bluuebunny/crossref_metadata_2025_split huggingface dataset:
Labour Force Projections in India Until 2060 and Implications for the Demographic Dividend
Authors: Marois Guillaume , Zhelenkova Ekaterina , Ali Balhasan 
Published: June 2022

AbstractWhile India is entering the period of demographic dividend, female labour participation rates remain very low. This paper aims to provide the very first labour force projections for India and its regions up to the year 2060. Projections are achieved using a discrete-time microsimulation model in which changes in population size and composition come from the interaction between demographic characteristics, educational attainment, and secular tendencies. Labour force participation rates are estimated at the individual level using personal characteristics as predictors. Results show that under constant labour force participation rates, the labour force dependency ratio (non-workers/workers) is very unlikely to attain favourable levels, which compromises the potential demographic dividend that the country could gain from its favourable age-structure. At the subnational level, the forecast yields the most favourable dependency ratio in 2060 in the regions that combine both a low-age dependency ratio and a higher participation of women. Results moreover suggest that female labour force participation is a better driver of the labour force dependency ratio than the age composition.
A new parasitic copepod (Copepoda; Cyclopoida; Chondracanthidae) from two pomacentrid fishes caught on the Great Barrier Reef, Queensland, Australia
Authors: Boxshall Geoff A. 
Published: June 2022

AbstractA new species of the copepod genus Pseudacanthocanthopsis Yamaguti & Yamasu, 1959 (family Chondracanthidae) is described based on material of both sexes collected from two pomacentrid host fishes caught off Lizard Island, Queensland. The type host is Neopomacentrus azysron (Bleeker) and the additional host is N. cyanomos (Bleeker). The new species is distinguishable from all congeners by the form of the antennule of the female, which is dorso-ventrally flattened and extends out anteriorly to the front of the cephalothorax margin.
Lead (Pb) Contamination in Agricultural Products and Human Health Risk Assessment in Bangladesh
Authors: Kumar Sazal , Islam Rafiquel , Akash Pritom Bhowmik , Khan Md Hafijur Rahaman , Proshad Ram , Karmoker Joyanto , MacFarlane Geoff R. 
Published: June 2022

AbstractLead (Pb) is a widely occurring heavy metal employed in industrial products and hence released into the environment, causing several environmental health risk concerns. This study comprehensively surveyed the literature on Pb contamination in different agricultural foods and food products commonly consumed by Bangladeshi inhabitants and assessed associated cancer and non-cancer health risks. Cereals (i.e., rice, wheat and maize) contained very high concentrations of Pb among the selected food items, the highest was found in wheat (4.04 µg g−1), while rice and maize were 2.22 and 1.43 µg g−1, respectively, that exceeded the maximum allowable concentration (MAC, 0.20 µg g−1) for cereals. Vegetables contained higher Pb than the MAC of 0.01 µg g−1, except for mushroom, green banana, cauliflower and arum. In addition, pulses also contained a moderate amount of Pb; however, fruits contained a low level of Pb, except for mangoes. When examining spatial differences in Pb contamination, most districts exhibited high Pb content in cereals; however, vegetables of the Tangail district exhibited the highest Pb concentrations (2.17 µg g−1), originating from industrial operations and vehicular emissions. In terms of human health risk assessment, it was observed that consumption of rice, zucchini, tesla gourd, sponge gourd, okra, drumstick lib, chili and cabbage might pose non-cancer health risks (THQs > 1); however, fruits and pulses do not pose any non-cancer health risks to Bangladeshi residents. Most of the cereals and vegetables showed a higher value than 10−6, indicating a potential cancer risk; however, fruits and pulses showed lower risk only marginally exceeding the lower allowable limit (i.e., 10−6).
Graphical abstract
Game playing and fluctuations in emotional climate
Authors: Bonne Linda , Higgins Joanna 
Published: June 2022

