bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cerebroplacental ratio as a predictor of perinatal outcomes in intrauterine growth restriction
Authors: Thomas Susan , Menon Prameela , Madhu Indu M 
Published: November 2022

Intrauterine growth restriction (IUGR) complicates 7-15% of pregnancies and is associated with adverse perinatal outcomes. The primary goal of antenatal care is the early detection of such conditions. Doppler studies in fetus are used to predict the morbidity in IUGR. Studies show that cerebroplacental ratio is a better predictor of IUGR babies and adverse perinatal outcome. In this study we compare perinatal outcomes of IUGR babies with a normal CPR and an abnormal CPR. This prospective cohort study was carried out in the Department of Obstetrics and Gynaecology, Amala Institute of Medical Sciences, Thrissur, from January 2018 to June 2019. The study included 170 antenatal mothers diagnosed IUGR sonologically or are at risk of IUGR. CPR was calculated from Doppler parameters as ratio of MCA PI and Umbilical artery PI. CPR more than 1.08 was considered normal. Perinatal outcomes were compared between normal and abnormal CPR group. The incidence of abnormal CPR was found to be 39.4%. An abnormal CPR was associated with an increase in rate of emergency ceaserean rate for fetal distress (76.12%) and 64.18% had an APGAR of &#60;7 at 5 mts of life. 97.02% babies with an abnormal CPR were admitted to NICU for several reasons. Frequency of adverse perinatal outcomes was increased in abnormal CPR group. These differences were statistically highly significant. In patients with IUGR, cerebroplacental ratio is a useful marker in prediction of adverse perinatal outcome. Integrating CPR into routine Doppler studies in clinical practice will help better identify fetuses at risk.
Role of TVS and MRI imaging in perimenopausal bleeding
Authors: Goti Jaykumar D , Chudasama Nirmala C , Patel Kinjalben R , Prajapati Bhagyesh V 
Published: November 2022

Abnormal uterine bleeding is any variation in the normal menstrual cycle, Includes: changes in frequency, duration and amount of blood loss during or in between the cycles. Approximately 70% of all gynecological consultations in perimenopausal and postmenopausal women are for abnormal uterine bleeding. There complaints may significantly affect the quality of life and lead to surgical intervention. TVS is an inexpensive, non-invasive, easly available and a convenient method to assess the uterine pathology. It is recommended as the 1st line diagnostic tool for assessing uterine pathology in perimenopausal age women presenting with abnormal uterine bleeding.To differentiate and characterize uterine and ovarian lesions based on MRI and TVS findings. To identify organ of origin of uterine and ovarian lesions based on MRI and TVS findings. To diagnose pathologies which have a difficulty in detection with TVS.40 patients in perimenopausal age group with complain of abnormal uterine bleeding were subjected to TVS and MRI examination. Final correlation with histopathology was done wherever it was acquired.Among 40 females, majority of them were in pre menopause period 25 (62.5%) and the rest in the post menopause period 15(37.5%). Among 40, majority were diagnose fibroids 14(37.5%), adnexal lesions 11(27.5%), carcinoma of cervix 5(12.5%), endometrial lesions 6(12.5%)and adenomyosis 4(10.0%). Adnexal lesions start in early age itself (35±2). Endometrial lesions(51±8) and carcinoma of cervix(55±6) were reported mostly in the post menopausal periods. Fibroids (40±5)and Adenomyosis(42±4) were reported in middle age. Among 11 patients TVS diagnosed 4 as Complex Adnexal Cysts, 3 as Dermoid, 2 as Simple ovarian Cyst, 1 as haemorrhagic Cyst and 1 as Possibly hydrosalphinx and MRI diagnosed 3 as Complex Adnexal Cysts, 3 as Dermoid, 2 as Simple ovarian cysts, 2 as haemorrhagic cyst and 1 as Hydrosalphinx. MRI is found to be more accurate and precise in comparison to ultrasound to characterize, localize and evaluate the number of lesions both benign and malignant along with its staging in pelvic pathologies. While TVS lacks specificity and sensitivity in relation to MRI but acts as a great screening tool in evaluation and further management. MRI is accordingly a more precise preoperative imaging modality for portraying and distinguishing the distinct features of varied lesions.
To observe the rise in haemoglobin concentration levels by parenteral iron infusion of iron isomaltoside 1000 (Fur-IV) in gynaecological patients suffering from iron deficiency anaemia
Authors: Pandya Manish R , Patel Khushbu K 
Published: November 2022

