bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nucleus of the lateral olfactory tract: A hub linking the water homeostasis‐associated supraoptic nucleus‐arginine vasopressin circuit and neocortical regions to promote social behavior under osmotic challenge
Authors: Hernández‐Pérez Oscar R. , Hernández Vito S. , Zetter Mario A. , Eiden Lee E. , Zhang Limei 
Published: September 2022

AbstractHomeostatic challenges may alter the drive for social interaction. The neural activity that prompts this motivation remains poorly understood. In the present study, we identify direct projections from the hypothalamic supraoptic nucleus to the cortico‐amygdalar nucleus of the lateral olfactory tract (NLOT). Dual in situ hybridization with probes for pituitary adenylate cyclase‐activating polypeptide (PACAP), as well as vesicular glutamate transporter (VGLUT)1, VGLUT2, V1a and V1b, revealed a population of vasopressin‐receptive PACAPergic neurons in NLOT layer 2 (NLOT2). Water deprivation (48 h, WD48) increased sociability compared to euhydrated subjects, as assessed with the three‐chamber social interaction test (3CST). Fos expression immunohistochemistry showed NLOT and its main efferent regions had further increases in rats subjected to WD48 + 3CST. These regions strongly expressed PAC1 mRNA. Microinjections of arginine vasopressin (AVP) into the NLOT produced similar changes in sociability to water deprivation, and these were reduced by co‐injection of V1a or V1b antagonists along with AVP. We conclude that, during challenge to water homeostasis, there is a recruitment of a glutamatergic‐multi‐peptidergic cooperative circuit that promotes social behavior.
Inclusión de migrantes en el sistema escolar chileno: estado del arte
Authors: Baeza-correa Jorge Benedicto , Bustos-Reyes Carlos Antonio , Guzmán-Droguett María Angélica , Imbarack-Dagach Patricia , Mercado-Guerra Javier Leonardo 
Published: September 2022

Este artículo da cuenta del estado del arte sobre la inclusión de migrantes en el sistema escolar chileno, y analiza tanto las tensiones no resueltas en las políticas educativas sobre la materia como las demandas que surgen para el logro de una educación inclusiva. Se trabajó a partir de una revisión sistemática, en la que se analizaron 53 artículos publicados entre 2015 y 2020, indexados en WoS, Scopus o Scielo. Se concluye la existencia de desafíos para la inclusión en el diseño de políticas, en la formación docente en interculturalidad, en la pertinencia curricular y en el abordaje de conductas de exclusión y racismo.
Cost Optimization and Energy Management of a Microgrid Including Renewable Energy Resources and Electric Vehicles
Authors: Hai Tao , Zhou Jincheng , Zain Jasni Mohamad , Vafa Saeid 
Published: September 2022

Abstract
Penetration of plug-in hybrid electric vehicles (PHEVs) is capable of alleviating numerous global environmental and energy challenges. Utilization of a significant number of PHEVs with significant capacity and control capabilities can increase electrical grid flexibility. However, optimum management of such vehicles with renewable energy sources (RESs) would be one of the primary difficulties needing to be investigated. In the form of a microgrid, the operation of substantial RESs’ and PHEVs’ penetration would be achieved when operating within a microgrid. The problem has been formulated and approached as a single-objective optimization model aiming to minimize the total cost of the grid-tied MG. The converged barnacles mating optimizer (CBMO) algorithm is deployed to tackle the problem. The derived results verify the desired performance of the method compared to well-established ones. In scenario 1, the CBMO method determines the MG operating costs that are lower than those given by some well-established methods including the genetic algorithm (GA), imperialist competitive algorithm (ICA), and particle swarm optimization (PSO). The cost computed by the CBMO is 263.632 €ct/day. Likewise, the values of cost for scenarios 2 and 3 utilizing the hybrid CBMO method are 300.1364 €ct/day and 336.2154 €ct/day, respectively. The findings confirm the usefulness of the proposed CBMO algorithm with an excellent convergence rate. Comparing the average solution time of the CBMO algorithm with those provided by other algorithms reveals the excellent performance of the CBMO method. The obtained results indicate that the mean simulation time of the suggested CBMO approach in the first case is 5.19 s, whereas the time required by the GA, PSO, and ICA is 12.92 s, 10.73 s, and 7.27 s, respectively.
Bi-Objective Surrogate Feasibility Robust Design Optimization Utilizing Expected Non-Dominated Improvement With Relaxation
Authors: Kania Randall J. , Azarm Shapour 
Published: September 2022

