bluuebunny/crossref_metadata_2025_split huggingface dataset:
Geometric Design and Outcome of Transposition Flaps for Scalp Reconstruction
Authors: Shah Md Shahin , Hamid Md Abdul , Islam Md Hamidul 
Published: November 2022

Background: The scalp is a unique part of the human body and various etiological factors, such as tumor extirpation, avulsion, infection, burns, or trauma, can lead to scalp defects. Primary closure, skin grafting, local flaps, tissue expansion or free tissue transfer is modalities available for scalp reconstruction. Local flap coverage is best option for full thickness loss with exposed bone. Among various local flap transposition flap is reasonable and flexible option with good outcome for scalp reconstruction.
Objective: The purpose of this study was to evaluate the geometric design of transposition flap for scalp reconstruction concerning the dimension of the defect and outcome the surgery.
Methods: This was a prospective observational study, conducted in the Burn & Plastic Surgery department of Rangpur medical college hospital, Rangpur and different private hospitals of Rangpur city over a period of three years from June 2018 to July 2021 through purposive sampling. All aged patients having single full thickness scalp wound with loss of pericranium were included in this study. In all cases transposition flaps were used. All the flaps were elevated through sub galeal lose areolar plane. Flap donor site was covered with split thickness skin graft taken from thigh. Surgical technique, patient factors and outcome were evaluated.
Results: A total 50 patients were operated. The age range was 07-68 years, among them 36% patient were in the age range of 21 – 30 years. 80% patients in this series were male. In this series 64 % patients were construction and electric worker by profession. Electric burn was the main (64%) cause of soft tissue defect of scalp. The majority (46%) of the patients had a wound dimension of 51-70 cm2, smallest was (5x6) = 30cm2 and largest was (9x15) = 135cm2, indicating that extent of soft tissue defects in this series is quite extensive. 12 (24%) patients had complication and all were due to infection, seven patients had infection in flap recipient site, 2 patients had infection in flap donor site and 3 patients developed infection in skin donor site. There was no flap loss in our study.
Conclusion: Sound knowledge of flap geometry and clear evaluation of the defect is mandatory for successful reconstruction of scalp defect. A local transposition flap with donor site skin grafting is reliable option for reconstruction of full thickness scalp defect in most instances.
J Rang Med Col. September 2022; Vol. 7, No. 2:52-57
Knowledge About nCOVID-2019 Among the Population of Palashbari Upazilla in Gaibandha District
Authors: Hossain Sarowat , Alam SM Rowshan , Islam Mahabubul , Begum Munira , Sarker Zakir Hossain , Miah Shah Shahjada , Hanifa Md Abu , Fatema Taslim , Hasan Labib 
Published: November 2022

Background: Novel Corona virus-2019 (nCOVID-2019) is recognized as a major public health threat all over the world. This virus is spreading at a breakneck speed since its emergence from Wuhan, China in December 2019 and it is important to pull all the necessary resources to halt it. The outbreaks of Coronavirus infection among people are always of public health concern especially when they have little knowledge. Most infectious disease preventive campaigns assume that if rational knowledge is given, people's behavior will change and will favor control.
Objective: The study was aimed to assess the public knowledge about nCOVID-2019.
Methods: A descriptive type of cross-sectional study was carried out among the population of Palashbari Upazilla, Gaibandha district from 20 th January 2020 to 20 th February 2020. 1010 respondents were selected conveniently from 5 catchment areas. Data were collected through face-to-face interviews with a pre-tested structured questionnaire. Collected data were entered in the spreadsheet and analyzed in SPSS version 23.
Results: The highest numbers of respondents were in the age group of 15 to 30 years (43.2%). Male and females of were almost equally distributed. 92.9% of the respondents heard the name of 2019-nCoV and 47.6% of them said that it was a respiratory tract infection. 57.5% respondents knew about the sign symptoms but only 26.6% among them could identify all sign symptoms satisfactorily. 40.8% were aware that it was transmitted through the air and only 31.2% knew humans as the source of infection, 19.8% of respondents had no knowledge and others told that wild animals, snakes, bats, cattle, and poultry could transmit the virus. A good percentage of respondents could tell about using masks (85.4%), hand washing (84.75%), avoid touching mouth nose and eyes with the unwashed hand (78.9%), avoid undercooked food (70.6% ), avoid touching poultry and animals (71.2%) and the necessity to quarantine the suspected cases (71.3%), as beneficial for the prevention of Coronavirus infection but they had a lack of knowledge about the treatment (24.52%), 63.5% respondents knew that there was no treatment against Coronavirus infection whereas 11.9% didn’t know about the treatment and only 22.6% had knowledge about the quarantine period.
Conclusion: The study revealed that, though most of the respondents heard the name Coronavirus, people have limited knowledge about transmission, quarantine, and treatment against nCOVID-2019. Health care professionals have to work with enormous effort to control the outbreak of nCOVID-2019.
J Rang Med Col. September 2022; Vol. 7, No. 2:58-62
Algoritma K-Medoids untuk Pengelompokan Produksi Padi dan Beras sebagai Upaya Optimalisasi Ketahanan Pangan di Provinsi Riau
Authors: Luth Fimawahib  , Imam Rangga Bakti  , Asep Supriyanto  
Published: November 2022

