bluuebunny/crossref_metadata_2025_split huggingface dataset:
Contributions to the stereochemistry of zirconium oxysalts—part IV: syntheses and crystal structures of Zr2(OH)2(XO4)3·4H2O (X = S, Se), Zr(SO4)2·4H2O, and Zr(SeO3)2
Authors: Wildner Manfred , Lengauer Christian L. , Effenberger Herta , Giester Gerald 
Published: January 2022

AbstractZr2(OH)2(XO4)3·4H2O (X = S, Se), Zr(SO4)2·4H2O, and Zr(SeO3)2 were synthesized at low-hydrothermal conditions from mixtures of Zr2O2(CO3)(OH)2, the respective acids, and minor amounts of water. While Zr2(OH)2(XO4)3·4H2O (X = S, Se) and Zr(SO4)2·4H2O form crystals up to several tenths of a mm, Zr(SeO3)2 was mainly obtained as microcrystalline powder, single crystals rarely exceeded 10 μm in size. Samples were investigated by single-crystal X-ray techniques and in the case of Zr(SeO3)2 also by X-ray powder diffraction. The compounds Zr2(OH)2(XO4)3·4H2O (X = S, Se) crystallize in the Ce2(OH)2(SO4)3·4H2O structure type (C2/c, Z = 4, a = 13.034(2) / 13.308(3), b = 6.500(1) / 6.683(2), c = 15.056(3) / 15.383(4) Å, β = 96.27(1) / 96.81(1)°, V = 1267.9(4) / 1358.5(6) Å3 for X = S / Se, respectively). Tetragonal aniprisms Zr[8]O8 are edge-connected to dimers that share corners with XO4 tetrahedra forming a three-dimensional network. Zr(SO4)2·4H2O (Fddd, Z = 8, a = 5.498(1), b = 11.618(3), c = 25.893(6) Å, V = 1653.9(6) Å3) is isotypic with the respective selenate compound. Occasionally, pseudomerohedral twinning is observed, simulating a larger monoclinic C-centered unit cell. Again, tetragonal antiprisms Zr[8]O8 are formed; however, they are corner-linked with SO4 tetrahedra to Zr(SO4)2 layers interconnected solely by hydrogen bonds. Zr(SeO3)2 crystallizes in P21/c, Z = 2; a = 4.9724(3), b = 8.5992(5), c = 6.9447(3) Å, β = 110.128(3)°, V = 278.81(3) Å3 (unit cell from powder data) and belongs to the β-Sn(SeO3)2 structure type established further for Ti(SeO3)2 and Pb(SeO3)2. Isolated ZrO6 octahedra share corners with the selenite groups forming a three-dimensional network.
Graphical abstract
Altered pituitary morphology as a sign of benign hereditary chorea caused by TITF1/NKX2.1 mutations
Authors: Thust Steffi , Veneziano Liana , Parkinson Michael H. , Bhatia Kailash P. , Mantuano Elide , Gonzalez-Robles Cristina , Davagnanam Indran , Giunti Paola 
Published: January 2022

AbstractBenign hereditary chorea (BHC) is a rare genetically heterogeneous movement disorder, in which conventional neuroimaging has been reported as normal in most cases. Cystic pituitary abnormalities and features of empty sella have been described in only 7 patients with BHC to date. We present 4 patients from 2 families with a BHC phenotype, 3 of whom underwent targeted pituitary MR imaging and genetic testing. All four patients in the two families displayed a classic BHC phenotype. The targeted pituitary MR imaging demonstrated abnormal pituitary sella morphology. Genetic testing was performed in three patients, and showed mutations causing BHC in three of the patients, as well as identifying a novel nonsense mutation of the TITF1/NKX2-1 gene in one of the patients. The presence of the abnormal pituitary sella in two affected members of the same family supports the hypothesis that this sign is a distinct feature of the BHC phenotype spectrum due to mutations in the TITF1 gene. Interestingly, these abnormalities seem to develop in adult life and are progressive. They occur in at least 26% of patients affected with Brain-lung-thyroid syndrome. As a part of the management of these patients we recommend to perform follow-up MRI brain with dedicated pituitary imaging also in adult life as the abnormality can occur years after the onset of chorea.
Reduced autonomy workspace (RAW)—an interaction design approach for human-automation cooperation
Authors: Nylin Magnus , Johansson Westberg Jimmy , Lundberg Jonas 
Published: January 2022

