bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Vipera berus berus and Vipera berus nikolskii Venom on Proteolytic Balance in the Tissue of the Adrenal Glands and Testicles of Rats
Authors: Palamarchuk Mariia , Niyazmetov Timur , Halenova Tetiana , Raksha Natalia , Maievskyi Oleksandr , Dzevulska Iryna , Zaichko Kateryna , Savchuk Olexii , Ostapchenko Ludmila 
Published: December 2022

Background:

Vipera berus berus and Vipera berus
nikolskii are the most widely spread Old World vipers in Europe, who contribute to almost all cases of snakebites on this territory. Their venoms are known to cause proteolysis, thrombocytopenia, induction of neurotoxicity and haemorrhage, among which proteolytic action constitute to the possible affection of all metabolic pathways in the targeted organs and in the whole organism.

Methods:
The influence of the viper venoms on the adrenal glands and testicles of injected rats was studied through the analysis of the concentration of proteins (Bradford method), evaluation of the qualitative protein profile (disc electrophoresis), distribution of active proteolytic molecules in the studied tissues (enzyme electrophoresis) and estimation of the appearance of low molecular weight molecules.

Results:
The decline of the number of the total protein, the alterations of the protein composition and the enzymatic redistribution were declared to appear in these organs under the action of the studied venoms proving the assumption of the proteolysis activation. Whereas, the increase in the level of low molecular weight molecules has emerged showing the onset of the state of toxicity.

Conclusion:
the study of the influence of the V. berus berus and V. berus nikolskii venoms on the protein balance of adrenal glands and testicles was performed, showing the impact on the amount of total proteins, its redistribution and connection with toxicity and proving the onset of pathological process.
Serum Iron Level and Methemoglobin Concentration among Women with Gestational Diabetes
Authors: Atere Adedeji David , Chukwuemeka Cinderella Ebele , Popoola Olayiwola Akanji , Olawoye Temiloluwa Deborah 
Published: December 2022

Background:
Gestational diabetes mellitus(GDM) is carbohydrate intolerance that causes hyperglycemia in pregnancy. It increases maternal and perinatal mortality. This study aims to determine the relationship between gestational diabetes and plasma iron and methemoglobin levels.

Methods:
The study included 40 GDM patients, 30 nongestational diabetes pregnant women (NGPW) attending the antenatal clinic of Federal Medical Centre, Owo, and 30 women with neither diabetes nor pregnancy (NDNP). Ten milliliters of venous blood was collected from each individual and dispensed into an appropriate bottle. Fasting blood sugar (FBS), serum level of iron (Fe2+), methemoglobin (MetHb) concentration, and packed cell volume (PCV) were determined using standard laboratory techniques. The data were properly analyzed statistically, and P < 0.05 was considered statistically significant.

Results:
The mean value of MetHb and Fe2+ was significantly higher among GDM and NGPW when compared with NDNP (P < 0.05) while the mean value of PCV was considerably lower (P < 0.05). Furthermore, there was a significant positive correlation between FBS and PCV in GDM, while FBS had a negative correlation with only Fe2+ in GDM.

Conclusion:
It was concluded that elevated serum iron levels and MetHb were found to be associated with the development of GDM in this study, and could thus be used as biomarkers for assessment.
Plasmid-mediated AmpC β-Lactamase Gene Analysis in Klebsiella Pneumoniae Clinical Isolates
Authors: Jomehzadeh Nabi , Ahmadi Khadijeh , Shaabaninejad Hasti , Eslami Gholamali 
Published: December 2022

Background:
In Gram-negative bacteria, including Klebsiella
pneumoniae, the production of AmpC beta-lactamase enzymes is one of the main resistance mechanisms for beta-lactam antibiotics. This study aimed to investigate the phenotypic and molecular characteristics of AmpC beta-lactamases in K.
pneumoniae clinical isolates in Southwest Iran.

