bluuebunny/crossref_metadata_2025_split huggingface dataset:
Difference in Antihypertensive Medication Pattern in the First Year Compared to More than a Year of Maintenance Hemodialysis: A Northern India Tertiary Care Experience
Authors: Chandra Abhilash , Rao Namrata , Srivastava Divya , Mishra Prabhaker 
Published: January 2022

Introduction
There is a high prevalence of hypertension in maintenance hemodialysis patients. Information regarding prevalent pattern of antihypertensive medications will help modify it to prevent future cardiovascular morbidity and mortality.

Materials and Methods
In this cross-sectional study, patients on maintenance hemodialysis, aged ≥18 years visiting Nephrology outpatient department (OPD) from April 2019 to May 2020 were included. The patients were divided into two groups based on their dialysis vintage, ≤12 months and >12 months. Their antihypertensive medication patterns and two-dimensional (2D) echocardiography (ECHO) findings were compared. Independent t-test was used to compare continuous variables. One-way analysis of variance was used to study the antihypertensive drug-dosing pattern in both the groups.

Results
Out of 250 patients, 131 had a dialysis vintage of ≤12 months, whereas 119 had a vintage of >12 months. There was no significant difference in the number of antihypertensive agents used in either of the vintage groups. Calcium channel blockers (87.02 and 89.07%, respectively, in ≤12 and >12 months' vintage groups) and β blockers (64.12 and 65.54%, respectively, in ≤12 and >12 months' vintage groups) were the commonly used antihypertensive agents. Metoprolol use was higher in ≤12 months' group, whereas carvedilol usage was higher in >12 months' group (p = 0.028). Mean pill burden was more than five in both the groups. Concentric left ventricular hypertrophy was significantly more common in >12 months' group. Renin–angiotensin system (RAS) blocking agent use was limited to 3% of patients.

Conclusion
This study shows a high antihypertensive pill burden in dialysis patients likely due to underlying chronic volume overload in addition to the perceived efficacy of certain class of drug in a frequent dosing pattern. Low use of RAS blocking agent was also underlined. This study highlights the need to bring about changes in the antihypertensive prescription pattern in line with the existing evidence.
Sarcopenia of Cirrhosis and the Therapeutic Potential of Transjugular Intrahepatic Portosystemic Shunt Creation
Authors: Schlansky Barry , Farsad Khashayar 
Published: January 2022

AbstractSarcopenia is a major sequela of cirrhosis, contributing to significant morbidity and mortality. Advances in body composition analysis using medical imaging have begun to identify changes in skeletal muscle and fat that are prognostic of the impact of sarcopenia on medical outcomes in cirrhosis and other pathologies. Recently, observational studies have shown a correlation between transjugular intrahepatic portosystemic shunt (TIPS) creation and a reversal of the progressive muscle loss in cirrhosis. This reversal is also associated with improved clinical outcomes and survival. This review summarizes current understanding of cirrhotic sarcopenia, and discusses the implications of TIPS creation in reversing this process.
Early antitumor activity of oral Langerhans cells is compromised by a carcinogen
Authors: Saba Yasmin , Aizenbud Itay , Matanes Daniela , Koren Noam , Barel Or , Zubeidat Khalid , Capucha Tal , David Eyal , Eli-Berchoer Luba , Stoitzner Patrizia , Wilensky Asaf , Amit Ido , Czerninski Rakefet , Yona Simon , Hovav Avi-Hai 
Published: January 2022

SignificanceOral cancer is often diagnosed at late stages, resulting in a poor prognosis of this disease. Understanding early carcinogenic events taking place during the development of oral cancer is, therefore, an important unmet clinical need. This study identifies an early anticancer protective role of oral Langerhans cells (LCs), the principal mononuclear phagocyte involved in immunosurveillance of the oral epithelium. Continuous exposure to the carcinogen 4NQO hampers the local differentiation of LCs, while other mononuclear phagocytes and T cells with immunosuppressive characteristics populate the epithelium, leading to the development of oral cancer. These findings reveal an initial step by which immunosurveillance is compromised by a carcinogen, which could facilitate novel diagnostic approaches to better detection of oral cancer.
Translating authorial presence
Authors: Shleykina Galina , Junnier Frances 
Published: January 2022

