bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation and assessment of adverse drug reactions at a tertiary care hospital
Authors: Pawar Prashant Ashok , Deshmukh Tushar Atmaram , Naik Jitendra B. 
Published: April 2022

Background: Improvement of patient care and safety in relation to the use of medicines with medical and paramedical interventions remains to be an important parameter. Adverse drug reactions have proved a significant problem in healthcare for a decade. The main aim of ADRs monitoring is to the promoting rational use of drugs, safe use of medicines improving patient care, improving public health. Objectives: The study aimed to determine the prevalence of ADRs in a tertiary care hospital to generating data safety of medications. Materials and Methods: The Prospective, observational study was conducted in the wards of a tertiary care Hospital. All patients were monitored for ADRs during their admission period. ADRs are a common occurrence but are often not recognized. Even if recognized, they are underreported as many physicians are unaware that all ADRs should be reported to ADR monitoring centers. Results and Discussion: Over the study period of two years, a total of 325 patients reports were monitored. The ADRs observed were higher in male patients and the highest number of ADRs were reported in the case of Sacubitril/valsartan followed by Amlodipine and in most of the cases drug is withdrawn.
Impact of mindfulness meditation on perceived stress levels and subjective well-being among housewives
Authors: Rattan Manpreet Kaur , Sood Meenakshi , Singh Gurvinder Pal 
Published: April 2022

Mindfulness meditation is paying attention to the current moment with openness, curiosity and with full acceptance. Mindfulness in every day experiences is best strengthened and supported by a regular meditation practice. This review aimed to identify the impact of Mindfulness meditation on the different sections of the society. A systematic search strategy was conducted with through online databases-Medline , PubMed, SCOPUS,Embase,Goggle Scholar, Cochrane library. The grey literatures from relevant websites were also searched. The keywords were indentified and used to search the literature published from 2007-2020 in English. More than 50 papers published related to this area were reviewed. It was found that people to deal with plenty of psychological problems related to stress, burnout, and fatigue. Mindfulness helps them in having more awareness regarding their inner as compare to their outer and that would captivate their performance in every aspect. Many studies shows evidence – based implementation plan contributes in the psychological well being of students .Conclusion: Mindfulness interventions found very useful for reducing the psychological distress. Further implications include the MBSR (mindfulness based stress reduction) potentially beneficial for oncology nursing intervention as they exposed to more stressful conditions.
Influence of social media on youth
Authors: Yachna Yachna , Sharma Rohini , Paul Ankita , Gupta Daksh , Kishore Kamal , Mondol Sujan 
Published: April 2022

Internet makes a large offering on online that connect a hard and fast of section that interacts and change knowledge. Some considerably used social systems collectively with Face book, Twitter, Whatsapp, and Instagram. It has come to be part of all people's life. Social media is a totally vast time period and virtually encompasses numerous different sorts of media, consisting of videos, blogs, etc. It is an area wherein you may transmit statistics approximately different human beings. Social networking is a automobile. It allows all people proportion content material that different human beings can proportion, in turn, with their on-line connections. It offers youths with more than a few blessings and probability to authorize them in numerous methods. Youths can retain civil relationship and may get admission to more statistics than ever before. It has come to be an area where in we spend many hours of the motive of enterprise or entertainment or interact with others or different ambition. The gift have a look at tries to discover the effect of youth with inside the utilization of social media particularly university college students.
comparative study of honey, jaggery an ethanol as cytological fixatives
Authors: Aggarwal Manish , Sharma Manish , Karthikeyan R. , Kumar Manish , Chawla Gurveen , Tyagi Vineet 
Published: April 2022

