bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eating disorders and their impact during the gestational period
Authors: Silva Fernanda B. , Pietro Luciana 
Published: June 2022

Introduction: Eating disorders can cause numerous problems for the physiology of the female body and consequences, such as infertility and difficulties during pregnancy and childbirth, can occur if they are present during a woman's reproductive age. Objective: The objective of this research was to analyze the impacts for mother and child that may be somehow related to the nutritional deficiency, whether active or not, of these women. Methodology: The methodology used was a bibliographic survey in the platforms PubMed, BIREME, SCIELO, using combinations of the following keywords in English: Eating Disorder AND Pregnancy, Anorexia, Bulimia. Result: According to the studies analyzed, the existence of some type of eating disorder, whether active or not, had a negative impact on the pregnancies of these women. Miscarriages, stillborn babies, premature birth, premature placental displacement, small newborn gestational age, umbilical cord knots and even neurological deficits could occur. Discussion: Low body mass index (BMI) was one of the main subjects of discussion in the studies, since it can increase the risk of pregnancy because the mother’s nutrients are crucial for a healthy gestation. Thus, it was concluded that medical, nutritional and psychological follow-up are essential for women with eating disorders, regardless of type, to be able to have a safe pregnancy for themselves and their babies. Keywords: Eating disorders; Mother-child impacts; Nervous bulimia; Anorexia nervosa; Gestational complications.
Bioecology and Domiciliation of the Alkali Bee, Hoplonomia westwoodi (Gribodo, 1894) (Hymenoptera: Halictidae: Nomiinae) from India
Authors: Vijayakumar K T , Taredahalli Nayimabanu , Pannure Arati 
Published: June 2022

We describe here nesting biology of Hoplonomia westwoodi, a common ground nesting solitary bee in India. A typical nest consisted of a straight main tunnel with the cells arranged horizontally at the end. Number of cells per nest ranged from 2 to 4 (x̄ = 2.67). Polypropylene bag and pot culture studies, to evaluate soil types preferred by the bees for nesting, showed that red soil + FYM (1:1) was the most preferred substrate with an average of 12.67 nests/bag. Maximum foraging activity was between 8:00 -13:00 hours. Though H. westwoodi bees were active throughout the year, higher foraging activity was observed between March to June. The species being polylectic, foraged on flowers of several families including Myrtaceae, Lamiaceae, Portulacaceae, Convolvulaceae, Lythraceae, Meliaceae, Rubiaceae, Solanaceae, Cucurbitaceae, Asteraceae, Fabaceae and Malvaceae. A cleptoparasite, Eupetersia sp. was observed in the nests of H. westwoodi, which is the first record of Eupetersia sp. parasitisation on the genus Hoplonomia.
Das Büro – Eine Einführung
Authors: Käfer Alina , Bockstahler Milena , Jurecic Mitja 
Published: June 2022