Methods:
This study was conducted on 55 K.
pneumoniae strains collected from various clinical samples. Identification of isolates was done using routine bacteriological and biochemical tests. After performing the antibiotic sensitivity test, the cefoxitin-resistant strains were analyzed using the phenotypic test in terms of the production of AmpC beta-lactamase enzymes. Finally, the frequency of plasmid-mediated AmpC genes was determined using a polymerase chain reaction test.

Results:
Out of the 55 isolates, 63.6% (n = 35) were obtained from urine, 9.1% (n = 5) from blood, 12.7% (n = 7) from wounds, and 14.6% (n = 8) from sputum. The highest resistance rate was observed against amoxicillin (98.2%), followed by cefotaxime (78.2%) and ceftriaxone (72.7%). According to the phenotypic tests, the prevalence of AmpC producers was 25.4%. Of all isolates, 36.3% (20/55) harbored different AmpC-associated genes, and bla
MOX, bla
CIT, bla
EBC, and bla
DHA genes were detected in 1, 2, 8, and 13 strains, respectively. None of the isolates harbored bla
ACC and bla
FOX genes.

Conclusion:
It is important to revise the prescription policy of effective antibiotics in this region, since a significant prevalence of AmpC beta-lactamase-producing isolates has made antibiotic resistance a serious concern.
The Prediction of Lung Cancer Prognosis with Blood Lipid Levels and Ratios at the Time of Diagnosis
Authors: Arslan Ferhat , Yalçin Selim , Karahan Irfan 
Published: December 2022

Background:Emerging evidence has linked lipid metabolism disorder with lung diseases, but the relationship between blood lipid profile and lung cancer risk is controversial and inconclusive. It was aimed to investigate the relationship of lipid levels and ratios at the time of diagnosis to the prognosis prediction of lung cancer.Methods:Sociodemographic and disease-related clinical characteristics of 92 patients diagnosed with lung cancer were reviewed retrospectively. Patients with available lipid parameters at the time of diagnosis were evaluated. Hemogram parameters of the patients included in the study, creatinine and estimated glomerular filtration rate, alanine aminotransferase level, albumin level, C-reactive protein level, as well as total cholesterol (TC)/high-density cholesterol (HDL) ratio, non-HDL/HDL ratio, low-density lipoprotein/HDL ratio, and triglyceride/HDL ratios were examined.Results:The mean age at presentation was 64.2 ± 9.1 years. The distribution of lung cancers is 6 (6.5%) for small cell lung cancer (SCLC) and 86 (93.5%) for non-SCLC. The median follow-up period of the patients is 12 months. During the follow-up, 63 (68.5%) of the patients died. In the univariate analysis, increased non-HDL/HDL ratio was related to mortality. In multivariate analysis, disease stage, albumin level, and TC level were found to be variables affecting the mortality.Conclusion:TC levels at the time of diagnosis can be a guide in determining the prognosis. More experimental studies are needed to elucidate the relationship between the lipid metabolism and lung cancer etiology and to determine the role of lipid levels and ratios in prognosis prediction.
Intensive integrated yoga therapy on lipid profile, body composition, and insulin resistance among Type 2 diabetes mellitus
Authors: Bilagi Ashween , Kurian Jintu , Bilagi Shilpa 
Published: December 2022

Background:
Insulin resistance (IR) is a leading cause of the onset of Type 2 diabetes mellitus (T2DM) among overweight and obese individuals irrespective of their age. This study aimed at assessing the impact of 2 weeks of intensive integrated yoga therapy (IIYT) among overweight individuals diagnosed with T2DM identified with higher IR.

Methodology:
The current single-group longitudinal pre–post study enrolled adults (n = 30) from a residential health-care center, Bengaluru (India), who were subjected to IIYT, comprising practices at physical, emotional, and intellectual levels incorporating āsana (postures), prānāyāma (breathing exercise), kriyā (internal cleansing technique), meditation, notional correction, counseling, yogic diet, and devotional sessions. Pre- and postoutcome measures were homeostatic model assessment for IR (HOMA-IR), fasting serum insulin, lipid profile, body composition, and anthropometric measurements.

