bluuebunny/crossref_metadata_2025_split huggingface dataset:
Establishing Minimal Clinically Important Differences for the Quality of Life Instrument in Patients With Breast Cancer QLICP-BR (V2.0) Based on Anchor-Based and Distribution-Based Methods
Authors: Li Fei , Liu Yuxi , Wan Chonghua , Zhou Jiali , Tan Jianfeng , Chen Huanwei 
Published: May 2022

ObjectiveTo determine the minimal clinically important differences (MCIDs) for the breast cancer scale QLICP-BR (V2.0) among the Quality of Life Instruments system for cancer patients (QLICP), which consist of the general module of 32 items classifying into 4 domains and the specific module of 10 items.MethodsAccording to the scoring rule of QLICP-BR (V2.0), the scores of each domain and the overall scale were calculated. The MCIDs of this scale were established by anchor-based and distribution-based methods. The anchor method used the Q29 item in the EORTC QLQ-C30 scale as anchors and defined the treatment effectiveness of the anchor-based method using criteria A (one level improvement after treatment) and B (at least one level improvement after treatment), while methods of effect size (ES), standard error of measurement (SEM), and reliability change index (RCI) were used in distribution-based methods.ResultsUsing the anchor-based method, according to standard A, the MCIDs of the physical domain (PHD), psychological domain (PSD), social domain (SOD), common symptoms and side effect domain (SSD), core/general module (CGD), specific domain (SPD), and the total score (TOT) were 16.24, 11.37, 11.31, 12.07, 11.49, 10.69, and 11.23 respectively; according to standard B, the MCIDs of PHD, PSD, SOD, SSD, CGD, SPD, and TOT were 18.88, 15.14, 14.10, 14.50, 13.93, 12.17, and 14.23 respectively. In the distribution-based MCID study, when ES = 0.8, the MCID values of each domain and the total score of the scale were 9.14, 10.34, 8.34, 10.54, 6.79, 9.73, and 6.96 respectively. The MCIDs calculated when a SEM of 1.96 was used as the intermediary index were 8.38, 11.04, 8.67, 10.00, 7.44, 9.83, and 7.81. The MCIDs calculated when a RCI of 1.96 was used as the intermediary index were 11.84, 15.61, 12.27, 14.14, 10.52, 13.90, and 11.05. Additionally, the MCID value calculated by the two standards of the anchor method was similar to 0.8 ES, 1.96 SEM, and 1.96 RCI.ConclusionUsing the anchor-based method, 0.8ES, 1.96SEM, and 1.96RCI have a better effect on the minimal clinically important difference of breast cancer scale and were recommended to be the preferred methods for establishing MCID.
Estrogen Metabolite 2-Methoxyestradiol Attenuates Blood Pressure in Hypertensive Rats by Downregulating Angiotensin Type 1 Receptor
Authors: Zhang Yong , Ogola Benard O. , Iyer Laxmi , Karamyan Vardan T. , Thekkumkara Thomas 
Published: May 2022

The therapeutic potential of 2-Methoxyestradiol (2ME2) is evident in cardiovascular disease. Our laboratory has previously demonstrated the mechanism involved in the 2ME2 regulation of angiotensin type 1 receptor (AT1R) in vitro. However, 2ME2 regulation of angiotensin receptors and its effects on blood pressure (BP) and resting heart rate (RHR) are uncertain. In this study, male and female Wistar-Kyoto (WKY) rats infused with angiotensin II (65 ng/min) and male spontaneously hypertensive rats (SHR) were surgically implanted with telemetric probes to continuously assess arterial BP and RHR. In both male and female WKY rats, 2ME2 treatment (20 mg/kg/day for 2 weeks) resulted in a significant reduction of Ang II-induced systolic, diastolic, and mean arterial BP. Moreover, significant weight loss and RHR were indicated in all groups. In a separate set of experiments, prolonged 2ME2 exposure in male SHR (20 mg/kg/day for 5 weeks) displayed a significant reduction in diastolic and mean arterial BP along with RHR. We also found downregulation of angiotensin receptors and angiotensinogen (AGT) in the kidney and liver and a reduction of plasma Ang II levels. Collectively, we demonstrate that 2ME2 attenuated BP and RHR in hypertensive rats involves downregulation of angiotensin receptors and body weight loss.
Mental Health Literacy Programs for Parents of Adolescents: A Systematic Review
Authors: Kusaka Sakurako , Yamaguchi Satoshi , Foo Jerome Clifford , Togo Fumiharu , Sasaki Tsukasa 
Published: May 2022

