bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design and Analysis of wide bandwidth Quad ‘e’ mirror-shaped metamaterial for Wi-Fi and Satellite Applications
Authors: . Ankit , Kishor Kamal , Sinha Ravindra Kumar 
Published: June 2022

Abstract
In this paper, we report a novel design of wide bandwidth Quad ‘e’ mirror-shaped metamaterial (MTM) structure for Wi-Fi and Satellite Applications. Further, the geometrical parameters of the copper-based metamaterial on FR- 4 epoxy resin fiber substrate is optimized and analyzed for a triple-band operation in the frequency range of 0.1 GHz-16 GHz. The proposed design exhibits left-handed characteristics over the three (L, C and Ku) frequency bands in microwave regime. The electric field, magnetic field and surface current distribution of the proposed MTM unit has been studied at three resonance frequencies (𝑓𝑟) namely 1.4 GHz, 5.0 GHz and 14.8 GHz. The effective electromagnetic parameters for the MTM were calculated using the obtained Propagation (transmission and reflection) characteristics. The unit cell provides negative permittivity (𝜀𝑟 ) in the region 0.5-1 GHz and a broad negative permeability (𝜇𝑟 ) in the 9-16 GHz region. The structure exhibits a negative refractive index (𝜂𝑟 ) in the region 0.5-1 GHz, 3-3.5 GHz, and 9-12 GHz. The effects of dielectric materials, design parameters, resonator width (𝑤𝑟), substrate thickness (𝑡𝑠), middle gap width (r), and the influence of different metal conductors of unit cell on resonance frequencies were also investigated. The proposed design has an unprecedented effective medium ratio (EMR) value of 13.37, implying better effectiveness and compactness of the Quad ‘e’ mirror-shaped metamaterial. The designed structure could be extremely useful for design and development of compact wide bandwidth devices for Wi-Fi and satellite applications.
Differences in trauma injury patterns and severity between intentional and accidental fall from a height: A Japanese nationwide trauma database study
Authors: Terayama Takero , Toda Hiroyuki , Saito Daizo , Tanaka Yoshihiro , Yoshino Aihide 
Published: June 2022

Abstract
Background
Fall from a height is a common cause of trauma requiring emergency care; in many cases, the trauma team needs to urgently develop the initial treatment strategy. The mechanism of injury (intentional or accidental) is an important factor in predicting trauma patterns and severity. We aimed to describe how the severity of injuries in each body region contributes to overall trauma severity and skeletal trauma patterns in intentional and accidental falls.
Methods
Data were obtained from a nationwide trauma database between January 1, 2004 and May 31, 2019. Patients aged ≥ 18 years and injured by fall from a height were included. The median Abbreviated Injury Scale (AIS) score for the Injury Severity Score (ISS) for each body region (region 1 [head, face, and neck], region 2 [thorax], region 3 [abdomen], region 4 [lower extremity and pelvis], and region 5 [upper extremity]) was investigated. Skeletal injury patterns were classified into four groups: group I (intentional/severe), group II (accidental/severe), group III (intentional/not severe), and group IV (accidental/not severe). Severe trauma was defined as a trauma with an ISS of 16 or more. The comparison between groups was assessed using the chi-square test and Mann–Whitney U test.
Results
Among the 342,263 patients enrolled in the database, 28,409 met the inclusion criteria: 6,812 in group I, 11,754 in group II, 2,384 in group III, and 7,459 in group IV. The intentional group showed an increase in the AIS score for the lower region (region 4) as the ISS increased, whereas the accidental group showed an increase in the AIS score for the upper region (region 1). Both groups showed an increase in the AIS score for region 2 as the ISS increased. The intentional fall group had a higher proportion of fractures in the lower extremities and pelvis.
Conclusions
There were differences in trauma patterns and trauma severity levels between patients who experienced intentional and accidental falls from a height. Our findings provide a comprehensive understanding of this topic. Further studies are required to assess the usefulness of our findings for the development of initial treatment strategies at the ED.
Comparison of different solvent extraction compositions for the analysis of phytoplankton pigments and lipids using a rapid and sensitive LC-MS method
Authors: Shankar Uttara , Lenka Sangram K. , Ackland M. Leigh , Callahan Damien L. 
Published: June 2022

