bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Scalable Risk-Scoring System Based on Consumer-Grade Wearables for Inpatients With COVID-19: Statistical Analysis and Model Development
Authors: Föll Simon , Lison Adrian , Maritsch Martin , Klingberg Karsten , Lehmann Vera , Züger Thomas , Srivastava David , Jegerlehner Sabrina , Feuerriegel Stefan , Fleisch Elgar , Exadaktylos Aristomenis , Wortmann Felix 
Published: May 2022

Background
To provide effective care for inpatients with COVID-19, clinical practitioners need systems that monitor patient health and subsequently allow for risk scoring. Existing approaches for risk scoring in patients with COVID-19 focus primarily on intensive care units (ICUs) with specialized medical measurement devices but not on hospital general wards.

Objective
In this paper, we aim to develop a risk score for inpatients with COVID-19 in general wards based on consumer-grade wearables (smartwatches).

Methods
Patients wore consumer-grade wearables to record physiological measurements, such as the heart rate (HR), heart rate variability (HRV), and respiration frequency (RF). Based on Bayesian survival analysis, we validated the association between these measurements and patient outcomes (ie, discharge or ICU admission). To build our risk score, we generated a low-dimensional representation of the physiological features. Subsequently, a pooled ordinal regression with time-dependent covariates inferred the probability of either hospital discharge or ICU admission. We evaluated the predictive performance of our developed system for risk scoring in a single-center, prospective study based on 40 inpatients with COVID-19 in a general ward of a tertiary referral center in Switzerland.

Results
First, Bayesian survival analysis showed that physiological measurements from consumer-grade wearables are significantly associated with patient outcomes (ie, discharge or ICU admission). Second, our risk score achieved a time-dependent area under the receiver operating characteristic curve (AUROC) of 0.73-0.90 based on leave-one-subject-out cross-validation.

Conclusions
Our results demonstrate the effectiveness of consumer-grade wearables for risk scoring in inpatients with COVID-19. Due to their low cost and ease of use, consumer-grade wearables could enable a scalable monitoring system.

Trial Registration
Clinicaltrials.gov NCT04357834; https://www.clinicaltrials.gov/ct2/show/NCT04357834
Assessment of Smartphone Apps for Common Neurologic Conditions (Headache, Insomnia, and Pain): Cross-sectional Study
Authors: Minen Mia T , George Alexis , Camacho Erica , Yao Leslie , Sahu Ananya , Campbell Maya , Soviero Mia , Hossain Quazi , Verma Deepti , Torous John 
Published: May 2022

Background
There are thousands of apps for individuals struggling with headache, insomnia, and pain, but it is difficult to establish which of these apps are best suited for patients’ specific needs. If clinicians were to have access to a platform that would allow them to make an informed decision on the efficacy and feasibility of smartphone apps for patient care, they would feel confident in prescribing specific apps.

Objective
We sought to evaluate the quality of apps for some of the top common, disabling neurologic conditions (headache, insomnia, and pain) based on principles derived from the American Psychiatric Association’s (APA) app evaluation model.

Methods
We used the Mobile Health Index and Navigation database and expanded upon the database’s current supported conditions by adding 177 new app entries. Each app was rated for consistency with the APA’s app evaluation model, which includes 105 objective questions based on the following 5 major classes of consideration: (1) accessibility, (2) privacy and security, (3) clinical foundation, (4) engagement style, and (5) interoperability. These characteristics were evaluated to gain a broader understanding of the significant features of each app category in comparison against a control group.

Results
Approximately 90% (187/201) of all apps evaluated were free to download, but only 50% (63/201) of headache- and pain-related apps were truly free. Most (87/106, 81%) sleep apps were not truly free to use. The apps had similar limitations with limited privacy, accessibility, and crisis management resources. For example, only 17% (35/201) of the apps were available in Spanish. The apps offered mostly self-help tools with little tailoring; symptom tracking was the most common feature in headache- (32/48, 67%) and pain-related apps (21/47, 45%), whereas mindfulness was the most common feature in sleep-related apps (73/106, 69%).