ZusammenfassungDer vorliegende Einführungsbeitrag stellt verschiedene Forschungsergebnisse des Fraunhofer IAO vor, welche die veränderten Anforderungen an die Arbeits- und Bürowelt aufzeigen. Darüber hinaus werden Erfolgsfaktoren für die Gestaltung zukünftiger Arbeits- und Büroumgebungen dargestellt, insbesondere für die erfolgreiche Zusammenarbeit innerhalb von Teams. Schließlich werden beispielhaft Einsatzmöglichkeiten von Informations- und Kommunikationstechnologie (IKT) beschreiben.Die COVID19-Pandemie ist ein einschneidendes Ereignis für die Arbeitswelt: viele Arbeitnehmende nutzen seitdem vollständig oder ergänzend zur Büroarbeit mobiles Arbeiten, um von zu Hause aus arbeiten zu können. Hybride Arbeitsmodelle, wie das kombinierte Arbeiten im Büro und von zu Hause aus oder unterwegs sind inzwischen in der breiten Masse der Unternehmen und für Wissensarbeitenden angekommen.Unsere Studien zeigen, dass Beschäftigte vor allem für Konzentrationsarbeit und (Video‑)Telefonate gerne von zu Hause aus arbeiten, da sie diese Tätigkeiten dort besser erledigen können. Gründe hierfür liegen unter anderem in den Störfaktoren: So hat sich gezeigt, dass sich ein Großteil der Befragten bei ihrer Arbeit im Büro wesentlich gestörter fühlen als bei der Arbeit zu Hause, was wiederum auch mit den Arbeitsverhältnissen zu Hause zusammenhängt (u. a. Betreuungssituation, eigenes Arbeitszimmer). Bei der räumlich verteilten Zusammenarbeit muss zwingend darauf geachtet werden, dass der Informationsfluss zwischen den Mitarbeitenden, die Kreativität und die Produktivität nicht leiden. Unsere Studien belegen zudem, dass vor allem die persönliche Kommunikation und Kollaboration mit Kolleginnen und Kollegen wichtige Attraktoren sind, um in das Büro zu(rückzu)kehren.Jeder Besuch im Büro folgt einer bewussten Entscheidung, z. B. soziales Netzwerken oder ob alle Aufgaben im Tagesverlauf effizient erledigt werden können. Bei der Gestaltung von Arbeits- und Büroumgebungen zeigt sich, dass vor allem vielfältige Arbeitsumgebungen mit unterschiedlichen Flächen für Zusammenarbeit, aber auch für Rückzug zur individuellen, fokussierten Einzelarbeit entscheidende Erfolgsfaktoren darstellen und zur Zufriedenheit der Mitarbeitenden wesentlich beitragen. Dabei ist vor allem auch die Flexibilität und individuelle Anpassbarkeit der Raum- und Bürostruktur von großer Bedeutung.Die Ergebnisse der Studien zeigen, dass die Arbeits- und Büroflächen vielfältiger, flexibler und teamzentrierter werden müssen, um den sich verändernden Anforderungen gerecht zu werden. Mitarbeitenden sollten für jede ihrer Tätigkeiten den optimalen Arbeitsort und die für sie notwendigen technologischen Arbeitsmöglichkeiten bereitgestellt werden. Dabei kann der zielgerichtete Einsatz von Informations- und Kommunikationstechnologie unterstützen.Für Unternehmen empfiehlt sich, die Bedürfnisse und Tätigkeiten ihrer Mitarbeitenden genauer als bisher zu analysieren, um möglichst passgenaue Lösungen für die zukünftige, hybride Arbeits- und Bürowelt zu entwickeln.
Suggestions on leading an academic research laboratory group
Authors: Church Frank C. 
Published: June 2022

Abstract
This commentary is about running an academic research laboratory group, including some reflections, memories, and tips on effectively managing such a group of scientists focused on one’s research. The author’s academic career has spanned from 1982 to 2022, including postdoctoral research associate through the rank of professor with tenure. Currently, the author is in the final year of 3 years of phased retirement. One must be willing to work hard at running a research laboratory. Also, stay focused on funding the laboratory tasks and publishing one’s work. Recruit the best people possible with advice from the collective laboratory group. Laboratory group members felt more like they were a part of a collective family than simply employees; however, what works best for the researcher is what matters. Several other points to discuss will include managing university roles, recruiting laboratory personnel, getting recognition, dealing with intellectual property rights, and publishing work. In closing, there are many more positives than negatives to leading a research laboratory group. Finally, one cannot replace the unforgettable memories and the legacy of a research laboratory group.
Sorafenib inhibits ovarian cancer cell proliferation and mobility and induces radiosensitivity by targeting the tumor cell epithelial–mesenchymal transition
Authors: Tian Chuntao , Liu Ying , Xue Lingfei , Zhang Dong , Zhang Xiaotong , Su Jing , Chen Jiaohong , Li Xiangke , Wang Liuxing , Jiao Shunchang 
Published: June 2022

Abstract
Sorafenib, a pan-protein kinase inhibitor, inhibits the activity of various kinases (like vascular endothelial growth factor, platelet-derived growth factor, and rapidly accelerated fibrosarcoma) and clinically has been used to treat different human cancers. This study investigated its antitumor activity in ovarian cancer and the underlying molecular events. To achieve that, ovarian cancer SKOV-3 cells were treated with or without sorafenib (10 µM), transforming growth factor (TGF)-β1 (10 ng/mL), sorafenib (10 µM) + TGF-β1 (10 ng/mL), and TGF-β1 (10 ng/mL) + Ly2157299 (5 µM), followed by 8-Gy radiation. The cells were then subjected to cell viability, wound healing, Transwell, caspase-3 activity, and western blot assays. TGF-β1 treatment enhanced ovarian cancer cell epithelial–mesenchymal transition (EMT), whereas sorafenib and a selective TGF-β1 inhibitor Ly2157299 reversed tumor cell EMT, invasion, and expression of EMT markers (E-cadherin and vimentin). Sorafenib and Ly2157299 treatment also significantly reduced the tumor cell viability. Furthermore, both sorafenib and Ly2157299 significantly enhanced ovarian cancer cell radiosensitivity, as assessed by a caspase-3 activity assay. In conclusion, sorafenib inhibited ovarian cancer cell proliferation and mobility and induced tumor cell radiosensitivity. Molecularly, sorafenib could inhibit the TGF-β1-mediated EMT. Future studies will assess sorafenib anti-ovarian cancer activity plus TGF-β1 inhibitors in ovarian cancer in vivo.
Influence of Laser Marking on Microstructure and Corrosion Performance of Martensitic Stainless Steel Surfaces for Biomedical Applications
Authors: Henriksen N. G. , Andersen O. Z. , Jellesen M. S. , Christiansen T. L. , Somers M. A. J. 
Published: June 2022

