bluuebunny/crossref_metadata_2025_split huggingface dataset:
Therapeutic efficacy of time-dependent cetuximab on experimentally induced hamster buccal pouch carcinoma
Authors: Shamia Ashraf Yehia Mohamed , Abd-Alhafez Abd-Alshakor , Al-qalshy Emad Soliman , Zouair Mohamed Gomaa Attia 
Published: July 2022

Purpose: This study aimed to determine the cetuximab therapeutic potential in the time-dependent fashion in experimentally induced hamster buccal pouch (HBP) carcinoma. Material and methods: Forty Syrian male hamsters were classified into four equal groups (G) of ten each. GI: The animals remained untreated to act as negative controls. The right pouches of animals in GII, GIII, and GIV were painted three times a week for 14 weeks (w)s with 7,12-dimethylbenz (a) anthracene (DMBA). GII: No additional treatment was administered. While, the animals in GIII and GIV were treated differently. Those in GIII received cetuximab intraperitoneally (IP) three intervals a week for three (w)s, whereas those in GIV received cetuximab IP three intervals for six (w)s. After the end of the experiment, the gross observations were made, and blood samples (2ml) were withdrawn from the inner canthus of the eye for analysis of whole white blood cells (WBCs) and oxidative stress markers [glutathione (GSH) and malondialdehyde (MDA) levels]. All pouches were surgically bisected for preparation for Hematoxylin and Eosin (H&E) stain and immunohistochemistry (IHC) stain using epidermal growth factor receptor (EGFR). Other fresh tissue was used for DNA detection through a flow cytometry (FCM) test.
Gerencia universitaria: una aproximación al funcionamiento estratégico de las dimensiones: docencia, investigación y extensión
Authors: Morales Jesús 
Published: July 2022

Esta investigación es el resultado de una revisión documental, cuyo objetivo fue la integración de varias perspectivas disciplinares en torno a la gerencia universitaria, como el proceso que debe guiar, impulsar y motorizar la formación competitiva de ciudadanos, con la flexibilidad para afrontar los desafíos de un mundo globalizado y en cambio recurrente. Además de tomar decisiones estratégicas y convertirse en agentes activos, comprometidos con la transferencia del conocimiento científico producido en la Universidad al escenario social, logrando de este modo maximizar las condiciones de bienestar y calidad de vida.
En conclusión, enfrentar los desafíos de un mundo globalizado, competitivo y permeado por el dinamismo y la progresividad, sugiere estrechar vínculos interactivos sociedad-Universidad en los que se logren diversificar las oportunidades de crecimiento multidimensional; y ampliar las posibilidades inclusivas como resultado de la disposición del conocimiento al servicio de la resolución de los problemas que aquejan a la humanidad.
A representação do Boi em uma estória de amor, de João Guimarães Rosa
Authors: Schtine Pereira Maria Viana 
Published: July 2022

Por meio deste ensaio, pretende-se demonstrar como o escritor João Guimarães Rosa dá voz ao contador de estórias seu Camilo, personagem da novela “Uma estória de amor”, do ciclo Corpo de Baile. Nesse sentido, estabelecerei relações entre as anotações e as imagens encontradas nos diários de viagem do escritor, com destaque para a presença do boi na cultura popular brasileira, para verificar em que medida pode-se estabelecer uma relação entre esse animal e a própria linguagem. Nesse percurso analítico, dialogarei com ideias de Derrida, apresentadas na obra A Farmácia de Platão, e conceitos sobre a memória, retomados por Paul Ricoeur do pensamento aristotélico.
International Arbitration and Enforcement of Arbitration Awards in Bahrain
Authors: Radhi Hassan Ali 
Published: July 2022

