bluuebunny/crossref_metadata_2025_split huggingface dataset:
Short-chain fatty acids–microbiota crosstalk in the coronavirus disease (COVID-19)
Authors: Włodarczyk Jakub , Czerwiński Bartłomiej , Fichna Jakub 
Published: September 2022

AbstractThe novel coronavirus disease (COVID-19) still remains a major challenge to the health-care systems worldwide, inciting ongoing search for pharmaceutical and non-pharmaceutical interventions which could benefit patients already infected with SARS-CoV-2 or at increased risk thereof. Although SARS-CoV-2 primarily affects the respiratory system, it may also infect other organs and systems, including gastrointestinal tract, where it results in microbial dysbiosis. There is an emerging understanding of the role the gut microbiota plays in maintaining immune homeostasis, both inside the gastrointestinal tract and beyond (i.e. through gut–lung and gut–brain axes). One family of compounds with recognized immunomodulatory and anti-inflammatory properties are short chain fatty acids (SCFAs). SCFAs are believed that they have a protective effect in case of gastrointestinal diseases. Moreover, they are responsible for maintaining proper intestinal barrier and they take part in relevant immune functions. This review presents mechanisms of action and potential benefits of SCFA-based probiotics and direct SCFA supplementation as a strategy to support immune function amid the COVID-19 pandemic.
Radical substance-free phonology and feature learning
Authors: Odden David 
Published: September 2022

AbstractThis article argues that phonological features have no substantive properties, instead, segments are assigned features by learning strategies set to the task of devising a computational system for a phonology that is consistent with the requirements of UG. I address two problems for such a substance-free model. The first is the Card-Grammar problem, which has been suggested to argue for universal substantive features, on the premise that, otherwise, language data cannot be stored in a fashion necessary to correct learning errors. The Card Grammar problem disappears, in a suitably modular theory of mind with learned interfaces, where the mind still can retain information not parsed in a particular grammar. The second problem is the need for a demonstration, not just an assertion, that a reasonable theory of grammar and learning which has no access to phonetic substance can yield a coherent system of feature assignments. This is accomplished by modeling the learning of features necessary for the phonology of Kerewe.
How best to improve upon return-to-player information in gambling? A comparison of two approaches in an Australian sample
Authors: Newall Philip W. S. , Walasek Lukasz , Ludvig Elliot A. 
Published: September 2022

Abstract
“Return-to-player” information is used in several jurisdictions to display the long-run cost of gambling, but previous evidence suggests that these messages are frequently misunderstood by gamblers. Two ways of improving the communication of return-to-player information have been suggested: switching to an equivalent “house-edge” format, or via the use of a “volatility warning,” clarifying that the information applies only in the statistical long run. In this study, Australian participants (N = 603) were presented with either a standard return-to-player message, the same message supplemented with a volatility warning, or a house-edge message. The return-to-player plus volatility warning message was understood correctly more frequently than the return-to-player message, but the house-edge message was understood best of all. Participants perceived the lowest chance of winning in the return-to-player plus volatility warning condition. These findings contribute data on the relative merits of two proposed approaches in the design of improved gambling information.
Lost in Translation? The Promises and Challenges of Integrating Empirical Knowledge on Migrants’ Vulnerabilities into Legal Reasoning
Authors: Leboeuf Luc 
Published: September 2022

AbstractThe concept of “vulnerability” has become all-pervasive in EU asylum law and the ECtHR case law on asylum seekers and migrants, where it has acquired various legal meanings and functions. But many controversies remain on the legal nature, definition, and consequences of “vulnerability.” Based on lessons learned in the process of establishing the overall research design of the Horizon 2020 VULNER project and coordinating its implementation, this article identifies the contribution that anthropological knowledge can bring to ongoing legal debates and reflects on the conceptual and practical challenges that emerge when engaging in such an endeavor.First, the article shows the potential of anthropological research methods and concepts to shed light on the experiences of vulnerability as they are lived by migrants, and to reveal and question the underlying social and political dynamics behind the increased success of vulnerability in legal reasoning. Second, it argues that anthropology can only bring a useful contribution to legal debates on “vulnerability” if the knowledge it produces is adequately translated into legal reasoning—which requires acknowledging the differences between the goals of anthropological analyses, which are all-encompassing and seek to depict human experiences in all their complexities, and legal conceptualizations, which require establishing clearly defined notions that can be operationalized in—relatively—certain ways by decision-makers on the ground and that allow them to strike a balance between competing interests.
“To Leave Is to Die”: States’ Use of Mobility in Anticipation of Land Uninhabitability
Authors: Courtoy Marie 
Published: September 2022

