bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multiple Angle Observations Would Benefit Visible Band Remote Sensing Using Night Lights
Authors: Kyba Christopher C. M. , Aubé Martin , Bará Salvador , Bertolo Andrea , Bouroussis Constantinos A. , Cavazzani Stefano , Espey Brian R. , Falchi Fabio , Gyuk Geza , Jechow Andreas , Kocifaj Miroslav , Kolláth Zoltán , Lamphar Héctor , Levin Noam , Liu Shengjie , Miller Steven D. , Ortolani Sergio , Jason Pun Chun Shing , Ribas Salvador José , Ruhtz Thomas , Sánchez de Miguel Alejandro , Schneider Mathias , Shrestha Ranjay Man , Simoneau Alexandre , So Chu Wing , Storch Tobias , Tong Kai Pong , Tuñón Milagros , Turnshek Diane , Walczak Ken , Wang Jun , Wang Zhuosen , Zhang Jianglong 
Published: June 2022

AbstractThe spatial and angular emission patterns of artificial and natural light emitted, scattered, and reflected from the Earth at night are far more complex than those for scattered and reflected solar radiation during daytime. In this commentary, we use examples to show that there is additional information contained in the angular distribution of emitted light. We argue that this information could be used to improve existing remote sensing retrievals based on night lights, and in some cases could make entirely new remote sensing analyses possible. This work will be challenging, so we hope this article will encourage researchers and funding agencies to pursue further study of how multi‐angle views can be analyzed or acquired.
The Effects of Surface Mixers on Stratification, Dissolved Oxygen, and Cyanobacteria in a Shallow Eutrophic Reservoir
Authors: Slavin E. I. , Wain D. J. , Bryant L. D. , Amani M. , Perkins R. G. , Blenkinsopp C. , Simoncelli S. , Hurley S. 
Published: June 2022

AbstractTop‐down surface mixers are increasingly used in drinking water reservoirs to prevent the development of stratification, control cyanobacteria, and limit sediment release of soluble manganese. A targeted field investigation enabled the discrimination of artificial mixing by surface mixers from wind and convection in a shallow (6.6 m), eutrophic drinking water reservoir. Top‐down surface mixers were effective at reducing vertical temperature and dissolved oxygen gradients over a 20 m radius, within which turbulent kinetic energy (TKE) input from the mixers exceeded the maximum TKE contribution from wind and convection. Meteorological conditions appeared to have a stronger influence beyond a 60 m radius from the mixers. Near‐bed velocities measured using an Acoustic Doppler Velocimeter (ADV) ∼ 30 m north of the mixers were significantly lower when the mixers were not operating; when operating, ADV signal amplitude showed localized sediment resuspension. Cyanobacteria cell counts were high throughout the reservoir but counts of low‐light adapted Planktothrix sp. were highest near the mixers, indicating mixer operation may improve growing conditions for Planktothrix. While the destratification goal of mixers was accomplished locally, the limited range of influence left >90% of the reservoir subject to diurnal stratification, anoxia, and potential internal loading of inorganic nutrients and soluble metals, restricting mixer effectiveness as an in‐reservoir management technique to improve raw water quality in shallow systems.
Predominant Type of Dust Storms That Influences Air Quality Over Northern China and Future Projections
Authors: Li Jiandong , Hao Xin , Liao Hong , Yue Xu , Li Hua , Long Xin , Li Nan 
Published: June 2022

AbstractDust storms (DSs) originating in East Asia impact ecosystems, climate, and public health in China. Although DS frequencies have declined since the 1950s, extreme DSs in spring 2021 had major effects on air quality over northern China. Based on daily DS records in spring during 1979–2021 and K‐means clustering, we define two DS types (T1 and T2) in northern China, accounting for 18.7% and 81.3% of DSs, respectively. T1 DSs, originating mainly in the Gobi Desert, predominantly influence air quality in northern China, while T2 DSs mainly influence northwestern China near the Taklimakan Desert. T1 and T2 DSs are driven by major synoptic systems including the Mongolian cyclone and cold fronts, respectively. Based on predictions of the Climate Models Intercomparison Project Phase Six, we demonstrate that the spring DS frequency would decrease during 2020–2100 under the shared socioeconomic pathway (SSP) 585 scenario but would fluctuate with decadal variability under the SSP126 scenario. Our results indicate that spring DSs can be triggered by a range of mechanisms, with distinct impacts on air quality.
CitcomSVE: A Three‐Dimensional Finite Element Software Package for Modeling Planetary Mantle’s Viscoelastic Deformation in Response to Surface and Tidal Loads
Authors: Zhong Shijie , Kang Kaixuan , A Geruo , Qin Chuan 
Published: June 2022

