bluuebunny/crossref_metadata_2025_split huggingface dataset:
Possible molecular states of $$D^{(*)}D^{(*)}$$ and $$B^{(*)}B^{(*)}$$ within the Bethe–Salpeter framework
Authors: Ke Hong-Wei , Liu Xiao-Hai , Li Xue-Qian 
Published: February 2022

AbstractRecently the LHCb collaboration reported a new exotic state $$T^+_{cc}$$

T

cc

+

which possesses $$cc\bar{u}\bar{d}$$

c
c

u

¯

d

¯

flavor structure. Since its mass is very close to the threshold of $$D^0D^{*+}$$

D
0

D

∗
+

(or $$D^{*0}D^{+}$$

D

∗
0

D
+

) and its width is very narrow, it is inclined to conjecture that $$T^+_{cc}$$

T

cc

+

is a molecular state of $$D^0D^{*+}$$

D
0

D

∗
+

(or $$D^{*0}D^{+}$$

D

∗
0

D
+

). In this paper we study the possible molecular structures of $$D^{(*)}D^{(*)}$$

D

(

∗
)

D

(

∗
)

and $$B^{(*)}B^{(*)}$$

B

(

∗
)

B

(

∗
)

within the Bethe–Salpeter (B–S) framework. We employ one boson exchange model to stand the interaction kernels in the B–S equations. With reasonable input parameters we find the isospin eigenstate $$\frac{1}{\sqrt{2}}(D^0D^{*+}-D^{*0}D^{+})$$

1

2

(

D
0

D

∗
+

-

D

∗
0

D
+

)

($$J^P=1^+$$

J
P

=

1
+

) constitutes a solution, which supports the ansatz of $$T^+_{cc}$$

T

cc

+

being a molecular state of $$D^0D^{*+}$$

D
0

D

∗
+

(or $$D^{*0}D^{+}$$

D

∗
0

D
+

). With the same parameters we also find that the isospin-1 state $$\frac{1}{\sqrt{2}}(D^{*0}D^{*+}+D^{*0}D^{*+})$$

1

2

(

D

∗
0

D

∗
+

+

D

∗
0

D

∗
+

)

($$J^P=0^+$$

J
P

=

0
+

) can exist. Moreover, we also study the systems of $$B^{(*)}B^{(*)}$$

B

(

∗
)

B

(

∗
)

and their counterparts exist as possible molecular states. Consistency of theoretical computations based on such states with the data of the future experiments may consolidate the molecular structure of the exotic state $$T^+_{cc}$$

T

cc

+

.
Study of naturally occurring radionuclides in the ECHo set-up
Authors: Göggelmann A. , Jochum J. , Gastaldo L. , Mantegazzini F. , Barth A. , Hammann R. 
Published: February 2022

AbstractThe determination of the effective electron neutrino mass by analyzing the end point region of the $$^{163}$$

163

Ho electron capture (EC) spectrum relies on the precise description of the expected $$^{163}$$

163

Ho events and background events. In the ECHo experiment, arrays of metallic magnetic calorimeters, implanted with $$^{163}$$

163

Ho, are operated to measure the $$^{163}$$

163

Ho EC spectrum. In an energy range of 10 eV below $$Q_{\mathrm {EC}}$$

Q
EC

, the maximum available energy for the EC decay of about 2.8 keV, a $$^{163}$$

163

Ho event rate of the order of $$10^{-4}$$

10

-
4

day$$^{-1}$$

-
1

pixel$$^{-1}$$

-
1

is expected for an activity of 1 Bq of $$^{163}$$

163

Ho per pixel. This means, a control of the background level in the order of $$10^{-5}$$

10

-
5

day$$^{-1}$$

-
1

pixel$$^{-1}$$

-
1

is extremely important. We discuss the results of a Monte Carlo study based on simulations, which use the GEANT4 framework to understand the impact of natural radioactive isotopes close to the active detector volume in the case of the ECHo-1k set-up, which is used for the first phase of the ECHo experiment. For this, the ECHo-1k set-up was modeled in GEANT4 using the proper geometry and materials, including the information of screening measurements of some materials used in the ECHo-1k set-up and reasonable assumptions. Based on the simulation and on assumptions, we derive the expected background around $$Q_{\mathrm {EC}}$$

Q
EC

and give upper limits of tolerable concentrations of natural radionuclides in the set-up materials. In addition, we compare our results to background spectra acquired in detector pixels with and without implanted $$^{163}$$

163

Ho. We conclude that typical concentration of radioactive nuclides found in the used materials should not endanger the analysis of the endpoint region of the $$^{163}$$