Since the formation in the mid-nineteenth century of Al-Majlis Al-Urfi as an international dispute resolution institution consisting of Bahraini and non-Bahraini members, Bahraini law makers have shown great concern for securing protection for foreign investors and commercial entities by developing laws and institutions governing dispute resolution in the fields of international trade and investment. Given the recent rapid economic development of the markets in the Middle East region, further development of laws on trade and investment has become imperative. Currently arbitration in Bahrain is governed by the Civil and Commercial Procedures Law and the International Commercial Arbitration Law, the latter of which is based upon the UNCITRAL Model Law. A new unified comprehensive law based on the UNCITRAL Model Law as amended in 2006 is expected to be promulgated soon. Furthermore, since Bahrain acceded to the New York Convention in 1988, Bahraini courts have enforced foreign arbitral awards. Bahrain is also party to other regional conventions in this respect. Despite these positive developments in Bahraini laws, there still exist some legislative and practical hindrances to arbitration and the enforcement of arbitral awards. This study introduces and analyzes the relevant laws governing arbitration in Bahrain, deals critically with the obstacles facing arbitration and suggests appropriate remedies to these hindrances.
International Arbitration and Its Users: Ships Passing in the Night? A Dialogue with Michael McIlwrath
Authors: Nappert Sophie 
Published: July 2022

If arbitration is a service industry, are users' expectations realistic? If it is market-driven, then why not more diversified appointments, given the wider pool of capable and talented arbitrators on the market? What is the purpose of the call for ethical guidelines, not only for arbitrators but for counsel? Is the market not adept at selecting the best candidates? What attributes make an arbitrator "the best"? If the arbitral process is party-led, why the spiraling upwards of time and costs when parties are left to their own procedural devices? Michael McIlwrath and I address these important topics and others in this contribution, with his perspective as a user of arbitration alongside mine as an arbitrator.
The Arbitrability of Administrative Contracts
Authors: El Mahdi Mohamed Amin 
Published: July 2022

An administrative contract is subject to a legal regime, the essence of which is the consensual nature of the contract combined with the proper functioning of public service. The absence of this feature from the consideration of arbitral tribunals, especially in investment disputes, was the basis of a theoretical gap from which a legal trend affirming a contrast between the nature of administrative contracts and the arbitration system emerged. A legitimate question arises as to whether the recent attention given by arbitration tribunals to this issue, especially in investment disputes, might allow scholars to overcome their differences regarding the arbitrability of administrative contracts.
técnica de las 3Rs y las actitudes ambientales en niños y niñas de una institución educativa – Huancavelica
Authors: Rojas Quinto Ana 
Published: July 2022

El objetivo de esta investigación fue determinar la influencia de la técnica de las 3Rs relacionadas a las actitudes ambientales de los niños y niñas de la Institución Educativa de educación primaria ubicada en una zona rural del distrito de Moya, Huancavelica. Métodos: investigación aplicada, con un diseño preexperimental, para el cuál se ha diseñado instrumentos para una prueba de actitud ambiental, hoja de aplicación y ficha de observación. La muestra poblacional fue de 22 alumnos, entre niños y niñas del primero al sexto grado, de la Institución Educativa N° 36053. Se aplicó la prueba de la actitud ambiental sobre la técnica de las 3Rs (3 erres); luego, se hizo la evaluación de las actitudes ambientales a través de una prueba de actitud ambiental y hoja de aplicación. Los resultados muestran en la prueba de entrada, el 77% (17) del total de la muestra de estudio, tienen una actitud negativa, y solo el 23% (5) tienen actitud positiva; es decir, al inicio de la investigación la actitud ambiental fue negativa; después de la aplicación de la técnica de las 3Rs, la situación se revierte, porque la mayoría (86%) de los niños y niñas obtuvieron una actitud ambiental positiva; en tanto que en el 14% (3) de los niños no demuestran cambio respecto a la actitud ambiental. Conclusión: la técnica de las 3Rs influye de manera muy significativa en las actitudes ambientales de los niños y niñas de dicha institución.
Biomateriais aplicados na substituição óssea em procedimentos odontológicos
Authors: Gonçalves Sulzer Bruno , Costa Borges Emilly Cristina , Arcangelo Silva Laís Fernanda 
Published: July 2022

