bluuebunny/crossref_metadata_2025_split huggingface dataset:
Insufficient Evidence for Multiple Species of Tyrannosaurus in the Latest Cretaceous of North America: A Comment on “The Tyrant Lizard King, Queen and Emperor: Multiple Lines of Morphological and Stratigraphic Evidence Support Subtle Evolution and Probable Speciation Within the North American Genus Tyrannosaurus”
Authors: Carr Thomas D. , Napoli James G. , Brusatte Stephen L. , Holtz Thomas R. , Hone David W. E. , Williamson Thomas E. , Zanno Lindsay E. 
Published: July 2022

AbstractThe Late Cretaceous dinosaur Tyrannosaurus rex was recently split into three species based on the premise that variation in the T. rex hypodigm is exceptional, indicating cryptic species and “robust” and “gracile” morphs. The morphs are based on proportional ratios throughout the skeleton. The species are claimed to be stratigraphically separate, with an early robust species followed by robust and gracile descendants. There are problems with the hypothesis: the taxon diagnoses are based on two features that overlap between the species; several skulls cannot be identified based on the diagnoses; proportional comparisons between Tyrannosaurus and other theropods are based on incomparable samples; the tooth data are problematic; the stratigraphic framework divides the Hell Creek Formation into thirds, without the stratigraphic position of each specimen, or independent age control showing the subdivisions are coeval over the entire geographic area; previous work found variation in T. rex, but it cannot be parsed into discrete categories. We tested for “gracile” and “robust” morphs by analyzing the femoral and tooth ratios that were published in the multiple species study using agglomerative hierarchical clustering. The results found that each set of ratios are explained by one cluster, showing that dimorphism is not supported. We tested for exceptional variation of the femoral ratio of Tyrannosaurus; we calculated the mean intraspecific robusticity for 112 species of living birds and 4 nonavian theropods. The results showed that the absolute variation in Tyrannosaurus is unexceptional and it does not indicate cryptic diversity. We conclude that “T. regina” and “T. imperator” are subjective junior synonyms of T. rex.
Change of Heart: the Epitranscriptome of Small Non-coding RNAs in Heart Failure
Authors: Woudenberg Tamar , Kruyt Nyika D. , Quax Paul H. A. , Nossent A. Yaël 
Published: July 2022

Abstract
Purpose of Review
Small non-coding RNAs regulate gene expression and are highly implicated in heart failure. Recently, an additional level of post-transcriptional regulation has been identified, referred to as the epitranscriptome, which encompasses the body of post-transcriptional modifications that are placed on RNA molecules. In this review, we summarize the current knowledge on the small non-coding RNA epitranscriptome in heart failure.

Recent Findings
With the rise of new methods to study RNA modifications, epitranscriptome research has begun to take flight. Over the past 3 years, the number of publications on the epitranscriptome in heart failure has significantly increased, and we expect many more highly relevant publications to come out over the next few years.

Summary
Currently, at least six modifications on small non-coding RNAs have been investigated in heart failure-relevant studies, namely N6-adenosine, N5-cytosine and N7-guanosine methylation, 2’-O-ribose-methylation, adenosine-to-inosine editing, and isomiRs. Their potential role in heart failure is discussed.
Association of Kidney Stones and Recurrent UTIs: the Chicken and Egg Situation. A Systematic Review of Literature
Authors: Ripa Francesco , Pietropaolo Amelia , Montanari Emanuele , Hameed B. M. Zeeshan , Gauhar Vineet , Somani Bhaskar K. 
Published: July 2022

Abstract
Purpose of Review
Kidney stone disease (KSD) and recurrent urinary tract infections (rUTI) are frequently concomitant conditions. We conducted a systematic review to determine the association of UTI in patients with KSD and to assess the outcomes of kidney stone treatment in the resolution of rUTI.

Recent Findings
Our systematic review included 17 papers and a strong association between KSD and rUTI was demonstrated by numerous studies. Surgical clearance of kidney stones usually resulted in the resolution of UTI, but discordant data persist regarding recurrence rates after surgery. In vitro studies might unveil the causative role of bacteria in the formation of “metabolic” stones.

