bluuebunny/crossref_metadata_2025_split huggingface dataset:
P10-02 Barriers to use of the internet as an alternative delivery channel for an evidence-based fall-prevention intervention for older adults
Authors: Jones Dina , Robinson Maura , Selfe Terry Kit , Barnes Lucinda , Wen Sijin , Shawley-Brzoska Samantha , Myers Douglas , Wilcox Sara 
Published: August 2022

Abstract

Issue/problem
Physical activity (PA) can prevent falls, a leading cause of death globally. Alternative delivery channels may increase the “reach” of interventions into older adult populations in areas which lack trained instructors. Using technology is one alternative to traditional, face-to-face group classes where instructors and participants are in the same room. We delivered a PA program via the Internet for older adults in rural West Virginia (USA). This alternative could help other countries reach more older adults and reduce falls.

Description of the problem
Tai Ji Quan: Moving for Better Balance® (TJQMBB) is an evidence-based intervention for older adults that reduces falls. Adults, ≥ 55 years, attended free, 1-hour tele-TJQMBB sessions, twice weekly, for 16 weeks at 5 remote community sites (3 urban, 2 rural). Trained instructors (new to TJQMBB) led 6 classes from a classroom for participants at remote sites. Instructors/sites used minicomputer, web camera, microphone, and television(s) for live, 2-way verbal/audio exchange. A CPR-certified person was present with participants. This project identified barriers to implementing tele-TJQMBB. Data on barriers were collected from instructors' class logs and summarized.

Results
Fifty-two adults (81% female, mean age 70) attended 23 (median) of 32 sessions. Barriers that caused session cancelations included: participant vacations/unavailability (n = 7), inclement weather (n = 4), technical issues (n = 2), no CPR person (n = 1), classroom not available (n = 1), site closed for state holiday (n = 1), competing event at site (n = 1), and ill instructor (n = 1). Technical barriers during sessions included interruptions/lack of audio, video freezing, and Wi-Fi/Internet connectivity problems. Two participants did not like videoconferencing.

Lessons
Tele-TJQMBB may be easier to teach with instructors who have already taught the program in-person. Selecting instructors/sites that are comfortable with technology may reduce technological barriers. Some older adults may still prefer face-to-face classes. Most cancelations were due to reasons normally encountered in face-to-face classes. Use of technology added new barriers that will need addressed for future classes.

Main messages
Technology reached older adults in areas with no instructors. We think that this is the first time a live, evidence-based, group PA intervention was delivered using this method which could be a model for reaching older adults globally.
P10-11 The effect of a pedometer-based intervention across two years, in people with type 2 diabetes and prediabetes - a compositional data analysis
Authors: Larsson Kristina , Von Rosen Philip , Rossen Jenny , Johansson Unn-Britt , Hagströmer Maria 
Published: August 2022

Abstract

Background
For people with prediabetes and type 2 diabetes it is important to be regularly physical active. Increasing and maintaining physical activity (PA) can be challenging. The aim of this study was to evaluate the effects of a pedometer-based intervention on PA, with a compositional data analysis (CoDA) approach, in individuals with prediabetes or type 2 diabetes.

Methods
Longitudinal data on 188 participants with prediabetes and type 2 diabetes (40% female, mean age = 64.1 years) from a three-armed randomized controlled trail, the Sophia Step Study, was used. The three groups were a multi?component group (self?monitoring of steps with a pedometer, together with group (12 occasions) and individual counselling (10 occasions)), a single?component group (self?monitoring of steps with a pedometer, without counselling) and a standard care group. PA (moderate-to-vigorous PA (MVPA), light-intensity PA (LIPA) and sedentary behaviour (SB)) during the awake time were measured with ActiGraph GT1M accelerometer at baseline, 6, 12, 18 and 24 months. Relative time in MVPA, LIPA and SB for each participant at each measurement point was calculated by using the CoDA approach. Linear mixed models were used to evaluate the intervention effect between the three groups on the relative time in MVPA, LIPA and SB over the two-year period.