AbstractClimate change is profoundly modifying the earth’s environment, making certain territories uninhabitable. Faced with this known phenomenon, this article outlines a research approach for assessing the law’s role in encouraging states to preemptively protect individuals who live in deteriorating territories, notably by enabling mobility. The question is, however, far from simple, insofar as most of the ways to adapt to climate change—and particularly mobility, which has important human and social implications—require profound societal choices that anthropology has the tools to study. I therefore accompany my legal research with an anthropological approach centered around ethnography conducted at three sites—France, Guadeloupe, Senegal—where state-sponsored mobility is either being considered or already being used as an option to confront the progressive disappearance of land that is being swept away by the sea.
Adequate vitamin B12 and folate status of Norwegian vegans and vegetarians
Authors: Henjum Sigrun , Groufh-Jacobsen Synne , Lindsay Allen , Raael Ellen , Israelsson Anna Maria , Shahab-Ferdows Setareh , Hampel Daniela 
Published: September 2022

AbstractPlant-based diets may increase the risk of vitamin B12 deficiency due to limited intake of animal-source foods, while dietary folate increases when adhering to plant-based diets. In this cross-sectional study, we evaluated the B12 and folate status of Norwegian vegans and vegetarians using dietary B12 intake, B12 and folic acid supplement use, and biomarkers (serum B12 (B12), plasma total homocysteine (tHcy), plasma methylmalonic acid (MMA) and serum folate). Vegans (n 115) and vegetarians (n 90) completed a 24-h dietary recall and a FFQ and provided a non-fasting blood sample. cB12, a combined indicator for evaluation of B12 status, was calculated. B12 status was adequate in both vegans and vegetarians according to the cB12 indicator; however 4 % had elevated B12. Serum B12, tHcy, MMA concentrations and the cB12 indicator (overall median: 357 pmol/l, 9·0 µmol/l, 0·18 µmol/l, 1·30 (cB12)) did not differ between vegans and vegetarians, unlike for folate (vegans: 25·8 nmol/l, vegetarians: 21·6 nmol/l, P = 0·027). Serum B12 concentration < 221 pmol/l was found in 14 % of all participants. Vegetarians revealed the highest proportion of participants below the recommended daily intake of 2 µg/d including supplements (40 v. 18 %, P < 0·001). Predictors of higher serum B12 concentrations were average daily supplement use and older age. Folate deficiency (< 10 nmol/l) was uncommon overall (< 2·5 %). The combined indicator cB12 suggested that none of the participants was B12-depleted; however, low serum B12 concentration was found in 14 % of the participants. Folate concentrations were adequate, indicating adequate folate intake in Norwegian vegans and vegetarians.
CHANGING THE SAIL: PROPERTIUS 3.21, CATULLUS 64 AND OVID, HEROIDES 5
Authors: Westwood Guy 
Published: September 2022

