bluuebunny/crossref_metadata_2025_split huggingface dataset:
Narcissism – the refusal of twoness through sexual addiction and pornography
Authors: Schwartz Susan E. 
Published: April 2022

AbstractProceeding from oneness to twoness is a psychological process of relating inter‐ and intrapersonally. This article links the perspectives of French psychoanalyst André Green’s concepts of the dead mother and narcissism with Hester Solomon, British Jungian analyst writing on the ‘as‐if’ personality. These concepts are elucidated with the composite example of a self‐described sexually addicted man. His behaviours attempted to mask the shadows of melancholy, a fragile self, and the absence of self‐animation from early emotional wounds. He did not know love or the other.André Green, French psychoanalyst, described feelings of misery, lack, and emptiness. The defence against relatedness arises from fears of replicating the original object losses. He delineated death narcissism and life narcissism as limiting relationships and creating the illusionary.Narcissus could not live if he knew himself. Immersion within singularity occludes relationship to the unconscious and the other, like Echo. Jung’s concept of the transcendent function evolves from inclusion of the symbolic through listening to the language of the unconscious. Through the transference and countertransference, the former disowned and split‐off others, secreted in the shadows of addictions, open relatedness to self, soul, and world.
Perspectivism and shamanism in the Jungian clinic: the jaguar as an archetypal image of the Latin American cultural unconscious
Authors: Teixeira de Menezes Ana Luisa , Boechat Walter 
Published: April 2022

AbstractAmerindians, living in a perspective of synchronicity, attribute to symmetry a negative value that produces an understanding of unstable dualism cosmologies, in a continuous and dynamic imbalance, in a notion of complementarity between conscious and unconscious. These notions are in line with the view of synchronicity proposed by Jung (1952/1972) and Cambray (2013), a view that expands temporal, acausal boundaries, within a perspective of interconnection, resonance and correspondence. Amerindian epistemologies break‐up the discontinuity between animals and humans. By establishing a parallel with the Jungian concept of the relationship between unconscious and conscious, we reach a dimension of personification of both, a continuous and permanent flow of meaning. We introduce the jaguar as a symbol of Amerindian cultures and as an archetypal image of the numinosum that activates the unconscious, in asymmetrical and symmetrical movements. This is a qualitative contribution of indigenous mythologies to the understanding of the relationship between unconscious and conscious. Through perspectivism and Amerindian shamanism, we reflect on the archetypal image of the jaguar, as a mythological Latin American knowledge, which contributes to an understanding of the human being in the world, in an instinctive and spiritual integration. Recognizing this cosmos expands the ability to observe and access another point of view, in which the human being is seen in the jaguar, a personification or psychification of his unconscious. In clinical practice, it means finding the humanity that was left behind by that human who became an animal. The shaman, as a therapist, takes on the role of an active interlocutor in the exchange of human and non‐human subjectivities, in an amplification process.
Whispering at the edges: engaging ephemeral phenomena
Authors: Winborn Mark 
Published: April 2022

AbstractThis paper conceptualizes the analyst’s capacity to recognize and engage ephemeral phenomena in the analytic setting as an essential pillar of deep analytic engagement. It proposes that the analyst’s capacity to engage the ephemeral is an ongoing developmental progression which complements and deepens the other areas of analytic knowledge acquired during analytic training such as theory, technique, archetypal patterns, psychopathology and development. The paper provides a working definition of the ephemeral and focuses on the phenomenological experience of the ephemeral. It also discusses the use of reverie in ephemeral engagement and the use of poetry to develop the analyst’s sensitivity and responsivity to ephemeral moments.
Production of chitin‐ and chitosan‐oligosaccharide using the edible insect, Tenebrio molitor
Authors: Song Yong‐Su , Jo Yong Hun , Han Yeon Soo , Jung Woo‐Jin 
Published: April 2022

