bluuebunny/crossref_metadata_2025_split huggingface dataset:
Invasive species control with apex predators: increasing presence of wolves is associated with reduced occurrence of the alien raccoon dog
Authors: Selonen V. , Brommer J. E. , Holopainen S. , Kauhala K. , Krüger H. , Poutanen J. , Väänänen V.-M. , Laaksonen T. 
Published: July 2022

AbstractThe role of an alien predator in the community depends on its interaction with native predators. The absence of apex predators may facilitate outbreaks of invasive mesopredators, but the effect of apex predators may vary between species and environments. We analysed the occurrence of a common invasive mesopredator in Europe, the raccoon dog (Nyctereutes procyonoides), and native mesopredators, the red fox and the Eurasian badger, in camera-trap data from Finland. The observations in cameras were analysed in relation to the presence of apex predators in the landscape (grey wolf and Eurasian lynx), human density, and habitat. We observed negative effect of increasing presence of wolves and lynxes on the occurrence of raccoon dogs. This effect appeared clear compared to the effects of habitat and human density. The effect of lynxes on raccoon dogs was clearer in areas with short growth season. For the occurrence of badgers, the presence of wolves had a weak negative effect and the presence of lynxes had a positive effect. For the occurrence of red foxes, wolves had a positive effect when agricultural fields were sparse in the landscape and lynxes had no effect. We also observed that the invasive raccoon dog currently appears to be the most common mesopredator within the study area. We conclude that the effect of apex predators on mesopredators depends on the environment and, in our case, was more suppressive on the alien mesopredator than on the native mesopredators. Thus, apex predators can play an important role in controlling invasive mesopredators.
Coping with uncertainty in everyday situations (CUES©) to address intolerance of uncertainty in autistic children: an intervention feasibility trial
Authors: Rodgers Jacqui , Goodwin Jane , Garland Deborah , Grahame Victoria , Isard Lucy , Kernohan Ashleigh , Labus Marie , Osborne Mr Malcolm , Parr Jeremy R , Rob Priyanka , Wright Catharine , Freeston Mark 
Published: July 2022

Abstract
Background
Anxiety related to uncertainty is common in autism. Coping with Uncertainty in Everyday Situations (CUES©) is a parent-mediated group intervention aiming to increase autistic children’s tolerance to uncertain situations. A pilot study was conducted to test its feasibility and acceptability.

Methods
Parents of 50 autistic children were randomised to receive CUES© or enhanced services as usual.

Results
All children met the clinical threshold for at least one anxiety disorder. Of the 26 participants randomised to CUES©, 72% attended 4–8 sessions. Parents and therapists reported they found CUES© useful and acceptable.

Conclusions
Families were willing to be recruited and randomised, the format/content was feasible to deliver, and the outcome measures were acceptable. CUES© should be evaluated in a clinical and cost effectiveness randomised controlled trial.
Enhancing carotenogenesis in terrestrial microalgae by UV-A light stress
Authors: Mutschlechner Mira , Walter Andreas , Colleselli Lucia , Griesbeck Christoph , Schöbel Harald 
Published: July 2022

AbstractCarotenoids are among the most widely distributed pigments in nature with broad application options in pharmacology, cosmetics and food industries. For commercial-scale production using microalgae, however, it is crucial to find the best performing strains regarding growth and yields of the products of interest. As terrestrial microalgae present the ability to quickly adapt to changing or unfavorable environmental conditions through cell-specific defense mechanisms, they constitute highly promising candidates. The present study thus aimed to investigate the potential of five terrestrial microalgal strains to increasingly produce the carotenoids β-carotene, canthaxanthin and astaxanthin when being exposed to UV-A stress. Light stress experiments were performed using a novel irradiation system based on UV-LED technology. Microalgal cultures were treated with UV-A radiation to stimulate carotenogenesis and the time-dependent effects were investigated by high-performance liquid chromatography analysis. The potential of the microalgae to enhance de novo biosynthesis of the targeted metabolites under the influence of UV-A light could be confirmed by significantly increased yields of canthaxanthin in four out of five strains and by a significantly enhanced β-carotene concentration in at least one strain during 72 h of investigation. Overall, the results provided evidence that UV-A light stress can be effective in rapidly inducing carotenogenesis in terrestrial microalgae and thus harbors vast potential for further exploitation regarding large-scale carotenoid production.
Fractal water structures affected by softener agent in cotton cloths
Authors: Yagihara Shin , Saito Hironobu , Sugimoto Hironori , Kawaguchi Tsubasa , Fukuzaki Minoru , Igarashi Takako , Hoshi Masato , Nakamura Koichi 
Published: July 2022

