bluuebunny/crossref_metadata_2025_split huggingface dataset:
Léxico culinario en los «Elementos de higiene privada» (1846) de Pedro Felipe Monlau
Authors: Torres Martínez Marta 
Published: February 2022

The present research deals with Elementos de higiene privada (1846), a treatise by Pedro Felipe Monlau about hygiene from the late 19th century. Our main objective is to study the culinary lexicon within this work, particularly the third section, dedicated to food science, where several intriguing chapters can be found, as the one titled “Preparation and Preservation of Food” (pp. 150-164). In accordance with Eberenz (2014: 30), apart from focusing on the culinary treatise, a historical lexicographer has to pay attention to a more varied textual typology. Particularly, we aim to organize the documented specialty terms in order to revise their presence, treatment and evolution in the Spanish lexicographic tradition.
En esta investigación nos aproximamos a un tratado sobre higiene publicado a finales del siglo XIX, Elementos de higiene privada (1846) de Pedro Felipe Monlau. Nuestro objetivo consiste en estudiar el léxico culinario incluido en esta obra, concretamente en la sección tercera, dedicada a la Bromatología, donde se encuentran capítulos tan sugerentes como el titulado “Preparación y conservación de los alimentos” (pp. 150-164). Siguiendo a Eberenz (2014: 30) consideramos que, además de centrar el interés en los tratados culinarios, un historiador del léxico ha de prestar atención a una tipología textual más variada. En particular, nos disponemos a organizar las voces de especialidad documentadas para después revisar su presencia, tratamiento y evolución en la tradición lexicográfica del español.
Venusins Autografer
Authors: Andersen Peter 
Published: February 2022

Peter Andersen: Venusinus’s autographs
Today thirteen autograph manuscripts are known by the Danish humanist Jon JacobsenVenusinus (d. 1608), cited in older research particularly with reference to his oppositionto exorcism. His enemies compared him to Faust; an admirer described him as ‘theman with the enchanting name’. He first called himself Coronensis, alluding both tohis upbringing in Landskrona and to his close association with the royal house, but hechanged his name about 1595 to Venusinus, referring both to Ven, the island on whichhe claimed to have been born, and Venusia, Horace’s home town. Seven bookplatesprovide an insight into this Dane’s personal library. Among his books was a copy ofWilliam Lambarde’s Archaionomia, from which he quotes twenty-four Old English words.Five entries in his alba amicorum bear witness to his circle of friends, which includedseveral Calvinists. Three entries contain his hitherto neglected Latin and Greek mottos.The albums also allow partial reconstruction of his travels abroad. A recently rediscoveredletter to the German Calvinist Johannes Piscator is particularly interesting anddoubles the quantity of known text from Venusinus’s hand.
Land use and land cover dynamics and traditional agroforestry practices in Wonchi District, Ethiopia
Authors: Meragiaw Misganaw , Woldu Zerihun , Singh Bal Ram 
Published: February 2022

Background
Investigating the land use and land cover (LULC) dynamics and the status of traditional agroforestry practices provide important data for policymakers. The main objective of this study was to assess the LULC dynamics and traditional agroforestry practices among smallholder farmers across the two agro-ecological zones in Wonchi District of Ethiopia.

Methods
Landsat images were acquired from Earth Explorer, and changes in LULC were quantified with three Landsat sensors in the three time-series (1985, 2001, and 2019). Supervised classification with maximum likelihood technique was employed using ERDAS Imagine and ArcGIS. A ground survey was conducted with 100 key informants who were selected from 10 sites using a purposive sampling method. The collected data were subjected to direct matrix ranking, use-value analysis of most important multipurpose plant species, and semi-structured interviews were conducted for qualitative analysis.

