bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of Temporal and Spatial Evolution Characteristics of Land Subsidence in Western Songnen Plain Using Multisource Remote Sensing
Authors: Zheng Lianjing , Wang Qing , Wang Zeyu , Wang Fengyan , Cao Chen 
Published: June 2022

Abstract
The exploitation of underground fluid is an important factor leading to land subsidence. The effects of mining depth, frequency, and mode on land subsidence are also different. The objective of this study was to develop a multisource method—including optical remote sensing interpretation, Interferometric Synthetic Aperture Radar (InSAR) technology, and unmanned aerial vehicle (UAV)—to reveal the long-term temporal and spatial evolution law of subsidence characteristics driven by groundwater and oil extraction, as well as to reveal the formation mechanism and seasonal response law of land subsidence under the action of different driving factors. In this paper, we select the western region of Jilin Province located in Songnen Plain as the study area. The subsidence funnels in the study area are distributed in a porphyritic manner, and the distribution of the subsidence funnels has a certain correlation with the distribution of the pumping wells. In farmland areas, the subsidence is mainly caused by pumping groundwater. The annual land subsidence rate in the study area is -3.14 mm/a, and the maximum deformation rate in the study area is -22.05 mm/a. The subsidence is affected by the season, shown by the fact that it rises in the dry season and decreases in the rainy season. The subsidence in the west of Songnen Plain is caused by oil pumping and groundwater pumping, and groundwater pumping is dominant. The exploitation of underground fluid transfers the pressure borne by water or oil to the soil skeleton so as to increase and consolidate the effective stress of the soil layer and lead to land subsidence. The continuous observation of the surface in the western area of Songnen Plain is helpful to guide the safe production of agriculture and industry and ensure the smooth development of local industry and agriculture.
Design of H-IoT Based Pregnancy Monitoring Device in Free-living Environment
Authors: manivannan jeevitha , K Preethi , A Bhagyaveni M 
Published: June 2022

Abstract
The revolution of Internet of Things (IoT) technology has paved the way for designing modern health care systems. Among the various applications of IoT, health care monitoring is need of the hour. This paper deals with the design of a Handheld Pregnancy Monitoring Device (HPMD) that comprises of a wearable abdominal patch and mobile application (Pregnancy Health Monitoring app) interfaced with the analytical Health-Internet of Things (H-IoT) platform. This aids in non invasive measurement of the pregnant woman’s uterine contractions, the Fetal Heart Rate (FHR) and the fetal presentation to detect true labor and to ensure fetal safety. Here, the abdominal patch includes the Electromyography (EMG) electrodes that capture the uterine contractile activity and the Fetal Electrocardiogram (FECG) electrodes that capture the fetal electrical activity for monitoring FHR and fetal presentation. Now, the data captured from these electrodes are analyzed using the H-IoT platform by using various methods. A Level crossing rate method is used in H-IoT to differentiate true labor from Braxton-Hicks (false labor). In addition, FHR is retrieved using Discrete Wavelet Transform (DWT) and fetal position is determined by cross correlating the obtained FECG with the existing FECG template. Further, decisions from the analyzed parameters are displayed in the Pregnancy Health Monitoring (PHM) mobile app which includes the live visualization plots of the EMG and FECG signals for monitoring the mother and fetus health condition in the free-living settings.
The Korean Undiagnosed Diseases Program Phase I: Expansion of the Nationwide Network and the Development of Long-term Infrastructures
Authors: Kim Soo Yeon , Lee Seungbok , Woo Hyewon , Ko Young Jun , Shim Youngkyu , Park Soojin , Jang Se Song , Lim Byung Chan , Ko Jung Min , Kim Ki Joong , Cho Anna , Kim Hunmin , Hwang Hee , Choi Ji Eun , Kim Man Jin , Moon Jangsup , Seong Moon-Woo , Park Sung Sup , Choi Sun Ah , Lee Ji Eun , Kwon Young Se , Sohn Young Bae , Kim Jon Soo , Kim Won Seop , Lee Yun Jeong , Kwon Soonhak , Kim Young Ok , Kook Hoon , Cho Yong Gon , Cheon Chong Kun , Kang Ki-Soo , Song Mi-Ryoung , Kim Young-Joon , Cha Hyuk-Jin , Choi Hee-Jung , Kee Yun , Park Sung-Gyoo , Baek Seung Tae , Choi Murim , Chae Jong-Hee , Ryu Dong-Sung 
Published: June 2022

