bluuebunny/crossref_metadata_2025_split huggingface dataset:
A dual-clock-driven model emulating the effects of either Ano1 or IP3R knock-out on lymphatic muscle cell pace-making
Authors: Hancock E.J. , Zawieja S.D. , Macaskill C. , Davis M.J. , Bertram C.D. 
Published: November 2022

ABSTRACTLymphoedema, a common dysfunction of the lymphatic system, results in fluid accumulating between cells. Fluid return through the lymphatic vascular system is primarily provided by contractions of muscle cells in the walls of lymphatic vessels, driven by electrochemical oscillations causing rhythmic action potentials and associated surges in intracellular calcium ion concentration. There is incomplete understanding of the mechanisms involved in these repeated events, restricting the development of pharmacological treatments for dysfunction. Previously, we proposed a model where autonomous oscillations in the membrane potential (M-clock) drove passive oscillations in the calcium concentration (C-clock). In this paper, to model more accurately what is known about the underlying physiology, we extend this model to the case where the M-clock and the C-clock oscillators are both active but coupled together, and thus both driving the action potentials. This extension results from modifications to the model for the IP3receptor, a key C-clock mechanism. The synchronized dual-driving clock behaviour enables the model to match IP3receptor knock-out data, resolving an issue with previous models. We also use phase-plane analysis to explain the mechanisms for the dual-clock coupling. The model has the potential to help determine mechanisms and find targets for pharmacological treatment of lymphoedema.
Does it pay to be green? Evidence from banks in emerging markets
Authors: Al-Ajmi Jasim , Saudagaran Shahrokh , Kukreja Gagan , Fadel Sayed 
Published: November 2022

Purpose
The purpose of this study is twofold. The first is to examine the impact of environmental disclosure on banks’ performance, while the second is to investigate the moderating role of a country’s economic activities and institutional quality on the relationship between environmental activities disclosure and banks’ operational, financial and market performance.

Design/methodology/approach
The sample includes 246 banks from emerging markets from 2008 to 2020, comprising 1,899 bank-year observations. The independent regressors are environmental disclosure, two moderators and two sets of control (bank and country) variables. The dependent variables are return on assets, return on equity and Tobin’s Q. This study adopts ordinary least squares, panel fixed effect and instrumental variables generalized method of moments to estimate the parameters of the models.

Findings
This study reveals a negative relationship between environmental disclosure and bank performance, lending credence to the agency and neoclassical theories. The moderator regressors show positive influence on banks performance. The results indicate that it is difficult to make a business case for environmental commitment.

Practical implications
There is a need for effective monitoring by shareholders to ensure that funds allocated for environmental activities are spent wisely.

Originality/value
This study provides new evidence on the ways in which economic and institutional quality influence the environmental practices of banks in emerging and frontier markets.
Who uses drug checking services? Assessing uptake and outcomes at English festivals in 2018
Authors: Measham Fiona , Simmons Henry 
Published: November 2022

Purpose
This study aims to assess service user characteristics, uptake and outcomes for drug checking services offered to over 250,000 English festival-goers in summer 2018 and to compare findings with earlier years, wider festival-goers and the general population.

Design/methodology/approach
A total of 2,672 substances of concern were submitted by the public and tested by chemists in mobile laboratories on 24 show days at seven festivals. Results were embedded in 2,043 individually tailored brief interventions (BI) delivered by health professionals to 4,240 service users. Comparative data were collected through anonymous self-report surveys with 1,291 respondents at five of the same festivals.

Findings
Three percent of drug-using festival-goers received BI, 95% of whom had not previously accessed health services regarding their alcohol or other drug use. Drug checking service users were significantly more likely to be younger, male and past month polydrug users with a wider range of drugs consumed in the last month compared with the general festival population. For samples matching purchase intent, nearly half intended to reduce dosage, with younger and female service users significantly more likely to reduce dosage. For substances identified as other than expected, nearly two thirds disposed of them.

