bluuebunny/crossref_metadata_2025_split huggingface dataset:
Al-Imam Ibnu Hazm Wa Juhuduhu Al-'Ilmiyyah
Authors: Fazlurrahman H. Lalu Muhamad 
Published: February 2022

One of the imams who had a lot of role and impact in the growth of islamic sciences is Imam Ibn Hazm, his name is not as famous as Imam Al-Syafi’i as the main reference for indonesian moslems the majority of them are followers of the Syafi’i madhhab, Ibn Hazm’s thoughts are like the madhhab adopted by him the Azzohiriyah School looks simple, literally and textual but if it is studied in more depth and more detail it turns out to have strong scientific arguments. Therefore studying his thoughts and the methode of Imam Ibn Hazm in concluding the conclusions of laws are very important in responding to various contemporary problems which are increasingly complex, with that motivation the researcher tries to present a scientific article about Imam Ibn Hazm his personal life, and his methods of his ijtihad which generally refuse analogy (qiyas) and consistently adhere to the texts of the al-qur’an and hadith and ijma’ or the consensus of the moslems. His thoughts and methods are seen to be different from the majority of other scholars who continue to make qiyas or analogies as a source of islamic law, but precisely for that reason the study of Ibn Hazm and his thoughts becomes interesting and important to do.
Keywords : Imam Ibn Hazm, the source of islamic law, textual.
Aesthetic dentistry as an integral component of facial aesthetics
Authors: Matthews‑Kozanecka Maja , Chomiak Anna 
Published: February 2022

With the appearance of the first signs of aging on the face, including wrinkles, we begin to think about our external appearance in terms of its aesthetics and attractiveness. The aesthetics of the face is one of the components of health, so in the process of evaluating the aesthetics of the face it is essential not to omit a very important aspect, namely the condition of the oral cavity and teeth. Therefore, when thinking about aesthetic medicine, it is worth consulting a dentist to assess the condition of the mouth, check the muscle tone, bone health, proper occlusion, missing teeth or tooth decay. Interdisciplinary dental treatment including restorative dentistry, periodontics, dental surgery, orthodontics, prosthodontics and sometimes maxillofacial surgery can be a prelude to facial aesthetic medicine treatment. A beautiful, aesthetic smile is not only a smile without signs of aging, but especially one resulting from healthy oral cavity.
Hubungan antara Self Compassion dengan Resiliensi pada Mahasiswa Tingkat Akhir
Authors: Oktaviani Mira , Cahyawulan Wening 
Published: February 2022

Penelitian ini bertujuan untuk mengetahui hubungan antara self compassion dengan resiliensi pada mahasiswa tingkat akhir. Penelitian ini menggunakan metode korelasi dengan pendekatan kuantitatif. Subjek dalam penelitian ini berjumlah 310 mahasiswa tingkat akhir Fakultas Ilmu Pendidikan Universitas Negeri Jakarta. Pengambilan sampel menggunakan Teknik accidental sampling. Alat pengumpul data berupa instrumen Skala Welas Diri (SWD) dan Connor-Davidson Resilience Scale (CD-RISC) Short version-10 item yang diadaptasi oleh peneliti. Hasil uji validitas menunjukkan semua butir pernyataan valid. Uji reliabilitas untuk variabel self compassion sebesar 0,962 dan untuk resiliensi 0,801 berada pada kategori sangat tinggi. Hasil penelitian menunjukkan bahwa terdapat hubungan positif antara self compassion dengan resiliensi pada mahasiswa tingkat akhir dengan koefisien korelasi 0,498 dan siginifikansi 0,000 (p<0,05).
Transverse Rectus Abdominis Muscle Flow-Through to Free Fibula Flap for Lumbar Spinal Reconstruction in a Pediatric Patient
Authors: Moores Neal G. , Luo Jessica , Pires Giovanna , Moss Whitney , Short Scott , Bollo Robert J. , Randall R. Lor , Agarwal Jayant P. 
Published: February 2022

Case:
A 7-week-old girl presented with a recurrent primitive myxoid mesenchymal tumor of infancy requiring extensive resection of lower back musculature, L3–S2 vertebral bodies, and left L5 nerve root. Reconstruction consisted of transverse rectus abdominis muscle (TRAM) flow-through to free fibular flap to reconstruct the bony defect and fill the soft-tissue void. One-year postoperative imaging revealed a well-incorporated fibula graft. At the 30-month follow-up, the patient can bear weight on the autograft while sitting upright, allowing for efficient ambulation with a wheelchair.

