bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tannic Acid Modified Single‐Walled Carbon Nanotube/Zinc Oxide Nanoparticle Thin Films for UV/Visible Semitransparent Photodiode‐Type Photodetectors
Authors: Lou Tian‐Jiao , Wang Jing‐Qi , Wang Wenyi , Wang Tao , Qian Peng‐Fei , Bao Ze‐Long , Jing Li‐Chao , Yuan Xiao‐Tong , Geng Hong‐Zhang 
Published: January 2022

AbstractFlexible electronic devices have received significant attention in recent years as a result of their flexibility and portability. Carbon nanotube (CNT) films could serve as a promising material for photodetection because of their broad absorption spectral coverage. In this research, vertical ultraviolet (UV) to visible (UV/Vis) detectors based on tannic acid functionalized carbon nanotube/zinc oxide (TCNT/ZnO) heterojunctions were prepared by a simple spraying method. The TCNT electrode had excellent photoelectric properties with a sheet resistance of 40.6 Ω/sq and transmittance of 80.4 % at 550 nm, and the resulting TCNT/ZnO device could achieve photocurrent of 3.0 mA at 360 nm in the UV range, a recession time of 8.05 s, photoresponsivity of 7.12 A/W, and detectivity of 25.2×1011 Jones. As a comparison, for the pure CNT electrode with a sheet resistance of 45.5 Ω/sq and transmittance of 79.6 % at 550 nm, the CNT/ZnO photocurrent was only 0.6 mA at 360 nm, with a recession time of 17.25 s, photoresponsivity of 1.00 A/W, and detectivity of 3.4×1011 Jones. The prepared device was also able to operate stably after 1000 mechanical bending tests and maintained more than 95 % detectivity, providing a feasible path for the generation of carbon nanotube based photodetector devices.
Influencing responsible green innovation in Dominican agribusiness performance
Authors: Ureña Espaillat Hayrold José , Briones Peñalver Antonio Juan , Bernal Conesa Juan Andrés 
Published: January 2022

AbstractThe objective of this article is to explore the combined effects of corporate social responsibility (CSR), green transformational leadership and knowledge transfer on responsible green innovation and to analyse their impact on agribusiness business performance in the context of a developing country. There is no research that integrates joint effects on responsible innovation with a focus on process inputs and increased greening capabilities in agricultural units. Moreover, we have integrated transformational green leadership to better explain this impact as a differentiator. Results show both knowledge transfer and green transformational leadership have positive relationships with responsible green innovation, and the latter has a positive impact on environmental, economic and strategic performance dimensions. Overall, our results establish that CSR is an external driver that reinforces knowledge transfer with an emphasis on collaboration. CSR also reinforces green leadership functions through synergies in conjunction with green human resource management practices.
Corporate governance, board connections and remuneration
Authors: Arayakarnkul Pochara , Chatjuthamard Pattanaporn , Lhaopadchan Suntharee , Treepongkaruna Sirimon 
Published: January 2022

AbstractGood corporate governance underpins good corporate social responsibility (CSR) through value‐creating stakeholder relationships. When properly composed and compensated, the board of directors, an important corporate governance mechanism, plays an efficient monitoring role, reducing agency cost. Exploring board connections and remuneration of the top 100 listed firms in the Stock Exchange of Thailand as a case study, we find evidence supporting agency cost of board connections such that politically connected board members are paid higher. However, politically connected board members play an effective monitoring role in setting top management pay, supporting stewardship and resource dependency theories. Our case study highlights the importance of balancing boards of directors' compositions and remunerations to achieve CSR outcomes and value creation among stakeholders.
Systemic nonbiologic treatments for hidradenitis suppurativa
Authors: Greif Charlotte , Gibson Ruby S. , Porter Martina L. 
Published: January 2022

AbstractHidradenitis suppurativa (HS) is a severe and painful chronic dermatologic condition affecting hair follicles with a significant negative impact on patient quality of life. Effective treatment of HS has proven challenging and often involves multiple modalities. These include topical treatments, systemic antibiotics, retinoids, hormonal therapies, biologic and nonbiologic immunosuppressants, small molecule inhibitors, surgery, and photodynamic/radiation therapy. This review outlines the nonbiologic systemic therapies for HS and describes the latest research on these therapies. Therapies covered in this review include systemic antibiotics, retinoids, hormonal therapies, nonbiologic immunosuppressants, and small molecule inhibitors.
Surgical management of hidradenitis suppurativa: A review of techniques, data, and future directions
Authors: Klufas Daniel M. , Saylor Drew K. 
Published: January 2022

