bluuebunny/crossref_metadata_2025_split huggingface dataset:
Percutaneous Coronary Intervention with Everolimus-Eluting Versus Sirolimus-Eluting Stents in Diabetic Patients Presented with Acute Coronary Syndromes: A Short-term Comparative Clinical Outcome Study
Authors: Ibrahim Karim Mohamed Fahmy Mohamed , Sheikh Raghda Ghonimy El , Salama Mai Abdulmonaem , Ashmawy Medhat Mohamed , El-Sokkary Hatem Mohamed 
Published: September 2022

Background: The use of drug-eluting stents (DES) resulted in innovative progress in the field of interventional Cardiology. Nowadays, the most common indication for coronary stenting is acute coronary syndromes (ACS) due to the better clinical consequences of PCI compared with conservative management. However, in diabetic patients, there is a large debate in the literature regarding the selection of an optimal drug-eluting stent.
Aim: This work aimed to compare short term clinical outcome post-percutaneous Coronary intervention with Everolimus-eluting stents (EES) versus Sirolimus-eluting stents (SES) in diabetic patients presented with ACS.
Methods: The present study was carried out on 120 diabetic patients presented with acute coronary syndromes (Non-STEMI, Unstable angina) and divided into 2 groups; group 1 included patients treated with PCI with Everolimus eluting stenting (EES), and group 2 included patients treated with PCI with Sirolimus-eluting stenting (SES).
Results: After 6 months of follow-up, the percentages of treated patients who were complicated with sudden cardiac death, congestive heart failure, and planned further PCI were 5%, 6.7%, and 6.7%, respectively in group 1, and were 3.3%, 8.3%, and 10% respectively in group 2. While no acute coronary syndrome or repeated coronary angiography was reported in both groups. In the current study, there was no statistically significant difference between the EES group and the SES group in diabetic patients either during implantation or during 6 months follow up (P-value >0.05).
Conclusion: In this current study, both EES and SES are comparable to each other regarding the treatment of ACS in diabetic patients.
Isolation and Genetic Characterization of Gram-negative Bacteria from Different Fresh Retail Vegetables in Nigeria
Authors: Jesumirhewe C. , Dauda A. A. , Akhimien S. I. , Ruppitsch W. 
Published: September 2022

Aim: The proportion of food borne disease outbreaks as a result of contaminated products has increased over the years. In this study, the genetic characteristics of antibiotic resistant Gram-negative bacteria from different fresh retail vegetables in Okada, Edo state Nigeria was investigated.
Place and Duration of Study: In April-May 2021, the study was carried out in the Department of Pharmaceutical Microbiology, Igbinedion University Okada Edo state Nigeria.
Methodology: One hundred and eight isolates were isolated from sixteen different retail leafy and salad vegetable samples. Recovered isolates from samples were identified using standard microbiological techniques. Species identification for ten randomly selected isolates was performed by Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry and ribosomal multilocus sequence typing (rMLST). Antimicrobial susceptibility testing was performed using the Kirby-Bauer method for 15 antibiotics. Isolates were characterized by whole genome sequencing (WGS).
Results: Species identification using MALDI-TOF-MS and ribosomal MLST assigned the 10 randomly selected isolates to four different species. Identified isolates include Proteus mirabilis, Proteus vulgaris, Acinetobacter baumanii and Klebsiella quasipneumoniae. Out of the 10 randomly selected isolates, 60% (6/10) were antibiotic resistant in the antibiotic susceptibility test. WGS data confirmed the identities of the isolates except Proteus vulgaris identified as P. terrae. More than one resistant determinant was detected on the draft genome sequence of 80% (8/10) of the randomly selected isolates especially the regulatory system modulating antibiotic efflux CRP and the plasmid mediated quinolone resistant determinant qnrD1. Significantly, one Proteus mirabilis isolate was sensitive to the antibiotics in the phenotypic testing but had resistance determinants present.
Conclusion: This study provides genomic characterization of antibiotic resistant isolates from retail leafy and salad vegetables from Nigeria. Further study is important to understand the public health importance of such resistance and the amount of risk posed to human health by these resistant organisms.
Piscicoccus
Authors: Hamada Moriyuki 
Published: September 2022

Abstract

Pis.ci.coc'cus. L. masc. n.
piscis
, a fish; N.L. masc. n.
coccus
(from Gr. masc. n.
kokkos
grain, seed), coccus; N.L. masc. n.
Piscicoccus
, a coccus from a fish.

