bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sclerosing Mesenteritis Complicated With Mesenteric Lymphoma Responsive to Ustekinumab
Authors: Byriel Ben , Walker Megan , Fischer Monika 
Published: May 2022

ABSTRACT
A 45-year-old man with a 10-year history of biopsy-proven, steroid-dependent sclerosing mesenteritis failed/was intolerant to tamoxifen, azathioprine, colchicine, cyclophosphamide, and methotrexate. He developed osteoporosis, diabetes, and bilateral cataracts. He responded to infliximab but was diagnosed with mesenteric large B-cell lymphoma 6 months after treatment initiation. He achieved remission from lymphoma after chemotherapy, but the sclerosing mesenteritis remained poorly controlled. He was treated with ustekinumab (520 mg intravenously followed by 90 mg subcutaneously every 8 weeks), leading to complete steroid-free remission. He remains symptom and cancer-free 24 months after starting ustekinumab.
Investigating the temperature field distribution over transport structures' metal corrugated construction surface under temperature influences
Authors: Kovalchuk Vitalii , Kravets Ivan , Nabochenko Olga , Petrenko Oleksiy , Milyanych Andriy , Hermaniuk Yuliia , Dzhus Volodymyr 
Published: May 2022

The experimental studies results of temperature distribution over metal corrugated sheet structure surface at positive and negative ambient temperatures are presented. It is established that the temperature is distributed unevenly over the sheet surface along its plane. An analytical method for calculating the temperature field from a fragment of a structure metal sheet in the case of setting the temperature at the sheet area boundaries is presented. The calculation of the temperature field distribution on the metal sheet of the structure with the setting of the temperature along the contour of the sheet is performed. As a result, it is established that at the metal sheet boundaries there is a temperature difference, which can cause the occurrence of temperature stresses and deformations.
SS‐31 does not prevent or reduce muscle atrophy 7 days after a 65 kdyne contusion spinal cord injury in young male mice
Authors: Graham Zachary A. , DeBerry Jennifer J. , Cardozo Christopher P. , Bamman Marcas M. 
Published: May 2022

AbstractSpinal cord injury (SCI) leads to major reductions in function, independent living, and quality of life. Disuse and paralysis from SCI leads to rapid muscle atrophy, with chronic muscle loss likely playing a role in the development of the secondary metabolic disorders often seen in those with SCI. Muscle disuse is associated with mitochondrial dysfunction. Previous evidence has suggested targeting the mitochondria with the tetrapeptide SS‐31 is beneficial for muscle health in preclinical models that lead to mitochondrial dysfunction, such as cast immobilization or burn injury. We gave young male mice a sham (n = 8) or 65 kdyne thoracic contusion SCI with (n = 9) or without (n = 9) daily administration of 5.0 mg/kg SS‐31. Hindlimb muscle mass and muscle bundle respiration were measured at 7 days post‐SCI and molecular targets were investigated using immunoblotting, RT‐qPCR, and metabolomics. SS‐31 did not preserve body mass or hindlimb muscle mass 7 days post‐SCI. SS‐31 had no effect on soleus or plantaris muscle bundle respiration. SCI was associated with elevated levels of protein carbonylation, led to reduced protein expression of activated DRP1 and reductions in markers of mitochondrial fusion. SS‐31 administration did result in reduced total DRP1 expression, as well as greater expression of inhibited DRP1. Gene expression of proinflammatory cytokines and their receptors were largely stable across groups, although SS‐31 treatment led to greater mRNA expression of IL1B, TNF, and TNFRSF12A. In summation, SS‐31 was not an efficacious treatment acutely after a moderate thoracic contusion SCI in young male mice.
The variance of causal effect estimators for binary v-structures
Authors: Kuipers Jack , Moffa Giusi 
Published: May 2022

