bluuebunny/crossref_metadata_2025_split huggingface dataset:
A photochemical model of Triton’s atmosphere paired with an uncertainty propagation study
Authors: Benne B. , Dobrijevic M. , Cavalié T. , Loison J.-C. , Hickson K. M. 
Published: September 2022

Context.The largest satellite of Neptune, Triton, is a likely Kuiper Belt object captured by the planet. It has a tenuous nitrogen atmosphere, similar to that of Pluto, and it may be an ocean world. The Neptunian system has only been visited once: by Voyager 2 in 1989. Over the past few years, the demand for a new mission to the ice giants and their systems has risen. Thus, a theoretical basis upon which to prepare for such a mission is needed.Aims.We aim to develop a photochemical model of Triton’s atmosphere with an up-to-date chemical scheme, as previous photochemical models date back to the post-flyby years. This purpose is to achieve a better understanding of the mechanisms governing Triton’s atmospheric chemistry and to highlight the critical parameters that have a significant impact on the atmospheric composition. We also study the model uncertainties to find what chemical studies are necessary to improve the modeling of Triton’s atmosphere.Methods.We used a model of Titan’s atmosphere and tailored it to Triton’s conditions. We first used Titan’s chemical scheme before updating it to better model Triton’s atmospheric conditions. Once the nominal results were obtained, we studied the model uncertainties with a Monte Carlo procedure, considering the reaction rates as random variables. Finally, we performed global sensitivity analyses to identify the reactions responsible for model uncertainties.Results.With the nominal results, we determined the composition of Triton’s atmosphere and studied the production and loss processes for the main atmospheric species. We highlighted key chemical reactions that are most important for the overall chemistry. We also identified some key parameters that have a significant impact on the results. The uncertainties are high for most of the main atmospheric species since the atmospheric temperature is very low. We identified key uncertainty reactions that have the greatest impact on the result uncertainties. These reactions must be studied as a priority in order to improve the significance of our results by finding ways of lowering these uncertainties.
Régulation de la pression artérielle
Authors: Fardol Dicken , Gulmez Aylin , Yoldas Zeynep , Lourdel Stéphane 
Published: September 2022

Le Master de Biologie intégrative et physiologie (BIP) de Sorbonne Université recouvre un large champ disciplinaire, allant de la biologie du vieillissement à la physiopathologie, à la nutrition, aux bioressources marines et aux neurosciences, dont les enjeux sont essentiels aussi bien sur le plan fondamental qu’appliqué.
L’objectif de la mention est de former des spécialistes de haut niveau aux concepts les plus récents de la biologie intégrative. La mention forme les étudiants à appréhender les mécanismes qui sous-tendent les différentes fonctions physiologiques et pathologiques depuis la cellule jusqu’à l’organisme, chez les animaux ou dans l’espèce humaine.
„Shifting the Curve“: Neue Entwicklungen und Herausforderungen im Bereich der Public Mental Health
Authors: Reininghaus Ulrich , Schomerus Georg , Hölling Heike , Seidler Andreas , Gerhardus Ansgar , Gusy Burkhard , Riedel-Heller Steffi 
Published: September 2022

ZusammenfassungIn der nationalen und internationalen Forschung nimmt das noch relativ junge Fach der Public Mental Health einen immer wichtigeren Stellenwert ein. Allerdings bleibt eine zentrale Herausforderung, dieses Fach in seiner Interdisziplinarität abzubilden und den Diskurs im Spannungsfeld von Public Health, psychiatrischer Epidemiologie, psychischer Gesundheitsförderung, Prävention und Versorgungsforschung zu führen, um sein innovatives Potenzial vollständig auszuschöpfen. In diesem Spannungsfeld stellen sich eine Reihe von grundsätzlichen konzeptionellen und methodischen Fragen, die in diesem Essay unter Bezugnahme auf die Populationsstrategie von Geoffrey Rose exemplarisch auch hinsichtlich fundamentaler Ursachen von sozialen und gesundheitlichen Ungleichheiten erörtert und adressiert werden sollen, mit dem letztendlichen Ziel, die Grundlage zur Erfassung und Veränderung von psychischer Gesundheit auf Populationsebene zu verbessern.
Teletherapie – Möglichkeiten der Rehabilitation bei Patient*innen nach Knie-Totalendoprothese
Authors: Ayzikov Dmitry 
Published: September 2022

