bluuebunny/crossref_metadata_2025_split huggingface dataset:
Potential efficacy of multipoint pacing in the reduction of mitral regurgitation volume: a case report
Authors: Wada Masato , Kondo Hidekazu , Fukuda Tomoko , Sato Hiroki , Yamasaki Hirochika , Yonezu Keisuke , Uemura Tetsuya , Ogawa Naoko , Saito Shotaro , Shuto Takashi , Wada Tomoyuki , Yufu Kunio , Nobe Seiki , Miyamoto Shinji , Takahashi Naohiko 
Published: April 2022

AbstractA 70‐year‐old woman who had cardiac sarcoidosis and severe tethering mitral regurgitation (MR) and had been implanted with a biventricular pacemaker experienced recurrent hospitalisation due to decompensated heart failure (HF). Application of MultiPoint™ pacing reduced the MR volume and maintained the symptoms under control; however, the predicted longevity of the device significantly decreased because of the very high threshold of the added pacing site. Transcatheter mitral valve repair (TMVR) using MitraClip® was performed to further diminish the severe MR, thereby enabling the switch from highly consumptive multipoint pacing (MPP) to energy‐saving single‐point pacing. MPP could further reduce MR compared to the conventional single‐point pacing, and this could be a bridging therapy to TMVR in some patients implanted with a biventricular pacemaker. This is the first case to report that switching from conventional single‐point pacing to MPP decreased the MR, to some extent, resulting in the improvement of HF symptoms.
Dielectric Response Behavior and Displacement‐Type Metal‐Free Organic‐Inorganic Hybrid Phase Transition Material: trans‐(NH3C6H10NH3)[NO3]2
Authors: Luo Yan , Zhang Yin‐Qiang , Xu Guan‐Cheng 
Published: April 2022

AbstractPhase transition compounds have been attracting interest in scientific research due to their wide applications in dielectric materials. Herein, a new displacement‐type metal‐free organic‐inorganic hybrid phase transition material trans‐(NH3C6H10NH3)[NO3]2 (1) with Tc=245 K has been successfully synthesized. The single‐crystal X‐ray diffraction elucidates that the space group of 1 turns from P
in the high temperature phase to P21/c in the low temperature phase. And the reason of phase transition is related to the displacements of trans‐(NH3C6H10NH3)2+ cations and [NO3]− anions. In addition, 1 shows a dielectric anomaly around the Tc. We expect that this finding will contribute to the research of displacement‐type metal‐free phase transition materials.
A mini review on paraffin‐graphene and related hybrid phase change materials for building energy applications
Authors: Kumar Neeraj , Thapliyal Prakash Chander , Kumar Anuj , Kumar Ashok 
Published: April 2022

AbstractThe thermal energy management in building is gaining the significant attention in the present energy scenario to manage the temperature. Graphene‐related additives are known for their exceptional properties viz. excellent binding and high intrinsic thermal conductivity. The hybrid phase change materials (PCMs) with graphene additives have been applied to enhance the thermal conductivity. Graphene‐related materials are drastically used to improve the properties of PCMs. Incorporating graphene‐related fillers increase the thermal conductivity and preserve the latent heat storage ability of hydrocarbon‐based PCMs. Also, graphene‐related fillers can prevent the leaching properties of the PCMs. These composites can ease concerns regarding energy demand to some level by reversibly storing an incredible quantity of renewable as well as sustainable thermal energy helping to keep up thermal comfort and this has motivated authors to write present mini review. In this review, authors have described PCMs, preparation methods, graphene, graphene oxide, and their composite related PCMs, nanographene added PCMs and their applications in building envelopes utilizing graphene and relative additives.
Scientific research competitiveness in hospitals: A narrative review of major hospital ranking systems in China
Authors: Li Dan , Yu Jing , Lv Zhong‐wei , Gu Wen‐Jun , Li Ji‐yu 
Published: April 2022

