bluuebunny/crossref_metadata_2025_split huggingface dataset:
Access to information on oral hygiene and mothers' practices of children with microcephaly caused by Zika virus
Authors: Vaz Fernando Flávio Souza , Sobrinho Adriano Referino da Silva , Athayde Fernanda Regina Ribeiro Santos , Carvalho Marianne de Vasconcelos , Sette‐de‐Souza Pedro Henrique , Ferreira Stefânia Jeronimo 
Published: September 2022

AbstractObjectiveTo verify whether access to information about oral hygiene influenced the practices of caregivers of children with microcephaly caused by Zika virus (ZIKV).MethodsA case series study was developed at the Mens Sana Rehabilitation Center, in the municipality of Arcoverde, Pernambuco, Brazil. The study universe included the mothers of 32 children with microcephaly caused by Zika virus. Data collection took place in June 2018 and was carried out through a structured questionnaire. The variables studied comprised socioeconomic issues, habits, diet, and knowledge about oral hygiene. Fisher's Exact and Pearson's Chi‐square tests were used with a significance level of 5%.ResultsOut of 32 individuals eligible to participate in the study, only 27 were selected. Most mothers reported receiving information about oral hygiene from their infants (63.0%). Fisher's Exact and Pearson's Chi‐square tests showed that access to oral hygiene information was associated with mother's education, family income, regular visits to the dentist, frequency of tooth brushing, age at which the infant started brushing, and brushing time (p < 0.05).ConclusionAccess to information about oral hygiene positively influenced the oral health care of mothers with their children with microcephaly caused by ZIKV.
Impact of serum vitamin D levels on periodontal healing outcomes: A preliminary cohort study
Authors: Ribeiro Lívia Silva Figueiredo e , Araujo Nara Santos , Zilli Vieira Carolina Letícia , dos Santos Jean Nunes , Cury Patricia Ramos 
Published: September 2022

AbstractObjectiveTo evaluated the relationship between serum vitamin D levels and periodontal healing outcomes in patients with mild or moderate periodontitis.MethodsSerum vitamin D levels and periodontal pockets and gingival bleeding were evaluated in 51 patients before and 6 months after non‐surgical periodontal treatment. At‐test and chi‐square test were used to analyse the data (p ≤ 0.05).ResultsThe mean reduction of periodontal pocket depth was statistically significant higher in patients with vitamin D ≥30 ng/ml than those with <30 ng/ml (CI = −0.23–0.42,p = 0.05), but not clinically significant. Vitamin D level was not associated with the percentage of sites of gingival bleeding on probing at the final evaluation (OR = 0.58, 95% CI = 0.17–1.99,p = 0.39).ConclusionLower serum vitamin D level was associated with a slightly reduced periodontal healing after non‐surgical periodontal therapy, which should be further investigated in a larger population.
IRREVERSIBILITY AND MONITORING IN DYNAMIC GAMES: EXPERIMENTAL EVIDENCE
Authors: Lee Eungik , Choi Andrew , Choi Syngjoo , Guéron Yves 
Published: September 2022

AbstractThis article provides experimental evidence on the impacts of irreversibility and imperfect monitoring on the efficiency and the equity of a repeated public goods game. We find that irreversibility and imperfect monitoring both lead to inefficient and unequal outcomes through different channels. Irreversibility lowers public goods contribution in earlier periods and makes the initial‐period contribution gap between two players long‐lasting. Imperfect monitoring hampers conditional cooperation and persistently reduces group contribution. A finite mixture estimation with conditional cooperators provides a coherent account of the treatment effects.
Fast‐flowing LBE corrosion of the SiC pump impeller: Numerical and experimental investigations
Authors: Li Xianhui , Zeng Xian , Zhao Zhanchong , Zhang Xiaoxin , Yan Qingzhi , Zhang Youyuan , Wen Yuying , Yang Xuanbing , Mao Feng 
Published: September 2022

