bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of a urinary catheter as a guidewire to facilitate safe nasotracheal intubation following iatrogenic retropharyngeal perforation
Authors: Xing J. , Zhang Y. , Guan J. , Cai J. , Wu B. , Hei Z. 
Published: December 2022

SummaryNasotracheal intubation facilitates adequate access for surgical procedures in the oral cavity, is not limited by mouth opening and can be better tolerated by patients in intensive care. Complications of nasotracheal intubation can include epistaxis, turbinate injury and sinusitis. Retropharyngeal submucosal perforation by the tracheal tube has also been infrequently reported. Here, we report a case of difficult nasotracheal intubation resulting in retropharyngeal submucosal perforation in a patient with a history of obstructive sleep apnoea listed for uvulopalatopharyngoplasty. To facilitate successful tracheal re‐intubation, we used a soft urinary catheter via the other nostril. In this report, we discuss the reasons why this complication may have occurred, how submucosal perforation could be avoided, and reflect on our management of this rare complication. Difficult nasotracheal intubation can present unique challenges, and airway management plans should be made accordingly.
Metallurgical solid waste modified thermoplastic polyurethane composites: The thermal stability and combustion properties
Authors: Yang Sujie , Liu Xinliang , Tao Yi , Deng Dan , Kan Yongchun , Du Xiaoyan , Liu Xiuyu , Tang Gang 
Published: December 2022

AbstractAs a kind of bulk industrial solid waste, the massive accumulation of iron tailings has caused serious waste of resources and environmental pollution. In this study, a silane coupling agent (KH550) was used to modify the surface of iron tailings to produce MIT, and it was compounded with ammonium polyphosphate (APP) on thermoplastic polyurethane (TPU) to prepare a series of TPU/APP/MIT composites. Thermogravimetric (TG), cone calorimetric (CCT), thermogravimetric infrared, scanning electron microscopy, and Raman techniques were also used to analyze the combustion performance, smoke toxicity, and microscopic morphology. The TG test results showed that the compounding of APP and MIT significantly improved the residual carbon value of TPU composites at 700°C. CCT test results showed that the TPU/APP/MIT composites exhibited excellent flame retardancy and smoke suppression. Compared with pure TPU, PHRR, THR, and TSR of TPU/APP15/MIT10 composite decreased by 85.56%, 87.83%, and 86.17%, respectively, the peak release rates of CO and CO2 decreased by 69.26% and 90.34%, respectively. The above studies showed that APP and MIT have excellent flame retardant and smoke suppression effect on TPU materials, providing more opportunities for the study of TPU composites and metallurgical solid waste utilization.
Controlled curing of resole phenol formaldehyde/unsaturated polyester blends and applying for steel–steel adhesive
Authors: Badr Magd M. , Darwish Mohamed S. A. , El‐Rahman Nasser R. Abd , El‐mesallamy Salwa M. , El‐Shafie Mohamed 
Published: December 2022

AbstractPolymer blending technique is a promising solution for solving some critical industrial problems by gaining new desired properties for the newly formed materials. Blending various ratios of resole phenol formaldehyde (RPF)/unsaturated polyester (USPE), 10, 20, 30, to 90 wt %, were processed to optimize the mixing conditions by controlling time, temperature, and ratio of blending. In addition, the curing conditions of touch dry, full curing, shelf life, hardness and the steel–steel adhesive were investigated. The blend ratio RPF/USPE (70:30) was selected as an optimized sample at 150°C for 50 min. It was characterized by Fourier transform infrared spectroscopy, dynamic mechanical analysis, scanning electron microscopy, X‐ray diffraction, thermogravimetric analysis, and differential scanning calorimeter. The curing process and the interactions between RPF and USPE were studied. Durability with artificial weather aging was evaluated visually and by measuring hardness which confirmed the prepared material is fit for outdoor uses. This work introduces a strategy to control the curing process, enhance the shelf life and adhesion properties for steel–steel adhesives based on RPF/USPE blends.
Einfach Bauen – spart eine Wohnraumlüftungsanlage Kosten und Energie?
Authors: Jarmer Tilmann 
Published: December 2022

