bluuebunny/crossref_metadata_2025_split huggingface dataset:
Complementary and alternate therapies (CAM) in the management of novel Corona virus (COVID-19): protocol for systematic review and meta-analysis
Authors: Maheshkumar Kuppusamy , Venugopal Vijayakumar. , Geethanjali Sankar , Poonguzhali Shanmugam , Silambanan Santhi , Padmavathi Ramaswamy , Venkateswaran Sankaralingam Thirupathy 
Published: June 2022

AbstractBackground:In December 2019, a new corona-virus (COVID-19) infection broke out in the Chinese province of Wuhan. With the rampant spread of virus around the world, COVID-19 was declared as a global pandemic in the following year. Many complementary and alternate therapies (CAM) were used experimentally alongside conventional treatments for effective management of COVID-19.Aim:This paper presents a protocol for the systematic review and meta-analysis of the studies with various CAM therapies for the management of COVID-19 pneumonia.Methods:Electronic databases such as PubMed, Embase, Scopus, and the Cochrane Central Register of Controlled Trials (CENTRAL) could be used for searching the relevant trials and studies with keywords related to COVID-19 and CAM therapies. Two independent reviewers would screen a list of all the trials and extract the relevant variables. Additionally, we would also evaluate the risk of bias of the selected studies. Review Manager software (RevMan; version 5.3.5) and R statistical software (version 3.6.1) would be used for the data analysis.Results:Risk ratio (RR) would be estimated for dichotomous outcomes, and the mean differences (MD) would be measured for continuous outcomes. Heterogeneity with the help of I2statistic would be used for the assessment of inconsistency across studies with the level of significance at P< 0.10. We would also assess publication bias using funnel plots and Egger’s test for the selected studies.Conclusion:The protocol for systematic review and meta-analysis would investigate the beneficial and possible adverse effects of various CAM therapies in the prevention and management of COVID-19 associated pneumonia.
BioChemUDM: a unified data model for compounds and assays
Authors: Kappler Michael A. , Lowden Christopher T. , Culberson J. Chris 
Published: June 2022

Abstract
We present a simple, biochemistry data model (BioChemUDM) to represent compounds and assays for the purpose of capturing, reporting, and sharing data, both biological and chemical. We describe an approach to register a compound based solely on a stereo-enhanced sketch, thereby replacing the need for additional user-specified “flags” at the time of compound registration. We describe a convention for string-based labels that enables inter-organizational compound and assay data sharing. By co-adopting the BioChemUDM, we have successfully enabled same-day exchange and utilization of chemical and biological information with various stakeholders.
Silent Poetry: The Disputation on the Immaculate Conception by Carlo Maratti, Revisited
Authors: Colombo Stefano 
Published: June 2022

Abstract
This paper re-examines the Disputation on the Immaculate Conception by Carlo Maratti (1686) and its reception in hitherto understudied poems which were first published in 1686 and 1687. Although the poems are chiefly celebratory and refer to the tradition of encomiastic pictorial description, this essay demonstrates how they help us understand the beholder’s engagement with Baroque art. It first analyzes the poems as both encomiastic speech and ekphrastic poetry to explain how epideictic description persuasively moves readers to venerate the Virgin, thus rekindling the cult of the Immaculate Conception. Subsequently, a comparative reading of the poems and the painting demonstrates how art and literature mutually informed each other to create new aesthetic and intellectual values. A detailed comparison between visual and verbal languages will therefore offer a new interpretative framework to reassess the painting, the poems, and their public.
EXTENSIVE EXPERTISE IN ENDOCRINOLOGY: My quarter century quest to understand the paradox of marrow adiposity
Authors: Rosen Clifford J 
Published: June 2022

Abstract
Understanding the development and regulation of marrow adiposity, as well as its impact on skeletal remodeling has been a major challenge for our field and during my career as well. The story behind this unique phenotype and its relationship to bone turnover is highlighted in my own quest to defining the physiology and pathophysiology of marrow adipocytes.
Elevated Parental Stress Is Associated With Lower Self-Efficacy in Provider Communication During a Pandemic
Authors: Jhingoeri Nataley , Tarini Beth A. , Barber John , Parikh Kavita 
Published: June 2022

BACKGROUND
Effective communication between physician and parent promotes a successful alliance with families. The association of parental stress with self-efficacy when communicating during parent-physician interactions is unknown in the context of a pandemic.

