bluuebunny/crossref_metadata_2025_split huggingface dataset:
Co-creating physical activity interventions: Findings from a multiple case study using mixed methods
Authors: Popp Johanna , Grüne Eva , Carl Johannes , Semrau Jana , Pfeifer Klaus 
Published: September 2022

IntroductionIn health and physical activity promotion, there is growing interest in co-creation approaches that involve researchers and non-academic stakeholders in developing new interventions. Previous research has shown the promising results of cooperative planning as a co-creation approach in building new capacities and implementing physical activity-promoting interventions in nursing care and automotive mechatronics. However, it remains unclear whether (1) cooperative planning for physical activity promotion can be successfully transferred to other settings in the nursing care and automotive mechatronic sectors and (2) what key factors influence its success or failure.MethodsWe conducted a multiple case study in three settings in the nursing care and automotive mechatronics sectors. Following a mixed methods approach, we collected, analyzed, and triangulated data from documents (n= 17), questionnaires (n= 66), and interviews (n= 6). Quantitative data were analyzed descriptively and through using nonparametric analyses of variance; qualitative data were analyzed using qualitative content analysis by extraction.ResultsThe transfer of cooperative planning to new settings was realized, though the impact varied by setting. While the interventions were developed and implemented in nursing care settings, interventions were developed but not implemented in the automotive mechatronics setting. In this context, intervention implementation was influenced by 11 key factors:champion, commitment, embedment, empowerment, engagement, health-promoting leadership, ownership, relevance, resources, responsibility, andstrategic planning. Furthermore, the transfer of cooperative planning was influenced by different activity characteristics, namelyelaboration &amp; reconsideration, group composition, number of meetings, participation, period, prioritization, andresearchers' input &amp; support.DiscussionThe present article contributes to a better understanding of a co-creation approach utilized for physical activity promotion and provides new insights into (1) the transferability of cooperative planning and (2) the associated key factors influencing intervention implementation. The success of cooperative planning varied by setting and was influenced by several activity characteristics and key factors, some of which showed complex relationships. This raises the question of whether some settings might benefit more from a co-creation approach than others. Therefore, future co-creation initiatives should carefully consider the specific characteristics of a setting to select and apply the most appropriate approach.
Cost-effectiveness of ensartinib, crizotinib, ceritinib, alectinib, brigatinib and lorlatinib in patients with anaplastic lymphoma kinase-positive non-small cell lung cancer in China
Authors: Luo Xia , Zhou Zhen , Zeng Xiaohui , Peng Liubao , Liu Qiao 
Published: September 2022

ObjectiveSix anaplastic lymphoma kinase-tyrosine kinase inhibitors (ALK-TKIs), including one domestic (ensartinib) and five imported ALK-TKIs (crizotinib, ceritinib, alectinib, brigatinib, and lorlatinib), have been recommended as first-line treatments for advanced ALK-positive NSCLC in China. This study sought to examine the cost-effectiveness of these six novel therapies in Chinese patients.Material and methodsWe constructed a Markov model to compare the cost-effectiveness of the six ALK-TKIs as a first-line treatment for patients with advanced ALK-positive NSCLC from the perspective of the Chinese healthcare system. Transition probabilities were estimated by synthesizing data from the PROFILE 1,029 trial and a network meta-analysis. Health state utilities and costs were sourced from published literature, publicly available national databases, and local general hospitals. The robustness of model was assessed via deterministic sensitivity analyses and probabilistic sensitivity analyses.ResultsCompared with crizotinib, ensartinib achieved additional 0.12 quality-adjusted life-year (QALY) with marginal costs of $3,249, resulting in an incremental cost-effectiveness ratio (ICER) of $27,553/ QALY. When compared with ceritinib and brigatinib, ensartinib achieved additional 0.06 and 0.03 QALYs with substantially reduced costs. When compared with lorlatinib and alectinib, ensartinib was associated with a lower QALY and decreased total costs; the ICERs for lorlatinib and alectinib were $934,101/ QALY and $164,888/ QALY, respectively.ConclusionFor Chinese patients with advanced ALK-positive NSCLC, ensartinib was a cost-effective option compared with crizotinib, and was a dominant alternative to ceritinib and brigatinib. Although lorlatinib and alectinib were associated with prolonged survival compared with ensartinib, they were less cost-effective than ensartinib due to the overwhelming total costs.
The tibial insertion of the hamstring can be considered to be preserved during anterior cruciate ligament reconstruction
Authors: Fang Kaibin , Dai Zhangsheng , Lin Xiaocong 
Published: September 2022

