bluuebunny/crossref_metadata_2025_split huggingface dataset:
UJI VALIDITAS DAN RELIABILITAS KUESIONER PERILAKU PROSOSIAL
Authors: Rosita Esi , Hidayat Wahyu , Yuliani Wiwin 
Published: June 2022

Good prosocial behavior is important for students to support student success in both the social and academic fields. The one of the measuring tools that can be used is a questionnaire. The purpose of this research is to make a questionnaire along with the validity and reliability test of the questionnaire. The research used is a R&D method with 13 respondents of class XI at SMK Aloer Wargakusumah. Based on the results of the research, it is known that the questionnaire test with 50 statement items shows that there are 36 valid statement items with a comparison between rcount> rtable. While the reliability test shows the Cronbach Alpha value> 0.60, then the questionnaire can be said to be reliable or consistent with the moderate category according to Sugiyono's criteria table. Keywords: prosocial behavior, questionnaire, validity and reliability test
Membrane Technology for Water Pollution Control: A Review of Recent Hybrid Mechanism
Authors: Martini Sri 
Published: June 2022

Current development of membrane technology for purifying polluted water and wastewater is discussed in this review in accordance with its hybrid application with other types of water treatment methods such as adsorption, advanced oxidation processes (AOPs), and biological activated sludge. This hybrid implementation aims are to lengthen membrane lifespan and elude severe fouling on the surface and pore of the membrane. Membrane material and fabrication technology were concisely included. Two prominent materials to fabricate membrane namely polymeric and ceramic are reviewed well along with the exploration of biopolymers based-materials such as starch and alginate. Several fabrication methods available to be implemented in research or industrial large scale including interfacial polymerization technique, non-solvent induced phase separation, temperature induced phase separation, electrospinning, and sintering are deliberately discussed. The next section includes fouling analysis involving reliable fouling mechanism namely Hermia’s models to help with the explanation of fouling occurrence during filtration. These models covers four different mechanisms namely complete blocking, standard blocking, intermediate blocking, and cake filtration models. Ultimately, recent research reporting the outcome of the hybridization of membrane and adsorption, biosorption, coagulation-flocculation, AOPs, and biological treatment using microorganism were properly reviewed. Overall, this review considerably promotes the findings of those works which mostly revealed positive outcome of the hybrid membrane system contributing to stronger foundation for future research.
Towards assisted rationality switching in negotiations
Authors: Nieciecka Weronika , Szapiro Tomasz 
Published: June 2022

Abstract
The text attempts to provide a comprehensive outlook on negotiation processes and support procedures, by deriving a mathematical description based on psychological and managerial context. The authors merge psychological and formal descriptions of the principles underlying the perception of rationality in negotiation problems. The framework allows for explaining the violation of perceived rationality as a result of the deprivation of human needs. The argument, supported by pilot experiments, allows for recommending a procedural approach to negotiation, focused on monitoring perceptions of rationality of proposal submission. The paper is concluded with an attempt to foresight further developments of theoretical investigations and expansion of application fields.
Diagnostic Model of Aircraft Turbine Engine Governor Pump
Authors: Ohanian Ihor , Yepifanov Sergiy 
Published: June 2022

Abstract
This paper presents a mathematical model for a hydromechanical fuel governor pump, to be used in parametric diagnostics. The design and operation of the governor are described. The main requirements of the model are formulated, its structure is determined, corresponding to the specifics of the diagnostic task, and assumptions to make the model simpler are presented (single-dimensional flow and absence of heat exchange). The presented model consists of idealized elements with lumped parameters (such as pressure and mass consumption of the working fluid), accounting for the compressibility of the substance and the design arrangement of the governor (presence of mechanical rests, metering orifices of complex shapes, relay switchers, etc.). Equations of elements with lumped parameters, linked by hydraulic channels in one node, are presented. The model – a system of first-order differential-algebraic equations – is solved and the parameters of the governor pump are determined for different steady-state and transient operation modes. We compare our results to the requirements for the corresponding parameters outlined in the Engineering Specifications. The model is matched to the specifications by correcting setting parameters (tightening of elastic springs, areas of throttles, etc.), and a method of initial model linearization is developed. Based on the results, we conclude that our model can be used as a diagnostic algorithm for a governor pump, at the testing and development stages, during manufacturing, repair and maintenance.
Evaluation of additive interaction in concrete
Authors: Endzhievskaya I. G. , Demina A. V. , Endzhievskii A. S. , Dubrovskaya S. D. 
Published: June 2022