AbstractBackground and AimsSeveral hospital ranking systems have been created in China recently, but there is still a lack of comprehensive analysis of the weight and significance of scientific research in hospital ranking. The present study aimed to identify and analyze the role of scientific research competitiveness in various hospital ranking systems in China.MethodsOver 200 materials published between 2010 and 2020 and related to three mainstream hospital ranking systems in China were reviewed. The methodologies applied in the three ranking systems were analyzed and compared. In addition, the comparative learning and analysis of Top 10 and Top 46–55 hospitals according to the ranking system of China's Best Hospital Rankings was performed for a longitudinal study.ResultsThe three major hospital rankings had different scientific research capability ranking methodologies and emphases of scientific research evaluation systems. The most commonly used indicators were science citation index (SCI) publications, National Scientific Foundation of China funding, a number of national key laboratories, and a number of academicians. The relative standing of several top hospitals showed slightly different in the three major Chinese hospital ranking systems. For the longitudinal study, we found that the fluctuation of the ranking of the Top 46–55 hospitals was significantly higher than that of the Top 10 hospitals, in which scientific research played a vital role.ConclusionThe proportion of scientific research plays an important role in the hospital ranking systems. The quality and quantity of SCI publications, the key indicators of national projects, and top academic talents are the most important factors used to evaluate the level of hospital scientific research, and thus affect the ranking of hospitals.
Connectedness between G10 currencies: Searching for the causal structure
Authors: Bettendorf Timo , Heinlein Reinhold 
Published: April 2022

AbstractThis paper presents a new approach for modelling the connectedness between asset returns. We adapt the measure of Diebold and Yilmaz, which is based on the forecast error variance decomposition of a VAR model. However, their connectedness measure hinges on critical assumptions with regard to the variance–covariance matrix of the error terms. We propose to use a more agnostic empirical approach, based on a machine learning algorithm, to identify the contemporaneous structure. In a Monte Carlo study, we compare the different connectedness measures and discuss their advantages and disadvantages. In an empirical application we analyse the connectedness between the G10 currencies. Our results suggest that the US dollar as well as the Norwegian krone are the most independent currencies in our sample. By contrast, the Swiss franc and New Zealand dollar have a negligible impact on other currencies. Moreover, a cluster analysis suggests that the currencies can be divided into three groups, which we classify as: commodity currencies, European currencies and safe haven/carry trade financing currencies.
Adsorptive potential of ZnO/SiO2 nanorods prepared via the sol–gel method for the removal of Pb(II) and Cd(II) from petroleum refinery wastewater
Authors: Shaba Elijah Yanda , Tijani Jimoh Oladejo , Jacob John Olusanya , Suleiman Mohammed Abubakar Tanko 
Published: April 2022

AbstractBACKGROUNDThe adsorption technique is considered one of the most effective and economical methods for the removal of heavy metals, due to its excellent advantages of low cost, high efficiency and easy handling. This research looks into the possibility of using ZnO/SiO2 nanorods to remove Cd(II) and Pb(II) from refinery wastewater and their reusability.RESULTSZnO/SiO2 nanorods were synthesized via the sol–gel method. The analysis of ZnO/SiO2 shows the formation of a rod‐like structure and surface area of 33 m2 g−1 compared with the 0.3 and 8.620 m2 g−1 for ZnO and SiO2, respectively. Effects of adsorption contact time, adsorbent dosage and temperature were examined via batch adsorption. The result indicates that the ZnO/SiO2 rods exhibited higher adsorption removal efficiency of 85.06% and 84.12% for Pb(II) and Cd(II), respectively, compared to Pb(II) (80.00% and 74.25%) and Cd(II) (76.48% and 70.99%) using ZnO and SiO2 nanoparticles. A thermodynamic study indicates that the adsorption process was endothermic. The data from the adsorption isotherm were well fitted to the Langmuir isotherm. The pseudo‐second‐order kinetic model best described the adsorption process. An adsorption–desorption study indicated the adsorption to be concentration‐dependent and maintained up to 80.65% and 76.90% for Pb(II) and Cd(II) after the fourth regeneration cycle.CONCLUSIONSThese findings demonstrated that ZnO/SiO2 nanorods are a better nanoadsorbent for the removal of Pb(II) and Cd(II) than ZnO and SiO2 nanoparticles due to their high adsorptive potential and stability. © 2022 Society of Chemical Industry.
Diagnostic reasoning in rehabilitation nutrition: Position paper by the Japanese Association of Rehabilitation Nutrition (secondary publication)
Authors: Wakabayashi Hidetaka , Maeda Keisuke , Momosaki Ryo , Kokura Yoji , Yoshimura Yoshihiro , Fujiwara Dai , Kosaka Shintaro , Suzuki Norio 
Published: April 2022

