bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antioxidant vitamin attenuated the carcinogenesis effect of HPV16E7 by inactivating PI3K/AKT/TERT axis
Authors: Wang Hongyan , Wang Hao , Wen Jinglin , Wang Meihan , Guo Liyuan 
Published: October 2022

Abstract
Objectives: The aim of this study is to explore the effect of β-carotenoids on the HPV related cervical cancer.
Methods: Western blot was used to detect the protein expression. CCK8 and transwell assays were used to determine proliferation and metastasis ability of cancer cell.
Results: In this study, we found HPV16E7 promoted the development of cervical cancer by elevating the expression of TERT. TERT was upregulated in tumor tissue and positively associated with the progression of cervical cancer. The patient with higher expression of TERT predicted to have poorer prognosis. HPV16E7 enhanced the expression of TERT by activating PI3K/AKT signaling pathway.
Conclusions: Antioxidant vitamin β-carotenoids could inhibit the effect of HPV16E7 on the expression of TERT by inactivating the PI3K/AKT signaling pathway and suppressed the cervical cancer progression induced by HPV16E7.
Brief Ornithology of Blue-throated Barbet (Psilopogon asiaticus)
Authors: SAHA SANJIT , SAHA RINKI 
Published: October 2022

Abstract
Last year in India lockdown started on 23rd March, 2020 due to pandemic situation of COVID-19 for the outbreak of SARS-CoV-2 at first for 18 days and then extended for phase by phase with the imposition of strong restrictions for movement. During that time lockdown was already there in several countries of the World. So, all the people of Global village faced the situation like house arrest. All the social, official, commercial and institutional activities were prohibited for the people. Apart from the household work most of the people got themselves busy in the unproductive work like watching TV and using mobile phone. For morning and evening work we were compelled to use only the lawn and backyard premises of the household. During our walk we have interacted with 35 species of birds. We became fond of Blue-throated Barbets (Psilopogon asiaticus) during our walk and documented the roosting, nesting, foraging behaviour of the Blue-throated Barbets. We have found great camouflage adaptation of Blue-throated Barbets and several times only bird call/song helped us to sight the bird. We have recorded bird calls/songs and all the data related to sighting and audio were submitted to ebird platform. Spectrograms of audios were analyzed to decipher the bird call/song. Lockdown helped us to explore fundamental lessons of ornithology.
Mass-Energy Equivalence in Bound Three-Nucleon Systems
Authors: Filikhin Igor , Suslov Vladimir , Vlahovic Branislav 
Published: October 2022

Abstract
The mass defect formula reflects the equivalence of mass and energy for bound nuclear systems. We consider the three-nucleon systems 3H and 3He assuming the neutron and proton to be indistinguishable particles (AAA model) or taking into account realistic masses for neutrons and protons (AAB model). We discuss the disagreement between the AAA model and the mass defect formula, which is related naturally to the AAB model. Also, we demonstrate that ignoring the neutron-proton mass difference leads to the uncertainty for AAA calculations of several keV that overlap the realistic calculations accuracy estimated before in the literature. To show another manifestation of the mass-energy equivalence, we perform AAA realistic calculations varying nucleon mass and scaling the depth of pair potential to show the mass-energy compensation effect. Comparing the results of different authors, we show that the contribution of attractive three-body potential to the Hamiltonian can be compensated by increasing the nucleon mass. For the binding energy calculations, we apply the differential Faddeev equations.
A Novel Fusion Technique for GeoEye-1 Satellite Imagery
Authors: Elshora Mohamed 
Published: October 2022

