bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perbedaan Kemampuan Pemecahan Masalah dan Komunikasi Matematis antara Pembelajaran TPS dan NHT
Authors: Simamora Minta Ito , Rizqi Nur Rahmi 
Published: March 2022

Tujuan penelitian ini untuk menyelidiki perbedaan: (1) kemampuan pemecahan masalah matematis antara siswa yang menerima pembelajaran kooperatif tipe TPS dan NHT, (2) kemampuan komunikasi matematis antara siswa yang mendapat pembelajaran kooperatif tipe TPS danNHT, dan (3) interaksi yang signifikan antara siswa yang diberi pembelajaran matematika (TPS, NHT) dengan kemampuan awal (tinggi, sedang, rendah) terhadap kemampuan pemecahan masalah matematis dan komunikasi matematis siswa. Sampel eksperimen ini dilakukan di kelas VIII-3 dan VIII-4, masing-masing sebanyak 25 siswa. Instrumen yang digunakan menguji kemampuan pemecahan masalah matematis dan komunikasi matematis yaitu tes. Teknik analisis data pada penelitian ini adalah menggunakan Uji analisis varian dua jalur (ANAVA). Hasil penelitian ini adalah diperoleh rata-rata tes kemampuan pemecahan masalah matematis kelas TPS 28,64 dan rata-rata tes kemampuan pemecahan masalah matematis kelas NHT 22,20. Rata-rata tes kemampuan komunikasi matematis kelas TPS 13,40 dan Rata-rata tes kemampuan komunikasi matematis kelas NHT 11,72. Setelah dilakukan uji-t diperoleh t hitung pada kemampuan pemecahan masalah matematis 4,546 dan t hitung pada kemampuan komunikasi matematis 1,916.

The purpose of this study is to investigate the differences in: (1) math problem solving ability between students receiving TPS and NHT cooperative learning method, (2), students receive cooperative learning in mathematics through TPS and NHT, and (3) having meaningful interactions. between students who acquire mathematics (TPS, NHT) and their initial capacity (high, medium, low) in math problem solving and communication skills. The sample of this exeperiment research has already been conducted in the classes of VIII3 and VIII 4, that involved 25 students in each classes, The instruments used to test math problem solving and communication skills is a quiz. The data analysis technique in this study used two-way analysis of the test of variance (ANAVA). The average problem-solving ability test of TPS class is 28.64 and the average ability test of NHT class is 22.20. The average Mathematical Communication Aptitude test for the TPS class is 13.40 and the average Mathematical Communicative Ability test for the NHT class is 11.72. After conducting the test, people got a score of 4,546 for math problem solving ability and 1,916 for math communication ability.
Pola Hubungan Etnik di Wilayah Perkotaan: Sebuah Studi di Kelurahan Tanjung Hulu Pontianak Kalimantan Barat
Authors: Arkanudin Arkanudin , Rupita Rupita , Batualo Ignasia Debby 
Published: March 2022

Tujuan dari penelitian ini adalah mengetahui hubungan etnis dan sosial dalam konteks masalah hubungan sosial dalam bidang ekonomi, agama, kekerabatan, dan masyarakat di Kelurahan Tanjung Hulu Kecamatan Pontianak Timur. Metode yang digunakan adalah metode deskriptif analitis dengan pendekatan kualitatif. Deskripsi analitis digunakan untuk menggambarkan keadaan masyarakat yang diteliti. Pendekatan kualitatif menekankan pada data kualitatif. Hasil penelitian menunjukkan bahwa orang Melayu jauh lebih banyak daripada pendatang, tetapi mereka belum memenuhi syarat untuk mendominasi budaya lain. Mereka juga tidak unggul dalam bidang ekonomi. Hal ini terlihat ketika perekonomian umumnya didominasi oleh etnis pendatang seperti Madura, Padang, dan Tionghoa. Hubungan sosial bidang kekerabatan fokus pada pernikahan dalam satu suku. terutama dalam memilih pasangan masih menginginkan pasangan dari sukunya, namun perkawinan antar suku sering terjadi. Hubungan sosial dalam bidang agama tampak sangat toleran antarpemeluk agama yang berbeda. Hubungan sosial dalam kehidupan masyarakat antarkelompok etnis berjalan cukup harmonis, yang berbeda berusaha untuk hidup berdampingan, mempromosikan dan menjaga keharmonisan, terlepas dari asal etnis atau budaya. Mereka cocok dengan masyarakat tempat mereka tinggal.

