bluuebunny/crossref_metadata_2025_split huggingface dataset:
KONSTITUSIONALITAS KAIDAH PERSENTASE SELISIH SUARA UNTUK MENGAJUKAN PERMOHONAN PERSELISIHAN HASIL PEMILUKADA DI MK RI
Authors: Antade Aristo 
Published: May 2022

Hak atas persamaan di hadapan hukum serta hak atas upaya hukum yang efektif merupakan hak konstitusional yang melandasi undang-undang. Kedua hak tersebut, menghendaki setiap orang yang ingin memperjuangkan keadilan dan kebenaran harus difasilitas dan tidak boleh dibatasi oleh undang-undang. Pasal 158 ayat (1) dan ayat (2) UU No. 10 Tahun 2016 memuat kaidah persentase selisih suara sebagai syarat untuk dapat mengajukan permohonan perselisihan hasil Pilgub, Pilbup dan Pilkot di Mahkamah Konstitusi Republik Indonesia yang pada dasarnya membatasi pemohon untuk memperjuangkan keadilan dan kebenaran yang ketika proses pemilukada dan penetapan hasil pemilukada tercederai akibat tindakan kejahatan secara terstruktur, sistematis dan masif. Menurut Penulis seharusnya kaidah tersebut tunduk pada dikte hak atas persamaan di hadapan hukum dan hak atas upaya hukum yang efektif.
The right to equality before the law and the right to effective remedies are constitutional rights on which the law is based. Both of these rights require that everyone who wants to fight for justice and truth must be facilitated and must not be limited by law. Article 158 paragraph (1) and paragraph (2) of Law No. 10 of 2016 contain the principle of percentage difference in votes as a condition to be eligible to submit disputes Constitional Court of the Republic of Indonesiaon the results of the election of governor, regent, and major (local election). The principle on the provisions basically hamper the applicants whose rights are violated by structured, systematic and massive acts during the process of local election to fight for justice and truth concerning on the decision of the election result. According to the author, the rule should be subject to the dictation of the right to equality before the law and the right to effective legal remedies.
PENETAPAN TERSANGKA SEBAGAI OBJEK PRAPERADILAN DALAM PUTUSAN MK NO. 21/PUU/XII/2014 SEBAGAI PEMENUHAN HAM DAN TERCAPAINYA SISTEM PERADILAN PIDANA TERPADU
Authors: Teslatu Leo Christy Menoha 
Published: May 2022

Putusan Mahkamah Konstitusi No. 21/PUU-XII/2014 menambahkan objek praperadilan dalam ketentuan Pasal 77 KUHAP, sehingga objek praperadilan diperluas, yaitu termasuk sah atau tidaknya penetapan tersangka, sah atau tidaknya penggeledahan dan sah atau tidaknya penyitaan. Akan tetapi yang menjadi persoalan adalah dengan adanya perluasan objek praperadilan tersebut apakah mencerminkan keadilan, kepastian serta kemanfaatan atau malah sebaliknya mencerminkan ketidakadilan, ketidakpastian serta tidak bermanfaat. Oleh karena itu dalam penelitian ini, penulis akan menganalisis mengapa Mahkamah Konstitusi memutuskan penetapan tersangka sebagai objek praperadilan. Alasan diputuskannya penetapan tersangka sebagai salah satu objek untuk mengajukan praperadilan oleh Mahkamah Konstitusi adalah (1) untuk melindungi setiap warga negara terhadap penyalahgunaan kekuasaan oleh lembaga negara yang dapat merugikan hak setiap individu warga negara, (2) bentuk pengawasan dan mekanisme kontrol terhadap proses penegakan hukum yang terkait erat dengan jaminan perlindungan hak asasi manusia, (3) penyeimbang dalam hal adanya benturan antara hak-hak individu dengan kekuasaan negara. Penelitian ini adalah penelitian hukum normatif.
Decision of the Constitutional Court No. 21/PUU-XII/2014 has expanded the pretrial object regulated in the provisions of Article 77 of the Criminal Procedure Code. The pretrial object has expanded to the validity of the suspects, the search, and the confiscation. However, the problem arises with the expansion of the pretrial object whether it reflects justice, certainty and usefulness or even, on the contrary, reflects injustice, uncertainty and not useful. Therefore, the author will analyze the legal reasoning of the Constitutional Court which ruled the determination of the suspect as a pretrial object. It is found that the reasons are: (1) to protect every citizen from abuse of power by state institutions that can harm the rights of each individual citizen, (2) to supervise and control mechanisms for the process of law enforcement which is closely related to guaranteeing the protection of human rights, (3) to balance between individual rights and state power. This research is a normative legal research.
Classifier Spot Count Optimization of Automated Fluorescent Slide Scanning System
Authors: Lucian Zastko , Martin Bereta , Jaroslav Timko , Igor Belyaev 
Published: May 2022

