bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perturbative calculation of supersymmetric gradient flow in 𝒩 = 1 supersymmetric QCD
Authors: Kadoh Daisuke , Maru Nobuhito , Suzuki Mitsuyo , Ukita Naoya 
Published: December 2022

Abstract
We demonstrate perturbative calculations of supersymmetric gradient flow in four-dimensional ${\mathcal {N}=1}$ supersymmetric quantum chromodynamics (SQCD). A remarkable property of the gradient flow is to make ultraviolet (UV) divergences of flowed field correlators milder. To illustrate this property, we calculate two-point functions for the flowed fields in SQCD at the one-loop level and investigate their UV divergence structure. After renormalizing the SQCD at the boundary, the two-point functions of flowed gauge supermultiplets are shown to be UV-finite. On the other hand, those for flowed matter supermultiplets require extra wave function renormalization, which are found to be the common factor for all the fields in the multiplets.
In situ self-assembly of amphiphilic dextran micelles and superparamagnetic iron oxide nanoparticle-loading as magnetic resonance imaging contrast agents
Authors: Jiang Linrui , Zheng Rong , Zeng Ni , Wu Changqiang , Su Hongying 
Published: December 2022

Abstract
Polymeric micelles have long been considered as promising nanocarrier for hydrophobic drugs and imaging probes, due to their nanoscale particle size, biocompatibility and ability to loading reasonable amount of cargoes. Herein, a facile method for dextran micelles preparation was developed and their performance as carriers of superparamagnetic iron oxide (SPIO) nanocrystals was evaluated. Amphiphilic dextran (Dex-g-OA) was synthesized via the Schiff base reactions between oxidized dextran and oleylamine, and self-assembled in situ into nano-size micelles in the reaction systems. The self-assembling behaviors of the amphiphilic dextran were identified using fluorescence resonance energy transfer technique by detection the energy transfer signal between the fluorophore pairs, Cy5 and Cy5.5. Hydrophobic SPIO nanoparticles (Fe3O4 NPs) were successfully loaded into the dextran micelles via the in situ self-assembly process, leading to a series of Fe3O4 NPs-loaded micelle nanocomposites (Fe3O4@Dex-g-OA) with good biocompatibility, superparamagnetism and strongly enhanced T2 relaxivity. At the magnetic field of 0.5 T, the Fe3O4@Dex-g-OA nanocomposite with particle size of 116.2 ± 53.7 nm presented a higher T2 relaxivity of 327.9 mMFe−1·s−1. The prepared magnetic nanocomposites hold the promise to be used as contrast agents in magnetic resonance imaging.
Recent advances in regenerative biomaterials
Authors: Cao Dinglingge , Ding Jiandong 
Published: December 2022

AbstractNowadays, biomaterials have evolved from the inert supports or functional substitutes to the bioactive materials able to trigger or promote the regenerative potential of tissues. The interdisciplinary progress has broadened the definition of ‘biomaterials’, and a typical new insight is the concept of tissue induction biomaterials. The term ‘regenerative biomaterials’ and thus the contents of this article are relevant to yet beyond tissue induction biomaterials. This review summarizes the recent progress of medical materials including metals, ceramics, hydrogels, other polymers and bio-derived materials. As the application aspects are concerned, this article introduces regenerative biomaterials for bone and cartilage regeneration, cardiovascular repair, 3D bioprinting, wound healing and medical cosmetology. Cell-biomaterial interactions are highlighted. Since the global pandemic of coronavirus disease 2019, the review particularly mentions biomaterials for public health emergency. In the last section, perspectives are suggested: (i) creation of new materials is the source of innovation; (ii) modification of existing materials is an effective strategy for performance improvement; (iii) biomaterial degradation and tissue regeneration are required to be harmonious with each other; (iv) host responses can significantly influence the clinical outcomes; (v) the long-term outcomes should be paid more attention to; (vi) the noninvasive approaches for monitoring in vivo dynamic evolution are required to be developed; (vii) public health emergencies call for more research and development of biomaterials; and (viii) clinical translation needs to be pushed forward in a full-chain way. In the future, more new insights are expected to be shed into the brilliant field—regenerative biomaterials.
Effects of Substrate and Processing Conditions on Nematode Suppressiveness of Anaerobic Biogas Digestates
Authors: Eberlein Caroline , Edalati Abdelhossein , Zhang Ruihong , Westphal Andreas 
Published: December 2022

