bluuebunny/crossref_metadata_2025_split huggingface dataset:
Compact phase comparison system for the synthetic HCOOH laser diagnostic system in HL-2A
Authors: Zhang W. , Wu T.Y. , Li Y.G. , Zhang Y.P. 
Published: September 2022

Abstract
Recently, a synthetic formic-acid laser diagnostic system
has been deployed in HL-2A tokamak. However, the main electronics of
the subsystems were discrete devices, and multimodal data analysis
remained out of reach. In this work, we developed a novel compact
high sensitivity Phasemeter (CHSP) system to integrate
interferometer, far-forward collective scattering diagnostic (FCS),
and Faraday effect polarimeter. It provides a framework for
real-time intelligent diagnosis such as plasma disruptions
prediction. We also propose a Synchronous Fast Fourier Transform
(SFFT) method for suppression of spectral leakage and noise
reduction. Experimental results indicate that the electronics system
accuracy is about 1.0× 1015/m-3, which fully meets
the requirements of HL-2A. This work represents a crucial step
toward a high-performance intelligent diagnosis in HL-2A.
Seismic Analysis of Diagrid Structure on Sloping Ground
Authors: Shylaja N , Ashwini R M , Babu E R 
Published: September 2022

Abstract
Lateral efficiency of a building is very important in high-rise buildings, when it comes to building them on sloping ground it is highly required to design the structure for wind load and earthquake loads. The diagrid structure thus provides very high lateral stability and reduces the lateral displacement of the building. In recent years the diagrid structure has attracted many researchers and scholars due to this greater structural efficiency. Diagrid structural system has evolved to be structurally the most efficient, aesthetically pleasant and highly economical. The present paper involves the study of diagrid structure on sloping ground and comparing it with the conventional system and finding the optimum angle of diagrid on different slopes of ground. A 12- storey building is used for comparing diagrid structure and conventional structure on sloping ground, a 48 storey building is used to find out the optimum angle of diagrid on sloping ground, ETABS software Is used for modelling and analysis, response spectrum method is used for analysis, the results show that diagrid structure is more efficient than conventional structure on sloping ground, and the optimum angle of diagrid lies between 60-75° on sloping ground.
Compressive strength of recron fibred cement mortar by replacement of cement with alccofine
Authors: Deshpande A S , Nanjunda K N , Kavyashree B 
Published: September 2022

Abstract
In India, masonry structures are still practiced on major scale. Causalities majorly happens in masonry structures during earthquakes in earthquake prone zones due to less bond strength and non-structured designs. The main aim of afore mentioned paper is to find solution to increase this compressive strength, so that practice of masonry structures in rural area can made safe and economic with respect to strength. This study of bond strength can be carried out by analytic approach as well as experimental approach. In analytic approach, finite element method is used for the study, which requires large numbers of properties to model materials, which are not available in literature for the Indian scenario because literature focuses about results not properties. Hence this compressive strength study is carried out by experimental approach to give it more practical and meaningful direction. In mortar, arbitrarily dispersed fibers and alccofine 1203 are generally used for fortification to resist proliferation of crack and also helps to improve strength and ductility behavior which will help the structure to get less damage and to enhance the performance during earthquakes in earthquake prone zones. This will reduce the causalities. The use of recron 3s fibers is economic and alccofine 1203, easy to practice and effective approach as well. These experimental studies are started by making mortar cubes and ended up with making masonry prism and columns by using recron 3s fibers and alccofine 1203 with different mortar bed thicknesses. The studies on brick masonry prism suggests that use of recron 3s fiber and alccofine 1203 in mortar can increase the compressive strength to enhance the performance of the masonry structure. Use of 8 mm thick mortar bed gives more convincing when compressive strengths of masonry wallets are compared.
Catalytic mechanism and activity of N2 reduction on boron-decorated crystalline carbon nitride
Authors: Zheng Mei , Cai Xu , Li Yi , Ding Kaining , Zhang Yongfan , Chen Wenkai , Sun Chenghua , Lin Wei 
Published: September 2022