Results:
A significant reduction in HOMA-IR (35.69%, p < 0.001), fasting insulin (28%, p < 0.001), fasting glucose (12.3%, p = 0.039), triglycerides (15.43%, p = 0.003), very low-density lipoprotein (15.5%, p = 0.003), body mass index (2.4%, p < 0.001), weight (2.3%, p < 0.001), hip circumference (1.01%, p < 0.001), waist circumference (1.4%, p < 0.001), and body fat percentage (1.8%, p = 0.039) and a significant increase in lean mass percentage (0.95%, p = 0.045) and water percentage (0.99%, p = 0.04) were observed among the subjects.

Conclusion:
Regular practice of IIYT regulates lipid and anthropometric measures and increases lean body mass, thereby managing IR, among overweight Type 2 diabetes. However, future works might confirm the findings of the present study.
Effect of 6 month-yoga training on mental health of Indian jail inmates
Authors: Arya Sadhana , Pal Rameswar , Jain Khushbu , Badoni Sachendra , Kaushik Jitender , Gond Pooja Kumari , Basavaraddi Ishwar V. 
Published: December 2022

Introduction:
Prisoners are vulnerable to mental health-related problems. The present study was conducted to determine the effect of 6 months Yoga practice on the mental health of jail inmates. The study's main objective was to assess the impact of 6 months of Yoga practice on the mental health of Jail inmates.

Materials and Methods:
A total of 37 Tihar Jail inmates (27 males and 10 females) participated in the study. With the help of questionnaires, anxiety, depression, stress, aggression, physical health, psychological health, and general well-being of the jail inmates were assessed. The study employed a Single Group Repeated Measures design. Pre and posttest methods were adopted in the study.

Results:
Significant reduction in stress and aggression and improvement in physical health, psychological health, and general well-being were found after 6 months Yoga-training; however, there was no significant reduction in anxiety and depression in the combined group. In male inmates, anxiety, depression, stress, and aggression were reduced significantly, and their physical health, psychological health, and general well-being significantly improved after 6 months of Yoga training. In female inmates, aggression got reduced after 6 months of regular Yoga practice; but no significant changes were found in other parameters.

Conclusion:
Regular Yoga practice for 6 months significantly improved the mental health of Tihar Jail inmates, especially male inmates. However, there is a need to conduct more studies to confirm the results.
ERGONOMIC ENVIRONMENT PREVENTING ACCIDENTS FROM NATURAL DISASTERS
Authors: Gempur Santoso  
Published: December 2022

Life and human life are in the natural environment. In nature can not be separated from natural disasters. Risks so as not to be overwritten by natural disasters require preventive measures. This paper discusses about the ergonomic environment as a measure to prevent accidents due to living and doing activities in nature on sloped land. This scientific writing design uses descriptive by presenting several opinions or research results. Methods of data collection using literature study. The inference method is done using deductive. Conclusion: a). The slope of the slope has a very significant effect on soil damage, including causing landslides, so that a slope of 0 -7 degrees is flat and very sloping land, the best for settlements and a slope of 7 - 15 degrees is sloping land, not dangerous for humans to build settlements, only requires soil hardening/accompaniment treatment. b). Ergonomic natural environment is a deep ecosystem shaping the terrestrial and aquatic environments to create within human and natural boundaries so that the natural work environment makes human activities safe, secure, comfortable, and healthy in life. Suggestion: It is hoped that the community will pay attention to ergonomic conditions, harden or provide hard assistance on sloped land, and avoid living on steep and steep slopes, so as to avoid the risk of landslides
Development and Technology Application of Smart hospitals in China
Authors: Tan Jielong 
Published: December 2022

