bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multimorbidity Among Migrant and Non-Migrant Ghanaians: The RODAM Study
Authors: Marzà-Florensa Anna , Boateng Daniel , Agyemang Charles , Beune Erik , Meeks Karlijn A. C. , Bahendeka Silver , Levitt Naomi , Klipstein-Grobusch Kerstin 
Published: December 2021

Objectives: Multimorbidity is a growing public health concern due to the increasing burden of non-communicable diseases, yet information about multimorbidity in low- and middle-income countries and migrant populations is scarce. We aimed to investigate the distribution and patterns of multimorbidity in rural and urban areas in Ghana and Ghanaian migrants in Europe.Methods: The RODAM cross-sectional study included 4,833 participants. Multimorbidity was defined as presence of multiple non-communicable chronic conditions. Patterns were determined from frequent combination of conditions. Prevalence ratios were estimated by logistic regression.Results: Prevalence of multimorbidity was higher in women and in urban Ghana and Europe. We observed a cardiometabolic pattern in all sites as well as circulatory-musculoskeletal and metabolic-musculoskeletal combinations in Ghana. Multimorbidity prevalence ratios were higher in Europe (men 1.47, 95% CI 1.34–1.59, women 1.18, 1.10–1.26) and urban Ghana (men 1.46, 1.31–1.59, women 1.27, 1.19–1.34).Conclusion: Distribution and patterns of multimorbidity differed by sex and site. With a higher burden of multimorbidity in urban areas, prevention strategies should focus on forestalling its increase in rapidly growing rural areas.
Workplace Violence Among Health Care Professionals in Public and Private Health Facilities in Bangladesh
Authors: Shahjalal Md. , Gow Jeff , Alam Mohammad M. , Ahmed Tanvir , Chakma Samar K. , Mohsin Faroque M. , Hawlader Mohammad D. H. , Mahumud Rashidul A. 
Published: December 2021

Objectives: The main objectives of this study were to examine the prevalence of workplace violence (WPV), its associated factors and explore the experiences of healthcare workers.Methods: A hospital-based cross-sectional study design used a nationally representative sample of 1,081 healthcare workers covering eight administrative divisions of Bangladesh. Logistic regression analysis was employed to estimate the adjusted effect of independent factors on WPV among healthcare workers.Results: Of the participants, 43% (468) experienced some form of WPV. Of those, 84% reported experiencing nonphysical violence, and 16% experienced physical violence in the past year. About 65% of victims claimed no action was taken to investigate the incident, and 44% reported no consequence for perpetrators. Four factors: being married (AOR = 1.63; CI: 1.12–2.39); public sector healthcare worker (AOR = 2.74; CI:1.99–3.76); working in an emergency department (AOR = 2.30; CI:1.03–5.12); and undertaking shift work (AOR = 1.52; CI: 1.10–2.11) were found to be significantly associated with WPV. One-third of the participants were worried about violence in their workplace.Conclusion: WPV is highly prevalent among healthcare workers in Bangladesh. Formal guidelines for reporting and managing WPV are urgently needed at the individual, hospital, and national levels.
Embryo Culture, In Vitro Propagation, and Molecular Identification for Advanced Olive Breeding Programs
Authors: Montilon Vito , Susca Leonardo , Potere Oriana , Roseti Vincenzo , Campanale Antonia , Saponari Antonia , Montemurro Cinzia , Fanelli Valentina , Venerito Pasquale , Bottalico Giovanna 
Published: December 2021

The high biodiversity of the olive tree is an important opportunity to develop sustainable plans to control Xylella fastidiosa (Xf) through breeding programs. Olive tree breeding activities have been limited due to various features of this species including the long time required for seed germination caused by the inhibition effect of the woody endocarp, the seed integument, and the endosperm. Starting from F1 seeds by cross-breeding, the embryo culture was compared with traditional seed germination, evaluating the effectiveness of in vitro multiplication of the plantlets for large-scale production. The isolated embryos were established on a new medium based on Rugini ‘84 macroelements, Murashige & Skoog ‘62 microelements, with Nitsch J. P. & Nitsch C. ‘69 vitamine and subcultured on Leva MSM modified. The results obtained confirmed that in vitro culture of olive embryos is a valid tool for increasing the percentage and speed of germination, helping to reduce the time of the olive breeding programs, offering the possibility to effectively propagate plantlets for further experiments.
Peptidoglycan-Free Bacterial Ghosts Confer Enhanced Protection against Yersinia pestis Infection
Authors: Dentovskaya Svetlana V. , Vagaiskaya Anastasia S. , Platonov Mikhail E. , Trunyakova Alexandra S. , Kotov Sergei A. , Krasil’nikova Ekaterina A. , Titareva Galina M. , Mazurina Elizaveta M. , Gapel’chenkova Tat’yana V. , Shaikhutdinova Rima Z. , Ivanov Sergei A. , Kombarova Tat’yana I. , Gerasimov Vladimir N. , Uversky Vladimir N. , Anisimov Andrey P. 
Published: December 2021

