bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spin supersolidity in nearly ideal easy-axis triangular quantum antiferromagnet Na2BaCo(PO4)2
Authors: Gao Yuan , Fan Yu-Chen , Li Han , Yang Fan , Zeng Xu-Tao , Sheng Xian-Lei , Zhong Ruidan , Qi Yang , Wan Yuan , Li Wei 
Published: September 2022

AbstractPrototypical models and their material incarnations are cornerstones to the understanding of quantum magnetism. Here we show theoretically that the recently synthesized magnetic compound Na2BaCo(PO4)2 (NBCP) is a rare, nearly ideal material realization of the S = 1/2 triangular-lattice antiferromagnet with significant easy-axis spin exchange anisotropy. By combining the automatic parameter searching and tensor-network simulations, we establish a microscopic model description of this material with realistic model parameters, which can not only fit well the experimental thermodynamic data but also reproduce the measured magnetization curves without further adjustment of parameters. According to the established model, the NBCP hosts a spin supersolid state that breaks both the lattice translation symmetry and the spin rotational symmetry. Such a state is a spin analog of the long-sought supersolid state, thought to exist in solid Helium and optical lattice systems, and share similar traits. The NBCP therefore represents an ideal material-based platform to explore the physics of supersolidity as well as its quantum and thermal melting.
Quantitative 3D OPT and LSFM datasets of pancreata from mice with streptozotocin-induced diabetes
Authors: Hahn Max , Nord Christoffer , van Krieken Pim P. , Berggren Per-Olof , Ilegems Erwin , Cheddad Abbas , Ahlgren Ulf 
Published: September 2022

AbstractMouse models for streptozotocin (STZ) induced diabetes probably represent the most widely used systems for preclinical diabetes research, owing to the compound’s toxic effect on pancreatic β-cells. However, a comprehensive view of pancreatic β-cell mass distribution subject to STZ administration is lacking. Previous assessments have largely relied on the extrapolation of stereological sections, which provide limited 3D-spatial and quantitative information. This data descriptor presents multiple ex vivo tomographic optical image datasets of the full β-cell mass distribution in mice subject to single high and multiple low doses of STZ administration, and in glycaemia recovered mice. The data further include information about structural features, such as individual islet β-cell volumes, spatial coordinates, and shape as well as signal intensities for both insulin and GLUT2. Together, they provide the most comprehensive anatomical record of the effects of STZ administration on the islet of Langerhans in mice. As such, this data descriptor may serve as reference material to facilitate the planning, use and (re)interpretation of this widely used disease model.
Intravital microscopy datasets examining key nephron segments of transplanted decellularized kidneys
Authors: Corridon Peter R. 
Published: September 2022

AbstractThis study contains intravital microscopy (IVM) data examining the microarchitecture of acellular kidney scaffolds. Acellular scaffolds are cell-free collagen-based matrices derived from native organs that can be used as templates for regenerative medicine applications. This data set contains in vivo assays that evaluate the effectiveness of decellularization and how these acellular nephron compartments perform in the post-transplantation environment. Qualitative and quantitative assessments of scaffold DNA concentrations, tissue fluorescence signals, and structural and functional integrities of decellularized tubular and peritubular capillary segments were acquired and compared to the native (non-transplanted) organ. Cohorts of 2–3-month-old male Sprague Dawley rats were used: non-transplanted (n = 4), transplanted day 0 (n = 4), transplanted day 1 (n = 4), transplanted day 2 (n = 4), and transplanted day 7 (n = 4). Micrographs and supporting measurements are provided to illustrate IVM processes used to perform this study and are publicly available in a data repository to assist scientific reproducibility and extend the use of this powerful imaging application to analyze other scaffold systems.

