bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is pinworm infection still a public health concern among children in resource-rich region? The prevalence and time-trend analysis of pinworm infection among school-aged children in Hualien County, Taiwan: A retrospective longitudinal study
Authors: Hsiao Yu-Chao , Wang Jen-Hung , Chu Chia-Hsiang , Chang Yu-Hsun , Chang Yung-Chieh , Jan Rong-Hwa , Chu Shao-Yin , Yang Shang-Hsien , Chen Jui-Shia , Chen Ming-Chun 
Published: August 2022

Abstract
Background: Enterobius vermicularis (pinworm) is a common parasitic intestinal infection in children. A gradual decrease in prevalence of pinworm infection has been noted in resource-rich settings, such as Taiwan. However, the inﬂuence of socio-demographic factors on the temporal trend in pinworm infection rates in children under the current pinworm infection prevention policy in Taiwan is not well characterized. This study aimed to evaluate the trend of pinworm infection prevalence and the associated socio-demographic risk factors among children in Hualien County, Taiwan.Methodology: This retrospective longitudinal study included school-aged children in Hualien during 2009–2018. Children were screened for pinworm infection using adhesive cellophane perianal swabs while they were in grades 1 and 4 in school. The factors associated with pinworm infection were analyzed. Trend analysis of pinworm infection rate stratified by sex and residential setting (urban, suburban, and rural) were also performed.Results: A total of 90,730 school-aged children from grades 1 and 4 during 2009–2018 were included. Young age and male sex were risk factors for pinworm infection (P < 0.001). Negative correlation between body mass index (BMI) and enterobiasis was observed and decreased pinworm infection was noted during the study reference period. Children in suburban and rural areas had higher odds ratio for pinworm infection than those in urban areas (suburban: 1.45; rural: 5.27; P < 0.001 for both). Trend analysis revealed a significant decrease in the overall pinworm prevalence rate during 2009–2018 (P for trend: <0.001). However, there was no obvious change of pinworm infection rate in rural areas during this period (P = 0.953), and it was higher than that in urban and suburban areas.Conclusions: Risk factors for pinworm infection included young age, male, and BMI. High pinworm infection among school-age children in rural areas of Hualien is still an important issue.
SBA-15 and carbon supported nickel, heteropoly acid catalysts for the hydrodeoxygenation of lignin derived trans-Anethole to sustainable aviation fuel
Authors: Kannan Siva , Arumugam Pandurangan , Govindasamy Gopalakrishnan , arumugam pandurangan 
Published: August 2022

Abstract
Catalytic hydrodeoxygenation (HDO) of lignin derivatives is the important means of producing alkyl aromatics and cycloalkanes, key components of 100% sustainable aviation fuels (SAF). Mono and bi-functional catalysts of nickel (Ni) and heterophosphotungstic acid (HPW) supported on SBA-15 and carbons were prepared, characterized and evaluated for the HDO of lignin derived trans-anethole. The SBA-15 structure was intact but its surface area and pore volume decreased with the incorporation of Ni and HPW. UV-Visible DRS and XPS confirmed the presence of Nio and Ni2+ in the bi-functional catalysts. FTIR spectra of pyridine adsorbed Ni(10)-HPW(10)/SBA-15 catalyst has shown the presence of both Brønsted and Lewis acid (Ni2+) sites and hence its acidity was higher than mono functional HPW/SBA-15 catalyst as indicated by the ammonia TPD studies. The synergy between them might be the possible reason for the higher and stable conversion over bi-functional catalysts besides higher HDO selectivity, and more importantly selectivity for propyl benzene and propyl cyclohexane, the desired components of 100% SAF, compared to mono functional catalysts. Among the bi-functional catalysts, best catalytic performance was observed over Ni(10)-HPW(10)/SBA-15 due to its mean Ni particle size of 31.02 nm which is large enough for co-adsorption of hydrogen and benzene ring of propyl benzene may possibly be the reason for its highest selectivity to propyl cyclohexane by following the hydrogenation mechanical pathway. Optimum temperature for maximum conversion and, HDO selectivity was found to be 400oC for the bi-functional catalysts. Carbon supported Ni-HPW catalysts have shown lower selectivity for HDO, thus mesoporous SBA-15 was found to be advantageous.
Unveiling the Causal Mechanisms within Multidimensional Poverty
Authors: Grueso Hernando 
Published: August 2022

