bluuebunny/crossref_metadata_2025_split huggingface dataset:
Personalized values in life as point of interaction with the world: Developmental/neurobehavioral basis and implications for psychiatry
Authors: Kasai Kiyoto , Yagishita Sho , Tanaka Saori C. , Koike Shinsuke , Murai Toshiya , Nishida Atsushi , Yamasaki Syudo , Ando Shuntaro , Kawakami Norito , Kanehara Akiko , Morita Kentaro , Kumakura Yousuke , Takahashi Yusuke , Sawai Yutaka , Uno Akito , Sakakibara Eisuke , Okada Naohiro , Okamoto Yasumasa , Nochi Masahiro , Kumagaya Shin‐ichiro , Fukuda Masato 
Published: June 2022

AbstractBehavioral neuroscience has dealt with short‐term decision making but has not defined either daily or longer‐term life actions. The individual brain interacts with the society/world, but where that point of action is and how it interacts has never been an explicit scientific question. Here, we redefine value as an intrapersonal driver of medium‐ and long‐term life actions. Value has the following three aspects. The first is value as a driving force of action, a factor that commits people to take default‐mode or intrinsic actions daily and longer term. It consists of value memories based on past experiences, and a sense of values, the source of choosing actions under uncertain circumstances. It is also a multilayered structure of unconscious/automatic and conscious/self‐controlled. The second is personalized value, which focuses not only on the value of human beings in general, but on the aspect that is individualized and personalized, which is the foundation of diversity in society. Third, the value is developed through the life course. It is necessary to clarify how values are personalized through the internalization of parent–child, peer, and social experiences through adolescence, a life stage almost neglected in neuroscience. This viewpoint describes the brain and the behavioral basis of adolescence in which the value and its personalization occur, and the importance of this personalized value as a point of interaction between the individual brain and the world. Then the significance of personalized values in psychiatry is discussed, and the concept of values‐informed psychiatry is proposed.
Predicting peer acceptance and peer rejection for autistic children
Authors: Feldman Melanie , Hamsho Narmene , Blacher Jan , Carter Alice S. , Eisenhower Abbey 
Published: June 2022

AbstractAutistic students often experience peer relationship difficulties. As peer acceptance and rejection may be malleable over time, we examined predictors of change in peer acceptance and peer rejection among early elementary‐age autistic students. We followed 166 autistic children (mean age: 6.1 years [range: 4–8], 82.5% boys, grades preK‐2nd) longitudinally across 2 school years. Social skills, internalizing problems, and externalizing behaviors were considered as predictors of change in teacher‐rated peer acceptance and rejection, covarying IQ and autism characteristics. Autistic children experienced high rejection and low acceptance; 51.9% of children were rejected by peers in one or both school years. Results revealed distinct predictors for peer acceptance versus rejection: social skills predicted change in peer acceptance across school years, whereas externalizing problems predicted change in peer rejection. Internalizing problems did not predict change in either construct. Findings can assist school professionals in supporting social acceptance and acceptance for young autistic students.
The role of high school student engagement in postsecondary enrollment
Authors: Fraysier Kathleen , Reschly Amy L. 
Published: June 2022

AbstractThe purpose of this study was to examine whether secondary student engagement was predictive of college attendance. Data were drawn from the High School Longitudinal Study of 2009 9th grade (n = 21,444) and 11th grade (n = 20,549) cohorts. Multilevel modeling was used to analyze whether demographic, academic, financial, and engagement variables predicted postsecondary enrollment. Demographic (higher SES, attending a Catholic or private school) and academic (English and Math GPA) variables were predictive of college enrollment across both cohorts, as were participants' thoughts on the affordability of college. For ninth grade students, the engagement scales of family support for learning and future goals and aspirations remained significant predictors of enrollment after accounting for other variables. Among 11th grade students, peer support for learning, future goals and aspirations, and behavioral engagement remained significant predictors of enrollment. Student engagement is thought to underlie high school and college completion efforts but little research connects these levels of schooling. This study suggests providing support for students' engagement in high school could positively affect college enrollment. Financial education about the costs and options for paying for college may also be beneficial.
Proteomic analysis reveals stage‐specific reprogramed metabolism for the primary breast cancer cell lines MGSO‐3 and MACL‐1
Authors: Braga Fabio Henrique Guimarães , Gómez‐Mendoza Diana Paola , Lemos Rafael Pereira , Rodrigues‐Ribeiro Lucas , Raíssa‐Oliveira Brenda , Rodrigues Andréia Laura Prates , Gorshkov Vladimir , Kjeldsen Frank , Cruz Jader Santos , Verano‐Braga Thiago 
Published: June 2022

