bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perceptions, experiences, barriers, facilitators, learning outcomes, and modes of assessment of digital clinical placements for pre-registration physiotherapy students internationally: a systematic review protocol
Authors: McConnell Justin , Rushton Alison , Noblet Tim , Pacey Verity , Mistry Jai , Lai Jeremy , Nguyen Daphne , Doralp Samantha 
Published: February 2025

Introduction
The shift to digital clinical placements for physiotherapy education due to COVID-19 prompts a need for evaluation of current evidence. Existing studies highlight benefits of digital technology in clinical placements, but lack of a systematic review focused on pre-registration physiotherapy students is a key gap. This systematic review will address this gap by synthesizing the evidence for digital clinical placements for pre-registration physiotherapy students internationally.

Methods and analysis
This systematic review is designed using the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) statement and Cochrane Handbook – it is registered on PROSPERO (CRD42024571696). Search terms will be adapted to each database, including EMBASE, MEDLINE, PROSPERO, ERIC, and CINAHL. Key journals, forward citation tracking, references of included studies, and professional organization websites will also be searched. The search will include studies published since database inception to 31/05/24. There will be no limit to study design or language. Studies that report on perceptions, experiences, barriers, facilitators, learning outcomes, and modes of assessment of digital clinical placements for pre-registration physiotherapy students will be included. Meta-aggregation will be used to synthesize themes from findings which enables the generation of themes without the need to re-interpret data and the loss of study specific context.

Ethics and dissemination
Ethics approval is not required. The results of this study will be written up for publication in relevant peer-reviewed scientific journals and contribute to a developing area of research. Results will also be presented at national or international conferences, events for the physiotherapy profession, or education events.
Maternal age and the rising incidence of hypertensive disorders of pregnancy: A comprehensive analysis of national claims data from Japan
Authors: Maeda Naomi , Koyama Masayuki , Takatsuka Shintaro , Oyatani Keisuke , Himuro Nobuaki , Mariya Tasuku , Kuno Yoshika , Hinotsu Shiro , Saito Tsuyoshi , Ohnishi Hirofumi 
Published: February 2025

Background
Hypertensive disorders of pregnancy (HDP) significantly increase the risk of developing hypertension and cardiovascular disease (CVD) later in life and are a major cause of maternal mortality. However, little is known about the nationwide, long-term, all-inclusive status of HDP.

Objective
To estimate the incidence of HDP from 2011 to 2019 in Hokkaido, Japan, with a focus on age groups.

Methods
Using National Database (NDB) insurance medical data, a retrospective analysis was conducted. Due to the absence of direct pregnancy data, birth numbers were used as a surrogate for the number of pregnant women to calculate the incidence of HDP.

Results
The average incidence rate of HDP over 9 years was 6.37%. The incidence rate was lowest among women aged 25–29 years, at 5.58% (95% confidence interval [CI]: 5.43–5.73), and increased with age, peaking at 10.58% (95% CI: 10.10–11.09) among women over 40 years. Notably, the incidence rate for women under 20 years of age was 6.70% (95% CI: 5.97–7.51), which was higher than that for women in their 20s. A mean annual increase of 0.25% in age-adjusted incidence was observed during this period, which was statistically significant (R² =  0.87, p <  0.01).

Conclusion
This study reveals that the risk of developing HDP is associated with both older childbearing and younger pregnancies and follows a J-curve, suggesting that factors other than maternal aging also contribute to the increased incidence of HDP and that further research on risk factors for HDP, which is on the rise worldwide, is urgently needed.
Professionalisierung durch Kollaboration: OER im Verbund
Authors: Clauss Daniela , Hirsch-Weber Andreas , Schumacher Kevin , Sielaff Lisa , Tangen Diana M. 
Published: February 2025

