bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advanced natural hydrated iron-alum oxides cation exchange resin for simultaneous phosphate and hardness removal
Authors: Tran Le Ba , Nguyen Trung Thanh , Padungthon Surapol , Le Tri Thich , Nguyen Thi Quynh Anh , Nguyen Nhat Huy 
Published: September 2022

AbstractIn this study, a hydrated iron-alum oxides-contained cation exchange resin (HIAO/225H) was synthesized for the first time from natural alum-ferric water of acid sulfate soil to improve the water quality. The HIAO/225H material was then characterized by FTIR, XRD, SEM, and EDX-mapping techniques and applied for phosphate and hardness removal tests. The phosphate removal by the HIAO/225H material reached equilibrium after 50 h with the highest adsorption capacity of 2.075 mg P g−1 (e.g., 69.16 mg P g−1 Fe) at pH 6, which was 1.12, 11.15, and 2.11 times higher than by hydrated ferric oxide/225H material, anion exchange resin (Akualite A420), and amphoteric ion exchange resin (MB6SR), respectively, under the same experimental conditions. The reason for the higher phosphate adsorption efficiency of HIAO/225H than the hydrated ferric oxide/225H material may be that HIAO contains Ca, Mg, and Al elements, leading to an easy formation of FeOOH on the surface. Particularly, HIAO/225H material was also effective for both hardness and phosphate removal with an adsorption capacity of 15.6 mg Ca g−1, 9.4 mg Mg g−1, and 1.825 mg P g−1, which is higher 1.2 times than the phosphate removal only. This may be due to co-precipitation to form Ca3(PO4)2 and Mg3(PO4)2 with the support of cation exchange resins. These results showed that the HIAO/225H material has a good performance in removing both phosphate and hardness, which could be applied in practical water and advanced wastewater treatment.
Cell wall synthesis and remodelling dynamics determine division site architecture and cell shape in Escherichia coli
Authors: Navarro Paula P. , Vettiger Andrea , Ananda Virly Y. , Llopis Paula Montero , Allolio Christoph , Bernhardt Thomas G. , Chao Luke H. 
Published: September 2022

AbstractThe bacterial division apparatus catalyses the synthesis and remodelling of septal peptidoglycan (sPG) to build the cell wall layer that fortifies the daughter cell poles. Understanding of this essential process has been limited by the lack of native three-dimensional views of developing septa. Here, we apply state-of-the-art cryogenic electron tomography (cryo-ET) and fluorescence microscopy to visualize the division site architecture and sPG biogenesis dynamics of the Gram-negative bacterium Escherichia coli. We identify a wedge-like sPG structure that fortifies the ingrowing septum. Experiments with strains defective in sPG biogenesis revealed that the septal architecture and mode of division can be modified to more closely resemble that of other Gram-negative (Caulobacter crescentus) or Gram-positive (Staphylococcus aureus) bacteria, suggesting that a conserved mechanism underlies the formation of different septal morphologies. Finally, analysis of mutants impaired in amidase activation (ΔenvC ΔnlpD) showed that cell wall remodelling affects the placement and stability of the cytokinetic ring. Taken together, our results support a model in which competition between the cell elongation and division machineries determines the shape of cell constrictions and the poles they form. They also highlight how the activity of the division system can be modulated to help generate the diverse array of shapes observed in the bacterial domain.
Effects of sediment flushing operations versus natural floods on Chinook salmon survival
Authors: Panthi Manisha , Lee Aaron A. , Dahal Sudesh , Omer Amgad , Franca Mário J. , Crosato Alessandra 
Published: September 2022

