bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relation of Young Children's Parasympathetic Reactivity During a Learning Task to Their Self‐Regulation and Early Academic Skills
Authors: Clark Caron A. C. , Caddell Kymberly 
Published: November 2022

AbstractThere is growing interest among educational researchers in using heart rate variability (HRV) as an index of children's capacity to regulate their physiological arousal. Links between HRV and young children's self‐regulation have, however, been inconsistent, and there is limited research on children's HRV in learning‐related contexts. HRV was collected from 86 children aged 3.41 to 5.83 years before, during, and after they engaged in a learning interaction with an examiner. Higher HRV during a pre‐learning episode and a larger drop in HRV during the learning interaction were associated with stronger behavioral performance on self‐regulation and early academic skill assessments. Children's capacity to modulate their HRV in response to learning opportunities may be linked to their broader self‐regulation and early academic skill development. Effects varied by episode and gender, underscoring a need for further research to rigorously evaluate the utility and generalizability of HRV in authentic educational settings.
Epistemic deontology and the Revelatory View of responsibility
Authors: Perrine Timothy 
Published: November 2022

AbstractAccording toUniversal Epistemic Deontology, all of our doxastic attitudes are open to deontological evaluations of obligation and permissibility. This view thus implies that we are responsible for all of our doxastic attitudes. But many philosophers have puzzled over whether we could be so responsible. This paper explores whether this puzzle can be resolved, and Universal Epistemic Deontology defended, by appealing to a view of responsibility it calls theRevelatory View. On that view, an agent is responsible for something when it reveals the kind of person the agent is. The paper explores four ways of developing the Revelatory View and argues that none of the views ultimately defends Universal Epistemic Deontology.
Occurrence and genotyping of Theileria equi in dogs and associated ticks in Egypt
Authors: Hegab Asmaa A. , Fahmy Magdy M. , Omar Hussein M. , Ghattas Souzan G. , Mahmoud Nisreen E. , Abuowarda Mai 
Published: November 2022

AbstractTheileriosis is a tick‐borne protozoal disease caused by a piroplasm of the genus Theileria. Hard ticks are obligate hematophagous ectoparasites that serve as vectors of Theileria spp. Studies of the presence of theileriosis in Egyptian dogs and associated ticks are scarce. This study was conducted to detect and identify Theileria spp. in dogs and Rhipicephalus sanguineus ticks and to monitor the epidemiological data of this disease. The prevalence rates of Theileria equi infection were 12.02%, 0.73%, 2.93%, and 1.83% by microscopic examination of dog blood, tick hemolymph, tick midgut, and tick salivary smears, respectively. Conversely, the T. equi prevalence in dog blood and associated ticks assessed by PCR was 25.81% and 10.42%, respectively. Epidemiological data about Theileria infection revealed a significant difference in the infection between different seasons and different dog breeds (p value <0.05), whereas host, sex, and age of dogs had no significant effect on the infection. Sequencing of PCR products showed that all PCR positive samples were infected with T. equi. Transmission electron microscopy (TEM) described the different stages of Theileria in the midgut and salivary gland of infected ticks. The current study confirmed that T. equi is not specific to equine hosts, and confirmed that dogs are a susceptible host to T. equi.
PUB30‐mediated downregulation of the HB24‐SWEET11 module is involved in root growth inhibition under salt stress by attenuating sucrose supply in Arabidopsis
Authors: Wang Yutao , Zhao Huan , Xu Liyuan , Zhang Hantao , Xing Hongjie , Fu Ying , Zhu Lei 
Published: November 2022

Summary
One of the strategies that plants adopt to cope with an unfavorable environment is to sacrifice their growth for tolerance. Although moderate salt stress can induce root growth inhibition, the molecular mechanisms regulating this process have yet to be elucidated.
Here, we found that overexpression of a zinc finger‐homeodomain family transcription factor, HOMEOBOX PROTEIN 24 (HB24), led to longer primary roots than in the wild‐type in the presence of 125 mM NaCl, whereas this phenotype was reversed for the hb24 loss‐of‐function mutant, indicating a negative impact of HB24 on salt‐induced root growth inhibition. We then found that salt stress triggered the degradation of HB24 via the ubiquitin–proteasome pathway, as mediated by a plant U‐box type E3 ubiquitin ligase 30 (PUB30) that directly targets HB24.
We verified that HB24 is able to directly bind to the promoters of Sugars Will Eventually be Exported Transporter 11/12 (SWEET11/12) to regulate their expression in roots. Through genetic and biochemical assays, we further demonstrated that the HB24‐SWEET11 module plays a negative role in salt‐induced root growth inhibition.
Therefore, we propose that under salt stress, PUB30 mediates HB24′s degradation, thereby downregulating the expression of SWEET11, resulting in reduced sucrose supply and root growth inhibition.
Correlation analysis of plasma lipid profiles and the prognosis of head and neck squamous cell carcinoma
Authors: Wang Siyu , Wang Li , Li Huan , Zhang Jiayu , Peng Jianmin , Cheng Bin , Song Ming , Hu Qinchao 
Published: November 2022

