bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neovascular Glaucoma Secondary to Bloch-Sulzberger Syndrome Documented by Retinography and Wide Field Angiography
Authors: Miguel Thiago Sande , Miguel Vinicius Sande , Miguel Bruna Sande , Neiva Rafaela Pereira , Costa Daniel Almeida da , Pereira Maurício Bastos 
Published: August 2022

Aims: To describe a Neovascular Glaucoma Secondary to Bloch-Sulzberger Syndrome.
Presentation of Case: A.B.F. female, 23 years old, claimed significant pain sensation and hyperemia in the left eye (LE) for 45 days, without triggering factors. She came to the consultation with a previous diagnosis of Bloch-Sulzberger Syndrome with pigmented lesions in the lower limbs since childhood, being followed up by dermatology since then.
Discussion: The diagnosis of IP (Incontinentia Pigmenti) is complex because it mimics other dermatoses. The impairment in other systems, such as the ophthalmic system, with the possibility of loss of vision and functional disability is a reality. The natural history of retinal lesions is not fully understood. Vascular changes seem to start in the first weeks of life and progress after birth for weeks or months, and may stabilize at any stage, leaving numerous sequelae.
Conclusions: Incontinentia pigmenti is difficult to diagnose and, at each evolutionary stage, presents many differential diagnoses. Eye injuries can lead to blindness as a consequence of ischemic events that can start soon after birth.
The impact of COVID‐19 workflow changes on radiation oncology incident reporting
Authors: Volpini Matthew E. , Lekx‐Toniolo Katie , Mahon Robert , Buckley Lesley 
Published: August 2022

AbstractBackgroundThe Ottawa Hospital's Radiation Oncology program maintains the Incident Learning System (ILS)—a quality assurance program that consists of report submissions of errors and near misses arising from all major domains of radiation. In March 2020, the department adopted workflow changes to optimize patient and provider safety during the COVID‐19 pandemic.PurposeIn this study, we analyzed the number and type of ILS submissions pre‐ and postpandemic precautions to assess the impact of COVID‐19‐related workflow changes.MethodsILS data was collected over six one‐year time periods between March 2016 and March 2021. For all time periods, the number of ILS submissions were counted. Each ILS submission was analyzed for the specific treatment domain from which it arose and its root cause, explaining the impetus for the error or near miss.ResultsSince the onset of COVID‐19‐related workflow changes, the total number of ILS submissions have reduced by approximately 25%. Similarly, there were 30% fewer ILS submissions per number of treatment courses compared to prepandemic data. There was also an increase in the proportion of “treatment planning” ILS submissions and a 50% reduction in the proportion of “decision to treat” ILS submissions compared to previous years. Root cause analysis revealed there were more incidents attributable to “poor, incomplete, or unclear documentation” during the pandemic year.ConclusionsCOVID‐19 workflow changes were associated with fewer ILS submissions, but a relative increase in submissions stemming from poor documentation and communication. It is imperative to analyze ILS submission data, particularly in a changing work environment, as it highlights the potential and realized mistakes that impact patient and staff safety.
Seroprevalence of anti‐myelin oligodendrocyte glycoprotein antibodies in adults with myelitis
Authors: Kim Ki Hoon , Kim Su‐Hyun , Hyun Jae‐Won , Kim Yeseul , Park Hyewon , Kim Ho Jin 
Published: August 2022

AbstractAlthough myelitis is the second most common presentation in adults with myelin oligodendrocyte glycoprotein (MOG) antibody‐associated disease (MOGAD), studies on MOG‐IgG seroprevalence in patients with myelitis episodes are sparse. Herein, we investigated MOG‐IgG seroprevalence in Korean adults who exhibited myelitis since 2017. Among 151 adults with acute myelitis, 11 (7.3%) tested positive for MOG‐IgG by the initial screening and 10 (6.6%) patients were finally diagnosed with MOGAD during the study period. This study is the first to provide data on MOG‐IgG seroprevalence in adults with myelitis and supports the clinical utility and importance of MOG‐IgG testing in myelitis episodes.
Elevation of Domain Wall Velocity Driven by Current Pulses in 2D Ferromagnetic Material Fe3GeTe2
Authors: Yang Chendi , Pei Ke , Yuan Mingyue , Qin Gang , Zhang Ruixuan , Wang Longyuan , Yang Liting , Che Renchao 
Published: August 2022