AbstractLack of support for handling a reduction of autonomy in a highly autonomous automation may lead to a stressful situation for a human when forced to take over. We present a design approach, the Reduced Autonomy Workspace, to address this. The starting point is that the human and the automation work together in parallel control processes, but at different levels of autonomy cognitive control, such as setting goals or implementing plans, which is different from levels of automation. When autonomy is reduced, the automation should consult the human by providing information that has been aligned to the level at which the human is working, and the timing of the provision should be adapted to suit the human’s work situation. This is made possible by allowing the automation to monitor the human in a separate process. The combination of these processes, information level alignment and timing of the presentation, are the key characteristics of the Reduced Autonomy Workspace. The Reduced Autonomy Workspace consists of four phases: Identification of the need; evaluation of whether, and, if so, when, and how to present information; perception and response by the human; implementation of a solution by the automation. The timing of the information presentation should be adapted in real-time to provide flexibility, while the level of the information provided should be tuned offline and kept constant to provide predictability. Use of the Reduced Autonomy Workspace can reduce the risk for surprising, stressful hand-over situations, and the need to monitor the automation to avoid them.
“Manufacturing Life” in Real Work Processes? New Manufacturing Environments with Micro- and Nanorobotics
Authors: Moniz António Brandão , Krings Bettina-Johanna 
Published: January 2022

AbstractThe convergence of nano-, bio-, information, and cognitive sciences and technologies (NBIC) is advancing continuously in many societal spheres. This also applies to the manufacturing sector, where technological transformations in robotics push the boundaries of human–machine interaction (HMI). Here, current technological advances in micro- and nanomanufacturing are accompanied by new socio-economic concepts for different sectors of the process industry. Although these developments are still ongoing, the blurring of the boundaries of HMI in processes at the micro- and nano- level can already be observed. According to the authors, these new socio-technical HMIs may lead to the development of new work environments, which can also have an impact on work organization. While there is still little empirical evidence, the following contribution focuses on the question whether the “manufacturing (or working) life” using enhancement practices pushes the boundaries of HMI and how these effects enable new modes of working in manufacturing. Issues of standardization, acceleration of processes, and order-oriented production become essential for technological innovation in this field. However, these trends tend to lead to a “manufacturing life” in work environments rather than to new modes of work in industry.
In Situ and Ex Situ TEM Analysis of the Copper Precipitation in Martensitic Steel
Authors: Bambach Margarita D. , Szczepański Łukasz , Żak Andrzej M. 
Published: January 2022

Abstract
The conventional and in situ transmission electron microscopy imaging of quenched 1.5 pct Cu steel has shown that Cu phases are present even before aging and do not disappear after typical aging times. The 9R precipitates appear after 15 minutes of heating, but they are more noticeable after longer processing times. This suggests that the precipitation mechanisms in carbon steels deserve further analysis, especially because of the inevitable increase in the Cu content in the steel ingots.
Reuse of Electric Arc Furnace Slag as Filler for Nitrile Butadiene Rubber
Authors: Gobetti Anna , Cornacchia Giovanna , Ramorino Giorgio 
Published: January 2022

AbstractThis work shows an innovative application for electric arc furnace (EAF) slag: its use as a filler for nitrile butadiene rubber (NBR). Composites with various EAF slag contents were tested. It was found that the polymer matrix significantly reduces the leaching of slag (determined according to the standard CEN-EN 12457-2) incorporated in the NBR. The processability characteristics determined by the rheometric curves highlight that the EAF slag accelerates the crosslinking kinetics, reducing the production cycle time. Mechanical characterization demonstrated that EAF slag increases hardness and compression modulus. The ability to recover an imposed deformation quantified by the compression set is reduced as the EAF slag amount increases but remains below an acceptable value. It can be stated that in sealing systems, the EAF slag as a filler for NBR positively affects the compound properties. Moreover, NBR filled with EAF slag also has magnetic properties compared with standard rubber.
Uric Acid, Hypertensive Phenotypes, and Organ Damage: Data from the Pamela Study
Authors: Grassi Guido , Vanoli Jennifer , Facchetti Rita , Mancia Giuseppe 
Published: January 2022

Abstract
Purpose of Review
To examine published and unpublished data collected in the context of the Pressioni Arteriose Monitorate E Loro Associazioni (PAMELA) study on the relationships between serum uric acid (SUA), office and out-of-office blood pressure (BP), and organ damage.