Conclusions
Although there are many apps for headache, pain, and insomnia, all 3 types of apps have room for improvement around accessibility and privacy. Pain and headache apps share many common features, whereas insomnia apps offer mostly mindfulness-based resources. Given the many available apps to pick from, clinicians and patients should seek apps that offer the highest-quality features, such as complete privacy, remedial features, and the ability to download the app at no cost. These results suggest that there are many opportunities for the improvement of apps centered on headache, insomnia, and pain.
The p66Shc protein mediates insulin resistance and secretory dysfunction in pancreatic beta-cells under lipotoxic conditions
Authors: Biondi Giuseppina , Marrano Nicola , Dipaola Lucia , Borrelli Anna , Rella Martina , D’Oria Rossella , Genchi Valentina A. , Caccioppoli Cristina , Porreca Immacolata , Cignarelli Angelo , Perrini Sebastio , Marchetti Piero , Vincenti Leonardo , Laviola Luigi , Giorgino Francesco , Natalicchio Annalisa 
Published: May 2022

<p> We evaluated the role of the p66Shc redox adaptor protein in pancreatic beta-cell insulin resistance that develops under lipotoxic conditions and with excess body fat. Prolonged exposure to palmitate in vitro or the presence of overweight/obesity augmented p66Shc expression levels and caused an impaired ability of exogenous insulin to increase cellular insulin content and secreted C-peptide levels in INS-1E cells and human and murine islets. In INS-1E cells, p66Shc knockdown resulted in enhanced insulin-induced augmentation of insulin content and C-peptide secretion and prevented the ability of palmitate to impair these effects of insulin. Conversely, p66Shc overexpression impaired insulin-induced augmentation of insulin content and C-peptide secretion both in the absence and presence of palmitate. Under lipotoxic condition, the effects of p66Shc are mediated by p53-induced increase in p66Shc protein levels and JNK-induced p66Shc phosphorylation at Ser36 and appear to involve the phosphorylation of the ribosomal protein S6 kinase at Thr389 and of insulin receptor substrate-1 at Ser307, resulting in the inhibition of insulin-stimulated protein kinase b phosphorylation at Ser473. Thus, the p66Shc protein mediates the impaired beta-cell function and insulin resistance induced by saturated fatty acids and excess body fat. </p>
Peningkatan Kemampuan Penalaran Matematik Siswa Melalui Pendekatan Keterampilan Proses Matematika
Authors: . Juariah 
Published: May 2022

Pendekatan pembelajaran diupayakan harus dapat mengaktifkan siswa, dan mengembangkan kemampuan memecahkan masalah serta daya nalar siswa, sehingga siswa mampu mengembangkan dan mengevaluasi argumentasi. Salah satu pendekatan yang bisa melibatkan berbagai aktivitas siswa adalah pendekatan keterampilan proses. Proses pengajaran dengan keterampilan proses akan membentuk siswa yang terampil dalam intelektual dan terampil dalam proses perhitungan. Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan pendekatan keterampilan proses matematika dalam meningkatkan kemampuan penalaran siswa MTs.N 1 Kota Bandung. Metode penelitian yang digunakan adalah metode eksperimen, dengan Disain penelitian yang digunakan berbentuk pretest-postest-control group, yaitu disain kelompok kontrol pretes dan postes yang melibatkan dua kelompok. Dua kelompok tersebut, yaitu kelompok kontrol dan kelompok eksperimen. Perbedaan antara kedua kelompok tersebut adalah perlakuan dalam proses belajar-mengajar. Eksperimen proses belajar-mengajarnya memperoleh perlakuan dengan pendekatan keterampilan proses matematika, sedangkan kelompok kontrol memperoleh pengajaran biasa. Hasil penelitian ini menunjukkan bahwa Terdapat perbedaan peningkatan kemampuan penalaran matematis antara siswa yang mendapat pembelajaran dengan pendekatan keterampilan proses matematika dan siswa yang mendapat pembelajaran biasa. Kemampuan penalaran matematis siswa yang mendapat pembelajaran dengan pendekatan keterampilan proses matematika lebih baik dibandingkan siswa yang mendapat pembelajaran biasa. Dengan demikian pembelajaran matematika siswa dengan pendekatan keterampilan proses dapat meningkatkan kemampuan penalaran matematis siswa.
Centenario del partido: tendencias y sobresaltos durante 2021 en China
Authors: Haro Navejas Francisco Javier 
Published: May 2022

