bluuebunny/crossref_metadata_2025_split huggingface dataset:
Arterial Spin Labeling‐Based MRI Estimation of Penumbral Tissue in Acute Ischemic Stroke
Authors: Lyu Jinhao , Duan Qi , Xiao Sa , Meng Zhihua , Wu Xiaoyan , Chen Wen , Wang Guohua , Niu Qingliang , Li Xin , Bian Yitong , Han Dan , Guo Weiting , Yang Shuai , Bian Xiangbing , Lan Yina , Wang Liuxian , Zhang Tingyang , Duan Caohui , Zhang Dekang , Wang Xueyang , Chen Ling , Tian Chenglin , Zhou Xin , Lou Xin ,   the MR‐STARS Investigators
Published: July 2022

BackgroundArterial spin labeling (ASL) has shown potential for the assessment of penumbral tissue in patients with acute ischemic stroke (AIS). The postlabeling delay (PLD) parameter is sensitive to arterial transit delays and influences cerebral blood flow measurements.PurposeTo assess the impact of ASL acquisition at different PLDs for penumbral tissue quantification and to compare their performance regarding assisting patient selection for endovascular treatment with dynamic susceptibility contrast MRI (DSC‐MRI) as the reference method.Study TypeRetrospective.PopulationA total of 53 patients (59.98 ± 12.60 years, 32% women) with AIS caused by internal carotid or middle cerebral artery occlusion.Field Strength/SequenceA 3‐T, three‐dimensional pseudo‐continuous ASL with fast‐spin echo readout.AssessmentHypoperfusion volume was measured using DSC‐MRI and ASL with PLDs of 1.500 msec and 2.500 msec, respectively. Eligibility for endovascular treatment was retrospectively determined according to the imaging criteria of the Endovascular Therapy Following Imaging Evaluation for Ischemic Stroke trial (DEFUSE 3).Statistical TestsKruskal–Wallis tests, Bland–Altman plots, Cohen's kappa, and receiver operating characteristic analyses were used. The threshold for statistical significance was set at P ˂ 0.05.ResultsHypoperfusion volume for ASL with a PLD of 1.500 msec was significantly larger than that for DSC‐MRI, while the hypoperfusion volume for a PLD of 2.500 msec was not significantly different from that of DSC‐MRI (P = 0.435). Bland–Altman plots showed that the mean volumetric error between the hypoperfusion volume measured by DSC‐MRI and ASL with PLDs of 1.500/2.500 msec was −107.0 mL vs. 4.49 mL. Cohen's kappa was 0.679 vs. 0.773 for DSC‐MRI and ASL, respectively, with a PLD of 1.500/2.500 msec. The sensitivity and specificity for ASL with a PLD of 1.500/2.500 msec in identifying patients eligible for treatment were 89.74% vs. 97.44% and 92.86% vs. 64.29%, respectively.Data ConclusionIn AIS, PLDs for ASL acquisition may have a considerable impact on the quantification of the hypoperfusion volume.Evidence Level3Technical EfficacyStage 2
Draft genome sequence of Pseudomonas sp. A46 isolated from mercury‐contaminated wastewater
Authors: Lo Kai‐Hung , Lu Che‐Wei , Liu Fu‐Guo , Kao Chih‐Ming , Chen Ssu Ching 
Published: July 2022

AbstractPseudomonas sp. A46 was first isolated from mercury‐contaminated groundwater in Taiwan. This study is the first to report the draft whole‐genome sequence of Pseudomonas sp. A46. Its genome consists of 126 contigs, with a total length of 6,782,516 bp and a GC content of 64.7%. Phylogenetic analysis based on 16 S rRNA gene sequences revealed that Pseudomonas sp. A46 is closely related to Pseudomonas citronellolis. Assessment of the draft genome sequence revealed that Pseudomonas sp. A46 harbors sets of genes conferring resistance to heavy metals, such as mercury, zinc, lead, copper, cadmium, chromate, and arsenate. These identified genes enable this bacterium to tolerate heavy metal stress.
Need for speed, but how much does it cost? Unpacking the fee‐speed relationship in Bitcoin transactions
Authors: Shang Guangzhi , Ilk Noyan , Fan Shaokun 
Published: July 2022