AbstractIn Bad Aibling wurden 2020 drei Wohngebäude als Forschungshäuser aus Mauerwerk, Holz und Beton errichtet. Dabei wurde die Komplexität durch einfache Konstruktion und reduzierte Gebäudetechnik verringert. Auf eine Lüftungsanlage wurde verzichtet. In den innenliegenden Bädern wurde eine präsenzgeführte Abluft eingebaut. In der Untersuchung wird der Frage nachgegangen, ob es besser gewesen wäre, eine Wohnraumlüftungsanlage in den Forschungshäusern zu installieren. Vier Varianten werden miteinander verglichen: Szenario A: Fensterlüftung und Badabluft präsenzgeführt (wie gebaut); Szenario B: Fensterlüftung und Badabluft präsenzgeführt mit Grundlüftung; Szenario C: Dezentrale Einzelraumlüfter mit Wärmerückgewinnung; Szenario D: Zentrale Wohnraumbelüftung mit Wärmerückgewinnung. Es wurden Umweltwirkung und die Kosten der jeweiligen Lüftungssysteme verursacht durch Technikeinsatz, Wartung und Betriebsenergie über den Lebenszyklus betrachtet. Szenario A (wie gebaut) schneidet in den untersuchten Dimensionen Kosten, nicht erneuerbare Primärenergie und Treibhauspotenzial jeweils am besten ab. Vor allem die Varianten C und D müssten eine hohe Einsparung beim Wärmebedarf realisieren, um die negativen Umweltwirkungen durch die Wohnraumlüftungsanlagen auszugleichen. Bei Vergleichsmessungen in der Praxis konnten keine entsprechenden Einsparungseffekte ermittelt werden. Eine maschinelle Wohnraumlüftung ist nicht geeignet, um die Umweltwirkung oder die Lebenszykluskosten des Projekts zu verbessern.
Bioactive dietary components—Anti‐obesity effects related to energy metabolism and inflammation
Authors: Bertoncini‐Silva Caroline , Zingg Jean‐Marc , Fassini Priscila Giacomo , Suen Vivian Marques Miguel 
Published: December 2022

AbstractObesity is the result of the long‐term energy imbalance between the excess calories consumed and the few calories expended. Reducing the intake of energy dense foods (fats, sugars), and strategies such as fasting and caloric restriction can promote body weight loss. Not only energy in terms of calories, but also the specific composition of the diet can affect the way the food is absorbed and how its energy is stored, used or dissipated. Recent research has shown that bioactive components of food, such as polyphenols and vitamins, can influence obesity and its pathologic complications such as insulin resistance, inflammation and metabolic syndrome. Individual micronutrients can influence lipid turnover but for long‐term effects on weight stability, dietary patterns containing several micronutrients may be required. At the molecular level, these molecules modulate signaling and the expression of genes that are involved in the regulation of energy intake, lipid metabolism, adipogenesis into white, beige and brown adipose tissue, thermogenesis, lipotoxicity, adipo/cytokine synthesis, and inflammation. Higher concentrations of these molecules can be reached in the intestine, where they can modulate the composition and action of the microbiome. In this review, the molecular mechanisms by which bioactive compounds and vitamins modulate energy metabolism, inflammation and obesity are discussed.
Dendritic cell vaccines improve the glioma microenvironment: Influence, challenges, and future directions
Authors: Zhou Jing , Li Luohong , Jia Minqi , Liao Qianjin , Peng Guiping , Luo Gengqiu , Zhou Yanhong 
Published: December 2022

AbstractIntroductionGliomas, especially the glioblastomas, are one of the most aggressive intracranial tumors with poor prognosis. This might be explained by the heterogeneity of tumor cells and the inhibitory immunological microenvironment. Dendritic cells (DCs), as the most potent in vivo functional antigen‐presenting cells, link innate immunity with adaptive immunity. However, their function is suppressed in gliomas. Therefore, overcoming the dysfunction of DCs in the TME might be critical to treat gliomas.MethodIn this paper we proposed the specificity of the glioma microenvironment, analyzed the pathways leading to the dysfunction of DCs in tumor microenvironment of patients with glioma, summarized influence of DC‐based immunotherapy on the tumor microenvironment and proposed new development directions and possible challenges of DC vaccines.ResultDC vaccines can improve the immunosuppressive microenvironment of glioma patients. It will bring good treatment prospects to patients. We also proposed new development directions and possible challenges of DC vaccines, thus providing an integrated understanding of efficacy on DC vaccines for glioma treatment.
Designer, Programmable DNA‐peptide hybrid materials with emergent properties to probe and modulate biological systems
Authors: Menon Dhruv , Singh Ramesh , Joshi Kashti B. , Gupta Sharad , Bhatia Dhiraj 
Published: December 2022

