bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perioperative Acute Myocardial Infarction and Ischemia After Noncardiac Surgery: Pathophysiology, Prevention, and Nursing Implications
Authors: Harris David E. 
Published: November 2022

ABSTRACTPerioperative acute myocardial infarction (AMI) after noncardiac surgery increases the mortality rate of patients who experience it. Depending on the definition of AMI used and the patient population studied, perioperative AMI occurs in 0.01% to 10% of patients. Most instances of perioperative AMI occur within the first two days after surgery, do not present with classic myocardial infarction symptoms, and are the result of myocardial oxygen supply versus oxygen demand mismatch. Older patients; those with preexisting cardiovascular conditions; those undergoing thoracic, upper abdominal, or major vascular procedures; and those who experience perioperative hemodynamic instability are at particular risk. This article provides a clinically based review of the pathophysiology, perioperative risks, treatment options, outcomes, and nursing implications of perioperative AMI and ischemia. It provides evidence to assist perioperative nurses with meeting the physiologic and safety needs of their patients and highlights the evolving scientific understanding and clinical guidelines to promote current practice.
Quantifying Output Power and Dynamic Charge Distribution in Sliding Mode Freestanding Triboelectric Nanogenerator
Authors: Guo Xin , Shao Jiajia , Willatzen Morten , Wang Xiaolin , Wang Zhong Lin 
Published: November 2022

AbstractThe general concept of dielectric polarization density (P) is a macroscopic description of the underlying microscopic structure in the presence of an external electric field and polarized materials itself. A time‐dependent polarization PS induced by a non‐electric field also exists in practice due to the mechanically driven relative motion of media owing to the effects of contact electrification or piezoelectricity. In this work, the starting point is to consider the difference between P and PS, and how PS enters into the governing equations, since it describes the dielectric polarization density without an applied electric field, finally modifying the constitutive relations, Faraday's law, and Maxwell's equations. On this background, a 3D mathematical‐physical model for the sliding mode freestanding triboelectric nanogenerators (TENGs) is established that is taken as an example to confirm the relationship of free charge distribution and dynamics of output power. What needs to be emphasized is that the method of segmented uniform charge distribution is effective and the physical basis for modeling construction and analysis. Finally, we summarized the mathematical‐physical models of TENGs in rectangular coordinates, cylindrical coordinates, and spherical coordinates, building a bridge to reveal the underlying principle behind the microscopic polarization and energy conversion.
Quercetin alleviates subarachnoid hemorrhage‐induced early brain injury via inhibiting ferroptosis in the rat model
Authors: Jiao Dian , Xu Jianmiao , Lou Chengjian , Luo Yuhuan , Ni Chengtao , Shen Guanghong , Fang Marong , Gong Xiangyang 
Published: November 2022

AbstractEarly brain injury (EBI) refers to a series of pathophysiological brain lesions that occur within 72 hr after subarachnoid hemorrhage (SAH), which is an extremely crucial factor in the poor prognosis of patients. In EBI, ferroptosis has been proven to cause neuronal death. Quercetin (QCT) is effective in deactivating reactive oxygen species (ROS), inhibiting lipid peroxidation, and even chelating iron, but its role in SAH remains unclear. In this study, the mortality rate, severity grade of SAH, brain water content (BWC), blood–brain barrier permeability, and neurological function of the rats were detected. Moreover, mitochondrial morphology in cortical neurons were observed and their sizes were subsequently quantified. The levels of lipid peroxidation on glutathione and malondialdehyde (MDA) and glutathione peroxidase (GSH‐Px) were determined, whereas the protein expressions of glutathione peroxidase 4 (GPX4), SLC7A11 (xCT), transferrin receptor 1 (TfR1), and ferroportin‐1 (FPN1) were analyzed by western immunoblotting. The neurodegeneration involved in EBI was investigated by fluoro‐Jade C staining, while iron staining was utilized to measure iron content. Our results showed that inhibition of ferroptosis by QCT could suppress EBI and improve neurological function in SAH rats. QCT increased the expression levels of GPX4, xCT, and FPN1, while downregulated TfR1, and exerted protective effects on neurons as well as alleviated iron accumulation and lipid peroxidation in the cortex of SAH rats. In conclusion, our study revealed that QCT might alleviate the EBI by inhibiting ferroptosis in SAH rats.
A practice‐based study of cultural humility and well‐being among psychotherapy clients
Authors: Choe Elise J. Y. , Jankowski Peter J. , Sandage Steven J. , Crabtree Sarah A. , Captari Laura E. 
Published: November 2022

