bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cryopreservation of Plant Tissues in Poland: Research Contributions, Current Status, and Applications
Authors: Mikuła Anna , Chmielarz Paweł , Hazubska-Przybył Teresa , Kulus Dariusz , Maślanka Małgorzata , Pawłowska Bożena , Zimnoch-Guzowska Ewa 
Published: December 2022

Abstract
Cryopreservation of vegetatively propagated plant material is an increasingly widely used method for the efficient and safe storage of germplasm resources around the world. In Poland, there are currently four cryobanks in use for long-term plant protection programs. However, plant tissues propagated in vitro constitute only a small portion of the accessions stored in them. To date, cryogenic storage techniques have been developed and adopted in this country for ornamental plants (roses, chrysanthemums, and geophytes), crop species (potato and garlic), forest tree species (the genera
Quercus
and
Fraxinus
), and some ferns. Polish researchers have used suspension cultures of
Gentiana
spp. and shoot tips of
Lamprocapnos spectabilis
to improve cryopreservation knowledge. A better understanding of the benefits of cryopreservation and its widespread implementation in plant biodiversity conservation programs is required. The objective of this review is to provide a concise synthesis of the scientific contributions, current status, and applications of cryogenic techniques for the conservation of in vitro culture-derived plant tissues in Poland. First, the results contributing to research that has been achieved using cell suspensions and advances related to the use of nanoparticles and plant extracts to improve cryopreservation efficiency are discussed. Then, the applications and advances in cryopreservation of ornamental plants (roses, radiomutants, plant chimeras,
Lamprocapnos
spp., and geophytes), crop species (potato and garlic), forest trees, and ferns are summarized.
Genetic parameter estimates for growth performance of crossbred piglets
Authors: CHAUDHARY RAJNI , SAILO LALRENGPUII , SINGH AKANSHA , KARTHIKEYAN A , MEHROTRA ARNAV , MONDAL S K , SAHOO N R , KUMAR AMIT 
Published: December 2022

The direct heritability estimates for piglet weights in pre and post weaning stages were moderate and improvement through mass selection is plausible. In the pre-weaning stage, the piglets had maximum genetic potential at birth (BW) to be exploited through direct selection. The 3 random effects, namely direct additive, maternal additive and litterÂ permanent environmental effects had significant roles during different phases of pre-weaning growth and all must be included in the model used for formulating a breeding program. For post-weaning traits, the direct additive and permanent litter effects were the predominant factors governing the variability. The non-significance of postweaning maternal influence was as per expectation because the piglets moved away from maternal care after 8thweekof age.
Etické aspekty rozvoje umělé inteligence
Authors: Jedličková Anetta 
Published: December 2022

Počítačové zpracovávání dat s využitím umělé inteligence se ve veřejném sektoru i v komerční sféře postupně stává každodenní rutinou, a zásadně tak zasahuje do rozličných osobních oblastí života lidí. S výrazným rozvojem algoritmického rozhodování při zpracování dat prostřednictvím technologie strojového učení neboli machine learning se do popředí odborných diskusí dostávají také etické aspekty při vývoji, zavádění a používání systémů využívajících při své činnosti různou míru autonomního rozhodování umělé inteligence. Článek si v jednotlivých částech klade za cíl obeznámit odbornou i laickou veřejnost s etickými principy, které jsou diskutovány specialisty v různých etických pokynech zabývajících se umělou inteligencí, s etickými aspekty, jež provází vývoj, implementaci a využívání autonomních a inteligentních systémů, a v závěru obeznamuje s problematikou formování příslušného etického rámce z praktického pohledu.
Pengaruh E- Service Quality, E-Trust, E-Satisfaction Terhadap E-Loyalitas Nasabah Perbankan Indonesia
Authors: Mariana Yeni , Aidil Fadli Jul 
Published: December 2022

