bluuebunny/crossref_metadata_2025_split huggingface dataset:
Magnitude and associated factors of anemia among adolescent girls in Ethiopia: a systematic review and meta-analysis
Authors: Berhe Kidanemaryam , Gebrearegay Freweini , Gebreegziabher Hadush , Weldegerima Lemlem , Kahsay Amaha , Hadush Haven , Gebremariam Brhane , Fseha Berhane , Gebremariam Gebrehiwot , Etsay Natnael , Hailu Micheale 
Published: August 2022

Abstract
Background
In Ethiopia, there are primary studies on adolescent anemia with imprecise and inconclusive findings. Besides, there was no meta-analysis pooled the magnitude and associated factors of anemia among adolescent girls in Ethiopia. Estimating the pooled magnitude and associated factors of anemia among adolescent girls is helpful for evidence-based interventions in Ethiopia.

Methods
The authors used a preferred reporting item for systematic reviews and meta-analysis (PRISMA). We included articles and survey reports published until May 2021 using searching engines of Google, Google Scholar, PubMed, Scopus, and Cumulative Index to Nursing and Allied Health Literature. To assess the quality of studies, we used Newcastle–Ottawa quality assessment scale for non-randomized. Two authors independently assessed the quality of the studies. We computed the pool magnitude and odds ratio of the associated factors with their 95%CI using Comprehensive Meta-Analysis software. Publication bias assessed using funnel plots and Egger’s test.

Result
In this review, we included a total of 15 studies with 9,669 adolescent girls. Using the random-effects model, the pooled magnitude of anemia among the Ethiopian adolescent girls was 19.1% (95%CI: 16.1%, 24.6%). The associated factors were attained menarche (adjusted odds ratio (AOR) = 1.96), ≥ 5 days of blood flow during menses (AOR = 6.21), food insecurity (AOR = 1.48), inadequate diet diversity score (AOR = 2.81), presence of intestinal parasite (AOR = 3.51), low body mass index (AOR = 2.49), and rural residence (AOR = 1.79).

Conclusion
The pooled magnitude of anemia among adolescent girls in Ethiopia was 19.1% depicting a mild public health problem; while attained menarche, ≥ 5 days’ blood flow during menses, food insecurity, inadequate diet diversity score, intestinal parasites, low body mass index, and rural residence were the associated factors. Hence, addressing health and nutrition wellness of adolescent girls should be center of concern in health, nutrition, agriculture, research, strategies and policies in Ethiopia.
Successful salvage of torsion testis by means of intraoperative indocyanine green fluorescence imaging
Authors: Shirasaki Yumi , Kawashima Masumi , Kimura Takuya , Yamanaka Hiroaki , Hatta Kousuke , Branch Joel , Matsuda Yasuo 
Published: August 2022

Abstract
Background
Testicular torsion (TT) is common surgical emergency that requires early diagnosis and immediate intervention within 6 h since its onset to salvage the testis. However, the decision was made only by the surgeon’s experience whether it has to be resected or not. Recently, indocyanine green (ICG) has become an excellent tool to identify biliary and vascular anatomy, and assess perfusion abnormalities in tissues. In this case report, we successfully salvaged the twisted testis, since the testicular blood perfusion was confirmed by means of intraoperative ICG (IICG) fluorescence imaging.

Case presentation
A 14-year-old healthy male patient presented due to acute left testicular pain. The patient was diagnosed with TT and had immediate surgery. Macroscopically, the testis had stagnant blood flow and appeared to be dark colored. After manual detorsion, the testis remained cyanotic and with macroscopically poor blood flow. ICG angiography was performed under near-infrared light by laparoscopic camera to assess the perfusion of the affected testicle. An excellent ICG signal appeared after 45 s in the testis, and decision was made to be preserved. Therefore, left orchidopexy was performed to complete the operation. The patient had a good postoperative course and was discharged the day after surgery. Six months later, the testis did not show any shrinkage, and both sides of the testis showed the same size without any consequences.

