bluuebunny/crossref_metadata_2025_split huggingface dataset:
Redundante Punkthaltersysteme im Konstruktiven Glasbau durch hybride Verklebung
Authors: Offereins Dominik , Siebert Geralt 
Published: September 2022

AbstractDie Untersuchung von Klebverbindungen im Konstruktiven Glasbau stellt gegenwärtig ein sehr aktives Forschungsgebiet dar. Das Konzept der hybriden Verklebung bezieht sich dabei auf Punkthaltersysteme, die Fassadenverglasungen mit der tragenden Unterkonstruktion verbinden. Dabei wird durch die Kombination eines steifen Primärklebstoffs mit einem weicheren Sekundärklebstoff ein redundantes Tragverhalten erzeugt. Zur Untersuchung der generellen Machbarkeit des Systems wurden uniaxiale Zugversuche im gealterten und ungealterten Zustand an einem weichen strukturellen Silikonklebstoff und einem steifen Epoxidharzklebstoff durchgeführt. Mit den gewonnenen Versuchsdaten wurde zudem jeweils ein erstes Materialmodell in einer FEM‐Software erstellt.Redundant point‐fixings in structural glazing applications using hybrid bonding. The investigation of bonded joints in structural glazing is currently a very active field of research. The concept of hybrid bonding refers to point‐fixing systems that connect facade glazing to the steel substructure. A redundant load‐bearing behavior is created by combining a stiff primary adhesive with a softer secondary adhesive. To investigate the general feasibility of the system, uniaxial tensile tests were performed in the aged and unaged conditions on a soft structural silicone adhesive and a stiff epoxy resin adhesive. The test data obtained were also used to create an initial material model in FEM software in each case.
Isolierglasrandverbund auf beschichteten und digital bedruckten Glasoberflächen
Authors: Wünsch Jan , Wittwer Jost , Rumpf Alexander , Weller Bernhard 
Published: September 2022

AbstractDer Beitrag geht auf ausgewählte Ergebnisse des Forschungsvorhabens PRINTGLASS ein. Dieses Vorhaben widmet sich einer neuen Art der Randbedruckung. Die Randbedruckung wird im Digital‐druckverfahren direkt auf Glas oder auf ausgesuchten Sonnenschutzbeschichtungen ausgeführt. Der Einsatz der Digitalbedruckung als Haftgrund wurde durch eine neue Farbzusammensetzung und umfangreiche Untersuchungen möglich. Neben Untersuchungen an den digital bedruckten Oberflächen werden auch Ergebnisse zur Biegezugfestigkeit vorgestellt. Zusätzlich wurde das Haftvermögen verschiedener elastischer Dicht‐ und Klebstoffe im ungealterten und gealterten Zustand analysiert. Abschließend stellt der Beitrag noch die Dauerhaftigkeitsversuche an verschiedenen Isoliergläsern vor.Edge seal of insulating glass units on coated and digitally printed glass surfaces. The paper discusses selected results of the PRINTGLASS research project. This project is dedicated to a new type of edge printing. The edge printing is carried out in a digital printing process directly on glass or on selected sun protection coatings. The use of digital printing as a substrate was made possible thanks to a new ink composition and extensive research. In addition to tests on the digitally printed surfaces, results on bending tensile strength are also presented. In addition, the adhesion of various elastic sealants and adhesives in the unaged and aged state was analysed. Finally, the paper presents durability tests on various insulating glass units.
Towards Substrate–Reagent Interaction of Lochmann–Schlosser Bases in THF: Bridging THF Hides Potential Reaction Site of a Chiral Superbase
Authors: Brieger Lukas , Schrimpf Tobias , Scheel Rebecca , Unkelbach Christian , Strohmann Carsten 
Published: September 2022

AbstractThe metalation of N,N‐dimethylaminomethylferrocene in THF by the superbasic mixture of nBuLi/KOtBu proceeds readily at low temperatures to afford a bimetallic Li2K2 aggregate containing ferrocenyl anions and tert‐butoxide. Starting from an enantiomerically enriched ortho‐lithiated aminomethylferrocene, an enantiomerically pure superbase can be prepared. The molecular compound exhibits superbasic behavior deprotonating N,N‐dimethylbenzylamine in the α‐position and is also capable of deprotonating toluene. Quantum chemical calculations provide insight into the role of the bridging THF molecule to the possible substrate–reagent interaction. In addition, a benzylpotassium alkoxide adduct gives a closer look into the corresponding reaction site of the Lochmann–Schlosser base that is reported herein.
Using Numerical Dissipation Rate and Viscosity to Assess Turbulence‐Related Data Accuracy – Part 2: Results
Authors: Turek Vojtěch , Jegla Zdeněk , Dohnal Miloslav , Reppich Marcus 
Published: September 2022

