bluuebunny/crossref_metadata_2025_split huggingface dataset:
Karakteristik Fisik dan Aktivitas Antioksidan Sediaan Masker Gel Peel Off Ekstrak Metanol Daun Eceng Gondok
Authors: Ukhty Nabila , Khairi Ikhsanul , Dari Tika Wulan 
Published: March 2022

Gel peel off face mask is one type of facial mask that can increase the comfort of use and is expected to increase antioxidant activity on the skin. The mask is shaped like a paste, with a thick texture. Eceng gondok (Eichhornia crassipes) is an aquatic plant that lives wildly in the waters of West Aceh. The purpose of this study was to determine the yield of methanolic crude extract of eceng gondok’s leaves and to find out the best formulation of gel peel off face mask from methanol crude extract of eceng gondok’s leaf based on the physical characteristics of the mask. The extraction method used was maceration using methanol as a solvent. The differences in the composition of the extracts used were concentrations of 0%, 2%, 4% and 6%. Exploration of bioactive compounds in crude extract using phytochemical test. Assessment of the physical characteristics of the mask preparation included organoleptic tests, homogeneity, adhesion, dispersibility, pH, and drying time. The crude extract contains flavonoid compounds, tannins, steroids, terpenoids, and saponins. Formulation 3 for making gel peel off masks was the best mask with an assessment of its homogeneity being stable and no change, adhesion for 5.30 seconds, dispersion of 5.9 cm, pH 6.4, and drying in 27.48 minutes. The formula has DPPH inhibition (% inhibition) of 76.54%..
Site Amplifications from Earthquake Data and VS30 in the Fort Worth Basin, Texas
Authors: Jeong SeongJu , Stump Brian W. , DeShon Heather R. 
Published: March 2022

Abstract
Following the development of unconventional oil and gas production in the Fort Worth Basin, Texas, a rapid increase in basin-wide seismicity began in 2008 that grew to include earthquakes affecting a substantial portion of the Dallas–Fort Worth metropolitan area. To assess and mitigate the seismic hazard, which in this region is impacted by the thickness of the sedimentary basin and accompanying soft soil layer, we estimate site effects at 22 seismic stations deployed to record these earthquakes. Site responses are derived using two different datasets and approaches: (1) a modified generalized inversion technique (GIT) based on the S-wave Fourier amplitude spectra from earthquakes; and (2) application of the quarter-wavelength approximation (QWA) using estimates of average shear-wave velocities in the upper 30 m, known as VS30. We find that site amplification estimates based on the two techniques are roughly consistent with one another (median of the amplification ratio = 0.92) over frequencies where a quarter-wavelength corresponds to ∼30 m depth. The site amplification factors from the two approaches are found on average to be about 3 at the quarter-wavelength frequency (QWF). These site amplification estimates are not well correlated with geologic characteristics including rock type and geologic age. Finally, QWA values at six sites do not match GIT site amplification at the QWF (outside of ± median absolute deviations boundary), which we attribute to a combination of the underlying assumptions of the QWA, uncertainty in VS30 estimates, and unmodeled site response complexity.
Seismic Anisotropy Reveals Stress Changes around a Fault as It Is Activated by Hydraulic Fracturing
Authors: Igonin Nadine , Verdon James P. , Eaton David W. 
Published: March 2022

Abstract
Subsurface stress conditions evolve in response to earthquakes or fluid injection. Using observations of an induced seismicity sequence from a dense local array, anisotropy analysis is employed to characterize stress changes around a fault. The dataset comprises high signal-to-noise ratio S-wave data from 300 events, ranging in magnitude from −0.45 to 4.1, recorded on 98 three-component geophones cemented in shallow wells. It is found that the orientation of the fast S-wave direction remains relatively constant for all stations over time, but the magnitude of the anisotropy, as measured by the delay time between the fast and slow S wave, exhibits significant local variations. Some stations experience a systematic increase or decrease in the delay time, with a spatial coherence about the injection well. The stress changes due to hydraulic fracturing, aseismic slip, and observed earthquakes are modeled to determine the best fit to the observed anisotropy changes. Our analysis indicates that the creation of a network of tensile hydraulic fractures during fluid injection is likely to be the cause of the observed anisotropy changes. This study confirms that the measurements of seismic anisotropy over time reflects the evolving stress state of a fault prior to and during rupture.
Osteology of the cranium and Weberian apparatus of African catfish families (Teleostei: Ostariophysi: Siluriformes) with an assessment of Palaeogene genera
Authors: Murray Alison M , Holmes Robert 
Published: March 2022

