bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synergy of arsenic with smoking in causing cardiovascular disease mortality: A cohort study with 27 follow-up years in China
Authors: Jia Xin-Hua , Su Zheng , Zhao Fang-Hui , Zhou Qing-Hua , Fan Ya-Guang , Qiao You-Lin 
Published: December 2022

BackgroundTo explore the patterns of the exposure-response relationship between arsenic exposure and cardiovascular disease (CVD) mortality and investigate the effect of cigarette smoking on the association.MethodsSeven thousand seven hundred thirty-five tin miners with at least 10 years of arsenic exposure were enrolled since 1992 and followed up for 27 years. Each individual's air arsenic exposure at workplace was calculated by time weighted average arsenic concentration × exposure months. Detailed information on smoking was collected at baseline, and information on smoking status was collected for five consecutive years from 1992 to 1996. Hazard ratio (HR) and 95% confidence interval (CI) for the risk of CVD were estimated using Cox proportional hazards models.ResultsA total of 1,046 CVD deaths occurred in this cohort over 142,287.7 person-years of follow up. We firstly reported that for equal cumulative exposure, participants exposed to higher concentrations over shorter duration had a higher risk of CVD mortality than those exposed to lower concentration over longer duration. The HR and 95% CI were 1.38 (95%CI: 1.03–1.85) in participants exposed to arsenic concentration (45.5–99.5 mg/m3), 1.29 (95%CI: 1.02–1.67) in 99.5–361.0 mg/m3. Further, participants with age at first exposure &lt;18 years had a significantly higher risk of morality from CVD, cerebrovascular and heart diseases than those with ≥18 years. Finally, all synergy indices were greater than 1 (range, 1.11–2.39), indicating that the joint effect of arsenic exposure and cigarette smoking on CVD mortality was greater than the sum of their individual effect.ConclusionsExposure to air arsenic at workplace is adversely associated with mortality from CVD, especially among smokers younger than 18 years and smokers.
Becoming an Agile Change Conductor
Authors: Mehta Jade , Aalsma Matthew C. , O'Brien Andrew , Boyer Tanna J. , Ahmed Rami A. , Summanwar Diana , Boustani Malaz 
Published: December 2022

BackgroundIt takes decades and millions of dollars for a new scientific discovery to become part of clinical practice. In 2015, the Center for Health Innovation &amp; Implementation Science (CHIIS) launched a Professional Certificate Program in Innovation and Implementation Sciences aimed at transforming healthcare professionals into Agile Change Conductors capable of designing, implementing, and diffusing evidence-based healthcare solutions.MethodIn 2022, the authors surveyed alumni from the 2016–2021 cohorts of the Certificate Program as part of an educational quality improvement inquiry and to evaluate the effectiveness of the program.ResultsOf the 60 alumni contacted, 52 completed the survey (87% response rate) with 60% of graduates being female while 30% were an under-represented minority. On a scale from 1 to 5, the graduates agreed that the certificate benefited their careers (4.308 with a standard deviation (SD) of 0.612); expanded their professional network (4.615, SD of 0.530); and had a large impact on the effectiveness of their leadership (4.288, SD of 0.667), their change management (4.365, SD of 0.742), and their communication (4.392, SD of 0.666). Graduates claimed to use Agile Processes (Innovation, Implementation, or Diffusion), storytelling, and nudging weekly. On a scale from 0 to 10 where 10 indicates reaching a mastery, the average score for different Agile competencies ranged from 5.37 (SD of 2.80) for drafting business proposals to 7.77 (SD of 1.96) for self-awareness. For the 2020 and 2021 cohorts with existing pre and post training competency data, 22 of the 26 competencies saw a statistically significant increase.ConclusionThe Graduate Certificate has been able to create a network of Agile Change Conductors competent to design, implement, and diffuse evidence-based care within the healthcare delivery system. Further improvements in building dissemination mastery and program expansion initiatives are advised.
Prevalence and correlates of overweight and obesity among under-five children in Egypt
Authors: Osei Bonsu Emmanuel , Addo Isaac Yeboah 
Published: December 2022