Di era digital saat ini dunia perbankan mulai berlomba lomba untuk menggunakan layanan elektronik, kepercayaan elektronik dan kepuasan elektronik terhadap loyalitas elektronik. Peran digital akhirnya akan mengukur variable elektronik tersebut pada nasabah perbankan yang menggunakan layanan elektronik perbankan di Indonesia. Penelitian ini dilakukan pada 199 nasabah perbankan Indonesia dengan menggunakan kuesioner, penelitian ini kuantitatif dengan metode Analisa regresi berganda. Hasil penelitian ini menunjukkan bahwa E-Service Quality berpengaruh positif terhadap E-Loyalitas pada nasabah Perbankan di Indonesia, E-Trust berpengaruh positif terhadap E-Loyalitas pada nasabah Perbankan di Indonesia. E-Satisfaction tidak berpengaruh positif terhadap E-Loyalitas pada nasabah Perbankan di Indonesia. Sedangkan secara Bersama sama variable E-Service Quality, E-Trust, E-Satisfaction berpengaruh positif terhadap E-Loyalitas pada nasabah perbankan di Indonesia. Untuk Peneliti selanjutnya menambah variabel lain yang dapat mempengaruhi E-Loyalitas karyawan, atau mengganti variabel penelitian lainnya sehingga mampu memperkaya dan hasil yang lebih komprehensif. Penelitian ini memberikan implikasi kepada Perbankan Indonesia agar mempertimbangkan E-Service Quality, E-Trust, E Satisfaction agar mampu meningkatkan E-Loyalitas sehingga tujuan perbankan dapat tercapai dengan efektif dan baik sesuai dengan yang diharapkan. Selain itu perlunya untuk lebih meneliti secara detail hubungan E-satisfaction terhadap loyalitas pada dunia perbankan Indonesia.
Meningkatkan Kemampuan Akademik Guru dalam Melaksanakan Pembelajaran Melalui Supervisi Individual dengan Pendekatan Kolaboratif Terhadap Guru Mata Pelajaran di Lingkungan SMP Pasundan I Bandung Tahun Pelajaran 2018 – 2019
Authors: Mulyana Nana 
Published: December 2022

Penelitian Tindakan Sekolah ini bertujuan untuk mengetahui langkah – langkah dan manfaat bimbingan yang tepat dalam melaksanakan supervisi dengan pendekatan kolaboratif di SMP Pasundan 1 Bandung, sehingga mampu membentuk komunitas pembelajaran yang dapat meningkatkan kompetensi guru dan mencapai supervisi akademik yang efektif. Penelitian ini terbagi kedalam dua siklus melalui bimbingan kolaboratif. Faktor-faktor yang diamati meliputi aktivitas guru, sikap minat guru, , dan sikap minat siswa. Hasil penelitian siklus II umumnya mengalami peningkatan jika dibandingkan dengan siklus I. Tugas seorang supervisor adalah mampu menerapkan teknik-teknik supervisi yang tepat dalam pelaksanaan kegiatan supervisi. Pemahaman dan penguasaan teknik-teknik tersebut oleh supervisor, menjadi suatu keharusan jika ingin pelaksanaan supervisi di sekolah/madrasah, dapat berjalan dengan baik sehingga dapat meningkatkan mutu pembelajaran. Tindakan Peneliti pada pelaksanaan supervisi siklus pertama sebagai berikut. (1) Peneliti memberikan indikator yang harus dicapai pada saat persiapan, pelaksanaan, dan penilaian sebelum pelaksanaan supervisi, (2) Peneliti menyuruh guru mengisi format penilaian serta membuat perencanaan kembali kegiatan berikut yang akan disupervisi. Berdasarkan hasil penelitian pada siklus II kegiatan supervisi individual dengan pendekatan kolaoratif dapat meningkatkan kualitas dan kuantitas rancangan pembelajaran serta implementasi pembelajaran yang mendidik. Hal ini disertai juga dengan meningkatnya aktivitas, sikap, minat guru dan siswa. Supervisi individual ini menjadi efektif melalui bimbingan kolaboratif dan terbentuknya komunitas pembelajaran profesional.
Upaya Legislasi Qanun Syari'ah Di India Dan Pakistan
Authors: Nursyamsi  , Dedi  , Ibnu Rusydi  
Published: December 2022