Abstract
This paper combines machine learning and econometrics to explore the relationship between multidimensional poverty components and violence in Colombia. First, I create a directed acyclic graph (DAG) using Bayesian networks and census data to predict how multidimensional poverty components are interrelated. I find that minimum living standards— measured in terms of access to water, connection to the sewage system, and the quality of walls and floors—are strong predictors of the education and health dimensions of poverty. Second, I use the DAG output to identify potential instrumental variables (IV) that may be used to test the effect of multidimensional poverty on a household’s likelihood to be a victim of violence. Illiteracy is predicted by a complex set of poverty indicators in the DAG, yet it seems to be the only connecting point between multidimensional poverty and violence showing potential to meet the validity assumptions in an IV approach. Using 2SLS, I show that having an illiterate person within a household increases by 0.4% the household’s likelihood to be a victim of violence.
Empowering Episodic Memory through a model-based Egocentric Navigational Training
Authors: Fragueiro Agustina , Tosoni Annalisa , Matteo Rosalia Di , Committeri Giorgia 
Published: August 2022

Abstract
Recent works have proposed that spatial mechanisms in the hippocampal-entorhinal system might have originally developed to represent distances and positions in the physical space and successively evolved to represent experience and memory in the mental space (Bellmund et al., 2018; Bottini and Doeller, 2020). Within this phylogenetic continuity hypothesis (Buzsáki and Moser, 2013), mechanisms supporting episodic and semantic memory would have evolved from egocentric and allocentric spatial navigation mechanisms, respectively. Recent studies have described a specific relationship between human performance in egocentric navigation and episodic memory (Committeri et al., 2020; Fragueiro et al., 2021), representing the first behavioral support to this hypothesis. Here, we tested the causal relationship among egocentric navigation and both episodic and semantic components of declarative memory. We conducted two experiments on healthy young adults: in the first experiment, participants were submitted to a navigational training, while in the second experiments participants completed a visual perceptual training. Performance in a set of memory tasks assessing episodic, semantic and short-term memory was compared among the pre- vs. post-training sessions. Results showed a specific, causal effect of the navigational training on episodic memory, as performance in this task, but not in semantic or in short-term memory tasks, was significantly improved in the post-training session. On the contrary, the visual perceptual training did not cause any improvement of the memory performance.Our findings do not only provide strong support to the phylogenetic continuity hypothesis between mechanisms of spatial navigation and memory but also offer insights for possible clinical applications.
The Association Between Infertility and Highly Educated Working Women and its Residence-Wise Prevalence: Insights from India
Authors: Singh Brijesh P. , Singh Tanya 
Published: August 2022

