bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimum Location of Shear Wall in G+6 Building at the Outer Periphery Using Pushover Analysis
Authors: M Saravanakumar R , S Samson 
Published: September 2022

Abstract
Many studies have been conducted in recent years to determine how well buildings handle lateral forces. However, the location of the shear wall when a building is subjected to lateral force was not thoroughly studied. It is well known that performance-based design is the best method for determining the ideal location. Pushover analysis is used to find the best location for this study. When conducting a pushover analysis, the relationship between base shear and roof displacement is typically depicted in the capacity curve. Various shear walls are placed throughout the building as part of this analysis to determine the exact location. The PushSW6 model had the highest shear carrying capacity out of 13 models tested, making it the best option for placement. When compared to the model without a shear wall, the shear carrying capacity of the PushSW6 model is 76.66% higher. From here, it is clear that PushSW6's shear walls will be the best location out of the 13 models.
Design of a new voice cryptosystem based on the global Mittag-Leffler synchronization of mismatched chaotic systems with unknown parameters, fractional orders, time delays and external disturbances
Authors: Razmara Susan , Yahyazadeh Meisam , Marj Hassan Fatehi 
Published: September 2022

Abstract
In this research, first two chaotic systems with unknown parameters, mismatched structures, different fractional derivative orders, non-identical time delays, and external disturbances are synchronized based on the Mittag-Leffler stability analysis. Then, using the synchronized systems, a new voice cryptosystem is designed to securely send voice messages via public communication channels. Finally, numerical simulations confirm that the designed voice cryptosystem possesses an easier practical implementation, more secure and accurate results, and a higher security level than previous voice cryptosystems.
The Impact of Neoadjuvant Systemic Treatment on Postoperative Complications in Breast Cancer Surgery
Authors: Maggi Nadia , Nussbaumer Rahel Lea , Castrezana Liliana , Zehnpfennig Lea , Schwab Fabienne D , Krol Janna , Oberhauser Ida , Weber Walter Paul , Kurzeder Christian , Haug Martin D , Kappos Elisabeth A 
Published: September 2022

Abstract
Purpose: The aim of the study was to analyse the impact of neoadjuvant systemic treatment (NST) on postoperative complications and the beginning of adjuvant treatment.
Methods: This study includes data from a prospectively maintained database including patients with breast cancer (BC) stage I-IV with or without NST undergoing breast cancer surgery between January 2010 and September 2021.
Results: Out of 517 enrolled patients, 77 received NST, 440 had primary breast surgery. After NST patients underwent surgery after a meantime of 34 days (26.5 – 40 days). No statistical significance could be found comparing the complication grading according to the Clavien Dindo classification. The complications were most frequently rated as grade 3b. There were no complications with grade 4 or higher. When differentiating into short and long-term, the overall rate of short-term complications was 20.3% with no significant difference between the two groups (20.8% vs. 20.2%). Regarding long-term complications, there was more impairment of shoulder mobility (26.0% vs. 9.5%, p = < 0.001) and chronic pain (42.9% vs. 28.6%, p = < 0.016) for patients with NST. The beginning of the administration of the adjuvant treatment was comparable in both groups (46.3 days vs. 50.5 days).
Conclusion: In our cohort, complications between both groups were comparable according to Clavien Dindo. This study shows that NST has no negative impact on postoperative short-term complications and most importantly did not lead to a delay of the beginning of adjuvant treatment. Therefore, NST can be safely admitted, even when followed by extensive breast reconstruction surgery.
Unraveling the linkages between dominant plants and pathogen antagonistic potential of soils in Antarctic terrestrial ecosystems
Authors: Naz Beenish , Liu Ziyang , Malard Lucie , song Hongxian , Xiao Sa , Ali izhar , Wang Yajun , Li Xin , Usman Muhammad , Ali Ikram , Gao Haining , Liu Kun , Lizhe An , Chen Shuyan 
Published: September 2022

