bluuebunny/crossref_metadata_2025_split huggingface dataset:
Coronary Angiography and Percutaneous coronary Intervention in Anomalous Origin of Right Coronary Artery Arising from the Left Sinus of Valsalva
Authors: Poudel Chandra Mani , Gajurel Ratna Mani , Shrestha Hemant , Devkota Surya , Thapa Sanjeev , Khanal Rajaram , Shakya Smriti , Manandhar Bhawani , Yadav Vijay 
Published: November 2022

Background and Aims: To assess the difficulties encountered while performing coronary angiography and percutaneous coronary intervention in anomalous right coronary artery arising from the left sinus of Valsalva.
Methods: Between January 2016 and December 2020, a total of 23 patients underwent coronary angiography and eight underwent percutaneous coronary intervention for an angiographic significant lesion in the anomalous right coronary artery arising from the left sinus of Valsalva. The vascular approach, usage of catheters, fluoroscopic time, and the amount of contrast used were also assessed.
Results: Among 6000 coronary angiography and 1500 percutaneous coronary intervention performed, 33 patients (0.55%) had right coronary artery arising from the left sinus of Valsalva. Altogether, 14 patients had type-A, seven had Type-B, eight had Type-C, and four had Type-D anomalous right coronary artery arising from the left sinus of Valsalva. Coronary Angiography was accomplished with the Tiger catheter in 13 patients, Judkins left JL in 8 patients, and Extra-backup (XB3) in one patient. In the percutaneous coronary intervention group, cannulation was done with Judkins left (JL), Amplatz left (AL), and XB in five, two, and one patient respectively and among five type-A patients, four were cannulated with JL and one with XB; one Type-B with JL4; and two Type-C with AL2. The mean fluoroscopic time and contrast volume consumption for coronary angiography and percutaneous coronary intervention were 9.9 minutes and 47 minutes respectively and 63ml and 229 ml respectively.
Conclusion: Coronary intervention of anomalous right coronary artery arising from the left sinus of Valsalva is difficult due to inappropriate selection of guide catheter and is associated with a higher both mean fluoroscopic time and contrast volume. Radial route is equally effective for successful procedure.
Director's Modeling of Art Project Based on Jacques Offenbach's Opereta "The Key on the Pavement"
Authors: Petrenko Oksana 
Published: November 2022

The author considered the modern trends in the development of the operetta theater under the influence of a change in its paradigm. The main elements of the play's design are analyzed from the point of view of the director's vision of a creative graduate student. The content of the director's expansion of the libretto of Jacques Offenbach's operetta "The Key on the Pavement" is clarified, which consists in adding inserted episodes in order to modernize the work and so to dynamize it by finding new colors, namely: the prologue - an interactive scene of the meeting of the audience by mimance artists in the hall of the theater for direct involving the audience in the theatrical action and the dance-pantomime scene during the overture with the greeting of the newlyweds and the handing over of wedding gifts. The director's means of expression, the nature of their synthesis in an artistic project are outlined. The director's model of the artistic project based on J. Offenbach's operetta "The Key on the Pavement" in the author's vision of a creative graduate student has been determined. The content of the director's expansion of the libretto of J. Offenbach's operetta "The Key on the Pavement" is clarified, which consists in adding some episodes this innovation gives the operetta a modern structure that attracts the contemporary audience. The main elements of the director's idea of the play were revealed: scenographic solution, mise-en-scène drawing, director's characterization of the personages with the development of their psychological portraits, supertasks and artistic images of the characters of the play. The director's idea of the project was formed in the context of the composer's conceptual vision for a harmonious combination of form and content. It has been proven that the most vivid directorial means of expressiveness of contemporary theater art is the use of multimedia and the latest art technologies. Emphasis is placed on their compliance with the requirements of the time, on special attention to the balance and expediency of their use, harmony with the original work. The vectors of further scientific research in the context of modernization of operetta performances, which are caused by the change of the theater paradigm and the search for modern directorial means of expression to increase the impact on the audience, are predicted.
FRAME AS A COGNITIVE MODEL OF IRONIC MEANING
Authors: Prystupa Vitaliy V. 
Published: November 2022

