bluuebunny/crossref_metadata_2025_split huggingface dataset:
Complete mitochondrial genome sequencing and identification of candidate genes responsible for C5-type cytoplasmic male sterility in cabbage (B. oleracea var. capitata)
Authors: Zhong Xionghui , Yue Xiangqing , Cui Jian , Han Rui , Gao Yi , Kang Jungen 
Published: September 2022

Cytoplasmic male sterility (CMS) is widely used in cruciferous vegetables hybrid breeding. The C5-type CMS cabbage line exhibits stable male sterility and offers great value for cabbage breeding. However, the underlying CMS mechanism remains unclear. Here, the complete mitochondrial genome was sequenced and assembled for this line. The genome size was 221,862 bp. Mitochondrial genome comparison showed that the mitochondrial genome was likely generated by recombination with a nap-type CMS B. napus strain. Sixty-seven unknown-function open reading frames (ORFs) were identified. Seven orfs, orf114a, orf123a, orf188a, orf222a, orf261a, orf286a, and orf322a, were specifically identified in this genome. The presence of these candidate CMS genes decreased ATPase activity and ATP content by affecting the transcript levels of energy metabolism-related genes and F1F0-ATP synthase assembly. Among them, orf188a, orf222a, orf261a, orf286a, and orf322a possessed a transmembrane structure, and orf188a was cotranscribed with rps7 and trnfM. orf222a was partially homologous to atp8 and coexpressed with nad5. orf261a and orf322a were cotranscribed with cox1 and atp9, respectively. Additionally, orf114a was cotranscribed with atp8. Yeast two-hybrid assays showed that the ORF222a protein interacts with a B. oleracea ATP17 homolog (Bo7g114140) during F0-type ATP synthase assembly, reducing the quantity and activity of assembled F1F0-ATP synthase. Cytological sections showed that premature separation of the tapetum from the connective tissue and delayed tapetal programmed cell death (PCD) might be the immediate causes of CMS in C5-type CMS cabbage lines. Our results may help uncover the molecular mechanism of C5-type CMS in B. oleracea from the perspectives of the whole mitochondrial genome and cytology of anther development.
Executive control of freestyle skiing aerials athletes in different training conditions
Authors: Li Hui , Zhang Liancheng , Wang Jingru , Liu Jie , Sun Yanlin 
Published: September 2022

IntroductionDue to the actual limitation of training conditions, the freestyle skiing aerials winter training term is short. Training tasks such as adaptability training and developing new skills are needed in summer training. When facing different training environments, freestyle skiing aerial athletes’ executive control over their abilities could be affected, which can affect their performance. Therefore, we want to research the effect of training conditions on executive control in freestyle skiing aerials athletes and its neural mechanism.Materials and methodsThirty-two freestyle skiing aerials athletes were recruited. We evaluated their executive control and used fNIRS to measure oxygenated hemoglobin concentration changes in the prefrontal cortex during a rapid event-related design go/nogo task with different training condition-activated materials.ResultsAthletes’ behavior control in the summer condition has a lower accuracy than it is in the control condition. Athletes’ behavior control in the summer and winter training conditions had a longer reaction time than that in the control condition. The activation of the bilateral dlPFC and orbitofrontal cortex had a significant main effect across training conditions when freestyle skiing aerial athletes completed executive control tasks. The activation of athletes’ bilateral vlPFC and left dlPFC had an interaction between training conditions and behavioral control.ConclusionDifferent training conditions can lead to freestyle skiing aerial athletes executive control ability to drop, players in different training conditions show less activation on both sides of the vlPFC and orbitofrontal. The bilateral vlPFC and left dlPFC have an integrated effect on behavior inhibition across training conditions.
Application of supervised machine learning algorithms to predict the risk of hidden blood loss during the perioperative period in thoracolumbar burst fracture patients complicated with neurological compromise
Authors: Yang Bo , Gao Lin , Wang Xingang , Wei Jianmin , Xia Bin , Liu Xiangwei , Zheng Peng 
Published: September 2022

