bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative assessment of modern parameters of glycemic control in children with type 1 diabetes after switching to fast-acting insulin aspart using Flash Glucose Monitoring in real clinical practice
Authors: Girsh Y. V. , Kiyaev A. V. , Slovak M. A. , Korneva I. V. , Promin I. A. , Yusupova N. A. , Savelyev L. I. 
Published: December 2022

BACKGROUND: Postprandial hyperglycaemia contributes significantly to the lack of glycaemic control in patients with type 1 diabetes mellitus (DM1). At least a quarter of patients forget to inject insulin before meals once a week, and more than 40% of them inject bolus insulin immediately before meals, which does not correspond to the pharmacokinetic effects of ultrashort insulins and determines the need to use insulins with better imitations of physiological insulin secretion.AIM: To assess the effect of fast acting insulin aspart (FIAsp) on the current parameters of glycaemic control in children with DM1 after switching from insulin Asp (iAsp) using continuous glucose monitoring.MATERIALS AND METHODS: A multicenter observational 12-week prospective open-label uncontrolled comparative study was initiated. A group of insufficiently controlled patients were identified (n = 48) including a group on multiple insulin injections therapy (MII) (insulin degludec and IAsp) and a group on continuous subcutaneous insulin infusion (CSII) of iAsp. Three 14-day flash glucose monitoring (FMG) were performed: before transferring patients to FiAsp and after 2 and 12 weeks of the transfer. Key endpoints: HbA1c after 2 and 12 weeks on FiAsp relative to baseline, analysis of 5 FMG target glucose ranges, presented as an ambulatory glycemic profile. Additional indicators: dynamics of insulin daily dose, frequency of glucose self- monitoring, the number of severe hypoglycemia, adverse events that occurred during treatment.RESULTS: 2 weeks after the transfer from IAsp to FIAsp, TIR increased in the entire group of patients: from 53% [44.3; 66.5] to 57% [47.4; 71.0] (p-value = 0.010) and TAR decreased from 38% [24.8; 50.2] to 30.5% [22.0; 45, 0] (p-value = 0.0124). Maintaining and increase time spent in the target glucose ranges during a 12-week observation period, in parallel with a significant decrease in hypoglycemic episodes <3.9 mmol / L per week, on FIAsp therapy naturally leads to an improvement in diabetes control: a decrease in HbA1c from 8.15% up to 7.75% (p-value = 0.0224), more pronounced in the group of patients on CSII — from 7.9% to 7.5% (p-value = 0.028).CONCLUSION: Switching from IAsp to BDIAsp in routine clinical practice in the MII and CSII regimen in children and adolescents with type 1 diabetes allows achieving better glycemic control compared to the previous generation prandial insulin analog Iasp. The better diabetes control is associated with an increase or a trend towards an increase in TIR and a decrease or a trend towards a decrease in TAR and TBR, as well as a significant decrease in episodes of hypoglycemia.
DESIGUALDADES TERRITORIAIS NOS INDICADORES DE MORTALIDADE INFANTIL DO ESTADO DO RIO GRANDE DO SUL, BRASIL
Authors: Faria Rivaldo Mauro 
Published: December 2022

O objetivo deste estudo é analisar as variações espaciais e as desigualdades territoriais nos indicadores de mortalidade infantil do estado do Rio Grande do Sul, Brasil. A pesquisa foi feita ao nível dos municípios, com dados agregados dos anos de 2009 Ã 2013 e tendo em vista os resultados (óbitos) e os determinantes (contexto) da mortalidade infantil. Todos os dados foram coletados em fontes secundárias oficiais, modelados em Sistema de Informação Geográfica e analisados com recursos da estatística espacial. Os resultados mostraram elevados coeficientes de mortalidade infantil (CMI), neonatal (CMIN) e pós-neonatal (CMIPN) nos municípios localizados ao sul do estado e baixos coeficientes ao norte, com tendência à formação de clusters. Em ambos os casos, foram encontradas relações importantes com os indicadores de privação social, cobertura da atenção básica e uso do pré-natal. Conclui-se, pois, que são necessárias políticas de desenvolvimento territorial que associem a redução da pobreza ao aumento da cobertura assistencial, ampliando-se o acesso aos serviços básicos de promoção à saúde infantil.
O USO DE GEOTECNOLOGIAS PARA O MAPEAMENTO DA MALÁRIA NO MUNICÍPIO DE VITÓRIA - ES
Authors: Almeida Rafael Dias de , Santos Alexandre Rosa dos , Louzada Franciane L. Rubini de Oliveira , Santos Gleissy Mary A. D. A. dos 
Published: December 2022

