bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH LAMA WAKTU PENGGARAMAN YANG BERBEDA TERHADAP KADAR LEMAK DAN PROFIL ASAM LEMAK CUMI-CUMI (Loligo feakii)
Authors: Puspitasari Findya , Aidawati Noor , Rina Rina , Adawyah Rabiatul 
Published: August 2022

Cumi-cumi adalah binatang yang mempunyai tubuh lunak dan berbentuk silindris sedangkan siripnya berbentuk trianguler. Pada bagian kepala dekat mulut terdapat 10 tentakel serta dilengkapi alat penghisap dan pada bagian tubuh cumi-cumi memiliki sumber asam lemak hewani dimana komponen penyusun lemak. Tujuan dari penelitian yaitu untuk mengetahui pengaruh lama waktu penggaraman yang berbeda terhadap profil asam lemak cumi-cumi. Rancangan penelitian yang digunakan yaitu rancangan acak lengkap (RAL) dengan menggunakan 4 perlakuan lama waktu yang berbeda terhadap lemak dan profil asam lemak cumi-cumi (Loligo fiealii). Hasil penelitian menyatakan bahwa kandungan lemak tidak berbeda nyata dan asam lemak cumi-cumi (Loligo fiealii) terdapat 30 jenis asam lemak dengan asam tertinggi yaitu asam stearat sebesar 3,40% pada perlakuan O (cumi segar) di golongan asam lemak jenuh (SFA), sedangkan golongan asam lemak tak jenuh tunggal (MUFA) yang tertinggi yaitu asam cis-10-pentadekanoat sebesar 11,30% pada perlakuan C (5 hari) dan asam lemak tak jenuh jamak (PUFA) tertinggi terdapat pada asam cis-4,7,10,13,16,19-dokosaheksanoat sebesar 11,10% pada perlakuan C (5 hari).
The squid is an animal that has a soft and cylindrical body while its fins are triangular. On the head near the mouth there are 10 tentacles and equipped with a suction device and on the body part of the squid has a source of animal fatty acids, which are the constituent components of fat. The aim of this study was to determine the effect of different salting times on the fatty acid profile of squid. The research design used was a completely randomized design (CRD) using 4 different treatments of time to the fatty acid profile of squid (Loligo fiealii). The results showed that the fatty acids of squid (Loligo fiealii) Contained 30 types of fatty acids with the highest acid, namely stearic acid at 3.40% in treatment O (fresh squid) in the saturated fatty acid (SFA) group, while the highest monounsaturated fatty acid (MUFA) was cis-10-pentadecanoic acid at 11.30% in C treatment (5 days) and the highest polyunsaturated fatty acid (PUFA) was cis-4,7. 10,13,16,19-docosahexanoate 11,10% in treatment C (5 days)
SUPLEMENTASI Artemia sp DAN Daphnia sp UNTUK PERTUMBUHAN DAN SINTASAN LARVA IKAN PAPUYU (Anabas testudineus)
Authors: Alfian Muhammad , Herliwati Herliwati , Olga Olga 
Published: August 2022

