bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dose–response association between maternal pre-pregnancy bodyweight and gestational diabetes mellitus following ART treatment: a population-based cohort study
Authors: Xiong Yiquan , Wang Jing , Qi Yana , Liu Chunrong , Li Mingxi , Yao Guanhua , Sun Wei , Qian Yongyao , Ye Lishan , Liu Hui , Xu Qiushi , Zou Kang , Tan Jing , Sun Xin 
Published: June 2022

AbstractBackgroundThe impact of maternal pre-pregnancy bodyweight on gestational diabetes mellitus (GDM) following assisted reproductive technology (ART) treatment has been insufficiently investigated. The aim of this study was to investigate the association between maternal pre-pregnancy bodyweight and GDM following ART.MethodsFrom January 2014 to March 2019, this population-based retrospective cohort study included pregnancies achieved by ART treatment in a pregnancy registration database in China. Multivariate regression analysis and restricted cubic splines were used to explore the association between bodyweight and GDM.ResultsA total of 6,598 pregnancies were included. The incidence of GDM was 26.0% (1715/6598). A total of 868 (13.2%) pregnant women were underweight, 665 (10.8%) were overweight, and 145 (2.20%) were obesity. We found a linear dose–response relation between maternal body mass index and GDM by restricted cubic splines, where one unit body mass index increase was associated with the 15% elevated risk of GDM (adjusted odds ratio [OR] 1.15, 95% CI 1.08–1.22). Compared to the normal weight group, maternal underweight was associated with lower risk of GDM (adjusted OR 0.68, 95% CI 0.57–0.82), while increased risk was found for overweight (adjusted OR 1.54 95% CI 1.29–1.84) and obesity (adjusted OR 1.74, 95% CI 1.23–2.47).ConclusionsOur study found a linear dose–effect relationship between pre-pregnancy bodyweight and GDM following ART treatment. The findings in this study support the clinical recommendation of advising women with overweight or obesity to lose weight prior to ART treatment.
Spatial variations in family planning demand to limit childbearing and the demand satisfied with modern methods in sub-Saharan Africa
Authors: Olakunde Babayemi O. , Pharr Jennifer R. , Adeyinka Daniel A. , Chien Lung-Chang , Benfield Rebecca D. , Sy Francisco S. 
Published: June 2022

Abstract
Background
There is an increasing demand for family planning to limit childbearing in sub-Saharan Africa (SSA). However, limited studies have quantified the spatial variations. This study examined: (i) the spatial patterns in the demand for family planning to limit childbearing and satisfied with modern methods, and (ii) the correlates of the demand for family planning to limit childbearing satisfied with modern methods in SSA.

Methods
This study analyzed secondary data on 306,080 married/in-union women obtained from Demographic Health Surveys conducted between 2010 and 2019 in 33 sub-Saharan African countries. We conducted exploratory spatial data analysis, with countries as the unit of analysis. We also performed regression analysis to determine the factors associated with demand for family planning to limit childbearing satisfied with modern methods in SSA.

Results
The mean percentage of women who demanded for family planning to limit childbearing by country was 20.5% while the mean prevalence of demand for family planning to limit childbearing satisfied with modern methods by country was 46.5%. There was a significant positive global spatial autocorrelation in the demand for family planning to limit childbearing (global Moran’s I = 0.3, p = 0.001). The cluster map showed the concentration of cold spots (low–low clusters) in western and central Africa (WCA), while hot spots (high–high clusters) were concentrated in eastern and southern Africa (ESA). Also, the demand for family planning to limit childbearing satisfied with modern methods showed significant positive global spatial autocorrelation (global Moran’s I = 0.2, p = 0.004) and concentration of cold spots in WCA. In the final multivariable regression model the joint family planning decision making (β = 0.34, p < 0.001), and antenatal care (β = 13.98, p < 0.001) were the significant factors associated with the demand for family planning to limit childbearing satisfied by modern methods.

