bluuebunny/crossref_metadata_2025_split huggingface dataset:
Post-traumatic stress disorder symptoms and associated factors in breast cancer patients during the first COVID-19 lockdown in France
Authors: Yahi Feriel , Lequesne Justine , Rigal Olivier , Morel Adeline , Leheurteur Marianne , Grellard Jean-Michel , Leconte Alexandra , Clarisse Bénédicte , Joly Florence , Lefèvre-Arbogast Sophie 
Published: September 2022

IntroductionWe aimed to study post-traumatic stress disorder (PTSD) symptoms in breast cancer (BC) patients during the coronavirus disease (COVID-19) pandemic.Materials and methodsWe included BC patients receiving medical treatment during the first COVID-19 lockdown in France. PTSD symptoms were evaluated using the Impact of Event Scale-Revised (IES-R) questionnaire. Quality of life [Functional Assessment of Cancer Therapy-General (FACT-G)], cognitive complaints [Functional Assessment of Cancer Therapy–Cognitive Function (FACT-Cog)], insomnia [Insomnia Severity Index (ISI)], and psychosocial experiences during lockdown were also evaluated. Multivariable logistic regression was used to identify clinical factors (from medical records) and psychosocial factors (from questionnaires) associated with PTSD symptoms.ResultsAmong the 253 included BC patients (mean age: 58), 46% had metastatic cancer and 52% were treated by chemotherapy alone. COVID-19-induced adjustments in medical oncology practices were experienced by 27% of patients (mainly teleconsultations). No case of COVID-19 was reported; 23% of BC patients had PTSD symptoms. Compared to other patients, patients with PTSD symptoms had more fears relative to COVID-19 infection (83 vs. 60%, p = 0.009), had more feeling of isolation (69 vs. 41%, p = 0.003), and had more prescription or increased use of psychotropic drugs (49 vs. 20%, p = 0.001). In the multivariable model adjusted for clinical factors, fears relative to COVID-19 and increased use of psychotropic drugs were independently associated with PTSD symptoms (OR [95% CI] = 3.01 [1.20–8.44] and 3.45 [1.48–8.17], respectively). Besides, patients with PTSD symptoms had poor quality of life (QoL), and more cognitive complaints and insomnia.ConclusionPost-traumatic stress disorder symptoms were observed in 23% of BC patients during the first COVID-19 lockdown in France. Psychological supports are needed for patients treated during the COVID-19 pandemic.
The career identity of young working fathers in dual-earner relationships: A family-relatedness of work decisions perspective
Authors: Crafford Anne , Koekemoer Eileen 
Published: September 2022

IntroductionTaking on an identity lens, we explore how young working fathers (in the establishment phase of their careers), experience their careers in the context of their changing family roles (shifting ideologies of fathering). We propose that working fathers’ work experiences, work decisions, and career identity are the product of social and cognitive processes in a dual-earner relationship.Materials and methodsThis qualitative study was conducted using an interpretive, and qualitative survey. The data was collected amongst a purposive sample of 45 young South African, well-educated, working fathers, using semi-structured interviews, until data saturation was reached. Interviews were recorded, transcribed, and analyzed using thematic analysis.ResultsThe three main themes extracted from the data were: “the meaning of family identity,” “the impact of family identity on career identity,” and finally, “the types of negotiation scenarios” used by working fathers in dual-earner relationships, and how they balance the work-family challenges they face.ConclusionThis study provides strong empirical support for the family-relatedness of the work decisions perspective, as we highlight the roles of working fathers as indicative of their family identities, and how these then influence their career decisions. Furthermore, our findings shed light on how dual-earner couples negotiate their work-family needs to foster positive work-family outcomes.
School-based group intervention in attention and executive functions: Intervention response and moderators
Authors: Paananen Mika , Husberg Henrik , Katajamäki Heli , Aro Tuija 
Published: September 2022

ObjectiveThis study investigated the effects of a school-based skill-training intervention in attention control and executive functions for pupils with hyperactivity-impulsivity (H-I) and cognitive control (CC) deficits. The main aim was to examine whether the intervention differently influenced H-I and CC, and whether cognitive abilities or conduct problems moderated response to the intervention.MethodElementary school pupils from 41 schools participated the study and were divided into an intervention group (n = 71) and a waitlist control group (n = 77). Intervention outcomes were assessed with an inventory assessing executive function difficulties (including H-I and CC) completed by classroom teachers.ResultsSignificant intervention effects and positive changes were detected in CC but not in H-I. Significant intervention effects were found mainly among pupils with low levels of conduct problems.ConclusionsThe results suggest that a skill-training intervention has specific positive effects on CC, but conduct problems may diminish response to intervention.
Satisfaction and associated factors among psychiatry service users at Amanuel mental specialized hospital. Addis Ababa, Ethiopia
Authors: Kibrom Esayas , Naser Zebiba , Seyoum Merga , Mengesha Atakilit , Adem Kemeria , Dechasa Deribe Bekele , Asfaw Henock 
Published: September 2022

