bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incremental equilibrium assignment and applications to traffic network model
Authors: Sun Chao , Jing Haodong , Chen Taolüe , Li Menghui , Zhang Peng 
Published: October 2022

AbstractTo find a traffic assignment algorithm that is less complex than the current algorithms in terms of both methodology and implementation, the route‐based incremental equilibrium assignment (IEA) method is proposed. The IEA method iteratively performs incremental assignment and new origin‐destination (O‐D) demand extraction, where the new O‐D demand is obtained by aggregating the traffic flows from the routes whose travel times are greater than the shortest travel time. By extending the IEA method, the incremental stochastic user equilibrium and reliability‐based user equilibrium assignments are proposed to solve the stochastic user equilibrium (SUE) and reliability‐based user equilibrium (RUE) models, respectively. The traffic flow assignment and new O‐D demand extraction are carried out in terms of the route choice probability and the ratio of route flow to O‐D demand in the incremental stochastic user equilibrium assignment method; the redundant traffic flows from the non‐equilibrium routes are extracted. Unlike the IEA method, incremental reliability‐based user equilibrium assignment needs to derive both the mean and variance of the route travel time. The results from numerical experiments demonstrate the essential ideas and convergence performance of the proposed IEA algorithm and illustrate that IEA can be effectively extended to solve the SUE and RUE models.
A photopaper‐based low‐cost, wideband wearable antenna for wireless body area network applications
Authors: Jabbar Abdul , Zubair Muhammad , Naveed Muhammad Ashar , Mehmood Muhammad Qasim , Massoud Yehia 
Published: October 2022

AbstractThis study presents a low‐cost, compact, flexible, and wideband wearable antenna for different wireless body area network (WBAN) band applications, covering medical body area network band of 2.4 GHz, industrial, scientific, and medical band of 2.45 GHz, WiMAX band of 3.5 GHz, and wireless local area network band of 5.2 GHz. The final antenna topology is obtained by hexagonal microstrip radiator patch fabricated on commercially available low‐cost photo paper substrate and defected ground plane below the feed line acting as a partial ground to achieve a conformable structure wideband operation. The overall size of the fabricated antenna is 30 × 40 mm2 and yields a wide‐bandwidth of 3 GHz (2.30–5.30 GHz), radiation efficiency of 84.35%, and the highest gain of 3.48 dBi at the centre frequency of 5.2 GHz, and minimum gain of 1.91 dBi at 2.45 GHz. Furthermore, our detailed numerical and experimental investigations involving specific absorption rate performance assessment and bending analysis revealed the proposed design's excellent robustness to both human body loading and structural deformation scenarios. Therefore, simulated and measured results strongly advocate that the proposed design has profound implications for flexible and body‐worn devices in WBAN applications.
An alternative method of dispersive solid‐phase extracting Hg (II) from environmental aqueous solutions using carboxylic functionalized carbon nanotubes
Authors: karimnezhad Kamelia , Moghimi Ali , Adnan Rohana , Abniki Milad 
Published: October 2022

AbstractThis study is a simple method for rapid sample preparation before instrumental experiment, which is an important tool and the main step in an analytical proceeding. Till now, different sample preparation procedures based on solid‐phase extraction manner were developed to isolate different types of analytes from different matrices. In this method, the preconcentration and removal of trace amounts of Hg (II) ion in aqueous samples with nanotubes functionalized carboxyl are displayed. The analysis of Hg2+ ions concentration in water solutions was accomplished by flame atomic absorption spectroscopy. Some parameters including the pH, value, and type of desorption eluent solvent, extraction time, ions effect etc. were optimized. The Freundlich, Langmuir, Temkin, and Dubinin–Radushkevich models were employed to estimate Hg (II) ions adsorption. The Freundlich model was obtained from the study of isotherm studies. The kinetic studies demonstrate the adsorption of Hg (II) ions by adsorbent fitted with the pseudo‐second‐order type and resulting from that chemisorption is the rate‐limiting process in the Hg (II) adsorption. The concentration parameter such as level of detection of proposed method, and relative standard deviation test were obtained as 20.83, 6 µg L−1, and 1.16%, respectively.
A task segmentation and computing offload algorithm for mobile edge computing
Authors: Shi Xingyan 
Published: October 2022

