bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimal interconnection of three‐terminal tandem solar cells
Authors: Schulte‐Huxel Henning , Witteck Robert , Blankemeyer Susanne , Köntges Marc 
Published: November 2022

AbstractThree‐terminal (3T) tandem solar cells require an adapted module integration scheme in order to explore their full efficiency potential. The three terminals allow to extract the power of the top and bottom cell separately. In a cell string, the wide bandgap top cells are interconnected in parallel to multiple bottom cells resulting in a parallel/series interconnection. This interconnection scheme affects the operation of the subcells, the resulting current path between the subcells, the layout of the cell interconnects, and the system level. Here, we analyze by simulations and experiments the aspects of the module integration of series‐ and reverse‐connected 3T cells with their practical impact on module processes and performance as well as the effect of varying voltage ratios on the string‐end losses. If the subcells are connected in series, the module integration requires insulation layers and significantly longer interconnects compared to devices with reverse‐connected subcells. Tandem devices with a reverse connection and a voltage ratio between top and bottom cell of 2:1 allow a lean interconnection design and low integration losses. We present an approach for the integration of bypass diodes for the protection against shading effects that allow to minimize string‐end and shading losses for a system of modules featuring 3T cells.
Isolation, Cytotoxicity Evaluation, Docking, ADMET and Drug Likeness Studies of Secondary Metabolites from the Stem Bark ofAnthocephalus cadamba(Roxb.)
Authors: Gupta Nidhi , Qayum Arem , Singh Shashank , Mujwar Somdutt , Sangwan Payare L. 
Published: November 2022

AbstractPhytochemical investigation of the stem bark ofAnthocephalus cadamba(Rubiaceae) led to the isolation of total ten secondary metabolites (1‐10) including β–sitosterol (1), ursolic acid (2), vanillic acid (3), quinovic acid (4), 3‐O‐[α‐L‐rhamnopyranosyl]‐quinovic acid (5), β‐sitosterol β‐D‐glucoside (6), cadambine (7), 3β‐dihydrocadambine (8), 7‐O‐acetyl loganin (9) and hexylp‐coumarate (10). Four acetylated derivatives2 a,5 a,7 aand8 aobtained through acetylation of compounds2,5,7and8respectively. All the compounds characterized using1H and13CNMR, HRESIMS and IR and comparison with literature. Compound4showed the best cytotoxic activity with IC50value 4 and 7 μM against pancreatic (MIA‐pa‐Ca‐2) and leukemia (HL‐60) cancer cells respectively. Docking results supported the anticancer potential of compound4viainhibition of EGFR receptor (PDB ID:3POZ) and its pharmacokinetic profile found optimized as per the Lipinski's filter. Therefore compound4has the potential to be developed as an anticancer agent against pancreatic cancer cells.
Synthesis, Spectroscopic, Computational, Biological and Molecular docking studies on 3‐allyl 2,6‐diaryl piperidin‐4‐ones
Authors: Manjula V. , Venkateswaramoorthi R. , Dharmaraja J. , Bharanidharan S. 
Published: November 2022

AbstractA series of 3‐allyl‐2,6‐diarylpiperidin‐4‐one derivatives were designed and synthesized as antimicrobial agents with good yields. The target compounds were characterized by Mass, NMR, FT‐IR and FT‐Raman spectral techniques. The optimization had been performed on the title compound using the B3LYP method with 6‐311++G(d,p) basis set. The optimized bond parameter of the title molecule was calculated by DFT method. To study the intramolecular charge transfer within the molecule, the Lewis (bonding) and Non‐Lewis (anti‐bonding) structural calculation was performed. The Non‐linear optical behaviour of the title compound was measured using first order hyperpolarizability calculation. Mulliken atomic charges and thermodynamic properties were also calculated and analyzed. In vitro antibacterial and antifungal screening for all the synthesized 3‐allyl 2,6‐diaryl piperidin‐4‐ones was evaluated for two Gram‐positive bacteria (Staphylococcus aurous, Enterococcus faecalis), three Gram‐negative bacteria Pseudomonas aeruginosa, Escherichia coliand K. pneumonia) and five fungi (Candida albicans, Aspergillus niger, Aspergillus flavus, Rhizopus sp and Mucor sp). All the compounds showed good antibacterial and antifungal activities. Molecular docking study is to demonstrate that piperidine derivatives bind to Ribonucleotide reductases (RNRs) enzymes and to evaluate whether these molecules can be used as potential drugs.
Epoxidation of unsaturated fatty acid ester promoted by imidazolium acidic ionic liquids: An unexpected selectivity phenomena
Authors: Nowicki Janusz , Nowakowska‐Bogdan Ewa , Lukosek Marek 
Published: November 2022

