bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Multivariate-Based Provably Secure Certificateless Signature Scheme With Applications To The Internet Of Medical Things
Authors: Srivastava Vikas , Debnath Sumit Kumar 
Published: July 2022

Abstract
Over the last few years, Internet of Medical Things (IoMT) has completely transformed the healthcare industry. It is bringing out the most notable, and unprecedented impacts on human health, and has totally changed the way we look at the healthcare industry. The healthcare sector all around the globe are leapfrogging, and adopting the technology, helping in transforming drastically in a very short span of time. However, as more and more number of medical devices are being connected to IoMT, security issues like ensuring authenticity and integrity of the transmitted data are also on the rise. In view of the context, there is a need of an efficient cryptographic primitive that can address these issues in a viable manner. A signature scheme seems to be the natural choice to mitigate the security concerns. But, traditional signature schemes, both public-key-infrastructure-based and Identity-based, have their own disadvantages, which makes them unsuitable for IoMT networks. Thus, to address the security issues and problems like certificate management and key escrow, herein, we put forward the first multivariate-based certificateless signature scheme, namely, Multivariate Certificateless Signature (Mul-CLS), which is built on top of the intractability of multivariate-quadratic (MQ) problem. The fact that multivariate public key cryptosystem provides fast, post-quantum safe and efficient primitives makes it a front-runner candidate among the other post-quantum cryptography candidates. Our scheme Mul-CLS provides existential unforgeability against chosen message and chosen identity Super Type I and Super Type II adversary if solving the MQ problem is NP-hard. In addition to that, our proposed Mul-CLS presents itself as a robust and cost-friendly cryptographic building block for building IoMT networks.
EURObservational Research Programme: a bibliometric assessment of its scientific output
Authors: Rossello Xavier , Massó-van Roessel Albert , Chioncel Ovidiu , Tavazzi Luigi , Ferrari Roberto , Vahanian Alec , Gale Chris P , Popescu Bogdan A , Maggioni Aldo P 
Published: July 2022

Abstract

Aims
Given the lack of reliable observational data, a network of volunteer centres, and standardized methodological procedures, the European Society of Cardiology EURObservational Research Programme (EORP) was set up to provide a better understanding of real-world cardiovascular care and outcomes. We aimed to evaluate the scientific impact of EORP using a bibliometric approach.

Methods and Results
We collected data for each individual publication and for each individual journal with at least one EORP publication. Bibliometric indicators evaluating research performance were categorized into those evaluating EORP publications (publication-based indicators) and those assessing the journals where those papers were published (journal-based indicators). During the first ∼11 years since its inception, we found that EORP produced 189 publications, with most published in journals in the first quartile (60.9%) or the second quartile (33.5%) of the Web of Science Journal Citation Report. The total number of citations to EORP publications was 9630 (average citation per publication of 51, h-index of 54, and 29 EORP publications with ≥100 citations). Of EORP publications, 20 had an Altmetric Attention Score &gt;50 and 9 had a score &gt;100. A total of 52 EORP papers have been cited 65 times in ESC Clinical Practice Guidelines between 2013 and 2021.

Conclusion
EORP registries have contributed to impactful scientific knowledge. The high-quality metrics highlight the relevance of the EORP international cardiovascular registries to the academic community. Efforts are needed to support this, and other programmes aimed at delivering real-world evidence from independent patient data of cardiovascular care and outcomes across multiple geographies.
Spatial Polarisation*
Authors: Cerina Fabio , Dienesch Elisa , Moro Alessio , Rendall Michelle 
Published: July 2022

Abstract
We document the emergence of spatial polarisation in the United States during the 1980–2008 period. This phenomenon is characterised by stronger employment polarisation in larger cities, both at the occupational and the worker levels. We quantitatively evaluate the role of technology in generating these patterns by constructing and calibrating a spatial equilibrium model. We find that faster skill-biased technological change in larger cities can account for a substantial fraction of spatial polarisation in the United States. Counterfactual exercises suggest that the differential increase in the share of low-skilled workers across city size is due mainly to the large demand by high-skilled workers for low-skilled services and, to a smaller extent, to the higher complementarity between low- and high-skilled workers in production relative to middle-skilled workers.
Chromosome-Level Genome Assembly of the Butter Clam Saxidomus purpuratus
Authors: Kim Jungeun , Kim Hui-Su , Choi Jae-Pil , Kim Min Sun , Woo Seonock , Kim Yeonghye , Jo Yejin , Yum Seungshic , Bhak Jong 
Published: July 2022

