bluuebunny/crossref_metadata_2025_split huggingface dataset:
Naturally Occurring Steroidal Saponins as Potential Anticancer Agents:
Current Developments and Mechanisms of Action
Authors: Zou Yulin 
Published: March 2022

Abstract:
Cancer is claimed as a prevalent cause of mortality throughout the world. Conventional chemotherapy plays a pivotal role in the treatment of cancers, but multidrug resistance has already become one of the major impediments to efficacious cancer therapy, creating a great demand for the development of novel anticancer drugs. Steroidal saponins, abundantly found in nature, possess ex-tensive structural variability, and some naturally occurring steroidal saponins exhibit profound anti-cancer properties through a variety of pathways. Hence, naturally occurring steroidal saponins are powerful lead compounds/candidates in the development of novel therapeutic agents. This review article described the recent progress of naturally occurring steroidal saponins as potential anticancer agents, and the mechanisms of action were also discussed, covering articles published between 2017 and 2021.
Trait Anger, Hostility, and the Risk of Type 2 Diabetes and Diabetes-
Related Complications: A Systematic Review of Longitudinal Studies
Authors: Deschênes Sonya S. , Mohseni Marzia , Lindekilde Nanna , Forget Geneviève , Burns Rachel J. , Pouwer Frans , Schmitz Norbert 
Published: March 2022

Background:
Research suggests associations between trait anger, hostility, and type 2
diabetes and diabetes-related complications, though evidence from longitudinal studies has not yet
been synthesized.

Objective:
The present systematic review examined findings from longitudinal research on trait
anger or hostility and the risk of incident type 2 diabetes or diabetes-related complications. The review
protocol was pre-registered in PROSPERO (CRD42020216356).

Methods:
Electronic databases (MEDLINE, PsychINFO, Web of Science, and CINAHL) were
searched for articles and abstracts published up to December 15, 2020. Peer-reviewed longitudinal
studies with adult samples, with effect estimates reported for trait anger/hostility and incident diabetes
or diabetes-related complications, were included. Title and abstract screening, full-text
screening, data extraction, and quality assessment using the Newcastle-Ottawa Scale were conducted
by two independent reviewers. A narrative synthesis of the extracted data was conducted
according to the Synthesis Without Meta-Analysis guidelines.

Results:
Five studies (N = 155,146 participants) met the inclusion criteria. While results were
mixed, our synthesis suggested an overall positive association between high trait-anger/hostility
and an increased risk of incident diabetes. Only one study met the criteria for the diabetes-related
complications outcome, which demonstrated a positive association between hostility and incident
coronary heart disease but no significant association between hostility and incident stroke.

Conclusion:
Based on the available longitudinal evidence, trait anger and hostility are associated
with an increased risk of diabetes. Longitudinal studies are needed to investigate the association
between trait-anger or hostility and the risk of diabetes-related complications.
Legal Regime for the Enforcement of Foreign Court Judgments and Arbitral Awards in the Eurasian Economic Union
Authors: Kurochkina E. M. 
Published: March 2022