Conclusion
The blood flow in the testis was visually confirmed during the IICG fluorescence method. ICG fluorescence imaging may become an effective alternative to evaluate whether a testis can be preserved following TT.
COVID-somnia: anxiety, insomnia, and poor sleep among second-line healthcare workers during COVID-19 pandemic
Authors: Al-Otaibi Torki , Abbas Ahmad , Nagib Ayman Maher , Gheith Osama Ashry , Nair Prasad , Farid Mahmoud M. , Albader Mohammad A. S. 
Published: August 2022

Abstract
Background
Little information is available about the linkage between sleep affection and COVID-19. Preliminary reports and clinical observations focused on the appearance of related mental health issues, especially in healthcare workers (HCWs).

Methods
A cross-sectional study is conducted on the COVID-19 second-line HCWs using an English online survey prepared via Google forms. The survey focused on sociodemographic and profession-related characteristics (age, sex, smoking, history of previous sleep disorders or medications affecting sleep, comorbidities specialty, years of experience, and number of hours worked per week) and COVID-19-associated risks (being on the second line of COVID-19 management, following updates and news about COVID-19, and getting an infection with COVID-19 or having a colleague/friend who was infected with or died of COVID-19). Assessment of anxiety, insomnia, and sleep quality was done using the relevant diagnostic scales.

Results
This study included 162 second-line HCWs with a mean age of 34.36 ± 8.49 years. Although being in second lines, there was a high prevalence of anxiety (49.38%), insomnia (56.17%), and poor sleep quality (67.9%) during the pandemic. One condition was recently developed after the pandemic: insomnia in 6.6%, anxiety in 5.7%, and poor sleep in 16%. Two conditions were developed: insomnia and poor sleep in 21.7%, anxiety and poor sleep in 7.5%, and insomnia and anxiety in 10.4%. The three conditions were de novo experienced in 19.8%. A total of 22.4% of those who followed daily COVID-19 updates developed de novo combined anxiety, insomnia, and poor sleep. A total of 38.5% of participants that had been infected with COVID-19 developed de novo combined anxiety, insomnia, and poor sleep. A total of 50% of participants who had a colleague/friend who died with COVID-19 developed de novo combined anxiety, insomnia, and poor sleep.

Conclusion
Although being in second lines, there was a high prevalence of anxiety, depression, and poor sleep concerning COVID-19-related factors.
SRC Family Kinase Inhibition Targets YES1 and YAP1 as Primary Drivers of Lung Cancer and as Mediators of Acquired Resistance to ALK and Epidermal Growth Factor Receptor Inhibitors
Authors: Sato Hiroki , Kubota Daisuke , Qiao Huan , Jungbluth Achim , Rekhtman Natasha , Schoenfeld Adam J. , Yu Helena A. , Riely Gregory J. , Toyooka Shinichi , Lovly Christine M. , Paik Paul , Ladanyi Marc , Fan Pang-Dian 
Published: August 2022

PURPOSE The identification of novel oncogenic driver alterations and novel mechanisms of acquired resistance (AR) is the key for further development of personalized therapy. The current study investigates the potential role of YES1 amplification as a primary driver of tumorigenesis and of YES1/YAP1 amplifications as mediators of AR to ALK and epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). METHODS Models of ectopic expression were established and characterized for YES1 and YAP1 in human bronchial epithelial cells and ALK fusion–positive (ALK+) and EGFR-mutant lung adenocarcinoma cell lines. MSK-IMPACT data for all lung adenocarcinoma cases and for ALK and EGFR TKI AR cases were surveyed for YES1 and YAP1 amplification. RESULTS We report response to SRC family kinase (SFK) inhibition in a patient whose lung cancer exhibited YES1 amplification, without any well-established primary driver alteration, suggesting that YES1 amplification can also function as a primary oncogenic driver. To investigate the possibility of YES1 as a primary driver in tumorigenesis, we established preclinical models of YES1 overexpression using human bronchial epithelial cells and normal human breast epithelial cells. We showed that YES1 overexpression conferred sensitivity to SFK TKIs and promoted EGF-independent growth in a YAP1-dependent manner. Analysis of clinical genomic sequencing data from cases of AR to EGFR and ALK inhibitors revealed acquired amplification of YAP1 in four cases. EGFR-mutant and ALK fusion–positive cells overexpressing YES1 or YAP1 were resistant to EGFR and ALK TKIs, respectively, but were sensitive to dual inhibition of the primary driver and YES1. CONCLUSION Our results demonstrate the therapeutic potential of SFK inhibition in primary tumorigenesis and AR driven by YES1/YAP1 signaling.
Endocannabinoid System in the Neuroendocrine Response to Lipopolysaccharide-induced Immune Challenge
Authors: De Laurentiis Andrea , Correa Fernando , Fernandez Solari Javier 
Published: August 2022

