bluuebunny/crossref_metadata_2025_split huggingface dataset:
Catechins in cancer therapy: integrating traditional and complementary approaches
Authors: Dwivedi Renu , Bala Rajni , Singh Sumitra , Sindhu Rakesh K. 
Published: February 2025

Abstract
Catechin is a group of bioactive flavonoids found in various plant sources such as tea, cocoa, and fruits. Recent studies have suggested that catechins has significant potential in preventing and treating cancer. Catechin exhibits a variety of biological activities that may contribute to its anticancer effects, including antioxidant, anti-inflammatory, and pro-apoptotic properties. Studies have demonstrated that catechin can inhibit cancer cell proliferation, induce cell cycle arrest, and promote apoptosis across multiple cancer types, including skin, breast, lung, liver, prostate, and colon cancers. Furthermore, catechin has shown the ability to inhibit angiogenesis, a critical process for tumor growth and metastasis, by restricting new blood vessel formation. Catechin’s impact on cancer extends beyond its direct effects on cancer cells. It modulates various signaling pathways involved in cancer progression, such as those associated with cell survival, inflammation, and metastasis. Despite these promising findings, additional research is needed to clarify the precise mechanisms of catechin’s anticancer action, optimal dosing strategies, and long-term safety in cancer prevention and treatment. This review will explore the current research landscape on tea polyphenols, particularly catechin, and their potential role in cancer prevention and therapy.
A character theoretic criterion for Fitting height
Authors: Lv Heng , Deng Yuqi , Yang Yong 
Published: February 2025

Abstract
For a finite group 𝐺, set

Irr
N

⁡

(
G
)

:=

{
χ
∈
Irr

(
G
)

∣
χ

(
1
)

2

∤

|
G
:
ker
χ
|

}

,

cd
N

⁡

(
G
)

:=

{

χ
⁢

(
1
)

∣

χ
∈

Irr
N

⁡

(
G
)

}

.

\begin{aligned} \operatorname{Irr}_{N}(G)&:=\{\chi\in\operatorname{Irr}(G)\mid\chi{(1)^{2}}\nmid\lvert G:\operatorname{ker}\chi\rvert\},\\
\operatorname{cd}_{N}(G)&:=\{\chi(1)\mid\chi\in\operatorname{Irr}_{N}(G)\}.\end{aligned}

In this paper, we study finite groups 𝐺 with

|

cd
N

⁡

(
G
)

|

≤
1

\lvert\operatorname{cd}_{N}(G)\rvert\leq 1

.
In particular, we prove that if 𝐺 has odd order, then

h
⁢

(
G
)

≤

|

cd
N

⁡

(
G
)

|

+
1

h(G)\leq\lvert\operatorname{cd}_{N}(G)\rvert+1

, where

h
⁢

(
G
)

h(G)

is the Fitting height of 𝐺.
ИССЛЕДОВАНИЕ ТЕПЛОВОГО ВЗРЫВА В ПОРОШКОВОЙ СМЕСИ АЛЮМИНИЯ С НИКЕЛЕМ, ПРЕДВАРИТЕЛЬНО АКТИВИРОВАННЫМ В НИЗКОЭНЕРГЕТИЧЕСКОЙ ЛАБОРАТОРНОЙ МЕЛЬНИЦЕ
Authors: БОЯНГИН Е.Н. , ЛАПШИН О.В. 
Published: February 2025

