the results were varied. Studies that were conducted in the same countries might have different results. Men and participants with a college education have better knowledge than their counterparts. Meanwhile, another study shows that the elderly have poor knowledge about CHD. Several studies conducted among university employees showed that the majority of participants had poor knowledge of risk factors, while another study showed good knowledge.
Conclusion: Our review study showed that most of the study participants had low awareness of CHD and knowledge of its risk factors. Family history of CHD, risk factor profile, and some sociodemographic factors have been reported to be associated with the awareness and knowledge of CHD. Providing health information by healthcare professionals can be the right way to increase people’s awareness and knowledge in order to prevent CHD in the future.
Etravirine Lipid Nanoparticles: Development and Validation Using Specific RP-HPLC Technique
Authors: Banode Kunal Badrinarayan , Belgamwar Veena Shailendra , Mishra Suchitra Shitla 
Published: April 2022

Introduction: A common, exact & economical reverse phase-high performance liquid chromatographic approach for coinciding measurement of anti-retroviral medicine, Etravirine in the formulation of nanoparticle has been devised. This approach is a revolutionary analytical methodology for detecting substance at the same time.
Methods: Validation & optimization chromatographic conditions were completed as per the guidelines of ICH. The disconnection was done on a column measuring (150mm x 4.6mm, 5μ) using the mobile phase consisted of acetonitrile and 10mM ammonium acetate buffer in the ratio of 90:10 v/v of pH 2.7 as the mobile phase in the ratio 85:15 at a flow rate of 1ml/min for a short run time of 13 minutes. The wavelength was 310nm & the column temperature was kept at 26°C.
Results: The devised technique was linear at 10, 20, 30, 40, as well as 50 g/ml, with a regression coefficient of 0.999 for each of these concentrations. For etravirine, the LOD readings were 0.514 g/ml, whereas the LOQ readings were 1.713 g/ml. Etravirine was shown to have a recovery rate of 98.8%.
Conclusion: The approach was, precise, accurate & rapid with excellent inter- & intra-day accuracy. The approach was also useful for characterization & coinciding measurement of medicines in formulation of nanoparticles.
Towards a Sustainable China-Africa Forest Products Trade; an Assessment of Environmental Implications for FOCAC Members
Authors: Bingpu Chen , Yeboah Frederick Kwame , Coffie Cephas Paa Kwasi , Abdullahi Bello Nasiru 
Published: April 2022

Forest products have become an integral component of China-Africa trade engagement. However, with increasingly global climate change warnings and the need to turn down the heat below the pre-industrial level, understanding the trade-off from forest trade in relation to CO2 emissions is paramount in shaping forest product trade sustainability in the long run. This study, therefore, tests the haven and halo hypothesis based on the FMOL technique by analyzing China-FOCAC forest products trade engagements. A balanced panel data of 20 FOCAC members were selected based on availability and consistency from 2000-2014. The variables; forest products trade (exports value), GDP per capita, FDI inflow, institutional quality, energy use and carbon emissions were gleaned from the world bank and the United Nations database. The descriptive statistics results reveal a disparity in economic growth, FDI inflow and value of forest products exports among FOCAC members. Per the FMOL estimation results, the China-FOCAC forest products trade has an insignificant impact on the level of carbon emissions in the selected countries which contributes to the ongoing debate on whether Africa is a pollution haven for China. Nevertheless, Per capita GDP and energy use are significant drivers of emissions whereas FDI’s and the quality of institutions have shown high potential for transforming the quality of the environment in the selected countries. These results are paramount in shaping existing and future forest trade agreements.