bluuebunny/crossref_metadata_2025_split huggingface dataset:
Might be the forced aeration an alternative to improve the efficiency of composting and quality of fertilizer?
Authors: de Oliveira Juliana Dias , Orrico Ana Carolina Amorim , Vilela Ranielle Nogueira da Silva , Junior Marco Antonio Previdelli Orrico , Borquis Rusbel Raul Aspilcueta , Tomazi Michely , Leite Brenda Kelly Viana 
Published: July 2022

Abstract
The objective of this study was to evaluate the influence of forced aeration and season on hatchery waste composting in static windrows with perforated walls. there were three well-defined thermophilic phases during composting, with the first occurring immediately after the formation of the windrows and the others occurring after turnovers at 50 and 70 days of composting. Aeration resulted in greater degradation (p<0.01) of volatile solids (VS), carbon (C), and lignin in the composting windrows during the summer up to 50 days of process, in comparison to no aeration piles. However, at 70 and 90 days of composting, the results were similar between aerated and nonaerated windrows. The greatest (p<0.01) degradation of nitrogen (N) occurred during the winter and in the absence of aeration (55.25%). Season influenced (p<0.05) the concentrations of humic acids, and they were higher in the compost generated during the summer than generated during the winter. The concentrations of Mg, Fe and Na were influenced by the season, with higher values (p<0.01) in the summer, however they were not affected by aeration. In the winter, aeration is recommended after 50 days of composting, whereas in summer, forced aeration is beneficial for N conservation and humic acid formation.
Plurimorphous plurihormonal Pit-1 positive macroadenoma with central hyperthyroidism: a rare case report and literature review
Authors: Peng Guiliang , Guo Chuanhong , Lv Yangfan , Zhou Ling , Shen Rufei , Chen Yong , Zheng Xin , Sun Zheng , Zheng Hongting , Long Min 
Published: July 2022

Abstract
Background
Thyrotropin (TSH)-secreting pituitary neuroendocrine tumors (PitNETs) are pretty rare pituitary adenomas, occasionally accompanied by hypersecretion of other anterior pituitary hormones: growth hormone (GH) and prolactin (PRL). The clinical, biochemical, and pathological characteristics may represent diverse circumstances.
Case presentation:
In this report, a 33-year-old woman diagnosed with TSH PitNET co-secreting GH presented no obvious clinical symptoms. The main characteristics were elevated TSH, fT3, and fT4 levels accompanied by slightly elevated GH and IGF-1levels. The magnetic resonance imaging (MRI) detected a pituitary macroadenoma (18×16×16mm) with cavernous sinus and suprasellar invasion. The immunohistochemistry revealed diffuse positivity for TSH, strong immunoreactivity for GH, and sporadic positivity for PRL. The electron microscope and double immunofluorescence staining confirmed that a plurimorphous plurihormonal adenoma produced TSH, GH, and PRL. After preoperative somatostatin receptor ligands (SRLs) treatment and transsphenoidal surgery, the patient achieved clinical and biochemical remission during follow-up.
Conclusion
In the TSH PitNET, the positive immunohistochemistry for TSH, GH, and PRL translated into hormonal overproduction with TSH and GH.
Essential oil from the leaves of Eugenia pohliana DC. (Myrtaceae) alleviate nociception and acute inflammation in mice
Authors: Nascimento Andreza Larissa , Guedes Joyce Bezerra , Costa Wêndeo Kennedy , de Veras Bruno Oliveira , de Aguiar Júlio César Ribeiro de Oliveira Farias , Navarro Daniela Maria do Amaral Ferraz , Correia Maria Tereza dos Santos , Napoleão Thiago Henrique , de Oliveira Alisson Macário , Silva Márcia Vanusa da 
Published: July 2022

