bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intercropping with Achyranthes bidentata alleviates Rehmannia glutinosa consecutive monoculture problem by reestablishing rhizosphere microenvironment
Authors: Liu Yazhou , Liu Ye , Zeng Chunli , Wang Juanying , Nyimbo Witness Joseph , Jiao Yanyang , Wu Linkun , Chen Ting , Fang Changxun , Lin Wenxiong 
Published: November 2022

BackgroundThe consecutive monoculture of Rehmannia glutinosa leads to a serious decrease in its production and quality. Previous studies have demonstrated that intercropping altered species diversity and rhizosphere microbial diversity. However, it remained unknown whether the impaired growth of monocultured plants could be restored by enhanced belowground interspecific interactions.MethodIn the present research, a continuous cropping facilitator Achyranthes bidentata was intercropped with R. glutinosa under pot conditions, and three different types of root barrier treatments were set, including that complete belowground interaction (N), partial belowground interaction (S), and no belowground interspecies interaction (M), with the aims to investigate belowground interaction and the underlying mechanism of alleviated replanting disease of R. glutinosa by intercropping with A. bidentata.ResultsThe results showed that the land equivalent ratio (LER) of the two years was 1.17, and the system productivity index (SPI) increased by 16.92 % under S treatment, whereas no significant difference was found in N and M regimes. In the rhizosphere soil, intercropping systems had significantly increased the contents of sugars and malic acid in the soil of R. glutinosa, together with the content of organic matter and the invertase and urease activities. Meanwhile, intercropping increased the community diversity of fungi and bacteria, and the relative abundance of potential beneficial bacteria, such as Bacillus, Nitrospira, and Sphingomonas, despite the pathogenic Fusarium oxysporum was still the dominant genus in the rhizospheric soil of R. glutinosa under various treatments. The results of antagonism experiments and exogenous addition of specific bacteria showed that Bacillus spp. isolated from rhizosphere soil had a significant antagonistic effect on the pathogen of R. glutinosa.ConlusionTaken together, our study indicated that the R. glutinosa//A. bidentata intercropping systems alleviate the consecutive monoculture problem of R. glutinosa by recruiting beneficial bacteria. The studies we have conducted have a positive effect on sustainable agricultural development.
Construction of a density mutant collection in bitter gourd via new germplasms innovation and gene functional study
Authors: Yu Renbo , Niu Yu , Wang Xiaoyi , Yang Kaili , Han Xu , Liu Zhaohua , Qi Zhiqiang , Yang Yan 
Published: November 2022

Although a few studies have elucidated the creation of bitter gourd mutants, the suitable concentration and duration of ethyl methanesulfonate (EMS) mutagenesis have not been determined. In this study, mutant collection was conducted to create new germplasms and widen genetic diversity. By employing the seeds of the inbred line Y52 as the mutagenic material, EMS as the mutagen, and the suitable mutagenic conditions for bitter gourd seeds (EMS concentration 0.2%, mutagenic time 10 h), we mutated 10,000 seeds and acquired 3223 independent M1 lines. For the randomly selected 1000 M2 lines, 199 M2 lines with visible phenotypes were found, and 167 M2 lines were mutants of fruit shape, size, and tubercles. Furthermore, fourteen dwarf, eleven leaf color, five leaf shape, and eight meristem defect mutants were discovered in this mutant collection. In addition, three lines of 1253, 2284, and 3269 represented recessive mutants crossed with Y52. Furthermore, the yellow leaf lines of 2284 and 3269 were not mutated at the same gene locus. This study constructed a mutant collection through innovative new germplasms and provided valuable resources for bitter gourd breeding and functional gene research.
Money lies and extramarital ties: Predicting separate and joint occurrences of financial deception and extramarital infidelity
Authors: Dew Jeffrey P. , Saxey Matthew T. , Mettmann Alison 
Published: November 2022

