bluuebunny/crossref_metadata_2025_split huggingface dataset:
Brucelosis como causa de fiebre persistente en un trabajador de la salud de Cali, Colombia. Reporte de caso.
Authors: Araque-Villaquiran Fernando , Peña Guevara Antonio Alejandro , Carvajal-Mazuera Antonio Jose , Loaiza Giraldo Juliana 
Published: June 2022

Introducción. La brucelosis es la principal zoonosis a nivel mundial. Es transmitida al ser humano principalmente por el consumo de productos no pasteurizados, así como por exposición ocupacional. Las manifestaciones son inespecíficas lo que conlleva a un reto diagnóstico para el clínico, siendo una de las causas que pueden explicar la fiebre de origen desconocido y la cual no se tiene como etiología relevante dado su poca incidencia en nuestro medio, dejándose como una patología probable una vez se tengan descartadas las enfermedades más frecuentes y prevalentes.
Resumen del Caso. Resumen del caso: Presentamos a un hombre joven trabajador del área de la salud con antecedente de queratocono y urolitiasis quien ingresó al servicio de urgencias por cuadro febril agudo asociado a cefalea, mialgias y artralgias con sospecha inicial de infección por dengue. Sin embargo, dada la persistencia de la fiebre por más de 96 horas tras realizarse múltiples estudios negativos y múltiples consultas al servicio de urgencias requiriendo vigilancia de forma estricta, y bajo la sospecha epidemiológica de posible cuadro de zoonosis, se consideró realizar pruebas de detección para brucelosis mediante aglutinación por antígenos febriles siendo positivo para B. abortus en títulos altos de 1:160. Se corroboraron los hallazgos mediante prueba de aglutinación por rosa de Bengala y finalmente con inmunoensayo enzimático (ELISA) con resultado positivo para IgM e IgG. Se dio tratamiento con rifampicina y doxiciclina por 6 semanas con mejoría completa sin recurrencia.
Discusión. La brucelosis puede presentarse como un cuadro febril inespecífico que si bien es muy poco frecuente en nuestro medio debe tenerse como probabilidad etiológica dado el área rural y las pocas medidas de vigilancia epidemiológica y de salubridad en el adecuado proceso de pasteurización aún en proceso de Industrialización. En este reporte mostramos que la sospecha clínica y el uso de ayudas diagnósticas de detección indirectas permitieron hacer el diagnóstico sin que estas sean las de mejor rendimiento dada su baja especificidad y posibilidad de estar presentes en múltiples procesos infecciosos, pero en el caso de este paciente fue la clave para lograr el origen de la fiebre de origen desconocido. Si bien la mortalidad es baja, la terapia antibiótica combinada reduce la recurrencia y las complicaciones asociadas.
ANÁLISE DE INUNDAÇÕES EM BACIAS MONTANHOSAS NO SUL DO BRASIL POR MEIO DE MONITORAMENTO E MODELAGEM
Authors: Szymasnki Fernanda Dagostin , Melo Vasconcellos Sofia , Kobiyama Masato , Giehl Marcos Ricardo , Corseuil Cláudia Weber 
Published: June 2022