Abstract
Eugenia pohliana (Myrtaceae) is used in folk medicine by communities in Brazil. However, there are no reports on its biological activity. This is the first to identify the components of E. pohliana essential oil (EpEO) and evaluate their antinociceptive and anti-inflammatory activities in an in vivo model at doses of 25, 50, and 100 mg/kg. The essential oil (EO) was obtained by hydrodistillation, and the analysis was performed by gas chromatography coupled with mass spectrometry. Antinociceptive activity was evaluated by writhing tests, tail movement, and formalin (neurogenic and inflammatory pain); naloxone was used to determine the nociception mechanism. Anti-inflammatory activity was assessed by edema and peritonitis tests. We found that (E)-β-caryophyllene (BCP) (15.56%), δ-cadinene (11.24%) and α-cadinol (10.89%) were the major components. In the writhing test, there was a decrease in writhing by 42.95–70.70%, in the tail movement, an increase in latency time by 69.12–86.63%, and in the formalin test, there was a reduction in pain neurogenic by 29.54–61.74%, and inflammatory pain by 37.42–64.87%. The antinociceptive effect of EpEO occurs through the activation of opioid receptors. In addition to antinociceptive activity and mechanism, a reduction in inflammation by 74.93‒81.41% was observed in the paw edema test and inhibition of the influx of leukocytes by 51.86‒70.38% and neutrophils by 37.74‒54.72% in the peritonitis test. It was concluded that EpEO has antinociceptive pharmacological properties with opioid and anti-inflammatory actions, and that its use does not cause hemolytic damage or behavioral change.
A strong association between the VDR gene markers and SARS-CoV-2 variants
Authors: Mamurova Begimai , Akan Gokce , Tuncel Gulten , Mogol Evren , Evren Emine Unal , Evren Hakan , Suer Huseyin Kaya , Sanlidag Tamer , Ergoren Mahmut Cerkez 
Published: July 2022

Abstract
IntroductionA COVID-19 disease, caused by the SARS-CoV-2, created significant concern since December 2019 worldwide. The virus is known to be highly transmissible. Heterogenic clinical features even vary more among SARS-CoV-2 variants from asymptomatic forms to severe symptoms. Previous studies revealed an association between COVID-19 and vitamin D deficiency resulting from its low levels in COVID-19 patients. To our knowledge, there is no scientific investigation that evaluates the direct association between SARS-CoV-2 variants of concern and VDR gene markers in Cyprus. Thus, the present study aimed to identify the putative impact of VDR gene polymorphisms on SARS-CoV-2 infection among different variants.MethodsThe nasopharyngeal swabs were taken from a total number of 600 patients who were admitted to Near East University Hospital COVID-19 PCR Diagnosis Laboratory for routine SARS-CoV-2 RT-qPCR test. The RT-qPCR negative resulting samples were taken as control samples (n = 300). On the other hand, the case group consisted of patients who were SARS-CoV-2 RT-qPCR positive, infected with either SARS-CoV-2 Alpha (n = 100), Delta (n = 100), or Omicron (n = 100) variants. Two VDR gene polymorphisms, TaqI-rs731236 T > C and FokI-rs10735810 C > T, were genotyped by PCR-RFLP.ResultsThe mean age of the COVID-19 patient’s ± SD was 46.12 ± 12.36 and 45.25 ± 12.71 years old for the control group (p > 0.05). The gender distribution of the patient group was 48.3% female and 51.7% male and for the control group 43% female and 57% male (p > 0.05). Significant differences were observed in genotype frequencies of FokI and TaqI variants between SARS-CoV-2 patients compared to the control group (p < 0.005). Furthermore, the risk alleles, FokI T allele and TaqI C, were found to be statistically significant (OR = 1.80, 95% CI = 1.42–2.29, OR = 1.62, 95% CI = 1.27–2.05, respectively) in COVID-19 patients. The highest number of patients with wild-type genotype was found in the control group, which is 52.9% compared with 17.5% in the case group. Moreover, most of the COVID-19 patients had heterozygous/homozygous genotypes, reaching 82.5%, while 47.1% of the control group patients had heterozygous/homozygous genotypes.ConclusionOur results suggested that patients with FokI and TaqI polymorphisms might tend to be more susceptible to getting infected with the SARS-CoV-2. Overall, findings from this study provided evidence regarding vitamin D supplements recommendation in individuals with vitamin D deficiency/insufficiency in the peri- or post-COVID-19 pandemic.
Determination of water content in direct based resin composites using coulometric Karl Fischer titration
Authors: Faria-e-Silva André Luis , Heckel Lea , Belli Renan , Lohbauer Ulrich 
Published: July 2022