Abstract
Adjusting for covariates is a well-established method to estimate the total causal effect of an exposure variable on an outcome of interest. Depending on the causal structure of the mechanism under study, there may be different adjustment sets, equally valid from a theoretical perspective, leading to identical causal effects. However, in practice, with finite data, estimators built on different sets may display different precisions. To investigate the extent of this variability, we consider the simplest non-trivial non-linear model of a v-structure on three nodes for binary data. We explicitly compute and compare the variance of the two possible different causal estimators. Further, by going beyond leading-order asymptotics, we show that there are parameter regimes where the set with the asymptotically optimal variance does depend on the edge coefficients, a result that is not captured by the recent leading-order developments for general causal models. As a practical consequence, the adjustment set selection needs to account for the relative magnitude of the relationships between variables with respect to the sample size and cannot rely on purely graphical criteria.
Glutamic acid-glucose Gemini surfactants: physico-chemical properties and effect on the dyeability of polyester fabric
Authors: Lin Li-Huei , Huang Ya-Ting 
Published: May 2022

Abstract
In this study we used glutamic acid as a linking group and glucose, propylene glycol, and fatty alcohols as raw materials to prepare glutamic acid-glucose Gemini surfactants. Fourier transform infrared spectroscopy was used to verify the structures of the surfactants. We investigated their surface properties (surface tension, contact angles), and their effect on the fluorescence of pyrene. To test their potential application, we prepared emulsions with the surfactants and olive oil, and evaluated the emulsion stability with a particle size analyzer. We also investigated the ability to dye polyester fabrics in the presence of the glutamic acid-glucose-gemini surfactants. Among our synthesized materials, those with shorter alkyl chains exhibited better surface activities and emulsification properties, resulting in excellent dye uptake and leveling.
Key Aspects of Rehabilitation for Children at Risk
Authors: Israilova Nodira 
Published: May 2022

This article describes children at risk in the context of a pedagogical problem, analyzes various interpretations of the “rehabilitation” concept in scientific literature and explains the need for rehabilitation work with children in teachers’ practice. On the basis of an empirical review (a questionnaire survey) a spectrum of ideas and opinions of teachers and psychologists from different educational institutions on the goals and objectives of rehabilitation work with children at risk and the main directions for this work in their practical activities have been revealed. In order to analyze the interpretations of specialists’ opinions regarding the nature and assessment of the effectiveness of rehabilitation, a method of collecting qualitative data (questionnaire survey, conversation) with open-ended questions was used. The author summarized the answers of the specialists on the problem under study by the method of content analysis using an open-coding procedure.
According to the results of the research, six rehabilitation contexts have been identified, most specialists consider rehabilitation as comprehensive assistance to children with the aim of successfully returning them to a full social life; involving them into the system of social relations in the course of specially organized education; vocational training; developing healthy lifestyle and law-abiding behavior.
Fonologinių gebėjimų apibrėžtis, įvertinimas bei sąsajos su skaitymo sutrikimu (disleksija)
Authors: Daniutė Simona , Staliūnienė Ingrida 
Published: May 2022

Straipsnyje pateikiama teorinė fonologinių gebėjimų apibrėžties ir struktūros analizė: atskleidžiama fonologinių gebėjimų samprata, jų grupės, sąsajos su skaitymo sutrikimu (disleksija). Taip pat šiame straipsnyje susitelkiama ties išsamiu fonologinių gebėjimų įvertinimo ypatumų tarptautiniu ir nacionaliniu mastu aptarimu.
Teoriniam fonologinių gebėjimų konceptui atskleisti atlikta Lietuvos bei užsienio autorių mokslinių publikacijų analizė. Atlikta koncepto analizė leidžia teigti, kad fonologiniai gebėjimai apima fonologinį suvokimą, trumpalaikę atmintį bei greitą vardijimą. Tai bene dažniausiai užsienio šalyse tyrinėjami fonologiniai procesai, susiję su skaitymu ir(ar) rašymu. Gausūs skirtingomis užsienio kalbomis atlikti tyrimai leido parodyti akivaizdžias fonologinių gebėjimų ir skaitymo sutrikimo (disleksijos) sąsajas. Nustatyta, jog asmenims, turintiems disleksiją, būdingi nepakankami šios srities gebėjimai. Tačiau apžvelgtų ilgalaikių tyrimų rezultatai rodo, jog skaitymo pasiekimus ikimokykliniame ar priešmokykliniame amžiuje geriausiai prognozuoja du rodikliai: fonologinis suvokimas ir greitas vardijimas. Panašaus pobūdžio mokslo darbai, kuriuose analizuojamos fonologinių gebėjimų ir skaitymo lietuvių kalba koreliacijos, kol kas gana reti. Todėl prieš pateikiant tvirtą, moksliniais įrodymais grįstą išvadą šiuo klausimu būtina sukaupti daugiau empirinių duomenų. Taip pat akivaizdus nacionalinių tyrimų apie vaikų, turinčių kalbėjimo ir kalbos sutrikimų, fonologinius gebėjimus, poreikis.
Непересічна постать ученого і педагога
Authors: Гомонай Ганна Миколаївна , Завілопуло Анатолій Миколайович 
Published: May 2022

