bluuebunny/crossref_metadata_2025_split huggingface dataset:
La vida humana entre la perfección y la caída según san Agustín
Authors: Calabrese Claudio 
Published: October 2022

In this analysis of St. Augustine’s concept of natural law, the focus
will be on the way he presents, in a continuous development,
the ideas of moral compulsion and personal growth. In Augustine’s
interpretation of the biblical text, the foundations of natural
law are provided, such that morality is not simply the fruit of consensus. Man is seen not only as a product of history, even though he cannot be understood outside of it. The natural order and the supernatural order are this way tied together.
Pequeña museografía sobre ilustraciones a la obra de Quevedo
Authors: Marigno Emmanuel 
Published: October 2022

Este trabajo pretende modestamente brindarle al lector enamorado de esa contemplación y quietud que albergan los museos, una pequeña museografía sobre ilustraciones (1966-1982) a la obra de Quevedo.
Se ordenan dichas obras, principalmente estampas, según un criterio básicamente plástico: aguafuerte, litografía y xilografías. Un paseo, que se espera ameno, por el mundo del arte quevedesco.
Evaluation of Teachers’ Knowledge in Tokat Province Before, Immediately After and 6 Months After Basic Life Support Training
Authors: BAYAZIT Elif , BAŞOL Nurşah , KARAMAN Serhat , HASGÜL Burak 
Published: October 2022

Aim: In our study, it was aimed to determine the knowledge levels of teachers about BLS and the factors affecting them, along with detecting the short and long term effects of education with the evaluations made after the training.
Material and Method: This descriptive study’s sample consisted of 134 teachers working in Tokat province. Teachers were educated on BLS using CPR manikins. A total of 3 measurements were made; before, immediately after and 6 months after the training.
Results: It was determined that the teachers had considerable deficiencies in their level of BLS knowledge before the training and a statistically significant increase was observed in their level of BLS knowledge after the training compared to before the education. At the 6th month after the training, the level of BLS knowledge was found to be significantly higher than the pre-training scores .
Conclusion: There is a need for the training of BLS, which will be given to teachers and other saviors among the people, with the intention of raising awareness about BLS and informing society. In order to keep the information up to date, it is necessary to provide BLS training at certain intervals.
Changes in Treatment Adherence During the COVID-19 Pandemic in Patients with Severe Asthma Receiving Biologic Agent Treatment
Authors: ATEŞ Hale , KOCA KALKAN İlkay , AKSU Kurtuluş , TOPEL Musa , YEŞİLKAYA Selma , DEMİR Şenay , NAZİK BAHÇECİOĞLU Sakine 
Published: October 2022

Aim: This study aimed to evaluate the effects of the COVID-19 pandemic on treatment adherence in patients with severe asthma who were receiving omalizumab and mepolizumab treatment in our clinic.
Material and Method: A total of 53 patients with severe asthma, 45 of whom were using omalizumab and 8 of whom were using mepolizumab, were included in the study. The medical records of the patients were recorded anonymously and retrospectively.
Results: It was seen that the rate of patients using omalizumab in the study population decreased during the pandemic period compared to the 1-year period before the pandemic. It was observed that approximately 51% of the patients using omalizumab missed routine treatment doses. The major factor in skipping treatment doses was the fear of contracting COVID-19 upon admission to the hospital. In the mepolizumab group, the rate of using biologic agents during the pandemic period increased compared to 1 year before the pandemic. Dose skipping was observed among 37.5% of the patients in this group and it was found that the major risk factor for skipping a dose was the fear of contracting COVID-19 upon admission to the hospital.
Conclusion: In this study, it was found that there was a decrease in the duration and rate of use of biologic agent therapies administered in a health institution under the supervision of a healthcare professional among patients with severe asthma during the pandemic.
A WITHIN-SUBJECT COMPARISON OF HEARING AID PERFORMANCE IN NOISE BASED ON VERBAL RESPONSE TIMES
Authors: Cristiani Horacio , Alonso Sabrina 
Published: October 2022

