bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlation between Uniaxial Compressive Strength and Point Load Strength of Penang Island Granites
Authors: Mohamad J D , Abang Hasbollah D Z , Mohd Taib A , Dan M F , Jusoh S N , Mat Said K N 
Published: February 2022

Abstract
Uniaxial compressive strength (UCS) is one of the most widely used strength parameters in geotechnical design. The value is obtained through direct testing method, carried out through careful procedures of testing in a laboratory setting. As such, it is relatively more expensive, more tedious and requires longer time to complete. Considering that UCS is highly important, Engineers often utilize indirect methods, namely the Point Load Test, to obtain the Point Load Index Strength (Is(50)). From this test, the results are correlated in order to predict the UCS value. One of the general correlations is provided by ISRM where UCS=20-25 Is(50). However, it is highly contested as it is not universal for all types of rocks. The main focus of this research is to find the correlation of UCS and Is(50) in the Penang Island area. This research would also attempt to classify the granites according to strength. This study showed that the Penang Island Granites are “weak to very strong” granites with UCS values between 24.76 to 156.82MPa. The granites from the North Pluton are classified as “medium strong to very strong” with UCS values between 37.11 to 156.82MPa. The granites from the South Pluton are classified as “weak to very strong” with UCS values between 24.76 to 141.59 MPa. The recommended correlation between UCS and Is(50) are (1) Overall: 8.385 Is(50) + 30.016 (2) North Pluton: 7.93 Is(50)+ 35.606 (3) South Pluton: 9.03Is(50)+20.138.
Tunnel Progression Effects to the Ground Surface and the Adjacent Pile
Authors: Zahid M A , Jusoh S N , Rahim A , Hezmi M A , Yunus N Z M , Mat Said K , Shahrin M I 
Published: February 2022

AbstractTunnelling close to existing structure in urban area has become unavoidable. The progression tunneling activities induced ground movement and might affect the integrity of existing structure especially the one lies within the tunneling influence zone. It may cause catastrophic failures of structures and can cause losses of human lives. Therefore, considering its risk, this study focuses on the tunnel-soil-pile interaction by performing a physical model testing. By conducting a series of laboratory tests, the ground subsidence and pile behavior is presented herein. For a twice diameter distance of tunnel and pile, the pile axial settlement is 0.04% of the tunnel diameter respectively, while the maximum pile bending moment is 4928. 93kN.m. Maximum ground settlement is 0.56% respectively to tunnel diameter. To sum up, the axial displacement of pile decreases when the pile located further away from the tunneling zone. Similarly, the ground surface subsidence decreases when the pile location is more in distance during the tunneling advancement.
Effects of Lime on the Compaction Characteristics of Lateritic Soil in UTM, Johor
Authors: Rizal N H A , Hezmi M A , Razali R , Wahab N A , Roshan M J , Rashid A S A , Hasbollah D Z A 
Published: February 2022

AbstractLime has been investigated as a ground improvement material for soils, particularly for road construction, as an alternative to soil cement stabilisation. However, the effect of lime on lateritic soil compaction characteristics is not completely defined. In this article, soil samples from Universiti Teknologi Malaysia (UTM), Skudai, Johor were subjected to a variety of engineering tests, including specific gravity, sieve analysis, Atterberg’s limit, and compaction. According to the results of Atterberg’s Limit, lateritic soil has a plasticity index (PI), a plastic limit (PL), and a liquid limit (LL) of 19, 46, and 65, respectively. The obtained specific gravity value is 2.79. Compaction tests were conducted on untreated and lime-treated soils with lime additions of 3%, 5%, 7%, and 9%, respectively, using an automatic compactor. The OMC and MDD values for untreated laterite are 28% and 1.46 g/cm3, respectively. However, as the lime content increases, the OMC increases slightly while the MDD decreases. The dry density of lime-laterite soil decreases from 1.47 to 1.38 g/cm3, but the moisture content increases slightly from 27% to 31%. The MDD of soil treated with 5% lime is lower than that of lateritic soil in its natural state.
Assessment on Recent Landslide Susceptibility Mapping Methods: A Review
Authors: Manan W A A , Rashid A S A , Abdul Rahman M Z A , Khanan M F A 
Published: February 2022