AbstractThis article presents a comprehensive benchmark study for the newly updated and publicly available finite element code CitcomSVE for modeling dynamic deformation of a viscoelastic and incompressible planetary mantle in response to surface and tidal loading. A complete description of CitcomSVE’s finite element formulation including calculations of the sea‐level change, polar wander, apparent center of mass motion, and removal of mantle net rotation is presented. The 3‐D displacements and displacement rates and the gravitational potential anomalies are solved with CitcomSVE for three benchmark problems using different spatial and temporal resolutions: (a) surface loading of single harmonics, (b) degree‐2 tidal loading, and (c) the ICE‐6G GIA model. The solutions are compared with semi‐analytical solutions for error analyses. The benchmark calculations demonstrate the accuracy and efficiency of CitcomSVE. For example, for a typical ICE‐6G GIA calculation with a 122‐ky glaciation‐deglaciation history, time increment of 100 years, and ∼50 km (or ∼0.5°) surface horizontal resolution, it takes ∼4.5 hr on 96 CPU cores to complete with about 1% and 5% errors for displacements and displacement rates, respectively. Error analyses shows that CitcomSVE achieves a second order accuracy, but the errors are insensitive to temporal resolution. CitcomSVE achieves the parallel computational efficiency >75% for using up to 6,144 CPU cores on a parallel supercomputer. With its accuracy, computational efficiency and its open‐source public availability, CitcomSVE provides a powerful tool for modeling viscoelastic deformation of a planetary mantle with 3‐D mantle viscous and elastic structures in response to surface and tidal loading problems.
Global Changes in Water Vapor 1979–2020
Authors: Allan Richard P. , Willett Kate M. , John Viju O. , Trent Tim 
Published: June 2022

AbstractGlobal‐scale changes in water vapor and responses to surface temperature variability since 1979 are evaluated across a range of satellite and ground‐based observations, a reanalysis (ERA5) and coupled and atmosphere‐only CMIP6 climate model simulations. Global‐mean column integrated water vapor increased by 1%/decade during 1988–2014 in observations and atmosphere‐only simulations. However, coupled simulations overestimate water vapor trends and this is partly explained by past studies showing that internal climate variability suppressed observed warming in this period. Decreases in low‐altitude tropical water vapor in ERA5 and ground‐based observations before around 1993 are considered suspect based on inconsistency with simulations and increased column integrated water vapor in microwave satellite data since 1979. Atmospheric Infra‐red Sounder satellite data does not capture the increased tropospheric water vapor since 2002 shown by other satellite, reanalysis, and model products. However, global water vapor responses to interannual surface temperature variability are consistent across data sets with increases of ∼4%–5% near the surface and 10%–15% at 300 hPa for each 1°C increase in global surface temperature. Global water vapor responses are explained by thermodynamic amplification of upper tropospheric temperature changes and the Clausius Clapeyron temperature dependence of saturation vapor pressure that are dominated by the tropical ocean responses. Upper tropospheric moistening is larger in climate model simulations with greater upper tropospheric warming.
Congestus Mode Invigoration by Convective Aggregation in Simulations of Radiative‐Convective Equilibrium
Authors: Sokol Adam B. , Hartmann Dennis L. 
Published: June 2022

