bluuebunny/crossref_metadata_2025_split huggingface dataset:
What do we mean by “data”? A proposed classification of data types in the arts and humanities
Authors: Gualandi Bianca , Pareschi Luca , Peroni Silvio 
Published: December 2022

PurposeThis article describes the interviews the authors conducted in late 2021 with 19 researchers at the Department of Classical Philology and Italian Studies at the University of Bologna. The main purpose was to shed light on the definition of the word “data” in the humanities domain, as far as FAIR data management practices are concerned, and on what researchers think of the term.Design/methodology/approachThe authors invited one researcher for each of the official disciplinary areas represented within the department and all 19 accepted to participate in the study. Participants were then divided into five main research areas: philology and literary criticism, language and linguistics, history of art, computer science and archival studies. The interviews were transcribed and analysed using a grounded theory approach.FindingsA list of 13 research data types has been compiled thanks to the information collected from participants. The term “data” does not emerge as especially problematic, although a good deal of confusion remains. Looking at current research management practices, methodologies and teamwork appear more central than previously reported.Originality/valueOur findings confirm that “data” within the FAIR framework should include all types of inputs and outputs humanities research work with, including publications. Also, the participants of this study appear ready for a discussion around making their research data FAIR: they do not find the terminology particularly problematic, while they rely on precise and recognised methodologies, as well as on sharing and collaboration with colleagues.
Comparing vitamin B2 versus 5% dextrose in water for optimal ureteric jet visualisation at the time of pelvic reconstructive surgery: A randomised controlled trial
Authors: Zhao Zi Ying , Lovatsis Danny , Gagnon Louise , Wang Stella , Huszti Ella , McDermott Colleen D. 
Published: December 2022

AbstractObjectiveTo compare preoperative vitamin B2 versus intraoperative cystoscopy distension using 5% dextrose in water (D5W) for ureteric jet visualisation during pelvic reconstructive surgery.DesignDouble‐blinded, randomised controlled trial.SettingThree tertiary hospitals in Toronto, Canada.PopulationAdult women undergoing pelvic reconstructive surgery.MethodsPatients were randomised to receive 100 mg of vitamin B2 preoperatively versus bladder distension with D5W intraoperatively.Main outcomesThe primary outcome was the rate of accurate detection of bilateral ureteric jets during cystoscopy. Secondary outcomes included the time elapsed until visualisation, use of intravenous furosemide or fluorescein to assist with visualisation, surgeon satisfaction, and positive urine culture 1 week after surgery.ResultsThe intervention was completed by 236 patients (vitamin B2 n = 117, D5W n = 119). Preoperative characteristics were similar across groups. Accurate detection of both ureteric jets was high in both groups (vitamin B2 97.4% vs. D5W 90.8%, p = 0.051). The vitamin B2 group had significantly lower use of fluorescein rescue compared with the D5W group (3.4% vs. 11.8%, respectively, p = 0.025). Surgeon satisfaction while using vitamin B2 was significantly higher (p < 0.001). There were no significant differences in the time elapsed until visualisation, the use of furosemide, or the incidence of positive urine culture at 1 week after surgery.ConclusionsBoth preoperative vitamin B2 and intraoperative cystoscopy distension with D5W are highly available and inexpensive methods to detect ureteric jets with high accuracy at the time of pelvic reconstructive surgery. Vitamin B2 was shown to have lower rates of fluorescein rescue for visualisation and higher rates of surgeon satisfaction.
Parathyroid hormone levels and pulse wave velocity in hemodialysis patients
Authors: Kato Kazuhiko , Nakashima Akio , Morishita Masamitsu , Ohkido Ichiro , Yokoo Takashi 
Published: December 2022

