bluuebunny/crossref_metadata_2025_split huggingface dataset:
Telepresence Robot Intervention to Reduce Loneliness and Social Isolation in Older Adults Living at Home (Project DOMIROB): Protocol for a Clinical Nonrandomized Study
Authors: Isabet Baptiste , Rigaud Anne-Sophie , Li Wanji , Pino Maribel 
Published: September 2022

Background
There is a growing prevalence of loneliness and social isolation among older adults (OAs). These problems are often associated with depressive states, cognitive decline, sleep disorders, addictions, and increased mortality. To limit loneliness and social isolation in OAs, some authors recommend the use of new communication technologies to maintain a social link with family members as well as with health and social care professionals. Among these communication tools, telepresence robots (TRs) seem to be a promising solution. These robots offer users the possibility of making video calls with their relatives, social workers, and health care professionals, to maintain social contact and access to support services while living at home. Nevertheless, TRs have been relatively unstudied in real-life environments.

Objective
The main objective of this study is to measure the impact of a 12-week intervention using a TR on the feeling of loneliness and on social isolation of OAs living at home. Its secondary objective is to establish recommendations for the implementation of TRs in the studied context.

Methods
A nonrandomized study will be conducted among 60 OAs living at home who will participate in the study for 24 weeks. During this period, they will host a TR for 12 weeks to use it in their home. After the end of the intervention a 12-week follow-up ensues. In total, 4 evaluations will be performed over the entire experimental phase for each participant at weeks 0, 6, 12, and 24. A multidimensional assessment of the impact of the robot will be performed using a multimethod approach including standardized scales and a semistructured interview. This assessment will also help to identify the ergonomic aspects that influence the robot’s usability and acceptability among OAs.

Results
Data collection started in September 2020 and is expected to be completed in early 2023. In August 2022, 56 participants were recruited for the study. Data analysis will take place between August 2022 and is expected to be completed in early 2023.

Conclusions
The DOMIROB study will provide new knowledge on the impact of social TRs in OAs living at home. The results will make it possible to suggest technological, ethical, and organizational recommendations for the use and implementation of TRs for OAs in real-life settings.

Trial Registration
ClinicalTrials.gov NCT04767100; https://clinicaltrials.gov/ct2/show/NCT04767100

International Registered Report Identifier (IRRID)
DERR1-10.2196/40528
Antibacterial Activity and GC–MS Based Metabolite Profiles of Indonesian Marine Bacillus
Authors: Murniasih Tutik Murniasih , P Masteria Yunovilsa , Untari  Febriana 
Published: September 2022

Investigating Indonesian marine bacteria producing active compounds is key to finding a cultivable source of marine drugs. Screening the potential strain as well as profiling the active compounds are important steps to identifying the targeted substances. Methods used in this study were isolated some Bacillus strains from several marine environments in Indonesia, evaluated the antibacterial activity, and characterized the secondary metabolite using GC-MS spectroscopy. Several active antimicrobial compounds derived from marine microorganisms were identified using GC-MS such as pyrrolo [1,2-a] pyrazine-1,4-dione, octatriacontyl pentafluoropropionate. We found that some marine bacillus showed antimicrobial activity, such as B. flexus, B. tequilensis, B subtilis, and Bacillus sp. Profiling of metabolites on GC-MS showed the presence of several bioactive compounds in the ethyl acetate extract, which were identified to be nitrogen compounds such as pyrrolo[1,2-a]pyrazine-1,4-dione, phthalates compounds (butyl isohexyl ester and 1,2 benzendicarboxilate bis (2-etilhexyl) ester), and dibutyl phthalate. Some phenolic compounds also were found, such as tris (2,4-di-ter-butilfenil) fosfat, phenol, 2,4-bis (1,1-dimethyl ethyl), and phenol 3,5-bis (1,1-dimethyl ethyl). Finally, fatty acid derivatives such as n-hexadecanoic acid, cis-vaccenic acid, 7-hexadecene, farnesol isomer A, and stigmastan-3,5-diene were also identified in several marine bacillus.
NEW HERMITE-HADAMARD TYPE INEQUALITIES FOR $k$-$\beta $-CONVEX FUNCTIONS VIA GENERALIZED $k$-FRACTIONAL CONFORMABLE INTEGRAL OPERATORS
Authors: Lakhal Fahim , Badreddine Meftah 
Published: September 2022