AbstractThis is the second part of a two‐part paper focusing on the assessment of accuracy of turbulence‐related data from CFD simulations using effective numerical dissipation rate and effective numerical viscosity. Experimental setup has been discussed in the first part of this series. Here, the relevant solution data obtained via CFD are compared to the values from laser Doppler anemometry measurements, and it is studied whether the accuracy of such data can be assessed using the two mentioned quantities. The overall outcome is that although judging mesh quality generally is possible, alone the two quantities are insufficient to draw conclusions regarding the actual solution data.
Knowledge creation capability and the impact on innovation performance in global consulting firms: The role of human and social capital
Authors: Rhee Yang Pok , Park Chansoo , Cooper Tom 
Published: September 2022

AbstractThe purpose of this study is to identify the relationships between knowledge creation capability and innovation performance in multinational consulting organizations. We introduce two important but conceptually distinct, intellectual attribute constructs—human and social capital—as mechanisms that moderate the relationship. Survey data from 172 professional consultants in subsidiaries of multinational management consulting firms was empirically analyzed. This study confirms the importance of tacit knowledge creation capability for innovation and finds that explicit knowledge creation does not have substantial effects on innovation performance. Human capital has negative moderating effects on how tacit knowledge creation influences innovation performance, but it has a positive moderating effect on the relationship between explicit knowledge creation and innovation. The negative moderating effect of human capital appears stronger in the senior consultant groups. On the other hand, social capital has no moderating effects on knowledge creation capability and innovation. These results provide managerial implications for global subsidiaries' knowledge‐creating capabilities as drivers of successful, innovative change.
Barley grain protein is influenced by genotype, environment, and nitrogen management and is the major driver of malting quality
Authors: Halstead Margaret , Morrissy Campbell , Fisk Scott , Fox Glen , Hayes Patrick , Carrijo Daniela 
Published: September 2022

AbstractMalted barley (Hordeum vulgare) is a crucial component of beer, and it has been established that barley genotype has an effect on malting quality and beer flavor. This study extends this exploration by evaluating the effects of genotype, environment, and management on malting quality. Five fall‐planted malting barley lines were grown in three locations, each representing a distinct growing environment in the Pacific Northwest (United States), and under nitrogen (N) treatments: control (N1) and N application at heading in addition to the control (N2). Genotype × location interactions were observed for all agronomic (yield, test weight) and grain quality metrics (grain protein, plumpness), and N treatment × genotype interactions were observed for grain protein and plumpness. Overall, N2 increased grain protein, without exceeding specifications, by almost 1% point. Based on random forest analysis, the major driver of all‐malt index score was grain protein, followed by peak gelatinization temperature, germination energy, and water sensitivity. Still, over 70% of variation in all‐malt index score was unexplained, which is likely due to genotype and location differences, as indicated by principal component analysis. This research confirms the agronomic potential of fall‐planted malting barley in the Pacific Northwest and, although micromalted samples did not meet industry specifications, trends were identified that indicate the potential for these varieties at these locations. This research also demonstrates the potential of N management to fine‐tune malting quality through grain protein, and that malting quality is influenced by genotype and environment, though many of the specific drivers remain unknown.
Rational Design of Functional Electrolytes Towards Commercial Dual‐Ion Batteries
Authors: Jiang Hongzhu , Chen Zheng , Yang Yuanyuan , Fan Cheng , Zhao Jingwen , Cui Guanglei 
Published: September 2022

