bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stimulus‐specific remodeling of the neuronal transcriptome through nuclear intron‐retaining transcripts
Authors: Mazille Maxime , Buczak Katarzyna , Scheiffele Peter , Mauger Oriane 
Published: September 2022

AbstractThe nuclear envelope has long been considered primarily a physical barrier separating nuclear and cytosolic contents. More recently, nuclear compartmentalization has been shown to have additional regulatory functions in controlling gene expression. A sizeable proportion of protein‐coding mRNAs is more prevalent in the nucleus than in the cytosol, suggesting regulated mRNA trafficking to the cytosol, but the mechanisms underlying controlled nuclear mRNA retention remain unclear. Here, we provide a comprehensive map of the subcellular localization of mRNAs in mature mouse cortical neurons, and reveal that transcripts retained in the nucleus comprise the majority of stable intron‐retaining mRNAs. Systematically probing the fate of nuclear transcripts upon neuronal stimulation, we found opposite effects on sub‐populations of transcripts: while some are targeted for degradation, others complete splicing to generate fully mature mRNAs that are exported to the cytosol and mediate rapid increases in protein levels. Finally, different forms of stimulation mobilize distinct groups of intron‐retaining transcripts, with this selectivity arising from the activation of specific signaling pathways. Overall, our findings uncover a cue‐specific control of intron retention as a major regulator of acute remodeling of the neuronal transcriptome.
Indonesian Efl Students’ Perception Towards Online Learning: Voices From Freshmen
Authors: Abdur Rohim Agil 
Published: September 2022

Covid-19 pandemic has inevitably shifted the conventional face-to-face learning in higher education institution to online learning. This study examined the perceptions of Indonesian EFL students, especially freshmen, towards online learning. Employing quantitative descriptive design with 83 respondents, this study focused on 3 aspects; 1) students’ perception, 2) students’ preferences, and 3) advantage and disadvantage of online learning based on students’ experience. The result showed that based on students’ perception 1) online learning is effective (53%, n = 44) to improve English proficiency, and somewhat effective (42.2%, n = 35) to improve social competences, 2) even though students’ enjoyment shows positive trends, they still prefer face-to-face learning (62.7%, n = 52) rather than online learning (37.3%, n = 31), and 3) the most frequent choose advantage of online learning is able to stay at home (79.5%, n = 66), while the most frequent disadvantage is less interaction with lecturers and classmates (74.7%, n = 62). This research has proven that the implementation of online learning earned numerous positive perceptions, followed with several challenges that need to be overcome by any means.
Twelve Weeks of Aerobic Training to Increase VO₂max in Sedentary Young Males
Authors: Moscatelli Fiorenzo , Polito Rita , Porro Chiara , Eronia Sara , Sessa Francesco , Monda Marcellino , Cibelli Giusseppe , Monda Vincenzo , Messina Giovanni , Valenzano Anna 
Published: September 2022

Study purpose. The aim of this study was to verify the effect of three sessions of aerobic training, for a period of 12 weeks, on VO2max and on the distance covered during the test.
Materials and Methods. Fifteen sedentary males were recruited in this study. VO2max was investigated using Cooper test. Aerobic intervention lasted for 12 weeks. The exercise the subjects were performing for the first 6 weeks was supervised aerobic training, 3 times per week at 60–75% of heart rate max (HRmax) (The first two weeks at 60–65 % HRmax, third and fourth week at 65–70% HRmax, fifth and sixth week at 70–75% HRmax). Afterwards, the subjects continued supervised aerobic training for 6 weeks until the twelfth week at 70–75% HRmax.
Results. After 8 weeks of aerobic training, a significant increase in distance covered during the Cooper test (p<0.001) and a significant increase in VO2max (p < 0.001) were observed.
Conclusions. In this study, it was found that 12 weeks of aerobic training have a positive impact on VO2max improvement and, therefore, completing 3 sessions of this type of training per week has a positive impact on aerobic parameters.
Association between Medial Longitudinal Arch with Static and Dynamic Balance among Recreational Badminton Players
Authors: Han Chang Zhong , Subramaniam Ambusam , Zainudin Fairus Fariza , Krishnan Vasanthi Rajkumar 
Published: September 2022