In this paper, we introduce a new concept $k$-$\beta $-convex functions and establish some new Hermite-Hadamard type inequalities for functions whose derivative modulus is $k$-$\beta $-convex via $k$-fractional conformable integral operators.
ON CUBIC (\alpha, \beta)-METRICS IN FINSLER GEOMETRY
Authors: Tondro Vishkaei Hosein , Tayebi Akbar 
Published: September 2022

In this paper, we study the class of cubic (\alpha, \beta)-metrics. We show that every weakly Landsberg cubic (\alpha, \beta)-metric has vanishing S-curvature. Using it, we prove that cubic (\alpha, \beta)-metric is a weakly Landsberg metric if and only if it is a Berwald metric. This yields an extension of the Matsumoto's result for Landsberg cubic metric.
VALIDNOST I POUZDANOST TESTA ZA PROCENU VREMENA REAKCIJE I BRZINE KRETANJA U ODBRAMBENOM KOŠARKAŠKOM STAVU
Authors: Vučković Igor , Gadžić Aleksandar , Sekulić Željko , Marković Saša 
Published: September 2022

The aim of the present study was to examine the content validity and reliability of the newly developed Reaction Time and Defensive Slide Test (RTADST). Thirty-six female basketball players were recruited from three professional State Basketball league of Bosnia and Herzegovina clubs (age: 18.81 ± 2.58 years) who completed three separate trials of the RTADST with each trial consisting of fast shuffling movements left and right. Each athlete performed the test 3 times in one day, and repeated testing was conducted the following day at evening basketball sessions. The RTADST relative reliability was evaluated by Cronbach’s alpha and ICC. Cronbach’s alpha coefficient was 0.81 which indicates good reliability. When recommendations from Bucheit et al. (2011) were taken into account, the value of ICC <0.69 indicated poor reliability. Absolute reliability of RTADST was assessed by CV, and its value was 5.3%, which is somewhat above the 5%, or the limit of acceptable reliability. Parameters of relative and absolute reliability after the exclusion of the first trial (familiarization with the test task), were more acceptable. Cronbach’s alpha coefficient was 0.90 and ICC = 0.82 compared to the one from all three trials. Considering absolute reliability, it could be concluded that the test is reliable since the CV value is below 5% (3.9%). Reliability between two days was assessed by ICC, and its value was 0.74, which confirms good reliability. Finally, the RTADST can be considered as a valid test that discriminates female basketball perimeter players and post players in reaction time and basketball defensive slide speed, while conditioning programs for the development of these abilities need to be carried out with a tool such is RTADST for the initial and final evaluation of these abilities.
TOURISM-LED ECONOMIC GROWTH HYPOTHESIS - AN EMPIRICAL INVESTIGATION FOR SERBIA
Authors: Hristov Stančić Branislava , Đorđević Aleksandar , Kovačević Igor , Zečević Bojan 
Published: September 2022

As it is commonly believed that tourism contributes positively to economic growth, many developing countries rely on tourism in their efforts to enhance their economic conditions. Serbia has also given priority to the development of tourism industry as a part of its economic growth strategy. In this paper we analyze the long-term effects of tourism on the economic growth of Serbia. More specifically, the tourism-led economic growth (TLEG) hypothesis is tested, which implies that tourism is a trigger of Serbian economic growth. This study investigates the causal relations between tourism growth and economic expansion for the Serbian economy by using cointegration analysis. The obtained results show that the hypothesis of tourism-led economic growth in the Serbian economy is confirmed.
ANALISIS PERENCANAAN DAN PENGANGGARAN PENDIDIKAN DI KABUPATEN SOLOK SELATAN
Authors: Sugiarto Toto 
Published: September 2022

This research is aim to identify and also evaluate document about planning and budgeting of educational in regancy South of Solok and also formulate policy, program, activity of relevant educational so that can finish problems of education in regancy South of Solok. Data is used in this research is primary data and data of sekunder. Method analysis that is: method analyze classification of problem of educational, Analyze SWOT, and Analysis Planning and Budgeting of Education in the regancy South of Solok. Result of planning document analysis (educational RPJPD, education RPJMD, RKPD, Renstra and Renja of duty Education) and analysis budgeting document (KUA and APBD) in middle and elementary educational in regancy South of Solok, not yet followed compilation order pursuant with Law number 25/ 2004, about Systems Planning of National Development.
MERANCANG PROSES PEMBELAJARAN PKN YANG MENYENANGKAN DI SMP N 4 PELEPAT ILIR
Authors: Sukarno Sukarno 
Published: September 2022