Results
In total, 103 agroforestry plant species belonging to 44 families were identified in Wonchi District, of which 74 were indigenous including seven endemic and 29 exotic species. The highest species (13) were recorded in the Fabaceae family. About 61% of species were reported in the midland agro-ecological zone. A mixed farming system was the most frequently (56%) reported source of income. The results of LULC changes from 1985 to 2019 showed that the agroforestry cover increased from 31.1% to 34.9% and settlement including road construction increased from 12.5% to 31.6% of the total area with an annual rate change of 0.3% and 2.7%, respectively. These changes corresponded with a decreasing trend of the forest, cropland, water body, and shrub at a rate of 4.7%, 1.3%, 0.8%, and 0.5%, respectively. The LULC changes were more pronounced in the highlands than in the midlands of Wonchi District. Expansion of settlement and tenure policy change are the main drivers for these changes in the area. The authors recommended that protecting and planting indigenous and multipurpose plant species is essential as restoration techniques for all degraded land-use types. Therefore, strengthening agroforestry practices and land-use planning is urgently needed for achieving multiple goals.
Acesso à Justiça e Audiência Virtual no Contexto da Pandemia de Covid-19
Authors: Morais Káty Maria Nogueira , Rodrigues Diana Cruz , Vasconcellos Ana Maria de Albuquerque , Soares Junior Eden do Carmo 
Published: February 2022

A temática do acesso à Justiça tem como uma de suas premissas a aproximação entre o Sistema de Justiça e a sociedade. No contexto da transformação digital, que foi intensificada em razão da crise sanitária da Covid-19, a discussão de como ocorre o acesso à Justiça em formatos digitais torna-se relevante, em especial em cenário periférico, incluindo cidades que pertencem à Amazônia Legal maranhense. O objetivo desta pesquisa é examinar as potencialidades e limitações ao acesso à Justiça de cidadãos por meio das audiências virtuais realizadas durante a pandemia da Covid-19 pelo Tribunal de Justiça do Estado do Maranhão (TJMA). Metodologicamente, a investigação é baseada em um estudo de caso qualitativo e exploratório, que tem como lócus o TJMA, através da observação não-participante das audiências virtuais e de análise documental. Os resultados coletados indicam que as sessões virtuais contribuíram para a continuidade da atividade jurisdicional, contudo foram observadas a necessidade de adaptações, conforme as condições de acesso de magistrados, advogados e partes. Dentre as potencialidades podem ser destacadas as reduções de custos e do excesso de formalismo em comparação com a audiência presencial e como limitações, indicam-se as desigualdades de estrutura de acesso à internet ou equipamentos, bem como a necessidade de adaptação que pode influenciar na interação dos participantes. O estudo suscita temas para aprofundamento quanto às questões de exposição, publicização e assimetrias de condições técnicas e acompanhamento dos defensores no acesso às sessões por cidadãos.
Overexpression of Peroxiredoxin 3 in Cartilage Reduces the Severity of Age‐Related Osteoarthritis But Not Surgically Induced Osteoarthritis in Mice
Authors: Loeser Richard F. , Coryell Philip R. , Armstrong Alexandra R. , Collins John A. , Gopalakrishnan Priya , McDermott Katie A. , Ran Qitao , Carlson Cathy S. 
Published: February 2022

ObjectiveThe study objective was to determine whether overexpression of the mitochondrial antioxidant peroxidase, peroxiredoxin 3 (Prx3), reduces the severity of osteoarthritis (OA) in mice.MethodsAge‐related OA (age 18 and 24 months) and OA induced by destabilization of the medial meniscus (DMM at age 6 months) were assessed in male mice that overexpress a human Prdx3 transgene encoding the Prx3 protein. Lox‐stop‐lox‐Prdx3 (iPrdx3) mice were crossed with aggrecan‐CreERT2 mice to produce iPrdx3AgCreERT2 or with Col2Cre to produce iPrdx3Col2Cre mice. Germline transgenics (Prdx3Tg) were also evaluated. Prx3 protein level was assessed by immunoblotting and functionally after induction of elevated mitochondrial hydrogen peroxide (H2O2) using menadione. Histological sections of stifle joints were scored for cartilage damage (Articular Cartilage Structure score [ACS]), osteophytes, and synovial hyperplasia and were evaluated by histomorphometry.ResultsOverexpression of Prx3 maintained mitochondrial membrane integrity and inhibited p38 phosphorylation in the presence of elevated H2O2. ACS scores of 18‐month‐old iPrdx3AgCreERT2 mice (mean ± SD, 4.88 ± 5.05) were significantly lower than age‐matched iPrdx3 controls (11.75 ± 6.34, P = 0.002) and trended lower in the 18‐month Prdx3Tg group (P = 0.14), whereas no significant differences between experimental and control groups at 24 months of age or in OA induced by DMM surgery were noted. Osteophyte scores trended lower in the 18‐month‐old Prdx3Tg group (P = 0.09) and at 24 months in the iPrdx3Col2Cre mice (P = 0.05). There were no significant group differences in synovial hyperplasia or histomorphometric measures.ConclusionOverexpression of the mitochondrial peroxidase Prx3 reduced the severity of age‐related OA, but not at advanced ages and not in DMM‐induced OA in younger mice.
A High‐Fidelity Skin‐Attachable Acoustic Sensor for Realizing Auditory Electronic Skin
Authors: Lee Siyoung , Kim Junsoo , Roh Hajung , Kim Woongji , Chung Sein , Moon Wonkyu , Cho Kilwon 
Published: February 2022

