bluuebunny/crossref_metadata_2025_split huggingface dataset:
What Makes A Perinatal Woman Suicidal? A Grounded Theory Study
Authors: Reid Holly E. , Pratt Daniel , Edge Dawn , Wittkowski Anja 
Published: March 2022

Abstract
Background: Suicide is a leading cause of maternal death during pregnancy and up to a year after birth. Psychological and psychosocial risk factors for maternal suicide ideation and behaviour have been identified but do not account for why mothers begin to experience suicidal thoughts. Qualitative research offers a way of identifying what might drive mothers to initially consider suicide and then go on to act on such thoughts; crucial for the development of assessments to identify, and interventions to target, maternal suicide ideation and behaviour. We aimed to develop a grounded theory outlining what makes women think about suicide and/or engage in suicidal behaviour during pregnancy and the first 12 months following birth?Method: Semi-structured interviews were conducted with 12 mothers in the UK who had suicidal thoughts during pregnancy and/or the first year following birth. A constructivist approach to grounded theory was adopted which guided the data collection and analysis processes. Results: We developed a model outlining the theorised process of psychological factors that culminates in mothers experiencing suicidal thoughts and then making a suicide attempt during the perinatal period. The process was initiated when mothers felt attacked by motherhood which led to feeling like a failure, self-identifying as a “bad mother” and subsequent appraisals of entrapment and/or defeat. When nothing resolved the distress and as mothers collated reasons for why they perceived they needed to die, suicidal behaviour became a viable and appealing option. We theorised that mothers might make a suicide attempt when they entered a state of intense “darkness” brought on by a trigger, followed by a temporary lapse in the conflict between the desire to live and desire to die and an opportunity to attempt.Conclusions: Participants stressed the rapid onset of suicidal thoughts. We suggest that healthcare professionals enquire about the mother’s feelings towards the baby and of isolation, how she views herself as a mother, feelings of entrapment and defeat during routine contacts to aid identification and prevention of suicidal ideation/behaviour. Suggested interventions to prevent suicidal thoughts and behaviour include helping women manage their expectations for pregnancy and the postpartum period.
Multi‑Strategy Equilibrium Optimizer: An Improved Meta-Heuristic Tested On Numerical Optimization And Engineering Problems
Authors: Li Yu , Liang Xiao , Liu Jingsen , Zhou Huan 
Published: March 2022

Abstract
In order to solve complex numerical optimization problems and engineering problems more effectively, an Improved Equilibrium Optimizer (IEO) based on multi-strategy optimization is proposed. Firstly, Tent mapping is used to initialize the algorithm instead of randomly generating initial population in basic Equilibrium Optimizer. The diversified initial population lays a good foundation for global search of the algorithm. Moreover, nonlinear time parameter is used to update the position equation, which dynamically balances the exploration and exploitation phases of IEO. Finally, Lens Opposition‑based Learning (LOBL) is introduced, which can avoid local optimization by improving the population diversity of the algorithm. Simulation experiments are carried out on 23 classical functions, IEEE CEC2017 problems and IEEE CEC2019 problems, and the stability of the algorithm is further analyzed by Friedman statistical test and box plots. Experimental results show that IEO has good solution accuracy and robustness. In addition, six engineering design problems are solved, and the results show that IEO not only has high optimization efficiency, but also can achieve cost minimization.
The association between early onset of alcohol, smokeless tobacco and marijuana use with adult binge drinking in United States
Authors: Dai Zheng , Wang Kesheng 
Published: March 2022

Abstract
1) BackgroundBinge drinking remains significant public health problems in United States. To date, less is known how the early onset of substance use and other factors impacted the severity of adult binge drinking. 2) MethodThe 2018 National Survey on Drug Use and Health data was used to identify binge drinking (binary and in number of days in the past month). Age at onset was categorized four groups as 1–12, 13–14, 15–17, or beyond 18. Weighted multivariate logistic regression and Poisson regression analyses were performed to examine the association between early onset of alcohol, smokeless tobacco, and marijuana use with binge drinking. 3) ResultsThe severity of binge drinking was statistically significantly associated with substance use (2.66 days in a month), early (before age 15) onset of alcohol, smokeless tobacco, and marijuana use (3.20–4.93 days, all p-values < 0.0001), after accounting for the covariates. Past year substance use disorder is strongly associated with binge drinking. 4) ConclusionsThe severity of adult binge drinking is significantly associated with early onset of substance use including alcohol, smokeless tobacco, and marijuana. Continued efforts are warranted to improve substance use prevention and treatment tailored for adolescents and youth to prevent development of adult binge drinking.
Zinc Status is Related To Dialysis Adequacy In Peritoneal Dialysis Patients: A Cross-Sectional Study In Central China
Authors: Zhang Danfeng , Li Dandan , Zhao Xinyu , Chen Mengpin , Zhu Yuyu , Wang Deguang , Liu Guiling 
Published: March 2022

