bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estimation of Serum CD200 and CD200R1 Levels in a Sample of Iraqi Women with Breast Cancer: Their Role as Diagnostic and Prognostic Markers
Authors: Ismail Adnan M. , Saleh Eman S 
Published: January 2022

Breast cancer is a disease in which cells in the breast grow out of control. CD200 is a cell surface glycoprotein expressed on many cells, it belongs to the immunoglobulin family (Ig) and have a great role in the regulation of inflammation in autoimmunity. CD200 is the ligand for CD200R1 receptor. To determine if serum level of CD200 and its receptor CD200R1 can be used as a diagnostic and prognostic marker in patients with breast cancer.This case control study was carried out at Oncology Teaching Hospital – Medical city in Baghdad. Six groups were enrolled, four groups were confirmed with breast cancer stage (I, II, III and IV), fifth group (benign) and sixth group was control (healthy individual). Serum is divided to measure CD200 and CD200R1 by utilizing quantitative sandwich enzyme-linked immunosorbent assay (ELISA) Kits.
Serum level of CD200 was significantly different (P=0.000088) between breast cancer patients and control only, serum level of CD200 increases with disease stage and there is a significant positive correlation. Serum level of CD200R1 was different with stage, although the differences were not significant but the level of CD200R1 is lower in stage 4 patients than other stages.
Serum CD200 level can be used as a diagnostic marker for breast cancer. Serum level of CD200R1 can be used as a prognostic marker
Participation and Attitudes: An Exploratory Look into the Current Ontario French as a Second Language Program at the Secondary School Level
Authors: Flaubert Takam Alain , Gillis Steven A. 
Published: January 2022

Cet article présente une étude sur les perceptions et les attitudes des intervenants clés tels que les élèves, les parents et les enseignants dans le programme de FLS de l’Ontario, et les impacts potentiels que ces attitudes pourraient avoir sur la participation future à l’apprentissage du FLS dans les écoles secondaires de la province. Il sont également examinées certaines pratiques d’enseignement et d’apprentissage dominantes en relation avec le développement des programmes de FLS en Ontario. Plus précisément, l’objectif de l’article est de répondre aux trois questions suivantes : Comment le programme actuel de FLS de l’Ontario est-il perçu par certains intervenants clés ? Qu’est-ce qui peut influencer ces perceptions ? Quelles sont certaines des implications possibles pour l’avenir du FLS en Ontario, surtout en ce qui concerne la participation ? Les données analysées dans cet article proviennent des questionnaires qu’ont remplis les élèves, les parents et les enseignants de FLS. Ce travail de terrain a été effectué dans six écoles secondaires de trois conseils scolaires de l’Ontario, dont deux étaient catholiques et l’autre public.
A discursivização das emoções em tempos de COVID-19: um olhar do ponto de vista filopsicológico
Authors: De Oliveira Antonio Flávio Ferreira , De Souza Lisandra Ferreira , De Moura Giovanna Barroca 
Published: January 2022

Neste trabalho, foi discutida a discursivização das emoções em imagens da internet, em tempos de Covid-19. Para tanto, objetivou-se investigar, nessas imagens, os afetos resultantes dos modos de enfrentamento da pandemia. Teoricamente, foram abordados conceitos da filosofia do Círculo de Bakhtin, da retórica de Aristóteles e do campo da psicologia. Metodologicamente, a pesquisa é qualitativa de cunho interpretativista e o corpus consta do conjunto de seis (06) imagens extraídas da internet. Como resultado, constataram-se, das imagens, reflexos de respostas a estímulos significativos para criar na população a repetição de um imaginário coletivo que constituiu possíveis representações do lado mais sombrio da Covid-19.
Palavras-chave: Filosofias de Bakhtin e de Aristóteles. Discursivização. Emoção. Covid-19.
Pseudoexfoliation Glaucoma and its Systemic Association: A Clinical Study
Authors: Ramamurthy Lakshmi B , Chandrashekarabhatta Sahana Nemmar , R Sudheendra B 
Published: January 2022

