bluuebunny/crossref_metadata_2025_split huggingface dataset:
High performance and resource efficient FFT processor based on CORDIC algorithm
Authors: Zhao Yupu , Lv Hong , Li Jun , Zhu Lulu 
Published: March 2022

AbstractFast Fourier Transform is widely used in communication and signal processing. I propose an improved multipath delay commutator pipelining architecture based on the radix-2 time decimation algorithm. By optimizing the intermediate data processing process and the first stage of pipelining, the architecture improves the system's computing speed and reduces the use of registers. I propose a multiplication scheme based on CORDIC and binary decomposition coding to realize complex number multiplication and constant multiplication and to eliminate the use of a multiplier. Experimental results suggest that proposed implementation has less latency and hardware utilization as compared to recently proposed implementations.
Rare earth element geochemistry in soils along arid and semiarid grasslands in northern China
Authors: Cao Yi-Wen , Liu Xiao-Ming , Wang Chao , Bai Edith , Wu Nanping 
Published: March 2022

Abstract
Background
Rare earth elements (REE) are a group of trace elements that behave geochemically coherently. REE fractionation patterns normalized to reference materials provide a powerful tool for documenting pedogenesis. In-soil processes are particularly difficult to illustrate with respect to contemporary and past climate conditions. In this study, we characterize the rare earth element (REE) contents in bulk soils and respective geochemical fractions (e.g., exchangeable, carbonate-bound, reducible, and oxidizable fractions) and to decipher the relationships between REE geochemistry components and climatic factors across a large-scale northern China transect (NCT).

Results
Across the NCT, bulk REE concentrations ranged from 55.2 to 241.1 μg g−1 with a main portion in the residual fraction (49–79%), followed by oxidizable fraction (2–40%), reducible fraction (3–22%), carbonate-bound fraction (0.1–16%), and negligible exchangeable fraction. The REE contents of geochemical components (carbonate-bound, reducible, and oxidizable) in topsoils correlated to climate factors (mean annual precipitation, mean annual temperature, potential evaporation, and aridity index (AI)). The normalized abundances to the upper continental crust (UCC) composition show that the middle REE was generally enriched than the light REE and heavy REE in topsoils along the transect. The overall UCC-normalized bulk REE patterns in topsoils and subsoils were similar, characterized by weak negative Ce anomalies and positive Eu anomalies.

Conclusions
Our data in topsoils and depth profiles collectively suggest that cycling of REE was primarily regulated by abiotic processes in area with AI < 0.2, while the biological effect on REE circulation in soil played a more effective role in area with AI > 0.3. The similar UCC normalized patterns in topsoils suggest that the REE was originated from a common source with limited influences from other sources (e.g., atmospheric dusts and anthropogenic contributions). Our results to some extent provide evidence for climatic influence REE distribution patterns both in topsoils and subsoils across the continental-scale transect. Our investigation gives insights into future studies on vertical REE mobility and its associated biogeochemical pathways.
Propagation of tau and α-synuclein in the brain: therapeutic potential of the glymphatic system
Authors: Lopes Douglas M. , Llewellyn Sophie K. , Harrison Ian F. 
Published: March 2022

AbstractMany neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease, are characterised by the accumulation of misfolded protein deposits in the brain, leading to a progressive destabilisation of the neuronal network and neuronal death. Among the proteins that can abnormally accumulate are tau and α-synuclein, which can propagate in a prion-like manner and which upon aggregation, represent the most common intracellular proteinaceous lesions associated with neurodegeneration. For years it was thought that these intracellular proteins and their accumulation had no immediate relationship with extracellular homeostasis pathways such as the glymphatic clearance system; however, mounting evidence has now suggested that this is not the case. The involvement of the glymphatic system in neurodegenerative disease is yet to be fully defined; however, it is becoming increasingly clear that this pathway contributes to parenchymal solute clearance. Importantly, recent data show that proteins prone to intracellular accumulation are subject to glymphatic clearance, suggesting that this system plays a key role in many neurological disorders. In this review, we provide a background on the biology of tau and α-synuclein and discuss the latest findings on the cell-to-cell propagation mechanisms of these proteins. Importantly, we discuss recent data demonstrating that manipulation of the glymphatic system may have the potential to alleviate and reduce pathogenic accumulation of propagation-prone intracellular cytotoxic proteins. Furthermore, we will allude to the latest potential therapeutic opportunities targeting the glymphatic system that might have an impact as disease modifiers in neurodegenerative diseases.
Casein phosphopeptide amorphous calcium phosphate and universal adhesive resin as a complementary approach for management of white spot lesions: an in-vitro study
Authors: Aref Neven S. , Alrasheed Maha Kh. 
Published: March 2022

