bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH SENAM LANSIA DALAM PENINGKATAN FUNGSI KOGNITIF KELOMPOK LANSIA DI BALAI PELAYANAN PENYANTUNAN LANJUT USIA (BPPLU) BENGKULU
Authors: Pardosi Sariman , Marsinova Derison 
Published: February 2022

Pembangunan nasional di segala bidang yang selama ini telah dilaksanakan oleh pemerintah, telah mampu meningkatkan derajat kesehatan masyarakat secara umum antara lain dapat dilihat dari menurunnya angka kematian ibu dan bayi serta meningkatnya angka umur harapan hidup. Berdsarkan Susenas tahun 2014 jumlah lansia di Indonesia mencapai 20,24 juta jiwa setara dengan 8.03% dari jumlah penduduk Indonesia. Jumlah lansia perempuan lebih banyak daripada laki-laki, 10,77 juta lansia dibandingkan dengan 9,47 juta laki-laki dan diproyeksikan pada tahun 2020 akan meningkat sebesar 11,34% (BPS, 2014).
Pemberian latihan olahraga pada usia lanjut dimulai dengan intensitas dan waktu yang ringan kemudian meningkat secara pelahan-lahan serta tidak bersifat kompetitif/ bertanding. Latihan olahraga bagi manula mempunyai manfaat besar karena dapat meningkatkan kemampuan aerobik yaitu akan meningkatkan aliran dan volume pasokan darah yang membawa oksigen ke organ-organ tubuh terutama ke organ otak. Hal ini didukung oleh penelitian selama 10 tahun pada pria usia lanjut berdasarkan data dari Finlandia, Italia dan Belanda oleh B.M. Van Gelder dan kawan-kawan (2004) tentang hubungan aktifitas fisik dengan penurunan kognitif. Penelitian tersebut menyimpulkan bahwa penurunan intensitas dan durasi aktifitas akan mempercepat proses penurunan fungsi kognitif.
Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian pre eksperiment dengan rancangan penelitian yang digunakan one group pre and post test. yaitu sampel pada penelitian ini diobservasi terlebih dahulu sebelum diberi perlakuan, kondisi setelah diberikan perlakuan sampel. Analisis dilakukan dengan univariat dan analisis bivariat. Sebelum uji statistik, dilakukan terlebih dahulu dilakukan uji normalitas data dengan uji Kolmogorof Smirnov yang dikumpulkan kemudian di tentukan uji statistik yang akan dilakukan dengan uji Wilcoxon bertujuan untuk mengetahui dampak dari perlakuan terhadap nilai MMSE setelah senam lansia dengan tingkat kepercayaan 95% atau nilai ? = 0,05.
Hasil penelitian menunjukan bahwa responden lansia menurut tingkat pendidikan sebanyak 16 orang atau 80% dengan tingkat pendidikan SD, dan menurut umur minimal 60 tahun dan maksimal 84 tahun nilai mean MMSE untuk pre senam lansia sebesar 21,70 dan nilai mean MMSE untuk post senam lansia sebesar 25,35, terjadi peningkatan nilai mean sebesar 3,65. Nilai p value 0,001 < 0,05 dapat disimpulkan bahwa ada pengaruh senam lansia terhadap peningkatan kognitif lansia
PENGARUH PENDIDIKAN KESEHATAN MENGGUNAKAN MEDIA VIDEO TERHADAP KESIAPAN IBU HAMIL DALAM MENGHADAPI PERSALINAN
Authors: Lisnawati Lisnawati , Linggar Adi Prahastuti Dara 
Published: February 2022

Problems : The indirect cause of maternal death is that there are still many late cases. Case 3 is late, including: being late in recognizing the danger signs of childbirth and making decisions, being referred too late to a health facility, being late being handled by health workers at a health service facility. Readiness in the face of childbirth is one solution to prevent maternal death. The aim of the research: to determine the effect of health education using video media on the readiness of pregnant women in facing childbirth in the working area of ??UPTD Puskesmas Talun, Cirebon Regency. Method: The research design used a quasi-experimental design with pretest and posttest with one group design. The sampling technique was carried out by non-probability sampling technique. Sampling used a total sampling technique (30 pregnant women) in the second and third trimesters. Bivariate analysis using Wilcoxon test. Results: The results of the pre test and post test showed an increase. The effect of health education using video media on mother's readiness in facing childbirth (p value = 0.000). Conclusion: There is an effect of health education using video media on the readiness of pregnant women in facing childbirth.

