bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Double‐Circle System in the Greater Tuberosity: Using Radius to Predict Rotator Cuff Tear
Authors: Ma Qi , Sun Changjiao , Liu Pu , Yu Peng , Cai Xu 
Published: April 2022

ObjectiveIn this study we concerned on the morphological characteristics of the greater tuberosity of humerus and proposed the double‐circle radius ratio as a new predictor for the diagnosis of rotator cuff tears.MethodsThis was a retrospective study and patients who visited our hospital and were diagnosed with or without rotator cuff tears via magnetic resonance imaging from January 2018 to July 2021 were enrolled and classified into two groups respectively. In a standard anteroposterior view, the radius of the best‐fit circle of humeral head and the radius of the concentric circle passing through the most lateral edge of the greater tuberosity were measured in each shoulder. The ratio of these two radiuses was named as the double‐circle radius ratio. Angular parameters including the greater tuberosity angle and the critical shoulder angle were also measured in the anteroposterior view. Independent samples t tests and chi‐square tests were used to find significant differences between groups. Significant associations between those measured variables and demographic characteristics were analyzed with simple linear regression analysis. Receiver operating characteristic curves were pictured to determine applied cutoff values by using Youden index. Multivariable‐adjusted analysis for the occurrence of rotator cuff tears was carried out by using multiple logistic regression analysis. For all tests a p value of <0.05 was considered statistically significant.ResultsOne hundred and twelve shoulders with rotator cuff tears and 42 shoulders without rotator cuff tears were included. The mean value of the double‐circle radius ratio was significantly larger in shoulders with rotator cuff tears (1.42 ± 0.09 vs. 1.30 ± 0.07, P = 0.000). With simple linear regression analysis, the radiuses of the humeral head and the greater tuberosity were significantly associated with heights and weights. In receiver operating characteristic curves, the largest area was found under the curve of the double‐circle radius ratio as 0.846 (95% CI, 0.781–0.911; P = 0.000) with an applied cutoff value as 1.38 (sensitivity, 70.5%; specificity, 88.1%). Multivariable‐adjusted analysis showed that a value of the double‐circle radius ratio >1.38 resulted in 11.252‐fold odds of developing rotator cuff tears (95% CI, 3.388–37.368; P = 0.000).ConclusionThe double‐circle radius ratio is significantly larger in patients with rotator cuff tears and could be regarded as an eligible predictor for rotator cuff tears.
Early priming of asthma and respiratory allergies: Future aspects of prevention
Authors: Wahn Ulrich , Lau Susanne , Eigenmann Philippe , Melen Erik , Krauss‐Etschmann Susanne , Lex Christiane , Matricardi Paolo , Schaub Bianca , Halken Susanne , Ege Markus , Jackson Daniel , Hamelmann Eckard , Szépfalusi Zsolt , Garcia Antonio N. , von Mutius Erika 
Published: April 2022

AbstractIn order to summarize recent research on the prevention of allergies—particularly asthma—and stimulate new activities for future initiatives, a virtual workshop sponsored by the EAACI Clemens von Pirquet foundation and EUFOREA was held in October 2021. The determinants of the “allergic march” as well as the key messages from intervention studies were reviewed by an international faculty of experts. Several unmet needs were identified, and a number of priorities for future studies were proposed.
The service user experience of SlowMo therapy: A co‐produced thematic analysis of service users’ subjective experience
Authors: Greenwood Kathryn E. , Gurnani Megha , Ward Tom , Vogel Evelin , Vella Claire , McGourty Alison , Robertson Sam , Sacadura Catarina , Hardy Amy , Rus‐Calafell Mar , Collett Nicola , Emsley Richard , Freeman Daniel , Fowler David , Kuipers Elizabeth , Bebbington Paul , Dunn Graham , Michelson Daniel , Garety Philippa ,   the SlowMo Patient, Public Involvement (PPI) team
Published: April 2022