AbstractDual‐ion batteries (DIBs) based on anion (de)intercalation into low‐cost graphitic carbon cathodes hold great promise in grid‐scale energy storage. Different from the electrolyte in rocking‐chair batteries, which only serves as a charge transporter, both cations and anions in the electrolyte for DIBs participate in battery reactions. Hence, the impact of the electrolyte formulation on cycle life, energy density, as well as cost has become a subject of vital importance. This review discussed the challenges and recent progress of electrolytes for DIBs, with a particular focus on the exploration of electrolytes with high oxidation stability, high salt concentration, high ionic conductivity, and low cost. Moreover, the influence of varied ion concentrations at different state‐of‐charge levels on the electrolyte properties such as ionic conductivity and electrochemical stability is analyzed. Finally, perspectives on the current limitations and future research directions of electrolytes for DIBs are provided.
Is Pilates more effective and cost‐effective than aerobic exercise in the treatment of patients with fibromyalgia syndrome? A randomized controlled trial with economic evaluation
Authors: Franco Katherinne Ferro Moura , Miyamoto Gisela Cristiane , Franco Yuri Rafael dos Santos , Salvador Evany Maira Espírito Santo , do Nascimento Bruna Cristina Brajon , Menten Laura Alves , Cabral Cristina Maria Nunes 
Published: September 2022

AbstractBackgroundThe aim of this study was to assess the effectiveness and cost‐effectiveness of Pilates versus aerobic exercises in the treatment of patients with fibromyalgia syndrome from a societal perspective.MethodsThis two‐arm randomized controlled trial with blinded assessor and economic evaluation included 98 patients diagnosed with fibromyalgia syndrome using the American College of Rheumatology 2010 criteria, aged between 20 and 75 years, and pain intensity ≥3 points in the Pain Numerical Rating Scale. Patients were randomly allocated into the aerobic or Pilates group. Treatment was performed twice a week for 8 weeks. The primary outcome was the impact of fibromyalgia measured 8 weeks after randomization. Cost‐effectiveness and cost‐utility analyses were conducted for the impact of fibromyalgia and quality‐adjusted life‐years (QALYs), respectively, with a 12‐month time horizon.ResultsThere was no difference between the groups for the impact of fibromyalgia (MD: 6.5 points; 95% CI: −1.8 to 14.9). The incremental cost‐effectiveness ratio showed that 1‐point increase in the impact of fibromyalgia was on average associated with a societal cost of £56 for the Pilates group compared to the aerobic group. The cost‐utility analysis showed that the Pilates group had a 0.71 probability of being cost‐effective at a willingness‐to‐pay of £30,000 per QALY gained.ConclusionThere was no significant difference between groups for the impact of fibromyalgia. Pilates was not cost‐effective compared to aerobic exercises for the impact of fibromyalgia. However, Pilates seemed to be the preferred option of treatment considering QALYs, although it depends on the willingness‐to‐pay threshold.SignificancePilates showed to be a safe and effective alternative for the treatment of patients with fibromyalgia syndrome. Pilates presented similar results for the impact of fibromyalgia and superior results for pain relief compared to aerobic exercises, a highly recommended intervention for the treatment of fibromyalgia syndrome. Pilates was not cost‐effective compared to aerobic exercises for the impact of fibromyalgia. However, Pilates seemed to be a cost‐effective intervention for QALYs, depending on the decision‐maker's willingness‐to‐pay threshold.
Test–retest reliability of diffusion tensor imaging scalars in 5‐year‐olds
Authors: Rosberg Aylin , Tuulari Jetro J. , Kumpulainen Venla , Lukkarinen Minna , Pulli Elmo P. , Silver Eero , Copeland Anni , Saukko Ekaterina , Saunavaara Jani , Lewis John D. , Karlsson Linnea , Karlsson Hasse , Merisaari Harri 
Published: September 2022

AbstractDiffusion tensor imaging (DTI) has provided great insights into the microstructural features of the developing brain. However, DTI images are prone to several artifacts and the reliability of DTI scalars is of paramount importance for interpreting and generalizing the findings of DTI studies, especially in the younger population. In this study, we investigated the intrascan test–retest repeatability of four DTI scalars: fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD) in 5‐year‐old children (N = 67) with two different data preprocessing approaches: a volume censoring pipeline and an outlier replacement pipeline. We applied a region of interest (ROI) and a voxelwise analysis after careful quality control, tensor fitting and tract‐based spatial statistics. The data had three subsets and each subset included 31, 32, or 33 directions thus a total of 96 unique uniformly distributed diffusion encoding directions per subject. The repeatability of DTI scalars was evaluated with intraclass correlation coefficient (ICC(3,1)) and the variability between test and retest subsets. The results of both pipelines yielded good to excellent (ICC(3,1) > 0.75) reliability for most of the ROIs and an overall low variability (<10%). In the voxelwise analysis, FA and RD had higher ICC(3,1) values compared to AD and MD and the variability remained low (<12%) across all scalars. Our results suggest high intrascan repeatability in pediatric DTI and lend confidence to the use of the data in future cross‐sectional and longitudinal studies.
The business models employed by U.S. colleges & universities
Authors: Cardenas Artemio , Cheslock John 
Published: September 2022

