bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of rehabilitation support on male and female after intertrochanteric femoral fracture treatment
Authors: BAŞAR Betül 
Published: January 2022

Aim: The aim of our study is to investigate the effect of rehabilitation support after intertrochanteric femur fractures on men and women. The results of the groups consisting of male and female patients who received and did not receive rehabilitation support were compared both between the same sexes and between different sexes.
Material and Method: One hundred twenty four patients were evaluated under two groups according to whether they received rehabilitation support or not. First group (no rehabilitation support) consists of 42 females, and 29 males, and second group (rehabilitation support) consists of 30 females, and 23 males. While the patients in the first group performed the exercises themselves at home, the patients in the second group received rehabilitation support under the guidance of a physiotherapist. The patients in both groups were also evaluated under 2 subgroups as male and female.
Results: There was no significant differences between both groups in terms of mean age, female male ratio, fracture type, mean follow-up time, Harris hip score, Barthel life index, Parker and Palmer Mobility Scale before fracture. There was also no significant difference between the subgroups of the both groups. Harris hip score, Barthel life index, and Parker and Palmer Mobility Score of males were better than females at the final follow-up in the first group. The results of females were worse than pre-fracture, but there was no difference in males at the final follow-up. Harris hip score, Barthel life index, and Parker and Palmer Mobility Score of males were better than females at the final follow-up in the second group as first group. While the results of females were not different compared to pre-fracture, the results were better in males at the final follow-up. When the female and male subgroups of both groups were compared with each other, it was determined that the results in male and female subgroups in the 2nd group were significantly better.
Conclusion: The continuity of rehabilitation support after hospital discharge is very important. Although rehabilitation support positively affects the results in male and female, it is much more important for female than male.
Primary bone tumors and tumor-like lesions of the wrist: a single-center experience
Authors: SOFULU Ömer 
Published: January 2022

Aim: The incidence of primary bone tumors of the wrist is increasing. The aim of this study was to examine the characteristics, treatment protocols, complication rates, and functional outcomes of bone tumors of the wrist treated in a tertiary orthopedic oncology center.
Material and Method: We retrospectively analyzed 93 patients with bone tumors located in the wrist (63 distal radius, 23 distal ulna, 7 carpal bone) who were operated on between 2005 and 2020. Demographic information was recorded. Functional outcomes were evaluated with the Musculoskeletal Tumor Society System (MSTS) scoring system.
Results: There were 57 male and 36 female patients. The average follow-up period was 32 months (range 16-163). There were 82 benign and 11 malignant lesions. Distal radius was the most common site of involvement. The most common type of benign tumor in the distal radius and distal ulna was the giant cell tumor (GCT; 26 and 10 patients, respectively). Among the malignant tumors in the distal radius, 5 were Ewing sarcoma, and 2 were osteosarcoma. All patients with malignant lesions underwent wide surgical resection and free vascularized fibular graft (FVFG) reconstruction. Of the malignant tumors in the distal ulna, 3 were Ewing sarcoma, and 1 was osteosarcoma. These were treated with wide resection and FVFG reconstruction (n=3) and wide resection and fibular strut graft (n=1). The rarest site for tumors in the wrist was the carpal bones. Carpal bone lesions included scaphoid (n=5) and lunate (n=2) tumors. In all of these patients, pathological examination indicated intraosseous ganglion cysts. The average MSTS score of all patients was 27 (range 24-30). Of the 36 patients with GCT, 4 (11%) developed local recurrence. One patient with Ewing sarcoma developed local recurrence and underwent secondary amputation. Distant lung metastasis was observed in 5 of 8 patients with Ewing sarcoma.
Conclusion: Our study confirmed that bone tumors in the wrist are rare. Most benign tumors can be treated with curettage and cement augmentation. For malignant tumors, it is possible to restore function with FVFG.
Sepsis induced coagulopathy score and D-dimer levels in COVID-19 patients followed in intensive care; what has changed in COVID era?
Authors: AYYILDIZ Ayşe , ÇOBANER Nurdan , YELKEN Birgül 
Published: January 2022

