bluuebunny/crossref_metadata_2025_split huggingface dataset:
La contraception dans Femmes d’Aujourd’hui (1960-2010) : entre visibilisation
et assignation de genre du travail procréatif
Authors: Roberti-Lintermans Margaux 
Published: March 2022

Cadre de la recherche : Femmes d’Aujourd’hui, premier magazine féminin
francophone belge, s’adresse majoritairement à un lectorat féminin et transmet
un discours sur la contraception, tout en contribuant à sa construction.
Objectifs : Nous analysons ce discours
dans une perspective chronologique longue (1960-2010) au regard des
transformations sociétales et législatives en Belgique. Comment la régulation
des naissances est-elle présentée ? À qui incombe cette responsabilité ? Comment
se transmet-elle ?
Méthodologie : À partir d’une analyse
qualitative basée sur un dépouillement systématique de la revue, nous rendons
compte de l’évolution du discours sur la contraception.
Résultats : Dimension fondamentale du
travail procréatif, la contraception est initialement défendue comme une
responsabilité partagée au sein du couple, conformément à l’orientation
chrétienne de la revue et de ses journalistes. Par la suite, la régulation des
naissances devient progressivement une tâche exclusivement féminine, les
différents contraceptifs portés sur les corps des femmes étant alors classés
selon des critères d’efficacité mis en avant par le corps médical. Au tournant
des années 2000, l’information sur les moyens de contraception se diversifie et
laisse place aux critiques dans le courrier des lectrices.
Conclusions : Visibilisant les
différentes méthodes dans un objectif qui se veut informatif avant tout, Femmes d’Aujourd’hui fait pourtant la promotion d’une
norme contraceptive et procréative. Grâce aux méthodes contraceptives, la
maternité peut être accomplie en respect de normes sociales, prescrivant
notamment une certaine trame temporelle, où le type de contraceptif change en
fonction du projet d’enfant. Enfin, bien qu’elle laisse place au débat via les lectrices ou les journalistes, la presse
féminine contribue paradoxalement à l’assignation genrée du contrôle des
naissances.
Contribution : Le discours sur la
contraception dans Femmes d’Aujourd’hui contribue à
diffuser une injonction à la maternité. Nous identifions dans notre recherche
des normes procréatives contribuant à cela. Celles-ci évoluent en deux phases
liées au contexte sociétal et législatif.
Reimagining Design
Authors: Bethune Kevin G. 
Published: March 2022

The power of transformative design, multidisciplinary leaps, and diversity: lessons from a Black professional's journey through corporate America.
Design offers so much more than an aesthetically pleasing logo or banner, a beautification add-on after the heavy lifting. In Reimagining Design, Kevin Bethune shows how design provides a unique angle on problem-solving—how it can be leveraged strategically to cultivate innovation and anchor multidisciplinary teamwork. As he does so, he describes his journey as a Black professional through corporate America, revealing the power of transformative design, multidisciplinary leaps, and diversity. Bethune, who began as an engineer at Westinghouse, moved on to Nike (where he designed Air Jordans), and now works as a sought-after consultant on design and innovation, shows how design can transform both individual lives and organizations.
In Bethune's account, diversity, equity, and inclusion emerge as a recurring theme. He shows how, as we leverage design for innovation, we also need to consider the broader ecological implications of our decisions and acknowledge the threads of systemic injustice in order to realize positive change. His book is for anyone who has felt like the “other”—and also for allies who want to encourage anti-racist, anti-sexist, and anti-ageist behaviors in the workplace. Design transformation takes leadership—leaders who do not act as gatekeepers but, with agility and nimbleness, build teams that mirror the marketplace.
Design in harmony with other disciplines can be incredibly powerful; multidisciplinary team collaboration is the foundation of future innovation. With insight and compassion, Bethune provides a framework for bringing this about.
The repurposing of Tebipenem pivoxil as alternative therapy for severe gastrointestinal infections caused by extensively drug-resistant Shigella spp
Authors: Fernández Álvaro Elena , Voong Vinh Phat , de Cozar Cristina , Willé David R , Urones Beatriz , Cortés Alvaro , Price Alan , Tran Do Hoang Nhu , Ha Thanh Tuyen , McCloskey Molly , Shaheen Shareef , Dayao Denise , Martinot Amanda , de Mercado Jaime , Castañeda Pablo , García-Perez Adolfo , Singa Benson , Pavlinac Patricia , Walson Judd , Martínez-Martínez Maria Santos , Arnold Samuel LM , Tzipori Saul , Ballell Pages Lluis , Baker Stephen 
Published: March 2022

