bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advance care planning engagement in patients with chronic, life-limiting illness: baseline findings from a cluster-randomised controlled trial in primary care
Authors: Stevens Julie , Miranda Rose , Deliens Luc , Pype Peter , De Vleminck Aline , Pardon Koen 
Published: November 2022

BackgroundAdvance care planning (ACP) has been characterised as a complex process of communication and decision making. For ACP behaviour change, underlying processes such as self-efficacy and readiness are needed. However, studies about which patient characteristics are associated with ACP have mainly focused on whether ACP actions are completed, leaving behaviour change processes unexplored.AimTo assess whether patients’ characteristics and patient-perceived quality of GP ACP communication were associated with patients’ ACP engagement.Design and settingBaseline data were used from the ACP-GP cluster-randomised controlled trial in patients with chronic, life-limiting illness (n= 95).MethodPatients completed questionnaires detailing demographic and clinical characteristics, and their perception about their GPs’ ACP information provision and listening. Engagement was measured using the 15-item ACP Engagement Survey, with self-efficacy and readiness subscales. Linear mixed models tested associations with engagement.ResultsDemographic and clinical characteristics were not associated with engagement; nor was how much ACP information patients received from their GP or the extent to which the GP listened to what was important for the patient to live well or important to the patient regarding future care. Higher overall ACP engagement (P= 0.002) and self-efficacy (P<0.001) were observed in patients who gave a high rating for the extent to which their GP listened to their worries regarding future health.ConclusionThis study suggests that GPs providing information about ACP alone is not associated with a patient’s ACP engagement; an important element is to listen to patients’ worries regarding their future health.
Home monitoring by pulse oximetry of primary care patients with COVID-19: a pilot randomised controlled trial
Authors: Smit Karin , Venekamp Roderick P , Krol Loeke A , Geersing Geert-Jan , Schoonhoven Lisette , Kaasjager Karin AH , Rutten Frans H , Zwart Dorien LM 
Published: November 2022

BackgroundPulse oximetry as a home or remote monitoring tool accelerated during the pandemic for patients with COVID-19, but evidence on its use is lacking.AimTo assess the feasibility of home monitoring by pulse oximetry of patients aged ≥40 years with cardiovascular comorbidity and moderate-to-severe COVID-19.Design and settingA primary care-based, open, pilot randomised controlled trial, with nested process evaluation, was undertaken in the Netherlands.MethodFrom November 2020 to June 2021, eligible patients presenting to one of 14 participating Dutch general practices were randomly allocated to regular measurement of peripheral oxygen saturation (at least three SpO2measurements per day for 14 days) with a validated pulse oximeter or usual care.ResultsAll 41 participants (21 intervention, 20 usual care) completed the 45-day follow-up period. Overall, the intervention group performed 97.6% of protocolised measurements; the median daily measurement per participant was 2.7 (interquartile range 1–4). Hypoxemia (SpO2<94%) was reported in 10 participants (in 52 measurements); of those, six consulted the GP as instructed. Participants reported a high feeling of safety (0–100 visual analogue scale): 71.8 for the intervention group versus 59.8 for the control (P= 0.09). Primary care consultations were similar across groups: 50 for the intervention versus 51 for the control. Eleven visits by 10 participants were made to the emergency department (eight from the intervention group versus three from usual care), of which six participants were hospitalised (five intervention versus one usual care). No participants were admitted to the intensive care unit or died during follow-up.ConclusionHome monitoring of patients with moderate-to-severe COVID-19 by pulse oximetry appeared feasible; adherence was high, patients reported a high feeling of safety, while the number of primary care consultations remained similar to usual care.
INTEGRATION OF DATA MINING METHODS DURING INFORMATION AND ANALYTICAL WORK
Authors: Панков А.В. , Багрецов С.А. , Лаута О.С. , Васильев Н.А. 
Published: November 2022