Conclusions
There are significant spatial variations in the demand for family planning to limit childbearing and the demand satisfied by modern methods, with cold spots concentrated in WCA. Promoting joint decision making by partners and increasing uptake of antenatal care may improve the demand for family planning to limit childbearing satisfied with modern methods.
Current global status, subtype distribution and zoonotic significance of Blastocystis in dogs and cats: a systematic review and meta-analysis
Authors: Shams Morteza , Shamsi Laya , Yousefi Amirhosein , Sadrebazzaz Alireza , Asghari Ali , Mohammadi-Ghalehbin Behnam , Shahabi Saeed , Hatam Gholamreza 
Published: June 2022

Abstract
Background
Blastocystis is a common intestinal protozoa found in animal and human fecal samples, with over 1 billion individuals infected worldwide. Since domestication, dogs and cats have had a close bond with humans. However, their close proximity poses a potential health risk since they may harbor several zoonotic agents. A global estimate of Blastocystis infection and subtype (ST) distribution in dogs and cats would therefore be of great health importance to humans.

Methods
We performed a comprehensive systematic search of four English-language databases (PubMed, Scopus, Google Scholar, Web of Science) for relevant articles up to 8 November 2021. The random-effects model was used to make pooled estimates with confidence intervals (CIs).

Results
In total, we identified 49 publications that met our inclusion criteria and subsequently analyzed the 65 datasets in these articles, of which 23 and 42 datasets were on cats and dogs, respectively. Among the 2934 cats included in the 23 datasets, which involved 16 countries, the prevalence rate of Blastocystis infection was 9.3% (95% CI 5.3–15.9%). The prevalence of Blastocystis infection was slightly lower [7%, 95% CI 4.7–10.4%) among the 7946 dogs included in the 42 datasets, involving 23 countries. The sensitivity analysis showed that no remarkable variation in the estimates upon the stepwise removal of each dataset. Higher ST diversity was found among the examined dogs (ST1-8, ST10, ST23, ST24) than among cats (ST1-4, ST10, ST14). Among dogs, ST3 was the most frequent ST (41.3%), followed by ST2 (39.3%), ST1 (30.9%), ST4 (13.4%), ST8 (12.7%), ST10 (11%) and ST5 (8.1%). Also among dogs, each of ST6, ST7, ST23 and ST24 was observed in only one study. Of the ST found in the cats examined, ST4 (29.5%), followed by ST10 (22.5%), ST1 (19.8%) and ST3 (17.6%) were the most common. A single study also reported the presence of both ST2 and ST14 in cats. With respect to zoonotic Blastocystis STs (ST1–ST9 and ST12), eight were reported from dogs (ST1-ST8) and four were isolated from cats (ST1–ST4), showing the implication of dog and cats in zoonotic transmission.

Conclusions
Taken together, our results show that elucidation of the true epidemiology and ST distribution of Blastocystis in dogs and cats demands more comprehensive studies, particularly in the negelected regions of the world.

Graphical Abstract
Anticipated reactions to learning Alzheimer’s disease biomarker results
Authors: Clark Lindsay R. , Erickson Claire M. , Jonaitis Erin M. , Ma Yue , Chin Nathaniel A. , Basche Kristin , Ketchum Frederick B. , Gleason Carey E. 
Published: June 2022

Abstract

Introduction
We developed the Alzheimer’s Biomarker Survey to assess willingness to enroll in biomarker studies that disclose results and anticipated reactions to an elevated biomarker result.

Methods
Participants included cognitively unimpaired adults enrolled in longitudinal AD studies (n = 334, mean age = 64.8 ± 7.7, 44% non-Hispanic Black or African American). Exploratory and confirmatory factor analyses determined the latent structure comprising anticipated reactions to learning AD biomarker results. Measurement invariance was tested across racial groups.

Results
Two models comprising behavior change and psychological impact fit well for the total sample and the two racial groups. The 2-factor behavior change model assessed constructs of planning and dementia risk-reduction. The 3-factor psychological impact model assessed constructs of distress, cognitive symptoms, and stigma. Both models exhibited measurement invariance across racial groups.

