bluuebunny/crossref_metadata_2025_split huggingface dataset:
Strictly conformal transformation optics for directivity enhancement and unidirectional cloaking of a cylindrical wire antenna
Authors: Eskandari Hossein 
Published: September 2022

AbstractUsing conformal transformation optics, a cylindrical shell made of an isotropic refractive index material is designed to improve the directivity of a wire antenna while making it unidirectionally invisible. If the incident wave comes from a specific direction, it is guided around the wire. Furthermore, when an electrical current is used to excite the wire, the dielectric shell transforms the radiated wave into two lateral beams, improving directivity. The refractive index of the dielectric shell is calculated using the transformation optics recipe after establishing a closed-form conformal mapping between an annulus and a circle with a slit. The refractive index is then modified and discretized using a hexagonal lattice. Ray-tracing and full-wave simulations with COMSOL Multiphysics are used to validate the functionality of the proposed shell.
BMP2 promotes lung adenocarcinoma metastasis through BMP receptor 2-mediated SMAD1/5 activation
Authors: Wu Cheng-Kuei , Wei Man-Ting , Wu Hung-Chang , Wu Cheng-Lin , Wu Cheng-Ju , Liaw Hungjiun , Su Wen-Pin 
Published: September 2022

AbstractBone morphogenetic protein 2 (BMP2) is highly overexpressed in human non-small cell lung cancer (NSCLC) and correlates with tumor stage and metastatic burden. Although several lines of evidence suggest that BMP2 promotes cell migration and invasiveness in vitro, the in vivo role of BMP2 in the metastasis of lung adenocarcinoma cells remains less well understood. Here, we revealed that BMP2 is highly overexpressed in lung adenocarcinoma patients with lymph node metastasis compared with patients without lymph node metastasis. Using an in vivo orthotopic mouse model, we clearly demonstrated that BMP2 promotes lung adenocarcinoma metastasis. The depletion of BMP2 or its receptor BMPR2 significantly reduced cell migration and invasiveness. We further identified that BMP2/BMPR2-mediated cell migration involves the activation of the SMAD1/5/8 signaling pathway, independent of the KRAS signaling pathway. Significantly, the depletion of SMAD1/5/8 or the inhibition of SMAD1/5/8 by LDN193189 inhibitor significantly reduced cell migration. These findings show that BMP2 promotes NSCLC metastasis, indicating that targeting the BMP2 signaling pathway may represent a potential therapeutic strategy for treating patients with metastatic NSCLC.
Social closeness modulates brain dynamics during trust anticipation
Authors: Jiménez Said , Mercadillo Roberto E. , Angeles-Valdez Diego , Sánchez-Sosa Juan J. , Muñoz-Delgado Jairo , Garza-Villarreal Eduardo A. 
Published: September 2022

AbstractAnticipation of trust from someone with high social closeness is expected. However, if there is uncertainty in the interaction because a person is a stranger or because he has distrusted us on another occasion, we need to keep track of his behavior and intentions. Using functional Magnetic Resonance Imaging (fMRI) we wanted to find the brain regions related to trust anticipation from partners who differ in their level of social closeness. We designed an experiment in which 30 participants played an adapted trust game with three trustors: A computer, a stranger, and a real friend. We covertly manipulated their decisions in the game, so they trusted 75% of the trials and distrusted in remaining trials. Using a psychophysiological interaction analysis, we found increases in functional coupling between the anterior insula (AIns) and intra parietal sulcus (IPS) during trust anticipation between a high versus low social closeness partner. Also, the right parietal cortex was coupled with the fusiform gyrus (FG) and the inferior/middle temporal gyrus during trust anticipation of a friend versus a stranger. These results suggest that brain regions involved in encoding the intentions of others are recruited during trust anticipation from a friend compared to a stranger.
Necroptosis-related lncRNA signature predicts prognosis and immune response for cervical squamous cell carcinoma and endocervical adenocarcinomas
Authors: Lin Zhiheng , Zou Jiani , Sui Xiaohui , Yao Shujuan , Lin Lidong , Wang Jiuling , Zhao Junde 
Published: September 2022

