bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pressure-Temperature-Fluid Constraints for the Formation of the Halo-Shakiso Emerald Deposit, Southern Ethiopia: Fluid Inclusion and Stable Isotope Studies
Authors: Nicol Carol-Anne , Marshall Dan , Einfalt Hans Christoph , Thorkelson Derek 
Published: February 2022

ABSTRACT
The Halo-Shakiso emeralds were discovered near the town of Shakiso in southern Ethiopia in 2016. They are gem quality, Cr-dominant emeralds hosted within ultramafic rocks and associated with Cambrian pegmatite intrusions of the Adola Belt. Aqueous-carbonic primary fluid inclusions hosted within emerald have a composition of approximately 3.0 wt.% NaCl eq. and an XCO2 of 0.06, with minor amounts of N2, CH4, and H2S. Stable isotope thermometry of contemporaneous quartz and emerald yields temperatures in the range of 420 to 470 °C. Combined stable isotope and fluid inclusion data are consistent with emerald precipitation at pressures ranging from 2.0 to 3.0 kbar, corresponding to depths of 5.9 to 8.9 km. Additionally, emerald channel water δD and calculated δ18O isotope values are consistent with an igneous origin for the fluids responsible for emerald precipitation; these fluids are also responsible for the metasomatization of the host rocks in and near the pegmatite, forming the phlogopite schist that is host to the Halo-Shakiso emeralds. The isotopic signatures, combined with the occurrence of adjacent pegmatites, support the classification of the Halo-Shakiso emerald deposit as a Tectonic-Magmatic-Related emerald deposit.
Thermal Instability–Induced Fundamental Magnetic Field Strands in the Solar Corona
Authors: Antolin Patrick , Martínez-Sykora Juan , Şahin Seray 
Published: February 2022

Abstract
Thermal instability is a fundamental process of astrophysical plasmas. It is expected to occur whenever the cooling is dominated by radiation and cannot be compensated for by heating. In this work, we conduct 2.5D radiation MHD simulations with the Bifrost code of an enhanced activity network in the solar atmosphere. Coronal loops are produced self-consistently, mainly through Joule heating, which is sufficiently stratified and symmetric to produce thermal nonequilibrium. During the cooling and driven by thermal instability, coronal rain is produced along the loops. Due to flux freezing, the catastrophic cooling process leading to a rain clump produces a local enhancement of the magnetic field, thereby generating a distinct magnetic strand within the loop up to a few Gauss stronger than the surrounding coronal field. These strands, which can be considered fundamental, are a few hundred kilometers in width, span most of the loop leg, and emit strongly in the UV and extreme UV (EUV), thereby establishing a link between the commonly seen rain strands in the visible spectrum with the observed EUV coronal strands at high resolution. The compression downstream leads to an increase in temperature that generates a plume-like structure, a strongly emitting spicule-like feature, and short-lived brightening in the UV during the rain impact, providing an explanation for similar phenomena seen with IRIS. Thermal instability and nonequilibrium can therefore be associated with localized and intermittent UV brightening in the transition region and chromosphere, as well as contribute to the characteristic filamentary morphology of the solar corona in the EUV.
Prevalence of Catheter-related Bloodstream Infection and Distribution of Multidrug Resistance Microorganisms among the Hospitalized Patients
Authors: Petri Oltiana , Vrenjo Klotilda , Angjeli Alda , Abazaj Erjona , Kika Blerta , Koraqi Andi , Daka Albana 
Published: February 2022

BACKGROUND: Central venous catheter (VC)-related bloodstream infection (CRBSI) is associated with high rates of morbidity and mortality in critically ill patients over the world.

AIM: The aims study is to evaluate the prevalence of CRBSI and to identify some of the factors.

METHODS: This was a retrospective, observational study carried out in the tertiary care hospital “Mother Theresa,” Tirana and American Hospital, Tirana, over a period of 3 years from January 2016 to December 2018. Data were collected retrospectively from various electronic sources shared by the hospitals and linked using patients’ unique medical record numbers. A total of 170 patients with indwelling VC were included in the study. The catheters were cultured using the standard procedure. Statistical analysis version SPSS-20 software was used for calculation of data.

