bluuebunny/crossref_metadata_2025_split huggingface dataset:
Geometric-based nail segmentation for clinical measurements
Authors: Galmés Bernat , Moyà-Alcover Gabriel , Bibiloni Pedro , Varona Javier , Jaume-i-Capó Antoni 
Published: March 2022

AbstractA robust segmentation method that can be used to perform measurements on toenails is presented. The proposed method is used as the first step in a clinical trial to objectively quantify the incidence of a particular pathology. For such an assessment, it is necessary to distinguish a nail, which locally appears to be similar to the skin. Many algorithms have been used, each of which leverages different aspects of toenail appearance. We used the Hough transform to locate the tip of the toe and estimate the nail location and size. Subsequently, we classified the super-pixels of the image based on their geometric and photometric information. Thereafter, the watershed transform delineated the border of the nail. The method was validated using a 348-image medical dataset, achieving an accuracy of 0.993 and an F-measure of 0.925. The proposed method is considerably robust across samples, with respect to factors such as nail shape, skin pigmentation, illumination conditions, and appearance of large regions affected by a medical condition.
Optimal state space reconstruction via Monte Carlo decision tree search
Authors: Kraemer K. Hauke , Gelbrecht Maximilian , Pavithran Induja , Sujith R. I. , Marwan Norbert 
Published: March 2022

AbstractA novel idea for an optimal time delay state space reconstruction from uni- and multivariate time series is presented. The entire embedding process is considered as a game, in which each move corresponds to an embedding cycle and is subject to an evaluation through an objective function. This way the embedding procedure can be modeled as a tree, in which each leaf holds a specific value of the objective function. By using a Monte Carlo ansatz, the proposed algorithm populates the tree with many leafs by computing different possible embedding paths and the final embedding is chosen as that particular path, which ends at the leaf with the lowest achieved value of the objective function. The method aims to prevent getting stuck in a local minimum of the objective function and can be used in a modular way, enabling practitioners to choose a statistic for possible delays in each embedding cycle as well as a suitable objective function themselves. The proposed method guarantees the optimization of the chosen objective function over the parameter space of the delay embedding as long as the tree is sampled sufficiently. As a proof of concept, we demonstrate the superiority of the proposed method over the classical time delay embedding methods using a variety of application examples. We compare recurrence plot-based statistics inferred from reconstructions of a Lorenz-96 system and highlight an improved forecast accuracy for map-like model data as well as for palaeoclimate isotope time series. Finally, we utilize state space reconstruction for the detection of causality and its strength between observables of a gas turbine type thermoacoustic combustor.
Metal-ligand bonding in bispidine chelate complexes for radiopharmaceutical applications
Authors: Kovács Attila 
Published: March 2022

AbstractThe complexes of selected radionuclides relevant for nuclear medicine (InIII, BiIII, LuIII, AcIIIand in addition LaIIIfor comparative purposes) with the octadentate (6,6′-((9-hydroxy-1,5-bis(methoxycarbonyl)-2,4-di(pyridin-2-yl)-3,7-diazabicyclo[3.3.1]nonane-3,7-diyl)bis(methylene))dipicolinic acid) ligand, H2bispa2, have been studied by density functional theory calculations modelling both isolated and aqueous solution conditions. The properties in focus are the encapsulation efficiency of the ligand for the different-size metals (M), the differences in bonding with the various MIIIions analysed using Bader’s atoms in molecules theory and the possibility and characteristics of nona- and decacoordination by H2O ligands. The computed results confirmed strong steric effects in the case of the In complex excluding higher than octacoordination. The studied properties depend strongly on the interplay of the sizes and electronic structures of the MIIIions. The computations support high stability of the complexes in aqueous solution, where also the solvation energies of the MIIIions (as dissociation products) play a significant role.
NMR Relaxation Modelling in Porous Media with Dual-Scale-Resolved Internal Magnetic Fields
Authors: Cui Yingzhi , Shikhov Igor , Arns Christoph H. 
Published: March 2022