OBJECTIVES
Objectives of this study include quantifying and comparing the stress experienced by parents of hospitalized children before and after onset of the COVID-19 pandemic and examining the relationship of stress with self-efficacy in parent-physician communication during interactions throughout hospitalization.

METHODS
We conducted in-person surveys of parents of children aged 3 months to 17 years hospitalized at a quaternary-level children’s hospital, before and after onset of COVID-19. Parents completed 2 validated tools: Parenting Stress Index (PSI-SF) and the Perceived Efficacy in Parent-Physician Interactions (PEPPI), measuring self-efficacy in communicating with physicians. Socioeconomic data were collected. Fisher exact test and t test were used to compare score proportions and means; linear regression was used to evaluate association between PSI-SF and PEPPI with confounder adjustments.

RESULTS
Forty-nine parents were recruited; the majority identified as non-White and female. An inverse relationship was noted between the total stress score and parental self-efficacy, which only attained statistical significance in the post-COVID-19 cohort (P = .02, multivariate P = .044). A significant increase in the mean was observed for subscale scores of Difficult Child (P = .019) and Parent-Child Dysfunctional Interaction after COVID-19 (P = .016).

CONCLUSIONS
Elevated parental stress is associated with decreased self-efficacy during parent-physician interactions and it worsened during the pandemic. Future studies should examine the effect of different communication styles on parental stress and self-efficacy during hospitalization.
A Multisite Collaborative to Decrease Inappropriate Antibiotics in Urgent Care Centers
Authors: Nedved Amanda , Fung Melody , Bizune Destani , Liu Cindy M. , Obremskey Jill , Fleming-Dutra Katherine E. , Hamdy Rana F. , Montalbano Amanda 
Published: June 2022

BACKGROUND
Urgent care (UC; a convenient site to receive care for ambulatory-sensitive) centers conditions; however, UC clinicians showed the highest rate of inappropriate antibiotic prescriptions among outpatient settings according to national billing data. Antibiotic prescribing practices in pediatric-specific UC centers were not known but assumed to require improvement. The aim of this multisite quality improvement project was to reduce inappropriate antibiotic prescribing practices for 3 target diagnoses in pediatric UC centers by a relative 20% by December 1, 2019.

METHODS
The Society of Pediatric Urgent Care invited pediatric UC clinicians to participate in a multisite quality improvement study from June 2019 to December 2019. The diagnoses included acute otitis media (AOM), otitis media with effusion, and pharyngitis. Algorithms based on published guidelines were used to identify inappropriate antibiotic prescriptions according to indication, agent, and duration. Sites completed multiple intervention cycles from a menu of publicly available antibiotic stewardship materials. Participants submitted data electronically. The outcome measure was the percentage of inappropriate antibiotic prescriptions for the target diagnoses. Process measures were use of delayed antibiotics for AOM and inappropriate testing in pharyngitis.

RESULTS
From 20 UC centers, 157 providers submitted data from 3833 encounters during the intervention cycles. Overall inappropriate antibiotic prescription rates decreased by a relative 53.9%. Inappropriate antibiotic prescribing decreased from 57.0% to 36.6% for AOM, 54.6% to 48.4% for otitis media with effusion, and 66.9% to 11.7% for pharyngitis.

CONCLUSIONS
Participating pediatric UC providers decreased inappropriate antibiotic prescriptions from 60.3% to 27.8% using publicly available interventions.
Unresolved issues of increasing physical activity after myocardial infarction
Authors: Sedykh D. Yu. , Khryachkova O. N. , Krivoshapova K. E. , Tsygankova D. P. 
Published: June 2022

The review presents the results of studies on the problems of increasing the efficiency of rational physical activity within the concept of comprehensive secondary prevention of myocardial infarction. The aspects of insufficient adherence of specialists and patients to rehabilitation methods were discussed; possible safe exercise modes after infarction and available monitoring methods were given. We also described the potential characteristics of physical training, taking into account the initial clinical severity and completeness of revascularization after myocardial infarction. In addition, the need for socio-economic, as well as informational support of the state and healthcare system has been updated.
Echocardiographic phenomenon “RAC-sign” in the anomalous course of circumflex artery: a case report
Authors: Skaletsky K. V. , Namitokov A. M. , Donets E. K. , Kruchinova S. V. , Gagin V. A. , Kosmacheva E. D. 
Published: June 2022