Статтю присвячено пам’яті відомого українського вченого в галузі ядерної фізики, фізичної і квантової електроніки, лауреата Державної премії України в галузі науки і техніки (1995), заслуженого діяча науки України (1985), лауреата премії ім. К.Д. Синельникова НАН України (1994), одного з патріархів фізичної науки на Закарпатті, засновника кафедр оптики і квантової електроніки в Ужгородському національному університеті, ініціатора створення і першого керівника Ужгородського відділення Інституту ядерних досліджень АН УРСР (нині — Інститут електронної фізики НАН України), доктора фізико-математичних наук (1967), професора (1967) Івана Прохоровича Запісочного. З його ім’ям пов’язані важливі результати, які сприяли розвитку в Україні фізики електронних і атомних зіткнень, спектроскопії вакуумно-ультрафіолетового діапазону, нелінійної оптики, електрон-фотонної та іон-фотонної емісії металевих поверхонь, газової квантової електроніки. Він та його учні зробили вагомий внесок у створення цілої серії оригінальних, у тому числі й унікальних, установок та прецизійного інструментарію для досліджень нових явищ та ефектів в електронній фізиці.
Improving Home Ventilator Alarm Use Among Children Requiring Chronic Mechanical Ventilation
Authors: Pajor Nathan M , Kaiser Michele L , Brinker Megan E , Mullen Lisa A , Schuler Christine L , Hart Catherine K , Britto Maria T , Torres-Silva Cherie A , Hysinger Erik B , Amin Raouf S , Benscoter Dan T 
Published: May 2022

BACKGROUND AND OBJECTIVES
Children requiring long-term mechanical ventilation are at high risk of mortality. Setting ventilator alarms may improve safety, but best practices for setting ventilator alarms have not been established. Our objective was to increase the mean proportion of critical ventilator alarms set for those children requiring chronic mechanical ventilation followed in our pulmonary clinic from 63% to &gt;90%.

METHODS
Using the Institute for Healthcare Improvement Model for Improvement, we developed, tested, and implemented a series of interventions using Plan-Do-Study-Act cycles. We followed our progress using statistical process control methods. Our primary interventions were: (1) standardization of the clinic workflow, (2) development of an algorithm to guide physicians in selecting and setting ventilator alarms, (3) updating that algorithm based on review of failures and inpatient testing, and (4) enhancing staff engagement to change the culture surrounding ventilator alarms.

RESULTS
We collected baseline data from May 1 to July 13, 2017 on 130 consecutive patients seen in the pulmonary medicine clinic. We found that 63% of critical ventilator alarms were set. Observation of the process, standardization of workflow, and adaptation of an alarm algorithm led to an increase to 85.7% of critical alarms set. Through revising our algorithm to include an apnea alarm, and maximizing provider engagement, more than 95% of critical ventilator alarms were set, exceeding our goal. We sustained this improvement through January 2021.

CONCLUSIONS
Our stepwise approach, including process standardization, staff engagement, and integration of an alarm algorithm, improved the use of ventilator alarms in chronically ventilated pediatric patients.
S-Wave Velocity Structure of the Crust and Upper Mantle beneath the North China Craton Determined by Joint Inversion of Rayleigh-Wave Phase Velocity and Z/H Ratio
Authors: Xu Xiaoming , Li Guoliang , Ding Zhifeng , Huang Xiang 
Published: May 2022

