bluuebunny/crossref_metadata_2025_split huggingface dataset:
A systematic bibliometric analysis of studies dealing with fuel-related e-nose applications
Authors: Vidigal Igor Gomes , de Melo Mariana Pereira , Siqueira Adriano Francisco , Giordani Domingos Sávio , Romão Érica Leonor , dos Santos Eduardo Ferro , Ferreira Ana Lucia Gabas 
Published: December 2022

PurposeThis study aims to describe a bibliometric analysis of recent articles addressing the applications of e- noses with particular emphasis on those dealing with fuel-related products. Documents covering the general area of e-nose research and published between 1975 and 2021 were retrieved from the Web of Science database, and peer-reviewed articles were selected and appraised according to specific descriptors and criteria.Design/methodology/approachAnalyses were performed by mapping the knowledge domain using the software tools VOSviewer and RStudio. It was possible to identify the countries, research organizations, authors and disciplines that were most prolific in the area, together with the most cited articles and the most frequent keywords. A total of 3,921 articles published in peer-reviewed journals were initially retrieved but only 47 (1.19%) described fuel-related e-nose applications with original articles published in indexed journals. However, this number was reduced to 38 (0.96%) articles strictly related to the target subject.FindingsRigorous appraisal of these documents yielded 22 articles that could be classified into two groups, those aimed at predicting the values of key parameters and those dealing with the discrimination of samples. Most of these 22 selected articles (68.2%) were published between 2017 and 2021, but little evidence was apparent of international collaboration between researchers and institutions currently working on this topic. The strategy of switching energy systems away from fossil fuels towards low-carbon renewable technologies that has been adopted by many countries will generate substantial research opportunities in the prediction, discrimination and quantification of volatiles in biofuels using e-nose.Research limitations/implicationsIt is important to highlight that the greatest difficulty in using the e-nose is the interpretation of the data generated by the equipment; most studies have so far used the maximum value of the electrical resistance signal of each e-nose sensor as the only data provided by this sensor; however, from 2019 onwards, some works began to consider the entire electrical resistance curve as a data source, extracting more information from it.Originality/valueThis study opens a new and promising way for the effective use of e-nose as a fuel analysis instrument, as low-cost sensors can be developed for use with the new data analysis methodology, enabling the production of portable, cheaper and more reliable equipment.
Spatiotemporal thermal variation drives diversity trends in experimental landscapes
Authors: Wolfe Ellie , Cerini Francesco , Besson Marc , O'Brien Duncan , Clements Christopher F. 
Published: December 2022

Abstract

Temperature is a fundamental driver of species' vital rates and thus coexistence, extinctions and community composition. While temperature is neither static in space nor in time, little work has incorporated spatiotemporal dynamics into community‐level investigations of thermal variation.

We conducted a microcosm experiment using ciliate protozoa to test the effects of temperatures fluctuating synchronously or asynchronously on communities in two‐patch landscapes connected by short or long corridors.

We monitored the abundance of each species for 4 weeks—equivalent to ~28 generations—measuring the effects of four temperature regimes and two corridor lengths on community diversity and composition.

While corridor length significantly altered the trajectory of diversity change in the communities, this did not result in different community structures at the end of the experiment. The type of thermal variation significantly affected both the temporal dynamics of diversity change and final community composition, with synchronous fluctuation causing deterministic extinctions that were consistent across replicates and spatial variation causing the greatest diversity declines.

Our results suggest that the presence and type of thermal variation can play an important role in structuring ecological communities, especially when it interacts with dispersal between habitat patches.
Patterns, sources, and consequences of variation in age‐specific vital rates: Insights from a long‐term study of Weddell seals
Authors: Rotella Jay J. 
Published: December 2022

Abstract

Variations in the reproductive and survival abilities of individuals within a population are ubiquitous in nature, key to individual fitness, and affect population dynamics, which leads to strong interest in understanding causes and consequences of vital‐rate variation. For long‐lived species, long‐term studies of large samples of known‐age individuals are ideal for evaluating vital‐rate variation.

A population of Weddell seals in Erebus Bay, Antarctica, has been studied each Austral spring since the 1960s. Since 1982, all newborns have been tagged each year and multiple capture‐mark‐recapture (CMR) surveys have been conducted annually.

