bluuebunny/crossref_metadata_2025_split huggingface dataset:
Musculoskeletal and neurological manifestations in a cohort of Egyptian Familial Mediterranean fever patients: genotype-phenotype correlation
Authors: Ahmed Mohamed H. , Ibrahim Amira M. , Ragab Salma M. , Mahros Ayah M. 
Published: February 2022

Abstract
Background
Familial Mediterranean Fever (FMF) is a periodic auto-inflammatory disease with multiple systemic manifestations. This study aims to describe the various musculoskeletal and neurological manifestations in a cohort of Egyptian FMF patients and to evaluate their relation to the different Mediterranean fever gene (MEFV) mutations.

Results
This study involved 145 FMF patients, of them 62.1% were females and 31.7% were of the pediatric age. All involved patients had homozygous MEFV gene mutation. The presenting manifestation in 71.9% of these patients was abdominal pain followed by musculoskeletal manifestations in 35.2% of them. 38.6 % of the involved patients had arthritis during the period of follow-up. Monoarthritis was the most frequent pattern of arthritis. Arthralgia was present in 96.6% of the studied patients. Myalgia was present in 19.3% of the studied patients especially involving the lower limb muscles with one case of protracted febrile myalgia. Neurological manifestations were present in about 86.9 % of patients with vertigo, paresthesia, and seizures as the most common. Five major MEFV gene mutations were found in most of the studied patients (135 patients): M694V, M680I, E148Q, V726A, and M694I. When a comparative study was done between these five major mutations according to the age of onset of the symptoms, different musculoskeletal and neurological manifestations, ESR, serum amyloid level and dose of colchicine, no statistical difference was found.

Conclusion
Musculoskeletal manifestation is the second most common presenting symptom in a cohort of Egyptian FMF patients after abdominal pain. Arthralgia is the most frequent musculoskeletal manifestation while monoarthritis of the knee or ankle joint is the most common pattern of arthritis in FMF patients. Vertigo, paresthesia, and seizures are the most frequent neurological manifestations. Musculoskeletal manifestations, neurological manifestations, serum amyloid level, and dose of colchicine are not related to the type of the genetic mutation in this cohort.
A General Branch-and-Cut Framework for Rotating Workforce Scheduling
Authors: Becker Tristan , Schiffer Maximilian , Walther Grit 
Published: February 2022

In this paper, we propose a general algorithmic framework for rotating workforce scheduling. We develop a graph representation that allows to model a schedule as a Eulerian cycle of stints, which we then use to derive a problem formulation that is compact toward the number of employees. We develop a general branch-and-cut framework that solves rotating workforce scheduling in its basic variant, as well as several additional problem variants that are relevant in practice. These variants comprise, among others, objectives for the maximization of free weekends and the minimization of employees. Our computational studies show that the developed framework constitutes a new state of the art for rotating workforce scheduling. For the first time, we solve all 6,000 instances of the status quo benchmark for rotating workforce scheduling to optimality with an average computational time of 0.07 seconds and a maximum computational time of 2.53 seconds. These results reduce average computational times by more than 99% compared with existing methods. Our algorithmic framework shows consistent computational performance, which is robust across all studied problem variants. Summary of Contribution: This paper proposes a novel exact algorithmic framework for the well-known rotating workforce scheduling problem (RWSP). Although the RWSP has been extensively studied in different problem variants and for different exact and heuristic solution approaches, the presented algorithmic framework constitutes a new state-of-the-art for the RWSP that solves all known benchmark sets to optimality and improves on the current state-of-the-art by orders of magnitude with respect to computational times, especially for large-scale instances. The paper is both of methodological value for researchers and of high interest for practitioners. For researchers, the presented framework is amenable for various problem variants and provides a common ground for further studies and research. For practitioners and software developers, low computational times of a few seconds allows the framework to be to embedded into personnel scheduling software.
Knowledge of health rights and community participation in primary care
Authors: Agegnehu Wubetu , Derese Msganaw , Genetu Amare , Hailemariam Shewangizaw 
Published: February 2022