AbstractNecroptosis, a programmed form of necrotic cell death, plays critical regulatory roles in the progression and metastatic spread of cancers such as cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC). However, there are few articles systematically analyzing the necroptosis-related long non-coding RNAs (NRlncRNAs) correlated with CESC patients. Both RNA-sequencing and clinical data of CESC patients are downloaded from TCGA database in this study. Pearson correlation analysis, least absolute shrinkage, operator algorithm selection and Cox regression model are employed to screen and create a risk score model of eleven-NRlncRNAs (MIR100HG, LINC00996, SNHG30, LINC02688, HCG15, TUBA3FP, MIAT, DBH-AS1, ERICH6-AS1SCAT1, LINC01702) prognostic. Thereafter, a series of tests are carried out in sequence to evaluate the model for independent prognostic value. Gene set enrichment analytic paper, Gene Ontology analysis, Kyoto Encyclopedia of Genes and Genomes pathway enrichment analytic paper make it clear that immune-related signaling pathways are very rich in the high-risk subgroup. Additionally, the prognostic risk score model is correlated to immune cell infiltration, potential immune checkpoint, immune function, immune micro-environmental and m6A-related gene. Mutation frequency in mutated genes and survival probability trend are higher in the low-risk subgroup in most of test cases when compared to the high-risk subgroup. This study constructs a renewed prognostic model of eleven-NRlncRNAs, which may make some contribution to accurately predicting the prognosis and the immune response from CESC patients, and improve the recognition of CESC patients and optimize customized treatment regimens to some extent.
Polyethylenglycol – Freund oder Feind?
Authors: Bayerl Christiane , Herbst Matthias 
Published: September 2022

ZusammenfassungAnaphylaktische Reaktionen nach Impfungen sind selten. Zwei Fälle von Reaktionen nach der Pfizer-BioNTech-Covid-19-Vakzine, BNT162b2, wurden aus dem UK berichtet, weitere 19 aus den USA. Als möglicher Auslöser wurde Polyethylenglycol (PEG) angeschuldigt. Pegylierung ist ein üblicher Vorgang in der Impfstoffherstellung, um die Substanzen vor schnellem immunologischem Abbau zu schützen. PEG ist ein Polyether (Synonyme z. B. Laureth-9, Polidocanol, Thesit, Macrogol) und findet sich in Kosmetika, Körperpflegeprodukten, Nahrungsmitteln, Liposomen und Nanopartikeln als Drug-Delivery-Systeme für Medikamente und als osmotisches Laxans vor Gastro-/Koloskopien. IgM-Antikörper auf PEG werden bei 70% der Bevölkerung nachgewiesen. Bei 2 Fällen von Soforttyp-Reaktionen auf PEG fanden sich IgE-Antiköper, bei anderen Medikamentengaben mit PEG geht man von pseudoallergischen Reaktionen über die Komplement-Aktivierungs-related Pseudoallergie (CARPA) aus. In Relation zum weit verbreiteten Einsatz von PEG sind die Impfreaktionen sehr selten und aktuell kein Grund, Allergiker oder Menschen mit Anaphylaxien bei entsprechenden Vorsichtsmaßnahmen auf bekannte Auslöser auszuschließen. Aufgrund der Meldepflicht (Gesundheitsamt und Arzneimittelkommission der deutschen Ärzteschaft) ist bald mit weiteren Erkenntnissen zu rechnen.
Nomenklatur für Nierenfunktion und Nierenkrankheiten – Durch Präzision und Verständlichkeit zu besserer Erfassung und Prognose
Authors: Eckardt Kai-Uwe , Binet Isabelle , de Groot Kirsten , Floege Jürgen , Galle Jan C. , Jordans Isabelle , Kribben Andreas , Oberbauer Rainer , Pavenstädt Hermann , Rosenkranz Alexander , Säemann Marcus , Winkelmayer Wolfgang C. 
Published: September 2022

ZusammenfassungNierenkrankheiten stellen ein zunehmendes Gesundheitsproblem dar, dessen Eindämmung eine effektive Kommunikation zwischen den an Erfassung, Diagnostik und Therapie Beteiligten sowie den betroffenen Patientinnen und Patienten erfordert. Die Nomenklatur für Nierenfunktion und Nierenkrankheiten ist jedoch bislang nicht einheitlich. Die internationale, gemeinnützige Organisation Kidney Disease: Improving Global Outcomes (KDIGO) hat deshalb 2019 in einem Konsensus-Prozess ein englischsprachiges Glossar entwickelt, um die Begriffe zur Beschreibung von Nierenfunktion, Nierenstruktur und Nierenkrankheiten zu vereinheitlichen. Leitprinzipien bei der Entwicklung dieser Nomenklatur waren (1) Präzision, (2) Patientenzentrierung und (3) Konsistenz mit bisherigen KDIGO-Leitlinien. Das vorliegende Positionspapier beinhaltet eine deutsche Übersetzung dieses Glossars, die im Auftrag der nephrologischen Fachgesellschaften in Deutschland, Österreich und der Schweiz entwickelt wurde.
Evaluation of activity kinetics in breast milk and calculation of the resulting effective radiation dose after 99mTc-MIBI scintigraphy of a breastfeeding women
Authors: Happel Christian , Gröner Daniel , Kranert Wolfgang Tilman , Grünwald Frank 
Published: September 2022