BackgroundHamstring as a graft was very common in anterior cruciate ligament reconstruction surgery. Usually the hamstring muscles needed to be taken out and then woven to be used.AimIn order to investigate whether it was beneficial for patients to preserve the transpedicular insertion of hamstring when using the hamstring as a graft for anterior cruciate ligament reconstruction.MethodsThis was a retrospective study. Patients with anterior cruciate ligament injury who underwent surgery in a large hospital from January 2015 to May 2021 were included in the study. These patients underwent anterior cruciate ligament reconstruction assisted by arthroscopic. Autologous hamstring muscles were used as grafts. The tibial insertion of the hamstring were preserved during the operation were included in the observation group. The remaining patients were included in the control group. The knee joint function and operation of the two groups were compared.ResultsA total of 97 patients were included in the study. There was no statistical difference between the two groups in general data including gender, age and surgical side. All the patients’ operations were successfully completed there was no significant difference in the operation time between the two groups. All patients were followed up for at least 1 year. No patients had complications such as wound infection and graft failure at the last follow-up. There was no significant difference between the two groups in Lysholm score and IKDC score before operation. Similarly, there was no significant difference between the two groups in Lysholm score and IKDC score 3 months after operation. However, the Lysholm score and IKDC score of the two groups 1 year after operation were statistically different, and the patients in the observation group had higher Lysholm score and IKDC score. After comparing the MRI images of the knee of the two groups 3 months after operation through the MRI evaluation system, compared with the patients in the control group, the patients in the observation group have higher scores, and the difference was statistically significant.ConclusionIn the knee arthroscopic assisted anterior cruciate ligament reconstruction using the hamstring as a graft, the tibial insertion of the hamstring can be preserved, which can make the patient have better function after the operation. This kind of operation leads to the increase of operation time and operation risk.
Antibiotic Resistance Patterns in Pediatric Urinary Tract Infections: A Comparison Between 2013-2015 and 2019-2021
Authors: AKYOL ONDER Esra Nagehan , ERTAN Pelin 
Published: September 2022

Objective: Urinary tract infections (UTIs) are one of the most common infections in children. The aim of this study was to assess and compare the etiology and antibiotic susceptibility results of urine cultures obtained between 2013-2015 and 2019-2021 and evaluate local epidemiologic differences over years.
Materials and Methods: A total of 1,000 samples with positive urine cultures (500 cultures each for the 2013-2015 and 2019-2021 periods) and antibiogram results were included in this study.
Results: The most grown uropathogens were Escherichia coli and Klebsiella spp. in both two periods. E. coli and Klebsiella spp. showed high resistance to ampicillin, amoxicillin, trimethoprim-sulfamethoxazole, cefuroxime, and ceftriaxone. The resistance rates of E. coli to ampicillin, amoxicillin and trimethoprim-sulfamethoxazole were reported as 65%, 46%, and 45%, respectively and significantly increased in 2019-2021 compared to 2013-2015 (p
Diyabetik Makula Ödeminde İntravitreal Ranibizumab Enjeksiyonunun Farklı Optik Koherens Tomografi Morfolojileri Üzerindeki Etkisi
Authors: ALTINIŞIK Muhammed , BAYRAKTAR Havvanur , KOYTAK Arif 
Published: September 2022