Conclusion:
TRAM flow-through to free fibular flap is an efficacious reconstructive method for a multilevel vertebral spinal defect in a pediatric patient.
Design of a Fuzzy Rule Based Expert System for Automatic Raga Selection for Cryptographic Applications
Authors: Pranav Prashant , Dutta Sandip 
Published: February 2022

Abstract
Strengthening the security of data and information of an organization or an individual is of utmost importance in the current scenario. Due to the increasing computing power of the intruder, the need for an emerging and new technique to secure the messages cannot be denied. The unbreakable of the future may be broken with some effort and time. We have proposed a new technique to secure the information which uses the employment of a Fuzzy Expert System in the Hindustani Music to produce encrypted sequences in the form of musical notes. These produced note sequences can be sent over the communication medium in the form of a piece of music. This work is basically an extension of our work proposed in [1]. We have simulated three Hindustani ragas viz. Yaman Kalyan, Bageshree and Malkuan with fuzzy rules to select a new raga for messages of different length.
Erythropoietin receptor is a risk factor for prognosis: a potential biomarker in lung adenocarcinoma
Authors: Feng Yangchun , Zhang Yajing , Wang Senyu , Han Songtao , Huang Yaoyao 
Published: February 2022

Abstract
Background: Lung cancer has the highest mortality rate of all cancers, and LUAD' s survival rate is particularly poor. Erythropoietin receptor (EPOR) can be detected in lung adenocarcinoma (LUAD), however, the expression levels and prognostic value of EPOR in LUAD are still unclear.Methods: Multiple bioinformatics databases, immunohistochemistry and clinicopathological data of 92 LUAD patients between January 2008 and June 2016 were used to explore the EPOR expression, gene mutations affecting EPOR expression, the correlation of EPOR expression with prognosis, immune microenvironment and so on. All statistical analyses were performed in the R version 4.1.1.Results: The EPOR mRNA expression in LUAD tissues was possibly downregulated compared with that in normal lung tissues, but the EPOR protein expression in LUAD tissues was higher than that in paired normal lung tissues. Mutations in five genes including DDX60L, resulted in downregulation of EPOR expression, mutations in 10 genes including C1orf168, resulted in upregulation of EPOR expression. The KM Plotter and PrognoScan databases consistently concluded that EPOR was associated with prognosis in LUAD patients. Our clinicopathological data showed that high EPOR expression was associated with poorer OS (29.5 vs 46 months) and had a good predictive ability for 5-year survival probability. Conclusions: EPOR expression might be downregulated at the mRNA levels and significantly upregulated at the protein levels in LUAD, which showed that the mRNA and protein levels of EPOR are inconsistent.The high expression of EPOR was associated with poor prognosis and is expected to be a potential new prognostic marker for LUAD.
DEPINV：A WeChat Applet for Online Intervention of Depression Based on Accept Cognition Theory
Authors: Xu Ronghua , Zhang Qingpeng , Zou Honglu , Tan Sidie , Zhu Lifan 
Published: February 2022

Abstract
Background: Studies have shown that the phenomenon of fetal malformations can cause serious psychological problems and even depressive symptoms of pregnant women during their perinatal period. Psychological studies have shown that involving these women into appropriate interventions and treatments can effectively alleviate their depressed symptoms. With the prevalence of mobile technologies and online social networks, practitioners and researchers have been dedicating to move the offline intervention strategies to online platforms for the treatment of depression caused by fetal malformations.System Design: We design an online DEPression INterVention system (DEPINV), suitable for the online intervention of depressed woman suffering from fetal malformations. There are three main features in the design of DEPINV. First, it intends for the effective coordination and interaction among three types of user roles in order to reach a tripartite synergistic therapy effect. Second, it focuses on the assessment and monitoring of users’ psychological state, and the Accept Cognition Theory (ACT) is introduced into the design of the system for the intervention. Third, various communication channels are provided to assist users’ coordination and ACT-based intervention. System Implementation: To make the access easy and flexible, we adopt the WeChat applet as the development and deploying technical framework. Therefore, DEPINV is a WeChat applet that can be accessed by simply scanning the Quick Response (QR) code. It cooperates three types of users, the healthcare providers, depressed women and their family members. That is, DEPINV helps healthcare providers to maintain and manage the psychological states of depressed women with the involvement of their family members. There are six successive stages in the core function of the ACT-based intervention and each target for the accomplishment of one specific psychological state. Through the comprehensive management of treatment procedure, DEPINV applet helps healthcare providers record and monitor the dynamic change of patients' affections. To cope with the negative emotions of depressed women, various channels of information support, social support and emotional support are also provided for instant communication between healthcare providers and family members.Conclusion: The DEPINV applet provides effective online interventional strategies and treatments for depressed women with the help of both healthcare providers and their family members. When more interventional features and functions are included, it is necessary to extend the applet into a mental health app.
High sensitivity liquid analyte filled photonic crystal fiber refractive index sensor covered by symmetrical metalnano-films based on surface plasmon resonance
Authors: Fan Zhenkai , Qin Jianye , An Guochen , Fan Yuqiu , Zhang Yinping , Zhang Xiuqing , Liu Haishan , Chu Shichao 
Published: February 2022

