bluuebunny/crossref_metadata_2025_split huggingface dataset:
OWL ontology evolution: understanding and unifying the complex changes
Authors: Torres da Silva Viviane , dos Santos Jéssica Soares , Thiago Raphael , Soares Elton , Guerreiro Azevedo Leonardo 
Published: November 2022

AbstractKnowledge-based systems and their ontologies evolve due to different reasons. Ontology evolution is the adaptation of an ontology and the propagation of these changes to dependent artifacts such as queries and other ontologies. Besides identifying basic/simple changes, it is imperative to identify complex changes between two versions of the same ontology to make this adaptation possible. There are many definitions of complex changes applied to ontologies in the literature. However, their specifications across works vary both in formalization and textual description. Some works also use different terminologies to refer to a change, while others use the same vocabulary to refer to distinct changes. Therefore, there is a lack of a unified list of complex changes. The main goals of this paper are: (i) present the primary documents that identify complex changes; (ii) provide critical analyses about the set of the complex changes proposed in the literature and the documents mentioning them; (iii) provide a unified list of complex changes mapping different sets of complex changes proposed by several authors; (iv) present a classification for those complex changes; and (v) describe some open directions of the area. The mappings between the complex changes provide a mechanism to relate and compare different proposals. The unified list is thus a reference for the complex changes published in the literature. It may assist the development of tools to identify changes between two versions of the same ontology and enable the adaptation of artifacts that depend on the evolved ontology.
High-metabolism Infrastructure and the Scrap Industry in Urban China
Authors: Liebman Adam 
Published: November 2022

AbstractRapid urbanization in 21st-century China has been fraught with contested demolition, overdevelopment and shoddy infrastructure with short lifespans. By viewing this infrastructure as having “high metabolism” and examining the urban scrap trade that is fuelled by its material outputs, this article challenges a common assumption that such a form of urbanization is merely wasteful and problematic. Crucially, such urbanization also puts rural migrants and scrap into motion in a way that helps to reproduce its form. This occurs by generating socio-material nodes of scrap trading wherein migrants make the most of temporarily stable situations with entrepreneurialism. The nodes are spaces of “suspension” shaped by challenges including cheap rental housing that is often targeted for demolition and frequent harassment from the authorities. However, the challenges do not prevent scrap traders from caring for kin, attending to human sentiments and sometimes achieving social mobility.
Materializing the digital landscape: the cinema–ecology complex and Chinese fantasy media
Authors: Tan Jia 
Published: November 2022

AbstractContemporary cinema and media studies are marked by a materialist turn that highlights material elements, such as objects, non-human agencies, the environment and places on and off screen, as well as the materiality of media productions and consumption. This article expands on the important scholarship of “materialist” media studies as well as existing ecocinema scholarship by stressing the materiality of digital landscapes in contemporary Chinese fantasy (orqihuanandxuanhuan) film and television works that have gained significant popularity in China and Hong Kong. Specifically, this article examines the animist landscape in film and television adaptions ofEternal Love, a fantasy romance television serial that loosely draws on Daoist mythology. Focusing on the material aspects of digital landscapes of Chinese fantasy cinema, the article develops the notion of the “cinema–ecology complex” to address the materiality of digital landscapes, the cinematic footprint of digitally enhanced landscapes through location shooting and the consumption of landscapes as scenic spots, includingdakapractices, in film studio cities and related film-induced tourism. Ultimately, this article calls for a textual–infrastructural approach in cinema and media studies, which tends to reorient to the infrastructural aspects of media production, distribution and consumption.
Embedding the silver thread in all-age psychological services: training and supervising younger therapists to deliver CBT for anxiety or depression to older people with multi-morbidity
Authors: Charlesworth Georgina 
Published: November 2022

Abstract
Providers of cognitive behavioural therapy (CBT) in adult mental health services in the UK are expected to deliver therapy suitable for adults of all ages. However, older people commonly present with co-morbidities that challenge delivery of single-diagnosis CBT protocols. Added to this, the difference in age between therapy-provider and service-user can compromise collaboration. In this paper, I consider two key areas of relevance for training and supervising CBT therapists for work with older people, namely multi-morbidities and intergenerational relations. The evolving evidence base for CBT with older people is summarised and a commentary provided on previous ‘old age’ case studies from the Cognitive Behaviour Therapist (tCBT). Strategies for collaborative relationships are discussed, as are strategies for ‘embedding the silver thread’. I conclude with recommendations for future directions for CBT training and supervision.

