bluuebunny/crossref_metadata_2025_split huggingface dataset:
A scoping review of methods to measure and evaluate citizen engagement in health research
Authors: Shahid Anmol , Lalani Inara N. , Rosgen Brianna K. , Sept Bonnie G. , Longmore Shelly , Parsons Leigh Jeanna , Stelfox Henry T. , Fiest Kirsten M. 
Published: December 2022

Abstract
Background
Citizen engagement, or partnering with interested members of the public in health research, is becoming more common. While ongoing assessment of citizen engagement practices is considered important to its success, there is little clarity around aspects of citizen engagement that are important to assess (i.e., what to look for) and methods to assess (i.e., how to measure and/ or evaluate) citizen engagement in health research.

Methods
In this scoping review, we included peer-reviewed literature that focused primarily on method(s) to measure and/or evaluate citizen engagement in health research. Independently and in duplicate, we completed title and abstract screening and full-text screening and extracted data including document characteristics, citizen engagement definitions and goals, and methods to measure or evaluate citizen engagement (including characteristics of these methods).

Results
Our search yielded 16,762 records of which 33 records (31 peer-reviewed articles, one government report, one conference proceeding) met our inclusion criteria. Studies discussed engaging citizens (i.e., patients [n = 16], members of the public [n = 7], service users/consumers [n = 4], individuals from specific disease groups [n = 3]) in research processes. Reported methods of citizen engagement measurement and evaluation included frameworks, discussion-based methods (i.e., focus groups, interviews), survey-based methods (e.g., audits, questionnaires), and other methods (e.g., observation, prioritization tasks). Methods to measure and evaluate citizen engagement commonly focused on collecting perceptions of citizens and researchers on aspects of citizen engagement including empowerment, impact, respect, support, and value.

Discussion and conclusion
We found that methods to measure and/or evaluate citizen engagement in health research vary widely but share some similarities in aspect of citizen engagement considered important to measure or evaluate. These aspects could be used to devise a more standardized, modifiable, and widely applicable framework for measuring and evaluating citizen engagement in research.

Patient or public contribution
Two citizen team members were involved as equal partners in study design and interpretation of its findings.

Systematic review registration

Open Science Framework (10.17605/OSF.IO/HZCBR).
Efficacy of native strains of entomopathogenic nematode, Heterorhabditis indica against the fall armyworm, Spodoptera frugiperda (J. E. Smith) (Lepidoptera: Noctuidae) from India
Authors: Shinde Swati P. , Ingole D. B. , Biradar V. K. , Gokte-Narkhedkar Nandini , Lavhe N. V. , Thube Shivaji H. , Shah Vivek , Prasad Y. G. 
Published: December 2022

Abstract
Background
The fall armyworm, Spodoptera frugiperda (J. E. Smith) (Lepidoptera: Noctuidae), is a notorious polyphagous pest that has recently invaded India in 2018. Within a short period, this pest has spread throughout the country, causing a significant damage to maize. In order to manage this menace, farmers rely on chemical insecticides, but due to concealed feeding nature of this pest insecticides remain ineffective in reaching the target site. In this context, the present study aimed to isolate, characterize and evaluate the reproductive potential of the native strains of entomopathogenic nematode, Heterorhabditis indica against larval instars of S. frugiperda under laboratory conditions.

Results
Two strains of H. indica isolated and characterized from the rhizosphere of mango and curry leaf trees were designated as CICR-HI-MN and CICR-HI-CL, respectively. Both strains, CICR-HI-CL and CICR-HI-MN showed differential mortality against 3rd (LC50 value of 21.65, 48.91 IJs/larva), 4th (LC50 value of 25.46, 52.36 IJs/larva) and 5th (LC50 value of 59.20, 71.04 IJs/larva) instar larvae of S. frugiperda, respectively. The instar-wise mortality of S. frugiperda showed that 3rd instar was relatively more susceptible compared to 4th and 5th instar larvae. In terms of efficacy, CICR-HI-CL was almost twice effective than CICR-HI-MN when LC50 and LC95 values of 3rd instar larvae were compared. However, the reproductive potential of both the strains was significantly higher against 5th instar than the 3rd and 4th instar larvae. Strain CICR-HI-CL was more effective in larval mortality, while nematode reproduction was higher in CICR-HI-MN.

