bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pembuatan Hand Sanitizer Dan Sabun Cuci Tangan Sebagai Upaya Pencegahan Penularan Covid-19 di Puskemas Penawangan Grobogan
Authors: Kurniasari Laeli , Maharani Farikha , Syafa’at Imam , Dzulfikar Muhammad , Hartati Indah 
Published: November 2022

Penggunaan hand sanitizer serta penerapan pola hidup bersih dan sehat merupakan bagian dari upaya pencegahan dan pemutusan mata rantai penyebaran COVID-19. Salah satu intansi yang memiliki tugas untuk mensosialisasikan dan menggalakkan upaya tersebut adalah Puskesmas. Personil di Puskesmas memerlukan wawasan mengenai komposisi dan cara pembuatan hand sanitizer dan sabun cuci tangan. Kegiatan ini bertujuan memberikan pelatihan proses produksi hand sanitizer dan sabun cuci tangan kepada personil Puskesmas Penawangan Grobogan. Kegiatan dilakukan melalui tahapan uji coba proses produksi di kampus, dilanjutkan dengan proses pelatihan di puskesmas serta diakhiri dengan penyerahan produk hand sanitizer dan sabun cuci tangan kepada Puskesmas Penawangan Grobogan. Uji coba proses produksi hand sanitizer dan sabun cuci dilakukan dengan menggunakan komposisi sebagaimana tercantum dalam ketentuan WHO. Proses pelatihan telah berhasil memberikan wawasan bagi personil di Puskesmas mengenai cara produksi hand sanitizer dan sabun cuci tangan. Produk yang dihasilkan telah diserahkan kepada Puskesmas Penawangan Grobogan guna mendukung upaya pencegahan dan pemutusan mata rantai penyebaran COVID-19. Kata Kunci: Covid-19, Hand Sanitizer, Sabun cuci tangan.Abstract. The use of hand sanitizer as well as the healty lifestyle are parts of Covid-19 prevention and transmission chain breaking. Public health center (Puskesmas) is one of health institution having responsibility in informing and promoting of those efforts. Public health centers need to be supported by the continous supply of hand sanitizers and handsoaps while the health workers should be sthrengthened by providing outlook on the chemical compostion and the procedure of the hand sanitized and handsoap production process. This paper reports the strenghtening efforts of public health center of Penawangan Grobogan by provide training to the health workers on the chemical compostion and the procedure of the hand sanitized and handsoap production process as well as handover of the hand sanitizers and handsoaps to the public health center of Penawangan Grobogan. This community service was initially performed by producing hand sanitizers and handsoaps based on product compositions suggested by WHO. The service was followed by the training to the health workers on the chemical compostion and the procedure of the hand sanitized and handsoap production process. The hand sanitizers and handsoaps were handed over to the public health center of Penawangan Grobogan. Keywords: Covid-19, Hand Sanitizer, handsoap.
EXPLORING STUDENTS’ PERCEPTION ON THE USE OF MY BEST MOODLE IN LEARNING ENGLISH DURING COVID-19 OUTBREAK
Authors: Amelia Mike , Handayani Fitri 
Published: November 2022

This article describes a design research project at Bina Sarana Informatika University to construct an e-learning web-based moddle. During the Covid-19 outbreak, the study used My Best Moddle of instructional growth in learning process. This article focuses on how students' perceptions of the moodle's implementation were evaluated. The methode of research is descriptive quantitiave. The study included a number of fourth-semester students of Bina Sarana Informatika University as a population and 30 students were selected by using random sampling technique. A questionnaire and an interview were used to gather information. The students thought the My Best e-learning moodle was helpful in enhancing their motivation to learn English as well as their relationships with each other and the lecturer during online learning. Students also agreed that the My Best e-learning module was simple to utilize. It can be stated that the students’ perception on the use of My Best in learning English have positive respond. The students' issues were a drop in seriousness and degree of concentration during online studying. It is influenced by the learning environment. The internet connection is unstable, and devices like smartphones and laptops are not equipped to facilitate accessing e-learning. Materials were also challenging for the students to understand, and they had trouble completing their own tasks as well as group projects that required internet collaboration. The final issue was how easily stressed out students became while engaging in online learning. Based on the findings, it can be said that while students benefited from e-learning, there are some issues with its abrupt adoption and lack of planning. So that the objectives and standards of education can be achieved.
Gamification of the overexploitation of natural resources. An operational game based on System Dynamics
Authors: Bardi Ugo , Perissi Ilaria 
Published: November 2022

