bluuebunny/crossref_metadata_2025_split huggingface dataset:
Typical value ranges and signal patterns in patients with neurogenic bladder: Quality control in urodynamics using an air‐charged catheter system
Authors: Deng Han , Liao Limin , Wu Juan , Li Xing , Pang Dongqing , Liu Qinggang , Wang Xuesheng , Li Xunhua , Liang Ya'nan , Zhou Zhonghan , Luo Runtian , He Panqi 
Published: October 2022

AbstractPurposeTo establish typical value ranges (TVRs) of the air‐charged catheter (ACC) system, and analyze the typical signal patterns (TSPs) of cough under different bladder volumes for quality control of a urodynamic study using the ACC system.Materials and MethodsThe urodynamic traces of 1977 patients with neurogenic bladder (NB) were analyzed for intravesical pressure (pves), abdominal pressure (pabd), and detrusor pressure (pdet) in the cough test at our center from July 2017 to December 2021. The pdet cough signals were described and classified. The pdet cough signal patterns in different bladder volumes and postures were analyzed.ResultsThe 50% range of the initial resting pves, pabd, and pdet in the supine and sitting positions were 7–15, 7–14, and 0–0 cmH2O, and 24–33, 24–33, and 0–0 cmH2O, respectively. The cough amplitudes for pves and pabd were similar in the 50% range, as follows: 10–27 and 8–25 cmH2O in the supine position, respectively; and 18–43 and 17–40 cmH2O in the sitting position, respectively. The cough amplitude of pves and pabd was not related to bladder volume (p > 0.05). The cough spikes of pdet were divided into three types: type I, in which pdet has a minimal change (<5 cmH2O); type II, a monophasic cough spike, in which could be a positive (IIa, ≥5 cmH2O) or negative spike (IIb, ≥5 cmH2O); and type III, a biphasic spike, in which could be a positive‐to‐negative biphasic (IIIa) or negative‐to‐positive spike (IIIb). Under different bladder volumes, the cough signals of pdet were all expressed as type I, II, or III, and the cough signals were unrelated to bladder volume (p > 0.05).ConclusionsTVRs of the initial resting state in patients with NB were established to provide guidance for quantitative quality control of the ACC system. The TSPs of the pdet cough signal under different bladder volume and posture were described, which could be used for qualitative quality control of the ACC system.
‘Like ships in the night’: A qualitative investigation of the impact of childhood cancer on parents’ emotional and sexual intimacy
Authors: Chow Wan Ka , Hetherington Kate , McGill Brittany C. , Sansom‐Daly Ursula M. , Daly Rebecca , Miles Gordon , Cohn Richard J. , Wakefield Claire E. 
Published: October 2022

AbstractBackgroundChildhood cancer is highly distressing for families and can place strain on parents’ relationships. Parental functioning and cohesiveness are important predictors of family functioning and adaptation to stress. This qualitative study investigated the perceived impact of childhood cancer on parents’ relationship with their partner, with a focus on emotional and sexual intimacy.MethodsWe conducted semi‐structured interviews with 48 parents (42 mothers, six fathers) of children under the age of 18 who had completed curative cancer treatment. We analysed the interviews using thematic analysis.ResultsAt interview, parents were on average 40.7 years old (SD = 5.5, range: 29–55 years), and had a child who had completed cancer treatment between 3 months and 10.8 years previously (M = 22.1 months). All participants were living with their partner in a married/de facto relationship. Most parents reported that their child's cancer treatment had a negative impact on emotional and sexual intimacy with their partner, with some impacts extending to the post‐treatment period. Reasons for compromised intimacy included exhaustion and physical constraints, having a shifted focus, and discord arising from different coping styles. Some parents reported that their relationship strengthened. Parents also discussed the impact of additional stressors unrelated to the child's cancer experience.ConclusionsParents reported that childhood cancer had a negative impact on aspects of emotional and sexual intimacy, although relationship strengthening was also evident. It is important to identify and offer support to couples who experience ongoing relationship stress, which may have adverse effects on family functioning and psychological wellbeing into survivorship.
Functional ability before and after rehabilitation in elderly patients with shortening and/or rotational deformity of the lower limb after hip fracture
Authors: Gialanella Bernardo , Santoro Raffaele , Prometti Paola , Monguzzi Vittoria , Comini Laura 
Published: October 2022