Abstract
Background
Phase I of the Korean Undiagnosed Diseases Program (KUDP), performed for 3 years, has been completed. The Phase I program aimed to solve the problem of undiagnosed patients throughout the country and develop infrastructures, including a data management system and functional core laboratory, for long-term translational research. Herein, we share the clinical experiences of the Phase I program and introduce the activities of the functional core laboratory and data management system.
Results
During the program (2018–2020), 458 patients were enrolled and classified into 3 groups according to the following criteria: I) those with a specific clinical diagnosis that required direct testing (32 patients); II) those with a clinical diagnosis with genetic and phenotypic heterogeneity (353 patients); and III) those with atypical presentations or diseases unknown to date (73 patients). All patients underwent individualized diagnostic processes based on the decision of an expert consortium. Confirmative diagnoses were obtained for 242 patients (52.8%). The diagnostic yield was different for each group: 81.3% for Group I, 53.3% for Group II, and 38.4% for Group III. Diagnoses were made by next-generation sequencing for 204 patients (84.3%) and other genetic testing for 35 patients (14.5%). Three patients (1.2%) were diagnosed with nongenetic disorders. The KUDP functional core laboratory, with a group of experts, organized a streamlined research pipeline covering various resources, including animal models, stem cells, structural modeling and metabolic and biochemical approaches. Regular data review was performed to screen for candidate genes among undiagnosed patients, and six different genes were identified for functional research. We also developed a web-based database system that supports clinical cohort management and provides a matchmaker exchange protocol based on a matchbox, likely to reinforce the nationwide clinical network and further international collaboration.
Conclusions
The KUDP evaluated the unmet needs of undiagnosed patients and established infrastructure for a data-sharing system and future functional research. The advancement of the KUDP may lead to sustainable bench-to-bedside research in Korea and contribute to ongoing international collaboration.
Characteristics of Treatment of Copper Mine Wastewater by Ozone Advanced Oxidation
Authors: lu miaoqiang , Wei Qihang , Zhang Ping , Chen Jincheng , Wu Renya , Feng Fei , Wei Linsheng 
Published: June 2022

Abstract
Copper mine wastewater is a rather tough environmental issue. An efficient and effective method is still expected. Ozone advanced oxidation technology is applied to treat copper mine wastewater in this paper. A systematical investigation is performed and the degradation mechanism is revealed. Experimental results show ozone can effectively degrade COD meanwhile all pollutants indexes can meet the strict emission requirement. There are two interesting discoveries in copper mine wastewater treatment process by ozone advanced oxidation. One is COD change with ozone aeration time. COD rapidly decreases initially, followed by a small recovery, but then decreases slightly. The dramatical decrease in the first several minutes results from the oxidation of residual flotation reagents, humic acid-like and soluble microbial product-like. The small recovery is because these substances of protein-like and humic acid-like are oxidized to small molecules. The last slight decrease is due to the further oxidation of these small molecules. Another is ammonia nitrogen change in fluctuations with ozone aeration time. The oxidation CwHxNyOz in residual flotation reagent Xanthate leads the first ammonia nitrogen increase and the following first decrease, respectively. It is followed by another increase and decrease. The second increase is owing to these relatively stable nitrogenous organic matters of protein-like and fulvic acid-like are oxidized to ammonia nitrogen. The last reduce results from the further oxidation of ammonia nitrogen. In a word, ozone advanced oxidation is a promising technology for copper mine wastewater treatment.
Teachers' perception of school functionality and participation of children with cerebral palsy
Authors: Tavares-Netto Afonso Rodrigues , Wiesiolek Carine Carolina , Dantas Diego de Sousa , de Melo Marianna de Fátima Araújo , de Mattos Rebeca Maranhão , Melo Renato S. , Ferraz Karla Mônica 
Published: June 2022