Abstract
Objectives: This study evaluated the water content and sorption of direct composites over 60 days using coulometric Karl Fischer titration (KFT). Methods: Plate-shaped specimens (10 x 10 x 1 mm of thickness) were built up using the composites Clearfil Majesty Posterior (CM), Grandio SO (GS), and Filtek Supreme XT (FS). Water contents were determined in non-stored specimens (control) or after storage in distilled water for up to 60 days (n = 5). The amount of water transferred from the specimens heated at 200°C (isothermal mode) was measured in the Coulometer. Data of water content in wt% and µg/mm3 were individually analyzed by 2-way ANOVA and Tukey`s test (α = 0.05).Results: The water content of non-stored specimens ranged from 0.28 to 1.69 wt% (5.6 to 31.2 μg/mm3) for GS and FT, respectively. The highest values of water sorption were observed for FS (25.3 μg/mm3 after 60 days). GS and CM showed similar water sorption after 60 days (≈ 9 μg/mm3), but an ultimate higher water content was observed for CM (0.9 wt%; 22.0 μg/mm3) than GS (0.7 wt%; 14.8 μg/mm3). In general, for our geometry, water saturation was reached after 21 days. Conclusions: Since all composites presented some base water content, water sorption data alone does not account for the ultimate water content in direct resin-based composites. Clinical relevance: Measuring only weight changes of specimens following water exposure can rank the composites more prone to degradation incorrectly since the base water content strongly affects their final content.
Achieving Eco-Innovative Smart Glass Design with the Integration of Opinion Mining, QFD and TRIZ
Authors: Lee CKM , Tsang YP , Chong WW , Au YS 
Published: July 2022

Abstract

As technology advances, the release of new smart devices accelerates, and thus the disposal of electronic devices has increased exponentially, worsening the gravity of electronic waste all over the world. It is eager to consider eco-friendly product design in order to sustain global supply chains. When addressing customer requirements in new product design, sustainable design thinking should thus be incorporated to create not only innovative, but also sustainable products. The purpose of this research is to build a systematic approach to achieve sustainable new product development. To examine the system effectiveness, smart glasses which are rapidly developed in the era of the metaverse is considered in a case study. By utilizing opinion mining approaches, including wordcloud and TextRank algorithm, to decipher customer needs, quality function deployment (QFD) is used to investigate the existing state of smart glasses, as well as translate customers’ needs into technical requirements that serve as the basis for sustainable new product design. Subsequently, the theory of inventive problem solving (TRIZ) is applied to formulate the contradiction matrix between improvement and preservation areas in order to reach the eco-innovation in a systematic manner. Beyond the theoretical investigation, this study presents the application of the proposed system for the sustainable design of smart glasses, so as to support the next generation of smart glasses.
Characterization of Heavy Metal Fractions in the Soil Developed on Volcanic Rocks of Karadağ Mountain by Sequential Extraction, Turkey
Authors: Özaytekin Hasan Hüseyin , Dedeoğlu Mert 
Published: July 2022

Abstract
In this work, the BCR (Community Bureau of Reference) sequential extraction scheme (exchangeable weak acid-soluble, reducible, oxidizable, and non-extractable metal fractions) was applied to selected soil samples. Soil samples were taken from 15 different sites and the contents of Cd, Cr, Cu, Ni, Pb, and Zn in the mobile and residual fractions of the soils formed on the Karadağ volcanic materials were determined by the BCR (BCR method, currently known as SM&T (the Standards Measurements and Testing Programme) sequential extraction procedure and the mobility of each metal was revealed on the basis of fractions. The order of heavy metals in each fraction of Karadağ samples was observed as follows: Cd: Acid and Water Soluble > Reducible > Oxidizable > Residual; Cr: Residual > Oxidizable > Reducable > Acid and Water Soluble; Cu: Residual > Oxidizable > Reducable > Acid and Water Soluble; Ni: Residual > Reducable > Oxidizable > Acid and Water Soluble; Pb: Reducible > Residual > Oxidizable > Acid and Water Soluble; Zn: Residual > Reducable > Oxidizable > Acid and Water Soluble According to the data obtained, while the concentrations of Cd and Pb in the mobile fraction were higher than those in the residual (immobile) fraction in Karadağ; Cr, Cu, Ni, and Zn were higher in the immobile fraction. When the higher mobility levels of, Cd and Pb are evaluated in terms of environmental pollution and toxicity in soil, these metals have been found to have a higher potential risk than other metals. Because the metals in the first three fractions can dissolve depending on environmental conditions, pollute underground and other water resources, and these metals can be taken up by plants. According to the results obtained, Cd and Pb are likely to be in close contact with plant roots and thus could potentially affect soil fertility. In order to avoid threats to productivity and food security in the long term, it has been determined that further trace metal inputs to soils in these areas should be avoided by agricultural management or other means.
Impact of frozen elephant trunk in the thoracoabdominal aortic repair with normothermic iliac perfusion
Authors: Gao Haoyu , Wang Luchen , Liu Yanxiang , Liang Shenghua , Zhang Bowen , Ren Jie , Yu Cuntao , Sun Xiaogang 
Published: July 2022