AbstractIntroductionWe conducted an observational study to test the hypothesis that intact parathyroid hormone (PTH) levels are independently associated with pulse wave velocity (PWV), indicating arteriosclerosis progression.MethodsIn this cross‐sectional study, patients on hemodialysis in whom brachial‐ankle PWV (baPWV) was measured from November 2020 to November 2021, were included.ResultsOne hundred seventy‐four patients, with a mean age of 69.9 years (standard deviation [SD], 11.9), were included in this study. In multivariate linear regression analysis, serum intact PTH levels were correlated with baPWV (β coefficient: 95% confidence interval [CI], 2.1 [0.22, 3.99]; p = 0.029). The subgroup analysis, which was divided according to the presence of diabetes, showed that diabetes has a significant interaction between PTH and PWV.ConclusionThese results suggest that intact PTH is independently associated with PWV. Moreover, physiological mechanisms characteristic of diabetes may be involved in the association between PTH and arteriosclerosis.
Co‐substrate composition is critical for enrichment of functional key species and for process efficiency during biogas production from cattle manure
Authors: Eliasson Karin Ahlberg , Singh Abhijeet , Isaksson Simon , Schnürer Anna 
Published: December 2022

AbstractCattle manure has a low energy content and high fibre and water content, limiting its value for biogas production. Co‐digestion with a more energy‐dense material can improve the output, but the co‐substrate composition that gives the best results in terms of degree of degradation, gas production and digestate quality has not yet been identified. This study examined the effects of carbohydrate, protein and fat as co‐substrates for biogas production from cattle manure. Laboratory‐scale semi‐continuous mesophilic reactors were operated with manure in mono‐digestion or in co‐digestion with egg albumin, rapeseed oil, potato starch or a mixture of these, and chemical and microbiological parameters were analysed. The results showed increased gas yield for all co‐digestion reactors, but only the reactor supplemented with rapeseed oil showed synergistic effects on methane yield. The reactor receiving potato starch indicated improved fibre degradation, suggesting a priming effect by the easily accessible carbon. Both these reactors showed increased species richness and enrichment of key microbial species, such as fat‐degradingSyntrophomonadaceaeand families known to include cellulolytic bacteria. The addition of albumin promoted enrichment of known ammonia‐tolerant syntrophic acetate‐ and potential propionate‐degrading bacteria, but still caused slight process inhibition and less efficient overall degradation of organic matter in general, and of cellulose in particular.
Cognitive training and remediation interventions for substance use disorders: a Delphi consensus study
Authors: Verdejo‐Garcia Antonio , Rezapour Tara , Giddens Emily , Khojasteh Zonoozi Arash , Rafei Parnian , Berry Jamie , Caracuel Alfonso , Copersino Marc L. , Field Matt , Garland Eric L. , Lorenzetti Valentina , Malloy‐Diniz Leandro , Manning Victoria , Marceau Ely M. , Pennington David L. , Strickland Justin C. , Wiers Reinout , Fairhead Rahia , Anderson Alexandra , Bell Morris , Boendermaker Wouter J. , Brooks Samantha , Bruno Raimondo , Campanella Salvatore , Cousijn Janna , Cox W. Miles , Dean Andrew C. , Ersche Karen D. , Franken Ingmar , Froeliger Brett , Gamito Pedro , Gladwin Thomas E. , Goncalves Priscila D. , Houben Katrijn , Jacobus Joanna , Jones Andrew , Kaag Anne M. , Lindenmeyer Johannes , McGrath Elly , Nardo Talia , Oliveira Jorge , Pennington Charlotte R. , Perrykkad Kelsey , Piercy Hugh , Rupp Claudia I. , Schulte Mieke H. J. , Squeglia Lindsay M. , Staiger Petra , Stein Dan J. , Stein Jeff , Stein Maria , Stoops William W. , Sweeney Mary , Witkiewitz Katie , Woods Steven P. , Yi Richard , Zhao Min , Ekhtiari Hamed 
Published: December 2022