The concept of irony seems erroneously easy for understanding on the level of ‘folk linguistics’. Nevertheless, the cognitive aspects of perception and comprehension pose the question of ironic blindness, that is when the interlocutors cannot decipher or retrieve the implied meaning. The problem of adequate comprehension of irony arises to its structural, linguistic and cognitive structures. If so-called direct or negative irony is more obvious for the interlocutors and thus is perceived almost unmistakably, the positive irony creates numerous problems for them. This study investigates the irony comprehension from the cognitive point of view. Based on the analyzed in the paper text fragments the author shows that in the lingo-cognitive approach to understanding irony, both linguistic and non-linguistic levels are reflected. It provides an analysis of linguistic factors in their connection with the organization of the conceptual system. The starting point for the formation of ironic discourse, particularly in English journalistic texts, is the polysegmental concept of IRONY, objectified by various language tools of different levels. The explication of ironic discourse in English-language journalism occurs through the ironic framing of the message, serving as a cognitive model of ironic meaning. The paper proposes the term ‘ironic frame’ as a designation of an integrated / ‘hybrid’ language-thinking structure that arises in the mind of a native speaker due to the interpenetration and interaction of several mental spaces, associated with a verbal expression of negative, disapproving, critical or skeptical attitude to the object of irony.
LEXICAL POLYSEMY IN DIACHRONY AND SYNCHRONY
Authors: Yurchenko Nataliia S. 
Published: November 2022

The paper considers the peculiarities of the origin and functioning of lexical polysemy in different languages, in particular in Ukrainian, German and English. The author examines discourse of Ukrainian scholars in terms of the study of the polysemic words causes, the relationship between the meanings of polysemic words, the distinction between the phenomena of polysemy and homonymy, the linguistic functions of polysemic units. The opinion that the polysemy of words in different languages is not an accidental phenomenon was justified. It was emphasized that the presence of a limited amount of vocabulary, which is associated with the qualitative features of the physiological mechanism of the human brain (memory), leads to the emergence of ambiguous words. Each polysemic word has a relatively constant semantic core, independent of the context, which is a necessary basis for the functioning of polysemic units, and it ensures the semantic integrity of the word. Although the set of meanings of a polysemantic word in different languages differs, the phenomenon of polysemy is universal for all languages. It allows expanding the linguistic nominative potential and, given the cost-effectiveness of the language, to avoid increasing the number of lexical items. The need to determine the nature of the lexical meaning of a word at the level of language and speech, its frameworks, the concept of semantic structure of a polysemic word, the semantic core of the word, connections, relationships and functioning of different meanings was described. The major factors that influence semantic changes in a polysemic word and consist in various changes in the process of historical development of languages, in which words acquire new meanings, were characterized. It leads to the emergence of more semantic aspects, which are historically fixed in the minds of the people in connection with the relationship of words with certain phenomenon. The effectiveness of the phenomenon of polysemy as a means to increase the linguistic potential of language, due to the formatting of existing values and the emergence of new ones in the process of active development of the lexicon is substantiated.
MUSICAL DIMENSIONS OF QUALITY JUDGEMENTS IN LITURGICAL TRANSLATION
Authors: Shmiher Taras V. 
Published: November 2022

The paper is dedicated to the issues of how translation quality assessment can deal with the musical aspects of liturgical praxis. It is not limited to the matters of melody and isosyllabism (which partially overlap with the theory of verse translation), but it has also to cover the issues of functionality, perception and reception (which are integrated in translation sociology and criticism). The study consists of three foci: singability and melody (isosyllabism and local chants, collective and individual creativity), historicism (hidden interpretations, functional censorship) and phonetic and semantic prosody (problems of subjectivist perception, churchly interventions, modulations of poetic texts for liturgical use). The problem of relay translation looks very unusual: although all liturgical texts came from the same language (Patristic Greek), vernacular believers receive their national texts which were translated via the mediating language (Latin or Church Slavonic, or even more languages). The main text of the analysis is the Paschal Troparion (in the Greek, Church Slavonic, Ukrainian, Polish, and English versions), but observations over other various liturgical texts are included. The juxtaposition of the Roman and Byzantine Rites shows how great the role of vocal music is in both rites and how attentively the ecclesiastical authorities cherished the sacred music for the propaganda of ecumenical moral dogmas.
Pharmacodynamics of Xylazine, Acepromazine and Diazepam on Various Physiological Parameter in Rabbits
Authors: Mian Saeed Sarwar  , Naimat Ullah Khan  , Khan Humayun , Ali Hazrat , Gohar Ali , Usman Tahir 
Published: November 2022