AbstractBreast cancer is the most prevalent cancer in women worldwide. Its molecular subtypes are based on the presence/absence of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). MACL‐1 and MGSO‐3 are cell lines derived from primary tumor sites of patients diagnosed with luminal A subtype carcinoma (ER+/PR+/HER2−) and ductal carcinoma in situ (ER−/PR−/HER2+), respectively. However, these cell lines lost the expression of these markers over cell culturing, and both have triple‐negative phenotypes (ER−/PR−/HER2−), which has the poorest prognosis. Here, we sought to study the proteome signature of MGSO‐3 and MACL‐1, comparing them with the epithelial cell line MCF‐10A and the well‐established metastatic‐derived breast cancer cell line MDA‐MB‐231. Our results showed that proteins associated with the tricarboxylic acid cycle (TCA) and oxidative phosphorylation (OXPHOS) were upregulated in MGSO‐3 and MACL‐1 cells. These cell lines also showed upregulation of pro‐apoptotic proteins when compared with MDA‐MB‐231. The molecular differences highlighted in this study may clarify the molecular basis behind cancer cells functioning and may reveal novel signatures across the breast cancer cell models.
Psychosocial characteristics of chronic pain in cancer survivors referred to an Australian multidisciplinary pain clinic
Authors: Glare Paul A. , Costa Daniel J. , Nicholas Michael K. 
Published: June 2022

AbstractObjectiveTo describe the clinical and psychosocial characteristics of chronic pain in cancer survivors referred to one Australian hospital's ambulatory pain clinic over a 7‐year period (2013‐19), and to compare cancer treatment‐related pain with comorbid non‐malignant pain.MethodRetrospective chart review including responses to standardized self‐report questionnaires (Brief Pain Inventory, Depression Anxiety Stress Scale, Pain Self‐Efficacy Questionnaire, Pain Catastrophizing Scale), routinely collected in all patients referred to pain clinics at Australian and New Zealand hospitals.ResultsOf 3510 new referrals during the study period, 267 (7.5%) had a history of cancer and 176 (5.0%) met the study's eligibility criteria. Their average age was 63 ± 13 years, with 55% female. Breast cancer survivors were commonest, followed by hematological, prostate, melanoma, and colorectal, a median of 3 years post‐diagnosis. Pain was attributed to cancer treatment in 87 (49%), surgery being the commonest modality. Multimodal treatment (n = 89, 58%) was significantly commoner in the treatment‐related pain group (p < 0.001). Average pain severity was moderate, as was pain‐related disability and distress. Pain cognitions were often maladaptive (low pain self‐efficacy, high pain catastrophizing), predicted by pre‐existing anxiety and depression. Associations between pain cognitions and outcomes were medium‐to‐large. Differences between treatment pain and comorbid pain were small‐to‐medium. Their scores were similar to Australian pain clinic norms.ConclusionCancer treatment causes tissue damage, but pain‐related distress and disability in survivors is associated with maladaptive pain cognitions. Survivors with poor pain outcomes should be evaluated for unhelpful thoughts and beliefs especially when they have pre‐existing depression or anxiety.
Recent insights into SARS‐CoV‐2 omicron variant
Authors: Silva Severino Jefferson Ribeiro da , Kohl Alain , Pena Lindomar , Pardee Keith 
Published: June 2022