Discussion
The 28-item Anticipated Reactions to AD Biomarker Disclosure scale is a reliable and valid measure of anticipated reactions when communicating AD biomarker results to research participants.
An experimental study of group-by and aggregation on CPU-GPU processors
Authors: Luan Hua , Chang Lei 
Published: June 2022

AbstractHash-based group-by and aggregation is a fundamental operator in database systems. Modern discrete GPUs (graphics processing units) have been considered to accelerate the performance. However, the data transfer through the PCIe (peripheral component interconnect express) bus would reduce gains. On recent architectures, the GPU and the CPU (central processing unit) are built into the same chip which removes the data transmission and offers new performance opportunities. Yet there has been no systematic analysis of grouping and aggregation algorithms on such architectures. In this paper, we study the behaviors of various hash-based grouping and aggregation methods on coupled architectures to provide meaningful guidelines. We conduct an extensive experimental study and analysis on the single CPU, the coupled GPU, and both processors. Six dimensions are considered in analyzing the hashing methods carefully: (1) hashing scheme, (2) hash function, (3) data size, (4) group cardinality, (5) load factor, and (6) data distribution. Two additional dimensions are also explored: (7) shared and independent hash tables and (8) running on single processors and co-processing. We hope the results in our study could help database researchers to choose the right direction in terms of algorithm design and system optimization.
Coupling function from bath density of states
Authors: Nemati S. , Henkel C. , Anders J. 
Published: June 2022

Abstract
Modelling of an open quantum system requires knowledge of parameters that specify how it couples to its environment. However, beyond relaxation rates, realistic parameters for specific environments and materials are rarely known. Here we present a method of inferring the coupling between a generic system and its bosonic (e.g., phononic) environment from the experimentally measurable density of states (DOS). With it we confirm that the DOS of the well-known Debye model for three-dimensional solids is physically equivalent to choosing an Ohmic bath. We further match a real phonon DOS to a series of Lorentzian coupling functions, allowing us to determine coupling parameters for gold, yttrium iron garnet (YIG) and iron as examples. The results illustrate how to obtain material-specific dynamical properties, such as memory kernels. The proposed method opens the door to more accurate modelling of relaxation dynamics, for example for phonon-dominated spin damping in magnetic materials.
Equivalent synchronization patterns in chaotic jerk systems
Authors: Mirzaei Simin , Parastesh Fatemeh , Jafari Sajad , Schöll Eckehard , Kurths Jürgen 
Published: June 2022

AbstractJerk systems are some of the simplest dynamical systems that can exhibit chaotic dynamics. This paper investigates the synchronization of coupled jerk systems with coupling in single variables. We apply the well-known approach for synchronization analysis, the master stability function, which determines the stability of the synchronization manifold. It is shown that a jerk system in which the jerk equation is not dependent on the acceleration has similar master stability functions when coupled in velocity or acceleration variables. Therefore, the system has the same synchronization behavior in these two coupling configurations. Such an equivalence has not been reported in the literature.
Fluctuation-dissipation theorem with Loewner time
Authors: Shibasaki Yusuke 
Published: June 2022

Abstract
Although the fluctuation-dissipation theorem (FDT) is recognized as a general result of statistical physics, its applicability to the non-equilibrium and nonlinear system has not been completely clarified. In this study, we observe that introducing a new type of time coordinate determined by the stochastic Loewner evolution enables the conversion of a certain class of nonlinear Langevin equations into linear ones. The formulation using Loewner time yields a linear response function for the nonlinear systems under a small perturbation. The proposed approach is expected to provide an extension of the conventional FDT in a form applicable to a wide class of non-equilibrium dynamics.
Three-dimensional radiological anatomy of condyle trabecular bone based on a Volume-of-Interest analysis
Authors: Li Fan , Xu Xiangliang , Rong Qiguo , Wang Jianwei , Zhang Jiwu , Zhou Wen , Zhang Weiguang , Guo Chuanbin 
Published: June 2022

