bluuebunny/crossref_metadata_2025_split huggingface dataset:
Global expressivism and alethic pluralism
Authors: Price Huw 
Published: September 2022

AbstractThis paper discusses the relation between Crispin Wright’s alethic pluralism and my global expressivism. I argue that on many topics Wright’s own view counts as expressivism in my sense, but that truth itself is a striking exception. Unlike me, Wright never seems to countenance an expressivist account of truth, though the materials needed are available to him in his approaches to other topics.
Circulating redox status in sheep naturally infected with Trichophyton verrucosum
Authors: Saleh Mostafa A. , Rateb M. H. , Abd-Allah Elham A. , Mohamed Ghada A. E. 
Published: September 2022

Abstract
Trichophyton verrucosum is a zoophilic dermatophyte that causes skin inflammation. The present study aimed to evaluate the redox status in the blood of sheep clinically infected with T. verrucosum. According to clinical and mycological investigations, 48 juvenile male Balady sheep were selected in their natural habitat and divided into four groups depending on the lesion size: mild (MID), moderate (MOD), severe (SEV) T. verrucosum infection, and healthy control groups. Compared to the controls, plasma superoxide anion increased (P < 0.05) in both MOD and SEV but total peroxides (TPx) gradually increased (P < 0.05) in MID followed by MOD and SEV. Superoxide dismutase and total antioxidant capacity (TAC) were higher (P < 0.05) in MID and lower (P < 0.05) in MOD and SEV than in controls, but SEV showed lower TAC than MOD. Malondialdehyde (MDA, a lipid peroxide marker) increased (P < 0.05) in SEV than in controls, but protein carbonyl (PC, a protein peroxidation marker) was augmented (P < 0.05) as lesions progressed from mild to severe. The oxidative stress index (TPx/TAC ratio) progressively increased (P < 0.05) in MOD and SEV. The correlation of PC was positive with TPx and negative with TAC (P < 0.01). In conclusion, sheep infection with T. verrucosum is characterized by increased TPx and decreased TAC in plasma depending on the lesion area. The redox status is shifted towards the oxidizing state, particularly in MOD and SEV cases. This results in a condition of OS, which may contribute to the pathogenesis of the disease.
Integrating self-regulated learning and individual differences in the prediction of university academic achievement across a three-year-long degree
Authors: Pérez-González Juan-Carlos , Filella Gemma , Soldevila Anna , Faiad Yasmine , Sanchez-Ruiz Maria-Jose 
Published: September 2022

AbstractThe study investigated the joint contribution of the self-regulated learning (SRL) and individual differences approaches to the prediction of university students’ grade point average (GPA) obtained at three separate time points throughout their degree (3 years). We assessed cognitive (i.e., previous academic performance, cognitive ability, and cognitive SRL strategies) and non-cognitive variables (i.e., personality, trait emotional intelligence, motivation, and non-cognitive SRL strategies) in a sample of Spanish undergraduates. Results showed that GPA correlated with previous academic performance (i.e., combination of high school’s GPA and college admission test score), academic self-efficacy, academic engagement, SRL strategies, and conscientiousness. Hierarchical regression analyses indicated that non-cognitive factors (i.e., academic engagement, academic self-efficacy, regulation of behavior and context, and conscientiousness) alone explained 17–25% of the variance in GPA across three years, and previous academic performance accounted up to an additional 25% of the variance, jointly reaching an explained variance of up to 50% in GPA. Specifically, academic engagement and regulation of behavior and context demonstrated incremental validity over and above cognitive predictors such as previous academic performance, inductive reasoning and regulation of cognition and metacognition. The role of intelligence, whether cognitive or emotional, was not as obvious as a predictor. Two nested structural equation models explained about 27–29% of the variance in a latent GPA factor exclusively from a proxy of a global variable of non-cognitive factors as a latent predictor, which is a novel and promising proof of its robust criterion validity. Implications and recommendations for future studies are discussed.
Electromagnetic tool for the endoscopic creation of colon anastomoses—development and feasibility assessment of a novel anastomosis compression implant approach
Authors: Steger Jana , Zimmermann Anne , Wittenberg Thomas , Mela Petra , Wilhelm Dirk 
Published: September 2022

Abstract
Background
Colorectal anastomoses are among the most commonly performed interventions in abdominal surgery, while associated patient trauma is still high. Most recent trends of endoscopic anastomosis devices integrate magnetic components to overcome the challenges of minimally invasive surgery. However, the mutual attraction between magnetic implant halves may increase the risk of inadvertently pinching healthy structures. Thus, we present a novel anastomosis device to improve system controllability and flexibility.

