bluuebunny/crossref_metadata_2025_split huggingface dataset:
Short peripheral intravenous cannula and straight-tip guide wire in ultrasound-guided neonatal central venous catheterization
Authors: Jia Haitao , Zhang Kai , Han Jie , Liu Qi , Chen Peizhang , Wang Yingbin , Huang Shenghui 
Published: April 2022

Background: Inserting a J-tip guide-wire into a vein’s lumen is often difficult when using the Seldinger or modified Seldinger technique for central venous catheterization (CVC) in newborns. This study was designed to compare the efficacy and safety of guide-wire insertion using the combination of a short peripheral intravenous cannula with a straight-tip guide-wire vs. a needle with a J-tip guide-wire for ultrasound-guided (USG) cannulation of the internal jugular vein (IJV) in newborns using an in-plane technique. Methods: One hundred and thirty newborn patients (weight, 1.4-5.2 kg) scheduled for selective or emergency surgery, were randomly assigned to either the needle group (combined with a J-tip guide-wire) or cannula group (combined with a straight-tip guide-wire). The primary outcome was the rate of successful guide-wire insertion on the first attempt. The puncture attempts, catheter placement attempts, and mechanical complications were also compared between the groups. Results: The rate of successful guide-wire insertion on the first attempt was higher in the cannula group (97%) than in the needle group (76%) ( p < 0.05, χ2 = 11.233). Moreover, fewer insertion attempts were needed in the cannula group (1.0 ± 0.2) than in the needle group (1.7 ± 1.1) ( p < 0.05, 95% CI [0.449, 1.028]). The time to successful guide-wire insertion was shorter in the cannula group (63 ± 32 s) than in the needle group (92±50 s) ( p < 0.05, 95% CI [14.024, 43.063]). No differences were found about other catheterization parameters and complications between the groups. Conclusion: The short peripheral cannula combined with a straight-tip guide-wire was superior to the needle combined with a J-tip guide-wire for USG newborn IJV catheterization in terms of successful guide-wire insertion on the first attempt and overall number of insertion attempts.
The sensory experiences of autistic people: A metasynthesis
Authors: Sibeoni Jordan , Massoutier Laura , Valette Marie , Manolios Emilie , Verneuil Laurence , Speranza Mario , Revah-Levy Anne 
Published: April 2022

Qualitative literature reports the sensory experiences of autistic individuals in the first person. Following a thematic synthesis procedure, this metasynthesis aimed to explore specifically the lived experience of these sensory features. Four databases were systematically searched for qualitative studies describing sensory issues reported by autistic individuals. Article quality was assessed with the Critical Appraisal Skills Programme. Thematic analysis was used to identify and synthesise key themes. The 32 articles included reported data from 430 participants. Data analysis produced two themes structuring the sensory experiences of autistic people: (1) the everyday experience through body, thoughts and emotions, and (2) the relational experience, relationships being experienced as both a problem and a solution. Four dimensions are found in our results: physical, emotional, relational and social. Whereas a scientific approach to the sensory experience of autistic people is based on a cause–effect model, our results suggest that autistic people experience these dimensions holistically, as inseparable, and not in terms of cause and effect. This original finding brings new research perspectives, beyond the dichotomy between sensory features and social communications issues, and concrete implications within the health care system to provide more effective and respectful care to autistic people. Lay abstract Sensory atypicalities are very common among autistic people and are integrated in several theories and explanatory models of autism. Qualitative studies have explored these singular sensory experiences from the perspectives of autistic people themselves. This article gathers all these qualitative studies and provides original findings regarding the everyday sensory experience of autistic people, that is, around four dimensions – physical, emotional, relational and social – experienced holistically, as inseparable, and not hierarchically or in terms of cause and effect. Adopting this holistic view could improve the adaptation of the sensory environment in health care facilities and the training of professionals around this specific issue.
Association between loneliness, self-esteem and outcome of life satisfaction in Norwegian adolescents aged 15–21
Authors: Moksnes Unni K. , Bjørnsen Hanne N. , Ringdal Regine , Eilertsen Mary-Elizabeth B. , Espnes Geir Arild 
Published: April 2022