AbstractAimsSubstance use disorders (SUD) are associated with cognitive deficits that are not always addressed in current treatments, and this hampers recovery. Cognitive training and remediation interventions are well suited to fill the gap for managing cognitive deficits in SUD. We aimed to reach consensus on recommendations for developing and applying these interventions.Design, Setting and ParticipantsWe used a Delphi approach with two sequential phases: survey development and iterative surveying of experts. This was an on‐line study. During survey development, we engaged a group of 15 experts from a working group of the International Society of Addiction Medicine (Steering Committee). During the surveying process, we engaged a larger pool of experts (n = 54) identified via recommendations from the Steering Committee and a systematic review.MeasurementsSurvey with 67 items covering four key areas of intervention development: targets, intervention approaches, active ingredients and modes of delivery.FindingsAcross two iterative rounds (98% retention rate), the experts reached a consensus on 50 items including: (i) implicit biases, positive affect, arousal, executive functions and social processing as key targets of interventions; (ii) cognitive bias modification, contingency management, emotion regulation training and cognitive remediation as preferred approaches; (iii) practice, feedback, difficulty‐titration, bias modification, goal‐setting, strategy learning and meta‐awareness as active ingredients; and (iv) both addiction treatment work‐force and specialized neuropsychologists facilitating delivery, together with novel digital‐based delivery modalities.ConclusionsExpert recommendations on cognitive training and remediation for substance use disorders highlight the relevance of targeting implicit biases, reward, emotion regulation and higher‐order cognitive skills via well‐validated intervention approaches qualified with mechanistic techniques and flexible delivery options.
Understanding the impact of pandemics on society with a special focus on COVID‐19
Authors: Malik Sahil , Chhabra Meghna , Chandra Geetika Malik 
Published: December 2022

AbstractThe study aims to ascertain how different levels of society have been influenced by the impact of pandemics over the last many years. The study also determines the societal implications of the COVID‐19 pandemic. The integrative literature survey method is adopted to extract the secondary data pertinent to the socio‐economic effect of pandemics and COVID‐19 on society. Primary data is collected to diagnose the impact of the COVID‐19 pandemic and lockdown on employees (N = 210) working in the Indian organized sector. Findings of the study suggest that pandemics have been a cause of economic slowdown measured with a fall in gross domestic product (GDP) at the macro level. The reduced level of economic activity is found to be negatively related to an individual socio‐economic status building their psychological distress. The descriptive analysis of the data reveals that although employees have managed their jobs and finances during COVID‐19, they have experienced stress in their lives due to the pandemic. The study assimilates the pandemic effect using inductive reasoning to develop a COVID quadrilateral conceptual framework.
Early childhood exposure to maternal smoking and obesity: A nationwide longitudinal survey in Japan
Authors: Yamashita Miho , Yorifuji Takashi , Matsumoto Naomi , Kubo Toshihide , Tsukahara Hirokazu 
Published: December 2022

SummaryInvoluntary exposure to tobacco smoke is suspected to be one of the risks factors that are associated with obesity in children. The purpose of this study was to examine the relationship between early childhood exposure to tobacco smoke and the risk of obesity and overweight in Japan. This study utilized a nationwide, population‐based longitudinal survey. The participants were restricted to 32 081 children who had available information on maternal smoking history as well as childhood height and weight. We conducted a binomial log–linear regression analysis with children of non‐smoking mothers as the reference group. The children with mothers who were smokers had a higher risk of developing obesity or being overweight compared to the children with mothers who were nonsmokers. The risk ratios were 1.20 (95% confidence interval [CI]: 1.09–1.32) for overweight and 1.17 (95% CI: 0.95–1.44) for obesity. Early exposure to maternal smoking increases the risk of being overweight and having obesity during childhood. The increased risk is more pronounced among children with mothers, smoked heavily, or parents, who were smokers.
Feasibility and early effects of bed‐cycling eccentric training: Potential clinical applications
Authors: Pavlin Laura , Fernandez Florian , Lowgreen Rauhiti , Ohresser Isabelle , Cristol Jean‐Paul , Turc‐Baron Cécile , Bernardi Henri , Candau Robin 
Published: December 2022

