bluuebunny/crossref_metadata_2025_split huggingface dataset:
Conus medullary arteriovenous malformation mimicking intramedullary tumor: a case report
Authors: Monica Maria , Mahadewa Tjokorda Gde Bagus , Awyono Steven , Prakoso Dicky Teguh 
Published: November 2022

Abstract
Background
Vascular malformation of the spine accounted for 3–4% of all intradural lesions. Spinal arteriovenous malformation (AVM) is often missed because of overlapping symptoms with other pathology and ambiguous imaging. Here, we report a conus medullary AVM that mimics intramedullary tumours either from clinical findings or MR imaging.

Case presentation
We report a 24-year-old man with left foot monoparesis, paresthesia, and intermittent claudication for the last 3 months. Magnetic resonance imaging revealed a strongly enhanced intramedullary lesion with a hypointense signal on T1-weighted images and a hyperintense signal on T2-weighted images without flow void, suggesting an intramedullary tumour of ependymoma. Left-sided hemilaminectomy was performed, revealing an AVM on conus medullary. Microsurgical resection was performed by subsequently ligating the arterial feeder and draining vein using a temporary clip. Improvement of neurological status without postoperative sequelae was noted.

Conclusions
Because of the similarity in epidemiology, symptoms, clinical progression, and imaging, suspicion of spinal AVM should remain. This case highlights that appropriate and meticulous surgical resection can preserve the patient's neurological function.
Impact of highly active antiretroviral drug therapy (HAART) on biochemical, hematologic, atherogenic and anthropometric profiles of human immunodeficiency virus patients at a tertiary hospital in Owo, Nigeria
Authors: Ademuyiwa Success E. A. , Saliu Ibrahim Olabayode , Akinola Busuyi Kolade , Akinmoladun Afolabi Clement , Olaleye Mary Tolulope , Ademuyiwa Adewole I. , Akindahunsi Afolabi Akintunde 
Published: November 2022

AbstractBackgroundHighly active antiretroviral drug therapy (HAART) remains the only officially available option for the management of human immunodeficiency virus (HIV) infection at designated medical institutions in Nigeria. This study investigated the impact of HAART on glucose level, lipid profile, blood parameters and growth indices of HIV-infected patients at a tertiary health center in Nigeria. Biochemical and hematologic indices were determined in HIV patients on HAART at the Federal Medical Centre (FMC), Owo, Nigeria. Plasma glucose and lipid profile were biochemically determined in 140 age-matched individuals divided into three groups: Group I (n = 70) comprised seventy clinically diagnosed and laboratory-confirmed HIV-positive patients before receiving HAART (HIV-positive group); Group II (n = 70) comprised the same set of HIV-positive patients who had received HAART for 1 year (HAART group); and Group III (n = 70) comprised healthy controlled subjects who proved HIV-negative (HIV-negative group). Growth indices were used to monitor the changes in immune response (white blood cell counts) of the HIV-infected patients.ResultsHAART ameliorated reduced body mass index and disorder in white blood cell counts but not dyslipidemia and hyperglycemia caused by HIV infection. Results confirmed the effectiveness of HAART in preventing the development of full-blown acquired immune deficiency syndrome in HIV-positive patients. However, increases in cholesterol and low-density lipoprotein-cholesterol levels coupled with increased atherogenic index occasioned by HAART portend the risk of cardiovascular disease.ConclusionsHIV infection has a negative impact on the anthropometric, hematologic and biochemical indices of patients. Although HAART is helpful to improve anthropometric and hematological indicators, there is a need to improve drug regimens to reduce or eliminate undesirable metabolic complications.
Functional structure analysis and genome-wide identification of CNX gene family in cotton
Authors: Xu Nan , Zhang Hong , Zhang Yuexin , Fan Yapeng , Wang Jing , Malik Waqar Afzal , Rui Cun , Han Mingge , Lu Xuke , Chen Xiugui , Wang Junjuan , Wang Delong , Wang Shuai , Chen Chao , Guo Lixue , Zhao Lanjie , Ye Wuwei 
Published: November 2022

Abstract
Background
Under abiotic stress conditions, cotton growth is inhibited and yield losses are severe. Identification of calnexin family members and function analysis under abiotic stress laid the foundation for the screening of stress-related candidate genes.