Este trabajo sobre China y Hong Kong durante 2021 cubre apenas algunos aspectos de lo acontecido en su seno o de aquello que les afectó. El eje del texto es el evento político principal del año: el centésimo aniversario del Partido Comunista Chino (PCC). Alrededor de esta celebración se ordenaron los discursos y las acciones de la élite política dominante en China, entre los que sobresalen todos los eventos realizados para celebrar la fundación del partido y la liberación de Meng Wanzhou en Canadá, para no hablar de cada uno de los discursos de Xi Jinping, presidente y secretario general del PCC. Se describen parcialmente las crisis de un gigante de bienes raíces y la de la generación de energía, temas encuadrados dentro de las previsiones que se presentaron públicamente sobre los acontecimientos que podrían haberse avecinado. El artículo examina diferentes aspectos de las relaciones internacionales de China con algunos países de las Américas, entre ellos Canadá, Estados Unidos, México y algunos de América del Sur, como Brasil, Chile y Ecuador. Dado el contexto actual, se presta atención relevante a las relaciones con Australia y los cambios que se producen en el statu quo de la región. La demografía es un tema clave en el texto, que analiza el censo de 2020, cuyos resultados fueron dados a conocer en 2021. Otros aspectos presentes incluyen el mundo laboral, el cine y la política dentro de la industria de la moda. En el caso de Hong Kong se abordan las secuelas de la Ley de Seguridad Nacional y la aprobación de las reformas a la ley electoral, así como las propuestas económicas para poner esta región administrativa especial sobre sus pies.
Tailandia
Authors: Ramírez Didou Pablo Henri 
Published: May 2022

2021 ha sido un año complicado para Tailandia. La pandemia del coronavirus, que parecía dominada en 2020, terminó por afectar todos los aspectos de la vida tailandesa. El gobierno de Prayuth Chan-o-cha ha tenido que enfrentar la gestión sanitaria de la pandemia, la crisis política que ésta ha ocasionado en el país, el movimiento estudiantil que busca una reforma social y política, así como las tensiones existentes entre sus socios regionales de la ASEAN y la guerra comercial entre China y Estados Unidos.
Difference-in-differences test for micro effect of technological finance cooperation pilot in China
Authors: Li Guiping , Liu Wei 
Published: May 2022

Abstract
By establishing difference in differences (DID) and propensity score matching-double difference method (PSM-DID) models, the paper investigates the effect of the two pilot policies which promotes the combination of technology and finance based on the enterprise value with the available data from Shanghai and Shenzhen A-share listed companies in China from 2008 to 2019. Empirical results show that the first and second pilots of technological finance cause a significant increase and decrease in the enterprise value, respectively. These conclusions validate the effectiveness of China's technological finance policy from the enterprise value and provide empirical data support for optimising technological finance policies of the government and high-quality development of enterprises in the new era.
Comparison of the Old and New - Novel Mechanisms of Action for Anti-coronavirus Nucleoside Analogues
Authors: Thames Joy E. , Seley-Radtke Katherine L. 
Published: May 2022