BackgroundMachine learning (ML) is a type of artificial intelligence (AI) and has been utilized in clinical research and practice to construct high-performing prediction models. Hidden blood loss (HBL) is prevalent during the perioperative period of spinal treatment and might result in a poor prognosis. The aim of this study was to develop a ML-based model for identifying perioperative HBL-related risk factors in patients with thoracolumbar burst fracture (TBF).MethodsIn this study, single-central TBF patients were chosen. The medical information on patients, including clinical characteristics, laboratory indicators, and surgery-related parameters, was extracted. After comparing various ML model algorithms, we selected the best model with high performance. The model was validated using the internal validation set before performing recursive feature elimination (RFE) to determine the importance of HBL-related risk factors. The area under the receiver operating characteristic (AUC) curve, accuracy (ACC), sensitivity, and specificity were reported as critical model measures for evaluating predictive performance.ResultsIn this study, 62 (38.5%) of the 161 TBF patients were positive for HBL. There was a significant statistical difference in age, body mass index (BMI), diabetes, hypertension, Beta (percentage of vertebral restoration), duration of operation, and other pre-operative laboratory indicators between the HBL-positive and HBL-negative groups. Nine ML-based models were built and validated, with the Random Forest model having the greatest AUC in both the training set (0.905) and internal validation set (0.864). Furthermore, following RFE, age, duration of operation, Beta, pre-operative fibrinogen (Fib), and activated partial thromboplastin time (APTT) were identified as the five main important risk factors in patients with TBF during the perioperative period.ConclusionIn this study, we built and validated ML algorithms for an individualized prediction of HBL-related risk factors in the perioperative period of TBF. The importance of HBL-related risk factors could be determined, which contributes to clinicians' decision-making and improves perioperative management.
Reduction in school individualized education program (IEP) services during the COVID-19 pandemic
Authors: Chen Belinda , Rasmussen Patrick , Legg Mallory , Alexander Nicole , Vedmurthy Pooja , Asiedu Akua , Bay Mihee , Belcher Harolyn , Burton Vera Joanna , Conlon Charles , Fine Amena , Gill Ryan , Lance Eboni I. , Lipkin Paul , Wong Joyce , Wilms Floet Anna Maria , Doerrer Sarah C. , Glattfelder Jennifer , Kordek Amy , Pertman Julie , Murray Rachel , Zabel T. Andrew , Comi Anne M. , Leppert Mary L. 
Published: September 2022

PurposeThe COVID-19 pandemic created novel challenges for school systems and students, particularly students with disabilities. In the shift to remote/distance learning, this report explores the degree to which children with disabilities did not receive the special education and related services defined in their individualized education program (IEP).MethodsPatients attending an outpatient tertiary care center for neurodevelopmental disabilities in Maryland were surveyed on the impact of the pandemic on educational services provision.ResultsNearly half (46%) of respondents qualified for special education and related services through an IEP before the start of the COVID-19 pandemic. Among those with IEPs, 48% attested to reduced frequency and/or duration of special education and/or related services during the pandemic. The reduction was greatest in occupational therapy services (47%), followed physical therapy services (46%), and special education services (34%).ConclusionThis survey of children with disabilities observes a substantial reduction in IEP services reported in their completed surveys. To address the observed reduction in IEP services, we sought additional education for clinicians on the rights of students with disabilities in anticipation of students’ re-entry to the classroom. A special education law attorney provided an instructional session on compensatory education and recovery services to prepare clinicians to properly inform parents about their rights and advocate for patients with unmet IEP services during the pandemic.
Primary and albedo protons detected by the Lunar Lander Neutron and Dosimetry experiment on the lunar farside
Authors: Xu Zigong , Guo Jingnan , Wimmer-Schweingruber Robert F. , Dobynde Mikhail I. , Kühl Patrick , Khaksarighiri Salman , Zhang Shenyi 
Published: September 2022

