bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kinematics of the Local Group gas and galaxies in the hestia simulations
Authors: Biaus Luis , Nuza Sebastián E , Richter Philipp , Sparre Martin , Scannapieco Cecilia , Damle Mitali , Sorce Jenny G , Grand Robert J J , Tempel Elmo , Libeskind Noam I , Hani Maan H 
Published: October 2022

ABSTRACT
We investigate the kinematic properties of gas and galaxies in the Local Group (LG) using high-resolution simulations performed by the hestia (High-resolution Environmental Simulations of The Immediate Area) collaboration. Our simulations include the correct cosmography surrounding LG-like regions consisting of two main spiral galaxies of ∼1012 M⊙, their satellites and minor isolated galaxies, all sharing the same large-scale motion within a volume of a few Mpc. We characterize the gas and galaxy kinematics within the simulated LGs, from the perspective of the Sun, to compare with observed trends from recent HST/COS absorption-line observations and LG galaxy data. To analyse the velocity pattern of LG gas and galaxies seen in the observational data, we build sky maps from the local standard of rest, and the Galactic and LG barycentre frames. Our findings show that the establishment of a radial velocity dipole at low/high latitudes, near the preferred barycentre direction, is a natural outcome of simulation kinematics for material outside the Milky Way virial radius after removing Galaxy rotation when the two main LG galaxies are approaching. Our results favour a scenario where gas and galaxies stream towards the LG barycentre producing a velocity dipole resembling observations. While our study shows in a qualitative way the global matter kinematics in the LG as part of its ongoing assembly, quantitative estimates of gas-flow rates and physical conditions of the LG gas have to await a more detailed modelling of the ionization conditions, which will be presented in a follow-up paper.
ALMACAL IX: Multiband ALMA survey for dusty star-forming galaxies and the resolved fractions of the cosmic infrared background
Authors: Chen Jianhang , Ivison R J , Zwaan Martin A , Smail Ian , Klitsch Anne , Péroux Céline , Popping Gergö , Biggs Andrew D , Szakacs Roland , Hamanowicz Aleksandra , Lagos Claudia 
Published: October 2022

ABSTRACT
Wide, deep, blind continuum surveys at submillimetre/millimetre (submm/mm) wavelengths are required to provide a full inventory of the dusty, distant Universe. However, conducting such surveys to the necessary depth, with sub-arcsec angular resolution, is prohibitively time-consuming, even for the most advanced submm/mm telescopes. Here, we report the most recent results from the ALMACAL project, which exploits the ‘free’ calibration data from the Atacama Large Millimetre/submillimetre Array (ALMA) to map the lines of sight towards and beyond the ALMA calibrators. ALMACAL has now covered 1001 calibrators, with a total sky coverage around 0.3 deg2, distributed across the sky accessible from the Atacama desert, and has accumulated more than 1000 h of integration. The depth reached by combining multiple visits to each field makes ALMACAL capable of searching for faint, dusty, star-forming galaxies (DSFGs), with detections at multiple frequencies to constrain the emission mechanism. Based on the most up-to-date ALMACAL data base, we report the detection of 186 DSFGs with flux densities down to S870 µm ∼ 0.2 mJy, comparable with existing ALMA large surveys but less susceptible to cosmic variance. We report the number counts at five wavelengths between 870 μm and 3 mm, in ALMA bands 3, 4, 5, 6, and 7, providing a benchmark for models of galaxy formation and evolution. By integrating the observed number counts and the best-fitting functions, we also present the resolved fraction of the cosmic infrared background (CIB) and the CIB spectral shape. Combining existing surveys, ALMA has currently resolved about half of the CIB in the submm/mm regime.
Production of hot Jupiter candidates from high-eccentricity mechanisms for different initial planetary mass configurations
Authors: Garzón H , Rodríguez Adrián , de Elía G C 
Published: October 2022