Results
In total, 41% had ≤30 min MVPA at baseline. Significant group by time interactions were found for the multi-component group and the standard care group for the relative time in MVPA, at 6, 18 and 24 months. Differences in predicted group means between the groups were 1.2% at 6 months, 1.3% at 18 months and 0.9% at 24 months. Significant group by time interactions were also found for the single-component group and the standard care group for the relative time in MVPA at 24 months, with a difference in predicted group means of 0.8%. No significant interactions for LIPA or SB were found.

Conclusions
The multi-component group and the single-component component group maintained their relative time in MVPA, while the standard care group decreased their relative time in MVPA over the two-year period. This indicate that the Sophia Step Study intervention can prevent a decrease in MVPA in people with prediabetes and type 2 diabetes.
P10-12 DIPPAO: digital-based intervention promoting physical activity among obese people
Authors: Mazeas Alexandre , Chalabaev Aïna , Blond Marine , Duclos Martine 
Published: August 2022

Abstract
Despite the accumulation of scientific evidence supporting the benefits of physical activity, the general population remains insufficiently active and this situation is even worsened for some specific populations such as obese people (Barker et al., 2019). It is therefore becoming urgent to develop interventions that can effectively change individuals' behavior. In this context, “e-health” interventions and gamification appear to be a particularly promising avenue to improve physical activity and reduce attrition rates of current programs.
This study protocol aims to present a randomized, two-arm intervention design that will examine the efficacy of a digital intervention based on play and teamwork for an obese sample. Fifty patients will be recruited at the hospital of Clermont-Ferrand, France and randomized into two groups: the experimental group will receive digital supervised sessions of PA in videoconference and a gamification of PA through a mobile app and will be compared to an active control group representing the traditional care program (supervised physical activity three times per week during three months). Informed by the tenets of the social identity approach and built around behavior change techniques, implemented via the principles of gamification, this three-month intervention has the objective to improve physical activity adherence. Objective and self-reported PA, quality of live, physical condition and psychological variables like motivation or perceived discrimination will be assessed before, at the end of the intervention and then at the issue of a 6-month follow up in order to evaluate the long-term effect of the intervention. We make the assumption that the intervention will be efficient by the development of an intrinsic motivation through the process of gamification on the one hand. On the other hand, through the in-group collaboration with other people who share the same stigmatized criteria that will help participants to overcome weight stigmas, acting generally as physical activity barriers.
This poster presentation will introduce the conception of the intervention, the experimental design and proposed evaluation of the trial. If the effectiveness of this intervention is confirmed, its implementation in the health circuit could reduce the costs and constraints associated to face-to-face support.
Translocating Humour to Seventeenth-Century England: The Comic Afterlife of Spanish Drama
Authors: Riera Jorge Braga 
Published: August 2022

Abstract
The term ‘Golden Age’ broadly describes a period (the mid-sixteenth to late-seventeenth centuries) of great literary flowering in Spain, above all in theatre, where honour, love and humour emerged as recurring motifs. Unsurprisingly, Caroline and even more so Restoration England took an interest in the genre and imported several Spanish comedias, which made a modest but essential qualitative contribution to the London stage during this age. This essay centres on the purposes and limitations of humour in Spanish Golden Age drama, and on the extent to which the linguistic and semiotic aspects linked to comic performance were successfully carried over into the seventeenth-century English versions. By examining a corpus of performance-oriented plays in translation, I seek to illustrate the way in which contemporary British translators rendered comicality, studying how it was maintained, modified or distorted in the process, and taking into account the particular landscape proper to drama-translation practice and its degree of acceptance in the recipient culture. The dramatic areas in which comic devices function – plot, character, thought, diction, music and spectacle – are given special attention. The results reveal how practitioners may have obliterated the so-called Spanish flavour of the original comedy in an attempt to seek deliberately audience-friendly solutions, so as to fall in line with the expectations of the target theatrical context.
How Statues Speak
Authors: Friedell David , Liao Shen-yi 
Published: August 2022