Abstract
Herein, we provide the first whole-genome sequence of the purple butter clam (Saxidomus purpuratus), an economically important bivalve shellfish. Specifically, we sequenced and de novo assembled the genome of Sa. purpuratus based on PromethION long reads and Hi-C data. The 978-Mb genome of Sa. purpuratus comprises 19 chromosomes with 36,591 predicted protein-coding genes. The N50 length of Sa. purpuratus genome is 52 Mb, showing the highest continuous assembly among bivalve genomes. The Benchmarking by Universal Single-Copy Orthologs assessment indicated that 95.07% of complete metazoan universal single-copy orthologs (n = 954) were present in the assembly. Approximately 51% of Sa. purpuratus genome comprises repetitive sequences. Based on the high-quality Sa. purpuratus genome, we resolved half of the immune-associated genes, namely, scavenger receptor (SR) proteins, which are collinear to those in the closely related Cyclina sinensis genome. This finding suggested a high degree of conservation among immune-associated genes. Twenty-two (19%) SR proteins are tandemly duplicated in Sa. purpuratus genome, suggesting putative convergence evolution. Overall, Sa. purpuratus genome provides a new resource for the discovery of economically important traits and immune-response genes.
Highly Contiguous Genome Assemblies of the Guinea Paper Wasp (Polistes exclamans) andMischocyttarus mexicanus
Authors: Miller Sara E , Legan Andrew W , Uy Floria M K , Sheehan Michael J 
Published: July 2022

AbstractPaper wasps are a model system for the study of social evolution due to a high degree of inter- and intraspecific variation in cooperation, aggression, and visual signals of social status. Increasing the taxonomic coverage of genomic resources for this diverse clade will aid comparative genomic approaches for testing predictions about the molecular basis of social evolution. Here, we provide draft genome assemblies for two well-studied species of paper wasps, Polistes exclamans and Mischocyttarus mexicanus. The P. exclamans genome assembly is 221.5 Mb in length with a scaffold N50 of 4.11 Mb. The M. mexicanus genome assembly is 227 Mb in length with a scaffold N50 of 1.1 Mb. Genomes have low repeat content (9.54–10.75%) and low GC content (32.06–32.4%), typical of other social hymenopteran genomes. The DNA methyltransferase gene, Dnmt3 , was lost early in the evolution of Polistinae. We identified a second independent loss of Dnmt3 within hornets (genus: Vespa).
A Chromosome-Level Genome Assembly ofToona ciliata(Meliaceae)
Authors: Wang Xi , Xiao Yu , He Zi-Han , Li Ling-Ling , Song Hui Yun , Zhang Jun-Jie , Cheng Xiang , Chen Xiao-Yang , Li Pei , Hu Xin-Sheng 
Published: July 2022

AbstractToona ciliata Roem is an important timber species in the Toona genus of the Meliaceae family and an endangered species due to over-cutting and a low rate of natural regeneration in China. Although molecular markers have been applied to studying population genetic diversity, the absence of a reliable reference genome limits in-depth genetic conservation and evolutionary studies of this species. Here, we reported a high-quality assembly of the whole genome sequence of T. ciliata. The total assembled genome has 520.64 Mb in length anchored on 28 chromosomes (contig N50 = 4.48 Mb). A total of 42,159 genes were predicted after the ab initio, homology-based, and transcriptome analyses. A total of 41,284 protein-encoding genes (97.92%) were functionally annotated and 1,246 non-coding RNAs were identified in the T. ciliata genome. Phylogenomic analysis showed that T. ciliata was divergent at 15.06 (6–25) Ma from T. sinensis of the same genus Toona. This whole genome sequence provides a valuable resource to study the genetic conservation and molecular evolution of T. ciliata in the future.
Proof-of-concept, rapid, instrument-free molecular detection of Neisseria gonorrhoeae and ciprofloxacin susceptibility
Authors: Ayfan Abdulrahman K S , Macdonald Joanne , Irwin Adam D , Zowawi Hosam M , Forde Brian M , Paterson David L , Lahra Monica M , Whiley David M 
Published: July 2022

Abstract

Objectives
To develop instrument-free point-of-care methods using recombinase polymerase amplification (RPA) technology coupled with a simple lateral flow detection system to detect Neisseria gonorrhoeae and susceptibility to ciprofloxacin.

