bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lithostratigraphy, Lithogeochemistry, and Tectono-Magmatic Framework of the ABM Replacement-Style Volcanogenic Massive Sulfide (VMS) Deposit, Finlayson Lake District, Yukon, Canada
Authors: Denisová Nikola , Piercey Stephen J. 
Published: July 2022

Abstract
The Upper Devonian ABM deposit is a bimodal-felsic, replacement-style volcanogenic massive sulfide (VMS) deposit within the Finlayson Lake district in Yukon, Canada. The deposit is hosted by predominantly felsic volcanic rocks of the upper Kudz Ze Kayah formation that were deposited in an active back-arc basin in three sequences consisting of interbedded felsic volcaniclastic rocks and argillites, and felsic lava flows and domes, and felsic and mafic sills. The felsic rocks fall into two groups, Felsic A and Felsic B (FA and FB), based on immobile elements and their ratios. Relative to the FB group, the FA group has high Zr concentrations (&gt;550 ppm) and generally higher contents of high field strength elements. The FA/FB chemostratigraphy roughly coincides with the lithostratigraphic sequences. Sequence 2 hosting the mineralization consists of FB felsic rocks; the hanging-wall Sequence 3 and footwall Sequence 1 felsic rocks have FA signatures. An argillite lens, recording a period of volcanic quiescence, occurs at the upper contact of Sequence 2.
From reconstruction of the basin architecture, two sets of synvolcanic faults are inferred. The synvolcanic faults were interpreted based on thickness changes of volcanosedimentary units and the distribution of coherent rocks. During breaks in volcanism, synvolcanic faults acted as conduits for upwelling hydrothermal fluids, which were diverted laterally into unconsolidated volcaniclastic rocks and formed the replacement-style VMS mineralization. Although the mineralized lenses are hosted by FB felsic rocks, their replacement-style nature implies that the mineralizing processes occurred during the break in volcanism and were genetically associated with the overlying FA felsic volcanic rocks.
Inclusión en Alemania: una visión comparada de los estados federales “Länder"
Authors: Farrero Magdalena Riusech 
Published: July 2022

¿Cómo ve y define Alemania el concepto de inclusión? Este concepto se basa en dos principios fundamentales, por un lado, los valores humanos y por otro, el reconocimiento de la Diversidad en la educación. Este cambio de visión de pasar de la heterogeneidad a la diversidad conlleva una transformación en la manera de afrontar este concepto. Ya no se ve a la persona con discapacidad o con diferencias importantes como grupo sino como individuo. Este cambio de visión requiere también un cambio en la estructura educativa. Me permito hacer una breve reseña histórica, que considero fundamental para comprender la evolución hasta la situación actual de este concepto. En Alemania, históricamente las diferencias por discapacidad o por dificultades educativas han significado no sólo exclusión sino también separación en escuelas especiales, así pues, el tándem exclusión y separación han ido de la mano. La conferencia de la Unesco en Salamanca sobre el tema “Pedagogía para las necesidades: acceso y calidad” significó el hito para poner en práctica el sistema educativo inclusivo. El siguiente paso decisivo tuvo lugar en 2006 “la convención de las Naciones Unidas sobre los derechos humanos de las personas con discapacidad y su inclusión en el sistema educativo” principalmente en su artículo 24. Es en 2010 cuando la “Kultusministerkonferenz” (KMK) basándose en la convención de las Naciones Unidas publica un acuerdo sobre los aspectos pedagógicos y legales para la implementación de los derechos de las personas con discapacidad. Un año más tarde ve la luz un acuerdo también de la KMK sobre la educación inclusiva en las escuelas de los niños y jóvenes con discapacidad. En la República Federal Alemana son los Estados Federales “Länder” los que tienen competencia en materia de educación. A partir de este momento cada Land establece su propia ley, a veces más avanzada y con implementación más rápida y otras veces, al contrario. Llegados a este punto presentaré un estudio comparativo de las leyes y de los avances más o menos rápidos en este campo de cada uno de los estados federales. La brevedad de extensión de este resumen no me permite entrar en más detalles, ya que si lo hiciera podría caer en el riesgo de sesgar algunos datos por falta de espacio. Como ejemplo añado un mapa del país con los datos de 2017 y publicado por la Agencia Federal de Estadística. Partiendo de este estudio comparativo pretendo llegar a unas conclusiones sobre la situación actual de la inclusión en los distintos Estados Federales de Alemania.
Fluoxetine misuse by snorting in a teenager: a case report
Authors: Khoodoruth Mohamed Adil Shah 
Published: July 2022