IntroductionAlthough spouses frequently financially deceive each other (MFD; i.e., marital financial deception), few studies have examined this relationship behavior. The purpose of our study is to examine predictors of separate and joint occurrences of MFD and extramarital affairs (EMI). We chose the predictors we tested using social exchange theory (SET).MethodsWe used a national sample of married individuals and multinomial logistic regression analyses to examine how different predictors were associated with membership in three different groups (MFD with no EMI, EMI with no MFD, and both MFD and EMI) relative to the group of participants who reported neither behaviors.ResultsRelationship satisfaction was associated with a lower likelihood of being in the MFD-only group, moral commitment was negatively associated with membership in both EMI groups, and personal dedication commitment was negatively associated with membership in both MFD groups. Flirting with someone other than one’s spouse was positively associated with being in all three groups relative to the reference group. The personal importance of religion was not associated with group membership.DiscussionMoral commitment, personal dedication commitment, and flirting with someone other than one’s spouse predicted these two types of marital deception. It is likely that other issues that affect marital outcomes, comparisons, and monitoring alternatives to the relationship may predict MFD and/or EMI.
Conversational hypnosis versus standard of care to reduce anxiety in patients undergoing marker placement under radiographic control prior to breast cancer surgery: A randomized, multicenter trial
Authors: Lemoine Lydie , Adam Virginie , Galus Xavier , Siles Pascale , Coulon Agnès , Grenier-Desforges Jeannette , Orabona Joseph , Kergastel Isabelle , Wagner Pierre , Salleron Julia , Tosti Priscillia , Huin-Schohn Cécile , Merlin Jean-Louis , Etienne Rémi , Henrot Philippe 
Published: November 2022

BackgroundSurgery is a cornerstone of breast cancer management. Prior to surgery, a wire marker is placed at the site of the tumor, to enable the surgeon to accurately localize the lesion during later surgery. This procedure can generate considerable anxiety for many patients. We investigated the value of conversational hypnosis (CH) in reducing anxiety in patients undergoing preoperative wire placement under radiographic control.MethodsRandomized, multicentre study in 7 centers in France. Inclusion criteria were patients aged &gt;18 years with an Eastern Cooperative Oncology Group performance status ≤2, scheduled to undergo preoperative wire placement in one or several breast lesions. Patients were randomized in a 1:1 ratio, stratified by center to undergo preoperative wire placement with or without the use of CH by a radiological technician trained in the CH technique. The primary endpoint was the percentage of patients with an anxiety score ≥ 6 on a visual analog scale ranging from 0 (absence of anxiety) to 10 (maximal anxiety). Secondary endpoints were pain score, perceived duration reported by the patient, technician satisfaction with their relationship with the patient, and ease of marker insertion reported by the radiologist. Semi-structured interviews were performed with patients to assess their perception of the marker placement procedure.ResultsThe trial was prematurely interrupted for futility after a planned interim analysis after accrual of 167 patients, i.e., half the planned sample size. Prior to marker placement, 29.3% (n = 24) of patients in the control group had an anxiety score ≥ 6, versus 42.3% (n = 33) in the CH group (p = 0.08). After marker placement, the change of anxiety score was not significantly different between groups (11.0% (n = 9) versus 14.3% (n = 11), p = 0.615). There was no significant difference in any of the secondary endpoints. In the interviews, patients from both groups frequently spoke of a feeling of trust.ConclusionThis study failed to show a benefit of conversational hypnosis on anxiety in patients undergoing marker placement prior to surgery for breast cancer. The fact that some caregivers had learned this personalized therapeutic communication technique may have had a positive impact on the whole caregiving team.Trial registrationThe study was registered with ClinicalTrials.gov (NCT02867644).
Testing some psychometric properties of the Italian version of the Skin Cancer Index: A questionnaire for measuring quality of life in patients with non-melanoma skin cancer
Authors: Samela Tonia , Raimondi Giulia , Sampogna Francesca , Ricci Francesco , Fania Luca , Mastroeni Simona , Fusari Roberta , Salcedo Nidia Melo , Dattolo Anna , Papanikolaou Elena Sofia , Abeni Damiano 
Published: November 2022