Bacias hidrográficas montanhosas são mais propensas aos perigos naturais, devido à ocorrência de eventos hidrológicos de alta intensidade e às características geomorfológicas destes locais, como o relevo declivoso e a presença de leques aluviais. O presente estudo teve como objetivo avaliar a inundação em bacias hidrográficas montanhosas no sul do Brasil, por meio de monitoramento e modelagem com HEC-HMS e HEC-RAS 2D, visando o mapeamento de perigo de inundação. Realizou-se um levantamento dos registros históricos de inundação, ocorridos em 2007 nas regiões de leque aluvial dos rios Molha Coco e Malacara. O HEC-HMS foi calibrado e validado com dados monitorados de vazão. Os hidrogramas com as vazões máximas simuladas pelo HEC-HMS foram propagados no modelo HEC-RAS 2D. Com essas vazões foram gerados mapas de profundidades, velocidades e índice de perigo de inundação para os períodos de retorno de 5, 100 e 200 anos. Os mapas de perigo mostraram que, o maior valor do índice de perigo de inundação foi encontrado dentro da calha dos rios e nos locais de avulsão. Nesses locais, existem pousadas, restaurantes e residências, que podem sofrer danos estruturais e expor as pessoas ao perigo de um evento de inundação de magnitude elevada.Palavras-chave: Rio Montanhoso. Mapeamento de perigo.HEC-RAS 2D.Monitoramento. Flood analysis in mountain basins in southern Brazil through monitoring and modelingA B S T R A C TMountain basins are more prone to natural hazards, due to occurrence of highly-intensive hydrological events, and local geomorphic characteristics, such as steep hillslopes and the alluvial fans. The present study aimed to assess the flood hazard degree in mountain basins in southern Brazil, through monitoring and modeling with HEC-HMS and HEC-RAS 2D. A survey of the historical flood records, which took place in 2007 in the alluvial fan regions of the Molha Coco and Malacara rivers, was carried out. The HEC-HMS was calibrated and validated with monitored flow data. The hydrographs with the maximum flow rates simulated by the HEC-HMS were propagated in the HEC-RAS 2D model. With these flows, maps of depth, velocity and flood hazard index were generated for the return periods of 5, 100 and 200 years. Potential hazard maps show that the highest value of the flood hazard index was found within river channels and at avulsion sites. In these places, there are inns, restaurants and residences, which can generate damage and expose people to the flood hazard with high magnitude.Keywords: Mountain river. Hazard mapping. HEC-RAS 2D. Monitoring.
Recording surface runoff in the field: a simple detector made of polypropylene
Authors: Salemi Luiz Felippe , Da Costa Silva Robson Willians , Fernandes Rafael Pires , Morgan Berteli de Andrade Tatiana , Barbosa de Camargo Plínio , Martinell Luiz Antonio , De Moraes Jorge Marcos 
Published: June 2022

Surface runoff is an extremely important hydrologic flowpath since it transports soil and pollutants. For this reason, low cost methods are needed to detect such process in the field. In the present paper, we present a simple surface runoff detector made of polypropylene. Its low cost along with its high repeatibility allow for the use of a high number of detectors in the field to elucidate spatial variability as well as to trace overland flow route. Simple demonstrations of the method are provided. With this simple detector, more knowledge can be obtained on this important hydrologic pathway which is related to soil erosion and transport of a number of potential harmful substances to water bodies.
Green synthesis of silver nanoparticles from papaya seed extracts with alkaloid content for antibacterial application
Authors: Surura Hedya Nadhrati , Abdullah Hairus , Ginting Sahna Ferdinand , Tandanu Erny , Ikhtiari Refi 
Published: June 2022

This research aims to develop a silver nanoparticle (AgNPs) using several plant extracts for antibacterial application. The papaya seed extract has been fractioned by n-hexane, ethyl acetate, water, and ethanol. The n-hexane fraction was the only fraction that succeeded in synthesizing AgNPs. The characterization methods showed AgNPs marked at 430 nm with UV-Vis and 1640 cm-1 with FTIR. SEM observed the aggregation of spherical AgNPs at the 200 nm scale. The particle size of 91.3 nm was measured with PSA that confirmed the nanoscale of the synthesized material. All fractions contained alkaloid compound, and ethyl acetate fraction showed a group of indole with specific wavenumber at 2623 cm-1, 1737 cm-1, and 1237 cm-1 representing N-H, C=O, C-N, respectively. All fractions at every concentration (25%, 50%, 75%, 100%) have been tested and showed the medium effect on bacterial growth inhibition. Among all fractions, the AgNPs n-hexane fraction has the highest bacterial effect, which was indicated by mean values of inhibition zone 7.2 mm against S.aureus, as well as 6.6 mm against E.coli. ANOVA analysis showed that AgNPs n-hexane fraction has a significant inhibition zone compared to other fractions against S.aureus (p=0.002), but not significant to E.coli (p=0.128). The insignificant results on E.coli because of gram-negative bacteria's biophysical characteristics, such as membrane cell wall and flagellin. This research emphasized that AgNPs could be synthesized via a green process of nucleation by using plant extract that effectively inhibits the growth of S.aureus and E.coli. Further studies on the mechanism of the antibacterial effect at the molecular level might be investigated soon.
Dharar as a Reason for Divorce Lawsuit in Fiqh and Legislation of Some Muslim Countries: Study on Indonesia, Bahrain, Sudan, Qatar, and Morocco
Authors: Trigiyatno Ali , Sutrisno Sutrisno 
Published: June 2022