Tanaman pangan seperti padi masih menjadi perhatian dunia, termasuk di negara Indonesia khususnya Provinsi Riau. Kendala yang dihadapi Provinsi Riau adalah terbatasnya pengetahuan dalam pengelompokan produksi padi dan beras. Data mining memiliki beberapa algoritma dalam Clustering data, salah satunya K-Medoids. Produksi padi dan beras di Provinsi Riau dalam penelitian ini dikelompokkan menggunakan algoritma K-Medoids dengan menetapkan k sejumlah 2 (dua). Perhitungan manual metode dan implementasi dalam RapidMiner untuk produksi padi dan beras dari tahun 2019 sampai 2021, maka diperoleh Cluster 1 (tinggi) sebanyak 4 kabupaten, sementara Cluster 2 (rendah) sebanyak 8 kabupaten. Hasil ini bisa menjadi informasi bagi pemerintah Provinsi Riau bahwa masih banyak kabupaten yang belum optimal dalam produksi padi dan beras, sehingga pemerintah bisa lebih fokus dalam meningkatkan produksi padi dan beras pada tahun-tahun berikutnya. Evaluasi Cluster menggunakan Davies-Bouldin Index (DBI) dan didapatkn nilai sebesar 0,626, sehingga bisa dikatakan bahwa evaluasi Cluster cukup baik, karena mendekati nol.
PERENCANAAN JALUR SEPEDA DI JALAN SOEKARNO HATTA KOTA MALANG
Authors: Dwi Ratnaningsih  
Published: November 2022

Fasilitas jalur khusus pengguna sepeda sangat diperlukan untuk keamanan dan kenyamanan bersepeda Saat ini minat masyarakat untuk bersepeda sangat tinggi baik untuk aktifitas olahraga, sekolah maupun ke kantor. Ruas Jalan Soekarno Hatta Kota Malang merupakan jalan yang mempunyai volume lalu lintas yang tinggi hal ini disebabkan disekitar jalan Soekarno Hatta merupakan daerah perumahan dan kawasan kampus Universitas Brawijaya dan kampus Politeknik Negeri Malang. Bagi pengguna sepeda jalan Soekarno Hatta merupakan jalur yang kurang nyaman karena belum ada jalur khusus untuk sepeda.
Penelitian ini bertujuan merencanakan studi jalur sepeda di ruas jalan Soekarno Hatta Kota Malang sehingga pengguna sepeda dapat bersepeda dengan aman, nyaman dan tidak mengganggu kinerja ruas jalan Soekarno Hatta. Data primer yang dibutuhkan antara lain: volume lalu lintas, jumlah sepeda, geometrik jalan, kecepatan,rambu dan marka. Data Sekunder yang dibutuhkan antara lain : jumlah penduduk kota malang, peta lokasi.
Berdasarkan analisa sepeda yang melewati jalan Soekarno Hatta keperuntukkannya adalah untuk olahraga dan bukan untuk kargo maka jalur sepeda didesain satu lajur yang terletak di sisi kiri dan sisi kanan badan jalan dan dipisahkan dengan marka dengan lebar 1,20
Analysis of influencing factors for prognosis of patients with ventricular septal perforation: A single-center retrospective study
Authors: Duan Ming-Xuan , Zhao Xi , Li Shao-Lin , Tao Jun-Zhong , Li Bo-Yan , Meng Xin-Guo , Dai Dong-Pu , Lu Yan-Yu , Yue Zhen-Zhen , Du Yang , Rui Zi-Ao , Pang Shuo , Zhou Yuan-Hang , Miao Guang-Rui , Bai Lin-Peng , Zhang Qing-Yang , Zhao Xiao-Yan 
Published: November 2022

