bluuebunny/crossref_metadata_2025_split huggingface dataset:
Longitudinal use of patient reported outcomes in pediatric leukemia and lymphoma reveals clinically relevant symptomatic adverse events
Authors: Jacobs Shana S. , Withycombe Janice S. , Castellino Sharon M. , Lin Li , Mack Jennifer W. , McFatrich Molly , Baker Justin N , Freyer David R. , Maurer Scott H. , Mowbray Catriona , Hinds Pamela S. , Reeve Bryce B. 
Published: September 2022

AbstractBackgroundLeukemia and lymphoma (LL) are the most common cancer diagnoses of childhood with high survival rates, but not without impact on the child's functioning and quality of life. This study aimed to use patient‐reported data to describe the symptomatic adverse event (AE) experiences among children with LL diagnoses.MethodsTwo hundred and fifty seven children and adolescents aged 7–18 years with a first LL diagnosis completed the Pediatric Patient‐Reported version of the Common Terminology Criteria for Adverse Events (Ped‐PRO‐CTCAE) and Patient‐Reported Outcome Measurement Information System (PROMIS) Pediatric measures before starting a treatment course (T1) and after the treatment (T2).ResultsFatigue was the most severe AE (68.1% at T1; 67% at T2) and caused the most interference over time. Gastrointestinal AEs were also quite common (e.g., nausea 46.3% at T1 and 48.9% at T2; abdominal pain 42.4% at T1; 46.5% at T2). In general, symptoms were present both at T1 and T2 and did not change significantly in severity or interference. The prevalence of AEs varied by LL disease group (e.g., nausea was most common in acute lymphoblastic leukemia (ALL), fatigue was most severe in ALL and Hodgkin Lymphoma (HL), acute myeloid leukemia had the fewest AEs).ConclusionDespite current supportive care regimens, many children with LL continue to report fatigue, pain, insomnia, and gastrointestinal symptoms as the most frequent or severe symptoms during therapy.
A comprehensive review on phenol‐formaldehyde resin‐based composites and foams
Authors: Ravindran Lakshmipriya , M. S. Sreekala , Kumar S. Anil , Thomas Sabu 
Published: September 2022

AbstractThis article covers the introduction to polymer composites, phenol formaldehyde resin, phenol formaldehyde composites, and foams along with their properties and applications. The previous research in the fields of phenol formaldehyde composites, nanocomposites, and PF foams is also covered in depth. Various combinations of nanomaterials and processes have been investigated in the field of structural composites to meet the requirements of industries such as automotive, aerospace, military, civil, and construction. Due to their different features and possibilities when compared to equivalents composed of other polymers, particularly thermosets, phenol‐formaldehyde reinforced composites are commonly used for large load bearing structural applications. Composite properties can be improved by using nanoparticles, which are materials that have been developed as a result of advances in nanotechnology. This research focuses on a literature review of nanofillers' use to improve the structural properties of phenol‐formaldehyde composites and foams published in the last two decades. The use of nanomaterials to modify composites is examined in depth.
Mechanical and thermal properties of poly (butylene adipate‐butylene terephthalate) modified with phenol hydroxyl terminated polysiloxane
Authors: Yin Shuang , Chen PeiJia , Zhang ZhiCong , Liang WeiJie , Ge Xin , Yu WeiYue , Liu HongJi , Ge JianFang 
Published: September 2022