AbstractControlling the domain wall motion in the 2D ferromagnetic materials is significantly critical to the topological spin electronics, non‐volatile magnetic memories, and logic devices. The elevation of the domain wall velocity has become an urgent challenge. Herein, a current‐pulse‐driving strategy is unprecedentedly established to boost the domain wall velocity with an out‐of‐plane magnetic field and a rising temperature in the Fe3GeTe2 by using the in situ Lorentz Transmission Electron Microscopy. Elevation of domain wall velocity depends on the demagnetization energy increase and Zeeman energy reduction, which originates from the magnetic moments tilting by a non‐parallel to the magnetic field. By injecting ≈2000 times of alternative current pulses, a uniform instead of an unsynchronized domain wall velocity is achieved. The key mechanism lies in the decrease of the domain wall number, leading to a reduction in the expansion and compression of the domain areas. Optimized pulse parameters are applied with a critical duration of 60 ns and the density of ≈2 × 1010 A m−2, leading to an elevation of velocity from 0.0308 to 0.39 m s−1. The elevation in magnetic domain wall velocity can be useful for the application of 2D van der Waals ferromagnetic materials in future spintronic devices.
Dense Heterointerfaces and Unsaturated Coordination Synergistically Accelerate Electrocatalysis in Pt/Pt5P2Porous Nanocages
Authors: Li Yinghao , Kidkhunthod Pinit , Zhou Yingtang , Wang Xin , Lee Jong‐Min 
Published: August 2022

AbstractDesigning cost‐effective and durable Pt‐based catalysts is vital and challenging for practicable energy storage and conversion technologies. Here, a fast phosphating strategy to establish a Pt/Pt5P2porous nanocage with numerous heterointerfaces and defects is presented. It exhibits extraordinary activity and stability for both hydrogen evolution reaction (HER) with a small overpotential of 29 mV at 10 mA cm−2and methanol oxidation reaction (MOR) with a high mass activity of 1.37 A mg−1Ptat peak values, surpassing Pt/C. Microstructural analyzes show that many stacking faults are induced around heterointerfaces, while rich vacancies and atomic steps are created by the phosphorus‐induced thermal migration of Pt atoms, serving as highly active low‐coordination sites. X‐ray absorption spectroscopy and theoretical calculations reveal that introducing P atoms can modify the electronic configuration of Pt, thus optimizing H2O/H* binding strength and lowering water dissociation energy to accelerate HER, while decreasing the energy barrier of the rate‐limiting step (*CHO to *HCOOH) to facilitate MOR.
Air Induced Formation of Cs3Bi2Br9/Cs3BiBr6 Bulk Heterojunction and Its Dual‐band Photodetection Abilities for Light Communication
Authors: Cao Fa , Li Ziqing , Liu Xinya , Shi Zhifeng , Fang Xiaosheng 
Published: August 2022

AbstractMetal‐halide perovskites have long carrier diffusion lengths, low trap densities, and high carrier mobilities, and are therefore of value in the development of photodetectors (PDs). However, the research on dual‐band lead‐free perovskite bulk heterojunction has not been well developed. Here, a novel air induced formation of Cs3Bi2Br9/Cs3BiBr6 bulk heterojunction, reaching a high‐performance dual‐band photodetecting performance with an ultra‐violet main band (360 nm) peak responsivity of 5.6 mA W−1 and a blue sub‐band (450 nm) peak responsivity of 0.6 mA W−1 at 2 V, is reported. The bulk heterojunction exhibits superior photodetecting performance than that of lateral heterojunction. Furthermore, the PD exhibits a fast response speed (rise time 1.4 µs and decay time 2.0 µs) and good cyclic stability. Theoretical and experimental characterizations suggest Cs3Bi2Br9 exhibits a more stable structure in air than that of Cs3BiBr6. The dual‐band photodetection abilities of Cs3Bi2Br9/Cs3BiBr6 bulk‐heterojunction demonstrate great application prospects in light communication. These state‐of‐the‐art findings shed light on the fabrication of novel dual‐band high‐performance PDs based on lead‐free perovskite bulk‐heterojunction.
Semi‐Crystalline Rubber as a Light‐Responsive, Programmable, Resilient Robotic Material
Authors: Yang Qi , Shahsavan Hamed , Deng Zixuan , Guo Hongshuang , Zhang Hang , Liu Heng , Zhang Chunyu , Priimagi Arri , Zhang Xuequan , Zeng Hao 
Published: August 2022