Keywords: Health Education Using Video Media, Readiness, Pregnant Women
Response of white clover cultivars to sheep and beef cattle grazing management across three pastoral environments in New Zealand.
Authors: Jahufer Zulfi , HESLOP Angus , COUSINS Greig , Woodfield Derek , Ford John 
Published: February 2022

White clover (Trifolium repens L.) is the main legume component in temperate perennial pasture swards in New Zealand. Developing broadly adapted cultivars is an important objective in white clover breeding programs. Field trials across years, seasons, locations and grazing environments, help breeders select superior material, and assess the merit of new cultivars available to farmers. This paper is based on results from analysis of data from field trials across three locations in New Zealand: Kerikeri (cattle grazed), Palmerston North (cattle grazed) and Lincoln (sheep grazed), evaluating 44 experimental varieties and 16 cultivars for seasonal growth and leaf size. We report on performance of the 16 cultivars across the three locations.
Significant genotype-by-environment interactions were estimated for seasonal growth and leaf size. The importance of conducting multi-location and year evaluation trials under cattle and sheep grazing management methods (rotational/set stocking) was demonstrated. Among the 16 cultivars, Legacy showed above average performance across all 3 locations. Hilltop when compared among similar leaf size material, showed above average seasonal growth across years under rotational sheep grazing management during the first 4 years of the trial at Lincoln. Hilltop also showed above average seasonal growth under set socking with sheep in years 5 and 6 at Lincoln.
A summary of research results on pasture responses to fertiliser and lime in the South Island hill and high country
Authors: Morton Jeff 
Published: February 2022

The published results from trials used to determine nutrient and lime requirements of legume-based pastures in South Island hill and high country are summarised. Most of the research in the 1950’s and 1960’s found that sulphur (S) alone was required on the less weathered and leached Semi-arid and Pallic soils but both S and phosphorus (P) were required on the more weathered and leached Brown soils. The severe lack of S necessitated the application of rapidly plant-available S as gypsum. Research in the 1970’s and 1980’s determined the most effective particle size ranges in relation to frequency of application of elemental S to provide adequate S. This work highlighted a need for sufficient S for legume growth before a growth response to P was measured on most soils which has resulted in the manufacture of a range of suitable sulphur fortified superphosphate products. During this 40-year period a limited amount of work showed that nitrogen (N) fertiliser could enhance the growth of resident grasses and legumes and that added S could improve the response. Molybdenum (Mo) has been the only trace element that has been lacking for pasture growth and research has been reported that defines optimal rates, frequency of application and criteria for interpretation. In the last 20 years, the need lime to alleviate soil aluminium (Al) toxicity on these mainly acidic soils has been demonstrated to allow legumes to establish and persist.
Current gaps in available information indicate potential areas for more research. These gaps include identifying responses to rates of P and S on pasture with varying legume content on different hill slopes, differential application of elemental sulphur and lime on shady aspects of Semi-Arid and Pallic soils, definition of P and S requirements of pure legume swards, the role of fertiliser N to improve legume establishment, fertiliser and management options to break down thatch at the soil surface and improve legume establishment, determination of the soil and landscape factors that affect the spatial variability of soil Al concentrations, further confirmation of the role of lime injection into soil layers with high soil Al toxicity, the assessment of test strips of applied Mo to assist in the identification of deficiencies in legumes and the combination of information into a decision support system to aid farmers in their selection of legume species and fertiliser and lime requirements for different areas of their farms.
Growth rates and persistence of annual and perennial clovers
Authors: Olykan Sonya , Lucas Richard , Hunter Stuart , Moot Derrick 
Published: February 2022