AbstractBackgroundShortening and rotational deformity of the lower limb (SRD) is a major complication of hip fracture surgery. It causes not only hip joint dysfunction but also functional impairments due to abnormal gait parameters, decreased gait velocity, and poor balance. Despite a number of previous studies, the effect of SRD on the postsurgical recovery of these patients is still not clear.ObjectiveTo compare the functional abilities and balance before and after rehabilitation for people with and without SRD after hip fracture surgery and to assess whether SRD affects rehabilitation.DesignProspective observational study.SettingInpatients of a rehabilitation unit.ParticipantsA total of 102 people with hip fracture (62 without SRD and 40 with SRD at the time of admission to the unit).Main Outcome MeasuresBerg Balance Scale (BBS) and Functional Independence Measure (FIM) motor score, administered before and after rehabilitation.InterventionsMotor rehabilitation.ResultsBefore rehabilitation, patients with SRD had lower motor‐FIM (p = .002) and BBS (p = .001) scores than those without SRD. After rehabilitation, both groups showed similar improvements in motor‐FIM, BBS, range of motion, muscle strength, and pain scores (p < .001, for all), but patients with SRD still had lower motor‐FIM and BBS scores (p = .014 and .003, respectively) and lower effectiveness in motor‐FIM and BBS (p = .039 and p = .034, respectively) than those without SRD.ConclusionsSRD is associated with lower levels of balance and functional abilities before and after rehabilitation and it adversely affects rehabilitation for patients with hip fractures.
Crystal structure of Campylobacter jejuni lipoprotein Cj1090c
Authors: Paek Seonghee , Kawai Fumihiro , Venisetty Nilamani , Kim Youngchang , Yeo Hye‐Jeong 
Published: October 2022

AbstractIn Gram‐negative bacteria, lipopolysaccharide (LPS) is an essential component of the asymmetric outer membrane (OM). LptE is an OM lipoprotein that forms a complex with the β‐barrel OM protein, LptD. Incorporation of LPS into the OM outer leaflet is essential for bacterial viability, and mediated by the LptD/E complex. The genome of Campylobacter jejuni, a major foodborne pathogen, contains over 20 putative lipoproteins including Cj1090c. Here, we report the crystal structure of Cj1090c at 2.4 Å resolution, revealing structural evidence for LptE in C. jejuni. The analysis of this crystal structure, along with the genomic context, allows us to propose the C. jejuni LPS transport system for the first time, and permits for discussion of the features of the LptD/E complex of C. jejuni.
Support or burden? Mental health and transnational family contact among female migrant domestic workers in Hong Kong
Authors: Lai Yingtong , Fong Eric 
Published: October 2022

AbstractA large and increasing number of female migrant domestic workers has been recorded within the Asia‐Pacific region. Thanks to the development of communication technologies, these migrant women can maintain intimate relations with their family back home despite the distances separating them. However, there have been concerns recently about the effect of preserving close family contact on female migrant domestic workers' mental health. Using recently collected survey data on female migrant domestic workers in Hong Kong, our study finds that daily family communication with parents or partners brings a psychological burden, rather than support, for migrant domestic workers. In addition, the findings show the importance of the workplace environment in moderating the effect of regular family contact. Implications of our findings are discussed.
Riociguat inhibits ultra‐large VWF string formation on pulmonary artery endothelial cells from chronic thromboembolic pulmonary hypertension patients
Authors: Jujo Sanada Takayuki , Manz Xue D. , Symersky Petr , Pan Xiaoke , Yoshida Keimei , Aman Jurjan , Bogaard Harm Jan 
Published: October 2022

AbstractChronic thromboembolic pulmonary hypertension (CTEPH) is characterized by elevated pulmonary arterial pressure and organized thrombi within pulmonary arteries. Riociguat is a soluble guanylate cyclase stimulator and is approved for patients with inoperable CTEPH or residual pulmonary hypertension after pulmonary endarterectomy (PEA). Previous work suggested that riociguat treatment is associated with an increased risk of bleeding, although the mechanism is unclear. The aim of this study is to assess how riociguat affects primary hemostasis by studying its effect on the interaction between platelets and endothelial cells derived from CTEPH patients. Pulmonary artery endothelial cells (PAECs) were isolated from thrombus‐free regions of PEA material. Purified PAECs were cultured in flow chambers and were stimulated with 0.1 and 1 µM riociguat for 24 h before flow experiments. After stimulation with histamine, PAECs were exposed to platelets under shear stress. Platelet adhesion and expression of von Willebrand Factor (VWF) were evaluated to assess the role of riociguat in hemostasis. Under dynamic conditions, 0.1 and 1.0 µM of riociguat suppressed platelet adhesion on the surface of PAECs. Although riociguat did not affect intracellular expression and secretion of VWF, PAECs stimulated with riociguat produced fewer VWF strings than unstimulated PAECs. Flow cytometry suggested that decreased VWF string formation upon riociguat treatment may be associated with suppressed cell surface expression of P‐selectin, a protein that stabilizes VWF anchoring on the endothelial surface. In conclusion, Riociguat inhibits VWF string elongation and platelet adhesion on the surface of CTEPH‐PAECs, possibly by reduced P‐selectin cell surface expression.
Folate ‐ Conjugated Magnetite Nanoparticles for Targeted Drug Delivery and Hyperthermia Applications
Authors: Khan Ahmaduddin , Kumar Sahu Niroj 
Published: October 2022