Social implications
Festivals are potential sites to deliver innovative health interventions and to monitor their outcomes, reduce the risk of poisoning and overdose, and facilitate access to follow-up support services.

Originality/value
This study suggests that there is value in event-based services that provide risk reduction communications directly to young adults engaged in higher risk drug use compared with wider event and general populations.
Do desire, anxiety and personal innovativeness impact the adoption of IoT devices?
Authors: Bhadauria Vikram S. , Chennamaneni Anitha 
Published: November 2022

Purpose
This study aims to investigate the threat phenomenon as perceived by Internet of Things (IoT) users and examines the role of anxiety, desire and personal innovativeness in the behavioral intention toward the usage of IoT devices.

Design/methodology/approach
A unified research model is developed based on the protection motivation theory, theory of reasoned action, theory of self-regulation and the review of relevant theoretical, empirical and practitioner literature. Data were collected from 315 assistive IoT device users and analyzed using partial least squares structural modeling.

Findings
The results indicate strong support for the proposed research model. All relationships, except one, were significant at the 0.05 level. Desire was found to play a direct as well as a moderating role between fear and behavioral intention to continue using assistive IoT devices, which was also directly influenced by anxiety and personal innovativeness.

Research limitations/implications
Understanding the security behaviors of IoT users will help researchers and practitioners develop preventive measures and robust security solutions for the IoT devices to avert any threats from cyber-attacks and to boost users’ confidence levels. Future research will benefit from replicating the study using longitudinal data.

Originality/value
This study is one of the first studies that integrate multiple perspectives to present a holistic research model. To the authors’ knowledge, anxiety, desire and personal innovativeness, key factors influencing fear and behavioral intention, have not been studied in the domain of adoption of IoT assistive devices. Additionally, the study offers a new dimension to IoT users’ security behaviors.
Measurement of city road network resilience in hazardous flood events
Authors: M.S. Mukesh , Katpatal Yashwant B. , Londhe Digambar S. 
Published: November 2022

Purpose
Recently, the serviceability of the transportation infrastructure in urban areas has become crucial. Any impact of the hazardous conditions on the urban road network causes significant disruption to the functioning of the urban region, making the city’s resilience a point of concern. Thereby, the purpose of the study is to examine the city’s recovery capacity to absorb the impacts of adverse events like urban floods.

Design/methodology/approach
This study examines the road network resilience for an urban flood event for zones proposed by the Municipal Corporation to develop multiple central business districts. This study proposes a novel approach to measure the resilience of road networks in an urban region under floods caused due to heavy rainfall. A novel Road Network Resilience Index (RNRI) based on the serviceability of the road network during floods is proposed, estimated using Analytic Hierarchy Process - Multiple Criteria Evaluation (AHP-MCE) approaches by using the change in street centrality, impervious area and road network density. This study examines and analyses the resilience of road networks in two conditions: flood and nonflood conditions. Resilience was estimated for both the conditions at the city level and the decentralized zone level.

Findings
Based on RNRI values, this study identifies zones having a lower or higher resilience index. The central, southern and eastern zones have lower road network resilience and western and northern zones have high road network resilience.

Practical implications
The proposed methodology can be used to increase road network resilience within the city under flood conditions.

Originality/value
The previous literature on road network resilience concentrates on the physical properties of roads after flood events. This study demonstrates the use of nonstructural measures to improve the resilience of the road network by innovatively using the AHP-MCE approach and street centrality to measure the resilience of the road network.
Kinematic modeling of a spatial three degrees-of-freedom compliant micro-motion parallel mechanism considering input coupling effect and bilateral restrained torsion
Authors: Song Zhicheng , Li Xiang , Yang Xiaolong , Li Yao , Wang Linkang , Wu Hongtao 
Published: November 2022

Purpose
This paper aims to improve the kinematic modeling accuracy of a spatial three-degrees-of-freedom compliant micro-motion parallel mechanism by proposing a modified modeling method based on the structural matrix method (SMM).