The study purpose was to examine the association between the Medial Longitudinal Arch (MLA) and balance among recreational badminton players.
Materials and methods. Total of 48 recreational badminton players aged 18–40 (24 males and 24 females) were recruited. Navicular Drop Test (NDT), Single Leg Stance Balance Test (SLSBT) and Modified Star Excursion Balance Test (mSEBT) were assessed on both dominant and non-dominant leg. Participant’s foot type was categorized using NDT scores according to difference of navicular height in weight bearing and relax sitting; static balance was grouped based on the time (seconds) the players were able to maintain balance during the SLSBT; and dynamic balance was grouped based on the percentage of distance reached in mSEBT.
Results. The study results revealed a significant association between the MLA of dominant (p<0.05) and non-dominant leg (p=0.02) with static balance among recreational badminton players. However, there is no significant association between the MLA of dominant (Anterior: p=0.39; Posteromedial: p=0.34; Posterolateral: p=0.98) and non-dominant leg (Anterior: p=0.39; Posteromedial: p=0.54; Posterolateral: p=0.07) with dynamic balance.
Conclusions. The current study concludes that there is a significant association between the MLA and static balance. However, no changes were seen in dynamic balance. Thus, coaches and trainers may look into the MLA of players to improve their static balance, which can further improve their sports performance. Future studies are recommended to examine the effects of dynamic balance in more depth with increased sample size.
Simulation of Competitive Activities of Skaters in Short-Track
Authors: Kholodova Olha , Shemchuk Vadym , Trachuk Sergii , Semenenko Viacheslav , Brychuk Mariia , Pidoprygora Maksym 
Published: September 2022

Modeling of competitive activity forms the basis for the rationalization and improvement of those means and methods that are used in sports training of athletes. In this regard, a hypothesis was put forward that predictive skating models will ensure the achievement of a certain level of sports results in short-track speed skating.
Study purpose. The aim of the study was to develop a prognostic model of the competitive activity of elite athletes at a distance of 500 m in short-track on the basis of regression analysis with a focus on achieving specified results.
Materials and methods. The study used an analysis of official competition protocols, modeling method, statistical analysis. The behavior of changes in the speed of skating at a distance of 500 m in 173 elite athletes was analyzed. The main components of competitive activity in short-track were revealed.
Results. The results obtained have theoretical significance which lies in the scientific substantiation of the need to improve competitive activity on the basis of its studying and the building of skating models. Their practical significance consists in the development and use of models of competitive activity of elite athletes at a distance of 500 m in short-track, taking into account the construction of a skating option. The presented data are an action plan that allows you to purposefully manage the training process and improve the training of athletes in short-track speed skating at a distance of 500 m in an annual cycle. When processing the results of the study, the level of statistical significance was taken as p ≤ 0.05.
Conclusions. The informative characteristics of competitive activity that affect the result at a distance of 500 m include acceleration speed and running speed on the first, second, third and fourth laps of the distance, multiple correlation coefficient r = 0.985 (p < 0.01). These are objective criteria which are a system-forming factor that determines the structure and content of the training process of elite athletes, and allow monitoring the level of special readiness, as well as predicting the ways of further improvement and making timely corrections in the training process.
Archiving COVID-19: A Historical Literature Review
Authors: Greenwood Amanda 
Published: September 2022

ABSTRACT
The goal of this historical literature review is to make a macro-to-micro analysis of the effort to archive the COVID-19 pandemic, starting with a global view, moving to a national view, focusing on New York State, and ending with the examination of personal narratives within communities. This literature review will discuss the procedures and theories behind how the pandemic was archived from March 2020 to August 2021, with the intention that it will serve as a resource to help individuals understand this difficult and uncertain time from multiple perspectives. This investigation also aims to illuminate the differences in archival approaches to documenting the pandemic and suggests areas for deeper analysis and further research. A macro-to-micro analysis of archival work during the pandemic can also help archivists reevaluate their current methods and consider other ways to collect, evaluate, curate, and preserve history for posterity in times of crisis.
A study of clinico-histopathological correlation in leprosy
Authors: Rajput Vishal , Vishwanath Suvernkar Suparna , Rajput Deepa , Wathore Nitin 
Published: September 2022