AbstractResearch in magnetic nanoparticles mediated drug delivery system for cancer therapy is of current demand due to its various attributes. It provides a way for ease of stimuli responsive drug delivery and also act as a hyperthermic agent. Folic acid is extensively used for functionalisation of nanoparticles (NP) as various cancerous cells show overexpression of folate receptors. In this article, we report folic acid conjugated magnetite (Fe3O4) NP by two different ways and characterised by XRD, SEM, UV, FTIR and Raman spectroscopy. The folic acid was conjugated by its amine and carboxyl groups respectively on the magnetite NP to bestow them with targeting abilities. The NP formed are spherical and the size ranges from 32–100 nm and are highly aqueous dispersible as evidenced through the wettability studies. The blank NP shows some cytotoxicity on the MCF‐7 breast cancer cells probably due to oxidative stress. The NP shows high DOX loading efficiency due to higher surface area and negative surface charge. The superior magnetic properties of the NP assures hyperthermic temperature of 41 °C within 49 sec for 2 mg/ml NP concentration at an applied current of 273 A and frequency 316 kHz.
Theoretical Design, Synthesis, Solvatochromic Studies and Non‐Linear Optical Properties of 3,4‐Ethylenedioxythiophene and 3,4‐ Propylenedioxythiophene based Copolymers
Authors: Baby Anju Maria , Savitha D. P. , Sreekumar Krishnapillai 
Published: October 2022

AbstractTwo thiophene based low band gap conjugated copolymers P(EDOT‐NA)] and P(PRDOT‐NA) were designed and synthesized via direct arylation polymerization. The copolymers were characterized by UV‐Vis, IR, Photoluminescence and NMR spectroscopic techniques. HOMO‐LUMO energy levels of the copolymers were theoretically calculated by two levels of DFT theories, HSE06 and B3LYP using a 6‐31G (d,p) basis set. Thermal properties were evaluated by thermogravimetric analysis. Optical properties of the copolymers showed solvatochromic behavior in different tolune/acetonitrile mixtures. P(EDOT‐NA) exhibited a negative solvatochromism in both absorption and emission spectra with a Stoke's shift of 6761 cm−1 to 7218 cm−1. P(PRDOT‐NA) was observed with a negative solvatochromism in absorption and positive solvatochromism in emission with Stoke's shift of 7265 cm−1 to 7891 cm−.1. Third‐order non‐linear optical properties of the copolymers were evaluated using the open‐aperture Z‐scan technique at 532 nm in DMSO solvent. OA Z‐scan behavior and optical limiting effect of the copolymers P(EDOT‐NA) and P(PRDOT‐NA) were studied at 81 μJ, 165 μJ and 300 μJ. Both copolymers exhibited reverse saturable non‐linear optical absorption with positive non‐linear absorption coefficient β (m/W) in the range of 10−10. The optical limiting threshold values obtained for the polymers at 81 μJ were 0.026 GW/cm2 and 0.033 GW/cm2.
Removal of Heavy Metal by Biosurfactant Producing Novel Halophilic Staphylococcus sciuri subsp. rodentium Strain SE I Isolated from Sambhar Salt Lake
Authors: Sharma Priyanka , Rekhi Pavni , Debnath Mousumi 
Published: October 2022

