bluuebunny/crossref_metadata_2025_split huggingface dataset:
Technology and its interventional value in patient-reported outcomes in cancer research, what is next?
Authors: Mendoza Luis 
Published: October 2022

For cancer patients, health-related quality of life (QOL) is a critical aspect of care management decision-making. In some cases, clinicians have even prioritized QOL over survival in patients with advanced cancer. Over time, patient-reported outcomes (PRO) have gained prominence in cancer research to capture aspects of a patient's health condition, reported directly by the patient through a questionnaire through scales validated in different moments. PROs are currently used as a research tool in clinical trials for cancer drug development to monitor and assess the psychological and cognitive well-being of patients and detect significant symptoms. In addition to QOL, several studies have suggested that PROs also improve patient outcomes and satisfaction. Retrospective analyses have shown that QOL and its early palliative care are a prognostic factor for survival in cancer patients. Although, such results were not confirmed by others who have reported after a systematic review of 24 controlled trials a limited statistically significant impact of PRO, and that the effect sizes of interventional PROs were small to moderate.
A palpable depression
Authors: Goutama Ivany Lestari , Hendsun Hendsun , Lestari Eva 
Published: October 2022

Several studies have shown that patients with depression, anxiety and stress have a higher ratio in developing atrial fibrillation (AF), with higher proportion occurring in patients with recurrent episodes of AF which are related to severity of disease and increased mortality ratio. We aim to discuss the case of AF caused by mental disorder to examine its relationship and impact in patient’s clinical outcomes. A 70 years-old-man came to clinic with palpitation five days before admission. He often cries and has not been able to sleep since his wife died three months prior. He admits to have neither hope nor desire to do his usual activities or even start new activities. Vital signs show BP 140/90 mmHg, pulse 150x/m, RR 20x/m, SpO2 98%. Cardiopulmonary examination revealed irregular S1-S2. ECG shows premature atrial contraction which evolved to asinus rhythm with HR 150x/minute, AF and incomplete right bundle branch block a months after the first ECG was examined. Depression-Anxiety-stress scoring-42 (DASS-42) was conducted in this patient. Results shows the patient has very severe depression, intermediate anxiety and severe stress. Mental disorders lead to increased etiology of cardiac remodeling factors due to degeneration and sympathetic stimulation, which then induced the AF. Further research is needed to examine whether psychiatric treatment can prevent AF in improving quality of life, healthy behavior and awareness for managing mental health.
Effectiveness of Virtual Reality (VR) technology towards pain management during initial fixed orthodontic procedures: A case-control study
Authors: Kamboj Ashish , Bindhani Bikash Ranjan , Mohanty Pritam , Seth Subhas , Mohanty Debapreeti , Samir PV 
Published: October 2022

The goal of this research is to see how effective virtual reality (VR) is in reducing discomfort during early fixed orthodontic operations. The research comprised 70 individuals, all of whom were between the ages of 15 to 18 years randomly divided into two groups- research group (n=35) and the control group (n=35). Patients in the experimental group received a virtual reality headset and watched interesting movies during orthodontic procedures, while those in the control group received regular care. The VR headgear was placed over the patient's eyes as the dental procedure began in the study group, whereas the controls group's eyes were kept open as they viewed the clinic and dental procedures going on around them. After adopting virtual reality movies before and after dental treatments, there was a statistically significant difference in pain levels between the control and study groups. The mean pain ratings during orthodontic treatment were 8.6 and 6.3 in the control and study groups, respectively. Following orthodontic treatment, the control and study groups reported mean pain levels of 7.4 and 6.7, respectively. VR is found to be an effective method in pain alleviation during initial fixed orthodontic procedures.
Post orthodontic periodontal evaluation of patients with different removable retainers: Hawleys Vs Essix
Authors: Kumar Rathin , Misra Vaibhav , Joshi Divya , Yadav Ashish , Attri Sonal , Johnson Steffi 
Published: October 2022

