bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of olfactory bulb volume and olfactory sulcus depth in patients with panic disorder and depressive disorder: An MRI study
Authors: Cengiz Gül Ferda , Serin Halil İbrahim , Cengiz Ceyhun 
Published: March 2022

Abstract

Background:
Although some studies have shown decreases in the olfactory bulb (OB) volume and olfactory function in depressive disorder, there are no studies investigating OB volume in patients with panic disorder.

Aim:
The aim of this study was to investigate whether there was a change in OB volume and olfactory sulcus (OS) depth in patients with panic and depressive disorder when compared with the control group, and which group was more affected by comparing the two disease groups.

Methods:
Data of 51 patients with panic disorder and 56 patients with depressive disorder were obtained by scanning the database of the hospital retrospectively. The control group consisted of 56 subjects without panic and depressive disorder. OB volume and OS depth measurements were performed on cranial magnetic resonance imaging (MRI).

Results:
Bilateral OB volume of the panic and depressive disorder groups were significantly lower than those of the control group. The lowest volume was found in depressive patients. There was no significant difference between the groups with respect to OS measurements. When OB volume and OS depth differences between the genders were evaluated, a statistically significant difference was not determined.

Conclusion:
Reduced OB volume was determined in both panic and depressive disorder patients, and clarification of these preliminary findings may contribute to the pathophysiology of panic and depressive disorders.
A quantitative study on completeness rate of documentation in psychiatric medical records
Authors: Ebnehoseini Zahra , Khorasani Hediye , Moharari Fatemeh , Ebrahimi Ali Reza , Boroujerdi Masoumeh , Jamei Fatemeh , Mehri Mohammad Reza , Tabesh Hamed 
Published: March 2022

Abstract

Background:
Mental disorders are one of the leading causes of illness and disability worldwide. According to the World Health Organization (WHO), one in four people in the world will be affected by mental or neurological disorders during their lifetime. Regular evaluation of mental health outcomes plays an important role in making decisions about timely treatment of the patient. Studies show that a medical record does not provide enough information about the diagnosis, current symptoms, psychiatric medications, and side effects of current medications and treatments for ongoing health care. In this study, the completeness of paper-based psychiatric records was investigated.

Aim:
The current study aimed to explore the completeness rate of paper-based psychiatric medical records (PMRs) and to investigate the factors effective on documentation status.

Setting:
The study was conducted in Ebnesina and Dr. Hejazi Psychiatric Hospital and Education Center. The case hospital is a psychiatric teaching hospital, which has 900 beds.

Materials and Methods:
The completeness rate of PMRs was determined using descriptive statistics. Fleiss’ Kappa agreement and effective factors on PMRs’ documentation status were assessed.

Results:
In total, 83.65% (n = 312) of the PMRs had at least one documentation defect. A significantly higher level of documentation completeness rate between different psychiatric wards was observed.

Conclusion:
Based on our results, it is suggested to conduct regular evaluation and provide feedback to the health-care providers, and conduct training courses.
Six-month buprenorphine-naloxone treatment is associated with neurocognitive function improvement in opioid dependence
Authors: Ghosh Abhishek , Mahintamani Tathagata , Rana Devender K. , Basu Debasish , Mattoo Surendra K. 
Published: March 2022

Abstract

Background and Aim:
The number of longitudinal studies on cognitive functions in patients on buprenorphine-based agonist treatment is limited. Our objective was to assess the change in neurocognitive functions over the first 6 months of buprenorphine-naloxone (BNX) treatment for opioid dependence (OD) and compare cognitive functions on BNX and controls.

Methods:
We selected 60 patients with OD aged 18 to 55 years and 20 sex-matched controls; and excluded patients with other substance dependence, human immunodeficiency virus (HIV), head injury, epilepsy, and severe mental illness. We assessed patients thrice: at baseline, 3, and 6 months and Controls once. Cognitive tests included Wisconsin card sorting test (WCST), Iowa gambling task (IGT), trail making tests A and B (TMT-A and B), verbal and visual N-back test (NBT), and standard progressive matrices (SPM). We measured with-in group effect size with Cohen’s D (d).

Results:
A total of 24 participants completed at least one follow-up; 17 completed both follow-up assessments. All participants were men. At baseline, the patients performed worse than healthy controls in IGT, TMT-A, and B, and visual and verbal NBT. At 3 months, the performance of visual NBT improved significantly (d = 1.2 for NBT1; 1.3 for NBT2). At 6 months, additional performance improvements were seen in WCST (“perseverative error” d = 1.2), IGT (“net total score” d = 1.2), TMT-A (d = 1.1), and verbal NBT (“omission error” d = 1.7). Except for visual-NBT, results did not differ between patients and controls at both follow-ups.