Penelitian ini bertujuan untuk mengkaji pertumbuhan dan sintasan larva ikan papuyu (Anabas testudineus Bloch) dengan pemberian Artemia sp dan Daphnia sp bersuplemen Viterna dan mengetahui pakan alami bersuplemen terbaik untuk dijadikan pakan larva papuyu. Larva ikan papuyu dipelihara selama 34 hari. Rancangan yang digunakan pada penelitian ini adalah rancangan acak lengkap (RAL) dengan 4 perlakuan dan 3 ulangan. Perlakuan yang digunakan antara lain A (Daphnia sp non suplemen), B (Artemia sp non suplemen), C (Daphnia sp bersuplemen), D (Artemia sp bersuplemen). Hasil penelitian ini menunjukkan bahwa pemberian Artemia sp dan Daphnia sp bersuplemen berpengaruh nyata terhadap pertumbuhan panjang dan berat relatif, dan sintasan larva papuyu. Perlakuan terbaik untuk panjang relatif, yakni C (266,67%) yang diikuti D (254,94%), berat relatif pada perlakuan D (187,78%) dan sintasan pada perlakuan D (77%) dan C (70%). Sedangkan kualitas air media pemeliharaan, yakni suhu 25 -27,4 oC, DO 2,01-3,10 mg/L, pH 6,3 – 7,9, dan amoniak (NH3) 0,15 – 0,26 mg/L masih dalam kisaran yang baik untuk kehidupan papuyu.
This study aimed to study the growth and survival of climbing perch (Anabas testudineus Bloch) larvae with Artemia sp and Daphnia sp supplemented with Viterna and to find out the best natural food supplemented to be used as feed for climbing perch larvae. Climbing perch fish larvae were reared for 34 days. The design used in this study was a completely randomized design (CRD) with 4 treatments and 3 replications. The treatments used included A (Daphnia sp non-supplemented), B (Artemia sp non-supplemented), C (Daphnia sp supplemented), D (Artemia sp supplemented). The results of this study showed that the supplementation of Artemia sp and Daphnia sp had a significant effect on the growth of relative length and weight, and the survival of climbing perch larvae. The best treatment for relative length, namely C (266.67%) followed by D (254.94%), relative weight in treatment D (187.78%) and survival in treatment D (77%) and C (70%) . While the water quality of the maintenance media, namely the temperature 25 -27.4 oC, DO 2.01-3.10 mg/L, pH 6.3 - 7.9, and ammonia (NH3) 0.15 - 0.26 mg/L is still in a good range for climbing perch's life.
PENGARUH PENAMBAHAN EKSTRAK DAUN KELOR (Moringa oleifera) TERHADAP PENERIMAAN PANELIS DAN KANDUNGAN ASAM AMINO KERUPUK IKAN GABUS (Channa striata)
Authors: Suhanda Juhana , Baharuddin Baharuddin , Wichaldinoor M Khair , Noormaliani Herni , Adawyah Rabiatul 
Published: August 2022

Kerupuk ikan adalah jenis jajanan yang populer di Indonesia khususnya Kalimantan Selatan. Bahan kerupuk ikan gabus yang dicampur dengan ekstrak daun kelor adalah inovasi baru dalam mengolah bahan makanan dan menambah sumber protein hewani. Komponen utama pada protein adalah asam amino. Tujuannya untuk mengetahui kadar air dan kandungan asam amino pada kerupuk ikan gabus dengan penambahan ekstrak daun kelor. Rancangan yang digunakan adalah RAL dengan 4 perlakuan dan 4 kali ulangan yaitu perlakuan O (tanpa penambahan ekstrak dun kelor), A (10 ml), B (20 ml), dan C (30 ml). Hasil dari keempat perlakuan menunjukkan bahwa penambahan ekstrak daun kelor pada kerupuk ikan gabus pada penerimaan panelis tidak mempengaruhi terhadap kenampakan aroma juga rasanya tetapi penambahan ekstrak 30 ml lebih disukai panalis untuk kenampakan dan rasanya, tekstur kerupuk ikan gabus jika ditambahkan di atas 20 ml menurunkan nilai penerimaan panelis. Pemberian ekstrak daun kelor berpengaruh terhadap pola asam aminonya dimana untuk Asam Amino esensial yang tertinggi adalah lisin dan yang non esenseal adalah asam glutamat.

