bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ferroptosis: a potential therapeutic target for Alzheimer’s disease
Authors: Yang Lan , Nao Jianfei 
Published: December 2022

Abstract
The most prevalent dementia-causing neurodegenerative condition is Alzheimer’s disease (AD). The aberrant buildup of amyloid β and tau hyperphosphorylation are the two most well-known theories about the mechanisms underlying AD development. However, a significant number of pharmacological clinical studies conducted around the world based on the two aforementioned theories have not shown promising outcomes, and AD is still not effectively treated. Ferroptosis, a non-apoptotic programmed cell death defined by the buildup of deadly amounts of iron-dependent lipid peroxides, has received more attention in recent years. A wealth of data is emerging to support the role of iron in the pathophysiology of AD. Cell line and animal studies applying ferroptosis modulators to the treatment of AD have shown encouraging results. Based on these studies, we describe in this review the underlying mechanisms of ferroptosis; the role that ferroptosis plays in AD pathology; and summarise some of the research advances in the treatment of AD with ferroptosis modulators. We hope to contribute to the clinical management of AD.
Kelvin–Helmholtz stability of rotating magnetoplasma with electron inertia
Authors: Pathan Tanveer A. , Sutar Devilal , Pensia Ram K. , Dashora Himani 
Published: December 2022

Abstract
In this theoretical exploration, the stabilizing or destabilizing impacts of the rotation, electron inertia, and electrical resistivity on the Kelvin–Helmholtz stability in two-superimposed incompressible magnetized plasma fluids incorporating finite ion Larmor radius (FLR) correction and suspended dust particulates are studied. The linearized perturbation equations for the Kelvin–Helmholtz instability problems are determined based on the magnetohydrodynamic (MHD) model. The general dispersion equation is derived by using appropriate boundary conditions. By the numerical estimation, the finite ion Larmor radius does not have any significant role in the Kelvin–Helmholtz instability of the magnetoplasma medium. The graphical estimates reveal the destabilization impact of the resistivity and electron inertia on the Kelvin–Helmholtz hydrodynamic plasma fluid system. In this paper, graphical representations have also analyzed the effect of rotation on the Kelvin–Helmholtz stability growth rate with the variation of electron inertia and resistivity. This current analysis provides pertinent information about the significant involvement of this considered system in space and astrophysical structures.
“Gangsta Chi”
Authors: Villegas Mark R 
Published: December 2022

This article sheds light on the pervasive yet largely uncommented upon presence of geek culture and Orientalism in hip hop, revealing the constructed, performed, and mediated nature of racialized masculinity in popular culture. By observing a range of media artifacts but concentrating on RZA’s memoir The Tao of the Wu (2009), this article contends that geeky hip hop Orientalism performs a strategy of style codeswitching, wherein the combination of intellectualism and the fantasized East expand the repertoire of Black masculinity and fantastical worldmaking. Heavy in Orientalist themes that mirror the hyper intellectualism associated with geekiness, The Tao of the Wu evinces the strong bond between geek culture and early hip hop music. Specifically, this article focuses on RZA’s mental cultivation over physicality and his enchantment by children’s media culture (comics, anime, and kung fu cinema).Merging hip hop and geek culture, which conventionally appear to exist on opposite poles, results in new interracial paradigms of geek and hip hop representations. Hip hop geekiness largely detours from an otherwise presumed whiteness in routing itself along a storied legacy of African American Orientalism. In this way, geeky hip hop Orientalism contributes to more queered and quotidian versions of Afro Asian aesthetics, politics, and interracial fantasy worlds. A deep consideration of the bonds among hip hop, geekiness, and Orientalism helps to reimagine the embodiments and performances of racialized masculinity, which, though complex and limited, can gesture towards the freedoms promised in a more expansive spectrum of gender and sexual affinities and identities.
Teaching with biosecurity content in the social sciences learning area: A Year 13 social science teacher’s experience
Authors: Ram Rajesh 
Published: December 2022