AbstractEdible insects are not only good food ingredients for people, but also open the possibility of functional food and pharmaceutical raw materials. This study investigated the production of chitin‐oligosaccharide and chitosan‐oligosaccharide using edible insect, Tenebrio molitor (Tm). Chitin of Tm larvae was prepared using demineralization (2 N HCl, room temp., 3 h), deproteinization [5% NaOH (w/w) for 3.5 h at 70°C], and decolorization (3% H2O2 for 1.5 h at 80°C). Chitosan of Tm larvae was prepared by Tm chitin deacetylation at 50% NaOH (w/w) for 5 h at 105°C. The chitin of Tm yielded 50% chitosan, and the final extraction yield of chitin and chitosan from dried Tm larvae was 6.82% and 3.75%, respectively. Chitin‐oligosaccharide and chitosan‐oligosaccharide of Tm larvae were prepared via acid hydrolysis using 5.0 g of both Tm chitin and Tm chitosan. Finally, 2.12 g chitin‐oligosaccharide of Tm larvae was obtained through acid hydrolysis (con. HCl 100 mL for 4 h at 40°C). Chitosan‐oligosaccharide (2.5 g) of Tm larvae was produced via acid hydrolysis (con. HCl 50 mL for 1 h at 81°C) and purification. These results indicate that the industrial applicability of Tm chitin‐oligosaccharide and chitosan‐oligosaccharide is viable in the field of health supplements, as a large amount of these oligosaccharides can be obtained from edible insect, Tm larvae.
Effects of mandibular distraction osteogenesis on anesthetic implications in children with hemifacial microsomia
Authors: Xu Jin , Liu Wei , Deng Xiaoming , Yang Dong , Li Binghang , Chen Keyu 
Published: April 2022

AbstractBackgroundHemifacial microsomia (HFM) is a congenital craniofacial malformation, and its features include hypoplasia and asymmetry in skeletal tissue and soft tissue. These features are usually associated with a difficult airway. Mandibular distraction osteogenesis can achieve mandibular advancement, but its effect on the subsequent laryngoscopic views has not been adequately documented.AimThe aim of this study was to determine the change in laryngoscopic views after mandibular distraction osteogenesis (MDO) in children with HFM and to examine the radiological changes after MDO by using computed tomography (CT)‐based three‐dimensional (3‐D) airway reconstruction.MethodsAn observational prospective study was carried out in children with HFM undergoing MDO. All children underwent 3‐D airway reconstruction preoperatively before the placement and removal of the distractor. The temporomandibular joint lesions in children were classified by the Pruzansky–Kaban classification. The Cormack–Lehane grade was assessed after induction under direct laryngoscopy. The relationship between difficult laryngoscopy and the Pruzansky–Kaban classification was assessed. Changes in the upper pharyngeal airway parameters and laryngoscopic views were analyzed.ResultsForty children (ages ranging from 5 to 16 years, males = 26, females = 14) with HFM underwent 80 anesthesia for MDO. The incidence of difficult laryngoscopy before mandibular distraction was 5/12 (41.7%) in type IIa, 19/24 (79.2%) in type IIb and 1/4 (25%) in type III HFM. The mean difference in the incidence of difficult laryngoscopy before and after MDO was 33.3% (95% CI: −6.7% to 73.3%), 50.0% (95% CI: 8.4% to 91.6%), and 0% for type IIa, type IIb, and type III, respectively. In type IIb, 12/19 cases of difficult laryngoscopy became easy after mandibular distraction: this was associated with an increase in the palatopharyngeal and glossopharyngeal CT parameters (p < .05). In type IIa, 5/5 cases of difficult laryngoscopy became easy after mandibular distraction, and 1/7 cases of easy laryngoscopy became difficult laryngoscopy. However, there were no significant changes in the palatopharyngeal, glossopharyngeal, and hypopharyngeal CT parameters in type IIa and type III HFM (p > .05).ConclusionsMDO can improve the laryngoscopic views in children with HFM. According to the Pruzansky–Kaban classification, children with type IIb showed the highest incidence of difficult laryngoscopy before MDO. After MDO, the improvement in laryngoscopic views under direct laryngoscopy in type IIb was related to the increase in the palatopharyngeal and glossopharyngeal volume.
Scalability of the Positive and Negative Syndrome Scale in first‐episode schizophrenia assessed by Rasch models
Authors: Baandrup Lone , Allerup Peter , Nielsen Mette Ø. , Düring Signe W. , Bojesen Kirsten B. , Leucht Stefan , Galderisi Silvana , Mucci Armida , Bucci Paola , Arango Celso , Díaz‐Caneja Covadonga M. , Dazzan Paola , McGuire Philip , Demjaha Arsime , Ebdrup Bjørn H. , Fleischhacker Wolfgang W. , Kahn René S. , Glenthøj Birte Y. 
Published: April 2022

