bluuebunny/crossref_metadata_2025_split huggingface dataset:
The intention to get COVID-19 vaccine and vaccine uptake among cancer patients: An extension of the theory of planned behaviour (TPB)
Authors: Servidio Rocco , Malvaso Antonio , Vizza Deborah , Valente Moira , Campagna Maria Rosita , Iacono Melania Lo , Martin Leslie R. , Bruno Francesco 
Published: June 2022

AbstractThe psychosocial impact of coronavirus disease 2019 (COVID-19) on human life is well-known. Although vaccine protection represents an effective way to control the spread of the virus, vaccination hesitancy may decrease individuals’ willingness to get vaccinated, including among cancer patients. Therefore, the objective of the current study was to examine the predictors of cancer patients’ intentions to receive COVID-19 vaccinations and vaccine uptake, using and integrating the theory of planned behaviour (TPB) and the health belief model (HBM). A sample of 276 Italian cancer patients (54% female and 46% male) ranging from 19 to 85 years (M = 49.64, SD = 11.53) was recruited by administering an online questionnaire. The current study results showed that cancer patients with higher trust in health authorities tended to have vaccine-positive subjective norms, perceived that vaccination was under their control, and viewed COVID-19 vaccines positively. On the other hand, the perceived risk of COVID-19 was related to subjective norms but not to perceived behavioural control or attitudes towards COVID-19 vaccination. The current study reveals that TPB variables can function effectively as mediators between perceived risk, trust, and intention to vaccinate but at different levels. Together, these findings suggest that effective interventions (both public health messaging and personal medical communications) should focus on enhancing trust in health authorities, while at the same time endeavouring to highlight subjective norms that are vaccine-positive.
Mechanical Characterization and Creep Behavior of a Stone Heritage Material Used in Granada (Spain): Santa Pudia Calcarenite
Authors: Gil-Martín Luisa María , Fernández-Ruiz Manuel Alejandro , Hernández-Montes Enrique 
Published: June 2022

AbstractSanta Pudia calcarenite was one of the most commonly used building materials in the construction of historical buildings in the city of Granada (Spain). As a result, Santa Pudia calcarenite has been mainly studied from a petrographical point of view in previous works. In this work, the mechanical properties of Santa Pudia calcarenite are studied. The main mechanical properties (compressive strength, elastic modulus and Poisson’s ratio) were determined using the corresponding tests. Samples of Santa Pudia calcarenite were heated at 550 °C to study the effect of high temperatures on its compressive strength. Two different cooling methods were considered: air-cooling and water-cooling. Stress–strain curves of heated and non-heated samples were obtained from uniaxial compression tests. Creep is of great importance in the long-term structural assessment of historical buildings. To study the creep behaviour of Santa Pudia calcarenite, samples were subjected to uniaxial compressive tests at constant stress until the stabilization of the recorded strains was reached. Different rheological models were adjusted to the experimental results to simulate the long-term behaviour of the material studied. The instantaneous response to additional loadings on the samples (maintaining the long-term loading and deformation) were also studied. Results show that a Santa Pudia calcarenite specimen subjected to dead loads will suffer a higher instantaneous deformation against a sudden load than a non-preloaded specimen. This degradation effect can be particularly important in the case of a seismic evaluation of historical buildings.
Axial Performance of Cementitious Grouted Cable Bolts Under Rotation Constraint Scenarios
Authors: Rastegarmanesh Ashkan , Mirzaghorbanali Ali , McDougall Kevin , Aziz Naj , Anzanpour Sina , Nourizadeh Hadi , Moosavi Mahdi 
Published: June 2022

