bluuebunny/crossref_metadata_2025_split huggingface dataset:
How do organisations generate and distribute value? Stakeholder value as the aim of the New Business Narrative [NBN] and Stakeholder Accounting [SA] as an information tool
Authors: Retolaza Ávalos José Luis , San-Jose Leire , Freeman R. Edward 
Published: April 2022

Many different companies have decisively embraced the New Business Narrative focused on the Stakeholder Theory and it has been part of the ethos of leading companies worldwide for some time now. However, a systematic process has not been developed to identify an organisation’s withdrawn or distributed value for its different stakeholders in monetary terms. Accounting is inadequate for this purpose and the current information system therefore needs to be expanded. This article reflects on Stakeholder Accounting [SA]. Based on the multi-faceted model, it proposes broadening the value concept to also include price-based transactions, transfers performed in a non-market environment (and without consideration), and emotional ones. Moreover, it proposes expanding from a one-dimensional perspective, focused on shareholders, to a multi-dimensional including all the stakeholders of the organisation. The rest of the article reflects on the multiple experiences generated over the last ten years, along with the applicability, the potential and the implications of this accounting both for organisations and for their stakeholders.
Received: 11 November 2021Accepted: 18 February 2022
Sostenibilidad : clarificaciones para esta “década de la acción”
Authors: Zicari Adrian Pablo 
Published: April 2022

En estos últimos tiempos ha habido un cambio gradual, una mayor aceptación, hacia la sostenibilidad, tanto en medios académicos como empresarios. Sin embargo, al mismo tiempo, se puede también percibir una cierta confusión frente a la multiplicación de iniciativas, estándares y siglas. Además, varios debates se superponen, abogando por diferentes consideraciones ambientales y sociales, a veces contrapuestas entre sí. El objetivo pues de esta nota es brindar algunas clarificaciones, que ayudarán a los lectores a comprender mejor esta “década de la acción”, tal cual la ha llamado las Naciones Unidas. Propongo entonces siete cuestiones, que analizaré sucesivamente. Estas cuestiones no son exhaustivas, seguramente habrá otras cuestiones relevantes. Pero son ciertamente temáticas centrales, que podemos suponer que continuarán siendo cruciales en los próximos años.
Recibido: 18 noviembre 2021Aceptado: 7 febrero 2022
De la teoría a la práctica: ¿cómo se forman líderes empresariales con valores? Lecciones desde la inspiración ignaciana
Authors: Guibert Ucín José María 
Published: April 2022

No basta con tener teorías sobre qué es un buen liderazgo o qué características queremos que tenga una persona líder. Hay que buscar evidencia sobre modelos exitosos de desarrollo de liderazgo. Muchas investigaciones analizan la influencia de lo religioso en el liderazgo, que une el desarrollo moral y espiritual. Esto se nota en áreas como la toma de decisiones, la gestión de personas, la definición de la misión de la organización, la responsabilidad social hacia los distintos afectados, el sentido del trabajo y búsqueda de significado, el cuidado en el desarrollo de carreras profesionales, etc. Siguiendo ejemplos relacionados con la Compañía de Jesús, un ejemplo de un modelo de desarrollo de liderazgo unido a formación en valores debería tener un planteamiento holístico que tiene en cuenta varios pasos: planificación personalizada, experiencias y pruebas, reflexión, evaluación, formación y lecturas, acompañamiento y tutorización.
Recibido: 21 junio 2021Aceptado: 25 enero 2022
Biodynamic and ecology of Human enteropathogenic Microsporidian spores in groundwater in the municipalities of Mbankomo and Soa in Center Region (Cameroon) and health risks of immunocompromised patient
Authors: Atud Asi Quiggle , Aghaindum Ajeagah Gideon , Pulcherie Ngakomo Ananga Rose , Mama Mbouombouo , Nadège Okoa Amougou Thérèse 
Published: April 2022

