bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Qualitative, Multiperspective Inquiry of Multiple Sclerosis Telemedicine in the United States
Authors: Roth Erin G. , Minden Sarah L. , Maloni Heidi W. , Miles Zipporah J. , Wallin Mitchell T. 
Published: October 2022

ABSTRACT

BACKGROUND
Telemedicine has expanded access to high-quality, appropriate, and affordable health care for people with multiple sclerosis (MS). This study explored how the expansion of MS telemedicine is perceived and experienced by people with MS, health care providers (HCPs), and payers and policy experts (PYs).

METHODS
Forty-five semistructured interviews with 20 individuals with MS, 15 HCPs, and 10 PYs were conducted between September 2020 and January 2021. The interviews were recorded on a televideo platform, transcribed, and analyzed for themes using qualitative data software.

RESULTS
Interviews revealed the following 4 themes. Technology: Telemedicine increases access and convenience. Technical challenges were the most cited downside to telemedicine. Clinical encounters: Confidence in MS care via telemedicine varies. Virtual “house calls” have clinical benefits. Financing and infrastructure: Reimbursement parity is critical to utilization and expansion of telemedicine. Stakeholders are hopeful and fearful as infrastructure and business models begin to shift. Shifting expectations: The familiar structure of the office visit is currently absent in telemedicine. Telemedicine visits need more intentionality from both providers and patients.

CONCLUSIONS
Telemedicine is an efficient, convenient way to deliver and receive many aspects of MS care. To expand telemedicine care, many HCPs need more training and experience, people with MS need guidance to optimize their care, and PYs in the United States need to pass legislation and adjust business models to incorporate benefits and reimbursement for telemedicine health in insurance plans. The future is promising for the ongoing use of telemedicine to improve MS care, and stakeholders should work to preserve and expand the policy changes made during the COVID-19 pandemic.
Impact of a Virtual Wellness Program on Quality of Life Measures for Patients Living With Multiple Sclerosis During the COVID-19 Pandemic
Authors: Weinstein Sarah M. , Reilly Emily , Garland Nora , Zimmerman Vanessa , Jacobs Dina 
Published: October 2022

ABSTRACT

BACKGROUND:
Patients with multiple sclerosis (MS) were vulnerable to the effects of physical inactivity during the COVID-19 pandemic. As patients returned to in-person visits, providers reported seeing increased weakness, balance issues, falls, worsening pain, and spasticity. Social isolation also contributed to increased stress, depression, and anxiety. This study explored whether attending virtual wellness programs was associated with improvements in standard quality of life questionnaire scores for patients with MS.

METHODS:
The purposive convenience sample consisted of 43 patients in the treatment group and 28 in the control group. Patients in the treatment group attended 2 monthly programs for 6 months and completed a demographic questionnaire, the 36-Item Short Form Health Survey (SF-36), the Modified Fatigue Impact Scale, and the Medical Outcomes Study Pain Effects Scale (PES). Patients requested additional topics, resulting in 5 additional programs. The control group consisted of patients who chose not to attend the programs but agreed to complete the questionnaires.

RESULTS:
In comparing questionnaire responses (6 months minus baseline) among the participants in the treatment group, an association was found between higher meeting attendance and improvements in emotional well-being (P = .038), pain on the PES (P = .011), mindfulness on the SF-36 pain scale (P = .0472), and exercise on the PES (P = .0115).