Abstract
Aims
This study investigated the direct effects of Antarctic dominant plants and indirect effects via soil edaphic properties on bacterial antagonistic potential. The study evaluated the underlying mechanism of intricate interactions between plants, soil, and microbes that mutually shape bacterial antagonism in terrestrial Antarctica.
Method
Using soil from two different vegetation types (Grasses and Mosses) and bulk soil, we identified the potential of soil bacterial communities to combat plant pathogens in each of these soils using in vitro plate assays with indicator strains to demonstrate suppression. Specifically, we investigated the soil bacterial community composition and diversity contrasting dominant plants and determined bacterial antagonist density, frequency, and inhibition potential concerning plant pathogens. We present a pathway-oriented methodology that uses structural equation modeling (SEM) to demonstrate complex interactions between plants, soil, and microbes.
Results
The findings suggested that the abundance of Actinomyces, Bacillus, and Pseudomonas was significantly and positively influenced by mosses. Dominant plants modify the abiotic soil characteristics and bacterial community abundance, influencing the bacterial antagonistic potential. SEMs demonstrated that the presence of dominant plants significantly influenced antagonistic potential. However, the presence of grasses strongly impacted Actinomyces and Pseudomonas, while Bacillus remained unaffected. Our results emphasize the significance of soil functioning, such as the pathogen antagonistic potential of Antarctic soils, as being influenced by dominant plant composition.
Conclusions
We conclude that Antarctic dominant plants significantly impact soil bacterial communities and their antagonistic potential. Furthermore, soil associated with mosses is found more conducive to antagonistic bacterial communities than grasses in Antarctica.
The association between systemic inflammatory response index and new-onset atrial fibrillation in patients with ST-elevated myocardial infarction treated with percutaneous coronary intervention
Authors: Wang Jingfeng , Hu Sisi , Liang Cheng , Ling Yang 
Published: September 2022

Abstract
Background: New-onset atrial fibrillation (NOAF) complicating with ST-elevated myocardial infarction (STEMI) patients following percutaneous coronary intervention (PCI) is associated with worse prognosis. The systemic inflammatory response index (SIRI), serves as a novel inflammatory indicator, is found to be predictive of adverse outcomes. The aim of this study is to explore the association between NOAF and SIRI.
Methods: A retrospective data included 616 STEMI participants treated with PCI in our cardiology department had been analyzed in present investigation, of which being divided into a NOAF or sinus rhythm (SR) group based on the presence or absence of atrial fibrillation. The predictive role of SIRI for in detecting NOAF had been evaluated by the logistic regression analyses and receiver operating characteristic (ROC) curve. Additionally, long-term all-cause mortality between both groups was compared using the Kaplan-Meier test.
Results: NOAF during hospitalization developed in 7.6% of PCI-treated individuals. After multivariate regression analyses, SIRI remains to be an independently predictor of NOAF (odds ratio: 1.782, 95% confidence interval: 1.675-1.906, P = 0.001). In the ROC curve analysis, SIRI with a cut-off value of 4.86 was calculated to predict NOAF, with4.86, with a sensitivity of 80.85% and a specificity of 75.57%, respectively (area under the curve (AUC) = 0.826, P ＜ 0.001). Furthermore, pairwise compassion of ROC curves displayed the superiority of SIRI in the prediction of NOAF in comparison with that of neutrophil/lymphocyte or monocyte/lymphocyte (P ＜ 0.05). In addition, the participants in NOAF group had a significantly higher incidence of all-cause death compared to those in SR group after a median of 40-month follow-up (22.0% versus 5.8%, log-rank P ＜ 0.001).
Conclusion: SIRI can independently predict NOAF in patients with STEMI after PCI, with being positively correlated to worsened outcomes.
Stability assessment of human standing posture
Authors: Błaszczyk Janusz Wiesław , Beck Monika 
Published: September 2022

Abstract
The interaction of the neuromuscular mechanisms ensuring optimal stability of human standing posture is not fully clarified. To explain this problem in the present study, we focused on identifying a human posture control system based on the assessment of center-of-gravity (COG) trajectory characteristics during the erect posture. Towards this aim, a transdisciplinary multilevel grey-box model of standing posture control has been proposed and then verified experimentally. Trajectories of COG during quiet stance were assessed in a large group of young healthy subjects, known for the most stable posture. Additionally, the impact of visual input on the COG output was analyzed to assess the robustness of the control. We assumed that in physiological conditions human erect posture can be efficiently stabilized by the ankle joint muscles mainly. Respiratory and circulatory rhythms disturb the COG positioning which results in its random oscillations in the vicinity of the setpoint. Observed in young healthy individuals, the spatiotemporal characteristics of the COG oscillations support the notion that the human standing posture is maintained by a dedicated linear time-invariant control system.
Assessment of the Disassemblability of Electric Bicycle Motors for Remanufacturing
Authors: Erdmann Julian Grosse , Koller Jan , Brimaire Jil , Döpper Frank 
Published: September 2022