The aim of the present study was to explore the effect of three selective sedative/tranquilizer drugs i.e. Xylazine(XZ), Acepromazine(AC), and Diazepam(DZ) on normal physiological parameters such aspulse, respiration, body temperature and serum glucose.All the three drugs i.e. Xylazine, Acepromazine, and Diazepam were used at the dose rate of 8mg/kg, 5 mg/kgand diazepam1mg/kg respectivelythrough intramuscular route(I.M.)in six healthy rabbits of non-descriptive Before administration of drugs all physiological parameters were recordedPulse, respiration and body temperature shows significant (0.05) decrease after administration of these drugs. Maximum decrease in the pulse rate was recorded at 60, 30 and 45 minutes and were returned to its normal at 150, 135 and 135 minutes with XZ, AC and DZ Low respiratory rate was noted at 45, 30 and 75 minutes and were returned to the non-significant level at 105, 90 and 135 minutes with XZ, AC and DZ Body temperature decreased to its maximum at 45, 30 and 60 minutes and returned to its normal at 120, 120 and 135 minutes after administration of XZ, AC and DZ Onset of sedation started at 83±0.30, 6.16±0.47 and 3.83±0.30 minutes with XZ, AC and DZ Significant difference were found in XZ and AC, DZ and AC at 0.05 but there was no significant difference between XZ and Total duration of sedation was 101.17±1.07, 00±1.87 and 90.00±1.29 with XZ, AC and DZ respectively.XZ and DZ significantly (P< 0.05) increase serum glucose level while AC have no significant effect on serum glucose From the overall finding all the three drugs were were found safe for rabbits but XZ shows the best results.
Epidemiology of Urinary Incontinence among Females of Age 20-65 years
Authors: Kousar Raheela , Islam Farooq , Raza Asim , Altaf Rabbeya 
Published: November 2022

Background: urinary incontinence is said to be a condition in which there is involuntary urine loss. Although it is a common clinical condition among females whether it is stress urinary incontinence, urge urinary incontinence or mixed it leads to social embarrassment and isolation which affect their activities of daily living yet the exact prevalence is unknown as it depends upon different risk factors. In Pakistan there is lack of literature which could explain its dependency on varying risk factors.
Objective(s): To evaluate prevalence of urinary incontinence among females of age 20-65 years.
Methodology: A cross-sectional research with a sample size of 377 females from the general population of Gujrat District was done. Statistical Package of Social Sciences (SPSS) was used to analyze the obtained data. Findings were then interpreted using Chi-square test.
Results: The results have been obtained after analyzing the data collected from 377 females. Prevalence of UI was 75.3% No significant associations were found as P-values were ?0.05.
Conclusion(s): This study shows that urinary incontinence is a very common issue in females and it varies with age , parity, mode of delivery and menopause
Key words: menopause, parity, Stress urinary incontinence, urge urinary incontinence, Urinary incontinence
Cognitive Changes in the Patients of Breast Cancer Receiving Chemotherapy
Authors: Tuba Bari  , Zubaida Umar  , Ata Ur Rehman  , Aftab Nazir  , Shubana Kausar  , Fozia Zahur Malik  
Published: November 2022