Fish crackers are one of the most popular types of snacks in Indonesia, especially in South Kalimantan. Cork fish cracker material mixed with Moringa leaf extract is the latest innovation in the manufacture of food ingredients and can add sources of animal protein. The main components of protein are amino acids. This study aims to determine the water content and amino acid content in snakehead fish crackers with the addition of Moringa leaf extract. The method used in this study was RAL with 4 treatments and 4 repetitions, namely design O (without the addition of dun Moringa extract), A (10 ml), B (20 ml), and C (30 ml). The results of the four treatments showedthat the addition of Moringa leaf extract to snakehead fish crackers at the reception of the panelists did not affect the appearance of the aroma as well as the taste but the addition of an extract of 30 ml was preferred panalis for the appearance and taste, the texture of snakehead fish crackers if added above 20 ml lowered the value of the panelist's acceptance. The administration of Moringa leaf extract affects the amino acid pattern where for the highest essential amino acid is lysine and the non-esenseal one is glutamic acid.
PENGARUH PERBANDINGAN DAGING IKAN DENGAN TEPUNG TAPIOKA YANG BERBEDA TERHADAP KUALITAS KERUPUK IKAN GABUS (Channa striata)
Authors: Purnomo Purnomo , Soetikno Nooryantini , Windari Wiwin , Adawyah Rabiatul 
Published: August 2022

Ikan gabus (Channa striata) merupakan ikan air tawar yang memiliki sifat fungsional yaitu memiliki protein cukup tinggi, dapat mempercepat penyembuhan luka dan mempunyai efek antiezing. Kerupuk ikan adalah salah satu produk diversifikasi olahan yang bahan utamanya ditambahkan daging ikan selain tepung tapioka.Tujuan dari penelitian ini adalah untuk mendapatkan hasil yang optial dari perbandingan daging ikan dengan tepung tapioka yang berbeda terhadap kualitas kerupuk ikan gabus.Penelitian ini menggunakan tiga perlakuan yaitu perbandingan daging ikan dengan tepung tapioka (1:3, 1:2, 1:1) dan uji yang dilakukan meliputi uji organoleptik, fisik dan kimia.
Hasil penelitian uji organoleptik menunjukkan bahwa nilai perlakuan yang terbaik dengan penambahan daging ikan dengan tepung tapioka 1:3 karena perlakuan tersebut paling disukai oleh panelis dan memiliki hasil perbandingan yang optimal terhadap kualitas kerupuk ikan gabus yang ditinjau dari segi kenampakan, warna, aroma, tekstur dan rasa. Sehingga perbandingan daging ikan dengan tepung tapioka yang berbeda berpengaruh nyata terhadap kualitas kerupuk ikan gabus.
circ_0052184 promotes colorectal cancer progression via targeting miR-604/HOXA9 axis
Authors: Huang Yandong , Bai Qinyang , Wang Zhanlong , Yu Hongbo , Li Yanru , Lu Hao , Kang Huimin , Shi Xuewei , Feng Kai 
Published: August 2022

Abstract
Background:The mortality rate of colorectal cancer (CRC) ranks second. CircRNAs are abnormal expression in some diseases, and their dysregulation is associated with cancer progression. Recent studies have shown that the malignant progression of colorectal cancer is inseparable from the abnormal expression of circRNAs.Methods:First, the circ_0052184 expression in clinical tissue and cell samples was analyzed by qRT-PCR. Then, we constructed circ_0052184-silenced CRC cells and detected by qRT-PCR. Furthermore, the proliferation ability of cells was detected by colony formation assay. Cell migration ability was tested by wound healing assay and transwell assay. Cell invasion ability were detected by transwell assay.Results:Expression of circ_0052184 was significantly increased in colorectal cancer cell lines and tissues. Silencing circ_0052184 affected the proliferation, migration and invasion of colorectal cancer cells. MiR-604 was targeted by circ_0052184. The downstream target of miR-604 was HOXA9, and silencing circ_0052184 inhibited HOXA9 expression. The existence of circ_0052184/miR-604/HOXA9 regulatory network in colorectal cancer was validated. Circ_0052184 promoted the occurrence and development of colorectal cancer by targeting the miR-604/HOXA9 axis.Conclusions:Our study revealed that the molecular mechanism of circ_0052184 regulated the miR-604/HOXA9 axis, which might promote the malignant progression of colorectal cancer cells.
Potential Antibacterial Co-culture first-reported Streptomyces flavalbus from Indonesian mangroves induces the production of pyocyanin by Pseudomonas aeruginosa
Authors: Azhar Nuril , Yudiati Ervia 
Published: August 2022