Introduction Self-harm and substance use disorders (SUD) are leading causes of Years of Life Lost (YLLs) among young people aged 10-24 years as per the Global Burden of Disease (GBD) Study 2019. The co-occurrence of these conditions can complicate the clinical picture and often poses a challenge to child and adolescent mental health professionals. Moreover, substance use by adolescents, due to the probable physical, legal and psychiatric complications, has the potential to progress into full-blown SUD in adolescence or adulthood. Case Report We present the case of a 15-year-old female with a history of multiple serious suicidal attempts and drug use disorders who misused fluoxetine as part of maladaptive coping. Selective serotonin reuptake inhibitors (SSRIs) are not known to be commonly abused drugs, let alone sniffed or snorted. To the best of our knowledge, this is the first reported case of an adolescent snorting the drug fluoxetine (SSRI). Conclusion This case highlights three main aspects for child and adolescent mental health professionals. First, the importance of screening for recreational drugs misuse in general, including fluoxetine, in a comprehensive assessment of a young person with coexisting substance misuse issues or its history. Second, ‘comorbidity is the rule rather than the exception’ in adolescents with SUDs. Third, the possible benefit of quetiapine in managing emotional dysregulation in a high-risk adolescent with traits of an emerging borderline personality disorder.
KEBIJAKAN KETAHANAN PANGAN DAN LITERASI PANGAN MASYARAKAT (Studi Penelitian Tentang Literasi Pangan Mendukung Ketahanan Pangan di Kota Semarang)
Authors: Widyastomo Rahmad Purwanto 
Published: July 2022

<p align="center"><strong>Abstra</strong><strong>k</strong></p><p>Tujuan penelitian tentang ketahanan pangan dan pentingnya literasi pangan masyarakat adalah mendskripsikan ketahanan pangan di Kotra Semarang berdasarkan dokumen perencanaan daerah dan kebijakan ketahanan pangan dan gizi telah dilaksanakan berdasarkan kewenangan pemerintah daerah. Konsumsi bahan pangan pokok penduduk sangat tergantung pada beras (produksi hanya memenuhi 15% dari kebutuhan penduduk) dan memerlukan dukungan dari kabupaten sekitar. Demikian pula bahan pangan sayur mayur, buah-buahan, daging dan ikan lebih besar dari kabupaten sekitar. Pemahaman masyarakat tentang pangan beragam semakin baik dan memerlukan dukungan perguruan tinggi, kalangan dunia usaha dan media massa mengenalkan pangan beragam, piring panganku dan perilaku hidup bersih dan sehat melalui Gerakan Masyarakat Sehat (Germas) dan kelembagaan Kota Sehat semakin penting peranannya dalam masyarakat.</p><p><em>Kata kunci : kebijakan ketahanan pangan, pangan beragam dan gizi </em></p><p align="center"><strong><em>Abstract</em></strong></p><p><em>The purpose of research on food security and the importance of community food literacy is to describe food security in Kotra Semarang based on regional planning documents and policies on food security and nutrition that have been implemented under the authority of the local government. Consumption of staple foods of the population is highly dependent on rice (production only meets 15% of the population's needs) and requires support from the surrounding district. Likewise, food ingredients for vegetables, fruits, meat and fish are bigger than the surrounding districts. The public's understanding of diverse food is getting better and requires the support of universities, the business community and the mass media to introduce diverse food, my food plate and clean and healthy living behavior through the Healthy Community Movement (Germas) and the Healthy City institution whose role is increasingly important in society.</em></p><p><em> </em></p><p><em>Keywords: food security policy, diverse food and nutrition</em></p>
Petróleo, empresas e gestão do território: uma análise sobre o mercado de combustíveis no município de Serrinha
Authors: Silva John Wolter Oliveira , Léda Renato Leone Miranda 
Published: July 2022

