bluuebunny/crossref_metadata_2025_split huggingface dataset:
Combinatorial radiation therapy for prostate cancer with seminal vesicle invasion
Authors: Makarova K. S. , Gumenetskaya Yu. V. , Biryukov V. A. , Strikanova I. A. , Kireeva T. A. , Lepilina O. G. , Karyakin O. B. , Ivanov S. A. , Kaprin A. D. 
Published: February 2022

Background. It seems advisable to investigate the feasibility of radiation therapy combined with hormone therapy to treat locally advanced prostate cancer. Combination of two ways to deliver ionizing radiation doses enables us to elevate a total tumor dose and to reduce radiation exposure to critical organs. However, the feasibility of combinatorial radiation therapy (CRT) in prostate cancer patients with seminal vesicle invasion remains insufficiently investigated. The number of studies focusing on this problem is still extremely small.Objective of this study is to evaluate the efficacy and toxicity of radiation therapy combined with hormone therapy for prostate cancer with seminal vesicle invasion.Materials and methods. From April 2016 to April 2020, 52 patients with prostate cancer (cT3bN0) received CRT at the clinic of the A.F. Tsyb Medical Radiological Research Center. The median patient follow-up was 29.7 months (from 11.9 to 58.4 months). The mean age of patients was 65.7 years. The initial mean level of PSA was 28.7 ng/ml. Fifty (96.2 %) patients were given radiation therapy together with hormone therapy.Results. The tolerability of CRT appeared satisfactory. Grade I acute radiation-induced reactions of the urinary tract occurred in 13 (25 %) patients; grade II ones - in 2 (3.8 %) patients. Grade I acute radiation-induced reactions of the gastrointestinal tract occurred in 11 (21.5 %) patients; grade II ones - in 1 (1.9 %) patient. Grade I late complications of the urinary tract were noted in 4 (7.7 %) patients; grade II ones - in 2 (3.8 %) patients. Grade I late complications of the gastrointestinal tract were noted in 2 (3.8 %) patients; grade II ones - in 3 (5.8 %) patients.The three-year cancer-specific survival rate was 97 %; the overall survival rate was 83 %. Eight (15.4 %) patients showed prostate cancer progression. Five (9.6 %) patients experienced cancer recurrence in the form of distant bone metastases. In 1 (1.9 %) patient, disease recurrence was associated with involvement of regional lymphatic collectors and distant inguinal lymph node metastases. Local recurrence was noted in 1 (1.9 %) patient. One (1.9 %) patient developed loco-regional recurrence with distant metastasis to bones. The three-year recurrence-free survival rate was 75.6 %.Conclusion. Our study demonstrates that CRT is highly effective in prostate cancer (cT3bN0) treatment while having an acceptable level of complications.
Family rituals in postdivorce families: The role of family structure and relationship quality for parents' and stepparents' attendance at children's birthdays
Authors: Fang Christian , Poortman Anne-Rigt , Van der Lippe Tanja 
Published: February 2022

Objective: To investigate if divorced parents celebrate their children's birthdays with their respective ex-partner and current partner, and whether they do so "jointly" with both.
Background: Family rituals like birthday celebrations are important and meaningful events in people's lives, but little is known about who partakes in these in contemporary postdivorce families.
Method: We assessed whether divorced parents celebrated their child's birthday together with their ex-partner (i.e., the child’s other biological parent), current partner (i.e., the child’s stepparent), and jointly with both. Dutch Data (N=2,451) was analyzed using linear probability models.
Results: Most parents celebrated the child's birthday without the ex-partner, but with the current partner. One quarter celebrated with both. The ex-partners' presence was more likely when parents' and their current partners' relationship with the ex-partner was good; and less likely when parents had repartnered and when the ex-partners had sole custody or additional biological or stepchildren. The presence of the current partner was more likely in case of coresidence with the biological parent and when the ex-partner had a new partner; and less likely when the ex-partners had sole custody and when parents’ relationship with the ex-partners was good.
Conclusion: Child-related family rituals mostly involve the "new" stepparent rather than both biological parents. The effects of relationship quality, co-residence, repartnering, and having additional biological or stepchildren highlight the importance of (step)parents' willingness to interact with each other, structural opportunities for parent-child interactions, and parents’ shifting loyalties from their ex-partner to their new family.
The Development of a Work Stress Model for Air Traffic Controllers in Indonesia
Authors: Saleh Lalu Muhammad , Russeng Syamsiar S , Tadjuddin Istiana , Yanti Iva Hardi , Syafitri Nurul Mawaddah , Yusbud Mahfuddin , Rahmadani Yulianah 
Published: February 2022