AbstractBackgroundWhite spot lesion (WSL) is the most common consequence during and after orthodontic treatment. This study was conducted to investigate the ability of casein phosphopeptide amorphous calcium phosphate (CPP-ACP) coupled with universal adhesive resin to treat white spot lesions.Material and methodsForty-five extracted premolars were sectioned to create 90 specimens. Seventy-five specimens were demineralized to generate artificially created WSLs. Different strategies have been applied for the management of the artificially created WSLs. Six experimental groups were employed: Group I: sound enamel (control), Group II: demineralized enamel (artificially-created WSLs), Group III: ICON resin-treated WSLs, Group IV: CPP-ACP-treated WSLs, Group V: universal adhesive resin-treated WSLs, and Group VI: CPP-ACP followed by universal adhesive resin-treated WSLs. Assessment of color stability using a spectrophotometer, surface microhardness using a Vickers tester, and surface roughness using a profilometer was done. The surface topography of representative specimens from each experimental group was inspected using a scanning electron microscope. Collected data were analyzed using one-way ANOVA followed by Tukey’s post hoc test atp ≤ 0.05.ResultsWhite spot lesions treated with CPP-ACP and subsequently coated with universal adhesive resin (Group VI) exhibited a significantly lower ΔEthan both CPP-ACP (Group IV) and universal adhesive resin-treated (Group V) groups (p ≤ 0.05), but it was not significantly different from the ICON resin-treated group (Group III). For surface microhardness, WSLs treated with CPP-ACP and consequently coated with universal adhesive resin (Group VI) recorded the highest mean that was significantly different from both ICON resin (Group III) and universal adhesive resin-treated (Group V) groups (p ≤ 0.05). All the tested strategies (ICON resin, CPP-ACP, universal adhesive resin, and CPP-ACP followed by universal adhesive resin) significantly lowered the surface roughness of the WSLs (p ≤ 0.05), while no significant difference was detected among them.ConclusionsCombining a considerable caries remineralizing program using CPP-ACP with subsequent universal adhesive resin infiltration could be a promising approach to manage WSLs efficiently through increasing surface microhardness and restoring esthetic while developing a smoother surface.
Petrophysical characterization of the Los Humeros geothermal field (Mexico): from outcrop to parametrization of a 3D geological model
Authors: Weydt Leandra M. , Bär Kristian , Sass Ingo 
Published: March 2022

AbstractThe Los Humeros Volcanic Complex has been characterized as a suitable target for developing a super-hot geothermal system (> 350 °C). For the interpretation of geophysical data, the development and parametrization of numerical geological models, an extensive outcrop analogue study was performed to characterize all relevant key units from the basement to the cap rock regarding their petrophysical properties, mineralogy, and geochemistry. In total, 226 samples were collected and analyzed for petrophysical and thermophysical properties as well as sonic wave velocities and magnetic susceptibility. An extensive rock property database was created and more than 20 lithostratigraphic units and subunits with distinct properties were defined. Thereby, the basement rocks feature low matrix porosities (< 5%) and permeabilities (< 10–17 m2), but high thermal conductivities (2–5 W m−1 K−1) and diffusivities (≤ 4·10–6 m2s−1) as well as high sonic wave velocities (≥ 5800 m s−1). Basaltic to dacitic lavas feature matrix porosities and permeabilities in the range of < 2–30% and 10–18–10–14 m2, respectively, as well as intermediate to low thermal properties and sonic wave velocities. The pyroclastic rocks show the highest variability with respect to bulk density, matrix porosity (~ 4– > 60%) and permeability (10–18–10–13 m2), but feature overall very low thermal conductivities (< 0.5 W m−1 K−1) and sonic wave velocities (~ 1500–2400 m s−1). Specific heat capacity shows comparatively small variations throughout the dataset (~ 700–880 J kg−1 K−1), while magnetic susceptibility varies over more than four orders of magnitude showing formation-related trends (10–6–10–1 SI). By applying empirical correction functions, this study provides a full physiochemical characterization of the Los Humeros geothermal field and improves the understanding of the hydraulic and thermomechanical behavior of target formations in super-hot geothermal systems related to volcanic settings, the relationships between different rock properties, and their probability, whose understanding is crucial for the parametrization of 3D geological models.
University students’ satisfaction and future outlook towards forced remote learning during a global pandemic
Authors: Abdullah Siti Intan Nurdiana Wong , Arokiyasamy Klara , Goh Sock Leng , Culas Andrea Joveena , Manaf Nor Masheera Abdul 
Published: March 2022

