bluuebunny/crossref_metadata_2025_split huggingface dataset:
An exploratory identification of biological markers of chronic musculoskeletal pain in the low back, neck, and shoulders
Authors: Djade Codjo Djignefa , Diorio Caroline , Laurin Danielle , Dionne Clermont E. 
Published: April 2022

Objectives
This study was an in-depth exploration of unique data from a nationally representative sample of adults living in the United States to identify biomarkers associated with musculoskeletal pain.

Methods
We performed secondary analyses of 2003–2004 NHANES data. After a first screening of 187 markers, analyses of 31 biomarkers were conducted on participants aged ≥20 years identified in all counties using the 2000 Census Bureau data (n = 4,742). To assess the association of each biomarker with each pain outcome (acute, subacute and chronic low back, neck, and shoulder pain), analyses were carried out using multivariable logistic regression with adjustments for sex, age and body mass index. Biomarkers were considered as continuous variables and categorized at the median of their distributions.

Results
Pain at any site for ≥24 hours during the past month was reported by 1,214 participants. Of these, 779 mentioned that the pain had lasted for ≥3 months (“chronic pain”). α-carotene, ascorbic acid, β-carotene, mercury and total protein had a statistically significant, inverse association with ≥2 chronic pain sites. Acrylamide, alkaline phosphatase, cadmium, cotinine, glycidamide, homocysteine, retinol, triglycerides and white blood cell count were positively associated with ≥2 chronic pain sites. Few biological markers were associated with acute and subacute pain.

Conclusions
This study identified some biomarkers that were strongly and consistently associated with musculoskeletal pain. These results raise new hypotheses and could have tremendous implications for advancing knowledge in the field. Research on musculoskeletal pain needs to put more effort on the biological dimension of the biopsychosocial model of pain.
Country of birth as a potential determinant of inadequate antenatal care use among women giving birth in Brussels. A cross-sectional study
Authors: Schönborn Claudia , Castetbon Katia , De Spiegelaere Myriam 
Published: April 2022

Background
One of the mechanisms explaining perinatal health inequalities could be inadequate antenatal care among some immigrant groups. Few European studies compared antenatal care use between different groups of immigrants taking into account individual characteristics. This research investigates the associations of three birth regions with the use of antenatal care, by also considering socioeconomic and migration-related determinants.

Methods
We included 879 mothers born in Belgium, North Africa, and Sub-Saharan Africa, and interviewed them in four Brussels hospitals after they gave birth, using an adapted version of the Migrant-Friendly Maternity Care Questionnaire. We additionally collected clinical data from hospital records. We carried out descriptive analyses and ran univariate and multivariable logistic regression models to estimate the associations of socioeconomic and migration characteristics with a) late start of antenatal care and b) less than minimum recommended number of consultations.

Results
The vast majority of women in this study had adequate care in terms of timing (93.9%), frequency of consultations (82.2%), and self-reported access (95.9%). Region of birth was an independent risk factor for late initiation of care, but not for infrequent consultations. Women born in Sub-Saharan Africa were more prone to accessing care late (OR 3.3, 95%CI 1.5–7.7), but were not more at risk of infrequent consultations. Women born in North Africa, had similar adequacy of care compared to the Belgium-born population. The three groups also differed in terms of socioeconomic profiles and socioeconomic predictors of antenatal care use. Housing type, professional activity, and health insurance status were important predictors of both outcomes.

Conclusions
This study showed that the region of birth was partly associated with adequacy of care, in terms of initiation, but not number of consultations. Further dimensions of adequacy of care (content, quality) should be studied in the future. Socioeconomic factors are also key determinants of antenatal care use.
Homo Eroticus: Cinema, identità maschile e società italiana nella rivista ‘Playmen’, Gabriele Rigola (2021)
Authors: Scarcelli Cosimo Marco 
Published: April 2022

Review of: Homo Eroticus: Cinema, identità maschile e società italiana nella rivista ‘Playmen’, Gabriele Rigola (2021)
Soveria Mannelli: Rubettino, 187 pp.,
ISBN 978-8-84986-538-7, p/bk, €14.00
Viragoes, Spermatophagy, and Racial Degeneration: Cultural Contraventions in Josephine Butler’s Meditations on the Levite’s Woman
Authors: Lee Bernon 
Published: April 2022