Background:Diarrhoea remains one of the leading causes of childhood mortality globally. Recent epidemiological studies conducted in low-middle income countries (LMICs) identified Shigella spp. as the first and second most predominant agent of dysentery and moderate diarrhoea, respectively. Antimicrobial therapy is often necessary for Shigella infections; however, we are reaching a crisis point with efficacious antimicrobials. The rapid emergence of resistance against existing antimicrobials in Shigella spp. poses a serious global health problem.Methods:Aiming to identify alternative antimicrobial chemicals with activity against antimicrobial resistant Shigella, we initiated a collaborative academia-industry drug discovery project, applying high-throughput phenotypic screening across broad chemical diversity and followed a lead compound through in vitro and in vivo characterisation.Results:We identified several known antimicrobial compound classes with antibacterial activity against Shigella. These compounds included the oral carbapenem Tebipenem, which was found to be highly potent against broadly susceptible Shigella and contemporary MDR variants for which we perform detailed pre-clinical testing. Additional in vitro screening demonstrated that Tebipenem had activity against a wide range of other non-Shigella enteric bacteria. Cognisant of the risk for the development of resistance against monotherapy, we identified synergistic behaviour of two different drug combinations incorporating Tebipenem. We found the orally bioavailable prodrug (Tebipenem pivoxil) had ideal pharmacokinetic properties for treating enteric pathogens and was effective in clearing the gut of infecting organisms when administered to Shigella-infected mice and gnotobiotic piglets.Conclusions:Our data highlight the emerging antimicrobial resistance crisis and shows that Tebipenem pivoxil (licenced for paediatric respiratory tract infections in Japan) should be accelerated into human trials and could be repurposed as an effective treatment for severe diarrhoea caused by MDR Shigella and other enteric pathogens in LMICs.Funding:Tres Cantos Open Lab Foundation (projects TC239 and TC246), the Bill and Melinda Gates Foundation (grant OPP1172483) and Wellcome (215515/Z/19/Z).
Improving the Quality of Fast Pyrolysis Bio-oil (Liquid Fuel) using Thermal Distillation Method
Authors: Haqbin Masoud , Rezazada Farid Ahmad , Qarizada Kongul , Dadwar Malalay , Kambakhsh Hamasa , Qarizada Deana 
Published: March 2022

Oil palm biomass generates an abundance via the oil palm industry such as Palm kernel shell (PKS), empty fruit bunch (EFB), frond, trunk.
Problem Statement: The main issue nowadays is global warming; one of the factors is the increment of CO2 content in the atmosphere. In order to reduce the CO2 content in the atmosphere, biomass is used, as it is a renewable, sustainable, and cost-effective alternative energy source that needs to be adopted in the energy mix. The objective of this study was to improve the quality of bio-oil.
Approach: In this research, an empty fruit bunch (EFB) was utilized in a fixed bed reactor, and pyrolysis oil was upgraded via a thermal distillation reactor. The temperature of pyrolysis was 500 °C, and the temperature of thermal distillation was 100 °C. Gas chromatography-mass spectroscopic and ultimate analysis was utilized to investigate chemical composition.
Results: The maximum distilled bio-oil yield was 60- 65 % at 100 °C. The heating value of bio-oil was 21 MJ/kg, and distilled bio-oil was 30 MJ/kg. The density of bio-oil was 1035 g/mL, and distilled bio-oil was 980 g/mL
Conclusion: The results showed that the distilled bio-oil obtained from EFB bio-oil has a high heating value low oxygen content than it can use as fuel in engines.
Boronate Affinity Chromatography
Authors: Liu Zhen , Li Hengye , Muhammad Pir 
Published: March 2022

