bluuebunny/crossref_metadata_2025_split huggingface dataset:
Scan-to-BIM technique in building maintenance projects: practicing quantity take-off
Authors: Sing Michael C.P. , Luk Sophie, Y.Y. , Chan Ken H.C. , Liu Henry J. , Humphrey Richard 
Published: September 2022

PurposeIn Hong Kong, over 20,000 private residential buildings will be 50 plus years old by 2039. However, building maintenance has not been owners’ popular interest because of the high cost as well as the complexities in justifying whether the quantities and prices of the maintenance works are reasonable. This paper therefore aims to validate the practicality of adopting Scan-to-BIM: Terrestrial Laser Scan (TLS) and Building Information Modelling (BIM) to perform quantity take-offs (QTO) for estimating building maintenance costs.Design/methodology/approachA 64-year-old tenement building was selected to conduct a case study. In this instance, the building had undergone a Scan-to-BIM survey approach to generate QTO for the bills of quantities for external painting works. The Scan-to-BIM approach includes site visit, positioning of scanning equipment, assignment of circular scan routes, point cloud registration and identification of residual error. After that, time, cost and quality data were logged into contrast with QTO on as-built plans for external wall plastering works.FindingsThe “time”, “cost” and “quality” of the Scan-to BIM practice were then examined and compared with the prevailing practices of manual measurements on as-built drawings. As noted from the results, the initial cost of Scan-to BIM is high, owing to the cost of equipment, software and capable available operators. However, the authors identified that the time and cost can be significantly minimised by developing and implementing efficient practices such as preparing a detailed scan plan, equipping modeller with quantity surveying knowledge, using automated object recognition and 5D BIM software packages such as Vico Office and CostX.Practical implicationsThe upshot is that Scan-to-BIM could be one of the measures to advance the clarity in the QTO and estimated price of the maintenance projects.Originality/valueThe practicability of Scan-to-BIM has received limited attention on existing building maintenance project. The Scan-to-BIM approach was examined using a case building of a 64-year-old tenement building. The approach demonstrated in this research study is promised to advance the clarity in the QTO and estimated price of maintenance project.
Mindfulness–based positive transformative leadership development for health organisations
Authors: Paul David 
Published: September 2022

Purpose
Positive transformative leadership development practices in health care are perhaps the most important pathway that, collectively, can be pursued while heading towards a post-corona virus disease 2019 world, and race towards 2030. As a practitioner paper, based on front line and leadership experience, this study aims to argue that we need transformational leaders who will go beyond knowing to practice and implementation. While the findings from research is presented from different organisations and companies, they all have something in common – people. Hence, important lessons can be extrapolated to health-related organisations in the future.

Design/methodology/approach
The approach is based on practical research findings based on the literature. The approach uses real practical examples from companies and organisations to demonstrate the need for a new, radical way forward.

Findings
The findings from the literature clearly indicate that mindfulness-based transformative leadership development program is a worthwhile investment for decision-makers and organisations. A new transformative leader for the future of health care needs to be developed with care with investment in that development.

Research limitations/implications
Implications of this paper show that health-care organisations need to begin this journey. There is a paucity in the literature to demonstrate the implementation of mindfulness-based transformative leadership development programs.

Practical implications
Organisations of the future face even greater challenges brought about by intelligent technology, new pandemics and even tighter government regulation. The time to prepare for such eventualities is now. This is not a choice but an imperative for organisations to know what to do rather than react with regret.

Originality/value
There is a paucity in the health-care literature that tracks, measures, and reports on the long-term results of a mindfulness-based transformative leadership development program. This needs to be addressed, and health care should be a leader in the field of mindfulness and transformative leadership of the future.
Effects of 60Co γ ray radiation on the transmission characteristics of interconnection structures for 3D packaging
Authors: Zhang Youxin , Liu Yang , Cao Rongxing , Zeng Xianghua , Xue Yuxiong 
Published: September 2022

Purpose
Concerning the radiation effects on the three-dimensional (3D) packaging in space environment, this study aims to investigate the influence of the total dose effect on the transmission characteristics of high-frequency electrical signals using experimental and simulation methods.