AbstractThe inclusion of games in mathematics programmes is widely believed to foster the enjoyment of mathematics. The focus of this paper is on fluctuations in emotional climate during the playing of whole-class mathematics games. A multimethod approach drawing on the sociology of emotions was employed to explore changes in the classroom emotional climate that were associated with game playing. The event-oriented inquiry was conducted with two teachers and a class of 10- to 13-year-olds in a New Zealand classroom during mathematics sessions. Over a series of eight mathematics lessons, there were three noticeable fluctuations in emotional climate, all of which occurred during whole-class games. Our analysis of these three events identified a successful interaction with dramatic emotional energy associated with a positive emotional climate, a successful interaction with undramatic emotional energy associated with positive emotional climate, and an unsuccessful interaction associated with negative emotional climate with interactional repair. The third event also illustrated how the incomplete nature of a game’s rules can provide an opportunity for a negative emotional climate to be associated with game playing. The taken-for-granted wisdom that whole-class mathematics games can enhance emotional aspects of a classroom learning environment is supported by some of our evidence.
Musculoskeletal Deficits and Cognitive Impairment: Epidemiological Evidence and Biological Mechanisms
Authors: Sui Sophia X. , Balanta-Melo Julián , Pasco Julie A. , Plotkin Lilian I. 
Published: June 2022

Abstract
Purpose of Review
Cognitive impairment is associated with obesity, sarcopenia, and osteoporosis. However, no critical appraisal of the literature on the relationship between musculoskeletal deficits and cognitive impairment, focusing on the epidemiological evidence and biological mechanisms, has been published to date. Herein, we critically evaluate the literature published over the past 3 years, emphasizing interesting and important new findings, and provide an outline of future directions that will improve our understanding of the connections between the brain and the musculoskeletal system.

Recent Findings
Recent literature suggests that musculoskeletal deficits and cognitive impairment share pathophysiological pathways and risk factors. Cytokines and hormones affect both the brain and the musculoskeletal system; yet, lack of unified definitions and standards makes it difficult to compare studies.

Summary
Interventions designed to improve musculoskeletal health are plausible means of preventing or slowing cognitive impairment. We highlight several musculoskeletal health interventions that show potential in this regard.
A Comprehensive Review on Grape Juice Beverage in Context to Its Processing and Composition with Future Perspectives to Maximize Its Value
Authors: Kersh Dina M. El , Hammad Ghada , Donia Marwa S. , Farag Mohamed A. 
Published: June 2022

AbstractRed and purple grape juices (GJs) have long been consumed worldwide for their unique taste and nutritive value. Moreover, grape is postulated to play an important role in the improvement of cardiovascular risk factors owing to its rich polyphenol content. Little is known regarding GJ’s holistic chemistry and functionality as compared to those of other fruit juices. This review aims to compile the state-of-the art chemistry of colored grape juices and in context to its analysis and nutritional values. Further, a review of potential contaminants to be introduced during manufacturing and other factors that influence juice quality and or health effects are presented to help maximize GJ’s quality. A comparison between analytical methods for juice QC establishment is presented employing hyphenated platforms versus direct spectroscopic techniques. The enrichment of the colored skin with a myriad of phenolics poses it as a functional beverage compared to that of skinless juice.Graphical abstract
Happy to belong: Exploring the embeddedness of well-being in the integration of migrant and refugee minors
Authors: Bajo Marcos Eva , Fernández Mercedes , Serrano Inmaculada 
Published: June 2022

Abstract
This paper aims to explore the role of Child Well-Being (CWB) in the integration processes of migrant and refugee minors. Through the co-creative development of a new child-centered system of indicators about the integration of migrant and refugee children in Europe the authors discuss a) the prominent role of well-being in this set of indicators, and b) how reappraising these indicators from a well-being approach can contribute to delving into which aspects of CWB are connected to the integration of migrant children. The contributions of this paper open new research paths: on the one hand, the methodology presented provides a reference for future research that can replicate the procedure to build child-centered indicators in disciplines different than migration studies; on the other hand, the results presented suggest not only that well-being has a prominent role in migrant children integration experiences, but also, that reappraising dimensions of migrant children’s integration from a well-being approach hints at blurry borders between both concepts. This suggests promising research opportunities to underpin the relationship between integration and well-being.
Public auditing for real-time medical sensor data in cloud-assisted HealthIIoT system
Authors: Ye Weiping , Wang Jia , Tian Hui , Quan Hanyu 
Published: June 2022

