bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relacja z nauczycielem gry na instrumencie a poczucie własnej skuteczności muzyków i ich kariera zawodowa: badanie jakościowe
Authors: Molińska Weronika , Rajchert Joanna 
Published: February 2025

Wprowadzenie: Rozwój zawodowy to proces długotrwały, rozpoczynający się w dzieciństwie i trwający do wieku dojrzałego. Badania pokazują, że postrzegana przez uczniów jakość relacji nauczyciel-uczeń i poczucie ich własnej skuteczności wiążą się z samopoczuciem i postępami w nauce uczniów. Celem badania było określenie jakie czynniki, z perspektywy aktualnie pracujących zawodowo muzyków, były odpowiedzialne za kształtowanie się ich poczucia skuteczności muzyka oraz jakie było znaczenie poczucia skuteczności muzyków dla ich rozwoju ich ścieżki kariery artystycznej. Metoda: Przeprowadzono badanie jakościowe w formie indywidualnego wywiadu pogłębionego, częściowo ustrukturyzowanego. Dane z wywiadów zostały przeanalizowane przy użyciu refleksyjnej analizy tematycznej. Wyniki: Przy kształtowaniu się poczucia własnej skuteczności muzyka oraz przy podejmowaniu przez muzyków wyborów zawodowych największe znaczenie ma jakość relacji z nauczycielem prowadzącym oraz specyfika edukacji muzycznej. Wnioski: Wyniki zestawiono z dotychczasowymi badaniami z zakresu psychologii edukacji i pedagogiki, podkreślając znaczenie budowania wspierającej ucznia atmosfery nauczania oraz wzmacniania korzystnej relacji nauczyciela z uczniem, w celu zwiększenia poczucie własnej skuteczności uczniów, co dalej może prowadzić do rozwoju kariery zawodowej artystów.
Resistir a la insensibilidad. Reseña del libro Seeing Race Again. Countering Colorblindness Across Disciplines (2019), editado por Kimberlé Williams Crenshaw, Luke Charles Haris, Daniel Martinez HoSang y George Lipsitz (University of California Press)
Authors: Pastor Berdún Nicolás 
Published: February 2025

Reseña del libro Seeing Race Again. Countering Colorblindness Across Disciplines (2019), editado por Kimberlé Williams Crenshaw, Luke Charles Haris, Daniel Martinez HoSang y George Lipsitz (University of California Press).

Review of Seeing Race Again. Countering Colorblindness Across Disciplines (2019), edited by Kimberlé Williams Crenshaw, Luke Charles Haris, Daniel Martinez HoSang y George Lipsitz (University of California Press).
Del atardecer en el Támesis a la espesura de la selva. Salvajismo y civilización en El corazón de las tinieblas de Joseph Conrad.
Authors: Martí Mengual Lucía 
Published: February 2025

El objetivo de este ensayo es analizar la figura del primitivo salvaje en la novela de Conrad El corazón de las tinieblas, escrita en el contexto del colonialismo de finales del XIX. Para ello nos centraremos principalmente en la segunda parte de la novela, en la cual el protagonista retrata a la alteridad nativa más allá de la devastación causada por la explotación colonial. La idea general es considerar hasta qué punto Conrad asume o subvierte los tópicos antropológicos de la época y en qué medida podemos rastrear en el texto una imagen diferente del primitivo salvaje y, como reverso, una mirada crítica a las sociedades supuestamente civilizadas. Es por ello que nos detendremos a considerar las relaciones entre el texto de Conrad y algunos de los autores clásicos de la antropología del momento, así como a reflexionar sobre la perspectiva que se nos ofrece sobre el canibalismo de los nativos africanos, y, por último, consideraremos brevemente la idea del civilizado que se vuelve nativo (otro lugar común en las descripciones etnográficas de la época) que aparece en la novela.
Improving Website Usability with Design Thinking: A Case Study of BEM FMIPA Udayana University’s Website
Authors: Putra Ananda , Santiyasa I Wayan , Widiartha I Made , Darmawan I Dewa Made Bayu Atmaja 
Published: February 2025