Abstract

Purpose: Ionizing radiation induced foci (IRIF) known also as DNA repair foci represent the most sensitive endpoint for assessing DNA double strand breaks (DSB). IRIF are usually visualized and enumerated with the aid of fluorescence microscopy using antibodies to γH2AX and 53BP1. Although several approaches and software packages were developed for the quantification of IRIF, not one of them was commonly accepted and inter-laboratory variability in the outputs was reported. In this study, the sensitization of Metafer software to counting also small appearing IRIF was validated.

Materials and Methods: Human lymphocytes were γ-irradiated at a dose of 2 Gy. The cells were fixed at 0.5, 1, 2, and 18 hours post-irradiation, permeabilized and IRIF were immunostained using appropriate antibodies. Cell images were acquired with the automatic Metafer system. Radiation-induced γH2AX and 53BP1 foci were enumerated using either manual counting (JCountPro program) or the Metafer software (after its classifier optimization has been done) and compared. The statistical analysis was performed using One-way ANOVA.

Results: The enumeration of 53BP1, γH2AX foci manually by JCountPro did not statistically significantly differ from the automatic one performed with the optimized Metafer classifier. A detailed step-by-step protocol of this successful optimization is described in this study.

Conclusions: We concluded that the Metafer software after the optimization was efficient in objectively enumerating IRIF, having a potential for usage in clinics and molecular epidemiology.
Association of Genetic Variability in Selected Genes with Platelet Hyperaggregability and Arterial Thrombosis
Authors: Monika Brunclikova , Jela Ivankova , Maria Skerenova , Tomas Simurda , Lucia Stanciakova , Ingrid Skornova , Miroslava Sterankova , Jana Zolkova , Miroslava Dobrotova , Pavol Holly , Peter Kubisz , Jan Stasko 
Published: May 2022

Abstract

Introduction: Inherited platelet hyperaggregability, so called “Sticky platelet syndrome” (SPS), is a prothrombotic platelet disorder. The syndrome contributes more often to arterial than venous thrombosis. The most common localization of arterial occlusion involves cerebral or coronary arteries. However, SPS may also lead to thrombosis in the atypical sites of the circulation. This qualitative platelet alteration causes platelet hyperaggregability after a very low concentration of platelet inducers – adenosine diphosphate (ADP) and/or epinephrine (EPI). The precise genetic background of the syndrome has not been defined. In the present study we aimed to determine the association between selected single nucleotide polymorphisms (SNPs) within genes for platelet endothelial aggregation receptor 1 (PEAR1) and murine retrovirus integration site 1 (MRVI1) and the risk for arterial thrombosis in patients with SPS. The products of these selected genes play an important role in platelet aggregation.

Patients and methods: We examined 69 patients with SPS and a history of arterial thrombosis and 69 healthy blood donors who served as controls. SPS was confirmed by a light transmission aggregometry (LTA) according to the method and criteria described by Mammen and Bick. We assessed two SNPs within PEAR1 gene (rs12041331, rs1256888) and two SNPs within MRVI1 gene (rs1874445, rs7940646).