Aim: This study was planned to compare the extent of hypercoagulopathic complications in COVID-19 pneumonia with that of last year's pneumonia cases which consist of by other agents.
Material and Method: The data of patients with pneumosepsis due to non-COVID-19 causes between 01 April-30 June 2019 and COVID-19 pneumosepsis patients between 01 April-30 June 2020,were analyzed retrospectively. Demographic data, comorbidities, SOFA scores, SIC scores, D-dimer levels, coagulopathic complications, mortality and discharge status of patients diagnosed with pneumosepsis and treated in both periods were recorded
Results: While sequential D-dimer measurements did not show a significant change in the 2019 group, it was observed that it increased significantly in the 2020 group (p
Temporal change of ventricular repolarization indices and index of cardioelectrophysiological balance (iCEB) during COVID-19 treatment including hydroxychloroquine at a tertiary referral hospital
Authors: ÇELİK Çaşıt Olgun , ÇIFTCI Orçun , ULUBAY Gaye , MÜDERRİSOĞLU Haldun 
Published: January 2022

Aim: Hydroxychloroquine (HCQ) is widely administered to patients with confirmed or suspected COVID-19. It may increase the risk of cardiac arrhythmias associated with QT and QTc prolongation. This study aimed to assess the change in iCEB, a new marker of drug-induced arrhythmia, and other repolarization parameters in suspected COVID-19 patients treated with short-course HCQ.
Material and Method: This was a retrospective cross-sectional study including 40 patients hospitalized with suspected COVID-19 according to the CT findings and treated with HCQ. Serial assessments of the QT and QTc intervals and the calculation of the index of cardio-electrophysiological balance (iCEB) were performed using standard 12 lead electrocardiogram before hydroxychloroquine treatment, on the second day of HCQ treatment, and after the day of the last administered dose.
Results: QT, QTcB, QTcF, iCEB, iCEBcB significantly increased on the second day of HCQ treatment compared to baseline (p=0.009, p=0.001, p=0.002, p=0.047, p=0.05, respectively). Similarly, QT, QTcB, QTcF, iCEBcB and iCEBcF were significantly higher on the fifth day compared to baseline (p=0.011, p=0.005, p=0.005, p=0.013, p=0.028, p=0.024 respectively). However, there were no differences between the second and the fifth days of treatment for any of the studied parameters.
Conclusions: QT, QTc, and iCEB significantly increased compared to baseline on the second day, and remained increased on the fifth day of treatment. The differences were attributed to the amount of loading dose and the duration of HCQ treatment. Our study suggests that, along with other ECG markers, iCEB can be used in COVID-19 patients treated with HCQ.
Real-life data of patients with hypoparathyroidism: a case-control study
Authors: TAN Vedat , TUZCU Alparslan Kemal , PEKKOLAY Zafer 
Published: January 2022

Objective: This study aims to investigate real-life data of patients with hypoparathyroidism.
Material and Method: This retrospective case-control study was carried out in a tertiary endocrine center between 1 January 2010 and 31 December 2019. Patients with a confirmed diagnosis of persistent hypoparathyroidism and healthy controls were included. Demographic characteristics of the patients, laboratory findings, etiologies of hypoparathyroidism, treatments they received, reasons for hospitalization, and complications were investigated.
Results: Sixty-five patients (mean age 42.80±13.4 years, 91% female) with hypoparathyroidism, and 54 healthy controls (mean age 33.58±11.9 years, 65% female) were included. Mean calcium level 7.95±0.92 mg/dl, and mean PTH level 9.99±6.30 pg/ml in hypoparathyroidism. Regarding the etiology of HypoPT, 51 (78%) patients had hypoPT due to surgery; 14 (22%) patients developed HypoPT due to non-surgical causes. In patients with hypoPT who underwent surgery, the mean calcium value was 8.03±0.93 mg/dl; the mean calcium value in patients with non-surgical HypoPT was 7.67±0.85 mg/dl. The mean PTH levels in non-surgical group, other group 10.16±6.21 pg/ml and 9.36±6.82 pg/ml, respectively. The most common surgery was due to multinodular goiter (72%). In 46 percent, the most common treatment was calcitriol 0.5 mcg/day and calcium 2000 mg/day. Nearly half of the patients had treatment non-compliance (46%). Eighteen percent of patients had kidney stones. Forty-three percent of the patients had been hospitalized in the last year. The most common reason for the hospitalization of patients with hypoparathyroidism was hypocalcemia, and the most common reason for this was treatment non-compliance.
Conclusion: In our study, the most common cause of hypoparathyroidism is surgery due to multinodular goiter. The most common reason for hospitalization is treatment non-compliance. Up to one-fifth of patients had kidney stones.
The relationship between non-alcoholic fatty liver disease and breast cancer: a retrospective case-control study
Authors: FIRAT Sevde Nur , DURHAN Abdullah , EREL Serap , ÇULHA Cavit 
Published: January 2022