ABSTRACT
Hot Jupiters (HJs) are giant planets with orbital periods of the order of a few days with semimajor axis within ∼0.1 au. Several theories have been invoked in order to explain the origin of this type of planets, one of them being the high-eccentricity migration. This migration can occur through different high-eccentricity mechanisms. Our investigation focused on six different kinds of high-eccentricity mechanisms, namely, direct dispersion, coplanar, Kozai–Lidov, secular chaos, E1 and E2 mechanisms. We investigated the efficiency of these mechanisms for the production of HJ candidates in multiplanet systems initially tightly-packed in the semimajor axis, considering a large set of numerical simulations of the exact equations of motion in the context of the N-body problem. In particular, we analyzed the sensitivity of our results to the initial number of planets, the initial semimajor axis of the innermost planetary orbit, the initial configuration of planetary masses, and to the inclusion of general relativity (GR) effects. We found that the E1 mechanism is the most efficient in producing HJ candidates both in simulations with and without the contribution of GR, followed by the Kozai–Lidov and E2 mechanisms. Our results also revealed that, except for the initial equal planetary mass configuration, the E1 mechanism was notably efficient in the other initial planetary mass configurations considered in this work. Finally, we investigated the production of HJ candidates with prograde, retrograde, and alternating orbits. According to our statistical analysis, the Kozai–Lidov mechanism has the highest probability of significantly exciting the orbital inclinations of the HJ candidates.
Dust extinction map of the Galactic plane based on the VVV survey data
Authors: Zhang M , Kainulainen J 
Published: October 2022

ABSTRACT
Dust extinction is one of the most reliable tracers of the gas distribution in the Milky Way. The near-infrared (NIR) Vista Variables in the Vía Láctea (VVV) survey enables extinction mapping based on stellar photometry over a large area in the Galactic plane. We devise a novel extinction mapping approach, XPNICER, by bringing together VVV photometric catalogues, stellar parameter data from StarHorse catalogues, and previously published X percentile and PNICER extinction mapping techniques. We apply the approach to the VVV survey area, resulting in an extinction map that covers the Galactic disc between 295° ≲ l ≲ 350° and −2° ≲ b ≲ 2°, and the Galactic bulge between −10° ≲ b ≲ 5°. The map has 30 arcsec spatial resolution and it traces extinctions typically up to AV ∼ 10–20 mag and maximally up to AV ∼ 30 mag. We compare our map to previous dust-based maps, concluding that it provides a high-fidelity extinction-based map, especially in its ability to recover both the diffuse dust component of the Galaxy and moderately extincted giant molecular cloud regions. The map is especially useful as independent, extinction-based data on the Galactic dust distribution and applicable for a wide range of studies from individual molecular clouds to the studies of the Galactic stellar populations.
Efficient analysis routines for single and double peaked Type 2 AGN spectra
Authors: Selwood M , Calderone G , Fotopoulou S , Bremer M N 
Published: October 2022

ABSTRACT
Driven by the imminent need to rapidly process and classify millions of AGN spectra drawn from next generation astronomical facilities, we present a spectral fitting routine for Type 2 AGN spectra optimized for high volume processing, using the quasar spectral fitting library (qsfit). We analyse an optically selected sample of 813 luminous Type 2 AGN spectra at z &lt; 0.83 from the Sloan Digital Sky Survey (SDSS) to qualify its performance. We report a median narrow line H α/H β Balmer decrement of 4.5 ± 0.8, alluding to the presence of dust in the narrow line region (NLR). We publish a specialized qsfit fitting routine for high signal-to-noise ratio spectra and general fitting routine for double peaked Type 2 AGN spectra applied on a subsample of 45 spectra from our parent sample. We report a median red and blue peak velocity separation of 390 ± 60 kms−1. No trend is found for red or blue peaks to exhibit systematically different luminosity or ionization properties. Emission line diagnostics show that the double peaks in all sources are illuminated by an AGN-powered ionizing continuum. Finally, we examine the morphology of host galaxies of our double peaked sample. We find double peaked Type 2 AGN reside in merging systems at a comparable frequency to single peaked AGN. This suggests that the double peaked AGN phenomenon is likely to have a bi-conical outflow origin in the majority of cases. We publicly release the code used for spectral analysis and produced catalogues used in this work.
The sweep method for radiative transfer in arepo
Authors: Peter Toni , Klessen Ralf S , Kanschat Guido , Glover Simon C O , Bastian Peter 
Published: October 2022