Prevention of unwanted post-treatment changes remains one of the biggest challenges in orthodontics. Retention using removable appliance is important, which can alter the oral hygiene and oral microbial flora, overall increase in the Streptococcus mutans can lead to caries formation which can lead to a missing tooth that can spoil the overall appearance of the patient. 24 post orthodontic subjects were divided in to two groups and group I was given Essix retainer and Group II was given Hawleys Retainer, Supra gingival plaque collected and bacterial colony count done using digital colony counter OHI-S and PI are recorded at T0 (start of treatment) T1 (30 days) T2 (60 days). Essix group has a significant increase in the streptococcus mutans count OHI-S and PI scores are higher for hawleys retainer group. This study advocates the use of a better appliance which along with aesthetics can also ensure better oral hygiene Care should be taken to provide detailed hygiene instructions for both appliance and teeth.
3D biomechanical intrusion effects of infra zygomatic bone screws and temporary anchorage device on total maxillary dentition in treatment of vertical maxillary excess: A FEM study
Authors: Kumar Avinash , Karanam Sudheer , Baba Fareeduddin MD 
Published: October 2022

Many studies have reported on the application and clinical efﬁciency of full arch maxillary dentition intrusion mechanics; however, studies about biomechanical effects such as stress, strain, and displacements on the teeth and the surrounding tissues are limited. The objectives of study was to evaluate and compare the stress distribution and displacement of total maxillary dentition under intrusion mechanics using a three-dimensional finite element analysisA three-dimensional finite element model was constructed based on computed tomography scan data, and it served basic model. The geometric model was converted to finite element model using Altair HyperMesh software. Model A with pre-adjusted edgewise appliance (PEA) setup and Model B with occlusal Splint setup was evaluated and compared for von mises stress distribution and displacement of total (full arch) maxillary dentition by using three dimensional finite element analysis; with force delivered from infrazygomatic screws and miniscrew. Force levels for Model A and Model B includes a total of 300grams of intrusive force (each side) on maxillary posterior segment from IZC bone screw and 100grams of intrusive force on anterior segment from miniscrew.In the model A; with PEA setup reinforced with two trans-palatal arches, highest von Mises stress of 0.970 Mpa was produced on second molar roots followed by molar roots and premolars and central and lateral incisors roots. In the Model A, maximum intrusive values was seen on crown tip of central and lateral incisors (8.671µm), and lowest displacement values on second molars (2.230µm). Similar pattern of von Mises stress distribution and displacement was observed in the Model B. Model A and Model B provided an effective en masse vertical control of the full arch maxillary dentition. Higher intrusion displacement values were seen in anterior segment than the posterior segments
Efficiency of using a short-acting β2-agonist for the relief of acute cold bronchospasm in asthma patients with cold airway hyperresponsiveness
Authors: Prihodko A. G. , Perelman J. M. 
Published: October 2022

Excessive sensitivity of the respiratory tract to physical and chemical environmental triggers can vary for many reasons, reducing the therapy effectiveness in a patient with asthma. Aim of the study was to investigate the effectiveness of a short-acting bronchodilator in patients with asthma for the relief of acute cold bronchospasm after a test of isocapnic cold air hyperventilation (ICHV). Material and methods. In 281 (161 women; 120 men, p > 0.05) asthma patients with cold airway hyperresponsiveness (CAHR), the change in airway patency (FEV1) and the efficacy of short-acting β2-agonists (SABA) after a 3-minute isocapnic hyperventilation with cold (–20 ºС) air. Results. According to clinical data, patients had persistent asthma, mean age 35 (26; 44) years, 49 % of patients smoked, ACT 16 (12; 20) points, FEV1 90.0 ± 1.0 % predicted, FEV1/VC 71.4 ± 0.6 %, the increase in FEV1 after inhalation of SABA (∆FEV1β) was 11.1 (5.1; 20.5) %. The change in FEV1 for the ICHV varied within –16 (–22.0; –12.0) %. The use of SABA after the IHCV showed different efficacy for relief of an attack of cold bronchospasm. The median value of ∆FEV1β after ICHV was 21.1 (11.6; 33.3) %, with a range of –48.6 to 108.2 %. In the general group, there was a direct relationship between the level of asthma control in terms of ACT points and the baseline FEV1 (Rs = 0.17; p = 0.007), MEF25-75 (Rs = 0.18; p = 0.008), ∆FEV1β in response to SABA (Rs = –0.17; p = 0.0104), as well as the severity of the bronchial response to the ICHV (Rs = 0.15; p = 0.014). The latter, in turn, correlated with ∆FEV1β after ICHV (Rs = –0.28; p < 0.0001) after HCI. Conclusions. There is a differentiated airway response to SABA after acute cold bronchoprovocation. The results obtained can serve as an important tool for phenotyping of asthma patients with CAHR for the medication correction of сold bronchospasm.
Preparing the upper gastrointestinal tract for an esophagogastroduodenoscopy to identify the source of acute bleeding
Authors: Ilkanich A. Ya. , Darvin V. V. , Ryzhikov M. G. , Oganian A. V. 
Published: October 2022