Coronary artery (CA) anomalies are a group of congenital heart defects with a diverse clinical performance, from lifelong asymptomatic to severe consequences such as sudden cardiac death. In some cases, CA anomalies become an incidental finding during echocardiography. If there is a suspicion of CA anomaly, a radiographic investigation (computed tomography (CT) angiography or magnetic resonance imaging) should be performed to clarify the anatomy and indications for surgical correction.A case of diagnosing a tubular structure with hyperechoic walls in mitral valve projection during echocardiography is presented. The performed CT angiography confirmed the abnormal origin of circumflex artery from the right sinus of Valsalva with its retroaortic course. This echocardiographic sign is described in the English-language literature as Retroaortic Anomalous Coronary sign (RAC-sign).
Validation of the SIRENA score for assessing the risk of inhospital mortality in patients with acute pulmonary embolism in an independent sample
Authors: Cherepanova N. A. , Erlikh A. D. , Pavlova T. V. , Mullova I. S. , Duplyakov D. V. 
Published: June 2022

Aim. To validate the SIRENA score in assessing the risk of inhospital mortality in patients with pulmonary embolism (PE) in an independent sample.Material and methods. This retrospective, single-center study was based on the Samara Regional Cardiology Center. The risk of inhospital mortality was assessed using the SIRENA score, which includes such parameters as left ventricular ejection fraction <40%, immobilization in prior 12 months, creatinine clearance <50 ml/min, syncope, cyanosis on admission. For each positive sign, 1 point is assigned. Low risk is set at score of 0-1, high — ≥2.Results. The study included 452 patients with PE hospitalized from 2004 to 2019, of which 221 (48,9%) were men (mean age, 60,0 years (50,5-70,0)). With SIRENA score of 0, 1, 2, 3, and 4, inhospital mortality was 4,1%, 10,8%, 18,8%, 40,0%, and 100%, respectively. Mortality at SIRENA low risk (<2) was 7,1%, and at high risk (≥2) — 20,5% (odds ratio (OR), 3,34; 95% confidence interval (CI), 1,74-6,43; p<0,001). The predictive sensitivity and specificity for inhospital mortality for the SIRENA score were 70,5% and 60,8%, respectively. Area under the ROC-curve for the SIRENA score was 0,71 (95% CI, 0,63-0,79), while for Simplified Pulmonary Embolism Severity Index (sPESI) — 0,69 (95% CI, 0,60-0,77). With high risk on both scales (sPESI and SIRENA), inhospital mortality was 24,2% (OR, 4,09, 95% CI, 2,07-8,09; p<0,001).Conclusion. On an independent sample, the SIRENA score showed a high predictive ability in predicting adverse outcomes in patients with PE with a sensitivity of 70,5% and a specificity of 60,8% (AUC=0,71, 95% CI, 0,63-0,79), comparable with the sPESI.
Technical and Economic Analysis of a Conversion on a Single Pontoon to a Multi Pontoon Floating Dock
Authors:   Sepuluh Nopember Institute of Technology (ITS), Faculty of Marine Technology, Department of Marine Engineering, Indonesia, Wahidi Sufian Imam , Pribadi Triwilaswandio Wuruk , Firdausi Moch. Iqbal , Santosa Budie 
Published: June 2022

