bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengembangan Media Pembelajaran E-komik IPA Pada Materi Sistem Pencernaan Manusia Untuk Siswa kelas VIII SMP
Authors: Kasih Putri Pancar , Muhaimin Muhaimin , Hariyadi Bambang 
Published: April 2022

Media is one of the important components that must exist in a learning process. The aim of this research is to develop science e-comic for human digestive system material for VIII-grade junior high school students. This study uses the ADDIE development model (Analysis, Design, Development, Implementation, and Evaluation). The data collection instrument used in the form of a validation questionnaire of design experts, material experts, teacher perceptions, and student perceptions of science e-comics. This research was conducted at SMP Insan Madani Boarding School Jambi. The results of validation by material experts obtained a percentage of 90.67% (very valid) and the assessment of media experts obtained a percentage of 90% (very valid). Assessment by the teacher obtained a percentage of 93.125% (very good). The results of the one-on-one trial obtained a total score of 96.67% (very good), the small-group trial scored 94.33% (very good), and the large group trial obtained a score of 92% (very good). In conclusion, science e-comic learning media is suitable for use in distance learning (online).
Key words: Learning Media, E-Comic, Human Digestive System

Abstrak. Media merupakan salah satu komponen penting yang harus ada di dalam suatu pembelajaran. Tujan penelitian ini adalah mengembangkan e-komik IPA materi sistem pencernaan manusia untuk siswa kelas VIII SMP. Penelitian ini menggunakan model pengembangan ADDIE (Analysis, Design, Development, Implementation, and Evaluation). Instrumen pengumpulan data yang digunakan berupa angket validasi ahli desain, ahli materi, persepsi guru dan persepsi siswa terhadap e-komik IPA. Penelitian ini dilakukan di SMP Insan Madani Boarding School Jambi. Hasil validasi oleh ahli materi memperoleh persentase 90,67% (sangat valid) dan penilaian ahli media memperoleh persentase 90% (sangat valid). Penilaian oleh guru memperoleh persentase 93,125% (sangat baik). Hasil uji coba satu-satu diperoleh skor total 96,67% (sangat baik), uji coba kelompok kecil memperoleh nilai 94,33% (sangat baik), dan uji coba kelompok besar memperoleh nilai 92% (sangat baik). Kesimpulannya media pembelajaran e-komik IPA layak digunakan dalam pembelajaran jarak jauh (daring).
Kata kunci: Media Pembelajaran, E-komik, Sistem Pencernaan Manusia
"What Do These Stones Mean?": Biblical Theology and a Motif in Joshua
Authors: HUBBARD, ROBERT L. 
Published: April 2022

Abstract
The book of Joshua seems to contradict itself, praising Israel's complete conquest of Canaan while reporting the survival of Rahab and the Gibeonites. This paper responds to the problem by studying a recurrent motif in Joshua 3–10: a stone structure that memorializes past events "to this day" (used four times). The stones motif contributes to the literary coherence of the context around the theme of Yahweh's conquest of his enemies. More important, the stone structure at Gilgal (chaps. 3–4) hints that Canaanites besides Rahab might receive divine favor, while Achan's burial heap (chap. 7) suggests that Yahweh values obedience over ethnicity and welcomes religiously responsive foreigners. Similarly, the Gibeonite episode (chaps. 9–10) demonstrates divine acceptance of Israel's arrangement with Gibeon as an exception to the ḥerem mandate. Thus, Joshua 3–10 not only reports the survival of foreigners but also quietly advocates divinely-sanctioned exceptions to the mandate in certain cases. In this way, the perceived tension between the mandate and the survival of foreigners lessens. This article also explores the theological themes that the motif sounds and the model of biblical theology that underlies it.
1 Thessalonians 4:4: Breaking the Impasse
Authors: SMITH JAY E. 
Published: April 2022

Abstract
The crux interpretum τὸ ἑαυτοῦ σκεῦος κτᾶσθαι ἐν ἁγιασμῷ καὶ τιμῇ in 1 Thess 4:4 has traditionally been understood in one of three ways: (1) "acquire a wife for himself in holiness and honor" (NAB); (2) "live with your wife in a holy and honorable way" (TEV); and (3) "control your own body in holiness and honor" (NRSV). These three views are thoroughly evaluated, and new evidence, especially concerning the referent of σκεῦος as well as the semantic force of the present infinitive κτᾶσθαι, is brought to bear on the problem. This analysis suggests that by τὸ ἑαυτοῦ σκεῦος κτᾶσθαι ἐν ἁγιασμῷ καὶ τιμῇ Paul means that each one is to control his or her own body in holiness and honor or, perhaps more specifically, that each one is to control his or her sexual organ in holiness and honor.
Where Should Twenty-First-Century Evangelical Biblical Scholarship Be Heading?
Authors: BLOMBERG CRAIG L. 
Published: April 2022

