bluuebunny/crossref_metadata_2025_split huggingface dataset:
Doktor Faustus and its Variations on Lateness
Authors: Cai Cecily 
Published: November 2022

Abstract
Thomas Mann’s novel Doktor Faustus, first published 1947, tells the story of a fictional German musician, Adrian Leverkühn, paralleled with the rise and fall of Germany in the first half of the 20th century. In fact, the idea of Doktor Faustus predated Mann’s exile, and it had been already conceived as a work of lateness – a Faust, a Parsifal in prose. In the process of creating variations on lateness, Mann referred to the musical models of Beethoven, Wagner, Mahler, Schoenberg, and the music criticism of Theodor W. Adorno. As a product of Mann’s exile in Southern California, Doktor Faustus connects the concept of lateness with his experience of exile through music, as Edward Said would later point out in his reflections on “late style.” By engaging with pre-existing compositions and criticism, I will present Doktor Faustus as a novelistic rendering of musical lateness that not only engages with compositions such as Wagner’s Parsifal and Mahler’s Ninth Symphony but also sheds new light on the interpretation of lateness as an artistic and – above all – human experience.
When Translation Reshapes Reception: The Curious Case of Zeruya Shalev in the German Literary Sphere of World Literature
Authors: Kellner Tom 
Published: November 2022

Abstract
This article sets out to explore the conditions that paved the way for the unique success of the German translation of Zeruya Shalev’s second novel, Love Life (Hayei ahava, 1997), offering a specific example of the potential benefits that arise from cross-cultural translations. Upon its publication in Israel, Love Life was received quite critically; it was considered too simplistic, straightforward, and feminine to be considered an ‘important’ work. However, following the novel’s translation into German by Mirjam Pressler in 2000, it gained wide recognition in Germany and soon became a best-seller, owing much to Marcel Reich-Ranicki’s unusually warm review on the television program Das literarische Quartett (The Literary Quartet). Hence, this article examines the various cultural and commercial conditions that set the backdrop for Love Life’s success as a translated work. While focusing on the reception of a specific literary text, the article surveys both Israeli and German literary spheres, and draws on the contemporary discourse in the field of World Literature. Furthermore, it offers a comprehensive discussion on translation, and demonstrates the unique position of translated literature, and specifically Hebrew literature, in the German literary field. Subsequently, the discussion sheds light not only on the circumstances that supported, if not determined, Love Life’s enthusiastic reception in Germany, but also on the extraordinary effect of this success on Shalev’s position within the Israeli literary system in the two decades that have followed.
Private Benefits of Control and the Core
Authors: Lee Kyounghun , Oh Frederick Dongchuhl 
Published: November 2022

Abstract
This study aims to analyze the core in production economies with private benefits of control. We consider two types of shareholders in a firm: small shareholders and the controlling shareholder. Unlike small shareholders, the controlling shareholder’s utility increases not only with the consumption of goods but also with private benefits related to the production level of the firm and his controlling power. We observe that the private benefits of control are allowed in the core only when the transferred utility from the controlling shareholder to small shareholders is higher than the small shareholders’ utility loss from private benefits.
Differences in clinical reasoning between female and male medical students
Authors: Hege Inga , Hiedl Meike , Huth Karin Christine , Kiesewetter Jan 
Published: November 2022

Abstract

Objectives
In undergraduate medical education virtual patients (VPs) are a suitable method to teach clinical reasoning and support the visualization of this thinking process in a safe environment. The aim of our study was to investigate differences in the clinical reasoning process and diagnostic accuracy of female and male medical students.

Methods
During the summer term 2020, we provided access to 15 VPs for undergraduate students enrolled in a medical school in Bavaria, Germany. All interactions of the 179 learners within the VP system CASUS were recorded, exported, and analyzed.

Results
We found significant differences in the clinical reasoning of female and male learners. Female students documented more findings, differential diagnoses, tests, and treatment options and more often created a summary statement about the VP. Their overall performance was higher than those of their male peers, but we did not see any significant differences in diagnostic accuracy.