Abstract
Introduction In breastfeeding women, the indication for scintigraphic imaging is strongly restricted due to potential transition of the radiopharmaceutical to the child via breast milk. The potential activity uptake of the breastfed child depends on the chemical compound of the radio pharmaceutical as well as biokinetics and metabolism in the maternal body.
Methods In the presented case <sup>99m</sup>Tc-MIBI scintigraphy was performed in a breastfeeding woman with sonographically suspicious thyroid nodules. Breastfeeding was interrupted for 30 hours and the breast milk during this period was collected and analysed to determine the excreted activity and the potentially resulting dose to the breastfed child.
Results Activity concentration in the first breast milk sample (1.83 hours after administration of 500 MBq <sup>99m</sup>Tc-MIBI) was 380 Bq/mL, resulting in an absolute activity of 50 kBq for a sample size of 132 mL. Subsequently activity concentration decreased to 6 Bq/mL (29.8 hours p.i.). The calculated effective half-life of the secretion of <sup>99m</sup>Tc-MIBI via breast milk was 4.7 hours. The potentially resulting effective dose for the breastfed child was 13.4 µSv (ICRP80: dose coefficient: 0.13 mSv/MBq for <sup>99m</sup>Tc).
Conclusion Time activity curve showed a rapid decrease of the <sup>99m</sup>Tc-MIBI activity secreted to the breast milk. More than 90 % of the total secreted activity is attributable to the first 12 hours after administration. Therefore, an interruption of breastfeeding of 24 hours seems to be adequate.
Role of the optic nerve sheath diameter in the assessment of the effectiveness of decompressive surgery after malignant middle cerebral artery infarction
Authors: Senol Ozgur , Cosgun Zeliha , Dagistan Emine , Demiryurek Bekir Enes , Cancan Seckin Emre 
Published: September 2022

Abstract
Background After a case of stroke, intracranial pressure (ICP) must be measured and monitored, and the gold standard method for that is through an invasive technique using an intraventricular or intraparenchymal device. However, The ICP can also be assessed through a non-invasive method, comprised of the measurement of the optic nerve sheath diameter (ONSD) through ultrasound (US).
Objective To evaluate the ICP of patients who underwent wide decompressive craniectomy after middle cerebral artery (MCA) infarction via preoperative and postoperative ONSD measurements.
Methods A total of 17 patients, aged between 34 and 70 years, diagnosed with malignant MCA infarction with radiological edema and mid-line shift, who underwent decompressive surgery, were eligible. From the records, we collected data on age, sex, preoperative and postoperative Glasgow Coma Scale (GCS) scores, National Institutes of Health Stroke Scale (NIHSS) score, the degree of disability in the preoperative period and three months postoperatively through the scores on the Modified Rankin Scale (MRS), and the preoperative and postoperative midline shift measured by computed tomography (CT) scans of the brain.
Results Preoperatively, the mean GCS score was of 8 (range: 7.7–9.2), whereas it was found to be of 12 (range 10–14) on the first postoperative day (p = 0.001). The mean preoperative NIHSS score was of 21.36 ± 2.70 and, on the first postoperative day, it was of 5.30 ± 0.75 (p < 0.001). As for the midline shift, the mean preoperative value was of 1.33 ± 0.75 cm, and, on the first postoperative day, 0.36 ± 0.40 cm (p < 0.001). And, regarding the ONSD, the mean preoperative measurement was of 5.5 ± 0.1 mm, and, on the first postoperative day, it was of 5 ± 0.9 mm (p < 0.001).
Conclusion The ocular US measurement of the ONSD for the preoperative and postoperative monitoring of the ICP seems to be a practical and useful method.
Clot Waveform Analysis for Monitoring Hemostasis
Authors: Nogami Keiji 
Published: September 2022