Aims: This study aims to implement the Design Thinking methodology in the development of the BEM Faculty of MIPA, Udayana University’s company profile website. The primary objective is to enhance user experience by addressing usability issues and improving accessibility, navigation, and overall functionality.
Study Design: This research adopts a user-centered design approach, utilizing the Design Thinking framework, which consists of five phases: Empathize, Define, Ideate, Prototype, and Test.
Place and Duration of Study: This study was conducted at the Faculty of Mathematics and Natural Sciences, Udayana University, over a period of five months.
Methodology: The research study adopts a case study design and employs mixed methods, combining both qualitative and quantitative approaches. The research began with a quantitative preliminary usability evaluation using the System Usability Scale (SUS), where the existing website received a score of 51.75 (ranked F), indicating significant usability issues. In the next phase, qualitative data was gathered through surveys, interviews, and literature studies to identify user pain points, particularly related to website navigation, design, and content accessibility. The insights from these qualitative methods informed the redesign of the website. Using the principles of Design Thinking, the website was restructured with an emphasis on an intuitive interface, improved information hierarchy, and enhanced interactivity. Finally, the redesigned website prototype was subjected to usability testing to evaluate improvements and gather both qualitative and quantitative feedback.
Results: The implementation of Design Thinking resulted in significant improvements in user satisfaction and website efficiency. The SUS score rose from 51.75 to 88.96, indicating a major increase in usability. Efficiency tests showed a 28.36% improvement, with users requiring fewer clicks to complete tasks. These results highlight the new website's enhanced intuitiveness, aesthetics, and alignment with user expectations.
Conclusion: The application of Design Thinking in website development successfully improved the usability and functionality of the BEM Faculty of MIPA company profile website. By adopting a user-centered approach, the redesigned website effectively addresses user needs, enhances accessibility, and provides a better overall experience. Future research may explore further refinements and the integration of advanced features to maintain long-term user engagement.
Phytochemical Profiling of Athimathura Chooranam a Polyherbal Formulation: A GC-MS Analysis
Authors: Rakshana  , Shalini  , Chitra  
Published: February 2025

Introduction: Athimathura Choornam, a traditional Siddha formulation, has been employed for centuries to treat various ailments.
Aim: This study is aimed to investigate the phytochemical profile of Athimathura Choornam by using Gas Chromatography-Mass Spectrometry (GC-MS) analysis.
Methods: Gas chromatography-mass spectrometry (GC-MS) analysis was conducted on a Nexis GC 2030 MS AP 2020 NX instrument, by utilizing reagents including ethanol, concentrated sulfuric acid, concentrated nitric acid, and water. Sample preparation involved diluting 1g of sample in 50ml ethanol, followed by filtration using helium gas as the carrier."
Results: The GC-MS chromatogram revealed 10 bioactive compounds, including squalene compounds. The identified compunds are Alpha. Terpinyl acetate,(Terpenoid)1,3 Cyclohexadine, Benzene propanoic acid (belongs to Aromatic carboxylic acids),Butan 2 one(Ketones),2,4- decadienamide (amide group),2-[4-methyl-6(2,6,6-trimethyl cyclohex-1enyl)hexa-1,3,5-trienyl](belongs to Terpenoids,Sesquiterpenes),1-(4-hydroxy-3methoxyphenyl)dec-4-en-3one(Phenylalkanones), Retrofractamide-A (Belongs to alkaloids, amides and Peptides),5-hydroxy-1-(-4-hydroxy-3-methoxy phenyl)decan-3one (Phenylalkanones), squalene (Terpenes group). The compounds were identified by quantifying using peak area and internal standard methods. The results revealed the presence of therapeutically relevant compounds, by substantiating the traditional uses of Athimathura Choornam.
Conclusion: This study provides a capacious phytochemical profile of Athimathura Choornam, paving the way for further pharmacological and clinical investigations.
Contribution of NF‐κB and p53 in the glutamate‐induced apoptosis
Authors: Uberti Daniela , Grilli Mariagrazia , Memo Maurizio 
Published: July 2002