BackgroundVentricular septal rupture (VSR) is a type of cardiac rupture, usually complicated by acute myocardial infarction (AMI), with a high mortality rate and often poor prognosis. The aim of our study was to investigate the factors influencing the long-term prognosis of patients with VSR from different aspects, comparing the evaluation performance of the Gensini score, Sequential Organ Failure Assessment (SOFA) score and European Heart Surgery Risk Assessment System II (EuroSCORE II) score systems.MethodsThis study retrospectively enrolled 188 patients with VSR between Dec 9, 2011 and Nov 21, 2021at the First Affiliated Hospital of Zhengzhou University. All patients were followed up until Jan 27, 2022 for clinical data, angiographic characteristics, echocardiogram outcomes, intraoperative, postoperative characteristics and major adverse cardiac events (MACEs) (30-day mortality, cardiac readmission). Cox proportional hazard regression analysis was used to explore the predictors of long-term mortality.ResultsThe median age of 188 VSR patients was 66.2 ± 9.1 years and 97 (51.6%) were males, and there were 103 (54.8%) patients in the medication group, 34 (18.1%) patients in the percutaneous transcatheter closure (TCC) group, and 51 (27.1%) patients in the surgical repair group. The average follow-up time was 857.4 days. The long-term mortality of the medically managed group, the percutaneous TCC group, and the surgical repair group was 94.2, 32.4, and 35.3%, respectively. Whether combined with cardiogenic shock (OR 0.023, 95% CI 0.001–0.054, P = 0.019), NT-pro BNP level (OR 0.027, 95% CI 0.002–0.34, P = 0.005), EuroSCORE II (OR 0.530, 95% CI 0.305–0.918, P = 0.024) and therapy group (OR 3.518, 95% CI 1.079–11.463, P = 0.037) were independently associated with long-term mortality in patients with VSR, and this seems to be independent of the therapy group. The mortality rate of surgical repair after 2 weeks of VSR was much lower than within 2 weeks (P = 0.025). The cut-off point of EuroSCORE II was determined to be 14, and there were statistically significant differences between the EuroSCORE II &lt; 14 group and EuroSCORE II≥14 group (HR = 0.2596, 95%CI: 0.1800–0.3744, Logrank P &lt; 0.001).ConclusionPatients with AMI combined with VSR have a poor prognosis if not treated surgically, surgical repair after 2 weeks of VSR is a better time. In addition, EuroSCORE II can be used as a scoring system to assess the prognosis of patients with VSR.
Influence of COVID-19 restrictions on student satisfaction with undergraduate pathology teaching in an Australian University
Authors: Rodrigo Chaturaka , Herbert Cristan , Saunders Darren , Thomas Shane , Polly Patsie 
Published: November 2022

IntroductionAlmost three years into the COVID-19 pandemic, it is important to reflect on student perceptions of online teaching, and more specifically, if mobility restrictions imposed as public health measures significantly influenced how students perceived online teaching. The aim of this study was to investigate if student perceptions of teaching quality of undergraduate courses would differ when evaluated at times of increasing or relaxing COVID-related mobility restrictions.MethodsWe compared student feedback for two third-year undergraduate Pathology courses taken as part of a Bachelor of Medical Sciences / Science degree in an Australian University from 2019 to 2021. Quantitative feedback on five domains (overall satisfaction, belongingness within a learning community, satisfaction with assessments, adequacy of learning resources, satisfaction with teacher feedback) were categorized into groups based on calendar year or prevailing COVID restrictions (times with no, increasing or relaxing restrictions), and compared. There were no significant changes to the course content during this time, but face-to-face teaching in 2019 changed to predominantly online teaching in 2020 and 2021.ResultsFeedback scores were significantly better (p &lt; 0.017) at times of increased COVID restrictions compared to times with relaxing COVID restrictions across all five domains assessed. Interestingly, when grouped by calendar years (instead of prevailing COVID restrictions), there were mostly no significant differences in the feedback scores, despite the shift to online teaching in 2020/21.ConclusionAt times of increasing mobility restrictions, students may appreciate the consistency offered by well-structured online teaching but when restrictions are relaxed, online-only teaching may not meet their expectations. The teaching methods need to adapt to prevailing situation by focusing on more hands on and face-to-face teaching when circumstances allow it.
Does aerobic exercise reduce NASH and liver fibrosis in patients with non-alcoholic fatty liver disease? A systematic literature review and meta-analysis
Authors: Houttu Veera , Bouts Julia , Vali Yasaman , Daams Joost , Grefhorst Aldo , Nieuwdorp Max , Holleboom Adriaan G. 
Published: November 2022