AbstractWith the advancement of industrial internet of things (IIoT), wireless medical sensor networks (WMSNs) have been widely introduced in modern healthcare systems to collect real-time medical data from patients, which is known as HealthIIoT. Considering the limited computing and storage capabilities of lightweight HealthIIoT devices, it is necessary to upload these data to remote cloud servers for storage and maintenance. However, there are still some serious security issues within outsourcing medical sensor data to the cloud. One of the most significant challenges is how to ensure the integrity of these data, which is a prerequisite for providing precise medical diagnosis and treatment. To meet this challenge, we propose a novel and efficient public auditing scheme, which is suitable for cloud-assisted HealthIIoT system. Specifically, to address the contradiction between the high real-time requirement of medical sensor data and the limited computing power of HealthIIoT devices, a new online/offline tag generation algorithm is designed to improve preprocessing efficiency; to protect medical data privacy, a secure hash function is employed to blind the data proof. We formally prove the security of the presented scheme, and evaluate the performance through detailed experimental comparisons with the state-of-the-art ones. The results show that the presented scheme can greatly improve the efficiency of tag generation, while achieving better auditing performance than previous schemes.
Graphical abstract
Empagliflozin mitigates type 2 diabetes-associated peripheral neuropathy: a glucose-independent effect through AMPK signaling
Authors: Abdelkader Noha F. , Elbaset Marawan A. , Moustafa Passant E. , Ibrahim Sherehan M. 
Published: June 2022

AbstractDiabetic peripheral neuropathy (DPN) represents a severe microvascular condition that dramatically affects diabetic patients despite adequate glycemic control, resulting in high morbidity. Thus, recently, anti-diabetic drugs that possess glucose-independent mechanisms attracted attention. This work aims to explore the potentiality of the selective sodium-glucose cotransporter-2 inhibitor, empagliflozin (EMPA), to ameliorate streptozotocin-induced DPN in rats with insight into its precise signaling mechanism. Rats were allocated into four groups, where control animals received vehicle daily for 2 weeks. In the remaining groups, DPN was elicited by single intraperitoneal injections of freshly prepared streptozotocin and nicotinamide (52.5 and 50 mg/kg, respectively). Then EMPA (3 mg/kg/p.o.) was given to two groups either alone or accompanied with the AMPK inhibitor dorsomorphin (0.2 mg/kg/i.p.). Despite the non-significant anti-hyperglycemic effect, EMPA improved sciatic nerve histopathological alterations, scoring, myelination, nerve fibers’ count, and nerve conduction velocity. Moreover, EMPA alleviated responses to different nociceptive stimuli along with improved motor coordination. EMPA modulated ATP/AMP ratio, upregulated p-AMPK while reducing p-p38 MAPK expression, p-ERK1/2 and consequently p-NF-κB p65 as well as its downstream mediators (TNF-α and IL-1β), besides enhancing SOD activity and lowering MDA content. Moreover, EMPA downregulated mTOR and stimulated ULK1 as well as beclin-1. Likewise, EMPA reduced miR-21 that enhanced RECK, reducing MMP-2 and -9 contents. EMPA’s beneficial effects were almost abolished by dorsomorphin administration. In conclusion, EMPA displayed a protective effect against DPN independently from its anti-hyperglycemic effect, probably via modulating the AMPK pathway to modulate oxidative and inflammatory burden, extracellular matrix remodeling, and autophagy.
Diagnostic performance of dedicated breast positron emission tomography
Authors: Hashimoto Rikako , Akashi-Tanaka Sadako , Watanabe Chie , Masuda Hiroko , Taruno Kanae , Takamaru Tomoko , Ide Yoshimi , Kuwayama Takashi , Kobayashi Yasuhiro , Takimoto Masafumi , Nakamura Seigo 
Published: June 2022

Abstract
Background
Dedicated breast positron emission tomography (dbPET) has been developed for detecting smaller breast cancer. We investigated the diagnostic performance of dbPET in patients with known breast cancer.

Methods
Eighty-two preoperative patients with breast cancer were included in the study (84 tumours: 11 ductal carcinomas in situ [DCIS], 73 invasive cancers). They underwent mammography (MMG), ultrasonography (US), and contrast-enhanced breast magnetic resonance imaging (MRI) before whole-body PET/MRI (WBPET/MRI) and dbPET. We evaluated the sensitivity of all modalities, and the association between the maximum standard uptake value (SUVmax) level and histopathological features.