Abstract
Color distortion is the main weakness of the current fusion techniques, which occurs because of radiometric differences between panchromatic (PAN) and multispectral (MS) images. In this study, a novel fusion technique was developed to merge the PAN and MS images of the GeoEye-1 satellite and produce superior fused images without color distortion. This technique proposes reducing the difference in radiometry between the PAN band and the MS bands by using only the parts of the MS bands inside the area of the PAN band. Therefore, modification coefficients were used for the MS bands in the definition of the intensity (I) equation based on their overlapping areas with the PAN band. As the reflectance of vegetation is high in the NIR band and low in the RGB bands, this technique suggests using an additional coefficient for the NIR band in the definition of the I equation to add the correct effect of vegetation. This coefficient is variable for all types of land cover based on the percentage of the agricultural areas within the image, which leads to significant and stable performance for all types of land cover. This study aims to evaluate the performance of this technique by a comparison with five standard fusion techniques: fast-intensity-hue-saturation, principal component analysis, Gram Schmidt fusion, hyper-spherical color space, and Ehlers fusion. Three datasets of GeoEye-1 satellite PAN and MS images in Tanta City, Egypt, with different land cover classes (agricultural, urban, and mixed areas), were used in this study. The output fused images were compared with the original PAN and MS images by statistical analysis and visual inspection. The proposed fusion technique demonstrated great efficiency in producing fused images of superior spatial and spectral quality for all types of land cover.
Leniency Policies and Cartel Success: An Experiment
Authors: Kim Jeong Yeol , Noussair Charles 
Published: October 2022

Abstract
Cartels are often fought by granting leniency, in the form of forgiveness of penalties, to whistle-blowers. This study employs a laboratory experiment to compare leniency programs that differ with respect to fine size and whether a second whistle-blower may apply for leniency. The results show that leniency does not affect the probability that a cartel forms, but is effective in exposing cartels and thereby inhibiting cartel success. Higher fines are more effective, but allowing leniency to a second whistle-blower is no more effective than granting leniency to only one whistle-blower.
Regulating Antimicrobial usage in Livestock Farming: Innovative and interdisciplinary solutions
Authors: NATHAN MUGENYI , PRIZE NINSIIMA , Byakika-Kibwika Pauline , Clarke Rose Nanyonga 
Published: October 2022

Abstract
Antimicrobials have been used extensively in Livestock production. The overuse and misuse of antimicrobials has resulted in the development of drug resistant pathogens that is Antimicrobial Resistance (AMR). The emergence and spread of drug resistant pathogens has resulted into AMR and has continued to threaten our veterinary and health care systems. The most alarming situations include the rapid global spread of multi-and pan-resistant bacteria which have been referred to as “superbugs”. These have caused infections that are un-treatable with the available medicines in our health care and veterinary settings.AMR is one of the top ten global health and development threats facing humans and animals according to the World Health Organization hence the need for urgent multisectoral action. Antimicrobials are medicines used for prophylaxis, treatment and prevention of infections in animals, humans and plants. They comprise of antibiotics, antiviral, antifungal and antiparasitics. Antibiotics are increasingly losing their effectiveness as drug-resistance spreads globally resulting into difficulty in treating infections, death of animals and humans. In this paper, we addressed some of the innovative solutions based on an interdisciplinary perspective. We discussed the fundamental concerns for defining policies and strategies to mitigate AMR in Livestock farming, structured a basis for AMR policies and strategies and the key actors in Antimicrobial decision systems.
Titanium (IV) μ-Oxo Complex Supported by Phenoxyimine Ligand: Synthesis, Crystal Structure Characterization, DFT and Molecular Docking Studies
Authors: Sajjan Vinodkumar P. , Gurubasavaraj Prabhuodeyara M , Pujari Vikram , Inamdar Sanjeev , Mukerjee Nobendu 
Published: October 2022

Abstract
A new crystalline complex [Ti{La}] has been synthesized in the reaction of titanium butoxide with a phenoxyimine ligand in a 1:1 stoichiometry in toluene at room temperature under a nitrogen atmosphere. The complex has been characterized by various spectroscopic and analytic techniques. A suitable crystal analysed by X-ray diffraction establishes the formation of a stable binuclear μ-oxo-complex with a hexacoordinate titanium centre. The crystal shows a monoclinic system with space group C 1 2/c 1. X-ray crystal structure analysis reveals that this complex has a rhomboidal Ti-O-Ti core and exhibits a C2 symmetric conformation with distorted octahedral geometry. Density functional theory (DFT) calculations using B3LYP with the basis set of 6-31+G have been performed on the activated species, giving insights into the frontier orbitals and mulliken charge analysis, which showed good correlation with the experimental findings. Additionally, in silico molecular docking of ligand and complex was carried out against HER2 inhibitor kinase. The complex exhibits high binding energy of ΔGb = -19.7 kcal/mol with the active pocket of HER2 (PDB:7JXH) than the ligand ΔGb = -8.5 kcal/mol.
Correlation between red blood cell distribution width (RDW) and disease activity in patients with Rheumatoid arthritis
Authors: kudsi Maysoun , baydoun Bassam , almoallem Moataz 
Published: October 2022