AbstractObjectivesSlowMo is the first blended digital therapy for paranoia, showing significant small‐moderate reductions in paranoia in a recent large‐scale randomized controlled trial (RCT). This study explored the subjective service‐user experience of the SlowMo therapy content and design; the experience of the blended therapy approach, including the triangle of the therapeutic alliance; and the experience of the digital aspects of the intervention.DesignQualitative co‐produced sub‐study of an RCT.MethodsParticipants were 22 adult service users with schizophrenia‐spectrum psychosis and persistent distressing paranoia, who completed at least one SlowMo therapy session and a 24‐week follow‐up, at one of 3 sites in Oxford, London, and Sussex, UK. They were interviewed by peer researchers, using a topic guide co‐produced by the Patient and Public Involvement (PPI) team. The transcribed data were analysed thematically. Multiple coding and triangulation, and lay peer researcher validation were used to reach a consensus on the final theme structure.ResultsSix core themes were identified: (i) starting the SlowMo journey; (ii) the central role of the supportive therapist; (iii) slowing things down; (iv) value and learning from social connections; (v) approaches and challenges of technology; and (vi) improvements in paranoia and well‐being.ConclusionsFor these service users, slowing down for a moment was helpful, and integrated into thinking over time. Learning from social connections reflected reduced isolation, and enhanced learning through videos, vignettes, and peers. The central role of the supportive therapist and the triangle of alliance between service user, therapist, and digital platform were effective in promoting positive therapeutic outcomes.
Distinctively political normativity in political theory
Authors: Erman Eva , Möller Niklas 
Published: April 2022

AbstractRecent years' literature on distinctively political normativity raises methodological and meta‐theoretical concerns of importance for political theory. The aim of this article is to identify and critically examine the main positions in this debate as well as to analyze problems and promising ways forward. In brief, we argue that the predominant “non‐moral view” of distinctively political normativity (i.e., the view that political normativity is independent of moral normativity), is problematic in all its three versions. Further, we suggest that a reasonable approach to political normativity should adopt a “moral view” (i.e., the view that political normativity is not independent of moral normativity) and investigate two such approaches: the so‐called “filter approach” and the “role approach.” Although still much in need of further development in political theory, both of them bear promise as accounts which preserve the distinctness of the political domain while acknowledging its status as a moral kind.
Epidemiology of interstitial lung disease in systemic lupus erythematosus in France: A nation‐wide population‐based study over 10 years
Authors: Mageau Arthur , Borie Raphaël , Crestani Bruno , Timsit Jean‐François , Papo Thomas , Sacre Karim 
Published: April 2022

AbstractBackground and objectiveData regarding interstitial lung disease (ILD) in the setting of systemic lupus erythematosus (SLE) are limited. We used a nationwide database to determine the incidence and the prevalence of ILD in SLE.MethodsCharacteristics of all SLE inpatients admitted between 2011 and 2012 in France were analysed through the French medico‐administrative database. Features associated with the presence of ILD were studied. Cox hazard model was used to measure the impact of ILD on survival from the first stay to 2020. The incidence of ILD in SLE was estimated by analysing the onset of ILD from 2013 to 2020 in SLE patients who had no evidence of ILD in 2013.ResultsBetween 2011 and 2012, 10,460 SLE patients had at least one hospital stay and could be traced until 2020. Among them, 134 (1.2%) had an ILD diagnosed at baseline. The frequency of ILD in SLE was higher in patients who had an associated autoimmune disease such as Sjögren's syndrome or systemic sclerosis (29.9% vs. 5.9%, p < 0.0001). ILD was associated with an increased risk of death in SLE in the multivariable analysis (hazard ratio [95% CI] 1.992 [1.420–2.794]; p < 0.0001). Among the 31,029 SLE patients with no evidence of ILD at baseline, ILD occurred in 795 (2.6%) between 2013 and 2020. The incidence rate of ILD in SLE was 10.26 for 1000 patient‐years [95% CI: 10.24–10.28].ConclusionIn SLE, ILD is exceedingly rare, often associated with another systemic autoimmune disorder and appears as a major risk factor for death.
Adjusting Misclassification using a Second Classifier with an External Validation Sample
Authors: Schenkel Jonas F. , Zhang Li-Chun 
Published: April 2022

AbstractAdministrative data may suffer from delays or mistakes in reporting. To adjust for the resulting measurement errors, it is often necessary to combine data from related sources, such as sample survey, administrative or ‘big’ data. However, the additional measure variable usually has a different definition and errors of its own, and the available joint data set may not have a completely known sampling distribution. We develop a modelling approach which capitalizes on one's knowledge and experience with the data source where they exist, and apply it to register- and survey-based Employed status. Comparisons are made to adjustments by hidden Markov models. Our approach is applicable to similar situations involving big data sources.
Abnormally low heat flow in Southeast China resulted from remnant slab subducted beneath the east Asian lithosphere
Authors: Gan Haonan , Wang Guiling , Wang Bo , Wang Xiao , Lin Wenjing , Yue Gaofan , Tan Xianfeng 
Published: April 2022