Actinobacteria / Actinomycetia / Dermatophilales / Dermatophilaceae / Piscicoccus

The genus
Piscicoccus
is Gram‐stain‐positive, facultatively anaerobic, and mesophilic actinobacterium. Cells are coccus‐shaped, nonmotile, and non‐endospore‐forming, and develop clusters of cuboid cells or coccoids. Catalase‐positive and oxidase‐negative. The cell‐wall peptidoglycan is of the A1γ type. The predominant isoprenoid quinone is MK‐8(H
4
) and the principal polar lipids are phosphatidylglycerol, phosphatidylinositol, and lyso‐phosphatidylethanolamine. The major cellular fatty acids consist of mono‐unsaturated and iso‐branched saturated fatty acids with C
17:1
, iso‐C
16:0
, and iso‐C
14:0
as the major components. The G + C content of the DNA is 71.8 mol%. Phylogenetically, the genus belongs to the family
Dermatophilaceae
within the order
Dermatophilales
. Currently, the genus contains only one validly published species: namely,
Piscicoccus intestinalis
. The type strain of
P. intestinalis
is Ngc37‐23
T
, which was isolated from the intestinal tract of a fish collected from beach on the coast of Tokyo Bay, Japan.

DNA G + C content (mol%)
: 71.8 (genome).

Type species
:
Piscicoccus intestinalis
Hamada et al. 2010, VL139.
Association of Area‐Level Heat and Social Vulnerability With Recurrent Hospitalizations Among Individuals With Rheumatic Conditions
Authors: Santacroce Leah , Dellaripa Paul F. , Costenbader Karen H. , Collins Jamie , Feldman Candace H. 
Published: September 2022

ObjectiveClimate and social vulnerability contribute to morbidity and health care utilization. We examined associations between the neighborhood Social Vulnerability Index (SVI) and the Heat Vulnerability Index (HVI) and recurrent hospitalizations among individuals with rheumatic conditions.MethodsUsing a Massachusetts multihospital centralized clinical data repository, we identified individuals ≥18 years of age with a rheumatic condition who received rheumatology care within 3 years of April 2021. We defined the index date as 2 years before the last encounter and the baseline period as 1 year pre‐index date. Addresses were geocoded and linked by census tract to the SVI and the HVI. We used multilevel, multinomial logistic regression to examine the odds of 1–3 and ≥4 hospitalizations (reference = 0) over 2 years post index date by vulnerability index, adjusting for age, gender, race/ethnicity, insurance, and comorbidities.ResultsAmong 14,401 individuals with rheumatic conditions, the mean ± age was 61.9 ± 15.7 years, 70% were female, 79% White, 7% Black, and 2% Hispanic. There were 8,251 hospitalizations; 11,649 individuals (81%) had 0 hospitalizations, 2,063 (14%) had 1–3, and 689 (5%) had ≥4. Adjusting for individual‐level factors, individuals living in the highest versus lowest SVI areas had 1.84 times higher odds (95% confidence interval [95% CI] 1.43–2.36) of ≥4 hospitalizations. Individuals living in the highest versus lowest HVI areas had 1.64 times greater odds (95% CI 1.17–2.31) of ≥4 hospitalizations.ConclusionIndividuals with rheumatic conditions living in areas with high versus low social and heat vulnerability had significantly greater odds of recurrent hospitalizations. Studies are needed to determine modifiable factors to mitigate risks.
Association of Systemic Sclerosis With Incident Clinically Evident Heart Failure
Authors: Lin Chun‐Yu , Chen Hung‐An , Chang Tsang‐Wei , Hsu Tsai‐Ching , Su Yu‐Jih 
Published: September 2022

