bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between oral health and advisability of oral feeding in advanced cancer patients receiving palliative care: a cross-sectional study
Authors: Furuya Junichi , Suzuki Hiroyuki , Hidaka Rena , Matsubara Chiaki , Motomatsu Yuko , Kabasawa Yuji , Tohara Haruka , Sato Yuji , Miyake Satoshi , Minakuchi Shunsuke 
Published: March 2022

Abstract
Purpose
Maintenance of oral feeding is important in terms of maintaining and improving the quality of life in terminal cancer patients receiving palliative care. Although adequate oral health status is essential for oral feeding in hospitalized patients, the relationship between oral health and oral feeding in patients receiving palliative care remains unclear. This cross-sectional study aimed to examine how the general condition and oral health status of these patients relate to decisions regarding their nutritional intake methods.

Methods
This retrospective cross-sectional study included 103 terminal cancer patients (59 men and 44 women; mean age, 73.8 ± 10.9 years) who received palliative care between April 2017 and August 2019. The nutritional method was assessed using the Functional Oral Intake Scale (FOIS). We assessed two types of nutritional methods: (1) the method advised by the attending physician until the initial dental examination (FOIS-I) and (2) the recommended method based on consultation with a palliative care doctor and dentist after the initial oral examination (FOIS-R). Furthermore, the participants’ basic information and Dysphagia Severity Scale (DSS) and Oral Health Assessment Tool (OHAT) scores were assessed.

Results
There was a divergence between FOIS-I and FOIS-R. FOIS-R was significantly higher than FOIS-I (p < 0.001). Multiple regression analysis revealed that the time until death, DSS score, and OHAT score had a significant impact on determining the food form for oral feeding.

Conclusions
Appropriate oral health assessment is important in determining the food form and indication for oral feeding among patients receiving palliative care.
Corrosion, mechanical and bioactivity properties of HA-CNT nanocomposite coating on anodized Ti6Al4V alloy
Authors: Dalili Faezeh , Aghdam Rouhollah Mehdinavaz , Soltani Reza , Saremi Mohsen 
Published: March 2022

AbstractHydroxyapatite-carbon nanotubes (HA-CNTs) nanocomposite coating was applied by electrophoretic method on anodized Ti alloy to investigate its stability in simulated body fluid (SBF). The biocoating was characterized by using scanning electron microscope (SEM) for microstructure, X-ray diffraction (XRD) for crystallography. The effect of CNTs concentration on the coating properties was also investigated and found out that CNTs up to 5% has various improving effect on the system. It increased corrosion resistance and adhesion of the coating to the substrate and decreased the number of cracks on the coating. The results of the in vitro test showed that the cell viability increased with increasing the concentration of CNTs to 3 wt.% CNTs.
Assessment of groundwater quality for drinking and irrigation in the Timahdite–Almis Guigou area (Middle Atlas, Morocco)
Authors: Amrani Samir , Hinaje Said , El Fartati Mohamed , Gharmane Youssef , Yaagoub Driss 
Published: March 2022

AbstractThe groundwater in the Timahdite–Almis Guigou area flows through fluvio-lacustrine and volcanic formations of Plio-Quaternary age and Liassic limestone. The groundwater resources in this area are used for drinking water and irrigation of agricultural plots. 18 groundwater samples were collected for this study. The physico-chemical and bacteriological parameters analysed, such as temperature, electrical conductivity, pH, dissolved oxygen, Na+, K+, Ca2+, Mg2+, Cl−, HCO3−, SO42−, NO2−, NO3−, faecal Coliforms, total Coliforms and faecal Streptococci, are used to characterise the quality of the groundwater and its suitability for drinking and for irrigation. The Piper and Gibbs diagrams and the saturation index were used to study the hydrogeochemical characteristics of groundwater. The quality of these was assessed on the basis of bacteriological quantification and water quality index (WQI) for drinking, and calculation of sodium percentage (Na%), sodium adsorption ratio (SAR) and permeability index (PI) for irrigation. The mineral saturation index in groundwater indicates that only carbonate minerals tend to precipitate, especially in the form of dolomite. On the other hand, the evaporative minerals are still undersaturated. The bacteriological quality and the water quality index (WQI) of this area are considered to be generally good to poor quality, with the exception of a few points, near the public dump of Almis Guigou, plateau of Lamrijate (Timahdite), Aït Hamza and Aït Ghanem, that show significant bacterial contamination and high concentrations of sodium, chlorides and nitrates. According to the calculation of the (Na%), the (SAR) and (PI), the groundwater samples are suitable for irrigation.
Mathematical model of the combustion process for turbojet engine based on fuel properties
Authors: Białecki Tomasz 
Published: March 2022