Pseudoexfoliation [PXF] being a age related elastotic process is a well known entity among all ophthalmologists. PXF is most common form of secondary glaucoma.
Objective: To study the clinical presentations and response to treatment of PXF glaucoma and also to throw light on its systemic associations.
Methods: A total of 70 eyes of PXF glaucoma was considered for the study in duration of 6 months from june to November 2021 at a tertiary care center. All patients underwent detailed ophthalmic evaluation along with gonioscopy, optic disc assessment, visual fields and intraocular pressure. Based on all these , patients were graded as mild, moderate and advanced glaucoma and treated accordingly either with medical or surgical line of management. Patients were followed up for a duration of 6 months. ECG, echocardiography and dermatological evaluation of all the patients were done.
Results: Mean age of 70 patients was 52.2 years and there was male preponderance .Powdery greyish white pseudoexfoliative material on pupillary margin was seen in 41 eyes[58.5%] and on anterior capsule was seen in 19 eyes[27.1%]. IOP in these 70 patients ranged between 14 to 40mmHg. Gonioscopy showed exfoliative material deposition in 14 eyes[20%] and increased pigmentation of trabecular meshwork in 44 eyes[62.85%]. Also, it revealed narrow angle( grade 1&2) in 6 eyes and open angle (grade 3&4) in rest .Visual filed changes were present in 57 of 70 eyes with PXF glaucoma. Optic disc changes in PXF glaucoma also showed variations with 17 eyes having CD ratio of<0.5,while 38 eyes had a cupping between 0.6-0.8. Eleven eyes showed advanced cupping of >0.8 while 4 eyes had glaucomatous optic atrophy.60 eyes were treated with medical line while 10 eyes were managed surgically. 4 patients had dermal nodules and diastolic dysfunction was noted in 31 patients.
Conclusion: PXF confers a significantly higher risk of developing glaucoma in comparison with the general population and needs close monitering. PXF glaucoma and its systemic associations also has to be considered
Keywords: PXF, pseudoexfoliative, ECG
ANALISIS KEBUTUHAN LAYANAN DIGITAL E-GOVERNMENT DI PEMERINTAHAN KABUPATEN MUSI BANYUASIN
Authors: S Lily Pebriana. , Antoni Darius , Akbar Muhamad , Cholil Widya 
Published: January 2022

ABSTRAK

Kabupaten Musi Banyuasin adalah salah satu kabupaten di Sumatera Selatan yang telah menyediakan atau menerapkan e-government untuk melayani semua lapisan masyarakat. Contohnya adalah penerapan Muba Smart Regency diantaranya program Pemerintah Kabupaten Musi Banyuasin (Muba) melalui Dinas Komunikasi dan Informatika Musi Banyuasin dalam mencetuskan program Muba Siaga 112. Walaupun, Kabupaten Musi Banyusin telah menerapkan e-Government untuk melayani setiap lapisan masayarakat, tetapi masayarakat desa belum secara merata untuk dapat menikmati layanan tersebut. Hal ini dikarenakan kondisi yang ada berikut ini : Infrastruktur di Kabupaten Musi Banyuasin tidak merata dan keadaan geografis Kabupaten Musi Banyuasin masih banyak persawahan dan rawa-rawa. Kabupaten Muba juga melalui tangan dingin Bupati Dodi Reza Alex Noerdin juga melakukan pembangunan Muba Command Centre dan pemasangan CCTV dibeberapa sudut kota Sekayu yang terkoneksi dengan Polres Muba dan Pemkab Muba sebagai tanda dimulainya Muba Smart Regency. Dalam waktu yang tidak terlalu lama Kabupaten Muba masuk dalam gerakan 100 Smart City Indonesia. Sehingga ke depan Bupati Muba tidak hanya fokus pada pembangunan infrastruktur digital saja, melainkan pembangunan komunitas digital juga dilakukan.
Predictors of Post-Operative Acute Kidney Injury in relation with N-Terminal Pro-B-Type Natriuretic Peptide Level among Patients Undergoing Mitral Valve Replacement
Authors: Hossain Md Tanvir , Hoque Asraful , Rubayath Tasmin , Rahman Romena , Saem Khan Abu Shadat Mohammad , Mozumder Md Noor-E-Elahi , Hossain Md Monzur , Ahmed Imran , Ahsan Chowdhury Muhammad Asif , Salam Wahida 
Published: January 2022