В статье представлен концептуальный подход к совершенствованию процессов информационно-аналитической работы при решении задач распознавания состояния частично наблюдаемых объектов управления. Основу предложенного подхода формирует способ агрегирования результатов неравноточного распознавания состояний объектов с использованием нескольких методов идентификации. Приводятся результаты эксперимента по оцениванию качества информационного решения при объединении результатов, полученных с использованием методов машинного обучения.
The article presents a conceptual approach to improving the processes of information and analytical work in solving problems of recognizing the state of partially observed control objects. The basis of the proposed approach is formed by the method of aggregating the results of non-precision recognition of the states of objects using several identification methods. The results of the experiment on evaluating the quality of an information solution by combining the results obtained using machine learning methods are presented.
Element-selective magnetization states in a Gd23Fe67Co10 alloy, probed by soft X-ray resonant magneto-optical Kerr effect
Authors: Sumi Toshihide , Senoo Tomoaki , Horio Masafumi , El Moussaoui Souliman , Nakamura Eiken , Tanaka Kiyohisa , Tsukamoto Arata , Matsuda Iwao 
Published: November 2022

Abstract
The core-level resonant magneto-optical Kerr effect of a ferrimagnetic metal alloy, Gd23Fe67Co10, was measured at the Fe M-shell and Gd N-shell absorption edges using rotating analyzer ellipsometry. A large Kerr rotation angle of several degrees was detected at room temperature. The signal was found to be strong enough for element-selective magneto-optical experiments to trace various magnetic events, such as all-optical magnetization switching.
Thermal neutron scintillation improvement in Ce:Li6Y(BO3)3 single crystals by thermal treatment
Authors: Yuan Dongsheng , Víllora Encarnación G , Kawaguchi Noriaki , Nakauchi Daisuke , Kato Takumi , Yanagida Takayuki , Shimamura Kiyoshi 
Published: November 2022

Abstract
The development of efficient, low-cost, and stable solid-state materials for portable thermal neutron detection is highly expected in order to substitute the currently used 3He and BF3 tank detectors. A few Li-based glasses and halide compounds have emerged as candidates, however, all of them present critical drawbacks for their practical implementations. Ce:Li6Y(BO3)3 is a priori a very promising oxide candidate that however has been disregarded so far due to its negligibly low light yield, caused by a poor crystalline and optical quality. In this study, we demonstrate that a post-growth thermal treatment is the key parameter to drastically reduce the concentration of intrinsic defects and scattering centers that lead to severe non-radiative recombination of excited electrons. Even though this annealing step also involves the oxidation of activator Ce3+ ions to Ce4+, a drastic enhancement of the light yield by ∼600% is achieved independently of the Ce3+ concentration within the considered range. The obtained light yield of 4650 ph n−1 is already close to that of reference Li-glass (commercial GS20 with 6000 ph n−1). An additional improvement can be envisaged upon further optimization of the Ce3+ concentration and the annealing time, so that Ce:Li6Y(BO3)3 reaches a light yield comparable to the state-of-the-art one for thermal neutron detection.
Pengaruh Current Ratio Terhadap Harga Saham dengan Price to Book Value sebagai Variabel Intervening pada Perusahaan Terklasifikasi SIC-3711 yang Terdaftar di NYSE Periode 2016 - 2020
Authors: Wibowo Agus Adi , Nurhasanah Nunung , Supriyadi Didit 
Published: November 2022

Abstract–This study aims to determine the effect of Current Ratio (CR) on Stock Prices with Price to Book Value (PBV) as an intervening variable in standard industry classification companies SIC-3711 listed on the NYSE in the 2016 – 2020 research period. The data used in this study is secondary data obtained from the NYSE website and the company's annual report. The research method uses descriptive verification. The sampling technique in this study uses purposive sampling so that a sample of 7 companies is obtained from a total of 18 companies registered in similar industry classification. Data processing uses Path Analysis using statistical product and services solution (SPSS) software version 25. The results show that Current Ratio (CR) with Price to Book Value (PBV) as an intervening variable has a significant effect on stock prices.
Abstrak–Penelitian ini bertujuan untuk mengetahui pengaruh Current Ratio (CR) terhadap Harga Saham dengan Price to Book Value (PBV) sebagai variabel intervening pada perusahaan klasifikasi industry standar SIC-3711 yang terdaftar di NYSE pada periode penelitian 2016 – 2020. Data yang di gunakan pada penelitian ini merupakan data sekunder yang diperoleh dari laman NYSE serta laporan tahunan perusahaan. Metode penelitian menggunakan deskriptif verifikatif. Teknik sample pada penelitian ini menggunakan purposive sampling sehingga di peroleh sampel sejumlah 7 perusahaan dari total 18 perusahaan yang terdaftar pada klasifikasi industry sejenis sejenis. Pengolahan data menggunakan Path Analysis dengan menggunakan aplikasi software statistical product and services solution (SPSS) Versi 25. Hasil penelitian menunujukkan bahwa Current Ratio (CR) dengan Price to Book Value (PBV) sebagai variabel intervening berpengaruh signifikan terhadap Harga Saham
The Metallicity and Distance of NGC 2403 from Blue Supergiants
Authors: Bresolin Fabio , Kudritzki Rolf-Peter , Urbaneja Miguel A. 
Published: November 2022

