bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrating Lean Six Sigma with blockchain technology for quality management – a scoping review of current trends and future prospects
Authors: Ahmad Raja Wasim , Al Khader Walaa , Jayaraman Raja , Salah Khaled , Antony Jiju , Swarnakar Vikas 
Published: August 2022

PurposeThe purpose of this research is to study and analyze the literature that integrates Lean Six Sigma (LSS) approach with blockchain technology in different sectors for improved quality management.Design/methodology/approachThis study presents a scoping review on the application of integrated LSS and blockchain technology in the manufacturing and healthcare sector. Further, the authors examined existing blockchain-based solutions on a variety of dimensions, including application area, technical approach, methodology, application scenario, various blockchain platforms, purpose, and monitoring parameters. The authors study LSS approaches in detail, as well as the key benefits that blockchain technology can enable. Finally, the authors discuss significant research problems to be addressed in order to develop a highly efficient, resilient, and secure quality management framework using blockchain technology.FindingsIt has been observed that the adoption of blockchain technology for quality management and assurance is influenced by several factors such as transaction execution speed, throughput, latency. Also, prior blockchain-based solutions have neglected to leverage the benefits of LSS methodologies for effective quality management.Originality/valueThis is the first study to explores the influence of blockchain technology on quality management and assurance in manufacturing and healthcare industry. Furthermore, prior research has not examined how integrating the LSS methodology with blockchain technology can aid in the control of product quality management.
A comparative analysis of the environmental and social policies of the AIIB and World Bank
Authors: Apolinário Júnior Laerte , Jukemura Felipe 
Published: August 2022

AbstractThis paper presents a comparative analysis of the environmental and social policies of the Asian Infrastructure Investment Bank (AIIB) and the World Bank. Our objective is to assess how the AIIB innovates in the international financial order in terms of Environmental and Social Assessment (ESA) instruments. We analyse projects financed by the two institutions in India between 2017 and 2020, considering both institutions' social and environmental standards. First, we compare the social and environmental guidelines of both financial institutions extensively. Then, we analyse 20 projects carried out in India during this period, considering the amounts invested, risk classification policies, and the adopted ESA instruments. Finally, we conduct two case studies analysing each organization's ESA instruments based on 10 parameters of comparison. We conclude that the AIIB portrays itself as a ‘middle way’ bank, with the internalization of some standards of the already established multilateral development banks (MDBs), but with several innovative characteristics. We identify the incorporation of some World Bank guidelines used in ESA instruments in AIIB projects. Nevertheless, the AIIB innovates through its focus on infrastructure, the variability of its project sizes, more integration with the borrower's national policies and programmes, and the simplification of socio‐environmental analysis instruments.
The prevalence of fetal alcohol spectrum disorders in rural communities in South Africa: A third regional sample of child characteristics and maternal risk factors
Authors: May Philip A. , de Vries Marlene M. , Marais Anna‐Susan , Kalberg Wendy O. , Buckley David , Hasken Julie M. , Abdul‐Rahman Omar , Robinson Luther K. , Manning Melanie A. , Seedat Soraya , Parry Charles D. H. , Hoyme H. Eugene 
Published: August 2022