AbstractPolymers with large and reversible light‐induced deformation offer a plethora of opportunities for the wireless control of small‐scale soft robots. However, their widespread adoption in real‐world applications is hindered, mainly due to their intrinsic softening upon illumination. Such limitation has detrimental effects on the achievable stress, durability, and precise positional control of the soft actuators after multiple cycles of use. Here, a synthetic rubber from a polybutadiene‐polyethylene copolymer is reported as a durable material for light‐controlled soft robots. The rubber can be programmed to exhibit various deformation modes controlled by visible‐to‐infrared light through a photothermal effect. Semi‐crystallinity of polyethylene within the rubbery network provides this material with a remarkable modulus at high temperatures (2.5 MPa at 100–140 °C), deformation repeatability (>90%) and shape‐recovery (>98%) after 100 actuation cycles subject to loads ranging from 10 to 10 000 times of its body weight (1.4 kPa–1.4 MPa). Soft robotic applications are demonstrated, such as thermally‐driven jumping and photo‐driven cargo transport carrying up to 1200 times its own weight. The results expand the portfolio of materials in designing remotely‐controlled, robust, and resilient soft robots working at small scales.
A Bioactive and Photoresponsive Platform for Wireless Electrical Stimulation to Promote Neurogenesis
Authors: Wu Chengheng , Pu Yiyao , Zhang Yusheng , Liu Xiaoyin , Qiao Zi , Xin Nini , Zhou Ting , Chen Suping , Zeng Mingze , Tang Jiajia , Pi Jinkui , Wei Dan , Sun Jing , Luo Fang , Fan Hongsong 
Published: August 2022

AbstractDelivering electrical signals to neural cells and tissue has attracted increasing attention in the treatment of nerve injuries. Unlike traditional wired electrical stimulation, wireless and remote light stimulation provides less invasive and longer‐lasting interfaces, holding great promise in the treatment of nerve injuries and neurodegenerative diseases, as well as human–computer interaction. Additionally, a bioactive matrix that bridges the injured gap and induces nerve regeneration is essential for injured nerve repair. However, it is still challenging to construct a 3D biomimetic cell niche with optoelectrical responsiveness. Herein, a bioactive platform for remote and wireless optoelectrical stimulation is established by incorporating hydrophilic poly(3‐hexylthiophene) nanoparticles (P3HT NPs) into a biomimetic hydrogel matrix. Moreover, the hydrogel matrix is modified by varying the composition and/or the crosslinking degree to meet the needs of different application scenarios. When exposed to pulsed green light, P3HT NPs in hydrogels convert light signals into electrical signals, resulting in the generation of tens of picoampere photocurrent, which is proved to promote the growth of cortical neurons that covered by hydrogels and the neuronal differentiation of bone marrow mesenchymal stem cells (BMSCs) encapsulated in hydrogels. This work is of great significance for the design of next‐generation neural electrodes and scaffolds.
Long‐Term Synergistic Antibacterial Composite Films Boosted by Controlled Underwater Surface Reconstruction
Authors: Wu Xinlei , Zheng Sijia , Yao Jun , Cao Zhihai 
Published: August 2022

AbstractImplanting bactericidal ability to low surface energy fluoropolymer is expected to develop advanced surfaces with excellent antibacterial performance for various applications. However, the fundamental conflicts, the difficulty of discharging release‐active bactericides from hydrophobic fluoropolymers and the trade‐off between the electrostatic contact‐active microbicides and the minimized surface interaction for contaminant release, are general consensus in the field and explain the very limited success in existing reports. The current work highlights an effective and feasible strategy that utilizes the interaction between silver nanoparticles (Ag NPs) and polymer matrices to generate composite films with controllable underwater surface reconstruction, enabling to regulate surface energy exquisitely to area facilitating the bacterial release and establish a synergistic bacteria‐killing action, and thereby boosting the bacteria‐killing and bacteria‐release simultaneously. Quaternized fluoropolymer/Ag NPs nanocomposite particles (qf‐polymer/Ag NCPs) are first synthesized through miniemulsion polymerization, and then used as building blocks to fabricate the quaternized fluoropolymer/Ag NPs nanocomposite films (qf‐polymer/Ag CFs) through a convenient squeegeeing technique. The qf‐polymer/Ag CFs display long‐term antibacterial performance against diverse bacteria. A synergistic antibacterial mechanism contributed by the Ag NPs, quaternary ammonium, and fluorinated components is proposed. This work provides new insight into the design, fabrication, and performance optimization of long‐term antibacterial surfaces for diverse applications.
Self‐Alignment Embedded Thin‐Film Transistor with High Transparency and Optimized Performance
Authors: Zheng Fei , Li Lei , Hu Luodan , Huang Xiaoqing , Kuo Tze‐Peng , Chang Kuan‐Chang 
Published: August 2022