AbstractThis paper presents the impact of the alternative fuels properties on the parameters characterizing the combustion process in a turbojet engine, expressed in the form of a mathematical model. Laboratory tests, bench tests and a regression analysis of the obtained results were conducted. The developed and published combustion process models were briefly described. It has been demonstrated that these models were insufficient in taking into account the impact of fuel properties on the course of the combustion process. The experimental data enabled developing a mathematical model of the combustion process using statistical methods. The developed model, unlike other currently known models, takes into account the chemical composition of the fuel to a greater extent, which is characterized by its physicochemical properties. Mathematical model enables predicting engine operating parameters and the emissions characteristics, based on analysing laboratory test results, and can be used as a tool verifying the environmental impact of new fuels, through predicting the exhaust gas emissions.
Effects of Climate Change on the Production of Polysaccharides and Phycobiliproteins by Nostoc commune Vaucher ex Bornet et Flahault
Authors: Llopis Paula , García-Abad Laura , Pretel María Teresa , Montero María Adriana , Jordán Manuel Miguel , Asencio Antonia Dolores 
Published: March 2022

AbstractNostoc commune synthesizes polysaccharides and phycobiliproteins under natural conditions, but little is known about how environmental changes could affect their production. In this study, colonies of N. commune were subjected to increases in ultraviolet radiation, ammonium concentration, electrical conductivity, and temperature, to assess the potential changes in the concentrations of polysaccharides and phycobiliproteins. The results indicate that UVB radiation significantly increased the synthesis of polysaccharides (F = 62.691; p < 0.01), while UVA radiation caused a significant increase in the production of total phycobiliproteins (F = 22.472, p < 0.01) phycocyanin (F = 8.546, p < 0.01), phycoerythrin (F = 12.876, p < 0.01), and allophycocyanin (F = 58.143, p < 0.001). Also, 50 µM NH4Cl significantly increased the synthesis of polysaccharides (F = 45.706; p < 0.01) while increased near significant total phycobiliproteins (F = 5.043, p < 0.1), phycoerythrins (F = 4.57, p < 0.1), allophycocyanin (F = 4.892, p < 0.1), and phycocyanin (F = 4.921, p < 0.1). Furthermore, a conductivity value of 4 mScm−1 enhanced near significant the production of polysaccharides (F = 4.816; p < 0.1) and phycocyanin (F = 9.728, p < 0.1). Nevertheless, a significant effect of total phycobiliproteins was observed (F = 23.686, p < 0.01), as well as allophycocyanin (F = 57.092, p < 0.001), and phycoerythrin (F = 13.928, p < 0.01). Finally, the optimal temperature for the synthesis of polysaccharides was 30 °C. Also, 30 ºC significantly increased the synthesis of total phycobiliproteins (F = 292.211, p < 0.001), as well as on phycocyanin (F = 126.433, p < 0.001) and allophycocyanin (F = 7.991, p < 0.05). These data indicate the ability of N. commune to modify its synthesis of polysaccharides and phycobiliproteins in response to extreme environmental conditions related to climate change, underscoring the interest in N. commune for future applied research on the biotechnological and pharmaceutical production of both types of compounds.
Foliated Schwarz symmetry of solutions to a cooperative system of equations involving nonlocal operators
Authors: Greco Antonio , Jarohs Sven 
Published: March 2022

AbstractIn this paper, we prove foliated Schwarz symmetry of solutions to a cooperatively coupled system of equations involving nonlocal operators. Here, the class of nonlocal operators covers in particular the case of the fractional Laplacian. Moreover, we give an explicit example of a nonlocal nonlinear system, in which our result can be applied.
Introduction to the Special Issue on the International Joint Conference on Rules and Reasoning, RuleML+RR 2019
Authors: FODOR PAUL , MONTALI MARCO 
Published: March 2022