ZusammenfassungUm den Bedarf an Physiotherapie bei der steigenden Zahl an Patient*innen nach einer endoprothetischen Versorgung auch in Zukunft zu decken, benötigen die Gesundheitsdienstleister*innen eine Lösung für die Bereitstellung einer angemessenen Therapie. Eine mögliche Option könnte die Teletherapie sein, die aufgrund der pandemischen Lage von SARS-COV-2 zunehmend an Bedeutung gewinnt. Teletherapie kann Menschen, die aus diversen Gründen nicht in die Praxis kommen können, eine Therapie ermöglichen, und birgt ein kostensparendes Potenzial.Diese Arbeit sollte klären, ob die physiotherapeutische Teletherapie bei Patient*innen nach einer endprothetischen Versorgung des Knies mit einer konventionellen Physiotherapie vergleichbar ist. Anhand einer Literaturrecherche auf den Datenbanken Cochrane, Europe PMC und PubMed vom 01.01.-04.05.2021 wurden 4 geeignete RCTs gefunden. Alle 4 RCTs zeigten, dass die Teletherapie positive Auswirkungen auf die Funktion der Patient*innen nach einer Knie-Totalendoprothese hat und einer konventionellen Physiotherapie nicht unterlegen ist. Die Ergebnisse waren klinisch signifikant. Die Teletherapie kann demnach als Alternative in Betracht gezogen werden.Allerdings sind manche Studien auf Grund von methodologischen Schwächen kritisch zu betrachten, sodass diese Arbeit keine eindeutige Empfehlung aussprechen kann. Für ein eindeutiges Ergebnis und eine starke klinische Empfehlung bei Patient*innen nach Knie-Totalendoprothese sind weitere Studien nötig.
Regionale Gesundheitsnetzwerke in Deutschland: Charakteristik und
Finanzierung am Beispiel regionaler Demenznetzwerke
Authors: Michalowsky Bernhard , Afi Adel , Holle Bernhard , Thyrian Jochen René , Hoffmann Wolfgang 
Published: September 2022

Zusammenfassung
Ziel der Studie Darstellung der Charakteristik, Finanzierungsstrukturen
und Herausforderungen regionaler Demenznetzwerke sowie der Nutzung der
regionalen finanziellen Netzwerkförderung nach § 45c Abs. 9 SGB
XI.
Methodik Die Analyse basierte auf Daten von 120 Demenznetzwerken, welche
Angaben zur Netzwerkcharakteristik (Verortung, Gründungsjahr, Ziele,
Organisations-, Personal- und Finanzierungsstruktur), den Herausforderungen
sowie der Nutzung der regionalen Netzwerkförderung nach § 45c
Abs. 9 SGB XI machten. Unterschiede in der Organisations-, Personal- und
Finanzierungsstruktur in Abhängigkeit von der Netzwerkcharakteristik
wurden unter der Nutzung von t-Tests und ANOVA analysiert. Die Nutzung der
regionalen Netzwerkförderung nach § 45c Abs. 9 SGB XI wurde
deskriptiv dargestellt und vor dem Hintergrund der geplanten Novellierung
für 2022 diskutiert.
Ergebnisse Der Großteil der Netzwerke etablierte sich zwischen
2011 und 2015, verfolgte Aufklärungs- und Versorgungsziele und vernetzte
im Mittel 28 Akteure. Medizinisch-assoziierte und länger bestehende
Netzwerke sowie Netzwerke mit einer Rechtsform, verfügten über
eine signifikant höhere Anzahl an Netzwerkpartnern und aktiv in die
Netzwerkarbeit eingebundenen Personen sowie Finanzierungsquellen. Die Vernetzung
der Akteure und die Finanzierung wurden als größte
Herausforderungen gesehen. Die regionale Netzwerkförderung nach
§45c Abs. 9 SGB XI war vielen Netzwerken (50%) noch unbekannt.
28% hatten sich bewusst gegen eine Förderung ausgesprochen.
Lediglich jedes zehnte Netzwerk erhielt Fördergelder über den
§45c Abs. 9 SGB XI.
Schlussfolgerung Regionale Demenznetzwerke sind strukturell sehr heterogen
aufgestellt. Die Langlebigkeit, eine medizinische Orientierung sowie eine
bindende Rechtsform können die Anzahl vernetzter Partner sowie
Finanzierungsquellen signifikant beeinflussen und sollten daher
berücksichtigt werden. Bislang konnte nur ein Netzwerk je Landkreis die
maximale Netzwerkförderung nach §45c Abs. 9 (20.000€)
erhalten, was die Nutzbarkeit dieser Förderung, limitiert. Die
gesetztliche Novellierung vergrößert nun die Anzahl an zu
fördernden Netzwerken sowie die Förderhöhe. Es bleibt
abzuwarten, in wie weit diese Anpassungen die Nutzung der regionalen
Netzwerkförderung beeinflusst.
Convenient Synthesis of Ellagic Acid from Methyl Gallate and SARS-CoV-2 3CLpro Antiviral Activity
Authors: Pujol M. Dolors , Navarro Francesc , Hamri Salha , Reches Rosa , Viñas Miquel , Jahani Daniel , Ginard Jaume , Vilardell Josep , Abián Olga 
Published: September 2022