RESULTS: Overall 170 patients analyzed in this study, the prevalence of CRBSI results 58.8%. The positivity from the University Hospital Center (UHC) “Mother Theresa” resulted 65.1% (82/126 cases) and the positivity from American Hospitals (AH) resulted 40.91% (18/44 cases). Patients from UHC Mother Theresa were (odds ratio) 2.69 times higher in risk for CRBSI compared to patients from AH, for confidence interval 95% (1.33–5.44) p value resulted to be with strong association = 0.005. The average age resulted 59.68 ± 14.26, with minimum age 9 years old and maximum age 83 years old. The most infected age groups resulted patients with age 61–70 years old. Central VC had a higher positivity compared to other catheters types. Regarding the spectrum of bacteria implicated in CRBSI infections, Gram positive bacteria (67%) were the most predominant compared to Gram-negative bacteria (33%), but regarding the antimicrobial resistance, the Gram-negative bacteria resulted majority of multidrug resistance.

CONCLUSION: The overall prevalence of CRBSI was 58.8%. Patients from Mother Theresa Hospital have the highest prevalence compared to patients of American Hospital. Men patients were the most predominant sex; age groups 61–70 years old presented the highest positive cases with CRBSI. Staphylococcus spp., Acinetobacter spp., Proteus spp., etc., were the most common isolate. We found antimicrobial resistance almost in all bacteria, but Gram-negative bacteria resulted majority of multidrug resistance.
The High Association of Ophthalmic Manifestations in Individuals With Mucolipidosis Type IV
Authors: Gibson David , Brar Vikram , Li Rachel , Kalra Arun , Goodwin Allison , Couser Natario 
Published: February 2022

Purpose:
To present a case report of mucolipidosis type IV (ML4) and review the literature for all of the ophthalmic abnormalities associated with this disease.

Methods:
A systematic review of the literature using PubMed/Medline was conducted, and with the addition of the current case report, the eye and ocular adnexa findings of 93 patients with ML4 are summarized.

Results:
The most common ophthalmic findings reported among the 93 patients included corneal clouding (90.3%), strabismus (58.1%), optic nerve pallor (52.2%), retinal dystrophy/pigmentary changes (50.5%), and retinal vascular attenuation (38.9%). Other less commonly reported findings included nystagmus, photophobia, ocular pain, excessive lacrimation, ptosis, and cataracts.

Conclusions:
The ophthalmic findings discussed in the current case report and literature review serve as indicators for ML4. Early diagnosis of ML4 is important in forming a multidisciplinary management plan, genetic counseling strategy, and maximizing the visual development of affected individuals.

[
J Pediatr Ophthalmol Strabimus
. 2022;59(5):332–337.]
Incidence and Risk Factors for Retinopathy of Prematurity in a Portuguese Cohort
Authors: Almeida Ana C. , Brízido Margarida , Teixeira Susana , Coelho Constança , Borrego Luís Miguel , Correia Miguel 
Published: February 2022

Purpose:
To evaluate the incidence and risk factors for retinopathy of prematurity (ROP) in two Portuguese neonatal units with a sub-analysis of infants with a gestational age (GA) of 28 weeks or older.

Methods:
This was a retrospective case series of all infants who underwent ROP screening from 2012 to 2020. Demographic, clinical, and laboratory data were collected. Univariate logistic regression was used to examine the risk factors for ROP followed by multivariate regression.

Results:

A total of 475 infants were included with a median GA of 30 weeks (range: 23 to 36 weeks) and a median birth weight of 1,229 grams (range: 408 to 2,620 grams). ROP was diagnosed in 113 infants (23.8%) and 29 (6.1%) were treated. In the multivariate analysis, GA and hyperglycemia were significantly associated with severe ROP (
P
< .001). In the subgroup analysis of infants with a GA of 28 weeks or older, bronchopulmonary dysplasia, late-onset sepsis, and hyperglycemia were linked to severe ROP.