AbstractIn order to determine the stress state and the specific dynamic corrosion behaviors of the cooling pump impeller in the liquid lead‐bismuth eutectic alloy (LBE), the numerical and the experimental investigations on the fast‐flowing LBE corrosion behaviors of the SiC impeller were conducted. The distributions of stress and displacement of the SiC impeller were simulated, and then the microstructure and mechanical properties of the corroded impeller were characterized. The results indicated that the SiC impeller met the strength requirement of 1000 rpm in LBE, and the dynamic LBE corrosion had little effect upon structure safety of the SiC impeller. The maximum stresses of the SiC impeller without and with LBE loading were .452 and 9.736 MPa, respectively. The maximum displacements of the SiC impeller without and with LBE loading were 76.385 and 4.096 μm, respectively. The LBE loading reduced the axial displacement of the impeller and acted as an impeller stabilizer to some extent. Blade elongating and flapping were the main vibration mode of the SiC impeller. The mechanical properties of the SiC impellers before and after corrosion were basically the same.
The Boston ASL Template and Simulator: Initial development and implementation
Authors: Taso Manuel , Munsch Fanny , Alsop David C. 
Published: September 2022

AbstractBackground and purposeTemplates are a hallmark of image analysis in neuroimaging. However, while numerous structural templates exist and have facilitated single‐subject and large group studies, templates based on functional contrasts, such as arterial spin labeling (ASL) perfusion, are scarce, have an inherently low spatial resolution, and are not as widely distributed. Having such tools at one's disposal is desirable, for example, in the case of studies not acquiring structural scans. We here propose an initial development of an ASL adult template based on high‐resolution fast spin echo acquisitions.MethodsHigh‐resolution single‐delay ASL, low‐resolution multi‐delay ASL, T1‐weighted magnetization prepared rapid acquisition 2 gradient echoes, and T2 fluid attenuated inversion recovery data were acquired in a cohort of 10 healthy volunteers (6 males and 4 females, 30± 7 years old). After offline reconstruction of high‐resolution perfusion arterial transit time (ATT) and T1 maps, we built a multi‐contrast template relying on the Advanced Normalization Toolbox multivariate template nonlinear construction framework. We offer examples for the registration of ASL data acquired with different sequences. Finally, we propose an ASL simulator based on our templates and a standard kinetic model that allows generating synthetic ASL contrasts based on user‐specified parameters.ResultsBoston ASL Template and Simulator (BATS) offers high‐quality, high‐resolution perfusion‐weighted and quantitative perfusion templates accompanied by ATT and different anatomical contrasts readily available in the Montreal Neurological Institute space. In addition, examples of use for data registration and as a synthetic contrast generator show various applications in which BATS could be used.ConclusionsWe propose a new ASL template collection, named BATS, that also includes a simulator allowing the generation of synthetic ASL contrasts. BATS is available at http://github.com/manueltaso/batsasltemplate.
The empathic personality profile: Using personality characteristics to reveal genetic, environmental, and developmental patterns of adolescents' empathy
Authors: Abramson Lior , Eldar Eran , Markovitch Noam , Knafo‐Noam Ariel 
Published: September 2022

AbstractObjectiveHow do genetic and environmental processes affect empathy during early adolescence? This study illuminated this question by examining the aetiology of empathy with the aetiology of other personality characteristics.MethodIsraeli twin adolescents rated their empathy and personality at ages 11 (N = 1176) and 13 (N = 821) (733 families, 51.4% females). Parents rated adolescents' emotional empathy. Adolescents performed an emotion recognition task, indicating cognitive empathy.ResultsUsing a cross‐validated statistical learning algorithm, this study found emotional and cognitive “empathic personality profiles,” which describe and predict self‐reported empathy from nuanced Big‐Five personality characteristics, or “nuances” (i.e., individual items). These profiles predicted empathy moderately (R2 = 0.17–0.24) and were stable and robust, within each age and between ages. They also predicted empathy in a new sample of older nontwin adolescents (N = 96) and were validated against non‐self‐report empathy measures. Both emotional and cognitive empathy were predicted by nuances representing positive attitudes toward others, trust, forgiveness, and openness to experiences. Emotional empathy was also predicted by nuances representing anxiousness and negative reactivity. Twin analyses revealed overlapping genetic and environmental influences on empathy and the empathic personality profiles and overlapping environmental influences on empathy–personality change.ConclusionsThis study demonstrates how addressing the complexity of individuals' personalities can inform adolescents' empathy development.
Neopestalotiopsis longiappendiculata as the agent of grey blight disease of Camellia spp.
Authors: Wang Qiu‐Tong , Cheng Yuan‐Hui , Zhuo Lan , Wang Yu , Zhou Hao , Hou Cheng‐Lin 
Published: September 2022