Conclusions
Native strains of H. indica evaluated in the present study were found effective against larval instars of fall armyworm, S. frugiperda. Higher reproduction on 5th instar larvae demonstrates the ability of these strains to multiply, sustain and perpetuate on late instars of this polyphagous pest and may serve as viable option in integrated pest management program.
Efficacy of the entomopathogenic fungi Beauveria bassiana and Lecanicillium muscarium in the control of the tomato leaf miner, Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae)
Authors: Chouikhi Sabrine , Assadi Besma Hamrouni , Lebdi KaoutharGrissa , Belkadhi Mohamed Sadok 
Published: December 2022

Abstract
Background
Among the phytosanitary problems, affecting tomato crops in greenhouses heated by geothermal water in southern Tunisia, the tomato leaf miner, Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae) is gaining prominence from year to year.

Results
This study determined the susceptibility of eggs, second-instar larvae of T. absoluta to commercial formulations of the entomopathogenic fungi (EPF) Beauveria bassiana and Lecanicillium muscarium at different doses (1010, 109, 108, 107 and 106 spores/ml). Pathogenicity tests were carried out under controlled laboratory conditions at 27 ± 1 °C, and RH of 75 ± 5%, showed that the three commercial formulations of B. bassiana R444 (Bb-Protec®), B. bassiana ATCC 74,040 (Naturalis®) and L. muscarium Ve6 (Mycotal®) were effective against eggs and second instar larvae of T. absoluta. Mortality rates of eggs and larvae were high with increasing the concentrations of the fungi. B. bassiana ATCC 74,040 was the most effective one, with an egg mortality rate of (71.42%) and larval mortality was greater than (80%), at the highest concentration of 1010 spores/ml. The lethal concentration required to kill 50% of eggs was 1.56 × 108, 1.73 × 109 and 1.09 × 1010 conidia/ml for B. bassiana ATCC, B. bassiana R444, and L. muscarium, respectively. After 7 days, the median lethal concentration (LC50) values against larvae were the lowest for B. bassiana ATCC with 2.63 × 107 and 4.76 × 106 conidia/ml by way 1 and way 2 treatments, respectively. Thus, these three formulations affected the emergence of pest’s adults. The fungi significantly reduced pupation and adult emergence. Only 50.25, 60.15 and 69.16% of T. absoluta adults emerged in the treatments with B. bassiana ATCC, B. bassiana R444, and L. muscarium, respectively.

Conclusions
Biological performances of the EPF showed the role of a biological control agent that can be played against T. absoluta within the framework of an Integrated Pest Management program.
A Computed Tomography-based Radiomics Nomogram for Predicting Osteoporotic Vertebral Fractures: A Longitudinal Study
Authors: Wang Miaomiao , Chen Xin , Cui Wenjing , Wang Xinru , Hu Nandong , Tang Hongye , Zhang Chao , Shen Jirong , Xie Chao , Chen Xiao 
Published: December 2022

Abstract

Context
Fractures are a serious consequence of osteoporosis in older adults. However, few longitudinal studies have shown the role of computed tomography (CT)-based radiomics in predicting osteoporotic fractures.

Objective
We evaluated the performance of a CT radiomics-based model for osteoporotic vertebral fractures (OVFs) in a longitudinal study.

Methods
A total of 7906 individuals without OVF older than 50 years, and who underwent CT scans between 2016 and 2019 were enrolled and followed up until 2021. Seventy-two cases of new OVF were identified. A total of 144 people without OVF during follow-up were selected as controls. Radiomics features were extracted from baseline CT images. CT values of trabecular bone, and area and density of erector spinae were determined. Cox regression analysis was used to identify the independent associated factors. The predictive performance of the nomogram was assessed using the receiver operating characteristic curve, calibration curve, and decision curve.

Results
CT value of vertebra (adjusted hazard ratio (aHR) = 2.04; 95% CI, 1.07-3.89), radiomics score (aHR = 6.56; 95% CI, 3.47-12.38), and area of erector spinae (aHR = 1.68; 95% CI, 1.02-2.78) were independently associated with OVF. Radscore was associated with severe OVF (aHR = 6.00; 95% CI, 2.78-12.93). The nomogram showed good discrimination with a C-index of 0.82 (95% CI, 0.77-0.87). The area under the curve of nomogram and radscore were both higher than osteoporosis + muscle area for 3-year and 4-year risk of fractures (P &lt; .05). The decision curve also demonstrated that the radiomics nomogram was useful.