AbstractSubducted remnant slabs play an important role in the geodynamics and evolution of the Earth, but their behaviour in the mantle is not well understood. Terrestrial heat flow and thermal lithosphere structure provide crucial constraints on lithospheric dynamics. Based on whole‐well steady‐state temperature logs and conductivity measurements of core samples from a scientific borehole, we obtained a new high‐quality terrestrial heat flow values for East Asia. The heat flow was calculated at 60.6 ± 16.0 mW/m2with a high crust/mantle heat flow ratio of 1.41, suggesting a hot‐crust‐cold‐mantle lithospheric structure. The thermal lithospheric thickness of eastern Fujian is estimated to be 152–166 km, indicating a thick and cold lithosphere. We demonstrate that the cooling of the lithosphere is caused by a remnant palaeo‐slab of the Palaeo‐Pacific plate subducted beneath SE China. The remnant slab blocked heat convection into the bottom of the lithosphere of the Eurasian Plate.
Antioxidants in single methylene‐blue‐treated plasma units cannot be used to predict pathogen inactivation treatment success
Authors: Lotens Anaïs , Prudent Michel , Rapaille André 
Published: April 2022

AbstractBackground and ObjectivesMeasurement of antioxidant power (AOP) can be useful to validate the execution of the pathogen inactivation (PI) treatment of plasma units. The aim of this study was to evaluate the Theraflex technology for plasma units routinely used in Belgium.Materials and MethodsAOP was tested on plasma units treated by Theraflex with various non‐complete treatment scenarios. AOP was quantified electrochemically using disposable devices and was expressed as equivalent ascorbic acid concentration.ResultsDuring a complete PI treatment, AOP rose from 195 ± 32 to 230 ± 42 μmol/L eq. ascorbic acid after addition of methylene blue (MB), and decreased to 192 ± 30 μmol/L eq. ascorbic acid after illumination and finally to 177 ± 27 μmol/L eq. ascorbic acid after final filtration. Without MB, the final filtration had no effect on the plasma AOP (197 ± 22 μmol/L eq. ascorbic acid before filtration and 194 ± 22 μmol/L eq. ascorbic acid after filtration). With no MB and no illumination, there was no significant difference between the plasma AOP at the beginning (188 ± 23 μmol/L eq. ascorbic acid) and at the end of the process (179 ± 21 μmol/L eq. ascorbic acid).ConclusionAOP measurement may not indicate the effectiveness of the PI treatment.
Evidence of influenza A infection and risk of transmission between pigs and farmworkers
Authors: Lopez‐Moreno Gustavo , Davies Peter , Yang My , Culhane Marie R. , Corzo Cesar A. , Li Chong , Rendahl Aaron , Torremorell Montserrat 
Published: April 2022

AbstractInterspecies transmission of influenza A virus (IAV) between pigs and people represents a threat to both animal and public health. To better understand the risks of influenza transmission at the human–animal interface, we evaluated 1) the rate of IAV detection in swine farmworkers before and after work during two human influenza seasons, 2) assessed risk factors associated with IAV detection in farmworkers and 3) characterized the genetic sequences of IAV detected in both workers and pigs. Of 58 workers providing nasal passage samples during 8‐week periods during the 2017/18 and 2018/19 influenza seasons, 33 (57%) tested positive by rRT‐PCR at least once. Sixteen (27%) workers tested positive before work and 24 (41%) after work. At the sample level, 58 of 1,785 nasal swabs (3.2%) tested rRT‐PCR positive, of which 20 of 898 (2.2%) were collected prior to work and 38 of 887 (4.3%) after work. Although farmworkers were more likely to test positive at the end of the working day (OR = 1.98, 95% CI 1.14–3.41), there were no influenza‐like illness (ILI) symptoms, or other risk indicators, associated with IAV detection before or after reporting to work. Direct whole‐genome sequencing from samples obtained from worker nasal passages indicated evidence of infection of a worker with pandemic 2009 H1N1 of human‐origin IAV (H1‐pdm 1A 3.3.2) when reporting to work, and exposure of several workers to a swine‐origin IAV (H1‐alpha 1A 1.1) circulating in the pigs on the farm where they were employed. Our study provides evidence of 1) risk of IAV transmission between pigs and people, 2) pandemic H1N1 IAV infected workers reporting to work and 3) workers exposed to swine harbouring swine‐origin IAV in their nasal passages temporarily. Overall, our results emphasize the need to implement surveillance and transmission preventive protocols at the pig/human interface.
Fire and Explosion Risks and Consequences in Electrical Substations—A Transformer Case Study
Authors: El-Harbawi Mohanad 
Published: April 2022