163

Ho EC spectrum for an exposure time of half a year.
Establishment and Verification of Logistic Regression Model for Qualitative Diagnosis of Ovarian Cancer Based on MRI and Ultrasound Signs
Authors: Guo Xiao , Zhao Guangcai 
Published: February 2022

Objective. To explore the establishment and verification of logistic regression model for qualitative diagnosis of ovarian cancer based on MRI and ultrasonic signs. Method. 207 patients with ovarian tumors in our hospital from April 2018 to April 2021 were selected, of which 138 were used as the training group for model creation and 69 as the validation group for model evaluation. The differences of MRI and ultrasound signs in patients with ovarian cancer and benign ovarian tumor in the training group were analyzed. The risk factors were screened by multifactor unconditional logistic regression analysis, and the regression equation was established. The self-verification was carried out by subject working characteristics (ROC), and the external verification was carried out by K-fold cross verification. Result. There was no significant difference in age, body mass index, menstruation, dysmenorrhea, times of pregnancy, cumulative menstrual years, and marital status between the two groups (

P
>
0.05

). After logistic regression analysis, the diagnostic model of ovarian cancer was established:

logit

P

=
−
1.153
+

MRI

signs
:
morphology
×
1.459
+
boundary
×
1.549
+
reinforcement
×
1.492
+
tumor

components
×
1.553

+

ultrasonic

signs
:
morphology
×
1.594
+
mainly

real
×
1.417
+
separated

form
×
1.294
+
large

nipple
×
1.271
+
blood

supply
×
1.364

; self-verification: AUC of the model is 0.883, diagnostic sensitivity is 93.94%, and specificity is 80.95%; K-fold cross validation: the training accuracy was

0.904
±
0.009

and the prediction accuracy was

0.881
±
0.049

. Conclusion. Irregular shape, unclear boundary, obvious enhancement in MRI signs, cystic or solid tumor components and irregular shape, solid-dominated shape, thick septate shape, large nipple, and abundant blood supply in ultrasound signs are independent risk factors for ovarian cancer. After verification, the diagnostic model has good accuracy and stability, which provides basis for clinical decision-making.
Coronary Artery Bypass Grafting and Percutaneous Coronary Intervention in Patients With Chronic Total Occlusion and Multivessel Disease
Authors: Lin Shen , Guan Changdong , Wu Fan , Xie Lihua , Zou Tongqiang , Shi Yanpu , Chen Sipeng , He Li , Xu Bo , Zheng Zhe 
Published: February 2022

Background:
Percutaneous coronary intervention (PCI) has been used increasingly as an alternative means of revascularization for patients with chronic total occlusion and multivessel disease. We investigated 5-year clinical outcomes following coronary artery bypass grafting (CABG) and PCI in patients with chronic total occlusion and multivessel disease.

Methods:
In this single-center, retrospective cohort study, 4324 consecutive patients with ≥1 chronic total occlusion and multivessel disease were treated with either CABG (n=2264) or PCI (n=2060) between 2010 and 2013. The primary outcome was 5-year composite of death, myocardial infarction, or stroke. An inverse-probability-of-treatment weighting method was used adjusting for both patient and lesion characteristics.

Results:

The unadjusted 5-year composite outcomes were similar between CABG group and PCI group (12.1% [258/2264] versus 11.4% [218/2060];
P
=0.52). After adjustment for baseline variables, PCI was associated with significantly higher risk of composite outcomes (adjusted hazard ratio: 1.21 [95% CI, 1.02–1.44];
P
=0.03). The inferiority of PCI in 5-year composite outcome was significant in patients with CABG recommendation according to SYNTAX (Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery) score II (adjusted hazard ratio: 1.55 [95% CI, 1.14–2.09];
P
=0.005) but not evident in patients with PCI or PCI/CABG equipoise recommendation according to SYNTAX score II (adjusted hazard ratio: 0.94 [95% CI, 0.75–1.17];
P
=0.56). A similar risk of 5-year composite outcomes was observed between CABG and PCI with residual SYNTAX score ≤8.