AbstractThis study examines how the congestus mode of tropical convection is expressed in numerical simulations of radiative‐convective equilibrium (RCE). We draw insights from the ensemble of cloud‐resolving models participating in the RCE Model Intercomparison Project (RCEMIP) and from a new ensemble of two‐dimensional RCE simulations. About half of the RCEMIP models produce a congestus circulation that is distinct from the deep and shallow modes. In both ensembles, the congestus circulation strengthens with large‐scale convective aggregation, and in the 2D ensemble this comes at the expense of the shallow circulation centered at the top of the boundary layer. Congestus invigoration occurs because aggregation dries out the upper troposphere, which allows moist congestus outflow to undergo strong radiative cooling. The cooling generates divergence that promotes continued congestus overturning (a positive feedback). This mechanism is fundamentally similar to the driving of shallow circulations by radiative cooling at the top of the surface boundary layer. Aggregation and congestus invigoration are also associated with enhanced static stability throughout the troposphere, but a modeling experiment shows that enhanced stability is not necessary for congestus invigoration; rather, invigoration itself contributes to the stability increase via its impact on the vertical profile of radiative cooling. Changes in entrainment cooling are also found to play an important role in stability enhancement, as has been suggested previously. When present, congestus circulations have a large impact on the mean RCE atmospheric state; for this reason, their inconsistent representation in models and their impact on the real tropical atmosphere warrant further scrutiny.
Hemodynamic consequences of respiratory interventions in preterm infants
Authors: Sehgal Arvind , Ruoss J. Lauren , Stanford Amy H. , Lakshminrusimha Satyan , McNamara Patrick J. 
Published: June 2022

AbstractAdvances in perinatal management have led to improvements in survival rates for premature infants. It is known that the transitional period soon after birth, and the subsequent weeks, remain periods of rapid circulatory changes. Preterm infants, especially those born at the limits of viability, are susceptible to hemodynamic effects of routine respiratory care practices. In particular, the immature myocardium and cardiovascular system is developmentally vulnerable. Standard of care (but essential) respiratory interventions, administered as part of neonatal care, may negatively impact heart function and/or pulmonary or systemic hemodynamics. The available evidence regarding the hemodynamic impact of these respiratory practices is not well elucidated. Enhanced diagnostic precision and therapeutic judiciousness are warranted. In this narrative, we outline (1) the vulnerability of preterm infants to hemodynamic disturbances (2) the hemodynamic effects of common respiratory practices; including positive pressure ventilation and surfactant therapy, and (3) identify tools to assess cardiopulmonary interactions and guide management.
The cellular composition and function of the bone marrow niche after allogeneic hematopoietic cell transplantation
Authors: Peci Flavia , Dekker Linde , Pagliaro Anna , van Boxtel Ruben , Nierkens Stefan , Belderbos Mirjam 
Published: June 2022

AbstractAllogeneic hematopoietic cell transplantation (HCT) is a potentially curative therapy for patients with a variety of malignant and non-malignant diseases. Despite its life-saving potential, HCT is associated with significant morbidity and mortality. Reciprocal interactions between hematopoietic stem cells (HSCs) and their surrounding bone marrow (BM) niche regulate HSC function during homeostatic hematopoiesis as well as regeneration. However, current pre-HCT conditioning regimens, which consist of high-dose chemotherapy and/or irradiation, cause substantial short- and long-term toxicity to the BM niche. This damage may negatively affect HSC function, impair hematopoietic regeneration after HCT and predispose to HCT-related morbidity and mortality. In this review, we summarize current knowledge on the cellular composition of the human BM niche after HCT. We describe how pre-HCT conditioning affects the cell types in the niche, including endothelial cells, mesenchymal stromal cells, osteoblasts, adipocytes, and neurons. Finally, we discuss therapeutic strategies to prevent or repair conditioning-induced niche damage, which may promote hematopoietic recovery and improve HCT outcome.
The current use of glaucoma virtual clinics in Europe
Authors: Azzopardi Matthew , Prokosch-Willing Verena , Michelessi Manuele , Fea Antonio Maria , Oddone Francesco , Mercieca Karl 
Published: June 2022

Abstract
Objectives
To assess and describe current utilisation, characteristics and perspectives on virtual glaucoma clinics (VGCs) amongst European glaucoma specialists.

Methods
Cross-sectional, anonymized, online questionnaire distributed to all European Glaucoma Society-registered specialists. Questions were stratified into five domains: Demographics, Questions about VGC use, Questions for non-VGC users, COVID-19 effects, and VGC advantages/disadvantages.

