bluuebunny/crossref_metadata_2025_split huggingface dataset:
COVID-19 pandemic: Prevalence of depression, anxiety, and stress symptoms among Brazilian psychologists
Authors: Campos Juliana Alvares Duarte Bonini , Campos Lucas Arrais , Martins Bianca Gonzalez , de Oliveira Adriano Palomino , Navarro Fabiana Maria , dos Santos Simone Cristina , da Costa Josilene , Prado Oliver Zancul , Marôco João 
Published: December 2022

IntroductionSymptoms related to mental health disorders became the background of the COVID-19 pandemic, and psychologists had to adapt to the demands, while they themselves were exposed to the pandemic and its stressors.ObjectivesTo identify demographic and professional characteristics of Brazilian psychologists in different phases of pandemic and their reported care practices, concerns, and symptoms.MethodsThis was an observational study conducted online in four independent phases with no pairing among the samples (May/June 2020, n = 263; November/December 2020, n = 131; May/June 2021, n = 378; November/December 2021, n = 222). Depression, Anxiety and Stress Scale was used. The validity and reliability of the data obtained with the DASS-21 were attested to by confirmatory factor analysis. Basic lexographic and similarity analysis were conducted to obtain textual information. Prevalence of variables was estimated and compared between phases using the z-test (α = 5%). Similarity analysis was performed to identify the psychologists’ concerns.ResultsMost of participants were women and were self-employed or employed. There was rapid adjustment to remote work and more than 70% reported changes in their mental health since the onset of pandemic. One in four participants had a previous mental health disorder, and there was a high prevalence of symptoms such as anxiety, fear, and angst. The prevalence of professionals who reported not caring about their own mental health was significant. In 2020, one cluster (health) of concern was identified, while in 2021 there were three clusters (health, family, and COVID-19). The prevalence of depression, anxiety, and stress symptoms was high and did not change during the pandemic.ConclusionsPsychologists adapted to the demands of the population in the face of the pandemic. However, there was a high prevalence of mental health symptoms and a disregard for self-care among these professionals.
The influence of social support on the physical exercise behavior of college students: The mediating role of self-efficacy
Authors: Zhang Yan , Hasibagen  , Zhang Chang 
Published: December 2022

ObjectivesTo study the influencing factors on college students’ physical exercise behavior and the mediating relationship of self-efficacy based on the theory of social support and self-efficacy; to provide theoretical support and practical guidance for college students engaging independently in physical exercise.MethodsA total of 1,440 college students from six universities in the Inner Mongolia Autonomous Region of China were selected as the research objects, and three scales (Self-Efficacy Scale, Social Support Scale, and Physical Exercise Rating Scale) were used to construct a structural equation model.Results(1) A comprehensive sports facility environment is conducive to college students’ physical activities and the emotional support of friends and family and the campus cultural atmosphere cannot be ignored. (2) Peer support has a direct impact on physical exercise behavior, family support and school support indirectly affect college students’ physical exercise behavior, based on the intermediary role of self-efficacy. (3) According to the total effect, social support was ranked as school support (0.444), peer support (0.312), and family support (0.145).ConclusionSocial support not only directly affects physical exercise behavior but also indirectly affects physical exercise behavior based on the mediating effect of self-efficacy.
Psychological distress and associated factors among Palestinian advanced cancer patients: A cross-sectional study
Authors: Abu-Odah Hammoda , Molassiotis Alex , Zhao Ivy Y. , Su Jing Jing , Allsop Matthew J. 
Published: December 2022

ObjectiveThere is limited research exploring the experiences of people living with advanced cancer in the Gaza Strip (GS), Palestine. Thus, this study aimed to determine the level of psychological distress, anxiety, and depression among advanced cancer patients in the GS and identify factors associated with a high level of distress.Materials and methodsA secondary analysis was performed using primary data from a larger study focusing on supportive care needs in advanced cancer patients in GS. Three hundred sixty-one patients agreed to participate and filled out the Distress Thermometer (DT) and the Hospital Anxiety and Depression Scale (HADS). Multivariate logistic regression was conducted to identify factors associated with high distress levels.ResultsOver two-thirds of advanced cancer patients (70.6%) reported a high level of distress. They also reported a significantly higher distress level than patients with early cancer (96.5 vs. 3.5%; p = 0.001). About 92.8% of participants reported depression and anxiety symptoms. Physical, emotional, and practical problems were the primary sources of distress. Breast cancer patients were more likely to have psychological distress than colon and stomach cancer patients. Newly diagnosed patients had a higher level of anxiety, depression, and distress than those who had a cancer diagnosis for an extended period.ConclusionPatients with advanced cancer in the GS exhibited a significantly higher level of psychological distress, depression and anxiety than patients with advanced cancer elsewhere. Efforts should be made to identify psychological distress as a routine part of oncology practice. Future research should further explore the causes of psychological distress in cancer patients in conflict zones and feasible mitigation strategies.
Intimate partner violence against ever-partnered women in Europe: Prevalence and associated factors—Results from the violence against women EU-wide survey
Authors: Barbier Alice , Chariot Patrick , Lefèvre Thomas 
Published: December 2022