Overexploitation is the phenomenon that occurs when an economic resource is exploited at a rate faster than it can be regenerated by natural processes. It affects both renewable and non-renewable resources. Overexploitation, and the related effect of “overshoot,” may lead to the complete destruction of the resource being exploited and the collapse of the economic system exploiting it. Nevertheless, overexploitation is common in the economy, although its mechanisms and consequences are often unknown to the public and to decision makers. The present paper aims at providing a tool to disseminate the concept of overexploitation by simulating it using the technique of “gamification.” We created a simple boardgame based on a system dynamics model that maintains the basic elements that generate overexploitation. The game is called the “Moby Dick Game” and it is inspired by the whaling cycle of the 19th century. Other versions of the game can be used to simulate, for instance, oil extraction. The game was tested on several groups of students and interested people with different backgrounds. The players usually reported to have learned for the first time the mechanisms that lead to overexploitation and collapse.
Low Donor Site Morbidity Supports the Use of Infraumbilical Flaps for Head and Neck Reconstruction: A Retrospective Cohort Study
Authors: Bettini Giordana , Saia Giorgia , Franco Piero , Valsecchi Stefano , Tognin Laura , Alexandre Enrico , Bedogni Alberto 
Published: November 2022

Background: Currently, the standard design of the skin component of abdominal soft-tissue flaps recommended for head and neck reconstruction encompasses the upper and lower periumbilical region to include the maximum number of myocutaneous perforators. Yet, this flap design precludes the harvest of bilateral flaps and the use of the contralateral area in case of flap failure. Aim: We aimed at proving the long-term safety of infraumbilical abdominal free flaps in terms of abdominal wall integrity.

Methods: Consecutive subjects who underwent reconstruction of composite cervico-facial defects with infraumbilical free flaps between 2008 - 2020 were enrolled. After surgery, patients were followed up at three-month intervals to evaluate the incidence of any complications at the donor site.

Results: 25 patients underwent reconstruction with free flaps from the lower abdomen. A total of 35 abdominal flaps were performed; ten patients underwent bilateral flap harvest. Marginal abdominal skin necrosis occurred in 3 patients. Abdominal bulge occurred in one case; neither hernia nor abdominal wall weakness was encountered at a median follow-up of 12 months. Conclusions: The infraumbilical region is a safe donor area of free flaps for head and neck reconstruction that preserves abdominal wall firmness and provides a satisfactory cosmetic result at the donor site.
ANALISIS KINERJA KEUANGAN MENGGUNAKAN METODE ECONOMIC VALUE ADDED (EVA) DAN FINANCIAL VALUE ADDED (FVA) (STUDI KASUS PADA RUMAH SAKIT MITRA KELUARGA TAHUN 2017-2021)
Authors: Oktavia Sri Nur , Hartati Nani 
Published: November 2022

Perusahaan yang bergerak dalam bidang kesehatan salah satu yaitu Rumah Sakit Mitra Keluarga. Rumah sakit yang bergerak pada bidang kesehatan serta beroperasi hampir di seluruh Indonesia dan sebagai salah satu rumah sakit terbesar di Indonesia. Di masa pandemi seperti sekarang ini rumah sakit harus mampu bersaing dengan rumah sakit lainnya, seperti dengan cara rumah sakit harus bisa meningkatkan kinerjanya, kinerja dalam melayani pasien atau bahkan kinerja keuangannya. Kondisi keuangan rumah sakit yang tidak stabil tentunya sangat berdampak besar terhadap kinerja keuanga rumah sakit. Sehingga perlu dilakukan pengukuran kinerja untuk mengetahui kekuatan dan kelemahan rumah sakit. Kinerja keuangan suatu perusahaan dapat dinilai dengan menggunakan beberapa alat analisis keuangan, salah satunya pengukuran kinerja berdasarkan nilai (Value Based) yaitu Economic Value Added (EVA) dan Financial Value Added (FVA). Tujuan dari penelitian ini adalah untuk mengetahui gambaran kinerja keuangan pada Rumah Sakit Mitra Keluarga yang diukur menggunakan metode Economic Value Added (EVA) dan Financial Value Added (FVA) pada tahun 2017 sampai dengan tahun 2021. Metode penelitian yang digunakan adalah metode penelitian kuantitatif, sumber data yang diperoleh adalah data sekunder. Metode pengumpulan data menggunakan metode dokumentasi dan metode studi kepustakan. Hasil penelitian ini menunjukkan bahwa kinerja keuangan Rumah Sakit Mitra Keluarga tahun 2017 sampai 2021 menggunakan metode Economic Value Added (EVA), Rumah Sakit tidak mampu menciptakan nilai tambah ekonomi yang mengarah pada kinerja yang buruk (EVA<0). Tetapi kinerja keuangan Rumah Sakit yang diukur menggunakan Financial Value Added (FVA) menghasilkan kinerja yang baik karena Rumah Sakit sudah mampu menghasilkan nilai tambah finansial (FVA>0).
PENERAPAN METODE SIMPLE ADDITIVE WEIGHTING UNTUK PENILAIAN DAN EVALUASI KEHADIRAN KARYAWAN PADA PRESENSI BERBASIS QR CODE (STUDI KASUS RITMALL)
Authors: Pertiwi Noviarsih Indah , Suharsono Teguh Nurhadi , Pakpahan Andy Victor 
Published: November 2022