Methods
For identification of gonococcal infection, an RPA-based method was developed targeting the gonococcal porA pseudogene (NG-porA-RPA). For ciprofloxacin susceptibility, predictive WT sequences at codons 91 and 95 of the gonococcal gyrA DNase gene were targeted. Given the known complexities of SNP detection using RPA (e.g. the ability to accommodate mismatches) we trialled several different assays incorporating various additional non-template mismatches in the oligonucleotide sequences to reduce affinity for the mutant (resistant) gyrA sequences. Assays were evaluated using a bank of N. gonorrhoeae (n = 10) and non-gonococcal (n = 5) isolates and a panel of N. gonorrhoeae nucleic acid amplification test (NAAT)-positive clinical sample extracts (n = 40).

Results
The NG-porA-RPA assay was specific to N. gonorrhoeae and provided a positive percentage agreement (PPA) of 87.5% (35/40) compared with a commercial N. gonorrhoeae NAAT when applied to the 40 clinical sample extracts. For gyrA, the non-template bases successfully reduced banding intensity for double-mutant strains (mutations at both 91 and 95), but not for rarer single-mutant (91 only) strains. The most promising gyrA assay, NG-gyrA-RPA08, correctly detected 83% (25/30) of infections from NAAT-positive clinical samples confirmed to have WT gyrA sequences based on Sanger sequencing.

Conclusions
These proof-of-concept data show that RPA technology has considerable promise for detecting N. gonorrhoeae and associated antibiotic susceptibility and would offer a diagnostic-based stewardship strategy identified as urgently needed by the WHO.
Phylogenomic analysis of Salmonella Indiana ST17, an emerging MDR clonal group in China
Authors: Sun Ruan-Yang , Guo Wen-Ying , Zhang Ji-Xing , Wang Min-Ge , Wang Lin-Lin , Lian Xin-Lei , Ke Bi-Xia , Sun Jian , Ke Chang-Wen , Liu Ya-Hong , Liao Xiao-Ping , Fang Liang-Xing 
Published: July 2022

Abstract

Objectives
To reconstruct the genomic epidemiology and evolution of MDR Salmonella Indiana in China.

Methods
A total of 108 Salmonella Indiana strains were collected from humans and livestock in China. All isolates were subjected to WGS and antimicrobial susceptibility testing. Phylogenetic relationships and evolutionary analyses were conducted using WGS data from this study and the NCBI database.

Results
Almost all 108 Salmonella Indiana strains displayed the MDR phenotype. Importantly, 84 isolates possessed concurrent resistance to ciprofloxacin and cefotaxime. WGS analysis revealed that class 1 integrons on the chromosome and IncHI2 plasmids were the key vectors responsible for multiple antibiotic resistance gene (ARG) [including ESBL and plasmid-mediated quinolone resistance (PMQR) genes] transmission among Salmonella Indiana. The 108 Salmonella Indiana dataset displayed a relatively large core genome and ST17 was the predominant ST. Moreover, the global ST17 Salmonella Indiana strains could be divided into five distinct lineages, each of which was significantly associated with a geographical distribution. Genomic analysis revealed multiple antimicrobial resistance determinants and QRDR mutations in Chinese lineages, which almost did not occur in other global lineages. Using molecular clock analysis, we hypothesized that ST17 isolates have existed since 1956 and underwent a major population expansion from the 1980s to the 2000s and the genetic diversity started to decrease around 2011, probably due to geographical barriers, antimicrobial selective pressure and MDR, favouring the establishment of this prevalent multiple antibiotic-resistant lineage and local epidemics.