Measurements(s)
DNA quantification • tissue fluorescence • microvascular leakage • tubular and peritubular capillary integrity

Technology Type(s)
intravital microscopy • multiphoton microscopy • UV-visible spectroscopy

Sample Characterization(s)
rats • native and decellularized kidneys
Differences in acute phase response to bacterial, fungal and viral antigens in greater mouse-eared bats (Myotis myotis)
Authors: Seltmann Anne , Troxell Sara A. , Schad Julia , Fritze Marcus , Bailey Liam D. , Voigt Christian C. , Czirják Gábor Á. 
Published: September 2022

AbstractThe acute phase response (APR) is an evolutionarily well-conserved part of the innate immune defense against pathogens. However, recent studies in bats yielded surprisingly diverse results compared to previous APR studies on both vertebrate and invertebrate species. This is especially interesting due to the known role of bats as reservoirs for viruses and other intracellular pathogens, while being susceptible to extracellular microorganisms such as some bacteria and fungi. To better understand these discrepancies and the reservoir-competence of bats, we mimicked bacterial, viral and fungal infections in greater mouse-eared bats (Myotis myotis) and quantified different aspects of the APR over a two-day period. Individuals reacted most strongly to a viral (PolyI:C) and a bacterial (LPS) antigen, reflected by an increase of haptoglobin levels (LPS) and an increase of the neutrophil-to-lymphocyte-ratio (PolyI:C and LPS). We did not detect fever, leukocytosis, body mass loss, or a change in the overall functioning of the innate immunity upon challenge with any antigen. We add evidence that bats respond selectively with APR to specific pathogens and that the activation of different parts of the immune system is species-specific.
Entrance and origin of the extracranial vertebral artery found on computed tomography angiography
Authors: Yi Xueting , Xie Ping , Zhang Lianwei , Lu Fengxia , Chen Hao , Liu Kefu 
Published: September 2022

AbstractTo investigated morphological variability of vertebral artery (VA) origin and its entrance level into cervical transverse foramina by computed tomography angiography (CTA). To retrospectively investigated CTA of 223 subjects (446 VA courses). Investigated were origin of the VA and its level of entrance into vertebral transverse foramen with notification of the sex and side of variation. The VA entered the C6 transverse process in 91.70% of specimens (409 out of 446 VA courses). Abnormal entrance of VA was observed in 8.30% of specimens (37 VA courses), with the level of entrance into the C3, C4, C5, or C7 transverse foramen at 0.22%, 2.47%, 4.71% and 0.90% respectively. Comparably, the overall variability of abnormal origin of VA was 1.57% (7 out of 466 VA courses), in which the left vertebral arteries all arose from aortic arch. The variation rate of vertebral entrance rose up to 50% in abnormal origin subgroup. When comparing subgroups of subjects with normal and abnormal origin, there was significance difference in the frequency of entrance variation in the level of transverse foramen (p < 0.001). Abnormal entrance and origin of VA were observed in 8.30% and 1.57% of VA courses, which can be accurately appeared by CTA. Regarding to the subgroups of abnormal origin, the frequency of entrance variation was significantly increased in the level of transverse foramen compared to that of normal origin.
Bacillus velezensis strain Ag75 as a new multifunctional agent for biocontrol, phosphate solubilization and growth promotion in maize and soybean crops
Authors: Mosela Mirela , Andrade Galdino , Massucato Luana Rainieri , de Araújo Almeida Suelen Regina , Nogueira Alison Fernando , de Lima Filho Renato Barros , Zeffa Douglas Mariani , Mian Silas , Higashi Allan Yukio , Shimizu Gabriel Danilo , Teixeira Gustavo Manoel , Branco Kelvin Shinohata , Faria Marcos Ventura , Giacomin Renata Mussoi , Scapim Carlos Alberto , Gonçalves Leandro Simões Azeredo 
Published: September 2022