RitMall One Stop IT Solution merupakan suatu perusahaan yang bergerak di bidang jasa pembuatan aplikasi website. Terdapat kendala yang dihadapi pada presensi karyawan di perusahaan ini yaitu dalam presensi karyawan masih dilakukan secara tertulis belum menggunakan sistem terkomputerisasi. Presensi merupakan sebuah pengambilan data guna mengetahui jumlah kehadiran karyawan pada suatu Instansi Pemerintah / Perusahaan. Telah dilakukan analisis pada perusahaan RitMall, dimana kendala yang sering terjadi diantaranya mengisi presensi masih menggunakan kertas dengan cara tanda tangan pada setiap karyawan. Dan terjadi kelemahan dalam kehadiran karyawan untuk mendata kehadiran perbulan akibat laporan presensi yang kurang tepat dan akurat serta dalam penilaian kehadiran sulit untuk ditentukan sebagai bahan evaluasi. Oleh karena itu, dirancanglah sebuah sistem presensi qr code karyawan berbasis website yang memberikan kemudahan dalam presensi dan mempermudah untuk mengelola data karyawan serta dalam penilaian kehadiran karyawan sebagai evalusi maka menerapkan metode Simple Additive Weighting (SAW) untuk mempermudah dalam penilaian karena metode SAW melakukan perhitungan normalisasi dan perangkingan untuk menentukan karyawan mana yang terbaik dalam kehadirannya.
PERANCANGAN SISTEM INFORMASI PERSEDIAAN BARANG MENGGUNAKAN METHODOLOGI SCRUM (STUDI KASUS: MINI MARKET IBU WATI)
Authors: Aspahani Syifa , Purnama Asep Muhammad Indra 
Published: November 2022

Peran sistem informasi sangat diperlukan di era globalisasi saat ini untuk mendukung berbagai jenis aktivitas. Diantaranya membagikan informasi yang efektif dan akurat, mengelola data perusahaan dalam jumlah tidak sedikit dengan baik, serta membantu perusahaan membuat keputusan yang tepat dalam mengembangkan strategi dan kebijakan perusahaan. Minimarket sayuran merupakan UMKM yang bergerak di bidang kebutuhan pokok yang tepatnya berlokasi di Jalan Cikutra, Pasar Cikutra. Saat ini aktivitas pengelolaan data Minimarket Sayuran masih dilakukan secara manual. Setiap aktivitas keluar dan masuk barang hanya di catat sesuai dengan persediaan barang dagangan yang tersisa, atau terkadang hanya menggunakan kwitansi sebagai bukti barang keluar dan masuk. Pada jenis kegiatan persediaan ini, terdapat potensi keterlambatan pelaporan persediaan dan kesalahan pencatatan mutasi persediaan karena banyaknya jenis persediaan barang yang berbeda-beda. Dengan adanya sistem ini, dimulai dari proses pendataan barang keluar masuk, hingga pelaporan menjadi terkomputerisasi. Dalam penelitian ini menggunakan methodologi scrum.
Optimalisasi Perencanaan Tambang Berdasarkan Pemilihan Kebutuhan Alat Berat Untuk Mencapai Target Produksi di Tambang Besar (TB 2.2) Tempilang Front 1 Kec. Tempilang Mitra PT Timah (Persero) Tbk
Authors: Supriyadi Supriyadi , Mardiah Mardiah , Akuan Abrianto 
Published: November 2022