В работе изучено влияние предварительной низкоэнергетической механической активации (НМА) порошка никеля на тепловой взрыв интерметаллида Ni3Al. Рассмотрены два способа синтеза. В первом осуществлялся непрерывный нагрев смеси внешним источником энергии. Во втором при достижении заданной температуры внешний источник отключался. Показано, что НМА никеля способствует интенсификации синтеза интерметаллида Ni3Al. При непрерывном нагреве температура воспламенения не зависит от времени НМА и равна температуре плавления алюминия. При нагреве с отключением внешнего источника предварительная активация никеля снижает температуру твердофазного воспламенения. Установлено, что активация никеля в лабораторной мельнице позволяет избежать факторов его пассивации.
The effect of preliminary low-energy mechanical activation (MA) of nickel powder on the thermal explosion of the Ni3Al intermetallic compound has been studied. Two synthesis methods are considered. In the first, the mixture was continuously heated by an external energy source. In the second, when the set temperature was reached, the external source was turned off. It has been shown that low-energy MA of nickel promotes the intensification of the synthesis of the Ni3Al intermetallic compound. With continuous heating, the ignition temperature does not depend on the activation time and is equal to the melting point of aluminum. When heating with the external source turned off, preliminary activation of nickel reduces the solid-phase ignition temperature. It has been established that the activation of nickel in a laboratory mill allows one to avoid the factors of its passivation.
ДВУХУРОВНЕВЫЕ МОДЕЛИ СИНТЕЗА КОМПОЗИТОВ: ИСТОРИЯ И ВОЗМОЖНОСТИ
Authors: КНЯЗЕВА А Г. 
Published: February 2025

Существуют разнообразные способы синтеза композитов из смесей порошков металлов, формирующих интерметаллидные фазы, а также из смесей порошков металлов и неметаллов (например, углерода или бора). В 70-е годы прошлого столетия был предложен подход к описанию процессов горения и взрыва с выделением реакционных ячеек, который с современных позиций можно отнести к двухуровневым моделям синтеза. Подход активно развивался для бинарных систем, однако так и остался достаточно условным. В настоящей работе представлен обзор подобных моделей; предложено их развитие за счет учета сопутствующих процессов (не только диффузии, но и эволюции напряженно-деформированного состояния) и модификации применительно к синтезу, управляемому лазерным или электронным лучом.
There are various methods for synthesizing composites from mixtures of powders of metals forming intermetallic phases, as well as from mixtures of powders of metals and non-metals (for example, carbon or boron). In the 1970s, an approach was proposed to describe combustion and explosion processes with identification of reaction cells, which from modern positions can be classified with two-level synthesis models. The approach has been actively developed for binary systems, but remained rather conditional. This paper presents an overview of similar models; it is suggested that they can be developed by taking into account accompanying processes (not only diffusion, but also the evolution of the stress-strain state), and modified in relation to synthesis controlled by a laser or electron beam.
СИНТЕЗ ОКСИНИТРИДНЫХ КОМПОЗИТОВ ПРИ ГОРЕНИИ СМЕСИ ФЕРРОСИЛИЦИЙ‒ПРИРОДНЫЙ МИНЕРАЛ‒АЛЮМИНИЙ В АЗОТЕ
Authors: КРЮКОВА О.Г. , НЕВМЫВАКА А.А. , АКУЛИНКИН А.А. , ТАТАРИНОВА Т.В. 
Published: February 2025

Реализован направленный синтез оксинитридных композитов путем организации сопряженных процессов. В качестве основного (индуцирующего) процесса рассматривается взаимодействие ферросилиция в азоте в режиме горения. Фазовый состав продуктов сопряженных процессов определяется химическим и фазовым составом компонентов, добавляемых к ферросилицию перед проведением самораспространяющегося высокотемпературного синтеза. Установлено влияние основных параметров синтеза на скорость горения, содержание азота, фазовый состав и морфологию продуктов синтеза. Показана химическая стадийность взаимодействия ферросилиция с добавками природных минералов (циркон, ильменит, шунгит) и алюминия в атмосфере азота. Фазовый состав продуктов определяется химическими превращениями, происходящими в волне горения. Установлено, что введение алюминия способствует снижению либо устранению фазы Si2N2O в продуктах синтеза по мере его увеличения и получению композитов на основе твердого раствора Si3N4 (SiAlON). Микроструктура продуктов горения представлена сростками (5‒10 мкм) мелких ограненных кристаллов, бесформенными образованиями и пластинчатыми кристаллами. Получены оксинитридные композиты с открытой пористостью 51,0‒68,8 %.
Targeted synthesis of oxynitride composites is implemented by means of organizing coupled processes. Interaction of ferrosilicon with nitrogen in the combustion regime is considered as the main (inducing) process. The phase composition of the products of the coupled processes is determined by the chemical and phase compositions of the components added to ferrosilicon before performing self-propagating high-temperature synthesis. The influence of the basic products of the synthesis on the burning rate, fraction of nitrogen, phase composition, and morphology of synthesis products is considered. Chemical stages of ferrosilicon interaction with additives of natural minerals (zircon, ilmenite, and shungite) and aluminum in a nitrogen medium are demonstrated. The phase composition is determined by chemical transformations in the combustion wave. It is found that addition of aluminum leads to reduction or elimination of the Si2N2O phase in synthesis products with an increase in the aluminum fraction and obtaining composites based on the Si3N4 (SiAlON) solid solution. The microstructure of combustion products is presented by aggregates (5–10 μm) composed of small faceted crystals, shapeless structures, and crystal flakes. Oxynitride composites with an open porosity value of 51.0–68.8% are obtained.
Patient-specific Predictors of Haemolysis with Percutaneous Ventricular Assist Devices
Authors: Sullivan Alexander E , Granger Hannah , Dupuis Leonie , Napper Jonathan , Tran Lena , Laws J Lukas , Wells Quinn S , Farber-Eger Eric , Alvis Bret D , O’Leary Jared M , Bommareddi Swaroop , Amancherla Kaushik V , Rali Aniket S 
Published: February 2025