AbstractThe growing popularity of blockchain‐based cryptocurrencies is driven by the flexibility in transaction fee offerings, among other factors. To achieve service‐level differentiation among their users, many cryptocurrencies allow users to “name your own price,” giving rise to a large variation in fee offerings and hence, variation in confirmation times. Yet, the time it takes a cryptocurrency transaction to be confirmed in the blockchain is not only affected by the fee offered, but also by the contemporaneous congestion level and the inherent randomness in the verification process. Although it is generally expected that higher fees lead to quicker confirmation, the uniqueness of the cryptocurrency setting adds important nuances to the fee‐speed relationship. Using Bitcoin—the original and most heavily used cryptocurrency by far—as our empirical context, we stylize the transaction confirmation processes, propose a theoretical framework that maps the causal path from fee to speed, and estimate this framework using Bitcoin transaction data under periods of high volatility. Our results show strong evidence for two characteristics of fee's impact: congestion dependence and tail shrinkage. Our finding that the speed acceleration effect of fee is particularly strong on the tail of the confirmation time distribution motivates a target service level approach to fee recommendation. To put this finding into practice, we develop an efficient computational procedure that helps Bitcoin users accurately estimate fees based on their confirmation delay preferences. We discuss the implications of our analyses on future cryptocurrency development and the long‐term adoption of this revolutionary technology.
Effects of ε‐polylysine and chitooligosaccharide Maillard reaction products on quality of refrigerated sea bass fillets
Authors: Lang Ai , Lan Weiqing , Gu Yongji , Wang Zhicheng , Xie Jing 
Published: July 2022

AbstractBACKGROUNDThe Maillard reaction is a promising and safe method for obtaining chitooligosaccharide conjugates with proteins or peptides as food preservatives. This study aims to investigate the moisture state, physicochemical properties, and shelf‐life of sea bass fillets treated with ε‐polylysine (ε‐PL) and chitooligosaccharides (COS), which are Maillard reaction products (LC‐MRPs), during refrigerated storage.RESULTSThe results of microbiological analysis and confocal laser scanning microscope (CLSM) revealed that LC‐MRPs could retard microbial growth effectively. Compared with control, other treated groups could strongly retard the increase in the thiobarbituric acid (TBA) value, the K‐value and the total volatile basic nitrogen (TVB‐N) value, and also inhibited the softening of texture and the accumulation of biogenic amines in fish. The results of low‐field nuclear magnetic resonance (LF‐NMR) and magnetic resonance imaging (MRI) indicate that LC‐MRPs could delay the water migration of fillets and increase water holding capacity (WHC). Through sensory evaluation, the application of LC‐MRPs increased the shelf‐life of refrigerated sea bass fillets for another 9 days.CONCLUSIONMaillard reaction products derived from chitooligosaccharides and ε‐polylysine have strong potential for preserving sea bass. © 2022 Society of Chemical Industry.
Effect of Entanglement Density on Mechanical Properties and the Deformation Mechanism of Rubber‐Modified PPO/PS Blends
Authors: Song Lixin , Zhang Yu , Ren Jiannan , Li Yongchao , Yang Bing , Xing Enhan , Wang Yuanxia , Shi Ying 
Published: July 2022