AbstractObjectiveHistorically, assessment of the psychometric properties of the Positive and Negative Syndrome Scale (PANSS) has had several foci: (1) calculation of reliability indexes, (2) extraction of subdimensions from the scale, and (3) assessment of the validity of the total score. In this study, we aimed to examine the scalability and to assess the clinical performance of the 30‐item PANSS total score as well as the scalability of a shorter version (PANSS‐6) of the scale.MethodsA composite data set of 1073 patients with first‐episode schizophrenia or schizophrenia spectrum disorder was subjected to Rasch analysis of PANSS data from baseline and 4–6 weeks follow‐up.ResultsThe central tests of fit of the Rasch model failed to satisfy the statistical requirements behind item homogeneity for the PANSS‐30 as well as the PANSS‐6 total score. For the PANSS‐30, Differential Item Functioning was pronounced both for the 7‐point Likert scale rating categories and when dichotomizing the rating categories. Subsequently, the Rasch structure analysis in the context of dichotomized items was used to isolate and estimate a systematic error because of item inhomogeneity, as well as a random error. The size of the combined sources of error for the PANSS‐30 total score approximated 20% which is often regarded as clinical cut‐off between response versus no‐response.ConclusionThe results demonstrate the operational consequences of a lack of statistical fit of the Rasch model and suggest that the calculated measure of uncertainty needs to be considered when using the PANSS‐30 total score.
Development of a co‐designed, evidence‐based, multi‐pronged strategy to support normal birth.
Authors: Allen Jyai , Toohill Jocelyn , Creedy Debra K. , Callander Emily J. , Gamble Jenny 
Published: April 2022

AbstractAustralia's caesarean section (CS) rate has been steadily increasing for decades. In response to this, we co‐designed an evidence‐based, multi‐pronged strategy to increase the normal birth rate in Queensland and reduce the need for CS. We conducted three workshops with a multi‐stakeholder group to identify a broad range of options to reduce CS, prioritise these options, and achieve consensus on a final strategy. The strategy comprised of: universal access to midwifery continuity‐of‐care and choice of place of birth; multi‐disciplinary normal birth education; resources to facilitate informed decision‐making; respectful maternity care and positive workplace culture; and establishment of a Normal Birth Collaborative.
Evolutionary adaptation highlights the interconnection of fatty acids, sunlight, inflammation and epithelial adhesion
Authors: Hlusko Leslea J. , McNelis Madeline G. 
Published: April 2022

AbstractGene variants that influence human biology today reflect thousands of years of evolution. Genetic effects on infant health are a major point of selective pressure, given that childhood survival is essential to evolutionary success. Knowledge of this evolutionary history can have implications for paediatric research.ConclusionAn episode of human adaptation to the extremely low ultraviolet radiation environment of the Arctic 20,000 years ago implicates the Ectodysplasin A Receptor (EDAR) and the Fatty Acid Desaturases (FADS) in human lactation and epithelial inflammation.
Estimation of the autosomal contribution to total additive genetic variability of carcass traits in Japanese Black cattle
Authors: Ogawa Shinichiro , Matsuda Hirokazu , Taniguchi Yukio , Watanabe Toshio , Sugimoto Yoshikazu , Iwaisaki Hiroaki 
Published: April 2022

AbstractWe attempted to estimate the additive genetic variance explained by each autosome, using genotype data of 33,657 single nucleotide polymorphism (SNP) markers in 2271 Japanese Black fattened steers. Traits were cold carcass weight, ribeye area, rib thickness, subcutaneous fat thickness, estimated yield percentage, and marbling score. Two mixed linear models were used: One is that (model 1) incorporating a genomic relationship matrix (G matrix) constructed by using all available SNPs, and another (model 2), incorporating two G matrices constructed by using the SNPs on one autosome and using those on the remaining autosomes. Genomic heritabilities estimated using model 1 were moderate to high. The sums of the proportions of the additive genetic variance explained by each autosome to the total genetic variance estimated by using model 2 were >90%. For carcass weight, the proportions explained by Bos taurus autosomes 6, 8, and 14 were higher than those explained by the remaining autosomes. In some cases, the estimated proportion was close to 0. The results obtained from model 2 could provide a novel insight into the genetic architecture, such as heritability per chromosome, of carcass traits in Japanese Black cattle, although further careful investigation would be required.
Pharmacokinetics of glucagon after intravenous, intraperitoneal and subcutaneous administration in a pig model
Authors: Teigen Ingrid Anna , Åm Marte Kierulf , Carlsen Sven Magnus , Christiansen Sverre Christian 
Published: April 2022