Conclusions
This study revealed that adaptation to antimicrobial pressure was possibly pivotal in the recent evolutionary trajectory for the clonal spread of ST17 Salmonella Indiana in China.
Safety monitoring system of personal mobility driving using deep learning
Authors: Kim Eunji , Ryu Hanyoung , Oh Hyunji , Kang Namwoo 
Published: July 2022

Abstract
Although the e-scooter sharing service market is growing as a representative last-mile mobility, the accident rate is increasing proportionally as the number of users increases. This study proposes a deep learning-based personal mobility driver monitoring system that detects inattentive driving by classifying vibration data transmitted to the e-scooter when the driver fails to concentrate on driving. First, the N-back task technique is used. The driver was stimulated by external visual and auditory factors to generate a cognitive load, and vibration data were collected through a six-axis sensor. Second, the generated vibration data were pre-processed using short-time Fourier transform and wavelet transform (WT) and then converted into an image (spectrogram). Third, four multimodal convolutional neural networks such as LeNet-5, VGG16, ResNet50, and DenseNet121 were constructed and their performance was compared to find the best architecture. Experimental results show that multimodal DenseNet121 with WT can accurately classify safe, slightly anxious, and very anxious driving conditions. The proposed model can be applied to real-time monitoring and warning systems for sharing service providers and used as a basis for insurance and legal action in the case of accidents.
Camera localization with Siamese neural networks using iterative relative pose estimation
Authors: Kim Daewoon , Ko Kwanghee 
Published: July 2022

Abstract
This paper presents a novel deep learning-based camera localization method using iterative relative pose estimation to improve the accuracy of pose estimation from a single RGB image. Although most existing deep learning-based camera localization methods are more robust for textureless cases, illumination changes, and occlusions, they are less accurate than other non-deep learning-based methods. The proposed method improved the localization accuracy by using the relative poses between the input image and the training dataset images. It simultaneously trained the network for the absolute poses of the input images and their relative poses using Siamese networks. In the inference stage, it estimated the absolute pose of a query image and iteratively updated the pose using relative pose information. Real world examples with widely used camera localization datasets and our dataset were utilized to validate the performance of the proposed method, which exhibited higher localization accuracy than the state-of-the-art deep learning-based camera localization methods. In the end, the application of the proposed method to augmented reality was presented.
Emergency multivisceral resection for spontaneous haemorrhage rupture of huge solid pseudopapillary neoplasm of the pancreas during pregnancy
Authors: Ahmad Raheel , Baia Marco , Naumann David N , Mahmood Fahad , Tirotta Fabio , Ford Samuel , Desai Anant , Almond Max 
Published: July 2022

AbstractSolid pseudopapillary neoplasm (SPN) of the pancreas is a rare malignancy with a low malignant potential and strong female preponderance. Diagnosis during pregnancy is extraordinary, and management must consider the risks to the mother and foetus of tumour growth and rupture. A large 35-cm SPN was identified on magnetic resonance imaging (MRI) in a 24-year-old woman at 6 weeks of gestation following presentation with an abdominal mass. Surgery was delayed to allow the foetus to reach as close to term as possible because surveillance MRIs showed incremental mass growth. Emergency c-section was undertaken at 35 weeks of gestation due to persistent tachycardia and suspected haemorrhage into the tumour. A Hb of 70 g/l post-delivery despite four units of RBCs and an albumin of 11 g/l necessitated urgent multivisceral surgery. Surgical resection is the mainstay of treatment for SPN. However, the strategy of choice during pregnancy remains undetermined, with more recent reports delaying surgery until post-partum.
Sculpture and Faith at St Paul’s Cathedral, c. 1796–1913: Introduction
Authors: Coughlan Marjorie , Edwards Jason , Sullivan Greg 
Published: July 2022

Abstract
In our introduction, we establish the original conference context of the 15 following position papers, emphasizing that the papers represent a conversation between participants, each of whom had been allocated a single monument from St Paul’s Cathedral in the period between c. 1796 and 1913, to think about the memorial’s visual and material richness and complexity, as well as its immediate and wider cathedral location, and broader discursive contexts. We map out the historiographical contexts of the papers, within the contexts of sculpture studies, studies of church monuments, interdisciplinary studies of the nineteenth century, and histories of Victorian Christianity – and especially Anglicanism – as it intersects with other world religions, and seeks to evangelize both at home and abroad.
Mediated Community and Participatory Blackface in Gillette Original Community Sing (CBS, 1936–1937)
Authors: Morgan-Ellis Esther M 
Published: July 2022