Background/Aims Primary care providers are encouraged to promote community participation in care, so that patients are engaged in health priorities and solutions. This study assessed the level of knowledge regarding health rights and community participation in a town in Mizan-Aman, Ethiopia. Methods A community-based cross-sectional study design was used. A structured questionnaire was administered to 374 community health leaders assessing their knowledge of health rights and the level of community participation in primary care, according to five indicators: leadership, organisation, management, resource mobilisation and needs assessment. Results A total of 326 out of 374 questionnaires were returned. The majority (n=205, 62.9%) had limited knowledge of health rights, while 189 (58%) indicated poor community participation in primary healthcare. There was no significant association between knowledge of health rights and level of community participation. Conclusions Knowledge of health rights is generally lacking in these communities, as is public participation in primary care service planning. A community-based health education programme is needed to raise awareness of patient rights and enhance community participation in primary care.
Acute onset low back pain leading to a diagnosis of cauda equina syndrome: a case study
Authors: Read Haley , Mortimore Gerri 
Published: February 2022

Cauda equina syndrome is rarely seen in primary care, but advanced practitioners must be aware of the possibility. Haley Read and Gerri Mortimore highlight a case study leading to a diagnosis of the condition One of the most common symptoms managed in primary care is lower back pain, which affects approximately 20% of the UK population at any one time ( National Collaborating Centre for Primary Care, 2009 ). There are many differential diagnoses for the cause of back pain, with one such potential diagnosis being cauda equina syndrome. In this instance, it is of paramount importance that the correct diagnosis is reached quickly with urgent referral into secondary care for the instigation of treatment to prevent paralysis. This case review will examine a patient presenting to primary care with lower back pain and diagnosed with cauda equina syndrome.
Downlink communication experiments with OSIRISv1 laser terminal onboard Flying Laptop satellite
Authors: Giggenbach Dirk , Fuchs Christian , Schmidt Christopher , Rödiger Benjamin , Gaißer Steffen , Klinkner Sabine , Phung Duy-Ha , Chabé Julien , Courde Clément , Maurice Nicolas , Mariey Hervé , Samain Etienne , Artaud Géraldine 
Published: February 2022

Downlink measurement campaigns from the optical downlink terminal OSIRISv1 onboard the LEO satellite Flying Laptop were carried out with the French Observatoire de la Côte d’Azur and with two Optical Ground Stations of the German Aerospace Center. On/off keyed data at 39 Mb/s were modulated on the laser signal, and according telecom reception was performed by the ground stations. The pointing of the laser terminal was achieved by open-loop body pointing of the satellite orientation, with its star sensor as attitude control signal. We report here on the measurements and investigations of the downlink signal and the data transmission.
Regulation on Genetically Modified Animals: Proposed and Its Possible Application in Indonesia
Authors: Tiesnamurti Bess , Muharsini Sri , Shiddieqy M I 
Published: February 2022

The government is responsible for fulfil the needs of safe, healthy and halal food for all its people in a sustainable manner. The world population will increase from 7 to 9 billion people in 2050. While the availability of land may not increase in the future, it may even not be used for agriculture. Scientists are trying to overcome this problem by creating technologies that can increase livestock productivity, one of which is through a genetically modified process. Genetically modified animals are animals that have been genetically modified for many purposes including yields and disease resistance. Although genetically modified animals are at the last stage of research and the possibility to entering Indonesia remains small, but government should prepare a regulation related to it. European countries and USA have regulations to control genetically modified animals. Malaysia also has applied a similar regulation since 2007. Currently, Indonesia has formed an authority that oversees the genetically modified product, namely Biosafety Commission (<em>Komisi Keamanan Hayati</em>) on genetically modified products. However, this commission only supervises genetically modified organism in food and feed. This paper is aimed to propose the regulation for genetically modified animal that may be entering Indonesia and or be researched by Indonesian scientists.
Historiografia e Negação do Holocausto: o caso Lipstadt vs. Irving
Authors: Soares de Brito Wallace Guilherme 
Published: February 2022