AbstractThe trend to replace traditional non‐biodegradable plastics with fully biodegradable plastics is the long‐term solution for mitigating the environmental impact of persistent plastic pollution. Poly(butylene adipate‐co‐butylene terephthalate) (PBAT) becomes highly desirable due to its similar physical property to low‐density polyethylene and 100% biodegradability. To enhance the property of PBAT for practical usage, various additives are needed, which are often environmentally unfriendly. In this work, chemically reactive biophenolic polysiloxanes are synthesized through the hydrosilylation addition between the hydrogen‐terminated polysiloxane and the benign product eugenol, catalyzed by the non‐homogeneous platinum. The obtained phenol hydroxyl terminated polysiloxane (PHTP) is used for modified PBAT. By adding 1 wt% of PHTP, the maximum elongation at breakage of 1335.0% is achieved with the improved crystallinity of the composites by 24.2% due to the uniformly PHTP in the PBAT matrix blend. Their morphology, corresponding mechanical properties (tensile and fracture strain), and thermal stability are evaluated as a function of PHTP content. More important, an appropriate amount of PHTP plays an important role in the nucleation centers in the PBAT matrix, confirmed by the positive correlation between the PBAT crystallinity and the amount of PHTP added. A strategy for improving the performance of PBAT‐based environmentally friendly materials is provided within our work.
Fabrication of air‐conditioning tussah silk with capric–stearic eutectic mixture for effective energy storage and thermal‐regulatory applications
Authors: Wang Wei , Zhang Qiyue , Liu Leigen , Sun Yinyin , Wu Jianbing , Tao Jin , Lu Xin 
Published: September 2022

AbstractUnder the urgent demand of effective energy‐storage and thermal‐regulatory textile fabrics, the air‐conditioning tussah silk as a new arrival is endowed with this excellent property by coupling with the phase change material of capric acid–stearic acid eutectic mixture. In addition, the facile pad‐dry‐cure technique used with the assistance of ultrasonic waves efficiently avoided the problems of the sophisticated process and low efficiency in traditional post‐finishing methods with phase change microcapsules. With optimal preparation conditions, the resultant tussah silk exhibited a superior thermal reliability and thermoregulatory character along with a phase enthalpy of 31.80 J g−1 at a phase change temperature of 24.01 °C. Meanwhile, the tested air permeability, mechanical properties and washing fastness showed its favorable thermal and wear comfort. Benefitting from these admirable merits, this air‐conditioning tussah silk with tunable heat storage and release performance could automatically respond to external temperature stimuli, finally contributing to practical application in intelligent protective garments. The intelligent bidirectional temperature‐adjusting property corresponding to the efficient management of human skin temperature is beneficial for constructing a comfortable microclimate for the human body. In brief, our study provides a novel heat‐storage and temperature‐regulating textile with tussah silk as well as unique natural advantages by means of a simple preparation method. © 2022 Society of Industrial Chemistry.
Synthesis of castor oil‐based polyols applicable in acrylated polyurethane coating with improved mechanical properties
Authors: Mohanty Debasmita , Mohanty Smita , Kanny Krishnan 
Published: September 2022

AbstractThe study focuses on the synthesis of polyurethane (PU)‐based coating from modified castor oil (CO) via an in situ polymerization process. CO was modified by employing multiple process steps, that included epoxidation, followed by transesterification and acrylation to get the required polyol for PU synthesis. The structural properties were studied using Fourier transform infrared and 1H NMR spectra. Thermogravimetric analysis (TGA) and differential scanning calorimetry revealed an increase in the final degradation temperature and glass transition temperature from 358 and −46.58 °C to 368 and −37.43 °C respectively after transesterification followed by acrylation of epoxidized CO. Hydroxyl value, acid value, amine value and viscosity were observed to change from 208 mg/KOH, 1.75, 13.09 and 428 mPa s to 233 mg/KOH, 1.16, 19.53 and 318 mPa s after transesterification and acrylation of epoxidized CO. Paint formulations at variable OH:NCO ratios like 1:0.9, 1:1 and 1:1.1 were optimized by following the cross‐cut tape test, lap‐shear test, abrasion resistance test and pencil hardness test. Crosslinking density of the paint samples was calculated and the morphological properties of the optimized coating sample were studied using a scanning electron microscope. TGA was carried out to study the thermal properties of the coating. © 2022 Society of Chemical Industry.
The effectiveness of exercise with behavior change techniques in people with knee osteoarthritis: A systematic review with meta‐analysis
Authors: Ariie Takashi , Takasaki Hiroshi , Okoba Ryota , Chiba Hiroki , Handa Yusuke , Miki Takahiro , Taito Shunsuke , Tsutsumi Yusuke , Morita Masaharu 
Published: September 2022