Abstract
In 2021, sales of electric bicycles in Germany increased compared to the previous year, leading to a 43% share of electric bicycles in the total bicycle market. The German Bicycle Industry Association (ZIV) expects this growth to continue and that by 2025 every second bicycle sold in Germany will have an electric motor. Therefore, due to the increasing popularity, both the built-in resources and the possible treatments after the use phase need to be considered regarding sustainable market development. In this context, remanufacturing is one promising end-of-life strategy that enables a new life cycle of products and components, thus reducing the consumption of natural resources and minimizing waste production. The used products are restored to their original conditions by disassembling, cleaning, sorting, reconditioning, and reassembling. Thereby, disassembly is a decisive process step as it creates the prerequisites for all further steps in the process chain and significantly determines the economic feasibility of a remanufacturing process. Therefore, this paper aims to evaluate the ease of disassembly of electric bicycle motors and thus determine their suitability for remanufacturing. To evaluate the disassemblability, the ease of Disassembly Metric (eDiM), a quantitative assessment method for evaluating disassembly effort, was adapted to the needs of the electric bicycle motors. The method was finally applied to five electric bicycle motors from established manufacturers and assessed their ease of disassembly. The results showed that the electric bicycle motors can be disassembled without significant damage and classified as suitable for remanufacturing based on their disassembling ability.
Influence of weight-bearing on the 3D movement of lumbar facet joints in sitting position
Authors: Han Ye , Wang Xiaodong , Wang Jianzhong , Sun Shaosong , Xia Xi , Wang Jing , Miao Jun 
Published: September 2022

Abstract
Background
Recognizing the motion characteristics of lumbar facet joints is helpful to prevent and treat lumbar degenerative diseases. At present, the research on the motion of lumbar facet joints is mainly focus on motion characteristics of lumbar facet joints without weight-bearing. However, there is no related research on whether weight-bearing has an effect on facet joints in sitting posture. The purpose of this study was to analyze the motion characteristics of lumbar facet joints and to observe the effect of weight-bearing on lumbar facet joints in sitting position.
Methods
Ten normal subjects (5 males and 5 females) were recruited and scanned by CT, and their lumbar 3D models were reconstructed by software. The images of flexion and extension of lumbar facet joints in sitting position were collected without weight-bearing and weight-bearing 10kg, and the 2D model was constructed by software. The 2D-3D model was matched to restore the flexion and extension motion changes of the subjects' lumbar spine in the sitting position, and the relevant data of facet joinets were collected.
Results
In the L3/4 segment, After weight loading, the displacement of the left facet joint in the X axis became larger, while that in the Y axis and Z axis became smaller. the displacement of the right facet joint in the X axis and Y axis became larger, and the Z axis displacement became smaller. The rotation angle of bilateral facet joints also became smaller. In the L4/5 segment, after loading, the displacement of the X、Y、Z axis displacement of both sides becomes larger, while the rotation angle of α and β increases, while the rotation angle of γ decreases. In the L5/S1 segment, the displacement of the X、Y、Z axis on the left side becomes smaller. The displacement of the X、Y axis on the right side becomes smaller, while the displacement on the Z axis becomes larger. The rotation angle of α and γ becomes larger, and the rotation angle of the β axis becomes smaller.
Conclusion
when sitting, the flexion and extension distance and rotational displacement of lumbar facet joints are not affected by weight-bearing. In addition, there is asymmetry in the movement of the left and right facet joints, and the weight-bearing has no effect on the asymmetry of the motion.
Providing patient-centered care for patients with multidrug- or rifampicin-resistant tuberculosis in Wuhan, China
Authors: Nie Qi , Sun Dan , Zhu Muxin , Tu Shengjin , Chen Nanshan , Chen Hua , Zhou Yong , Xiao Fan , Yao Ge , Chen Huidong , Zhang Tongcun , Yang Chengfeng , Tao Lixuan 
Published: September 2022