AbstractThe grey blight disease is a common disease of tea plants and camellias (Camellia spp.). It is caused by Pestalotiopsis‐like fungi, which were mostly identified as species of Pestalotiopsis and Pseudopestalotiopsis. In this study, four strains of Neopestalotiopsis were isolated from brown and grey‐white spots of leaves of Camellia oleifera and C. sasanqua in China. These strains belong to Neopestalotiopsis longiappendiculata and are characterized by morphology and multi‐loci phylogenetic analysis (ITS‐tef‐tub2). This is the first report of N. longiappendiculata as agent of grey blight disease on Camellia spp. Pathogenicity tests indicated that N. longiappendiculata infects not only Camellia oleifera and Camellia sasanqua but also Eucalyptus polyanthemos and Euonymus japonicas. Given the broad host range and pathogenic nature, it is time to focus on management aspect to control the disease.
Early virologic relapse predicts alanine aminotransferase flares after nucleos(t)ide analogue withdrawal in patients with chronic hepatitis B
Authors: Liem Kin Seng , Chi Heng , Fung Scott , Wong David K. , Yim Colina , Noureldin Seham , Chen Jiayun , de Man Robert A. , Sarowar Arif , Feld Jordan J. , Hansen Bettina E. , Hou Jinlin , Peng Jie , Janssen Harry L. A. 
Published: September 2022

AbstractWhen patients with chronic hepatitis B (CHB) stop nucleos(t)ide analogue (NA) therapy before achieving HBsAg loss, flares often ensue which are challenging to predict early. We determined the incidence, severity, outcome and predictors of flares after NA withdrawal. Forty‐five patients enrolled in an RCT were included; 107 patients from an external, prospective cohort were used for validation. Retreatment criteria were pre‐defined. Pre‐ and post‐treatment predictors of alanine aminotransferase (ALT) flare (>5× ULN) were evaluated by Cox proportional‐hazards regression. Seventy‐two weeks after NA withdrawal, 23/45 (51%) patients had developed >5× ULN and 14 (31%) >20× ULN. Median time to develop ALT >5× ULN was 12 weeks after NA withdrawal. Independent predictors of ALT >5× ULN were male sex (HR [95% CI] 3.2 [1.2–8.9]; p = 0.03) and serum HBV DNA (1.2 [1.0–1.8]; p = 0.03) at Week 6 off‐therapy. Specifically, week 6 HBV DNA >10,000 IU/ml predicted ALT >5× ULN (3.4 [1.4–8.4]; p = 0.01), which was externally validated. In conclusion, this study on post‐treatment flares revealed a high cumulative incidence in CHB. Week 6 HBV DNA >10,000 IU/ml independently predicted flares. The proposed threshold enables prediction of imminent flares in patients who may benefit from closer monitoring and earlier retreatment.
Outcomes of de novo belatacept‐based immunosuppression regimen and avoidance of calcineurin inhibitors in recipients of kidney allografts at higher risk for underutilization
Authors: Patel Ankita , Shertel Tara , Wynd Michael , Wadhera Vikram , Serur David , Schleich Benjamin , Yushkov Yuriy , Goldstein Michael 
Published: September 2022

AbstractTo describe an experience using a protocol using de novo belatacept (DNB) based maintenance immunosuppression in the setting of lymphocyte depletion. A retrospective, observational study was performed on 37 kidney transplant recipients treated with the DNB protocol, which was defined as belatacept initiated within 7 days after a kidney transplant with steroids and mycophenolate with anti‐thymocyte globulin (ATG) induction without concomitant calcineurin inhibitors (CNIs). Patients who received a deceased donor kidney meeting one or more of the following criteria: anticipated cold ischemia time (CIT) greater than 24 h, donation after cardiac death, donor acute kidney injury, and a Kidney Donor Profile Index (KDPI) >85% during the study period were included. Patient survival at 1 year was 97.3% and graft survival was 94.6%. Delayed graft function (DGF) occurred in 40.54% of the patients. Two patients experienced a Banff 1B acute cellular rejection. BK viremia was detected in 32.4% of patients. The mean estimated glomerular filtration rate (eGFR) calculated with the use of modification of diet in renal disease (MDRD) equation at 1 year in the study group was 54.7 ml/min/1.73 m2. We believe that utilization of the DNB protocol, which allows early CNI avoidance, may decrease organ discard rates.
On competitive balance in the group stage of the UEFA Champions League*
Authors: Triguero‐Ruiz Francisco , Avila‐Cano Antonio 
Published: September 2022