Background: The N-terminal Pro-B-type natriuretic peptide (NT-proBNP) level can be utilized as post-operative prediction models suring cardiac surgery.
Objective: The objective was to find out the predictors of post-operative acute kidney injury in relation with N-Terminal Pro-B-Type natriuretic peptide level among mitral valve replacement patients.
Methodology: This cross-sectional study was conducted in the Department of Cardiac Surgery at National Institute of Cardiovascular Diseases, Dhaka, Bangladesh from January 2018 to December 2019. Patients with the age of more than or equal to 18 years with both sexes who were underwent mitral valve replacement were selected as study population. Patients were divided into two groups based on pre-operative NT-proBNP level. Post-operatively patients were observed on the basis of post-operative serum creatinine.
Results: A total number of 100 patients were recruited for this study of which 50 cases were in group A and the rest of 50 cases were in the group B. Elevated NT-proBNP was the most powerful and independent pre-operative variable in predicting post-operative AKI development (OR 0.999, 95% CI 0.998-1.00) Conclusion: In conclusion elevated NT-proBNP is the most powerful and independent pre-operative variable in predicting post-operative acute kidney injury.
Journal of Current and Advance Medical Research, July 2021;8(2):85-89
Comparison of Ultrasonographic Evaluation of Gallbladder Volume in Type II Diabetic Patients with Non-diabetic Healthy Subjects
Authors: Tahnia Nushrat Jahan , Hossain Mohammad Shakhawat , Khan Saneat Jahan , Hossain Md Shahadat 
Published: January 2022

Background: Measurement of increased gallbladder volume is necessary for the detection of pathology of gallbladder.
Objective: The purpose of the present study was to find out the difference between ultrasonographically measured gall bladder volume in fasting and post prandial states of type II diabetic patients and non-diabetic control subjects.
Methodology: This cross-sectional study, carried out department of Radiology and Imaging at Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) Hospital, Dhaka, Bangladesh from June 2013 to July 2014. The type II diabetic patients were selected as group A and the healthy individual with age and sex matched were selected as group B. An ultrasonographic evaluation of fasting gallbladder volume and 2 hours after meal was done in all the subjects using a 3.5 MHz transducer. Information was recorded in preformed data collection sheet.
Results: There was statistically significant (p<0.001) difference of mean fasting gall bladder volume between diabetic and non-diabetic subjects. The mean postprandial gall bladder volume of type II diabetic patients was significantly higher than that of the non-diabetic controls. By using Karl-Pearson coefficients of correlation it was found that gallbladder enlargement in type II diabetics, was significantly correlated with body mass index (p= 0.05) and systolic blood pressure (p= 0.05).
Conclusions: Cholecystomegaly is found in type II diabetics in the present study to a significant degree which is also significantly correlated with body mass index and systolic blood pressure.
Journal of Current and Advance Medical Research, July 2021;8(2):114-118
ANALISIS MODEL DESAIN BANGUNAN BANK SAMPAH DI KELURAHAN TARAU KECAMATAN KOTA TERNATE UTARA
Authors: Basri Ardi , Muhammad Asri A. , Purnomo Hery 
Published: January 2022