Study questionsTo describe the prevalence of physical, sexual, and psychological intimate partner violence (IPV) against women in the European Union (EU) and to search for their determinants among demographic, socioeconomic, health-related factors, and partner characteristics.MethodsObservational study. Data from the violence against women survey, the first study conducted in the EU, which simultaneously measured all dimensions of IPV and many characteristics. The EU Agency for Fundamental Rights randomly conducted face-to-face interviews among the 28 countries with 42,002 women aged 18–74 who resided in the survey country and spoke the language. IPV is defined by a positive answer to at least one question about physical, sexual, or psychological violence perpetrated by a current or ex-partner.FindingsAmong the 40,357 women having already been in a relationship, 51.7% (51.2–52.2) reported having been victims of violence in their lifetime. The prevalence of physical, sexual, and psychological IPV was, respectively, 20.0% (19.6–20.4), 8.4% (8.2–8.7), and 48.5% (48.1–49.0). Women, who were younger, employed, had highly qualified work, had at least one immigrant parent, lived in an urban setting, were unmarried, separated, divorced, widowed, childless, cohabited with a partner, and others over the age of 18, had worse self-perceived health, or a history of violence before the age of 15 were more likely to report IPV. It was the same when their partners had a lower level of education, no work, were home staying, earned less than they did, were involved in 10 years of relationship, were frequently drunk, or were violent otherwise.Major implicationThe lifetime prevalence of reported IPV among women in Europe is high and likely underestimated. The results emphasize the importance of a comprehensive definition of IPV and partners' characteristics. They highlight socioeconomic differences and poorer health status for victims of IPV.
The impact of the COVID-19 pandemic on physical activity, life satisfaction, anxiety, stress perception and coping strategies in student-athletes: A comparison between Belarus and Poland–countries with a different approach of anti-pandemic measures
Authors: Shpakou Andrei , Sokołowska Dorota , Krajewska-Kułak Elżbieta , Cybulski Mateusz , Kowalewska Beata , Korpak Filip , Surkov Sergei , Owoc Jakub , Krakowiak Jan , Kowalczuk Krystyna 
Published: December 2022

BackgroundMore than two years of the COVID-19 pandemic has changed lives of people around the world and had a profound impact on the field of sports. This has resulted in decreased physical activity (PA) and changes in mental health. The goal was to assess self-reported physical activity, life satisfaction, perceived stress, choice of coping strategies and their correlations among student athletes from two neighboring countries facing different anti-pandemic strategies.MethodsCross-sectional surveys using standardized questionnaires: International Physical Activity Questionnaire—Short Form (IPAQ-SF), Satisfaction With Life Scale (SWLS), State-Trait Anxiety Inventory (STAI), Perceived Stress Scale (PSS-10), and Coping Orientation to Problems Experienced (Mini-COPE) to compare 600 students from Physical Education and Sports departments of universities in Belarus (n = 333), where restrictions were found to be less stringent than in neighboring Poland (n = 267).ResultsMinor differences in physical activities between both countries indicate that student athletes have adapted fairly quickly and found ways to keep their PA at a fairly high level. Nevertheless, higher PA was reported in the group of student athletes from Belarus. PA levels correlated with life satisfaction, anxiety and stress levels. Female students from Poland reported lower satisfaction with their lives. Their perception of stress was twice as high as that of their Belarusian counterparts. The most common coping strategy in both groups was active coping. Polish respondents less frequently used strategies of avoiding problems and seeking outside support.ConclusionThe level of physical activity and well-being of student athletes are associated with increased mental health and coping with stress. They also contribute to prevention of affective disorders during the COVID-19 pandemic. Moreover, it is dependent on the country's anti-pandemic policies.
Efficacy and safety of hypoglycemic agents on gestational diabetes mellitus in women: A Bayesian network analysis of randomized controlled trials
Authors: Wang Ting , Jing Yingyu , Guo Haonan , Xu Jing , Wang Man , Huang Lili , Chen Huan , Cui Wei , Song Lin , Liu Xiang , Sun Bo , Wang Ning 
Published: December 2022

