bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mentioning smoking cessation assistance during healthcare consultations matters: findings from Dutch survey research
Authors: van Westen-Lagerweij Naomi A , Bommelé Jeroen , Willemsen Marc C , Croes Esther A 
Published: August 2022

Abstract

Background
Smoking cessation assistance (SCA) can help smokers to successfully quit smoking. It is unclear to what extent hearing about SCA from a healthcare professional is associated with using SCA during a quit attempt.

Methods
We used pooled survey data from the 2016, 2018 and 2020 ‘Module Substance Use’ survey in the Netherlands (N = 5928). Multivariate logistic regression analyses were used to determine the association between having heard about SCA from one or more healthcare professionals in the last year and the use of SCA during the most recent quit attempt in the last year. We used two models: model 1 included any type of assistance; model 2 included assistance typically recommended by treatment guidelines (i.e. counselling and pharmacotherapy).

Results
Hearing about any type of SCA from a healthcare professional in the last year was significantly associated with using any type of SCA during the most recent quit attempt [odds ratio (OR) = 2.96; 95% confidence interval (CI) 2.16–4.06; P &lt; 0.001]. We found the strongest association between hearing about counselling and/or pharmacotherapy and using counselling and/or pharmacotherapy (OR = 5.40; 95% CI 4.11–11.60; P &lt; 0.001). The odds of using SCA was not significantly higher for smokers who had heard about it from two or more healthcare professionals compared to one healthcare professional (OR = 1.38; 95% CI 0.79–2.42; P = 0.26).

Conclusions
Healthcare professionals can play a greater role in stimulating the use of SCA, especially counselling and pharmacotherapy, by mentioning it to smokers during consultations.
Bacterial community composition and indicators of water quality in Caizi Lake, a typical Yangtze-connected freshwater lake
Authors: Gao Na , Liang Yangyang , Li Jing , Cui Kai , Lu Wenxuan 
Published: August 2022

Abstract
Caizi Lake is an important lake connected to the Yangtze River in Anhui Province and a crucial connection for the Yangtze-to-Huaihe Water Diversion Project. There were marked differences in trophic status of the six sampling sites based on the physicochemical characterization. The Bacterial Eutrophic Index (BEI), used to quantify water quality, was well related to Carlson's trophic state index (TSI) (Spearman's ρ = 0.829, P &lt; 0.05). Mean TSI and BEI were 54 and 0.58, respectively, indicating that Caizi Lake was slightly eutrophic. Actinobacteriota were the predominant bacterial phylum in the water and Acidobacteriota in sediments. The diversity and composition of the bacterial community was markedly different between sites for water but not sediment samples. Unlike other Yangtze-connected freshwater lakes, the distance-based redundancy analysis revealed that dissolved oxygen affected the composition of the planktonic bacterial community (P &lt; 0.001), while total phosphorus was the major factor in the sediments (P &lt; 0.05). The water quality of Caizi Lake has significantly improved since a few years ago. These results contribute to the long-term monitoring of the ecological quality of the water environment along the Yangtze River to the Huaihe River.
Plasma Membrane Ca2+ ATPase Activity Enables Sustained Store-operated Ca2+ Entry in the Absence of a Bulk Cytosolic Ca2+ Rise
Authors: Barak Pradeep , Kaur Suneet , Scappini Erica , Tucker Charles J , Parekh Anant B 
Published: August 2022