Conclusion
Bone radiomics is associated with OVF, and the nomogram based on radiomics signature and muscle provides a tool for the prediction of OVF.
Extensive Peritonectomy is an Independent Risk Factor for Cisplatin HIPEC-Induced Acute Kidney Injury
Authors: Liesenfeld Lukas F. , Quiring Eva , Al-Saeedi Mohammed , Nusshag Christian , Büchler Markus W. , Schneider Martin 
Published: December 2022

Abstract
Background
Cisplatin (CDDP)-containing hyperthermic intraperitoneal chemotherapy (HIPEC) is frequently applied in selected patients with peritoneal malignancies derived from ovarian cancer, gastric cancer, and primary peritoneal mesothelioma. HIPEC with CDDP increases perioperative morbidity, in particular by inducing acute kidney injury (AKI). Factors contributing to occurrence of AKI after intraperitoneal perfusion with CDDP have not been sufficiently evaluated.

Patients and Methods
Data from 63 patients treated with a CDDP-containing HIPEC regimen were retrospectively analyzed concerning demographics, underlying disease, surgery, and HIPEC details to evaluate risk factors of AKI. A preclinical rat perfusion model was applied to assess the influence of temperature, concentration, perfusate volume, perfusion flow rate, and extent of peritonectomy on drug absorption upon intraperitoneal CDDP perfusion.

Results
AKI occurred in 66.1% of patients undergoing CDDP-containing HIPEC, with total intraoperative fluid influx being a negative and the extent of parietal peritonectomy being a positive independent predictor of postoperative AKI. In a preclinical model, bilateral anterior parietal peritonectomy significantly increased systemic CDDP absorption by 1.6 to 2-fold. CDDP plasma levels in animals were significantly higher after both perfusion with increased CDDP perfusate concentrations and bilateral anterior parietal peritonectomy.

Conclusion
CDDP-containing HIPEC is associated with relevant morbidity owing to its systemic toxicity. Extent of parietal peritonectomy is an independent predictor of AKI. CDDP dose reduction should be considered in case of extensive parietal peritonectomy. Cytostatic drug concentrations in HIPEC perfusate should be paid more attention to than total dose per body surface area. Further clinical studies are needed to confirm the presented preclinical findings.
E-sport related intrinsic and extrinsic motivation in practice. Initial psychometric properties of the “E-sport and ME” questionnaire
Authors: Horoszkiewicz Krzysztof , Załęski Grzegorz , Horoszkiewicz Bartosz 
Published: December 2022

Background. The popularity of eSports is rapidly increasing, and PC gamers are watched by crowds of spectators similarly to traditional sports.
The aim. E-Sport and ME questionnaire was created to assess motivation for playing video games and competing in tournaments.
Material and methods. The theoretical background was grounded in self-determination theory (SDT).
The results of 203 men aged 14 to 33 years (M = 20.4; SD = 3.4) were studied. Exploratory and confirmatory factor analyses (EFA and CFA) were conducted.
Results. Both EFA and CFA indicated two solid factors: extrinsic and intrinsic motivation [Comparative Fit Index = 0.995, Tucker Lewis Index = 0.994, Root Mean Square Error of Approximation = 0.046 (CI 0.00 – 0.08), Standardized Root Mean Square Residual = 0.075 (χ2 = 64.16, df = 53)]. Both scales had a high level of internal consistency (> α = 0.8). Respondents from professional e-sports clubs have higher extrinsic motivation than amateurs; intrinsic motivation takes place on similar level.
Conclusions. The statistical analysis of e-sport and myself revealed a high level of internal consistency as well as the identification of two distinct factors. This could aid coaches and players in outlining the dominant type of motivation for playing video games. The shown version should be further explored and validated to increase its generalizability.
Exploring the effect of silver nanoparticles on gene expression in colon cancer cell line HCT116
Authors: Alobaid Hussah M. , Daghestani Maha H. , AL-Malahi Nawal M. , Alzahrani Sabah A. , Hassen Lina M. , Metwally Dina M. 
Published: December 2022