The conversion of floating docks from single pontoon to multi pontoon is a beneficial alternative for shipyards to enhance the performance of the facilities owned. The objective of this research is to analyze technically and economically the conversion of single pontoon floating dock to multi pontoon. The results of calculations used the 2.2	Finite Element Method software was the amount of the stress at the floating dock after the conversion of 14.635 MPa is smaller than the permitted stress of 160 MPa. Besides that, the pump ballast filling capability after conversion is 54.16 minutes. The decrease in Ton Lifting Capacity (TLC) can be determined by the difference in the load that occurs in the floating dock. After the floating dock is converted using the same TLC, it changes from 2.07 m to 2.11 m. The freeboard height is >300 mm so it is still able to work on the same TLC. There are 4 stages at the production stage, making access to the pontoon, installing bulkhead and additional reinforcement, removing the pontoon, dismantling and installing the pump, and reconnecting with the sidewall. The analysis results found that the conversion costs was IDR 20,051,463,949, the economic analysis conducted also obtained savings for floating dock reparation costs of IDR 6,559,475,128 to IDR 4,143,346,112. When one pontoon is repaired, the rest of the pontoon can still be used and get an income of IDR 3,292,265,120 thus the total cost is IDR 851,080,992. Saving amounting to IDR 5,708,394,136 is used to pay off investment costs.
Inversion of Infrasound Time Series for Seismoacoustic Source Parameters Produced by a Buried Chemical Explosion at the Source Physics Experiment Phase II: Dry Alluvium Geology
Authors: Berg Elizabeth M. , Poppeliers Christian 
Published: June 2022

ABSTRACT
We invert infrasonic timeseries produced by a single buried chemical explosion detonated as part of the Source Physics Experiment phase II Dry Alluvium Geology (DAG). The key to our inversion is that we use a three dimensional, fully coupled, linear, elastic-to-acoustic forward model to predict the recorded acoustic wavefield. We assume that the fourth buried chemical explosion in the series, DAG-4, produces an atmospheric acoustic wavefield due to a combination of direct elastic-to-acoustic coupling at the air–earth interface and ground upheaval, or spall, at the Earth’s surface. In our linear model we approximate these two phenomena with distinct source terms separated in space and time: (1) a buried point source consisting of six source time functions, each corresponding to a single component of a generalized moment tensor and (2) a vertically directed, time-variable force applied to the Earth’s surface. Inverting the infrasonic data with this linear forward model results in estimated source parameters that accurately predict the observed infrasound signals. To test our estimated buried source, we use the Rayleigh integral (RI) to model the infrasound signal from the measured and predicted acceleration surfaces. First, we simulate the infrasound signal waveforms using vertical accelerometer data and find that these closely match the observed infrasound. Next, using the estimated buried seismic source model without spall, we estimate the acceleration of the Earth’s surface using a linear approximation. When using the predicted surface acceleration in the RI, we simulate infrasound signals that reproduce pulse shape characteristics but not the amplitude of the observed infrasound, indicating our linear model does not completely account for nonlinear spall effects. Based on these results, we argue that for the scale of this experiment, purely linear models can estimate seismoacoustic source attributes and predict the far-field infrasonic signal, but the primary contribution to the infrasonic signal is the spall source.
Stock Market Manipulation: A Literature Review
Authors: Maxim Maruf Rahman 
Published: June 2022

This paper classifies the major types of stock market manipulation that have been observed over the past 30 years. The key objective of this paper is to summarize the findings of some of the leading research works done on stock market manipulation. This paper also talks about some of the major incidences of stock market manipulation that took place in various developed financial markets. Research on stock market manipulation is scarce, and this paper tries to give a holistic view of it to better understand it. Market manipulation is a dynamic problem. It’s been changing with time, with the advancement of technology, and with the evolution of financial markets. This paper exhibits this characteristic of stock market manipulation and explains how it has been changing over time.
JEL Classification Code: G14
PARTICIPAÇÃO ELEITORAL NA VENEZUELA CONTEMPORÂNEA: UMA [BREVE] PROBLEMATIZAÇÃO À TEORIA INSTITUCIONALISTA DA ESCOLHA RACIONAL
Authors: De Moraes Cicero Pedro Henrique 
Published: June 2022

Resumo
Através de um estudo de caso – o processo
político em curso na Venezuela - o
artigo tem como objetivo problematizar as
bases conceituais da teoria institucionalista
da escolha racional, em especial o que concerne
às suas assertivas sobre o fenômeno
da participação eleitoral. A partir desse
exercício teórico, o texto procura compreender
os motivos da considerável variação
na abstenção eleitoral para, em seguida,
argumentar que não é prudente dissociar
o “componente político” das análises
sobre a participação eleitoral na Venezuela
contemporânea.
Palavras-chave
Abstenção Eleitoral ;Teoria da Escolha
Racional; Venezuela.
MIGRANTES NORDESTINOS NO VALE DO RIO BRANCO
Authors: Da Silva Neto Manoel Aires 
Published: June 2022