AbstractThe SARS‐CoV‐2 omicron variant (B.1.1.529) was first identified in Botswana and South Africa, and its emergence has been associated with a steep increase in the number of SARS‐CoV‐2 infections. The omicron variant has subsequently spread very rapidly across the world, resulting in the World Health Organization classification as a variant of concern on 26 November 2021. Since its emergence, great efforts have been made by research groups around the world that have rapidly responded to fill our gaps in knowledge for this novel variant. A growing body of data has demonstrated that the omicron variant shows high transmissibility, robust binding to human angiotensin‐converting enzyme 2 receptor, attenuated viral replication, and causes less severe disease in COVID‐19 patients. Further, the variant has high environmental stability, high resistance against most therapeutic antibodies, and partial escape neutralisation by antibodies from convalescent patients or vaccinated individuals. With the pandemic ongoing, there is a need for the distillation of literature from primary research into an accessible format for the community. In this review, we summarise the key discoveries related to the SARS‐CoV‐2 omicron variant, highlighting the gaps in knowledge that guide the field's ongoing and future work.
Constructing Reactive Micro‐Environment in Basal Plane of MoS2 for pH‐Universal Hydrogen Evolution Catalysis
Authors: Koudakan Payam Ahmadian , Wei Cong , Mosallanezhad Amirabbas , Liu Bo , Fang Yanyan , Hao Xiaobin , Qian Yitai , Wang Gongming 
Published: June 2022

AbstractMoS2 represents a promising catalyst for the hydrogen evolution reaction (HER) in water splitting, but the inefficient catalytic activity in a pH‐universal environment is an obstacle to developing practical applications. Boosting and balancing the water dissociation and hydrogen desorption kinetics is crucial in designing high‐performance catalysts for the overall pH range. Herein, it is experimentally demonstrated that cobalt single‐atom doping can effectively construct a reactive CoMoS micro‐environment on the basal plane of MoS2 and thus alter the uniformity of surface electron density, which is further confirmed by the theoretical results. The reactive micro‐environment consisting of single‐atom Co with the surrounding Mo and S atoms possesses excellent water dissociation and hydrogen desorption kinetics, exhibiting a superior performance of 36 mV at 10 mA cm−2 with a Tafel slope of 33 mV dec−1 in the alkaline condition. Meanwhile, it also shows worthy activity in the acidic (97 mV) and neutral (117 mV) environments. This work provides a facile strategy to improve the HER catalysis of MoS2 in pH‐universal environments.
Knowledge chain integration of design structure matrix‐based project team: An integration model
Authors: Tian Shuo , Zhao Hangeng , Xu Xiaobo , Mu Rongchao , Ma Qiang 
Published: June 2022

AbstractBased on the project team's knowledge activities in the knowledge chain, we analyse the knowledge management, develop a design structure matrix (DSM) model, and utilize the AIDER clustering to solve the cooperation problems caused by team members from different departments. By analysing the coupling relationship between team members' knowledge chains and clustering the knowledge activities with a high coupling degree, the project team's knowledge chain achieves integration. Finally, plugging the proposed method into a business case shows that the method can improve the project team's knowledge management performance.
Valorization of Potato Peels Starch for Efficient β‐Cyclodextrin Production and Purification through an Eco‐Friendly Process
Authors: Ben Amara Fakhreddine , Bouzid Moetaz , Sahnoun Mouna , Ben Nasr Yosri , Jaouadi Bassem , Bejar Samir , Jemli Sonia 
Published: June 2022

AbstractPotato peels (PP) are agro‐industrial co‐products generated in huge quantities by the potato processing industry. Obtaining value‐added products from PP is a current research challenge. As cyclic oligosaccharides is produced from starch by the action of cyclodextrin glucanotransferase (CGTase), β‐cyclodextrins (β‐CDs) are increasingly used in various industrial applications. In an attempt to develop a low‐cost process for β‐CDs production, starch is firstly extracted from PP. The productions of the US132 CGTase and β‐CDs are then optimized via experimental designs. The US132 CGTase production from the recombinant T7 express Escherichia coli strain is enhanced 20‐fold to reach 59.95 U mL−1. Subsequently, the β‐CDs production by the US132 CGTase is optimized to reach a high level (67.26 g L−1). The β‐CDs are then purified to homogeneity through a simple eco‐friendly crystallization method that provided a purification yield of 20%. This study reveals that β‐CDs production from valorized starch is a promising strategy used to valorize PP and minimize β‐CDs production cost.
Atomically dispersed dual‐metal‐site PGM‐free electrocatalysts for oxygen reduction reaction: Opportunities and challenges
Authors: Yang Xiaoxuan , Priest Cameron , Hou Yang , Wu Gang 
Published: June 2022