AbstractPurposeThis study aims to clarify whether blood lipid profiles are indicators of prognosis in patients with head and neck squamous cell carcinoma (HNSCC).MethodsThis retrospective study included 512 T1/2N0M0 HNSCC patients. The correlation between blood lipid profiles and progression‐free survival (PFS) and disease‐specific survival (DSS) was analyzed by multivariate analysis. The data from TCGA was also analyzed to investigate the expression levels and prognostic values of different lipoprotein receptors essential for specific lipid uptake.ResultsA high level of low‐density lipoprotein cholesterol (LDL‐C) indicated better PFS and DSS, and a low level of apolipoprotein A‐I (Apo A‐I) indicated better PFS, while a high level of apolipoprotein B (Apo B) indicated poorer PFS and DSS. The Apo A‐I receptor gene SCARB1 was upregulated and associated with poor survival in HNSCC patients. Activation of SCARB1 was implicated in a series of tumor‐promoting pathways. There was no significant correlation between the expression of LDL‐C and Apo B‐related receptors and prognosis.ConclusionA high level of LDL‐C and a low level of Apo A‐I are protective factors for HNSCC, while a high level of Apo B is a risk factor. The upregulation of SCARB1 may participate in the progression of HNSCC.
Does the Level of Syndesmotic Screw Insertion Affect Clinical Outcome after Ankle Fractures with Syndesmotic Instability?
Authors: Li Jin‐Kun , Yu Yi , Wu Ying‐Hua , Wang Jia , Zeng Xian‐Tie , Zhao Jia‐Guo 
Published: November 2022

ObjectiveAnkle fractures are often combined with syndesmotic instability, requiring reduction and stabilization. However, the optimal level for syndesmotic screw positioning remains unclear. This study aims to evaluate the effect of different syndesmotic screw insertion levels on postoperative clinical outcomes and determine whether an optimal level exists.MethodsThis retrospective study included data from 43 adult patients with acute closed ankle fractures combined with intraoperative evidence of unstable syndesmotic injuries who underwent open reduction internal fixation from January 1, 2017 to March 1, 2018 according to the inclusion and exclusion criteria. All 43 patients were divided into three groups based on the syndesmotic screw placement level: trans‐syndesmotic group: screw level of 2–3 cm; inferior‐syndesmotic group: screw level <2 cm; and supra‐syndesmotic group: screw level >3 cm. Clinical outcomes were measured at the final follow‐up, including the American Orthopedic Foot and Ankle Society (AOFAS) ankle‐hindfoot score, Olerud–Molander Ankle Score (OMAS), short‐form 36‐item questionnaire (SF‐36), visual analogue scale (VAS) score and restrictions in ankle range of motion (ROM). The relationships between screw placement level and clinical outcomes were analyzed with the Kruskal–Wallis H‐test and Spearman correlation analysis.ResultsThe median follow‐up duration was 15 months (range, 10–22 months). No patients developed fracture nonunion or malunion or experienced hardware failure. The outcome scoring systems showed an overall score for the entire group of 94.91 points for the AOFAS ankle‐hindfoot score, 83.14 for the OMAS, 96.65 for the SF‐36, 1.77 for the VAS, 9.14° for the restrictions in dorsiflexion, and 1.30° for the restrictions in plantarflexion. There were no significant differences among three groups in clinical outcomes (P > 0.05). Neither the AOFAS score nor OMAS had significant correlations with screw insertion level (P = 0.825 and P = 0.585, respectively). No postoperative arthritis or widening of the tibiofibular space was observed at the final follow‐up.ConclusionDifferent syndesmotic screw placement levels appear not to affect the clinical outcomes of ankle fractures with syndesmotic instability. No optimal level was observed in this study. Our findings suggest other clinically acceptable options apart from syndesmotic screw placement 2–3 cm above the ankle.
Induction of polyploids in acid lime (Citrus aurantifolia) through colchicine treatment of in vitro derived shoot tip explants
Authors: Bora Lokesh , Vijayakumar Rangasamy Muthusamy , Ganga Mathian , Meenakshi Ganesan Narayanapillai , Sarkar Mangaldeep , Kundu Manoj 
Published: November 2022

