bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synergy Collaboration Management as A Catalyst for the Performance of Catholic Religious Education Teachers in Central Kalimatan
Authors: Hamu Fransiskus Janu , Pudjiarti Emiliana Sri 
Published: September 2022

This study aims to analyze the effect of transformational leadership on the performance of PAK (Christian Religious Education) teachers mediated by individual spiritual involvement, collaboration synergy and professional altruistic behavior as mediating variables. This type of research is survey research. The population in this study were PAK teachers in Central Kalimantan, while the sample in this study were 173 PAK teachers in Central Kalimantan. The instrument used to answer the research questions posed, the sampling technique was stratified random sampling. This study used primary data sources, questionnaires and the data analysis technique used is the Structural equation model with SmartPLS. The results of this study indicated that transformational leadership has a positive impact on PAK teacher performance by mediating PAK teacher spiritual involvement, collaborative synergy and professional altruistic behavior. Related to the involvement of spirituality, then a teacher will have meaning and value in life and work as a PAK teacher, where these meanings and values are highly dependent on the beliefs and values that underlie the motives in work which in turn encourages the birth of altruistic professional behavior that causes positive feelings.
AIDS em idosos: o cenário epidemiológico das regiões brasileiras entre 2010-2020
Authors: Lima Isabelle Catarine Reis , Nunes Beatriz Cunha Lisboa de Medeiros , Alencar Eva Luzia de Almeida , Bezerra Maria Beatriz Leandro , Souza Maria Jacqueline Nogueira de , Carvalho Maria Luisa Cabral , Soares Ana Larissa Fernandes de Holanda 
Published: September 2022

Objetivo: analisar a incidência epidemiológica da Síndrome da Imunodeficiência Adquirida (Sida/AIDS) em idosos, no período de 2010 a 2020, nas regiões do Brasil. Métodos: Trata-se de um estudo descritivo e quantitativo desenvolvido a partir do Departamento de Informática do Sistema Único de Saúde do Brasil (DATASUS). Analisou-se idosos com 60 anos de idade ou mais com tal patologia nesse intervalo de tempo, verificando as seguintes variáveis: ano de diagnóstico e notificação, sexo biológico, etnia, faixa etária, escolaridade e categoria de exposição. Resultados: Observou-se, no grupo em questão, 14.405 novos casos dessa doença no país, sendo predominante na região Sudeste com 5.565 casos. O perfil epidemiológico principal foi de homens, brancos, de 60-69 anos, com escolaridade de 1ª a 4ª série incompleta e com exposição nas relações heterossexuais. Vale mencionar, com relação ao nível escolar, que cerca de 60% dos idosos analisados se enquadram em categorias educacionais desde o analfabetismo à fundamental incompleto, reforçando a necessidade de um ensino em saúde para a população que transcenda a educação formal. Conclusão: Observou-se um elevado número de idosos com AIDS no período analisado, especialmente em heterossexuais e com escolaridade incompleta. Isso aponta a necessidade de políticas públicas em saúde direcionadas a esse grupo com abordagens sobre saúde sexual pelos profissionais da saúde.
Tecnologia educativa no cuidado domiciliar de crianças com atraso de desenvolvimento: um protocolo de revisão de escopo
Authors: Abreu Camila Cristine Tavares , Chaves Edna Maria Camelo , Silva Vanusa Maria Gomes Napoleão , Tavares Ana Raquel Bezerra Saraiva , Sousa Filho Manoel Pereira de 
Published: September 2022

Disponibilizar para criança chances para que tenha um desenvolvimento correto, talvez seja o de mais relevante para o ser humano. Nos primeiros anos de vida, um desenvolvimento satisfatório colabora para a formação de um ser humano com suas potencialidades desenvolvidas, com maior chance de tornar-se um sujeito mais seguro, preparado para enfrentar os obstáculos que a vida oferece, reduzindo assim as desigualdades sociais e econômicas da nossa sociedade. Trata-se de um protocolo de revisão de escopo sobre tecnologia educativa utilizada na promoção do cuidado domiciliar em crianças com atraso no desenvolvimento infantil. Objetivou-se mapear as evidências na literatura acerca da temática abordada. O protocolo define os objetivos, critérios de elegibilidade, fontes de evidência, métodos de gráficos, resultados e conclusões relacionadas às perguntas e objetivos da Revisão de Escopo. Foi elaborado baseado no Preferred Reporting Items for Systematic Reviews and Meta Extension Scoping Rewiew e manual Joana Brigs Institute Evidence Syntesis.
Do ensinar e do aprender Direito por meio de metodologia ativa
Authors: Soares Leonardo Ferreira , Oliveira Evaldo Hipólito de , Azevedo Ana Maria Leite Guimarães de , Béchade Maria José Soares 
Published: September 2022