Introduction: Percutaneous ventricular assist devices (pVADs) are increasingly used in cardiogenic shock but are associated with complications including haemolysis. The aim of this study was to investigate patient characteristics associated with haemolysis in cardiogenic shock patient population. Methods: Consecutive patients were identified using Current Procedural Terminology (CPT) codes for pVAD insertion. Patient characteristics, laboratory and imaging data, and patient outcomes were abstracted manually and using validated automated methods. Laboratory-defined haemolysis required a drop in haemoglobin ≥2 mg/dl with either lactate dehydrogenase ≥250 units/l or undetectable haptoglobin. Clinically significant haemolysis was defined as laboratory-defined haemolysis necessitating transfusion. Primary outcome was the association between haemolysis and on-device and 30-day mortality. Results: A total of 196 patients underwent pVAD insertion for cardiogenic shock during the study period and were included. Laboratory-defined haemolysis occurred in 46 patients (23.5%), of whom 12 (6.1%) had clinically significant haemolysis. Haemolysis occurred more often following emergency insertion, rather than elective insertion (84.8% versus 40.0%, p<0.001) in patients with elevated lactic acid levels (median 2.5 versus 1.6, p=0.016) and elevated heart rates (92.5 BPM versus 86.5 BPM, p=0.023). After multivariable adjustment, there was no association between laboratory-defined haemolysis and on-device (OR 0.6; 95% CI [0.1–3.4]; p=0.565) or 30-day mortality (OR 2.1; 95% CI [0.4–13.0]; p=0.391). Conclusion: Laboratory-defined haemolysis was common in patients with cardiogenic shock and pVAD, but clinically significant haemolysis was not. There was no association between haemolysis and on-device or 30-day mortality.
МЕТОД РОЗВ’ЯЗАННЯ НЕСТАЦІОНАРНИХ ЗАДАЧ ТЕОРІЇ ТЕРМОПЛАСТИЧНОСТІ ДЛЯ ПЛАСТИН ТА ОБОЛОНОК
Authors: Стеблянко П. О. 
Published: February 2025

Існуючі дослідження в галузі теорії пластин та оболонок можна виокремити у два напрями: перший напрям – комбіновані аналітичні та напіваналітичні методи, які ґрунтуються на континуальній моделі розрахунку, та другий напрям, який базується на дискретному поданні розрахункової моделі, з метою використання добре відомих числових методів. Обидва напрями мають в своєму арсеналі потужні програмні комплекси, проте при практичній реалізації існуючих методів для складних оболонкових конструкцій виникає потреба покращувати отримані результати. Одна з можливостей базується на ідеї кардинального підвищення точності обчислень.
Occupational therapy services and perception of integration of these at primary healthcare level in South Africa
Authors: Jejelaye Anthony , Maseko Lebogang , Franzsen Denise 
Published: February 2025