AbstractThis special issue of Theory and Practice of Logic Programming consists of extended versions of five selected papers from the 3rd International Joint Conference on Rules and Reasoning (RuleML+RR 2019). RuleML+RR 2019 was held in conjunction with the 5th Global Conference on Artificial Intelligence, GCAI 2019, as part of the Bolzano Rules and Artificial INtelligence Summit in Bolzano, Italy, from 17 to 19 of September 2019.
Extreme Hydrometeorological Events, a Challenge for Gravimetric and Seismology Networks
Authors: Van Camp Michel , de Viron Olivier , Dassargues Alain , Delobbe Laurent , Chanard Kristel , Gobron Kevin 
Published: March 2022

AbstractExtreme events will become more common due to global change, requiring enhanced monitoring and pushing conventional observation networks to their limits. This encourages us to combine all the possible sources of information to obtain a complete picture of extreme events and their evolution. This commentary builds on an example of the July 2021 catastrophic floods that hit northwest Europe, for which the use of seismometer and gravimeter captures complementary data and brings a new understanding of the event and its dynamics. A sudden increase in seismic noise coincides with the testimony reporting on a “tsunami” downstream of the geophysical station. Concurrently, the gravimeter showed increasing saturation of the weathered zone, showing less and less water accumulation and increasing runoff. When rain re‐intensified after a 3‐hr break, the subsoil's saturation state induced an accelerated runoff increase, as revealed by the river flow, in a much stronger way than during the rainy episodes just before. We show that the gravimeter detected the saturation of the catchment subsoil and soil in real‐time. When the rain re‐intensified, this saturation resulted in a sudden, devastating and deadly flood. Our study opens up the possibility of integrating real‐time gravity in early warning systems for such events.
Driving chemical reactions with polariton condensates
Authors: Pannir-Sivajothi Sindhana , Campos-Gonzalez-Angulo Jorge A. , Martínez-Martínez Luis A. , Sinha Shubham , Yuen-Zhou Joel 
Published: March 2022

AbstractWhen molecular transitions strongly couple to photon modes, they form hybrid light-matter modes called polaritons. Collective vibrational strong coupling is a promising avenue for control of chemistry, but this can be deterred by the large number of quasi-degenerate dark modes. The macroscopic occupation of a single polariton mode by excitations, as observed in Bose-Einstein condensation, offers promise for overcoming this issue. Here we theoretically investigate the effect of vibrational polariton condensation on the kinetics of electron transfer processes. Compared with excitation with infrared laser sources, the vibrational polariton condensate changes the reaction yield significantly at room temperature due to additional channels with reduced activation barriers resulting from the large accumulation of energy in the lower polariton, and the many modes available for energy redistribution during the reaction. Our results offer tantalizing opportunities to use condensates for driving chemical reactions, kinetically bypassing usual constraints of fast intramolecular vibrational redistribution in condensed phase.
Hollow-core optical fibre sensors for operando Raman spectroscopy investigation of Li-ion battery liquid electrolytes
Authors: Miele Ermanno , Dose Wesley M. , Manyakin Ilya , Frosz Michael H. , Ruff Zachary , De Volder Michael F. L. , Grey Clare P. , Baumberg Jeremy J. , Euser Tijmen G. 
Published: March 2022

AbstractImproved analytical tools are urgently required to identify degradation and failure mechanisms in Li-ion batteries. However, understanding and ultimately avoiding these detrimental mechanisms requires continuous tracking of complex electrochemical processes in different battery components. Here, we report an operando spectroscopy method that enables monitoring the chemistry of a carbonate-based liquid electrolyte during electrochemical cycling in Li-ion batteries with a graphite anode and a LiNi0.8Mn0.1Co0.1O2 cathode. By embedding a hollow-core optical fibre probe inside a lab-scale pouch cell, we demonstrate the effective evolution of the liquid electrolyte species by background-free Raman spectroscopy. The analysis of the spectroscopy measurements reveals changes in the ratio of carbonate solvents and electrolyte additives as a function of the cell voltage and show the potential to track the lithium-ion solvation dynamics. The proposed operando methodology contributes to understanding better the current Li-ion battery limitations and paves the way for studies of the degradation mechanisms in different electrochemical energy storage systems.
Distinct genomic landscape of Chinese pediatric acute myeloid leukemia impacts clinical risk classification
Authors: Liu Ting , Rao Jianan , Hu Wenting , Cui Bowen , Cai Jiaoyang , Liu Yuhan , Sun Huiying , Chen Xiaoxiao , Tang Yanjing , Chen Jing , Wang Xiang , Wang Han , Qian Wubin , Mao Binchen , Guo Sheng , Wang Ronghua , Liu Yu , Shen Shuhong 
Published: March 2022

