bluuebunny/crossref_metadata_2025_split huggingface dataset:
The nonlinear vibration and dispersive wave systems with extended homoclinic breather wave solutions
Authors: Rao Xianqing , Manafian Jalil , Mahmoud K. H. , Hajar Afandiyeva , Mahdi Ahmed B. , Zaidi Muhaned 
Published: August 2022

Abstract
This article investigates the extended homoclinic (heteroclinic) breather wave solutions and interaction periodic and dark soliton solutions to the nonlinear vibration and dispersive wave systems. The solutions include periodic, breather, and soliton solutions. The bilinear form is considered in terms of Hirota derivatives. Accordingly, we utilize the Cole–Hopf algorithm to obtain the exact solutions of the (

2
+
1

2+1

)-dimensional modified dispersive water-wave system. The analytical treatment of extended homoclinic breather wave solutions and interaction periodic and dark soliton solutions are studied and plotted in four forms of density plots. A nonlinear vibration system will be studied. Employing appropriate mathematical assumptions, the novel kinds of the extended homoclinic breather wave solutions and interaction periodic and dark soliton solutions are derived and constructed in view of the combination of kink, periodic, and soliton for an extended homoclinic breather and also a combination of two kinks, periodic and dark soliton in terms of exponential, trigonometric, hyperbolic functions for interaction periodic and dark soliton of the governing equation. To achieve this, the illustrative example of the (

2
+
1

2+1

)-D modified dispersive water-wave system is furnished to demonstrate the feasibility and reliability of the procedure applied in this research. The trajectory solutions of the traveling waves are offered explicitly and graphically. The effect of the free parameters on the behavior of designed figures of a few obtained solutions for two nonlinear rational exact cases was also considered. By comparing the suggested scheme with the other existing methods, the results state that the execution of this technique is succinct, extensive, and straightforward.
Auf die Beziehungen kommt es an! Die Analyse sozialer Netzwerke in der Sportwissenschaft
Authors: Wäsche Hagen 
Published: August 2022

Zusammenfassung
Das Ziel dieses Beitrags ist es, den Anwendungsbereich und Nutzen der sozialen Netzwerkanalyse (SNA) für die sportwissenschaftliche Forschung herauszuarbeiten sowie die Grundlage eines sportwissenschaftlichen Forschungsprogramms darzustellen. Dazu findet zunächst eine theoretische Einordung des Netzwerkbegriffs im Zusammenhang von sozialen Strukturen und sozialem Handeln statt. Im Anschluss werden die wichtigsten theoretischen und methodischen Konzepte der SNA vorgestellt. Schließlich werden zentrale Themen und Fragestellungen netzwerkanalytischer Forschung in der Sportwissenschaft diskutiert. Dies geschieht mittels einer sechsdimensionalen Typologie von sozialen Netzwerken im Sport, welche eine systematische Betrachtung des Forschungsfeldes erlaubt. Anhand verschiedener Beispiele zu den Netzwerktypen werden die Bandbreite sportwissenschaftlicher Netzwerkforschung aufgezeigt sowie zukünftige Herausforderungen und Möglichkeiten verdeutlicht.
Individualisierte Athletenentwicklung als komplexe Managementaufgabe in Stützpunktnetzwerken des Leistungssports: Zur Programmentwicklung der PRIO-Intervention
Authors: Mayer Jochen , Kühnle Felix , Dörnenburg Luisa , Thiel Ansgar 
Published: August 2022