To develop a modern plague vaccine, we used hypo-endotoxic Yersinia pestis bacterial ghosts (BGs) with combinations of genes encoding the bacteriophage ɸX174 lysis-mediating protein E and/or holin-endolysin systems from λ or L-413C phages. Expression of the protein E gene resulted in the BGs that retained the shape of the original bacterium. Co-expression of this gene with genes coding for holin-endolysin system of the phage L-413C caused formation of structures resembling collapsed sacs. Such structures, which have lost their rigidity, were also formed as a result of the expression of only the L-413C holin-endolysin genes. A similar holin-endolysin system from phage λ containing mutated holin gene S and intact genes R-Rz coding for the endolysins caused generation of mixtures of BGs that had (i) practically preserved and (ii) completely lost their original rigidity. The addition of protein E to the work of this system shifted the equilibrium in the mixture towards the collapsed sacs. The collapse of the structure of BGs can be explained by endolysis of peptidoglycan sacculi. Immunizations of laboratory animals with the variants of BGs followed by infection with a wild-type Y. pestis strain showed that bacterial envelopes protected only cavies. BGs with maximally hydrolyzed peptidoglycan had a greater protectivity compared to BGs with a preserved peptidoglycan skeleton.
FORMATION OF ENVIRONMENTAL COMPETENCY OF STUDENTS OF BIOLOGICAL SPECIALTIES IN THE PROCESS OF POLISH PRACTICE
Authors: GOMLYA L. 
Published: December 2021

Organizational-process possibilities of the educational field practice for the purpose of ecological competence forming for the students of biological specialties have been presented in the article. Basic factors which complicate students ecological competence forming, fundamental directions of its formation in the process of organization and realization field practice have been underlined in the article.The content of field practice requires additional information on the methods of environmental monitoring in the environment and on the domestic issues. Particularly relevant is the saturation of field practices with the tasks of applied local history and those that affect the spheres of domestic activities and human impact on the environment. Methods of educational impact on students are also needed. Among the generally positive conditions for the formation of environmental competence of students (the presence of ecological content in the discipline, the possibility of self-realization during seminars and laboratory classes, the practical application of acquired knowledge in field practice), there are factors that impede the formation of this quality. Among them is the lack of content of the environmental issues of the local rank and the practical absence of information relating to the domestic sphere of the person's activities (complicates the decision-making process and responsibility for the state of the surrounding environment), the prevailing use of educational and educational methods that contradict the norms of environmental behavior (make it impossible to form a value the attitude towards nature, environmental motivation and related activities, suppress the readiness to preserve nature and the responsibility for it with en).
IMPLEMENTATION OF THE CDIO APPROACH TO ENGINEERING EDUCATION IN THE SYSTEM OF TRAINING FUTURE ECONOMISTS AND MANAGERS
Authors: DUTKA G. , LUTSENKO G. 
Published: December 2021

Conceptual frameworks and principles of CDIO approach in the context of modernization of engineering education are considered. The correspondence between CDIO approaches to the description of learning outcomes and competency-based approach is analyzed. The direction of the implementation of CDIO approach for other specialties is specified. The possibilities of design of interdisciplinary educational programmes are considered. Approaches of the using of CDIO in economics and management education are considered.By studying the research of foreign authors, we have found several attempts to adapt the CDIO approach to the needs of economic education. The common motive for such activities, which researchers emphasize, is to enhance the relevance of economic education in the context of further professional activities and to improve the quality of vocational training through the development of design skills and general competencies related, inter alia, to project management, work in multidisciplinary teams, communication and collaboration . The difficulties encountered by the researchers include the low level of knowledge of teachers and the management of OHS about the possibilities of the CDIO approach, which complicates the implementation process. Overcoming this is possible through the organization of joint projects for students of different specialties, trainings and internships for teachers of non-engineering specialties.
PHARMACOECONOMIC ANALYSIS AS AN INSTRUMENTATION FOR THE RATIONALE OF PHARMACOTHERAPY AND EVALUATION OF PHARMACY IN PROFESSIONAL PREPARATION OF FUTURE PHARMACISTS IN HIGHER EDUCATIONAL INSTITUTIONS
Authors: KONOVALOVA L. 
Published: December 2021