Summary
Our SR clearly shows that UTI and KSD are mutually coexisting, and reciprocally causal and such patients should be counselled for proactive intervention by stone removal especially when UTIs are recurrent or additional risk factors are present irrespective of stone composition. To prevent further UTI episodes, if possible, a stone culture must be obtained for an effectively targeted antibiotic treatment regime tailored to bacterial prevalence.
A Mind-inspired Architecture for Adaptive HRI
Authors: Umbrico Alessandro , De Benedictis Riccardo , Fracasso Francesca , Cesta Amedeo , Orlandini Andrea , Cortellessa Gabriella 
Published: July 2022

AbstractOne of the main challenges of social robots concerns the ability to guarantee robust, contextualized and intelligent behavior capable of supporting continuous and personalized interaction with different users over time. This implies that robot behaviors should consider the specificity of a person (e.g., personality, preferences, assistive needs), the social context as well as the dynamics of the interaction. Ideally, robots should have a “mind" to properly interact in real social environments allowing them to continuously adapt and exhibit engaging behaviors. The authors’ long-term research goal is to create an advanced mind-inspired system capable of supporting multiple assistance scenarios fostering personalization of robot’s behavior. This article introduces the idea of a dual process-inspired cognitive architecture that integrates two reasoning layers working on different time scales and making decisions over different temporal horizons. The general goal is also to support an empathetic relationship with the user through a multi-modal interaction inclusive of verbal and non-verbal expressions based on the emotional-cognitive profile of the person. The architecture is exemplified on a cognitive stimulation domain where some experiments show personalization capabilities of the approach as well as the joint work of the two layers. In particular, a feasibility assessment shows the customization of robot behaviors and the adaptation of robot interactions to the online detected state of a user. Usability sessions were performed in laboratory settings involving 10 healthy participants to assess the user interaction and the robot’s dialogue performance.
Crafting the success and failure of decentralized marine management
Authors: Wencélius Jean , Lauer Matthew , Bambridge Tamatoa 
Published: July 2022

AbstractThis paper presents an ethnographic case study of the design and revision of a decentralized marine management scheme implemented on the island of Moorea, French Polynesia named Plan de Gestion de l’Espace Maritime (PGEM). Drawing on an analysis of over 50 consultative workshops and meetings, held from 2018 to 2021 during the PGEM revision, we document the materials, discourses, and practices local stakeholders (e.g., fishers, cultural and environmental activists, government staff, and scientists) combine to build their interpretations of PGEM success or failure. We examine the diversity of domains these interpretations draw from (ecology, marine livelihoods, culture, religion, and politics) and how they are put into practice in people’s engagement with—or resistance to—the local marine management and governance design. Our results highlight how the controversies around the revision of Moorea’s PGEM overflowed the boundaries of ecology as construed by scientific experts. Stakeholders interpreted “marine resource management” as something well beyond just “marine resources” to include politics, identity, Polynesian cosmology, and livelihoods. Our findings provide generalizable patterns for understanding how natural-resource management policies are received and repurposed by local actors.
Investigating causes and risk factors of pre-chemotherapy viremia in acute lymphoblastic leukemia pediatric patients
Authors: Abdel-azim Nivin , Alkilany Lamiaa Fadel , Hassan Zeinab Korany , Gaber Noha 
Published: July 2022

Abstract
Background
Leukemia patients are immune-compromised even before starting chemotherapy because the malignant cells invade the bone marrow and destroy WBC precursors. Leukemic patients are more susceptible to infection by a wide range of microorganisms. Viral infections and reactivations are common and may result in severe complications. The aim of this study is to investigate different causes of viremia in ALL pediatric patients as well as the clinical and the laboratory characteristics associated with viral infections.

Methods
Qualitative real-time PCR was used to detect (polyoma BK, parvo B19 and herpes simplex virus) DNA in the blood of ALL patients and routine hospital records were used to provide the data of hepatitis B & C virus infection.

