bluuebunny/crossref_metadata_2025_split huggingface dataset:
Epileptic encephalopathy caused by 1p36 deletion: literature review and case series
Authors: Bobylova M. Yu. , Konurina O. V. , Borovikova N. A. , Chadaev V. A. 
Published: September 2022

1p36 deletion syndrome (OMIM: 607872) is an autosomal dominant disease caused by a terminal deletion of the short arm of chromosome 1, characterized by specific craniofacial dysmorphism, delayed speech development and epilepsy. The severity of epilepsy is related to the size of the mutation.Objective: to study the clinical and electroencephalographic picture of the disease.We have analyzed 3 cases (male patients from 2 to 6 years old), including anamnesis of life and disease, electroencephalography data in dynamics and genetic analysis data.All three patients are united by a combination of epilepsy, mental retardation and cerebral palsy-like movement disorders. The epilepsy manifestations varied from severe with absolutely pharmacoresistant epileptic spasms (cases 1 and 2) to mild course with febrile seizures only (case 3). This is probably due to the presence of a shorter mutation in patient 3. Cases 1 and 2 had epileptic encephalopathy, epilepsy with continuing epileptiform discharges on the EEG and a gross delay in speech and mental development. These patients could not speak and not understand the speech addressed, do not follow instructions. Patient 3’ self-care and play activities are developed by age, speech understanding is fully formed, but there is a complete absence of expressive speech.1p36 deletion syndrome is a developmental and epileptic encephalopathy.
An Inter digital- Poison Ivy Leaf Shaped Filtenna with Multiple Defects in Ground for S-Band bandwidth Applications
Authors: Sarma Ch. Amarnatha , Inthiyaz Syed , Madhav B T P , Lakshmi P Sree 
Published: September 2022

The proposed work, a filtenna for s band application is implemented. It is designed by embedding an Interdigital band pass filter (IDBPF) and leaf shaped antenna which are operated in S band. The IDFBPF is having seven resonators with one end shorted through dual vias. It offers a bandwidth of 1.3GHz from 1.65GHz to 2.95GHz. A Dumbbell shaped DGS (Defected Ground Structure) provided in ground to improve the filter characteristics. Measured pass (BRL) band return loss (S11) & insertion loss (S12) are -18dB & -4.6dB correspondingly. Further, leaf shaped antenna is designed based on modified polar transformation equation; it has 2.7 GHz bandwidth from 1.3 GH to 3 GHz and has a gain of -5.45dBi, and return loss (S11) of -19.5 dB. The filtenna is obtained by integrating the IDBBPF in the fodder line of the leaf designed antenna. The final model has 1.2 GHz operating bandwidth from 02.30 GHz to 03.50 GHz with peak arrival damages at 2.4GHz and 3.1GHz with -20dB and-24dB respectively. The designed filtenna has a pass band gain of -5.3dBi. The shift in operating band is due to combining the filter with antenna. The proposed model is invented on FR4 substrate having a wideness of 01.60 mm and having a dimension of 0.25 0.58 ?02. In this final model two complementary slip ring resonators (CSRR) are used in addition with four dumbbell structures as defects in the ground plane to avoid ripples in return loss (S11) graph. A high degree of concordance exists between empirically measured and simulated outcomes. The radiation band is showing its application in S band wireless mobile communications, Wi-Fi and ISM 2.4GHz band.
A comparative study of shear bond strength of four different light cure orthodontic adhesives: An in vitro study
Authors: Prasad Raghu Ranjan , Rai Swati , Jain Abhay Kumar , Sahu Anshu , Lall Rajeev , Thakur Sneha 
Published: September 2022