Abstract
This study describes a new green method for silver nanoparticles (AgNPs) using Cymbopogon proximus (CP) extract and evaluates their potential anticancer properties in HCT116 cells. Ultraviolet-visible spectroscopy, transmission electron microscopy, dynamic light scattering, and Fourier transform infrared (FTIR) spectroscopy were used to successfully analyze the AgNPs. FTIR spectral analysis revealed the presence of phytochemicals that could be responsible for silver (Ag) ion reduction and AgNP capping. The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay demonstrated that treating HCT116 cells with PC-AgNPs for 48 h caused cytotoxic effects, as evidenced by the existence of 20% cell viability. The RT-qPCR study revealed that the expression of two oncogenes (cathepsin B [CTSB] and epithelial cell adhesion molecule [EpCAM]) was significantly reduced in treated cells. The levels of various tumor suppressor genes, including adenomatous polyposis coli (APC), Beclin1 (BECN1), nuclear translocation of β-catenin (CTNNB1), low-density lipoprotein receptor-related protein 6, LRP5, TP53, and TNF, were dramatically reduced in cells treated with CP extract, but this was not the case in cells treated with CP extract. To conclude, CP-AgNPs have demonstrated their ability to induce cytotoxic action and exert antitumorigenic modulatory effects, particularly on the expression of CTSB and EpCAM in colon cancer cells, utilizing AgNPs as an antitumor therapeutic agent for 48 h is not recommended, and reducing the treatment time could be more effective.
English and Chinese existential constructions in contrast: A corpus-based semantic study
Authors: Chen Qiaoyun 
Published: December 2022

AbstractThis article contrasts existential constructions in English and Chinese in terms of semantic variability and dimensions of semantic variation, distribution of Definiteness Effect and existentiality on the basis of corpus instances and their contextual features. Exploratory and confirmatory analyses show that: (1) existential construction in English varies more widely than its Chinese counterpart; (2) existential constructions in English and Chinese differ in covert/overt expression of background information, semantics of the existential verb and the noun phrase (NP) whose existence is asserted as well as an interaction between presence of a coda and NP definiteness. Contextual features such as semantics, number, quantification and modifier of NP and covert/overt expression of background information are found to have a significant effect on the distribution of Definiteness Effect. The survey on existentiality indicates that the concept has multiple manifestations in form. Reasons for these linguistic phenomena are discussed from various perspectives.
Discourse function of personal pronouns in a slavic pro-drop language: Evidence from Croatian L1 argumentative writing
Authors: Cvikić Lidija , Ordulj Antonia 
Published: December 2022

Abstract
At the discourse level, personal pronouns have been acknowledged as one of the most important features used to express writer visibility – involvement of the author in the text. Studies have shown that writer visibility depends on discourse type, cultural conventions, writer’s L1, etc. (Petch-Tyson 1998; Ädel 2001; Rodríguez, Vázquez and Guzmán 2011; Zolotova 2014). This paper investigates the discourse function of personal pronouns in argumentative writing in the Croatian language, a Slavic pro-drop language. For the purpose of this paper argumentative essays written by Croatian native speakers (N=100) are analysed for the frequencies of 1st and 2nd person personal pronouns and their discourse functions.
The results confirmed low frequency of 1st and 2nd person personal pronouns in the corpus, with the dominance of the 1st person singular personal pronoun I. The qualitative analysis shows that the pronoun I is most frequently used to express discourse functions of writer’s stance and writer’s experience, whereas all of the other pronouns were used mostly to express more general claims. The obtained results gave more insight into the use of personal pronouns in a pro-drop language and confirm cultural and linguistic influences on argumentative writing in the first language.
The diachronic evolution of posture verbs in Chinese
Authors: Xiao Lin 
Published: December 2022

Abstract
The linguistic properties of the three most common verbs of posture, which express positions, such as zuò ‘sit’, zhàn ‘stand’, tǎng ‘lie’ have been thoroughly studied in a wide range of languages belonging to typologically different language families, but they have never been extensively investigated in Chinese. Our article traces the diachrony of these verbs from the Archaic Chinese period (5th - 2nd centuries BCE, corresponding to the Classical Chinese by excellence) to the present-day Chinese, showing that they have very rarely been grammaticalized into aspect markers, as has been the case in other languages. We also examine the semantic distinction between the expression of a dynamic vs. static action, as well as the syntactic behavior of these positional verbs. We finally discuss their links with locative / existential verbs from the Early Medieval Chinese onwards (3rd c. CE) and the grammaticalization path that has been hypothesized according to which the posture verbs have been first reanalyzed into locative/existential verbs before being grammaticalized into aspectual markers will be tested.
Fragment questions in Chinese: At the syntax-pragmatics interface
Authors: Yang Xiaolong , Zhou Yong 
Published: December 2022