AbstractExposure of primary cultures of cerebellar granule cells for 15 min to micromolar concentrations of glutamate results in cell death of both necrotic and apoptotic types. Among the intracellular events triggered by glutamate, we identified two transcriptional factors: the p50 member of the NF‐κB family and the tumor suppressor phosphoprotein p53. Pretreatment of the cultures with aspirin, which inhibits NF‐κB activation, or with specific p53 antisense oligonucleotide, which inhibits p53 transcription, resulted in a complete prevention of glutamate‐induced p53 induction and apoptosis. These findings suggest the existence of a transcriptional program activated by glutamate receptor stimulation in which p50 and p53 play a relevant role. Then, we studied the expression of two p53 downstream genes that could participate in the glutamate‐induced pro‐apoptotic pathway: p21, which codes for an inhibitor of different cyclin dependent kinases, and MSH2, which codes for a protein involved in the recognition and repair of DNA mismatches. We found that primary cerebellar neurons expressed p21 and MSH2 at very low levels in basal conditions. However, very soon after a brief exposure of the cells to glutamate, the expression of both proteins was dramatically enhanced.On these bases, we propose NF‐κB, p53, p21 and MSH2 as relevant contributors of the glutamate‐induced pro‐apoptotic pathway. Understanding this cascade of nuclear events may unravel specific targets for pharmacological intervention for those neurological diseases in which excitatory amino acid‐induced apoptosis plays a relevant role.
Plasma brain natriuretic peptide — an independent predictor of cardiovascular mortality in acute heart failure
Authors: Yu Cheuk M. , Sanderson John E. 
Published: July 2002

AbstractPurpose:To examine the prognostic importance of both plasma atrial natriuretic and B‐(brain natriuretic peptide) following an episode of acute heart failure.Subjects and methods:A prospective cohort of 91 patients admitted into hospital with acute heart failure were recruited. After initial in‐hospital management plasma ANP and BNP levels were measured by radioimmunoassay, and echocardiography was performed on the same day. Patients were followed up for 12 months and the main outcome measure was cardiovascular death.Results:Plasma ANP and BNP levels were significantly higher in patients who died of a cardiovascular cause within 12 months (P < 0.001 and P < 0.0001, respectively) or at 1‐month (P < 0.05 and P < 0.001) after recruitment. By Kaplan‐Meier estimated life‐table curves, patients with above median plasma ANP or BNP levels had significantly higher 1‐year mortality (42.5% vs. 11.6%, both P < 0.005). By multivariate Cox proportional hazard regression analysis, the plasma BNP level was the most important prognostic factor predicting mortality (χ2 = 18.3, P < 0.0001), followed by age (χ2 = 11.5, P < 0.001). Other factors including ANP, left ventricular ejection fraction by M‐mode echocardiography, pulmonary arterial pressure, sex, cause of heart failure as well as New York Heart Association class were not significant.Conclusion:A plasma BNP level has independent and at least short‐term prognostic significance in patients admitted with acute heart failure. This non‐invasive and readily available blood test should be considered for risk stratification in patients with acute heart failure.
The basics of heart failure management: are they being ignored?
Authors: Horan Mairead , Barrett Fionnula , Mulqueen Mary , Maurer Brian , Quigley Peter , McDonald Kenneth M. 
Published: July 2002

AbstractBackgroundAdvances have been made in the medical management of congestive heart failure. However, there is concern that these changes may not be transmitted to the heart failure population in the community. Other impediments to improved prognosis, such as failure to apply non‐pharmacological strategies and poor patient comprehension may also be prevalent in the community.AimsThe purpose of this study was to assess physician practice and patient knowledge in a heart failure population admitted to a University Hospital in Ireland. Methods: Patients admitted with a primary diagnosis of heart failure were studied. Estimation of ejection fraction was used to subdivide the population into heart failure with impaired and normal systolic function. Patients' course in hospital was noted with reference to management by cardiology or internal medicine, use of angiotensin‐converting enzyme inhibition therapy and digoxin and application of dietary and rehabilitative services. Patient knowledge was assessed by questionnaire. Results: Eighty patients were included in this study. Two‐thirds of the population had impaired systolic function. The majority of patients were managed by internal medicine physicians, and this population was older and more likely to have normal systolic function. Prescription of converting enzyme inhibitor therapy was more frequently used in cardiology‐managed patients (96 vs. 70%, P<0.05). Neither group applied dietary or rehabilitative advice to a significant level. Patient comprehension was poor, especially with regard to understanding of medicine and the value of weight measurement.ConclusionThe above data demonstrate a lack of use of rehabilitative and dietary services and poor patient knowledge. These deficiencies may play a role in determining outlook and may impede the expected improvement in prognosis that has been witnessed in large randomised studies.
Estimation of Solvent‐Modulated Linear Adsorption Parameters of Taxanes from Dilute Plant Tissue Culture Broth
Authors: Ma Zidu , Tanzil Dicksen , Au Bob W. , Wang Nien‐Hwa L. 
Published: July 2002