In modern construction, mineral additives are considered as important concrete components, which improve many technical parameters. Being an inert additive, finely dispersed limestone behaves as a reactive one in a system with super- and hyper-plasticizers, especially in a hardening cement, with the formation of a gas phase. The outgassing is influenced by the system rheology and can be significantly increased with deceasing viscosity, for example, when working with self-leveling mixtures. In this case, the micro-filling function of dispersed additives may be not sufficiently implemented, and the optimum content has not a positive effect on the structure and properties of concrete. It is therefore advisable to evaluate the compatibility of mineral and chemical additives, which has been little studied to date.
Architecture of media objects in terms of the IT development
Authors: Bochkareva A. R. , Likhachev E. N. 
Published: June 2022

With the creation of the first computer and beginning of digitalization, the emergence of new functional and planning types of media objects have significantly accelerated. Here belong architectural objects and spaces that solve the problems of communication and information exchange processes. Combined IT and new design approaches to media objects appear by the end of the 20th century. Their architecture reflects a rapid change in the society caused by technological progress, economic and political factors.The development trends of media objects late in the 20th century facilitated the development of multifunctional complexes such as media centers, functional and planning types of which are being currently developed. Design and formation of media centers exhibit a changing cultural paradigm, which reflects the technological progress. The article discusses the impact of rapidly developing information technologies on the architecture of media objects. The main results include the diagram of the evolution of architectural types of media objects in the context of IT and the formation of foreign media centers.
Architecture of palaces of culture and club buildings in Siberia (Novosibirsk, Tomsk, Omsk)
Authors: Dukhanina E. S. 
Published: June 2022

The problem of renovation of club buildings in modern Russia dates back to the 1990s. However, significant reforms in the sphere of cultural objects occurred only in 2013. In order to preserve and improve the existing system of club buildings, it is necessary to update knowledge in the field of club building construction in Siberia.The article studies the formation of Siberian club building in the Soviet and modern theory of architecture. The studies of urban planning and regional architecture of Siberian club buildings distinguish their influence on the development and construction of Siberian cities. Other investigations include the architectural style of club buildings. The latter are regarded as Stalinist architectural monuments, constructivism and creative concept ASNOVA-ARU.
SIFAT SIRALAMALARI ÜZERİNDE YENİ BİR KISITLAMA
Authors: BAYIRLI İsa Kerem 
Published: June 2022

Bu yazıda sıfat sıralamaları ile ilgili yeni bir genelleme ortaya atılmakta ve bu genellemenin Son-üstü-Son Kısıtı tarafından açıklanabileği gösterilmektedir.
Yazıda ilk olarak Son-üstü-Son Kısıtı betimlenmekte ve bu kısıtın açıklayıcı gücüne örnekler verilmektedir. Daha sonra sıfatlar ile ilgili bazı gözlemler ışığında sıfatların dizimi ile ilgili iki analiz sunulmaktadır: (a) bitiştirme analizi ve (b) işlevsel baş analizi. Yazının sonraki bölümünde sıfat sıralamaları üzerinde adına Sıfat Sırası Genellemesi denilen bir kısıtlamanın var olduğu savunulmaktadır. Son olarak sıfatların işlevsel baş analizi varsayıldığında Sıfat Sırası Genellemesinin Son-üstü-Son Kısıtının sonuçlarından biri olarak ele alınabileceği gösterilmektedir. Yazı, Son-üstü-Son Kısıtının neden geçerli olduğunu açıklayan dizim-temelli bir analizin betimlenmesiyle sona ermektedir.
Reducing the Pain of Infants due to Vaccine Injection: A Randomized Controlled Trial
Authors: ATEŞ BEŞİRİK Selda , GÖZEN Duygu 
Published: June 2022