Este trabalho tem como objetivo elaborar uma interface entre filosofia e cinema a partir de uma análise temática do filme "Negação" (2016) sob o viés do verbete Filosofia da História de Daniel Little (2016); o que faremos através de uma síntese da trama que envolve dois escritores: a professora Deborah Lipstadt, historiadora; e David Irving, autor negacionista do Holocausto. Utilizaremos como fontes a obra Negação, da Professora Lipstadt, bem como o bestseller Hitler’s War (1977), do Irving. Focaremos nos argumentos apresentados por Irving, quais sejam: Hitler não sabia da “Solução Final”, e quando soube tentou evitá-la; nenhuma pessoa foi executada nos campos de extermínio nazistas e, por fim, o que conhecemos como Holocausto não aconteceu. Os compararemos com três conceitos desenvolvidos por Little (2016) em seu verbete mencionado: o papel do historiador, os critérios de verificação que atestam suas "verdades" e a possibilidade de neutralidade na pesquisa, analisando o filme à luz da obra de ambos os autores. Concluímos que Irving se distancia do viés História da Filosofia e que sua argumentação é baseada em deturpações de documentos históricos, especulações infundadas e sua vontade pessoal de que fosse verdade.
Palavras-chave: Historiografia, Negação do Holocausto, Antissemitismo.

Historiography and Holocaust Denial: The Case Lipstadt vs. Irving

Abstract: This work aims to elaborate an interface between historiography and cinematography based on a thematic analysis of the film "Negação" (2016) under the bias of the entry Philosophy of History by Daniel Little (2016); what we will do through a synthesis of the plot that involves two writers: professor Deborah Lipstadt, historian; and David Irving, author and Holocaust denialist. We will use as sources the book Negação (2017), by Professor Lipstadt, as well as the bestseller Hitler’s War (1977), by Irving. We will focus on the arguments presented by Irving, namely: Hitler did not know about the “Final Solution”, and when he did he tried to avoid it; no one was executed in the Nazi death camps and, finally, what we know as the Holocaust did not happen. We will compare them with three concepts developed by Little (2016) in his mentioned entry: the role of the historian, the verification criteria that attest to his "truths" and the possibility of neutrality in the research, analyzing the film in the light of the work of both authors . We conclude that Irving distances himself from the History of Philosophy bias and that his argument is based on misrepresentations of historical documents, unfounded speculations and his personal desire for it to be true.
Keywords: Historiography, Holocaust Denial, Antisemitism.
O Que Parece Melhor
Authors: Becker Silvério 
Published: February 2022

The Greatest Apparent Good (O Que Parece Melhor) é o quinto capítulo da obra Doctrine of the Will, publicada originalmente em 1845. Cf. MAHAN, Asa. Doctrine of the Will: R. E. Gillet. Oberlin, 1845. Disponível, em 23/04/2021, em Doctrine of the Will (gutenberg.org). Para a presente tradução, o texto utilizado foi: The Greatest Apparent Good. In: MAHAN, Asa. Doctrine of the Will. J. M. FITCH. Oberlin, 1847; pp 99-118. Disponível em 23/04/2021, em: Doctrine of the Will - Asa Mahan - Google Livros. O texto é de domínio público.
A filosofia na primeira universidade da América Latina (Universidad de San Marcos 1551)
Authors: Culleton Alfredo 
Published: February 2022

A filosofia na primeira universidade da América Latina (Universidad de San Marcos 1551)
Resumo: O artigo se propõe trazer a público um momento fundante da história da Filosofia nas Américas a partir do estudo da historia das Universidades e em especial a decana Universidad de San Marcos (1551), a sua fundação, funcionamento e legado. Neste contexto pretende igualmente apresentar dois notáveis intelectuais nativos que respiram o ar dessa universidade nas primeiras décadas: Jerónimo Valera e Juan de Espinosa Medrano.
Palavras-chave: Escolástica Ibero-americana; São Marcos; Universidades; Filosofia latinoamericana.
Philosophy at Latin America's First University (Universidad de San Marcos 1551)
Abstract: The article aims to bring to the public a foundational moment in the history of Philosophy in the Americas, based on the study of the history of Universities and, in particular, the dean Universidad de San Marcos (1551), its foundation, functioning and legacy. In this context, it also intends to present two notable native intellectuals who lived the atmosphere of that university in those first decades: Jerónimo Valera and Juan de Espinosa Medrano.
Key words: Ibero-American Scholasticism; San Marcos; Universities; Latin American philosophy.
Filosofía en la Primera Universidad de América Latina (Universidad de San Marcos 1551)
Resumen: El artículo se propone acercar al público un momento fundacional de la historia de la Filosofía en América a partir del estudio de la historia de las Universidades y en particular de la decana Universidad de San Marcos (1551), su fundación, funcionamiento y legado. En ese contexto, también pretende presentar a dos destacados intelectuales nativos que respiran el aire de esa universidad en las primeras décadas: Jerónimo Valera y Juan de Espinosa Medrano.
Palabras clave: escolástica iberoamericana; San Marcos; universidades; filosofía latinoamericana.
Data de registro: 16/09/2021
Data de aceite: 20/12/2021
A filosofia na Pedagogia do Oprimido
Authors: Sobral Santos João Wilson 
Published: February 2022