The workload complexity experienced by and expected air traffic controllers (ATCs) causes psychological fatigue, engenders stressful conditions, and affects their quality of life. This study investigated the development of a model of psychological fatigue in ATCs in Indonesia, which affected their work stress levels and quality of life. This cross-sectional, three-month study focused on 185 ATCs randomly selected from six AirNavs based on strata. The results indicated a relationship between work duration (p = .033) and stress on ATCs; additionally, a relationship between work time and the opportunity to meet personal life needs (p = .007) was found. Feelings of tiredness among ATCs manifested as a ‘thirsty throat’ feeling, and in saturation measurements, no respondents had experienced hypoxia in the two months of observation. Structural equation modeling showed that psychological fatigue had no direct effect on the quality of life; however, it had an indirect and significant effect on work stress (p = .001). It can be concluded that the stress conditions experienced by the ATCs have a palpable effect on feelings of fatigue and quality of life.
Study on Dynamic Response of Blocking Structure and Debris Flow Impulsive Force considering Material Source Erosion
Authors: Li Bai-Long , Wang Chang-Ming , Li Yan-Ying 
Published: February 2022

Abstract
The erosion of debris flows on the material source will affect the movement and impact of the debris flow. This paper adopted the coupled SPH-DEM-FEM to establish a complex dynamic model of the particle-fluid-erosion-structure of the debris flow and to assess the impact of erosion and sedimentation and analyse the dynamic response of the retaining structure of the debris flow. The strain-softening model was adopted to simulate the transformation of the debris flow body from the solid state to the transition state and finally into the liquid state. The coupled numerical analysis completely reproduces the debris flow erosion test, fitting the debris flow shape and thickness profile well. The impact process of the debris flow, the impact height behind the retaining dam, the deposition thickness, and the debris flow dynamic response significantly influence both with and without considering the effects of erosion. The results of this study are similar to existing literature and data, with the numerical analysis being consistent with the physical simulation tests in the existing literature, verifying the applicability of the SPH-DEM-FEM coupling analysis for assessing the debris flow impact retaining structures of erosion and sedimentation. The study also found that the dynamic response considering the debris flow impact and the retaining structures of erosion and sedimentation is more pronounced than when not considering erosion and sedimentation. Coupled numerical analysis can assess the potential effect of erosion and sedimentation, making a significant contribution to the assessment of the impact of debris flow and the design of retaining structures.
Crustal Structure beneath the Precambrian Cratons of Gondwanaland and Its Evolution Using Teleseismic Receiver Function
Authors: Mukherjee Pousali , Borah Kajaljyoti , Yadav Alok 
Published: February 2022

Abstract
The Gondwana supercontinent was an accretion of several cratons from different landmasses, namely South America, Antarctica, Africa, Madagascar, Australia, and the Indian subcontinent. The splitting of Gondwanaland during the Mesozoic led to the gradual rifting of these different cratons over geologic time. In this study, crustal structures are imaged by modeling receiver functions to understand the differences in the nature of the crust that was once part of Precambrian Gondwanaland. On comparing the overall crustal thickness with the age of the cratons, it was found that average bounds of crustal thickness varied from ~33 to 45 km in the Precambrian cratons of different ages, and composition varied from felsic to intermediate (Vp/Vs≈1.65−1.78). Observations of gradational Moho beneath few stations could indicate the possibility of mafic underplating at some point in their history of formation, growth, or evolution. Even if plate tectonics were dominant in the middle to late Archean, difference in spreading, drifting velocity, and distance travelled by the continents after Gondwana separation possibly led to crustal delamination, and destruction of thick crustal roots of cratons. Other than delamination, the role of episodic cycles of crustal growth is also observed in the pattern of crustal thickness across each division of the Precambrian. This could be due to alternative high and low crustal regeneration process, repeated episodic recycling, and reworking of early crust, supported by previous geodynamical models.
A New Mechanistic Model for Mineral Crystallization and Inhibition Kinetics and Its Application to Celestite
Authors: Zhao Yue , Dai Zhaoyi , Wang Xin , Dai Chong , Paudyal Samridhdi , Ko Saebom , Kan Amy T. , Tomson Mason 
Published: February 2022