In today’s world, there is intense competition between integration entities that are working to strengthen and expand their political and economic positions. This article examines the movement of the Eurasian Economic Union in this direction. Aim. To propose a way to ensure a common legal space in the Eurasian Economic Union.Tasks. To analyse the regulation in force in the Eurasian Economic Union on the execution of court judgments and arbitral awards, to identify problems that member states of the Eurasian Economic Union may encounter in the execution of court judgments and arbitral awards.Methods. In this work were used both general scientific methods of knowledge: analysis, synthesis, generalization, and particular scientific methods: formal-logical, formal-legal, comparative-legal, method of legal prediction.Results. One of the most acute problems faced by states in the execution of judicial and arbitral decisions is the problem of execution of annulled judicial or arbitral decisions. To prevent this problem within the European Economic Union, the author considers that the members of the European Economic Union should not accede to the Convention on the Recognition and Enforcement of Foreign Judgements in Civil or Commercial Matters of 2 July 2019, as it does not resolve the fate of annulled judgements. With regard to arbitral awards, it would be desirable for the Member States of the European Economic Union to conclude between themselves a protocol to the Convention on the Recognition and Enforcement of Arbitral Awards of 10 June 1958, which would exclude the enforceability of annulled arbitral awards in all the States parties to the Protocol. The drafting of this additional protocol could be entrusted to the Eurasian Economic Commission of the European Economic Union.Conclusions. The Eurasian Economic Union needs to create a predictable legal space, which would primarily be ensured by the free movement of judicial and arbitral decisions.
Pengetahuan dan Persepsi Masyarakat Terhadap Konflik Gajah Sumatera di Desa Lubuk Mandarsah
Authors: Ginda Ginda Bahari , Syarifuddin Hutwan , Hamzah Hamzah 
Published: March 2022

The condition of the Bukit Tigapuluh National Park, which is directly adjacent to agricultural land and residential areas of the Lubuk Mandarsah Village community as well as the existence of a concession permit causes a high potential for conflict between Sumatran elephants and the community. The decline in biodiversity due to overexploitation of natural resources, the conversion of company land around the Bukit Tigapuluh National Park has a negative impact on the conservation of Sumatran elephants and the survival of the people living around the buffer area of ​​the Bukit Tigapuluh National Park. With this problem, it will certainly cause conflict between humans and Sumatran elephants. The purpose of this study was to determine the knowledge and perceptions of the community towards conflicts with Sumatran elephants. This research is research using mixed method or mix method, which combines qualitative and quantitative methods. Based on this research, it was found that the level of community knowledge in the hamlet of Lubuk Mandarsah Village regarding Sumatran Elephants was classified as high (39-48) with a percentage of 82% and the perception of people in Lubuk Mandarsah Village regarding Sumatran elephants was classified as bad with a percentage of 78%.
Key words: knowledge, perception, public, Sumatran Elephant

Abstrak. Kondisi Taman Nasionnal Bukit Tigapuluh yang berbatasan langsung dengan lahan pertanian dan pemukiman masyarakat Desa Lubuk Mandarsah serta adanya perizinan konsesi menyebabkan tingginya potensi konflik gajah sumatera dengan masyarakat. Penurunan keanekaragaman hayati akibat eksploitasi sumber daya alam yang berlebihan, konversi lahan perusahaan sekitar Taman Nasional Bukit Tigapuluh menimbulkan dampak negatif terhadap konservasi gajah sumatera dan keberlangsungan hidup masyarakat yang hidup disekitar daerah penyangga Taman Nasional Bukit Tigapuluh. Dengan adanya permaslaahan ini tentu akan menimbulkan konflik antara manusia dan gajah sumatera. Adapun tujuan dari penelitian ini adalah mengetahui pengetahuan dan persepsi dari masyarakat terhadap konflik dengan gajah sumatera. Penelitian ini merupakan penelitian menggunakan metode campuran atan mix method dimana mengkombinasikan metode Kualitatif dan kuantitatif. Berdasarkan penelitian ini dihasilkan bahwa Tingkat Pengetahuan Masyarakat di dusun Desa Lubuk Mandarsah terkait Gajah Sumatera sudah tergolong Tinggi (39-48) dengan persentase sebesar 82 % dan persepsi masyarakat di Desa Lubuk Mandarsah terkait gajah sumatera masik tergolong tidak baik dengan persentase 78%.
Kata kunci: Pengetahuan, Persepsi, Masyarakat, Gajah Sumatera
Studi Literature Review: Faktor-Faktor yang Mempengaruhi Food Choice Pada Remaja Pasca Pandemik COVID-19
Authors: Pua Amaizing Evangelin , Renyoet Brigitte Sarah 
Published: March 2022