Abstrak Sampah merupakan permasalahan laten yang terjadi di Indonesia. permasalahan sampah menjadi tanggung jawab bersama antara pemerintah dan masyarakat. Melalui Peraturan Menteri Negara Lingkungan Hidup Republik Indonesia Nomor 13 Tahun 2012 Tentang Pedoman Pelaksanaan Reduce, Reuse, dan Recycle Melalui Bank Sampah, menjadi salah satu alternatif penanggulangan masalah sampah. Bank Sampah dapat dioptimalkan di tingkat kelurahan sampai perkotaan sesuai dengan standard yang telah di tetapkan dalam Permen LH no. 13 tahun 2012. Kelurahan Tarau di Kecamatan Ternate Utara, memiliki satu buah Bank Sampah yang pengelolaannya masih bersifat individu dan belum memenuhi standard dari peraturan pemerintah. Melalui penelitian ini, diharapkan bangunan Bank Sampah yang ada di Kelurahan Tarau dapat dioptimalkan secara pengelolaan maupun standard bangunan dan dapat menjadi salah satu alternatif solusi permasalahan sampah di kota Ternate. Metode penelitian yang digunakan adalah penelitian deskriptif kualitatif dengan pendekatan studi kasus untuk dapat menjawab tujuan dari penelitian ini dengan tahapan survey lapangan, analisis data, konsep rancangan dan tahap desain. Sedangkan tujuan dari penelitian ini adalah mendesian bangunan Bank Sampah sesuai standard Peraturan Menteri Negara Lingkungan Hidup Republik Indonesia Nomor 13 Tahun 2012.Kata kunci: Bank Sampah, Kelurahan Tarau, Standard, Ternate
Analisis Dampak Peningkatan Kualitas Jalan Kabupaten Terhadap Peningkatan Kesejahteraan Masyarakat di Kecamatan Mataoleo
Authors: Silfiani Silfiani , Firman Akhmad , Azikin Thahir 
Published: January 2022

Infrastruktur jaringan jalan, memiliki keterkaitan dengan pertumbuhan ekonomi suatu wilayah. Tujuan penelitian ini yaitu menganalisis dampak peningkatan kualitas jalan kabupaten terhadap perubahan pendapatan, menganalisis dampak peningkatan kualitas jalan kabupaten terhadap peningkatan aksesibilitas masyarakat, dan menganalisis dampak peningkatan kualitas jalan Kabupaten terhadap peningkatan nilai jual lahan di Kecamatan Mataoleo. Metode yang digunakan yaitu uji wilcoxon, indeks aksesibilitas dan uji chi square. Hasil dari penelitian ini yaitu adanya peningkatan pendapatan masyarakat dari tahun 2014 hingga tahun 2018 terhadap peningkatan kualitas jalan. Nilai indeks aksesibilitas dari tahun 2014 hingga tahun 2018 tidak terdapat perubahan namun terjadi peningkatan waktu tempuh perjalanan. Ini terjadi karena tidak ada penambahan pembukaan jalan baru. Nilai jual lahan terjadi peningkatan pada tahun 2014 ke tahun 2018. Kata Kunci : Kesejahteraan, Kualitas jalan, Peningaktan
PEMETAAN 3D RUANG TERBUKA HIJAU KOTA KENDARI 3D MAPPING OF KENDARI CITY GREEN OPEN SPACE
Authors: Sufrianto Sufrianto , Danggi Erni , Hawa Sitti 
Published: January 2022