Results
A total of 60 CNX family members have been identified in Gossypium hirsutum, G. barbadense, G. arboreum, and G. raimondii, and they were divided into two categories: CNX and CRT genes. Through the construction of a phylogenetic tree, they were subdivided into three classes. Further analysis of chromosome localization, conserved promoters, gene structure and selection under pressure showed that the family members were highly conserved in the evolution process. Analysis of cis-acting elements in the promoter regions showed that CNX family genes contain regulatory elements for growth and development, anaerobic, drought, defense and stress response, and plant hormones. Using RNA-seq data to study the expression pattern of GhCNX genes under cold, hot, salt stress and Polyethylene glycol, it was observed that the gene expression levels changed by different degrees under different stress conditions, indicating that GhCNX members were involved in the regulation of multiple biological stresses.

Conclusion
This study provides an insight into the members of cotton CNX genes. The results of this study suggested that CNX family members play a role in defense against adversity and provide a foundation for the discovery of stress-related genes.
Assessing the level of knowledge, uptake of hepatitis B virus vaccine, and its determinants among health workers across various levels of health facilities in Ondo, South West, Nigeria
Authors: Oni Oluwatosin Idowu , Osho Olanrewaju Patrick , Oluwole Mathew Temitope , Osho Evelyn Salewa , Ogungbeje Aanuoluwapo , Raji Habeebat Motunrayo 
Published: November 2022

Abstract
Problem considered
Research has shown that health care personnel is at higher risk of acquiring the disease than the general population. In spite of this challenge, there has been a low vaccination record among the Health Workers
The aim of this study was to investigate the relationship between knowledge, attitude, perception, and practice of hepatitis B vaccination among health workers in Akure South Local Government Area of Ondo State, Nigeria

Methods
An institution-based cross-sectional study was conducted with 260 health professionals working at primary health centers (40), private hospitals (60), and tertiary health institutions (160). Data was collected by using self-administered questionnaires distributed at the participant’s work unit and analyzed using SPSS version 20.

Results
The result showed that there was a statistically significant relationship between the knowledge of Health workers about the HBV vaccine and vaccine uptake.
While all the non-vaccinated health workers showed interest in taking the vaccine, the majority of them (80.4 %) suggested that the vaccine should be given free to health workers.

Conclusion
The study revealed that the health workers had a good knowledge of hepatitis infection but not the vaccination which affected vaccine uptake as a significant relationship exists between the two. Also, the greatest hindrance to the uptake of the vaccine is the cost of the vaccine. HBV vaccination should be made compulsory as part of occupational protection measures and made readily available gratis for all health workers.
Altered Intrinsic Brain Activity Related to Neurologic and Motor Dysfunction in Diabetic Peripheral Neuropathy Patients
Authors: Xin Haotian , Fu Yajie , Feng Mengmeng , Wang Shengpei , Sui Chaofan , Gao Yian , Zhang Nan , Guo Lingfei , Wen Hongwei , Liang Changhu 
Published: November 2022

AbstractContextBrain functional alterations in type 2 diabetes with diabetic peripheral neuropathy (DPN) related to motor dysfunction remain largely unknown.ObjectiveWe aimed to explore intrinsic resting brain activity in DPN.MethodsA total of 28 patients with DPN, 43 patients with diabetes and without DPN (NDPN), and 32 healthy controls (HCs) were recruited and underwent resting-state functional magnetic resonance imaging. We calculated the amplitude of low-frequency fluctuation (ALFF), fractional ALFF (fALFF), and regional homogeneity (ReHo). One-way analysis of covariance was applied to evaluate the above indicators among the 3 groups, and the mean ALFF/fALFF/ReHo values of altered brain regions were then correlated with clinical features of patients.ResultsCompared with the NDPN group, the DPN group showed significantly decreased ALFF values in the right orbital superior frontal gyrus (ORBsup) and medial superior frontal gyrus (SFGmed), and increased ALFF values in the left inferior temporal gyrus (ITG) and decreased fALFF values in the right SFGmed. Compared with HCs, the NDPN group showed increased ALFF values in the right ORBsup, middle frontal gyrus, and left orbital middle frontal gyrus, and decreased fALFF values in the right middle temporal gyrus. Notably, the mean ALFF values of the right ORBsup were significantly negatively correlated with Toronto Clinical Scoring System scores and gait speed in diabetics. The mean ALFF/fALFF values of right SFGmed and the mean ALFF values of left ITG and right ORBsup were significantly differentiated between DPN and patients witht NDPN in receiver operating characteristic curve analysis.ConclusionPatients with DPN have abnormal brain activity in sensorimotor and cognitive brain areas, which may implicate the underlying neurophysiological mechanisms in intrinsic brain activity.
Stevens-Johnson Syndrome – clinical symptoms, etiology, pathophysiology and medical treatment - a review of the literature
Authors: Szymkiewicz Karolina , Marczak Aleksandra , Hordejuk Michalina , Hyjek Michał 
Published: November 2022