Abstract
In many cell types, the rise in cytosolic Ca2+ due to opening of Ca2+ release-activated Ca2+ (CRAC) channels drives a plethora of responses, including secretion, motility, energy production, and gene expression. The amplitude and time course of the cytosolic Ca2+ rise is shaped by the rates of Ca2+ entry into and removal from the cytosol. However, an extended bulk Ca2+ rise is toxic to cells. Here, we show that the plasma membrane Ca2+ ATPase (PMCA) pump plays a major role in preventing a prolonged cytosolic Ca2+ signal following CRAC channel activation. Ca2+ entry through CRAC channels leads to a sustained sub-plasmalemmal Ca2+ rise but bulk Ca2+ is kept low by the activity of PMCA4b. Despite the low cytosolic Ca2+, membrane permeability to Ca2+ is still elevated and Ca2+ continues to enter through CRAC channels. Ca2+-dependent NFAT activation, driven by Ca2+ nanodomains near the open channels, is maintained despite the return of bulk Ca2+ to near pre-stimulation levels. Our data reveal a central role for PMCA4b in determining the pattern of a functional Ca2+ signal and in sharpening local Ca2+ gradients near CRAC channels, whilst protecting cells from a toxic Ca2+ overload.
Abdominal Aortic Calcification, Bone Mineral Density, and Fractures: A Systematic Review and Meta-analysis of Observational Studies
Authors: Gebre Abadi K , Lewis Joshua R , Leow Kevin , Szulc Pawel , Scott David , Ebeling Peter R , Sim Marc , Wong Germaine , Lim Wai H , Schousboe John T , Kiel Douglas P , Prince Richard L , Rodríguez Alexander J 
Published: August 2022

Abstract

Background
Abdominal aortic calcification (AAC) has been inconsistently associated with skeletal health. We aimed to investigate the association of AAC with bone mineral density (BMD) and fracture risk by pooling the findings of observational studies.

Methods
MEDLINE, EMBASE, Web of Science, and Google Scholar were searched (August 2021). All clinical studies that assessed the association between AAC and BMD or fracture were included. AAC was categorized into any/advanced (all higher reported groups) versus no/less advanced (lowest reported group). Pooled standardized mean differences (SMDs) and risk ratios (RRs) with 95% confidence intervals (CI) were determined for BMD and fracture, respectively, using random-effects models.

Results
Of 2 192 articles screened, 86 (61 553 participants) were included in the review, while 42 provided data for meta-analysis. AAC was associated with lower BMD at the total hip (SMD = −1.05 [95%CI: −1.47 to −0.63]; 16 studies), femoral neck (−0.25 [−0.46 to−0.04]; 10), and lumbar spine (−0.67 [−1.21 to −0.12]; 20). AAC was associated with a greater risk of any fracture (RR = 1.73 [95%CI: 1.48–2.02]; 27). AAC was also associated with vertebral, non-vertebral, and hip fractures. In dose–response analysis, the highest AAC group had greater risks of any, vertebral and non-vertebral fractures.

Conclusions
AAC is associated with lower BMD and increased fracture risk at multiple sites, underscoring the potential importance of vascular disease on skeletal health. Detection of AAC at the time of BMD testing may provide clinicians with prognostic information about bone health to enhance osteoporosis screening programs and fracture risk prediction.
Factors Associated With Health Care Delays Among Adults Over 50 During the COVID-19 Pandemic
Authors: Chan Athena C Y , Sneed Rodlescia S 
Published: August 2022

AbstractBackgroundAdults over 50 have high health care needs but also face high coronavirus disease 2019 (COVID-19)-related vulnerability. This may result in a reluctance to enter public spaces, including health care settings. Here, we examined factors associated with health care delays among adults over 50 early in the COVID-19 pandemic.MethodsUsing data from the 2020 wave of the Health and Retirement Study (N = 7 615), we evaluated how race/ethnicity, age, geographic region, and pandemic-related factors were associated with health care delays.ResultsIn our sample, 3 in 10 participants who were interviewed from March 2020 to June 2021 reported delays in medical or dental care in the early stages of the COVID-19 pandemic. Non-Hispanic Whites (odds ratio [OR]: 1.37; 95% confidence interval [CI]: 1.19–1.58) and those of other racial/ethnic backgrounds (OR: 1.31; 95% CI: 1.02–1.67) delayed care more than Non-Hispanic Blacks. Other factors associated with delayed care included younger age, living in the Midwest or West, knowing someone diagnosed with or who died from COVID-19, and having high COVID-19-related concerns. There were no differences in care delays among adults aged &gt; 70; however, among those ≤ 70, those who knew someone diagnosed with COVID-19 were more likely to delay care than those who did not. Additionally, among those ≤ 70, Non-Hispanic Whites and those of other racial/ethnic backgrounds delayed care more than Non-Hispanic Blacks and Hispanics.ConclusionsThere is considerable heterogeneity in care delays among older adults based on age, race/ethnicity, and pandemic-related factors. As the pandemic continues, future studies should examine whether these patterns persist.
Test of P-wave receiver functions for a seismic velocity and gravity model across the Baikal Rift Zone
Authors: Zhou Zhipeng , Thybo Hans , Tang Chi-Chia , Artemieva Irina , Kusky Timothy 
Published: August 2022