AbstractSoybean and maize are some of the main drivers of Brazilian agribusiness. However, biotic and abiotic factors are of great concern, causing huge grain yield and quality losses. Phosphorus (P) deficiency is important among the abiotic factors because most Brazilian soils have a highly P-fixing nature. Thus, large amounts of phosphate fertilizers are regularly applied to overcome the rapid precipitation of P. Searching for alternatives to improve the use of P by crops is essential to reduce the demand for P input. The use of multifunctional rhizobacteria can be considered one of these alternatives. In this sense, the objective of the present work was to select and validate bacterial strains with triple action (plant growth promoter, phosphate solubilizer, and biocontrol agent) in maize and soybean, aiming to develop a multifunctional microbial inoculant for Brazilian agriculture. Bacterial strains with high indole acetic acid (IAA) production, phosphate solubilization, and antifungal activity against soil pathogenic fungi (Rhizoctonia solani, Macrophomina phaseolina, and Fusarium solani) were selected from the maize rhizosphere. Then, they were evaluated as growth promoters in maize under greenhouse conditions. Based on this study, strain 03 (Ag75) was selected due to its high potential for increasing biomass (root and shoot) and shoot P content in maize. This strain was identified through genomic sequencing as Bacillus velezensis. In field experiments, the inoculation of this bacterium increased maize and soybean yields by 17.8 and 26.5%, respectively, compared to the control (25 kg P2O5). In addition, the inoculation results did not differ from the control with 84 kg P2O5, indicating that it is possible to reduce the application of phosphate in these crops. Thus, the Ag75 strain has great potential for developing a multifunctional microbial inoculant that combines the ability to solubilize phosphate, promote plant growth, and be a biocontrol agent for several phytopathogenic fungi.
Design, synthesis and insecticidal activity and mechanism research of Chasmanthinine derivatives
Authors: Song Ziyu , Li Xiangyu , Xu Ke , Sun Guoqing , Yang Liu , Huang Linyu , Liu Junqi , Yin Pengyuan , Huang Shuai , Gao Feng , Zhou Xianli , Chen Lin 
Published: September 2022

AbstractUnrestricted reproduction and spread of pest had caused great damage to the quality and yield of crops in recent years. Besides the use of traditional chemical pesticides, natural products also make a huge contribution against pests. Chasmanthinine, a diterpenoid alkaloid isolated from Aconitum franchetii var. villosulum, shown extremely antifeedant activity against Spodoptera exigua. Therefore, a series of novel Chasmanthinine derivatives were synthesized and their biological activity was studied in this work. Compound 33 showed the strongest antifeedant activity (EC50 = 0.10 mg/cm2) among all the test compounds. The mechanism research of 33 revealed that its antifeedant effect was related to the inhibition of carboxylesterase (CES), and proved the thiophene acyl group could form a strong binding effect with CES by molecular docking. Moreover, compound 10 exhibited the strongest cytotoxicity (IC50 = 12.87 μM) against Sf9 cell line and moderate contact toxicity. The mechanism research indicated that compound 10 could induce Sf9 cells apoptosis. In summary, the results lay a foundation for the application of diterpene alkaloids in plant protection.
Polarization-probe polarization-imaging system in near-infrared regime using a polarization grating
Authors: Sakamoto Moritsugu , Nhan Huynh Thanh , Noda Kohei , Sasaki Tomoyuki , Tanaka Masayuki , Kawatsuki Nobuhiro , Ono Hiroshi 
Published: September 2022

AbstractA polarization-probe polarization-imaging (PPPI) system was developed for the near-infrared (NIR) regime. This system comprises two components operating as a polarization generator and a polarization analyzer to enable polarization image capture under polarized light illumination. The captured polarization images contain considerable object information because the illuminating polarized light beams are affected by many of the Mueller matrix elements. By assembling the polarization camera using two liquid crystal retarders and a polarization grating, the PPPI system offers the potential to measure the Stokes parameters fully with a high extinction ratio, even in the NIR region. The PPPI system’s feasibility was demonstrated experimentally. Its dependence on the state of polarization (SoP) of the illuminating polarized light was discussed. The polarization image acquired by the PPPI system is strongly dependent on the illuminating light’s SoP, so the appropriate SoP must be selected for each object to enhance the polarization image contrast. This PPPI system should expand the range of polarization imaging applications, including LiDAR, product inspection, and bio-imaging.
Empirical analysis of the role of the environmental accountability system in energy conservation and emission reduction in China
Authors: Cui Chunying , Li Jing , Lu Zhaoying , Yan Ziwei 
Published: September 2022