Abstract
The development of efficient, low-cost, and eco-friendly catalysts for nitrogen fixation is essential and provides an alternative method to the traditional Haber–Bosch process. However, studies on thermal catalyst of nitrogen fixation mainly focus on metal-containing, and the microscopic mechanism of thermal reduction process is still limited. Herein, we explored an economic metal-free boron atom decorated poly(triazine imide) (B/PTI), a crystalline carbon nitride, as an excellent thermal catalyst of nitrogen fixation and proposed a substrate-hydrogen mechanism for the N2 thermal reduction reaction (NTRR). Our results reveal that the substrate hydrogen as the hydrogen source can promote the hydrogenation process with activation barrier of 0.56 eV, significantly lower than that of reported NTRR catalysts. Importantly, the B/PTI exhibits high turnover frequency, which is comparable to Fe, Ru, and Ti catalysts. Our work offers new insights into NTRR mechanism and provides an alternative solution for the sustainable ammonia synthesis.
New chromium steel grade for creep applications
Authors: Callejo Lorena M , Barbero José Ignacio , Serna-Ruiz Mónica , Eguizabal David , Martinez Roberto Fernandez , Jimbert Pello , Calleja-Saenz Beatriz , López Alejandra 
Published: September 2022

Abstract
In this study, a novel Chromium steel grade (COIN2) is produced as a result of a new steel composition and an innovative heat treatment. This new steel grade COIN2 evolves from the P92 steel grade and other novel steel grade recently created by the authors (COIN), and represents an enhancement of hardness, tensile properties, and creep behaviour with respect to them, which validates the metallurgical strategy used for further research in order to increase the efficiency of power plants and thus reduce the CO2 emissions. The characterization reveals a significant property improvement with the innovative thermal treatment, contributing to the production of a novel and more competitive steel grade for creep applications.
The emergence of AntibodyPlus: the future trend of antibody-based therapeutics
Authors: Zhu Yong , Wang Shawn Shouye , Zhou Zhaohui Sunny , Ho Mitchell 
Published: September 2022

Abstract
To date, close to 100 canonical monoclonal antibody drugs have been approved by the FDA; furthermore, a number of antibody-derived therapeutics in nontraditional formats have reached late development stages and the market, and many more are being evaluated in early-stage development. To better reflect this trend and to set up a framework for forward thinking, we herein introduce the concept of AntibodyPlus, embracing any therapeutics with an antibody component. AntibodyPlus therapeutics contain effector modules, in the form of small molecules, nucleic acids, proteins or even cells, to enhance their therapeutic activities against cancer, virus infection and other diseases. In this short review, we discuss historic perspective and current status of therapeutic antibody development, and the scope and categories of AntibodyPlus therapeutics along with their advantages, applications and challenges. We also present several examples that highlight their design principles, potentials and future trends.
Homologue series detection and management in LC-MS data with homologueDiscoverer
Authors: Mildau Kevin , van der Hooft Justin J J , Flasch Mira , Warth Benedikt , El Abiead Yasin , Koellensperger Gunda , Zanghellini Jürgen , Büschl Christoph 
Published: September 2022

Abstract

Summary
Untargeted metabolomics data analysis is highly labour intensive and can be severely frustrated by both experimental noise and redundant features. Homologous polymer series is a particular case of features that can either represent large numbers of noise features or alternatively represent features of interest with large peak redundancy. Here, we present homologueDiscoverer, an R package that allows for the targeted and untargeted detection of homologue series as well as their evaluation and management using interactive plots and simple local database functionalities.

Availability and implementation
homologueDiscoverer is freely available at GitHub https://github.com/kevinmildau/homologueDiscoverer.

Supplementary information
Supplementary data are available at Bioinformatics online.
CarcinoHPVPred: An ensemble of machine learning models for HPV carcinogenicity prediction using genomic data
Authors: Karamveer Karamveer , Tiwary Basant K 
Published: September 2022