AbstractIn the existing mobile edge computing (MEC) environment, edge servers have limited computing power and cannot process data in real time. To solve this problem, this paper proposes a task segmentation and computing offloading algorithm for mobile edge computing (MEC). Firstly, the computing tasks of mobile terminals are segmented under the network framework of cloud‐side‐device collaboration, and a task offloading optimization model is designed to minimize the total delay of mobile devices. Secondly, the computing resource allocation parameters and action space parameters are discretized, and a computing offloading algorithm based on Deep Q Network (DQN) is proposed. The algorithm extracts feature from high‐dimensional data and uses deep neural network to estimate Q‐value of actions to maximize the summation of system delays. Finally, simulation experiments show that when the cloud computing capacity is 7 × 1011 central processing unit (CPU) cycle/s, the total delay of proposed algorithm is only 1.116 s, while the total delays of comparison algorithms are 1.251 s and 1.193 s, respectively. Therefore, compared with the comparison algorithm, the proposed algorithm can better reduce the total system delay.
Design of a fully integrated VHF CP‐PLL frequency synthesizer with an all‐digital defect‐oriented built‐in self‐test
Authors: Kommey Benjamin , Boateng Kwame Osei , Yankey Jephthah , Addo Ernest Ofosu , Agbemenu Andrew Selasi , Tchao Eric Tutu , Akowuah Bright Yeboah 
Published: October 2022

AbstractThis paper presents the design of an on‐chip charge pump phase‐locked loop (CP‐PLL) with a fully digital defect‐oriented built‐in self‐test (BIST) for very‐high frequency (VHF) applications. The frequency synthesizer has a 40–100 MHz tuning range and uses a ring voltage‐controlled oscillator for frequency synthesis. The PLL exhibits a phase noise of −132 dBc/Hz at 1 MHz and consumes 1.8 mW on a 3 V supply. The BIST implementation uses fewer external input or output, is capable of efficient fault diagnosis, and is compact, posing a low area overhead. The integrated circuit design was realized in the AMI 0.6μ complementary metal‐oxide‐semiconductor process.
Meanderings of a Curious Chemist
Authors: Zard Samir Z. 
Published: October 2022

AbstractThis account relates briefly the personal trajectory of the author and the thought processes that went into solving synthetic problems and developing new reactions more generally useful in organic synthesis.1	Preamble and Early Education2	In France with Sir Derek Barton3	Chemistry at Ecole Polytechnique and at the ICSN4	Final Remarks
Imaging of Drug-Related Pneumonitis in Oncology
Authors: Tseng Shu-Chi , Lee Ho Yun , Nishino Mizuki 
Published: October 2022

AbstractClinical applications of novel anticancer agents in the past few decades brought marked advances in cancer treatment, enabling remarkable efficacy and effectiveness; however, these novel agents are also associated with toxicities. Among various toxicities, drug-related pneumonitis is one of the major clinical challenges in the management of cancer patients. Imaging plays a key role in detection, diagnosis, and monitoring of drug-related pneumonitis during cancer treatment. In the current era of precision oncology, pneumonitis from molecular targeted therapy and immune-checkpoint inhibitors (ICI) has been recognized as an event of clinical significance. Additionally, further advances of therapeutic approaches in cancer have brought several emerging issues in diagnosis and monitoring of pneumonitis. This article will describe the computed tomography (CT) pattern-based approach for drug-related pneumonitis that has been utilized to describe the imaging manifestations of pneumonitis from novel cancer therapies. Then, we will discuss pneumonitis from representative agents of precision cancer therapy, including mammalian target of rapamycin inhibitors, epidermal growth factor receptor inhibitors, and ICI, focusing on the incidence, risk factors, and the spectrum of CT patterns. Finally, the article will address emerging challenges in the diagnosis and monitoring of pneumonitis, including pneumonitis from combination ICI and radiation therapy and from antibody conjugate therapy, as well as the overlapping imaging features of drug-related pneumonitis and coronavirus disease 2019 pneumonia. The review is designed to provide a practical overview of drug-related pneumonitis from cutting-edge cancer therapy with emphasis on the role of imaging.
Microshear Bond Strength of Bioactive Materials to Dentin and Resin Composite
Authors: Ahmed Basma , Hamama Hamdi H. , Mahmoud Salah Hasab 
Published: October 2022