AbstractFlushing is a common measure to manage and reduce the amount of sediment stored in reservoirs. However, the sudden release of large volumes of sediment abruptly increases the suspended solids concentration and alters the riverbed composition. Similar effects can be produced also by natural flood events. Do flushing operations have more detrimental impacts than natural floods? To answer this question, we investigated the impact of flushing on the survival of the Chinook salmon (Oncorhynchus tshawytscha) in the Sandy River (OR, USA), assuming that sediment is flushed from hypothetical bottom gates of the, now decommissioned, Marmot Dam. The effects of several flushing scenarios are analyzed with a 2D morphodynamic model, together with habitat suitability curves and stress indicators. The results show that attention has to be paid to duration: the shorter the flushing operation, the lesser the stresses on fish survival and spawning habitats. Flushing causes high stress to salmon eggs and larvae, due to unbearable levels of suspended sediment concentrations. It also decreases the areas usable for spawning due to fine-sediment deposition, with up to 95% loss at peak flow. Without the dam, the corresponding natural flood event would produce similar effects, with up to 93% loss. The study shows that well-planned flushing operations could mimic a natural impact, but only partly. In the long-term, larger losses of spawning grounds can be expected, since the removal of fine sediment with the release of clear water from the reservoir is a lengthy process that may be undesirable due to water storage reduction.
Prevalence and determinants of return to work after various coronary events: meta-analysis of prospective studies
Authors: Kai Samantha Huo Yung , Ferrières Jean , Rossignol Mélisande , Bouisset Frédéric , Herry Julie , Esquirol Yolande 
Published: September 2022

AbstractReturn to work (RTW) after a coronary event remains a major concern. This systematic review and meta-analysis of prospective studies published between January 1988 and August 2020, aim to evaluate the prevalence of RTW after a coronary event (myocardial infarction, acute coronary syndrome, angina pectoris) and to assess the determinants of RTW (such as follow-up duration, date of recruitment, country, gender, occupational factors, etc.). PRISMA and MOOSE guidelines were followed. Study quality was assessed using the Newcastle–Ottawa Scale. Random-effects models were carried out to determine pooled prevalence estimates and 95% confident interval. A total of 43 prospective studies (34,964 patients) were investigated. RTW overall random effects pooled prevalence was estimated at 81.1% [95% CI 75.8–85.8]. Country, year of implementation or gender did not significantly modify the prevalence estimates. Lower level of education and degraded left ventricular ejection fraction decreased RTW prevalence estimates (respectively, 76.1% vs 85.6% and 65.3% vs 77.8%). RTW prevalence estimates were higher for white-collars (81.2% vs 65.0% for blue-collars) and people with low physical workload (78.3% vs 64.1% for elevated physical workload).Occupational physical constraints seem to have a negative role in RTW while psycho-logical factors at work are insufficiently investigated. A better understanding of the real-life working conditions influencing RTW would be useful to maintain coronary patients in the labor market.
Comparison of adenoma detection in different colorectal segments between deep-sedated and unsedated colonoscopy
Authors: Sui Yue , Wang Qing , Chen Hai-Hua , Lu Jun-Hui , Wen Qing , Wang Zhen-Zhen , Wang Guan-Feng , Jia Hui , Xiao Tao , Wang Na-Ping , Hao Jun-Lian , Zhang Yi-Ping , Cao Feng-Zhen , Wu Xiao-Peng , Chen Xing 
Published: September 2022

AbstractTo investigate if deep-sedated colonoscopy affects adenoma detection in certain colorectal segment. Review of colonoscopy reports, electronic images and medical records of individuals underwent screening colonoscopy with or without propofol sedation between October 2020 and March 2021 from seven hospitals in China. A total of 4500 individuals were analyzed. There was no significant difference in ADR between deep-sedated colonoscopy and unsedated colonoscopy [45.4% vs. 46.3%, P > 0.05]. The APP of deep-sedated colonoscopy was lower than unsedated colonoscopy (1.76 ± 0.81 vs. 2.00 ± 1.30, P < 0.05). Both average number of adenomas and luminal distention score of splenic flexure and descending colon were lower in deep-sedated colonoscopy (P < 0.05), and average number of adenomas was positively correlated with an improved distension score in splenic flexure and descending colon (splenic flexure r = 0.031, P < 0.05; descending colon r = 0.312, P < 0.05). Linear regression model showed deep-sedated colonoscopy significantly affected luminal distention of splenic flexure and descending colon as well as average number of adenomas detected in splenic flexure (P < 0.05). Deep-sedated colonoscopy decreased adenoma detection in splenic flexure and the luminal distention of splenic flexure and descending colon compared with unsedated colonoscopy.
Comparative removal of hazardous cationic dyes by MOF-5 and modified graphene oxide
Authors: Mohammadi Ali Akbar , Moghanlo Soheila , Kazemi Malihe Samadi , Nazari Shahram , Ghadiri Seid Kamal , Saleh Hossein Najafi , Sillanpää Mika 
Published: September 2022