Over the past two and a half years the world has seen a desperate scramble to find a treatment for SARS-CoV-2 and COVID. In that regard, nucleosides have long served as the cornerstone to antiviral treatments due to their resemblance to the naturally occurring nucleosides that are involved in numerous biological processes. Unlike other viruses however, it was found early on during the search for drugs to treat SARS-1 and later MERS, that the coronaviruses possess a unique repair enzyme, an exonuclease (ExoN)[3] which rendered nucleoside analogues useless, thus negating their use.[4] During the current outbreak however, as both well-known and new nucleoside analogues were investigated or reinvestigated as a possible cure for SARS-CoV-2, several novel and/or lesser-known mechanisms of action were uncovered. This review briefly describes these mechanisms.
KOMPARASI FEMINISME PADA PUISI WENI SURYANDARI DAN RUPI KAUR
Authors: Faridah Siti , Hartati Dian 
Published: May 2022

The purpose of this study is to describe a comparison of feminist views on two poems by Indonesian poets and Indian poets. The poems compared by the researchers include the title "Perempuan Perkasa" written by Weni Suryandari and the poem entitled "Kaur a Woman of Shiki" written by the Indian poet Rupi Kaur. The approach used is comparative literature, which is an attempt to compare two or more literary works from different countries, such as two works of poetry from Indonesia and India. This research is a comparative study with the object of research in the form of feminism views contained in the two poems. The data collection method used in this research is the documentation method. The results of the research on Weni Suryandari's poetry introduce an assumption that a woman has extraordinary strength, she is able to be a man's support and even a woman can protect a man. Meanwhile, Rupi Kaur's poetry shows that women have freedom and women also have the ability to be pillars of those around them. Keywords: Literature Comparative, Feminism, Poetry
PERBANDINGAN ANALISIS STRUKTURAL CERITA RAKYAT “LEGENDA MATAHARI DAN PEMANAH ULUNG” ASAL JAMBI DAN CERITA PENDEK “HOUI DAN CHANA” ASAL JEPANG
Authors: Firdaus Muhamad Yuda , Hartati Dian 
Published: May 2022

The research was conducted to see two literary works from different countries, languages, and cultures but have similarities and differences in them. The creation of literary works cannot be separated from the culture of society. The source of the research data is the Jambi Indonesian folklore “The Legend of the Sun and the Ultimate Archer” with the short story “Houi dan Chana” by Siahara Akemi. The research uses a qualitative research paradigm. The findings show that the similarities between the two literary works can be seen in the storyline, which has a forward plot and language style using language that is easy to understand and there is a personification style. The differences are in the theme, characters and characterizations, setting, point of view, and mandate. The folklore has the theme of regret from a cruel king, while the short story has the theme of kindness being repaid by cruelty. There are four characters in folklore while in short stories there are five characters. In folklore the setting is in the clouds and at night, while in the short story the setting is in heaven, the house, and the mountain and the setting is nearing night. The point of view in folklore uses a third-person omniscient point of view, while in short stories it uses a mixed point of view. The mandate in folklore is that as a king, don't be cruel, and repent by not committing cruel acts anymore is the best way to atone for sins that have been committed. While in the short story, it is still doing good even though getting a bad reply.Keywords: Structural analysis, comparative analysis, folklore, short story
KAJIAN SASTRA BANDINGAN CERPEN GADIS KOREK API DENGAN CERPEN TERESA : PENDEKATAN PSIKOLOGI SASTRA
Authors: Naziha Silvi Athala , Hartati Dian 
Published: May 2022

This research is important to do in order to determine the psychological condition that occurs in a woman as a follow-up and the violence she experienced. This study aims to describe the differences and similarities in the main female characters in the title Gadis Korek Api by Djenar Maesa Ayu with the poem Teresa by Paulina Flores. The method used in this research is descriptive analysis. The technique used in this research is reading and notetaking technique. The approach taken is using the Psychological Theory of Sigmund Freud (1923) there are three personality elements in psychoanalysis, namely the Id, Ego, and Superego. The results of the study reveal that (1) there are similarities in the two literary works, namely actions against women, (2) differences in the main female characters in the two works, as Nayla has a different ego personality from Id. Meanwhile, Claudia in Teresa's short story is more dominant in personality I than following Ego. Keywords: Comparative Literature, Psychology, Short Stories.
STRATEGI KETIDAKSANTUNAN DALAM VIDEO DEBAT PEMILIHAN PRESIDEN TAHUN 2019
Authors: Gustiani Tia , Aslinda Aslinda , Usman Fajri 
Published: May 2022