A produção de informações Ã gestão de serviços e formulação de política de saúde é hoje no Brasil um desafio às administrações públicas, na busca por planejamento e atuação mais direta dos serviços de saúde. Assim, a presente pesquisa utiliza em conjunto dados sobre a notificação da doença de veiculação hídrica, a malária, contidos no Sistema de Informação sobre Agravos Notificados (SINAN) e as tecnologias dos Sistemas de Informações Geográficas (SIG), a fim de evidenciar a empregabilidade do SIG como gerador de informações em saúde. A partir dos dados referentes à malária, que ocorreu no período de 1999 a 2005 no Município de Vitória, foram gerados mapas com números de casos para os períodos seco e chuvoso. Diante dos mapas gerados, foi possível conhecer a distribuição espacial da malária, analisar, discutir apontar as possíveis causas para as situações apresentadas. Verifica-se que a utilização conjunta entre o SIG e o SINAN, é uma importante ferramenta da epidemiologia e saúde pública na otimização das informações.
ANÁLISIS ESPACIAL EN SALUD MENTAL: EL CASO DEL HOSPITAL VILARDEBÓ DE MONTEVIDEO-URUGUAY
Authors: Giraldez Carlos Gonzalo 
Published: December 2022

Introducción. Los problemas de salud mental entre la población general han cobrado una importancia creciente, reconociéndose como una preocupación de salud pública: el alcoholismo crónico, la esquizofrenia, la demencia senil, el retraso mental severo y la enfermedad depresiva (COOPER,C.L.,1985).
Objetivos. Analizar espacialmente a la población de género masculino internada en el Centro Hospitalario Psiquiátrico Vilardebó de Montevideo, cuyo origen sea de dicha ciudad. Metodología. Abordaje cuantitativo a partir de un estudio transversal. La información colectada y creada se incorporó a un Sistema de Información Geográfico en Salud y se trató estadísticamente: análisis de clúster y anova. Resultados. Existe un patrón de distribución espacial de dicha población con tendencia a la concentración en ciertas áreas de la ciudad por sobre otras. La patología esquizofrenia presenta no solo la mayor frecuencia en el universo tratado (41,23%) sino una concentración territorial muy intensa hacia el SE de dicha ciudad. Se visualizan áreas de inferencia de aspectos etarios y judiciales de dicha población de alta significación por su incidencia en lo asistencial. Conclusiones. La realización de cartografía en Salud Mental no solo permite observar su expresión territorial sino sus relaciones con el medio físico, hábitat, y factores demográficos. Esto permite orientar planes y políticas sanitarias en pos de una intervención adecuada.
EFEITOS DAS PARTÍCULAS TOTAIS EM SUSPENSÃO (PTS) NA SAÚDE DA POPULAÇÃO DOS BAIRROS DE BENFICA, BONSUCESSO, RAMOS E MANGUINHOS - RIO DE JANEIRO/RJ
Authors: Costa Maria Albertina , Miyashiro Gladys Miyashiro , Campelo Victor , Barbosa Ieda da Costa , Souza Filho Erito Marques de , Silva Isabel , Kligerman Debora Cynamon , Cohen Simone Cynamon 
Published: December 2022

Este trabalho foi desenvolvido nos bairros de Benfica, Manguinhos, Bonsucesso e Ramos, subúrbios industriais do município do Rio de Janeiro, no período de 2000 a 2004, onde o IDH é de aproximadamente 0,8, com uma população de baixa renda, exposta à poluição veicular (próxima Ã Av. Brasil, uma das vias mais movimentadas do Rio de Janeiro) e industrial (refinarias, entre outras). O objetivo deste estudo é apresentar a relação de PTS ou MP, temperatura, umidade relativa do ar e óbitos por doenças cardiovasculares e respiratórias. Para tanto, foram desenvolvidos modelos estatísticos de séries temporais, além de uso do coeficiente de correlação de Pearson, da tendência e freqÃ¼ência como instrumentos para a análise dos dados. Observou-se uma alta mortalidade por doença cardiovascular seguido da respiratória, bem como, exposição crônica de MP ou PTS, além de um pequeno processo de mudança no micro-clima da área. Apesar de não ter sido observado associação estatística de medidas de MP ou PTS, temperatura e umidade relativa do ar com óbitos por doenças cardiovasculares e respiratórias, acredita-se que as concentrações de MP ou PTS e a pequena mudança no micro-clima observado, possam ser fatores que contribuíram para isso, devido à alta ocorrência de óbitos nas faixas do Sensível (101-150ï?­/m3) e Inadequado (151-200ï?­/m3)segundo a tabela IQA-EPA.
PERFIL HISTÓRICO DO ESCORPIONISMO EM AMERICANA, SÃO PAULO, BRASIL
Authors: Brasil Jardel , Zumkeller Stefan , Brites-Neto José 
Published: December 2022