AbstractAmong cationic dyes, malachite green (MG) is commonly used for dying purposes and also as an inhibitor in aquaculture, food, health, and chemical industries due to its cytotoxic effects. Therefore, MG removal is essential to keep the ecosystem and human health safety. Adsorption is a viable and versatile option and exploring efficient adsorbents have high priority. Herein, MOF-5 and aminated corn Stover reduced graphene oxide (ACS-RGO) of typical adsorbents of metal–organic-frameworks (MOFs) and carbon-based classes were studied for MG removal. MOF-5 and ACS-RGO had a specific surface area and total pore volume of 507.4 and 389.0 m2/g, and 0.271 cm3/g and 0.273 cm3/g, respectively. ACS-RGO was superior for MG adsorption and the kinetic rate coefficient for ACS-RGO was ~ 7.2 times compared to MOF-5. For ACS-RGO, MG removal remained high (> 94%) in a wide range of pH. However, dye removal was pH-dependent for MOF-5 and increased from ~ 32% to ~ 67% by increasing pH from 4 to 12. Increasing dye concentration from 25 mg/L to 100 mg/L decreased adsorption by MOF-5 and ACS-RGO for ~ 30% and 7%, respectively. Dye removal was evident in a few tens of seconds after adding ACS-RGO at doses above 0.5 g/L. A significant loss of 46% in adsorption was observed by decreasing MOF-5 mass from 1 to 0.1 g/L. ACS-RGO removed MG in multilayer with an exceptional adsorption capacity of 1088.27 mg/g. In conclusion, ACS-RGO, and MOF-5 showed promising kinetic rates and adsorption capacities toward MG.
The effect of time regime in noise exposure on the auditory system and behavioural stress in the zebrafish
Authors: Wong Man Ieng , Lau Ieng Hou , Gordillo-Martinez Flora , Vasconcelos Raquel O. 
Published: September 2022

AbstractAnthropogenic noise of variable temporal patterns is increasing in aquatic environments, causing physiological stress and sensory impairment. However, scarce information exists on exposure effects to continuous versus intermittent disturbances, which is critical for noise sustainable management. We tested the effects of different noise regimes on the auditory system and behaviour in the zebrafish (Danio rerio). Adult zebrafish were exposed for 24 h to either white noise (150 ± 10 dB re 1 μPa) or silent control. Acoustic playbacks varied in temporal patterns—continuous, fast and slow regular intermittent, and irregular intermittent. Auditory sensitivity was assessed with Auditory Evoked Potential recordings, revealing hearing loss and increased response latency in all noise-treated groups. The highest mean threshold shifts (c. 13 dB) were registered in continuous and fast intermittent treatments, and no differences were found between regular and irregular regimes. Inner ear saccule did not reveal significant hair cell loss but showed a decrease in presynaptic Ribeye b protein especially after continuous exposure. Behavioural assessment using the standardized Novel Tank Diving assay showed that all noise-treated fish spent > 98% time in the bottom within the first minute compared to 82% in control, indicating noise-induced anxiety/stress. We provide first data on how different noise time regimes impact a reference fish model, suggesting that overall acoustic energy is more important than regularity when predicting noise effects.
Simple diagnosis of cancer by detecting CEA and CYFRA 21-1 in saliva using electronic sensors
Authors: Joshi Sowmya , Kallappa Shashidhar , Kumar Pranjal , Shukla Sudhanshu , Ghosh Ruma 
Published: September 2022

AbstractOne way of early diagnosis of cancer is by detecting the biomarkers that get introduced into easily accessible body fluids. We report the development of portable and rapid electronic biosensors for quantitative detection of two secretive cancer biomarkers–Carcinoembryonic antigen (CEA) and Cytokeratin fragment 19 (CYFRA 21-1). The reduced graphene oxide (rGO)/ melamine (MEL)/antibodies/ bovine serum albumin (BSA) based devices were tested for 1 pg/mL to 800 ng/mL of CEA and CYFRA 21-1. The responses of the sensors ranged from 7.14 to 59.1% and from 6.18 to 64% for 1 pg/mL to 800 ng/mL CEA and CYFRA 21-1 respectively. A read-out circuit was assembled to develop a portable prototype which was used to assess the concentrations of the two antigens present in saliva samples of 14 subjects. The prototype could accurately discriminate between 9 oral squamous cell carcinoma patients and 5 healthy controls.
Reduction of the occlusion effect induced by earplugs using quasi perfect broadband absorption
Authors: Carillo Kévin , Sgard Franck , Dazel Olivier , Doutres Olivier 
Published: September 2022