Abstract
Objectives The aim of this study was to comparatively evaluate microshear bond strength (μSBS) of bioactive ionic resin composite and resin-modified glass ionomer liner (RMGI) to dentin and resin composite.
Materials and Methods The enamel of 11 posterior molar teeth was removed to expose dentin and then placed in acrylic blocks. Each specimen received three microcylindrical Tygon tubes filled with bioactive ionic resin composite (Activa Bioactive base/liner (Pulpdent, MA, USA)), RMGI (Riva light cure SDI LTD, Bayswater, Australia), and resin composite (Filtek Z350xt, MN, USA). Composite discs (n = 11) were fabricated from nanofilled resin composite (Filtek Z350xt) and then fixed in acrylic blocks. Each specimen received two microcylindrical Tygon tubes filled with Activa Bioactive base/liner and Riva RMGI. All specimens were mounted individually to universal testing machine for μSBS test. Failure modes were analyzed using stereomicroscope and scanning electron microscope.
Results Filtek Z350xt nanofilled resin composite showed the highest μSBS values. No statistical significant difference was found between Activa Bioactive and Riva RMGI (p > 0.05).
Conclusion Bioactive ionic resin composite liner exhibited similar bond strength as RMGI to dentin and resin composite.
Early Childhood Caries and Oral Health-Related Quality of Life: Evaluation of the Effectiveness of Single-Session Therapy Under General Anesthesia
Authors: Ludovichetti Francesco Saverio , Zuccon Andrea , Cantatore Donatella , Zambon Giulia , Girotto Luca , Lucchi Patrizia , Stellini Edoardo , Mazzoleni Sergio 
Published: October 2022

Abstract
Objective  The aim of this study is to evaluate whether the treatment of ECC, performed in a single-session dental treatment under general anesthesia, can affect the quality of life of pediatric patients. It was assessed whether risks and discomforts involved in SSGA are outweighed by its effectiveness and reliability in improving oral health-related quality of life.
Materials and Methods The quality of life that was assessed in this prospective study was oral health-related quality of life (OHRQL). Pediatric patients aged between 3 and 6 years with ECC undergoing dental treatment in SSGA were asked to fill in the Early Childhood Oral Health Impact Scale (ECOHIS) form both before and 1 month after the intervention. The data obtained were then statistically elaborated and analyzed to evaluate the actual significance of the differences found between the values before and after treatment and between the two sexes.
Results Mean ECOHIS score before treatment was 30.58, following a large decrease after treatment, with a mean score of 2.94. Most parameters show a significant improvement between pre- and post-SSGA treatments, mainly those related to oral–dental pain, daytime irritability, and impact on family environment. Average ECOHIS scores for males and females are 31.72 and 29.76 before treatment and 3.55 and 2.52 1 month after treatment, respectively, showing no statistically significant differences.
Conclusion The dental treatment of young children under SSGA is associated with considerable improvement in their OHRQL. It can be considered an effective and reliable way of managing cases that cannot be dealt with by alternative methods.
Oral Health Attitude with the Socioeconomic Conditions of Mothers with Growth Stunting Children
Authors: Putri Nadhira Aulia , Setiawan Asty Samiaty , Setiawan Arlette Suzy 
Published: October 2022

Abstract
Objective This study analyzes the relationship between socioeconomic conditions and the attitude of mothers in maintaining the dental health of stunting children.
Materials and Methods The research method uses correlational test with Spearman rank. The sampling technique used purposive sampling based on the inclusion criteria of mothers who had stunted children in Lengkong District, Bandung City.
Result Data analysis by the Spearman Rank resulted p-value of 0.019 (p < 0.05) which leads to a positive relationship between socioeconomic conditions an mother's attitude in maintaining the dental health of stunting children.
Conclusion From the results of the study, it can be concluded that there is a relationship between socioeconomic conditions and the attitude of mothers in maintaining the dental health of stunting children in Lengkong District, Bandung City.
The Outcome of Progressive Uterine Sarcoma with Potential Bone Involvement
Authors: Al-Ibraheem Akram , Abdlkadir Ahmed S. 
Published: October 2022