Abstract
The exponents of fin-de-siècle literary artistry painted New Woman a lascivious man-eating beast whose emasculating initiatives would check Western European ascent to civilization’s apogee. Unfettered by tradition, her intemperate spirit, blind to the fine(r) things of a “higher” cultural order, would return humankind to a primitive state. Literature and science, it seems, conspire along these lines to curb Late Victorian sexual-social anxiety. In this article, I situate Josephine Butler’s reading of the story of the Levite and his woman (Judges 19) in the stream of a broader challenge to the literary sensibilities of the time. Butler’s voluminous writings from the latter half of the nineteenth century brought a Christian acumen to bear upon a sustained critique of the androcentric and misogynistic persuasion at the heart of a cultural consensus on women’s character and sexuality. Her contention through an astute consideration of the Judges story is that a pervasive masculine animus of lust and rapine is the root of a crippling decline that is moral and religious, not strictly devolutionary. Yet, Butler’s favor for the tropes of the time—female salaciousness, mangled bodies, diseased members, and national degeneration—is resonant of language in the service of a broader consternation respecting the revisionary social-sexual movements afoot. Butler’s co-option of the cultural cadences in currency, I contend, is symptomatic of a shared ethos—that European dominance and splendor is the high-water mark of human achievement. In this respect, I propose, Butler’s critique of fin-de-siècle literary and scientific discourse is ambivalent. In rejecting and replacing the faddish cult of the inordinate woman with the scourge of the intemperate man, she stays, still, within the bounds of a British (and European) masterly optic on the non-European world.
Diagnosis of congenital infections in premature, low-birthweight newborns with intrauterine growth restriction caused by cytomegalovirus (CMV), herpes simplex virus (HSV), Parvo-B 19, and Zika virus: a systematic review
Authors: Lino Janaina F. , Diniz Lilian M. O. , Rezende Larissa G. , Costa Victoria F. T. , Romanelli Roberta M. C. 
Published: April 2022

Abstract

Objectives
To identify the prevalence of viral congenital infections in newborns classified as premature, low-birthweight, small for gestational age or intrauterine growth restriction.

Methods
The definition considered for selecting papers were: P as newborns younger than 28 days; V as low-birthweight, prematurity and intrauterine growth restriction; O as frequency of congenital infections with Cytomegalovirus, Parvovirus B19, Herpes Simplex, and Zika virus. The research was performed using EMBASE, LILACS, SCOPUS and MEDLINE databases, with no limitations on date and language.

Results
Eight studies were included. Manuscripts including Herpes Simplex, Zika virus or Parvovirus B19 did not fulfill the defined criteria. A wide variation in the frequency of CMV congenital infection (0–4.8%) was found, which might be attributed to regional and methodological differences between investigations.

Conclusions
Newborn characteristics associated with CMV congenital infections may direct investigations towards these patients with a higher probability of infection. However, as data are controversial, studies concerning screening of infection are important to define recommendations of diagnosis.
Crystal structure of (Z)-4-[(p-tolylamino)(furan-2-yl)methylene]-3-phenyl-1-1-p-tolyl-1H-phenyl-1H-pyrazol-5(4H)-one, C28H23N3O2
Authors: Wei Wei , Wu Qiong , Jin Tong-Yin , Zhang Ya-Zhai , Xuan Zhao-Kun , Zhang Heng-Qiang 
Published: April 2022

Abstract
C28H23N3O2, triclinic,

P

1
‾

$P\overline{1}$

(no. 2), a = 7.6590(7) Å, b = 11.8598(12) Å, c = 12.4954(14) Å, α = 92.027(9)°, β = 99.837(9)°, γ = 93.597(8)°, V = 1114.9(2) Å3, Z = 2, R

gt
(F) = 0.0508, wR

ref
(F
2) = 0.1317, T = 293(2) K.
The The Associative Influence of Phonetic Nonce Words (Occasionalisms) in Modern Ukrainian Poetical Discourse
Authors: Hryshko Yuliia 
Published: April 2022