Zusammenfassung
Vorliegender Artikel beschreibt die Gelingensbedingungen eines für unterschiedliche Hochschularten zielgruppenspezifisch anpassbaren OER-Portfolios in den Bereichen Informations- und Schreibkompetenzen. Im Fokus steht dabei die Organisation einer strategischen OER-Partnerschaft. Die zum Erfolg notwendigen Maßnahmen werden aufgefächert und als mögliche Anknüpfungspunkte für ähnliche Vorhaben identifiziert. Abschließend wird die Frage gestellt, ob neue disziplinäre Zusammenhänge notwendig sind, um die hochschuldidaktische Professionalisierung im Feld voranzutreiben.
Evaluation of the add on effect of Majoone Sarkhas with levothyroxine in primary hypothyroidism: a randomized standard control adjuvant clinical study
Authors: Alam Md Anzar , Quamri Mohd Aleemuddin , Sofi Ghulamuddin , Haider Nafis 
Published: February 2025

Abstract

Objectives
Primary hypothyroidism is a prevalent endocrine disorder, typically treated with levothyroxine (LT). However, prolonged use of LT may result in complications and suboptimal outcomes for some patients. Majoone Sarkhas (MS), is a polyherbal formulation comprises four plants: Commiphora mukul, Operculina turpethum, Embelia tseriam-cottam, and Dryopteris filix-mas. It is traditionally used in Unani medicine for managing hypothyroidism associated conditions. The aim of this study was to assess the synergistic effect of Majoone Sarkhas in combination with LT for the treatment of primary hypothyroidism.

Methods
This randomized, single blind, standard clinical trial involved 100 subjects allocated into two groups: an adjuvant treatment group (n=50) and a standard control group (n=50). The adjuvant group received 10 g of MS twice daily in addition LT once daily, while the control group was treated with LT alone once daily. Both groups underwent treatment for 60 days. Changes in thyroid-stimulating hormone (TSH), free tri-iodothyronine (FT3), and free-thyroxine (FT4) levels from baseline to the 60th day were recorded and analyzed statistically to evaluate the outcomes.

Results
The study showed adjuvant group (MS + LT) had more reduction (4.99 vs. 3.93) in serum TSH level in comparison to control group (LT), which was statistically significant (p<0.001), it also showed increase in serum FT3 (2.88 ± 0.31 vs. 2.97 ± 0.44) and FT4 (1.06 ± 0.17 vs. 1.20 ± 0.27) levels, when compared with baseline values and after completion of trial.

Conclusions
The change in thyroid function profiles among adjuvant group, receiving MS with LT in primary hypothyroidism was both clinically and statistically significant. The safety parameters those were followed by serum level of ALT, AST, blood urea and serum creatinine were within the range, indicating the MS is safe medication to be used as an adjuvant therapy with LT (Clinical Trial Registration Code: CTRI/2018/02/011962).
The Play A Maiden’s Love by Maria Kuncewiczowa as an Example of a Representation of the subject of Abortion in Polish Interwar Theatre
Authors: Obarska Marcelina 
Published: February 2025

Abstract
Reproductive rights in Poland have been subject to fight for more than a hundred years. Since Polish independence in 1918, the topic of abortion has been present in literary forms of female artistic expression. One such play is A Maiden’s Love written by Maria Kuncewiczowa in 1932. The protagonist, a young woman named Inka, faces a weighty choice of whether to maintain the pregnancy having been left alone with this decision by her partner. In 1932 the piece was staged in Teatr Maly in Warsaw and widely discussed in the newspapers and magazines. It was also a year when a new penal code was established and abortion was criminalized. The Maiden’s Love conveys that theater can be considered as a form of social relation and that it is inherently interwoven with socio-political and economic discourse. In this paper, I would like to analyse Kuncewiczowa’s strategies for representing the subject of abortion as well as the reception and the critical discourse around of the play from Teatr Maly. I would also like to demonstrate the political potentialites in melodrama.
Influence of seawater condition on shear strength of CFRP single lap bonded joints with various fiber orientation
Authors: Nurtiasto Taufiq Satrio , Abdurohman Kosim , Pratomo Rezky Agung , Ramadhan Redha Akbar , Hidayat Ryan , Ardiansyah Riki , Pratama Mikhael Gilang Pribadi Putra , Wandono Fajar Ari , Aritonang Rian Suari , Nugroho Afid , Nuranto Awang Rahmadi , Targani Dudi , Prabowo Aditya Rio 
Published: February 2025

