bluuebunny/crossref_metadata_2025_split huggingface dataset:
A atuação da Farmácia Universitária da Universidade Federal Fluminense (UFF) durante a pandemia de Covid-19
Authors: Araújo Emeli Moura de , Seba Karine Souza , Cabral Priscila Ramos , Piccoli Nilo Jorge , Mourão Samanta Cardozo , Castillo Selma Rodrigues de 
Published: February 2022

A pandemia de Covid-19, iniciada em março de 2020, desencadeou esforços dos setores públicos em diversas frentes no Brasil. Niterói, desde o início, propôs medidas de combate à doença, tais como o isolamento social, com o fechamento de escolas, praias e parques, e a obrigatoriedade do uso de máscaras, já em abril de 2020, além de ações em relação à economia, distribuição de kits de higiene e máscaras e inauguração de um hospital exclusivo. O município também celebrou parcerias com a Fiocruz, Universidade Federal Fluminense (UFF) e Universidade Federal do Rio de Janeiro (UFRJ), para o estabelecimento de protocolos, programas de testagem e, mais recente, nos programas de vacinação e reabertura gradual. Embora não tenha um vínculo formal com a rede pública de saúde do município de Niterói, a Farmácia Universitária da Universidade Federal Fluminense (FAU) funciona de forma complementar ao sistema, atendendo, em sua maioria, pacientes oriundos do Sistema Único de Saúde (SUS), incluindo os do Hospital Universitário Antônio Pedro. O objetivo do presente relato é reportar a atuação e as ações da FAU durante a emergência de saúde pública. Entre abril de 2020 e setembro de 2021, a demanda por serviços na FAU reduziu 64% e o número de formulações manipuladas e vendidas, 53%. A queda ocorreu mesmo após a reabertura de estabelecimentos e retorno às atividades. Em março de 2020, a FAU iniciou a produção de álcool 70% INPM para distribuição interna aos setores da UFF, destacando-se o Hospital Universitário Antônio Pedro, e para a Faculdade de Engenharia, com a finalidade de higienização das máscaras Face shields produzidas na unidade. Também foram produzidos mais de 100 quilos de álcool em gel 70% INPM, disponibilizados aos clientes da FAU. Estes itens, considerados essenciais na prevenção e proteção da saúde individual e coletiva, estavam esgotados no mercado no início da pandemia.
Programa Medicamento na Hora Certa: Uma estratégia para dispensação em tempos de pandemia
Authors: Takayasu Scheila Maria Graczyk 
Published: February 2022

A pandemia do novo coronavírus trouxe grandes desafios ao setor de saúde. E com a Assistência Farmacêutica não foi diferente. Para a melhoria dos fluxos e agilidade na dispensação de medicamentos, a Secretaria de Saúde de São José dos Pinhais propôs um fluxo alternativo para acesso aos medicamentos, implementando, de forma inovadora, o Programa Medicamento na Hora Certa. O objetivo foi atuar numa estratégia de dispensação de medicamentos que contemplasse o atendimento farmacêutico em todas as fases da dispensação, porém com o menor contato físico possível, a fim de evitar a propagação do coronavírus dentro do estabelecimento de saúde. O Programa consiste em utilizar-se de ferramentas de tecnologia e de comunicação para agilizar o atendimento nas farmácias. Por meio de um número de WhatsApp, o usuário encaminha previamente sua prescrição e documentos pessoais e uma equipe de técnicos as recebe e analisa técnica e legalmente, agendando o horário de retirada na Farmácia de acesso mais fácil ao usuário. Na hora e local especificados, o usuário se dirige à farmácia para receber seu medicamento previamente separado e embalado pela equipe da farmácia, sem a necessidade de retirar senha ou esperar em filas. O Programa trouxe bons resultados, e em cinco meses foram agendadas 3.626 retiradas. Também se tornou um canal de comunicação para dúvidas sobre fluxos de medicamentos. Neste período foram registradas 7.078 conversas, sendo que 51,7% destas foram finalizadas após resolução de dúvidas. Com a implantação do Programa houve diminuição do tempo de permanência do usuário nas Unidades, além de evitar o deslocamento desnecessário dos usuários que necessitavam de adequação de receitas ou sanar dúvidas referentes aos medicamentos, atingindo, desta forma, seu objetivo de agilizar a dispensação de medicamentos sem a perda da qualidade no atendimento farmacêutico.
Methods of chemical analysis applied to the wood fire investigation: a review
Authors: Paál Michal , Ház Aleš , Sochr Jozef , Labuda Ján 
Published: February 2022

