bluuebunny/crossref_metadata_2025_split huggingface dataset:
Delivery of Active Medical Management without Dialysis through an Embedded Kidney Palliative Care Model
Authors: Bursic Alexandra E. , Schell Jane O. , Ernecoff Natalie C. , Bansal Amar D. 
Published: July 2022

Key Points

Integrating palliative care into kidney care can lead to improvements in symptom management, advance care planning, and hospice utilization.An embedded kidney palliative care model can enable delivery of active medical management without dialysis to patients whose values align with forgoing dialysis.

Background
Patients with CKD have high symptom burden, low rates of advance care planning (ACP), and frequently receive care that is not goal concordant. Improved integration of palliative care into nephrology and access to active medical management without dialysis (AMMWD) have the potential to improve outcomes through better symptom management and enhanced shared decision making.

Methods
We describe the development of a kidney palliative care (KPC) clinic and how palliative care practices are integrated within an academic nephrology clinic. We performed a retrospective electronic health record (EHR) review for patients seen in this clinic between January 2015 and February 2019 to describe key clinical activities and delivery of AMMWD.

Results
A total of 165 patients were seen in the KPC clinic (139 with CKD and 26 who were already receiving dialysis). Fatigue, mobility issues, and pain were the three most prevalent symptoms (85%, 66%, 58%, respectively). Ninety-one percent of patients had a surrogate decision maker documented in the EHR; 87% of patients had a goals-of-care conversation documented in the EHR. Of the 139 patients with CKD, 67 (48%) chose AMMWD as their disease progressed. Sixty-eight percent (41 of 60) of patients who died during the study were referred to hospice.

Conclusions
Our findings suggest that the integration of palliative care into nephrology can assist in identification of symptoms, lead to high rates of ACP, and provide a mechanism for patients to choose and receive AMMWD. The percentage of patients choosing AMMWD in our study suggests that increased shared decision making may lower rates of dialysis initiation in the United States. Additional prospective research and registries for assessing the effects of AMMWD have the potential to improve care for people living with CKD.
Pengaruh Mata Kuliah Peminatan EduPreneur Terhadap Jiwa Kewirausahaan Mahasiswa
Authors: Wendra Betri , Ariani Lisa , Yusmarni Yusmarni 
Published: July 2022

Abstrak: Tulisan ini merupakan bagian dari penelitian kuantitatif menggunakan metode asosiatif. Teknik pengambilan sampel menggunakan Total Sampling dengan mengambil semua populasi menjadi sampel dimana ada 27 mahasiswa program studi Tadris Matematika angkatan 2018 yang mengambil mata kuliah peminatan Edupreneur. Teknik pengumpulan data dilakukan menggunakan angket dan wawancara. Analisis pada penelitian ini menggunakan Person Product Moment. Korelasi Pearson Product Moment diperoleh nilai sebesar 0,636. Tahapan uji hipotesis dilakukan dengan menafsirkan besaran koefisien korelasi, dalam hal ini menggunakan uji t diperoleh nilai sebesar 4,04. Adapun nilai pada taraf signifikansi 5% adalah sebesar 2,06. Sedemikian sehingga lebih besar dari . Jadi ditolak atau diterima, dengan kata lain terdapat pengaruh mata kuliah peminatan Edupreneur terhadap Jiwa Kewirausahaan Mahasiswa Tadris Matematika Universitas Islam Negeri Sulthan Thaha Saifuddin Jambi.
Abstract: This paper is part of a quantitative research using associative method. The sampling technique used was Total Sampling by taking all the population as samples where there were 27 students of the 2018 department of Tadris Mathematics who took Edupreneur specialization courses. Data collection techniques were carried out using questionnaires and interviews. The analysis in this study uses the Person Product Moment. Pearson Product Moment correlation obtained value of 0.636. At the hypothesis testing stage by interpreting the magnitude of the correlation coefficient using the t test, the value is 4.04. The value of . at the 5% significance level is 2.06. Such that is greater than .. So is rejected or is accepted, in other words, there is an influence of the Edupreneur specialization course on the Entrepreneurial Spirit at department of Tadris Mathematics of the State Islamic University of Sulthan Thaha Saifuddin Jambi.
Problematika Pendidikan Era Pandemi Covid-19: Suatu Kajian Psikologi Dan Implementasinya Bagi Pendidikan Agama Kristen
Authors: Imbing Roy 
Published: July 2022

