bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using the Consolidated Framework for Implementation Research to Foster the Adoption of a New Dementia Education Game During the COVID-19 Pandemic
Authors: Hung Lillian , Mann Jim , Upreti Mona 
Published: August 2022

AbstractBackground and ObjectivesThe pandemic of coronavirus disease 2019 challenged educators to move staff education online and explore innovative ways to motivate learning to support dementia care for patients in geriatric settings. This article presents how the Consolidated Framework for Implementation Research (CFIR) was used to support the adoption of an online dementia education game in Canadian hospitals and long-term care homes (LTC). The dementia education was codeveloped with local staff and patient partners to teach practical person-centered care communication techniques.Research Design and MethodsCFIR guided our strategy development for overcoming barriers to implementation. Research meetings were conducted with practice leaders, frontline health care workers, and a patient partner. Our analysis examined 4 interactive domains: intervention, inner context, outer settings, and individuals involved and implementation process.ResultsOur analysis identified 5 effective strategies: Easy access, Give extrinsic and intrinsic rewards, Apply implementation science theory, Multiple tools, and Engagement of champion. The CFIR provided a systematic process, a comprehensive understanding of barriers, and possible enabling strategies to implement gamified dementia education. Interdisciplinary staff (n = 3,025) in 10 hospitals and 10 LTC played online games. The evaluation showed positive outcomes in knowledge improvement in person-centered dementia care.Discussion and ImplicationsGamified education in dementia care offers a social experience and a component of fun to promote adoption. In addition, CFIR is useful for engaging stakeholders to conduct project planning and team reflection for implementation. The real-time discussion and adjustment helped overcome challenges and timely meet the needs of multiple organizations.
Analysis of CF patient survival confirms STAT3 as a CF-modifying gene with changing impact over time
Authors: Dunsche Inga , Raddatz Ellen L , Ismer Haide , Hedtfeld Silke , Tamm Stephanie , Moser Saskia , Kontsendorn Julia , Tümmler Burkhard , Janciauskiene Sabina , Dittrich Anna-Maria , Stanke Frauke 
Published: August 2022

Abstract

Introduction and aim
The signal transducer and activator of transcription 3 (STAT3) has been identified as one of the cystic fibrosis (CF) modifying genes. In this study, we aimed to assess the association between STAT3 genotype and CF patient survival over several decades and to investigate the effect of STAT3 inhibition on epithelial CFTR expression.

Methods
We analyzed the informative genetic marker STAT3Sat for its association with survival in 174 p.Phe508del-CFTR homozygous CF patients treated at the CF center in Hannover spanning birth cohorts from &gt;3 decades (1959–1994). Furthermore, we treated two epithelial cell lines with STAT3 inhibitors and monitored changes of CFTR protein expression by western blot.

Results
Only for p.Phe508del-CFTR homozygous patients born prior to 1975, survival was significantly influenced by STAT3sat genotype (P = 0.023). The expression levels of STAT3 and CFTR positively correlated in epithelial cell lines (P = 0.01).

Conclusions
Our results in different birth cohorts identified a time-dependent impact of STAT3 genotype on CF patients’ survival and found that improved symptomatic treatment of later-born CF patients obviates STAT3’s modifying influence. Consistent with our previous results, STAT3-specific inhibition resulted in increased CFTR expression in the epithelial cell line 16HBE14o-. Thus, care should be taken when CF-modifying genes are studied in cross-sectional cohorts as the impact of modifying genes might not be invariant in the light of changing therapeutic regimens.
On the Composition of Two Spherical Twists
Authors: Barbacovi Federico 
Published: August 2022