AbstractThe application of halophilic biosurfactant‐producing bacteria to remove the pollutants from textile effluent was investigated in the current study. Staphylococcus sciuri subsp. rodentium strain SE I isolated from Sambhar Salt Lake, Rajasthan showed the highest emulsification activity of 65±1.2 % after 96 h of incubation with a yield of 0.189 g/l of biosurfactant. The surface tension was reduced to 46.23 mN/m±0.46 after 72 h at pH 7.0. The presence of non‐ribosomal protein sequences gave a hint of the presence of surfactin‐type lipopeptide biosurfactant and Copper Translocating P‐type ATPase enzyme sequences indicating its presence can confer resistance against heavy metals. Strain SE I showed the potential to remove heavy metals from textile effluent viz. 67 % of Cd, 64 % of Pb, 59 % of Cu, 50 % of, Cr, and 33 % of Ni after 7 days of treatment as well exhibited decolorization of dyes ranging from 61 %±0.15 to 95 %±1.03, respectively. Based on the research findings, it is reasonable to conclude that surfactin biosurfactant extracted from S. sciuri subsp. rodentium strain SE I can be an alternative biosorbent and function as a bioremediation agent.
Ag/Se‐Catalyzed Selective Epoxidation of β‐Ionone with Molecular Oxygen
Authors: Zhang Xu , Zuo Tingting , Yu Lei 
Published: October 2022

AbstractAg/Se could be easily fabricated by calcining selenium and silver powders. It was found to be an efficient catalyst for the selective epoxidation of the endocyclic C=C bond of β‐ionone to produce β‐ionone epoxide, an important organic intermediate in pharmaceutical industry. It is notable that the reaction can employ molecular oxygen as the cheap, clean and relatively safe oxidant, and no additives such as NHPI are required. The green process makes the method practical for large‐scale application.
Trace-element distribution and ore-forming processes in Au–Ag-rich hydrothermal chimneys and mounds in the TA25 West vent field of the Tonga Arc
Authors: Choi Sun Ki , Pak Sang Joon , Park Jung-Woo , Kim Hyun-Sub , Kim Jonguk , Choi Sang-Hoon 
Published: October 2022

AbstractWe report detailed mineralogy and geochemistry of hydrothermal mounds and chimneys in the TA25 West vent field (TA25 WVF), a newly discovered magmatic–hydrothermal system in the Tonga (Tofua) arc. Chimney samples are classified as sulfate- or sulfide-rich, based on major sulfide, sulfosalt, and sulfate minerals. The former type represents a simple mineral assemblage of predominance of anhydrite/gypsum + barite + pyrite, whereas the sulfide-rich chimneys show three different stages of mineralization with decreasing fluid temperature: sphalerite–pyrite dominated stage I, sphalerite–sulfosalts dominated stage II, and stage III is dominated by seawater alteration. Mound samples are characterized by sulfide assemblages and paragenesis similar to those of sulfide-rich samples, but abundant chalcopyrite indicates a relatively high-temperature mineralization. The chimney and mound samples are enriched in Au (average 9.2 ppm), Ag (297 ppm), As (1897 ppm), Sb (689 ppm), Hg (157 ppm), and Se (34.6 ppm). LA–ICP–MS and FE–TEM studies indicate that most of these elements occur in sulfides or sulfosalts in solid solution, although some occur as nanoparticles. This is mainly controlled by the combined effects of fluid conditions (temperature and redox state) and influx of ambient seawater. Petrography and trace-element compositions of sulfides and/or sulfosalts suggest that most concentrations of Au and Ag in the TA25 WVF result from the precipitation and/or adsorption of Au–Ag-bearing nanoparticles on rapidly crystallized sulfides, the substitution of Au and Ag in sulfide and/or sulfosalt minerals, and the saturation of Ag in hydrothermal fluids during late, relatively low-temperature mineralization (< 150 °C). The maximum measured temperature (242 °C) of venting fluids and calculated formation temperatures of sphalerite (229–267 ℃) are below the boiling temperature of seawater at the depths (966–1096 m) of the TA25 WVF, suggesting fluid boiling had little effect on Au–Ag-rich mineralization in the TA25 WVF. The presence of enargite–tetrahedrite–tennantite assemblages, high concentrations of magma-derived elements (e.g., Au, Ag, As, Sb, Hg, and Se), low δ34S values (2.1 to 4.3‰) of sulfide minerals relative to the host rocks, and the distribution of CO2-rich hydrothermal plumes (500 to 1000 ppm) suggest that the TA25 WVF is a submarine hydrothermal system influenced by a magmatic contribution in an arc setting. Our results indicate that the magmatic contribution is most likely to play an important role in supplying various metals, including Au and Ag, to the TA25 WVF. Subsequently, the rapid crystallization of sulfides induced by abundant fluid-seawater mixing significantly contributes to the precipitation of Au–Ag-rich mineralization.
Characterization of vanillin carbon isotope delta reference materials
Authors: Chartrand Michelle M. G. , Meija Juris , Hélie Jean-Francois , Middlestead Paul , Ramalingam Malarvili , Aziz Azharuddin Abd , Mester Zoltan 
Published: October 2022