Abstract
Background: Carotenoids and chlorophylls are important pigments as they have antioxidant properties and some such as lutein, astaxanthin and β-carotene are used as nutraceuticals. Pigment profiles are also used as taxonomic markers for phytoplankton. There are many solvent compositions published for the extraction of phytoplankton pigments. Here we report the testing of five different commonly used solvents and compare the overall pigment and lipid profiles and abundances using liquid chromatography-mass spectrometry (LC-MS) for three microalgal species with different pigment profiles.Results: A fast and sensitive LC-MS method was developed using a C18 column with a gradient consisting of isopropanol, acetonitrile and water. A total of 18 pigments along with phosphatidylcholines (PCs), triacylglycerols (TAGs) were separated in 25 mins. An extraction solvent composition of 90% acetone provided the broadest-coverage of pigments and lipids, while ethanol/hexane resulted in the highest extraction efficiency for chlorophyll and the non-polar triacylglycerol lipids. Overall, the result for the different mixtures shows the significant impact that solvent polarity has on the overall pigment and lipid profile and that no single mixture was optimal for all targets. Complete cell lysis using mechanical disruption such as bead beating is also an important step for quantitative extraction as chemical extraction on its own does not provide reproducible results.Conclusion: A 90% acetone extraction solvent mixture provides the broadest extraction of pigments from the species Haematococcus pluvialis, Desmodesmus subspicatus and Chlorella variabilis when coupled with bead beating. This extraction solvent is comparatively safe, polar and less toxic than other solvents. It was also found that none of the common solvent mixtures tested here provided the highest extraction efficiencies across all compound groups
PET/MR: Primary Inferior Vena Cava Leiomyosarcoma, a Case Report.
Authors: RONCHI BRUNELA , Peña Gustavo , Carlos Sacchi 
Published: June 2022

Abstract
Positron emission tomography (PET) combined with a magnetic resonance (MR) scanner (PET/MR) with 18F-fluorodeoxyglucose (FDG) tracer is being used in quite a few nuclear medicine centers. The aim of this study is to illustrate two uncommon cases of primary inferior vena cava leiomyosarcoma which were formerly evaluated with anatomical images such as computed tomography and ultrasound. These techniques were inferior in the definition of the tumor and its characteristics. F-18 FDG PET/MR was essential and provided all the necessary information: its origin, local extension, anatomo-metabolic behavior, form of presentation, and distant metastasis in one single diagnostic technique .PET/MR accurately contributed to the diagnosis in a shortened period of time and therefore, in the prognosis of this disease with greater benefits. This article was previously presented as an e-poster at the 34th Annual Congress of the European Association of Nuclear Medicine.
ANN-aided Mechanophenotyping of Biological Cells Using AFM
Authors: Kamble Yuvaraj , Raj Abhishek , Thakur Atul 
Published: June 2022

Abstract
Mechanical properties of biological cells can serve as biomarkers for indicating various diseases like cancer and sickle cell disease. Hertzian model-based prediction of mechanical properties of biological cells, although most widely used, has shown to have limited potential in determining constitutive parameters of cells of uneven shape and non-linear force-indentation responses of AFM-based cell nanoindentation. We report a new artificial neural network-aided approach, which takes into account, the variation in cell shapes and their effect on the predictions in cell mechanophenotyping. We have developed an artificial neural network (ANN) model which could predict the mechanical properties of biological cells by utilizing the force vs. indentation curve of AFM and we obtained a recall of 0.98 ± 0.03 and 1 ± 0.0 for hyperelastic and elastic cells respectively for the prediction error of less than 10%. We envisage that the developed technique can be used for the validation of quantitative biomechanical markers for diagnoses of diseases like cancer and sickle cell disease which could help to improve clinical decision-making.
Centering Indigenous Knowledge in Suicide Prevention: A Critical Scoping Review
Authors: Sjoblom Erynne , Ghidei Winta , Leslie Marya , James Ashton , Bartel Reagan , Campbell Sandra , Montesanti Stephanie 
Published: June 2022