Conclusion:
Cognitive flexibility, decision making, attention, working memory, and psychomotor speed showed improvements over 6 months of a stable dose of BNX.
Impact of cancer diagnosis on use of smokeless tobacco: A descriptive study of patient-relative dyads
Authors: Shukla Avinash , Tikka Sai Krishna , Singh Lokesh K. , Arora Ripudaman , Singh Sharda , Mahant Supriya , Das Jyoti Ranjan , Verma Sachin 
Published: March 2022

Abstract

Background:
The time of cancer diagnosis is considered as a teaching moment with regard to tobacco cessation.

Aim:
In view of the limited studies focussing on smokeless tobacco (SLT), we aimed to assess the patterns of SLT use, attitudes toward SLT use in the context of cancer diagnosis, and factors associated with quitting SLT in dyads consisting newly diagnosed patients with head and neck cancers and their relatives.

Material and Method:
A total of 106 such dyads were assessed on cross-sectional study design. The patients included in the study were above 18 years of age of either sex with a recent (i.e., <6 months) diagnosis of head and neck (lip, tongue, mouth, oropharynx, hypopharynx, pharynx, and larynx) cancer (HNC), not having undergone any surgical intervention for the same and having used SLT for at least 6 months continuously prior to diagnosis of HNC. For each patient, one family member who was aged 18 years or above and lived for at least past 1 year with the patient was included.

Result:
We found that 60.4% of patients and 6.53% of relatives quit SLT use after the diagnosis of cancer. However, motivation to quit was greater despite continued SLT use, in both patients and relatives. Reasonable number of patients and relatives reported awareness regarding health warnings and long-term consequences of SLT use on cancer. For patients, use of only one form of SLT, presence of 2 or more males in the family using SLT, and presence of another tobacco-related medical disorder in the family were significantly higher in those who quit.

Conclusion:
The diagnosis of cancer might indeed act as a “teaching moment” for many users but this effect is not extendable on to their relatives.
Prevalence and its correlates of anxiety disorders from India’s National Mental Health Survey 2016
Authors: Manjunatha Narayana , Jayasankar Pavithra , Suhas Satish , Rao Girish N. , Gopalkrishna Gururaj , Varghese Mathew , Benegal Vivek ,   NMHS National Collaborators Group
Published: March 2022

Abstract

Introduction:
Anxiety disorders (ADs) impact the quality of life and productivity at an individual level and result in substantial loss of national income. Representative epidemiological studies estimating the burden of ADs are limited in India. National Mental Health Survey (NMHS) 2016 of India aimed to strengthen mental health services across India assessed the prevalence and pattern of public health priority mental disorders for mental health-care policy and implementation. This article focuses on the current prevalence, sociodemographic correlates, disability, and treatment gap in ADs in the adult population of NMHS 2016.

Materials and Methods:
NMHS 2016 was a nationally representative, multicentered study across 12 Indian states during 2014–2016. Diagnosis of ADs (generalized AD, panic disorder, agoraphobia, and social AD) was based on Mini-International Neuropsychiatric Interview 6.0.0. Disability was by Sheehan’s Disability Scale.

Results:
The current weighted prevalence of ADs was 2.57% (95% confidence interval: 2.54–2.60). Risk factors identified were female gender, 40–59 age group, and urban metro dwellers. Around 60% suffered from the disability of varying severity. The overall treatment gap for ADs was 82.9%.

Conclusions:
The burden of AD is similar to Depressive disorders, and this article calls for the immediate attention of policymakers to institute effective management plans in existing public health programs.
Mortality in Dermatology
Authors: Bhandare Prachi , Navya Annam , Ghodge Rakhi , Shukla Pankaj , Gupta Taruna 
Published: March 2022

Introduction:
Contrary to the general perception that the field of dermatology rarely encounters managing critical patients and dealing with mortality, severe and extensive dermatological conditions can be lethal in the absence of timely intervention.

Aims and Objectives:
The aim was to study in detail regarding the deaths and the various factors associated with it in patients admitted with dermatological conditions in a tertiary care center over a period of 10 years.