The construction of smart hospitals will help improve the medical experience of patients and the efficiency of doctors. Smart hospitals can also realize medical smart auxiliary diagnosis decisions and effectively promote the improvement of national health standards and the development of the medical field. China is the world's most populous country, and its smart medicine is developing rapidly. The scale of the trillion medical market has a huge economic and market prospect. It is of great significance to adequately understand the construction and development of smart hospitals in China. This paper focuses on the construction of smart hospitals in China, the definition, connotation, and significance of smart hospitals were elaborated, and the problems in the construction of smart hospitals in China. Reviewed the development stages and research status of smart hospitals construction, analysed problems, technologies, and challenges that exist in the construction of smart hospitals. Finally, the three application scenarios of "Smart medical care", "Smart Service" and "Smart Management" were analysed to provide reference for the construction of smart hospitals based on huge data, artificial intelligence, Internet of Things, and 5G technology.
خواب ، تعبیر اور علمائے برصغیر کی مکتوبات کے ذریعے ان کی راہنمائی
Authors: Alam Nadia 
Published: December 2022

Sleep is an essential part of human life and in one way or another, the dreams that occur in it also have a significant place in human lives. Dreams, especially the good dreams, are also mentioned in Qur'an and Hadith. It is proven that the Holy Prophet Muhammad ﷺ himself used to interpret them and his ﷺ holy companions and followers followed his ﷺ lead. In the context of subcontinent, the written literature of the region contains a considerable material (especially from the eleventh and twelfth centuries AH) on Muslim scholars’ explanation and interpretation of dreams. This article investigates the ways dreams were interpreted in the epistles of the religious scholars of that time. How did those scholars inform the addressees of their spiritual states and how did they guide them well through the written interpretation of the addressees’ dreams.
Keywords: Sleep, Dreams, Muslim Scholars, Subcontinent, Epistles
Impact of the Enlightenment Spirit on Buddhism
Authors: Qayyum Hafiz Muhammad Abdul 
Published: December 2022

The maximum melodramatic fresh expansions in the Buddhism have been an emerging prevalent actions which risen since the Second World War. In the previous, Buddhist monastics provided educational and ethical leadership to society and the state, but today’s secular organizations have taken over these outdated teaching and wellbeing characters. In a worldwide culture with the Enlightenment spirit, new movements are emerging in Buddhism.
New Japanese Buddhist movements such as SōkaGakkai[1] are well known, and several groups have arisen in other Buddhist cultures, such as FoKuang Shan (FoGuangshan) (FKS) in Taiwan. According to religious scholar, Buddhism was founded in 1967 by a heavenly monk named as Shih Hsing-yun (Shi Xingyun). The initial Buddhism preached for working for the welfare of mankind instead of preaching of ‘rebirth’ after the death of the man.

[1]SōkaGakkai (Value Creation Society).
Edukasi Penilaian Kelayakan Keuangan Proyek Pengelolaan Sampah Untuk Non-Governmental Organizations (NGOs) Lingkungan Di Indonesia
Authors: Surachman Eko Nur , Handayani Dian 
Published: December 2022

Pengabdian kepada masyarakat (PKM) ini bertujuan untuk memberikan edukasi atas pengukuran kelayakan keuangan proyek pengelolaan sampah di Indonesia. Kegiatan ini diberikan oleh Tim PKM Politeknik Keuangan Negara STAN kepada Lembaga Swadaya Masyarakat (LSM) Lingkungan di Indonesia yang diselenggarakan Tahun 2021. Metode pelaksanaan kegiatan pengabdian kepada masyarakat terdiri dari tahap perencanaan, tahap, tahap pelaksanaan dan tahap evaluasi. Tahap perencanaan dilakukan dengan permintaan narasumber oleh perwakilan mitra, diskusi antara dengan Tim dan Mitra terkait dengan konsep acara dan materi yang akan disampaikan, dan penyusunan materi oleh Tim. Tahap kedua dilakukan dengan penyampaian materi oleh narasumber kepada peserta dan diskusi atas materi yang sudah disampaikan oleh narasumber kepada peserta. Tahap ketiga adalah evaluasi atas tingkat pemahaman peserta atas materi yang telah disampaikan. Kegiatan PKM ini memberikan manfaat bagi peserta yang sebagian besar berasal dari LSM Lingkungan di Indonesia, dalam memahami kelayakan keuangan proyek pengelolaan sampah di Indonesia. Selain itu, peserta diharapkan dapat mengidentifikasi faktor-faktor yang berpengaruh kepada kelayakan keuangan proyek pengelolaan sampah di Indonesia.
EFFECT OF SOUS VIDE HEAT TREATMENT ON PHTHALIC ACID ESTERS CONTENT IN MEAT
Authors: Cubon Juraj , Jarošová Alžbeta , Haščík Peter , Herc Peter , Hlebová Miroslava , Hleba Lukáš , Bučko Ondřej , Kováčik Anton , Capcarová Marcela 
Published: December 2022