AbstractWearable auditory sensors are critical in user‐friendly sound‐recognition systems for smart human–machine interaction and the Internet of Things. However, previously reported wearable sensors have limited sound‐sensing quality as a consequence of a poor frequency response and a narrow acoustic‐pressure range. Here, a skin‐attachable acoustic sensor is presented that has higher sensing accuracy in wider auditory field than human ears, with flat frequency response (15–10 000 Hz) and a good range of linearity (29–134 dBSPL) as well as high conformality to flexible surfaces and human skin. This high sound‐sensing quality is achieved by exploiting the low residual stress and high processability of polymer materials in a diaphragm structure designed using acousto‐mechano‐electric modeling. Thus, this acoustic sensor shows high acoustic fidelity by sensing human‐audible sounds, even loud sounds and low‐frequency sounds that human ears cannot detect without distorting them. The polymer‐based ultrasmall (<9 mm2) and thin sensor maintains sound‐detection quality on flexible substrates and in a wide temperature range (25 to 90 °C). The acoustic sensor shows a significant potential of auditory electronic skin, by recognizing voice successfully when the sensor attached on human skin is connected to a commercial mobile device running the latest artificial intelligence assistant.
Band‐Like Charge Transport in Small‐Molecule Thin Film toward High‐Performance Organic Phototransistors at Low Temperature
Authors: Ji Deyang , Jiang Ting , Zheng Yingshuang , Sun Yajing , Wei Zhongming , Li Liqiang , Hu Wenping 
Published: February 2022

AbstractOrganic phototransistors (OPTs) are playing an indispensable role in organic optoelectronics, which greatly show their promising application in optical communication, video imaging, missile guidance, and night vision. However, because the thermally activated mode dominated for thin‐film devices leads to a sharp drop in mobility at low temperatures, until now, most of the studies about OPTs are performed at room temperature, severely hindering their further potential optoelectronic application over a broad range of temperatures, especially at low temperature environment. In this work, the optoelectronic properties of a small molecule (2,6‐diphenylanthracene, DPA) based OPTs with band‐like transport are studied at low temperatures. The devices exhibit outstanding optoelectronic properties in terms of mobility (2.6 cm2 V−1 s−1), on/off ratio (≈104), detectivity (1013 Jones), and external quantum efficiency (2500%) even at 150 K, which is superior to the performance of devices with thermally activated mode. In addition, the organic photodetector at low temperatures is also fabricated. Our results demonstrate that organic π‐conjugated DPA small‐molecule has great potential in low‐temperature application.
3D Spatial Combination of CN Vacancy‐Mediated NiFe‐PBA with N‐Doped Carbon Nanofibers Network Toward Free‐Standing Bifunctional Electrode for Zn–Air Batteries
Authors: Lai Chenglong , Li Haomiao , Sheng Yi , Zhou Min , Wang Wei , Gong Mingxing , Wang Kangli , Jiang Kai 
Published: February 2022

AbstractConstructing flexible free‐standing electrodes with efficient bifunctional performance is significant for improving the performance of flexible Zinc–air batteries. Herein, a flexible free‐standing bifunctional electrode (N2‐NiFe‐PBA/NCF/CC‐60) is constructed by the 3D spatial combination of CN vacancy‐mediated NiFe Prussian Blue Analogue (NiFe‐PBA) and N‐doped carbon nanofibers (NCF) rooted on carbon cloth (CC). The in situ formed CN vacancies by N2‐plasma activation tune the local coordination environment and electronic structure of Ni‐Fe active sites in NiFe‐PBA, thus improving the oxygen evolution reaction (OER) catalytic intrinsic activity, and restraining the loss of Fe element during OER process. The combination of NiFe‐PBA and NCF presents a 3D interworking network structure, which exhibits a large specific surface and excellent electrical conductivity, thus guaranteeing sufficient, stable, and efficient oxygen reduction reaction (ORR)/OER active sites. Therefore, the N2‐NiFe‐PBA/NCF/CC‐60 electrode delivers high‐efficiency OER activity with a low overpotential (270 mV at 50 mA cm−2) and excellent ORR performance with a positive potential of 0.89 V at 5 mA cm−2. The N2‐NiFe‐PBA/NCF/CC‐60 based Zn–air batteries display outstanding discharge/charge stability for 2000 cycles. Meanwhile, the corresponding flexible Zn–air batteries with satisfactory mechanical properties exhibit a low voltage gap of 0.52 V at 1.0 mA cm−2.
Mechanochemical Access to a Short‐Lived Cyclic Dimer Pd2L2: An Elusive Kinetic Species En Route to Molecular Triangle Pd3L3and Molecular Square Pd4L4
Authors: Liu Yan , Liu Fang‐Zi , Yan KaKing 
Published: February 2022