Dunia dilanda wabah virus yang disebut dengan COVID-19 hingga saat ini masih menjadi fokus utama masalah kesehatan yang perlu diselesaikan dari setiap negara di belahan dunia. Masalah kesehatan yang terjadi mempengaruhi Food choice pada setiap kalangan usia tak terkecuali pada remaja. Tujuan penulisan artikel ilmiah ini ialah untuk mengkaji faktor terkait yang mempengaruhi food choice pada remaja pasca pandemik COVID-19. Metode yang digunakan pada penulisan penelitian ini adalah study literature review, yang menganalisis dan mengumpulkan artikel-artikel penelitian mengenai faktor food choice pada remaja pasca pandemik COVID-19. Kebanyakan remaja telah mampu memilih makanan apa yang ingin di konsumsi, berbeda dengan masa kanak-kanak yang perlu dibimbing orang tuanya dalam mengkonsumsi makanan. Terdapat perubahan keputusan remaja dalam mengkonsumsi makanan yang sehat dan tidak sehat di masa pandemik COVID-19, hal ini di pengaruhi oleh beberapa faktor diantaranya ialah media periklanan di media sosial, harga produk pangan, jangkauan terhadap pangan yang terbatas, rasa bosan dan kesadaran remaja terhadap gaya hidup sehat. Dimasa pandemik ini terjadi perubahan pemilihan makanan terhadap remaja, terlihat dari banyaknya faktor yang mempengaruhi food choice pada remaja pasca pandemik COVID-19 yaitu faktor pengetahuan dan kesadaran remaja, ketersediaan pangan di masa lock-down, media sosial dan faktor emosional pada remaja.
Reporte de casos sobre el uso de ácido tranexámico para reducir el sangrado perioperatorio en liposucción y abdominoplastia
Authors: Fuentes Alzate Juan José , Fuentes Torrado Edgard Augusto , Alzate Granados Juan Pablo 
Published: March 2022

Introducción: La liposucción y la abdominoplastia son dos de las cirugías estéticas más realizadas en el mundo. Una de las complicaciones más frecuentes de estos procedimientos es el sangrado perioperatorio, el cual puede conllevar a postoperatorios inadecuados y con mayores complicaciones. Por esta razón, se deben buscar nuevos métodos que permitan reducir las pérdidas sanguíneas en este tipo de cirugías.
Objetivo: Evaluar la efectividad del ácido tranexámico en reducir el sangrado perioperatorio en liposucción y abdominoplastia.
Materiales y métodos: Estudio retrospectivo consistente en un reporte de serie de casos en el que se mencionan un grupo de pacientes a las cuales se aplicó 1 gramo de ácido tranexámico previo a la realización de liposucción y abdominoplastia. En estas pacientes se revisó un hemograma pre quirúrgico y otro post quirúrgico y se comparó la disminución de la hemoglobina y hematocrito. Así mismo, se revisó si las pacientes presentaron la necesidad de transfusión de componentes sanguíneos.
Resultados: Se obtuvo una población de 37 pacientes femeninas. Ninguna de las pacientes presentó una hemoglobina postquirúrgica menor de 8 g/dl ni requirió transfusión de hemoderivados después de la cirugía. Se realizó una correlación de Spearman entre las variables, en las cuales no se evidenció asociación entre el lipoaspirado y la hemoglobina o hematocrito postoperatorio.
Conclusión: El ácido tranexámico es un medicamento que puede ser útil para reducir el sangrado perioperatorio en liposucción y abdominoplastia ya que ninguna de las pacientes que recibió este medicamento requirió transfusión de hemoderivados.
Palabras clave: Ácido tranexámico, liposucción, abdominoplastia, hemorragia
Investigating the satisfaction of inpatients from quality of services provided by nurses and physicians in Sina hospital
Authors: Esmailpour Hassan , Bolhasani Masoumeh Asadi 
Published: March 2022