ABSTRACT
We introduce the radiative transfer code Sweep for the cosmological simulation suite arepo. Sweep is a discrete ordinates method in which the radiative transfer equation is solved under the infinite speed of light, steady state assumption by a transport sweep across the entire computational grid. Since arepo is based on an adaptive, unstructured grid, the dependency graph induced by the sweep dependencies of the grid cells is non-trivial. In order to solve the topological sorting problem in a distributed manner, we employ a task-based-parallelism approach. The main advantage of the sweep method is that the computational cost scales only with the size of the grid and is independent of the number of sources or the distribution of sources in the computational domain, which is an advantage for radiative transfer in cosmological simulations, where there are large numbers of sparsely distributed sources. We successfully apply the code to a number of physical tests such as the expansion of H ii regions, the formation of shadows behind dense objects, the scattering of light, and its behaviour in the presence of periodic boundary conditions. In addition, we measure its computational performance with a focus on highly parallel, large-scale simulations.
A kinematic excess in the annular gap and gas-depleted cavity in the disc around HD 169142
Authors: Garg H , Pinte C , Hammond I , Teague R , Hilder T , Price D J , Calcino J , Christiaens V , Poblete P P 
Published: October 2022

ABSTRACT
We present ALMA band 6 images of the 12CO, 13CO, and C18O J = 2-1 line emissions for the circumstellar disc around HD 169142, at ∼8 au spatial resolution. We resolve a central gas-depleted cavity, along with two independent near-symmetric ring-like structures in line emission: a well-defined inner gas ring [∼25 au] and a second relatively fainter and diffuse outer gas ring [∼65 au]. We identify a localized super-Keplerian feature or vertical flow with a magnitude of ∼75 ms−1 in the 12CO map. This feature has the shape of an arc that spans azimuthally across a position angle range of −60° to 45° and radially in between the B1[26au] and B2[59au] dust rings. Through reconstruction of the gas surface density profile, we find that the magnitude of the background perturbations by the pressure support and self-gravity terms are not significant enough to account for the kinematic excess. If of planetary origin, the relative depletion in the gas-density profile would suggest a 1 MJ planet. In contrast, the central cavity displays relatively smooth kinematics, suggesting either a low-mass companion and/or a binary orbit with a minimal vertical velocity component.
The role of physical and numerical viscosity in hydrodynamical instabilities
Authors: Marin-Gilabert Tirso , Valentini Milena , Steinwandel Ulrich P , Dolag Klaus 
Published: October 2022

ABSTRACT
The evolution of the Kelvin–Helmholtz Instability (KHI) is widely used to assess the performance of numerical methods. We employ this instability to test both the smoothed particle hydrodynamics (SPH) and the meshless finite mass (MFM) implementation in opengadget3. We quantify the accuracy of SPH and MFM in reproducing the linear growth of the KHI with different numerical and physical set-ups. Among them, we consider: (i) numerical induced viscosity, and (ii) physically motivated, Braginskii viscosity, and compare their effect on the growth of the KHI. We find that the changes of the inferred numerical viscosity when varying nuisance parameters such as the set-up or the number of neighbours in our SPH code are comparable to the differences obtained when using different hydrodynamical solvers, i.e. MFM. SPH reproduces the expected reduction of the growth rate in the presence of physical viscosity and recovers well the threshold level of physical viscosity needed to fully suppress the instability. In the case of galaxy clusters with a virial temperature of 3 × 107 K, this level corresponds to a suppression factor of ≈10−3 of the classical Braginskii value. The intrinsic, numerical viscosity of our SPH implementation in such an environment is inferred to be at least an order of magnitude smaller (i.e. ≈10−4), re-ensuring that modern SPH methods are suitable to study the effect of physical viscosity in galaxy clusters.
Testing for relics of past strong buckling events in edge-on galaxies: simulation predictions and data from S4G
Authors: Cuomo Virginia , Debattista Victor P , Racz Sarah , Anderson Stuart Robert , Erwin Peter , Gonzalez Oscar A , Powell J W , Corsini Enrico Maria , Morelli Lorenzo , Norris Mark A 
Published: October 2022