BackgroundExercise is an effective strategy for the prevention and regression of hepatic steatosis in patients with non-alcoholic fatty liver disease (NAFLD), but it is unclear whether it can reduce advanced stages of NAFLD, i.e., steatohepatitis and liver fibrosis. Furthermore, it is not evident which modality of exercise is optimal to improve/attenuate NAFLD.ObjectivesThe aim is to systematically review evidence for the effect of aerobic exercise (AE) on NAFLD, in particular non-alcoholic steatohepatitis (NASH) and liver fibrosis.MethodsA systematic literature search was conducted in Medline and Embase. Studies were screened and included according to predefined criteria, data were extracted, and the quality was assessed by Cochrane risk of bias tools by two researchers independently according to the protocol registered in the PROSPERO database (CRD42021270059). Meta-analyses were performed using a bivariate random-effects model when there were at least three randomized intervention studies (RCTs) with similar intervention modalities and outcome.ResultsThe systematic review process resulted in an inclusion a total of 24 studies, 18 RCTs and six non-RCTs, encompassing 1014 patients with NAFLD diagnosed by histological or radiological findings. Studies were grouped based on the type of AE: moderate-intensity continuous training (MICT) and high-intensity interval training (HIIT). A total of twelve meta-analyses were conducted. Compared to controls, MICT resulted in a mean difference (MD) in the NAFLD biomarkers alanine transaminase (ALT) and aspartate aminotransferase (AST) of -3.59 (CI: -5.60, -1.59, p&lt;0.001) and -4.05 (CI: -6.39, -1.71, p&lt;0.001), respectively. HIIT resulted in a MD of -4.31 (95% CI: -9.03, 0.41, p=0.07) and 1.02 (95% CI: -6.91, 8.94, p=0.8) for ALT and AST, respectively. Moreover, both AE types compared to controls showed a significantly lower magnetic resonance spectroscopy (MRS) determined liver fat with a MD of -5.19 (95% CI: -7.33, -3.04, p&lt;0.001) and -3.41 (95% CI: -4.74, -2.08, p&lt;0.001), for MICT and HIIT respectively. MICT compared to controls resulted in a significantly higher cardiorespiratory fitness (MD: 4.43, 95% CI: 0.31, 8.55, p=0.03).ConclusionLiver fat is decreased by AE with a concomitant decrease of liver enzymes. AE improved cardiorespiratory fitness. Further studies are needed to elucidate the impact of different types of AE on hepatic inflammation and fibrosis.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/, identifier (CRD42021270059).
Secular increase in the prevalence of gestational diabetes and its associated adverse pregnancy outcomes from 2014 to 2021 in Hebei province, China
Authors: Tian Mei-Ling , Du Li-Yan , Ma Guo-Juan , Zhang Ting , Ma Xu-Yuan , Zhang Ying-Kui , Tang Zeng-Jun 
Published: November 2022

ObjectiveWe aimed to investigate the secular prevalence of gestational diabetes mellitus (GDM) and evaluate its adverse pregnancy outcomes among pregnant women in Hebei province, China.MethodsWe analyzed the data from the monitoring information management system for pregnant women in 22 hospitals of Hebei province, China. In this study, 366,212 individuals with singleton live births from 2014 to 2021 were included, of whom 25,995 were diagnosed with gestational diabetes. We described the incidence of common complications and further analyzed the clinical characteristics in GDM patients and the relationship between GDM and adverse pregnancy outcomes.ResultsThe top 3 pregnancy complications in Hebei province are anemia, gestational hypertension, and GDM. The average incidence of GDM was 7.10% (25,995/366,212). The incidence rate of GDM significantly increased from 2014 to 2021 (χ2trend = 7,140.663, P &lt; 0.001). The top 3 regions with GDM incidence were Baoding (16.60%), Shijiazhuang (8.00%), and Tangshan (3.80%). The incidence of GDM in urban pregnant women (10.6%) is higher than that in rural areas (3.7%).The difference between the GDM and Non-GDM groups was statistically significant in terms of maternal age, gravidity, parity, education level, and incidence of pregnancy complications (gestational hypertension, heart diseases, and anemia) (P &lt; 0.05). GDM individuals were at significantly increased risk of most assessed adverse pregnancy outcomes, including premature delivery, Cesarean delivery, uterine inertia, neonatal intensive care unit (NICU) admission, Apgar (activity-pulse-grimace-appearance-respiration) score at 1 min, and macrosomia (P &lt; 0.05). The multivariate logistic regression analysis showed that GDM was an independent risk factor in terms of premature birth, Cesarean delivery, uterine inertia, placental abruption, NICU admission, and macrosomia.ConclusionThe risk of adverse pregnancy outcome in pregnant women with GDM is significantly increased. In order to reduce the occurrence of adverse pregnancy outcomes, effective interventions are needed.
Blue carbon ecosystem monitoring using remote sensing reveals wetland restoration pathways
Authors: Lanceman Dana , Sadat-Noori Mahmood , Gaston Troy , Drummond Christopher , Glamore William 
Published: November 2022