AbstractWith the increased use of cable bolts in mining and civil projects worldwide, it is important to understanding the performance of these support structures in different scenarios. The axial load transfer mechanisms of six cable bolts were investigated experimentally in this research study. A large-scale pull-out testing apparatus with a capacity of 1000 kN was designed and manufactured as part of the investigation. A common commercial cementitious grout with a uniaxial compressive strength of 60 MPa was used to encapsulate 300 mm length samples. Passive confinement encapsulated each sample to ensure the concrete’s integrity during the testing. The encapsulated cable bolts were then subjected to axial loads using a hydraulic ram, with the axial load and displacement measured using a load cell and LVDTs. Two scenarios were investigated: free rotation and restricted rotation. The results demonstrated that the apparatus effectively recorded the behaviour of the cable during pull-out and identified that the radial stiffness of the samples had a significant impact on the overall load of the system. The results also indicated that rotation had a limited influence on the load behaviour of the samples tested.
The effect of type of specialty (periodontology/oral surgery) on early implant failure: a retrospective “Big-Data” study from a nation-wide dental chain in Israel
Authors: Mordechai Findler , Tali Chackartchi , Jonathan Mann , Ori Platner , Yaron Bernstein , Ram Shefer , Guy Tobias 
Published: June 2022

Abstract

Objectives

To evaluate early implant failure rate of implants placed by maxillofacial-oral surgeons and periodontists.

Material and methods
A nested case-case study was performed to analyze treatment outcome of 27 oral surgeons and 30 periodontists who performed at least 100 dental implants between 2017 and 2019 in 54 clinics of “Maccabi-Dent,” a nation-wide dental chain. A total of 26,865 implants were evaluated.

Results
The early failure rate of 1.3% achieved by the periodontists was lower than the 1.7% early failure rate achieved by oral surgeons. Differences were not statistically different. Oral surgeons in the study cohort were insignificantly older in age, with more years of experience as dentists and as specialists. However, the only parameter found to be a predictor to early implant failure in a linear regression model was related to postgraduate training. Explicitly, the mean number of implants placed during specialty program. This number was higher for the periodontists and found to be significantly contributing predictor to early implant failure. Clinicians’ age and years of experience as dentists or as specialist were not found to be predictors to early implant failure rate.

Conclusions
No statistically significant differences were found in early implant failure rate between oral surgeons and periodontists. The number of implants placed during specialty program has a statistical predictive value to early implant failure rate.

Clinical relevance
Care and attention should be taken to re-evaluate clinical training in the field of implantology during specialty program. To optimize surgeons’ control on treatment outcome.
Incidence of fistula occurrence in patients with cervical cancer treated with bevacizumab: data from real-world clinical practice
Authors: Sugiyama Toru , Katsumata Noriyuki , Toita Takafumi , Ura Masako , Shimizu Ayaka , Kamijima Shuichi , Aoki Daisuke 
Published: June 2022

Abstract
Background
This study aimed to determine the incidence of pelvic fistulas in cervical cancer patients treated with bevacizumab in Japanese clinical practice.

Methods
A post-marketing surveillance (PMS) study was conducted between June 2016 and February 2018 to survey physicians who treated advanced or recurrent cervical cancer patients with bevacizumab (according to the product label). The clinical/treatment status of patients with pelvic fistulas was assessed in an additional retrospective case series study.

Results
142 patients were included in the PMS study (median age 51 years; 66.9% squamous cell carcinoma; 66.2% recurrent cervical cancer; 64.1% previous radiotherapy). Patients received a median of seven bevacizumab doses. Six patients, all of whom had a history of pelvic irradiation, developed seven fistulas (4.2%; 95% confidence interval, 1.56–8.96), and five patients had also undergone pelvic surgery. The case series study of the patients who developed fistulas indicated that three patients had high cumulative bladder and rectal doses of radiation, and two of them had undergone salvage re-irradiation for pelvic recurrence. The other three patients underwent both radical hysterectomy and adjuvant radiotherapy, but did not receive an excessive radiation dose to the bladder or rectum.

Conclusions
This study found that the upper limit of the 95% confidence interval for pelvic fistula incidence did not exceed the incidence reported in the GOG 240 study. To ensure an adequate benefit-risk assessment of bevacizumab in cervical cancer patients, a comprehensive evaluation of prior treatment is essential and the possibility of unexpected fistulas, even after careful evaluation, should be considered.
Clonal hematopoiesis is not prevalent in Hutchinson-Gilford progeria syndrome
Authors: Díez-Díez Miriam , Amorós-Pérez Marta , de la Barrera Jorge , Vázquez Enrique , Quintas Ana , Pascual-Figal Domingo A. , Dopazo Ana , Sánchez-Cabo Fátima , Kleinman Monica E. , Gordon Leslie B. , Fuster Valentín , Andrés Vicente , Fuster José J. 
Published: June 2022