Key learning aims

(1)
To be aware that any differences in working with older people are not due to age per se, but factors such as cohort differences and multi-morbidity.

(2)
To reflect on case examples of CBT with older people.

(3)
To learn strategies for developing collaborative relationships across an intergenerational divide.
Addressing the accountability void: War crimes against persons with disabilities
Authors: Pons William I. , Lord Janet E. , Stein Michael Ashley 
Published: November 2022

AbstractAcademics rarely raise the need to consider persons with disabilities when preventing, investigating and prosecuting international humanitarian law (IHL) violations. Worse still, no actual attempts have been made to include a disability perspective into practical guidance and monitoring mechanisms. This article addresses that void by laying out how existing yet unutilized IHL obligations can be leveraged to repress and suppress disability-based IHL violations. In doing so, the article will detail how fact-finding approaches, criminal investigative processes and reporting methods for IHL violations can be inclusive of persons with disabilities and thus more appropriately address the endemic under-representation of a disability perspective in the planning and execution of military operations during armed conflict and the specific crimes they thereby suffer. Additionally, this article will articulate concrete changes that should be made to international criminal law procedures for prosecuting war crimes to provide recognition and accountability for disability-based IHL violations, as has been done for violations against women and children. Finally, this article will diagnose the state of the law to address any legal challenges or hurdles that may hamper the inclusion of a disability perspective in fulfilling the IHL obligation to reduce and address violations of humanitarian law.
Can Nature Hold Rights? It's Not as Easy as You Think
Authors: Kurki Visa A.J. 
Published: November 2022

AbstractThe Rights of Nature movement has recently achieved significant successes in using legal personhood as a tool for environmental protection. Perhaps most famously, the Whanganui River in Aotearoa New Zealand was accorded legal personhood in 2017. These kinds of development have attracted plenty of scholarly interest, but few have scrutinized a foundational underlying question: Can natural areas, such as rivers, or other non-sentient natural entities actually be legal persons?The case of the Whanganui River is an example of the direct legal personhood model: it purports to grant legal rights to the river directly. Some other jurisdictions have set up legal persons to administer rivers, without declaring the rivers themselves to be legal persons: the indirect legal personhood model. This article offers legal-philosophical arguments for why legal personhood cannot be attributed to rivers directly.Normally, legal persons can hold claim-rights and be legally wronged. Some legal persons, such as human adults, can also be held legally responsible and exercise legal competences by entering into contracts. Natural entities cannot do any of these things. Hence, they cannot be legal persons directly; rather, their putative direct legal personhood will collapse into indirect legal personhood. Hence, treating natural entities as direct legal persons amounts only to a legal fiction. Such fictions may be justified for symbolic reasons. However, if environmental protection requires setting up a legal person to protect a natural entity, such protection in most cases can be realized without claiming that the natural entity itself would have become a legal person.
Fragen und Antworten zur Logopädieprüfung:
Authors: Eichel Hans Werner 
Published: November 2022

Für alle Logopäd_innen, klinische Linguist_innen und Sprachheilpädagog_innen ist es auch in der 3. Auflage das optimale Werkzeug, um sich auf die Prüfung in den medizinischen Fächern vorzubereiten. Es enthält Fragen und Antworten zu den prüfungsrelevanten Inhalten von:
•Hals-Nasen-Ohren-Heilkunde
•Phoniatrie
•Audiologie und Pädaudiologie
•Neurologie und Psychiatrie
Die 3. Auflage ist vollständig überarbeitet und erweitert:
•Teil 1: HNO-Heilkunde: Aktualisierung der therapeutischen Hinweise
•Teil 2: Phoniatrie: Aufnahme neuer Störungsbilder und neuer Therapieformen, Berücksichtigung neuer Leitlinien und Definitionen
•Teil 4: Neurologie und Psychiatrie Aufnahme von Fragen zur Kinderpsychiatrie/Kinderneurologie
•Querverweise zwischen den einzelnen Kapiteln
•Hinweise auf Zugehörigkeit zu den einzelnen Prüfungsteilen •Berücksichtigung neuer Definitionen nach den Leitlinien der AVWS
•Fragen zu Anatomie und Physiologie, die nach der LogAPrO innerhalb der klinischen Fächer geprüft werden sollen
Auch die Prüfer_innen und Dozent_innen an den Berufsfachschulen nutzen das Buch zur Prüfungsvorbereitung oder als Repetitorium wie auch zur Anregung, Fragen für Klausuren und mündliche Prüfungen zu entwickeln.
Der Autor Dr. med. Hans Werner Eichel ist seit 2007 als fachärztlicher Leiter und Dozent an der Logopädieschule -Baden-Baden tätig. Er ist Facharzt für Hals-Nasen-Ohren-Heilkunde sowie Stimm- und Sprachstörungen in Baden-Baden. Bereits während seiner klinisch-phoniatrischen Tätigkeit befasste er sich mit der Ausbildung von angehenden Logopädinnen und Logopäden.
Raspberry Pi Reflector (RPR): A Low‐Cost Water‐Level Monitoring System Based on GNSS Interferometric Reflectometry
Authors: Karegar Makan A. , Kusche Jürgen , Geremia‐Nievinski Felipe , Larson Kristine M. 
Published: November 2022

