bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of treatment of severe rheumatoid arthritis patients with biological agents and JAK-STAT inhibitors. An observational study
Authors: Wisłowska Małgorzata 
Published: May 2022

IntroductionTreatment of severe rheumatoid arthritis (RA) is currently based either on biological agents or Janus kinase/signal transducer and activator of transcription inhibitors, most often in combination with methotrexate (MTX).Aim of the studyThe aim of the study was to compare the effectiveness and side effects of bio-
logic disease-modifying antirheumatic drugs (bDMARDs) and targeted synthetic (ts) DMARDs treatment.Material and methodsThe analysis included 108 RA patients with active disease treated with MTX 25 mg per week. Eighty patients (group I) were treated with bDMARDs and 28 patients (group II) with JAK-STAT inhibitors. The duration of morning stiffness, pain on Visual Analogue Scale (VAS), 28-joints Disease Activity Score (DAS28) and Simplified Disease Activity Score (SDAI) were assessed. Classical radiographic images of patients’ hands and feet using the Larsen and Dale’s criteria were evaluated. The effects of treatment with bDMARDs and tsDMARDs were analyzed.ResultsAll studied patients presented at least Larsen and Dale’s stage 3 of X-ray changes typical for RA. There were no statistically significant differences in disease duration, ESR, CRP, DAS28
and SDAI values between studied groups. Patients from group II previously used higher numbers of bDMARDs than group I treated with bDMARDs. Low disease activity after treatment was achieved by all patients; therefore patients from group II (treated with tsDMARDs) achieved lower values of patients’ global assessment on VAS.
Dampak Makanan Cepat Saji Terhadap Kesehatan pada Mahasiswa Program Studi “X” Perguruan Tinggi “Y”
Authors: Laksono Rizky Agung , Mukti Nurul Dwi , Nurhamidah Didah 
Published: May 2022

Abstrak
Latar belakang: Makanan cepat saji merupakan makanan yang bisa disajikan dengan waktu yang sesingkat mungkin. Makanan cepat saji memiliki banyak sekali ragam jenis, dari makanan ringan hingga berat. Sejalan dengan perkembangan pada jumlah dan jenis makanan, kebiasaan masyarakat dalam mengonsumsi makanan semakin beraneka ragam termasuk kegemaran mengonsumsi makanan cepat saji. Padahal jika dikonsumsi berlebihan, makanan cepat saji dapat mengakibatkan berbagai gangguan kesehatan. Studi ini ditujukan untuk mengetahui dampak konsumsi makanan cepat saji pada mahasiswa.
Metode: Penelitian cross sectional ini dilakukan terhadap kesehatan mahasiswa Program Studi “X” Perguruan Tinggi “Y”. Metode pengumpulan data menggunakan teknik penyebaran angket secara daring yang dimulai sejak 17 Oktober 2021 terhadap 28 mahasiswa. Data dianalisis secara deskriptif.
Hasil: Hasil penelitian menunjukkan bahwa 53,6% mahasiswa setuju dengan konsumsi makanan cepat saji, 64,3% mengaku mengalami gangguan tenggorokan 53,6% mahasiswa merasa mengantuk setelah konsumsi makanan cepat saji, dan 64,3% mahasiswa mengaku mengalami peningkatan berat badan karena tingginya frekuensi konsumsi makanan cepat saji
Kesimpulan: Studi ini menemukan bahwa mahasiswa mengeluhkan mengalami dampak negatif dari makanan cepat saji seperti kenaikan berat badan, gangguan tenggorokan, dan merasa mengantuk.
Kata kunci: Dampak, Kesehatan, Makanan cepat saji
Abstract
Background: Fast food is food that can be served in the shortest possible time. Fast food has a wide variety of types, from light to heavy meals. In line with developments in the amount and type of food, people's habits in consuming food are increasingly diverse, including their fondness for eating fast food. In fact, if consumed in excess, fast food can cause various health problems. This study aimed to determine the impact of fast food consumption on students.
Methods: This cross-sectional study was conducted in “X” department University of “Y”. Online questionnaire was used to collected the data on October 17, 2021 in 28 students. The data were analyzed descriptively.
Results: The results showed that 53.6% of students agreed with the consumption of fast food, 64.3% admitted to having throat problems, 53.6% of students felt sleepy after consuming fast food, and 64.3% of students admitted that they experienced weight gain because of the high frequency of consumption of fast food
Conclusion: This study found that college students complained of experiencing negative effects from fast food snacks such as weight gain, throat disorders, and feeling sleepy.
Keywords: Fast food, Health, Impact
Лусине Мовсисян․ «Армяно-азербайджанский разговорник»
Authors: Зограбян Эдуард 
Published: May 2022