AbstractA practical synthesis of ellagic acid has been achieved from methyl gallate by a proposed synthetic route of five steps, consisting of ketal protection, regioselective bromination, bis-lactonization, C–C bond formation between the aromatic rings of the galloyl groups, and ketal deprotection, in 38% overall yield. Ellagic acid showed a slight inhibitory activity against SARS-CoV-2 3CLpro.
Asymmetric Synthesis of Derivatives of Alanine via Michael Addition Reaction and their Biological Study
Authors: Mkrtchyan Anna F. , Tovmasyan Anna S. , Paloyan Ani M. , Sargsyan Armen S. , Simonyan Hayarpi M. , Sahakyan Lusine Yu. , Petrosyan Satenik Gh. , Hayriyan Liana A. , Sargsyan Tatev H. 
Published: September 2022

AbstractNi(II) complex of the Schiff base of the chiral auxiliary (S)-2-N-(N′-benzylprolyl)aminobenzophenone (BPB) and dehydroalanine as the initial complex in the addition reaction was investigated. The obtained four new derivatives of α-alanine were investigated as inhibitors of aldose reductase. Only one of them: (S)-2-amino-3-[(4-methylbenzyl)amino]propanoic acid showed activity. It becomes a reason for studying the patterns of biological activity of the structure of α-amino acids. The results of docking analysis indicated that (S)-2-amino-3-[(4-methylbenzyl)amino]propanoic acid demonstrated the ability to form bonds with different functional groups of the enzyme which let us assume that some amino acids of nonfunctional groups, such as Trp20 of ALR2, can play a key role in inhibitor–enzyme interactions.
Photo-organocatalytic Synthesis of β-Keto Sulfonyl Fluorides via Radical Fluorosulfonylation of Vinyl Acetates
Authors: Wang Peng , Li Shao-Jie , Liao Saihu , Zhang Honghai , Yang Na 
Published: September 2022

AbstractA metal-free synthesis of useful β-keto sulfonyl fluorides has been established via radical fluorosulfonylation of ketone-derived vinyl acetates under photoredox organocatalysis by using 1-fluorosulfonyl benzoimidazolium (FABI) as the fluorosulfonyl radical source and oxygen-doped anthanthrene (ODA) as the photocatalyst. A series of aryl and alkyl β-keto sulfonyl fluorides as well as cyclic analogues can be readily obtained in moderate to high yields from widely available ketone starting materials.
Venous Thromboembolism and Risk of Cancer in Users of Low-Dose Aspirin: A Danish Population-Based Cohort Study
Authors: Kurt Gencer , Nagy Dávid , Troelsen Frederikke S. , Skajaa Nils , Erichsen Rune , Farkas Dóra K. , Sørensen Henrik T. 
Published: September 2022

Abstract
Background Aspirin may reduce the risk of cancer, particularly gastrointestinal cancer, and venous thromboembolism (VTE). VTE can be the first symptom of occult cancer, but whether it is also a marker of occult cancer in aspirin users remains unknown. Therefore, we investigated the risk of cancer subsequent to VTE among users of low-dose aspirin.
Methods We conducted a population-based cohort study using data from Danish health registries for the years 2001 to 2018. We identified all patients with a first-time diagnosis of VTE who also redeemed a prescription for low-dose aspirin (75–150mg) within 90 days prior to the first-time VTE. We categorized aspirin users by the number of prescriptions filled as new users (<5 prescriptions), short-term users (5–19 prescriptions), and long-term users (>19 prescriptions). We computed the absolute cancer risks and standardized incidence ratios (SIRs) for cancer using national cancer incidence rates.
Results We followed-up 11,759 users of low-dose aspirin with VTE. Long-term users comprised 50% of aspirin users. The 1-year absolute risk of cancer was 6.0% for new users and 6.7% for short-term and long-term users, with corresponding SIRs of 3.3 (95% confidence interval [CI]: 2.8–4.0), 3.2 (95% CI: 2.9–3.7), and 2.8 (95% CI: 2.6–3.2), respectively. After the first year of follow-up, the SIR decreased to 1.2 (95% CI: 1.1–1.4) for new users, 1.1 (95% CI: 1.1–1.3) for short-term users, and 1.1 (95% CI: 1.0–1.2) for long-term users.
Conclusion VTE may be a harbinger of cancer, even in users of low-dose aspirin, regardless of duration of use.
Behaviorally-Oriented Intensive Aphasia Program: Collaboration Leads to Optimal Outcomes
Authors: Fleming Shawna , Clark Brittany 
Published: September 2022