AbstractAlthough reflectometry is not the primary application of Global Positioning System (GPS) and similar Global Navigation Satellite Systems (GNSS), fast‐growing GNSS tracking networks has led to the emergence of GNSS interferometric reflectometry technique for monitoring surface changes such as water level. However, scientific‐grade or geodetic GNSS instruments are expensive, which is a limiting factor for their prompt and more widespread deployment as a dedicated environmental sensor. We present a prototype called Raspberry Pi Reflector (RPR) that includes a low‐cost and low‐maintenance single‐frequency GPS module and a navigation antenna connected to an inexpensive Raspberry Pi microcomputer. A unit has been successfully operating for almost 2 years since March 2020 in Wesel (Germany) next to the Rhine river. Sub‐daily and daily water levels are retrieved using spectral analysis of reflection data. The river level measurements from RPR are compared with a co‐located river gauge. We find an Root‐Mean‐Square Error (RMSE) of 7.6 cm in sub‐daily estimates and 6 cm in daily means of river level. In August 2021, we changed the antenna orientation from upright to sideways facing the river. The RMSE reduced to 3 cm (sub‐daily) and 1.5 cm (daily) with the new orientation. While satellite radar altimetry techniques have been utilized to monitor water levels with global coverage, their measurements are associated with moderate uncertainties and temporal resolution. Therefore, such low‐cost and high‐precision instruments can be paired with satellite data for calibrating, validating and modeling purposes. These instruments are financially (<US$ 150 as of November 2021) and technically accessible worldwide.
Ecological Response to Climate Change Across China From Combined Soil Temperature and Moisture Changes
Authors: Li Mingxing , Ma Zhuguo , Wu Peili , Liu Jiandong , Lv Meixia , Yang Qing , Han Yunhuan 
Published: November 2022

AbstractA coupled soil temperature (ST) and moisture (SM) balance reflects a synthetic climate regime, having huge ecological impacts. This paper used ST and SM data from the European Center for Medium‐Range Weather Forecasts climate reanalysis‐Land and the Coupled Model Intercomparison Project Phase 6 and leaf area index (LAI) data from the Global Land Surface Satellite Product Suite. The focus was on understanding joint ST‐SM changes and the resulting ecological response across China. The results show that during 2000–2020, 24.5% of the land area in China experienced a warming‐drying trend resulting in a 9.7% LAI decrease, while 6.4% of the area experienced a warming‐wetting trend leading to an 8.6% LAI increase. During 2015–2100, 30.6% of the land area in China will be warmer and drier, while 55.2% of the area will be warmer but wetter across three shared socioeconomic pathways (SSP126, 245, and 585). Superimposed on the long‐term trends, there are also significant spatiotemporal variabilities in ST and SM on annual to decadal timescales. The LAI also showed substantial short‐term fluctuations in both typical regions and ecosystems despite consistent long‐term increases. Our findings suggest that ecosystems could be impaired on annual to decadal scales by adverse soil conditions in the twenty‐first century, but in terms of long‐term trends, ecosystems may be resilient partly because of the compensating effects of global warming and regional hydrological changes. Impact studies should thus focus more on annual to decadal soil‐ecosystem anomalous events.
Global Electromagnetic Disturbances Caused by the Eruption of the Tonga Volcano on 15 January 2022
Authors: Gavrilov B. G. , Poklad Y. V. , Ryakhovsky I. A. , Ermak V. M. , Achkasov N. S. , Kozakova E. N. 
Published: November 2022

