bluuebunny/crossref_metadata_2025_split huggingface dataset:
Job Satisfaction and Extension Modalities Employed by the Extension Professionals in the Occidental Mindoro State College’s Extension Delivery Service
Authors: Declaro-Ruedas Mary Yole Apple , Cruz Merlita P. Dela 
Published: May 2022

The study was conducted to determine the extension modalities employed by the extension professionals, problems encountered in conducting extension service, and their job satisfaction in the extension delivery service.
The study employed descriptive research design. The Minnesota Satisfaction Questionnaire (MSQ) collection instrument was used. The respondents were purposively selected from the list of faculty and staff actively involved in extension service. Descriptive statistics were used to analyse the gathered data.
Result shows the extension modalities were “sometimes” employed by the extension professionals during the conduct of extension activities.
Further, the “highly’ serious problem encountered were lack of extension worker's competencies, change in political leadership , lack of trainings in extension methods and communication skills, and too much academic work in addition to field work. However, they were “highly satisfied” with their extension work.
As the fulfilment of extension professionals in the academe, there is a need to revisit their job satisfaction that could also lead to an improved and effective delivery of extension.
The paper presents a model on job satisfaction that draws on experiences of extension professions that could be applied to early career and continuing professional development in the academe.
Phytochemical Analysis of Some Medicinal Plants Used for the Management of Reproductive Health Care Problems in the West Region in Cameroon
Authors: Tsobou Roger , Lekeufack Martin , Agyingi Lucy Ambang , Anouma’a Mariette , Tiokeng Bertine , Njimeli Patrick Sonkoue , Awouafack Maurice Ducret , Mapongmetsem Pierre-Marie , Patrick Van Damme 
Published: May 2022

Reproductive diseases are conditions that negatively affects human reproductive systems in many countries. Indeed this study was carried out to analyse chemical constituents of some medicinal plants used to treat reproductive organs, diseases in Bamboutos division, West of Cameroon. 45 plants samples were collected from their natural habitats in some villages of the above cited division. Study was conducted according to standard procedures in the laboratory of Organic Chemistry and Natural Substances of the University of Dschang. Polyphenols were revealed in all screening medicinal plant extracts, while, flavonoids were found in most of the studied plant extracts except for those obtained from Dioscorea dumetorum. Triterpens were present in 40 plants, saponins and sterols were respectively found in 33 and 32 plants ; whereas, alkaloids were only present in 15 plants.This work showed that the plants used to alleviate human reproductive ailments in some locality of the West Region in Cameroon are rich in bioactive compounds. These compounds are known to manage human reproductive diseases. Therefore, this finding supported the uses of these plant species for the treatment of human reproductive diseases. Furthermore, appropriate conservation of such valuable medicinal plant species is required.
Association of Tranexamic Acid with GCS in Patients with Traumatic Brain Injury
Authors: Ziad Kamil , Khan Inayat Ali , Shehbaz Lal , Sidhwani Santosh Kumar , Fawad Bina , Fahim Ariba 
Published: May 2022

Background: Traumatic Brain Injury (TBI) occurs due to head injury ranging from simple blow to penetrating injury. TBI refers to a violently produced brain damage that is either blunting or piercing that accelerates or decelerates, resulting in the development of various clinical signs and symptoms such as loss of consciousness or lowered awareness level, entire or partial loss of memory, and various neurological or neuropsychological abnormalities, all of which can lead to disability or death. . As a result, antifibrinolytic drugs like tranexamic acid (TXA) may help to prevent traumatic intra-cranial hemorrhage. The aim of current study was to determine the effect of Tranexamic acid on Glasgow Coma Scale score in TBI patients
Methodology: In this Quasi experimental type of study the 126 patients were recruited from the emergency department of Ziauddin University and Hospital North site who were presented with the traumatic brain injury. Confirmed patients of TBI were distributed into two groups; Tranexamic acid Group: A group of TBI patient received 1 gm. of tranexamic acid infused over ten minutes within three hours of injury along with standard treatment and Placebo Group: A group of TBI patient only received standard treatment.
Results: The mean age of the study subjects was found to be 45.6±18.7 ranged between 18 to 89 years. While assessing the clinical parameters mean temperature recorded is 36.6 ºC, with mean respiratory rate and pulse rate of 20.3 and 91.6 respectively. The comparative analysis of the two treatment groups in which one group got the TXA and other had the usual recommended drugs only with the effectiveness of TXA in term of improvement of GCS score showed highly significant statistical association.
Conclusion: Use of Trenaxamic acid (TXA) helps in improvement of GCS at many intervals of 6 hours, 12 hours and 24 hours as compared to those who received conventional treatment.
RuO2 Supercapacitor Enables Flexible, Safe, and Efficient Optoelectronic Neural Interface
Authors: Karatum Onuralp , Yildiz Erdost , Kaleli Humeyra Nur , Sahin Afsun , Ulgut Burak , Nizamoglu Sedat 
Published: May 2022