Aims: Adolescence is an important developmental stage for understanding the role of perceived loneliness and self-esteem on life satisfaction. This study investigated the association between loneliness, self-esteem and the outcome of life satisfaction, as well as potential interaction effects in association with life satisfaction, in a sample of Norwegian adolescents. Methods: The study was based on a cross-sectional sample of 1816 adolescents aged 15–21 years. Data were collected in September 2016. The participants reported scores on the five-item Satisfaction with Life Scale, the 10-item Rosenberg Self-Esteem Scale and one item assessing loneliness. Control variables included sex, age, perceived family economy, parents’ education, place of birth and perceived bullying. The data were analysed with descriptive and multiple linear regression analysis. Results: A significant negative and moderately strong association was found between loneliness and life satisfaction, where the association was stronger for girls than for boys. Self-esteem showed a significant positive and strong association with life satisfaction; however, no significant interaction effect was found. Conclusions: The findings show the significant role of both loneliness and self-esteem in association with adolescents’ perception of life satisfaction. The findings support promoting self-esteem, belongingness and social integration in all daily life contexts for adolescents to support their life satisfaction.
Osthole-Mediated Inhibition of Neurotoxicity Induced by Ropivacaine via Amplification of the Cyclic Adenosine Monophosphate Signaling Pathway
Authors: Wang WeiBing , Zhou Hui , Sun LaiBao , Li MeiNa , Gao FengJiao , Sun AiJiao , Zou XueNong 
Published: April 2022

Background Ropivacaine is widely used for clinical anesthesia and postoperative analgesia. However, the neurotoxicity induced by ropivacaine in a concentration- and duration-dependent manner, and it is difficult to prevent neurotoxicity. Osthole inhibits phosphodiesterase-4 activity by binding to its catalytic site to prevent cAMP hydrolysis. The aim of this present study is to explore the precise molecular mechanism of osthole-mediated inhibition of neurotoxicity induced by ropivacaine. Methods: SH-SY5Y cell viability and apoptosis were measured in different concentration and duration. Protein concentration was determined in each signaling pathway. The molecular mechanism of osthole-mediated inhibition of ropivacaine-caused neurotoxicity was evaluated. Results The study demonstrated that osthole inhibits SH-SY5Y cells neurotoxicity in a duration- and concentration-dependent manner. Moreover, ropivacaine significantly increased the expression of caspase-3 by promoting the phosphorylation of p38. Osthole-induced upregulation of cAMP activated cAMP-dependent signaling pathway, sequentially leading to elevated cyclic nucleotide response element-binding protein levels, which inhibits P38-dependent signaling and decreases apoptosis of SH-SY5Y. Conclusions This study display the evidence confirmed the molecular mechanism by which osthole amplification of cAMP-dependent signaling pathway, and overexpression of cyclic nucleotide response element-binding protein inhibits P38-dependent signaling and decreases ropivacaine-induced SH-SY5Y apoptosis.
Angiographic predictors of spontaneous obliteration of transarterial partially embolized brain arteriovenous malformations
Authors: Sultan Ahmed , Hassan Tamer , Metwaly Tamer Ibrahim 
Published: April 2022

