bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of electroclinical features of nonconvulsive status epilepticus: a study of four cases
Authors: Wu Dan , Liu Xiaoyun , Yao Xingqi , Yang Yanfeng , Zhang Jun , Yang Haoran , Sun Wei 
Published: April 2022

AbstractBackgroundThe nonconvulsive status epilepticus (NCSE) is an epileptic condition characterized by little or no obvious symptoms, thus is often easily to be underrecognized, underdiagnosed or even undetected by clinicians. This article is written to advance the recognition and diagnosis of NCSE.Case presentationFour cases of NCSE were reported and their semiology, electroencephalogram (EEG) features, etiology, treatment and prognosis were retrospectively analyzed. Most of the 4 cases presented with impaired consciousness (confused, slow reaction and lags in response) and some strange behaviors (being upset and restless or washing hands repeatedly). None of them had any obvious motor symptoms like tonic or clonic movements. EEG of the 4 cases initially manifested with either a focal or a generalized onset, then evolved into spike-and-wave pattern gradually. With a favorable response to antiepileptic drugs, they all had a good outcome without any sequela.ConclusionsNCSE is much more common than was considered in the past, which is featured by little or no evidence of movement or other symptoms. NCSE can lead to a favorable outcome in most patients.
Rat bite fever in a total knee arthroplasty: an unusual case of periprosthetic joint infection
Authors: Fokkema Anne Theunis , Kampschreur Linda Martine , Pirii Loredana Elena , Zijlstra Wierd Pieter 
Published: April 2022

Abstract
Background
Periprosthetic joint infection (PJI) is a serious complication of orthopedic arthroplasty surgery. Rat bite fever is a rare infection with Streptobacillus moniliformis (S. moniliformis). Rat bite fever can lead to serious complications such as pyogenic infection of joints, bacteremia, endocarditis and even death. We hereby present the first case of a patient with a total knee arthroplasty, infected with S. moniliformis, successfully treated by surgical debridement, antibiotics and implant retention (DAIR).

Case presentation
The patient was a 64-year-old female. S. moniliformis was isolated from blood cultures and an aspirate of the left knee by 16S rRNA gene polymerase chain reaction technique. It was assumed that the S. moniliformis had a systemic origin and secondarily infected the knee due to fever nine days before the onset of symptoms of the knee. The patient was successfully managed with DAIR and intravenous administration of ceftriaxone for six weeks and oral doxycycline for another six weeks.

Conclusions
S. moniliformis is a rare pathogen and is difficult to culture. The 16S rRNA sequencing is helpful in the determination of a causative microorganism in the case of a culture-negative PJI. A DAIR procedure in combination with 12 weeks of antibiotics could successfully treat S. moniliformis prosthetic joint infection.
Three uncommon mutations of the SLC12A3 gene in gitelman syndrome: case reports and review of the literature
Authors: Akpinar Gozetici Melis , Ersoy Dursun Fadime , Dursun Hasan 
Published: April 2022

Abstract
Background
Gitelman syndrome is a rare autosomal recessive salt-wasting tubulopathy characterized by low potassium and magnesium levels in the blood, decreased excretion of calcium in the urine, and metabolic alkalosis. It is commonly caused by an inactivating mutation in the SLC12A3 gene (16q13), which encodes a thiazide-sensitive sodium chloride cotransporter. Here, we present three cases with the same clinical and laboratory findings that showed different mutations in the SLC12A3 gene.

Case presentation
Three children, a 14-year-old boy, a 7-year-old girl, and an 11-year-old boy, were admitted to our hospital at different times with nausea, weakness, muscle cramps in hands, and failure to thrive complaints. Blood tests showed hypokalemia, hypomagnesemia and metabolic alkalosis. Patients were referred to Pediatric Nephrology Clinic and diagnosed with Gitelman syndrome. Genetic tests of three cases showed homozygous mutations of c.1928C > T, p.Pro643Leu, c.248G > A, p.Arg83Gln, and c.1919A > G, p.N640S in the SLC12A3 gene exists, respectively. Potassium chloride, magnesium replacements, and indomethacin were given for treatment to patients. During follow-up, patients' heights and weights were increased dramatically, and nausea complaints were over.