AbstractClot waveform analysis (CWA) is a recently developed global coagulation assessment, based on the continuous observation of changes in light transmittance, absorbance, or light scattering that occurs as fibrin formed in a plasma sample during routine clotting tests such as activated partial thromboplastin time (aPTT) and prothrombin time (PT). CWA can utilize qualitative waveform patterns as well as sensitive quantitative parameters and can be used as a simple method to assess global hemostasis, and can be applied to various challenging clinical situations. Although not all coagulation analyzers currently in use are able to provide CWA, the number of analyzers available to do so is increasing, as the usefulness of this process has become more widely recognized. CWA can be based on the coagulation mechanism of aPTT, an intrinsic trigger, and this has been reported in many studies, including diagnosis and treatment of patients with hemophilia, disseminated intravascular coagulation, and monitoring of anticoagulants and thrombosis. CWA using trace amounts of tissue factors also has the potential to expand the applications of this technology. Recently, there have been reports of the combined evaluation of fibrinolytic dynamics. Among the existing global coagulation assays, CWA may prove to be the easiest to standardize in clinical practice. However, more extensive testing using standardized methods in various clinical settings is needed to determine the true role of CWA in the evaluation of hemostasis and thrombosis in the future.
Platelet Function in Acute Kidney Injury: A Systematic Review and a Cohort Study
Authors: Jensen Jeppe Lundholm Stadarfeld , Hviid Claus Vinter Bødker , Hvas Christine Lodberg , Christensen Steffen , Hvas Anne-Mette , Larsen Julie Brogaard 
Published: September 2022

AbstractAcute kidney injury (AKI) patients have increased bleeding risk, which could be partially due to acquired platelet dysfunction. We conducted a systematic review and a cohort study to investigate platelet function and count in AKI and their association with AKI-related bleeding and mortality. Through a systematic literature search in PubMed and Embase, we identified 9 studies reporting platelet function and 56 studies reporting platelet count or platelet indices in AKI patients. Overall, platelet aggregation was reduced in AKI patients in nonintensive care unit (ICU) settings but not in ICU settings, except that reduced aggregation was associated with renal replacement therapy. Thrombocytopenia in AKI was frequent and often predictive of mortality. In our cohort study, we prospectively included 54 adult ICU patients who developed AKI within 24 hours of ICU admission and 33 non-AKI ICU controls. Platelet function was measured with light transmission aggregometry and flow cytometry. AKI patients bled more frequently than non-AKI patients (p = 0.04), and bleeding was associated with increased 30-day mortality in AKI (p = 0.02). However, platelet function was not different between AKI and non-AKI patients (aggregation: all p > 0.52; flow cytometry: all p > 0.07) and platelet function was not associated with bleeding in AKI. In conclusion, a reduced platelet count is frequent in AKI, but the literature on platelet function in AKI is sparse. In a cohort study, we demonstrated that patients with AKI within 24 hours of ICU admission exhibited increased bleeding tendency but this was not associated with reduced platelet function.
Gender, language, and representation in the United States Senate
Authors: Windsor Leah , Mitchell Sara McLaughlin , Osborn Tracy , Dietrich Bryce , Hampton Andrew J. 
Published: September 2022

Abstract
We explore how gendered language in Senate floor debates evolves between the 101st and 109th sessions (N=229,526 speeches). We hypothesize that female Senators speak like women in the general population, that their speeches focus on traditionally designated women’s issues, and that they use female linguistic strategies found in the general population when discussing low politics or women’s issues. We also expect women to speak like legislators, adopting more male linguistic approaches for high politics issues or in election year speeches and for female senators to use more male linguistics as time served in the Senate increases. Using a suite of computational linguistics approaches such as topic modeling (Latent Dirichlet Allocation), syntax and semantic analysis (Coh-Metrix), and sentiment analysis (LIWC), our analyses highlight the distinct roles of women speaking for women (e.g. promoting issues like education or healthcare), women speaking like women (e.g. using personal pronouns), and women speaking as Senators.
Development of a modified thermal humidity index and its application to human thermal comfort of urban vegetation patches
Authors: Zheng Xiaorou , Zhang Na , Wang Xin 
Published: September 2022

ABSTRACT
Extremely hot environments can trigger serious health problems. To evaluate the effects of microclimate on thermal comfort, we proposed and validated a modified thermal humidity index (MTHI) that combined air temperature and relative humidity with land surface temperature (LST). MTHI was more sensitive to microclimate changes than the general thermal humidity index that includes only T and RH, and thus the thermal comfort could be better indicated. In an urban riparian buffer study, we estimated the temporal dynamics and spatial distribution of MTHI values for 47 vegetation patches and explored how structural characteristics of patches affect the thermal comfort. The results showed that planting could significantly reduce LST and MTHI. Vegetation patches with complex vertical structures had considerably higher thermal comfort than those with simple structures. Decreasing nearest distance to river or increasing plant abundance could reduce the thermal discomfort. There were significant differences in the structure characteristics between the patches with MTHI <70 and those with MTHI >70, implying the critical thresholds of variations in thermal comfort with patch structure. Given that people always feel uncomfortable during the daytime in July, optimizing the patch structure is essential to improve the microclimate regulation services of an urban landscape.
Supplementary comparison for the traceability in high voltage capacitance and dissipation factor measurements (EURAMET.EM-S34)
Authors: Simón P , Hällström J , Bergman A 
Published: September 2022