AbstractOne trend in psychotherapy research involves examining client factors to better understand change. Some have framed client factors as virtues. Humility is one virtue that has gained attention with evidence that suggests humility may help facilitate therapeutic change. A specific type of humility, cultural humility, however, has not been closely examined as a client factor. Cultural humility is a relational virtue that addresses an individual's ability to be open towards cultural differences and can be helpful in buffering diverse relational dynamics (e.g., student and teacher, family members and friends with different beliefs). In this study, we examined client change in cultural humility and well‐being using group‐based trajectory modelling. We also examined differentiation as a predictor of trajectory membership and compared trajectories on levels of symptoms. Results suggested that a subgroup of clients showed significant increases in cultural humility and well‐being. Further analyses found that clients with higher levels of initial differentiation were more likely to belong to the growth trajectory. This same trajectory also decreased in symptoms over time.
The Ethanol Extract of Syringa oblata Heartwood, a Mongolian Folk Medicine Containing Major Lignans, Exerts Analgesic and Sedative Effects on Mice
Authors: Xu Jixuan , Tai Badalahu , Jiao Shungang , Wuken Shana , Chen Hongying , Chen Panlong , Zhang Zefeng , Gao Xiaoli , Chai Xingyun 
Published: November 2022

AbstractThe heartwood of Syringa oblata Lindl. (SO) is one of Mongolian folk medicines to treat insomnia and pain, while its pharmacological evaluation and underlying mechanism remain unclear. In this study, the sedative effect of ethanol extract of SO (ESO) was evaluated with the locomotor activity test and the threshold dose of pentobarbital sodium‐induced sleep test in mice, and the hot plate test, acetic acid‐induced writhing test, and formalin test in mice were used to evaluate its analgesic effect. The underlying mechanism of ESO analgesia was explored by RT‐PCR and western blot analysis, which is associated with the regulation of the NF‐κB signaling pathway. Besides, the main constituents of ESO were characterized by LC/MS data analysis and comparison with isolated pure compounds. The current findings brought evidence for clinical application and further pharmacological and phytochemical studies on SO.
Isolated schwannoma originating from the infraorbital nerve: A case report
Authors: Shafie Mahan , Mayeli Mahsa , Rajabi Mohammad Taher 
Published: November 2022

AbstractAs a benign isolated and encapsulated tumor originating from the nerve sheaths, schwannomas rarely appear on the cranial nerves, among which infraorbital nerve schwannomas are highly uncommon. We report a case of isolated infraorbital nerve schwannoma in a 58‐year‐old male patient with a clinical manifestation of proptosis in the affected eye.
Functional denture obturator for marsupialization of residual cyst: A novel approach
Authors: Etemadi Sh Milad , Aghamohseni MohammadMostafa , Norouzi Atefeh , Sadeghi Sarina , Ranjbarian Parisa 
Published: November 2022

AbstractIn this report, we have introduced a novel technique for marsupialization treatment in a 50‐year‐old edentulous female patient with residual cysts in the mandibular bone. The clinical symptoms and para‐clinical founding in addition to the surgical procedure and post‐operative outcome have been discussed.
Successful endovascular repair of complicated pseudoaneurysm using Perclose ProGlide: A novel concept
Authors: Kodama Takahide , Yamaguchi Tetsuo , Fujiwara Hideomi , Kuwabara Masanari 
Published: November 2022

AbstractIatrogenic pseudoaneurysm is common vascular complications of angiographic procedures. Patients with uncomplicated pseudoaneurysms can be managed with ultrasound‐guided techniques. However, for complicated pseudoaneurysms, surgical repair of the artery is mandatory. We report a case of successful repair of complicated pseudoaneurysm using an access‐site closure device, Perclose ProGlide™ without a surgical approach.
Compensation Effect in Catalytic Oxidation of Carbon Monoxide
Authors: Balla Ancuţa , Marcu Cristina , Szücs-Balázs József-Zsolt 
Published: November 2022