A filosofia na Pedagogia do Oprimido
Resumo: O artigo pretende realizar uma aproximação introdutória da filosofia presente na obra Pedagogia do Oprimido (1968) de Paulo Freire. Seguindo o fluxo original da obra em quatro seções, analisa-se como conceitos criados ou utilizados por Freire correspondem a ou dialogam com conceitos de algumas correntes filosóficas, sobretudo, a fenomenologia, o existencialismo, a dialética hegeliana e o pensamento marxiano e marxista em geral. Entre outros temas, também são abordados o cristianismo crítico de Freire, a legitimidade da violência do oprimido, a aderência do oprimido ao opressor (passando rapidamente por alguns conceitos psicanalíticos), a catarse da metodologia. Destaca-se ainda a forte influência sobre Freire exercida pelo filósofo brasileiro Álvaro Vieira Pinto.
Palavras-chave: pedagogia do oprimido; dialética; fenomenologia; marxismo.

Philosophy in Pedagogy of the Opressed
Abstract: The article intends to carry out an introductory approach to the philosophy present in the work Pedagogy of the Oppressed (1968) by Paulo Freire. Following its original flow in four sections, it is analyzed how concepts created or used by Freire correspond to or dialogue with concepts from several philosophical currents such as phenomenology, existentialism, Hegelian dialectics and Marxian and Marxist thought in general. Freire's critical Christianity, the legitimacy of the violence of the oppressed, the adherence of the oppressed to the oppressor (quickly passing through some psychoanalytic concepts) and the catharsis of methodology are also addressed topics. The strong influence of the Brazilian philosopher Álvaro Vieira Pinto on Freire is highlighted as well.
Key-words: pedagogy of the oppressed; dialectics; phenomenology; marxism.

La philosophie en Pédagogie des Opprimés
Résumé: L'article vise à réalizer une approche introductive à la philosophie présente dans l'ouvrage Pédagogie des opprimés (1968) de Paulo Freire. Suivant sa flux original en quatre sections, il est analysé comment les concepts créés ou utilisés par Freire correspondent ou dialoguent avec des concepts de certains courants philosophiques, surtout la phénoménologie, l'existentialisme, la dialectique hégélienne et la pensée marxienne et marxiste en général. Le christianisme critique de Freire, la légitimité de la violence de l'opprimé, l'adhésion de l'opprimé à l'oppresseur (en passant rapidement par quelques concepts psychanalytiques) et la catharsis de la méthodologie sont themes également abordés. Il est remarqué aussi la forte influence du philosophe brésilien Álvaro Vieira Pinto sur Freire.
Mots-clés: pédagogie des opprimés ; dialectique ; phénoménologie ; marxisme.

Data de registro: 25/09/2021
Data de aceite: 01/12/2021
Comparison of kriging and least-squares collocation – Revisited
Authors: Ligas Marcin 
Published: February 2022

Abstract
The well-known to physical geodesists method of least-squares collocation and the geostatistical method of kriging probably known to the broader audience are compared. Both methods are rooted in Wiener–Kolmogorov’s (W–K) prediction theory; but, since necessity is the mother of invention, the W–K foundations have been extended to satisfy the needs of particular applications. The paper presents a link or rather an equivalence of the two methods as far as their basic forms are considered (specialization to geodetic boundary-value problems, covariance propagation between functionals and nonlinear geostatistical methods are excluded from this comparison). Only scalar random fields (univariate case) and the assumption of a second-order structure of a random function are considered. Due to the equivalence of their basic formulas, both techniques share the same advantages and disadvantages. The paper also shows the difference as to the predicted values and prediction variances in case of exact and filtered (noise reduction) prediction models. This theoretical comparison of the methods has practical implications because of readily available geostatistical software that, in local as well as global applications, can be used for predictive problems occurring in geodesy and surveying.
On hyponormality on a weighted annulus
Authors: Sadraoui Houcine , Halouani Borhen , Garayev Mubariz T. 
Published: February 2022