AbstractPd‐based molecular squarePd4L4and trianglePd3L3represent the molecular ancestors of metal‐coordination polyhedra that have been an integral part of the field for the last 30 years. Conventional solution‐based reactions betweencis‐protected Pd ions and 2,2′‐bipyridine exclusively givePd4L4and/orPd3L3as the sole products. We herein show that, under solvent‐free mechanochemical conditions, the self‐assembly energy landscape can be thermodynamically manipulated to form an elusive cyclic dimerPd2L2for the first time. In the absence of solvent,Pd2L2is indefinitely stable in the solid‐state, but converts rapidly to its thermodynamic productsPd3L3andPd4L4in solution, confirmingPd2L2as a short‐lived kinetic species in the solution‐based self‐assembly process. Our results highlight how mechanochemistry grants access to a vastly different chemical space than available under conventional solution conditions. This provides a unique opportunity to isolate elusive species in self‐assembly processes that are too reactive to both “see” and “capture”.
Anaesthesia management of a child with aromatic L‐amino acid decarboxylase deficiency
Authors: McCarthy A. , Black C. 
Published: February 2022

SummaryAromatic L‐amino acid decarboxylase deficiency is an autosomal recessive disorder that results in a lack of neurotransmitters including serotonin, dopamine, noradrenaline and adrenaline. It is characterised by developmental delay, severe hypotonia and autonomic disturbance. In patients with this condition, catecholamine deficiency and autonomic dysfunction, resulting in haemodynamic instability under anaesthesia is a primary concern. There is increased sensitivity to exogenous catecholamines and indirect acting agents, such as ephedrine, are ineffective. Hypoglycaemia, difficult airway status and drug interactions such as with monoamine oxidase inhibitors are also of concern, and these patients are at risk of dystonic crises peri‐operatively. A 6‐year‐old boy with aromatic L‐amino acid decarboxylase deficiency presented for gastrointestinal endoscopy. Following multidisciplinary discussion, we elected to provide general anaesthesia with a propofol target‐controlled infusion, which proceeded without incident. In this report, we describe the precautions taken in this case, and discuss the provision of general anaesthesia for children with rare neurometabolic disorders.
Are social sciences becoming more interdisciplinary? Evidence from publications 1960–2014
Authors: Zhou Hongyu , Guns Raf , Engels Tim C. E. 
Published: February 2022

AbstractInterdisciplinary research is widely recognized as necessary to tackle some of the grand challenges facing humanity. It is generally believed that interdisciplinarity is becoming increasingly prevalent among Science, Technology, Engineering, and Mathematics (STEM) fields. However, little is known about the evolution of interdisciplinarity in the Social Sciences. Also, how interdisciplinarity and its various aspects evolve over time has seldom been closely quantified and delineated. This paper answers these questions by capturing the disciplinary diversity of the knowledge base of scientific publications in nine broad Social Sciences fields over 55 years. The analysis considers diversity as a whole and its three distinct aspects, namely variety, balance, and disparity. Ordinary least squares (OLS) regressions are also conducted to investigate whether such change, if any, can be found among research with similar characteristics. We find that learning widely and digging deeply have become one of the norms among researchers in Social Sciences. Fields acting as knowledge exporters or independent domains maintain a relatively stable homogeneity in their knowledge base while the knowledge base of importer disciplines evolves towards greater heterogeneity. However, the increase of interdisciplinarity is substantially smaller when controlling for several author and publication related variables.
The study of expression levels of DNA methylation regulators in patients affected with congenital heart defects (CHDs)
Authors: Joshi Radha O. , Kukshal Prachi , Chellappan Subramanian , Guhathakurta Soma 
Published: February 2022