The processing of cytological samples. It is the gold standard cytological fixative used in many laboratories. However, it is an expensive, volatile and flammable liquid with an irritant smell. It has also been shown to be carcinogenic in some animal models. Hence, a need to identify a safer substitute of alcohol cytological fixative is necessary. The aim of study was to analyse the efficacy of cytological smears fixed in ethanol & 20% unprocessed honey and 30% jaggery solution and to compare the efficacy between the three fixatives on staining. Three buccal smears from 50 healthy volunteers each, were collected from either cheek or tongue using wooden spatula. One of the smear was fixed in ethanol (95%) and Rapid Papanicolaou staining was done. And the other two smear was fixed in honey (20%) and Jaggery (30%) and Rapid Papanicolaou staining was done. The cytoplasmic and nuclear details were evaluated using following parameters:- nuclear staining, cytoplasmic staining, cell morphology, clarity of staining and uniformity of staining. The results were recorded by 2 independent oral pathologists. Pearson Chi square test and Bonferroni post hoc test were used for comparison of qualitative data.
Antibacterial and antioxidant activity of flavonoid, glycoside and alkaloid extracts of Tilia Cordata
Authors: Ali Sahar A. , Al-Atbi Hala Sabry , Moein Furqan , Ali Basim M. 
Published: April 2022

About 12,000 chemical compounds isolated from medicinal plants and used to conduct crucial biological functions. These phytochemicals offer long-term health benefits for humans, thus they can be used effectively for treat a variety of human ailments. The goal of this study was to assess the in vitro free radical scavenging and antibacterial activities of glycoside, flavonoid and alkaloid extracts of Tilia cordata plant. According to the findings, flavonoid extract exhibits strong inhibitory action against Staphylococcus aureus but no activity against Escherichia coli. The free radical scavenging activity exhibited that the flavonoid extract was more effective in inhibiting lipid peroxidation more than alkaloid extract, whereas the glycoside extract had no antioxidant activity.
Short study of acute appendicitis cases in pediatrics age groups
Authors: Jarrah Mohammed Kadhem Ziedan Al 
Published: April 2022

Acute abdominal pain in children represent a diagnostic dilemma, generally although many causes of acute abdomen are benign, other require rapid diagnosis and treatment to minimize morbidity. Numerous disorders can cause abdominal pain. The most common surgical cause is acute appendicitis. This study tries to evaluates the distribution of cases through the age and the fate of the management and complications that may occur during the course of the disease. This is a prospective study over a period of six months starting from March 15th to September 15th 2018. A total of 82 child were included in this study who are presented to our hospital complaining of acute appendicitis. The patients divided in to three groups according to their age, undergo careful clinical evaluation supplemented by laboratory and radiological investigations followed by surgical intervention and histopathological study. Eighty – two child suffering from acute appendicitis were included in this study, 44 male and 38 female , those 82 case undergone surgical line of appendectomy, no line of conservative treatment was applied and no any case of appendicular mass was included in this study ,seven cases from those patients were presented with generalized peritonitis due to perforated appendices. F
The Effect of Leverage and Liquidity on Dividend Policy, Profitability as Intervening Variables
Authors: Pangestu Prayogo , Mahmudi Bambang 
Published: April 2022

The goal of this research is to see if Profitability, as measured by Return On Assets (ROA), can mediate the link between leverage and liquidity and dividend policy, as measured by the Debt To Equity Ratio (DER) and the Current Ratio (CR). The population for this study consisted of all coal mining sub-sector businesses that were registered on the Indonesia Stock Exchange between 2009 and 2018. The study employed the approach of purposive sampling. Path analysis and the Sobel test were the analytical models employed in this study. (1) Liquidity has no effect on Dividend Policy and is not significant (2) Leverage has no effect on Dividend Policy and is not significant (3) Leverage has no effect on Profitability and is not significant (4) Liquidity has no effect on Profitability and is not significant according to the findings of thisstudy. (5) Profitability has a strong and negative impact on dividend policy
Effect of the Enhanced Recovery After Surgery Protocol on Postoperative Cognitive Functions in Colorectal Surgery
Authors: Duran Yakar Nagihan , Yakar Mehmet Nuri , Polat Cengiz , Akdas Tekin Esra , Sivriköz Emre , Turgut Namigar 
Published: April 2022