ObjectivesNon-melanoma skin cancers (NMSC) include two main types: basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC). Generic Health-Related Quality of Life (HRQoL) instruments revealed little to no HRQoL impairment in NMSC patients. Instead, the use of specific skin disease HRQoL tools contradicted those observations. For example, the Skin Cancer Index (SCI) was suggested as a validated instrument for the evaluation of the impact of skin cancers on HRQoL, and has already been validated in several languages, but not in Italian. The aim of this study is to testing some psychometric properties of the Italian version of the SCI questionnaire in a large sample of NMSC patients.MethodsThis is a cross-sectional, single-center, observational study. Firstly, different factor models proposed in the literature were compared and the model with the best fit was identified. Secondly, the psychometric properties of the SCI, convergent validity and reliability, were evaluated.ResultsThe sample was composed of 371 NMSC patients. The factor analysis revealed that a revised version of the original model had the best fit [χ2(df = 85) = 354.53, p &lt; 0.001, RMSEA = 0.09, CFI = 0.98, TLI = 0.97, SRMR = 0.03]. The SCI had satisfactory internal consistency for all subscales (Emotional subscale: ordinal alpha = 0.95; Social subscale: ordinal alpha = 0.94; Appearance subscale: ordinal alpha = 0.94). The convergent validity with Skindex-17 psychosocial subscale was adequate for all the SCI subscales (Emotional Subscale: rho = −0.50; Social Subscale: rho = −0.54; Appearance subscale: rho = −0.44; Total Skin Cancer Index: rho = −0.56; and p &lt; 0.001).ConclusionThe tested psychometric properties of the Italian version of the SCI may suggest that it is an appropriate tool to measure the HRQoL in NMSC patients, however, further studies are needed in order to confirm and tested other psychometric features of this tool.
The physiological mechanism and effect of resistance exercise on cognitive function in the elderly people
Authors: Cheng Aijie , Zhao Zhiwei , Liu Hengxu , Yang Jinxin , Luo Jiong 
Published: November 2022

BackgroundAs brain function declines and cognitive ability declines, the benefits of resistance exercise to the brain of older people are gradually gaining attention.ObjectiveThe purpose of this review is to explore the mechanism and relationship between physiological factors such as vascular and neuronal degeneration and cognitive decline, and to categorize the differences in the effects of an acute and chronic resistance exercise intervention on cognitive function in healthy elderly people and the possible regulators of cognitive effects.MethodsUsing PubMed, Elsevier, Web of Science, X-MOL, CNKI, and Taiwan academic literature database, the research papers published in relevant journals at home and abroad until April 2022 were searched with Chinese and English keywords such as Resistance exercise, the elderly, hippocampus, memory performance, neurons, cognitive function. Pedro scale was used to check the quality of various documents, and the relevant research documents were obtained with the resistance exercise elements as the main axis for comprehensive analysis.Results and conclusion(1) Resistance exercise can have a beneficial effect on the brain function of the elderly through blood flow changes, stimulate nerve conduction substances and endocrine metabolism, promote cerebrovascular regeneration and gray matter volume of the brain, and prevent or delay the cognitive function degradation such as memory and attention of the elderly; (2) Acute resistance can temporarily stimulate hormone secretion in vivo and significantly improve the effect of short-term memory test, but it has little effect on the cognitive performance of the elderly; (3) Moderate-high intensity resistance exercise (50–80%1RM, 1–3 times/week, 2–3 groups/time) lasting for at least 6 months is more prominent for the improvement of cognitive function of the elderly, while the parameters such as resistance exercise intensity, exercise amount, duration, evaluation test time and differences of subjects may have different degrees of influence on cognitive benefits.
Association between socioeconomic status and arteriosclerotic cardiovascular disease risk and cause-specific and all-cause mortality: Data from the 2005–2018 National Health and Nutrition Examination Survey
Authors: Shen Ruihuan , Zhao Ning , Wang Jia , Guo Peiyao , Shen Shuhui , Liu Detong , Liu Donghao , Zou Tong 
Published: November 2022

