bluuebunny/crossref_metadata_2025_split huggingface dataset:
Wearable Triboelectric Visual Sensors for Tactile Perception
Authors: Lu Dengjun , Liu Tao , Meng Xiangjiang , Luo Bin , Yuan Jinxia , Liu Yanhua , Zhang Song , Cai Chenchen , Gao Cong , Wang Jinlong , Wang Shuangfei , Nie Shuangxi 
Published: November 2022

AbstractTactile sensors with visible light feedback functions, such as wearable displays and electronic skin and biomedical devices, are becoming increasingly important in various fields. However, existing methods cannot meet the application requirements for the tactile perception of intensity feedback and extended intersection due to their limited light‐mapping performance and insufficient portability. Herein, a freely constructible self‐powered visual tactile sensor is proposed, which consists of a high‐output triboelectric nanogenerator (TENG) and a visual light source. The transferred charge of the TENG is enhanced to 746 nC by the structural design of the triboelectric material and device, which can easily drive the light source to generate a light signal with a brightness of 9.8 cd m−2. Notably, the application of the TENG enables to realization visual sensing of the palm‐grasp state and strength feedback without an external power supply. This visual feedback and power‐free tactile sensors are expected to have potential application in the field of artificial intelligence as a new interactive medium for smart protective clothing and robotics.
Liesegang Phenomenon of Liquid Metals on Au Film
Authors: Xing Zerong , Zhang Genpei , Ye Jiao , Zhou Zhuquan , Gao Jianye , Du Bangdeng , Yue Kai , Wang Qian , Liu Jing 
Published: November 2022

AbstractRoom temperature liquid metals (LM) such as gallium (Ga) own the potential to react with specific materials which would incubate new application categories. Here, diverse self‐organized ring patterns due to nonequilibrium reaction‐diffusion and spreading‐limitation of Ga‐based LM clusters on gold (Au) film are reported, among which diffusion is the controlling step and the self‐limiting oxide layer plays the role of kinetic barrier. Such phenomena, classically known as the Liesegang rings, mainly occur in electrolyte media. Unlike existing systems, the present periodic crystallization mechanism enables highly symmetric spatiotemporal periodic Liesegang rings on a smaller scale under ambient conditions. Typically, the Ga‐Au and eutectic gallium‐indium alloy (EGaIn)‐Au reaction‐diffusion‐spreading systems are constructed, obtaining the revert type and hybrid type concentric Liesegang patterns, respectively. The competitive patterning behavior of the intermediate phase products AuGa2 and AuIn2 in hybrid Liesegang patterns is further analyzed by altering the initial Ga/In mass ratio, first‐principles calculations, and molecular dynamic simulations. When the mass ratio of In in GaIn alloy exceeds 15%, it will preferentially react with Au. The discovery of LM Liesegang phenomenon is expected to be a flashpoint for self‐organized reaction‐diffusion systems and offers promising rules for diverse areas such as materials synthesis and the jewelry design industry.
Cascade Cross‐Coupling/Spirocyclization/Formal [4+2] Cycloaddition Reactions of 3‐(2‐Isocyanoethyl)Indoles with Aromatic Azides: Access to Polycyclic Spiroindolines Bearing A Pentasubstituted Guanidine Moiety
Authors: Gu Man‐Zhen , Deng Yan‐Qiu , Zhang Xi‐Ting , Lin Xiao‐Tong , Xu Yi‐Bing , Hu Xiao‐Wei , Liu Xin‐Ni , Zheng Yi‐Lin , Chen Guo‐Shu , Liu Yun‐Lin 
Published: November 2022

AbstractA rhodium‐catalyzed cascade cross‐coupling/spirocyclization/formal [4+2] cycloaddition reaction of 3‐(2‐isocyanoethyl)indoles with aromatic azides is developed, providing a general synthetic protocol to polycyclic spiroindolines bearing a pentasubstituted guanidine moiety with moderate to excellent yields. This transformation is highly effective since one C−C, one C=N, three C−N bonds as well as two new rings are constructed in a single step. More importantly, this work represents a new reactivity pattern of 3‐(2‐isocyanoethyl)indole, and thus constitutes an valuable addition to 3‐(2‐isocyanoethyl)indole chemistry.magnified image
Design and Synthesis of Highly Decorated Oxa‐Cage Systems via Olefin Metathesis
Authors: Kotha Sambasivarao , Keesari Ramakrishna Reddy 
Published: November 2022

