bluuebunny/crossref_metadata_2025_split huggingface dataset:
Amino Acid Metabolism in Gilthead Seabream Is Affected by the Dietary Protein to Energy Ratios
Authors: Teodósio Rita , Aragão Cláudia , Conceição Luís E. C. , Dias Jorge , Engrola Sofia 
Published: May 2022

The dietary protein to energy ratio (P/E) has proven to influence protein utilization and/or growth in several fish species. This study intended to unravel the bioavailability and metabolic fate of lysine and methionine in gilthead seabream (Sparus aurata) juveniles fed plant diets with different P/E ratios. Seabream juveniles were fed two isonitrogenous diets (45% crude protein) differing in crude lipids (20 and 14%): LowP/E (

P
/
E

ratio
=
20.0

mg

protein

k

J

−
1

) and HighP/E (

P
/
E

ratio
=
21.4

mg

protein

k

J

−
1

). After three weeks, fish (

11.6
±
4.3

g

) were tube-fed the respective diet labelled with 14C-protein (L-amino acid mixture), 14C-lysine, or 14C-methionine. Protein, lysine, and methionine utilization were determined based on the proportion of 14C-amino acid evacuated, retained in the free or protein-bound fraction of liver and muscle, or catabolized. This study revealed that a decrease in P/E ratio resulted in lower amino acid evacuation (p <0.05), contributing to a more efficient amino acid uptake. Results indicate that amino acids are retained as protein in the liver and not only temporarily available in the free pool. The amount of free amino acids retained in the muscle of LowP/E fed fish was significantly higher than in HighP/E fish (

p
<
0.05

) due to a simultaneous higher retention of lysine and methionine, without affecting the overall protein retention. Methionine catabolism was significantly lower than lysine or protein independently of the P/E ratio (

p
<
0.05

), reinforcing that this amino acid is preferentially spared for metabolic functions and not used as energy source. In contrast, increasing the dietary P/E ratio decreased lysine catabolism and increased its availability for growth. The bioavailability and metabolism of individual amino acids should be considered when optimizing P/E ratios in diets for gilthead seabream juveniles. Formulating diets with optimum P/E ratios will improve diet utilization and fish performance.
Investigation of displacement ventilation performance under various room configurations using computational fluid dynamics simulation
Authors: Askari Ahmad , Mahdavinejad Mohammadjavad , Ansari Mojtaba 
Published: May 2022

The performance of a ventilation system affects air quality, thermal comfort, and energy consumption in indoor environments. To evaluate the performance of displacement ventilation under various room configurations, steady Reynolds Averaged Navier–Stokes (RANS) Computational Fluid Dynamics (CFD) simulations were used. The CFD model was validated using measurements of a full-scale test room. The age of air concept was used to evaluate the ventilation performance regarding indoor air quality. The PD index was used to control the case studies for draft risk. Twelve cases with different configurations were systematically studied and compared with the reference case. The configurations included plan aspect ratio, exhaust opening position, inlet position and geometry, and internal heat gains. The results showed that the overall ventilation performance of a room is less sensitive to room configurations compared with local ventilation performance around the occupants. However, almost in all cases, the occupants were exposed to better-than-average air quality in most cases. The results also indicated that when internal heat gains are small, displacement ventilation should be used with caution. Practical application: Any HVAC system design is based on assumptions made for ventilation performance. Comprehensive knowledge of the influential factors is critical for an efficient design. Regarding the architecture and interior design, the architects are also involved in the ventilation systems since they have an axial role in decision making for room configuration, including but not limited to room geometry, the position of inlet and outlet air terminals, and heat/pollutant sources. Consequently, the impact of room configuration on ventilation performance is of practical importance in the architecture, engineering, and construction industry.
Trends in Author-Reported Cost-Effectiveness Thresholds in the United States from 1995 to 2018: Implications for Discount Rates
Authors: Pandya Ankur , Paulden Mike , Zhu Jinyi , Lavelle Tara A. , Hammitt James 
Published: May 2022

