bluuebunny/crossref_metadata_2025_split huggingface dataset:
Developing an English Mobile App by Adapting Gender Education Values for English Language Teaching
Authors: Adisti Aprilian Ria , Guritno Agung 
Published: August 2022

The desire to promote gender equality and women’s empowerment is reflected in Indonesia as a mark of the country’s support for the global initiatives of the United Nations Millennium Declaration. In reality, the data shows that Indonesian women are still lagging compared to men in the education aspect. Hence, the values of gender education and women empowerment could be internalized in all subjects at school, one of them being English Language Teaching (ELT). This study aims at designing, developing, and adapting gender equality and women empowerment values into the mobile app for ELT for teaching descriptive text for 7th-grade students in Junior High Schools. This research implemented Research & Development which used interviews and questionnaires as the instruments. There were three stages applied in this research adopted from Thiagarajan, Semmel, and Semmel (1974) which were defined, designed, and develop. The result showed that the results of expert validation showed that this mobile app is feasible to be implemented. Furthermore, this simple mobile app can integrate the values of gender equality and women empowerment through descriptive texts in English Language Teaching for grade 7th Junior High School.
Obtaining substituted phenol derivatives with potential antimicrobial activity
Authors: Sokhraneva V. A. , Yusupova D. A. , Boriskin V. S. , Groza N. V. 
Published: August 2022

Objectives. With the growing resistance of pathogenic microorganisms to antibiotics, the development of new antimicrobial drugs offering specific mechanisms of action becomes an urgent task. Only few antimicrobials offer a broad spectrum of activity against gram-positive and gram-negative bacteria, molds, and yeasts. In this regard, the purpose of the work was to develop methods for synthesizing biologically active derivatives of alkyl-substituted phenols (reactions at the hydroxy group) to study their biological effect.Methods. The synthesis of imidazole acetates of substituted phenols was carried out in two stages. At the first stage, the chloroacetyl derivative of the selected compounds was obtained, to which imidazole was then added. O-acylation reactions at the first stage of the synthesis were carried out under varying conditions. The first version of the synthesis was carried out using chloroacetyl chloride as an acylating agent together with a high-boiling solvent. In the second variant, chloroacetic anhydride was used, along with an attempt to replace the solvent with a low-boiling one. A thymol methoxy derivative was additionally synthesized by a known method using methyl iodide and varying the reaction parameters.Results. The parameters of chloroacetylation and methoxylation of aromatic alcohols were optimized with rational selection of solvents and the ratio of reagents in the reactions. Synthesized thymol (2-isopropyl-5-methylphenol) and propofol (2,6-isopropylphenol) derivatives contained imidazole as an additional pharmacophore with affinity for microorganism cell membrane proteins. A thymol methoxy derivative comprising an aromatic ether exhibiting increased hydrophobicity was also obtained. The synthesized compounds were characterized by NMR spectroscopy.Conclusions. Chloroacetyl derivatives of aromatic alcohols can be effectively synthesized by cooling the reaction mixture using an excess quantity of an acylating agent and increasing the reaction time (compared to literature data). The yield of thymol chloroacetate was 75%, while that of propofol chloroacetate was 30%. This can be explained by the sterically hindered reaction of the propofol alcohol group, which has isopropyl substituents at the second and sixth positions of the benzene ring.
Validation of a method for the quantitative determination of narcotic and psychotropic substances in urine by UHPLC–MS/MS
Authors: Savelieva N. B. , Ishutenko G. V. , Polosin A. V. , Radus F. V. , Polyansky D. S. , Kurbatkin S. A. , Efimova Yu. A. , Postnikov P. V. 
Published: August 2022

