bluuebunny/crossref_metadata_2025_split huggingface dataset:
Liver stiffness as surrogate parameter in emergency assessment for inpatient health care utilization
Authors: Kaddu-Mulindwa Dominic , von Martial Marius , Thiel-Bodenstaff Angela , Lesan Vadim , Ewen Sebastian , Mahfoud Felix , Lammert Frank , Krawczyk Marcin 
Published: April 2022

BackgroundTransient elastography (TE) allows non-invasive quantification of liver stiffness (LSM) and steatosis (controlled attenuation parameter, CAP). Here we test the feasibility and utility of TE in the emergency department (ED) and investigate whether LSM predicts longer hospitalization and reimbursement for non-elective patients.MethodsLSM and CAP were determined in prospectively recruited consecutive adult patients admitted to the ED of a tertiary referral center. Patients were stratified according to the 9.1 kPa and 13.0 kPa LSM cut-offs. Elastography measurements were correlated with clinical and outcome parameters, including duration of hospital stay and hospitalization costs.ResultsIn 200 ED patients (133 men, age 18 – 97 years), median LSM was 5.5 kPa (2.4 – 69.1 kPa), and median CAP was 252 dB/m (100 – 400 dB/m). In total, 39 patients (19.5%) presented with LSM ≥ 9.1 kPa, and 24 patients (12.0%) presented with LSM ≥ 13.0 kPa. Heart failure (n = 19) was associated with higher LSM (p = 0.045). Patients with LSM ≥ 9.1 kPa were significantly (p < 0.01) more likely to require longer hospitalization than those with lower LSM. Patients with LSM ≥ 13.0 kPa generated significantly (p = 0.001) higher costs as compared to patients with low LSM.ConclusionsTransient elastography represents an easily accessible screening tool in ED that might help identify patients in need of increased health care resources.
Impact of covid-19 on long-term oxygen therapy 2020: A nationwide study in Sweden
Authors: Sundh Josefin , Palm Andreas , Wahlberg Josefin , Runold Michael , Ekström Magnus 
Published: April 2022

Introduction
Covid-19 can cause chronic hypoxic respiratory failure, but the impact on the need for long-term oxygen therapy (LTOT) is unknown. The aim was to investigate change in incidence and characteristics of patients starting LTOT in Sweden 2020 after the outbreak of the pandemic.

Material and methods
Population-based observational study using data from the National Registry for Respiratory Failure (Swedevox) and from a survey to all centres prescribing LTOT in Sweden. Swedevox data provided information on incidence of LTOT and characteristics of patients starting LTOT during 2015–2020.

Results
Between March-Dec 2020, 131 patients started LTOT due to covid-19, corresponding to 20.5% of incident LTOT in Sweden. Compared with 2015–19, the total number of patients starting LTOT did not increase. No significant differences in patient characteristics or underlying causes of hypoxemia were found between patients starting LTOT during 2020 compared 2015–2019. The majority of the LTOT centres estimated that, since the start of the pandemic, the incidence of LTOT was unchanged and the time devoted for LTOT work was the same or slightly less.

Conclusions
Covid-19 caused one fifth of all LTOT starts during the pandemic in 2020. The LTOT incidence overall did not increase possibly due to reduction in other infections.
Differentially expressed microRNAs during the differentiation of muscle-derived stem cells into insulin-producing cells, a promoting role of microRNA-708-5p/STK4 axis
Authors: Ren Yu , Wang Xiao , Liang Hongyu , Ma Yuzhen 
Published: April 2022

Objective
Stem cell therapy is a promising approach for diabetes via promoting the differentiation of insulin-producing cells (IPCs). This study aimed to screen the differentially expressed miRNAs (DEmiRNAs) during the differentiation of muscle-derived stem cells (MDSCs) into IPCs, and uncover the underlying function and mechanism of a specific DEmiRNA, miR-708-5p.

