bluuebunny/crossref_metadata_2025_split huggingface dataset:
Boiling point estimation of 1-butanol and nitromethane by the viscosity- temperature dependence study of corresponding binary fluid systems
Authors: Kouissi T. , Salhi H. , Dallel M. , Messaâdi A. , Akhtar S. , Ouerfelli N. , Toumi A. 
Published: December 2022

Abstract
Calculation of excess quantities in 1-butanol + nitromethane binary mixture (from 303.15 to 323.15) K from experimental shear viscosity and density values were depicted in the previous work. Investigations of these experimental values to test correlation quality of various equations and their corresponding relative functions were also reported. Taking the quasi-equality between the enthalpy of activation of viscous flow ΔH* and the molar activation energy Ea into account, we can define partial activation energy Ea1 and Ea2 for 1-butanol with nitromethane respectively together with their individual contribution separately. Correlation between Arrhenius parameters brings fourth interesting Arrhenius absolute temperature in comparison with the absolute temperature of vaporization in the fluid vapor equilibrium, and the limited corresponding partial molar quantities that can allow us to anticipate the value of the boiling points of the pure constituents. New empirical equations to indicate the boiling absolute temperature are suggested.
The validation and refinement of a Work Readiness Scale for graduate Allied Health Professionals
Authors: Lawton Vidya , Ilhan Emre , Pacey Verity , Jones Taryn M , Walker Arlene , Dean Catherine M 
Published: December 2022

AbstractThe transition for allied health graduates from university to the workforce has been perceived to be difficult and overwhelming, leading to early attrition within healthcare professions. Work readiness is a crucial aspect of successful transition to the workforce, however the elements of work readiness are not clearly defined. The 62-item Work Readiness scale for Allied Health Professionals (WRS-AH), based on a Work Readiness scale for a generic population of graduates, has yet to be validated. The aim of this study was to validate and refine the WRS-AH and compare the results to the original four factor construct. Participants were 245 Australian allied health professional graduates who completed the WRS-AH. An exploratory factor analysis supported a four-factor solution with domains (interpersonal capabilities, practical wisdom, personal attributes, and organisational acumen) similar to the original WRS. The final WRS-AH had 32 items, demonstrated good reliability, and explained 38% of the total variance. Using the refined scale, on average, the Australian allied health graduates reported an overall work readiness score of 80% (SD 8) with the scores highest for practical wisdom (Mean 90%, SD 8) and lowest for personal attributes (Mean 65%, SD 14). This study supports a valid and reliable scale to measure the perceived work readiness of allied health graduates as they transition from university to the workforce. The WRS-AH confirms that work readiness is multi-dimensional and may provide a more targeted approach to interventions to improve work readiness in future allied health professional graduates.
PCMT1 has Potential Prognostic Value and Promotes Cell Growth and Motility in Breast Cancer
Authors: Lin Yi-Wei , Wu Fang-Cai , Zhuang Yi-Xuan , Chu Ling-Yu , Ding Tian-Yan , Qu Qi-Qi , Li Xin-Hao , Cui Yu-Kun , Hong Chao-Qun 
Published: December 2022

Abstract
Breast cancer (BC) is one of the frequently diagnosed cancers, and the leading cause of cancer-related death among women worldwide. The roles of protein L-isoaspartate (D-aspartate) O-methyltransferase (PCMT1) in human cancer have been exploring, but the clinical significance and biological function of PCMT1 in BC are not yet clear. In this study, based on the TCGA-BRCA data set, the results showed that high expression of PCMT1 gene was significantly correlated with shorter overall survival (OS), disease specific survival (DSS) and progress free suvival (PFS) of BC patients. Utilizing the immunohistochemical assay, we found that PCMT1 protein was located in the cytoplasm of BC cells, and PCMT1 expression was only obviously correlated with progesterone receptor expression of patients (p < 0.05). Survival analysis showed that PCMT1 protein high-expression was an independent unfavorable prognostic factor for BC patients. The in vitro experiments revealed that PCMT1 could regulate growth, migration and invasion capacity of MCF-7 cell, and modulate the expression of AKT/GSK3β/mTOR signaling pathway, EMT and cell cycle-associated protein. In conclusion, PCMT1 was a potential unfavorable prognostic biomarker for BC patient and might influence the AKT/GSK3β/mTOR signaling pathway to regulate the growth and motility of MCF-7 cell.
Dual orexin receptor antagonists and Tgn-020 affect learning and memory in 8-mth-old APP / PS1 (AD) mice
Authors: Zhou mengzhen , Li Yaran , Tang Shi 
Published: December 2022