Results
Polyoma BK was the most common detected virus (51.2%) followed by herpes simplex (30.2%). Viremia by single virus was found in 16 (37.2%) cases, while viremia by multiple viruses was found in 15 (34.8%) cases. The most frequent co-detected viruses were herpes simplex and polyoma BK (11.6%) followed by herpes simplex, parvo B19 and polyoma BK (9.3%).

Conclusion
There is a high frequency of viremia by single virus and viremia by multiple viruses at the time of diagnosis of acute lymphoblastic leukemia in pediatric patients admitted to South Egypt Cancer Institute (SECI) compared to studies in other regions. Polyoma BK is the most common detected virus and is mainly associated with lymphopenia. It was also significantly associated with herpes simplex viremia. HCV infection was associated with increased incidence of CNS leukemia.
Scorched Earth: Discourses of Multiplanetarity, Climate Change, and Martian Terraforming in Finch and Once Upon a Time I Lived on Mars.
Authors: Temmen Jens 
Published: July 2022

AbstractThis contribution discusses the current surge of Mars colonization narratives both in science and culture, and the ways these narratives are received and circulated in current ecocritical debates on a multiplanetary future of humanity. This analysis in this contribution takes its cue from the representation of the California wildfires of 2020 as an anthropogenic spectacle that is foreboding of a post-apocalyptic future in which Earth becomes Mars-like, and discusses how this discourse is reproduced in the Hollywood movieFinchand Kate Greene’s popular science memoirOnce Upon A Time I Lived on Mars. As texts of quasi-science communication, they produce a contact zone between Earth/Mars which serves to legitimize technoliberal fantasies of terraforming Mars into Earth as a solution to climate change. With all paths to all possible futures of human habitation – utopian or dystopian – allegedly leading right through the Red Planet, there is an urgency to critically engage with the idea of planetarity being overwritten by a discourse of multiplanetarity that veils the continuity of extractivist capitalism/colonialism in a narrative of futurity and progress.
Materials and Places for Learning: Experiences of Doctoral Students in and around University Spaces
Authors: Carvalho Lucila , Freeman Cristina Garduño 
Published: July 2022

Abstract
People are more likely to thrive when they feel connected, when they feel they belong to a group, to a place, or when they feel part of a community. Places can play a powerful role in shaping one’s attachment to others and to institutions as part of the development of one’s identity. People’s experiences of places are linked to their sensorial impressions of material and digital elements, and to their perceptions of how multiple elements interconnect and impact lived experiences or imagined futures. This research investigates doctoral students’ experiences of places for learning in and around a university in New Zealand. The analysis combines individual interviews and digital multimodal artefacts created by participants who were studying on campus or studying at distance and remotely located. By acknowledging the diversity of university spaces where learning activity may unfold — in classrooms, at libraries, in the canteen, in the corridors, via online learning management systems, social media and messaging, or in the many in-between spaces such as buses, cafes, or working from home — this paper discusses the connections between people, places, material, and digital artefacts, with a focus on the materiality of learning in and around university spaces. Using socio-material conceptual lenses, the article reveals how students navigate the postdigital university through the spaces they inhabit and the places they value, and how their attachment to materials, feelings of inclusion, and learning purpose interconnect to support their (emerging) professional identity.
Oral antiviral treatments for COVID-19: opportunities and challenges
Authors: Rahmah Laila , Abarikwu Sunny O. , Arero Amanuel Godana , Essouma Mickael , Jibril Aliyu Tijani , Fal Andrzej , Flisiak Robert , Makuku Rangarirai , Marquez Leander , Mohamed Kawthar , Ndow Lamin , Zarębska-Michaluk Dorota , Rezaei Nima , Rzymski Piotr 
Published: July 2022