Main text
The intercomparison consisted of calibrating the capacitance and loss factor (tan δ) of a set of reference capacitors at different voltage levels, including high voltage up to 200 kV, for frequencies between 50 Hz and 1kHz in low voltage measurements and 50 Hz in high voltage measurements.
The travelling standards consisted of a set of four reference capacitors (TRC) with fixed input and grounding leads and the corresponding connection cables of the following rated characteristics:
* System 1: 100 pF and rated voltage of 200 kV.
* System 2: 100 pF and rated voltage of 700 V.
* System 3: 500 nF and rated voltage of 10 V.
* System 4: 5000 nF and rated voltage of 10 V.
The coordinating laboratory was LCOE (Spain) and the participating institutes were LNE (France), VTT MIKES (Finland), RISE (Sweden), TÜBITAK UME (Türkiye), PTB (Germany) and LCOE (Spain). Participants used their best measurement procedures and setups in order to achieve their best calibration capabilities.
Some of the institutes did not perform all the measurements, therefore comparison reference values are based sometimes in the results of only 4 institutes.
Not all the laboratories measured at the same ambient temperature; to prevent this inconvenience and to be able to compare results, all capacitance values were corrected at 23 °C. The long drift of the high voltage capacitor of system 1, probably due to some small SF6 leakage, was also considered to calculate the CRV of each institute. Very good agreement between institutes is obtained for high voltage capacitance measurements (high voltage capacitance coefficient determination) and for low or high voltage dissipation factor measurements. Only a few low voltage measurements of capacitance are considered not compatible.
Undertaking the work collaboratively through EURAMET proved to be an excellent tool to compare calibration and measurement capabilities of NMI and DI, as well as an opportunity for several institutes to improve their CMCs.
To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database https://www.bipm.org/kcdb/.
The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Switchable fast-slow light in a cavity-magnon system by adding a squeezed drive field
Authors: Pei Yu-Kun , Yin Miao 
Published: September 2022

Abstract
We theoretically discuss the influence of a squeezed drive on the fast and slow light effect at different temperatures by focusing on two main factors: the nonlinear gain coefficient of optical parametric amplification and the phase of the pumping field. We show that the nonlinear gain coefficient and the phase of the pump field will affect the coupling strength between photon and magnon, which provides a way to achieve more obvious fast and slow light effects and good potential to realize the fast-slow light conversion. Moreover, by comparing two different temperatures, we find that the low temperature environment is more conducive to the production of fast light and slow light. With the addition of the squeezing drive field, the group delay of the system will get a larger value and the symmetry of the system will be destroyed, leading to asymmetric absorption. Our results provide more freedom for the realization and conversion of fast and slow light and is expected to find applications in optical communication and optical storage.
Magnetic phase diagram of a 2-dimensional triangular lattice antiferromagnet Na2BaMn(PO4)2
Authors: Kim Jaewook , Kim Kyoo , Choi Eunsang , Joon Ko Young , Woo Lee Dong , Ho Lim Sang , Hoon Jung Jong , Lee Seungsu 
Published: September 2022

Abstract
We report the magnetic phase transitions of a spin-5/2, 2-dimensional triangular lattice antiferromagnet (AFM) Na2BaMn(PO4)2. From specific heat measurements, we observe two magnetic transitions at temperatures 1.15 and 1.30 K at zero magnetic field. Detailed AC magnetic susceptibility measurements reveal multiple phases including the

↑↑↓

(up-up-down)-phase between 1.9 and 2.9 T at 47 mK when magnetic field is applied along the c axis, implying that Na2BaMn(PO4)2 is a classical 2d TL Heisenberg AFM with easy-axis anisotropy. However, it deviates from an ideal model as evidenced by a hump region with hysteresis between the

↑↑↓

and V-phases and weak phase transitions. Our work provides another experimental example to study frustrated magnetism in 2d TL AFM which also serves as a reference to understand the possible quantum spin liquid behavior and anomalous phase diagrams observed in sibling systems Na2BaM(PO4)2 (M = Co, Ni).