AbstractIntroductionThere is increasing scientific evidence to substantiate using low‐dose glucagon as a supplement to insulin therapy in artificial pancreata for diabetes mellitus type 1. The delivery of both these hormones intraperitoneally would mimic normal physiology. However, our knowledge of the pharmacological properties of glucagon after intraperitoneal administration is limited. This study compared the pharmacokinetics of glucagon after intraperitoneal, subcutaneous and intravenous administration and the pharmacodynamic effects of glucagon on glucose metabolism after intraperitoneal and subcutaneous administration in a pig model.Materials and methodsTwelve pigs were included. Glucagon was administered intraperitoneally, subcutaneously and intravenously in a randomised order. Arterial samples were collected every 2–10 min for 150 min to determine plasma glucagon and blood glucose concentrations.ResultsThe bioavailability of glucagon was significantly lower after intraperitoneal compared with subcutaneous administration with a median difference (95% confidence interval) of 13% (4–22). The effect of glucagon on glucose metabolism was equal after intraperitoneal and subcutaneous administration.ConclusionsIntraperitoneal glucagon administration resulted in lower systemic glucagon exposure than subcutaneous administration without loss of efficiency. We interpret this as evidence of a major first‐pass metabolism of glucagon in the liver.
Children's social representations of utopian societies
Authors: Jost John T. , Fenton André , Jost E. , Fenton Zora E. L. 
Published: April 2022

AbstractHow do children in the U.S. represent the ideal society? A scientific understanding of how children engage in utopian thinking—and how their ideas relate to cross‐cultural standards developed by the United Nations—is potentially useful for the development of social movements aimed at progressive social change. In this article we report the results of group projects created by 56 fifth‐grade students (27 boys, 29 girls) in New York City who were instructed to work together in small groups to represent their ideal society of the future. We found that themes of economic prosperity and cultural sensitivity, especially the need to promote social and economic equality and to prevent discrimination and prejudice, were central to children's conceptions of the good society. On several major issues, the utopian societies that were proposed dovetailed with the sustainability development goals identified by the United Nations, especially ‘Decent Work and Economic Growth’, ‘Reduced Inequality’, and ‘Peace, Justice, and Strong Institutions’. The children were acutely aware of the need for environmental protection and climate action but understandably lacked a clear sense of how to provide ‘Affordable and Clean Energy’ and ‘Clean Water and Sanitation’ in their ideal societies.
Threat and deprivation are associated with distinct aspects of cognition, emotional processing, and psychopathology in children and adolescents
Authors: Schäfer Julia Luiza , McLaughlin Katie A. , Manfro Gisele Gus , Pan Pedro , Rohde Luis Augusto , Miguel Eurípedes Constantino , Simioni André , Hoffmann Maurício Scopel , Salum Giovanni Abrahão 
Published: April 2022