Abstract
Purpose: To analyze the perception of teachers about the functionality and school participation of children with cerebral palsy (CP). Methods: Descriptive, exploratory, observational study with a mixed design of quantitative and qualitative approach, carried out with 14 teachers, who were interviewed in a questionnaire model, based on the International Classification of Functionality, Disability and Health (ICF). The reports were transcribed and quantified based on the domains and codes of the second level of the ICF, for better analysis. Results: The reports pointed out aspects that facilitate the participatory process of children through the attitudes of the people who make up the school support network. However, the challenges to school inclusion were highlighted, related to issues of recreation, leisure and mobility, restricting participation and environmental barriers, as for services, systems and policies related to construction, architecture, health, and education. Conclusion: Such aspects reinforce the importance of interventions focused on the individuality of the child, taking into account the entire context in which he lives, and not just the intervention limiting the modification of the affected body structures and function. Thus, the teachers interviewed focused on participation in mobility and recreation activities linked to interdisciplinary work, qualification of education professionals, and readjustments in school infrastructure as challenges for greater participation of children with CP.
Pilot Study for Posterior Quadratus Lumborum Block in Myomectomy: A Randomized Controlled Trial
Authors: Little Christopher , Naim Natale , Grogan Tristan , Yu Steve , Chia Pamela 
Published: June 2022

Abstract
BackgroundUterine fibroids affect 20-40% reproductive age women in the United States. Gynecologic surgeons now perform roughly 65,000 myomectomies each year. The quadratus lumborum block (QLB) is an effective block for laparoscopic pelvic surgery, urologic surgery, hip hemiarthroplasty, femoral neck fracture repairs, and cesarean sections. No clinical trials have yet assessed the QLB in patients receiving laparoscopic myomectomies. We evaluated the effectiveness of the posterior QLB in reducing post-operative pain and morphine milligram equivalent (MME) consumption in patients undergoing laparoscopic myomectomies. MethodsThis was a single center, single-blinded, randomized, controlled study conducted from February 5, 2019 and June 6, 2020. Twenty-seven patients undergoing laparoscopic myomectomy were enrolled, and randomized to the QLB group or control group. Patients in the QLB group received bilateral posterior QLBs. Patients in the control group did not receive a block. MME use at 24 hours following surgery was our primary outcome. MME at other timepoints, as well as post-operative numeric rating scale (NRS) pain score and patient satisfaction were our secondary outcomes. Results are presented as mean ± SD.ResultsWe recruited 26 patients, 21 of whom were included in our analysis. Total mean MME consumption was similar between the QLB group and the control group (24.7 ± 8.5 mg, vs. 26.8 ± 12.1 mg respectively; p=0.653). MME consumption was also similar among both groups for intraoperative consumption, total PACU consumption, and at 6, 24, and 48 hours after the end of surgery. Mean NRS pain scores were reduced at 6 hours postoperatively in the QLB groups compared to the control groups (2.0 ± 2.0 vs. 4.6 ± 2.3 respectively; p = 0.007). There was no difference in NRS pain scores at any other time point. ConclusionThis pilot study provides evidence the QLB may be useful in patients receiving laparoscopic myomectomies. Further studies with a larger sample size will be valuable to determine the effectiveness of this block in laparoscopic myomectomy. Trial RegistrationOur trial is registered with ClinicalTrials.gov on May 2, 2019 with the corresponding identifier NCT03935815
Recommended System Optimization in Social Networks based on Cooperative Filter with Deep MVR Algorithm
Authors: Gao Qiang 
Published: June 2022