Over the past 20 years, a series of analyses have built on results of earlier research by taking advantage of steady improvements in the project's long‐term CMR data and available analytical methods. Here, I summarize progress made on four major topics related to variation in age‐specific vital rates for females: early‐life survival and age at first reproduction, costs of reproduction, demographic buffering, and demographic senescence.

Multistate modelling found that age at first reproduction varies widely (4–14 years of age) and identified contrasting influences of maternal age on survival and recruitment rates of offspring. Subsequent analyses of data for females after recruitment revealed costs of reproduction to both survival and future reproduction and provided strong evidence of demographic buffering. Recent results indicated that important levels of among‐individual variation exist in vital rates and revealed contrasting patterns for senescence in reproduction and survival.

Sources of variation in vital rates include age, reproductive state, year, and individual. The combination of luck and individual quality results in strong variation in individual fitness outcomes: ~80% of females born in the population produce no offspring, and the remaining 20% vary strongly in lifetime reproductive output (range: 1–23 pups).

Further research is needed to identify the specific environmental conditions that lead to annual variation in vital rates and to better understand the origins of individual heterogeneity. Work is also needed to better quantify the relative roles of luck, maternal effects, and environmental conditions on variation in vital rates and to learn the importance of such variation to demographic performance of offspring and on overall population dynamics.
The catalase‐peroxidase PiCP1 plays a critical role in abiotic stress resistance, pathogenicity and asexual structure development in Phytophthora infestans
Authors: Wang Tuhong , Lv Jia‐Lu , Xu Jianping , Wang Xiao‐Wen , Zhu Xiao‐qiong , Guo Li‐Yun 
Published: December 2022

AbstractCatalase‐peroxidase is a heme oxidoreductase widely distributed in bacteria and lower eukaryotes. In this study, we identified a catalase‐peroxidase PiCP1 (PITG_05579) in Phytophthora infestans. PiCP1 had catalase/peroxidase and secretion activities and was highly expressed in sporangia and upregulated in response to oxidative and heat stresses. Compared with wild type, PiCP1‐silenced transformants (STs) had decreased catalase activity, reduced oxidant stress resistance and damped cell wall integrity. In contrast, PiCP1‐overexpression transformants (OTs) demonstrated increased tolerance to abiotic stresses and induced the upregulation of PR genes in the host salicylic acid pathway. The high concentration of PiCP1 can also induced callose deposition in plant tissue. Importantly, both STs and OTs have severely reduced sporangia formation and zoospore releasing rate, but the sporangia germination rate and type varied depending on environmental conditions. Comparative sequence analyses show that catalase‐peroxidases are broadly distributed and highly conserved among soil–borne plant parasitic oomycetes, but not in freshwater‐inhabiting or strictly plants‐inhabiting oomycetes. In addition, we found that silencing PiCP1 downregulated the expression of PiCAT2. These results revealed the important roles of PiCP1 in abiotic stress resistance, pathogenicity and in regulating asexual structure development in response to environmental change. Our findings provide new insights into catalase‐peroxidase functions in eukaryotic pathogens.
The piRNA pathway is required for nucleopolyhedrovirus replication in Lepidoptera
Authors: Xia Junming , Fei Shigang , Wu Hongyun , Yang Yifan , Yu Wensheng , Zhang Mengmeng , Guo Yiyao , Swevers Luc , Sun Jingchen , Feng Min 
Published: December 2022

AbstractThe Piwi‐interacting RNA (piRNA) pathway has been shown to be involved in the antiviral defense against RNA viruses, especially in mosquitoes, but its universality has been questioned. Here, we used the Bombyx mori nucleopolyhedrovirus (BmNPV) ‐infected silkworm as a model to explore the effects of the key factors of piRNA pathway, BmAgo3 and Siwi, on replication of a large DNA virus (belonging to the family of Baculoviridae). We demonstrated that BmAgo3 and Siwi could promote the replication of BmNPV through both overexpression and knockdown experiments in BmN cell lines and silkworm larvae. In addition, we also studied the effect of PIWI‐class genes on Autographa californica nucleopolyhedrovirus (AcMNPV) replication in the Spodoptera frugiperda cell line Sf9. By knocking down the expression of PIWI‐class genes in Sf9, we found that Piwi‐like‐1 and Piwi‐like‐2‐3 could inhibit AcMNPV replication, while Piwi‐like‐4‐5 promoted virus replication. Our study provides compelling evidence that the piRNA pathway affects host infection by exogenous viruses in Lepidoptera. Also, our results reflect the diversity of the roles of PIWI‐class genes in virus infection of the host across species. This study is the first to explore the interaction of PIWI‐class proteins with DNA viruses, providing new insights into the functional roles of the piRNA pathway.
Policy Instruments to Support Agroecological Transitions in Europe
Authors: Gava Oriana , Povellato Andrea , Galioto Francesco , Pražan Jaroslav , Schwarz Gerald , Quero Alba Linares , Iragui Uxue Yoldi , Massa Carlos Astrain , Zīlāns Andis , Carolus Johannes 
Published: December 2022

