bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluating the quality of life among melasma patients using the MELASQoL scale: A systematic review and meta-analysis
Authors: Zhu Yuan , Zeng Xiaofang , Ying Jieya , Cai Yujia , Qiu Yu , Xiang Wenzhong 
Published: January 2022

BackgroundAccording to the literature, pigmentary disorders have a significantly negative impact on a person’s health-related quality of life. Moreover, among pigmentary disorders, incidence of melasma ranks high. The Melasma Area and Severity Index (MASI) is the scale that is generally used to evaluate a melasma-affected area and its severity. However, the relationship between the MASI and Melasma Quality of Life (MELASQoL) scores, as well as the impact of melasma on patients’ quality of life, remain unclear.ObjectivesTo explore the influence of melasma on patients’ lives, analyze the relationship between the MASI and MELASQoL scores, and identify the factors that may be influencing the quality of life of patients with melasma.MethodsTwo reviewers independently searched four databases (PubMed, Embase, the Cochrane Library, and Web of Science) for literature on quality of life of patients with melasma. In addition to an epidemiological study, a cross-sectional study, and validation studies, gray literature was also included. StataSE version 16 software was used for the meta-analysis. The score of each item on the MELASQoL scale was determined using a random-effects model.ResultsFourteen studies with a total of 1398 melasma patients were included in the systematic review, four of which were eligible for meta-analysis. The relationship between the MELASQoL and MASI scores was found to be mixed. Five studies concluded that the MASI and MELASQoL scores were statistically correlated, while seven studies found no statistical correlation between the two. It is obvious that melasma causes emotional distress and has a negative impact on patients’ social lives. Patients were most bothered by the appearance of their skin condition. However, the MELASQoL score had no definite correlation with patient characteristics such as age, education levels, and history.ConclusionMelasma has a significant negative impact on patients’ quality of life. Thus, evaluating the quality of life of patients with melasma should not be ignored. Additionally, utilization of the MELASQoL scale should be considered in the care plan. Further studies with larger sample sizes are needed to confirm the relationship between melasma and quality of life.
Social cognitive outcomes are associated with improvements in mobility performance following lifestyle intervention in prostate cancer patients undergoing androgen deprivation therapy
Authors: Chaplow Zachary L. , Lucas Alexander R. , Grainger Elizabeth , Simpson Christina , Fairman Ciaran M. , DeScenza Victoria R. , Bowman Jessica , Clinton Steven K. , Focht Brian C. 
Published: January 2022

ObjectiveTo compare the effects of an exercise and dietary intervention with those of standard-of-care management upon change in lift and carry performance and mobility-related self-efficacy beliefs and explore associations in prostate cancer patients undergoing androgen deprivation therapy.Methods32 prostate cancer patients (Mage = 66.2 years;SD= 7.8) undergoing androgen deprivation therapy were randomly assigned to a 3-month exercise and dietary lifestyle intervention (n= 16) or standard-of-care management (n= 16). Outcome assessments were obtained at baseline, 2- and 3-month follow-up.ResultsThe lifestyle intervention resulted in significantly greater improvements in lift and carry performance (p= 0.01) at 2 Months (d= 1.01; p < 0.01) and 3 Months (d= 0.95; p < 0.01) and superior improvements in mobility-related self-efficacy at 2 Months (d= 0.38) and 3 Months (d= 0.58) relative to standard-of-care. Mobility-related self-efficacy (r= -.66;p= 0.006) and satisfaction with function (r= -.63;p= 0.01) were significantly correlated with lift and carry performance at 3 Months.ConclusionsThe exercise and dietary lifestyle intervention yielded superior improvements in lift and carry performance and mobility-related self-efficacy relative to standard-of-care and key social cognitive outcomes were associated with more favorable mobility performance.
Association between the caregivers’ oral health literacy and the oral health of children and youth with special health care needs
Authors: Baskaradoss Jagan Kumar , AlSumait Aishah , Behbehani Eman , Qudeimat Muawia A. 
Published: January 2022

Aim
Previous studies have shown that children of caregivers with low oral health literacy (OHL) had more untreated caries than children of caregivers with adequate OHL. However, there is a paucity of information on this relationship among children and youth with special health care needs (CYSHCN). Accordingly, this study aims to assess the association between the caregivers’ OHL and the oral health status of CYSHCN.

