bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flares and rotation of M dwarfs with habitable zones accessible to TESS planet detections
Authors: Stelzer B. , Bogner M. , Magaudda E. , Raetz St. 
Published: June 2022

Context. More than 4000 exoplanets have been discovered to date, providing the search for a place capable of hosting life with a large number of targets. With the Transiting Exoplanet Survey Satellite (TESS) having completed its primary mission in July 2020, the number of planets confirmed by follow-up observations is growing further. Crucial for planetary habitability is not only a suitable distance of the planet to its host star, but also the star’s properties. Stellar magnetic activity, and especially flare events, expose planets to a high photon flux and potentially erode their atmospheres. Here especially the poorly constrained high-energy UV and X-ray domain is relevant.
Aims. We characterize the magnetic activity of M dwarfs to provide the planet community with information on the energy input from the star; in particular, in addition to the frequency of optical flares directly observed with TESS, we aim at estimating the corresponding X-ray flare frequencies, making use of the small pool of known events observed simultaneously in both wavebands.
Methods. We identified 112 M dwarfs with a TESS magnitude ≤11.5 for which TESS can probe the full habitable zone for transits. These 112 stars have 1276 two-minute cadence TESS LCs from the primary mission, which we searched for rotational modulation and flares. We study the link between rotation and flares and between flare properties, for example the flare amplitude-duration relation and cumulative flare energy frequency distributions (FFDs). Assuming that each optical flare is associated with a flare in the X-ray band, and making use of published simultaneous Kepler/K2 and XMM-Newton flare studies, we estimate the X-ray energy released by our detected TESS flare events. Our calibration also involves the relation between flare energies in the TESS and K2 bands.
Results. We detected more than 2500 optical flare events on a fraction of about 32% of our targets and found reliable rotation periods only for 12 stars, which is a fraction of about 11%. For these 12 targets, we present cumulative FFDs and FFD power law fits. We construct FFDs in the X-ray band by calibrating optical flare energies to the X-rays. In the absence of directly observed X-ray FFDs for main-sequence stars, our predictions can serve for estimates of the high-energy input to the planet of a typical fast-rotating early- or mid-M dwarf.
Stroke Mimics – Glioblastoma Presenting with Hemorrhage after Thrombolysis: Case Report
Authors: Gago Guilherme , Reis Marcelo Martins dos , Ferreira Marcelo Paglioli , Vial Antonio Delacy Martini , Worm Paulo Valdeci 
Published: June 2022

Abstract
Background Stroke is a clinical syndrome characterized by a sudden-onset neurological deficit of vascular cause. Stroke-like clinical symptoms that are later found to have nonvascular disorders have been termed stroke mimics (MIM), and their incidence ranges from 1.3 to 25% in patients not treated with thrombolytic therapy. Eventually, intravenous thrombolysis of MIM may occur.
Case Description We describe a 74-year-old woman with abrupt global aphasia who received thrombolytic therapy after the presumed diagnosis of acute ischemic stroke. She gradually improved despite the finding of an asymptomatic left temporal hematoma on the computed tomography (CT) scan. Two months later, she presented with a new focal neurological deficit and was diagnosed with a glioblastoma in the topography of the previous bleeding.
Conclusion This case highlights the rare occurrence of hemorrhage after thrombolysis in patients with MIM.
Avoidance Reduction Therapy for School-Age Children Who Stutter
Authors: Sisskin Vivian , Goldstein Benjamin 
Published: June 2022

AbstractAvoidance Reduction Therapy for Stuttering (ARTS) is a behavioral therapy for children and adults that incorporates speech therapy and counseling to reduce learned physical and socioemotional struggle that constitute the problem for the stutterer.a While stuttering is a neurodevelopmental difference, efforts to mask a stigmatized identity can contribute to avoidance, shame, and fear of speaking. This article provides theoretical foundations for therapy principles, describes the processes of self-acceptance and change, and outlines therapy goals and activities using child-friendly explanations and case study vignettes.
The Cost Analysis of a 7-Year Cross-Section of Patients with Epilepsy in a Single-Center Child Neurology Outpatient Clinic: A Descriptive Retrospective Analysis
Authors: Yilmaz Arzu 
Published: June 2022