Abstract
The medical device industry demands unique device identification (UDI) tags on metallic components applied via laser marking. A common issue is that the visual appearance of the marking becomes poorly legible over time due to loss of contrast. Nanosecond pulsed laser irradiation was used to grow an oxide layer on two different martensitic stainless steels AISI 420F mod and 420B to compare the influences of the chemical composition of the steel (with and without S), power density, and energy input. The corrosion behavior was found to depend strongly on laser energy input. The presence of sulfur negatively affected the corrosion resistance and narrowed the applicable window for the laser processing parameters significantly. For the sulfur-containing AISI 420F steel, 3‒5 μm wide craters formed on the surface after laser marking, which is interpreted as thermal degradation of protruding MnS inclusions resulting from the laser marking process. Also, substantial cracking in the oxide layer was observed. The marked specimens suffered from corrosion in a thin zone below the formed oxide layer. This behavior is attributed to Cr-depletion in the zone adjacent to the oxide layer, resulting from providing Cr to the growing oxide layer.
Spatial single mode laser source interaction with measured pulse based parabolic index multimode fiber
Authors: Rashed Ahmed Nabih Zaki , Ahammad S.K. Hasane , Daher Malek G. , Sorathiya Vishal , Siddique Abrar , Asaduzzaman Sayed , Rehana Hasin , Dutta Nitul , Patel Shobhit K. , Nyangaresi Vincent Omollo , Jibon Rayhan Habib , Abdelhamid Huda Said 
Published: June 2022

Abstract
The study clarified spatial single mode laser interaction with measured pulse based parabolic index multimode fiber. Peak power level margin, maximum/minimum signal amplitude margin after parabolic index multimode fiber are measured with core radius of 25 µm, cladding thickness of 10 µm, refractive index peak of 1.4142, length of 300 m, and refractive index step of 1%. Maximum signal power margin against spectral frequency after PIN light detector based parabolic fiber properties is tested under the same operating parameters. The signal power amplitude/power within parabolic index multimode fiber is also measured based on variations of fiber lengths and relative refractive index step. The study implies the multimode graded index fibers with parabolic or near parabolic index profile cores have transmission bandwidths than other multimode fibers.
Maternal plasma cytokines and the subsequent risk of uterine atony and postpartum hemorrhage
Authors: Gallo Dahiana M. , Romero Roberto , Bosco Mariachiara , Chaiworapongsa Tinnakorn , Gomez-Lopez Nardhy , Arenas-Hernandez Marcia , Jung Eunjung , Suksai Manaphat , Gotsch Francesca , Erez Offer , Tarca Adi L. 
Published: June 2022

Abstract

Objectives
To determine whether the maternal plasma concentrations of cytokines are higher in pregnant women with postpartum hemorrhage (PPH) compared to pregnant women without PPH.

Methods
A retrospective case-control study included 36 women with PPH and 72 matched controls. Cases and controls were matched for gestational age at delivery, labor status, delivery route, parity, and year of sample collection. Maternal plasma samples were collected up to 3 days prior to delivery. Comparison of the plasma concentrations of 29 cytokines was performed by using linear mixed-effects models and included adjustment for covariates and multiple testing. A false discovery rate adjusted p-value <0.1 was used to infer significance. Random forest models with evaluation by leave-one-out and 9-fold cross-validation were used to assess the combined value of the proteins in predicting PPH.

Results
Concentrations of interleukin (IL)-16, IL-6, IL-12/IL-23p40, monocyte chemotactic protein 1 (MCP-1), and IL-1β were significantly higher in PPH than in the control group. This difference remained significant after adjustment for maternal age, clinical chorioamnionitis, and preeclampsia. Multi-protein random forest proteomics models had moderate cross-validated accuracy for prediction of PPH [area under the ROC curve, 0.69 (0.58–0.81) by leave-one-out cross validation and 0.73 (0.65–0.81) by 9-fold cross-validation], and the inclusion of clinical and demographic information did not increase the prediction performance.