AbstractEpoxidation of linseed oil fatty acid ethyl esters promoted by a series of functionalized imidazolium ionic liquids was studied. In this reaction acidic imidazolium ILs behave not only as an acid catalysts but also play an additional role as a specific activator for the reaction of epoxidation of unsaturated fatty derivatives in H2O2/formic acid oxidation system. The obtained results indicate that the hydrogen‐bonding interaction of imidazolium cation with epoxide group influences the selectivity of the epoxidation reaction. In particular, the presence of unprotected weak “acid” C2‐H proton significantly lowers the selectivity to hydroxyl derivatives. The obtained results also point to another example of specific polyfunctionality of ILs, especially imidazolium one, used as surfactants and process activators.
Utilization of palliative care resource remains low, consuming potentially avoidable hospital admissions in stage IV non-small cell lung cancer: a community-based retrospective review
Authors: Meggyesy Austin M. , Buehler Kerrie E. , Wilshire Candice L. , Chiu Shih Ting , Chang Shu-Ching , Rayburn Joshua R. , Gilbert Christopher R. , Gorden Jed A. 
Published: November 2022

Abstract

Purpose
Early referral of patients with stage IV non-small cell lung cancer (NSCLC) to outpatient palliative care has been shown to increase survival and reduce unnecessary healthcare resource utilization. We aimed to determine outpatient palliative care referral rate and subsequent resource utilization in patients with stage IV NSCLC in a multistate, community-based hospital network and identify rates and reasons for admissions within a local healthcare system of Washington State.

Methods
A retrospective chart review of a multistate hospital network and a local healthcare system. Patients were identified using ICD billing codes. In the multistate network, 2844 patients diagnosed with stage IV NSCLC between January 1, 2013, and March 1, 2018, were reviewed. In the state healthcare system, 283 patients between August 2014 and June 2017 were reviewed.

Results
Referral for outpatient palliative care was low: 8% (217/2844) in the multistate network and 11% (32/283) in the local healthcare system. Early outpatient palliative care (6%, 10/156) was associated with a lower proportion of patients admitted into the intensive care unit in the last 30 days of life compared to no outpatient palliative care (15%, 399/2627; p = 0.003). Outpatient palliative care referral was associated with improved overall survival in Kaplan Meier survival analysis. Within the local system, 51% (104/204) of admissions could have been managed in outpatient setting, and of the patients admitted in the last 30 days of life, 59% (87/147) experienced in-hospital deaths.

Conclusion
We identified underutilization of outpatient palliative care services within stage IV NSCLC patients. Many patients with NSCLC experience hospitalization the last month of life and in-hospital death.
Innovation in assessment of the geothermal energy potential of abandoned hydrocarbon wells in the southern and southeastern foreground of the Bükk Mountains, northeast Hungary
Authors: Szűcs Péter , Turai Endre , Mádai Viktor , Vass Péter , Miklós Rita , Zákányi Balázs , Ilyés Csaba , Fekete Zsombor , Kilik Roland , Móricz Ferenc , Nyiri Gábor , Szilvási Marcell , Szabó Norbert Péter 
Published: November 2022