Leprosy is a chronic infectious disease caused by Mycobacterium leprae. It principally affects the cooler parts of the body, mainly skin and peripheral nerves; it also involves muscles, eyes, bones, testis and internal organs. Histopathological study of leprosy is very important in understanding the disease, its varied manifestations and complications. Clinical diagnosis of early leprosy lesions offer difficulties even to experienced dermatologists and leprologists. A definitive diagnosis may be possible by histopathological examination. Histological diagnosis when available is deemed the gold standard for diagnosis of leprosy.: To diagnose the case of leprosy using skin biopsy specimen. To study the clinical and histopathological correlation among leprosy patients attending a tertiary referral center. To classify the lesion according to Ridley and Jopling (RJ) classification.: The present study was conducted over a period of 18 months from Jan 2019 to July 2020. Total 51 new suspected cases were selected on clinical ground attending dermatological OPD. These patients were subjected to skin biopsy. Histopathological classification done on the basis of Riedly- Jopling criteria. Out of total 51 cases 40 cases showing leprosy changes on histopathological examination.Majority of the patients were males (53.06%), while females (46.94%) constituted a minority with male to female ratio of 1.1:1.Both clinically and histopathologically BT constituted the predominant group (62.7%) and (54.7%) respectively, followed by LL (15.6%). Clinical diagnosis of early leprosy lesions offer difficulties even to experienced dermatologists and leprologists. A definitive diagnosis may be possible by histopathological & bacteriological examination.
Zaufanie a administracja publiczna. Aspekty prawno-administracyjne
Authors: Przybysz Piotr 
Published: September 2022

Wzrost zaufania w relacjach społecznych ma istotne znaczenie w społeczeństwach o wysoko rozwiniętej gospodarce, ponieważ jest przesłanką dalszego rozwoju. Rolą administracji publicznej jest więc stymulowanie wzrostu zaufania w społeczeństwie. Strategie rozwoju formalizowane w aktach prawnych i realizowane przez administrację publiczną wskazują zatem zaufanie społeczne jako jeden z czynników wymagających wzmocnienia.
Zaufanie jest potrzebne również administracji publicznej do efektywnego wykonywania jej zadań zarówno w skali makro, jak i w relacjach z poszczególnymi jednostkami. Nakaz działania w sposób zwiększający zaufanie do władzy publicznej jest wprost wyartykułowany w przepisach postępowania administracyjnego. W sferze spraw wykraczających poza te załatwiane w ramach postępowania administracyjnego nakaz ten można wywieść z zasad prakseologii oraz zasad etyki.
Społeczna akceptacja rozstrzygnięć planistycznych w zakresie rozwoju
Authors: Kokocińska Katarzyna 
Published: September 2022

Potrzeby społeczne i gospodarcze, wyznaczane celami polityki rozwoju społeczno-gospodarczego, wyrażane są w uchwalanych okresowo aktach polityki władzy wykonawczej — strategiach rozwoju, planach i programach. Są one nie tylko wyrazem kierunków reform, ale też punktem odniesienia dla działalności organów administracji publicznej. Planowanie rozwoju dotyka interesów wielu podmiotów, ukierunkowując ich działania na realizację celów motywowanych interesem publicznym. Dlatego istotne jest ustalenie prawnej dopuszczalności i zabezpieczenia wpływu społeczeństwa na treść rozstrzygnięć planistycznych w zakresie rozwoju.
Opracowanie dotyczy problematyki prawnej organizacji planowania rozwoju społeczno-gospodarczego — jego legislacyjnej konstrukcji strukturalnej i proceduralnej w kontekście realizacji idei społeczeństwa obywatelskiego. Analiza przepisów prawa pozwoliła na zidentyfikowanie standardów i ocenę prawnych instrumentów uczestnictwa obywateli w procesie planowania rozwoju i uzyskiwania społecznej akcepcji treści aktów polityki.
Czy istnieje prawo energetyczne? Część 1: przedmiot, podmioty i metoda regulacji prawa energetycznego
Authors: Kosiński Eryk 
Published: September 2022