O curso de direito apresenta expectativas que irá proporcionar poder, status social e ganhos financeiros. Ao se deparar com o ensino jurídico em diversas escolas o aluno adentra na educação bancária descrita por Paulo Freire, onde o professor, sujeito ativo, deposita na cabeça do aluno, sujeito passivo, o conteúdo cobrado pelas ementas. No afã da construção do conhecimento onde o aluno seja um sujeito ativo do processo bem como, do repassar o conhecimento adquirido, numa troca constante. As metodologias ativas no ensino jurídico propiciam que os alunos aprendam através das descobertas, do desenvolvimento de suas habilidades analíticas e da sua motivação. Neste artigo apresentamos três metodologias ativas: O aprendizado baseado em problemas (PBL), metodologia do ensino jurídico centradas nos discentes propiciando que estes aprendam através das descobertas, do desenvolvimento de suas habilidades analíticas e da sua motivação. O aprendizado baseado em projetos (ABP), combinando várias estratégias de ensino (aulas expositivas, vídeos, provas, dinâmicas, experimentação) baseadas nos resultados que o professor almeja do aluno. O método da sala de aula invertida propõe a interação e o debate entre estudantes concedendo-o um papel ativo na aprendizagem. Neste sentido, um dos principais pilares é que, ao discutir um tópico com um colega, ele pode aprender com o outro, promovendo através desse diálogo uma aprendizagem conceitual. Faz-se necessário a adoção de tais métodos nas aulas ministradas nas ciências jurídicas, para formação de profissionais críticos e reflexivos, para que isso ocorra é preciso que os professores e gestores entendam e estejam aberto ao seu uso.
Na “trilha das misturas”: uma proposta para o ensino de ciências nos anos iniciais do ensino fundamental
Authors: Barcelos Arina Timbohiba , Bianco Gilmene 
Published: September 2022

Este trabalho apresenta os resultados de uma prática pedagógica que foi aplicada em uma turma do 4º ano do ensino fundamental de uma escola pública do município de Conceição da Barra – ES. A proposta pedagógica foi realizada no decorrer da disciplina Produção de Artefatos Pedagógicos em Ciências, ofertada pelo curso de Pós-Graduação Ensino na Educação Básica, da Universidade Federal do Espírito Santo (UFES), e teve como objetivo a produção de um artefato pedagógico baseado em um jogo de trilha que foi utilizado como recurso didático para promover a participação, interesse e fixação dos temas misturas homogêneas e heterogêneas e métodos de separação de misturas. Além disso, buscou-se verificar aplicabilidade do jogo didático, inserindo o lúdico como ferramenta de melhoria do processo de ensino aprendizagem. A prática pedagógica foi realizada em 3 etapas. Na primeira etapa foi realizada uma aula teórico/prática abordando o tema proposto. A segunda etapa se caracterizou pela aplicação do jogo e a terceira etapa foi referente a aplicação do questionário para avaliação do jogo didático, baseado na percepção dos educandos. Assim, após análise dos questionários verificou-se que a atividade desenvolvida foi significativa. Durante toda a intervenção pedagógica os alunos se mostraram curiosos, questionadores e entusiasmados com as atividades que foram propostas. Sendo assim, é de extrema importância a elaboração de práticas pedagógicas diversificadas com o objetivo de contribuir para que os alunos sejam mais participativos, motivados e, além disso, que consigam alcançar de forma significativa o aprendizado.
CGF-HLC-I repaired the bone defect repair of the rabbits mandible through tight junction pathway
Authors: Mao Yalin , Hu Miaoling , Chen Li , Chen Xiao , Liu Maohua , Zhang Menglian , Nie Minhai , Liu Xuqian 
Published: September 2022