Objectives: Three-dimensional radiological anatomic characteristics of condyle trabeculae was obtained quantitatively based on a volume-of-interest (VOI) analysis. Methods: Nine human mandibular condyle specimens were scanned by micro-computed tomography (micro-CT). A total of 34 VOIs were selected from each condyle specimen, which were divided into six layers and four parts to analyze the morphological characteristics of trabeculae based on cylindrical VOIs with a diameter and height of 2 mm. One-way analysis of variance was used to compare the regional differences of morphological parameters among each layer and part. Results: Values for bone mineral density, bone volume/total volume, trabecular thickness, and trabecular bone number were greater in the anterior part compared with the posterior part; and the lateral part was larger than the medial part in the first, second, and third layers, while the medial part was larger in the fourth and fifth layers; these values in the first and sixth layers were much larger, while those in the third and fourth layers were smaller. Bone surface area/bone volume, trabecular spacing, and trabecular bone pattern factor were larger in the posterior part than in the anterior part; and the lateral part was larger than the medial part in the fourth and fifth layers, while the medial part was larger in the first and second layers. Conclusions: The morphological distribution of VOIs was anisotropic within trabecular bone of human mandibular condyles. The upper and lower ends of trabecular bone were much more compact, with higher bone density, trabecular thickness, and trabecular number than in the middle layers.
When Is Assortment Optimization Optimal?
Authors: Ma Will 
Published: June 2022

Assortment optimization concerns the problem of selling items with fixed prices to a buyer who will purchase at most one. Typically, retailers select a subset of items, corresponding to an “assortment” of brands to carry, and make each selected item available for purchase at its brand-recommended price. Despite the tremendous importance in practice, the best method for selling these fixed-price items is not well understood, as retailers have begun experimenting with making certain items available only through a lottery. In this paper, we analyze the maximum possible revenue that can be earned in this setting, given that the buyer’s preference is private, but drawn from a known distribution. In particular, we introduce a Bayesian mechanism-design problem where the buyer has a random ranking over fixed-price items and an outside option, and the seller optimizes a (randomized) allocation of up to one item. We show that allocations corresponding to assortments are suboptimal in general, but under many commonly studied Bayesian priors for buyer rankings, such as the Multinomial Logit and Markov Chain choice models, assortments are, in fact, optimal. Therefore, this large literature on assortment optimization has much greater significance than appreciated before—it is not only computing optimal assortments; it is computing the economic limit of the seller’s revenue for selling these fixed-price substitute items. We derive several further results—a more general sufficient condition for assortments being optimal that captures choice models beyond Markov Chain; a proof that Nested Logit choice models cannot be captured by Markov Chain, but can, to some extent, be captured by our condition; and suboptimality gaps for assortments when our condition does not hold. Finally, we show that our mechanism-design problem provides the tightest-known Linear Programming relaxation for assortment optimization under the ranking distribution model. This paper was accepted by Itai Ashlagi, revenue management and market analytics. Supplemental Material: The online appendix is available at https://doi.org/10.1287/mnsc.2022.4471 .
Application of 68Ga-citrate PET/CT for differentiating periprosthetic joint infection from aseptic loosening after joint replacement surgery
Authors: Xu Tingting , Zeng Yalan , Yang Xiao , Liu Guangfu , Lv Taiyong , Yang Hongbin , Jiang Fei , Chen Yue 
Published: June 2022

Aims We aimed to evaluate the utility of 68Ga-citrate positron emission tomography (PET)/CT in the differentiation of periprosthetic joint infection (PJI) and aseptic loosening (AL), and compare it with 99mTc-methylene bisphosphonates (99mTc-MDP) bone scan. Methods We studied 39 patients with suspected PJI or AL. These patients underwent 68Ga-citrate PET/CT, 99mTc-MDP three-phase bone scan and single-photon emission CT (SPECT)/CT. PET/CT was performed at ten minutes and 60 minutes after injection, respectively. Images were evaluated by three nuclear medicine doctors based on: 1) visual analysis of the three methods based on tracer uptake model, and PET images attenuation-corrected with CT and those not attenuation-corrected with CT were analyzed, respectively; and 2) semi-quantitative analysis of PET/CT: maximum standardized uptake value (SUVmax) of lesions, SUVmax of the lesion/SUVmean of the normal bone, and SUVmax of the lesion/SUVmean of the normal muscle. The final diagnosis was based on the clinical and intraoperative findings, and histopathological and microbiological examinations. Results Overall, 23 and 16 patients were diagnosed with PJI and AL, respectively. The sensitivity and specificity of three-phase bone scan and SPECT/CT were 100% and 62.5%, 82.6%, and 100%, respectively. Attenuation correction (AC) at 60 minutes and non-AC at 60 minutes of PET/CT had the same highest sensitivity and specificity (91.3% and 100%), and AC at 60 minutes combined with SPECT/CT could improve the diagnostic efficiency (sensitivity = 95.7%). Diagnostic efficacy of the SUVmax was low (area under the curve (AUC) of ten minutes and 60 minutes was 0.814 and 0.806, respectively), and SUVmax of the lesion/SUVmean of the normal bone at 60 minutes was the best semi-quantitative parameter (AUC = 0.969). Conclusion 68Ga-citrate showed the potential to differentiate PJI from AL, and visual analysis based on uptake pattern of tracer was reliable. The visual analysis method of AC at 60 minutes, combined with 99mTc-MDP SPECT/CT, could improve the sensitivity from 91.3% to 95.7%. In addition, a major limitation of our study was that it had a limited sample size, and more detailed studies with a larger sample size are warranted. Cite this article: Bone Joint Res 2022;11(6):398–408.
Social support and C-reactive protein in a Québec population cohort of children and adolescents
Authors: Fairbank Eloïse J. , McGrath Jennifer J. , Henderson Mélanie , O’Loughlin Jennifer , Paradis Gilles 
Published: June 2022