Mining activities in TB 2.2 TempilangSite was conducted by Bahtera Sarindo Utama as a partner of PT Timah (Persero) Tbk.The method and technology used in mining site was Mechanical Mine as an alternative of conventional open pit mining which had been applied to overcome a great lack of hydraulic mining. There were several problems occurred in tin mining activities of TB 2.2 Tempilang included less of cycle time of gravel pump per day due to several problems that appeared in mine site such as gravel pump were often broken, Front Work landslides, so the production activity was inefficient. Mine planning of Mining mechanical methods plan Mechanics in TB 2.2 TempilangSite had production target of 320 m3 / h or 5,760 m3 / day. Therefore it was necessary to optimize the mining design to make it more efficient. The study included the election needs of load haulage equipment and conveyance based fleet to achieve production targets.Based on the results obtained, the need of equipment in hydraulic mine method for IDH work Front 1 to achieve production target was4 units of hydraulic pump, 4 units of gravel pump, 3 units of Excavators and 4 units of Articular Dump Truck with the total production of 5,976 m3 / day, and if using mechanical mine methodthe needs of load haulage equipment and conveyance for IDH removal was 1 fleet, 2 units of CAT 320D2 Excavator and 6 units of CAT 740B ADT with a total production of 6588.00 m3 / day with the production rate at 9.20 % greater than hydraulic mine and fleet 2 such us 1 unit of 345D CAT Excavator and 6 units of CAT 740B ADT 6 with the total production of 6468.12 m3/ day with the production rate at 7.60% greater than hydraulic mine.Based on the results obtained, mine lifetime of TB 2.2 TempilanFront 1 was 6,13 years using hydraulic mine method, 5,57 years for Mechanical mine of fleet 1 and 5.67 years for fleet 2. From these results suggested, that would better to use mechanical mine method in the removal of IDH in TB 2.2 Tempilang. With the availability of load haulage equipments and conveyance would counduct with fleet 1.
Analisa Kestabilan Lereng Menggunakan Metode Fellenius Secara Manual dan Software Slide Rocscience 6.0 (Studi Kasus : TB 1.42 Pemali PT Timah (Persero) Tbk
Authors: Tiambunan Damos , Irvani Irvani , Fahraini Ferra 
Published: November 2022

A hill slope is a part of a mining, especially mining by Open Pit Method. The TB 1.42 Pemali PT Timah (Persero)Tbk, which is often referred as the TB 1.42 applies the open it method in its mining, hence the condition of the hill slope greatly influences the mining Safety because hill slope instability can cause avalance. Hance, the hill slope stability has to be calculated.The calculation is performed to get the value of the safety factor (FK) and to understand the slope’s condition. This calculation can be done using yheFelleniusMethod, either manually or using,SoftwareSlideRocscience 6.0. The FelleniusMethod requires the shear strength parameter in the calculation, therefore a laboratory testing is performed using direct shear test ASTM D-3064-04. This test generates the value of cohesion (c),the angle of internal friction (ɸ) and the soil density (γ) of a soil sample taken from the field.Basedon the research the front south slope TB 1.42 Pemali have sandy loam lithology (Slope LT01), clay (Slope LT02 dan LT03), and gravelly clay (slope LT04). Based on the Fellenius Method, the value of FK for the slope is affected by the slope’s angle and shear strength parameter ( c and ɸ). The analysis conducted in this study showed that of the four slopes that are observed, there are two unstable slopes, which are slope LT02 with FK amounted to 0,809 (manual) and 0,877 (slide), which is unstable ; and the slope LT03 with FK amounted to 1,056 (manual) and 1,070 (slide), which is in critical condition. In order to solve the instability of the slope, PT Timah (Persero) Tbk. Can alter the slope’s geometry and install a grouted tieback anchors at unstable slopes.
Metformin use and mortality and length of stay among hospitalized patients with type 2 diabetes and COVID-19: A multiracial, multiethnic, urban observational study
Authors: Miao Emily , Zhang Kaleena , Liu Jianyou , Lin Juan , Yoo Donna , George Claudene J. 
Published: November 2022