Abstract
Recent developments and resulting needs are assessed in a variety of areas: historical Jesus research and issues of OT historicity, Pauline theology and theologies of individual OT books, critical methods for the study of both Testaments and especially historical study, contextualized biblical studies, biblical ethics, the application of the OT in the NT age and the quotation of the Old in the New, Greek and Hebrew grammar, OT textual criticism, and the interaction between church and the academy.
Jesus and the Twelve
Authors: MCKNIGHT SCOT 
Published: April 2022

Abstract
IBR Jesus Project Paper 2. That Jesus associated himself especially with twelve of his followers is a datum firmly established by good arguments across a broad spectrum of modern Jesus studies. But why Jesus chose the Twelve is in need of serious reconsideration because the standard, eschatological explanation has rarely been examined. A careful examination of the evidence pertaining to the number "twelve" in the Hebrew Bible and in ancient Jewish sources suggests that Jesus chose the Twelve to evoke the twin themes of covenant renewal (a Joshua theme) and eschatological restoration (with the reunification of the twelve tribes implied).
πάροικος καὶ παρεπίδημος: Proselyte Characterizations in 1 Peter?
Authors: SELAND TORREY 
Published: April 2022

AbstractIn some diaspora Jewish works, the terms πάροικος and παρεπίδμος belong to the semantic field of "proselyte/proselytism." In 1 Peter, however, they do not indicate that the recipients of the letter are considered former proselytes. The terms function rather as metaphors drawn from the social world of proselytes (source domain), characterizing the social situation of the Petrine Christians (target domain), especially throwing light on the social estrangement of the Christian converts in the Greco-Roman societies of Asia Minor as understood by the author.
Equilibrium and the Sacred Compass: The Structure of Leviticus
Authors: Walton John H. 
Published: April 2022

Abstract
Despite the highly organized features of Leviticus, interpreters have found it difficult to identify a cohesive structure to the book. One possible explanation may be that we have been deterred by presuppositions. We have generally seen the sacrificial system in terms of providing a means to care for the sin and impurity of the people. An alternative approach, however, focuses on the need to preserve and maintain sacred space. This paper builds on this concept and explores the ways that such an adjustment in our thinking suggests a new understanding of the structure and focus of Leviticus.
The Social Matrix of Women's Speech at Corinth: The Context and Meaning of the Command to Silence in 1 Corinthians 14:33b–36
Authors: PAIGE TERENCE 
Published: April 2022

Abstract
A reexamination of Greek and Roman culture highlights women's positive role in religion, as Paul also grants, as well as the nuanced but guarded interactions between the sexes. Paul's injunction to women in 1 Cor 14:34–35 was meant to prevent casual interaction between married women and non-family men in the context of worship, not to prevent sacral speech. This behavior was seen as sexually aggressive, bringing shame on these women and the church in society's eyes.
Paul in Arabia
Authors: HENGEL MARTIN 
Published: April 2022

Abstract
The few hints of Paul's time in Arabia (or Nabatea) are much more important than is suggested by the scant attention they typically receive in NT scholarship. Careful consideration of all factors leads to the conclusion that Paul's stay in Arabia was somewhat longer than is usually thought and resulted in successful missionary activity. However, this activity also provoked vigorous opposition on the part of synagogue authorities, as well as state authorities.
A Rejoinder to Joel F. Williams's "Is Mark's Gospel an Apology for the Cross?"
Authors: GUNDRY ROBERT H. 
Published: April 2022

Abstract
Against Joel Williams's critique, this rejoinder argues for a Markan Christology of divine strength in word and deed to counteract the shame of Jesus' crucifixion, thus to convert unbelievers, not a Christology of weakly human suffering designed to brace believers for the endurance of persecution. In his Gospel, Mark included material seemingly antithetical to such an apologetic, evangelistic aim because he felt obliged to write up everything he had heard Peter say about Jesus' ministry (so John the Elder). At the same time Mark tweaked this very material in ways that allied it to the massive amount of power-material (much underplayed by Williams) in service of the apologetic, evangelistic aim. Even Mark's passion narrative exhibits such tweaking, for example, in emphases on the fulfillments of Jesus' various predictions, on Jesus' dying with a burst of strength, and on the shortness of time he hung on a cross. This interpretation of Mark's text arose out of a close reading, not out of a presupposition.
β-Cell Succinate Dehydrogenase Deficiency Triggers Metabolic Dysfunction and Insulinopenic Diabetes
Authors: Lee Sooyeon , Xu Haixia , Vleck Aidan Van , Mawla Alex M. , Li Albert Mao , Ye Jiangbin , Huising Mark O. , Annes Justin P. 
Published: April 2022