Design/methodology/approach
This work carries out the irradiation test of the specimens and measures their S21 parameters before and after irradiation. A simulation model describing the total dose effect was built based on the experimental test results. And, the radiation hardening design is evaluated by the simulation method.

Findings
The experimental results demonstrate that the S21 curve of the interconnection decreases with the increase of the irradiation dose, indicating that the total dose effect leads to the decline of its signal transmission characteristics. According to the simulation results, decreasing the height of the through silicon via (TSV), increasing the radius of the TSV, reducing the length of Si and increasing the number of grounded through silicon via have positive effects on improving the radiation resistance of the interconnection structure.

Originality/value
This work investigates the effect of radiation on the transmission characteristics of interconnection structures for 3D packaging and proposes the hardening design methods. It is meaningful for improving the reliability of 3D packaging in space applications.
Uncomfortable science: How mathematical models, and consensus, come to be in public policy
Authors: Rhodes Tim , Lancaster Kari 
Published: September 2022

AbstractWe explore messy translations of evidence in policy as a site of ‘uncomfortable science’. Drawing on the work of John Law, we follow evidence as a ‘fluid object’ of its situation, also enacted in relation to a hinterland of practices. Working with the qualitative interview accounts of mathematical modellers and other scientists engaged in the UK COVID‐19 response, we trace how models perform as evidence. Our point of departure is a moment of controversy in the public announcement of second national lockdown in the UK, and specifically, the projected daily deaths from COVID‐19 presented in support of this policy decision. We reflect on this event to trace the messy translations of “scientific consensus” in the face of uncertainty. Efforts among scientists to realise evidence‐based expectation and to manage the troubled translations of models in policy, including via “scientific consensus”, can extend the dis‐ease of uncomfortable science rather than clean it up or close it down. We argue that the project of evidence‐based policy is not so much in need of technical management or repair, but that we need to be thinking altogether differently.
Achieving transformation to lean management systems in health care
Authors: Charns Martin P. , Lerner Barbara , Yakovchenko Vera , Urech Tracy H. , Shin Marlena H. , Kim Bo , Engle Ryann L. , Vashi Anita A. 
Published: September 2022

AbstractObjectiveTo understand what factors and organizational dynamics enable Lean transformation of health care organizations.Data SourcesPrimary data were collected through two waves of interviews in 2016–2017 with leaders and staff at seven veterans affairs medical centers participating in Lean enterprise transformation.Study DesignUsing an observational study design, for each site we coded and rated seven potential enablers of transformation. The outcome measure was the extent of Lean transformation, constructed by coding and rating 11 markers of depth and spread of transformation. Using multivalue coincidence analysis (CNA), we identified enablers that distinguished among sites having different levels of transformation. We identified representative quotes for the enablers.Data Collection MethodsWe interviewed 121 executive leaders, middle managers, expert consultants, systems redesign staff, frontline supervisors, and staff.Principal FindingsTwo sites achieved high Lean transformation, three medium, and two low. Together leadership support and capability development were sufficient for the three‐level Lean transformation outcomes with 100% consistency and 100% coverage. High scores on both corresponded to high Lean transformation; medium on either one corresponded to medium transformation; and low on both corresponded to low transformation. Additionally, low scores in communication and availability of data and very low scores in alignment characterized low‐transformation sites. Sites with high leadership support also had a high veteran engagement.ConclusionsThis multisite study develops a novel measure of the extent of organization‐wide Lean transformation and uses CNA to identify enablers linked to transformation. It provides insights into why and how some organizations are more successful at transformation than others. Findings support the applicability of the organization transformation model that guided the study and highlight the roles of executive leadership and capability development in the dynamics of transformation.
A systematic review of virtual reality therapies for substance use disorders: Impact on secondary treatment outcomes
Authors: Taubin Daria , Berger Amy , Greenwald Dan , Greenwald Herbert , Burke Colin , Gongora Dinah S. , Wilens Timothy 
Published: September 2022