Esophagogastroduodenoscopy (EGDS) is the main way to diagnose bleeding from the upper gastrointestinal tract. Diagnostic accuracy of the study depends on the preparation. Aim of the study was to evaluate the preparation of the upper parts of the digestive tract in case of esophagogastroduodenal bleeding. Material and methods. The retrospective analysis of 2570 case histories was carried out. Gastric lavage through nasogastric tube was carried out in the main group (1299 patients). Preparation for the primary EGDS was not carried out in the control group (1271 patients). A comparison of the number of EGDS performed and the detection of the bleeding source in the control and the main groups as well as the period of investigation up to the detection of the bleeding source were performed. Results. EGDS without preparation of the upper gastrointestinal tract in case of acute bleeding and determination of the diagnosis is possible in 85,6 % of patients. Preparation of the upper gastrointestinal tract for EGDS prolongs the study period by 30–60 minutes, but allows establishing the diagnosis in 93.7 % of cases that is by 8.1 % more than without preparation.
Zombie i inni zarażeni, czyli obraz epidemii w literaturze popularnej
Authors: Górka Elżbieta 
Published: October 2022

Od dżumy do Eboli. Sposób przedstawienia wybranych chorób zaraźliwych w przykładowych tekstach literatury popularnej [From the plague to Ebola: The presentation of selected contagious diseases in popular literature texts] by Edyta Izabela Rudolf is a pioneering achievement in the Polish research field, opening scientific discourse on the image of an epidemic in popular literature. Published on the eve of the COVID-19 pandemic, the monograph also provides tools for the study of the newly created pandemic literature.
Taking into account the complexity of the research material, which lies on the borderline between the humanities, the social, and biological sciences, the author has quite rightly decided to include her study in the field of medical humanities. The chronological distribution of the extensive research material allowed for taking into consideration the broad historical and social context which influenced the shape of works created in subsequent eras.
Minor inaccuracies include the inappropriate use of terminology (such as the term topos) and the questionable assignment of the novel The Andromeda Strain to Chapter Three (it could easily have found its place in Chapter Four).
Despite these shortcomings, Edyta Rudolf’s work is a valuable monograph which provides tools for studying the image of contagious diseases in popular literature.
La estructura del equipamento urbano en los desarrollos habitacionales
Authors: Franco Muñoz Rodrigo , Carrillo Arredondo Aida Alejandra 
Published: October 2022

La ciudad se estructura como un sistema que debe estar integrado por varios subsistemas urbanos que se interconectan y entrelazan para su buen funcionamiento; El equipamiento urbano es una parte importante del engranaje de esta ciudad y por tanto es básico para el buen funcionamiento de cualquier ciudad.

Una urbanización debe funcionar como una unidad barrial y para lograr este objetivo es necesario estructurar el equipamiento urbano por núcleos desde los más inmediatos a la población, este es un primer nivel de proximidad correspondiente a los jardines del barrio, en un segundo nivel de los centros municipales y finalmente el centro del barrio. Lograr esta estructura es parte fundamental de una adecuada optimización de los recursos que la población necesita utilizar sin necesidad de utilizar el vehículo, lo cual está a favor de la sustentabilidad de una ciudad.