O presente artigo tem como objetivo analisar o processo de gestão territorial realizado pela atuação das empresas Postos de Revenda de Combustíveis (PRCs) no município de Serrinha/BA. Trata-se de um recorte da pesquisa intitulada “Estratégias e práticas espaciais das distribuidoras e postos de combustíveis como agentes de gestão do território em escala local – O caso do município de Serrinha/BA”, desenvolvida no âmbito do Curso de Geografia do Departamento Educação da Universidade do Estado da Bahia, Campus XI – Serrinha. Os PRCs representam uma parcela do conjunto de atividades ligadas ao setor do petróleo, se distribuem por todo o território nacional formando uma densa rede de estações de abastecimentos de veículos automotores, interconectados com as bases de distribuição regionais das principais empresas, como BR, Ipiranga, Raízen, Alesat, dentre outras. O arcabouço teórico-metodológico desta investigação ampara-se na perspectiva da abordagem qualitativa, sem excluir, necessariamente, o levantamento e análise de dados quantitativos, utilizando-os de modo complementar; com a discussão de pressupostos da Ciência Geográfica como Gestão do Território, Redes Geográficas e Circuitos Espaciais Produtivos e Círculos de Cooperação numa leitura de caráter geográfico-econômico aplicada na atuação empresas revendedoras de combustíveis na gestão do território no município de Serrinha/BA. Os procedimentos adotados foram a produção de mapeamento da configuração espacial dos PRCs de Serrinha/BA, pelo exercício de análise de imagens e da pesquisa de campo com visita aos 26 PRCs do município para aplicação de questionário e realização de entrevistas com gerentes e responsáveis, além do registro fotográfico da área dos postos e adjacências. Portanto, este trabalho, demonstrou o emaranhado de postos e distribuidoras que atuam nesta face do setor do petróleo no município, apresentando um potencial de disputas concorrenciais de preço e qualidade dos produtos e serviços, com tendência de expansão dessas relações ao considerarmos as transformações socioespaciais que um município tende a vivenciar no avançar do tempo histórico-geográfico.
Free Surface Measurements of Large-Scale Breaking Transom Waves using Quantitative Visualization
Authors: Beale Kristine L.C. , Fu Thomas C. , Wyatt Donald C. , Walker Don C. 
Published: July 2022

Experimental observations support the physical understanding of breaking ship waves, a challenging multiphase flow regime. The Quantitative Visualization (QViz) measuring technique allows non-uniform flows which are typically difficult to characterize.
Advanced image processing algorithms have been developed to allow the standard QViz approach to obtain detailed, time-varying free surface elevations of the waves generated behind a transom-stern. The resulting surface roughness and free-wave spectral content provide a method of breaking-wave region assessment, as well as guidance and verification for numerical models.
A Directional Wave Array Using Ultrasonic Sensors
Authors: Fullerton Anne , Fullerton Brian , Fu Thomas 
Published: July 2022

A typical approach to determining wave direction is to assume that the sea surface is made up of several sinusoidal waves of various frequencies and directions. One method to determine wave direction as a function of frequency is to use an array of time-series point measurements of water elevation. These multi-element arrays can either be linear or polygonal, and utilize phase, time and path differences to determine wave direction. Typically, pressure gages or capacitance wave probes are used in a directional wave array, however, recently at the Naval Surface Warfare Center, Carderock Division, a directional wave array was employed using five ultrasonic level sensors in an array to quantify wave direction in the Maneuvering and Seakeeping basin (MASK). Two methods were then used to calculate wave direction, a phase/path/time difference method of Esteva which yields a mean direction for each frequency bin, and the Maximum Likelihood Method (MLM), which yields a directional spectrum for each frequency bin. Testing in the MASK was performed to assess the feasibility of using the array on a moving vessel to measure directional seas in the field.
The sensors' sampling rate was set at 20 Hz and the five sensors were set up in "slave-master" mode, with the “master” driving the four “slaves” to sample concurrently. This method helped to reduce cross-talk between the sensors and their subsequent dropouts and spikes. Data was collected using LabView software with custom written real-time analysis in MATLAB. Wave direction was measured with regular and irregular waves, with unidirectional and bi-directional systems ninety degrees apart. Tests were performed with the array in a stationary position, as well as with forward motion and simulated pitch and roll motions to assess the potential of using the array on a moving vessel. Results with the stationary array from the basin are good, with the array correctly measuring regular waves of a single frequency from two directions, as well as irregular waves from two directions. Results from the system undergoing motions have increased variability.
Hull Forms with Low Cruise Speed Resistance and High Speed Dynamic Stability-Experiments and Computations
Authors: Ranzenbach Robert , Bowles Jeffrey 
Published: July 2022

