bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS TINGKAT KESEHATAN BANK DENGAN METODE RGEC PADA PT BANK CENTRAL ASIA, TBK (BCA) PERIODE 2017-2021
Authors: Rini Dwiastutiningsih  , Dadi Kuswandi  , Titah Ayu  
Published: November 2022

Lembaga perbankan merupakan salah satu aktivitas perekonomian yang memiliki peranan penting didalam dunia keuangan. Salah satu peranan bank adalah menghimpun dana dari masyarakat dan menyalurkan kembali dana kepada masyarakat. Penilaian Tingkat Kesehatan Bank dimaksudkan agar perbankan dapat menilai keberhasilan sistem perbankan dalam perekonomian Indonesia. Adanya krisis global dan menurunnya simpanan masyarakat membuat perbankan harus menjaga dana yang dibutuhkan untuk menjaga likuiditas perbankan melalui tingkat suku bunga yang tinggi. Tujuan dilakukan penelitian ini untuk mengetahui tingkat kesehatan PT Bank Central Asia (BCA), Tbk dengan menggunakan metode RGEC (Risk Profile, Good Corporate Governance, Earnings, and Capital) pada periode tahun 2017-2021. Penelitian ini menggunakan metode kuantitatif dengan jenis penelitian adalah penelitian deskriptif melalui data sekunder. Hasil dari penelitian dari analisis tingkat kesehatan bank dengan metode RGEC pada PT Bank Central Asia (BCA), Tbk periode 2017-2021 dalam kondisi “Sangat Sehat”. Dilihat dari faktor Risk Profile yang dinilai dengan rasio NPL Gross mendapatkan predikat "Sangat Sehat" dan rasio LDR PT Bank Central Asia (BCA), Tbk mendapatkan predikat "Sehat". Pada faktor Good Corporate Governance (GCG) pada PT Bank Central Asia (BCA), Tbk mampu menerapkan penilaian GCG dengan "Sangat Baik" dan manajemen sudah menerapkan self-assessment. Pada faktor Earnings yang dinilai dengan rasio Return On Assets (ROA) dan rasio Net Interest Margin (NIM) PT Bank Central Asia (BCA), Tbk mendapatkan predikat "Sangat Sehat". Pada faktor Capital yang dinilai dengan rasio Capital Adequacy Ratio (CAR) mendapat predikat "Sangat Sehat”.
Analisis Perancangan Antena Yagi Menggunakan Teknik Fraktal Frekuensi UHF
Authors: Bryan Wakita  
Published: November 2022

Hal pertama yang perlu diperhatikan dalam merancang antenna adalah frekuensi yang digunakan. Frekuensi berpengaruh terhadap ukuran antenna. Semakin kecil antenna maka dimensi ukuran antenna semakin besar, begitu pula sebaliknya. Frekuensi yang digunakan pada penelitian ini adalah frekuensi UHF (600 MHz). antenna yang dirancang berjenis antenna yagi yang berdasarkaan frekuensi tersebut maka ukuran antenna terbilang besar. Untuk dapat mereduksi ukuran fisik antena dengan mempertahankan atau meningkatkan performansi antena tersebut, salah satu teknik yang dapat diterapkan adalah teknik fraktal Kurva Koch. Dari hasil simulasi antenai, diperoleh parameter karakteristik antena yaitu gain sebesar 12.9 dBi, VSWR 1.4, dan pola radiasi unidireksional. Setelah diterapkan teknik fraktal Kurva Koch iterasi 1 diperoleh kenaikan gain sebesar 7.3%, VSWR 1.18, pola radiasi unidireksional dan penurunan panjang fisik linear antena sebesar 7.4%.
Monitoring and baseline of glyphosate-resistant sourgrass in the main soybean growing regions of Brazil
Authors: Gonçalves Netto Acácio , Carvalho Saul Jorge Pinto de , Nicolai Marcelo , Lopez Ovejero Ramiro Fernando , Presoto Jéssica Cursino , Andrade Jeisiane de Fátima , Resende Laís Sousa 
Published: November 2022