BackgroundPatient service satisfaction is the central point for the health system. Worldwide, around 450 million people suffer from mental and behavioral disorders. Clients who are dissatisfied with the service will miss appointments, abandon the treatment plan, and eventually relapse from the illness. Despite improved access to health services, the satisfaction from health institution services was decreasing from time to time and there is little information on health service consumer satisfaction.ObjectiveTo assess the satisfaction and associated factors among psychiatric service consumers at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia, 2021/2022.Methods and materialsAn institutional-based cross-sectional study was conducted among 420 psychiatric service users from December 15 to January 16, 2021/2022. Systematic random sampling was used. A face-face interview technique and chart review were used to collect the data and a standard and validated tool called the mental health service satisfaction scale (MHSSS) was used to measure satisfaction. The collected data was entered into EPI info version 7 and exported to SPSS version 22 for analysis. The binary logistic regression model was used to analyze the data and bivariable and multivariable logistic regression analyses were conducted to identify associated factors with satisfaction. The level of significance was reported at P &lt; 0.05.ResultsThe study showed that the magnitude of patient satisfaction was 63.3% [95% CI 58.3–67.9%). Sex (AOR = 1.7, 95% CI (1.072–2.88)], educational status (AOR 4.2, 95% CI 1.64–1.8), residency [AOR = 1.8, 95% CI (1.098–3.19)], distance from the hospital [AOR 0.56, (0.34–0.93)] were significantly associated with patient satisfaction at p &lt; 0.05.ConclusionThe magnitude of patient satisfaction was high. The study showed that Sex, educational status, residence, and distance from the hospital were significantly associated with satisfaction. Prioritizing care for female patients and those coming from a distance is necessary. More ever, it is preferable to routinely and continually monitor healthcare facilities so that timely feedback can be given and problems that affect patient satisfaction can be resolved.
The effectiveness of exposure and response prevention combined with pharmacotherapy for obsessive-compulsive disorder: A systematic review and meta-analysis
Authors: Mao Lingyun , Hu Maorong , Luo Lan , Wu Yunhong , Lu Zihang , Zou Jingzhi 
Published: September 2022

ObjectiveTo systematically evaluate the effectiveness of exposure and response prevention (ERP) combined with medication on obsessive-compulsive disorder (OCD).MethodsPubMed, Web of Science, EBSCO, Cochrane, Embase, and Science Direct databases were searched to include randomized controlled trials of ERP combined with medication for OCD that met the criteria. The Yale Brown Obsessive Compulsive Scale was used as the primary outcome indicator, and Depression scales were used as secondary outcome indicators. An evaluation of bias risk was conducted to identify possible sources of bias based on methodological and clinical factors. Review Manager 5.3 and Stata 16.0 software was used to perform meta-analysis of the extracted data.ResultsA total of 21 studies with 1113 patients were included. Meta-analysis showed that ERP combined with medication therapy was significantly better than medication therapy alone including selective serotonin reuptake inhibitors, clomipramine and risperidone (MD = –6.60, 95% CI: –8.35 to –4.84, P &lt; 0.00001), but D-cycloserine (DCS) drugs do not enhance the effect of ERP intervention in patients with OCD (MD = 0.15, 95% CI: –0.87 to 1.17, P = 0.77). There is more significant maintenance by combined treatment method of medication plus ERP than medication treatment alone during the follow-up period (MD = –7.14, 95% CI: –9.17 to –5.10, P &lt; 0.00001). DCS drugs did not enhance the effect of ERP intervention on depression in patients with OCD (SMD = –0.08, 95% CI: –0.31 to 0.15, P = 0.50). ERP combined with drug improved patients’ depression levels significantly better than providing drug alone (SMD = –0.40, 95% CI: –0.68 to –0.11, P = 0.006).ConclusionPatients with OCD have significant improvement in symptoms of obsessive-compulsive disorder and depression when ERP is combined with medication, however, not enough to prove that DCS can enhance ERP effectiveness.
Strategies for screening, occupational prevention, and management of COVID-19 in outpatient clinics in Shandong
Authors: Zhang Yan , Lu Yan , Tang Juan , Sun Yu , Zhao Ze-Hua , Jian Xiang-Dong , Gao Xi-Mei 
Published: September 2022

