bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictors of smokeless tobacco use among the adult population of north-east India during 2009-2017: A decomposition analysis
Authors: Nair Saritha , Singh Lucky , Deepani Vijit , Alee Nongzaimayum Tawfeeq , Sharma Saurabh , Ovung Senthanro , Hijam Meena , Singh Sagolsem Roshan , Aheibam Sharmila , Singh Kh Jitenkumar , Haobijam Nirendra , Kaur Harpreet , Rao M. Vishnu Vardhana 
Published: October 2022

Background & objectives:
Contrary to overall declining trend in smokeless tobacco (SLT) use in India, an increase is observed in north-east (NE) India. This study examined the predictors of daily SLT use by gender and assessed the demographic and socio-economic characteristics that contribute to gender differences in SLT use in NE India.

Methods:
Data collected from 15,259 and 13,574 adults in the two rounds of Global Tobacco Adult Survey 1 and 2 for NE India during 2009-2010 and 2016-2017 were analyzed. Relative change, multivariable binary logistic regression and Blinder-Oaxaca decomposition analysis were used for analysis.

Results:
The findings suggest that among women in NE India, the daily SLT use significantly increased by 58 per cent between 2009-2010 to 2016-2017. Women residing in Nagaland, Manipur, Mizoram and Tripura were 3.5 and 2.5 times, respectively more likely to be daily SLT users compared to those in Assam. While age, education and wealth were the significant predictors of SLT use in both women and men, increased odds of SLT use were observed with women’s type of occupation and the State of residence. The majority of the gender differences in daily SLT use was explained by differences in work status (44%), age (26%), education (14%) and wealth status (9%) between men and women.

Interpretation & conclusions:
Increasing prevalence of SLT use amongst women in the NE States necessitates integration of gender-specific messages on harmful effects of SLT in the ongoing tobacco control programmes and development of culturally appropriate community-based interventions for cessation of SLT use.
Bioconjugate-loaded solid lipid nanoparticles for enhanced anticancer drug delivery to brain cancer cells: An in vitro evaluation
Authors: Jain Priyanka , Pandey Vikas , Soni Vandana 
Published: October 2022

Background & objectives:
The treatment of brain cancer is still challenging for an oncologist due to the presence of the blood-brain barrier (BBB) which inhibits the entry of more than 98 per cent of drugs used during the treatment of brain disease. The cytotoxic drugs used in chemotherapy for brain cancer treatment also affect the normal cells due to lack of targeting. Therefore, the objective of the study was to develop tween 80-coated solid lipid nanoparticles (SLNs) loaded with folic acid-doxorubicin (FAD) conjugate for site-specific drug delivery to brain cancer cells.

Methods:
The FAD conjugate was synthesized by the conjugation of folic acid with doxorubicin and characterized by Fourier transform infrared spectroscopy and proton nuclear magnetic resonance spectroscopy. SLNs loaded with FAD were prepared by the solvent injection method. The SLNs were characterized by the particle size, zeta potential, surface morphology, entrapment efficiency, etc.

Results:
The average particle size of FAD conjugate-loaded SLNs (SLN-C) was found to be 220.4±2.2 nm, with 36.2±0.6 per cent entrapment efficiency. The cytotoxicity and cellular uptake were determined on U87 MG cell lines. Half maximal inhibitory concentration value of the SLN-C was found to be 2.5 µg/ml, which confirmed the high antitumour activity against brain cancer cells.