Abstract

Boronate affinity chromatography (BAC) is a unique mode of affinity chromatography. It relies on the pH‐dependent, covalent and reversible interactions between boronic acid ligands and
cis
‐diol‐containing compounds. This chemistry endows BAC with the unique capability for selective recognition, capture, isolation, and enrichment of
cis
‐diol‐containing biomolecules.
Cis
‐diol‐containing biomolecules are an important class of compounds, including catecholamines, saccharides, ribonucleosides, ribonucleotides, glycopeptides and glycoproteins. These biomolecules play essential roles in many life‐related processes, and many of them are important target molecules in current research frontiers, such as proteomics, metabolomics, and glycomics. In recent decades, BAC and boronate affinity materials (BAMs) have developed rapidly and found promising applications in multiple areas. This article provides a review for general readers, covering from the very beginning of this technique to its recent development. We mainly focus on fundamental considerations, major progresses, and new BAMs reported in recent decades. In addition, prospects for the future development and application of BAC are discussed.
A Dendritic Polymer‐Based Nanosystem Mediates Drug Penetration and Irreversible Endoplasmic Reticulum Stresses in Tumor via Neighboring Effect
Authors: Zheng Xiuli , Pan Dayi , Zhu Guonian , Zhang Lu , Bhamra Apanpreet , Chen Rongjun , Zhang Hu , Gong Qiyong , Gu Zhongwei , Luo Kui 
Published: March 2022

AbstractNanoparticles (NPs)‐based cancer therapeutics are generally impeded by poor drug penetration into solid tumors due to their dense tumor extracellular matrix (ECM). Herein, pH/redox‐responsive dendritic polymer‐based NPs are developed to amplify the neighboring effect for improving drug penetration and driving cell apoptosis via combination therapy. Pyropheophorbide a (Ppa) is conjugated with PEGylated dendritic peptides via disulfide bonds and doxorubicin (DOX) encapsulated in the conjugate to construct dual‐responsive NPs, PDPP@D. Delayed released DOX and Ppa from PDPP@D exert their combination therapeutic effect to induce cell apoptosis, and then they are liberated out of dying cells to amplify the neighboring effect, resulting in their diffusion through the dense ECM and penetration into solid tumors. Transcriptome studies reveal that PDPP@D leads to irreversible stress on the endoplasmic reticulum and inhibits cell protection through blocking the IRE1‐dependent survival pathway and unleashing the DR5‐mediated caspase activity to promote cell death. The strategy of amplifying the neighboring effect of NPs through combination therapy may offer great potential in enhancing drug penetration and eradicating solid tumors.
Rapid Stem Cell Extraction and Culture Device for Regenerative Therapy Using Biodegradable Nonwoven Fabrics with Strongly Oriented Fibers
Authors: Sunami Hiroshi , Shimizu Yusuke , Futenma Naoko , Denda Junko , Nakasone Hitoshi , Yokota Sayaka , Kishimoto Hidehiro , Makita Masashi , Nishikawa Yasutoshi 
Published: March 2022

AbstractBiodegradable nonwoven fabrics that can be used to extract and culture adipose‐derived stem cells (ADSCs) from adipose tissue slices without enzyme digestion are developed. The fabrics are made of fibers consisting of biodegradable poly(lactic‐co‐glycolic acid) (PLGA) and hydroxyapatite (HAp), which can be strongly oriented by adjusting the fiber deposition conditions. ADSCs are extracted from adipose tissue slices and cultured, and thick cell sheets are produced by placing nonwoven fabric on the adipose tissue slices or sandwiching the adipose tissue slices between two layers of fabric. Nonwoven fabrics with large anisotropy extract and culture ADSCs from adipose tissue slices more quickly than those with small anisotropy. In addition, cell sheets are produced more rapidly by cultivating cells on a culture vessel with low‐cell adhesion. Finally, it confirms that ADSCs extracted and cultured from adipose tissue slices using nonwoven fabrics maintain the characteristics of mesenchymal stem cells.
In‐Depth Investigation of Inkjet‐Printed Silver Electrodes over Large‐Area: Ink Recipe, Flow, and Solidification
Authors: Zhou Lu , Chen Xiaolian , Su Wenming , Cui Zheng , Lai Wen‐Yong 
Published: March 2022

AbstractInkjet‐printed flexible transparent conducting electrodes (TCEs) have attracted much recent interest in realizing large‐scale and high‐volume fabrication required by the industrial production protocol. In this paper, an in‐depth investigation and optimization of template‐less inkjet printing for the metal meshes based TCEs are presented. The general principle of conductive ink formulation for inkjet printing, the droplet coalescence and crawling on the substrates, and its solidification processes are thoroughly studied. Ideal silver lines with high conductivity of 3.4  µΩ · cm can be obtained on various substrates, with fine line‐width adjustment by step length of 5 µm. The uniformity of the width, morphology, and conductivity of printed silver lines over large‐area are improved by factors of 3.44, 1.53, and 1.95, respectively. Subsequently, passive matrix organic light emitting diodes based on silver array electrodes are fabricated to successfully light the point, line, and surface. A flexible silver mesh TCE is also printed, with low sheet resistance of 9.56 Ω sq−1 and good flexibility.
Tunable Adhesion and Interfacial Structure of Layer‐by‐Layer Assembled Block co‐polymer Micelle and Polyelectrolyte Coatings
Authors: Reid Michael S. , Träger Andrea , Cobo Sanchez Carmen , Malmström Eva , Wågberg Lars 
Published: March 2022