Design/methodology/approach
This paper analyzes the problem that the torsional compliance equation of the circular notched hinge is no longer applicable because it is subject to bilateral restrained torsion. The torsional compliance equation is modified by introducing the relative length coefficient. The input coupling effect, which is often neglected, is considered in kinematic modeling. The symbolic expression of the input coupling matrix is obtained. Theory, simulation and experimentation are presented to show the validity of the proposed kinematic model.

Findings
The results show that the proposed kinematics model can improve the modeling accuracy by comparing the theoretical, finite element method (FEM) and experimental method.

Originality/value
This work provides a feasible scheme for CMPM kinematics modeling. It can be better applied to the optimization design based on the kinematic model in the future.
The first half century of industrial robot: 50 years of robotic developments
Authors: Bogue Robert 
Published: November 2022

Purpose
This paper aims to trace the technological and commercial developments in robotics over the last 50 years, from 1973, the year in which this journal was founded, to the present day.

Design/methodology/approach
Following an introduction, this identifies key robot developments on a decade-by-decade basis and considers research, products, applications and corporate activity and also highlights many of the enabling technologies. Brief conclusions are draw.

Findings
The robot industry has changed beyond all recognition during the last half century. Enabled by developments in microelectronics, computing, sensors, imaging technologies, data communication and power sources, today robots satisfy a multitude of applications and play a role in almost every sphere of human activity.

Originality/value
This provides a detailed review of robotic developments during the last 50 years.
Chief financial officer’s educational background from reputable universities and financial reporting quality
Authors: Harymawan Iman , Minanurohman Adib , Nasih Mohammad , Shafie Rohami , Ismail Ismaanzira 
Published: November 2022

Purpose
This study aims to examine the relationship between the educational background of Chief Financial Officers (CFOs) from reputable universities and financial reporting quality (FRQ). Educational background is divided into two categories: an undergraduate degree from a reputable university and a Master of Business Administration (MBA) degree from a reputable university.

Design/methodology/approach
This study uses data from all companies listed on the Indonesia Stock Exchange from 2010 to 2019, except for financial companies, and obtains 2,583 research samples. The least-squares regression analysis model was used in this study.

Findings
This study finds that the educational background of CFOs with a bachelor’s degree and CFOs with an MBA from reputable universities has a positive and significant relationship with FRQ. This study also performs an additional analysis with high-low growth and high-low tech and robustness testing with coarsened exact matching method and Heckman to corroborate the results.

Research limitations/implications
This study provides a theoretical contribution to the literature on the relationship between CFOs’ educational background and FRQ in Indonesia. It is also expected to contribute to the implementation of company policies, management and educational institutions in Indonesia.

Originality/value
This study provides a novel measurement of CFO reputation, measured using the ranking of CFO alumni from reputable universities and its association with FRQ.
Asymmetric volatility spillover between hospitality sub-sectors during COVID-19: evidence from the USA
Authors: Marobhe Mutaju Isaack , Kansheba Jonathan Mukiza Peter 
Published: November 2022

