bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phyllosphere bacterial and fungal communities vary with host species identity, plant traits and seasonality in a subtropical forest
Authors: Li Mengjiao , Hong Lan , Ye Wanhui , Wang Zhangming , Shen Hao 
Published: June 2022

AbstractBackgroundPhyllosphere microbes play important roles in host plant performance and fitness. Recent studies have suggested that tropical and temperate forests harbor diverse phyllosphere bacterial and fungal communities and their assembly is driven by host species identity and plant traits. However, no study has yet examined how seasonality (e.g. dry vs. wet seasons) influences phyllosphere microbial community assembly in natural forests. In addition, in subtropical forests characterized as the transitional zonal vegetation type from tropical to temperate forests, how tree phyllosphere microbial communities are assembled remains unknown. In this study, we quantified bacterial and fungal community structure and diversity on the leaves of 45 tree species with varying phylogenetic identities and importance values within a 20-ha lower subtropical evergreen broad-leaved forest plot in dry and wet seasons. We explored if and how the microbial community assembly varies with host species identity, plant traits and seasonality.ResultsPhyllosphere microbial communities in the subtropical forest are more abundant and diverse than those in tropical and temperate forests, and the tree species share a “core microbiome” in either bacteria or fungi. Variations in phyllosphere bacterial and fungal community assembly are explained more by host species identity than by seasonality. There is a strong clustering of the phyllosphere microbial assemblage amongst trees by seasonality, and the seasonality effects are more pronounced on bacterial than fungal community assembly. Host traits have different effects on community compositions and diversities of both bacteria and fungi, and among them calcium concentration and importance value are the most powerful explaining variables for bacteria and fungi, respectively. There are significant evolutionary associations between host species and phyllosphere microbiome.ConclusionsOur results suggest that subtropical tree phyllosphere microbial communities vary with host species identity, plant traits and seasonality. Host species identity, compared to seasonality, has greater effects on phyllosphere microbial community assembly, and such effects differ between bacterial and fungal communities. These findings advance our understanding of the patterns and drivers of phyllosphere microbial community assembly in zonal forests at a global scale.
Killing underweighted low viable newborn piglets: Which health parameters are appropriate to make a decision?
Authors: Geiping Lukas , Hartmann Maria , Kreienbrock Lothar , grosse Beilage Elisabeth 
Published: June 2022

AbstractBackgroundThe aim of this study was to estimate the mortality risk and associated factors within the first days of life for underweight or low-vital neonatal piglets. This risk estimation should start a discussion concerning the preconditions for timely killing of compromised newborn piglets to prevent unnecessary pain and suffering. In an observational study, various clinical and laboratory variables were examined in 529 piglets out of four farms. Body weight, crown-rump-length, rectal temperature, a 4-stage vitality score, an intrauterine-growth-retardation score, glucose, lactate, haemoglobin and immunocrit were assessed on the first day of life. Vitality was scored by three factors: movement, abdominal palpation, and colour of the skin. Afterwards the death of the piglets (by killing or spontaneously) was monitored until day 5 of age.ResultsBody weight, rectal temperature and vitality score were significantly associated with probability of death. Piglets with rectal temperatures ≤ 37.5 °C, a body weight < 0.86 kg and impaired vitality scores were found to have the highest probability of death until day 5 of age.ConclusionThe clinical findings, identified by this model, allow a first estimation of mortality risk for newborn piglets within the first days of life. In a further step veterinarians, farmers and ethicians now need to clarify what probability of death should justifiy the killing of a newborn piglet.
A case study of the impact of a teacher education course on two Iranian EFL teachers’ beliefs and practices about grammar teaching
Authors: Nazari Mostafa , Boustani Azadeh , Sheikhi Mohammad 
Published: June 2022

AbstractDespite the substantial growth of research on teachers’ beliefs and practices in the past decades, little research has examined the impact of teacher education on in-service teachers’ grammar beliefs and practices. The present study aimed to fill part of this gap in relation to two Iranian novice EFL teachers. Data were collected before and after a grammar-oriented teacher education course from semi-structured interviews and classroom observations. The findings showed that the course influenced the teachers’ beliefs to move from a more teacher-fronted approach toward an approach that marked attention to the importance of learners’ socioemotional states. Moreover, the teachers’ practices after the course featured more attention to the collaborative and pragmatic aspects of grammar instruction. Based on the findings, we provide several implications for teacher education, which highlight the role of sociocultural and personal dimensions in programs that are structured around grammar instruction.
Consequences of COVID-19 pandemics on the mental well-being of general population of Pakistan
Authors: Um-e-Kalsoom  , Bibi Nadia 
Published: June 2022

Abstract
Background
Due to the COVID-19 outbreak, the epicenter is facing transcending psychiatric problems.
To assess the consequences of the COVID-19 pandemic on the mental well-being of the community of Peshawar, Khyber Pakhtunkhwa (Pakistan), a cross-sectional study design was used to find out depression and anxiety after the first wave of the pandemic. A total of 320 willing individuals participated in the study. Convenience sampling technique was used to collect the data. Demographic information along with a semi-structured interview, Hospital Anxiety and Depression Scale, Impact of Life Event Scale-Revised, and Center of Epidemiologic Studies-Depression Scale were used as measures. The participants of this study were bifurcated into affected (n = 151) and none affected (n = 169) on the basis of the impact of life event cut-off scores.