AbstractMany developing countries are facing the difficulty of choosing between economic growth and energy conservation and emission reduction (ECER). China has strengthened the implementation of ECER by setting environmental accountability as the development goal of local governments, hoping to have better governance effects. To evaluate the actual intervention effect of this approach, this paper constructs panel data covering 46 countries from 1995 to 2014 and uses the difference-in-differences (DID) method and the composite control method to quantitatively analyse the policy effect. The results show that China can effectively curb energy consumption and carbon emission intensity per unit of GDP by adding ECER targets to the government’s five-year plan, which has significant effects on ECER. Furthermore, we use an intermediary mechanism to test and identify low-carbon alternatives and an ECER promotion mechanism for technological advancement. The conclusion shows that economic development is compatible with low carbon and energy consumption. Combined with China’s long-term goals for ECER, it can be considered that on the road to achieving carbon peaking and carbon neutrality in the future, the economy and tertiary industry should be rationally developed, the degree of urbanization should receive more attention, and the proportion of thermal power generation should be reduced.
Incidence of nephrotoxicity associated with intravenous colistimethate sodium administration for the treatment of multidrug-resistant gram-negative bacterial infections
Authors: Sadyrbaeva-Dolgova Svetlana , García-Fumero Ricardo , Exposito-Ruiz Manuela , Pasquau-Liaño Juan , Jiménez-Morales Alberto , Hidalgo-Tenorio Carmen 
Published: September 2022

AbstractColistimethate sodium (CMS) is the inactive prodrug of colistin, CMS has a narrow antibacterial spectrum with concentration-dependent bactericidal activity against multidrug-resistant gram-negative bacteria, including Pseudomonas aeruginosa and Acinetobacter baumannii. This study aimed to analyze potential correlations between clinical features and the development of CMS-induced nephrotoxicity. This retrospective cohort study was conducted in a tertiary-care university hospital between 1 January 2015 and 31 December 2019. A total of 163 patients received CMS therapy. 75 patients (46%) developed nephrotoxicity attributable to colistin treatment, although only 14 patients (8.6%) discontinued treatment for this reason. 95.7% of CMS were prescribed as target therapy. Acinetobacter baumannii spp. was the most commonly identified pathogen (72.4%) followed by P. aeruginosa (19.6%). Several risk factors associated with nephrotoxicity were identified, among these were age (HR 1.033, 95%CI 1.016–1.052, p < 0.001), Charlson Index (HR 1.158, 95%CI 1.0462–1.283; p = 0.005) and baseline creatinine level (HR 1.273, 95%CI 1.071–1.514, p = 0.006). In terms of in-hospital mortality, risk factors were age (HR 2.43, 95%CI 1.021–1.065, p < 0.001); Charlson Index (HR 1.274, 95%CI 1.116–1.454, p = 0.043), higher baseline creatinine levels (HR 1.391, 95%CI 1.084–1.785, p = 0.010) and nephrotoxicity due to CMS treatment (HR 5.383, 95%CI 3.126–9.276, p < 0.001). In-hospital mortality rate were higher in patients with nephrotoxicity (log rank test p < 0.001). In conclusion, the nephrotoxicity was reported in almost half of the patients. Its complex management, continuous renal dose adjustment and monitoring creatinine levels at least every 48 h leads to a high percentage of inappropriate use and treatment failure.
Investigation on pollination approaches, reproductive biology and essential oil variation during floral development in German chamomile (Matricaria chamomilla L.)
Authors: Yadav Niketa , Shakya Pooja , Kumar Ajay , Gautam Rahul Dev , Chauhan Ramesh , Kumar Dinesh , Kumar Ashok , Singh Sanatsujat , Singh Satbeer 
Published: September 2022

AbstractGerman chamomile is an important medicinal and aromatic herb known for its blue essential oil. It lacks studies on anthesis, breeding systems and floral development with their impact on the essential oil. Therefore, the study investigated floral development and divided it into six reproductive stages (RS-1 to RS-6). The first four stages (5–6 days long) were identified as the floral enlargement and differentiation, followed by the fifth stage (10 days long) of three anthesis flushes, i.e., anther dehiscence, ray and disc florets' style branches flush. Anther dehiscence started 1–2 days before style branches flushes showed protandry and overlapped later with style branches flushes. Pollen production started from RS-3 and showed maximum viability (89%) at anther dehiscence (RS-5.1). Pollen showed dispersal through the air up to 0.7 m distance. Seed setting in controlled pollination experiments showed that removing disc florets could be successfully used as the emasculation alternate in German chamomile. The maximum essential oil content (0.40%) at the full blossomed floral stage (RS-4 &-5) suggested the right time for capitula harvesting. The findings on reproductive biology and breeding systems would offer several tools and techniques to support future breeding programs for genetic improvement of German chamomile.
Effects of contoured insoles with different materials on plantar pressure offloading in diabetic elderly during gait
Authors: Shi Qiu Qiong , Li Pui Ling , Yick Kit-Lun , Li Nga-Wun , Jiao Jiao 
Published: September 2022