<p>Mitochondrial dysfunction plays a central role in Type 2 Diabetes (T2D); however, the pathogenic mechanisms in pancreatic β-cells are incompletely elucidated. Succinate dehydrogenase (SDH) is a key mitochondrial enzyme with dual functions in the TCA cycle and electron transport chain (ETC). Using human diabetic samples and a mouse model of β-cell-specific SDH ablation (SDHBβKO), we define SDH deficiency as a driver of mitochondrial dysfunction in β-cell failure and insulinopenic diabetes. β-Cell SDH deficiency impairs glucose-induced respiratory oxidative phosphorylation and mitochondrial membrane potential (ΔΨm) collapse, thereby compromising glucose-stimulated ATP production, insulin secretion and β-cell growth. Mechanistically, metabolomic and transcriptomic studies reveal that the loss of SDH causes excess succinate accumulation, which inappropriately activates mTORC1-regulated metabolic anabolism, including increased SREBP-regulated lipid synthesis. These alterations, which mirror diabetes-associated human β-cell dysfunction, are partially reversed by acute mTOR inhibition with rapamycin. We propose SDH deficiency as a contributing mechanism to the progressive β-cell failure of diabetes and identify mTORC1 inhibition as a potential mitigation strategy. </p>
Mitofusins Mfn1 and Mfn2 are Required to Preserve Glucose- But Not Incretin-Stimulated Beta Cell Connectivity and Insulin Secretion
Authors: Georgiadou Eleni , Muralidharan Charanya , Martinez Michelle , Chabosseau Pauline , Akalestou Elina , Tomas Alejandra , Wern Fiona Yong Su , Stylianides Theodoros , Wretlind Asger , Legido-Quigley Cristina , Jones Ben , Noriega Livia Lopez , Xu Yanwen , Gu Guoqiang , Alsabeeh Nour , Cruciani-Guglielmacci Céline , Magnan Christophe , Ibberson Mark , Leclerc Isabelle , Ali Yusuf , Soleimanpour Scott A. , Linnemann Amelia K. , Rodriguez Tristan A. , Rutter Guy A. 
Published: April 2022

<p>Mitochondrial glucose metabolism is essential for stimulated insulin release from pancreatic beta cells. Whether mitofusin gene expression, and hence mitochondrial network integrity, is important for glucose or incretin signalling has not previously been explored. Here, we generated mice with beta cell-selective, adult-restricted deletion of the mitofusin genes <em>Mfn1</em> and <em>Mfn2 </em>(β<em>Mfn1/2 </em>dKO). β<em>Mfn1/2 </em>dKO mice displayed elevated fed and fasted glycaemia and a >five-fold decrease in plasma insulin. Mitochondrial length, glucose-induced polarisation, ATP synthesis, cytosolic and mitochondrial Ca2+ increases were all reduced in dKO islets. In contrast, oral glucose tolerance was more modestly affected in β<em>Mfn1/2 </em>dKO mice and GLP-1 or GIP receptor agonists largely corrected defective GSIS through enhanced EPAC-dependent signalling. Correspondingly, cAMP increases in the cytosol, as measured with an Epac-camps based sensor, were exaggerated in dKO mice. Mitochondrial fusion and fission cycles are thus essential in the beta cell to maintain normal glucose, but not incretin, sensing. These findings broaden our understanding of the roles of mitofusins in beta cells, the potential contributions of altered mitochondrial dynamics to diabetes development and the impact of incretins on this process. </p>
HIF-2α Preserves Mitochondrial Activity And Glucose Sensing in Compensating Beta Cells in Obesity
Authors: Moon Jae-Su , Riopel Matthew , Seo Jong Bae , Herrero-Aguayo Vicente , Isaac Roi , Lee Yun Sok 
Published: April 2022