Abstract
Clonal hematopoiesis of indeterminate potential (CHIP), defined as the presence of somatic mutations in cancer-related genes in blood cells in the absence of hematological cancer, has recently emerged as an important risk factor for several age-related conditions, especially cardiovascular disease. CHIP is strongly associated with normal aging, but its role in premature aging syndromes is unknown. Hutchinson-Gilford progeria syndrome (HGPS) is an ultra-rare genetic condition driven by the accumulation of a truncated form of the lamin A protein called progerin. HGPS patients exhibit several features of accelerated aging and typically die from cardiovascular complications in their early teens. Previous studies have shown normal hematological parameters in HGPS patients, except for elevated platelets, and low levels of lamin A expression in hematopoietic cells relative to other cell types in solid tissues, but the prevalence of CHIP in HGPS remains unexplored. To investigate the potential role of CHIP in HGPS, we performed high-sensitivity targeted sequencing of CHIP-related genes in blood DNA samples from a cohort of 47 HGPS patients. As a control, the same sequencing strategy was applied to blood DNA samples from middle-aged and elderly individuals, expected to exhibit a biological age and cardiovascular risk profile similar to HGPS patients. We found that CHIP is not prevalent in HGPS patients, in marked contrast to our observations in individuals who age normally. Thus, our study unveils a major difference between HGPS and normal aging and provides conclusive evidence that CHIP is not frequent in HGPS and, therefore, is unlikely to contribute to the pathophysiology of this accelerated aging syndrome.
Levothyroxine-induced serum free thyroxine response following radioactive iodine administration in patients thyroidectomized for differentiated thyroid cancer: A randomized controlled trial
Authors: Marina Michela , Maglietta Giuseppe , De Filpo Giuseppina , Aloe Rosalia , Gnocchi Cecilia , Iezzi Elisa , Caminiti Caterina , Ceresini Graziano 
Published: June 2022

Abstract
Purpose
Patients undergoing thyroidectomy for differentiated thyroid cancer (DTC) may require 131-radioactive iodine (RAI) administration for remnant ablation or disease treatment. After ingestion, RAI resides within the gastrointestinal tract potentially leading to mucosal damage and abnormalities in the absorption of levothyroxine (LT4). The aim of this study was to evaluate whether serum FT4 peak, induced by a LT4 challenge, changes according to the LT4 formulation (solid or liquid) in both RAI and non-RAI-treated DTC patients.

Methods
This was a monocentric controlled clinical trial, with a parallel two-groups (1:1) randomization of sequence of LT4 formulation. Patients received 200 mcg LT4 orally administered at 08:00 h, in both solid and liquid formulation, at one-week interval, at baseline and after 1, 3, and 6 months from RAI administration. At each time-point, circulating FT4 was evaluated both before LT4 assumption as well as after 1 and 3 h. FT4 increments were evaluated as area under the curve response (AUC). Analogous protocol with the same time-intervals was followed for non-RAI patients.

Results
The trial included 29 consecutive DTC patients, nineteen of whom were submitted to RAI. In RAI subjects, we observed an overall significant reduction in serum FT4 increments with the most relevant decrease at the 1-month time-point, (FT4 AUC: 4.46 ± 0.72 (M ± SD) vs 4.07 ± 0.63 in baseline vs 1-month, P = 0.001) without any difference between the two LT4 formulations. No difference in serum FT4 AUC was found in non-RAI subjects.

Conclusion
LT4-induced serum FT4 responses are reduced following RAI administration in thyroidectomized DTC patients.
Reduced efficacy of biocontrol agents and plant resistance inducers against potato early blight from greenhouse to field
Authors: Stridh Linnea J. , Mostafanezhad Hadis , Andersen Christian B. , Odilbekov Firuz , Grenville-Briggs Laura , Lankinen Åsa , Liljeroth Erland 
Published: June 2022