Objectives. To validate a new method for the quantitative determination of 31 potent and narcotic substances and their metabolites in urine that meets the requirements of ISO/IEC 17025 using a fast and highly sensitive method of chromato-mass spectrometry with a view to introducing such a method into the routine practice of the National Anti-Doping Laboratory of the Lomonosov Moscow State University (NADL MSU).Methods. Urine samples soldered with standard solutions were analyzed using ultra high performance liquid chromatography-tandem mass spectrometry (UHPLC–MS/MS).Results. Diagnostic precursor/ion-product pairs and collision energies were established to allow unambiguous identification of the analyzed substances. During sample preparation, hydrolysis conditions were optimized. Selectivity, linearity, limits of qualitative determination, limit of quantitative determination (established under the contract with the customer firm), matrix effect, and measurement uncertainty were defined. Systematized data grouped by classes of analytes are given in the final table.Conclusions. The important advantages of the presented technique are the absence of complex and lengthy sample preparation, as well as the short time of the analysis method (about 10 min), which can significantly reduce duration along with labor and analysis costs. The addition of new analytes will ensure the versatility of the technique, as well as expanding its scope.
Collective dynamics of domain structures in liquid crystalline lipid bilayers
Authors: Kadantsev V. N. , Goltsov A. N. 
Published: August 2022

Objectives. Numerous studies of biosystems indicate the distinct role of quasi-one-dimensional molecular structures in the transport of energy, charges, and information. Of particular interest are the studies on the collective dynamics of quasi-one-dimensional lateral structures in liquid crystalline membranes and the possibility of local excitation transfer through such structures. In this paper, we developed a model for the collective dynamics of quasi-one-dimensional domain structures in lipid bilayers interacting with the environment. The objective is to study the mechanisms of the directed energy transport in liquid crystalline lipid membranes.Methods. In this paper, the percolation domain structures formed as a result of phase separation in multicomponent lipid membranes are considered to be quasi-one-dimensional domain structures. The model distinguishes two subsystems interacting with each other and differing in their structural and dynamic properties, i.e., the membrane surface formed by polar groups of lipid molecules and the internal hydrophilic region of the membrane formed by acyl chains of lipids. The acyl chain subsystem is simulated using the Ginzburg-Landau Hamiltonian which considers the dependence of its dynamics on temperature close to the lipid melting phase transition temperature Tc.Results. Analysis of dynamic states has shown that elastic excitations moving at constant rate in the form of solitons may exist near temperatures Tc in the considered quasi-one-dimensional domain structures. In addition, motion of the elastic excitation region (kink) along domain structures in the acyl chain region causes the formation of acoustic soliton, i.e., the compression region in the polar group subsystem moving in concert with the kink displacement. The soliton localization region covers about 10 molecules and depends significantly on the interaction parameter of the polar group and acyl chain subsystems. Soliton moves at a subsonic speed determined, in particular, by the magnitude of an external force.Conclusions. The model developed in this paper shows that liquid crystalline domain structures in lipid membranes exhibit properties of active media, wherein the formation and displacement of localized elastic excitations on macroscopic spatial and temporal scales may occur. The proposed molecular mechanism of the soliton transport along quasi-one-dimensional domain structures may be used for describing the directed energy transfer along lateral domain channels in biomembranes and the cooperative functioning of the membrane bioenergetic and receptor complexes.
Nonreciprocal propagation of spin waves in a bilayer magnonic waveguide based on yttrium-iron garnet films
Authors: Odintsov S. A. , Lock E. H. , Beginin E. N. , Sadovnikov A. V. 
Published: August 2022