Results
The sensitivities of MMG, US, MRI, WBPET/MRI and dbPET for all tumours were 81.2% (65/80), 98.8% (83/84), 98.6% (73/74), 86.9% (73/84), and 89.2% (75/84), respectively. For 11 DCIS and 22 small invasive cancers (≤ 2 cm), the sensitivity of dbPET (84.9%) tended to be higher than that of WBPET/MRI (69.7%) (p = 0.095). Seven tumours were detected by dbPET only, but not by WBPET/MRI. Five tumours were detected by only WBPET/MRI because of the blind area of dbPET detector, requiring a wider field of view. After making the mat of dbPET detector thinner, all 22 scanned tumours were depicted. The higher SUVmax of dbPET was significantly related to the negative oestrogen receptor status, higher nuclear grade, and higher Ki67 (p < 0.001).

Conclusions
The sensitivity of dbPET for early breast cancer was higher than that of WBPET/MRI. High SUVmax was related to aggressive features of tumours. Moreover, dbPET can be used for the diagnosis and oncological evaluation of breast cancer.
Pulled fly balls are harder to catch: a game analysis with a machine learning approach
Authors: Kato Mamiko , Yanai Toshimasa 
Published: June 2022

AbstractTwo hypotheses were tested: (1) the deflecting motion of fly balls caused by aerodynamic effects varies between the pull side and opposite side of the fair territory, and (2) the probability of flyout is lower on the pull side than the opposite side in Japan’s professional baseball games. From all radar-tracking outputs of official games in 2018–2019, fly balls that resulted in outs or base hits were selected for analysis (N = 25,413), and indices representing horizontal and vertical deflecting motions of fly balls were computed and compared between the pull side and opposite side. A machine learning algorithm was used to construct a model to predict the probability of flyout from the kinematic characteristics of fly balls. Flyout zones where the probability of flyout was > 0.6 were computed for a systematically constructed set of fly balls having identical distribution between the pull side and opposite side. The results showed that: (1) most fly balls landing on the opposite side deflected in the same direction whereas the pulled fly balls deflected to either direction, (2) the pulled low fly balls had greater variability in the deflecting motions than the opposite side counterpart, (3) overall probability of flyout of the low fly balls was lower in the pull side (0.41) than the opposite side (0.49), and (4) the flyout zone of an outfielder in the pull side (mean = 698 m2) for low fly balls was smaller than that of the others (≥ 779 m2). The hypotheses were supported. The pulled low fly balls had substantial variations in the direction and magnitude of deflections, which might have reduced the flyout zone on the pull side.
Feasibility analysis of GNSS-based navigation for LUMIO mission
Authors: Bernelli-Zazzera Franco , Forte Danilo 
Published: June 2022

AbstractThe paper presents the design of a realistic model of the GNSS constellations GPS and Galileo to perform a navigation performances analysis in lunar environment. Starting from the visibility analysis, the link-budget of each visible GNSS spacecraft is estimated using for each one realistic data for the transmitted power and environmental and system parameters. The navigation performances are evaluated in this scenario. The model implemented is applied to the trajectory of the LUMIO CubeSat mission and the results are commented. LUMIO is a lunar CubeSat mission, on a Halo orbit at the L2 point of the Earth–Moon system, designed to observe the measured meteoroid impacts on the far side of the Moon. LUMIO has been designed to perform autonomous onboard navigation with an accuracy better than 30 km for more than 99.7% of the time. The navigation analysis in this work can be compared to such a requirement to evaluate if a GNSS-based navigation solution could be employed as well.
Hypersonic retro propulsion for reusable launch vehicles tested in the H2K wind tunnel
Authors: Marwege Ansgar , Kirchheck Daniel , Klevanski Josef , Gülhan Ali 
Published: June 2022