CONCLUSIONS:
The results of this study suggest that a virtual wellness program may provide beneficial emotional support, physical exercise, and health promotion activities resulting in improved quality of life in people with MS. In addition, mindfulness and exercise programs may be beneficial in pain management.
Kant's Critique of Pure Reason: Aesthetics Inside and Outside of Transcendental Aesthetics
Authors: Kormin Nikolai Aleksandrovich 
Published: October 2022

The subject of the research is the features of Kant's "Critique of Pure Reason", which contribute to the methodological acquisition of aesthetic identity, they are generated through the transition to harmony of higher cognitive abilities, set the prospect of revealing how art is possible, and declare themselves in a specific experience of color and ideality of perfection and other concepts significant for aesthetics. Transcendental aesthetics, within which the first semantic images of aesthetics as a science and cultural form are formed, as a singular a priori of the history of art, as well as the structure of the coloristic discourse of criticism, reduces any objectivity of color and reveals the essential structures of its subjective experience. Kant, with one purely transcendental rhythm of reflection in the first Critique, revealed the conditions for the possibility of the aesthetic, raised the question of what makes all art possible; the transcendental undertaking itself manifested both timelessness and temporality behind their work in art.In the Critique of Pure Reason, the concept of perfection is analyzed outside of transcendental aesthetics, where a more or less definite description of perfection is given, which is directly related to the aesthetic facet of the transcendental meaning of the world. Its exceptional importance for understanding Kantian aesthetics is due to the fact that the metaphysics of perfection in late Kant allows us to rethink the critical approach to identifying the structures of aesthetic judgment in the third "Critique".
The Third Site: Blending Polyphonic Methodology and Epistemology
Authors: Aure Venke , Dahlsveen Mimesis Heidi 
Published: October 2022

This article discusses how art and academia can intervene in what the authors call the third site. The authors’ common ground lies in an interest in artistic encounters between people where art and academia bring new discoveries on both the personal and the professional level. The core of this article is the lecture performance in which the authors explore boundaries of the personal, academia and art. By using artistic, art-based, and scientific approaches, they explore how established positions in art and academia can blend polyphonic methodology and epistemology. In their performative writing they use this artistic competence as their starting point, using performativity as an active event that produces representations of lived lives, the production of existential empiricism. Their endeavour is to illuminate value-related and new questions through art making and establish an epistemological and methodological basis for working with art and academia. The authors believe that the blurring of borders between art and academia contributes to epistemological and methodological pluralism.
Through artistic experiences, academia becomes vital and varied, creating a diversity of ways in which knowledge and the meaning of life can be represented.
Co-designed Embroidery
Authors: Veiteberg Kvellestad Randi 
Published: October 2022

This article studies three phases in a project with embroidery and pieces of textile involving students in a specialized teacher training programme in design, arts, and crafts at OsloMet – Oslo Metropolitan University (OsloMet). In an incremental research project spanning over a six-year period the project was developed and changed systematically in collaboration with the students.
The embroidery project phases demonstrate how students are included in action research and how research-based teaching is completed in the first year of teacher education. The observed results from the projects all use photographs as documentation to analyse the organisation of the education and seeks to reveal differences between the methods of cooperation and collaboration. The research question concerns how these practice-based experiences in embroidery can become empirical data for research. The empirical data underline the role of the lecturer as both artist, researcher, and teacher in influencing the dynamics of the groups but also trying to nurture artistic outcomes. Furthermore, the experiences become part of critical reflections on the art teacher’s practice or perhaps in response to her professional development review.
Distorted body schema after mastectomy with immediate breast reconstruction: a 4-month follow up study
Authors: Kim Asall , Yang Eun Joo , Ji Myungki , Beom Jaewon , Yi Chunghwi 
Published: October 2022

Background
After breast cancer, some patients report residual pain-related upper limb disability without physical impairment. Although pain and altered proprioception are known to affect the working body schema (WBS), there is little available evidence investigating the WBS of breast cancer survivors (BrCS). WBS—body representations in the brain—affect the “neuromatrix” that modulates pain sensitivity and the threshold for threatening stimuli. The aim of this study was to investigate whether WBS was disrupted after mastectomy with immediate breast reconstruction (IBR) for breast cancer and whether pain and proprioceptive changes affected WBS.