Abstract
Background
At the present time, after giving birth to one or two, couples usually use some method of family planning. But if women are unable to conceive a child, known as infertility, is a medical problem and carries serious demographic, social, as well as health consequences. In the present study, an attempt has been made to study the relationship between infertility and highly educated working women after controlling for certain socioeconomic and demographic variables and efforts have been made to see this difference between urban and rural residing women.
Methods
The information about infertile women is collected from 40,401 currently married women aged 20–35 in India using National Family Health Survey data conducted in 2015-16. Bivariate analysis along with unadjusted and adjusted logistic regression is used to access the relationship of our objective.
Results
Findings of the bivariate analysis revealed that among 40,401 currently married women 3782 (9.4%) women are infertile in India. Out of 3782 infertile women, 1242 (10.7%) reside in urban and 2540 (8.8%) in rural areas. Findings of logistic regression analysis show that women are 20% more likely to be infertile if they are highly educated as well as have a job. When we saw this interaction effect by place of residence, we found that women living in urban areas had a 1.32 (95% CI 1.126–1.876) times increased likelihood of infertility compared with those without this interaction effect whereas rural women had an increased likelihood of infertility by 1.06 (95% CI 1.008–1.536) times. Respondent’s age and overweight were also found to be positively associated factors of infertility in urban as well as rural areas. Although the wealth index is only a potential predictor of infertility in urban areas, its effect on infertility in rural areas is minor.
Conclusions
In India education and wealth index both are increasing day by day. Due to the increasing level of education and other knowledge in society, we observe age at marriage is also increasing particularly in the urban areas, also the intention to have less number of children in the highly educated and higher socio-economic status groups is observed, and this creates another medical burden called infertility which is an emerging issue across the world, especially in India. In fact, Infertility is not only a medical burden but also affects the married life of women. Thus, there is a need to focus on this issue and make people aware of it through various programs.
­­­­­COVID-19 vaccination responses with different vaccine platforms in patients with inborn errors of immunity
Authors: Erra Lorenzo , Uriarte Ignacio Leandro , Colado Ana , Paolini María Virginia , Seminario Gisela , Fernández Julieta , Tau Lorena , Bernatowiez Juliana , Moreira Ileana , Vishnopolska Sebastián , Rumbo Martín , Cassarino Chiara , Vijoditz Gustavo , López Ana Laura , Curciarello Renata , Rodríguez Diego , Rizzo Gastón , Ferreyra Malena , Mufarregue Leila Romina Ferreyra , Badano María Noel , Millán María Inés Pérez , Quiroga María Florencia , Baré Patricia , Ibañez Itatí , Pozner Roberto , Borge Mercedes , Docena Guillermo , Bezrodnik Liliana , Almejun María Belén 
Published: August 2022

Abstract
Patients with Inborn Errors of Immunity (IEI) in Argentina were encouraged to receive licensed Sputnik, AstraZeneca, Sinopharm, Moderna, and Pfizer vaccines, even though most of the data on available vaccines comes from trials conducted in healthy individuals. We aimed to evaluate the safety and immunogenicity of the different vaccines in IEI patients in Argentina.
The study cohort included adults and pediatric IEI patients (n=118) and age-matched healthy-controls (HC) (n=37). Samples were collected before, 28+/-3 days after the first and the second dose of the vaccine. B-cell response was evaluated by measuring IgG anti-Spike(S)/ receptor binding domain (RBD) and anti-nucleocapsid(N) antibodies by ELISA. Neutralization antibodies were also assessed with an alpha-S protein-expressing pseudo-virus assay. The T-cell response was analyzed by IFN-γ secretion on S or N-stimulated PBMC by ELISPOT and the frequency of S-specific circulating T follicular-helper cells (TFH) was evaluated by flow cytometry.
No moderate/severe vaccine-associated adverse events were observed. Regarding the antibody response, anti-S/RBD titers showed significant differences in both pediatric and adult IEI patients versus the age-matched HC cohort (p<0.05). Neutralizing antibodies were detected in 71/99 patients and were also significantly lower in the patient cohort than age-matched HC (p<0.01). Positive S-specific IFN-γ response was observed in 84.5% of IEI patients and 82.1% presented S-specific TFH cells.
In conclusion, COVID-19 vaccines showed safety in IEI patients and, although immunogenicity was lower than HC, they showed specific anti-S/RBD IgG, neutralizing antibody titers and T-cell-dependent cellular immunity with IFN-γ secreting T-cells. These findings may guide the recommendation of vaccination in IEI patients to prevent COVID-19 disease .
Origins and Distribution of Hellenistic and Late Republican Transport Amphorae in the Dalmatian Region and its Implications for Adriatic Trade and Economy
Authors: Miše Maja , Quinn Patrick Sean 
Published: August 2022