Conclusions:
The incidence of ROP in the cohort falls within the range of other high-income countries. Hyperglycemia overpowered all of the other risk factors. Although rare, more mature infants are also at risk for severe ROP. Infants with older GA share the same group of risk factors, but bronchopulmonary dysplasia seems to play a greater role.

[
J Pediatr Ophthalmol Strabismus
. 2022;59(4):254–260.]
Characteristics and Outcomes of Idiopathic and Non-idiopathic Ocular Motor Apraxia in Children
Authors: Chang Melinda Y. , Grosrenaud Paul , Borchert Mark S. 
Published: February 2022

Purpose:
To systematically compare idiopathic and non-idiopathic ocular motor apraxia (OMA) in children.

Methods:
A retrospective chart review was conducted of all children (< 18 years) diagnosed as having OMA from 2010 to 2020. Demographics, clinical characteristics, and oculomotor outcomes were compared for children with idiopathic and non-idiopathic OMA.

Results:

Thirty-seven children were included, 17 (46%) with idiopathic OMA and 20 (54%) with non-idiopathic OMA. Among patients with non-idiopathic OMA, Joubert syndrome was the most frequent underlying diagnosis (30%). Strabismus (45% vs 12%,
P
= .04), nystagmus (30% vs 0%,
P
= .02), and vertical saccade involvement (25% vs 0%,
P
= .049) were significantly more common in non-idiopathic than idiopathic OMA, respectively. Neuroimaging abnormalities (90% vs 18%,
P
< .0001) and developmental delays (100% vs 59%,
P
= .002) were also more frequent in non-idiopathic than idiopathic OMA, respectively. Endocrine disorders (most commonly growth hormone deficiency) were diagnosed in 12% and 20% of children with idiopathic and non-idiopathic OMA, respectively (
P
= .67). On survival curve analysis, improvement in OMA occurred faster and more frequently in children with idiopathic than non-idiopathic OMA (median time to improvement 56 vs 139 months, respectively,
P
= .034).

Conclusions:
Non-idiopathic OMA is associated with a higher rate of vertical saccade involvement, nystagmus, and developmental delays. These findings should prompt neuroimaging in children with OMA. Additionally, endocrine disorders may be more frequent in children with OMA than the general pediatric population.

[
J Pediatr Ophthalmol Strabismus
. 2022;59(5):326–331.]
Clinical and Genetic Profile of Leber's Hereditary Optic Neuropathy in a Cohort of Patients From a Tertiary Eye Care Center
Authors: Bhate Manjushree , Kulkarni Sampada , Nalawade Rohan , Pujar Akhilesh 
Published: February 2022

Purpose:
To identify and describe the clinical profile at presentation in patients diagnosed as having Leber's hereditary optic neuropathy with primary and secondary mutations and correlate with treatment.

Methods:
A review of electronic medical records from January 2016 to December 2020 for proven cases of Leber's hereditary optic neuropathy was conducted. A total of 157 patients with clinically suspected Leber's hereditary optic neuropathy (143 males and 14 females) underwent genetic testing and 55 were found to have a mutation for Leber's hereditary optic neuropathy. Data of 55 consecutive patients were retrieved and analyzed for their clinical profile, investigations, mutations identified, treatment, and outcome.

Results:
All 55 patients were male, and the mean age was 23.80 ± 9.90 years (range: 9 to 53 years). The median duration of symptoms before the first physician examination was 6 months. The mean duration between the first hospital visit and genetically proven diagnosis of Leber's hereditary optic neuropathy was 9.03 ± 19.61 months (median: 2 months). More than half of the patients (n = 32; 58.2%) presented with severe to profound vision impairment in the better eye and 72.7% (n = 40) in the worse eye. Bilateral temporal disc pallor was more frequent in 38.2% (n = 21) and 36.4% (n = 20) had bilateral optic atrophy. Primary single mutations were detected in 61.81% (n = 34) and secondary mutations were detected in 38.2% (n = 21). The most common mutation was G11778A. One novel secondary mutation (A13615C) was identified in the cohort. Idebenone was used for treatment in 15 patients, and half of them (n = 8) showed an improvement in vision at 2 to 7 months of follow-up.