The article presents the results of three linguistic associative experiments. The purpose of this research is to determine the influence of specific linguistic units – phonetic nonce words (occasionalisms) – on the perception of modern Ukrainian poetical discourse by addressees (readers). As stimuli for linguistic analysis of phonetic occasional units in modern Ukrainian poetical discourse used the most frequent phonetic nonce words in their graphic actualization (total 16 different stimuli). The three experimentally groups of respondents include 105 students of three Poltava high schools. A result of these experiments are 1684 reactions, among which 1146 (68%) – positive, 300 (18%) – negative, 238 (14%) – neutral. The lowest per cent of neutral reactions is motivated because phonetic nonce words are power intensifiers for the expressiveness of sound background in poetical discourse. The phonetic nonce words positively influence the perception of modern verbal discourse by addressees. The special role in decoding of sound information belongs to acoustic-articulator characteristics of vowels and consonants.
The Response of the Catholic Church in the United States to Offences of Sexual Abuse of Minors Committed by Clerics Based on the Example of the Diocese of Fairbanks
Authors: Lewandowski Paweł 
Published: April 2022

Offences of sexual abuse committed by clerics, which are a grave sin, cause physical, mental and spiritual harm to their victims and greatly harm the community of the faithful. In order to prevent such situations from happening anymore, it is necessary to take great responsibility for minors, for people who habitually have an imperfect use of reason and for people to whom the law recognizes equal protection. This concern may be considered an indispensable part of the mission entrusted to the Church, which, as a community of the faithful, strives for the salvation of every human being and for the common good of the community in which it carries out its mission. The answer to how to accomplish this task and how to bring church communities out of the deep crisis caused by sexual abuse of clergy comes from the Catholic Church in the United States, including the Diocese of Fairbanks.
The bishop’s responsibility for his presbyterate in the context of sexual offences committed by priests
Authors: Majer Piotr 
Published: April 2022

The aim of this paper is to answer the question: How should the bishop act towards his presbyterate so that its members would not commit sexual offences, particularly the most serious ones? The following issues are presented: the relationship between a bishop and his presbyterate, the bishop’s responsibility for the admission of proper candidates to ordination, the assignment of offices and functions in the diocese, the bishop’s obligation to watch over the discipline of the clergy, the bishop’s responsibility for granting the faculty of hearing the confessions.
Sexual abuse of minors by clergy in cinematography: unrecognized signs of the times
Authors: Lis Marek 
Published: April 2022

Contemporary theologians apply the historic notion of loci theologici also to media and film. Films that show the Church in a critical way are also theologically significant. Therefore, one should be aware of the appearance of documentaries and feature films, which raise the issue of sexual abuse against the youngest (paedophilia) also in the Church. The article presents the most important films, produced since the end of the 20th century, whose authors present the crime of paedophilia, its victims, the mechanisms leading to its concealment and silence not only in the Church, but also in the media and society. Films about paedophilia, which are a recognisable voice of victims in the public space, a cry for truth and justice, can also be useful tools for media education.
Contribution of the COVID-19 pandemic to the prognosis of patients with class III-IV heart failure
Authors: Vaisberg A. R. , Fomin I. V. , Polyakov D. S. , Omarova Yu. V. 
Published: April 2022

Aim. To study the survival of patients with New York Heart Association (NYHA) class IIIV heart failure (HF) after a coronavirus disease 2019 (COVID-19) and compare it with a group of similar patients without COVID-19, both during and before the pandemic.Material and methods. A sample of 810 patients with HF of any class was created, who were treated in the HF center at the City Clinical Hospital № 38 in Nizhny Novgorod for the period from March 2019 to March 2020. Patients with NYHA class HF III-IV (n=263) were selected from this sample. The diagnosis was confirmed by echocardiography and chest radiography. At the time of discharge, the 6-minute walk test was <300 meters, while the level of N-terminal pro-brain natriuretic peptide — >300 pg/ml. The group was analyzed from March 2019 to December 2021 with the definition of all-cause mortality depending on prior COVID-19.Results. During 520-day follow-up, 30,8% of NYHA class III-IV patients died, while 16,0% of patients underwent COVID-19, of which 79,25% of patients died during this period. Mortality among patients without prior COVID-19 was 23,3% (p<0,001). The 30-day mortality among those with COVID-19 was 50,0%, while for the year, this parameter was 71,4% (p<0,001). Among patients without COVID-19 and with class III-IV HF, 4,64% died in the first 30 days, and 20,7% of patients died during the year (p<0,001). The results obtained were compared with the data from the EPOCHA-CHF program from 2002 to 2017.Conclusion. Mortality among patients with class III-IV HF after COVID-19 was 3,5 times higher compared with those with class III-IV HF without prior COVID-19. During the COVID-19 pandemic, the mortality rate among patients with class III-IV HF without COVID-19 increased by 2,09 times compared with the pre-pandemic period.
Impact of optimal therapy for noncommunicable diseases on the course and outcome of COVID-19 inpatients
Authors: Frolova I. A. , Tarlovskaya E. I. , Romanov S. V. , Abaeva O. P. , Frolov A. A. 
Published: April 2022