Objective: This study was conducted as a randomized controlled and experimental to compare the effect of breastfeeding and distraction methods on vital signs, pain level, and the duration of crying due to vaccine injection in healthy infants.
Methods: The population of the study consisted of 120 infants between 1 and 12 months of age who had met the inclusion criteria. The sample group was randomized and divided into two groups. The control group was breastfeed according to clinical procedure, including 58 infants, and the distraction group was include 62 infants. For both groups, the oxygen saturation (SpO2), heart rate (HR), crying duration, and pain scores were compared both before and following vaccination sessions.
Results: The vaccination pain scores of the infants from the distraction group (4.39±2.18) were significantly lower than those of the breastfeeding group (7.05±1.55; p=0.001). The post-vaccination SpO2 was higher in infants in distraction group; whereas, HR was lower in this group compared to the breastfeeding group. The post-vaccination crying durations of those in the distraction group were also shorter than those in the breastfeeding group.
Conclusion: The distraction method is adopted by the use of a toy has been found to be effective in decreasing the acute pain during vaccine administrations.
In vitro Cartilage Regeneration Regulated by a Hydrostatic Pressure Bioreactor Based on Hybrid Photocrosslinkable Hydrogels
Authors: Zhao Xintong , Hua Yujie , Wang Tao , Ci Zheng , Zhang Yixin , Wang Xiaoyun , Lin Qiuning , Zhu Linyong , Zhou Guangdong 
Published: June 2022

Because of the superior characteristics of photocrosslinkable hydrogels suitable for 3D cell-laden bioprinting, tissue regeneration based on photocrosslinkable hydrogels has become an important research topic. However, due to nutrient permeation obstacles caused by the dense networks and static culture conditions, there have been no successful reports on in vitro cartilage regeneration with certain thicknesses based on photocrosslinkable hydrogels. To solve this problem, hydrostatic pressure (HP) provided by the bioreactor was used to regulate the in vitro cartilage regeneration based on hybrid photocrosslinkable (HPC) hydrogel. Chondrocyte laden HPC hydrogels (CHPC) were cultured under 5 MPa HP for 8 weeks and evaluated by various staining and quantitative methods. Results demonstrated that CHPC can maintain the characteristics of HPC hydrogels and is suitable for 3D cell-laden bioprinting. However, HPC hydrogels with concentrations over 3% wt% significantly influenced cell viability and in vitro cartilage regeneration due to nutrient permeation obstacles. Fortunately, HP completely reversed the negative influences of HPC hydrogels at 3% wt%, significantly enhanced cell viability, proliferation, and extracellular matrix (ECM) deposition by improving nutrient transportation and up-regulating the expression of cartilage-specific genes, and successfully regenerated homogeneous cartilage with a thickness over 3 mm. The transcriptome sequencing results demonstrated that HP regulated in vitro cartilage regeneration primarily by inhibiting cell senescence and apoptosis, promoting ECM synthesis, suppressing ECM catabolism, and ECM structure remodeling. Evaluation of in vivo fate indicated that in vitro regenerated cartilage in the HP group further developed after implantation and formed homogeneous and mature cartilage close to the native one, suggesting significant clinical potential. The current study outlines an efficient strategy for in vitro cartilage regeneration based on photocrosslinkable hydrogel scaffolds and its in vivo application.
Synthesis and Anticancer Activity of Rhopaladins’ Analog RPDPD Against the HeLa Human Cervical Cancer Cell Line
Authors: Chen Feng , Wang Hong-Mei , Kong Ling-Qi , Chen Qin-Hua , Ke Li-Na , Dai He-Liu , Zeng Xiao-Hua 
Published: June 2022