Conclusions:
The current cohort is the largest study to date in an Indian population that has analyzed the clinical presentations and mutations of Leber's hereditary optic neuropathy. G11778A was the most common primary mutation and several secondary mutations were identified. A delay in referral, inadequate compliance, and cost of care contributed to the outcomes.

[
J Pediatr Ophthalmol Strabismus
. 2022;59(5):344–349.]
Excellent Rectal Temperature Cooling Rates in the Polar Life Pod Consistent With Stationary Tubs
Authors: Miller Kevin C. , Amaria Noshir Yazdi 
Published: February 2022

Context
Several tools exist to reduce rectal temperature (TREC) quickly for patients experiencing exertional heatstroke (EHS). Stationary tubs effectively treat EHS but are bulky and impractical in some situations. More portable cold-water immersion techniques, such as tarp-assisted cooling with oscillation, are gaining popularity because of their benefits (eg, less water needed, portability). The Polar Life Pod (PLP) may be another portable way to reduce TREC, but few researchers have examined its effectiveness.

Objectives
To determine whether the PLP and stationary tub reduced TREC at acceptable or ideal rates, whether TREC cooling rates differed by method, and how participants felt before, during, and after cooling.

Design
Randomized crossover study.

Setting
Laboratory.

Patients or Other Participants
Thirteen individuals (8 men, 5 women; age = 21 ± 2 years, mass = 73.99 ± 11.24 kg, height = 176.2 ± 11.1 cm).

Intervention(s)
Participants exercised in the heat until TREC was 39.5°C. They immersed themselves in either the PLP (202.7 ± 23.8 L, 3.2 ± 0.6°C) or a stationary tub (567.8 ± 7.6 L, 15.0 ± 0.1°C) until TREC was 38°C. Thermal sensation and environmental symptom questionnaire (ESQ) responses were recorded before, during, and after exercise and cooling.

Main Outcome Measure(s)
Rectal temperature cooling rates, thermal sensation, and ESQ responses.

Results
Participants had similar exercise durations (PLP = 41.6 ± 6.9 minutes, tub = 42.2 ± 9.3 minutes, t12 = 0.5, P = .31), thermal sensation scores (PLP = 7.0 ± 0.5, tub = 7.0 ± 0.5, P &gt; .05), and ESQ scores (PLP = 25 ± 13, tub = 29 ± 14, P &gt; .05) immediately postexercise each day. Although TREC cooling rates were excellent in both conditions, the PLP cooled faster than the stationary tub (PLP = 0.28 ± 0.09°C/min, tub = 0.20 ± 0.09°C/min, t12 = 2.5, P = .01). Thermal sensation in the PLP condition was lower than that in the tub condition halfway through cooling (PLP = 1 ± 1, tub = 2 ± 1, P &lt; .05) and postcooling (PLP = 2 ± 1, tub = 3 ± 1, P &lt; .05). The ESQ scores were higher for PLP than for the stationary tub postcooling (PLP = 25 ± 14, tub = 12 ± 9, P &lt; .05).

Conclusions
The PLP and the stationary tub cooled individuals with hyperthermia at ideal rates for treating patients with EHS (ie, &gt;0.16°C/min). The PLP may be an effective tool for treating EHS when limited water volumes and portability are concerns. Clinicians should have rewarming tools and strategies (eg, heating blankets) available to improve patients' comfort after PLP use.
Study to compare Correlation between Digital Hemoglobin Meter and Hematology Analyzer in Hemoglobin Measurement
Authors: Dr. Jhalak Patel;  , Dr. Vishwas Amin  
Published: February 2022

Description of the Device Dolphin Digital Hemoglobin Meter
Haemoglobin measurement is widely performed in Blood bank [1] and screening, as Anemia is major health concern in India [2]. Different methods use for haemoglobin estimation like copper sulphate gravimetric method, Hemoglobin colour scale, HICN method, Automated Hematology analyzer, point of care haemoglobin meter etc
El video como herramienta TIC en inglés aplicada en el medio superior de la Universidad Autónoma de Campeche
Authors: González Mayté Cadena , Bojórquez María Alejandra Sarmiento , Rosado Juan Fernando Casanova 
Published: February 2022