Objectives. Nonreciprocal spin wave effects can manifest themselves in metalized films of ferrite garnets. By studying the dynamics of spin waves in micro- and nano-scale magnetic films, the possibility of using multilayer dielectric films of yttrium iron garnet (YIG) to ensure the manifestation of the nonreciprocity effect is demonstrated. This approach offers advantages compared to the use of a layered YIG/metal structure due to significantly lower spin-wave losses in the two-layer YIG film consisting of layers with different values of magnetization. Such films can be used in logical elements to create controllable Mach-Zehnder interferometers based on magnonic principles. The purpose of this work is to reconcile the concept of nonreciprocal spin-wave propagation of a signal with the simultaneous manifestation of the effects arising from the propagation of spin waves in microwave guides formed by finite-width YIG films.Methods. We used an experimental microwave spectroscopy method based on a vector network analyzer along with a finite difference method to perform a numerical simulation of the dispersion characteristics of spin waves in two-layer magnonic microwave guides. An analytical model was also used to obtain a dispersion equation based on the magnetostatic approximation.Results. Based on measurements of the amplitude and phase responses, the possible coexistence of two frequency ranges for the propagation of a spin-wave signal in a two-layer magnon microwave guide based on a YIG film formed by two layers with different values of saturation magnetization was demonstrated. Regimes of nonreciprocal propagation of a spin-wave signal were revealed. A numerical model was using to study the formation mechanisms of spin wave modes in the spectrum of a two-layer structure formed due to the finite dimensions of the microwave guide. An analytical model was used to evaluate the transformation of the mode spectrum. The experimental data are in good agreement with the results of the proposed numerical and analytical models.Conclusions. The possibility of frequency-selective propagation of spin waves in a magnon microwaveguide consisting of two layers with different saturation magnetization values is demonstrated. Multimode propagation of spin waves can occur inside a two-layer structure in two frequency ranges. At the same time, this process is accompanied by a strong nonreciprocity of spin-wave signal propagation, which manifests itself in a change in the amplitude and phase responses when the direction of the external magnetic field is reversed. The proposed two-layer spin-wave waveguide concept can be used in the manufacture of magnon interconnects and magnon interferometers with the support of multiband regimes of operation.
Pengembangan Pertanian Tebu Di Kabupaten Sleman Dan Dampaknya Terhadap Kondisi Sosial – Ekonomi Petani: Studi Pada Koperasi Tebu Sido Makmur
Authors: Yusuf Ilma Fatimah 
Published: August 2022

Sleman Regency is a productive area, its agriculture is known to support food security. This is proven by the various awards given by the Minister of Agriculture, one of which is a member of the Sido Makmur sugar cane farmer cooperative, which is located in Kalasan District, Sleman Regency. The award that can be obtained is, of course, due to the development of sugarcane farming. So, the purpose of this research is to examine the development of sugarcane farming and its impact on socio-economic conditions, which is focused on the Sido Makmur Cooperative.
The method in this study uses descriptive analysis, with purposive sampling technique. While the data collection techniques were carried out by means of observation, interviews and documentation. The data analysis uses data reduction techniques, categorization, data display and drawing conclusions.
The results of the study show several things. The first, sugarcane farmers who are members of the Sido Makmur Cooperative have a maximum education up to high school level. Second, the land cultivated by sugarcane farmers is varied, at least 1.5 Ha, while at most 10 Ha. There is land that is cultivated on a lease basis, but there is also one that is owned by yourself. Third, cooperatives have a role in the development of sugarcane agriculture through the steps of forming a business unit for the procurement of retail fertilizer sales, rental of agricultural production equipment, savings and loans and building relationships with sugar factories. Fourth, the role of the cooperative can encourage members of sugarcane farmers to remain productive and as an effort to improve the welfare of members.
Pola Kemitraan Ayam Ras Pedaging Pola Kemitraan Ayam Ras Pedaging dan Pengaruh Karakteristik Peternak, Pendapatan serta Pelayanan Perusahaan terhadap Loyalitas Kerjasama	(Studi di PT. Semesta Mitra Sejahtera, Kabupaten Tulungagung)
Authors: Nurihayanti Onny 
Published: August 2022