Methods
Thirty-five BrCS participated in the 4-month follow-up study. They were observed at 1 and 4 months postoperatively. The main outcome measures were the left right judgement test (LRJT) results, absolute angle error, pectoralis minor length index (PMI), pain, and Quick-Disabilities of the Arm, Shoulder, and Hand (Q-DASH) score. They were measured at each observation, and parametric tests were performed to identify the nature of WBS.

Results
Both the reaction time and accuracy of the hand LRJT were poorer than those of the foot and back LRJT (p < 0.001). The hand LRJT reaction time and accuracy were unchanged over the total follow-up period (p = 0.77 and p = 0.47, respectively). There was a weak correlation between the LRJT reaction time and PMI (r = −0.26, p = 0.07), pain severity (r = 0.37, p = 0.02), and Q-DASH score (r = 0.37, p = 0.02). There was also a weak correlation between LRJT accuracy and Q-DASH score (r = −0.31, p = 0.04). The LRJT accuracy of BrCS who underwent surgery on their dominant side was higher than that of BrCS who underwent surgery on their non-dominant side (p = 0.002). Regression analysis found a weak but significant relationship between the early hand LRJT results and late pain severity (adjusted R2 = 0.179, p = 0.007). A similar relationship was found between early hand LRJT results and Q-DASH score (adjusted R2 = 0.099, p = 0.039).

Conclusion
To the best of our knowledge, this is the first study providing the nature of WBS after mastectomy with IBR. In this population, it is necessary to postoperatively preserve WBS integrity for pain and upper limb disability.
JOB ACCOMPLISHMENT THROUGH INFORMATION TECHNOLOGY COMPETENCIES AND CORPORATE SOCIAL MEDIA USAGE OF COMPANY EMPLOYEES IN INDONESIA
Authors: Mujanah Siti 
Published: October 2022

This research aimed to examine the factors that could affect the distribution of jobs accomplishment, which was included the distribution of corporate social media, information technologies competencies, and jobs interconnections. This research used the partial least square-structural equation model (PLS-SEM) to test the proposed hypothesis. Participants in this study included 367 respondents as the employees in Indonesia. The data collected in this research used a surveyed approached to get responses from participants. The results of data analysis in this research revealed that corporate social media had a significant direct effect on jobs accomplishment and jobs interconnections. In addition, the information technologies competencies had also showed to have an essential direct role in jobs accomplishment and jobs interconnections. Jobs interconnections had also showed to have a significant direct influence on jobs accomplishment. This study proved that jobs interconnections had a significant mediating effect on the relationship between corporate social media and jobs accomplishment, but it had no influencers the relationship between information technologies competencies and jobs accomplishment.
Palladium‐Catalyzed Annulative Allylic Functionalization Reactions
Authors: Ansari Arshad J. , Singh Bara , Ramasastry S. S. V. 
Published: October 2022

Abstract
The development of efficient synthetic methods incorporating novel catalytic paradigms is of significant interest to organic chemists. The recent advancements in catalysis have manifested the tremendous potential of transition metal‐catalyzed processes in advancing organic synthesis to a new height. Especially, palladium‐catalyzed transformations provide simple solutions to several synthetic challenges and generate diverse and complex scaffolds with atom‐, pot‐, and step‐economy. This article discusses the advancements in the “Pd‐catalyzed intramolecular allylic alkylation reactions” during the last 20 years. The chosen examples highlight the relevance of CH functionalization reactions in the total synthesis and underscore their future potential in chemical synthesis.
Pd‐Catalyzed CH Olefination Reactions
Authors: Riente Paola , Jia Wen‐Liang , FernÁndez‐IbÁñez M. Ángeles 
Published: October 2022