ObjectiveWe hope to analyze the information of outpatients in a tertiary care hospital during the epidemic of COVID-19, so as to formulate effective regulations for the prevention and control of COVID-19.MethodsWe collected information from outpatients from January 28, 2020 to March 2, 2020 and performed the statistical analysis.ResultsDuring the study period, there were more than 60,000 outpatients. Among them, 404 patients with a body temperature above 37.3°C who had not been to Wuhan and had no contact with people from Wuhan. There were 8 people who had contact with people from Wuhan, such as 4 people with fever, 3 people with normal body temperature but cough symptoms, and 1 person with normal body temperature and no other discomfort. There were 2 patients with high body temperature from the epidemic area in Wuhan, and one novel Coronavirus patient was confirmed as the final result.ConclusionDuring the COVID-19 pandemic, outpatient medical staff should enhance their awareness of protection, hospitals should standardize the outpatient COVID-19 prevention and control system, improve the prevention and emergency system, and reduce occupational exposure hazards and the occurrence of post-exposure infections.
Global key concepts of civil-military cooperation for disaster management in the COVID-19 pandemic—A qualitative phenomenological scoping review
Authors: Ries Markus 
Published: September 2022

BackgroundIn the context of a holistic and comprehensive disaster response effort to the COVID-19 pandemic, many countries across the globe mobilized their military forces in order to cope with sudden and exponential surges of critically ill patients with COVID-19 in stretched healthcare systems.ObjectiveThe purpose of this work is to identify, map, and render world-wide key concepts of civil-military cooperation (CIMIC) in disaster management during the COVID-19 crisis visible.Material and methodsLiterature was systematically searched in three databases (PubMed, Web of Science, Cochrane Library) on 26 January 2022, and analyzed with qualitative, mixed narrative-phenomenological methods in compliance with PRISM-ScR and SRQR.ResultsForty-five publications were included in the analysis; pertinent authors were from 22 countries covering five continents. We identified three key thematic clusters in the published literature: Cluster (1) Medico-scientific contributions with the participation of military medical personnel or institutions: members of the military acted as subject matter experts, clinical and experimental (co-) investigators as well as co-founders for enabling COVID-19 relevant research. Areas covered were relevant to the COVID-19 patient's clinical journey from prevention, exposure, diagnostics, and treatment and included pertinent fields such as digital health and telemedicine, global and public health, critical care, emergency and disaster medicine, radiology, neurology, as well as other medical specialties, i.e., respiratory care, pulmonology, burn medicine, and transfusion medicine, in addition to environmental and occupational sciences as well as materials science. Cluster (2) CIMIC field experiences or analyses included areas such as political framework, strategy, structure, nature of civil-military interaction, and concrete mission reports in selected countries. Themes covered a broad spectrum of pandemic disaster management subjects such as capacity and surge capacity building, medical and pharmaceutical logistics, patient care under austere circumstances, SARS-CoV-2 testing support, intelligent and innovative information management, vaccination support, and disaster communication. Cluster (3) The military as a role model for crisis management.ConclusionCivil-military cooperation made a significant contribution to the level of resilience in crisis management on a global scale, positively impacting a broad spectrum of core abilities during the COVID-19 pandemic.
Establishment of a Novel Prognostic Prediction Model for Gastric Cancer Based on Necroptosis-Related Genes
Authors: Zhu Zhong-zhong , Zhang Guanglin , Liu Jianping 
Published: September 2022

Background: Necroptosis plays a crucial role in the progression of multiple types of cancer. However, the role of necroptosis in gastric cancer (GC) remains unclear. The aim of this study is to establish a necroptosis-related prediction model, which could provide information for treatment monitoring.Methods: The TCGA-STAD cohort was employed to establish a prognostic prediction signature and the GEO dataset was employed for external validation. The correlation between the risk score and the immune landscape, tumor mutational burden (TMB), microsatellite instability (MSI), as well as therapeutic responses of different therapies were analyzed.Results: We constructed a prognostic model based on necroptosis-associated genes (NAGs), and its favorable predictive ability was confirmed in an external cohort. The risk score was confirmed as an independent determinant, and a nomogram was further established for prognosis. A high score implies higher tumor immune microenvironment (TIME) scores and more significant TIME cell infiltration. High-risk patients presented with lower TMB, and low-TMB patients had worse overall survival (OS). Meanwhile, Low-risk scores are characterized by MSI-high (MSI-H), lower Tumor Immune Dysfunction and Exclusion (TIDE) score, and higher immunogenicity in immunophenoscore (IPS) analysis.Conclusion: The developed NAG score provides a novel and effective method for predicting the outcome of GC as well as potential targets for further research.
Peculiarities of Therapy of Arterial Hypertension During COVID-19 Pandemic
Authors: Бова А.А. 
Published: September 2022