Although the vast majority of fossil catfish material is isolated elements such as fin spines, a number of fossil catfishes (Siluriformes) have been named based on articulated crania from Palaeogene formations of Africa. The fossil taxa from marine sediments have been assigned to the extant marine family Ariidae, or have been assumed to have washed into marine sediments from freshwater habitats. The ability to assess the relationships of these fossils without reference to the nature of the geological sediments may provide insight into the history of these families. Most of the taxonomic work on the 11 catfish families found in Africa has focused on soft-tissues or DNA, which is problematic for the fossil material. Here we provide osteological features to distinguish families of African catfishes; eight of the families that are likely to be found in fossiliferous deposits can be distinguished based on a combination of skull features including the morphology of the cranial fontanelle, mesethmoid, and dermal ornamentation. We reassess the familial placement of the Palaeogene catfishes. We find that †Eomacrones wilsoni, from the Palaeocene of Nigeria, belongs in Bagridae s.s. This confirms that bagrids were in Africa much earlier than the Miocene. Because this catfish comes from Palaeocene marine sediments, the biogeographic history of Bagridae needs to be reassessed to consider marine dispersal in this taxon.
Análise de chuvas intensas para projetos de drenagem
Authors: Back Álvaro José , Cadorin Sabrina Baesso , Bonfante Fernanda Martins , Amaral Lucas Kister 
Published: March 2022

O conhecimento das relações IDF é de grande importância no dimensionamentos de obras de macro e microdrenagem. Para o planejamento das obras, além do conhecimento das relações IDF, também é importante conhecer as épocas do ano com maior risco de ocorrência de eventos extremos. Nesse sentido este trabalho teve como objetivo analisar a série histórica de chuva determinando as relações IDF e a ocorrência sazonal dos eventos extremos de chuva da estação pluviométrica de Vargem do Cedro, município de São Martinho. No estudo foram usados os dados diários de precipitação do período de 1977 a 2018 da estação pluviométrica de Vargem do Cedro (Código 02848006), localizada no Município de São Martinho, SC. Com base nas séries de máximas anuais de chuva com duração de 1 a 10 dias foram estimadas as chuvas máximas com período de retorno de2 a100 anos, usando a distribuição de Gumbel-Chow (BACK, 2013). Com base nas relações entre chuvas de diferentes durações (CETESB, 1986) foram estimadas as chuvas com duração de 5 a 1440 minutos, ajustando-se a equação IDF para chuvas de curta duração. Também foram avaliadas as frequências sazonais das ocorrências dos valores de chuvas diárias máximas anuais e de chuvas iguais ou superiores a 80 e 100 mm. A análise da série histórica de chuva permitiu estabelecer os valores de chuva máxima com duração de um a dez dias para serem usadas em projetos de macrodrenagem, bem como a equação IDF para chuvas de curta duração, a ser usada em projetos de microdrenagem. Foi constatada maior frequência de eventos extremos de duração diária nos meses de dezembro a fevereiro.
A importância das infraestruturas de transporte para o desenvolvimento industrial brasileiro: um enfoque Rangeliano para superação da crise atual
Authors: Rippel Nilmar , Viceli Alessandro , Dentz Eduardo Von 
Published: March 2022

