bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trait anxiety and coping strategies among healthcare professionals during the COVID-19 pandemic
Authors: Smaoui N. , Bouaziz A. , Kraiem M. , Omri S. , Feki R. , Bouali M. Maalej , Charfi N. , Thabet J. Ben , Zouari L. , Maalej M. 
Published: February 2022

IntroductionThe current pandemic wave of COVID-19 has become a global threat. Healthcare professionals (HCP), by being on the front line in managing this pandemic, confronted high levels of stress and traumatic experiences.ObjectivesThe aims of our study were to evaluate the trait-anxiety among Tunisian HCP and its impact on coping strategies.MethodsA cross- sectional descriptive and analytic study conducted among Tunisian HCP during November and December 2020. The data was collected by an online questionnaire distributed through social media. The trait-anxiety was assessed using the “General Anxiety questionnaire of Spielberger” (STAI-Y-B) and the “Ways of coping checklist revised (WCC-R) questionnaire” identified three types of coping (problem-focused, emotion-focused and social-support seeking).ResultsParticipants were 135 HCP (71 males and 64 females) and aged from 24 to 61 years old (average age 31.98 years; SD 6.59 years). Of HCP involved in the study, 61.5% were single, 36.3% were married and 2.2% were divorced. Seventy-two of them had a trait-anxious. As a coping style, 85.2% of participants used problem-focused style, 88.9% of them used emotion-focused style and 63% of them used social support seeking style. The analysis of WCC-R showed that anxious HCP used emotion-focused coping more than non anxious HCP (p= 0.028). However, there was no significant difference in problem-focused or social support seeking coping styles and presence of trait-anxiety.ConclusionsIn our study, we find that the most anxious Tunisian HCP focused on emotions strategies. Personality traits play on attitudes of coping strategies.DisclosureNo significant relationships.
Anxiety among healthcare professionals during the COVID-19 pandemic: Predictive role of social support
Authors: Bouaziz A. , Smaoui N. , Kraiem M. , Bouali M. Maalej , Omri S. , Feki R. , Thabet J. Ben , Zouari L. , Charfi N. , Maalej M. 
Published: February 2022

IntroductionThe COVID-19 pandemic may cause elevated levels of anxiety in healthcare professionals (HCP). Identifying factors that could help maintain mental health especially social support could be helpful in facing this stressful situation.ObjectivesThe aim of this study was to asses the relationship between the trait-anxiety and perceived social support among Tunisian HCP in the current pandemic wave of COVID-19.MethodsA cross- sectional descriptive and analytic study conducted among Tunisian HCP during November and December 2020. The data were collected by an online questionnaire. The trait-anxiety was assessed using the “General Anxiety questionnaire of Spielberger” (STAI-Y-B). We used the “Social Support Questionnaire” to measure availability and satisfaction regarding perceived social support.ResultsParticipants were 135 HCP, and aged from 24 to 61 years old (average age 31.98 years). The sex ratio was 1.1 (71 males and 64 females). Of HCP involved in the study, 61.5% were single, 36.3% were married and 2.2% were divorced. The average scores of availability and satisfaction regarding perceived social were 7.79 (SD=3.56) and 28.41 (SD=6.75), respectively. Seventy-two of the HCP had a trait-anxious. Analysis showed that social support satisfaction scores were significantly lower in trait-anxious HCP (p<0.001). However, there was no significant difference in the score of availability according to trait-anxiety (p=0.49).ConclusionsOur study highlighted the existence of a deficit on perceived social support satisfaction among trait-anxious Tunisian HCP. Perceived social support as a determinant of trait anxiety should be the focus of social work in this period.DisclosureNo significant relationships.
Perceived characteristics of life situations during the COVID-19 pandemic
Authors: Bityutskaya E. , Kheruvimova A. , Mirzamedova T. , Skvortsova A. , Spitsyna A. , Lebedeva N. 
Published: February 2022