Abstract
We apply a familiar distinction from philosophy of language to a class of material artifacts that are sometimes said to “speak”: statues. By distinguishing how statues speak at the locutionary level versus at the illocutionary level, or what they say versus what they do, we obtain the resource for addressing two topics. First, we can explain what makes statues distinct from street art. Second, we can explain why it is mistaken to criticize—or to defend—the continuing presence of statues based only on what they represent. Both explanations are driven by the same core idea: the significance of statues arises primarily from what they do and not what they say.
HIV stigma limits the effectiveness of PMTCT in Guinea: the ANRS 12344-DIAVINA study
Authors: Breton Guillaume , Diallo Oumou Hawa , Cissé Mohamed , Diallo Oumou Hawa , Diallo Néné Aissatou , Soumaoro Sény Agnès , Camara Yalikhatou , Montoyo Alice , Rouzioux Christine , Koita Youssouf , Peytavin Gilles , Tubiana Roland , Frange Pierre ,   the ANRS 12344-DIAVINA study group, Basla Joséphine , Becquet Renaud , Breton Guillaume , Camara Yalikatou , Cissé Mohamed , D'Ortenzio Eric , Dia Hasminou , Diallo Alpha , Diallo Néné Aissatou , Diallo Oumou Hawa , Diallo Omou Hawa , Diallo Penda , Dollfus Catherine , Frange Pierre , Koita Youssouf , Leroy Valériane , Gardiennet Elise , Montoyo Alice , Oy Kolié , Peytavin Gilles , Rouzioux Christine , Agnés Soumaoro Sény , Sy Telly , Sylla Mariam , Teijokem Mathurin , Tubiana Roland 
Published: August 2022

Abstract

Background
Nearly half of HIV-infected children worldwide are born in West and Central African countries where access to prevention of mother-to-child transmission of HIV (PMTCT) programmes is still limited. WHO recommends reinforced antiretroviral prophylaxis for infants at high risk of mother-to-child transmission of HIV (MTCT) but its implementation needs further investigation in the field.

Methods
The prospective ANRS 12344-DIAVINA study evaluated the feasibility of a strategy combining early infant diagnosis (EID) and reinforced antiretroviral prophylaxis in high-risk infants as identified by interviews with mothers at Ignace Deen Hospital, Conakry, Guinea.

Results
6493 women were admitted for delivery, 6141 (94.6%) accepted HIV testing and 114 (1.9%) were HIV positive. Among these, 51 high-risk women and their 56 infants were included. At birth, a blood sample was collected for infant EID and reinforced antiretroviral prophylaxis was initiated in 48/56 infants (86%, 95% CI 77%–95%). Iron supplementation was given to 35% of infants for non-severe anaemia. Retrospective measurement of maternal plasma viral load (pVL) at delivery revealed that 52% of women had pVL &lt; 400 copies/mL attributable to undisclosed HIV status and/or antiretroviral intake. Undisclosed HIV status was associated with self-stigmatization (85% versus 44%, P = 0.02). Based on the results of maternal pVL at delivery, ‘real’ high-risk infants were more frequently lost to follow-up (44% versus 8%, P &lt; 0.01) in comparison with low-risk infants, and this was associated with mothers’ stigmatization (69% versus 31%, P &lt; 0.01).

Conclusions
Reinforced antiretroviral prophylaxis and EID at birth are widely feasible. However, mothers’ self-disclosure of HIV status and antiretroviral intake do not allow adequate evaluation of MTCT risk, which argues for maternal pVL measurement near delivery. Furthermore, actions against stigmatization are crucial to improve PMTCT.
Faecal carriage of multidrug-resistant bacteria and associated risk factors: results from a point prevalence study
Authors: Grohs Patrick , Vilfaillot Aurélie , Zahar Jean Ralph , Barbut Frédéric , Frange Pierre , Casetta Anne , Moulin Véronique , Lawrence Christine , Baune Patricia , Bourgeois Cléo , Bouffier Axel , Laussucq Claudine , Sienzonit Lydia , Picard Simon , Podglajen Isabelle , Kassis-Chikhani Najiby 
Published: August 2022

Abstract

Objectives
Since 2003, incidences of carbapenemase-producing Gram-negative bacilli (CP-GNB) and vancomycin-resistant Enterococcus faecium (VRE) have steadily increased in France. We therefore conducted a point prevalence study to estimate carriage rates of CP-GNB, VRE and ESBL-producing Enterobacterales (ESBL-PE) and associated risk factors.