The goal of this article is to identify and explain impoliteness strategies in the 2019 presidential election debate and to evaluate the role of impoliteness used in the 2019 presidential debate. Qualitative descriptive is the kind of method that used by the researcher. The data was gathered from four YouTube videos of the 2019 presidential election debates and analyzed using the distributional and identity methods. This study used the theory of impoliteness by Jonathan Culpeper (2005) which withhold politeness, sarcasm or mock politeness, negative impoliteness, positive impoliteness, dan bald on record impoliteness. Based on the research result, it is found negative impoliteness was the most frequent impoliteness strategy, accounting for 43%. The speaker demonstrated his superiority by accusing and condemning the flaws of others in this strategy.Keywords: Impoliteness, Impoliteness Strategies, Debate, Election
MODEL PERENCANAAN KEUANGAN DALAM MENINGKATKAN AKSESIBILITAS NELAYAN PALABUHANRATU PADA PERBANKAN SYARIAH
Authors: Kurnia Tuti , Munawar Wildan , Apriyana Maya , Apriliansyah Muhammad Romi , Wijaya Aldi , Risdiani Risma , Syah Aulia Yasmin , Syaifussalam Syidiq 
Published: May 2022

Tujuan dari penelitian ini adalah untuk menyusun model perencanaan keuangan bagi nelayan agar meningkatkan aksesibilitas nelayan terhadap lembaga keuangan syariah khususnya perbankan syariah, sehingga nelayan tidak lagi terjerat dalam lingkaran rentenir. Metode penelitian dilakukan dengan menggunakan pendekatan kualitatif. Metode pengembilan sampel dengan melakukan interview mendalam terhadap 16 nelayan di Palabuhanratu. Hasil penelitian menunjukan bahwa model yang dapat diimplementasikan adalah model PERKENEL yaitu model perencanaan pengelolaan keuangan bagi nelayan yang disusun dalam rangka meningkatkan aksesibilitas nelayan dalam meningkatkan aksesibilitas nelayan terhadap lembaga keuangan dalam hal ini adalah lembaga keuangan syariah. Model ini melibat beberapa lembaga dan organisasi dan dapat diterapkan pada nelayan yang memiliki kelompok bukan nelayan individu. Fokus dari model ini adalah peningkatan peran ketua kelompok nelayan dan penyediaan produk perbankan syariah khusus bagi nelayan yang menggabungkan antara tabungan nelayan dan pembiayaan bagi nelayan.
Analisis Deskriptif Burnout Mahasiswa Bimbingan dan Konseling Selama Pembelajaran Daring
Authors: Lianawati Ayong 
Published: May 2022

Penelitian dilatarbelakangi oleh meningkatnya intensitas screen time dan terbatasnya interaksi selama perkuliahan daring diperkirakan akan berdampak pada kelelahan dan stress mahasiswa selama pembelajaran daring, yang dikenal dengan istilah burnout. Selain itu semakin banyaknya tuntutan dalam perkuliahan daring pun meningkatkan kemungkinan burnout pada mahasiwa BK, khususnya di prodi BK UNIPA Surabaya. Penelitian bertujuan untuk menditeksi dan menggambarkan sejauh mana burnout dialami oleh mahasiswa salama perkuliahan daring. Metode penelitian menggunakan analisis deskriptif. Sampel penelitian berjumlah 146 orang yang diambil secara random dari tiga semester berjalan (Ganjil) tahun akademik 2020/2021 di program studi BK UNIPA Surabaya. Data diperoleh dengan menggunakan skala burnout yang mengacu pada empat domain/ aspek burnout. Bentuk skala yang digunakan adalah skala likert. Analisis data menggunakan rumus kategorisasi, dan persentase. Hasil penelitian menunjukkan 17 orang sampel mengalami burnout dalam kategori rendah (11.6%),102 sampel mengalami burnout dalam kategori sedang (69.9%), dan 27 orang sampel mengalami burnout dalam kategori tinggi (18.5%).
Studi Eksplorasi Muatan Pendidikan Karakter dalam Tradisi Makkobar Boru pada Masyarakat Batak Angkola
Authors: Pane Siti Maryam , Priyono Cipto Duwi , Sormin Salman Alparis 
Published: May 2022