To compare the shear bond strength and Adhesive Remnent Index (ARI) of metal brackets using four different bonding systems: Heliosit Orthodontic Bonding Material (Ivoclar Vivadent), Ormco Enlight Light Cure Adhesive, Transbond XT Light Cure Adhesive (3M UNITEK) and Light cured Orthofix (Anabond Stedman Pharma Research (P) Ltd. In the present study 120 extracted sound human upper bicuspids were taken and divided into four groups. Group 1: Heliosit Orthodontic Bonding Material (Ivoclar Vivadent), Group 2 : Ormco Enlight Light Cure Adhesive ,Group 3: Transbond XT Light Cure Adhesive(3M UNITEK) and Group 4: Light cured Orthofix (Anabond Stedman Pharma Research (P) Ltd. In all the groups (n = 120) orthodontic metal brackets were bonded with the four different light cure adhesives respectively and all the samples were evaluated for shear bond strength using Instron(3366) universal testing machine at a cross speed of 1 mm/min. The bracket failure mode was examined using Adhesive Remnant Index (ARI). The Inter group comparison (&#62;2 groups) was done using one way ANOVA followed by pair wise comparison using post hoc test. Comparison of frequencies of categories of variables with groups was done using Chi square test. For all the statistical tests, p&#60;0.05 was considered to be statistically significant, keeping α error at 5% and β error at 20%, thus giving a power to the study as 80%.: It was concluded that the mean shear bond strength of the Transbond XT was highest among the four adhesives studied. However all the adhesives tested exhibits adequate bond strength for clinical use and ARI scores was nearly same for the Transbond and Enlight adhesives studied.
“Bel Ağrısı” ile İlgili Türkçe İnternet Kaynaklı Hasta Eğitim Materyallerinin Okunabilirliklerinin Değerlendirilmesi
Authors: ÖZDURAN Erkan 
Published: September 2022

Amaç: Sağlık ile ilişkili bilgilere ulaşmak için internet kullanımı günden güne artmaktadır. Ancak bu bilgilerin güvenilirliği ve anlaşılırlığı üzerinde endişeler bulunmaktadır. Çalışmamızda bel ağrısı ile ilgili internet kaynaklı Hasta Eğitim Materyallerinin (HEM) okunabilirliğini, güvenilirliğini ve kalitesini araştırmayı amaçladık.
Gereç ve Yöntem: 26 Şubat 2022’de Google arama motorunda “Bel ağrısı” terimi aratılarak çalışma için uygun ilk 100 internet sitesi tespit edildi. İnternet-sitelerinin okunabilirlikleri Ateşman okunabilirlik formülüyle değerlendirildi. İnternet-sitelerinin güvenilirlikleri “Journal of the American Medical Association (JAMA) Benchmark” kriter skoru ile, kalite değerlendirmesi DISCERN skoru ve “Health on the Net Foundation code of conduct (HONcode)” varlığı ve popüleritesi ise ALEXA ile değerlendirildi.
Bulgular: Çalışmamızda metin bölümleri incelendiğinde ortalama Ateşman okunabilirlik skorunun 61,09±7,31 (orta güçlükte) olduğu tespit edilmiştir. JAMA skorları ortalama değeri 1,46±0,91 (düşük güvenilir) ve internet sitelerinin %12’si yüksek güvenilir tespit edilmiştir. Ortalama DISCERN skoru 34,08±11,74 (kötü kalite) tespit edilmiştir. %17 internet sitesinde HONcode varlığı tespit edilmiştir. İnternet sitelerin kaynakları ile güvenilirlik ve kalite skorları arasında istatistiksel olarak anlamlı farklılık tespit edilmemiştir (p>0,05).
Sonuç: Bel ağrısı ile ilişkili Türkçe internet kaynaklı HEM’nin okunabilirlik düzeyinin orta güçlükte olduğu, düşük güvenilirlik ve kötü kalite içerdiği saptandı. İnternet siteleri hazırlanırken internet kaynaklı HEM’nin halkın eğitim düzeyine uygun okunabilirlik derecesine ve güvenilir içeriğe sahip olması gerektiğini düşünmekteyiz.
Kurşun Endüstrisi Çalışanlarında Osteoporoz Riski: Olgu Sunumu
Authors: HASANLI Yusuf Samir 
Published: September 2022