W 2022 roku mija 29 lat od głośnej dyskusji na temat statusu prawa gospodarczego (przede wszystkim publicznego prawa gospodarczego) jako nowej gałęzi prawa. Debata ta znalazła swoje miejsce w numerze 1 „Ruchu Prawniczego, Ekonomicznego i Socjologicznego” z 1993 roku. W niniejszej pracy autor podejmuje się próby odpowiedzi na pytanie, czy prawo energetyczne ist-nieje jako wyodrębniona dziedzina oraz gałąź prawa. Wydaje się przy tym, że dyskusja sprzed lat dotycząca publicznego prawa gospodarczego ma pełne zastosowanie do aktualnego zagadnienia samodzielności prawa energetycznego jako gałęzi prawa i dziedziny badawczej.
Analiza przedmiotu regulacji prawa energetycznego, szczególnych podmiotów — adresatów tej regulacji prawnej, metody regulacji oraz szczególnych jej celów (aksjologia regulacji) prowadzi do wniosku, że postawiona teza jest prawdziwa. W pracy zostały przedstawione ponadto geneza i rozwój prawa energetycznego, począwszy od XIX wieku. Autor dokonuje również przeglądu świa-towych podręczników z przedmiotowego obszaru, których liczba jest znacząca (zasadniczo są to pozycje anglojęzyczne). Wszystkie przytoczone analizy oraz argumenty przemawiają za wnioskiem o uznanie prawa energetycznego nie tylko za nową dziedzinę badawczą i dydaktyczną, ale także za nową gałąź prawa.
Opracowanie podzielono na dwie części. W części pierwszej prezentowane są argumenty świadczące o odrębności prawa energetycznego, odwołujące się do zagadnień fundamentalnych z tej perspektywy, to jest do przedmiotu regulacji prawa energetycznego, podmiotów regulacji oraz specyfiki metody tej regulacji. Natomiast w części drugiej przedstawione zostają dalsze argumenty popierające kluczową, przedmiotową tezę w zakresie odrębności prawa energetycznego.
Realizacja funkcji zarządu mieniem publicznym w prawie zamówień publicznych
Authors: Guziński Maciej 
Published: September 2022

Przy zamawianiu przez podmioty publiczne dóbr, robót, usług służących do wykonywania zadań publicznych przepisy ustawy Prawo zamówień publicznych wprowadzają określony reżim zachowania. Chodzi o możliwość, a niekiedy obowiązek podejmowania konkretnych działań faktycznych, a także czynności prawnych danej treści, determinujących postępowanie w zakresie wyboru wykonawcy oraz w pewnym zakresie również o sposób realizacji zadania. Ich niepodjęcie czy też spełnianie niezgodnie z przepisami ustawy wywołuje skutek w postaci konieczności ich powtórzenia, niekiedy nieważności całego postępowania, a w określonych sytuacjach także zawartej umowy. Wprowadzone ustawą regulacje ograniczają więc zachowania podmiotów zarządzających mieniem publicznym w sferze realizacji tego zarządu do wykonywania zadań publicznych. Wyraża się to w ograniczeniu ich swobody jako zamawiających w zakresie wydatkowania składników mienia na opłacenie zabezpieczenia realizacji zadań publicznych.
Możemy zatem uznać, że w ustawa wprowadza zasady, kryteria, tryby postępowania, którymi muszą się kierować organy i inne podmioty zarządzające mieniem publicznym, mając na względzie dobro publiczne (ochronę mienia publicznego). Reguły te odnoszą się równocześnie do działań oceniających i korygujących zachowanie podmiotów zarządzających mieniem publicznym w ramach zamówienia publicznego. Wskazuje to, że przepisy nowej ustawy Prawo zamówień publicznych, będące w określonych przypadkach swoistą procedurą postępowania przy wydatkowaniu publicznych środków finansowych, służą realizacji funkcji zarządu mieniem publicznym.
Penetrating Ocular Injury Management in Intraocular Foreign Body (IOFB) and Traumatic Cataract
Authors: Putri Nerissa Tamara , Firmansjah Muhammad , Prastyani Reni 
Published: September 2022

Highlight:

The management of penetrating ocular injury with IOFB and traumatic cataracts needs a thorough examination of the mechanism of injury, location, size, and composition of IOFB.
Endophthalmitis, retinal detachment, and development of PVR are potentially vision-threatment.

Abstract:
Most IOFB are metallic and found in males of productive age as a consequence of work-related accidents. A 45-year-old man complained of sudden blurred vision in the left eye (3/60 pinhole 5/12) after getting hit by a foreign body when cutting grass with a lawn mower. Anterior segment examination revealed a 10 mm long, one-plane, straight, full thickness, already sutured inferonasal corneal laceration, inferonasal traumatic iridectomy size 3x7 mm, and opaque lens. Head CT-scan revealed opacity with metallic density intraocularly. Ultrasonography revealed an echogenic lesion, particle-shaped with 100% RCS complex density, located at the inferonasal of the vitreous cavity. Focal laser photocoagulation was performed preoperatively because there was a tear at the superonasal of the retina. The patient underwent cataract extraction, intraocular lens implantation, vitrectomy, and IOFB extraction in a one-step procedure. IOFB was found at the inferonasal side of a vitreous cavity with size 3 x 1 mm, metallic, and not attached to the retina. Silicon oil tamponade was used as a precaution because there were retinal tears. Postoperatively, the left eye's visualacuity was 5/20. After 6 months, the silicon oil was evacuated and the visual acuity became 5/8.5.
Ferning and Schirmer Test 1 for the Detection of Grading Severity of Dry Eye Syndrome in Post Phacoemulsification Patients
Authors: Zubaidah Tengku Siti Harilza , Lubis Rodiah Rahmawaty , Feriyawati Lita 
Published: September 2022

Highlights:
1. Females were the most gender who suffer from dry eye syndrome than males.2. Undergone phacoemulsification patients had frequent dry eye syndrome.3. Post-phacoemulsification patients were not statistically significant between the Ferning and the Schirmer test.