Abstract
Wood fire residues can be found in various stages from less damaged material, pyrolysis products (a char) to deeply damaged material (ash). Moreover, wood burning can be influenced by fire accelerators and/or flame retardants. This paper provides a brief description and evaluation of conventional and comprehensive variants of analytical techniques with examples of their various applications at analyses of wood materials and wood fire residues. They include specificities of sampling, elemental chemical analysis, thermal analysis, extraction of compounds from fire debris, chromatographic methods and mass spectrometry, spectroscopic methods, chemometrics and quality assurance.
The effect of Salvia officinalis on blood glycemic indexes and blood lipid profile in diabetic patients: a systematic review and meta-analysis
Authors: Abdollahi Ali , Adelibahram Faeze , Ghassab-Abdollahi Nafiseh , Araj-khodaei Mostafa , Parsian Zahra , Mirghafourvand Mojgan 
Published: February 2022

Abstract
Diabetes is one of the most common endocrine disorders that increases the economic burden on the public health system. In this regard, understanding the effect of available herbs on diabetes can be useful. This systematic review was performed to determine the effect of Salvia officinalis on blood glycemic indexes and blood lipid profile (primary outcomes) and 2 h postprandial blood glucose (2HPPG), alanine transaminase (ALT) (U/L) and aspartate transaminase (AST) (U/L) and its side effects (secondary outcomes) in diabetic patients. A systematic search was conducted in the English (Cochrane Library, Medline (PubMed), Scopus, CINAHL, ProQuest and Persian databases since inception to March 2021, without publication time restriction. Two authors separately evaluated the quality of the articles using Cochrane Collaboration’s tool for assessing the risk of bias in randomized trials and extracted the data. Heterogeneity of data was evaluated by squared I (I
2). Three studies included in the review and all of them included in meta-analysis. The results of meta-analysis showed that S. officinalis reduced fasting blood sugar (FBS) (mg/dL) (MD: −31.15; 95% CI: −37.56 to −24.73; p<0.00001). It also reduced HbA1c (%) (MD: −0.94; 95% CI: −1.25 to −0.63; p<0.00001) and total cholesterol (mg/dL) (MD: −43.64; 95% CI: −83.26 to −4.02; p=0.03) and reduction of low-density protein (LDL) (mg/dL) (MD: −19.23; 95% CI: −35.81 to −2.65; p=0.02) but it did not have a significant effect on triglyceride (mg/dL) (p=0.09), and high-density lipoprotein (HDL) (mg/dL) (p=0.18). Regarding the secondary outcomes, S. officinalis also had significant effect on 2HPPG, but it did not have a significant effect on ALT (U/L) and AST (U/L). No specific side effects for this plant were reported in these three studies. The results showed that S. officinalis has a positive effect on blood glycemic status and blood lipid profile in diabetes except for triglyceride and HDL. However, due to the small number of included articles, it is recommended that stronger clinical trials be conducted in this field.
Diagnostic value of plasma lysosphingolipids levels in a Niemann–Pick disease type C patient with transient neonatal cholestasis
Authors: Bulut Fatma Derya , Bozbulut Neslihan Ekşi , Özalp Özge , Dalgiç Buket , Mungan Neslihan Önenli , Koç Uçar Habibe , Biberoğlu Gürsel 
Published: February 2022

Abstract

Objectives
Niemann–Pick disease type C (NPC) is a lysosomal storage disease due to impaired intracellular lipid trafficking caused by biallelic pathogenic variants in NPC1 or NPC2 genes. NPC is classified according to the age of onset of neurological manifestations. Cholestatic liver disease can be transient or lead to liver failure. Accompanying neurological findings can be observed at any age. In this report, an infant with a homozygous pathogenic variant in NPC1 gene whose diagnosis was eventually confirmed by specific biomarkers is described.

Case presentation
A sixteen-day-old male was admitted to hospital with prolonged jaundice. He had mild hepatosplenomegaly, conjugated hyperbilirubinemia, elevated liver transaminases, and mild hypoalbuminemia. Cholestasis resolved spontaneously and patient was readmitted due to progressive hepatosplenomegaly without any neurologic findings when he was 8 months old. Molecular investigations detected homozygous c.1123A > C (p.Thr375Pro) pathogenic variant in NPC1 gene. NPC-specific lysosomal biomarkers such as Lysosphingomyelin and Lysosphingomyelin-509 were elevated, confirming the diagnosis.

