bluuebunny/crossref_metadata_2025_split huggingface dataset:
ОСОБЕННОСТИ ДИАБЕТИЧЕСКОЙ МАКУЛОПАТИИ У БОЛЬНЫХ САХАРНЫМ ДИАБЕТОМ 2-го ТИПА
Authors: Mogilevskyy S. Yu. , Panchenko Yu. O. 
Published: January 2022

В статье приведены результаты исследования особенностей диабетической макулопатии убольных (361 глаз) сахарным диабетом 2-го типа. Установлено, что частота диабетическоймакулопатии составила 72,6%, диабетического макулярного отёка – 46,0%. Их частота неотличалась ни при умеренной и тяжёлой непролиферативной диабетической ретинопатии,ни при пролиферативной диабетической ретинопатии. Частота диабетической макулопатиизависела от продолжительности диабета, в то же время от диабетического макулярного отёка не зависела. Установлено, что их частота была статистически значимо ниже в группе 51–60 лет и не отличалась в группах до 40 лет, 41–50 лет, 61–70 лет, 71 год и старше.
ОКЛЮЗІЇ СУДИН СІТКІВКИ ПІСЛЯ КАРДІОХІРУРГІЧНИХ ВТРУЧАНЬ ІЗ ВИКОРИСТАННЯМ ШТУЧНОГО КРОВООБІГУ
Authors: Rykov S. O. , Venediktova O. A. 
Published: January 2022

Значною групою ризику виникнення оклюзій судин сітківки є пацієнти з серцево-судинними захворюваннями. Сьогодні лікування хворих з вродженими та набутими вадами серця, ішемічною хворобою серця (ІХС) неможливе без хірургічних втручань, більшість яких потребує використання штучного кровообігу (ШК). Під час операції ШК внаслідок тривалої гіпотермії, гемодилюції, пролонгованої гіпотензії та анемії можливий розвиток офтальмологічних ускладнень у ранньому післяопераційному періоді. Нами було проведене офтальмологічне обстеження 220 пацієнтів із різноманітною патологією судин серця та клапанів, яким проводилося кардіохірургічне втручання з використанням ШК, з метою дослідження характеру, частоти, особливостей розвитку та клінічного перебігу оклюзій судин сітківки. В результаті в ранньому терміні спостереження виявлені такі оклюзії судин сітківки: оклюзія центральної вени сітківки – 4 ока (0,99%), оклюзія гілок ЦВС – 15 очей (3,7%), геміцентральна ретинальна оклюзія – 1 око (0,24%), оклюзія центральної артерії сітківки – 1 око (0,24%).Сумарний відсоток оклюзії судин сітківки за перший тиждень спостережень у пацієнтів після кардіохірургічних операцій з ШК склав 5,18% (21 око). А також, окрім оклюзій судин сітківки, були виявлені геморагічні ускладнення у вигляді часткового гемофтальма, поодиноких інтраретинальних геморагій, периферичних крововиливів, передретинальних крововиливів, гіфеми, субкон’юнктивальних крововиливів, сумарний відсоток яких склав 18,44% (71 око).
СОСТОЯНИЕ АНТИОКСИДАНТНОЙ СИСТЕМЫ В НЕЙРОНАЛЬНЫХ ТКАНЯХ ГЛАЗА ПРИ МОДЕЛИРОВАНИИ ОФТАЛЬМОГИПЕРТЕНЗИИ У ЖИВОТНЫХ СО СТРЕПТОЗОТОЦИНОВЫМ ДИАБЕТОМ
Authors: Yurevych V. R. 
Published: January 2022