In an era of climate and biodiversity crises, ecosystem rehabilitation is critical to the ongoing wellbeing of humans and the environment. Coastal ecosystem rehabilitation is particularly important, as these ecosystems sequester large quantities of carbon (known in marine ecosystems as “blue carbon”) thereby mitigating climate change effects while also providing ecosystem services and biodiversity benefits. The recent formal accreditation of blue carbon services is producing a proliferation of rehabilitation projects, which must be monitored and quantified over time and space to assess on-ground outcomes. Consequently, remote sensing techniques such as drone surveys, and machine learning techniques such as image classification, are increasingly being employed to monitor wetlands. However, few projects, if any, have tracked blue carbon restoration across temporal and spatial scales at an accuracy that could be used to adequately map species establishment with low-cost methods. This study presents an open-source, user-friendly workflow, using object-based image classification and a random forest classifier in Google Earth Engine, to accurately classify 4 years of multispectral and photogrammetrically derived digital elevation model drone data at a saltmarsh rehabilitation site on the east coast of Australia (Hunter River estuary, NSW). High classification accuracies were achieved, with &gt;90% accuracy at 0.1 m resolution. At the study site, saltmarsh colonised most suitable areas, increasing by 142% and resulting in 56 tonnes of carbon sequestered, within a 4-year period, providing insight into blue carbon regeneration trajectories. Saltmarsh growth patterns were species-specific, influenced by species’ reproductive and dispersal strategies. Our findings suggested that biotic factors and interactions were important in influencing species’ distributions and succession trajectories. This work can help improve the efficiency and effectiveness of restoration planning and monitoring at coastal wetlands and similar ecosystems worldwide, with the potential to apply this approach to other types of remote sensing imagery and to calculate other rehabilitation co-benefits. Importantly, the method can be used to calculate blue carbon habitat creation following tidal restoration of coastal wetlands.
Whole genome sequencing of the fast-swimming Southern bluefin tuna (Thunnus maccoyii)
Authors: Zhao Xiaomeng , Huang Yu , Bian Chao , You Xinxin , Zhang Xinhui , Chen Jieming , Wang Min , Hu Cancan , Xu Yun , Xu Junmin , Shi Qiong 
Published: November 2022

The economically important Southern bluefin tuna (Thunnus maccoyii) is a world-famous fast-swimming fish, but its genomic information is limited. Here, we performed whole genome sequencing and assembled a draft genome for Southern bluefin tuna, aiming to generate useful genetic data for comparative functional prediction. The final genome assembly is 806.54 Mb, with scaffold and contig N50 values of 3.31 Mb and 67.38 kb, respectively. Genome completeness was evaluated to be 95.8%. The assembled genome contained 23,403 protein-coding genes and 236.1 Mb of repeat sequences (accounting for 29.27% of the entire assembly). Comparative genomics analyses of this fast-swimming tuna revealed that it had more than twice as many hemoglobin genes (18) as other relatively slow-moving fishes (such as seahorse, sunfish, and tongue sole). These hemoglobin genes are mainly localized in two big clusters (termed as “MNˮ and “LAˮ respectively), which is consistent with other reported fishes. However, Thr39 of beta-hemoglobin in the MN cluster, conserved in other fishes, was mutated as cysteine in tunas including the Southern bluefin tuna. Since hemoglobins are reported to transport oxygen efficiently for aerobic respiration, our genomic data suggest that both high copy numbers of hemoglobin genes and an adjusted function of the beta-hemoglobin may support the fast-swimming activity of tunas. In summary, we produced a primary genome assembly and predicted hemoglobin-related roles for the fast-swimming Southern bluefin tuna.