Today, most organizations by selecting customer satisfaction index as a key criterion, by assessing the quality of their services are seeking to improve customer satisfaction and therefore their survival. The quality of tool services is to determine the gaps between the considered levels and actual performance levels in a service organization or service part of a manufacturing organization. Methodology: One of the tools to check the quality of services is SERVQUAL model that by this model, dimensions of service quality including reliability, responsibility, assurance, empathy, physical dimension, and appearances of providing services is investigated. Results: The main objective of this study is to investigate the satisfaction of patient from the quality of services provided in internal sectors, surgery and special of Sina hospital. Conclusion: Also in this study, the gap between patients' expectations from the quality of services provided and the quality of services received was measured.
The Relationships between Leadership Styles and Spiritual Intelligence among School Principles
Authors: Ahmadi Sedighe , Kheirkhah Smaiel 
Published: March 2022

In the present descriptive-correlational study, the relationships between leadership styles and spiritual intelligence were studied among a group of school principals. Methodology: The population included all school principals working in Tehran’s fourth educational district throughout the school year 2011-2012. Out of the whole population, 156 subjects were selected through stratified random sampling method. Data were collected by means of ‘the Spiritual Intelligence Questionnaire’ (Sohrabi & Naseri, 2007) and ‘the Multifactor Leadership Questionnaire’ (Bass & Avolio, 2000) and analyzed through multiple regression analysis and Cronbach’s alpha coefficient. Results: The results indicated positive significant relationships between transactional and transformational leadership styles and spiritual intelligence and that transcendental self-consciousness alone can predict almost %36.2 and %14.6 of variations in transformational and transactional leadership styles respectively. Conclusion: Moreover, a significant relationship was observed between the non-interference leadership style and spiritual intelligence so that %2.9 of variations in this style could be predicted by self-consciousness and %3.2 by patients.
The Need of Dental Insurance Plan in India-Survey
Authors: Saurabh Ingole  , Vaishnavi Adhav  , Prinshu Gupta  , Vanisree Ramanathan  , Shruti Mahajan  
Published: March 2022

INTRODUCTION: Practically in every developed country, dental insurance is available to a large number of people. It reimburses a percentage of dental visits and other dental treatment providers. Dental hygiene is an essential component of our daily lives. In most industrialized nations, dental insurance is one of the most common type of medical insurance, but not in India. Dental insurance shields consumers from the financial strains that come with unexpected dental expenses. If dental insurance were available, more people would seek dental care, reducing the hardening of dental disease and future costs for expensive dental treatment. If and when dental insurance is provided, it will have a favorable influence on people's attitudes toward dental care. The availability of dental insurance will help to improve oral health. Dental insurance will encourage patients to take better care of their teeth, resulting in improved oral health. AIM AND OBJECTIVES: To formulate & introduce a comprehensive dental insurance plan in India. To evaluate people’s & dentist’s view on need of dental insurance in India. MATERIALS AND METHOD: Online questionnaire based, cross sectional study, conducted between 1st January 2022 to 30th January 2022, data was collected by filling the online questionnaire form from dentists & patients. RESULT: There is demand & need for comprehensive dental insurance plan in India. CONCLUSION: Government should provide dental insurance as part of general health care insurance to promote oral hygiene and dental field, also leading to control of the oral disease burden in India.
An Investigation of the Relationship between Workaholism and Organizational Commitment of Primary School Teachers
Authors: Özdemir Murat , Kalaycı Türk Yasemin , Sümer Sabahattin , Aypay Ahmet 
Published: March 2022