Poultry business development is a reliable business, providing a significant increase in income, opening up employment opportunities, a source of fulfilling community nutrition and supporting the industrial sector. General Director of PKH (2020) said that East Java's chicken meat production in 2018 was 480,309.46 tons, in 2019 it was 506,731.16 tons and in 2020 it was as high as 474,868.84 tons. Economic conditions will foster competition among business actors, especially for large-scale business actors, the small farmers will suffer even more due to various limitations. The solution that can provide a solution to the problem of developing a poultry business, especially broilers, is through a partnership pattern. This study aims to determine the effect of breeder characteristics (X1), income (X2) and company services (X3) on loyalty cooperation (Y) partnership pattern at PT. Semesta Mitra Sejahtera, Tulungagung. This type of research is a survey research using 60 samples. Collecting data using a questionnaire method with a Likert scale, observation and interviews. Data analysis using SPSS 24 includes classical assumption test and multiple linear regression analysis to test the hypothesis. Resulting of the regression analysis show the function equation Y = 0.159 + 0.143X1 + 0.003X2 + 0.844X3+e has a coefficient of determination (R2) of 0.822, means that cooperation loyalty is influenced by breeder characteristics, income and company services of 82.2%. The result of hypothesis test are stated: an influence between the characteristics of breeders on cooperation loyalty (H1 is accepted), nothing effect between breeders' income on cooperation loyalty (H2 is rejected) and influence between company services on cooperation loyalty (H3 is accepted).
Recensioni
Authors: Tosi Silvia 
Published: August 2022

-Spagnuolo Lobb M., Cavaleri P.A., a cura di (2021). Psicopatologia della situazione. La psicoterapia della Gestalt nei campi clinici delle relazioni umane. Milano: FrancoAngeli. ISBN 978-88351-2031-5, pp. 344, € 35,00-Mortola P. (2022). Il metodo Oaklander. La psicoterapia della Gestalt attraverso il gioco. Milano: FrancoAngeli. ISBN 8835121671, pp. 236, € 29,00
Entrenamiento de redes neuronales recurrentes usando la dimensión de encaje en el espacio de las fases
Authors: Perugachi Cahueñas Nelly Patricia , Moreno Palacios Mariela Micaela , Haro Velasteguí Arquímides Xavier 
Published: August 2022

Se propone un método usando Redes Neuronales Recurrentes para la predicción de datos caóticos, aplicando la Teoría del Caos, para estudiar el comportamiento dinámico de los datos en el espacio multidimensional de las fases, establecer la correlación de los mismos y determinar la dimensión de encaje como base para el entrenamiento de las redes neuronales, así como determinar las características dinámicas del sistema calculando los coeficientes de Lyapunov y la entropía de Kolmorov-Siani, que nos indican el grado de desorden que tiene el sistema, para proyectar la precisión de la predicción. Se usan datos de contaminantes PM2.5 tomados en el centro Histórico de la ciudad de Quito, en intervalos de una hora, entre los años 2005 a 2019. Los resultados determinan que las series de datos corresponden a un sistema caótico (más de un coeficiente positivo de Lyapunov), por lo que se justifica la aplicación de la Teoría del Caos en el análisis de los mismos, dando buenos resultados en las predicciones aplicando los métodos de redes neuronales recurrentes de Elman y Jordan, al comparar las series predichas se demuestran que no presentan diferencias significativas entre ellas, ni con los datos medidos, usando el método de varianza con 0,05 de significancia, el error cuadrático porcentual respecto al rango de variación de los datos es aproximadamente del 5 % en ambos casos. Objetivos: Proponer un método que ayude al entrenamiento de las redes neuronales usando la Teoría del caos, mediante la implementación de la dimensión de encaje en el espacio de las fases.
Initial status and 3-month results relating to the use of biodegradable nitride iron stents in children and the evaluation of right ventricular function
Authors: Sun Ling , Li Jun-jie , Xu Yu-kai , Xie Yu-mei , Wang Shu-shui , Zhang Zhi-wei 
Published: August 2022