BackgroundEvidence suggests that Egypt, a country in North Africa, has a significant number of children at serious risk of excess body weight. Yet, there is a dearth of studies on overweight and obesity among children under 5 years in the country. This study examined the prevalence and correlates of overweight and obesity among under-five children in Egypt.MethodsData were retrieved from the latest (2008 and 2014) Egypt Demographic and Health Surveys (EDHS). A total of 42,568 children under 5 years were included. The prevalence of overweight and obesity was described using proportions whereas the factors associated with the prevalence were examined using logistic regression.ResultsOf the 42,568 children under 5 years, about one in every six (17%) were overweight or obese. Children aged 19–37 months, those with birth weights &gt;4 kg, those given large portions of protein foods (eggs and meat), and those whose mothers were in the rich wealth quintile had significant risks of overweight or obesity.ConclusionOverweight and obesity are highly prevalent among children under 5 years in Egypt. Interventions developed to address these two overnutrition indicators in Egypt need to consider variations in risk factors across age, birth weight, food types and portions, and maternal wealth status.
Association between healthy food environment and metabolic syndrome, waist circumference, and systolic blood pressure in older adults in Southern Brazil
Authors: Souza Bianca Bittencourt de , Quialheiro Anna , Correa Elizabeth Nappi , Rech Cassiano Ricardo , Giehl Maruí Weber Corseuil , d’Orsi Eleonora 
Published: December 2022

The aim of this study was to investigate the association between healthy food outlet proximity, metabolic syndrome (MS), and two of its components, waist circumference (WC) and systolic blood pressure (SBP), in older adults (63–107 years old, median age 73 years) living in Florianópolis, South Brazil in 2013–2014. This is a cross-sectional analysis of the second wave of the EpiFloripa Aging Cohort Study. Individual-level data on MS, WC, SBP, and socio-demographic and health-related characteristics were collected from face to face interviews. The healthy food environment was assessed via the number and types of establishments present. The residences of older adult participants were georeferenced using Geographical Information System (GIS) software. The number of each type of food establishment in a 500 m buffer around the each residence was determined. Multivariate linear regression was used to test association between food outlet proximity and continuous outcomes (SBP and WC), and multiple logistic regression was used to examine the relations between the predictor variables and the dichotomous outcome of MS (yes/no). The study revealed that greater frequency of supermarkets and restaurants in the neighborhood was associated with a lower likelihood of having MS. WC was lower in individuals living in places with greater availability of greengrocers’ shops and restaurants. The results demonstrated that the number of establishments in a neighborhood is associated with cardiometabolic outcomes, and the likelihood of MS and increased WC is lower for older adults who live in neighborhoods with more access to establishments that sell foundational components of a healthy diet.
Black soldier fly larvae used for environmental enrichment purposes: Can they affect the growth, slaughter performance, and blood chemistry of medium-growing chickens?
Authors: Bongiorno Valentina , Gariglio Marta , Zambotto Valeria , Cappone Eleonora Erika , Biasato Ilaria , Renna Manuela , Forte Claudio , Coudron Carl , Bergagna Stefania , Gai Francesco , Schiavone Achille 
Published: December 2022

IntroductionThis research has been aimed at evaluating the effects of live black soldier fly larvae (BSFL) (Hermetia illucens) on the growth, slaughtering performance, and blood parameters of medium-growing chickens.MethodsA total of 240, 28-day-old, Label Rouge Naked Neck chickens were allotted to four experimental groups, according to the gender (males-females) and to the absence (control group, C) or presence (larvae group, L) of a dietary supplementation with 10% live BSFL, on the basis of the expected average daily feed intake (ADFI) (6 replicates/diet, 10 chickens/replicate). The birds were weighed weekly, and the feed consumption was recorded to calculate the average live weight, feed conversion ratio (FCR), average daily gain (ADG), and the ADFI. At 82 days of age, 2 birds/replicate (12 birds/diet) were selected and slaughtered. The blood samples were collected, and the carcass traits (carcass, breast, thigh, and organ weights and yields) were assessed.Results and discussionsOverall, the administered live BSFL did not impair the growth and slaughtering performance, or the blood traits, while the C females showed a better FCR than the treated ones (P &lt; 0.05). The live BSFL consumption time was longer for the females than for the males (P &lt; 0.001). The weight of the immune organs (spleen and bursa of Fabricius) increased as the live BSFL supplementation increased (P &lt; 0.05). Furthermore, the provision of live BSFL reduced the gamma glutamyl transferase (GGT, U/l) activity content in the blood (P &lt; 0.05). Finally, both the leukocytes (%) and the monocytes (%) were more abundant in the C groups than in the larvae ones (P &lt; 0.05 and P &lt; 0.01, respectively). In short, the supplementation of live BSFL can be used successfully as an environmental enrichment, without affecting the growth performance of male birds. Furthermore, the immune organ activity could be enhanced by the provision of live BSFL.
PARP-1 genetic polymorphism associated with radiation sensitivity of non-small cell lung cancer
Authors: Wang Hetong , Xie Haitao , Wang Shuying , Zhao Jiaying , Gao Ya , Chen Jun , Zhao Yuxia , Guo Genyan 
Published: December 2022