Abstract
The potential Actinobacteria from the sediment and root Soneratia alba with co-culture as an antibacterial agent. Out of 580 fermentation, 540 fermenter co-cultures and 34 single fermenter cultures were assessed. Twenty-one pairs of co-culture were resulted positively against Staphylococcus aureus, and 16 pairs were positive against Pseudomonas aeruginosa. The highest clearance zone against S. aureus was obtained from 10 (Actino)-Aspergillus fumigatus (dead body) extract (21.57±0.90 mm) while against P. aeruginosa was resulted from co-culture strains 3/37 extract (19.18±0.80 mm). Strain 41 was determined to be Streptomyces flavalbus (98.07%) with the accession number MZ540332 when co-cultured with Pseudomonas aeruginosa to produce pyocyanin. This is the first report of Streptomyces flavalbus, a novel species from mangrove sediments, and the second one from natural habitat. It is concluded that co-culture is a valuable strategy to develop the new Actinobacteria product as a powerful antibacterial agent.
Anomaly detection at the subnetwork level: traffic classification for machine learning algorithms
Authors: Rivas Lucia , Leira Rafael , Aracil Javier 
Published: August 2022

Abstract
In this paper we propose a traffic classification methodology for subnetwork level anomaly detection using machine learning algorithms. Our proposed techniques allow researchers and practitioners in the field to classify the corresponding traffic multiplex constituents (subnetworks) according to their predictability level beforehand. Subnetworks deemed as predictable yield smaller prediction error than the rest, under well-known machine learning prediction algorithms, such as ANN, GRU and LSTM. Thus, such predictability features makes the former better suited for anomaly detection purposes, that are based on deviations from predicted values, while the rest are prone to produce false positives.
Evaluation of CT Imaging Protocol for Suspected Acute Aortic Syndrome in the Emergency Department Setting
Authors: Goh Xin Lyn , Seah Sebastian , Duong Peter , Mong Lisa , Rotella Joe-Anthony , Lim Ruth 
Published: August 2022

Abstract
Background: Acute aortic syndromes (AAS) are highly fatal cardiovascular emergencies. Rapid and accurate diagnosis is essential to improve survival due to their high mortality rate. Thoracic AAS can extend distally into the abdominal aorta and iliac arteries; therefore, simultaneous imaging of the abdomen and pelvis is often performed to identify concomitant mesenteric or abdominal visceral malperfusion. However, there is a paucity in the literature regarding incidence of extra-thoracic extension with AAS. Use of large coverage CT in a low-prevalence population may result in unnecessary radiation, and increase false-positives due to artefacts mimicking aortic dissection. The primary objective of the study was to evaluate the positive rate of diagnosis and of extra-thoracic extension of AAS in patients presenting to a tertiary teaching hospital Emergency Department with suspected AAS. A secondary objective was to evaluate impact of a standardized CT imaging protocol for AAS on radiation dose.Methods: Retrospective single-center cohort study of Emergency Department patients undergoing CT for suspected AAS over two one-year periods, comparing a baseline study period (no standardized protocol) to a post-standardization imaging protocol period. Positivity rate and extent of AAS, and radiation dose for studies were recorded and compared with the χ2 test, paired t-test and Mann-Whitney U test. Additional positive cases where AAS was not suspected were also recorded.Results: 228 and 266 patients were investigated during baseline and post-standardization periods respectively. Of the total 494 patients, there were 13 (2.6%) cases of AAS; 6/13 with extra-thoracic extension, of which 5/6 presentation CTs included abdominopelvic imaging for extrathoracic symptoms/signs. Post-standardization, the standardized protocol was used in 78.3% of examinations versus 53.7% at baseline (p <0.001) with a decreased median effective dose per study (9.1 to 8.4 mSv, p=0.049). Median effective dose of the standardized protocol was 8.0 mSv and compared to 13.9 mSv for NC and CTA of the chest, abdomen and pelvis was (p <0.001). Conclusions: The overall positivity rate of AAS was low. In the absence of extrathoracic signs/symptoms, a standardized CT protocol for investigation of AAS omitting abdominopelvic imaging during initial work up could save approximately 6 mSv of radiation dose per study.
Co-Cultivation of Human Granulosa Cells with Ovarian Cancer Cells Leads to a Significant Increase in Progesterone Production
Authors: Pietrowski Detlef , Grgic Martina , Haslinger Isabella , Marschalek Julian , Schneeberger Christian 
Published: August 2022