BackgroundPulmonary artery stenosis is often associated with congenital heart disease. The aim of the study was to evaluate the efficacy and safety of stenting for branch pulmonary artery stenosis using a biodegradable nitride iron stent (IBS® Angel™) and right ventricular systolic and diastolic function.MethodsFrom July 2021 to February 2022, a total of 11 cases (ages ranged from 36 to 86 months old) were included in this pre and post-intervention, prospective, cohort and preclinical study. All cases underwent transthoracic echocardiographic (TTE), chest radiography, along with computed tomography (256-slice scanner, multiple-detector) and right heart catheterization. Different types of biodegradable nitride iron stents were implanted. TTE was performed serially 1 day, 1 month and 3 months after the procedure to evaluate the rate of restenosis and right ventricular function.ResultsStenting was successful in 11 patients. There were no major adverse cardiovascular events related to the device or to the procedure. Blood perfusion in the branch pulmonary artery was improved immediately. At follow-up, there was no significant restenosis that required re-intervention. None of the patients suffered from in-stent thrombosis, vascular embolism, stent displacement or heart failure. Compared with normal values, there were statistical with regards to FAC, E/A and E′/A′. Furthermore, we found that TAPSE correlated significantly with pulsed Doppler S wave (p = 0.008) and left ventricular ejection fraction (p &lt; 0.01). The early trans-tricuspid inflow velocities E/E′ (tissue doppler at the lateral tricuspid annulus) correlated significantly with E′/A′ (p = 0.009). FAC and E′/A′ were statistically different from those prior to stenting (p = 0.041 and p = 0.035) when tested one month postoperatively. At three months postoperatively, only E/A showed a statistical difference (p = 0.015).ConclusionOur analysis suggests that biodegradable nitride iron stents are feasible, safe, and effective in children. Some small improvements were observed in right ventricular systolic and diastolic function after successful transcatheter intervention, although change was not statistically significant due to the small sample number. (A clinical Trial to Evaluate the Safety and Efficacy of IBS Angel in Patients With Pulmonary Artery Stenosis (IRIS); NCT04973540).
Reproductive factors and cognitive impairment in natural menopausal women: A cross-sectional study
Authors: Xi Haitao , Gan Jinghuan , Liu Shuai , Wang Fei , Chen Zhichao , Wang Xiao-Dan , Shi Zhihong , Ji Yong 
Published: August 2022

IntroductionLittle information on rural older women in northern China has been reported, apart from three studies in southern and eastern China in the past decade. This study aims to evaluate the relationships between reproductive factors and the risk of cognitive impairment, including mild cognitive impairment (MCI) and dementia, in Chinese women with natural menopause.MethodsThe cross-sectional study was conducted in 112 community primary healthcare centers in rural northern China between April 2019 and January 2020. A total of 4,275 women aged ≥65 years who had natural menopause were included. Reproductive factors as well as the reproductive period (= age at menopause − age at menarche) were recorded. The relationships between reproductive factors and cognitive impairment were evaluated by correlation and logistic regression analysis.ResultsOverall, 28.6% and 11.4% of women were diagnosed with MCI or dementia, respectively. In natural menopause women, the age at menopause (adjusted r = 0.070, p &lt; 0.001), reproductive period (adjusted r = 0.053, p = 0.001), and number of pregnancies (adjusted r = −0.042, p = 0.007) and parities (adjusted r = −0.068, p &lt; 0.001) were correlated with Mini-Mental State Examination (Chinese version) scores, and with similar findings concerning MCI and dementia with Lewy bodies (DLB). Greater age at menopause and a long reproductive period significantly decreased the risk of MCI and Alzheimer’s disease (AD), and more parities significantly increased the risks of MCI (odds ratio (OR) = 1.111, 95% confidence interval (CI): 1.039–1.187, p = 0.002), dementia (OR = 1.162, 95% CI: 1.061–1.271, p = 0.001), particular AD (OR = 1.131, 95% CI: 1.010–1.266, p = 0.032), DLB (OR = 1.238, 95% CI: 1.003–1.528, p = 0.047), and vascular dementia (VaD) (OR = 1.288, 95% CI: 1.080–1.536, p = 0.005).ConclusionsThe prevalence rates of MCI and dementia were 28.6% and 11.4% in older women. Greater age at menarche, young age at menopause, shorter reproductive period, and larger numbers of pregnancies/parities were correlated with poor cognition and significantly increased the risks of MCI and dementia, particularly AD, DLB, and VaD.