AbstractBackgroundThis study is the ninth cross‐sectional community study of fetal alcohol spectrum disorders (FASD) conducted by the multidisciplinary Fetal Alcohol Syndrome Epidemiology Research team in the Western Cape Province of South Africa. It is the third comprehensive study of FASD in a rural, agricultural region of South Africa.MethodsPopulation‐based, active case ascertainment methods were employed among a school‐based cohort to assess child physical and neurobehavioral traits, and maternal risk factor interviews were conducted to identify all children with FASD to determine its prevalence.ResultsConsent was obtained for 76.7% of 1158 children attending first grade in the region's public schools. Case–control results are presented for 95 with fetal alcohol syndrome (FAS), 64 with partial fetal alcohol syndrome (PFAS), 77 with alcohol‐related neurodevelopmental disorder (ARND), 2 with alcohol‐related birth defects (ARBD), and 213 randomly‐selected controls. Four techniques estimating FASD prevalence from in‐person examinations and testing yielded a range of total FASD prevalence of 206–366 per 1000. The final weighted, estimated prevalence of FAS was 104.5 per 1000, PFAS was 77.7 per 1000, ARND was 125.2 per 1000, and total FASD prevalence was 310 per 1000 (95% CI = 283.4–336.7). Expressed as a percentage, 31% had FASD. Although the rate of total FASD remained steady over 9 years, the proportion of children within the FASD group has changed significantly: FAS trended down and ARND trended up. A detailed evaluation is presented of the specific child physical and neurobehavioral traits integral to assessing the full continuum of FASD. The diagnosis of a child with FASD was significantly associated with maternal proximal risk factors such as: co‐morbid prenatal use of alcohol and tobacco (OR = 19.1); maternal drinking of two (OR = 5.9), three (OR = 5.9), four (OR = 38.3), or more alcoholic drinks per drinking day; and drinking in the first trimester (OR = 8.4), first and second trimesters (OR = 17.7), or throughout pregnancy (OR = 18.6). Distal maternal risk factors included the following: slight or small physical status (height, weight, and head circumference), lower BMI, less formal education, late recognition of pregnancy, and higher gravidity, parity, and older age during the index pregnancy.ConclusionThe prevalence of FASD remained a significant problem in this region, but the severity of physical traits and anomalies within the continuum of FASD is trending downwards.
Effects of psychological pressure on first‐mover advantage in competitive environments: Evidence from penalty shootouts
Authors: Santos Ricardo Manuel 
Published: August 2022

AbstractIn this paper, we aim to determine the importance of psychological pressure on performance in sequential tournaments. We make use of penalty shootouts in soccer and test the presence of first‐mover advantage. Shootouts in soccer is a formidable framework because it is a natural experiment where teams compete in a sequence whose order is determined by the random outcome of a coin toss. Using data from all 663 penalty shootouts in all major competitions since first implemented in 1970, we fail to identify statistically significant differences in winning probabilities for teams kicking first or second in the shootout sequence.
Spatial Alignment Facilitates Visual Comparison in Children
Authors: Zheng Yinyuan , Matlen Bryan , Gentner Dedre 
Published: August 2022

AbstractVisual comparison is a key process in everyday learning and reasoning. Recent research has discovered the spatial alignment principle, based on the broader framework of structure‐mapping theory in comparison. According to the spatial alignment principle, visual comparison is more efficient when the figures being compared are arranged in direct placement—that is, juxtaposed with parallel structural axes. In this placement, (1) the intended relational correspondences are readily apparent, and (2) the influence of potential competing correspondences is minimized. There is evidence for the spatial alignment principle in adults’ visual comparison (Matlen et al., 2020). Here, we test whether it holds for children. Six‐ and eight‐year‐old children performed a same‐different task over visual pairs. The results indicated that direct placement led to faster and more accurate comparison, both for concrete same‐different matches (matches of both objects and relations) and for purely relational matches—evidence that the same structural alignment process holds for visual comparison in 6‐ and 8‐year‐olds as in adults. These findings have implications for learning and education.
Two Cultural Processing Asymmetries Drive Spatial Attention
Authors: Mendonça Rita , Garrido Margarida V. , Semin Gün R. 
Published: August 2022

AbstractCultural routines, such as reading and writing direction (script direction), channel attention orientation. Depending on one's native language habit, attention is biased from left‐to‐right (LR) or from right‐to‐left (RL). Here, we further document this bias, as it interacts with the spatial directionality that grounds time concepts. We used a spatial cueing task to test whether script direction and the grounding of time in Portuguese (LR, Exp. 1) and Arabic (RL, Exp. 2) shape visuomotor performance in target discrimination. Temporal words (e.g., tomorrow, yesterday) were presented as cues in two modalities: visual (Exp. 1–2) and auditory (Exp. 1). Gaze movement (Exp. 1) and speed of discrimination decisions (Exp. 1–2) of targets presented to the left or right sides of the screen were assessed. As predicted, the interaction between target location and time concepts was significant across both modalities and linguistic communities. Additionally, LR participants detected the target on the right side of the screen faster after a future word than the target on the left side of the screen after a past word cue. In contrast, RL participants detected the target on the left side of the screen faster when the cue word was a future word than the target on the right side of the screen cued by a past word. In both modalities, the initial eye‐gaze movement (Exp. 1) was responsive to the cue's time referent, further confirming that time orients attention. An additional bias was observed for the first fixation onset, which landed earlier on the target set that matched habitualized spatial routines. We conclude that scanning regularities are shaped by writing habits and bodily grounded categorical features.
Dermatologische Lehre für Medizinstudierende: ein Scoping Review publizierter Interventionsstudien
Authors: Bernges Felix , Zielbauer Sebastian , Weberschock Tobias , Ochsendorf Falk 
Published: August 2022