Conclusions:
In this single-center retrospective study among patients with chronic total occlusion and multivessel disease, PCI was associated with higher risk of 5-year composite death, myocardial infarction, or stroke.
Racial Differences in XO (Xanthine Oxidase) and Mitochondrial DNA Damage-Associated Molecular Patterns in Resistant Hypertension
Authors: Butts Brittany , Brown Jamelle A. , Denney Thomas S. , Ballinger Scott , Lloyd Steven G. , Oparil Suzanne , Sanders Paul , Merriman Tony R. , Gaffo Angelo , Singh Jasvinder , Kelley Eric E. , Calhoun David A. , Dell’Italia Louis J. 
Published: February 2022

Background:
We previously reported increased plasma XO (xanthine oxidase) activity in patients with resistant hypertension. Increased XO can cause mitochondrial DNA damage and promote release of fragments called mitochondrial DNA damage-associated molecular patterns (mtDNA DAMPs). Here, we report racial differences in XO activity and mtDNA DAMPs in Black and White adults with resistant hypertension.

Methods:
This retrospective study includes 91 resistant hypertension patients (44% Black, 47% female) with blood pressure >140/90 mm Hg on ≥4 medications and 37 normotensive controls (30% Black, 54% female) with plasma XO activity, mtDNA DAMPs, and magnetic resonance imaging of left ventricular morphology and function.

Results:

Black-resistant hypertension patients were younger (mean age 52±10 versus 59±10 years;
P
=0.001), with higher XO activity and left ventricular wall thickness, and worse diastolic dysfunction than White resistant hypertension patients. Urinary sodium excretion (mg/24 hour per kg) was positively related to left ventricular end-diastolic volume (
r
=0.527,
P
=0.001) and left ventricular mass (
r
=0.394,
P
=0.02) among Black but not White resistant hypertension patients. Patients with resistant hypertension had increased mtDNA DAMPs versus controls (
P
<0.001), with Black mtDNA DAMPS greater than Whites (
P
<0.001). Transmission electron microscopy of skeletal muscle biopsies in resistant hypertension patients demonstrates mitochondria cristae lysis, myofibrillar loss, large lipid droplets, and glycogen accumulation.

Conclusions:
These data warrant a large study to examine the role of XO and mitochondrial mtDNA DAMPs in cardiac remodeling and heart failure in Black adults with resistant hypertension.
Improving Domain Repository Connectivity
Authors: Habermann Ted 
Published: February 2022

ABSTRACTDomain repositories, i.e. repositories that store, manage, and persist data pertaining to a specific scientific domain, are common and growing in the research landscape. Many of these repositories develop close, long-term communities made up of individuals and organizations that collect, analyze, and publish results based on the data in the repositories. Connections between these datasets, papers, people, and organizations are an important part of the knowledge infrastructure surrounding the repository.All these research objects, people, and organizations can now be identified using various unique and persistent identifiers (PIDs) and it is possible for domain repositories to build on their existing communities to facilitate and accelerate the identifier adoption process. As community members contribute to multiple datasets and articles, identifiers for them, once found, can be used multiple times.We explore this idea by defining a connectivity metric and applying it to datasets collected and papers published by members of the UNAVCO community. Finding identifiers in DataCite and Crossref metadata and spreading those identifiers through the UNAVCO DataCite metadata can increase connectivity from less than 10% to close to 50% for people and organizations.
Anathema und Übergabe an den Satan als Aktualisierungen des göttlichen Gerichts in den paulinischen Gemeinden
Authors: Zimmermann Christiane 
Published: February 2022

Abstract
Curses are an exegetically increasingly current topic. In this discussion the cultural-historical classification of these texts against the background of the Greek-Roman practice of cursing, in particular the defixiones, is central. The present contribution focuses on the Pauline use of the lexeme anathema (Gal 1:8–9; 1 Cor 16:22) and the syntagma “delivering to Satan” (1 Cor 5:5) against the background of their respective specific semantics, history of tradition, and contexts of reception. It sheds light on the theological dimension of these “curses,” whose effects beyond the Pauline letters can also be observed in the grave-robber curses from the context of the Galatian and Corinthian communities.
Her Body Healed
Authors: Soon Isaac T. 
Published: February 2022

Abstract
This article revives an accentuation of ιαται present in a number of medieval minuscules that has been neglected by most critical editions of the Greek New Testament since Erasmus. It argues that there is good external and internal evidence for reading ιαται in Mark 5:29 as the present tense-form (ἰᾶται) rather than the universally accepted perfect tense-form (ἴαται). The accentuation in medieval Greek witnesses provides both the present and the perfect as viable interpretations. Although the perfect ἴαται occurs dramatically less often than the present tense-form, the Markan text’s use of present tense-form verbs for indirect internal discourse strongly supports reading ιαται in Mark 5:29 as ἰᾶται, a reading that the Old Latin versions confirm. In light of the lexical semantics of ἰᾶται in ancient Greek literature and the OG, as well as the grammatical subject implied by ἰᾶται in Mark 5:29 (which the author argues to be the woman’s body), one should understand the verb as a passive middle.
Education, Health Care, and Poverty in Cuba
Authors: Rivera Isaias 
Published: February 2022