Conclusions
The significant differences between male and female medical students should be considered when planning teaching and research activities. A future study should investigate whether these differences can also be found in physicians.
Preparation of Na2HPO4⋅12H2O-based composite PCM and its application in air insulated box
Authors: Zheng Maosheng , Li Yuebei , Peng Xiaojian , Zhang Shuai 
Published: November 2022

Abstract
In order to provide continuous supply for succeeding application, abundant electricity energy and solar energy can be stored by means of thermal storage technology. In the present paper, the heat energy storage/exothermic tests are conducted to evaluate the performance of thermal energy storage and release of electricity energy in the self – designed heat storage box equipped with the composite phase change material (PCM), the delivery of heat to surrounding environment is through an air blower directly. The composite PCM consisting of Na2HPO4⋅12H2O and Na3PO4⋅12H2O at the ratio of 7:3 is used to carry out the tests, which is with stable solidification property. Following results are obtained from this research: (1) The solidification temperature of the composite PCM is 33.4 °C with reduced supercooling degree of 2.6 °C; (2) The is phase change exothermic enthalpy value of the composite PCM is 178.02 J/g; (3) The self – designed “peak load shifting” heat storage equipment for electricity energy is with the energy exchange efficiency of 89.59%. The achievements of this research show the applicability of the thermal storage technology by means of the composite PCM.
Amino acid profiles in the tissue and serum of patients with liver cancer
Authors: Liu Da-Hua , Wen Gui-Min , Song Chang-Liang , Ji Li-Jun , Xia Pu 
Published: November 2022

Abstract
Most patients with liver cancer were found late and lost the chance of surgery. Liquid biopsy can monitor the risk of tumor recurrence and metastasis, quickly evaluate the curative effect of tumor treatment, and is conducive to early screening and auxiliary diagnosis of high-risk groups. Amino acid (AA) profiling has been used to the diagnosis and the prognosis for cancers. However, little was known about the profiles of AA of liver cancer. In this study, we used tRNA in Cancer database to analyze the AA levels in liver cancer tissues. Blood samples of patients with liver cancer were collected and analyzed using the automatic AA analyzer. We found that valine, isoleucine, and leucine were decreased significantly both in the plasma and the tumor tissues of patients with liver cancer. However, upregulation of methionine was observed in tissues and plasma of patients with liver cancer. Interestingly, tyrosine, and phenylalanine were decreased in tumor tissue but increased in the plasma of patients with liver cancer. This is the first report provided an overview of AA profile in both plasma and tissue for patients with liver cancer. AA levels can be used as diagnostic and prognostic markers of patients with liver cancer.
Crystal structure of propane-1,3-diylbis(diphenylphosphine sulfide) ethanol solvate, C27H26P2S2
Authors: Tapala Kgaugelo C. , Clayton Hadley S. 
Published: November 2022

Abstract
C27H26P2S2, tetragonal, I4 (no. 79), a = 16.9196(12) Å, c = 9.4187(8) Å, V = 2696.3(4) Å3, Z = 4, R
gt(F) = 0.0341, wR
ref(F
2) = 0.0726, T = 173(2) K.
Crystal structure of 14-O-acetyldelcosine, C26H41NO8
Authors: Liu Huan-Ni , Hao Yi-Kun , Chen Neng-Hua , Li Lai-Ming 
Published: November 2022

Abstract
C26H41NO8, orthorhombic, P212121 (no. 19), a = 8.24370(10) Å, b = 13.1867(2) Å, c = 22.8490(4) Å, V = 2483.85(6) Å3, Z = 4, Rgt
(F) = 0.0357, wRref
(F
2) = 0.0975, T = 169.99(10) K.
Study of concrete properties based on crushed stone sand mixture and fiber of fly ash of thermal power plants
Authors: Bieliatynskyi Andrii , Yang Shilin , Pershakov Valerii , Shao Meiyu , Ta Mingyang 
Published: November 2022

Abstract
The study aims to optimize the composition of the main composite, the components of which, in their joint presence, make it possible to obtain the most significant positive synergistic effect. The authors of this article used the fibers of fly ash from thermal power plants as a finely dispersed component added to the crushed stone sand mixture. The result of the study was a high-strength corrosion-resistant material consisting of a crushed stone sand mixture (CSSM) with the addition of the fibers of fly ash. The authors applied the thermogravimetric and standard methods to study and determine the performance and strength characteristics of the obtained material. The combined effect of a complex organic-mineral modifying additive and the cement with the fibers of fly ash provided a compacted and reinforced structure of cement stone. An optimal binder composition was developed, consisting of cement and fiber of fly ash. The authors of this article examined the physical-mechanical and structural-mechanical properties of a CSSM of fine-grained concrete reinforced with a complex additive of cement, fibers of fly ash, and a superplasticizer. The study also provided technological solutions for manufacturing a functional mixture of fine-grained concrete based on the developed complex organic-mineral additive.
A novel synthesis of graphene oxide-titanium dioxide (GO-TiO2) and graphene oxide-zinc oxide (GO-ZnO) nanocomposites and their application as effective, reusable photocatalysts for degradation of methylene blue (MB) dye
Authors: Kumari Sujata , Sharma Pratibha , Ghosh Debasree , Das Anirban , Kaushal Akshey , Rawat Pooja , Sinha Chittaranjan , Bhattacharya Jaydeep , Srivastava Chandra Mohan , Majumder Sudip 
Published: November 2022