Abstract
Engineering design optimization problems often have two competing objectives as well as uncertainty. For these problems, quite often there is interest in obtaining feasibly robust optimum solutions. Feasibly robust here refers to solutions that are feasible under all uncertain conditions. In general, obtaining bi-objective feasibly robust solutions can be computationally expensive, even more so when the functions to evaluate are themselves computationally intensive. Although surrogates have been utilized to decrease the computational costs of such problems, there is limited usage of Bayesian frameworks on problems of multi-objective optimization under interval uncertainty. This article seeks to formulate an approach for the solution of these problems via the expected improvement Bayesian acquisition function. In this paper, a method is developed for iteratively relaxing the solutions to facilitate convergence to a set of non-dominated, robust optimal solutions. Additionally, a variation of the bi-objective expected improvement criterion is proposed to encourage variety and density of the robust bi-objective non-dominated solutions. Several examples are tested and compared against other bi-objective robust optimization approaches with surrogate utilization. It is shown that the proposed method performs well at finding robustly optimized feasible solutions with limited function evaluations.
Orientation Workspace Analysis and Parameter Optimization of 3-RRPS Parallel Robot for Pelvic Fracture Reduction
Authors: Lei Jingtao , Wang Jinhong 
Published: September 2022

Abstract
For parallel robots with general configuration, it is difficult to achieve the large rotation range requirement for pelvic fracture reduction. Application-based workspace optimization is important. In this paper, a 3-revolute-revolute-prismatic-spherical (3-RRPS) parallel robot with optimized parameters is studied, which can offer a large orientation workspace and relatively compact configuration. The inverse kinematics of the robot is analyzed by the closed-loop vector method. The cylindrical coordinate searching algorithm and boundary extraction method are adopted to calculate the orientation workspace. Defining the comprehensive branch length (CBL) to express robot’s compactness under the premise of satisfying the required orientation workspace. The genetic algorithm (GA) is adopted to optimize structural parameters of the robot with CBL as the objective function. The optimization results show that when the orientation angles of the moving platform are limited to not less than 28 deg, the CBL of the robot is 291 mm. Finally, the virtual prototype simulation verification shows that the orientation angles of the moving platform around x-axis and y-axis can reach ±28 deg, the orientation angle around z-axis can reach ±40 deg, which meets the requirements of the rotational range for pelvic fracture reduction surgery.
A Novel Multiscale Evaluation Metric for the Thermal Management of Data Centers
Authors: Zhu Jinchen , Zhang Kai 
Published: September 2022

Abstract
Tremendous burden is compelled on the energy consumption of data centers with the rapid development of information technology, and a healthy thermal environment is critical for improving the cooling efficiency of data centers. Furthermore, the thermal management of the data center is determined by the evaluation of its thermal environment. However, most of the existing evaluation metrics describe the thermal environment through a single scale, which cannot fully reflect the thermal performance of data centers at different scales. To simplify the evaluation of the thermal environment in data centers, a novel multiscale evaluation metric of the recirculation and hot spots index (RHSI) is proposed in this study. The numerical model of an operating data center is established and verified with the experiments on site. Then, the thermal environment of the data center is evaluated based on the RHSI and the existing metrics. Finally, the applicability of the RHSI is further discussed from different scales in detail. The results show that all bypass airflow, hot recirculation, and local hot spots can be derived from the proposed RHSI simultaneously by comparing with the evaluation metrics of supply heat index (SHI) and rack cooling indicator (RCI) at the room scale, β at the rack scale, and index of mixing (IOM) at the row scale. The proposed RHSI can provide a guiding significance for the thermal management of data centers.
Multi-Objective Optimization of a Bi-Metal High Temperature Recuperator for Application in Concentrating Solar Power
Authors: Bryan Jacob A. , Meek Aiden S. , Wang Hailei 
Published: September 2022