AbstractThe cost analysis of the 7-year cross-section of the patients in pediatric neurology outpatient clinic including patients with foreign nationality was investigated retrospectively. Between January 10, 2013 and January 10, 2020, the total number of applicants, the nationalities of the patients, and the hospital cost were analyzed. Of 3,338 patients, aged between 0 and 20 years with mean age of 8.7 years at admission to the child neurology had received 17,476 clinical examinations. Of these, 51.6% were male and 93.5% cases were Turkish patients (n = 3,122), with 6.5% foreign nationals (n = 216). There was no difference in terms of gender between nationalities (p > 0.05). The total cost of cases with epilepsy was 1,312,427.73 Turkish Lira (TRY) and 6.2% account belonged to foreign nationals, mostly from Iraq (3.6%, n = 119) and Syria (2.4%, n = 80). The highest proportion of foreigner admissions due to epilepsy was in 2018 (11.1%). Mean average of health expenditures for foreign nationals diagnosed with epilepsy was 6.2% with the highest expenditure in 2019 (27.750,06 TRY). The proportion of admissions for epilepsy was 27.6% (17,476/63,173) among all neurological admissions. The proportion of Turkish patients was 25.6% (6,181/63,173), and 3.8% (1,295/3,398) accounted for foreigners' admissions. The proportion of total epilepsy costs compared with the total neurological admissions was 30% (1.312.427,73 TRY/4.347.592,80 TRY) and among them, the expenditure proportion for epilepsy in Turkish patients compared with that of total foreigner admissions was 3.9% (80.416,44 TRY/201.490,515 TRY). Expenditures for evaluating of epileptic children with foreign nationality cover an average of 6.5% of the entire section of the health expenditures made for patients with the diagnosis of epilepsy in the pediatric neurology outpatient clinic over the 7-year period. Epilepsy accounts for 30% admissions among all neurological admissions with 3.9% belonging to foreign national admissions.
Depiction of Cerebral Aneurysm Wall by Computational Fluid Dynamics (CFD) and Preoperative Illustration
Authors: Tanaka Riki , Liew Boon Seng , Yamada Yasuhiro , Sasaki Kento , Miyatani Kyosuke , Komatsu Fuminari , Kawase Tsukasa , Kato Yoko , Hirose Yuichi 
Published: June 2022

Abstract
Introduction Preoperative illustration is a part of an important exercise to study the configuration, direction, and presence of any perforations, and is the weakest point in the wall of the cerebral aneurysm. The same illustration is used to study the surrounding brain structures to decide the best and safe surgical approach prior to any surgical procedure. With the evolution of the aneurysm wall study and study of flow dynamic within the involved artery and its aneurysm wall using computational fluid dynamics (CFD), a better surgical plan can be formulated to improve the flow dynamics. As one of the clinical applications of CFD, we propose a study using a composite image that combines preoperative illustration and CFD, which is traditionally widely used in neurosurgery.
Methods and Materials We study the use of illustrations of the unruptured cerebral aneurysm of internal carotid-posterior communicating (ICPC) artery and anterior communicating artery (AcomA) treated at our hospital. The combinations of both preoperative illustrations and CFD images by using “ipad Pro” were used.
Result and Conclusion Medical illustration in the preoperative study of unruptured cerebral aneurysm with combinations of CFD and surrounding brain structures is helpful to decide the surgical approaches and successful surgical treatments.
A Review of Direct Endobiliary Techniques for the Management of Biliary Conditions
Authors: Garg Tushar , Singh Harjit , Weiss Clifford R. 
Published: June 2022

AbstractA majority of patients with cholangiocarcinoma and malignant biliary obstruction cannot undergo surgery for treatment as they present late in the disease course. It is crucial to relieve biliary obstruction in these conditions, for which metallic stents are commonly used. However, these stents have a high rate of occlusion due to the ingrowth of malignant tissue. In this review, we will discuss the use of direct endobiliary therapies that can be used either independently or in combination with metallic stents.
At the Eye of the Hurricane! Perioperative Management of an Unoptimized Metastatic Pheochromocytoma Presenting for Emergency Neurosurgery
Authors: Suresh Sapna , Hrishi Ajay Prasad , Divakar Ganesh , Sethuraman Manikandan 
Published: June 2022