AbstractA pore-scale forward modelling approach for NMR relaxation responses of sandstones incorporating their dual-scale nature is presented. The approach utilises X-ray micro-CT images to capture inter-granular porosity and scanning electron microscopy images to reconstruct clay regions via a resolved clay micro-structure model. A key to calculating the NMR response with resolved clay micro-structure is the development of a dual-scale internal magnetic field calculation. This is achieved by a separation of near- and far-field effects in a dipole approximation of the internal field with periodic clay micro-structures, the latter of which take local clay pocket porosity into account. Tri-linear interpolation of the micro-CT image before calculation of the internal magnetic field further reduces errors in the transition regions between coarse- and fine-scale structure, with final discretisation level matching the fine-scale clay micro-structure model across the whole domain. The method is validated against direct calculations of model media at full resolution and applied to Bentheimer sandstone. Measured and simulated NMR $$T_2$$

T
2

relaxation responses, including relaxation time distribution shape, are in excellent agreement and distributions of internal magnetic field gradients at the highest spatial resolution as well as diffusion-averaged effective gradients are reported.
Systematic literature review of applications and usage potentials for the combination of unmanned aerial vehicles and mobile robot manipulators in production systems
Authors: Sinnemann Jannis , Boshoff Marius , Dyrska Raphael , Leonow Sebastian , Mönnigmann Martin , Kuhlenkötter Bernd 
Published: March 2022

AbstractThe cooperation of Unmanned Aerial Vehicles (UAVs) and Mobile Robot Manipulators (MRMs) offers enormous possibilities to modern industry. It paves the way for logistics, cooperative assembling or manipulation and will provide even more flexibility and autonomy to today’s manufacturing processes. Currently, some systematic literature reviews exist that provide an overview on research fields and gaps in the field of UAVs and MRMs. However, an investigation of the research landscape for combined use of UAVs and MRMs does not exist to the best of the authors’ knowledge. Therefore, in this paper, a systematic review of the current research landscape for the combined use of UAV and MRM is conducted to finally identify fields of action that need to be addressed in the future to harness the full potential.
On the Modeling and Simulation of Variable-Length Pendulum Systems: A Review
Authors: Yakubu Godiya , Olejnik Paweł , Awrejcewicz Jan 
Published: March 2022

AbstractA comprehensive review of variable-length pendulums is presented. An attempt at a unique evaluation of current trends in this field is carried out in accordance with mathematical modeling, dynamical analysis, and original computer simulations. Perspectives of future trends are also noted on the basis of various concepts and possible theoretical and engineering applications. Some important physical concepts are verified using dedicated numerical procedures and assessed based on dynamical analysis. At the end of the review, it is concluded that many variable-length pendulums are very demanding in the modeling and analysis of parametric dynamical systems, but basic knowledge about constant-length pendulums can be used as a good starting point in providing much accurate mathematical description of physical processes. Finally, an extended model for a variable-length pendulum’s mechanical application being derived from the Swinging Atwood Machine is proposed. The extended SAM presents a novel SAM concept being derived from a variable-length double pendulum with a suspension between the two pendulums. The results of original numerical simulations show that the extended SAM’s nonlinear dynamics presented in the current work can be thoroughly studied, and more modifications can be achieved. The new technique can reduce residual vibrations through damping when the desired level of the crane is reached. It can also be applied in simple mechatronic and robotic systems.
The reporting standards of randomised controlled trials in leading medical journals between 2019 and 2020: a systematic review
Authors: McErlean Mairead , Samways Jack , Godolphin Peter J. , Chen Yang 
Published: March 2022

AbstractRandomised controlled trials (RCTs) are the gold standard study design used to evaluate the safety and effectiveness of healthcare interventions. The reporting quality of RCTs is of fundamental importance for readers to appropriately analyse and understand the design and results of studies which are often labelled as practice changing papers. The aim of this article is to assess the reporting standards of a representative sample of randomised controlled trials (RCTs) published between 2019 and 2020 in four of the highest impact factor general medical journals. A systematic review of the electronic database Medline was conducted. Eligible RCTs included those published in the New England Journal of Medicine, Lancet, Journal of the American Medical Association, and British Medical Journal between January 1, 2019, and June 9, 2020. The study protocol was registered on medRxiv (https://doi.org/10.1101/2020.07.06.20147074). Of a total eligible sample of 497 studies, 50 full-text RCTs were reviewed against the CONSORT 2010 statement and relevant extensions where necessary. The mean adherence to the CONSORT checklist was 90% (SD 9%). There were specific items on the CONSORT checklist which had recurring suboptimal adherence, including in title (item 1a, 70% adherence), randomisation (items 9 and 10, 56% and 30% adherence) and outcomes and estimation (item 17b, 62% adherence). Amongst a sample of RCTs published in four of the highest impact factor general medical journals, there was good overall adherence to the CONSORT 2010 statement. However there remains significant room for improvement in areas such as description of allocation concealment and implementation of randomisation.
Development and Optimization of an HPLC-PDA Method for the Determination of Major Cannabinoids in Hemp (Cannabis sativa L.) Essential Oil Obtained by Hydrodistillation
Authors: Piani Barbara , Ferfuia Claudio , Bortolomeazzi Renzo , Verardo Giancarlo , Baldini Mario 
Published: March 2022