Abstract
Background:
The aim of this study was to evaluate the impact of frozen elephant trunk (FET) in thoracoabdominal (TA) aortic repair with normothermic iliac perfusion.
Methods:
From January 2008 to December 2019, 144 patients undergoing TA repair with normothermic iliac perfusion were enrolled in this study. Early and mid-term outcomes of patients with previous FET implantation (group A) were compared with patients without previous FET implantation (group B). The logistic regression analysis was performed to investigate the risk factors for adverse events, which were defined as early death, permanent stroke, permanent paraplegia, or permanent renal failure necessitating dialysis.
Results:
The proximal aortic clamp time and operating time was 14.26 ± 5.57 min and 357.40 ± 94.51 respectively in group A, which were both significantly shorter than that in group B. The incidence of adverse event was significantly lower in group A than that in group B (9.7% vs 25.6%, P = 0.027). There was no significant difference between two groups with regards to other complications or late outcomes. In addition, age > 50 y, a Ccr < 90 ml/min/1.73 m2 and the operating time were identified as significant risk factors through logistic regression analysis for adverse events of TA repair.
Conclusions:
The FET technique simplifies the operative technique of proximal anastomosis, decreases the operating time and improves the early outcomes in TA repair, whereas does not provide a significant benefit with regard to late outcomes. Long-term follow-up and studies with larger sample sizes are necessary for further confirmation.
Association of Anthropometric and Computed Tomography-Based Obesity Indices with Anatomically Distinct Subclinical Atherosclerotic Calcifications
Authors: Hisamatsu Takashi , Higo Yosuke , Nakagawa Yoshihisa , Sawayama Yuichi , Yano Yuichiro , Kadota Aya , Fujiyoshi Akira , Kadowaki Sayaka , Torii Sayuki , Kondo Keiko , Watanabe Yoshiyuki , Ueshima  , Miura Katsuyuki 
Published: July 2022

Abstract
Background
Few studies have compared the strength in the associations of anthropometric and computed tomography (CT)-based obesity indices with coronary artery calcification (CAC), aortic artery calcification (AoAC), and aortic valve calcification (AVC).
Methods
In healthy 931 men (mean age, 63.7 years) from a population-based cohort, we assessed cross-sectional associations of anthropometric and CT-based obesity indices with CAC, AoAC, and AVC. Anthropometric measures included body mass index (BMI), waist circumference, hip circumference, waist-to-hip circumference ratio, and waist-to-height ratio. CT images at the L4/5 level were obtained to calculate the areas of abdominal visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), total adipose tissue (TAT), VAT-to-SAT ratio (VSR), and VAT-to-TAT ratio (VTR). CAC, AoAC, and AVC were quantified using the Agatston score based on CT scanning.
Results
CAC, AVC, and AoAC were present in 348 (62.6%), 173 (18.6%), and 769 (82.6%) participants, respectively. In multivariable models adjusting for age, lifestyle factors, and CT types, anthropometric and CT-based obesity indices were positively associated with CAC (p < 0.01). Conversely, VAT-to-SAT ratio and VAT-to-TAT ratio were positively associated with AoAC (p < 0.01). Any obesity indices were not associated with AVC.
Conclusions
The strength of the associations of obesity indices with subclinical atherosclerosis varied according to the anatomically distinct atherosclerotic lesions, among healthy men.
Physicochemical Characterization of Solid Waste at Transfer Stations
Authors: Beyene Gezahegn Kebede , Imru Abeba Leta 
Published: July 2022

Abstract
Municipalities are producing more solid garbage, and this, along with inadequate and incompetent management, has caused serious environmental issues. The goal of this study was to describe the physicochemical composition of municipal solid waste (MSW) at Dilla town's transfer stations. A rigorous field survey was conducted to gather information, and laboratory testing was carried out to quantify the physiochemical properties of MSW in a few select transfer stations. In order to choose the representative transfer stations from each sub-city, a simple random sample procedure was used. For waste quantification, the solid waste weight analysis method was used. According to the study's findings, organic waste made up the majority of the municipality's solid garbage at transfer stations (70 ), followed by other types of waste (13%), textiles (7%), plastic (5%), paper (3%), medical (1%), and glass (1%). As the findings show, bio-manure can be recovered from a significant fraction of generated wastes that are compostable and recyclable. The municipality, however, did not coordinate private sector investment in waste recycling and reuse. As a result, waste is disposed of indifferently to landfill sites, open spaces, transfer stations, and roadside locations. Therefore, in order to lessen the amount of rubbish that is dumped everywhere and that ends up at transfer stations, the municipality must organize private businesses and sectors to help it share the load by composting and recycling waste into useful resources.
Combined procedure with radial probe and convex probe endobronchial ultrasound
Authors: Chung Hyun Sung , Pak Kyoungjune , Lee Geewon , Eom Jung Seop 
Published: July 2022