AbstractThe chemistry of DNA endows it with certain functional properties that facilitate the generation of self‐assembled nanostructures, offering precise control over their geometry and morphology, that can be exploited for advanced biological applications. Despite the structural promise of these materials, their applications are limited owing to lack of functional capability to interact favourably with biological systems, which has been achieved by functional proteins or peptides. Herein, we outline a strategy for functionalizing DNA structures with short‐peptides, leading to the formation of DNA‐peptide hybrid materials. This proposition offers the opportunity to leverage the unique advantages of each of these bio‐molecules, that have far reaching emergent properties in terms of better cellular interactions and uptake, better stability in biological media, an acceptable and programmable immune response and high bioactive molecule loading capacities. We discuss the synthetic strategies for the formation of these materials, namely, solid‐phase functionalization and solution‐coupling functionalization. We then proceed to highlight selected biological applications of these materials in the domains of cell instruction & molecular recognition, gene delivery, drug delivery and bone & tissue regeneration. We conclude with discussions shedding light on the challenges that these materials pose and offer our insights on future directions of peptide‐DNA research for targeted biomedical applications.
Asparagine and dough quality: Gluten strength factors in hard red spring wheat
Authors: Trevisan Susane , Khorshidi Ali Salimi , Sopiwnyk Elaine , Xie Yi , Zhou Zhaoxian , House James D. , Scanlon Martin G. 
Published: December 2022

AbstractBackground and ObjectivesSafety aspects regarding free asparagine concentration in wheat arise because of its acrylamide formation potential in baked wheat products. Free asparagine concentration in wheat is affected by environment, genotype, and nitrogen and sulfur fertilization, which also affect wheat protein content and composition. Changing protein content and composition affects gluten strength, altering product quality. This study investigated how gluten strength was affected by environment, genotype, and fertilization treatments grown under commercially relevant conditions.FindingsEnvironment predominated in affecting dough extensibility and genotype primarily affected resistance to extension, with minimal effects from fertilization treatments. Differences in extensigraph parameters at two resting times segregated genotypes according to gluten strength.ConclusionsFactors affecting free asparagine accumulation in wheat also affect gluten strength. Genotype and environment require primary attention since they play an important role in both wheat safety and quality.Significance and NoveltyThe lack of studies investigating the impact of factors affecting free asparagine concentration on the gluten strength of wheat has implications for the global wheat market. From a novel perspective on dough extensibility and resistance to extension, the effects of environment, genotype, and fertilization on the gluten strength of commercially important wheat varieties are considered in a food safety context.
Fertility‐sparing surgery for borderline ovarian Brenner tumor and subsequent childbirth: First case report and a literature review
Authors: Garofalo Giulia , Bucella Dario , Thomas Dominique , Buxant Frederic 
Published: December 2022

AbstractBorderline ovarian Brenner tumors are rare malignancies mainly diagnosed after menopause. A first pregnancy after fertility‐sparing surgery by laparoscopic unilateral salpingo‐oophorectomy was reported in a previous article. We now report the first baby birth after unilateral salpingo‐oophorectomy for a borderline ovarian Brenner tumor and a review of the literature.
Benign peritoneal cystic mesothelioma mimicking peritoneal tuberculosis
Authors: Soltani Chayma , Abdallah Khalaf Ben , Bouchallouf Yasser 
Published: December 2022

AbstractIn immunodeficient patients with repetitive peritoneal aggression, cystic mesothelioma should be considered as a differential diagnosis to peritoneal tuberculosis that must be ruled out in endemic countries.
Exome sequencing identifies a cryptic chromosome translocation in a family decades after clinical diagnosis of Cornelia de Lange: Case report
Authors: Sekhon Morgan , Brown Stephen 
Published: December 2022

AbstractClinical genetic evaluations are defined by the knowledge and technology available at the time they occur. In the modern era, microarray and exome sequencing are first line tests for clinical geneticists; however, beginning in the late 1970s and continuing until the turn of the past century, a standard genetic evaluation consisted, in many cases, of an examination by a dysmorphologist as well as a conventional karyotype. In general, once a genetic diagnosis is established, it does not get revisited as more advanced methods become available. Clearly, there will be instances in which new technology can modify or change a prior diagnosis. We present a family in which the recent birth of a baby resulted in the establishment of a cytogenetic diagnosis of a different family member whose initial evaluation and clinical diagnosis had occurred three decades earlier. The new genomic findings have profound implications for other family members, and in addition provided the family with a sense of closure.
Synthesis of Propargyl Boranes via Silver Catalyzed Insertion of Alkynyl Carbene into B‐H Bond
Authors: Huo Mengtian , Ning Yongquan , Zheng Xudong , Han Xinyue , Karmakar Swastik , Sun Jing , Bi Xihe 
Published: December 2022