Methods
MDSCs were successfully isolated from the leg muscle of rats, and were induced for IPCs differentiation through a five-stage protocol. miRNA microarray assay was performed for screening DEmiRNAs during differentiation. The features of MDSCs-derived IPCs were identified by qRT-PCR, flow cytometry, and immunofluorescence staining. The targeting of STK4 by miR-708-5p was examined by luciferase assay. The protein expression of STK4, YAP1, and p-YAP1 was determined by Western blot and immunofluorescence staining.

Results
MDSCs were successfully isolated and differentiated into IPCs. A total of 12 common DEmiRNAs were obtained during five-stage differentiation. Among them, miR-708-5p that highly expressed in MDSCs-derived IPCs was selected. Overexpression of miR-708-5p upregulated some key transcription factors (Pdx1, Ngn3, Nkx2.2, Nkx6.1, Gata4, Gata6, Pax4, and Pax6) involving in IPCs differentiation, and increased insulin positive cells. In addition, STK4 was identified as the target gene of miR-708-5p. miR-708-5p overexpression downregulated the expression of STK4 and the downstream phosphorylated YAP1.

Conclusions
There were 12 DEmiRNAs involved in the differentiation of MDSCs into IPCs. miR-708-5p promoted MDSCs differentiation into IPCs probably by targeting STK4-mediated Hippo-YAP1 signaling pathway.
Reporting of diagnostic and laboratory tests by general hospitals as an indication of access to diagnostic laboratory services in Kenya
Authors: Bahati Felix , Mcknight Jacob , Swaleh Fatihiya , Malaba Rose , Karimi Lilian , Ramadhan Musa , Kiptim Peter Kibet , Okiro Emelda A. , English Mike 
Published: April 2022

Introduction
Information on laboratory test availability and current testing scope among general hospitals in Kenya is not readily available. We sought to explore the reporting trends and test availability within clinical laboratories in Kenya over a 24-months period through analysis of the laboratory data reported in the District Health Information System (DHIS2).

Methods
Monthly hospital laboratory testing data were extracted from the Kenyan DHIS2 between January 2018 and December 2019. We used the national laboratory testing summary tool (MoH 706) to identify the tests of interest among 204 general hospitals in Kenya. A local practitioner panel consisting of individuals with laboratory expertise was used to classify the tests as common and uncommon. We compared the tests on the MoH 706 template with the Essential Diagnostic List (EDL) of the World Health Organisation and further reclassified them into test categories based on the EDL for generalisability of our findings. Evaluation of the number of monthly test types reported in each facility and the largest number of tests ever reported in any of the 24 months were used to assess test availability and testing scope, respectively.

Results
Out of the 204 general hospitals assessed, 179 (179/204) reported at least one of the 80 tests of interest in any of the 24 months. Only 41% (74/179) of the reporting hospitals submitted all their monthly DHIS2 laboratory reports for the entire 24 months. The median testing capacity across the hospitals was 40% with a wide variation in testing scope from one hospital laboratory to another (% IQR: 33.8–51.9). Testing scope was inconsistent within facilities as indicated by often large monthly fluctuations in the total number of recommended and EDL tests reported. Tests of anatomical pathology and cancer were the least reported with 4 counties’ hospitals not reporting any cancer or anatomical pathology tests for the entire 24 months.

Conclusion
The current reporting of laboratory testing information in DHIS2 is poor. Monitoring access and utilisation of laboratory testing across the country would require significant improvements in consistency and coverage of routine laboratory test reporting in DHIS2. Nonetheless, the available data suggest unequal and intermittent population access to laboratory testing provided by general hospitals in Kenya.
Autoevaluación de los estudiantes en la práctica profesional de la Licenciatura en Nutrición, 2019
Authors: Ravelli Sandra , Vignatti Ayelén Urbine , Guattini Marina 
Published: April 2022