Recent Findings
SUA values were directly and significantly related to a large number of covariates that participate at cardiovascular risk determination, such as blood glucose, total serum cholesterol, serum triglycerides, body mass index, and serum creatinine. Additional variables included echocardiographically-determined left ventricular mass index and BP values, the latter not just when measured in the office but also when evaluated at home or over the 24-h period. White-coat hypertension and masked hypertension were characterized, as sustained hypertension, by a significant increase in SUA levels, which were also directly related to different indices of 24-h BP variability. No substantial difference in SUA levels was found when data were analyzed according to the dipping or non-dipping nocturnal BP profile.

Summary
Data collected in the frame of the PAMELA study document the presence of a close relationship between SUA levels and BP values independently on the hypertensive phenotype patterns of BP increase (office, 24 h, or both) and nighttime BP profile. They also document the increase in SUA as a potential factor favoring the occurrence of new hypertension and new left ventricular hypertrophy.
End-of-Life Care in Patients with Cancer 16–24 Years of Age
Authors: Emerson Natacha D. , Tabuenca Krista , Bursch Brenda 
Published: January 2022

Abstract

Purpose of Review
To present new findings in order to aid in the provision of high-quality symptom management and psychosocial care for adolescents and young adults with advanced cancer at the end of life.

Recent Findings
Behavioral health providers support patients by teaching them symptom control skills, building legacies, and making meaning of their lives. Integration of cultural values is essential for comprehensive assessment and decision-making. Effective management of physiological symptoms and psychological distress begins with accurate communication about prognosis and goals of care that focus on patient preferences and priorities. Oncology teams promote quality of life and the successful management of fatigue, pain, decreased mobility, poor appetite, and dyspnea with the early inclusion of palliative care.

Summary
While provision of end-of-life care in a young person with cancer presents challenges, multidisciplinary teams can effectively accompany patients in this journey by prioritizing patient and family preferences to promote quality of life.
Palmitic Acid and Oleic Acid Differently Modulate TLR2-Mediated Inflammatory Responses in Microglia and Macrophages
Authors: Howe Anne-Marie , Burke Sinéad , O’Reilly Marcella E. , McGillicuddy Fiona C. , Costello Derek A. 
Published: January 2022

AbstractThe relationship between systemic immunity and neuroinflammation is widely recognised. Infiltration of peripheral immune cells to the CNS during certain chronic inflammatory states contributes significantly to neuropathology. Obesity and its co-morbidities are primary risk factors for neuroinflammatory and neurodegenerative conditions, including Alzheimer’s disease (AD). Dietary fats are among the most proinflammatory components of the obesogenic diet and play a prominent role in the low-grade systemic inflammation associated with the obese state. Saturated fatty acid (SFA) is largely implicated in the negative consequences of obesity, while the health benefits of monounsaturated fatty acid (MUFA) are widely acknowledged. The current study sought to explore whether SFA and MUFA differently modulate inflammatory responses in the brain, compared with peripheral immune cells. Moreover, we assessed the neuroinflammatory impact of high-fat-induced obesity and hypothesised that a MUFA-rich diet might mitigate inflammation despite obesogenic conditions. Toll-like receptor (TLR)2 mediates the inflammation associated with both obesity and AD. Using the TLR2 agonist lipoteichoic acid (LTA), we report that pre-exposure to either palmitic acid (PA) or oleic acid (OA) attenuated cytokine secretion from microglia, but heightened sensitivity to nitric oxide (NO) production. The reduction in cytokine secretion was mirrored in LTA-stimulated macrophages following exposure to PA only, while effects on NO were restricted to OA, highlighting important cell-specific differences. An obesogenic diet over 12 weeks did not induce prominent inflammatory changes in either cortex or hippocampus, irrespective of fat composition. However, we reveal a clear disparity in the effects of MUFA under obesogenic and non-obesogenic conditions.
Reconstructing curves from their Hodge classes
Authors: Cifani Maria Gioia , Pirola Gian Pietro , Schlesinger Enrico 
Published: January 2022