Abstract
A high sensitivity of photonic crystal fiber (PCF) with a tunableliquid core refractive index sensor based on surface plasmon resonance (SPR) induced bythe symmetric metal films is proposed in this paper. The SPR excitation materials are chose as gold and silver. The transmission characteristics and sensing performance of the SPR-PCF sensor with different geometrical parameters were analyzed by using finite element method (FEM) and Maxwell equation. The final results show that when thediameter of the central hole is 1.6µm and the thickness of the gold film is 40nm, the SPR occurs at the wavelength of 1400nm, and the confinement loss can reach 17398dB/m. The average sensitivity of the SPR-PCFsensor can reach 7200nm/RIU, and the linear fitting constant is R2=0.99959, which is expected to have important applications in the direction of liquid refractive index detection.
The association between intake of whole grain, refined grain, fast food and carbonated drinks with depression and quality of life in Iranian adolescent girls
Authors: Sangouni Abbas Ali , darabi zahra , Ghayour-Mobarhan Majid , Mazidi Mohsen , Lane Katie E , Khayyatzadeh Sayyed Saeid 
Published: February 2022

Abstract
Background: We evaluated the association between fast food, whole grain, refined grain and carbonated drink consumption with depression and QoL in Iranian adolescent girls.Methods: In this cross-sectional study, 733 adolescent girls were included from Mashhad and Sabzevar cities in northeastern Iran. The Beck Depression Inventory (BDI) and SF-12v2 questionnaire were used to assess depression and QoL, respectively. A valid and reliable food frequency questionnaire was used to obtained dietary intakes of the study participants. To explore the association between intake of food groups and depression and QoL, we used linear and logistic regression in crude and adjusted models.Results: There was a signiﬁcant decreasing trend in the odds of poor QOL and depression across increasing quartile intake of whole grain; but, there was no linear relationship between whole grain intake with depression and QoL score. In addition, subjects in the highest quartile of carbonated drink consumption had higher odds of poor QoL compared to the first quartile (OR: 1.33; 95% CI: 1.00–2.32, P = 0.04). We found a positive association between intake of fast food and depression score (β= 0.09). Intake of fast food was inversely associated with QoL score (β= -0.081). However, there was no significant relationship between intake of refined grains and carbonated drinks with depression, and between whole grain and refined grain intake with QoL.Conclusions:We demonstrated an inverse association between fast food intake with depression and QOL. To better conclude, further studies evaluating the association of various food groups with depression and QoL.
Glutamine and norepinephrine in follicular fluid synergistically affect the antioxidant capacity of human granulosa cells and the outcome of IVF-ET
Authors: Wang Lulu , Zhou Chengliang , Sun Junyan , Zhang Qiuwan , Lai Dongmei 
Published: February 2022