Abstract
We present the first quantitative spectral analysis of blue supergiant stars in the nearby galaxy NGC 2403. Out of a sample of 47 targets observed with the LRIS spectrograph at the Keck I telescope we have extracted 16 B- and A-type supergiants for which we have data of sufficient quality to carry out a comparison with model spectra of evolved massive stars and infer the stellar parameters. The radial metallicity gradient of NGC 2403 that we derive has a slope of −0.14(±0.05) dex

r

e

−
1

, and is in accordance with the analysis of H ii region oxygen abundances. We present evidence that the stellar metallicities that we obtain in extragalactic systems in general agree with the nebular abundances based on the analysis of the auroral lines, over more than 1 order of magnitude in metallicity. Adopting the known relation between stellar parameters and intrinsic luminosity we find a distance modulus μ = 27.38 ± 0.08 mag. While this can be brought into agreement with Cepheid-based determinations, it is 0.14 mag short of the value measured from the tip of the red giant branch. We update the mass–metallicity relation secured from chemical abundance studies of stars in resolved star-forming galaxies.
Light Curve Analysis of Nine Algol (EA) Eclipsing Binaries Discovered During the Dauban Survey-additional Data
Authors: Hinzel David H. 
Published: November 2022

Abstract
The Research Note entitled Light Curve Analysis of Nine Algol (EA) Eclipsing Binaries Discovered During the Dauban Survey produced composite light curves for each of the nine systems. This analysis identified specific periods, eclipse durations, Johnson V and Sloan g photometric magnitude ranges, and system temperatures. Also in that Research Note the light curves for four of the nine binary systems were presented (V242, V243, V244, and V247). This Research Note presents light curves for the remaining five eclipsing binary systems (V239, V240, V241, V245, and V246).
M31N 2017-01e: Discovery of a Previous Eruption in this Enigmatic Recurrent Nova
Authors: Shafter Allen W. , Taguchi Kenta , Zhao 赵 Jingyuan 经远 , Hornoch Kamil 
Published: November 2022

Abstract
We report the discovery of a previously unknown eruption of the recurrent nova M31N 2017-01e that took place on 2012 January 11. The earlier eruption was detected by Pan-STARRS and occurred 1847 days (5.06 yr) prior to the eruption on 2017 January 31 (M31N 2017-01e). The nova has now been seen to have had a total of four recorded eruptions (M31N 2012-01c, 2017-01e, 2019-09d, and 2022-03d) with a mean time between outbursts of just 929.5 ± 6.8 days (2.545 ± 0.019 yr), the second shortest recurrence time known for any nova. We also show that there is a blue variable source (〈V〉 = 20.56 ± 0.17, B − V ≃ 0.045), apparently coincident with the position of the nova, that exhibits a 14.3 days periodicity. Possible models of the system are proposed, but none are entirely satisfactory.
Cuestiones de práctica de Geometría y de Goniometría para el trazado de la orientación en los cenobios hispánicos (siglos IX-XII)
Authors: Lluis i Ginovart Josep , Lluis-Teruel Cinta 
Published: November 2022