El avance tecnológico hoy en día está inmerso en todo, incluyendo la educación, la cual debe seguir incorporando todas las TIC en sus estrategias de aprendizaje. Un recurso muy utilizado por los jóvenes para comunicarse en todo es el video, siendo este un excelente medio para aprender un nuevo idioma; en el nivel medio superior la unidad de aprendizaje de inglés en todos sus semestres evalúa la comprensión oral y escrita, es una herramienta perfecta para evaluar.
El objetivo del estudio es determinar si el alumno considera el elaborar videos como herramienta TIC como medio de enseñanza del idioma inglés en el nivel medio superior de la Universidad Autónoma de Campeche.
Un cuestionario autoadministrable fue aplicado a 86 sujetos. De estos hay un promedio de edad x= 17.06 y una DS = .725, Sobre si consideran la elaboración del video como herramienta útil, el 48.8% (42 sujetos) manifestaron estar de acuerdo, el 31.4% (27 sujetos) dicen estar totalmente de acuerdo, solo el 4.7% (4 sujetos) estuvieron en desacuerdo. También consideran que elaborar videos ayuda para el aprendizaje del idioma inglés, 45 sujetos (52.3%) manifestaron estar de acuerdo; 26 sujetos (30.2%) dijeron estar totalmente de acuerdo, solo 4 sujetos (4.7%) manifestaron estar en desacuerdo.
En conclusión, los estudiantes están de acuerdo que, al realizar videos en inglés utilizamos las TIC y estas ayudan a aprender el idioma, manifiestan que es una herramienta útil y una tecnología de información interactiva, permitiendo procesos de aprendizaje autónomos que consolidan los principios de “aprender a aprender”.
Adopsi Inovasi Layanan Online di Dinas Kependudukan dan Pencatatan Sipil Kota Samarinda
Authors: Rohmah Ainun , Abiyyu Khansa Yumna , Elisa Cindy , Nurasimah  , Pasapan Natalia Lembang , Safika  , Firdaus Muhammad Nur , Permatasari Noviani Reksa 
Published: February 2022

Konsep Smart City hadir sebagai upaya pemanfaatan teknologi untuk mengoptimalkan pelayanan kepada masyarakat. Salah satu bentuknya yaitu berupa pelayanan online untuk berbagai urusan masyarakat oleh institusi pemerintah. Penelitian ini dilakukan untuk mengetahui bagaimana proses adopsi inovasi pelayanan online via WhatsApp yang dilakukan Dinasi Kependudukan dan Pencatatan Sipil (Disdukcapil) Kota Samarinda dengan menggunakan Teori Difusi Inovasi. Penelitian ini menggunakan pendekatan kualitatif deskriptif. Data diambil dengan teknik penelitian lapangan, meliputi observasi dan wawancara mendalam dengan teknik purposive sampling untuk menetapkan informan. Hasil dari penelitian ini adalah pelayanan online via WhatsApp Disdukcapil berhasil diadopsi dari tahap pengetahuan hingga tahap konfirmasi, karena dianggap sesuai kebutuhan dan lebih fleksibel oleh informan. Pamflet dan banner menjadi saluran komunikasi yang berperan sebagai alat penyebarluasan informasi awal. Diketahui pula komunikasi interpersonal antara masyarakat dan perwakilan pemerintah berperan sebagai proses pertukaran informasi bagi adopter guna mendapatkan informasi tambahan. Kemampuan informan dalam menggunakan teknologi mempengaruhi persepsinya dalam melihat derajat keuntungan relatif, kesesuaian, dan kerumitan dari inovasi.
Potential use of Sesame (Sesamum indicum L.) oil and sesame oil cake in the development of spreadable cocoa cream
Authors: Guzmán Romel , Gómez Juieta , Chocrón Samuel 
Published: February 2022