Heterocyclic compounds were widely used in many domains; pyrrolidone is a derivative of heterocycles that can be used to synthesize anticancer drugs. A new fluorine-containing rhopaladins’ analog(E)-2-(4-bromobenzoyl)-N-(tert-butyl)-4-(4-fluoro benzylidene)-5-oxo-1-propylpyrrolidine-2-carboxamide (RPDPD for short) of 2-aroyl-4-arylidene-5-oxopyrrolidine derivative was synthesized by the one-pot synthesis method and evaluated for its anti-tumor activity in vitro via CCK8 assay and annexin V/propidium iodide (PI) staining of HeLa cells. The results exhibited that compound RPDPD has inhibited the proliferation of HeLa in a dose-dependent manner with an IC50 of 24.23 μmol/L (p &lt; 0.05) and has low hepatotoxicity with an IC50 of 235.6 μmol/L (p &lt; 0.05) to normal hepatocyte LO2 cells. The apoptotic assay demonstrated that compound RPDPD has induced apoptosis in HeLa cells (from 14.26 to 23.4%, p &lt; 0.05). qRT-PCR results showed that the compound RPDPD could inhibit the expression of oncogene E6/E7 mRNA (p &lt; 0.05) of human papillomavirus (HPV). The results of Western blot showed that the compound RPDPD promoted the expression of TIMP3 protein and inhibited the expression of MMP3 (p &lt; 0.05). In conclusion, the compound RPDPD can inhibit the proliferation of cervical cancer cells and induce the apoptosis of cervical cancer cells, and its mechanism may be related to the inhibition of E6 mRNA and E7 mRNA expressions, and the anticancer effect of the compound RPDPD on cervical cancer is closely related to the TIMP3/MMP3 signaling axis.
Clinical Profile and Prognosis of Hereditary Transthyretin Amyloid Cardiomyopathy: A Single-Center Study in South China
Authors: Wang Shuai , Peng Wenke , Pang Min , Mao Ling , Peng Daoquan , Yu Bilian , Wu Sha , Hu Die , Yang Yang , He Jia , Ouyang Mingqi 
Published: June 2022

BackgroundHereditary transthyretin amyloid cardiomyopathy (ATTR-CM) is a genotypically heterogeneous disorder with a poor prognosis. There is limited literature describing the variants responsible for ATTRv in areas outside the United State, the United Kingdom and Europe. This study was performed to describe the clinical characteristics and genotypic profiles of this disease in South China.MethodsThis was a single-center retrospective study that evaluated 29 patients with a confirmed diagnosis of hereditary transthyretin amyloid cardiomyopathy enrolled from January 2016 to November 2021.Results93.1% patients were male and the median age of symptom onset was 53 (46, 62.5) years old. The initial manifestations of ATTR-CM were cardiovascular symptoms (55.2%), neuropathy (41.4%) and vitreous opacity (3.4%). Phenotypes at diagnosis were mixed (82.8%), predominant cardiac (6.9%), neurological (6.9%) and ophthalmic (3.4%). Poor R-wave progression (41%), pseudo-infarct (31%) and low-voltage (31%) patterns were common findings on electrocardiogram. Unexplained increased wall thickness was observed in all 29 patients, with mean septal and posterior wall thicknesses of 14.25 ± 6.26 mm and 15.34 ± 2.84 mm, respectively. Diastolic dysfunction was also seen in all 29 patients, and 17 (58%) had a restrictive fill pattern at diagnosis. Nine different missense mutations of the TTR gene were found in 29 patients from 23 families, with c.349G&gt;T (p.Ala117Ser) the most common mutation. The median survival time after diagnosis was 47.6 (95% CI 37.9-57.4) months, with 1, 3 and 5-year survival rates of 91.2%, 74% and 38% respectively. Patients with advanced heart failure (National Amyloidosis Staging stage II/III) had worse survival than stage I [Breslow (Generalized Wilcoxon), χ2 = 4.693, P = 0.03)].ConclusionsATTR amyloidosis genotypes and phenotypes are highly heterogeneous. Advanced heart failure predicts a poor prognosis. Understanding the different clinical profiles of ATTR cardiac amyloidosis with different genotype is important to its early recognition.
Examining Social Media Experiences and Attitudes Toward Technology-Based Interventions for Reducing Social Isolation Among LGBTQ Youth Living in Rural United States: An Online Qualitative Study
Authors: Escobar-Viera César G. , Choukas-Bradley Sophia , Sidani Jaime , Maheux Anne J. , Roberts Savannah R. , Rollman Bruce L. 
Published: June 2022