Background: The human-like collagen I (HLC-I) combined concentrated growth factors was used to construct CGF-HLC-I composite biomaterials to repair the critical bone defect disease model of rabbit mandible. This study aimed to research the repair mechanism of CGF-HLC-I/Bio-Oss in rabbit mandibular critical bone defect, to provide a new treatment direction for clinical bone defect repair.Methods: The optimal concentration of HLC-I (0.75%) was selected in this study. Nine New Zealand white rabbits were randomly divided into 3 groups, normal control group, Bio-Gide/Bio-Oss and CGF-0.75%HLC-I/Bio-Oss group (n = 3, each group). CGF-0.75%HLC-I/Bio-Oss and Bio-Gide/Bio-Oss were implanted into rabbit mandibles, then X-ray, Micro-CT, HE and Masson staining, immunohistochemical staining and biomechanical testing were performed with the bone continuity or maturity at 4, 8 and 12 weeks after surgery. The repair mechanism was studied by bioinformatics experiments.Results: As the material degraded, the rate of new bone formation in the CGF-0.75% HLC-I/Bio-Oss group was better than that the control group by micro-CT. The biomechanical test showed that the compressive strength and elastic modulus of the CGF-0.75%HLC-I/Bio-Oss group were higher than those of the control group. HE and Masson staining showed that the bone continuity or maturity of the CGF-0.75%HLC-I/Bio-Oss group was better than that of the control group. Immunohistochemical staining showed significantly higher bone morphogenetic protein 2 (BMP2) and Runt-related transcription factor 2 (RUNX2) in the CGF-0.75%HLC-I/Bio-Oss group than the control group at 8 and 12 W and the difference gradually decreased with time. There were 131 differentially expressed proteins (DEPs) in the Bio-Gide/Bio-Oss and CGF-0.75%HLC-I/Bio-Oss groups, containing 95 up-regulated proteins and 36 down-regulated proteins. KEGG database enrichment analysis showed actinin alpha 1 (ACTN1) and myosin heavy-Chain 9 (MYH9) are the main potential differential proteins related to osteogenesis, and they are enriched in the TJs pathway.Conclusion: CGF-0.75%HLC-I/Bio-Oss materials are good biomaterials for bone regeneration which have strong osteoinductive activity. CGF-0.75%HLC-I/Bio-Oss materials can promote new bone formation, providing new ideas for the application of bone tissue engineering scaffold materials in oral clinics.
Secular trends in the epidemiologic patterns of peripheral artery disease and risk factors in China from 1990 to 2019: Findings from the global burden of disease study 2019
Authors: Gong Wei , Shen Shuhan , Shi Xiaojing 
Published: September 2022

BackgroundAn understanding of the epidemiologic patterns of peripheral artery disease is essential in public health policy-making. We aimed to assess secular trends in the epidemiologic patterns and risk factors of peripheral artery disease from 1990 to 2019 in China.Materials and methodsWe extracted data on prevalence, incidence, death, and disability-adjusted life years (DALYs) due to peripheral artery disease from the Global Burden of Disease study 2019. In addition, risk factors for peripheral artery disease were reported.ResultsThe age-standardized prevalence of peripheral artery disease significantly increased from 1330.42 to 1423.78 per 100,000 population, with an average annual percentage change (AAPC) of 0.16 [95% confidence interval (CI), 0.07 to 0.24] from 1990 to 2019 in China. In addition, the age-standardized mortality rate significantly increased, with an AAPC of 0.62 (95% CI, 0.54 to 0.7), contrasting with the significantly declining trend in age-standardized DALYs (AAPC, −0.45; 95% CI, −0.52 to −0.39) between 1990 and 2019. The age-standardized prevalence was almost three times higher in females than males [2022.13 (95% CI: 1750 to 2309.13) vs. 744.96 (95% CI: 644.62 to 850.82) per 100,000 population] in 2019. The age-specific incidence significantly increased in individuals aged 40–44, 45–49, 50–54, 55–59, and 60–64 years groups but decreased in 70–74, 75–79, and 80–84 years groups. The age and period effects showed that the relative risks of incident peripheral artery disease increased with age and time. The cohort assessment showed that the incidence decreased in successive birth cohorts. Smoking was identified as the risk factor that contributed the most to age-standardized DALYs of peripheral artery disease in 2019.ConclusionThe burden of peripheral artery disease showed unexpected patterns that varied by age, sex, and year in China. More attention should be given to addressing the increasing incidence among middle-aged individuals and mortality among males.
Remnant cholesterol is associated with cardiovascular mortality
Authors: Zhang Kerui , Qi Xiangyun , Zhu Fuyu , Dong Quanbin , Gou Zhongshan , Wang Fang , Xiao Li , Li Menghuan , Chen Lianmin , Wang Yifeng , Zhang Haifeng , Sheng Yanhui , Kong Xiangqing 
Published: September 2022

