bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH PEMBERIAN KOMPRES JAHE TERHADAP PENURUNAN INTENSITAS NYERI ARTHRITIS GOUT PADA LANSIA
Authors: Emil Emil  
Published: October 2022

ABSTRAK
Arthritis gout merupakan suatu penyakit peradangan pada persendian yang dapat diakibatkan oleh kelebihan asam urat yang diproduksi dalam tubuh sehingga menumpuk dan dapat membentuk kristal pada persendian. Adapun cara menurunkan nyeri pada sendi salah satunya yaitu terapi non farmakologi dengan kompres jahe. Pemberian kompres jahe dapat menurunkan nyeri sendi karena jahe dapat meningkatkan kemampuan kontrol terhadap nyeri, jahe memiliki rasa pedas karena jahe mengandung senyawa seperti minyak atsiri zingiberena (zingirona), bisabolena, zingiberol, kurkumen, filandrena, gingerol, dan rasa hangat yang ditimbulkannya membuat pembuluh darah terbuka dan memperlancar sirkulasi darah, suplai makanan dan oksigen menjadi lebih baik sehingga nyeri sendi akan berkurang. Penelitian ini bertujuan untuk mengetahui adanya pengaruh pemberian kompres jahe terhadap penurunan intensitas nyeri arthritis gout pada lansia di Posbindu Sehati RW 04 Bojong Indah Kelurahan Rawa Buaya. Penelitian ini menggunakan jenis penelitian pra eksperimen dengan desain yang digunakan dalam penelitian ini adalah one-grup pre-post test design. Teknik pengambilan sampel menggunakan total sampling. Sampel dalam penelitian ini berjumlah 22 responden. Hasil uji paired samples t-test menunjukkan p-value 0,000 (<0,05). Dapat disimpulkan bahwa adanya pengaruh pemberian kompres jahe terhadap penurunan intensitas nyeri arthritis gout pada lansia di Posbindu Sehati RW 04 Bojong Indah Kelurahan Rawa Buaya.
Kata Kunci : Arthritis Gout, Intensitas Nyeri, Kompres Jahe, Lansia

ABSTRACT
Arthritis gout is an inflammatory disease of the joints that can be caused by excess uric acid produced in the body so that it accumulates and can form crystals in the joints. As for how to reduce pain in the joints, one of them is non-pharmacological therapy with ginger compresses. Giving ginger compresses can reduce joint pain because ginger can increase the ability to control pain, ginger has a spicy taste because ginger contains compounds such as zingiberene (zingirona) essential oil, bisabolena, zingiberol, curcumin, filandrena, gingerol, and the resulting warm feeling makes blood vessels open and facilitate blood circulation, supply of food and oxygen for the better so that joint pain will be reduced. This study aims to determine the effect of giving ginger compresses on reducing the intensity of gouty arthritis pain in the elderly in Posbindu Sehati RW 04 Bojong Indah, Rawa Buaya Village. This study uses a pre-experimental type of research with the design used in this study is a one-group pre-post test design. The sampling technique used was total sampling. The sample in this study amounted to 22 respondents. The results of the paired samples t-test showed a p-value of 0.000 (<0.05). It can be concluded that there is an effect of giving ginger compresses to reduce the intensity of gouty arthritis pain in the elderly at Posbindu Sehati RW 04 Bojong Indah, Rawa Buaya Village.
Keywords: Gout Arthritis, Pain Intensity, Ginger Compress, Elderly
Quote "Echo" of J. Keats in the Late Lyrics of Anna Akhmatova
Authors: Belousova Ol'ga Geral'dovna 
Published: October 2022

The subject of the study is explicit and hidden references to the work of John Keats in the works of Anna Akhmatova "Poem without a hero" and the cycle of poems "From a burnt notebook". The object of the study is the principle of "mirror writing" implemented through references to Keats, which allows using embedded references to various works of world culture located one inside the other. The author examines in detail such aspects of the topic as the use of quotations in the text and in the frame of the text, the roll call of citations among themselves and with other works. Special attention is paid to the motive of meeting with a dead lover formed with the help of allusions, which is present both in Keats' poems and in the "Poem without a Hero", and due to the principle of "mirror writing" is formed in the implicature of the cycle "From a burnt notebook". The main conclusions of the study are the detailed references to the form and content of John Keats' poems in the works of Anna Akhmatova. A special contribution of the author to the study of the topic is the connection established for the first time between the image of "embalming" mentioned in the Poem without a Hero and in Keats' poem "A Pot of Basil", the epigraph from which is used in the cycle "From a burnt notebook". The novelty of the research lies in clarifying the principle of "mirror writing", the quote "echo", implying the reflection of one quote in another and building a kind of chain of references in the work: Keats refers to Boccaccio, Boccaccio to Virgil, etc.
Cinnamaldehyde regulates mitochondrial quality against hydrogen peroxide induced apoptosis in mouse lung mesenchymal stem cells via the PINK1/Parkin signaling pathway
Authors: Ke Shiwen , Zhu Wei , Lan Zhihui , Zhang Yuanbing , Mo Lisha , Zhu Guoshuang , Liu Liangji 
Published: October 2022