AbstractThe study is devoted to the analysis of geomagnetic field disturbances and the response of the Schumann resonance (SR) during the eruption of the Tonga volcano in 2022. The data on geomagnetic field variations at distances from 800 to 15,000 km from the volcano according to the INTERMAGNET network and parameters of SR signals recorded at Mikhnevo Observatory in Russia were used. The source of global geomagnetic disturbances are acoustic–gravity waves (AGWs), which caused changes in ionospheric conductivity, values of ionospheric currents, and the geomagnetic field. The propagation velocity of magnetic disturbances 263 ± 5 m/s, corresponding to the AGWs velocity, was determined and an independent estimate of the time of the eruption phase that caused the generation of the atmospheric wave (4:14 ± 10 UT) was obtained. A new method of processing the results of measurements of SR disturbance with a time resolution of 5 min instead of the usual 10–15 min allowed not only to detect but also to study this phenomenon in detail. The peculiarities of signals related to the number and energy of lightning discharges were revealed. Synchronous measurements of SR signals and geomagnetic field variations in a single observatory for the first time allowed to obtain an independent estimate of the eruption time and the electromagnetic disturbance propagation rate.
Hydrodynamics of Meander Bends in Intertidal Mudflats: A Field Study From the Macrotidal Yangkou Coast, China
Authors: Gao Chao , Finotello Alvise , D’Alpaos Andrea , Ghinassi Massimiliano , Carniello Luca , Pan Yupeng , Chen Dezhi , Wang Ya Ping 
Published: November 2022

AbstractMeandering channels are ubiquitous features in intertidal mudflats and play a key role in the eco‐morphosedimentary evolution of such landscapes. However, the hydrodynamics and morphodynamic evolution of these channels are poorly known, and direct flow measurements are virtually nonexistent to date. Here, we present new hydroacoustic data collected synchronously at different sites along a mudflat meander located in the macrotidal Yangkou tidal flat (Jiangsu, China) over an 8‐day period. The studied bend exhibits an overall dominance of flood flows, with velocity surges of about 0.8 m/s occurring immediately below the bankfull stage during both ebb and flood tides. Unlike salt‐marsh channels, velocities attain nearly constant, sustained values as long as tidal flows remain confined within the channel and reduce significantly during overbank stages. In contrast, curvature‐induced cross‐sectional flows are more pronounced during overbank stages. Thus, a phase lag exists between streamwise and cross‐stream velocity maxima, which limits the transfer of secondary flows and likely hinders the formation of curvature‐induced helical flows along the entire meander length. Our results support earlier suggestions that the morphodynamics of intertidal mudflat meanders does not strongly depend on curvature‐induced helical flows and is most likely driven by high velocities and sustains seepage flows at late‐ebb stages, as well as by other tidally‐mediated processes such as waves and intense rainfall events. By unraveling complex flow structures and intertwined morphodynamic processes, our results provide the first step toward a better understanding of intertidal mudflat meanders, with relevant implications for their planform characteristics and dynamic evolution.
Isocitrate dehydrogenase 1 mutation drives leukemogenesis by PDGFRA activation due to insulator disruption in acute myeloid leukemia (AML)
Authors: Steinhäuser Sophie , Silva Patricia , Lenk Lennart , Beder Thomas , Hartmann Alina , Hänzelmann Sonja , Fransecky Lars , Neumann Martin , Bastian Lorenz , Lipinski Simone , Richter Kathrin , Bultmann Miriam , Hübner Emely , Xia Shuli , Röllig Christoph , Vogiatzi Fotini , Schewe Denis Martin , Yumiceba Veronica , Schultz Kristin , Spielmann Malte , Baldus Claudia Dorothea 
Published: November 2022