AbstractThe use of antiviral COVID-19 medications can successfully inhibit SARS-CoV-2 replication and prevent disease progression to a more severe form. However, the timing of antiviral treatment plays a crucial role in this regard. Oral antiviral drugs provide an opportunity to manage SARS-CoV-2 infection without a need for hospital admission, easing the general burden that COVID-19 can have on the healthcare system. This review paper (i) presents the potential pharmaceutical antiviral targets, including various host-based targets and viral-based targets, (ii) characterizes the first-generation anti-SARS-CoV-2 oral drugs (nirmatrelvir/ritonavir and molnupiravir), (iii) summarizes the clinical progress of other oral antivirals for use in COVID-19, (iv) discusses ethical issues in such clinical trials and (v) presents challenges associated with the use of oral antivirals in clinical practice. Oral COVID-19 antivirals represent a part of the strategy to adapt to long-term co-existence with SARS-CoV-2 in a manner that prevents healthcare from being overwhelmed. It is pivotal to ensure equal and fair global access to the currently available oral antivirals and those authorized in the future.
Chemical looping reforming: process fundamentals and oxygen carriers
Authors: Zheng Hao , Jiang Xiaofeng , Gao Yanxiu , Tong Andrew , Zeng Liang 
Published: July 2022

AbstractChemical looping reforming (CLR) provides a viable process intensification approach for clean and efficient syngas production from carbonaceous fuel with inherent gas–gas separation. The rational design of metal oxide-based oxygen carriers and the scale-up of associated CLR reactor systems play important roles in CLR process development. This review first introduces the concept and advantages of CLR as well as its historical development. The process fundamentals, including basic schemes, reaction stoichiometry, thermodynamics, kinetics and reactor system design, are reviewed. The integral approach for CLR process development is illustrated, showing that the design and compatibility of oxygen carriers and reactor systems are critical for CLR performance. The reaction principle during the reduction of oxygen carriers is discussed, followed by strategies for improving the redox reactivity and stability. We further review and discuss the latest exciting advances on this subject with the purpose of illustrating factors that govern fundamental mechanisms in the redox reaction chemistry of oxygen carriers and their design principles for sustained chemical looping reactor applications. It is expected that these new advances will inspire more effective oxygen carriers and efficient reactor systems for the development and deployment of various CLR processes.
Regulated deficit irrigation: an effective way to solve the shortage of agricultural water for horticulture
Authors: Yang Bohan , Fu Peining , Lu Jiang , Ma Fengwang , Sun Xiangyu , Fang Yulin 
Published: July 2022

AbstractThe deficient agricultural water caused by water shortage is a crucial limiting factor of horticultural production. Among many agricultural water-saving technologies, regulated deficit irrigation (RDI) has been proven to be one of the effective technologies to improve water use efficiency and reduce water waste on the premise of maintaining the quality of agricultural products. RDI was first reported more than 40 years ago, although it has been applied in some areas, little is known about understanding of the implementation method, scope of application and detailed mechanism of RDI, resulting in the failure to achieve the effect that RDI should have. This review refers to the research on RDI in different crops published in recent years, summarizes the definition, equipment condition, function, theory illumination, plant response and application in different crops of RDI, and looks forward to its prospect. We expect that this review will provide valuable guidance for researchers and producers concerned, and support the promotion of RDI in more horticultural crops.
Computational co-design of fibrous architecture
Authors: Menges Achim , Kannenberg Fabian , Zechmeister Christoph 
Published: July 2022