ObjectiveTo compare the efficacy and safety of metformin, glyburide, and insulin for GDM, we conducted a subgroup analysis of outcomes for women with GDM according to the International Association of Diabetes and Pregnancy Study Groups (IADPSG) diagnostic criteria.MethodsWe searched the NCBI, Embase, and Web of Science databases from inception to March 2022. Randomized controlled trials (RCTs) that compared the outcomes of hypoglycemic agents in women with GDM were included. Bayesian network analysis was employed.ResultsA total of 29 RCTs were included. Metformin was estimated to lead to a slight improvement in total gestational weight gain (WMD – 1.24 kg, 95% CI −2.38, −0.09), a risk of unmet treatment target in the sensitivity analysis (OR 34.50, 95% CI 1.18–791.37) than insulin. The estimated effect of metformin showed improvements in birth weight than insulin (WMD – 102.58 g, 95% CI −180.45 to −25.49) and glyburide (WMD – 137.84 g, 95% CI −255.31 to −25.45), for hypoglycemia within 1 h of birth than insulin (OR 0.65, 95% CI 0.47 to 0.84). The improvement in the estimated effect of metformin for hypoglycemia within 1 h of birth still existed when compared with glyburide (OR 0.41, 95% CI 0.26 to 0.66), whether in the IADPSG group (OR 0.33, 95% CI 0.12 to 0.92) or not (OR 0.43, 95% CI 0.20 to 0.98).ConclusionMetformin is beneficial for GDM women to control total GWG compared with insulin, regulate fetal birth weight more than insulin and glyburide, and increase the risk of unmet treatment targets compared with insulin. Compared to metformin, glyburide is associated with neonatal hypoglycemia.
Gaps in the implementation of national core elements for sustainable antimicrobial use in the WHO-African region
Authors: Fuller Walter L. , Aboderin Aaron O. , Yahaya Ali , Adeyemo Adeyemi T. , Gahimbare Laetitia , Kapona Otridah , Hamzat Omotayo T. , Bassoum Oumar 
Published: December 2022

BackgroundAntimicrobial resistance (AMR) has emerged as a leading global health and economic threat of the 21st century, with Africa bearing the greatest burden of mortality from drug-resistant infections. Optimization of the use of antimicrobials is a core strategic element of the response to AMR, addressing misuse and overuse as primary drivers. Effectively, this requires the whole society comprising not only healthcare professionals but also the public, as well as the government, to engage in a bottom-up and a top-down approach. We determined the progress of African national governments in optimizing antimicrobial drug use.MethodsFrom September 2021 to June 2022, all 47 member states of the World Health Organization African region (WHO AFRO) were invited to participate in a survey determining the implementation of strategies to optimize antimicrobial use (AMU). We used the WHO antimicrobial stewardship (AMS) assessment tool, National core elements—A checklist to guide the country in identifying existing national core elements for the implementation of AMS Programs, to obtain information from national AMR focal persons. The tool consists of four sections—national plans and strategies; regulations and guidelines; awareness, training, and education; and supporting technologies and data—with a total of 33 checklist items, each graded from 0 to 4. The responses were aggregated and analyzed using Microsoft Excel 2020®.ResultsThirty-one (66%) of the 47 countries returned completed forms. Only eight (25.8%) countries have developed a national AMS implementation policy incorporating defined goals, targets, and operational plans. There are no budget lines for AMS activities in 23 (74.2%) countries. The WHO Access, Watch, Reserve (AWaRe) classification of optimizing AMU has been integrated into the national essential medicines list or formulary in 19 (61.3%) countries, while the incorporation of the AMS principles and WHO AWaRe classification into national clinical guidelines for the management of infections is present in only 12 (38.7%) and 11 (34.5%) countries, respectively. Although regulations on the prescription-only sale/dispensing of antibiotics are present in 68% of countries, their enforcement is poor. Systems identifying pathogens and antibiotic susceptibility for optimal use of antibiotics are lacking in 38% of countries.ConclusionIn Africa, wide gaps exist in the governments’ implementation of the core elements of optimizing antimicrobial drug use. Responding to AMR constitutes a long journey, and technical and financial support needs to be deployed to optimize the use of antimicrobials.
Stifle kinematics in 4 dogs with cranial cruciate ligament insufficiency treated by CORA-based leveling osteotomy
Authors: Tinga Selena , Hughes Natalie , Jones Stephen C. , Park Brian , Palm Lindsey , Desaraju Sasank S. , Banks Scott A. , MacArthur Sandra L. , Lewis Daniel D. 
Published: December 2022