Conclusions
The clinical features of NPC are highly heterogeneous, from disease severity or age of onset to disease progression. Patients presenting with transient neonatal cholestasis and should be regularly followed for neurodevelopmental status and visceromegaly. In the case of variants of unknown significance in NPC1 gene, lysosomal biomarkers play an important role when genetic analyses are inconclusive.
Chancy Causation in Tort Law
Authors: Lahav Alexandra D. 
Published: February 2022

Abstract
Chancy causation is where the cause of an event can only be attributed probabilistically. Contrary to the understanding popular in legal theory, scientific fact plays only a minimal role in chancy causation cases. As a matter of metaphysics, factual inquiry can only determine whether an event has a tendency to cause an outcome. Yet tort doctrine requires that the plaintiff prove a counterfactual: that but for the event, the outcome would not have occurred. Understanding that in chancy causation cases proving the counterfactual is impossible is the first step towards a discussion of what really ought to matter in chancy causation cases: whether imposing liability is normatively desirable. Methodologically, the Essay builds on scholarship about the metaphysics of causation as a first step to understanding this legal concept. If it is true that causation cannot be pinned down deterministically, as chancy causation cannot, then what determines factual causation? The answer is policy. I call this approach “pragmatic” because it evaluates the use of an idea rather than claims regarding its metaphysical truth. But there is a metaphysical piece here as well. We only get to the point of applying a pragmatic analysis by understanding something about the metaphysics of causation.
Transition us together: development of a parent-centered toolkit to support adolescents with rheumatic disease transition to adult care
Authors: Dushnicky Molly J. , Scott Jessica , McCauley Dayle , Gorter Jan Willem , Beattie Karen A. , Batthish Michelle 
Published: February 2022

Abstract

Objectives
While the transition period can be a difficult time for adolescents with chronic health conditions, parents also face challenges in understanding their changing role and how to support their children. To date, minimal interventions have focused on supporting and empowering parents during this period.

Methods
We co-created a toolkit with and for parents to help prepare them for their child’s transition to adult care. The toolkit was created using an iterative process of reviewing existing resources with integrating feedback from rheumatology patients and parents. Input was sought from the Family and Youth Advisory Councils at McMaster Children’s Hospital in Hamilton, Canada.

Results
The two components of the toolkit include a Transition Road Map and a Parent Guide to Transition. Five domains of transition readiness were established as pillars of the Road Map. Within each domain, a checklist to achieve self-management was established. The Parent Guide was developed to highlight important information including defining transition, outlining differences between pediatric and adult care, and providing tips on helping and supporting adolescents.

Conclusions
A Parent Toolkit directed at the Transition from Pediatric to Adult Rheumatology Care was developed and underwent extensive review with multiple stakeholders. Ongoing research on its impact on transition readiness is underway.
Electrically tunable metasurface by using InAs in a metal–insulator–metal configuration
Authors: Park Junghyun , Kim Seong Jun , Sorger Volker J. , Kim Soo Jin 
Published: February 2022

Abstract
The ability of modulating optical properties at a lateral subwavelength scale is of crucial importance due to its potential applications for wide-angle holographic displays, optical communications, and interferometric sensors. Here, we present an electrically tunable metasurface whose optical properties can be element-wise controlled at the lateral subwavelength scale in the mid-infrared wavelength regime. Our proposed device facilitates an n-doped InAs layer as a dynamic-tunable layer, and the charge carrier concentration inside the InAs layer is tailored by external gate biases. This InAs active layer is sandwiched between top aluminum strip antennas and a bottom gold substrate, forming the metal–insulator–metal configuration. The change of the charge carrier concentration gives rise to modulation of the amplitude and phase of reflected light in a mid-infrared regime. Numerical investigations show the reflectivity contrast of 44%P with biases of −2.5–0 V and the phase change of 236° with biases of −15 V to +15 V at the wavelength of ∼5 μm. Versatile wavefront shaping such as beam focusing with Fresnel Zone plate and beam steering with saw-tooth phase grating is also provided.
Two-dimensional beam steering with tunable metasurface in infrared regime
Authors: Kim Sun Il , Park Junghyun , Jeong Byung Gil , Lee Duhyun , Yang Ki-Yeon , Park Yong-Young , Ha Kyoungho , Choo Hyuck 
Published: February 2022