Background Spontaneous obliteration of cerebral arteriovenous malformations is uncommon but could occur after partial embolization. Methods A retrospective study of 140 patients that underwent embolization for cerebral AVMs from 2005 to August 2019 using liquid embolic agents. The angiographic outcome of patients was classified as regard complete embolization, partial embolization, and complete obliteration after partial embolization. The parameters studied included size, location, number of arterial feeders, number of draining veins, rupture status, embolic agent, and patient factors as well. Results The study patients included 74 (53%) females and 66 (47%) males. Their age ranged from 7 to 43 years old. One hundred and eight patients (77%) presented with hemorrhage. The AVM grades were grade II in 57 (40.7%) patients and grade III in 56 (39.3%) patients. Sixty-one (43.57%) patients were treated by n-Butyl Cyanoacrylate and 71 (50.71%) patients were treated with Onyx, and both materials were used together in 8 cases. Follow-up angiography was done from 6 to 36 months after embolization. The rate of complete occlusion in all patients was 61.43% (86 patients). There were three groups of patients, the first group had complete occlusion of the nidus at the time of embolization and included 68 (48.57%) patients. The second group had partial embolization with partial occlusion of the nidus 54 patients (38.57%). The 3rd group included 18 patients (12.85%) with complete nidal occlusion on follow up after partial embolization. The delay in the venous drainage of the AVM to the late arterial phase or early venous phase with flow stasis was a significant predictor of future obliteration on follow up after partial embolization. Other significant parameters that were associated with the progressive disappearance of the AVM nidus on follow up after partial embolization are presentation with hemorrhage, AVMs size less than 3 cm, the presence of single draining or double draining veins, superficial venous drainage, and one or 2 arterial feeders. Conclusion Spontaneous closure of intracranial arteriovenous malformations after partial embolization may be encountered in cases of stasis of flow during embolization procedure with a delay of the venous drainage. A long-term follow-up of more cases over many years is required to confirm the validity of this conclusion.
Usage of a percutaneous closure device to repair an iatrogenic subclavian artery injury
Authors: Kent Johnathan , Zarifa Rolla , Pocivavsek Luka 
Published: April 2022

Objectives Inadvertent subclavian artery cannulation during attempted subclavian central venous access is more likely to occur during rushed trauma resuscitations when anatomic landmarks are used for placement. Traditional supraclavicular and infraclavicular approaches for direct repair of the resultant arteriotomy are painful, morbid procedures that should be replaced with more minimally invasive techniques. Methods This case report describes the usage of a percutaneous suture-mediated device (Perclose Proglide, Abbott Laboratories) to repair an iatrogenic subclavian artery arteriotomy. Results Two patients had their injuries successfully repaired using a percutaneous closure device. Conclusions The use of a percutaneous closure device to repair iatrogenic subclavian artery injuries is a safe and effective method of repair that precludes a more invasive exposure and repair.
Spatiotemporal Coexistence of Mesopredators and Their Prey in a Defaunated Neotropical Rainforest
Authors: Flores-Martínez José Juan , Coates Rosamond , Sánchez-Cordero Víctor , Ríos-Solís Jesús Alejandro , Luna-Olivera Beatriz Carely , Ramírez-Ibáñez Marcelino , Lavariega Mario C. 
Published: April 2022

Background and Research Aims Forest loss and fragmentation have a negative impact on large-sized predators and prey, whose populations are reduced or extirpated locally. We explored the spatiotemporal coexistence of the mesopredators (< 15 kg) coyote, ocelot, and white-nosed coati, with their potential prey (< 15 kg) Mexican agouti, lowland paca, and collared peccary in a defaunated rainforest. Methods We used two-species occupancy-detection models between mesopredators and their potential prey, overlap index of circular models, and latency time measurements to evaluate temporal and spatial segregation and habitat use of species. Results Presence of ocelot and coyote was influenced by an increase in the detectability and occupancy of the Mexican agouti. Among most mesopredator–prey species pairs, the correlation for both the capture rates at camera-trap stations and the 1-hr intervals were mainly moderate or low. Some mesopredator–prey species pairs showed low or inverse correlations suggesting species avoidance. The Mexican agouti exhibited a significant negative correlation with the presence of mesopredators. The coyote and ocelot showed a positive correlation with their use of low use trails by people. Conclusions Spatiotemporal tolerance was observed among mesopredator omnivores and prey herbivores. High temporal overlap of ocelots and potential prey (lowland paca) was observed compared to other tropical forests holding large-sized predators, suggesting behavioral shifts for increasing mesopredator–prey encounters. Furthermore, mesopredator coexistence was mediated by a displacement in the temporal peaks of activity and spatial segregation among species. Implications for Conservation Defaunated tropical forests need protection to ensure the conservation of remaining species and their ecological interactions.
Adopting low dose CT in evaluating renal calculi-progress from 2008-18 in a large UK tertiary hospital
Authors: Raynor Richard , Rajesh Arumugam 
Published: April 2022