Abstract
The presence of Hellenistic and Late Republican transport amphorae at numerous sites along the Adriatic and within shipwrecks off the coast indicate that intense trade and/or exchange in commodities such as olive oil and wine took place in this region from the 4th until 1st century BC. The details of this commercial activity are nevertheless unclear in terms of the sources, destinations, and routes via which transport containers and their contents were circulated. The present study brings compositional data to bear on this topic by analysing petrographically and geochemically 248 amphorae sherds from 15 sites along the Dalmatian coast of present-day Croatia, including production sites, places of consumption and shipwrecks. This revealed the existence of several larger amphora workshops whose amphorae were used to export goods to Dalmatia during the 4th and 3rd centuries BC. They were involved in direct trade or through intermediaries in the redistribution centres. In the 2nd and 1st centuries BC, only one workshop supplied amphorae in the region, which is probably the Dalmatian town of Issa. Aspects of the regional and inter-regional distribution and redistribution of amphorae from these workshops has been reconstructed, as well as changes within the trading system over time.
Multimodal Epigenetic Sequencing Analysis (MESA) of Cell-free DNA for Non-invasive Cancer Detection
Authors: Li Wei , Li Yumei , Xu Jianfeng , Chen Chaorong , Gu Yang-kui , Lu Zhenhai , Li Diange , Li Jason , Sorg Allison , Roberts Curt , Mahajan Shivani , Gallant Maxime , Taggart David 
Published: August 2022

Abstract
Multimodal characterization of cell-free DNA (cfDNA) in blood can enable the sensitive and non-invasive detection of human cancers but remains technically challenging and costly. Here, we developed Multimodal Epigenetic Sequencing Analysis (MESA), a flexible and sensitive method of capturing and integrating multimodal epigenetic information of cfDNA using a single experimental assay, i.e., non-disruptive bisulfite-free methylation sequencing, such as Enzymatic Methyl-seq (EM-seq) and TET-assisted pyridine borane sequencing (TAPS). MESA can simultaneously infer four epigenetic modalities, namely cfDNA methylation, nucleosome occupancy, nucleosome fuzziness, and fragmentation profile for regions surrounding gene promoters and polyadenylation sites (PASs). When applied to 462 cfDNA samples from 2 independent clinical cohorts for colon cancer, new modalities (e.g., nucleosome fuzziness) and genomic features (e.g., PASs) introduced in MESA are highly complementary or superior to conventional ones, such as promoter DNA methylation, for cancer detection. Furthermore, MESA’s integrated analysis of multimodal epigenetic features significantly improved the detection accuracy for colon, liver, and pancreatic cancers compared to single modality models. Together, MESA captures additional and highly complementary epigenetic information from cfDNA without additional experimental assays, highlighting the importance and clinical potential of using multimodal epigenetic features for non-invasive cancer detection.
Study of the Curling of Tensile Test Specimens from the 6xxx Aluminum Alloy Sheet
Authors: Hwang Yeong-Maw , Chen Pao Sung 
Published: August 2022

Abstract
The 6xxx Al-Mg-Si heat-treatable alloy is lightweight, has good formability before baking-hardening, and enhanced strength after baking. The aluminum alloy is to replace steel in many automotive stamping sheet metal parts. However, under the normal hot rolling process, 6xxx aluminum alloy is prone to surface roping defects, owing to the uneven texture in the thickness direction. Aluminum with severe roping can also produce curling of the specimen in a uniaxial tensile test. The literature and related phenomena infer that the material thickness direction does not have a uniform r-value. The r-value measured by the test machine does not represent the actual whole r-value of the material. Therefore, in this paper, the actual r-values of the top and bottom surfaces of the material are derived from the geometry of the curl of the specimen. An alkali etching method is developed to layer the aluminum sheet's thickness. The layer is used for tensile testing to verify the aluminum sheet's actual r-value and derive the difference in r-value. Then, experiments and numerical simulations are used to show that the variation of thickness direction r is the leading cause of curl in the tensile specimen. Furthermore, we use numerical simulation to evaluate the difference in r-value of an aluminum sheet in each thickness layer and the effect of thickness layer on curl, and then make a reasonable explanation and correction of the difference between tensile test and simulation. Using this method, we can obtain a more accurate r-value as the material parameter for each thickness direction of an aluminum sheet, which certainly improves the accuracy of numerical simulation and analysis for other forming processes.
Insights into fundamental problems of rockburst under the modern structure stress field
Authors: Rong Hai , Li Nannan , Zhang Hongwei , Sun Dequan 
Published: August 2022