Background: Literature indicates that access to rehabilitation services in South Africa is limited. Recent policy documents by the National Department of Health related to disability and rehabilitation propose the integration of occupational therapy services in primary healthcare (PHC). However, the implementation strategies concerning integration are not clear as there is inadequate evidence locally on the occupational therapy service provision in PHC even though there is growing evidence internationally.Purpose: This study sought to determine the services provided by occupational therapists in PHC and to explore the perceptions of the occupational therapists on the integration of occupational therapy services within the PHC reengineering streams of the National Insurance (NHI).Method: A two-phase explanatory sequential mixed method strategy was utilised in this study. A quantitative survey was sent to members of the occupational therapy professional association and an organisation of professionals providing rehabilitation services in rural communities. Qualitative data were then collected using semi-structured interviews with five therapists who completed the survey.Findings: Findings from this study showed there is increasing alignment of occupational therapy services in PHC with the community-based rehabilitation (CBR), the Social Model, the International Classification of Functioning, Disability and Health (ICF) and the Medical Model using client self-management and case-management intervention approaches. The majority of occupational therapists are currently based in district hospitals (42%), community health centres (16%), community organisations (8%), and clinics (8%).Those working in the community indicated they work in a multidisciplinary team (MDT). They also use PHC service delivery models to manage people with disabilities (PWDs). Occupational therapists in PHC have a strong perception of their relevance in the PHC reengineering streams, despite the numerous barriers and few facilitators to the integration of occupational therapy services in the PHC reengineering streams of the NHI.Conclusion: The perception of the study participants is that occupational therapy service integration in the PHC reengineeringstreams will lead to improved healthcare. However, they are also of the opinion that integration will not happen without advocacy from occupational therapists or occupational therapy being adequately supported in PHC.
Key words: Occupational therapy, primary health care re-engineering, integration, National Health Insurance, universal health coverage.
Chemical elements in the «soil – plants» system of floodplain landscapes in the city of Krasnoyarsk
Authors: Orban E.  S. , Sharafutdinov R.  A. 
Published: February 2025

Aim. Identification of the distribution of chemical elements in the system «soil–plants» floodplain landscapes of the large industrial city of Krasnoyarsk.Procedure and methods. In soil and plant samples by inductively coupled plasma atomic emission spectral analysis, the total content of chemical elements was determined. For the results obtained the accumulation coefficient showing the nature of the internal redistribution of chemical elements in the system «soil–plant» was calculated, a series of biological accumulation for 12 sites located within the low floodplain of the Yenisei River in Krasnoyarsk was compiled.Results. A ecological-geochemical analysis of the floodplain landscapes of the city of Krasnoyarsk was carried out. The basic regularities of the distribution of chemical elements in vegetation and soil cover are determined, the contribution of exogenous elements is estimated. Hyperaccumulation of Hg, Mn, Mo, S, Se, Zn by representatives of the genus Salix was revealed. It is noted that S makes the most significant contribution to the pollution of soils and vegetation of floodplain landscapes.Research implications. Significance of the study lies in identifying the quantitative ratio of chemical elements determining the level of technogenic load and stability of ecosystems functioning. The findings reflect the importance of preservation and role of floodplain landscapes in urban environment. The information obtained is also valuable for making possible management decisions when planning economic activities within the floodplain landscapes of an urbanized territory.
Scientific and methodological aspects of teaching courses on geoecological problems of plains and mountains areas in the permafrost zone
Authors: Zotova L. I. , Vikulina M. A. 
Published: February 2025

