bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychosocial risk factors for low back pain in US workers: Data from the 2002–2018 quality of work life survey
Authors: Yang Haiou , Lu Ming‐Lun , Haldeman Scott , Swanson Naomi 
Published: November 2022

AbstractBackgroundExamining workplace psychosocial risk factors for back pain becomes increasingly important because of the changing nature of work and rising healthcare costs. Some psychosocial risk factors for back pain, such as work and family imbalance, exposure to a hostile work environment, and job insecurity, are understudied for the working population in the United States.MethodsData used in this study came from the Quality of Work Life Survey (QWL), a supplementary module of the General Social Survey conducted in the United States. Data from the 2002, 2006, 2010, 2014, and 2018 QWL surveys were used in these analyses, giving a total sample size of 6661. Five domains of workplace psychosocial risk factors for back pain were examined, including job strain, low social support, work‐family imbalance, exposure to a hostile work environment (harassment and discrimination), and job insecurity. The adjusted odds ratio (aOR) of each psychosocial risk factor for back pain with 95% confidence intervals (CI) was estimated using a multivariable logistic regression model after controlling for job physical factors, occupation, and demographic and socioeconomic characteristics.ResultsSignificant associations were found between back pain and several psychosocial factors including job strain (aOR 1.19; CI 1.00,1.41), work‐family imbalance (aOR,1.42; CI 1.22,1.64), harassment (aOR 1.40; CI 1.15,1.71), and discrimination (aOR 1.20 CI 1.00,1.44).ConclusionThis study contributes to the understanding of the relationship between a variety of workplace psychosocial factors and back pain. Our findings suggest directions in future longitudinal research to examine emerging workplace psychosocial factors for back pain.
Optimization of Chlorella vulgaris cultivation grown in waste molasses syrup using mixture design
Authors: Mohammadi Fahimeh Sadat , Arabian Daryush 
Published: November 2022

AbstractThe aim of this study was to determine and optimize culture media for Chlorella vulgaris microalgae under mixotrophic conditions using waste molasses as a cheap carbon source containing both organic carbons and other nutrients. In the current study, at first the growth and lipid productivity of C. vulgaris were assessed in different culture media and the best media was selected for mixotrophic growth conditions. Significant medium ingredients were screened through Plackett–Burman design. Then ingredients with positive effect were considered as a mixture component and their combinations were evaluated on lipid productivity using mixture design. According to results, Zarrouk medium was considered as the base medium with the highest biomass and lipid productivity of 72 and 7.1 mg L−1 d−1, respectively. Based on the Plackett–Burman design, out of 11 factors, molasses, NaNO3 and K2HPO4 demonstrated key roles in biomass and lipid productivity in mixotrophic conditions. Consequently, the selected three factors were investigated by mixture design. The results showed that high concentration of molasses causes decrease in biomass and lipid productivity due to high turbidity and a blend consisting of approximately 9.5 g L−1 molasses, 5 g L−1 NaNO3 and 0.15 g L−1 K2HPO4 was found as the optimum mixture with obtained lipid productivity of 115 mg L−1 d−1. In conclusion, waste molasses can be used as a promising feedstock for cost effective cultivation of C. vulgaris.
Oxidation of lubricating oil and its influence on the aging behaviors of fluorine rubber
Authors: Yang Guo , Wang Qilong , Zhuo Wenyue , Li Gao , Niu Yanhua , Li Guangxian 
Published: November 2022

AbstractFluoroelastomer (FKM) has been widely used in aerospace and some particular fields, whose aging is a key problem to influence the service life of the systems. The aging behaviors of FKM in the lubricating oil have been investigated in our previous study. In this work, the influence of intentionally aged or oxidized lubricating oil (A‐O) on the aging process of FKM is reported for the first time comparing with the situation in the fresh oil (F‐O). As the oil medium aged at 200°C for different time, its color, acid number and contact angle with FKM change evidently indicating possible oxidation might occur although the Fourier transform infrared spectrometer (FTIR) has little change. Then, the influence of aged oil medium on the aging behaviors of FKM was further examined. Compared with F‐O, the aging process of FKM in A‐O was significantly accelerated as evidenced by FTIR, tensile strength, mass change, DMA, and macroscopic observation. With the increase of aging temperature from 150 to 200°C, the contrast between A‐O and F‐O conditions become more prominent. Specifically, at 200°C, the crosslinking density and tensile strength of FKM in A‐O decreased by 2.2 × 10−4 mol/cm3 and 2.5 MPa compared to that in F‐O, and the mass change reached to 3.8%, which might be due to the higher amount of oil medium by diffusion into the FKM matrix.
Visible‐Light‐Promoted Catalyst‐Free Oxyarylation and Hydroarylation of Alkenes with Carbon Dioxide Radical Anion
Authors: Hou Jing , Hua Li‐Li , Huang Yan , Zhan Le‐Wu , Li Bin‐Dong 
Published: November 2022