AbstractThe compensation effect in heterogeneous catalytic reactions is related to an appropriate change in the activation energy. A compensation effect is expected if a linear relationship between activation energy and pre‐exponential factor, or activation enthalpy and entropy, takes place for a reaction in the presence of different catalysts. This study aims to identify the occurrence of the compensation effect in CO oxidation reaction to CO2 catalyzed by CuO/Al2O3, Ni/TiO2, Ni/Al2O3, and Pd/Al2O3.
A year of experience with COVID‐19 in patients with cancer: A nationwide study
Authors: Khosravifar Mina , Koolaji Sogol , Rezaei Negar , Ghanbari Ali , Hashemi Seyedeh Melika , Ghasemi Erfan , Bitaraf Ali , Tabatabaei‐Malazy Ozra , Rezaei Nazila , Fateh Sahar Mohammadi , Dilmaghani‐Marand Arezou , Haghshenas Rosa , Kazemi Ameneh , Pakatchian Erfan , Kompani Farzad , Djalalinia Shirin 
Published: November 2022

AbstractBackgroundCancer is a major public health problem and comorbidity associated with COVID‐19 infection. According to previous studies, a higher mortality rate of COVID‐19 in cancer patients has been reported.AimsThis study was undertaken to determine associated risk factors and epidemiological characteristics of hospitalized COVID‐19 patients with cancer using a nationwide COVID‐19 hospital data registry in Iran for the first time.MethodsIn this retrospective study, we used a national data registry of hospitalized patients with Severe Acute Respiratory Syndrome (SARS) symptoms and patients with confirmed positive COVID‐19 PCR between 18 February 2020 and 18 November 2020. The patients were classified into two groups patients with/without malignancy. Logistic regression model was utilized to analyze demographic factors, clinical features, comorbidities, and their associations with the disease outcomes.ResultsIn this study, 11 068 and 645 186 in‐patients with SARS symptoms with and without malignancy were included, respectively. About 1.11% of our RT‐PCR‐positive patients had cancer. In patients with malignancy and COVID‐19, older ages than 60 (OR: 1.88, 95% CI: 1.29–2.74, p‐value: .001), male gender (OR: 1.43, 95% CI: 1.16–1.77, p‐value: .001), concomitant chronic pulmonary diseases (CPD) (OR: 1.75, 95% CI: 1.14–2.68, p‐value: .009), and presence of dyspnea (OR; 2.00, 95% CI: 1.60–2.48, p‐value: <.001) were associated with increased mortality rate.ConclusionGiven the immunocompromised state of patients with malignancy and their vulnerability to Covid‐19 complications, collecting data on the comorbidities and their effects on the disease outcome can build on a better clinical view and help clinicians make decisions to manage these cases better; for example, determining special clinical care, especially in the shortage of health services.
Sustainability and firm value in the oil and gas industry—A vicious circle?
Authors: Kaupke Katharina , zu Knyphausen‐Aufseß Dodo 
Published: November 2022

AbstractThe relationship between sustainability (or CSR) and company value has been intensively researched in recent times. However, the specifics of individual industries have not been sufficiently taken into account. Our study aims to fill this research gap. We focus on the oil and gas industry as a particularly powerful and controversial industry. Based on legitimacy theory and institutional theory, we argue that the relationship between firm value and sustainability is negative in this industry. Our sample consists of 205 firms with 1515 observations. Using a simultaneous equation system (3SLS) to determine its direction, we find the two to be negatively interrelated in a vicious circle. Furthermore, we find evidence for a moderating role of the renewable energy share of a company's headquarter country as well as the company's industry segment. The explanatory power continues to hold with consideration of a profitability measure (Return on Sales) instead of firm value.
Neuroendocrine tumor of the ampulla of Vater treated with endoscopic papillectomy: A case report
Authors: Hamada Koichi , Irisawa Atsushi , Horikawa Yoshinori , Shiwa Yoshiki , Techigawara Kae , Ishikawa Masafumi , Nagahashi Takayuki , Fukushima Daizo , Nishino Noriyuki , Sakuma Hideo , Honda Michitaka 
Published: November 2022

AbstractWe report the case of a 62‐year‐old female with a 6.3‐mm low‐grade neuroendocrine tumor of the ampulla of Vater, who underwent an endoscopic papillectomy. An endoscopic papillectomy was performed without complications. In the 26 months of follow‐up, no local recurrence or metastasis occurred. Endoscopic treatment of ampullary neuroendocrine tumors is controversial. However, endoscopic papillectomy may be considered a treatment option if neuroendocrine tumors are small (<10 mm), have a low grade (G1), or do not have muscle layer or bile duct invasion.
Analysis of highly potent synthetic opioid nitazene analogs and their positional isomers
Authors: Kanamori Tatsuyuki , Okada Yuki , Segawa Hiroki , Yamamuro Tadashi , Kuwayama Kenji , Tsujikawa Kenji , Iwata Yuko T. 
Published: November 2022