AbstractBroadband dielectric spectroscopy (BDS) measurements were performed on cotton cloth samples with softener agents in natural environments, and a recent analytical technique of fractal analysis refined in dielectric spectroscopy was used for water structures. Three relaxation processes observed in the GHz, MHz, and kHz regions were attributed to the dynamic behaviors of hydrogen-bonding networks (HBNs) of water and interacting molecules, hydrated polymer chains, and ions restricted in the interfaces of large structures. Fractal analysis of the GHz region suggested that the GHz frequency process was retained, even in the dry state, revealing a broad spatial distribution of HBN fragments of various sizes. This typical tendency for heterogeneous hydration in cotton cloth was emphasized by the addition of a softener agent, as the value of Cole–Cole’s relaxation time distribution parameter changed from 0.55 to 0.41. The addition of the softener agent still retained the GHz frequency process, even in the dry state. This result means that the softener inhibited the formation of hydration sites on the cellulose surface and induced the dispersion of hydration sites. Thus, HBNs are fragmented by the softener agent. On the other hand, water molecules still aggregate to retain HBNs in a restricted area. The heterogeneous dispersion of HBN fragments broadens the GHz relaxation process, and the lower-frequency tail overlaps with the lower relaxation process because of chain dynamics with interacting water molecules. The structure formed by these water molecules, which is restricted by polymer chains and related to the stiffening effect of cotton fabric, is also heterogeneously hindered by the appropriate concentration of the softening agent. These indications were also consistent with the T2 relaxation time obtained using the Carr–Purcell–Meiboom–Gill method of nuclear magnetic resonance measurements and are consequently reflected in the hydration model for macroscopic properties of cotton fabric.
Graphical abstract
Effects of world knowledge on the prediction of upcoming verbs: an eye-tracking study
Authors: Vela-Candelas Juan , Català Natàlia , Demestre Josep 
Published: July 2022

AbstractSome theories of sentence processing make a distinction between two kinds of meaning: a linguistic meaning encoded at the lexicon (i.e., selectional restrictions), and an extralinguistic knowledge derived from our everyday experiences (i.e., world knowledge). According to such theories, the former meaning is privileged over the latter in terms of the time-course of its access and influence during on-line language comprehension. The present study aims to examine whether world knowledge anomalies (that do not violate selectional restrictions) are rapidly detected during online sentence processing. In an eye-tracking experiment, we used materials in which the likelihood of a specific verb (entrevistar or secuestrar, the Spanish translations for to interview and to kidnap) depended on the agent of the event (periodista or terrorista, the Spanish translations for journalist and terrorist). The results showed an effect of typicality in regression path duration and total reading times at both the verb region and the spillover region, thus providing evidence that world knowledge is rapidly accessed and used during on-line sentence comprehension.
Peer Educators in the Facilitation of Sexuality and Respectful Relationship Education for People with an Intellectual Disability: A Scoping Review and Narrative Synthesis
Authors: James Michelle H. , Porter Joanne E. , Kattel Sumitra , Prokopiv Valerie , Hopwood Peter 
Published: July 2022

AbstractA scoping review was conducted to identify how peer-education models are being used in sexuality and respectful relationship education for people with a disability. The search was conducted in August 2021 using the Joanna Briggs framework to scope and map the literature and research activity. Using strict criteria, 7 online databases, grey literature and reference lists were searched for resources written or published in the last 15 years (2006–2021). Relevant sources were shortlisted and assessed by the two authors. Six sources met the criteria for inclusion in this review. In total, four educational programs are described and discussed. The results identify four sexuality and respectful relationship programs that met screening criteria: (1) “Telling it like it is!”, (2) “Sexual Lives and Respectful Relationships”, (3) “Talking about sex and relationships: the views of young people with learning disabilities”, and (4) “Health, Safety & Sexuality Training for You & Me”. Peer-educators experienced increased confidence and feelings of empowerment, while people without an intellectual disability reported a greater understanding of the challenges and experiences of people with a disability. The use of peer educators to deliver sexuality and respectful relationship education for people with intellectual disability is a promising education model with multiple potential benefits for participants. However, more research is needed to understand the consequences and limitations of such programs.
Effective Forchheimer Coefficient for Layered Porous Media
Authors: Lenci Alessandro , Zeighami Farhad , Di Federico Vittorio 
Published: July 2022