BackgroundMorbidity and mortality of arteriosclerotic cardiovascular disease (ASCVD) varied according to socioeconomic status (SES), and evidence on the association between SES and ASCVD risk, and cause-specific and all-cause mortality was nevertheless lacking in large-scale or population-based studies.MethodsA multicycle cross-sectional design and mortality linkage study was conducted using data from Continuous National Health and Nutrition Examination Survey (NHANES) in the United States, including public use linked mortality follow-up files through December 31, 2019. Poverty income ratio (PIR) served as a SES index. A series of weighted Logistic regressions and Cox proportional hazards regressions were used to investigate the association between the SES and the risk of ASCVD and mortality, respectively.ResultsThe study sample was comprised of 30,040 participants aged 20–85 years old during the 2005–2018 period. Weighted Logistic regression models consistently indicated significant relationship between people experiencing poverty and increased risk of ASCVD, and linear trend tests were all statistically significant (all P for trend &lt; 0.001). Additionally, weighted Cox regression analysis consistently demonstrated that the hazards of cause-specific and all-cause mortality increased, with the decrease of each additional income level, and trend analyses indicated similar results (all P for trend &lt; 0.001).ConclusionsOur study confirmed that the SES was strongly linked to living with ASCVD, and cause-specific and all-cause mortality, even after adjusting for other factors that could impact risk, such as the American Heart Association (AHA)'s Life's Simple 7 cardiovascular health score and variables of age, sex, marital status, education, and depression severity.
Associations of physical activity with cognitive function and daily physical function among Chinese individuals with heart disease: A cross-sectional study
Authors: Dong Xiaosheng , Yi Xiangren , Jia Ningxin , Ding Meng , Zhou Yanan , Tian Caijun 
Published: November 2022

BackgroundTo investigate the associations between different dimensions of physical activity (PA), cognitive function, and daily physical function in Chinese individuals with heart disease.Materials and methodsThis study included 2,792 individuals from the China Health and Retirement Longitudinal Study conducted in 2015. Physical activity (PA) was divided into vigorous PA (VPA), moderate PA (MPA), and light PA (LPA). Linear and logistic regression models were established to assess the associations among the indicators.ResultsCompared with taking no PA, MPA, and VPA at a frequency of 6–7 d/w had lower risks of impaired daily physical function (OR = 0.47, 95% CI: 0.25, 0.91; OR = 0.57, 95% CI: 0.37, 0.88) and higher cognitive function scores (β = 1.22, 95% CI: 0.42, 2.03; β = 1.08, 95% CI: 0.43, 1.73), while VPA at 3–5 d/w had lower cognitive function scores (β = −1.96, 95% CI: −3.51, −0.40). Light PA (LPA) with a duration of 30–119 min/d had a lower risk of impaired daily physical function (OR = 0.59, 95% CI: 0.36, 0.97). Moderate PA (MPA) and VPA of 30–119 min/d had higher cognitive function scores (β = 1.43, 95% CI: 0.49, 2.37; β = 1.30, 95% CI: −0.56, 2.06). The 1,800–2,999 METs had the lowest risks of impaired daily physical function and the highest cognitive function scores (OR = 0.18, 95% CI: 0.04, 0.75; β = 2.94, 95% CI: 1.67, 4.21).ConclusionModerate PA (MPA) and LPA with a frequency of 6–7 d/w and a duration of 30–119 min/d, and PA in 1,800–2,999 MET min/week were most closely related to better cognitive and daily physical function, while VPA (3–5 d/w; ≥300 min/w) may be related to low cognition, but high-quality research is necessary to prove causality.Trial registrationIRB00001052-11015.
HIV sero-status disclosure and associated factors among HIV positive women in East Africa: Systematic review and meta-analysis. Implications for prevention of mother-to-child HIV transmission
Authors: Mosisa Getu , Mulisa Diriba , Oluma Adugna , Bayisa Lami , Merdassa Emiru , Bayisa Diriba , Tamiru Afework , Tolossa Tadesse , Chala Diriba Dereje , Fetensa Getahun , Wakuma Bizuneh 
Published: November 2022