AbstractLet S be a smooth algebraic surface in $${\mathbb {P}}^3({\mathbb {C}})$$

P

3

(
C
)

. Movasati and Sertöz (Rend. Circ. Mat. Palermo 2:1–17, 2020) associate an ideal $$I_{\alpha (C)}$$

I

α
(
C
)

to the primitive cohomology class $$\alpha (C)$$

α
(
C
)

of C in S. We show that the equations of C can be determined by $$I_{\alpha (C)}$$

I

α
(
C
)

under numerical conditions. We apply this result to reconstruct rational curves and arithmetically Cohen-Macaulay curves from their cohomology classes. On the other hand, we show that the class $$\alpha (C)$$

α
(
C
)

of a rational quartic curve C on a smooth quartic surface S is not even perfect, that is, that $$I_{\alpha (C)}$$

I

α
(
C
)

is bigger than the sum of the Jacobian ideal of S and of the homogeneous ideals of curves D in S for which $$I_{\alpha (D)}=I_{\alpha (C)}$$

I

α
(
D
)

=

I

α
(
C
)

.
Effect of high nitrate contamination of groundwater on human health and water quality index in semi-arid region, South India
Authors: Ramalingam Saravanan , Panneerselvam Balamurugan , Kaliappan Shunmuga Priya 
Published: January 2022

Abstract
The specific objective of the present is to evaluate the human health issue due to the continuous consumption of nitrate-contaminated groundwater among the various age groups of people. In the study, 40 groundwater samples were collected during the post-monsoon season, and the major ions were analysed in a laboratory. Chadha plot revealed that weathering of parent rocks, ion exchange process and leaching of salts from the rocks are primary sources of groundwater contamination. Nitrate concentration varied from 24 to 78 mg/L with a mean of 46.45 mg/L. Nitrogen pollution index (NPI) value divulged that 40% and 17.5% of sample locations are moderately and significantly polluted due to elevated nitrate concentration in groundwater. The human health risk assessment model revealed that health issues are among the various age groups which are infants > kids > children > aged peoples > adults. The nitrate’s identified sources are leaching of salts from the rocks, using synthetic fertilizers, uncovered septic tanks and improper disposal of household waste from the residential area. Therefore, periodic inspection of water supply, health check-up and inspection of underground pipelines are the remedial measures that should be taken to reduce the severe effects of nitrate-contaminated drinking water in the study area.
A joint climate and nature cure: A transformative change perspective
Authors: Rusch Graciela M. , Bartlett Jesamine , Kyrkjeeide Magni Olsen , Lein Ulrika , Nordén Jenni , Sandvik Hanno , Stokland Håkon 
Published: January 2022

AbstractClimate change has considerably dominated science-policy dialogue, public debate, and subsequently environmental policies since the three “Rio Conventions” were born. This has led to practically independent courses of action of climate change mitigation and biodiversity conservation actions, neglecting potential conflicts among outcomes and with missed opportunities for synergistic measures. Transformative governance principles have been proposed to overcome these limitations. Using a transformative governance lens, we use the case of the Norwegian "Climate Cure 2030" for the Land Use, Land-Use Change and Forestry (LULUCF) sector to, first, illustrate the mechanisms that have led to the choice of climate mitigation measures; second, to analyze the potential consequences of these measures on biodiversity and greenhouse gas (GHG) emissions; and, third, to evaluate alternative measures with potential positive outcomes for biodiversity and GHG emissions/removals. We point to some mechanisms that could support the implementation of these positive actions.
Spectral Characteristics of GEO Satellite Arcing – 300 To 350 MHz
Authors: Ferguson Dale C. , Perillat Phil , Vayner Boris 
Published: January 2022