Summary
Scale inhibitors are frequently used to control the mineral scale formations during industrial processes. However, few kinetic models with a mechanistic understanding of the inhibition mechanism have been developed. In this study, a new mechanistic model is developed to predict the kinetics of the mineral scale crystallization with and without inhibitors. In this new model, it is proposed that the inhibitors can adsorb on the nucleus surfaces following a Langmuir type isotherm and increase the nucleus interfacial energy, resulting in the prolongation of the induction time. The new model is applied to predict the crystallization and inhibition kinetics of celestite, which has been observed more frequently during various industrial processes with few quantitative models developed. The predicted induction times show close agreement with the experimental data produced in this study. Moreover, the fitted Langmuir-type adsorption reaction constant KL between celestite and the three inhibitors is comparable with the reported KL values in the previous studies, implying the reliability of the proposed inhibition mechanism of this new model. This new mechanistic model could be widely adopted in various disciplines, such as elucidation of the inhibition mechanisms, predicting the minimum inhibitor concentration, or new scale inhibitors design guidance, to mention a few.
Small-Sample Production Prediction of Fractured Wells Using Multitask Learning
Authors: Li Xuechen , Ma Xinfang , Xiao Fengchao , Xiao Cong , Wang Fei , Zhang Shicheng 
Published: February 2022

Summary
Domestic and foreign scholars have conducted extensive research on applying machine learning to post-fracture production prediction in recent decades and made great achievements in Bakken, Eagle Ford, Marcellus, and other large-scale oil and gas fields. However, few studies focus on small-sample production prediction of fractured wells, which is urgently needed in small-scale and newly developed reservoirs. In this work, we propose a novel small-sample production prediction framework based on multitask learning (MTL), including multitype data collection, task selection, data preprocessing, model training, and multitask production prediction. As for the trained model, feature extraction is first used through the deep hybrid network (DHN) by fully leveraging available multitype data such as numerical, sequence, and image. Then a multitask module based on the cross-stitch network (CSN) is integrated to automatically determine the information sharing degree of multiple production prediction tasks. In this way, data augmentation and model regularization are indirectly realized to handle the overfitting problem caused by insufficient training data. Finally, the proposed framework is applied to a small-sample field case with 59 fractured horizontal wells in northwest China. The comparison results show that the developed MTL-based model performs better than traditional single-task models in both prediction accuracy and learning efficiency. It provides an accurate and efficient tool for small-sample production prediction and can be used for reference to other small-sample domains in the petroleum industry.
Analogy between Vertical Upward Cap Bubble and Horizontal Plug Flow
Authors: Arabi Abderraouf , Saidj Faiza , Al-Sarkhi Abdelsalam , Azzi Abdelwahid 
Published: February 2022

SummaryThe intermittent gas-liquid flow can be seen in both vertical upward and horizontal pipes. In a vertical pipe, the gas pockets of intermittent flow can be present as cap bubbles (cap bubble flow) or Taylor bubbles (slug flow), while in a horizontal configuration, the intermittent flow can be as plug or slug flows. Extensive literature survey has shown a lack of deep understanding of the difference between the vertical upward cap bubble and horizontal plug flow regimes.This paper explains the hydrodynamic similarities between vertical cap bubble flow and horizontal plug flow regimes. Moreover, the differences between the cap bubble and slug flow in vertical pipes are explained in detail. The study was carried out using a collected database from the open literature of different flow parameters. A comparison between the behavior of the void fraction, bubble structure velocity, slippage number, slug frequency, and slug length demonstrated the similarity between cap bubble and plug flows. It was also demonstrated, from the evolution of the void fraction, that the gas-to-liquid superficial velocities ratio plays a significant role in the cap bubble-to-slug flow transition. These results highlight the existence of an analogy between vertical cap bubble and horizontal plug flow. In addition, the difference between the flow structures and flow parameters behavior between cap bubble and slug flow, demonstrated in this study, highlights the need to differentiate between the two flow patterns.
A Novel Design of Heterojunction Double Ferroelectric MOSFET (HDF-MOSFET) with Steep Subthreshold Slope and High Ion/Ioff Current Ratio
Authors: SANI MOJTABA HOSSEIN ZADEH , Li Shujuan 
Published: February 2022