Abstract
Rockburst is one of the most severe dynamic disasters in coal mines. In this paper, the discrimination method of tectonic stress field is proposed by analyzing the Chinese modern stress field. The tectonic stress field formed by modern tectonic movement guides in-situ stress measurement. According to the stress state classification, the most rockburst coal mines in China are closely associated with tectonic stress. For the tectonic stress-driven rockburst, modern tectonic movement and modern tectonic stress field must be considered. The stress change and energy transfer caused by tectonic movement affect the geological structure where coal mines are located. Energy accumulation under rockburst conditions are mainly formed by natural geo-dynamic movement and mining configuration, and energy accumulation is the base of rockburst. The application of geo-dynamic environment evaluation method to determine the coalfield geo-dynamic process and the influence of modern tectonic movement is proposed. Accordingly, the classification method of rockburst coal mines is established. Based on the distribution characteristics of the modern tectonic condition in China, it is revealed that the dynamic disasters follow “110” distribution. Finally, a “three conditions” criterion of rockburst is proposed, namely, geo-dynamic environment is a necessary condition of rockburst, mining disturbance is a sufficient condition of rockburst, and risk-releasing measure is a controlling condition of rockburst risk mitigation.
Modeling the Forming Process by Successive Local Deforming for Monolithic Stiffened Panels
Authors: Sikulskiy Valeriy , Sikulskyi Stanislav , Maiorova Kateryna , Dyachenko Yuri 
Published: August 2022

Abstract
The study considers a method for forming stiffened monolithic panels by local deformation of the panel ribs. The local deformation is caused by bending moments along the rib towards each other. The goal of the study is to numerically model the forming process of the stiffened monolithic panel utilizing the designed local-impact tool and analyze its effects on the panel, obtaining which experimentally is challenging. The finite element method (FEM) modeling is performed in ANSYS and validated by the experimental forming of a panel made of aluminum alloy analogous to Al 2024. Simulation results provide deformation, stress, and strain distributions along the panel in loaded and unloaded states for various study cases. Furthermore, the effects of finite panel length, width, and forming process parameters such as applied force couples and single versus successive deformation are numerically investigated and discussed. Performed modeling demonstrates the advantages of the forming with the designed tool in terms of low residual stresses and their distribution. Finally, the analysis suggests future modification of the tool, particularly the shape of its grips, to minimize local residual stress concentrations.
Minimally-invasive cardiac surgery. A bibliometric analysis: A tool to identify key research and facilitate advances training
Authors: Karsan Rickesh Bharat , Allen Rhian , Powell Arfon , Beattie Gwyn William 
Published: August 2022

Abstract
Background:The number of citations an article receives is a marker of its scientific influence within a particular specialty. This bibliometric analysis intended to recognise the top 100 cited articles in Minimally-invasive Cardiac Surgery, to determine the fundamental subject areas that have borne considerable influence upon clinical practice and academic knowledge. This is increasingly relevant in a continually advancing specialty and one where minimally-invasive cardiac procedure have the potential for huge benefits to patient outcomes.Methods:The Thompson Reuters Web of Science citation index database was searched with the following terms: [Minimal* AND Invasive* AND Card* AND Surg*]. Results were limited to full text English language manuscripts and ranked by citation number. Further analysis of the top 100 cited articles was carried out according to subject, author, publication year, journal, institution and country of origin.Results:A total of 2567 eligible manuscripts were retrieved. Of the top 100 papers, the median (range) citation number was 101 (414-51). The most cited paper by Lichtenstein et al. (2006) published in Circulation with 414 citations focused on transapical transcatheter aortic valve implantation as a viable alternative to aortic valve replacement with cardiopulmonary bypass in selected patients with aortic stenosis. The Annals of Thoracic Surgery published the most papers and received the most citations (n=35; 3036). The United States of America had the most publications and citations (n=52; 5303), followed by Germany (n=27; 2598). Harvard Medical School, Boston, Massachusetts, published the most papers of all institutions. Minimally-invasive valve surgery (n=42) and coronary artery bypass surgery (n=30) were the two most frequent topics.Conclusions:This work establishes a comprehensive and informative analysis of the most influential publications in minimally-invasive cardiac surgery and outlines what constitutes a citable article. Undertaking a quantitative evaluation of the top 100 papers aids in recognising the contributions of key authors and institutions as well as guiding future efforts in this field to continually improve the quality of care offered to complex cardiac patients.Trial registration:Not applicable