Objective: Enhanced Recovery After Surgery (ERAS®) protocols established for colorectal surgery and continuing to develop are multidisciplinary approaches combining several evidence-based interventions to reduce the patient’s surgical stress response, to accelerate surgical recovery and to improve the outcome in all perioperative steps. However, it is not yet known how ERAS® protocols affect the cognitive functions in the early and late periods of patients.
Methods: Prospective observational study was performed with 51 cases. Mini Mental Test (MMT) was administered in the patients in the preoperative, postoperative early period (3rd hr,1st day) and postoperative late period (7th day, 30th day).
Results: Changes observed in MMT measurements during the period from the preoperative period to postoperative 30th day were determined to be statistically significant (P < .01). Decrease in postoperative 3rd hr and 24th hr measurements (P < .01), increase in the postoperative 24th hr, 7th day and 30th day measurements (P < .01), compared to the postoperative 3rd hr measurement; increase in the postoperative 7th day and 30th day measurements (P < .01), are statistically significant compared to the postoperative 24th hr measurement. When the differences between the preoperative and postoperative 30th day MMT measurements were considered; an improvement was observed with a rate of 76% (n=38). In the group observed improvement (Group I), ASA scores were lower (P < .01), and mobilization (P < .01), were earlier; lengths of in the intensive care unit stay (P < .01), were shorter.
Conclusion: Cognitive functions improve in the early period with ERAS® protocol and complication rate regresses significantly and it becomes cost efficient due to early discharge.
Malnutrition and Nutritional Care in Patients with COVID-19
Authors: Öztürk Yelda , Halil Meltem 
Published: April 2022

Malnutrition causes serious morbidities and mortalities for both individuals and communities burdens healthcare systems. Its prevalence has become higher during the coronavirus disease 2019 (COVID-19) pandemic. COVID-19 may lead to weight loss, loss of muscle mass, malnutrition, sarcopenia, frailty, and obesity not only at the time of disease but also after disease. Nutrition risk should be assessed for all patients, and individualized nutritional care plan including one during post discharge should be generated. The fact that the risk of malnutrition and loss of muscle mass continue even several months after disease should be considered. Being aware of the increased risk of malnutrition and loss of muscle mass and their consequences during COVID-19 and in the following months would be appropriate.
Brexit and Corporate Taxation: New Perspectives
Authors: Panayi Christiana HJI 
Published: May 2022

This article examines some of the salient legal features of the new post-Brexit relationship between the UK and the EU with the focus on corporate taxation. It reviews the status of EU corporate tax legislation in UK law at the time of writing, as well as the soft law obligations that have been agreed. The author questions whether the overall set up has the potential to generate more tax competition between the EU and the UK, rather than less, and whether the EU’s impending implementation of the OECD/G20’s Pillar Two will exacerbate this.
Brexit, corporate taxation, retained EU law, soft law, competitiveness, case study
Pré-mediação e seus objetivos para partes e mediadores
Authors: Almeida Gustavo Milaré 
Published: May 2022

This text aims to specify and analyze the objectives of pre-mediation for the parties and for the mediator, in order to assess the need for possible changes in Brazilian legislation. The purpose is to contribute to the debate on the practice of mediation and, therefore, to the constant and necessary improvement of this ADR in Brazil.
Pre-mediation; mediation; objectives; parties; mediator.
Reforming the BRI from the Inside: Japan’s Contribution via Soft Law Diplomacy
Authors: Umirdinov Alisher 
Published: May 2022

