bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative Proteomics Analysis of Hylarana erythraea (Schlegel, 1837) (Anura: Ranidae) Skin Secretion from Disturbed and Undisturbed Habitats
Authors: Ong Dasi , Ismail Mohd Nazri , Shahrudin Shahriza 
Published: November 2022

Abstract
Hylarana erythraea lives in disturbed and undisturbed habitats, making them vulnerable to predators and pathogens. This study aims to compare skin secretion’s protein profile of H. erythraea from disturbed (Jetty Kuah and Kampung Bohor Chempedak) and undisturbed (Temurun and Telaga Tujuh waterfall) habitats using Orbitrap-Liquid Chromatography-Mass Spectrometry/Mass Spectrometry analysis. Four H. erythraea individuals were caught in disturbed and undisturbed areas. The total protein concentration for disturbed and undisturbed H. erythraea individuals was 0.4976 mg/mL and 0.0404 mg/mL. In disturbed individuals, we identified a total of 114 proteins. In contrast, only 81 proteins were identified in undisturbed individuals. A total of 32 similar proteins can be found in both fractions. Eighty-two proteins, including 32 antimicrobials, are unique to H. erythraea from disturbed habitat, while 42 proteins, including eight antimicrobials from undisturbed habitat. Overall, H. erythraea from disturbed habitats has a higher protein content and antimicrobials than undisturbed habitats. This is because prolonged exposure to disturbances triggers a stress response at the physiological level, producing higher protein and antimicrobials. Other than antimicrobials, H. erythraea from disturbed areas has a much higher structural protein to serve as a different physical survival skill. This is because different habitat environments have different variables that affect protein expression in skin secretion.
Ν-Methyl-D-aspartate antagonists and their role in limiting ototoxic phenomena
Authors: Pavlidis Pavlos , Papadopoulou Kyriaki , Tseriotis Vasilis Spyridon , Karachrysafi Sofia , Sardeli Chrysanthi , Malliou Faye , Kavvadas Dimitrios , Papamitsou Theodora , Sioga Antonia , Anastasiadou Penelope , Kouvelas Dimitrios 
Published: November 2022

Abstract
Our aim was to test whether amikacin's well-known cochleotoxic effects could be suppressed, depending on whether an NMDA-antagonist (memantine) was administered simultaneously with or after amikacin treatment. Forty Wistar rats were used in this experiment. Ten rats acted as controls and received no medication (group A). Amikacin (200 mg/kg) was administered intraperitoneally (i.p.) once daily for 14 days to 10 animals in group B; amikacin (200 mg/kg) was administered concurrently with memantine (10 mg/kg, i.p., once daily) to another 10 animals in group C. In Group D a final 10 animals were given memantine (10 mg/kg, once daily) intraperitoneally for 14 days following a 2-week amikacin treatment. The cochlear activity of the right ear was tested using DPOAE in conscious animals. All animals were sacrificed at the conclusion of the experiment and both cochleae were collected for histological and immunohistochemical analysis. All groups treated with amikacin showed decreased cochlear activity, as testified by decreased DPOAE-amplitudes, compared to the pre-treatment state. In group B rats, the DPOAE reduction was more pronounced. On histologic examination, the cochlear structures of group C rats and, although to a lesser extent, group D rats showed less severe cochlea damage. Memantine plays a protective role, resulting in restoring partially cochlear structures when administered either simultaneously with or after completion of amikacin i.p. treatment in rats.
Knowledge, attitude, and practices regarding the COVID-19 pandemic among Ruminant and Exotic Animal farmers in Selangor, Malaysia
Authors: Sadiq Mohammed Babatunde , Ahmad Nur Indah , Mansor Rozaihan 
Published: November 2022