AbstractA silver‐catalyzed insertion reaction of alkynyl carbenes derived in situ by decomposition of alkynyl N‐nosylhydrazones, into a B−H bond is reported. This protocol emerges as a straightforward synthesis of various propargylic boron compounds with up to 95 % yield. The operationally simple method exhibits high functional group tolerance and produces a variety of propargyl boranes which are synthetically useful building blocks. Deuterium labelling experiment and DFT studies show that the reaction proceeds via insertion of alkynyl Ag‐carbene into the B−H bond and generation of silver carbene occurs in the rate‐determining step.
Magnetic Anisotropy and Relaxation of Pseudotetrahedral [N2O2] Bis‐Chelate Cobalt(II) Single‐Ion Magnets Controlled by Dihedral Twist Through Solvomorphism
Authors: Pohle Maximilian H. , Böhme Michael , Lohmiller Thomas , Ziegenbalg Sven , Blechschmidt Louis , Görls Helmar , Schnegg Alexander , Plass Winfried 
Published: December 2022

AbstractThe methanol solvomorph 1 ⋅ 2MeOH of the cobalt(II) complex [Co(LSal,2−Ph)2] (1) with the sterically demanding Schiff‐base ligand 2‐(([1,1′‐biphenyl]‐2‐ylimino)methyl)phenol (HLSal,2−Ph) shows the thus far largest dihedral twist distortion between the two chelate planes compared to an ideal pseudotetrahedral arrangement. The cobalt(II) ion in 1 ⋅ 2MeOH exhibits an easy‐axis anisotropy leading to a spin‐reversal barrier of 55.3 cm−1, which corresponds to an increase of about 17 % induced by the larger dihedral twist compared to the solvent‐free complex 1. The magnetic relaxation for 1 ⋅ 2MeOH is significantly slower compared to 1. An in‐depth frequency‐domain Fourier‐transform (FD‐FT) THz‐EPR study not only allowed the direct measurement of the magnetic transition between the two lowest Kramers doublets for the cobalt(II) complexes, but also revealed the presence of spin‐phonon coupling. Interestingly, a similar dihedral twist correlation is also observed for a second pair of cobalt(II)‐based solvomorphs, which could be benchmarked by FD‐FT THz‐EPR.
One Carbon Ring Expansion of Bipyrrole to Bipyridine Enables Access to a π‐Extended, Non‐innocent, Corrole‐like Ligand
Authors: Samala Srinivas , Lee Ji Hye , Park Yeonju , Hong Seong‐Jin , Jo Hongil , Hwang Hyonseok , Jung Young Mee , OK Kang Min , Sessler Jonathan L. , Lee Chang‐Hee 
Published: December 2022

AbstractA π‐extended, diaza‐triphenylene embedded, mono‐anionic corrole analogue and its NiII complex were synthesized from a diaza‐triphenylene precursor, which was obtained from a double one‐carbon insertion into a naphthobipyrrole diester. Following conversion to the corresponding activated diol and acid‐catalyzed condensation with pyrrole, subsequent reaction with pentafluorobenzaldehyde afforded mono‐anionic, π‐extended bipyricorrole‐like macrocycle. Attempted NiII insertion with Ni(OAc)2 ⋅ 4H2O resulted an ESR active, NiII bipyricorrole radical complex, which was converted to a stable cationic NiII complex upon treatment with [(Et3O)+(SbCl6)−]. Both complexes were characterized by 1H and 13C NMR, UV/Vis spectroscopy and single crystal X‐ray diffraction analysis. The NiII bipyricorrole radical complex is converted to a cationic NiII complex by single‐electron reduction using cobaltocene. Both the cationic NiII complex and the radical NiII complex exhibited ligand‐centered redox behavior, whereas the NiII remains in the +2 oxidation state.
Detection of the Dark States in Thermally Activated Delayed Fluorescence (TADF) Process of Electron Donor‐Acceptor Dyads: Insights from Optical Transient Absorption Spectroscopy
Authors: Zhang Xue , Zhao Xiaoyu , Ye Kaiyue , Zhao Jianzhang 
Published: December 2022