AbstractStable carbon isotope ratio measurements are used to investigate the provenance of vanillin. In this study, a variety of commercial vanillin samples and vanilla products were analyzed to provide a frame of reference for the variability of carbon isotope delta values in various vanillin samples, with the results ranging from −20.6 to −36.7‰ relative to the Vienna Peedee Belemnite (VPDB). We present information on the development of two synthetic vanillin reference materials, VANA-1 and VANB-1, prepared in 0.75 g units in glass vials, to be used for the calibration of carbon isotope delta measurements of vanillin and other easily combustible organic materials. Characterization of 40 vials each of VANA-1 and VANB-1 was performed by three laboratories over several measurement sequences. The certified carbon isotope delta values are −31.30 ± 0.06‰ (VANA-1) and −25.85 ± 0.05‰ (VANB-1). These uncertainties, for the 95% confidence level, include considerations for measurement uncertainty, coherence of the reference materials used for calibration, batch homogeneity, and stability during storage and transportation. The results are traceable to the VPDB through a set of nine reference materials (IAEA-CH-6, USGS65, IAEA-600, NBS22, USGS61, IAEA-603, IAEA-610, IAEA-611, and IAEA-612). For up to date certified values, users should refer to doi.org/10.4224/crm.2022.vana-1 and doi.org/10.4224/crm.2022.vanb-1.
Dynamic mechanical characteristics of aged silicone rubber blend
Authors: Mwafy Eman A. , Gaafar M. S. 
Published: October 2022

AbstractThe effect of aging on the mechanical properties of silicone rubber (SR) was investigated by means of ultrasonic, dynamic mechanical analysis, and FTIR techniques. Both longitudinal and shear (Ultrasonic wave velocities) were measured at room temperature and at frequencies of 2 MHz. Density, molar volume, ultrasonic wave velocities, tensile strength, mechanical properties, and FT–IR showed the improvement of the silicone rubber network with aging time from 0 to 70 days, while loosening of the network structure was observed at 14 days and 50 days aging. These behaviours were explained in terms of the change in cross-link density and average stretching force constant of bonds with aging. Thermogravimetric analysis and differential scanning calorimetric techniques showed quite low thermal stability and temperature performance for aged SR at 14 and 50 days than virgin SR which was confirmed by the cracks and voids appeared under scanning electron microscope.
Adversarial attacks on graph-level embedding methods: a case study
Authors: Giordano Maurizio , Maddalena Lucia , Manzo Mario , Guarracino Mario Rosario 
Published: October 2022

AbstractAs the number of graph-level embedding techniques increases at an unprecedented speed, questions arise about their behavior and performance when training data undergo perturbations. This is the case when an external entity maliciously alters training data to invalidate the embedding. This paper explores the effects of such attacks on some graph datasets by applying different graph-level embedding techniques. The main attack strategy involves manipulating training data to produce an altered model. In this context, our goal is to go in-depth about methods, resources, experimental settings, and performance results to observe and study all the aspects that derive from the attack stage.
The climate benefit of sequestration in soils for warming mitigation
Authors: Crow Susan E. , Sierra Carlos A. 
Published: October 2022

AbstractSoils are an enticing reservoir for nature-based climate solutions, but long timescales are required to store amounts of C of relevance to mitigate warming acknowledging its impermanence. Scientific clarity on the controlling factors in soil C persistence should help to disambiguate debates related to permanence in the climate policy domain. However, another contributing factor that is lacking in this debate is a way to compute the climate benefits of C in terrestrial ecosystems over time in the same units as greenhouse gas emissions. We use a case study approach here to demonstrate the use of the metrics of carbon sequestration (CS) and climate benefit of sequestration (CBS) with the aim of assessing the contribution of simultaneous emissions and uptake on radiative forcing. We show how this new computational framework quantifies the climate benefit achieved in two different agricultural systems, one a managed tropical perennial grass system in Hawaiʻi, USA and the other a boreal (cold-temperate, semi-humid) agricultural soil from long term amendment trials in Sweden. Using a set of computations, we show how C inputs and persistence interact to produce different levels of radiative forcing at relevant time frames, which could greatly help to clarify issues of carbon permanence discussed in climate policy. Temporary soil C storage could help to decrease peak warming provided that ambitious emission reductions are part of the portfolio of solutions; the CS and CBS framework gives us a way to quantify it based on biogeochemical understanding of soil C persistence.