Abstract
The COVID-19 pandemic has had a remarkable impact on human lives and livelihoods, including livestock farmers and exotic animal owners. This study aims to assess the knowledge, attitude, and practices regarding the COVID-19 pandemic among ruminant and exotic animal farmers in Selangor, Malaysia. Using a quantitative research methodology, an online-based and face-to-face survey was conducted among 102 farmers. Data were analysed using descriptive statistics and binary logistic regression models. Overall, slightly more than half of the respondents demonstrated good knowledge of and attitude towards COVID-19 and its potential zoonotic implications. Likewise, 58.4% of the respondents exhibited satisfactory preventive practices against potential exposure to COVID-19 except for the low usage of hand gloves and facemasks when handling animals. Farmers’ knowledge of COVID-19 was associated with increasing age (Odds ratio; OR = 1.06; 95 % Confidence Interval: CI 1.01-1.11) and those that kept exotic animals (OR = 10.84; 95% CI 2.32-50.70) relative to ruminant farmers. Respondents were more likely to engage in preventive practices against COVID-19 as their age increased (OR = 3.72; 95% CI 2.54-6.21), and a tendency (P = 0.08) for better preventive practices among farmers with lower (1-5 years) years of farming experience (P = 0.02; OR = 3.77; 95% CI 1.15-12.34). These findings highlight the need to improve farmers’ knowledge and attitude towards COVID-19 and encourage them to adhere to recommended preventive measures. The associated factors might be considered in improving livestock farmers’ knowledge of COVID-19 and promoting their adherence to recommended guidelines during farm operations.
Identification of differentially expressed genes associated with ferroptosis in Crohn’s disease
Authors: Zhang Wenquan , Li Zhaoshui , Li Hongbo 
Published: November 2022

Abstract
Objective:Ferroptosis-related genes may have a critical regulatory role in the pathogenetic process of Crohn’ disease(CD).The purpose of this study was to identify genes expressed in CD that are associated with ferroptosis and provide direction in the diagnosis and therapy of Crohn's disease.
Methods: The data for CD mRNA expression were first gathered from the Gene Expression Omnibus (GEO) database, and two gene sets were selected as major targets (GSE75214 and GSE102133) and analyzed differentially expressed genes.Next,R software (version 4.1.2) was used to analyze the common genes in CD differential expressed genes and ferroptosis-related genes.GO enrichment analysis,KEGG pathway analysis were used to identify differential related pathways and functions.Protein-protein interaction(PPI) analysis was performed to identify target genes.DSigDB website was used to predict potential target drugs for hub genes.Finally, qRT-PCR method were used to detect the expression of these ferroptosis related genes in clinical samples obtained from healthy control and CD patients.
Result: According to two GEO datasets, we finally identified 13 ferroptosis DEGs(10 upregulated genes and 2 downregulated genes) in crohn disease with the threshold of p-value < 0.05 and |log2 FC| > 1 and selected for continued analysis.Go enrichment analysis and KEGG pathways results were shown in the following figures.PPI analysis indicate the mutual effect between these genes and filtered out 5 hub genes.Top 10 potential targeted drugs were selected. Finally, the result of qRT-PCR shown that the expression of three genes IL-6,PTGS2 and DUOX2 were different between CD samples and healthy samples.This result was consistent with the results we obtained in the biological information analysis.
Conclusion: Bioinformatics analysis identified a total of 13 iron death-associated genes in CD. Three differential genes IL-6,PTG32 and DUOX2 were detected in tissue experiments.Our findings might provide new biomarkers and promising treatment targets in CD.
New Technique Used for Strengthening Jack Arch Slab
Authors: AL-KHAZRAJI Hayder , Jaafer Abdulkhaliq A. , HAIDAR Haider H. , Mozan Majed Ali , Faraj Haider Sattar , Maktuf Sajjad Sadiq 
Published: November 2022

Abstract
The use of fiber-reinforced polymer rope (FRPR) increases the seismic performance of clay-brick unreinforced masonry slabs and increases the flexural strength of jack arch slabs or roofs. This study examines the bond strength between the clay brick units that make up the jack arch slab and strengthens it using fiber-reinforced polymer rope (FRPR) utilizing a load deflection test. Various parameters were studied, clay brick types affected, span length, camber high and number of injection point (i.e. number of FRPR strengthening are used for each span). The results show the bond strength for jack arch specimens at mid-span for two solid and perforated clay brick slabs gives the most flexural failure. In addition, the increase in the performance of jack arch slabs under line loading (i.e. it is higher deflection) with camber and number of injection.
A method based on k-shell decomposition to identify influential nodes in complex networks
Authors: HamaKarim Bakhtyar Rafeeq , Mohammadiani Rojiar Pir , Sheikhahmadi Amir , Hamakarim Bryar Rafeeq 
Published: November 2022