Abstract
Background: An increasing number of studies have demonstrated that changes in metabolic levels in follicular fluid are directly related to oocyte maturation, fertilization, the quality of embryo and pregnancy rates. However, whether the intra-follicular neurotransmitters affect the function of granulosa cells and the outcome of in vitro fertilization and embryo transfer (IVF-ET) is not clear.Methods: Human follicular fluid and cumulus granulosa cells (GCs) were harvested from large follicles obtained from 27 patients undergoing IVF. Neurotransmitters and steroid hormones in follicular fluid were measured through liquid chromatography–tandem mass spectrometry (LC-MS/MS) and high-performance liquid chromatography–mass spectrometry (HPLC-MS/MS) respectively. Based on the content of Glutamine (Gln) in follicular fluid, the samples were divided into two groups: high Gln level group and low Gln level group. The expression of proliferation-, steroidogenesis- and antioxidant-related genes in GCs was detected by qRT-PCR. In vitro experiments, KGN cells were cultured with or without Gln and NE followed by western blotting to detect PCNA and IDH1 expression. EdU staining and ELISA were conducted to evaluate GCs proliferation and measure the contents of 17 b-estradiol (E2) and progesterone (Prog) in the conditioned medium. Primary and secondary outcomes were the number of mature and retrieved oocytes, and the ratio of high quality embryos, respectively.Results: Gln and norepinephrine (NE) were abundant neurotransmitters in follicular fluid. The contents of Gln and NE in follicular fluid exhibited a significantly positive correlation. The contents of Gln and NE in follicular fluid affected the function of granulosa cells, including their proliferative potential, E2 production and antioxidant capacity. Moreover, the concentrations of Gln and NE in follicular fluid showed significantly positive correlation with isocitrate dehydrogenase 1 (IDH1) expression in GCs. Importantly, the increased Gln and NE in follicular fluid partially affected the quality of embryonic development by regulating IDH1 expression in GCs. In vitro studies further demonstrated that Gln and NE played synergistically function in improving GCs proliferation and increasing the E2 production by upregulating IDH1 expression.Conclusions: These data demonstrate that neurotransmitter metabolic levels in follicular fluid affect the function of cumulus GCs. As important neurotransmitter metabolites, Gln and NE play significant roles in promoting GCs proliferation and increasing E2 production in granulosa cells. In addition, intrafollicular Gln and NE could upregulate the expression of the antioxidative gene IDH1 in cumulus GCs, which could be a good predictor for selecting optimal quality oocytes and evaluating the quality of embryonic development.
The difference of gut microbiome in different biliary diseases in infant before operation and the changes after operation
Authors: sun xinhe , Cai Yaoyao , Dai Wenwen , Jiang Weiwei , Tang Weibing 
Published: February 2022

Abstract
Background
Evidence supports an association between cholestatic liver disease and changes in microbiome composition. Nevertheless, the identification of this special type of biliary atresia from non-biliary atresia cholestasis is still a major clinical difficulty. The purpose of this study is to compare the differences in the composition of gut microbiome between infants with biliary atresia and infant with non-biliary atrestic cholestasis, to find new ways to identify and diagnose these two diseases early, to understand the influence of the presence or absence of bile on the composition of the gut microbiome in infants with cholestasis.
Methods
Using 16S rDNA gene sequencing technology to analyze the intestinal flora of the participants.
Results
In terms of diversity, there is an obvious structural separation in the intestinal microbiota of the BA group and the CD group, and this structural separation also exists in the comparison between the two groups before surgery. Species analysis demonstrated that the two groups showed an increase in Proteobacteria and Firmicutes before surgery, and the relative abundance of pathogens such as Shigella, Streptococcus, Klebsiella, etc. increased, probiotics such as Bifidobacteria and Lactobacillus decreased, but the relative abundance of each genus was different between groups. It was found that Enterococcus, Ralstonia, Nitriliruptoraceae, etc. were differentially enriched in the BA group, the CD group are mainly enriched in Veillonella, Clostridium_sensu_stricto_1 and Lactobacillus. Functional analysis of the groups showed that the BA group mainly focused on the processes of energy release processes, and the CD group mainly focused on the biosynthesis of amino-acids to consume energy.
Conclusions
The composition of intestinal flora is different between biliary atresia and non-biliary atretic cholestasis. Enterococcus, Ralstonia, etc. may become biomarkers for the identification and diagnosis of both.
Paeoniflorin Ameliorates Colonic Fibrosis In Rats With Post-Infectious Irritable Bowel Syndrome By Inhibiting The Leptin/Leprb Pathway
Authors: Cao Di , Wu Yaning , Zhang Kunli , Zheng Yijun , Tian Yaqing , Xu Qixiang , Liu Ping , Zhou Huihui , Liu Xiaoping , Zheng Yongqiu , Wang Fengyun 
Published: February 2022