İnsanlar için toksik element olan kurşun, mesleki ve çevresel maruz kalma sonucu vücutta birden fazla organ sistemini etkileyebilir. Bunlardan biri de en fazla depolandığı ve mineralizasyonunu bozduğu yer olan kemik korteksidir. Sekonder osteoporozun hipertiroidizm, hipogonadizm, diyabetes mellitus, ilaçlar, otoimmun hastalıklar gibi bilinen birçok sebebi mevcuttur. Osteoporozun tarama ve teşhisinde çift enerjili X-ışını absorbsiyometrili kemik mineral dansitometre (KMD) yöntemi kullanılmaktadır.
Olgu: Otuz yaşında, evli, iki çocuklu erkek hasta. Beş yıldır bir akü üretim şirketinde beden işçisi olarak çalışmakta. İşe başladıktan bir yıl sonra ölçülen kan kurşun düzeyleri yüksek seyretmekte (>40 µg/dL). Hastanın bir yıl arayla çekilen kemik mineral dansitometresinde osteopeniden osteoporoza dönüşüm (femur boynu T skoru; -1,5’ten -2,78’e) izlendi. Sekonder osteoporoz nedenleri dışlandıktan sonra hasta kurşun maruziyetine bağlı osteoporoz olarak kabul edildi. Kurşundan korunma önerilerinde bulunuldu, osteoporoz için takip ve tedaviye alındı.
Kurşun endüstrisinde çalışan işçiler çeşitli yollarla kurşun maruziyeti yaşamaktadır. Birincil koruma yöntemlerinin alınması ile birlikte bu metalin kemik mineralizasyonunu bozma riski nedeniyle, çalışanların ikincil osteoporoz açısından periyodik olarak tarama ve tetkiki gerekebilir.
Some features of auditory nerve action potential recording in patients with cochlear implants
Authors:   Saint Petersburg Institute of Ear, Throat, Nose and Speech,  Saint Petersburg, 190013, Russia, Pudov V. I. , Pudov N. V. ,   Parent Association „I hear the world“, Saint Petersburg, 195299, Russia
Published: September 2022

Recording of auditory nerve action potential is now widely used in clinical practice to objectively adjust speech processor parameters in patients with cochlear implants. According to some authors, the correlation coefficient between the potential of the auditory nerve and the most comfortable level varies within a fairly wide range, but nevertheless it well determines the relief of the tuning curve. This article discusses the relationship of this correlation to the rate of growth of the response amplitude of the auditory nerve potential. Patients with high growth rate of auditory nerve potential amplitude show high correlation (R = 0,71) of this threshold with maximum comfortable level of auditory perception, but patients with low speed show low correlation (R = 0,34) of this dependence. In the latter case, the automatic mode of recording the auditory nerve potential does not achieve the desired result and requires the use of the visual analysis mode of the obtained results. In this case, it is necessary to create several progressive maps with subsequent verification of the results on the patient's behavioral reactions. The paper also presents a variety of options for recording the effect potential of the auditory nerve in special groups of patients with an anomaly of the cochlear and auditory nerve.
Treatment of Chronic Dislocated Patella in a Skeletally Mature Down Syndrome Patient
Authors: Fong Jiawen , Zeng Gerald Joseph , Lee Kong Hwee 
Published: September 2022

Case:
A 55-year-old man with Down syndrome (DS) suffered from chronic irreducible right patellar dislocation. Imaging studies showed an attenuated appearance of the medial patellar retinaculum, and the tibial tubercle to trochlear groove distance measured 1.6 cm. Right medial patellofemoral ligament reconstruction (MPFLR) and lateral lengthening (LL) with proximalization of the tibial tubercle (PTT) were performed with good surgical outcomes.

Conclusion:
The combination of MPFLR, LL, and PTT is a viable option for treating a skeletally mature DS patient with patellofemoral instability causing recurrent patellar dislocation.
Improvement of Knee Alignment and Function After Corrective Surgery for Hindfoot Deformity
Authors: Etani Yuki , Hirao Makoto , Ebina Kosuke , Noguchi Takaaki , Okamura Gensuke , Tsuboi Hideki , Miyama Akira , Tsuji Shigeyoshi , Kunugiza Yasuo , Okada Seiji , Hashimoto Jun 
Published: September 2022

Case:
Marked varus or valgus hindfoot deformities in 3 patients with ankle osteoarthritis or rheumatoid arthritis were treated by corrective surgery using total ankle arthroplasty or distal tibia oblique osteotomy. All cases achieved not only sufficient correction and satisfactory clinical/radiographic hindfoot improvement but also improvements in both knee alignment and function.

Conclusion:
Corrective surgery for hindfoot deformity can potentially change or improve ipsilateral knee alignment and function, representing an unexpected benefit of hindfoot realignment.
Distal Clavicle Autograft Fixed with Buttons for the Management of Shoulder Instability with Glenoid Defect
Authors: Anakwenze Oke 
Published: September 2022

Update
This article was updated on May 25, 2022, because of a previous error in the abstract and in the second paragraph of the paper. In the abstract, the sentence should read, “In this case report, we presented the case of a 39-year-old male lawyer who presented to our tertiary care clinic with recurrent instability of his left shoulder and significant glenoid bone loss.” In the second paragraph, the sentence should read, “In this case report, we presented the case of a 39-year-old man who presented to our tertiary care clinic with recurrent instability of his left shoulder and significant glenoid bone loss.”
An erratum (JBJS Case Connect. 2022;12[2]:e22.00001ER) has been published for this article.