Conclusions
Pregnant women with severe PPH had higher median maternal plasma concentrations of IL-16, IL-6, IL-12/IL-23p40, MCP-1, and IL-1β than patients without PPH. These cytokines could serve as biomarkers or their pathways may be therapeutic targets.
Nano-engineered vitamins as a potential epigenetic modifier against environmental air pollutants
Authors: Ratre Pooja , Chauhan Prachi , Bhargava Arpit , Tiwari Rajnarayan , Thareja Suresh , Srivastava Rupesh Kumar , Mishra Pradyumna Kumar 
Published: June 2022

Abstract
Air pollution has emerged as a serious threat to human health due to close association with spectrum of chronic ailments including cardiovascular disorders, respiratory diseases, nervous system dysfunctions, diabetes and cancer. Exposure to air-borne pollutants along with poor eating behaviours and inferior dietary quality irreversibly impacts epigenomic landscape, leading to aberrant transcriptional control of gene expression which is central to patho-physiology of non-communicable diseases. It is assumed that nutriepigenomic interventions such as vitamins can control such adverse effects through their immediate action on mitochondrial epigenomic-axis. Importantly, the exhaustive clinical utility of vitamins-interceded epigenetic synchronization is not well characterized. Therefore, improving the current limitations linked to stability and bioavailability issues in vitamin formulations is highly warranted. The present review not only sums up the available data on the role of vitamins as potential epigenetic modifiers but also discusses the importance of nano-engineered vitamins as potential epidrugs for dietary and pharmacological intervention to mitigate the long-term effects of air pollution toxicity.
Functional changes in brain oscillations in dementia: a review
Authors: Giustiniani Andreina , Danesin Laura , Bozzetto Beatrice , Macina AnnaRita , Benavides-Varela Silvia , Burgio Francesca 
Published: June 2022

Abstract
A growing body of evidence indicates that several characteristics of electroencephalography (EEG) and magnetoencephalography (MEG) play a functional role in cognition and could be linked to the progression of cognitive decline in some neurological diseases such as dementia. The present paper reviews previous studies investigating changes in brain oscillations associated to the most common types of dementia, namely Alzheimer’s disease (AD), frontotemporal degeneration (FTD), and vascular dementia (VaD), with the aim of identifying pathology-specific patterns of alterations and supporting differential diagnosis in clinical practice. The included studies analysed changes in frequency power, functional connectivity, and event-related potentials, as well as the relationship between electrophysiological changes and cognitive deficits. Current evidence suggests that an increase in slow wave activity (i.e., theta and delta) as well as a general reduction in the power of faster frequency bands (i.e., alpha and beta) characterizes AD, VaD, and FTD. Additionally, compared to healthy controls, AD exhibits alteration in latencies and amplitudes of the most common event related potentials. In the reviewed studies, these changes generally correlate with performances in many cognitive tests. In conclusion, particularly in AD, neurophysiological changes can be reliable early markers of dementia.
Status quo und Ausgabenprojektionen der Beamtenversorgung
Authors: Raffelhüschen Bernd , Kohlstruck Tobias 
Published: June 2022

Da die Beamtenpopulation deutlich älter als die Gesamtbevölkerung ist, gehen die kohortenstarken Jahrgänge bereits in den Ruhestand. Allein in den letzten zehn Jahren haben sich die jährlichen Versorgungsausgaben der Gebietskörperschaften um 50 % erhöht, wovon insbesondere die (westdeutschen) Bundesländer betroffen sind. In den kommenden Jahren ist mit einem weiteren Anstieg der Versorgungsausgaben zu rechnen, wobei sich der rein demografische Effekt bis Ende des Jahrzehnts abschwächen wird. Auch wenn die Altersstruktur der Beamten sowie verfassungsrechtliche Vorgaben einer schnellen Verringerung der Versorgungsausgaben entgegenstehen, sollte der Staat in Zukunft auf eine restriktivere Verbeamtungspolitik mit Augenmaß und eine deutlich stärkere Kapitaldeckung der Versorgungszusagen setzen, um die intergenerative Ungleichverteilung zu verringern.
Análisis energético en lecherías de la región pampeana Argentina. Parte 1. Flujos de energía
Authors: Gimenez Gustavo Daniel , Novaira Bruno Idelfonso , Marini Pablo Roberto 
Published: June 2022