Background Decisions based on cost-effectiveness analyses (CEAs) using equal discount rates for health and cost outcomes are consistent with using a constant cost-effectiveness threshold over time. We sought to analyze trends in author-reported cost per quality-adjusted life-year (QALY) thresholds from CEAs published for the US setting over 24 y to retrospectively assess whether the recommended equal discount rates for costs and health were consistent with trends in the CEA literature. Methods We used the Tufts CEA Registry to assess whether author-reported cost-effectiveness thresholds changed in CEAs published for the US setting between 1995 and 2018 and back-calculated the implied discount rate for health based on these trends for inflation-adjusted cost-effectiveness thresholds and an annual discount rate for costs of 3%. Results We found 1995 CEAs published for the US setting and found that average nominal and inflation-adjusted cost-effectiveness thresholds increased over that time period. The discount rate for health would need to equal 2.43% to 2.48% (depending on the subset of CEAs analyzed) to be consistent with the observed trends in inflation-adjusted author-reported cost-effectiveness thresholds. We also found that restricting our analysis to currency years between 1995 and 2014 would result in a back-calculated discount rate for health of 2.99% to 3.28%. Conclusions We found that CEA researchers have implicitly assumed that inflation-adjusted cost-effectiveness thresholds in the United States have been increasing over time (1995–2018), which is inconsistent with the recommended and prevailing choice of equal discount rates for health and cost outcomes. Our results are sensitive to the cutoff year used in the analysis. Highlights We show visually and through equations that the recommended and prevailing practice of using equal discount rates for cost and health outcomes in cost-effectiveness analyses (CEAs) logically implies a constant inflation-adjusted cost-effectiveness threshold over time. Using data from the Tufts CEA Registry, we found that author-reported cost-effectiveness thresholds used in CEAs published for the US setting with currency years between 1995 and 2018 increased over time (both with and without adjustment for inflation). Assuming an annual discount rate for costs equal to 3%, the discount rate for health would need to equal approximately 2.5% to preserve consistency across decisions taken at different dates given the observed trends in inflation-adjusted author-reported cost-effectiveness thresholds. This finding depends on the cutoff year used in the analysis (data from currency years 1995–2014 would support use of equal discount rates, whereas data after 2014 would suggest a sharper trend toward increasing cost-effectiveness thresholds).
Parent-Child Concordance and Discordance in Family Violence Reporting: A Descriptive Analysis from the Adolescent Brain Cognitive Development Study®
Authors: Hogan Jasara N. , Garcia Alexis M. , Tomko Rachel L. , Squeglia Lindsay M. , Flanagan Julianne C. 
Published: May 2022

Childhood trauma exposure, including witnessing or experiencing family violence, is associated with a variety of poor outcomes such as increased likelihood of psychopathology and high-risk behaviors across the lifespan. Early treatment may help to buffer these effects, but parents and youth display only moderate levels of agreement in reporting family violence, making it more difficult to identify children who have been exposed. Additionally, most studies on family violence reporting have focused primarily on small samples in specific high-risk populations, and little is known about the generalizability of these findings. Thus, the present study assessed concordance in family violence reporting and its correlates using the population-based, demographically diverse sample from the U.S. Adolescent Brain Cognitive Development (ABCD®) study. Participants were 10,532 children between 9 and 10 years old, and their parent or guardian, from 21 sites across the United States. Overall, 30% ( N = 3119) of the sample reported family violence and most of those reports ( N = 2629) had discordant violence reporting, meaning child- and parent-report did not correspond with each other. Multinomial logistic regression was used to assess the likelihood of participants belonging in one of the following groups: no violence reported, concordant violence reported, and discordant violence reported. Results indicated that Black or Non-Hispanic children, male children, and children with greater externalizing problems were more likely to report family violence, and parents with lower levels of education and income were more likely to report family violence. These findings likely reflect differences in distribution of risk factors among racial and ethnic minoritized individuals including increased parenting stress and decreased access to mental health treatment. Among those reporting violence, Hispanic children and children with less externalizing problems were more likely to be in the discordant group. Findings suggest that both parent and child reports are needed to assess violence and screen for appropriate services.
Development and characterization of surface functionalized hierarchical carbon fiber reinforced hybrid polypropylene composites
Authors: Gogoi Rupam , Manik Gaurav 
Published: May 2022

Light-weight hybrid composites of relevant industrial applications were prepared using surface functionalized hierarchical carbon fibers ( f-CF), silane treated hollow glass microspheres (HGM), and a blend of polypropylene (PP) and maleic anhydride-grafted-styrene ethylene butylene styrene as the base polymer matrix. The f-CF were prepared by coating amine functionalized carbon nanotubes onto silane treated CF using an ultrasonic assisted electrophoretic deposition technique to improve fiber-matrix interfacial adhesion. For hybrid composition of 20 wt.% f-CF and 10 wt.% HGM, the tensile strength and modulus improved by ∼141 and ∼536% over neat PP while flexural strength and modulus increased by ∼118% and ∼583% respectively. Impact strength of 11.06 kJ/m2 was obtained and uniform dispersion and distribution of f-CF and HGMs was observed in Scanning electron microscope (SEM) images. Desirable reduction in density and melt viscosity along with improvement in composite stiffness were observed due to addition of HGM filler. Compared to PP, the crystallization temperature increased by ∼12°C while a maximum decrease of ∼5°C in melting temperature was obtained for the hybrid composites. Crystallinity of the hybrid composites decreased with an evident β crystal formation brought in by the nucleation.
Influence of micro-sized Al2O3 particles on microstructure, mechanical, and wear behavior of dissimilar composite joint of AA6061/AA7075 by friction stirprocessing/welding
Authors: Jain Sumit , Mishra RS 
Published: May 2022