Abstract
The current study focuses on graphene oxide (GO) and its composite with zinc oxide and titanium dioxide nanoparticles to develop a simple nano chemistry-based clean and efficient process for the effective degradation of methylene blue (MB) dye. Graphene oxide composite with zinc oxide and titanium dioxide nanoparticles were fabricated via a thermal coupling process that demonstrates exclusive physiochemical properties. A detailed comparison of the structure, morphology, and surface analysis of synthesized GO and nanocomposites, as well as their electrochemical properties, has been accomplished. By using the degradation of methylene blue (MB) dye the photocatalytic function of nanocomposites was studied. Results reveal that the rate constants of GO, GO-TiO2, and GO-ZnO photocatalysts are 1.06 × 10−3 min−1, 2.56 × 10−3 min−1, and 1.63 × 10−3 min−1 respectively which discloses GO-TiO2 nanocomposite shows maximum degradation of MB dye among both catalysts. The reuse of photocatalyst even after five cycles retained the degradation efficiency of 80, 77, and 49% respectively for GO-TiO2, GO-ZnO, and GO when tested against MB. Hence, as a result, it was determined that these photocatalysts are ideal for the remediation of dye-contaminated wastewater.
Creation of Neuronal Ensembles and Cell-Specific Homeostatic Plasticity through Chronic Sparse Optogenetic Stimulation
Authors: Liu Benjamin , Seay Michael J. , Buonomano Dean V. 
Published: November 2022

Cortical computations emerge from the dynamics of neurons embedded in complex cortical circuits. Within these circuits, neuronal ensembles, which represent subnetworks with shared functional connectivity, emerge in an experience-dependent manner. Here we induced ensembles inex vivocortical circuits from mice of either sex by differentially activating subpopulations through chronic optogenetic stimulation. We observed a decrease in voltage correlation, and importantly a synaptic decoupling between the stimulated and nonstimulated populations. We also observed a decrease in firing rate during Up-states in the stimulated population. These ensemble-specific changes were accompanied by decreases in intrinsic excitability in the stimulated population, and a decrease in connectivity between stimulated and nonstimulated pyramidal neurons. By incorporating the empirically observed changes in intrinsic excitability and connectivity into a spiking neural network model, we were able to demonstrate that changes in both intrinsic excitability and connectivity accounted for the decreased firing rate, but only changes in connectivity accounted for the observed decorrelation. Our findings help ascertain the mechanisms underlying the ability of chronic patterned stimulation to create ensembles within cortical circuits and, importantly, show that while Up-states are a global network-wide phenomenon, functionally distinct ensembles can preserve their identity during Up-states through differential firing rates and correlations.SIGNIFICANCE STATEMENTThe connectivity and activity patterns of local cortical circuits are shaped by experience. This experience-dependent reorganization of cortical circuits is driven by complex interactions between different local learning rules, external input, and reciprocal feedback between many distinct brain areas. Here we used anex vivoapproach to demonstrate how simple forms of chronic external stimulation can shape local cortical circuits in terms of their correlated activity and functional connectivity. The absence of feedback between different brain areas and full control of external input allowed for a tractable system to study the underlying mechanisms and development of a computational model. Results show that differential stimulation of subpopulations of neurons significantly reshapes cortical circuits and forms subnetworks referred to as neuronal ensembles.
Microcircuit Synchronization and Heavy-Tailed Synaptic Weight Distribution Augment preBötzinger Complex Bursting Dynamics
Authors: Ashhad Sufyan , Slepukhin Valentin M. , Feldman Jack L. , Levine Alex J. 
Published: November 2022