Este trabalho tem por objetivo apontar a interpretação de Rangel, acerca da crise da dívida nos anos 1980 via concessão dos serviços de utilidade pública à iniciativa privada, ressaltando a importância simbiótica entre as infraestruturas de transporte e o setor industrial com vistas à superação da crise atual. O artigo demonstra, que é imprescindível considerar a importância do setor de transportes - no caso em particular os modais rodoviário e ferroviário - para o desenvolvimento econômico brasileiro. Pode-se dizer, que os principais resultados encontrados foram a potencialidade dos investimentos no setor, como sendo estratégicos para alavancagem industrial, o restabelecimento do emprego e consequentemente uma nova fase de crescimento, tendo em vista os efeitos multiplicativos em escala crescente e ampliada em todo o país. Ressalta-se também, a implementação Programa de Aceleração do Crescimento (PAC) a partir de 2007 e, a necessidade de continuidade dessas políticas econômicas para a superação da crise atual. Metodologicamente o artigo foi construído através da revisão bibliográfica, levantamento de dados e trabalhos de campo.
De novo assembly and analysis of the transcriptome of the Siberian wood frog Rana amurensis
Authors: Smirnov D. N. , Shekhovtsov S. V. , Shipova A. A. , Gazizova G. R. , Shagimardanova E. I. , Bulakhova N. A. , Meshcheryakova E. N. , Poluboyarova T. V. , Khrameeva E. E. , Peltek S. E. , Berman D. I. 
Published: March 2022

The Siberian wood frog Rana amurensis Boulenger, 1886 is the most hypoxia-tolerant amphibian. It can survive for several months in an almost complete absence of oxygen. Little is known about the mechanisms of this remarkable resilience, in part because studies of amphibian genomes are impeded by their large size. To make the Siberian wood frog more amenable for genetic analysis, we performed transcriptome sequencing and de novo assembly for the R. amurensis brain under hypoxia and normoxia, as well as for the normoxic heart. In order to build a de novo transcriptome assembly of R. amurensis, we utilized 125-bp paired-end reads obtained from the brain under normoxia and hypoxia conditions, and from the heart under normoxia. In the transcriptome assembled from about 100,000,000 reads, 81.5 % of transcripts were annotated as complete, 5.3 % as fragmented, and 13.2 % as missing. We detected 59,078 known transcripts that clustered into 22,251 genes; 11,482 of them were assigned to specific GO categories. Among them, we found 6696 genes involved in protein binding, 3531 genes involved in catalytic activity, and 576 genes associated with transporter activity. A search for genes encoding receptors of the most important neurotransmitters, which may participate in the response to hypoxia, resulted in a set of expressed receptors of dopamine, serotonin, GABA, glutamate, acetylcholine, and norepinephrine. Unexpectedly, no transcripts for histamine receptors were found. The data obtained in this study create a valuable resource for studying the mechanisms of hypoxia tolerance in the Siberian wood frog, as well as for amphibian studies in general.
Transcriptional activity of repair, apoptosis and cell cycle genes (TP53, MDM2, ATM, BAX, BCL-2, CDKN1A, OGG1, XPC, PADI4, MAPK8, NF-KB1, STAT3, GATA3) in chronically exposed persons with different intensity of apoptosis of peripheral blood lymphocytes
Authors: Nikiforov V. S. , Blinova E. A. , Kotikova A. I. , Akleyev A. V. 
Published: March 2022

Transcriptional activity of genes involved in maintaining genetic homeostasis (genes for repair, cell cycle and apoptosis: TP53, MDM2, ATM, BAX, BCL-2, CDKN1A, OGG1, XPC, PADI4, MAPK8, NF-KB1, STAT3, GATA3) was studied in chronically exposed persons with an increased intensity of early and late stages of apoptosis and necrosis of peripheral blood lymphocytes. The object of this study was peripheral blood mononuclear cells obtained from 132 chronically exposed residents of the Techa riverside villages. The mean accumulated dose to red bone marrow was 426.4±48.2 mGy (1.3–2930.0 mGy), to thymus and peripheral immune organs, 58.9±7.9 mGy (0.1–489.0 mGy). The study was performed more than 60 years after the onset of exposure, the average age of exposed persons was 68±0.6 years (55–86 years). The study of apoptotic and necrotic death of peripheral blood lymphocytes was based on the presence of phosphatidylserine on the cell membrane surface, as well as on its permeability for DNA-intercalating dye. Evaluation of the relative content of mRNA genes for repair, cell cycle, and apoptosis was carried out using real-time PCR. An increased relative content of PADI4 gene mRNA was registered in the group of chronically exposed persons with the increased intensity of early apoptosis (p = 0.006). Modulation of the relative content of mRNA of the TP53 (p = 0.013) and BCL-2 (p = 0.021) genes was detected in the group of chronically exposed individuals with the increased intensity of the late stage of apoptosis. A statistically significant increase in the transcriptional activity of the TP53 gene was observed in the group of chronically exposed persons with the increased intensity of peripheral blood lymphocyte necrosis in the long-term period (p = 0.015). In the course of the study it was noted that exposed people with increased intensity of apoptosis, first of all, demonstrate changes in the transcriptional activity of apoptotic genes. These data are consistent with current views on the activation of programmed cell death.
Can measurement of glucose levels in blood and peritoneal fluid be used to diagnose septic peritonitis in dogs?
Authors: D'Mello Nicole 
Published: March 2022