AbstractTo investigate the effect of contoured insoles constructed of different insole materials, including Nora Lunalastik EVA, Nora Lunalight A fresh, Pe-Lite, and PORON Medical 4708 with Langer Biomechanics longitudinal PPT arch pads on offloading plantar pressure on the foot of the elderly with Type 1 or 2 diabetes during gait. Twenty-two elderly with Type 1 or 2 diabetes participated in the study. Their plantar pressure was measured by using an insole measurement system, while the participants walked 10 m in their bare feet or used each experimental insole in random order. The plantar surface was divided into four specific regions including the toes, forefoot, midfoot, and rearfoot. The mean peak pressure (MPP) and pressure–time integral (PTI) of ten steps with or without wearing one of the four insoles were analyzed on the dominant foot and the four specific plantar regions. After completion of the activities, the participants scored each insole from 1 (the least comfortable) to 10 (the most comfortable). The analysis of variance (ANOVA) factor of the insoles had significant effects on the MPP (P < 0.001) and PTI (P = 0.004) in the dominant foot during gait. Pairwise comparison results showed that the MPP and PTI in the dominant foot were significantly lower (P < 0.001) with PORON Medical 4708 than barefoot, Nora Lunalight A fresh, and Pe-Lite. Additionally, the insole materials had a significant effect for the forefoot (P < 0.001) and rearfoot (P < 0.001) in terms of the MPP and PTI compared with the barefoot condition during gait. Regardless of the plantar region, the MPP and PTI values were the lowest when PORON Medical 4708 was used as the insole material among four insole materials. Meanwhile, a significantly lower MPP and PTI can be found in the forefoot and rearfoot with the use of the four experimental insoles when compared with barefoot. The soft insole materials (i.e., PORON medical 4708 and Nora Lunalastik EVA) had a better performance than the rigid insole materials (i.e., Nora Lunalight A fresh, and Pe-Lite) on plantar pressure offloading for diabetic elderly.
Design of a phased array antenna with scan loss reduction and gain enhancement by using reconfigurable subarrays
Authors: Chu Hui , Shao Chuan , Zhu Xiaohua , Guo Yong‐Xin 
Published: September 2022

AbstractIn order to reduce the scan loss and also obtain higher scanning gain for a phased array, a subarray design is proposed in this study. Different from the prior works, the number of active phase shifters utilised in this topology is identical to its counterpart without subarrays, which makes it more cost‐effective. To achieve this valuable characteristic, a reconfigurable beam‐former is proposed to enable the radiation pattern of a subarray to be switchable to different modes for different scanning regions. The proposed beam‐former is based on substrate‐integrated waveguide (SIW) and featured by extremely low‐loss, due to its unique working mechanism. For validation, a fully integrated subarray module consisting of a beam‐former and two Yagi‐Uda antennas is designed and analysed. Furthermore, in order to show the effectiveness, five subarray modules with uniform spacing are utilised to construct a complete prototype operating at 15 GHz. Measurement results of the entire array indicate that the achieved gain is 2∼3 dB higher than its counterpart without the subarray, from −45° to +45° in the beam‐scanning plane. Meanwhile, the scan loss is decreased from ±1.45 dB to smaller than ±0.9 dB. Meanwhile, sidelobe levels are also improved for scanning angles between ±45°. It should be pointed out that the proposed approach is also applicable to broaden the scanning angle of phased arrays with properly selected antenna elements. Since there is no need to increase the number of active phase shifters, this subarray‐based approach can be considered more economic, and is very attractive for a variety of phased array systems.