AbstractThis chapter is intended for practitioners and scholars seeking to learn more about organizational finances. A hallmark of the U.S. higher education system is its heterogeneity. From research universities to community colleges, each institution seeks to excel in serving its respective mission. To do so, the institution must have a viable business model that ensures it generates sufficient revenue to offset expenditures. This article describes the business models currently used by different sectors of higher education, emerging threats to those business models, and the potential strategies that can be employed in response to those threats.
CD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis
Authors: Zhang Shaoying , Wan Dan , Zhu Mengchen , Wang Guihu , Zhang Xurui , Huang Na , Zhang Jian , Zhang Chongyu , Shang Qi , Zhang Chen , Liu Xi , Liang Fanfan , Zhang Chunyan , Kong Guangyao , Geng Jing , Yao Libo , Lu Shemin , Chen Yongyan , Li Zongfang 
Published: September 2022

Background and Aims:
Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression. The spleen serves as an extra monocyte reservoir in inflammatory conditions; however, the precise mechanisms of involvement of the spleen in the pathogenesis of liver fibrosis remain unclear.

Approach and Results:
By splenectomy and splenocyte transfusion, it was observed that splenic CD11b+ cells accumulated intrahepatically as Ly6Clo MoMFs to exacerbate CCl4‐induced liver fibrosis. The splenocyte migration into the fibrotic liver was further directly visualized by spleen‐specific photoconversion with KikGR mice and confirmed by CD45.1+/CD45.2+ spleen transplantation. Spleen‐derived CD11b+ cells purified from fibrotic livers were then annotated by single‐cell RNA sequencing, and a subtype of CD11b+CD43hiLy6Clo splenic monocytes (sM‐1s) was identified, which was markedly expanded in both spleens and livers of mice with liver fibrosis. sM‐1s exhibited mature feature with high expressions of F4/80, produced much ROS, and manifested preferential migration into livers. Once recruited, sM‐1s underwent sequential transformation to sM‐2s (highly expressed Mif, Msr1, Clec4d, and Cstb) and then to spleen‐derived macrophages (sMφs) with macrophage features of higher expressions of CX3CR1, F4/80, MHC class II, and CD64 in the fibrotic hepatic milieu. Furthermore, sM‐2s and sMφs were demonstrated capable of activating hepatic stellate cells and thus exacerbating liver fibrosis.

Conclusions:
CD11b+CD43hiLy6Clo splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. These findings reveal precise mechanisms of spleen–liver axis in hepatic pathogenesis and shed light on the potential of sM‐1 as candidate target for controlling liver diseases.
Definition of a tool to assess shared decision‐making (SDM) on women with breast cancer: A value‐based approach
Authors: Angioletti Carmen , de Mattia Egidio , Carloni Luca M. , Morsella Alisha , Fabi Alessandra , Orlandi Armando , Tortora Giampaolo , de Belvis Antonio G. 
Published: September 2022

AbstractBackground and AimsIn oncology, there is increasing talk of personalized treatment and shared decision‐making (SDM), especially when multiple treatment options are available with different outcomes depending on patient preference. The present study aimed to define the set of main dimensions and relative tools to assess the Value brought to patients from a Breast Cancer's Clinical pathway structured according to a dynamic SDM framework.MethodsStarting from our previous systematic review of the literature, a deep search of the main evidence‐based and already validated questionnaires was carried out. In the second phase, to corroborate this grid, a Delphi survey was conducted to assess each questionnaire identified for each dimension, against the following seven value‐based criteria: Clinical Benefit, Safety, Care Team Well Being, Patient Reported Outcomes Measures, Green Oncology, Impact on Health Budget, and Genomic Profile.ResultsThe resulting 7‐dimension questionnaire is composed of 72 questions. Of these, some quantitatively and objectively assess the evolution of the patient's disease state, whereas others aim to ask patients about their active involvement in decisions affecting them and to investigate whether they were free to explore their preferences. Furthermore, to frame the analyzed phenomenon at the right time, for each questionnaire section, the specific, evidence‐based timing of administration is indicated.ConclusionThe resulting questionnaire is validated in its entirety and it is composed of a set of questions and relative time point for data collections to assess the Value brought to patients undertaking a Breast Cancer's Clinical pathway, structured according to a dynamic SDM framework. It constitutes a quantitative instrument to integrate patient centeredness with a personalized perspective in the care management of women with breast cancer.
Low volume polyethylene glycol combined with senna versus high volume polyethylene glycol, which regimen is better for bowel preparation for colonoscopy? A randomized, controlled, and single‐blinded trial
Authors: Sadeghi Amir , Rahmani Khaled , Ketabi Moghadam Pardis , Abdi Saeed , Jahanian Ali , Fathy Mobin , Mohammadi Mahsa , Mahdavi Roshan Mehran , Olfatifar Meysam , Zali Mohammad Reza , Hatamnejad Mohammad Reza , Rajabnia Mohsen 
Published: September 2022