PurposeLesbian, gay, bisexual, transgender, and queer (LGBTQ) youth living in rural areas who feel isolated are at high risk of depression and suicidality. Given the lack of support in their offline communities, many rural-living LGBTQ youth turn to social media for social support. In this qualitative study, we examined rural LGBTQ youth's social media experiences and attitudes toward technology-based interventions for reducing perceived isolation.MethodIn Spring 2020, we conducted online interviews with LGBTQ youth aged 14-19, living in rural areas of the United States, who screened positive for perceived social isolation (n = 20; 11 cisgender sexual minority, 9 transgender). Interviews examined (1) supportive social media experiences, (2) personal strategies to improve social media experiences, and (3) perspective on potential digital intervention delivery modalities. Data were analyzed using thematic analysis.FindingsRelated to supportive content and interactions, themes included (1) positive representation of and connecting with LGBTQ groups on social media are important; (2) content from people with shared experience feels supportive, and (3) lack of feedback to one's experiences is isolating. Regarding personal strategies to improve social media experiences, themes were (1) selecting platforms to connect with different audiences helps make for a more enjoyable social media experience, and (2) several social media platform features can help make for a safer social media experience. Youth discussed advantages and disadvantages of intervention delivery via a mobile app, social media pages or groups, conversational agents (chatbots), and a dedicated website.ConclusionViewing positive representation of and connecting with LGBTQ groups, content from people shared experiences, and utilizing a wide array of platform features to increase the likelihood of positive connections are key to a positive social media experience among this group. Combining delivery modalities is key to engaging rural-living LGBTQ youth in digitally delivered support interventions to reduce perceived isolation. Our results inform future intervention research and conversations about social determinants of health between providers and rural LGBTQ patients.
Evaluation of Three Blended Learning Courses to Strengthen Health Professionals' Capacity in Primary Health Care, Management of Sexual and Reproductive Health Services and Research Methods in Guinea
Authors: Millimouno Tamba Mina , Delvaux Thérèse , Kolié Jean Michel , Kourouma Karifa , Van Bastelaere Stefaan , Tsunami Carlos Kiyan , Béavogui Abdoul Habib , Garcia Marlon , Van Damme Wim , Delamou Alexandre 
Published: June 2022

BackgroundThree blended courses on Primary Health Care (eSSP), Management of Sexual and Reproductive Health Services (eSSR), and Research Methods (eMR) were developed and implemented between 2017 and 2021 by the Maferinyah National Training and Research Center in Rural Health, a training and research institution of the Ministry of Health in Guinea. The study objectives were to evaluate the reasons for dropout and abstention, the learners' work behavior following the training, and the impact of the behavior change on the achievements of learners' organizations or services.MethodsWe evaluated the three implemented courses in 2021, focusing on levels 3 and 4 of the Kirkpatrick training evaluation model. Quantitative and qualitative data were collected through an open learning platform (Moodle), via an electronic questionnaire, during the face-to-face component of the courses (workshops), and at learners' workplaces. Descriptive statistics and thematic analysis were performed for quantitative and qualitative data, respectively.ResultsOut of 1,016 applicants, 543 including 137 (25%) women were enrolled in the three courses. Over the three courses, the completion rates were similar (67–69%) along with 20–29% dropout rates. Successful completion rates were 72% for eSSP, 83% for eMR and 85% for eSSR. Overall success rate (among all enrollees) ranged from 50% (eSSP) to 58% (eSSR). The majority (87%) of the learners reported applying the knowledge and skills they acquired during the courses through activities such as supervision (22%), service delivery (20%), and training workshops (14%). A positive impact of the training on utilization/coverage of services and increased revenues for their health facilities were also reported by some trainees.ConclusionThese findings showed fair success rates and a positive impact of the training on learners' work behavior and the achievements of their organizations.