bluuebunny/crossref_metadata_2025_split huggingface dataset:
Police departments and care continuity for autistic youth in suicidal crisis
Authors: McGhee Hassrick Elizabeth , Weissinger Guy , VanFossen Catherine , Milani Rose , Ventimiglia Jonas , Hoffman Isaiah Delane-Vir , Wintersteen Matthew , Atte Tita , Fernandes Sherira , Diamond Guy 
Published: April 2022

PurposeAutistic youth face higher risks for experiencing mental health crises. To develop and test a county-level social network measure of care coordination between police departments and other systems that support autistic youth experiencing suicidal crisis.Design/methodology/approachTo measure the structure of care coordination for autistic youth experiencing suicidal crisis, the authors created a roster of all police departments and youth servicing organizations in two East Coast counties in the United States. They met or exceeded the whole network recruitment threshold of 70% completion in both counties. From the data, the authors created a directed matrix for each county of all reported connections, which they used to create sociograms and calculate standard network measures, including indegree, outdegree and total degree for each organization in the network. Data management and processing were done using R-programming and ORA.FindingsSocial network findings indicated that about half of all police departments surveyed coordinate care for autistic youth in suicidal crisis. Coordination varied by county, with nonpolice organizations acting as connectors between police and other nonpolice organizations. Two structural configurations were found, including a nonpolice organizational hub structure and a lead police structure. More research is needed to determine how different police integration structures shape care coordination for autistic youth.Research limitations/implicationsLimitations include the small number of counties included in the study. A larger sample of counties is required for generalizable results.Practical implicationsThis article introduces new tools and approaches to assist police in building their capacity to measure and improve their coordination of care with other community systems during crisis situations for youth on the autism spectrum. Network science (e.g. matrix and graph theoretic algebra methods) can be used to measure the configuration of relationships police departments have with complex multi-level healthcare systems.Social implicationsImplications for findings include the consideration of police integration across systems in ways that produce new collaboration possibilities to support autistic youth experiencing suicidal crisis.Originality/valueWhile police departments play a critical role in coordinating care for youth in suicidal crisis, little is known if or how police departments collaborate with other systems to provide assistance for autistic youth during a suicidal crisis. Improving care continuity within and between systems could potentially address clinical and structural challenges and reduce risk for autistic youth experiencing a suicidal crisis.
Tacit coordination as a background practice to accounting practices – reflections on Vollmer’s case for a sociological super-theory of accounting
Authors: Ahrens Thomas 
Published: April 2022

Purpose
The purpose of this paper is primarily methodological. This paper aims to complement the novel sociological argument of Hendrik Vollmer’s paper on tacit coordination of accounting practices with a more familiar theory of accounting practice nexuses that has been stimulating an emerging stream of accounting research. The intention is to suggest some ways in which Vollmer’s ideas can be given traction, especially in field studies of accounting.

Design/methodology/approach
This study uses Theodore Schatzki’s practice theory to explore some of the ways in which elements of tacit coordination might be researched in accounting field studies.

Findings
Tacit coordination can be understood as a background practice that could operate as a dispersed practice in Schatzki’s sense. A practice theory perspective on tacit coordination is suggestive of a number of ways of studying the meaningful cultural contexts as part of which accounting operates. It emphasises, in particular, the active nature of silent, tacit coordination; attending to general knowledge practical know-how, rules and teleoaffectivity as four determinants of practices as specified by Schatzki; and the materiality of coordination.

Research limitations/implications
It has implications for field research insofar as it heightens the researcher’s awareness of tacit coordination as a potentially important set of practices and suggests a number of approaches for studying them. The main suggestions address some of the ways in which tacit coordination can be identified in field research.