Interpretation & conclusions:
The cell line studies confirmed the cytotoxicity and internalization of SLN-C in U87 MG brain cancer cells. The results confirmed that tween 80-coated SLNs have the potential to deliver the doxorubicin selectively in the brain cancer cells.
Glucose-6-phosphate Dehydrogenase (G6PD) A-Variant Frequency and Novel Polymorphism in Haiti
Authors: Vincent Jeanne P , Existe Alexandre V , Komaki-Yasuda Kanako , Boncy Jacques , Kano Shigeyuki 
Published: October 2022

ABSTRACT.
There are scarce data about the glucose-6-phosphate dehydrogenase (G6PD) variants in Haiti to guide public health guidelines. In this study, we investigated the prevalence of the G6PD mutations related to the A- variant. We found an allelic frequency of 35.8% for the A376G mutation and of 12.2% for the G202A mutation. We also found a novel C370T mutation concomitant with the A376G mutation in one study participant. The G680T and T968C mutations were not found. The G6PD deficient variant A202 (A376G and G202A mutations) has appreciable prevalence in Haiti (16.6%), consideration is warranted when using drugs such as primaquine, which may trigger hemolytic anemia among G6PD-deficient people.
Image Out of Place
Authors: Savchuk Valery V. 
Published: October 2022

The article deals with the search for the sources of visual pollution. While the information environment, alongside with pollution of air, water and food, has been already recognized as the new area of contamination, the pollution of visual environment has not yet been listed among the spheres monitored by the ecologists. The symptoms of visual contamination are not identified, and the sources – apart from advertising – are unknown not only to environmental activists, but also to the specialists. The main thesis of the article is as follows: the pollution of visual environment affects the health of people no less negatively than traditional sources of environmental threats. However, visual pollution is not visible; it has not yet been the subject of close study, so we do not yet have any record of its species, or the criteria for the dangerous level of pollution exceedance, nor recommendations for prevention and ways and techniques of getting rid of it. The uncertainty of the sources of visual pollution leads in the long term to disastrous health consequences, because the moral, spiritual and physical well-being of a person living in it depends on how healthy and favourable the visual environment is. Huge fields of plastic packaging and disposable dishes floating in the ocean are not only visual pollution, but also pollution of water, marine inhabitants, and soil; while in the urban environment it is difficult to separate visual dirt from pollution of air, water, land. It is concluded that the source of the pollution is a substance both out of place, without a place or outside the place. The source of pollution can be the reverse side of purity of the visual environment brought to the limit, to sterility, to geometric rigidity, which accompanies the “pathos of colonization of nature by geometry”.
From Masotopia to Thigmotaxis: the Tame of Paradoxal Spaces
Authors: Ocheretyany Konstantin A. 
Published: October 2022

Architecture is rooted in the web of metaphors by which man lives. These metaphors are rooted not so much in our thinking as in our body. However, the establishment of the monopoly of optocentrism subordinated these metaphors to the technological and clinical logic of the organization of space, sterilizing it, exploiting the geons – namely, the invariants with respect to the point of view, and forming masotopia, i.e. places that reduce person’s abilities, reduce the essence of one’s activity to nothing and, accordingly, deepen feelings of despair and guilt. The challenge is to compel a thigmotactic turn in smart city planning. Tigmotaxis in ecology is an orientation by a variety of points of contact with the environment, which allow you to resist currents, take the optimal position of the body and maintain tone. To balance the geon monopoly with thigmotaxis means to re-actualize the bodily resource: emotional, sensory, behavioral. The article shows that such a re-actualization can only be carried out by updating the metaphorical strategies embodied in the organization of space using technologies for glitch-therapy: appealing to visual and informational data, which were considered redundant or garbage (creating noise, glitch, monster). The article is intended for media philosophers, anthropologists, urbanists and digital culture theorists.
“Slow” Visual Environment in the Urban Landscapes
Authors: Nikolaeva Zhanna V. 
Published: October 2022

The article observes different aspects of the visual ecology in the urban architectural environment and a new public discussion that arose around the anti-acceleration trends (“Slow Architecture”, “Slow Cities”). The theory of the urbanized landscapes visual image’s perception analyzes, from the standpoint of rational aesthetics, critical theory of architecture, topological reflection, and the new ethics of consumption. Philosophical reflection on the phenomenon of slow perception of life, slow activity and the meaning of contemplation is of great importance for the formation of the concept of “slow visual environment”. The hypothesis of the need to limit the iconic forms’ entropy in the visual environment is verified by the examples of objects creating an aggressive landscape and visual pollution. Criteria are offered, defining the visual pollution of urban landscapes, as well as the methods for achieving visual environmental friendliness by slowing down the visual message.
Graffiti for the City or the City for Graffiti? Legitimacy of Graffiti in the Historical Center of Saint-Petersburg
Authors: Safonov Ivan E. , Shapiro Ekaterina V. , Lukina Ekaterina M. , Shchepkina Sofia A. 
Published: October 2022