В первые два десятилетия 21-го века в южнокавказском регионе произошли региональные и макрорегиональные изменения. В частности, в результате	44-дневной	Арцахской	войны, развязанной 27 сентября 2020г. азербайджанотурецкими	вооружёнными	силами	и террористическими наемными бандами, на Южном Кавказе	изменилась	картина	сложившегося	в прошлом баланса сил. Резко увеличилось влияние Турции и России в региональных процессах, существенно	усилилась	роль	политического влияния Азербайджана, появились ощутимые риски	в	сфере	обеспечения	безопасности Арцахской и Армянской Республик. В новой геополитической ситуации необходимо утвердить существующие тенденции регионального развития с точки зрения национальных интересов Армении и Арцаха, и на этой основе выработать реалистическую политику безопасности и национальных интересов.
Alternando derechos. Acerca de cómo la Campaña anti-trata eliminó una categoría de trabajadoras
Authors: Daich Deborah 
Published: May 2022

Desde que, en el 2012, se reformara la ley de trata argentina, casi todos los asuntos relacionados con el mercado del sexo fueron teñidos de suspicacias y leídos en clave de violencia. Así, en nombre del combate a la trata de personas, en el 2016 la Ciudad de Buenos Aires prohibió una antigua y reconocida categoría laboral: las empleadas contratadas para alternar o bailar con los clientes de nightclubs y whiskerías, y estimularlos a hacer gastos, copas, en su compañía. En el discurso de los legisladores, el alterne fue entendido como prostitución (y como un caso de violencia contra las mujeres), y también como una fachada para la trata de personas. ¿Cómo es que la campaña anti-trata pudo eliminar esta categoría sin que hubiera mayores repercusiones? ¿Qué pasó con las trabajadoras y su sindicato? ¿Qué tenían los feminismos para decir al respecto? Este artículo intenta dar respuesta a estos interrogantes basándose en trabajo de campo realizado entre los años 2013 y 2019
Resist, Regulate, Reimagine, and Reinforce: How Social Workers can Advocate for Digital Inclusion
Authors: Dillard Sarah 
Published: May 2022

Algorithms have become more complex, creating artificial intelligence (AI) with the hope it will match human decision making. They are now being used behind-the-scenes in areas such as healthcare, housing and employment, and criminal justice. These computer formulas were created by a privileged set of individuals who often prioritized profitand growth over privacy and protection. This has led to gross injustices that have prevented marginalized communities from receiving care, finding jobs, or gaining freedom. Social workers must be able to digitally advocate for their clients. Resisting these technologies, regulating them through legislation, reimagining the role one can play, and reinforcing what is already experienced in day-to-day interactions with AI are all ways social workers can be involved in creating a world that is digitally inclusive.
Levels and ecological risk assessment of mineral and heavy metals in soils around Nasara Fertilizer Blending Plant, Lafia, Nigeria
Authors: Yerima Emmanuel A. , Itodo Adams U. , Sha’Ato Rufus , Wuana Raymond A 
Published: May 2022

Fertilizer introduction in the right elemental proportion based on plants' nutritional needs has contributed positively to crop production. On the other hand, the leakages during fertilizer blending have contributed to excessive mineral nutrients and traces of heavy metals in the environment. These leakages contaminate water bodies or get into the food chain and bio-cumulate in tissues of living organisms with detrimental effects. This study assessed the impact of fertilizer blending on the level of some mineral and heavy metals in soils around the industrial layout using MP-AES, pollution indices in terms of the geo-accumulation index and contamination factor. The results revealed all of the mineral and heavy metals were detected in the soil in the order of abundance: Fe (10560.77±8.00 mg/kg), P (5252.17±36.15 mg/kg), K (1834.53±13.74 mg/kg), Mg (593.99±13.75 mg/kg), Mn (335.18±1.63 mg/kg), Zn (205.96±1.18 mg/kg), Pb (20.08±0.19 mg/kg) and Cd (6.51±0.06 mg/kg). There was a significant difference in soil quality, mineral and heavy metal content between the test and control soil samples (P < 0.05). The geo-accumulation index showed moderate contamination by phosphorus and strong to extreme contamination by cadmium. The contamination factor showed the soil is moderately contaminated with zinc and lead, considerably contaminated with phosphorus but highly contaminated with cadmium, a very toxic element that distributes so easily in soil and plant tissues. Hence, consumption of crops, fruits and vegetables from the area may likely be at risk. Regular monitoring and effective clean up are recommended.
Non-Hermitian elastodynamics without gain and loss
Authors: Shmuel Gal 
Published: May 2022