Abstract
Segal [17] proved that any autoequivalence of an enhanced triangulated category can be realised as a spherical twist. However, when exhibiting an autoequivalence as a spherical twist one has various choices for the source category of the spherical functor. We describe a construction that realises the composition of two spherical twists as the twist around a single spherical functor whose source category semi-orthogonally decomposes into the source categories for the spherical functors we started with. We give a description of the cotwist for this spherical functor and prove, in the special case when our starting twists are around spherical objects, that the cotwist is the Serre functor (up to a shift). We finish with an explicit treatment for the case of $\mathbb {P}$-objects.
A Shadow Perspective on Equivariant Hochschild Homologies
Authors: Adamyk Katharine , Gerhardt Teena , Hess Kathryn , Klang Inbar , Kong Hana Jia 
Published: August 2022

Abstract
Shadows for bicategories, defined by Ponto, provide a useful framework that generalizes classical and topological Hochschild homology. In this paper, we define Hochschild-type invariants for monoids in a symmetric monoidal, simplicial model category $\mathsf V$, as well as for small $\mathsf V$-categories. We show that each of these constructions extends to a shadow on an appropriate bicategory, which implies in particular that they are Morita invariant. We also define a generalized theory of Hochschild homology twisted by an automorphism and show that it is Morita invariant. Hochschild homology of Green functors and $C_n$-twisted topological Hochschild homology fit into this framework, which allows us to conclude that these theories are Morita invariant. We also study linearization maps relating the topological and algebraic theories, proving that the linearization map for topological Hochschild homology arises as a lax shadow functor, and constructing a new linearization map relating topological restriction homology and algebraic restriction homology. Finally, we construct a twisted Dennis trace map from the fixed points of equivariant algebraic $K$-theory to twisted topological Hochschild homology.
Object classification on video data of meteors and meteor-like phenomena: algorithm and data
Authors: Sennlaub Rabea , Hofmann Martin , Hankey Mike , Ennes Mario , Müller Thomas , Kroll Peter , Mäder Patrick 
Published: August 2022

ABSTRACT
Every moment, countless meteoroids enter our atmosphere unseen. The detection and measurement of meteors offer the unique opportunity to gain insights into the composition of our solar systems’ celestial bodies. Researchers therefore carry out a wide-area-sky-monitoring to secure 360-degree video material, saving every single entry of a meteor. Existing machine intelligence cannot accurately recognize events of meteors intersecting the earth’s atmosphere due to a lack of high-quality training data publicly available. This work presents four reusable open source solutions for researchers trained on data we collected due to the lack of available labelled high-quality training data. We refer to the proposed data set as the NightSkyUCP data set, consisting of a balanced set of 10 000 meteor- and 10 000 non-meteor-events. Our solutions apply various machine-learning techniques, namely classification, feature learning, anomaly detection, and extrapolation. For the classification task, a mean accuracy of 99.1 per cent is achieved. The code and data are made public at figshare with DOI 10.6084/m9.figshare.16451625.
SDSS IV MaNGA - star-formation driven biconical outflows in face-on galaxies
Authors: Bizyaev D , Chen Yan-Mei , Shi Yong , Roy Namrata , Riffel Rogerio , Riffel Rogemar A , Fernández-Trincado José G 
Published: August 2022

ABSTRACT
We find 132 face-on and low inclination galaxies with central star formation driven biconical gas outflows (FSFB) in the SDSS MaNGA (Mapping Nearby Galaxies at APO) survey. The FSFB galaxies show either double peaked or broadened emission line profiles at their centres. The peak and maximum outflow velocities are 58 and 212 km s−1, respectively. The gas velocity dispersion reveals a mild dependence on the central star formation surface density compatible with models of gas dispersion powered by the Jeans instability in gas clumps or by gas turbulence dissipation. We estimate the gas outflow rate and conclude that the central gas depletion time does not depend on galactic mass. In turn, the ratio of the gas outflow rate to the gas consumption rate by the star formation is low in massive galaxies and high in low mass objects, while the star formation is a more rapid process of the gas consumption. We compare properties of the FSFB galaxies with a control sample of 375 comparison galaxies and find that the FSFB objects have high central concentration of star formation and also younger central stellar population with respect to their periphery. We analysed the environment of the galaxies and identified nearby satellites and elements of low surface brightness structure. We see that many tidal-enhanced features that can be assigned to early and intermediate stages of galactic interaction are much more frequent in the FSFB galaxies with respect to the comparison sample. We conclude that the gas should be replenished via the accretion from small satellites.
The androgen receptor couples promoter recruitment of RNA processing factors to regulation of alternative polyadenylation at the 3' end of transcripts
Authors: Caggiano Cinzia , Pieraccioli Marco , Pitolli Consuelo , Babini Gabriele , Zheng Dinghai , Tian Bin , Bielli Pamela , Sette Claudio 
Published: August 2022