Abstract
Metastatic pheochromocytoma (PCC) is a rare entity arising from extra-adrenal tissue. We report the perioperative management of a young woman presenting with metastatic PCC to the vertebral body resulting in vertebral collapse and spinal cord compression necessitating emergency surgery. There are no reports of anesthetic management of a patient with unoptimized metastatic PCC presenting for emergency neurosurgery under general anesthesia. Our anesthetic goals were to maintain a deep anesthetic plane with stable hemodynamics, facilitate intraoperative neuromonitoring, manage catecholamine surges during anesthetic induction, tumor resection, and manage perioperative massive blood loss. The successful perioperative management of metastatic PCC has become possible with the vast armamentarium of anesthetic drugs and intraoperative advanced monitoring techniques. In addition, our role in understanding the pathophysiology and course of the disease is essential to ensure low morbidity and mortality of such cases in their most vulnerable perioperative period.
The History of Plastic Surgery in Israel
Authors: Wolf Yoram , Hagen Binyamina Rosenberg , Yafe Batya , Golan Jacob , Shulman Ori , Har-Shai Yaron , Neuman Rami 
Published: June 2022

AbstractToday, plastic surgery is a well-known profession with highly respected surgeons from institutions all over the world. Over the last several decades numerous clinical and technological advances have been made, thanks to the dedication and hard work of these outstanding professionals; however, things were not always this way. At the turn of the 20th century, Israel had yet to be introduced to the field of plastic surgery. However, this all changed with the War of Independence. Humanitarian aid by the prominent South African surgeon, Jack Penn, laid the foundation for the founding fathers of plastic surgery in Israel to establish a strong legacy of producing world-renowned surgeons and innovators. Through this paper, we hope to provide a brief overview of the history of plastic surgery in Israel and what transpired to give us the state of surgical practice we have today.
The reflexive cycle
Authors: Kiss Katalin É. , Mus Nikolett 
Published: June 2022

AbstractStarting from a morphosyntactic puzzle of the Ugric and Samoyedic languages of the Uralic family (possessive agreement suffixes functioning as accusative allomorphs on pronominal objects), this paper identifies a pronoun cycle which leads from reflexives via intensifiers and via referentially independent intensive pronouns to neutral pronouns. In Tundra Nenets, evidence of three rounds of reflexive renewal is also pointed out, with the three sets of pronouns frozen at different stages of the cycle. The analysis has implications for debated issues of language change. It is shown that elements participating in cyclic changes not only suffer feature loss but also incorporate features. Based on the recurring cycle in Tundra Nenets, it is argued that the cyclicity of linguistic changes implies a notion of unidirectionality that also leaves room for unpredictable outcomes.
Evidentiality in Finnish
Authors: Kaiser Elsi 
Published: June 2022

AbstractEvidentiality conveys information about the nature – and reliability – of the information source. This paper investigates the Finnish reportative evidential (hearsay particle)kuulemmaand the dubitative particlemuka(‘supposedly, allegedly, as if’). I propose a unifying analysis of two seemingly divergent uses ofmuka, and show how they contrast withkuulemma. My analysis builds on and extends recent work on reportatives regarding the distinction between the Animator (the speaker who utters the sentence) and the Principal (the person whose commitments are being expressed). Furthermore, I suggest that the dubitativemukamay point to the existence of non-assertive discourse moves and has implications for our understanding of the discourse role of ‘Principal.’ This work also informs typological work on evidentials and related expressions by providing a systematic investigation of reportative and dubitative markers in a non-Indo-European language.
Development of the use of discourse markers across different fluency levels of CEFR
Authors: Huang Lan-fen , Lin Yen-liang , Gráf Tomáš 
Published: June 2022

AbstractFluent L2 English speakers frequently use discourse markers (DMs) as a speech management strategy, but research has largely ignored how this develops across different proficiency levels and how it is related to immersive experiences. This study examines the developmental patterns of three DMs –well,you knowandlike – in the speech of learners at A2-C1 in CEFR with and without immersive experiences in target language environments. The fluency-rated LINDSEI corpus (173 learners) and a parallel native corpus (50 speakers) provided approximately 350,000 tokens and 3,395 instances of the analyzed DMs. Overall, DM frequency (especially withwellandyou know) among C1 speakers increases with rising fluency levels up to almost native-like levels. Immersive experience correlates positively with overall and individual DM frequency (except forlike). As the skillful use of DMs results in more fluent speech production, the didactic implications for L2 instructors should be developed.
3-aminoquinoline: a turn-on fluorescent probe for preferential solvation in binary solvent mixtures
Authors: Das Sharmistha , Das Shirsendu , Singh Avinash Kumar , Datta Anindya 
Published: June 2022