La primera operación de un edifico sacro cristiano es su orientación. Las liturgias (s. IX-XII) determinan una alineación (E-O), la precisión de algunas iglesias, con Az muy próximo a 90º y con una altura del horizonte (ASS) > 0º, indican la utilización de métodos geométricos, entre los que se encuentra el de Gisemundo (c.800) del monasterio de Ripoll (ACA 106), considerado más preciso que los vitruvianos por la sencillez de su trazado equinoccial. Pese a ello, hay implícitamente unos conocimientos goniométricos para determinar la proporción entre el gnomon y la sombra, relacionados con los horologium pedum (IX-XII) y los posteriores relojes de sol azimutales como el de Ripoll (ACA 225) (s. XI). Para la latitud de Gisemundo, su método, permite en los equinoccios, trazar con gran precisión el enfilamiento equinoccial, con un gnomon de proporción [2/3], con una sombra [1], próxima a las horas (III-IX).
Flexión activa en forjados construidos con contrachapado curvado en el plano
Authors: García Santarbárbara Alfonso , Monjo Carrió Juan , Sakata Hiroyasu , Sastre Sastre Ramón 
Published: November 2022

Las estructuras con flexión activa incorporan vigas o superficies curvas que obtienen esa geometría mediante deformación elástica de elementos originalmente rectos o planos. Cuando se emparejan elementos curvos y rectos se pueden conseguir sistemas con una rigidez mayor que si trabajan independientemente. En este trabajo se estudian los efectos de la flexión activa en doce propuestas de forjado con viguetas construidas a partir de elementos curvos y rectos de contrachapado de lauan. Estas soluciones se analizan informáticamente y se comparan con la solución de referencia de viguetas rectas y paralelas en un diagrama Bic-λ, el instrumento ideado por Frei Otto para comparar el consumo material de distintos sistemas estructurales. Simultáneamente al estudio analítico se realizan ensayos a flexión de tres puntos de dos prototipos a escala real. Las conclusiones derivadas de los ensayos servirán para introducir un nuevo caso de vigueta con más elementos que acabará siendo el más eficiente.
Prostate-specific membrane antigen expression in clear-cell renal cell carcinoma
Authors: Abd El Khalek Safaa M.M. , Hafez Fatma S. 
Published: November 2022

Background
Clear-cell renal cell carcinoma (ccRCC) represents the majority of renal neoplasms with usual late presentation. Metastasis of ccRCC is very common owing to the vascular nature of this tumor. Identifying markers that could predict tumor behavior and metastatic potential is crucial to improve patient prognosis. Prostate-specific membrane antigen (PSMA) is a recently identified vascular marker that is expressed in many cancer types. This study aimed at evaluation of its clinicopathologic role in ccRCC.

Materials and methods
A total of 40 cases of ccRCC were recruited and subjected to immunohistochemical staining for PSMA. Statistical analysis was performed to assess its expression and its relationship with different clinicopathologic parameters.

Results
PSMA expression was positive in 72.5% of all cases. High expression was detected in 52.5% of cases, with positive correlation with high tumor grade (P=0.01), stage (0.04), and lymphovascular invasion (P=0.03). PSMA expression was positive in 83.3% of cases of tumor thrombus tissue, and 50% of these cases showed high expression. Two (50%) cases of metastatic lesions showed low positive expression for PSMA with high PSMA expression in 75% of the corresponding primary lesions.

Conclusion
PSMA is specifically expressed in the vasculature of ccRCC, showing a positive correlation with poor prognostic parameters. This renders PSMA as a promising prognostic marker and therapeutic target.
Overview of statistical methods usage in Indian anaesthesia publications
Authors: Tyagi Asha , Garg Devansh , Mohan Aparna , Salhotra Rashmi , Vashisth Ishita , Agrawal Ananya , Deshpande Sanika , Deep Sonali , Das Sacchidananda , Malhotra Rajeev K , Pradhan Rajeev , Panda Aparajita 
Published: November 2022

Background and Aims:
Despite the importance of statistics being well established for medical research, it remains a neglected area of understanding and learning. The present survey aimed to examine the use of various statistical methods in a two-year sample (2019–2020) of representative Indian anaesthesia journals and compare it with an international top-ranked journal.

Methods:
The literature survey included analysis of 748 original articles from ‘Indian Journal of Anaesthesia’ (179), ‘Journal of Anaesthesiology Clinical Pharmacology’ (125) and ‘Anesthesia & Analgesia’ (444) published over the period. Original research articles were identified from the table of contents of each issue. Articles were assessed for statistical methods, categorised as being descriptive, elementary, multivariable, advanced multivariate or diagnostic/classification.