AbstractPolyploid breeding is an effective tool to induce variability in the existing population, specifically in the crops having very narrow genetic base such as acid lime. Hence, an experiment was conducted to induce polyploidy in acid lime through colchicine treatment. Higher frequency of triploids were obtained in 250 μM colchicine treatment (27.27%), whereas combination of 3× (21.42%), 4× (13.33%) and aneuploid (6.67%) were induced at 500 μM colchicine treatment. Measurement of stomatal density and guard cell size of colchiploids revealed that the former one has negative relation with ploidy level and a positive relation was observed between guard cell size and ploidy level. Further, area and size of nuclei also had a positive relation with ploidy level. Hence, stomatal density, guard cell and nuclei size can be used effectively as morphological marker for preliminary polyploid screening. From the experiment, it can be concluded that 500 μM colchicine treatment of in vitro derived shoot tip explants of acid lime is optimum for creating maximum possible variability through polyploidization in the existing acid lime population.
Curettage and sclerotherapy technique: A hybrid approach to superficial lymphatic malformation
Authors: Wang Huaijie , Zhou Jinbang , Lin Weilong , Xie Chong , Yang Weijia , Guo Zhengtuan 
Published: November 2022

AbstractObjectiveTo describe the curettage and sclerotherapy technique, a hybrid approach to treatment for superficial lymphatic malformations.MethodsA retrospective analysis of a lymphatic malformation data base was performed. Patients with superficial lymphatic malformation treated by curettage and sclerotherapy technique with bleomycin were included in this study. Safety and efficacy of the curettage and sclerotherapy technique with bleomycin were evaluated.ResultsBetween September 2019 and October 2021, 10 consecutive patients (male/female ratio: 4:6; mean age, 10.9 years; range, 3–35 years) presented with superficial lymphatic malformations that were subsequently treated by curettage and sclerotherapy technique with bleomycin. All lesions were located on the trunk and extremities. Each patient received one treatment session and a mean follow‐up of 12 months. We observed minor complications. No postoperative infections occurred in this series. No patient developed skin ulceration or necrosis. Scarring and recurrence occurred in one patient. Complete regression was confirmed for all 10 patients by photographic evaluation.ConclusionA curettage and sclerotherapy technique is proposed to treat superficial lymphatic malformation in this study. This technique seems to be safe and highly effective.
The Power to Govern
Authors: Shumener Erica 
Published: November 2022

AbstractI provide a new account of what it is for the laws of nature to govern the evolution of events. I locate the source of governance in the content of law propositions. As such, I do not appeal to notions of ground, essence, or production to characterize governance. After introducing the account, I use it to outline previously unrecognized varieties of governance. I also specify that laws must govern to have two theoretical virtues: explanatory power as well as a theoretical virtue I callexpansiveness. A theory is expansive, roughly, when it can do more with less.
“Trialectics” of Legal Interpretation
Authors: ČERVINKA LUKÁŠ LEV 
Published: November 2022

AbstractLaw is perceived as a stabilising mechanism in an everchanging world and, as such, is founded on the quest for the one “true” meaning of legal norms as a basis for the rule of law. But I shall suggest that it is futile to seek a fixed meaning of legal norms or the one “true” method for interpreting them. The argument will be built by first considering the “trialectics” between hermeneutics, linguistics, and jurisprudence, and then taking a systematic approach to law itself, to this end drawing inspiration from the work of Ferdinand de Saussure. I shall finally argue for the necessity of a more procedural understanding of the rule of law.
Luteal function in cyclic goats treated with human chorionic gonadotropin administered by intramuscular or intravaginal routes at the time of artificial insemination
Authors: Rodrigues Juliana Nascimento Duarte , Guimarães José Domingos , Rangel Paulo Sérgio Cerqueira , Oliveira Maria Emilia Franco , Brandão Felipe Zandonadi , Bartlewski Pawel Mieczyslaw , Fonseca Jeferson Ferreira 
Published: November 2022

