bluuebunny/crossref_metadata_2025_split huggingface dataset:
Xenogenic Acellular Pericardium Matrix of Caprine and Porcine Origin for Abdominal Wall Reconstruction in Rabbits
Authors: Padhan A. , Nath P.J. , Sarma K.K. , Dutta B. , Nath R. , Deuri B. , Singh C.K. 
Published: November 2022

Background: The abdominal wall defects require urgent medical attention owing to the voluminous visceral content and uneven wound edges, which remains a clinical challenge for the surgeon. In the present study, xenogenic porcine and caprine acellular pericardium matrix was evaluated for surgical reconstruction of the induced abdominal wall in rabbits. Methods: All total eighteen adult rabbits were divided into three equal groups. The defects were corrected with acellular caprine and porcine pericardium matrix in Group A and B, respectively and Group C was kept as control. Various parameters viz clinical, gross evaluation of surgical wound, degree of adhesion and histopathological changes were evaluated as per standard methods. Result: Clinical parameters and gross changes of the surgical wound showed significant changes on the 3rd and 5th day in all the groups. TLC, Serum Alkaline Phosphatase and Total Protein showed significant variation in Group A and B on the 10th day. Macroscopic and histopathological evaluation of implanted mesh has shows better host tissue proliferation in both the groups. Acellular caprine and porcine pericardium can be good options as bio-mesh for the repair of the abdominal wall and the subject may be considered for in-depth studies and further research programs.
Harmonising regulatory information on wine protected designation of origin in Europe
Authors: Candiago Sebastian , Tscholl Simon , Bassani Leonardo , Fraga Helder , Egarter Vigl Lukas 
Published: November 2022

Wine Protected Designation of Origin (PDO) products are strictly regulated and therefore highly susceptible to changes in climatic, environmental and socioeconomic conditions. Analysing the impacts of such changes has so far been challenging, because the legal specifications of wine PDOs in Europe have never been summarised in a harmonised dataset. Here, we present how we created the first inventory of regulatory information for the 1177 wine PDO in Europe, based on the geographical indication register of the European Union.
The Research Comparison Between the Consonants of Bahasa Indonesia and Chinese Mandarin
Authors: Hasel Clarosa Amanda 
Published: November 2022

Indonesian Students face a lot of difficulties when learning Chinese Mandarin, it is very common that them to mispronounce the consonants of Chinese Mandarin. There are not a lot of Indonesian Students who can pronounce Chinese Mandarin consonants accurately. Phonetics teaching is a very important part of learning other languages. Bahasa Indonesia is classified as “The Family of Austronesian Language”, and Chinese Mandarin is classified as Sino-Tibetan Language System. Although they have a different language systems, the two languages have a lot of similarities and differences in every aspect of it. If we look at the consonants of Bahasa Indonesia and Chinese Mandarin, Bahasa Indonesia has 23 consonants, and Chinese Mandarin has 22 consonants. These 2 kinds of languages have similarities and different points of the pronunciation and pronunciation methods.
Degradability of Rumen-Protected Soybean Meal with Different Temperatures and Heating Times in Bali Cattle
Authors: Wulandari Wulandari , Aldis Rinanti Eka , Ramadhan Dananto , Wulanningtyas Wulanningtyas , Astuti Andriyani , Adiarto Adiarto , Yusiati Lies Mira , Noviandi Cuk Tri , Widyobroto Budi Prasetyo , Agus Ali 
Published: November 2022

The goal of this study was to ascertain the impact of soybean meal's temperature and heating duration as undegraded protein (UDP) on Bali cattle's dry matter (DM) and organic matter (OM) degradation kinetics. Soybean meal is a feed ingredient with high protein content, which is about 48%, and is rapidly degraded in the rumen. In this investigation, a factorial design was employed with the first factor being temperature (60, 80, 100, and 120°C), and the second factor being heating time (10, 20, 30, and 40 min). Protected soybean meal was tested for degradation using the in sacco technique on the rumen of fistulous Bali cattle. A sample of 5.0 g was put into a nylon bag and then for 0, 2, 4, 8, 16, 24, and 48 h in the rumen, then analyzed for feed residues for DM and OM. The results showed that soybean meal protected by the heating method could reduce the degradation of DM and OM in the rumen (p<0.05). Heating at 120°C for 40 min showed the lowest DM and OM degradations in this study.
Current Tectonic Stress State in an Iron Mine District, North China, Based on Overcoring, Hydraulic Fracturing, and Acoustic Emission Stress Measurements
Authors: Li Peng , Sun Jinglai , Cai Meifeng , Miao Shengjun , Guo Qifeng , Ren Fenhua , Wu Xu 
Published: November 2022