AbstractEarly blight in potato, caused by Alternaria solani, is mainly controlled by frequent applications of synthetic fungicides. Reducing the use of synthetic fungicides in agriculture is desired to reach an overall sustainable development since the active components can be harmful for humans and for the ecosystem. In integrated pest management, IPM, the idea is to combine various measures, including optimized crop management, crop rotation, use of resistant cultivars, biological control agents (BCAs), plant resistance inducers, and fertilizers, to decrease the dependence on traditional chemical fungicides. In this paper, we present the results from greenhouse and field trials where we evaluated the effect of strategies aimed at reducing our reliance on synthetic fungicides including treatments with biological control agents (BCAs) (Pythium oligandrum, Polygandron®, and Bacillus subtilis, Serenade®) and plant resistance inducers (silicon products HortiStar® and Actisil®) for early blight in potato. The agents were applied separately or in combination with each other or with synthetic fungicides. In the greenhouse, trials application of these agents resulted in 50–95% reduction of infection by A. solani, but their combination did not generally improve the outcome. However, the effects were much smaller in the hand-sprayed field trials, 20–25% disease reduction and almost disappeared in full-scale field trials where application was done with tractor sprayers. In this article, we discuss possible reasons behind the drop in efficacy from greenhouse trials to full-size field evaluation.
Classifying home care clients’ risk of unplanned hospitalization with the resident assessment instrument
Authors: Rönneikkö Jukka K. , Huhtala Heini , Finne-Soveri Harriet , Valvanne Jaakko N. , Jämsen Esa R. 
Published: June 2022

Abstract
Purpose
To identify predictive case finding tools for classifying the risk of unplanned hospitalization among home care clients utilizing the Resident Assessment Instrument-Home Care (RAI-HC), with special interest in the Detection of Indicators and Vulnerabilities for Emergency Room Trips (DIVERT) Scale.

Methods
A register-based, retrospective study based on the RAI-HC assessments of 3,091 home care clients (mean age 80.9 years) in the City of Tampere, Finland, linked with hospital discharge records. The outcome was an unplanned hospitalization within 180 days after RAI-HC assessment. The Area Under the Curve (AUC) and the sensitivity and specificity were determined for the RAI-HC scales: DIVERT, Activities of Daily Living Hierarchy (ADLh), Cognitive Performance Scale (CPS), Changes in Health, End-Stage Diseases, Signs, and Symptoms Scale (CHESS), and Method for Assigning Priority Levels (MAPLe).

Results
Altogether 3091 home care clients had a total of 7744 RAI-HC assessments, of which 1658 (21.4%) were followed by an unplanned hospitalization. The DIVERT Scale had an AUC of 0.62 (95% confidence interval 0.61–0.64) when all assessments were taken into account, but its value was poorer in the older age groups (< 70 years: 0.71 (0.65–0.77), 70–79 years: 0.66 (0.62–0.69), 80–89 years: 0.60 (0.58–0.62), ≥ 90 years: 0.59 (0.56–0.63)). AUCs for the other scales were poorer than those of DIVERT, with CHESS nearest to DIVERT. Time to hospitalization after assessment was shorter in higher DIVERT classes.

Conclusion
The DIVERT Scale offers an approach to predicting unplanned hospitalization, especially among younger home care clients. Clients scoring high in the DIVERT algorithm were at the greatest risk of unplanned hospitalization and more likely to experience the outcome earlier than others.
Second-class citizens? Subjective social status, acculturative stress, and immigrant well-being
Authors: Bernal Darren R. , Misiaszek Kimberly Ho , Ayala Johanna , Kenley Niki 
Published: June 2022

AbstractThe effects of social hierarchy on well-being are pervasive. An individual’s social status within the hierarchy has been proposed to play a role in acculturative stress and psychological well-being. Subjective social status is a method of measuring social status that has not been examined in immigrants’ well-being. In an attempt to fill this gap in the literature, this study explored questions about immigrants’ well-being as they deal with acculturative stressors in the United States. In particular, the potential role of subjective social status (SSS) in the acculturative stress process was examined. Three hundred and five adult immigrants from over 68 countries were recruited. Overall, the results indicated a negative association between acculturative stress with quality of life, psychological well-being, and physical health. Regression analysis also indicated that subjective social status moderated this negative association. The results make the contribution that SSS is relevant to the association of acculturative stress and immigrant well-being.
The electoral success of social media losers: a study on the usage and influence of Twitter in times of elections in Paraguay
Authors: Saldivar Jorge , Parra Cristhian , Laconich Mical , Cernuzzi Luca 
Published: June 2022