Originality/value
This study reflects on the dispersed or integrated nature of tacit coordination practices in accounting.
A novel leaky splice variant in centromere protein J (CENPJ)‐associated Seckel syndrome
Authors: Yadav Navneesh , Kirola Laxmi , Geetha Thenral S , Mittal Kirti , Kadandale Jayarama , Yogev Yuval , Birk Ohad S. , Gupta Neerja , Balakrishnan Prahlad , Jana Manisha , Gupta Meena , Kabra Madhulika , Thelma Bittianda Kuttapa 
Published: April 2022

AbstractPrimary microcephaly and Seckel syndrome are rare genetically and clinically heterogenous brain development disorders. Several exonic/splicing mutations are reported for these disorders to date, but ∼40% of all cases remain unexplained. We aimed to uncover the genetic correlate(s) in a family of multiple siblings with microcephaly. A novel homozygous intronic variant (NC_000013.10:g.25459823T>C) in CENPJ (13q12) segregating with all four affected male siblings was identified by exome sequencing and validated by targeted linkage approach (logarithm of the odds score 1.8 at θ 0.0). RT‐PCR of CENPJ in affected siblings using their EBV derived cell lines showed aberrant transcripts suggestive of exon skipping confirmed by Sanger sequencing. Significantly reduced wild type transcript/protein in the affected siblings having the splice variant indicates a leaky gene expression of pathological relevance. Based on known CENPJ function, assessing for mitotic alterations revealed defect in centrosome duplication causing mono/multicentrosome(s) at prophase, delayed metaphase, and unequal chromosomal segregation in patient cells. Clinical features witnessed in this study expand the spectrum of CENPJ‐associated primary microcephaly and Seckel syndrome. Furthermore, besides the importance of regulatory variants in classical monogenic disorders these findings provide new insights into splice site biology with possible implications for ASO‐based therapies.
Human forkhead box protein 3 gene variants associated with altered susceptibility to idiopathic recurrent pregnancy loss: A retrospective case‐control study
Authors: Bahia Wael , Zitouni Hedia , Kanabekova Perizat , Bauyrzhanova Zhansaya , Shaimardanova Moldir , Finan Ramzi R. , Aimagambetova Gulzhanat , Almawi Wassim Y. 
Published: April 2022

AbstractBackgroundThe pathogenesis of recurrent pregnancy loss (RPL) is multifactorial and not completely elucidated. Dysregulated immunity was implicated with RPL, in which regulatory T cells (Tregs) are key. As Tregs development and function are regulated by forkhead box P3 (FOXP3) transcription factor, and as FOXP3 expression is genetically determined, a role for FOXP3 polymorphisms in RPL pathogenesis was suggested.AimTo investigate the association of rs2294021, rs2232365, rs3761548, and rs141704699 FOXP3 variants with idiopathic RPL in Lebanese women.MethodsThis retrospective case‐control study included 386 RPL cases and 398 age‐matched control women. Logistic odds ratios (OR) were estimated with 95% confidence interval after adjustment; a significance value of P<.05 was set.ResultsSignificantly lower rs22944021 and rs2232365 minor allele frequency (MAF) was found in patients with idiopathic RPL in comparison with the control group. Furthermore, statistically significantly lower frequency of heterozygous and homozygous rs2294021 and rs2232365 genotypes was seen in controls, while significantly lower rs3761548 heterozygous genotype frequencies were found in the patient group. Obesity, antihypertension treatment, smoking, positive RPL family history, abortion state, and infertility treatment correlated negatively with rs2294021, while rs2232365 negatively correlated with obesity, and rs3761548 negatively correlated with infertility treatment. Marked linkage disequilibrium (LD) was noted among FOXP3 SNPs, with TGCC and CGAC haplotypes being positive, while CAAC, CACC, and TGAC haplotypes being negatively associated with RPL risk. Except for CGAC, the association of these haplotypes with RPL persisted after adjustment.ConclusionFOXP3 gene variants and haplotypes are associated with altered incidence of RPL, proposing the role of Treg in RPL pathogenesis.
Standardized 10‐step approach for successfully performing a hysterectomy via vaginal natural orifice transluminal endoscopic surgery
Authors: Housmans Susanne , Stuart Andrea , Bosteels Jan , Deprest Jan , Baekelandt Jan 
Published: April 2022