AbstractUnderstanding and tuning nanoscale structure is critical in developing new coatings and adhesives. In this work layer‐by‐layer assembly of block co‐polymer (BCP) micelles and oppositely charged polyelectrolytes produces structurally unique coatings with wet adhesion comparable to that of mussel adhesive proteins. Cationic (CAT) and anionic (ANI) BCPs, synthesized by atom transfer radical polymerization (ATRP), are used to create colloidally stable, self‐assembled, spherical BCP micelles. The assembly of BCP micelle and polyelectrolyte multilayers is monitored in situ where CAT‐ and ANI‐BCP micelles exhibit linear and super‐linear growth, respectively. Imaging of the surfaces reveals that CAT‐BCP micelles yield flat, uniform layers whereas ANI‐BCP micelle assemblies form islands that increase in surface area with each additional layer. The adhesion of these layers, measured by colloidal probe atomic force microscopy (CP‐AFM), shows that the distinct layers of CAT‐BCP micelle assemblies produce alternating high and low adhesion surfaces whereas ANI‐BCP micelle assemblies continually increase in adhesion with each additional bilayer. The unique behavior of each assembly demonstrates that both composition and structure play important roles in wet adhesion of submicron layers and that each can be tuned to target performance for different applications.
Mechanism of Spin‐Orbit Torques in Platinum Oxide Systems
Authors: Nath Jayshankar , Trifu Alexandru Vladimir , Gabor Mihai Sebastian , Hallal Ali , Auffret Stephane , Labau Sebastien , Mahjoub Aymen , Chan Edmond , Chaurasiya Avinash Kumar , Mondal Amrit Kumar , Yang Haozhe , Schmoranzerova Eva , Nsibi Mohamed Ali , Joumard Isabelle , Barman Anjan , Pelissier Bernard , Chshiev Mairbek , Gaudin Gilles , Miron Ioan Mihai 
Published: March 2022

AbstractSpin‐Orbit Torque (SOT) Magnetic Random‐Access Memories (MRAM) have shown promising results toward the realization of fast, non‐volatile memory systems. Oxidation of the heavy‐metal (HM) layer of the SOT‐MRAM has been proposed as a method to increase its energy efficiency. But the results are widely divergent due to the difficulty in controlling the HM oxidation because of its low enthalpy of formation. Here, these differences are reconciled by performing a gradual oxidation procedure, which allows correlating the chemical structure to the physical properties of the stack. As an HM layer, Pt is chosen because of the strong SOT and the low enthalpy of formation of its oxides. The evidence of an oxide inversion layer at the ferromagnet (FM)/HM interface is found: the oxygen is drawn into the FM, while the HM remains metallic near the interface. Moreover, the oxygen migrates in the volume of the FM layer rather than being concentrated at the interface. Consequently, it is found that the intrinsic magnitude of the SOT is unchanged compared to the fully metallic structure. The previously reported apparent increase of SOTs is not intrinsic to platinum oxide and instead arises from systemic changes produced by oxidation.
Comparing mechanical harvest with alternative ground‐based methods for estimating forage yields in cool‐season annual grasses
Authors: Simoneaux Bryan , Neely Clark , Ibrahim Amir M.H. , Rajan Nithya , Popescu Sorin 
Published: March 2022