Purpose: The individuals’ workaholic tendencies are assumed to be reflected in their attitudes and behaviours in the workplace. Thus, the present study aimed to reveal the relationship between the workaholic tendencies of primary school teachers and their organizational commitment.
Design/Methodology/Approach: A correlational survey model, among the quantitative research methodologies, was adopted in the study. The research sample consisted of 301 primary school teachers working in public primary schools in a metropolitan municipality city center in southeast Turkey. The research data were collected through the Organizational Commitment Scale and the Workaholism Battery.
Findings: Affective commitment scores of the participating teachers are partially high while the normative commitment and continuance commitment scores are neutral. Regarding workaholism tendencies, e teachers have a high level of perception for enjoyment and work involvement through their drive perceptions are moderately high. Male teachers and those between 20-25 have higher workaholic tendencies of 38.9% grand total. The sub-dimensions of enjoyment and drive significantly predict affective and normative commitment while the work involvement sub-dimension of workaholism predicts continuance commitment.
Implications/Originality/Value: The effects of workaholism should be considered for future practices and research aimed at teacher commitment to be carried out in educational settings.
Perbandingan Efektivitas Ekstrak Etanolik Umbi Kembang Sungsang (Gloriosa superba L.) dan Daun Tapak Dara (Catharanthus roseus) sebagai Subtitusi Kolkisin dalam Menciptakan Poliploidi Bawang Merah (Allium ascalonicum L.)
Authors: Ainurrohmah Cicik , Isnawati Isnawati 
Published: March 2022

Peningkatan produktivitas bawang merah dapat dilakukan dengan cara poliploidi, menggunakan kolkisin. Namun kolkisin sekarang sulit ditemukan, sehingga perlu dicari anti mitotic agent alternatif. Kembang sungsang dan tapak dara adalah salah satu tanaman yang mengandung senyawa anti mitotic agent, sehingga mempunyai potensi sebagai tanaman alternatif pengganti kolkisin. Penelitian ini bertujuan untuk mengetahui pengaruh jenis mutagen, konsentrasi ekstrak, dan interaksi jenis mutagen dan konsentrasi ekstrak terhadap tingkat poliploidi bawang merah. Metode penelitian ini adalah eksperimental, dengan variabel manipulasi jenis mutagen (umbi kembang sungsang dan daun tapak dara) dan konsentrasi mutagen (0,1%, 0,2%, 0,3%), dan variabel responnya adalah tingkat poliploidi bawang merah yang dilihat dari jumlah kromosom yang dihasilkan kemudian diuji statistik dengan ANAVA dua arah dan uji DMRT. Hasilnya jenis mutagen berpengaruh terhadap tingkat poliploidi bawang merah, kolkisin adalah jenis mutagen yang paling efektif, namun ekstrak etanolik umbi kembang sungsang dan ekstrak etanolik tapak dara menunjukkan hasil tidak berbeda nyata, sehingga kedua ekstrak tersebut dapat digunakan sebagai alternatif pengganti kolkisin. Konsentrasi mutagen juga berpengaruh terhadap tingkat poliploidi bawang merah, 0,1% merupakan konsentrasi paling efektif. Interaksi jenis mutagen dan konsentrasi mutagen juga berpengaruh terhadap tingkat poliploidi bawang merah, diketahui ekstrak etanolik umbi kembang sungsang 0,1% adalah kombinasi yang paling efektif. Berdasarkan penelitian ini dapat disimpulkan bahwa jenis mutagen ekstrak etanolik kembang sungsang dengan konsentrasi 0,1% adalah interaksi yang paling efektif dalam menciptakan poliploidi bawang merah, karena dapat menghasilkan jumlah kromosom 40 = 5n yang dapat menciptakan poliploidi sekaligus meningkatkan produktivitas bawang merah.
Hubungan Morfometri Panjang, Berat, dan Diameter Tubuh dengan Organ Reproduksi Cacing Tanah Metaphire javanica
Authors: Ramadhany Tara Mayang , Budijastuti Widowati 
Published: March 2022