Biogas digestates produced from anaerobically processed food or dairy manure have demonstrated some potential to suppress different pathogens and pests. In this study, digestates from these two substrates processed mesophilically (20 to 40°C) or thermophilically (>40°C) were compared for their nematode-suppressive potential. In bioassays, the suppressive potential of Heterodera schachtii or Meloidogyne incognita was tested at different amendment rates. Testing was expanded to field microplot experiments with M. incognita and greenhouse tests with Pratylenchus vulnus. In the bioassay with H. schachtii, fewer nematodes penetrated radish roots after amendment with thermophilic than with mesophilic digestates. Root penetration was lowest after treatment with digestates of food waste and thermophilic dairy manure at the highest rate. In a watermelon bioassay with M. incognita, nematode-induced galling and egg mass production were reduced after amendment with food waste digestates compared with manure digestates and after thermophilic compared with mesophilic digestates in the case of egg masses. In a greenhouse experiment with peach rootstock ‘Nemaguard’, the numbers of P. vulnus in roots were diminished after amendment with digestates at the highest rate. In microplot experiments with bell peppers, plants initially were more vigorous after amendment with thermophilic digestates than after mesophilic digestate additions. This effect was transient and was no longer measurable at harvest. In summary, food waste digestates, especially those that were thermophilically produced, had nematode suppressive and plant growth-improving properties. These effects were not long lasting and probably need additional mitigation for practical utility. [Formula: see text] Copyright © 2023 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license .
The Chances of Obtaining a Euploid Embryo and Subsequent Live Birth Remain Consistent With National Age-Based Rates After an In Vitro Fertilization Cycle That Produced Only Aneuploid Embryos
Authors: Herlihy Nola S. , Klimczak Amber M. , Cheung Jessica K. W. , Seli Emre , Scott Richard T. 
Published: December 2022

(Abstracted from Fertil Steril 2022;118:484–491)
Despite significant advances over the last several decades in assisted reproductive technology, many embryos still fail to get implanted. Preimplantation embryo diagnostics has received considerable attention to identify markers of true “reproductive competence.” One consequence of having more information on embryo quality in a single cohort is when all embryos are diagnosed as being abnormal, including aneuploid.
General Anesthesia and the Premature Baby: Identifying Risks for Poor Neurodevelopmental Outcomes
Authors: Price Jerri C. , Lei Susan , Diacovo Thomas G. 
Published: December 2022

Preterm birth affects 1 in every 10 infants born in the United States. Importantly, more preterm infants are surviving to discharge from hospital, including those born at the cusp of viability (eg, 22 to 24 wk gestation). Such improvements, however, come at a cost as those delivered at less than 28 weeks gestation have the highest rates of morbidity and mortality. To complicate matters, these extremely preterm infants often require multiple surgical procedures resulting in repeated and prolonged exposures to anesthetic, analgesic, and sedative agents both during procedures and in the neonatal intensive care unit. Consequently, all of these factors, including premature birth itself, correlate with a higher risk for neurodevelopmental disabilities. More studies are needed to address the effects of prematurity-related morbidities and drug exposures on this vulnerable population, with the goal of improving neurodevelopmental outcomes. This brief review will discuss risk factors that impact neurodevelopmental outcomes in premature infants, with a particular focus on anesthetic, analgesic, and sedative agents.
Memory Problems in Children With Congenital Heart Disease: A Narrative Review
Authors: Jackson William M. , Monteleone Matthew , Kim An , Ko Riva 
Published: December 2022

Introduction:
Care for congenital heart diseases (CHD) has improved significantly over the past several decades, and children with CHD are now surviving into adulthood. Cognitive and behavioral problems affect children with CHD more than healthy peers. A review of performance on neuropsychological memory tasks has not been reported. We aimed to summarize the published literature on memory problems in people with CHD.

Methods:
We searched Pubmed, Medline, and PsycINFO from January 1, 1986 to March 22, 2022 to reflect modern care for people with CHD. Our inclusion criteria were randomized controlled trials or observational studies that included children with CHD older than age 3 years, which reported the results of at least 1 neuropsychological test of memory in the CHD group. Our exclusion criteria were studies that included heart transplant recipients and studies that included children who required extracorporeal membrane oxygenation.

Results:
Thirty-one studies that met our inclusion criteria and avoided exclusion criteria were included in this review. Several studies reported deficits in the subdomains of short-term and long-term memory and visual and verbal memory, though we found substantial heterogeneity across studies. The most likely subdomain to be affected in children with CHD appears to be short-term visual memory.