IntroductionMany mental illnesses begin during adolescence. Parents of adolescents need to have sufficient mental health literacy (MHL) to recognize mental health problems in their children and to assist them with help-seeking. Although several educational programs have been developed to enhance parental MHL, their effectiveness has not been established. This study provides a systematic review for the effectiveness of MHL programs in parents of adolescents.MethodsPubMed, PsycINFO, CINAHL, ERIC and Web of Science were searched from the earliest date possible until February 2022; references of studies which met eligibility criteria were also screened. Studies that assessed quantitative change in at least one of the following components of parental MHL were included: knowledge of mental health/illnesses; stigma toward people with mental health problems; confidence in helping children with mental health problems, and intention, knowledge or behavior of helping children with mental health problems. Risk of bias (ROB) for each outcome within the included studies was rated using the revised Cochrane risk-of-bias tool for randomized trials for randomized controlled trials (RCTs), and the Risk of Bias Assessment Tool for Nonrandomized Studies for nonrandomized studies.ResultsNine studies (four RCTs, three controlled before-and-after studies, and two case series), reported in 10 articles, were included. Mental health knowledge and/or confidence was significantly improved in several studies, while no studies observed significant improvement in stigma and/or intention/behavior of helping children. ROB was high in five out of nine studies (10 out of 18 outcomes) and unclear in the others.ConclusionsA limited number of studies have evaluated effects of MHL program in parents and inconsistent quality contributes to difficulty in establishing their overall effectiveness. More studies with appropriate methods of recruitment, measurement and analysis, and transparent reporting are needed.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42020193072, Identifier: CRD42020193072.
Policy Goals of Contract Arrangements in Primary Care in Jeopardy: A Cross-Sectional Consumer Satisfaction Survey of Community Residents in Hangzhou, China
Authors: Ren Lixian , Ren Jianping , Liu Chaojie , He Mengyan , Qiu Xiantao 
Published: May 2022

ObjectiveChina is attempting to establish a voluntary contracting system in primary care. This study aimed to determine the degree of consumer satisfaction with the entitlements of contract arrangements and its associated factors.MethodsA stratified cluster sampling strategy was adopted to recruit study participants from three administrative districts of Hangzhou municipality, each containing six residential communities. In each community, 50 households were recruited. A questionnaire was administered through face-to-face interviews with members of the households who signed a contract with community health centers, to collect data regarding their sociodemographic characteristics, health conditions, and knowledge of and attitudes toward the contract entitlements. Consumer satisfaction was measured using six items rated on a five-point Likert scale ranging from “1=very dissatisfied” to “5=very satisfied” and a summed score was calculated. A mixed linear regression model was established to identify individual predictors of consumer satisfaction after adjustment of the random (intercept) effect of household clusters.ResultsOverall, the respondents reported low levels of awareness and understanding of the contract entitlements, with an average knowledge score of 8.21 (SD = 3.74) out of a maximum possible of 19. The respondents had relatively lower levels of satisfaction (satisfied or very satisfied) with their prioritized entitlements (51.5%) and hospitals at home and telemedicine services (31.3%), compared with the contract and insurance policies (85.5%) and medical services provided (87.0%). Female gender, older age, chronic conditions, and perceived better health were associated with higher levels of satisfaction, while poor awareness and knowledge were associated with lower levels of satisfaction.ConclusionThe study participants perceived limited benefits from the contract arrangements in primary care, which may jeopardize the policy purpose of the arrangements to encourage patients to use primary care as the first contact point in accessing health care services. It is evident that consumer satisfaction with the contract entitlements varies by healthcare needs. Lower levels of satisfaction are associated with poor awareness and knowledge of the entitlements.
Multi-Variate LSTM Prediction of Alaska Magnetometer Chain Utilizing a Coupled Model Approach
Authors: Blandin Matthew , Connor Hyunju K. , Öztürk Doğacan S. , Keesee Amy M. , Pinto Victor , Mahmud Md Shaad , Ngwira Chigomezyo , Priyadarshi Shishir 
Published: May 2022