PICO question
Can the measurement of blood and peritoneal fluid effusion glucose levels be used to accurately diagnose septic peritonitis in dogs when compared to cytology and bacterial culture?

Clinical bottom line
Category of research question
Diagnosis
The number and type of study designs reviewed
Three papers were critically reviewed, all of which were diagnostic test evaluation studies
Strength of evidence
Moderate
Outcomes reported
Glucose measurements can be used to diagnose septic peritonitis when the blood plasma glucose level is >2.1 mmol/L higher than that of the peritoneal fluid glucose when using a veterinary point of care (POC) glucometer. If using a biochemistry analyser, a whole blood glucose >1.1 mmol/L higher than that of the peritoneal fluid can be used to diagnose septic peritonitis. This is only relevant when the peritoneal fluid is collected by abdominocentesis and not in a postoperative period
Conclusion
At present, there is moderate evidence that glucose measurements are useful as a patient side test for the diagnosis of septic peritonitis and are especially useful in cases where intracellular bacteria cannot be identified on cytology. However, despite the so far promising accuracy results, the cut-offs reported are quite variable and overall, there is not a single diagnostic test that is 100% sensitive and specific in repeated studies. Therefore, the results of the glucose measurements should be evaluated alongside other biomarker testing, imaging modalities and the clinical presentation of the patient. Glucose measurements cannot currently replace culture / sensitivity and cytology as the gold standard for the diagnosis of septic peritonitis

How to apply this evidence in practice
The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.
Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.
Treatment of Subchondral Bone Marrow Edema with Intralesional Viscous Bone Cement in a Young, Active Patient
Authors: Vander Molen Jonathan , Berlinberg Elyse J. , Forsythe Brian 
Published: March 2022

Case:
A 23-year-old male patient presented with symptomatic, high-grade medial tibial plateau bone marrow edema unresponsive to conservative treatment. After the injection of intralesional viscous bone cement, the patient had resolution of his symptoms and returned to running.

Conclusion:
The use of intralesional viscous bone cement has grown in popularity for the treatment of bone marrow edema in individuals older than 40 years but is uncommon in younger individuals. This case demonstrates that intralesional viscous bone cement may be considered in the treatment of high-grade bone marrow edema in young, active patients who are unresponsive to extensive conservative management.
Spontaneous Renal Hemorrhage: Case Report and Review of the Literature
Authors: Paudel Subhash , Steinberg Peter , Denker Bradley 
Published: March 2022

Abstract
Introduction:Spontaneous renal hemorrhage (SRH) is an uncommon condition which is usually associated with renal neoplasms or vasculitis. Management of SRH is uniquely challenging in cases of solitary functioning kidney as the risks and benefits of surgical intervention and conservative management need to be carefully considered. Case Presentation:We report a case of a 67-year-old woman with recurrent bilateral nephrolithiasis with an atrophic right kidney who presented with left flank pain and acute kidney injury similar to prior episodes of nephrolithiasis. She was found to have SRH in her solitary functioning kidney and was managed non operatively. Conclusion:Clinical presentation of SRH can be similar to that of nephrolithiasis or pyelonephritis and a high index of suspicion is required to diagnose this life-threatening condition. Management of SRH is especially challenging in patients with solitary kidney. As this case illustrates, management decisions should be individualized and conservative care with close monitoring is an option in selective situations.
Self-care interventions for sexual and reproductive health in humanitarian and fragile settings: a scoping review
Authors: Dawson Angela , Tappis Hannah , Tran Nguyen Toan 
Published: March 2022