The Lunar Lander Neutron and Dosimetry (LND) Experiment aboard the Chang’E-4 Lander on the lunar far-side measures energetic charged and neutral particles and monitors the corresponding radiation levels. During solar quiet times, galactic cosmic rays (GCRs) are the dominating component of charged particles on the lunar surface. Moreover, the interaction of GCRs with the lunar regolith also results in upward-directed albedo protons which are measured by the LND. In this work, we used calibrated LND data to study the GCR primary and albedo protons. We calculate the averaged GCR proton spectrum in the range of 9–368 MeV and the averaged albedo proton flux between 64.7 and 76.7 MeV from June 2019 (the seventh lunar day after Chang’E-4’s landing) to July 2020 (the 20th lunar day). We compare the primary proton measurements of LND with the Electron Proton Helium INstrument (EPHIN) on SOHO. The comparison shows a reasonable agreement of the GCR proton spectra among different instruments and illustrates the capability of LND. Likewise, the albedo proton measurements of LND are also comparable with measurements by the Cosmic Ray Telescope for the Effects of Radiation (CRaTER) during solar minimum. Our measurements confirm predictions from the Radiation Environment and Dose at the Moon (REDMoon) model. Finally, we provide the ratio of albedo protons to primary protons for measurements in the energy range of 64.7–76.7 MeV which confirm simulations over a broader energy range.
Halogenase-Targeted Genome Mining Leads to the Discovery of (±) Pestalachlorides A1a, A2a, and Their Atropisomers
Authors: Luo Mengna , Wang Mengyuan , Chang Shanshan , He Ning , Shan Guangzhi , Xie Yunying 
Published: September 2022

Genome mining has become an important tool for discovering new natural products and identifying the cryptic biosynthesis gene clusters. Here, we utilized the flavin-dependent halogenase GedL as the probe in combination with characteristic halogen isotope patterns to mine new halogenated secondary metabolites from our in-house fungal database. As a result, two pairs of atropisomers, pestalachlorides A1a (1a)/A1b (1b) and A2a (2a)/A2b (2b), along with known compounds pestalachloride A (3) and SB87-H (4), were identified from Pestalotiopsis rhododendri LF-19-12. A plausible biosynthetic assembly line for pestalachlorides involving a putative free-standing phenol flavin-dependent halogenase was proposed based on bioinformatics analysis. Pestalachlorides exhibited antibacterial activity against sensitive and drug-resistant S. aureus and E. faecium with MIC values ranging from 4 μg/mL to 32 μg/mL. This study indicates that halogenase-targeted genome mining is an efficient strategy for discovering halogenated compounds and their corresponding halogenases.
SELF-ALIENATION AS MANIFESTATION OF NARRATIVE STRATEGY IN THE STORY "THE PAINTER" BY TARAS SHEVCHENKO
Authors: Kovalenko K. 
Published: September 2022

The article focuses on the narrative analysis of the novel "The Painter" by T. Shevchenko in order to trace how the narrative strategy of the text contributes to the actualization of the writer's self-alienation phenomenon from his own colonized "I". The analysis is based on the system proposed by Gerard Genette: the types of narration (mimesis and diegesis) are defined, how the narration is focalized, who tells the story (types of narrators), how time is expressed in the story, how words and thoughts (discourses) are represented. The phenomenon of self-alienation is considered from the point of view of Hegel as one of the forms of alienation, as the ability of the individual in some sense to be free from their desires. As a result, they reach a higher degree of self-awareness. In the story the self-alienation expresses Taras Shevchenko's desire to distance himself from the traumatic colonial experience and isolate himself from the part of the hostile and unacceptable things in himself. He transforms his own biography unfolding before the reader a new story of redemption from serfdom: an intelligent, knowledgeable Ukrainian helps a talented young Russian artist to gain freedom. But he does not have enough strength to develop his own talent and eventually dies. In the madness and death of the Russian Shevchenko's will metaphorically appears from his colonized "I", self-alienation. The writer's use of self-irony can be traced in the written work in the humiliation and physical destruction of the former serf image. The narrative strategy of the work such as: the story on behalf of the intradiegetic homodiegetic narrator being present in the artistic world, the internal focalization of the story, the introduction of additional narrators (letters – the principle of "a text in the text"), intellectual narrative distance between the main narrator and the young artist serves as an instrument creating the phenomenon of self-alienation in the story.
Second harmonic generation in GaN transverse quasi-phase-matched waveguide pumped with femtosecond laser
Authors: Yokoyama Naoki , Morioka Yoshiki , Murata Tomotaka , Honda Hiroto , Serita Kazunori , Murakami Hironaru , Tonouchi Masayoshi , Tokita Shigeki , Ichikawa Shuhei , Fujiwara Yasufumi , Hikosaka Toshiki , Uemukai Masahiro , Tanikawa Tomoyuki , Katayama Ryuji 
Published: September 2022