BackgroundWomen's HIV-positive disclosure plays a pivotal role to achieve the goal of preventing mother-to-child transmission (PMTCT) among pregnant women in particular. Although several primary studies were conducted in the different countries of East Africa, no study concluded the prevalence of women's HIV status disclosure and associated factors in East Africa. Therefore, the current study aimed to assess the pooled prevalence of disclosure status and associated factors among women in East Africa.ObjectivesTo assess the pooled prevalence of HIV sero-status disclosure and associated factors among women in East Africa.MethodsHINARI, PubMed, and Cochrane Library databases were searched. The data were extracted using a Microsoft Excel spreadsheet and STATA v 14.1 was used for the analysis. The Funnel plots and Egger's statistical test was used to check publication bias. Heterogeneity was assessed by conducting sensitivity and subgroup analyses.ResultThe pooled prevalence of sero-status disclosure among women in East Africa was 73.77% (95%CI 67.76, 79.77). Knowing partner's sero-status (OR = 10.04(95%CI 3.36, 31.84), married (OR = 2.46 (95%CI 1.23, 4.89), smooth relationship (OR = 3.30 (95%CI 1.39, 7.84), and discussion on HIV before the test (OR = 6.96 (95%CI 3.21, 15.05) were identified determinants of HIV sero-status disclosure.ConclusionThe current systematic and meta-analysis revealed that nearly one-fourth of women had not disclosed HIV sero-status to at least one individual. Knowing the partner's HIV sero-status, being married, having a smooth relationship, and discussing on HIV before the test were determinants of disclosure status. Therefore, disclosure of HIV-positive sero-status among women living with HIV needs to be strengthened.
Limited social support is associated with depression, anxiety, and insomnia in a Japanese working population
Authors: Omichi Chie , Kaminishi Yuki , Kadotani Hiroshi , Sumi Yukiyoshi , Ubara Ayaka , Nishikawa Kohei , Matsuda Arichika , Ozeki Yuji 
Published: November 2022

BackgroundLack of social support is associated with depression, anxiety, and insomnia. This study aimed to determine the source of support related to depression, anxiety, and insomnia among Japanese workers.MethodsAs part of a cohort study, we conducted a questionnaire survey among city government employees in Koka City, Shiga Prefecture, Japan, from September 2021 to March 2022. We used the Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder−7 (GAD-7), and Insomnia Severity Index (ISI) to assess depressive symptoms, anxiety symptoms, and insomnia, respectively. We used the Brief Job Stress Questionnaire (BJSQ) to assess job stressors and social support (from supervisors, colleagues, and family).ResultsA total of 1,852 Japanese employees (38.4% male, 45.9 ± 12.9 years) participated in the survey, with 15.5, 10.8, and 8.2% of the participants having depressive symptoms (PHQ-9 ≥ 10), anxiety symptoms (GAD-7 ≥ 10), and insomnia (ISI ≥ 15), respectively. The logistic regression analysis suggested that job stressors were associated with depressive symptoms (p &lt; 0.001), anxiety symptoms (p &lt; 0.001), and insomnia (p = 0.009). In contrast, support from co-workers (p = 0.016) and family members (p = 0.001) was associated with decreased depressive symptoms. Support from family members was associated with decreased insomnia (p = 0.005).ConclusionSocial support from co-workers and family may be associated with reduced depressive symptoms, and family support may be associated with reduced insomnia in the Japanese working population.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/NCT03276585.
Immunological role and prognostic value of SPARCL1 in pan-cancer analysis
Authors: He Kangwei , Li Changjiu , Yuan Hui , Jiang Kang , Deng Gang 
Published: November 2022

Background: Secreted protein acidic and rich in cysteine-like 1 (SPARCL1) was a kind of extracellular matrix glycoprotein. SPARCL1 was strongly inhibited in most cancers. However, the potential functions of SPARCL1 in the pan-cancer cohort have not been widely studied.Methods: We evaluated the transcriptional level and the prognostic value of SPARCL1 in 33 types of cancer and revealed the relationship between genetic alterations of SPARCL1 and the tumor mutation burden. Meanwhile, we assessed the correlations between SPARCL1 and tumor-infiltrating lymphocytes across cancers.Results: The transcriptional level of SPARCL1 was inhibited in most cancers. Although SPARCL1 was down-regulated in most cancers, SPARCL1 might play a protective or detrimental role in different cancers. We demonstrated that mutation count was elevated in the altered SPARCL1 group in several cancers. Additionally, we found a significant positive correlation between SPARCL1 and macrophage infiltration levels in most cancers. Especially, marker sets of M2 macrophages were strongly related to SPARCL1 in cholangiocarcinoma, colon adenocarcinoma, rectum adenocarcinoma, and pancreatic adenocarcinoma.Conclusion: Our study found that SPARCL1 might work as a biomarker for prognosis and immune infiltration in pan-cancer analysis.