AbstractOptoelectronic biointerfaces offer a wireless and nongenetic neurostimulation pathway with high spatiotemporal resolution. Fabrication of low‐cost and flexible optoelectronic biointerfaces that have high photogenerated charge injection densities and clinically usable cell stimulation mechanism is critical for rendering this technology useful for ubiquitous biomedical applications. Here, supercapacitor technology is combined with flexible organic optoelectronics by integrating RuO2 into a donor–acceptor photovoltaic device architecture that facilitates efficient and safe photostimulation of neurons. Remarkably, high interfacial capacitance of RuO2 resulting from reversible redox reactions leads to more than an order‐of‐magnitude increase in the safe stimulation mechanism of capacitive charge transfer. The RuO2‐enhanced photoelectrical response activates voltage‐gated sodium channels of hippocampal neurons and elicits repetitive, low‐light intensity, and high‐success rate firing of action potentials. Double‐layer capacitance together with RuO2‐induced reversible faradaic reactions provide a safe stimulation pathway, which is verified via intracellular oxidative stress measurements. All‐solution‐processed RuO2‐based biointerfaces are flexible, biocompatible, and robust under harsh aging conditions, showing great promise for building safe and highly light‐sensitive next‐generation neural interfaces.
Functional Carbon Nitride Materials in Photo‐Fenton‐Like Catalysis for Environmental Remediation
Authors: Lin Jingkai , Tian Wenjie , Guan Zheyu , Zhang Huayang , Duan Xiaoguang , Wang Hao , Sun Hongqi , Fang Yanfen , Huang Yingping , Wang Shaobin 
Published: May 2022

AbstractAmong various advanced oxidation processes, coupled photocatalysis and heterogeneous Fenton‐like catalysis (known as photo‐Fenton‐like catalysis) to generate highly reactive species for environmental remediation has attracted wide interests. As an emerging metal‐free photocatalyst, graphitic carbon nitride (g‐C3N4, CN) has been recently recognized as a promising candidate to catalyze robustly heterogeneous photo‐Fenton‐like reactions for wastewater remediation. This review summarizes recent progress in fabricating various types of CN‐based catalysts for the photo‐Fenton‐like reaction process. Innovative engineering strategies on the CN matrix are outlined, ranging from morphology control, defect engineering, nonmetal atom doping, organic molecule doping to modification by metal‐containing species. The photo‐Fenton‐like catalytic activities of CN loaded with auxiliary sub‐nanoscale (e.g., quantum dots, organometallic molecules, metal cations, and single atom metals) and nanoscale metal‐based materials are critically evaluated. Hybridization of CN with bandgap‐matching semiconductors for the construction of type‐II and Z‐scheme heterojunctions are also examined. The critical factors (e.g., morphology, dimensionality, light absorption, charge excitation/migration, catalytic sites, H2O2 generation and activation) that determine the performance of CN‐based photocatalysts in Fenton‐like catalysis are systematically discussed. After examining the structure–activity relationship, research perspectives are proposed for further development of CN‐based photocatalysts toward more efficient photo‐Fenton‐like reactions and their application in practical water treatment.
Structural Design and Fabrication of Multifunctional Nanocarbon Materials for Extreme Environmental Applications
Authors: Wu Sijia , Li Huajian , Futaba Don N. , Chen Guohai , Chen Chen , Zhou Kechen , Zhang Qifan , Li Miao , Ye Zonglin , Xu Ming 
Published: May 2022