En la Práctica profesional de la Licenciatura en Nutrición, el/la estudiante asume un compromiso con el espacio curricular y con los lugares de práctica asignados, vivenciando instancias formativas en pos de su formación profesional. En ese orden es posible corresponsabilizar al estudiante en el proceso de toma de decisiones que supone la evaluación. A los fines de implementar el proceso de autoevaluación de los/las estudiantes de la práctica profesional de Licenciatura en Nutrición en las tres áreas experienciadas, en la cohorte 2019, se estudió una muestra de 33 estudiantes. Se utilizó un cuestionario, elaborado en el marco de una actividad de formación extracurricular en investigación y desarrollo. Se observó que los estudiantes valoraron el proceso, priorizando aspectos actitudinales. Adaptarse a diferentes situaciones, es la competencia más ponderada. Se revaloriza el vínculo con el tutor y ambientes formativos que propicien la autonomía en el desarrollo de futuros profesionales. A través de este aporte, se pretende revisar la asignatura, su metodología y conocer competencias transversales y disciplinares desarrolladas por los/las estudiantes.
Pertumbuhan Kacang Hijau (Vigna radiata) Setelah Perlakuan Naungan
Authors: Izzati Munifatul 
Published: April 2022

Kacang hijau (Vigna radiata) merupakan salah satu sumber pangan yang kaya nilai nutrisi. Pertumbuhan penduduk yang tinggi di Indonesia memerlukan suplai tanaman pangan yang mencukupi. Beberapa spesies kacang kacangan dapat ditingkatkan petumbuhan dan produksinya dengan perlakuan intensitas cahaya. Penurunan intensitas cahaya hingga ke level tertentu dapat berpengaruh pada pertumbuhan tanaman. Penelitian ini bertujuan untuk menganalisis pengaruh naungan terhadap pertumbuhan tanaman kacang hijau. Penelitian dilakkukan di Laboratorium Biologi Struktur dan Fungsi Tumbuhan. Kacang hijau ditanam dalam pot berdiameter 30 cm, dan tinggi 40 cm. kelompok perlakuan adalah tanaman kacang hijau yang diberi naungan paranet dgn intensitas cahaya 45%, sedangkan kelompok kontrol adalah tanaman kacang hijau tanpa naungan, dengan intensitas cahaya 100%. Penelitian dirancang menggunakan RAL. Data yang diperloleh diolah dengan uji T. Hasil penelitian menunjukkan bahwa pemberian naungan 45% menghasilkan petumbuhan dan produksi tanaman kacang hijau yang lebih rendah Mung bean (Vigna radiata) is one source of food that is rich in nutritional value. High population growth in Indonesia requires an adequate supply of food crops. Several species of legumes can be increased in growth and production by light intensity treatment. A decrease in light intensity to a certain level can affect plant growth. This study aims to analyze the effect of shade on the growth of green bean plants. The research was carried out in the Biology Laboratory of Plant Structure and Function. Green beans are planted in pots with a diameter of 30 cm, and a height of 40 cm. the treatment group was mung bean plants that were shaded with paranet with a light intensity of 45%, while the control group was a mung bean plant without shade, with a light intensity of 100%. The study was designed using RAL. The data obtained were processed by T test. The results showed that the provision of 45% shade resulted in lower growth and production of mung bean plants
Für Öffentliche Bibliotheken Maßstab für Qualität
Authors: Südkamp-Kriete Agnes 
Published: April 2022

Zusammenfassung
Seit 2009 können sich Öffentliche Bibliotheken in Niedersachsen als „Bibliothek mit Qualität und Siegel“ auszeichnen lassen. Das Zertifizierungsverfahren wurde im Auftrag des Niedersächsischen Ministeriums für Wissenschaft und Kultur und in enger Zusammenarbeit mit Bibliotheken des Landes für Bibliotheken unterschiedlicher Größe, Bibliothekstyp und Trägerschaft entwickelt. Ziel ist es, die interne Organisationstruktur in der Bibliothek zu optimieren und damit bessere qualitative Dienstleistungen für den Kunden zu erreichen. Die Teilnahme ist freiwillig und kostenlos, die Erfüllung der Anforderungen wird in einem Audit durch ausgebildete Fachkolleg*innen geprüft. 2019 wurde der Kriterienkatalog aufgrund der im Rahmen von Zertifizierungen gewonnenen Erkenntnisse grundlegend überarbeitet. Bislang haben 40 Bibliotheken den Zertifizierungsprozess erfolgreich durchlaufen. Alle Einrichtungen berichten über spürbare Erfolge durch die Teilnahme an „Bibliothek mit Qualität und Siegel“. Zu den vielen positiven Erfahrungen zählen neben dem Imagegewinn durch die Auszeichnung die gestiegene Wertschätzung seitens Politik und Verwaltung und die Motivationssteigerung im Mitarbeiterteam der Bibliothek.
Les limites épistémologiques des techniques numériques actuelles de l’intelligence artificielle en traduction
Authors: Flöter-Durr Margarete 
Published: April 2022