Conclusions:
There is likely an increased risk of memory problems for children and adults with CHD. We were unable to quantify the risk of memory problems due to the heterogeneity of published studies. Future research should make efforts to account for confounding variables and standardize outcome measures.
Combining Medial Patellofemoral Ligament Reconstruction With Patellar Tendon Repair Using Biocomposite Swivel Lock Anchors: Surgical Technique and Case Report
Authors: Falbo Ryan A. , Simmons Elizabeth , Singleton Amy , Stegelmann Samuel D. , Miller Richard M. 
Published: December 2022

Introduction:
Injuries to the medial patellofemoral ligament (MPFL) and patellar tendon in isolation are well-documented entities. There is a paucity of literature describing this combination of injuries and treatment of this concomitant injury pattern.

Objective:
The intent of this manuscript was to document the combined injury pattern of a concomitant MPFL rupture and patellar tendon disruption. We also aimed to describe a treatment option for this rarely documented injury pattern.

Materials and Methods:
Our MPFL reconstruction technique utilized a gracilis allograft and 2 biocomposite anchors for the patella. Our patellar tendon repair utilized Ethibond suture in a Krakow stitch fashion, which was subsequently incorporated into the anchors used for the MPFL reconstruction.

Results:
Our patient successfully transitioned through a specific postoperative range of motion protocol by increasing knee flexion 30 degrees every 2 weeks, beginning at 0 to 30 degrees at the first postoperative visit. Our patient was able to straight leg raise by 6 weeks, began formal physical therapy at 8 weeks, and resumed all normal activity at 6 months.

Conclusion:
We demonstrated a novel technique to repair a combined injury of the MPFL and patellar tendon that produced good clinical outcomes through 6 months.
Fostering Resilience in Nursing Through R.E.S.T.
Authors: Rajamohan Santhiny , Chalmers Kristen , Bennett Erin , Brzoza Sandra “Sam” 
Published: December 2022

ABSTRACT:
With about one-third of nurses having expressed an intention to leave the profession or change jobs in 2022, the effects of nursing job stress are evident. For nurses to continue to provide care in high stress, they must practice self-compassion and build resilience. The importance of resilience education and self-compassion for nurses and in nursing education is discussed from a Christian perspective, along with self-care strategies using the R.E.S.T. (Relationship, Exercise, Self-Compassion, Transformative Thinking) framework. Strategies for building resilience for both individuals and organizations are offered.
Elevated serum levels of diamine oxidase, D-lactate and lipopolysaccharides are associated with metabolic-associated fatty liver disease
Authors: Zhang Ruike , Chen Ya-nan , Zhang Jixia , Liu Jing 
Published: December 2022

Background
Studies have suggested an association between metabolic-associated fatty liver disease (MAFLD) and intestinal barrier function. The present study aims to investigate the association between MAFLD and intestinal barrier impairment in humans and identify potential risk factors for MAFLD.

Methods
A total of 491 patients were retrospectively enrolled in this study. The serum levels of diamine oxidase, D-lactate and lipopolysaccharide were measured to evaluate intestinal barrier integrity in patients with and without MAFLD. Binary logistic regression and correlational analyses were conducted to verify the association between MAFLD and serum levels of intestinal barrier biomarkers.

Results
We enrolled 294 patients with MAFLD and 197 patients without MAFLD in this study. Patients with MAFLD had higher serum levels of diamine oxidase, D-lactate and lipopolysaccharide (P < 0.001) than those without MAFLD. Multivariate logistic regression analyses showed that BMI [odds ratio (OR) 1.324; P < 0.001], triglycerides (OR 2.649; P = 0.002), nonesterified fatty acids (OR 1.002; P = 0.011), diamine oxidase (OR 1.149; P = 0.011) and D-lactate (OR 1.221; P < 0.001) were independent risk factors for MAFLD. Additionally, serum levels of diamine oxidase and D-lactate increase as liver steatosis became more severe. MAFLD patients with ≥2 metabolic abnormalities had higher serum levels of lipopolysaccharide (P = 0.034).