Abstract
Today, social networks have become very popular due to their high usage in communicating with each other. But this popularity requires the development of backend to communicate with each other. Hence, a topic called identifying users is created by making recommendations or propositional systems, and so on, link prediction. The most important issue is the new users' social networks, so that they can offer suggestions. In this research, we tried to provide a system of recommendations for introducing new users to previous users and vice versa based on the principles of machine learning. The proposed method is that the data is entered into the program and then the keywords are extracted from them. Then a sampling between the data is performed based on the Pearson and Cronbach method. In the process of extraction operations along with diminishing dimensions, selection and finally extraction of the best features is done using the cooperative filter which named here based on deep learning- Modified Vector Rotational (MVR) algorithm and its operators. In the following, due to the lack of probabilistic and statistical training of the Deep and Reinforcement Learning with random structure that is used to select users and also to offer users with respect to the tastes of the extracted, there is an optimization algorithm for MVR consider the best features with training. In the following, a series of evaluation criteria have been used to ensure the proposed approach, indicating the appropriate results of the proposed method.
Plant topping effects on the yield and active ingredient content of rhizome of Polygonatum cyrtonema, and analysis of functional composition, Antioxidant Activity its Waste
Authors: Tang Wenwen , Chen Yuan , Guo Fengxia , Li Qian 
Published: June 2022

Abstract
Polygonatum cyrtonema is a perennial plant, and it has long been used in traditional Chinese medicine for food and medicine. The medicinal part of Polygonatum cyrtonema is the underground rhizome; however, the aerial part has not been studied so far for its medicinal activity. To promote the growth of underground rhizomes, the topping of aboveground plants of Polygonatum cyrtonema has been conducted. To understand the effect of the topping of aerial parts on the yield and medicinal components of rhizomes, the present study was conducted. Also, the chemical constituents, antioxidant, and in vitro hypoglycemic activities of the aerial stem, leave, and flower parts of Polygonatum cyrtonema were analyzed. The results showed that compared to the control (CK) treatment, the topping of the aerial part increased rhizome weight gain coefficient (3.43) significantly than the CK treatment (2.63). Moreover, the topping of the aerial part induces the biosynthesis of bioactive compounds. As such, the polysaccharide content in the rhizome (8.80%) and the total saponin content (37.60 mg/g) was significantly (P < 0.01) higher than CK treatment. The contents of total phenols and total flavonoids in PCL and PCF were significantly (P < 0.01) higher than those in rhizomes; however, the polysaccharide content (10.47%) in PCR (whole rhizome) was higher than that in PCS (3.65%), PCL (5.99%), and PCF (4.76%) content. The protein and amino acid contents in PCS, PCL, and PCF were higher than those in rhizomes. The protein and amino acid contents in PCS, PCL, and PCF were higher than those in rhizomes. PCS, PCL, and PCF showed strong antioxidant activities (DPPH, ·OH, ABTS, and FRAP), which were better than traditional medicinal parts ( the rhizome). To sum up, the topping measures can improve the rhizome yield of Polygonatum cyrtonema and the medicinal components of the rhizomes, which can be applied to improve production. The stems, leaves, and flowers had a much stronger antioxidant activity and higher the total polyphenols, flavonoids, proteins, and amino acid content. Therefore, stems, leaves, and flowers of Polygonatum can be fully developed according to different needs. they are typically used in animal feed, food storage and cosmetics.
Partial Otubain 1 deficiency compromises fetal well-being in allogeneic pregnancies despite no major changes in the Dendritic cell and T cell compartment
Authors: Stutz Annika , Nishanth Gopala , Zenclussen Ana Claudia , Schumacher Anne 
Published: June 2022