Results
30% of 169 participants currently use VGCs, with 53% based in the United Kingdom. Of those using VGCs, 85% reported higher patient acceptance compared to traditional care. The commonest virtual model was asynchronous remote monitoring (54%). Nurses (49%) and ophthalmic technicians (46%) were mostly responsible for data collection, with two-thirds using a mixture of professionals. Consultant ophthalmologists were the main decision-makers in 51% of VGCs. Preferred cohorts were: ocular hypertension (85%), glaucoma suspects (80%), early/moderate glaucoma in worse eye (68%), stable glaucoma irrespective of treatment (59%) and stable glaucoma on monotherapy (51%). Commonest investigations were: IOP (90%), BCVA (88%), visual field testing (85%) and OCT (78%), with 33 different combinations. Reasons for face-to-face referral included: visual field progression (80%), ‘above-target’ IOP (63%), and OCT progression (51%). Reasons for not using VGCs included: lack of experience (47%), adequate systems in place (42%), no appropriate staff (34%) and insufficient time/money (34%). 55% of non-VGC users are interested in their use with 38% currently considering future implementation. 83% stated VGC consultations have increased during the COVID-19 pandemic; 86% of all participants felt that the pandemic has highlighted the importance of VGCs.

Conclusions
A significant proportion of European glaucoma units are currently using VGCs, while others are considering implementation. Financial reimbursement and consensus guidelines are potentially crucial steps in VGC uptake.
Transition-metal-free synthesis of pyrimidines from lignin β-O-4 segments via a one-pot multi-component reaction
Authors: Zhang Bo , Guo Tenglong , Li Zhewei , Kühn Fritz E. , Lei Ming , Zhao Zongbao K. , Xiao Jianliang , Zhang Jian , Xu Dezhu , Zhang Tao , Li Changzhi 
Published: June 2022

AbstractHeteroatom-participated lignin depolymerization for heterocyclic aromatic compounds production is of great importance to expanding the product portfolio and meeting value-added biorefinery demand, but it is also particularly challenging. In this work, the synthesis of pyrimidines from lignin β-O-4 model compounds, the most abundant segment in lignin, mediated by NaOH through a one-pot multi-component cascade reaction is reported. Mechanism study suggests that the transformation starts by NaOH-induced deprotonation of Cα-H bond in β-O-4 model compounds, and involves highly coupled sequential cleavage of C-O bonds, alcohol dehydrogenation, aldol condensation, and dehydrogenative aromatization. This strategy features transition-metal free catalysis, a sustainable universal approach, no need of external oxidant/reductant, and an efficient one-pot process, thus providing an unprecedented opportunity for N-containing aromatic heterocyclic compounds synthesis from biorenewable feedstock. With this protocol, an important marine alkaloid meridianin derivative can be synthesized, emphasizing the application feasibility in pharmaceutical synthesis.
Photoredox catalytic radical fluorosulfonylation of olefins enabled by a bench-stable redox-active fluorosulfonyl radical precursor
Authors: Wang Peng , Zhang Honghai , Nie Xingliang , Xu Tianxiao , Liao Saihu 
Published: June 2022

AbstractSulfonyl fluorides have attracted considerable and growing research interests from various disciplines, which raises a high demand for novel and effective methods to access this class of compounds. Radical flurosulfonylation is recently emerging as a promising approach for the synthesis of sulfonyl fluorides. However, the scope of applicable substrate and reaction types are severely restricted by limited known radical reagents. Here, we introduce a solid state, redox-active type of fluorosulfonyl radical reagents, 1-fluorosulfonyl 2-aryl benzoimidazolium triflate (FABI) salts, which enable the radical fluorosulfonylation of olefins under photoredox conditions. In comparison with the known radical precursor, gaseous FSO2Cl, FABI salts are bench-stable, easy to handle, affording high yields in the radical fluorosulfonylation of olefins with before challenging substrates. The advantage of FABIs is further demonstrated in the development of an alkoxyl-fluorosulfonyl difunctionalization reaction of olefins, which forges a facile access to useful β-alkoxyl sulfonyl fluorides and related compounds, and would thus benefit the related study in the context of chemical biology and drug discovery in the future.
Hodge theory-based biomolecular data analysis
Authors: Wei Ronald Koh Joon , Wee Junjie , Laurent Valerie Evangelin , Xia Kelin 
Published: June 2022