SummaryAgroecological transitions have the potential to deliver multiple environmental and social benefits. However socio‐economic barriers have prevented those transitions in many European contexts. This article aims to inform policymakers about policy instruments that can foster agroecological transitions in Europe, especially by removing key socio‐economic barriers. A multi‐step methodology was carried out over a two‐year period in 15 case studies across Europe. The case studies represent farming systems that are in the process of initiating or enhancing the transition. Data collection relied on a participatory process, involving a variety of transdisciplinary actors. Study findings identify three major themes of barriers to agroecological transitions, namely actor capacity, value chain and policy. To address these barriers, policy instruments should consider the farming system’s stage in the transition pathway to take account of the different priorities of local actors. At the stage of initiating the transition, removing the barriers requires improvements in knowledge delivery mechanisms by strengthening advisory services and reducing decision‐makers’ uncertainty. At the stage of enhancing the transition, a focus on social capital is needed, for example by strengthening networking and cooperation measures. Generally, more attention towards state interventions which support the transitions to agroecology is needed, such as developing new voluntary agroecology certification schemes and public procurement initiatives.
The predictive value of the preoperative systemic immune‐inflammation index in the occurrence of postoperative pneumonia in non‐small cell lung cancer: A retrospective study based on 1486 cases
Authors: Jiang Rui , Li Pengfei , Shen Wang , Deng Hanyu , Qin Changlong , Qiu Xiaoming , Tang Xiaojun , Zhu Daxing , Zhou Qinghua 
Published: December 2022

AbstractBackgroundTo investigate the correlation between the preoperative systemic immune‐inflammation index (pSII) and postoperative pneumonia (POP) in surgical non‐small cell lung cancer patients.MethodsPatients who underwent lung cancer surgery at West China Hospital of Sichuan University were retrospectively included. The indicators were collected, including basic information of patients, surgery‐related variables and POP rate. The predictive value of the pSII in the occurrence of POP was analyzed.ResultsA total of 1486 patients (male: 748, 50.3%; female: 738, 49.7%; mean age: 58.2 ± 9.7 years; median age: 59 years old, interquartile range: 51–65 years old) were finally included in the study, of which 142 patients had POP with an incidence of 9.5% (142/1486), 9.2% (69/748) in males, and 9.9% (73/738) in females. The proportion of patients with diabetes in the pneumonia group was significantly higher than that in the nonpneumonia group (9.8%, 14/142 vs. 5.6%, 75/1344, p = 0.041). Compared with the nonpneumonia group, the level of the preoperative body mass index (24.2 [21.9, 26.1] vs. 23.1 [21.1, 25.2], p = 0.003) and SII (487 [350, 673] vs. 345 [230, 500], p < 0.001) in the pneumonia group were significantly higher. Multiple factor analysis showed that the pSII (odds ratio: 1.001, 95% confidence interval: 1.000–1.001, p < 0.001) was an independent risk factor for POP (487 [350, 673] vs. 345 [230, 500], p < 0.001); receiver operating characteristic curve analysis showed that the pSII was effective in predicting POP (area under curve: 0.751, p < 0.001).ConclusionThe pSII is closely related to and can effectively predict the occurrence of POP after lung cancer surgery.
Assessment of lymph node metastasis of ≤20 mm non‐small cell lung cancer originating from superior segment compared to basal segment
Authors: Yoshimura Ryuichi , Deguchi Hiroyuki , Tomoyasu Makoto , Shigeeda Wataru , Kaneko Yuka , Iwai Hidenobu , Saito Hajime 
Published: December 2022