Masalah pokok yang dikemukakan sebagai landasan penelitian ini adalah kerisauan tentang pendidikan karakter yang belum maksimal saat ini, sehingga diperlukan kajian pendidikan karakter bermuatan lokal. Tujuan penelitian yang akan dicapai dalam penelitian ini yaitu untuk menemukan dan menguji muatan pendidikan karakter dalam tradisi makkobar boru pada masyarakat Batak Angkola di Kota Padangsidimpuan. Metode penelitian Metode penelitian yang digunakan untuk memperoleh data penelitian menggunakan metode kualitatif eksploratif. Data penelitian dianalisis dengan Teknik Miles dan Huberman yang terdiri dari pengumpulan data, kondensasi data, display data dan penarikan kesimpulan. Hasil penelitian menemukan dua aspek penting dalam tradisi makkobar boru yaitu masyarakat Batak Angkola masih mempertahankan tradisi makkobar boru sebagai salah satu cara mentransmisikan nilai-nilai kebudayaannya kepada anak pada saat menikah. Kemudian dalam tradisi makkobar boru terdapat sejumlah nilai-nilai pendidikan karakter antara lain: nilai religius, nilai jujur dan setia, nilai toleransi, nilai bekerja keras dan nilai bertanggung jawab. Sebagai kesimpulan dari hasil penelitian ini adalah tradisi makkobar boru merupakan bagian dari proses pelestarian nilai-nilai luhur budaya masyarakat Batak Angkola melalui sejumlah ritual yang sarat akan makna pendidikan.
Pengaruh Optimisme dan Penerimaan Diri terhadap Kecenderungan Post Power Syndrome pada Kepala Sekolah Negeri di Kota Surabaya Menjelang Pensiun
Authors: Pertiwi Ananda Puspita , Yoenanto Nono Hery 
Published: May 2022

Penelitian ini bertujuan untuk mengetahui pengaruh optimisme dan penerimaan diri terhadap kecenderungan post power syndrome pada kepala sekolah negeri di Kota Surabaya yang menjelang pensiun. Penelitian ini dilakukan pada kepala sekolah negeri di Kota Surabaya dengan jumlah responden sebanyak 36 subyek. Proses pengumpulan data menggunakan metode survei, dan alat ukur yang digunakan yaitu skala optimisme (43 aitem; α = 0,891), skala penerimaan diri (42 aitem; α = 0,925), dan skala post power syndrome (33 aitem; α = 0,967). Hasil penelitian menunjukkan terdapat pengaruh optimisme dan penerimaan diri terhadap kecenderungan post power syndrome pada kepala sekolah negeri di Kota Surabaya menjelang pensiun. Dengan nilai R square sebesar 0,731 yang artinya besar pengaruh optimisme dan penerimaan diri terhadap kecenderungan post power syndrome adalah 73%, sedangkan 27% dipengaruhi oleh variabel lain yang tidak diuji dalam penelitian ini. Selain itu pada uji parsial (t) nilai unstandardized B pada optimisme adalah -0,652 dan penerimaan diri -0,611. Sedangkan pada uji simultan (f) diketahui nilai taraf signifikansi dari model ANOVA adalah 0,000. Kesimpulan dari penelitian ini adalah terdapat pengaruh optimisme dan penerimaan diri terhadap kecenderungan post power syndrome pada kepala sekolah negeri di Kota Surabaya menjelang pensiun.