AbstractBackground and ObjectivesVirtual reality (VR) therapy may be an effective tool in treating urges and cravings in substance use disorder (SUD). Given the high co‐occurrence of difficulties with mood, anxiety, and emotional dysregulation with SUD, this review sought to examine the extant literature on the efficacy of VR for SUD in improving these secondary treatment outcomes.MethodsA systematic literature review was conducted following PRISMA guidelines in PubMed, PsychInfo, and Embase. Studies were included if they utilized immersive VR, were conducted with individuals with substance use disorder/dependence/misuse, and included measures of mood, anxiety, depression, emotional dysregulation, or retention in treatment.ResultsSeven articles met our inclusion criteria. Five studies were conducted on patients using nicotine and utilized a cue‐exposure intervention. VR was effective at reducing substance use and cravings in the majority of studies. Results on the efficacy of VR for improving mood, anxiety, and emotional regulation were mixed. Work examining retention in treatment was limited.Discussion and ConclusionsVR for SUD has the potential to improve mood and anxiety symptoms as well as retention in treatment for patients with SUD, particularly if the therapy targets these psychological symptoms. Future studies examining components of VR for SUD in individuals with drug use disorders, as well as examinations of targeted interventions for associated mood, emotional dysregulation, and retention in treatment, are necessary.Scientific SignificanceThis is the first systematic review of the impact of VR on mood, anxiety, and emotional dysregulation for individuals with substance use.
Utilizing the same incision for staged renal transplant in patients with polycystic kidney disease requiring hand‐assisted laparoscopic nephrectomy
Authors: Huynh Nguyen , Yoon Peter , Hort Amy , Yao Jinna , Lee Taina , Yuen Lawrence , Laurence Jerome Martin , Pleass Henry 
Published: September 2022

AbstractBackgroundsMany autosomal dominant polycystic kidney disease (ADPKD) patients undergo nephrectomy and subsequent renal transplantation. We report our outcomes after hand‐assisted laparoscopic nephrectomy (HALN) where a Rutherford‐Morrison incision is used as a hand‐port site and kidney extraction site, as well the future incision site for staged transplantation.MethodsA retrospective review was performed on all adult nephrectomies for ADPKD by the Transplant Surgery department at Westmead Hospital between June 2011 and June 2021. Outcomes were compared between HALN, laparoscopic nephrectomy (LN) and open nephrectomy (ON) including operation time, hospital length of stay (LOS), post‐operative complications, subsequent transplantation and post‐transplantation wound complications.ResultsTwenty‐two HALN, 8 LN and 5 ON were performed during the study period. Median kidney weights for HALN, LN and ON were significantly different (1575, 403, 3420 g respectively, P = 0.001). There was a significant difference in LOS between the HALN and ON (5.8 versus 9.8 days, P = 0.04), but not between HALN and LN (5.8 versus 5.1, P = 0.06). There was no significant difference for operation time (P = 0.34) and major complication rates (P = 0.58). There were 8 HALN, 5 LN and 2 ON who have had subsequent renal transplantation with one wound complication, an incisional hernia in the HALN group.ConclusionOur HALN is associated with a shorter LOS and similar complication rate to ON and can be efficiently performed for significantly larger kidneys than LN without a significant difference in operation time or LOS. The same Rutherford‐Morrison incision site can be used for transplantation.
Diminishing lengths of subsequent bowel resections in the surgical management of ileal Crohn's disease
Authors: Maher Declan , Ting Pascallina , Edmundson Aleksandra , Cuda Tahleesa J. , Clark David A. 
Published: September 2022