Stevens-Johnson syndrome (SJS) is a rare disease of the skin and mucous membrane. It develops as a result of a sudden skin reaction, which is most often triggered by the use of certain drugs. It is characterized by acute epidermal necrosis.
The syndrome can lead to many complications and death. Currently, there are no guidelines and management schematics for this disease. Treatment has changed over the years due to the discovery of the possible pathomechanism of SJS. Nevertheless, because of the rarity of the disease, there is a lack of adequate prospective randomized studies that could provide valuable information on treatment.

Objective:
The purpose of this study was to present Stevens-Johnson syndrome, including clinical features, etiology, pathomechanism, complications and treatment.

Methods:
A literature search was performed in the PubMed medical publication database using the following keywords: Stevens-Johnson syndrome, acute drug-induced skin reaction, cutaneous adverse drug reactions.

Results:
Stevens-Johnson syndrome is an example of an acute cutaneous reaction to certain medicinal substances. The pathomechanism is not fully understood. There is an association of genetics with the risk of developing symptoms of the syndrome in selected populations. Treatment formerly was based on glucocorticosteroids, but now IVIG (intravenous immune globulin) is used. Dehydration, pneumonia or sepsis may develop as a complication of the syndrome.

Conclusions:
The discovery of a genetic predisposition to develop Stevens-Johnson syndrome offers the possibility of future effective disease prevention.
It is necessary to create medical procedure schemes for the diagnosis and treatment of this disorder. The discovery of the possible pathomechanism has allowed the use of IVIG in the treatment of the syndrome. Effective and prompt diagnosis and treatment can prevent life-threatening complications and death from SJS.
Existence of ground state solutions for critical quasilinear Schrödinger equations with steep potential well
Authors: Xue Yan-Fang , Zhong Xiao-Jing , Tang Chun-Lei 
Published: November 2022

Abstract
We study the existence of solutions for the quasilinear Schrödinger equation with the critical exponent and steep potential well. By using a change of variables, the quasilinear equations are reduced to a semilinear one, whose associated functionals satisfy the geometric conditions of the Mountain Pass Theorem for suitable assumptions. The existence of a ground state solution is obtained, and its concentration behavior is also considered.
Achieving excellent oxidation resistance and mechanical properties of TiB2–B4C/carbon aerogel composites by quick-gelation and mechanical mixing
Authors: Li Pengfei , Shi Minxian , Deng Zongyi , Han Pengkun , Yang Tingli , Hu Rui , Dong Chuang , Wang Rui , Ding Jie 
Published: November 2022

Abstract
Thermal protection system (TPS) is of great significance to launch hypersonic flight and landing process of hypersonic vehicles, which can effectively shield the hypersonic vehicle from severe aerodynamic heating encountered. Phenolic aerogels play an important role in TPS due to their characteristics of low density, high porosity, and low thermal conductivity. However, phenolic aerogel is easy to be oxidized at elevated temperatures under oxidizing environments, which severely limits its large-scale application as thermal insulation materials in TPS. In this study, a novel TiB2–B4C/carbon (TB/C) aerogel composite was synthesized by introducing TiB2 and B4C particles into phenolic aerogels through quick-gelation and mechanical mixing. The developed aerogel composites were characterized by scanning electron microscopy, Fourier transform infrared, thermal analysis, etc., to evaluate their microstructure, oxidation resistance, and mechanical properties. Experimental evidence showed that TiB2 and B4C particles reacted with the oxygen-containing molecules to form TiO2–B2O3 layer, which effectively improved oxidation resistance and mechanical properties of phenolic aerogel composites.
MacArthur’s need for speed: Why Fuller was fired at Biak
Authors: Hall Mary T. 
Published: November 2022