AbstractHere, we report diversely fused oxa‐cages starting from various alkyl‐substituted cyclic‐ether derivatives derived via intramolecular cyclocetherification of endo‐alcohol containing endo‐norbornene derivatives. All these higher oxa‐cage systems are assembled in good to excellent yield by employing ring‐closing metathesis (RCM) or ring‐opening metathesis (ROM) as a key step. Ru‐based Grubbs catalysts (G‐I, G‐II) are effective to assemble these target molecules. In addition, a highly strained bicyclo[2.2.1]hepatane system fused oxa‐cages are easily prepared by hydrogenation sequence. Also, several highly fused saturated oxa‐cage derivatives are reported. A total of 22 examples are reported and all of these compounds are well‐characterized by NMR and HRMS data. The target compounds reported here may find significant applications in various fields of chemistry.
Impact of the Chlorination of Lithium Argyrodites on the Electrolyte/Cathode Interface in Solid‐State Batteries
Authors: Zuo Tong‐Tong , Walther Felix , Teo Jun Hao , Rueß Raffael , Wang Yubo , Rohnke Marcus , Schröder Daniel , Nazar Linda F. , Janek Jürgen 
Published: November 2022

AbstractLithium argyrodite‐type electrolytes are regarded as promising electrolytes due to their high ionic conductivity and good processability. Chemical modifications to increase ionic conductivity have already been demonstrated, but the influence of these modifications on interfacial stability remains so far unknown. In this work, we study Li6PS5Cl and Li5.5PS4.5Cl1.5 to investigate the influence of halogenation on the electrochemical decomposition of the solid electrolyte and the chemical degradation mechanism at the cathode interface in depth. Electrochemical measurements, gas analysis and time‐of‐flight secondary ion mass spectrometry indicate that the Li5.5PS4.5Cl1.5 shows pronounced electrochemical decomposition at lower potentials. The chemical reaction at higher voltages leads to more gaseous degradation products, but a lower fraction of solid oxygenated phosphorous and sulfur species. This in turn leads to a decreased interfacial resistance and thus a higher cell performance.
Non‐trivial Contribution of Carbon Hybridization in Carbon‐based Substrates to Electrocatalytic Activities in Li‐S Batteries
Authors: Zhu Jiawen , Cao Jiaqi , Cai Guolei , Zhang Jing , Zhang Wei , Xie Shuai , Wang Jinxi , Jin Hongchang , Xu Junjie , Kong Xianghua , Jin Song , Li Zhenyu , Ji Hengxing 
Published: November 2022

AbstractAppling an electrochemical catalyst is an efficient strategy for inhibiting the shuttle effect and enhancing the S utilization of Li‐S batteries. Carbon‐based materials are the most common conductive agents and catalyst supports used in Li‐S batteries, but the correlation between the diversity of hybridizations and sulfur reduction reaction (SRR) catalytic activity remains unclear. Here, by establishing two forms of carbon models, i.e., graphitic carbon (GC) and amorphous carbon (AC), we observe that the nitrogen atom doped in the GC possesses a higher local charge density and a lower Gibbs free energy towards the formation of polysulfides than in the AC. And the GC‐based electrode consistently inherits considerably enhanced SRR kinetics and superior cycling stability and rate capability in Li‐S batteries. Therefore, the function of carbon in Li‐S batteries is not only limited as conductive support but also plays an unignorable contribution to the electrocatalytic activities of SRR.
Trifluoromethylation of Carbonyl and Unactivated Olefin Derivatives by C(sp3)−C Bond Cleavage
Authors: Cong Fei , Mega Riccardo S. , Chen Jinhong , Day Craig S. , Martin Ruben 
Published: November 2022

AbstractHerein, we report a Cu‐mediated trifluoromethylation of carbonyl‐type compounds and unactivated olefins enabled by visible‐light irradiation via σ C(sp3)−C bond‐functionalization. The reaction is distinguished by its modularity, mild conditions and wide scope—even in the context of late‐stage functionalization—thus offering a complementary approach en route to valuable C(sp3)−CF3architectures from easily accessible precursors.
Wacker Oxidation von Methylencyclobutanen: Umfang und Selektivität in einer ungewöhnlichen Umgebung
Authors: Sietmann Jan , Tenberge Marius , Wahl Johannes M. 
Published: November 2022