Abstract
3-Aminoquinoline (3AQ) has been used as a fluorescent probe for preferential solvation in hexane-ethanol solvent mixtures. Results of the present experiment have been put into context by comparison with prior observations with 5-aminoquinoline (5AQ) as the probe. 3AQ exhibits a relatively small change of dipole moment (Δμ = 2.2 D) upon photoexcitation, compared to 5AQ (Δμ = 6.1D), which might appear to be a hindrance in the way of its use as a solvation probe. Indeed, the values of parameters like spectral shifts are smaller for the present experiment with 3AQ. At the smallest concentration of alcohol used, its local mole fraction around the probe is significantly lower than in the previous experiments with 5AQ. However, these apparent disadvantages are outweighed by the significant increase in fluorescence intensity and lifetime observed with increasing concentration of ethanol in the solvent mixture, as opposed to the drastic fluorescence quenching that occurs for 5AQ. This is a marked advantage in the use of 3AQ in studies like the present one. The local mole fraction of ethanol and preferential solvation index experienced by 3AQ are in line with those reported for 5AQ. The disadvantage of the smaller magnitude of Δμ persists in the time resolved fluorescence experiments, for solvent mixtures with very low ethanol content. Negligible wavelength dependence of fluorescence transients of 3AQ is observed for x

p
= 0.002,. However, this effect is outweighed at higher alcohol concentrations, for which nanosecond dynamics of preferential solvation is observed.
Corrosion and wear performances of hydroxyapatite and boron-containing TiO2 composite coatings on Ti6Al7Nb alloy
Authors: Vangolu Yenal , Kilic Savas 
Published: June 2022

Abstract
Plasma electrolytic oxidation coupled with hydrothermal treatment is a relatively new technique to form a hydroxyapatite/TiO2 layer on titanium alloys for biomedical applications. Hence the process allows achieving a bioactive and bactericidal surface by using electrolytes that contain ions (such as calcium-phosphorus and boron) necessary for desired properties. The coating properties are controllable by adjusting the parameters in the PEO process. In the present study, an electrolyte that contains both calcium, phosphorus, and boron ions was used to form a rough and porous oxide layer on Ti6Al7Nb which is known to be less toxic than the most widely used Ti alloy for biomedical applications, Ti6Al4V. A hydroxyapatite and boron-containing oxide layer was obtained after plasma electrolytic oxidation and hydrothermal treatment. Coatings were examined by XRD, XPS, SEM, contact angle measurement system, micro-hardness tester, wear tester, and corrosion measurement system. The results showed that the wear and the corrosion properties of all coated samples increased. Especially boron doping enhanced both the wear and corrosion resistance. Relatively the best corrosion resistance was achieved from CaP-B and the best wear resistance was from HA-B samples. The hardness values and mean surface roughness of all coated samples also increased while the average friction coefficients decreased. The hardness increased from 323 ± 5 HV0.1 to 1084 ± 16 HV0.1 where the coefficient of friction decreased from 0.5672 ± 0.01 to 0.4697 ± 0.03.
Investigation of the protection effect of ginger, tea tree and grapefruit essential oil extracts on mild steel in 0.5M H2SO4solution
Authors: Loto Roland Tolulope 
Published: June 2022

