bluuebunny/crossref_metadata_2025_split huggingface dataset:
Walking, SD and urinary tract symptoms with BPH: A cross-sectional, retrospective and follow-up chain design study
Authors: Zhang LinLin , Hao Chunli , Liu Lei , Zou Hao , Jiang Dongxu , Wang Lei 
Published: October 2022

Abstract
BACKGROUND: Lower urinary tract symptoms (LUTSs) are the most common problem in older men with benign prostatic hyperplasia (BPH). Physical activity and sedentariness may be important LUTS risk factors and suitable targets for intervention. However, what is the most effective way to engage in physical activity? There is still no consensus among academics.
OBJECTIVE: To observe which of the two different physical activity modalities, square dancing (SD) or walking, is more effective in delaying the effects of LUTSs/BPH in older men and to provide a basis for promoting active participation in appropriate physical activity for BPH patients.
DESIGN: This study was a chain design study with cross-sectional (June 2018), retrospective (from June 2014 to June 2018) and follow-up (June 2018 to June 2020) components for LUTSs.
PARTICIPANTS: Men aged 60 and over who could perform physical activity alone and lived in the same community.
MAIN MEASURES: The effect of different forms of physical activity on the alleviation of LUTSs in BPH patients was observed retrospectively; the main physical activity patterns of older adults in the town were walking and SD. Therefore, the two physical activity modalities of walking and SD were used as the main study factors, and the propensity score 1:1 matching method was applied to control for confounding factors in the retrospective cohort, which was divided into walking and SD groups to compare the clinical progression of LUTSs in the two groups. The time between study entry into the cohort and LUTS progression (appearance or exacerbation of symptoms) was used as the outcome to determine whether LUTS progression occurred in the two groups. The Cox proportional hazards model was applied to analyze the effect of walking and SD on the delay in the clinical progression of LUTSs/BPH in older men.
KEY RESULT: Multifactorial Cox regression analysis showed that patients in the square dancing group had a 0.41-fold lower risk of LUTSs than those in the walking group (HR=0.41, 95% CI: 0.19-0.88, p=0.02).
CONCLUSIONS: SD can more effectively delay the clinical progression of LUTSs in BPH patients, and the results of this study provide a good reference for the selection of self-guided physical activity intervention modalities for BPH patients.
Comparison of the retromolar space in adults with different sagittal skeletal types and eruption patterns of the mandibular third-molar
Authors: Gao Qianya , Zhou Xiaohui , Chen Baoyi , Huang Min , Lin Huiyi , Guo Weiqi , Tsay T. Peter , Liu Chang 
Published: October 2022

Abstract
Background: The retromolar space (RMS) has not been investigated in patients with different skeletal classes and third-molar eruption patterns. The objective of this study was to test the null hypothesis that there is no difference in the mandibular RMS among normodivergent subjects with different skeletal Classes and third-molar eruption patterns using cone-beam computed tomography (CBCT).
Method: A total of 105 normodivergent patients (20-40years) were included in this study. Patients were categorized into Class Ⅰ, Ⅱ and Ⅲ groups based on ANB, and they were further categorized into third-molar impacted and erupted groups. The RMS was measured at four planes parallel to the occlusal plane along the cuspal and sagittal line. The RMS was compared among the three sagittal groups and between impacted and erupted groups.
Results: The skeletal Class II group showed statistically smaller RMS (P<0.05). The RMS was larger in third-molar erupted group(P<0.05). The rates of root contact and third-molar impaction was significantly higher in Class II group. (P<0.05)
Conclusions: The null hypothesis was rejected. Skeletal Class II patients have smaller RMS and higher rates of root contact and mandibular third-molars impaction. The presence of impacted mandibular third molars was observed to be associated with shorter RMS. As such, the RMS should be verified with CBCT before molar distalization, especially in patients with Skeletal Class II relation and third-molar impaction.
Functional and mortality outcomes with medical and surgical therapy in malignant posterior circulation infarcts: A systematic review
Authors: Lim Nicole-Ann , Lin Hong-Yi , Tan Choon Han , Ho Andrew FW , Yeo Tseng Tsai , Nga Vincent , Tan Benjamin YQ , JR Mervyn , Yeo Leonard LL 
Published: October 2022