ABSTRACT
The short-lived buckling instability is responsible for the formation of at least some box/peanut (B/P) shaped bulges, which are observed in most massive, z = 0, barred galaxies. Nevertheless, it has also been suggested that B/P bulges form via the slow trapping of stars on to vertically extended resonant orbits. The key difference between these two scenarios is that when the bar buckles, symmetry about the mid-plane is broken for a period of time. We use a suite of simulations (with and without gas) to show that when the buckling is sufficiently strong, a residual mid-plane asymmetry persists for several Gyrs after the end of the buckling phase, and is visible in simulation images. On the other hand, images of B/P bulges formed through resonant trapping and/or weak buckling remain symmetric about the mid-plane. We develop two related diagnostics to identify and quantify mid-plane asymmetry in simulation images of galaxies that are within 3° of edge-on orientation, allowing us to test whether the presence of a B/P-shaped bulge can be explained by a past buckling event. We apply our diagnostics to two nearly edge-on galaxies with B/P bulges from the Spitzer Survey of Stellar Structure in Galaxies, finding no mid-plane asymmetry, implying these galaxies formed their bulges either by resonant trapping or by buckling more than ∼5 Gyr ago. We conclude that the formation of B/P bulges through strong buckling may be a rare event in the past ∼5 Gyr.
The survival of stellar discs in Fornax-like environments, from TNG50 to real galaxies
Authors: Galán-de Anta Pablo M , Sarzi M , Pillepich A , Ding Y , Zhu L , Coccato L , Corsini E M , Fahrion K , Falcón-Barroso J , Gadotti D A , Iodice E , Lyubenova M , Martín-Navarro I , McDermid R M , Pinna F , van de Ven G , de Zeeuw P T 
Published: October 2022

ABSTRACT
We study the evolution of kinematically defined stellar discs in 10 Fornax-like clusters identified in the TNG50 run from the IllustrisTNG suite of cosmological simulations. We considered disc galaxies with present-day stellar mass M⋆ ≥ 3 × 108 M⊙ and follow their evolution since first entering their host cluster. Very few stellar discs survive since falling in such dense environments, ranging from 40 per cent surviving to all being disrupted. Such survival rates are consistent with what reported earlier for the two more massive, Virgo-like clusters in TNG50. In absolute terms, however, the low number of present-day disc galaxies in Fornax-like clusters could be at odds with the presence of three edge-on disc galaxies in the central regions of the actual Fornax cluster, as delineated by the Fornax3D survey. When looking at the Fornax analogues from random directions and with the same selection function of Fornax3D, the probability of finding three edge-on disc galaxies in any one Fornax-like cluster in TNG50 is rather low, albeit not impossible. We also compared the stellar-population properties near the equatorial plane derived from integral-field spectroscopy for the three edge-ons in Fornax to similar line-of-sight integrated values for present-day disc galaxies in TNG50. For one of these, the very old and metal-rich stellar population of its disc cannot be matched by any the disc galaxies in TNG50, including objects in the field. We discuss possible interpretations of these findings, while pointing to future studies on passive cluster spirals as a way to further test state-of-the-art cosmological simulations.
Galactic satellite systems in CDM, WDM and SIDM
Authors: Forouhar Moreno Victor J , Benítez-Llambay Alejandro , Cole Shaun , Frenk Carlos 
Published: October 2022

ABSTRACT
We investigate the population of bright satellites ($M_{*} \ge 10^{5} \, \mathrm{M}_{\odot }$) of haloes of mass comparable to that of the Milky Way in cosmological simulations in which the dark matter (DM) is either cold, warm, or self-interacting (CDM, WDM, and SIDM, respectively). The nature of the DM gives rise to differences in the abundance and structural properties of field haloes. In WDM, the main feature is a reduction in the total number of galaxies that form, reflecting a suppression of low-mass DM haloes and lower galaxy formation efficiency compared to CDM. For SIDM, the changes are structural, restricted to the central regions of haloes and dependent on the assumed self-interaction cross-section. We also consider different baryonic subgrid physics models for galaxy formation, in which supernova gas blowouts can or cannot induce the formation of a core in dwarf galaxies. Overall, the inclusion of baryons lessen the differences in the halo properties in the different DM models compared to DM-only simulations. This affects the satellite properties at infall and therefore their subsequent tidal stripping and survival rates. None the less, we find slightly less concentrated satellite radial distributions as the SIDM cross-section increases. Unfortunately, we also find that the satellite populations in simulations with baryon-induced cores in CDM and WDM can mimic the results found in SIDM, making the satellite stellar mass and maximum circular velocity functions heavily degenerate on the assumed nature of the DM and the adopted subgrid modelling. These degeneracies preclude using the brightest satellites of the Milky Way to constrain the nature of DM.
Accelerating galaxy winds during the big bang of starbursts
Authors: Hayes Matthew J 
Published: October 2022