Abstract
Finding the most influential nodes in complex networks is one of the open research issues. This problem can be divided into two sub-problems: (1) identifying the influential nodes and ranking them based on the individual influence of each node and (2) selecting a group of nodes to achieve maximum propagation in the network. In most of the previous articles, only one of these sub-issues has been considered. Therefore, this article presents a method to measure the spreading power of influential nodes in the network (the first sub-problem) and select the best group from them (the second sub-problem). In the proposed method, first, the input network is allocated to different communities. Then, the common neighbors and the degrees of the two end vertices of each edge are used to weigh the graph edges in each community. Next, in each of the communities, the nodes' propagation power is measured and ranked. Finally, a group of influential nodes is selected to start the propagation process. Eight data sets collected from real networks have been used for evaluation. The proposed method is compared with other previously known methods based on ranking accuracy, assigning different ranks to nodes, and calculating the amount of diffusion created in the network. The results show the proposed method's significant superiority over other methods in all test datasets.
Lithium and phosphorus-functionalized graphitic carbon nitride monolayer for efficient hydrogen storage: A DFT study
Authors: Gorai Deepak Kumar , Kundu Tarun Kumar 
Published: November 2022

AbstractWe have explored the consequence of lithium and phosphorous functionalization on the graphitic carbon nitride (g-C3N4) monolayer for hydrogen storage using density functional theory. Both pristine and Li and P decorated g-C3N4show a semiconductor nature. The substantial overlap between thesorbital of Li and theporbital of nitrogen near the Fermi level shows the binding between Li and the g-C3N4. The repositioning of HOMO and LUMO is noticed in the Li and P decorated g-C3N4. The Bader charge analysis indicates the charge allocation from the Li and P atom to the g-C3N4, which results in the adsorption of H2by electrostatic interaction. The hydrogen storage capacity of 5.78 wt% is obtained after functionalizing Li and P into the g-C3N4. The obtained adsorption energies for the H2adsorption confirm that Li and P functionalized g-C3N4is a mesmerizing candidate for the reversible loading of H2at ambient conditions.
Enhancing the pitting resistance of AISI 430 stainless steel by laser treatment
Authors: Filatov Ilya , Prokopiev Vladislav , Shchedrina Nadezhda , Suslov Roman , Bogdanov Roman , Bachurina Diana , Davydova Evgenia , Odintsova Galina 
Published: November 2022

Abstract
The paper proposes a method of laser treatment of the steel sur-face for protection against the formation of electrochemical corrosion.AISI 430 stainless steel plates were used in the work. The influ-ence of laser structuring on the contact angle and the interactionof laser-structured steel surfaces with an aggressive environment dur-ing corrosion tests are considered. The composition of oxides formedafter laser treatment, as well as the roughness of the modified sur-face, are considered. Positive dynamics in protection against pittingcorrosion formation on the surface of metals have been revealed.
Exponential and finite/fixed-time synchronization of quaternion-valued Cohen-Grossberg inertial neural networks with proportional-delayed by non-separated method with imperfect order theory
Authors: Xiong Yao , Li Yesheng , Lv Haifei , Xiong Zhonglong , Wu Wei , Xie Songhua , Chen Mengwei , Hu Changkui , Li Min , Chen Wanping 
Published: November 2022

Abstract
In this paper, exponential and finite/fixed-time synchronization of quaternion-valued Cohen-Grossberg inertial neural network with proportional-delayed is investigated. In order to study the convergence of quaternion-value system, we proposed the imperfect order theory. Accordingly quaternion-value Lyapunov function are proposed and utilized to study the synchronization of the neural network. Several lemmas are introduced and proved for the later synchronization study. Unlike the most commonly used separated method for quaternion-value network, with the help of our imperfect order theory, we adopt a non-separated method to construct the controller and analyze the quaternion value Lyapunov function directly. Numerical simulations are presented to indicate the effectiveness of the proposed method.
Kennedy epitope (KE)-dependent retrograde transport of efficiently cleaved HIV-1 envelopes (Envs) and its effect on Env cell surface expression and viral particle formation
Authors: Das Supratik , Parray Hilal Ahmad , Chiranjivi Adarsh Kumar , Bansal Manish , Rathore Deepak Kumar , Kumar Rajesh , Samal Sweety 
Published: November 2022