Global trends in food in recent years indicate a marked interest of consumers towards certain foods, which, in addition to the nutritional value, provide benefits to the physiological functions of the human body. Sesame seeds (variety DV-9) was used for the formulation of cocoa-based spread products with partial addition of sesame oil and sesame oil cake. Physical characterization and chemical composition of raw materials and formulation were performed. The formulations presented rheological behaved like non-Newtonian fluids. F4 as thixotropic fluid and F2; F3; F5 as Bingham plastics. All formulations also presented superior nutritional properties compared to similar commercial products. The use of sesame seeds is beneficial and achievable
PROVENANCE EFFECT ON THE NUTRIENT COMPOSITION OF MORINGA OLEIFERA LEAVES
Authors: Azila J J , Okeke-Agulu K I , Mbah J J , Shoyemi-Obawanle A O , Olubunmi Shoyemi Aduratola 
Published: February 2022

Background: Moringa oleifera is a tree species to which a variety of benefits have been attributed and many of these benefits have through research been given scientific basis.
Purpose: The study aims to ascertain the effect of provenance on the nutrient composition of M. oleifera leaves.
Methods: The proximate composition of the M. oleifera leaves was determined using AOAC official method of analysis.
Results: The results of the analysis revealed the presence of high crude protein (26.43%) in Lafia compared to those obtained from Jos and Alkaleri. The results showed that M. oleifera leaves obtained from Jos has significantly higher (P>0.05) amount of ash, crude fiber, moisture content and lower fat content (P<0.05).Moringa leaves obtained from Lafia had a significantly higher amount of crude protein compared to the other locations assessed. Although M. oleifera leaves obtained from Alkaleri had a significantly higher (P<0.05) amount of nitrogen free extract compared to the other locations assessed.
Conclusion: The results showed that provenance have an effect on the nutrient composition of M. oleifera leaves and therefore, further studies need to be done to determine the effect of provenance sources other than those evaluated on the nutrient composition of M.oleifera leaves.
KONSEP DAN DESAIN ROAD TRIP VIRTUAL BERBANTUAN VIDEO KOTA PEKALONGAN BERBASIS WEB
Authors: Saut HS Dicke Junryan , Ismanto Bambang , Amalia Nurul 
Published: February 2022

Pandemi Covid-19 membawa dampak terhadap kegiatan wisata, sosial dan budaya. Kebijakan Pemerintah yang memberlakukan pembatasan kegiatan masyarakat menyebabkan masyarakat banyak bergiatan di rumah. Bahkan untuk pulang kampung dihari besar keagamaan juga dihimbau untuk tidak dilakukan. Kegiatan yang cukup signifikan terjadi peningkatannya adalah penggunaan internet, hal ini dibuktikan dengan adanya peningkatan pembelian pulsa dan paket data di masa Pandemi. Permasalahan di atas yang menjadi trigger disusunnya Konsep dan Desain Road Trip Virtual berbantuan Video Kota Pekalongan Berbasis Web. Road Trip Virtual Berbantuan Video Kota Pekalongan berbasis Web ini akan membawa pengunjung untuk menikmati jalan-jalan protokol dan beberapa lokasi wisata di kota Pekalongan dengan seolah-olah sedang menggunakan mobil (driving tour) berkeliling di jalan-jalan protokol di Kota Pekalongan atau sedang berjalan kaki (walking tour) berkeliling di lokasi-lokasi wisata di Kota Pekalongan. Disamping itu Web Road Trip Virtual dapat digunakan untuk mempromosikan kembali Kota Pekalongan kepada masyarakat sebagai kota destinasi wisata, juga untuk menarik turis baik yang sudah pernah berkunjung ke Pekalongan, maupun yang belum pernah. Konsep dan desainnya menggunakan metode pengembangan Multimedia dan tahapan pembuatan videonya mengacu pada 3 tahapan pembuatan video yakni praproduksi, produksi dan pascaproduksi.Â Kata KunciÂ Â Â :Â Â Â Â Â Â Â Â Â Â Konsep dan Desain, Road Trip Virtual, Kota Pekalongan, Video, Web, Pandemi Covid 19