Methods
This cross-sectional study was conducted in four schools dedicated for CYSHCN. A 48-item questionnaire gathered information about the demographic and socioeconomic factors, the child/adolescent’s medical condition, dental characteristics, caregiver self-efficacy and the child’s dental attitude. The Comprehensive Measure of Oral Health Knowledge (CMOHK) questionnaire was used to assess the caregivers’ OHL. The Löe & Silness gingival index (GI) and the Silness & Löe plaque index (PI) were used to assess gingival health and plaque levels, respectively. Directed acyclic graphs (DAGs) were utilized for the selection of the appropriate set of confounding variables for regression analysis. The mean score differences and 95% confidence intervals (CI) were estimated to quantify the associations of the various covariates with oral health outcome variables.

Results
This study included 214 child/caregiver dyads. Most participants were physically disabled (56.1%) followed by children with hearing difficulty (9.8%) and congenital anomalies/syndromes (7.9%). The mean PI and GI of the children was 1.26±0.52 and 1.30±0.47, respectively. The median CMOHK score was 12 and the respondents were dichotomized based on the median value. Low caregiver oral health conceptual knowledge was significantly associated with higher PI scores (β [95% CI] = -0.26 [-0.41, -0.13]; p<0.001. Older participants (12-21-year-olds) had significantly higher plaque scores compared with younger participants (6-12-year-olds) (β [95% CI] = 0.33 [0.18, 0.51]; p<0.001). Participants who brushed their teeth twice or more daily had significantly lower (β [95% CI] = -0.15 [-0.43, -0.01]; p = 0.046). Conceptual knowledge score was not significantly associated with GI.

Conclusion
This study found lower caregiver OHL levels to be associated with higher plaque scores for their child.
La demarcación de los espacios de tránsito en Los Millares (Santa Fe de Mondújar, Almería) y su relación con el simbolismo megalítico
Authors: Cámara Serrano Juan Antonio , Dorado Alejos Alberto , Spanedda Liliana , Fernández Ruiz Marcos , Martínez García Julián , Haro Navarro Martín , Martínez Fernández Gabriel , Carrión Méndez Francisco , Molina González Fernando 
Published: January 2022

Recientes investigaciones en el yacimiento calcolítico de Los Millares, Santa Fe de Mondújar, Almería, han permitido reconocer diferentes representaciones figurativas asociadas a la muralla más exterior o Muralla I, construida en torno a 2900 cal AC. La erección de esta muralla supuso una importante ampliación del poblado al ocupar zonas anteriormente destinadas a necrópolis. Se propone que algunos elementos pertenecientes al área de necrópolis fueron respetados y reutilizados para justificar, a través de los ancestros, la capacidad de acceder al asentamiento a través de la puerta principal –con la estatua-menhir situada junto a esta–, la exclusión de aquellos no vinculados –con todas las representaciones en ambos extremos de la muralla–, la integración de nuevas poblaciones –con la Tumba 63 incluida en el trazado de la muralla–, el rol de determinados personajes –con la estatua-menhir y la estela de la Tumba 63– y, en definitiva, los derechos a ocupar y explotar un territorio. Se señala además la relación de estos procesos con los identificados tradicionalmente en las tumbas de la necrópolis.
A adição com números naturais em materiais de apoio para professores primários paulistas (1981–1988)
Authors: Silva Angelica da Fontoura Garcia , Duarte Aparecida Rodrigues Silva , Silva Valdir Amâncio da 
Published: January 2022

Este artigo examina como a adição com números naturais para a primeira série do Ciclo Básico do Ensino Fundamental está proposta no material de apoio ao currículo intitulado Atividades Matemáticas, publicado em 1981 e na Proposta Curricular para o Ensino de Matemática, 1º Grau do Estado de São Paulo de 1988, com o propósito de identificar elementos de aproximações e distanciamentos sobre o ensino da adição presentes nesses manuais. Foi possível constatar que, embora com finalidades diferentes, notam-se pontos comuns nessas obras, em especial, a sugestão para que o professor oferecesse condições para que os alunos pudessem vivenciar situações que permitissem a compreensão e memorização dos procedimentos de cálculo por meio de materiais manipuláveis, incorporando experiências do cotidiano dos alunos antes da formalização. As reflexões aqui apresentadas podem representar uma base de trabalho para prosseguimento de estudos relativos às orientações didático-metodológicas sobre o ensino das outras operações com números naturais presentes nestes documentos.
Educação municipal e a escola em tempo integral
Authors: Neto Alfredo Alcure , Nossa Silvania Neris , Teixeira Aridelmo , Moreira Nadia Cardoso 
Published: January 2022