Background
Idiopathic pulmonary fibrosis (IPF) is a fatal respiratory disease without effective treatments. Mitochondrial dysfunction weakens the ability of mesenchymal stem cells (MSCs) to repair the distal lung epithelium, which is a probable pathogenesis of IPF. In previous research, we found that cinnamaldehyde (CA) can maintain the mitochondrial morphology of MSCs.

Methods
This present study evaluated the effect and mechanism of CA on murine lung MSCs using the hydrogen peroxide model. Antioxidant effects and mitochondrial function were determined using flow cytometry. The mRNA levels of mitochondrial dynamics and the expressions of autophagy-related proteins were also detected.

Results
CA can increase the levels of SOD, MMP and ATP, decrease the rate of ROS and apoptosis, and restore the mitochondrial structure. CA can also improve the mRNA expression of MFN1, MFN2, FIS1, DRP1, OPA1, and PGC-1α, increase the expression of LC3 II and p62 and promote the PINK1/Parkin signaling pathway. Our results demonstrated that CA can control mitochondrial quality and avoid apoptosis, which may be associated with the regulation of the PINK1/Parkin signaling pathway.
Use of fermented spent coffee grounds as a substrate supplement for rearing black soldier fly larvae, Hermetia illucens (L), (Diptera: Stratiomyidae)
Authors: Khaekratoke Kanyanat , Laksanawimol Parichart , Thancharoen Anchana 
Published: October 2022

Background
Spent coffee grounds (SCG), an increasingly abundant waste product with environmental disposal problems, has been used as a dietary supplement for many animals and have the potential to be used as a dietary supplement for black soldier fly (BSF) larvae; however, its effective use is still under scrutiny. To date, no studies have considered the use of SCG after microbial fermentation (fSCG) and its effects on BSF life history.

Methods
A mixture of fruit and vegetable pulp residue supplemented with one of six different fSCG percentages (0%, 20%, 40%, 60%, 80%, and 100% by weight) were provided as a diet substrate in order to evaluate the effect of the fSCG quantity on BSF growth, yield, and conversion ability.

Results
The addition of fSCG to the pulp diet prolonged larval development times, while 100% fSCG affected the larval survival rate and resulted in a male-biased adult sex ratio. The 20–40% fSCG and 40–60% fSCG treatments supported the largest prepupal and mature larval sizes, respectively. The highest waste reduction efficiency and feed conversion rate by BSF larvae was found with 20% fSCG, similar to the control (0% fSCG).

Discussion
From the short rearing time, high yield, and high bioconversion efficiency, a 20% fSCG supplementation of the mixed pulp was recommended for rearing BSF larvae. These data are valuable for coffee by-product waste management in urban areas.
Trophic Status of Shanti Sagara Reservoir:	Implications on Nutrient Management in Reservoir Catchment
Authors: Desai V. Rohan , Bhagwat Tejaswini Nikhil 
Published: October 2022