AbstractAphasia is an acquired disorder affecting all language components across modalities. While common therapeutic approaches can result in some improvements, multiple studies establish that intensive therapeutic interventions are most effective; however, these approaches are not well defined. In addition, behaviorally-oriented approaches have been shown to be effective for other conditions, but have not yet been introduced to the treatment of aphasia. The purpose of the current study was to examine the efficacy of a novel, behaviorally-oriented, intensive communication intervention for aphasia (BICA) designed by a speech-language pathologist (second author) and a Board Certified Behavior Analyst (first author) for a 71-year-old woman with post–stroke aphasia. Using a case study design, the participant was provided with 12 hours/week of therapy for 12 weeks focusing on functional communication goals using a behavioral interpretation of language and stimulus control transfer procedures. The behavior analyst determined conceptually systematic interventions based on targets selected by the speech-language pathologist. The participant demonstrated substantial improvements in written language expression and comprehension, reading fluency, oral language expression, naming, and improved quality of life. Given the substantial gains the participant made in oral and written language post-stroke using the BICA therapy, further study is warranted.
Comparison of Outcomes with Triple-Regimen versus Double-Regimen Transarterial Chemoembolization
Authors: Smolock Amanda R. , Deochand Osmani , Rilling William S. , Patel Parag J. , Hohenwalter Eric J. , White Sarah B. , Scheidt Matthew J. 
Published: September 2022

AbstractWe sought to evaluate differences in outcomes between double versus triple transarterial chemoembolization (TACE). TACEs over a 1-year period were retrospectively reviewed and divided into two groups: double and triple. Imaging response and complications were made on a per-procedure basis. Student's t-test was used to calculate differences in continuous variables, and chi-square test was used to calculate differences in categorical values.Overall tumor response was similar between the two groups, and there were no significant differences in complications between groups. Outcomes are similar between double and triple conventional TACE, suggesting that adding a third drug may only contribute to cost.
Geometric and doping effects on radiative recombination in thin-film near-field energy converters
Authors: Feng Dudong , Yee Shannon K. , Zhang Zhuomin M. 
Published: September 2022

Modeling radiative recombination is crucial to the analysis of radiative energy converters. In this work, a local radiative recombination coefficient is defined and derived based on fluctuational electrodynamics that is applicable to thin-film cells in both the near field and far field. The predicted radiative recombination coefficient of an InAs cell deviates from the van Roosbroeck–Shockley relation when the thickness is less than 10 µm, and the difference exceeds fourfold with a 10 nm film. The local radiative recombination coefficient is orders of magnitude higher when an InAs cell is configured in the near field. The local radiative recombination coefficient reduces as the doping level approaches that of a degenerate semiconductor. The maximum output power and efficiency of a thermoradiative cell would be apparently overpredicted if the electroluminescence coefficient defined in this paper were taken as unity for heavily doped semiconductors.
Phosphatidylserine orchestrates Myomerger membrane insertions to drive myoblast fusion
Authors: Gamage Dilani G. , Melikov Kamran , Munoz-Tello Paola , Wherley Tanner J. , Focke Leah C. , Leikina Evgenia , Huffman Elliana , Diao Jiajie , Kojetin Douglas J. , Prasad Vikram , Chernomordik Leonid V. , Millay Douglas P. 
Published: September 2022

Muscle cell fusion is a multistep process where the final step of the reaction drives progression beyond early hemifusion events to complete fusion. This step requires activity of the muscle-specific fusogen Myomerger, a single-pass transmembrane protein containing 84 amino acids with an ectodomain that includes two α-helices. Previous studies have demonstrated that Myomerger acts by destabilizing membranes through generation of elastic stresses in the outer leaflet of the plasma membrane. An obvious question is how such destabilizing activity might be regulated to avoid membrane and cellular damage, and how the two juxtaposed helices cooperate in fusion. Using cellular fusion assays and in vitro liposome assays, we report that the two helices possess unique characteristics, both of which are needed for full activity of the protein. We demonstrate that externalized phosphatidylserine (PS), a lipid previously implicated in myoblast fusion, has a determinant role in the regulation of Myomerger activity. The membrane-proximal, amphipathic Helix-1 is normally disordered and its α-helical structure is induced by PS, making membrane interactions more efficacious. The distal, more hydrophobic Helix-2 is intrinsically ordered, possesses an ability to insert into membranes, and augments the membrane-stressing effects of Helix-1. These data reveal that Myomerger fusogenic activity is an exquisitely orchestrated event involving its two ectodomain helices, which are controlled by membrane lipid composition, providing an explanation as to how its membrane-stressing activity is spatially and temporally regulated during the final step of myoblast fusion.
Quantum annealing with twisted fields
Authors: Imoto Takashi , Seki Yuya , Matsuzaki Yuichiro , Kawabata Shiro 
Published: September 2022