Results
Data analysis was carried out using t-test and simple linear regression analysis. Results of t-test showed that the pandemic-affected individuals (47%) reported significantly high on the depression and anxiety scores. The verdicts from simple linear regression analysis further demonstrate a history of psychiatric illness, duration of quarantine, and impact of event predicting depression (R2 = .15, p < .001). For anxiety history of psychiatric illness, the impact of life events were significant predictors (R2 = .28, p < .001) whereas the duration of quarantine, death due to COVID-19, and Impact of Event Scale predicted the center of epidemiological studies for depression (R2 .48, p < .001). The finding of the research study concluded that 47% participated individuals were affected due to the pandemic COVID-19.

Conclusions
The outcome of the study further exhibits that history of previous psychiatric illness, impact of life events, death due to COVID-19, and duration of quarantine are significant predictors of depression and anxiety.
Fluid Biomarkers in Dementia Diagnosis
Authors: Schindler Suzanne E. 
Published: June 2022

ABSTRACT

PURPOSE OF REVIEW
This article discusses how fluid biomarkers can augment the routine dementia evaluation and improve diagnostic accuracy. The tests that are currently available and the indications for their use are described. Further, tests that are under development and likely to be used in the future are identified.

RECENT FINDINGS
Technical improvements in assay sensitivity and precision have led to the rapid development of blood-based biomarkers for Alzheimer disease (AD) over the past several years. Studies have found that the ratio of amyloid-β (Aβ) peptides (Aβ42/Aβ40) and concentrations of phosphorylated tau isoforms in plasma can identify individuals with AD brain pathology. Blood-based tests may enable much broader use of AD biomarkers in the evaluation of patients with cognitive impairment.

SUMMARY
Even after a detailed history, examination, routine laboratory testing, and brain imaging, the cause of dementia sometimes remains unclear. CSF and blood-based biomarkers can evaluate for a range of neurologic disorders that are associated with dementia, including AD. Integrating data from fluid biomarker tests and the routine dementia evaluation may improve the accuracy of dementia diagnosis.
Vascular Cognitive Impairment and Dementia
Authors: Chang Wong Ellen , Chang Chui Helena 
Published: June 2022

ABSTRACT

PURPOSE OF REVIEW
This article gives a broad overview of vascular cognitive impairment and dementia, including epidemiology, pathophysiology, clinical approach, and management. Emphasis is placed on understanding the common underlying types of cerebrovascular disease (including atherosclerosis, arteriolosclerosis, and cerebral amyloid angiopathy) and awareness of rare inherited cerebrovascular disorders.

RECENT FINDINGS
The pathophysiology of vascular cognitive impairment and dementia is heterogeneous, and the most recent diagnostic criteria for vascular cognitive impairment and dementia break down the diagnosis of major vascular dementia into four phenotypic categories, including subcortical ischemic vascular dementia, poststroke dementia, multi-infarct dementia, and mixed dementia. Control of cardiovascular risk factors, including management of midlife blood pressure, cholesterol, and blood sugars, remains the mainstay of prevention for vascular cognitive impairment and dementia. Cerebral amyloid angiopathy requires special consideration when it comes to risk factor management given the increased risk of spontaneous intracerebral hemorrhage. Recent trials suggest some improvement in global cognitive function in patients with vascular cognitive impairment and dementia with targeted cognitive rehabilitation.

SUMMARY
Thorough clinical evaluation and neuroimaging form the basis for diagnosis. As vascular cognitive impairment and dementia is the leading nondegenerative cause of dementia, identifying risk factors and optimizing their management is paramount. Once vascular brain injury has occurred, symptomatic management should be offered and secondary prevention pursued.
Object Orientations and Circulatory Form in Abdulrazak Gurnah’sBy the Sea
Authors: Cooppan Vilashini 
Published: June 2022