AbstractAtomically dispersed and nitrogen coordinated single metal site (MNx, M = Fe, Co, or Mn) moieties embedded in partially graphitized carbon (denoted as M–N–C) are recognized as the most promising platinum group metal‐free catalysts for the oxygen reduction reaction (ORR) in proton exchange membrane fuel cells. However, simply regulating their coordination environments and local structures of single metal sites cannot fundamentally change active site structure, which leads to insufficient activity and stability. A second transition metal can be incorporated to design dual‐metal sites, offering a new opportunity to modulate the electronic and geometric structures of M–N–C catalysts. Therefore, exploring optimal atomically dispersed dual‐metal‐site is essential to designing new active sites with enhanced ORR activity, and stability, especially breaking the activity‐stability trade‐off. This review provides a comprehensive analysis of the advances in developing atomically dispersed dual‐metal site catalysts for the ORR, including innovative synthesis methods, primary structural configurations, and the mechanisms to promote catalytic performance. We aim to elucidate the crucial structure–property correlation, emphasizing the inherent electronic and geometric effects of dual metal sites. Finally, we discuss the current challenges of dual‐metal site catalysts concerning rational design, precise synthesis, and high‐fidelity structural characterization.
Fe‐based catalysts for nitrogen reduction toward ammonia electrosynthesis under ambient conditions
Authors: Zhu Haiding , Ren Xuefeng , Yang Xiaoxuan , Liang Xingyou , Liu Anmin , Wu Gang 
Published: June 2022

AbstractAs one of the most important chemicals and carbon‐free energy carriers, ammonia (NH3) has significant energy‐related applications in industry and agriculture. Ninety percent of NH3 is produced by the Haber–Bosch process using high‐purity N2 and H2 at high temperatures and pressures, which consumes about 1% of the total energy production and causes 1.4% of global CO2 emissions. The environmentally friendly electrochemical nitrogen reduction reaction (NRR) with low energy consumption is a promising alternative to the conventional Haber–Bosch process. However, the main issue is the low Faradaic efficiency and NH3 selectivity of electrochemical NRR, caused by inert nitrogen molecules and competitive hydrogen evolution reaction. As one of the cheapest and most abundant transition metals widely utilized in the Haber–Bosch process, the Fe element has presented the potential high performance for the electrochemical NRR. This article summarizes recent advances and research progress in non‐noble Fe‐based catalysts used for NH3 electrosynthesis. Various synthetic protocols, structure/morphology modification, performance improvement, and reaction mechanisms are comprehensively presented. Based on recent experimental and theoretical studies, we aim to illuminate the structure–property relationship and offer an excellent opportunity for engineering advanced Fe‐based catalysts for nitrogen fixation. The most critical challenges and opportunities for Fe‐based catalysts are also provided. This review would open up a promising avenue toward developing platinum‐group‐metal‐free catalysts for electrochemical NRR applications in the future.
Rational design of Ruddlesden–Popper perovskite electrocatalyst for oxygen reduction to hydrogen peroxide
Authors: Han Ning , Feng Shihui , Guo Wei , Mora Omar Martinez , Zhao Xiaolin , Zhang Wei , Xie Sijie , Zhou Zhenyu , Liu Zhiwei , Liu Qiong , Wan Kai , Zhang Xuan , Fransaer Jan 
Published: June 2022

AbstractAlthough the oxygen reduction process to hydrogen peroxide (H2O2) is a green option for H2O2 generation, the low activity and selectivity hindered the industry's process. In recent years, the electrochemical synthesis of H2O2 through a 2e– transfer method of oxygen reduction reaction (ORR) has piqued the interest of both academics and industry. Metal oxide catalysts have emerged as a novel family of electrochemical catalysts due to their unusual physical, chemical, and electrical characteristics. In this work, we first developed a Ruddlesden–Popper perovskite oxide (Pr2NiO4+δ) as a highly selective and active catalyst for 2e– ORR to produce H2O2. Molybdenum was introduced here to adjust the oxidation states of these transition metals with successful substitution into Ni‐site to prepare Pr2Ni1‐xMoxO4+δ, and the molybdenum substitution improves the H2O2 selectivity during the ORR process, in 0.1 M KOH, from 60% of Pr2NiO4+δ to 79% of Pr2Ni0.8Mo0.2O4+δ at 0.55 V versus RHE. A limiting H2O2 concentration of 0.24 mM for Pr2NiO4+δ and 0.42 mM for Pr2Ni0.8Mo0.2O4+δ was obtained at a constant current of 10 mA/cm2 using a flow‐cell reactor using a gas‐diffusion electrode.
Hydrodynamic characteristics and application of tuned liquid dampers with internal damping devices
Authors: Zhang Lanfang , Zhang Lele , Xie Zhuangning 
Published: June 2022