Abstract

Aim: This study was conducted to determine the impact of patient-centered care (PCC) on treatment adherence and outcome of patientswith multidrug- or rifampicin-resistant tuberculosis (MDR/RR-TB).
Background: Treatment adherence is critical to successful outcomes of MDR/RR-TB. However, very few studies published had addressed how to improve it.
Methods: This study retrospectivelyanalyzed treatment outcomes of MDR/RR-TB patient with two different kinds of care: clinical care for group A and PCC for group B.
Results: There were 128 patients were assigned in group A and 155 patients in group B. Patients in group B achieved a higher rate of negative 6-month sputum culture conversionthan those in group A (81.6% versus 95.3%, P = 0.0141). The treatment success rates of group A and B were 46.9% versus 68.4% (P = 0.0003), while failure, death, and default rates were4.7%, 9.4%, and 39.1% in group A, versus 1.3% (P = 0.1751), 12.9% (P = 0.3509), and 17.4% (P = 0.0000) in group B, respectively.
Conclusions: The PCC promoted MDR/RR-TB patients’ adherence and improved treatment outcomes.
Revised calculation of the coefficient of parentage in plant breeding
Authors: Hernandez-Suarez Carlos , Montesinos-López Osval 
Published: September 2022

Abstract
Background
The Coefficient of Parentage (COP) between two individuals is the expected inbreeding of their offspring. Originally exploited by animal breeders, is now a routine calculation among plant breeders as part of crop improvement programs.%if any
Results
To calculate the COP between two individuals, one selects an allele at random from the same loci of each individual and calculate the probability that they are identical by descent. Nevertheless, to calculate the COP between two strains, we first need to select an individual at random from each strain to perform the calculation. The sampling process adds some independence that simplifies the calculation in the case of strains. We use this fact to provide a simple methodology to calculate the correct coefficient of parentage between strains.
Conclusions
The COP between strains requires a different calculation than the used to calculate the COP between individuals. Failure to do so may result in an overestimation of the amount of inbreeding.
Unravelling the community of arbuscular mycorrhizal fungi associated with endemic plants from a neotropical dry forest
Authors: Silva Antonio Marcos Miranda , Feiler Henrique Petry , Lacerda-Júnior Gileno Vieira , Fernandes-Júnior Paulo Ivan , Aidar Saulo Tarso , Araújo Victor Araújo Vieira Prudêncio , Matteoli Filipe Pereira , Pereira Arthur Prudêncio Araújo , Melo Itamar Soares , Cardoso Elke Jurandy Bran Nogueira 
Published: September 2022

Abstract

Arbuscular mycorrhizal fungi form symbiotic associations with 80% of all known plants, allowing the fungi to acquire plant-synthesized carbon, and confer an increased capacity for nutrient uptake by plants, improving tolerance to abiotic and biotic stresses. We aimed to characterize the mycorrhizal community associated with Neoglaziovia variegata (so-called `caroa`) and Tripogonella spicata (so-called resurrection plant) using high-throughput sequencing of the partial 18S rRNA gene. Both endemic plants to neotropical dry forests and shrubland ecosystems were sampled in the Caatinga biome, located in northeastern Brazil. Illumina MiSeq sequencing of 37 rhizosphere samples (19 for N. variegata and 18 for T. spicata) revealed a distinct mycorrhizal community between the studied plants. There is a lack of information regarding the mycorrhizal composition of these plants, as revealed by our systematic review. According to alpha diversity analyses, T. spicata showed the highest richness and diversity based on the Observed ASVs and Shannon index, respectively. The four most abundant genera (higher than 10%) found were Glomus, Gigaspora, Acaulospora, and Rhizophagus, with Glomus being the most abundant in both plants. Nonetheless, Gigaspora, Diversispora, and Ambispora were specific for N. variegata, whilst Rhizophagus, Paraglomus, and Archaeospora were only associated with T. spicata. Therefore, the arbuscular mycorrhizal fungi community showed a genus-specific niche, and hence they may be differentially assisting the plants in the harsh environment of the Caatinga biome.
Anti-CTLA-4 antibody might be effective against non-small cell lung cancer with large tumors
Authors: Saijo Hiroshi , Hirohashi Yoshihiko , Honjo Osamu , Saikai Toyohiro , Shijubo Naoki , Takabatake Hirotsugu , Fujita Akihisa , Honda Yasuhito , Koba Hiroyuki , Chiba Hirofumi , Torigoe Toshihiko 
Published: September 2022