AbstractThe US campaign for Biak in 1944 was one of the most challenging, albeit little known, operations of the Pacific war. Major General Horace Fuller’s HURRICANE Task Force faced a tenacious enemy determined to hold the island’s three airfields at all costs. Grossly underestimating the number of Japanese defenders on Biak, MacArthur and Kreuger allocated Fuller only two regimental combat teams for the initial invasion in May 1944. Once ashore, the US troops encountered a shift in Japanese tactics from defending at the water’s edge to using inland fukkaku, honeycombed underground defensive positions that masked Japanese troops and artillery. When the task force failed to deliver the airfields as quickly as desired by General Douglas MacArthur, Lieutenant General Walter Krueger relieved Fuller as task force commander and replaced him with Lieutenant General Robert Eichelberger. This article contends that Krueger did not have good cause to relieve Fuller; rather, he simply did so to placate MacArthur, who, for a multitude of reasons, pressured Krueger for a fast victory. I assess flaws in the planning and execution of the operation, MacArthur’s motives, and personality dynamics between MacArthur and Krueger to support my conclusion that Fuller was ultimately a victim of MacArthur’s impatience.
Multilingualism in the Banat: A Focus on Intellectual Perspectives through the Analysis of Literary Works
Authors: Laihonen Petteri 
Published: November 2022

SummaryThe Banat has been one of Europe’s most multilingual regions since the 18thcentury. From the 19thcentury European intellectuals have been engaged in building nations, which has resulted in the marginalization of multilingualism in many forms. The monolingual literary novel has been described as one of the important instruments in this process. Phenomena remaining resistant to this idea are brought into focus through the analysis of multilingualism in four novels written by authors from the Banat. In this manner, the chances of multilingualism in the context of national cultures and intellectuals are examined. As a conclusion, it is argued that the multiplicity of languages in literature presents an opportunity for a better cross-cultural understanding.
Imagining Borderlands and Remembering Multilingualism: The Adriatic Trilogy of Nedjeljko Fabrio
Authors: Czerwiński Maciej 
Published: November 2022

Summary
The article analyses multilingual and multicultural diversity in the narrative prose of the Croatian writer Nedjeljko Fabrio. Set in the borderlands of Dalmatia and Kvarner, Fabrio’s novels evoke the lives of people belonging to different ethnic and speech communities – Croats, Italians, Austrians, Serbs, Yugoslavs, or as yet to be defined individuals – from the beginning of the 19th c. until today. Staging ‘weak protagonists’ rather than ‘strong heroes’ and inclining to sociolects and dialects rather than to standard language, his novels create a universe in which the characters’ individual experience counters Croatian national narratives. Fabrio’s narratives suggest that multilingual settings might either lead to conflicts between ethnic groups or to reconciliation between them. Ignoring social rules, individuals join other communities, moving up and down the class ladder. Such mésalliances result in complex genealogical trees out of which a hybrid culture emerges. Through allegorical transfer, the author signals the possibility of reconciliation between different conflicted communities.
Du français médiévaltravail(lier)à l’anglaistravel: parcours d’un régionalisme sémantique
Authors: Bragantini-Maillard Nathalie 
Published: November 2022

AbstractThe lexemetravail(lier), well-known in Medieval French, pertains in limited use to the notion of travel, in the specific sense of ʻ(to) travelʼ. Our work shows that this precise meaning could be identified as a regionalism that first appeared in Anglo-Norman during the second half of the 12thcentury, quickly spreading on the continent to the other regional areas of the Oïl territory. Adopted in Middle English by the end of the 13thcentury, it survives in Modern English astraveland its derivatives. The present paper recounts the journey of this semantic regionalism during the past centuries, establishes a syntactic-semantic synthesis of its different uses and formulates a hypothesis on the modalities of its origin.
The eschatological afterlife and the soul’s immortality in Berceo’s “El prior y el sacristán”
Authors: Riva Fernando 
Published: November 2022