Поиск лекарственных препаратов, направленных на нормализацию обменных процессов в тканях глаза при сахарном диабете и офтальмогипертензии, является крайне актуальным. При этом эффективность лекарственной терапии определяется ее патогенетической направленностью.Поэтому уточнение вопросов патогенеза этих патологий остается по-прежнему важным.Цель исследования – изучение состояния ферментативной антиоксидантной системы в нервных тканях глаза при моделировании офтальмогипертензии у животных со стрептозотоциновым диабетом.Материалы и методы. Исследования проводились на 32 кроликах. Подопытные животные были разделены на четыре группы: 1-ая – контрольная группа (8 кроликов); 2-ая – опытная группа, животные с диабетом в условиях гипертензии (10 кроликов); 3-я – опытная группа, животные с диабетом (7 кроликов); 4-ая – опытная группа, животные с гипертензией (7 кроликов). В тканях изолированной сетчатки и зрительного нерва производили определение активности каталазы, супероксиддисмутазы и глутатионпероксидазы.Результаты и их обсуждение. Анализируя полученные нами результаты по изучению активности ферментов антиоксидантной системы в нервных тканях глаза при моделировании гипертензии у животных со стрептозотоциновым диабетом, необходимо отметить значительное снижение потенциала системы обезвреживания активных форм кислорода.Выводы. 1. Выявлено, что развитие офтальмогипертензии у животных с сахарным диабетом приводит к более выраженному снижению потенциала системы обезвреживания активных форм кислорода в тканях глаза по сравнению с диабетом и гипертензией у отдельных групп животных. Активность супероксиддисмутазы и каталазы в сетчатке и зрительном нерве при сочетанном развитии сахарного диабета и гипертензии была значимо ниже по сравнению с диабетическими условиями на 16,5% и 17,9% соответственно.2. Установлено, что при совместном протекании глазной гипертензии и гипергликемии скорость обезвреживания липидных гидропероксидов в нервных элементах зрительного анализатора была значительно снижена по сравнению с нормой и животными с гипертензией. Активность глутатионпероксидазы была снижена в этих условиях на 43,2% и 32,8% соответственно.
Studi Eksperimen Pengaruh Sudut Pitch terhadap Karakteristik Performa pada Turbin Angin Counter-Rotating
Authors: Azhar Faruq Avero , Bramantya Muhammad Agung 
Published: January 2022

Pemanfaatan energi angin menjadi daya berguna menuntut peningkatan efisiensi turbin angin. Cara lain untuk meningkatkan efisiensi dengan menggunakan turbin angin counter-rotating. Pada penelitian ini dilakukan pengamatan performa dari turbin angin full Scale model counter-rotating (CRWT) dengan sebuah generator dan roda gigi. Pengujian dilakukan pada kondisi lingkungan sebenarnya dan kecepatan angin yang fluktuatif. Rotor turbin depan dan belakang menggunakan 3 buah bilah dengan rasio diameter (D1/D2) = 0,5. Desain aerodinamika bilah turbin counter-rotating dibuat berdasarkan perhitungan menggunakan teori Blade Element Momentum (BEM). Sudut pitch rotor turbin diatur sebesar 0°, 10° dan 20° dan diamati daya elektrik keluaran dari generator untuk mengetahui perbedaan performa dari masing-masing variasi. Koefisien daya maksimum yang dihasilkan oleh rotor pada kecepatan angin 4 m/s sampai 7 m/s dengan sudut pitch 0° sebesar . Sedangkan turbin angin dengan sudut pitch rotor 10° dan 20° koefisien daya tertinggi masing-masing tercapai sebesar dan . Hasil pengujian menunjukkan semakin besar sudut pitch koefisien daya yang dihasilkan pada kecepatan angin rendah semakin besar, akan tetapi semakin tinggi kecepatan angin rotor dengan sudut pitch kecil menghasilkan koefisien daya yang lebih besar.
Branching angles of several cocoa genotypes and their effect on determining optimum plant spacing
Authors: Setyawan Bayu , Anita-Sari Indah , Ihsan Fatrezza , Panua Heksan 
Published: January 2022