AbstractHodge theory reveals the deep intrinsic relations of differential forms and provides a bridge between differential geometry, algebraic topology, and functional analysis. Here we use Hodge Laplacian and Hodge decomposition models to analyze biomolecular structures. Different from traditional graph-based methods, biomolecular structures are represented as simplicial complexes, which can be viewed as a generalization of graph models to their higher-dimensional counterparts. Hodge Laplacian matrices at different dimensions can be generated from the simplicial complex. The spectral information of these matrices can be used to study intrinsic topological information of biomolecular structures. Essentially, the number (or multiplicity) of k-th dimensional zero eigenvalues is equivalent to the k-th Betti number, i.e., the number of k-th dimensional homology groups. The associated eigenvectors indicate the homological generators, i.e., circles or holes within the molecular-based simplicial complex. Furthermore, Hodge decomposition-based HodgeRank model is used to characterize the folding or compactness of the molecular structures, in particular, the topological associated domain (TAD) in high-throughput chromosome conformation capture (Hi-C) data. Mathematically, molecular structures are represented in simplicial complexes with certain edge flows. The HodgeRank-based average/total inconsistency (AI/TI) is used for the quantitative measurements of the folding or compactness of TADs. This is the first quantitative measurement for TAD regions, as far as we know.
Effects of short chain fructo-oligosaccharides on selected skin bacteria
Authors: Le Bourgot Cindy , Meunier Claire , Gaio Elisa , Murat Vincent , Micheletto Marta , Tedesco Erik , Benetti Federico 
Published: June 2022

AbstractThe human skin microbiota plays a key role in the maintenance of healthy skin, ensuring protection and biological barrier by competing with pathogens and by closely communicating with the immune system. The development of approaches which preserve or restore the skin microbiota represents a novel target for skincare applications. Prebiotics could be applied to balance almost any microbial community to achieve advantageous effects. However, information about their effectiveness as skin microbiota modulators is limited. The objective of the current study was to evaluate the effects of short chain fructo-oligosaccharides (scFOS) from sugar beet (DP 3–5), well-recognised prebiotics, on some representative bacterial strains of the skin microbiota. We measured the growth and competitive activity of these specific bacteria for the use of scFOS as energy source in minimal medium and in a reconstructed human epithelium (RHE) in vitro model. In minimal growth medium, scFOS promoted and sustained the growth of Staphylococcus epidermidis up to 24 h, considered a beneficial skin commensal bacterium, while inhibiting both Cutibacterium acnes and Staphylococcus aureus growth, regarded as opportunistic pathogens. S. epidermidis showed the highest colonization potential and 1% scFOS was effective in shifting the competition in favour of S. epidermidis with respect to C. acnes in the RHE model. This latter effect was observed following 24 h of exposure, suggesting a long-term effect of scFOS in a highly skin dynamic environment. Therefore, scFOS could be effectively implemented in skincare formulations for recovering skin microbiota homeostasis.
Magnetostructural coupling in RFeO3 (R = Nd, Tb, Eu and Gd)
Authors: Vilarinho R. , Weber M. C. , Guennou M. , Miranda A. C. , Dias C. , Tavares P. , Kreisel J. , Almeida A. , Moreira J. Agostinho 
Published: June 2022

AbstractWe investigate the interplay of magnetization and lattice vibrations in rare-earth orthoferrites RFeO3, with a specific focus on non-symmetry-breaking anomalies. To do so, we study the magnetization, magnon excitations and lattice dynamics as a function of temperature in NdFeO3, TbFeO3, EuFeO3 and GdFeO3. The magnetization shows distinct temperature anomalous behavior for all investigated rare-earth orthoferrites, even in the compounds with no phase transitions occurring at those temperatures. Through spin–phonon coupling, these magnetic changes are mirrored by the FeO6 rotation mode for all the studied RFeO3, revealing a common magnetostructural effect associated with the octahedra rotations. The R3+ oscillation modes evidence a Fe3+/R3+ spins cross-talk for the NdFeO3 and TbFeO3 cases. Our work sheds light into the common magnetostructural coupling in rare-earth orthoferrites, and the important role of magnetic anisotropy and spin–orbit coupling strength of the R–Fe interactions on the spin-reorientation transition at high temperatures.