AbstractThis article examines competitive balance in the group stage of the UEFA Champions League over the last two decades (1999/2000–2017/2018). Competitive balance is considered both before and after a competition. Have the groups been designed in such a way as to ensure similar levels of competitive balance ex ante? Have the demonstrated strengths (ex post competitive balance) of the different groups been similar over each season? What is the relationship between the competitive balance in the designed groups and that achieved in the same groups after the competition? Are the performance achieved in terms of ex post competitive balance similar to ex ante competitive balance levels? We found that, despite expectations, the groups' ex ante competitive balance was not homogeneous. Although ex ante competitive balance serves as a good predictor, on average, of ex post competitive balance, we observed significant differences at the levels of group and seasons. Therefore, it is possible to improve the design mechanism of the groups that make up the group stage of the champions so that they are composed homogeneously in terms of ex ante competitive balance.
Political opportunity, democracy, and 40 years of protest, 1981–2020: A cross‐national analysis
Authors: Jami Waleed A. , Peoples Clayton 
Published: September 2022

ABSTRACTObjectives: Political opportunity is considered an important factor in any kind of activism, as it represents the context or norms in which a movement operates. Much of the extant literature has focused on political opportunity on a case‐by‐case basis with little consistency in its operationalization. Our goal in this study is to build toward a generalizable measure of political opportunity. To do so, we measured opportunities as democracy and used data from 90+ countries over a 40‐year period, testing the long‐theorized inverse‐U relationship between opportunity and protest.Methods: We used all seven waves of the World Value Survey, which represents much of the world's countries, to examine the link between political opportunity and political behaviors (signing a petition, joining boycotts, and attending peaceful protests).Results: Results confirmed the inverse‐U effect on all three protest behaviors; that is, middle‐of‐the‐road democracies had the highest levels of protest participation, whereas the most representative and most repressive societies had the lowest levels of protest participation.Conclusion: Democracy can be used to represent important dimensions of political opportunity, as it was consistent with the long‐theorized inverse‐U. Moreover, our approach to using democracy, a cross‐national index, may serve as a stepping stone toward a unified and generalizable measure of political opportunity.
Neurodynamic Exercises in College Athletes With Musculoskeletal Pain: A Critically Appraised Topic
Authors: Hattrup Nicholas , Ohlemeyer Kacey , Schmidt Zachary , Gibb Emily , Pfeifer Nicholas 
Published: September 2022

Clinical Scenario: Pain is a common complaint following an orthopedic injury; however, the exact cause of nociception can be complex. Multiple tissues can generate a patient’s complaint of pain, such as the skin, muscle, ligaments, tendon, nerves, and bones. Regarding the somatosensory system, inflammation around the nerve can create pain and alter movement coordination; this information has resulted in increased awareness of neurodynamic assessments and exercises. Neurodynamic assessments and exercises provide a unique paradigm to effectively assess and treat neural tissue, which may not commonly be considered within the traditional orthopedic examination. Clinical Question: In college athletes with musculoskeletal pain and activity impairments, does the use of neurodynamic exercises improve pain or function? Summary of Key Findings: Of the 5 studies, all consisted of chronic injuries with 3 involving upper-extremity pathologies and 2 focusing on lower-extremity pathologies. All 5 studies noted short- and long-term improvement following the incorporation of neurodynamic sliders or tensioners into the treatment plan. Four of the studies had follow-up periods greater than 30 days with sustained improvement on patient outcomes. Only 2 studies described a progression of neurodynamic exercises through sliders and tensioners. Three studies utilized a set/repetition format for exercise prescription, whereas a fourth used a time-based format, and a fifth article utilized both. Finally, 4 studies utilized neurodynamic assessments to identify whether there was a neural component to the patient’s presentation (eg, peripheral nerve mechanosensitivity). Clinical Bottom Line: In individuals with musculoskeletal impairments, evidence exists to support the use of neurodynamic exercises, such as sliders and tensioners, to improve pain and pain-related disability when neural sensitivity exists. Strength of Recommendation: Grade C evidence exists to support the use of neurodynamic exercises in college athletes with a musculoskeletal impairment.
Joint association of food nutritional profile by Nutri-Score front-of-pack label and ultra-processed food intake with mortality: Moli-sani prospective cohort study
Authors: Bonaccio Marialaura , Di Castelnuovo Augusto , Ruggiero Emilia , Costanzo Simona , Grosso Giuseppe , De Curtis Amalia , Cerletti Chiara , Donati Maria Benedetta , de Gaetano Giovanni , Iacoviello Licia 
Published: September 2022