AbstractAmorphous oxide semiconductor thin‐film transistors (AOS TFTs) have shown significant potential in the applications of increasingly advanced transparent and flexible electronic devices, where high speed, high transparency, and low power consumption are highly demanded. Yet, typical back‐channel etch (BCE) configuration used in the majority of TFTs still suffers from poor gate controllability, severe electrical field dispersion, relatively large parasitic capacitance and contact resistance. Here, a new embedded structure for TFTs with self‐alignment and even simpler fabrication process, outperforming conventional BCE counterpart in above aspects, is proposed in this work. More concentrated electrical field, improved gate control ability accompanied with lower contact resistance are achieved in the embedded TFTs. Consequently, superior electrical characteristics with subthreshold swing of 106.7 mV dec−1 and mobility as high as 32.10 cm2 V−1 s−1 are obtained. In addition, leakage current as well as contact resistance evidently decline compared to that in traditional BCE TFTs. By the assistance of Silvaco TCAD simulation, the performance and mechanism behind are cross‐validated from another perspective. Overall, such embedded configuration has equipped TFTs with appealing performance and it is also possible to enable other devices exploiting such structure with new possibility and thus a broader application.
Coherent Control of the Nonlinear Emission of Single Plasmonic Nanoantennas by Dual‐Beam Pumping
Authors: Di Francescantonio Agostino , Locatelli Andrea , Wu Xiaofei , Zilli Attilio , Feichtner Thorsten , Biagioni Paolo , Duò Lamberto , Rocco Davide , De Angelis Costantino , Celebrano Michele , Hecht Bert , Finazzi Marco 
Published: August 2022

AbstractThe control of nonlinear optical signals in nanostructured systems is pivotal to develop functional devices suitable for integration in optical platforms. A possible control mechanism is exploiting coherent interactions between different nonlinear optical processes. Here, this concept is implemented by taking advantage of the strong field enhancement and high optical nonlinearity provided by plasmonic nanostructures. Two beams, one at the angular frequency ω, corresponding to the telecom wavelength λ = 1551 nm, and the other at 2ω, are combined to generate a sum‐frequency signal at 3ω from single asymmetric gold nanoantennas. This nonlinear signal interferes with the third‐harmonic radiation generated by the beam at ω, resulting in a modulation up to 50% of the total signal at 3ω depending on the relative phase between the beams. Such a large intensity modulation of the nonlinear signal is accompanied by a rotation of its polarization axis, due to the lack of central symmetry of the nanostructure. The demonstration that the nonlinear emission can be coherently controlled through the phase difference of the two‐color illumination represents a promising route toward all‐optical logic operations at the nanoscale through nonlinear optical signal manipulation.
All‐Inorganic Functional Phosphor–Glass Composites by Light Curing Induced 3D Printing for Next‐Generation Modular Lighting Devices
Authors: Yang Jiaxin , Feng Ming , Zhang Kang , Chen Ziyu , Xu Rui , Khan Adnan , Li Yan , Xie Jinyue , Liu Lisa , Song Feng , Huang Wei 
Published: August 2022