AbstractAn innovative methodology is introduced to study abandoned oil exploration drillings for possible geothermal energy production at a test area in northeast Hungary. An evaluation method supported by robust statistical analysis was elaborated to provide the possible future investors with adequate technical and earth-science related information for their decision-making processes. All the available data of 161 abandoned hydrocarbon wells, with different physical conditions, were examined based on the proposed evaluation system to provide information about the geothermal energy potential for each well, as well as over a bigger area. The abandoned wells and their environments, the quantity of stored heat, and the fluid temperature and geothermal heat were the key parameters determined, which are critical when considering geothermal energy utilization or thermal water production. The maximum amount of stored energy was determined as the sum of the amount of energy extractable from the rock and the fluid. The heat stored in the rock was determined by basin modelling. The evaluation process, using one-dimensional (1D) basin modelling and 3D lithological-stratigraphic modelling, was successfully applied in the pilot area. The maximum amount of heat stored in the fluid can be determined by subtracting the heat stored in the rock from the total heat. Drilling and completing geothermal wells are rather expensive in Hungary, depending on the depth and the types of geological formations. The application of this research could greatly reduce the cost and risk of creating new geothermal energy systems based on production wells or abandoned wells in Hungary or elsewhere.
Investigating the MIS2 Microlithic Assemblage of Umbeli Belli Rockshelter and Its Place Within the Chrono-cultural Sequence of the LSA Along the East Coast of Southern Africa
Authors: Blessing Matthias A. , Conard Nicholas J. , Bader Gregor D. 
Published: November 2022

AbstractSouth Africa is arguably one of the most studied regions in Stone Age research. There are, however, considerable differences in research intensity with respect to different regions and time periods. While KwaZulu-Natal is an epicenter for Middle Stone Age (MSA) research, the Late Pleistocene LSA record is largely understudied in this region. Here we present a lithic assemblage from the site Umbeli Belli near Scottburgh dated to 17.8 ± 1.5ka BP. The lithic analysis of the GH 3 assemblages revealed both gradual and abrupt changes within this stratigraphic horizon, indicating relatively short-term changes in material cultural traditions. A comparison with other Robberg sites in the wider surroundings highlights the regional variability of the Robberg techno-complex and indicates potential directions for future research.
Sosa’s AAA Model and Epistemic Double Effects
Authors: Liz Gutiérrez Antonio Manuel 
Published: November 2022

AbstractThere are many important connections between epistemic justification and moral justification. A recent example of such connections is offered by Sosa’s AAA model for the normative evaluation of epistemic performances. In order to count as knowledge, a belief has to be Accurate in attaining the truth, the subject has to be Adroit or competent for such task, and the belief has to be Apt in the sense that the accuracy of the belief has to manifest the adroitness of the subject. In addition, full knowledge would require full-aptness, which is obtained when the aim of aptness is achieved in an apt way. We have here a clear definition of the model. But the application of the model to particular performances is not so clear. Both the identification of a particular performance as a case of epistemic performance and the assessment of its aptness, or full-aptness, are strongly relative to intentional descriptions paying attention to contextual factors and personal aspects. Here is where we can find close proximity with ethics. An epistemic analog to the ethical problem of double effects appears. In our paper, we analyze that problem in detail, extracting some consequences.
HADHA alleviates hepatic steatosis and oxidative stress in NAFLD via inactivation of the MKK3/MAPK pathway
Authors: Ding Jiexia , Wu Lili , Zhu Guoxian , Zhu Jing , Luo Pingping , Li Youming 
Published: November 2022

Abstract
Background
Nonalcoholic fatty liver disease (NAFLD) is a liver metabolic syndrome and still lacks effective treatments because the molecular mechanism underlying the development of NAFLD is not completely understood. We investigated the role of Hydroxyl CoA dehydrogenase alpha subunit (HADHA) in the pathogenesis of NAFLD.

Methods
HADHA expression was detected both in NAFLD cell and mice, and knockdown of HADHA in free fatty acids (FFA)-treated L02 or overexpression of HADHA in high fat diet (HFD)-fed mice was used to detected the influence of HADHA on hepatic steatosis, mitochondrial dysfunction, and oxidative stress by regulating of MKK3/MAPK signaling.