Abstract
Of increasing interest in cross-linguistic variation in academic discourse is the way in which writers use
first-person pronouns (FPPs) to promote their agency. While research has shown that language specific socio-cultural, rhetorical
and lexico-grammatical factors impact levels of self-concealment vs. self-promotion, less attention has been paid to the ways in
which translated texts are sensitive to these discoursal traditions. We address this gap by analyzing frequency, rhetorical use,
and grammatical form of FPPs in a corpus of research article (RA) abstracts in biology written by Russian and international
researchers in two peer-reviewed bilingual journals. Three subcorpora were analyzed: (i) L1 Russian abstracts; (ii) the same
abstracts translated into English; (iii) abstracts by international biologists in English from the same journals. The FPP tokens
were identified and their frequency, rhetorical use, and forms were compared. The results show significant differences between the
corpora which supports previous findings on cross-cultural variation in authorial presence in research genres. The results also
suggest that the translation not only transfers L1 linguistic code but also adds a stronger emphasis on author agency.
Implications for translating RAs into English as an exercise in linguistic, cognitive, and pragmatic equivalence as well as for
accommodating discourse conventions of English as a lingua franca of science are explored.
Traditional and current-prospective methods of agricultural plant diseases detection: A review
Authors: Khakimov A , Salakhutdinov I , Omolikov A , Utaganov S 
Published: January 2022

Abstract
As it is known, a significant part of the yield of agricultural crops is lost due to harmful organisms, including diseases. The article reveals the data on the widespread types of plant diseases (rot, wilting, deformation, the formation of tumors, pustules, etc.) and their symptoms. Early identification of the pathogen type of plant infection is of high significance for disease control. Various methods are used to diagnose pathogens of disease on plant. This article discusses the review of the literature data on traditional methods for diagnosis of plant pathogens, such as visual observation, microscopy, mycological analysis, and biological diagnostics or the use of indicator plants. Rapid and reliable detection of plant disease and identification of its pathogen is the first and most important stage in disease control. Early identification of the cause of the disease allows timely selection of the proper protection method and ensures prevention of crop losses. There are a number of traditional methods for identifying plant diseases, however, in order to ensure the promptness and reliability of diagnostics, as well as to eliminate the shortcomings inherent in traditional diagnostics, in recent years, new means and technologies for identifying pathogens have been developed and introduced into practice. As well as the article provides information on such innovative methods of diagnosis of diseases and identification of their pathogens, which are used widely in the world today, such as immunodiagnostics, molecular-genetic (and phylogenetic) identification, mass spectrometry, etc.
Effect of mycorrhizal provision and watering frequency on productivity and fresh material of forage sorghum (Sorghum bicolor (L.) Moench)
Authors: Mbeong Y S N , Umami N , Hanim C , Astuti A , Muhlisin  , Rahayu E R V 
Published: January 2022

Abstract
Sorghum is a cereal crop that has the potential to be developed as animal feed. Sorghum plant experiencing drought stress will decrease their productivity. Efforts to overcome this problem are by adding mycorrhizae. Mycorrhizae increase the ability of plants to adapt to the environment in the form of absorption of water and nutrients. This study aimed to determine the productivity of sorghum (plant height increase, plant length increase, number of leaves and stem diameter) and fresh weight of sorghum plant. The research treatments were mycorrhizal levels and watering frequency using a completely randomized design with a 3x3 factorial pattern. The mycorrhizal fungi provision consisted of three levels, namely without mycorrhizal (M0), mycorrhizal 10 g/polybag (M10), and mycorrhizal 20 g/polybag (M20). The frequency of watering consisted of watering everyday (A1), watering every four days (A4), and watering every eight days (A8). The provision of mycorrhizae significantly affected the productivity of sorghum and fresh weight of sorghum (p<0.05). The difference in watering frequency affected the increase in sorghum plant height (p<0.05). However, it did not significantly affect the increase in length, stem diameter, number of leaves, and fresh weight of sorghum. In conclusion, mycorrhizae can significantly improved the productivity of sorghum plants developed in areas with high drought levels.
The accuracy of several in vitro methods in estimating in vivo digestibility of the tropical dairy ration
Authors: Despal  , Manik D T P , Evvyernie D , Zahera R 
Published: January 2022