Cacing tanah Metaphire javanica merupakan spesies cacing tanah asli Indonesia yang memiliki peran ekologis penting dalam ekosistem tanah. Melalui kegiatan meliang, cacing tanah berperan dalam menjaga stabilitas tanah, meningkatkan laju infiltrasi dalam tanah, dan mempercepat aerasi tanah. Penelitian ini bertujuan untuk menganalisis hubungan morfometri panjang, berat, dan diameter tubuh cacing tanah Metaphire javanica dengan organ reproduksi. Sampel diambil pada enam lokasi di Kabupaten Sidoarjo, yaitu Kecamatan Taman, Kecamatan Sidoarjo, Kecamatan Wonoayu 1 dan 2, Kecamatan Gedangan, serta Kecamatan Sedati menggunakan metode purposive random sampling. Pengambilan sampel cacing tanah menggunakan metode hand sorting. Morfologi dan anatomi cacing diukur dan diidentifikasi hingga tahap tingkatan spesies kemudian dilakukan analisis korelasi PCA dengan SPSS v23. Parameter fisika dan kimia tanah yang diamati seperti suhu, pH, dan kelembapan tanah. Hasil analisis PCA menunjukkan terdapat hubungan yang erat antara panjang, berat, dan diameter tubuh dengan ukuran lubang kelamin jantan, jarak spermateka, dan ukuran lubang kelamin betina karena memiliki nilai matriks korelasi berkisar antara 0,527-0,886. Diameter tubuh dengan ukuran jarak lubang kelamin jantan memiliki nilai matriks korelasi terbesar yaitu 0,886. Sedangkan, antara panjang, berat, dan diameter tubuh dengan diameter vesikula dan diameter prostat memiliki hubungan yang lemah karena nilai matriks korelasi antara 0,033-0,420. Dengan demikian dapat disimpulkan bahwa terdapat hubungan antara morfometri panjang, berat, dan diameter tubuh dengan organ reproduksi yang meliputi ukuran jarak lubang kelamin jantan, jarak spermateka, dan ukuran lubang kelamin betina.
Rumah Listrik Berbasis STEAM untuk Meningkatkan Keterampilan Berpikir Kritis dan Hasil Belajar Era Pandemi
Authors: Yuniyati Siska 
Published: March 2022

Pandemi covid-19 membawa tantangan tersendiri dalam pelaksanaan proses pembelajaran. Kendala ditemui dalam pembelajaran materi kelistrikan. Peserta didik tidak bisa langsung berinteraksi, melakukan eksplorasi, dan konstruksi pengetahuan seperti biasa dilakukan di dalam kelas. Guru dengan segala potensi yang ada berusaha menciptakan kondisi belajar di rumah saja dan dapat mencapai tujuan pembelajaran optimal. Tujuan penelitian ini adalah untuk: 1) mendeskripsikan pembelajaran rumah listrik berbasis STEAM; 2) mengetahui peningkatan keterampilan berpikir kritis peserta didik melalui pembelajaran rumah listrik berbasis STEAM; 3) mengetahui peningkatan hasil belajar peserta didik melalui pembelajaran rumah listrik berbasis STEAM. Subjek dalam penelitian ini adalah 16 peserta didik kelas VI SD Negeri Gentan 01, Kecamatan Bendosari, Kabupaten Sukoharjo, semester I tahun pelajaran 2020/2021. Penelitian ini merupakan pengalaman terbaik pembelajaran di era pandemi covid-19. Hasil penelitian ini, yaitu: 1) deskripsi pembelajaran rumah listrik berbasis STEAM yang terbukti efektif untuk meningkatkan minat belajar, motivasi, dan keaktifan peserta didik dalam belajar di rumah; 2) Peningkatan keterampilan berpikir kritis dari skor rata-rata klasikal sebesar 38,59 meningkat menjadi 77,19 dengan kategori baik; 3) Peningkatan hasil belajar peserta didik dari rata-rata nilai klasikal sebelum diterapkan pembelajaran rumah listrik berbasis STEAM sebesar 69,06, meningkat menjadi 85, sehingga terjadi peningkatan sebesar 15,94.