Abstract
Alkenes are valuable synthetic intermediates present in natural products, bioactive compounds, and materials. Palladium‐catalyzed CH olefination reactions have become an attractive alternative to the commonly used Pd‐catalyzed Mizoroki–Heck cross‐coupling since no prefunctionalization of the starting materials is required. Major efforts have been devoted to developing selective, efficient, and general palladium‐catalyzed CH olefination reactions employing directing groups and ligands. Nowadays, the toolbox of palladium‐catalyzed CH olefination reactions is enormous, permitting the olefination of a wide range of substrates at different positions. In this article, we will offer an overview of the most important palladium‐catalyzed CH olefination reactions of arenes and alkanes.
Oxidative CH Bond Functionalization Mediated by Organopalladium(II) Complexes with Oxygen as Terminal Oxidant
Authors: Vedernikov Andrei N. 
Published: October 2022

Abstract

A rapidly growing area of oxidative CH bond functionalization reactions utilizing O
2
as terminal oxidant and palladium complexes as catalysts is reviewed. First, the most general mechanisms of the key steps involved in such reactions are briefly considered, (i) CH bond activation at a Pd(II) center and (ii) oxidative functionalization of the resulting Pd(II)C bond. The later step remains the least explored but the growing understanding of the underlying reaction mechanisms can drive the future development of this area of catalysis. In particular, the use of carefully chosen ligands can translate to a significant acceleration of aerobic oxidative CH functionalization reactions. Next, a review is presented of the current scope of the reaction. This section is organized according to the type of CH bond broken, C(sp
3
)H, or C(sp
2
)H, as well as the type of a new CX bond formed (X = O, N, C, B, S) and the functional group installed. In each particular example, a comment is provided on the proposed reaction mechanism.
Palladium‐Pincer Complexes in CH Bond Activation
Authors: Paul Sabarni , Paik Aniruddha , Das Rahul , Rana Sujoy 
Published: October 2022

Abstract
Palladium‐pincer complexes containing monoanionic, tridentate pincer ligand have evolved as a privileged synthetic tool that can be applied in different fields of research including material science and synthetic organic chemistry such as cross‐coupling, hydrophosphination, and allylation reaction. Among them, CH bond activation is one of the most efficient, convenient, and greener approach due to its ability to perform corresponding functionalization from easily available and naturally abundant feedstock. However, number of the reports solely highlighting the application of Pd‐pincer complexes in CH activation is very less. In this article, we have discussed the synthesis of Pd‐pincer complexes via CH bond activation followed by their useful application in the field of CH bond activation.
Rhodium‐Catalyzed CH Functionalization with Photoredox Catalysis
Authors: Liu Ruixing , Wei Yin , Shi Min 
Published: October 2022

Abstract
Rhodium‐catalyzed CH bond activation and visible‐light‐induced photocatalysis are amongst the most rapidly expanding fields in organic chemistry and these approaches display complementary characteristics and applications. Innovative reactions for CH functionalization through combining rhodium catalysis and visible‐light‐induced photocatalysis strategies are reported in recent years. Such synergistic dual catalysis gives a promise of devising previously inaccessible transformations and the synthesis of coupling products, which is difficult to access via a traditional CH activation strategy. Although this approach seems particularly tempting, the reported examples of such protocols remain rarely. Further development in this field is highly demanded.
Ruthenium‐Catalyzed Multiple Functionalization of Arene CH Bonds
Authors: Mukherjee Kallol , Shankar Majji , Sahoo Akhila K. 
Published: October 2022

Abstract
Multiple functionalization of environmentally different C(arene)H bonds with distinct functional groups is synthetically important. This process introduces various functionalities in the molecule, making the easily accessible less‐functionalized compounds to structurally complex molecular scaffolds. Although symmetrical multiple functionalizations of C(arene)H bonds are largely well explored, the unsymmetrical multiple functionalization of C(arene)H bonds is often nonselective, uncontrolled, and unproductive. This article briefly discusses the conceptual growth in ruthenium (Ru)‐catalyzed symmetrical and unsymmetrical multifold functionalizations of C(arene)H bonds, which is exceedingly appealing and highly important.
Electrochemical CH Activation Catalyzed by Cobalt and Copper: Synthetic Strategies and Mechanistic Illustration
Authors: Ghosh Munmun , Mallick Samrat , De Sarkar Suman 
Published: October 2022