Methods
A magnetic implant and an applicator with electromagnetic control units were developed. The interaction of magnetic implants with the electromagnets bears particular challenges with respect to the force-related dimensioning. Here, attraction forces must be overcome by the electromagnet actuation to detach the implant, while the attraction force between the implant halves must be sufficient to ensure a stable connection. Thus, respective forces were measured and the detachment process was reproducibly investigated. Patient hazards, associated with resistance-related heating of the coils were investigated.

Results
Anastomosis formation was reproducibly successful for an implant, with an attraction force of 1.53 $$\pm 0.3 N$$

±
0.3
N

, resulting in a compression pressure of $$0.0048 \frac{N}{{\mathrm{mm}}^{2}}$$

0.0048

N

mm

2

. The implant was reproducibly detachable from the applicator at the anastomosis site. Coils heated up to a maximum temperature of $${T}_{\mathrm{max}}=41.6 \pm 0.1^\circ \mathrm{C}$$

T
max

=
41.6
±
0
.

1
∘

C

. Furthermore, we were able to establish a neat reconnection of intestinal bowel endings using our implant.

Discussion
As we achieved nearly equal compression forces with our implant as other magnetic anastomosis systems did (Magnamosis™: 1.48 N), we concluded that our approach provides sufficient holding strength to counteract the forces acting immediately postoperatively, which would eventually lead to an undesired slipping of the implant halves during the healing phase. Based on heat transfer investigations, preventive design specifications were derived, revealing that the wall thickness of a polymeric isolation is determined rather by stability considerations, than by heat shielding requirements.
Narrative Review of the Role of Patient-Reported Outcomes and Inhaler Handling Errors in the Control of Asthma and COPD
Authors: De Simón Gutiérrez Raúl , Castro Raúl Piedra 
Published: September 2022

Abstract
Purpose of Review
Asthma and chronic obstructive pulmonary disease (COPD) are chronic respiratory diseases that remain uncontrolled in many patients, despite the wide range of therapeutic options available. This review analyzes the available clinical evidence on 3 budesonide/formoterol DPI devices, Spiromax®, Turbuhaler®, and Easyhaler®, in terms of patient-reported outcomes (PROs), inhaler errors, and asthma and COPD control.

Recent Findings
The effectiveness of dry powder inhalers (DPI) depends largely on the device and the patient’s inhaler technique. Equally important are the patient’s perception of the inhaler and adherence. Given the high burden of these diseases, it is important that efforts be made to select the best DPI for each patient and to analyze the impact of these variables to help improve the health and quality of life of our patients.

Summary
This review provides a comprehensive overview of the present knowledge about PROs, inhaler handling errors, and asthma and COPD control achieved by Spiromax®, Turbuhaler®, and Easyhaler®.
PCSK9 Inhibitor Wars: How Does Inclisiran Fit in with Current Monoclonal Antibody Inhibitor Therapy? Considerations for Patient Selection
Authors: Arnold Natalie , Koenig Wolfgang 
Published: September 2022

Abstract
Purpose of Review
Treatment of dyslipidemia represents one of the most crucial strategies to reduce risk of atherosclerotic cardiovascular (CV) disease (ASCVD). In this review, we critically summarize our knowledge on emerging cholesterol-lowering therapy, targeting PCSK9, paying particular attention on treatment allocation of two drug groups, currently available for clinical use, namely, anti-PCSK9 monoclonal antibodies (mAbs) and inclisiran, a first-in-class small interfering RNA against PCSK9.