‘Deep-free trade agreements (FTA)-maker-multilateralist’ nations are obliged to find unconventional ways to co-exist with China in countries along the Belt and Road Initiative (BRI); and this obligation is becoming more obvious. There is a possibility for Japan’s involvement in enlisting soft law mechanisms in order to ensure China’s BRI projects conform to high standards; and this serves as a main argument of this article. In my view, with its unique geographic position, the existing fierce rivalry in the Association of Southeast Asian Nations, and the country’s intertwining market with China, Japan’s capacity to reform the BRI from the inside should not be underestimated. On the contrary, by persisting with high Quality Infrastructure Investment (QII) principles promoted in the last three years, Japan has been successful in nudging China toward these principles. The country has also enabled China to endorse the notion of high-quality infrastructure at the second BRI forum. With Japan’s leadership, the G20 Osaka Summit has contributed considerably into bolstering of the QII principles. Moreover, despite being less institutionalized and having soft law nature, the Japan-China Memorandum on Business Cooperation in Third Countries is effective: The Memorandum utilizes and suppresses the harm caused by the economic activities of Chinese businesses in third-country markets. Presently, Sino-Japanese collaboration in Thailand’s East- West Economic Corridor Program is testing whether the Chinese government is capable of earnestly engaging in ‘Third Party Market Cooperation’, or whether this endeavour is futile.
BRI, FOIP, quality infrastructure, third-party market cooperation forum, China-Japan Relations
INFLUENCE OF BRAND IMAGE, PRICE, AND PRODUCT REVIEW ON PRODUCT PURCHASE INTEREST IN LAZADA
Authors: Andarini Sonja , Kurniawan Akbar Tri 
Published: April 2022

This study aims to determine the effect of brand image, price, and product reviews on product repurchase intention in Lazada Indonesia. The population in this study are consumers who use Lazada Indonesia's e-commerce services and who have made transaction purchases at least once. This study used a sample of 109 respondents. The sampling technique used was purposive sampling with the following criteria: (1) lazada Indonesian e-commerce service users are at least 17 years old, and (2) have made at least one purchase at di lazada.co.id. The data analysis technique uses the Multiple Linear Regression analysis method with IBM Statistic 22 software.
The results of this study indicate that brand image has a positive and significant effect on repurchase intention. In contrast, the price variable has a positive and insignificant effect on repurchase intention. Moreover, product review variables have a negative and insignificant effect on repurchase intention.
Zdrowie w pismach polskiego renesansu
Authors: Smoła Marek 
Published: April 2022

Krótka analiza literatury naukowej, medycznej i traktatów pedagogicznych z epoki renesansu, pozwala na wskazanie licznych wątków związanych ze zdrowiem i sprawnością fizyczną, którym swoją uwagę poświęcali polscy autorzy. Nie wszystkie ich twierdzenia były oryginalne, wiele treści powtarzali za starożytnymi uczonymi. Z drugiej strony podejmowali samodzielne rozważania, formułując – także i naiwnie – różne błędne twierdzenia. Dorobek ten wart jest dostrzeżenia. Wspominani – nie wszyscy przecież – uczeni (teoretycy i praktycy) byli w wielu przypadkach prekursorami tez i pomysłodawcami pewnych działań, które w swoim czasie bez wątpienia staną się nowatorskie.
Treaty-Based Nondiscrimination: Now You See It Now You Don't
Authors: Goldberg Sanford H. , Glicklich Peter A. 
Published: May 2022

A broad nondiscrimination provision appears in every income tax treaty that the United States has entered into in the last quarter century. The nondiscrimination article of these treaties purports to prohibit discriminatory taxes levied against foreign nationals or their businesses. However, some distinctions have always been permitted, based on the fact that domestic and foreign taxpayers are not similarly situated because different taxing jurisdictions are concerned. The problem is that it is difficult to articulate a consistent and rational standard to apply to determine when proscribed discrimination is present.The language used in a typical U.S. nondiscrimination provision, such as Article 24 of the 1981 U.S. Model Income Tax Treaty (the "1981 U.S. Model"), can be traced to the 1963 draft model convention published by the Organization for Economic Cooperation and Development Committee on Fiscal Affairs, Draft Double Taxation Convention on Income and on Capital (the "1963 OECD Model"). The 1977 draft of the Organization for Economic Cooperation and Development Model Double Taxation Convention on Income and on Capital (the "1977 OECD Model") includes a similar provision as its Article 24. Both the 1963 OECD Model and the 1977 OECD Model have been instrumental in guiding development of the language of bilateral income tax treaties. Copies of Article 24 of the 1981 U.S. Model and of Article 24 of the 1977 OECD Model are attached as Appendix A and Appendix B.
Tax Amnesty: An Old Debate as Viewed From Current Public Choices
Authors: Moran Gerald P. 
Published: May 2022