Abstract
Human papillomavirus (HPV) infections often show no symptoms but sometimes lead to either warts or carcinoma based on the HPV genotype. The relationship between HPV infections and cervical cancer have been well studied in the past two decades. However, distinguishing carcinogenic HPV variants from non-carcinogenic ones remains a major challenge in clinical genetic testing of HPV-induced cancer samples. All of the published HPV carcinogenicity prediction methods are neither publically available nor tested with two-thirds of available HPV variants. The nucleotide composition-based studies are the simplest and most precise methods of characterizing new genomes. Hence, there is a need for machine learning models which can predict the carcinogenic nature of newly discovered HPV based on their genomic composition. We developed a standalone and web tool, CarcinoHPVPred (h t t p :// test5.bicpu.edu.in/CarcinoHPVPred.php), for predicting the phenotype of HPV with a range of a high accuracy between 94% - 100%. This tool consists of machine learning models build upon genomic features of two genes namely E2 and E6. Overall, the accurate and early prediction of carcinogenic nature of HPV can be performed with this only available tool of its kind till date.
A totally endoscopic approach for aortic valve surgery
Authors: Yilmaz Alaaddin , Van Genechten Silke , Claessens Jade , Packlé Loren , Maessen Jos , Kaya Abdullah 
Published: September 2022

Abstract

OBJECTIVES
Our goal was to describe a new approach for totally endoscopic aortic valve replacement.

METHODS
From October 2017 through December 2020, a total of 266 consecutive patients underwent totally endoscopic aortic valve replacement. Reoperations and combinations were excluded.

RESULTS
A total of 266 patients with a median age of 72 (64, 79) years underwent totally endoscopic aortic valve replacement; of these, 250 (93.98%) patients were designated to undergo surgery because of aortic valve stenosis. The median follow-up index was 0.69 (0.30, 0.90). Major adverse cardiac and cerebrovascular events occurred in 4 (1.50%) patients within 30 days. Overall hospital mortality was 1.50%. Twenty additional deaths (7.52%) occurred during the 3-year follow-up period. An early thoracoscopic revision was needed in 7 patients due to signs of bleeding or cardiac tamponade. Fourteen patients required a permanent pacemaker implant.

CONCLUSIONS
Retrospective analysis of our early experience with totally endoscopic aortic valve replacement in 266 consecutive patients demonstrated satisfactory results, with low mortality and acceptable morbidity rates.
Discordance of apolipoprotein B with low-density lipoprotein cholesterol or non-high-density lipoprotein cholesterol and coronary atherosclerosis
Authors: Su Xin , Cai Xueli , Pan Yuesong , Sun Jingping , Jing Jing , Wang Mengxing , Meng Xia , Wang Yongjun , Wei Tiemin , He Yan 
Published: September 2022

Abstract

Aims
High level of apolipoprotein B (Apo B) is associated with incident subclinical atherosclerosis. The present study evaluated the associations between discordant Apo B with low-density lipoprotein cholesterol (LDL-C), non-high-density lipoprotein cholesterol (non-HDL-C), and coronary atherosclerotic burden.

Methods and results
This study enrolled 3043 participants aged 50–75 years from the PolyvasculaR Evaluation for Cognitive Impairment and vaScular Events (PRECISE) study that was conducted in the community in Lishui City, China. Discordant Apo B with LDL-C and non-HDL-C were defined by residuals and medians. Coronary atherosclerotic burden was evaluated by segment involvement score (SIS) and segment stenosis score (SSS) which were determined by computed tomography angiography. We performed discordance analyses examining associations of discordant Apo B with LDL-C or non-HDL-C with the coronary atherosclerotic burden. The mean age of participants was 61.2 ± 6.7 years, 53.6% were females. Participants with discordant high Apo B relative to non-HDL-C were at higher odds of plaques [odds ratio (OR), 1.30; 95% confidence interval (CI), 1.08–1.57], SIS [common odds ratio (cOR), 1.35; 95% CI, 1.14–1.60], and SSS (cOR, 1.40; 95% CI, 1.18–1.67) compared with concordant group. However, discordantly low Apo B with non-HDL-C was associated with decreased odds of the coronary atherosclerotic plaques and its burden. Similar results were shown for discordant analyses for Apo B with LDL-C.