Methods
Between September 2019 and January 2020, all inpatients hospitalized on a given day in 11 teaching hospitals in the Paris urban area were eligible. Patient interviews and rectal swab screening results were recorded by dedicated nurses. The swabs were plated onto selective chromogenic media and processed using the GeneXpert® system.

Results
Of 2396 patients, 364 (15.2%) yielded at least one multiresistant bacterial isolate, including 29 CP-GNB carriers (1.2%), 13 VRE carriers (0.5%) and 338 ESBL-PE carriers (14%). In 15 patients (4.4% of ESBL-PE carriers and 36.6% of CP-GNB/VRE carriers), concomitant CP-GNB/VRE and ESBL-PE carriage was observed. In 7/29 CP-GNB and 7/13 VRE carriers, carbapenemase production and vanA in the screening samples was only detected with Xpert® tests. The OXA-48 gene was predominant in 13/34 CP-GNB isolates from 29 carriers. From the 338 ESBL-PE carriers, 372 isolates were recovered, mainly Escherichia coli (61.2%). Among 379 children, 1.1% carried a CP-GNB/VRE strain, and 12.4% carried an ESBL strain. Previous hospitalization outside mainland France, previous antimicrobial treatment and previous ESBL-PE carriage were the main risk factors associated with CP-GNB and/or VRE carriage.

Conclusions
The low CP-GNB and VRE prevalence likely reflects the French policy to limit intrahospital spread of CP-GNB and VRE strains.
Outcomes Following Use of Negative-Pressure Wound Therapy Over Autologous Meshed and Non-Meshed Skin Grafts
Authors: Sweitzer Keith , Tomtschik Julia , Butterfield James , Bell Derek 
Published: August 2022

Abstract
Negative-pressure wound therapy (NPWT) over split thickness skin grafts can control exudate, decrease infection rates, and improve revascularization. However, no study specifically addresses differences in outcomes between meshed/perforated and non-meshed autologous skin grafts dressed with NPWT. Through retrospective chart review, patients undergoing autologous split thickness skin grafting with a NPWT dressing for any burn injury over a 10-month period were identified. Data on etiology, graft take, meshed/perforated or non-meshed graft, graft size, and seroma/hematoma incidence were collected. Our study included 123 patients who had STSG with NPWT and consisted of 57% males, 57% Caucasian, and an average age of 41. Burn injury etiologies consisted of scald (55%), chemical (25%), flame (15%), and contact (5%). Average 2nd degree TBSA in our cohort was 2.34%, 3rd degree TBSA 4.50%, and total TBSA 5.35%. 66.7% of patients received non-meshed grafts, and these patients had an average graft area of 76.5 cm2. 33.3% of patients received meshed grafts, with an average graft area of 163.5 cm2. Non-meshed burn grafts were significantly smaller than meshed grafts (P = .04). There was 100% graft take and 0% seroma/hematoma formation in all patients. Data was analyzed using an unpaired student’s T test and ANOVA testing. There were no statistically significant differences in patient demographics, or burn etiology. There exist many options for dressings after repair of burn injuries, each with its own unique advantages. There were, however, no differences in graft take or incidence of seroma/hematoma formation using a NPWT dressing over autologous meshed grafts vs non-meshed grafts. Our data shows that NPWT use as a bolster dressing is safe and efficacious overlying meshed skin grafts and non-meshed grafts.
Bone Lesions Detected on Breast MRI: Clinical Outcomes and Features Associated With Metastatic Breast Cancer
Authors: Corines Marina J , Coffey Kristen , Dou Eda , Lobaugh Stephanie , Zheng Junting , Hwang Sinchun , Feigin Kimberly 
Published: August 2022

Abstract

Objective
To determine prevalence and frequency of malignancy among bone lesions detected on breast MRI and to identify clinical and imaging features associated with bone metastases from breast cancer (BC), as bone lesions are suboptimally evaluated on breast imaging protocols and can present a diagnostic challenge.