Abstract
In recent years, supercritical CO2 closed-cycle Brayton cycles have become a major candidate for future power cycle designs in concentrating solar power (CSP) applications, with many of these designs including partial recompression and regeneration to increase thermal efficiency. This increase in efficiency, combined with potential miniaturization of heat transfer equipment and turbomachinery, could help significantly decrease the cost of energy generated by CSP plants. The high-temperature recuperator in these designs plays an integral role in these cycles and must operate and high temperatures and pressures. Printed circuit heat exchangers (PCHEs) have become a leading technology for these recuperators due to their size advantage over traditional shell and tube heat exchangers. However, PCHEs for high-temperature recuperators often must be built from costly nickel alloys to accommodate the extreme operating conditions.
One potential solution to this cost problem is to tailor the material of the heat exchanger body to its operating conditions, rather than needing to choose a single material. This could be accomplished by using additive manufacturing to create a multi-material unibody heat exchanger, with a high-performance nickel alloy being used only where temperature and pressure dictate its use. Specifically, powder bed fusion (PBF) would be used to create the low-temperature portion of the recuperator in stainless steel 316L, then the high temperature region would be added directly to the low-temperature portion in Inconel 625 using directed energy deposition (DED). This methodology would have the additional benefit of being able to manufacture the heat exchanger headers at the same time as the core. In this project, a 1-D model of such a heat exchanger is devised which models the variability of both fluid and solid properties.
The design of the heat exchanger core is based on existing PCHE core designs. While optimizing the core design, a number of different channel shapes and fin configurations are considered. Arrays of airfoil fins appear to have comparable heat transfer performance with reduced pressure drop when compared to other core designs. A multi-objective optimization of a small-scale heat exchanger is then performed using the 1-D model in order to determine the dimensional parameters which simultaneously maximize the heat exchanger effectiveness and minimize its size. Two designs appear in the Pareto front resulting from this optimization. Analysis shows that the design with less heat transfer area achieves higher effectiveness by limiting axial conduction in the walls of the recuperator while also suffering much less pressure drop in both fluids.
The Effect of Pitch on Heat Transfer to an Immersed Heat Exchanger in a Solar Thermal Storage Tank With and Without a Baffle
Authors: Nicodemus Julia Haltiwanger , Smith Joshua , Holme Alexander , Johnson Sarah , Petitt Kyle 
Published: September 2022

Abstract
The effect of the pitch of a copper coil heat exchanger immersed in a hot water storage tank on heat transfer from the storage tank to the heat exchanger working fluid is investigated. The storage tank is initially quiescent and full of hot water. The heat exchanger located at the top of the tank has a coil diameter just under the tank diameter and has a pitch of 2, 3, 4, 6 or 12 times the heat exchanger diameter, D. The effect of the pitch is explored both with and without a cylindrical baffle, which creates an annular region with the tank wall that has a width of 1.5D and within which the heat exchanger is located. In experiments without the baffle, increasing the heat exchanger pitch improves the rate of heat transfer to the working fluid. The improved heat transfer is attributed to the increased thermal stratification generated by the larger pitches. In experiments with the baffle, the results for experiments with pitches of 2D, 3D, 4D and 6D are all very similar, with 3D slightly outperforming the others. Heat transfer to the heat exchanger with a 12D pitch was significantly lower than the others. In experiments both with and without the baffle, the larger pitches resulted in more variation in experimental results, despite strict standards for initial and operating conditions. As in prior work, the presence of the baffle resulted in significantly higher heat transfer rates compared to respective experiments without the baffle. For example, relative to their respective experiments without a baffle, the energy extracted from the tank after 30 min of discharge in the 2D, 3D, 4D, 6D, and 12D experiments is 18.3%, 18.8%, 13.9%, 11.9%, and 5.0% higher, respectively.
Net-Zero Energy Home Design Using Photovoltaic-Based Distributed Energy Generation and Multi-Functional Variable Refrigerant Flow Systems Integrated With Thermal Energy Storage
Authors: Kim Dongsu , Tran Kelly , Koh Jaeyoon , Cho Heejin 
Published: September 2022