AbstractObjectiveThe purpose of this systematic review with meta‐analysis was to examine the effectiveness of exercise with behavior change techniques (BCTs) on core outcome sets in people with knee osteoarthritis.Literature SurveyWe searched randomized controlled trials (RCTs) in eight databases (MEDLINE, Embase, CENTRAL, CINAHL, PsycINFO, PEDro, ICTRP, and ClinicalTrials.gov) up to November 4, 2021.MethodologyEligible participants were people with knee osteoarthritis. The intervention was exercise with BCTs. Primary outcomes included physical function, quality of life (QOL) 6 to 12 months after intervention, and adverse events. Secondary outcomes were knee pain, exercise adherence, mobility, and self‐efficacy 3 months or more after intervention. The bias risk was assessed using the Risk of Bias 2 tool. The random‐effects model was used for the meta‐analysis.SynthesisWe found 16 individual BCTs, and 37.7% of trials used a single BCT. For meta‐analysis, we included 21 RCTs (n = 1623). Most outcomes had a very low certainty of evidence, and the risk of bias was the consistent reason for downgrading evidence levels. The standardized mean difference (SMD) with 95% confidence interval (95% CI) was 0.00 (−0.24, 0.24) in physical function, 0.33 (−0.51, 1.17) in exercise adherence, and 0.04 (−0.39, 0.47) in self‐efficacy. The risk ratio (95% CI) of adverse events was 3.6 (0.79, 16.45). QOL was not pooled due to insufficient data (very low certainty of evidence). In contrast, the SMD (95% CI) for knee pain reduction and mobility improvement was −0.33 (−0.53, −0.13) and 0.21 (−0.05, 0.47) with moderate and low certainty of evidence, respectively.ConclusionThe evidence is inconclusive regarding the effectiveness of BCTs with exercises on core outcome sets. Further research should explore the effectiveness of BCTs with valid design.Protocol RegistrationPROSPERO (CRD42020212904).
Computational study of novel pentacene derivatives: Prediction of structural, electronic, and optical properties
Authors: Petralia Salvatore , Forte Giuseppe 
Published: September 2022

AbstractSeveral properties of a series of novel disubstituted pentacenes, in which the substituents are donor and acceptor groups, were investigated by using the ab initio methods. In particular, the role of different substitution positions for acceptor group was explored. Calculations predict that pentacene derivatives were highly soluble and oxidatively stable than the unsubstituted pentacene. Simulated absorption spectra show that 9‐nitropentacen‐2‐amine (PD2) exhibits three absorption bands in the ultraviolet and visible regions. In general, substituents have important impact on the first hyperpolarizability value, and a remarkable enhancement of static second hyperpolarizability is revealed in this study; however, further investigations are required to confirm this finding. Molecular dynamics simulations of the solid state suggest that a material based on 9‐nitropentacen‐2‐amine and 10‐nitropentacen‐2‐amine could exhibit low resistivity due to the potential amount of π–π stacking. The results emphasize the potential of using the herein studied pentacene‐based compounds, with particular reference to PD2, for future applications in the optoelectronic and photonic fields.
Crystal structure of a type III Rubisco in complex with its product 3‐phosphoglycerate
Authors: Huang Qingqiu , Szebenyi Doletha M. E. 
Published: September 2022

AbstractThe crystal structure of the complex of ribulose‐1,5‐bisphosphate carboxylase/oxygenase (Rubisco; EC 4.1.1.39) from Archaeoglobus fulgidus (afRubisco) with its products 3PGAs has been determined to a resolution of 1.7 Å and is of the closed form. Type III Rubiscos such as afRubisco have 18 out of the 19 essential amino acid residues of canonical Rubisco; the 19th is Tyr rather than Phe. Superposition with the structure of a complex of the similar tkRubisco with the six‐carbon intermediate analog 2CABP shows the same conformation of the 19 residues except for Glu46 and Thr51. Glu46 adopts a unique conformation different from that in other Rubiscos and makes two H‐bonds with the ligand 3PGA. Similar to other closed state Rubiscos, the backbone of Thr51 is rotated and the side chain makes an H‐bond with the ligand 3PGA. Two product 3PGA molecules are bound at the active site, overlapping well with the 2CABP of tkRubisco/2CABP. The positions of the P1 and P2 phosphate groups differ by 0.4 and 0.53 Å, respectively, between 2CABP and the two 3PGAs. This afRubisco/3PGA complex mimics an intermediate stage of the carboxylation reaction which occurs after the production of the two 3PGA products but before the reopening of the active site. The stability of this complex suggests that the Rubisco active site will not reopen before both 3PGA products are formed.
Predicting the invasion risk of rugose spiraling whitefly, Aleurodicus rugioperculatus, in India based on CMIP6 projections by MaxEnt
Authors: Maruthadurai Ramasamy , Das Bappa , Ramesh Raman 
Published: September 2022