Abstract
Objective: To explore which dose of Dual orexin receptor antagonist (DORA, using Almorexant) can improve mouse sleep without damaging mouse learning and memory, and whether there are serious adverse effects. Explore whether AQP4 blockers (TGN-020, abbreviated TGN) can affect Aβ deposition.
Methods: divided into two rounds of experiment, 71 mice were randomly divided into 6 groups in addition to the control group 8,11 mice, the first round of DORA injection 10mg / kg group, 30mg / kg and 60mg / kg group mice, intraperitoneal injection for 28 days, while monitoring sleep, 28 days of Y maze and water maze experiment, behavioral experiments after death of mice, immunohistochemistry. A second round of experiments was followed by the TGN + 30 group of TGN (AQP4 blocker) and 10mg / kg blocker) and TGN+ 30mg / kg of DORA.
Results: The total sleep time of each group was statistically significant compared with the control group (10mg / kg: 12:6 minutes; 30mg / kg: 14:27 minutes; 60mg / kg: 16:57 minutes, P <0.001). With control mice (hippocampal area 0. 181 ± 0.05, Cortical Area 0.185 ± 0.07) compared to, 10mg / kg (hippocampus 0.177 ± 0.07, Cortical Area 0.155 ± 0.05), 30mg / kg (hippocampus 0.145 ± 0.05), 0.137 ± 0.05) in the Cortical area. The group of mice showed reduced A β 42 plaques in the hippocampus and cortex, The difference in plaque deposition area was statistically significant; In contrast to the con group of mice, The 60mg / kg group (hippocampus 0.106 ± 0.06, Cortical area 0.113 ± 0.06) The mice have the smallest area of the Aβ42 plaques corresponding to the brain areas, The difference was statistically significant. The percentage of free alternation experiments was decreased in TGN group mice and increased in TGN + 30 group mice as compared with the control mice. The percentage of experiments with free alternation in the TGN and TGN + 30 groups was 0.31 ± 0.10 and 0.35 ± 0.16, respectively.
Conclusion: DORA intervention mice have good sleep response and little residual effect, DORA intervention can improve the working memory of APP / PS1 mice; DORA can reduce Aβ deposition, slow down the neurodegeneration of Alzheimer's disease, TGN will increase Aβ deposition; 30mg / kg may be the best dose of Almorexant, can prolong sleep duration without damaging learning and memory; TGN can aggravate neurodegeneration, and damage the learning and memory of APP / PS1 mice.
Polyamide 6.6/Bismuth (III) Oxide Electrospun Nanocomposites for Potential Applications in Electronics
Authors: AYGÜN Hayriye Hale , ALMA Mehmet Hakkı 
Published: December 2022