IntroductionThe COVID-19 pandemic situation is seen as an intense stressor. However, people process it differently.ObjectivesThis study aims to examine the connection between life situation perception and the desirability of life changes the pandemic caused.MethodsAdult participants (n=144; 01.04.2020–01.06.2020) answered open-ended questions about their current life situation experience and rated the desirability of life changes on a 10-point scale (see table 1). Content analysis and Pearson’s χ2 criterion were used.Table 1Changes’ desirability-5-4-3-2-1+1+2+3+4+5Group 1Group 2Group 3Group 4Rejecting changesAccepting changesResultsWe annotated the participants’ responses. The content of life situations was categorized into restrictions, losses, difficulties (negative responses), acquisitions (positive responses), neutral, and ambivalent responses. Life goals were categorized into an approach to the desired outcome, avoidance of hassles, preservation of status quo, self-development, and return to prepandemic life. χ2 analysis confirms the differences between content-types and goal-types categories in 4 groups of participants: χ2(15)=43.62; p=0.002 (content); χ2(12)=27.23; p=0.01 (goals). The desirability of changes was positively linked with the ambivalent responses and responses containing self-development goals or approach-to-desired-outcome goals; and was negatively linked with the responses containing restriction-type situations and avoidance goals. Only the respondents accepting changes reported acquisitions; only the respondents rejecting changes reported a return to prepandemic life goals.ConclusionsPerceived characteristics of life situations are closely connected with the desirability of life changes during the pandemic. Funding: The reported study was funded by RFBR, project number 20-013-00838.DisclosureNo significant relationships.
COVID-19 psychological impact in patients with depressive disorder: Differences based on their age
Authors: Gil E. Martín , Valtueña-García M. , González-Blanco L. , Santo F. Dal , Moya-Lacasa C. , Vázquez C. Álvarez , Martínez-Cao C. , García-Alvarez L. , García-Portilla M.P. , Saiz P.A. , Bobes J. 
Published: February 2022

IntroductionCOVID-19 pandemic and lockdown have provoked a considerable psychological impact in Spain. Some studies have reported greater psychological impact in the younger population. To date, no previous study has focused on depressive disorder (DD) patients based on their age.ObjectivesTo describe the psychological impact on DD according to age.MethodsCross-sectional study of an online survey available from 19 to 26 March 2020. Out of a total of 21207 respondents, 608 (2.9%) reported suffering from DD (mean age ±SD = 41.2 years±14.07 [18-82], 80.6% women). The subsample (608) was divided according to age, “youngsters” <45 (57.4%)/ “elders” ≥45. DASS-21 and IES scales were employed. Statistical analyses: Chi-square, t-Student test.ResultsBoth groups did not differ (p>0.05) in sex, having COVID-19 symptoms, having family/friends infected, or income changes. While youngsters were single more frequently (68.8% vs 14.3%, χ² = 179.7, p<0.001), elders had somatic illness more frequently (64.8% vs 39.7% χ² =30.401, p<0.001). Youngsters obtained higher scores in depression (4.69 vs 4.1, T=5.413, p<0.001), anxiety (2.86 vs 1.97, T=5.249, p<0.001) and stress (4.48 vs 3.17, T=6.355, p<0.001) DASS-21 subscales, as in intrusive (3.42 vs 3.05, T=1.984, p=0.048) and avoidant (4.64 vs 4.11, T=3.056, p=0.002) IES scores.ConclusionsDespite the group of elders with depression being more vulnerable to severe COVID-19 disease and presenting more frequently somatic comorbidities, younger depressive patients suffered more from depressive, anxiety, stress and avoidant symptoms and intrusive thoughts, in line with previous reports in the general population.DisclosureNo significant relationships.
Telework during COVID-19 outbreak: Impact on mental health among Italian workers
Authors: Bertino V. , Nisticò V. , D’Agostino A. , Gambini O. , Demartini B. 
Published: February 2022