Exceptional points are singular states of non-Hermitian systems that generate counterintuitive physics, such as unidirectional transmission and negative refraction. The common approach to access them is by designing parity-time symmetry, which requires a challenging balance between material gain and loss. In this talk, I will show how the unique nature of elastodynamics can be harnessed to mimic gain and loss, generate exceptional points and exotic non-Hermitian wave phenomena, using nothing more than isotropic elastic layers.If time permits, I will briefly show another special feature of elastodynamics, when considering piezoelectric composites. I will show that these composites have effective coupling that does not exist at the microscale, in addition to the Willis coupling. This so-called electromomentum coupling reflects another knob to design the dynamics of the medium, and must be included in order to obtain a physical constitutive description.
Theme of Redemption in Eliot’s The Family Reunion
Authors: Dr. Rani Tiwari  
Published: May 2022

Thomas Sterns Eliot’s second full length poetic play, The Family Reunion is known for its modernity in the matter of expression but medievalism for its contents. Nobody can ignore its importance about its recognition and contribution as a modern play. With this play Eliot presented different kinds of religious modernistic themes. It shows a kind of mirror to the psychological state of human beings. Eliot has presented the spiritual struggle of a lonely character, Harry who is suffering from the hallucination and experiences of having involvement in the act of sinister and desire for its atonement. Harry seems to be unavoidably burdened with the curse which is related to his familial background. Ultimately, he decides to expiate for the same. His feelings of expiation become so strong that he resigns the comfortable ways of life at the place where his family used to reside, the name of the place has been described as Wishwood although none of the wishes seems finely been perfected. He follows the path of self-denial for gaining redemption for himself and his community. Different kinds of mythical and religious images have been used and created to prove its religious concerns. The alteration of Eumenides from hounds of hell is justified not only by “Oresteia of Aeschyus. With this play, Eliot has tried to explain the idea that suffering leans to atonement. Eliot attempted to connect the classical with the modern. This play has two levels of reality. On the surface level, there is a reunion of the family members of Harry. On the deeper level, Furies pursue Harry. Agatha helps Harry to follow the bright angels. He suffers for redemption. This play reflects Eliot’s recurrent preoccupation with Original Sin. The play is remarkable to greater concerns which is related to a purgatorial confrontation between the human spirit and the Divine spirits which may be called as the Supreme Power. Eliot emphasizes the possibility of salvation through redemption.
Clinical, Radiological, and Outcome Characteristics of Acute Pulmonary Embolism: A 5-year Experience from an Academic Tertiary Center
Authors: H Ibrahim Wanis , Al-Shokri Shaikha D , Hussein Musa S , Abu Afifeh Lana M , Karuppasamy Gowri , Parambil Jessiya V , Elasad Farras M , Faris Mohammed E , Abdelghani Mohamed S , Abdellah Ahmed , Kamel Antoun , Ghazouani Hafedh , Ahmad Mushtaq , Aladab Aisha , Danjuma Mohammed I , Raza Tasleem 
Published: May 2022