AbstractExtreme environments represent numerous harsh environmental conditions, such as temperature, pressure, corrosion, and radiation. The tolerance of applications in extreme environments exemplifies significant challenges to both materials and their structures. Given the superior mechanical strength, electrical conductivity, thermal stability, and chemical stability of nanocarbon materials, such as carbon nanotubes (CNTs) and graphene, they are widely investigated as base materials for extreme environmental applications and have shown numerous breakthroughs in the fields of wide‐temperature structural‐material construction, low‐temperature energy storage, underwater sensing, and electronics operated at high temperatures. Here, the critical aspects of structural design and fabrication of nanocarbon materials for extreme environments are reviewed, including a description of the underlying mechanism supporting the performance of nanocarbon materials against extreme environments, the principles of structural design of nanocarbon materials for the optimization of extreme environmental performances, and the fabrication processes developed for the realization of specific extreme environmental applications. Finally, perspectives on how CNTs and graphene can further contribute to the development of extreme environmental applications are presented.
Achieving Ultrahigh‐Rate Planar and Dendrite‐Free Zinc Electroplating for Aqueous Zinc Battery Anodes
Authors: Pu Shengda D. , Gong Chen , Tang Yuanbo T. , Ning Ziyang , Liu Junliang , Zhang Shengming , Yuan Yi , Melvin Dominic , Yang Sixie , Pi Liquan , Marie John‐Joseph , Hu Bingkun , Jenkins Max , Li Zixuan , Liu Boyang , Tsang S. C. Edman , Marrow T. James , Reed Roger C. , Gao Xiangwen , Bruce Peter G. , Robertson Alex W. 
Published: May 2022

AbstractDespite being one of the most promising candidates for grid‐level energy storage, practical aqueous zinc batteries are limited by dendrite formation, which leads to significantly compromised safety and cycling performance. In this study, by using single‐crystal Zn‐metal anodes, reversible electrodeposition of planar Zn with a high capacity of 8 mAh cm−2 can be achieved at an unprecedentedly high current density of 200 mA cm−2. This dendrite‐free electrode is well maintained even after prolonged cycling (>1200 cycles at 50 mA cm−2). Such excellent electrochemical performance is due to single‐crystal Zn suppressing the major sources of defect generation during electroplating and heavily favoring planar deposition morphologies. As so few defect sites form, including those that would normally be found along grain boundaries or to accommodate lattice mismatch, there is little opportunity for dendritic structures to nucleate, even under extreme plating rates. This scarcity of defects is in part due to perfect atomic‐stitching between merging Zn islands, ensuring no defective shallow‐angle grain boundaries are formed and thus removing a significant source of non‐planar Zn nucleation. It is demonstrated that an ideal high‐rate Zn anode should offer perfect lattice matching as this facilitates planar epitaxial Zn growth and minimizes the formation of any defective regions.
Tailoring Oxygen Reduction Reaction Pathway on Spinel Oxides via Surficial Geometrical‐Site Occupation Modification Driven by the Oxygen Evolution Reaction
Authors: An Li , Hu Yang , Li Jianyi , Zhu Jiamin , Sun Mingzi , Huang Bolong , Xi Pinxian , Yan Chun‐Hua 
Published: May 2022

AbstractThe oxygen reduction reaction (ORR) has been demonstrated as a critical technology for both energy conversion technologies and hydrogen peroxide intermediate production. Herein, an in situ oxygen evolution reaction (OER) surface evolution strategy is applied for changing the surface structure of MnCo2O4 oxide with tetrahedral and octahedral cations vacancies to realize reaction pathway switching from 2e− ORR and 4e− ORR. Interestingly, the as‐synthesized MnCo2O4‐pristine (MnCo2O4‐P) with the highest surficial Mn/Co octahedron occupation favors two electrons reaction routes exhibiting high H2O2 selectivity (≈80% and reaches nearly 100% at 0.75 V vs RHE); after surface atoms reconstruction, MnCo2O4‐activation (MnCo2O4‐A) with the largest Mn/Co tetrahedron occupation present excellent ORR performance through the four‐electron pathway with an ultrahigh onset potential and half‐wave potential of 0.78 and 0.92 V, ideal mass activity (MA), and turnover frequencies (TOF) values. Density functional theory (DFT) calculations reveal the concurrent modulations of both Co and Mn by the surface reconstructions, which improve the electroactivity of MnCo2O4‐A toward the 4e− pathway. This work provides a new perspective to building correlation of OER activation–ORR property, bringing detailed understating for reaction route transformation, and thus guiding the development of certain electrocatalysts with specific purposes.
Chiral Mesostructured Carbonate with Vibrational Circular Dichroism
Authors: Huang Maofu , Zhang Xueliang , Han Lu , Che Shunai , Duan Yingying 
Published: May 2022

