bluuebunny/crossref_metadata_2025_split huggingface dataset:
An electrochemical sensor based on electrospun MoS2@SnO2 modified carbon nanofiber composite materials for simultaneously detection of phenacetin and indomethacin
Authors: Hu Weijuan , Lu Huan , Duan Yingchun , Li Li , Ding Yaping , An Jiangxue , Duan Dingding 
Published: January 2022

AbstractSnO2‐CNF was prepared by coaxial blending technology, and MoS2 was grown uniformly on SnO2‐CNF composite by adding a hydrothermal post‐treatment step. The uniform distribution of MoS2 on one‐dimensional SnO2‐CNF can effectively establish a layered three‐dimensional structure. Accordingly, the prepared MoS2‐coated SnO2‐CNF composite material has higher surface area and more active sites to obtain better electrochemical performance. We constructed an electrochemical sensor within the composite material with enhanced performance to realize the simultaneous and highly sensitive detection of phenacetin and indomethacin. The sensor has linear ranges of 0.050–7200 μM and 0.05–500 μM, respectively, and the detection limits were 0.016 μM and 0.013 μM. Furthermore, the sensor has good anti‐interference ability and stability, which also achieves good recovery rate in the actual sample detection.
Sensitivity and Selectivity Analysis of Fluorescent Probes for Hydrogen Sulfide Detection
Authors: Zhou Yingzhu , Mazur Federico , Liang Kang , Chandrawati Rona 
Published: January 2022

AbstractHydrogen sulfide (H2S) is a gasotransmitter known to regulate physiological and pathological processes. Abnormal H2S levels have been associated with a range of conditions, including Parkinson's and Alzheimer's diseases, cardiovascular and renal diseases, bacterial and viral infections, as well as cancer. Therefore, fast and sensitive H2S detection is of significant clinical importance. Fluorescent H2S probes hold great potential among the currently developed detection methods because of their high sensitivity, selectivity, and biocompatibility. However, many proposed probes do not provide a gold standard for proper use and selection. Consequently, issues arise when applying the probes in different conditions. Therefore, we systematically evaluated four commercially available probes (WSP‐1, WSP‐5, CAY, and P3), considering their detection range, sensitivity, selectivity, and performance in different environments. Furthermore, their capacity for endogenous H2S imaging in live cells was demonstrated.
Catalytic Hydroboration and Reductive Amination of Carbonyl Compounds by HBpin using a Zinc Promoter
Authors: Kumar Ravi , Rawal Parveen , Banerjee Indrani , Pada Nayek Hari , Gupta Puneet , Panda Tarun K. 
Published: January 2022

AbstractThe chemoselective hydroboration of aldehydes and ketones, catalyzed by Zinc(II) complexes [κ2‐(PyCH=NR)ZnX2] [R=CPh3, X=Cl (1) and R=Dipp (2,6‐diisoropylphenyl) and X=I (2)], in the presence of pinacolborane (HBpin) at ambient temperature and under solvent‐free conditions, which produced the corresponding boronate esters in high yield, is reported. Zinc metal complexes1and2were derived in 80–90% yield from the reaction of iminopyridine [PyCH=NR] with anhydrous zinc dichloride in dichloromethane at room temperature. The solid‐state structures of both zinc complexes were confirmed using X‐ray crystallography. Zinc complex1was also used as a competent pre‐catalyst in the reductive amination of carbonyl compounds with HBpin under mild and solvent‐free conditions to afford a high yield (up to 97%) of the corresponding secondary amines. The wider substrate scope of both reactions was explored. Catalytic protocols using zinc as a pre‐catalyst demonstrated an atom‐economic and green method with diverse substrates bearing excellent functional group tolerance. Computational studies established a plausible mechanism for catalytic hydroboration.
Intergenerational trauma: Parental PTSD and parent‐reported child abuse subtypes differentially relate to admission characteristics in the autism inpatient collection
Authors: McDonnell Christina G. , Andrzejewski Theresa , Dike Janey 
Published: January 2022