AbstractStudies have revealed key genomic aberrations in pediatric acute myeloid leukemia (AML) based on Western populations. It is unknown to what extent the current genomic findings represent populations with different ethnic backgrounds. Here we present the genomic landscape of driver alterations of Chinese pediatric AML and discover previously undescribed genomic aberrations, including the XPO1-TNRC18 fusion. Comprehensively comparing between the Chinese and Western AML cohorts reveal a substantially distinct genomic alteration profile. For example, Chinese AML patients more commonly exhibit mutations in KIT and CSF3R, and less frequently mutated of genes in the RAS signaling pathway. These differences in mutation frequencies lead to the detection of previously uncharacterized co-occurring mutation pairs. Importantly, the distinct driver profile is clinical relevant. We propose a refined prognosis risk classification model which better reflected the adverse event risk for Chinese AML patients. These results emphasize the importance of genetic background in precision medicine.
‘Citizens’ Attitudes Under Covid19’, a cross-country panel survey of public opinion in 11 advanced democracies
Authors: Brouard Sylvain , Foucault Martial , Michel Elie , Becher Michael , Vasilopoulos Pavlos , Bono Pierre-Henri , Sormani Nicolas 
Published: March 2022

AbstractThis article introduces data collected in the Citizens’ Attitudes Under Covid-19 Project (CAUCP), which surveyed public opinion throughout the Covid-19 pandemic in 11 democracies between March and December 2020. In this paper, we present a unique cross-country panel survey of citizens’ attitudes and behaviors during a worldwide unprecedented health, governance, and economic crisis. This dataset investigates the behavioral and attitudinal consequences of multifaceted Covid19 crisis across time and contexts. In this paper, we describe the design of the CAUCP and the descriptive features of the dataset; we also present promising research prospects.
The first 3D analysis of the sphenoid morphogenesis during the human embryonic period
Authors: Utsunomiya Natsuko , Katsube Motoki , Yamaguchi Yutaka , Yoneyama Akio , Morimoto Naoki , Yamada Shigehito 
Published: March 2022

AbstractThe sphenoid has a complicated shape, and its morphogenesis during early development remains unknown. We aimed to elucidate the detailed morphogenesis of the sphenoid and to visualize it three-dimensionally using histological section (HS) and phase-contrast X-ray CT (PCX-CT). We examined 65 specimens using HS and 57 specimens using PCX-CT, and summarized the initial morphogenesis of the sphenoid during Carnegie stage (CS) 17 to 23. The 3D models reconstructed using PCX-CT demonstrated that some neural foramina have the common process of "neuro-advanced" formation and revealed that shape change in the anterior sphenoid lasts longer than that of the posterior sphenoid, implying that the anterior sphenoid may have plasticity to produce morphological variations in the human face. Moreover, we measured the cranial base angle (CBA) in an accurate midsagittal section acquired using PCX-CT and found that the CBA against CS was largest at CS21. Meanwhile, CBA against body length showed no striking peak, suggesting that the angulation during the embryonic period may be related to any developmental events along the progress of stages rather than to a simple body enlargement. Our study elucidated the normal growth of the embryonic sphenoid, which has implications for the development and evolution of the human cranium.
Using machine learning to uncover the relation between age and life satisfaction
Authors: Kaiser Micha , Otterbach Steffen , Sousa-Poza Alfonso 
Published: March 2022

AbstractThis study applies a machine learning (ML) approach to around 400,000 observations from the German Socio-Economic Panel to assess the relation between life satisfaction and age. We show that with our ML-based approach it is possible to isolate the effect of age on life satisfaction across the lifecycle without explicitly parameterizing the complex relationship between age and other covariates—this complex relation is taken into account by a feedforward neural network. Our results show a clear U-shape relation between age and life satisfaction across the lifespan, with a minimum at around 50 years of age.
Speed-accuracy tradeoffs influence the main sequence of saccadic eye movements
Authors: Guadron Leslie , van Opstal A. John , Goossens Jeroen 
Published: March 2022