Iron Isomaltoside 1000 (Fur-IV) is a combination of iron and isomaltoside 1000(carbohydrate) which are strongly bound allowing slow and controlled release thereby reducing risk of free iron toxicity and offers high dose flexibility and administration and convenience. It is shown to be effective in treating iron deficiency anaemia across multiple therapeutic groups and compared to IV iron sucrose, Ferric carboxymaltose, and oral iron. It is effective and well tolerated in treatment of anaemia across different therapeutic areas with favourable safety profile. To observe the rise in level of haemoglobin concentration in gynaecological patients suffering from iron deficiency anaemia via single infusion of iron isomaltoside 1000 (Fur-IV).A prospective, observational study.Total 50 women who were attending OPD or an indoor patient of obstetrics and gynaecology department who were diagnosed with iron deficiency anaemia and confirming to inclusion criteria were enrolled and observed in this study. Written and informed consent were taken from all patients and data were recorded in the case record form. Detailed medical history and iron demand of the patient were taken and calculated before administration of IV Iron Isomaltoside 1000 by our department of OBGY. Data of the patients who were enrolled in the study were recorded including their haemogram report before administration and repeat haemogram at 1 and 2 week after administration. We did the study from May, 2021 to June, 2022 in OBGY department of Scientific Research Institute, Surendranagar, Gujarat, India. There were no serious adverse events (AE) reported. Only 6 patients reported adverse events [mild nausea, vomiting n=2; fetal bradycardia, n=2; pruritus, n=1; giddiness, n=1. Mean change in Hb is evaluated in 50 patients, increased significantly from 8.63 ± 1.18 gm/dl at baseline to 10.74 ± 1.08 gm/dl (difference of 2.11 ± 0.77 gm/dl; p &#60; 0.001) at 2 weeks post-treatment. Safety and efficacy of Fur-IV was rated by physicians as ‘excellent and good’ in 98% patients.Iron isomaltoside 1000 (Fur-IV) has demonstrated robust efficacy in patients suffering from Iron deficiency anaemia due to pregnancy. The wide dosing range of Iron isomaltoside allows iron correction in a single visit with minimal risk of anaphylaxis and is thus cost‑effective for health‑care system.
Designing Standard Growth Chart Based on Weight-For-Age Z-Score of Children in East Java Using Least-Square Spline Estimator
Authors: Chamidah Nur , Kurniawan Ardi , Saifudin Toha 
Published: November 2022

Children would be categorized as children who have underweight nutritional status, if according to index of anthropometric they have a lack of weight. In Indonesia, this anthropometric index is recorded on a Card Toward Health called as KMS. This card follows the WHO-2005 standard which is designed based on samples from Brazil, Ghana, India, Norway, Oman, and USA. Those samples, of course, physically are very different from Indonesian children. Therefore, in this paper we design weight-for-age Z-score standard growth charts of children by using least-square spline estimator and samples of children from East Java province, Indonesia. Next, the proposed children standard growth charts are used to assess East Java children nutritional status. The results show that the proposed standard growth charts have met the goodness of fit criteria namely the average values of coefficient determination for boy and girl are close to one, and values of mean square errors are close to zero. It means that the proposed growth charts are more suitable to be used to assess the nutritional status of East Java children, because they can better explain the real conditions of children in East Java, Indonesia than the WHO-2005 standard growth charts.
Pelatihan Pembukuan Usaha Bagi Kelompok Pembudidaya Ikan Papuyu di Kampung Papuyu Kabupaten Banjar
Authors: Sofia Leila Ariyani , Zain Muhammad Adnan , Baturante Elmiwia Rani , Nor Ulya Israilah , Huda Nurul , Sari Dewi Ratna , Adeputra Muhammad Syawal 
Published: November 2022