Conclusions
MAFLD is associated with intestinal barrier impairment. Diamine oxidase and D-lactate are potential predictors of MAFLD, and their serum levels are related to liver steatosis. Intestinal barrier impairment is related to metabolic disorders in patients with MAFLD.
Efficacy evaluation and prognostic risk factors analysis of precise hepatectomy in the treatment of intermediate and advanced hepatocellular carcinoma
Authors: Zhang Junhong , Zeng Qiang , Zhang Pengfei , Chen Yajie , Cao Jinglin 
Published: December 2022

Background
To investigate the efficacy of precise hepatectomy in the treatment of patients with intermediate and advanced hepatocellular carcinoma and analyze the risk factors affecting prognosis.

Methods
Totally 104 patients with intermediate and advanced hepatocellular carcinoma from January 2018 to January 2019 were enrolled in this retrospective analysis. Of these, four patients lost to follow-up. Logistic regression was conducted to explore the odds ratio (OR) and 95% confidence interval (CI).

Results
Compared with the control group, the precise hepatectomy decreased intraoperative blood loss (331.2928.91 to 203.29 ± 29.34 ml), operation time (198.29 ± 19.38 to 150.28 ± 18.27 min), perioperative blood transfusion volume (376.22 ± 25.93 to 228.29 ± 22.19 ml) (all P < 0.001). Logistic regression analysis of study group showed that hepatitis B infection (OR  = 1.746; 95% CI, 1.068–2.976), P  =  0.021, Child-Pugh classification (OR  =  2.319; 95% CI, 1.428–3.213), P < 0.001, Eastern Cooperative Oncology Group (ECOG) score (OR  =  2.287; 95% CI, 1.098–3.876; P  =  0.013) and Barcelona-Clinic Liver Cancer (BCLC) staging (OR = 2.029; 95% CI, 1.086–3.671; P = 0.022) were independent risk factors for prognosis of the precise hepatectomy.

Conclusion
Hepatitis B virus infection, Child-Pugh grade, ECOG score and BCLC staging grade were the independent risk factors affecting the prognosis of precise hepatectomy.
Geographical region and clinical outcomes of patients with primary biliary cholangitis from Western Europe
Authors: Murillo Perez Carla F. , Gerussi Alessio , Trivedi Palak J. , Corpechot Christophe , van der Meer Adriaan J. , Maria Battezzati Pier , Lindor Keith D. , Nevens Frederik , Kowdley Kris V. , Bruns Tony , Cazzagon Nora , Floreani Annarosa , Tanaka Atsushi , Ma Xiong , Mason Andrew L. , Gulamhusein Aliya , Ponsioen Cyriel Y. , Carbone Marco , Lleo Ana , Mayo Marlyn J. , Dalekos George N. , Gatselis Nikolaos K. , Thorburn Douglas , Verhelst Xavier , Parés Albert , Janssen Harry L.A. , Hirschfield Gideon M. , Hansen Bettina E. , Invernizzi Pietro , Lammers Willem J. ,   on behalf of the GLOBAL PBC Study Group
Published: December 2022

Background and aims
The are geographic variations in the incidence and prevalence of primary biliary cholangitis (PBC). The aim was to explore whether clinical outcomes of patients within Western Europe differ according to geographical region.

Methods
Ursodeoxycholic acid-treated patients from European centers from the Global PBC database diagnosed from 1990 onwards were included. Patients with a time lag > 1 year from diagnosis to start of follow-up were excluded. Differences in baseline characteristics were studied according to North/South and East/West, whereas outcomes (transplant-free survival and decompensation) were studied with center latitude and longitude. Cox regression analyses were adjusted for age, sex, diagnosis year, biochemical markers, and cirrhosis as a time-dependent covariate.

Results
One thousand eight hundred seventy-eight patients were included, and there were no geographical differences in age or sex, with a mean age of 54 years and 89% female patients. Those in North Europe were more often of a moderately advanced/advanced Rotterdam biochemical stage (28.4%) compared with South Europe (20.6%). Additionally, they exhibited higher median alkaline phosphatase (2.0 ×ULN vs. 1.4 ×ULN) and transaminases. In multivariable analysis, there was a significant interaction between center latitude and longitude for decompensation (P < 0.001) and a trend for transplant-free survival, in which the Northwestern area demonstrated an increased risk for poor outcomes as compared to the reference (Paris).

Conclusion
We describe geographic variations in outcomes for patients across Europe from specialist centers in the Global PBC Study Group. Further study is important to explore the potential individual, environmental, and healthcare-related factors that may be contributors.
Perceptions and Use of Safe Sleep Baby Boxes at Hospital Discharge by New Mothers
Authors: Hughes Kimberly , Gill Sara L. , Berndt Andrea 
Published: December 2022

Abstract

Background:
A large community hospital in South Texas began distributing safe sleep baby boxes to reduce sudden unexplained infant death (SUID) in 2017.