Results: Selected PEAR1 and MRVI1 polymorphisms seem not to be a risk factor for the development of SPS as the syndrome with an arterial thrombosis phenotype. However, in the subgroup of SPS1 patients there was found a decreased frequency of the minor A allele of SNP rs12041331 in PEAR1 gene (borderline p value, p=0.061) that can be hypothesized as protective against arterial thrombosis. In the same SPS1 subgroup the haplotype TA in PEAR1 gene also showed a decreased frequency with a borderline insignificance (p=0.056). We can theorize also about its protective role in SPS1 patients. We did not confirm the protective effect of polymorphism (T/T of rs 12566888) in PEAR1 against arterial thrombosis in SPS patients and SPS subgroups.

Conclusion: Our results support the idea that examined genetic variability of the selected SNPs in PEAR1 and MRVI1 genes is not associated with platelet hyperaggregability manifested as arterial thrombosis. The possible protective role of the minor A allele of SNP rs12041331 as well as a role of haplotype TA in PEAR1 gene related to the arterial thrombosis found in the subgroup of SPS1 patients needs to be verified in further research.
The occurrence of fungi on the commercial dietary supplements based on the milk thistle (Silybum marianum (L.) Gaertn.) available on Polish market
Authors: Rosińska Agnieszka 
Published: May 2022

Summary

Introduction: Milk thistle (Silybum marianum (L.) Gaertn.) is an important medicinal plant, its achenes contain a silymarin, which has a regenerating and stabilizing effect on liver cells. The milk thistle based dietary supplements are among the best-selling plant pharmaceuticals in the US and the UE.

Objective: The goal of the experiment was to determine which – if any – fungi contaminated either the whole or ground milk thistle achenes, available on the Polish market.

Methods: The mycological analyses were performed on 200 achenes, using deep-freeze blotter method. Ground material was assessed using agar test method. For each sample, 10 Petri dishes were used. The material was applied in five places per one Petri dish, with a micro scoop laboratory spatula. Then, Petri dishes with achenes and ground material were incubated at 20°C under alternating cycles of 12 h NUV light and 12 h darkness. The identification of fungi was performed using stereo microscope and compound microscope, if necessary.

Results: The milk thistle achenes were infested with following fungi: Alternaria alternata, Alternaria sp., Aspergillus flavus, Aspergillus spp., Bipolaris sp., Cladosporium spp., Epicoccum nigrum, Fusarium spp., Melanospora simplex, Mucor spp., Penicillium spp., Phoma sp., Rhizopus stolonifer, Sarocladium strictum, Stemphylium botryosum, Trichothecium roseum, Ulocladium consortiale and Verticillium sp. Among them A. alternata predominated. Whereas, milled milk thistle achenes were occupied by Aspergillus flavus, A. niger, Aspergillus spp., Fusarium sp., Mortierella spp., Mucor spp., Penicillium spp. and R. stolonifer.

Conclusion: Considering the significant fungal contamination of milk thistle achenes-based dietary supplements, it seems reasonable to introduce a system of achene control due to possible microbiological contamination.
The Position of Romania within the European Union Budget in the Context of the Crisis caused by the COVID-19 Pandemic
Authors: Drăgoi Violeta Elena , Preda Larisa Elena 
Published: May 2022

Abstract
The study analyses the main predominant factors affecting the revenues and expenditures of the EU budget for 2020-2027 and the position of Romania as an EU Member State on flows to EU challenges: flow of problems, flow of challenges and flows of Member States’ interests.
БАРОКОВА ОБРАЗНІСТЬ В КОНТЕКСТІ ДУХОВНИХ ПІСЕНЬ ПОЧАЇВСЬКОГО БОГОГЛАСНИКА
Authors: Медведик Галина 
Published: May 2022