The performance of three different shaped hulls was evaluated by experiments and computations to identify a hull form that provides low calm water resistance at cruise speed while remaining dynamically stable at high speed. The target cruise speed was at a length Froude number of 0.45, and the target high speed was at a length Froude number of 1.0.
The three hybrid hulls utilized a common round bilge after body shape derived from the NPL systematic series mated to different bow shapes:
_ Hull #1- Double Chine
_ Hull #2- Round Bottom with Spray Rail
_ Hull #3- Single Chine
The 1:20 model-scale experiments were performed at the SSPA Towing Tank to evaluate the calm water resistance and dynamic stability characteristics of the three hulls. Two displacements and up to three Longitudinal Center of Gravity positions were evaluated for each model. A computational study using STAR-CCM+, a Reynolds Averaged Navier-Stokes solver, was performed to investigate a limited number of the test conditions evaluated at SSPA. The computations included time-accurate runs designed to duplicate the dynamic stability testing methodology utilized in the experiments. Model #3- Single Chine was found to represent the lowest drag of the candidate hull forms at cruise speed while retaining dynamic stability at high speed. The calm water-resistance of this hybrid hull shape at cruise speed was found to be within 8.5% of a purely round bilge hull form as represented by the NPL systematic series.
Análisis crítico de la violencia estetizada. Caso del colectivo Los Ingrávidos en México
Authors: Martínez Morales María 
Published: July 2022

This paper deals with a study of experimental cinema as a political action based on an approach to the artistic creation process of the Los Ingrávidos collective. The work analyzes the methodology approached by the group to delve into the process of creating the work Sangre Seca and Trasmision/Desencuadre, with the aim of understanding the social and political articulation through the experimental cinema of a group that emerges in the face of situations of Live violence in Mexico City. For this, we approach a study of the image of an emotion cinema that works with archive material for the construction of counter-narratives, images that challenge the information offered by the media offering other readings. As a result of the study, we expose arguments that claim the formative power of the image to articulate alternative actions in cases of aestheticized violence.
El presente trabajo aborda un estudio del cine experimental como acción política a partir de una aproximación al proceso de creación artística del colectivo Los Ingrávidos. El trabajo analiza la metodología abordada por el colectivo para adentramos en el proceso de creación de la obra Sangre Seca y Trasmisión/Desencuadre, con el objetivo de comprender la articulación social y política a través del cine experimental de un colectivo que emerge ante las situaciones de violencia vividas en la ciudad de México. Para ello, nos acercamos a un estudio de la imagen de un cine de agitación que trabaja con material archivo para la construcción de contra-relatos, imágenes que desafían la información ofrecida por los medios de comunicación ofreciendo otras lecturas. Como resultado del estudio, exponemos argumentos que reclaman la potencia formadora de la imagen para articular acciones alternativas ante casos de violencia estetizada.
Textiles maternos: una revolución reflexiva de las mujeres latinoamericanas frente al patriarcado social
Authors: León Río Belén 
Published: July 2022

In this article we want to make known the creative and organizational process of activist art of Latin American women in whose experimental projects textile materials and techniques would be protagonists as a means of showing society their insubordination to the power of patriarchy and social injustice. These women who silently embroider in the streets the names of their murdered companions, who collect the garments of those disappeared migrants who plot fictions from the creative in search of their interiority, would focus our attention through these maternal textiles as emotional symbols impregnated by the energy of the new contemporary martyrs that are made visible through their artistic actions and the community of volunteers committed to these projects. They, like the great goddesses, would carry the cloak, the veil and in their hands the thread, the spindle and the distaff, thus presiding over the birth of forms, the passing of time and the fertile power of the goddess as a symbol of creation and of social transformation.
En este artículo queremos dar a conocer el proceso creativo y organizativo del arte activista de las mujeres latinoamericanas en cuyos proyectos experimentales serían protagonistas los materiales y técnicas textiles como medio de mostrar a la sociedad su insumisión ante el poder del patriarcado y la injusticia social. Estas mujeres que bordan en silencio en las calles los nombres de sus compañeras asesinadas, que recogen las prendas de aquellos migrantes desaparecidos que traman ficciones desde lo creativo en busca de su interioridad, focalizarían nuestra atención a través de estos textiles maternos como símbolos emotivos impregnados por la energía de los nuevos mártires contemporáneos que se hacen visibles a través de sus acciones artísticas y la comunidad de voluntarias comprometidas con estos proyectos. Ellas al igual que las grandes diosas portarían el manto, el velo y en sus manos el hilo, el huso y la rueca presidiendo así el nacimiento de las formas, el devenir del tiempo y el poder fecundo de la diosa como símbolo de creación y de transformación social.
Surface cysteine to serine substitutions in IL-18 reduce aggregation and enhance activity
Authors: Saetang Jirakrit , Roongsawang Niran , Sangkhathat Surasak , Voravuthikunchai Supayang Piyawan , Sangkaew Natnaree , Prompat Napat , Srichana Teerapol , Tipmanee Varomyalin 
Published: July 2022