Water quality assessment of Shanti Sagara reservoir for drinking water supply and for water allocation to meet the demands in the semiarid climate is aimed. Seasonal water sampling (Pre monsoon, December 2021 & Post monsoon, May 2022) at 2 depths to investigate physico-chemical parameters and assess the Water Quality index based on IS 10500: 2012 is found to be poor in pre monsoon, December 2021 and very poor in post monsoon, May 2022. Trophic status of the reservoir assessed based on Carlson’s Trophic State Classification (Secchi Depth, Total Nitrogen and Total Phosphorous) indicated that the reservoir is Hypereutrophic for Post Monsoon. This calls for assessment of internal nutrient load (silt characteristics) and external loading from the reservoir catchment (fertilizer from agriculture land) and the domestic water and the sewage water has contributed to high concentration of phosphorous (P) in Rudrapura and Jakli near Somalapura.
Soil texture (sandy clay, silty loam, silty clay and sandy clay loam) in the reservoir catchment compliments high concentration of suspended sediment that increasers the turbidity in the reservoir. Turbidity present in the water alters the taste, colour and odour of the water and oxygen from the surface cannot be mixed to the bottom layer and oxygen is not released by photosynthesis in absence of light penetration (high turbidity levels) resulting in anoxic condition. Total Nitrogen (TN) in the catchment soil that contributes to the bottom of the reservoir is found to be high (201-217 kg/acre). Agriculture runoff in the month of (May, 2022) owing to precipitation results in high sediment concentration, that contributes to high nitrogen levels in the reservoir.
Nutrients in suspended Sediments that have entered the reservoir altered the nutrient cycle in the reservoir ecosystem. High nutrient concentration in the silt characteristics i,e total nitrogen (159-168 kg/acre) and phosphorous (10.1-13.4 kg/acre) is due to stratification caused do level to low in hypolimnion layer and anoxic condition during summer resulting in growth of Phytoplankton the eutrophication. The suggested nutrient management strategies for the reservoirs catchment are optimizing nutrient application to the crop land, microbial water treatment before supplying it for drinking purpose, soil conservation structures in the reservoir catchment to restrict sediment entry to the reservoir and sewage treatment plant for the rural settlement.
Investigation and Identification of Various Garden Spider Species in Two Distinct Locations
Authors: Shah Nitu , Kumari Bibha 
Published: October 2022

Aim: Spiders require all environments in which they can survive, and they are regarded as a helpful indicator of the overall species richness and health of terrestrial communities. They are particularly sensitive to natural world disturbances. As a result, the current study was carried out to investigate and identify the diverse garden spider species at two distinct locations: a large college campus garden and a house garden (small).
Place and Duration of Study: Garden of Magadh Mahila College (Patna, India) and the house garden (Patna city, India), between July 2001 to March 2022.
Methodology: Visual examination and camera capture of photographs of spiders in both research sites, and identification based on general shape, size, distinctive colour pattern, number and positioning of eyes, length and arrangement of their legs, and so on.
Results: Spiders are among the most diverse groups of organisms that exist in almost all microhabitats, as evidenced by the presence of 07 families, 15 genus, and 25 species in a small area. Due to their small numbers, this group cannot be disproved in conservation studies. Less species were found in the small garden in the house that was located in a well-built area, whereas a large number of different species of spiders were found in the college campus garden with a larger area of vegetation.
Conclusion: According to this brief investigation, multiple species were present, each belonging to a different taxonomic group. As a result of this research, we will be able to gain a better understanding of spider diversity and taxonomy.
Status, Challenges and Mitigation Strategies of Production of Non Timber Forest Products in Mundemba Municipality, Southwest Region Cameroon
Authors: Ndah Njoh Roland , Taku Julie , Lucha Celestine Fonyikeh-Bomboh , Mutange Helga Ekole 
Published: October 2022

Land clearing for plantation and settlement establishment has been a prominent driving force for forest ecosystem destruction. This study aimed at evaluating the status, challenges and mitigation strategies of the selected NTFPs produced and Mark¹eted in the study site. This study was carried out in the municipality of Mundemba South West Region Cameroon. Data were collected with the used of open and close ended questionnaires, key informants interviews and field observations. The questionnaires were divided into IV sections. Section I socio-demographic characteristics, section II on the status of the different NTFPs produced and marketed section III on the challenges and section IV on mitigation strategies. Data were subjected to descriptive analyses and were treated using statistical software program IBM SPSS statistics. Chi square Pearson test was used to determine the association. Results showed that 59.00 percent were men while 41.00 percent were women. Based on the IUCN red list categories, 6 of the NTFPs were noticed as least concerned, 4 of the NTFP species are near threatened, while none of the species were noticed to be extinct. The main challenge for production was limited land with 51.00 percent while the least challenge of limited knowledge for production was noticed to 2% and was not significantly different(x2cal = 0.593, x2 table value=0.917). The main challenge for marketing was reported as insecurity with 39 % while the least was failure of buyers to keep to time with 8.00 percent and was significantly different (X2cal= 1.052,x2 table value =0.958). The government strategies for mitigating challenges of production and marketing (x2cal =2.988, x2cal =0.224) was significantly different. The major mitigation of road construction had a percentage of 83.00 percent, while the least noticed for mitigations production and marketing was provision of farm inputs with a percentage of 6 %. Therefore, proper management will definitely lead to improve production and marketing of NTFPs.
Evaluation of Microbiological and Physico-Chemical Parameters of Juices Sold in the Streets of the City of Man (Côte D’Ivoire): Case of Zingiber officinale and Hibiscus sabdariffa
Authors: Carole Koffi Affoué , Clément Kouassi Kouassi , Daouda Nimaga , Rose Koffi-Nevry 
Published: October 2022