Abstract
The endocannabinoid system plays a key role in the intersection of the nervous, endocrine, and immune systems, regulating not only their functions but also how they interplay with each other. Endogenous ligands, named endocannabinoids, are produced “on demand” to finely regulate the synthesis and secretion of hormones and neurotransmitters, as well as to regulate the production of cytokines and other proinflammatory mediators. It is well known that immune challenges, such as exposure to lipopolysaccharide, the main component of the Gram-negative bacteria cell wall, disrupt not only the hypothalamic–pituitary–adrenal axis but also affects other endocrine systems such as the hypothalamic–pituitary–gonadal axis and the release of oxytocin from the neurohypophysis. Here we explore which actors and molecular mechanisms are involved in these processes.
Controlling for What? Movements, Measures, and Meanings in the US Gender Wage Gap Debate
Authors: Hirschman Daniel 
Published: August 2022

AbstractStudies of the political power of economic knowledge have tended to foreground the role of causal claims in the form of grand theories or more narrow findings produced by experimental methods. In contrast, scholars have paid relatively little attention to the role of economic experts' descriptions. This article highlights one category of influential, quantitative descriptive claim: stylized facts. Stylized facts are simple empirical regularities in need of explanation. Focusing on the example of the gender wage gap in the United States, this article showcases how stylized facts travel into political debates, and how the choices made in characterizing an aspect of economic life (such as controlling for full-time work, but little else) interact with social movement activism, and folk understandings of economic life. The gender wage gap was first calculated in the 1950s, but did not take on special importance until the 1960s–1970s, when feminists rallied around the statistic as a useful aggregate measure of women's economic disempowerment. Academics soon followed, and sociologists and economists began to publish studies documenting trends in the gap and trying to account for its sources. The comparable worth movement of the 1980s explicitly argued that the wage gap resulted from occupational segregation and the devaluation of women's work. As that movement faltered in the late 1980s, the gender wage gap became increasingly understood through the lens of women's choices and trade-offs between work and family, and occupational segregation dropped out of the narrative. Throughout this period, the gap was frequently misunderstood or misrepresented as reflecting the narrow sort of same-job, different-pay discrimination made illegal by the 1963 Equal Pay Act, adding confusion to the public debate over women's economic position. These dynamics showcase how technical choices made in the identification of stylized facts, such as statistical controls, are simultaneously deeply political choices.
The Production of Everyday Space for Workers: The New Village Movement in China, 1919–1936
Authors: Zhu Qian 
Published: August 2022

Abstract
The idea of a “new village” first emerged in the years 1919–20 and was widely discussed by Chinese intellectuals, who advocated for its humanitarian and social justice purposes and its goal of constructing a new society. This article focuses on the new village movement in China from 1919 to 1936, which was imagined and materialized by intellectuals, social reformers, and the Nationalist state in response to crises of capital accumulation, displacement of labor, and urbanization. New villages emerged as a worldwide sociopolitical response to exploitation and class antagonism—the worst effects of capital accumulation and the alienation of labor, under which the creation of everyday spaces for labor reproduction provided the key to constructing a new type of community for social transformation among migrant workers. Whereas the state and capital attempt to “pulverize” new villages into a manageable, calculable, and abstract grid, diverse social forces simultaneously attempt to create, defend, or extend spaces of social reproduction, everyday life, and grassroots control. Thus, the new village's anti-capitalism combined an eminently modern criticism of capitalism with the conservative recovery of an ideal rural community, in an attempt to overcome social inequality and the urban exploitation of the rural caused by capital accumulation.
Low-End Accumulation: Spatial Transformation and Social Stratification in a Beijing Urban Village
Authors: Ou Tzu-Chi 
Published: August 2022