Статья посвящена особенностям течения коронавирусной инфекции у пациентов с артериальной гипертензией. Приведены новые данные о роли воспаления в генезе гипертонии. Рассмотрены современные подходы к терапии артериальных гипертензий, а также позиция международных экспертов в отношении применения блокаторов ренин-ангиотензин-альдостероновой системы у пациентов с COVID-19.
The article is devoted to the peculiarities of coronavirus infection in patients with arterial hypertension. New data on the role of inflammation in the genesis of hypertension are given. Modern approaches to the therapy of arterial hypertension are considered, as well as the position of international experts regarding the use of renin-angiotensin-aldosterone system blockers in patients with COVID-19.
Correction of Cardiovascular Risk Factors in Patients with Arterial Hypertension and Diabetes Mellitus in a Time of COVID-19 Pandemic
Authors: Громова Ю.М. , Бова А.А. 
Published: September 2022

В статье рассмотрены современные подходы к терапии артериальной гипертензии у пациентов с сахарным диабетом, приведены результаты исследований влияния основных групп антигипертензивных препаратов на риск инфицирования SARS-CoV-2 и течение инфекции. Особое внимание уделено вопросам стратификации и коррекции сердечно-сосудистого риска при сахарном диабете, безопасности применения статинов у пациентов с COVID-19 и роли фиксированных комбинаций в повышении приверженности лечению для снижения сердечно-сосудистого риска в период пандемии.
The article considers modern approaches to the therapy of arterial hypertension in patients with diabetes mellitus, presents the results of studies of the influence of the main groups of antihypertensive drugs on the risk of SARS-CoV-2 infection and the severity of the course of COVID-19. Particular attention is paid to the stratification and correction of cardiovascular risk in diabetics, the safety of statins in patients with COVID-19 and the role of fixed combinations in increasing adherence to treatment to reduce cardiovascular risk during a pandemic.
Comorbidity: Cardiorenal Relationship
Authors: Мацкевич С.А. , Кожанова И.Н. 
Published: September 2022

Одним из частых проявлений коморбидности является сочетание кардиальной и ренальной патологий. Коморбидность затрудняет диагностику и фармакотерапию заболеваний. Считается, что даже незначительное почечное повреждение ассоциируется с высокой общей и кардиоваскулярной летальностью. В обзоре освещены вопросы взаимосвязи и прогностической роли ренальной и кардиальной патологии.
One of the frequent manifestations of comorbidity is a combination of cardiac and renal pathologies. Comorbidity complicates the diagnosis and pharmacotherapy of diseases. Even minor kidney damage is associated with high overall and cardiovascular mortality. The review highlights the relationship and prognostic role of renal and cardiac pathology.
UJI PERTUMBUHAN DAN PRODUKSI VARIETAS SAWI (BRASSICA CHINENSIS. L) PADA BERBAGAI SISTEM HIDROPONIK
Authors: Siregar Rizky Jui Tamara , Fitria Eka , Chairuddin Chairuddin 
Published: September 2022

Penelitian ini bertujuan untuk mengetahui respon pertumbuhan varietas sawi terhadap beberapa sistem hidroponik. Penelitian ini dilaksanakan di lahan Tagrimart BPTP Aceh pada bulan Oktober sampai bulan November. Penelitian ini menggunakan rancangan petak terpisah (split plot design) dalam Rancangan Acak Lengkap (RAL) faktorial terdiri dari dua faktor (3x3) masing masing diulang 3 kali. yaitu faktor pertama sebagai petak utama adalah sistem hidroponik dengan taraf H1 = Sistem Datar, H2 = Sistem DFT, H3 = Sistem Bertingkat, (H1 dan H3 = sistem NFT), dan anak petak yaitu Varietas dengan taraf V1 sawi pakcoy, V2 sawi caisim, V3 sawi hijau, yang diulang sebanyak 3 kali sehingga terdapat 27 unit. Hasil penelitian menunjukkan bahwa perlakuan sistem hidroponik berpengaruh nyata terhadap rata rata tinggi tanaman umur 7 HST, berpengaruh sangat nyata terhadap rata rata jumlah daun umur 21 HST. Pada perlakuan varietas berpengaruh sangat nyata terhadap rata rata tinggi tanaman umur 21 HST, jumlah daun umur 7 dan 14 HST, berat daun pertanaman dan berat basah per tanaman. Keywords : varietas; sistem hidroponik; produksi; sawi.
Pengaturan Waktu Penyerbukan dan Kuantitas Serbuk Sari terhadap Produksi dan Mutu Fisiologis Benih Labu Kuning
Authors: Haerani Nining , Herwati Andi 
Published: September 2022