Recent Findings
Although both drug classes show a pronounced, but fairly similar reduction in LDL-cholesterol, their long-term safety is still unknown. Compared to mAbs, inclisiran has a more favorable dosing regimen with biannual application that might improve therapeutic adherence significantly. However, a CV outcome trial (CVOT) for inclisiran is still missing.

Summary
If inclisiran will be safe and effective in ongoing/future CVOTs, it has a huge potential to overcome medication non-compliance, thereby providing a powerful therapeutic option to decrease the burden of ASCVD.
Pathways Controlling Formation and Maintenance of the Osteocyte Dendrite Network
Authors: Wang Jialiang S. , Wein Marc N. 
Published: September 2022

AbstractPurpose of ReviewThe purpose of this review is to discuss the molecular mechanisms involved in osteocyte dendrite formation, summarize the similarities between osteocytic and neuronal projections, and highlight the importance of osteocyte dendrite maintenance in human skeletal disease.Recent FindingsIt is suggested that there is a causal relationship between the loss of osteocyte dendrites and the increased osteocyte apoptosis during conditions including aging, microdamage, and skeletal disease. A few mechanisms are proposed to control dendrite formation and outgrowth, such as via the regulation of actin polymerization dynamics.SummaryThis review addresses the impact of osteocyte dendrites in bone health and disease. Recent advances in multi-omics, in vivo and in vitro models, and microscopy-based imaging have provided novel approaches to reveal the underlying mechanisms that regulate dendrite development. Future therapeutic approaches are needed to target the process of osteocyte dendrite formation.
Potential Antimicrobial and Antibiofilm Properties of Copper Oxide Nanoparticles: Time-Kill Kinetic Essay and Ultrastructure of Pathogenic Bacterial Cells
Authors: Shehabeldine Amr M. , Amin Basma H. , Hagras Fatouh A. , Ramadan Amr A. , Kamel Mohamed R. , Ahmed Mohamed A. , Atia Kareem H. , Salem Salem S. 
Published: September 2022

AbstractMycosynthesis of nanoparticle (NP) production is a potential ecofriendly technology for large scale production. In the present study, copper oxide nanoparticles (CuONPs) have been synthesized from the live cell filtrate of the fungus Penicillium chrysogenum. The created CuONPs were characterized via several techniques, namely Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), transmission electron microscope (TEM), scanning electron microscope (SEM), and energy-dispersive X-ray spectroscopy (EDX). Furthermore, the biosynthesized CuONPs were performed against biofilm forming Klebsiella oxytoca ATCC 51,983, Escherichia coli ATCC 35,218, Staphylococcus aureus ATCC 25,923, and Bacillus cereus ATCC 11,778. The anti-bacterial activity result was shown with the zone of inhibition determined to be 14 ± 0.31 mm, 16 ± 0.53 mm, 11 ± 0.57 mm, and 10 ± 0.57 mm respectively. Klebsiella oxytoca and Escherichia coli were more susceptible to CuONPs with minimal inhibitory concentration (MIC) values 6.25 and 3.12 µg/mL, respectively, while for Staphylococcus aureus and Bacillus cereus, MIC value was 12.5 and 25 μg/mL, respectively. The minimum biofilm inhibition concentration (MBIC) result was more evident, that the CuONPs have excellent anti-biofilm activity at sub-MIC levels reducing biofilm formation by 49% and 59% against Klebsiella oxytoca and Escherichia coli, while the results indicated that the MBIC of CuONPs on Bacillus cereus and Staphylococcus aureus was higher than 200 μg/mL and 256 μg/mL, respectively, suggesting that these CuONPs could not inhibit mature formatted biofilm of Bacillus cereus and Staphylococcus aureus in vitro. Overall, all the results were clearly confirmed that the CuONPs have excellent anti-biofilm ability against Klebsiella oxytoca and Escherichia coli. The prepared CuONPs offer a smart approach for biomedical therapy of resistant microorganisms because of its promoted antimicrobial action, but only for specified purposes.
An extended best–worst multiple reference point method: application in the assessment of non-life insurance companies
Authors: Bilbao-Terol Amelia , Arenas-Parra Mar , Quiroga-García Raquel , Bilbao-Terol Celia 
Published: September 2022