Tulisan ini bertujuan untuk mengkaji upaya legislasi Qanun dan Syariah di India dan Pakistan. Berbicara bagaimana informasi tentang Islam di India dan Pakistan, serta pergumulan yang terjadi di kawasan sekitarnya pasca terbentuknya kedua negera tersebut. Negara Pakistan merupakan hasil pemisahan dari negara India. Penelitian ini menyimpulkan bahwa upaya legislasi Qonun syariah yang diusung oleh kaum muslim di kedua negara tersebut memberikan nilai-nilai sejarah adanya keinginan yang sangat kuat, terlebih di negara Pakistan yang mayoritas penduduknya adalah muslim. Tampaknya masih disibukkan dengan persoalan identitas nasional, problem diferensisi visi di kalangan modernis dan tradisionalis atau pergumulan tentang peran sipil dan militer yang terjadi di Pakistan hingga kini terus terjadi.
STREPTOCOCCUS PNEUMONIAE SEROTYPE DISTRIBUTION AFTER THE INTRODUCTION OF PNEUMOCOCCAL CONJUGATE VACCINES
Authors: Malcheva Mariya 
Published: December 2022

Streptococcus pneumoniae serotypes are changing due to the widely introduced pneumococcal conjugate vaccines. Surveillance studies have proven valuable in monitoring these vaccine effects. S. pneumoniae is highly adaptable to its human reservoir and colonises mucosal surfaces of upper airways mainly in children. Carriage decreases during the first 2 years of life because of the development of naturally acquired adaptive immune memory. Most of the serotypes do not cause serious illnesses but few of them are responsible for severe pneumococcal infections. Ten of the most common serotypes are estimated to cause over 60% of invasive diseases worldwide. The virulence factor of S. pneumoniae is the polysaccharide capsule as non-encapsulated strains are absent among the strains causing invasive pneumococcal disease. Prevalence of serotypes differs depending on the age group and geographic area of patients. Differences in PCV implementation lead to changes in serotype distribution and to significant reduction of disease caused by vaccine types.
SURVEILLANCE DATA ON BACTERIAL ENTEROCOLITIS IN BULGARIA FOR 2014-2018
Authors: Pavlova Maria , Velev V. , Karageorgiev Miroslav , Alexandrova Ekaterina , Kamenov E. , Kantardjiev Todor 
Published: December 2022

Worldwide, 30% of cases of infectious diarrhoea are caused by bacterial pathogens. As in other countries of the European Union, in Bulgaria the most common etiological agents are Escherichia coli (STEC), Salmonella spp., Shigella spp., Campylobacter spp. and Yersinia enterocolitica. Acute gastroenteritis and enterocolitis infections are most common in young children. According to our survey, the leading pathogens for 2014-2018 are Salmonella spp., E. coli (EPEC, ETEC) and Campylobacter spp. The rate of infections caused by Shigella spp. is relatively high compared to other European countries.
The number of enterocolitis cases of undefined aetiology continues to increase because of the neglect towards diarrhoeal syndrome by patients who rarely visit a doctor or do not seek medical attention at all.
MOLECULAR EPIDEMIOLOGICAL ANALYSIS OF THE TRANSMISSION CLUSTERS OF THE HIV-1 CIRCULATING RECOMBINANT FORMS CRF01_AE AND CRF02_ AG IN BULGARIA
Authors: Alexiev Ivailo , Dimitrova Reneta , Gancheva Anna , Kostadinova Asya , Grigorova Lyubomira , Partsuneva Aleksandra , Elenkov I , Yancheva N , Stoycheva M , Doychinova T , Pekova L , Emilova Radoslava , Nikolova Maria 
Published: December 2022

Background. The purpose of this study was to analyse the underlying HIV transmission clusters of individuals from different vulnerable groups infected with the recombinant forms of HIV-1 – CRF01_AE and CRF02_AG, between 1986 and 2011 using sequencing and phylogenetic analysis.
Material and methods. Blood samples from randomly selected 242 individuals diagnosed with HIV-1 CRF01_AE and CRF02_AG in Bulgaria were analysed. HIV-1 pol gene fragment was sequenced using the ViroSeq HIV-1 Genotyping Test (Abbott) and/or TruGene DNA Sequencing System. The phylogenetic tree reconstruction was performed with the IQ-TREE program. Identification of the phylogenetic clusters was performed using the ClusterPicker program with two parameters to identify recent and distant infection.
Results.Two main local independent epidemics confined to different geographical regions of the country were caused by HIV-1 CRF01_AE and CRF02_AG. The various viral strains circulate predominantly in two major separate regions – CRF01_AE in Sofia and CRF02_AG in Plovdiv. Most of the individuals infected with viral strains analysed in this study were people who inject drugs (PWID) or heterosexuals and only a few were men who have sex with men. The phylogenetic analysis revealed transmission clusters in both recombinant forms, few in number when confined within a short period of time and multiple clusters over an extended timeframe.
Conclusions. The introduction and rapid spread of two different strains of HIV-1 into geographically distant groups of PWID triggered local epidemic outbreaks. The phylogenetic analysis indicated the accelerated transmission of HIV, which is a characteristic of the spread through injection practices. Our study demonstrated that transmission cluster monitoring is important for better understanding of the development of epidemic and could be used as a tool for the identification of risk indicator populations.
Elicia transficcionalizada: el retrato de la alcahueta en la <i>Tragicomedia de Lisandro y Roselia</i>
Authors: Francois Jeromine 
Published: December 2022