AbstractPurposeThis study aimed to evaluate feasibility and early effects of moderate intensity bed‐cycling eccentric training on healthy individuals, and establish whether this training modality could be implemented into bedridden patients' routine care.MethodsLongitudinal study with prepost exercise intervention measurements. The development of a bed‐adapted eccentric ergometer allowed to conduct five training sessions during 3 weeks at increasing intensity on 11 healthy individuals. Force‐speed relationship, maximal voluntary knee extension force and neural activation of subjects were evaluated before and after the programme.ResultsFive training sessions were sufficient to decrease the rate of perceived exertion whereas eccentric power output increased (+40%). After training, maximal voluntary isometric contraction force measured during knee extension had significantly improved in all subjects, with a mean increase of 17%. Maximal cycling power was also significantly higher (+7%) after the training programme.ConclusionTaken together, these results show that moderate load eccentric bed cycling (i) was feasible and efficient, (ii) did not generate excessive individual perception of effort during exercise nor develop major muscular or joint pain after training and (iii) allowed early force and power gains in healthy subjects.
N1 versus N2 and PMN‐MDSC: A critical appraisal of current concepts on tumor‐associated neutrophils and new directions for human oncology
Authors: Antuamwine Benedict Boateng , Bosnjakovic Rebeka , Hofmann‐Vega Francisca , Wang Xi , Theodosiou Theodosios , Iliopoulos Ioannis , Brandau Sven 
Published: December 2022

SummaryResearch on tumor‐associated neutrophils (TAN) currently surges because of the well‐documented strong clinical relevance of tumor‐infiltrating neutrophils. This relevance is illustrated by strong correlations between high frequencies of intratumoral neutrophils and poor outcome in the majority of human cancers. Recent high‐dimensional analysis of murine neutrophils provides evidence for unexpected plasticity of neutrophils in murine models of cancer and other inflammatory non‐malignant diseases. New analysis tools enable deeper insight into the process of neutrophil differentiation and maturation. These technological and scientific developments led to the description of an ever‐increasing number of distinct transcriptional states and associated phenotypes in murine models of disease and more recently also in humans. At present, functional validation of these different transcriptional states and potential phenotypes in cancer is lacking. Current functional concepts on neutrophils in cancer rely mainly on the myeloid‐derived suppressor cell (MDSC) concept and the dichotomous and simple N1–N2 paradigm. In this manuscript, we review the historic development of those concepts, critically evaluate these concepts against the background of our own work and provide suggestions for a refinement of current concepts in order to facilitate the transition of TAN research from experimental insight to clinical translation.
Long‐term risk of heart failure and other adverse cardiovascular outcomes in primary Sjögren's syndrome
Authors: Sun Guoli , Fosbøl Emil L. , Yafasova Adelina , Faurschou Mikkel , Lindhardsen Jesper , Torp‐Pedersen Christian , Køber Lars , Butt Jawad H. 
Published: December 2022

AbstractBackgroundData on long‐term cardiovascular outcomes in primary Sjögren's syndrome (PSS) are scarce.ObjectivesWe aim to investigate the long‐term rate of incident heart failure (HF) and other adverse cardiovascular endpoints in patients with PSS compared with the general population and to investigate mortality in individuals with incident HF with or without a history of PSS.MethodsUsing Danish nationwide registries, PSS patients (diagnosed 1996–2018) without a history of other autoimmune diseases were each matched with four individuals from the general population by sex, age, and comorbidities. Multivariable Cox regression was used to estimate the rate of cardiovascular outcomes. In addition, the rate of death from any cause was compared between PSS patients with incident HF and four age‐ and sex‐matched HF patients without PSS.ResultsIn total, 5092 patients with newly diagnosed PSS were matched with 20,368 individuals from the general population (median age 57 years, 87.3% women, median follow‐up 7.4 years). The cumulative incidence of HF at 10 years was 4.0% for PSS patients and 2.8% for matched individuals. After adjustment, patients with PSS had a higher associated rate of incident HF (hazard ratios [HR] 1.42 [95% CI, 1.20–1.68]) and other cardiovascular outcomes, compared with the background population. PSS patients with incident HF had a similar rate of death from all‐cause mortality compared with HF patients without PSS (HR 0.94 [0.74–1.19]).ConclusionsPatients with PSS had a higher associated rate of incident HF and other cardiovascular outcomes compared with the general population. In individuals with incident HF, a history of PSS was not associated with increased mortality.
The administrative burden of doing business with the government: Learning and compliance costs in Business‐Government interactions
Authors: Petersen Ole Helby , Hansen Jesper Rosenberg , Houlberg Kurt 
Published: December 2022

