bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phytochemical analysis and antioxidant activity of twigs and leaves extracts of Tertraclinis articulata (Vahl) Masters
Authors: zerkani Hannou , ZEKRI Nadia , TAGNAOUT Imane , FADILI Kamal , AMALICH Smail , ELAZZOUZI Hanane , BOUHRIM Mohamed , ZAIR Touriya 
Published: August 2022

Abstract
To research natural antioxidants, the present study aims to extract and identify new substances of natural origin through the phytochemical study and the evaluation of the antioxidant activity of extracts of twigs and leaves of Tetraclinis articulata (Vahl) Masters, harvested from the Khenifra region (Middle Atlas, Morocco). The Phytochemical screening, based on precipitation and complexation reactions, showed that the twigs and leaves of T. articulata contain flavonoids, tannins, alkaloids, mucilages, sterols and triterpenes. The extraction of the phenolic compounds was done using a Soxhlet apparatus. The assays of polyphenols, flavonoids and condensed tannins of the obtained extracts showed that the highest content of polyphenols was recorded by the ethyl acetate extract (654.69 ± 0.33mgEAG/gE). Concerning the flavonoids, the hydroethanolic extract records the highest content (20,31 ± 0,02mgEQ/gE). For the condensed tannins, the highest content was observed by the extract of the residual phase (27.72 ± 0.11mgEC/gE). Indeed, due to the analysis by HPLC/SM, we were able to identify in the E.MeOH of T. articulata seven flavonic glycosides which are Catechin, B-type (Epi) catechin dimer, gallocatechin, Myricetin-hexose, Myrcetin-rhamnose, Quercetin-3-o-Rhamnoside and kampferol-deoxyhexose. The in vitro evaluation of the antioxidant activity of T. articulata extracts was performed by DPPH and FRAP methods. The extracts of T. Articulata showed a significant antioxidant power. The lowest IC50 and EC0.5 were recorded by E. EtOH. These low concentrations (IC50 and CE0.5) obtained by DPPH and FRAP are 70 ± 0.07 µg/ml and 104.12 ± 1.02 µg/ml, respectively. This study revealed that the extracts of T. articulata are potentially important due to their richness in secondary metabolites of its antioxidant power.
Revisiting controversies on the measurement of Human development
Authors: DIALGA Issaka 
Published: August 2022

AbstractA decade after Klugman et al's (2011) magisterial criticism on the HDI, controversies on the issue of measurement of human development remains alive. This paper updates this debate by focusing on 3 key issues: i) does the measurement of the HDI through a single value have empirical proof? ii) Is the equal weighting of components of the index statistically justified? iii) What weighting system should be adopted when taking into account the heterogeneity of the countries? The paper addresses these issues using Principal Components Analysis (PCA) on the 2020 HDI data. PCA results support the measurement of human progress through a composite index. The paper shows that the choice of equal weights (1/3, 1/3, 1/3) is valid in the new HDI calculations. However, when taking into account the heterogeneity of the ranked countries, weights should be unequal. The health dimension, the knowledge one and the decent standard of living should be respectively weighted as follow: (0.357, 0.354, 0.289) for the first set of homogeneous countries called “high human development countries’’; (0.468, 0.499, 0.03) for the second ones called “medium human development countries” and (0.271, 0.370, 0.359) for the third ones called “low human development countries”. As a consequence, these unequal weights schemes modify the country specific score and then, the UNDP 2020 ranking.JEL Codes:C1, C180, I32, O57
The ultrasonic vibration-assisted polishing material removal model of tilted cylindrical polishing tool based on BK7 glass
Authors: Cui Zhijie , Liang Yingdong , Chen Xin , Meng Fanwei , Wang Zixuan , Yu Tianbiao , Zhao Ji 
Published: August 2022

Abstract
BK7 glass is widely used in various optical instruments as common ceramic material. However, there are still several difficulties in the polishing process due to its material properties. Ultrasonic vibration-assisted polishing (UVAP) is used widely for its excellent material removal properties. However, there are few researches on the model of UVAP material removal for tilted. Therefore, this paper investigates this problem. A model of UVAP material removal was established for titled column polishing; The pressure distribution and velocity distribution in the contact zone were modeled by means of experiments and geometric analysis. A series of orthogonal experiments were conducted, and the experimental results showed that the coefficient of determination was above 0.9 after fitting the actual profile to the predicted profile. The results of the orthogonal experiments were also analyzed by ANOVA. The predict error of maximum removal depth was less than 13.12%. The error of material removal rate (MRR) was less than 9.24%. By PSD analysis, it was found that the introduction of ultrasonic amplitude has a good effect on suppressing the medium and high frequency errors on the machined surface. The novel model can be used to optimize machining parameters and provide theoretical support for complex parts polishing.
Effects of application of rice husk biochar and limestone on cadmium accumulation in wheat under glasshouse and field conditions
Authors: Niu Zehui , Ma Jiayan , Fang Xianzhi , Xue Zhaokun , Ye Zhenqian 
Published: August 2022