Frequent application of glyphosate for consecutive years has enhanced the selection pressure on sourgrass (Digitaria insularis) populations, which resulted in the development of glyphosate-resistant biotypes. Therefore, this work was developed with the objective of monitoring sourgrass resistance to glyphosate, develop a baseline of sourgrass susceptibility to this molecule and, consequently, identify the discriminatory dose between resistant and susceptible populations. This work was divided into three steps. The first step consisted of identifying and sorting sourgrass resistant and susceptible biotypes among 30 samples. In the second step, glyphosate baseline was elaborated considering exclusively the glyphosate-susceptible biotypes, which allowed the definition of a discriminatory dose. At the end, the third step, monitoring of glyphosate-resistant biotypes was achieved, considering five growing seasons (2016 – 2020) and 809 samples of sourgrass populations, collected throughout 12 states of Brazil. Glyphosate baseline was elaborated to sourgrass and ideal discriminatory rate was identified as 960 g ha-1. Glyphosate-resistant populations of sourgrass were found in all soybean growing regions sampled. Among 809 populations, 25.96% were considered resistant to glyphosate. The states with the highest frequency of glyphosate-resistant populations were Rio Grande do Sul, Mato Grosso do Sul, Bahia, Mato Grosso and Paraná.
Sålding av løsmasser fra Kjellerhaugen på Seivåg
Authors: Blom Jon Gunnar 
Published: November 2022

Prosjektet omfattet sålding av masser som lå over en forstyrret grav på Kjellerhaugen (se Henriksen 2022), samt sålding av masser fra grøfteoppkast i forbindelse med graving av ny vannlinjetrasé til våningshuset.
Det ble funnet flere beinfragmenter og gjenstander, men ingen av beinene stammet fra menneske og gjenstandene var moderne.
Factors Influencing Changing Boundaries and/or Routes of Fulani Herders in the North Eastern Corridors of Ghana: A Count Model Approach
Authors: Yenibehit Nanii , Amikuzuno Joseph , Abubakari Abdulai 
Published: November 2022

This study was designed to examine the factors influencing the movement or changing of herding routes among herders in the North – Eastern corridor of the Northern and Northeast Regions of Ghana. The study followed a cross-sectional descriptive survey research design and adopted the Poison and Negative Binomial regression Models. A total of 210 Fulani herders and seven community/opinion leaders from seven communities across four (4) districts were randomly selected for this study. Duration of a herder’s stay in a community (P≤.01), being given a range of land for kraaling or grazing (P≤.01), having access to education for children (P≤0.1), losing cattle before (P≤.01) and ever being harmed or witnessing same due to conflict (P≤.01) are important factors that prevent or reduce the number of times a herder changes location or route. On the other hand, factors including hired herding (P≤.01), years of education of a herder (P≤.05) and restriction or lack of grazing land for cattle (P≤.1) are some of the most compelling factors that lead to changes in location or herding routes of Fulani herders. Fulani herders should be registered and integrated into the various communities whilst encouraging them to educate their children and have permanent living status.
The Nutcracker Syndrome: Rare Cause of Pediatric Abdominal Pain
Authors: Elmahi J. , Amhager S. , Kriouel Y. 
Published: November 2022

Nutcracker syndrome results from compression of the left renal vein (LRV), usually in the fork formed by the abdominal aorta and the superior mesenteric artery (SMA), leading to stenosis of the aorto-mesenteric part of the left renal vein and dilation of its distal part. We report the case of a 10-year-old child, with no family history of renal disease, diabetes or hematuria. He was admitted to our clinic for paroxysmal abdominal pain in the epigastric area that was not improved by the usual analgesics, associated with vomiting without transit disorders or hematuria, and had been evolving for 10 days prior to his admission. The clinical examination was normal, the normal biological check-up, the abdominal CT scan was in favor of the Nutcracker syndrome. The treatment was symptomatic with a good evolution.
Nutcracker syndrome is a rare entity, to be evoked in the diagnostic range of rare etiologies of unexplained abdominal pain.
Geo-spatial Analysis of the Nexus between Population Growth, Environmental Transformation and Local People’s Livelihoods in Coastal Areas: The Case Study of Kigamboni Municipality, Tanzania
Authors: Malekela Asnath Alberto 
Published: November 2022

The world is facing an unprecedented population increase in coastal areas. This situation is mainly the result of human migration. The population increase has multiplier effects on the environment and development. In Kigamboni Municipality, land-use changes have been witnessed and new expansions, including agricultural, commercial, industrial and urban-related expansions, happen every day. Thus, this study investigates the impact of population growth on the environment and the local people’s livelihoods in Kigamboni. Land-use/land-cover (LULC) changes were quantified using satellite images. In addition, a total of 156 respondents were randomly selected from four sub-wards in the municipality. Primary data were collected using a structured questionnaire, in-depth interviews, observations and focus group discussions (FGDs). Remote sensing techniques were used to map the spatial and temporal variation of the area between 1995 and 2021 by using a Supervised Classification method in Random Forest Classifier model in R software to generate land-cover types. Seven major LULC categories were identified. The results show that the area under cultivation and the built-up area increased by 40% and 4%, respectively, and that bushlands, forests and grasslands had a declining trend of 34%, 6% and 13%, respectively. The population increase has both positive and negative effects on the local people’s livelihoods, including access to social services, improvement of infrastructure, the availability of markets, the increase in waste, pollution and the increase of the cost of land. The study recommends the formulation of appropriate policies on land-use planning in relation to population dynamics.
Designing and Manufacturing a Single-Phase Transformer and Analyzing Its Performance
Authors: Arafat Eyasir , Oyon Md. Shihab Sharar , Kabbyo Md. Habib A Hasan , Khan Khan Mohammad , Shuvo , Md. Shahriar Hasan , Sarker Arnab , Haque Md. Rokibul , Islam Rakibul , Bhuyan Muhibul Haque 
Published: November 2022