AbstractAdministrative burdens are widespread and likely to generate unequal opportunities in access to government programs and other important entitlements. Whereas a large body of research has examined administrative burdens in citizen‐state encounters, little is known either theoretically or empirically about burdens in business–government interactions. In this article, we argue that private businesses, just like individual citizens, experience administrative burdens in encounters with the government, and that these burdens are the result of bureaucratic procedures as well as the administrative capital resources in the businesses themselves. We present empirical evidence from an original study of Danish businesses' learning and compliance costs in government purchasing contracts. The findings suggest that businesses' learning and compliance costs are shaped more by bureaucratic procedures and requirements than by the administrative capital resources businesses can mobilize in response. We propose steps governments can take to reduce administrative burdens and harness public values in business‐government interactions.
An empirical investigation of the distinction between passive and active ideation: Understanding the latent structure of suicidal thought content
Authors: Wastler Heather M. , Khazem Lauren R. , Ammendola Ennio , Baker Justin C. , Bauder Christina Rose , Tabares Jeffrey , Bryan AnnaBelle O. , Szeto Edwin , Bryan Craig J. 
Published: December 2022

AbstractIntroductionAlthough the distinction between passive and active suicidal ideation is well accepted by suicide researchers and clinicians, there has been very little empirical investigation into this distinction. The current study addressed this gap by examining the latent structure of suicidal ideation based on thought content.MethodParticipants from two distinct samples of U.S. adults (n1 = 6200; n2 = 10,625) completed a self‐report assessment of eight commonly experienced suicidal thoughts using the Self‐Injurious Thoughts and Behaviors Interview‐Revised. Exploratory structural equation modeling was used to examine the latent structure of suicidal thoughts.ResultsThe two‐factor model demonstrated significantly better fit than the one‐factor solution across both samples. Thoughts typically classified as passive ideation strongly loaded onto one factor, whereas thoughts typically classified as active ideation loaded onto the second factor. The two factors were highly correlated and some suicidal thoughts exhibited meaningful cross‐loading.ConclusionOur results suggest that passive and active ideation are two distinct constructs. Although they often co‐occur, passive and active ideation are not nested constructs and should not be viewed as gradients of one underlying construct. Our findings suggest that at a minimum both passive and active ideation should be included in all suicide risk assessments and screenings.
Effects of a Multicomponent Exercise and Therapeutic Lifestyle (CERgAS) Intervention on Gait Function in Lower-Income Urban-Dwelling Older Adults: A Cluster Randomized Controlled Trial
Authors: Loh Debbie Ann , Naqiah Hairi Noran , Mohd Hairi Farizah , Peramalah Devi , Kandiben Shathanapriya , Abd Hamid Mohd Alif Idham , Bulgiba Awang , Salam Mushtahid , Said Mas Ayu , Rizal Hussein , Danaee Mahmoud , Choo Wan Yuen 
Published: December 2022

This study aims to determine the effectiveness of a multicomponent exercise and therapeutic lifestyle (CERgAS) intervention at improving gait speed among older people in an urban poor setting in Malaysia. A total of 249 participants were divided into the intervention (n = 163) and control (n = 86) groups. The mean (SD) age of participants was 67.83 (6.37) and consisted of 88 (35.3%) males and 161 (64.7%) females. A generalized estimating equation with an intention-to-treat analysis was used to measure gait speed at four time points, baseline (T0), 6 weeks (T1), 3 months postintervention (T2), and 6 months postintervention (T3). The results showed significant changes for time between T0 and T3 (mean difference = 0.0882, p = .001), whereas no significant association were found for group (p = .650) and interaction (p = .348) effects. A 6-week intervention is inadequate to improve gait speed. Future efforts should introduce physical activity monitoring and increase exercise duration, frequency, and intensity.