Abstract
Cadmium (Cd) has seriously threatened the safe production of food crops. Passivator amendments are commonly used to control the soil Cd availability. Yet, few studies are tested to explore the effect of the combination of various amendments. Here, we investigated the effects of different amendments (2% rice husk biochar, 2% limestone, and 1% rice husk biochar +1% limestone) on the growth and Cd accumulation of wheat in pot and field experiments. The results showed that under the low soil Cd condition, the maximum increase of soil pH (1.83) was found in the limestone treatment compared to CK in pot experiment. Compared with the CK，the treatment of rice husk biochar decreased soil Cd availability and grain Cd content by about 25% and 31.2%, respectively. In contrast, under high soil Cd condition, the highest soil pH was observed in limestone, while the lowest soil Cd availability and grain Cd concentrations were found in rice husk biochar treatment. In the field experiment, the treatment of 1% rice husk biochar +1% limestone caused a significant increase of soil pH by about 28.2%, whereas the treatment of 2% rice husk biochar reduced soil Cd availability and grain Cd content by about 38.9% and 38.5% compared to the CK. Therefore, rice husk biochar showed great potential to reduce Cd availability and ensure safe food production.
"Influence of lymph node degeneration on metastases in prostate cancer - or why we must look for a needle in a haystack"
Authors: Gödde Daniel , Degener Stephan , Walles Christine , Keller Rosalie , Dreger Nici-Markus , Graf Katharina , Rundstedt Friedrich Carl , Kvasnicka Hans-Michael , Krege Susanne , Störkel Stephan 
Published: August 2022

Abstract
BackgroundTo evaluate the incidence of lymph node degeneration and its association with nodal metastatic pattern in prostate cancer. MethodsA retrospective analysis of the submitted lymph node specimen of 390 prostatectomies in 2011 was performed. All lymph nodes were histologically re-evaluated and the degree of lymph node degeneration e.g. lipomatous atrophy, capsular and framework fibrosis, and calcifications as well as the lymph node size were recorded. Lymph node degeneration was compared in the anatomic regions of the pelvis as well as in lymph nodes with and without metastases of prostatic cancer.Results81 of 6026 lymph nodes demonstrated metastases and a complete histological examination of 5173 lymph nodes was feasible. The incidence of lymph node degeneration was different across the various landing sites. Lymph node metastases were primarily detected in less degenerative and therefore more functional lymph nodes. In metastatic vs. non-metastatic lymph nodes low lipomatous atrophy was reported in 84,0% vs. 66,7% (p=0,004), capsular fibrosis in 14,8% vs. 35,4% (p < 0.001), calcifications in 35,8% vs.46,1% (p=0,072) and framework fibrosis in 69,8% vs. 75,3% (p=0,53). Metastases were also identified more frequently in larger than in smaller lymph nodes (63,0% vs. 47,5%; p=0,007).ConclusionsDegenerative changes in pelvic lymph nodes are commonly detectable but occur with variable frequency in the various nodal landing sites in the pelvis. The degree of lymph node degeneration of single lymph nodes has a significant influence on whether a lymph node is infiltrated by tumor cells and may harbour metastases.
Bifidobacteria Define Gut Microbiome Profiles of Golden Lion Tamarin (Leontopithecus rosalia) and Marmoset (Callithrix sp.) Metagenomic Shotgun Pools
Authors: Malukiewicz Joanna , D'arc Mirela , Dias Ceclia A. , Cartwright Reed A. , Grativol Adriana D. , Moreira Silvia Bahadian , Souza Antonizete R , Tavares Maria Clotilde Henriques , Pissinatti Alcides , Ruiz-Miranda Carlos R. , Santos André F. A. 
Published: August 2022