Objective:To determine the prevalence of cognitive disorders in patients suffering from breast cancer receiving chemotherapy treatment in Mayo Hospital Oncology ward. Subjects and methods: A cross-sectional type of study was conducted in Mayo Hospital Lahore from April 2017 to June 2017 in order to know about the effects of chemotherapy on cognitive dysfunction in female breast cancer patients.The study included 55 participants , all of them were receiving chemotherapy at the time the research was conducted. A questionnaire was formulated and got filled. The final data was analyzed with the help of SPSS having version 21 and the descriptive statistics e.g percentage and frequencies were achieved. Results:Different measures to test the cognitive functions of patients were used.The analysis of data demonstrated significant relation between increasing age and deterioration of words registration functions,verbal functions and clock drawing interpretation functions of brain. (p = .001 , p=.015 , p=.006 respectively) .While financial management skills of the patients seemed to be unaffected by chemotherapy ( p =.066).Conclusion :These results of this study clearly showed serious derangement in cognitive functions of the patients receiving chemotherapy for breast cancer.Moreover age and pre-treatment natural cognitive reserve are the important predictors of magnitude of deterioration.
Variable Doses of Nigella sativa in Isoniazid Induced Liver Toxicity in Rabbits
Authors: Abdullah Jan Panezai  , Moosa Khan  , Syed Muhammad Ishaque  , Raheem Ullah  , Ahmad Ali Khan  , Noshaba Rahat  
Published: November 2022

Objective: To evaluate the effect of various doses of Nigella sativa in isoniazid induced liver biochemical changes in Rabbits.
Study design: Animal study
Place of study: Department of Pharmacology and Therapeutics in collaboration of Animal house BMSI, JPMC Karachi.
Method:
In this animal study, 48 (N) healthy rabbits of either sex were randomly selected and equally divided in four groups (12 in each). Group I, was given only healthy diet. Group II, given Isoniazid at 50mg/kg body weight per day orally. Group III, was given Isoniazid 50mg plus Nigella sativa 500 mg/kg body weight/day orally and Group IV, given Isoniazid 50mg plus Nigella sativa 1gm/kg body weight/day orally. Treatment duration was 20 days. Liver biochemical changes i-e, Serum Total Bilirubin, ALT and AST were investigated on 00 and 21 days respectively. The data was collected on designed proforma and assessed statistically using SPSS version 16 and paired T- Test was applied.
Results:
In Group I the liver biochemical changes were non-significant on 00 and 21 days. (S. Total Bilirubin, p value = 0.06, ALT, p = 0.09 & AST, p = 0.74). Group II the parameters were significantly raised, when 00 and 21 days were compared. (S. Total Bilirubin p = 0.00, ALT p = 0.00 & AST p = 0.00). In Group III the liver biochemical changes noted both significant and non-significant when compared between 00 and 21 days. (S. Total Bilirubin p = 0.06, ALT p = 0.00 & AST p = 0.74). Group IV the liver biochemical changes were non-significant when compared between 00 and 21 days. (S. Total Bilirubin p = 0.06, ALT p = 0.09 & AST p = 0.74)
Conclusion:
Nigella sativa showed protective role on isoniazid induced liver toxicity in rabbits.
The Frequency of Lymphocele and its Management in Post Renal Transplant Patients in a Tertiary Care Hospital of Khyber Pakhtunkhwa, Pakistan
Authors: Hazratullah  
Published: November 2022

Objective
To assess the frequency of lymphocele and its management in patients with live renal transplant.
Introduction
Renal transplant is the treatment of choice for patient with ESRD. Although it improve quality and increase life expectancy but it is not without major and minor complications one of that complication is lymphocele that cause that cause severe morbidity and even graft dysfunction. We conducted this study to find the frequency of lymphocele in patients undergoing renal transplant.
Material and Methods
This is a retrospective study conducted in the Institute of Kidney Diseases and Transplant. The files of all those patients were analyzed who underwent live donor renal transplant from Jan 2015 to July 2020. The demographic and all relevant data were entered in a proforma. For analysis we entered data in SPSS version .