Aim: Breast cancer is the most common cancer among women and is one of the main causes of death in women. It is known that some metabolic components that are risk factors for non-alcoholic fatty liver disease are also risk factors for breast cancer. The aim of this retrospective cohort study was to show the prevalence of non-alcoholic fatty liver disease breast cancer patients and the effect of non-alcoholic fatty liver disease on breast cancer development through comparisons with a control group with normal mammography.
Material and Method: The study included 108 patients who were operated on for breast cancer in the general surgery clinic of our hospital between January 2015 and December 2018 and who underwent abdominal ultrasound for breast cancer staging. A control group was formed of 102 women with benign breast lesions on routine mammography and who underwent abdominal ultrasound within 6 months before mammography. The prevalence of diabetes, hypertension and hyperlipidemia and body mass indexes were similar in both groups.
Results: In the evaluation of all the study participants, an association was found between non-alcoholic fatty liver disease and breast cancer. In the obese and non-obese subgroups, non-alcoholic fatty liver disease was significantly associated with breast cancer in the non-obese subgroup. [OR 2.67%, 95% confidence interval [95% CI) 1.1-6.0, p=0.020].
Conclusion: Non-alcoholic fatty liver disease was seen to be significantly associated with breast cancer regardless of known risk factors. This relationship there was in non-obese women with NAFLD, but not in the obese group.
Publication rate of oral presentations presented at national pathology congresses, 5-year analysis
Authors: BUĞRA Aytül , BUĞRA Abdul Kerim 
Published: January 2022

Aim: In this study, the contribution of the oral presentations presented at national pathology congresses to the literature was investigated.
Material and Method: A total of 378 abstracts presented at national pathology congresses between 2014-2018 were scanned in PubMed and Google Academic databases. In order to determine whether these abstracts were obtained from thesis studies, they were scanned in the database of the National Thesis Center. The screening was performed simultaneously with the verbal title and authors. The abstracts were examined in terms of the study design, the type of institution where the study was conducted, whether it was a thesis study, the status of its publication in scientific journals, the type of peer-reviewed journal in which it was published, and the time from presentation to publication.
Results: 47.4% (n=179) of 378 papers were retrospective and 52.6% (n=199) were prospective studies. 73.5% (n=278) of the studies of the presentations were done in universities, 23.5% (n=89) in training and research hospitals, and 3% (n=11) in other institutions. 16.9% (n=64) of the abstracts were obtained from the thesis. A total of 27% (n=102) of the abstracts were published in a scientific journal as an article. A significant difference was found in terms of publication in prospective studies compared to retrospective studies (p=0.03). University hospitals had the highest rate (25.5%, n=71). The average period of publication of papers in a scientific journal was 15.0 ±12.3 months (0-68.9) months. 61.8% (n=63) of the abstracts were published in SCI(E) journals, 18.6% (n=19) in other international peer-review journals and 19.6% (n=20) in national peer-review journals.
Conclusion: We believe that researchers should develop not only oral presentation but also encouraging methods to transform studies into publications.
A Tribute to Chief Raphael Ige Ibigbami (1939-2020): The Father of Modern Nigerian Ceramic Art
Authors: Famule Olawole 
Published: January 2022

Awo kìí kú, Awo kìí rùn
Awo ńpa’pòódà ni
B’Áwo bá p’èhìnd ̣ à tán
K’éni máse s ̣ è’dárò Awo
The knowledgeable ones do not die and do not become rotten
They only transition to the spiritual realm of ancestors
Therefore, when a knowledgeable one transitioned
Let no one mourn but rather celebrate the transition
Ìyè ̣rè ̣ Ifá dirge for a deceased Babaláwo, Ifá diviner (‘Father of ancient wisdom’).
We celebrate the life of our knowledgeable and well accomplished retired Ceramics Professor at the Obafemi Awolowo University, Ile-Ife, Nigeria, Chief Raphael Ìgè Ibigbami, who transitioned to the realm of ancestors on August 26, 2020.
TINJAUAN FILOSOFIS IMPLEMENTASI PENDIDIKAN AGAMA ISLAM DALAM PENINGKATAN SISTEM RELIGIUS MAHASISWA UNIVERSITAS SINGAPERBANGSA KARAWANG
Authors: Mursyidin Kafi Nurul 
Published: January 2022