AbstractExposure to childhood adversity has been consistently associated with poor developmental outcomes, but it is unclear whether these associations vary across different forms of adversity. We examined cross‐sectional and longitudinal associations between threat and deprivation with cognition, emotional processing, and psychopathology in a middle‐income country. The sample consisted of 2511 children and adolescents (6–17 years old) from the Brazilian High‐Risk Cohort for Mental Conditions. Parent reports on childhood adversity were used to construct adversity latent constructs. Psychopathology was measured by the Child Behavior Checklist (CBCL) to generate a measure of general psychopathology (the “p” factor). Executive function (EF) and attention orienting toward angry faces were assessed using cognitive tasks. All measures were acquired at two time‐points 3 years apart and associations were tested using general linear models. Higher levels of psychopathology were predicted by higher levels of threat cross‐sectionally and longitudinally, and by deprivation longitudinally. For EF, worse performance was associated only with deprivation at baseline and follow‐up. Finally, threat was associated with attention orienting towards angry faces cross‐sectionally, but neither form of adversity was associated with changes over time in attention bias. Our results suggest that threat and deprivation have differential associations with cognitive development and psychopathology. Exposure to adversity during childhood is a complex phenomenon with meaningful influences on child development. Because adversity can take many forms, dimensional models might help to disentangle the specific developmental correlates of different types of early experience. A video abstract of this article can be viewed at https://www.youtube.com/watch?v=uEU0L8exyTM.
Severe iatrogenic hypoglycaemia modulates the fibroblast growth factor protein response
Authors: Nandakumar Manjula , Moin Abu Saleh Md , Ramanjaneya Manjunath , Qaissi Ahmed Al , Sathyapalan Thozhukat , Atkin Stephen L. , Butler Alexandra E. 
Published: April 2022

AbstractIntroductionThere is evidence that fibroblast growth factor (FGF) levels may be implicated in hypoglycaemia, with FGF19 being a potential contributor to insulin‐independent pathways driving postprandial hypoglycaemia following bariatric surgery and basic FGF (FGF2) being elevated following mild hypoglycaemia occurring after the glucose tolerance test. However, their response following severe iatrogenic hypoglycaemia is unknown and therefore this pilot exploratory study was undertaken.MethodsA case‐control study of aged‐matched type 2 diabetes (T2D; n = 23) and control (n = 23) subjects who underwent a hyperinsulinaemic clamp, initially to euglycaemia in T2D (5 mmol/L; 90 mg/dl), and then to hypoglycaemia (<2 mmol/L; <36 mg/dl) with subsequent follow‐up time course to 24 h. FGF and FGF receptor proteins were determined by Slow Off‐rate Modified Aptamer (SOMA)‐scan plasma protein measurement.ResultsAt baseline, FGF12 (p = .006) was higher and FGF20 (p = .004) was lower in T2D versus controls. At hypoglycaemia, FGF7 was lower in T2D. Post‐hypoglycaemic levels of FGF18, FGF19, FGF20 and FGF23 were lower while FGF12 and FGF16 were higher in T2D versus control at different time points. No differences between T2D and controls were seen for FGF1, FGF2, FGF4, FGF6, FGF8, FGF9, FGF10, FGF21 or any of the FGF receptors. At 24 h post‐hypoglycaemia, FGF20 (p = .01) differed between controls and T2D, while the levels for the other proteins measured returned to baseline. None of the FGF proteins altered from baseline to euglycaemia when clamped in T2D subjects. FGF23 negatively correlated with fasting blood glucose, but no FGFs correlated with body mass index in T2D.ConclusionSevere transient hypoglycaemia modulated FGF7, 16, 19, 20 and 23 (known to be associated with diabetes), together with FGF18 and 12, not previously reported to be associated with diabetes but that may be important in the pathophysiology of hypoglycaemia; FGF20 remained low at 24 h. Taken together, these data suggest that recurrent hypoglycaemia may contribute to the development of complications through changes in FGF proteins.
Banking Union's accountability system in practice: A health check‐up to Europe's financial heart
Authors: Lamandini Marco , Ramos Muñoz David 
Published: April 2022

AbstractThe Single Supervisory Mechanism (SSM) and Single Resolution Mechanism (SRM) form the Banking Union, which comprises EU authorities (ECB and SRB) and national authorities (NCAs and NRAs) with vast powers. Although crucial for its legitimacy, the Banking Union’s accountability is flawed, and not for the (stereo)typical reasons: accountability is a visible concept in SSM and SRM regulations, and political, administrative and judicial bodies are knowledgeable, engaged and thorough. Rather, this article posits that the SSM and SRM work very well because the legislature focused on practical details such as information flows, planning and continuity and coordination, while there has been no comparable effort to ensure the functioning of accountability tools. The result is a “system” characterised by limited access to crucial information, lack of continuity, and uncoordinated functioning. Changing this should not be hard but requires replacing blanket criticism and stereotypical views with greater attention to detail.