Aims: This work aims to design a single-phase transformer for analyzing its performance based on some requirements.
Study Design: At first, requirements are set, then the design was completed using AutoCAD, after that the designed machine was simulated in MATLAB Simulink, manufactured in real-time in the laboratory, tested experimentally, and then the equivalent circuit parameters were computed from the experimental data.
Place and Duration of Study: The design, manufacturing, simulation, and performance testing were conducted in the electrical machine 1 laboratory of American International University-Bangladesh (AIUB). It took around four months to complete the whole task.
Methodology: This work is a bit expensive and complicated process for students without any funds. So, a group was formed with eight students. The tasks were to design, simulate, implement, and test a single-phase transformer that would step down 220 V (ac) to 110 V (ac) having a 440 VA capacity, and core loss should not exceed 5 W.
Results: MATLAB Simulink was used to simulate the designed transformer to get the primary and secondary winding voltage and current wave shapes that were confirmed by the experimental results. Open and short circuit tests indicate that loss is only between 5 W and 8 W respectively. The total design cost is only BDTK1, 270.
Conclusion: The results satisfied the design and performance parameter requirements and the designed transformer worked very well. The design cost was also kept minimum.
Association of Socioeconomic, Demographic, and Health Care Access Disparities With Severe Visual Impairment in the US
Authors: Besagar Sonya , Yonekawa Yoshihiro , Sridhar Jayanth , Finn Avni , Padovani-Claudio Dolly Ann , Sternberg Paul , Patel Shriji 
Published: November 2022

ImportanceApproximately 13% of US adults are affected by visual disability, with disproportionately higher rates in groups impacted by certain social determinants of health (SDOH).ObjectiveTo evaluate SDOH associated with severe visual impairment (SVI) to ultimately guide targeted interventions to improve ophthalmic health.Design, Setting, and ParticipantsThis quality improvement study used cross-sectional data from a telephone survey from the Behavioral Risk Factor Surveillance System (BRFSS) that was conducted in the US from January 2019 to December 2020. Participants were noninstitutionalized adult civilians who were randomly selected and interviewed and self-identified as “blind or having serious difficulty seeing, even while wearing glasses.”ExposuresDemographic and health care access factors.Main Outcomes and MeasuresThe main outcome was risk of SVI associated with various factors as measured by odds ratios (ORs) and 95% CIs. Descriptive and logistic regression analyses were performed using the Web Enabled Analysis Tool in the BRFFS.ResultsDuring the study period, 820 226 people (53.07% female) participated in the BRFSS survey, of whom 42 412 (5.17%) self-identified as “blind or having serious difficulty seeing, even while wearing glasses.” Compared with White, non-Hispanic individuals, risk of SVI was increased among American Indian/Alaska Native (OR, 1.63; 95% CI, 1.38-1.91), Black/African American (OR, 1.50; 95% CI, 1.39-1.62), Hispanic (OR, 1.65; 95% CI, 1.53-1.79), and multiracial (OR, 1.33; 95% CI, 1.15-1.53) individuals. Lower annual household income and educational level (eg, not completing high school) were associated with greater risk of SVI. Individuals who were out of work for 1 year or longer (OR, 1.78; 95% CI, 1.54-2.07) or who reported being unable to work (OR, 2.90; 95% CI, 2.66-3.16) had higher odds of SVI compared with the other variables studied. Mental health diagnoses and 14 or more days per month with poor mental health were associated with increased risk of SVI (OR, 1.87; 95% CI, 1.73-2.02). Health care access factors associated with increased visual impairment risk included lack of health care coverage and inability to afford to see a physician.Conclusions and RelevanceIn this study, various SDOH were associated with SVI, including self-identification as being from a racial or ethnic minority group; low socioeconomic status and educational level; long-term unemployment and inability to work; divorced, separated, or widowed marital status; poor mental health; and lack of health care coverage. These disparities in care and barriers to health care access should guide targeted interventions.
Monkeypox Virus and Ophthalmology—A Primer on the 2022 Monkeypox Outbreak and Monkeypox-Related Ophthalmic Disease
Authors: Kaufman Aaron R. , Chodosh James , Pineda Roberto 
Published: November 2022