ObjectiveRobust evidence exists for the health-enhancing benefits of social support in adults. Inflammatory processes are thought to be an important mechanism linking social support and health risk. Less is known about the relation between social support and chronic inflammation during childhood and adolescence, or when the association emerges during the lifespan.MethodData from the population-representative 1999 Quebec Child and Adolescent Health and Social (QCAHS) survey were analyzed. Youth aged 9, 13, and 16 years (N= 3613) and their parents answered questions about social support. A subsample (n= 2186) completed a fasting blood draw that was assayed for C-reactive protein (CRP).FindingsHigher social support was significantly associated with lower hs-CRPlog, after controlling for age, sex, body mass index (BMI Z-score), medication use, puberty, ethnoracial status (French-Canadian), smoking, household income, and parental education (F= 25.88,p= < .001, TotalR2adj= 10.2%). The association was largely similar for boys and girls, and strengthened with age.ConclusionGreater social support was linked to lower chronic low-grade inflammation in a large sample of children and adolescents. Effect sizes were small and consistent with prior findings in the adult literature. Importantly, these findings provide evidence that the relation between social support and inflammation emerges early in the lifespan. Future work should consider broader, more encompassing conceptualizations of social support, the role of social media, and prospective trajectories of social support and inflammatory markers.
Analysing the impact of modifiable risk factors on cardiovascular disease mortality in Brazil
Authors: Gaspar Renato Simões , Rezende Leandro F. M. , Laurindo Francisco Rafael Martins 
Published: June 2022

Objectives
We have examined the impact of changes in modifiable risk factors on CVD mortality in 26 Brazilian states from 2005 to 2017.

Methods
Data were acquired from the Global Burden of Diseases study (GBD) and official sources of the Brazilian government, totalling 312 state-year observations. Population attributable fractions (PAFs) were calculated to determine the number of deaths attributed to changes in each risk factor. Fixed-effects multivariable linear regression models were performed, adjusting for income, income inequality, poverty and access to healthcare.

Results
Between 2005 and 2017, CVD deaths reduced by 21.42%, accompanied by a decrease in smoking (-33%) and increases in hyperglycaemia (+9.5%), obesity (+31%) and dyslipidaemia (+5.2%). Reduction in smoking prevented or postponed almost 20,000 CVD deaths in this period, while increased hyperglycaemia exposure resulted in more than 6,000 CVD deaths. The association between hyperglycaemia and CVD mortality was 5 to 10 times higher than those found for other risk factors, especially in women (11; 95%CI 7 to 14, deaths per 1-point increase in hyperglycaemia exposure). Importantly, the association between hyperglycaemia and CVD mortality was independent of socioeconomic status and access to healthcare, while associations for other risk factors after the same adjustments.

Conclusion
Reduction in smoking was the risk factor that led to the highest number of CVD deaths prevented or postponed, while hyperglycaemia showed the most deleterious association with CVD mortality. Health policies should aim to directly reduce the prevalence of hyperglycaemia to mitigate the population burden of CVD in Brazil in the future.