The preBötzinger Complex (preBötC) encodes inspiratory time as rhythmic bursts of activity underlying each breath. Spike synchronization throughout a sparsely connected preBötC microcircuit initiates bursts that ultimately drive the inspiratory motor patterns. Using minimal microcircuit models to explore burst initiation dynamics, we examined the variability in probability and latency to burst following exogenous stimulation of a small subset of neurons, mimicking experiments. Among various physiologically plausible graphs of 1000 excitatory neurons constructed using experimentally determined synaptic and connectivity parameters, directed Erdős-Rényi graphs with a broad (lognormal) distribution of synaptic weights best captured the experimentally observed dynamics. preBötC synchronization leading to bursts was regulated by the efferent connectivity of spiking neurons that are optimally tuned to amplify modest preinspiratory activity through input convergence. Using graph-theoretic and machine learning-based analyses, we found that input convergence of efferent connectivity at the next-nearest neighbor order was a strong predictor of incipient synchronization. Our analyses revealed a crucial role of synaptic heterogeneity in imparting exceptionally robust yet flexible preBötC attractor dynamics. Given the pervasiveness of lognormally distributed synaptic strengths throughout the nervous system, we postulate that these mechanisms represent a ubiquitous template for temporal processing and decision-making computational motifs.SIGNIFICANCE STATEMENTMammalian breathing is robust, virtually continuous throughout life, yet is inherently labile: to adapt to rapid metabolic shifts (e.g., fleeing a predator or chasing prey); for airway reflexes; and to enable nonventilatory behaviors (e.g., vocalization, breathholding, laughing). Canonical theoretical frameworks—based on pacemakers and intrinsic bursting—cannot account for the observed robustness and flexibility of the preBötzinger Complex rhythm. Experiments reveal that network synchronization is the key to initiate inspiratory bursts in each breathing cycle. We investigated preBötC synchronization dynamics using network models constructed with experimentally determined neuronal and synaptic parameters. We discovered that a fat-tailed (non-Gaussian) synaptic weight distribution—a manifestation of synaptic heterogeneity—augments neuronal synchronization and attractor dynamics in this vital rhythmogenic network, contributing to its extraordinary reliability and responsiveness.
Az Ephedrae herba helye a nyugati orvoslásban
Authors: László Andrea , Béni Szabolcs , Nemcsik János 
Published: November 2022

Összefoglaló. A Magyar és az Európai Hypertonia Társaság legújabb
ajánlásában a gyógyszer okozta szekunder hypertoniák gyakoribb okai között
szerepel az Ephedra – csikófark (kínai nevén Mahuang) fajok
drogjának (Ephedrae herba) felhasználása is. Összefoglaló
közleményünk célja az Ephedra nemzetségbe tartozó, a
gyógyászatban is felhasznált, a VIII. Magyar Gyógyszerkönyvben és a Kínai
Gyógyszerkönyvben szereplő hivatalos fajoknak a részletes bemutatása.
Betekintést nyújtunk történetükbe, továbbá leírjuk a bennük található vegyületek
farmakológiai tulajdonságait és azok hatásait. Ismertetjük előnyeiket,
mellékhatásaikat és lehetséges gyógyszerkölcsönhatásaikat. Ezenkívül feltárjuk
fogyasztó- és testsúlycsökkentő szerként való használatukat,
étrend-kiegészítőként történő alkalmazásuk betiltásának okát, valamint
tárgyaljuk a doppinglistán való szereplésük magyarázatát is. Ezzel párhuzamosan
kitérünk az Ephedra fajok orvosi gyakorlatban betöltött
szerepére is: rendeltetésszerű használatuk során a fitoterápiában – főleg
kombinációban alkalmazva – számos jótékony hatás érhető el, de fontos
hangsúlyozni óvatos használatukat és felismerni lehetséges mellékhatásaikat. Orv
Hetil. 2022; 163(9): 343–349.
Summary. The Hungarian and the European Society of Hypertension
guidelines mention Ephedrae herba, the drug of
Ephedra species (in Chinese “Mahuang”) as one of the causes
of secondary hypertension. The aim of our summary is to characterize the
Ephedra species used in medicine (based on the VIII.
Hungarian and the Chinese Pharmacopoeia), describe their history and their
components alongside with possible pharmacological effects, benefits,
side-effects, and interactions with other drugs. We demonstrate the herb’s
history from being a popular weight-loss product to being prohibited as a
dietary supplement and citing it in the World Anti-Doping Agency’s list. At the
same time, we explain the role of the Ephedra species in the
everyday medical practice. It is important to know their benefits in detail as
used in combination with other herbs in phytotherapy, and recognize their
possible side effects. Orv Hetil. 2022; 163(9): 343–349.
Terápiás hypothermia okozta QT-megnyúlás és „torsade de pointes” kamrai tachycardia
Authors: Tomcsányi János , Arányi Péter , Arabadzisz Hrisula 
Published: November 2022