AbstractVisible‐light‐mediated oxyarylation and hydroarylation of alkenes with aryl halides using formate salts as the reductant and hydrogen source under ambient conditions were developed. These protocols represent rare catalyst‐free examples of the realization of such transformations. Using styrenes as substrates, oxyarylation could occur smoothly. Whereas, hydroarylation proceeds employing electron deficient alkenes. Moreover, dehalogenation proceeds successfully in the absence of alkenes. We expected that this method could provide a valuable strategy for the functionalization of aryl halides.
Strange stars confronting with the observations: Non‐Newtonian gravity effects, or the existence of a dark‐matter core
Authors: Pi Chun‐Mei , Yang Shu‐Hua 
Published: November 2022

AbstractWe find that the existence of strange stars is ruled out by the dimensionless tidal deformability of a star of GW170817 and the mass of PSR J0740 + 6620, both for the standard MIT bag model and for the density‐dependent quark mass model. However, if non‐Newtonian gravity effects are considered, strange stars can exist for certain ranges of the values of the non‐Newtonian gravity parameter. An alternative explanation to these observations is to suppose that strange stars in GW170817 have a dark‐matter core.
MET kinase inhibitor reverses resistance to entrectinib induced by hepatocyte growth factor in tumors with NTRK1 or ROS1 rearrangements
Authors: Takumi Yohei , Arai Sachiko , Suzuki Chiaki , Fukuda Koji , Nishiyama Akihiro , Takeuchi Shinji , Sato Hiroki , Matsumoto Kunio , Sugio Kenji , Yano Seiji 
Published: November 2022

AbstractBackgroundEntrectinib is an effective drug for treating solid tumors with NTRK gene rearrangement and non‐small cell lung cancer (NSCLC) with ROS1 gene rearrangement. However, its efficacy is limited by tolerance and acquired resistance, the mechanisms of which are not fully understood. The growth factors produced by the tumor microenvironment, including hepatocyte growth factor (HGF) produced by tumor‐associated fibroblasts, critically affect the sensitivity to targeted drugs.MethodsWe investigated whether growth factors that can be produced by the microenvironment affect sensitivity of NTRK1‐rearranged colon cancer KM12SM cells and ROS1‐rearranged NSCLC HCC78 cells to entrectinib both in vitro and in vivo.ResultsAmong the growth factors assessed, HGF most potently induced entrectinib resistance in KM12SM and HCC78 cells by activating its receptor MET. HGF‐induced entrectinib resistance was reversed by the active‐HGF‐specific macrocyclic peptide HiP‐8 and the MET kinase inhibitor capmatinib in vitro. In addition, HGF‐producing fibroblasts promoted entrectinib resistance in vitro (culture model) and in vivo (subcutaneous tumor model). The use of capmatinib circumvented entrectinib resistance in a subcutaneous tumor model inoculated with KM12SM and HGF‐producing fibroblasts.ConclusionOur findings suggest that growth factors in the tumor microenvironment, such as HGF, may induce resistance to entrectinib in tumors with NTRK1 or ROS1 rearrangements. Our results further suggest that optimally co‐administering inhibitors of resistance‐inducing growth factors may maximize the therapeutic efficacy of entrectinib.
Inverted T‐shape free gingival graft for treatment of RT3 gingival recession defects: Reporting of two cases
Authors: Alrmali Abdusalam , Saleh Muhammad H. A. , Wang Hom‐Lay 
Published: November 2022