Abstract
Gut microbiome disruptions may lead to adverse effects on wildlife fitness and viability, thus maintaining host microbiota biodiversity needs to become an integral part of wildlife conservation. The highly-endangered callitrichid golden lion tamarin (GLT-Leontopithecus rosalia) is a rare conservation success, but allochthonous callitrichid marmosets (Callithrix) serve as principle ecological GLT threats. However, incorporation of microbiome approaches to GLT conservation is impeded by limited gut microbiome studies of Brazilian primates. Here, we carried out analysis of metagenomic pools from a total of 80 individuals of wild and captive GLTs and marmosets. More specifically, we analyzed the bacterial component of ultra-filtered samples originally collected as part of a virome profiling study. The major findings of this study are consistent with previous studies in showing that Bifidobacterium, a bacterial species important to the metabolism of tree gums consumed by callitrichids, is an important component of the callitrichid gut microbiome - although GTLs and marmosets were enriched for different species of Bifidobacterium. Additionally, the composition of GLT and marmoset gut microbiota is sensitive to host environmental factors. Overall, our data expands baseline gut microbiome data for callitrichids to allow for the development of new tools to improve their management and conservation.
An effective threshold based technique for retinal image blood vessel segmentation using average &amp; Gaussian filters
Authors: Ray Rahul , Jena Sudarson , Parida Priyadarsan 
Published: August 2022

Abstract
The fundamental components of automated retinal blood vessel segmentation for eye disease screening systems are segmentation algorithms, retinal blood vessel datasets, classification algorithms, performance measure parameters and noise removing filters etc. This paper is presenting retinal blood vessel segmentation techniques on 2D retinal images captured by fundus camera and examining the performance of different algorithms for a better and accurate result. The goal of this study is to comprehensively investigate and assess retinal blood vessel extraction algorithms using publicly accessible HRF-DR and INSPIRE-AVR datasets, with a focus on important performance measurements and characteristics. The effectiveness of our methodology is measured using the performance metrics like Sensitivity, Specificity and Accuracy with 94.27%, 87.86% and 95.61% for HRF-DR dataset and 91.10%, 86.97% and 95.16% for INSPIRE AVR dataset respectively.
Nonlinear vibration analysis of fractional viscoelastic nanobeam
Authors: Qiu Meifeng , Lei Dongxia , Ou Zhiying 
Published: August 2022

Abstract
Considering the size-dependent influence ignored by classical continuum mechanics, a new non-classical Euler-Bernoulli beam model is proposed in this paper. The new fractional viscoelastic nanobeam model is set up by using the fractional viscoelastic Kelvin-Voigt model and Hamilton's principle. And the new model studies the total effects of nonlocal elasticity, modified couple stress, and surface energy. The model represented the fractional integral-partial differential governing equation is solved by Galerkin's and predictor-corrector method. Firstly, the effects of nonlocal elasticity, modified couple stress, surface energy, and their coupling impact on the nonlinear time response of free vibration of fractional viscoelastic nanobeam are analyzed. Secondly, the nonlinear time response of free and forced vibration of fractional viscoelastic nanobeam are studied in the context of the nonlocal couple-stress elasticity and the surface energy theory. Finally, the effects of initial displacement, fractional order, viscoelasticity coefficient, damping coefficient, length-to-thickness ratio, force amplitude, and excitation frequency on the nonlinear vibration time response of the fractional viscoelastic nanobeam are analyzed.
Thrombus-targeted Nano-agents for NIR-II Diagnostic Fluorescence Imaging-guided Flap Thromboembolism Multi-model Therapy
Authors: cao Zichen , Han Wei , zhang xinyu , wei zheng , song chuanhui , zou huihui , ran jianchuan , zhang hongbo , xie diya , han shengwei , wang yufeng , cai yu 
Published: August 2022