Background: Computed tomography (CT) of the urinary tract is a commonly performed investigation and it is crucial to adhere to low dose protocols to avoid unnecessary radiation burden. Aims: To review the adoption of low-dose techniques over time, defined as a dose length product (DLP) < 200mGy.cm, in a large teaching hospital over three locations with 12 CT scanners. Methods: Data were obtained from the radiology information system for exams completed under the coding for unenhanced CT evaluation for renal calculi between 14 Feb 2008 and 31 December 2018. Examinations where the DLP was not correctly recorded, was below 40mGy.cm, or where the equipment used could not be identified were excluded. The distribution of doses and the median DLP per scanner was calculated. Results: In all, 20,080 studies were available across 12 CT scanners in the 10- year period. The average Median DLP has reduced from 501mGy.cm in 2008 to 178mGy.cm in 2018. Conclusions: Improvements in CT technology and implementation of low-dose protocols have resulted in significantly lower doses for evaluation of kidney stones since 2008. Although this study demonstrates significant variation between scanners, the overall adoption of low dose techniques is excellent. Level of evidence: Not applicable
Measuring intraobserver and intermethod reliability of endometriotic cyst volumes: A comparison between MRI and 3D transvaginal ultrasound in endometriosis
Authors: Bergwerff Jasmijn , Schreurs Anneke M. F. , Lier Marit C. I. , van Waesberghe Jan Hein T. M , van der Houwen Lisette E. E. , Mijatovic Velja 
Published: April 2022

Objectives: To identify the intraobserver and intermethod reliability of three-dimensional transvaginal ultrasound (3D-TVUS) using the software VOCAL and XI VOCAL compared with magnetic resonance imaging (MRI) for volumetric measurement of ovarian endometrioma. Methods: The intermethod and intraobserver reliability of endometrioma volumes were assessed in 16 women diagnosed with endometriosis through laparoscopy with histologic confirmation and presenting with uni- or bilateral endometriomas. In total, volumes of 23 endometriomas were assessed with two-dimensional and three-dimensional transvaginal ultrasound and 6 mm magnetic resonance imaging. Examinations took place at two moments in one menstrual cycle: day 2–4 (T0) and day 20–22 (T1). Results: The intraclass correlation for intraobserver reliability is good to very good for all three techniques ranging from the lowest value of 0.953 to the highest of 1.000. MRI has the most narrow limits of agreement (−3.93 to 4.53), followed by XI VOCAL (−5.16 to 5.65) while VOCAL has the widest limits of agreement (−10.22 to 11.39). Intraclass correlations are poor in the comparison of XI VOCAL to MRI, moderate between VOCAL and XI VOCAL, and good for the comparison between VOCAL and MRI. Limits of agreement vary per technique. When comparing 3D imaging techniques with 2D TVUS, XI VOCAL versus 2D TVUS provide the smallest limits of agreement. Conclusions: MRI and XI VOCAL provide the best intraobserver reliability. The different imaging techniques are not interchangeable. As TVUS is a more readily available and cost-efficient imaging technique the usage of XI VOCAL is advised.
Correlation of Press Ganey Scores With Early Patient Satisfaction After Anterior Cruciate Ligament Reconstruction
Authors: Kung Justin E. , Zhang Tina , Weir Tristan B. , Schneider Matheus B. , Aneizi Ali , Leong Natalie L. , Packer Jonathan D. , Meredith Sean J. , Henn R. Frank 
Published: April 2022