Materials and Methods:
It was a retrospective, record-based, observational study over a period of 10 years (2011–2021) in a tertiary care hospital consisting of 49 cases. After obtaining institutional ethical clearance, the information was obtained from medical records section. The relevant details of patients were entered in a specially formulated proforma.

Results:
A total of 3491 patients were admitted to the Department of Dermatology, Goa Medical College, during the study period of 10 years from January 2011 to August 2021. Among these, 49 patients succumbed to their skin condition, with an overall mortality percentage of 1.4%. Drug reactions were the most commonly encountered diagnosis in 17 patients (34.69%) which was closely followed by vesiculobullous disorders with 14 (28.57%) cases and infections in 10 (20.40%) cases.

Conclusion:
Drug reactions, vesiculobullous disease, and infections were the main causes of mortality in our series of patients. Extensive skin and mucosal involvement, multisystem involvement, declining age, delay in treatment received, and onset of sepsis were some of the major factors contributing to mortality. In our study, a high proportion of 46.93% of the patients were above the age of 60 years, out of which 56.52% had vesiculobullous disease. Hence, a special focus on geriatric dermatology deserves attention, especially in tertiary care centers.
Mucormycosis in the Setting of the Covid-19 Pandemic in Patients Without Exposure to Steroids and Oxygen
Authors: Gautam Sachin , Daga Mradul Kumar , Mawari Govind , Kumar Naresh , Rohatgi Ishan , Hussain Maryam , Ramteke Vaishali Vinod , Garg Sandeep , Kumar Suresh , Singh Sarika , Singh Ishwar 
Published: March 2022

Background:
Sudden surge of mucormycosis cases in India needs an urgent attention as multiple factors have been implicated. However, diabetes mellitus remains to be one of the most important and modifiable factors.

Methodology:
We prospectively followed 11 patients with mucormycosis in May 2021 and June 2021, admitted to our hospital to study the possible etiologies.

Results:
Out of the 11 patients, six were males and five were females, with an average age of 52.45 years. Type 2 diabetes mellitus was the ubiquitous comorbidity, and every patient presented with uncontrolled hyperglycemia (six out of them were in diabetic ketoacidosis). Glycated hemoglobin levels ranged from 10.2% to 15.1%. Out of 11 patients, four patients were non-COVID, whereas five patients had a history of COVID-19 infection. All these five post COVID-19 patients presented approximately 20 days after recovery, out of which one patient had severe infection who was hospitalized. The remaining two patients were COVID-19-positive. Out of 11 patients, 10 patients had rhino-orbital mucormycosis at presentation, among which four patients had cerebral involvement, and one out of them later developed invasive disease. However, one patient had only pulmonary mucormycosis at presentation. Serum ferritin was raised in all the patients, and six had serum zinc levels below the reference range. Serum flow cytometry showed leukopenia with normal CD4:CD8 ratio in seven patients. In the clinical outcome, six patients expired, whereas five patients responded to the treatment and were discharged on oral posaconazole therapy.

Conclusion:
From our study, it is quite evident that uncontrolled diabetes and its complications such as diabetic ketoacidosis were an important risk factor for the occurrence of mucormycosis in COVID-19 patients as well as non-COVID-19 patients, even without exposure to steroids or oxygen. Thus, blood glucose levels should be kept at optimum level during the management of COVID-19 patients.
Clinical Course of Children with Campylobacter Gastroenteritis With and Without Co-Infection in Lima, Peru
Authors: Munoz Galo Amaro , Riveros-Ramirez Maribel Denise , Chea-Woo Elsa , Ochoa Theresa J. 
Published: March 2022

ABSTRACT.
This study describes the clinical course of gastroenteritis caused by Campylobacter spp. as a single-infection versus coinfection and the corresponding changes that occur according to the treatment received, in children between 12 and 24 months of age. This descriptive study is based on the data of a pediatric cohort conducted between 2008 and 2011 of 555 children in Lima, Peru. Ninety-six diarrheal episodes with positive cultures for Campylobacter spp. were evaluated. In 52 episodes, empirical antibiotic treatment was started before pathogen isolation. Of these 96 episodes, 64.6% were coinfections with other pathogens. Coinfections were led by Escherichia coli, norovirus, and Giardia. Compared with single-infection episodes, coinfections had a mean symptom duration of 6.6 versus 5.7 days, a mean frequency of bowel movements per episode of 18.9 versus 14.8, and occurrence of vomiting and fever in 24.2% versus 14.7% of patients. Most of the patients with more severe clinical features at diagnosis were prescribed macrolides as empiric treatment. In the single-infection group, symptom duration was 7.2 ± 3.3 days in the macrolide-treated group and 7.9 ± 2.7 days in the nonmacrolide group. Diarrhea caused by coinfection appeared to be generally more severe than a single-pathogen. Patients with more severe clinical courses who received macrolides treatment might have had a faster recovery than patients who received nonmacrolides.
Radial anisotropy and S-wave velocity depict the internal to external zone transition within the Variscan orogen (NW Iberia)
Authors: Acevedo Jorge , Fernández-Viejo Gabriela , Llana-Fúnez Sergio , López-Fernández Carlos , Olona Javier , Pérez-Millán Diego 
Published: March 2022