Abstract
In order to assess the biodynamic and environmental factors of Human enteropathogenic Microsporidia spores present in the groundwater in Mbankomo and Soa municipalities (Center region of Cameroon), a study was carried out on a sample of eight (8) wells and eight ( 8) springs regularly used by the population, from August 2018 to August 2019. The physico-chemical analysis was carried out both in the fields and at the Hydrobiology and Environment laboratory of the University of Yaoundé I. The microsporidian spores observation were made at the 100X objective based on the use of Weber's technique. The physico-chemical parameters show that these waters are slightly acid (6.21 ± 0.09 US) with high values of turbidity ​​ (24.88 ± 16.09 FTU). The biological analysis showed variations in shapes within the same species and between species on one hand and identical forms between species on the other hand. In this study, two microsporidian species were characterized with average densities of 193 ± 93 spores/L (45%) and 227 ± 127 spores/L (55%) for Enterocytozoon bieneusi ([1 - 1.6] x [0.7 - 1.2])µm, and Encephalitozoon intestinalis ([1.8 - 2.4 x [1.2-2.0]) µm respectively. Statistical analysis showed significant and positive correlations between the densities of spores and dissolved oxygen (P ˂ 0.05). The Mann-Whitney test revealed significant differences in microsporidian spores densities seasonally with great values on the short rainy season. Furthermore, this study shows that the consumption of untreated water from wells and springs is of health risks and prove the important of Microsporidia to monitor the quality of drinking water.
Development of an Autonomous Vision Sensor-Actuator-Based Circumferential Seam Path Tracker Welding Machine for LPG Cylinders
Authors: Kumar Kartik , Mishra Ruby , Gour Surjeet Singh , PANDEY ANISH 
Published: April 2022

Abstract
This paper presents an autonomous vision sensor-actuator-based circumferential seam path tracker welding machine for LPG (Liquefied Petroleum Gas) cylinders. The machine is designed to avoid various hazardous health issues that are found on the workers due to unfavorable working conditions during the welding process because of high temperature, dangerous fumes, and a large amount of luminous flux in the workstation. This machine involves a pneumatic holder to hold the cylindrical workpiece inside a metallic body frame. When the cylindrical workpiece rotates in a pneumatic holder, some amount of deflection arises due to the improper arrangement of fixtures and cylinders. It is not easy to overcome this deflection in fixtures, and due to this, the welding process is not done correctly. The undercut and overcut errors can also be found due to the improper shape of fixtures and cylinders. Therefore, the box setup is designed to cope with this problem, and the box contains an RGB (Red Green Blue) camera, LED (Light Emitting Diode), and ultrasonic sensor. The box is installed in front of the welding torch to capture the image of the seam path of the workpiece. Firstly, the image is created with the help of a LED fitted inside the box. The LED creates the shadow of the jobber joint of the cylindrical workpiece. The camera captures that shadow. After capturing the image of shadow, the centroid of the seam path (represented by shadow) of the cylindrical workpiece is traced. It is sent to the Raspberry Pi microcontroller for further processing. According to the position of the centroid coordinate, the microcontroller sends the control commands to the microstep driver of the stepper motor to follow this centroid coordinate, and the torch is controlled and the welding process is done autonomously. The experimental setup is made, and the autonomous welding process is performed in many cylinders. The successful welding results verify the effectiveness and efficiency of the developed machine.
Incidence of graft-versus-host-disease in Germany – evidence from health care claims data
Authors: Scheid Christof , Kudernatsch Robert , Eckart Marie , Libutzki Berit , Feig Chiara , Mahlich Jorg C 
Published: April 2022

Abstract
Introduction
Graft-versus-host disease (GvHD) can occur as an immunological response after an allogeneic hematopoietic cell transplantation (allo-HCT). Due to the rarity of the disease German epidemiological data are scarce. Moreover, not all cases of GvHD are properly documented in daily practice. Against this background, this study aims at providing new estimates on the incidence of GvHD in Germany.
Methods
Based on a large German claims database, a retrospective longitudinal analysis was conducted over a six-year period. Patients were selected that received allo- HCT between 2014 and 2015. Follow up period was three years. To adjust the incidence for undocumented cases, steroid prescriptions after an allo-HCT was used as an approximation. Based on both documented and undocumented GvHD patients, incidence rates were calculated.
Results
Among 3,737,317 eligible database enrollees, we identified 297 patients who received an allo-HCT between 2014 and 2015. Depending on the extrapolation method, this corresponds to a yearly incidence of 2,760-3,246 in Germany. 134 of the 297 patients (i.e. 45.1%) developed a documented GvHD within three years after the transplantation which translates into a yearly incidence of 1,278–1,419 GvHD patients. Based on the medication regimens, we identified 83 additional patients with an suspected GvHD without a documented diagnosis. Extrapolated to the German population, our estimates suggests that the annual incidence of GvHD including undocumented cases could be as high as 2,069 − 2,298 which is higher than previously reported.
Conclusion
More patients may be affected by GvHD in Germany than reported. Appropriate adjustments need to be made when utilizing administrative data.
Role of Education and resource benefit can affect people perception towards the largest freshwater lake of Odisha, India
Authors: DASH SURAJ KUMAR , Payra Arajush , Sonker Gaurav , Palei Himanshu Shekhar , Mishra Arun Kumar , Mishra Rabindra Kumar 
Published: April 2022