Abstract
Background: Zinc displays an essential role in regulation of inflammation and redox oxidative stress and patients on peritoneal dialysis (PD) are prone to develop zinc deficiency due to decreased dietary intake and losses via PD effluent and urinate. This study was aimed to evaluate the prevalence rate of zinc level in Chinese patients on PD and the relationship between zinc level and total Kt/V (tKt/V) on PD; Methods: A cross-sectional study of a cohort of 116 patients with end-stage kidney disease (ESKD) receiving PD was conducted. Peritoneal dialysis Kt/V were identified and patients were grouped as high tKt/V (＞1.7) ( n=78) group and low tKt/V（＜1.7）(n=38) group. The zinc level in whole blood were measured using atomic absorption spectroscopy（AAS）; Results: The zinc level in whole blood showed significantly higher values in patients with high tKt/V than those with low tKt/V (5.47±0.47 and 5.02±0.35, p=0.031, respectively). Age, zinc, albumin and cholesterol level were identified as independent predictors of Kt/V in PD patients by multivariate analysis. The prognostic value of zinc of high tKt/V was revealed as an area under the curve (AUC) of 0.799 (95% CI :0.717-0.881, p＜0.001) with a sensitivity of 80.8% and specificity of 73.7%. Compared with albumin and cholesterol, Delong’test was empolyed and the results showed that zinc in whole can predict the better adequacy of PD significantly (p＜0.05); Conclusions: Zinc level in whole blood are low in patient undergoing peritoneal dialysis. Low zinc concentration is associated with low tKt/V in PD patients, suggesting that zinc level in whole blood may serve as an independent factor of dialysis quality of PD patients.
The Effect of Acceptance and Commitment Therapy on Youth with Body Dysmorphic Disorders Symptoms: A Randomized Clinical Trial
Authors: Torkian Akram , Zanjani Zahra , Pourkmali Zahra , Omidi Abdollah 
Published: March 2022

Abstract
Background
Body dysmorphic disorder (BDD) is the most distressing body image disorders. The aim of this study was to evaluate the efficacy of acceptance and commitment therapy (ACT) in improving psychological problems in individuals with BDD symptoms.
Methods
This was a randomized clinical trial study with 34 eligible patients with BDD symptoms were recruited from Kashan city in 2021. These individuals were randomly assigned to either an intervention group (n = 17) with 8 weekly ACT sessions or a placebo group (n = 17). Used assessments included Yale-Brown Obsessive-Compulsive Scale Modified for Body Dysmorphic Disorder (Y-BOCS-BDD), Depression Anxiety Stress Scales 21-item version (DASS-21), Cognitive Fusion Questionnaire (CFQ), and Body-Image Acceptance and Action Questionnaire (BI-AAQ). Data were analyzed by using SPSS 26.
Results
The results revealed that there was no significant difference in demographic variables of either age or gender. On the other hand, statistical analyze showed that two groups had the significant difference in term of body symptoms severity (F = 4.89), cognitive fusion (F = 9.18), emotional symptoms (depression F = 4.03, anxiety F = 4.02, and stress F = 4.87) in the post-test.
Conclusion
It can be said ACT has a positive effect on body image flexibility, cognitive fusion, and emotional symptoms of young people with body dysmorphic disorders and it can improve their symptoms.
Intraoperative frozen section can reduce unnecessary second operation in breast cancer patients that failed to be diagnosed by previous core needle biopsy: a retrospective analysis of Chinese clinical practice
Authors: Xue Jialei , Li Jianwei , Gong Yue , Cui Qiuxia , Dai Li , Guo Tianwei , Liu Zhebin , Liu Guangyu 
Published: March 2022