AbstractThe circulatory connectivity that defines the Indian Ocean as critical object also inheres in objects themselves and the descriptive economies surrounding them. Combining regional chronotopes, the thingly imaginary of Abdulrazak Gurnah’s novel By the Sea, Graham Harman’s object-oriented ontology, and world literature, this essay explores how a close encounter with objects, stories, and descriptive language can reveal the form and poetics of the Indian Ocean. A concept of regional relationality, encompassing both connectivity and narratability, emerges alongside the liquid reading of Indian Ocean fluidities. Linking descriptive chronotopes of the region to By the Sea’s object worlds and the words that carry them, the essay links a single instance of Indian Ocean literature to larger speculation about the regional object itself. Tracking flows of space, time, memory, affect, description, and narration as they cut across the novel and the region, the author pursues the hermeneutic possibilities of a notion of circulatory form.
Under the Sign of Ariel: Disputed Territories, Rising Tides, and Literary Mauritius
Authors: Lionnet Françoise 
Published: June 2022

Abstract
The continued strategic importance of the Indian Ocean has led to contests over the sovereignty and integrity of its islands and territorial waters. Francophone Mauritian writers have been vocal about a situation they have denounced as unacceptable. Their literary engagement with our fragile planet and its species offers strong aesthetic responses to urgent political impasses. Ananda Devi’s eponymous character Joséphin entertains a relation with the Indian Ocean that can be read as a layered parable of the end of man. Her novel is a brilliant poetic translation of Michel Foucault’s view of history careening toward the vanishing point of the human as well as a powerful echo of traditional Hindu cultural beliefs about the continuum between human and animal life-forms, about rebirth and regeneration. For Édouard Maunick, the island itself is the site of a creative beginning, where new forms of culture and identity are created in the crucibles of colonization and creolization. For Marie-Thérèse Humbert, ocean waves are the ambivalent vector of a rebirth that returns the island and its occupants—human, animal, vegetal and elemental—to a utopian state of uneasy equilibrium beyond the lies and vagaries of neocolonial dispossession.
Changes in the utilisation of acute hospital care in Ireland during the first wave of the COVID-19 pandemic in 2020
Authors: Marron Louise , Burke Sara , Kavanagh Paul 
Published: June 2022

Background: Reduced and delayed presentations for non-COVID-19 illness during the COVID-19 pandemic have implications for population health and health systems. The aim of this study is to quantify and characterise changes in acute hospital healthcare utilisation in Ireland during the first wave of COVID-19 to inform healthcare system planning and recovery. Methods: A retrospective, population-based, observational study was conducted using two national datasets, Patient Experience Time (PET) and Hospital In-Patient Enquiry (HIPE). The study period was 6th January to 5th July 2020. Results: Comparison between time periods pre- and post-onset of the COVID-19 pandemic within 2020 showed there were 81,712 fewer Emergency Department (ED) presentations (-18.8%), 19,692 fewer admissions from ED (-17.4%) and 210,357 fewer non-COVID-19 hospital admissions (-35.0%) than expected based on pre-COVID-19 activity. Reductions were greatest at the peak of population-level restrictions, at extremes of age and for elective admissions. In the period immediately following the first wave, acute hospital healthcare utilisation remained below pre-COVID-19 levels, however, there were increases in emergency alcohol-related admissions (Rate Ratio 1.22, 95% CI 1.03, 1.43, p-value 0.016), admissions with self-harm (Rate Ratio 1.39, 95% CI 1.01, 1.91, p-value 0.043) and mental health admissions (Rate Ratio 1.28, 95% CI 1.03, 1.60, p-value 0.028). Discussion: While public health implications of delayed and lost care will only become fully apparent over time, recovery planning must begin immediately. In the short-term, backlogs in care need to be managed and population health impacts of COVID-19 and associated restrictions, particularly in relation to mental health and alcohol, need to be addressed through strong public health and health system responses. In the long-term, COVID-19 highlights health system weakness and is an opportunity to progress health system reform to deliver a universal, high-quality, sustainable and resilient health system, capable of meeting population health needs and responding to future pandemics.
Implementation of telemedicine consultations for people with mental health conditions in the community: a protocol for a systematic review
Authors: Galvin Emer , Desselle Shane , Gavin Blánaid , Quigley Etain , Flear Mark , Kilbride Ken , McNicholas Fiona , Cullinan Shane , Hayden John 
Published: June 2022

