Management of Acutely Symptomatic Hernia (MASH) study
Authors: Proctor Victoria K , O’Connor Olivia M , Burns Flora A , Green Susanna , Sayers Adele E , Hawkins Deborah J , Smart Neil J , Lee Matthew J ,   and the MASH Collaborators, Hoban D , Kattakayam A , Lunevicius R , Madzamba G , Rutka O , Hopley P , Ibrahim W , Issa M , Nair D , Reddington A , Wilson J , Ashmore D , Clarke R , Daniels A , Harrison L , Hope S , Masri A , Albendary M , Harris H , Pegna V , Sains P , Blencowe N S , Kirkham E , Rozwadowski S , Martin E , McFaul C , Maxwell V , Morgan J , Wilson T , Belgaumkar A , Elahi Z , Ma J , Maher S , Narayan P , Oyewole B , Adair R , Cowley J , Dobbins B , Grey T , Jackson A , Junejo M , Peter M , Saha A , Findlay A , Kakaniaris G , O’Grady H , Wilkins A , Yau J , Bhuvanakrishna T , Jeepalaya O , Sinclair M , Dunstan M , Gerogiannis I , Pelly T , Vance-Daniel J , Gurowich L , Hollyman M , Merker L , Amjad R , Barghash M , Dalmia S , Morris L , Tarazi M , Daniels S , Husnoo N , Johnston J , Denis E , Hirst C , Lim J , Patil S , Sarveswaran J , Scott L , Bondoqa I , Carter N , Darbyshire A , Moon M , Toh S , Banerjea A , Chia Z , Curtis J , Jackman J , Kanani T , Lewis-Lloyd C , Morton A , Ng J , Shaw M , Topham K , Kelleher R , Moug S , Pollock A , Westwood E , Donigiewicz U , Fowler G E , Hartrick O , Kushairi A , Massey L , Park L , Rajaretnam N , Walker E , Gupta S , Smith L , Williams G , Boland M , Damaskos D , Drogouti M , Wilson B , Lim M , Miu V , Onos L 
Published: March 2022

Abstract

Background
Acutely symptomatic abdominal wall and groin hernias are a common reason for acute surgical hospital admissions. There are limited data to guide the treatment of these patients. This study aimed to assess outcomes of emergency hernia surgery and identify common management strategies, to improve care for these high-risk patients.

Methods
A 20-week, national multicentre, collaborative, prospective cohort study (NCT04197271) recruited adults with acutely symptomatic abdominal wall and groin hernias across the UK. Data on patient characteristics, inpatient management, quality of life, complications, and wound healing were collected. Follow-up telephone calls at 30 and 90 days were used to assessed complications and quality of life. Descriptive analyses were undertaken to describe the population and outcomes.

Results
Twenty-three hospitals recruited 272 eligible patients. Inguinal (37.8 per cent) and umbilical (37.1 per cent) hernias were the most common. Some 13.9 per cent were awaiting elective surgery and 12.8 per cent had previously declined intervention. CT was performed in 47.1 per cent and 81.3 per cent underwent surgical management. Open repairs were carried out in 93.5 per cent, and 92.5 per cent of these were performed under general anaesthesia. Four of 13 laparoscopic procedures were converted to open surgery. Mesh was used in 55.1 per cent of repairs, typically synthetic non-absorbable (87.4 per cent). Complications were infrequent; surgical-site infection (9.4 per cent), delirium (3.2 per cent), and pneumonia (2.3 per cent) were the most common. The 90-day mortality rate was 4.9 per cent. Immediate surgical management was associated with a significant improvement in quality of life at 30 days (median score 0.73–0.82).

Conclusion
There is variation in the investigation, management, and surgical technique used to treat acutely symptomatic abdominal wall and groin hernias in the UK. The optimal management strategy for specific acute presentations remains to be established.
Presented to the Association of Surgeons in Training Conference, Birmingham, UK, March 2021, the Association of Surgeons of Great Britain and Ireland Congress, May 2021, the World Society of Emergency Surgery, Edinburgh, UK, September 2021, and the European Hernia Society Congress, Copenhagen, Denmark, October 2021.