In this era of pandemics, asylum seekers, and conflict between super powers, social sciences are a critical subject that can help develop young people who can not only recognise racial and social discrimination but also injustices at a regional, national, and global scale.
Mainstream subjects, such as sociology, routinely support learning in the social sciences area. As a science/biology teacher, I wanted to find out whether biosecurity science could be used to support learning in the social sciences area. My interest in biosecurity stems from personal and professional experiences in New Zealand. Further, in my own pedagogical experience, teaching science/biology in schools, I found young people (15–18 years) were unfamiliar with the concept of biosecurity in New Zealand.
Considering my experiences, I set out to conduct research to look at the efficacy of using biosecurity in teaching and learning. This paper reports on the experience of one Year 13 social science teacher who used biosecurity content to teach in the social sciences learning area. Classroom observations and individual teacher interviews were used to gather data. The results show that biosecurity content engaged Year 13 social sciences students in the classroom and that the teacher used transformational learning theory to engage his students into undertaking social action related to biosecurity. Given the importance of biosecurity to New Zealand, this paper shows that social sciences as a learning area could support teaching and learning about biosecurity.
Lived Experience of Iranian Family Caregivers of Tubercular Patients: A Qualitative Study
Authors: Mohebbi Zinat , Dehbozorgi Raziye , Setoodeh Giti , Momennasab Marzieh , Heydari Naval , Shaygan Maryam 
Published: December 2022

Objective. To investigate the lived experience of family caregivers of persons with tuberculosis.
Methods. In this study, the method of hermeneutic phenomenology. Data were collected through online in-depth semi-structured interviews with nine family caregivers of TB patients. The obtained data were thematically analyzed to explain the concept of home care for TB patients through van Manen's 6-step methodology.
Results. After the thematic analysis, three main themes of caregivers'; mental distresses, quality care stasis, andfacilitated care were obtained from 944 primary codes and 11 categories.
Conclusion. Family caregivers of these patients suffer from mental distress. This issue affects the quality and ease of caregiving for these patients. Therefore, policymakers of this area should pay attention to the family caregivers of these patients and attempt to provide support; they should try to improve their quality of life.
Seismicity Scenarios for the Remaining Operating Period of the Gas Field in Groningen, Netherlands
Authors: Zöller Gert , Hainzl Sebastian 
Published: December 2022

AbstractIn recent years, induced seismicity at the Groningen gas field caused increasing public concern and became a critical factor for future gas production plans. Zöller and Holschneider (2016) estimated the upper bound of the 90% confidence interval for the maximum possible magnitude based on the earthquake catalog until 2016 and found M 4.4. In this study, we show that the updated estimate for earthquake activity until 2022 decreases to M 4.0. For the 95% confidence interval, the upper bound that was infinite for the catalog until 2016 decreases to the value M 4.2 for the updated catalog. Because the frequency–magnitude distribution is stable within the uncertainties, it is likely that the growth of the earthquake catalog since 2016 has led to decreasing uncertainties and thus to smaller confidence intervals. Second, we find that a model based on rate-and-state dependent friction with additional aftershocks fits the available data well. Despite the overall decreasing earthquake rate resulting from decreasing production volumes, scenario calculations based on simulated pressure and compaction data indicate a considerable probability that the maximum expected magnitude in the next 30 yr exceeds the maximum observed magnitude from the past 30 yr.
Crude Palm Oil Corruption: A Discourse on the Imposition of Capital Punishment
Authors: Camila Dwi , Syamsu Andi Pramudya , Firdaus Ayi Dudi , Norzulaika Siti , Binti Sulaiman Wan Nurainun Najwa 
Published: December 2022

The study aims to discuss on the corruption of Crude Palm Oil (CPO) export cases that have led to the scarcity of cooking oil at affordable prices in Indonesia. It is harmful for the public as the Crude Palm Oil (CPO) has been exported without a permit and does not meet the requirements of Domestic Market Obligation (DMO) and Domestic Price Obligation (DPO). The study is a normative legal research employing descriptive-qualitative upon data collected through a library study. The study shows that the case of crude palm oil (CPO) export corruption made the supply of cooking oil disrupted that led to economic and political instability. In response to this, the government conducted an investigation and found several suspects of corruption cases. While the legal process running, the discourse on the application of death penalty arose within the society. It was so because this corruption occurred during the pandemic. However, the use of the capital punishment in cases of corruption is restricted because it can only be used in specified circumstances, especially when the funds are intended for dealing with dangerous situations, national natural disasters, social unrest, economic and monetary problems, and corruption repetition.
Clinical dielema-epithelial myoepithelial carcinoma- rare presentation
Authors: Venkitaraman Lakshmi , Kumari Anitha , Paulson Smitha 
Published: December 2022