AbstractHidradenitis suppurativa (HS) is a debilitating, chronic dermatologic condition that when left untreated can lead to irreversible structural changes in the skin, often manifesting as subcutaneous tunnels, defined as linear tracts that may open onto the skin surface. While medical management may delay architectural damage to the skin, for those patients whose disease has progressed past the point of medical intervention and irreversible tissue damage is present, surgical treatment is a critical component in disease management. Various surgical treatment modalities such as unroofing and excision exist to treat HS surgically, however, the data regarding efficacy and surgical outcomes for these techniques is heterogeneously reported and often of low quality. As such, it is difficult to assess this data and determine what the best surgical option is for an individual patient. This manuscript will focus on categorizing the various types of surgical procedures used in the surgical and procedural management of HS, summarize data on outcomes measures of various treatment modalities, identify current gaps in the literature regarding HS surgery, and outline the necessary steps to address these gaps to standardize and improve the surgical care of all HS patients.
N‐Heterocyclic and Mesoionic Carbenes of Manganese and Rhenium in Catalysis
Authors: Friães Sofia , Realista Sara , Mourão Henrique , Royo Beatriz 
Published: January 2022

AbstractThe use of N‐heterocyclic carbenes (NHCs) in manganese and rhenium catalysis is underdeveloped in comparison to other transition metals. Herein, we cover the recent and stimulating progress in homogeneous catalysis using Mn‐NHC complexes, namely in hydrosilylation, hydrogenation, and borrowing hydrogen processes. Of particular interest is the application of Mn and Re NHC catalysts in the electrochemical and photochemical reduction of CO2.
Decontamination technologies for medicinal and aromatic plants: A review
Authors: Rahmati Edris , Khoshtaghaza Mohammad Hadi , Banakar Ahmad , Ebadi Mohammad‐Taghi 
Published: January 2022

AbstractMicrobial quality assurance has always been an important subject in the production, trade, and consumption of medicinal and aromatic plants (MAPs). Most MAPs have therapeutic and nutritional properties due to the presence of active substances such as essential oils, flavonoids, alkaloids, etc. However, MAPs can become infected with microorganisms due to poor hygienic conditions during cultivation and postharvest processes. This problem reduces the shelf life and effective ingredients of the product. To overcome these problems, several technologies such as using ethylene oxide gas, gamma irradiation, and steam heating have been used. However, these technologies have disadvantages such as the formation of toxic by‐products, low consumer acceptance, or may have a negative effect on the quality of MAPs. This requires a need for novel decontamination technology which can effectively reduce the biological contamination and minimize the food quality losses. In recent years, new technologies such as ozonation, cold plasma, ultraviolet, infrared, microwave, radiofrequency and combination of these technologies have been developed. In this review, biological contamination of MAPs and technologies used for their decontamination were studied. Also, the mechanism of inactivation of microorganisms and the efficacy of decontamination techniques on the qualitative and microbial characteristics of MAPs were investigated.
Effect of electromagnetic field on the thermal performance of longitudinal trapezoidal porous fin using DTM–Pade approximant
Authors: Varun Kumar R. S. , Sarris I. E. , Sowmya G. , Madhukesh J. K. , Prasannakumara B. C. 
Published: January 2022