O meio urbano é caracterizado por constantes ações antrópicas que influenciam diretamente na redução de ambiências naturais e modificação de hábitats. Alterações no meio ambiente provocadas pelo homem como, desmatamentos, utilização indiscriminada de agrotóxicos e crescimento urbano desordenado, parecem ser as principais causas de desequilíbrios em populações de escorpiões. No município de Americana, algumas espécies adaptaram-se ao contexto urbano, culminando em aumento de sua frequência sinantrópica. O Tityus serrulatus adaptou-se ao meio domiciliar através do favorecimento das condições ambientais associadas a aspectos de sua fisiologia reprodutiva e de seu hábitat alternativo em galerias de esgoto que se tornaram vias de acesso às residências. Ainda no início do século XX, já havia queixas de casos com escorpiões, favorecidos pela umidade relativa local mais elevada, em razão das áreas hidrográficas que contornavam o município e também pelas áreas rurais de culturas agrícolas (cereais, laranja, banana, melancia, algodão e cana-de-açúcar) existentes Ã época. Este trabalho apresenta contextos históricos das possíveis causas que vieram a contribuir para a origem do escorpionismo em áreas urbanas do município de Americana/SP.
The financing of innovation: an evolutionary approach to firm behavior
Authors: Gomes Leonel Solange , Ferreira Marques Sylvia 
Published: December 2022

This article discusses the financing of innovation based on the evolutionary theory. The goal is to bring together elements that elucidate a firm's behavior towards the innovation process. These elements include technological regimes and the relationship between finance and innovation. The discussion goes further into the evolutionary theory by incorporating the stages of growth of an innovative firm and the preference of innovation funding sources. The conclusion is that for each technological pattern and at each stage of development, a firm tends to present a different type of behavior in seeking financing for innovation.
การประเมินความต้องการจำเป็นในการพัฒนาความรู้และทักษะทางด้านอิเล็กทรอนิกส์อัจฉริยะของแรงงานรองรับยุทธศาสตร์การพัฒนาพื้นที่ภาคใต้
Authors:   Electrical Department, Faculty of industrial Education and Technology, RUTS., Songkhla, Tanaphatsiri Chaiya , Tongpet Bussarakam ,   Faculty of industrial Education and Technology, RUTS., Songkhla, Prasongchan Piya ,   Faculty of industrial Education and Technology, RUTS., Songkhla, Boonsong Wasana ,   Faculty of industrial Education and Technology, RUTS., Songkhla
Published: December 2022

This research aimed to study the current and desirable conditions, assess needs and prioritize the need to develop knowledge and skills necessary for workers' intelligent electronics to support the development strategy in the southern region. The research point was to conduct according to the needs assessment. The research tool was a questionnaire for collecting opinions from a sample group, namely administrators of educational institutions under the Office of Vocational Education Commission and heads of provincial government agencies in the southern provinces and the southern border provinces, totaling 291 people specific sample selection method. The statistics for data analysis include mean, standard deviation, and the priority needs index (PNI) value of the updated PNI_modified .	The results of the research found that:	1) Overall desirable conditions concerning the need for knowledge and skills development in the field of intelligent electronics of workers to support the development strategy in the southern region. There was a high level of demand (x ̅=4.32, S.D.=0.84), which was much higher than the overall current condition where the practice was at a high level (x ̅=3.40, S.D.=1.07).	2) Knowledge and emerging skills: knowledge and emerging skills: knowledge and skills in electronic technology for an intelligent environment are necessary (PNI_modified) was 0.36, with the desired condition being at a high level (x ̅=4.24, S.D.=0.84) and the need for soft skills needs in the future, quantity and statistics have a need (PNI_modified) was 0.29, with a high level of desirable, desirable condition (x ̅=4.36, S.D.=0.81).	3) Knowledge and emerging skills: it was found that electronic technology for the intelligent environment had the highest need (PNI_modified = 0.36), and emotional skills (Soft Skills) found that the skill of quantitative and statistical analysis at first order.
The Decision Making of Textile Chock Tai-Yuan on Purchasing of Tourists in Ratchaburi Province
Authors:   Faculty of Home Economics Technology, Rajamangala University of Technology Phra Nakhon, Chuangcherm Supasun , Kee-ariyo Chayapat ,   Rajamangala University of Technology Phra Nakhon
Published: December 2022