ZusammenfassungDie Schaffung optimaler Rahmenbedingungen für eine möglichst individualisierte Athletenentwicklung stellt Leistungssportorganisationen vor vielschichtige Herausforderungen. Im vorliegenden Beitrag begründen wir das Design eines Organisationsentwicklungsprogramms zur Förderung der individualisierten Athletenentwicklung (PRIO-Intervention), welches derzeit im Netzwerk aus dem Olympiastützpunkt und Bundesstützpunkten der Metropolregion Rhein-Neckar implementiert, evaluiert und optimiert wird. Im Rahmen theoretischer Überlegungen wird zunächst gezeigt, dass Athletenentwicklung ein komplexer biopsychosozialer Prozess ist, der neben der Förderung sportmotorischer Höchstleistung auch die nachhaltige Gesunderhaltung und konstruktive Bewältigung alltäglicher Lebensaufgaben beinhaltet. Vor diesem Hintergrund konzipieren wir individualisierte Athletenentwicklung als Managementaufgabe in Stützpunktnetzwerken des Leistungssports, die einen angemessenen Umgang mit Heterogenität, Interdisziplinarität und Flexibilität erfordert. Zudem wird die praktische Relevanz von partizipativen Ansätzen aus dem Bereich der Organisationsentwicklung verdeutlicht. Auf dieser Basis stellen wir die Konzeption der PRIO-Intervention vor, die im Kern aus drei vernetzten Phasen (Hear-, Create-, Deliver-Phase) und einem prozessbegleitenden multi-stakeholder Koordinierungsteam besteht. Dieser Ansatz soll insbesondere den Athletinnen und Athleten die Möglichkeit geben, sich aktiv an der Entwicklung von Lösungen zur Optimierung ihres Stützpunktnetzwerks zu beteiligen. Durch die Evaluierung des Implementierungsprozesses lassen sich zudem neue Erkenntnisse über die Möglichkeiten und Grenzen partizipationsbasierter Interventionen der Organisationsentwicklung im Leistungssport gewinnen.
The relationship between serum vitamin D and antibody response following two doses of inactivated COVID-19 vaccine
Authors: Öztürk Reyhan , Yılmaz Niyazi Samet , Ulukanlıgil Mustafa 
Published: August 2022

Abstract

Objectives
Low vitamin D levels are associated with the severity and mortality of COVID-19 infection. Nevertheless, the relationship between the 25-hydroxyvitamin D [25(OH)D] levels and the antibody response following COVID-19 vaccination is not fully elucidated. Herein, we explored the relationship between SARS-CoV-2 IgG (sCOVG) and 25(OH)D.

Methods
In this prospective observational case-control study, we used an automated chemiluminescent immunoassay method to measure sCOVG and 25(OH)D levels in 96 patients 28 days following the second dose of inactivated vaccine. We considered the positivity for sCOVG at three different index values: 1, 2.42, and 7. We classified 25(OH)D levels between 0 and 20 ng/mL as vitamin D deficiency, 21–29 ng/mL as insufficiency and 30 ng/mL as sufficiency.

Results
Median sCOVG index was 6.02 (interquartile ranges 3.41–11.63) and median 25(OH)D level was 11.5 ng/mL (interquartile ranges 10–17). We could not find a significant correlation between 25(OH)D and sCOVG levels (Spearman’s rho, r=0.175, p=0.12). When considering the variables categorically, we did also not conclude significant relationships between adequate or inadequate antibody responses in patients with deficient, insufficient, and sufficient 25(OH)D by three sCOVG cut-off index values (1, 2.42, and 7) (Chi-square test, p=0.8, 0.29, and 0.08, respectively).

Conclusions
The relevant literature is limited on the association between the antibody response to COVID-19 vaccines and vitamin D levels. Although the previous research suggested conflicting findings of the response to mRNA vaccines, we could not conclude a significant relationship between sCOVG and 25(OH)D levels 28 days after two doses of inactivated COVID-19 vaccine.
Synthesis of chiral binaphthol-based bishydroxylamines
Authors: Kleinheider André , Lamm Jan-Hendrik , Neumann Beate , Stammler Hans-Georg , Mitzel Norbert W. 
Published: August 2022

Abstract
Although bishydroxylamines have been widely used in chemistry, very little has been reported on corresponding chiral representatives. In this paper, we present the synthesis of two chiral binaphthyl-based bishydroxylamines with different substitution patterns at their NOH functions. The key step of the synthesis involves the reduction of the corresponding dinitrone compounds. The molecular structure in the solid state of one of the nitrone precursors is presented.
The Effects of Training Interventions on Modifiable Hamstring Strain Injury Risk Factors in Healthy Soccer Players: A Systematic Review
Authors: Schneider Celine , Van Hooren Bas , Cronin John , Jukic Ivan 
Published: August 2022