BackgroundGenetic, observational, and clinical intervention studies indicate that circulating levels of remnant cholesterol (RC) are associated with cardiovascular diseases. However, the predictive value of RC for cardiovascular mortality in the general population remains unclear.MethodsOur study population comprised 19,650 adults in the United States from the National Health and Nutrition Examination Survey (NHANES) (1999–2014). RC was calculated from non-high-density lipoprotein cholesterol (non-HDL-C) minus low-density lipoprotein cholesterol (LDL-C) determined by the Sampson formula. Multivariate Cox regression, restricted cubic spline analysis, and subgroup analysis were applied to explore the relationship of RC with cardiovascular mortality.ResultsThe mean age of the study cohort was 46.4 ± 19.2 years, and 48.7% of participants were male. During a median follow-up of 93 months, 382 (1.9%) cardiovascular deaths occurred. In a fully adjusted Cox regression model, log RC was significantly associated with cardiovascular mortality [hazard ratio (HR) 2.82; 95% confidence interval (CI) 1.17–6.81]. The restricted cubic spline curve indicated that log RC had a linear association with cardiovascular mortality (p for non-linearity = 0.899). People with higher LDL-C (≥130 mg/dL), higher RC [≥25.7/23.7 mg/dL in males/females corresponding to the LDL-C clinical cutoff point (130 mg/dL)] and abnormal HDL-C (&lt;40/50 mg/dL in males/females) levels had a higher risk of cardiovascular mortality (HR 2.18; 95% CI 1.13–4.21 in males and HR 2.19; 95% CI 1.24–3.88 in females) than the reference group (lower LDL-C, lower RC and normal HDL-C levels).ConclusionsElevated RC levels were associated with cardiovascular mortality independent of traditional risk factors.
First-episode olfactory hallucination in a patient with anxiety disorder: A case report
Authors: Jiang Xingmei , Yuan Yiwen , Li Zhixiong , Ou Ying , Li Zhe 
Published: September 2022

BackgroundOlfactory hallucination refers to olfactory perception in the absence of chemical stimuli. Although it has been associated with many neurological and psychotic disorders, it has rarely been reported as the first and only symptom in patients with anxiety disorder, and its treatment remains inadequate.Case summaryA 66-year-old woman who had been experiencing gradually worsening olfactory hallucinations for almost 4 years was diagnosed with generalized anxiety disorder. Olfactory hallucination disappeared after treatment with anti-anxiety drugs.ConclusionOlfactory hallucination can be the first and only symptom in patients with anxiety disorder and may be effectively treated with anti-anxiety medication. In fact, it can precede the diagnosis of anxiety disorder by several years.
Determinants of neonatal near-miss among neonates delivered in public hospitals of Ilu Abba Bor Zone, Southwest Ethiopia: An unmatched case–control study during the COVID-19 pandemic
Authors: Debele Gebiso Roba , Siraj Sabit Zenu , Tsegaye Dereje , Temesgen Ermiyas 
Published: September 2022

BackgroundThe neonatal period is the time with the highest risk of neonatal and infant mortality. The COVID-19 pandemic diverted resources from routine maternal health services, which raises the possibility of neonatal near misses (NNMs). To implement prompt treatments that could improve the standard of infant care and lower neonatal mortality, it has been theorized that pinpointing the determinants of NNM during this outbreak is crucial. In light of this, the current study identified the determinants of NNM in neonates delivered in public hospitals of Ilu Abba Bor Zone, South West Ethiopia.MethodsAn institution-based unmatched case–control study was conducted among randomly selected 303 (101 cases and 202 controls) neonates admitted to Mettu Karl Comprehensive Specialized Hospital (MKCSH) and Darimu Primary Hospital (DPH) from 1 November to 28 December 2020. Data were collected using interviewer-administered structured questionnaire and checklist. The collected data were coded and entered into Epi-Data version 4.6 and then exported to SPSS version 20 for analysis. Adjusted odds ratios (AOR) along with a 95% confidence interval was used to assess the strength of the association, and a p-value &lt; 0.05 was considered to declare the statistical significance in the multivariable logistic regression analysis.ResultA total of 303 (101 cases and 202 controls) neonates admitted to MKCSH and DPH were included in the study making a 97.4% response rate. In the multivariable logistic regression analysis, no formal maternal education [AOR = 3.534, 95% CI: (1.194–10.455)], Breech presentation during birth [AOR = 3.088, 95% CI: (1.029–9.268)], &lt; 4 antenatal care (ANC) visits [AOR = 1.920, 95% CI: (1.065–3.461], cesarean section delivery [AOR = 4.347, 95% CI: (1.718–10.996)], antepartum hemorrhage (APH) [AOR = 3.37, 95% CI: (1.23–9.24)], and hypertensive disorders of pregnancy (HDP) [AOR = 4.05, 95% CI: (2.36–11.05)] were independent determinants of NNM.ConclusionThe study's result revealed that factors such as education level, birth presentation, ANC visit, mode of delivery, APH, and HDP continued to be important determinants of the NNM in Ethiopia during this pandemic. Therefore, much work is needed to improve neonatal health by providing adequate ANC services and other identified potential determinant factors that predispose the newborn to life-threatening (near-miss) conditions especially during this pandemic.
Evaluating industry attempts to influence public health: Applying an ethical framework in understanding commercial determinants of health
Authors: Ndebele Paul , Krisko Perrin , Bari Imran , Paichadze Nino , Hyder Adnan A. 
Published: September 2022