AbstractA stepwise elution technique is developed to estimate the linear solvent‐modulated isotherm parameters of taxanes from dilute plant tissue culture broth. The technique is proven to be robust under various experimental conditions because mass transfer effects are decoupled from isotherm effects on elution bands. Simple algebraic equations are derived to relate isotherm parameters to the retention times at different solvent compositions in stepwise elution under volume overload conditions. A minimum loading volume, which is a function of mass transfer parameters, column geometries, and adsorption affinities, is estimated from moment analysis to ensure that band spreading due to mass transfer does not affect the accuracy of this method. The isotherms of a low‐cost solute, phenylalanine, under different ethanol concentrations are measured by a standard multiple frontal chromatography method. The results serve as benchmarks for the parameters that are estimated over the same ethanol concentration range using the stepwise elution technique. The parameters determined from these two independent methods are in close agreement. For paclitaxel and cephalomannine, the retention times and peak shapes from plant tissue culture broth experiments are well predicted from rate model simulations using the parameters estimated from single‐component elution data.
Microbial Synthesis of 3‐Dehydroshikimic Acid: A Comparative Analysis of d‐Xylose, l‐Arabinose, and d‐Glucose Carbon Sources
Authors: Li Kai , Frost J. W. 
Published: July 2002

Abstract3‐Dehydroshikimic acid is a hydroaromatic precursor to chemicals ranging from l‐phenylalanine to adipic acid. The concentration and yield of 3‐dehydroshikimic acid microbially synthesized from various carbon sources has been examined under fed‐batch fermentor conditions. Examined carbon sources included d‐xylose, l‐arabinose, and d‐glucose. A mixture consisting of a 3:3:2 molar ratio of glucose/xylose/arabinose was also evaluated as a carbon source to model the composition of pentose streams potentially resulting from the hydrolysis of corn fiber. Escherichia coli KL3/pKL4.79B, which overexpresses feedback‐insensitive DAHP synthase, synthesizes higher concentrations and yields of 3‐dehydroshikimic acid when either xylose, arabinose, or the glucose/xylose/arabinose mixture is used as a carbon source relative to when glucose alone is used as a carbon source. E. coli KL3/pKL4.124A, which overexpresses transketolase and feedback‐insensitive DAHP synthase, synthesizes higher concentrations and yields of 3‐dehydroshikimic acid when the glucose/xylose/arabinose mixture is used as the carbon source relative to when either xylose or glucose is used as a carbon source. Observed high‐titer, high‐yielding synthesis of 3‐dehydroshikimic acid from the glucose/xylose/arabinose mixture carries significant ramifications relevant to the employment of corn fiber in the microbial synthesis of value‐added chemicals.
In Vivo and In Vitro Investigations on the Synthesis of Estradiol‐17β by the Bovine Mammary Gland near Term
Authors: Janowski T , Zdunczyk S , Mwaanga ES , Babinski J , Ras A 
Published: July 2002

ContentsConcentration of estradiol‐17β in the milk and tail vein were determined by radio‐immunoassay in 40 dairy cows from day 20 prepartum to day 4 postpartum. The animals were divided into two groups according to their milk production in the previous lactation: group 1 (n = 20)‐high‐yielding cows (6500 kg milk per lactation), group 2 (n = 20) low yielding cows (3700 kg milk per lactation). The levels of estradiol‐17β were higher (p 0.01) in the milk vein than in the tail vein from about day 12 prepartum to parturition. In comparison with low‐yielding cows the high‐yielding cows had significantly higher (p 0.01) estradiol‐17β values in the mammary venous plasma, but not in peripheral plasma. In an in vitro experiment, homogenates of bovine mammary tissue collected on day 7 prepartum from two cows were incubated with 3H‐androstendione. After incubation the samples were extracted and 3H‐estradiol‐17β was separated by high‐performance liquid chromatography. Radioactivity of fractions containing 3H‐estradiol‐17β was determined and calculated as a percentage of total radioactivity. Androstendione was metabolized into estradiol‐17β to the extent of 37%. These results indicate that the mammary secretion of estradiol‐17β starts about day 12 prepartum and is associated with milk yield. Furthermore, the results of a preliminary in vitro study with a limited number of animals suggest that the bovine mammary tissue is able to synthesize estradiol‐17β near term.
Computed tomography pulmonary angiography with pelvic venography in the evaluation of thrombo‐embolic disease
Authors: Au Virginia Wk , Walsh Geraldine , Fon Gerald 
Published: July 2002