The purposes of this research are: 1) to study the personal factors of tourists in Ratchaburi province ,2) to study the factors of marketing mix are using in the decision to buy Textile Chock Thai-Yuan cloth among tourists in Ratchaburi Province , 3) to study the decision to buy Textile Chock Thai-Yuan fabric among tourists in Ratchaburi Province, 4) find a relationship between personal factors and the decision to buy Textile Chock Thai-Yuan are clothing among tourists in Ratchaburi Province, and 5) find the relationship between the marketing mix and the decision to buy Textile Chock Tai-Yuan cloth of tourists in Ratchaburi Province. The sample are tourists who decide to buy Textile Chock Tai-Yuan In Ratchaburi, 400 people.The instruments are using in research questionnaires. The statistics are using for data analysis frequency, percentage, mean, standard deviation, and Chi-square and Pearson's Simple Correlation Coefficient Statistics.	The research was found that as follows: 1) tourist most of them were female, about 41-50 years old with a bachelor's degree in government service, state enterprise employees or university staff. The income was approximately 20,001 - 25,000 baht and was domiciling in Ratchaburi Province. 2) Tourists were paying attention to the factors of marketing mix Very level. When considered on a particular side, in descending order, namely products, personnel, price, processes physical characteristics, marketing promotion, distribution channel. 3) Tourists were judging on the level of not sure what to buy. When considered on a particular side, in descending order, namely. The type of Textile Chock Tai-Yuan opportunities were for using. Objectives were for purchasing decisions pattern of the selected cloth, average cost per time and the frequency was buying Textile Chock Tai-Yuan Fabrics. 4) The relationship between personal factors and the decision were to buying textile Chock Thai-Yuan Cloth among tourists in Ratchaburi Province were found that gender, age, highest education level, occupation, average monthly income and domicile were relating to the decision to buy Textile Chock Thai-Yuan Clot in Ratchaburi Province with statistical significance at the .05 level. And 5) relationship between marketing mix and decision to buy Textile Chock Tai-Yuan Fabric among tourists in Ratchaburi Province. Which were found that the marketing mix factor of distribution channel price marketing promotion, personnel, process physical characteristics. They were relating except marketing mix factors, product aspect. There was no relationship with the decision to buy Textile Chock Thai-Yuan Cloth in Ratchaburi Province with statistical significance at the .05 level.
ANALISIS BUKTI DIGITAL PADA RANDOM ACCESS MEMORY ANDROID MENGGUNAKAN METODE LIVE FORENSIC KASUS PENJUALAN SENJATA ILLEGAL
Authors: Yahya Arjun Zakari , Dirman  , Buru Dadang Juwoto , Sugiantoro Bambang 
Published: December 2022

Metode Live forensic adalah analisis data yang berjalan langsung pada bagian Random Access Memory. Tempat penyimpana sementara disebut juga Random Access Memory, data yang ada tersimpan di dalam Random Access Memory sifatnya adalah volatile atau mudah menghilang. Tujuan dari penelitian ini akan mendapatkan hasil bukti berupa digital melalui cara analisis bukti digital pada random access memory pada smartphone android pelaku dan smartphone korban menggunakan metode live forensic dalam kasus penjualan senjata illegal. Pada penelitian barang bukti digital yang disita berupa smartphone pelaku maupun smartphone korban. Korban diposisi sebagai mahasiswa yang ditawari untuk membeli senjata ilegal oleh pelaku. Metode analisis data yang dilakukan menggunakan metode NIST (National Institute Of Standart Technology) yang memiliki langkah-langkah analisis berupa preservation, acquisition, examination, analysis dan reporting. Data yang diambil dari random access memory berupa log file telephone, sms, dan data dari whatsapp. FTK (Forensic Tool Kit) digunakan untuk mencari bukti-bukti digital kejahatan penjualan senjata illegal. Hasilnya berupa bukti kejahatan yang telah dihapus oleh pelaku, antara lain bukti log telephone, sms, chat whatsapp, dan file gambar berekstensi .jpg. Memtools sangat berguna untuk mendapatkan data dari random access memory secara menyeluruh.
ANALISIS FORENSIK TERHADAP SERANGAN DDOS PING OF DEATH PADA SERVER
Authors: - Muhammad Adam , Alwi Erick Irawadi , As’ad Ihwana 
Published: December 2022