This paper aims to explain dharar as a reason for divorce in the legislation of five Muslim countries, namely Indonesia, Bahrain, Sudan, Qatar, and Morocco. The five countries were chosen with consideration of representing the Sunni Islamic School and one Shia Islamic School. The approach used is a normative approach combined with a comparative method of the law. Primary legal materials are acts and other legislation relevant to the topic of discussion. The results show that the five countries equally provide room for divorce for the wife if she is experiencing dharar, the judge or hakam is obliged to reconcile the two disputing spouses, dharar includes physical and psychological, and the accusation must be proven using evidence generally applicable in procedural law. As for the difference, only Indonesia emphasizes cruelty and physical abuse, while other countries are general. Morocco is the most complete in regulating dharar as a reason for divorce and has several specifics such as violating the marriage agreement which is categorized as dharar. Morocco also regulates compensation due to ḍarar suffered by the wife, while the other four countries do not discuss it in their family law.TRANSLATE with x EnglishArabicHebrewPolishBulgarianHindiPortugueseCatalanHmong DawRomanianChinese SimplifiedHungarianRussianChinese TraditionalIndonesianSlovakCzechItalianSlovenianDanishJapaneseSpanishDutchKlingonSwedishEnglishKoreanThaiEstonianLatvianTurkishFinnishLithuanianUkrainianFrenchMalayUrduGermanMalteseVietnameseGreekNorwegianWelshHaitian CreolePersian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster PortalBack//
Potensi Antibakteri Ekstrak Etanol Daun Kecipir (Psophocarpus tetragonolobus (L.) DC) Terhadap Pertumbuhan Escherichia coli dan Staphylococcus aureus In Vitro
Authors: Henaulu Adudin H , Kaihena Martha 
Published: June 2022

Kecipir (Psophocarpus tetragonolobus (L.) DC) merupakan tanaman polong-polongan (fabaceae) yang sudah lama di kenal masyarakat Indonesia. Buahnya dimanfaatkan oleh masyarakat sebagai sayuran dan pengobatan seperti obat bisul, daunnya secara empiris digunakan sebagai obat tradisional. Penelitian ini bertujuan untuk mengetahui potensi dari daun kecipir (P.tetragonolobus(L.) DC)) sebagai antibakteri terhadap pertumbuhan Escherichia coli dan Staphylococcus aureus. Penelitian ini menggunakan daun kecipir segar yang dikeringanginkan dan diekstraksi dengan metode maserasi menggunakan pelarut etanol 96%. Uji aktivitas antibakteri terhadap E. coli dan S. aureus menggunakan metode difusi agar dengan pembandingceptazidine 30 Î¼g.Penelitian terdiri dari 6 perlakuan dan 3 kali ulangan yaituP0 (menggunakan aquades steril sebagai control negatif),P1 (konsentrasi EEDK 20%), P2 (konsentrasi EEDK 40%), P3 (konsenterasi EEDK 60%),K4 (konsenterasi EEDK 80%), P5 (konsentrasi EEDK100%) dan P6 (menggunakan ceptazidime 30 Î¼g) sebagai kontrol positif. Hasil penelitian menunjukkan ekstrak etanol daun kecipir berpotensi sebagai antibakteri terhadap E. colidan St. aureus, hal ini dibuktikan dengan adanya zona bening yang dihasilkan EEDK dengan konsentrasi 20;40;60,80 dan 100% untuk E.coli berturut turut dari P0 sampai P6 sebesar0,00; 3.83; 9.86; 12,17;15,63;17;17 dan 17.69. sedangkan besar zona hambat untuk St.aureus berturut turut dari P0 sampai P6 sebesar 0,00; 0,00; 3,67; 4,55; 5,33; 6.17 dan 13.83dimana EEDK lebih berpotensi menghambat E. coli dibandingkan St. aureus
Artificial Intelligence-based Technological-Oriented Knowledge Management, Innovation, and E-Service Delivery in Smart Cities: Moderating Role of E-Governance
Authors: Bokhari Syed Asad Abbas , SeungHwan Myeong 
Published: June 2022

<p> </p>
<p><strong>Abstract</strong></p>
<p>The fundamental goal of this research is to investigate the quantitative relationship between technology-oriented knowledge management, innovation, e-governance, and smart city performance using knowledge management-based service science theory and diffusion of innovation theory. Previous research has found a connection between knowledge management, innovation, e-governance, and e-service delivery. We believe that these are not only direct connections but also contextual and interactive relationships, so we explored the significance of innovation as a mediator between knowledge management and e-service delivery. Furthermore, we investigated the moderating impact of e-governance on the relationship between innovation and e-service delivery. Using SPSS to analyze data from 569 participants in South Korea, Pakistan, Japan, and Bangladesh, we discovered that these direct relationships are contextual in the sense that innovation mediates the relationship between knowledge management and e-service delivery and e-governance moderates the correlation between innovation and e-service delivery. Based on the outcomes from quantitative analysis, all our proposed hypotheses in this study were supported significantly.</p>
Slowly Progressive Limb-Girdle Weakness and HyperCKemia – Limb Girdle Muscular Dystrophy or Anti-3-Hydroxy-3-Methylglutaryl-CoA-Reductase-Myopathy?
Authors: Hiebeler Miriam , Franke Raimo , Ingenerf Maria , Krause Sabine , Mohassel Payam , Pak Katherine , Mammen Andrew , Schoser Benedikt , Bönnemann Carsten G. , Walter Maggie C. 
Published: June 2022