Abstract
Ansupa is the largest freshwater lake of Odisha that is significant for its biodiversity and provisioning services. In the light of its wide range of social and economic benefits and many effects on human wellbeing the present communication attempts to determine local stakeholder’s dependency or resource use, knowledge, and perception towards this wetland. The survey found that people living on the fringes of the lake are either directly or indirectly dependent on it, regardless of their caste or economic status, and that nearly 40% of the respondents rely completely on the lake for their livelihoods. Irrigation, pisciculture, non-timber forest products, and fodder are just some of the economic benefits derived from the lake. In this context the findings of the study highlights a substantial link between dependency, benefits, and education in influencing local residents’ perceptions of the lake. Further, our study could be useful to the society in terms of Ansupa lake conservation and management planning, as well as to the local government in involving locals in lake conservation initiatives and decision-making processes.
Generalized Logarithmic Species-Area Relationship resolves the Arrhenius-Gleason debate
Authors: Carey Mark , Boland John , Keppel Gunnar 
Published: April 2022

Abstract
The species-area relationship (SAR) is widely applied in ecology. Mathematically it is usually expressed as either a semi-log or power-law relationship, with the former being introduced by Gleason and the latter by Arrhenius. We here resolve the dispute about which form of the SAR to prefer by introducing a novel model that smoothly transforms between the Gleason semi-log (GSL) and Arrhenius power law (APL) forms. The model introduced has the form of lnq(S) = a + z lnA, with lnq being a generalized logarithmic function which is a linear map (y = x) for q = 0 and a logarithmic map (y = ln x) for q = 1 and q can take any intermediate value between 0 and 1. We applied this model to 100 datasets (mostly islands), linking species richness to island area. The APL was the preferred model in 68% of head-to-head comparisons with the GSL. Both models were supported in 40% of cases. In just under half (44%) of the cases an intermediate model best explained the data. The results demonstrate the utility of a simple intermediate SAR model. Visualizing the profile of the range of model fits for all q ∈ [0; 1] allows us to gain extra insight into SARs not yielded by head-to-head comparisons of GSL and APL. The mathematics related to the generalized logarithmic function introduced here promises to have application to other areas of mathematical ecology, for instance in population biology models.
Quality Characteristics of Some Algerian Olive Oils with Antioxidant Activity
Authors: SAOUDI Boudjema , LACHRAF Azzeddine , LAIB Fella , TOUARFIA Moundji , HABERRA Soumaya 
Published: April 2022

Abstract
Herein, the physicochemical properties of ten samples of olive oil from various Algerian regions (the acidity, peroxide, and saponification index, the specific extinction coefficient (K232, K270), the content of chlorophyll, carotenoids, and total polyphenols), in addition to their antioxidant activity were investigated and were compared with three other control samples. The physicochemical characteristics of the tested olive oils proved oil quality varying from virgin to extra virgin olive oil of excellent nutritious and healthy quality for the consumer according to the commercial standards recommended by the International Olive Council (IOC). Moreover, the olive oil collected samples showed that the antioxidant activity of oil samples from south Algeria (Sahara) is higher than that of Northern Algeria, and the oils of Chemlal variety exhibited higher antioxidant activity than that of Segoise variety.
TSHR Promotes Proliferation and Invasion of Papillary Thyroid Carcinoma By Regulating NF-κB Signal Pathway
Authors: Lin Xiangfeng , Ma Chi , Zheng Guibin , Sun Haiqing , Lin Xiyuan , Wei Shujian , Wu Guochang , Zheng Haitao 
Published: April 2022