ZusammenfassungEs ist unklar, wie Medizinstudierenden Dermatologie optimal vermittelt werden sollte. Daher wurde der vorliegende Scoping Review mit folgender Fragestellung durchgeführt: „Welche dermatologischen Lehransätze für Medizinstudierende wurden in publizierten Interventionsstudien untersucht?“. Ziele waren die Identifikation und strukturierte Darstellung aller relevanten Studien. Die Methodik dieses Scoping Reviews folgte der PRISMA Extension for Scoping Reviews. Die Datenbanken Medline und Embase wurden ohne Einschränkungen bis zum 30.06.2020 durchsucht. Eingeschlossen wurden veröffentlichte Interventionsstudien, die dermatologische Lehransätze mit Medizinstudierenden untersuchten. Es erfolgten eine Kategorisierung sowie eine deskriptive Analyse der als vollständige Artikel publizierten Studien. Die Datenbanksuche ergab 36 627 Treffer. 114 Studien erfüllten alle Einschlusskriterien. Diese stammten aus 19 Ländern, wurden überwiegend seit 2010 publiziert und verteilten sich auf 64 verschiedene Journale. 32 randomisierte kontrollierte Studien wurden identifiziert. Es fanden sich verschiedenste Lehransätze, welche sowohl E‐Learning als auch konventionelle Lehrformate umfassten. Die Resultate der Studien sind in strukturierten Tabellen aufgeführt. Dieser Scoping Review belegt eine hohe Zahl an weltweit publizierten Studien zur dermatologischen Lehre für Medizinstudierende. Die Vermittlung dermatologischer Inhalte scheint mit zahlreichen Lehransätzen zu gelingen, wobei Interventionen mit Berücksichtigung didaktischer Prinzipien nachweisbar erfolgreicher waren. Diese Literaturübersicht kann Lehrenden als Hilfestellung für eine evidenzbasierte Unterrichtsgestaltung dienen sowie eine Grundlage für künftige Forschungsansätze schaffen.
Very low carbohydrate (ketogenic) diets in type 2 diabetes: A systematic review and meta‐analysis of randomized controlled trials
Authors: Parry‐Strong Amber , Wright‐McNaughton Morag , Weatherall Mark , Hall Rosemary M. , Coppell Kirsten J. , Barthow Christine , Krebs Jeremy D. 
Published: August 2022

AbstractAimVery low carbohydrate/ketogenic diets (VLC/KDs) are popular but their role in managing pre‐diabetes and type 2 diabetes (T2D) is uncertain. This study uses a systematic review and meta‐analysis of randomized controlled trials to estimate the effect of these diets in this population.Materials and MethodsA systematic review identified randomized controlled trials of at least 6 months duration comparing efficacy and safety of VLC/KDs (≤50 g carbohydrate or ≤10% total energy from carbohydrate per day) with a control diet (carbohydrate above the VLC/KD threshold) in adults with pre‐diabetes or T2D. The primary outcome variable was glycated haemoglobin (HbA1c) after 12 months. The meta‐analysis method was inverse variance weighting of mean values for continuous variables.ResultsKey word searches identified 2290 studies; 2221 were not in scope. A full text review of 69 studies identified eight meeting inclusion criteria; in total, it involved 606 participants. Six studies reported HbA1c (%) at 12 months; four as change from baseline with a fixed effects estimate (95% confidence interval): VLC/KD minus control of 0.01% (−0.22 to 0.25), p = .91; and two as change from baseline: −0.65% (−0.99; −0.31) [−7.1 mmol/mol (−10.8; −3.4)], p < .001. Serum triglycerides were lower with VLC/KD versus control: −0.28 mmol/L (−0.44 to −0.11), p < .001. High‐density lipoprotein was higher with an estimate of 0.04 mmol/L (0.01 to 0.08), p = .03, in the five studies reporting 12‐month summary data.ConclusionsA VLC/KD may cause reductions in HbA1c and triglycerides in those with pre‐diabetes or T2D but evidence of an advantage over other strategies is limited. More well‐designed studies are required to provide certain evidence.
European Neuromuscular Centre consensus statement on anaesthesia in patients with neuromuscular disorders
Authors: van den Bersselaar Luuk R. , Heytens Luc , Silva Helga C. A. , Reimann Jens , Tasca Giorgio , Díaz‐Cambronero Óscar , Løkken Nicoline , Hellblom Anna , Hopkins Philip M. , Rueffert Henrik , Bastian Börge , Vilchez Juan Jesus , Gillies Robyn , Johannsen Stephan , Veyckemans Francis , Muenster Tino , Klein Andrea , Litman Ron , Jungbluth Heinz , Riazi Sheila , Voermans Nicol C. , Snoeck Marc M. J. 
Published: August 2022