ABSTRACT
We develop a new method to infer the temporal, geometric, and energetic properties of galaxy outflows, by combining stellar spectral modelling to infer starburst ages, and absorption lines to measure velocities. If winds are accelerated with time during a starburst event, then these two measurements enable us to solve for the wind radius, similarly to length-scales and the Hubble parameter in big bang cosmology. This wind radius is the vital, but hard-to-constrain parameter in wind physics. We demonstrate the method using spectra of 87 starburst galaxies at z = 0.05 − 0.44, finding that winds accelerate throughout the starburst phase and grow to typical radii of ≈1 kpc in ≈10 Myr. Mass flow rates increase rapidly with time, and the mass-loading factor exceeds unity at about 10 Myr – while still being accelerated, the gas will likely unbind from the local potential and enrich the circumgalactic medium. We model the mechanical energy available from stellar winds and supernovae, and estimate that a negligible amount is accounted for in the cool outflow at early times. However, the energy deposition increases rapidly and ∼10 per cent of the budget is accounted for in the cool flow at 10 Myr, similar to some recent hydrodynamical simulations. We discuss how this model can be developed, especially for high-redshift galaxies.
A novel compound EPIC-0412 reverses temozolomide resistance via inhibiting DNA repair/MGMT in glioblastoma
Authors: Zhao Jixing , Yang Shixue , Cui Xiaoteng , Wang Qixue , Yang Eryan , Tong Fei , Hong Biao , Xiao Menglin , Xin Lei , Xu Can , Tan Yanli , Kang Chunsheng 
Published: October 2022

Abstract

Background
Temozolomide (TMZ) resistance has become an important obstacle affecting its therapeutic benefits. O6-methylguanine DNA methyltransferase (MGMT) is primarily responsible for the TMZ resistance in Glioblastoma multiforme (GBM) patients. In addition, active DNA damage repair pathways can also lead to TMZ resistance. Here, we reported a novel small-molecule inhibitor EPIC-0412 that improved the therapeutic efficacy of TMZ by &#x2028;inhibiting the DNA damage repair pathway and MGMT in GBM via epigenetic pathways.

Methods
The small-molecule compound EPIC-0412 was obtained through high-throughput screening. RNA immunoprecipitation (RIP), chromatin isolation by RNA purification (ChIRP), and chromatin immunoprecipitation (ChIP) assays were used to verify the effect of EPIC-0412. Co-immunoprecipitation (Co-IP) was used to elucidate the interactions of transcription factors at the MGMT promoter region. Animal experiments using a mouse model were performed to verify the efficacy of EPIC-0412 in sensitizing GBM cells to TMZ.

Results
EPIC-0412 physically interrupts the binding of HOTAIR and EZH2, leading to the upregulation of CDKN1A and BBC3, causing cell cycle arrest and apoptosis in GBM cells. EPIC-0412 inhibits DNA damage response in GBM cells through the p21-E2F1 DNA damage repair axis. EPIC-0412 epigenetically silences MGMT through its interaction with the ATF3-p-p65-HADC1 axis at the MGMT promoter region. The application of EPIC-0412 restored the TMZ sensitivity in GBM in vivo experiments.

Conclusion
This study discovered a small-molecule inhibitor EPIC-0412, which enhanced the chemotherapeutic effect of TMZ by acting on the p21-E2F1 DNA damage repair axis and ATF3-p-p65-MGMT axis, providing &#x2028;evidence for combining epigenetic drugs to increase the sensitization toward TMZ in GBM patients.