About 70% of non-small cell lung cancer (NSCLC) patients require radiotherapy. However, due to the difference in radiation sensitivity, the treatment outcome may differ for the same pathology and choice of treatment. Poly (ADP-ribose) polymerase 1 (PARP-1) is a key gene responsible for DNA repair and is involved in base excision repair as well as repair of single strand break induced by ionizing radiation and oxidative damage. In order to investigate the relationship between PARP-1 gene polymorphism and radiation sensitivity in NSCLC, we collected 141 primary NSCLC patients undergoing three-dimensional conformal radiotherapy. For each case, the gross tumor volumes (GTV) before radiation and that after 40 Gy radiation were measured to calculate the tumor regression rate. TaqMan real-time polymerase chain reaction was performed to genotype the single-nucleotide polymorphisms (SNPs). Genotype frequencies for PARP-1 genotypes were 14.2% for C/C, 44.7% for C/G and 41.1% for G/G. The average tumor regression rate after 40 Gy radiation therapy was 35.1% ± 0.192. Tumor regression rate of mid-term RT of C/C genotype was 44.6% ± 0.170, which was higher than that of genotype C/G and G/G (32.4% ± 0.196 and 34.8% ± 0.188, respectively) with statistical significance (F = 3.169 p = 0.045). The higher tumor regression rate in patients with C/C genotype suggested that G allele was a protective factor against radiation therapy. Using the median tumor regression rate of 34%, we divided the entire cohort into two groups, and found that the frequency distribution of PARP-1 gene rs3219073 had significant difference between these two groups (p &lt; 0.05). These results showed that PARP-1 gene polymorphism may affect patient radiation sensitivity and predict the efficacy of radiotherapy. It therefore presents an opportunity for developing new therapeutic targets to improve radiotherapy outcome.
Fabrication and Underwater Testing of a Vector Hydrophone Comprising a Triaxial Piezoelectric Accelerometer and Spherical Hydrophone
Authors: Roh Taehoun , Yeo Hong Goo , Joh Cheeyoung , Roh Yongrae , Kim Kyungseop , Seo Hee-seon , Choi Hongsoo 
Published: December 2022

A vector hydrophone is an underwater acoustic sensor that can detect the direction of a sound source. Wide-band characteristics and high sensitivity enhance the performance of underwater surveillance systems in complex environments. A vector hydrophone comprising a triaxial piezoelectric accelerometer and spherical hydrophone was fabricated and tested in the air and underwater. The vector hydrophone was designed to exceed the quantitative figures of merit (i.e., receiving voltage sensitivity and bandwidth) of commercially available hydrophones. Accelerometer performance was enhanced by placing a pair of piezoelectric single crystals on each axis and modifying the seismic mass material. The receiving voltage sensitivity of the omnidirectional hydrophone was approximately −160 dB relative to 1 V/μPa with the amplifier in water; the sensitivity of the accelerometer exceeded 300 mV/g in air and −215 dB relative to 1 V/μPa underwater over the frequency range of interest. The receiving directivity of the vector hydrophone was validated underwater, which confirmed that it could detect the direction of a sound source.
L’ordre des Prêcheurs dans l’iconographie méridionale et ses modes de représentation
Authors: Russo Daniel 
Published: December 2022

The Order of Preachers in Southern French Iconography and its Modes of Representation.
Dominican memory partly rests on an iconographie tradition formed after 1250, when the Order somewhat moved away from the ascetic path of its beginnings. From the second half of the 13th century on, figurative representations spread in monasteries. Their role was to convey the Preachers’ community and the life it intended to lead by praising the Order’s apostolic mission within Church. In the 14th century, the Order felt it was and showed itself as, particularly through Saint Thomas, the guardian of divine word ; it introduced itself as successor of the apostles and thus on the same level as bishops. In the 15th century, the Preachers’ past, as portrayed, eventually identified itself with the past of Christianity, with a strong emphasis on the repression of heresies. The representation of Saint Dominic then became a very common topic again when Observance was established, as guarantee of reform and rebuilding. Yet, even if the Order of Preachers recognized itself in the saints it honoured, it did not arouse the people’s devotion and, in Dominican monasteries themselves, most of the chapels and churches bore the names of traditional intercessors.
Trust And Governance in a Rethinking of Classical Knowledge Management Paradigms: Toolkits for Public Sector During the COVID-19 Emergency
Authors: Antonucci Gianluca , Berardi Marco , Ziruolo Andrea , Fontana Fabrizia 
Published: December 2022