A ausência de um órgão ou de um fragmento do corpo ocasiona, além da perda da função, transtornos sociais e psicológicos; os avanços obtidos na medicina e odontologia moderna, aliados ao aumento da expectativa de vida, têm possibilitado o andamento de técnicas que estabelecem uma melhor qualidade ao paciente. Este estudo teve como objetivo evidenciar o uso dos biomateriais na odontologia, destacando a origem, as propriedades e as reações biológica desses materiais no organismo humano. Trata-se de uma revisão descritiva de literatura, com buscas realizadas em bancos de dados científicos através das palavras chaves: defeito ósseo, biomateriais para defeitos ósseos, propriedades dos biomateriais, enxertos ósseos.
Caracterização clínico-epidemiológica de pacientes com lesão renal aguda dialítica em uma Unidade de Terapia Intensiva de um Hospital Universitário em Campo Grande, Mato Grosso do Sul
Authors: Sales Mayer Ana Carolina , Castilho Suguimoto Nicole Hitomi , Zanata Ribeiro Alves Gonçalves Patrícia de Fátima 
Published: July 2022

A lesão renal aguda (LRA) é uma síndrome clínica definida pelo declínio abrupto da taxa de filtração glomerular suficiente para reduzir a eliminação de produtos residuais nitrogenados e outras toxinas urêmicas. A incidência e prevalência entre pacientes internados em unidade de terapia intensiva (UTI) possui mortalidade variável. Realizou-se o presente estudo afim de avaliar a incidência, etiologia, características clínicas e desfechos dos pacientes que desenvolveram LRA dialítica na UTI em Hospital Universitário de Campo Grande/MS. Os dados foram obtidos através de análise de banco de dados secundários retrospectivos, entre 2018 e 2019. Constatou-se que a maioria significante dos pacientes haviam sido submetidos à hemodiálise devido a LRA KDIGO 3, eram predominantemente do sexo feminino e com idade menor ou igual a 65 anos, tendo sepse como principal etiologia da LRA. Além disso, houve aumento do tempo de internação e mortalidade, especialmente naqueles com idade mais avançada. Concluiu-se que os dados apresentados por este estudo são semelhantes aos dados apresentados pela literatura e devem encorajar os demais estudos no campo
Pengaruh Konsentrasi PM 10 Dengan Beberapa Keluhan Kesehatan Di PT Intimkara Ternate
Authors: Muliyadi Muliyadi , Sarjan Monalisa 
Published: July 2022

PT Intimkara kelurahan tubo merupakan pabrik pembuatan material yang berbahan dasar semen dan pasir. Penelitian ini bertujuan untuk mengetahui pengaruh PM 10 terhadap gangguan kesehatan. Desain penelitian ini adalah analisis dengan pendekatan cross sectional. Data diambil dengan pengukuran langsung dilapangan dan observasi selama 24 jam. Populasi subyek penelitian ini adalah seluruh pekerja (8) di PT Intimkara dan 8 masyarakat yang tidak terpapar debu di PT intimcara yang diambil secara random. sedangkan populasi objek adalah udara ambien di PT Intimkara. Sampel subyek yaitu 8 reponden grup control dan 8 responden grup kasus sedangkan sampel objek adalah 5 titik lokasi sampling. Pengumpulan data gangguan kesehatan dilakukan dengan wawancara sedangkan konsentrasi PM10 dilakukan dengan cara pengukuran. Pengukuran kelembaban dan suhu dilakukan dengan menggunakan hygrometer. Analisis data pengaruh dilakukan dengan menggunakan analisis regresi binary logistik. Konsentrasi PM10 selama 24 jam adalah 33µg/m3. Dari data analisis diketahui bahwa batuk berdahak terhadap nilai PM 10 memiliki nilai p sebesar 0.007 < 0.05, sementara nyeri dada terhadap nilai p sebesar 0.552>0,05 dan sesak napas terhadap nilai PM 10 memiliki nilai p sebesar 0.039<0.05. Disimpulkan bahwa PM 10 mempengaruhi kejadian, batuk berdahak dan sesak napas sementara PM 10 tidak mempengaruhi nyeri dada.
Effects of School Environment, Classroom Instruction, and Self-efficacy on Chinese Students’ Motivation for Oral English
Authors: Bizhu He  , Shiyu Guo  , Qian Chen  , Hector Rivera  
Published: July 2022