Background: The COVID-19 pandemic response has led to an exponential increase in the use and spread of telemedicine internationally. In community mental health care settings, telemedicine services were implemented within a few weeks, with little time for rigorous planning. Despite the reported acceptability of telemedicine by patients and clinicians, barriers to its implementation have come to light. There is now a need to investigate these barriers, and facilitators, as telemedicine begins to show potential promise beyond the pandemic. We propose a review that aims to identify the factors affecting the implementation of telemedicine consultations for patients with mental health conditions in the community. Methods: A systematic review will be conducted and reported according to the PRISMA guidelines. Five electronic databases will be searched using a pre-defined search strategy from 2016 to 2021. Only studies of synchronous, interactive telemedicine consultations conducted via video, phone or live messaging between patients and providers will be included. Quantitative, qualitative and mixed methods studies will be eligible for inclusion. Only studies published in the English language will be included. Titles and abstracts will be screened by two reviewers. Full text articles will be screened by two reviewers. The methodological quality of studies will be assessed using the Mixed Method Appraisal Tool (MMAT) by two reviewers. Data will be extracted and tabulated to address the aims of the review. A narrative synthesis will be conducted and reported factors will be mapped to the domains of the Consolidated Framework for Implementation Research (CFIR). Conclusion: By identifying the factors that influence the implementation of telemedicine consultations for patients with mental conditions in the community, consideration can be given to both barriers and facilitators that could be addressed in future mental health services planning. PROSPERO registration: CRD42021273422 (04/10/2021)
Older adults identified as frail by Frailty Index and FRAIL scale who were intensively treated for hypertension were at increased risk of 2-year adverse health outcomes in The Irish Longitudinal Study on Ageing (TILDA)
Authors: O'Donoghue Patrick , O'Halloran Aisling , Kenny Rose Anne , Romero-Ortuno Roman 
Published: June 2022

Background: Frailty is associated with adverse health outcomes. In frail older adults, blood pressure (BP) treated intensively may result in side effects including orthostatic hypotension, falls or fractures. We hypothesised that frail older adults, with BP treated below the threshold of the 2018 European Society of Cardiology/European Society of Hypertension (ESC/ESH) guideline (<130/70 mmHg), could be associated with adverse health outcomes. Methods: Data was gathered from participants in Wave 1 (W1) of The Irish Longitudinal Study on Ageing (TILDA) who were aged ≥65 years and on treatment for hypertension. Frail classifications as per a 32-item Frailty Index (FI) and FRAIL (Fatigue, Resistance, Ambulation, Illnesses & Loss of Weight) scale were compared in their ability to predict W2 (2-year) adverse outcomes associated with intensive BP control (‘low’: <130/70 mmHg vs. ‘high’: ≥130/70 mmHg). We created eight participant groups based on frailty-BP status. W2 outcomes were analysed using adjusted binary logistic regression models. Results: In W1, 1,920 participants were included. Of these 1,274 had complete FI-BP and 1,276 FRAIL-BP data. The frail by FI treated low and frail by FRAIL treated low had increased risk of hospitalisation, heart failure and falls/fracture by W2. The frail by FRAIL treated low also had increased risk of mortality by W2. The frail by FI treated high had increased risk of syncope and falls/fractures. The non-frail by FI or FRAIL did not have increased risk of any of the adverse outcomes studied. Conclusions: FI and FRAIL captured increased risk of adverse health outcomes when BP was treated below the current ESC/ESH threshold. FI and FRAIL could be more useful than other frailty identification tools to signal risks associated with tighter BP control in frail older adults. Hypertension management guidelines should specify which frailty identification tools clinicians should use to help them make personalised treatment decisions.
Multivariable prediction models for long-term outcomes after hip fracture: A protocol for a systematic review
Authors: Walsh Mary E. , Kristensen Pia Kjær , Hjelholt Thomas J. , Hurson Conor , Walsh Cathal , Blake Catherine 
Published: June 2022

Background: Hip fracture results in high mortality and, for many survivors, long-term functional limitations. Multivariable prediction models for hip fracture outcomes have the potential to aid clinical-decision making as well as risk-adjustment in national audits of care. The aim of this study is to identify, critically appraise and synthesise published multivariable prediction models for long-term outcomes after hip fracture. Protocol: The systematic review will include a literature search of electronic databases (MEDLINE, Embase, Scopus, Web of Science and CINAHL) for journal articles. Search terms related to hip fracture, prognosis and outcomes will be included. Study selection criteria includes studies of people with hip fracture where the study aimed to predict one or more long-term outcomes through derivation or validation of a multivariable prediction model. Studies will be excluded if they focus only on the predictive value of individual factors, or only include patients with periprosthetic fractures, fractures managed non-surgically or younger patients. Covidence software will be used for data management. Two review authors will independently conduct study selection, data extraction and appraisal. Data will be extracted based on the Critical Appraisal and Data Extraction for Systematic Reviews of Prediction Modelling Studies (CHARMS) checklist. Risk of bias assessment will be conducted using the Prediction model Risk of Bias Assessment Tool (PROBAST). Characteristics and results of all studies will be narratively synthesised and presented in tables. Where the same model has been validated in multiple studies, a meta-analysis of discrimination and calibration will be conducted. Conclusions: This systematic review will aim to identify multivariable models for hip fracture outcome prognosis that have been derived using high quality methods. Results will highlight if current models have the potential for further assessment for use in both clinical decision making and improving methods of national hip fracture audits. PROSPERO registration: CRD42022330019 (25th May 2022).