Abstract
In this work, we consider the hyponormality of Toeplitz operators on the Bergman space of the annulus with a logarithmic weight. We give necessary conditions when the symbol is of the form

φ
+

ψ

¯

\varphi +\overline{\psi }

, where

φ

\varphi

and

ψ

\psi

are analytic on the annulus

{

z
∈
C
;

1

/

2
<
∣
z
∣
<
1

}

\{z\in {\mathbb{C}};\hspace{0.25em}1\hspace{-0.08em}\text{/}\hspace{-0.08em}2\lt | z| \lt 1\}

.
On a fractional Schrödinger-Poisson system with strong singularity
Authors: Yu Shengbin , Chen Jianqing 
Published: February 2022

Abstract
We investigate a fractional Schrödinger-Poisson system with strong singularity as follows:

(

−
Δ

)

s

u
+
V

(

x

)

u
+
λ
ϕ
u
=
f

(

x

)

u

−
γ

,

x
∈

R

3

,

(

−
Δ

)

t

ϕ
=

u

2

,

x
∈

R

3

,

u
>
0
,

x
∈

R

3

,

\left\{\begin{array}{ll}{\left(-\Delta )}^{s}u+V\left(x)u+\lambda \phi u=f\left(x){u}^{-\gamma },& x\in {{\mathbb{R}}}^{3},\\ {\left(-\Delta )}^{t}\phi ={u}^{2},& x\in {{\mathbb{R}}}^{3},\\ u\gt 0,& x\in {{\mathbb{R}}}^{3},\end{array}\right.

where

0
<
s
≤
t
<
1

0\lt s\le t\lt 1

with

4
s
+
2
t
>
3

4s+2t\gt 3

,

λ
>
0

\lambda \gt 0

and

γ
>
1

\gamma \gt 1

. When

V

V

and

f

f

satisfy certain conditions, existence and uniqueness of positive solution

u

λ

{u}_{\lambda }

are established via variational method and Nehari method. We also describe the asymptotic behaviour of

u

λ

{u}_{\lambda }

as

λ
→
0

\lambda \to 0

.
Sharp function estimates and boundedness for Toeplitz-type operators associated with general fractional integral operators
Authors: Chen Dazhao , Huang Hui 
Published: February 2022

Abstract
In this paper, we establish some sharp maximal function estimates for certain Toeplitz-type operators associated with some fractional integral operators with general kernel. As an application, we obtain the boundedness of the Toeplitz-type operators on the Lebesgue, Morrey and Triebel-Lizorkin spaces. The operators include the Littlewood-Paley operator, Marcinkiewicz operator and Bochner-Riesz operator.
Poly-falling factorial sequences and poly-rising factorial sequences
Authors: Kim Hye Kyung 
Published: February 2022

Abstract
In this paper, we introduce generalizations of rising factorials and falling factorials, respectively, and study their relations with the well-known Stirling numbers, Lah numbers, and so on. The first stage is to define poly-falling factorial sequences in terms of the polyexponential functions, reducing them to falling factorials if

k
=
1

k=1

, necessitating a demonstration of the relations: between poly-falling factorial sequences and the Stirling numbers of the first and second kind, respectively; between poly-falling factorial sequences and the poly-Bell polynomials; between poly-falling factorial sequences and the poly-Bernoulli numbers; between poly-falling factorial sequences and poly-Genocchi numbers; and recurrence formula of these sequences. The later part of the paper deals with poly-rising factorial sequences in terms of the polyexponential functions, reducing them to rising factorial if

k
=
1

k=1

. We study some relations: between poly-falling factorial sequences and poly-rising factorial sequences; between poly-rising factorial sequences and the Stirling numbers of the first kind and the power of

x

x

; and between poly-rising factorial sequences and Lah numbers and the poly-falling factorial sequences. We also derive recurrence formula of these sequences and reciprocal formula of the poly-falling factorial sequences.