IntroductionSince February 2020, the outbreak of COVID-19 has spread to several countries worldwide, including Italy, leading to an uptake of telework.ObjectivesWe aim to evaluate the psychopathological impact of teleworking during the COVID-19 pandemic in Italy, identifying mental health determinants among home-based workers.Methods804 participants completed an online survey, including the psychometric scales “Depression, Anxiety and Stress Scale – 21 items” (DASS-21) and the “Insomnia Severity Index” (ISI). Teleworkers were also asked to provide information about their current work routine, home environment and clinical history.ResultsAt the DASS-21, 30% of the participants presented pathological levels of depression, 20.8% of anxiety and 30.7% of stress. At the ISI, 5% appeared to suffer from insomnia. Respondents with psychological and physical frailties, greater social isolation or inadequate working spaces manifested higher levels of psychiatric symptoms. Moreover, we also find a correlation of these symptoms with occupations in education. Telework was broadly appreciated and 87% of respondents expressed a willingness to maintain access to this arrangement.ConclusionsOur results document that about a third of our sample manifested psychopathological symptoms while teleworking during the COVID-19 outbreak in Italy. However, telework itself does not seem to be directly associated with increased psychiatric symptoms, which were instead exacerbated by COVID-19-related stressful circumstances, as well as by constitutional and social determinants of health. Going forward, authorities should promote adequate measures in order to guarantee a healthy approach to teleworking.DisclosureNo significant relationships.
Transcultural validation of the “regulation of emotions questionnaire” among Tunisian university students
Authors: Bouguira E. , Ouali U. , Alaya M. Ben , Zgueb Y. , Nacef F. 
Published: February 2022

IntroductionThe regulation of emotions is a psychological process covering the capacity of inhibiting, maintaining or modulating emotions to create a coherent psychological functioning and to enable the individual to live in adequacy with his or her environment.ObjectivesThe aim of the study was to develop an Arabic version of the “Regulation of Emotions Questionnaire-2” (REQ-2T) from Phillips & Power, 2007, and to validate it in a sample of Tunisian university students.MethodsThis is a validation study conducted in a sample of 384 Tunisian university students to whom we administered the REQ-2T, the DASS-21 questionnaire and a sociodemographic questionnaire. We tested face and content validity, reliability, and construct validity of the Arabic version of the REQ-2.ResultsFace and content validity were satisfying. The internal consistency was average, with Cronbach’s alpha coefficient ranging from 0.44 to 0.65. The inter-dimensional correlation reflected statistically significant and logical correlations within the REQ-2T. Temporal stability was satisfying with a variable concordance of 0.65. Exploratory analysis revealed four factors similarly to the original version of the questionnaire. Statistically significant correlations were found between the REQ-2T and its external validator (DASS-21).ConclusionsThe REQ-2T demonstrated good psychometric properties, thus this scale can be reliably used as a measure of emotion regulation in the Tunisian population.DisclosureNo significant relationships.
Why does transcultural consultation matter?
Authors: Quintão A. , Santos C. , Urzal M.D. , Donas-Boto I. , Azevedo F. , Lemos M.M. , Coelho F. , Vian J. 
Published: February 2022

IntroductionPsychiatrists should be aware of the new challenges and needs that globalization poses.ObjectivesTo highlight the need for a culturally sensitive approach to mental health.MethodsNon-systematic review of “cultural consultation” on PubMed.ResultsMost people assume a direct connection between pathophysiology and clinical symptoms. However, evidence shows that the translation of pathophysiology and psychopathology into specific symptoms is mediated by cognitive processes and social interactions, which reflect models/practices specific to our culture. Patients focus on specific aspects of being sick, reinforced by cultural narratives or to fit expectations. Thus, people from different cultural backgrounds might have trouble communicating; cultural idioms of distress can be misinterpreted. The role of structural violence bestowed upon cultural minorities, which leads to discrimination and social exclusion, has extensively been studied as a risk factor for mental illness. Furthermore, ignoring cultural differences and diversity has been shown to contribute to healthcare disparities, hampering access to care and diminishing the quality of care received. In Canada, the Cultural Consultation Model provides cultural expertise, either by evaluating patients (preferably accompanied by the referring doctor, a translator and cultural mediator) for 1-3 sessions, providing recommendations to the referring doctor; or providing consulting to a referring doctor or organisation, through general guidance or discussion of specific cases.ConclusionsIn an evergrowing globalization process, we will inevitably have more contact with patients from culturally distinct backgrounds. To provide the best care, we must be aware of the ways in which culture can shape symptom expression, and take into account cultural explanations and preferences.DisclosureNo significant relationships.
Value-meaning formations in mentally ill patients with a religious worldview
Authors: Borisova O. , Kopeyko G. , Gusev V. , Gedevani E. , Vladimirova T. 
Published: February 2022