PKn Subject is the cultivication concept subject of national awareness, Pancasila, hard working attitude and responsiblity. Most of its material are concept. For giving the materials of learning, teacher have to have their own trick, so that the materials can be planned in easy by student. This research design study process which is fun for student at PKn subject. Interlude technique at learning is designed in order to support learning in the class. As a result, this research can increase the student study report.
PENERAPAN PEMBELAJARAN MATEMATIKA DENGAN PENDEKATAN KONTEKSTUAL DI KELAS X.B SMA NEGERI 1 INDRALAYA SELATAN
Authors: Wibowo Wahyu , Hartono Yusuf , Saleh Trimurti 
Published: September 2022

This research is a descriptive research that have a purpose to know description of learning math application by contextual learning approachment which is evaluated from student activity and the student study result after following math learning with contextual approachment in the X.B SMA Negeri 1 Inderalaya Selatan class. These research subjects number 25 student of X.B SMA Negeri 1 Indralaya Selatan school year 2013/2014 class. Technique of data accumulation that was done are by observation and test. The carried out data of student learning activity is collected with observation. While the test is used for knowing the student learning result after studying math by contextual approachment. As for carried out percentages of student learning activity at learning application by contextual approachment is equal to 72% that include in good category. While the percentages of efficacy student studying result mean equal to 75,48 that are categorized as a good one. So that from that assessment can be concluded that learning math application by contextual learning approachment which is evaluated from student activity and the student study result can be categorised as a good one.
Risâle-i Merâsim-i Bektaşi Adlı Esere Göre Bektaşi Nasıl İkrar Verir?
Authors: ÖĞE Mustafa 
Published: September 2022

Bektaşiliğin Babagân kolundaki en önemli törenlerden biri, kişinin miracı olarak kabul edilen ikrar erkânıdır. Bektaşi inancına göre ikrar veren nasip alır. Yani manevi sırlara vakıf olmaya başlar ve kişisel olarak olgunluğa erişinceye kadar bu içsel yolculuk devam eder.
Babagân Bektaşiliğine ait ikrar erkânlarını anlatan eserler vardır ve bunlara çatı bir isim olarak erkânnâme denir. Bu eserlerin büyük kısmı, Osmanlı döneminde Arap harfleriyle ve Türkçe kaleme alınmıştır. Çalışmanın konusu da Milli Kütüphane Yazmalar Koleksiyonunda 06 Mil Yz A 2714 yer numarasıyla kaydedilen ve ikrar erkânını anlatan Risâle-i Merâsim-i Bektâşi adlı erkânnâmedir. Tamamen İslami referanslarla kaleme alınan Risâle’-i Merâsim-i Bektâşi, mensur ağırlıklı olmak üzere mensur-manzum karışık bir eserdir.
Bu çalışmada öncelikle erkân ve erkânnâmeler hakkında kısa bilgi verilmiş ve Risâle-i Merâsim-i Bektâşi adlı eserin tanıtımı yapılmıştır. Bundan sonra Risâle-i Merâsim-i Bektâşi adlı eserin içerik analizi yapılmış ve özellikle Bektaşilik inançları açısından metin değerlendirilmiştir. Daha sonra eserin çeviri yazısı yapılmış ve en sonda da eserin orijinal metnine yer verilmiştir.
Utilization of Unconventional Water Resources (UWRs) for Aquaculture Development in Arid and Semi-Arid Regions – A Review
Authors: Soleimani-Sardo Mojtaba , Khanjani Mohammad Hossein 
Published: September 2022