Abstract
Cuba’s economic integration into European socialist countries, led by the Soviet Union, offered the possibility of Cubans studying in these countries. A large number of professionals were trained in different fields. This at the same time created better opportunities and higher quality for the national education system at all levels due to academic mobility at all levels. To think about the term ‘revolution’ in Cuba, one must believe in a movement of ideas that promote progress. However, most of us in the Western world come to believe that progress has an equivalency of economic gain.
Spatial Patterns, Mechanisms, and Predictability of Barents Sea Ice Change
Authors: Efstathiou Elina , Eldevik Tor , Årthun Marius , Lind Sigrid 
Published: February 2022

AbstractRecent Arctic winter sea ice loss has been most pronounced in the Barents Sea. Here we explore the spatial structure of Barents Sea ice change as observed over the last 40 years. The dominant mode of winter sea ice concentration interannual variability corresponds to areal change (explains 43% of spatial variance) and has a center of action in the northeastern Barents Sea where the temperate Atlantic inflow meets the wintertime sea ice. Sea ice area import and northerly wind also contribute to this “areal-change mode”; the area increases with more ice import and stronger winds from the north. The remaining 57% variance in sea ice, individually and combined, redistributes the sea ice without changing the total area. The two leading redistribution modes are a dipole of increase in sea ice concentration south of Svalbard with decrease southwest of Novaya Zemlya, and a tripole of increase in the central Barents Sea with decrease east of Svalbard and in the southeastern Barents Sea. Redistribution is mainly contributed by anomalous wind and sea ice area import. Basic predictability (i.e., the lagged response to observed drivers) is predominantly associated with the areal-change mode as influenced by temperature of the Atlantic inflow and sea ice import from the Arctic.
Lithium plus antipsychotics or anticonvulsants for bipolar disorder: Comparing clinical response and metabolic changes
Authors: Köhler-Forsberg Ole , Sylvia Louisa G , Thase Michael , Calabrese Joseph R , Tohen Mauricio , Bowden Charles L , McInnis Melvin , Iosifescu Dan V , Kocsis James H , Friedman Edward S , Ketter Terence A , McElroy Susan L , Shelton Richard C , Fung Vicki , Ostacher Michael J , Nierenberg Andrew A 
Published: February 2022

Objective: Patients with bipolar disorder treated with lithium often require additional antipsychotics or anticonvulsants. However, the comparative effectiveness and safety of these agents as add-on to lithium has not been studied. Methods: This secondary analysis combined two similar 24-week trials on outpatients with bipolar disorder randomized to lithium (target serum level 0.4–0.6 mEq/L). Guideline-based adjunctive antipsychotics (Li+AP) and anticonvulsants (Li+AC) could be used if clinically indicated and was assessed at every study visit. Response was measured on the Clinical Global Impression scale and we performed adjusted mixed effects linear regression analyses. Analysis of variance tests compared metabolic measures including a binary diagnosis of metabolic syndrome before and after 24 weeks of treatment. Results: Among 379 outpatients (57% female, mean age 38 years, mean Clinical Global Impression 4.4), users of Li+AP ( N = 50, primarily quetiapine and aripiprazole) improved to a similar degree (mean Clinical Global Impression improvement = 1.6, standard deviation = 1.5) as those using lithium-only (i.e. without adjunctive antipsychotics or anticonvulsants, N = 149, mean Clinical Global Impression improvement = 1.7, standard deviation = 1.4) ( p = 0.59). Users of Li+AC ( N = 107, primarily lamotrigine and valproate, mean Clinical Global Impression improvement = 1.2, standard deviation = 1.3) and users of Li+AP+AC ( N = 73, mean Clinical Global Impression improvement = 1.1, standard deviation = 1.3) showed worse response compared to lithium-only users (all p < 0.01). When comparing Li+AP to Li+AC, users of Li+AP improved slightly better on general ( p = 0.05) and manic symptoms ( p = 0.01), but showed a worse development of glucose, triglycerides, and metabolic syndrome. Conclusion: Despite treatment-by-indication confounding, these findings are relevant for real-world treatment settings and emphasize the need for randomized trials on this clinically important topic.
Small Boat Recovery Task Performance in a Moving Environment
Authors: Fosha Rebecca A. , Matsangas Panagiotis , Cravalho Patrick F. , Thornburg Kristopher M. 
Published: February 2022