Abstract
In this study, it is aimed to observe electrospinnability of bismuth oxide (Bi2O3) microparticles via polymer solution and effect of loading on electrical insulating property of electrospun composite structure. For that purpose, polyamide 6.6 polymer (PA6.6) with high dielectric constant was loaded with bismuth oxide microparticles and it was used for coating polyester spunbonds by electrospinning technique. Morphological properties, thermal behaviors and electrical resistance of coated spunbonds were investigated. Scanning electron microscopy (SEM) and electron dispersive X-ray spectroscopy (EDX) showed that Bi2O3 was succesfully adapted into fiber structure and nano-scale PA6.6/Bi2O3 composite fibers were obtained. Thermal behaviors of coated samples were developed by increasing Bi2O3 loading according to differential scanning calorimetry (DSC) and thermogravimetic analysis (TGA) results. Addition of Bi2O3 caused remarkable increase on electrical resistance of PA6.6 electrospun surfaces. Bi2O3 /PA6.6 nanocomposite fibers are promising and good candidates for thin electrically insulating polymer-based structures for micro- or nanodimensional devices.
Association of nitrogen use efficiency in diverse rice genotypes with sustenance of reproductive stage photoassmilation and nitrogen metabolism
Authors: B Jagadhesan , Meena Hari Singh , Jha Shailendra K , KG Krishna , Kumar Santosh , A Elangovan , Chinnusamy Viswanathan , Kumar Arvind , Sathee Lekshmy 
Published: December 2022

Abstract
To maintain yield stability and environmental sustainability of rice cultivation, improvement in nitrogen use efficiency (NUE) is essential. We identified rice genotypes showing high NUE in control (N120) and N deficient (N0) field conditions by analyzing NUE parameters and different contributing traits. In the first season, genotypes BAM-3181, BAM-4797, BAM-3154, NL-26 IR-83929-B-B-291-3-1-1 (IR-3-1-1), APO and NERICA-L-42 showed high biomass, panicle yield and N utilization efficiency (NutE) at low N field conditions. Reproductive stage N assimilatory and signaling gene expression was correlated to the variation in NUtE. The sequence variation in N metabolism and signaling (NLP) genes were analyzed in selected genotypes (APO and NERICA-L-42). Significant non-synonymous SNPs were found in NPF2.2, PTR2, NGR9 (DEP1), Fd-GOGAT, NLP3, NLP4 and NLP5 genes of APO, NERICA-L-42 and w.r.to japonica genotype Nipponbare. The significant variation in reproductive stage gene expression and changes in amino acid sequence of NLP3, NLP4, NLP5 among rice genotypes differing in NUE is an unexplored and potent genome editing target for high NUE in rice. The non-synonymous SNPs identified in the study will be important genomic resources for improving rice NUE.
Love Canal: Health Effects and Clean Up Costs
Authors: Zelalem Mengistu 
Published: December 2022

Abstract
The Love Canal is a hazardous waste dump-site located in the center of a middle class community in Niagara Falls, New York" which was used as municipal and chemical waste disposal area for residue from the manufacture of chlorinated hydrocarbons from the 1920s until 1953 when it was covered with earth. Perhaps because they didn’t understand the potential risks associated with Hooker’s chemical wastes primary schools and homes had been constructed around the canal .The tragedy of Love Canal were damaged countless families and ruined the environment for many years. The toxic contamination found throughout the soil brought emotional as well as physical pain to those who had purchased homes in the Love Canal area or who had sent their children to its school system. The various additional substances discovered at Love Canal produce a range of acute, sudden symptoms as well as chronic or long term health problems. Proper disposal of hazardous waste is important in protecting the public health. Site selection and site preparation are important factors to be considered for hazardous waste disposal. Overall, the chemical cleanup process is time consuming and costly and this is why it is so important to dispose of toxic waste in proper facilities where the substances will not come into contact with people and pollute their land and water supplies.
Example elements of programming based on construction of interactive appliction for lathe operators training.
Authors: Filipek Dariusz 
Published: December 2022

Abstract
The paper presents examplary solutions of programming based symulator project of conventional lathe. This symulator was elaborated in Central Institute for Labour Protection – National Research Institute. Symulator as a part of test stand for interactive handling of Lathe is suporting and suplemenary training tool . This tool serves to improving of safe handling machines of this type.
PENYULUHAN VAKSINASI COVID-19, PERSIAPAN PRE VAKSIN DAN TINDAKAN PASCA VAKSIN
Authors: Probowati Wiwiek , Jayadi Tejo , Rustam Brenda Miriane , Putri Agatha Maheswari Adita 
Published: December 2022