IntroductionIt is necessary to consider the religious worldview and spiritual needs of patients with mental illness in the course of psychotherapy and rehabilitation.ObjectivesThe explication of value-meaning formations (VMF) in mental patients with a religious worldview.MethodsG. Kelly’s methodology of personal constructs (Method of Triads, Hinkle’s laddering technique, the assessment repertory grid by F.Fransella&D.Bannister) and statistical analyses were applied.Results1. The structure of the value-meaning formations (VMF) of patients with religious worldview was characterized by its integrity, which is prerequisite for coping. 2. Opposite, patients with absence of religious belief had substantial destruction of integrity and plurality of relationships between VMF. 3. The content of the VMF of mental patients with religious worldview and healthy believers had similarities. 4. In the content of VMF meta-values were: 1. active aspiration to God and the realization of own existence; 2. material well-being in the earthly world; 3. “unselfish” ability to get along without causing harm; 4. feeling of inner confidence.ConclusionsMental disease affects VMF of believers and unbelievers in different way. In unbelievers, the structure of VMF in the course of disease significantly changes. In believers, the disease does not destroy the basis of VMF and allows to keep safe the key elements. The stability of VMF in the believers may be explained by the meaningfulness of life. The concepts of “health” and “disease” are included in the worldview of believers, in the general context of their spiritual, psychic and physical life.DisclosureNo significant relationships.
They are not real patients
Authors: Aparicio T. Jiménez , De Andrés Lobo C. , Adame C. Vallecillo , De Llano De La Viuda M. Queipo , Valera G. Guerra , Ramírez A. Gonzaga , Cerejeira J. Gonçalves , Carrasco I. Santos , Meseguer C. Capella , Vázquez E. Rodríguez 
Published: February 2022

IntroductionCognitive depressive disorder (or depressive pseudodementia) is a condition defined by functional impairment, similar to dementias or other neurodegenerative disorders, in the context of psychiatric patients. It is important to consider a differential diagnosis in patients with cognitive impairment.ObjectivesPresentation of a clinical case of a patient with depression with psychotic symptoms who presents cognitive impairment.MethodsBibliographic review of the differential diagnosis between cognitive depressive disorder and real dementia by searching for articles in PubMed.ResultsWe present a 51-year-old woman, previously diagnosed with adjustment disorder (with mixed anxiety and depressed mood) and unspecific anxiety disorder, who was admitted to the hospital due to delusional ideation of harm and Capgras syndrome, ensuring that her relatives had been replaced and the rest of the patients were not real patients, but actors who conspired against her. The MRI (Magnetic Resonance Imaging) was strictly normal (tumors or acute injuries as stroke or hemorrhage were discarded), and a MoCA (Montreal Cognitive Assesment) test was performed to screen any cognitive impairments (obtaining a score of 19/30, with language fluency and abstraction particularly affected). It would be convenient to repeat the test when this episode and the psychotic symptoms are resolved or improved.Conclusions1. Some patients may have cognitive impairment in the context of a mood disorder. 2. A differential diagnosis and follow-up of these patients should be performed to assess prognosis, reversibility and treatment. 3. Depressive cognitive impairment may precede the development and establishment of a dementia or neurodegenerative picture.DisclosureNo significant relationships.
Hyperoxia in depression
Authors: Belmaker R. , Bloch Y. , Shvartzman P. , Romem P. , Bersudsky Y. , Azab A. 
Published: February 2022