Abstract
Background:
Rheumatoid arthritis is a systemic disease. The active and chronic forms of the disease can cause articular deformities. A lot of clinical and laboratory indicators were used to assess its remission or/and flare. A higher value of red cell distribution width was found in some autoimmune diseases like Rheumatoid arthritis, so it may be used to evaluate the disease activity in these patients.
Objective:
To assess the relationship between elevated RDW and the activity of Rheumatoid arthritis in Rheumatoid arhtritis patients compared with healthy control.
Methods:
A cross-sectional/case-control study was conducted on 84 rheumatoid arthritis patients,diagnosed according to the 2010 American College of Rheumatology/European League Against Rheumatism criteria, attending Damascus Hospital and 84 healthy population, matched in age and gender. Red cell distribution width was compared between the two groups, and between patient groups, according to the presence of anemia.Red cell distribution width value was also compared between the patient group itself, according to the presence of anemia, and the disease activity by using the disease activity 28 score/erythrocyte sedimentation rate. Demographic Data include:age and gender were collected, and data of the disease include: disease durations, disease activity were only collected from the patients. Laboratory tests such as complete blood count reactive protein and erythrocyte sedimentation rate were all measured.
Results:
The age of the patients was 42 ± 8  yr., while it was41.10 ±10  yr., in the control group (P= ).0.274 % were females 85.7% and were males 14.3% in patients group, while, in the control group were female78.58% and were males21.42%.
Higher red cell width value was found in patients when compared with controls, and a positive correlation between it and the activity of the disease was also found in patients.
Discussion
Red blood cell distribution width (RDW) is a test that measures the difference in the volume and size of red blood cells and is routinely used to diagnose anemia.
In our study that included 84 patients and span over a year, we found a statistical relationship between RDW measures and rheumatoid arthritis activity (DAS28-ESR)
Other studies have shown that inflammatory diseases including rheumatoid arthritis affected the hematopoiesis process, as these studies have shown that high levels of inflammatory cytokines such as IL-1, IL-6, and TNF-alpha inhibit the activity of erythropoietin by eliminating the sensitivity of erythroid progenitors towards erythropoietin thus causing immature blood cells to flow into the bloodstream resulting in high RDW.
Chronic inflammation also causes red blood cell life by increasing its degradation thus causing differences in red blood cell sizes.
Conclusions:
In patients with rheumatoid arthritis, the elevation of red cell distribution width may express the disease activity in Rheumatoid arthritis patients.
Effect of renewable energy on the technical efficiency of manufacturing firms in Cameroon
Authors: Koumou Etienne Landry 
Published: October 2022

Abstract

The objective of this paper is to investigate the effect of renewable energy on the technical efficiency of manufacturing firms in Cameroon. The data for the study comes from the Annual Enterprise Surveys (AES) of the National Institute of Statistics (INS) for the period 2012–2019. The method used is the one-step Stochastic Frontier. The results show that the effect of renewable energy on the technical efficiency of manufacturing firms in Cameroon is negative in some cases and positive in others. Renewable energy has a negative effect on the technical efficiency of agro-food and chemical firms. The effect is, on the contrary, positive in the printing and textile sectors, as well as in the wood sector. On the other hand, the technical efficiency of manufacturing firms is around 40.57%. This last result means that manufacturing firms in Cameroon can increase their production by 59.43%, while keeping the same level of production factors.
Population Genetic Structure of Culex quinquefasciatus in Osogbo Metropolis, Nigeria inferred from Mitochondrial COI sequences
Authors: Aremu Harun K. , Adediji Adedapo , Iyoha Alex , Ajayi Ebenezer , Oyafajo Lateefah , Adekale Idris , Musa Dickson , Azeez Luqmon , Adeleke Monsuru 
Published: October 2022