The article deals with the pharmacoeconomic analysis as a tool for substantiating rational pharmacotherapy and evidence-based pharmacy in the process of professional training of prospective pharmacists to solve the scientific and practical problem of improving the training of pharmacoeconomics of future pharmacists in higher education institutions, designing and developing a methodology for training pharmacoeconomics of future pharmacists for solving social problems regarding requests of qualified modern pharmaceutical personnel and their qualitative training in the system of higher education. In order to improve the pedagogical process, a methodology for training pharmacoeconomics of future pharmacists in higher educational institutions has been developed. The experimental research of implementation of the methodology of pharmacoeconomics training in the process of preparation of future pharmacists in higher medical educational institutions has been carried out, pedagogical experiment has been carried out. According to the results of an experimental study during the formation experiment positive dynamics of student achievements was established.
IMPLEMENTATION OF HEALTH-SAFETY TECHNOLOGIES IN EDUCATION UNITS
Authors: ONIPKO V. , DIACHENKO-BOHUN M. 
Published: December 2021

The basic concept for the preparation of future teachers of natural sciences to implement technology maintaining health in the educational process in secondary schools. The analysis of certain terms describing the specified educational process. Found that define the content and nature of the basic concepts is an important aspect of the process of preparing future teachers of natural sciences at higher education institutions to preserve the health of students. It is reported that one of the main objectives of the educational process is the active use of various technologies improving character. It is noted that competent implementation of technologies depends on maintaining health professional readiness of teachers for targeted prevention and rehabilitation of schoolchildren. It provides the necessary level of training of teachers in higher education institutions, consolidation of resources natural content of education, its development focus on maintaining health and improving the technological component of preparing students for practice.
ECONOMIC APPLIED TASKS AS A WAY TO ENLARGE MOTIVATION WHEN LEARNING ADVANCED MATHEMATICS IN TECHNICAL UNIVERSITY
Authors: RASSOKHA I. , BLAZHKO L. , HALAYDA T. 
Published: December 2021

The problems of students' motivation in studying advanced mathematics by students of economic specialties are considered. The ways of its increase are shown by the use of applied tasks related to the problems of the region.The authors analyzed the research motives, which encourage students of the first year to study, based on the problem of increasing motivation. One of the ways of its solution suggested by the authors is the application of applied tasks at studying of advanced mathematics. Among several classes of applied tasks, the application of applied tasks that are directly related to the future professional activity of students are considered and based on statistical data taken from specific enterprises of the region. The authors identified the main stages of solving such tasks and designated the main difficulties that may arise. For example, mathematical solution of an economic task can be given in the form of the following steps: the construction of a mathematical model which would reflect those properties of the object that really affect the investigated indicator and are consistent with known standard mathematical schemes; the choice of a solution method or a research of a model that directly depends on the quality of the model; directly the process of solution, which is purely mathematical; economic interpretation of the obtained result. As one of the key stages the authors consider the construction of a mathematical model of this process. In the article the role of mathematical modeling for increasing students' motivation in the study of advanced mathematics is considered. Basing on many years of experience, the authors showed the application of applied tasks in the study of linear algebra by students of economic specialties in the Poltava region. Also there is highlighted a number of specific tasks that the teacher can solve, using the proposed approach in the classes. Namely: the consolidation of theoretical knowledge, the formation of skills for the application of theoretical knowledge in practice, the development of skills for analysis, synthesis, induction, deduction and model construction, increasing motivation to study. Thus, in order to increase the efficiency of the perception of theoretical material and to increase the motivation to study advanced mathematics, it is useful for students to use not only applied tasks related to the specialty on which students study, but also to fill them with specific statistical data taken from enterprises of a certain region.
HIGHER EDUCATION OF THE FIRST DECADE OF THE XX CENTURY ON THE TERENES OF MODERN UKRAINE: SPECIFICATION OF THE HISTORICAL AND PEDAGOGICAL DISCOURSE
Authors: TKACHENKO A. 
Published: December 2021