AbstractSeveral studies have proposed that an optimal speed-accuracy tradeoff underlies the stereotyped relationship between amplitude, duration and peak velocity of saccades (main sequence). To test this theory, we asked 8 participants to make saccades to Gaussian-blurred spots and manipulated the task’s accuracy constraints by varying target size (1, 3, and 5°). The largest targets indeed yielded more endpoint scatter (and lower gains) than the smallest targets, although this effect subsided with target eccentricity. The main sequence depended on several interacting factors: saccade latency, saccade gain and target size. Early saccades, which were faster than amplitude-matched late saccades, followed the target-size dependency one would expect from a speed-accuracy tradeoff process. They had higher peak velocities and shorter durations for larger targets than for smaller targets. For late saccades, however, the opposite was found. Deviations from the main sequence also covaried with saccade gain, in line with the idea that motor noise underlies part of the endpoint variability. Thus, our data provide partial evidence that the saccadic system weighs the detrimental effects of motor noise on saccade accuracy against movement duration and speed, but other factors also modulate the kinematics. We discuss the possible involvement of parallel saccade pathways to account for our findings.
Structural and mechanistic basis for redox sensing by the cyanobacterial transcription regulator RexT
Authors: Li Bin , Jo Minshik , Liu Jianxin , Tian Jiayi , Canfield Robert , Bridwell-Rabb Jennifer 
Published: March 2022

AbstractOrganisms have a myriad of strategies for sensing, responding to, and combating reactive oxygen species, which are unavoidable consequences of aerobic life. In the heterocystous cyanobacterium Nostoc sp. PCC 7120, one such strategy is the use of an ArsR-SmtB transcriptional regulator RexT that senses H2O2 and upregulates expression of thioredoxin to maintain cellular redox homeostasis. Different from many other members of the ArsR-SmtB family which bind metal ions, RexT has been proposed to use disulfide bond formation as a trigger to bind and release DNA. Here, we present high-resolution crystal structures of RexT in the reduced and H2O2-treated states. These structures reveal that RexT showcases the ArsR-SmtB winged-helix-turn-helix fold and forms a vicinal disulfide bond to orchestrate a response to H2O2. The importance of the disulfide-forming Cys residues was corroborated using site-directed mutagenesis, mass spectrometry, and H2O2-consumption assays. Furthermore, an entrance channel for H2O2 was identified and key residues implicated in H2O2 activation were pinpointed. Finally, bioinformatics analysis of the ArsR-SmtB family indicates that the vicinal disulfide “redox switch” is a unique feature of cyanobacteria in the Nostocales order, presenting an interesting case where an ArsR-SmtB protein scaffold has been evolved to showcase peroxidatic activity and facilitate redox-based regulation.
Highly efficient and selective electrocatalytic hydrogen peroxide production on Co-O-C active centers on graphene oxide
Authors: Zhang Bin-Wei , Zheng Tao , Wang Yun-Xiao , Du Yi , Chu Sheng-Qi , Xia Zhenhai , Amal Rose , Dou Shi-Xue , Dai Liming 
Published: March 2022

AbstractElectrochemical oxygen reduction provides an eco-friendly synthetic route to hydrogen peroxide (H2O2), a widely used green chemical. However, the kinetically sluggish and low-selectivity oxygen reduction reaction (ORR) is a key challenge to electrochemical production of H2O2 for practical applications. Herein, we demonstrate that single cobalt atoms anchored on oxygen functionalized graphene oxide form Co-O-C@GO active centres (abbreviated as Co1@GO for simplicity) that act as an efficient and durable electrocatalyst for H2O2 production. This Co1@GO electrocatalyst shows excellent electrochemical performance in O2-saturated 0.1 M KOH, exhibiting high reactivity with an onset potential of 0.91 V and H2O2 production of 1.0 mg cm−2 h−1 while affording high selectivity of 81.4% for H2O2. Our combined experimental observations and theoretical calculations indicate that the high reactivity and selectivity of Co1@GO for H2O2 electrogeneration arises from a synergistic effect between the O-bonded single Co atoms and adjacent oxygen functional groups (C-O bonds) of the GO present in the Co-O-C active centres.