PurposeThis article examines dynamic volatility spillovers between stock index returns of four main hospitality sub-sectors in US during the coronavirus disease 2019 (COVID-19) pandemic. These are tourism and travel, hotel and lodging, recreational services and food and beverages. Volatility spillovers are explicitly used as accurate and informative proxies for risk contagion between sectors during turbulent times.Design/methodology/approachThe authors employ dynamic conditional correlation-generalized autoregression heteroskedasticity (DCC-GARCH) and wavelet coherence analysis (WCA) to analyze the phenomenon. The authors’ timeframe is divided into three main sub-periods, namely the pre-pandemic, the first wave and the second wave periods.FindingsThis study’s results reveal immense negative shocks in returns of all four sub-sectors on the Black Monday (8th March 2020). Moreover, high volatility persistence was observed during both waves with an exception of tourism and travel which exhibited lower volatility persistence during the second wave. The authors discovered magnified contagion effects between tourism and travel, hotel and lodgment and recreational services during the first wave of the pandemic with tourism and travel being the main volatility transmitter. Lower magnitudes of spillovers were observed between food and beverages and other sub-sectors with a decoupling effect being evident during the second wave.Research limitations/implicationsThis study’s findings contribute to the contagion theory by providing evidence of disproportional volatility spillover among hospitality sub-sectors despite being exposed to similar turbulent economic conditions.Practical implicationsCrucial implications can be drawn from this study’s findings to assist in risk management, asset valuation and portfolio management. The importance of close monitoring, safety measures, international diversification and adequacy of liquid assets during health crises cannot be stresses enough for hospitality firms. Retail investors, speculators and asset managers can take advantage of this study’s findings to design trading strategies and hedge against risk.Originality/valueA body of knowledge pertaining to effects of crises such as COVID-19 on hospitality stocks has been proliferating. Nonetheless, there is still a relative dearth of empirical literature on volatility spillover between hospitality sub-sectors especially during periods of rising economic uncertainties.
SDGs, COVID-19 and institutional pressures on organizations
Authors: Galleli Barbara , Santos Joyce Aparecida Ramos , Teles Noah Emanuel Brito , Freitas-Martins Mateus Santos , Onevetch Raquel Teodoro 
Published: November 2022

PurposeThis article answers the following research question: How do institutional pressures influence the re(actions) of organizations in relation to the Sustainable Development Goals (SDGs) in the context of the coronavirus disease 2019 (COVID-19) pandemic?Design/methodology/approachThe present research was conducted through the search and review of online secondary sources based on a critical and exploratory analysis. The data were obtained from the Global Compact Brazilian Committee (Rede Brasil do Pacto Global, in Portuguese) and analyzed by means of qualitative content analysis with the support of the ATLAS.ti software.FindingsThe results have showed the role of organizations in dealing with the impacts provoked by the current COVID-19 scenario. However, the association of actions implemented by organizations is evident in some SDGs, but not in all and not with the same intensity. There is a higher incidence of SDG 3 (Good health and well-being), which is linked to 278 actions. Regarding institutional pressures, we noticed a higher incidence of normative pressures, which may indicate a sense of responsibility towards employees and other stakeholders related to the prevention of the impacts caused by the pandemic.Practical implicationsThe findings presented here can encourage companies to better direct their efforts to fight the virus without neglecting the 2030 Agenda.Social implicationsThe authors intend to encourage institutions that may exert coercive, normative, and mimetic pressures to recognize the impacts of their influence and better direct it to the interests of society during and after the pandemic.Originality/valueThis research investigates organizational actions in the context of COVID-19 from an institutional theory perspective.
Shrinkage behaviour of material extrusion steel 316L: influence of primary 3D printing parameters
Authors: Obadimu Solomon O. , Kourousis Kyriakos I. 
Published: November 2022

Purpose
The wide application of metal material extrusion (MEX) has been hampered by the practicalities associated with the resulting shrinkage of the final parts when commercial three-dimensional (3D) printing equipment is used. The shrinkage behaviour of MEX metal parts is a very important aspect of the MEX metal production process, as the parts must be accurately oversized to compensate for shrinkage. This paper aims to investigate the influence of primary 3D printing parameters, namely, print speed, layer height and print angle, on the shrinkage behaviour of MEX Steel 316L parts.

Design/methodology/approach
Two groups of dog-bone and rectangular-shape specimens were produced with the BASF Ultrafuse Steel 316L metal filament. The length, width and thickness of the specimens were measured pre- and post-debinding and sintering to calculate the percentile shrinkage rates. Analysis of variance (ANOVA) was used to evaluate and rank the significance of each manufacturing parameter on shrinkage. Typical main print quality issues experienced in this analysis are also reported.

Findings
The shrinkage rates of the tested specimens ranged from 15.5 to 20.4% along the length and width axis and 18.5% to 23.1% along the thickness axis of the specimens. Layer height and raster angle were the most statistically significant parameters influencing shrinkage, while print speed had very little influence. Three types of defects were observed, including surface roughness, surface deformation (warping and distortion) and balling defects.