Results
Our data revealed that HADHA expression was decreased in FFA-treated L02 cells and in HFD-fed mice. Knockdown of HADHA markedly aggravated hepatic steatosis, inflammation and oxidative stress in FFA-treated L02 cells, which was associated with the activation of MKK3/MAPK signalling pathways. Moreover, oxidative stress and liver lesions were improved in NAFLD mice by upregulation of HADHA. Importantly, we demonstrated that overexpression of HADHA inhibited the expression of p-MAPK in NAFLD mice, reducing lipid accumulation and steatosis.

Conclusion
HADHA may function as a protective factor in the progression of NAFLD by alleviating abnormal metabolism and oxidative stress by suppressing MKK3/MAPK signalling pathway activation, providing a new target for the treatment of NAFLD.
A comprehensive analysis of acknowledgement texts in Web of Science: a case study on four scientific domains
Authors: Smirnova Nina , Mayr Philipp 
Published: November 2022

AbstractAnalysis of acknowledgments is particularly interesting as acknowledgments may give information not only about funding, but they are also able to reveal hidden contributions to authorship and the researcher’s collaboration patterns, context in which research was conducted, and specific aspects of the academic work. The focus of the present research is the analysis of a large sample of acknowledgement texts indexed in the Web of Science (WoS) Core Collection. Record types “article” and “review” from four different scientific domains, namely social sciences, economics, oceanography and computer science, published from 2014 to 2019 in a scientific journal in English were considered. Six types of acknowledged entities, i.e., funding agency, grant number, individuals, university, corporation and miscellaneous, were extracted from the acknowledgement texts using a named entity recognition tagger and subsequently examined. A general analysis of the acknowledgement texts showed that indexing of funding information in WoS is incomplete. The analysis of the automatically extracted entities revealed differences and distinct patterns in the distribution of acknowledged entities of different types between different scientific domains. A strong association was found between acknowledged entity and scientific domain, and acknowledged entity and entity type. Only negligible correlation was found between the number of citations and the number of acknowledged entities. Generally, the number of words in the acknowledgement texts positively correlates with the number of acknowledged funding organizations, universities, individuals and miscellaneous entities. At the same time, acknowledgement texts with the larger number of sentences have more acknowledged individuals and miscellaneous categories.
Labor productivity, labor impact, and co-authorship of research institutions: publications and citations per full-time equivalents
Authors: Stock Wolfgang G. , Dorsch Isabelle , Reichmann Gerhard , Schlögl Christian 
Published: November 2022

AbstractIndicators of productivity and impact of research institutions are based on counts of the institution members’ publications and the citations those publications attracted. How can scientometricians count publications and citations on the meso-level (here, institution level)? There are three variables: the institution’s scientific staff in the observed time frame, their publications in that time, and the publications’ citations. Considering co-authorship of the publications, one can count 1 for every author (whole counting) or 1/n for n co-authors (fractional counting). One can apply this procedure to publications as well as citations. New in this article is the consideration of complete lists of scientific staff members, which include the exact extent of employment, to calculate the labor input based on full-time equivalents (FTE) and also of complete lists of publications by those staff members. This approach enables a size-independent calculation of labor productivity (number of publications per FTE) and labor impact (number of citations per FTE) on the meso-level. Additionally, we experiment with the difference and the quotient between summarizing values from the micro-level (person level) and aggregating whole counting values directly on the meso-level as an indicator for the institution’s predominant internal or external co-authorship.
Understanding the increasing market share of the academic publisher “Multidisciplinary Digital Publishing Institute” in the publication output of Central and Eastern European countries: a case study of Hungary
Authors: Csomós György , Farkas Jenő Zsolt 
Published: November 2022