AbstractIn vitro digestibility methods have been developed to overcome problems in the in vivo digestibility measurement, but its accuracy should be tested in a local setting. In vitro methods developed by Tilley and Terry (T2), Theodorou (T3) and Sutardi (T4) have been compared to in vivo method (T1) in a block randomized design study. Four heifers FH (337.50 ± 45.87 kg BW) were used in T1, and two fistulated FH bulls (510 ± 20 kg BW) were used as inoculant sources in the in vitro methods. Dairy cattle ration consisted of 54.0% Napier grass and 46.0% concentrate with 58.8% DM, 12.1% ash, 10.0% CP, 3.3% EE, 26.5% CF, and 61.1% TDN. The observed parameters were ration fermentability (pH, NH3, and VFA concentration) and digestibility (DMD and OMD). The data were analyzed using analysis of variance (ANOVA) followed by the Tukey test. The correlation was made before regression analysis to estimate the in vivo parameters from the in vitro. The results showed that pH values are in the normal range (6.7 – 6.8), and insignificantly different between treatments (P>0.05). The concentration of NH3 and VFA were significantly different between the treatments (P<0.05), but T2 produced similar NH3 and VFA concentrations to T1. Similar results were also found in the DMD and OMD. Correlation analysis showed that pH value of T3 correlated significantly with T1, while DMD value of T4 correlated to T1. The T1 DMD (Y) could be estimated from T4 DMD (X) using formula Y (%) = y = -0.091x2+ 9.1632x - 168.4. It is concluded that tropical dairy feedstuffs in vitro digestibility using Tilley and Terry’s method produced similar result to in vivo digestibility method, but in vivo dry matter digestibility can be estimated accurately by in vitro dry matter digestibility using Sutardi method.
Optimization of benzyl amino purines (BAP) concentration and medium type on the induction of banana shoots (Musa acuminata Colla.) cv. Barangan Merah under in vitro condition
Authors: Setyowati M , Efendi  , Alfizar  , Kesumawati E 
Published: January 2022

Abstract
The use of optimum concentration of BAP and the right medium type can support shoot induction on the explant of banana sucker cv.Barangan Merah. The Research was conducted at the Laboratory of Tissue Culture, Faculty of Agriculture, Universitas Syiah Kuala. This research used a completely randomized 3x3 factorial design. The first factor was Benzyl Amino Purines (BAP) concentration at three levels of concentration, i.e. control, 3 mg.L-1, and 6 mg.L-1. The second factor was Musrahige & Skoog (MS) medium type at three levels, i.e. solid, solid-liquid, and liquid. Results showed that the BAP treatment of 3 mg.L-1 had the biggest response to the number of open midribs compared to other BAP treatments. The type of solid medium tends to shoot induction better than other types of medium. The contamination that occurred was 13.9% of the 72 explants planted. The contamination was caused by Mucor and Aspergillus fungi. The bacteria causing the contamination were gram positive bacteria (coccus) and gram-negative bacteria (coccus and bacilli).
Factors affecting the decision of potato farmers in adopting superior seeds in Bener Meriah District
Authors: Agussabti  , Rahmaddiansyah  , Deli A , Arida A , Mahda F A 
Published: January 2022

Abstract
Potato (Solanum tuberosum L) is one of the horticultural commodities with excellent opportunities for agribusiness and agroindustry development. The use of high-quality seeds and appropriate technology is still far from the reach of farmers. Generally, potato farmers in the Bener Meriah District use potato seeds from the previous production, but some consistently use superior seeds in every cultivation activity. This study analyses the factors that made farmers adopt superior seeds for potatoes in Bener Meriah. Based on the study results, the variables of age, education level, length of farming, land area, and the number of dependents had no significant effect on adopting superior potato seeds in Bener Meriah. At the same time, the variables of access to capital and farmer participation have a significant effect on farmers’ decisions to adopt superior potato seeds in Bener Meriah.
The effect of fed on feeding combination of the ark with ammonized citronella grass waste to the quality of lactated etawah crossbreed goat milk
Authors: Dzarnisa  , Ramaya A 
Published: January 2022