AbstractMethylencyclobutane werden der Wacker Oxidation über eine semi‐pinakolartige Umlagerung unterzogen. Der Schlüssel zu einem erfolgreichen Prozess ist die Verwendung von tert‐Butylnitrit als Oxidationsmittel, das nicht nur eine effiziente Katalyse ermöglicht, sondern auch eine hohe Markovnikov‐Selektivität unter milden Bedingungen gewährleistet. Auf diese Weise können Cyclopentanone (26 Beispiele) in guter Ausbeute und ausgezeichneter Selektivität (bis zu 97 % Ausbeute und generell >99 : 1 Keton:Aldehyd‐Verhältnis) zugänglich gemacht werden. Die stereochemische Analyse der Reaktionssequenz zeigt ein Wanderungsverhalten, das mit verwandten 1,2‐Umlagerungen übereinstimmt. Des Weiteren können durch die Einführung eines Pyox‐Liganden an Palladium prochirale Methylencyclobutane desymmetrisiert werden, was der ersten enantioselektiven Wacker‐Oxidation entspricht.
A Liquid‐Liquid‐Solid System to Manipulate the Cascade Reaction for Highly Selective Electrosynthesis of Aldehyde
Authors: Huang Hongling , Song Xuedan , Yu Chang , Wei Qianbing , Ni Lin , Han Xiaotong , Huang Huawei , Han Yingnan , Qiu Jieshan 
Published: November 2022

AbstractElectrocatalytic synthesis of aldehydes from alcohols exhibits unique superiorities as a promising technology, in which cascade reactions are involved. However, the cascade reactions are severely limited by the low selectivity resulting from the peroxidation of aldehydes in a traditional liquid‐solid system. Herein, we report a novel liquid‐liquid‐solid system to regulate the selectivity of benzyl alcohol electrooxidation. The selectivity of benzaldehyde increases 200‐fold from 0.4 % to 80.4 % compared with the liquid‐solid system at a high current density of 136 mA cm−2, which is the highest one up to date. In the tri‐phase system, the benzaldehyde peroxidation is suppressed efficiently, with the conversion of benzaldehyde being decreased from 87.6 % to 3.8 %. The as‐produced benzaldehyde can bein situextracted to toluene phase and separated from the electrolyte to get purified benzaldehyde. This strategy provides an efficient way to efficiently enhance the selectivity of electrocatalytic cascade reactions.
PES/ZIF‐L mixed‐matrix membrane for CO2 permeation: Influence of ionic liquid in pre‐ and post‐modification treatment
Authors: Shah Buddin Meor Muhammad Hafiz , Ahmad Abdul Latif , Mohd Saufi Muhammad Amirul Asraf 
Published: November 2022

AbstractIt is known that mixed‐matrix membranes (MMMs) suffer from poor compatibility between the polymer and inorganic phases. As a result, suboptimal morphology of a membrane is obtained. This study fabricated MMMs containing ZIF‐L as the inorganic filler and polyethersulfone (PES) via the thermally induced phase separation method. ZIF‐L loading was varied from .25 to 10.0 wt% to study the effect of ZIF‐L loading on the characteristic of the MMMs and gas separation performance (CO2/N2 and CO2/CH4). Unmodified ZIF‐L resulted in significant permeability and selectivity trade‐offs. To improve the compatibility between the components and affinity towards CO2, ionic liquid (IL) was introduced. Two methods of IL modification methods were tested. They are pre‐modification of ZIF‐L and post‐modification of PES/ZIF‐L MMMs. The findings revealed that the pre‐modification method has successfully sealed the polymer/filler interfacial void compared to post‐modification. It was found that the pre‐modification method has enhanced PES/ZIF‐L membrane's performance due to the minimal interfacial defects issue at low loading; 0.75 wt% of pre‐modified ZIF‐L in the PES matrix has enhanced the permeability of CO2 by more than eight times. Furthermore, the ideal CO2/N2 and CO2/CH4 selectivity recorded at this condition is 30.1 and 21.8, respectively. On the contrary, the post‐modification strategy turns out to be counterproductive.
Physical effects of nanoaluminum oxide and nanographene on kenaf epoxy composite; vacuum bagging process
Authors: Taj Amreen , R.P Swamy , Naik Kishan , K.N Bharath 
Published: November 2022

AbstractIn this study, the effect of secondary filler nanographene and primary filler nanoaluminum oxide with kenaf epoxy was investigated. The vacuum bagging process was performed, and a magnetic stirrer was used for blending additives. Water absorption (borewell, distilled, normal, and seawater) and chemical absorption (acid, base, and neutral solution) tests were carried out to evaluate the water absorption, chemical absorption, thickness swelling, and diffusivity of the composite with varying percentages of fillers. The result demonstrates that the addition of 6% primary and 3% secondary filler together, increases the density of the sample by 13.5% and decreases void content by 77%. The addition of secondary filler lowers water absorption in normal water by 1.3% compared to other types of water, as the addition of secondary filler increases the water absorption decreases by 70% in borewell water, 75% in distilled water, 76% in normal water, and 69% in seawater. Thickness swelling of the samples decreases upon the addition of secondary fillers. In acid, the primary and secondary fillers increase the resistance to dissolution. The diffusivity rate of the sample with a combination of fillers 1.3 × 10−5.
When Molecular Dimerization Induces Magnetic Bi‐Stability at the Metal–Organic Interface
Authors: Tuerhong Rouzhaji , Ngassam Franck , Alouani Mebarek , Bucher Jean‐Pierre 
Published: November 2022