The article represents the results of the analysis of specific characteristics of the development of higher education in Ukraine during the first two decades of the 20th century as an object of historical and pedagogical searches. In the course of research, the content differences of such attributive characteristics of the evolution of high school of the specified time as polymorphism (extraordinary typological diversity), context (the whole set of systemic connections of the historical and pedagogical phenomenon), peculiarities of periodization (parallelism of the development of higher education in regions that are different its national-state affiliation, versatility and polycontextuality of historical events, heterochronous processes of social development), trends of development (increased I diversity of types and the total number of higher education; the growth of the mass of higher education and the access of women to it; the liberalization of higher education management, the complication of teaching systems, the content of teaching, methodological provision of disciplines in high school; an increase in the proportion of practice-oriented methods and forms of study in higher education institutions education, decolerization of the content of education by increasing the proportion of profile disciplines, the revival of the Ukrainian national component in the activities and content of higher education education).
INFORMATION SOCIETY AND THE STATE INFORMATION POLICY IN UKRAINE
Authors: TOPOLNYK Y. 
Published: December 2021

In the article considers aspects of the problem of the formation of the new information society. The systematization of the main approaches to the definition of “information society” is showed: technological, economic, professional, spatial (network), cultural, political. The notion of "information society" is defined as a global society shaped by the intensive development of information and communication technologies, in which the main condition for the well-being of each person and each state is the knowledge gained through unhindered access to information and the ability to work with it, and the exchange of information is not will have neither temporal, spatial and political boundaries. Information policy is implemented on two levels – the state (national) and international. Each national state establishes a national information policy independently, depending on its own socio-economic, political and cultural conditions. The main directions of the national information policy are indicated. The peculiarities of the construction of the state information policy in Ukraine are noted. The state contributes to the development of the information society by creating an acceptable legislative field for the development of information and communication technologies. First of all, it is the Constitution and laws of Ukraine, presidential decrees and government programs and decrees, regulations and orders of ministries and departments, decisions and programs of central and local governments. In the context of European integration of Ukraine, the problem of studying the information society formation experience in the member states of the European Union, as well as the implementation of the EU legal acts norms in the information legislation of Ukraine is actualized. The list of strategic development priorities of Ukraine includes the rights protection, freedoms and security of citizens in the information sphere, the refusal of total information control ideas and the economy innovative branches development, in particular the domestic industry of information technologies, services provision and production of software products.
INNOVATIVE METHODS OF TEACHING OF IN TECHNICAL
Authors: USOVA V. 
Published: December 2021

Institutes of higher In the article are analyses methods of studies in INSTITUTE of higher of technical direction. Main attention is accented on the innovative methods of teaching which effectively influence on forming of specialist of new type.The experience of work allows to state that every student can be successful if the final control on the discipline "Cognition" is carried out in a non-shaded form - an exam (a test) - an indication of the ancient Ukrainian rite, to which the student group prepares a national rite, using local material. Teachers set the task for the students to receive bright emotional impressions, broadened their knowledge of folk traditions. It is important that everyone can prove himself to be a narrator, a singer, an organizer, a hand-dealer, a journalist, a director, a photographer, etc. In order to popularize popular knowledge, it is worthwhile to write an article about a rite in a student's newspaper, make a video story. This approach to final control helps in an interesting, unobtrusive form to shape the outlook and character of the future specialist in the spirit of the Ukrainian national idea.
THE MANAGEMENT OF THE PROCESS OF INNOVATIVE CULTURE FORMATION OF FUTURE PRIMARY SCHOOL TEACHER: THE THEORETICAL ASPECTS
Authors: SHEVCHUK M. 
Published: December 2021

The article deals with the problem of the preparation of a primary school teacher as the founder of educational innovations, professionally prepared for a productive creative response to the challenges of a globalized world. The formation of the innovative culture of future primary school teachers of a comprehensive school is a precondition for improving the educational environment of junior pupils and promotes the development of their personality. The author believes that the effectiveness of the formation of an innovative culture of future teachers, who will work with pupils of junior school age, depends on the management. The article provides theoretical analysis of the definitions of “culture”,“innovation”, “management”. The result of the theoretical study of encyclopedic-linguistic interpretations and interpretations of the above-mentioned terms by various scholars is the definition of the concepts of “innovative culture of the teacher”, “the formation of the innovative culture of the primary school teacher”. The author shows that under the conditions of permanent changes of modern education, the controlled formation of the innovative culture of future primary school teachers serves a specially organized management process, which involves the achievement of positive changes in the managed object due to purposeful rational volitional actions. In this case, the role of managing the process of formation of the innovative culture of primary school future teachers in the conditions of educational transformations and new methods in the preparation of a competitive specialist in the field of education is increasing. The main conclusion of the article is the formulation of the definition, which reveals the essence of the concept of “management of the process of innovative culture formation of future primary school teacher”.