AbstractInertial flow in porous media, governed by the Forchheimer equation, is affected by domain heterogeneity at the field scale. We propose a method to derive formulae of the effective Forchheimer coefficient with application to a perfectly stratified medium. Consider uniform flow under a constant pressure gradient $$\Delta P/L$$

Δ
P
/
L

in a layered permeability field with a given probability distribution. The local Forchheimer coefficient $$\beta$$
β
is related to the local permeability k via the relation $$\beta =a/k^c$$

β
=
a
/

k
c

, where $$a>0$$

a
>
0

being a constant and $$c\in [0,2]$$

c
∈
[
0
,
2
]

. Under ergodicity, an effective value of $$\beta$$
β
is derived for flow (i) perpendicular and (ii) parallel to layers. Expressions for effective Forchheimer coefficient, $$\beta _e$$

β
e

, generalize previous formulations for discrete permeability variations. Closed-form $$\beta _e$$

β
e

expressions are derived for flow perpendicular to layers and under two limit cases, $$F\ll 1$$

F
≪
1

and $$F\gg 1$$

F
≫
1

, for flow parallel to layering, with F a Forchheimer number depending on the pressure gradient. For F of order unity, $$\beta _e$$

β
e

is obtained numerically: when realistic values of $$\Delta P/L$$

Δ
P
/
L

and a are adopted, $$\beta _e$$

β
e

approaches the results valid for the high Forchheimer approximation. Further, $$\beta _{e}$$

β
e

increases with heterogeneity, with values always larger than those it would take if the $$\beta - k$$

β
-
k

relationship was applied to the mean permeability; it increases (decreases) with increasing (decreasing) exponent c for flow perpendicular (parallel) to layers. $$\beta _{e}$$

β
e

is also moderately sensitive to the permeability distribution, and is larger for the gamma than for the lognormal distribution.
Mapping the research on the legacy of socialism, individual attitudes, and entrepreneurship: a bibliometric analysis and future research agenda
Authors: Nguyen Lanh Thi , Nguyen-Quoc Anh , Dung Bui Thi Kim 
Published: July 2022

AbstractStudies on the interconnection between the legacy of socialism, individual attitudes, and entrepreneurship have increased considerably and have formed a new, dynamic, and rapidly growing field of research. However, the field remains largely unorganized and conflicting, making it challenging to take stock of the literature systematically. Our review explores the key trends, patterns, and internal knowledge structure of this emerging research stream. An innovative methodological approach that combines three bibliometric techniques (citation analysis, co-citation analysis, and co-occurrence analysis) and qualitative content analysis is applied. We identify the evolution, the most impactful journals, research, authors, and research contexts in the field. We also indicate the emergence of several academic conversations within the research stream and the critical arguments expressed in them. Research gaps and an agenda for further research are then discussed.
Characterization of the Immune Infiltration Landscape and Identification of Prognostic Biomarkers for Esophageal Cancer
Authors: Chen Yuanmei , Huang Xinyi , Chen Lin , Weng Guibin , Huang Zhengrong , Zhang Yangfan , Xiao Tianya , Chen Junqiang , Zhu Kunshou , Xu Yuanji 
Published: July 2022