Abstract
Post-infectious irritable bowel syndrome (PI-IBS) is a highly prevalent gastrointestinal disorder associated with immune dysregulation and depression- and anxiety-like behaviors. The active ingredient of Paeoniae Radix called paeoniflorin (PF) was previously found to prevent the symptoms of PI-IBS. However, there is limited information on the effects of PF on the intestinal function and depression- and anxiety-like symptoms in PI-IBS animal models. Here, we aimed to determine the effects of PF treatment on the symptoms of PI-IBS in a rat model. After the experimental period, the PI‑IBS rats presented decreased body weight and increased fecal water content, which coincided with the elevated leptin levels and heightened depression- and anxiety-like behaviors (e.g., low sucrose intake, less frequency in the center areas during open field test). However, the PF treatment ameliorated these observed symptoms. Furthermore, PF not only inhibited leptin/LepRb expression, but also reduced the PI3K/AKT phosphorylation and brain-derived neurotrophic factor (BDNF) expression in PI-IBS rats. Notably, co-treatment with leptin (10 mg/kg) reduced the effects of PF (20 mg/kg) on colonic fibrosis, leptin/LepRb expression, and PI3K/AKT activation. Therefore, our findings suggest that leptin is targeted by PF via the leptin/LepRb pathway, consequently ameliorating the symptoms of PI-IBS. Our study also contribute novel insights for elucidating the pharmacological action of PF on gastrointestinal disorders and may be used for the clinical treatment of PI-IBS in the future.
Biological Removal of Groundwater’s Nitrate under Sterile and Non-sterile Soil Conditions (Lab Experiment and Simulation)
Authors: Samani Farideh Ansari , Tabatabaei Sayyed-Hassan , Abbasi Fariborz , Nazem Zohreh , Rabiee Mohammad 
Published: February 2022

Abstract
Nitrate is potentially harmful in an aquatic environment however it can be converted into more dangerous forms by microbial activities. In this research, we tested the efficiency of nitrate removal by using a denitrification bed (DB) containing in sterile soil (SS) and non-sterile soil (NSS) media. A Marriott column and a Plexiglas column filled with a clay loam soil were used as the water resource and DB, respectively. Potassium nitrate used to make different nitrate concentrations including 24, 50 and 100 (mg l-1). The nitrate was injected up to ten pore volumes (PV), when the soil was sterile, only active surfaces within the soil matrix acted as an adsorbent. The number of bacteria and the bacteria growth was investigated at the end of each experiment. The solute transfer parameters were estimated by using soil hydraulic parameters at HYDRUS model. As result, the growth of bacteria and the concentration of pollutants in the output of the column decreased in SS media. In the NSS with a concentration of 100 mg nitrate, the number of bacteria increased to the highest, 80000 bacterial number. The presence of rival anions in the solution has a negative impact on reducing the adsorption rate and removal of nitrate. In NSS with nitrate concentration of 24 (mg l-1), the removal nitrate efficiency nearly 99.5 (%). There was a significant difference between nitrate concentration of the SS and NSS conditions (p<0.05). The value of the diffusion coefficient is 4.99 (cm). Sensitivity analyses demonstrated that saturated hydraulic conductivity had the greatest effect on the variations of nitrate concentration. Besides, the correlation coefficient between simulated values and observed values by the HYDRUS-1D model varied between 0.90 and 0.99.
The Ultra-high Hg0 Adsorption Capacity Modified by Selenium
Authors: Liu Ye , Ma Chenglong , Zhou Jiacheng , Zhu Lin , Cao Limei , Yang Ji 
Published: February 2022

Abstract
Activated carbon was one of the main adsorptions utilized in elemental mercury (Hg0) removal from coal combustion flue gas. However, the high cost and low physical adsorption efficiency of activated carbon injection (ACI) limited its application. In this study, an ultra-high efficiency catalyst sorbent-Sex/Activated carbon (Sex/AC) was synthesized and applied to remove Hg0 in the simulated flue gas, which exhibited 120 times outstanding adsorption performance versus the conventional activated carbon. The Sex/AC reached 17.98 mg/g Hg0 adsorption capacity at 160 °C in a pure nitrogen atmosphere. Moreover, it maintained an excellent mercury adsorption tolerance at the NO and SO2 conditions in a bench-scale fixed-bed reactor. Characterized by the multiple methods, including BET, XRD, XPS, and the DFT calculation, we demonstrated that the ultrahigh mercury removal performance was driven from the activated Se species in Sex/AC. Chemical adsorption was the main reason for Hg0 removal: Selenium on the surface of AC would capture Hg0 in the flue gas to form an extremely stable substance-HgSe, avoiding subsequent Hg0 released. Additionally, the oxygen-containing functional groups in AC and the higher BET areas promote the conversion of Hg0 to HgO. This work provided a novel and highly efficient carbon-based sorbent -Sex/AC to capture the mercury in coal combustion flue gas.