Abstract
Purpose: To investigate the significance of TSHR and NF-κB P65 expression difference in thyroid papillary carcinoma, and to explore how TSHR affects the biological behavior of PTC cells by regulating NF signaling pathway .Methods: A total of 87 patients with thyroid papillary carcinoma were collected to investigate the expression of TSHR and NF-κB P65 in PTC by IHC. Tpc-1 cells overexpressing TSHR were constructed and their effects on cell biological behavior were observed by cell counting and Transwell assays. Subsequently, the expression and subcellular localization of key proteins in NF-κB signaling pathway were investigated by western blot and immunofluorescence.Results: 1. The expression of TSHR in PTC was significantly higher than normal tissues and was only negatively correlated with lymph node metastasis. The NF-κB p65 was also highly expressed in cancer tissues, and was positively associated with tumor size, membrane invasion and lymph node metastasis, and unrelated to gender and age. There was a lightly positive correlation between TSHR and NF-κB p65 expression.2. The proliferation and invasion ability of TPC-1 cells overexpressing TSHR was suppressed. the expression of P65 showed no change with TSHR in TPC-1 cells, but p-p65 and p-IκB was significantly increased with TSHR overexpressing. Finally, TSHR promoted the p65 to enter into nucleus.Conclusion: Our study uncovered TSHR may inhibited the proliferation and invasion ability of PTC by NF-κB signaling pathways. Furthermore, we revealed that TSHR may acted as a functional protein in tumor cells without the stimulation of TSH.
Effects of tetracycline on the secondary metabolitesand nutritional value of oilseed rape (Brassica napus L.)
Authors: Zhao Mengting , Li Jun , Zhou Shanshan , Rao Guiwei , Xu Dongmei 
Published: April 2022

Abstract
Secondary metabolism, which helps a plant cope with external stress, is sensitive to environmental changes and plays a prominent role in maintaining plant health. However, few studies of the effects of tetracycline on the relationships between secondary metabolism and plant stress responses have been performed. Here, secondary metabolism, nutritional value, and oxidative stress responses in oilseed rape (Brassica napus L.) exposed to tetracycline for 14 d were investigated. Tetracycline inhibited growth and biomass accumulation and decreased the chlorophyll content. The sinapine, phenol, and flavonoid contents were 118.46%, 99.67%, and 93.07% higher, respectively, but the carotenoid content was 76.47% lower in plants exposed to 8 mg/L tetracycline than the control plants. Tetracycline affected the nutritional value of oilseed rape. Tetracycline decreased the dietary fiber,soluble sugar contents, and microelement (Fe, Mn, and Zn) contents. The antioxidant system alsoresponded strongly to tetracycline. The catalase and peroxidase activities were increased and the superoxide dismutase activity was decreased by tetracycline. Tetracycline caused oxidative damage and secondary metabolite disturbances and adversely affected oilseed rape growth and quality.The results provide a new perspective on the effects of tetracycline on plants in relation to secondary metabolites and improve our understanding involved in the toxicity of tetracycline.
Efficacy of inhaled tiotropium add-on to budesonide/formoterol in patients with bronchiolitis obliterans developing after hematopoietic stem cell transplantation
Authors: Lim Jeong Uk , Park Silvia , Yoon Jae-Ho , Lee Sung-Eun , Cho Byung-Sik , Kim Yoo-Jin , Lee Seok , Kim Hee-Je , Rhee Chin Kook 
Published: April 2022

Abstract
Background: Bronchiolitis obliterans syndrome (BOS) is the lung manifestation of chronic graft-versus-host disease, and a noninfectious pulmonary sequela of hematopoietic stem cell transplantation (HSCT). Despite the combination regimen including budesonide/formoterol that was previously shown as effective, a significant proportion of patients are unresponsive. We assessed whether inhaled tiotropium add-on to the combination regimen improve pulmonary function and the chronic obstructive pulmonary disease assessment test (CAT) scores in patients with BOS.Methods: Post-HSCT patients with significant respiratory symptoms or poor pulmonary function referred to the pulmonology department of the HSCT Center of Seoul St. Mary’s Hospital, were reviewed retrospectively. Patients defined as BOS and treated with budesonide/formoterol/tiotropium combination therapy after budesonide/formoterol therapy from January 2011 to June 2019 were enrolled. Results: Total of 86 patients were evaluated. After tiotropium add-on, the absolute FEV1 increased significantly from 1.47 ± 0.49 to 1.53 ± 0.57 L (p = 0.023) and the % predicted FEV1 from 45.0 ± 12.8 to 46.8 ± 14.5% (p = 0.031). The % predicted DLCO increased significantly after tiotropium add-on (from 61.6 ± 16.7 to 64.3 ± 16.3%, p = 0.028). Among 56 patients with complete CAT scores, no significant change was present in total CAT scores. In all, 30 of the 72 patients (41.7%) evidenced FEV1 increases > 100 mL, and 20 of 56 patients (35.7%) had CAT score decreases of ≥ 2 points. When the FEV1 and CAT scores were combined, the overall response rate to tiotropium add-on was 56.2% (41/73). The response group evidenced a significantly greater FVC increase (both absolute (p < 0.001) and % predicted (p < 0.001)), and a significant decrease in the RV/TLC ratio compared to the no-response group (p = 0.006).Conclusions: Inhaled tiotropium add-on to combination budesonide/formoterol significantly improved lung function, but not respiratory symptoms, in patients with post-HSCT BOS.
Usefulness of modified distress thermometer in screening adolescents with COVID-19 for psychological distress
Authors: Gamal Yasser , Mohamed Sherif , Raheem Yasser Abdel , Elela Mohamed Abo , Badawy Ahlam 
Published: April 2022