Background: Acute pulmonary embolism (PE) is a common and potentially life-threatening condition. This comprehensive study from a Gulf Cooperation Council (GCC) country aimed to evaluate the clinical, radiological, and outcome characteristics associated with acute PE.
Methods: This retrospective observational study analyzed data of patients with confirmed acute PE who were admitted to the largest academic tertiary center in the State of Qatar from January 1, 2014, to December 31, 2018. Data on the clinical presentation, radiologic, and echocardiographic findings, as well as outcomes were collected.
Results: A total of 436 patients were diagnosed with acute PE during the study period (male, 53%). Approximately 56% of the patients were < 50 years old at presentation, with a median age of 47 years. In approximately 69% of cases, the PE occurred outside the hospital. The main associated comorbidities were obesity (34.6%), hypertension (29.4%), and diabetes (25%). Immobilization (25.9%) and recent surgery (20.6%) were the most common risk factors. The most frequent presenting symptom was dyspnea (39.5%), and the most frequent signs were tachycardia (49.8%) and tachypnea (45%). Cardiac arrest was the initial presentation in 2.2% of cases. Chest X-ray findings were normal in 41%. On computed tomography pulmonary angiography (CTPA), 41.3% of the patients had segmental PE, 37.1% had central PE, and 64.1% had bilateral PE. The main electrocardiographic (ECG) abnormality was sinus tachycardia (98%). In patients who underwent echocardiography, right ventricular (RV) enlargement was the main echocardiographic finding (36.4%). Low-, intermediate-, and high-risk PE constituted 49.8%, 31.4%, and 18.8% of the cases, respectively. Thrombolysis was prescribed in 8.3% of the total and 24.4% of the high-risk PE cases. Complications of PE and its treatment (from admission up to 6 months post-discharge) included minor bleeding (14%), major bleeding (5%), PE recurrence (4.8%), and chronic thromboembolic pulmonary hypertension (CTEPH) (5%). A total of 15 (3.4%) patients died from PE.
Conclusions: Acute PE can manifest with complex and variable clinical and radiological syndromes. Striking findings in this study are the younger age of acute PE occurrence and the low PE-related mortality rate.
Comparative assessment of the accuracy of ceramic orthodontic brackets to 0.022-inch stainless steel slots in orthodontic patients
Authors: Barbi Wagisha , Rangari Priyadarshini , Chhabada Amarpal Kour , Katiyar Shahshank 
Published: May 2022

Background: Brackets are the passive components that transfer the force to the teeth by elastomeric chains, springs, and the arch wire. The arch wire placement in a bracket that is pre-adjusted is done to construct three-dimensional forces to move the tooth. Aim: The present study was conducted to compare and assess the accuracy of ceramic orthodontic brackets to 0.022-inch stainless steel slots in orthodontic patients. Materials and Methods: The present in-vitro study included a maxillary lateral incisor of the left side where 0.022 MBT American orthodontics (AO) slots as placed with 15 ceramic and 15 stainless steel brackets were placed and divided into 6 groups of 90 subjects. Software analysis was done to assess distal face and base, mesial face and base. Results: For the stainless-steel group, a statistically significant higher slot width was seen for 3M Unitek compared to Ormco and American Orthodontics (AO) slots with p<0.05. Concerning ceramic brackets, higher slot width was seen for American Orthodontics (AO) slots compared to 3M Unitek and Ormco ceramic brackets. This difference was statistically significant with p<0.05. Conclusion: The present study concludes that inaccuracies in dimensions are seen owing to the existing difference between measured values and stated values.
Development of health mix powder to combat anaemia
Authors: Visalakshmi N , Bindu V. 
Published: May 2022

In India, anaemia is a leading cause of death. According to statistics, anaemia is the cause of every maternal fatality. Anaemia is a nutritional illness that affects both adults and children of both sexes, however it is more common in pregnant women and teenage girls and is caused mostly by iron deficiency. Iron and other critical elements required for iron metabolism are abundant in leaves of Moringa oleifera. An increasing finding have found extracts of M. oleifera leaves that aqueous alcohol, or hydro alcohol have a variety of extra activities of biologically, including antiulcer, tissue protective (heart, kidneys, testes, liver, or lungs), radio protective, antioxidant, analgesic, immunomodulatory and antihypertensive properties. The Central Council for Ayurvedic Research has issued preliminary recommendations for standardising commonly used formulas. Standardization of herbal formulations is necessary for determining the quality of pharmaceuticals based on the quantity of active ingredients, as well as physical and chemical parameters. We will briefly discuss many elements of herbal medicinal properties of Moringa oleifera.
Evaluation of interleukin-7 and lipid profile in breast cancer women
Authors: Abbas Maher Hatem , Alsamarai Abdulsalam Tawfeeq Salih 
Published: May 2022