AbstractDiagnostic reasoning is the thought process used to arrive at a diagnosis based on symptoms, examination findings, and laboratory values. Diagnosis is categorized as nonanalytic reasoning (intuition) and analytic reasoning (analysis). Rehabilitation nutrition involves the diagnosis of nutritional disorders, sarcopenia, and excess or deficient nutrient intake. There is usually only one correct answer for the presence or absence of these. On the other hand, there may be no single correct answer for the causes of anorexia, weight loss, or sarcopenia, and analytical reasoning is required. In this case, diagnostic reasoning involves hypotheses. Simply using nutritional supplements without performing diagnostic reasoning about these causes is like prescribing antipyretic analgesics to a patient with a headache without diagnosing the cause of the headache. To maximize function and quality of life in rehabilitation nutrition, it is necessary to suspect the common causes of anorexia, weight loss, and sarcopenia in all cases.
Automatic detection, classification, and long‐term investigation of temporal–spatial changes of atmospheric rivers in the Middle East
Authors: Esfandiari Neda , Rezaei Mohammad 
Published: April 2022

AbstractMost water vapour in various subtropical regions is transported by atmospheric rivers (ARs). It is crucial to study this phenomenon, especially in regions more vulnerable to climate change due to population growth and aridity. The study's primary purpose was to detect ARs in the Middle East. According to expectations, ARs were classified based on strength and temporal–spatial distribution and their changes were examined to characterize the risks of the phenomenon. The results showed that ARs had significantly increased over the past 50 years (1971–2020). The most positive increase was related to weak ARs (Cat 1) in the last two decades and exceptional events (Cat 5) in the last decade. The results also indicated the role of terrain in limiting the path of the AR axis and multiple sources of moisture in their strongest form. The occurrence of hazardous events (Cat 4 and 5) was estimated at up to 22% of all ARs in the Middle East, with the highest frequency in the last three decades. It was also found that events with a maximum IVT of >1,000 kg·m−1·s−1 occurred 10 times during the last half of the last century. Also, an AR with a maximum IVT of 1,102 kg·m−1·s−1 occurred once in the region. The temporal distribution of these extreme events showed that they could occur at any time, depending on the conditions of AR formation. However, extreme events mainly occurred in March.
α‐Carotene: a valuable carotenoid in biological and medical research
Authors: Zhao Zilong , Chen Jing , Ci FangFang , Pang He , Cheng Ning , Xing Aijia 
Published: April 2022

Abstractα‐Carotene, one of the C40 carotenes, is a natural lipid‐soluble terpene. The chemical structure of α‐carotene is based on the unsaturated polyene chain skeleton, with an ε‐ring and a β‐ring on each side of the skeleton. α‐Carotene is widely found in dietary fruits and vegetables, and the concentration depends on the plant species. In addition, processing methods and storage conditions used in the food and medical industries can alter the concentration of α‐carotene in raw materials. This review of α‐carotene summarizes the major studies on chemical structure, source, extraction, detection, biosynthesis, processing effect, bioactivity, medicine, and biotechnology. Whether α‐carotene supplementation or a diet rich in fruits and vegetables has a positive effect on the prevention of cancer, cardiovascular disease, and other diseases is the focus of this study. © 2022 Society of Chemical Industry.
All inkjet‐printed 6.95″ 217 ppi active matrix QD‐LED display with RGB Cd‐free QDs in the top‐emission device structure
Authors: Park Myoungjin , Kim Young Il , Jung Yun Ku , Kang Jin‐goo , Kim Sehun , Ha Jaekook , Yoon Yeo‐geon , Lee Changhee 
Published: April 2022

AbstractElectroluminescence quantum dot devices (QD‐LEDs) show the promise in the development of future displays. For commercialization, the top emission device structure is more advantageous than the bottom emission device structure to realize the high aperture ratio full color displays. Moreover, it is essential to understand not only the device structure and characteristics of QD‐LEDs but also the challenging issues in inkjet‐printed devices. Here, we demonstrated the world first all inkjet‐printed Cd‐free active matrix QD‐LEDs based on getting over the hurdles of all inkjet printing process. Especially, we have fabricated QD‐LED devices by stacking 4‐soluble layers without intermixing and studied the factors affecting QD efficiency and QD printing and the influence of ETL solvent on QD. Inkjet‐printed QD‐LED devices have achieved 8 cd/A, 70 cd/A, and 8 cd/A current efficiency of red, green, and blue, respectively, on the basis of 250 nits of full white RGB panels. We believe that our work clarifies an encouraging step toward the practical application of Cd‐free based QD‐LED displays.
Molecular pathogenesis and emerging targets of gastric adenocarcinoma
Authors: Ivey Abby , Pratt Hillary , Boone  Brian A. 
Published: April 2022