AbstractThis study proposes that Gonzalo de Berceo’s “El prior y el sacristán”, the twelfth miracle in the collection known asMilagros de Nuestra Señora, is a rejection of heretical beliefs based on interpretations of Aristotelian thought, which flourished throughout Europe in the thirtheenth century. These ideas, for example, questioned the immortality of the soul as proposed by rationalists thinkers who were heavily influenced by Aristotelian philosophy in an interpretation following Averroes’s commentaries, which started being translated into Latin in the first half of the thirtheenth century. Aristotelian ideas, particularly those derived from thelibri naturales, were condemned as early as 1210 and 1215, when the Iberian origin of some of their protagonists were explicitly addressed by Parisian ecclesiastical authorities. Berceo’s response, based on Augustinian ideas on the soul’s life after death, is an indication of the Iberian participation in a broader discourse against Aristotelianism. Thus, “El prior y el sacristán” situates Berceo’s work in the larger European context of the thirtheenth century. Finally, Berceo’s main point of departure for his response is found in eschatology, which he elaborates following Julian of Toledo’sPrognosticon futuri saeculi(c. 688).
El clítico femenino la/las en las expresiones lexicalizadas del español: nueva propuesta de análisis diacrónico
Authors: Wang Ziwen 
Published: November 2022

Abstract
This paper deals with a set of idiomatic expressions in Spanish which typically display a non-referential feminine clitic la/las as a constituent (e.g. pasarla bien ‘to have a good time’). In opposition to the conventional mainstream theories, which account for the non-referential status of this clitic by the ellipsis of a previously existing feminine NP (e.g. cosa, ocasión), I will argue that this lexicalized feminine clitic la/las can be diachronically related to the Latin neuter plural demonstrative illa denoting abstract discourse referents, and thus its apparent non-referentiality should be viewed as a kind of global anaphor. On the basis of Ojeda (1993)’s Mereological Taxonomy of Kinds and the typological evidence reported by Espinal (2009), I will suggest that in these constructions the feminine clitic la/las expresses the so-called «conceptional neuterality» and is semantically equivalent to the neuter lo (e.g. pasarlo
/
la bien). Lastly, following Loporcaro’s work on the evolution of the Latin neuter in Romance languages (2018), I will defend that the Latin neuter plural demonstratives (ea, haec, ista, illa) survived into early Hispano-Romance and were preserved in lexicalized constructions due to high token frequency, as also evidenced by additional cross-linguistic data from other Romance languages.
Os Lusíadas, 1572: the exemplars and the editions
Authors: Penafiel André B. 
Published: November 2022

Abstract
The first edition of Os Lusíadas, by Luís de Camões, has long attracted the attention of scholars, and its surviving copies are mysterious objects. Over the years, different hypotheses have been proposed and a range of methodologies employed, in attempts to explain their mysteries. This study is based on the analysis of twenty-five copies, applying techniques from the field of material bibliography. Using mechanical collation, it argues that two different editions were printed, bearing the same date. It proposes a classification system and terminology, which affects the editions, the copies and the sheets which constitute each copy. This study seeks to make an initial contribution to the ongoing debate on the number of editions dated 1572; further observations, which could make the ultimate answer more nuanced, will be published in future.
Elementi orientali nelle lettere di Andrea Berengo (1553–1556)
Authors: Schweickard Wolfgang 
Published: November 2022

AbstractThe letters of the Venetian merchant Andrea Berengo, written in the mid-16th century, are not only a precious testimony of Venetian commercial history, but also a particularly rich source for linguistic and lexicographic studies on Renaissance Venetian. The present paper examines selected oriental elements of Arabic, Turkish and Persian origin from the point of view of historical lexicography. The special linguistic interest of Berengo's letters is confirmed by the fact that most of the terms studied are early or even first attestations in Italian.