AbstractBackgroundCongenial heart defects (CHDs) have multifactorial etiology with complex interplay of genetic and environmental factors. Environmental impact can have epigenetic mechanism of CHD development. Many studies have reported the causal association between CHD and distinct DNA methylation profile which is one of the key epigenetic events, which has vital role in normal embryonic development. The products of DNMT1, DNMT3A, DNMT3B, and MBD2 are important regulators of DNA methylation process. Changes in the expression of these genes are implicated in congenital structural cardiac defects. Hence, in this proof‐of‐concept study, we have compared the expression levels of these genes in the blood samples of healthy controls and CHD cases while investigating the etiology of CHD.MethodsIn this study with 48 CHD cases and 47 healthy controls, total RNA was isolated from the whole blood samples using TRI reagent. Quantitative RT PCR (qRT‐PCR) was used to analyze the mRNA levels of DNMT1, DNMT3A, DNMT3B, and MBD2. The expression levels have been analyzed by relative quantification.ResultsWe observed that DNMT3B (fold change = −2.563; p = .0018) and DNMT3A (fold change = −2.169; p = .05) were significantly downregulated in CHD patients, whereas the expression of DNMT1 and MBD2 was not significantly different between cases and controls.ConclusionsLower expression of de novo methyltransferases, namely, DNMT3B and DNMT3A in CHD cases, may be an important contributor to the mechanism of CHD pathogenesis. Further studies with age‐matched controls and analysis of global DNA methylation profile are required to investigate the proposed causal association.
Computational investigation of dynamical heterogeneity in ionic liquids based on the restricted primitive model
Authors: Lim Hyuntae , Jung YounJoon 
Published: February 2022

AbstractThe locally heterogeneous dynamics of the glass‐forming liquids is an unusual and distinct phenomenon that is not observed in a typical liquid system above the melting temperature. Room‐temperature ionic liquids (RTILs) are usually good glass formers, exhibiting various interesting features of glassy materials such as nonexponential and non‐Arrenhius relaxations and transport decoupling behaviors. In this study, we propose a minimal model that represents the general structural features of RTILs to study their dynamics by extending the restricted primitive model. We mainly focus on the heterogeneous dynamics of the RTIL as a glass former and investigate how the charge symmetry of each ion affects the structural relaxation, diffusive behavior, and the dynamic heterogeneity lifetime of the system.
Experimental early‐life febrile seizures cause a sustained increase in excitatory neurotransmission in newborn dentate granule cells
Authors: Hoogland Govert , Raijmakers Marjolein , Clynen Elke , Brône Bert , Rigo Jean‐Michel , Swijsen Ann 
Published: February 2022

AbstractProlonged febrile seizures (FS) are a risk factor for the development of hippocampal‐associated temporal lobe epilepsy. The dentate gyrus is the major gateway to the hippocampal network and one of the sites in the brain where neurogenesis continues postnatally. Previously, we found that experimental FS increase the survival rate and structural integration of newborn dentate granule cells (DGCs). In addition, mature post‐FS born DGCs express an altered receptor panel. Here, we aimed to study if these molecular and structural changes are accompanied by an altered cellular functioning. Experimental FS were induced by hyperthermia in 10‐days‐old Sprague‐Dawley rats. Proliferating progenitor cells were labeled the next day by injecting green fluorescent protein expressing retroviral particles bilaterally in the dentate gyri. Eight weeks later, spontaneous excitatory and inhibitory postsynaptic events (sEPSCs and sIPSCs, respectively) were recorded from labeled DGCs using the whole‐cell patch‐clamp technique. Experimental FS resulted in a robust decrease of the inter event interval (p < .0001) and a small decrease of the amplitude of sEPSCs (p < .001). Collectively the spontaneous excitatory charge transfer increased (p < .01). Experimental FS also slightly increased the frequency of sIPSCs (p < .05), while the amplitude of these events decreased strongly (p < .0001). The net inhibitory charge transfer remained unchanged. Experimental, early‐life FS have a long‐term effect on post‐FS born DGCs, as they display an increased spontaneous excitatory input when matured. It remains to be established if this presents a mechanism for FS‐induced epileptogenesis.