Abstract
In this work, three novel structures using ferroelectric material are designed and simulated. The proposed structures are Improved Priority, Single Ferro (SF-MOSFET), Double Ferro (DF-MOSFET), and Heterojunction Double Ferro (HDF-MOSFET), respectively. Unlike other structures, these structures have a contact gate and two ferroelectric layers, and an insulation layer between these layers. HfO2 is used instead of the common perovskite ferroelectric layers such as zirconium lead titanate (PbZrTiO3) and strontium bismuth tantalum (SrBi2Ta2O9), which makes it compatible with the CMOS process as well as the scalability of the device. Ferroelectric layers, Insulation and Ferroelectric layers are stacked (F-I-F). Placing double ferro layers in the form of a stack increases the polarization effects and improves the application of the structure in memory. The memory performance can be saved even after the power is turned off and the readout properties are not destructive for double ferroelectric stack. perovskite Lead Zirconium Titan ate (PZT) is chosen as the ferroelectric materials. The DF-MOSFET structure, value of on-state current Ion=10−2, off-state current Ioff=10−15, and memory Windows MW=0.9V for memory applications. In the barrier layer of HDF-MOSFET structure, from composite materials that have used TiO2=60% and HfO2=40%, the amount of Ion=10−4.8, Ioff=10−35.2 and Ion/Ioff = 2.51×1035 is obtained, which is a suitable application for high frequency.
Energy-Efficient Routing Protocol For Enhancing The Vehicular Ad-Hoc Network Communication
Authors: Ali Zainab Hassan , Ali Hesham Arafat 
Published: February 2022

Abstract
Vehicular Ad-hoc Networks (VANET) have been significantly expanding to perform automotive services related to enhancing road networks, congestion flow, and even real-time traffic jams. Amid modern transportation systems, traffic quality has been relied on exchanging massive amounts of up-to-date information about their physical position and status with traffic management centers; this yields what’s called the ”data dissemination” problem. This type of phenomenon allows data propagation in a collaboratively and efficient manner to boost realtime performance. However, it brings several limitations in bandwidth usage and power consumption resulting in the premature end of network lifetime, as well as continuous break in path connection leading to lack of communication reliability and increasing packet loss probability. As a result, adjusting the rate of data dissemination over the network has become inescapable. The main objective of this study is to present a vehicle system design methodology that has the potential to achieve sufficient energy conservation as well as overcome real-time constraints. A dynamic real-time interaction architecture for vehicular networks based on an energy-efficient and QoS-aware routing technique and effective path estimation allowing for control of excessive dissemination of data traffic across the vehicular networks is proposed. The proposed architecture is also subjecting a new integration model between Software-Define Network (SDN) and fog computing for enhancing VANET performance. The simulation results show that the proposed architecture introduced an accurately controlling methodology in the transmission rate of data packets of VANET. There is a 60%-70% enhancement of the whole power consumption and network throughput, depending on the implementation of the proposed geographical routing methodology. The overall performance is enhanced in terms of packet delivery ratio, packet loss ratio, end-to-end delay time, and routing overhead.
Sturgeons In Large Rivers: Detecting The Near-Extinct Needles In A Haystack Via Edna Metabarcoding From Water Samples
Authors: Meulenbroek Paul , Hein Thomas , Friedrich Thomas , Valentini Alice , Tibor Eros , Schabuss Michael , Zornig Horst , Lenhardt Mirjana , Pekarik Ladislav , Jean Pauline , Dejean Tony , Pont Didier 
Published: February 2022