Aim. To reveal scientific and methodological techniques for creating and teaching geoecological disciplines in bachelor's and master's programs based on long-term methodological developments of Cryolithology and Glaciology Department of the Faculty of Geography of Lomonosov Moscow State University.Methodology. The author's methodology for studying, assessing and mapping the permafrostecological state of flat and mountainous permafrost areas is presented, based on landscape methods: landscape-indicative and landscape-structural. The advantages and disadvantages of the method of point expert assessments and one of the techniques for their improvement are shown. The conceptual provisions of the stability of cryogenic and high-mountain geosystems to mechanical disturbances of the surface are presented. The main assessment factors of avalanche danger and risk for recreational facilities in the mountains are listed.Results. The concepts of "geoecology of the cryolithozone", "stability of northern geosystems", "crisis geoecological situation" necessary for the geosystem approach to geoecological problems are formulated. The factors of cryogenic processes activation at different mapping scales and hazard & risk factors for high mountain areas are analyzed. A graphic-analytical method for comparing factor scores against the background of an interval scale in “quality centers” is shown. Examples of original practical tasks are demonstrated. The procedure for the integrated assessment of the lithocryogenic stability factors of landscapes to the manifestation of undesirable cryogenic processes is disclosed along with the factors of their bioresource value in order to obtain quantitative indices for ranking landscapes according to the degree of vulnerability to development. A number of significant permafrost maps compiled on a landscape basis are listed. Examples of original practical tasks are demonstrated.Research implications. The multifactor integral assessment methodology is in demand in engineering-geographical research, particularly during pre-project stages of land development, ensuring the reliable operation of engineering structures in the cryolithozone while maximizing environmental preservation. The methodological techniques are of practical interest for training specialists in natural sciences on environmental studies of the cryolithozone and mountainous regions.
Contemporary changes in regional specialisation of farming in PRC (1990–2018)
Authors: Naumov A. S. , Chubarov I. G. , Dvoretskiy V. A. 
Published: February 2025

Aim. Identifying the changes and factors in the allocation of China's major farming industries by analyzing statistical data for PRC provinces from 1990 to 2018.Methodology. The analysis of data on the dynamics of the territorial concentration of agriculture is based on the calculation of the index of localization of sown areas of crops by provinces, autonomous regions and cities of central subordination. The dynamics of the sown area of China's main agricultural crops in 1990-2018 was analyzed: rice, wheat, corn, soybeans, rapeseed, peanuts, sunflower, sugar cane, sugar beet, tobacco and tea, as well as aggregated data on root and tubers, other vegetable and fruit crops.Results. The analysis showed that the regions in the north and south-east of China differ in narrower specialization. In the whole country, the production of fruits, vegetables, cereals and peanuts was characterized by the lowest level of territorial concentration.Research implications. The results of the study allow us to conclude that China is increasingly integrating into the global system of agricultural areas, while these changes in the location of the main branches of agriculture significantly affect the transformation of the entire global system. Changes in the specialization of PRC farming at the national and regional levels can in positive and negative ways effect China’s import of Russian agricultural products.
Tourism development of the Mediterranean city of Mersin (Turkey): local’s opinion
Authors: Kondrateva S. V. 
Published: February 2025

Aim. This study seeks to identify both the opportunities and challenges for tourism development in the Mediterranean city of Mersin based on opinion of local residents.1Methodology. The study is based on data of two sociological surveys, various literature sources, and the author’s own observations. The opinion of local residents is evaluated through two sociological surveys conducted among Turkish citizens and the Russian-speaking residents of the city of Mersin from December 18, 2022, to February 5, 2023, and from April 4, 2023, to July 16, 2023. The empirical data consists of 245 anonymous questionnaires: 143 were completed by Turkish citizens in Turkish, and 102 by Russian-speaking people in Russian.Results. The findings indicate a generally positive view among locals regarding the prospects for tourism development in Mersin. Key potential benefits identified from tourism development include the creation of new jobs for locals (53.5% of respondents), enhancement of the city of Mersin's image (46.5%), and improvement of services available to both tourists and residents (46.5%). Despite this shared optimism, notable differences in opinions were observed between the Turkish citizens and the Russian-speaking community. The study revealed five main obstacles for tourism development in the city: infrastructural (underdeveloped tourism infrastructure), environmental (sea and beach pollution (especially with plastic); litter on the streets), economic (inflation; underinvestment of tourism; lack of a tourism development strategy), socio-cultural (language barrier, both Russian and English) aspects as well as legal challenges (changes in legislation, e.g., in requirements for getting a temporary residence permit for foreign citizens).Research implications. The outcomes of this study offer valuable insights into the preferences of the Russian-speaking tourists and the factors impeding tourism growth in Mersin. These findings may assist in boosting both the inbound tourist flow and the local tourism market. Additionally, the results may be applicable to other tourist destinations aiming to enhance or maintain tourist traffic from Russian-speaking countries.