AbstractThe heat transfer and thermal distribution through porous fins have gotten a lot of attention in recent years due to their extensive applications in the manufacturing and engineering field. In porous fins, the impact of magnetic field aids in improved heat transfer enhancement. Also, the combination of an electric effect and a magnetic field considerably enhances heat transfer. In this direction, the thermal distribution through a convective–radiative longitudinal trapezoidal porous fin with the impact of an internal heat source and an electromagnetic field is discussed in the present analysis. The governing heat equation is nondimensionalized with nondimensional terms, and the transformed nonlinear ordinary differential equation is solved analytically using the DTM–Pade approximant algorithm. Furthermore, the graphical discussion is presented to explore the impact of various nondimensional parameters, such as convection‐conduction parameter, fin taper ratio, thermomagnetic field, radiation–conduction parameter, internal heat generation parameter, and thermoelectrical field on the temperature gradient of the fin. The investigation's key findings disclose that as the magnitude of the convection–conduction parameter, fin taper ratio, and radiation–conduction parameter increase, the thermal distribution through the fin reduces. The thermal distribution inside the fin increases for the heat‐generating parameter, thermoelectric, and thermomagnetic fields.
Neurogenic and pericytic plasticity of conditionally immortalized cells derived from renal erythropoietin‐producing cells
Authors: Bapst Andreas M. , Knöpfel Thomas , Nolan Karen A. , Imeri Faik , Schuh Claus D. , Hall Andrew M. , Guo Jia , Katschinski Dörthe M. , Wenger Roland H. 
Published: January 2022

AbstractIn adult mammals, the kidney is the main source of circulating erythropoietin (Epo), the master regulator of erythropoiesis. In vivo data in mice demonstrated multiple subtypes of interstitial renal Epo‐producing (REP) cells. To analyze the differentiation plasticity of fibroblastoid REP cells, we used a transgenic REP cell reporter mouse model to generate conditionally immortalized REP‐derived (REPD) cell lines. Under nonpermissive conditions, REPD cells ceased from proliferation and acquired a stem cell‐like state, with strongly enhanced hypoxia‐inducible factor 2 (HIF‐2α), stem cell antigen 1 (SCA‐1), and CD133 expression, but also enhanced alpha‐smooth muscle actin (αSMA) expression, indicating myofibroblastic signaling. These cells maintained the “on‐off” nature of Epo expression observed in REP cells in vivo, whereas other HIF target genes showed a more permanent regulation. Like REP cells in vivo, REPD cells cultured in vitro generated long tunneling nanotubes (TNTs) that aligned with endothelial vascular structures, were densely packed with mitochondria and became more numerous under hypoxic conditions. Although inhibition of mitochondrial oxygen consumption blunted HIF signaling, removal of the TNTs did not affect or even enhance the expression of HIF target genes. Apart from pericytes, REPD cells readily differentiated into neuroglia but not adipogenic, chondrogenic, or osteogenic lineages, consistent with a neuronal origin of at least a subpopulation of REP cells. In summary, these results suggest an unprecedented combination of differentiation features of this unique cell type.
Elevated loading at the posterior acetabular edge of dysplastic hips during double‐legged squat
Authors: Song Ke , Pascual‐Garrido Cecilia , Clohisy John C. , Harris Michael D. 
Published: January 2022

AbstractHips with developmental dysplasia (DDH) are at a heightened risk of premature hip osteoarthritis, which is often expedited by mechanically induced articular tissue damage. A prevalent form of damage in DDH is labral tears caused by abnormal loading at the shallow acetabular edge. Although the majority of reported DDH‐related labral tears occur in the antero‐superior acetabulum, posterior labral tears are prevalent in individuals whose lifestyle involves frequent high hip flexion tasks such as squatting. To better understand region‐specific risks for chondrolabral damage during high hip flexion, we used image‐based musculoskeletal models to compare acetabular edge loading (AEL) during double‐legged squat between hips with symptomatic DDH (n = 10) and healthy controls (n = 10). Compared to controls, hips with DDH had higher instantaneous posterior AEL at the lowest point of squat (2.6 vs. 1.8 ×BW, p ≤ 0.04), and higher accumulative loading across the duration of the squatting motion (2.6 vs. 1.9 ×BW*s, p ≤ 0.04). Elevated posterior AEL coincided with increased net hip extension moments and posterior joint reaction forces, and was correlated with the severity of DDH acetabular deformity. Our findings suggest that posterior AEL is elevated in hips with symptomatic DDH during double‐legged squat, which may contribute to chondrolabral damage in individuals who often perform such high hip flexion tasks. Clinical evaluation of DDH should consider patient‐specific anatomy and lifestyle factors when establishing diagnoses and planning personalized treatment.
Chiral separation using cyclodextrins as mobile phase additives in open‐tubular liquid chromatography with a pseudophase coating
Authors: Yu Raymond B. , Quirino Joselito P. 
Published: January 2022