AbstractVaginal natural orifice transluminal endoscopic surgery (NOTES) is a novel technique for minimally invasive gynecological surgery. Adequate training and standardization are key elements to patient safety and quality of care. Based on consensus statements and expert opinion; we report a step‐by‐step guidance for hysterectomy via natural orifice transluminal endoscopy. A detailed description is presented of pre‐ and postoperative care, and the instruments and equipment used, and surgical steps are illustrated by photographic images. This report can guide surgeons in their training to perform a hysterectomy via NOTES.
Cardiometabolic profile and urinary metabolomic alterations in non‐functioning adrenal incidentalomas: A review
Authors: Araujo‐Castro Marta 
Published: April 2022

AbstractBackgroundThe incidence of adrenal incidentalomas (AIs) has increased over the last 20 years, most of which are apparently non‐functioning adrenal adenomas. However, increased evidence supports the existence of an association between non‐functioning adrenal incidentalomas (NFAI) and an unfavourable cardio‐metabolic profile.MethodsThis study offers a comprehensive review of the available evidence supporting a higher cardiometabolic risk in NFAIs compared to controls without adrenal tumours. Moreover, it summarises the studies focused on the differential urinary metabolomic profile of NFAI and controls without adrenal lesions.ResultsThis adverse metabolic profile of patients with NFAI includes a higher prevalence of insulin resistance, obesity, hypertension, hyperglycaemia, dyslipidaemia, and cardiovascular alterations and mortality compared to healthy controls without adrenal tumours. Although the pathophysiology that explains the association between NFAI and the parameters of metabolic syndrome and cardiovascular risk is a relatively unexplored field of study, some evidence supports that there are a series of incipient alterations in cortisol metabolism not detected with the classical tests that led to this detrimental profile. These alterations may be potentially detected by a comprehensive metabolomics approach. Several studies detected a shift towards an increase of urinary cortisol metabolites excretion in NFAIs compared to controls without adrenal tumours.ConclusionIn view of the higher cardiometabolic risk in NFAI than in controls without adrenal tumours, and the detected alterations in metabolomics profile of NFAI, I propose that the term of NFAI should be changed for another term that best fits to its linked cardiometabolic profile.
Automated measurement of coagulation and fibrinolytic activation markers: Outcomes in coronavirus disease 2019 (COVID‐19) patients
Authors: Gardiner Chris , Mackie Ian J. , MacCallum Peter , Platton Sean 
Published: April 2022

AbstractBackgroundSevere coronavirus disease 2019 (COVID‐19) is characterized by marked hypoxaemia and lung oedema, often accompanied by disordered blood coagulation and fibrinolytic systems, endothelial damage and intravascular fibrin deposition.Patients/MethodsWe present a retrospective observational study of 104 patients admitted to hospital with COVID‐19. Plasma samples were collected within 72 h of admission. In addition to routine coagulation and haematology testing, soluble thrombomodulin (sTM), thrombin‐antithrombin (TAT), tissue plasminogen activator‐plasminogen activator inhibitor 1 complex (tPAI‐C) and plasmin‐α2 antiplasmin complex (PIC) were performed by automated chemiluminescent enzyme immunoassays.ResultsSignificantly higher levels of D‐dimer, TAT, sTM and tPAI‐C were observed in non‐survivors compared to survivors. To confirm which parameters were independent risk factors for mortality, multiple logistic regression was performed on D‐dimer, TAT. sTM, tPAI‐C and PIC data. Only increasing sTM was significantly associated with mortality, with an odds ratio of 1.065 for each 1.0 TU/mL increment (95% CI 1.025–1.115).ConclusionsOf the haemostatic variables measured, sTM, which can be rapidly assayed, is the best independent predictor of mortality in patients hospitalized with COVID‐19, and this suggests that endothelial dysfunction plays an important role in disease progression.
Online social support and collective empowerment: Serial mediation effect on self‐efficacy among mothers of children with type 1 diabetes
Authors: Uhm Ju‐Yeon , Kim Myoung Soo 
Published: April 2022