Abstract
This study investigates the impact of seawater conditions on the single-lap joint properties of carbon fiber-reinforced vinyl ester resin (CFRP) with various fiber orientations (0°, 45°, and 90°). Specimens were tested under dry, wet, and dried conditions, with seawater immersion durations of 15 and 30 days, followed by a drying process. The failure modes, surface conditions, and chemical bonds were analyzed to understand the mechanism of influence of seawater on lap shear properties. The results show that fiber orientation significantly affects shear strength, with 0° specimens demonstrating the highest shear strength. In contrast, 45° and 90° orientations experienced substantial reductions. Seawater immersion decreased shear strength across all orientations. However, post-immersion drying restored and enhanced shear strength in 0° specimens, provided partial recovery in 45° specimens, and had limited effect on 90° specimens. Surface treatments improved bonding quality, and FTIR analysis indicated no significant permanent chemical changes due to seawater exposure. This research highlights the importance of fiber orientation in CFRP joint design for aerospace and marine applications. It suggests further exploration into long-term environmental effects and advanced surface treatments to enhance performance and durability.
A World of Ideas: Selected Encounters in Architectural History and Philosophical Aesthetics, 1940–80
Authors: Martin Reinhold 
Published: February 2025

Abstract
This article reconstructs a series of encounters between architectural history and philosophical aesthetics in the postwar decades by comparing the discourse of two journals: the Journal of the Society of Architectural Historians and the Journal of Aesthetics and Art Criticism. Shared hermeneutic concepts including “space,” “style,” and “symbol” gained new meaning as historians of architectural modernism drew on, and contributed to, developments within Anglophone analytic thought. For philosophers as well as historians of art and architecture, including early advocates of social history, Panofskian iconology introduced a tension between idealist and materialist approaches that reappeared in the work of figures bridging these discourses, such as James Ackerman, Nelson Goodman, Susanne K. Langer, and Paul Zucker. This tension was temporarily resolved, on the one hand, by a critique of architectural ideology inspired by the New Left, and on the other, by a politically conservative aesthetics of cultural training, most notably advanced by the philosopher Roger Scruton.
Palladio and the “Secrets” of Architectural Proportion
Authors: Hemsoll David 
Published: February 2025

Abstract
The use of architectural dimensions and proportions in Palladio’s work has been an extremely contentious matter ever since the publication in 1949 of Rudolf Wittkower’s Architectural Principles in the Age of Humanism. Opinion is currently divided between those who, like Wittkower, believe that the dimensions Palladio provided in his treatise are highly significant and were based on ingenious numerical systems and those who regard them as playing only a marginal role in Palladio’s architecture and its understanding. This article reassesses how Palladio addressed the matter in his treatise, providing fresh insights into the theoretical basis and the complexities of his approach, while positing that the treatise illustrations are close records of his original designs before they were modified during execution. The conclusions reached here call attention to Palladio’s distinctive methods and their remarkable adroitness and effectiveness.
Dysthyroid optic neuropathy treated with tocilizumab
Authors: Yan Yuerong , Cai Zhaoxi , Ren Meng , Li Xiaohui , Yang Rongxue , Huang Cheng , Zhang Zhuo , Gong Xun , Wang Xiaoyi , Xu Mingtong 
Published: February 2025

Summary
Dysthyroid optic neuropathy (DON) is the most serious complication associated with Graves’ orbitopathy (GO). The primary treatment approach for DON is high-dose intravenous methylprednisolone infusion and decompression surgery. However, not all patients are suitable candidates for or can tolerate these two treatment options. Here, we present a patient diagnosed with DON in the left eye and central serous chorioretinopathy (CSC) in the right eye. Considering that glucocorticoids are contraindicated for CSC and that the patient refused orbital surgery, we opted for intravenous tocilizumab (6 doses of 8 mg/kg every 4 weeks), a monoclonal antibody against the interleukin-6 receptor. After tocilizumab infusion, the disease severity in the left eye improved from DON to moderate to severe GO, with magnetic resonance imaging showing a considerable reduction in inflammation in all affected muscles. Moreover, no adverse effects were observed in this patient. Similarly, two case reports and an observational study including nine patients with DON showed good clinical results after tocilizumab infusion, with no adverse effects having been observed. Our patient was primarily treated with tocilizumab just like one of the previous cases who had uncontrolled diabetes. Tocilizumab could potentially be considered one of the treatment options for DON patients, especially those in whom glucocorticoid therapy is inappropriate. Nonetheless, high-quality studies are warranted to verify the indications for this treatment.