AbstractThe absorption‐based optical activities (OA) of chiral inorganic materials without the assistance from organic molecules are limited in the plasmon of chiral metallic nanomaterials and the electron transition of chiral semiconductors at the ultraviolet–visible (UV–vis) region. In this work, chiral mesostructured manganese carbonate (CMMC) nano‐dumbbells with hierarchically chiral structures are synthesized, exhibiting vibrational circular dichroism (VCD) signals. CMMC powders are synthesized by a chiral‐molecule‐induced hydrothermal method. Three levels of hierarchical chirality exist in the CMMC, including primary twisted nanoflakes with distorted crystal lattices at the atomic level, secondary stacking of nanoflakes to form a nanoplate, and tertiary arranged nanoplates to form a twisting nano‐dumbbell. Antipodal CMMC samples exhibit antipodal VCD signals at the infrared region (IR) absorption 1400 and 860 cm–1, attributed to vibrational transitions in the asymmetric electric field and selective light harvesting in the hierarchically chiral structures.
Topological Supercavity Resonances in the Finite System
Authors: Huang Lujun , Jia Bin , Chiang Yan Kei , Huang Sibo , Shen Chen , Deng Fu , Yang Tianzhi , Powell David A , Li Yong , Miroshnichenko Andrey E 
Published: May 2022

AbstractAcoustic resonant cavities play a vital role in modern acoustical systems. The ultrahigh quality‐factor resonances are highly desired for some applications such as high‐resolution acoustic sensors and acoustic lasers. Here, a class of supercavity resonances is theoretically proposed and experimentally demonstrated in a coupled acoustic resonator system, arising from the merged bound states in the continuum (BICs) in geometry space. Their topological origin is demonstrated by explicitly calculating their topological charges before and after BIC merging, accompanied by charges annihilation. Compared with other types of BICs, they are robust to the perturbation brought by fabrication imperfection. Moreover, it is found that such supercavity modes can be linked with the Friedrich–Wintgen BICs supported by an entire rectangular (cuboid) resonator sandwiched between two rectangular (or circular) waveguides and thus more supercavity modes are constructed. Then, these coupled resonators are fabricated and such a unique phenomenon—moving, merging, and vanishing of BICs—is experimentally confirmed by measuring their reflection spectra, which show good agreement with the numerical simulation and theoretical prediction of mode evolution. The results may find exciting applications in acoustic and photonics, such as enhanced acoustic emission, filtering, and sensing.
Unravelling Alkali‐Metal‐Assisted Domain Distribution of Quasi‐2D Perovskites for Cascade Energy Transfer toward Efficient Blue Light‐Emitting Diodes
Authors: Cai Wanqing , Ali Muhammad Umair , Liu Ping , He Miao , Zhao Cong , Chen Ziming , Zang Yue , Tang Man‐Chung , Meng Hong , Fu Hongyan , Wei Guodan , Yip Hin‐Lap 
Published: May 2022

AbstractSolution processable quasi‐2D (Q‐2D) perovskite materials are emerging as a promising candidate for blue light source in full‐color display applications due to their good color saturation property, high brightness, and spectral tunability. Herein, an efficient energy cascade channel is developed by introducing sodium bromide (NaBr) in phenyl‐butylammonium (PBA)‐containing mixed‐halide Q‐2D perovskites for a blue perovskite light‐emitting diode (PeLED). The incorporation of alkali metal contributes to the nucleation and growth of Q‐2D perovskites into graded distribution of domains with different layer number <n>. The study of excitation dynamics by transient absorption (TA) spectroscopy confirms that NaBr induces more Q‐2D perovskite phases with small n number, providing a graded energy cascade pathway to facilitate more efficient energy transfer processes. In addition, the nonradiative recombination within the Q‐2D perovskites is significantly suppressed upon Na+ incorporation, as validated by the trap density estimation. Consequently, the optimized blue PeLEDs manifest a peak external quantum efficiency (EQE) of 7.0% emitting at 486 nm with a maximum luminance of 1699 cd m−2. It is anticipated that these findings will improve the understanding of alkali‐metal‐assisted optimization of Q‐2D perovskites and pave the way toward high‐performance blue PeLEDs.
Realizing Negatively Charged Metal Atoms through Controllable d‐Electron Transfer in Ternary Ir1−xRhxSb Intermetallic Alloy for Hydrogen Evolution Reaction
Authors: Lin Zhiping , Xiao BeiBei , Huang Min , Yan Linghui , Wang Zongpeng , Huang Yucong , Shen Shijie , Zhang Qinghua , Gu Lin , Zhong Wenwu 
Published: May 2022

AbstractAlloying noble metals with non‐noble metals is a promising method to fabricate catalysts, with the advantages of reduced noble metal usage and excellent activity. In this work, electron‐abundant Ir/Rh sites, as highly active centers for the hydrogen evolution reaction (HER), are realized by fabricating Ir1−xRhxSb alloys through the arc‐melting method. The electron transfer from Sb to Ir/Rh makes the latter negatively charged, leading to considerably optimized adsorption for active H species during HER. As a result, the Ir1−xRhxSb alloy exhibits outstanding activity for HER, with an optimized overpotential of 22 mV at 10 mA cm–2 and a Tafel slope of 47.6 mV dec–1. This work provides insights into highly active alloys and sheds light on the utilization of electron‐abundant metal atoms.
A CRISPR view of hematopoietic stem cells: Moving innovative bioengineering into the clinic
Authors: Worthington Atesh K. , Forsberg E. Camilla 
Published: May 2022