SUMMARYA prospective study was performed to evaluate the usefulness of CT pelvic venography (CTV) in the detection of pelvic vein thrombosis in patients referred for CT pulmonary angiography (CTPA) for suspected pulmonary embolism. Fifty consecutive patients referred for CTPA had CTV performed at the time of CTPA. All patients had duplex ultrasound (DUS) of the lower limb veins for evaluation of deep venous thrombosis (DVT) within 24 h of the CT study. Twelve (24%) of the 50 patients had pulmonary embolism diagnosed on CTPA. Associated DVT was detected in six of these patients; two cases were detected by CTV alone, while one case was detected by both CTV and DUS. The remaining three cases had DVT diagnosed by DUS alone. In the 38 patients with a negative CTPA, three patients had venous thrombus diagnosed by CTV. Of these three patients, two had a negative DUS study. CTV therefore led to a definitive imaging diagnosis of thrombo‐embolic disease in two (4%) more patients. CTV adds little time and cost to the CTPA examination and leads to a moderate increase in definite imaging diagnosis of thrombo‐embolic disease.
Magnetic resonance imaging signal characteristics in hydatid cysts
Authors: Singh Surendra , Gibikote Sridhar V 
Published: July 2002

SUMMARYThe MRI features of hydatid cysts were retrospectively studied in 12 patients to look for specific signal characteristics. Twelve patients in the series included eight with abdominal, two with abdominal‐pelvic, one with a sacral and one with a lung hydatid cyst. The T1‐, T2‐ and proton density (PD)‐weighted images of spin‐echo sequence were used for imaging. The signal characteristics of the hydatid parent cyst capsule and fluid, daughter cyst fluid, detached germinal membrane and surrounding soft tissue reaction were noted. Observations revealed that the capsule is best seen on T2‐ and PD‐weighted images. The daughter cysts are best demonstrated on T1‐weighted images, whereas the difference in the signal intensities of parent cyst and daughter cyst fluid is better demonstrated on T2‐weighted and T1‐weighted images, and the detached germinal membrane is best seen on T2‐ and PD‐weighted images. The signal characteristics of hydatid cyst morphology can help distinguish it from other entities.
A systematic review of foot ulcer in patients with Type 2 diabetes mellitus. I: prevention
Authors: Mason J. , O’Keeffe C. , McIntosh A. , Hutchinson A. , Booth A. , Young R. J. 
Published: July 2002

Summary Aim To evaluate the role of preventative strategies in reducing foot ulcers in patients with Type 2 diabetes mellitus, both in the general population and those identified to be at a raised risk. Method A systematic review of interventions to prevent diabetic foot ulcers. Results Available studies are generally unsatisfactory in their ability to answer the important questions relating to prevention. However, where people with diabetes receive well‐organized and regular care with rapid referral to appropriate specialist multidisciplinary teams when problems (or their precursors) occur, ulcer morbidity can be substantially reduced. Conclusion Foot ulcers are common in people with diabetes and are costly in terms of both patient morbidity and the use of healthcare resources. Although it is nearly a decade since the St Vincent Declaration called for a marked reduction in morbidity to be achieved through better patient management, available evidence suggests that the process of care in Britain is still very variable in quality. Foot care for people with diabetes must be organized to provide monitoring, education and referral in a manner acceptable to patients and realistic for local healthcare providers.
The increasing prevalence of allergy: a challenge for the physician
Authors: Mösges R. 
Published: July 2002

SummaryThe prevalence of allergic disorders has increased markedly throughout the world during the past three decades. There has been considerable controversy about the extent to which the increase is real, or attributable to increased awareness or better diagnosis. It seems probable that the increased prevalence is real because longitudinal studies have shown a rapid exponential increase in allergic disorders such as asthma. Since there is a marked difference in the occurrence of allergic disorders between Western and less developed countries, as well as between rural and urban areas, it is likely that environmental (‘lifestyle’) factors are aetiologically involved. It also seems probable that contact with microbial antigens, in the form of childhood infections, vaccinations and contact with farm animals, can exert some protection against the later development of allergies. Studies are in progress to determine whether reduction in risk factors or intervention with anti‐allergic therapies can modify the long‐term outcome in populations at high risk.