AbstractAutistic youth experience high rates of maltreatment. Little research has considered how distinct abuse dimensions differentially relate to meaningful outcomes, nor taken an intergenerational approach to consider how caregiver trauma and child maltreatment are related. This study sought to identify how parent‐reported child abuse subtypes and parent posttraumatic stress disorder (PTSD) relate to each other and to admission characteristics upon inpatient service entry. Autistic youth (N = 527; 79% White, 21.3% girls, mean age = 12.94 years) participated in the autism inpatient collection. Parents reported on child abuse subtypes (physical, sexual, emotional) and their own PTSD, child behavior and emergency services, and parenting stress. Youth of parents with PTSD were nearly three times more likely to have parent‐reported physical and emotional abuse. Autistic girls were more likely to experience parent‐reported sexual abuse and a higher number of subtypes. Lower income related to higher rates of parent‐reported child emotional abuse and parent PTSD. Emotional abuse associated with child behavior whereas both child physical and emotional abuse related to emergency services. Reported parent PTSD associated with child behavior and parental distress. When considered jointly, parent PTSD and number of parent‐reported child abuse subtypes differentially related to child behavior and interacted to predict psychiatric hospitalizations. Intergenerational continuity of trauma is important to consider among autistic youth, and both parent‐reported child abuse and parent PTSD relate to admission characteristics. Critical limitations include reliance on binary parent reports of child abuse and parent PTSD and the low representation of youth of minoritized identities. Implications for trauma‐informed care are discussed.Lay summaryAutistic youth whose parents had reported posttraumatic stress disorder (PTSD) were nearly three times more likely to have experienced parent‐reported physical and emotional abuse. Parent‐reported child emotional abuse uniquely related to child behavioral concerns whereas both physical and emotional abuse related to higher emergency services. Parent PTSD also related to admission characteristics, showing that intergenerational continuity of trauma is critical to consider for understanding child maltreatment among autistic youth.
Emotion and intergroup cooperation: How verbal expressions of guilt, shame, and pride influence behavior in a social dilemma
Authors: Nunney Samuel J. , van der Schalk Job , Manstead Antony S. R. 
Published: January 2022

AbstractIn interpersonal relations, it is known that expressing self‐conscious emotions such as guilt and shame following a transgression is beneficial to reconciliation. In the current research, we examine whether this also applies to intergroup relations. Groups of three persons played an intergroup version of the “centipede game,” in which one party can cooperate with or exploit another party. In Study 1, two groups played six rounds of this game in each of two phases. Between phases, groups rated how much guilt, shame, and pride they experienced in relation to how they had performed in Phase 1; these ratings were shared with the opposing group. Groups expressing high levels of guilt and shame were associated with greater cooperation in Phase 2, whereas groups expressing high levels of pride were associated with lower cooperation in Phase 2. In Study 2, all groups played against a “group” programmed to behave in an exploitative way in Phase 1. This group then expressed shame, pride, or no emotion (control) about its performance. Cooperation in Phase 2 was significantly higher in the shame than in the pride condition, and altruistic punishment was highest in the pride condition and lowest in the shame condition. Between them, these studies show that emotional expression plays an important role in repairing intergroup relationships and in particular that expressing shame about a transgression enhances intergroup cooperation following a transgression.
Effectiveness of olanzapine in the treatment of anorexia nervosa: A systematic review and meta‐analysis
Authors: Han Ruijun , Bian Qingtao , Chen Hao 
Published: January 2022

AbstractObjectiveAnorexia nervosa (AN) is a severe psychiatric disorder characterized by starvation and malnutrition, a high incidence of coexisting psychiatric conditions, and treatment resistance. The effect of pharmacotherapy has been controversial.MethodA systematic review was conducted for evidence of an effect of olanzapine versus placebo in adults or its effect as adjuvant treatment of AN in adolescents.ResultsA total of seven articles (304 patients with AN) were identified. There were four double‐blind, randomized studies examining the effect of olanzapine in the treatment of AN. The mean difference in body mass index (BMI) at the end of treatment between olanzapine and placebo was 0.67 kg/m2 (95% confidence interval (CI) 0.15–1.18 kg/m2; p = 0.01; I2 = 0%, p for heterogeneity < 0.79). The olanzapine groups showed a significant increase in BMI of 0.68 kg/m2 (95% CI 0.22–1.13 kg/m2; p < 0.001; I2 = 0%, p for heterogeneity = 0.74) compared to the placebo groups. Only two studies examined the effect of olanzapine as adjuvant treatment in adolescents and showed an increase in BMI of 0.66 kg/m2 (95% CI −0.36 to 1.67 kg/m2; p = 0.21; I2 = 11%, p for heterogeneity = 0.32).DiscussionOlanzapine showed efficacy in the treatment of AN with an increased BMI at the end of treatment in adults. The effect of olanzapine as adjuvant treatment in adolescents remains unclear.
Collaboration and advance planning across campus create more cybersecure colleges, universities
Authors: Bannister Mary 
Published: January 2022