AbstractIn recent years, social media has become increasingly relevant in democratic decision-making processes, such as referendums or elections. Recent investigations have raised the concern of social media misuse in attempts to manipulate the public opinion and influence results, undermining the foundations of democracy. By analyzing the use of Twitter during the 2017/2018 presidential elections in Paraguay, this study provides empirical evidence and analysis about the role of social media on political campaigns. In a departure from other countries in the region, dominance in this network did not correlate with elections results. The results we highlight in this article, therefore, challenge the impact of social media on elections, offering an interesting view of their role in Latin America countries, like Paraguay.
Students’ views on what aids their learning of school science in Lagos state, Nigeria
Authors: Mohammed Victoria , Reiss Michael J. , Hargreaves Eleanore 
Published: June 2022

AbstractIn Nigeria, school science education is believed to be impeded by multiple issues, in part resulting from limitations on funding, but there is a dearth of research that attends to the views of learners themselves. The aim of this study was to explore the views of secondary students in Lagos, Nigeria about the school science teaching they received. A multiple case study research design was employed and semi-structured individual (n = 26) and group (n = 4) interviews were undertaken with 14–17-year-old students from four non-fee-paying, mixed-sex public secondary schools. Sampling was purposive, so that the four schools were fairly typical of secondary schools in Lagos, while the interviewed students were preparing to study science at university and follow science career pathways and included both students who were engaged in terms of their participation in class and those who appeared withdrawn. Analysis was undertaken within a theoretical framework derived partly from Vygotsky’s socio-cultural theory of teaching and learning and partly from Watkins’ theories of learning. Students articulated how certain teaching methods, such as learning with and from others in group work, using familiar examples as applications of knowledge and undertaking practical work, were felt to aid their learning of science. These views align with the sorts of approaches to teaching and learning advocated by both Vygotsky and Watkins. It was concluded that there exists quite a gap between what the students said were effective ways of their being taught science and what were often their experiences. Some of the differences are to do with funding shortages but others are to do with pedagogy and terminal assessment.
Redistricting Out Descriptive Representation: The Harmful Effect of Splitting ZIP Codes on the Constituent–Representative Link
Authors: Steelman Tyler S. , Curiel John A. 
Published: June 2022

AbstractRedistricting poses a potential harm to American voters in limiting choice and accountability at the polls. Although voters still retain their right to contact their representatives, research shows that the confusion created when redistricting divides ZIP codes confounds the constituent–representative link. We build on existing research that shows splitting ZIP codes across multiple congressional districts leads to harms in representation. Specifically, we examine the role of splitting ZIP codes on the recognition of the racial group membership of one’s Congressional representative, a foundational component of the descriptive representation of racial minority voters via minority–majority districts in the United States. We find that citizens living in split ZIP codes are significantly less likely to know the race of their member of Congress. This occurs even when controlling for a host of factors including the race and partisanship of the constituent, the tenure of the member, and the amount of time a constituent has lived in their congressional district. Our work provides further evidence of the democratic harms experienced by American citizens living in ZIP codes that are split between multiple congressional districts. This work also points to the representational harms produced by poor district design on the representation of American voters.
The association between screen media quantity, content, and context and language development
Authors: ALROQI Haifa , SERRATRICE Ludovica , CAMERON-FAULKNER Thea 
Published: June 2022

AbstractThis study investigates the influence of the quantity, content, and context of screen media use on the language development of 85 Saudi children aged 1 to 3 years. Surveys and weekly event-based diaries were employed to track children’s screen use patterns. Language development was assessed using JISH Arabic Communicative Development Inventory (JACDI). Findings indicate that the most significant predictor of expressive and receptive vocabulary in 12- to 16-month-olds was screen media context (as measured by the frequency of interactive joint media engagements). In older children (17- to 36-month-olds), more screen time (as measured by the amount of time spent using screens, the prevalence of background TV at home, and the onset age of screen use) had the highest negative impact on expressive vocabulary and mean length of utterance. These findings support health recommendations on the negative effects of excessive screen time and the positive effects of co-viewing media with children.