AbstractCulexmosquito is a major vector of some deadly and debilitating diseases that include lymphatic filariasis and West Nile fever. Understanding the population genetics structure plays a crucial role in unravelling the epidemiological pattern of mosquito-borne disease and facilitating effective vector control measures. Hence, this study investigated the population genetic structure ofCulexmosquitoes within selected urban areas in Osogbo, Osun State, Nigeria using the mitochondrial cytochrome c oxidase subunit I (mtCOI) DNA region. Mosquito samples were collected from twelve (12) sampling sites in different locations in Osogbo, Osun State and identified on the basis of morphological characteristics followed by mtCOIgene amplification and sequencing.Cx. quinquefasciatuswere observed to be significantly distributed in sampling locations. The results of sequence alignment showed stable genetic structure and a shared inter-spatial haplotype owing to the significantly low haplotype diversity (Hd= 0.154; π = 0.112). The TCS network revealed that the dominant haplotype H1 shares a connection with haplotype H19. Tajima’s D values were negative for the sequence datasets with p > 0.05; implying genetic equilibrium of theCOIsequences in all populations. Phylogenetic tree analysis showed sharedCOIsequences and are present in the same subclusters. Intra and interspecies were observed to have varying nucleotide and haplotype diversities. High percentage similarities of theCOIregion may be linked to human activities that have enhanced gene flow and conferred beneficial mutation attributes. Thus, continuation of this trend could be disadvantageous to the vector control mechanisms forCx. quinquefasciatusin the selected population.
Quantitative assessment of resilience engineering in process industries through a novel multi-attribute group decision-making algorithm using interval type-2 fuzzy sets
Authors: Bamdad Shahrooz 
Published: October 2022

Abstract
Nowadays, the promotion of technology has increased the complexity of socio-technical systems, which has led to severe disasters. Human errors and defects in components of a system have previously been recognized as the most important causes of accidents. Still, recent studies have emphasized that the causes of accidents, especially in complex socio-technical systems (CSS), depend on organizational factors, functional changes, and combining a set of unexpected events. With the transition from the traditional static approach to systems, and due to the two features of high interconnectivity and the complexity of modern systems, a new approach called resilience engineering (RE) has been introduced. On the other hand, sophisticated socio-technical systems have a high level of uncertainty that its modeling requires considering tools for dealing with this kind of intricate uncertainty, such as interval type-2 fuzzy sets (IT2FS). In this paper, focusing on process industries, a new algorithm based on multi-criteria group decision-making for evaluating departments of a process industry from RE using the concept of type-2 fuzzy sets is presented. To do this, by introducing the RE criteria in process industries, their weights are calculated as incomplete information received from the decision-makers (DMs). The incompleteness of information is due to the uncertainties in the evaluation of criteria. Then different alternatives are ranked using IT2FS. It is shown that the presented algorithm is relatively consistent with other approaches, and besides simplicity, it has good stability for dealing with different weights for the criteria.
ANKARA ETNOGRAFYA MÜZESİ’NDEKİ İKİ GÜMÜŞ KİTAP KAPAĞI ÜZERİNE GÖRÜŞLER
Authors: YAŞAR Fatma , MİMİROĞLU İlker Mete 
Published: October 2022

Altın, gümüş ve bakır levhalar üzerine yapılan süslemelerle zenginleştirilen kitap kapakları ökaristi ayininin vazgeçilmez bir parçası olarak karşımıza çıkar. Erken Hıristiyan toplumların fildişi diptiklerden etkilenerek üretilen kitap kapakları zaman içinde gelişim göstererek farklı tasarımlarla geliştirilmiştir. Değerli taşlarla ve zarif işçilikle süslenen kitap muhafazaları sanatsal bakımından değerlidir. Bu özel kitap kapakları kütüphanelerde kullanılmasından ziyade kiliselerde düzenlenen ayinlerde liturjik bir parçası olarak kullanılmıştır. Farklı dönemlerde yeni tasarımlarla karşımıza çıkan kitap kapakları gerek malzeme gerek üzerinde taşıdığı ikonografi bakımından farklı dönemler içerisinde gelişmiştir. Lakin hiçbir zaman amacının dışında kullanılmamış, her zaman ökaristi ayininin vazgeçilmez bir parçası olarak kullanılmıştır. Eski ve Yeni Ahitten alınan konularla biçimlendirilen kapaklarda çoğunlukla İsa’nın çarmıha gerilmesi ve diriliş sahneleri işlenmiştir.
Araştırma konumuz olan Lola Törenhan Hanım’ın tarihi eser hazinelerinden çıkan kitap kapakları 1984 yılında Ankara Etnografya Müzesi’ne devredilmiştir. Müze deposunda yer alan iki gümüş kitap kapaklardan biri kitabeli olup Post-Bizans dönemine aittir, diğerinde ise herhangi bir kitabe bulunmamasına karşın eserin üslupsal özellikleri benzer örneklerle karşılaştırıldığında Ermeni kitap kapaklarını andırdığı düşünülmektedir. Çalışmadaki amacımız, bu gününe kadar çeşitli yayınlarda ve müze koleksiyonlarında ayrıntılı olarak incelenmemiş olan kitap kapaklarının gelişimini saptamak ve elde edilen sonuçlar ışığında Ankara Etnografya Müzesi’ndeki gümüş kitap kapaklarını tanıtmak sanat tarihi alanına bir parça da olsa katkı sağlayabilmektir.
Sources of maintenance of the first Franciscan Observans monasteries in Kingdom of Poland (to the middle of the 16th century)
Authors: Sitnik Aleksander Krzysztof 
Published: October 2022