Background: Anti-3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR)-myopathy is a usually rapidly progressive form of immune-mediated necrotizing myopathy (IMNM). Rarer clinical courses show slow progression and resemble the phenotype of limb-girdle dystrophy (LGMD). Objective: We demonstrate the difficulties in differentiating LGMD versus anti-HMGCR-myopathy. Methods: We report on a 48-year-old patient with slowly progressive tetraparesis and hyperCKemia for more than 20 years. Results: Due to myopathic changes in initial and second muscle biopsy and typical clinical presentation, the patient was diagnosed with LGMD 20 years ago; despite comprehensive genetic testing including exome diagnostics, the genetic cause of disease could not be identified. Finally, HMG-CoA reductase antibodies were detected, confirming the diagnosis of anti-HMGCR-myopathy. By re-work-up of a second muscle biopsy specimen from year 2009, the diagnosis of a IMNM was made in retrospect. Seven cycles of high-dose immunoglobulins were administered; patient reported outcome measures have mildly improved. Conclusion: Patients with clinical LGMD phenotype, degenerative changes in muscle biopsy but without genetic confirmation of the disease should be tested for HMG-CoA-myopathy, thereby allowing for an early start of treatment.
Biological aspects of cultivation and application of active metabolites of B. subtilis probiotic
Authors: Popov V. S. , Svazlyan G. A. , Naumov N. M. 
Published: June 2022

Relevance. In modern research, the topic of metabiotics is considered as one of the current directions in the development of probiotics, in the future — as a new class of metabiotics. The article presents the results of studies during the cultivation of the probiotic microorganism B. subtilis in a grain nutrient medium from naked oats, and a scientific and practical substantiation of an experimental probiotic suspension during the formation of microbiocenosis and metabolism of the gastrointestinal tract in early weaning piglets.Methods. As the basis of nutrient media for obtaining metabolites of the probiotic culture of Bacillus subtilis, sprouted and non-sprouted oat grains of the naked variety Nemchinovsky were used at the rate of 100 g of crushed raw material per 3 l of water. The mass fraction of proteinogenic amino acids in experimental probiotic suspensions (EPS) was studied by capillary electrophoresis. The scientific and economic experiment was carried out according to the method of A.I. Ovsyanikov, 1976.Results. In nutrient media based on oats (O, OP), the number of CFU of probiotic microorganisms has a certain variability. The increase in the abundance of B. subtilis CFU continued up to 6 days, in the OP sample it reached 5.8·107 CFU/cm, after what it decreased until 8th day down to 15.5·106 CFU/cm3. At the same time, the synthesis of amino acids is higher compared to control (germinated grain): lysine — in the range of 7.85–10.53 g/l, methionine — 2.03–2.35 g/l, leucine + isoleucine — in the range 5.79– 9.7 g/l. Indicators of protein metabolism are within the physiological norm in piglets of experimental groups. In piglets that received an experimental probiotic suspension, a more pronounced antagonistic effect, during the formation of microbiocenosis, was manifested to conditionally pathogenic bacteriaif they were given B. subtilis, obtained on a medium based on sprouted oats.
Comparative morphological aspect of the study of bones of domestic and wild animals
Authors: Ziruk I. V. , Kopchekchi M. E. , Egunova A. V. , Tarasova A. A. 
Published: June 2022