AbstractConcentrating on Propertius 3.21 in particular, this article identifies a previously unnoticed network of allusions by three Roman poets (Catullus, Propertius and Ovid) to one another and to Book 1 of Apollonius Rhodius’ Argonautica. It shows that these intertextual links are pivoted on the three poets’ common use of the verse-ending lintea malo in scenes of departure by sea, and on their common interest in framing other aspects of the nautical context (especially the naval equipment involved and the presence of a favourable wind) in specific ways. Highlighting the presence in all three cases of departing male lovers with traditionally compromised or otherwise dubious claims to heroism, the article argues that each of the three instances shows the poet in question interacting competitively and self-consciously with the usages of his predecessor(s) (and with those usages’ immediate contexts) and exploiting the choices made by them to serve his new context and to advertise his personal skill in the creative deployment of revered poetic models.
Primate conservation in the Arc of Deforestation: a case study of Vieira's titi monkey Plecturocebus vieirai
Authors: Costa-Araújo Rodrigo , da Silva Lucas Gonçalves , de Melo Fabiano Rodrigues , Rossi Rogério Vieira , Bottan João Pedro , Silva Diego Afonso , Oliveira do Nascimento Fabio , da Silva Felipe Pessoa , Buss Gerson , Lima-Silva Luan Gabriel , da Silva Luciano Ferreira , Fialho Marcos , de Lázari Patrick Ricardo , Rossato Rafael Suertegaray , Vendramel Rafaela Lumi , de Mendonça Ravena Fernanda Braga , Sampaio Ricardo , Hrbek Tomas , Alencar Raony Macedo de , Junior José de Sousa e Silva , Canale Gustavo Rodrigues 
Published: September 2022

AbstractFifty years of deforestation in the Arc of Deforestation have put at risk species survival, ecosystem services and the stability of biogeochemical cycles in Amazonia, with global repercussions. In response, we need to understand the diversity, distribution and abundance of flagship species groups, such as primates, which can serve as umbrella species for broad biodiversity conservation strategies and help mitigate climate change. Here we identify the range, suitable habitat areas and population size of Vieira's titi monkey Plecturocebus vieirai and use it as an emblematic example to discuss biodiversity conservation and climate change mitigation in one of the largest deforestation frontiers. Our findings show that deforestation for agriculture and cattle-ranching expansion is the major threat to P. vieirai and is responsible for present (56%) and projected (14%) reductions in habitat area and population size. We also found that human-driven climate change affects the P. vieirai niche negatively, triggering habitat degradation and further population decline even inside protected areas. Primate watching can be a profitable alternative to forest exploitation on private, public or Indigenous lands in the Arc of Deforestation and is a way to shift the traditional, predatory extraction of natural resources from Amazonia towards sustainable land use based on biodiversity conservation at local, regional and global scales, local people's welfare and climate change mitigation. New models of land use and income generation are required to protect the unique natural and human heritages of the Arc of Deforestation and the life-supporting ecosystem services and products provided by Amazonia.
Modulation of resting-state functional connectivity in default mode network is associated with the long-term treatment outcome in major depressive disorder
Authors: Ju Yumeng , Wang Mi , Liu Jin , Liu Bangshan , Yan Danfeng , Lu Xiaowen , Sun Jinrong , Dong Qiangli , Zhang Liang , Guo Hua , Zhao Futao , Liao Mei , Zhang Li , Zhang Yan , Li Lingjiang 
Published: September 2022

AbstractBackgroundTreatment non-response and recurrence are the main sources of disease burden in major depressive disorder (MDD). However, little is known about its neurobiological mechanism concerning the brain network changes accompanying pharmacotherapy. The present study investigated the changes in the intrinsic brain networks during 6-month antidepressant treatment phase associated with the treatment response and recurrence in MDD.MethodsResting-state functional magnetic resonance imaging was acquired from untreated patients with MDD and healthy controls at baseline. The patients' depressive symptoms were monitored by using the Hamilton Rating Scale for Depression (HAMD). After 6 months of antidepressant treatment, patients were re-scanned and followed up every 6 months over 2 years. Traditional statistical analysis as well as machine learning approaches were conducted to investigate the longitudinal changes in macro-scale resting-state functional network connectivity (rsFNC) strength and micro-scale resting-state functional connectivity (rsFC) associated with long-term treatment outcome in MDD.ResultsRepeated measures of the general linear model demonstrated a significant difference in the default mode network (DMN) rsFNC change before and after the 6-month antidepressant treatment between remitters and non-remitters. The difference in the rsFNC change over the 6-month antidepressant treatment between recurring and stable MDD was also specific to DMN. Machine learning analysis results revealed that only the DMN rsFC change successfully distinguished non-remitters from the remitters at 6 months and recurring from stable MDD during the 2-year follow-up.ConclusionOur findings demonstrated that the intrinsic DMN connectivity could be a unique and important target for treatment and recurrence prevention in MDD.
Glial cell response to constant low light exposure in rat retina
Authors: Bruera Manuel G. , Benedetto María M. , Guido Mario E. , Degano Alicia L. , Contin María A. 
Published: September 2022