En estos centros de equipamiento urbano se construyen plazas para todos los grupos de edad, referentes a niños, adolescentes, jóvenes, adultos y adultos mayores, donde se establece la convivencia en los jardines barriales, los centros municipales y el centro barrial. Cada unidad de ellos satisface una cobertura, distancia y frecuencia en función de cada unidad de estos niveles de equipamiento. Planificación de la ubicación más adecuada para cada espacio e instalaciones construidas que respondan a una actividad específica según el grupo de edad. Estos usos de suelo deben responder a un estudio de compatibilidad.
Amazônia: as últimas línguas indígenas sobreviventes
Authors: Lima Ademar dos Santos , Sousa Rosineide Magalhães de , Mello Antonio Augusto Souza 
Published: October 2022

Neste artigo, apresentamos as línguas indígenas da Amazônia, as que já foram extintas, as que continuam sendo faladas e já registradas e as línguas dos povos indígenas isolados, com especial atenção a essas últimas línguas indígenas amazônicas brasileiras que restaram após mais de quatro séculos de colonização. Para a organização e discussão do estudo, dividimos as línguas em cinco categorias: vivas, extintas, mortas, debilitadas e revitalizadas. A metodologia utilizada foi de abordagem qualitativa e as técnicas empregadas foram de metapesquisa com foco na triangulação dos dados bibliográficos e de pesquisa etnográfica. O estudo constatou que há 36 famílias linguísticas e das 718 línguas indígenas que havia na Amazônia brasileira, apenas 26 são, ainda, faladas fluentemente e de forma interrupta por cerca de 5 mil ou mais falantes dentro de cada etnia, 438 foram extintas, 3 estão mortas e possuem apenas registros escritos, 243 estão debilitadas e são faladas por pequenos grupos e pessoas mais idosas, geralmente, acima dos 40 anos e 8 foram revitalizadas. Ou seja, reintroduzidas na prática de interação e comunicação da comunidade linguística. Abordamos neste trabalho, também, o conceito de cada uma dessas categorias de línguas indígenas e a situação em que cada língua se encontra dentro do contexto dessas categorias linguísticas.
Un proyecto curricular desde la comunalidad
Authors: Carmona Liliana Silva , Guzmán Lucero López , Dimenna Eva Alejandra , Solis Dafne Gonzalez 
Published: October 2022

Con el objetivo de estudiar a la Universidad Autónoma Comunal de Oaxaca (UACO) en un contexto de crisis estructural generalizada, a partir de la lucha de resistencia de las epistemologías locales; contemplamos el contexto de la Educación Intercultural, así como las condiciones del Estado de Oaxaca para indagar en la conformación de la UACO como proyecto curricular alternativo, porque consideramos que representa a grupos que históricamente han sido silenciados por los saberes occidentales, y que a partir de la resistencia de las poblaciones emerge como un proyecto alternativo curricular, que organiza y orienta la práctica, desde una experiencia comunal de los sujetos en los procesos de formación universitaria en el contexto de México, en el estado de Oaxaca y en la localidad de Santa María Colotepec. Palabras-clave: Universidad Autónoma Comunal de Oaxaca (UACO); Epistemologías Locales; Educación Intercultural.
Les ventes de bois des forêts publiques en 2021
Authors: Office national des forêts Département Commercial Bois 
Published: October 2022

Dans un environnement économique très porteur et une belle mobilisation en volume, le chiffre d’affaires bois des forêts publiques gagne 28 % à 538 millions d’euros en 2021. Les prix de tous les résineux, du Chêne et du Hêtre augmentent nettement alors que la crise du scolyte régresse et que le merrain ne se redresse qu’en fin d’année. Le prix unitaire apparent s’accroît de 14 %. Les volumes fournis en contrats d’approvisionnement progressent de 10 %.
SABERES E FAZERES DOS PROFESSORES DE GEOGRAFIA REFERENTES À EDUCAÇÃO AMBIENTAL NAS ESCOLAS ESTADUAIS DE ENSINO MÉDIO EM PORTO NACIONAL – TO
Authors: Miranda Artemiza Ferreira Soares , Bispo Marcileia Oliveira 
Published: October 2022