Artykuł podejmuje zagadnienie uposażenia zakonników żyjących według reguły zabraniającej przyjmowania pieniędzy i rzeczy mających jakąkolwiek wartość materialną. Również oni zabiegali o utrzymanie klasztorów. Różne były, jak się okazuje, źródła dochodów klasztorów. Ignorowany przez nich pieniądz, będący w XIII w. synonimem bogactwa, stał się, w miarę upływu czasu, środkiem płatniczym używanym przez wszystkie warstwy społeczne. Z tego względu autorzy ustaw i konstytucji zakonnych łagodzili na przestrzeni wieków surowe nakazy św. Franciszka z Asyżu, podzielając tym samym opinię franciszkanów na temat ubóstwa.
Implementasi Kebijakan Surabaya Cross Culture International sebagai Upaya Pengembangan Pariwisata di Kota Surabaya
Authors: Hikmah Dzakiyah Adalatul , Khusnul Prasetyo  , Eka Arum Pramestya  
Published: October 2022

Every government, regardless of size, must constantly adapt to a changing environment and direct a change in a positive direction in which development is a key to do so. The tourism industry is one of the few development fields that has consistently excelled. The purpose of the Surabaya City Tourism and Culture Office, which bears the nickname "City of Heroes", is to increase tourist attraction through artistic and cultural performances. In 2018, the Ministry of Tourism designated Surabaya as the winner of the “Best City” in Yokatta Wonderful Indonesia Tourism Awards. The city government has made several initiatives to promote tourism. The Surabaya City Government carried out preventive efforts in the form of the 2019 annual Surabaya Cross-Cultural International Themed Folk Art Festival. The focus of this research is to explain the implementation of Surabaya Cross Culture International activities and to describe the collaboration between government actors (government, civil society, and the private sector). This research is a descriptive qualitative research with interviews and literature review as the data collection techniques. The resource persons in the study were the Cultural Affairs Staff of the Surabaya City Culture and Tourism Office, the Head of Surabaya Local Parliament for the 2014–2019 period, and the Ning Representative for the City of Surabaya in 2019. The results of this study showed success eventhought there were several technical constraints in implementing the policy indicators proposed by Van Meter and Van Horn, namely the objectives and standards of the policy, the implementers’ attitude, resources, the implementers’ characteristics and communication between organizations and the economic, social, and political environment. In addition, the collaboration carried out by the government, the private sector, and the community shows synergy to support the successful implementation of Surabaya Cross Culture International.
The Criteria of Neologism in Visual Media
Authors: Ahmad Trifa Omar , Kaka Hama Ata Ali 
Published: October 2022

Neologism is a new branch of linguistics. Less tackling in dealing with the standards and foundations of this science in the Kurdish language is found, so (Standards of neologism in visual media) is preferred as a title for this study in which its standards, foundations and fields related to the Kurdish lexicon were presented, as well as analyzing the effectiveness of this science in the Kurdish language based on models from visual media. Further, it was found that despite the effectiveness of the rules producing the word and the term, still the Neologisms has an important role in the production and innovation of new words.