Abstract
Landslide is a destructive natural hazard that causes severe property loss and loss of lives. Numerous researchers have developed landslide susceptibility maps in order to forecast its occurrence, particularly in hill-site development. Various quantitative approaches are used in landslide susceptibility map production, which can be classified into three categories; statistical data mining, machine learning and deterministic approach. In this paper, we choose two regular models in each category, which are Weight of Evidence (WoE) and Frequency Ratio (FR), Artificial Neutral Networks (ANN) and Support Vector Machines (SVM), Shallow Landsliding Stability Model (SHALSTAB) and YonSei-Slope (YS-Slope). Discussion and assessment on these models are based on relevant literature.
Characterization of Subgrade Soil of Lowland Areas of Semarang City
Authors: Rochim A , Fitriyana L 
Published: February 2022

Abstract
The northern part of Semarang city has been suffering a lot from settlement and inundation caused by rainfall and tidal flood. The settlement is predicted to emerge from the subgrade soil containing soft soil with low bearing capacity and high compressibility. This study aims to characterize subgrade soil of lowland areas of Semarang city. In order to define the depth of soft soil, site class, soil classification, and the settlement, soil data was taken from twelve locations distributed in five sub districts of Semarang lowland areas. The minimum depth of subgrade soil is 30 m below the ground surface. To predict the settlement, subgrade soil was loaded by a surcharge load of 80 kPa, and a safety factor of 2 was taken into account. The analysis was based on N-SPT, cone resistance, index properties, and engineering properties. The result shows that the subgrade soil of Semarang lowland areas is dominated by soft clay with a depth of 5 m to 20 m with the site class from SE to SD. Soil is classified as CL and CH. The predicted settlement is from 0.321 m (lasts one year) to 1.395 m (lasts 13 years).
Observation of Gaussian quantum correlations existence of photons under linear beam splitter
Authors: Eshete Sitotaw 
Published: February 2022

Abstract
In this paper, we investigate the creation of quantum correlations such as entanglement, the Gaussian quantum discord and quantum steering in a quantum system under consideration via the linear beam splitter with squeezed thermal and a single-mode Gaussian states at the inputs. This quantum system generates bright entangled output two-mode light. Specifically, the quantum entanglement can be enhanced through increasing the purity of the Gaussian state and the squeezing parameter at the input states. The quantum correlations reveal similar characteristics for each case. That means when we increase the non-classicality, purity and squeezing parameter, the quantum correlations show enhanced profile. On the other hand, upon increasing the mean thermal photon number at the input, the quantum correlations indicate inverse relation.
Optically controlled grasping-slipping robot moving on tubular surfaces
Authors: Guo Hongshuang , Zeng Hao , Priimagi Arri 
Published: February 2022

Abstract
Stimuli-responsive polymers provide unmatched opportunities for remotely controlled soft robots navigating in complex environments. Many of the responsive-material-based soft robots can walk on open surfaces, with movement directionality dictated by the friction anisotropy at the robot-substrate interface. Translocation in one-dimensional space such as on a tubular surface is much more challenging due to the lack of efficient friction control strategies. Such strategies could in long term provide novel application prospects in, e.g. overhaul at high altitudes and robotic operation within confined environments. In this work, we realize a liquid-crystal-elastomer-based soft robot that can move on a tubular surface through optical control over the grasping force exerted on the surface. Photoactuation allows for remotely switched gripping and friction control which, together with cyclic body deformation, enables light-fueled climbing on tubular surfaces of glass, wood, metal, and plastic with various cross-sections. We demonstrate vertical climbing, moving obstacles along the path, and load-carrying ability (at least 3 × body weight). We believe our design offer new prospects for wirelessly driven soft micro-robotics in confined spacing.
Thermoelectric properties of organic thin films enhanced by π–π stacking
Authors: Wang Xintai , Sangtarash Sara , Lamantia Angelo , Dekkiche Hervé , Forcieri Leonardo , Kolosov Oleg V , Jarvis Samuel P , Bryce Martin R , Lambert Colin J , Sadeghi Hatef , Robinson Benjamin J 
Published: February 2022