SUMMARY
The seismic receiver function (RF) technique is widely used as an economic method to image earth's deep interior in a large number of seismic experiments. P-wave receiver functions (RFs) constrain crustal thickness and average Vp/Vs in the crust by analysis of the Ps phase and multiples (reflected/converted waves) from the Moho. Regional studies often show significant differences between the Moho depth constrained by RF and by reflection/refraction methods. We compare the results from RF and controlled source seismology for the Baikal Rift Zone by calculating 1480 synthetic RFs for a seismic refraction/reflection velocity model and processing them with two common RF techniques [H–κ and Common Conversion Point (CCP) stacking]. We compare the resulting synthetic RF structure with the velocity model, a density model (derived from gravity and the velocity model), and with observed RFs. Our results demonstrate that the use of different frequency filters, the presence of complex phases from sediments and gradual changes in the properties of crustal layers can lead to erroneous interpretation of RFs and incorrect geological interpretations. We suggest that the interpretation of RFs should be combined with other geophysical methods, in particular in complex tectonic regions and that the long-wavelength Bouguer gravity anomaly signal may provide effective calibration for the determination of the correct Moho depth from RF results. We propose and validate a new automated, efficient method for this calibration.
Upper crustal structure beneath the Qin-Hang and Wuyishan metallogenic belts in Southeast China as revealed by a joint active and passive seismic experiment
Authors: Zheng Mengjie , Xu Tao , Lü Qingtian , Lin Jiyan , Huang Minfu , Bai Zhiming , Deng Yangfan , Zhang Yongqian , Badal José 
Published: August 2022

SUMMARY
Southeast China is one of the most important polymetallic metallogenic provinces in the world. However, distinct differences in the type and origin of the mineral deposits are present between the major metallogenic belts in this province. To deepen our knowledge of this regional metallogenic setting, investigate the factors controlling its metallogenic differences and explore the feasibility of active and passive seismic imaging, we performed a multibatch seismic experiment using active and passive sources with the help of 437 short-period seismographs deployed across the Qin-Hang and Wuyishan metallogenic belts in Southeast China. We resolved the S-wave velocity structure beneath the profile using ambient noise tomography and derived a Vp/Vs model by combining with a published P-wave model. A good correlation between the obtained seismic velocity models and geological observations is observed. The Proterozoic volcanic-sedimentary rock series and the Fuzhou-Yongfeng sedimentary basin are identified by low P- and S-wave velocities, high Vp/Vs ratios and low S-wave velocity perturbations. Within the core of the Wuyishan Metallogenic Belt, several narrow, elongated and low seismic velocity anomalies are considered to be signs of the nearby fault zones, and these anomalies provide reference information on the extension and pattern of these faults at depth. Combined with the geological and mineralogical evidence, we propose that theses faults function as ore-guiding structures and facilitate the formation of regionally representative mineral species and metal assemblages.
Failure of diet-induced transcriptional adaptations in alpha-synuclein transgenic mice
Authors: Kilzheimer Alexander , Hentrich Thomas , Rotermund Carola , Kahle Philipp J , Schulze-Hentrich Julia M 
Published: August 2022