Este trabajo examina la resemantización del personaje de la alcahueta ofrecido por Sancho de Muñón en su Tragicomedia de Lisandro y Roselia. Analizar, en su dimensión caracteriológica así como en su aspecto funcional, el retrato de Elisa-Celestina construido en esta obra no solo permite entender mejor uno de los componentes de la tradición celestinesca en cuya elaboración incipiente estaba participando Muñón, sino que también esclarece las técnicas transficcionales que aseguran la conexión entre la alcahueta de la continuación y la Celestina de su modelo.
Decreasing Osteomyelitis Occurrence in Remaining Bone After Partially Resected Infected Bone
Authors: Karr Jeffrey C. 
Published: December 2022

Background: After partial bone resection for osteomyelitis there is a high rate of osteomyelitis occurrence in the remaining bone due to adherent bacterial biofilm, dysvascular infected spongiosum bone, and absence of a surgical technique that can prevent osteomyelitis developing in the remaining bone.
Methods: Presented is a surgical procedure using a dicalcium phosphate bone void filler putty with antibiotics placed into the remaining bone to prevent the development of osteomyelitis, therefore preventing amputation.
Results: This procedure has an osteomyelitis eradication rate of 94.8% and also decreases the rate of lower-extremity amputations.
Conclusions: This procedure provides a single stage surgical technique for infected open bone defects decreasing the previously reported high osteomyelitis reoccurrence rate of 57.1% to 5.2%.
Guava Pest App to Assist Farmers
Authors: Rani P. Jona Innisai 
Published: December 2022

In this paper, Guava Pest App is designed to identify the several diseases in Guava at early stage. Guava Pest App is an innovative application that is useful for farmers.
The farmers can capture the images from Guava farm and upload the images. Guava API is created and placed in cloud services. Images taken from farmers field matches with Guava API and gets the TNAU recommendation for the Guava fruit diseases.
Guava Pest App for pest management in Guava will analyze and provide an accurate recommendation to farmers about the type of pesticide for the symptoms given through the images This paper expresses the idea about the creation of Guava Pest App, an android application that helps to make management decision for cotton leaf symptoms. The study would provide a better understanding of the management practice required for the Guava fruit disease.
Fundamental Pathobiology of Coronary Atherosclerosis and Clinical Implications for Chronic Ischemic Heart Disease Management—The Plaque Hypothesis
Authors: Stone Peter H. , Libby Peter , Boden William E. 
Published: December 2022