Methods
This IRB-approved retrospective review of breast MRIs performed from June 2009 to June 2018 identified patients with bone lesions. Demographic, clinical, and MRI features were reviewed. Clinical outcome of bone lesions was determined based on pathology and/or additional diagnostic imaging. All benign lesions had ≥2 years of imaging follow-up. Statistics were computed using Fisher exact and Wilcoxon rank sum tests.

Results
Among all patients with breast MRI, 1.2% (340/29 461) had bone lesions. Of these, 224 were confirmed benign or metastatic BC by pathology or imaging follow-up, with 70.1% (157/224) benign and 29.9% (67/224) metastatic. Bone metastases were associated with BC history (P &lt; 0.001), with metastases occurring in 58.2% (53/91) of patients with current BC, 17.9% (14/78) patients with prior BC, and 0.0% (0/55) without BC. Bone metastases were associated with invasive and advanced stage BC and, on MRI, with location in sternum, ribs, or clavicles, larger size, multiplicity, and T1 hypointensity (all P &lt; 0.01 in tests of overall association).

Conclusion
Of clinically confirmed breast MRI–detected bone lesions, 30% were bone metastases; all were detected in patients with current or prior BC. Metastases were associated with advanced stage, invasive carcinoma, larger lesion size, multiplicity, low T1 signal, and non-spine location.
Evaluation of membrane quality and entrance pressure of oil-based mud at elevated temperatures
Authors: Hashem Shahad , AL-Bazali Talal , Garrouch Ali , Owayed Jalal 
Published: August 2022

AbstractThis study fully explored the impact of temperature on the membrane quality of oil-based mud (OBM) using static gravimetric measurements, membrane efficiency and entrance pressure tests. More than 30 shale samples were used to assess the membrane behavior of several OBMs under elevated temperatures. Results suggested that OBM acted as a semi-permeable membrane at low temperatures (25–55˚C) since ion flow out of OBM and into shale was restricted despite the existence of a large ionic concentration gradient, while water flowed freely out of shale and into OBM because of the existence of a chemical potential difference. For temperatures higher than 55˚C, relatively higher ion flux into shale and slightly lower water flow out of shale was observed. Excessive heat may have possibly destabilized or even destroyed the emulsifier's structure that serves as a mechanism through which OBM performs as a semi-permeable membrane. The instability of OBM's emulsifier was further confirmed through entrance pressure testing where an appreciable reduction in entrance pressure of OBM was measured at high temperatures.
A Consistent and Robust Test for Autocorrelated Jump Occurrences
Authors: Kwok Simon 
Published: August 2022

AbstractWe develop a nonparametric test for the temporal dependence of jump occurrences in the population. The test is consistent against all pairwise serial dependence, and is robust to the jump activity level and the choice of sampling scheme. We establish asymptotic normality and local power property for a rich set of local alternatives, including both self-exciting and/or self-inhibitory jumps. Simulation study confirms the robustness of the test and reveals its competitive size and power performance over existing tests. In an empirical study on high-frequency stock returns, our procedure uncovers a wide array of autocorrelation profiles of jump occurrences for different stocks in different time periods.
The Imperturbable Seriousness of the Circus Buffoon: The Shakespearean Clown on the Threshold of Modern Comedy
Authors: Andersson Peter K 
Published: August 2022

Abstract
Around the middle of the nineteenth century, there arose a type of circus performer in England called ‘Shakespearean clowns’. These clowns constituted a transitory figure between the age of Georgian pantomime clowns and the establishment of the typical circus clown in the later part of the century. One of the more neglected representatives of the genre was James Clement Boswell, who enjoyed a brief period of success in England before becoming a sensation in Paris during the 1850s. Although he was universally praised, his clowning also evoked bafflement. This article studies reviews of and periodical articles on Boswell in order to get a picture of his performances and clown persona, and of how critics perceived him and turned him into an example of the melancholy clown trope. The resistance that Boswell’s act and persona offered to the writers, however, illustrates that he was part of a change in the figure of the clown from its early nineteenth century incarnation to the twentieth-century clown and comic. Boswell’s clowning prefigures the irony and deadpan comedy that would become more prevalent in modern comedy. He is also illustrative of the increasing detachment of the clown figure from representations of a social reality, and the creation of the modern circus clown as an essentially unreal character that epitomizes a separate outlook on life.