Abstract
In humans, granulosa cells (GCs) are part of the follicle and nourish the growing oocyte. GCs produce oestrogen and, after ovulation, progesterone. They are embedded in a multicellular tissue structure of the ovary, which consists of a variety of different cell types that are essential for the physiological function of the ovary. However, the extent to which individual ovarian cell types contribute to overall functionality has not yet been fully elucidated. In this study, we aim to investigate the effects of co-culturing human granulosa cells with ovarian cancer cells on their progesterone and oestrogen production in an in vitro model. After seeding, the cells were stimulated with 200µM forskolin in DMEM for 72 hours and the medium of the different cell culture experiments was collected. Subsequently, progesterone and oestradiol concentrations were determined using an Elisa assay. Morphologically, it was striking that the cells self-organise and form spatially separated areas. Compared to culturing granulosa cells alone, co-culturing human granulosa cells together with the ovarian cancer cell line OvCar-3 resulted in a significant increase in progesterone production (20.3ng/ml versus 50.2ng/ml; p < 0.01). Using a simple in vitro model, we highlight the importance of cellular crosstalk between different ovarian cells in a complex cellular network and that it strongly influences granulosa cell hormone production. This could have potential implications for the procedure of transplanting endocrine tissues after cryopreservation, as it highlights the importance of survival of all cells for the functionality of the transplanted tissue.
Evaluation of impact of continuous KMC initiated immediately after birth compared to KMC initiated after stabilization, in newborns with birth weight 1.0 to &lt;1.8 kg on neurodevelopmental outcomes: protocol for a follow-up study
Authors: Adejuyigbe EA , Agyeman I , Anand P , Anyabolu HC , Arya S , Assenga EN , Badhal S , Brobby NW , Chellani HK , Chopra N , Debata PK , Dube Q , Dua T , Gadama L , Gera R , Hammond CK , Jain S , Kantumbiza F , Kawaza K , Kija EN , Lal P , Mallewa M , Manu MK , Mehta A , Mhango T , Naburi HE , Newton S , Nyanor I , Nyarko PA , Oke OJ , Patel A , Phlange-Rhule G , Sehgal R , Singhal R , Wadhwa N , Yiadom AB 
Published: August 2022

Abstract
Background:Preterm birth or low birth weight is the single largest cause of death in newborns, but the mortality can be reduced through newborn care interventions, including Kangaroo Mother Care (KMC). Previously, a multi-country randomized controlled trial, coordinated by the World Health Organization reported a significant survival advantage with initiation of continuous KMC immediately after birth compared with initiation of continuous KMC a few days after birth when the baby is considered clinically stable.Whether the survival advantage would lead to higher rates of neurodevelopmental morbidity, or the immediate KMC will have a beneficial effect on cognitive development also, has not been investigated. We therefore propose to test the hypothesis that low-birth-weight infants exposed to immediate KMC will have lower rates of neurodevelopmental impairment in comparison to traditional KMC-treated infants, by prospectively following up infants already enrolled in the immediate KMC trial, for the first two years of life, and assessing their growth and neurodevelopment. Methods:This prospective cohort study will enroll surviving neonates from the main immediate KMC trial. The main trial as well as this follow-up study are being conducted in five low- and middle-income income countries in South Asia and sub-Saharan Africa. The sample size for comparison of risk of neurodevelopmental impairment is a total of about 2200 neonates. The primary outcomes will include rates of cerebral palsy, hearing impairment, vision impairment, mental and motor development, and epilepsy and will be assessed by the age of three years. The analysis will be by intention to treat.DiscussionImmediate KMC can potentially reduce low-birth-weight associated complications such as respiratory disease, hypothermia, hypoglycemia and infection that can result in impaired neurocognitive development. Neuroprotection may also be mediated by improved physiological stabilization that may lead to better maturation of neural pathways, reduced risk of hypoxia, positive parental impact, improved sleep cycles and improved stress responses. The present study will, therefore, help in evaluating the overall impact of KMC by investigating the long-term effect on neurodevelopmental impairment in the survivors.Trial registrationClinical Trials Registry-India: CTRI/2019/11/021899 on 06 November 2019
Seismic fragility assessment of steel moment-resisting frames equipped with superelastic viscous dampers
Authors: ghasemi abbas , Arkavazi Fatemeh , Shakib Hamzeh 
Published: August 2022