AbstractIntroductionOne of the most challenging aspects of treating gingival recession type 3 (RT3) is reconstructing lost interdental papillae, which is directly related to the loss of interproximal bone. Free gingival graft (FGG) has been successfully used to increase the keratinized tissue width (KTW) with minimal trauma to the interdental papilla. This presented case suggests that FGG can be used for reconstruction of lost initerdental papilla creeping attachment also plays an additional role in improving the results.Case PresentationThe included two case reports suggest a novel technique using an FGG that is shaped in an inverted T‐shape to achieve partial root coverage, improve the compromised interdental papilla, and increase the KTW in RT3 defects.ConclusionsThis report presents a novel yet intuitive surgical technique for partial coverage of RT3 defects and reconstruction of the interdental papilla.SummaryThe inverted T‐shape soft tissue graft may be a valuable technique for papillary reconstruction in the challenge of RT3 recessions.Key pointsWhy is this case new information?

Reporting innovative technique with the interproximal extension of the FGG that sutured lingually with the lingual marginal gingiva.
Improve interdental clinical attachment phenotype and height.
More predictable root coverage because of increased vascularized interproximal bed for the graft to be survived.
What are the keys to the successful management of this case?

Having at least 2mm interproximal space for graft survival.
Good Extension with proper fixation of the lingual part of the graft, and stabilization of the graft.
What are the primary limitations to success in this case?

limited capacity for perfusion and survival of the lingual extension due to limited vascularity.
More investigations are necessary to confirm the validity of this technique.
‘Mental Wealth’ and ‘Mental Fitness’: The discursive construction of mental health in the Australian news media during the COVID‐19 pandemic
Authors: Horwood Grace , Augoustinos Martha , Due Clemence 
Published: November 2022

AbstractIn this study, we analysed how the concept of ‘mental health’ was discursively constructed in the news media in Australia during the first year of the COVID‐19 pandemic. An approach informed by critical discursive psychology was employed to analyse a sample of 436 print and online articles published in daily newspapers between January 1 and December 31, 2020. Three main interpretative repertoires were identified in the data. Together, these repertoires functioned to construct mental health as an internal, individual reservoir of positive emotion, which individuals are responsible for building and maintaining. An ideological dilemma was also observed between mental health as an individual responsibility and mental health as a societal responsibility. This study demonstrates that a discourse of individual responsibility for mental health was prevalent in the news media in Australia, even amid the COVID‐19 pandemic, and highlights the need for communications about mental health to be designed in ways that increase understanding of the social determinants of mental health. Please refer to the Supplementary Material section to find this article's Community and Social Impact Statement.
Synthesis and Crystal Structure of a New RTH‐Type Precursor and Its Interlayer Expanded Zeolite
Authors: Zi Wenwen , Zhang Jun , Jiang Jingang , Qu Konggang , Tao Shuo , Zhang Junjun 
Published: November 2022

AbstractTwo dimensional zeolites have drawn a lot of attention due to their structural diversity and chemical composition, which can be used to obtain 3D zeolites, for which there is no direct synthesis. Here, a new layer silicate zeolite L was synthesized using the N, N‐dimethyl‐(2‐methyl)‐benzimidazolium as the organic structure‐directing agent (OSDA) in the presence of fluoride. Structure determination by single‐crystal X‐ray diffraction reveals that the pure silica precursor with five‐ring pores in the crystalline sheets is composed of the rth layer stacking along the (001) direction in an …AAAA… sequence with SDA+ cations and F− residing within the interlayer spaces. Variable temperature powder X‐ray diffraction (PXRD) results showed that the new layer could transform into a 3D RTH topology structure at 350 °C via 2D‐3D topotactic transformation. Furthermore, a new 3D zeolite material is obtained by treating the original layer with a diethoxydimethylsilane agent under hydrochloric acid condition (HCl−DEDMS). Based on the PXRD results and the original layer structure, the new 3D zeolite structure expanding the rth layer with another Si atom is constructed, which possesses a 10×8×6 channel system. It displays a high BET surface area of 188 cm3/g with an external surface area of 130 cm3/g. The structure and textural properties pave a way for potential catalytic applications. The research not only provides a new layered zeolite, broadening the 2D zeolite framework types, but also allows for the discovery of a new stable 3D zeolite expanding the RTH structure with Si atom, which hasn't been reported yet.
Fluorescence Turn‐on of Tetraphenylethylene Derivative by Transfer from Cyclodextrin to Liposomes, HeLa Cells, andE. coli
Authors: Masuda Kosuke , Omokawa Riku , Kawasaki Riku , Mise Yuta , Ooyama Yousuke , Harada Shogo , Shinoda Wataru , Ikeda Atsushi 
Published: November 2022