У статті розглянуто окремі аспекти змісту духовних пісень Почаївського Богогласника 1790–1791 рр. у контексті барокової образності. Виявлено, що в духовних піснях збірника використовується характерна тематика найпоширенішої літератури того часу, зокрема, греко-візантійської сакральної монодії, старозавітньої і апокрифічної літератури. На цій основі поєднуються релігійні мотиви, що є виразним свідченням тяглості літургійно-мистецької традиції у межах найважливіших ділянок суспільного життя українського етносу.
Досліджується значення духовних пісень у контексті забезпечення свідомої участі мирянина у літургійному дійстві. Вивляються образні та музично-інтонаційні засоби і лексичні паралелі гимнографічних піснеспівів та духовних пісень. Це підкреслює актуальність півчої літургійної практики барокової доби і в наступні періоди. У такий спосіб в українській культурі поєдналися традиції обрядових богослужінь і західноєвропейського католицько-протестантського досвіду духовного співу. В цьому контексті Почаївський Богогласник є свідченням еволюції унікальної співочої спадщини з великим потенціалом соціокультурного розвитку.
PERANCANGAN DAN PEMBUATAN REKAM MEDIS ELEKTRONIK BERBASIS WEB DENGAN MEMANFAATKAN QR CODE DI PUSKESMAS KARYA MAJU KABUPATEN MUSI BANYUASIN
Authors: Meirina Detty Artin , Farlinda Sustin , Erawantini Feby , Yunus Muhammad 
Published: May 2022

Teknologi informasi memberi banyak kemudahan dalam proses manajemen serta dapat mengolah data dan informasi kemudian mendistribusikannya secara lebih mudah, fleksibel, dan akurat. Teknologi informasi juga diadopsi bidang kesehatan dengan tujuan dapat memproduksi suatu informasi dalam pengambilan keputusan yang berkaitan dengan tata laksana pelayanan kesehatan serta dalam rangka mendukung penyelenggaraan pembangunan kesehatan yang dikelola oleh sistem informasi kesehatan. Sumber data dan informasi sistem informasi kesehatan diperoleh dari dokumen rekam medis maka dokumen rekam medis harus memiliki kualitas informasi yang baik. Permasalahan yang ditemukan di Puskesmas Karya Maju, yaitu pencatatan dokumen rekam medis yang masih manual dan terkadang petugas kesulitan ketika mencari kembali dokumen rekam medis karena petugas keliru ketika meletakkan kembali dokumen rekam medis tersebut ke tempat semula yang dapat mengakibatkan kurangnya kualitas informasi data yang dihasilkan. Penelitian ini bertujuan untuk merancang dan membuat rekam medis elektronik berbasis web dengan memanfaatkan QR Code yang diharapkan dapat mengatasi permasalahan yang ditimbulkan dari pencatatan dan pengolahan rekam medis yang masih manual. Jenis penelitian yang digunakan, yaitu penelitian kualitatif dengan metode pembuatan sistem Waterfall yang terdiri dari tahapan analisis, desain, pengkodean, dan pengujian. Teknik pengumpulan data menggunakan wawancara, dokumentasi, dan observasi. Hasil dari penelitian ini adalah rekam medis elektronik berbasis web yang dilengkapi dengan QR Code dengan tujuan ketika pasien datang kembali untuk berobat maka pasien tidak perlu membawa KIB. Cukup membawa smartphone yang sudah login dengan akun pasien yang telah didaftarkan sebelumnya dan petugas akan menscan QR Code tersebut untuk mencari identitas dan rekam medis pasien.