Abstract
Net-zero energy homes (NZEHs) have been studied widely from different perspectives to provide realistic and practical solutions. Among various approaches to enable NZEH designs, energy-efficient heating, ventilation, and air-conditioning (HVAC) systems play a key role in providing thermal comfort and good air quality in a cost- and energy-efficient manner. This study proposes a NZEH design using photovoltaic (PV)-based distributed energy generation and multi-functional variable refrigerant flow (VRF) systems with electric and thermal energy storage systems. Simulation-based NZEH performance evaluation is conducted based on case studies under various US climate conditions. To develop a validated NZEH simulation model, the net-zero energy residential test facility (NZERTF) constructed by the US National Institute of Standards and Technology (NIST) is used for benchmarking the NZEH reference model. Changes in monthly energy consumption and on-site power generation before and after the VRF application are analyzed to capture the potential impact of the VRF system application for the NZEH design. This study shows that the alternative NZEH design with the proposed VRF and electric and thermal energy storage systems can achieve around 13% through 32% of cooling energy reductions under different US climate conditions. With the proposed VRF system, the savings potential of domestic hot water energy consumption is significant up to 90% reduction compared to the original NZEH before the proposed VRF and energy storage systems were considered.
Global Missile Proliferation: Challenges and Solutions
Authors: Bogdanov K. V. , Stefanovich D. V. 
Published: September 2022

Abstract
Developments in missile proliferation are analyzed, including the main drivers, trends, and actors. The increasing complexity of the global missile proliferation landscape is shown. They key areas of technological development are identified, as well as several types of missile proliferators, to substantiate the importance of missile proliferation in the context of international security. Existing and prospective mechanisms are discussed with respect to arms control, nonproliferation, and multilateral risk reduction measures. It is stressed that the existing mechanisms are aimed primarily at reducing the risks associated with creating delivery vehicles for weapons of mass destruction whereas the greatest importance is now attached to the potential use of conventionally armed missiles. It is proposed to concentrate efforts on “soft arms control” in order to lay a foundation for a gradual increase in controllability in the absence of real prospects for verifiable and intrusive multilateral measures.
Explaining Russia: The View from the Failed Future
Authors: Obichkina E. O. 
Published: September 2022

Abstract
Foreign publications by Russian historians specializing in country studies are a special genre of scientific research. They are designed to address pressing issues related to Russia that are in the focus of attention of foreign audiences. The complex of French publications by one of the best Russian specialists in French history and diplomat Yu.I. Rubinskii, written mostly from 1997 through the 2000s, is dedicated to the European future of Russia. The author employs a wide array of historical−political analysis methods to overcome prejudice and the stereotypical understanding of Russian foreign policy interests. He believes that the crisis in the trilateral relationship between Russia, Ukraine, and the West is rooted in clashing political and energy interests. The collapse of the Soviet Union is positioned as part of the global dissolution of colonial empires. Possible cooperation of Russia and the United States in Central Asia is considered in the logic of a “great game.” Rubinskii’s ideas are based on his understanding of the European perspective, which is rather close to the views of French scholars. Their core is the coexistence of the European Union (as opposed to the North Atlantic Alliance) and Russia in accordance with the pragmatic harmonization of economic and energy interests and the common security space.
Video analysis of Achilles tendon rupture in male professional football (soccer) players: injury mechanisms, patterns and biomechanics
Authors: Della Villa Francesco , Buckthorpe Matthew , Tosarelli Fillippo , Zago Matteo , Zaffagnini Stefano , Grassi Alberto 
Published: September 2022