The chemical composition and content of DBP (di-n-butyl phthalate) and DEHP (di-2-ethylhexyl phthalate) in pork shoulder before and after heat treatment in the package by the sous vide method was analyzed. The meat was analyzed raw and after heat treatment at 50 °C and 60 °C. The heat treatment time in the sous vide water bath was 4 hours, 4 hours + 1 hour after 24 hours, 8 hours and 8 hours and 1 hour after 24 hours. The fat content in meat treated at 50 °C was 6.04 in raw meat and after heat treatment after 4 hours. 7.51 and after 8 h. 6.81 g.100g-1, in the shoulder after heat treatment at 60 °C was after 4 hours 6.24 and after 8 h. 6.76 g.100g-1. The content of fatty acids during the sous vide treatment did not significantly change with exception of vaccenic acid, the content of which was statistically significantly reduced at temperatures of 50 °C also at 60 °C. The DBP content in raw shoulder at 50 °C during sous vide heat treatment it increased to 1.91 μg.g-1. The DEHP content during the heat treatment it increased to 23.95 μg.g–1 in the treatment of 4+1 hours. The DBP content in raw shoulder after heat treatment at 60 °C increased to 1.84 μg.g–1 during treatment for 4+1 hours. The DEHP content decreased to 8.72 in the treatment of 4+1 hours and to 4.021 μg.g–1. Based on our results, we can conclude that at both monitored temperatures of sous vide method, the DBP content increased and the DEHP content decreased. The DBP content in raw shoulder at 50°C heat treatment increased to 1.91 μg.g-1 at 4+1 hour heat treatment and to 3.02 at 8+1 hour. The DEHP content increased to 23.95 μg.g-1 in the treatment of 4+1 hours. The content of DBP and DEHP in the packaging material before use was 29.08 μg.g-1, it gradually decreased with the length of the heat treatment, to 15.09 μg.g-1 in the treatment of 8+1 hours. The DEHP content in the unused package decreased to1.27 μg.g-1 at heat treatment of 8+1 hours. At the heat treatment at of 60°C in the packaging material gradually decreased to 3.18 μg.g-1. The DEHP content decreased to 2.54 μg.g-1.
Cuidando de quem cuida
Authors: Leiria Carine Mokfa , Ferronatto Jéssica , Weiler Silvana Luzia , Mengue Bárbara Vier 
Published: December 2022

A sociedade contemporânea é marcada pela contínua e rápida transformação dos cenários, exigindo adaptação aos desafios e reconfiguração das prioridades. Esse ritmo alucinante gera a sensação de o tempo ser insuficiente para realizar o necessário e o desejado, inferindo diretamente na dignidade e estima pessoal, pois ativa o julgamento externo sobre os elementos de produtividade. [...]
Construção e entrega de pareceres descritivos
Authors: Grahl Leila Fernandes , Mengue Bárbara Vier 
Published: December 2022