Identification of the type of branching architecture will be one for the considerations in determining specific spacing recommendations for cocoa plantation. The research was conducted at Kaliwining Experimental Station, Indonesian Coffee and Cocoa Research Institute. The aim of this study was to investigate of branching angle characteristics of cocoa clones that can be used in determining planting space in cocoa farms. This research usied a completely randomized block design (RCBD) consisting of 21 genotypes as treatments. Each treatment was repeated three times and each replication consisted of three sample plants. Parametersobserved were branch angle and the type of branching. Branch angle is the angle formed by the outermost primary branch and was measured using a protractor. The results showed that each genotype had a different angle on the primary branch, while the secondary and tertiary branch angles did not shown any significantdifference. The results of the analysis showed that of the 21 genotypes tested, ICCRI 03, BAL 209, and KW 411 showed horizontal branching type; Sulawesi 1 and Sulawesi 3 showed vertical branching type, while the other 16 genotypes had intermediate branching types. Cocoa clones with a vertical branching type can be planted in denser spacing compared to cocoa clones with a horizontal branching type. The population per hectare of clones with vertical branching type can be increased 3 to 4 times when compared to clones with horizontal branching type.
Types of figurative language found in bon jovi song lyrics
Authors: Lembu Eufronius Sarino , Pratiwi Desak Putu Eka , Candra Komang Dian Puspita 
Published: January 2022

This study aim to analysis types Figurative language and their meaning found in Bon Jovi song lyrics. In every song we can find many languages that contain figurative language because that’s the important element in the song to deliver the meaning to the listener. `The data source of this study were taken from https://w.azlyrics.com/ which consists of several lyrics that taken by the researcher. The data were collected used the observation method. Whereas the descriptive qualitative method was used to analyse the data in this study. The data were analysed base on theory of figurative language by Knickerbocker and Reninger (1963) and the meaning used the theory by Barthes (1964). The finding of the study analysis 10 types of figurative language base on the song from 2 albums of Bon jovi song lyrics such as 4 types of similes ,1 types of metaphors ,2 types of , 1 type of metonymy ,9 types of hyperboles ,2 types of irony,1 type of allusion 1 type of paradox with the percentage unfortunately, the writer didn’t dead metaphor and Synecdoche in the song lyrics. The types of figurative language contain with the denotative and connotative meaning.
Incidencia del Emprendimiento en el Fortalecimiento de la Gestión Administrativa y Organizacional de las Artesanas Wayuu
Authors: Lopesierra - Orozco Jaider Jesús , Rocha - Camargo Juan Carlos , Arredondo - González Ronald 
Published: January 2022

La presente investigación tuvo como finalidad analizar la incidencia del emprendimiento en el fortalecimiento de la gestión administrativa y organizacional de las artesanas Wayuu, abordado desde un enfoque costumbrista, ancestral que permita incidir en la transformación de unas costumbres heredadas generacionalmente, lo que afecta de cierta forma el que hacer empresarial, en cuanto a procesos administrativos, operativos, comerciales y de producción, cabe destacar que con base a su cosmovisión cultural y social en su organización clanil, prevalece el matriarcado, denotado en funciones jerárquicas liderada por la mujer, lo que permite propiciar ciertas acciones organizacionales empíricas e informales como se puede observar en la práctica de la tejeduría, proceso que es liderado única y exclusivamente por la mujer Wayuu, es así como atreves de la funcionalidad y oportunidad que brinda el emprendimiento se buscó el fortalecimiento, estructuración y organización de los procesos con base a las normas y principios establecidos por expertos en el contexto de la administración, con la finalidad de que los procesos productivo liderados por clanes wayuu gocen de una organización empresarial que les permita producir y comercializar productos con altos estándares de calidad e innovación, y así contribuir en la generación de empleo, rendimientos económicos y financieros.
Students' motivation to attend group guidance based on gender and ethnic
Authors: Hariko Rezki , Nirwana Herman , Fadli Rima Pratiwi , Ifdil Ifdil , Hastiani Hastiani , Febriani Rahmi Dwi 
Published: January 2022