Latar Belakang : Corona virus mengubah berbagai aspek kehidupan masyarakat saat ini, mulai dari kesehatan, ekonomi dan terkhusus dunia pendidikan. Situasi ini membuat seluruh lapisan pendidikan berpikir keras untuk melanjutkan sisa semester. Tujuan : Menjadi sebuah tatanan perilaku individu dalam peranya sebagai warga Negara. membentuk anak menjadi warga negara yang baik. Metode : Tulisan ini termasuk penelitian kualitatif, yaitu kajian pustaka dari beberapa literature yang berkaitan dengan judul materi serta media-media lainnya seperti berita dari beberapa media online. Penulis menyelidiki problematika pendidikan era pandemic dari sudut pandang psikologi dan implikasinya dalam pendidikan agama Kristen dengan membaca beberapa konsep, teori dan gagasan yang telah dipublikasikan sebelumnya. Hasil : Pengembangan usaha kecil dan mikro syariah, bukan semata-mata langkah yang harus diambil oleh Pemerintah dan hanya menjadi tanggung jawab Pemerintah. Pihak usaha kecil dan mikro syariah sendiri sebagai pihak internal yang dikembangkan, dapat mengayunkan langkah bersama-sama dengan Pemerintah. Karena potensi yang mereka miliki mampu menciptakan kreatifitas usaha dengan memanfaatkan fasilitas yang diberikanoleh pemerintah. Kesimpulan : Sesuai dengan pembahasan materi dan implikasinya terhadap PAK, maka dapat disimpulkan bahwa, pendidikan harus tetap berjalan karena pendidikan adalah kunci untuk membangun pola pikir dan pola hidup naradidik baik secara kognitiif, afektif, psikomotorik dan spiritualitas.
Antibacterial activity of medicinal plants against Streptococcus agalactiae
Authors: Novosak Marina Gisel , Winnik Daniana Lilian , Laczeski Margarita Ester , Quiroga Marina Inés 
Published: July 2022

Streptococcus agalactiae, group B Streptococcus (GBS), infects and causes severe diseases in humans and numerous animal species, including fish, given its ability to cross the host-specific barrier. The emergence of antibiotic resistant GBS strains makes it necessary to look for alternatives to treat and prevent infections that it produces. The aim of the present study was to determine the antibacterial activity of ethanolic and aqueous extracts of medicinal plants from Misiones province, northeast Argentina, against GBS from humans and fish. We used human Streptococcus agalactiae ATCC® BAA-611™ and tilapia Streptococcus agalactiae ATCC® 51487™ strains. Minimum Inhibitory Dose (MID) was determined by the disc diffusion method. Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC), MBC/MIC ratio, drug synergism with commercial antibiotics, and resistance assays were determined with extracts that showed antibacterial activity. Medium Lethal Dose 50 (LD50) was determined by the Artemia salina assay. For ethanolic and aqueous Eugenia uniflora L. extracts, we obtained a MID = 0.5 mg.disc-1. For both extracts of Eugenia uniflora L., the MIC and MBC values were 1 mg.mL-1 and 5 mg.mL-1, respectively. The MICI (MBC/MIC ratio) = 5 qualified the action of these extracts as bacteriostatic. The drug synergism assay with ampicillin, erythromycin, and clindamycin combination and extracts showed indifference. The LD50 of the aqueous extract was 0.82 mg.mL-1 indicating moderate toxicity. This work is a first step to identify chemical compounds in native medicinal plants of Misiones, Argentina, that could mean an alternative for the treatment of Streptococcus agalactiae infections.
Results of Conservative Management of CSF Rhinorrhea in Post Traumatic Patients
Authors: Rana Zubair Mahmood  , Mukhtiyar Ahmed Lakho  , Talha Abbas  , Abdul Wajid  , Touqeer Ahmed  , Umer Farooq  , Sarfraz Khattak  
Published: July 2022