Purpose:
To describe safe sleep practices among new mothers who received a safe sleep baby box at hospital discharge.

Methods:
An information sheet containing a link to an online survey was mailed to all women who received a safe sleep baby box prior to discharge from the hospital from January 2018 to January 2019.

Results:

N = 84 women participated. Most reported using the safe sleep baby box only during nap time (n = 62, 88.6%). Only 70.2% of participants reported that baby always slept their back (n = 59). Most reported their baby did not use a pacifier (n = 62, 73.8%), and many reported they were not breastfeeding their baby (n = 38, 45.2%).

Clinical Implications:
Many women were not using the safe sleep baby box as intended and were not following many of the other safe sleep guidelines. Nurses should ask their patients about plans for infant safe sleep after discharge to provide individualized education or recommend specific resources to address the family's needs.
Social Interactions and Institutional Structures that Influence 24-Hour Rooming-in for New Mothers and Newborns in the Hospital Setting
Authors: McRae Maureen J. , Miraglia Robbin 
Published: December 2022

Abstract

Purpose:
To describe the social interactions and institutional structures that influence the consistent practice of 24-hour rooming-in of new mothers and newborns in the hospital setting.

Study Design and Method:
Using an institutional ethnographic design, data were gathered via semistructured interviews and on-unit observations. Data were recorded, transcribed, and analyzed for themes. Study interviews were conducted between February 2020 and June 2021.

Results:
Seven mother–baby nurses were interviewed, and three on-unit observations of 2 hours each were conducted. Analysis of interview data revealed a consensus that Baby-Friendly does not always feel mother-friendly. Three major themes identifying social interactions were identified: the mother as a patient, managing expectations, and inconsistencies in practice. Three themes identified institutional structures that influenced 24-hour rooming-in: rates of induction of labor and cesarean birth, nurse staffing, and monitoring of nursery use.

Clinical Implications:
Our findings provide insights about how the everyday work of 24-hour rooming-in is organized and experienced by nurses on the mother–baby units at the study hospital. Themes highlight specific social interactions and institutional structures that affect the practice and can be used by hospital leaders and educators to develop targeted interventions for ensuring consistent 24-hour rooming-in.
Subchorionic Hemorrhage in the Second and Third Trimesters of Pregnancy: A Review
Authors: Pagan Megan , Monson Joshua , Strebeck Ryan , Edwards Sarah , Magann Everett F. 
Published: December 2022

ImportanceSubchorionic hemorrhage (SCH) in the second and third trimesters of pregnancy can be associated with maternal morbidity and fetal morbidity/mortality. Management of SCH in the second or third trimesters can be complicated, especially in the setting of a large SCH that requires hospitalization and blood transfusion.ObjectiveThe aim of this review is to describe SCH in second and third trimesters, risk factors, diagnosis, maternal and fetal outcomes, and management of this uncommon pregnancy complication.Evidence AcquisitionA PubMed, Web of Science, and CINAHL search was undertaken with no limitations on the number of years searched.ResultsThere were 123 abstracts and/or articles reviewed, with 48 articles being the basis of review. The only known risk factors for SCH are maternal factor deficiency and anticoagulation therapy. The diagnosis is usually made by ultrasound imaging. Subchorionic hemorrhage in second and third trimesters has been associated with several adverse fetal outcomes including preterm birth, preterm prelabor rupture of membranes, fetal growth restriction, fetal demise, and neonatal pulmonary morbidity. There is no proven treatment for SCH, although there are several investigational therapies reported.ConclusionsSubchorionic hemorrhage can be complex and difficult to manage in the second and third trimesters. There are no recommendations or guidelines for management; however, serial growth ultrasounds, umbilical artery Doppler studies, and antenatal fetal testing should be considered particularly if the SCH is large or treatment requires a maternal blood transfusion.RelevanceSubchorionic hemorrhage in the second and third trimester is associated with poor fetal outcomes and maternal morbidity, especially if the SCH is significant.Target AudienceObstetricians and gynecologists, midwives, family physicians.Learning ObjectivesAfter completion of this article, the reader should be better able to identify SCH in the second and third trimesters; describe potential complications associated with SCH; and predict adverse outcomes associated with SCH.