ABSTRACT
Despite promising research on various soccer-specific injury prevention programs, hamstring strain injuries (HSIs) persist in being a major problem in the sport. Therefore, in an attempt to expand the current knowledge on the prevention of HSIs, this systematic review aimed to identify how modifiable risk factors for HSIs (hamstring strength, hamstring:quadriceps [H:Q] strength ratios, biceps femoris long head fascicle length, and hamstring angle of peak torque) were altered following various training interventions. The protocol was preregistered on PROSPERO (CRD42020177363). The literature search was conducted on PubMed, SportDISCUS, and Web of Science. Following the search process, 20 studies were included in the systematic review, and the methodological quality of these studies was reported. Interventions were categorized based on exercise characteristics (movement velocity and contraction type), and the effects of each intervention subgroup were analyzed separately for all proposed risk factors for HSIs. Our findings show that a broad variety of exercise types (i.e., high- and low-velocity movements, eccentric only and traditional exercises) improves all risk factors for HSIs compared with fewer exercise types. Therefore, these findings suggest that hamstring injury risk factors can best be modified using a wide variety of exercises compared with, for example, only 1 or 2 specific exercises.
m6A is required for resolving progenitor identity during planarian stem cell differentiation
Authors: Dagan Yael , Yesharim Yarden , Bonneau Ashley R , Frankovits Tamar , Schwartz Schraga , Reddien Peter W , Wurtzel Omri 
Published: August 2022

AbstractRegeneration and tissue homeostasis require accurate production of missing cell lineages. Cell production is driven by changes to gene expression, which is shaped by multiple layers of regulation. Here, we find that the ubiquitous mRNA base‐modification, m6A, is required for proper cell fate choice and cellular maturation in planarian stem cells (neoblasts). We mapped m6A‐enriched regions in 7,600 planarian genes and found that perturbation of the m6A pathway resulted in progressive deterioration of tissues and death. Using single‐cell RNA sequencing of >20,000 cells following perturbation of the m6A pathway, we identified an increase in expression of noncanonical histone variants, and that inhibition of the pathway resulted in accumulation of undifferentiated cells throughout the animal in an abnormal transcriptional state. Analysis of >1,000 planarian gene expression datasets revealed that the inhibition of the chromatin modifying complex NuRD had almost indistinguishable consequences, unraveling an unappreciated link between m6A and chromatin modifications. Our findings reveal that m6A is critical for planarian stem cell homeostasis and gene regulation in tissue maintenance and regeneration.
Identification and characterization of in vitro expanded hematopoietic stem cells
Authors: Che James L C , Bode Daniel , Kucinski Iwo , Cull Alyssa H , Bain Fiona , Becker Hans J , Jassinskaja Maria , Barile Melania , Boyd Grace , Belmonte Miriam , Zeng Andy G X , Igarashi Kyomi J , Rubio‐Lara Juan , Shepherd Mairi S , Clay Anna , Dick John E , Wilkinson Adam C , Nakauchi Hiromitsu , Yamazaki Satoshi , Göttgens Berthold , Kent David G 
Published: August 2022

AbstractHematopoietic stem cells (HSCs) cultured outside the body are the fundamental component of a wide range of cellular and gene therapies. Recent efforts have achieved > 200‐fold expansion of functional HSCs, but their molecular characterization has not been possible since the majority of cells are non‐HSCs and single cell‐initiated cultures have substantial clone‐to‐clone variability. Using the Fgd5 reporter mouse in combination with the EPCR surface marker, we report exclusive identification of HSCs from non‐HSCs in expansion cultures. By directly linking single‐clone functional transplantation data with single‐clone gene expression profiling, we show that the molecular profile of expanded HSCs is similar to proliferating fetal HSCs and reveals a gene expression signature, including Esam, Prdm16, Fstl1, and Palld, that can identify functional HSCs from multiple cellular states. This “repopulation signature” (RepopSig) also enriches for HSCs in human datasets. Together, these findings demonstrate the power of integrating functional and molecular datasets to better derive meaningful gene signatures and opens the opportunity for a wide range of functional screening and molecular experiments previously not possible due to limited HSC numbers.
Test-to-Stay After SARS-CoV-2 Exposure: A Mitigation Strategy for Optionally Masked K-12 Schools
Authors: Campbell Melissa M. , Benjamin Daniel K. , Mann Tara K. , Fist Alex , Blakemore Ashley , Diaz Kylee S. , Kim Hwasoon , Edwards Laura J. , Rak Zsolt , Brookhart M. Alan , Moore Zack , Tilson Elizabeth Cuervo , Kalu Ibukun , Boutzoukas Angelique E. , Moorthy Ganga S. , Uthappa Diya , Scott Zeni , Weber David J. , Shane Andi L. , Bryant Kristina A. , Zimmerman Kanecia O. 
Published: August 2022

OBJECTIVES
We evaluated the impact of a test-to-stay (TTS) program on within-school transmission and missed school days in optionally masked kindergarten through 12th grade schools during a period of high community severe acute respiratory syndrome coronavirus 2 transmission.