Abstract
A wavelength conversion device with an input grating coupler that enables easy alignment was fabricated using a vertically polarity inverted GaN layer. The device was excited with a femtosecond laser, and a second harmonic wave with a peak wavelength of 438.4 nm was obtained. A normalized wavelength conversion efficiency of 4.7 × 10−4% W−1 and a spectral bandwidth of the second harmonic wave of 2.9 nm were comparable to the theoretical estimations taking into account serious walk-off and waveguide losses. High efficiency of 33%–34% W−1 can be expected under continuous-wave excitation.
UAV-Assisted-Smart Farming for Agricultural Monitoring in a Large Scale WSN area
Authors: Leranso Mesfin , Leng Supeng , Fakirah Maged , Salau Ayodeji Olalekan 
Published: September 2022

<p>With the aid of multiple autonomous unmanned aerial vehicles (UAVs), data collection from the large-scale Wireless Sensor Network (WSN) is a highly efficient, but challenging solution. In this paper, to minimize the total energy consumption of both UAVs, and the effective use of sink nodes' power, we optimize both the number of sink nodes and the trajectories of multiple UAVs in WSN. To do this, the UAV can start from the docking station and come back to the same dock station after the completion of the mission. To increase the lifetime WSN, we specifically use the Genetic Algorithm to choose the number of sink nodes. Then, we utilize a Deep Q-network-based method providing a Markov decision pr to establish all trajectory paths. We can show that our method can expedite the process of identifying the best answers by simulating its performance and contrasting it with other traditional heuristic benchmark techniques. </p>
Modeling Trust Relationships in Blockchain Applications: The Case of Reconfigurable Systems-on-Chip
Authors: Méré Maxime , Jouault Frédéric , Perdriau Richard , Pallardy Loïc 
Published: September 2022

<p>Nowadays, System-on-Chip (SoC) components are found everywhere in all kinds of smart devices. Each System-on-Chip contains many different blocks that provide specific functionalities, such as WiFi or Bluetooth connectivity. Whereas integrating each such block in a SoC typically requires paying some royalties, not all blocks are necessary for all applications, or throughout a device’s lifecycle. Moreover, it is not possible to manufacture a specific SoC for each application. Significant advantages are therefore expected to be gained by enabling trustworthy remote SoC reconfiguration throughout their life cycles. A few approaches attempting to address this challenge have been proposed in the literature. They are typically based on Blockchain technology in order to support decentralization without relinquishing trust. Reviewing these approaches lead us to identify a potential flaw in the proposed protocols. Indeed, a SoC should be able to trust Blockchain information that it is given, without requiring any centralization. In order to validate our suspicions, we propose in this paper to use Verifpal: a cryptographic protocol verification tool that works from textual protocol models. We use it in a slightly unorthodox way in order to model the trust relationships in one of the approaches from the literature, and to verify it. The results show that, under some assumptions, a flaw is indeed present. We propose and model several possible fixes, and present their respective limitations. </p>
Interference Mitigation for Multi-Stream Processing with Massive MIMO
Authors: Kenney Brent , Majid Arslan , Moradi Hussein , Farhang-Boroujeny Behrouz 
Published: September 2022

<p>Cyclic prefixed single carrier modulation (CP-SCM) takes the same symbol structure as the orthogonal frequency division multiplexing (OFDM). Accordingly, CP-SCM can be efficiently processed in the frequency domain for compensating channel effects and eliminating inter-symbol interference. Multi-stream processing (MSP) has recently been introduced as a resource allocation solution for CP-SCM. MSP can be implemented with a relatively small number of physical antennas while still operating in the massive MIMO regime due to the creation of virtual antennas. This paper explores another benefit of MSP: Interference Mitigation. MSP can operate in the same time domain duplexed band as interfering signals by rejecting interference at the receiver alone or coordinating with the transmitter to avoid interfered portions of the spectrum. We provide details on multiple interference mitigation techniques along with analysis and simulation results.</p>
THE RELATION BETWEEN LOSS OF A FAMILY MEMBER AND ORAL LICHEN PLANUS IN IRAQI POPULATION
Authors: Abdulrida Ferial M. 
Published: September 2022