Abstract
Transition metal‐catalyzed CH activation has gained immense attention in modern age organic synthesis by means of its widespread applicability associated with the advantages of the atom‐ and step economy, reduced waste generation, and overall sustainability. In order to minimize the use of sacrificial oxidants in the course of transition metal‐catalyzed CH activation, electrosynthesis emerged as a potential greener alternative, thereby providing a viable way toward catalytic activation of CH bonds using electrons as environmental friendly oxidants. In this article, we present a systematic description of electrochemical CH functionalization catalyzed by two cost‐efficient and earth‐abundant 3d transition metals, cobalt, and copper. Besides their other prominent features, the uniqueness of these two metals lies in their versatile modes of action and adaptability to various oxidation states, when used under electrochemical conditions.
CH Arylation of Saturated
N
‐Heterocycles
Authors: Haldar Surajit , Mandal Sumana , Jana Chandan K. 
Published: October 2022

Abstract

Saturated
N
‐heterocycles having an aryl group are core structures of numerous natural products, pharmaceuticals, chiral catalysts, etc. Therefore, different strategies have been developed for the synthesis of arylated
N
‐heterocycles. In contrast to multistep synthesis, the development of direct arylation of saturated
N
‐heterocycles has become increasingly popular in recent years. This article summarizes the methods for the synthesis of arylated
N
‐heterocycles through direct CH arylation of alicyclic amines.
Iron‐Catalyzed Enantioselective CH Functionalization
Authors: Asako Sobi , Ilies Laurean 
Published: October 2022

Abstract
Because of the combined attractive features of iron as a sustainable catalyst and of CH functionalization, over the past several decades the chemistry of iron‐catalyzed CH functionalization has attracted much attention and is growing rapidly. This article briefly introduces the recent emergence of iron‐catalyzed enantioselective CH functionalization reactions that have been achieved by controlling the reactivity and coordination environment of active iron species by chiral ligands.
Nickel‐Catalyzed Benzylic CH Functionalization
Authors: Sharma Dipesh M. , Punji Benudhar 
Published: October 2022

AbstractNickel‐catalyzed CH functionalization has emerged as a powerful tool for the sustainable synthesis of strategic organic molecules. While many efforts have focused on the functionalization of C(sp2)H bond on arenes and heteroarenes in past decades, much less research has been devoted to the activation and functionalization of challenging benzylic C(sp3)H bonds. This article highlights the development in the area of benzylic C(sp3)H functionalization, with a particular emphasis on reaction development, scope, and reaction mechanism.
CH Functionalization Methods in Flow Conditions
Authors: Ferlin Francesco , Carpisassi Luigi , Brufani Giulia , Vaccaro Luigi 
Published: October 2022

Abstract
This article will discuss the adoption of flow conditions in CH functionalization processes highlighting the possible benefits in terms of reactivity, reaction time, and/or safety of the procedure and where possible, results obtained in flow will be compared to those in batch conditions. Main features of the reactor systems will be discussed and the use of tailor‐made customized or commercially available flow system will be compared. Most recent key examples utilizing flow systems in CH functionalization reactions will be discussed including the most relevant report present in the literature until July 2021.
Understanding Methane Activation at Pt Centers from the Perspective of Microscopic Reversibility
Authors: Pal Shrinwantu 
Published: October 2022

Abstract

Despite 50 years since Shilov's seminal discovery, till date no practical systems for catalytic methane functionalization, one of the grandest challenges of chemistry, exist. Approaches to tackle this can be segregated into two, but often overlapping, themes –
synthetic efforts
focusing on the development of new metal–ligand platforms and
mechanistic efforts
focusing on step‐wise delineation of the intended catalytic cycle. This article discusses the mechanism of methane activation from the perspective of microscopic reversibility as inferred through kinetic isotope effects and observation of isotope scrambling.