Abstract
This study aims to find how fires and explosions can occur in enclosed spaces where electrical transformers are installed and to investigate the consequences of the damages to the surrounding areas caused by these accidents. This study began with the collection of a mineral oil waste sample from an indoor substation transformer in Riyadh, Saudi Arabia. This sample was analyzed to determine its composition. Results revealed that 30 components ranging from C6 to C30 were detected in the sample. The mixture flammability limits, calculated using Le Chatelier rules and found to be 0.97 and 6.56, indicated that the vapor mixture for the waste oil sample was not flammable at 25 °C and 1 atm. Consequence analysis was used to predict the outcome of fire and explosion events based on a transformer with a capacity of 1100 liters. The peak overpressure generated by an explosion was estimated to be 80.97 kPa. Moreover, the thermal radiation produced by various types of fires was estimated as a function of the distance from the accident center. The thermal flux from a boiling liquid expanding vapor explosion (BLEVE) was 99.8 kW/m2, which is greater than that from jet and pool fires. The probability of an individual suffering injury or dying as a result of exposure to fire and/or an explosion was estimated using dose-response models. The results showed that the peak overpressure produced by an explosion can cause severe damage within 20 m of the explosion center. However, the results also showed that there is a 100% probability of the thermal radiation from a BLEVE causing fatalities up to a distance of 140 m. The risk due to the fragmentation of the transformer tanks was also assessed, and a majority of fragments would land within a range of 111.2 m.
A Review of Head Injury Metrics Used in Automotive Safety and Sports Protective Equipment
Authors: Rowson Bethany , Duma Stefan M. 
Published: April 2022

Abstract
Despite advances in the understanding of human tolerances to brain injury, injury metrics used in automotive safety and protective equipment standards have changed little since they were first implemented nearly a half-century ago. Although numerous metrics have been proposed as improvements over the ones currently used, evaluating the predictive capability of these metrics is challenging. The purpose of this review is to summarize existing head injury metrics that have been proposed for both severe head injuries, such as skull fractures and traumatic brain injuries (TBI), and mild traumatic brain injuries (mTBI) including concussions. Metrics have been developed based on head kinematics or intracranial parameters such as brain tissue stress and strain. Kinematic metrics are either based on translational motion, rotational motion, or a combination of the two. Tissue-based metrics are based on finite element model simulations or in vitro experiments. This review concludes with a discussion of the limitations of current metrics and how improvements can be made in the future.
Role of CuO in Al2O3-B2O3 Composites: In Situ Phases, Density, Hardness, and Wear Resistance
Authors: Kasar Ashish K. , D’Souza Brian , Watson Kevin P. , Menezes Pradeep L. 
Published: April 2022

Abstract
The aim of this study was to develop a novel set of Al2O3-B2O3-CuO composites and evaluate their tribological performance at varying humidity (10–95% relative humidity) levels. First, the Al2O3-B2O3 composites were prepared using cold press sintering by varying the amount of B2O3 (5–20 wt%). The results revealed that an increase in B2O3 content in the composites increased the amount of aluminum borate in situ phase during sintering. The presence of the aluminum borate phase in the composite enhanced the hardness and wear resistance, whereas the humidity-sensitive alumina phase reduced friction at higher humidity levels. Next, CuO (5 wt%) was added to the Al2O3-B2O3 composites to form Al2O3-B2O3-CuO composites. These composites showed an increase in the percentage relative density by 16–37% and hardness by 1.2–1.9 times. Subsequently, the tribological performance was improved significantly. The underlying mechanism for improved wear resistance was discussed using the crystal-chemical approach and polarization theory to guide the design of these novel Al2O3-B2O3-CuO composites.
Supplemental Material: Permeability of subducted oceanic crust revealed by eclogite-facies vugs
Authors: Angiboust Samuel , Raimondo Tom 
Published: April 2022