Abstract
The North China craton (NCC) is one of the oldest craton in the world. Since the Cenozoic, the NCC has undergone severe lithospheric thinning, accompanied by extensive crustal deformations and volcanic activities. To better understand the mechanisms of the crustal and lithospheric deformations and intraplate volcanisms, we construct a high-resolution 3D S-wave velocity model for the NCC by jointly inverting Rayleigh-wave phase velocity dispersion and Z/H ratio measurements. Across the NCC, our model reveals significant lateral variations. In the shallow crust, prominent low-velocity anomalies associated with thick sediments are resolved in the Bohai Bay basin, and the Ordos basin and its surrounding grabens. Meanwhile, our model also shows that sediments are thin or even missing in the southeast of the Ordos basin and other orogens in the study area. The sedimentary structures of the Bohai Bay basin and the surrounding grabens of the Ordos basin may be the superficial response to the subduction of the Pacific plate and the northeastward push of the Tibetan plateau, respectively. Under the Datong volcano, our model reveals an integrated low-velocity anomalies from the mid-to-lower crust to the mantle, which verifies that the Datong volcano has a deep origin. Besides, the low-velocity zone beneath the eastern NCC (ENCC) connects to the low-velocity anomalies under the Datong volcano in the upper mantle. Combining the previous studies, we further propose that the asthenospheric upwelling of the Datong volcano and the subduction of the Pacific plate may jointly contribute to the lithospheric thinning of the ENCC.
A study to correlate serum pseudocholinesterase and serum creatine phosphokinase levels in acute organophosphorus poisoning with respect to Peradeniya organophosphorus poisoning scale
Authors: K. Yaduraj D. , K. Sahana , S. Sheshan V. , M. Pramila , R. Madhumathi 
Published: May 2022

Background: Organophosphorus insecticides are one of the most common causes of poisoning in India. It has a high mortality rate and accounts for a third of suicidal deaths in south-east Asia.Methods: The objectives were to estimate serum pseudocholinesterase and creatine phosphokinase (CPK) levels in organophosphorus poisoning and correlate them with the severity and prognosis described by the Peradeniya organophosphorus poisoning (POP) scale at initial presentation. This was a cross-sectional study conducted over 18 months. A total of 180 organophosphorus-poisoning subjects were divided into mild, moderate and severe grades based on POP scale at admission. Serum pseudocholinesterase and CPK levels were estimated at admission. The outcome was noted, and the results were statistically analysed.Results: It was found that 112 (62.2%), 51 (28.3%) and 17 (9.4%) patients had mild, moderate and severe poisoning, respectively, according to POP scale. Mean pseudocholinesterase level (units/litre) was 2393.29, 1104.37 and 638.18 and mean serum CPK level (units/ litre) was 153.41, 344.94 and 280.53 in mild, moderate and severe poisoning, respectively. ICU and ventilator were required for 84 (46.75%) and 72 (40%) patients, respectively. Mortality was 17.8%. Negative, weak and significant correlation was seen between POP score and pseudocholinesterase (r=-0.265, p=0.00). Positive, moderate and significant correlation was seen between POP score and CPK levels (r=0.449, p=0.00).Conclusions: POP scale applied at admission along with serum pseudocholinesterase and CPK levels serve as a simple and effective system to determine early need for ventilation and mortality in rural, peripheral centres in developing nations.
Análise do Transporte Cicloviário: Um Estudo de Caso Em Goianésia do Pará
Authors: Costa Taiane Barbosa da Silva , Araújo Alyne Barbosa da Costa , Santos Marlon Braga dos , Araújo Matuzalem dos Santos , Martins Filho Sebastião Pimenta 
Published: May 2022

As cidades brasileiras enfrentam graves problemas de mobilidade urbana, causados em grande parte, pelo padrão de desenvolvimento urbano. A precariedade do transporte coletivo público, bem como, os congestionamentos e acidentes, aliados à falta de infraestruturas necessárias, tem se tornando cada vez mais, agravantes estruturais nas cidades do país. Este artigo propõe uma análise do sistema cicloviário de Goianésia do Pará, interior do estado do Pará. Para isso foi realizado questionário eletrônico, o qual foi aplicado a 41 pessoas residentes no município. Os resultados desta pesquisa apontaram que 92,7% dos entrevistados não utilizam o transporte cicloviário, sendo que 71,1% afirmaram que não fazem uso deste modal por considerarem a infraestrutura do município ruim, além disso, 70,7% considerariam utilizar o modal cicloviário se houvessem locais adequados para o uso, como ciclovias e ciclofaixas.
Osteotomies for the Treatment of Adult Spinal Deformities
Authors: Yilgor Caglar , Kindan Peri , Yucekul Altug , Zulemyan Tais , Alanay Ahmet 
Published: May 2022