Breast cancer is one of the most common cancerous tumors and one of the main causes after lung cancer that leads to death, and the most common type of breast cancer is adenocarcinoma and is usually detected either during the examination before symptoms appear or after the woman notices the presence of the tumor. Breast cancer is one of the most common diseases in Iraq recently. This study was designed to measure the level of interleukin-7 and its role in cancer, as well as to find out the Level of lipids (cholesterol, triglycerides, and high-density lipoproteins) in breast cancer women and compare them with the control group. The results showed a significant increase( P≤ 0.05) in the level of interleukin-7and high-density lipoprotein cholesterol (357.505±89.921µg\L, 104.383±20.865mg\dl) respectively among patients with breast cancer compared with the control group (150.705±39.559µg\L,114.782±14.139mg\dl) respectively, , and the results showed a significant decrease ( P≤ 0.05) in the level of cholesterol a and triglycerides in patients with breast cancer (104.383±20.865mg\dl , 110.388±18.180mg\dl) respectively compared with the control group(114.782±14.139mg\dl, 138.925±23.178mg\dl) respectively.
EFEITO DA APLICAÇÃO DE ULTRASSOM EM SEMENTES NO DESEMPENHO DE MUDAS HYMENAEA COURBARIL L.
Authors: D'avila Luz Patricia Velásquez , Vela Navarro Zandra Pilar , Santos Isaac de Oliveira , Souza Ronald Antonio Nascimento de , Ribeiro Ítalo Felipe Nogueira , Alves William Ferreira , Maggi Luis Eduardo , Rodriguez Anselmo Fortunato Ruiz , Pereira Wagner Coelho de Alburquerque , Silva Marcelo Castanheira da 
Published: May 2022

A espécie Hymenaea courbaril L., apresenta potencial econômico na comercialização de sua seiva e na indústria madeireira da Amazônia, bem como elevada importância para a medicina popular e construção civil. Sendo assim, este trabalho avaliou o desempenho de plântulas após a aplicação de ultrassom em sementes de Hymenaea courbaril L. No experimento usou-se duas temperaturas de 30 ºC e 35 ºC e quatro grupos com quatro repetições de 25 sementes cada, sendo o grupo controle e três grupos com aplicação de ultrassom na frequência de 3 MHz, intensidade de 2 W/cm² por 2 minutos (T2), 3 minutos (T3) e 4 minutos (T4). Avaliou-se as variáveis de comprimento e massa seca e fresca da parte aérea e radicular. De acordo com os resultados, houve uma redução de massa fresca da raiz e um aumento de massa fresca da parte aérea significativos entre os tratamentos de 3 e 4 minutos relação ao grupo controle. Porém, nenhuma alteração significativa foi percebida para massa seca. Tal fato sugeri alteração do grau de absorção de água, sendo necessários mais estudos empregando outros parâmetros.
Perfectionist Preferentism
Authors: Bruckner Donald W. 
Published: May 2022

AbstractThis paper is about two seemingly inconsistent theories of well-being and how to reconcile them. The first theory is perfectionism, the view that the good of a human is determined by human nature. The second theory is preferentism, the view that the good of a human lies in the satisfaction of her preferences. I begin by sketching the theories and then developing an objection against each from the standpoint of the other. I then develop a version of each theory that is meant to address the objection from the other theory. It turns out that these modified perfectionist and preferentist theories are mutually supporting and co-extensive. They can be combined into a new theory, perfectionist preferentism, which is an independently plausible theory of well-being.
Does Knowledge Intellectualism Have a Gettier Problem?
Authors: Harris Keith Raymond 
Published: May 2022

Abstract
Knowledge intellectualism is the view that knowledge-how requires propositional knowledge. Knowledge intellectualism has a Gettier problem, or so many of its critics allege. The essence of this problem is that knowledge-how is compatible with epistemic luck in a way that ordinary propositional knowledge is not. Hence, knowledge-how can allegedly be had in the absence of knowledge-that, a fact inconsistent with knowledge intellectualism.
This paper develops two responses to this challenge to knowledge intellectualism. First, it is not clear that propositional knowledge is incompatible with the forms of epistemic luck with which knowledge-how is allegedly compatible. Second, existing cases intended to serve as counterexamples to knowledge intellectualism are flawed, and revised versions of these cases no longer elicit the judgments necessary to challenge knowledge intellectualism.
Accuracy Across Doxastic Attitudes: Recent Work on the Accuracy of Belief
Authors: Siscoe Robert Weston 
Published: May 2022

AbstractJames Joyce's article “A Nonpragmatic Vindication of Probabilism” introduced an approach to arguing for credal norms by appealing to the epistemic value of accuracy. The central thought was that credences ought to accurately represent the world, a guiding thought that has gone on to generate an entire research paradigm on the rationality of credences. Recently, a number of epistemologists have begun to apply this same thought to full beliefs, attempting to explain and argue for norms of belief in terms of epistemic value. This paper examines these recent attempts, showing how they interact with work on the accuracy of credences. It then examines how differing judgments about epistemic value give rise to distinct rational requirements for belief, concluding by considering some of the fundamental questions and issues yet to be fully explored.