AbstractImmunotherapy is an effective treatment for esophageal cancer (ESCA) patients. However, there are no dependable markers for predicting prognosis and immunotherapy responses in ESCA. Our study aims to explore immune gene prognostic models and markers in ESCA as well as predictors for immunotherapy. The expression profiles of ESCA were obtained from The Cancer Genome Atlas (TCGA), the Gene Expression Omnibus (GEO), and International Cancer Genome Consortium (ICGC) databases. Cox regression analysis was performed to construct an immune gene prognostic model. ESCA was grouped into three immune cell infiltration (ICI) clusters by CIBERSORT algorithm. The immunotherapy response of patients in different ICI score clusters was also compared. The copy number variations, somatic mutations, and single nucleotide polymorphisms were analyzed. Enrichment analyses were also performed. An immune gene prognostic model was successfully constructed. The ICI score may be used as a predictor independent of tumor mutation burden. Enrichment analyses showed that the differentially expressed genes were mostly enriched in microvillus and the KRAS and IL6/JAK/STAT3 pathways. The top eight genes with the highest mutation frequencies in ESCA were identified and all related to the prognosis of ESCA patients. Our study established an effective immune gene prognostic model and identified markers for predicting the prognosis and immunotherapy response of ESCA patients.
Clinical course of Coronavirus Disease-19 in patients with haematological malignancies is characterized by a longer time to respiratory deterioration compared to non-haematological ones: results from a case–control study
Authors: Oliva A. , Curtolo A. , Volpicelli L. , Cancelli F. , Borrazzo C. , Cogliati Dezza F. , Marcelli G. , Gavaruzzi F. , Di Bari S. , Ricci P. , Turriziani O. , Mastroianni C. M. , Venditti M. 
Published: July 2022

Abstract
Background
We evaluated clinical features and risk factors for mortality in patients with haematological malignancies and COVID-19.

Methods
Retrospective, case–control (1:3) study in hospitalized patients with COVID-19. Cases were patients with haematological malignancies and COVID-19, controls had COVID-19 without haematological malignancies. Patients were matched for sex, age and time of hospitalization.

Results
Overall, 66 cases and 198 controls were included in the study. Cases had higher prior corticosteroid use, infection rates, thrombocytopenia and neutropenia and more likely received corticosteroids and antibiotics than controls. Cases had higher respiratory deterioration than controls (78.7% vs 65.5%, p = 0.04). Notably, 29% of cases developed respiratory worsening > 10 days after hospital admission, compared to only 5% in controls. Intensive Care Unit admission and mortality were higher in cases than in controls (27% vs 8%, p = 0.002, and 35% vs 10%, p < 0.001).
At multivariable analysis, having haematological malignancy [OR4.76, p < 0.001], chronic corticosteroid therapy [OR3.65, p = 0.004], prior infections [OR57.7, p = 0.006], thrombocytopenia [OR3.03, p < 0.001] and neutropenia [OR31.1, p = 0.001], low albumin levels [OR3.1, p = 0.001] and ≥ 10 days from hospital admission to respiratory worsening [OR3.3, p = 0.002] were independently associated with mortality.
In cases, neutropenia [OR3.1, p < 0.001], prior infections [OR7.7, p < 0.001], ≥ 10 days to respiratory worsening [OR4.1, p < 0.001], multiple myeloma [OR1.5, p = 0.044], the variation of the CT lung score during hospitalization [OR2.6, p = 0.006] and active treatment [OR 4.4, p < 0.001] all were associated with a worse outcome.

Conclusion
An underlying haematological malignancy was associated with a worse clinical outcome in COVID-19 patients. A prolonged clinical monitoring is needed, since respiratory worsening may occur later during hospitalization.
Integrative analysis of LncRNA-mRNA signature reveals a functional LincRNA in triple-negative breast cancer
Authors: Jia Yan , Jia Yongsheng , Shi Yehui , Zhao Weipeng , Martin Jérôme , Wang Xiaorui , Tong Zhongsheng , Song Yueshuai 
Published: July 2022

Abstract
Purpose
Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer. It is still unclear that the mechanisms by which long non-coding RNA (lncRNA) regulates tumorigenesis of TNBC. In this study, we explored the function and regulation of lncRNA in TNBC.

Methods
The differentially expressed and overlapped lncRNAs were obtained from two microarray datasets of breast cancer. The cancer genome atlas (TCGA) data was applied to validate the roles of top differentially expressed lncRNAs. The potential relationship among lncRNAs, miRNAs, and mRNAs and the effects of them on the TNBC tumorigenesis were further explored through multiple bioinformatic methods.