Abstract2D metal–organic frameworks have been recently proposed as a flexible platform for realizing new functional materials including quantum phases. Here, we present a method to create metal‐organic dimer complexes by on‐surface assembly on a metal substrate using low‐temperature scanning tunneling microscopy (STM) and spectroscopy (STS). We demonstrate that a dimer of Mn‐Phthalocyanine (MnPc)2 on a Ag(111) surface can be switched between two stable configurations upon a small conformational change controlled by STM manipulation. By means of density‐functional theory calculations, it is found that the two conformations correspond to an antiferromagnetic (AFM) and a ferromagnetic (FM) state respectively. Directly coordinated Mn atoms of the dimer lead to an AFM‐coupling whereas indirectly coordinated (shifted) Mn atoms lead to a FM‐coupling. Rarely seen in a molecular‐dimers with transition‐metal atoms, the FM‐AFM‐FM transition is thus readily on‐surface accessible. Furthermore, the two configurations of the switch are easily identified by their Kondo states, opening interesting routes in terms of both, writing (FM versus AFM states) and reading. These results pave the experimental route toward dimer‐based materials with complex magnetic structures of potential interest for application in spintronics, logics and computing.
Rational Design and Synthesis of D‐galactosyl Lysophospholipids as Selective Substrates and non‐ATP‐competitive Inhibitors of Phosphatidylinositol Phosphate Kinases
Authors: Sun Mengxia , Zhang Chi , Sui Dexin , Yang Canchai , Pyeon Dohun , Huang Xuefei , Hu Jian 
Published: November 2022

AbstractPhosphatidylinositol phosphate kinases (PIPKs) produce lipid signaling molecules and have been attracting increasing attention as drug targets for cancer, neurodegenerative diseases, and viral infection. Given the potential cross‐inhibition of kinases and other ATP‐utilizing enzymes by ATP‐competitive inhibitors, targeting the unique lipid substrate binding site represents a superior strategy for PIPK inhibition. Here, by taking advantage of the nearly identical stereochemistry between myo‐inositol and D‐galactose, we designed and synthesized a panel of D‐galactosyl lysophospholipids, one of which was found to be a selective substrate of phosphatidylinositol 4‐phosphate 5‐kinase. Derivatization of this compound led to the discovery of a human PIKfyve inhibitor with an apparent IC50 of 6.2 μM, which significantly potentiated the inhibitory effect of Apilimod, an ATP‐competitive PIKfyve inhibitor under clinical trials against SARS‐CoV‐2 infection and amyotrophic lateral sclerosis. Our results provide the proof of concept that D‐galactose‐based phosphoinositide mimetics can be developed into artificial substrates and new inhibitors of PIPKs.
Hybrid Hydrogen‐Bonded Organic Frameworks: Structures and Functional Applications
Authors: Liu Ying , Chang Ganggang , Zheng Fang , Chen Lihang , Yang Qiwei , Ren Qilong , Bao Zongbi 
Published: November 2022

AbstractAs a new class of porous crystalline materials, hydrogen‐bonded organic frameworks (HOFs) assembled from building blocks by hydrogen bonds have gained increasing attention. HOFs benefit from advantages including mild synthesis, easy purification, and good recyclability. However, some HOFs transform into unstable frameworks after desolvation, which hinders their further applications. Nowadays, the main challenges of developing HOFs lie in stability improvement, porosity establishment, and functionalization. Recently, more and more stable and permanently porous HOFs have been reported. Of all these design strategies, stronger charge‐assisted hydrogen bonds and coordination bonds have been proven to be effective for developing stable, porous, and functional solids called hybrid HOFs, including ionic and metallized HOFs. This Review discusses the rational design synthesis principles of hybrid HOFs and their cutting‐edge applications in selective inclusion, proton conduction, gas separation, catalysis and so forth.
Ln‐MOF Based Ratiometric Luminescent Sensor for the Detection of Potential COVID‐19 Drugs
Authors: Wang Xinrui , Batra Kamal , Clavier Gilles , Maurin Guillaume , Ding Bin , Tissot Antoine , Serre Christian 
Published: November 2022