Although group guidance is believed to be an effective and efficient service to facilitate the development of positive aspects and prevention of negative aspects of students, the frequency of its use for students is not optimal. This study aims to analyze student motivation to follow group guidance and differences in their motivation based on gender and ethnicity. The study used a comparative descriptive method. A total of 690 samples were involved in write-paper-and-pencil questionnaires, namely the students' motivation scale to attend group guidance, which was designed based on the Likert Scale model. We analyzed data using descriptive statistics and different test analysis using independent samples t-test and Bayesian method by applying JASP software. Analysis results showed that most students have the prime motivation to follow group guidance and there are significant differences in student motivation to follow group guidance based on gender, but in terms of ethnicity did not show any significant differences. School counselor can implement the findings of this study in determining group members in group guidance services.
Somatic distress, mental health and psychological resilience among cancer patients during the Covid-19 pandemic
Authors: Sağaltıcı Eser , Sönmez Özcan , Karcı Ebru , Şahin Şengül Kocamer , Erturk Arzu 
Published: January 2022

We aimed to investigate the somatic distress and psychological symptoms levels of cancer patients, and analyze the influencing factors on somatic distress during COVID-19 pandemic. This cross-sectional study included 216 eligible cancer patients. The Patient Health Questionnaire-15, Post-Traumatic Stress Disorder (PTSD) Checklist for DSM-5, The Depression, Anxiety and Stress Scale-21, the Brief Resilience Scale, the Stressful Life Events List due to Pandemic were administered to the participants. The moderate to severe somatic distress rate was % 38 and probable PTSD rate was 20.4%. Depression, anxiety and stress symptoms were 36.1%, 49.1% and 45.4%, respectively, from mild to extremely severe. There were substantial association between somatic symptoms severity and high PTSD, anxiety, depression, and stress symptoms levels. Low education, high anxiety levels, high experience stressful life events, and low psychological resilience predicted high somatic distress. This study demonstrates the high risk of somatic distress, PTSD, depression, anxiety and stress in patients with cancer during the pandemic. In addition, somatic distress may indicate high levels of psychological symptoms, high experience stressful life events, and low psychological resilience. It underscores the need to assess psychological status during the pandemic, especially those with high level somatic symptoms.
Dengue e COVID-19 no Brasil: uma abordagem sistêmica
Authors: Cruz Neto João , Leite Alencar Lara Pereira , Penha de Lima Maria Gisleide , Gonçalves Leonel Ana Camila , Oliveira Joseph Dimas de 
Published: January 2022

O objetivo do estudo foi analisar os casos de COVID-19 e dengue nos estados brasileiros. Trata-se de um estudo ecológico realizado nos 26 estados do Brasil e o Distrito Federal. Os casos foram consolidados até a 19ª semana epidemiológica de 2021 e emergiram dos sites oficiais do governo brasileiro. Os dados foram analisados por testes estatísticos no Software R com significância de 5%. Houve significância para prevalência da dengue e prevalência da COVID-19 (p=0.01), casos de dengue e óbitos por COVID-19 (p=0.00), prevalência de dengue e o número de casos de dengue (p=0.00), óbitos por dengue (p=0.00), e letalidade por dengue (p=0.00). Aponta-se uma manifestação nacional entre as doenças sendo necessárias medidas de mitigação dos casos, diagnóstico diferencial e estratégias de prevenção, bem como ampliação do serviço de notificação com promoção da vigilância epidemiológica.
Mediation of Candida species growth and virulence by the proinflammatory cytokine IL-6
Authors: Ciurea Cristina Nicoleta , Kosovski Irina-Bianca , Toma Felicia , Mareș Mihai , Tudor Bianca , Man Adrian 
Published: January 2022