METHODS
Close contacts of those with confirmed severe acute respiratory syndrome coronavirus 2 infection were eligible for enrollment in the TTS program if exposure to a nonhousehold contact occurred between November 11, 2021 and January 28, 2022. Consented participants avoided school exclusion if they remained asymptomatic and rapid antigen testing at prespecified intervals remained negative. Primary outcomes included within-school tertiary attack rate (test positivity among close contacts of positive TTS participants) and school days saved among TTS participants. We estimated the number of additional school-acquired cases resulting from TTS and eliminating school exclusion.

RESULTS
A total of 1675 participants tested positive or received at least 1 negative test between days 5 and 7 and completed follow-up; 92% were students and 91% were exposed to an unmasked primary case. We identified 201 positive cases. We observed a tertiary attack rate of 10% (95% confidence interval: 6%–19%), and 7272 (89%) of potentially missed days were saved through TTS implementation. We estimated 1 additional school-acquired case for every 21 TTS participants remaining in school buildings during the entire study period.

CONCLUSIONS
Even in the setting of high community transmission, a TTS strategy resulted in substantial reduction in missed school days in optionally masked schools.
Analysis of sequence polymorphism of OsHKT1;5 gene in rice (Oryza sativa L.)
Authors: Huy Duong Nguyen , Xuan An Tran , Phuc Do Thi 
Published: August 2022

In salt stress conditions, the excessive accumulation of Na+ ion in the cytoplasm could cause ion toxicity, metabolic imbalances, and reduction in growth of plant. The ability of maintaining a low Na+ concentrations or low Na+/K+ ratio in cytosol plays the important roles of plant adapt to salinity stress. In rice, the HKT transporter family has been proven to be critical for salt tolerance and the maintenance of Na+, K+ homeostasis under salinity conditions. In this study, we conducted the sequence polymorphisms analysis in the OsHKT1;5 coding region in order to detect the potential allelic variants in some local rice cultivars in Viet Nam. The exon 1 region and exon 2-3 region of OsHKT1;5 gene were amplified by PCR in two separate reactions. After direct sequencing of PCR products, the full length coding region of OsHKT1;5 gene was obtained and compared to reference Nipponbare OsHKT1;5 coding sequence. Accordingly, twelve nucleotide substitutions in coding sequence of OsHKT1;5 were identified, including six non-synonymous substitutions (G382A, C418G, G551A, C994G, C1183G, A1630C) and the other six synonymous substitutions (G225A, C1038G, G1152A, G1261A, G1304C, C1608T). Further analysis revealed that six non-synonymous substitutions (G382A, C418G, G551A, C994G, C1183G, A1630C) caused the changes in amino acids (D128N, P140A, R184H, H332D, V395L, and S544R). The single nucleotide polymorphism A1630C leading substitution of S544R was newly found in the Chiem Rong cultivar. In silico analysis of protein structure and post-translational modifications indicated that amino acid substitutions had no influence on protein structure but led to changes in post-translational modifications such as phosphorylation and SUMOylation.
KESIAPAN BELAJAR MANDIRI KONTRIBUSINYA PADA PRESTASI BELAJAR MATAKULIAH STENOGRAFI MAHAMAHASISWA ANGKATAN 2011 KLS A PADA PROGRAM STUDI PENDIDIKAN MANAJEMEN PERKANTORAN
Authors: Supardi Endang 
Published: August 2022