<p>In obesity, increased mitochondrial metabolism with the accumulation of oxidative stress leads to mitochondrial damage and beta cell dysfunction. In particular, beta cells express anti-oxidant enzymes at relatively low levels and are highly vulnerable to oxidative stress. Early in the development of obesity, beta cells exhibit increased GSIS, in order to compensate for insulin resistance. This increase in beta cell function under the condition of enhanced metabolic stress suggests that beta cells possess a defense mechanism(s) against increased oxidative damage, which may become insufficient or decline at the onset of type 2 diabetes. Here, we show that metabolic stress induces beta cell HIF-2a, which stimulates anti-oxidant gene expression (e.g. <em>Sod2</em> and <em>Cat</em>) and protects against mitochondrial ROS and subsequent mitochondrial damage. Knockdown of HIF-2a in Min6 cells exaggerated chronic high glucose-induced mitochondrial damage and beta cell dysfunction by increasing mitochondrial ROS levels. Moreover, inducible beta cell HIF-2a KO mice developed more severe beta cell dysfunction and glucose intolerance on high fat diet, along with increased ROS levels and decreased islet mitochondrial mass. Our results provide a previously unknown mechanism for how beta cell defends against increased metabolic stress to promote beta cell compensation in obesity. </p>
Plato Plays Polis
Authors: Bakewell Geoff 
Published: April 2022

Abstract
At Republic 422e1-423a2, while discussing Callipolis and its ability to wage war, Socrates makes a punning reference to the ancient boardgame polis. In this contest, two opponents deployed sets of identical pessoi (counters) to surround and capture the enemy’s forces. Socrates’ allusion is not simply amusing; it is well-suited to the dialogue’s philosophical content and historical context. With regard to philosophy, Callipolis’ guardians resemble the pessoi. Their training makes them equal and interchangeable, while their personal interests are subordinated to those of the group to discourage dissent (stasis) and promote unity. Elsewhere in the Platonic corpus, learning to play polis is mentioned as part of a philosophical education. In the hands of a skilled practitioner like Socrates, dialectic is like playing polis. With regard to history, the Republic’s main interlocutors (Socrates, Adeimantus, Glaucon) were soldiers known for their bravery. Moreover, its readers remembered the rule of the Thirty Tyrants and its aftermath. Indeed, the dialogue’s arguments about the just city and regime change are framed by an allusion to the movements of Thrasybulus and Critias and their respective troops around the game board of Attica. At Athens, polis was played for high stakes, namely the polis itself.
Board Games in Ancient Fiction: Egypt, Iran, Greece
Authors: Konstantakos Ioannis M. 
Published: April 2022

AbstractBoard games are often used as a plot motif in modern genre fiction, especially in detective and adventure stories. In these types of narrative, a well-known pattern of storytelling or literary structure (e.g., the treasure hunt, the detection of serial crimes, the iniatory course, or the medieval tale collection) is reworked and adapted to the rules and phases of a board game such as chess,jeu de l’oie, or the tarot card pack. This literary practice is very ancient and may be traced back to a number of novelistic compositions of the ancient Near East, dating from the 1st millennium BC to late antiquity. In the Demotic EgyptianTale of Setne Khaemwaset, from the Saite period, the protagonist Setne plays a board game (probablysenet) with the mummy of a long dead and buried magician, in order to gain a powerful book of spells. The widespread Near-Eastern story-pattern of the magical competition is here superimposed on the procedure of a celebrated Egyptian game. In a late Hellenistic Greek novella inspired by theOdyssey(Apion of Alexandria,FGrH616 F36) Penelope’s suitors play an elaborate game of marbles (petteia) in order to determine which one of them will marry the queen. This is a playful rewriting of the famous bow contest of the Homeric epic. A Sasanian novelistic work, theWizārišn ī čatrang, adapts the age-old legend of the riddle contest of kings; the riddles are replaced with board games (chess and backgammon), which the opponents invent and propose to each other as difficult puzzles for solution. In all these texts the board game becomes a central symbol of the transformative and innovative power of literary narrative.
“How is he entitled to say this?”: Constructing the identities of experts, ordinary people, and presenters in Swedish television series on climate change
Authors: Filimonov Kirill , Carpentier Nico 
Published: April 2022