O estudo se propôs verificar a associação entre I-Educ, indicador que compõe uma das dimensões do IEGM, com indicadores que acompanham o aprendizado dos alunos e as matrículas em tempo integral. Adotou-se como período de análise os anos de 2015 e 2017 nos municípios dos Estados brasileiros, totalizando 7.852 observações. Metodologicamente, foi proposto um modelo no qual o I-Educ atua como variável dependente, e a Prova Brasil, TRM, ETI e IRD como variáveis independentes, foram utilizados testes estatísticos para estimar a relação estudada, inclusive foi utilizada a análise de regressão probit e efeito marginal. Os resultados mostram uma relação positiva e significativa entre o I-Educ e as variáveis independentes Prova Brasil, TRM e ETI, não alcançando significância com o IRD. Este estudo avançou na literatura em direção à validação de um modelo de acompanhamento da política pública educacional municipal com foco no impacto gerado das ações de governo, auxiliando no monitoramento da política pública educacional. A contribuição prática desta pesquisa está em conferir aos Tribunais de Contas, gestores públicos e sociedade civil, embasamento estatístico da capacidade do I-Educ em avaliar a efetividade dos atos de gestão educacional, demonstrando que os quesitos aplicados, decorrente do monitoramento de infraestrutura e práticas administrativas, possibilitam o acompanhamento do aprendizado do aluno da rede pública municipal.
A magia da realidade: mitos, ficção e ciência
Authors: Santos José Douglas Alves dos 
Published: January 2022

Resenha de:
DAWKINS, Richard. A magia da realidade: como sabemos o que é verdade. Ilustrações de Dave McKean. Tradução de Laura Teixeira Motta. São Paulo: Companhia das Letras, 2012.
Portrait of Regional Trends in Liver Transplantation for Nonalcoholic Steatohepatitis in the United States
Authors: Yuan Liyun , Hanlon Courtney L. , Terrault Norah , Alqahtani Saleh , Tamim Hani , Lai Michelle , Saberi Behnam 
Published: January 2022

INTRODUCTION:
Nonalcoholic steatohepatitis (NASH) is one of the most common etiologies of liver transplantation (LT) in the United States. We investigated regional trends in waitlist candidates, LT rates, and recipient survival among patients with NASH.

METHODS:
Using the United Network for Organ Sharing database by Organ Procurement and Transplantation Network regions, we investigated waitlist registration, LT rates, and survival for NASH between January 2004 and December 2019.

RESULTS:
The absolute number and percentage of total LT performed for NASH increased substantially in all Organ Procurement and Transplantation Network regions. In 2019, region 11 had the highest percentage of NASH-related LT with 31.4% followed by region 10 (25.3%) and region 8 (23.1%). Between 2015 and 2019, region 5 had the highest rising percentage in LT for NASH at 208%, followed by region 1 (194%) and region 4 (183%). The proportion of NASH hepatocellular carcinoma (NASH-HCC) was the highest in region 9 at 37.7% and lowest in region 10 (19.2%), region 3 (20.6%), and region 11 (20.8%). In multivariate analysis, diabetes (HR 1.18, P < 0.001), dialysis before LT (hazard ratio [HR] 1.53, P < 0.001), HCC (HR 1.19, P < 0.00), portal vein thrombosis (HR 1.24, P < 0.001), donor age (HR 1.026, P = 0.03), and recipient age (HR 1.24, P = <0.001) were associated with worse survival.

DISCUSSION:
LT for patients with NASH has dramatically increased across all regions since 2004, but with substantial heterogeneity among regions in the proportion with HCC and post-LT survival. Identifying contributing factors to these regional differences is warranted.
Floodplain wetlands of eastern India in a changing climate: Trophic characterization, ecological status, and implications for fisheries
Authors: Puthiyottil M. , Sarkar U.K. , Lianthuamluaia L. , Karnatak G. , Hassan M.A. , Kumari S. , Ghosh B.D. , Das B.K. 
Published: January 2022