Giriş ve Amaç: Spektral-domain optik koherens tomografi (SD-OKT) ile belirlenen farklı paternlerdeki diyabetik maküla ödemi (DMÖ) olgularında intravitreal ranibizumab (İVR) enjeksiyonunun erken dönem etkinliğini karşılaştırmak.
Gereç ve Yöntemler: Tek doz İVR uygulanmış nonproliferatif diyabetik retinopatiye sekonder DMÖ olguları retrospektif olarak analiz edildi. Klinik anlamlı santral DMÖ’sü olan ve santral fovea kalınlığı (SFK)≥250 µm olan gözler çalışmaya dahil edildi. Olgular SD-OKT morfolojisine göre; süngerimsi diffüz retina kalınlaşması (DRK), kistoid maküla ödemi (KMÖ) ve seröz retina dekolmanı (SRD) gruplarına ayrıldı. Gruplar enjeksiyon öncesi ve enjeksiyon sonrası birinci ay kontrollerinde, en iyi düzeltilmiş görme keskinliği (EİDGK), SFK ve total maküla volümü (TMV) değişimi açısından karşılaştırıldı. SFK değişimi üzerindeki başlangıç SFK değerlerinin etkisini dışlamak için ANCOVA analizi ve gruplar arasında randomizasyon yapılarak alt analizler yapıldı.
Bulgular: Çalışmaya 101 olgu (44 DRK, 40 KMÖ ve 17 SRD) dahil edildi. Gruplar yaş ve cinsiyet dağılımı açısından benzerdi (p>0,05). Başlangıç EİDGK ve TMV değerleri arasında anlamlı fark yok iken (p>0,05), başlangıç SFK değerleri büyükten küçüğe doğru sırası ile SRD, KMÖ ve DRK şeklinde sıralandı (p
EVALUATION OF TREATMENT VOLUME DETERMINATION FOR ANAPLASTIC OLIGODENDROGLIOMAS BASED ON MULTIMODALITY IMAGING: AN ORIGINAL ARTICLE
Authors: AKIN Mustafa , DUZOVA Mursel 
Published: September 2022

Objective: Utility of radiation therapy (RT) has been well established for management of World Health Organization (WHO) grade 3 anaplastic oligodendroglioma. Nevertheless, optimal target definition for radiotherapeutic management of WHO grade 3 anaplastic oligodendroglioma requires elucidation. Within this context, treatment volume determination for WHO grade anaplastic oligodendroglioma based on multimodality imaging is assessed in this original research article.
Materials and methods: Treatment volume determination for RT by incorporation of MRI or by CT-simulation images only was comparatively assessed for patients receiving RT for WHO grade 3 anaplastic oligodendroglioma in this original research article.
Results: VersaHD (Elekta, UK) Linear Accelerator (LINAC) was used for treatment with 6 MV photons. IGRT techniques were utilized for treatment verification. Ground truth target volume was used as the reference for actual treatment and for comparison purposes, and it was determined after meticulous evaluation on an individual basis. Primary outcome measure of the study was comparative assessment of treatment volume determination by either CT-only imaging and by CT-MR fusion based imaging. This study revealed that the ground truth target volume was identical with treatment volume definition by CT-MR fusion based imaging.
Conclusion: This study reveals improved treatment volume determination for WHO grade 3 anaplastic oligodendrogliomas by incorporation of MRI in the treatment planning procedure. Clearly, further studies are warranted to shed light on this issue.
Comparison of Early Outcomes of Laparoscopic Floppy Nissen Fundoplication and Laparoscopic Toupet Fundoplication in the Treatment of Type III and IV Hiatal Hernia
Authors: TAYAR Serkan , KALAYCI Tolga 
Published: September 2022

Objective: This study aims to compare the laparoscopic Floppy Nissen fundoplication technique (LFNFT) and the laparoscopic Toupet fundoplication technique (LTFT) used in treating Type III and IV hiatal hernias (HHs).
Materials and Methods: This retrospective analysis was conducted after ethical approval. Patients who underwent Type III and IV hiatal hernia surgery were searched between January 2020 and May 2022. Patients who underwent LFNFT and LTFT for hiatal hernia repair were selected. Patients under 18 and patients who were followed up in our clinic after surgery were excluded from the study. The clinical and follow-up differences between the groups were evaluated statistically.
Results: Of the 38 patients who met the study criteria, 27 (71.1%) were female. The mean age of all patients was 41.39±14.03 years (21-77). 10 (26.3%) patients had Type 3 HH, and the remaining patients (73.7%) had Type 4 HH. LFNFT was performed on 27 (71.1%) patients, and LTFT on 11 (28.9%). Complications developed in 14 (36.8%) patients in the postoperative follow-up, and the most common difficulty was gas bloating, with a rate of 13.1%. In comparing the groups, LTFT was preferred in the male patients (p=0.005) and younger patients (p
Assessment of the functional state and level of physical fitness of people with immunodeficiency virus with different levels of T-lymphocytes in the practice of a physical therapist
Authors: Orfin Andrii , Mazepa Maria 
Published: September 2022