AbstractFour nitazenes (metonitazene, etonitazene, protonitazene, and isotonitazene), highly potent benzimidazole synthetic opioids, and their four nitro group positional isomers (isonitazenes) were synthesized and analyzed using infrared (IR) spectroscopy, gas chromatography/mass spectrometry (GC/MS), and liquid chromatography/mass spectrometry (LC/MS). In addition, the agonistic activity of all compounds at the human μ‐opioid receptor was measured using a cell‐based assay system. In the IR spectra, characteristic peaks for nitazenes and isonitazenes were observed. In GC/MS, all compounds were well separated on the chromatogram, although distinguishing nitazenes from the corresponding isonitazenes by electron ionization mass spectra was difficult. In LC/MS, all compounds were detected in both positive and negative modes of electrospray ionization. Characteristic fragment ions were observed in the product ion spectra of isonitazenes, enabling nitazenes to be distinguished from isonitazenes. All nitazenes tested demonstrated higher agonistic activity at the human μ‐opioid receptors than the synthetic opioid fentanyl. The agonistic activities of isonitazenes were 11–35 times lower than those of the corresponding nitazenes. However, iso‐etonitazene and iso‐isotonitazene showed moderate activity similar to that of fentanyl, indicating that these drugs could cause poisoning at a comparable level as fentanyl, if these drugs are abused in the future.
Reduction in biomass of freshwater arctic vegetation by foraging and nesting hyperabundant herbivores shows recovery
Authors: Kellett Dana K. , Alisauskas Ray T. 
Published: November 2022

AbstractArctic‐nesting geese are specialist herbivores of grasses and sedges (collectively, graminoids). Under moderate grazing pressure, these migratory herbivores can create and maintain arctic grazing lawns with high nutritional content and low aboveground biomass. Nutrient and energy subsidies from southern agricultural landscapes during winter have improved survival among populations of Ross's (Anser rossii) and lesser snow geese (Anser caerulescens caerulescens), leading to marked population growth. Resulting goose hyperabundance has raised conservation concern for resilience of arctic ecosystems to withstand cumulative and intense pressures of herbivory and nest construction. We used both design‐based (experimental herbivore exclosures) and model‐based methods to investigate changes to plant community structure in direct response to foraging and nesting by these species within the Queen Maud Gulf (Ahiak) Migratory Bird Sanctuary, Nunavut, Canada. Annual nest construction and foraging by up to ~1.3 million geese at a large colony at Karrak Lake markedly reduced aboveground biomass of forage (graminoids) and non‐forage (foliose and fruticose lichens) vegetation, with spatial variation in reduction associated with intensity of use by geese. Within vast brood‐rearing regions, foraging reduced above‐ and belowground plant biomass of lowland plant communities by 61% and 29%, respectively, between 1994 (when herbivore exclosures were established) and 2017. In addition to landscape diversity associated with abiotic properties created by geomorphic processes, long‐term herbivory by geese further increased spatial heterogeneity in vegetation at the landscape scale. Although foraging geese nearly completely depleted aboveground plant biomass in some parts of their brood‐rearing areas, belowground biomass was largely conserved, and thus, plant communities had strong potential for aboveground regeneration. We propose that the effects of high‐density nesting and foraging by Ross's and lesser snow geese in the central Canadian Arctic, while extensive, are ephemeral and prone to reversion following cessation of grazing and nesting pressure, such as that afforded by shifts in herbivore distribution or local population decline.
One‐Pot Synthesis of Functionalized Isoindolinones and Their Bis(isoindolinone)ethane Derivatives
Authors: Purohit Deepak , Singh Rawat Kundan , Parveen Sajiya , Prakash Vats Ravi , Prakash Sharma Chandra , Goel Atul 
Published: November 2022

AbstractHighly efficient one‐pot synthesis of a series of substituted 3‐methylene‐isoindolinones (3 a–x), bis(isoindolinone)ethanes (4 a–d) and 3‐hydroxy‐isoindolinones (6 a–h) derivatives is portrayed from easily accessible starting materials such as 2‐cyanobenzaldehydes (1 a–h) and different aryl/heteroaryl methyl ketones (2 a–k). The structure of Z‐isomer of 3‐methylene‐isoindolinone 3 x was confirmed by single crystal X‐ray analysis. The reaction mechanism studies by control experiments and using O18‐labelled water revealed that the reaction was initiated by attack of a conjugate base of aryl/heteroaryl methyl ketones (2 a–k) to aldehyde group of 1 a–h followed by intramolecular oxidative cyclization involving nitrile functionality to furnish isoindolinone derivatives in good to excellent yields.
How to make your diversity, bias training a positive experience
Authors: Sutton Halley 
Published: November 2022