Conclusion
Different mutations in the SLC12A3 gene in Gitelman syndrome can be detected but clinical, and laboratory findings were generally similar. Treatment with potassium, magnesium supplements, and indomethacin showed significant improvements in symptoms.
Greater trochanteric pain syndrome: a simplified MRI approach
Authors: Amin Wessam Mohammad , Abdelkerim Amr Ai 
Published: April 2022

Abstract
Background
Greater trochanteric pain syndrome (GTPS) refers to pain and tenderness over the greater trochanter. It is a common entity of lateral hip pain that is usually related to the overuse or small injuries of the gluteus medius or minimus tendons and their surrounding bursae. MRI is the favored modality for evaluation of the hip region disorders. Treatment options ranges from conservative to surgical treatment.

Results
Trochanteric (sub-gluteal maximus) bursal fluid was the most common finding found in 55 hips (73%), followed by gluteal tendinosis (64%) and partial thickness gluteal tendon tear (29%). Full thickness tear of the gluteal tendons occurred in 10 hips (13%). The relation between gluteal tendinosis and greater trochanteric bursal fluid was statistically significant (P < 0.05) with sensitivity and specificity of 85% and 78% respectively.

Conclusion
MRI should be utilized in a simple systemized approach by MSK radiologist in order not to miss a finding that may influence the surgical outcome of the patient presenting with GTPS.
Tips for avoiding common mistakes in out-of-hospital diagnosis of carbon monoxide poisoning
Authors: Fucili G. , Brauzzi M. 
Published: April 2022

AbstractAcute carbon monoxide poisoning is the leading cause of intoxication from exogenous substances in the world. It is also a major cause of morbidity and mortality due to poisoning in the USA. In the USA, it determines to 50,000 visits per year in emergency departments with a mortality ranging from 1 to 3%. Although prevalence and incidence data reveal the large impact of carbon monoxide poisoning on public health, some studies have shown that errors in its diagnosis have a high incidence (30%) and that awareness campaigns have allowed the reduction of the same to 5%. In addition, many diagnostic and/or therapeutic errors were found both in small first aid situations and in the context of rescue units belonging to prestigious hospitals. To formulate a diagnosis, the collection of clues from the environment in which the patient is found is essential. Especially when the routine use of environmental gas detectors or handheld CO-oximeters is not possible, the emergency doctor, in addition to concentrating on the clinical presentation of the case, will have to give a quick overview of the patient and his environment. In addition to age, sex, and already known comorbidities, it is not irrelevant to evaluate socio-economic and cultural characteristics, hygiene conditions, habits, etc.The purpose of this study is to provide useful information to the doctor who comes first to the site of intoxication to reduce diagnostic and therapeutic errors in the pre- and intra-hospital phase as much as possible.
Migraine in children population - systemic review
Authors: Wieteska Małgorzata , Maj Dominik , Gendek Karolina , Bąk Weronika , Chrościńska-Krawczyk Magdalena 
Published: April 2022

Introduction and objective: Migraine constitutes the main reason for acute and recurrent headache among children globally. It is a primary headache syndrome that affects from 3 up to 10% of paediatric population. The frequency of migraine increases with age up to puberty. The aim of this study is to systemize recent knowledge about migraine in children. The information used in the presented analysis was obtained by searching academic research databases: Google Scholar and PubMed.
An abbreviated description of the state of knowledge: The exact pathogenesis of migraine remains unknown, but involvement of nervous system, cardiovascular system, genetic predisposition and environmental factors are considered in the development of disease. Symptoms of migraine vary between individuals and can be wide-ranging. They may resemble disorders such as tension headache, cluster headache, epilepsy, brain tumour or ischemic stroke. The diagnostic process is based on anamnesis, and may therefore be challenging in children because of difficulties related to communication. Symptom-relieving therapy of migraine is well-established in contrast to pharmacological prophylactic treatment which is not sufficiently evidence-based.
Summary: Migraine remains a global problem in the paediatric population. The condition is associated not only with physical pain, but also it leads to many long-term complications such as emotional problems and social disruption. Lack of safe and effective preventive medical therapies is a driving factor to improve trials of migraine treatment in the future.
Social Inequality and the Spread of Misinformation
Authors: Mostagir Mohamed , Siderius James 
Published: April 2022