AbstractBackgroundCrohn's disease is a chronic inflammatory bowel disease that most commonly affects the ileum. As a result, it is associated with a high lifetime risk of one or more surgical resections. The surgical paradigm is to preserve intestinal length. This study aims to assess the length of ileum resected at the index operation and at subsequent ileocolic resections for Crohn's disease.MethodsThis is a retrospective study assessing the clinical and pathological data of patients undergoing ileocolic resection for the management of Crohn's disease over the period 01/01/2002 to 31/07/2020 in two metropolitan Australian hospitals.ResultsOne hundred and seventy‐six patients were analysed: 130 underwent a single resection; 31 underwent two resections; and 15 underwent three resections. The median age at the first operation was 37.2 years (range 18–69) with 60% of patients female. The median length resected at the first surgery was 17.8 cm (IQR 12.0) for small bowel, and 5.0 cm (IQR 1.0) for large bowel. The length of ileum resected at the first surgery was significantly greater than that of the second (P = 0.0001), without significant differences between the second and third resections (P = 0.49). The time interval from diagnosis to the first surgery had no significant impact on the length of intestine resected at the index ileocolic resection.ConclusionIn Crohn's disease, the length of ileum removed at first resection is the greatest, with subsequent resection lengths less than the first.
TheAbeng’s Call: The Articulation of Place and the International in Black Power Print Production
Authors: Gowland Ben 
Published: September 2022

AbstractThis article engages with radical Black Power print production in order to examine the articulation of Black practices of place‐making and Black internationalist spatial politics. These spatial politics and practices are developed through engagement with the Jamaican Black Power newspaperAbengwhich was produced at the height of Black Power activity on the island in 1969. The paper draws on Black Geographies scholarship to demonstrate thatAbengrepresented a material and discursive means through which subaltern practices and places of resistance in Jamaica were enacted in opposition to and excess of plantation spatialities and regimes on the island. The carving out of such subaltern places allowed for the articulation of transnational imaginaries and translocal solidarities with similarly aligned communities and struggles across the diasporic world. TheAbengnewspaper was again central in crafting these imagined Black internationalist geographies and coeval praxes of transnational solidarity.
Inhibitory deficits and symptoms of attention‐deficit hyperactivity disorder: How are they related to effortful control?
Authors: Kostyrka‐Allchorne Katarzyna , Wass Sam V. , Yusuf Hodo , Rao Vidya , Bertini Chloé , Sonuga‐Barke Edmund J. S. 
Published: September 2022

AbstractSeparate studies with clinical and community‐based samples have identified an association between symptoms of attention‐deficit hyperactivity disorder (ADHD) and inhibitory control deficits and ADHD and weak effortful control. We tested whether differences in effortful control explained the associations between ADHD symptoms and inhibitory control deficits, controlling for conduct problems. In a community sample, parents rated ADHD symptoms, conduct problems, effortful control, surgency and negative affect in 77 4‐7‐year‐olds (47 girls), who performed an inhibitory control task. ADHD symptoms, deficient inhibitory control and low effortful control were correlated. Controlling for conduct problems, path analysis showed the ADHD symptoms – inhibitory control link was mediated statistically by effortful control. This focuses attention on cognitive‐energetic factors associated with ADHD‐related executive deficits.
Perivascular macrophages in theCNS: From health to neurovascular diseases
Authors: Zheng Li , Guo Yunlu , Zhai Xiaozhu , Zhang Yueman , Chen Weijie , Zhu Ziyu , Xuan Wei , Li Peiying 
Published: September 2022

AbstractBrain perivascular macrophages (PVMs) are attracting increasing attention as this emerging cell population in the brain has multifaced roles in supporting the central nervous system structure, brain development, and maintaining physiological functions. They also widely participate in neurological diseases such as neurodegeneration and ischemic stroke. Moreover, PVMs have been reported to have both beneficial and detrimental effects under different pathological contexts. Advanced research technologies allowed the further in‐depth study of PVMs and revealed novel concepts in their origins, differentiation, and regulatory mechanisms. Deepened understanding of the roles of PVMs in different brain pathological conditions can reveal novel phenotypic changes and regulatory signaling, which might pave the way for the development of novel treatment strategies targeting PVMs.
Prospective and multicentre study of radiofrequency treatment in anal fistula
Authors: Sautereau Marie , Bouchard Dominique , Brochard Charlène , Pigot François , Siproudhis Laurent , Fayette Jean Marie , Train Cécile , Laurain Anne , Favreau Charlotte , Abramowitz Laurent 
Published: September 2022