AbstractDigital light processing 3D printing and pressureless sintering are combined to construct color‐tunable all‐inorganic functional composites by a simple and general strategy. The insertion of Y3Al5O12:Ce (YAG:Ce) into silica glass (YAG:Ce‐PiSG) is realized by pressureless sintering based on silica nanocomposites for 3D printing, which effectively controls the intense interface reaction between phosphor and substrate. The chromaticity of YAG:Ce‐PiSG‐based white light‐emitting diodes (WLEDs) shifts from blue‐white to white and yellow, and the 3D‐printed dome structure aids in the heat dissipation and pump blue light utilization. In addition, a series of red‐emitting color converters (CASN:Eu‐PiBSG) are synthesized by cofiring CaAlSiN3:Eu (CASN:Eu) with low softening‐point borosilicate glass powders, overcoming the fatal drawback of inherently low thermal performance. The chromaticity of integrated YAG:Ce‐PiSG/CASN:Eu‐PiBSG‐based WLEDs benefiting from 3D printing technology is adjusted in the color range from cold white to warm white. A warm WLED with high luminous efficiency (92.6 lm W−1) and excellent color rendering index (90.2) is successfully assembled. The 3D printed customizable phosphor–glass composites offer a great potential to develop high‐power and color‐tunable WLEDs, which are also of great significance for developing innovative glass composites with high‐temperature stability.
Phosphine‐Catalyzed (4+2) Annulation of Alkenes with Acidic Hydrogen‐Tethered Allylic Carbonates
Authors: Liao Jianning , Han Qihuan , Liu Min , Shi Wangyu , Xu Jiaqing , Wang Wei , Wu Yongjun , Guo Hongchao 
Published: August 2022

AbstractPhosphine‐catalyzed (4+2) annulation of the acidic hydrogen‐tethered allylic carbonates with electron‐deficient alkenes was achieved. Various electron‐deficient alkenes and allylic carbonates were well tolerated under mild reaction conditions, providing a variety of polysubstituted spirocyclohexenes, spirocyclohexanones or cyclohexanones in moderate to high yields. The scale‐up reactions and further transformations of the products had been performed. The acidic hydrogen‐tethered allylic carbonates displayed nice reactivity and will find more applications.magnified image
Prader–Willi syndrome, deletion subtypes, and magnesium: Potential impact on clinical findings
Authors: Butler Merlin G. , Cowen Neil , Bhatnagar Anish 
Published: August 2022

AbstractPrader–Willi syndrome is a complex neurodevelopmental genetic imprinting disorder with severe congenital hypotonia, failure to thrive with learning and behavioral problems, and hyperphagia with obesity developing in early childhood. Those with the typical 15q11–q13 Type I deletion compared with the smaller Type II deletion have more severe neurobehavioral problems and differ by the absence of four genes in the 15q11.2 BP1–BP2 region. Two of the genes encode magnesium transporters supporting brain and neurological function and we report on magnesium levels in the two deletion groups of PWS participants. We measured baseline plasma magnesium and analyzed data from a PWS cohort with and without the Type I or Type II deletion. Significantly lower plasma magnesium levels were found in PWS participants with the larger Type I deletion and more so with females with Type I deletion compared with females having the Type II deletion, although magnesium levels remained within normal range in both subgroups. Those with PWS and the larger 15q11–q13 Type I deletion were more clinically affected than those with the smaller Type II deletion. Two of the four genes missing in those with the larger deletion code for magnesium transporters and may impact magnesium levels. Our study showed lower magnesium levels in those with the larger deletion which could contribute to neurobehavioral differences seen in the two separate 15q11‐q13 deletion subtypes and in addition affect both glucose and insulin metabolism impacting comorbidities but will require more research.
Recent Developments in Nucleophilic Fluorination with Potassium Fluoride (KF): A Review
Authors: Khandelwal Manisha , Pemawat Gangotri , Kanwar Khangarot Rama 
Published: August 2022

AbstractFluorinated compounds act as a link between synthetic organic chemistry and medicinal chemistry and compel researchers to explore modified and innovative methods for the syntheses of fluorinated motifs. The identification of reliable and efficient methods for the fluorination of organic moieties remains a major challenge in synthetic organic chemistry. Nucleophilic fluorination reactions using a combination of potassium fluoride (KF) and various catalysts or promoters emerged as a viable strategy and provided access to versatile organofluorine compounds. This review will emphasize recent advancements in nucleophilic fluorination reactions using KF: aliphatic nucleophilic fluorination, aromatic nucleophilic fluorination, and heteroatomic nucleophilic fluorination with ionic liquids, modified crown ethers, and transition metal‐catalysts in various protic and aprotic media.