Abstract

Background
There remains uncertainty regarding optimal definitive management for malignant posterior circulation infarcts (MPCI). While guidelines recommend neurosurgery for malignant cerebellar infarcts that are refractory to medical therapy, concerns exist about functional outcome and quality of life after decompressive surgery.
Objective
This study aims to evaluate the outcomes of surgical intervention compared to medical therapy in MPCI.
Methods
In this systematic review, MEDLINE, Embase and Cochrane databases were searched from inception until 2nd April 2021. Studies were included if they involved posterior circulation strokes treated with neurosurgical intervention, and reported mortality and functional outcome data. Data were collected according to PRISMA guidelines.
Results
The search yielded 6,677 studies of which 31 studies (comprising 723 patients) were included for analysis. From the included studies, we found that surgical therapy led to significant differences in mortality and functional outcomes in patients with severe disease. Neurological decline and radiological criteria was often used to decide the timing for surgical intervention, as there is currently limited evidence for preventative neurosurgery. There is also limited evidence for the superiority of one surgical modality over another.
Conclusion
For patients with MPCI, in terms of mortality and functional outcome, surgical therapy appears to be equivocal to medical therapy, except in patients with severe disease. Reliable evidence is lacking and further prospective studies are rendered.
Response surface methodology approach for dyeing process optimization of Ayous (Triplochiton scleroxylon) wood with acid dye
Authors: Wu Shiqian , Peng Limin , Fu Feng , Feng Yun , He Jinrong , Wang Huishan 
Published: October 2022

Abstract

Dyeing of wood is an important value-adding process. An important indicator in the assessment of the performance of wood dyeing process is the dye penetration. In present study, the existing method of response surface methodology was extended to study the dyeing process optimization of Ayous (Triplochiton scleroxylon) wood with acid dye using the radial dye penetration rate as an indicator. The experiments were carried out on the basis of a single factor experiment, and the optimal condition was determined by means of the Box-Behnken Design of response surface methodology. The effects of temperature, dye concentration, dyeing time and accelerant mass fraction on the radial dye penetration rate of Ayous wood were optimized. The experimental results showed that the maximum radial dye permeability can be achieved under optimum dyeing temperature (86.03oC), dye concentration (0.31%), dyeing time (8 h), and accelerant mass fraction (2.23%). Under these conditions, the maximum dye-uptake and radial dye penetration rate were found to be 14.28% and 22.34%, respectively. The results of analysis of variance indicated that the mathematical model proposed in this study can be used to predict the dye-uptake and radial dye penetration rate of acid dye on Ayous wood by changing the process parameters.
Hydro-geochemistry and irrigation water quality of groundwater in Chhattisgarh plain central India
Authors: Lal Bharat , Nayak Vinod , Shukla Abhishek Kumar , Kumar Pavan 
Published: October 2022

Abstract
The current study was conducted with sampling of eighty-four groundwater sample which was used for analyzing various physico- chemical properties in groundwater to assess the status of irrigation water quality and their hydro-geochemistry.For this purpose, different ionic concentration pH, EC, TDS, TH, Ca2+, Mg2+, Na+, K+, Cl−, SO42−, CO32− and HCO3− were determine in groundwater and used to calculate the various irrigation water quality parameters like SAR, Na %, RSC, MHR, KR, PI%, PS and RSBC. The groundwater sample pH was ranged from 7.9 to 9.3 with having electrical conductivity of 90 µS/cm to 2000 µS/cm. Among the all-sampled groundwater 2.38%, 1.19%, 5.95%, 16.67%, and 2.38% water samples were unsuitable for irrigation water due to having high loading of PI, KR, MHR, RSC and PS value, respectively. The ionic concentration orders werefound in terms of cations Ca2+> Na+> Mg2+> K+ and anions HCO3−> Cl−> SO42−in groundwater. The piper trilinear diagram suggested Ca (Mg)- HCO3−, Ca (Mg)-Cl− and mixed type water was dominated in the study area. The Gibbs and other bivariate plot were indicated that the silicate weathering and ion exchange phenomenafrom rock water interaction was mainly responsible for the different ion’s sources in groundwater instead of evaporite and carbonate dissolutions.
Systematic literature review on nutritional habits of 0–6-year-olds with early childhood caries (ECC)
Authors: Antoniou Sophie , Antoniou Sophie , Naeem Samah 
Published: October 2022