Results:
Compared to Anesthesia & Analgesia, the Indian journals (considered together) had a significantly greater use of mean (standard deviation) (91.2% versus 70%) and percentages (79.5% versus 67.6%) (P = 0.000 each); and lesser for Wilcoxon (5.4% versus 14.6%) and Pearson/Spearman (5.1% versus 13.5%) correlation tests (P = 0.000 each), multivariable tests including various regression methods (P < 0.001), classification/diagnostic tests [Receiver operating characteristic (ROC) curve analysis, P = 0.022; sensitivity/specificity, P = 0.000; precision, P = 0.006; and relative risk/risk ratio, P = 0.010] and a virtual absence of complex multivariate tests.

Conclusion:
The findings show limited use of advanced complex statistical methods in Indian anaesthesia journals, usually being restricted to descriptive or elementary. There was a strong bias towards using randomised controlled designs. The findings suggest an urgent and focussed need on training in research methodology, including statistical methods, during postgraduation and continued medical training.
Effect of sevoflurane versus desflurane on blood glucose level in patients undergoing intracranial neurosurgery: A randomised controlled study
Authors: Kaushal Ashutosh , Bindra Ashish , Dube Surya Kumar 
Published: November 2022

Background and Aims:
Anaesthetic agents can affect the neuroendocrine response to surgical stress. Along with affecting other parameters, this can affect blood glucose levels. This study aimed to compare the effect of sevoflurane and desflurane on hourly intraoperative blood glucose levels in non-diabetic patients undergoing intracranial surgery.

Methods:
A total of 70 adults (18–65 years) of American Society of Anesthesiologists physical status I and II undergoing elective intracranial surgery for supratentorial and infratentorial lesions were enroled. Patients were randomised to receive either sevoflurane or desflurane as the maintenance anaesthetic agent. The blood glucose level was measured hourly after induction until the completion of surgery. Parametric tests, non-parametric tests, Friedman test, generalised estimating equations, Chi-square test, and Fisher’s exact test were used to analyse the data.

Results:
In the sevoflurane group, the mean (standard deviation) blood glucose (mg/dL) increased from 93.34 (9.33) at the baseline to a maximum of 102.00 (8.61) at the 9 hours timepoint. This change was statistically significant (P < 0.001). In the desflurane group, the mean blood sugar (mg/dL) increased from 89.34 (9.85) at the baseline to a maximum of 92.37 (9.92) at the 4 hours timepoint and then decreased to 88.50 (0.71) at 9 hours timepoint.

Conclusion:
Desflurane caused an initial rise followed by a decline, whereas a gradual increase in intraoperative blood glucose level was seen with sevoflurane use in non-diabetic adult patients undergoing elective neurosurgery. The intraoperative change in blood sugar was statistically significant but was within the normal clinical range.
Malignant transformation in low-grade astrocytoma for long-term monitoring
Authors: Tunthanathip Thara 
Published: November 2022

Background:
Malignant transformation (MT) of low-grade astrocytoma (LGA) produces a poor prognosis in benign tumors. Currently, variables linked with MT of LGA have proven equivocal. The present study aims to evaluate the risk variables, indicating that LGA gradually differentiates to malignant astrocytoma.

Methods:
Retrospective cohort analysis of LGA patients was performed. Both univariate and multivariate studies were used to discover variables connected to MT using the Cox regression method. As a result, the cumulative incidence of MT for each covariate survival curve was built after the final model.

Results:
In the current study, 115 individuals with LGA were included in the analysis, and MT was found in 16.5% of cases. In the case of MT, 68.4% of patients progressed to glioblastoma, whereas 31.6% progressed to anaplastic astrocytoma. Significant factors included supratentorial tumor (hazard ratio (HR) 3.41, 95% CI 1.18–12.10), midline shift > 5 mm (HR 7.15, 95% CI 2.28–34.33), and non-total resection as follows: subtotal resection (HR 5.09, 95% CI 0.07–24.02), partial resection (HR 1.61, 95% CI 1.09–24.11), and biopsy (HR 2.80, 95% CI 1.18–32.52).

Conclusion:
In individuals with LGA, MT dramatically altered the disease's natural history to a poor prognosis. The present study's analysis of the clinical features of patients indicated supratentorial LGA, a midline shift greater than 5 mm, and the degree of resection as risk factors for MT. The more extensive the resection, the greater the reduction in tumor load and MT. In addition, more molecular study is necessary to elucidate the pathophysiology of MT.