Abstract
Thin films comprising synthetically robust, scalable molecules have been shown to have major potential for thermoelectric energy harvesting. Previous studies of molecular thin-films have tended to focus on massively parallel arrays of discrete but identical conjugated molecular wires assembled as a monolayer perpendicular to the electrode surface and anchored via a covalent bond, know as self-assembled monolayers. In these studies, to optimise the thermoelectric properties of the thin-film there has been a trade-off between synthetic complexity of the molecular components and the film performance, limiting the opportunities for materials integration into practical thermoelectric devices. In this work, we demonstrate an alternative strategy for enhancing the thermoelectric performance of molecular thin-films. We have built up a series of films, of controlled thickness, where the basic units—here zinc tetraphenylporphyrin—lie parallel to the electrodes and are linked via π–π stacking. We have compared three commonly used fabrications routes and characterised the resulting films with scanning probe and computational techniques. Using a Langmuir-Blodgett fabrication technique, we successfully enhanced the thermopower perpendicular to the plane of the ZnTPP multilayer film by a factor of 10, relative to the monolayer, achieving a Seebeck coefficient of −65 μV K−1. Furthermore, the electronic transport of the system, perpendicular to the plane of the films, was observed to follow the tunnelling regime for multi-layered films, and the transport efficiency was comparable with most conjugated systems. Furthermore, scanning thermal microscopy characterisation shows a factor of 7 decrease in thermal conductance with increasing film thickness from monolayer to multilayer, indicating enhanced thermoelectric performance in a π–π stacked junction.
Quantum Technologies for Engineering: the materials challenge
Authors: Goh Kuan Eng Johnson , Krivitsky Leonid A , Polla Dennis L 
Published: February 2022

Abstract
The materials challenge is often a major hurdle for translating good ideas in science into technologies. This is no different in the arena of quantum technologies which has seen a resurgence of interest in the last decade. This perspective provides a unique insight into the recent collaborative works by research groups in Singapore to surmount key quantum materials and processing bottlenecks that have impeded quantum technologies in the areas of sensing, computing, and communications. We highlight recent important materials related breakthroughs that have made possible novel advancements such as integrated ion traps, light frequency conversion, highly efficient cryogenic contacts to atomically thin quantum devices, and gate defined quantum dots, to name just a few. We also discuss the potential applications and conclude with our perspective on the remaining challenges to be addressed and the prospects enabled by these materials advances for future collaborations and co-developments to advance quantum technologies.
Ultrasound Analyses of the Dorsal Hands for Volumetric Rejuvenation
Authors: Hung Yi-Teng , Cheng Chun-Yu , Chen Chun-Bing , Huang Yau-Li 
Published: February 2022

Abstract

Background
Volumetric hand rejuvenation of the dorsal hands is increasingly applied for aged, skeletonized dorsal hand skin, with prominent veins, tendons, and joints due to volumetric loss of subcutaneous fat. However, the aging process of the fatty laminae remains unexplored.

Objectives
The aim of this study was to investigate the impact of aging and potential determinants on the fatty laminae to improve the therapeutic effect of volumetric injection.

Methods
This cross-sectional study enrolled 105 Taiwanese participants aged ≥20 years, divided into 5 decade-based age groups. A single blinded practitioner measured the thicknesses of the dorsal superficial lamina (DSL), dorsal intermediate lamina (DIL), and dorsal deep lamina (DDL) by ultrasonography. The potential determining factors of the laminae thickness (age, sex, BMI, and hand dominance) were analyzed.

Results
The thicknesses of the 3 laminae decreased with age, with the mean decrease in thickness from the 20s to &gt;60 years of the DSL, DIL, and DDL being 0.21 mm (30.0%), 1.38 mm (63.89%), and 0.31 mm (20.95%), respectively. The decrease in DIL thickness was the greatest and most significant in subjects aged &gt;30 years. Multiple linear regression analysis showed age to be the only determinant of thickness for the 3 laminae (all P &lt; 0.001), although the DIL was significantly thicker in men (P &lt; 0.001).