Abstract:
Dry eye syndrome is a multifactorial disease on the surface of the eyeball characterized by loss of tear film homeostasis, which is associated with eye symptoms, where there is tear instability and hyperosmolarity, inflammation, and damage to the surface of the eye, as well as neurosensory disorders that act as the cause of this syndrome. The aim of this study was to identify relationship between the Ferning pattern and the Schirmer test 1 in post-phacoemulsification patients. The design of this study was an analytical observational study with a cross-sectional data collection method where the Ferning and Schirmer test 1 were examined to determine the severity of dry eye syndrome in post-phacoemulsification patients. The Ferning test was assessed according to Rolando’s classification. In this study, it was found that the gender who suffer from dry eye syndrome are women. The most considerable age is age ≥ 60 years (56,7%). The results showed that the majority of patients experienced dry eyes measured with the Ferning test, and these results were following the previous Schirmer Test 1 examination. The Ferning and Schirmer tests were found to be abnormal in most of the subjects. It was found that there was a significant relationship between the Ferning pattern and the Schirmer test with the calculation of the t-value of 7.345 with a p-value of 0.001. There was a statistically significant difference between the results of Ferning and the Schirmer test in post-phacoemulsification patients.
Late pruning of the vine
Authors: Deloire Alain , Pellegrino Anne 
Published: September 2022

In the current climatic context, with milder winters leading to earlier budburst in most wine regions, vines are exposed to the risk of spring frosts for a longer period. Depending on the year, frost can lead to yield losses of between 20 and 100 %, jeopardizing the economic survival of wine estates. In addition, by destroying young shoots, spring frosts can impact the following season’s production, by reducing the number of canes available for pruning, for example. Late pruning is one method to combat spring frosts (Ravas, 1912; Frioni et al., 2019).
Lateral retinacular release combined with MPFL reconstruction makes a meaningful role in the treatment of Recurrent Patellar Dislocation: by a digital tensiometer test
Authors: wenhao zhang , Mou Limin , Yuan Zhiyu , Han Mingzhan , Gao Jian , Aierdixing Abuilaiti , Ma Qiang , Xie Xiaochen 
Published: September 2022

Abstract
Purpose: Medial patellofemoral ligament (MPFL) reconstruction combined with lateral retinacular release (LRR) has become a common treatment for recurrent patellar dislocation, but it has not been feasible to find a reliable and definitive figure to compare the change in soft tissue tension on both sides of the patella before and after LRR. The aim of this study was to verify the change in graft tension by means of a digital tensiometer.
Methods: Fifty patients, aged 18-40 years, were included in this study, treated with MPFL reconstruction simplely and no other osteopathic surgery. After the graft had passed through the femoral tunnel, graft tension was measured by connecting a digital tensiometer, and the change in graft tension was analysed before and after LRR, together with pre- and post-operative knee function scores ( Lysholm score and kujala score) and radiographic angle (patellar congruence angle,PCA;PTA patellar tilt angle,PTA).
RESULTS: All 50 patients (52 knees) underwent MPFL reconstruction combined with LRR, with statistically significant differences in graft tension from 35.61±4.25N to 24.00±4.23N before and after LRR as measured by a digital tensiometer, and Kujala score and Lysholm score from 51.40±14.39 to 92.23± 4.74 and from 48.17±9.52 to 91.88±5.07, respectively, and PCA and PTA from 16.51±5.97° to 2.34±3.37° and from 25.43±4.53° to 11.62±2.54°, respectively, with statistically significant differences.There were no significant post-operative complications, with the exception of three patients who experienced slight discomfort at the patellar end when the weather became colder.At a mean follow-up of 53 months, there were 7 (14%) complications and no postoperative redislocations were observed.94% of the patients were satisfied with the results of the operation.
CONCLUSION: LRR is meaningful for patients with recurrent patellar dislocation and is effective in reducing tension on reconstruction grafts.