AbstractIndia is endowed with vast floodplain wetland resources (0.5 million ha), which provide both livelihood and nutritional security to much of the rural populace. These biologically sensitive ecosystems are threatened by a range of anthropogenic and climatic factors. Assessment of their ecological vulnerability, and of the environmental threats that they face, is essential both in evaluating the health of these ecosystems and in developing sustainable management strategies for conservation and fisheries enhancement. In this context, eight wetlands in the Ganga basin were studied for two consecutive years across the seasons and were characterized ecologically based on chlorophyll a, primary productivity, and trophic state index. A warming temperature (+0.20 – +0.47 °C) and a decreasing total annual rainfall (257–580 mm) have been observed along the Ganga basin in the last three decades. The chlorophyll a (mean ± S.E.) content of the water varied from 4.08 ± 1.04 to 38.0 ± 14.11 µg l-1. The high primary productivity, gross primary productivity/plankton respiration ratio and trophic state index correlated positively with the high fish yield in the wetlands. Analysis of data based on Carlson's method revealed five wetlands in the eutrophic category, whereas based on Lamparelli's method, two wetlands fall into the eutrophic category. The Lamparelli TSI value ranged from 54.1 in Majharia to 65.8 in Kararia among the wetlands. The Bishnupur wetland in West Bengal and Kararia wetland in Bihar were found to be eutrophic due to cascading sewage incursion from nearby towns. These altered ecosystems with high TSI values were prudently exploited by selecting suitable fish species for high fish production, and a fish yield of 1200 kg ha-1 yr-1 was achieved in Bishnupur. The study revealed that eutrophic wetlands can be strategically managed for maintaining both ecosystem services and fish production. Careful selection of suitable fish species and stocking rate is crucial. The planned disposal and treatment of sewage is recommended to maintain the ecological health of floodplain wetlands for sustainable fisheries management in the context of a changing climate.
Enhancing adaptive capacity of wetland fishers through pen culture in the face of changing climate: A study from a tropical wetland, India
Authors: Karnatak Gunjan , Sarkar Uttam Kumar , Puthiyottil Mishal , Lianthuamluaia Lianthuamluaia , Ghosh Bandana Das , Bakshi Snigdha , Das Archan Kanti , Das Basanta Kumar 
Published: January 2022

Abstract
Wetlands are among the most productive of all aquatic ecosystems. In developing countries, millions of marginal fishers rely solely on wetlands for security of both nutrition and livelihood. The decline in wetland fisheries owing to anthropogenic and climatic changes has made fishers increasingly vulnerable. Pen culture can be an effective climate-resilient technology for enhancing fish production in shallow, macrophyte-choked, and multi-stake floodplain wetlands, especially in eastern and north-eastern India. In this context, pen culture was implemented as an adaptive measure in a tropical Gangetic wetland (Mathura) to enhance fish production and increase the adaptive capacity of fishers. Indian Major Carps, Gibelion catla, Labeo rohita, and Cirrhinus mrigala of initial size 10.4±.21g, 8.2 ± 0.48g, and 6.5 ± 0.23g respectively, were stocked at the ratio of 4:4:2 and at the rate of 30 fish m-2 each in pens of 100 m2 in duplicate. For purposes of conservation, Labeo bata and Gudusia chapra, 4.3 ± 0.18g and 3.8±.34g initial size, respectively, were stocked at the rate of 20 Nos.m-2 each at the ratio of 1:1. The fish were fed with commercial feed at the rate of 4% of body weight. A net survival of 82%, 87%, and 75% was recorded in Indian Major Carps, L. bata and G. chapra. A production of 380 kg IMC was achieved during 120 days of the culture period. L. bata achieved an average weight of 21.40 ± 0.34g during the 90-day culture period, with a survival rate of 87%. G. chapra attained an average weight of 16.5 ± 0.42g during the culture period, with a recorded survival rate of 75%. G. chapra was observed to spawn in the pen. The water quality inside pens and reference sites did not differ significantly (p &gt;0.05). The produced fish were released in the wetland for fisheries enhancement. The present communication discusses the technological suitability and economic feasibility of adopting climate-resilient pen culture as an adaptation measure for enhancing the adaptive capacity of wetland fishers in the face of a changing climate.
SIW-based dual-beam conical conformal slot array antenna for X-band applications
Authors: Khalil Hisham , Rafique Umair , Ahmed M. Mansoor 
Published: January 2022

AbstractA design of substrate integrated waveguide (SIW) based conical conformal slot array antenna is presented for X-band applications. The proposed design consists of two SIW arrays of 1 × 6 slot radiators located atϕ = 0° andϕ = 180°. The slotted arrays are fed using a rectangular waveguide (RWG) to SIW 1 × 2 T-junction power divider. The arrays are projected in the longitudinal direction on a conical surface having a lower and upper radius of 1.66λ0and 1.33λ0, respectively. The power divider and SIW arrays are designed and simulated in full-wave EM simulation software. It is observed from the results that the proposed array has two main beams in the H-plane located atθ = ±${\pm}$90°, and have sidelobe levels (SLLs) of −23 dB and −20 dB, respectively. For the validation of simulation results, the proposed array is fabricated and measured, and a reasonable agreement is observed between both results.
The weak eigenfunctions of boundary-value problem with symmetric discontinuities
Authors: Olğar Hayati , Mukhtarov Oktay S. , Muhtarov Fahreddin S. , Aydemir Kadriye 
Published: January 2022