Background
Interleukin-18 (IL-18) is prone to form multimers resulting in inactive aggregates, making this cytokine unstable for clinical use. Therefore, mutations have been introduced into recombinant IL-18 to overcome this issue.

Methods
To prevent the formation of disulfide bonds between the IL-18 molecules, multiple mutations targeting surface cysteines (C38, C68, C76, and C127) were introduced into our previously modified human IL-18 double mutant E6K+T63A (IL-18 DM) by direct gene synthesis. The open reading frames of IL-18 wild-type (WT), IL-18 DM, and IL-18 multiple mutant E6K+T63A+C38S+C68S+C76S+C127S (IL-18 DM1234) were inserted in the pET28a expression vector and transformed into Escherichia coli Rosetta2 (DE3) pLysS cells for protein production. The inclusion bodies of WT and mutated IL-18 were extracted by sonication and refolded by stepwise dialysis using 8 M urea as the starting concentration. The refolded IL-18 proteins were tested for aggregation using the ProteoStat protein aggregation assay. Their activity was also investigated by treating NK-92MI cells with each IL-18 at concentrations of 75, 150, and 300 ng/ml with 0.5 ng/ml of human IL-12 and interferon-gamma (IFN-γ) levels in the supernatant were evaluated using ELISA. The structure of modified IL-18 was visualized using molecular dynamics (MD) simulations.

Results
IL-18 DM1234 exhibited the lowest aggregation signal, approximately 1.79- and 1.63-fold less than that of the WT and IL-18 DM proteins. Additionally, the IFN-γ inducing activity of IL-18 DM1234 was about 10 and 2.8 times higher than that of the WT and IL-18 DM, respectively. MD simulations revealed that binding site I of IL-18 DM1234 was altered mainly due to surface cysteine replacement with serine (C-to-S substitution). This is the first report showing that C-to-S substitutions in IL-18 improved its activity and stability, suggesting the use of this modified IL-18 for medical purposes in the future.
Consumer Satisfaction of Marketplace Users in Indonesia
Authors: Cahyono Tomy Dwi , Ananda Nova Adhitya 
Published: July 2022

Aims: The main goal of marketing management today is customer satisfaction. It is crucial to know consumer satisfaction because satisfied consumers will tend to buy the product in the future. In addition, satisfied consumers will also become the company's promotional staff because they will recommend the company's products to their friends and family. This study highlights consumer satisfaction in online shopping, which is currently highly developed due to technological advances. Therefore, the researcher considers it essential to know what factors can make consumers feel satisfied so that later they can increase product sales on the shopee marketplace. This study uses three variables to explain consumer satisfaction: discounts, product quality, and purchase decisions. The reason these variables are used is because these variables are better able to explain consumer satisfaction. After making a purchase at Shopee, consumers will feel satisfied or not.
Study Design: One hundred seventy-five active shopee marketplace users in the Sumbawa district are the sample in this study. In this study using a purposive sampling technique. The research hypothesis was answered using a structural equation modeling analysis tool based on partial least squares. This study uses the Sobel test to justify whether the purchase decision is an intervening variable.
Results: These three variables, after being investigated, have a direct influence on consumer satisfaction. The results of the study provide information that shopee consumer satisfaction is achieved through discounts, product quality and purchase decisions. The more satisfied consumers are caused by the big discounts given and good product quality.