Learning points

Not all patients with DON are suitable candidates for or can tolerate intravenous methylprednisolone infusion.

Tocilizumab, a monoclonal antibody against the interleukin-6 receptor, has been recommended as the second-line option for patients with active moderate to severe steroid-resistant GO.

Tocilizumab could potentially be considered one of the treatment options for DON patients, especially those in whom glucocorticoid therapy is inappropriate.
Improving Length of Stay by Reducing High-Flow Nasal Cannula Duration in Respiratory Illnesses
Authors: Hunter Brittany M. , Castiglioni Cynthia , Nellis Abigail B. , Wood Anna R. , Giblin Brian , Malakooti Marcelo , Stephen Rebecca J. 
Published: February 2025

OBJECTIVE
Despite limited evidence for generalized use, high-flow nasal cannula (HFNC) use continues to increase in acute respiratory illnesses. We aimed to reduce HFNC length of treatment (LOT) and length of stay (LOS) by 10% for patients aged 1 month to 5 years with bronchiolitis, pneumonia, or asthma receiving HFNC in the emergency department, pediatric floor, or pediatric intensive care unit.

METHODS
Using quality improvement (QI) methods, a multidisciplinary team implemented a weaning algorithm incorporating rapid weaning and discontinuation of HFNC at weight-based flow rates (Holiday). Primary outcome measures were LOT and LOS. Process measures included mean weight-based flow rate at HFNC discontinuation and Holiday occurrences. Balancing measures included readmission rates and positive pressure ventilation (PPV) following a Holiday. Intervention impact was monitored using run charts and statistical process control charts.

RESULTS
A total of 430 patient encounters were included, with 281 in the baseline phase and 149 in the improvement phase. Mean LOT decreased from 55.7 to 39.7 hours. Mean LOS decreased from 94.3 to 70.6 hours. Mean weight-based flow rate at HFNC discontinuation increased from 0.6 L/kg/min to 0.9 L/kg/min. Holiday occurrences increased from 10.9% to 82.8%. All improvements showed nonrandom signal or special cause variation (SCV) on control charts. Use of PPV and readmissions were uncommon before and after the intervention.

CONCLUSIONS
Using QI methodology to implement a weaning algorithm with rapid discontinuation of HFNC at weight-based flow rates for patients with bronchiolitis, pneumonia, and asthma was associated with a 29% reduction in LOT and 25% reduction in LOS.
Secondary Attack of Symptomatic SARS-CoV-2 Infections Among Roommates in a Children’s Hospital
Authors: Ikuse Tatsuki , Yamada Masaki , Kasai Taketo , Aiba Hiroyuki , Matsui Toshihiro , Funaki Takanori , Shoji Kensuke , Kato Ito , Miura Sachiko , Sugahara Yoshie , Ogimi Chikara 
Published: February 2025

BACKGROUND
SARS-CoV-2 can potentially cause nosocomial outbreaks. Although high secondary attack rates (SARs) among adult roommates have been reported, data on pediatric settings are limited. This study aimed to evaluate the SAR of symptomatic SARS-CoV-2 infections in shared rooms in a children’s hospital.

METHODS
A retrospective chart review from January 1, 2023, to December 31, 2023, was conducted at the National Center for Child Health and Development, one of the largest tertiary children’s hospitals in Japan. According to hospital policy, nucleic acid amplification tests for SARS-CoV-2 were required for all hospitalized patients who developed new-onset fever or respiratory symptoms during the study period. If the test result was positive, confirmed cases with SARS-CoV-2 infection were immediately transferred to an isolation ward, and their remaining roommates were closely monitored for 5 days following the diagnosis of the index case. The SAR of symptomatic SARS-CoV-2 infections among roommates was calculated.

RESULTS
Eighteen patients were identified as index cases with whom a total of 53 roommates had contact. Among these exposed roommates, secondary symptomatic SARS-CoV-2 infections occurred in 2 shared rooms, and the SAR within 5 days after the exposure from the index case was 5.7% (3/53).