Abstract
Quantum annealing (QA) is a promising method for solving combinational optimization problems and performing quantum chemical calculations. The main sources of errors in QA are the effects of decoherence and non-adiabatic transition. We propose a method for suppressing both these effects using inhomogeneous twist operators corresponding to the twist angles of transverse fields applied to qubits. Furthermore, we adopt variational methods to determine the optimal inhomogeneous twist operator for minimizing the energy of the state after QA. Our approach is useful for increasing the energy gap and/or making the quantum states robust against decoherence during QA. In summary, our results can pave the way to a new approach for realizing practical QA.
Image recognition by FFT, artificial intelligence and k-nearest neighbors approach
Authors: Balabanova I S , Georgiev G I 
Published: September 2022

Abstract
This paper presents procedures of processing and recognition of color images by means of artificial intelligence and computer aided training. Two stages of processing have been applied with regard to extraction of features. Processing involves conversion of RGB images in grayscale and binary; and conversion of RGB, grayscale and binary into index formats. Spectral analysis is also applied in here with Fourier’s algorithm for fast conversion concerning indicated graphic formats and segmentation of the real and imaginary complex parts. Activities related with training, assessment and synthesis of feed-forward neural networks and probabilistic neural networks, based on Accuracy and Mean-Squared Error analysis. Special emphasis is made on a method for computer aided training k-nearest neighbors with Euclidean, Euclidean squared, Cityblock and Chebychev metric distances in relation to Cross-validation accuracy value. Some positive indications have been achieved in recognition of assigned graphic images by means of the employed mathematical apparatus.
Hand-held and UAV camera comparison in building thermal inspection process
Authors: Stokowiec K , Sobura S 
Published: September 2022

Abstract
Thermal building inspections indicate the growing interest among researchers due to the global climate changes resulting in legislations and policy contribution to low-energy consumption. The technologies applied during the experiments involve infrared cameras: both hand-held and on unmanned aerial vehicles. The research conducted in the public building in Kielce included the analysis of glass partition from the inside of the building by means of hand-held and UAV camera. The temperature distributions presented in the graphs proved that both methods are accurate in case of such investigations. However, during the experiments, it was concluded that hand-held camera is far more convenient.
Identification of building environment problems
Authors: Telejko M , Majewski G , Kotrys-Działak D 
Published: September 2022

Abstract
The indoor environment is an enclosed space where people tend to spend more and more time. Its atmosphere has a significant impact on room users. The article deals with the self – reported problems of volunteers related to the sick building syndrome (SBS). The tests were performed in the large lecture room of Kielce University of Technology, where 69 students took part in the questionnaire survey on indoor environment and health related problems. The results show that the students experienced SBS symptoms and that they might have an impact on their concentration during the lecture.
Contributions to an additive method for manufacturing solderless assembly for electronics
Authors: Varzaru G , Savu M , Mihailescu B , Ionescu C , Branzei M 
Published: September 2022

Abstract
The demand for more reliable electronic and affordable products has generated innovative activities in electronic packaging that have highlighted the great benefits of additive technologies. This approach requires new equipment for the electronic assembly line, such as 3D-printer, but especially new materials. Within the additive techniques, one that still keeps the assembly line is the Occam Process. This disruptive concept eliminates the use of solder alloy, and combines into one two technological processes: the manufacture of the printed circuit board and the electronic assembly. Following this concept, the paper presents the result of the research of a couple of electrically conductive adhesive materials and a method for their qualification in the manufacture of solderless electronic modules that can handle ultra high-frequency and microwave signals. A practical solution is to compare the frequency behavior of two identical test structures, one made by the adhesive material, and the other by copper. The comparative analysis showed that electrically conductive adhesives present a slightly better response at high frequencies than copper in terms of insertion loss and return loss in the range 0 to 10 GHz; the adhesive replacement for solder alloy to connect temperature-sensitive
components operating at high frequency is a good alternative.