During periods of rapidly changing geomagnetic conditions electric fields form within the Earth’s surface and induce currents known as geomagnetically induced currents (GICs), which interact with unprotected electrical systems our society relies on. In this study, we train multi-variate Long-Short Term Memory neural networks to predict magnitude of north-south component of the geomagnetic field (|BN|) at multiple ground magnetometer stations across Alaska provided by the SuperMAG database with a future goal of predicting geomagnetic field disturbances. Each neural network is driven by solar wind and interplanetary magnetic field inputs from the NASA OMNI database spanning from 2000–2015 and is fine tuned for each station to maximize the effectiveness in predicting |BN|. The neural networks are then compared against multivariate linear regression models driven with the same inputs at each station using Heidke skill scores with thresholds at the 50, 75, 85, and 99 percentiles for |BN|. The neural network models show significant increases over the linear regression models for |BN| thresholds. We also calculate the Heidke skill scores for d|BN|/dt by deriving d|BN|/dt from |BN| predictions. However, neural network models do not show clear outperformance compared to the linear regression models. To retain the sign information and thus predict BN instead of |BN|, a secondary so-called polarity model is utilized. The polarity model is run in tandem with the neural networks predicting geomagnetic field in a coupled model approach and results in a high correlation between predicted and observed values for all stations. We find this model a promising starting point for a machine learned geomagnetic field model to be expanded upon through increased output time history and fast turnaround times.
Assessment of the Impact of the Covid-19 Pandemic on the Balance of Payments and the International Investment Position of Russia
Authors: Petrikova E. M. 
Published: May 2022

The article analyzes the current situation in the world economy in 2020, caused by the energy crisis due to the failure of OPEC agreements, political conflicts, trade wars, and the COVID-19 pandemic. The pandemic and its socio-economic consequences have become the main cause of the global crisis.The author conducted statistical analysis of the effects of the COVID-19 pandemic on the balance of payments and the international investment position of Russia, which in aggregate form reveals the results of the country's foreign economic activity. The author analyzes country's external sector statistics summarizing the results of Russia's activities with the rest of the world in 2020 and identifies the trends of the impact of the coronavirus pandemic on the Russian economy and the results of the foreign economic activity of the Russian state. The paper analyzes in detail all the enlarged items of the balance of payments and the international investment position of the Russian Federation and quantifies the impact of the COVID-19 pandemic in 2020–2021 on them and also provides an overview of the development of the external sector of the Russian economy at the end of the year.While analyzing the statistical data of the balance of payments and the international investment position of Russia in 2000–2021, a comparison is made with the current situation in the economy and foreign economic sphere in connection with the global crisis of 2008 and the introduction of international financial and economic sanctions after 2014. The author with regard to the effects of the COVID-19 coronavirus pandemic on the balance of payments and the international investment position of the Russian Federation in 2020–2021 substantiates a forecast of further prospects for the development of the foreign economic sector of the Russian economy in the medium term.
Birth Seasonality in Russia: Regional Features
Authors: Rodionova L. A. , Kopnova E. D. 
Published: May 2022

In the article based on statistical methods the authors evaluateinterregional differences in seasonality of births in Russia and attempt toexplain the differences in the seasonality of the number of births in the regions of Russia. The relevance of these issues is explained by the need to monitor changes in demographic indicators following the implementation of national projects for the period up to the mid-2020s.The authors considered the most fundamental results of some domestic and foreign studies on this subject. Some hypotheses regarding the causes of the seasonality of births were tested using econometric tools (based on official birth statistics in the regions of the Russian Federation for the period 2006–2020).The statistically significant factors that form the amplitude of seasonal fluctuations were the degree of urbanization, income and the climate based on the OLS model. The amplitude of fluctuations in births decreased with an increase in the level of urbanization (growth in the share of the urban population) and the population of the region. An increase in January temperature increased the amplitude of birth fluctuations. The positive impact of income on the amplitude of the fluctuation was explained by the active planning of the timing of childbearing in high-income regions, but further research was needed. Nutritional characteristics were found to be statistically insignificant factors. The number of marriages took a special place in the formation of the seasonality of births. On the whole for the Russian Federation, based on time series models, a cointegration relationship between the number of marriages and the number of births was found. This relationship had begun to weaken over the past five years.
C-axis texture of high-rate-sputtered Nd2Fe14B thin films: independence of sheet texture of Mo underlayer
Authors: Tsuchida Takayuki , Fukushima Jun , Saito Shin , Hayashi Yamato , Takizawa Hirotsugu 
Published: May 2022