AbstractBackgroundThe most effective treatment for anal fistula is fistulotomy, but it involves a risk of anal incontinence. To reduce this morbidity, sphincter‐sparing treatments have been developed, but their success in real life is often less than 50%. The aim is to determine the clinical healing rate 6 months after radiofrequency treatment.MethodsWe planned to evaluate 50 patients from three French proctology centres. Treatment efficacy was evaluated at 6 and 12 months by means of clinical and magnetic resonance imaging examination. We evaluated morbidity and healing prognostic factors.ResultsFifty patients with a mean age of 51 years (22–82) were included. Eleven patients had a low trans‐sphincteric fistula (LTS), 21 patients had a high trans‐sphincteric fistula (HTS), eight had a complex fistula and nine had Crohn's disease fistula. After 6 months, 17 patients (34.7%) had a clinically healed fistula, including five (45.5%) with LTS fistula, seven (33.3%) with HTS fistula, one (12.5%) with complex fistula, four (44.4%) with Crohn's disease, with no significant difference between these fistula types (p: 0.142). At 12 months, the healing rate was identical. MRI in 15 out of 17 clinically healed patients showed a deep remission of 73.3% at 12 months. Energy power was associated with the success of the treatment. There was an 8.2% incidence of post‐surgical complications with 4.1% being abscesses (one required surgical management). Postoperative pain was minor. No new cases or deterioration of continence have been shown.ConclusionRadiofrequency is effective in 34.7% of the cases as an anal fistula treatment in this first prospective study, with low morbidity and no effect on continence. Clinical healing was deep (MRI) in three‐quarters at 1 year. The increase in energy power during the procedure seems to be a key point to be analysed to optimise results.
Pharmacokinetic evaluation of radiolabeled intraocular anti‐CLEC14a antibody in preclinical animal species and application in humans
Authors: Park Sohyun , Lee Youn Woo , Oh Jaeseong , Kim Su Jin , Lee Sukmook , Lee Ho‐Young 
Published: September 2022

AbstractAnti‐angiogenic antibodies are widely used in the treatment of neovascular macular degeneration. Human antibody targeting C‐type lectin domain family 14 member A (CLEC14a) is potential therapeutic agents owing to its antiangiogenic activity. In the present study, we aimed to predict the human intraocular pharmacokinetic (PK) properties of an anti‐CLEC14a antibody. I‐125 labeled aflibercept and anti‐CLEC14a antibody were intravitreally injected into mice, rats, and rabbits. Single photon emission computed tomography/computed tomography imaging was performed, and the intraocular radioactivity concentration (%ID/ml) was obtained. The PK parameters in those three animal species were obtained by compartmental analysis. The PK parameters in humans were estimated by allometric scaling of the animal PK parameters with consideration of the hydrodynamic radius of the antibody. The mean half‐life values of intraocular I‐125‐labeled aflibercept in mice, rats, and rabbits were 1.13 days, 1.25 days, and 4.91 days, respectively, by analysis with a one‐compartment model. The predicted human half‐life of intraocular aflibercept was 5.75 days based on vitreal volume by allometric scaling. The half‐life values of intraocular I‐125‐labeled anti‐CLEC14a in mice, rats and rabbits were 1.05 days, 1.84 days, and 6.37 days, respectively, by analysis with a one‐compartment model. The predicted human half‐life of intraocular anti‐CLEC14a was 10.29 days based on vitreal volume. According to the hydrodynamic volume of the anti‐CLEC14a, the predicted human half‐life of intraocular anti‐CLEC14a was 9.81 days. The PK characteristics of the intraocular anti‐CLEC14a antibody were evaluated noninvasively in animals using I‐125 labeling, and the intraocular PK characteristics in humans were predicted using these animal data. This methodology can be applied for the development of new antiangiogenic antibodies to treat macular degeneration.