Case:
In this case report, we presented the case of a 39-year-old male lawyer who presented to our tertiary care clinic with recurrent instability of his right shoulder and significant glenoid bone loss. This patient was treated with arthroscopic glenoid bone augmentation with his distal clavicle fixed with arthroscopic suture buttons.

Conclusion:
Use of a distal clavicle autograft with arthroscopic fixation using buttons is a novel and promising solution for the management of patients with shoulder instability and associated glenoid bone loss.
Exogenous Silicon Applications Enhance Peach Seedling Response to Flooding-Induced Hypoxia Stress
Authors: Clavijo-Herrera Jonathan , Shahid Muhammad Adnan , Rossi Lorenzo , Sarkhosh Ali 
Published: September 2022

AbstractPeach trees are highly susceptible to hypoxic conditions during flooding, which causes oxidative damage in plant cells, resulting in death. Silicon (Si) has been reported to improve plants’ performance under abiotic stresses, such as flooding. This study aimed to evaluate the performance of peach rootstock (‘MP-29’) seedlings under hypoxic stress. Seedlings were foliar sprayed with two levels (1000 and 1500 ppm) of silicon dioxide nanoparticles (SiNPs) and silicon dioxide solution (SiSol) to determine their capacity to mitigate oxidative damage. Seedlings treated with SiNPs had significantly higher antioxidant activities (superoxide dismutase, peroxidase, and catalase), and accumulation of compatible solutes (proline and glycine betaine) compared to those treated with SiSol and control seedlings. The rate of lipid peroxidation and generation of reactive oxygen species (ROS) O2and H2O2was higher in flooding stressed seedlings as compared to control seedlings; however, Si applications reduced those differences. SiNPs were more effective than SiSol in lowering the rate of lipid peroxidation and formation of ROS. In addition, Si applications to seedlings under non-hypoxic conditions aided to increase N, P, K, and Zn contents in leaves, compared to hypoxic-stressed and control seedlings, particularly when using 1500 ppm. Micronutrient content (Fe and Mn) was high in flooding-stressed seedlings, but SiNPs limited their concentration to levels lower than those in SiSol treated seedlings. In conclusion, Si applications improved the performance of peach seedlings exposed to flooding conditions. Additionally, SiNPs were more effective than SiSol in improving the adaptative stress response of peach seedlings to flooding stress.
On The Quality of Direct Assessment Methods Through the Effective Learning Outcomes to Align Institutional Programs Towards the Required Institutional Accreditation
Authors: ELmuTAz ElBerIer , elamin Khalid Abd el mageed hag , Nasry Nada Khalid El , Sara Elmekkawi , Sawsan AlMekawi 
Published: September 2022

Abstract
This paper focuses on the numerical weight calculations for a given learning outcome related to electrical engineering program courses at the University of Science and Technology. The paper proposes a formulation of different effective student learning outcomes selected from three different domains such as knowledge, skills, and values. The student learning outcomes were reformulated and distributed carefully to different methods of course evaluation based on specified teaching strategies. The contribution of each outcome through the whole course is calculated and distributed cumulatively to each teaching strategy used. This calculated weight is used to support the direct assessment method of course evaluation criteria by indicating the percentage of actual student achievement in each specified learning outcome concerning target and benchmark values. The effectiveness of the proposed method is verified by numerical examples.
Overcoming Barriers to Voter Mobilization during the COVID-19 Pandemic: A Case Study of St. Louis, Missouri
Authors: Parker Gary 
Published: September 2022

Abstract
Voters in St. Louis, Missouri, faced unprecedented challenges amid two critical elections during the 2020 election season. Voters were to determine if the state should expand access to Medicaid as well as decide the next President of the United States. The emergence COVID-19 complicated voter mobilization efforts as public health restrictions were implemented limiting access to voters. Additionally, the state quickly introduced new policies and rules that created confusion among voters. This study presents an in-depth qualitative case study of voter mobilization efforts in St. Louis by drawing on semi-structured interviews with 28 participants who engaged in voter mobilization within poverty-impacted communities in St. Louis City and St. Louis County. Subjects identified how they shifted tactics to allow for the health and safety of mobilizers and potential voters. Findings from this study provide evidence on how decision-making within the context of mobilization changes during wide scale social and political shocks.
A retrospective analysis of fetal heart defects in China: Investigating the influencing factors of pregnancy outcomes and evaluating the value of the multidisciplinary team cooperation approach
Authors: Li Shuang , Zhe Liu 
Published: September 2022