AbstractBackground and AimsBowel preparation affects the quality of colonoscopy. Reaching the optimal preparation has been a challenge for years. Polyethylene glycol (PEG) is the sole FDA‐approved substance for this purpose. However, patients find it unpleasant and often complain about its adverse effects. In this study, we aimed to reduce these complaints by lowering the amount of PEG and adding senna which is an herbal stimulant laxative.MethodsFour hundred and eighty‐six patients were admitted for colonoscopy. Finally, 382 patients were enrolled in the study and we divided them into two groups; 186 patients were placed in which conventional high volume PEG‐alone regimen was consumed and 196 patients in which low volume PEG plus senna regimen was offered. The quality of colon preparation was compared between the two groups by independent two samples t‐test (or its corresponding nonparametric test), Fisher's exact, or χ2 test in SPSS software version 22.ResultsThe colon preparation quality was equally efficient in the two groups as 69.36% in the high volume PEG group and 71.94% in PEG plus senna group had adequate bowel preparation (p = 0.58). Adverse effects, like nausea, bloating, headache, and sleeplessness were significantly less in the low volume PEG plus senna group.ConclusionBesides the fact that bowel preparation by low volume PEG plus senna combination was noninferior to the conventional high volume PEG‐alone regimen, the side effects were much less common with the low volume PEG plus senna regimen.
Compliance with standard precaution of infection prevention practice and associated factors among health care workers in Ethiopia: Mixed method study
Authors: Kassa Alebachew , Tadesse Sisay Eshete , Walelign Fasil , Kebede Natnael 
Published: September 2022

AbstractBackgrounds and AimsIn developing countries, most infections can be prevented with relatively inexpensive infection prevention methods. However, there is limited information on standard precautions for infection prevention practices among health workers in Ethiopia Therefore, this study aimed to assess the compliance with the standard precaution of infection prevention practice and associated factors among health care workers (HCWs) using a mixed method study.MethodsA hospital‐based mixed‐methods study design (concurrent mixed method design) was conducted among 378 randomly selected health professionals. Self‐administered questionnaire; an in‐depth interview and an observational checklist were used to collect the data. The collected data were cleaned and entered into Epi data and analyzed using a static package for social science. Descriptive statistics were conducted and the result was reported using frequency, and percentile. Logistic regression was performed to identify associated factors. Adjusted odds ratios with 95% confidence intervals (CIs) and p < 0.05 were used to explain statistically significant associations.ResultsThe proportion of standard precaution practice among HCWs at Dessie specialized and comprehensive hospital was 55.6% (put the 95% CI). Age ≤ 25 years (AOR = 0.13, 95% CI: [0.04, 0.42]) and age 31 years above age ≤ 31 years (AOR = 0.06, 95% CI: [0.02, 0.3]), positive attitude toward the standard precaution (AOR: 6.43, 95% CI: [3.47, 11.94]). Access to IP guidelines (AOR: 3.13, 95% CI: [1.61, 6.07]). Training on standard precautions (AOR: 3.61, 95% CI: [1.75, 7.48]) were factors associated with standard precaution practice.ConclusionsIn this study, the overall proportion of HCWs' compliance with standard preventive practice was low. HCWs aged 31 years and above, training on standard precaution practice, availability of guidelines in each ward, attitude toward standard precaution practice, knowledge about standard precaution practice, and accessibility of standard precaution supplies were associated with compliance to standard precaution practice. Therefore, the strategies should be designed to fulfill hospitals with supplies, training, and avail guidelines in each ward.