Abstract
Objective: The value of frozen section in the intraoperative diagnosis of breast cancer that failed to be diagnosed by previous core needle biopsy (CNB) is indeterminate. To evaluate and improve the clinical utility of frozen section on this kind of breast cancer, we conducted a retrospective data analysis and constructed a prediction model.Method: We reviewed data of breast cancer patients that failed to be diagnosed by previous CNB (CNB-undiagnosable) in Fudan University Shanghai Cancer Center (FUSCC) from May 1, 2006 to December 31, 2019. Clinical characteristics of patients were collected. the correlation between clinical features and false negative rate (FNR) of frozen sections was explored with logistic regression analysis, after which a nomogram was constructed to predict the probability of false negative.Result: The diagnostic sensitivity of frozen section on CNB-undiagnosable breast cancer was 67.18%, and the FNR was 32.82%. In multivariate analysis, papillary lesion (OR, 4.251; 95% CI, 2.804-6.492; P<0.0001) and sclerosing adenosis (OR, 3.727; 95% CI, 1.897-7.376; P= 0.0001) on CNB were risk factors of false negative, while clustered microcalcifications on mammography (OR, 0.345; 95% CI, 0.216-0.543; P < 0.0001) and ultrasonic BI-RADS category 4C-5 (OR, 0.250; 95% CI, 0.081-0.777; P = 0.0157) were favorable factors of true positive. The false negative rate of frozen section could be controlled at about 11% or less by the prediction of nomogram. Conclusion: Frozen sections are valuable in the intraoperative diagnoses of CNB-undiagnosable breast cancers. It is recommended to implement the intraoperative frozen sections for high-risk breast lesions with a low probability of false negative indicated by prediction, so as to minimize the occurrence of unnecessary second operation.
Forest Ecosystems and Evolution of Cattle Husbandry Practices of the Earliest Central European Farming Societies
Authors: Gillis Rosalind , Kendall Iain , Roffet-Salque Mélanie , Zanon Marco , Anders Alexandra , Arbogast Rose-Marie , Bogucki Peter , Brychova Veronika , Casanova Emmanuelle , Claßen Erich , Csengeri Piroska , Czerniak Lech , Domboróczki László , Fiorillo Denis , Gronenborn Detlef , Hachem Lamys , Jakucs János , Ilet Micheal , Lyublyanovics Kyra , Lenneis Eva , Marciniak Arkadiusz  , Marton Tibor , Oross Krisztián , Pavúk Juraj , Pechtl Joachim , Pyzel Joanna , Stadler Peter , Stäuble Harald , Vostrovská Ivana , Wijk Ivo van , Vigne  , Balasse Marie , Evershed Richard 
Published: March 2022

Abstract

Stable isotope signatures of domesticates found on archaeology sites provide information about past human behaviour, such as the evolution and adaptation of husbandry strategies. A dynamic phase in cattle husbandry evolution is during the 6th millennium BCE, where the first cattle herders of central Europe spread rapidly through diverse forested ecological niches, where little is known about pasturing strategies. Here we investigate cattle pasturing and foddering practices using a multi-regional dataset of stable isotope values (δ13C and δ18O; compound-specific stable isotopic analysis δ15N-amino acids and δ13C-dairy fats) measured from cattle bone and teeth, and pottery residues from early farming contexts, and palaeoenvironmental information. Our analysis reveals that farmers practiced different pasturing strategies with the intensive use of forested ecosystems in some areas for both graze and seasonal forage. We propose that the diversity of strategies is related to the adaptation of herding to new environments, which had a positive impact on cattle breeding and milk availability for human consumption.
The occurrence of the strongylid nematodes, Kalicephalus viparae viparae (Nematoda: Diaphanocephalidae), in viper Snake, Macrovipera lebetina (Reptilia: Viperidae), Southwestern Iran
Authors: Larki Sara , Alborzi Alireza , Bahramnejad Kia , Asadi Zeinab 
Published: March 2022

Abstract
An ancylostomatid Kalicephalus spp. is the common parasitic intestinal nematode of reptiles. West-Asian blunt-nosed viper, a venomous snake found in extensive areas of Iran. Between June - September 2017, two dead viper snakes were referred to the parasitology laboratory and examined for intestinal parasites. Several white elongated roundworms were collected and fixed to identify under light and scanning electron microscopes (SEM) based on morphological and molecular characteristics. For the molecular survey, some parts of identified worms were extracted and the ITS of nuclear ribosomal DNA (rDNA) amplified by PCR reaction. All collected hookworms were taxonomically identified as Kalicephalus viperae viperae and exposited in an individual branch far from of Ancylostomatidae species and close to A. braziliense with 88% discrepancies in the phylogenetic tree. The morphological characteristics and a large part of K. viperea viperea rDNA nucleotide sequence was reported in viper snakes for the first time in the world and Iran.
Inequality in energy transitions: Air pollution disparities amidst national decarbonization strategies
Authors: Goforth Teagan , Nock Destenie 
Published: March 2022