At present, there is not enough information in the available literature about the anatomical features of the skull bones of various animal species, which is relevant when conducting forensic veterinary and medical examinations. Understanding of the structure of living organisms is impossible without anatomical preparations; it is necessary to clearly understand the place and position of each organ, to know all the options for anatomical relationships with neighboring organs. Knowledge of topographic anatomy is extremely important for the practitioner, it is necessary for successful diagnosis and subsequent treatment. The purpose of this work is to compare the bones of the skull of a cat, rabbit and hare, as well as to study their structure and morphometric parameters.Objects and methods. The objects of the study were the skulls of domestic and wild animals: a domestic outbred cat, a rabbit of the Gray giant breed, a brown hare. The work was carried out in several stages: digestion with the addition of sodium bicarbonate, cleaning, bleaching with a 3% hydrogen peroxide solution, drying, followed by morphometric measurement and visual comparison.Results. In a cat, the premaxillary bone and supraorbital process are absent, the hook of the pterygoid bone is long and rounded inwards. In rabbit and hare skulls, the anterior and posterior supraorbital processes are present on the frontal bone, and the hook of the pterygoid bone is short, sharp, and straight. The interparietal bone of the hare merged with the occipital, while in the rabbit and cat it exists as an independent bone. The information provided will greatly facilitate the conduct of a veterinary forensic examination in the investigation of crimes related to poaching.
Clinical and Genetic Characteristics of Coronaviruses with Particular Emphasis on SARS-CoV-2 Virus
Authors: Iwanicka Joanna , Iwanicki Tomasz , Kaczmarczyk Marcin , Mazur Włodzimierz 
Published: June 2022

Abstract
The rapidly spreading Coronavirus Disease 2019 (COVID-19) pandemic has led to a global health crisis and has left a deep mark on society, culture, and the global economy. Despite considerable efforts made to contain the disease, SARS-CoV-2 still poses a threat on a global scale. The current epidemiological situation caused an urgent need to understand the basic mechanisms of the virus transmission and COVID-19 severe course. This review summarizes current knowledge on clinical courses, diagnostics, treatment, and prevention of COVID-19. Moreover, we have included the latest research results on the genetic characterization of SARS-CoV-2 and genetic determinants of susceptibility and severity to infection.
Genomic Analysis of an Excellent Wine-Making Strain Oenococcus oeni SD-2a
Authors: Liu Longxiang , Peng Shuai , Song Weiyu , Zhao Hongyu , Li Hua , Wang Hua 
Published: June 2022

Abstract

Oenococcus oeni is an important microorganism in wine-making-related engineering, and it improves wine quality and stability through malolactic fermentation. Although the genomes of more than 200 O. oeni strains have been sequenced, only a few include completed genome maps. Here, the genome sequence of O. oeni SD-2a, isolated from Shandong, China, has been determined. It is a fully assembled genome sequence of this strain. The complete genome is 1,989,703 bp with a G+C content of 37.8% without a plasmid. The genome includes almost all the essential genes involved in central metabolic pathways and the stress genes reported in other O. oeni strains. Some natural competence-related genes, like comEA, comEC, comFA, comG operon, and comFC, suggest that O. oeni SD-2a may have natural transformation potential. A comparative genomics analysis revealed 730 gene clusters in O. oeni SD-2a homologous to those in four other lactic acid bacteria species (O. oeni PSU-1, O. oeni CRBO-11381, Lactiplantibacillus plantarum UNQLp11, and Pediococcus pentosaceus KCCM40703). A collinearity analysis showed poor collinearity between O. oeni SD-2a and

O. oeni PSU-1, indicating great differences in their evolutionary histories. The results provide general knowledge of O. oeni SD-2a and lay the foundation for specific gene function analyses.
PERANCANGAN SISTEM INFORMASI PENGGAJIAN BERBASIS WEB PADA CV. NADYA PRINTING
Authors: Syarif Arief Rama , Triyadi Tedi 
Published: June 2022

Teknologi informasi dimasa sekarang ini semakin berkembang dengan cepat. Teknologi informasi mempunyai peranan penting dalam kehidupan masyarakat , terutama dalam hal bisnis. Proses bisnis mampu berjalan baik dan tersistematis dengan teknologi informasi yang canggih. Penerapan teknologi informasi menjadikan salah satu solusi dalam menunjang kegiatan harian perusahaaan agar lebih efisien dan juga sebagai solusi menangani berbagai permasalahan dalam mencapai tujuan perusahaan yang lebih baik. Teknologi komputer mampu menjadi solusi dalam pemecah masalah dari tingkat yang ringan sampai yang rumit sekalipun. Sistem informasi dan teknologi tersebut menghasilkan suatu proses pengambilan keputusan , perencanaan, dan strategi bisnis perusahaan. CV Nadya Printing merupakan perusahaan jasa percetakan. Sistem penggajian yang digunakan pada CV Nadya Printing masih menggunakan cara konvensional. Penulis mencoba merancang aplikasi berbasis Web dengan menerapkan model waterfall. Aplikasi tersebut digunakan untuk mempermudah sistem penggajian dan mengakuratkan perhitungan gaji pokok, lembur dan pembuatan laporannya bulanan.