BackgroundVerbal response times (VRTs) are among the suggested markers for cognitive load during word recognition tasks. Measurements of VRT during hearing aid fitting can be a useful tool to obtain information about listening effort with different amplification parameters.Material and methodsA software program was developed to easily measure VRTs in speech recognition tests. The system plays 50 randomly chosen recorded words out of a set of 700 disyllables. Speech material can be presented together with pre-selected noise samples at different speech-to-noise ratios and processed with low-pass filters with selectable cut-off frequencies. The test is carried out in free field. A voice activity detector measures the time between the offset of the presented word and the onset of the repetition by the subject, which allows VRT and speech recognition scores to be quickly assessed. Tests were carried out with a group of 8 normal-hearing subjects to evaluate the effect of different filter parameters and a second group of 8 normal-hearing people to evaluate the effect of different speech-to-noise ratios on VRT. Finally, a group of 15 adult hearing-impaired subjects who used hearing aids were fitted under different conditions and the VRTs were compared between fittings.ResultsReducing the low-pass filter cutoff frequency or adding noise to the speech signal increased VRTs in normal hearing people, suggesting an inverse relationship between VRT and ease of listening. In the hearing-impaired group, VRTs with different fittings of the hearing aid showed differences that can be used as an indicator of listening effort.ConclusionsAdding a measurement of VRT to a regular word recognition test during hearing aid fitting could be useful for adjusting parameters or deciding between models or processing strategies, especially if recognition scores are high.
FACTORS INCREASING THE RISK OF HEARING LOSS AMONG HYPERTENSIVE PATIENTS: A PROSPECTIVE STUDY
Authors: Bener Abdulbari , Barısık Cem , Inan Funda 
Published: October 2022

BackgroundHearing loss and hypertension are leading causes of disability, affecting over 360 million people. The aim of this study was to assess the impacts of factors such as vitamin D and sleep disorder on the risk of hearing loss among hypertensive patients.Material and methodsThis prospective cohort study involved 885 patients aged between 25 and 65 years old who visited our ENT and Endocrinology departments. The study was based on biochemical tests, physical examination, hearing assessment, and Pittsburgh Sleep Quality Index test. Statistical analysis used bivariate and multivariate stepwise regression.ResultsOf 855 hypertensive patients, 184 (21.5%) had hearing loss. There were statistically significant differences between hypertensive patients with and without hearing loss in terms of BMI, smoking, family history of diabetes, tinnitus, vertigo, and headache. Moreover, there were statistically significant differences between hypertensive patients with hearing loss versus those with normal hearing in terms of vitamin D, calcium, magnesium, potassium, fasting glucose, HbA1C, HDL, systolic and diastolic blood pressure, microalbuminuria, and sleep quality. Among hypertensive patients, a multivariate regression analysis (stepwise method) indicated that vertigo, systolic blood pressure, vitamin D deficiency, numbness in the hand, tinnitus, vigorous activity, metabolic syndrome, sleep disturbance, and obesity were all risk predictors of hearing loss.ConclusionsControlling hypertension, vitamin D level, sleep, and lifestyle might lower the risk of hearing loss among hypertensive patients.
QUALITY OF LIFE QUESTIONNAIRE AND FREQUENCY FOLLOWING RESPONSE IN TWO DYSARTHRIC SUBJECTS WITH NEURODEGENERATIVE DISEASE: A CASE STUDY
Authors: Rohers Dara , Mundt Aline , Portalete Caroline , Malavolta Vitor , Moreira Hélinton , Keske-Soares Marcia , Skarzynski Piotr , Sanfins Milaine , Garcia Michele 
Published: October 2022

BackgroundEffective speech production involves a complex system that not only requires planning and motor execution in different speech subsystems, but also depends on the proper functioning of the auditory system. In cases of dysarthria, auditory electrophysiological assessment
can be important, since it can help diagnose the underlying neurological disease. The objective of this pilot study was to assess the effectiveness of the frequency-following response (FFR) in monitoring the progress of speech therapy in cases of dysarthria due to neurodegenerative
disease. It also sought to gauge changes in the patients’ quality of life using a self-report questionnaire.Case reportTwo individuals with dysarthria were assessed by the FFR and by the questionnaire “Living with Dysarthria” while undergoing a speech therapy rehabilitation program aimed at improving their speech. It was found that the speech therapy brought benefits in terms of
quality of life, in line with the FFR responses.ConclusionsThe FFR may be a promising approach to monitoring changes in the central auditory nervous system during speech therapy for dysarthria due to acquired neurodegenerative disease.
More responsibilities to OBJN´s people...
Authors: Zanchetta Margareth Santos 
Published: October 2022