In this study, we examined the relationships among students’ self-efficacy of oral English competency, oral English environment in college, English class instruction, and motivation. The participants were 1,045 non-English-major freshman and sophomore students from a tier-one university in central China. Hypotheses were tested with a structural equation model (SEM), which controlled for gender, age, major, the score of English college entrance examination, and extra time spent on oral English learning. The overall model yielded a good fit with the data (CFI = .95, TLI = .94 RMSEA = .05, and χ2(230) = 796.50, p< .01). The results showed that students’ self-efficacy positively mediated the effects of college oral English learning environment in predicting students’ oral English motivate on. The significant positive effects of the environmental and instructional factors on motivation via self-efficacy suggest that students will benefit from school activities and instructional approaches that foster their expected English learning goals. Policy recommendations to motivate university students in English-foreign-language contexts are provided based on the findings.
Maternidade rima com Universidade?
Authors: Andrade Alves Christiane 
Published: July 2022

Não se apresse a responder, estimada(o) leitor(a). Convido-lhe a tomar um tempo. Ao tempo que compartilho nesta resenha algumas impressões e reflexões provocadas pelo documentário ‘Hora Incerta’; do pranto das mães que é invisível às estatísticas, para além dos outros tantos fatores de exclusão das mulheres dos bancos universitários. Do curso solitário, mas não só, também fragmentário, antes que tortuoso, por vezes impossível. O retrato registrado no mencionado documento audiovisual decerto não se restringe ao quadro discente de mães da Universidade Federal de São João del-Rei-MG ali concentrado, mas se expande pelo país alcançando tantas outras mulheres que encolhem. Por favor, leitor(a), sente-se e sinta.
Cheilosia (Diptera, Syrphidae: Rhingiini) of Nepal with descriptions of 29 new species
Authors: Barkalov Anatolij V. , Ståhls Gunilla 
Published: July 2022

The genus Cheilosia (Diptera: Syrphidae: Rhingiini) of Nepal is reviewed. We recorded 37 species of Cheilosia, of which 29 species are described here. Twenty-six of the new species are classified to a subgenus: Cheilosia (Cheilosia) angusta sp. nov., C. (C.) falcata sp. nov., C. (C.) hauseri sp. nov., C. (C.) maculata sp. nov., C. (C.) pica sp. nov., C. (C.) pilivena sp. nov., C. (C.) spinosa sp. nov., C. (C.) spuria sp. nov., C. (C.) weiperti sp. nov., C. (Montanocheila) albipicta sp. nov., C. (M.) alpha sp. nov., C. (M.) brevimontana sp. nov., C. (M.) gilva sp. nov., C. (M.) minuscula sp. nov., C. (M.) nigella sp. nov., C. (M.) pernigra sp. nov., C. (M.) picta sp. nov., C. (Floccocheila) collis sp. nov., C. (F.) crassata sp. nov., C. (F.) illustratoides sp. nov., C. (F.) indistincta sp. nov., C. (F.) leucozonoides sp. nov., C. (F.) vellea sp. nov., C. (Eucartosyrphus) procera sp. nov., C. (Pollinocheila) rava sp. nov., and C. (Taeniochilosia) nepalensis sp. nov. The remaining three new species, C. flavigena sp. nov., C. insolita sp. nov., and C. versa sp. nov., are described based on a female only, and are thus not classified to a subgenus. The subgenus Taeniochilosia Oldenberg, 1916 is here re-defined to also include species with a pilose eye in combination with the previously defined characters. Cheilosia nigriventris Barkalov & Cheng, 2004 is herewith placed as junior synonym of Cheilosia erratica Barkalov & Peck, 1997, and the description of the female sex is provided. We provide digital photographs and line drawings to illustrate morphological details of all species, and an identification key to the subgenera and to the species recorded for Nepal. We explored the infrageneric classification of some Nepalese species new to science for which molecular work was possible using mtDNA COI barcode sequences. A maximum likelihood analysis of the assembled COI barcode dataset with multiple representatives of the most speciose Palearctic subgenera of Cheilosia resolved the included seven taxa from Nepal within subgenera Cheilosia s. str. and Montanocheila Barkalov, 2002. The large number of new species of this study highlights the still prevailing incomplete knowledge of this speciose genus in the montane regions of the Palearctic and Oriental realms.
A Comparison of Staff Development Policies and Practices and Teachers’ Job Performance in Nigerian and Pakistani Universities
Authors: Adewale Awodiji Omotayo , Y. S. Ijaiya Nike , Ahmad Mansoor 
Published: July 2022