Abstract
Full knowledge of the current tectonic stress state is crucial for assessing open-pit mine slope stability and regional tectonic evolution and geodynamic processes. Overcoring, hydraulic fracturing, and acoustic emission in situ stress measurement techniques were adopted to determine the 3D stress tensor in an iron mine district, North China, and 25 sets of stress data ranging from 56 to 490 m were measured. Accordingly, the current tectonic stress state and its relationship to regional geological tectonics were investigated. The results indicated that the stress condition seemed to favor thrust and strike-slip faulting, and the stress field was particularly controlled by the horizontal tectonic stress. A high horizontal tectonic stress considerably influenced the stability of high and steep slopes in this mine district, which requires great attention. The stress directions derived from different methods were almost similar, indicating a dominant NEE–SWW stress field direction or near-E–W direction, comparable to the direction revealed by focal mechanism solutions and other stress indicators around the mine district. According to geological structure analysis, the present-day stress field in this district generally inherited the third-stage tectonic stress field while partially retaining the characteristics of the second-stage tectonic stress field, which is the result of dynamic action and tectonic movement during different geological periods, and the maximum principal stress direction of the tectonic stress field that affects the modern tectonic activity in this area is the NEE–EW direction.
Non-convex Quadratic Programming Using Coherent Optical Networks
Authors: Ronagh Pooya , Khosravi Farhad , Yildiz Ugur , Scherer Artur 
Published: November 2022

Abstract
We investigate the possibility of solving continuous non-convex optimization problems using a network of interacting quantum optical oscillators. We propose a native encoding of continuous variables in analog signals associated with the quadrature operators of a set of quantum optical modes. Optical coupling of the modes and noise introduced by vacuum fluctuations from external reservoirs or by weak measurements of the modes are used to optically simulate a diffusion process on a set of continuous random variables. The process is run sufficiently long for it to relax into the steady state of an energy potential defined on a continuous domain. As a first demonstration, we numerically benchmark solving box-constrained quadratic programming (BoxQP) problems using these settings. We consider delay-line and measurement-feedback variants of the experiment. Our benchmarking results demonstrate that in both cases the optical network is capable of solving BoxQP problems over three orders of magnitude faster than a state-of-the-art classical heuristic.
Management of ground tire rubber waste by incorporation into polyurethane-based composite foams
Authors: Hejna Aleksander , Kosmela Paulina , Olszewski Adam , Zedler Łukasz , Formela Krzysztof , Skórczewska Katarzyna , Piasecki Adam , Marć Mariusz , Barczewski Roman , Barczewski Mateusz 
Published: November 2022

Abstract
Rapid economic growth implicated the developing multiple industry sectors, including the automotive branch, increasing waste generation since recycling and utilization methods have not been established simultaneously. A very severe threat is the generation of enormous amounts of post-consumer tires considered burdensome waste, e.g., due to the substantial emissions of volatile organic compounds (VOCs). Therefore, it is essential to develop novel, environmentally friendly methods for their utilization, which would hinder their environmental impacts. One of the most promising approaches is shredding, resulting in the generation of ground tire rubber (GTR), which can be introduced into polymeric materials as filler. The presented work is related to the thermomechanical treatment of GTR in a twin-screw extruder with zinc borate, whose incorporation is aimed to enhance shear forces within the extruder barrel. Modified GTR was introduced into flexible polyurethane (PU) foams, and the impact of modification parameters on the cellular structure, static and dynamic mechanical performance, thermal stability, as well as thermal insulation, and acoustic properties were investigated. Emissions of VOCs from applied fillers and prepared composites were monitored and evaluated. Depending on the treatment parameters, beneficial changes in foams’ cellular structure were noted, which enhanced their thermal insulation performance, mechanical strength, and thermal stability. It was proven that the proposed method of GTR thermomechanical treatment assisted by zinc borate particles might benefit the performance of flexible PU foamed composites and hinder VOCs emissions, which could broaden the application range of GTR and provide novel ways for its efficient utilization.
Non-Line-of-Sight Passive Acoustic Localization Around Corners
Authors: Boger-Lombard Jeremy , Slobodkin Yevgeny , Katz Ori 
Published: November 2022