Abstract
BackgroundIndigenous peoples of Canada, United States, Australia, and New Zealand experience disproportionately high rates of suicide as a result of the collective and shared trauma experienced with colonization and ongoing marginalization. Dominant, Western approaches to suicide prevention—typically involving individual-level efforts for behavioural change via mental health professional intervention—by themselves have largely failed at addressing suicide in Indigenous populations, possibly due to cultural misalignment with Indigenous paradigms. Consequently, many Indigenous communities, organizations and governments have been undertaking more cultural and community-based approaches to suicide prevention. To provide a foundation for future research and inform prevention efforts in this context, this critical scoping review summarizes how Indigenous approaches have been integrated in suicide prevention initiatives targeting Indigenous populations.MethodsA systematic search guided by a community-based participatory research (CBPR) approach was conducted in twelve electronic bibliographic databases for academic literature and six databases for grey literature to identify relevant articles. the reference lists of articles that were selected via the search strategy were hand-searched in order to include any further articles that may have been missed. Articles were screened and assessed for eligibility. From eligible articles, data including authors, year of publication, type of publication, objectives of the study, country, target population, type of suicide prevention strategy, description of suicide prevention strategy, and main outcomes of the study were extracted. A thematic analysis approach guided by Métis knowledge and practices was also applied to synthesize and summarize the findings.ResultsFifty-six academic articles and 16 articles from the grey literature were examined. Four overarching and intersecting thematic areas emerged out of analysis of the academic and grey literature: (1) engaging culture and strengthening connectedness; (2) integrating Indigenous knowledge; (3) Indigenous self-determination; and (4) employing decolonial approaches. ConclusionsFindings demonstrate how centering Indigenous knowledge and approaches within suicide prevention positively contribute to suicide-related outcomes. Initiatives built upon comprehensive community engagement processes and which incorporate Indigenous culture, knowledge, and decolonizing methods have been shown to have substantial impact on suicide-related outcomes at the individual- and community-level. Indigenous approaches to suicide prevention are diverse, drawing on local culture, knowledge, need and priorities.
Enhancing extraction of proanthocyanidins from Chinese quince fruit by ball-milling and enzyme hydrolysis
Authors: Kong Wan-Qing , Liu Ming-Wei , Wang Shou-Tao , Gao Hui-Hui , Qin Zhao , Liu Hua-Min , Wang Xue-De , He Jing-Ren 
Published: June 2022

Abstract
Chinese quince fruit is rich in proanthocyanidins (PAs), which have antioxidant properties. This work describes a method to isolate PAs from Chinese quince fruits by a combination of ball-milling pretreatment and enzyme-assisted extraction. Untreated PA fractions (UMP), ball mill pretreated PA fractions (BMP) and enzymatically hydrolysed PA fractions (BEP-1, BEP-2, BEP-3, BEP-4) were obtained. The total PA and total phenolic contents, antioxidant activity and α-amylase inhibitory activity of the six PA samples were determined, and their structural characteristics were also analyzed. BEP and BMP fractions were structurally similar with UMP, but had more total phenolics and PAs, and had higher antioxidant activities, lower thermal stability, and lower average molecular weight. Among them, BEP-4 was the most outstanding. Its total phenolics and PAs were 750.98 ± 6.95 and 948.72 ± 3.50 mg/g extract per gram dry weight, respectively. Its DPPH, ABTS, hydroxyl radical scavenging ability, and α-amylase inhibitory capacity had maximum values of 90.38%, 98.99%, 97.89%, and 92.98%, respectively. These investigations provide a new, efficient way to isolate proanthocyanidins from Chinese quince fruits, and reveal that Chinese quince fruits may be a good source of antioxidants, worthy of further development.
18F-FDG PET/CT Radiomics Features as Predictive Biomarkers in Diffuse Large B-Cell Lymphoma
Authors: Travaini Laura Lavinia , Botta Francesca , Derenzini Enrico , Presti Giuliana Lo , Ferrari Mahila Esmeralda , Farulla Lighea Simona Airò , Radice Tommaso , Mazzara Saveria , Tarella Corrado , Pileri Stefano , Raimondi Sara , Ceci Francesco 
Published: June 2022