LAS VEGAS — “This is a training about how to make diversity training and bias training palatable to law enforcement,” Lewis Eakins, Ph.D., CPP, Vice President for Public Safety and Emergency Management at Ivy Tech Community College in Indiana, said. Eakins spoke at the recent annual conference for the International Association of Campus Law Enforcement Administrators.
The relevance of rich club regions for functional outcome post‐stroke is enhanced in women
Authors: Bonkhoff Anna K. , Schirmer Markus D. , Bretzner Martin , Hong Sungmin , Regenhardt Robert W. , Donahue Kathleen L. , Nardin Marco J. , Dalca Adrian V. , Giese Anne‐Katrin , Etherton Mark R. , Hancock Brandon L. , Mocking Steven J. T. , McIntosh Elissa C. , Attia John , Cole John W. , Donatti Amanda , Griessenauer Christoph J. , Heitsch Laura , Holmegaard Lukas , Jood Katarina , Jimenez‐Conde Jordi , Kittner Steven J. , Lemmens Robin , Levi Christopher R. , McDonough Caitrin W. , Meschia James F. , Phuah Chia‐Ling , Ropele Stefan , Rosand Jonathan , Roquer Jaume , Rundek Tatjana , Sacco Ralph L. , Schmidt Reinhold , Sharma Pankaj , Slowik Agnieszka , Sousa Alessandro , Stanne Tara M. , Strbian Daniel , Tatlisumak Turgut , Thijs Vincent , Vagal Achala , Wasselius Johan , Woo Daniel , Zand Ramin , McArdle Patrick F. , Worrall Bradford B. , Jern Christina , Lindgren Arne G. , Maguire Jane , Wu Ona , Rost Natalia S. ,   the MRI‐GENIE and GISCOME Investigators and the International Stroke Genetics Consortium
Published: November 2022

AbstractThis study aimed to investigate the influence of stroke lesions in predefined highly interconnected (rich‐club) brain regions on functional outcome post‐stroke, determine their spatial specificity and explore the effects of biological sex on their relevance. We analyzed MRI data recorded at index stroke and ~3‐months modified Rankin Scale (mRS) data from patients with acute ischemic stroke enrolled in the multisite MRI‐GENIE study. Spatially normalized structural stroke lesions were parcellated into 108 atlas‐defined bilateral (sub)cortical brain regions. Unfavorable outcome (mRS > 2) was modeled in a Bayesian logistic regression framework. Effects of individual brain regions were captured as two compound effects for (i) six bilateral rich club and (ii) all further non‐rich club regions. In spatial specificity analyses, we randomized the split into “rich club” and “non‐rich club” regions and compared the effect of the actual rich club regions to the distribution of effects from 1000 combinations of six random regions. In sex‐specific analyses, we introduced an additional hierarchical level in our model structure to compare male and female‐specific rich club effects. A total of 822 patients (age: 64.7[15.0], 39% women) were analyzed. Rich club regions had substantial relevance in explaining unfavorable functional outcome (mean of posterior distribution: 0.08, area under the curve: 0.8). In particular, the rich club‐combination had a higher relevance than 98.4% of random constellations. Rich club regions were substantially more important in explaining long‐term outcome in women than in men. All in all, lesions in rich club regions were associated with increased odds of unfavorable outcome. These effects were spatially specific and more pronounced in women.
The Chiral Induced Spin Selectivity Effect What It Is, What It Is Not, And Why It Matters
Authors: Fransson J. 
Published: November 2022

AbstractThe chiral induced spin selectivity effect is an excited states phenomenon, which can be probed using photo‐spectroscopy as well as transport measurements. On the one hand such measurements represent averaged quantities, on the other hand nearly all theoretical descriptions, with only a few exceptions, have been concerned with energy dependent properties of the pertinent structures. While those properties may or may not be relevant for the chiral induced spin selectivity effect, many of those properties have been attributed as being the, or part of the, origins of the effect. Here, it is demonstrated that, for instance, the spin‐resolved transmission provides little, if any, information about the chiral induced spin selectivity effect. Moreover, although effective single‐electron theory can be used in this context, reasons are given for why such descriptions are not viable.