Aim. To carry out a comparative analysis of the impact of optimal and suboptimal therapy for noncommunicable diseases (NCDs) at the prehospital stage on the severity and outcomes of coronavirus disease 2019 (COVID-19).Material and methods. The study included 158 patients hospitalized with a diagnosis of COVID-19 and having one or more concomitant NCDs. Patients were divided into two groups depending on the quality of initial therapy for NCDs: group 1 — patients receiving treatment that does not meet modern clinical guidelines, taking drugs not regularly or not taking them at all (n=100; 63%), and group 2 — patients receiving treatment in accordance with current clinical guidelines, taking regularly prescribed therapy (n=58; 37%). The primary endpoint was inhospital death, while secondary endpoints — duration of fever, length of intensive care unit (ICU) stay, length of hospital stay.Results. Inhospital mortality was significantly higher in the 1st group of patients compared with the 2nd group (18,0% vs 1,7%, p=0,002). Analysis of secondary endpoints revealed that patients of the 1st group (nonoptimal therapy), in comparison with the 2nd group (optimal therapy), had significantly longer period of fever (10 [7; 12] vs 9 [7; 10] days, p=0,03), longer ICU (0 [0; 3] vs 0 [0; 0] days, p<0,001) and hospital stay (10 [8; 14] vs 8 [7; 11] days, p=0,001).Conclusion. Patients who received standard NCD therapy before admission to the infectious disease hospital, in accordance with current clinical guidelines and who regularly take drugs, have a more favorable course of COVID-19 at the hospital stage and a lower inhospital mortality rate than patients with suboptimal therapy who are not adherent to treatment or not receiving drugs, but having indications for taking them.
Cytokine profile in hospitalized patients with COVID-19 of different severity
Authors: Grigoryeva N. Yu. , Sinichkina A. A. , Samoliuk M. O. , Kolosova K. S. , Korolеva E. V. , Kondakova E. V. , Vedunova M. V. 
Published: April 2022

Analysis of cytokine profile markers in conjunction with the clinical manifestations of coronavirus disease 2019 (COVID-19) can provide valuable information about the pathogenetic manifestations of the disease, and therefore, in the future, determine drugs that affect the cytokine storm and have an anti-inflammatory effect.Aim. To identify correlations between the parameters of the developed cytokine profile and the clinical course in hospitalized patients with COVID-19 of different severity.Material and methods. The study included 70 hospitalized patients with a confirmed diagnosis of COVID-19, with a mean age of 58 [50;69] years, including 40 men (57%) and 30 women (43%). The average lung involvement according to computed tomography (CT) at admission was CT-2 [1;3]. Peripheral venous blood was taken at admission, which averaged 7 [6; 8] days from the symptom onset. Standard biochemical parameters were studied, as well as 47 cytokines and chemokines using the Multiplex system (Merck KGaA, Darmstadt, Germany).Results. Correlations was found between the lung involvement degree and the level of IL-8 (r=0,31, p<0,05), IL-15 (r=0,35, p<0,05), IL-18 (r=0,31, p<0,05), MCP-1 (r=0,36, p<0,05), MIG (r=0,50, p<0,05), TNF-α (r=0,41, p<0,05). An inverse correlation was also found in the level of blood oxygen saturation with the same indicators as follows: IL-8 (r=-0,27, p<0,05), IL-15 (r=-0,34, p<0,05), IL-18 (r=-0,31, p<0,05), MCP-1 (r=-0,40, p<0,05), MIG (r=-0,56, p<0,05), TNF-α (r=-0,45, p<0,05). IL-6 levels were significantly elevated in patients with severe COVID-19 (CT3, CT4), while no increase in IL-6 was observed in patients with moderate disease (CT1, CT2). It is noteworthy that in patients with diabetes, the highest values of IL-12, IL-9 were recorded.Conclusion. Hyperinflammatory syndrome in severe COVID-19 is manifested by high levels of IL-6, MIG, MDC, MCP-1, M-CSF, TNF-α, β, IL-8, IL-18, IL-15. With the CT-1 and CT-2, an increase in only the level of IL-18, IL-8 is noted. The identified patterns prove and make it possible to explain a number of systemic inflammatory changes that occur with COVID-19.
Epicardial adiposity as a predictor of COVID-19 severity in overweight and obese patients
Authors: Druzhilov M. A. , Kuznetsova T. Yu. 
Published: April 2022