Abstract
This systematic review aims to highlight potential areas of importance within a child’s diet that play a primary role in their development of early childhood caries. Caries is a multifactorial disease, influenced by a number of factors including, oral hygiene, degree of mineralisation of teeth, salivary flow rates in addition to dietary factors.
This review will specifically focus on the nutritional aspect involved in the pathogenesis of caries. Targeting the main dietary risk factors will aid in the prevention of ECC and severe early childhood caries (SECC), with an overall aim to reduce the DMFT (Decayed Missing and Filled Teeth) in children. This is of particular relevance to the secondary dentition of these children, as those with ECC are much more likely to develop caries and subsequent infections in their adolescence and adulthood also (1), further underlining the immense significance of prevention.
Background information:
There is universal recognition that consumption of free sugars and fermentable carbohydrates heavily precipitates the development of caries. However, a holistic approach to diet including all food groups needs to be investigated to devise an easy to follow and nutritionally balanced guide for caregivers to utilise when providing nourishment to children under 6. Examining the diet as such, gives a further understanding of its holistic contribution to the development of caries, rather than examining sugar intake and frequency alone.
Aims:
To construct a dietary proposal for public dissemination based on nutritional and dental recommendations for children under 6.
Objectives:
To evaluate the various dietary habits implicated in the development of ECC and how they interact with the indirect factors that also predispose children under 6 to ECC.
Management of Alternaria blight (Alternaria alternata) of tomato through novel combined formulations of fungicides
Authors: SHARMA RATAN LAL , Ahir R. R. , Sharma Astha , Ghasolia R. P. , Kumar Naresh , sharma pinki 
Published: October 2022

Abstract
The present investigation aimed to find the most efficient and novel combined formulation of fungicides belonging to triazole and strobilurin groups for managing Alternaria blight (Alternaria alternata) of tomato under open field conditions. Efficacy of seven fungicides like propineb, hexaconazole, propiconazole, azoxystrobin, mancozeb, tebuconazole + trifloxystrobin and carbendazim + mancozeb was evaluated in vitro and in vivo. In vitro study was carried out through poisoned food technique, while field experiment was conducted for two consecutive years (2017 and 2018) at Jobner (Jaipur), India. Two foliar sprays were applied at 45 and 60 days after transplanting (DAT), and disease intensity was recorded at 75 DAT. Hexaconazole (@ 300 and 500 ppm) completely inhibited mycelial growth, followed by tebuconazole + trifloxystrobin (@ 500 ppm). In field conditions, two foliar sprays of hexaconazole (@ 0.2%) at 15 days intervals provided maximum disease reduction (79.74%) with increased fruit yield (88.51%) over control, followed by tebuconazole + trifloxystrobin (76.33% and 82.35%, respectively). Alternaria blight is one of the significant biotic stresses that limit crop productivity and grower's prosperity. Systemic fungicides, particularly triazoles, play a substantial role in preventing infection by Alternaria sp. Thus, two foliar sprays of hexaconazole (0.2%) at 15 days intervals reduced disease intensity effectively with increased fruit yield and profitability.
U-Sleep: resilient to AASM guidelines
Authors: Fiorillo Luigi , Monachino Giuliana , Meer Julia van der , Pesce Marco , Warncke Jan , Schmidt Markus , Bassetti Claudio , Tzovara Athina , Favaro Paolo , Faraci Francesca 
Published: October 2022

Abstract
AASM guidelines are the results of decades of efforts aiming at standardizing sleep scoring procedure, in order to have a commonly used methodology. The guidelines cover several aspects from the technical/digital specifications, e.g., recommended EEG derivations, to detailed sleep scoring rules accordingly to age. In the context of sleep scoring automation, deep learning has demonstrated better performance compared to many other techniques. Usually, clinical expertise and official guidelines are fundamental to support automated sleep scoring algorithms in solving the task. In this paper we show that a deep learning based sleep scoring algorithm may not need to fully exploit the clinical knowledge or to strictly follow the AASM guidelines. Specifically, we demonstrate that U-Sleep, a state-of-the-art sleep scoring algorithm, can be strong enough to solve the scoring task even using clinically non-recommended or non-conventional derivations, and with no need to exploit information about the chronological age of the subjects. We finally strengthen a well-known finding that using data from multiple data centers always results in a better performing model compared with training on a single cohort. Indeed, we show that this latter statement is still valid even by increasing the size and the heterogeneity of the single data cohort. In all our experiments we used 28528 polysomnography studies from 13 different clinical studies.
Software Fault Prediction Using Deep Learning Techniques
Authors: Batool Iqra , Khan Tamim Ahmed 
Published: October 2022