“Cybersecurity is a threat that changes all the time, so addressing it involves everybody living and breathing security as second nature.” This was a key theme of the recent National Student Clearinghouse webinar titled “CyberSecurED: Building a Cyber‐Ready Campus.” The webinar panelists — experts from EDUCAUSE, the Cyber Readiness Institute, REN‐ISAC: Research and Education Networks Information Sharing and Analysis Center, and NSC — discussed best practices for preventing and responding to cyber‐attacks.
Scalable Syntheses and Biological Evaluation of Africane‐Type Sesquiterpenoids
Authors: Matsuda Yutaka , Koyama Takayuki , Kawano Sayaka , Miura Kazuki , Simizu Siro , Saikawa Yoko , Nakata Masaya 
Published: January 2022

AbstractPractical total syntheses of africane‐type sesquiterpenoids were realized by reexamination of a divergent strategy employing optimized three‐component coupling followed by ring‐closing metathesis and substrate‐controlled cyclopropanation. This sequential eight‐step conversion provided Δ9(15)‐africanene, a common bicyclo[5.3.0]decane intermediate for the syntheses of africane derivatives, in more than twice the yield as in the previous approach. The scalability and robustness of this improved synthetic route were confirmed by gram‐scale preparation of Δ9(15)‐africanene. In vitro cell‐based assays of the synthesized africane‐type sesquiterpenoids disclosed that ester‐incorporating derivatives showed cytotoxic activity against HeLa cells. The effect of relative and absolute configuration of africane‐9,15‐diol monoacetates on the cytotoxicity against HeLa cells was also investigated.
Antischistosomal Activity of Essential Oils: An Updated Review
Authors: Oliveira Thaís A. S. , Pagotti Mariana C. , Magalhães Lizandra G. , Crotti Antônio E. M. 
Published: January 2022

AbstractThis review article covers literature on the antischistosomal activity of essential oils (EOs) between 2011 and 2021. Criteria for classifying results from in vitro schistosomicidal assays are proposed for the first time. Parameters to evaluate the in vitro antischistosomal potential of EOs other than their ability to cause the death of Schistosoma mansoni adult worms (e. g., couple separation, egg laying, and egg development inhibition) are also addressed and discussed.
Five‐year outcomes of transcatheter mitral valve implantation and redo surgery for mitral prosthesis degeneration
Authors: Simard Trevor , Lloyd James , Crestanello Juan , Thaden Jeremy J. , Alkhouli Mohamad , Guerrero Mayra , Rihal Charanjit S. , Eleid Mackram F. 
Published: January 2022

AbstractBackgroundTranscatheter mitral valve replacement (TMVR) has emerged as a feasible alternative to redo surgical mitral valve replacement (SMVR) in patients with degenerated mitral prostheses, with limited comparative data.MethodsWe compared mid‐term outcomes in patients with degenerated mitral valve prostheses treated with TMVR or redo SMVR. The primary endpoint was survival at 5 years of follow‐up.ResultsFrom 2014 to 2020, 215 patients presented with degenerated mitral valve prostheses. Of whom 86 (40%) were treated with TMVR (75[87%] valve‐in‐valve and 11[13%] valve‐in‐ring), while 129 patients (60%) underwent SMVR. The TMVR cohort was older (p < 0.0001), more symptomatic (p = 0.0003) and had more chronic lung disease (p = 0.02), worse renal function (p = 0.02) and higher right ventricular systolic pressures (p < 0.0001). Thirty‐day mortality was lower with TMVR versus SMVR (2.4% vs. 10.2%, OR4.69 [95% CI 1.25–30.5], p = 0.04) with probability of mortality at 1, 2, and 5 years being 14.7% versus 17.5%, 24.5% versus 20.7%, and 49.9% versus 34.0%, respectively. Mode of prosthesis degeneration, baseline hemodynamics, and valve selection did not appreciably impact outcomes.ConclusionsTMVR for degenerated mitral prostheses is associated with better early survival compared to SMVR despite a greater burden of comorbidities. In contrast, 5 year survival rates appear more favorable with SMVR, which may reflect the lower baseline risk of this population. Clinical, hemodynamic, and echocardiographic follow‐up support the mid‐term durability of TMVR for degenerated mitral prostheses. Further dedicated studies, however, are required to optimize outcomes in this challenging patient cohort and to navigate the choice of approach for each individual patient.
Prevalence and clinical impact of high platelet reactivity in patients with chronic kidney disease treated with percutaneous coronary intervention: An updated systematic review and meta‐analysis
Authors: Mangiacapra Fabio , Paolucci Luca , Viscusi Michele M. , Mangiacapra Roberto , Ferraro Pietro M. , Nusca Annunziata , Melfi Rosetta , De Luca Leonardo , Gabrielli Domenico , Ussia Gian P. , Grigioni Francesco 
Published: January 2022