Abstract
The main goal of this
study is the investigation of discontinuous boundary-value problems
for second-order differential operators with symmetric transmission
conditions. We introduce the new notion of weak functions for such
type of discontinuous boundary-value problems and develop an
operator-theoretic method for the investigation of the spectrum and
completeness property of the weak eigenfunction systems.
In particular, we define some self-adjoint compact operators in
suitable Sobolev spaces such that the considered problem can be
reduced to an operator-pencil equation. The main result of this
paper is that the spectrum is discrete and the set of eigenfunctions
forms a Riesz basis of the suitable Hilbert space.
Geometric quality control for bio-based building elements: Study case segmented experimental shell
Authors: Kerekes Gabriel , Petrš Jan , Schwieger Volker , Dahy Hanaa 
Published: January 2022

Abstract
This contribution presents the prerequisites in the construction process of a bio-based experimental pavilion. A first challenge, is to define tolerances and implicitly measurement tolerances for these materials. After defining them, the focus is set on what can be achieved if geometric quality control is only conducted during the assembly process. Despite using high-end total stations and terrestrial laser scanners in this process, the final pavilion showed discrepancies to its model. In some cases, these were larger than the given tolerances, showing on one side what tasks can be achieved with these instruments and on the other, drawbacks that remain a challenge in bio-based segmented experimental buildings. Finally, an improved workflow is suggested.
Evaluation of patients with phenylalanine metabolism disorder: a single center experience
Authors: Erdol Sahin , Bilgin Huseyin 
Published: January 2022

AbstractAimThe aim is to evaluate the clinical, demographic and laboratory data of the patients we followed up with phenylalanine metabolism disorder.Materials and methodsIn this study, patients with phenylalanine metabolism disorder who applied to Bursa Uludag University Faculty of Medicine, Department of Pediatrics, Pediatric Metabolism Department between 2011 and 2021 were retrospectively examined. The files of 397 patients who were followed up in our pediatric metabolism outpatient clinic and were found to have phenylalanine metabolism disorder by plasma phenylalanine level and molecular genetic analysis were evaluated.ResultsAccording to the highest plasma phenylalanine levels at admission, mild hyperphenylalaninemia phenotype constituted the largest group of 397 patients with 282 cases (71.1%), while the least common phenotype was malignant phenylketonuria (BH4 metabolism disorder) with four patients (1.0%). The number of patients with classical phenylketonuria was 90 (22.6%). 61 (62.8%) of 97 phenylalanine metabolism disorder cases who underwent BH4 loading test had a response. The mean phenylalanine level of the patients was 3.62 ± 1.31 mg/dL in mild hyperphenylalaninemia, 7.98 ± 3.99 mg/dL in mild phenylketonuria and 11.71 ± 4.39 mg/dL in classical phenylketonuria. While 241 (76%) of 317 patients younger than 8 years old were in the well-controlled group, 76 (24%) were in the poorly-controlled group. While 41 (53.9%) of 76 patients older than 8 years of age were in the well-controlled group, 35 (46.1%) were in the poorly-controlled group.ConclusionsIn our study, the largest patient group consisted of patients with mild hyperphenylalaninemia, and the least common phenotype was mild phenylketonuria.
Preparation of O-HACC/HEC-acrylate emulsion and its application in paper protection
Authors: Yang Hanhan , Zhang Jinjie , Qi Yingping , Shen Yongfeng , Li Hua 
Published: January 2022

Abstract
To enhance the strength of paper cultural relics and prolong the life of paper cultural relics, it is an urgent need to prepare new material for preservation and protection of paper. In this paper, chitosan quaternary ammonium salt/HEC-acrylate was synthesized with O-hydroxypropyl trimethyl quaternary ammonium salt chitosan (O-HACC) and Hydroxyethyl Cellulose (HEC)-acrylate emulsion, the synthesized materials has multiple functions, such as deacidification, reinforcement, anti-mildew and antibacterial etc. The synthesized new materials were applied on paper, and their protective effect was evaluated by testing the mechanical and optical properties and antibacterial properties of the paper. The results showed that when the mass concentration of O-HACC was 0.6 %, the tensile strength, folding times and tearing strength of the paper coated with protective solution were improved to a certain extent, while the optical properties and appearance of the paper remained basically unchanged. Meanwhile, the paper also had certain anti-mildew and bacterial resistance.