AbstractThe chiral separation of various analytes (dichlorprop, mecoprop, ibuprofen, and ketoprofen) was demonstrated with different cyclodextrins as mobile phase additives in open‐tubular liquid chromatography using a stationary pseudophase semipermanent coating. The stable coating was prepared by a successive multiple ionic layer approach using poly(diallyldimethylammonium chloride), polystyrene sulfonate, and didodecyldimethyl ammonium bromide. Increasing concentrations (0–0.2 mM) of various native and derivatized cyclodextrins in 25 mM sodium tetraborate (pH 9.2) were investigated. Chiral separation was achieved for the four test analytes using 0.05–0.1 mM β‐cyclodextrin (resolution between 1.11 and 1.34), γ‐cyclodextrin (resolution between 0.78 and 1.27), carboxymethyl‐β‐cyclodextrin (resolution between 1.64 and 2.59), and 2‐hydroxypropyl‐β‐cyclodextrin (resolution between 0.71 and 1.76) with the highest resolutions obtained with 0.1 mM carboxymethyl‐β‐cyclodextrin. %RSD values were <10%. This is the first demonstration of chiral open‐tubular liquid chromatography using achiral chromatographic coatings and cyclodextrins as mobile phase additives.
Finding fishers: determining fisher occupancy in the Northern Rocky Mountains
Authors: Krohner Jessica M. , Lukacs Paul M. , Inman Robert , Sauder Joel D. , Gude Justin A. , Mosby Cory , Coltrane Jessica A. , Mowry Rebecca A. , Millspaugh Joshua J. 
Published: January 2022

AbstractMonitoring rare and elusive carnivores is inherently challenging because they often occur at low densities and require more resources to effectively assess status and trend. The fisher (Pekania pennanti) is an elusive mesocarnivore endemic to North America; in its western populations it is classified as a species of greatest conservation need. During winter of 2018–2019, we deployed remotely triggered cameras in randomly selected, spatially balanced 7.5‐km × 7.5‐km grid cells across a broad study area in western Montana, Idaho, and eastern Washington, USA. As part of this large‐scale, multi‐state monitoring effort, we conducted an occupancy assessment of the Northern Rocky Mountain fisher population at a range‐wide scale. We used non‐spatial occupancy models to determine the current extent of fisher occurrence in the Northern Rocky Mountains and to provide baseline occupancy estimates across a broad study area and a refined sampling frame for future monitoring. We used a spatial occupancy model to determine patterns in fisher occurrence across their Northern Rocky Mountain range while explicitly correcting for spatially induced overdispersion. Additionally, we assessed factors that influenced fisher occurrence through covariate occupancy modeling that considered predicted fisher habitat, site‐level environmental characteristics, and the influence of available harvest records (incidental and regulated). We detected fishers in 32 out of 318 (10%) of our surveyed cells, and estimated that overall, 160 (14%; 95% CI = 115–218) of 1,143 grid cells were occupied by fishers. Fisher occupancy was positively associated with our stratum that contained cells with a greater proportion of predicted fisher habitat and with proximity to nearest 2000–2015 harvest location. Fisher occupancy was weakly and positively associated with increased canopy cover. Our spatial model identified 2 areas with higher predicted occupancy: a large area across the Idaho Nez Perce‐Clearwater National Forest, and a smaller area in the Cabinet Mountain Range crossing the northern border of Idaho and Montana. We used spatial occupancy results from our original sampling frame to create a biologically derived refined sampling frame for future monitoring. Within the bounds of our refined sampling frame, we estimated that 155 (22%; 95% CI = 110–209) of 700 grid cells were occupied by fishers. By incorporating our increasing understanding of fisher habitat with contemporary analytical techniques, we defined current range‐wide occupancy of the Northern Rocky Mountain fisher population, identified core areas of fisher occurrence for future conservation efforts, and used our model results to create a refined sampling frame for future fisher monitoring in the Northern Rocky Mountains.
A Protein Composite Neural Scaffold Modulates Astrocyte Migration and Transcriptome Profile
Authors: Yao Li , Brice Ryan , Shippy Teresa 
Published: January 2022