Abstract
In oral and maxillofacial surgery, flap repair plays an essential role in the quality of postoperative life, but thrombosis is fatal for the survival of the patients. Besides, some postoperative thrombotic diseases, such as pulmonary embolism, also intimidate patients' life. The traditional diagnostic methods are still limited by a large amount of hardware and suffer from inconvenience, delay, and subjectivity. Moreover, the treatments mainly rely upon thrombolytics, such as urokinase (UK) plasminogen activator, which may cause bleeding risk, especially intracerebral hemorrhage. Herein, a kind of poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) containing a first near-infrared window (NIR-I) phototheranostic agent Y8 and urokinase plasminogen activator (UK) as the core, and modified with the fibrin-targeting peptide GPRPP on the surface (GPRPP-Y8U@P) were developed for the flap and postoperative thromboembolism treatment. The conjugated molecule Y8 endows GPRPP-Y8U@P with the capacity of NIR-II imaging and excellent photothermal/photodynamic therapeutic effects. In vivo experiments demonstrated that GPRPP-Y8U@P could quickly locate thrombus by NIR-II fluorescence imaging, and semi-quantitative analysis of the embolized blood vessels' paraffin section verified its thrombolytic efficiency. Additionally, the urokinase trapped in the NPs would not result in nonspecific bleeding, tremendously improving physical security and curative effects with minimizing side effects. Overall, the advantages of GPRPP-Y8U@P, such as precise localization of the thrombus, thrombus ablation in the site, and mild side effects, demonstrate the attractiveness of this approach for effective clinical monitoring of thrombus therapy.
Performance Evaluation of IEEE 802.11p EDCA for Vehicular Safety Communication using Semi-Markov Process
Authors: HU LIN 
Published: August 2022

Abstract
In this paper, a new semi-Markov process (SMP) based model is devised to evaluate the IEEE 802.11p enhanced distributed channel access (EDCA) broadcast performance for vehicular safety communication. Differing from the existing SMP analytical models, the proposed model takes the virtual collision among various prioritized access categories (ACs) inside each vehicle into consideration. Moreover, in contrast to the Markov chain-based models, our model is simpler but with approximate accuracy. Concretely, we first capture the behavior of each AC’s backoff entity using SMP. Then, the parameters of interest in the vehicular ad hoc network (VANET) such as packet transmission probability, conditional collision probability, and saturation throughput are derived. Finally, via MATLAB simulations, we demonstrate that the newly developed model achieves comparable accuracy in calculating these output parameters while its complexity and computation time is around onetenth of that with the Markov chain-based models. Therefore, the proposed model is more suitable for real-time performance analysis of IEEE 802.11p EDCA safety communication in a freeway scenario.
Comparison of physicochemical properties of sorghum extract by ethanol concentration and its anti-adipogenic effect in 3T3-L1
Authors: Jung Seyoung , Jeong Eun Woo , Baek Youjin , Go Gwang-woong , Lee Hyeon Gyu 
Published: August 2022

Abstract
Sorghum is an important cereal source of phenolic compounds, with potential health-promoting benefits. This study evaluated the phenolic content and antioxidant and anti-obesity effects of sorghum extract (SE) prepared using three solvent systems: 50% (SE50), 80% (SE80), and 100% (SE100) ethanol. The results showed that SE50 exhibited the highest total polyphenol, flavonoid, and tannin content. In addition, SE50 showed significantly higher antioxidant capacity than the other extracts, as determined using 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity and ferric reducing antioxidant power assays. Interestingly, the SE50 significantly inhibited lipid accumulation in 3T3-L1 preadipocytes; however, extracts using SE80 and SE100 had no such beneficial effects. Furthermore, SE50 significantly downregulated the mRNA expression of adipogenic genes (Cebpα, Pparγ, and Fabp4) and lipogenic genes (Srebp1c, Fas, and Scd1). These results suggest that the phenolic contents, antioxidant, and anti-obesity activities of 50% ethanol extract are superior to those of other extracts, and it could be used as a functional food ingredient for anti-obesity.
Advanced adjustable ionic conductivity of polybenzimidazole membranes with arrayed two-dimensional AlOOH nanosheets for water electrolysis
Authors: Qiu Zhi , Wang Lihua , He Min , Yun Yanbin 
Published: August 2022

Abstract
Polybenzimidazole (PBI) membrane is promising but limited by its lower ion conductivity when used in the energy field. Two-dimension (2D) layered hydroxides with abundant hydroxyl groups could accelerate ion transport. However, the ionic conductivity cannot be adjusted when the 2D nanosheet is introduced by blending or spraying methods. Here, a series of novel arrayed 2D AlOOH-PBI composite membranes with adjustable ionic conductivity were prepared via the in-situ growing-etching method through the control of the thickness of nanosheets. The hydroxide ion conductivity of the proposed membrane was about 5.5-fold higher than that of pristine PBI membrane. The proton conductivity also showed about 1.5-fold enhancement. Meanwhile, the membrane electrode assembly with novel membranes showed superior voltage performance of 2.07 V at a current density of 1 A cm− 2, and the long-term stability was confirmed for over 200 h at a current density of 500 mA•cm− 2 in water electrolysis. These results look prospective for the preparation of new membranes for energy applications.
Investigating self-reported efficacy of lifestyle medicine approaches to tackle erectile dysfunction: a cross-sectional eSurvey based study
Authors: El-Osta Austen , Kerr Gabriele , Alaa Aos , Asmar Marie Line El , Karki Manisha , Webber Iman , Sasco Eva Riboli , Blume Giordano , Beecken Wolf-D , Mummery David 
Published: August 2022