Conclusion
Discordantly high Apo B with LDL-C and non-HDL-C were associated with an increased odds of the coronary atherosclerotic plaques and its burden. These findings highlighted the importance of Apo B for primary prevention of coronary atherosclerosis.
Volatiles released byBeauveria bassianainduce oviposition behavior in the fall armywormSpodoptera frugiperda(Lepidoptera: Noctuidae)
Authors: Ramírez-Ordorica Arturo , Contreras-Cornejo Hexon Angel , Orduño-Cruz Nuvia , Luna-Cruz Alfonso , Winkler Robert , Macías-Rodríguez Lourdes 
Published: September 2022

AbstractMicrobial volatile organic compounds may act as semiochemicals, inciting different behavioral responses in insects. Beauveria bassiana is an entomopathogenic fungus, and physiological and environmental factors are positively related to fungal virulence. In this study, we examined the volatile profiles produced by eight B. bassiana strains, isolated from soil plots and mycosed insect cadavers, with different speeds of kill and determined if these compounds induce oviposition behavior in Spodoptera frugiperda. Fungal volatilome analysis revealed differences between the isolates. Isolates from mycosed insects showed higher virulence, larger egg mass area and length, and a higher number of eggs by mass, than those obtained from soil. Furthermore, a dilution of the fungal odoriferous compounds increased the insect response, suggesting that S. frugiperda is highly susceptible to the fungal compound’s fingerprint. Otherwise, the insect response to the natural blend of volatiles released by the fungus was different from that obtained with 3-methylbutanol, which was the most abundant compound in all isolates. The ability of an entomopathogen to produce volatiles that can induce olfactory stimulation of egg-laying behavior could represent an ecological adaptive advantage in which the entomopathogen stimulates the insect population growth.
Outsourcing Issues of Wood Supply Chain Management in the Forest Industry
Authors: Palander Teijo 
Published: September 2022

Abstract
Supply-chain management of the forest industry focuses on improving client services which requires efficient collaboration between organizations in practice. Therefore, collaboration of third party logistics (3PL) and fourth party logistics (4PL) companies were analyzed using a survey and the inductive organizational gap-analysis. The supply-chain companies of the 3PLs asked for better quality information from client factories for improving logistics. They also needed online information for improving the quality control of logistics provided by their subcompanies. In addition to the quality, all companies (3PL, 4PL, clients) will need new information technology for synchronizing supply-chain operations efficiently. In this respect, the findings show how 3PLs want to adopt 4PL’s coordination mechanism for creating advanced collaboration on triadic relationships of the companies. This knowledge can be used by industry in engineering the 3PL and 4PL towards franchise-provided multiclient supply chains; cloud-service applications of collaboration groups for synchronizing wood-harvesting and transportation operations are especially important in the future. Implications of this background theory for practice are discussed mainly from perspective of decentralized wood procurement.
A high-quality chromosome-level genome assembly of the bivalve mollusk Mactra veneriformis
Authors: Sun Yongxin , Liu Xiangfeng , Xie Xi , Bai Yongan , Wang Shuo , Teng Weiming , Li Dacheng , Li Hualin , Yu Zuoan , Zhang Ming , Zhou Zunchun , Liu Xu , Nie Hongtao , Du Shaojun , Li Xiaodong , Li Qi , Wang Qingzhi 
Published: September 2022

Abstract
Mactra veneriformis (Bivalvia: Mactridae) is a bivalve mollusk of major economic importance in China. Decreased natural yields of M. veneriformis have led to an urgent need for genomic resources. To address this problem and the currently limited knowledge of molecular evolution in this genus, we here report a high-quality chromosome-level genome assembly of M. veneriformis. Our approach yielded a 939.32 Mb assembled genome with an N50 contig length of 7,977.84 kb. Hi-C scaffolding of the genome resulted in assembly of 19 pseudochromosomes. Repetitive elements made up ∼51.79% of the genome assembly. A total of 29,315 protein-coding genes (PCGs) were predicted in M. veneriformis. Construction of a genome-level phylogenetic tree demonstrated that M. veneriformis and Ruditapes philippinarum diverged around 231 million years ago (MYA). Inter-species comparisons revealed that 493 gene families have undergone expansion and 449 have undergone contraction in the M. veneriformis genome. Chromosome-based macrosynteny analysis revealed a high degree of synteny between the 19 chromosomes of M. veneriformis and those of Patinopecten yessoensis. These results suggested that M. veneriformis has a similar karyotype to that of P. yessoensis, and that a highly conserved 19-chromosome karyotype was formed in the early differentiation stages of bivalves. In summary, the genomic resources generated in this work serve as a valuable reference for investigating the molecular mechanisms underlying biological functions in M. veneriformis and will facilitate future genetic improvement and disease treatment in this economically important species. Furthermore, the assembled genome greatly improves our understanding of early genomic evolution of the Bivalvia.
Development and Validation of a Japanese Version of the Inflammatory Bowel Disease Self-efficacy Scale and Cross-culture Study in Japan and the United States
Authors: Tanaka Makoto , Kawakami Aki , Sakagami Kayoko , Terai Tomoko , Fernandez Jovelle , Keefer Laurie , Ito Hiroaki 
Published: September 2022

Abstract

Background
Self-efficacy is an important health outcome for patients with inflammatory bowel disease (IBD). We aimed to develop a Japanese version of the IBD-Self-Efficacy Scale (IBD-SES.J) and compare characteristics of self-efficacy of IBD patients with previously reported results from patients in the United States.