Abstract
To study the macroglia and microglia and the immune role in long-time light exposure in rat eyes, we performed glial cell characterization along the time-course of retinal degeneration induced by chronic exposure to low-intensity light. Animals were exposed to light for periods of 2, 4, 6, or 8 days, and the retinal glial response was evaluated by immunohistochemistry, western blot and real-time reverse transcription polymerase chain reaction. Retinal cells presented an increased expression of the macroglia marker GFAP, as well as increased mRNA levels of microglia markers Iba1 and CD68 after 6 days. Also, at this time-point, we found a higher number of Iba1-positive cells in the outer nuclear layer area; moreover, these cells showed the characteristic activated-microglia morphology. The expression levels of immune mediators TNF, IL-6, and chemokines CX3CR1 and CCL2 were also significantly increased after 6 days. All the events of glial activation occurred after 5–6 days of constant light exposure, when the number of photoreceptor cells has already decreased significantly. Herein, we demonstrated that glial and immune activation are secondary to neurodegeneration; in this scenario, our results suggest that photoreceptor death is an early event that occurs independently of glial-derived immune responses.
“It just never ends”: Childhood cancer survivors’ perceived psychosocial impacts of recurrence and second cancer
Authors: Lee Andrea E. , McLoone Jordana K. , Touyz Lauren M. , Wakefield Claire E. , Cohn Richard J. , Signorelli Christina 
Published: September 2022

AbstractObjectivesChildhood cancer survivors are at risk of developing primary recurrences and new second cancers. Experiencing a recurrence and/or second cancer can be highly distressing for survivors and families. We aimed to understand the psychological impacts of experiencing a recurrence or second cancer and how this potentially influences survivors’ engagement with survivorship care.MethodsWe invited childhood cancer survivors or their parents if survivors were ≤16 years of age from 11 tertiary pediatric oncology hospitals across Australia and New Zealand to complete interviews. We conducted a thematic analysis facilitated by NVivo12.ResultsWe interviewed 21 participants of whom 16 had experienced a recurrence, 3 had a second cancer, and 2 had both a recurrence and second cancer. Participants reported that a recurrence/second cancer was a stressful sudden disruption to life, accompanied by strong feelings of uncertainty. Participants tended to be less aware of their second cancer risk than recurrence risk. Some participants reported feelings of anxiousness and despair, describing varying responses such as gratitude or avoidance. Participants shared that the fear of cancer recurrence either motivated them to adopt protective health behaviors or to avoid information and disengage from survivorship care.Significance of resultsSome survivors and their parents have a poor understanding and expressed reluctance to receive information about their risk of second cancer and other treatment-related late effects. Improving the delivery of information about late effects to families may improve their engagement with survivorship care and surveillance, although care must be taken to balance information provision and survivors’ anxieties about their future health.
Women’s Support Shaken: A Study of Women’s Political Trust after Natural Disasters
Authors: Kreutzer Willow 
Published: September 2022

AbstractWomen have unique experiences during natural disasters, including higher risks of death, violence, and socioeconomic decline and an increase in specific reproductive health needs. However, government responses often do not directly address these women-specific needs, which can decrease women’s political trust. I investigate women’s trust in government institutions when natural disasters have recently occurred and argue that because of their unique experiences and typical government responses, women’s political trust will decline when there is a natural disaster more than men’s. I find that when there is a high number of disasters and when a larger percentage of the population is affected by disasters, women’s political trust decreases significantly, especially institutional trust. These findings are distinct from previous studies that cluster different types of political trust and support the idea that women’s experiences in a disaster may influence their relationship with institutions differently than men’s.
Spatial Distribution and Physicochemical Properties of Respirable Volcanic Ash From the 16–17 August 2006 Tungurahua Eruption (Ecuador), and Alveolar Epithelium Response In‐Vitro
Authors: Eychenne Julia , Gurioli Lucia , Damby David , Belville Corinne , Schiavi Federica , Marceau Geoffroy , Szczepaniak Claire , Blavignac Christelle , Laumonier Mickael , Gardés Emmanuel , Le Pennec Jean‐Luc , Nedelec Jean‐Marie , Blanchon Loïc , Sapin Vincent 
Published: September 2022