The post Covid-19 world is characterized by new technologies and a smart city approach. For this reason, the public sector must shift from the classic paradigms to a new way, following a Knowledge Management (KM) approach, to perform its role in dealing with emergency situations. Starting from classical KM models, we conducted a regional case study, showing how the process of rethinking is boosted by citizens’ needs and pushed by the trust of the stakeholders in the central authority. In fact, as highlighted by part of the international literature, local authorities’ planning aims to achieve public value and alignment between stakeholders and policy making represents one of the main goals to be achieved. With an OLS regression we estimated the correlation between the trust of citizens and the statutory actions taken by central and peripheral government, showing that only with the alignment of public policies and the will of the citizens is it possible to overcome a crisis. Moreover, we underline the gaps in the literature and the missing links, with the aim of creating a KM model that can also be applied in the near future.
PELAKSANAAN SENAM OTAK PADA WANITA POST MENOPAUSE KERJASAMA DENGAN PUSKESMAS JUANDA
Authors: Rusli Herdin 
Published: December 2022

Abstrak: Kelurahan Air Hitam, Samarinda Ulu merupakan daerah di Kalimantan Timur dengan jumlah fisioterapis di samarinda leih dari 10 orang. post menopause usia 65 tahun terjadi penurunan produksi hormon estrogen sehingga mengakibatkan penurunan kadar neurotransmiter yang berperan dalam fungsi ingatan yaitu asetilkolin, glutamat, neurotrophic, dan endorfin yang berada di otak. senam otak dapat memperlancar aliran darah dan oksigen ke otak, serta meningkatkan daya ingat dan konsentrasi . Metode yang digunakan adalah demonstrasi dan membimbing wanita post menopause untuk melakukansenam otak,mengedukasi dan menasehati penderita untuk meningkatkan aktivitas fisik. Hasil yang dicapai adalah senam otak yang mana selain tubuh tetap sehat tp juga bisa menjaga an menyeimbangkan otak kanan dan kiri sehingga masalah penurunan daya ingat yang sebagian besar terjadi pada ibu-ibu yang sudah menopause dapat teratasi.
A “ILUSÃO” DA TRANSPARÊNCIA DO ESPAÇO E A “FÉ CEGA” NO PLANEJAMENTO URBANO
Authors: Carlos Ana Fani Alessandri 
Published: December 2022

O texto foca o papel do espaço no movimento de realização do processo de acumulação num momento em que se constata a passagem da hegemonia do capital industrial ao capital financeiro tendo como orientação a mundialização, que se revela num mundo, tendencialmente urbano. Imersos na “aparente transparência do espaço” os estudos sobre o espaço urbano têm abandonado a análise crítica da realidade em favor do planejamento.
PUNK E HIP-HOP NA CIDADE
Authors: Turra Neto Nécio 
Published: December 2022

Procuro abordar, neste artigo, o processo de constituição, na cidade de Guarapuava/PR, dos movimentos punk e hip-hop, com vistas a oferecer uma possibilidade de abordagem, na Geografia, dos movimentos sociais constituídos por atores jovens. Inicialmente, apresento, de forma resumida, a trajetória de constituição do próprio lugar que, em certo momento, contou com condições geo-históricas favoráveis à aterrissagem desses movimentos juvenis transterritoriais. Depois, apresento uma breve história do surgimento e difusão do punk e do hip-hop pelo mundo. Por fim, trago uma interpretação das trajetórias desses movimentos em Guarapuava, traçando o processo de constituição das redes localizadas de sociabilidade e de territorialização de cada movimento na cidade, que fizeram com que, no lugar, se constituíssem novos sujeitos políticos, em diálogo e em conflito com aqueles já presentes. o centro do trabalho é o estudo comparativo da difusão, territorialização e formação das redes de sociabilidade de ambos os movimentos.
ATIVISMOS SOCIOCULTURAIS NOS BAIRROS POPULARES DE SALVADOR
Authors: Serpa Angelo 
Published: December 2022