Abstract

Efficiently cleaved HIV-1 Envs are the closest mimics of functional Envs as they specifically expose only bNAb (broadly neutralizing antibody) epitopes and not non-neutralizing ones, making them suitable for developing vaccine immunogens. We have previously identified several efficiently cleaved Envs from clades A, B, C and B/C. We also described that truncation of the CT (C-terminal tail) of a subset of these Envs, but not others, impairs their ectodomain conformation/antigenicity on the cell surface in a CT conserved hydrophilic domain (CHD) or Kennedy epitope (KE)-dependent manner. Here, we report that those Envs (4 − 2.J41 and JRCSF), whose native-like ectodomain conformation/antigenicity on the cell surface is disrupted upon CT truncation, but not other Envs like JRFL, whose CT truncation does not have an effect on ectodomain integrity on the cell surface, are also defective in retrograde transport from early to late endosomes. Restoration of the CHD/KE in the CT of these Envs restores wild-type levels of distribution between early and late endosomes. In the presence of retrograde transport inhibitor Retro 2, cell surface expression of 4 − 2.J41 and JRCSF Envs increases but particle formation decreases for 4 − 2.J41 and JRCSF Env pseudotyped viruses. Our results show for the first time a correlation between CT-dependent, CHD/KE regulated retrograde transport and cell surface expression/viral particle formation of these efficiently cleaved Envs. Based on our results we hypothesize that a subset of these efficiently cleaved Envs use a CT-dependent, CHD/KE-mediated mechanism for assembly and release from late endosomes.
Spatial and seasonal variations of organic and inorganic pollution parameters and relationship between Malacostraca fauna in the Eastern Black Sea rivers Short Title: The relationship of some Malacostracans with pollutants
Authors: BAYTAŞOĞLU Hazel 
Published: November 2022

Abstract
The aim of this study is to reveal the relationship between Malacostraca species distributed in the eastern Black Sea basin streams and some organic and inorganic pollution parameters. For this purpose, water samples and Malacostraca samples were taken seasonally from 9 stations selected from the basin between 2019–2020. A hand net (D-frame net) was used for biological samples. For the determination temperature, dissolved oxygen, pH parameters were seasonally measured in the field. Measurements for Nitrate, Ammonia, Phosphate were made with spectrophotometer. Metal analyzes in water were performed using Inductively Coupled Plasma Mass Spectrometry. 4 species of Malacostraca have been identified. Environmental parameters and species were evaluated together and it was determined that Asellus aquaticus species was distributed in both clean and partially polluted stations. It has been observed that Potamon ibericum species is sensitive to pollution and prefers clean waters.Gammarus komareki and Gammarus pulex pulex species have been found to tolerate light contamination. In this study, different parameters were examined in the rivers of the eastern Black Sea basin and it was observed that the pollution was low and there were seasonal differences.
Warburg effect secondary to diffuse large B‑cell lymphoma-associated hemophagocytic lymphohistiocytosis: a case report
Authors: Zhou De , Wang Lulu , Zhu Lixia , Yang Xiudi , Xiong Mengqi , Huang Xianbo , Zhu Jingjing , Li Li , Jin Lai , Zheng Wenjun , Cao Lihong , Xie Wanzhuo , Ye Xiujin 
Published: November 2022

Abstract
Background: The increase in glucose consumption during aerobic glycolysis of cancer cells, known as the Warburg effect, is associated with dismal prognosis. Warburg effect secondary to diffuse large B‑cell lymphoma (DLBCL) is rare and there is no specific treatment regimen.
Case presentation: We here described a case of patient who presented with hemophagocytic lymphohistiocytosis and developed hyperlactacemia inducing by Warburg effect, then he was successfully treated by continuous renal replacement therapy (CRRT) and diagnostic chemotherapy. Eventually, he was diagnosed as DLBCL.
Conclusion: Existing evidence shows that Warburg effect can be secondary to diffuse large B-cell lymphoma, CRRT combined with diagnostic chemotherapy was effective in this case. Additive attention should be paid to this phenomenon and effective strategy remains to be explored.
Experimentally simulating the beam shaping capabilities of deformable mirrors using a liquid crystal spatial light modulator
Authors: Scholes Stirling , Mohapi Lehloa , Leach Jonathan , Forbes Andrew , Dudley Angela 
Published: November 2022

Abstract
The number of mirror segments, mirror geometry and orientation are essential parameters when assessing the beam-shaping capabilities of deformable mirrors. Here, we use a Liquid Crystal on Silicon Spatial Light Modulator (LCoS-SLM) to mimic the mechanical design of a deformable mirror and quantitatively analyse the effect of the number of mirror segments and their geometrical structure on resulting structured modes. Our approach can be used as a test bed prior to designing a deformable mirror for high power beam shaping.
Distribution of Anopheles gambiae Thioester-containing Protein 1 Alleles along Malaria Transmission Gradients in The Gambia
Authors: Hamid-Adiamoh Majidah , Jabang Abdoulie , Opondo Kevin Ochieng , Ndiath Mamadou Ousmane , Assogba Benoit Sessinou , Amambua-Ngwa Alfred 
Published: November 2022