Objective: To study the microbiological and physico-chemical quality of traditional drinks based on Hibiscus sabdariffa and Zingiber officinale sold in the streets of Man (Côte d’Ivoire).
Materials and Methods: The material consisted of Hibiscus sabdariffa and Zingiber officinale juices. A survey was conducted among the population and vendors. Several microbiological standards were used for the determination of mesophilic aerobic germs, Escherichia coli, Staphylococcus sp. and Salmonella sp. Physicochemical parameters such as: reducing sugar (g/100 mL), pH, Brix degree (°Brix), temperature (°Celcius), conductivity (ɥs/cm), calcium, phosphorus, zinc and iron (all three in mg/g) were determined in the juice.
Results: At the survey level, several sales locations were used by the vendors as a strategic environment to attract customers. 40% in small alleys, 19% at the market, 18% at the bus station, 14% near schools and (9%) near administrations. Regarding the microbiological results, there is a strong contamination of the mesophilic aerobic germs with a value of 1.82×105 and Total Coliforms (TC) with a value of 8.06×105 of the juices made from Hibiscus sabdariffa making the juices unfit for consumption.
Physicochemical analyses of Hibiscus sabdariffa and Zingiber officinale juices yielded the following highest values: pH (2.3 ± 0.05) (4.24 ± 0.31), temperature (15.65 ± 3.35) (17.7 ± 1 C°), conductivity (369 ± 88 ɥs/cm) (186.55 ± 12.05), calcium (0.88 and 0, 44 mg/g), phosphorus (2.4 and 1.26 mg/g), iron (0.37 and 0.53 mg/g), °Brix (20.5 ± 4.5)(20 ± 2) and reducing sugars (8.38 ±1.4) (17.7 ±0.68 g/100 mL).
Conclusion: The present study allowed to assess the microbiological and physicochemical quality of the drinks based on Hibiscus sabdariffa and Zingiber officinale. The microbiological results obtained, are worrying for the consumers. Also, the whole of the parameters determined in the various juices allow to have an idea of the risk incurred by the consumers.
Qualitative Analysis of Patient–Physician Discussions Regarding Anticoagulation for Atrial Fibrillation
Authors: Martinez Kathryn A. , Hurwitz Heather McKee , Rothberg Michael B. 
Published: October 2022

ImportanceFor patients with atrial fibrillation (AF), the decision to initiate anticoagulation involves the choice between warfarin or a direct oral anticoagulant (DOAC). How physicians engage patients in this decision is unknown.ObjectiveTo describe the content of discussions between patients with AF and physicians regarding choice of anticoagulation.Design, Setting, and ParticipantsThis qualitative content analysis included clinical encounters between physicians and anticoagulation-naive patients discussing anticoagulation initiation between 2014 and 2020.Main Outcomes and MeasuresThemes identified through content analysis.ResultsOf 37 encounters, almost all (34 [92%]) resulted in a prescription for a DOAC. Most (25 [68%]) patients were White; 15 (41%) were female and 22 (59%) were male; and 24 (65%) were aged 65 to 84 years. Twenty-one physicians conducted the included encounters, the majority of whom were cardiologists (14 [67%]) and male (19 [90%]). The analysis revealed 4 major categories and associated subcategories of themes associated with physician discussion of anticoagulation with anticoagulation-naive patients: (1) benefit vs risk of taking anticoagulation—in many cases, this involved an imbalance in completeness of discussion of stroke vs bleeding risk, and physicians often used emotional language; (2) tradeoffs between warfarin and DOACs—physicians typically discussed pros and cons, used persuasive language, and provided mixed signals, telling patients that warfarin and DOACs were basically equivalent, while simultaneously saying warfarin is rat poison; (3) medication costs—physicians often attempted to address patients’ questions about out-of-pocket costs but were unable to provide concrete answers, and they often provided free samples or coupons; and (4) DOACs in television commercials—physicians used direct-to-consumer pharmaceutical advertising about DOACs to orient patients to the issue of anticoagulation as well as the advantages of DOACs over warfarin. Patients and physicians also discussed class action lawsuits for DOACs that patients had seen on television.Conclusions and RelevanceThis qualitative analysis of anticoagulation discussions between physicians and patients during clinical encounters found that physicians engaged in persuasive communication to convince patients to accept anticoagulation with a DOAC, yet they were unable to address questions regarding medication costs. For patients who are ultimately unable to afford DOACs, this may lead to unnecessary financial burden or abandoning prescriptions at the pharmacy, placing them at continued risk of stroke.
Social Determinants Associated With Exposure to Childhood Parental Bereavement and Subsequent Risk for Psychiatric Disorders
Authors: Denckla Christy A. , Averkamp Natalie M. , Slopen Natalie , Espinosa Dice Ana Lucia , Williams David , Shear M. Katherine , Koenen Karestan C. 
Published: October 2022