AbstractThis study aims to determine the effect of giving a combination of the ark with ammoniated citronella grass waste on the levels of protein, fat, lactose and density of lactatedEtawahcrossbreed goat milk. The design used in this study was a randomized block design (RBD) consisting of 5 treatments and 3 groups. The treatment consisted of P1 (0% ark: 8% ammoniated citronella grass waste), P2 (2% ark: 6% ammoniated citronella grass waste), P3 4% ark: 4% ammoniated citronella grass waste), P4 (6% ark: 2% citronella ammonia grass waste) and P5 (8% ark: 0% ammoniated citronella grass waste). The data obtained were analysed statistically using Microsoft Excel software. Based on the results of the research, giving the combination of the ark with ammoniated citronella grass waste shows no significant effect (P> 0.05) on the quality of milk which includes density, lactose level, protein level and fat level inEtawahcrossbreed goat (PE) milk. However, the quality test results showed an increasing trend when compared with the quality of PE goat’s milk without treatment The results of the data for each of the PE goat’s milk quality before given the feed treatment were 1.027; 3.34%; 3.42% and 6.40% for the density, lactose level, protein level and fat level. Meanwhile the results of the data for each of the PE goat milk quality after given the feed treatment got the best results, namely 1.030; 3.66%; 3.78% and 6.55% for the density, lactose level, protein level and fat level.
Environmental communication network on Indonesian forest fires on Twitter in pandemic COVID-19 era
Authors: Muslikhin Muslikhin , Evelina L W , Rizkiansyah M , Prawira I , Irawan R E 
Published: January 2022

Abstract
The study aims to reveal the communication network on Twitter about forest fires in Indonesia during the COVID-19 pandemic. The research method used is descriptive qualitative. The theory used in this research is communication networking. The analysis technique uses Social Networking Analysis or SNA. Conversation data on Twitter is pulled through emprit drones by entering keywords fire, forest, and land. The research findings show; Conversation volume was 617 conversations, with five actors mentioning the most, namely @VICE-ID, @BBCIndonesia, @totoroeksib, @GoldenMiru, and @ari_trismana with 16 conversations. Of the 617 conversations, 243 had negative sentiments, 368 had positive sentiments and 6 were neutral. The five words that appear the most in the discussion of forest and land fires are forest - hutan (with a small h) 459 times, land -lahan 147 times, Forest -Hutan (with large H) 80 times, disaster -bencana 60 times, and smoke -asap 56 times. During the 10 days of talking, there were 67 hashtags, with the top five being #hijabbugil, #eksibisionis, and # exhibition with 27 mentions, following #PreventedKarhutla with 16 mentions, and 13 mentions #KoperasiPerkuatPertuangan.
Syneresis, and acidity value of fermented goat milk added with beet (Beta vulgaris L.) juice using Lactobacillus rhamnosus
Authors: Yurliasni  , Hanum Z , Khairunnisa H 
Published: January 2022

AbstractThe purpose of this study was to determine the effect of adding beet juice in fermented goat’s milk usingLactobacillus rhamnosusbacteria on the acidity, syneresis value. This study applied a Complete Randomized Design (RAL) consisting of five treatments Control (P0), 2% of beet juice (P1), 4% of beet juice (P2), 6% of beet juice (P3), and 8% of beet juice (P4) with four repetitions. The data obtained were analysed using ANOVA (Analysis of Variance). If a significant difference is found, then Duncan’s multiple range (DMRT) test is conducted. The results showed that the addition of beet juice with a different percentage in fermented goat milk had significant effect (P<0.05) on syneresis but had a very significantly effect (P<0.01) on the pH value. The addition of 2% of Beet juice resulted in the lowest syneresis value of 9.88%. The low value of syneresis in this study was caused by the addition of beet juice which has high acidity, carbohydrate and protein content. The higher the lactic acid, the lower the pH and the denser the texture formed because the protein’s ability to bind water increases so that the syneresis formed is lower.
Optimizing the utilization of scad fish (Decapterus spp.) resource in northern coast of Aceh
Authors: Sofyan  , Farhan MD , Ginting LN 
Published: January 2022

Abstract
For ten years, the Scad fish production in the Northern Coast of Aceh has been increasing rapidly at 172.5%. This condition describes that the Scad fish resource exploitation is implemented under improper management that could encounter an overfishing case. This study aimed to analyze the Scad fish resource utilization level and recommend a management strategy to achieve an optimized Scad fish resource utilization in the Northern Coast of Aceh. This study was performed in the Ocean Fishing Port, Kutaraja, Banda Aceh. Bioeconomic analysis results showed that catching product and effort in MSY condition at 2,838.59 tons and 2,808 trips by economic rent was Rp23,902 million per year. In MEY condition, catching product at 2,748.01 ton with catching effort at 2,311 and economic rent was Rp25,056 million per year. The open-access condition of Scad fish resource with total catching effort at 5,386 trips and economic rent value obtained was Rp 0. Results demonstrated that the Scad fish resource utilization status in the Northern Coast of Aceh encounters biological and economical overfishing. The Scad fish resource management strategy for achieving MSY and MEY condition through input control and output control by establishing the total allowed catching product and catching quota.
Assessment cytotoxic assay of Rhizophora plants mangrove using brine shrimp (Artemia salina L) model
Authors: Indriaty I , Ginting B , Hasballah K , Djufri  
Published: January 2022