ObjectiveThe purpose of this study was to quantify three-dimensional (3D) stifle kinematics during walking in dogs with complete cranial cruciate ligament insufficiency (CCL-I) treated with a CORA-based leveling osteotomy (CBLO).Study designFour client-owned dogs with unilateral complete CCL-I were prospectively enrolled. Custom digital 3D models of the femora and tibiae were created from pre-and postoperative computed tomographic scans for each dog. Lateral view fluoroscopic images were collected during treadmill walking preoperatively and 6 months after CBLO. Results were generated using a 3D-to-2D image registration process. Pre-and postoperative stifle kinematics (craniocaudal translation, extension angle) were compared to that of the unaffected contralateral (control) stifle. Force plate gait analysis was performed, and symmetry indices (SI) were calculated for peak vertical force (PVF) and vertical impulse (VI).ResultsAfter CBLO, craniocaudal femorotibial motion was reduced by a median (range) of 43.0 (17.0–52.6) % over the complete gait cycle. Median (range) PVF SI was 0.49 (0.26–0.56) preoperatively and 0.92 (0.86–1.00) postoperatively, and VI SI was 0.44 (0.20–0.48) preoperatively and 0.92 (0.82–0.99) postoperatively.ConclusionCBLO mitigated but did not fully resolve abnormal craniocaudal translation; lameness was substantially improved at 6 months.
Molecular Cloning and Characterization of a Fasciola gigantica Nuclear Receptor Subfamily 1 (FgNR1)
Authors: Martviset Pongsakorn , Chantree Pathanin , Chaimon Salisa , Torungkitmangmi Nattaya , Prathaphan Parisa , Ruangtong Jittiporn , Sornchuer Phornphan , Thongsepee Nattaya , Sangpairoj Kant , Adisakwattana Poom 
Published: December 2022

Fasciola gigantica, a giant liver fluke, causes tremendous loss to the livestock economy in several regions throughout the world. The situation of drug resistance has been emerging increasingly; therefore, novel drugs and drug targets need to be discovered. The adult F. gigantica inhabits the major bile ducts where bile salts accumulate—these are steroid-like molecules that mediate several physiological processes in organisms through interacting with their specific nuclear receptors. However, the molecular mechanism of the interaction in the parasitic organisms have not been clearly understood. In this study, putative nuclear receptor subfamily 1 of F. gigantica (FgNR1) was identified. Nucleotide and amino acid sequences of the FgNR1 homolog were obtained from the transcriptome of F. gigantica and predicted for properties and functions using bioinformatics. The full-length cDNA was cloned and expressed in the bacterial expression system and then used for immunization. Western analysis and immunolocalization suggested that FgNR1 could be detected in the crude worm antigens and was highly expressed in the caeca and testes of the adult parasite. Moreover, the bile could significantly activate the expression of FgNR1 in cultured parasites. Our results indicated that FgNR1 has high potential for the development of a novel anthelminthic drug in the future.
Cannabis sativa Cannabinoids as Functional Ingredients in Snack Foods—Historical and Developmental Aspects
Authors: Krüger Marlize , van Eeden Tertia , Beswa Daniso 
Published: December 2022

The published health benefits of Cannabis sativa has caught the attention of health-conscious consumers and the food industry. Historically, seeds have long been utilized as a food source and currently there is an increasing number of edibles on the market that contain cannabis. Cannabinoids include the psychoactive constituent, delta-9-tetrahydrocannabinol (THC), and the non-psychoactive cannabidiol (CBD) that are both compounds of interest in Cannabis sativa. This paper looks at the distribution of nutrients and phytocannabinoids in low-THC Cannabis sativa, the historical uses of hemp, cannabis edibles, and the possible side-effects and concerns related to cannabis edibles. Several authors have pointed out that even though the use of cannabis edibles is considered safe, it is important to mention their possible side-effects and any concerns related to its consumption that negatively influence consumer acceptance of cannabis edibles. Such risks include unintentional overdose by adults and accidental ingestion by children and adolescents resulting in serious adverse effects. Therefore, cannabis edibles should be specifically packaged and labelled to differentiate them from known similar non-cannabis edibles so that, together with tamperproof packaging, these measures reduce the appeal of these products to children.
PENGARUH FAKTOR-FAKTOR PRODUKSI TERHADAP PENINGKATAN PRODUKSI KAKAO DI DESA KUNYI KECAMATAN ANREAPI KABUPATEN POLEWALI MANDAR
Authors: Otto Radus Marselius , Pagala Muh. Arman Yamin , Kusmiah Nurhaya 
Published: December 2022