A relação entre os pais e a escola é permeada por muitos fatores que se evidenciam através da solidez dos documentos pedagógicos, uma vez que esses devem estar fundamentados em aspectos que sejam coerentes com a prática pedagógica e seus resultados. Ao observar essa prática em nossa instituição, questionamos quais pontos necessitam de análise e reformulação. Para tanto, aprimorar o processo de construção e entrega, otimizando as informações na construção e facilitando a comunicação de forma eficaz para as famílias, é o objetivo dos questionamentos e da reflexão abordados neste estudo. [...]
GA: espaço de (re) significar e acolher
Authors: Mahle Angélica Heinen , Emmel Sinara da Silva 
Published: December 2022

O presente resumo perpassa pelos estudos desenvolvidos a partir da Trilha 2, intitulada “Educação Inclusiva e escola acolhedora”, do Programa de Formação Continuada Trilhas de Aprendizagem oferecido pela Rede Sinodal de Educação em 2022. A pesquisa foi orientada pela professora Ma. Sinara da Silva Emmel. Ao nos constituirmos como GA, percebemo-nos como um grande ecossistema que educa na diversidade. E educar na diversidade requer um fazer pedagógico que valorize as diferenças da sala de aula, ressignificando os desafios existentes. [...]
Inclusão - psicologia e psicopedagogia
Authors: Oliveira Cíntia Miranda Machado de , Neumann Patrícia Ana , Emmel Sinara da Silva 
Published: December 2022

Felipe é um menino que estuda na IENH desde o ano de 2015, ingressou com 5 anos de idade. Tem uma história de vida cheia de segredos familiares, e o que se sabe é que foi adotado por uma família que não desejava a adoção, mas por circunstâncias da vida acolheu-o como filho. Já mudou de sobrenome e não tem uma história clara sobre seus antepassados. Na caminhada escolar, está atualmente no sétimo ano do Ensino Fundamental e ingressou na escola na Educação Infantil. Acompanhado por profissionais, tem atendimentos com psicóloga, psiquiatra e psicopedagoga. Na escola, além de ser avaliado como aluno de inclusão, faz atendimentos na sala de recursos multifuncionais. [...]

[1] Nome fictício para proteção de dados
Analisis Pengaruh Faktor-Faktor Pendukung Pembelajaran Terhadap Hasil Belajar Sepak Sila Cabang Olahraga Takraw
Authors: Sulistyo Bitdah , Sceisarriya Vega Mareta 
Published: December 2022

Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh faktor-faktor pendukung pembelajaran terhadap hasil belajar sepak sila dalam pembelajaran sepak takraw serta untuk mengetahui hasil analisis faktor-faktor pendukung pembelajaran terhadap hasil belajar sepak sila.Rumusan masalah dalam penelitian ini adalah bagaimana analisis pengaruh faktor-faktor pendukung pembelajaran terhadap hasil belajar sepak sila dalam pembelajaran sepak takraw.Dalam penelitian ini, peneliti menggunakan metode dokumentasi. Hasil analisis data, paparan data, dan tamuan data menunjukkan bahwa terdapat pengaruh faktor-faktor pendukung pmbelajaran terhadap hasil belajar sepak sila mencakup permasalahan, persamaan, perbedaan, pandangan peneliti, dan hasil penelitian dalam beberapa artikel yang berjudul (1) pengaruh modifikasi bola takraw terhadap hasil belajar sepak sila, (2) hubungan koordinasi mata kaki terhadap keterampilan sepak sila permainan sepak takraw, (3) hubungan keseimbangan dan kelincahan terhadap keterampilan sepak sila, (4) pembelajaran kontrol berpasangan terhadap hasil sepak sila, (5) hubungan keseimbangan terhadap kterampilan sepak sila. Berdasarkan penelitian analisis pengaruh faktor-faktor pendukung pembelajaran terhadap hasil belajar sepak takraw dapat disimpulkan adanya pengaruh terhadap hasil belajar sepak takraw berdasarkan paparan data beberapa artikel yang sudah direview.