A mais recente expansão de indexação do Online Brazilian Journal of Nursing traz em si um aumento significativo do nosso esforço coletivo para responder continuamente aos critérios de qualidade também de um público leitor internacional. Algumas práticas dos autores internacionais para melhorarem a qualidade de seus manuscritos merecem ser consideradas principalmente pelos autores e revisores do OBJN. Após a preparação do manuscrito, os autores submetem-no a uma leitura crítica pelos leitores/revisores considerados “internos”: um especialista nos aspectos teóricos sobre o tema; um especialista no desenho metodológico da pesquisa, e um terceiro especialista procedente do contexto da prática relativo ao tema do manuscrito. Isto representa a oportunidade de um diálogo científico: eles questionam, criticam e sugerem para ajudar o autor a aumentar suas chances de ter seu manuscrito melhor considerado pelos revisores do periódico para publicação. Tal diálogo e exposição à crítica significa caminhos para o desafio do pensamento científico, revisão de conhecimentos e de posturas filosóficas. Ao autor cabe então usar de humildade acadêmica e abertura de espírito para admitir que o manuscrito submetido pode ser melhorado (e muito!) após tal contribuição não remunerada desses especialistas. Dilema cruel para alguns autores que algumas vezes, por influência da vaidade pessoal, os leva a crer que sua trajetória profissional e titulação acadêmica constituem um selo incontestável da excelência do manuscrito. Aqueles autores que se beneficiam de tal prática da leitura interna comprovam terem elevado suas possibilidades de receberam comentários mais positivos pelos revisores do periódico, após uma segunda ordem de comentários e sugestões.
Effect of Capsular Tension Ring Implantation during Phacoemulsification on Postoperative Refraction
Authors: Belov D. F. , Nikolaenko V. P. 
Published: October 2022

Purpose. To assess refractive result of phacoemulsification (PE) with capsular tension ring (CTR) implantation.Patients and methods. In total, 37 eyes of 37 patients who underwent PE with intraocular lens (IOL) implantation were divided into 2 groups: study group (n = 18) with CTR implantation and control group (n = 19) without CTR. Optical biometry (IOL-Master 500) was performed for each patient before PE. Barrett Universal II Formula was used for IOL calculation. IOL power calculation error was assessed by comparing target refraction and final refraction measured by Topcon-8800 autorefractometer 1 month after surgery.Results. Despite almost identical preoperative values in both groups refractive result was different. Patients with CTR implantation had more hyperopic IOL power calculation error of +0.41 ± 0.52 D versus — 0.02 ± 0.54 D in the control group (p = 0.037). Refractive result in control group was more predictable (mean absolute error was 0.55 ± 0.34 D and 0.41 ± 0.30 D for groups respectively, p = 0.180).Conclusion. CTR implantation could help surgeon to perform PE in complicated cases. Nevertheless, CTR implantation could leads to hyperopic shift. To avoid refractive errors optimized A-constants could be used (118.85 for AcrySof SA60AT and 118.47 for Akreos Adapt AO).
Features of Visual Dysfunctions in Patients with Primary Hypothyroidism and Thyrotoxicosis
Authors: Likhvantseva V. G. , Trubilin V. N. , Korosteleva E. V. , Kapkova S. G. , Vygodin V. A. 
Published: October 2022