Purpose: to assess the functional state of patients with human immunodeficiency virus with different levels of T-lymphocytes for use in the practice of physical therapy.
Materials and methods. We examined 24 patients with human immunodeficiency virus at the stage of acquired immunodeficiency syndrome at the outpatient stage of treatment. The patients were divided into 2 groups. Group 1 included 11 patients with CD4+ T-lymphocyte levels <100 cells ml-1, and group 2 included 13 patients with CD4+ T-lymphocyte levels above 150 cells ml-1 (р<0.01). The clinical and anamnestic data, the main anthropometric parameters and physiological indices, the results of carpal dynamometry, the 6-minute walk test, characterizing the functional state of people living with the human immunodeficiency virus, were studied. The results of immunological, virological and biochemical parameters were also studied.
Results. Anthropometric indicators: Group 1 – body mass index 48.9±7.4 kg m2-1, waist to hip ratio ratio 0.92±0.17 cm, leg circumference 16.6±0.8 cm; Group 2 – body mass index 23.1±2.8 kg m2 -1, waist to hip ratio ratio 1.14±0.11 cm, leg circumference 15.9±1.4 cm (р>0.05 ). Indicators of physiological indices: Reed - group 1 - 17.3±7.2%, group 2 - 18.3±11.8% (p>0.05); Hobbes - group I 70.9 ± 5.5%, group 2 - 93.6 ± 11.8% (p<0.05), Kerdo - group 1 was 26.6 ± 14.2%, group 2 - 10 .8 ± 14.7% (р<0.05). Index of functional changes group 2 - 2.44±0.2 points, group 2 - 2.59±0.3 points (p>0.05). Dynamometry indicators - group I - 17.5 ± 6.8 kg, group 2 - 28.1 ± 9.4 kg (р>0.05); strength index – group 1 35.3±-9.6%, group 2 40.5±10.4% (р>0.05); 6 min walk test in group 1 - 402.8±40.04 m, group 2 459.7±56.1 m (р<0.05). Indicators of biochemical studies were in reference values ??in patients of both groups.
Conclusions. There is a decrease in the functional state and the predominance of catabolic processes in people with human immunodeficiency virus with a significant deficiency of CD4+ T-lymphocytes.
Gambaran tingkat stress mahasiswa kebidanan tingkat III dalam mengahadapi ujian akhir program di sekolah tinggi ilmu kesehatan putra abadi langkat stabat
Authors: Supriatik Supriatik , Dewiwati Tri Suci 
Published: September 2022

Stres adalah munculnya reaksi psikologis yang membuat seseorang merasa tegang atau cemas yang disebabkan ketidak mampuan mengatasi atau meraih tuntutan atau keinginannya. Tujuan untuk mengetahui gambaran tingkat stress mahasiswa kebidanan tingkat III dalam mengahadapi Ujian Akhir Program di STIkes Pal Stabat Tahun 2014. Jenis penelitian ini adalah survei yang bersifat deskriptif dengan data primer yang bertujuan untuk mengetahui gambaran tingkat stress mahasiswa kebidanan tingkat III menghadapi Ujian UAP di STIKes Pal Stabat. Populasi dalam penelitian ini adalah seluruh mahasiswa kebidanan tingkat III yang berjumlah 91 orang dan pengambilan sampel menggunakan teknik total sampling. Hasil penelitian yang diperoleh Mahasiswa Kebidanan Tingkat III yang mengalami stress menghadapi ujian UAP di STIKes Pal Stabat terjadi pada kategori Tingkat Tinggi sebanyak 69 orang (75,8%) mengalami gejala fisik, gejala psikis yang disebabkan oleh beberapa faktor antara lain yaitu sulitnya proses bimbingan, banyaknya tugas kuliah dan tuntutan akademik yang harus diselesaikan sesuai denagn jadwal yang telah ditentukan oleh pendidikan. Diharapkan kepada seluruh mahasiswa untuk dapat mempersiapkan diri dalam menghadapi ujian UAP dimulai dari belajar dengan baik dan serius dari awal proses pembelajaran dan kepada para dosen untuk lebih memperhatikan cara belajar mahasiswa di pendidikan agar mahasiswa dapat dilakukan pembelajaran secara maksimal.
Reflecting Teacher’s Strategies for Teaching Speaking in Online Learning: A Case Study
Authors: Mardiani Ridha , Dirgantara Herrisyandhi 
Published: September 2022