AbstractBackgroundSegmentectomy with curative intention is occasionally performed for early non‐small cell lung cancer (NSCLC). However, a major problem has been pointed out, in that the rate of locoregional recurrence is higher after segmentectomy than after lobectomy. This study aimed to investigate differences in rates of lymph node metastasis between segment 6 and basal segment NSCLC as potential candidates for segmentectomy and to explore factors associated with locoregional recurrence of segmentectomy.MethodsWe retrospectively analyzed 461 patients with lower lobe NSCLC who underwent segmentectomy or lobectomy with mediastinal lymph node dissection between 2011 and 2021. Among these, 122 patients with clinical N0 NSCLC, diameter ≤ 20 mm, and consolidation tumor ratio >0.5 were analyzed.ResultsThe 122 patients were divided into a segment 6 group (n = 51) and a basal segment group (n = 71). Frequency of lymph node metastasis was significantly higher in the segment 6 group (17.7%) than in the basal segment group (4.2%; p = 0.01). Metastases to lymph node station 7 were seen in five of 122 patients (4.1%). Hilar lymph node metastasis occurred in nine of 122 patients (7.4%). Notably, metastases to station 11, 11i and 11 s lymph nodes were the most frequent patterns for hilar lymph nodes (41.7%).ConclusionsStation 11 lymph nodes are adjacent to the remaining lung segment or pulmonary artery in S6 segmentectomy or basal segmentectomy. Part of the NSCLC in segment 6 patients may thus be considered for lobectomy owing to the difficulty of complete dissection of station 11 lymph nodes.
Successful treatment with atezolizumab combination chemotherapy in a patient with high‐grade fetal adenocarcinoma of the lung: A case report
Authors: Fujimoto Kana , Watanabe Satomi , Yasuda Yuto , Date Emi , Kawabata Yasuhiro , Kanemura Hiroaki , Takahama Takayuki , Yonesaka Kimio , Iizuka Norishige , Takahashi Ken‐ichi , Kawakami Osamu , Ozaki Tomohiro , Nakagawa Kazuhiko 
Published: December 2022

AbstractHigh‐grade fetal lung adenocarcinoma (H‐FLAC) is a rare tumor, with little known of its response to chemotherapy with or without an immune checkpoint inhibitor or of its molecular profile. We report the first case of a 56‐year‐old man with stage IV H‐FLAC who was successfully treated with carboplatin plus nab‐paclitaxel in combination with atezolizumab. In addition, the tumor was found to be positive for amplification of the human epidermal growth factor receptor 2 gene.
A theoretical framework based on the needs of smart aged care for Chinese community‐dwelling older adults: A grounded theory study
Authors: Li Miao , Shen Jun , Wang Xinxia , Chen Qiu , Xiaoyan Liao , Ren Liu 
Published: December 2022

AbstractPurposeWith technological progress, the integration of aged care with technology is a new challenge. This study developed a theoretical model of smart aged care in the community to meet the diverse needs of community‐dwelling older adults.MethodsThis qualitative study recruited 22 participants from three communities in Chongqing, China. Through semi‐structured interviews and grounded theory, this study analyzed the needs of community‐dwelling older adults for smart aged care and identified strategies.ResultsNine categories were identified, including five need categories, three important factors, and one outcome objective. Furthermore, four health provider topics were proposed.ConclusionsAlthough the application of information technology has enhanced convenience and possibilities, its popularity and satisfaction are low. Information technology can be successfully introduced into the lives of community‐dwelling older adults only by truly understanding their needs.Implications of nursing practiceSmart aged care in the community has positive effects on nursing outcomes for older adults. This study's findings can help caregivers understand the various dimensions of the needs of community‐dwelling older adults and relevant influencing factors under smart aged care to increase its popularity and satisfaction. Furthermore, this can promote the integration of intelligent technology and manual services in nursing practice.
The effect of ketamine and fentanyl on haemodynamics during intubation in pre‐hospital and retrieval medicine
Authors: Ferguson Ian M. C. , Miller Matthew R. , Partyka Christopher , Bliss James , Aneman Anders , Harris Ian A. 
Published: December 2022