Methods
We conducted a questionnaire survey of patients with IBD from a specialized IBD clinic and respondents recruited online. Self-efficacy of patients in Japan and the United States were compared by Student t test and Cohen d coefficient to gauge effect size.

Results
A total of 919 valid responses were obtained: 482 patients from the specialized IBD clinic and 437 patients from the online survey. Significant differences (P &lt; .01) were observed in the following 3 subscales: “managing stress and emotions,” “managing symptoms and disease,” and “maintaining remission” when comparing remission and active periods; and known-group validity was mostly confirmed. Cronbach’s alpha coefficients of each subscale ranged between 0.85 and 0.94. Intraclass correlation coefficients (95% confidence intervals [CIs]) to assess test-retest reliability of each item were between 0.56 (95% CI, 0.47-0.64) and 0.78 (95% CI, 0.73-0.82). Self-efficacy scores for most items in Japanese patients with IBD were lower compared with patients in the United States, with moderate effect size (Cohen d &gt; 0.5), especially in the subscale “managing stress and emotions.”

Conclusions
The study demonstrates the reliability and validity of the IBD-SESJ. Self-efficacy scores for most items in Japanese patients were lower than those of patients in the United States. Further investigation is required to understand cross-cultural score differences.
Recovery of a space-time-dependent diffusion coefficient in subdiffusion: stability, approximation and error analysis
Authors: Jin Bangti , Zhou Zhi 
Published: September 2022

AbstractIn this work we study an inverse problem of recovering a space-time-dependent diffusion coefficient in the subdiffusion model from the distributed observation, where the mathematical model involves a Djrbashian–Caputo fractional derivative of order $\alpha \in (0,1)$ in time. The main technical challenges of both theoretical and numerical analyses lie in the limited smoothing properties due to the fractional differential operator and high degree of nonlinearity of the forward map from the unknown diffusion coefficient to the distributed observation. We establish two conditional stability results using a novel test function, which leads to a stability bound in $L^2(0,T;L^2(\varOmega ))$ under a suitable positivity condition. The positivity condition is verified for a large class of problem data. Numerically, we develop a rigorous procedure for recovering the diffusion coefficient based on a regularized least-squares formulation, which is then discretized by the standard Galerkin method with continuous piecewise linear elements in space and backward Euler convolution quadrature in time. We provide a complete error analysis of the fully discrete formulation, by combining several new error estimates for the direct problem (optimal in terms of data regularity), a discrete version of fractional maximal $L^p$ regularity and a nonstandard energy argument. Under the positivity condition, we obtain a standard $\ell ^2(L^2(\varOmega ))$ error estimate consistent with the conditional stability. Further, we illustrate the analysis with some numerical examples.
The value of community-integrated health information exchanges: three recent examples from El Paso, Texas
Authors: Sloan-Aagard Chantel , Helgesen Wanda , Nañez Juan , Law Jon , Currey J C , Meils Jacob , Bishop Joel , Hartmann Emily 
Published: September 2022

Abstract
The foundational role of health information exchanges (HIEs) is to facilitate communication between clinical partners in real time. Once this infrastructure for the secure and immediate flow of patient information is built, however, HIEs can benefit community public health and clinical care in myriad other ways that are in line with their mission, goals, patient privacy, and funding structures. We encourage the development of community-integrated HIEs and list specific steps that can be taken toward community integration. We give three examples of those steps in action from a community HIE in El Paso, TX. Each local partnership, in combination with technology innovation, resulted in the development of informatics tools to address community health needs and generated long-term benefits, especially for the most vulnerable patients. Two examples relate to different aspects of the COVID-19 pandemic and a third to the Afghan refugee evacuation.