Abstract. The cross-correlation of ambient noise records registered by seismic networks has proven to be a valuable tool to obtain new insights into the
crustal structure at different scales. Based on 2 to 14 s period Rayleigh and Love dispersion data extracted from the seismic ambient noise
recorded by 20 three-component broadband stations belonging to two different temporary experiments, we present the first (i) upper-crustal
(1–12 km) high-resolution shear wave velocity and (ii) radial anisotropy variation models of the continental crust in NW Iberia. The area
of study represents one of the best-exposed cross sections along the Variscan orogen of western Europe, showing the transition between the external
eastern zones towards the internal areas in the west. Both the 2-D maps and an E–W transect reveal a close correspondence with the main geological
domains of the Variscan orogen. The foreland fold-and-thrust belt of the orogen, the Cantabrian Zone, is revealed by a zone of relatively low shear
wave velocities (2.3–3.0 km s−1), while the internal zones generally display higher homogeneous velocities
(> 3.1 km s−1). The boundary between the two zones is clearly delineated in the models, depicting the arcuate shape of the orogenic
belt. The velocity patterns also reveal variations of the elastic properties of the upper crust that can be linked to major Variscan structures,
such as the basal detachment of the Cantabrian Zone, the stack of nappes involving pre-Variscan basement, or sedimentary features such as the
presence of thick syn-orogenic siliciclastic wedges. Overall, the radial anisotropy magnitude varies between −5 % and 15 % and increases
with depth. The depth pattern suggests that the alignment of cracks is the main source of anisotropy at < 8 km depths, although the
intrinsic anisotropy seems to be significant in the West Asturian–Leonese Zone, the low-grade slate belt adjacent to the Cantabrian Zone. At
depths > 8 km, widespread high and positive radial anisotropies are observed, which we attribute to the presence of subhorizontal
alignments of grains and minerals in relation to the pre- or syn-orogenic deformation associated with the Variscan orogenesis.
Hubungan Antara Variabel Ekonomi Makro dengan Pembiayaan UKM (Usaha Kecil Menengah) Perbankan Syariah di Indonesia
Authors: Hermawan Irwan , Herdina Vina 
Published: March 2022

Tujuan dari makalah ini adalah menguji Hubungan antara Variabel Makroekonomi dengan Pembiayaan Sektor Usaha Kecil dan Menengah (UKM) pada Perbankan Syariah di Indonesia, antara lain Pengaruh variabel BI Rate terhadap Pertumbuhan Pembiayaan sektor UKM Perbankan Syariah, Pengaruh variabel Nilai Tukar terhadap Pertumbuhan Pembiayaan Sektor UKM Perbankan Syariah, Pengaruh variabel PDB terhadap Pertumbuhan Pembiayaan UKM Perbankan Syariah. Penelitian ini menggunakan pendekatan kuantitatif. Data yang digunakan dalam penelitian ini adalah data sekunder yang merupakan Data Time Series. Data dikumpulkan dari Laporan Triwulanan OJK (Otoritas Layanan Keuangan). Hubungan antara variabel makro dan pertumbuhan Pembiayaan UKM Perbankan Syariah, menjadikan variabel makro sebagai salah satu indikator yang dapat digunakan untuk menentukan pergerakan pertumbuhan Pembiayaan Perbankan Syariah, variable-variabel Makro meliputi BI Rate, Nilai Tukar, dan PDB. Penelitian ini diharapkan bermanfaat bagi pengembangan Ekonomi dan Keuangan Islam di Indonesia, khususnya di sektor perbankan Islam, dengan memberikan informasi tambahan kepada publik tentang keunggulan sistem ekonomi Islam. Penelitian ini memiliki implikasi penting bagi Sektor Perbankan Syariah dengan menginformasikan pengaruh Variabel Makroekonomi pada Pertumbuhan Pembiayaan UKM Perbankan Syariah.
POTENSI KEBERAGAMAN ETNIK DALAM MEWUJUDKAN HARMONISASI SOSIAL DI KOTA KUPANG
Authors: Wula Zainur 
Published: March 2022