This study quantified the temporal productivity of monocultures of four annual and two perennial clover species in a summer dry environment at Lincoln University, Canterbury, New Zealand. Clovers were ungrazed in the first year to enable natural re-establishment of the annuals, but grazed in the second year.
In 2019 clover cultivar affected (P<0.001) yield in early spring (24th September) with ‘Viper’ balansa (Trifolium michelianum) producing 5.0 t DM/ha compared (P<0.05) with 3.5 t for ‘Arrotas’ arrowleaf (T. vesiculosum), 3.2 t for ‘Antas’ and ‘Woogenellup’ sub clovers (T. subterraneum), 1.6 t for ‘Kopu’ white clover (T. repens) and 1.2 t for ‘Relish’ red clover (T. pratense). ‘Arrotas’ grew 111 kg DM/ha/d from 14th to 28th August, ‘Viper’ grew 123 kg DM/ha/d from 28th August to 24th September and then 183 kg DM/d to 9th October.
After a dry autumn in 2020, ‘Kopu’ white and ‘Relish’ red persisted, but only sub clovers ‘Napier’ and ‘Woogenellup’ successfully re-established. By 17th September, accumulated dry matter yield (t) differed with ‘Woogenellup’ sub (4.3) and ‘Relish’ red (3.7) producing more than ‘Kopu’ white (2.8) and ‘Napier’ sub (2.2). ‘Woogenellup’ sub clover grew at 72 kg/ha/day from 20th August to 17th September, which was more than twice the rate of the other clovers (~30 kg/ha/day). These four clovers continued to provide grazable herbage through the second year.
In 2020 the re-establishment of arrowleaf, balansa and Persian (T. resupinatum) clovers was poor, and each yielded <0.5 t/ha by 17th September, with their plots dominated by weeds. These results confirm monocultures of top flowering annual clovers are productive in their first year but poor re-establishment may occur in their second year. They may therefore be best suited as one-year specialised crops for grazing or conserved feed.
The earlier growth profiles of the annual compared with perennial clovers suggests there is potential to increase their use in summer dry environments to meet early spring feed requirements of ewes and lambs.
Quantification and mitigation of nitrogen leaching in a maize silage cropping system
Authors: Tsimba Rowland , Gunn Tania , Densley Raewyn , Williams Ian , Edmeades Greg , Millar Jamie 
Published: February 2022

Nitrogen (N) leaching is a major source of groundwater contamination. We used a series of lysimeters and suction cups to measure total N leaching losses in a high N maize crop system on a long-term maize paddock in the Waikato.
The goal of the study was to 1) quantify N leaching losses under maize silage, 2) determine the effectiveness of a cut-and-carry annual ryegrass catch crop (RG) in mitigating N leaching losses and 3) determine an appropriate depth for measuring N leaching losses under maize.
At least 200 kg/ha more fertiliser N than calculated plant requirements was applied to the maize crop to ensure surplus soil N after maize.
Nitrogen leaching losses were measured in a maize-RG and maize-fallow rotation over two seasons (October 2018 - September 2020). Less than 10 % of N leaching losses occurred during the maize growing season. This is likely due to evapotranspiration exceeding rainfall in summer.
The greatest leaching losses were observed in the maize-fallow rotation, averaging 60 kg N/ha and 88 kg N/ha for the 2018/19 and 2019/20 seasons. This was despite 2020 winter being drier than 2019. The greater 2019/20 leaching losses can be attributed to a greater soil N concentration (+15 mg N/L) in 2020.
The importance of catch crops as a N leaching mitigation tool after maize was evident over the two years, resulting in leaching reductions >85% in the maize-RG than the maize–fallow plots. The catch crop removed >200 kg N/ha from the soil, significantly reducing the soil N concentration, which appear to be the main driver of leaching losses in our study. Additionally, RG also increased gravimetric soil water content by 7.3 % in the top 30 cm.
When N leaching was measured at 70 cm, losses in fallow plots were almost three times higher than the 41.6 kg N/ha recorded at the 120 cm soil depth, our default maize rooting depth.
A similar amount of isotopic 15N (1.2 %) was observed in maize grain at maturity when 15N was inserted to 60 cm or 120 cm soil depth. This was greater than the background values obtained when standard urea was applied to the plots (0.37 %), indicating 15N interception at depth.
It is speculated that provided fertiliser rates match crop N demand and catch crops are used, N leaching losses in maize crops should be much lower than values reported here, irrespective of soil type and season.
Oscillatory Behaviors of microRNA Networks: Emerging Roles in Retinal Development
Authors: Fishman Elizabeth S. , Han Jisoo S. , La Torre Anna 
Published: February 2022