Background: Patient satisfaction metrics are commonly used to assess the quality of health care and affect reimbursement. The Press Ganey Ambulatory Surgery (PGAS) is a satisfaction survey that has emerged as a prominent quality assessment tool; however, no data exist on whether PGAS scores correlate with early postsurgical satisfaction during the PGAS survey administration period in patients who underwent anterior cruciate ligament reconstruction (ACLR). Purpose: To determine if PGAS scores correlate with measures of satisfaction and patient-reported outcomes (PROs) at 2 weeks postoperatively in ACLR patients. Study Design: Cohort study (diagnosis); Level of evidence, 3. Methods: A retrospective review of patients who underwent ACLR at a single institution was performed. Patients who completed the PGAS survey and PROs at 2 weeks postoperatively were included in the study. Surgical satisfaction was measured with the Surgical Satisfaction Questionnaire (SSQ-8), and PROs included 6 Patient-Reported Outcomes Measurement Information System domains. Bivariate analysis between PGAS and PRO scores was conducted using the Spearman rank correlation coefficient ( r S). Results: Of the 716 patients who received the PGAS survey after ACLR, 81 patients completed the survey, and 39 patients also completed PROs and were included in the study. Total converted (mean scaled score) and “top box” (percentages of questions with highest rating selected) PGAS scores showed no significant correlations with the SSQ-8 ( r S =–0.24; P = .14). There were no significant correlations between SSQ-8 and PGAS domain scores except for a negative correlation with Facility domain top box scores ( r S =–0.33; P = .04), meaning that patients with higher surgical satisfaction had lower PGAS Facility scores. Total PGAS (converted and top box scores) and PGAS domain scores showed no significant correlation with any of the other PROs. Conclusion: PGAS scores showed no significant positive correlation with surgical satisfaction, function, pain, mental health, activity, or expectations of surgery in patients 2 weeks after ACLR. This suggests little to no relationship between PGAS score and surgical satisfaction in the early recovery period after ACLR.
Socioeconomic Status and Toothbrushing in Indigenous and Non-Indigenous Australian Children
Authors: Fernando C. , Ha D.H. , Do L.G. , Tadakamadla S.K. 
Published: April 2022

Introduction: Dental caries in children is a multifactorial and complex condition. Toothbrushing helps maintain good oral hygiene and delivers fluoride. However, determinants of toothbrushing could vary based on Indigenous status. Objective: This study aimed to assess the association between socioeconomic status and adequate toothbrushing practice (brushing twice or more a day) in Indigenous and non-Indigenous Australian children. Methods: Data were acquired from the National Child Oral Health Survey (NCOHS) 2012 to 2014. NCOHS administered questionnaires to parents of a representative sample of 24,215 Australian children aged 5 to 14 y recruited using a complex sampling method. Data on the frequency of toothbrushing and socioeconomic status were collected through the questionnaires. Statistical analysis was conducted progressively from bivariate to multivariable regression modeling, stratified by Indigenous status. Results: Just over half of Indigenous children and over two-thirds of non-Indigenous children reported adequate toothbrushing. The prevalence of adequate brushing (twice or more a day) was 42% (95% confidence interval [CI], 1.10–1.84) higher among children with an overseas-born parent than those with Australian-born parents. Among non-Indigenous children, sex and age, parents’ country of birth, number of children in the family, and other family socioeconomic indicators (education, income, private health insurance) were associated with adequate toothbrushing. The prevalence of adequate brushing was 1.09 (95% CI, 1.03–1.15) and 1.15 (95% CI, 1.10–1.21) times higher when their parent possessed vocational training and tertiary education, respectively, compared to those children whose parents had school-level education. Conclusions: There were differences in patterns of socioeconomic disparities for toothbrushing practices between Indigenous and non-Indigenous Australian children. Knowledge Transfer Statement: To promote positive toothbrushing practices in children, dental clinicians and public health professionals must be aware of the determinants of toothbrushing practices. Socioeconomic disparities in toothbrushing frequency were more apparent in non-Indigenous children. These results will help develop population-specific interventions that tackle the determinants to help improve oral hygiene behavior in Indigenous and non-Indigenous children.