ObjectivePrimary myocardial involvement is an important cause of death in systemic sclerosis (SSc). Subclinical diastolic/systolic heart dysfunction is recognized; however, whether this indicates a subsequent increased risk of clinically overt heart failure (HF) remains largely unknown. We aimed to investigate the risk of clinically overt HF in a large, unselected SSc cohort.MethodsThis matched, retrospective cohort study was conducted using a nationwide insurance database in Taiwan. Incident SSc patients with no history of HF were identified, and non‐SSc comparison groups were selected and matched to the SSc groups by age, sex, and cohort entry time. The cumulative HF incidence was estimated using the Kaplan‐Meier method. Multivariable Cox proportional hazards regression was used to calculate adjusted hazard ratios (HRs) for HF hospitalization.ResultsA total of 1,830 SSc patients and 27,981 controls were identified. The cumulative incidence of hospitalized HF at 3, 5, and 10 years among patients with SSc were 3.5%, 5.3%, and 9.7%, respectively. Compared with non‐SSc individuals, SSc patients had an increased risk of HF (adjusted HR 3.26 [95% confidence interval (95% CI) 2.49–4.28]). Subgroup analyses revealed that the impact of SSc on the occurrence of HF was greater among patients ages <50 years than those ages ≥50 years (HR 7.8 [95% CI 4.03–15.1] versus HR 2.78 [95% CI 2.06–3.76]).ConclusionSSc is associated with a markedly higher risk of clinically evident HF and not asymptomatic ventricular dysfunction alone. These findings provide real‐world evidence suggesting the use of appropriate screening strategies to detect these lethal complications early in SSc.
Tunable Electronic Properties of Novel 2D Janus MSiGeN4 (M = Ti, Zr, Hf) Monolayers by Strain and External Electric Field
Authors: Vi Vo T.T. , Linh Tran P.T. , Nguyen Cuong Q. , Hieu Nguyen N. 
Published: September 2022

AbstractSince the recent successful experimental synthesis of MoSi2N4 [Science, 369 (2020), 670], the “MA2Z4 family” has been of particular interest to the scientists in the field of materials science due to its outstanding physical properties. In this paper, the first‐principles calculations are performed to study the structural, elastic, and electronic properties of novel two‐dimensional (2D) Janus MSiGeN4 monolayers (M = Ti, Zr, Hf). The calculations of phonon spectra indicate that monolayers MSiGeN4 are dynamically stable and can be experimentally synthesized. The obtained Young's modulus and Poisson's ratio of the Janus structures MSiGeN4 are much larger than that of other binary 2D materials and meet the mechanical stability criteria suggested by Born and Huang. In the calculations using either PBE or HSE06 functionals, the Janus MSiGeN4 structures exhibit indirect semiconductor characteristics with larger band gaps than that of similar septuple‐atomic‐layer materials, such as MoSiGeN4 and WSiGeN4. In addition, the influences of biaxial strain and external electric field on the electronic structure of MSiGeN4 are investigated. It is found that the biaxial strain tunes the electronic characteristics more significantly than the external electric field. The obtained results can provide insights into novel Janus monolayers with potential applications in electronic devices.
Understanding the Structural Elasticity of RNA and DNA: All‐Atom Molecular Dynamics
Authors: Zhang Yingtong , Yan Miao , Huang Tingting , Wang Xianghong 
Published: September 2022

AbstractNucleic acids play essential roles in some biological processes and nanotechnology. Understanding their structural elasticity is very important for biological functions. Differences in structural elasticity of RNA and DNA duplexes are investigated by all‐atom molecular dynamics in this work. Two models double‐strand (ds) B‐DNA and A‐RNA short sequences are used. For two typical sequences, bending persistence length, stretch, and twist modulus are analyzed and compared in detail. These results demonstrate that dsDNA has a smaller bending persistence length value than dsRNA, however, the former has about 2.6 times stretch modulus than the latter one and the twist modulus in the former is smaller than the latter. Furthermore, the microstructural parameter analysis indicates that the inclination angle of a single base pair and the dihedral angle between two bases in a base pair, as well as the slide between adjacent base pairs, influences the structural elasticities of these two types of nucleic acids. Results also show that the dsDNA has a positive stretch‐twist coupling parameter while the dsRNA has a negative stretch‐twist coupling parameter. Results offer research comprehensive comparing and understanding about structural elasticity of RNA and DNA and provide novel perspectives for grasping nucleic acids' elastic properties.
Carrier Multiplication in Transition Metal Dichalcogenides Beyond Threshold Limit
Authors: Liu Yuxiang , Frauenheim Thomas , Yam ChiYung 
Published: September 2022