Conclusions
Volumetric fat loss was noted in the 3 fatty laminae of dorsal hands during aging; the DIL showed the greatest progressive fat loss after the age of 30. Volumetric rejuvenation of the 3 laminae may result in the most aesthetic appearance, especially in women.
A review of machine learning approaches for drug synergy prediction in cancer
Authors: Torkamannia Anna , Omidi Yadollah , Ferdousi Reza 
Published: February 2022

AbstractCombinational pharmacotherapy with the synergistic/additive effect is a powerful treatment strategy for complex diseases such as malignancies. Identifying synergistic combinations with various compounds and structures requires testing a large number of compound combinations. However, in practice, examining different compounds by in vivo and in vitro approaches is costly, infeasible and challenging. In the last decades, significant success has been achieved by expanding computational methods in different pharmacological and bioinformatics domains. As promising tools, computational approaches such as machine learning algorithms (MLAs) are used for prioritizing combinational pharmacotherapies. This review aims to provide the models developed to predict synergistic drug combinations in cancer by MLAs with various information, including gene expression, protein–protein interactions, metabolite interactions, pathways and pharmaceutical information such as chemical structure, molecular descriptor and drug–target interactions.
MGF6mARice: prediction of DNA N6-methyladenine sites in rice by exploiting molecular graph feature and residual block
Authors: Liu Mengya , Sun Zhan-Li , Zeng Zhigang , Lam Kin-Man 
Published: February 2022

AbstractDNA N6-methyladenine (6mA) is produced by the N6 position of the adenine being methylated, which occurs at the molecular level, and is involved in numerous vital biological processes in the rice genome. Given the shortcomings of biological experiments, researchers have developed many computational methods to predict 6mA sites and achieved good performance. However, the existing methods do not consider the occurrence mechanism of 6mA to extract features from the molecular structure. In this paper, a novel deep learning method is proposed by devising DNA molecular graph feature and residual block structure for 6mA sites prediction in rice, named MGF6mARice. Firstly, the DNA sequence is changed into a simplified molecular input line entry system (SMILES) format, which reflects chemical molecular structure. Secondly, for the molecular structure data, we construct the DNA molecular graph feature based on the principle of graph convolutional network. Then, the residual block is designed to extract higher level, distinguishable features from molecular graph features. Finally, the prediction module is used to obtain the result of whether it is a 6mA site. By means of 10-fold cross-validation, MGF6mARice outperforms the state-of-the-art approaches. Multiple experiments have shown that the molecular graph feature and residual block can promote the performance of MGF6mARice in 6mA prediction. To the best of our knowledge, it is the first time to derive a feature of DNA sequence by considering the chemical molecular structure. We hope that MGF6mARice will be helpful for researchers to analyze 6mA sites in rice.
Integrated Genome Browser App Store
Authors: Shanbhag Sameer , Patil Riddhi , Zahara Noor , Shetty Chirag , Weidenhammer Rachel , Watharkar Sneha , Tambvekar Pranav , Badzuh Philip P , Dias Chester , Vankayala Narendra , Kulkarni Prutha , Vallapureddy Charan , Kulkarni Shamika , Nikhare Pooja , Freese Nowlan H , Loraine Ann E 
Published: February 2022

Abstract

Summary
Rapid progress in genome science requires equally rapid visualization software development so that researchers can better explore and understand novel datasets. To make developing new visualizations faster and easier, we previously re-factored the Integrated Genome Browser (IGB), a desktop Java application with dozens of features, into a pluggable application framework that can accept new functionality as plug-ins, called IGB Apps. However, developers lacked a centralized location for sharing Apps, making it hard to connect with potential users. To fill this gap, we created an App Store for IGB, a user-friendly Web site for developers to release and document Apps, and for users to find them.