Agama merupakan sumber dari nilai religius dan mempunyai keterkaitan yang sangat erat untuk masuk kedalam jiwa seseorang. Untuk membentuk manusia yang agamis dan mempunyai nilai-nilai religius dalam dirinya diperlukan pendidikan yang terarah. Sebuah lembaga pendidikan hendaknya mengenalkan dan menanamkan tauhid atau akidah kepada peserta didik sebagai pondasi awal sebelum peserta didik mengenal banyaknya disiplin ilmu lainnya. Dengan begitu para guru umunya dan guru pendidikan agama Islam khususnya untuk berupaya menciptakan budaya religius dan meningkatkan potensi religius guna membentuk kepribadian peserta didik menjadi manusia yang beriman, bertaqwa dan berakhlak.
Pertanyaan dan tujuan dalam penelitian ini adalah untuk mengetahui proses implementasi pendidikan agama Islam dalam membangun nilai-nilai religius di lingkungan Fakultas Agama Islam Universitas Singaperbangsa Karawang
Penelitian ini merupakan penelitian lapangan dengan menggunakan pendekatan deskriptif kualitatif. Sumber data yang digunakan dipilih secara purposive dan bersifat snowball sampling. Pengumpulan data dilakukan dengan teknik observasi, wawancara dan dokumentasi. Sedangkan analisis data dilakukan dengan analisis deskriptif.
PENDIDIKAN ANAK DALAM KELUARGA
Authors: Saputra Wisnu 
Published: January 2022

Pendidikan merupakan ladang investasi terbesar dalam membangun dan membentuk manusia seutuhnya. Sentuhan pendidikan mampu membentuk sumberdaya manusia yang beradab dan berkualitas. Keluarga sebagai lembaga pendidikan pertama dan utama bagi anak, karena memiliki peran yang cukup besar dalam mewujudkan cita-cita tersebut. Keluarga sebagai lembaga pendidikan memiliki fungsi yang cukup penting dalam membentuk kepribadian, sosial, sikap keagamaan anak. Karena anak merupakan aset terpenting dalam suatu keluarga, agama dan bangsa. Oleh karena itu, Islam sebagai agama yang rahmatan lil alamin memberikan perhatian dan peraturan dalam pelaksanaan kependidikan di dalam lingkungan keluarga.
Kata Kunci : Pendidikan Anak, Peran Keluarga
Presence of Eroticism in Philippine Short Stories
Authors: RAMOS REYBHOY 
Published: January 2022

This study explored the presence of eroticism in selected Philippine short stories. There were four stories covered such as “The Riddle” by F. Sionil Jose, “The Virgin” by Kerima Polotan Tuvera, “Magnificence” by Estrella D. Alfon, “Midsummer” by Manuel Arguilla, “Dead Stars” by Paz Marquez Benitez and “How My Brother Leon Brought A Wife” by Manuel Arguilla. This literary study has to answer this lone question: What are the manifestations of eroticism, and how is eroticism presented in the different stories? Using qualitative design (focused on content-analysis) with two aid formal and psychoanalytic approaches of interpretation, the study yielded the following findings: The eight stories contained eroticism that revolved around physical attraction towards the opposite sex; love and sex; lust; husband-wife relationship; and physical admiration. Based on the study's findings, the researcher concludes that Eroticism, which manifests in the forms of physical attraction towards the opposite sex; love and sex; lust; and physical admiration, are present in the covered eight Philippine short stories in English. Based on the findings and conclusion of the study, the researchers have to advance the following recommendations: Literature teachers should expose students to various literary pieces of Philippine literature and expose further students to various literary approaches to analyze literary opuses appropriately. Themes on eroticism in Philippine short stories and other genres need to be handled carefully by teachers by allowing students to see the bad side and good side of such themes. Lessons need to be sought after the come up themes for self-reflection. Future researchers are inspired to replicate this study.
Просвітницька діяльність православних братств Волинської губернії (друга половина ХІХ ст.)
Authors: Альошина Оксана 
Published: January 2022

Здійснено аналіз просвітницької діяльності православних церковних братств Волинської губернії у другій половині ХІХ ст. Культурно-просвітницький напрям роботи православні братства реалізовували завдяки проведенню народних безкоштовних читань, поширенню релігійно-моральної літератури, заснуванню церковнопарафіяльних шкіл. Розкрито основні аспекти просвітницької роботи окремих братств, зокрема особливості організації та проведення народних читань. Проведення народних читань мало відбуватися відповідно до законодавчого документу «Правила для проведення народних читань у губернських містах». Члени братств ретельно підбирали тематику лекцій, яка в основному була історичного чи релігійного спрямування. Виконуючи такі завдання, братства ставили собі за мету задовольнити потреби місцевого населення, підняти освітній рівень мешканців міст і сіл Волинської губернії. Представники братств та активні її члени включилися у доволі активну роботу та використовували різні можливості для її реалізації. З’ясовано, що членам православних братств вдалося залучити до участі у народних читаннях значну кількість місцевого населення міст і сіл Волинської губернії.
Prognostic Value and Therapeutic Potential of CBX Family Members in Ovarian Cancer
Authors: Hu Kuan , Yao Lei , Xu Zhijie , Yan Yuanliang , Li Juanni 
Published: January 2022