Penelitian dilaksanakan di Desa Kunyi Kecamatan Anreapi Kabupaten Polewali Mandar. Menggunakan sumber data primer dan sekunder dengan metode pengambilan data yaitu survey, kuesioner, observasi, wawancara, dan dokumentasi. Sampel penelitian menggunakan metode Arikunto dengan mengambil 25% dari 352 petani kakao. Metode analisis data yang digunakan yaitu Regresi Linier Berganda. Adapun tujuan dari penelitian ini yaitu Menganalisis pengaruh fakor Pemupukan, Peremajaan, Pemangkasan, dan Luas Lahan terhadap peningkatan produksi buah kakao Desa Kunyi Kecamatan Anreapi, Menganalisis seberapa besar pengaruh Pemupukan, Peremajaan, Pemangkasan serta Luas Lahan terhadap peningkatan produksi buah kakao di desa Kunyi kecamatan Anreapi, dan Menganalisis Bagaimana pengaruh secara Parsial dan Simultan faktor Pemupukan, Peremajaan, Pemangkasan, dan Luas Lahan terhadap peningkatan produksi buah kakao di Desa Kunyi Kecamatan Anreapi. Hasil penelitian setelah melakukan pengujian secara Parsial (Uji T) variabel Pemupukan (X1), Peremajaan (X2), dan Luas Lahan (X4) dinyatakan berpengaruh terhadap Produksi kakao, sedangkan variabel Pemangkasan (X3) dinyatakan tidak terdapat berpengaruh. Kemudian untuk pengujian secara Simultan (Uji F) keempat variabel yakni Pemupukan, Peremajaan, Pemangkasan, dan Luas Lahan dinyatakan berpengaruh secara simultan atau berpengaruh secara bersamaan terhadap Produksi buah kakao di Desa Kunyi Kecamatan Anreapi Kabupaten Polewali Mandar dengan melihat nilai F hitung 161,324 > nilai F tabel 2,48 dan nilai Sig 0,000 < nilai Toleransi 0,05. Berdasarkan hasil Analisis Korelasi, maka diperoleh angka Adjusted R Square sebesar 0,881 sehingga dapat diartikan bahwa terdapat pengaruh dari variabel Pemupukan, Pemangksan, Peremajaan, dan Luas Lahan sebesar 88% terhadap Produksi buah kakao (Y) di Desa Kunyi Kecamatan Anreapi Kabupaten Polewali Mandar.
ANALISIS KANDUNGAN PROTEIN DAN DAYA TERIMA PADA BISKUIT TEPUNG IKAN TERI (Stolephorus sp) DAN ISOLAT PROTEIN KEDELAI (Glycine mix) UNTUK PMT-P BALITA GIZI KURANG
Authors: Ratnasari Diah , Wahyani Anggray Duvita 
Published: December 2022

AbstrakSalah satu potensi perikanan laut di Indonesia adalah ikan teri ( Stolephorus Sp ) Pemanfaatan ikan teri belum maksimal, upaya dikembangkan melalui penganekaragaman ikan teri salah satunya untuk pembuatan tepung ikan. Tepung Ikan teri diolah menjadi biskuit berpotensi menjadi Pemberian Makanan Tambahan (PMT) yang tepat untuk balita gizi kurang dan disubstitusi dengan isolat protein kedelai yang dimanfaatkan dalam pembuatan biskuit Tujuan penelitian ini yaitu untuk mengetahui pengaruh substitusi tepung ikan teri dan isolat protein kedelai terhadap nilai gizi dan daya terima biskuit. Metode yang digunakan dalam penelitian ini menggunakan metode eksperimental dengan satu faktor yang dicoba yaitu proporsi tepung ikan teri dan isolat protein kedelai yang terdiri dari 5 taraf, yaitu: P1 = 100% : 0%; P2 = 80% : 20%; P3 = 60% : 40%; P4 = 40% : 60%; P5 =20% : 80%.Rancangan percobaan yang digunakan dalam penelitian ini adalah Rancangan Acak Lengkap. dengan 3 kali pengulangan. Hasil penelitian diketahui bahwa rata-rata kandungan protein tertinggi adalah P5 (formula 5) Hasil uji ANOVA diketahui p< 0,05 sehinngga dapat disimpulkan terdapat perbedaan kandungan protein pada tiap perlakuan Demikian pula dengan proporsi ikan teri dan isolat protein kedelai berpengaruh terhadap daya terima biskuit yaitu Rasa, Warna, aroma dan Tekstur biskuit (p<0,05). Kata kunci : tepung ikan teri, isolat protein kedelai , biskuit