We study the spread of misinformation in a social network characterized by unequal access to learning resources. Agents use social learning to uncover an unknown state of the world, and a principal strategically injects misinformation into the network to distort this learning process. A subset of agents throughout the network is endowed with knowledge of the true state. This gives rise to a natural definition of inequality: privileged communities have unrestricted access to these agents, whereas marginalized communities do not. We show that the role that this inequality plays in the spread of misinformation is highly complex. For instance, communities who hoard resources and deny them to the larger population can end up exposing themselves to more misinformation. Conversely, although more inequality generally leads to worse outcomes, the prevalence of misinformation in society is nonmonotone in the level of inequality. This implies that policies that decrease inequality without substantially reducing it can leave society more vulnerable to misinformation. This paper was accepted by Baris Ata, stochastic models and simulation. Supplemental Material: The data files are available at https://doi.org/10.1287/mnsc.2022.4376 .
An exploration of the development of resilience in student midwives
Authors: Williams Jacqui , Hadley Julie 
Published: April 2022

Background Resilience has been considered a key personal characteristic for a healthcare professional to be able to cope with the demands of their profession. There is a paucity of research that has considered resilience in midwifery and none has used a resilience scale over the length of the midwifery programme. Methods A resilience scale was used with one cohort of student midwives on five occasions throughout their midwifery programme. Results The mean across all of the five scale scores for the 15 participants was 122 (range of mean scores:92–135). The majority of participants (n=13) had average, moderate or moderately high resilience and all student midwives except one increased their resilience between the first and fifth completion of the scale. Conclusions The true resilience scale is a useful tool to use in midwifery undergraduate programmes to determine the development of resilience in student midwives. Importantly, the scale could be used at an early opportunity to identify any support needs.
Human amniotic fluid as a source of stem cells
Authors: Walentowicz Pawel , Sadlecki Pawel , Walentowicz-Sadlecka Malgorzata , Bajek Anna , Grabiec Marek , Drewa Tomasz 
Published: April 2022

Abstract
Human amniotic fluid collected during amniocentesis contains a heterogeneous population of differentiated and undifferentiated cells. Properties and number of these cells vary depending on the gestational age and the presence of potential fetal pathologies. The aim of this study was to analyze the effects of maternal, fetal, and environmental factors on the success rates of amniotic fluid stem cell cultures, the number of human amniotic fluid stem cells (hAFSC), their growth rates in primary cultures, and the number of cell passages. The study included 355 patients qualified for genetic amniocentesis at the Prenatal Genetic Unit, Department of Obstetrics, Gynecology and Oncologic Gynecology, Nicolaus Copernicus University Medical College in Bydgoszcz in 2011–2017. The mean age of the study participants was 34 ± 6.2 years, and mean gravidity amounted to 2.48 ± 1.4. Amniotic fluid sample volume turned out to be a highly significant (p < 0.01) predictor of culture success, and the relationship was particularly evident in women older than 40 years. Another highly significant predictor of culture success was the presence of two cell populations in the sample (p < 0.01). The likelihood of culture success correlated significantly (p < 0.05) with the season of the year at the time of amniocentesis. The number of cell passages differed significantly depending on the maternal age (p < 0.01). The number of passages also showed a highly significant relationship with the season of the year the sample was obtained (p < 0.01). Younger maternal age was identified as a determinant of high passage number (≥3), and another highly significant determinant of high passage number was the presence of two cell populations in the amniotic fluid sample (p < 0.01). Percentage of successfully established hAFSC cultures and the number of passages depended on amniotic fluid volume, the presence of two cell populations within the sample, and the season of the year. Individual characteristics of the donors, such as age and gravidity, did not exert a significant effect on the number of isolated hAFSCs and the rate of their growth. Patients’ place of residence, fetal karyotype, transportation time, and purity of the samples did not affect the success rates for primary cultures and the number of passages.
Aesthetic Cognitive Computing Clues of Materials Based on Multidimensional Perception
Authors: Zhou Xiaozhou , Bai Ruidong , Jin Yu , Xiao Weiye , Xue Chengqi 
Published: April 2022