AbstractThe use of hemp (Cannabis sativa L.) essential oil (EO) has shown a significant increase in interest and use during recent years. In this work, a new and simple reversed-phase HPLC with photodiode-array (PDA) detector method has been developed and optimized for the detection and quantification of cannabidiolic acid (CBDA), cannabidiol (CBD), cannabinol (CBN), Δ9-tetrahydrocannabinol (Δ9-THC), and Δ9-tetrahydrocannabinolic acid (THCA). The cannabinoids were extracted from the EO by partition with n-hexane and water, followed by sonication, evaporation to dryness under nitrogen, and reconstitution with methanol:chloroform (9:1, v/v) before HPLC-PDA analysis. The method shows good selectivity and robustness, linearity in the range 0.5–100 mg L−1 with R2 higher than 0.999 for all cannabinoids analyzed, LOD of 0.11–0.16 mg L−1, and LOQ of 0.35–0.48 mg L−1. The recovery was between 78 and 100% and the intra-day and intermediate precision, expressed as relative standard deviation (RSD), was < 4% and 4–10%, respectively.
The Dynamics of Multidimensional Poverty in a Cohort of Irish Children
Authors: Madden David 
Published: March 2022

AbstractThis paper examines multidimensional poverty for three waves of a cohort of Irish children ranging from ages 9 to 17. Poverty is measured over the dimensions of health, education and family resources and both unidimensional and multidimensional poverty is examined. Both show a clear gradient with respect to maternal education. The dynamics of both unidimensional and multidimensional poverty are also analysed. The greatest degree of mobility is observed with respect to family resources. Mobility also is higher for children whose mothers have lower levels of education, with net movements into rather than out of poverty.
Electrical, Thermal, and Mechanical Characterization of Hot Coined Carbon Fiber Reinforced Pure Aluminium Composites
Authors: Eid Mostafa , Kaytbay Saleh , El-Assal Ahmed , Elkady Omayma 
Published: March 2022

AbstractPoor interfacial structure and severe agglomerations of carbon fiber (CF) are significant problems that face carbon fiber reinforced aluminium (CF/Al) composites. Thus, CF was surface modified with nano copper particles (Cu) to overcome these problems. Two groups of CF/Al composites (uncoated and coated) at different weight percentages of reinforcement (0, 5, 10, 15, and 20) were fabricated using the planetary ball milling method and then uniaxially hot coined at 550 ℃ under 700 MPa. The results showed that CF refined the crystallite size of the Al matrix, and no $${\mathrm{Al}}_{4}{\mathrm{C}}_{3}$$

Al
4

C
3

or $${\mathrm{Al}}_{2}\mathrm{Cu}$$

Al
2

Cu

were detected in XRD patterns. The density and thermal expansion of composites reduced with increasing CF percentage in all samples. The electrical and thermal conductivities are improved up to 10 wt% of uncoated reinforcement and 15 wt% of coated one. The mechanical test results revealed that by increasing CF, the compressive strength of composites decreased while the wear properties improved for both groups. Cu deposition on CF improved the bonding between reinforcement and matrix, producing composites with better interfacial bonding, fewer agglomerations and porosity, and higher values of the properties of the composites.
Graphic Abstract
Preparation and characterization of carbon fiber reinforced aluminium composites by hot coining technique
Vulnerability Conditions in a Cohort of Men Who Have Sex with Men Who Engage in Chemsex in Barcelona City: a Cross-Sectional Study
Authors: De La Mora Lorena , Laguno Montserrat , De Lazzari Elisa , Ugarte Ainoa , Leal Lorna , Torres Berta , González-Cordón Ana , Inciarte Alexy , Ambrosioni Juan , Escalante Zoraida , Rodriguez Ana , Martinez Esteban , Blanco José L. , Blanch Jordi , Miquel Laia , Bosch Jordi , Short Duncan , Mallolas Josep , Martinez-Rebollar Maria 
Published: March 2022

Abstract
Introduction
Chemsex is a dynamic phenomenon with cultural variation. There is limited information about its prevalence and specific characteristics in our geographical area.