AbstractThis paper presents the synthesis of core‐shell polybutadiene‐graft‐polystyrene (PB‐g‐PS) with a core‐shell ratio of 70/30 in the copolymer. The polyphenylene oxide (PPO)/polystyrene (PS) alloy is toughened by high‐impact polystyrene (HIPS) and the PB‐g‐PS copolymer. The effect of entanglement density on the mechanical properties and the deformation mechanism of the blends is investigated. The entanglement density of the blends is found to increase with increasing PPO content. The mechanical properties of the blends indicated that HIPS and PB‐g‐PS have excellent synergic toughening effects on the PPO/PS alloy, and the impact strength and elongation at break gradually increased with increasing matrix chain entanglement density. When the chain entanglement density of the matrix is low, the deformation mechanism of the blends is multiple crazing. As the chain entanglement density of the matrix increased, there are two deformation mechanisms in the blends at the same time: crazing and shear yield. However, the crazing disappeared when the chain entanglement density of the matrix reached a certain value, and only shear yield existed. Therefore, with the increase of matrix entanglement density in the blends, the deformation mechanism of the blends gradually transitioned from crazing to shear yield and cavitation, enhancing the toughness of the blends.
Dual Post‐Treatments Boost Thermoelectric Performance of PEDOT:PSS Films and Their Devices
Authors: Wu Ting , Shi Xiao‐Lei , Liu Wei‐Di , Sun Shuai , Liu Qingfeng , Chen Zhi‐Gang 
Published: July 2022

AbstractOwing to intrinsically high electrical conductivity and low thermoelectric conductivity, poly(3,4‐ethylenedioxithiophene):poly(styrenesulfonate) (PEDOT:PSS) shows promising thermoelectric properties. However, its relatively low power factor limits the practical applications of PEDOT:PSS. Here, unique dual post‐treatments by sodium sulfite (Na2SO3) and formamide (CH3NO) to boost the thermoelectric performance of flexible PEDOT:PSS films with an optimized power factor of 74.09 µW m–1 K–2 are used. Comprehensive characterizations confirm that CH3NO reduces the excessive insulating PSS and thereby increases the electrical conductivity, while Na2SO3 lowers the reduction of the doping level of PEDOT, leading to an increased Seebeck coefficient. Furthermore, the rationally post‐treated PEDOT:PSS films are assembled into a flexible thermoelectric device that exhibits an open‐circuit voltage of 2.8 mV using the heat from the human arm and an output power density of 2.56 µW cm–2 by a temperature difference of 25 K, indicating great potential for practical applications on sustainably charging low‐grade wearable electronics.
Depredation of Demersal Reef Fishes Released with Descender Devices Is Uncommon off North Carolina, USA
Authors: Runde Brendan J. , Rudershausen Paul J. , Bacheler Nathan M. , Tharp Ryan M. , Buckel Jeffrey A. 
Published: July 2022

Abstract
Descender devices are increasingly recognized as a leading means of barotrauma mitigation for released reef fishes. Yet, some resource users oppose regulations requiring or encouraging descender device use, arguing that predators frequently eat fish during release (depredation), sometimes causing device loss. We synthesized data for over 1,200 descended releases (both videoed and nonvideoed) of 16 species of reef fish off North Carolina, USA. Of 114 videos, we observed possible predators on seven, none of which showed actual depredation. Of 1,176 nonvideoed releases, we lost zero descender devices, indicating that although cryptic depredation may have occurred, equipment loss was nonexistent. The lack of any evidence of depredation in ocean waters off North Carolina provides information to managers that they can use to reinforce education and outreach to encourage descender use.
Analytical solution for the consolidation of unsaturated vertical drain foundation under depth‐dependent initial conditions
Authors: Zhou Tong , Li Tianyi , Wang Lei , Wen Minjie , Chen Yang 
Published: July 2022