Abstract
Based on the multidimensional visual perception of materials, the Kansei engineering method was employed to investigate the multidimensional perceptual strategy and the basis of aesthetic perception of materials. Solid wood and metal, common materials in interior environments that are closely related to health care, were used as material samples. The study was conducted on an online, self-developed collection, selecting more than 300 participants among designers and consumers with a mixed ratio of males to females to participate in the experiments. The first study screened out eight dimensions of material perception by visual semantic differences, selecting 80 metal materials and 14 solid wood materials for multidimensional perception tests. According to the test results, 12 metal materials and six solid wood materials were assigned systematically to 72 dual-material products to calculate the perceptual distance of each dimension among these materials. The results demonstrate that people have similar perception clue strategies in most perception dimensions between different materials. Regarding products with multiple materials, the perception of the materials on the main display surface has a more powerful influence on the overall product perception. The harmonious combination of materials will enhance health care in daily life. This article provides a possible cognitive clue on materials. The experimental results provide reference for medical product design.
Privacy Protection Scheme of Medical Electronic Health Records Based on Blockchain and Asymmetric Encryption
Authors: Huang Liang , Zhan Zhengyu , Lai Hua , Lee Hyung-Hyo 
Published: April 2022

Abstract
The current privacy protection scheme of medical electronic health records ignores the security of role interaction, which leads to low security of medical electronic health record data and a long time for data encryption and decryption. This paper proposes a privacy protection method of medical electronic health records based on blockchain and asymmetric encryption. This paper uses blockchain technology and asymmetric encryption algorithm to establish an electronic health record system model, selects the alliance chain to control the permissions of alliance members, constructs the corresponding sub key, uses shared users for information interaction, obtains the file key through verification (so as to decrypt the data and obtain the shared data plain text), and realizes medical electronic health through the privacy and protection scheme process of health records. Experimental results show that the data security of the proposed method is as high as 92 %, and the encryption and decryption time is only 0.45 s, which can effectively improve the data security and shorten the data encryption and decryption time.
An Improved Quality Inspection of Engine Bearings Using Machine Vision Systems
Authors: Vivek S. , Srinivasan K. , Sharmila B. , Dharshan Y. , Panchal Hitesh , Suresh M. , Ashokkumar R. , Sadasivuni Kishor Kumar , Elkelawy Medhat , Shrimali Neel 
Published: April 2022

Abstract
The growth of an industry is mostly based on the quality of the product. When there is a fault in the manufactured product in a batch, the entire batch is rejected because of a single faulty product. Quality has become one of the important factors deciding the growth of the industry. Industries nowadays are being automated in every phase of the manufacturing process. Here, an automated system is developed for the inspection of the product developed for the automobile industry. The bearing is one of the parts that play a major role in the connections with the engine and the shafts. Therefore, the bearing has to be perfect, as faulty bearings will lead to greater damage regardless of others. In the automated system, the bearing is inspected for the missing operations in the product. The faulty product is rejected and would be checked for rework or to be scraped. The inspected products are then being sent for the packing process. Through the automated inspection system, the production rate of the product can be increased, also increasing the reputation of the industry. The objective of the present work is to develop a machine vision system for quality inspection of bearing efficiency. The LabVIEW-based approach is carried out for the implementation in current research work.
Development of Test Instrument TIMSS Model to Measure Mathematical Ability VIII Grade Students
Authors: Adi Nur Romdlon Maslahul , Kartono Kartono , Susilaningsih Endang 
Published: April 2022