Abstract
Energy transitions and decarbonization require rapid changes to a nation's electricity generation mix. There are many feasible decarbonization pathways for the electricity sector, yet there is vast uncertainty about how these pathways will advance or derail the nation's energy equality goals. We present a framework for investigating how decarbonization pathways, driven by a least-cost paradigm, will impact air pollution inequality across different vulnerability groups in the US (e.g., low-income, high poverty or minority communities). We find that using least-cost optimization capacity expansion models without strict carbon or renewable energy technology mandates will fall short of achieving national energy equality. We find that Black or poor communities have higher co-pollutant concentrations during the energy transition, until a national mandate requires full deployment of renewable or low-carbon technologies. Thus, decisions regarding national decarbonization pathways must have strict mandates for equality outcomes or be driven by an equality-focused paradigm throughout the energy transition.
Clinical Analysis of the Etiological Spectrum of Bilateral Adrenal Lesions: a Large Retrospective, Single-center Study
Authors: Yan Fangfang , Zeng Jinyang , Chen Yulong , Cheng Yu , Pei Yu , Zang Li , Chen Kang , Gu Weijun , Du Jin , Guo Qinghua , Wang Xianling , Ba Jianming , Lyu Zhaohui , Dou Jingtao , Yang Guoqing , Mu Yiming 
Published: March 2022

Abstract
Purpose: To investigate the clinical characteristics, endocrinological function, and etiologies of patients with bilateral adrenal lesions.Methods: A retrospective study of 777 patients with bilateral adrenal lesions was conducted at the Chinese General Hospital of the People’s Liberation Army between January 2013 and January 2018. Patient demographic features, hormonal profiles, imaging findings, and histopathological findings were reviewed from the database records. Results: Of the 777 patients with bilateral adrenal lesions, 495 were men, and the mean age at diagnosis was 52.0±13.0 years. A total of 511 (65.8%) cases were benign, followed by adrenal metastases (n=224, 28.8%), pheochromocytoma (n=26, 3.3%), adrenal lymphoma (n=9, 1.2%), and adrenal corticocarcinoma (ACC) (n=7, 0.9%). Hormonal evaluation revealed that 34.3% of bilateral adrenal lesions were functional. The primary etiologies of functional lesions were primary aldosteronism (16.6%, 129/777) , and PBMAH (8.8%, 68/777). Patients with lymphoma and metastases were significantly older than those with benign nonfunctional lesions (60.4±11.0 years vs. 54.5±10.4 years and 57.9±10.8 years vs. 54.5±10.4 years, respectively; P<0.001). Lesions in adrenal lymphoma, ACC, pheochromocytoma, metastases, CAH, tuberculosis, and Cushing’s syndrome were significantly larger than benign nonfunctional lesions (all P<0.001). Conclusion: Benign adrenal lesions and metastases to the lungs are the most common causes of bilateral adrenal lesions, and primary aldosteronism and BMAH are the most prevalent functional lesions. In addition, our findings suggest that patients with lymphoma or metastases are older and possess larger masses.
Design and analysis of a plasmonic refractive index sensor with symmetrical cavities and rings.
Authors: HamidAbbasi  
Published: March 2022

Abstract
This paper analyzes and designs the structure of a sensor, the performance of which is evaluated by changing the refractive index. The structure of this sensor consists of two waveguides, eighteen cavities and nine rings. For better and more accurate results, we only change the refractive index of the middle ring and the refractive index of the other amplifiers remains constant. The results show that with increasing and changing the refractive index, the resonance wavelength will shift. This means that this method can be used to understand the refractive index and resonance wavelength. By changing the wavelength and refractive index and calculating the resonance amplitude curve (FWHM), three characteristics of sensitivity coefficient, figure of merit (FOM) and quality factor Q can be examined. These three characteristics, especially the sensitivity coefficient, tell us whether this sensor has a good performance or notIn this structure, the sensor sensitivity has reached 6591 nm / RIU. This means that the performance of the proposed sensor is better and more powerful than similar sensors and can achieve a more flexible amplitude of the wavelength. Also, the maximum figure of merit (FOM) is 43.73 nm / RIU and the highest quality factor Q is equal to 60.01. In the end, we come to the conclusion that this method has tremendous potential for use in various fields of measurement, such as biochemical, medical and military analysis. Also, all the diagrams obtained in this research have been drawn using MATLAB program.
Characterization of Resistome in Lactobacillus Genomic Sequences From the Human Gut
Authors: Moradi Jale , Fathollahi Matin , Halimi Shahnaz , Alvandi Amirhooshang , Abiri Ramin , Vaziri Siavash , Rezaei Akram 
Published: March 2022