Abstract
Background/Aim: The aim of this study was to evaluate the association between radiomic features (RFs) extracted from baseline 18F-FDG PET/CT (FDG-PET) with progression-free survival (PFS) and overall survival (OS) in diffuse large-B-cell lymphoma (DLBCL) patients eligible for standard-of-care first line chemotherapy.Materials and Methods: Records of 376 newly diagnosed DLBCL patients who underwent baseline FDG-PET at our institution were retrospectively analyzed. Inclusion criteria were: 1) proven DLBCL; 2) FDG-PET as baseline procedure prior to first-line chemotherapy; 3) no lost follow-up. Demographic data, International Prognostic Index (IPI) and conventional PET imaging parameters were collected. FDG-PET RFs were extracted from the lesion showing the highest uptake (target lesion). A radiomic score to predict PFS and OS was obtained by multivariable Elastic Net Cox model. PFS and OS were explored with the Kaplan-Meier method and Cox proportional hazards regression methods. Radiomic univariate model, as well as clinical and clinical-radiomic multivariable models for PFS and OS were obtained. Prediction accuracy was evaluated by C-index.Results: One-hundred and twelve (n=112) patients were included (55 females, 57 males, median age 62.3 years). 9/112(8%) were stage-I, 31/112(27.7%) stage-II, 8/112(7.2%) stage-III and 64/112(57.1%) stage-IV. Median follow-up was 34.7 months (IQR 11.3-66.3). Radiomic score resulted significantly associated with both PFS and OS at Cox multivariable analysis (p<0.001), outperforming conventional PET parameters. C-index (95%CI) for PFS prediction were 0.67(0.58-0.76), 0.81(0.75-0.88) and 0.84(0.77-0.91) for clinical, radiomic and clinical-radiomic model, respectively. C-index for OS were 0.77(0.66-0.89), 0.84(0.76-0.91) and 0.90(0.81-0.98). In the Kaplan-Meier analysis on population stratified according to IPI (low-IPI vs high-IPI), the radiomic score was significant predictor of PFS (p<0.001). Conclusion: The radiomic score was significant predictive biomarker of PFS and OS in DLBCL patients. The extraction of RFs from baseline FDG-PET might be proposed in DLBCL to stratify high-risk vs. low-risk patients of relapse after first-line therapy, especially in low-IPI patients.
Long-time dynamics of stochastic reaction-diffusion benthic-drift model with strong Allee effect growth
Authors: Li Qi , Liu Shijia , Gao Yitian , Huang Zaitang 
Published: June 2022

Abstract
In the paper, we consider the long-time dynamics of stochastic reaction-diffusion benthic drift model with strong Allee effect growth. Firstly, we establish the global existence and uniqueness of solutions, persistence and extinction. Secondly, under some suitable conditions , we prove the existence and uniqueness of stationary distribution. Finally, we obtain a large deviation result.
A retrospective study of treatment and outcomes of patients with lymphoma undergoing hematopoietic stem cell transplantation
Authors: Sezgin Merve Gozde , Bektas Hicran 
Published: June 2022

Abstract
PurposeEarly evaluation of symptoms and taking appropriate preventive measures can improve outcomes for patients with lymphoma undergoing hematopoietic stem cell transplantation. This study was conducted to examine the treatment and outcomes of patients with lymphoma undergoing hematopoietic stem cell transplantation. MethodsPatients with lymphoma (n=64) undergoing SCT at a university hospital between June 15, 2018 and June 15, 2020 were selected for retrospective study. The medical treatments of patients were obtained from the records on the Hospital Information Management System database. The study was reported following the STROBE checklist. Standard deviation, arithmetic mean, frequency, percentage test, t-test, chi-square, Fisher’s exact test, Mann-Whitney U test, Independent t-test, and multivariate logistic regression analysis were used to analyze the data.ResultsThe mean age of patients was 48.25±16.93. Although relapse developed in 26 patients with lymphoma, remission was achieved in 38 patients. The incidence of skin graft-versus-host disease (GVHD) symptoms in patients with relapse was found to be significantly higher than in patients in remission. The most common symptoms seen in patients undergoing stem cell transplantation were oral mucositis, febrile neutropenia, and anemia. Most patients were found to receive oral care, antibiotic treatment, and granulocyte-colony stimulating factor (G-CSF) treatment following SCT. ConclusionsPatients experienced severe symptoms due to HSCT, and necessary treatment was applied for the symptoms. Further clinical studies must determine the symptoms and patient outcomes associated with SCT.
Epidemiology of nosocomial Staphylococcus epidermidis and Acinetobacter baumannii infections in a Hospital Neonatal Intensive Care Unit
Authors: Nayeri Fatemeh , Dalili Hosein , Shariat Mamak , Farrokhzad Nahid , Abouhamzeh Kosar , Sahebi Leyla 
Published: June 2022