Objectives: We aimed to see the results of conservative management of CSF rhinorrhea in post-traumatic patients.
Material and Methods: An observational study was conducted on 50 patients for 3 months from 1st November 2021 to 31th Jan 2022. Patients presented to neurosurgery unit II, PINS. All patients had a history of road traffic accidents (RTA).
Results: The age range was 10 – 50 years. The mean age was 25 years. All patients were managed conservatively for one week. We advised complete bed rest to all patients for 2 weeks. Head ends of all patients were slightly inclined from 15 – 30 degrees to reduce pressure in basal cisterns. We gave acetazolamide, mannitol, antibiotics, and anti-epileptic medication to all patients. CSF rhinorrhea in our 43 (86%) patients was stopped completely. In our 5 (10%) patients, CSF rhinorrhea was cured completely after doing a lumbar puncture with drainage of CSF and with the placement of a lumbar drain at a rate of 10 ml per hour. In our 2 (4%) patients, CSF rhinorrhea was not cured. We have to do surgery either by trans cranial or endoscopic repair of CSF rhinorrhea.
Conclusion: CSF rhinorrhea is best cured by conservative management except in 4% of cases.
<p>Kesalahan Penggunaan Bahasa Indonesia dalam Karya Tulis Guru SD di Kabupaten Wonosobo (<em>Indonesian Language Errors in Academic Writings Performed by Teachers </em><em>of Elementary Schools in Wonosobo Regency</em>)</p>
Authors: Handono Suryo 
Published: July 2022

Penelitian ini mendeskripsikan kesalahan penggunaan bahasa Indonesia dalam karya tulis guru SD di Kabupaten Wonosobo. Desain penelitian ini adalah kualitatif. Data dikumpulkan dengan teknik dokumentasi dari lima puluh karya tulis guru pada Februari—Maret 2021. Hasil analisis menunjukkan bahwa dalam karya-karya tersebut terdapat kesalahan ejaan, bentuk dan pilihan kata, kalimat, serta paragraf. Kesalahan ejaan terdiri atas penggunaan huruf, penulisan kata, penggunaan tanda baca, dan penulisan unsur serapan. Kesalahan bentuk dan pilihan kata terdiri atas pemakaian bentuk tidak baku, bentuk dasar yang keliru, serta ketaktepatan dan ketakcermatan penggunaan kata untuk melambangkan konsep pikiran. Kesalahan kalimat terdiri atas ketaklugasan, ketaktepatan, ketakjelasan, ketakhematan, dan ketaksejajaran kalimat. Kemudian, kesalahan paragraf terdiri atas ketaksatuan, ketakpaduan, ketaklengkapan, dan ketakruntutan paragraf. This article discusses Indonesian errors in academic writings performed by teachers of elementary schools in Wonosobo Regency, Indonesia. This is a qualitative research. Data were collected using the documentation technique from fifty teachers' papers in February—March 2021. The results of the analysis show that in these works there are errors in spelling, form and choice of words, sentences, and paragraphs. Spelling errors consist of using letters, writing words, using punctuation marks, and writing absorption elements. Misformations and word choice consist of the use of nonstandard forms, wrong basic forms, and inaccuracies and inaccuracies in the use of words to symbolize thought concepts. Sentence errors consist of ambiguity, inaccuracy, ambiguity, inaccuracy, and misalignment of sentences. Then, paragraph errors consist of incompleteness, incoherence, incompleteness, and unorganized paragraph.
Dampak Ekonomi dari Sport Industry, Sport Tourism, dan Sport Science di Era Pasca Pandemi Covid’19
Authors: Purwanti Titik , Ismawati Kun , Aji Ambyah Atas 
Published: July 2022

This research aimed to determine the effect of sport industry, sport tourism, and sport science to the economy in the era of pasca the covid 19 pandemic, both partially and simultaneously. The sampling technique used is by distributing online questionnaire via google form. The population of the research were students from Soloraya and the sample were 215 respondens. The analysis technique used were descriptive statistic; data quality test which includes validity test and reliability test; classic assumption test which includes normality test, multicollonearity test, and heteroscedasticity test; multiple linear regression analysis; determination coefficient test (R2); t-test; and F-test. The results showed that partially, sport industry variable have a not significant effect to the economy in the era of pasca the covid 19 pandemic, but sport tourism and sport science variables have a positive significant effect to the economy in the era of pasca the covid 19 pandemic. All three variables (sport industry, sport tourism, dan sport science) have a significant effect to the economy in the era of pasca the covid 19 pandemic
Formation of Low-mass Black Holes and Single Millisecond Pulsars in Globular Clusters
Authors: Kremer Kyle , Ye Claire S. , Kıroğlu Fulya , Lombardi James C. , Ransom Scott M. , Rasio Frederic A. 
Published: July 2022