Abstract
Background
Concurrent bronchoscopy using radial probe and convex endobronchial ultrasound (RP- and CP-EBUS) is used to simultaneously evaluate both peripheral lung lesions for the histological diagnosis of the primary tumor and mediastinal lymph nodes for mediastinal staging. So far, little is known about the combined procedure with RP- and CP-EBUS.
Methods
Between January 2020 and March 2021, the bronchoscopy database was reviewed to identify the clinical outcomes of the combined procedure with RP- and CP-EBUS. Patients who underwent transbronchial biopsy using RP-EBUS alone were classified as the RP-EBUS group, while those who underwent a combined procedure with RP- and CP-EBUS were classified as the combination group.
Results
The overall diagnostic yield in the combination group was significantly higher than the RP-EBUS group (90.7% vs. 70.0%, P < 0.001). CP-EBUS increased the diagnostic yield of bronchoscopic procedure in the combination group by 9.3%. Although the mean procedure time was significantly longer, and the mean doses of midazolam and fentanyl were significantly higher in the combination group (P < 0.001), there were no differences in the overall complication rates between the two study groups (1.4% and 1.0% for the RP-EBUS and combination groups, respectively, P = 0.766).
Conclusions
Combined bronchoscopy using RP- and CP-EBUS is feasible and safe. Besides mediastinal staging, CP-EBUS increased the overall diagnostic yield of bronchoscopic procedures by 9.3%.
Various Flours in Pastry Production Technology
Authors: Renzyaeva Tamara , Tuboltseva Anna , Renzyaev Anton 
Published: July 2022

Cereals and oilseed flours increase the nutritional value of pastry products. Their composition is different from traditional wheat flour, which means their technological properties are also different. The research objective was to study the functional and technological properties of various types of flour to develop a multicomponent powder mix formulation for functional cookies.
The research included baking wheat flour of the highest grade, whole-wheat flour, corn flour, semi-skimmed flax flour, and rice flour. The flours and their multicomponent mix were tested for functional and technological properties, i.e., water-holding capacity, fat-retaining capacity, fat-emulsifying capacity, emulsion stability, etc.
These propertied appeared to depend on the protein and carbohydrate composition of the flour. The water-holding capacity of the flax flour sample was 6–8 times greater than that of other types, while the fat-retaining capacity of the corn flour sample was 30% higher. Corn and flax flours demonstrated the best fat-emulsifying capacity and emulsion stability. The research resulted in a new multicomponent corn-flour-based powder mix for high-quality butter cookies.
The formulation included corn flour and vegetable oil, which increased the nutritional value of the final product and expanded the range of gluten-free cookies.
Climate change impact on blue and green water resources distributions in the Beijiang River basin based on CORDEX projections
Authors: Dai Chao , Qin Xiaosheng , Dong Feifei , Cai Yanpeng 
Published: July 2022

Abstract
This study assessed the potential impact of climate change on spatiotemporal distribution of blue and green water resources in the Beijiang River basin, southern China, using the SWAT hydrological model and CORDEX-EAS regional climate models (RCMs). The outputs of three RCMs (namely RMOH, RMPI and RNCC) under two emission scenarios (RCP 2.6 and RCP 8.5) were bias-corrected by using the quantile delta mapping method for the control (1975–2004), near future (2021–2050) and far future (2061–2090) periods. Driven by the corrected climate variables, future blue and green water were assessed by using the SWAT model calibrated with streamflow data. The results indicated that the green water flow in the northwest basin predicted by RMOH under RCP 2.6 would increase up to about 2.7% in 2061–2090; RNCC suggests that most of the basin would experience the most significant reduction in green water storage (over 30%) under RCP 8.5 in the far future. For blue water, the ensemble mean of three RCMs indicates a slight decreasing trend in the northern part of the basin and an increasing one in the southern part under RCP 8.5 in the far future. Our findings could help watershed managers evaluate future hydrological risks and design appropriate adaptation strategies.