Abstrak
Kemajuan teknologi yang terus berkembang bisa menjadi sebuah ancaman salah satunya pada bidang dunia maya dimana terdapat beberapa kejahatan cyber dengan caranya yaitu menurunkan kinerja web server Anda dengan membanjiri lalu lintas jaringan. Terlepas dari apa telah Anda lakukan untuk meningkatkan kinerja web server Anda, peretas masih dapat mensimulasikan lebih banyak pengguna daripada yang dapat ditangani oleh web server itu sendiri. Pada data IDSIRTI bulan oktober 2020 total serangan mencapai 66 juta dan serangan DDoS dilakukan berdasarkan klasifikasi anomali mencapai 6 juta serangan. Peningkatan ancaman dan serangan terhadap keamanan sistem meningkat karena didukung oleh kemudahan akses dan ketersediaan sumber daya yang lebih mudah didapatkan. Banyak tahapan yang dapat dilakukan pelaku kejahatan cyber untuk memuluskan langkahnya mendapatkan informasi sebanyak mungkin pada target salah satunya adalah DDoS. Untuk memuluskan langkahnya biasanya dilakukan dengan menggunakan metode untuk membanjiri source pada perangkat jaringan. Web server merupakan salah satu bagian dari sebuah jaringan dan seiring jalanya perkembangan zaman banyak sekali web yang tersebar atau bertebaran di internet dan bisa diakses, serangan intrusi sangat tidak diinginkan pada sistem karena bisa membahayakan kerahasiaan dan ketersediaan sumber daya yang ada jenis serangan terhadap sebuah web server menghabiskan sumber (resource) yang dimiliki.Masalah datang dimulai ketika paket data yang datang sangat banyak dan harus di analisis terhadap sebuah data. Pada penelitian ini akan melakukan sebuah serangan DDOS Ping Of Death pada sebuah web server yang dimana hasil dari sebuah penyerangan tersebut akan menciptakan data record yang terekam pada software snorby, data tersebut dibutuhkan untuk menjalankan forensik agar dapat mengumpulkan bukti digital dengan menggunakan metode forensik (NIST) yang meliputi collection,examination,analysis,reporting. Berdasarkan dari percobaan pengujian tahapan pemeriksaan menghasilkan bukti data oleh snorby tahapan analisis mendapatkan adanya serangan yang dilakukan oleh alamat IP 192.168.177.2 dengan jenis serangan DDOS Ping Of Death dan menyerang web server dengan alamat IP 103.229.73.105.
Kata kunci: Web Server,Forensic,NIST, DDoS, Ping Of Death
Mechanisms of Administrative Offenses of Minors
Authors: Karipbaev Zhasulan , Bozhkarauly Altay 
Published: December 2022

The mechanism of illicit behavior of minors in administrative offenses has a complex morphological footprint. In its essence, it involves not only the administrative action itself, but also its direct causes, that are the necessary attributes of the offense, that are presented in the form of administrative representation, that is the subject to administrative responsibility. It goes without saying that in this case, it should be remembered that in the case of administrative law, there are alternative measures to minimize administrative incentives by juvenile delinquents in terms of administrative responsibility.
Thus, it is obvious that no external act of conscious behavior will be by itself or spontaneously; it is almost always ready for a long-term period of motivation, action planning and decision-making on action that arises sooner or later. As a rule, before this kind of act, the complex functioning of the mental function of the subject gradually forms the direction of action and its actual implementation. At the same time, the environment of the juvenile as well as the circumstances in which he or she lives are of great importance.
Problems of Implementation of the United Nation Convention Against Corruption in Kazakhstan Legislation
Authors: KHASSENOVA Almagul , KUDRYAVTSEVA Anna , MASHABAEYV Amanbec , UALIYEVA Zhanna , SHAKENOV Denis 
Published: December 2022

In the modern period, the objective factor is the awareness of humanity of its unity in solving global problems. One of these problems is the implementation of joint actions by states in the field of combating corruption. There is no doubt that the achievement of this goal should be based on international conventions adopted in accordance with generally accepted principles and norms of international law.
The world community is aware of the danger of corruption and is taking effective steps to consolidate efforts against this global threat. In modern international law, an institution of cooperation in the fight against corruption has been formed. The norms of this institution determine the basic signs of corruption and corruption offenses, determine the range of subjects of corruption, establish the rules for the exercise of jurisdiction, and provide for forms of cooperation and measures of assistance and legal assistance.