Methods
In this cross-sectional study of a series of gay, bisexual, and other men who have sex with men (gbMSM) who engaged in chemsex and were attending the Hospital Clinic of Barcelona, Spain, between March 2018 and May 2019, we aimed to identify potential vulnerabilities and describe the profiles of individuals who engaged in chemsex in our site. Baseline clinical and epidemiological characteristics related to HIV, HCV, STIs, sexual practices, and drug consumption were evaluated. A sub-analysis considering vulnerability conditions was completed.

Results
We included 161 participants: 67% were migrants and 48% were Latin American. A total of 150 participants were people living with HIV (PLWH), and 13% had a detectable HIV viral load (VL). The prevalence of HCV infection was 37%. Slamming practice was reported by 20% of the participants. Migrants from Latin America were younger, had a lower percentage of university education, and more frequently had detectable HIV-VLs and syphilis. HCV-positive participants reported more injecting drug use, versatile fisting practices, and syphilis. Slam users consumed more methamphetamine and mephedrone, had significantly higher HIV-VLs when detectable, and reported less sober sex.

Conclusion and Policy Implications
We identified certain baseline characteristics of our chemsex cohort that may confer a profile of greater vulnerability, which must be addressed in a personalized way when attempting damage reduction and a global approach to the practice of chemsex at our site. Access to specialized and interdisciplinary services with cultural competence in the complexity of the phenomenon should be guaranteed to these individuals for better management.
Postsurgical complications after robot-assisted transaxillary thyroidectomy: critical analysis of a large cohort of European patients
Authors: Rossi Leonardo , Buoni Valentina , Fregoli Lorenzo , Papini Piermarco , De Palma Andrea , Materazzi Gabriele 
Published: March 2022

AbstractIn the last decade, robot-assisted trans-axillary thyroidectomy has spread rapidly and has been proven to be a safe and effective procedure. However, several case series have reported new complications that have led to criticism regarding this approach. This study analyzed the incidence of complications in a large cohort of European patients. We enrolled all patients who underwent robot-assisted trans-axillary thyroidectomy from 2012 to 2020 at the University Hospital of Pisa Department of Endocrine Surgery. We analyzed complications and divided them into 2 groups. Group A included conventional complications, such as transient or permanent recurrent laryngeal nerve palsy, transient or permanent hypocalcemia, hemorrhage, and tracheal injury. Group B included unconventional complications, such as brachial plexus palsy, track seeding, seroma, great vessels injury, and skin flap perforation. There were 31 postsurgical complications (5.7%). Group A included 25 complications (4.6%): transient and permanent recurrent laryngeal nerve palsy occurred in 7 patients (1.3%) and in 1 (0.2%), respectively; transient and permanent hypocalcemia occurred in 9 patients (1.7%) and in 1 (0.2%), respectively. Postoperative bleeding occurred in 6 patients (1.1%) and tracheal injury in 1 (0.2%). Group B included 6 complications (1.1%): 1 patient with brachial plexus injury (0.2%), 1 with track seeding (0.2%), and 4 with seroma (0.7%). Robotic trans-axillary thyroidectomy is a safe approach with a risk of postoperative complications comparable to the conventional technique. Almost all complications after a novel introduction are anecdotal. With an accurate patient selection, high-volume institutions with experienced surgeons can perform this technique safely.
Real-world evaluation of sodium-glucose co-transporter-2 inhibitors and dipeptidyl peptidase-4 inhibitors for managing type 2 diabetes mellitus: a retrospective multi-ethnic cohort study
Authors: Goh Louise Gek Huang , Sun Jiandong , Ong Benjamin Shao Kiat , Khoo Daphne , Sum Chee Fang , Ng Kwong 
Published: March 2022

Abstract

Purpose
Sodium-glucose co-transporter-2 (SGLT2) inhibitors and dipeptidyl peptidase-4 (DPP4) inhibitors are increasingly used as second-line therapies in patients with type 2 diabetes. The aim of this study was to assess the real-world effects of SGLT2 inhibitors in a multi-ethnic population in Singapore.