In contemporary society there are two contradictory points of view concerning graffiti: it is vandalism; it is art. In the cities graffiti is treated ambiguously: negatively, quietly or with interest and approval. The reasons for this may be both in citizens’ tastes and in the characteristics of the graffiti itself. Why do citizens consider some graffiti acceptable and some not? This work deals with the research of the legitimacy of the graffiti in the historical center of Saint-Petersburg. The purpose of the research is to reveal the foundations of the legitimacy of illegal graffiti in the historical center.
The empirical basis consists of half-structured interviews analyzed with the thematic coding. The results show that a positive or negative reaction on the illegal graffiti appears during the discussion on the representational qualities, surface and content of the graffiti. The legitimate graffiti in the historical center of Saint-Petersburg has a connection with the history of the city and famous people, and it is also considered as a creative asset that transforms dilapidated surfaces. The results of the research may be used for the resolution of the conflicts between the citizens, graffiti creators and government officials providing the basis for a dialog on the common usage of the urban space. This work is also intended for the researchers of urban space, cultural city landscape and in sociology of art.
Urban Shivers: Recoding Actual Space in Disco Elysium
Authors: Medvedeva Arina R. 
Published: October 2022

The functioning of urban space in games is often passive, since the city acts as an object of observation, a scenery for the player’s actions. In the Disco Elysium game, the city receives its voice, soul, and will, which the player can observe by activating the “Shivers” skill. This study analyzes how the “Shivers” skill encodes the actual space of the city and what functions it performs for the player. We used the theoretical frame of K. Lynch and identified five patterns of encoding paths, boundaries, nodes, landmarks, and time. Each of these patterns symbolically rethinks the actual space, translating it into the virtual language of artistic techniques. The analysis revealed that the use of a unifying interface for displaying mental chains, including the “Shivers” skill, shifts the focus from interpreting the visual appearance of space to drawing an analogy between the symbolic recoding of this space and the cognitive architecture of the protagonist. Thus the analogy is transformed into a “conciliatory contrast”. There is no need for a total renewal of space while a combination of conflicting qualities preserves, maintaining the essence of each of them.
Advertising Design of Urban Development
Authors: Leonova Irina A. , Khramova Marina M. , Zaichkina Natalya V. 
Published: October 2022

Outdoor advertising has traditionally been considered one of the most important components of the mass media complex. Having an impact on all layers of society, advertising has become a kind of projection of the values that society lives by, and reflects its social and cultural level. However, the redundant use of outdoor advertising has led to the fact that in recent years the problem of the lack of aesthetics of Russian cities has become very acute. We studied and analyzed the current situation with poor-quality outdoor advertising design in modern cities to search new approaches and tools to solve the problem of unsightly cities on the example of the city of Astrakhan. The research was based on the synergetic principle of studying the object, on the method of system analysis of psychological diagnostics (observation, conversation, questionnaire), and on the analysis of the existing situation of outdoor advertising in Astrakhan. We also suggested the list of aspects and conditions important for creating interesting in design and content outdoor advertisement. Analyzing the answers to the questionnaire and basing on the study of the state of outdoor advertising in the urban environment, we formulated the conditions of normalizing the state of the urban space, meaning its quality and placement. Outdoor advertising is developing along with the improvement of information and communication technologies. A person’s contact with advertising in contemporary city is inevitable. At the same time, there are already a lot of tools available at the moment, to strengthen the impact of advertising on citizens. Therefore, it is necessary to approach the choice of a particular tool with special responsibility, so that advertising, as an integral component of an up-today city, does not damage the urban space.
Managing Risk in a Post-COVID-19 Economy: Investors’ Perception of Lagos State Real Estate Sector
Authors: Ogiri Itotenaan Henry , Nosiri Hillary , Igoni Suoye 
Published: October 2022