Abstract
Objective
Pregnancy is characterized by well-defined immunological adaptions within the maternal immune cell compartment allowing the survival of a genetically disparate individual in the maternal womb. Phenotype and function of immune cells is largely determined by intracellular processing of external stimuli. Ubiquitinating and deubiquitinating enzymes are known to critically regulate immune signaling either by modulating the stability or the interaction of the signaling molecules. Accordingly, if absent, critical physiological processes may be perturbed such as fetal tolerance induction. Based on previous findings that mice hemizygous for the deubiquitinating enzyme otubain 1 (OTUB1) do not give rise to homozygous progeny, here, we investigated whether partial OTUB1 deficiency influences fetal-wellbeing in a syngeneic or an allogeneic pregnancy context accompanied by changes in the dendritic cell (DC) and T cell compartment.
Results
We observed increased fetal rejection rates in allogeneic pregnant OTUB1 heterozygous dams but not syngeneic pregnant OTUB1 heterozygous dams when compared to OTUB1 wildtype dams. Fetal demise in allogeneic pregnancies was not associated with major changes in maternal peripheral and local DC and T cell frequencies. Thus, our results suggest that OTUB1 confers fetal protection, however, this phenotype is independent of immune responses involving DC and T cells.
Impact of Beverage Temperature on Consumer Preferences for Black Coffee
Authors: Ristenpart William , Cotter Andrew , Guinard Jean-Xavier 
Published: June 2022

Abstract
We recently performed a systematic investigation of consumer preferences for black coffee versus key brewing parameters, including total dissolved solids, extraction yield, and brewing temperature (Cotter et al., Journal of Food Science, 2021). An experimental goal in that work was for participants to taste the coffee at a beverage temperature of 65°C, but the large sample size of more than 3,000 individual tastings, combined with natural variations in the brewing and cooling processes, meant that coffees were assessed over a normally distributed range of temperatures between 56 and 71°C. Here we use those data to provide a more detailed analysis of the impact of beverage temperature on consumer acceptance of the coffee. Using a 5-point just-about-right (JAR) scale, we find that a majority of consumers (>50%) assessed the temperature as JAR at all temperatures tested up to 70°C. A substantial fraction of consumers, approximately 6 to 12%, assessed the coffee as too cold over the range 56 to 68°C. Only above 70°C did a majority of consumers assess the coffee as too hot and none assessed it as too cold, albeit with 40% still assessing it as JAR. Complementary analyses indicate that beverage temperature over this range had little impact on assessments of the adequacy of flavor intensity, acidity, and mouthfeel, but did correlate slightly with overall liking and purchase intent. Overall, the results suggest that temperatures over the range of 58 to 66°C maximize consumer acceptance, and that 68 to 70°C is the minimum temperature range at which no consumers will assess black coffee as too cold.
Determination of 20 neonicotinoid insecticides and their metabolites in infant foods by a modified QuEChERS method combined with HPLC-MS/MS
Authors: Guo Liqiang , Li Kai , Zhang Jinling , Tian Guoning , Ke Wang , Li Yajing 
Published: June 2022

Abstract
A rapid, effective, and reliable method for the simultaneous detection of 20 neonicotinoids and their metabolites in infant foods has been developed using liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). To improve the accuracy and precision of the method, different extraction solvents, extraction methods, and adsorbents were evaluated to achieve a better recovery and clean-up effect. Under optimized conditions, the samples were extracted with acetic acid acidified acetonitrile/ethyl acetate by ultrasonication, and then were cleaned with reduced graphene oxide@Fe3O4 (rGO@Fe3O4) and primary and secondary amine (PSA) through a QuEChERS step. A matrix-matched calibration method was applied for quantification. In three different food matrixes (vegetable & fruit cookies, grain rice cereals, and vegetable purees), all the target compounds showed good linearity, both with values of r2 > 0.99. The average recovery of all neonicotinoids ranges from 68.0%~106.5% (vegetable & fruit cookies), 70.4%~105.4% (grain rice cereals), and 71.9%~107.4% (vegetable purees). Relative standard deviations were all < 15% for intraday and interday precision. The values of limit of detection and limit of quantification were, respectively, ranging from 0.02-0.35 μg kg-1 and 0.1-1.0 μg kg-1. The presented method was applied to the analysis of real samples.