Abstract
Background
Thioester-containing Protein 1 (TEP1) is a highly polymorphic gene playing an important role in mosquito immunity to parasite development and associated with Anopheles gambiae sensu lato (s.l.) vectorial competence. Allelic variations in TEP1 could render mosquito either susceptible or resistant to parasite infection. Despite reports of TEP1 genetic variations in An. gambiae s.l., the correlation between TEP1 allelic variants and transmission patterns in malaria endemic settings remains unclear.
Methods
TEP1 allelic variants were characterised by PCR from archived genomic DNA of >1000 An. gambiae s.l. mosquitoes collected between 2009 and 2019 from eastern Gambia, where malaria transmission remains moderate but has been decreasing, and western regions with low transmission.
Results
Eight common TEP1 allelic variants were identified at varying frequencies in An. gambiae s.l from both transmission settings. These comprised the wild type TEP1, homozygous susceptible allele, TEP1s; homozygous resistance alleles: TEP1rA and TEP1rB, and the heterozygous resistance alleles: TEP1srA, TEP1srB, TEP1rArB and TEP1srArB. There was no significant disproportionate distribution of the TEP1 alleles by transmission setting and the temporal distribution of alleles was also consistent across the transmission settings. TEP1s was the most common in all vector species in both settings (allele frequencies: East= 21.4-68.4%. West=23.5-67.2%). In An. arabiensis, the frequency of wild type TEP1 and susceptible TEP1s was significantly higher in low transmission setting than in high transmission setting (TEP1: Z= -4.831, P<0.0001; TEP1s: Z= -2.073, P=0.038).
Conclusions
The distribution of TEP1 alleles does not distinctly correlate with malaria endemicity pattern in The Gambia. Further studies are needed to understand the link between genetic variations in vector population and transmission pattern in this setting.
Analyzing Enactive AI implementations on Enactive AI terms
Authors: Filho Carlos R. Rodrigues , Nogueira Yuri Lenon Barbosa 
Published: November 2022

Abstract
This paper presents a discussion on Enactive Artificial Intelligence about the practical evolution of this field. It has been mostly discussed theoretically, but few are the works that try to implement it. In 2009 were published two paradigmatic works of the field, where the authors state requirements for Enactive Artificial Intelligence and for agency, in an enactive perspective. We take those works and their requirements to analyze other papers that claim to have a practical experiment on Enactive Artificial Intelligence. Although they are a few in number, they made some progress in respect to the requirements. The agency conditions were not really a problem, for almost all works were able to achieve them. On the other hand the Enactive Artificial Intelligence design principles proved to be hard. Only one work was able to implement one of them and none for the other, although one work seems to have a potential to advance in this principle. We conclude that the combination of the works may be the future of the Enactive Artificial Intelligence field.
Implementation of an Octa-band Metamaterial Inspired Frequency Band Reconfigurable Antenna for IoT applications in Wireless Standards
Authors: Saraswat Ritesh Kumar , Kumar Mithilesh 
Published: November 2022

Abstract
This paper propose a multiband antenna with implementation of metamaterial split ring resonator (SRR), quasi complementary split ring resonator (CSRR) and slots to achieve octa-band characteristics for wireless standards. Multiband features is accomplished by implementation of slot approach within radiating section part and loading the SRR, CSRR cell. Proposed design indicates the frequency band reconfigurability nature by using the switching PIN diode putting at the slotted section of ground plane. During OFF state of switching element structure resonating in eight wireless communication bands covering various high speed multiple applications of Internet of Things (IoT) regarding wireless standards S-band WLAN (WiFi, Bluetooth, Z-wave, wireless HART, WBAN), Lower C-band (WAIC, satellite communication transmission application), C-band WLAN, X-band (ITU region 2), Ku-band (Direct broadcast satellite system, Terrestrial microwave communication system service) and K band (Radar communication application) with S 11 ≤ -10 dB. The radiation characteristics (gain/efficiency/patterns/impedance matching) are shown in stable and improved form at achieved wireless modes.