AbstractHigh-grade endometrial stromal sarcoma (HGESS) is a very rare kind of uterine tumor that accounts for less than 2% of all uterine cancers. The usual sites of metastasis are the abdomen and lung, while bone metastasis is very rare, with only a few cases reported till now. We present a case of HGESS with bone metastasis and review the literature.
The Prevalence, Location, and Dimensions Of Interthalamic Adhesions and Their Clinical Significance: Corpse Brain Analysis
Authors: Patra Apurba , Ravi Kumar Satish , Asghar Adil 
Published: October 2022

Abstract
Background Interthalamic adhesion (ITA) or massa intermedia is a midline rod-like neural structure interconnecting the medial surfaces of two thalami. Its absence is considered as a midline defect associated with schizophrenia spectrum disorder. The present study aimed to determine the prevalence, location, and dimensions of the ITA in South Asian brains.
Materials and Methods One hundred midsagittal sections of adult cadaveric brains were examined for the presence or absence of ITAs, their location about the lateral wall of the third ventricle, and their dimensions.
Results ITA was found in 86 sections. In two cases, it was double. There was no significant relationship between the incidence of ITAs and sex (p > 0.05). The ITA was most commonly located in the anterosuperior quadrant. The horizontal diameter was 4.61 ± 1.17 mm, and the vertical diameter was 3.10 ± 0.78 mm. In all cases, the horizontal diameter was longer than the vertical. The average area of the ITA was significantly larger in females (17.56 ± 5.26 mm2) than in males (13.62 ± 5.22 mm2) (p = 0.025).
Conclusion Presence of ITA is common in South Asian brains, with usual location in the anterosuperior quadrant of the lateral wall of the third ventricle. The cross-sectional area of the ITA was significantly larger in females than in males. No correlation was found between the surface area of the ITA and the length of the third ventricle.
Study of Association of Various Psychiatric Disorders in Brain Tumors
Authors: Sharma Achal , Das Anand Kumar , Jain Akhilesh , Purohit Devendra Kumar , Solanki Ram Kumar , Gupta Ajay 
Published: October 2022

Abstract
Background Brain tumors may be associated with high morbidity, and psychiatric symptoms may be an early manifestation. It is important to address mental symptoms as early as possible because they are prone to develop psychiatric comorbidities in future. If untreated, these situations may worsen and lead to burden upon caregivers.
Methods A total of 176 brain tumor patients between January 2021 and January 2022 constituted the sample size. All recently diagnosed cases of brain tumor with age equal to or more than 18 years who can comprehend and answer questionnaires were included. Patients with a long history of brain tumor or who had a history of a psychiatric illness other than presenting symptoms or any other serious medical illness were excluded.
Results Twenty-seven percent of brain tumor patients had psychiatric symptoms. Depressive symptoms were the most common, associated with 24% of patients, followed by anxiety disorders. Psychiatric disorders were more common in supratentorial compared to infratentorial tumors. Psychiatric symptoms seem to be associated more commonly with malignant tumors and peritumoral edema. Among malignant tumors, depressive symptoms tend to be related with high-grade glioma, and among benign tumors, they were more common in meningioma. No predilection to laterality and anatomical lobe involvement is reported.
Conclusion Screening of psychiatric disorders should be a routine in brain tumor patients. An integrated approach is required to treat brain tumor patients. Healthcare professionals should be more vigilant about the onset of psychiatric symptoms and the need of palliative care to improve the quality of life.
Case presentations of medication management for patients at risk for drug-associated acute kidney injury identified with a CDS system and a novel biomarker
Authors: Williams Victoria L , Groetzinger Lara M , Smithburger Pamela L , Imhoff Allison , Culley Colleen M , Murugan Raghavan , Kellum John A , Kane-Gill Sandra L 
Published: October 2022