Background:Ovarian cancer (OV) is one of the common malignant tumors and has a poor prognosis. Chromobox (CBX) family proteins are critical components of epigenetic regulation complexes that repress target genes transcriptionallyviachromatin modification. Some studies have investigated the function specifications among several CBXs members in multiple cancer types, however, little is known about the functions and prognostic roles of distinct CBXs family proteins in ovarian cancer.Methods:In this study, several bioinformatics databases andin vitroexperiments were used to analyze the expression profiles, prognostic values, and therapeutic potential of the CBXs family (CBX1-8) in ovarian cancer.Results:It was found that higher expression of CBX3/8 and lower expression of CBX1/6/7 were detected in OV tissues. CBX2/4/5/8 were significantly correlated with individual cancer stages of OV. The expression of CBX1/2/3 were all significantly associated with worse overall survival (OS) and progression-free survival (PFS) for OV patients, whereas the expression of other five CBXs members showed either irrelevant (CBX5 and CBX8) or inconsistent (CBX4, CBX6, and CBX7) results for both OS and PFS in OV. These results showed that only CBX3 had consistent results in expression and prognosis. Further cell experiments also showed that CBX3 promoted the proliferation of ovarian cancer cells. CBX3 was highly expressed in chemoresistant OV tissues. These results indicated that CBX3 was the most likely prognostic indicator and new therapeutic target in OV. Furthermore, gene enrichment analysis suggests that the CBXs family was primarily involved in mast cell activation and mast cell mediated immunity. Individual CBXs members were associated with varying degrees of the infiltration of immune cells, especially B cells. Finally, a high genetic alteration rate of CBXs family (39%) was observed in OV. The low methylation status of CBX3/8 in OV may be associated with their high expression levels.Conclusions:Taken together, these findings exhibited the pivotal value of CBXs family members (especially CBX3) in the prognosis and chemoresistance of ovarian cancer. Our results may provide new insight to explore new prognostic biomarkers and therapeutic targets for ovarian cancer.
Structural Characterization and Anticoagulant Activity of a 3-O-Methylated Heteroglycan From Fruiting Bodies of Pleurotus placentodes
Authors: Yin Zhen-Hua , Liu Xiao-Peng , Wang Jin-Mei , Xi Xue-Feng , Zhang Yan , Zhao Rui-Lin , Kang Wen-Yi 
Published: January 2022

Pleurotus placentodes, a fungus, belongs to the Pleurotaceae family. The aim of the present study was to characterize the structure of a novel polysaccharide from fruiting bodies of P. placentodes (PPp-W) and evaluate its anticoagulant activity in vitro. The high-performance liquid chromatography and GC–MS analysis indicated that PPp-W with a molecular weight of 27.4 kDa was mainly composed of mannose (17.56%), glucose (6.37%), galactose (44.89%), and fucose (1.22%) with a certain amount of 3-O-methyled galactose. SEM, XRD, and AFM combined with Congo red test revealed that PPp-W was an irregular curly sheet with triple-helix conformation. The FT-IR, methylation, and nuclear magnetic resonance analysis indicated that PPp-W contained→6)-α-D-Galp-(1→, →6)-3-O-Me-α-D-Galp-(1→and →2, 6)-α-D-Galp-(1→ as main chain, partially substituted at O-2 and O-6 by non-reducing ends of β-D-Manp-(1→ and β-L-Fucp-(1→ with a small amount of α-1,3-linked-Glcp in backbone. PPp-W could significantly prolong APTT (12.9 ± 0.42 s, p &lt; 0.001) and thrombin time (39.9 ± 0.28 s, p &lt; 0.01) compared with the control group (11.45 ± 0.071 s and 38.05 ± 0.21 s), which showed that PPp-W had anticoagulant activity. These studies suggested that PPp-W was a 3-O-methylated heteroglycan and might be suitable for functional foods and natural drugs as an anticoagulant ingredient, which provided a basis for the application of polysaccharides from P. placentodes.