AbstractTechnology has enabled the higher education ecosystem to tailor to the students who have diverse needs and to engage with them remotely, especially when face-to-face interaction is not possible. This research contributes knowledge in forced remote learning during the unprecedented global pandemic situation of Covid-19. Using a cross-sectional quantitative method, a total of 480 respondents among undergraduate students from five private universities in Malaysia participated in this study. The data was analysed using structural equation modelling and results indicated that online feedback, online future relevance, online interaction, online teaching effectiveness, and personal well-being were statistically significant in influencing students’ satisfaction. Moreover, online learning satisfaction directly predicted 68.3% of the students’ continuous usage intention while their usage intention was heightened with higher levels of proficiency in online learning. Students’ satisfaction was found to be a significant mediator between all the factors towards usage intention except online assessment, online support, and personal well-being. This study provides the higher education institutions with insights to continuously improve their online delivery strategies and bridge the gap with their students during the pandemic crisis.
Public health critical race praxis at the intersection of traffic stops and injury epidemiology
Authors: Fliss Michael Dolan , Baumgartner Frank R. , Delamater Paul , Marshall Steve W. , Poole Charles , Robinson Whitney 
Published: March 2022

Abstract
Background
Law enforcement traffic stops are one of the most common entryways to the US justice system. Conventional frameworks suggest traffic stops promote public safety by reducing dangerous driving practices and non-vehicular crime with little to no collateral damage to individuals and communities. Critical frameworks interrogate these assumptions, identifying significant individual and community harms that disparately impact Black, Indigenous, and People of Color (BIPOC) and low-income communities.

Methods
The Public Health Critical Race Praxis (PHCRP) and multi-level frameworks from community anti-racist training were combined into a structured diagram to guide intervention and research teams in contrasting conventional and critical perspectives on traffic stops. The diagram divides law enforcement and drivers/residents as two separate agent types that interact during traffic stops. These two agent types have different conventional and critical histories, priorities, and perspectives at multiple levels, including individual, interpersonal, institutional, and cultural levels. Conventional solutions (identifying explicitly racist officers, “meet-a-cop” programs, police interaction training for drivers) are born from conventional frameworks (rewarding crime prevention regardless of cost, the war on drugs saves lives, driver behavior perfectionism). While conventional perspectives focus on individual and interpersonal levels, critical perspectives more deeply acknowledge dynamics at institutional and cultural levels. Critical solutions may be hard to discover without critical frameworks, including that law enforcement creates measurable collateral damage and disparate social control effects; neighborhood patrol priorities can be set without community self-determination or accountability and may trump individual and interpersonal dynamics; and the war on drugs is highly racialized and disproportionally enforced through traffic stop programs.