Pengabdian Kepada Masyarakat ini bertujuan untuk memberikan pengetahuan dan keterampilan penyusunan pembukuan usaha kepada kelompok pembudidaya ikan papuyu. Metode yang diterapkan terdiri dari penyuluhan, pelatihan, dan evaluasi. Pelaksanaan pengabdian telah memberikan perubahan pengetahuan anggota pokdakan terhadap pembukuan usaha dari 19,15 (47,88%) meningkat menjadi 32,69 (81,73%). Kegiatan pengabdian juga meningkatkan kemampuan anggota pokdakan dalam menyusun pembukuan sederhana yang mudah mereka pahami sehingga pengoperasiannya dapat diseragamkan. Pembukuan yang diajarkan diharapkan dapat meningkatkan kemampuan produksi serta profitabilitas usaha yang dijalankan pokdakan di Desa Karang Intan Kabupaten Banjar.Kata kunci: bisnis, ikan papuyu, manajemen, pembukuan, pokdakan
Produção de spawns de Pleurotus sajor-caju com resíduos de cereais disponíveis ao sul do Tocantins
Authors: Menezes Ana Cristina de , Nunes dos Santos Thiago César , Da Silva Damiana Beatriz , De Souza Carlos Mourão Dalmarcia , Franke Portella Augustus Caeser 
Published: November 2022

Os fungos vêm acompanhando a humanidade desde a antiguidade, são organismos diferenciados, podendo viver no solo e na água e participam da ciclagem de nutrientes no ambiente. O objetivo desse trabalho é a produção de spawns, também conhecido como matriz ou sementes de cogumelos a partir de compostos residuais da agroindústria local ao Sul do Tocantins tais como, sorgo (Sorghum bicolor L. Moench) e milho (Zea mays) utilizados como substrato para a produção de cogumelos visando a a garantia da uniformidade da colonização e uma boa frutificação. Neste estudo foram usados micélios de Cogumelo Houbitake ou Ostra Cinza (Pleurotus sajor-caju FR. Singer). Os cereais não apresentaram diferença significativa no tempo de colonização, durante 13 dias de observações e cultivo, já na eficiência biológica, não houveram diferenças significativas entre os tratamentos, sendo que o sorgo mostrou um ganho de apenas 2% em relação ao milho, demonstrando a viabilidade para o cultivo.
Palavras-chave: Sorgo, Milho, Cogumelo houbitake
Research on the Effects of Welding Defects on the Strength Performance of Expandable Profile Liners and Approaches to Improve Welding Reliability
Authors: Zhao Le , Tu Yulin , Gao Mingzhong 
Published: November 2022

SummaryExpandable profile liner (EPL) technology (EPLT) provides an effective solution for lost circulation trouble control without wellbore diameter loss or sacrificing completion and production performance. However, the reliability and stability of the welding seams determine the overall bearing capacity of the EPL string. The application of EPLT in more complicated conditions requires increasing the overall performance of the EPL string welding seams. In this study, we considered four types of artificial welding defects, including cracks, pores, slag inclusions, and incomplete penetration in EPL string samples, and performed internal pressure limit tests to obtain the ultimate failure strength of EPL strings with different welding defects. Abaqus was used to quantitatively assess the influence of welding defects on the strength performance of the EPL string. The critical dimensions and safety evaluation curves of various defects, under a working pressure of 30 MPa (safety factor 1.5), were obtained using a combination of numerical simulations and experiments. Using the latest welding defect identification and detection methods and relevant evaluation procedures, the type, size, and position of welding defects in EPL string can be identified quickly. The new welding process and integrated automatic welding equipment improved the welding quality and reliability of the EPL string. The new research on EPL welding seam defects and recent advancements in EPLT can bring significant economic benefits, thus promoting the application of EPLT to meet future application challenges. The technical innovations presented in this study provide an effective solution for drilling engineering staff to solve the drilling troubles associated with lost circulation and borehole instabilities and are also conducive for oil companies to address the future challenges of exploitation and development of unconventional oil and gas resources.
Synaptotagmin-like protein 1 is a potential diagnostic and prognostic biomarker in endometrial cancer based on bioinformatics and experiments
Authors: Meijuan Cai , Meng Xu , Fang Liu , Qian Wang 
Published: November 2022