Resumo
O presente artigo discute a migração de
nordestinos para o vale do Rio Branco
entre 1890 e 1930. Dessa forma, dentro
da dinâmica do movimento migratório
desencadeado entre o Nordeste e a Amazônia
nos tempos áureos da borracha, vale
ressaltar que o Rio Branco permaneceu
à margem desse processo. Exceto pela presença
de algumas famílias cearenses, paraibanas,
piauienses, ligadas principalmente
à criação de gado, além de trabalhadores
desmobilizados após a crise da borracha.
Busca também analisar alguns aspectos do
cotidiano da vila de Boa Vista, utilizando
como fonte os diários dos viajantes
que percorreram a região nesse período,
permitindo vislumbrar a formação de uma
sociedade na qual os migrantes buscaram
reproduzir as características do lugar de
origem.
Palavras-chave
Corrente migratória; Nordestinos; Amazônia;
Vale do Rio Branco.
RELAÇÕES BILATERAIS ENTRE BRASIL E VENEZUELA ATRAVÉS DOS ESTADOS DE RORAIMA E BOLÍVAR
Authors: Viana Ana Carolina , De Queiroz Olendina Bonet 
Published: June 2022

Este artigo baseia-se em um estudo exploratório sobre a região de fronteira entre o Brasil e a Venezuela, que teve como objetivo investigar as relações entre os Estados vizinhos Roraima (Brasil) e Bolívar (Venezuela). A pesquisa investigou a existência de Tratados, Acordos, Memorandos e Termos de Compromisso entre os dois Estados, nas diversas áreas importantes para o desenvolvimento sócio-econômico. Buscou-se conhecer os frutos dessas parcerias, bem como os entraves e o potencial dessas relações. Os resultados mostram que a posição geográfi ca de Roraima é bastante estratégica, tendo em vista o contexto das relações internacionais (fl uxos de mercadorias, migrantes, turistas, investimentos e serviços, relações econômicas e políticas entre esses países) e o comércio exterior brasileiros, o que torna a geopolítica de Roraima algo extremamente relevante. Grande parte das relações entre Brasil e Venezuela que acontecem na área de fronteira é mediada pelos estados vizinhos Roraima (Brasil) e Bolívar (Venezuela), que desde o ano de 2006 tem estreitado suas relações produzindo uma integração com resultados concretos e satisfatórios nas áreas de educação, segurança pública, saúde e, a passos mais lentos, a agricultura
Palavras-Chave
Fronteira, Geopolítica, Território, Integração
A COMPLEXIDADE DA PROVISÃO DE SERVIÇOS SOCIAIS
Authors: França Sette Pinheiro J Fernando Antônio 
Published: June 2022

O trabalho busca apresentar os motivos pelos quais o Estado é visto como provedor de políticas sociais a partir das ideias de direitos civis, políticos e sociais, e que esses apresentam uma ordem lógica e cronológica. Para isso expõe que o regime adotado em um país quanto à provisão de serviços e criação de políticas sociais possui forte relação com os papéis atribuídos à tríade Estado, mercado e família, que formam os pilares de sustentação para a garantia dos serviços sociais e do bem-estar dos indivíduos. A partir disso, se demonstra que o Estado e o mercado interagem continuamente ao longo da história e defi nem as formas de provisão social presentes nos países, variando de acordo com as demandas da sociedade, que sofrem alterações na medida em que há mudanças nas estruturas familiares. A partir do momento em que se analisam as necessidades humanas, e se defi ne, seja legalmente ou por meio de um mandato governamental, quais são dadas como direitos sociais (iniciativa pública) e quais são relegadas ao mercado (iniciativa privada) é possível analisar as escolhas. Para aquelas tidas como direito social o Estado passa a colocar sobre sua responsabilidade a execução de determinados serviços sociais, e esses passam a ser considerados políticas públicas com cunho social, ou seja, são políticas sociais. Assim, o trabalho busca apresentar o motivo pelo qual o Estado é provedor de serviços sociais, e de como esses serviços sociais são escolhidos para a provisão.
Palavras-chave
Políticas Sociais, Estado, Família, Mercado.