AbstractClustered regularly interspaced short palindromic repeats (CRISPR)/Cas genome engineering has emerged as a powerful tool to modify precise genomic sequences with unparalleled accuracy and efficiency. Major advances in CRISPR technologies over the last 5 years have fueled the development of novel techniques in hematopoiesis research to interrogate the complexities of hematopoietic stem cell (HSC) biology. In particular, high throughput CRISPR based screens using various “flavors” of Cas coupled with sequencing and/or functional outputs are becoming increasingly efficient and accessible. In this review, we discuss recent achievements in CRISPR‐mediated genomic engineering and how these new tools have advanced the understanding of HSC heterogeneity and function throughout life. Additionally, we highlight how these techniques can be used to answer previously inaccessible questions and the challenges to implement them. Finally, we focus on their translational potential to both model and treat hematological diseases in the clinic.
Long‐term outcomes of patients with conjunctival extranodal marginal zone lymphoma
Authors: Saul Eduardo Edelman , Alderuccio Juan Pablo , Reis Isildinha M. , Zhao Wei , Iyer Sunil G. , Rodriguez Gregor , Desai Amrita , Chapman Jennifer R. , Tse David T. , Markoe Arnold M. , Isrow Derek M. , Lossos Izidore S. 
Published: May 2022

AbstractComprehensive information on clinical features and long‐term outcomes of primary conjunctival extranodal marginal zone lymphoma (PCEMZL) is scarce. We present a large single‐institution retrospective study of 72 patients. The median age was 64 years, and 63.9% were female. Stage I was present in 87.5%. Radiation therapy (RT) alone was the most common treatment (70.8%). Complete response (CR) was 87.5%, and 100% in RT‐treated patients. With a median follow‐up of 6.7 years, relapse/progression and death occurred in 19.4% each, with one relapse within the RT field. The 10‐year progression‐free survival (PFS) and overall survival (OS) were 68.4% (95% CI 52.8%–79.8%) and 89.4% (95% CI 77.4%–95.2%), respectively. The 10‐year rate for time to progression from diagnosis was 22.5% (95% CI 11.6%–35.7%). The 10‐year PFS and OS of MALT‐IPI 0 versus 1–2 were 83.3% versus 51.3%, (p = .022) and 97.6% versus 76.6%, (p = .0052), respectively. The following characteristics were associated with shorter survival: age > 60 years (PFS: HR = 2.93, 95% CI 1.08–7.95; p = .035, OS: HR = 9.07, 95% CI 1.17–70.26; p = .035) and MALT‐IPI 1–2 (PFS: HR = 2.67, 95% CI 1.12–6.31; p = .027, OS: HR = 6.64, 95% CI 1.45–30.37; p = .015). CR following frontline therapy was associated with longer PFS (HR = 0.13, 95% CI 0.04–0.45; p = .001), but not OS. Using the Fine and Gray regression model with death without relapse/progression as a competing risk, RT and CR after frontline therapy were associated with lower risk of relapse (SHR = 0.34, 95% CI 0.12–0.96 p = .041 and SHR = 0.11, 95% CI 0.03–0.36; p < .001, respectively). Patients with PCEMZL treated with frontline RT exhibit excellent long‐term survival, and the MALT‐IPI score appropriately identifies patients at risk for treatment failure.
Preparation of Functionalized Amides Using Dicarbamoylzincs
Authors: Djukanovic Dimitrije , Ganiek Maximilian A. , Nishi Kohei , Karaghiosoff Konstantin , Mashima Kazushi , Knochel Paul 
Published: May 2022

AbstractWe report a new convenient preparation of dicarbamoylzincs of type (R1R2NCO)2Zn by the treatment of ZnCl2and formamides R1R2NCHO with LiTMP in THF (15 °C, 15 min) or by the reaction of formamides R1R2NCHO with TMP2Zn (25 °C, 16 h). This second method tolerates sensitive groups such as an ester, ketone or nitro function. Reaction of these dicarbamoylzincs with allylic, benzylic, aryl, alkenyl bromides, acid chlorides, aldehydes or enones provided various polyfunctional amides in 47–97 % yields.13C NMR characterization of these new carbamoylzinc derivatives is reported.