ImportancePrevalence of childhood parental death varies by race and ethnicity and socioeconomic status, yet whether similar variation persists in the association with lifetime psychiatric disorder is unknown.ObjectiveTo assess whether race and ethnicity and parental educational attainment are associated with the risk of death of a parent; to determine whether the risk for lifetime psychiatric disorder associated with death of a parent was moderated by race and ethnicity and highest parental educational attainment; and to examine a potential intersection of race and ethnicity with parental educational attainment in the risk of lifetime psychiatric disorder associated with death of a parent.Design, Setting, and ParticipantsThis retrospective cohort study used data from the National Comorbidity Study: Adolescent Supplement (NCS-A), 2001 to 2004. Participants included youth aged 13 to 18 years, restricted to Black, Hispanic, and White youth due to power limitations. Data were analyzed from February 26, 2021, to April 21, 2022.ExposureDeath of a parent during childhood.Main Outcomes and MeasuresThe primary study outcome was any lifetime Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) psychiatric disorder, assess via assessed via structured clinical interviews.ResultsAmong 9501 youth (mean [SD] age, 15.2 [1.5] years; 50.9% female), including 511 youth who had experienced parental death and 8990 youth who had not, the cumulative hazard of parental death by age 18 years was approximately doubled for Hispanic (10.1%; 95% CI, 6.9%-14.7%) and Black (14.0%; 95% CI, 10.6%-18.4%) youth compared with White youth (6.0%; 95% CI, 4.7%-7.8%). Similar patterns were noted by parental educational attainment: the cumulative hazard of parental death for youth of parents with less educational attainment was nearly double (10.1%; 95% CI, 8.1%-12.6%) compared with youth of parents with more education (6.6%; 95% CI, 5.2%-8.4%). Death of a parent was positively and significantly associated with risk of any lifetime psychiatric disorder (aOR, 1.34; 95% CI, 1.03-1.75) compared with youth who had not experienced death of a parent. However, this association was not moderated by race and ethnicity (aOR, 1.05; 95% CI, 0.58-1.92) or parental educational attainment (aOR, 1.19; 95%, 0.70-2.04), although power analyses suggest that larger sample sizes are needed.Conclusions and RelevanceIn this cross-sectional study, Black and Hispanic youth experienced elevated parental death compared with White youth, yet the risk for any lifetime psychiatric disorder after parental death was not significantly moderated by race and ethnicity or parental education. Both individual- and population-level interventions may be needed to address the increased risk of psychiatric disorders, although additional studies with larger sample sizes are needed.
Capturing the sequence of events during the water oxidation reaction in photosynthesis using XFELs
Authors: Simon Philipp S. , Makita Hiroki , Bogacz Isabel , Fuller Franklin , Bhowmick Asmit , Hussein Rana , Ibrahim Mohamed , Zhang Miao , Chatterjee Ruchira , Cheah Mun Hon , Chernev Petko , Doyle Margaret D. , Brewster Aaron S. , Alonso‐Mori Roberto , Sauter Nicholas K. , Bergmann Uwe , Dobbek Holger , Zouni Athina , Messinger Johannes , Kern Jan , Yachandra Vittal K. , Yano Junko 
Published: October 2022

Ever since the discovery that Mn was required for oxygen evolution in plants by Pirson in 1937 and the period‐four oscillation in flash‐induced oxygen evolution by Joliot and Kok in the 1970s, understanding of this process has advanced enormously using state‐of‐the‐art methods. The most recent in this series of innovative techniques was the introduction of X‐ray free‐electron lasers (XFELs) a decade ago, which led to another quantum leap in the understanding in this field, by enabling operando X‐ray structural and X‐ray spectroscopy studies at room temperature. This review summarizes the current understanding of the structure of Photosystem II (PS II) and its catalytic centre, the Mn4CaO5 complex, in the intermediate Si (i = 0–4)‐states of the Kok cycle, obtained using XFELs.