Conclusions
Traffic stop enforcement and crash prevention programs that do not deeply and critically consider these dynamics at multiple levels, not just law enforcement-driver interactions at the individual and interpersonal levels, may be at increased risk of propagating histories of BIPOC discrimination. In contrast, public health and transportation researchers and practitioners engaged in crash and injury prevention strategies that employ law enforcement should critically consider disparate history and impacts of law enforcement in BIPOC communities. PHCRP, anti-racism frameworks, and the included diagram may assist them in organizing critical thinking about research studies, interventions, and impacts.
The French Ankle Ligament Reconstruction - Return to Sport after Injury (ALR-RSI-Fr) is a valid scale for the French population
Authors: Ajaka Nahi , Bouché Pierre-Alban , Dagher Michel , Lopes Ronny , Bauer Thomas , Hardy Alexandre 
Published: March 2022

Abstract
Purpose
The aim of this study was to translate, adapt and validate in French the Ankle Ligament Reconstruction - Return to Sport after Injury (ALR-RSI), a 12-item English language scale assessing the psychological impact of returning to sports after ACL reconstruction. Our hypothesis was that the French version of the ALR-RSI scale would be valid and adaptable to the French population.

Methods
The procedure followed the guidelines for the intercultural adaptation of the self-administered questionnaires. A version of the ALR-RSI-Fr questionnaire was validated according to the international guidelines of COSMIN (COnsensus-based Standards for the selection of health status Measurement INstruments). A prospective study was conducted between March 2020 and June 2021. The study included two population groups, the first one being that of adult athletes of all levels who underwent arthroscopic ankle ligament reconstruction and the second being that of adult athletes who did not suffer from any ankle problems. After consent, patients completed three questionnaires, the ALR-RSI-Fr, the AOFAS and the Karlsson score.

Results
The study included 30 patients and 30 controls who were all athletes. The mean age of the patients was 34.6 with 60% male and 40% female. The average time for patients to return to sport was 5.6 months. Twenty-nine patients (96.6%) underwent arthroscopic ankle reconstruction while only one was eligible for ligament reinsertion. The control group with demographic data matched to the patient group was included in this study.
Correlations between ALRSI, the total Karlsson score and its different sub items and the AOFAS were estimated using Spearman coefficients. Discriminant validity was tested between the “patient” and “control” groups and sub-groups using the Wilcoxon tests. Reliability was evaluated on the ρ intraclass correlation coefficient (ICCC). A strong correlation was noted between the ALR-RSI-Fr , Karlsson and AOFAS with a Spearman score of 0.90 [0.76-0.96].A highly significant difference was found between the "patient" and "control" groups. The internal consistency of the questionnaire was excellent with a Cronbach's alfa of 0.94. Reproducibility was "excellent" with an interclass correlation coefficient of q = 0.97 [0.94-0.99].

Conclusion
This study showed that the cross-cultural adaptation of the English version of the ALR-RSI was successful and validated for the French-speaking population. The discriminant capacity of the scale between patients who underwent reconstruction and healthy subjects was also confirmed. This questionnaire will allow surgeons to better evaluate the psychological impact of returning to sports after ankle ligament reconstruction in French speaking patients

Level of evidence
LEVEL II: Prospective cohort study (patients enrolled at different points in their disease) Control arm of randomized trial.
On the value and limitations of incorporating a “clean phase” into the surgical treatment of prosthetic joint infections – an illustrative cadaveric study using fluorescent powder
Authors: Vles Georges , Bossen Jeroen , Kloos Johannes , Debeer Philippe , Ghijselings Stijn 
Published: March 2022

Abstract
Purposes
A septic revision of an artificial joint is routinely split up in a so-called dirty phase and a clean phase. The measures taken to initiate the start of the clean phase vary significantly between musculoskeletal infection centers. We performed simulations of one-step exchanges of infected THAs and sought to 1) determine the effect of different clean phase protocols on the sterile field, and 2) determine whether or not it is possible to re-implant the new prosthesis completely clean.

Methods
Nine fresh frozen cadaveric hips were used and primary THA was undertaken via a direct anterior approach. Before implantation of the components varying amounts of fluorescent powder (GloGerm) were deposited, simulating bacterial infection. Second, a one-step exchange was performed via a posterolateral approach. After implant removal, debridement, and lavage, randomization determined which clean phase protocol was followed, i.e. no, some or full additional measures. Finally, the new prosthesis was re-implanted.
In order to determine the effect of different clean phase protocols on contamination of the sterile field standardized UV light-enhanced photographs were obtained of 1) the gloves, 2) the instrument table, 3) the drapes, and 4) the wound and these were ranked on cleanliness by a blinded panel of hip surgeons.
In order to determine whether or not it is possible to re-implant the prosthesis completely clean, the implant was taken out again at the end of the one-step exchange and inspected for contamination under UV light.