ImportanceAn ongoing global monkeypox virus outbreak in 2022 includes the US and other nonendemic countries. Monkeypox ophthalmic manifestations may present to the ophthalmologist, or the ophthalmologist may be involved in comanagement. This narrative review creates a primer for the ophthalmologist of clinically relevant information regarding monkeypox, its ophthalmic manifestations, and the 2022 outbreak.ObservationsMonkeypox virus is an Orthopoxvirus (genus includes variola [smallpox] and vaccinia [smallpox vaccine]). The 2022 outbreak is of clade II (historically named West African clade), specifically subclade IIb. In addition to historic transmission patterns (skin lesions, bodily fluids, respiratory droplets), sexual transmission has also been theorized in the current outbreak due to disproportionate occurrence in men who have sex with men. Monkeypox causes a characteristic skin eruption and mucosal lesions and may cause ophthalmic disease. Monkeypox-related ophthalmic disease (MPXROD) includes a spectrum of ocular pathologies including eyelid/periorbital skin lesions, blepharoconjunctivitis, and keratitis). Smallpox vaccination may reduce MPXROD occurrence. MPXROD seems to be rarer in the 2022 outbreaks than in historical outbreaks. MPXROD may result in corneal scarring and blindness. Historical management strategies for MPXROD include lubrication and prevention/management of bacterial superinfection in monkeypox keratitis. Case reports and in vitro data for trifluridine suggest a possible role in MPXROD. Tecovirimat, cidofovoir, brincidofovir and vaccinia immune globulin intravenous may be used for systemic infection. There is a theoretical risk for monkeypox transmission by corneal transplantation, and the Eye Bank Association of America has provided guidance. Smallpox vaccines (JYNNEOS [Bavarian Nordic] and ACAM2000 [Emergent Product Development Gaithersburg Inc]) provide immunity against monkeypox.Conclusions and RelevanceThe ophthalmologist may play an important role in the diagnosis and management of monkeypox. MPXROD may be associated with severe ocular and visual morbidity. As the current outbreak evolves, up-to-date guidance from public health organizations and professional societies are critical.
The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile
Authors: Lee Michelle M. , McDowell Graeme S. V. , De Vivo Darryl C. , Friedman Daniel , Berkovic Samuel F. , Spanou Maria , Dinopoulos Argirios , Grand Katheryn , Sanchez‐Lara Pedro A. , Allen‐Sharpley Michelle , Warman‐Chardon Jodi , Solyom Alexander , Levade Thierry , Schuchman Edward H. , Bennett Steffany A. L. , Dyment David A. , Pearson Toni S. 
Published: November 2022

AbstractObjectiveThe objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.MethodsClinical features of 6 patients with SMA‐PME were assessed by retrospective chart review, and a literature review of 24 previously published cases was performed. Leukocyte enzyme activity of acid ceramidase was assessed with a fluorescence‐based assay. Skin fibroblast ceramide content and was assessed by high performance liquid chromatography, electrospray ionization tandem mass spectroscopy. Enzyme replacement was assessed using recombinant human acid ceramidase (rhAC) in vitro.ResultsThe six new patients showed the hallmark features of SMA‐PME, with variable initial symptom and age of onset. Five of six patients carried at least one of the recurrent SMA‐PME variants observed in two specific codons of ASAH1. A review of 30 total cases revealed that patients who were homozygous for the most common c.125C > T variant presented in the first decade of life with limb‐girdle weakness as the initial symptom. Sensorineural hearing loss was associated with the c.456A > C variant. Leukocyte acid ceramidase activity varied from 4.1%–13.1% of controls. Ceramide species in fibroblasts were detected and total cellular ceramide content was elevated by 2 to 9‐fold compared to controls. Treatment with rhAC normalized ceramide profiles in cultured fibroblasts to control levels within 48 h.InterpretationThis study details the genotype–phenotype correlations observed in SMA‐PME and shows the impact of rhAC to correct the abnormal cellular ceramide profile in cells.
Engineering Vascular Self‐Assembly by Controlled 3D‐Printed Cell Placement
Authors: Orellano Isabel , Thomas Alexander , Herrera Aaron , Brauer Erik , Wulsten Dag , Petersen Ansgar , Kloke Lutz , Duda Georg N. 
Published: November 2022