Objective Assess operator performance in a simulation of US Coast Guard small boat recovery to a larger vessel on a large scale, six degree-of-freedom, full motion simulator. Background Studies of human performance in small boat recovery task have never been conducted on a high amplitude, low frequency simulator. Empirical evidence of small boat recovery task performance in challenging motion conditions is needed to inform future maritime systems designs. Method Experienced active-duty boat crewmembers ( N = 13) conducted a small boat recovery task in three sea states on the Vertical Motion Simulator (VMS) at the NASA Ames Research Center. Task performance was assessed using a task equivalent for time to complete the task. Participant behaviors associated with increasing motion severity were observed. Results Task performance declined as motion conditions became more severe. Participants were more likely to use at least one hand to maintain balance during motion conditions, becoming more frequent with increasing motion severity. Many participants used one hand to complete the task despite contrary instructions and previous experience. Conclusion Two design recommendations were proposed to counter declining task performance in increasingly severe motion conditions. Handholds available to participants during the task, and task design supporting single handed completion were recommended for small boat recovery systems. Application This research is directly applicable to gross motor tasks requiring simultaneous maintenance of balance in a maritime environment, and may be extended to other environments where humans experience complex motions while completing tasks.
Depression and suicidal ideations in relation to occupational stress in a sample of Egyptian medical residents
Authors: Mohamed Mohamed Youssef , Elbatrawy Amira Naseeb , Mahmoud Dalia Abdel Moneim , Mohamed Mohamed Maged , Rabie Eman S 
Published: February 2022

Introduction: Medical students, interns, and residents have higher rates of depression than the general population, according to previous literature. Objective: The objectives of this paper were to determine the rate of depression and its severity in a group of Egyptian residents of Ain Shams University hospitals. Methods: This is a cross-sectional comparative study that took place in El-Demerdash Hospital from March 1, 2019 to September 1, 2020, with 220 Egyptian residents of Ain Shams University Hospitals participating. Results: The socioeconomic stress scale had a statistically significant relationship with depression scores ( p value = .008) and suicide scores ( p-value = .010), according to the findings. Additionally, there was a statistically significant relationship between suicide scores and depression scores ( p-value = .001). The relationship between obstetrics and gynecology and high suicide risk was statistically significant ( p value = .010), with obstetrics and gynecology having the highest percentage of high suicide risk (10 out of 19 residents, 52.63%), followed by pediatrics with 4 out of 11 residents (36.36%). Conclusion: The pediatrics department had the highest percentage of residents who were depressed, while the obstetrics and gynecology department had the highest suicide risk. Feeling underpaid, disruption of home life, having insufficient time, being concerned about keeping skills up to date, and having a large volume of work were also found to be the most stressful aspects of residency.
“I think that she would have wanted. . .”: Qualitative interviews with bereaved caregivers reveal complexity in measuring goal-concordant care at the end of life
Authors: Durieux Brigitte N , Berrier Anna , Catzen Hannah Z , Gray Tamryn F , Lakin Joshua R , Cunningham Rebecca , Morris Sue E , Tulsky James A , Sanders Justin J 
Published: February 2022

Background: Experts consider goal-concordant care an important healthcare outcome for individuals with serious illness. Despite their relationship to the patient and knowledge about the patient’s wishes and values, little is known about bereaved family caregivers’ perceptions of how end-of-life care aligns with patient goals and preferences. Aim: To understand caregivers’ perceptions about patients’ care experiences, the extent to which care was perceived as goal-concordant, and the factors that contextualized the end-of-life care experience. Design: Qualitative interview study employing a semi-structured interview guide based on the National Health and Aging Trends Survey end-of-life planning module. Template analysis was used to identify themes. Setting/participants: Nineteen recently bereaved family caregivers of people with serious illness in two academic medical centers in the Northeastern United States. Results: Most caregivers reported goal-concordant care, though many also recalled experiences of goal discordance. Three themes characterized care perceptions and related to perceived quality: communication, relationships and humanistic care, and care transitions. Within communication, caregivers described the importance of clear communication, inadequate prognostic communication, and information gaps that undermined caregiver confidence in decision making. Patient-clinician relationships enriched care and were considered higher-quality when felt to be humanistic. Finally, care transitions impacted goal discordance when marked by logistical barriers, a need to establish relationships with new providers, inadequate information transfer, and poor care coordination. Conclusions: Bereaved caregivers commonly rated care as goal-concordant while also identifying areas of disappointing and low-quality care. Communication, relationships and humanistic care, and care transitions are modifiable quality improvement targets for patients with advanced cancer.