ObjectivesThis paper explores industry influence on public health using a specific case study and applies an established ethical framework based on eleven principles to explore Commercial Determinants of Health (CDoH). It demonstrates an application of these principles to evaluate the ethical integrity of industry strategies and practices and their impacts on public health.MethodsUsing eleven a priori, deductive, ethical principles as codes, this paper conducted an in-depth analysis of 19 e-mail chains and accompanying documents made publicly available through the Freedom of Information Act (FOIA) from U.S. Right to Know (USRTK) sent between Coca-Cola representatives, lobbyists, academics, and the International Life Sciences Institute (ILSI), founded by former Coca-Cola executives.ResultsThe three principles violated most frequently amongst the documents were consumer sovereignty (n = 22), evidence-informed actions (n = 21), and transparency (n = 20). Similarly, codes that featured most regularly across documents were transparency (13 out of 19 documents), consumer sovereignty (13 out of 19 documents), evidence-informed actions (9 out of 19 documents), and social justice and equity (9 out of 19 documents). All eleven principles were applied at least four times throughout the documents; however, responsiveness (z = 12), moral responsibility (z = 16), and holism (z = 30) were the least relevant to the data set.ConclusionsThis case study of Coca-Cola demonstrates the usefulness of this ethics framework in reviewing actions of corporate actors in the promotion of products that are harmful to human health. It shows that the industry at times has low ethical integrity in their various strategies and practices to promote their products despite the negative impacts of these products on public health.
Effectiveness of minimally invasive surgery using incomplete phalangeal osteotomy for symptomatic curly toe of adults with a trapezoidal phalanx: An observational study
Authors: Ramírez-Andrés Leonor , Nieto-García Eduardo , Nieto-González Elena , López-Ejeda Noemí , Ferrer-Torregrosa Javier 
Published: September 2022

Background and aimsDigital deformity in flexion, varismus (external rotation), and adduction with the toe in both supraduction and infraduction are called clinocampodactyly or curly toe. All adult patients with symptoms and a diagnosis of semirigid/rigid curly toes underwent radiological examination to verify the presence of a trapezoidal phalanx. The purpose of this study was to quantitatively determine the degrees of improvement of a dysmetric phalanx after incomplete phalangeal osteotomy using minimally invasive surgery. The points of improvement were determined using the American Orthopedic Foot and Ankle Society (AOFAS) scale score.MethodsBetween May 2021 and June 2022, 30 patients diagnosed with curly toes underwent unicortical osteotomy of the affected phalanx. The convergence angle was measured and the AOFAS scale scores were compared.ResultsA total of 33 toes underwent surgery. The average reduction of the convergence angle was 9°. The average improvement in the AOFAS scale score was 53 points at 6 months and reached almost 90 points (89.9 ± 6.1 points).ConclusionsIncomplete phalangeal osteotomy performed with minimally invasive surgery of the trapezoidal phalanges of curly toes of adults can improve alignment and AOFAS scale scores.
Femoral head metastases from primary mucinous lung adenocarcinoma with left hip pain: A case report and literature review
Authors: Xue Hang , Zhou Wu , Zhang Zhenhe , Panayi Adriana C. , Xiong Yuan , Yang Shuhua , Mi Bobin , Liu Guohui , Liu Xianzhe 
Published: September 2022

BackgroundPrimary mucinous lung adenocarcinoma, a subtype of lung adenocarcinoma, is extremely rare. Currently, as there are no specific diagnostic features, it is easy to delay the diagnosis or even to misdiagnose when atypical symptoms are present.Case summaryThis case details a patient with primary mucinous lung adenocarcinoma and metastasis to the femoral head. The sole symptom was left hip pain and the initial diagnosis was isolated femoral head necrosis.ConclusionsBy presenting this rare case report and the experiences learned from it, we hope to assist clinicians to identify bone metastasis cases with non-typical symptoms in order to make the correct diagnosis as soon as possible.