AbstractHuman chorionic gonadotropin (hCG) has been used to improve goats reproductive efficiency. This study aimed to (i) evaluate if hCG administered by the intramuscular (i.m.) or intravaginal (i.vag.) route can be detected by a rapid β‐hCG test in blood plasma samples and (ii) document ovarian effects of hCG administered by both routes at the time of artificial insemination (AI) performed 60 h after oestrus synchronization in goats. Twenty‐two Alpine goats received two i.m. injections of 30 μg of d‐cloprostenol (Prolise®, Tecnopec, São Paulo, Brazil) 7.5 days apart. One day after the onset of oestrus (at the time of AI), the goats were randomly allocated to one of the three groups that received: control (n = 7): 0.3 ml of saline solution intravaginally; hCGi.m. (n = 7): 300 IU of hCG (Vetecor®; Hertape‐Calier, São Paulo, Brazil) i.m. and hCGi.vag. (n = 8): 300 IU of hCG deposited intravaginally. Blood samples were drawn at −1, 3, 6, 9 and 24 h after as well as on days 3, 7, 10, 13, 17 and 21 after hCG treatment/AI. All animals tested negative for hCG (ECO Diagnóstica, Corinto, Brazil) at −1 h, and all control animals tested negative throughout the entire blood collection period. All hCGi.m. animals tested positive from 3 h until D3 post‐AI but only 50% of hCGi.vag. goats tested positive during the present study. In all animals studied, mean circulating P4 concentrations increased (p < .05) from D3 to D7 after AI and then declined (p < .05) from D10 to D17 in control and hCGi.m. groups and from D17 to D21 in the hCGi.vag. group. Total cross‐sectional luteal area (CLA), mean colour Doppler area (DA), DA/CLA, mean high‐velocity Doppler area and HVDA/CLA all declined (p < .05) by D17–D21 in all animals studied. In summary: (i) human chorionic gonadotropin could consistently be detected in blood samples using the rapid β‐hCG test only in the hCGi.m. group; and (ii) there were no significant differences in the mean pregnancy rate, circulating P4 concentrations and various luteal parameters studied among Control, hCGi.m. and hCGi.vag. dose.
Regional soil contamination by halogenated organic pollutants attributed to E‐waste recycling, scattered industrialization and urbanization
Authors: Sun Jianqiang , Zhu Haofeng , Li Wangying , Li Shiyuan , Fang Li , Xia Qing , Tao Ninger , Wu Cheng , Zhang Anping 
Published: November 2022

AbstractRapid urbanization and industrialization can lead to the accumulation of toxic halogenated organic pollutants (HOPs) in soil environments, which poses a risk to the wider eco‐environment. In this study, we explored the occurrence and health risks of halogenated organic pollutants by analysing surface soil samples (n = 209) collected from various E‐waste dismantling, industrialized and urban areas, rural areas and remote areas in Zhejiang Province, China. The mean average concentrations (d.w.) and range (min–max) of the HOPs were Dechlorane plus (DP) = 0.14 ng/g (below detection limit (<DL) to 3.60 ng/g); short‐chain chlorinated paraffins (SCCPs) = 111.00 ng/g (<DL to 1736.00 ng/g); polychlorinated biphenyls (PCBs) = 1.20 ng/g (<DL to 15.00 ng/g); and polybrominated diphenyl ethers (PBDEs) = 21.30 ng/g (<0.16–673.00 ng/g). In the different areas sampled, the soil pollution level of HOP was in the order of E‐waste dismantling areas > industrialized and urban areas > rural areas > remote areas. Nevertheless, we observed high detection ratios in rural and remote areas, indicating scattered industrialization led to ubiquitous HOP soil pollution in the region.
Echocardiographic and radiographic aortic remodeling in cats with confirmed systemic hypertension
Authors: Holland Merrilee , Hofmeister Erik H. , Kupiec Caitlin , Hudson Judith , Fiske Kaitlin 
Published: November 2022

AbstractSystemic hypertension (SH) in cats may occur secondary to renal disease, hyperthyroidism, or idiopathic causes. Asymmetric dilation of the sinuses of Valsalva has been recognized in people with systemic hypertension as target organ damage (TOD). Aortic knob formation (lateral bowing of the aortic arch to proximal descending aorta on the posteroanterior/anteroposterior radiographic projection) is recognized as TOD in people due to SH. None of these changes have been reported in feline patients. The first objective of this retrospective case‐controlled study was to compare echocardiographic changes in the aorta of 76 cats with systemic hypertension (SH) to those seen in 76 cats with normal blood pressure (NBP). Our second objective was to have blinded reviewers assess heart size and aortic shape and size from available thoracic radiographs of 49/76 cats with SH and 46/76 cats with NBP. A two‐way unpaired t‐test with significance set at alpha = 0.01 was used to evaluate aortic echocardiographic parameters. The mean of the aortic diameter and length of each aortic cusp was significantly larger in cats with SH than in cats with NBP. The aortic cusps were considered altered in size in 62 of 76 cats with SH, 12/62 ≥ with 0.5 mm, and 50/62 ≥ 1.0 mm. No significant difference in the vertebral heart score (VHS) was noted between groups. The aortic knob to lateral margin of the trachea in cats with SH had an area under the curve (AUC) of 0.74 (95% CI:0.61‐0.87) with best cutoff of 1.12 cm with sensitivity of 81% and specificity of 69%.
ITS1 and cpb genetic polymorphisms in Algerian and Tunisian Leishmania infantum isolates from humans and dogs
Authors: Benikhlef Razika , Chaouch Melek , Abid Meriem Ben , Aoun Karim , Harrat Zoubir , Bouratbine Aida , BenAbderrazak Souha 
Published: November 2022