Abstract
Today, the increase of the world’s population and climate change has resulted in the reduction of fresh water resources and the increase of arid and semi-arid areas, and thus, it is necessary to find a new solution to increase the production of food resources. Aquaculture is one of the sources of food production, which can play a key role in fighting poverty and hunger. Sustainable aquaculture is strongly dependent on water quantity and quality, and also, optimal fish production can be determined by the physical, chemical and biological quality of water. Due to the current restrictions and the global increase in demand for aquatic products, unconventional waters (UWs) have been used in aquaculture. UWs include: recycled water, sewage, saline water, agricultural drains and water resulting from the process of sweetening and desalination of salty water. Today, these water resources have been used to grow all kinds of aquatic animals to provide food and protein. Considering the limited water resources in the world, the use of UWs is very effective and efficient in managing drought, and is considered as one of the ways to develop food production for humans. Due to its importance in areas facing water scarcity, the use of unconventional water resources (UWRs) to supplement or replace the use of conventional fresh water sources has been considered. In this review study, the importance of UWs and their sources, aquaculture products and aquatics that can be cultivated with the help of UWs are discussed.
Black Soldier Fly Full-Fat Meal in Atlantic Salmon Nutrition – Part A: Effects on Growth Performance, Feed Utilization, Selected Nutriphysiological Traits and Production Sustainability in Fries
Authors: Mikołajczak Zuzanna , Mazurkiewicz Jan , Rawski Mateusz , Kierończyk Bartosz , Józefiak Agata , Świątkiewicz Sylwester , Józefiak Damian 
Published: September 2022

Abstract
Black soldier fly larva meal (BSFM) application as an innovative feed material has been developed in aquaculture nutrition. However, recent scientific literature is still lacking in the case of insect meal effects on different stages of salmonid fish, and the vast majority of research is focused on farmed Atlantic salmon. Therefore, the holistic approach was undertaken in the cycle of two studies carried out: on fries and pre-smolts. This study aimed to evaluate the effect of fish meal (FM) replacement by full-fat BSFM in Atlantic salmon fry diets on the growth performance, feed utilization, crude protein and crude fat digestibility, somatic indices, histomorphology of intestines, and environmental sustainability. Additionally, pellet quality was assessed. Two experiments were performed on 360 Atlantic salmon fries – each of which lasted 60 days. For the first experiment, 240 individuals were distributed to four experimental groups: six replicates (tanks) per group and 10 fish per tank. For the second experiment, 120 individuals were distributed to four experimental groups: three replicates (tanks) per group and 10 fish per tank were used. The following groups were applied: CON – without the addition of full-fat BSFM and with 39% FM; BSFM5 – with 5% addition of full-fat BSFM and 36.1% FM; BSFM10 – with 10% full-fat BSFM and 33.3% FM; BSFM15 – with 15% addition of full-fat BSFM and 30.3% FM. The present study showed satisfactory results of BSFM inclusion at the levels of 5% and 10% as a replacement for fish meal in feeds for Atlantic salmon fries. No negative effects on growth performance, feed utilization, protein and fat digestibility, or intestinal structure were recorded. Simultaneously, insect meal inclusion in Atlantic salmon diets significantly improved the environmental sustainability of the feed. In the case of BSFM15, decreases in body weight gain, protein lipid efficiency ratio, and lipid efficiency ratio, as well as increases in feed conversion ratio, were observed. Therefore, the use of shares higher than 10% of BSFM in Atlantic salmon fries may not be recommended.
Cellular and neuronal mechanisms that underlie addiction - literature review
Authors: Grzymkowska Maria , Grzywacz Elżbieta , Zadroga Łukasz , Chmielowiec Jolanta , Chwałczyńska Justyna , Błaszczak Katarzyna , Masiak Jolanta , Strońska-Pluta Aleksandra , Grzywacz Anna , Chmielowiec Krzysztof 
Published: September 2022

Abstract

Introduction: Addictive substances act on a number of neurotransmitter systems, and the end result of this action is the activation of the reward system in the brain. The cellular and neuronal mechanisms that underlie addiction have long been searched for. One of such neurotransmitters is dopamine, a catecholamine synthesized in neurons located mainly in the midbrain.

Material and method: The available literature was reviewed on the Pubmed platform and from other sources. The analysis included original studies, reviews.

The aim of the study was to review the literature on the relationship between the DRD2 gene and the occurrence of substance addiction.