Abstract
Backgroud: Endometrial cancer (EC) is one of the most common gynecologic malignancies. Identification of potential EC biomarkers is essential to improve the prognosis and development of therapies against EC. Synaptotagmin-like protein 1 (SYTL1), as a small GTPase Rab27 effector, mainly plays a role in vesicle trafficking and cytotoxic granule exocytosis in lymphocytes. However the role of SYTL1 in EC remains uncertain. We performed a comprehensive assessment of the relationship between SYTL1 and patient diagnosis and prognosis by analysis of EC patients data from TCGA. We employed the LinkedOmics and Search Tool for the Retrieval of Interacting Genes/Proteins (STRING) database to analyze the biological function of SYTL1 in EC. In addition, the correlation between SYTL1 expression and its DNA methylation was performed by using cBioportal, UALCAN, TCGA Wanderer and MethSurv databases. We further assessed the link between SYTL1 and tumor-infiltrating immune cells by using gene set variation analysis (GSVA).
Results: We found that SYTL1 was highly expressed in EC patients and cell lines. And increased expression of SYTL1 was associated with age, clinical stage, histological type, histological grade and good overall survival (OS). SYTL1 DNA methylation is negatively associated with SYTL1 expression and UCEC patients’ OS. SYTL1 expression is closely correlated with immune infiltration. Furthermore, we carried out in vitro experiments to verify the results of bioinformatic analyisis. Conclusions: Our results demonstrated that the elevation of SYTL1 expression is associated with good OS and SYTL1 might be a potential diagnostic and prognostic marker in EC.
Ring Repeating Unit: A Deterministic Structure Representation of Polymers for Property Predictions
Authors: Yu Mengxian , Shi Yajuan , Jia Qingzhu , Wang Qiang , Luo Zheng-Hong , Yan Fangyou , Zhou Yin-Ning 
Published: November 2022

Abstract
Deterministic structure representation of polymers plays a crucial role in developing models for polymer property prediction and polymer design by data-centric approaches. Currently, unique structure representations of polymers, especially the polymers with heteroatomic backbones, are unavailable. In this contribution, we propose a so-called ring repeating unit (RRU) method that can uniquely represent polymers with a broad range of structure diversity. To prove the rationality of RRU-based structure representation for generating feature descriptors, a quantitative structure property relationship (QSPR) model for glass transition temperature (Tg) was established for 1321 polyimides with good accuracy (R2 = 0.8793). Comprehensive model validations including external, internal, and Y-random validations were performed, providing Tg prediction result with an average absolute error (AAE) of 19.38 ℃. It is believed that the as-developed RRU method allows for dealing with any macromolecular structure and targeted property, enabling for reliable polymer property prediction and high-performance polymer design by data-driven approaches.
Superior biological traits of invaded (Caribbean) versus native (Red Sea) populations of the seagrass Halophila stipulacea
Authors: Winters Gidon , Conte Chiara , Beca-Carretero Pedro , Nguyen Hung Manh , Migliore Luciana , Mulas Martina , Rilov Gil , Guy-Haim Tamar , González María J. , Medina Isabel , Golomb Dar , Kitson-Walters Kimani 
Published: November 2022

Abstract
The seagrass Halophila stipulacea is native to the Red Sea. It invaded the Mediterranean over the past century and most of the Caribbean over the last two decades. Understanding the main drivers behind the successful invasiveness of H. stipulacea has become crucial. We performed a comprehensive study including field measurements, a mesocosm experiment, and a literature review to identify ‘superior traits’ that can potentially explain the success story of H. stipulacea. We assessed meadow characteristics and plant traits of three invasive H. stipulacea populations growing off the Island of Sint Eustatius (eastern Caribbean). We compared similar parameters between native (Eilat, Red Sea) and invasive H. stipulacea plants in a common-garden mesocosm. Lastly, we also compared our field measurements with published data. The newly arrived H. stipulacea plants from St. Eustatius were characterized by higher percent cover, higher below- and above-ground biomasses, more apical shoots, and faster leaf turnover rates than those measured in both native and older invaded habitats. These results were further confirmed by mesocosm experiments where the invasive H. stipulacea plants grew faster and developed more apical shoots than the native plants. Results suggest that increased growth vigour is one of the main invasive traits that characterize successful invasive H. stipulacea populations in the Caribbean and potentially in other invaded areas. We encourage long-term monitoring of H. stipulacea in both native and invaded habitats to better understand the future spread of this species and its impacts on communities and their ecosystem functions and services.
Valve Block Flow Channel Planning Based On Additive Manufacturing And Ant Colony Algorithm
Authors: Li Ying , Li Ziyang , Zhang Yuying , Liu Yandong , Zhang Jin , Kong Xiangdong 
Published: November 2022