Abstract
Nutritional influences have been discussed as potential modulators of Parkinson’s disease (PD) pathology through various epidemiological and physiological studies. In animal models, a high-fat diet (HFD) with greater intake of lipid-derived calories leads to accelerated disease onset and progression. The underlying molecular mechanisms of HFD-induced aggravated pathology, however, remain largely unclear. In this study, we aimed to further illuminate the effects of a fat-enriched diet in PD by examining the brainstem and hippocampal transcriptome of alpha-synuclein transgenic mice exposed to a life-long HFD. Investigating individual transcript isoforms, differential gene expression and co-expression clusters, we observed that transcriptional differences between wild-type (WT) and transgenic animals intensified in both regions under HFD. Both brainstem and hippocampus displayed strikingly similar transcriptomic perturbation patterns. Interestingly, expression differences resulted mainly from responses in WT animals to HFD, while these genes remained largely unchanged or were even slightly oppositely regulated by diet in transgenic animals. Genes and co-expressed gene groups exhibiting this dysregulation were linked to metabolic and mitochondrial pathways. Our findings propose the failure of metabolic adaptions as the potential explanation for accelerated disease unfolding under exposure to HFD. From the identified clusters of co-expressed genes, several candidates lend themselves to further functional investigations.
Burden Predictors for Informal Caregivers of Older Adults in Spain: The Role of Cohabitation, Coping Strategies, Social Support, and Evaluation of Preexisting Relationships
Authors: Montañés Pilar , Lacalle María , Carbonero Domingo , Manzano-García Guadalupe 
Published: August 2022

Abstract
Given the role that informal caregivers play in caring for older adults and the importance of understanding the variables that may predict the burden that they experience due to caregiving, the aim of this article is to examine the relationship between different variables and the caregiver’s subjective burden. Authors examined the relationship between caregivers’ sociodemographic characteristics (age and gender), the context in which the care is provided (cohabiting or not), duty as a reason for taking on the role of caregiver, the evaluation of the preexisting relationship between caregiver and care recipient, as well as coping strategies and social support as predictor variables of subjective burden. For this purpose, 161 caregivers of older Spanish adults completed a questionnaire containing information on the corresponding variables. The results indicate that people cohabiting with care recipients experience a greater subjective burden than those who live apart. The caregiver’s evaluation of their preexisting relationship with the care recipient and perceived family support negatively predicts the subjective burden, while maladaptive coping strategies positively predict it. These results underline the importance of considering these variables in caregiver support programs.
Racial Capitalism: What’s in a Name?
Authors: Hall Catherine 
Published: August 2022

Abstract
Racial capitalism is a way of talking about the intersections of racisms and capitalisms: but how does it operate in practice? This essay explores the derivation of the term and focuses on one concrete example from the eighteenth-century Atlantic. Hereditary racial slavery and mercantile capitalism were articulated together: the expropriation of African lives and labour enabled the production of wealth for slave-owners and merchants. Both the metropolitan state and the Jamaican colonial state were critical in providing economic, legal, political and military frameworks legitimating White power and Black subjection.
The Long Shadows of Gwangju: Transitional Criminal Justice in South Korea
Authors: Vormbaum Moritz 
Published: August 2022

ABSTRACT∞
On 23 November 2021, the former South Korean president, Chun Doo-hwan, died at his home in Seoul less than a month after his successor Roh Tae-woo. Both men were leading figures during a dark period of the country’s military dictatorships. The most egregious example of their authoritarian rule was the killing of hundreds of students and other persons who were protesting against the martial law government in Gwangju in 1980. On the occasion of the deaths of the two former presidents, this article offers an analysis of the events in Gwangju in the context of South Korea’s contemporary history, before examining the criminal justice responses in the 1990s and more recently. In doing so, it presents and analyses the changing role of criminal law in extended periods of transitional justice.
Positive observers for semilinear positive systems
Authors: Binid Abdellaziz , Elarbi Achhab Mohammed , Laabissi Mohamed 
Published: August 2022

Abstract
The problem of designing a positive Luenberger observer for a class of infinite-dimensional semilinear positive systems is addressed. The proposed observer is positive. That is, it ensures that the state estimates are non-negative at any time. The positive observer is designed based on positive bounded perturbation results. In particular it is shown that, under suitable conditions the state estimation error converges exponentially to zero. The results are illustrated by numerical simulations based on an exothermic Plug-Flow Tubular reactor model and show the effectiveness of the proposed positive observer.
A sub-sampled tensor method for nonconvex optimization
Authors: Lucchi Aurelien , Kohler Jonas 
Published: August 2022