Abstract
The aim of this article is to analyze in detail the concepts underlying the digital techniques of artificial intelligence currently used in various fields, including translation. Based on this analysis, the epistemological limits of these techniques are examined, especially those resulting from the difficulty of modeling mechanisms of human rationality such as abduction or selection.In addition, the article explores the risks induced by the mass use of these techniques in translation, including their nature, extent and effects, and illustrates them with practical examples.
Some results on the total properk-connection number
Authors: Ma Yingbin , Zhang Hui 
Published: April 2022

AbstractIn this paper, we first investigate the total proper connection number of a graphGGaccording to some constraints ofG¯\overline{G}. Next, we investigate the total proper connection numbers of graphGGwith large clique numberω(G)=n−s\omega \left(G)=n-sfor1≤s≤31\le s\le 3. Finally, we determine the total properkk-connection numbers of circular ladders, Möbius ladders and all small cubic graphs of order 8 or less.
“Corrective Intervention” versus “Unfinished Revolution”: Transitions byReformaand the Military in Turkey and Greece
Authors: Tzortzis Ioannis 
Published: April 2022

AbstractThe article compares the failed self-transformation attempt in 1973 in Greece and the actual transition that occurred in 1983 in Turkey. These two cases of regime-initiated transitions to democracy with differing outcomes beg the question: If the 1973 transition in Greece led to a crippled democracy controlled by the military (as in Turkey 10 years later), why was it brought to an abrupt end by the very group that it was supposed to benefit—i.e. the military themselves? The author seeks to answer this question by comparing the position of the Turkish and Greek military in their respective power structures, which produced different regimes (hierarchical in Turkey vs. non-hierarchical in Greece). Moreover, in both cases, the transitions were not perceived as equally benefitting the military—hence the different outcomes, i.e. the failure of the Greek transition and the problematic democracy in Turkey.
Dinamika Kesejahteraan Psikologis Guru Honorer SD Negeri 02 Tiudan, Kecamatan Gondang, Kabupaten Tulungagung
Authors: Ghaybiyyah Faatihatul , Mahpur Mohammad 
Published: April 2022