Results
Long intergenic non-protein coding RNA 1351 (LINC01351) was first discovered to play an oncogenic role in TNBC. The highly expressed LINC01351 was significantly related to aggressive subtypes, advanced stages and metastasis of breast cancer. The overexpressed LINC01351 was associated with adverse prognosis of patients with TNBC. LINC01351 was found to negatively regulate ELK4 which was involved in the transcriptional regulation in cancer. The high expression of ELK4 showed favorable prognosis of patients with basal-like 1 subtype and luminal androgen receptor subtype of TNBC.

Conclusion
The dysregulation of LINC01351 played an important role in triple-negative breast cancer. LINC01351 could be a poor prognostic marker and a potential target for patients with TNBC.
Resource Recommendation Based on Industrial Knowledge Graph in Low-Resource Conditions
Authors: Liu Yangshengyan , Gu Fu , Gu Xinjian , Wu Yijie , Guo Jianfeng , Zhang Jin 
Published: July 2022

AbstractResource recommendation is extremely challenging under low-resource conditions because representation learning models require sufficient triplets for their training, and the presence of massive long-tail resources leads to data sparsity and cold-start problems. In this paper, an industrial knowledge graph is developed to integrate resources for manufacturing enterprises, and we further formulate long-tail recommendations as a few-shot relational learning problem of learning-to-recommend resources with few interactions under low-resource conditions. First, an industrial knowledge graph is constructed based on the predesigned resource schema. Second, we conduct schema-based reasoning on the schema to heuristically complete the knowledge graph. At last, we propose a multi-head attention-based meta relational learning model with schema-based reasoning to recommend long-tail resources under low-resource conditions. With the IN-Train setting, 5-shot experimental results on the NELL-One and Wiki-One datasets achieve average improvements of 28.8 and 13.3% respectively, compared with MetaR. Empirically, the attention mechanism with relation space translation learns the most important relations for fast convergence. The proposed graph-based platform specifies how to recommend resources using the industrial knowledge graph under low-resource conditions.
Expansion properties of double standard maps
Authors: BENEDICKS MICHAEL , MISIUREWICZ MICHAL , RODRIGUES ANA 
Published: July 2022

AbstractFor the family of double standard maps
$f_{a,b}=2x+a+({b}/{\pi }) \sin 2\pi x \pmod {1}$
we investigate the structure of the space of parameters a when
$b=1$
and when
$b\in [0,1)$
. In the first case the maps have a critical point, but for a set of parameters
$E_1$
of positive Lebesgue measure there is an invariant absolutely continuous measure for
$f_{a,1}$
. In the second case there is an open non-empty set
$E_b$
of parameters for which the map
$f_{a,b}$
is expanding. We show that as
$b\nearrow 1$
, the set
$E_b$
accumulates on many points of
$E_1$
in a regular way from the measure point of view.
Effect of Sea‐Level Change on River Avulsions and Stratigraphy for an Experimental Lowland Delta
Authors: Chadwick A. J. , Steele S. , Silvestre J. , Lamb M. P. 
Published: July 2022

AbstractLowland deltas experience natural diversions in river course known as avulsions. River avulsions pose catastrophic flood hazards and redistribute sediment that is vital for sustaining land in the face of sea‐level rise. Avulsions also affect deltaic stratigraphic architecture and the preservation of sea‐level cycles in the sedimentary record. Here, we present results from an experimental lowland delta with persistent backwater effects and systematic changes in the rates of sea‐level rise and fall. River avulsions repeatedly occurred where and when the river aggraded to a height of nearly half the channel depth, giving rise to a preferential avulsion node within the backwater zone regardless of sea‐level change. As sea‐level rise accelerated, the river responded by avulsing more frequently until reaching a maximum frequency limited by the upstream sediment supply. Experimental results support recent models, field observations, and experiments, and suggest anthropogenic sea‐level rise will introduce more frequent avulsion hazards farther inland than observed in recent history. The experiment also demonstrated that avulsions can occur during sea‐level fall—even within the confines of an incised valley—provided the offshore basin is shallow enough to allow the shoreline to prograde and the river to aggrade. Avulsions create erosional surfaces within stratigraphy that bound beds reflecting the amount of deposition between avulsions. Avulsion‐induced scours overprint erosional surfaces from sea‐level fall, except when the cumulative drop in sea‐level is greater than the channel depth and less than the basin depth. Results imply sea‐level signals outside this range are removed or distorted in delta deposits.