Abstract
A significant theoretical advantage of high-order optimization methods is their superior convergence guarantees. For instance, third-order regularized methods reach an $(\epsilon _1,\epsilon _2,\epsilon _3)$third-order critical point in at most ${\mathcal {O}} (\max (\epsilon _1^{-4/3}, \epsilon _2^{-2}, \epsilon _3^{-4} ) )$ iterations. However, the cost of computing high-order derivatives is prohibitively expensive in real applications, including for instance many real-world machine learning tasks. In order to address this problem, we present a sub-sampled optimization method that uses a third-order regularized model to find local minima of smooth and potentially nonconvex objective functions with a finite-sum structure. This algorithm uses sub-sampled derivatives instead of exact quantities and is guaranteed to converge to a third-order critical point. Our analysis relies on a novel tensor concentration inequality for sums of tensors of any order that makes explicit use of the finite-sum structure of the objective function.
On Continuity of Local Epsilon Factors of ℓ-adic Sheaves
Authors: Takeuchi Daichi 
Published: August 2022

Abstract
Let $S$ be a noetherian scheme and $ Y\to S$ be a smooth morphism of relative dimension $1$. For a locally constant sheaf on the complement of a divisor in $Y$ flat over $S$, Deligne and Laumon proved that the universal local acyclicity is equivalent to the local constancy of Swan conductors. In this article, assuming the universal local acyclicity, we show an analogous result of continuity of local epsilon factors. We also give a generalization of this result to a family of isolated singularities.
Double Multiplicative Poisson Vertex Algebras
Authors: Fairon Maxime , Valeri Daniele 
Published: August 2022

Abstract
We develop the theory of double multiplicative Poisson vertex algebras. These structures, defined at the level of associative algebras, are shown to be such that they induce a classical structure of multiplicative Poisson vertex algebra on the corresponding representation spaces. Moreover, we prove that they are in one-to-one correspondence with local lattice double Poisson algebras, a new important class among Van den Bergh’s double Poisson algebras. We derive several classification results, and we exhibit their relation to non-abelian integrable differential-difference equations. A rigorous definition of double multiplicative Poisson vertex algebras in the non-local and rational cases is also provided.
Prevention and Control of Nosocomial Varicella During the United States Varicella Vaccination Program Era
Authors: Drees Marci , Weber David J 
Published: August 2022

Abstract
The United States varicella vaccination program has successfully reduced varicella incidence and hospitalizations by ≥90%, consequently reducing the risk of nosocomial exposures. However, patients and healthcare personnel (HCP) continue to introduce varicella zoster virus (VZV) into healthcare settings. Herpes zoster (HZ) is less contagious than varicella, but it can also result in exposures. Unrecognized varicella and HZ may lead to extensive contact investigations, control efforts, and HCP furloughs that result in significant disruption of healthcare activities as well as substantial costs. Robust occupational health and infection prevention programs that ensure healthcare personnel immunity and prompt recognition and isolation of patients with varicella or HZ will lower the risk of VZV transmission and reduce or eliminate the need to furlough exposed HCP and associated costs.
Adapting Codesign Techniques for the Construction of a Learning Environment of a Written Second Language for the D/deaf
Authors: Paim Polianna , Prietch Soraia Silva , Sánchez J Alfredo 
Published: August 2022

Abstract
In Brazil, many D/deaf persons use the country’s official sign language, Libras, to communicate and develop a sociocultural identity. For most Libras users, learning how to read and write in Portuguese, the country’s official written language, is a challenge. To address the problem, we present a framework for codesigning accessible technologies for and with D/deaf persons. In this paper, we describe and analyze the case study of an environment to support the teaching–learning process of written Portuguese as a second language. Our main contribution is the documented experiences of codesigning with D/deaf and hearing participants, through individual and collaborative work, which increased confidence and creativity and enhanced empathy through sharing own experiences. Various types of participants were included through the entire framework process, and important values were reinforced, such as ownership and self-determination.