Abstract
In this study, we investigated the effects of the sheet texture of the Mo underlayer on the c-axis texture of the high-rate-sputtered Nd2Fe14B phase. The magnetic properties revealed that the squareness of the Nd–Fe–B magnetic layer did not depend on the sheet texture of the Mo underlayer but on the substrate temperature: large squareness was obtained when the magnetic layer was sputtered at high substrate temperature above 500 °C. In-plane X-ray diffraction measurements indicated that the intensity of diffraction from the Nd2Fe14B (410) plane did not depend on the sheet texture of the Mo underlayer but on the substrate temperature: high intensity was obtained when the magnetic layer was sputtered at above 500 °C, which was consistent with magnetic properties. These results support that the c-axis texture of the high-rate-sputtered magnetic layer was driven by the c plane with the lowest surface energy among the crystal planes in the Nd2Fe14B phase.
Tunable mid-infrared ultra-narrowband plasmonic absorber and sensor based on bulk Dirac semimetal metamaterials
Authors: Wang Chen-Hao , Huang Kai , Ma Rui , Liu Gui-Dong , Wang Ling-Ling , Lin Qi 
Published: May 2022

Abstract
We propose a tunable mid-infrared ultra-narrowband plasmonic absorber and sensor based on bulk Dirac semimetal metamaterials, which is hypersensitive to the varation of background refractive index. Based on the tunable characteristic of bulk Dirac semimetal, the absorption wavelength can be dynamically adjusted without re-optimizing the geometric parameters, meanwhile, perfect absorption can be maintained despite the equal scale variation of the structure. The absorption bandwidth is so tiny that the sensitivity and figure of merit can be up to 16 000 nm RIU−1 and 3500 RIU−1, respectively. Our results may open up new avenues for the design of optical filter and bio-chemical sensing.
Social Support Affecting Personal Health Practices among Nursing Students
Authors: Peninoy Danielle , Suherman Hezekiah , Vingco Aldie , Rey Kristel Anne M. 
Published: May 2022

Nursing students are trained to promote healthy practices among clients but it does not necessarily mean that they are applying it to themselves. As healthcare providers, nursing students offer support to clients in the promotion of healthy lifestyle. However, there is limited literature exploring the types of social support that nursing students have and its relationship to personal health practices. The purpose of this study was to determine personal health practices among nursing students and its relationship to social support. This cross-sectional study was conducted on 163 nursing students from two universities in Cavite and Pasay and selected using purposive sampling. They answered self-report questionnaires including the perceived social support scale and personal health practices. Data were analyzed by statistical tests of Spearman Rank correlation coefficient. The results revealed a high level of social support with a mean of 3.78(SD = 0.62) and moderate personal health practices with a mean of 3.15 (SD = 0.31). Although there is no significant relationship between the general perceived social support and personal health practices, emotional support showed a positive relationship with personal health practices (p = 0.004). Students’ score in health practices does not differ significantly considering gender, but significant differences are found when age is considered (p = 0.01).
The Relationship Between Knowledge and Behavior of Healthy Clean Living Order of Households in Rw 17 Village Cihideung Subdistrict Of Parongpong West Bandung Regency
Authors: Maulita Pola , Hondo Florida 
Published: May 2022

Households with PHBS in West Java were still low so that people at high risk of experiencing health problems. The purpose of this study was to determine the relationship between knowledge and behaviour regarding the household in order PHBS RW 17 Village Sub-district Cihideung Parongpong West Bandung Regency. This research used descriptive method of correlation. Fifty-two mothers were chosen through simple random sampling technique. The instrument used was a questionnaire sheet containing 12 questions about knowledge and 12 statements about behavior (PHBS). The results showed that the knowledge of respondents about the PHBS is good. PHBS household often washes hands after bowel movement, and seldom do not use PAM/gallon water for cooking and drinking in RW 17 Village Cihideung. There is no significant relationship between knowledge and behavior of living clean and healthy household order.
Principais tipos de feridas em cuidados paliativos
Authors: Oliveira Pedro Gonçalves de 
Published: May 2022