AbstractGastric adenocarcinoma (GC) is a devastating disease and is the third leading cause of cancer deaths worldwide. This heterogeneous disease has several different classification systems that consider histological appearance and genomic alterations. Understanding the etiology of GC, including infection, hereditary conditions, and environmental factors, is of particular importance and is discussed in this review. To improve survival in GC, we also must improve our therapeutic strategies. Here, we discuss new targets that warrant further exploration.
Current and future imaging modalities in gastric cancer
Authors: Tham Elwin , Sestito Michael , Markovich Brian , Garland‐Kledzik Mary 
Published: April 2022

AbstractGastric adenocarcinoma treatment can include endoscopic mucosal resection, surgery, chemotherapy, radiation, and palliative measures depending on staging. Both invasive and noninvasive staging techniques have been used to dictate the best treatment pathway. Here, we review the current imaging modalities used in gastric cancer as well as novel techniques to accurately stage and screen these patients.
Is increasing nodal count associated with improved recurrence‐free and overall survival following standard right hemicolectomy for colon cancer?
Authors: Hayes Ian P. , Milanzi Elasma , Gibbs Peter , Faragher Ian , Reece Jeanette C. 
Published: April 2022

AbstractBackground and ObjectivesIncreasing lymph node harvest for right‐sided colon cancer is associated with improved overall survival (OS), but most relevant studies failed to report the extent of resection. We examined the association between increasing lymph node count with standard right hemicolectomy according to nodal status and prognostic outcomes in right‐sided tumors.MethodsRetrospective analysis of prospectively collected clinical data from patients with proximal colonic adenocarcinomas (n = 1390) following right hemicolectomy. Associations between lymph node counts (0–12 vs. 13–15, 16–20, and >20) and recurrence‐free survival (RFS) and OS were examined using multivariate Cox modeling adjusted for confounders.ResultsWe found no association between increasing nodal count and RFS, regardless of nodal status. In the absence of nodal metastases, increasing nodal count (16–20 and >20 vs. 0–12 nodes) was associated with 57% (95% confidence interval [CI]: 0.21–0.89) and 52% (95% CI: 0.24–0.95) improved OS, respectively. In the presence of nodal metastases, increasing nodal count was not associated with OS. Adjuvant chemotherapy did not modify this effect.ConclusionIncreasing nodal count (>15 nodes) with right hemicolectomy was not associated with improved RFS. Improved OS was only found for node‐negative tumors, casting some doubt on the benefits of resecting more lymph nodes in the presence of nodal metastases.
The Value of IOTA Simple Rules Combined With CEUS Scoring System in the Diagnosis of Benign and Malignant Ovarian Masses and Its Correlation With MVD and VEGF: A Preliminary Study
Authors: Liu Chun , Li Yuan , Zhu Yi , Lu Man 
Published: April 2022

ObjectivesTo investigate the diagnostic value of International Ovarian Tumor Analysis (IOTA) simple rules combined with contrast‐enhanced ultrasound (CEUS) scoring system in the differential diagnosis of ovarian tumors, and the correlations of the scoring system with microvessel density (MVD) and vascular endothelial growth factor (VEGF).MethodsOne hundred eighty‐nine patients with ovarian tumors were examined by routine ultrasound and CEUS. The enhanced characteristics of CEUS were observed, and the masses were classified by IOTA simple rules. To compare the diagnostic value of IOTA simple rules combined with CEUS scoring system and IOTA simple rules in the diagnosis of ovarian tumors. Immunohistochemistry was used to detect the expression of MVD and VEGF in postoperative tissue samples. The correlations between the new scoring system with MVD and VEGF were analyzed.ResultsThe sensitivity (93.98%), specificity (94.34%), positive predictive value (92.86%), negative predictive value (95.24%), and accuracy (94.18%) of IOTA simple rules combined with CEUS scoring system in the diagnosis of ovarian tumors were higher than those of IOTA simple rules alone (all P < .05). The score system was significantly positively correlated with MVD and VEGF, and the r values were 0.77 and 0.63, respectively (P < .001).ConclusionsIOTA simple rules combined with CEUS scoring system was helpful to improve the accuracy of ultrasound diagnosis of ovarian tumors, which was significantly correlated with MVD and VEGF. It could provide important reference information for treatment scheme formulation and prognosis evaluation.
Preparation of AIE Functional Single‐Chain Polymer Nanoparticles and Their Application in H2O2 Detection through Intermolecular Heavy‐Atom Effect
Authors: Lu Zhimin , Zhang Junyong , Yin Wang , Guo Changfa , Lang Meidong 
Published: April 2022