AbstractCarrier multiplication (CM), multiexciton generation by absorbing a single photon, enables disruptive improvements in photovoltaic conversion efficiency. However, energy conservation constrains the threshold energy to at least twice bandgap (2). Here, a below threshold limit CM in monolayer transition metal dichalcogenides (TMDCs) is reported. Surprisingly, CM is observed with excitation energy of only 1.75 due to lattice vibrations. Electron–phonon coupling (EPC) results in significant changes in electronic structures, which favors CM. Indeed, the strongest EPC in monolayer MoS2 leads to the most efficient CM among the studied TMDCs. For practical applications, chalcogen vacancies can further lower the threshold by introducing defect states within bandgap. In particular, for monolayer WS2, CM occurs with excitation energy as low as 1.51 . The results identify TMDCs as attractive candidate materials for efficient optoelectronic devices with the advantages of high photoconductivity and efficient CM.
Constructing an Overall Static Negative Capacitance Effect via Energy Landscape Designing
Authors: Qiao Leilei , Song Cheng , Wang Qian , Zhou Yongjian , Pan Feng 
Published: September 2022

AbstractThe negative capacitance (NC) effect in ferroelectrics and antiferroelectrics is promising to reduce power dissipation and enable energy storage applications. However, the limited electric field scale and hysteresis properties of NC effect in ferroelectrics and antiferroelectrics seriously limit its application in transistors and energy‐storage supercapacitors. Here, an overall (non‐local) static (hysteresis‐free) NC effect is developed via energy landscape designing. The ferroelectric structure is introduced into the traditional antiferroelectric PbZrO3 film, thus the single‐well energy landscape is tuned to an upper convex function. This anomalous energy landscape generates a hysteresis‐free and single‐valued polarization‐electric field behavior (P–E) curve with a negative slope (dP/dE < 0), which guarantees the NC effect is static and available over the entire electric field range. Such an NC effect in PbZrO3 film is stabilized by connecting a dielectric Al2O3 layer in series. This finding advances the practical application of the NC effect, especially in transistors and supercapacitors.
Building Efficient and Durable Hetero‐Interfaces on a Perovskite‐Based Electrode for Electrochemical CO2 Reduction
Authors: He Fan , Hou Mingyang , Zhu Feng , Liu Dongliang , Zhang Hua , Yu Feifei , Zhou Yucun , Ding Yong , Liu Meilin , Chen Yu 
Published: September 2022

AbstractSolid oxide electrochemical cells (SOECs) have demonstrated the potential to be highly efficient devices for electrochemical CO2 reduction (CO2R) at intermediate temperatures. However, the performance and widespread applications for CO2R largely hinge on the sluggish reaction kinetics and poor durability of the state‐of‐the‐art electrodes. Here, the findings in enhancing the reaction activity and durability of a perovskite‐based electrode are reported, Sr2Fe1.5Mo0.3Cu0.2O6‐δ (SF1.5MC), for electrochemical oxidation of H2 and reduction of CO2. Under typical operating conditions, the SF1.5MC electrode is elegantly reconstructed into three phases of oxygen vacancy‐rich double perovskite (DP), Ruddlesden‐popper (RP), and Cu‐Fe metals, as confirmed by X‐ray diffraction and scanning transmission electron microscopy. When applied as a fuel electrode for an electrolyte‐supported SOEC, decent performances are demonstrated at 800 °C, showing a maximum power density of 1.51 W cm−2 in fuel cell mode (on H2 fuel) and a current density of 1.94 A cm−2 at 1.4 V in electrochemical CO2R to CO with high Faradaic efficiencies of ≈100% and good durability.
Self‐Frequency‐Mixing Raman Laser Based on RbTiOPO4
Authors: Zhu Haiyong , Liu Jie , Qi Ziqin , Lu Huanqia , Cheng Yuxuan , Wang Hongyan , Zhang Ge , Duan Yanmin 
Published: September 2022