» Spinal osteotomies are powerful deformity correction techniques that may be associated with serious complications.» The anatomical spinal osteotomy classification system proposes 6 grades of resection corresponding to different anatomic bone, disc, facet, and ligament interventions.» Surgeons should be aware of the nuances of 3-column osteotomies with regard to spinal level selection, construct composition, and posterior column reconstruction and closure techniques.» There is a global tendency toward avoiding 3-column osteotomies as much as possible because of the growing evidence regarding the effectiveness of posterior column osteotomies and halo-gravity traction.
The Definition of Periprosthetic Osteolysis in Shoulder Arthroplasty
Authors: Hornung Alexander L. , Cohn Matthew R. , Mehta Nabil , McCormick Johnathon R. , Menendez Mariano E. , Pourzal Robin , Nicholson Gregory P. , Garrigues Grant E. 
Published: May 2022

Background:
Periprosthetic osteolysis is a known complication after shoulder arthroplasty that may lead to implant loosening and revision surgery. To date, there is no consensus in the shoulder arthroplasty literature regarding the definition of osteolysis or the grading criteria, thus making it difficult to quantify and compare outcomes involving this complication. The purpose of this study was to perform a systematic review of the literature to assess how periprosthetic osteolysis in shoulder arthroplasty is defined and evaluated radiographically.

Methods:
A systematic review of MEDLINE, Scopus, Cochrane, and CINAHL was performed in August 2021 for studies that provided a definition and/or grading criteria for osteolysis in shoulder arthroplasty. Only studies with a minimum of 2 years of radiographic follow-up were included.

Results:
Thirty-four articles met the inclusion criteria. After consolidating studies by the same primary author that included the same grading criteria, 29 studies were examined for their definition and grading criteria for osteolysis. Of these, 19 (65.5%) evaluated osteolysis surrounding the glenoid and 18 (62.1%) evaluated osteolysis surrounding the humerus. There was considerable heterogeneity in the systems used to grade periprosthetic osteolysis surrounding the glenoid, whereas humeral periprosthetic osteolysis was often categorized via visualization into binary or categorical groups (e.g., presence versus absence; mild, moderate, or severe; partial versus complete). Four studies (13.8%) provided novel measurements for assessing either glenoid or humeral osteolysis.

Conclusions:
Considerable heterogeneity exists in the assessment and grading of periprosthetic osteolysis in shoulder arthroplasty. The most common grading systems were binary and used qualitative visual interpretation, making them relatively subjective and prone to bias. Quantitative measurements of osteolysis were infrequently utilized. A standardized method of assessing osteolysis would be of value to facilitate communication and research efforts.
Airborne Trace Gas Remote Sensing and Surface Mobile In Situ: A Novel Tool for the Study of Structural Geological Controls from a Producing Oil Field
Authors: Leifer Ira , Melton Christopher , Tratt David M. , Buckland Kerry N. 
Published: May 2022

SummaryAccurate and representative determination of greenhouse gases (GHG) from oil and gas (O&G) production facilities requires high-spatial-resolution data, which can be acquired by airborne imaging spectrometers. However, assessment of nonmethane hydrocarbon emissions, which are far less amenable to remote sensing, requires mobile surface in-situ measurements (e.g., a mobile air quality laboratory).Field in-situ measurements and airborne thermal infrared spectral imagery were acquired for three producing California oil fields (Poso Creek, Kern Front, and Kern River) located next to each other on 14 September 2018. In addition, a profile ascending a nearby mountain collected in-situ data for the Round Mountain oilfield. Plume methane to ethane ratios were consistent within different regions of the field and differed between these fields in a manner related to field geological structures.Data acquired by an airborne thermal infrared imaging spectrometer, Mako, in 2015 and 2018 showed most emissions were from distant plumes in the Kern Front and Poso Creek fields. The spatial distribution of detected plumes was strongly related to faults, particularly active faults, which are proposed to stress infrastructure, leading to higher fugitive emissions and/or emissions from natural migration pathways (seepage). Additionally, the spatial distribution of detected plumes suggested unmapped faults. Thus, high-sensitivity imaging spectroscopy can improve understanding of reservoir geological structures that impact hydrocarbon migration and field operations, highlighting the potential for a novel reservoir management tool.