AbstractIn late 2017, a tragic fire in southern Beijing led to a massive eviction and demolition campaign that drove out tens of thousands of rural migrant workers in bleak winter weather. While the evictions were widely covered by the mass media, few analyses examined the gongyu 公寓 (apartment complex), a low-rent housing complex where the fire broke out. Based on fieldwork in Beijing's northern fringe, this article examines the spatial transformation of residences from cramped one-story farmhouses to gongyu and how it signals the social stratification of migrant tenants. The emergence of the better-equipped gongyu, as an alternative modernity, caters to the influx of young tenants and migrants working in the service sector. Meanwhile, the rise of the gongyu has propelled an increase in the subcontracting of property management. The rationalization and specialization of the fast-growing private rental housing market have further led to estranged living among migrant tenants and landlords, who experience different forms of displacement in urban villages. Gongyu is the outcome of low-end accumulation, which is intended primarily for constructing low-quality, low-cost rental projects for the “low-end population.” Despite its prevalence, the urban village gongyu represents an overlooked, unrecognized, and undesirable mode of urbanization, which is the target of the recurring housing crackdown in China's capital.
“There Will Be No Free Bohemia without Free Poland, No Free Poland without Free Bohemia”. Masaryk’s Vision of Independent States
Authors: Pavlíček Tomáš W. 
Published: August 2022

The aim of the paper is to examine, using the comparative perspective, how politicians and historians perceived the ideas applied in the process of formation of the states of Poland and Czechoslovakia. The situation in the period of 1918–20 seemed to be open to various opportunities for constituting and cooperation of independent countries, but not all these opportunities were acceptable at that time. Although some of them had a stabilising potential, the official narrative became the foundation for national historiography.
The traditional master narrative (roles of Masaryk, Dmowski, Piłsudski), interrupted by the caesura of the 1945/54–89 period, understandably affects the current understanding of a state and celebration of its anniversaries, which raises a need to find a paradigm of interpretation that deviates from the nation state. The author disputes the approach of historiography which considered military violence a defining element of the process of formation of a state. He regards choosing a perspective which explains the transfer of the traits of the founders to the states as social institutions (quasi-figures) to be beneficial. Using archival documents, he shows how Masaryk’s ideas of forming a New Europe were received in Poland and what image of the situation in Poland was presented to Masaryk. Criticism of the neighbouring state in the speeches of the members of the Sejm was instrumentalised with regard to the tensions in the home politics. That is why the author puts the dispute about the Seven-day War and the Polish-Ukrainian conflict into a broader perspective.
Why did God not Create us in Heaven? The Idea of Creation in statu viae in Thomas Aquinas and Thomas Talbott
Authors: Adamski Bartosz 
Published: August 2022

Dlaczego Bóg nie stworzył nas w niebie? Idea stworzenia in statu viae u Tomasza z Akwinu i Thomasa Talbotta
Thomas Talbott, ewangelicki profesor filozofii i uniwersalista, swoim dziele zatytułowanym The Inescapable Love of God (wyd. 1999 r.), odpowiada Michaelowi Murray’owi, który, zakładając uniwersalistyczną powszechność zbawienia, zadaje następujące pytanie: Dlaczego Bóg nie stworzył nas wszystkich ab initio w stanie ostatecznym w niebie? W artykule zostanie porównana odpowiedź Talbotta na pytanie postawione przez Murraya z nauczaniem św. Tomasza z Akwinu, który wyjaśnia, dlaczego Raj był właściwym miejscem dla ludzi przed grzechem pierworodnym. W ten sposób zostaną ukazane podobieństwa i różnice w rozumowaniu Akwinaty i Talbotta. Posłuży to do wykazania, że argumentacja Doktora Anielskiego jest wciąż użyteczna i aktualna we współczesnych debatach.
Risk factors and diagnosis of iatrogenic damage of periodontal structures and roots during orthodontic Mini-Implants implantation procedures - a systematic literature review
Authors: Nieścior Hubert , Sereda Dominika , Metelska Aleksandra , Metelski Jakub 
Published: August 2022

Introduction and purpose
In recent years, Mini-Implants (MI) have gained popularity and new complications have emerged with them. The article assesses the current reports on the scale of the problem, factors and diagnostic possibilities related to iatrogenic injuries of periodontal tissues and roots.