Abstrak

Intisari : Pada April 2021 kasus covid di Indonesia sebanyak 1.69 juta, dengan jumlah kesembuhan adalah 1.35 juta dan meninggal sebanyak 40.858 kasus. Angka ini tidak dapat dianggap sebagai angka yang kecil, Indonesia masuk dalam urutan ke-18 negara dengan kasus covid-19 tertinggi dan nomor 1 tertinggi di Asia tenggara. Pada tanggal 13 Januari 2021, Indonesia resmi memulai pemberian vaksin kepada masyarakat, namun pemberian vaksin gratis oleh pemerintah ini masih mendapatkan pertanyaan dan penolakan dari masyarakat.
Tujuan : Meningkatkan pemahaman masyarakat terhadap pentingnya vaksinasi Covid-19, mengenal beberapa keadaan yang menjadi kontraindikasi pemberian vaksinasi Covid-19 dan penatlaksanaan apabila terjadi Kejadian Ikutan Pasca Imunisasi (KIPI)
Metode : Penyuluhan dan Diskusi derta mengevaluasi pemahaman masyarakat dengan pre test dan post test yang dilakukan oleh masyarakat desa Miliran.
Hasil evaluasi : edukasi dan diskusi terkait vaksinasi Covid-19 di desa Miliran mampu mengubah paradigma masyarakat terhadap vaksinasi Covid-19 untuk bisa menerima vaksinasi covid-19 dengan baik. Penyuluhan di desa Miliran ini mendapatkan respon positif masyarakat dengan peningkatan nilai postes dan bangkitnya keinginan masyarakat dalam menyebarluaskan kesadaran melkukan vaksinasi Covid-19.

Kata kunci : Covid-19, Penyuluhan, Vaksin
BUTIK SAMPAH MINI-WORKSHOP UNTUK MENGURANGI LIMBAH PAKAIAN MENJADI KERAJINAN TAS
Authors: Arsanti Vidyana , Sekarsih Fitria Nuraini 
Published: December 2022

Meningkatnya kesejahteraan akan diikuti dengan pola hidup yang semakin konsumtif. Hal ini berkontribusi terhadap jumlah sampah yang dihasilkan terutama limbah pakaian. Kondisi ini, menggerakkan tim Amikom bersama Faskel Bener, Bapak Lurah, pengurus BERAMAL (Bener Ramah Lingkungan), Ketua Rukun Warga dan Ketua Pokja IV PKK membuat inovasi pengelolaan sampah. Kegiatan ini berlokasi di Kalurahan Bener dengan mengerahkan partisipasi masyarakat. Tujuan kegiatan ini adalah mengatasi permasalahan limbah pakaian sekaligus meningkatkan kualitas lingkungan. Hasil dari kegiatan masyarakat ini adalah kegiatan pelatihan mengubah limbah pakaian menjadi kerajinan tas. Luaran dari kegiatan masyarakat ini berupa peningkatan skill ketrampilan para pengurus bank sampah untuk mengatasi limbah pakaian dan menambah pendapatan dari hasil penjualan tas. Selain itu kerajinan Daur Ulang Sampah juga sudah dibuat video tutorial pembuatannya. Kesimpulan dari kegiatan ini: (1) Limbah pakaian dapat digunakan untuk membuat produk turunan lain (recycle) salah satunya adalah tas rajut. (2) Dibutuhkan waktu sekitar 2 jam untuk peserta belajar merajut produk pakaian ini. (3) Nilai produk limbah pakaian tersebut dapat bernilai jual sehingga dapat meningkatkan ekonomi masyarakat.