Guru honorer merupakan guru yang diangkat secara resmi oleh pemerintah untuk mengatasi kekurangan guru (Mulyasa, 2006). Birokrasi pemerintah yang kurang memperhatikan hak guru honorer membuat guru honorer harus memutar otak agar bisa mencukupi kebutuhan hidup sehari-hari. Hal ini bukan hanya terjadi di satu wilayah saja, namun menyebar di seluruh wilayah di Indonesia. Pemerintah diharapkan bisa memberikan perhatian khusus bagi guru-guru yang ada di seluruh Indonesia, utamanya adalah guru honorer. Penelitian ini bertujuan untuk mengetahui dinamika kesejahteraan psikologis guru honorer SD Negeri 02 Tiudan, upaya guru honorer untuk menghadapi situasi sulit, upaya yang dilakukan guru honorer untuk mencapai kesejahteraan psikologis. Metode yang digunakan dalam penelitian ini adalah fenomenologi. Subjek dalam penelitian ini berjumlah dua orang. Subjek yang pertama dengan karakteristik perempuan berada pada usia 33 tahun yang telah menjadi guru selama 11 tahun di SD Negeri 02 Tiudan. Sedangkan subjek yang kedua dengan karakteristik laki-laki berada pada usia 33 tahun yang telah menjadi guru honorer selama 8 tahun di SD Negeri 02 Tiudan. Hasil penelitian menunjukkan bahwa dinamika kesejahteraan psikologis pada guru honorer SD Negeri 02 Tiudan ditunjukkan secara signifikan oleh kedua subjek. Terdapat dinamika kesejahteraan psikologis pada kedua subjek, yakni perubahan dalam fisik, psikologis, finansial, spiritual, sosial, dan kognitif. Kesimpulan dalam penelitian ini adalah terdapat dinamika kesejahteraan psikologis pada guru honorer SD Negeri 02 Tiudan. Dinamika ini mengacu pada adanya perubahan yang signifikan pada kedua subjek. Upaya kedua subjek untuk menghadapi keadaan sulit adalah dengan berusaha memaksimalkan potensi yang dimiliki kedua subjek. Sedangkan untuk upaya mencapai kesejahteraan psikologis, kedua subjek mempunyai usaha yang berbeda untuk mencapai kesejahteraan psikologis. Subjek pertama mempunyai usaha yang linier dalam keilmuannya yakni membuka bimbingan belajar, sedangkan subjek yang kedua adalah memilih untuk membuka bisnis makanan, minuman, dan pulsa.
Dampak Intervensi Komunitas Terhadap Kebersyukuran Orang Tua Anak Down Syndrome Di Yayasan Persatuan Orang Tua Anak Dengan Down Syndrome (Potads) Pejaten
Authors: Nazhifah Farah Salsabila , Arwan Artiarini Puspita 
Published: April 2022

Ketika orangtua mengetahui anaknya didiagnosis Down Syndrome, maka akan terjadi konflik dalam diri masing-masing baik sang ayah maupun sang ibu. Konflik tersebut terkait dengan keinginan dan harapan yang mungkin tidak dapat terpenuhi untuk memiliki anak normal yang bisa dibanggakan dalam lingkungan sosialnya,maka pada saat itulah muncul kekecewaan yang mendalam. Karena hal tersebut, peneliti tertarik untuk meneliti dampak intervensi komunitas yang diadakan oleh Yayasan POTADS terhadap kebersyukuran orang tua anak down syndrome. Penelitian ini menggunakan metode kualitatif dengan pendekatan deskriptif. Data penelitian ini dihasilkan dari pengumpulan data primer yaitu dari hasil wawancara, dan observasi dan dokumentasi, juga dari data sekunder yaitu hasil dari referensi dalam bentuk buku-buku yang relevan dengan tema penelitian untuk mendukung dan melengkapi data-data dilapangan. Subjek dalam penelitian ini terdiri dari 1 orang Wakil Ketua 2 Yayasan POTADS, 1 orang Psikolog, dan 3 orang tua anak down syndrome yang tergabung di POTADS, dan untuk pengambilan sample, peneliti menggunakan purposive sampling. Adapun hasil temuan yang peneliti dapatkan mengenai intervensi komunitas yang diberikan oleh Yayasan POTADS kepada orang tua anak down syndrome dapat dilihat dari adanya peningkatan rasa bersyukur dan penerimaan dirinya semenjak awal bergabung dengan POTADS, dan semakin bertambah ketika mengikuti berbagai kegiatan intervensi komunitas seperti melalui self help group, seminar, dan kopdar. Hal ini di tandai dengan memperlakukan dan mendidik anak down syndromenya menjadi lebih baik dan percaya diri.
Strategi Coping Stres Ibu Rumah Tangga dalam Menghadapi Kesulitan Ekonomi pada Masa Pandemi COVID-19 di Kota Bekasi
Authors: Maharani Nurtia , Arwan Artiarini Puspita 
Published: April 2022