AbstractHerein, trimethyl‐β‐cyclodextrin (TMe‐β‐CDx) and γ‐cyclodextrin (γ‐CDx) could dissolve a tetraphenylethylene derivative (TPE−OH4) in water through high‐speed vibration milling. The fluorescence intensity of the TMe‐β‐CDx−TPE−OH4complex was much higher than that of the γ‐CDx−TPE−OH4complex, as the rotation of the central C=C double bond of TPE−OH4after photoactivation was inhibited in a smaller TMe‐β‐CDx cavity in comparison with the γ‐CDx cavity. In contrast, the fluorescence intensity of the γ‐CDx−TPE−OH4complex was very weak; nevertheless, it increased after the addition of liposomes due to the transfer of TPE−OH4from the γ‐CDx cavity to the lipid membrane as a “turn‐on” phenomenon. Furthermore, to apply temperature sensor, it was demonstrated that the fluorescence intensity in the liposomes depended on the phase‐transition temperature. By using the fluorescence turn‐on phenomenon, TPE−OH4could detect the presence of HeLa cells andE. coliby fluorescence.
Gas‐Phase Characterization of Hypervalent Carbon Compounds Bearing 7‐6‐7‐Ring Skeleton: Penta‐ versus Tetra‐Coordinate Isomers
Authors: Muramatsu Satoru , Ohshimo Keijiro , Shi Yuan , Kida Motoki , Shang Rong , Yamamoto Yohsuke , Misaizu Fuminori , Inokuchi Yoshiya 
Published: November 2022

AbstractIn this study, we afford explicit characterizations of the electronic and geometrical structures of recently reported hypervalent penta‐coordinate carbon compounds by using gas‐phase characterization techniques: photodissociation spectroscopy (PDS) and ion mobility‐mass spectrometry (IM–MS). In particular for a compound with moderately electron‐donating ligands, bearing p‐methylthiophenyl substituents, the coexistence of tetra‐ and penta‐coordinate isomers is confirmed, consistent with solution characterizations. It is in sharp contrast to the exclusive tetra‐coordinate form (with normal valence of the central carbon atom) in the single crystal. This suggests that a non‐polar environment makes the penta‐coordinate structure thermodynamically most stable. This delicate difference between the tetra‐ and penta‐coordinate structures, which depends on the environment, is a close reflection of the lower activation barrier of the SN2 reaction found in neutral solvent or gas‐phase reactions.
Cooperative Photochemical Reaction Kinetics in Organic Molecular Crystals
Authors: Morimoto Kohei , Kitagawa Daichi , Bardeen Christopher J. , Kobatake Seiya 
Published: November 2022

AbstractPhotoreactive molecular crystals have been intensively investigated as next‐generation functional materials. Changes in physicochemical properties are usually interpreted in terms of static pre‐ and post‐reaction molecular structures and packings determined by X‐ray structure analysis. However, to elucidate the dynamic properties, it is necessary to understand the dynamic nature of photochemical kinetics in crystals. Reaction dynamics in the crystal phase can be dramatically different from those in dilute solution because the local molecular environment evolves as the surrounding reactant molecules are transformed into products. In this Review article, we summarize multiple examples of photochemical reactions in the crystalline phase that do not follow classical kinetic behavior. We also discuss different theoretical methods that can be used to describe this behavior. This Review article should help provide a foundation for future workers to understand and analyze photochemical reaction kinetics in crystals.
Energy savings bottleneck diagnosis of cooling system based on integrated correlation analysis
Authors: Zhu Xiaochen , Cui Jiangtao , Li Yong 
Published: November 2022