AbstractFibrous architecture constitutes an alternative approach to conventional building systems and established construction methods. It shows the potential to converge architectural concerns such as spatial expression and structural elegance, with urgently required resource effectiveness and material efficiency, in a genuinely computational approach. Fundamental characteristics of fibre composite are shared with fibre structures in the natural world, enabling the transfer of design principles and providing a vast repertoire of inspiration. Robotic fabrication based on coreless filament winding, a technique to deposit resin impregnated fibre filaments with only minimal formwork, as well as integrative computational design methods are imperative to the development of complex fibrous building systems. Two projects, the BUGA Fibre Pavilion as an example for long-span structures, and Maison Fibre as an example of multi-storey architecture, showcase the application of those techniques in an architectural context and highlight areas of further research opportunities. The highly interrelated aesthetic, structural and fabrication characteristics of fibre nets are difficult to understand and go beyond a designer’s comprehension and intuition. An AI powered, self-learning agent system aims to extend and thoroughly explore the design space of fibre structures to unlock the full design potential coreless filament winding offers. In order to ensure feedback between all relevant design and performance criteria and enable interdisciplinary convergence, these novel design methods are embedded in a larger co-design framework. It formalizes the interaction of involved interdisciplinary domains and allows for interactive collaboration based on a central data model, serving as a base for design optimisation and exploration. To further advance research on fibre composites in architecture, bio-based materials are considered, continuing the journey of discovery of fibrous architecture to fundamentally rethinking design and construction towards a novel, computational material culture in architecture.
“New Private Law Theory” as a Mosaic: What Can Hold (Most of) It Together?
Authors: Dagan Hanoch 
Published: July 2022

AbstractStefan Grundmann, Hans Micklitz, and Moritz Renner’s New Private Law Theory: A Pluralist Approach is a wide-ranging, ambitious, and fascinating project. In this article I offer one way to read the NPLT as a mosaic, rather than a patchwork, by first taking seriously the idea of legal theory as the core of NPLT’s methodological commitments, and second taking seriously its subject matter of private law as the source of its substantive underpinnings.Legal theory, I argue (much in line with GMR’s rich text), is distinctive from other discourses about law given its acute awareness to law’s normative filter, which furthermore implies a synthetic commitment that these other discourses do not share. But legal theory should also, I claim, be attentive to the constitutive role law plays in constructing the building-blocks of many of our interpersonal interactions, and it should thus be particularly cautious from relying on philosophical or social scientific inquiries that take contingent configurations of property or of contract as a given. This lesson, in turn, is crucial for contemporary discussions of private law obligations that go beyond the libertarian duty of non-interference. Rather than reifying the libertarian conceptions of property and contract and resorting to exogenous justifications for our interpersonal obligations of non-discrimination and accommodation, private law theory can—and indeed should—rely on happier conceptions of these core legal institutions, which vindicate the freestanding significance of these obligations and thus also validate their transnational applicability.
About the Methods of Studying Private Law: An Italian Perspective
Authors: Alpa Guido 
Published: July 2022

AbstractTaking as a starting point the book by Grundmann, Micklitz and Renner, New Private Law Theory, the author briefly examines the methods practised today in the most important legal systems for studying private law. There is no unanimous consensus on the definition of “private law”, nor on its functions. The formalistic method prevails, using terms, concepts, dogmas stratified over time, with an apparently technical content. In reality, as the three authors demonstrate, and as has been preached in Italy for more than half a century, law is a social science and its function can only be fully understood by combining the formalistic method with economic, sociological and political analysis and considering its historical development.
A Private Law Theory for Sustainable Legal Education?
Authors: Leone Candida 
Published: July 2022

AbstractNew Private Law Theory (“NPLT”) offers itself as almost a natural fit for legal education and in particular—I argue—legal education in the climate crisis. Yet, the world climate hardly features in the book and its impressive resource list. Without claiming to fill any existing gaps in the book, the Article seeks to articulate NPLT’s relevance to sustainable legal education and at the same time tease out what facing the, social, fact of the climate crisis would add to NPLT’s already rich framework.
Private Law Theory and the “Global Legal Community”
Authors: Michaels Ralf 
Published: July 2022

AbstractThe suggestion that the new private law theory would have to stand the test of acceptance by the global legal community raises a question. Who is that “global legal community?” And does it go beyond Europe? Close reading demonstrates that the non-European world is present and hidden at the same time. It is present because much of the material presented, many of the theories discussed, have transnational materials. However, the non-European world is hidden at the same time because it remains unaddressed, marginalized, and ignored. Including the Global South would make necessary a more radical pluralization of private law theory. This opens up the possibility of new, very different idea of a global legal community that is more improbable but also more attractive.