AbstractBackground and purposePatients with neuromuscular conditions are at increased risk of suffering perioperative complications related to anaesthesia. There is currently little specific anaesthetic guidance concerning these patients. Here, we present the European Neuromuscular Centre (ENMC) consensus statement on anaesthesia in patients with neuromuscular disorders as formulated during the 259th ENMC Workshop on Anaesthesia in Neuromuscular Disorders.MethodsInternational experts in the field of (paediatric) anaesthesia, neurology, and genetics were invited to participate in the ENMC workshop. A literature search was conducted in PubMed and Embase, the main findings of which were disseminated to the participants and presented during the workshop. Depending on specific expertise, participants presented the existing evidence and their expert opinion concerning anaesthetic management in six specific groups of myopathies and neuromuscular junction disorders. The consensus statement was prepared according to the AGREE II (Appraisal of Guidelines for Research & Evaluation) reporting checklist. The level of evidence has been adapted according to the SIGN (Scottish Intercollegiate Guidelines Network) grading system. The final consensus statement was subjected to a modified Delphi process.ResultsA set of general recommendations valid for the anaesthetic management of patients with neuromuscular disorders in general have been formulated. Specific recommendations were formulated for (i) neuromuscular junction disorders, (ii) muscle channelopathies (nondystrophic myotonia and periodic paralysis), (iii) myotonic dystrophy (types 1 and 2), (iv) muscular dystrophies, (v) congenital myopathies and congenital dystrophies, and (vi) mitochondrial and metabolic myopathies.ConclusionsThis ENMC consensus statement summarizes the most important considerations for planning and performing anaesthesia in patients with neuromuscular disorders.
An unexpected route of temporary pacing lead
Authors: Soysal Ali Ugur , Durmaz Sebnem , Onel Muhammed , Yalin Kivanc 
Published: August 2022

AbstractCongenital anomalies of the venous system including superior (SVC) and inferior vena cava are not uncommon. Failure of certain vessels embryogenesis results in numerous caval variations and anomalies. Anomalies of systemic venous circulation are frequently seen in patients with congenital heart disease and are sometimes incidentally recognized. However, these are usually without significant clinical implications, detection of these anomalies is necessary to avoid diagnostic pitfalls and for planning vascular interventions. We present a rare caval anomaly, a left‐sided IVC with hemiazygos continuation to left SVC and coronary sinus.
Scarcity of major resistance genes against Verticillium wilt caused by Verticillium dahliae
Authors: Vermeulen Jasper P. , Hanika Katharina , Thomma Bart P. H. J. , Bai Yuling , Schouten Henk J. 
Published: August 2022