AbstractIn the frame of the RETALT (RETro propulsion Assisted Landing Technologies) project, the aerodynamics of reusable launch vehicles reentering the atmosphere and descending and landing with the aid of retro propulsion are studied. In particular, series of wind tunnel tests are performed to assess the aerodynamic properties of such a vehicle in the various flight phases from hypersonic and supersonic re-entry down to subsonic conditions at touch down. This paper discusses the results of wind tunnel tests in the Hypersonic Wind Tunnel Cologne (H2K) at the Supersonic and Hypersonic Flow Technologies Department of the German Aerospace Center (DLR) in Cologne for the hypersonic retro propulsion maneuver during the re-entry burn. Mach numbers of 5.3 and 7.0 were tested with a variation of thrust coefficient, Reynolds number, angle of attack, cold and heated air. A single-engine configuration and a configuration with three active engines were tested. In all tests, the engine exhaust was simulated using ambient temperature or heated air. Dependencies of the flow features of the square root of the thrust coefficient known from literature for the single-engine case can be confirmed and extended to the three-engine configuration. For the single-engine case, the formation of vortex rings was observed, which eventually leads to strong individual vortices and extensive flow field disturbances. The heating of the supply air up to 600 K mitigates condensation in the retro plume, while the overall flow structures remained unchanged. High thrust coefficients generally lead to vanishing pressure coefficients on the engine bay. The single and the three-engine cases are comparable in this sense. The Mach number and Reynolds number are of subordinate importance for the pressures on the vehicle, while the thrust coefficient is the dominating similarity parameter. Pressure coefficients far downstream of the retro plume are affected less and, therefore, are not negligible at non-zero angles of attack. In this paper, the methodology of the wind tunnel tests and the results obtained are described in detail.
CD155 promotes radioresistance and malignancy of esophageal cancer by regulating Hippo-YAP pathway
Authors: Xin Huixian , Liu Yuchen , Chen Pengxiang , Yin Tianwen , Wang Meijie , Liu Tianyu , Wen Zhihua , Cheng Yufeng 
Published: June 2022

AbstractThe expression of CD155 has been observed to increase in various human cancers, but its role in the development of esophageal cancer (EC) is unclear. Radiotherapy is one of the primary therapeutic options for EC. However, radioresistance is still a severe issue in EC treatment. In this study, Oncomine database mining, immunohistochemistry, and survival analysis showed that higher expression of CD155 in patients with EC than in healthy controls. In vitro and in vivo, we found for the first time that irradiation increased the expression of CD155 in EC cells. CD155 knockdown inhibited cell proliferation and migration and tumor formation, and significantly increased radiosensitivity in EC. The in vivo model with high CD155 expression significantly promoted the proliferation and migration of EC cells. Furthermore, increased CD155 expression was associated with poor prognosis in patients with EC. CD155 regulated the Hippo-Yap pathway, influencing cell proliferation and migration. Therefore, CD155 is essential for the proliferation, migration, and radioresistance of EC. CD155 inhibition may be a viable strategy for improving radiation treatment efficacy in individuals with EC.
Effects of Fins Base Rounding on Heat Transfer Characteristics of Absorber Tube of Parabolic Trough Collector
Authors: Fatouh M. , Saad Nourhan , Abdala Antar M. M. 
Published: June 2022

AbstractIn this study, the heat transfer characteristics of an improved absorber tube of parabolic trough solar collector LS-2 are investigated using ANSYS software. Oil syltherm 800 type is used as a heat transfer fluid. Three types of absorber tubes are tested; the first is a smooth tube and the others are finned tubes. One of the rough cases is rectangular cross-section fins with rounding at fin base and the other does not have rounding at fin base. Simulations are performed with fin thickness variations of 2, 4 and 6 mm. The fin lengths change at 5, 10, 15, 20 and 25 mm. The radii of rounding are 2, 3 and 4 mm and angles between fins are 45° and 90°. Wide range of operating parameters is considered, such as inlet fluid temperatures (300:600 K), flow rate (6:24 m3/h) and direct normal irradiance (500:1000 W/m2). The thermal efficiency, Nusselt number and thermal enhancement index are calculated under different operating conditions. The results show that thermal enhancement index of the fin with round edge radius of 4 mm is higher than that of the fin with the sharp edge (R = 0 mm) by about 10.74% under the considered conditions. The thermal enhancement index of the round edge fins with a length of 25 mm is nearly 25.6% higher than that of the round edge fins with a length of 5 mm. At a fin thickness of 6 mm, the thermal enhancement index of the round edge fin is nearly 7.8% higher than that of the sharp edge fin. At 45° angle and 25-mm fin length, the thermal enhancement index for round and sharp-edged fins is 1.644 and 1.532, respectively. When the inlet fluid temperature increased from 300 to 600 K, the heat enhancement index value increased by 14.57%; as the flow rate increased from 6 to 12 m3/h, the heat enhancement index value decreased by 11.63%. The thermal enhancement index increased from 1.265 to 1.359 as the direct normal irradiance varied from 500 to 700 W/m2.