Abstract
Sturgeon populations are declining worldwide and are the target of extensive conservation efforts. Addressed in several pieces of legislation, sturgeons have received considerable attention as flagship or umbrella species. Despite the need for a better understanding of the distribution and population status, the use of traditional sampling methods failed in the past, thereby hampering reliable assessments, a prerequisite for conservation. Here, we describe the development and application of an environmental DNA (eDNA) metabarcoding approach for detecting rare sturgeons in large rivers. Exemplarily, we developed a reference database for five native Danube sturgeons (Acipenser stellatus, Acipenser gueldenstaedtii, Acipenser ruthenus, Acipenser nudiventris, and Huso huso) and two non-native species (Acipenser baerii and Acipenser transmontanus), assessed these ex situ, and used eDNA as a detection tool along the entire length of the Danube (Europe, ~2850 km) and major tributaries. In ex situ analyses, all assays yielded positive amplifications for the assessed sturgeon species. In the Danube, the presence of A. ruthenus was confirmed at 14 of 29 sites (48.3%), and in 2 of 18 tributary sites (11.1%), providing the first comprehensive large-scale biogeographical snapshot of this species. Relative species abundance varied between 0% and 2.5%, with sites registering positive detections being clustered in 3 sections of the Danube. Our findings enabled us to confirm the advantages of eDNA monitoring over traditional sampling methods and therefore we consider it to be a promising approach for application in conservation measures, fisheries management, scientific studies, and adaptive management plans for sturgeons on a global scale.
A Hybrid Tuned Mass Damper for Response Mitigation of Offshore Platforms
Authors: Cao Quoc Huong 
Published: February 2022

Abstract
A new hybrid type of the Tuned Mass Damper (HTMD), which consists of a Tuned Liquid Column Damper (TLCD) fixed on the top of a traditional Tuned Mass Damper (TMD), is developed for vibration control of an offshore platform. The results obtained from the parametric investigation show that the mass ratio between TLCD and TMD significantly affects the HTMD's performance. To assess the effectiveness and robustness of HTMD, extensive comparisons are made between an optimized HTMD and an optimum TMD with the same weight as the HTMD. The numerical computations indicate that the proposed HTMD offers a higher level of effectiveness in suppressing structural vibrations compared with a traditional TMD. However, the optimum HTMD is not robust in resisting the variation of the structural stiffness.
Effect of llama (Lama glama) manure and Trichoderma strain T1R3 on arsenic uptake by Swiss chard and broad bean crops. A strategy to minimize health risks
Authors: Yañez Luciano Matias , Alfaro Jimena Agustina , Carreras Natalia Maria Elisa Ávila , Mitre Graciela Bovi 
Published: February 2022

Abstract
The town of Pastos Chicos (Jujuy-Argentina), presents arsenic (As) concentrations in soil (49 mgAs kg−1) and water (1.44 mgAs L−1) significantly above the maximum allowable limits set by National Laws No 24,585 and N° 24,051. This study aimed to evaluate the effect of llama manure (Lama glama) and Trichoderma strain T1R3 on As uptake and toxicity in Swiss chard (Beta vulgaris var. cicla) and broad bean (Vicia faba L.) crops, while assessing potential human health risks. Results indicated that Trichoderma strain T1R3 inoculation stimulated broad bean plant growth by reducing As stress. Swiss chard crops treated with 5% manure and a manure/Trichoderma T1R3 combination reduced As absorption from 32.46 to 64.02% in roots, and from 35.2 to 44.5% in leaves. Broad bean crops inoculated with Trichoderma T1R3 showed a significant mitigation of toxicant accumulation in the leaves (67.42%). Also, the manure/Trichoderma T1R3 combination reduced As accumulation (57.46%) in broad bean roots. The efficacy of llama manure and of the llama manure/Trichoderma T1R3 combination in reducing health hazards that derive from As intake by consuming chard leaves was also reflected in Hazard Quotient < 1 values. Although Cancer Risk values decreased considerably, these showed there was a considerable carcinogenic risk for humans consuming chard leaves. These observations reveal that adding llama manure and Trichoderma T1R3 might mitigate As uptake by crops, thus reducing human health risks. This study advanced our understanding the complex llama manure/Trichoderma strain interactions in As-contaminated soils, which are imperative for developing the effective mitigations strategies.