Abstract: In 2020, the Covid-19 virus outbreak will affect a person's economy and health (physical or psychological). This situation makes some people feel stressed and have to survive in this situation. Everyone has a different way of dealing with the problems they face and religion has a role in helping to deal with problems for each of its adherents. This research uses a qualitative method with a case study approach. The research subjects consisted of 3 housewives. The data collection technique used a purpose sampling technique. Analysis of the data used is by means of data reduction, data presentation and drawing conclusions. The results showed that the coping strategies used were problem focus coping (planful problem solving and seeking social support) and emotional focused coping (positive reapraisal and self controlling). The description of the religiosity of the three informants in conditions of economic difficulty during the Covid-19 pandemic has a good level of religiosity, therefore the dimension of belief has a positive impact on worship and the behavior of the informants.Abstrak: Pada tahun 2020 merebaknya virus Covid-19 sehingga mempengaruhi ekonomi dan kesehatan (fisik atau psikologis) seseorang. Keadan tersebut membuat sebagian masyarakat merasa stres dan harus tetap bertahan dalam situasi ini. Setiap orang memiliki cara yang berbeda-beda terhadap masalah yang dihadapinya dan agama memiliki peran dalam membantu menghadapi permasalahan bagi setiap pemeluknya. Penelitian ini menggunakan metode kualitatif dengan pendekatan studi kasus. Subjek penelitian terdiri dari 3 ibu rumah tangga. Teknik pengambilan data menggunakan teknik purpose sampling. Analisis data yang digunakan yaitu dengan cara reduksi data, penyajian data dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa strategi coping yang digunakan yaitu problem focus coping (planful problem solving dan seeking social support) dan emotional focused coping (positive reapraisal dan self controlling). Gambaran religiusitas ketiga informan pada kondisi kesulitan ekonomi di masa pandemi Covid-19 memiliki tingkat religiusitas yang baik, oleh karena itu dimensi keyakinan memberikan dampak yang positif terhadap ibadah dan perilaku informan.
Peran Penyuluh Agama Islam dalam Membangun Moderasi Beragama Berbasis Literasi pada Era Media Baru 5.0 di Kabupaten Majalengka
Authors: Susanto Agus , Ulfah Maya 
Published: April 2022

Abstract: This study is aimed to determine several strategic alternatives by maximizing the role of counsellor of Islam in developing religious moderation based on literacy in the new media era of 5.0 in Majalengka Regency. In this study, the author used a mixed methodology, a methode that combine qualitative and quantitative approaches and used a SWOT analysis as a knife analysis to examine internal and external factors that influence the counsellor of Islam in developing religious moderation based on literacy in the new media era of 5.0 in Majalengka Regency. Based on the results of IFAS-EFAS, it is discovered that the role of counsellor of Islam in developing religious moderation based on literacy in the new media era of 5.0 in Majalengka Regency is relatively good and must be maintained because it has enormous potential for public benefit. The existing internal and external factors basically becomes a big support for the role of the counsellor of Islam.Abstrak: Tujuan penelitian ini adalah untuk menentukan berbagai alternatif strategis dengan memaksimalkan peran Penyuluh Agama Islam dalam membangun moderasi beragama berbasis literasi di Era Media Baru 5.0 di Kabupaten Majalengka. Penelitian ini menggunakan metode penelitian campuran (mixed methodology), metode yang memadukan pendekatan kualitatif dan kuantitatif dan menggunakan analisis SWOT sebagai pisau analisis untuk mengkaji faktor-faktor internal dan faktor-faktor eksternal yang mempengaruhi Penyuluh Agama Islam dalam membangun moderasi beragama berbasis literasi di Era Media Baru 5.0 di Kabupaten Majalengka. Berdasarkan hasil IFAS-EFAS, diketahui bahwa peran Penyuluh Agama Islam dalam membangun moderasi beragama berbasis literasi di Era Media Baru 5.0 di Kabupaten Majalengka sedah relatif baik dan harus dipertahankan karena memiliki potensi yang sangat besar untuk kemaslahatan publik. Keberadaan faktor-faktor internal dan eksternal, pada dasarnya, menjadi dukungan yang sangat besar bagi peran Penyuluh Agama Islam.