Abstract
Tunable metasurfaces can change the optical properties of incident light at will such as amplitude, phase, and polarization in a time-dependent fashion. Ultrafast switching speed and the ability for the pixel size reduction of the tunable metasurface can allow various applications such as light detection and ranging, interferometric sensors, and free space optical communications, to name a few. Although there have been successful demonstrations of the wavefront shaping using the tunable metasurface, the implementation of the two-dimensional metasurface pixel array that can be individually addressed in the optical frequency regime still remains challenging. Here, we present the experimental demonstration of the two-dimensional beam steering with the metasurface array by the binary phase grating in the infrared regime. The metasurface unit cell is composed of metal–dielectric–oxide structure with the indium tin oxide as an active layer, which is modulated by using the top fan-out electrodes. The metasurface array is two-dimensionally pixelated and has the phase change above 137° in the infrared regime.
The crystal structure of 1-methyl-2-nitro-1H-imidazole 3-oxide, C4H5N3O3
Authors: Yuan Jun , Wu Bingheng , Wang Yong , Wang Jianlong , Cao Duanlin , Chen Lizhen 
Published: February 2022

Abstract
C4H5N3O3, monoclinic, P21/n (no. 14), a = 8.4556(2) Å, b = 7.0609(3) Å, c = 9.5928(4) Å, β = 90.12(2)°, V = 572.73(4) Å3, Z = 4, R

gt
(F) = 0.0339, wR

ref
(F
2) = 0.0914, T = 140.0 K.
The crystal structure of 2-carboxyl-4-nitroimidazole monohydrate, C4H5N3O5
Authors: Wan Changyuan , Yuan Jun , Wang Yong , Qiao Yanan 
Published: February 2022

Abstract
C4H5N3O5, triclinic,

P

1
‾

$P\overline{1}$

(no. 2), a = 6.3017(7) Å, b = 6.9235(7) Å, c = 8.2333(8) Å, α =100.604(3)°, β = 90.862(4)°, γ = 108.102(4)°, V = 334.60(6) Å3, Z = 2, R

gt
(F) = 0.0616, wR

ref
(F
2) = 0.1414, T = 170.0 K.
Optimum research on the temperature of the ship stern-shaft mechanical seal end faces based on finite element coupled analysis
Authors: Yan Guoping , Xiao Lan , Zhong Fei , Lin Weiguo 
Published: February 2022

Abstract
Due to the complicated working conditions of the ship stern-shaft mechanical seals, it is very difficult to evaluate and optimize the temperature on the sealed end faces. In the paper, one FEA model of the small taper convergent stern-shaft mechanical seals was put forward, and the nonlinear end-face liquid film pressure distribution was derived from different end-face gaps based on the simplified Reynolds equation as the end-face input parameters in FEA model. To prove the correction of the FEA results, one experiment was designed and completed. At the same time, combined with a parametrically coupled FEA model and an orthogonal experimental design, one PSO-BP-GA method based on the combination of particle swarm optimization (PSO), BP neural network and genetic algorithm (GA) was proposed to optimize the temperature of the sealed end faces. The results show that aiming at the prediction accuracy of the temperature on the sealed end faces, the PSO-BP algorithm is higher than BP algorithm and GA-BP algorithm, which error interval is shortened about 40% and 29%, respectively. Subsequently, PSO-BP-GA algorithm is obviously better than BP-GA algorithm and GA-BP-GA algorithm, which validates its effectiveness and feasibility. It will help to lay a theoretical foundation for temperature evaluation on the sealed end faces.
Significance of magnetic field and chemical reaction on the natural convective flow of hybrid nanofluid by a sphere with viscous dissipation: A statistical approach
Authors: Venkateswarlu Avula , Suneetha Sangapatnam , Babu Macherla Jayachandra , Kumar Jorige Girish , Raju Chakravarthula Siva Krishnam , Al-Mdallal Qasem 
Published: February 2022