Purpose: to study the prevalence and nature of visual dysfunctions in patients with primary hypothyroidism and thyrotoxicosis.Material and methods. The material for this study was the results of a survey of 54 patients (108 eyes) with thyroid dysfunctions: 32 people (64 eyes) with primary untreated hypothyroidism and 22 people (44 eyes) with primary untreated thyrotoxicosis. Static automated perimetry and dedicated shortwave infrared (blue-yellow) perimetry were performed. The average total value of the photosensitivity of each (n = 74) tested point of the field of view was analyzed, the topography of the location of focal defects was studied, and the severity of impairments to photosensitivity was assessed by aggregate signs.Results. Reliably high sensitivity (92.6 %) and specificity (50.0 %) of short-wave infrared perimetry in relation to static automated perimetry were revealed. In thyroid dysfunctions, the prevalence of optic neuropathy reaches 93 % according to the data of short-wave infrared perimetry versus 7 % of static automated perimetry. It is manifested by a diffuse decrease in light sensitivity to blue stimulus with an increase in the depth of depression from the center to the periphery in both types of thyroid dysfunction. Against this background, with primary hypothyroidism, focal defects appeared in the form of first-order scotomas, and with primary thyrotoxicosis, second-order scotomas. Scotomas were located at the periphery of the central visual field, 20–30° from the fixation point. In the analyzed groups, high average group indices of the maximum corrected visual acuity were established, which allows us to speak about the safety of the photopic (cone) component of the visual analyzer.Conclusion. The pattern of photosensitivity disorders, the topography of the location of the loci of local defects revealed by the short-wave infrared perimetry, indicate that the earliest signs of optical neuropathy are manifested at the level of photoreceptors — selectively in the S-cones. Decreased sensitivity to blue stimulus (440 nm) refers to an acquired color anomaly called tritanopia; which can be present with high visual function, is most often associated with a decrease in the number of S-cones and a deficiency of retinol (the source of cyanolab synthesis).
Long-Term Outcomes of Nonadherence to Anti-VEGF Therapy in Advanced Neovascular Age-Related Macular Degeneration
Authors: Kulikov A. N. , Zhalimova V. R. , Maltsev D. S. 
Published: October 2022

Purpose: To study long-term outcomes in neovascular age-related macular degeneration (nAMD) patients with low visual acuity and nonadherence to a treatment regimen of anti-vascular endothelial growth factor (VEGF) therapy.Patients and methods. In this study we included nAMD patients with best corrected visual acuity lower than 0.1 decimal equivalent, nonadherent to anti-VEGF therapy (13 eyes, group I), treatment-naïve (15 eyes, group II) or nonadherence to anti-VEGF therapy followed by termination of anti-VEGF treatment (18 eyes, group III). All participants received comprehensive ophthalmic examination and optical coherence tomography baseline and at the end of the follow-up period.Results: In group I, 7.6 ± 4.3 intravitreal anti-VEGF injections were performed over a mean period of 38.9 ± 27.5 months. In group II, a mean follow-up was 31.7 ± 28.6 months. In group III 4.8 ± 2.2 intravitreal anti-VEGF injections were performed over a mean period of 26.9 ± 26.4 months followed by treatment discontinuation for a mean period of 24.6 ± 18.6 months. None of study groups showed statistically significant changes in BCVA or an increase of central retinal thickness (p > 0.05). At baseline all study eyes frequently demonstrated severe morphological changes in the macula including atrophy of retinal pigment epithelium (RPE), subretinal fibrosis, RPE tear, or giant intraretinal cysts.Conclusion: In nAMD patients with low BCVA and severe anatomical changes in the macula nonadherence to a treatment regimen of anti-VEGF therapy results in non-superior long-term outcomes compared to natural course of the disease.
APACHE II score predicts in-hospital mortality more accurately than inflammatory indices in patients with acute coronary syndrome
Authors: Kahraman Fatih , Yılmaz Ahmet Seyda , Demir Mevlüt , Beşiroğlu Fatih 
Published: October 2022