In the present study, the fabrication of dissimilar composite joints of AA6061/AA7075 incorporated with micro-sized Al2O3 particles was carried out using friction stir welding. The impact of the dispersion pattern of different volume fractions of Al2O3 micro-particles (Al2O3mp) under various combinations of tool rotational speed (RS) and traverse speed (TS) on the weld quality was studied. The composite joints were tested for tensile strength, micro-hardness, wear, and microstructural development. The results demonstrated that higher grain refinement due to dynamic recrystallization (DRX) and pinning effect of Al2O3mp considerably improved the weld quality. Higher improvements in the mechanical properties of the composite joints were also observed as the volume fraction of Al2O3mp increased. Consequently, the composite joint processed at RS of 1100 rpm, TS of 40 mm/min with 10% volume fraction of Al2O3mp exhibits the higher tensile strength of 241.35 MPa with joint efficiency of 83.80% and maximum micro-hardness of 157.5 HV. In comparison with base materials, the incorporation of Al2O3mp also improved the wear resistance of the composite joints.
Effect of the hub cavity leakage on the aerodynamic performance and strength characteristics of the 150 kW SCO2 centrifugal compressor
Authors: Cao Run , Li Zhigang , Deng Qingua , Li Jun , Gao Tieyu 
Published: May 2022

The hub cavity leakage has large effect on the aerodynamic performance on the Supercritical carbon dioxide (SCO2) centrifugal compressor. In this paper, the aerodynamic performance and strength characteristics of the 150 kW SCO2 centrifugal compressor with the hub cavity were numerically investigated using three-dimensional Reynolds-Averaged Navier-Stokes (RANS) and [Formula: see text] turbulence model. The high precision physical properties tables of SCO2 were used to calculate the SCO2 property parameters across the centrifugal compressor flow passages. The aerodynamic performance of the 150 kW SCO2 centrifugal compressor without and with the hub cavity and the labyrinth seal at different mass flow coefficients was compared. The equivalent (von-Mises) stress and the deformation on the SCO2 centrifugal impeller were obtained by the combination of the aerodynamic pressure and centrifugal force calculation. The results show that the isentropic efficiency of the SCO2 centrifugal compressor without and with the hub cavity and the labyrinth seal at the designed flow coefficient equal 73.2% and 72.1% respectively. The effects of the hub cavity leakage on the pressure ratio of the SCO2 centrifugal compressor are limited. The hub cavity leakage decreases with the flow coefficient increasing. The similar isentropic efficiency of the SCO2 centrifugal compressor without and with the hub cavity and the labyrinth seal at the largest flow coefficient is obtained. The axial thrust of the SCO2 centrifugal compressor with the hub cavity and the labyrinth seal ranges from 1000N to 2000N at different flow coefficients, as well as keeps the same direction. The maximum equivalent (von-Mises) stress of the impeller is 109.95 MPa and less than the allowable stress 137 MPa (using 304 steel as the impeller material). The maximum deformation of the seal teeth is less than 0.003 mm. This work provides the reference of the compressor design and safety operation for the SCO2 centrifugal compressor.
Point of view: Could social media use be contributing to rising rates of deliberate self-harm and suicide in Australian youth populations?
Authors: Webb Beatrice , Looi Jeffrey CL , Allison Stephen , Bidargaddi Niranjan , Bastiampillai Tarun 
Published: May 2022

Objective A rapid clinical update on the potential interplay between social media use and rates of deliberate self-harm amongst young people in Australia. Conclusions Rising social media use has been associated with increasing cyberbullying and deliberate self-harm, especially in young women. On the other hand, social media use also provides beneficial support. Examination of problematic social media use in assessments of young people presenting with self-harm may be useful, along with discussion of responses to negative social media. In this point of view, we discuss these matters and the UK Royal College of Psychiatrists’ recommendations for reducing the negative impact of social media.
The Long-Run Effects of Communism and Transition to a Market System on Self-Employment: The Case of Germany
Authors: Fritsch Michael , Greve Maria , Wyrwich Michael 
Published: May 2022

We investigate how self-employment in East Germany was impacted by 40 years of Soviet-style communism and the subsequent shock transition to a market economic system. To this end, we compare self-employment in East and West Germany after reunification with self-employment before the separation of Germany after World War II. Our results show that the strict anti-entrepreneurial policies prevalent during the Soviet regime do not have a long-run negative effect on self-employment in East Germany. Quite to the contrary, self-employment in East Germany today is higher than before German separation. This finding cannot be explained by necessity self-employment. Our analysis suggests that current differences in self-employment between East and West Germany are pre-dominantly a result of the sudden shock transformation that occurred with reunification, rather than the outcome of four decades of anti-entrepreneurial policies and ideology.
Coping Skills Interventions for Fatigue in Adults with Hematologic Malignancies: A Systematic Review
Authors: Andersen Lucy , McHugh Molly , Ulrich Connie , Meghani Salimah , Deng Jie 
Published: May 2022