Abstract

Hydraulic valve block is an important part of aviation Electro-Hydrostatic Actuator (EHA). With the development of EHA in the direction of light weight and integration, the internal flow channel of the hydraulic valve block is required to be more compact. Based on the technical means provided by additive manufacturing technology, this paper adopts the Ant Colony Algorithm + B-spline curve to design the internal flow channel of the aviation EHA valve block, and realizes the automatic arrangement of the flow channel by computer. The flow characteristics of the flow channel before and after optimization are analyzed. The volume of the flow channel after optimization is reduced by , besides the pressure loss measured by the test is reduced by to . The feasibility of optimizing the design of flow channel by Ant Colony Algorithm and B-spline curve is verified, which provides a solution for flow channel design method based on additive manufacturing.
Spatio-temporal variation of in-cabin PM 2.5 levels in Metro Rolling Stock Saloons, Kochi Metro, South India
Authors: Akhilesh K. B. , Akhila T. , Madhuraj P. K. , Anjali T. B. , Anand M. 
Published: November 2022

Abstract
Increasing particulate matter (PM) especially PM2.5 (particles less than 2.5µm in aerodynamic diameter), pollution in the air-conditioned indoor microenvironment can spread infectious diseases such as Covid-19 on occupants in addition to respiratory and cardiovascular diseases. Given the importance of this subject in the contemporary social context, this study seeks to assess the spatiotemporal variation of PM2.5 concentration in Metro Rolling Stock (MRS) saloons of Kochi Metro Rail Limited (KMRL), Kerala, India. During the in-transit survey data was collected according to the four different plans depending on the time and direction of the metro service using a real-time Indoor Air Quality (IAQ) monitor. The spatial variation in PM2.5 content en-route 22 stations (Aluva to Petta) shows, Kalamassery Town station recorded the maximum value of 40.33µg/m3 and station Maharajas Ground recorded the lowest value of 23.95µg/m3 respectively. Comparing the median concentration of PM2.5 of the four plans implied that plan-1 (Aluva-Petta during morning peak hours) record the highest concentration than other plans (p-value < 0.05). Principal Component Analysis biplots, did not display strong positive associations among PM2.5 and the other in-transit variables such as temperature, relative humidity, carbon dioxide concentration, and the number of occupants. Therefore, the study infers that the infiltration of outdoor air when the doors are opened at each station could be the influencing factor of PM2.5 level in MRS saloons of KMRL. Moreover, the proximity to traffic signals, industrial establishments, and muncipal waste dumping sites increase the probability of PM2.5 level which was evident at Kalamassery Town station.
An all-37°C thawing method improves the clinical outcomes of vitrified frozen-thawed embryo transfer: a retrospective study using a case-control matching analysis
Authors: Yan Gaofeng , Yao Youlin , Yang Wenjuan , Lu Ling , Wang Longda , Zhao Di , Zhao Shuhua 
Published: November 2022

Abstract
Purpose
The purpose of this study is to assess the impact of different temperatures and equilibrium times on the clinical outcomes of FET cycles during the thawing procedure and to select a better thawing method to improve clinical outcomes.
Methods
This retrospective study included 1,734 FET cycles from January 1, 2020, to January 30, 2022. Embryos vitrified using a Kitazato Vitrification Kit were thawed at 37°C in all steps (the case group, denoted the “all-37°C” group) or at 37°C and then at room temperature (RT; the control group, denoted the “37℃-RT” group), according to the kit instructions. The groups were matched 1:1 to avoid confounding.
Results
After case-control matching, 366 all-37°C cycles and 366 37℃-RT cycles were included. The baseline characteristics were similar (all P > 0.05) between the two groups after matching. FET of the all-37°C group yielded a higher clinical pregnancy rate (CPR; P = 0.009) and implantation rate (IR; P = 0.019) than FET of the 37℃-RT group. For blastocyst transfers, the CPR (P = 0.019) and IR (P = 0.025) were significantly higher in the all-37°C group than in the 37℃-RT group. For cleavage embryo transfers, the CPR and IR were non-significantly higher in the all-37°C group than in the 37℃-RT group (P > 0.05).
Conclusions
Thawing vitrified embryos at 37°C in all steps during FET cycles can enhance CPR and IR. Well-designed prospective studies are warranted to further evaluate the efficacy and safety of the all-37°C thawing method.