Abstract
Prostate cancer (PC) relies on androgen receptor (AR) signaling. While hormonal therapy (HT) is efficacious, most patients evolve to an incurable castration-resistant stage (CRPC). To date, most proposed mechanisms of acquired resistance to HT have focused on AR transcriptional activity. Herein, we uncover a new role for the AR in alternative cleavage and polyadenylation (APA). Inhibition of the AR by Enzalutamide globally regulates APA in PC cells, with specific enrichment in genes related to transcription and DNA topology, suggesting their involvement in transcriptome reprogramming. AR inhibition selects promoter-distal polyadenylation sites (pAs) enriched in cis-elements recognized by the cleavage and polyadenylation specificity factor (CPSF) complex. Conversely, promoter-proximal intronic pAs relying on the cleavage stimulation factor (CSTF) complex are repressed. Mechanistically, Enzalutamide induces rearrangement of APA subcomplexes and impairs the interaction between CPSF and CSTF. AR inhibition also induces co-transcriptional CPSF recruitment to gene promoters, predisposing the selection of pAs depending on this complex. Importantly, the scaffold CPSF160 protein is up-regulated in CRPC cells and its depletion represses HT-induced APA patterns. These findings uncover an unexpected role for the AR in APA regulation and suggest that APA-mediated transcriptome reprogramming represents an adaptive response of PC cells to HT.
(Dis)taste of Race
Authors: Stoler Ann Laura 
Published: August 2022

AbstractThis chapter analyzes the phrase “Taste is a social relationship made flesh,” which were the final words of the postscript of Pierre Bourdieu’s five-hundred-page monumental study, Distinction: A Social Critique of the Judgment of Taste. It describes the “flesh” as a figure in the treatment of the judgments of high and low culture, the criteria of consumption, and the rankings of approval and disdain. It also points out how the flesh’s portals, hues, porosities, and receptors are alive to the demands of taste. The chapter cites Bourdieu’s words that taste is a social relationship that is embodied and has literally become second nature. It considers “made flesh” as a symptom of difference between languages or locating a word situated within the measurable differences among languages.
Colonial Diffractions in (Il)liberal Times
Authors: Stoler Ann Laura 
Published: August 2022

AbstractThis chapter introduces popular mobilizations and occupations of public space that come up against right-wing retrenchment and xenophobias. It mentions calls for the restitution of colonially procured and stolen objects to join managerial performances of colonial apology by European and North American heads of state. It also highlights burgeoning initiatives and mandates to decolonize classrooms, public institutions, disciplines, speech, and behavior that exceed confines of academic worlds. The chapter pursues an unwieldy set of propositions, identifying two radical shifts in how colonialism is politically positioned and temporally framed. It reviews colonial invocations that cover ground than ever before as the archive stretches across the academe, public education, indigenous communities, activist blogs, and the mainstream press.
Forms
Authors: Spelke Elizabeth S. 
Published: August 2022