Kata kunci: butik sampah, kerajinan tas, limbah pakaian, mini workshop, recycle
COMPARISON OF MOTOR PERFORMANCE BETWEEN CHILDREN WITH MULTIPLE DISABILITIES AND TYPICAL DEVELOPMENT
Authors: GÜVEN Zeynep , YILDIZ KABAK Vesile , DEMİRCİOĞLU KARAGÖZ Arzu , ÇEVİK Nurcan , ATASAVUN UYSAL Songul 
Published: December 2022

Purpose: Individuals with multiple disabilities have two or more disabilities at the same time, and these impairments can cause qualitatively and quantitatively insufficient motor performance. This study aimed to compare the motor performance of children with multiple disabilities to children with typical development.
Methods: This prospective study included 26 children with multiple disabilities who had visual impairment according to the International Statistical Classification of Diseases and Related Health Problems: 11th Revision, and 20 children with typical development. The Bruininks-Oseretsky Test of Motor Proficiency Second Edition Short Form was used to examine motor proficiency. A standard hand dynamometer and pinchmeter were used to assess hand and finger grip strength. The Nine-Hole Peg Test was used to evaluate performance-based hand functions.
Results: Children with multiple disabilities had lower scores for balance control (p
THE RELATIONSHIP BETWEEN TRUNK MUSCLE STRENGTH AND PELVIC OSCILLATION IN ASYMPTOMATIC PHYSICALLY INACTIVE ADULTS
Authors: ZORLULAR Ali , AYGUN POLAT Elif , KAFA Nihan , ATALAY GÜZEL Nevin 
Published: December 2022

Purpose: Pelvis and trunk structure are body segments that are integrated with each other. Collaboration between pelvic mobility and trunk muscles plays a significant role in walking and energy consumption. The aim of this study is to investigate the relationship between trunk muscle strength and pelvic oscillations.
Methods: Twenty-eight healthy individuals volunteered for the study (16 women, 12 men; mean age 24.46 ± 2.97 yrs., height 172.03 ± 9.41cm, weight 67.78 ± 16.31 kg). Pelvic oscillations were measured by using a wireless tri-axial accelerometer. Trunk muscle strength was evaluated with Isokinetic Dynamometer (Cybex Humac Norm Testing & Rehabilitation System, USA). The trunk extensors and flexors were tested concentrically at 60°s. Statistically, the direction and level of the relationship were examined by using Spearman Correlation Analysis.
Results: Correlation analysis showed significant relationships between concentric strength of trunk flexion and anterior-posterior pelvic tilt (r=-0.419 p
Urinary Incontinence and Quality of Life in Women With Cystic Fibrosis
Authors: Soares Marinice Nunes , Paiva Luciana Laureano , Dalcin Paulo de Tarso Roth , Ziegler Bruna 
Published: December 2022

Introduction:
Stress urinary incontinence (SUI) is recognized as a common complication in women with CF.

Objective:
The primary objective of this study was to verify the prevalence of urinary incontinence (UI) and its associations with quality of life (QoL) in adult women with CF. The secondary objective was to identify possible associations of UI with cough score, nutritional parameters, and pulmonary function.

Methods:
This cross-sectional study included female patients aged 18 years and older. All patients answered the International Consultation on Incontinence Questionnaire Short Form, the Kings Health Questionnaire, and the Leicester Cough Questionnaire. Nutritional assessment was obtained. Sputum bacteriology and lung function were also performed.

Results:
Fifty-two women were included, with mean age of 29.0±9.7 years and mean forced expiratory volume in one second (FEV1) of 50.1±21.7% of predicted. Thirty-two patients (61.5%) presented symptoms of UI, 23 (44.2%) of stress UI and 9 (17.3%) of mixed UI. However, there was no significant association between UI and pulmonary function, sputum bacteriology, and cough score (p>0.05). There was a significant association between UI and QoL variables (p<0.05).