Introducción. La heterogeneidad de los sistemas agropecuarios dificulta evaluar su sustentabilidad, pues no existen herramientas que puedan aplicarse a la generalidad de los casos, con indicadores de fácil comprensión por los actores del medio. Una herramienta de uso posible es el análisis energético. Objetivos. Contextualizar la heterogeneidad de los modelos de producción primaria de leche, con base en flujogramas de energía. Materiales y métodos. Se trabajó con datos retrospectivos de nueve establecimientos comerciales de producción de leche en la Región Pampeana Argentina, durante el período comprendido entre julio de 2014 a junio de 2015. Estos se diferenciaron según variables como carga animal y nivel de suplementación alimentaria. Se utilizó la metodología de estudio de casos, con análisis energéticos para cada caso, configurándose para cada uno flujogramas y cuantificándose ingresos, egresos y eficiencia de uso de la energía. Resultados. Se determinó la existencia de tres tipos de sistemas: mixto lechero-agrícola con invernada (proceso de engorde), mixto lechero-agrícola y lechero puro con invernada. Los sistemas mixtos son importantes por el caudal energético que aportan la agricultura, para compensar la significativa pérdida de energía de los subsistemas de leche y carne; sin embargo, los sistemas ganaderos puros resultaron más eficientes en el uso de la energía, debido al menor consumo energético y a la producción forrajera. Conclusiones. El análisis energético resultó útil para caracterizar la heterogeneidad entre sistemas a partir de la construcción de flujogramas. También permitió evaluar aspectos sociales y ambientales, que en análisis tradicionales quedan excluidos; pero que, dado el volumen del flujo energético que proveen, motivan la necesidad de incluirlos en la contabilidad por su importancia para el proceso lechero y por el estrecho vínculo entre naturaleza y sociedad, asociado al complejo hombre-ecosistema.
Unsur Kualitas Layanan dan Nilai Pelanggan sebagai Pembentuk Kepuasan Pelanggan di PT Bank BNI 1946 Cabang UPI Bandung
Authors: Mulyadi Ajang 
Published: June 2022

AbstractThe aim of this research is to determine and analyze the service quality of PT Bank BNI Branch Office UPI Bandung, the customer value of PT Bank BNI Branch Office UPI Bandung, the customer satisfaction of PT Bank BNI Branch Office UPI Bandung, and the influence of the elements of service quality and customer value on customer satisfaction of PT Bank BNI Branch Office UPI Bandung. The method used is a survey method. Data collected through distributing questionnaires to the respondents. The population in this study is lecturers and employees of the Indonesian Education University (UPI) who are customers of Bank BNI Branch UPI, as many as 1,807 people. The results of this study revealed that in general the quality of services in a category well enough, customers benefit from the services offered by banks, and customers feel quite satisfied with the bank services. The study also reveals the quality of customer service and value has a positive influence and significantly to customer satisfaction. This implies that the bank management efforts to improve customer satisfaction can be started from efforts to improve service quality and customer value.
STUDI AKUNTABILITAS USAHA MIKRO KECIL MENENGAH, DINAS KOPERASI DAN DINAS PERINDUSTRIAN KABUPATEN LAMONGAN
Authors: Nugrahadi Eko Warsiyanto , Basuki Basuki 
Published: June 2022

Jumlah UMKM berkembang 4% tiap tahun, yang menjadikan UMKM sebagai roda perekonomian Indonesia serta menyumbang setengah dari PDB Indonesia. Namun, angka tersebut tidak didukung oleh pengelolaan manajemen yang profesional dari para pelaku UMKM. Diterapkannya SAK EMKM dimungkinkan memberikan standar bagi pengelolaan UMKM yang modern. Kenyataannya banyak UMKM yang tidak mengetahui adanya standar ini apalagi melaksanakannya. Standar ini mewajibkan para pelaku UMKM untuk melakukan akuntabilitas dari sisi keuangan, antara lain dengan menyiapkan Laporan Laba/Rugi, Neraca dan Catatan Atas Laporan Keuangan. Apa yang diharapkan tidak sesuai dengan kenyataan, banyak UMKM tidak melaksanakan bentuk akuntabilitas tersebut karena ketidakmampuan sumber daya yang dimiliki. Penelitian ini menggunakan metode kualitatif dengan pendekatan studi kasus eksploratori. Metode ini dipilih karena konteks bentuk ideal dari akuntabilitas keuangan harus dicari karena peneliti ingin mengetahui bentuk ideal pelaksanaan akuntabilitas keuangan yang sesuai dengan sumber daya dan kemampuan yang dimiliki oleh pelaku UMKM. Penelitian ini bertujuan untuk memberikan kerangka yang menunjukkan bentuk ideal akuntabilitas keuangan bagi para UMKM. Hasil penelitian tentang bentuk akuntabilitas UMKM yang dilakukan kebanyakan tidak terstandarisasi dan berbentuk single entry accounting. Kerangka yang ideal untuk akuntabilitas keuangan UMKM adalah, kepemilikan NPWP, Laporan Penerimaan/pengeluaran kas, dan Laporan Harga Pokok Penjualan.