AbstractInsufficient bearing capacity of foundations is hazardous for construction engineering, and improper construction scheme can also lead to unexpected problems. Vertical drains are always installed in the soil foundations to accelerate the consolidation process and thus improve the bearing capacity. According to the consolidation theory proposed by Fredlund, the consolidation of unsaturated vertical drain foundation is investigated with analytical solutions, in which smear effect, drain resistance, and depth‐dependent initial excess pore pressures (i.e., excess pore‐air and pore‐water pressures) are considered. In the derivative process, the decoupling method and Fourier series expansion method are applied. The reliability of the current solutions is verified by comparing the degenerate ones with existing solutions. Sensitivity analysis is conducted to assess the consolidation characteristics of the proposed model against modeling sizes, smear coefficients, drain resistance factors, and distribution coefficients. The analytical model has the advantages of simplicity and easy to implement in practical engineering.
Association for Social Anthropology in Oceania 2021 Conference Distinguished Lecture: Contemporary Filmmaking in Oceania
Authors: Ramones Ikaika , McCartney Marina Alofagia , Maden Martin 
Published: July 2022

ABSTRACTThis piece is an edited version of the Distinguished Lecture at the 2021 ASAO conference. The discussion centers the real life lessons and experiences of filmmakers, contributing to and challenging conversations about media and cultural production. The piece begins with a brief overview of the past and present of visual anthropology and media in Oceania. Panelists then recount their own journeys to filmmaking in their lives. The discussion moves to the industry and demographic concerns of film in the region, as well as questions of developing national identities and their experiences of production in different cultural contexts. Panelists speak in detail on the systemic barriers of accessing funding, and about film as a profession in the context of ethnic, gender, and class inequality. After speaking about the nature of transnational collaborations and relationships, panelists discuss the value of communities viewing themselves on screen, and the importance of accountability.
The gs3 allele from a large‐grain rice cultivar, Akita 63, increases yield and improves nitrogen‐use efficiency
Authors: Yoon Dong‐Kyung , Suganami Mao , Ishiyama Keiki , Kagawa Takaaki , Tanaka Marin , Nagao Rina , Takagi Daisuke , Ishida Hiroyuki , Suzuki Yuji , Mae Tadahiko , Makino Amane , Obara Mitsuhiro 
Published: July 2022

AbstractThe Green Revolution allowed a large amount of nitrogen (N) fertilization to increase crop yield but has led to severe environmental pollution. Therefore, increasing the crop grain yield must be achieved without such considerable input of N fertilization. A large‐grain japonica rice cultivar, Akita 63, significantly increased grain yield and improved N‐use efficiency (NUE) for yield per amount of N absorbed by plants. This study found that the nonsense mutated GS3 gene, the gs3 allele of Akita 63, has a superior yield production with enlarged grain size. The gs3 allele increased the yield with improvements in harvest index and NUE for yields per plant N content by analyzing the near‐isogenic line of rice plants with a large grain (LG‐Notohikari), which was developed by introducing the gs3 allele of Akita 63 into normal‐grain japonica cultivar, Notohikari. Thus, the gs3 allele would be promising for further yield increase without additional large input of N fertilization in non‐gs3‐allele rice varieties.
Identification of microRNAs and their target genes related to the accumulation of anthocyanin in purple potato tubers (Solanum tuberosum)
Authors: Wu Xiaojuan , Ma Yanhong , Wu Juan , Wang Peijie , Zhang Zhicheng , Xie Rui , Liu Jie , Fan Bobo , Wei Wei , Nie Li Zhen , Liu Xuting 
Published: July 2022