AbstractUtilization of plant extracts for the corrosion protection of metallic alloys has increased significantly in the last few years. Ginger (GII), tea tree (TT) and grapefruit (GP) essential oil extracts were evaluated for their corrosion protection effect on mild steel in 0.5 M H2SO4media by potentiodynamic polarization, weight loss analysis, open circuit potential measurement, optical microscopy and ATF-FTIR spectroscopy. Corrosion rate from weight loss and polarization at 0% extract concentration decreased from 63.33 mm y−1and 18.01 mm y−1to values between 0.31 mm y−1and 1.96 mm/y for weight loss, and 0.604 mm y−1and 0.161 mm/y for polarization at optimal extract concentration. Generally, the extracts performed effectively with inhibition efficiency above 95%. The extracts displayed mixed-type inhibition properties though with significant effect on the cathodic plot while the anodic plots indicate activation control mechanism. Corrosion inhibition of GII extract obeyed the Langmuir and Frumkin isotherm model while TT extract inhibition adhered to Langmuir, Frumkin, Frundlich and Temkin isotherms. GP extract inhibition obeyed the Langmuir isotherm only. Correlation coefficient of the isotherms were generally above 0.9. Adsorption of the extracts aligned with chemisorption adsorption from thermodynamic calculations. Open circuit potential plots in the presence of the extracts/acid solution generally depict significant electropositive shift compared to the plot in the absence of the extracts which was relatively electronegative. Potential variations were observed on the plots of the extracts due to miniature active passive transit characteristics at the extract-metal interphase. ATF-FTIR spectroscopic data shows the functional groups in TT extract molecules adsorbed onto the steel exterior compared to GII and GP extract molecules which depict surface coverage from analysis of the wavelength and transmittance data. Optical image of mild steel after corrosion depicts significantly degraded exterior with corrosion pits. However, in the presence of the extracts the steel morphology was well protected.
Noiseless linear amplification in quantum target detection using Gaussian states
Authors: Karsa Athena , Ghalaii Masoud , Pirandola Stefano 
Published: June 2022

Abstract
Quantum target detection aims to utilise quantum technologies to achieve performances in target detection not possible through purely classical means. Quantum illumination is an example of this, based on signal–idler entanglement, promising a potential 6 dB advantage in error exponent over its optimal classical counterpart. So far, receiver designs achieving this optimal reception remain elusive with many proposals based on Gaussian processes appearing unable to utilise quantum information contained within Gaussian state sources. This paper considers the employment of a noiseless linear amplifier at the detection stage of a quantum illumination-based quantum target detection protocol. Such a non-Gaussian amplifier offers a means of probabilistically amplifying an incoming signal without the addition of noise. Considering symmetric hypothesis testing, the quantum Chernoff bound is derived and limits on detection error probability is analysed for both the two-mode squeezed vacuum state and the coherent state classical benchmark. Our findings show that in such a scheme the potential quantum advantage is amplified even in regimes where quantum illumination alone offers no advantage, thereby extending its potential use. The same cannot be said for coherent states, whose performances are generally bounded by that without amplification.
3D bioprinted glioma models
Authors: Yigci Defne , Sarabi Misagh Rezapour , Ustun Merve , Atceken Nazente , Sokullu Emel , Bagci-Onder Tugba , Tasoglu Savas 
Published: June 2022

Abstract
Glioma is one of the most malignant types of cancer and most gliomas remain incurable. One of the hallmarks of glioma is its invasiveness. Furthermore, glioma cells tend to readily detach from the primary tumor and travel through the brain tissue, making complete tumor resection impossible in many cases. To expand the knowledge regarding the invasive behavior of glioma, evaluate drug resistance, and recapitulate the tumor microenvironment, various modeling strategies were proposed in the last decade, including three-dimensional (3D) biomimetic scaffold-free cultures, organ-on-chip microfluidics chips, and 3D bioprinting platforms, which allow for the investigation on patient-specific treatments. The emerging method of 3D bioprinting technology has introduced a time- and cost-efficient approach to create in vitro models that possess the structural and functional characteristics of human organs and tissues by spatially positioning cells and bioink. Here, we review emerging 3D bioprinted models developed for recapitulating the brain environment and glioma tumors, with the purpose of probing glioma cell invasion and gliomagenesis and discuss the potential use of 4D printing and machine learning applications in glioma modelling.
Mobility, environment and inequalities in the post-COVID city
Authors: Albalate Daniel , Bel Germà , Gragera Albert 
Published: June 2022

Abstract
The COVID-19 pandemic has brought about enormous disruption in mobility in cities. We review and analyse the evidence generated since the advent of the crisis, paying special attention to travel behaviour changes and how they are hampering the achievement of sustainability goals. Modal shifts to more individual modes of transport, with regained interest in car usage, combined with the financial distress of public transportation and raising inequalities, appear as the most challenging problems city planners face if travel preferences do not revert shortly. We discuss policies and measures that could be implemented so that these risks are addressed and lessened.