Abstract
In this article, we analyse mediated representations of elite and non-elite voices about climate change, by juxtaposing two Swedish non-fiction television series: one narrates the work of environmental scientists, the other discusses climate change with diverse citizens in a vox pop format. We argue that the discursive practices of these programmes reproduce the antagonistic subject positions of experts and ordinary people, allocating them radically different positions of power in relation to climate change. Whereas the experts are presented as actors of change with the knowledge to solve the crisis, ordinary people are shown as passive recipients of advice and moral judgment, in need of change. In addition, we highlight the role of media professionals in these articulations. The article shows how these subject positions support persuasionist strategies, but also how the elite/non-elite juxtaposition tends to exclude the latter from a meaningful engagement on equal terms.
Aesthetics of Affliction
Authors: Guevara Alberto , Nouvet Elysée 
Published: April 2022

In making Aesthetics of Affliction our theme for this first issue, our goal was to engage immediately with questions that must remain central in a journal dealing with corpo-realities of structural violence, the senses, and the theatricality of power. These questions are: how can we talk to experiences and situations that evade translation and that are mired with legacies of objectification? What are the possibilities, limits, hopes, and risks when addressing non-linear moves of power, the work of violence, and social yet also intensely subjective effects/affects?
Embolia gasosa como complicação associada ao cateter venoso central: revisão integrativa
Authors: Queiroz Ann Karla Corrêa , Filho Wilson de Oliveira , Matos Adriano Medina , Santos Lenon Barros , Magalhães Rafaelly Taketomi de 
Published: April 2022

Objetivo: Constatar as evidências científicas sobre a embolia gasosa como complicação ligada ao cateter venoso central. Métodos: Trata-se de uma revisão bibliográfica integrativa, com a seleção dos artigos realizada nas plataformas Lilacs, Scielo, Biblioteca Virtual de Saúde e Pubmed, publicados. A análise dos dados foi através de pré-análise, exploração do material, tratamento dos dados e interpretação dos dados, com resultados sendo expostos em quadro. Resultados: Foram encontrados nove artigos correspondente ao nosso objetivo. Segundo a literatura o Cateter Venoso Central (CVC) apresenta alta frequência de instalação em pacientes na prática hospitalar, representando por conseguinte alto potencial de complicações como a embolia gasosa, que é pouco reconhecida, mas que ocorre tanto na inserção do CVC como na sua retirada. Alguns fatores de risco podem contribuir para o desenvolvimento de uma embolia gasosa, como o mau posicionamento do paciente, hipovolemia, inalação espontânea durante o procedimento e não aplicação de selos de cateter. A sintomatologia vai desde uma dispneia súbita até a morte caso não haja conduta terapêutica adequada. Considerações finais: Cateteres venosos centrais são amplamente utilizados na prática clínica hospitalar e apesar de não ser a complicação mais evidente, a embolia gasosa é rara e potencialmente fatal advinda do cateterismo venoso central.
Perspectivas de gestantes acerca do parto normal em uma Unidade Básica de Saúde ao Sul do Tocantins
Authors: Silva Loren Kelly Vieira da , Mota Annyelle Figueiredo , Alcântara Denise Soares de , Rodrigues Grace Kelly Lourenço , Veras Hedrielly Henrique Fontoura , Rodrigues Kelly Loraynne Lourenço , Oliveira Kleverson Wessel de , Ribeiro Mirelly da Silva , Azevedo Nara  Fernanda Resende , Miquelin Wictor da Silva 
Published: April 2022

Objetivo: Analisar a perspectiva das gestantes acerca do parto normal. Métodos: Realizou-se um estudo descritivo de abordagem qualitativa, executado com gestantes em uma Unidade Básica de Saúde ao Sul do Tocantins. Resultados: A amostra foi composta por 14 gestantes, com idade gestacional entre 14 semanas e 40 semanas e 5 dias, com faixa etária de 20 a 38 anos de idade, sendo que 38,46% das gestantes estavam até o momento apresentando 7 ou + consultas de pré-natal. 69,23% afirmaram não acreditarem ter malefício nesse tipo de parto. 15,38% relatam que as complicações no pré, trans e pós-parto e todo o sofrimento e dor é uma grande desvantagem. Conclusão: Os benefícios do parto normal foram conhecidos por grande parte das gestantes, mesmo que a grande maioria nunca o tinha vivenciado. Verificou-se que as atividades educativas exerciam influências positivas sobre a visão da gestante em relação ao parto normal. Porém, a maioria das gestantes acabavam buscando informações a respeito dessa temática em meios eletrônicos, pois os profissionais de saúde apresentavam pouco enfoque em realizar educação em saúde a respeito dos tipos de parto, seus benefícios, malefícios e especificidades, sobretudo o profissional enfermeiro.