<p>Analytical methods, details on the pseudosection modeling, and permeability calculation approaches; and a regional geological map, chemical mineral data, as well as the complete set of LA-ICP-MS maps. </p>
Epidemiology of adverse drug events and medication errors in four nursing homes in Japan: the Japan Adverse Drug Events (JADE) Study
Authors: Ayani Nobutaka , Oya Nozomu , Kitaoka Riki , Kuwahara Akiko , Morimoto Takeshi , Sakuma Mio , Narumoto Jin 
Published: April 2022

BackgroundWorldwide, the emergence of super-ageing societies has increased the number of older people requiring support for daily activities. Many elderly residents of nursing homes (NHs) take drugs to treat chronic conditions; however, there are few reports of medication safety in NHs, especially from non-western countries.ObjectiveWe examined the incidence and nature of adverse drug events (ADEs) and medication errors (MEs) in NHs for the elderly in Japan.Design, setting, and participantsThe Japan Adverse Drug Events Study for NHs is a prospective cohort study that was conducted among all residents, except for short-term admissions, at four NHs for older people in Japan for 1 year.MeasurementsTrained physicians and psychologists, five and six in number, respectively, reviewed all charts of the residents to identify suspected ADEs and MEs, which were then classified by the physicians into ADEs, potential ADEs and other MEs after the exclusion of ineligible events, for the assessment of their severity and preventability. The kappa score for presence of an ADE and preventability were 0.89 and 0.79, respectively.ResultsWe enrolled 459 residents, and this yielded 3315 resident-months of observation time. We identified 1207 ADEs and 600 MEs (incidence: 36.4 and 18.1 per 100 resident-months, respectively) during the study period. About one-third of ADEs were preventable, and MEs were most frequently observed in the monitoring stage (72%, 433/600), with 71% of the MEs occurring due to inadequate observation following the physician’s prescription.ConclusionIn Japan, ADEs and MEs are common among elderly residents of NHs. The assessment and appropriate adjustment of medication preadmission and postadmission to NHs are needed to improve medication safety, especially when a single physician is responsible for prescribing most medications for the residents, as is usually the case in Japan.
Five-dimensional Yang–Mills black holes in massive gravity’s rainbow
Authors: Aounallah Houcine , Pourhassan Behnam , Hendi Seyed Hossein , Faizal Mir 
Published: April 2022

AbstractIn this paper, we will analyze a five-dimensional Yang–Mills black hole solution in massive gravity’s rainbow. We will also investigate the flow of such a solution with scale. Then, we will discuss the scale dependence of the thermodynamics for this black hole. In addition, we study the criticality in the extended phase space by treating the cosmological constant as the thermodynamics pressure of this black hole solution. Moreover, we will use the partition function for this solution to obtain corrections to the thermodynamics of this system and examine their key role in the behavior of corrected solutions.
LIV effects on the quantum stochastic motion in an acoustic FRW-geometry
Authors: Anacleto M. A. , Bessa C. H. G. , Brito F. A. , Mateus A. E. , Passos E. , Santos J. R. L. 
Published: April 2022

AbstractIt is well known in the literature that vacuum fluctuations can induce a random motion of particles which is sometimes called quantum Brownian motion or quantum stochastic motion. In this paper, we consider Lorentz Invariance Violation (LIV) in an acoustic spatially flat Friedman–Robertson–Walker (FRW) geometry. In particular, we are looking for the LIV effects in the stochastic motion of scalar and massive test particles. This motion is induced by a massless quantized scalar field on this geometry, which in turn is derived from an Abelian Higgs model with LIV. Deviations in the velocity dispersion of the particles proportional to the LIV parameter are found.
The self-energy of Friedrichs–Lee models and its application to bound states and resonances
Authors: Lonigro Davide 
Published: April 2022

AbstractA system composed of two-level systems interacting with a single excitation of a one-dimensional boson field with continuous spectrum, described by a Friedrichs (or Friedrichs–Lee) model, can exhibit bound states and resonances; the latter can be characterized by computing the so-called self-energy of the model. We evaluate an analytic expression, valid for a large class of dispersion relations and coupling functions, for the self-energy of such models. Afterwards, we focus on the case of identical two-level systems, and we refine our analysis by distinguishing between dominant and suppressed contributions to the associated self-energy; we finally examine the phenomenology of bound states in the presence of a single dominant contribution.