The teachers are still lack found practice tests that have characteristics such as the Trend in International Mathematics and Science Study (TIMSS) in Junior High School mathematics textbooks. This study aims to develop a TIMSS test instrument model that refers to the cognitive domain and the content domain for class VIII students. The respondents of this study were 5 people in the expert test, 10 people in the one to one test and 53 people in the small-scale test. This research is development research conducted following the development model of Borg & Gall. This step is only taken until the ninth step with a few modifications. Modifications are made by adding a one to one test copy from Tessmer. In content validity, as many as 5 items out of 35 items developed are not yet valid with a coefficient range of 0.6-0.79. Items were then revised to be tested in the small-scale test stage. One to one test results showed the instrument readability level was 81%. The validity test of the criteria shows a coefficient of 0.84 which means that the product developed is comparable to the original product. Interrater reliability was 0.661 and Alpha Chronbach reliability testing was a small scale at 0.854. The results showed that the instrument developed was valid in terms of content and criteria as well as reliable for use. The benefit of this research is that the developed test instrument can be used as a tool to measure the mathematics abilities of eighth-grade students.
Need Analysis for Development of a Cube and Beam Volume Assessment Instrument in Macromedia Flash Based Elementary Mathematics Learning
Authors: Aziz Khatmirul , Lestari Wahyu , Kustiono Kustiono 
Published: April 2022

The background of this study was that teacher has difficulty in overseeing the evaluation net, so that the potential for collaboration among students in evaluating was discovered, and the instruments used by teachers were still using classical assessment instruments. The purpose of this study was to determine the form of assessment instruments used by teachers in conducting evaluations, and to find out whether teachers need a Macromedia Flash-based research instrument handbook in evaluating learning. The sample used in the study was saturated or non-probability sampling where the sample was taken from SDN Bangetayu Wetan 02 class 5, the method used was quantitative and qualitative techniques, quantitative was used to calculate needs analysis and qualitative was used to collect data from samples, Data collection techniques used were using tests and non-tests where tests used cognitive assessment sheets and non-tests using data triangulation through collecting data, observations, interviews and documentation studies, the tools used were observation sheets, interview sheets, and documentation studies. The results obtained from the analysis of the needs of the cube and beam volume assessment instruments in learning Macromedia Flash based elementary school mathematics through the calculation of validity obtained Mean Square 0.956 and declared valid, as well as through the reliability test ebel obtained 0.414 so that it was declared reliable, so the needs analysis was declared valid and reliablethe development of cube and beam volume instruments in Macromedia Flash-based elementary mathematics learning is urgently needed. Manfat for the community is the community will better understand how important the use of Macromedia Flash application technology in the world of education, while for science to help overcome problems in the field of assessment.
Analysis of long-term temperatures inside tunnels during winter in Gangwon, South Korea
Authors: Chhun Kean Thai , Keo Sam-Ang , Jun Kyung-Jae , Yune Chan-Young 
Published: April 2022

Tunnels are among the main components of transport infrastructure systems and as such must be protected against damage. As damage is particularly prevalent in cold climates, tunnels in Gangwon province, the coldest region of South Korea, were investigated in this research. The temperatures inside three tunnels (one short tunnel and two medium-length tunnels) were measured during the winter season (November to March) using iButton sensors installed on the surface of the tunnel linings at a height of 2 m from the ground. The long-term temperature data measured in this way were analysed and the results showed that January was the coldest month. The minimum and maximum daily air temperatures most frequently appeared during 3–6 a.m. and 2–4 p.m., respectively. The highest temperature gradient was found to occur 30 m from the entrance or exit. The temperatures inside the tunnels were significantly affected by external wind induced by vehicle traffic volumes compared with the natural wind direction, the wind velocity and rainfall. It is concluded that tunnel damage caused by frost heave and freeze–thaw action can be reduced by frequent inspection and evaluation.