AbstractNutrient supply via a functional vasculature is essential during regenerative processes, tissue growth, and homeostasis. 3D bioprinting offers the opportunity to engineer vascularized constructs by combining cells and biocompatible materials in specifically designed fashions. However, the complexity of microvascular dynamic networks can hardly be recapitulated yet, even by sophisticated 3D manufacturing. Ideally, the natural organizational competences of endothelial cells will be harnessed such that engineered vascular networks self‐assemble to form complex, controllable microvascular patterns. Here, a bioengineering approach is presented to control microvascular structure formation and to steer cellular self‐assembly of endothelial and supporting cells within a multi‐material stereolithographic 3D bioprinting concept. Bioengineered vascularized constructs are generated by controlled cell deposition in an enzymatically degradable or a non‐degradable material. In vitro, the microvascular structures are regulated in distribution, network orientation, vessel length and branching behavior and developed lumen, signs of vascular stabilization and an interconnected vascular network including anastomosis. This novel biofabrication approach demonstrates the capability to control microvascular network formation by using cellular and spatial cues allowing the generation of distinctly yet precisely vascularized constructs. Such novel approach of controlled microvascular formation may play a fundamental role in the development of vascularized implants or in vitro screening models.
Lipid Nanoparticle Delivery of Chemically Modified NGFR100W mRNA Alleviates Peripheral Neuropathy
Authors: Yu Xiang , Yang Zheng , Zhang Yu , Xia Jia , Zhang Jiahui , Han Qi , Yu Hang , Wu Chengbiao , Xu Yingjie , Xu Wei , Yang Wen 
Published: November 2022

AbstractMessenger RNA (mRNA) carries genetic instructions to the cell machinery for the transient production of antigens or therapeutic proteins and shows enormous potential in vaccine development, cancer immunotherapy, protein replacement therapy, and genome engineering. Here, the synthesis of chemically modified nerve growth factor mutant (NGFR100W) mRNA through in vitro transcription is described. After the replacement of the original signal peptide sequence with the Ig Kappa leader sequence, codon‐optimized NGFR100W mRNA yielded high secretion of mature NGFR100W, which promotes axon growth in PC12 cells. Using lipid nanoparticle (LNP)‐delivery of N1‐methylpseudouridine‐modified mRNA in mice, NGFR100W‐mRNA‐LNPs result in the successful expression of NGFR100W protein, which significantly reduces nociceptive activity compared to that of NGFWT. This indicates that NGFR100W derived from exogenous mRNA elicited “painless” neuroprotective activity. Additionally, the therapeutic value of NGFR100W mRNA is established in a paclitaxel‐induced peripheral neuropathy model by demonstrating the rapid recovery of intraepidermal nerve fibers. The results show that in vitro‐transcribed mRNA has significant flexibility in sequence design and fast in vivo functional validation of target proteins. Furthermore, the results highlight the therapeutic potential of mRNA as a supplement to beneficial proteins for preventing or reversing some chronic medical conditions, such as peripheral neuropathy.
Precise Functionalization of a Multiple‐Resonance Framework: Constructing Narrowband Organic Electroluminescent Materials with External Quantum Efficiency over 40%
Authors: Wang Qingyang , Xu Yincai , Yang Tong , Xue Jianan , Wang Yue 
Published: November 2022

AbstractIt is of important strategic significance to develop high‐efficiency narrowband organic electroluminescent materials that can be employed to fabricate ultrahigh‐definition displays with wide color gamut. This topic implies a great challenge to molecular design and synthesis, especially for the development of universality, diversity, scalability, and robustness of molecular architectonics. In this work, a synthetic methodology is demonstrated for functionalizing brominated BN‐containing multiple‐resonance (MR) frameworks with multifarious functional groups, such as donors, acceptors, and moieties without obvious push–pull electron properties. The m‐DPAcP–BNCz‐based organic light‐emitting diode (OLED) exhibits green emission with a full‐width at half‐maximum (FWHM) of 28 nm and a maximum external quantum efficiency (EQE) of 40.6%. The outstanding performance of m‐DPAcP–BNCz is attributed to the perfect integration of the inherent advantages of the MR framework and the donor–acceptor configuration, which can not only achieve bathochromic shift and narrowband emission, but also obtain high photoluminescence (PL) quantum yield (ΦPL) and horizontal emitting dipole orientation ratio (Θ//). This straightforward and efficient approach provides insightful guidance for the construction and enrichment of more high‐efficiency narrowband emitters.