AbstractLeishmania (L.) infantum strains, isolated from varying hosts and clinical manifestations (cutaneous, visceral and canine leishmaniasis), were investigated in order to understand the genetic polymorphisms within this species in Algeria and Tunisia. Two DNA‐based typing methods were tested in order to evaluate their effectiveness against Multilocus enzyme electrophoresis (MLEE), widely considered as the reference method for Leishmania parasite typing. On the other hand, MLEE is cumbersome, high‐cost, time consuming and frequently does not detect intra‐species genetic polymorphisms. In this work, we used two molecular target regions to discriminate L. infantum strains, Internal transcribed spacer 1 (ITS1) and the cysteine proteinase B (cpb). The ITS1 region offers good resolution for Leishmania discrimination but does not spotlight intra‐species polymorphisms. In contrast, cpbE and cpbF PCR‐Sequencing demonstrated a certain variability within CL and VL Algerian and Tunisian L. infantum isolates. Following phylogenetic analyses of 44 L. infantum isolates, two main groups were identified, a group with 39 bp deletion in the cpb sequence, composed of cutaneous, visceral and canine isolates from both countries with no significant clinical or geographic distribution; these samples were typed as MON‐1, MON‐24, and MON‐80 zymodemes. A second group which presents a clear clusterization of Tunisian cutaneous strains belonging to the L. infantum MON‐24. This group, with no deletion in the mature domain of the cpb gene sequence, should be further explored with a higher number of samples.
On the Controllability and Observability of Temperature States in Metal Powder Bed Fusion
Authors: Wood Nathaniel , Hoelzle David J. 
Published: November 2022

Abstract
Powder bed fusion (PBF) is an additive manufacturing (AM) process that builds parts in a layer-by-layer fashion out of a bed of metal powder via the selective melting action of a laser or electron beam heat source. Despite its transformational manufacturing capabilities, PBF is currently controlled in the open loop and there is significant demand to apply closed-loop process monitoring and control to the thermal management problem. This paper introduces a controls theoretic analysis of the controllability and observability of temperature states in PBF. The main contributions of the paper are proofs that certain configurations of PBF are classically controllable and observable, but that these configurations are not strongly structurally controllable and observable. These results are complemented by case studies, demonstrating the energy requirement of state estimation under various, industry relevant PBF configurations. These fundamental characterizations of controllability and observability provide a basis for realizing closed-loop PBF temperature estimation.
Study on the Microstructure Evolution and Mechanical Properties of Cu/Cu41Sn11/Cu Solder Joint During High-Temperature Aging
Authors: Yang Gangli , Li Xiaoyan , Han Xu , Zhang Hu , Wen Linjie , Li Shanshan 
Published: November 2022

Abstract
The paper focused on the changes in microstructure and mechanical properties of the full Cu41Sn11 solder joint (Cu/Cu41Sn11/Cu) during isothermal aging at 420 °C. It was motivated by potential applications of Cu–Sn intermetallic compounds (IMCs) solder joint in third-generation wide bandgap semiconductor devices. Experimental results revealed that the Cu41Sn11 phase was unstable under high-temperature conditions, the full Cu41Sn11 joint transformed into the full α(Cu) joint (Cu/α(Cu)/Cu) joint at 150 h during thermal aging. The formed α(Cu) phase was a Cu solid solution with inhomogeneous Sn atomic concentration, and its crystal structure and orientation were consistent with the original Cu plate. The conversion of the Cu41Sn11 to α(Cu) was accompanied by the formation of voids due to the volume shrinkage effect, predominantly near the middle of the solder joint interface. The α(Cu) solder joint presented a decrease in strength but an increase in strain rate sensitivity index compared to the Cu41Sn11 solder joint. Furthermore, the strain rate sensitivity index of α(Cu) and Cu41Sn11 is lower than that of ordinary Sn solders. After the shear test, the fractures that occurred in Cu41Sn11 grains were brittle, while the fractures in α(Cu) grains were ductile.