Abstract
Hybrid nanofluid, which is a combination of Propylene Glycol (PG) – Water (H2O) admixture and paraffin wax and sand, may be utilized as a standby for PG and (H2O) blend in solar thermal framework. Objective of this article is the exploration of the dissipative flow propylene-glycol and water mixture based hybrid nanofluid by a sphere with chemical reaction and heat source parameters. MATLAB in-built solver bvp4c is utilized to exhibit the impacts of various parameters on regular profiles including temperature. Correlation coefficient is utilized to elucidate the impact of pertinent parameters on engineering parameters of concern, such as, surface friction factor. Main findings of this work are magnetic field is having a negative association with friction factor and chemical reaction is consuming a significant positive relationship with Sherwood number. It is witnessed that heat source and Eckert number are useful to meliorate the fluid temperature. Furthermore, validation is performed among our results and earlier published outcomes. Good agreement is detected.
Hexabenzocoronene functionalized with antiaromatic S- and Se-core-modified porphyrins (isophlorins): comparison with the dyad with regular porphyrin
Authors: Kuznetsov Aleksey E. 
Published: February 2022

Abstract
The important and perspective molecular building blocks composed of hexaphenylbenzenes (HPBs) or their oxidized derivatives, hexa-peri-hexabenzocoronenes (HBCs), and metalloporphyrins have recently received significant attention of the researchers. In this study, motivated by recent findings, we have addressed the modifications of structures and properties of HBC-porphyrin compounds by using instead of aromatic porphyrins antiaromatic 20π isophlorin derivatives of thiophene or selenophene. We have reported the first comparative computational investigation of the following systems: (i) HBC with one non-metallated aromatic porphyrin, P(N4H2), unit, HBC-P(N4H2), (ii) HBC with one S-core-modified antiaromatic porphyrin (S-isophlorin), PS4, unit, HBC-PS4, and (iii) HBC with one Se-core-modified antiaromatic porphyrin (Se-isophlorin), PSe4, unit, HBC-PSe4. The study has been done employing the B3LYP/6-31G* approach (in the gas phase and in the implicit solvents, benzene and dichloromethane), and comparison with the B3LYP/6-31G** and B3LYP/6-311G* approaches was performed, where relevant. The effects of the core-modified antiaromatic isophlorins on the structures, electronic, and other properties, potentially including reactivity, of the whole building block HBC-isophlorin have been shown to be quite pronounced and to be noticeably stronger than the effects of the original aromatic non-metallated porphyrin. Thus, we have demonstrated theoretically that the complete porphyrin core-modification with other elements, this time with S and Se leading to the formation of the antiaromatic isophlorins, should be considered as a promising way for modifying and tuning structures, electronic properties and reactivity of the hexabenzocoronene-porphyrin(s) building blocks.
Analysis on the speed properties of the shock wave in light curtain
Authors: Chen Ding , Mu Di , Chen Dachuan , Ni Jinping 
Published: February 2022

Abstract
In this study, we propose an improved measurement method based on light-curtain sensor, and it can obtain the hitting coordinates of supersonic projectile in a larger dispersion area. First, we analyze the speed properties of the shock wave in an effective detection area (also called light curtain in our field), and then find their change rules related to several key factors, including flight speed of the projectile, its attitude, shape, and the temperature in the testing environment. Next we improve a measurement system using wide-angle light-curtain sensor combined with calibration device of the shock speed; especially, this device with three parallel laser beams can effectively measure the shock speed in the light curtain. According to the related structural relation, we derive several computational formulas combined with the shock speed to obtain the hitting position of the measured projectile. Through live ammunition experiments, the results show that the proposed method is feasible and reliable for the supersonic projectile. Besides high accuracy, it also has many advantages, such as fewer sensors, lower requirement for installation, and larger detection area, by comparison with previous measurement systems.
Review of methods and technologies for the enrichment of low-grade phosphorites
Authors: Raiymbekov Yerkebulan , Besterekov Uilesbek , Abdurazova Perizat , Nazarbek Ulzhalgas 
Published: February 2022

Abstract
The article presents the results of generalization of known information on various methods of enrichment of low-grade phosphate raw materials in the world. Based on the review of literature materials, scientists propose several methods of enrichment: mechanical, calcination at high temperatures, flotation, chemical enrichment with various acids and salts. Analyzing and summarizing these data, the article describes the advantages and disadvantages of each proposed method of enrichment of low-grade phosphorites. It is known that the sphere of production of phosphorus-containing products is important for many agricultural countries that produce these products themselves or import from others. This review material is very important for those who are interested in the problems of attracting low-grade phosphates into the production cycle by enriching them.