The purpose of this study was to determine ethnic and social relations in the context of social relations problems in the fields of economy, religion, kinship and society in Tanjung Hulu Village, East Pontianak District. The method used is descriptive analytical qualitative method with a qualitative approach. Analytical descriptions are used to describe the state of the community being studied as it is. The qualitative approach emphasizes research methods that use qualitative data. The results show that there are far more Malays than immigrants, but they are not yet qualified to dominate other cultures. They also do not excel in the economic field. This can be seen when the economy is generally dominated by ethnic immigrants such as Madurese, Padang, and Chinese. Social relations in the field of kinship, especially in choosing a partner, still want a partner from their tribe, but inter-tribal marriages often occur. The religious factor is still being considered. Social relations in the field of religion seem very tolerant between adherents of different religions. Social relations in peoples lives between different ethnic groups seek to coexist, promote and maintain harmony, regardless of ethnic or cultural origin. In other words, they fit into the society they live in.
How to Get Daily Capital Gain in Covid-19 Pandemic Period? (Case study: Indonesia Stock Exchange)
Authors: Harahap Kartini 
Published: March 2022

The purpose of this research is to find out how to obtain daily capital gains in the midst of the Covid-19 pandemic using the day trade strategy and the Stochastic Oscillator as a technical indicator case study of stocks in the telecommunications industry sector. This research is descriptive in nature and uses secondary data, namely: data on daily stock prices and hourly charts, per 10 minutes on the stock price movements of PT Telekomunikasi Indonesia Tbk (TLKM) and PT Smartfren Telecom Tbk (FREN). The result of this study are finding TLKM and FREN stocks as the right stocks for day trade, day trading from the market opening or in the morning and completing transactions during the day because the volume of shares decreases reflected in the volume of TLKM shares, but not on FREN shares. Stochastic Oscillator indicator can be used to obtain daily capital gains at TLKM and FREN stocks; (a) the red box area is the best momentum for "sell" positions, the green box area is the best momentum for "buy" positions. (b) the arrow in the red box there is a% K line that crosses% D upwards/ downwards, indicating a sell/buy signal at TLKM and during this period the FREN shares did not have the momentum to sell. The results of this study are expected to give consideration to investors not to panic selling and provide knowledge about how to earn daily profits on the stock market during the Covid-19 Pandemic with a simple method so that the Indonesian capital market remains excited amid the Covid-19 Pandemic.
The Effect of Environment Complexity and Resources on the Performance of SMEs Mediated By Business Strategy (Survey on Kasongan Pottery SMEs In Bantul Regency)
Authors: Wuryaningrum Nuruita , Sabihaini Sabihaini , Yudhiantoro Danang 
Published: March 2022

This study aims to analyze the effect of environmental complexity and resources on the performance of SMEs mediated by business strategy in Kasongan pottery SMEs. The population in this study were all SMEs pottery handicrafts in the Kasongan pottery center in Kasihan District, Bantul Regency, Yogyakarta. Total of 61 questionnaires have been returned and processed. The data analysis technique used was Partial Least Square (PLS) through SmartPLS 3.3.2 software. The research shows that environmental complexity has a positive and significant effect on performance of SMEs, resources have a positive and significant effect on performance of SMEs, environmental complexity has a positive and significant effect on business strategy, resources have a positive and significant effect on business strategy, and business strategy has a positive and significant effect on performance of SMEs. Also, it is found that environmental complexity has a positive and significant indirect effect on performance of SMEs through business strategy and resources have a positive and significant indirect effect on performance of SMEs mediated by business strategy. Keywords:Performance of SMEsEnvironment ComplexityResourcesBusiness strategy
Immunomodulation as a Protective Strategy in Chronic Otitis Media
Authors: Leichtle Anke , Kurabi Arwa , Leffers David , Därr Markus , Draf Clara Sophia , Ryan Allen Frederic , Bruchhage Karl-Ludwig 
Published: March 2022