AbstractBackgroundHigh platelet reactivity (HPR) on clopidogrel and chronic kidney disease (CKD) are recognized as potent risk factors for adverse outcomes in patients suffering coronary artery disease (CAD) and undergoing percutaneous coronary intervention (PCI). However, conclusive evidence regarding their reciprocal interaction and the consequent impact on clinical events is still lacking.ObjectivesWe performed a metaanalysis with the aim to evaluate the prevalence of HPR in patients with and without CKD and the incidence of major adverse cardiovascular events (MACE) according to the renal and platelet function status in current literature (co‐primary endpoints). Secondary endpoints were myocardial infarction (MI), all‐cause death, and definite/probable stent thrombosis (ST).MethodsWe searched on PubMed, EMBASE, and Cochrane Library studies investigating CKD and HPR on clopidogrel in patients suffering CAD who underwent PCI and their related outcomes. Overall, 13 studies including 22.464 patients were selected. Odds ratios (ORs) and 95% confidence intervals (CI) were calculated using a random‐effects model with the Mantel‐Haenszel method.ResultsPatients with CKD presented significantly higher odds of HPR compared with those without CKD (OR 1.51 [95% CI: 1.29, 1.76]). In patients without CKD, HPR was associated with increased odds of MACE (OR 1.31 [95% CI: 1.01, 1.72]), MI (OR 1.48 [95% CI: 1.17, 1.86]) and definite/probable ST (OR 2.45 [95% CI: 1.08, 5.60]). In patients with CKD, HPR was associated with higher odds of both MACE (OR 1.61 [95% CI: 1.14, 2.27]) and MI (OR 1.69 [95% CI: 1.11, 2.59]), compared to those without HPR.ConclusionsOur analysis shows that HPR on clopidogrel is more frequent in patients with CKD treated with PCI. Patients with HPR are exposed to a high risk of MACE after PCI, regardless of the renal function status.
Diagnostic performance and prognostic impact of coronary angiography‐based Index of Microcirculatory Resistance assessment: A systematic review and meta‐analysis
Authors: Li Weijia , Takahashi Tatsunori , Rios Saul A. , Latib Azeem , Lee Joo Myung , Fearon William F. , Kobayashi Yuhei 
Published: January 2022

AbstractBackgroundThe Index of Microcirculatory Resistance (IMR), measured with a pressure‐thermistor tipped coronary guidewire has been established as a gold standard for coronary microvascular assessment. Angiography‐based IMR (angio‐IMR) is a novel method to derive IMR without intracoronary instrumentation or the need for adenosine.MethodsPubMed and Embase databases were systemically searched in November 2021 for studies that measured angio‐IMR. The primary outcomes were pooled sensitivity and specificity as well as the area under the curve (AUC) of the summary receiver operating characteristic curve using IMR as a reference standard.ResultsA total of 129 records were initially identified and 8 studies were included in the final analysis. Overall, 1653 lesions were included in this study, of which 733 were in patients presenting with ST‐segment elevation myocardial infarction. Angio‐IMR yielded high diagnostic performance predicting wire‐based IMR with pooled sensitivity = 0.81 (95% confidence interval: 0.76, 0.85), specificity = 0.80 (0.72, 0.86), and AUC = 0.86 (0.82, 0.88), which was similar irrespective of patient presentation. When the clinical outcome was compared between high versus low angio‐IMR in patients presenting with myocardial infarction, high angio‐IMR predicted an increased risk of major adverse cardiac events (MACE).ConclusionOur study found that coronary angio‐IMR has relatively high diagnostic performance as well as prognostic values predicting MACE, supporting its use in clinical practice.
Bacterial translocation as a cause of ventriculoperitoneal shunt infection: A case report
Authors: Owusu‐Adjei Brittany , Ogagan Charles , Smith Jordan , Luiselli Gabrielle , Johnson Mark D. 
Published: January 2022

AbstractBacterial translocation as a mechanism of distal catheter infection may play a larger role in ventriculoperitoneal shunt infections than previously recognized.
Cardiac and respiratory arrest in a 12‐year‐old girl with acute permethrin oral toxicity: A case report
Authors: Atashi Hesam Adin , Zaferani Arani Hamid , Agatha Felicia , Ghorani Seyyed Mojtaba , Teimouri Khorasani Mahya Sadat , Moalem Masoumeh 
Published: January 2022

AbstractPermethrin (PER) is widely employed as the most frequently used type I synthetic pyrethroid insecticide. Despite its worldwide application, reports of pediatric toxicity following permethrin administration are scarce. The present report describes the case of a 12‐year‐old girl with cardiac and respiratory arrest resulting from self‐induced oral toxicity by permethrin.
Cranial internal hemipelvectomy (iliectomy) with limb sparing for a dog with ilial chondrosarcoma: A case report
Authors: Downey Amy C. , Mathews Kyle G. , Borst Luke 
Published: January 2022