Összefoglaló. A szerzők egy 44 éves, autoimmun betegségben szenvedő
nőbeteg kórlefolyását ismertetik. A váratlan kórházi kamrafibrillációt követő
sikeres resuscitatio után a beteg comatosus állapotban maradt, ezért terápiás
hypothermiában részesült. A hypothermiás kezelés hatására jelentős QT-megnyúlás
és „torsade de pointes” kamrai tachycardia lépett fel. A hypothermia okozta
szívritmuszavar oka a hőmérséklet-csökkenés kiváltotta QT-megnyúlás és korai
utódepolarizációs mechanizmusú triggerelt aktivitás. A szerzők felhívják a
figyelmet arra, hogy jelen tudásunk szerint enyhe hypothermiát javasolt
alkalmazni az ajánlásban szereplő hypothermiás tartományon belül. Orv Hetil.
2022; 163(13): 523–526.
Summary. The authors describe the course of disease in a 44-year-old
female patient with autoimmune disease. After successful resuscitation following
unexpected hospital ventricular fibrillation, the patient remained in a comatose
state and therefore received therapeutic hypothermia. Hypothermic treatment
resulted in significant QT prolongation and „torsade de pointes” ventricular
tachycardia. The probable cause of arrhythmia is the QT prolongation caused by
the hypothermia and the consequential early afterdepolarization and triggered
activity. The authors draw attention to the fact that – to the best of our
knowledge – milder hypothermia is recommended within the preset hypothermic
range. Orv Hetil. 2022; 163(13): 523–526.
Az aszimmetrikus és a szimmetrikus dimetilált arginin (ADMA/SDMA) klinikai és diagnosztikai jelentősége
Authors: Kovács Krisztián , Karvaly Gellért Balázs , Farkas Róbert , Vásárhelyi Barna 
Published: November 2022

Összefoglaló. Régóta folynak kutatások olyan újabb biomarkerek
azonosítására, amelyek segítik a krónikusan progrediáló, úgynevezett
civilizációs betegségek – például cardiovascularis kórképek,
vesefunkció-beszűkülés – korai felismerését. Az aszimmetrikus és a szimmetrikus
dimetil-arginin (ADMA és SDMA) kettő azon paraméterek közül, amelyek biológiai
hatásai évtizedek óta ismertek ugyan, ám biomarkerként egyelőre nem terjedtek el
a humán orvosi-diagnosztikai gyakorlatban. A fehérjearginin-metiltranszferázok
katalizálta folyamatban L-argininből keletkező vegyületek a
nitrogén-monoxid-szintáz aktivitásának gátlói. Mivel a nitrogén-monoxid számos
biológiai folyamat kulcsszereplője – gátolja az érpálya simaizomsejtjeinek
relaxációját, csökkenti a thrombocytaaggregációt, és gyulladáscsökkentő hatást
fejt ki –, termelődésének zavarai megnövelik a magas vérnyomás és
cardiovascularis betegségek kialakulásának kockázatát. Áttekintő közleményünkben
az ADMA és az SDMA mint lehetséges új diagnosztikai markerek, valamint a
társadalmi és orvosszakmai szempontból is kihívást jelentő betegségek
kapcsolatának bemutatását tűztük ki célul. Orv Hetil. 2022; 163(13):
500–505.
Summary. Research has long been underway to identify additional
biomarkers that will help in the early detection of chronic diseases of
civilization, such as cardiovascular disease and renal impairment. Asymmetric
and symmetric dimethyl arginine (ADMA and SDMA), two of the parameters whose
biological effects have been known for decades, have not yet been widely used as
biomarkers in human medical-diagnostic practice. In a process catalyzed by
protein arginine methyltransferases, compounds derived from L-arginine are
inhibitors of nitric oxide synthase activity. Because nitric oxide is a key
player in many biological processes – for instance, inhibiting the relaxation of
vascular smooth muscle cells, reducing platelet aggregation, and having
anti-inflammatory effect –, disturbances in its production increase the risk of
developing high blood pressure and cardiovascular disease. Therefore, in our
review paper, we aimed to present the relationship between ADMA and SDMA as
possible new diagnostic markers and socially and physically challenging
diseases. Orv Hetil. 2022; 163(13): 500–505.