AbstractVerticillium dahliae is a soil‐borne fungal pathogen that causes vascular wilt disease in numerous plant species. The only described qualitative resistances against V. dahliae are the Ve1 gene and the V2 locus in tomato. These resistances have been overcome by virulent strains. We tried to identify additional resistances. Out of the methods we tested, comparing the canopy area of V. dahliae‐inoculated plants with mock‐inoculated plants yielded the best discriminative power in resistance tests. Out of six wild tomato accessions that were previously reported to possess some resistance, Solanum pimpinellifolium G1.1596 and Solanum cheesmanii G1.1615 displayed the lowest stunting and the least colonization by V. dahliae. Recombinant inbred line (RIL) populations were developed of both populations. No QTLs were identified in the G1.1596 RIL population. In the G1.1615 population, four small‐effect QTLs were associated with reduced stunting. Many studies in other hosts also failed to discover major resistance genes against V. dahliae. We hypothesize that the scarcity of major resistance genes against V. dahliae is caused by its endophytic behaviour in nature. The limited damage in nature would not lead to evolutionary pressure to evolve major resistances. However, in agriculture, V. dahliae can behave more pathogenic, leading to serious damage.
Management of acne in transgender and gender diverse youth Part 2: Unique considerations and strategies in medical treatment
Authors: Hollingshead Nicole , Hodax Juanita K. , Boos Markus D. 
Published: August 2022

AbstractAcne vulgaris is among the most common skin disorders afflicting adolescents worldwide, and though well‐established guidelines of care exist for acne management, these guidelines do not uniformly consider or address the unique psychosocial and medical needs of transgender and gender diverse (TGD) youth. Part 2 of this two‐part review provides guidance on a stepwise approach to the medical treatment of acne in TGD youth, with an emphasis on safety, efficacy, and the delivery of medical care in a culturally humble, thoughtful, and gender‐affirming manner.
The effects of free primary education in the Democratic Republic of Congo: A difference‐in‐differences approach
Authors: Kodila‐Tedika Oasis , Otchia Christian S. 
Published: August 2022

AbstractFollowing the Millennium Development Goals and the Dakar Framework for Action, many African countries instituted free primary education policies in 2000 to achieve universal primary education by 2015. However, the impact of free education policies remains understudied, particularly for late‐adopters. This paper estimates the short‐term effects of free primary education on enrollment in the Democratic Republic of Congo, where the policy was implemented as a trial in only two provinces in 2010. We exploit the spatial variations in adopting the policies using difference‐in‐differences with propensity score matching and show that free primary education policies significantly increase enrollment. We find large heterogeneity in the effects depending on the school management types. Catholic conventional school accounts for most of the enrollment due to the perceived quality, level of teacher knowledge, school infrastructure, and better service delivery.
Chikungunya in Brazil: An epidemic of high cost for private healthcare, 2017
Authors: de Margarette Oliveira de Andrade Maria , de Almeida Barreto Francisca Kalline , Coelho Tania Maria Silva , Praça Pinto Geovana , Queiroz Isabella Timbo , Nogueira Camila Távora , Freitas Andre Ricardo Ribas , Ferreira Marcelo Jose Monteiro , Alencar Carlos Henrique , de Góes Cavalcanti Luciano Pamplona 
Published: August 2022

AbstractObjectiveWe evaluated the impact of direct and indirect medical costs incurred through chikungunya infections in patients treated in Fortaleza, Brazil.MethodsCross‐sectional study about the cost of illness. The valuation method of medical costs was based on the micro‐costing approach (bottom‐up). The study was carried out in a large general hospital of the private health network. The study population consisted of patients treated as suspected cases of chikungunya and hospital professionals who applied for sick leave due to chikungunya.ResultsIn 2017, there were 2683 patients treated at this hospital who incurred an estimated cost of $383,514.40. From this amount, $174,322.91 (45.5%) were expended on emergency care, $194,700.59 (50.8%) on hospitalisations. 123 hospital professionals were infected with chikungunya and sick leave duration ranged between 1 and 19 days. Health professionals generated 746 days of absence and an amount of $14,490.90 due to absenteeism from work related to chikungunya. 31 symptoms were reported, especially arthralgia (91.1%) and fever (79.4%). There was a predominance of females (58.8%) and the age group of 20–39 years (42.1%).ConclusionThe average cost of admissions was over $2400. Considering the epidemic potential of chikungunya, our data indicate the huge economic burden of this disease to healthcare units in the presence of epidemics. Economic factors, added to the loss of life and the consequences of chronic chikungunya, make this disease a real scourge for countries with fewer material resources.