AbstractIn this paper a multi-criteria decision-making (MCDM) method is developed to rank a set of insurance companies. The proposed method is based on combining two MCDM methods: Extended Best–Worst (EBW) and Multiple Reference Point (MRP) methods. We formulate the problem of finding a priority vector from a set of interval pairwise comparisons applying an EBW method which allows the decision maker (DM) to use interval values in order to describe the relative importance of one criterion over another. The EBW method, using fuzzy set theory, can successfully handle the vagueness and ambiguity present in the judgments. Lastly, the MRP method is employed to obtain an overall score for each company using the weights established at the first stage. A case study is presented to rank Spanish non-life insurance companies based on the constructed model. Since the evaluation of insurance companies involves a great number of indicators, it is a complex MCDM issue. The results show the effectiveness of the proposed method and offer an insightful reference for an evaluation of the insurance industry.
A Brain-Controlled Vehicle System Based on Steady State Visual Evoked Potentials
Authors: Zhang Zhao , Han Shuning , Yi Huaihai , Duan Feng , Kang Fei , Sun Zhe , Solé-Casals Jordi , Caiafa Cesar F. 
Published: September 2022

AbstractIn this paper, we propose a human-vehicle cooperative driving system. The objectives of this research are twofold: (1) providing a feasible brain-controlled vehicle (BCV) mode; (2) providing a human-vehicle cooperative control mode. For the first aim, through a brain-computer interface (BCI), we can analyse the EEG signal and get the driving intentions of the driver. For the second aim, the human-vehicle cooperative control is manifested in the BCV combined with the obstacle detection assistance. Considering the potential dangers of driving a real motor vehicle in the outdoor, an obstacle detection module is essential in the human-vehicle cooperative driving system. Obstacle detection and emergency braking can ensure the safety of the driver and the vehicle during driving. EEG system based on steady-state visual evoked potential (SSVEP) is used in the BCI. Simulation and real vehicle driving experiment platform are designed to verify the feasibility of the proposed human-vehicle cooperative driving system. Five subjects participated in the simulation experiment and real the vehicle driving experiment. The outdoor experimental results show that the average accuracy of intention recognition is 90.68 ± 2.96% on the real vehicle platform. In this paper, we verified the feasibility of the SSVEP-based BCV mode and realised the human-vehicle cooperative driving system.
Sulphur Isotopic Evidence for Upwelling of Anoxic Deep Water as the Cause of End-Permian Mass Extinction from Guryul Ravine Permo-Triassic Boundary Section, Kashmir, India
Authors: Rashid Shaik A. , Absar Nurul , Ganai Javid A. , Raza Mohd. Qaim 
Published: September 2022

Abstract
The Guryul ravine section in Kashmir, northern India represent archetypal Permian-Triassic Boundary (PTB) section, comprising conformable successions of mixed siliciclastic-carbonate sediments deposited in deep-shelf setting. Availability of high quality sedimentological and fossil records provides unique opportunity to examine the oceanic redox condition across PTB. Here, pyrite sulphur isotopic data, along with total organic carbon (TOC) and redox-sensitive trace elements (RSE) is reported from ~28m thick succession across the PTB and attempted to investigate the reason behind the biotic crisis. The TOC and RSE data support an overall anoxic condition with a broad de-oxygenation trend with time. Majority of pyrite sulphur isotope data, considering ~17‰ δ34S of contemporary ocean, show relatively low offset (34SSO4-H2S =16.4-22.4 ‰) between the marine sulphate and sulphide across the PTB, indicating low oceanic dissolved sulphate concentration (1.7-3.6 mM) and an overall oxygen deficient anoxic condition. A high magnitude (~22 ‰) negative δ34S excursion event, observed in this study, broadly correlates with the first peak of mass-extinction at latest Permian H. praeparvus – C. meishanensis Zone. Upwelling of deep Ocean 34S-depleted sulphidic water onto the ocean surface layer best explains the negative δ34S excursion, and it is suggested that H2S poisoning is the main reason of mass mortality. The long term ocean stagnation and widespread ocean anoxia might have been caused by high-surface temperature related to gigantic release of greenhouse gases to the atmosphere during Siberian trap magmatism.
Epithermal Vanadium Mineralization in Sonia Sandstone of Marwar Supergroup, India
Authors: Gaur Virendra , Shrivastava K.L. , Hukmaram  , Sharma Seema , Kumar Pawan , Harsh Anshul , Parihar V. S. 
Published: September 2022