Tujuan dari penelitian ini adalah untuk mengetahui sebaran Ruang Terbuka Hijau (RTH) dan Luasan RTH dengan menggunakan Aplikasi Sistem Informasi Geografi (SIG), Aplikasi Tiga Dimensi dan Aplikasi Office.Teknik analisis yang digunakan dalam penelitian ini adalah analisa spasial dengan cara Overlay (tumpang tindih) menggunakan Citra Spot 6&7 tahun 2018 yang selanjutnya di analisis menggunakan aplikasi Sistem Informasi Geografis (SIG) di padukan dengan aplikasi tiga dimensi (3D), Peta hasil overlay citra Spot 6&7, data ruang terbuka hijau dan DEM disatukan dalam aplikasi Tiga Dimensi sehingga tampilan peta digital berbentuk gambar peta 3D,Animasi 3D dan Simulasi Banjir.Tingkat Kesiapan Teknologi (TKT) dalam penelitian ini adalah pembuata peta Ruang Rerbuka Hijau (RTH) dengan menggunakan aplikasi pemetaan yang bisa menghasilakan peta sebaran RTH, Peta 3d sebaran RTH dan Simulasi Banjir pada DAS WangguHasil dari penelitian ini adalah Peta Sebaran Ruang Terbuka Hijau (RTH) dan luasan RTH Kota Kendari, dari hasil analisis diperoleh luasan sebesar 8.29,31 Ha, atau 31,02 % dari luas wilayah Kota Kendari 26.737 Ha, hal ini sesuai dengan Undang-Undang Nomor 26 Tahun 2007 tentang Penataan Ruang dimana ditetapkan paling sedikit 30 %Kata Kunci: Peta 3D, Ruang Terbuka Hijau
Analisis Prioritas Konsep Dan Strategi Penanganan Kawasan Permukiman Kumuh Di Kecamatan Nambo
Authors: Astija Sitti , Kadir Ishak , Yusuf Dewi Nurhayati 
Published: January 2022

Kawasan permukiman kumuh di Kecamatan Nambo terbagi atas Kluster Pudai – Nambo (Kelurahan Bungkutoko, Petoaha, Nambo) dan Kluster Tondonggeu – Sambuli. Tipologi permukiman di Kecamatan Nambo merupakan dataran rendah dan tepi air. Penelitian ini bertujuan untuk menganalisis skala prioritas, menentukan konsep dan strategi penanganan kawasan kumuh di Kecamatan Nambo. Metode yang digunakan dalam penelitian ini yaitu deskriptif kuantitatif dengan menggunakan analisis pembobotan indikator prioritas kawasan kumuh berdasarkan Peraturan Menteri PU No. 2 Tahun 2016. Hasil penelitian menunjukkan bahwa kawasan kumuh di Kecamatan Nambo terbagi atas dua klasifikasi prioritas yaitu kumuh sedang, status lahan tidak legal dan pertimbangan lainnya tinggi dan kumuh sedang, status lahan tidak legal dan pertimbangan lain sedang. Berdasarkan kondisi kekumuhan di Kecamatan Nambo maka konsep/ pola penanganan kawasan permukiman kumuh yaitu permukiman kembali. Rumusan strategi; penyiapan lahan, rehabilitasi/perbaikan bangunan hunian, rehabilitasi/ perbaikan infrastruktur permukiman dan rehabilitasi/ perbaikan proteksi kebakaran. Kata Kunci : Kawasan Kumuh, Konsep, Nambo, Prioritas, Strategi
Pemetaan Sebaran Kecelakaan Kapal Di Perairan Laut Sulawesi Tenggara
Authors: Asep Asep , Ramli Muhammad , Tadjuddah Muslim 
Published: January 2022

Data on ship accidents that have been handled by the Kendari Search and Relief Office (BASARNAS) from January 2015 to December 2019 recorded 198 ship accidents with a total of 4,517 victims, including 4,386 survivors, 103 people died and 29 victims were not found.This study aims, (1) map the distribution of ship accidents, and (2) analyze the potential for ship accident-prone areas. The results showed that the distribution of ship accidents from 2015 - 2019 in the sea waters of Southeast Sulawesi was categorized as clustered. There are two red zones on the shipping lane, namely in Wakatobi Waters and Kendari Waters. Keywords: mapping, ship accidents, watersData kecelakaan kapal yang telah ditangani Kantor Pencarian dan Pertolongan Kendari (BASARNAS) pada bulan Januari 2015 sampai dengan bulan desember 2019 tercatat 198 kecelakaan kapal dengan jumlah korban sebanyak 4.517 orang, diataranya yang selamat sebanyak 4.386 orang, meninggal 103 orang dan tidak ditemukan atau hilang sebanyak 29 orang. Penelitian ini bertujuan, (1) memetakan sebaran kecelakaan kapal, dan (2) menganalisis potensi wilayah rawan kecelakaan kapal. Hasil penelitian menunjukan bahwa sebaran kecelakaan kapal dari tahun 2015 - 2019 di perairan laut Sulawesi Tenggara dengan kategori mengelompok (Clustered). Terdapat dua Zona merah pada jalur pelayaran yaitu di Perairan Wakatobi dan Perairan KendariKata Kunci : pemetaan, kecelakaan kapal, perairan
Biosynthesis of Chiral Amino Alcohols via an Engineered Amine Dehydrogenase in E. coli
Authors: Tong Feifei , Qin Zongmin , Wang Hongyue , Jiang Yingying , Li Junkuan , Ming Hui , Qu Ge , Xiao Yazhong , Sun Zhoutong 
Published: January 2022