AbstractObjectiveTo jointly analyse two food dimensions, the Food Standards Agency Nutrient Profiling System (FSAm-NPS), used to derive the Nutri-Score front-of-pack label, and the NOVA classification in relation to mortality.DesignProspective cohort study.SettingMoli-sani Study, Italy 2005-10.Participants22 895 participants (mean age 55 (SD 12) years; 48% men).Main outcomes measuresAssociations between dietary exposures and mortality risk, assessed using multivariable cause specific Cox proportional hazard models controlled for known risk factors.ResultsA total of 2205 deaths occurred during 272 960 person years of follow-up. In the highest quarter of the FSAm-NPS index compared with the lowest quarter, multivariable adjusted hazard ratios for all cause and cardiovascular mortality were 1.19 (95% confidence interval 1.04 to 1.35; absolute risk difference 4.3%, 95% confidence interval 1.4% to 7.2%) and 1.32 (1.06 to 1.64; 2.6%, 0.3% to 4.9%), respectively. The hazard ratios were 1.19 (1.05 to 1.36; absolute risk difference 9.7%, 5.0% to 14.3%) and 1.27 (1.02 to 1.58; 5.0%, 1.2% to 8.8%), respectively, for all cause and cardiovascular mortality when the two extreme categories of ultra-processed food intake were compared. When these two indices were analysed jointly, the magnitude of the association of the FSAm-NPS dietary index with all cause and cardiovascular mortality was attenuated by 22.3% and 15.4%, respectively, whereas mortality risks associated with high ultra-processed food intake were not altered.ConclusionsAdults with the lowest quality diet, as measured using the FSAm-NPS dietary index (underpinning the Nutri-Score), and the highest ultra-processed food consumption (NOVA classification) were at the highest risk for all cause and cardiovascular mortality. A significant proportion of the higher mortality risk associated with an elevated intake of nutrient poor foods was explained by a high degree of food processing. In contrast, the relation between a high ultra-processed food intake and mortality was not explained by the poor quality of these foods.
EMAeHealth, a digital tool for the self-management of women’s health needs during pregnancy, childbirth and the puerperium: protocol for a hybrid effectiveness-implementation study
Authors: Espinosa Cifuentes Maite , Artieta-Pinedo Isabel , Paz-Pascual Carmen , Bully-Garay Paola , García-Alvarez Arturo 
Published: September 2022

IntroductionEHealth can help health service users take a more active role in decision-making and help health professionals guide the patient in this process. A digital tool has been designed to support maternal education (ME), and it is organised into four areas: (1) information, (2) communication, (3) health self-management and (4) clinical data. The main objective of the study is to evaluate the effectiveness of the EMAeHealth digital tool, and assess its usability and acceptability under routine conditions.Methods and analysisHybrid implementation-effectiveness design: (1) A cluster randomised, prospective, longitudinal, multicentre clinical trial to evaluate the effectiveness of EMAeHealth in (A) improving health-related quality of life (primary outcome), (B) improving self-efficacy for labour and childbirth and self-efficacy in breast feeding and (C) reducing the number of visits to the obstetric emergency services and health centre in situations of ‘non-pathological pregnancy’, ‘false labour pains’ and ‘non-pathological puerperium’. The EMAeHealth intervention plus usual care will be compared with receiving only usual care, which includes traditional ME. N=1080 participants, 540 for each study arm. Two measurements will be made throughout the pregnancy and three in the first 16 weeks post partum. (2) A mixed-method study to evaluate the usability and acceptability of the tool, barriers and facilitators for its use, and implementation in our health system: focus groups (women, professionals and agents involved) and a quantitative analysis of implementation indicators. Analysis: It will be carried out by intention to treat, using mixed models taking into account the hierarchical structure of the data and per protocol to evaluate the effectiveness of the express use of the digital tool.Ethics and disseminationClinical Research Ethics Committee of Euskadi, Spain, (Ref: PI2020044) approved this study. The results will be actively disseminated through manuscript publications and conference presentations.Trial registration numberNCT04937049.