Abstract
Close encounters between neutron stars and main-sequence stars occur in globular clusters and may lead to various outcomes. Here we study encounters resulting in the tidal disruption of the star. Using N-body models, we predict the typical stellar masses in these disruptions and the dependence of the event rate on the host cluster properties. We find that tidal disruption events occur most frequently in core-collapsed globular clusters and that roughly 25% of the disrupted stars are merger products (i.e., blue straggler stars). Using hydrodynamic simulations, we model the tidal disruptions themselves (over timescales of days) to determine the mass bound to the neutron star and the properties of the accretion disks formed. In general, we find roughly 80%–90% of the initial stellar mass becomes bound to the neutron star following disruption. Additionally, we find that neutron stars receive impulsive kicks of up to about 20 km s−1 as a result of the asymmetry of unbound ejecta; these kicks place these neutron stars on elongated orbits within their host cluster, with apocenter distances well outside the cluster core. Finally, we model the evolution of the (hypercritical) accretion disks on longer timescales (days to years after disruption) to estimate the accretion rate onto the neutron stars and accompanying spin-up. As long as ≳1% of the bound mass accretes onto the neutron star, millisecond spin periods can be attained. We argue the growing numbers of isolated millisecond pulsars observed in globular clusters may have formed, at least in part, through this mechanism. In the case of significant mass growth, some of these neutron stars may collapse to form low-mass (≲3 M
⊙) black holes.
L’intelligence artificielle au service du monde des fusions acquisitions : la plateforme Sealk
Authors: Pouzenc Gilles 
Published: July 2022

L’émergence des startups dans les économies mondiales et l’arrivée massive des fonds d’investissement ont bousculé le monde des affaires depuis les années 2000, posant le problème de l’information d’une manière aiguë. Dans ce monde prolifique et bouillonnant, le réseau personnel et les bases de données manuelles ne suffisent plus : les nouvelles technologies, en particulier l’intelligence artificielle, viennent révolutionner la recherche de cibles dans une stratégie d’acquisition d’entreprises (M&A). Ainsi, la plateforme Sealk (en phase de pré-commercialisation), utilise l’IA pour collecter des informations récentes et pertinentes sur les startups ou les PME/PMI, mais aussi de manière prédictive : à partir de l’analyse des opérations de fusion ou d’acquisition, tel grand groupe peut anticiper - prévoir quelle start-up acquérir s’il veut ne pas prendre de retard sur ses concurrents ; inversement, une start-up peut chercher à quels grands groupes s’adosser. Cette solution puissante et originale, destinée aux banquiers d’affaires, aux fonds d’investissement et aux grands groupes, ne requiert aucune connaissance en programmation.
L’intelligence artificielle au défi du multilinguisme : usages et perspectives de la traduction automatique neuronale dans la communication scientifique
Authors: Fiorini Susanna 
Published: July 2022

Au vu des récentes avancées en termes de performances et accessibilité, la traduction automatique neuronale apparaît comme la solution pour briser les barrières linguistiques freinant la circulation de l’information et des savoirs. Son rôle deviendrait donc déterminant dans un paysage à dominante anglophone comme la communication scientifique, qui pourrait ainsi se projeter vers un multilinguisme systématique. Les études réalisées jusqu’à aujourd’hui montrent cependant une réalité plus nuancée, qui fait certes ressortir les bénéfices de ces outils, mais également leurs limites : exploitation opaque des données des utilisateurs, biais et effet « boîte noire », contraintes linguistiques, textuelles et disciplinaires, usages peu éclairés, méconnaissance du paysage des technologies disponibles. Dans ce contexte, les réflexions sur les usages et perspectives de la traduction automatique dans la communication scientifique trouvent tout leur sens et montrent la nécessité de mettre en place des solutions ad hoc afin que ces technologies puissent réellement répondre aux besoins des communautés scientifiques.
Entre gueuserie et bas-fonds, une mutation inédite des représentations du crime organisé : l’image de la bande dans l’ Histoire de la vie et du procès de Cartouche (1722)
Authors: Peveri Patrice 
Published: July 2022