Kata Kunci: Rekam Medis Elektronik, QR Code, Waterfall.
Antibacterial Activity of Calendula Officinalis Flowers In Vitro
Authors: Hamad M.N. , Mohammed H.J. , Merdaw M.A. 
Published: May 2022

Flower samples of Calendula officinalis were collected from the gardens of the college of Pharmacy in Baghdad city to examine their antibacterial activity .The effect of ethanol crude extract of petals and reproductive parts of flowers in different concentrations were obtained and bioassayed in vitro for its bioactivity to inhibit the growth of eight types of bacteria .The extracts of petals part were clearly superior for all bacteria especially the bacteria Pseudomonas aeruginosa (inhibition zone was 25mm in the concentration 100mg/ml) from gram negative bacteria, and Staphylococcus aureus (inhibition zone was 14mm in the concentration 50mg/ml) from gram positive bacteria, while the extracts of reproductive parts were less effective than petals part. These results confirm the antibacterial activity of Calendula officinalis flowers and support the traditional use of the plant in the therapy of bacterial infection
In vivo study of cardioprotective effect of bay leaf (Syzygium polyanthum) extract
Authors: Ikhtiari Refi , Sari Laura Kartika , Nasution Ali Napiah , Ginting Chrismis Novalinda , Handoko Erwin , Lister I Nyoman Ehrich 
Published: May 2022

Background: The excessive use of chemotherapy drugs such as doxorubicin might induce cardiovascular diseases. Heart-specific biomarker enzymes such as LDH and BNP indicated the early signs of cardiotoxicity. However, there is no report on the effect of bay leaf on LDH and BNP nor its bioactive compounds and histopathology analysis.Objective: This study aims to determine the cardioprotective effect of Ethanol Extract of Bay Leaf (EEBL) based on phytochemical analysis, LDH and BNP levels, and cardiac histology of rats administered with doxorubicin.Methods: About 24 Wistar rats were divided into six groups treated with 100 mg/kg BW, 300 mg/kg BW, and 500 mg/kg BW of EEBL with CMC-Na 0.5 %, vitamin E, and doxorubicin. Preconditioning was 14 days, followed by 21 days of intraperitoneal administration. LDH and BNP parameters were measured on days 1st, 7th, 14th, and 20th. Histology analysis was conducted on day 21st.Results: Dark green EEBL showed sufficient physical quality and properties for practical application in pharmacy. EEBL has significantly affected LDH, BNP, and cardio recovery dose-dependent. The most effective doses were observed at 500 mg/kg BW, and its performance is not statistically different from those of the commercial vitamin E. The histopathological images revealed significant improvements in interstitial edema, wavy fibers, hemorrhage, intracellular vacuole, and inflammatory cell infiltration. Here we report six bioactive compounds obtained from EEBL have cardioprotective effects; Neophytadiene, squalane, phytol, methyl palmitate, stigmasterol, and 9,12-Octadecanoic acid methyl ester.Conclusion: This study has shown the promising potential of bay leaf extract as a cardioprotector with sufficient quality pharmacological standards.
ANALISIS KEMAMPUAN KOMUNIKASI MATEMATIS SISWA SMP PADA MATERI SEGI EMPAT DITINJAU DARI GENDER
Authors: Tarantein Marselia Hellena , Ayal Carolina Selfisina , Moma La 
Published: May 2022

Kemampuan komunikasi matematis adalah kemampuan menyampaikan gagasan atau ide matematika, baik secara lisan maupun tulisan dalam menyajikan suatu persoalan atau masalah ke dalam model matematika berupa persamaan, grafik, diagram, ide, gagasan, tabel, dan pernyataan matematika. Penelitian ini bertujuan untuk mendeskripsikan kemampuan komunikasi matematis siswa kelas VII SMP Kristen YPKPM Ambon yang ditinjau dari perbedaan gender. Jenis penelitian yang digunakan adalah penelitian kualitatif. Penelitian dilakukan di SMP Kristen YPKPM Ambon dengan jumlah subjek penelitan 20 orang dari kelas VIII-4 dan subjek yang dipilih untuk diwawancarai sebanyak 6 siswa yang terdiri dari 3 siswa laki-laki dan 3 siswa perempuan, penetapan subjek dalam penelitian ini dilakukan dengan pertimbangan siswa yang dapat berkomunikasi dengan baik dan pertimbangan guru mata pelajaran. Soal segiempat diberikan untuk melihat kemampuan komunikasi matematis siswa dengan 3 indikator yaitu indikator kemampuan menulis (Written text), indikator kemampuan menggambar (Drawing), dan indikator kemampuan ekspresi matematika (Mathematical Expression). Berdasarkan hasil tes kemampuan komunikasi matematis siswa terdapat 1 siswa perempuan yang memenuhi tiga indikator kemampuan komunikasi matematis, 1 siswa perempuan dan 1 siswa laki-laki yang memenuhi dua indikator kemampuan komunikasi matematis yaitu indikator kemampuan menulis (Written text) dan indikator eksperi matematika (Mathematical Expression), 1 siswa laki-laki yang memenuhi satu indikator kemampuan komunikasi matematis yaitu indikator kemampuan menulis (Written text), serta 2 siswa terdiri dari 1 perempuan dan 1 siswa laki-laki tidak memenuhi tiga indikator kemampuan komunikasi matematis
The Effect of Promotion on Purchase Decision at Cafe Praja Bintaro, South Tangerang
Authors: Setiawan Christin , Octarina Dian , Pangosta Jeefrey Rabito 
Published: May 2022