Potensi hasil suatu varietas unggul salah satunya ditentukan oleh kualitas benih yang digunakan. Untuk menghasilkan produk hortikultura yang bermutu prima dibutuhkan benih bermutu tinggi, yaitu benih yang mampu mengekspresikan sifat-sifat unggul dari varietas yang diwakilinya. Penelitian ini bertujuan untuk mengetahui pengaruh waktu penyerbukan, kuantitas serbuk sari dan interaksi antara waktu penyerbukan dan kuantitas serbuk sari pada produksi dan mutu fisiologis benih labu kuning yang baik. Penelitian ini dilaksanaan di Desa Talamangape dan di laboratorium pengujian mutu benih UPTD Balai Pengawasan dan Sertifikasi Benih Tanaman Pangan dan Hortikultura di Kabupaten Maros yang berlangsung pada bulan Maret sampai Juni 2020. Penelitian ini menggunakan Rancangan Faktorial dua faktor dalam RAK dengan 9 kombinasi perlakuan yang terdiri dari 3 ulangan. Berdasarkan hasil penelitian menunjukkan bahwa pengaruh waktu penyerbukan pukul 06.00-07.00 dan kuantitas 100 % serbuk sari pada produksi dan mutu fisiologis benih labu kuning memberikan hasil terbaik pada jumlah biji perbuah, jumlah biji pertanaman, berat biji pertanaman, kecepatan berkecambah dan persentase daya kecambah Pengaruh 100% serbuk sari pada produksi benih labu memberikan hasil terbaik pada jumlah buah pertanaman, jumlah biji perbuah, jumlah biji pertanaman dan berat biji pertanaman. Terdapat interaksi antara penyerbukan pukul 06.00-07.00 dengan 50% serbuk sari yang dapat meningkat jumlah dan berat biji labu per tanaman.
PENGARUH PEMBERIAN KOMBINASI EKSTRAK DAUN MIMBA DAN WAKTU PEMBERIAN TERHADAP PERTUMBUHAN DAN PRODUKSI TANAMAN CIPLUKAN (Physalis angualata L.)
Authors: Nurca’na Nurca’na , Iinnaninengseh Iinnaninengseh , Jamal Abd. 
Published: September 2022

Ciplukan adalah Salah satu tanaman yang memiliki banyak manfaat dan khasiatnya menurut beberapa penelitian, tanaman ini yang dianggap gulma atau pengganggu budidaya tanaman yang sering digunakan oleh masyarakat sebagai penurun gula darah atau antidiabetetes, efek dari antidiabetes buah ciplukan disebabkan karena didalam tumbuhan ini memiliki kandungan kimia flavonoid. Namun pada pembudidayaan tanaman Ciplukan itu sendiri cukup rentang, dikarenakan dimasa pembuahan tanaman ciplukan pada proses pemasakan secara sempurna membuat tanaman ini mudah terserang hama, bakteri dan pathogen lainnya. Salah satu tanaman yang memiliki kemampuan untuk mengendalikan atau mengusir hama adalah dengan menunggunakan tanaman mimba (Azadirachtaindica A. Juss; Meliaceae). Penelitian ini dilaksanakan di Rea, Kecamatan Binuang, Kabupaten Polewali Mandar, Provinsi Sulawesi Barat yang berlangsung dari Bulan April sampai bulan Juli 2020. Tujuan Penelitian untuk mengetahui efektifitas tingkat keberhasilan hasil produksi dan produktivitas tanaman Ciplukan dengan pemberian ekstrak daun mimba. Penelitian ini menggunakan Rancangan Acak Kelompok dengan Pola Faktorial, terdiri dari 2 faktor yaitu Faktor pertama interval waktua plikasi yang terdiri dari 4 taraf yaitu: pada saat : umur 45 hari, umur 59 hari, umur 73 hari dan umur 87 hari. Faktor kedua pemberianekstrakdaunmimba yang terdiri dari 4 taraf yaitu : 0 ml/liter, 100 ml/liter, 200 ml/liter dan 300 ml/liter. Hasil penelitian menunjukkan bahwa interaksi kombinasi pemberian ekstrak daun mimba tidak memberikan pengaruh pada parameter pengamatan umur berbunga, daun yang rusak, buah yang rusak dan buah yang baik. Pemberian ekstrak daun mimba dengan di umur 87 hari memberikan pengaruh terbaik pada parameter pengamatan buah yang baik.