Abstract
Background
Immunotherapy using immune checkpoint inhibitors (ICIs) has revolutionized the treatment of advanced non-small cell lung cancer (NSCLC). Although several ICI options are available, the treatment regimen for NSCLC with large tumors (large NSCLC) is controversial and the efficacy of anti-CTLA4 antibody is unclear. We thus investigated potential biomarkers for CTLA-4 blockade.
Methods
We examined the correlation between tumor diameter and treatment duration in advanced NSCLC patients treated with anti-PD-1 antibody in our institution. In addition, we evaluated the ratio of tumor-infiltrating CD8+ T cells and regulatory T (Treg) cells in small and large NSCLC using immunohistochemical staining. Finally, we investigated the efficacy of treatment containing anti-CTLA4 antibody against large NSCLC.
Results
We found a negative correlation between tumor diameter and treatment duration in patients treated with anti-PD-1 antibody. Immunohistochemical staining revealed that Treg cell infiltration was significantly higher in large NSCLC tumors than in small tumors. We obtained a remarkable tumor reduction in patients with large NSCLC with an ICI regimen including anti-CTLA4 antibody.
Conclusions
Anti-PD-1 antibody might be less effective for large NSCLC due to the infiltration of Treg cells. Therefore, for large NSCLC, it might be appropriate to select a treatment with anti-CTLA4 antibody, which is expected to deplete Treg cells via antibody-dependent cellular cytotoxicity activity.
The epidemics of substance misuse and suicide in Syria: casualties of protracted conflict and political instability
Authors: Rayes Diana , Almoshmosh Nadim , El-Khani Aala , Alkhalil Munzer , Basha Sara , Fouad Fouad , Hilal Mohammad Abo , Abbara Aula 
Published: September 2022

Abstract
Background: The Syrian conflict has resulted in significant displacement and increase in humanitarian needs within the last decade. Reports of increased prevalence of substance misuse and deliberate self-harm among internally-displaced Syrians are concerning, particularly given barriers to care for these conditions due to cultural stigma and legal repercussions for those reporting them. The aim of this study is to provide an overview of prevalence, risk factors and health services available for substance misuse and deliberate self-harm in Syria as well as share findings from a workshop with Syrian mental health stakeholders exploring current challenges with regards to these conditions.
Methods: A scoping review was conducted using key search terms regarding substance misuse and suicide and/or self-harm inside Syria. These findings were supplemented by a discussion among 25 Syrian mental health stakeholders, including psychologists, psychiatrists, public health, and policy professionals to highlight key challenges and identify locally appropriate solutions.
Results: Data regarding the prevalence of substance misuse and self-harm inside Syria among internally displaced populations varies greatly quality and accuracy. Substance misuse and deliberate self-harm, including suicide, are considered stigmatised and at times, criminalized, in Syria, leading to massive underreporting of prevalence, as well as underutilization of available treatment, which is also limited. The health system response in Syria, which has been compromised by a decade of conflict, is not prepared to cope with increasing rates of mental health disorders and particularly, substance misuse (i.e. Captagon) and instances of self-harm. Key suggestions from the workshop include the following: a) use of telepsychiatry and telepsychology interventions b) adaptation of WHO interventions c) multi-year investment and prioritisation of MHPSS programs and d) utilizing family skills interventions as a key tool in the
prevention for substance abuse and self-harm, while embedding social and cultural sensitivities into interventions.
Conclusions: Though current evidence gaps around substance misuse and deliberate self-harm in Syria remain, with the current socio-political climate in Syria, alongside significant shortfalls in funding for health, there is a present, urgent need to address these neglected MHPSS concerns. Emphasis must be placed on the needs of vulnerable populations including IDPs, war injured, children and teenagers.