Perbedaan etnik dan latar belakang sosial budaya merupakan suatu kenyataan kehidupan sosial dan merupakan anugerah Tuhan yang terbesar bagi kehidupan umat manusia. Potensi keragaman etnik yang besar dapat memberi dampak positif dalam meningkatkan persatuan serta mewujudkan pembangunan kesejahteraan hidup umat manusia. Dalam kenyataan potensi etnik selalu djadikan kepentingan politik tertentu yang melahirkan konflik dalam masyarakat. Penelitian ini bertujuan untuk mengkaji potensi etnik yang berbeda-beda dapat mewujudkan harmonisasi sosial Kota Kupang. Teknik analisis secara deskriptif, menafsirkan dan menguraikan hasil wawancara, observasi dan diskusi group, referensi dan teori terkait. Hasil penelitian menunjukkan bahwa potensi keberagaman etnik merupakan modal dasar dalam mewujudkan harmonisasi sosial di Kota Kupang. Potensi etnik juga bisa berdampak negatif jika tidak dikelola secara baik menimulkan konflik sosial budaya. Kota Kupang pernah mengalami konflik keagamaan dan etnik. Pengelolaan keragaman etnik yang sangat baik dengan mengakomodir seluruh potensi dari berbagai wilayah Nusa Tenggara Timur yang ada di Kota Kupang dan nilai-nilai kearifan lokal dapat mewujudkan harmonisasi sosial. Modal sosial yang dimiliki masyarakat adalah ikatan Paguyuban, kelompok arisan berdasarkan etnik, wilayah, kepulauan, Kecamatan dan marga.
PENGETAHUAN TENTANG COVID-19 DAN PEMERIKSAAN KEHAMILAN DI MASA NEW NORMAL
Authors: Pratama Renda Natalina 
Published: March 2022

Latar Belakang: Kondisi ibu hamil merupakan hal yang fisiologis. Namun risiko/factor yang mempengaruhi terjadinya kegawatdaruratan harus tetap diantisipasi. Pemeriksaan kesehatan ibu hamil di masa new normal tetap dapat dilakukan dengan menjaga protocol kesehatan kecuali ada tanda bahaya. Tujuan: Untuk mengetahui bagaimana hubungan pengetahuan ibu tentang Covid-19 dengan frekuensi pemeriksaan kehamilan selama pandemic Covid-19. Metode: Penelitian ini dilakukan di PMB Husniyati Palembang dengan responden sebanyak 40 ibu hamil. Jenis penelitian ini penelitian analitik yang menganalisis hubungan variabel independent dengan variabel dependen menggunakan Uji Chi Square. Pengambilan sampel dilakukan secara accidental sampling selama waktu penelitian. Hasil: analisis statistik diperoleh hasil tidak terdapat hubungan antara pengetahuan ibu tentang Covid-19 dengan frekuensi pemeriksaan ANC dengan nilai p-value sebesar 0,309 atau Sig.> 0,05. Kesimpulan: Hasil penelitian ini diharapkan dapat meningkatkan pelayanan antenatal care pada ibu hamil dengan memberikan edukasi terkait Covid-19.
Post-Secondary Education Options and the Rate of Persistence to Graduate Studies: Trend in a Minnesota Higher Institution between 2007 and 2019
Authors: Akinde Oluwatoyin Adenike 
Published: March 2022

Earlier research on Post-Secondary Enrollment Options (PSEO) has produced insights on policies, with emphasis on legislating the enrollment of high-school students who are taking college credits through the program. Previous studies have focused on what are considered impediments to the program, improving governance, and assessment, with a view on academic performance in undergraduate programs, however, with limited attention to higher learning and lifelong learning. Based on the literature, PSEO has served as an early pathway to higher education for academically advanced students, which has also served as a good form of transition to higher education. Despite this, so much is unknown about various aspects of the success of the program. This current study focus specifically on the rate of PSEO participant who enters a graduate and or professional degree program after earning an undergraduate degree, based on admittance in a Mid-western private liberal art university between 2007 to 2019. The result shows that 13% are likely to persist to earn a graduate or professional degree after completing their undergraduate degree.