Conclusion:
This study identified a prevalence of 61.5% of UI in women with CF. The presence of UI in women with CF resulted in a negative impact on QoL.
Acute Pericarditis as the Primary Presentation of COVID-19 Infection followed by Guillain-Barre Syndrome in a Healthy Young Man: A Case Report
Authors: Noghabaei Giti , Arab Maliheh , Payami Sara , Ghavami Behnaz 
Published: December 2022

Background:
Symptomatic COVID-19 infection most often presents as acute respiratory distress syndrome. Acute pericarditis and Guillain–Barré syndrome are rare extrapulmonary manifestations of this infection.

Case Presentation:
A 27-year-old man presented with chest pain, with negative troponin and typical electrocardiographic findings, resulting in a diagnosis of acute pericarditis. He had no respiratory symptoms, nor the chest computerized tomography (CT) scan findings of COVID-19, and his Polymerase chain reaction (PCR) was negative. One week later, he developed clinical symptoms of Guillain-Barre syndrome, along with respiratory manifestations of COVID-19. His repeat chest CT scan and PCR test confirmed COVID-19 infection. After 17 days of hospital stay, he improved clinically and was discharged.

Conclusion:
This is the first case of acute pericarditis as the primary presentation of COVID-19 in the absence of respiratory symptoms and a clear chest CT scan, followed by the development of Guillain–Barré syndrome and respiratory tract manifestations of COVID-19. Clinicians should be aware of the extrapulmonary presentation of COVID-19 infection.
In-silico Identification of Novel Drug Target for Osteoarthritis using Network Biology Approaches
Authors: Shukla Nityendra , Srivastava Neha , Trivedi Aditya , Seth Prahlad Kishore , Srivastava Prachi 
Published: December 2022

Osteoarthritis (OA) is a degenerative joint disease which is the leading cause for physical disability among the adult population and yet the mechanisms responsible for the development and progression are not well understood. Since it has no curative solutions, treatment is limited to symptomatic targeting and improving quality of life. There is a lack of disease-modifying therapeutics and non-surgical intervention options to prevent the progression of disease. Risk factors range from systemic (e.g. age, sex, genetics, obesity) to biochemical (e.g. joint injury, muscle weakness, sport). The prevalence of OA is ever increasing due to the ageing global population and the obesity epidemic. Since OA exhibits strong genetic predisposition and a complex pathogenesis, we applied an in silico network biology approaches to identify a candidate gene using a protein-protein interaction (PPI) network of OA, which may be an important aspect of disease pathogenesis and assist us in furthering our understanding of the development and progression of the disease as well as identify a drug-lead for the treatment of joint-pain associated with OA and improving quality of life in patients without lasting side effects. Our findings suggest that phytochemical
compounds may be promising candidates for multi-target application against OA and will assist in development of new molecules.
Population Exposure to Particulate Matter and COVID-19: An Ecological Study for Health Promotion
Authors: Sarmadi Mohammad , Rahimi Sajjad , Arefi Maryam Feiz , Aghabeigi Arash , Yektay Sama , Sanaei Daryoush 
Published: December 2022

Background:
Documentation of the association between ambient pollution and severe coronavirus disease 2019 (COVID-19) infections are complicated and vague.

Objective:
This short research investigated the distribution of COVID-19 and its association with particulate matter before mass vaccination.

Methods:
We used the reported cases and deaths per capita and PM2.5 (particulate matter ≤ 2.5 μm) in 245 cities in the United Kingdom (UK) and United State, of America (USA) based on publicity available secondary data. We performed correlation and regression analysis between variables to explore the association between COVID-19 and PM2.5.

Results:
The analysis revealed that PM2.5 positively correlated with cases (Unstandardized Coefficient (b):150.04, P=0.006) and deaths per capita (b: 3.87, P=0.005) in total cities, after adjusting for median age and population density.

Conclusion:
The findings showed that the distribution of the disease may be affected by the PM2.5 concentration.