AbstractIn this work, the generation of yellow laser emission from a self‐frequency‐mixing Raman laser utilizing RbTiOPO4 (RTP) is reported. The RTP crystal is positioned within the cavity of a Nd:YAG/Cr4+:YAG composite, passively Q‐switched laser. By utilizing this intracavity configuration, Raman conversion of the fundamental laser wavelength to Stokes wavelengths and frequency mixing of these near‐infrared wavelengths to the visible wavelength range is achieved using a single RTP crystal. Multiple visible wavelengths are generated, with a primary line at 574.3 nm and additional weaker lines at 552.3 and 563.9 nm. An average output power of 180 mW is measured from the output coupler end of the laser setup (note that laser emission in the visible wavelength range is also generated toward the input end of the laser cavity) for an incident pump power of 11.4 W. The results demonstrate the potential of RTP as a self‐frequency‐mixing, Raman crystal, which may be used for the development of efficient and compact yellow lasers.
Comparing pellet‐ and filament‐based additive manufacturing with conventional processing for ABS and PLA parts
Authors: La Gala Andrea , Ceretti Daniel V. A. , Fiorio Rudinei , Cardon Ludwig , D'hooge Dagmar R. 
Published: September 2022

AbstractMore recently pellet‐based additive manufacturing or so‐called micro‐extrusion has become more popular for final polymeric part production. In the present work, it is evaluated how pellet‐based AM (PBAM) performs for its extrudates and specimens compared to the more established fused filament fabrication technique, considering both commercial acrylonitrile butadiene styrene polymer and poly(lactic acid) pellets and filaments as feedstocks. For benchmarking purposes, a comparison with conventional techniques, that is, single screw extrusion and injection molding, is also included. To support the performance interpretation a theoretical analysis is conducted regarding the melting finalization point as well as void measurements and Fourier transfer infrared spectroscopic analysis for degradation effects are included. It is demonstrated that for the extrudates comparable results are obtained among the different manufacturing techniques, whereas for the specimens the situation is dissimilar. It is highlighted that PBAM/ME has a large market potential implementation, provided that its operating settings are further optimized.
Optimization of culture conditions for enhanced production of extracellular α‐amylase using solid‐state and submerged fermentation from Aspergillus tamarii MTCC5152
Authors: Premalatha Arunachallam , Vijayalakshmi Kumaravel , Shanmugavel Muthiah , Rajakumar Gopal Suseela 
Published: September 2022

AbstractAmylases are one of the main enzymes used in various industries such as food, fermentation, textile, and pharmaceuticals. Microorganisms are the potent sources of amylase enzyme, apart from plant and animal sources. Fungal amylases are more stable than bacterial amylases. The production of extracellular α‐amylase from Aspergillus tamarii MTCC5152 using solid‐state and submerged fermentation (SSF and SmF) and the various nutritional factors influencing its production were studied. A higher activity of α‐amylase (519.40 u/g) was attained in a medium having wheat bran (WB) alone as the substrate at an initial moisture content of 70% (v/w) with 2.5% (v/w) of inoculum level (containing 106 spores/ml) after 4 days of incubation at 28°C by SSF. Addition of 1% glucose to WB containing basal medium enhanced α‐amylase production (6.49 u/ml) after 4 days of incubation by SmF method. Comparative evaluation of enzyme production by SSF and SmF methods produced better results in SSF method.
Statistical review of animal trials—A guideline
Authors: Piper Sophie K. , Zocholl Dario , Toelch Ulf , Roehle Robert , Stroux Andrea , Hoessler Johanna , Zinke Anne , Konietschke Frank 
Published: September 2022

AbstractAny experiment involving living organisms requires justification of the need and moral defensibleness of the study. Statistical planning, design, and sample size calculation of the experiment are no less important review criteria than general medical and ethical points to consider. Errors made in the statistical planning and data evaluation phase can have severe consequences on both results and conclusions. They might proliferate and thus impact future trials—an unintended outcome of fundamental research with profound ethical consequences. Unified statistical standards are currently missing for animal review boards in Germany. In order to accompany, we developed a biometric form to be filled and handed in with the proposal at the concerned local authority on animal welfare. It addresses relevant points to consider for biostatistical planning of animal experiments and can help both the applicants and the reviewers in overseeing the entire experiment(s) planned. Furthermore, the form might also aid in meeting the current standards set by the 3+3R's principle of animal experimentation: Replacement, Reduction, Refinement as well as Robustness, Registration, and Reporting. The form has already been in use by the concerned local authority of animal welfare in Berlin, Germany. In addition, we provide reference to our user guide giving more detailed explanation and examples for each section of the biometric form. Unifying the set of biostatistical aspects will help both the applicants and the reviewers to equal standards and increase quality of preclinical research projects, also for translational, multicenter, or international studies.