Abstract
Interleukin-6 (IL-6) is a cytokine with pleiotropic effects that might also influence the virulence traits of some microorganisms, but its direct influence over Candida spp. is currently unknown. The objective of the study is to determine the influence of IL-6 (250 pg/ml) on the growth rate and biofilm formation of C. albicans, C. parapsilosis, C. krusei, C. auris, and C. guilliermondii, as well as to analyze the influence of this citokine on the expression of three virulence genes (ALS3, HSP70, SAP2), respectively on the germ tube formation ability of C. albicans. The influence of IL-6 on growth rate was assessed by incubating the fungal cells in presence of IL-6 for 48 hours and assessing the optical density of the samples at five timepoints. The biofilm production in presence of IL-6 was studied in microtiter plates, using crystal-violet assay, the intensity of biofilms being evaluated by spectrophotometry. The expression of ALS3, HSP70, and SAP2 in C. albicans was studied by RT-PCR, reported to ACT1 housekeeping gene. The germ-tube test was performed to assess the influence of IL-6 on the filamentation rate of C. albicans. All test results were normalized against control, without added IL-6. The results showed that IL-6 influences the growth rate of C. albicans, C. parapsilosis, C. krusei, C. auris, and C. guilliermondii in a time-dependent way. Also, IL-6 inhibited the formation of biofilms for C. albicans and C. guilliermondii. In C. albicans cells, IL-6 induced upregulation of ALS3 and HSP70, while it down-regulated the SAP2 gene. IL-6 did not influence the germ-tube formation in C. albicans. In conclusion, IL-6 might exert, in vitro, direct effects on the virulence traits of Candida spp., and its influence is dependent on the exposure time. Non-albicans Candida species presented particular responses to IL-6.
E-cigarette and alternative tobacco products consumption among adolescents in Chisinau, Republic of Moldova – A repeated cross-sectional study
Authors: Topada Aculina , Nădășan Valentin , Tarcea Monica , Ábrám Zoltán 
Published: January 2022

Abstract

Objective: The main objective of the study was to evaluate e-cigarette and alternative tobacco product use in ninth-grade students from Chisinau.

Methods: The repeated cross-sectional study collected data using a questionnaire administered in 2015 and 2018 among ninth-grade students in Chisinau, Republic of Moldova. Absolute and relative frequencies of electronic cigarettes and alternative tobacco products ever use were calculated and 2015 data were compared with those collected in 2018.

Results: The percentage of participants ever using electronic cigarettes in 2015 and 2018 respectively was 42.9% and 59.5% (p=0.001), ever using cigars was 14.9% and 15.9% (p=0.684), ever using pipes was 3.3% and 4.9% (p=0.205), ever using hookah was 17.4% and 21.7% (p=0.086), ever using chewing tobacco was 11.6% and 3.9% (p=0.039), ever using snus was 4.1% and 6.2% (p=0.135), and ever using snuff was 0.5% and 1.1% respectively (p=0.518). Exposure of participants to messages promoting electronic cigarettes was 31.0% in 2015 and 65.8% in 2018 (p<0.0001). Consumption of electronic cigarettes was significantly associated with sex (boys 62.8% vs. girls 43.6%), school performance (low grades 61.5% vs. high grades 50.0%), exposure to pro e-cigarette messages (exposed 61.4% vs. not exposed 44.0%), perceived e-cigarettes harmfulness (less harmful 66.9% vs. more harmful 39.7%), and use of conventional cigarettes (ever tried 79.8% vs. never tried 24.6%).