AbstractThe circulation cooling system is an important auxiliary system in industry and has great potential for saving energy. However, a holistic energy savings retrofit of the system can cause high costs and a low input–output ratio. To address this problem, this paper integrates grey correlation analysis and partial correlation analysis to propose a new energy savings bottleneck diagnosis method for the circulating cooling system. This method deeply analyzes the operation mechanism of the industrial circulating cooling system and summarizes the main energy‐savings factor. Through the energy savings bottleneck diagnosis method based on grey correlation analysis and partial correlation analysis, the energy savings correlation coefficient and energy savings difference coefficient are calculated, and the relationship between each energy savings factor and the specific energy consumption is accurately described and quantified. Furthermore, the system energy savings bottleneck diagnosis is performed and the quantified energy savings priority of each system link is obtained. It can effectively guide the implementation of system energy savings optimization and retrofit. Finally, the effectiveness of the diagnosis method is demonstrated by simulation verification with actual network data.
Exploring the Far Side of Glycosyl Sulfoxide Activation Process
Authors: Chen Wei , Wu Pinru , Zeng Jing , Fang Jing , Liao Zhiwen , Cai Lei , Wang Hao , Meng Lingkui , Wan Qian 
Published: November 2022

Comprehensive SummaryThe discovery of Kahne glycosylation forwards a big step in the carbohydrate chemistry. Despite an extensive series of studies, the precise mechanism of this powerful glycosylation is still not fully understood. To address these 30‐year puzzles, the far side of Kahne glycosylation is explored in this study. After a series of control and tracking experiments, a number of important intermediates including glycosyl oxo‐sulfonium ion and sulfenic anhydride (Crich's intermediate) are suggested to be responsible for the complex reaction pathway. It also reveals that in addition to the conventional ionic glycosylation pathway, a novel free radical pathway is very likely to contribute to the various side‐and co‐products. This study provides further understanding of Kahne glycosylation, and it also sheds light on how to improve the efficiency of sulfoxide‐based glycosylation reactions.
In Silico Partial N2 to NH3 Conversion with a Light Atom Molecule
Authors: Mebs Stefan 
Published: November 2022

AbstractN2 can be stepwise converted in silico into one molecule NH3 and a secondary amide with a bond activator molecule consisting only of light main group elements. The proposed N2‐activating pincer‐related compound carries a silyl ion (Si(+)) center as well as three Lewis acidic (−BF2) and three Lewis basic (−PMe2) sites, providing an efficient binding pocket for gaseous N2 within the framework of intramolecular frustrated Lewis pairs (FLP). In addition, it exhibits supportive secondary P−B and F⋅⋅⋅B contacts, which stabilize the structure. In the PSi(+)−N−N−BP environment the N≡N triple bond is extended from 1.09 Å to remarkable 1.43 Å, resembling a N−N single bond. The strongly activated N−N‐fragment is prone to subsequent hydride addition and protonation steps, resulting in the energy efficient transfer of two hydrogen equivalents. The next hydride added causes the release of one molecule NH3, but leaves the ligand system as poisoned R3Si(+)−NH2−PMe2 or R3Si(+)−NH3 dead‐end states behind. The study indicates that approximately tetrahedral constrained SiBP2‐pockets are capable to activate N2, whereas the acid‐rich SiB3‐ and SiB2P‐pocktes, as well as the base‐rich SiP3‐pockets fail, hinting towards the high relevance of the acid‐base proportion and relative orientation. The electronic structure of the N2‐activated state is compared to the corresponding state of a recently published peri‐substituted bond activator molecule featuring a PSi(+)−N−N−Si(+)P site (S. Mebs, J. Beckmann, Physical Chemistry Chemical Physics 2022, 24, 20953–20967).
Coding Synthetic Chemistry Strategies for Furan Valorization into Bacterial Designer Cells**
Authors: Liu Yu‐Chang , Wu Zhong‐Liu , Deska Jan 
Published: November 2022

AbstractFollowing a synthetic chemistry blueprint for the valorization of lignocellulosic platform chemicals, this study showcases a so far unprecedented approach to implement non‐natural enzyme modules in vivo. For the design of a novel functional whole cell tool, two purely abiotic transformations, a styrene monooxygenase‐catalyzed Achmatowicz rearrangement and an alcohol dehydrogenase‐mediated borrowing hydrogen redox isomerization, were incorporated into a recombinant bacterial host. Introducing this type of chemistry otherwise unknown in biosynthesis, the cellular factories were enabled to produce complex lactone building blocks in good yield from bio‐based furan substrates. This whole cell system streamlined the synthetic cascade, eliminated isolation and purification steps, and provided a high degree of stereoselectivity that has so far been elusive in the chemical methodology.