Busca-se, com o presente artigo, explicitar, a partir de estudos empíricos nos bairros populares de Salvador-BA, as interfaces entre ativismos sociais e as manifestações da cultura popular no cotidiano dessas áreas, atentando-se em especial para as relações entre cultura e política e sua espacialização na cidade contemporânea. Essas formas de articulação nem sempre ganham status de “movimento social” ou de “movimentos associativistas”, mas conferem caráter particular às respectivas áreas de ocorrência, demonstrando que são múltiplos também os modos de organização dos agentes e grupos nos bairrospopulares da cidade. Isso pode demonstrar também novas formas de relações sociais, articuladas em “rede”, e, em especial, seu significado em uma esfera pública renovada e pensada sob uma perspectiva de articulação entre cultura e política na reprodução da vida cotidiana, nos lugares concretos da cidadecontemporânea. Como conclusão, enfatizamos a importância do conceito de redes de sociabilidade/solidariedade para análise desses ativismos que, na Geografia Urbana, justificam uma abordagem sociocultural e espacial dessas novas formas de organização que surgem nos bairros populares de nossas cidades.
Comparison of Maternal and Perinatal Outcomes of Pregnancy with Systemic Lupus Erythematosus in Planned Referrals Compared to Emergency Referrals Based on the Maternal Fetal Triage Index at Dr. Kariadi General Hospital, Semarang, Indonesia
Authors: Rachmadhini Gayuh Tunggal , Rakhma Yanti Hellmi  , Yuli Trisetiyono  , Arufiadi Anityo Mochtar  , Endy Cahyono  , Ratnasari Dwi Cahyanti  , Putri Sekar Wiyati  
Published: December 2022

Background: Systemic lupus erythematosus (SLE) is an autoimmune disease that attacks the skin and the musculoskeletal, kidney, neuropsychiatric, hematological, cardiovascular, pulmonary, and reproductive systems. In pregnancies with SLE, early referral to the hospital with the involvement of obstetricians and rheumatologists, and other specialists as needed, as well as individual management plans, regular reviews, and early recognition of flares and complications, are important. This study aimed to determine the differences in maternal and perinatal outcomes referred by planned referrals compared to emergency referrals, especially in pregnant patients with SLE.
Methods: This study was an analytic observational study with a retrospective cohort approach. A total of 40 subjects participated in this study. Data analysis using SPSS software was carried out univariate and bivariate to examine the relationship between types of referrals and maternal and perinatal outcomes.
Results: There were significant differences between the types of emergency referrals and planned referrals in the variable incidence of preeclampsia and SLE exacerbations. There were no significant differences between the types of emergency referrals and planned referrals on the variable incidence of lupus nephritis, maternal death, premature delivery, fetal growth restriction, fetal death, and the incidence of neonatal lupus syndrome.
Conclusion: The incidence of severe preeclampsia and SLE exacerbation was lower in planned referrals compared to emergency referrals in pregnant patients with SLE at Dr. Kariadi General Hospital, Semarang, Indonesia.
Pengaruh Imaginary Prisons Piranesi terhadap Bentuk Set Tangga dalam Film Seri Squid Game
Authors: Amirah Charissa Myandra , Indrajaya Ferdinand , Kinanti Zhevanya Bintang , Fransiska Yessa , Yoshida Manaka 
Published: December 2022

<p class="p1">Serial drama Squid Game adalah salah satu film seri yang sempat populer dan meroket pesat melalui layanan streaming Netflix. Squid Game berhasil mencuri hati para penonton melalui keunikan konsep dan alur ceritanya. Keunikan konsep dan alur cerita tersebut turut terbangun oleh keputusan artistik dalam mise en scène-nya. Mise en scène menunjuk pada tata kelola set latar beserta propertinya dalam sebuah pertunjukan teater ataupun film. Salah satu bagian mise en scène dari film tersebut yang akan menjadi perhatian dalam tulisan ini adalah bentuk dari anak tangganya. Bentuknya yang berliku dan nampak tak berujung mengingatkan penulis pada rangkaian lukisan Imaginary Prisons dari Giovanni Battista Piranesi. Bagi penulis, perancangan bentuk anak tangga dalam Squid Game merupakan warisan Piranesi dalam bentuk film seri masa kini. Hwang Dong Hyuk sendiri, sang sutradara Squid Game, sesungguhnya tidak secara langsung terinspirasi oleh Piranesi. Ia pertama-tama dipengaruhi oleh karya-karya dari M.C. Escher yang berkiblat ke Imagine Prison dari Piranesi tersebut. Pemaparan lebih lanjut tentang warisan Piranesi dalam film seri Squid Game akan menjadi fokus dalam penulisan makalah ini. Secara sistematis, pemaparan akan disampaikan melalui beberapa tahapan. Elaborasi dan analisis tentang Imaginary Prisons dari Piranesi akan menjadi tahap awal pembahasan. Kedua, tulisan akan membahas beberapa karya dari M.C. Escher yang turut dipengaruhi Piranesi dan akhirnya turut menginspirasi perancangan bentuk set tangga dari Squid Game. Terakhir, pemaparan yang lebih konklusif untuk menunjukkan keeratan hubungan antara Imaginary Prisons dengan Squid Game akan disampaikan.</p>