To describe our experience with a case of epithelial myoepithelial carcinoma that was reported as two different entities and thus proved to be a challenging case.: Retrospective review of histo-pathological reports with detailed work up of final findings and treatment. Four year follow up of the patient shows successful treatment with no recurrence. High index of suspicion and detailed histo-pathological evaluation with IHC testing is needed in tumours presenting with mixed cell population.
Synchronous endometrioid carcinoma of endometrium and ovary: A case report
Authors: Lavanya V. , Dhanalakshmi S 
Published: December 2022

The synchronous endometrial and ovarian cancer is a rare phenomenon with incidence of 1.4 to 3.8%. Mostly in SEOC, the ovarian endometroid carcinoma arises in background of endometriosis with endometrial carcinoma with lower stage and lower grade in premenopausal age group.Herein we present a case of 33year old female, presented with abdominal pain, underwent TAH with BSO and histopathologically uterus and ovary showing features of Synchronous endometrial and ovarian carcinoma of low grade with no nodal involvemnet in premenopausal lady.The SEOC being a rare phenomenon with different therapeutic and favorable prognostic considerations, when compared with metastatic carcinomas and hence SEOC can be managed with multidisciplinary approach and regular follow up.
POR UMA EDUCAÇÃO FORA DO ARMÁRIO:
Authors: Flores Bruno , Guedes Pacheco Eduardo 
Published: December 2022

O texto aqui apresentado compõe o conjunto de trabalhos do Grupo de Pesquisa CAPES Zona de Investigações Poéticas - ZIP e do Programa de Pós-Graduação em Educação - Mestrado Profissional da UERGS, sendo parte da proposta de dissertação intitulada “ESQUIZOESCOLA: Experiências de corpos desejantes por outras educações”. Este artigo tem a intenção de discutir sobre as questões de gênero, sexo e sexualidade e como estes entendimentos são atravessados pelas perspectivas propostas pela binariedade. Para tanto, o trabalho busca problematizar cada um destes termos apresentando entendimentos mais amplos do que aqueles tratados pelos dualistas. A realização deste movimento acontece acompanhado de referências como Rudião Rafael Wisniewski, Guacira Lopes Louro, Denise da Silva Braga, entre outras, e algumas falas de manifestos LGBTQIAP+. O texto, junto a problematização desses conceitos, apresenta um recorte histórico sobre a construção do movimento LGBTQIAP+ e da cisheteronormatividade.
Berita Pustaka as historical source of Bandung Institute of Technology Library in 1970’s
Authors: Supratman Frial Ramadhan 
Published: December 2022

Background of the Study: History of Indonesian library is less explored field in library studies. Debates on history of Indonesian library seems to be unexplored due to pressure on librarian to adapt with technological changes. It causes development of history of Indonesian library seems stagnant among scholars of library science and librarians. Meanwhile, in the field of history itself, library history is less attractive for historians. The development of historiography since 1980’s is more concerned with social movement history, though library played significant role in the field of education and research in Indonesia. Almost all research centers and universities certainly need library for obtaining references.
Purpose: This article observes one of National Library of Indonesia’s rare collection named Berita Pustaka. The collection is a tabloid published by Center Library of Bandung Institute of Technology (ITB) in 1970’s. Today the collection is still deposited in Rare Newspaper Division, National Library of Indonesia with call number QQ-131.
Method: In this article author uses qualitative method along with deep analysis of Berita Pustaka. Therefore, author also uses historical approach as a methodology in this article.
Finding: In addition, the collection also contains information regarding library service for faculty members and students in 1970’s.
Conclusion: Author argues that Berita Pustaka is an information source for researching history of Indonesian library, particularly higher education library.
A tale of three fluids: Fluid-inclusion and carbonate clumped-isotope paleothermometry reveals complex dolomitization and dedolomitization history of the Latemar platform
Authors: Mueller Mathias , Walter Benjamin F. , Swart Peter K. , Jöns Niels , Jacquemyn Carl , Igbokwe Onyedika A. , Immenhauser Adrian 
Published: December 2022