Methods
This retrospective cohort study examined patients diagnosed with and treated for diabetes from the Ministry of Health’s administrative database. Differences in outcomes between treatment groups were assessed using Poisson regression. Demographics, clinical characteristics, previous diagnoses and hospitalisations, and diabetes medication history were used for propensity score matching. Subgroup analyses by ethnicity were performed. Effect size was estimated using risk ratios (RRs) with 95% confidence intervals (CIs).

Results
Patients initiating SGLT2 inhibitors were more likely to achieve glycaemic control target than DPP4 inhibitor-treated patients (RR 1.09; 95% CI 1.04, 1.14). This was observed only in patients of Chinese ethnicity. A higher risk of diabetic ketoacidosis in SGLT2 inhibitor initiators was not observed. SGLT2 inhibitors were associated with reduced risk of hypoglycaemia (RR 0.69; 95% CI 0.59, 0.82) and urinary tract infection (RR 0.52; 95% CI 0.43, 0.63) but was not statistically significant for hypoglycaemia in Malay patients. Compared to DPP4 inhibitors, SGLT2 inhibitors were associated with 12% and 34% reduction in any-cause hospitalisation and all-cause mortality, respectively, potentially resulting in more than $50 million savings over 10 years.

Conclusion
SGLT2 inhibitors were associated with improvements in glycaemic control, reduced risk of complications, and was well tolerated. Ethnicity also plays a role and should be considered in future studies.
Docking Manoeuvre Control for CubeSats
Authors: Stesina Fabrizio , Corpino Sabrina , Novara Carlo , Russo Simone 
Published: March 2022

AbstractRendezvous and docking missions of small satellites are opening new scenarios to accomplish unprecedented in-obit operations. These missions impose to win the new technical challenges that enable the possibility to successfully perform complex and safety–critical manoeuvres. The disturbance forces and torques due to the hostile space environment, the uncertainties introduced by the onboard technologies and the safety constraints and reliability requirements lead to select advanced control systems. The paper proposes a control strategy based on Model Predictive Control for trajectory control and Sliding Mode Control for attitude control of the chaser in last meters before the docking. The control performances are verified in a dedicated simulation environment in which a non-linear six Degrees of Freedom and coupled dynamics, uncertainties on sensors and actuators responses are included. A set of 300 Monte Carlo Simulation with this Non-Linear system are carried out, demonstrating the capabilities of the proposed control system to achieve the final docking point with the required accuracy.
“Belly Only Pregnancy” content on social media and in internet blogs: a qualitative analysis on its definition and potential risks and benefits
Authors: Steube Felizia , Löwe Bernd , Weigel Angelika 
Published: March 2022

Abstract
Purpose
Social media enlarge the impact of health and fitness trends on body image and lifestyle choices, also in birthing parents. A new and yet to investigate social media trend addressing expectant mothers is “Belly Only Pregnancy”. This qualitative study sought to define this new trend and clarify whether content related to this trend might disrupt body image or eating habits in expectant mothers.

Methods
Picture and text data were gathered on a key day by screening Instagram and blog posts including or linking #bellyonlypregnancy. The identified data were categorized applying qualitative content analysis using MAXQDA software version 2018.

Results
Three hundred and fifty-one Instagram and eight blog posts were included. Our qualitative analysis’ results indicated that the term “Belly Only Pregnancy” was used for describing: (1) The phenotype of an athletic woman whose abdominal size enlarges during pregnancy while not gaining excessive fat tissue. (2) An active lifestyle during pregnancy consisting of healthy nutrition and regular exercise pursuing goals like fast weight loss post-partum. Also, bodily, and mental gestational changes and the feasibility of this lifestyle were discussed.

Conclusion
A “Belly Only Pregnancy” allegorizes an ideal body type for expecting mothers. Especially women with increased vulnerability for an eating disorder might be negatively affected by the consumption of content linked to this trend. However, the positive effects of a healthy diet and exercise should not be denied keeping into account the increasing prevalence of obesity and gestational diabetes.

Level of evidence
Level III: Evidence obtained from cohort or case-control analytic studies.