AbstractCountless people have been affected by the COVID‐19 pandemic on a global scale. Favipiravir, has shown potential as an effective drug for SARS‐CoV‐2, attracting scientists’ attention. However, overuse of Favipiravir easily leads to serious side effects, requiring real‐time monitoring in body fluids. Given this, a new lanthanide metal‐organic framework (MOF) was prepared under solvothermal conditions from either Eu (Eu‐MOF or (1)) or Tb (Tb‐MOF or (2)) using the highly delocalized imidazoledicarboxylic acid linker H2L (H2L=5‐(4‐(imidazol‐1‐yl) phenyl) isophthalic acid) and could be successfully applied to selective optical detection of Favipiravir. In this MOF framework, the organic linker H2L provides a high excitation energy transfer efficiency that can sensitize luminescence in lanthanides. In addition, through deliberate tuning of Eu/Tb molar ratio and reaction concentration in the lanthanide framework, ratiometric recyclable luminescent EuxTb1‐x‐MOF nanoparticles with open metal sites have been constructed, which present a high detection sensitivity (Ksv=1×107 [M−1], detection limit is 4.63 nM) for Favipiravir. The detection mechanism is discussed with the help of Density Functional Theory (DFT) calculations that sheds light over the selective sensing of Favipiravir over other related COVID‐19 drug candidates. Finally, to explore the practical application of Favipiravir sensing, MOF based thin films have been used for visual detection of Favipiravir and recycled 5 times.
A Simple Nonfused Ring Electron Acceptor with a Power Conversion Efficiency Over 16%†
Authors: Wang Xiaodong , Zeng Rui , Lu Hao , Ran Guangliu , Zhang Andong , Chen Ya‐Nan , Liu Yahui , Liu Feng , Zhang Wenkai , Tang Zheng , Bo Zhishan 
Published: November 2022

Comprehensive SummaryBy simplifying the π‐bridge unit, a nonfused ring electron acceptor (NFREA) BM‐2F was designed and synthesized with several high‐yield steps. The specific molecular structure features of BM‐2F are planar molecular backbone and out‐of‐plane side chain, which is favorable for charge transport and can suppress the over‐aggregation. BM‐2F based neat and blend films display obvious face‐on molecular orientation. Specially, D18:BM‐2F based blend film can form good bicontinuous interpenetrating network. More excitingly, a power conversion efficiency of 16.15% was achieved with D18:BM‐2F based photovoltaic devices, which is the highest one based on NFREAs. Our researches manifest that NFREA is a promising direction for low‐cost and high‐performance organic solar cells.
Deep learning‐based image analysis reveals significant differences in the number and distribution of mucosal CD3 and γδ T cells between Crohn's disease and ulcerative colitis
Authors: Røyset Elin Synnøve , Sahlin Pettersen Henrik P , Xu Weili , Larbi Anis , Sandvik Arne K , Steigen Sonja E , Catalan‐Serra Ignacio , Bakke Ingunn 
Published: November 2022

AbstractColon mucosae of ulcerative colitis (UC) and Crohn's disease (CD) display differences in the number and distribution of immune cells that are difficult to assess by eye. Deep learning‐based analysis on whole slide images (WSIs) allows extraction of complex quantitative data that can be used to uncover different inflammatory patterns. We aimed to explore the distribution of CD3 and γδ T cells in colon mucosal compartments in histologically inactive and active inflammatory bowel disease. By deep learning‐based segmentation and cell detection on WSIs from a well‐defined cohort of CD (n = 37), UC (n = 58), and healthy controls (HCs, n = 33), we quantified CD3 and γδ T cells within and beneath the epithelium and in lamina propria in proximal and distal colon mucosa, defined by the Nancy histological index. We found that inactive CD had significantly fewer intraepithelial γδ T cells than inactive UC, but higher total number of CD3 cells in all compartments than UC and HCs. Disease activity was associated with a massive loss of intraepithelial γδ T cells in UC, but not in CD. The total intraepithelial number of CD3 cells remained constant regardless of disease activity in both CD and UC. There were more mucosal CD3 and γδ T cells in proximal versus distal colon. Oral corticosteroids had an impact on γδ T cell numbers, while age, gender, and disease duration did not. Relative abundance of γδ T cells in mucosa and blood did not correlate. This study reveals significant differences in the total number of CD3 and γδ T cells in particularly the epithelial area between CD, UC, and HCs, and demonstrates useful application of deep segmentation to quantify cells in mucosal compartments.