Discussion: This work presents several currently discussed biological mechanisms, especially at the molecular and genetic level, involved in the process of addiction to various psychoactive substances. They discovered the brain structures that are most at risk, as well as other neurotransmitter systems and receptor proteins through which they can exert their pathological effects. It has also been established that exposure to psychoactive substances causes significant changes in expression in over 100 genes (including genes for dopaminergic, serotonergic and signaling pathways). The DRD2 receptor (present, among others, in the nucleus accumbens) plays an important role in the reward system, in the transmission of information. The weakening of this conductivity is a significant risk factor for the onset of clinical features that are associated with reward system deficiency syndrome. The expression of the D2 receptor gene may take up to 2 isoforms: short D2S and long D2L.

Conclusions: Further research at the molecular level may result in the modification of psychotherapy and pharmacotherapy in terms of their personalization.
The Economic Legacy of Mega Sporting Events. The Impact of Hosting European Olympic Games on GDP Growth Through Infrastructure Development
Authors: Zawadzki Krystian 
Published: September 2022

Abstract

Introduction.
The positive legacy of the Olympics is often cited by the International Olympic Committee and national organizers. Some scholars, however, question an uncritical approach to an exclusively positive economic legacy. The aim of this study is to evaluate the impact of hosting the Olympics on infrastructure development, with a potential impact on economic growth in the form of Gross Domestic Product (GDP) in three phases of seven Olympic Games organised in Europe in recent years.

Material and methods.
The effect of a particular Olympic period on the GDP was analysed using a difference-in-difference technique in which the difference between each of the analysed seven host countries’ GDPs and those of a reference set of countries was obtained. Each time, as part of the observation, an event time period was distinguished covering all three phases of the event: the preparatory phase, the event phase and the post-event phase.

Results.
For the Winter Olympic Games, no statistically significant positive results are observed in the long term, which may indicate a very limited importance of the economic legacy of these events for potential host countries. In the case of Summer Olympic Games, the positive impact of the organization of these events in the post-event phase is noticeable

Conclusions.
The obtained results confirm the ambiguous impact of Olympic Games on the hosts’ economies and are in line with the attitude of many scholars to an uncritical approach to the only positive legacy of these events.
The Reliability of Venous Sinus Stenosis Using Non Contrast 3D MRV in Prediction of the Diagnosis of Idiopathic Intracranial Hypertension, a Case Control Study
Authors: Fayadh Noor Abbas Hummadi , Al-Waely Noor Kathem Nee'ma , Al-Mosawe Ammar Mosa 
Published: September 2022

Abstract
Idiopathic intracranial hypertension, or shorty IIH, refers to a clinical syndrome in which there is elevated CSF pressure and papilledema in the lack of any focal neurological signs. It is largely a diagnosis of exclusion, but imaging workup is undertaken routinely in order to rule out other pathologies. In this study we tried to evaluate the prevalence of venous sinus abnormalities using the simpler and less invasive non contrast enhanced 3D TOF MRV in group of patients with IIH, using the combined stenosis score, and compare this score with a group of controls, to assess the accuracy of MRV alone as an individual test in predicting the diagnosis of IIH. The study sample included 44 patients and 25 control subjects, following MRV analysis it was found that a combined severity score of cut of value of 4.5 for the combined conduit score (CCS) was associated with 79% sensitivity and 88.6 specificity for the diagnosis of IIH, and a cut off value of 5.5 for the adjusted score method gives a 83% sensitivity and 88.6 % specificity for the diagnosis. MRV is a valuable in the diagnosis of IIH; non contrast 3D MRV is an efficient test and gives valuable diagnostic information.
Cervical intra and extramedullary hemangioblastoma with associated syringomyelia: A case report and review of the literature
Authors: Colamaria Antonio , Fochi Nicola Pio , Laguado Yasser Andres Dallos , Blagia Maria , Leone Augusto , Carbone Francesco 
Published: September 2022

Background:
Spinal hemangioblastoma (HB) is a highly vascularized tumor commonly presenting in the lower thoracic and lumbar segments. It typically causes spinal compression, extensive bleeding, and/or syringomyelia.

Case Description:
A 32-year-old female presented with persistent headaches with a cervical MRI showing an intradural and extradural mass extending from the obex to C2. Following surgical tumor resection, the patient’s symptoms resolved.

Conclusion:
Resection of spinal HB requires direct removal of the tumor mass as the accompanying cystic components typically spontaneously regress.