A broad repertoire of transcription factors and other genes display oscillatory patterns of expression, typically ranging from 30 min to 24 h. These oscillations are associated with a variety of biological processes, including the circadian cycle, somite segmentation, cell cycle, and metabolism. These rhythmic behaviors are often prompted by transcriptional feedback loops in which transcriptional activities are inhibited by their corresponding gene target products. Oscillatory transcriptional patterns have been proposed as a mechanism to drive biological clocks, the molecular machinery that transforms temporal information into accurate spatial patterning during development. Notably, several microRNAs (miRNAs) -small non-coding RNA molecules-have been recently shown to both exhibit rhythmic expression patterns and regulate oscillatory activities. Here, we discuss some of these new findings in the context of the developing retina. We propose that miRNA oscillations are a powerful mechanism to coordinate signaling pathways and gene expression, and that addressing the dynamic interplay between miRNA expression and their target genes could be key for a more complete understanding of many developmental processes.
Targeting ApoC3 Paradoxically Aggravates Atherosclerosis in Hamsters With Severe Refractory Hypercholesterolemia
Authors: Xu Yitong , Guo Jiabao , Zhang Ling , Miao Guolin , Lai Pingping , Zhang Wenxi , Liu Lili , Hou Xinlin , Wang Yuhui , Huang Wei , Liu George , Gao Mingming , Xian Xunde 
Published: February 2022

RationaleApoC3 plays a central role in the hydrolysis process of triglyceride (TG)-rich lipoproteins mediated by lipoprotein lipase (LPL), which levels are positively associated with the incidence of cardiovascular disease (CVD). Although targeting ApoC3 by antisense oligonucleotide (ASO), Volanesorsen markedly reduces plasma TG level and increase high-density lipoprotein cholesterol (HDL-C) in patients with hypertriglyceridemia (HTG), the cholesterol-lowering effect of ApoC3 inhibition and then the consequential outcome of atherosclerotic cardiovascular disease (ASCVD) have not been reported in patients of familial hypercholesterolemia (FH) with severe refractory hypercholesterolemia yet.ObjectiveTo investigate the precise effects of depleting ApoC3 on refractory hypercholesterolemia and atherosclerosis, we crossed ApoC3-deficient hamsters with a background of LDLR deficiency to generate a double knockout (DKO) hamster model (LDLR−/−, XApoC3−/−, DKO).Approach and ResultsOn the standard laboratory diet, DKO hamsters had reduced levels of plasma TG and total cholesterol (TC) relative to LDLR−/− hamsters. However, upon high-cholesterol/high-fat (HCHF) diet feeding for 12 weeks, ApoC3 deficiency reduced TG level only in female animals without affecting refractory cholesterol in the circulation, whereas apolipoprotein A1 (ApoA1) levels were significantly increased in DKO hamsters with both genders. Unexpectedly, loss of ApoC3 paradoxically accelerated diet-induced atherosclerotic development in female and male LDLR−/− hamsters but ameliorated fatty liver in female animals. Further analysis of blood biological parameters revealed that lacking ApoC3 resulted in abnormal platelet (PLT) indices, which could potentially contribute to atherosclerosis in LDLR−/− hamsters.ConclusionsIn this study, our novel findings provide new insight into the application of ApoC3 inhibition for severe refractory hypercholesterolemia and ASCVD.
Composition Effect on the Pore Structure of Transitional Shale: A Case Study of the Permian Shanxi Formation in the Daning–Jixian Block at the Eastern Margin of the Ordos Basin
Authors: Zhang Qin , Qiu Zhen , Zhao Qun , Zhang Leifu , Dong Dazhong , Wang Yuman , Hou Wei , Li Shuxin , Li Xingtao 
Published: February 2022