AbstractPassive earplugs are used to prevent workers from noise-induced hearing loss. However, earplugs often induce an acoustic discomfort known as the occlusion effect. This phenomenon corresponds to an increased auditory perception of the bone-conducted part of physiological noises at low-frequency and is associated with the augmentation of the acoustic pressure in the occluded earcanal. In this work, we report a new concept of passive earplugs for mitigating the occlusion effect between 100 Hz and 1 kHz. The strategy consists in reducing the input impedance of the earplug seen from the earcanal by using quasi-perfect broadband absorbers derived from the field of meta-materials. The proposed “meta-earplug” is made of 4 critically coupled Helmholtz resonators arranged in parallel. Their geometry is optimized using an evolutionary algorithm associated with a theoretical model of the meta-earplug input impedance. The latter is validated against a finite-element approach and impedance sensor measurements. The meta-earplug is manufactured by 3D printing. Artificial test fixtures are used to assess the occlusion effect and the insertion loss. Results show that the meta-earplug induces an occlusion effect approximately 10 dB lower than foam and silicone earplugs while it provides an insertion loss similar to the silicone earplug up to 5 kHz.
Association of late-life body mass index with the risk of Alzheimer disease: a 10-year nationwide population-based cohort study
Authors: Cho Su Hwan , Jang Minseol , Ju Hyorim , Kang Min Ju , Yun Jae Moon , Yun Jae Won 
Published: September 2022

AbstractExisting data for the association between late-life body mass index (BMI) and the risk of Alzheimer’s disease (AD) in the underweight population are limited with conflicting results. A large population-based cohort study of 148,534 individuals aged ≥ 65 years who participated in the national health screening program from 2002 to 2005 was performed using the Korean National Health Insurance Service-Senior cohort database 2006–2015. The risk of AD according to BMI category (kg/m2) in Asians was evaluated using a multivariable Cox regression model, after adjustments for age, sex, lifestyle, low-income status, and comorbidities. To evaluate the association between BMI and AD risk, the underweight population was further subdivided according to the degree of thinness. During the 10-year follow-up period, 22,279 individuals developed AD. Relative to the normal-weight population, the estimated adjusted hazard ratio (HR) for incident AD in the underweight, overweight, and obese populations was 1.17 (95% confidence interval [CI], 1.09–1.24), 0.90 (0.87–0.93), and 0.83 (0.80–0.85), respectively. In the underweight population, AD risk increased as the degree of thinness increased (p for the trend, < .001). Late-life BMI showed a significant inverse relationship with AD risk, especially in the underweight population. Public health strategies to screen for AD more actively in the underweight population and improve their weight status may help reduce the burden of AD.
Comparison of educational performance between the only children and children in two-child families
Authors: Lao Yehui , Lin Suxu 
Published: September 2022

AbstractThis paper estimates the causal effect of only-child status on educational performance among junior high school students from only-child and two-child families in China. It uses the dataset of the China Education Panel Survey 2013–14. The results show that the only children's educational outcomes are significantly low than students from two-child families. Only children's willpower and extraversion are weaker than children's from two-child families. The scale economies effect is strong and the resource dilution effect is weak when sibling size is small.
Effect assessment for the interaction between shaking table and eccentric load
Authors: Wang Juke , Liu Aiwen , Li Xiaojun , Zhou Zhenghua , Chen Su , Ji Jinbao 
Published: September 2022

AbstractElectro-hydraulic shaking table is an essential experimental apparatus to evaluate structural performance under actual vibration condition. The control-structure interaction (CSI) between shaking table and eccentric load has lately received considerable attention for causing the accuracy degradation of shaking table test. At present, the research gap of the influence of the eccentricity of load on the CSI makes it challenging to find the CSI effects. And an effect assessment is yet to be proposed to evaluate the CSI effects, which has impeded the development of test technology. To overcome those theoretical bottlenecks, in this research, an analytical transfer function matrix of shaking table and eccentric load is established to analyze the CSI effects. The analysis is conducted under such conditions as different mass ratio (MR), moment of inertia ratio (IR), and eccentric distance ratio (ER) conditions. Through the analysis, the role of the ER is identified, the sensitivities of the MR, IR, and ER to the transfer function matrix are revealed, and the CSI effects are found. Furthermore, a novelty effect assessment is proposed to appraise whether the CSI effects can be ignored in shaking table test. And the visualization expression of the effect assessment is obtained for convenient application.
Three-dimensional control of alluvial fans by rock uplift in an extensional regime: Aydın Range, Aegean extensional province
Authors: Özpolat Emrah , Yıldırım Cengiz , Görüm Tolga , Gosse John C. , Şahiner Eren , Sarıkaya M. Akif , Owen Lewis A. 
Published: September 2022