BackgroundAchilles tendon rupture (ATR), while rare in football, is a severe career-threatening injury associated with long-layoff times. To date, no study has documented ATR’s mechanism in professional football players.AimTo describe the mechanisms, situational patterns and gross biomechanics (kinematics) of ATR injuries in professional male football players.MethodsEighty-six (n=86) consecutive ATR injuries in professional football players during official matches were identified. Sixty (70%) injury videos were identified for mechanism and situational pattern, with biomechanical analysis feasible in 42 cases. Three independent reviewers evaluated the injury videos. Distribution of ATR during the season, the match play and on the field were also reported.ResultsFifty (n=50, 83%) injuries were classified as non-contact and 10 (17%) as indirect contact. ATRs are injuries occurring during accelerations; three main situational patterns were identified: (1) forward acceleration from standing (n=25, 42%); (2) cross-over cutting (n=15, 25%) and (3) vertical jumping (n=11, 18%). Biomechanically, ATR injuries were consistent with a multiplanar loading at the injury frame consisting of a slightly flexed trunk (15.5°), extended hip (−19.5°), early flexed knee (22.5°) and end-range dorsiflexed (40°) ankle in the sagittal plane and foot pronation; 27 (45%) ATRs occurred in the first 30 min of effective match time.ConclusionsAll ATRs in professional football were either non-contact (83%) or indirect contact (17%) injuries. The most common situational patterns were forward acceleration from standing, cross-over cutting and vertical jumping. Biomechanics was consistent and probably triggered by a multiplanar, although predominantly sagittal, loading of the injured Achilles tendon.
Shorter versus longer corticosteroid duration and recurrent immune checkpoint inhibitor-associated AKI
Authors: Gupta Shruti , Garcia-Carro Clara , Prosek Jason M , Glezerman Ilya , Herrmann Sandra M , Garcia Pablo , Abudayyeh Ala , Lumlertgul Nuttha , Malik A Bilal , Loew Sebastian , Beckerman Pazit , Renaghan Amanda D , Carlos Christopher A , Rashidi Arash , Mithani Zain , Deshpande Priya , Rangarajan Sunil , Shah Chintan V , Seigneux Sophie De , Campedel Luca , Kitchlu Abhijat , Shin Daniel Sanghoon , Coppock Gaia , Ortiz-Melo David I , Sprangers Ben , Aggarwal Vikram , Benesova Karolina , Wanchoo Rimda , Murakami Naoka , Cortazar Frank B , Reynolds Kerry L , Sise Meghan E , Soler Maria Jose , Leaf David E 
Published: September 2022

BackgroundCorticosteroids are the mainstay of treatment for immune checkpoint inhibitor-associated acute kidney injury (ICPi-AKI), but the optimal duration of therapy has not been established. Prolonged use of corticosteroids can cause numerous adverse effects and may decrease progression-free survival among patients treated with ICPis. We sought to determine whether a shorter duration of corticosteroids was equally efficacious and safe as compared with a longer duration.MethodsWe used data from an international multicenter cohort study of patients diagnosed with ICPi-AKI from 29 centers across nine countries. We examined whether a shorter duration of corticosteroids (28 days or less) was associated with a higher rate of recurrent ICPi-AKI or death within 30 days following completion of corticosteroid treatment as compared with a longer duration (29–84 days).ResultsOf 165 patients treated with corticosteroids, 56 (34%) received a shorter duration of treatment and 109 (66%) received a longer duration. Patients in the shorter versus longer duration groups were similar with respect to baseline and ICPi-AKI characteristics. Five of 56 patients (8.9%) in the shorter duration group and 12 of 109 (11%) in the longer duration group developed recurrent ICPi-AKI or died (p=0.90). Nadir serum creatinine in the first 14, 28, and 90 days following completion of corticosteroid treatment was similar between groups (p=0.40, p=0.56, and p=0.89, respectively).ConclusionA shorter duration of corticosteroids (28 days or less) may be safe for patients with ICPi-AKI. However, the findings may be susceptible to unmeasured confounding and further research from randomized clinical trials is needed.