Abstract background Oral lichen planus is common oral mucosal lesions with several predisposing factors, but with poorly identified etiology. Stressor factors could be one of etiological causes for eruption of the lesion and/or a predisposing factor for its appearance, aggravating the excited lesion. The aim of this study to evaluate certain circumstances that were passed on Iraqi population that may be related to elevated OLP incidence in Iraq. Material and method One hundred twenty-nine clinical charts for oral lichen planus patients were taken from oral pathology department college of dentistry university of Baghdad from a period 2009 to 2017. Results Fifty-eight patients only involved in the inclusion criteria of this study, the patients classified according to history associated eruption of the lesion into loss of one family member, trouble associated and both loss and trouble group .The mean age 48.37±12.2 ,the lesion most common in female than male 1.7:1,bilateral involvement of the lesion and mostly on buccal mucosa with slight higher of the red lesions over the reticular making elevated symptoms associated with the lesion mostly the burning sensation .About 65%of the patients presented within one to six months of eruption of the lesion. Conclusion The stressor events affect the age and the symptoms associated with eruption of oral lichen planus lesion.
MICROSCULPTURE EXACT DESCRIPTION OF THE SOME SPECIES OF BLISTER BEETLES (MELOIDAE) IN IRAQ
Authors: Ismail S. I. , Abdulzahra Ameer Ibrahim 
Published: September 2022

This the microsculpture of the pits on the elytron was studied for ten species of burning beetles family meloidae back to subfamilies Meloinae and Nemognathinae to show the great diversity in the shape of the pits found on the elytron in these species :Croscherichia goryi, Cerocoma graeca, Lydus mesopotamicus sp. , Lytta nitidula, Nemognatha chrysomelina, Nemognatha sp., Zonitis immaculata, Zonitis fernancastroi, Mylabris sp., Lydomorphus sp.
OEE+/A proposal for the contemporary extension of the OEE to include sustainability aspects
Authors: Fleischer Jürgen , Schlagenhauf Tobias , Netzer Markus 
Published: September 2022

Produktionsanlagen werden bislang mithilfe einer Effektivitätskennzahl bewertet und gesteuert. Eine notwendige Erweiterung der Produktionseffektivität um ein Effizienzkriterium ist bislang nicht erarbeitet, allerdings im Hinblick auf den Klimawandel unabdingbar. Dieser Beitrag stellt Shopfloor-Kennzahlen vor und gibt einen Vorschlag zur zeitgemäßen Erweiterung um Nachhaltigkeitsaspekte. Die OEE+-Kennzahl wird an einem exemplarischen Anwendungsfall bewertet.

Up to now, production plants have been evaluated and controlled with the help of an effectiveness indicator. A necessary extension of production effectiveness to include an efficiency criterion has not yet been developed, but is indispensable in view of climate change. The publication presents shopfloor ratios and gives a proposal for a contemporary extension by sustainability aspects. The OEE+ key figure is evaluated using an exemplary application.
Agile Produktionssysteme in der Batteriezellfertigung/Plant Concept for Highly Automated and Agile Calendering of Battery Electrodes
Authors: Kößler Florian , Mayer Dominik , Fleischer Jürgen 
Published: September 2022

Batteriekalander werden aktuell manuell, erfahrungsbasiert und zeitintensiv iterativ beim Start einer neuen Produktionskampagne eingestellt und bei Bedarf während der Produktion nachjustiert. Bei einer variantenreichen und agilen Produktion tritt dieser Anlaufprozess im Gegensatz zu einer auf ein Produkt spezialisierten Großserienproduktion vermehrt auf. Ein Anlagen- und Automatisierungskonzept für einen schnelleren Produktionsanlauf von Batteriekalandern wird im Folgenden vorgestellt.

Battery calenders are currently set manually, experience-based and time-intensively iteratively at the start of a new production campaign and are readjusted as required during production. In a variant-rich and agile production, this start-up process occurs more frequently in contrast to a large-scale production specialized on one product. A plant and automation concept for faster production startup of battery calenders is presented below.