AbstractPurposeTraditional methods used to evaluate changes in kidney function to identify acute kidney injury (AKI) have significant limitations. Damage biomarkers can identify patients at risk for AKI prior to changes in kidney function. While clinical trials have shown that biomarker-guided treatment can improve outcomes, whether these biomarkers can influence providers’ choice of treatment strategy for risk prediction, surveillance, or diagnostic evaluation in clinical practice is uncertain.SummaryThis case series describes 4 patients at an academic medical center whose care was informed by kidney biomarker utilization in conjunction with a clinical decision support system (CDSS). Though each patient’s clinical presentation was unique, kidney biomarkers were successfully employed as clinical tools in evaluating the risks and benefits of nephrotoxic medications.ConclusionThis case series demonstrates 4 scenarios in which a kidney injury biomarker used in conjunction with CDSS and consideration of the patients’ clinical presentation informed treatment strategies with the intent to prevent AKI.
Structural basis for the substrate specificity switching of lysoplasmalogen-specific phospholipase D fromThermocrispumsp. RD004668
Authors: Hamana Hiroaki , Yasutake Yoshiaki , Kato-Murayama Miyuki , Hosaka Toshiaki , Shirouzu Mikako , Sakasegawa Shin-ichi , Sugimori Daisuke , Murayama Kazutaka 
Published: October 2022

ABSTRACTLysoplasmalogen-specific phospholipase D (LyPls-PLD) hydrolyzes choline lysoplasmalogen to choline and 1-(1-alkenyl)-sn-glycero-3-phosphate. Mutation of F211 to leucine altered its substrate specificity from lysoplasmalogen to 1-O-hexadecyl-2-hydroxy-sn-glycero-3-phosphocholine (lysoPAF). Enzymes specific to lysoPAF have good potential for clinical application, and understanding the mechanism of their activity is important. The crystal structure of LyPls-PLD exhibited a TIM barrel fold assigned to glycerophosphocholine phosphodiesterase, a member of glycerophosphodiester phosphodiesterase. LyPls-PLD possesses a hydrophobic cleft for the binding of the aliphatic chain of the substrate. In the structure of the F211L mutant, Met232 and Tyr258 form a “small lid” structure that stabilizes the binding of the aliphatic chain of the substrate. In contrast, F211 may inhibit small lid formation in the wild-type structure. LysoPAF possesses a flexible aliphatic chain; therefore, a small lid is effective for stabilizing the substrate during catalytic reactions.
Image-domain DAS 3D VSP elastic transmission tomography
Authors: Oren Can , Shragge Jeffrey 
Published: October 2022

SUMMARY
Full-wavefield elastic imaging of active-source seismic data acquired by downhole receivers commonly offers higher-resolution subsurface images in the vicinity of a borehole compared to conventional surface seismic data sets, which can lack higher-frequency wavefield components due to longer travel paths and increased attenuation. An increasingly used approach for downhole acquisition is vertical seismic profiling (VSP), which has become more attractive when coupled with distributed acoustic sensing (DAS) using optical fibres installed in wells. The main difficulty for generating high-quality images with full-wavefield imaging tools for DAS VSP data, though, is the need for an accurate velocity model. To build plausible velocity models using active-source DAS VSP data, we adopt a 3-D image-domain elastic transmission tomography technique, originally developed for surface-recorded passive (microseismic) data, by exchanging the source and receiver positions (i.e. reciprocity) to mimic a passive-seismic surface monitoring scenario. The inversion approach exploits various images for each source constructed through time-reverse imaging (TRI) of downgoing P- and S-wave first-arrival waveforms. The TRI process uses the kinetic term of the (extended) PS energy imaging condition that exhibits sufficient sensitivity to velocity model errors. The method automatically updates the P- and S-wave velocity models to optimize image focusing via adjoint-state inversion. We illustrate the efficacy of the adopted elastic inversion technique using an active-source DAS 3-D VSP field data set acquired in the North Slope of Alaska. The numerical experiments demonstrate that the inverted elastic velocity models can be further used in full-wavefield acoustic/elastic imaging algorithms to obtain accurate subsurface images.