AbstractTungurahua volcano (Ecuador) intermittently emitted ash between 1999 and 2016, enduringly affecting the surrounding rural area and its population, but its health impact remains poorly documented. We aim to assess the respiratory health hazard posed by the 16–17 August 2006 most intense eruptive phase of Tungurahua. We mapped the spatial distribution of the health‐relevant ash size fractions produced by the eruption in the area impacted by ash fallout. We quantified the mineralogy, composition, surface texture, and morphology of a respirable ash sample isolated by aerodynamic separation. We then assessed the cytotoxicity and pro‐inflammatory potential of this respirable ash toward lung tissues in‐vitro using A549 alveolar epithelial cells, by electron microscopy and biochemical assays. The eruption produced a high amount of inhalable and respirable ash (12.0–0.04 kg/m2 of sub‐10 μm and 5.3–0.02 kg/m2 of sub‐4 μm ash deposited). Their abundance and proportion vary greatly across the deposit within the first 20 km from the volcano. The respirable ash is characteristic of an andesitic magma and no crystalline silica is detected. Morphological features and surface textures are complex and highly variable, with few fibers observed. In‐vitro experiments show that respirable volcanic ash is internalized by A549 cells and processed in the endosomal pathway, causing little cell damage, but resulting in changes in cell morphology and membrane texture. The ash triggers a weak pro‐inflammatory response. These data provide the first understanding of the respirable ash hazard near Tungurahua and the extent to which it varies spatially in a fallout deposit.
2D Reconstruction of Magnetotail Electron Diffusion Region Measured by MMS
Authors: Schroeder J. M. , Egedal J. , Cozzani G. , Khotyaintsev Yu. V. , Daughton W. , Denton R. E. , Burch J. L. 
Published: September 2022

AbstractModels for collisionless magnetic reconnection in near‐Earth space are distinctly characterized as 2D or 3D. In 2D kinetic models, the frozen‐in law for the electron fluid is usually broken by laminar dynamics involving structures set by the electron orbit size, while in 3D models the width of the electron diffusion region is broadened by turbulent effects. We present an analysis of in situ spacecraft observations from the Earth's magnetotail of a fortuitous encounter with an active reconnection region, mapping the observations onto a 2D spatial domain. While the event likely was perturbed by low‐frequency 3D dynamics, the structure of the electron diffusion region remains consistent with results from a 2D kinetic simulation. As such, the event represents a unique validation of 2D kinetic, and laminar reconnection models.
Stratospheric Balloon Observations of Infrasound Waves From the 15 January 2022 Hunga Eruption, Tonga
Authors: Podglajen Aurélien , Le Pichon Alexis , Garcia Raphaël F. , Gérier Solène , Millet Christophe , Bedka Kristopher , Khlopenkov Konstantin , Khaykin Sergey , Hertzog Albert 
Published: September 2022

AbstractThe 15 January 2022 eruption of the Hunga volcano (Tonga) generated a rich spectrum of waves, some of which achieved global propagation. Among numerous platforms monitoring the event, two stratospheric balloons flying over the tropical Pacific provided unique observations of infrasonic wave arrivals, detecting five complete revolutions. Combined with ground measurements from the infrasound network of the International Monitoring System, balloon‐borne observations may provide additional constraint on the scenario of the eruption, as suggested by the correlation between bursts of acoustic wave emission and peaks of maximum volcanic plume top height. Balloon records also highlight previously unobserved long‐range propagation of infrasound modes and their dispersion patterns. A comparison between ground‐ and balloon‐based measurements emphasizes superior signal‐to‐noise ratios onboard the balloons and further demonstrates their potential for infrasound studies.