AbstractFragment questions (henceforth FQs) in Mandarin Chinese usually end up with the particlene. In the literature (e.g. Wei 2013, 2016, 2018), Chineseneis construed as functioning similarly to Koeran particle-yoand Chinese FQs are analyzed as a fronting-ellipsis phenomenon. Within the framework of Dynamic Syntax (Kempson et al. 2001; Cann et al. 2005), a parsing-based account of Chinese FQs is proposed, showing that (i)nein Chinese FQs will trigger the REGENERATION process to re-use a macro of actions stored in the previous context; (ii) Semantically, Chinese FQs are often employed as queries about another relatively separate event in connection with the previous one; pragmatically, FQs shows speakers’ interest towards additional information.
Transcending and Calling – One Hundred Years of Philosophical Study in China and its Future Tendency
Authors: Li-wen Zhang 
Published: December 2022

Abstract
The central topic for the philosophical study in China during the past century was to relate our study to Western philosophy and solve the problem of the modernization of Chinese philosophy. Thus, the development of Chinese philosophy during this period is marked by identifying itself with Western criteria of values in addition to its self-orientation, self-introspection, self-development, and self-perfection. In the 21st century, Chinese philosophers will transcend the boundaries of the country to reconcile itself with the world and, at the same time, maintain a style of our own and set up a new theoretical system of Chinese philosophy.
At the turn of the century and millennium, it is customary to look back and summarize the state of development of this century, drawing inspiration and lessons from it to anticipate and look forward to the next century. Since the 1990s, Chinese philosophical circles have held various forms of seminars on this topic, raising insightful and contemplative questions that have contributed significantly to an in-depth exploration of the issue.
Entschärfung des Essentialismusvorwurfs: Einige methodische Überlegungen zur Praxis der Kulturphilosophie
Authors: Ames Roger T. 
Published: December 2022

ZusammenfassungEin wohlbekannter kritischer Einwand gegen jene unter uns, die versuchen, kulturelle Unterschiede im Dienste verantwortungsvoller kultureller Vergleiche hervorzuheben, richtet sich darauf, dass wir uns dabei der Essentialisierung genau dieser Kulturen schuldig machen. Essentialismus ist dabei als eine Verallgemeinerung zu verstehen, die besagt, dass bestimmte Eigenschaften einer gegebenen Bevölkerung innerhalb dieser Kultur universell und zugleich ihr eigentümlich sind, demnach nicht von kontingenten Kontexten abhängen und dass wiederum ebendiese Eigenschaften Relativismus und Inkommensurabilität unter den Kulturen bedingen. In diesem Essay möchte ich den Widerstand einiger zeitgenössischer Forscher anfechten, die es ablehnen, grobe kulturelle Verallgemeinerungen als notwendig zu akzeptieren, wenn es darum geht, die reichhaltigen Differenzen, die zwischen Traditionen walten, zu respektieren und so weit als möglich einen verarmenden Kulturreduktionismus zu vermeiden. Ich würde voraussetzen, dass die Wipfel eines kontinuierlich emergierenden kulturellen Vokabulars selbst in einem tiefen und relativ stabilen Grund aus unbenannten Annahmen wurzeln, die sich über Generationen in der Sprache, den Gebräuchen und den Lebensformen einer lebendigen Tradition abgelagert haben. Und weiter möchte ich argumentieren, dass das Versäumnis, den fundamentalen Charakter kultureller Differenzen als eine ursprüngliche Absicherung gegen die Vergehen des „Essentialismus“ anzuerkennen, selbst nicht harmlos ist. Tatsächlich bewirkt diese Ablehnung kultureller Verallgemeinerungen ironischerweise eine unkritische Essentialisierung der je eigenen kulturellen Annahmen, so dass sich ebendiese Voraussetzungen in die Interpretationen der Lebens- und Denkweisen anderer Traditionen einschleichen.
Literature and Philosophy in Global Dialogue: The Educational Encounter
Authors: Chamat Natalie 
Published: December 2022

Abstract

Literature-Philosophy apprehends the encounter of literature and philosophy as an open dialogue, where the commonality of a specific distance with regard to
ἐπιστήμη
serves to open up discourse beyond knowledge and epistemology. This article serves the purpose to argue for
reading in translation
as a core element of the methodological toolkit and part of a study-focus on Literature-Philosophy in a curriculum of Global Philosophy. It will therefore start by sketching a contextualization of
Tschuang-Tse. Reden und Gleichnisse
, Martin Buber’s poetic renderings of 莊子
,
to introduce into how and why his philosophy of dialogue in her educational form stays trapped within an aesthetically motivated hierarchy of explanation.
Le maître ignorant
by Jacques Rancière will provide a restructuring of the educational encounter as a kind of emancipatory literary poetics of subjectivation inquiry and experience that is political, rather than power-related.