Este trabalho teve como objetivo analisar a relação entre as concepções dos professores de Geografia e sua prática docente no ensino médio, referente à Educação Ambiental nas Escolas Estaduais de Porto Nacional – TO, investigando quais os saberes que os docentes de Geografia possuem de Educação Ambiental e identificar os fazeres dos docentes de Geografia em Educação Ambiental. A metodologia foi fundamentada numa revisão de literatura acerca do tema estudado. Para isso, foi realizada uma pesquisa bibliográfica em livros, teses, dissertações e artigos sobre a importância das concepções e práticas dos professores de Geografia referente à Educação Ambiental nas escolas formais em Porto Nacional – TO, na rede pública estadual e também foram realizados entrevistas, questionários e observação das aulas dos professores. Os resultados obtidos oferecem uma visão de como tem se dado à práxis em Educação Ambiental na área pesquisada e a relação com a Geografia. A partir do arcabouço elaborado das concepções reveladas, foi possível formular algumas sugestões de intervenção em EA para as escolas pesquisadas. Ressalta-se que a importância desta pesquisa para a área está em contribuir para a reflexão sobre os saberes e fazeres que possam permear a EA e, também, pela contribuição que fornece, não ficando apenas no trato conceitual.
Multiple Imputation to Salvage Partial Respondents
Authors: Yamate Satoshi , Hamai Satoshi , Kawahara Shinya , Hara Daisuke , Motomura Goro , Ikemura Satoshi , Fujii Masanori , Sato Taishi , Harada Satoru , Harada Tetsunari , Kokubu Yasuhiko , Nakashima Yasuharu 
Published: October 2022

Background:Missing responses are common when Asian patients complete the Forgotten Joint Score-12 (FJS-12), which is widely used to evaluate total hip arthroplasty (THA). We aimed to provide orthopaedic researchers with a solution for handling missing values in such patient-reported outcome measures (PROMs).Methods:Patients who had undergone primary THA between 1998 and 2016 (n = 1,021) were investigated in 2020. The FJS-12 and 9 other PROMs, including questions related to Asian lifestyle activities, were administered. Risk factors for missing FJS-12 items were investigated. Partial respondents were matched with complete respondents; then, in each pair, the items not completed by the partial respondent were deleted from the responses of the complete respondent. Predictive mean matching (PMM) was performed in an attempt to recover the deleted items, using 65 sets of imputation models. After the missing values had been imputed, we explored patient characteristics that affected the FJS-12, using data from all complete and partial respondents.Results:A total of 652 patients responded to the survey (393 complete and 193 partial respondents). Partial respondents were older, more often female, and less active. Older respondents were more likely to skip items involving the bed, while those who reported a better ability to sit in the seiza style (traditional Japanese floor sitting) were more likely to skip items about chair sitting. The imputed FJS-12 value exhibited excellent reliability (intraclass correlation coefficient for agreement with the true scores, 0.985). FJS-12 values of complete respondents were significantly higher than those of respondents with 4 to 11 missing items (51.6 versus 32.8, p < 0.001). Older age was associated with higher FJS-12 values, which was revealed only via analysis of the multiply imputed data sets (p < 0.001).Conclusions:Analysis of only complete FJS-12 responses after THA resulted in a nonresponse bias, preferentially excluding older, female, and less active individuals and those with a traditional floor living style. Multiple imputation could provide a solution to scoring and analyzing PROMs with missing responses by permitting the inclusion of partial respondents.Level of Evidence:TherapeuticLevel III. See Instructions for Authors for a complete description of levels of evidence.
Surgical Correction of Neuromuscular Scoliosis Secondary to Congenital Zika Syndrome
Authors: O'Donnell Jennifer M. , Metz Lionel , Swarup Ishaan 
Published: October 2022

Case:
Congenital Zika syndrome (CZS) has been noted after the South American pandemic of Zika virus which peaked in 2015 to 2016, and the associated sequelae are still being described. Scoliosis has been noted in patients with CZS; however, there is a paucity of literature on the prevalence or management of scoliosis secondary to this condition. We report the case of a 5-year-old girl with severe neuromuscular scoliosis due to CZS that was managed with halo-gravity traction, followed by a growth-friendly construct.

Conclusion:
This case report highlights the need for more research focusing on the survivors of the Zika pandemic.