AbstractSingle‐chain polymer nanoparticles (SCNPs) are soft matter constructed by intrachain crosslinks, with promising prospects in detection and catalysis. Herein, a fluorescent core (SCNPs) with aggregation‐induced emission (AIE) is prepared, applying for H2O2 detection through intermolecular heavy‐atom effect. In detail, the SCNPs precursors are synthesized by ring‐opening copolymerization. Then the SCNPs are prepared by intramolecularly cross‐linking via olefin metathesis. Imitating the structure of AIE dots, SCNPs are encapsulated by H2O2‐responsive polymers. Probably due to the stable secondary structure of SCNPs, the obtained micelles show stable fluorescence performance. Furthermore, as the heavy‐atom, tellurium is introduced into the carriers to construct the heavy‐atom effect. In this micelle‐based system, the SCNPs act as the fluorescent core, and the stimuli‐responsive polymer acts as the carrier and the fluorescent switch. The hydrophilicity of the tellurium‐containing segment is affected by the concentration of H2O2, resulting in a change in the distance from the SCNPs, which ultimately leads to a change in the fluorescence intensity. Furthermore, tellurium is particularly sensitive to H2O2, which can detect low concentrations of H2O2. The SCNPs are merged with AIE materials, with the hope of exploring new probe designs.
Antenna characterization based on backscattered electromagnetic waves
Authors: Sekhri Yacine , Grassin Patricia , Gaoua Malik , Gadot Frederique , Ouslimani Habiba Hafdallah 
Published: April 2022

AbstractThis paper proposes a Radar technique to reconstruct the intrinsic properties of antennas. The study presents the measurements and CST MWS simulations of the backscattered wave and Radar Cross Section (RCS) of two target‐antennas over a wide frequency range (1−8 GHz). A calibration process based on standard metal targets with well‐known RCS values, combined to a gating–time filter is used to extract the reradiate antenna mode with good accuracy. Based on a linear quadrupole model, the antenna transmission parameters are connected to the reradiate antenna mode and the system of equations is solved with several sets of measurements or simulations using multiple terminal load impedances. The antenna, gain and reflection coefficient both measured and simulated are reconstructed with the Radar technique and are compared to the results of conventional measurements and CST MWS simulations. The method is simple in its implementation and has proven to be effective.
Free‐breathing self‐gated continuous‐IR spiral T1 mapping: Comparison of dual flip‐angle and Bloch‐Siegert B1‐corrected techniques
Authors: Zhou Ruixi , Wang Junyu , Weller Daniel S. , Yang Yang , Mugler John P. , Salerno Michael 
Published: April 2022

PurposeTo develop a B1‐corrrected single flip‐angle continuous acquisition strategy with free‐breathing and cardiac self‐gating for spiral T1 mapping, and compare it to a previous dual flip‐angle technique.MethodsData were continuously acquired using a spiral‐out trajectory, rotated by the golden angle in time. During the first 2 s, off‐resonance Fermi RF pulses were applied to generate a Bloch‐Siegert shift B1 map, and the subsequent data were acquired with an inversion RF pulse applied every 4 s to create a T1* map. The final T1 map was generated from the B1 and the T1* maps by using a look‐up table that accounted for slice profile effects, yielding more accurate T1 values. T1 values were compared to those from inversion recovery (IR) spin echo (phantom only), MOLLI, SAturation‐recovery single‐SHot Acquisition (SASHA), and previously proposed dual flip‐angle results. This strategy was evaluated in a phantom and 25 human subjects.ResultsThe proposed technique showed good agreement with IR spin‐echo results in the phantom experiment. For in‐vivo studies, the proposed technique and the previously proposed dual flip‐angle method were more similar to SASHA results than to MOLLI results.ConclusionsB1‐corrected single flip‐angle T1 mapping successfully acquired B1 and T1 maps in a free‐breathing, continuous‐IR spiral acquisition, providing a method with improved accuracy to measure T1 using a continuous Look‐Locker acquisition, as compared to the previously proposed dual excitation flip‐angle technique.