Description of the state of knowledge
The incidence of complications was estimated to be 13.5%. Complications are more common in the mandible and are estimated at 20-27.1%. Periodontal and root damage are an important risk factor for treatment failure. The fact that the implant does not interfere with the alveolus structure gives the treatment effectiveness in 90%, and the contact with the alveolar “lamina dura” is 62.5%. Interference with the root structure is successful in only 31.2%.
Risk factors for failure include: young age, poor hygiene, smoking, area of mandibular molars, contact with the root, thickness of the bone and lack of experience. The implant between the roots is a risk of root trauma, as the location close to the tooth cemento-enamel junction, no preparation for surgery, not using surgical templates, strenuous implantation or implant migration under the influence of orthodontic forces. Radiographs are the gold standard in the diagnosis of complications, but they do not allow for a full assessment of the three-dimensional structures of the implant. A promising method is the evaluation of the torque as the implant is placed in its final location. The patient's subjective feelings are questionable in diagnosis and require further research.
Summary
There are many complications in using MI and the most important of these is damage to the structures of the periodontium and the tooth root. Despite the low failure rate, failure should be prevented by pre-operative evaluation, in-operative monitoring, and post-operative diagnostics.
Clinical features and management of iris melanoma - a systematic review
Authors: Sereda Dominika , Nieścior Hubert , Metelska Aleksandra , Metelski Jakub 
Published: August 2022

Introduction and purpose
Uveal melanoma is the most common primary intraocular malignancy in adults. Most of them arise in the choroid and ciliary body, whereas 2-5 % of the cases are located to the iris. Nevertheless, during the last few decades the incidence of this neoplasm has been increasing. The aim of the study is to discuss the risk factors, clinical features and methods of diagnosis and treatment of iris melanoma.
Description of the state of knowledge
Iris melanomas vary in their shape, size, degree of pigmentation and clinical behavior and most commonly present as a nodular tumor located in the lower temporal iris quadrant. This localisation is linked to exposure to solar radiation, which among light-colored iris, skin color and pre- existing iris naevus, is a risk factor for this malignancy. Gender predilection for the development of iris melanoma is unclear, however, some studies indicate a predominance of female patients. The most common clinical symptoms are growth of a pre-existing naevus, detection of new, dark lesion, pain secondary to elevated IOP and blurred vision. Due to anterior location of this site of uvea, early diagnosis and treatment is possible. Slit-lamp examination, gonioscopy, and ultrasound biomicroscopy (UBM) allow staging of the tumor to guide the most appropriate treatment. As many primary iris lesions have a benign prognosis, surgical resection or radiotherapy is efficient way of treatment and allows good local tumor control.
Summary
Iris melanoma is least frequent of all uveal melanomas and usually presents as variably pigmented, elevated, solitary lesion. When there is a clinical suspicion of malignancy slit- lamp examination and UBM should be performed. When early diagnosed it can be successfully treated.
Local tolerance and quality evaluation for optical surfaces
Authors: Deng Yuting , Tan Yilin , Wu Xiaofei , Zhu Jun 
Published: August 2022

The manufacture of high-precision surfaces is the foundation of building high-performance optical systems. For over 50 years, the tolerance for optical surfaces has been specified by the root-mean-square (rms) or peak-to-valley (PV) value over the entire surface geometry. However, different regions on optical surfaces do not contribute equally to image quality and, thus, can tolerate different levels of errors. A global tolerance described by a single or few parameters cannot precisely provide the manufacturing requirements of each region on the surface, which may result in unnecessary accuracy specifications for surfaces. Furthermore, the components with the same PV or rms figure errors can produce different imaging qualities; however, this difference cannot be distinguished by the conventional figure of merit. To address these problems, a framework that includes a local tolerance model and a quality merit function for optical surfaces is proposed. The local tolerance model can provide an accurate tolerance for each region on the surface so the targeted wave aberration requirements are met during components manufacturing. More importantly, the proposed merit function closely ties the surface figure error to imaging performance, e.g., the findings can explain that the component with lower geometric accuracy may produce better imaging quality. This framework provides new insights into optical design, manufacture, and metrology and especially paves the way for the manufacture of high-precision large-aperture systems.