Penelitian ini dilakukan pada Mahasiswa Angkatan 2011 Kls A Pada Program Studi Pendidikan Manajemen Perkantoran Universitas Pendidikan Indonesia.Permasalahan yang menjadi kajian dalam penelitian ini adalah rendahnya prestasi belajar stenografi Mahasiswa Angkatan 2011 Kls A Pada Program Studi Pendidikan Manajemen Perkantoran. Bukti empiris masalah tersebut dapat dilihat dari rendahnya nilai ujian akhir semester (UAS) yang berada di bawah kriteria kelulusan. Nilai ini menjadi sebuah gambaran dan juga merupakan sebuah tolak ukur dalam tingkat keberprestasian belajar. Penelitian ini terdiri dari dua variabel yaitu minat kesiapan belajar mandiri (X) dan prestasi belajar mahasiswa (Y). Tujuan penelitian ini adalah untuk memperoleh gambaran tingkat minat kesiapan belajar mandiri, tingkat prestasi belajar mahasiswa, dan juga untuk mengetahui apakah ada hubungan antara minat kesiapan belajar mandiri dengan prestasi belajar stenografi Mahasiswa Pendidikan Manajemen Perkantoran Angkatan 2011 Kelas A.Metode yang digunakan dalam penelitian ini adalah laporan penelitian-verifikatif dengan teknik survey, dengan teknik pengumpulan data melalui penyebaran angket, skala pengukuran yang digunakan yaitu ratting scale, angket dikumpulkan dari responden dengan ukuran populasi 47 Mahasiswa Angkatan 2011 Kls A Pada Program Studi Pendidikan Manajemen Perkantoran. Teknik analisis data yang digunakan dalam penelitian ini adalah uji koefiesien kontingensi.Berdasarkan prestasi penelitian, peneliti mendapatkan informasi bahwa tingkat minat kesiapan belajar mandiri berada pada kategori sedang dan tingkat prestasi belajar mahasiswa berada pada kategori sedang. Dari prestasi uji hipotesis diperoleh bahwa terdapat hubungan positf dan signifikan antara tingkat minat kesiapan belajar mandiri mahasiswa dengan tingkat prestasi belajar Mahasiswa Angkatan 2011 Kls A Pada Program Studi Pendidikan Manajemen Perkantoran
The Role of Quality of Academic Information Systems and Facilities on Student Loyalty
Authors: Sianipar Milka Rositi , Pakpahan Efendy , Manalu Putranto 
Published: August 2022

Abstract: The growth of quality standards, as well as, higher student demands has implications for higher education to improve service quality to be able to provide satisfaction that leads to increased student loyalty.Research aims: This study determines the effect of academic information systems and facilities on student loyalty at the Faculty of Economics, Universitas Prima Indonesia through satisfaction as an integral variable.Design/Methodology/Approach: Data analysis using path analysis, and feasibility test of the model with the Smartpls 3.0 program. The population in this study were all 5th term students of Management Undergraduate Degree and Accounting Undergraduate Degree. The number of samples was determined using the Krejcie-Morgan table so that 291 people were selected.Research findings: The results showed that the academic information system had a significant positive effect on student loyalty through satisfaction, so that the satisfaction variable mediates the academic information system on student loyalty (t-statistic = 2.131 ( t-table): p-value = 0.034). Likewise, the effect of facilities on student loyalty through satisfaction as an intervening variable that shows a significant value (t-statistic = 2,220 ( t-table): p-value = 0.027).Theoretical contribution/Originality:. The novelty of this research is that increasing student loyalty can be done by improving academic information system services and adequate campus facilities.Practitioner/Policy implication: The university management must provide quality facilities and infrastructure to increase student loyalty.
Protocols of Standard of Care for Adult Patients with Primary Antibody Deficiencies Will Improve Timing of Diagnosis, Survival, and Quality of Life
Authors: Napiórkowska-Baran Katarzyna , Więsik-Szewczyk Ewa , Ziętkiewicz Marcin , Matyja-Bednarczyk Aleksandra , Kołtan Sylwia , Bąkowska-Kocik Natalia , Rosada Tomasz , Baranowska Karolina , Alska Ewa , Tykwińska Marta , Szynkiewicz Ewa , Zacniewski Robert , Bartuzi Zbigniew 
Published: August 2022

The majority of primary immunodeficiencies (PIDs) are antibody deficiencies (PADs), and not all of them are rare diseases; As an example, Caucasian individuals suffer from selective IgA deficiency at a frequency of 1:500.In addition to infections, symptomatic patients with PAD are more likely to develop neoplastic, autoimmune, and allergic diseases. In the event that PAD is neglected or delayed for more than ten years, complications develop, eventually resulting in death. No studies have been conducted to devise and report detailed ready-to-use protocols for managing PAD to date.This study aimed to propose protocols and guidelines for the adult PAD patients’ standard care. Preparing the protocol, we considered the frequency and type of laboratory tests, imaging, endoscopic examinations, specialist consultations, and standardized recommendations for further care in the place of residence. As a result of the proposed monitoring scheme, patients can be provided with complete care in terms of their underlying conditions and comorbidities, as well as early detection of complications. This protocol will serve as a guide for physicians dealing with these patients and enable comparisons of patient groups across a variety of treatment centers, even far away from each other. A national consultant in the field of clinical immunology verified the protocol mainly developed by Polish experts from reference immunology centres for adults.