Purpose: As the global community continues to grapple with the effect of the COVID-19 pandemic, there is a prospect of negative/undesirable business outcomes in Nigeria. The scourge has been a regular topic of discussion in businesses, policy-making, and the academic community in many countries around the world. The pandemic has introduced a novel systematic risk class in the real estate sector. This study investigated how real estate investors in Lagos State perceive the emerging business climate following the pandemic.
Methodology: The study had a population of 2,400 while a sample size of 240 was drawn using a 10% rate. The study adopted a descriptive survey design. The statistical Package for Social Sciences (SPSS) was used to analyze data collected through questionnaires.
Findings: The findings showed that COVID-19 had a significant relationship with the level of investment in real estate in Lagos State though at a weak linear associative level. Secondly, while risk managers in these sectors have adopted different strategies to minimize their risk exposures, the study revealed that funds providers are placing a higher risk premium on investible capital as a result of uncertainties in the economic outlook occasioned by the COVID-19 pandemic. However, the study shows that the demand for real estate property in Lagos State was not negatively affected to a significant extent as a result of the pandemic, but rather a shift in preferences by property owners and occupiers. The study has implications for taxation and housing policy as well as business planning decisions.
Recommendation: The study recommends that government should create a favorable investment climate for real estate investors with appropriate risk mitigation measures that can reactivate the real estate sector while aiding its recovery from the COVID-19 debilitations.
Gobierno digital y su relación con desempeño docente en Covid-19. Unidad de posgrado de ing. de Sistemas e Informática
Authors: Espejo Briceño Hugo José Luis , León Fernández Cayo Víctor , Alberca Márquez Rocío Regina , Fabián Germán Cristian Manuel 
Published: October 2022

Esta investigación tiene como objetivo principal “establecer cómo se relaciona el gobierno digital con el desempeño docente en la Unidad de Posgrado de Ingeniería de Sistemas e Informática de la Universidad Nacional Mayor de San Marcos”. Relacionando las dimensiones “Enfoque estratégico digital”, “Infraestructura tecnológica”, Objetivos de “Gobierno Digital” y “Capacitación de Gobierno Digital”, por el lado de Gobierno Digital vs. Desempeño tecnológico, Desempeño disciplinar, Desempeño Pedagógico por parte del Desempeño Docente. “La hipótesis es que el Gobierno Digital se relaciona positivamente con el Desempeño Docente en la Unidad de Posgrado en Ingeniería de Sistemas e Informática de la Universidad Nacional Mayor de San Marcos, 2020”. El enfoque del estudio es cuantitativo, así mismo, su alcance es descriptivo con un diseño no experimental correlacional. “La muestra está conformada por 20 docentes de la Unidad de Posgrado de Ingeniería de Sistemas e Informática de la Universidad Nacional Mayor de San Marcos”. Los resultados de la investigación sugieren que existe una relación fuerte entre «Gobierno Digital» y «Desempeño Docente», siendo el coeficiente de correlación de Spearman de .776 lo cual indica una alta correlación.
Uso de las TIC en la motivación para el aprendizaje de estudiantes universitarios de la Facultad de Ingeniería Electrónica y Eléctrica de la UNMSM – 2021
Authors: Ponce Martínez Luis Mark Rudy 
Published: October 2022