Abstract
BackgroundSelf-care is the ability of individuals, families, and communities to promote health, prevent disease, maintain health, and manage illness and disability with or without a health care provider. In resource-constrained settings with disrupted sexual and reproductive health (SRH) service coverage and access, SRH self-care could play a critical role. Despite SRH conditions being among the leading causes of mortality and morbidity among women of reproductive age in humanitarian and fragile settings there are currently no reviews of self-care interventions in these contexts to guide policy and practice.MethodsWe undertook a scoping review to identify the design, implementation, and outcomes of self-care interventions for SRH in humanitarian and fragile settings. We defined settings of interest as locations with appeals for international humanitarian assistance or identified as fragile and conflict-affected situations by the World Bank. SRH self-care interventions were described according to those aligned with the Minimum Initial Services Package for Reproductive Health in Crises. We searched six databases for records using keywords guided by the PRISMA statement. The findings of each included paper were analysed using an a priori framework to identify information concerning effectiveness, acceptability and feasibility of the self-care intervention, places where self-care interventions were accessed and factors relating to the environment that enabled the delivery and uptake of the interventions.FindingsWe identified 25 publications on SRH self-care implemented in humanitarian and fragile settings including ten publications on maternal and newborn health, nine on HIV/STI interventions, two on contraception, two on safe abortion care, one on gender-based violence, and one on health service provider perspectives on multiple interventions. Overall, the findings show that well-supported self-care interventions have the potential to increase access to quality SRH for crisis-affected communities. However, descriptions of interventions, study settings, and factors impacting implementation offer limited insight into how practical considerations for SRH self-care interventions differ in stable, fragile, and crisis-affected settings.Conclusion It is time to invest in self-care implementation research in humanitarian settings to inform policies and practices that are adapted to the needs of crisis-affected communities and tailored to the specific health system challenges encountered in such contexts.
Band Decomposition of Asynchronous Electroencephalogram Signal for Upper Limb Movement Classification
Authors: Kulkarni Vinay Vasantrao , Joshi Yashwant V. , Manthalkar Ramachandra R. , Elamvazuthi Irraivan 
Published: March 2022

Abstract
Decoding Asynchronous Electroencephalogram (A-EEG) signals is a crucial challenge in the emerging field of EEG based Brain-Computer Interface (BCI). In the case of A-EEG signals, the time markers of motor activity are absent. The paper proposes a method to decompose the A-EEG signals using Gabor Elementary Function (GEF) designed with Gabor frames. The scale-space analysis extracts Gabor dominant frequencies from A-EEG signals. Statistical and temporal moment dependent features are used to create the feature vector for each estimated Gabor Band (GB). The statistical significance of the features is tested with the Kruskal-Wallis test. The deep neural network is implemented with Bi-directional Long Short-Term Memory (BiLSTM) block to classify the upper limb movement. The EEG data of healthy volunteers have been collected using the Enobio-20 electrode system and ArmeoSpring rehabilitation device. The proposed methodology has achieved an average classification accuracy of 96.83%, precision 0.96, recall 0.96, and F1-score of 0.93 on the acquired data set. The designed framework for decoding upper limb movement outperforms the existing state-of-the-art methods. In the future, the proposed framework could increase classification performance by incorporating multiple types of biological inputs for investigating various brain functions.
Analysis of the Ophthalmic YAG-Laser Pulses Inside the Animal Eyes Using an Sscilloscope
Authors: Bantsykina Iuliia Vladimirovna , Malov Igor Vladimirovich , Grishanov Vladimir Nicolaevich , Nefedova Irina Feliksovna 
Published: March 2022

Abstract
Purpose
to study laser irradiation inside the eye.
Methods
we performed simulation and analysis of the physical effects of YAG laser during laser capsulotomy on the enucleated eyes of mature chinchilla rabbits by pulses fixation with photodetectors and evaluation of them on an oscilloscope.
Results
our study shows that the effect of the laser pulse on the eye membranes can be measured with a high-speed photodetector, that the results are stable and reproducible, the obtained pulses have the same configuration at all recording points.
Conclusion
the pulse amplitudes behind the posterior capsule of the lens and at the retina, when the pulse is applied to the posterior capsule, have no statistical difference, this can be explained by diffuse scattering of laser radiation inside the eye by the inner surface of the eye. Using our experimental model, it is possible to calculate the peak of the pulse reaching the retina and use this data in further experiments and clinical practice.