AbstractBackgroundKetamine use for rapid sequence intubation (RSI) is frequent in pre‐hospital and retrieval medicine (PHARM) and is associated with potentially deleterious haemodynamic changes, which may be ameliorated by concurrent use of fentanyl.ObjectivesTo describe the frequency with which fentanyl is used in conjunction with ketamine in a system where its use is discretionary, and to explore any observed changes in haemodynamics with its use.MethodsA retrospective observational study of over 800 patients undergoing RSI with ketamine ± fentanyl in the PHARM setting between 2015 and 2019. The primary outcome was the proportion of patients in each group who had a systolic blood pressure (SBP) outside a pre‐specified target range, with adjustment for baseline abnormality, within 10 min of anaesthetic induction.ResultsEight hundred and seventy‐six patients were anaesthetised with ketamine, of whom 804 were included in the analysis. 669 (83%, 95% CI 80%–86%) received ketamine alone, and 135 (17%, 95% CI 14%–20%) received both fentanyl and ketamine. Median fentanyl dose was 1.1 mcg/kg (IQR 0.75–1.5 mcg/kg). Systolic blood pressure (SBP) at induction was consistently associated with SBP after intubation in multivariable logistic regression, but fentanyl use was not associated with a change in odds of meeting the primary outcome (OR 1.08; 95% CI 0.72–1.60), becoming hypertensive (OR 1.35; 95% CI 0.88–2.07) or hypotensive (OR 0.76; 95% CI 0.47–1.21).ConclusionsThe addition of fentanyl to ketamine for RSI was not associated with an alteration of the odds of post‐induction haemodynamic stability, although the doses used were low. These findings justify further study into the optimal dosing of fentanyl during RSI in pre‐hospital and retrieval medicine.
The greening effects of regional innovation symbiosis – Evidence from Chinese listed firms
Authors: Liu Haiyue , Wang Cangyu , Zhang Qin , Zhao Changyi , Jiang Jie 
Published: December 2022

AbstractThis paper investigates the regional innovation symbiosis effect on firm green innovation. Chinese A‐share listed firms from 2012 to 2018 were the sample and the entropy method was used to construct a regional innovation symbiosis index. We found that innovation symbiosis significantly promoted firm‐level green innovation, with regional government environment investment playing an intermediary role. Further tests indicated that the effect was more pronounced when firms were in cities that had green industrial parks and in firms that publicly disclosed more environmental information. State‐owned firms were found to be more likely to focus on green innovation in higher innovation symbiosis systems.
Effect of a Veterans Health Administration mandate to case review patients with opioid prescriptions on mortality among patients with opioid use disorder: a secondary analysis of the STORM randomized control trial
Authors: Auty Samantha G. , Barr Kyle D. , Frakt Austin B. , Garrido Melissa M. , Strombotne Kiersten L. 
Published: December 2022

AbstractAimsThe Veterans Health Administration (VHA) implemented the Stratification Tool for Opioid Risk Mitigation (STORM) to reduce the risk of serious adverse events (SAE) among patients with opioid analgesic prescriptions. VHA facilities were mandated to case review patients identified as high risk by STORM. The aim of this study was to measure the effect of this mandate on all‐cause mortality and SAEs among VHA patients newly diagnosed with opioid use disorder (OUD).DesignSecondary analysis of a stepped‐wedged cluster randomized controlled trial conducted at all 140 VHA facilities, with facility as the unit of randomization, from 2018 to 2020.Setting and ParticipantsUnited States VHA facilities were randomized to case review the top 1 or 5% of high‐risk patients prescribed opioid analgesics identified by STORM. A total of 28 251 patients were diagnosed with OUD during the trial and were considered control or treatment depending on the status of the facility where they received their OUD diagnosis. Post‐hoc analyses among patients who had at least one opioid analgesic prescription in the 90 days prior to diagnosis were conducted and were then stratified by receipt of a prescription in the 90 days following diagnosis to assess the sensitivity of results to opioid discontinuation.MeasurementsAll‐cause mortality and opioid‐related, drug‐related, suicide‐related and other SAEs within 90 days of OUD diagnosis.FindingsMandated case review increased the odds of 90‐day mortality [odds ratio (OR) = 1.74, 95% confidence interval (CI) = 1.06, 2.87], but did not significantly change the odds of SAEs. Among patients who received an opioid prescription prior to but not after OUD diagnosis, the odds of all‐cause mortality within 90 days was 5.87 (95% CI = 1.85, 18.58) relative to control patients.ConclusionsVeterans Health Administration patients newly diagnosed with opioid use disorder experienced increased all‐cause mortality following expansion of a case review mandate for high‐risk patients prescribed opioids.