SummaryThe hydrodynamic characteristics of rectangular tanks with internal damping devices, including baffles and paddles, are investigated using shaking table tests excited by colored noise. The complex second‐order blind identification method is employed to decouple fluid sloshing responses and to obtain mode shapes. The modal frequency and damping ratio are also identified by the modified Bayesian spectral density approach. The influence of baffle angle, paddle width, liquid depth, and excitation amplitude on the natural frequency and damping ratio of tuned liquid dampers (TLDs) is analyzed. Results show that the natural frequency is reduced due to the added mass produced by the damping devices, and the reduction increases gradually with the increase in the size of the damping devices, indicating that the influence of the added mass should be considered in the design. This result is essentially different from the conclusion of the existing finding that the modal frequency of TLD increases continuously with the increase in the baffle angle. Therefore, the tuning of TLD cannot be realized by rotating the baffles. Moreover, the damping ratio of TLD with paddles shows a nonlinear relationship with the fluid response. The nonlinear empirical model fitted by the test results can predict the damping ratio with high accuracy and can be used in the preliminary design of TLD for the wind‐induced vibration control of super‐tall buildings.
The effectiveness and limitations of digital images for taxonomic research
Authors: Phang Aireen , Atkins Hannah , Wilkie Peter 
Published: June 2022

AbstractIn response to the worldwide coronavirus outbreak, which effectively shut down fieldwork, laboratory and herbarium‐based studies, an evaluation was made of the effectiveness and limitations of undertaking a virtual taxonomic study using only online herbarium specimen resources related to the genus Madhuca (Sapotaceae) for the Flora of Singapore. The study demonstrated the immense value of digital images to basic taxonomic research but also found that diagnostic micro‐morphological characters, often critical in defining species boundaries, cannot be seen in many digital images, even at high resolution. Several recommendations are made on how to maximise the utility of online herbarium specimen images to help facilitate future taxonomic research, though it is clear that physical access to herbarium specimens remains essential.
Co‐exposure of iron oxide nanoparticles and glyphosate‐based herbicide promote liver toxicity in guppy (Poecilia reticulata): A histochemical and ultrastructural approach
Authors: Martins Lunara Kênida Lessa , Lima‐Faria João Marcos de , Guimarães Lucas Nunes , Silva Victória Costa da , Moreira Paulo Cesar , Sabóia‐Morais Simone Maria Teixeira de 
Published: June 2022

AbstractCitrate functionalized iron oxide nanoparticles (IONPs) are employed for various purposes‐including environmental remediation but the interaction of IONPs with aquatic contaminants is poorly understood. Among those, glyphosate‐based herbicides are toxic and affect target organs such as the liver. Evaluations of livers of female Poecilia reticulata by exposures to IONPs at a concentration of 0.3 mg/L were performed with association to: (1) 0.65 mg of glyphosate per litter and (2) 1.3 mg of glyphosate per litter of Roundup Original, and (3) glyphosate P.A at 0.65 mg/L. These associations were carried out progressively, after 7, 14, and 21 days. We detected circulatory disturbances, inflammatory responses, activation of the immune system, regressive changes, and progressive responses with changes in the connective tissue and decreased glycogen reserve from days 14 to 21. Ultrastructural changes in the Disse space and microvilli of hepatocytes indicated decreased contact surface area. In general, the damage was time and concentration dependent, increasing from 7 to 14 days and tending to stabilize from 14 to 21 days. Therefore, herbicide‐associated IONPs functioned as xenobiotics inducing intense cellular detoxification processes and activation of hepatic immune responses.