La investigación científica que se ha realizado es de tipo básica, la cual tuvo como objetivo determinar si el uso de los recursos tecnológicos influye en la motivación para el aprendizaje de estudiantes universitarios de la Facultad de Ingeniería Electrónica y eléctrica de la UNMSM -2021.
El diseño de la investigación fue experimental. Para la recolección de datos, se elaboró cuestionarios estructurados para medir la variable motivación para el aprendizaje, los cuales fueron aplicados a una muestra conformada por 35 estudiantes de grupo control y 35 estudiantes del grupo experimental.
Los resultados obtenidos permiten evidenciar que El uso de los recursos tecnológicos influye en la motivación para el aprendizaje de estudiantes universitarios de la Facultad de Ingeniería Electrónica y eléctrica de la UNMSM -2021, al obtenerse que el valor de p = 0,000 el cual fue menor a 0,05, en cuanto al postest, después de la aplicación del uso de las tecnologías de la información y comunicación a los estudiantes en el desarrollo del programa implementado, mostrándose como se evidencia en los resultado que en el postest del grupo experimental el 100% de los estudiantes llegaron a un nivel alto.
Moderating Effect of Ownership Structure on the Relationship between Working Capital Management Decisions and Financial Performance of Tea Firms in Kenya
Authors: Yegon Charles Kiprotich , Muturi Willy , Oluoch Oluoch 
Published: October 2022

Purpose: The general objective of this research study was to examine the moderating effect of ownership structure on the relationship between working capital management decisions and financial performance of tea firms in Kenya. Expansive research studies are available on the strategies employed by tea firms to boost their financial performances. However, Very minimal of these research studies are geared towards the contribution of working capital management decisions employed by these companies within the tea sector in Kenya.
Methodology: The study employed a correlational research design. The data was collected was collected from the audited financial statements of all the multinationals and KTDA managed tea firms in Kericho, Bomet and Nandi counties of Kenya. The data was analyzed by employing both descriptive and inferential statistics.
Findings: This research study revealed that there exists a moderating effect of ownership structure on the relationship between working capital management decisions and financial performance of tea firms in Kenya.
Unique contribution to theory, practice and policy: The research study recommended that the KTDA managed tea firms should be advised to adopt the strategies employed by multinational tea firms in order to boost and improve their financial performance. Tea firms are strongly cautioned against increasing accounts receivables period, accounts payables payment period and inventory conversion period because this would minimize their financial performance in the long-run.
Optical and Photovoltaic Properties of New Synthesized Quinoxaline-2,3 Dione Derivatives for Efficient Dye Sensitized Solar Cell Application
Authors: El Assyry Abdeslam , Rafiq Issam , Rbaa Mohamed , Derouiche Abdelali , Lakhrissi Brahim 
Published: October 2022

In this study, the synthesis of 4 new heterocyclic compounds derived from quinoxalinedione were presented, which have been characterized by 1H and 13C NMR spectroscopy. The solar cells’ photovoltaic properties based on these novels organic compounds donor-π-acceptor dyes were studied. Density functional theory DFT method is realized to optimize electronic parameters, optical and photovoltaic properties for some new 8-hydroxyquinoline derivatives based on quinoxaline-2,3-dione. The results have shown that time-dependent DFT (TDDFT) investigations with polarizable continuum model PCM were significantly able to foretell the excitation energy and the spectroscopy of the molecule. The highest occupied molecular orbital HOMO and the lowest unoccupied molecular orbital LUMO energy levels of these molecules can ensure a positive impact on the dye regeneration and electron injection process. Injection driving force ΔGinject, light-harvesting efficiency LHE, reorganization energy λtotal and open-circuit photovoltage Voc provide qualitative predictions on these dyes’ reactivity. Among these 4 molecules, the compounds which can be used as organic solar cells have determined.
HIGHLIGHTS

We presented the synthesis and the characterization of a new series of heterocyclic compounds obtained by association of 8-hydroxyquinoline with quinoxalindione derivatives.
The synthesis of this series of compounds was carried out by simple conditions but with good yields and the characterization data shows that there is good consistency between the spectroscopic data and the proposed structures
These new compounds were obtained according to simple procedures with good yields and they have been the subject of a theoretical study
This investigated process can be employed to predict the optical and photovoltaics properties on the other compounds and polymers, and it encourages to synthesis the novel organic solar cell materials

GRAPHICAL ABSTRACT