AbstractMicroRNAs (miRNAs) are types of endogenous non‐coding small RNAs found in eukaryotes that are 18–25 nucleotides long. miRNAs are considered to be key regulatory factors of the expression of target mRNA. The roles of miRNAs involved in the regulation of anthocyanin accumulation in pigmented potatoes have not been systematically reported. In this study, the differentially expressed miRNAs and their target genes involved in the accumulation of anthocyanin during different developmental stages in purple potato (Solanum tuberosum L.) were identified using small RNA (sRNA) and degradome sequencing. A total of 275 differentially expressed miRNAs were identified in the sRNA libraries. A total of 69,387,200 raw reads were obtained from three degradome libraries. The anthocyanin responsive miRNA–mRNA modules were analyzed, and 37 miRNAs and 23 target genes were obtained. Different miRNAs regulate the key enzymes of anthocyanin synthesis in purple potato. The structural genes included phenylalanine ammonia lyase, chalcone isomerase, flavanone 3‐hydroxylase, and anthocyanidin 3‐O‐glucosyltransferase. The regulatory genes included WD40, MYB, and SPL9. stu‐miR172e‐5p_L‐1R‐1, stu‐miR828a, stu‐miR29b‐4‐5p, stu‐miR8019‐5p_L‐4R‐3, stu‐miR396b‐5p, stu‐miR5303f_L‐7R + 2, stu‐miR7997a_L‐3, stu‐miR7997b_L‐3, stu‐miR7997c_L + 3R‐5_2ss2TA3AG, stu‐miR156f‐5p_L + 1, stu‐miR156a, stu‐miR156a_R‐1, stu‐miR156e, stu‐miR858, stu‐miR5021, stu‐miR828 and their target genes were validated by qRT‐PCR. They play important roles in the coloration and accumulation of purple potatoes. These results provide new insights into the biosynthesis of anthocyanins in pigmented potatoes.
A systematic review and meta‐analysis of the effect of thymol as an anti‐inflammatory and wound healing agent
Authors: Gabbai‐Armelin Paulo R. , Sales Luciana S. , Ferrisse Túlio Morandin , De Oliveira Analu Barros , De Oliveira Juliana R. , Giro Elisa M. A , Brighenti Fernanda L. 
Published: July 2022

AbstractThymol (THY) exhibits antibacterial and antioxidant properties. Recent studies have also shown that THY presents anti‐inflammatory and healing properties. This review focused on in vitro and in vivo investigations related to THY utilization, as an anti‐inflammatory and/or wound healing agent. PubMed, WebOfScience, and Scopus were examined. Independent reviewers conducted all diagram steps. PRISMA was followed for data extraction. RoB 2 and SYRCLE were utilized to assess the risk of bias for in vitro and animal studies. Meta‐analysis was performed for in vitro and in vivo articles that investigated THY as an anti‐inflammatory agent. Thirty‐six and 15 articles were included in the qualitative analysis and meta‐analysis, respectively. Studies showed high risk of bias related to sampling, allocation procedures, randomization, and blinding. Even so, for in vitro studies, significant result was observed for IL‐2. For in vivo studies, significant results were found for IL‐1, IL‐17, TNF‐α, AST, MPO, and CRP, with higher levels noticed in control groups. THY presents significant properties as anti‐inflammatory, ameliorating affections of the digestive system, cardiovascular problems, respiratory system and dermal damages, and burns. Researches are needed to clarify THY dose–response relationship and its mechanism of action, especially in the application of THY as a healing agent.
Desquamation of the subpleural lung parenchyma caused by empyema after pulmonary embolism: A case report
Authors: Iguchi Takafumi , Mizuguchi Shinjiro , Kyukwang Chung , Nakajima Ryu , Takahama Makoto 
Published: July 2022

Key messageSubpleural peripheral lung regions are mainly nourished by pulmonary arteries. Herein, we report a case in which pleural infection after pulmonary embolism caused circulation failure in the subpleural lung parenchyma (SLP) and massive desquamation of the SLP.
Correlation filters tissue tracking with application to robotic minimally invasive surgery
Authors: Sun Yanwen , Pan Bo , Fu Yili 
Published: July 2022

AbstractPurposeVision‐based tissue tracking is a significant component for building efficient autonomous surgical robot system. While the methodology involves various challenges caused by occlusion, deformation and appearance changes.MethodsWe propose a novel correlation filter tissue tracking framework for minimally invasive surgery. Our model contains the innovative design of synthetic features, a bi‐branch is exploited to enhance the response map. An incrementally learnt detector with the novel updating and trigger schemes is embedded to model the re‐detection module for capturing the lost target.ResultsPromising validation has been conducted on the publicly available tracking benchmark datasets, a surgical tissue tracking dataset based on publicly available Cholec80 dataset has also been developed to focus on the application in intra‐operative scenes.ConclusionsOur proposed framework meets the outstanding performance and surpasses the existing methods. The work demonstrates the feasibility to perform tissue tracking by taking advantage of the correlation filter.
Effect of Different Composition of Polyethylene Oxide‐Polypyrrole (PEO‐PPy) Nanofiber Mats on Antibacterial and Biocompatibility Properties
Authors: Masmur Indra , Perangin‐angin Sabarmin , Sembiring Helmina , Tarigan Afri Haganta , Ginting Junedi , Barus Diana Alemin , Ginting Mimpin 
Published: July 2022