AbstractBACKGROUNDRugose spiraling whitefly (RSW), Aleurodicus rugioperculatus Martin, is a highly polyphagous invasive pest native to Central America. The occurrence of A. rugioperculatus in the Oriental region was first reported from Pollachi, Tamil Nadu, India in 2017. This pest is widely distributed in India, causing severe economic damage to coconut and other horticultural crops. It is a recent invasion in India and information on its potential distribution is lacking. Thus, in the present study we used the latest Coupled Model Intercomparison Project phase 6 (CMIP6) dataset through Maximum Entropy species distribution modelling (version 3.4.1, MaxEnt) to determine the potential distribution of RSW in present and future climate change scenarios in 2050 and 2070 under Shared Socioeconomic Pathway (SSP) 126 and SSP585 emission scenarios. The performance of the model was evaluated using the area under the curve (AUC), true skill statistics (TSS) and the continuous Boyce index (CBI).RESULTSThe MaxEnt model performed well and predicted the potential distribution of A. rugioperculatus with high‐accuracy AUC values of 0.991 and 0.989, TSS values of 0.891 and 0.842, and CBI values of 0.972 and 0.934 for training and testing, respectively. Jackknife analysis revealed that A. rugioperculatus distribution was mostly influenced by temperature‐based bioclimatic variables contributing 62.1% of the suitability, with precipitation variables contributing the remainder. The most important bioclimatic variables for RSW distribution were annual mean temperature (Bio 1, 28.9%) followed by mean diurnal range (Bio 2, 19.5%) and annual precipitation (Bio 12, 19.1). Potential suitable areas for RSW establishment were mostly found in all coastal and southern states of India. A. rugioperculatus prefers a warm and humid climate, indicating that the tropics, subtropics and temperate regions are ideal for its spread and invasion. Our results highlighted that the suitable habitat area for A. rugioperculatus is predicted to increase and highest probability of invasion and spread in 2050 and 2070 under future climate change scenarios of SSP126 and SSP585 compared to present climatic conditions.CONCLUSIONSThis is the first study to use the latest CMIP6 models and it predicts the potential distribution of RSW in India under present and future climate change scenarios. The implementation of strict domestic quarantine measures may prevent the spread and damage of RSW to noncoastal regions of India. The results of the current study should help in timely monitoring and surveillance of RSW and to formulate integrated pest management strategies at the national level to restrict its spread, invasion and damage to new areas. © 2022 Society of Chemical Industry.
Wolbachia manipulates reproduction of spider mites by influencing herbivore salivary proteins
Authors: Bing Xiao‐Li , Xia Cai‐Bei , Ye Qing‐Tong , Gong Xue , Cui Jia‐Rong , Peng Chang‐Wu , Hong Xiao‐Yue 
Published: September 2022

AbstractBACKGROUNDThe endosymbiont Wolbachia is known for manipulating host reproduction. Wolbachia also can affect host fitness by mediating interactions between plant and herbivores. However, it remains unclear whether saliva proteins are involved in this process.RESULTSWe found that Wolbachia infection decreased the number of deposited eggs but increased the egg hatching rate in the spider mite Tetranychus urticae Koch (Acari: Tetranychidae), a cosmopolitan pest that infects >1000 species of plants. Transcriptomic and proteomic analyses revealed that Wolbachia‐infected mites upregulated the gene expression levels of many T. urticae salivary proteins including a cluster of Tetranychidae‐specific, functionally uncharacterized SHOT1s (secreted host‐responsive proteins of Tetranychidae). The SHOT1 genes were expressed more in the feeding stages (nymphs and adults) of mites than in eggs and highly enriched in the proterosomas. RNA interference experiments showed that knockdown of SHOT1s significantly decreased Wolbachia density, increased the number of deposited eggs and decreased the egg hatching rate.CONCLUSIONTogether, these results indicate that SHOT1s are positively correlated with Wolbachia density and account for Wolbachia‐mediated phenotypes. Our results provide new evidence that herbivore salivary proteins are related to Wolbachia‐mediated manipulations of host performance on plants. © 2022 Society of Chemical Industry.
Hydrological characterization of hydropeaks in mountain rivers (examples from Southern Pyrenees)
Authors: Tena Alvaro , Ville Fanny , Reñe Armengol , Yarnell Sarah M. , Batalla Ramon J. , Vericat Damián 
Published: September 2022