Conclusions: The study showed an important, statistically significant increase in the consumption of electronic cigarettes among ninth-grade students in Chisinau city, from 2015 to 2018 and an increased exposure to electronic cigarette advertising.
The Five-Factor Model Approach to Hypertensive Patients: A Case Control Study
Authors: Lakatos Eva-Katalin , Nireștean Aurel 
Published: January 2022

Abstract
Objectives: The aim of this case-control pilot study was to examine whether there are differences in personality characteristics between hypertensive and normotensive individuals in terms of the Five-Factor Model (FFM).
Methods: 71 individuals with primary hypertension were compared with 84 normotensive individuals on the DECAS personality inventory, assessing the five basic dimensions of personality according to the FFM.
Results: Agreeableness and emotional stability were associated with hypertension (p-0,0001 for both). Hypertensive individuals showed low and very low agreeableness and emotional stability whereas normotensives scored medium and high in these two dimensions. Lower emotional stability was a risk factor for hypertension (OR=4.51, CI 95%=2.18-9.35). There were no significant differences in openness, extraversion and consciousness between hypertensives and normotensives (p>0.05).
Conclusion: Individuals with low emotional stability/high neuroticism have more than fourfold increased risk of developing hypertension.
Clinical and Surgical Aspects of Meningothelial Meningioma in Practice and the Implications of Brain-It Summer School
Authors: Săceleanu Mircea-Vicențiu , Țeposu Bogdan-Nicolae , Joarză Alina-Adela , Bîrsan Alexandru , Săceleanu Adriana 
Published: January 2022

Abstract
Mrs. F.M, a 77-year-old woman with prior diagnosis of Alzheimer disease, temporal lobe epilepsy, conversion disorder and essential familial hypercholesterolemia, presented for 2 months diffuse headache and vertigo, and in the past week, left brachial monoparesis and episodic amnesia become apparent, with progressive worsening and no improvement with medication therapy. The CT/MRI findings constituted a real challenge even for experienced practitioners. This article is hereby designed to meet the needs and necessities of young doctors within BrainIT international summer school.
Cervical Spinal Cord Transection (SCT) Increases Gastric Compliance in Anesthetized Rats
Authors: Fodor Radu , Bratu Dan Georgian , Ionescu Călin , Noor Hassan , Cheregi Cornel , Mureșan Mihai 
Published: January 2022

Abstract
Spinal cord injury (SCI) can markedly alter the autonomic nervous system’s functions. It immediately causes autonomic and somatic hypo- or arreflexia, a state known as spinal shock. SCI determines the enhancement of two gastric reflexes that appear in normal conditions: the receptive and adaptative reflexes. Furthermore, this study also tried to evaluate the causes that led to such modifications: either vagal control, nitric oxide (NO)-pathways or intestine-intestinal reflexes. Male Wistar rats (N=25) were subjected to laminectomy (Sham group) or laminectomy + complete Spinal Cord Transection (SCT), between C7 and T1 vertebrae under anesthesia (SCT group). Before the surgery, the rats had water and food ad libitum; after the surgery, rats were fasted for 24 hours, still having access to water. The next day, all animals were subjected to a catheterism of their right carotid artery, a tracheostomy and a flexible balloon introduction down to the stomach’s fundix region, also under anesthesia. Rats were connected to a Power-Lab® system, via a pressure transducer (in order to measure the arterial pressure – MAP - and the heart rate - HR), and to a modified Plethysmometer (in order to measure the fundical gastric volume - GV variation). Vagal control was studied via cervical vagotomy; NO-mediation - via NO synthesis inhibitors (L-NAME); intestinointestinal reflexes - by using laxatives (Lactulone). Statistical analysis revealed, in some cases, that GV is significantly (p<0.05) augmented in SCT rats (2,4±0,09; 3,1±0,05; 3,7±0,06 ml) than in Sham (2,2±0,12; 2,9±0,12; 3,3±0,15 ml). Nevertheless, MAP and HR, were subsequently lower (p<0.05) in SCT (63,5±21,1mm Hg; 227,1±25,2 BPM) than in the control group (88,2±14,4mm Hg; 427,0±19,2 BPM). In summary, the increase of GV in SCT, seems to involve vagal pathways and/or NO-mediation, but still not neglecting the colic-gastric reflexes.