Abstract

The gut is a complex environment inhabited by a wide range of bacterial species. Lactobacillus species constitute a significant proportion of this environment, and, due to their mobile genetic elements such as plasmids and transposons, are more likely to acquire and transfer antibiotic resistance genes through horizontal gene transfer (HGT). The current study obtained and analyzed 321 genome assemblies to determine the prevalence of intrinsic and acquired antibiotic resistance genes (ARGs) among Lactobacillus species colonizing the human gastrointestinal tract. A total of four high-frequency resistance genes were identified, including dfra42 (42%), poxtA (17.4%), lmrB (12%), and BJP-1 (7.7%), aside from dfra42, which is an intrinsic resistance gene, the other genes are acquired resistance genes. PoxtA was found in several different species, mainly in L. paracasei, whereas BJP-1 and lmrB were only found in one species, L. rhamnosus. IS5-like elements family transposase flanked 11% and 8% of detected lmrB and BJP-1, respectively, while, a variety of insertion sequences surrounded 22% of identified poxtA. Furthermore, to the best of our knowledge, this is the first report of BJP-1 in lactobacilli that would suggest it has transferred from soil microbiota to humans. According to the “One Health” perspective, early detection of a new reservoir would control the global spread of the antibiotic-resistant bacterial species between the three environments, which include humans, the environment, and animals. Finally, the study's findings may then highlight the possibility of lactobacilli acquiring or transmitting resistance to other species within or outside the human intestine.
Application Of 3D Printing Customized Bone Cement Molds In Reconstructing The Defect Of The Proximal Humerus And Distal Radius After Oncologic Resection: A Case Series Report
Authors: Ke Song , Ran Tianfei , Wang Chao , Zheng Lingling , He Yongqin , Wang Min 
Published: March 2022

Abstract
Background: Reconstructing the defect of the proximal humerus and distal radius after en bloc resection of tumors is challenging for surgeons. We present a defect reconstruction technique using bone cement prosthesis shaped by 3D printing customized molds in a case series as well as the oncologic and functional outcomes of these cases. Methods: A total of thirteen bone tumor cases (eight cases in the proximal humerus and five cases in the distal radius) of patients who experienced this reconstructive method from 2014-2019 were retrospectively reviewed. Local recurrence, metastases, complications, musculoskeletal tumor society score (MSTS score), and visual analogue scale (VAS) were used to evaluate the outcomes.Results: The average follow-up period was 46.5 months (range, 27-76 months). At the end of the follow-up, neither metastasis nor recurrence was found in all cases, and no patients demonstrated complications of fracture, infection, or implant loosening (only one patient who underwent proximal humerus resection and reconstruction complained of weakness in lifting the arms). The average MSTS score was 23.2 (77.2%, range, 66.7%-80%), and the average postoperative VAS was 1.31 ± 0.48 (range, 1-2).Conclusion: Bone cement prosthesis molded by 3D printing can be an effective and inexpensive option for reconstructing the proximal humerus and distal radius after en bloc resection of bone tumors. We recommend this method especially for elderly patients who need to undergo this procedure and do not require much function of the upper extremity.Level of evidence Ⅳ, a retrospective study.
18F-AIFNOTA-FAPI-04 Accumulation in Left Ventricular Myocardium in a Patient with Hypertensive Heart Disease
Authors: Xu Yi , Tang Yonjin , Wang Lu , Guo Jun , Ling Xueying , Wu Shaorong , Li Zicheng 
Published: March 2022

Abstract
A 62-year-old man with a history of hypertension for 20 years was admitted to our hospital. Echocardiogram showed thickened septum and decreased left ventricular diastolic function, indicating hypertensive heart disease. He underwent 18F-AIFNOTA-FAPI-04 PET/CT for suspected gastric cancer. Instead of aberrant tracer uptake in his stomach, uptake was observed unexpectedly in inferolateral wall of his left ventricle. This case suggests the possible role of 18F-AIFNOTA-FAPI-04 PET/CT in evaluation of hypertensive cardiac fibrosis/remodeling.