AbstractBioscaffold implantation is a promising approach to facilitate the repair and regeneration of wounded neural tissue after injury to the spinal cord or peripheral nerves. However, such bioscaffold grafts currently result in only limited functional recovery. The generation of a neural scaffold using a combination of collagen and glutenin is reported. The conduit material and mechanical properties, as well as its effect on astrocyte behavior is tested. After neural injuries, astrocytes move into the lesion and participate in the process of remodeling the micro‐architecture of the wounded neural tissue. In this study, human astrocytes grown on glutenin‐collagen scaffolds show higher motility and a lower proliferation rate compared with those grown on collagen scaffolds. RNA sequencing reveals that astrocytes grown on the two types of scaffolds show differentially expressed genes in Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways such as actin cytoskeleton and focal adhesion that regulate astrocyte migration on scaffolds. The gene expression of aggrecan and versican, chondroitin sulfate proteoglycans that inhibit axonal growth, is down‐regulated in astrocytes grown on glutenin‐collagen scaffolds. These outcomes indicate that the implantation of glutenin‐collagen scaffolds may promote astrocyte function in the neural regeneration process by enhanced cell migration and reduced glial scar formation.
Studying Activated Fibroblast Phenotypes and Fibrosis‐Linked Mechanosensing Using 3D Biomimetic Models
Authors: Paradiso Francesca , Quintela Marcos , Lenna Stefania , Serpelloni Stefano , James David , Caserta Sergio , Conlan Steve , Francis Lewis , Taraballi Francesca 
Published: January 2022

AbstractFibrosis and solid tumor progression are closely related, with both involving pathways associated with chronic wound dysregulation. Fibroblasts contribute to extracellular matrix (ECM) remodeling in these processes, a crucial step in scarring, organ failure, and tumor growth, but little is known about the biophysical evolution of remodeling regulation during the development and progression of matrix‐related diseases including fibrosis and cancer. A 3D collagen‐based scaffold model is employed here to mimic mechanical changes in normal (2 kPa, soft) versus advanced pathological (12 kPa, stiff) tissues. Activated fibroblasts grown on stiff scaffolds show lower migration and increased cell circularity compared to those on soft scaffolds. This is reflected in gene expression profiles, with cells cultured on stiff scaffolds showing upregulated DNA replication, DNA repair, and chromosome organization gene clusters, and a concomitant loss of ability to remodel and deposit ECM. Soft scaffolds can reproduce biophysically meaningful microenvironments to investigate early stage processes in wound healing and tumor niche formation, while stiff scaffolds can mimic advanced fibrotic and cancer stages. These results establish the need for tunable, affordable 3D scaffolds as platforms for aberrant stroma research and reveal the contribution of physiological and pathological microenvironment biomechanics to gene expression changes in the stromal compartment.
Self‐Organization Formation of Multicellular Spheroids Mediated by Mechanically Tunable Hydrogel Platform: Toward Revealing the Synergy of Chemo‐ and Noninvasive Photothermal Therapy against Colon Microtumor
Authors: Zhang Yi , Guo Zhao‐bin , Nie Yu‐min , Feng Guan‐ping , Deng Man‐jiao , Hu Yi‐min , Zhang Hui‐jie , Zhao Yin‐yi , Feng Yi‐wei , Yu Ting‐ting , Hu Ke 
Published: January 2022

AbstractThree‐dimensional (3D) tumor cell culture offers a more tissue‐recapitulating model in cancer treatment evaluation. However, conventional models based on cell‐substrate adhesion deprivation are still of insufficient real tumor mimic. In this work, a novel method is proposed for inducing multicellular spheroids (MCSs) formation based on hydrogel with tunable microenvironmental properties. Colon tumor cells DLD1 cultured on hydrogel substrate with proper physical stimulation form MCSs via self‐organization. Chemotherapy based on clinical drug and far‐infrared photothermal therapy is evaluated with DLD1 MCSs obtained by this method. The synergism of chemotherapy and noninvasive photothermal therapy based on graphene device is further verified in MCSs model and it is believed this method holds potential in in vitro anti‐tumor strategies evaluation for precision medicine.