IntroductionSeveral studies of normobaric hyperoxia in some neurological conditions have demonstrated clinical benefits. Oxygen enriched air may increase oxygen pressure in brain tissue and have biochemical effects such as on brain erythropoietin gene expression, even in patients without lung disease.ObjectivesThis pilot, randomized, double-blind study examined the efficacy of normobaric hyperoxia as a treatment for depression.MethodsFifty-five consenting patients aged 18-65 years with mild to moderate depression were included in the study. Participants underwent a psychiatric inclusion assessment and a clinical evaluation by a psychiatric nurse at baseline, 2 and 4 weeks after commencement of study intervention. Participants were randomly assigned to normobaric hyperoxia of 35% fraction of inspired oxygen or 21% fraction of inspired oxygen (room air), through a nasal tube, for 4 weeks, during the night. Patients were rated blindly using the Hamilton Rating Scale for Depression (HRSD); Clinical Global Impression (CGI) questionnaire; Sheehan Disability Scale (SDS).Results
The present study showed a significant improvement in HRSD (p<0.0001), CGI (p<0.01) and in SDS (p<0.05) among patients with depression who were treated with oxygen-enriched air, as compared to patients who were treated with room air. In CGI, 69% of the patients who were treated with oxygen-enriched air improved compared to 23% patients who were treated with room air.ConclusionsThis small pilot study showed a beneficial effect of normobaric hyperoxia on some symptoms of depression.DisclosureNo significant relationships.
Physical training for patients with depression and anxiety - a randomized controlled study
Authors: Zhai Q. , Freund-Levi Y. , Horn A. , Fridenberger A.-C. , Lager E. , Montgomery S. , Persson J. 
Published: February 2022

IntroductionPharmaceutical treatment and psychotherapy constitute the most common treatment methods for depression and anxiety. Physical training has been shown to have comparable effect to cognitive behavioral therapy in treatment of mild to moderate depression and anxiety. Physically active individuals also show lower risks to develop depression and relapse in depression.ObjectivesThe objectives are to evaluate how physical activity can affect depressive and anxiety symptoms, by examining biomarkers in the blood and from the gut and also by measuring cognitive functions. Hopefully, this can lead to new treatment strategies for patients with depression and anxiety.Methods102 patients are randomized to two groups and undergo 12 weeks intervention as add-on to standard outpatient psychiatric treatment. The first group will participate in physical training three times per week and the other group will receive relaxation therapy on a weekly basis. Daily activity intensity will be measured before and at the last week of intervention with an accelerometer. Blood and faeces sample collection, symptom grading by clinician together with self-rating scales and cognitive screening will be performed at baseline, week 12 and one year of follow-up. The cognitive screenings are performed digitally in cooperation with Mindmore.ResultsThe RCT is currently recruiting patients at the Department of Psychiatry of Örebro University Hospital.Conclusions
The project aims to be holistic in its approach, combining the defining clinical psychiatric symptoms in patients who have both depression and anxiety with the finding and evaluation of new biomarkers from blood and gut to improve cognitive functions.DisclosureNo significant relationships.
Esketamine in patient with treatment resistant depression: Outcome of the temporary authorization for use programme in France
Authors: Wattinne E. Gaudre , Mekaoui L. , Rothärmel M. , Codet M.A. , Bouju S. 
Published: February 2022

IntroductionEsketamine nasal spray has been developed for patients with treatment resistant depression.ObjectivesA cohort Temporary Authorization for Use (ATUc) allowed to collect for a 6-month period the first data in real lifeMethodsOn 02/08/2019 the French National Agency for Medicines and Health Product Safety granted an early access program for Esketamine nasal spray framed by a specific protocol for patients without therapeutic alternatives. Each treatment request was approved based on inclusion and exclusion criteria. Clinical evolution, treatment management and safety were then spontaneously reported by psychiatrists.Results
From 09/23/2019 to 03/25/2020, 66 patients were treated. The median age was 53 years and 41 (62.1%) were females. At treatment request, 52 patients (79%), presented a severe current depressive episode based on clinical judgment. The median duration of the disease was 12.2 years and the current episode was 2.6 years. Since the beginning of the current depressive episode, all patients (66) were prescribed ≥2 antidepressants (mean 4.2). Esketamine was initiated in a complete hospitalization setting in 27 patients (55.1%) and in day hospitalization in 22 patients (44.9%).Safety profile was consistent with the one described during clinical study. The most frequently adverse events reported (>10%) were dizziness, sedation, sleepiness, anxiety and dissociation. Most of them appeared after treatment administration and were transient.ConclusionsATUc ended on 12/18/2019 after Marketing Authorization granted by European Medicines Agency. Data reported by French psychiatrists are the first collected in this specific population and provide descriptive information on patient characteristics, burden of disease; Esketamine management and practical use at hospital levelDisclosureData analysis performed by RCTs and poster conception coordinated by Medergy and funded by Janssen