Chiral amino alcohols are prevalent synthons in pharmaceuticals and synthetic bioactive compounds. The efficient synthesis of chiral amino alcohols using ammonia as the sole amino donor under mild conditions is highly desired and challenging in organic chemistry and biotechnology. Our previous work explored a panel of engineered amine dehydrogenases (AmDHs) derived from amino acid dehydrogenase (AADH), enabling the one-step synthesis of chiral amino alcohols via the asymmetric reductive amination of α-hydroxy ketones. Although the AmDH-directed asymmetric reduction is in a high stereoselective manner, the activity is yet fully excavated. Herein, an engineered AmDH derived from a leucine dehydrogenase from Sporosarcina psychrophila (SpAmDH) was recruited as the starting enzyme, and the combinatorial active-site saturation test/iterative saturation mutagenesis (CAST/ISM) strategy was applied to improve the activity. After three rounds of mutagenesis in an iterative fashion, the best variant wh84 was obtained and proved to be effective in the asymmetric reductive amination of 1-hydroxy-2-butanone with 4-fold improvements in kcat/Km and total turnover number (TTN) values compared to those of the starting enzyme, while maintaining high enantioselectivity (ee &gt;99%) and thermostability (T5015 &gt;53°C). In preparative-scale reaction, the conversion of 100 and 200 mM 1-hydroxy-2-butanone catalyzed by wh84 was up to 91–99%. Insights into the source of an enhanced activity were gained by the computational analysis. Our work expands the catalytic repertoire and toolbox of AmDHs.
How Do Virtual Visits Compare? Parent Satisfaction With Pediatric Diabetes Telehealth During the COVID-19 Pandemic
Authors: March Christine A. , Muzumdar Radhika , Libman Ingrid 
Published: January 2022

BackgroundIn response to the COVID-19 pandemic, many countries relaxed restrictions on telemedicine, allowing for a robust transition to virtual visits for routine care. In response, centers rapidly instituted and scaled telemedicine for pediatric diabetes care. Despite numerous center reports on their experience, little is known about parent perspectives on the widespread increase of telemedicine for pediatric diabetes appointments.ObjectiveTo assess parent satisfaction with virtual care for pediatric diabetes during the COVID-19 pandemic.MethodsWe conducted an online, cross-sectional survey of parents of youth with diabetes who receive care at a large, academic diabetes center regarding their perspectives on newly introduced virtual appointments. Parents were surveyed at two time points during the pandemic using a validated scale which was adapted for diabetes. We explored demographic and clinical factors which may influence parental satisfaction.ResultsOverall, parents expressed high levels of satisfaction (&gt;90%) with functional aspects of the visit, though only approximately half (56%) felt the visit was as good as an in-person encounter. Nearly three-quarters (74%) would consider using telemedicine again in the future. Prior use of telemedicine significantly influenced parent satisfaction, suggesting that parent preferences may play a role in continued use of telemedicine in the future. There was no difference in responses across the two timepoints, suggesting high satisfaction early in the pandemic which persisted.ConclusionsIf permissive policies for telemedicine continue, diabetes centers could adopt hybrid in-person and virtual care models, while considering various stakeholder perspectives (providers and patients) and equity in access to virtual care.