Abstract
Non-line-of-sight (NLoS) imaging is an important challenge in many fields ranging from autonomous vehicles and smart cities to defense applications. Several recent works in optics and acoustics tackle the challenge of imaging targets hidden from view (e.g. placed around a corner) by measuring time-of-flight (ToF) information using active SONAR/LiDAR techniques, effectively mapping the Green functions (impulse responses) from several sources to an array of detectors. Here, leveraging passive correlations-based imaging techniques, we study the possibility of acoustic NLoS target localization around a corner without the use of controlled active sources. We demonstrate localization and tracking of a human subject hidden around the corner in a reverberating room, using Green functions retrieved from correlations of broadband noise in multiple detectors. Our results demonstrate that the controlled active sources can be replaced by passive detectors as long as a sufficiently broadband noise is present in the scene.
Non-invasive disruption of the blood-brain barrier in the marmoset monkey
Authors: Szuzupak Diego , Choi Sang-Ho , Alikaya Aydin , Mou Yongshan , Silva Afonso , Schaeffer David 
Published: November 2022

Abstract
The common marmoset monkey (Callithrix jacchus) is a species of rising prominence in the neurosciences due to their small size, ease of handling, fast breeding, and their shared functional and structural brain characteristics with Old World primates. With increasing attention on modeling human brain diseases in marmosets, understanding how to deliver therapeutic or neurotropic agents to the marmoset brain non-invasively is of great preclinical importance. In other species, including humans, transcranial focused ultrasound (tFUS) aided by intravenously injected microbubbles has proven to be a transient, reliable, and safe method for disrupting the blood-brain barrier (BBB), allowing for the focal passage of therapeutic agents that do not otherwise readily traverse the tight endothelial junctions of the BBB. The critical gap that we address here is to document parameters to disrupt the BBB reliably and safely in marmosets using tFUS. By integrating our marmoset brain atlases and the use of a marmoset-specific stereotactic targeting system, we conducted a series of systematic transcranial sonication experiments in nine marmosets. We demonstrate the effects of center frequency, acoustic pressure, burst period and duration, establish a minimum microbubble dose, estimate microbubble clearance time, and estimate the duration that the BBB remained open to passage. Successful BBB disruption was reported in vivo with MRI-based contrast agents, as well as Evans blue staining assessed ex vivo. Histology (Hematoxylin and Eosin staining) and immunohistochemistry indicated that the BBB can be safely and reliably opened with the parameters derived from these experiments.
Insecticidal and repellent activities of Cananga odorata leaf essential oil (Lam.) Hook. F. &amp; Thomson against a post-harvest pest of rice: Sitotroga cerealella Olivier
Authors: Elvis Adjalian , SESSOU Philippe , Alain Alitonou Guy , Franck Michels , Félicien Avlessi , Marie-Laure Fauconnier , Dansou Kossou , Sohounhloue Dominique 
Published: November 2022

Abstract
Today the use of plant extracts, in particular essential oils, is a natural alternative to synthetic insecticides in the fight against crop pests. The purpose of this research is to determine the chemical composition of the ylang-ylang Cananga odorata (Lam.) Hook. F. & Thomson leave essential oil and to evaluate on the one hand its ovicidal, larvicidal, insecticidal, anti-oviposition and insect repellent properties, and on the other hand its effectiveness in preserving the weight of the grains and the germination power of rice seeds against the Angoumois grain moth Sitotroga cerealella O., a major pest of rice in Benin. The essential oil from the leaves of the C. odorata (Lam.) Hook. F. & Thomson was obtained by hydro-distillation, and analysed by gas chromatography-mass spectrometry (GC-MS). The analysis showed that the oil contains 32 main compounds, the major ones being α-pinene (7.01%), lavandulyl acetate (7.19%), caryophyllene (30.33%), α-humulene (13.42%) and germacrene D (8.99%). Based on the findings of fumigation bioassays, the Cananga odorata (Lam.) Hook. F. & Thomson essential oil showed high toxicity against adult of the S. cerealella with values CL50 of 0.094μl/mL and CL90 of 0.46μl/mL. Similarly, our work has demonstrated that this oil has ovicidal and larvicidal or egg development retardant properties. It also caused strong oviposition inhibition activity of more than 97% in female of the S. cerealella O. and subsequently developed very good repellent or deterrent properties, with an average repellence rate of 75.7% against the S. cerealella O. insect. These insecticidal effects preserved grain weight, with weight losses of at most 0.38% and a paddy rice seed germination rate of more than 80% at the lowest applied dose of 0.2µL/mL.The essential oil from the leaves of the C. odorata (Lam.) Hook. F. & Thomson can be used as an alternative to modern toxic synthetic chemicals, for protection against this important pest of grains in storage in Benin.
CLINICAL LEARNING EXPERIENCES OF NURSING DEGREE STUDENTS AT THE PUBLIC TRAINING HOSPITALS: KHOMAS REGION, NAMIBIA
Authors: Kadhila Joseph Galukeni , Pretorius Louise 
Published: November 2022