Results
The gloves, the instrument table, the drapes and the wound were significantly cleaner after a clean phase using full additional measures compared to partial or no additional measures (p < 0.000). Partial measures were able to reduce some of the contamination of the gloves and the wound, but had no effect on the drapes and the instrument table. All re-implanted implants were contaminated with some amount of fluorescent powder at the end of the one-step exchange.

Conclusions
We advise to incorporate a clean phase with full additional measures into the surgical treatment of prosthetic joint infections, as partial measures seem to be a poor compromise.

Level of evidence
Not applicable (cadaveric study).
Valorization of porcine by-products: a combined process for protein hydrolysates and hydroxyapatite production
Authors: Borges Sandra , Piccirillo Clara , Scalera Francesca , Martins Rui , Rosa Ana , Couto José António , Almeida André , Pintado Manuela 
Published: March 2022

AbstractThe meat industry generates large amounts of by-products that are costly to be treated and discarded ecologically; moreover, they could be used to extract high added-value compounds. In this work, we present an innovative combined process which allowed the parallel extraction of both organic and mineral compounds; more specifically protein hydrolysates and single-phase hydroxyapatite were obtained. The protein hydrolysates, extracted through an enzymatic hydrolysis with alcalase, showed a degree of hydrolysis of 53.3 ± 5.1%; moreover, they had a high protein content with peptides with molecular weight lower than 1.2 kDa. Their antioxidant activities, measured with ABTS and ORAC tests, were 21.1 ± 0.5 mg ascorbic acid equivalent/g of dry extract and 87.7 ± 6.3 mg Trolox equivalent/g of dry extract, respectively. Single-phase hydroxyapatite, obtained with a simple calcination at 700 °C on the residues of the hydrolysis process, showed a Ca/P ratio close to the stoichiometric one (1.65 vs. 1.67) and presented a nanometric structure. This study reports a simple and feasible process for the valorization of porcine by-products in a large-scale up generating products with potential applications for environment remediation, biomedicine, nutrition and catalysis/bioenergy.
Graphic Abstract
Effects of Plyometric Training on Lower Body Muscle Architecture, Tendon Structure, Stiffness and Physical Performance: A Systematic Review and Meta-analysis
Authors: Ramírez-delaCruz María , Bravo-Sánchez Alfredo , Esteban-García Paula , Jiménez Fernando , Abián-Vicén Javier 
Published: March 2022

Abstract
Background
Plyometric training (PT) has been widely studied in sport science. However, there is no review that determines the impact of PT on the structural variables and mechanical properties of the lower limbs and physical performance.

Objective
The aim of this systematic review and meta-analysis was to determine the effects of PT on lower body muscle architecture, tendon structure, stiffness and physical performance.

Methods
Five electronic databases were analysed. The inclusion criteria were: (1) Availability in English; (2) Experimental studies that included a PT of at least eight sessions; and (3) Healthy adults subjects. Four meta-analyses were performed using Review Manager software: (1) muscle architecture; (2) tendon structure; (3) muscle and tendon stiffness; (4) physical performance.

Results
From 1008 search records, 32 studies were eligible for meta-analysis. Muscle architecture meta-analysis found a moderate effect of PT on muscle thickness (Standard Mean Difference (SMD): 0.59; [95% Confidence Interval (CI) 0.47, 0.71]) and fascicle length (SMD: 0.51; [95% CI 0.26, 0.76]), and a small effect of PT on pennation angle (SMD: 0.29; [95% CI 0.02, 0.57]). The meta-analysis found a moderate effect of PT on tendon stiffness (SMD: 0.55; [95% CI 0.28, 0.82]). The lower body physical performance meta-analysis found a moderate effect of PT on jumping (SMD: 0.61; [95% CI 0.47, 0.74]) and strength (SMD: 0.57; [95% CI 0.42, 0.73]).

Conclusion
PT increased the thickness, pennation angle and fascicle length of the evaluated muscles. In addition, plyometrics is an effective tool for increasing tendon stiffness and improving jump and strength performance of the lower body.