CONCLUSIONS
The SAR of symptomatic SARS-CoV-2 infections in the largest tertiary children’s hospital in Japan was not high in this study. Further studies are warranted to validate our findings and to establish effective isolation and surveillance strategies for SARS-CoV-2 in hospitalized children.
Modelo del OLC desde sus precedentes bajo análisis conceptual y la articulación del proceso emprendedor en el contexto de América Latina
Authors: Porras Jiménez Jaime Augusto 
Published: February 2025

The study is based on a theoretical-conceptual overture that presents the foundation of the epistemological scenario of the Organizational Life Cycle OLC with the challenge of transcending epistemological scenarios, that is, referring to knowledge and learning. Simultaneously, it addresses the predominant approach of the entrepreneurial process and a complex alternative from the perspective of Latin America with a proposal to articulate the OLC model found. The methodological design of the study includes a qualitative approach, and categories of analysis related to the approaches, stages or phases of the OLC and the criteria for selecting the sample of the OLC models around which documentary and content analysis was carried out.

The results are presented referring to the relevant approaches of the OLC, the trends of the general characteristics of the OLCs, as well as six emphases of the approaches found and the findings on the most relevant disaggregated thematic emphases. Subsequently, the results of the articulation of the phases of entrepreneurship in the context of Latin America are presented to the general OLC model found and proposed, in order to advance as a pattern for subsequent studies, research, and actions and feedback related to the determination of policies and program design, as well as a management guide in organizations.
Sustentabilidad en las organizaciones del mercado de los residuos sólidos domiciliarios aprovechables en Neiva (Colombia): un análisis desde la Dinámica de Sistemas
Authors: Sánchez-Muñoz María Del Pilar , Giraldo Uribe José Jardani , Ruíz Agudelo Héctor Hugo 
Published: February 2025

Organizations that interact in the management of reusable household solid waste, with the passage of time, are exposed to difficulties in walking on the path of sustainability. In this article, it builds a model for the sustainability of the usable household solid waste market in Neiva, Colombia, to simulate two scenarios of public policy intervention strategies, in a 30-year horizon, using a qualitative methodology through the Dynamics of Systems and the semi-structured interview. Among the results, the need to make the price work as a mechanism of interaction between buyers and sellers stands out, but with the necessary regulation of prices by the State. As conclusion, concentrated strategies only to affect supply are not enough in the long term. It is also necessary to establish, simultaneously, strategies that encourage demand, in such a way that the profitability of recycling organizations increase. It is also necessary to simultaneously establish strategies to stimulate demand in order to increase the profitability of recycling organizations, improve the income of waste pickers and contribute to the environment, by reducing the amount of solid waste that go to the Los Angeles Landfill, thanks to the circular economy adopted by the industry that uses this waste as raw material
Mapping of Ethno-Cultural Landscapes of the Indigenous Peoples of the North of Yakutia
Authors: Degteva Z. F. 
Published: February 2025

Aim. We determine the specifics of mapping complex territorial systems, i.e. ethno-cultural landscapes, in order to meet the challenges of preserving languages and cultural heritage of indigenous peoples.Methodology. The paper uses the cartographic method to study ethnocultural landscapes of indigenous peoples. It examines and analyzes theoretical foundations and various approaches to ethnocultural landscape mapping. The specifics of ethnic culture and regional features of the territory under study are analyzed and thematic datasets are defined. The basic principles of mapping are proposed to be considered on the methodological basis of the systematic approach, which ensures the integrity and interconnectedness of all components of the ethnocultural landscape in mapping.Results. The need for a special approach to mapping ethnocultural landscapes of indigenous peoples of Russia is identified. The main mapping units are established to display the modern state of ethnocultural landscapes.Research implications. A comprehensive approach to mapping contemporary ethnocultural landscapes of small indigenous peoples is proposed, making it possible to identify patterns of spatial differentiation and gain insight into the development and transformation of ethnocultural territorial systems. This, in turn, will make it possible to solve a number of strategic tasks for the preservation of unique cultural heritage of Russia’s indigenous minorities.