O conceito de cuidados paliativos tem enfatizado a pessoa doente, incluindo suas necessidades especiais e de sua famí­lia, e não mais somente o órgão comprometido, a idade ou o tipo de doença em questão. Feridas constituem um grande problema no final da vida, afetando quase um terço dos pacientes em cuidados paliativos, fato agravado pelas dificuldades em seu manejo devido ao desconforto do paciente e í natureza geralmente complexa dessas lesões. Sendo assim, o objetivo do presente trabalho foi relacionar os principais tipos de feridas presentes no contexto dos cuidados paliativos, de modo a contribuir com a compreensão deste cenário e com a identificação e desenvolvimento de medidas adequadas para o seu manejo. Trata-se de uma revisão narrativa da literatura que abrangeu o perí­odo compreendido entre 1998 e 2018. Foram utilizadas as bases LILACS, SCIELO e PUBMED, empregando-se os descritores em saúde "cicatrização de feridas" e "cuidados paliativos", posteriormente complementados especificamente para cada lesão. Os resultados foram agrupados e apresentados conforme mecanismos e caracterí­sticas de cada tipo de lesão, destacando-se lesões por pressão, suspeita de lesão tecidual profunda e feridas neoplásicas, entre outras. As informações apresentadas neste trabalho relevaram-se úteis para a melhor compreensão do cenário que envolve feridas em cuidados paliativos, assim como sua identificação, diferenciação e manejo, conforme caracterí­sticas, limitações e necessidades especí­ficas.
Tratamento de paciente com úlceras venosas com surepress® e coberturas interativas: relato de caso
Authors: Costa Lara Mendes Chaer Rezende , Reis Elisângela Soares da Silva , Castro Natália Ferreira Gonçalves Perdigão de , Aleixo Viviane Pereira , Vieira Cláudia Patrí­cia , Rocha Cleideana Cristina Vieira , Borges Daniela Tinti Moreira , Nascimento Filho Hélio Martins do 
Published: May 2022

CONFLITO DE INTERESSE Os autores informam o seguinte conflito de interesse: A SurePress® é comercializada na Clí­nica BIOVEIN Medicina Integrada, de propriedade de uma das pesquisadores e também onde outro dos pesquisadores presta serviço.
Objetivo: realizar tratamento de paciente com três úlceras venosas em membro inferior direito há sete anos de acordo com as recomendações cientí­ficas disponí­veis na literatura. Método: Trata-se de um estudo descritivo de natureza aplicada desenvolvido em serviço de tratamento de pacientes com ferida. Resultado: com dois meses de assistência baseada em evidências cientí­ficas houve a cicatrização das lesões. Conclusão: a assistência transdisciplinar com embasamento cientí­fico diminui o tempo do tratamento, seu custo, potencializa a cicatrização das feridas com impacto positivo na qualidade de vida do doente.
Eficácia da prata tópica na redução da área de feridas infectadas - uma revisão sistemática
Authors: Cabral Silva Andrey Victor , Teixeira Caires Thaianne Fernanda 
Published: May 2022

Objetivo: Comparar os efeitos dos do uso de prata tópica versus curativos sem prata na redução da área de feridas infectadas. Tendo em vista o surgimento, nos últimos anos, dos curativos de prata no tratamento de feridas, tornando válido o levantamento das evidências sobre esse fato. Método: Este trabalho é uma revisão sistemática norteada pelas diretrizes do Prisma, utilizando a base de dados MedLine/Pubmed, SciELO e busca manual. Ensaios clí­nicos randomizados em inglês, português e espanhol foram incluí­dos, comparando tratamentos com prata tópica e sem prata na redução da exsudação da área de feridas infectadas. O CONSORT foi utilizado como método de avaliação da qualidade dos artigos, incluindo os com pontuação de pelo menos 70%. Resultados: foram encontrados quatro estudos que contemplam objetivos. Todos apresentaram superioridade em favor do uso de prata devido í diminuição da área da ferida. Os principais riscos de viés considerados são os de desgaste, publicação, detecção e desempenho. Conclusão: O tratamento com prata mostrou-se superior ao tratamento com curativos que não utilizam prata na redução da área lesada em queimaduras, feridas cirúrgicas, úlceras, pés diabéticos e infectados. Entretanto, estudos com maior valor amostral ainda são necessários para esclarecer uma melhor abordagem.