IntroductionDiabetes mellitus is a common comorbidity among patients with coronavirus disease 2019 (COVID-19). Diabetic patients with COVID-19 have a two-fold increased risk of death and tend to have more severe infection compared to the general population. Metformin, a first-line medication for diabetes management, has anti-inflammatory and immunomodulatory effects. Previous studies focusing on metformin and COVID-19 clinical outcomes have had mixed results, with some showing a mortality benefit or decreased complications with metformin use. To date, few studies have analyzed such outcomes among a diverse, multiracial community.MethodsThis was a retrospective review of patients with Type 2 diabetes and a confirmed COVID-19 infection admitted to an urban academic medical center from January 1, 2020 to May 7, 2020. Baseline characteristics were collected. The primary outcomes of the study were in-hospital mortality and length of stay (LOS).ResultsA total of 4462 patients with Type 2 diabetes and confirmed COVID-19 were identified. 41.3% were Black, and 41.5% were Hispanic. There were 1021 patients in the metformin group and 3441 in the non-metformin group. Of note, more participants in the metformin group had comorbid disease and/or advanced diabetes. We found no statistically significant differences between the metformin and non-metformin group in in-hospital mortality (28.1% vs 25.3%, P=0.08) or length of hospital stay in days (7.3 vs. 7.5, P=0.59), even after matching patients on various factors (29.3% vs. 29.6%, P=0.87; 7.7 vs. 8.1, P=0.23).ConclusionWhile patients had more comorbid disease and advanced diabetes in the metformin group, there were no significant differences with regard to in-hospital mortality or length of stay due to COVID-19 compared to the non-metformin group. Prospective studies are needed to determine if there is clinical benefit for initiating, continuing, or re-initiating metformin in patients hospitalized with COVID-19.
Dissecting lncRNA-mRNA competitive regulatory network in human islet tissue exosomes of a type 1 diabetes model reveals exosome miRNA markers
Authors: Fang Tian , Xue Gong , Jianjun Wu , Wei Long , Xiaomeng Zhang , Fan Yang 
Published: November 2022

BackgroundEmerging evidence shows that exosomes play a crucial role in the occurrence and development of diabetes and its complications. The molecules in exosomes can be regarded as important markers for the diagnosis of diseases. However, it is presently unclear the pathological association mechanism between exosomes and diabetes.ResultsIn this study, transcriptome data and lncRNA regulatory association data of human pancreatic islet-derived exosome were integrated to construct the ceRNA network. Network analysis revealed that lncRNA with differential expression were primarily involved in islet insulin secretion signaling pathways, including Hippo, TGF-beta, Wnt, FOXO, Neurotrophin and ErbB signaling pathway. Further, combined with miRNA mediated competitive regulation and differential expression analysis results, potential markers of diabetes were revealed and validated in independent datasets. Finally, we analyzed the mechanisms of diabetes based on the competitive regulatory association and function of lncRNA.ConclusionOur results suggest that lncRNA such as lncRNA PVT1, LINC00960 and hsa-miR-107 might be involved in inflammation response in T1DM, and the former lncRNA chose in the present study may serve as novel biomarkers and potential targets for the diagnosis and treatment of T1DM.
Determination of iFGF23 Upper Reference Limits (URL) in healthy pediatric population, for its better correct use
Authors: Brescia Vincenzo , Fontana Antonietta , Lovero Roberto , Capobianco Carmela , Marsico Stella Vita , De Chirico Tiziana , Pinto Carla , Varraso Lucia , Cazzolla Angela Pia , Di Serio Francesca 
Published: November 2022

BackgroundThe measurement of Fibroblast growth factor 23 (FGF23) may be useful in the diagnosis and management of abnormal phosphate metabolism in both patients with preserved renal function or with chronic kidney disease (CKD). FGF-23 tests differ considerably by molecule assayed (iFGF23 or cFGF23), analytical performance and reference ranges. We establish iFGF23 Upper Reference Limits (URL) in apparently healthy pediatric individuals using automated immunochemiluminescent assay.MethodsWe measured the levels of plasma iFGF23 from 115 samples from apparently healthy pediatric subjects [59 (51.3%) individuals were male; median age 10 years (range 1–18)] included in an observational study conducted at Policlinico University Hospital of Bari. The method used for the iFGF23 assay was immunochemiluminescent sandwich assay developed by DiaSorin on the Liaison XL platform. Statistical calculation of 95% reference interval, right-sided (CLSI C28-A3) and verification of age and sex covariables was performed for the calculation of the URL.ResultsThe URL concentration of iFGF23 was 61.21 pg/mL (58.63 to 63.71, 90% CI). No significant differences were found between the median concentrations of iFGF23 differentiated by sex and age.ConclusionsThe dosage of iFGF23 is important both for the differential diagnosis of the various forms of rickets, and for the subsequent monitoring of the effectiveness of drug treatment. We have established the URL for the iFGF23 Liaison test in apparently healthy pediatric subjects. The availability of iFGF23 pediatric reference values will allow a better clinical use of the test.