AbstractAs the open access movement has gained widespread popularity in the scientific community, academic publishers have gradually adapted to the new environment. The pioneer open access journals have turned themselves into megajournals, and the subscription-based publishers have established open access branches and have turned subscription-based journals into hybrid ones. Maybe the most dramatic outcome of the open access boom is the market entry of such fast-growing open access publishers as Frontiers and Multidisciplinary Digital Publishing Institute (MDPI). By 2021, in terms of the number of papers published, MDPI has become one of the largest academic publishers worldwide. However, the publisher’s market shares across countries and regions show an uneven pattern. Whereas in such scientific powers as the United States and China, MDPI has remained a relatively small-scale player, it has gained a high market share in Europe, particularly in the Central and Eastern European (CEE) countries. In 2021, 28 percent of the SCI/SSCI papers authored/co-authored by researchers from CEE countries were published in MDPI journals, a share that was as high as the combined share of papers published by Elsevier and Springer Nature, the two largest academic publishers in the world. This paper seeks to find an explanation for the extensively growing share of MDPI in the publication outputs of CEE countries by choosing Hungary as a case study. To do this, by employing data analysis, some unique features of MDPI will be revealed. Then, we will present the results of a questionnaire survey conducted among Hungary-based researchers regarding MDPI and the factors that motivated them to publish in MDPI journals. Our results show that researchers generally consider MDPI journals’ sufficiently prestigious, emphasizing the importance of the inclusion of MDPI journals in Scopus and Web of Science databases and their high ranks and impacts. However, most researchers posit that the quick turnaround time that MDPI journals offer is the top driver of publishing in such journals.
A direct proof of the Sharp Gårding inequality for symbols with limited smoothness
Authors: Cicognani Massimo 
Published: November 2022

AbstractWe give a proof of the (possibly optimal) Sharp Gårding inequality for system operators with symbol of limited smoothness directly from the original symmetrization arguments by Friedrichs and Kumano-Go. The fact that only a few derivatives of the regularized symbol are really important was already there.
An effective strategy for preparing transparent ceramics using nanorod powders based on pressure-assisted particle fracture and rearrangement
Authors: Huang Zhangyi , Shi Yang , Zhang Yutong , Deng Mao , Guo Yi , Kong Qingquan , Qi Jianqi , Ma Benyuan , Wang Qingyuan , Wang Haomin 
Published: November 2022

AbstractAchieving full densification of some ceramic materials, such as Y2O3, without sintering aids by spark plasma sintering (SPS) is a great challenge when plastic deformation contributes limitedly to the densification as the yield stress of the material at an elevated temperature is higher than the applied sintering pressure. Herein, we demonstrate that particle fracture and rearrangement is an effective strategy to promote the densification during the pressure-assisted sintering process. Specifically, Y2O3 nanocrystalline powders composed of nanorod and near-spherical particles were synthesized and sintered at various temperatures by the SPS. The results show that the relative density of the ceramics prepared by the nanorod powders is higher than the density of the ceramics from the near-spherical powders after 600 °C due to the fracture and rearrangement of the nanorods at low temperatures, which leads to the decrease of particle size and the increase of density and homogeneity. Based on this novel densification mechanism, ultrafine-grained Y2O3 transparent ceramics with good optical and mechanical properties were fabricated successfully from the nanorod powders.
An attempt to understand plagiarism in Kuwait through a psychometrically sound instrument
Authors: Erguvan Inan Deniz 
Published: November 2022

AbstractThe purpose of this study is to understand student perceptions towards plagiarism and identify some factors influencing their plagiarist behaviour to be able to develop successful strategies to promote academic integrity and prevent plagiarism. Although academic dishonesty and plagiarism have been investigated by many researchers, psychometric qualities of these data collection instruments have generally been ignored, which has resulted in a shortage of standardized and validated questionnaires in the literature. Therefore, to address this issue the researcher ran a rigorous psychometric analysis on a previously developed and psychometrically evaluated questionnaire (Attitudes Towards Plagiarism). The modified instrument was conducted on 404 students studying in a private university in Kuwait in March 2022, representing the first administration of a psychometrically established plagiarism scale in the Kuwaiti context. The statistical analysis revealed that students’ perceptions are significantly different according to the high school type they graduated from, their reasons for studying at the university, and their post-graduation career plans, whereas gender, major and year of study do not cause statistically significant differences.
Solanaceae pangenomes are coming of graphical age to bring heritability back
Authors: Usadel Björn 
Published: November 2022

Abstract
Two recent articles describe a pangenome of potato and a graph-based pangenome for tomato, respectively. The latter improves our understanding of the tomato genomics architecture even further and the use of this graph-based pangenome versus a single reference dramatically improves heritability in tomato.