ImportanceRecent clinical and imaging studies underscore that major adverse cardiac events (MACE) outcomes are associated not solely with severe coronary obstructions (ischemia hypothesis or stenosis hypothesis), but with the plaque burden along the entire coronary tree. New research clarifies the pathobiologic mechanisms responsible for plaque development/progression/destabilization leading to MACE (plaque hypothesis), but the translation of these insights to clinical management strategies has lagged. This narrative review elaborates the plaque hypothesis and explicates the current understanding of underlying pathobiologic mechanisms, the provocative destabilizing influences, the diagnostic and therapeutic implications, and their actionable clinical management approaches to optimize the management of patients with chronic coronary disease.ObservationsClinical trials of management strategies for patients with chronic coronary artery disease demonstrate that while MACE rate increases progressively with the anatomic extent of coronary disease, revascularization of the ischemia-producing obstruction does not forestall MACE. Most severely obstructive coronary lesions often remain quiescent and seldom destabilize to cause a MACE. Coronary lesions that later provoke acute myocardial infarction often do not narrow the lumen critically. Invasive and noninvasive imaging can identify the plaque anatomic characteristics (plaque burden, plaque topography, lipid content) and local hemodynamic/biomechanical characteristics (endothelial shear stress, plaque structural stress, axial plaque stress) that can indicate the propensity of individual plaques to provoke a MACE.Conclusions and RelevanceThe pathobiologic construct concerning the culprit region of a plaque most likely to cause a MACE (plaque hypothesis), which incorporates multiple convergent plaque features, informs the evolution of a new management strategy capable of identifying the high-risk portion of plaque wherever it is located along the course of the coronary artery. Ongoing investigations of high-risk plaque features, coupled with technical advances to enable prognostic characterization in real time and at the point of care, will soon enable evaluation of the entire length of the atheromatous coronary artery and broaden the target(s) of our therapeutic intervention to include all regions of the plaque (both flow limiting and nonflow limiting).
Association Between Alcohol Use Disorder and Receipt of Direct-Acting Antiviral Hepatitis C Virus Treatment
Authors: Haque Lamia Y. , Fiellin David A. , Tate Janet P. , Esserman Denise , Bhattacharya Debika , Butt Adeel A. , Crystal Stephen , Edelman E. Jennifer , Gordon Adam J. , Lim Joseph K. , Tetrault Jeanette M. , Williams Emily C. , Bryant Kendall , Cartwright Emily J. , Rentsch Christopher T. , Justice Amy C. , Lo Re Vincent , McGinnis Kathleen A. 
Published: December 2022

ImportanceDirect-acting antiviral (DAA) treatment for hepatitis C virus (HCV) infection is associated with lower mortality and is effective in individuals with alcohol use disorder (AUD). However, despite recommendations, patients with AUD may be less likely to receive DAAs.ObjectiveTo assess the association between alcohol use and receipt of DAA treatment among patients with HCV within the Veterans Health Administration (VHA).Design, Setting, and ParticipantsThis cohort study included 133 753 patients with HCV born from 1945 to 1965 who had completed the Alcohol Use Disorders Identification Test–Consumption (AUDIT-C) questionnaire and had at least 1 outpatient visit in the VHA from January 1, 2014, through May 31, 2017, with maximal follow-up of 3 years until May 31, 2020; DAA receipt; or death, whichever occurred first.ExposuresAlcohol use categories generated using responses to the AUDIT-C questionnaire and International Classification of Diseases, Ninth Revision and International Statistical Classification of Diseases and Related Health Problems, Tenth Revision diagnoses: current AUD, abstinent with AUD history, at-risk drinking, lower-risk drinking, and abstinent without AUD history. Demographic, other clinical, and pharmacy data were also collected.Main Outcomes and MeasuresAssociations between alcohol use categories and DAA receipt within 1 and 3 years estimated using Cox proportional hazards regression stratified by calendar year.ResultsOf 133 753 patients (130 103 men [97%]; mean [SD] age, 60.6 [4.5] years; and 73 493 White patients [55%]), 38% had current AUD, 12% were abstinent with a history of AUD, 6% reported at-risk drinking, 14% reported lower-risk drinking, and 30% were abstinent without a history of AUD. Receipt of DAA treatment within 1 year was 7%, 33%, 53%, and 56% for patients entering the cohort in 2014, 2015, 2016, and 2017, respectively. For patients entering in 2014, those with current AUD (hazard ratio [HR], 0.72 [95%, CI, 0.66-0.77]) or who were abstinent with an AUD history (HR, 0.91 [95% CI, 0.84-1.00]) were less likely to receive DAA treatment within 1 year compared with patients with lower-risk drinking. For those entering in 2015-2017, patients with current AUD (HR, 0.75 [95% CI, 0.70-0.81]) and those who were abstinent with an AUD history (HR, 0.76 [95% CI, 0.68-0.86]) were less likely to receive DAA treatment within 1 year compared with patients with lower-risk drinking.Conclusions and RelevanceThis cohort study suggests that individuals with AUD, regardless of abstinence, were less likely to receive DAA treatment. Improved access to DAA treatment for persons with AUD is needed.