A university’s ability to remain competitive in a knowledge-driven world depends on the development of its teaching staff. The government and the private sector have invested in staff development in Nigerian and Pakistani universities. This article compares their staff development policies and practices as well as teachers’ job performance. An expo-facto comparative research design was adopted. We found significant differences between universities’ staff development policies and practices as well as lecturers’ job performance in the two countries (F (3, 657) = 41.879, ρ =.000). The article recommends effective implementation of staff development policies (funding, selection, performance appraisal, and promotion) to enhance staff’s skills and competencies and improve Nigerian universities’ position in global rankings.
Key words: Staff development, policies, practices, teachers, performance
Gender-Related Factors Influencing Female Students’ Participation in Higher Education in Rwanda
Authors: Rubagiza Jolly , Umutoni Jane , Iyakaremye Innocent 
Published: July 2022

Rwanda is widely seen as one of the most progressive countries in the world with regard to promoting gender equality and women’s empowerment. In education, for example, girls’ access to primary and secondary education is among the highest in Africa. However, female students’ participation remains limited in public universities and they constitute only around a third of the student population at the University of Rwanda. This article explores the factors that influence female students’ participation in public higher education in the country. It draws from a study commissioned by the University of Rwanda on the causes of low female enrolment at the institution that was conducted between 2016 and 2017. The study employed a mixed methods approach, and data was gathered by means of questionnaires, in-depth interviews, and focus group discussions. The results revealed interlinked structural (such as university policies) and socio-cultural factors that contribute to the exclusion of female students from Rwanda’s top university. Given the complexities involved, this calls for a multi-pronged approach to address the issue of female representation at the University.
Key words: Gender disparities, female students, higher education, Rwanda
A single-shot determination of differential gene network on multiple disease subtypes
Authors: Sadhu Arnab , Bhattacharyya Balaram , Mukhopadhyay Tathagato 
Published: July 2022

Differential gene expressional network determines the prominent genes under altered phenotypes. Traditional approach requires n(n-2)/2 comparisons for n phenotypes. We present a direct method for determining the differential network under multiple phenotypes.
We explore the non-discrete nature of gene expression as a pattern in fuzzy rough set. An edge between a pair of genes represents positive region of fuzzy similarity relation upon a phenotypic change. We apply a weight ranking formula and obtain a directed ranked network; we term it as Phenotype Interweaved Network. Nodes with large in-degree connectivity bubble up as significant genes under respective phenotypic changes.
We test the method on datasets of six diseases and achieve good corroboration with results of previous studies in two-step approach. The subgraphs of isolated genes achieve good significance upon validation through information theoretic approach. Top ranking genes determined in all our case studies have parity with genes reported by wet-lab tests.
A Diffusion Model of Binary Systems Controlled by Chemical Potential Gradient
Authors: Wróbel Marek , Burbelko Andriy 
Published: July 2022

The paper presents a model of diffusion in a single phase with chemical potential gradient as the driving force of the process. Fick’s laws are strictly empirical and the assumption that the concentration gradients are the driving forces of diffusion is far from precise. Instead, the gradient of chemical potential μi of component i is the real driving force. The matter of governing equations of models that incorporate this approach will be raised and discussed in this article. One of more important features is the ability to acquire results where diffusion against the concentration gradient may occur. The presented model uses the Finite Difference Method (FDM) and employs the CALPHAD method to obtain chemical potentials. The calculations of chemical potential are carried out for instant conditions – temperature and composition – in the entire task domain by Thermo-Calc via a TQ-Interface. Then the heterogeneity of chemical potentials is translated into mass transfer for each individual element. Calculations of two modelling tasks for one-dimension diffusion field were carried out. First: isothermal conditions with linear initial composition distribution and second: constant temperature gradient with uniform chemical composition in the specimen. Results for two binary solid solutions: Fe-C and Fe-Si, in the FCC phase for the given tasks will be presented. Modelling allows us to estimate the time needed to reach a desired state in a particular equilibrium or quasi-equilibrium state. It also shows the path of the composition change during the process. This can be used to determine whether the system at some point is getting close to the formation of another phase due to significant deviation from its initial conditions.