Originality/value
This paper bridges an existing gap in MEX Steel 316L literature, with a focus on the relationship between MEX manufacturing parameters and subsequent shrinkage behaviour. This study provides an in-depth analysis of the relationship between manufacturing parameters – layer height, raster angle and print speed and subsequent shrinkage behaviour, thereby providing further information on the relationship between the former and the latter.
Treatment with brodalumab is not associated with improved sleep problems in real‐life patients with plaque psoriasis: Results of the ProLOGUE study
Authors: Mizutani Yoko , Kanai Yasumasa , Murotani Kenta , Honma Masaru , Higashiyama Mari , Kobayashi Satomi , Nomura Takanobu , Seishima Mariko , Imafuku Shinichi 
Published: November 2022

AbstractPsoriasis impacts various aspects of patients' health‐related quality of life and is associated with sleep problems. However, research discussing the associations between interleukin‐17 blockage therapies and sleep problems in patients with psoriasis is insufficient. We aimed to assess the effectiveness of brodalumab in alleviating sleep problems in real‐life patients with plaque psoriasis. This analysis was part of the single‐arm, open‐label, multicenter, prospective, cohort study, ProLOGUE (study period October 2017–March 2020), which involved Japanese patients with plaque psoriasis. Assessments included correlation of Medical Outcomes Study Sleep Scale–Revised (MOS Sleep‐R) scores (Sleep Problems Index‐II [SPI‐II] and MOS Sleep‐R subscale scores) with multiple patient‐reported outcome scores and the Psoriasis Area and Severity Index (PASI) at baseline. Additionally, change from baseline in MOS Sleep‐R scores was assessed at weeks 12 and 48 of brodalumab treatment. Seventy‐three patients were enrolled (male 82.2%, median age 54.0 years). At baseline, the SPI‐II score correlated with the Patient Health Questionnaire‐8 score (Spearman correlation coefficient [ρ] = −0.474) and weakly correlated with the Itch Numeric Rating Scale (NRS; ρ = −0.366), Skin Pain NRS (ρ = −0.275), and all Treatment Satisfaction Questionnaire for Medication‐9 domain scores (ρ = 0.270, ρ = 0.303, and ρ = 0.322 for effectiveness, convenience, and global satisfaction, respectively) but did not correlate with the PASI score. The SPI‐II score and MOS Sleep‐R subscale scores, except the Snoring score (p = 0.0319), did not significantly change from baseline to week 12 of brodalumab treatment. In conclusion, treatment with brodalumab did not improve overall sleep problems in real‐life patients with plaque psoriasis, suggesting that sleep problems require attention in daily clinical practice (Japan Registry of Clinical Trials identifier, jRCTs031180037).
Is Social Trust a Governance Mechanism? Evidence From Dividend Payouts of Chinese Firms
Authors: Goodell John W. , Li Mingsheng , Liu Desheng , Wang Ying 
Published: November 2022

AbstractWhile management studies show that micro‐level trust within and between firms affects firm performance and innovation, it is unclear how macro‐level trust, namely social trust, affects corporate decisions. Addressing this is important because micro‐level trust is shaped by macro‐level social norms. A growing literature finds that corporations are influenced by local social norms. Drawing from this insight and using various measures of social trust, we examine the impact of social trust on dividend payouts. We find that levels of social trust, both in terms of directly measured trust and trust inferred from concomitant levels of civic social capital, negatively impact dividend payouts of local firms across Chinese provinces. We argue that community social trust supplies governance and plays a substitute role for dividend payouts, with a higher level of social trust engendering a lower demand for dividend payouts. This negative effect is more pronounced for younger firms, companies with high growth potential and firms in regions of less‐developed institutional environments. We further show that agency cost plays an important mediating role, since high social trust reduces agency cost, jointly affecting dividends. Firms in high‐trust regions make meaningful use of their greater retained earnings for research and development and innovations.