Abstract
The superelastic viscous damper (SVD) is a hybrid passive control device comprising a viscoelastic damper and shape memory alloy (SMA) cables connected in series. The SVD is an innovative damper through which a large amount of seismic energy can dissipate. The current study assessed the seismic collapse induced by steel momentresisting frames (SMRFs) equipped with SVDs and compared them with the performance of special MRFs and buckling restrained brace frames (BRBFs). For this purpose, nonlinear dynamic and incremental dynamic analysis (IDA) were conducted in OpenSees software. Both 5- and 9-story special MRFs, BRBFs, and MRFs equipped with the SVDs were examined. The results indicated that the annual exceedance rate for maximum residual drifts of 0.2% and 0.5% for the BRBFs and MRFs with SVDs, respectively, were considerably less than for SMRFs with reduced-beam section (RBS) connections and that the seismic performances of these structures were enhanced with the use of the BRB and SVD. The probability of collapse due to residual drift in the SVD, BRB, and RBS frames in the 9-story structure was 1.45, 1.75, and 1.05 times greater than for the 5-story frame.
Psychopathology and Eating Behaviour in People with Type 2 Diabetes Referred to Bariatric Surgery
Authors: Pekin Clare , McHale Mala , Seymour Matthew , Strodl Esben , Hopkins George , Mitchell David , Byrne Gerard 
Published: August 2022

Abstract
Purpose
Psychopathology and disordered eating behaviours are putative pre-operative risk factors for suboptimal post-operative outcomes among people seeking bariatric surgery. Studies vary in the prevalence rates reported for psychopathology in bariatric candidates. Further, less attention has been paid to vulnerable subgroups such as people with diabetes who might be at an elevated risk. For these reasons this study aimed to investigate the rates of psychopathology and disordered eating in pre-surgical candidates with Type 2 Diabetes Mellitus (T2DM).
Methods
Participants were 401 consecutive patients from a statewide bariatric surgery service for people with T2DM comparing indigenous and non-indigenous Australians. Psychopathology was measured using multi-modal assessment (e.g. diagnostic interview and battery of validated questionnaires). The mean age of the sample was 51 years (18–65 years) with a mean body mass index (BMI) of 46 (30.5–69.3). The majority of the sample was female (60.6%) and born in Australia (87%), and 19.2% identified as Aboriginal and/or Torres Strait Islander.
Results
High prevalence rates of depression, history of attempted suicide, generalised anxiety, emotional eating and post-traumatic stress disorder were found in this sample in comparison to reference groups. There were no significant differences between those who identified as Aboriginal and/or Torres Strait Islander and those who did not.
Conclusion
Our cross-sectional findings indicate psychopathology is common in this population. Longitudinal designs in future studies could provide important insights into how psychopathology and disordered eating relate to post-bariatric surgical outcomes for people with T2DM. Further research is warranted to explore mood, anxiety, emotional eating and alcohol use post-operatively.