AbstractAimTo identify a serial multiple mediation effect of social support in online health communities and collective empowerment on the relationship between diabetes‐related burden (DRB) and self‐efficacy, among mothers using a continuous glucose monitoring device for children with type 1 diabetes (T1D).DesignA secondary analysis, cross‐sectional, descriptive study.MethodsData were obtained from 198 mothers of children with T1D via a web survey, from August to September 2020. Measures used were the Collective Empowerment in the Online Health Community Scale, a modified version of the Multidimensional Scale of Perceived Social Support, Problem Areas in Diabetes Survey—Parent Revised version and a modified version of the Maternal Self‐efficacy for Diabetes Management Scale. Data were analysed using SPSS 25.0, and PROCESS MACRO for SPSS v3.5.ResultsA serial multiple mediation model was used. The indirect effects of both social support in online health communities and collective empowerment were identified in the relationship between DRB and diabetes self‐efficacy (DSE). However, there was no indirect effect of social support in online health communities on these relationships.ConclusionThese findings suggest that online social support alone has a limited role in chronic disease management self‐efficacy. Collective empowerment should be a strategic component in intervention development using online health communities to strengthen DSE in mothers of children with T1D.ImpactThis study provides novel insights into the functional mechanism of online health communities for T1D. Peer mentor coaching by parents of children with T1D effectively helps other children's parents with its recent diagnosis. The findings recognize a need for strategies enhancing collective empowerment among parents of children with T1D. Along with peer coaching, these strategies should strengthen knowledge of resources and methods to impact social change as well as resource mobilization for collective actions.
Social–economic impact of infection after cosmetic facial injection: A retrospective study
Authors: Zheng Shaoluan , Feng Zihao , Chen Chenxi , He Anqi , Liu Jiaqi 
Published: April 2022

AbstractBackgroundThe overwhelming interest in economically cost‐effective treatments had led to an increase in the development of cosmetic facial injections. Concomitantly, complications have been also on the increasing trend. This article aimed to investigate the social–economic impact caused by infection after cosmetic facial injection.MethodsA retrospective study was conducted between January 2014 and December 2019. Information including demographics, location of the original injection site, treatments, economic loss, and time away from work associated with complications was documented. Patients were asked to complete 2 FACE‐Q domains 4 weeks after the first presentation, including quality of life and patient experience.ResultsComplete data were available for 12 patients. All patients were female; the mean age was 32.66 years (range, 26–49 years). The mean therapeutic cost of atypical mycobacterium was 18170.58 USD. The mean time away from work was 51.25 days (range, 21–103 days). The mean cost of time away from work was 400.80 USD (range, 164.23–805.50 USD). From FACE‐Q, patients reported a decreased quality of social life, including social function (38.83 ± 12.10), psychological distress (48.67 ± 11.01), and early‐life impact (39.92 ± 10.15). Patients also reported low satisfaction with their decision to undergo the cosmetic facial injection.ConclusionsInfection after cosmetic facial injection comes at a considerable social–economic impact on patients. Patients who responded in this study were extremely unsatisfied with the quality of life following the infection.
Associations among serum insulin, calprotectin, and C‐reactive protein concentrations in Miniature Schnauzers with idiopathic hyperlipidemia before and after feeding an ultra‐low‐fat diet
Authors: Xenoulis Panagiotis G. , Heilmann Romy M. , Stavroulaki Eva M. , Riggers Denise S. , Gneipel Laura J. , Suchodolski Jan S. , Steiner Jörg M. 
Published: April 2022