Abstract
Until recent times, human survival depended on our ability to identify and categorize the living kinds that provided our food and shelter, as well as those who threatened us with poisoning or predation. Most children who are alive today, in contrast, get their food from packages in stores and kitchens, and most research on infants’ knowledge of object kinds focuses on their learning about artifacts. Here the author focuses on research probing the shape properties by which infants categorize objects and learn their functions. She suggests that infants are endowed with core knowledge of the abstract forms and functions shared by all living kinds. Equipped with this knowledge, infants are prepared to learn about the forms and functions of the particular living kinds that surround them, through cautious exploration and observation of other people’s actions. These learning processes also allow infants living in industrialized cultures to begin learning about the forms and functions of factory-produced artifacts, but core knowledge captures these objects poorly. Learning about artifacts begins to accelerate later in childhood.
Origins
Authors: Yaden David B. , Newberg Andrew B. 
Published: August 2022

Abstract
Where do spiritual experiences come from? There is, of course, a theological/philosophical level as well as a more practical level to this question. But as shown time and again in the preceding chapters of this book, the Jamesian approach of setting aside theological questions can be taken so as to instead focus on scientifically tractable subjects, such as the conditions that seem to make these experiences occur. This chapter describes how scientific research has established a number of circumstances, dispositions, mindsets, rituals, practices, psychoactive substances (such as psychedelics), and, perhaps in the near future, other neurotechnologies that make spiritual experiences more likely to occur.
Types of Spiritual Experience
Authors: Yaden David B. , Newberg Andrew B. 
Published: August 2022

Abstract
There are different types of spiritual experience. This chapter provides a data-driven typology of spiritual experience. This typology of spiritual experiences organizes the chapters in Part II of the book. The goal of this part of the book is to provide a kind of scientific guide to the varieties of spiritual experience using a 21st-century scientific approach. This approach, using statistical tools not available to James, allows for a better understanding of the varieties of spiritual experiences. In each particular type of experience, as well as with spiritual experience in general, there are relatively reliable clusters of subjective qualities. The belief is presented that this data-driven factor analysis of types will help to drive some progress in the scientific study of spiritual experience.
Mystical Experiences
Authors: Yaden David B. , Newberg Andrew B. 
Published: August 2022

Abstract
Mystical experiences are among the most well-studied spiritual experience. This chapter defines mystical experience as inner experiences involving an intensely felt fading of the sense of self and/or feelings of increased connectedness, up to and including the sense of complete unity. These kinds of feelings go well beyond our normal day to day sense of self-awareness. In ordinary consciousness, there is generally the impression that there is a me on the one hand and then, on the other hand, everything else. Under some circumstances, however, this sense of self can be inverted––during such moments, one’s sense of self can fade into the background and become a part of, rather than apart from, everything else. Neuroimaging of meditators and nuns has shown that brain regions that differentiate one’s self from the rest of the world are inhibited during these kinds of experiences.
The Middle East after the Fall of Ur
Authors: Wagensonner Klaus 
Published: August 2022

AbstractThe weak reign of the last king of Ur, Ibbi-Sin, left space and opportunity for local rulers to establish their own dynasties in Mesopotamia at the end of the third millennium bc. In Isin, Išbi-Erra, one of Ibbi-Sin’s generals, rose to power, and he and his successors saw themselves as the legitimate heirs of the kings of Ur. Sumerian remains the language of the administration and economy and is also employed for most of the royal inscriptions and the extant literature, which is highly reminiscent of court poetry composed for the kings of Ur. The peace and prosperity achieved under the early Isin kings was short-lived, as soon another player joined the political game: the kings of Larsa, who traced back their origins to earlier ancestors than those of Isin. The rulers of the two rival kingdoms took advantage of any weakness in their opponents, and in the first two centuries of the second millennium bc, the size of their territories and their rule over the Mesopotamian cities were in constant flux. The peak of Larsa’s rule is reached with a new dynasty established by Kudur-mabuk, who installed his two sons successively onto the throne of Larsa. The last king of Larsa, Rim-Sin, eventually conquered Isin, and the kingdom of Larsa thus reached its largest extent. Judging from the year names of the second half of his reign, Rim-Sin appears to have rested on his laurels, as no further military activities are recorded. He ended his reign as the prisoner of Hammurabi of Babylon, who conquered Larsa and integrated all its territories into his realm.
Peer Groups and (In)equality
Authors: Sabbagh Clara 
Published: August 2022