Abstract
This work focuses on an exceptionally complex natural laboratory, the Triassic Latemar isolated platform in the Dolomite Mountains of northern Italy. It explores spatial and temporal gradients in processes and products related to contact metamorphism, dolomitization, and the dedolomitization of marine limestones. Rock samples were studied using dual fluid-inclusion thermometry and clumped-isotope thermometry. Independent of the spatial position at Latemar, Δ47 clumped-isotope and fluid-inclusion data provide contrasting paleotemperature estimates. An apparent lack of systematic patterns in fluid-inclusion data (homogenization temperature, salinity, density) results from analyses of micrometer-sized growth zones within a single crystal. The composition of the individual fluid inclusions represents a “snapshot” of fluid mixing with variable endmember elemental ratios. The bulk crush-leach data and slopes in Caexcessversus Nadeficit diagrams indicate different water–rock interactions and fluid signatures with evaporation sequences and crystalline rocks. The presence of three fluid types (crystalline basement brine, halite-dissolution brine, seawater) in all carbonates suggests that all fluids coexisted during contact metamorphism and dolomitization of Latemar carbonates. Non-equilibrium processes overruled thermodynamic controls on the precipitation of diagenetic phases. Fluid mixing resulted in the precipitation of two complex carbonate successions. The Δ47 data represent bulk temperatures, averaging the mixing ratio of fluids with different temperatures and their respective volume. Fluid-inclusions record patterns of remarkable complexity and shed light on the complexity of a multi-fluid system. Data shown here provide answers to the controversial interpretation of dolomitizing fluid temperature in the Latemar and exemplify the strengths of multi-proxy paleotemperature studies.
LGBTQIA+ cartographies in filmic Madrid: narrative traits of spatial characterization
Authors: Álfeo Juan Carlos , Deltell Escolar Luis 
Published: December 2022

Cartografías cinematográficas LGBTQIA+ en el Madrid fílmico: rasgos narrativos de caracterización espacial
En este trabajo se analiza el repertorio espacial y sus rasgos dominantes como fuente de caracterización indirecta de los personajes LGTBQI+, estudiando su representación en largometrajes de ficción localizados en Madrid y su provincia y exhibidos en el circuito comercial. La metodología que sirve de base al estudio es de tipo cualitativo, fundamentalmente, y es un desarrollo propio de los autores inspirado en el análisis de marcas narrativas de Hamon, concepto redefinido, a su vez, por Chatman como rasgo narrativo y en el estudio de los espacios diferenciales y los modelos de Casetti y di Chio. El objetivo fundamental es el de precisar, en suma, qué espacios componen el universo narrativo LGTBQI+, es decir, la cartografía cinematográfica que el cine elabora y propone para cada grupo de personajes en la Comunidad de Madrid y, ya que se ha constatado que no todos ellos han recibido el mismo tratamiento ni han sido representados con el mismo detalle y extensión, cuáles son sus rasgos diferenciales.
Pemanfaatan Limbah Kulit Jeruk sebagai Fortifikan Guna Memperkaya Nilai Gizi pada Cokelat
Authors: Mustafidah Roufi'ul , Asyari Rizki Putri , Velayati Jihan Maghfiroh , Sayekti Titah 
Published: December 2022