AbstractIn a series of previous papers, the detection of arcing on GPS, Van Allen Probe, and GEO satellites with the Arecibo Observatory Wm. E. Gordon 305 m radiotelescope has been reported and elaborated. In this paper, characteristics of the radiofrequency spectra of two true GEO satellites are reported as they were measured with the Arecibo Mock spectrometer every 9.6 microseconds, and are contrasted with spectra of impulsive RFI (RadioFrequency Interference) events. It is shown that the arc spectra in the 300–350 MHz range are not continuous, but consist of a number of narrow spectral lines. These lines are consistent within the duration of single arcs, but change between arcs, so that when averaged over many arcs, the appearance of a continuous spectrum is approximated. This behavior is replicated in the laboratory within charging-induced vacuum arcing on small solar array samples. In contrast, the spectrum of impulsive RFI (including, but not limited to lightning strokes) is essentially random from one 9.6 microsecond sampling interval to the next. Since the spectrum of a true arc changes little throughout many samples, it cannot be due to the risetime of the arc current, which is much less than one sampling interval. Furthermore, in laboratory experiments done at very high time resolution (< 1 ns), there is little correlation between the arc current spectra and the arcing RFI spectra, indicating that even arc current fluctuations within each arc can have little to do with the UHF spectra observed.
Application and benchmark of SPH for modeling the impact in thermal spraying
Authors: Jeske Stefan Rhys , Bender Jan , Bobzin Kirsten , Heinemann Hendrik , Jasutyn Kevin , Simon Marek , Mokrov Oleg , Sharma Rahul , Reisgen Uwe 
Published: January 2022

AbstractThe properties of a thermally sprayed coating, such as its durability or thermal conductivity depend on its microstructure, which is in turn directly related to the particle impact process. To simulate this process, we present a 3D smoothed particle hydrodynamics (SPH) model, which represents the molten droplet as an incompressible fluid, while a semi-implicit Enthalpy-Porosity method is applied for modeling the phase change during solidification. In addition, we present an implicit correction for SPH simulations, based on well-known approaches, from which we can observe improved performance and simulation stability. We apply our SPH method to the impact and solidification of Al$$_2$$

2

O$$_3$$

3

droplets onto a substrate and perform a comprehensive quantitative comparison of our method with the commercial software Ansys Fluent using the volume of fluid (VOF) approach, while taking identical physical effects into consideration. The results are evaluated in depth, and we discuss the applicability of either method for the simulation of thermal spray deposition. We also evaluate the droplet spread factor given varying initial droplet diameters and compare these results with an analytic expression from the previous literature. We show that SPH is an excellent method for solving this free surface problem accurately and efficiently.
Capacity Analysis of a Passenger Rail Hub Using Integrated Railway and Pedestrian Simulation
Authors: Pu Y. S. , Srikukenthiran S. , Morrow E. , Shalaby A. , Klumpenhouwer W. 
Published: January 2022

AbstractAs the level of passenger demand in rail transit systems increases, major railway stations in urban centres face serious capacity issues. Both analytical and simulation methods have been used to analyse complex station areas; however, prior efforts have only focused on either train or pedestrian movements with over-simplified assumptions that do not properly capture the impact of their interaction on capacity. This study applies an integrated crowd and transit simulation platform “Nexus” to simultaneously study the impact of pedestrian and train movements on the system performance of a complex railway station. Unlike other methods such as sequential simulation methods, the integrated simulation platform permits linkage between commercial-grade simulators. Instead of treating each simulator separately, this integrated method enables detailed modelling of how the train and crowd dynamic interact at station platforms. Such integration aims to explore the interactive effect on both types of movement and enable performance analysis possible only through this combination. To validate the model, a case study is performed on Toronto’s Union Station. Extensive data were collected, processed and input into railway and pedestrian models constructed using OpenTrack and MassMotion, respectively, and integrated via Nexus. Examining scenarios of increased levels of train and passenger volumes, a 9% drop in on-time performance of train operation is observed, while the level of service experienced by passengers on the platform deteriorates significantly due to crowding. Both length and variation in dwell time due to pedestrian movement are recognized as the main factors of performance deterioration, especially when the system approaches capacity limit. The simulation model produces estimates of the practical track-side capacity of the station and associated platform crowding levels, and helps identify locations where passengers experience severe overcrowding, which are not easily obtainable from mathematical models.