Abstract
Purpose To explore the impactors of pregnancy outcomes of fetal heart defects and evaluate the influence of a multidisciplinary team cooperation approach.
Methods A retrospective study of fetal cardiac defects diagnosed at our institution from January 2012 to June 2021 was carried out. Clinical data, including types of cardiac malformations, accompanying defects, genetic results, and pregnancy outcomes were analyzed.
Results Among 400 fetuses, 122 belonged to group A (single heart defect without extracardiac defect), 115 in group B (single heart defect with extracardiac abnormalities), 100 in group C (multiple cardiac defects without extracardiac abnormalities), and 63 belonged to group D (multiple cardiac defects with extracardiac abnormalities). The termination rate in the four groups was 44.26%, 86.09%, 70%, and 82.54%, respectively (P<0.05). Multiple logistics regression analysis revealed that co-existence of extracardiac defects (OR 7.347, CI 3.674,14.694), with pathogenic genetic anomalies (OR 7.493, CI 2.051,27.372), higher prognosis grades (OR 6.307, CI 3.943,10.088) and diagnosed in later gestational age (OR 0.819, CI 0.753, 0.890)were significantly associated with the termination of pregnancy. The MDT group had a significantly lower rate of pregnancy termination, particularly in groups C and D (p<0.001).
Conclusion It is important to process comprehensive cardiac and extracardiac ultrasound assessment and further genetic testing of fetal cardiac defects. Diagnosed gestational age, the severity of heart lesions, combined with extracardiac abnormalities, and identified pathogenic genetic abnormalities influence pregnancy outcomes. Multidisciplinary team cooperation is an effective approach and should be applied in fetal cardiac defects management to reduce unnecessary termination of pregnancy.
Toward a conceptual framework of health and its operational definition: an application in the 1958 British birth cohort
Authors: Joannès Camille , Collineaux Hélène , Guernec Gregory , Castagné Raphaële , Kelly-Irving Michelle 
Published: September 2022

Abstract
Background
Defining and measuring “Health” presents a challenge, partly due to its conceptual pluralism. To measure “Health” as an ability to adapt and self-manage, we developed an approach within the theoretical framework of resources and reserves over the life course, recently proposed in the literature. We aimed to (i) use the conceptual framework developed to identify indicators of deteriorating health reserves, (ii) construct a global health score from these indicators, (iii) evaluate the association between the global health score and subsequent health outcomes and (iv) assess the robustness of our method.
Methods
We used data from 7,043 individuals born in 1958 in Great Britain included in the National Child Development Study. A global health score was constructed via the sum of three selected indicators of deteriorating health reserves in mid-life: chronic widespread pain (CWP), clinical interview schedule (CIS-r), and allostatic load (AL). A three-category variable was defined: impaired/medium/optimal health. We explored criterion validity by modelling the relationships between the global health score, or each reserve taken separately, and mortality and self-rated health using Cox and logistic regressions respectively. We performed sensitivity analyses to assess the robustness of the method.
Results
Having an impaired global health score was significantly associated with all-cause premature mortality (HRimpaired= 2.74 [1.86; 4.05]) and an increased risk of later fair/poor/very poor self-rated health (ORimpaired = 7.50 [6.29; 8.95]). The global health score had a greater effect on the self-rated health estimates than each indicator of deteriorating health reserves considered separately (ORAL medium=1.82 [1.59; 2.09]; ORAL high=2.74 [2.37; 3.16]; ORCIS-r= 5.20 [4.45; 6.08]; ORCWP= 2.85 [2.53; 3.21]). Clinical interview schedule and allostatic load were also associated with premature mortality contrary to chronic widespread pain (HRAL medium1.82 [1.27; 2.61]; HRAL high= 3.10 [2.19; 4.40]; HRCIS-r=1.77 [1.22; 2.56]; HRCWP=1.32 [0.98; 1.76]). The multiple sensitivity analyses conducted allowed us to confirm the robustness of our method.
Conclusions
We proposed a method for measuring a global health score in line with a definition of health based on the concept of reserve. This method may be applied and further developed within the field of social and positive epidemiology.