AbstractStreamflow in the Ésera and Upper Cinca Rivers (South Central Pyrenees) experiences alterations in the form of rapid pulses, commonly referred to as hydropeaks, associated with highly variable on‐demand hydropower production from flowing or stored water. A hydrological characterization of the hydropeaks in these two rivers was carried out to examine their distinct hydropeaking pattern during hydrologically contrasted years. The Ésera demonstrated a hydropeaking regime characterized by a high frequency and magnitude, while the Upper Cinca presented a regime with higher frequency but of lesser magnitude. Additionally, this study classified hydropeaks following the shapes proposed in previous studies and assessed their temporal distribution (frequency), timing, and magnitude. Results indicated that hydropeaks were different in shape and magnitude in both rivers; a Front Step pulse shape dominated in the Ésera whereas a Rectangle pulse shape was the most frequent in the Cinca. The Front Step shape had the highest ramping rates during the rising limb of the hydrograph and the shortest time to the maximum flow; whereas the Rectangle shape had higher duration and a larger volume of water released. Hydropeaks in the Ésera were less frequent (one per day) than in the Cinca (two per day). The river Ésera presented, in general, high‐magnitude hydropeaks, with double volume and duration, and three times larger up‐ramping rates and time between flow pulses. Overall, hydropeak shapes in the Ésera varied depending on the hydrological year and the season, while in the Cinca, shape distribution followed the same temporal pattern regardless of year and season; thus, hydropeaking in the Ésera appeared to be much more dependent on the annual hydrology (whether the year is wet or dry) than in the Cinca. Hydropeaking regimes were characterized based on three categories of variables: magnitude (flow‐based or hydrological variables), timing (duration), and frequency (occurrence). According to the variability of these variables, a total of three statistically significant groups were obtained in the Ésera, while two groups were identified in the Cinca. Hydropeaks can be statistically classified by their hydrological characteristics that in turn may have a direct effect on sediment entrainment and transport with implications to the ecological functioning of rivers. The different shape of the hydropeaks, however, will control the attenuation of the flows downstream and, consequently, the maintenance of the river's competence and capacity. This methodology provides a useful quantification of hydropeaking regimes to assess the potential impacts on physical and biological aspects of river systems.
Camera trapping with photos and videos: implications for ecology and citizen science
Authors: Green Sian E. , Stephens Philip A. , Whittingham Mark J. , Hill Russell A. 
Published: September 2022

AbstractCamera traps are increasingly used in wildlife monitoring and citizen science to address an array of ecological questions on a wide variety of species. However, despite the ability of modern camera traps to capture high‐quality video, the majority of studies collect still images, in part because of concerns with video performance. We conducted a camera trap survey of a forested landscape in the UK, using a grid of paired camera traps, to quantify the impact of using video compared to photos on the outcomes of ecological research and for participation and engagement of citizen scientists. Ecological outputs showed no difference between photo and video datasets, but comparison between expert and citizen science classifications showed citizen scientists were able to classify videos more accurately (average accuracy of 95% for video, 86% for photo). Furthermore, citizen scientists were more likely to volunteer additional information on age (provided for 61% videos and 30% photos) and sex (provided for 63% videos and 45% photos) of animals in video footage. Concerns over slow trigger speeds for videos did not appear to affect our datasets or the inferences gained. When combined with citizen science, video datasets are likely to be of higher quality due to increased classification accuracy. Consequently, we encourage researchers to consider the use of video for future camera‐trapping projects.