AbstractAcute myeloid leukemia (AML) is characterized by complex molecular alterations and driver mutations. Elderly patients show increased frequencies of IDH mutations with high chemoresistance and relapse rates despite recent therapeutic advances. Besides being associated with global promoter hypermethylation, IDH1 mutation facilitated changes in 3D DNA-conformation by CTCF-anchor methylation and upregulated oncogene expression in glioma, correlating with poor prognosis. Here, we investigated the role of IDH1 p.R132H mutation in altering 3D DNA-architecture and subsequent oncogene activation in AML. Using public RNA-Seq data, we identified upregulation of tyrosine kinase PDGFRA in IDH1-mutant patients, correlating with poor prognosis. DNA methylation analysis identified CpG hypermethylation within a CTCF-anchor upstream of PDGFRA in IDH1-mutant patients. Increased PDGFRA expression, PDGFRA-CTCF methylation and decreased CTCF binding were confirmed in AML CRISPR cells with heterozygous IDH1 p.R132H mutation and upon exogenous 2-HG treatment. IDH1-mutant cells showed higher sensitivity to tyrosine kinase inhibitor dasatinib, which was supported by reduced blast count in a patient with refractory IDH1-mutant AML after dasatinib treatment. Our data illustrate that IDH1 p.R132H mutation leads to CTCF hypermethylation, disrupting DNA-looping and insulation of PDGFRA, resulting in PDGFRA upregulation in IDH1-mutant AML. Treatment with dasatinib may offer a novel treatment strategy for IDH1-mutant AML.
Marine bacteroidetes use a conserved enzymatic cascade to digest diatom β-mannan
Authors: Beidler Irena , Robb Craig S , Vidal-Melgosa Silvia , Zühlke Marie-Katherin , Bartosik Daniel , Solanki Vipul , Markert Stephanie , Becher Dörte , Schweder Thomas , Hehemann Jan-Hendrik 
Published: November 2022

Abstract
The polysaccharide β-mannan, which is common in terrestrial plants but unknown in microalgae, was recently detected during diatom blooms. We identified a β-mannan polysaccharide utilization locus (PUL) in the genome of the marine flavobacterium Muricauda sp. MAR_2010_75. Proteomics showed β-mannan induced translation of 22 proteins encoded within the PUL. Biochemical and structural analyses deduced the enzymatic cascade for β-mannan utilization. A conserved GH26 β-mannanase with endo-activity depolymerized the β-mannan. Consistent with the biochemistry, X-ray crystallography showed the typical TIM-barrel fold of related enzymes found in terrestrial β-mannan degraders. Structural and biochemical analyses of a second GH26 allowed the prediction of an exo-activity on shorter manno-gluco oligosaccharides. Further analysis demonstrated exo-α-1,6-galactosidase- and endo-β-1,4-glucanase activity of the PUL-encoded GH27 and GH5_26, respectively, indicating the target substrate is a galactoglucomannan. Epitope deletion assays with mannanases as analytic tools indicate the presence of β-mannan in the diatoms Coscinodiscus wailesii and Chaetoceros affinis. Mannanases from the PUL were active on diatom β-mannan and polysaccharide extracts sampled during a microalgal bloom at the North Sea. Together these results demonstrate that marine microorganisms use a conserved enzymatic cascade to degrade β-mannans of marine and terrestrial origin and that this metabolic pathway plays a role in marine carbon cycling.
The genetic aetiology of cannabis use: from twin models to genome-wide association studies and beyond
Authors: Verweij Karin J. H. , Vink Jacqueline M. , Abdellaoui Abdel , Gillespie Nathan A. , Derks Eske M. , Treur Jorien L. 
Published: November 2022

AbstractCannabis is among the most widely consumed psychoactive substances worldwide. Individual differences in cannabis use phenotypes can partly be explained by genetic differences. Technical and methodological advances have increased our understanding of the genetic aetiology of cannabis use. This narrative review discusses the genetic literature on cannabis use, covering twin, linkage, and candidate-gene studies, and the more recent genome-wide association studies (GWASs), as well as the interplay between genetic and environmental factors. Not only do we focus on the insights that these methods have provided on the genetic aetiology of cannabis use, but also on how they have helped to clarify the relationship between cannabis use and co-occurring traits, such as the use of other substances and mental health disorders. Twin studies have shown that cannabis use is moderately heritable, with higher heritability estimates for more severe phases of use. Linkage and candidate-gene studies have been largely unsuccessful, while GWASs so far only explain a small portion of the heritability. Dozens of genetic variants predictive of cannabis use have been identified, located in genes such asCADM2,FOXP2, andCHRNA2. Studies that applied multivariate methods (twin models, genetic correlation analysis, polygenic score analysis, genomic structural equation modelling, Mendelian randomisation) indicate that there is considerable genetic overlap between cannabis use and other traits (especially other substances and externalising disorders) and some evidence for causal relationships (most convincingly for schizophrenia). We end our review by discussing implications of these findings and suggestions for future work.