Abstract
Chapter 11 investigates how children’s and young people’s peer groups can promote either equality or inequality through everyday interaction. Using ethnographic evidence to illustrate these processes, the chapter focuses on the furthering of distributive justice norms in various cultural settings. These norms underlie two primary forms of social exchange: balanced and generalized reciprocity. Moreover, the chapter operates with Opotow’s notion of the scope of justice, which refers to the applicability of justice to individual groups. This framework is applied to examine the ways through which children and young people negotiate their group boundaries in everyday life, creating moral inclusion and exclusion in a given community. These processes either enhance or discard as irrelevant ethnic, racial, and gender inequalities that characterize the wider society. Hence, peer group interaction does not necessarily imply equal relationships but rather the reproduction of existing social inequalities.
Moratorium and Political Justice
Authors: Sabbagh Clara 
Published: August 2022

Abstract
Chapter 12 focuses on common non-formal educational practices and elaborates how they embody and instill contested views of citizenship and political justice. The issue of what constitutes a just distribution of power or the ability to influence is highly contested in democratic societies. The chapter discusses different political justice values underlying the operation of youth councils, community service, and youth activism. Youth councils embed a rights-based notion of political justice, through which children and young people learn about aspects of procedural justice, such as the right to have a voice and actively participate in decision-making. However, in youth councils, opportunities for experimentation are limited due to adults’ control. In contrast, community service instills a duty-based perspective on political justice, stressing active contribution to enhancing community or national welfare. Finally, youth activism furthers political justice as praxis, whereby justice is not just learned, but its meanings are (re)interpreted, (re)created, and enacted.
The Ballad and the Sea
Authors: Daub Adrian 
Published: August 2022

Abstract
This chapter traces the relationship of the German ballad to the sea. In the early nineteenth century, Germany’s coast was understood as ultimately exotic and regionally specific. By the late nineteenth century, through an upsurge in tourism, through cultural reinterpretation, but also due to the excitement the Kaiserreich managed to generate for the German fleet, the seashore had become nationalized. During the same period, the ballad was increasingly positioned (among its popularizers as much as among the poets themselves) as a national form, and poets from Detlev Liliencrohn to Arno Holz used the form to reconcile what was regional and what was national in life on the shore, and by extension in the ballad. This chapter focuses on how issues of language, dialect, memory, and politics became entangled as writers, both in “high” German and in regional dialects, were forced to grapple with the reality that the nation to which the ballad was thought to belong suddenly was an actual country.
Only Natural
Authors: Antony Louise 
Published: August 2022

Abstract
This volume brings together sixteen essays by Louise Antony that reflect her distinctive approach to issues at the intersections of feminist theory, epistemology, philosophy of mind, and philosophy of language. Antony proceeds from the Quinean precept that we treat knowledge as a natural phenomenon. This approach offers feminists and other progressive theorists vital tools with which to expose and dismantle ideological conceptions of knowledge, human nature, and objectivity. Naturalism’s focus on the actual (as opposed to hypothetical) circumstances under which human beings acquire knowledge illuminates and responds to feminist calls for a “situated” account of human knowledge. At the same time, Antony defends a number of views that have been the object of feminist criticism: psychological individualism, cognitive nativism, and the autonomy of semantics. These views are in no way incompatible with feminist commitments, which is good, because they enjoy broad empirical support. This volume also addresses a number of practical issues of concern to feminists: Does pornography silence women? Are we ethically entitled to moral partiality? Is legitimate authority possible? Why are there so few women in philosophy? Finally, Antony argues that genders are socially constructed and multiply realized categories that bring into concordance sets of properties that have no natural or rational connection to each other. Genders must not be identified with the categories “female” and “male,” but human sexual difference is the material, explanatory basis of gender systems: But for the existence of differences in reproductive role between females and males, gender regimes would not exist.