AbstractBackgroundMiniature Schnauzers (MS) commonly have idiopathic hypertriglyceridemia (HTGL), which is associated with insulin resistance (IR) and a subclinical inflammatory phenotype.ObjectivesDetermine the association between indicators of IR and inflammatory biomarkers in MS with and without HTGL and identify how indicators of IR are affected by dietary intervention in MS with HTGL.AnimalsSeventy MS with HTGL and 79 MS without HTGL. In addition, 15 MS with HTGL were placed on a low‐fat diet.MethodsSerum concentrations of triglycerides, cholesterol, calprotectin, insulin, and glucose were compared between groups.ResultsSerum glucose and calprotectin concentrations (shown to be higher in MS with HTGL than in MS without HTGL) were inversely correlated (ρ = −.28; P < .001). After dietary intervention, median serum insulin concentrations were 8.1 mU/L compared to 20.8 mU/L before dietary intervention (P = .06). Dogs with complete resolution of HTGL after dietary intervention (5 dogs) had significantly lower serum insulin concentrations compared to baseline (P = .03).Conclusion and Clinical ImportanceThe subclinical inflammatory phenotype in MS with HTGL appears to be associated with IR. Resolution of HTGL by dietary intervention is associated with a decrease in serum insulin concentrations. The implication of the increase in serum calprotectin concentrations after resolution of HTGL warrants further study.
Comparing spatial interaction models and flow interpolation techniques for predicting “cold start” bike‐share trip demand
Authors: Liu Zheng , Oshan Taylor 
Published: April 2022

AbstractBike‐sharing systems are expanding rapidly in metropolitan areas all over the world and individual systems are updated frequently over space and time to dynamically meet demand. Usage trends are important for understanding bike demand, but an overlooked issue is that of “cold starts” or the prediction of demand at a new station with no previous usage history. In this article, we explore a methodology for predicting the bike trips from and to a cold start station in the NYC Citi Bike system. Specifically, gravity‐type spatial interaction model and spatial interpolation models, including natural neighbor interpolation and kriging, are employed. The overall results come from experiments of a real‐world bike‐sharing system in NYC and indicate that the regression kriging model outperforms the other models by taking advantage of the robustness and interpretability of gravity‐type spatial interaction regression models and the capability of ordinary kriging to capture spatial dependence.
Accuracy of artificial intelligence software for the detection of confirmed pleural effusion in thoracic radiographs in dogs
Authors: Müller Thiago Rinaldi , Solano Mauricio , Tsunemi Mirian Harumi 
Published: April 2022

AbstractThe use of artificial intelligence (AI) algorithms in diagnostic radiology is a developing area in veterinary medicine and may provide substantial benefit in many clinical settings. These range from timely image interpretation in the emergency setting when no boarded radiologist is available to allowing boarded radiologists to focus on more challenging cases that require complex medical decision making. Testing the performance of artificial intelligence (AI) software in veterinary medicine is at its early stages, and only a scant number of reports of validation of AI software have been published. The purpose of this study was to investigate the performance of an AI algorithm (Vetology AI®) in the detection of pleural effusion in thoracic radiographs of dogs. In this retrospective, diagnostic case–controlled study, 62 canine patients were recruited. A control group of 21 dogs with normal thoracic radiographs and a sample group of 41 dogs with confirmed pleural effusion were selected from the electronic medical records at the Cummings School of Veterinary Medicine. The images were cropped to include only the area of interest (i.e., thorax). The software then classified images into those with pleural effusion and those without. The AI algorithm was able to determine the presence of pleural effusion with 88.7% accuracy (P < 0.05). The sensitivity and specificity were 90.2% and 81.8%, respectively (positive predictive value, 92.5%; negative predictive value, 81.8%). The application of this technology in the diagnostic interpretation of thoracic radiographs in veterinary medicine appears to be of value and warrants further investigation and testing.
Supplemental Material: An explosive volcanic origin identified for dark sand in Aeolis Dorsa, Mars
Authors: Burr Devon M. , al. et 
Published: April 2022

<p>(1) Methods, Figures S1–S3, and captions for additional supplemental information, (2) Animation S1, (3) the ArcGIS geodatabase from this work, (4) CRISM browse products, and (5) the ArcGIS database with the locations of grain size derivations. </p>