AbstractTectonics imparts a first-order control on the overall morphology of alluvial fan systems in extensional settings by influencing sediment flux and accommodation space, while other factors such as climate, catchment lithology, and fault footwall characteristics are secondary. Previous alluvial fan modeling studies have focused on the link between the three-dimensional development of alluvial fans and rock uplift, however, despite the potential influence of tectonics on the overall three-dimensional morphology of alluvial fans, the controlling mechanisms, as well as their relative importance, remain largely unquantified in a natural setting with a targeted source-to-sink approach. Here, we examine 45 alluvial fans and their catchments along the southern mountain front of the Aydın Range, delimited by segmented normal faults in the western Anatolia Extensional Province, to quantify the role of rock uplift. We quantify river incision rates and catchment-wide erosion rates together with a series of topographic analyses across the southern flank of the Aydın Range as a proxy for rock uplift. Our results indicate that the spatial distribution of thicker and steeper alluvial fans fit well with higher rock uplift rates along the strike of the mountain front. In contrast, a lower uplift rate is responsible for prograding alluvial fans with decreasing thickness and gradients. Also, our data shows that alluvial fan thickness compared to other alluvial fan metrics strongly associated with the pattern of the rock uplift. This study demonstrates a field-based, quantitative linkage between three-dimensional alluvial fan morphology and rock uplift which has significant implications for improving alluvial fan models and understanding how alluvial fans respond to tectonics in extensional regions.
Independent phenotypic plasticity axes define distinct obesity sub-types
Authors: Yang Chih-Hsiang , Fagnocchi Luca , Apostle Stefanos , Wegert Vanessa , Casaní-Galdón Salvador , Landgraf Kathrin , Panzeri Ilaria , Dror Erez , Heyne Steffen , Wörpel Till , Chandler Darrell P. , Lu Di , Yang Tao , Gibbons Elizabeth , Guerreiro Rita , Bras Jose , Thomasen Martin , Grunnet Louise G. , Vaag Allan A. , Gillberg Linn , Grundberg Elin , Conesa Ana , Körner Antje ,   PERMUTE, Triche Timothy , Lempradl Adelheid , DeBruine Zachary J. , Wolfrum Emily , Madaj Zachary , Gruber Tim , Grimaldi Brooke , Parham Andrea , McDonald Mitchell J. , Nadeau Joseph H. , Polyak Ildiko , Khoo Carmen , Lary Christine , Gluckman Peter D. , Karnani Neerja , Carey David , Loos Ruth J. F. , Seifert Gabriel , Pospisilik J. Andrew 
Published: September 2022

AbstractStudies in genetically ‘identical’ individuals indicate that as much as 50% of complex trait variation cannot be traced to genetics or to the environment. The mechanisms that generate this ‘unexplained’ phenotypic variation (UPV) remain largely unknown. Here, we identify neuronatin (NNAT) as a conserved factor that buffers against UPV. We find that Nnat deficiency in isogenic mice triggers the emergence of a bi-stable polyphenism, where littermates emerge into adulthood either ‘normal’ or ‘overgrown’. Mechanistically, this is mediated by an insulin-dependent overgrowth that arises from histone deacetylase (HDAC)-dependent β-cell hyperproliferation. A multi-dimensional analysis of monozygotic twin discordance reveals the existence of two patterns of human UPV, one of which (Type B) phenocopies the NNAT-buffered polyphenism identified in mice. Specifically, Type-B monozygotic co-twins exhibit coordinated increases in fat and lean mass across the body; decreased NNAT expression; increased HDAC-responsive gene signatures; and clinical outcomes linked to insulinemia. Critically, the Type-B UPV signature stratifies both childhood and adult cohorts into four metabolic states, including two phenotypically and molecularly distinct types of obesity.