Abstract
BackgroundErectile dysfunction (ED) is the most common sexual dysfunction in men. Some types of ED are amenable to treatment using lifestyle medicine approaches with or without pharmacotherapy.AimInvestigate self-reported efficacy of lifestyle medicine approaches to tackle EDMethodsA cross-sectional online survey of 1177 community dwelling adults explored the prevalence and methods used to tackle ED in the community setting. We examined differences between participants with and without ED. Variables associated with ED in univariable analyses were included in a multivariable logistic regression to identify variables independently associated with the condition.OutcomesSelf-reported measure: perceived effectiveness of lifestyle medicine interventions to tackle EDResultsMost respondents (76.5%) had experienced ED, and this was associated with having a long-term condition, taking anti‑hypertensive medication, hypercholesterolaemia and obesity. Medication was the most common management strategy overall (65.9%), followed by stress management (43.5%) and weight loss (40.4%). Over half (53.9%) did not use any lifestyle modification strategies to tackle ED. Only 7.0% of ED sufferers received a mental health assessment and 29.2% received other tests (e.g., blood test, medical imaging) by GPs. Cardiovascular training was identified as the best rated strategy by its users (37.8%). Supplements (35.1%) and weight training/physical activity (32.6%) were also positively rated.Clinical implicationsStructured education to general practitioners and community dwelling adults about the impact of lifestyle behaviour modification and how this could influence the appearance or trajectory of ED could help improve personal choice when tackling ED.Strengths and LimitationsTo our knowledge, this is the first study to collect eSurvey responses from community dwelling adults to gauge their reliance and perceived effectiveness of lifestyle medicine approaches to tackle ED. The principal limitation was the lack of follow-up, and not recording other information including lifestyle factors such as nutrition, smoking, and the use of alcohol and recreational drugs, which may have enabled a fuller exploration of the factors that could influence the primary outcome measures examined.ConclusionDespite the high prevalence of ED, there is not enough awareness in the community setting about effective and low-cost lifestyle medicine strategies, including cardiovascular training and the use of supplements and weight training, to help tackle this common condition
High-order and V_0-stable methods for solving the Volterra integral equations of the second kind
Authors: Amiri Sadegh , Hajipour Mojtaba 
Published: August 2022

Abstract
The aim of this paper is to investigate some second- and third-order numerical methods for solving the Volterra integral equations (VIEs) of the second kind. The proposed numerical methods preserve the V_0-stability property for both single and system of the VIEs. Numerical simulations show that these methods are successful for various types of the VIEs and their computational cost are less than the other methods in literature.
A comparative Study for determination of 10-HDA in various Indian Royal Jelly samples using HPLC, HPTLC, and LC-MS/MS Techniques
Authors: Dubey Rahul N. , Sathiyanarayanan L , Rao Laxmi , Mohite Suhas 
Published: August 2022

Abstract

Bees, Apis mellifera, are precious natural resources that produce a variety of health-promoting bioactive compounds. Since it is a bee-derived product, the composition and contents of Royal Jelly (RJ) vary. The discrepancies found are most likely attributable to the variable number of samples collected from various locations and at different stages of the manufacturing process, therefore it becomes a possible source of adulteration. To ensure the quality of the product it is necessary to define and set quality control levels before its commercialization. 10-Hydroxy Decenoic acid (10-HDA) is a unique component specifically found in RJ and it is a major constituent that assures the quality of a product. Although the uniqueness of this compound is well known no attempt has been made to estimate its content in Indian Royal Jelly. The present study aimed to the development of a rapid, precise, stable, and robust method for 10-HDA determination, using High-performance Liquid Chromatography (HPLC), High-performance Thin Layer Chromatography (HPTLC), and Liquid Chromatography-Mass Spectroscopy/ Mass Spectroscopy (LC-MS/MS), and to compare the performance of each with others. The applicability of these methods was tested on Indian Royal Jelly (IRJ) samples procured from three different regions of India to determine the quality of the product and it was found that IRJ-II showed highest 10-HDA content.