This study aims to determine the effect of promotion on purchasing decisions. This research is a quantitative descriptive study with a simple regression analysis method. The sampling technique used is accidental sampling. Consumers who happen to meet with researchers can be used as samples and are feasible as data sources. The population in this study were all consumers of Café Praja Bintaro, South Tangerang, a sample of 100 respondents. The results showed that promotion had a significant effect on purchasing decisions. Promotions are carried out offline and can also be done online, such as doing promotions on Instagram, Facebook, and Twitter. Promotion is carried out by the company and employees and can also be done by consumers; Therefore, Café Praja Bintaro South Tangerang is always expected to maintain product quality and service quality.
Keywords: Promotion, Purchase Decision
МОДЕЛЬ ДОСТАВКИ ЦИФРОВОГО НАВЧАЛЬНОГО КОНТЕНТУ В УМОВАХ ВІДКРИТОЇ УНІВЕРСИТЕТСЬКОЇ ОСВІТИ
Authors: Глазунова Олена , Волошина Тетяна , Корольчук Валентина , Мокрієв Максим , Кузьмінська Олена 
Published: May 2022

Формулювання проблеми. Зважаючи на виклики, з якими стикається сучасне суспільство, зокрема, пандемії, війни тощо, та освітні тенденції, пов’язані з персоналізованою та відкритою освітою, важливим стає питання забезпечення індивідуальних освітніх потреб студентів, які можливо задовольнити шляхом створення персоніфікованого навчального контенту та відкритого доступу до нього. Проблема полягає у тому, що у закладах вищої освіти відсутній відповідний рівень готовності переходу на принципи відкритості та забезпечення доставки навчального контенту здобувачам в умовах відкритої університетської освіти.
Матеріали і методи. З метою вирішення поставленої проблеми було застосовано методи аналізу, класифікації та систематизації наукових джерел з проблеми дослідження, методи моделювання для розробки моделі доставки навчального контенту в умовах відкритої освіти. Дослідження виконано в межах науково-дослідної роботи «Створення моделі гібридного веборієнтованого середовища доставки навчального контенту в умовах відкритої університетської освіти» за договором №110/11-пр-2020.
Результати. У дослідженні проведено аналіз варіантів доставки різнотипного навчального контенту в умовах відкритої університетської освіти. Обґрунтовано та розроблено модель доставки навчального контенту в умовах відкритої університетської освіти, що включає: концептуальний, функціональний, технологічний, організаційний, методичний та діагностичний блоки. На основі запропонованих блоків визначено педагогічні умови для ефективної доставки навчального контенту.
Висновки. Враховуючи тенденції інформатизації освітнього простору та відкритості університетської освіти, дотримуючись принципів відкритої, дистанційної та неформальної освіти, результатом реалізації запропонованої моделі передбачаємо ефективне забезпечення доставки навчального контенту для різних форм та видів навчальної діяльності.