AbstractIntroduction: Clinical placement provides an opportunity for socialization of students into the health system, and to acquire practice clinical skills in a real life setting while observing the deliverance of care by others. Despite the obvious benefits of clinical placements for students, poor relationships with the supervising nurse, environments that fail to promote belongingness and a lack of supervision hinders learning in the clinical setting. The purpose of the study was to assess the clinical learning experiences of the nursing degree students in general wards at the public training hospitals in Khomas Region.Aims: of the study were to explore and describe the clinical learning experiences by nursing degree students in general wards at the public training hospitals Khomas. The study aimed at answering the following central question:Tell me about your clinical learning experiences during your placement in general nursing wards of the two training hospitals in the Khomas region?Methods: In this study, the researcher selected a qualitative, explorative, descriptive and contextual design and 51 participants from the undergraduate second years, third years and fourth years were recruited. The data collection included 11-individual face to face interviews and the 8 Focus Group Discussions using semi structured interviews. Data was manually coded and analyzed using the Tesch’s method of data analyzes.Results: Four themes emerged from the exploration and description of nursing students clinical learning experiences. These were non-conducive learning environment, negative staff attitude, communication as barrier and shortage of staff. The results show that there were indeed constraints to learning in the clinical setting across all the years of study.Conclusion: Recommendations were made to the School of Nursing, the training hospitals and the Ministry of Health and Social services. Further research is needed on the clinical learning experiences of nursing students in other regions, and the lecturer’s experiences on clinical accompaniments. Hence, this study assessed clinical learning experiences of nursing degree students at the public training hospitals: Khomas region, Namibia.
Re-hospitalizations within 30-days and Mortality Outcomes Among Severely Visually Impaired and Blind Patients: Analysis of the National Readmission Database
Authors: Fatuyi Michael , Anibire Oladipupo , Harris Ché Matthew 
Published: November 2022

Abstract
Background
Readmissions among patients with severe vision impairment or blindness (SVI/B) has not been fully studied. We investigated hospital outcomes for adults with SVI/B in the United States.
Methods
Using the Nationwide Readmission Database year 2017, we analyzed primary outcomes for thirty-day readmission rates for patients with and without SVI/B. Secondary outcomes were in-hospital mortality rates for readmitted patients, in-hospital mortality rates for index patients, the five most common principal diagnoses for readmission, and resource utilization.
Results
34,558 patients had an index admission for SVI/B vs 24,600,000 who did not. Patients with SVI/B had a 13.3% [4,383] readmission rate within 30-days compared to 8.4% [2,033,329] without SVI/B. Compared to readmitted patients without SVI/B patients, those with SVI/B were older (mean [SD] age: 64.4 [SD ± 19] vs. 61.4 [SD ± 20] years) and had more comorbidities (Charlson comorbidity score ≥ 3: 79.2% [ 3,471] vs 60.9% [1,238,299]). The mortality rate among patients readmitted with SVI/B was 5.38% [236] vs 4.02% [81,740] for patients without SVI/B, p-value = 0.016. Top reasons for readmissions among patients with SVI/B included sepsis 12% [526], heart failure 10.5% [460)], acute renal failure 4.4% [193], complications due to type II diabetes mellitus 4.1% [178], and pneumonia 2.7% [118]. Mean length of stay for readmitted patients with SVI/B was 6.3 days (confidence interval [CI]: 6.0-6.7 days), vs 5.6 days for patients without SVI/B (CI: 5.5–5.8 days), p-value < 0.01. The mean hospital charges for readmitted patients with SVI/B was $57,202 (CI: $53,712–$61,292) vs $51,582 (CI: $49,966–$53,198), p-value < 0.01.
Conclusion
Patients with SVI/B had higher readmission rates, and greater mortality on readmissions compared to those without SVI/B. Interventional studies for optimal discharge strategies are critically needed to improve clinical and resource utilization outcomes in patients with SVI/B.
Predicting metastasis in Gastric cancer patients: machine learning-based approaches
Authors: Talebi Atefeh , Celis-Morales Carlos A , Borumandnia Nasrin , Abbasi Somayeh , Pourhoseingholi Mohamad Amin , Akbari Abolfazl , Yousefi Javad 
Published: November 2022