Marine–continental transitional (hereinafter referred to as transitional) Permian shales are important targets for shale gas in China because of the considerable volumes of shale gas resources present in them. In this study, transitional shale samples from the Permian Shanxi Formation in the Daning–Jixian block along the eastern margin of the Ordos Basin were collected to investigate the effects of organic and inorganic compositions on the development of their pore structures through organic petrographic analysis, X–ray diffraction, scanning electron microscope (SEM) observation, gas (N2 and CO2) adsorption, high-pressure mercury injection (HPMI), and methane adsorption experiments. The organic petrographic analysis reveals that the Permian Shanxi shale comprises Type-II2-III kerogens, and the average vitrinite reflectance (Ro) is 2.3% at the overmature stage or in the dry gas window. The shale interval at the bottom of the lagoon facies is considered the most favorable interval throughout the entire section because of its high total organic carbon (TOC) content (4.19–43.9%; an average of 16.9%) and high brittle mineral content (38.3–73.2%; an average of 55.8%). N2 and CO2 gas adsorption and HPMI tests reveal the pore size distribution characteristics of the shale. The full pore size distribution by the gas adsorption and HPMI test reveals that micropores (&lt;2 nm) and mesopores (2–50 nm) were dominant in the pore system, and the contributions of the two pore sizes were nearly equivalent, accounting for 21.95–55.05% (an average of 42.3%) and 37.94–64.6% (an average of 49.64%) of the total pore volume, respectively. Additionally, the pore characteristics related to different phases (mainly as silicate, clays, and organic matter) are further clarified by SEM observation and correlation analysis of phase content and pore structure parameters. OM contains numerous SEM-invisible micropores, whereas clay minerals mainly develop mesopores and small macropores (50–100 nm). Furthermore, we calculated the contribution of different shale components to shale porosity. The OM pores account for 0.26–44.1% (an average of 18.7%), and clay mineral pores account for 53.8–93.3% (an average of 76.9%) of the shale porosity. In particular, the OM contributes 73.2% to the surface area and 33.5% to the pore volume. This implies that both OM and clay minerals are important for the storage capacity of adsorbed and free gas.
Research on Failure Precursor Based on Characteristics of Energy Dissipation Rate for Rock
Authors: Liu Xiaohui , Xue Yang , Zheng Yu , Li Hongying 
Published: February 2022

Research on early warning of rock disaster based on the energy theory is closer to the essence of rock failure. In this paper, static compression tests and acoustic emission (AE) tests of coal rock under 0, 8, 16, and 25 MPa confining pressures were carried out on the MTS815 test system. Energy evolution law in the rock failure process was analyzed according to the relationship between mechanical parameters, AE parameters, and energy dissipation rate (EDR) in the rock failure process. Eventually, a new index for evaluating rock failure precursors was proposed based on EDR. The results show that the EDR has a good correlation with mechanical strength and AE events under different confining pressures. The deformation and failure characteristics of coal rock can be truly characterized by EDR. The variation of EDR can be divided into a quiet stage, a stable increasing stage, an active stage, and a stable stage. The EDR level in the quiet stage is obviously enhanced by confining pressure. When EDR reaches the peak, AE events increase rapidly. In the active stage, the EDR peak value is concentrated and large, the AE event is highly active, and stress drops abruptly, indicating that the EDR is reliable for evaluating the rock failure process. Compared with AE test results, it is found that the warning stress and warning time of the EDR failure precursor occur later than that of the AE failure precursor, and the former is closer to the peak stress of rock, which is more universal in engineering and could provide a better reference value for preventing rock disaster.
Deep External Fluid Source Along the Gubbio Normal Fault (Italy): Implications for Slip Along the Altotiberina Active Low-Angle Normal Fault System
Authors: Riegel Hannah , Casale Gabriele , Mirabella Francesco , Hyland Ethan , Talegalli Lorenzo 
Published: February 2022

Fluids play a critical role in fault slip, fault and damage zone development, and the distribution of seismicity in regional fault systems; however, determining the source of fluids within fault damage zones is complicated by superposition of fluid-related fabrics. Clumped isotopes applied to tectonic studies offer an opportunity to distinguish between fluid sources based on temperature and stable isotopic composition. Here we use the clumped isotope geothermometer and field observations and compare them with microstructural analysis to investigate the Gubbio normal-fault (GuF) core, a major SW-dipping epidetachment fault conjugate to the active Altotiberina low-angle normal fault in central Italy. Several distinct calcite vein sets reveal the incorporation of multiple generations of fluids during development of the damage zone. Clumped isotope results from these various precipitation phases record crystallization temperatures ranging from 87–154°C. These temperatures are broadly consistent with the presence of calcite deformation twin types II and III and are higher than estimates of regional peak burial temperatures. Additionally, stable isotope compositions within vein calcite are distinct from published isotopic values of the Apennine sedimentary succession, which constitutes the local bedrock. We propose that these observations suggest hydrothermal fluids migrated from depths greater than 6 km, which requires hydraulic connectivity along structural pathways between the shallow and deep crust, and fluid overpressures. These fluids reach the GuF via migration along the Altotiberina low-angle normal fault plane ​​and they may be either of diagenetic or of deeper subduction origin. We suggest they possibly originated from the proximal retreating Apennine subduction system, implying that subduction processes exert spatial control on the distribution of fluid-assisted normal faulting and related seismicity which is consistent with the co-migration of closely coupled subduction and hinterland extension in the Apennines from Miocene to Present.