Teaching Speaking during Pandemic COVID-19 has forced a female English teacher to conduct it in an online setting. This required the teacher to implement strategies to help the students learn optimally. She tried to shift her teaching strategies from her traditional classroom strategies to online teaching strategies. Using a case study as the method employed in this research, carrying out classroom observation, conducting teacher interviews, and writing teacher’s journals as the instruments to obtain the data. The teacher’s reflection was made based on a reflective teaching framework in which the teacher’s beliefs and practices are carefully analyzed to see the strategies employed by the teacher. The result shows that her belief in teaching speaking is to motivate and stimulate the students to speak some English words, sentences, or dialogues; drilling and role-playing added by online YouTube videos as her main techniques in teaching speaking. By writing her teaching journal, she expected to have some enhancement in her teaching, classroom management, and students’ responses. The researchers hope that the result of this research can be used as a reference by other researchers to cope with any challenges that occurred while teaching speaking in online learning.
Pembuatan 3D Model Disc Refiner dengan Reverse Engineering untuk Mendukung Sustitusi Impor
Authors: Eryantono Anugrah Erick , Virdhian Shinta , Cahyadi Deny , Oktavia Evi 
Published: September 2022

Indonesia is known as one of the largest pulp and paper manufacturers in the world. However, it still relies too heavily on technology from foreign countries. In relation to the Government’s policy to support import substitution, the use of domestic goods should be increased including in this sector. Therefore, the inverse of engineering design or reverse engineering technique should be implemented in an effort to manufacture the disc refiner in the local industry. This technique is a long process that started by identifying the existing product then choosing the suitable manufacturing method and finally generate the same product or even the enhanced version. This paper will present how to build the 3D model of the pulp disc refiner using 3D-scanner and CAD software as the essential step in reverse engineering technique. In addition, it will also provide the material composition of the disc refiner for the preparation to manufacture the improved product. The result of this research can be used as guidance for the local machinery manufacturers to strengthen their competitiveness, especially in manufacturing the machines for pulp and paper industries.
Keywords: 3D model, disc refiner, reverse engineering, manufacture, import substitution.
Pengaruh Pemberlakuan Kebijakan Asas Cabotage Terhadap Surplus Ekonomi Di Industri Pelayaran Indonesia
Authors: Delayori Farhan 
Published: September 2022

Indonesia merupakan negara kepulauan yang memiliki potensi besar dalam industri pelayaran. Implementasi kebijakan Asas Cabotage di Indonesia sejak tahun 2005 hingga saat ini kerap kali menjadi polemik dikalangan pemangku kebijakan. Hal tersebut dikarenakan adanya perbedaan pendapat dari para ahli atau studi empiris sebelumnya terkait dampak negatif dan positif implementasi kebijakan Asas Cabotage di perairan Indonesia ini. Asas Cabotage di Indonesia merupakan hak ekslusif yang diberikan kepada negara untuk bebas mengatur jalur transportasi, dalam hal ini transportasi laut. Pemerintah Indonesia menggunakan Asas Cabotage dengan cara memberlakukan aturan dimana hanya kapal berbendera Indonesia yang dapat mengangkut barang/penumpang di perairan laut Indonesia. Upaya pemerintah Indonesia ini untuk melindungi dan memberdayakan industri pelayaran di Indonesia. Dalam penelitian ini akan dilakukan analisis terkait struktur pasar akibat dari penerapan Asas Cabotage, setelah itu melakukan komparasi freight cost antara pelayaran lokal dengan asing, serta membuat simulasi berdasarkan tiga skenario yaitu penerapan penuh kebijakan Asas Cabotage, penerapan secara sebagian, dan tidak ada penerapan Asas Cabotage di perairan laut Indonesia. Hasilnya ialah kebijakan Asas Cabotage yang berupa pembatasan berpotensi membuat pasar menjadi tidak sempuna, berdasarkan faktor jarak maka freight cost pelayaran asing lebih mahal 74% dibanding pelayaran domestik, serta dari skenario yang dilakukan semakin dilonggarkan Asas Cabotage lebih meningkatkan Social Welfare sebanyak 40% dikarenakan Industrial Profit dan Consumer Surplus yang juga meningkat dalam sampel 1 teu peti kemas.