The Clinton administration arrived with specific, well-advertised goals: job creation, a comprehensive national health care program, economic recovery and a commitment to reduce the constantly increasing federal deficit. There is no question that President Clinton has established these policy objectives as the primary criteria upon which he desires his forthcoming leadership efforts to be judged by the electorate. Success on these domestic issues would enhance his position for re-election in 1996, and would merit well-deserved respect for leadership and judgment. Whether all of these separate but related goals can be achieved within both the short and long term, without being counter-productive to each other, presents one of the more intriguing enigmas faced by the administration.Job creation and a comprehensive national health care program will necessarily consume more revenue in the short term. Consequently, the federal deficit will increase unless new resources are found to pay the costs of these programs and unless acquisition of such resources does not significantly impair the economic recovery in progress. Indeed, the current economic recovery can, on its own, deliver significant dividends. Nevertheless, the search for resources will be one of the more consuming and politically sensitive issues facing President Clinton. The new resources may be generated by any of the following items: (I) a cut in government expenditures, including mandatory programs; (2) an economic dividend generated through restructuring of the health delivery system; and (3) an increase in tax revenues. Notwithstanding the anticipated economic dividend to be generated from the restructuring of a health delivery system, it is likely that only cuts in federal expenditures coupled with increased tax revenues will provide the funds necessary to attain and sustain President Clinton's goals as laid out in his State of the Union Address.
The Fallacious Objections to the Tax Treatment of Carried Interest
Authors: Kahn Douglas A. , Kahn Jeffrey H. 
Published: May 2022

The tax treatment of carried interest has become a notorious bete noire for many politicians and some academicians and practitioners. Both 2016 presidential candidates denounced the current tax treatment and vowed to change it. President Obama described the current treatment as a “tax loophole” which should be closed. Others have also characterized the current tax treatment as an abusive loophole. It is the thesis of this article that those criticisms are unfounded. To the contrary, the current tax treatment accords with sound tax policy and is proper and appropriate. Given the broad approval that attended the attacks on carried interest, a reader might well be skeptical of our claim; but if you will bear with us, we are convinced that we can sustain it.
Plasma and Hemocyanin Phenoloxidase Derived from the Hemolymph of Giant Freshwater Prawn Macrobrachium rosenbergii (De Man, 1879)
Authors: Ramasamy Sivakumar Mullaivanam , Shanthi Rangasamy 
Published: April 2022

We attempted to study the immune response in M. rosenbergii by melanization reaction produced by plasma phenoloxidase (PO) activity. The substrate affinity of the PO enzyme was determined using different phenolic substrates, and it was found that the diphenols were only oxidized. The enzyme was characterized as catechol oxidase type of PO and L-3,4 dihydroxyphenylalanine (L-DOPA) showed the highest substrate affinity to the enzyme. The biochemical parameters that determined optimum enzyme activity were found to be 2.5 mM L-DOPA at an absorbance of 470 nm, 10 mM Tris–HCl buffer at pH 7.5, temperature at 25°C, and 15 min incubation. Kinetic characteristics of plasma were studied from the M. rosenbergii. The hemocyanin was isolated by gel filtration chromatographic technique using Sephadex G-100. The M. rosenbergii hemocyanin (MrHC) showed only one band with a molecular weight of 325 kDa on native polyacrylamide gel electrophoresis (PAGE) when stained with Coomassie Brilliant Blue (CBB) and bathocuproine sulfonic acid. The reduction of MrHC protein in SDS-PAGE displayed three subunits with a molecular weight of 74, 76, and 78 kDa, respectively. Determination of optimal condition for PO activity of plasma has also been attempted. The plasma optimal condition taken for the MrHC was tested for its ability to oxidize diphenols such as L-DOPA was shown only PO activity. These results showed that in the presence of PO and peroxidase inhibitors, phenylthiourea (PTU) and tropolone respectively have decreased plasma and MrHC PO activity. This indicates that hemocyanin triggers innate immunity probably through one of its subunits that function as the active moiety.