Background: Persons with hematologic malignancies have a high symptom burden throughout the illness journey. Coping skills interventions effectively reduce fatigue for other cancer patients. The purpose of this systematic review is to identify if coping interventions can reduce fatigue in patients with hematologic malignancies. Methods: A search of PubMed, Embase, CINAHL, APA Psych INFO, Scopus, Cochrane, and non-traditional publications was performed in June 2021 for studies introducing coping interventions for adults with hematological cancers within the past 20 years. The Transactional Model of Stress and Coping was used as a framework with fatigue as the primary outcome. The Johns Hopkins Nursing Evidence Based Practice Appraisal tool was used for quality appraisal. Results: Twelve interventional studies met criteria for inclusion. Four studies significantly reduced fatigue, with an additional 3 showing a reduction in fatigue. Interventions that utilized both problem and emotion-focused coping were more effective at reducing fatigue compared to interventions that only used emotion or problem-focused coping. Conclusion: This systematic review found moderate-strength evidence to support that coping interventions can reduce fatigue, with mixed, but mostly beneficial results. Clinicians caring for patients with hematologic malignancies should consider using coping interventions to reduce fatigue.
Effectiveness of damping and inertance of two dampers on mitigation of multimode vibrations of stay cables by using the finite difference method
Authors: Wang Yuanyuan , Li Shouying , Qie Kai , Zhou Shuai , Chen Zhengqing 
Published: May 2022

Stay cables of several cable-stayed bridges with a span of nearly 1000 m are confronted with the simultaneous actions of low-mode rain-wind induced vibration and high-mode vortex-induced vibration. It is difficult to effectively reduce these two kinds of cable vibrations by installing one damper at the end of the stay cable. In this paper, the effectiveness of two dampers attached at the lower end of the stay cable, including viscous dampers and viscous inertial mass dampers, is investigated by the finite difference method. First, the stay cable was simplified as an inclined cable with sag, and equation of motion governing the stay cable attached with two dampers was derived. This equation was then numerically solved by the finite difference method. Second, taking Cable A30 of the Suzhou-Nantong Yangtze River Bridge as a reference, a series of numerical simulations were carefully conducted to obtain the damping ratios of the first fifty modes. The results show that it is impossible to enhance the damping ratios of all of the concerned modes up to the minimum target value only by installing a single viscous damper or a single viscous inertial mass damper at the end of the stay cable. However, two viscous dampers installed at the lower end of the cable ( l1/ l = 2%, l2/ l = 5%) can overcome the shortcoming of a single viscous damper or viscous inertial mass damper to enhance the damping ratios of the first 34 modes up to the minimum target value (0.5%). In general, the optimized relative location of the two dampers ( l2/ l1) should be near 2. The optimized ratio of the damping coefficients ( η1/ η2) should be lower than l2/ l1, and the lower limit of η1/ η2 is determined by the minimum target values for modal damping ratios. Moreover, it appears that a lower installation position of two viscous dampers can realize the mitigation of higher modes even up to the 40th ∼ 50th modes.
Prospective Associations Between Early Childhood Intimate Partner Violence Exposure and Middle Childhood Internalizing and Externalizing Psychopathology
Authors: Lee Amy Hyoeun , Mirhashem Rebecca , Bernard Kristin , Dozier Mary 
Published: May 2022

Co-occurring adversities are common for young children with child protective services (CPS) involvement, with high rates of intimate partner violence (IPV) exposure in this population. Despite extensive research linking childhood IPV exposure to later psychopathology, fewer studies have examined the prospective associations between IPV exposure and psychopathology using a dimensional approach. Here, we conducted secondary analyses of data from a randomized controlled trial of a parenting intervention for CPS-involved children, examining the associations between early childhood IPV exposure (i.e., threat), co-occurring deprivation, and middle childhood internalizing and externalizing symptoms. Adversity variables were coded from data collected when children were infants ( N = 249, M age = 7.97 months) through 48-month assessments; internalizing and externalizing psychopathology were modeled as latent variables reflecting the mean of data from yearly assessments between ages 8 to 10. Results of our structural equation model demonstrated that, accounting for the effects of co-occurring deprivation, IPV exposure was significantly associated with both internalizing, β = .38, p = .001, and externalizing, β = .26, p = .019, symptoms. Results suggest links between early childhood IPV exposure (i.e., threat) and later psychopathology. Findings support screening and intervention efforts to mitigate the developmental sequelae of IPV exposure among CPS-involved children.