Aim This study evaluated the prognostic ability of the APACHE II score and compared it with inflammatory indices in patients with acute coronary syndrome (ACS).Material and Methods A total of 525 patients with ACS were retrospectively enrolled in the study. APACHE II scores were calculated and C-reactive protein (CRP), neutrophil-lymphocyte ratio (NLR), and systemic immune-inflammatory index (SII) were recorded. The APACHE II score was compared with inflammatory indices for predicting in-hospital mortality.Results Univariate logistic regression (LR) analysis showed that CRP, SII, NLR, ejection fraction, chronic kidney disease, gender, and APACHE II score were significant predictors of mortality. In multiple LR analysis, the APACHE II score was found to be a solitary, significant predictor of in-hospital mortality (OR: 1.201, 95 % CI: 1.122–1.285; p<0.001). In the Receiver Operating Characteristics curve, using a cut-off point of 16.5, the APACHE II score predicted in-hospital mortality with 70.4 % sensitivity and 92.9 % specificity.Conclusion The APACHE II score may be used as a predictor of in-hospital mortality better than inflammatory markers in ACS patients.
The relationship between pericardial effusion and pulmonary involvement, prognosis, mortality in COVID-19 patients
Authors: Saraç İbrahim , Tonkaz Gökhan , Aksakal Emrah , Aydınyılmaz Faruk , Alişar Kaan , Aydın Sidar Şiyar , Aydemir Selim , Doğan Remziye , Gülcü Oktay , Kalkan Kamuran 
Published: October 2022

Aim Comprehensive studies on the coexistence of COVID-19 and pericardial effusion (PEff) are limited. In this study, we investigated the relationship between pneumonia severity and PEff, predisposing factors, and the effect of PEff on clinical prognosis and mortality in COVID-19 patients.Material and methods Between March and November 2020, 5 575 patients were followed up in our pandemic hospital due to COVID-19. 3 794 patients with positive polymerase chain reaction (PCR) test results and thoraxcomputerized tomography (CT) imaging at admission were included in the study. The clinical and demographic characteristics, CT images, hematological and biochemical parameters of these patients were retrospectively examined. Pulmonary involvement of 3794 patients was divided into three groups and its relationship with PEff was investigated retrospectively.Results There were 560 patients who did not have pulmonary involvement, 2 639 patients with pulmonary involvement below 50 %, and 595 patients with 50 % or more pulmonary involvement. As pulmonaryinvolvement or the severity of the disease increased, male gender and advanced age become statistically significant. The mean age of patients with PEff was higher, and PEff was more common in males. Patients with PEff had more comorbid diseases and significantly elevated serum cardiac and inflammatory biomarkers. The need for intensive care and mortality rates were higher in these patients. While the in-hospital mortality rate was 56.9 % in patients with PEff and pulmonary involvement above 50 %, in-hospital mortality rate was 34.4 % in patients with pulmonary involvement above 50 % and without PEff (p<0.001).The presence of PEff during admission for COVID-19 disease, the appearance of PEff or increase in the degree of PEff during follow-up were closely related to mortality and prognosis.Conclusion As the severity of pulmonary involvement or the clinical severity of the disease increased, PEff occurred in patients or the degree of PEff increased. The clinical prognosis of patients presenting with PEff was quite poor, and the frequency of intensive care admissions and mortality were significantly higher. PEff was an important finding in the follow-up and management of patients with COVID-19, and it reflected the clinical prognosis.
Investigation of the Effects of Fuel Cells on V-Q & V-P Characteristics
Authors: Zadehbagheri Mahmoud , Kiani Mohammad Javad , Sutikno Tole 
Published: October 2022

In this paper, the use of a FC system connected to the network is proposed as a source of DG with high reliability, and for this purpose, the dynamic model of the fuel cell has been simulated. A hybrid system of fuel cell distributed generation (FCDG) is presented to provide electrical energy for a small isolated area. Boost converter (DC/DC), in order to increase the voltage level of the system and stabilize the DC link voltage has been used, which provides the possibility of connecting several different scattered production sources in parallel. Voltage stability is concerned with the ability of a power system to maintain acceptable bus voltages under normal conditions and after being subjected to a disturbance. The use of DG sources has many advantages, including meeting peak load needs, reducing network losses, providing reactive power locally, and regulating network voltage. Among all sources of distributed production, fuel cells are of special importance due to their high efficiency, high energy density, the ability to simultaneously produce heat and electric power, and low emission of pollutants. Using fuel cells (FCs) have several advantages and in this paper we investigate the effects of FCs on power systems via simulation a single machine (DG as small gas turbine coupled with a FC) in the Dig Silent area for different PF of FC. Different PF for FC obtained with control the DC to AC inverter. We found that by control the PF of FCs, we can increase the limitation of reactive generation of overall system and improve the V-P V-Q characteristics of overall system. With the grid-connected inverter's switching control, the active and reactive power injected into the grid is controlled independently.