L’étude se propose de présenter et d’analyser la description de la bande de Cartouche fournie par l’ Histoire de la vie et du procès de Louis Dominique Cartouche et de ses complices , ouvrage de colportage publié en 1722 au lendemain de l’exécution du bandit. Méconnue, cette représentation des milieux criminels fut conçue comme un instrument de propagande destiné à contrecarrer l’aura positive dont bénéficia Cartouche auprès d’une part importante de la société parisienne. Si elle reprend quelques éléments d’une littérature de la gueuserie déjà ancienne et frappée d’obsolescence, elle comporte de nombreuses innovations qu’il faut envisager non pas comme des reflets des réalités des réseaux criminels mais comme un imaginaire constitué à dessein pour faire résonner chez les lecteurs des craintes nourries par les évolutions récentes qui marquèrent la société urbaine. Cette représentation ne parvint cependant pas à s’imposer durablement, à l’instar de l’imaginaire des bas-fonds au xix e siècle, et à structurer le regard porté sur les marges de la société. Conçue pour justifier une entreprise d’éradication à grande échelle de l’économie parisienne du vol des années 1720, elle ne résista ni aux mutations de la criminalité et des pratiques répressives qui marquent la seconde moitié du xviii e siècle, ni à l’usure d’un ouvrage visant à la désinformation.
La ligne ferroviaire Nîmes-Alès : premier bilan d’un contrat d’axe original
Authors: Haro Florent , Duvic Nicolas 
Published: July 2022

Cet article dresse un premier bilan du renforcement de la ligne ferroviaire Nîmes-Alès, qui a débouché sur une nette augmentation de la fréquentation. Cette évolution constituait le premier jalon d’un contrat d’axe ambitieux établi dans un contexte institutionnel complexe avec 6 intercommunalités parties prenantes. Sur la base de cette première expérience, les auteurs tracent des perspectives pour une nouvelle génération de contrats d’axes.
Les supermarchés au Mexique et dans la Zone Métropolitaine de Mexico
Authors: Capron Guénola , González Arellano Salomón , Moreno Sánchez Linda 
Published: July 2022

L’article analyse les logiques d’expansion et de distribution spatiale des supermarchés à trois échelles : planétaire, nationale (Mexique), et surtout, métropolitaine (Mexico), des espaces et catégories sociales riches vers les pauvres. Il cherche à comprendre comment les supermarchés, dans un pays comme le Mexique où ils ciblent au départ principalement la classe moyenne, reproduisent ou atténuent les disparités socio-spatiales. Nous concluons qu’ils sont un facteur à la fois d’atténuation (du fait d’une relativement bonne distribution dans l’espace métropolitain) et de reproduction des inégalités (en raison de la segmentation de l’offre). Dans le cas de la métropole de Mexico, la situation d’oligopole par l’entreprise Wal-Mart constitue un risque par rapport à la souveraineté et la sécurité alimentaires de la ville.
Recent Trend in the Antimicrobial Resistance Pattern of Urinary Pathogens in a Tertiary Care Hospital
Authors: Astha  , Singh Ravinder Pal 
Published: July 2022

Introduction:
Antibiotic resistance is a worldwide problem. Organisms are developing resistance not only to commonly used antibiotics but also to high end and less commonly used antibiotics.

Aim:
The present study has been designed to find out the recent trend of antibiotic resistance profile of uropathogens as urinary tract infection is one of the commonest infections among outdoor and indoor patients. This will help clinicians to select most appropriate antibiotics to treat their patients empirically. This will also help in not only preventing the development but also reducing the spread of antibiotic resistance.

Material and Methods:
The study was conducted in the Microbiology Department, F.H. Medical College, Etmadpur, Agra, India, from March 2019 to August 2019. Mid-stream urine samples were collected from patients and transported within an hour and were inoculated on blood agar and MacConkey agar. After incubation at 37°C for 24 h, organisms were identified and sensitivity test was done by Kirby Bauer's disc diffusion method using Mueller Hinton Agar.

Results:
Members of the Enterobacteriaceae family showed resistance to almost all groups of antibiotics except piperacillin-tazobactam, imipenem, and nitrofurantoin while gram-positive organisms were found to be sensitive only to vancomycin, teicoplanin, linezolid, and nitrofurantoin. Situation with nonfermenters (Pseudomonas aeruginosa and Acinetobacter spp.) was alarming as they were found resistant to ceftazidime, cefepime, piperacillin, gentamicin and ciprofloxacin, and also significant resistance with imipenem was seen. Only colistin, polymyxin B and piperacillin-tazobactam showed satisfactory results and could be considered for use in empirical treatment.

Conclusion:
Present study shows how serious the problem of increasing antibiotic resistance is and emphasizes the need of continuous surveillance of antibiotic susceptibility of uropathogens that will help to formulate an effective antibiotic policy to guide the clinicians.