Aim. To evaluate epicardial adiposity (EA), verified on the basis of epicardial adipose tissue (EAT) thickness according to echocardiography, as a possible predictor of the severity of coronavirus disease 2019 (COVID-19) course in overweight and obese patients in a retrospective analysis of data.Material and methods. We analyzed data on 165 patients (age, 45,2±4,7 years; men, 67,9%; body mass index, 31,4±3,5 kg/m2) who received outpatient or inpatient treatment for symptomatic COVID-19 in period from March 2020 to November 2021. Patients with diabetes, stage III-V chronic kidney disease and/ or cardiovascular disease were excluded from the analysis, with the exception of hypertension. EA was verified in the case of EAT thickness ≥4,8 mm for persons aged 35-45 years and ≥5,8 mm for persons 46-55 years old.Results. Patients with EA were characterized by higher hospitalization rates (52,2% vs 9,0%, p<0,01), moderate (56,5% vs 19,7%, p<0,01), high and very high severity (17,4% vs 3,3%, p<0,01) of disease course, lung injury of CT-1, CT-2 and CT-3 (32,6% vs 9,8% (p<0,01), 21,7% vs 7,4% (p<0,05), and 15,2% vs 2,5% (p<0,01), respectively), invasive ventilation (8,7% vs 0,8%, p<0,05) and C-reactive protein >10 mg/l (69,6% vs 21,3%, p<0,01). Predictors of hospitalization for symptomatic COVID-19 according to multivariate logistic regression analysis were age, fasting glycemia, systolic blood pressure, EAT thickness, which was characterized by the highest standardized regression coefficient among other predictors (0,384, p<0,001).Conclusion. EAT thickness may be one of the predictors of COVID-19 severity in overweight and obese patients. Persons with EA in the case of COVID-19 need more careful monitoring and measures to prevent severe course and complications.
The Lost Promise of Progressivism
Authors: Eisenach Eldon J. 
Published: April 2022

Long before the current calls for national service, civic responsibility, and the restoration of community values, the Progressives initiated a remarkably similar challenge. Eldon Eisenach traces the evolution of this powerful national movement from its theoretical origins through its dramatic rise and sudden demise, and shows why their philosophy still speaks to us with such eloquence.Eisenach analyzes how and why, between 1885 and World War I, progressive political ideas conquered almost every cultural and intellectual bastion except constitutional law and dominated every major national institution except the courts and party system. Progressives, he demonstrates, were especially influential as a force in American politics, higher education, and the media. They created wideranging professional networks that functioned like a "hidden national government" to counter a federal government they deeply distrusted. They viewed the university as their national "Church"—the main repository and disseminator of values they espoused. They established truly national journals for a national audience. And they drew much support from women's rights advocates and other highly vocal movements of their time.Permeated with an evangelical Protestant vision of the future, progressive thought was an integral part of the national discourse for nearly three decades. But, as Eisenach reveals, at the very moment of its triumph it disintegrated as both a coherent theory and a viable public doctrine. With the election in 1912 of Woodrow Wilson, the movement reached its peak, but thereafter lost its momentum and force. Its precipitous decline was accelerated by world war and by the rise of New Deal liberalism. By the end of the Depression it had disappeared as an influential player in American public life.In the decades that followed, the Progressive mantle went unclaimed. Conservatives blamed the Progressives for the rise of the welfare state and many liberals cringed at their theological and imperialist rhetoric. Eisenach, however, argues that we still have much to learn about and from the Progressives. By enlarging our understanding of their thought, we greatly increase our understanding of an America whose national institutions—political, cultural, educational, religious, professional, economic, and journalistic—are all largely the product of this thinking. In other words, their ideas are still very much with us.