ABSTRACT
In the United States, sing-along radio programmes became common in the 1930s. These programmes aired locally, regionally, and nationally, and they took various approaches to audience participation. Although categorized as radio participation shows, sing-along programmes were unique in that they prompted scripted musical participation by home listeners during the course of the broadcast. This article examines the most successful sing-along programme, Gillette Original Community Sing, which broadcast on the CBS network in 1936 and 1937. Participants were encouraged to imagine themselves as part of a numberless mediated community that included both audible singers in the studio audience and unheard singers spread across the continent. This community, however, was clearly bounded in terms of race. A detailed analysis of the Community Sing repertory reveals that the African American experience—as imagined primarily by white songwriters and often using blackface dialect—was the third most common song topic. By singing these songs, especially in the proximity of minstrel sketches, home listeners participated in mediated blackface performances that addressed racial anxieties and constructed white identity.
For how long are particles accelerated in shells of recurrent novae?
Authors: Bednarek W 
Published: July 2022

ABSTRACT
Galactic novae are at present a well established class of γ-ray sources. We wonder for how long the mechanism of acceleration of electrons operates in the shells of novae. In order to put constraints on the time-scale of the electron acceleration, we consider a specific model for the injection and propagation of electrons within the shell of the recurrent nova RS Ophiuchi. We calculate the equilibrium spectra of electrons within the nova shell and the γ-ray fluxes produced by these electrons in the Comptonization of the soft radiation from the red giant within a nova binary system and also radiation from the nova photosphere. We investigate a two-component time-dependent model in which a spherically ejected nova shell propagates freely in the polar region of a nova binary system. However, the shell is significantly decelerated in the dense equatorial region of the binary system. We discuss the conditions under which electrons can produce γ-rays that might be detectable by present and/or future γ-ray observatories. It is concluded that freely expanding shells of novae in the optimal case (strongly magnetized shell and efficiency of acceleration of electrons of the order of 10 per cent) can produce TeV γ-rays within the sensitivity of the Cherenkov Telescope Array within 1–2 yr of explosion only. On the other hand, decelerated shells of novae have a chance to be detected during the whole recurrence period of RS Ophiuchi, i.e. ∼15 yr.
Robertsonian Fusion and Centromere Repositioning Contributed to the Formation of Satellite-free Centromeres During the Evolution of Zebras
Authors: Cappelletti Eleonora , Piras Francesca M , Sola Lorenzo , Santagostino Marco , Abdelgadir Wasma A , Raimondi Elena , Lescai Francesco , Nergadze Solomon G , Giulotto Elena 
Published: July 2022

AbstractCentromeres are epigenetically specified by the histone H3 variant CENP-A and typically associated with highly repetitive satellite DNA. We previously discovered natural satellite-free neocentromeres in Equus caballus and Equus asinus. Here, through ChIP-seq with an anti-CENP-A antibody, we found an extraordinarily high number of centromeres lacking satellite DNA in the zebras Equus burchelli (15 of 22) and Equus grevyi (13 of 23), demonstrating that the absence of satellite DNA at the majority of centromeres is compatible with genome stability and species survival and challenging the role of satellite DNA in centromere function. Nine satellite-free centromeres are shared between the two species in agreement with their recent separation. We assembled all centromeric regions and improved the reference genome of E. burchelli. Sequence analysis of the CENP-A binding domains revealed that they are LINE-1 and AT-rich with four of them showing DNA amplification. In the two zebras, satellite-free centromeres emerged from centromere repositioning or following Robertsonian fusion. In five chromosomes, the centromeric function arose near the fusion points, which are located within regions marked by traces of ancestral pericentromeric sequences. Therefore, besides centromere repositioning, Robertsonian fusions are an important source of satellite-free centromeres during evolution. Finally, in one case, a satellite-free centromere was seeded on an inversion breakpoint. At 11 chromosomes, whose primary constrictions seemed to be associated with satellite repeats by cytogenetic analysis, satellite-free neocentromeres were instead located near the ancestral inactivated satellite-based centromeres; therefore, the centromeric function has shifted away from a satellite repeat containing locus to a satellite-free new position.