IntroductionMajor features of the pathogenesis in otitis media, the most common disease in childhood, include hyperplasia of the middle ear mucosa and infiltration by leukocytes, both of which typically resolve upon bacterial clearanceviaapoptosis. Activation of innate immune receptors during the inflammatory process leads to the activation of intracellular transcription factors (such as NF-κB, AP-1), which regulate both the inflammatory response and tissue growth. We investigated these leading signaling pathways in otitis media using mouse models, human samples, and human middle ear epithelial cell (HMEEC) lines for therapeutic immunomodulation.MethodsA stable otitis media model in wild-type mice and immunodeficient KO-mice, as well as human tissue samples from chronic otitis media, skin from the external auditory canal and middle ear mucosa removed from patients undergoing ear surgery, were studied. Gene and protein expression of innate immune signaling molecules were evaluated using microarray, qPCR and IHC.In situapoptosis detection determined the apoptotic rate. The influence of bacterial infection on immunomodulating molecules (TNFα, MDP, Tri-DAP, SB203580, Cycloheximide) in HMEEC was evaluated. HMEEC cells were examined after bacterial stimulation/inhibition for gene expression and cellular growth.ResultsPersistent mucosal hyperplasia of the middle ear mucosa in chronic otitis media resulted from gene and protein expression of inflammatory and apoptotic genes, including NODs, TNFα, Casp3 and cleaved Casp3. In clinical chronic middle ear samples, these molecules were modulated after a specific stimulation. They also induced a hyposensitive response after bacterial/NOD-/TLR-pathway double stimulation of HMEEC cellsin vitro. Hence, they might be suitable targets for immunological therapeutic approaches.ConclusionUncontrolled middle ear mucosal hyperplasia is triggered by TLRs/NLRs immunoreceptor activation of downstream inflammatory and apoptotic molecules.
Paleoclimate Records of the Middle Okinawa Trough Since the Middle Holocene: Modulation of the Low-Latitude Climate
Authors: Liu Lei , Guan Hongxiang , Xu Lanfang , Sun Zhilei , Wu Nengyou 
Published: March 2022

The ubiquity of glycerol dibiphytanyl glycerol tetraethers (GDGTs) and their temperature sensitivity make them one of the most effective tools for paleoclimate reconstruction. High- and low-latitude climates influence the Okinawa Trough (OT). It receives diverse inputs from the East China Sea, the western Pacific, and the Kuroshio Current, providing good conditions for paleoclimate studies. Here, isoprenoid GDGTs (isoGDGTs), branched GDGTs, and hydroxylated GDGTs (OH-GDGTs) were studied to reconstruct the sea surface temperature (SST) of the central OT for the past 8.2 kyr using the tetraether index of 86 carbon atoms at low latitudes (TEXH86) and the ring index of OH-GDGTs (RI-OH). The GDGT-0/crenarchaeol ratios ranged from 0.39 to 0.98. The branched and isoprenoid tetraether index and the methane index values were lower than 0.1 and 0.5, respectively, indicating that the isoGDGTs were mainly derived from marine Thaumarchaeota and that TEXH86 could be used to reconstruct the paleotemperatures. The TEXH86 SSTs ranged from 21.6 to 27.2°C during 8.2 kyr. The overall range of TEXH86 SSTs is close to the UK’37 SST of the middle OT and reflects the mean annual SST. In contrast, RI-OH temperatures varied from 17.4 to 26.0°C, showing a lower trend than TEXH86 SSTs. The core top RI-OH temperature is 24.1°C, in line with the mean annual seawater temperature at 40 m (24.2°C) in the study area, which likely reflects the subsurface temperature in this case. The small overall warming trend of TEXH86 SSTs agrees with the increasing intensity of the Kuroshio Current during the last 8.2 kyr, indicating that the SST evolution is governed by the Kuroshio Current that transports heat from the western tropical Pacific. The decreasing temperature differences between TEXH86 and RI-OH and between UK’37 and RI-OH showed increased mixing of the upper water column, which was in good accordance with the increasing low-latitude winter insolation decoupling from the East Asian summer monsoon. The cold event that occurred at 7.4–6.6 kyr was magnified (∼5°C) at the TEXH86 and RI-OH temperatures and possibly caused by tephra’s significant input (∼7.3 kyr).
Case Report: A New Peroxisome Proliferator-Activated Receptor Gamma Mutation Causes Familial Partial Lipodystrophy Type 3 in a Chinese Patient
Authors: Chen Xi , Ma Zhiqiang , Chen Peng , Song Xiuli , Li Weihua , Yu Xuefeng , Xie Junhui 
Published: March 2022