Results
From Jan 2015 to July 2020 42 renal transplants were performed. Male patients were 32 (76 %) and female were 10 (23.8%) ratios male to female 3.2 to 1. Mean age 37.5 years (range 50 to 25 years). Of these 5 (11.9%) patients developed lymphocele 3 patients (7.1%) developed mild lymphocele without any renal dysfunction that treated conservatively while two (4.7%) presented with hydronephrosis and renal dysfunction one of this respond to percutaneous aspiration and tetracycline installation while one after failed response to percutaneous aspiration and sclerotherapy treated by laparoscopic interaperitoneal drainage.
Conclusion
Lymphocele is one of the common cause of renal transplantation that respond to different treatment modalities range from conservative to minimally invasive or major intervention in the form of open surgical technique or laparoscopic intervention.
Hematological And Clinical Analysis of Hepatitis B Patients from Quetta, Pakistan
Authors: Abdul Latif  , Sadia Sabir  , Saima Iram  , Pari Gul  , Asma Yousafzai  
Published: November 2022

Background: Hepatitis B Virus (HBV) infection is still a serious worldwide health concern. The primary mechanisms of HBV transmission in Pakistan include the use of infected tools in medical and dental practices, unsafe blood transfusion, and a family history of HBV infection. Pakistan has a high HBV prevalence, with 4.55 million persons affected. The cause for this might be a lack of sufficient health facilities, a bad economic situation, and insufficient knowledge regarding the spread of infections such as HBV.
Aim of the study: The goal of this study was to look at the possible risk factors that may lead to HBV infection and analysis of Hematological and liver function tests which are two tests that are used to determine the health of a person.
Methods: Blood samples from 244 individuals infected with HBV infection (including both males and females) were collected and processed for complete blood count and liver function analysis. General characteristics were recorded interview and questionnaire.
Results: A total of 244 HBV-positive patients were included in the study. Their ages were range from 17-78 years. The HBV rate was higher in males 175 (71.7%) and 69 (28.3%) in females. Out of one hundred forty-four patients, 143 (58.60%), individuals were from rural areas and 101 (41.60 %) were from urban areas. majority of the individuals 148 (60.7%) were married and 87 (35.7%) were unmarried. According to their education, most of the participants 101 (41.4%) were illiterate and only 61 (25.0%) had a higher level of education. Dental history and smoking habits were recorded in 71 (29.1%) patients respectively. Similarly, a family history of hepatitis B infection was recorded in 51 (20.9%) and only 15 (6.1%) had a blood transfusion history.
Conclusion: In rural areas of Quetta, Balochistan, Pakistan, the current study demonstrated a significant incidence of HBV infection. The observed prevalence is gender and age-dependent, possibly because of their increased exposure to common risk factors. To prevent the spread of HBV infection, it is advised that people be made aware of the potential risk factors and that vaccination be extended in high prevalent regions.
Status of Suleman Markhor (Capra falconeri Jerdoni) in Ziarat National Park, Balochistan to Identify its Negative Incentive Along with Conservation Measures
Authors: Sadia Jaffar  , Nosheen Rafiq  , Jafar Ali Baloch  , Muhammad Naseem Jaffar  , Hina Ali Ahmed  , Tahir Habib  , Syeed Inamullah  , Kiran Aslam  , Ehsan Ullah Jaffar  , Hasil Khan Baloch  , Sundas Tariq  , Muhammed Niaz Khan Kakar  
Published: November 2022

ABSTRACT:
The present study was conducted to investigate the population growth pattern, population status examination of negative elements that decreased their population and formation of positive actions for conservation of Suleman markhor "(Capra falconeri jerdoni) ? in Ziarat National Park. The data in present work was assembled undeviatingly through occasional survey and meetings from the forest department, from the local community and wildlife department. Results showed that the number of Suleman markhor based on actual sighting is moderately subsidence as compared to those reported in 2017 by IUCN Pakistan. Density decreased due to climatic factors environmental factors, rise in hunting, food absence and drought. Thus it is recommended that taxonomic status persistence the flora and fauna of Ziarat park inference the wildlife rules against over hunting, conduction of surveys, proper vaccinations of animals, habitat hotbeds, dispersal species through GIS maps, investigation of genetic makeup through crossing different spices of others goats are mandatory for unusually unique species of Markhor in Ziarat National park, that is need of zoological point of view.