AbstractElectrospun nanofibers are unique one‐dimensional materials with high surface area to volume ratio which can be used in various applications including in antibacterial application. In this study, we demonstrated a simple fabrication of polyethylene oxide‐polypyrrole (PEO‐PPy) composite nanofibers with antibacterial properties. The polymerization of pyrrole was conducted using ammonium persulfate (APS) initiator at ambient temperature for 24 h. The resulting PEO‐PPy nanofibers were then characterized by scanning electron microscopy (SEM), X‐ray diffraction (XRD), fourier transform infrared (FTIR), and tensile tests. The morphology of nanofibers observed by SEM revealed that the minimum concentration of PEO was 8 wt% to obtain the bead‐free nanofibers. Meanwhile, variation of pyrrole concentration does not alter the morphology of nanofibers significantly. The crystallinity of the nanofibers increased with increasing the PEO amount indicated by two typical peaks located at 2θ=19° and 23°, respectively. On the other hand, polypyrrole contributed the antibacterial properties significantly to the nanofibers and as a result, the antibacterial activity determined by UV‐Vis spectrophotometer increased dramatically with increasing pyrrole concentration from 0.1 to 0.2, 0.3, 0.4, and 0.5 mM. The electrospun nanofiber mats exhibited good antibacterial properties onE. coliand biocompatibility properties on L929 fibroblasts cell.
Biomedical Applications of Dendrimer Functionalized Magnetic Nanoparticles
Authors: Krishnan Raji Rama , Chandran Shine Rama , Johnson Elizabath , Hariharan Prema Kakkadath 
Published: July 2022

AbstractMagnetic nanoparticles (MNPs) have been identified as promising tools with potential use in a wide range of areas, spreading from diagnostics to the treatment of diseases. The high magnetization value and ability to pass cellular barriers promote them to be used as magnetic resonance imaging (MRI) agents, gene delivery agents, hyperthermia therapy, and for tissue repair. Use of functionalized MNPs with macromolecules minimizes their risks in biological systems and offers organ specific diagnosis and therapy. MNPs functionalized with dendrimers can have better potential in terms of enhanced stability and dispersibility in aqueous solution. The particular review summarizes the recent advances in synthesis of dendrimer functionalized MNPs and their applications in biomedical field such as targeted drug delivery, MRI, magnetic hyperthermia treatment and as antimicrobial agent.
Bis(imino)acenaphthene N‐Heterocyclic Carbene Palladium Complexes Bearing Tertiary Amines: Structural and Catalytic Studies on the Interaction between Soft Acid and Hard Base
Authors: Chen Ming‐Tsz , Hsu Mu , Lin Mei‐Chen , Lien Yu‐Cheng , Chen Kuan‐Wei 
Published: July 2022

AbstractThe HSAB principle in designing Bis(imino)acenaphthene N‐heterocyclic carbene (NHC) palladium complexes is presented. N‐donor ligands serve as hard bases to enhance the catalytic activities of NHC Pd complexes in Suzuki and Buchwald–Hartwig amination reactions. The Pd complex bearing tertiary amine ligands exhibited higher performance in coupling reactions than those exhibited by other soft base ligands reported in literature. 48 coupling products were generated in moderate‐to‐complete yields in the presence of aryl chlorides as substrates for Suzuki and amination reactions in air under mild conditions.