Abstract
Background: Children and adolescents are more vulnerable than other age groups to the psychosocial effects of the COVID-19 pandemic. The modified DT (m-DT) was recently utilized for measuring the prevalence of psychological distress among adult COVID-19 patients. In the current study, we aimed to test the utilization of this m-DT in screening adolescent patients with COVID-19 for psychosocial distress.Methods: Egyptian adolescent subjects with suspected or confirmed cases of COVID-19 at a University Hospital were enrolled. Binary logistic regression tests were carried out to explore the association between the m-DT cut-off scores of 4 and the clinical variables.Results: Forty-eight percent (87/182) of the study subjects experienced significant (m-DT score ≥ 4) COVID-19 related distress. There were significant differences between those with and without significant distress with regards to length of quarantine, presence of underlying medical disorder, and presence of chronic respiratory disorders. Length of quarantine time, presence of chronic respiratory disease, worry, and fever were independent factors associated with significant distress in COVID-19 adolescent patients.Conclusions: Almost half of the enrolled Egyptian adolescents with COVID-19 experienced significant psychological distress. The m-DT was useful, as the current study had identified length of quarantine time, presence of chronic respiratory disease, worry, and fever as independent factors associated with significant distress in COVID-19 adolescents. Further studies are needed.
COVID-19 induced acute respiratory distress syndrome treated with Hyperbaric Oxygen: Interim safety report from a multicenter, randomised, open-label phase II clinical trial (COVID-19-HBO)
Authors: Kjellberg Anders , Douglas Johan , Hassler Adrian , Al-Ezerjawi Sarah , Boström Emil , Abdel-Halim Lina , Liwenborg Lovisa , Hetting Eric , Jonasdottir-Njåstad Anna-Dora , Kowalski Jan , Catrina Sergiu-Bogdan , Rodriguez-Wallberg Kenny A , Lindholm Peter 
Published: April 2022

Abstract
Purpose: A few prospective trials and case series have suggested efficacy of hyperbaric oxygen therapy (HBOT) for treatment of severe COVID-19 but safety is a concern, especially for critically ill patients. We present the safety interim analysis of the randomised controlled trial COVID-19-HBO Methods: Randomised controlled, open label, clinical trial in compliance with good clinical practice to explore the safety and efficacy of HBOT for severe COVID-19 in critically ill patients with moderate acute respiratory distress syndrome (ARDS). Between June 3 2020 and May 17 2021, 31 patients with Severe COVID-19 and moderate to severe ARDS; PaO2/FiO2 <26.7kPa (200mmHg) and at least 2 defined risk factors for ICU admission and/or mortality were enrolled in the trial and randomised 1:1 to Best practice or HBOT in addition to Best practice. Subjects allocated to HBOT received maximum 5 treatments 240 kPa, 80 minutes, during 7 days. Follow up was 30 days. Safety endpoints were analysed.Results: Adverse events (AE) were common, hypoxia was most commonly reported, there was no statistically significant difference between the groups. Numerically, serious adverse events (SAE) and barotrauma were more frequent in the control group. Numerically differences were in favor of the HBOT in PFI, NEWS but statistically not significant at day 7, and no difference was observed for the total oxygen burden and Cumulative Pulmonary oxygen Toxicity Dose (CPTD).Conclusions: HBOT appears safe as an intervention for critically ill patients with moderate to severe acute respiratory distress syndrome (ARDS) induced by COVID-19.Trial registration: NCT04327505 (March 31, 2020) and EudraCT 2020-001349-37 (April 24, 2020)