Abstract
Rhizophoraceae is the main family of mangroves as a source of bioactive compounds originating from the coast. Ethnophamacologically Rhizophoraceae has been used in various traditional medicine. Natural sources as anticancer from the Rhizophoraceae family are interesting to know. This study aimed to determine the cytotoxic bioactivity of methanolic extracts of roots, bark, leaves, and fruit/hypocotyl from five species of Rhizophoraceae (Bruguieria cylindrica, B. gymnorrhiza, Ceriops decandra, Rhizophora apiculata, and R. mucronata) from the Langsa mangrove forest, Aceh. The method used in this study was the Brine Shrimp Lethality Test (BSLT) bioassay using Artemia salina Leach at extract concentrations of 1, 10, 100, 500, and 1000 μg/ml. Samples were extracted using the maceration method and methanol as the solvent. The cytotoxic activity of 20 Rhizophoraceae methanol extracts showed that 12 extracts were toxic with an LC50 range of 31.5 - 934.9 μg/ml (based on LC50 ≤ 1000 μg/ml). The two extracts of which the closest to highly toxic (based on LC50 ≤ 30 μg/ml) were C. decandra bark showed LC50 of 31.5 μg/ml, and R. mucronata bark showed LC50 31.8 μg/ml. This shows that Rhizophoraceae extract has potential as a natural anticancer agent. In the five rhizophoraceae species, C. decandra was the most active compared to other species. In the four plant parts, the bark was the most toxic.
Bio-priming of Aceh local chili seeds in the effort to increase production and begomo virus resistance
Authors: Hafsah S , Yusnizar  , Nura  , Kaloko K S , Reza F , Firdaus  
Published: January 2022

Abstract
The purpose of this study was to determine whether P60 could induce resistance in local Aceh chili varieties to begomovirus and compared with national varieties. This research was conducted at the Experimental Farm, Genetics and Plant Breeding Laboratory, Faculty of Agriculture, Syiah Kuala University, Banda Aceh, from March to July 2021. This study used a factorial randomized block design. The tested factors consisted of two factors. The first factor is bio priming. The second factor consists of four local Aceh chili varieties, namely: V1 = Odeng, V2 = Lanyoe, V3 = Super Lamando and V4 = LamandoLapaben and one national variety, namely V5 = Baja F1 as a comparison variety. The results showed that the best local Aceh variety was LamandoLapaben for the variables of resistance response, incubation period, disease intensity, disease incidence, stem diameter, and crown width. The best local variety Aceh Lanyoe on plant height and dichotomous height parameters. Giving P60 can reduce the percentage of disease incidence by 52.00% and slow down the process of emergence of disease symptoms (incubation period) 27.11 DAP. The best combination treatment was the LamandoLapaben variety, which was 1.41 milligram Units-1 (Umg)-1.
Green synthesis of silver nanoparticles using Calotropis gigantea and its characterization using UV-Vis Spectroscopy
Authors: Kemala P , Idroes R , Khairan K , Tallei T E , Ramli M , Efendi R 
Published: January 2022

Abstract
The use of Calotropis gigantea from Ie Seu-Um, Aceh Besar geothermal area for silver nanoparticles (AgNPs) synthesized has been reported. The process of synthesis AgNPs can be carried out with chemical methods, physical methods, and green synthesis methods, but in this study, the process is focused on the green synthesis method using C. gigantea flowers and leaves extract from Ie Seu-Um geothermal area, Aceh Besar. Phytochemical analysis showed that C. gigantea leaves contain alkaloids, steroids, tannins, phenolics, and saponins, while the flowers of C. gigantea contain alkaloids, terpenoids, steroids, flavonoids, tannins, phenolics, and saponins. The reaction of the AgNPs formation was observed by colour change formed. AgNPs-C. gigantea flower extract dan AgNPs-C. gigantea leaves extract showed the reddish-brown and brownish-yellow solution respectively after 48 h incubation in dark condition at room temperature. The result of the reaction characterized using UV-Vis Spectrophotometry showed that the phenomenon of Surface plasmone resonance (SPR) occurs in the mixture of nanoparticles formed. The concentration of AgNO3 as a reagent affected the SPR phenomenon. The result showed that particles formed are the same size and shape.