Abstract
Objective: Outbreaks of nosocomial infections in extreme conditions result in morbidity and mortality. This study aimed to investigate epidemiology of Staphylococcus epidermidis (s. epidermidis) and Acinetobacter baumannii (A.baumannii) outbreaks and, the associated predisposing factors in neonatal intensive care unit (NICU). Methods: This retrospective cohort study was conducted on 29 cases of nosocomial infection by S. epidermidis, and 33 neonates with A. baumannii in NICU of Valiasr hospital, a tertiary hospital in Tehran, Iran, between 2014 and 2017 (within a 45-month period). The medical and demographic information documented by the hospital registry system was used for analyzing. Results: The trend of A. baumannii infection in various years as followed: 1 infection in 2014, 11 in 2015, 20 in 2016 and 1 in 2017. These amounts in S. epidermidis were 7 in 2014, 7 in 2015, 11 in 2016, and 4 in 2017. Mortality proportion (%) in neonates with S. epidermidis and A. baumannii infection was at 8.3 and 32.1, respectively (P-Value=0.001). There was a strong positive correlation between number of infected neonates (A. baumannii and S. epidermidis) in month and average of prescribed antibiotics before incidence of nosocomial infection in every baby in that month (P-Value< 0.003). Fluconazole prescription before incidence of nosocomial infection were associated with the A. baumannii infection in month too (P-Value= 0.04). Amikacin prescription had adjusted correlation on increasing of A. baumannii and E. epidermidis infection in month. Conclusion: It seems hospitalization duration and medication prescriptions management plays an important role in reducing the outbreaks of nosocomial infections
The diurnal emission of floral scent in oncidium hybrid orchid is controlled by CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) through the direct regulation on terpene synthase
Authors: Yeh Chao-Wei , Zhong Hui-Qin , Ho Yung-Feng , Tien Zhi-Hong , Yeh Kai-Wun 
Published: June 2022

Abstract
Background: To adapt the periodic fluctuation of environmental factors, plants are subtle to monitor the natural variation for the growth and development. It is well known that the daily activities and physiological functions in coordination with the natural variation are regulated by circadian clock genes. The circadian emission of floral scents is one of the rhythmic physiological activity controlled by circadian clock genes. Here, we study the circadian emission pattern and molecular mechanism of floral terpenoids compounds (ocimene/linalool) in Oncidium Sharry Baby (Onc. SB) orchid, which were diurnally emitted under light condition. Results: GC-Mass analysis revealed that Onc. SB periodically emitted ocimene and linalool during 6:00AM to 2:00PM daily. Terpene synthase, one of the key gene in the terpenoid biosynthetic pathway is expressed in coordination with scent emission. Investigation on the promoter structure of terpene synthase revealed a circadian binding site (CBS), 5’-AGATTTTT-3’ for the binding motif of CIRCADIAN CLOCK ASSOCIATED1 (CCA1) transcription factor. EMSA data performed confirms the binding affinity between CCA1 protein and CBS of cis-acting DNA element. It suggests that the diurnal circadian emission of floral scent is controlled by CCA1.Conclusions: The work validates that the mechanism of circadian emission of floral scents in Onc. SB is controlled by the oscillator gene, CCA1(CIRCADIAN CLOCK ASSOCIATED 1) under light condition. CCA1 transcription factor regulates terpene synthase (TPS) by direct binding on CBS motif, 5’-AGATTTTT-3’ of promoter region. The circadian expression of TPS is the key gene to affect the biosynthesis and emission of floral scent in Onc. Sharry Baby.
Rapid increase of Mediterranean Sea Surface Temperature from 1982 to 2020
Authors: Rasul Azad , Aziz Kaka Jaafar 
Published: June 2022

Abstract
Intergovernmental Panel on Climate Change (IPCC) considers Mediterranean Sea a climate change hotspot, particularly it is vulnerable to increasing sea surface temperature. The research aimed to highlight the trend of Sea Surface Temperature (SST) of Mediterranean and analysis spatial variability of SST change from 1982 to 2020. Forty years SST of NOAA of AVHRR Pathfinder version 5.3 was deployed in the study. The data is processed in Google Earth Engine, cloud based remote sensing platform. The results display a rapid increase of SST of the sea occurred in mean SST (1.49°C) followed by maximum SST (0.91°C). Spatially, highest increase of SST (1–2°C) mainly happened in the eastern part of the sea. Monthly data indicated the highest increase in mean SST happened during June, July and May by 2.51, 2.28 and 2.23°C, respectively. Increasing of SST affects evapotranspiration, precipitation, and marine life but is also influenced by the increasing salinity of the sea at the same time.