Jeruk merupakan salah satu komoditas buah-buahan yang memiliki banyak manfaat bagi kesehatan manusia. Kecamatan Pulung merupakan penghasil jeruk keprok Pulung yang menjadi salah satu komoditas unggul di daerah Ponorogo. Namun, pemanfaatan jeruk hanya bagian daging buahnya saja sedangkan bagian kulitnya dibuang. Kulit jeruk yang dianggap sebagai limbah ternyata dapat dikonsumsi dan memiliki berbagai kandungan seperti antioksidan dan mineral seperti kalsium, selenium, mangan, seng, dan vitamin (C, A, B-kompleks) beberapa kali lipat dari pulpnya. Adanya berbagai kandungan tersebut menjadikan kulit jeruk layak dimanfaatkan menjadi berbagai macam olahan pangan yang variatif, lezat, dan bermanfaat bagi kesehatan. Salah satu camilan yang digemari semua kalangan adalah cokelat. Penelitian ini bertujuan untuk membuat cokelat kulit jeruk sebagai camilan yang memiliki nilai gizi. Penelitian ini menggunakan metode deskriptif kuantitatif. Data didapatkan dari hasil uji kandungan gizi dan berbagai referensi yang berkaitan dengan permasalahan yang dibahas. Hasil penelitian ini menunjukkan bahwa dalam Cokelat Kulit Jeruk (CULUK) berpotensi untuk diproduksi sebagai salah satu alternatif camilan yang lezat dan sehat yang memiliki kandungan protein, lemak dan karbohidrat. Selain itu, 100 gram CULUK mengandung 29.24% antioksidan dan 13.37% vitamin C. Dengan demikian, fortifikasi kulit jeruk dalam pembuatan cokelat dapat meningkatkan nilai guna kulit jeruk dan sekaligus menambah nilai gizi dari olahan cokelat itu sendiri.
Terampil Membuat Kesimpulan Melalui Model Inkuiri Berbasis Science Education for Sustainable Development
Authors: Hani'ah Roudhotul , Fadly Wirawan 
Published: December 2022

Perkembangan dalam ranah pendidikan saat ini lebih menuntut peserta didik untuk berperan aktif. Keterampilan proses siswa berperan penting dalam hal ini, salah satunya yaitu keterampilan menyimpulkan. Tujuan penelitian ini yaitu untuk mengetahui apakah model inkuiri dengan pendekatan SESD lebih efektif dari pada model konvensional dalam meningkatkan kemampuan membuat kesimpulan peserta didik. Metode yang digunakan dalam penelitian ini yaitu kuantitatif true experimental dengan desain pretest- posttestcontrol group desaign. Sampel dalam penelitian ini yaitu peserta didik MTs Darul Huda kelas VII T (eksperimen) berjumlah 31 orang dan kelas VII Z2 (kontrol) berjumlah 28 orang. Adapun analisis data menggunakan deskriptif kuantitatif, serta pengumpulan data yakni berupa observasi dan soal tes. Hasil penelitian menjunjukkanbahwa indikator membuat kesimpulan dengan pencapaian tertinggi yaitu membuat kesimpulan secara deduktif dengan nilai N- gain 0,71 termasuk kategori tinggi. Sedangkan membuat kesimpulan secara induktif menjadi indikator dengan ketercapaian terendah dengan nilai N- gain 0,46 termasuk kategori sedang. Dari hasil analisis data, dapat disimpulkan model inkuri dengan pendekatan SESD lebih efektif dalam meningkatkan kemampuan membuat kesimpulan peserta didik.
Community-based Zigzag Piloting Algorithm for the Strong Generalized Minimum Label Spanning Tree Problem
Authors: LONG Hao , Li Xiao-xia , LONG Zhu-ming , Wu Fu-ying 
Published: December 2022

Abstract
Edge-labeled graph (ELG) is an important abstract model of many practical applications, in which each edge is associated with one or more labels. Searching the minimum label spanning tree (MLST) of ELG is an important issue and proved NP-hard. In the last decade, researchers have put forward some algorithms, however, high computational cost and lower searching effectiveness are still the main obstacles, especially for large-size graphs. In this paper, we propose a heuristic to solve the strong generalized MLST problem (SGMLSTP). We decompose the SGMLSTP into two sub-problems, one is to search a sub-graph containing one or more spanning trees with the minimum labels from the original graph, and another is to search a spanning tree from the acquired sub-graph. As the latter sub-problem is already solved effectively, we focus on the former sub-problem and propose a community-based zigzag piloting algorithm: Firstly a weighted label graph is derived from the edge-labeled graph; then the label graph is partitioned and label communities are chosen in combination to form the initial solutions; finally, the zigzag piloting process is applied to make the initial solutions feasible and refined, of which the optimum one has the least labels. Label partition largely reduces the computation cost of searching the initial solutions, the zigzag piloting process help increase searching effectiveness, and experimental results on typical benchmark datasets fully verify this point and show better effectiveness and performance than that of the state-of-the-art algorithms.