PurposeFamilial partial lipodystrophy type 3 (FPLD3) is an autosomal dominant disease. Patients typically present with loss of adipose tissue and metabolic complications. Here, we reported a Chinese FPLD3 patient with a novel PPARG gene mutation.MethodsA 16-year-old female patient and her relatives were assessed by detailed clinical and biochemical examinations. Sequencing was performed by using the extracted DNA. Moreover, we identified FPLD3 patients from previous studies, and according to the protein region affected by the gene mutation. We divided the patients into the DNA-binding domain (DBD) group or the ligand-binding domain (LBD) group, and compared the clinical features between the two groups.ResultsWe identified a novel gene mutation affecting the LBD of PPARγ c.929T &gt; C (p.F310S). This mutation leads to the substitution of a phenylalanine by a serine. In our case, subcutaneous fat was significantly diminished in her face, hips and limbs. The patient was also presented with insulin resistance, diabetes mellitus, hypertriglyceridemia, fatty liver, liver dysfunction, albuminuria and diabetic peripheral neuropathy. After literature review, a total of 58 FPLD3 patients were identified and we found no difference in clinical features between the DBD group and LBD group (all P &gt; 0.05).ConclusionsA Chinese FPLD3 patient with a novel PPARG gene mutation is described. Our case emphasized the importance of physical examination and genetic testing in young patients with severe metabolic syndromes.
Effect of Direct Bilirubin Level on Clinical Outcome and Prognoses in Severely/Critically Ill Patients With COVID-19
Authors: Chen Wensen , Liu Hanting , Yang Gang , Wang Wei , Liu Qiongfang , Huang Chaolin , Zou Zhuoru , Liu Yun , Zhuang Guihua , Zhang Lei 
Published: March 2022

ObjectivesWe aimed to investigate how changes in direct bilirubin (DBiL) levels in severely/critically ill the coronavirus disease (COVID-19) patients during their first week of hospital admission affect their subsequent prognoses and mortality.MethodsWe retrospectively enrolled 337 severely/critically ill COVID-19 patients with two consecutive blood tests at hospital admission and about 7 days after. Based on the trend of the two consecutive tests, we categorized patients into the normal direct bilirubin (DBiL) group (224), declined DBiL group (44) and elevated DBiL group (79).ResultsThe elevated DBiL group had a significantly larger proportion of critically ill patients (χ2-test, p &lt; 0.001), a higher risk of ICU admission, respiratory failure, and shock at hospital admission (χ2-test, all p &lt; 0.001). During hospitalization, the elevated DBiL group had significantly higher risks of shock, acute respiratory distress syndrome (ARDS), and respiratory failure (χ2-test, all p &lt; 0.001). The same findings were observed for heart damage (χ2-test, p = 0.002) and acute renal injury (χ2-test, p = 0.009). Cox regression analysis showed the risk of mortality in the elevated DBiL group was 2.27 (95% CI: 1.50–3.43, p &lt; 0.001) times higher than that in the normal DBiL group after adjusted age, initial symptom, and laboratory markers. The Receiver Operating Characteristic curve (ROC) analysis demonstrated that the second test of DBiL was consistently a better indicator of the occurrence of complications (except shock) and mortality than the first test in severely/critically ill COVID-19 patients. The area under the ROC curve (AUC) combined with two consecutive DBiL levels for respiratory failure and death was the largest.ConclusionElevated DBiL levels are an independent indicator for complication and mortality in COVID-19 patients. Compared with the DBiL levels at admission, DBiL levels on days 7 days of hospitalization are more advantageous in predicting the prognoses of COVID-19 in severely/critically ill patients.
Self-Reported Anxiety and Depression in a Monocentric Cohort of Patients With Systemic Lupus Erythematosus: Analysis of Prevalence, Main Determinants, and Impact on Quality of Life
Authors: Elefante Elena , Tani Chiara , Stagnaro Chiara , Signorini Viola , Lenzi Beatrice , Zucchi Dina , Trentin Francesca , Carli Linda , Ferro Francesco , Mosca Marta 
Published: March 2022