Abstract
Present study of vanadium mineralization in the Sonia sandstone of Jodhpur Group shows first hydrothermal activity in the Sonia sandstone of Marwar Supergroup. The Sonia sandstone served as a host for the mineralizing solutions. The vanadium mineralization occurred in sandstone- gritty sandstone-conglomerate along faults. Field relationship and petrological study suggests that mineralization is filled by epithermal solutions and provide a better understanding of the timing and nature of the alteration processes. Though the source of the vanadium is not well constrained, but is possibly from the partial melting of banded gneissic complex-II (Sirohi Group), the source (crustal) melt had assimilated material from the rocks of Sirohi Group in significant amount. Deposition of tuffs at top of Sonia Formation (Chhoti Khatu) and emplacement of last stage Malani dykes suggest that the last phase of Malani magmatism generated heat for the partial melting of banded gneissic complex-II (Sirohi Group). The occurrence of vanadium in sandstone–gritty sandstone–conglomerate from Sonia Formation of Marwar Supergroup has opened a new chapter to explore uranium which generally occurs after vanadium mineralization in conglomeratic sedimentation.
Rare Earth Element Deposits: Sources, and Exploration Strategies
Authors: Balaram V. 
Published: September 2022

Abstract
Rare earth elements (REE) include the lanthanide series (La, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, and Lu) plus Sc and Y. All these metals occur together in different types of REE deposits such as carbonatites, alkali syenites and monazite-rich placers, and are found in more than 250 minerals in the Earth’s crust. The future of the world’s green technologies depends upon their availability and supply. At present, China is responsible for 80% of global REE production. However, countries such as USA, Australia, India, and Kazakhstan also extract and refine significant quantities of REE. These metals occur in primary deposits associated with igneous and hydrothermal processes, and secondary deposits concentrated by sedimentary processes and weathering. However, other types of resources such as ocean bottom sediments, waste rocks in closed mines, river sediments, industrial wastes like red mud, coal, and fly ash have proved to be containing significant amounts of these elements. Besides the beach sand deposits, the Amba Dongar carbonatite complex, and carbonatite plugs hosting REE deposits at Kamthai have been recognized as a potential REE resource in India. Significant concentrations of REE were identified in the deep-sea sediments of Afanasy Niktin Seamount in the Indian Ocean. Integrated exploration methods are playing a key role in the search for new REE mineral deposits. During geochemical exploration studies, portable analytical instruments such as pXRF, pLIBS, portable Raman spectrometer, and a couple of nuclear techniques have enabled successful results in recent times both on and off the land at lower costs, and allowing rapid decision-making on exploration strategies directly in the field.
The Occurrence of Platinum (Pt) and Skaergaardite (Pd Cu) in the Hutti Underground Gold Mines, Eastern Dharwar Craton, Karnataka, India
Authors: Raju P.V. Sunder , Sangurmath Prabhakar 
Published: September 2022

Abstract
The novelty of this study consists, use of the Powder X-Ray Diffraction (PXRD) technique facility at CSIR-NGRI to report the occurrence of platinum and skaergaardite (Pd Cu) in the Hutti underground gold mines. This study utilized a quartz-bearing sample from the Hutti underground gold mines. One of the split samples were analyzed by PXRD. In this study, quartz samples are found to be associated with sulphides composed of pyrite, chalcopyrite, and arseno-pyrite with intense chemical alterations. The mineral phase of skaergaardite shows a strong intensity at 2θ 43.5° and confirmed with database of International Centre for Diffraction Data Powder Diffraction File – ICDD-2021-PDF4+ PDF00-057-0606 and native platinum, syn (Pt) Pt 0.0999 Sn 0.001 matched with PDF 04-001-3300. Further research work is planned on this interesting mineral association with primary gold ore in Hutti underground gold mine.