Availability and implementation
The IGB App Store is available from https://bioviz.org.
PCIG: a web-based application to explore immune–genomics interactions across cancer types
Authors: Pedrola Anna , Franch-Expósito Sebastià , Lahoz Sara , Esteban-Fabró Roger , Dienstmann Rodrigo , Bassaganyas Laia , Camps Jordi 
Published: February 2022

Abstract

Motivation
Genomic alterations can modulate the tumor immunophenotype depending on their nature and tissue of origin. Although this immune–genomic interaction may shape disease progression and response to immunotherapy, the factors governing such dynamics and the influence of each tissue-specific context remain poorly understood.

Results
Here, we have developed the PanCancer ImmunoGenomics (PCIG) tool, a web-based resource that provides researchers with the opportunity to mine immunome–genome relationships across several cancer types using data from the Pan-Cancer Analysis of Whole-Genomes (PCAWG) study, which comprises &gt;2,600 samples spanning across 20 different cancer primary sites. PCIG yields an integrative analysis of the crosstalk between somatic genomic alterations and different immune features, thus helping to understand immune response-related processes.

Availability and implementation
PCIG is freely available at https://pcig.vhio.net and is supported by all major web browsers. PCIG was developed with Django, which is a Python-based free and open-source framework, and it uses SQL Server as a relational database management system. The code is freely available for download at GitHub https://github.com/AnnaPG/PCIG and in its online supplementary material.

Supplementary information
Supplementary data are available at Bioinformatics online.
Synergies and Trade-Offs in Reducing Impacts of Unconventional Oil and Gas Development on Wildlife and Human Health
Authors: Deziel Nicole C , Shamasunder Bhavna , Pejchar Liba 
Published: February 2022

AbstractWith growing evidence of widespread health and environmental impacts from oil and gas activity, localities and states are beginning to develop protective measures. Interdisciplinary approaches that integrate across human, wildlife, domesticated animal, and land health are likely to provide more just and comprehensive solutions than would be possible with siloed approaches. However, this is not common practice, and there is little guidance on how to apply such a strategy. In the present article, we summarize the state of knowledge on the impacts of terrestrial unconventional oil and gas development from the fields of ecology and public health. We then discuss synergies and trade-offs regarding impacts and mitigation strategies emerging from these two literatures. Finally, we provide recommendations for research and practice to fill knowledge gaps and better inform integrated decision-making to achieve multiple benefits and minimize impacts on human, wildlife, domesticated animals, and land health from energy development.
Eso-Sponge® for anastomotic leakage after oesophageal resection or perforation: outcomes from a national, prospective multicentre registry
Authors: Richter Florian , Hendricks Alexander , Schniewind Bodo , Hampe Jochen , Heits Nils , von Schönfels Witigo , Reichert Benedikt , Eberle Katrin , Ellrichmann Mark , Baumann Petra , Egberts Jan-Hendrik , Becker Thomas , Schafmayer Clemens 
Published: February 2022

Abstract

Background
Anastomotic leakage (AL) after oesophagectomy and oesophageal perforations are associated with significant morbidity and mortality. Minimally invasive endoscopy is often used as first-line treatment, particularly endoluminal vacuum therapy (EVT). The aim was to assess the performance of the first commercially available endoluminal vacuum device (Eso-Sponge®) in the management of AL and perforation of the upper gastrointestinal tract (GIT).

Methods
The Eso-Sponge® registry was designed in 2014 as a prospective, observational, national, multicentre registry. Patients were recruited with either AL or perforation within the upper GIT. Data were collected with a standardized form and transferred into a web-based platform. Twenty hospitals were enrolled at the beginning of the study (registration number NCT02662777; http://www.clinicaltrials.gov). The primary endpoint was successful closure of the oesophageal defect.

Results
Eleven out of 20 centres recruited patients. A total of 102 patients were included in this interim analysis; 69 patients with AL and 33 with a perforation were treated by EVT. In the AL group, a closure of 91 per cent was observed and 76 per cent was observed in the perforation group. The occurrence of mediastinitis (P = 0.002) and the location of the defect (P = 0.008) were identified as significant predictors of defect closure.

Conclusions
The Eso-Sponge® registry offers the opportunity to collate data on EVT with a uniform, commercially available product to improve standardization. Our data show that EVT with the Eso-Sponge® is an option for the management of AL and perforation within the upper GIT.