AbstractThe photophysical processes involved in the electron donor‐acceptor thermally activated delayed fluorescence (TADF) emitters are complicated and controversial. The recent consensus is that at least three states are involved, i. e. the singlet charge transfer state (1CT), the triplet localized excited state (3LE) and the triplet CT state (3CT). It is clear the very often used steady state and time‐resolved luminescence spectroscopic methods are unable to present direct evidence for the dark states, i. e. the 3LE and 3CT states, as well as the interconversion of these states. Concerning this aspect, the femtosecond‐nanosecond transient absorption spectroscopic methods are in particular interests. Both the emissive state and the dark state can be detected in these spectra, and interconversion of the states involved in TADF process can be also revealed. This review article focuses on the recent development of using the transient absorption spectra to study the photophysics of the TADF emitters.
Hydrodynamics of inhomogeneous agglomerates for a fractal dimension of 2.5 at intermediate Reynolds numbers: Effect of agglomerate sizes and Reynolds numbers
Authors: Yan Jinglu , Wang Yongxin , Liu Huanpeng , Wang Shaowei 
Published: December 2022

AbstractIn this study, the effect of agglomerate sizes for a fractal dimension (Df) of 2.5 on the hydrodynamics at intermediate Reynolds numbers (Re) of 1–120 was assessed. The results show that a core behaves like a solid sphere that exists in the central region inside the agglomerate. In addition, increasing the agglomerate diameter represents adding an extra permeable layer outside the agglomerate. For a larger Re or a smaller agglomerate diameter, the fluid can enter and penetrate through the agglomerate more easily, and the hydrodynamic characteristics of agglomerates deviate more from those of solid spheres. The effect of diameters on the velocity and pressure profiles becomes less significant with the increase in the diameter. Based on the simulated results, the drag ratio has an approximately linear relationship with Re, and its intercept has an exponential relationship with the dimensionless agglomerate diameter. Compared with homogeneous porous spheres, the drag ratio of the agglomerate is different. The effect of diameters on the drag ratio decreases as the diameter increases. It should be noted that the effect of radially varying permeability on inhomogeneous agglomerates should not be ignored and that the effect weakens as Re increases.
Recent Progress on OrganicNear‐InfraredPhotodetectors: Mechanism, Devices, and Applications†
Authors: Wang Qingkai , Zhang Yajie , Wei Zhixiang 
Published: December 2022

Comprehensive SummaryNear infrared light organic photodetectors have attracted tremendous attention due to their tailorable response, ease of processing, compatibility with flexible substrate, room temperature operation and broad applications such as remote sensing, health monitoring, artificial vision, night vision, and so on. Recently, the great improvement obtained on the important figures of merit performances has made organic photodetectors catch up and even surpass those of inorganic photodetectors in some respects. In this review, after a brief illustration of the organic photodetectors' figures of merit performances, we summarize the research progress of panchromatic and narrowband near infrared light organic photodetectors from their working mechanism, strategies to achieve narrowband near infrared light organic photodetectors, to some practical applications. Finally, we discuss the development challenge of the near infrared light organic photodetectors.
Kinetic Salt Effect on Base‐Catalyzed Isomerization of d‐Glucose into d‐Fructose
Authors: Fischer Matthias , Drabo Peter , Burow Lutz , Delidovich Irina 
Published: December 2022

AbstractIsomerization of d‐glucose (Glc) into d‐fructose (Fru) is of great importance for food sector as well as for valorization of lignocellulosic biomass. Soluble and solid bases exhibit high catalytic activity for the isomerization. Here, we report a salt effect on the base‐catalyzed aqueous‐phase Glc‐Fru isomerization. Addition of soluble salts (Na2SO4, NaNO3, K2SO4, and NaCl) results in an increased apparent reaction rate (factors of 1.5 to 6). The salt effect was observed both in the presence of soluble base NaOH at constant pH value and solid bases MgO, Li3PO4, and Mg−Al hydrotalcite. Apparent activation energy and UV absorption spectra were not significantly influenced by addition of salts. Potentiometric titration showed that the acidity constants of the saccharides increase in the presence of electrolytes. Since the rate of the isomerization depends on the thermodynamic acidity constant of Glc, the isomerization is accelerated by the presence of electrolytes.