AbstractTo accurately estimate forage yield of experimental lines and cultivars without the time and expense of harvesting with and maintaining a plot harvester would aid cool‐season forage grass researchers and breeders in cultivarselection and advancement. A cool‐season annual grass forage trial was conducted at the Texas A&M Research Farm during the 2015–2016 and 2016–2017 growing seasons. The trial included commercial and experimental small grains and ryegrass cultivars that include wheat (Triticum aestivum L.), rye (Secale cereale L.), oat (Avena sativa L.), triticale (Triticum secale), barley (Hordeum vulgare L.), and annual ryegrass (Lolium multiflorum Lam.). The trial was set up in a randomized complete block design (RCBD) with four replications of 37 entries in 2016 and 38 in 2017. Visual rating (VR), plant height (HT), and sample weights were collected. The objective of this research was to compare mechanically harvested aboveground biomass yield of a multiple species cool‐season annual grasses with limited or nondestructive measurements to estimate plot yield. The VR evaluation was most successful in the fall (r = .84, p < .001) compared to other measurement dates. Plant height had the highest correlation to yield in the fall (r = .81, p < .001) across species, but when combined across species and measurement date it decreased to r = .15 (p < .001). Subsampling would be the only acceptable method for comparisons of entries across measurement dates, species, and years with an r = .83 (p < .001). While subsampling provided a reliable correlation, combining all measurements into one model improved forage yield prediction as an alternative to mechanical whole plot forage harvest.
Dense non‐Newtonian suspension flow: Effect of solids properties and pipe size
Authors: Zheng Enzu , Rudman Murray , Kuang Shibo , Chryss Andrew 
Published: March 2022

AbstractHigh concentration tailings transport is a promising approach for improving the safety and environmental impact of mining tailings disposal. High concentration suspensions exhibit complex non‐Newtonian behavior. The interaction between the non‐Newtonian carrier and the coarse particles is still poorly understood, particularly in the turbulent regime. This article considers the effect of solids concentration, particle and pipe size on transport characteristics in a weakly turbulent non‐Newtonian suspension using a DNS‐DEM methodology. Heterogeneous flow and a sliding bed are presented in the turbulent regime, with particles being more suspended in a small pipe. Although stratification is observed, there is no “packed” bed predicted for these cases. The presence of the viscous core region contributes to the dominance of the drag force in the central region in a non‐Newtonian suspension. Non‐Newtonian suspensions can also be transported at a much lower velocity and display a comparable specific energy consumption to a conventional dilute suspension.
Evolution and conservation genetics of an insular hemiparasitic plant lineage at the limit of survival: the case of Thesium sect. Kunkeliella in the Canary Islands
Authors: Rodríguez‐Rodríguez Priscila , Fernández de Castro Alejandro G. , Pérez de Paz Pedro Luis , Curbelo Leticia , Palomares Ángel , Mesa Ricardo , Acevedo Aurelio , Sosa Pedro A. 
Published: March 2022

AbstractPremiseThe diversification of island flora has been widely studied. However, the role of environmental niches in insular radiation processes has been less investigated. We combined population genetic analyses with species distribution modelling to clarify the genetic relationships, diversification patterns, species niche requirements, and conservation of Thesium sect. Kunkeliella, a clade of rare hemiparasitic plants endemic to the Canaries.MethodsWe studied the three extant Thesium species and a new taxon from La Palma Island. We developed 12 microsatellites and performed population genetic analysis and studied the demographic history of the group. To evaluate the role of niche conservatism in the diversification of the group, we performed species distribution modelling (ESM) with four algorithms.ResultsAll species presented moderate genetic diversity values for rare endemics. Thesium canariense (Gran Canaria) showed high differentiation, whereas T. subsucculentum, T. retamoides (Tenerife), and La Palma populations are closely related. The lineage may have undergone a recent diversification with colonization proceeding east to west, with T. canariense as sister to the others. We detected a climatic niche shift, as taxa showed different distributions across the temperature gradient. There is enough evidence to describe La Palma populations as a new species.ConclusionsWe characterized the evolutionary history of Thesium sect. Kunkeliella by integrating genetic and ecological assessments. Our results indicate that this clade has undergone a recent radiation process with niche differentiation among species. The results increase our knowledge about insular radiations and will inform the conservation management of the study species.
Novel phenotypic feature in a patient with a recurrent NOTCH2 nonsense mutation
Authors: Tan Ene‐Choo , Lai Angeline H. M. , Brett Maggie S. Y. 
Published: March 2022

AbstractPathogenic variants in NOTCH2 which encodes a single‐pass transmembrane protein have been identified as a cause of several autosomal dominant congenital disorders. In particular, truncating mutations in exon 34 have been found in patients with skeletal abnormalities and dysmorphic features. We describe a patient with a de novo variant in NOTCH2 who displayed features of both Hajdu–Cheney syndrome (HJCYS) and serpentine fibula‐polycystic kidney syndrome (SFPKS). The recurrent nonsense variant in exon 34 has been reported in seven other patients with syndromic presentations, making it the most common pathogenic variant for NOTCH2 in congenital disorders. In addition to the core features of HJCYS and SFPKS, there was a gastrointestinal tract malformation of an imperforate anus which has not been reported in patients with pathogenic variants in NOTCH2.