Abstract
Background
Gastric cancer (GC), with a 5-year survival rate of less than 40%, is known as the fourth principal reason of cancer-related mortality over the world. The study aimed to perform machine learning (ML) methods in GC patients.
Methods
The data applied in this study including 733 of GC patients diagnosed at Taleghani hospital. In order to predict metastasis in GC, machine learning approaches, including Naive Bayes (NB), Random Forest (RF), Support Vector Machine (SVM), Neural Network (NN), Regression Tree (RT) and Logistic Regression (LR), with 5-fold cross validation were performed. To assess the model performance, precision, sensitivity, specificity and AUC of Receiver operating characteristic (ROC) curve were obtained.
Results
262 (36%) experienced metastasis among 733 patients with GC. The RF of ML-based models, with size of tomur and age as two essential variables, is considered as efficient model, because of higher specificity and AUC (84% and 87%). Also, the sensitivity in SVM model seems to be better (93%).
Conclusion
According to AUC, sensitivity and specificity, both RF and SVM can be regarded as better ML-based algorithms among six applied ML-based methods.
Immunological correlates of protection following vaccination with glucan particles containing Cryptococcus neoformans chitin deacetylases
Authors: Levitz Stuart , Wang Ruiying , Oliveira Lorena , Lourenco Diana , Gomez Christina , Lee Chrono , Hester Maureen , Mou Zhongming , Ostroff Gary , Specht Charles 
Published: November 2022

Abstract
Vaccination with glucan particles (GP) containing the Cryptococcus neoformans chitin deacetylases Cda1 and Cda2 protect mice against experimental cryptococcosis. Here, immunological correlates of vaccine-mediated protection were explored. Studies comparing knockout and wild-type mice demonstrated CD4+ T cells are crucial, while B cells and CD8+ T cells are dispensable. Protection was abolished following CD4+ T cell depletion during either vaccination or infection, but was retained if CD4+ T cells were only partially depleted. Vaccination elicited systemic and durable antigen-specific immune responses in PBMCs, spleen and lungs. Following vaccination and fungal challenge, robust Th1 and Th17 responses were observed in the lungs. Protection was abrogated in mice congenitally deficient in IFNɣ, IFNɣ receptor, IL-1β, IL-6, or IL-23. Thus, CD4+ T cells and specific pro-inflammatory cytokines are required for GP-vaccine mediated protection. Importantly, retention of protection in the setting of partial CD4+ T depletion suggests a pathway for vaccinating at-risk immunocompromised individuals.
3D Single Shot Lensless Incoherent Optical Imaging Using Coded Phase Aperture System with Point Response of Scattered Airy Beams
Authors: Kumar Ravi , Anand Vijayakumar , Rosen Joseph 
Published: November 2022

Abstract
Interferenceless coded aperture correlation holography (I-COACH) techniques have been revolutionizing the field of incoherent imaging, offering multidimensional imaging capabilities with a high temporal resolution in a simple optical configuration and at a low cost. The I-COACH method uses optical modulators (OMs) between the object and the image sensor, which encodes the 3D location information of a point into a unique spatial intensity distribution. The system usually requires a one-time calibration procedure in which the point spread functions (PSFs) at different depths and or wavelengths are recorded. When an object is recorded under identical conditions, the multidimensional image of the object is reconstructed by processing the object intensity with the PSFs. In the previous versions of I-COACH, the OM mapped every object point to a scattered intensity distribution or random dot array pattern. In this study, I-COACH has been realized using an OM that maps every object point into a sparse random array of Airy beams. The phase-only mask displayed on the OM was designed by random phase multiplexing of Airy beam generators. The simulation and experimental results obtained for the proposed method are significantly better than the previous versions of I-COACH.