Aims of the studyTo analyze the prevalence of self-reported anxiety and depression in a monocentric cohort of patients with Systemic Lupus Erythematosus (SLE); to study the main determinants and the impact on quality of life (QoL).MethodsA cross-sectional observational study including adult outpatients with SLE. Demographic and clinical data were analyzed: indices of disease activity (SELENA-SLEDAI); damage (SLICC-DI); comorbidities and concomitant therapies. The definitions for remission (DORIS) and “Lupus Low Disease Activity State” (LLDAS) were applied. At enrollment, each patient completed the following questionnaires: SF-36, FACIT-Fatigue, Lupus Impact Tracker (LIT), Systemic Lupus Activity Questionnaire (SLAQ), and the Hospital Anxiety and Depression Scale (HADS) in order to self-assess anxiety and depression symptoms. The Student t-test and Chi2 tests were conducted for univariate analysis. The Spearman test was used for linear correlation between continuous data. Multivariate analysis was performed by multiple linear and logistic regression.ResultsOne hundred fifty-four consecutive patients with SLE were enrolled, the majority female and Caucasian with a mean age = 43.3 ± 13.7 years. 79.9% were in LLDAS or remission. 36.4% had a SDI &gt; 1. 13.7% of patients had concomitant fibromyalgia. 37.4% had symptoms indicating anxiety and 25% of depression according to the HADS questionnaire. In the multivariate analysis, patients with active disease were significantly more anxious and depressed (p &lt; 0.01) compared to patients in LLDAS or remission. Fibromyalgia and older age were independently associated with anxiety and depression, respectively (p &lt; 0.05). Active skin involvement was significantly linked to depression (p &lt; 0.05). Higher scores on the HADS questionnaire (higher levels of anxiety and depression) were found to be significantly linked to patients’ perception of higher disease activity and worse quality of life, irrespective of disease activity, age and fibromyalgia.ConclusionSymptoms of anxiety and depression are frequent in SLE patients, including outpatients with mild/moderate disease. Such symptoms have a significant negative impact on QoL and perception of disease activity, regardless of other factors. Moreover, disease activity, advanced age and fibromyalgia appear to be significantly linked to mood disorders. Assessing symptoms of the anxious-depressive spectrum in patients with SLE could lead to improvement in patients’ perception of health status and quality of life.
Association of Dietary and Lifestyle Inflammation Score With Cardiorespiratory Fitness
Authors: Farazi Mena , Jayedi Ahmad , Noruzi Zahra , Janbozorgi Nasim , Djafarian Kurosh , Shab-Bidar Sakineh 
Published: March 2022

ObjectiveWe aimed to assess the potential association of dietary (DIS) and lifestyle inflammation score (LIS) and their joint association (DLIS) with cardiorespiratory fitness (CRF) in Tehranian adults.DesignThe present study was designed cross-sectional.ParticipantsA total of 265 males and females aged 18–70 years (mean ± SD: 36.9 ± 13.3) were entered in the present cross-sectional study. Eligible participants were healthy men and women who were free of medications and had no acute or chronic infection or inflammatory disease.MeasuresThe DIS was calculated by the use of data from 18 anti- and pro-inflammatory dietary components, and the LIS by three non-dietary components including physical activity, smoking status, and general adiposity, with higher scores indicating a more pro-inflammatory diet and lifestyle, respectively. The DLIS was calculated by summing the DIS and LIS. CRF was assessed by the Bruce protocol and VO2 max was measuredas the main variable of CRF. The odds ratio (OR) and 95% confidence interval (CI) of CRF across tertiles of the DIS, LIS, and DLIS were estimated by logistic regression analysis with considering age, gender, energy intake, marital and education status, and occupation as confounders.ResultsThe DLIS ranged from −2.10 to 0.38 (mean ± SD: −1.25 ± 0.64). In the model that controlled for all variables, the ORs of CRF for the second and third tertiles of the DLIS as compared to the first tertile were 0.42 (95%CI: 0.20, 0.90) and 0.12 (95%CI: 0.05, 0.32), respectively (P-trend &lt; 0.001). There was a strong inverse association between the LIS and CRF (ORthirdvs.firsttertile: 0.12, 95%CI: 0.05, 0.32). There was no association between DIS and CRF.ConclusionThe present study examined the joint association of inflammation-related lifestyle behaviors with CRF and found a strong inverse association between a pro-inflammatory lifestyle with CRF. We did not find any association between dietary inflammatory properties with CRF. Future studies should address the relationship between the inflammatory potential of the diet and CRF.