AbstractCranial internal hemipelvectomy can be successful for excision of ilial CSA with minimal complications. Iliectomy with adjuvant radiation therapy was well tolerated in a dog with grade II ilial CSA. The dog survived 1,271 days postoperatively and supposedly succumbed to a disease process unrelated to the CSA.
Older adult living independently in a public rowhouse project after the 2011 Fukushima earthquake: A case report
Authors: Ito Naomi , Kinoshita Yuri , Morita Tomohiro , Fujioka Sho , Tsubokura Masaharu 
Published: January 2022

AbstractWe study an older Japanese woman who lived independently with minimal nursing or informal support from others in the rowhouse after the 2011 Fukushima disaster. This case report supports the effectiveness of Idobata nagaya as a measure of the municipality and offers an evidence‐based approach to reconstruction after a disaster. Considering the global population aging and isolation trends, the lesson from this case may apply to other settings beyond disasters.
Blood transfusion‐induced posterior reversible encephalopathy syndrome presenting severe brain atrophy: A report of two cases
Authors: Shiraishi Wataru 
Published: January 2022

AbstractSeveral cases of posterior reversible encephalopathy syndrome (PRES) after blood transfusion have been reported, but the long‐term prognosis is unknown. Here, we report two cases of blood transfusion‐associated PRES with severe brain atrophy at 1 year after onset. We report the case with a discussion of pathological mechanisms.
Tailored Lipid Monolayers Doped with Gold Nanoclusters: Surface Studies and Electrochemistry of Hybrid‐film‐covered Electrodes
Authors: Wieckowska Agnieszka , Jablonowska Elzbieta , Dzwonek Maciej , Jaskolowski Marcin , Bilewicz Renata 
Published: January 2022

AbstractMuch attention has been given to the electrochemistry and electrochemical applications of Au nanoclusters (AuNCs) because of their unique electrochemical and optical features. However, little is known so far about their assembly with lipids or the formation of biological‐nonbiological hybrid monolayers either at the air‐water interface or on solid substrates. In this study, we synthesized AuNCs (Au25(SC4)180) with a diameter ca. 0.85±0.25 nm for the gold core, characterized the AuNCs using transmission electron microscopy (TEM) and dynamic light scattering (DLS) and, for the first time, immobilized AuNCs on the electrode in the form of an AuNC‐doped lipid monolayer. The Langmuir‐Blodgett technique at the air‐water interface allowed us to strictly control the composition of the mixed monolayer and monitor changes in the monolayer organization at the air‐water interface upon doping with AuNCs. The hybrid monolayer assembly was transferred to an indium‐tin oxide (ITO) substrate, and the electrochemical properties of the modified electrode were studied via electrochemical impedance spectroscopy (EIS) and cyclic voltammetry. With an increase in dispersion of the AuNCs in the lipid matrix, the ferrocyanide voltammetry peaks decreased as expected, thereby decreasing the actual conducting area of the electrode. However, the Au nanoclusters also acted as electron transfer mediators in electrode processes proceeding with overpotential, with improved effectiveness shown at very low AuNC concentrations in the lipid layer.
A Selective Copper Based Oxygen Reduction Catalyst for the Electrochemical Synthesis of H2O2 at Neutral pH
Authors: van Dijk Bas , Kinders Rick , Ferber Thimo H. , Hofmann Jan P. , Hetterscheid Dennis G. H. 
Published: January 2022

AbstractH2O2 is a bulk chemical used as “green” alternative in a variety of applications, but has an energy and waste intensive production method. The electrochemical O2 reduction to H2O2 is viable alternative with examples of the direct production of up to 20% H2O2 solutions. In that respect, we found that the dinuclear complex Cu2(btmpa) (6,6’‐bis[[bis(2‐pyridylmethyl)amino]methyl]‐2,2’‐bipyridine) reduces O2 to H2O2 with a selectivity up to 90 % according to single linear sweep rotating ring disk electrode measurements. Microbalance experiments showed that complex reduction leads to surface adsorption thereby increasing the catalytic current. More importantly, we kept a high Faradaic efficiency for H2O2 between 60 and 70 % over the course of 2 h of amperometry by introducing high potential intervals to strip deposited copper (depCu). This is the first example of extensive studies into the long term electrochemical O2 to H2O2 reduction by a molecular complex which allowed to retain the high intrinsic selectivity of Cu2(btmpa) towards H2O2 production leading to relevant levels of H2O2.