Abstract
Software fault prediction (SFP) techniques are used to identify faults at the early stages of the software development life cycle (SDLC). We find machine learning techniques as commonly used techniques for SFP as compared to deep learning methods which can produce more accurate results. Deep learning offers exceptional results in a variety of domains such as computer vision, natural language processing, speech recognition, etc. In this study, we use three deep learning methods, namely, Long Short Term Memory (LSTM), Bidirectional LSTM (BILSTM), and Radial Basis Function Network (RBFN) to predict software faults and compare our results with existing models to show how our results are more accurate. In our study, we use Chidamber and Kemerer (C&K) metrics-based datasets to conduct experiments and test our proposed algorithm. We conclude that LSTM and BILSTM perform better whereas RBFN is faster in producing the required results. We use k-fold cross validation to do the model evaluation. Our proposed models provide a more accurate and efficient SFP mechanism to software developers.
Identification of an Autophagy-Related Signature for Predicting Prognoses and Immune Activity in Pancreatic Cancer metastasis
Authors: Deng Qianxi , Wu Linju , He Jin , Wu Fan , Jiang Zheng 
Published: October 2022

Abstract
Background
Although autophagy is crucial in cancer metastasis, the role of genes in the autophagy process in pancreatic cancer metastasis and prognosis remains uncertain. The study intended to identify ARGs associated with cancer metastasis and construct an ARGs prognostic model for pancreatic cancer patients.
Methods
Differentially expressed ARGs (DEARGs) were identified in GEO (the Gene Expression Omnibus) database and HADb (the Human Autophagy Database). TCGA (The Cancer Genome Atlas) database and real time-PCR was applied to validate the expression of these genes. Univariate and LASSO Cox regression analyses were applied to screen OS (overall survival) related DEARGs (p < 0.05) as hub genes. A 5-ARGs prognostic model was constructed. Five ARGs were further analyzed to recognize underlying small-molecule drugs in the L1000FWD database and performed by GO (Gene Ontology) and KEGG (Kyoto Encyclopedia of Genes and Genomes) analyses. Moreover, CIBERSORT and ESTIMATE were performed to match immune-infiltrating cells between the primary and metastasis groups. Correlation analysis demonstrated potential regulatory pathways between 5 ARGs and significant immune cell subsets.
Result
We filtrated twenty-two DEARGs and screened five OS-related ARGs (CASP1, RHEB, CHMP2B, MYC, HDAC6) as hub genes. A 5-ARGs prognostic model was built, calculating risk scores and dividing the low- and high-risk groups by the median. The low-risk group was markedly longer OS than the high-risk group in TCGA-PAAD cohort. Moreover, the 5-ARGs prognostic model was more precise than the clinicopathological characteristics. Function enrichment analysis showed that 5 ARGs were involved in the autophagy-related pathway. We identified several potential small-molecule compounds targeting ARGs. The ESTIMATE analysis showed the metastasis group was a significantly lower ESTIMATE score than the primary group. CIBERSORT analysis showed a higher percentage of Treg cells in the metastasis group. In the PCA analysis, immune cell subsets were signally diverse between the two groups. In addition, Treg cell was statistically associated with RHEB (r = -0.67, p = 0.049), CHMP2B (r = -0.7, p = 0.035), MYC (r = -0.75, p = 0.019).
Conclusion
Our results demonstrated that ARGs might participate in the metastasis process of pancreatic cancer by regulating autophagy and immune infiltration, further identifying potential drugs for pancreatic cancer. Simultaneously, the 5-ARGs prognostic model might be a promising prognostic model for pancreatic cancer patients.
Antibiotic Resistance Profile of Common Uropathogens during COVID-19 Pandemic: Hospital based Epidemiologic Study
Authors: Gawad Ahmed M. Abdel , Ashry Walaa Mohamed Omar , El-Ghannam Sherief , Hussein Mahmoud , Yousef Ahmed 
Published: October 2022

Abstract

Background: Antimicrobial resistance has a direct impact on the ability to treat common infections, and this was worsened during the COVID-19 pandemic. Worldwide surveillance studies are lacking and resistance rates vary spatially, so frequent local surveillance reports are required to guide antimicrobial stewardship efforts.
This study aims to report our common local uropathogens and their antibiogram profiles in our community during the COVID era.
Methods: A retrospective study included patients referred to our urology units with urine culture and sensitivity. All bacterial strains were identified, and their antibiotic susceptibilities were tested.
Results: Out of 2581 urine culture results recruited, 30% showed microbiological proof of infection. The majority, 486 (63.4%), were isolated from females. The most frequent isolates were Escherichia coli (44.4%) and S. aureus (17.8%). The resistance rates ranged from 26.9 to 76.9%. Piperacillin-tazobactam antibiotic had the lowest resistance rate. The multi-drug resistance pattern was recorded in 181 (23.9%) of the isolates; 159/597 (26.6%) Gram-negative and 22/160 (13.8%) Gram-positive isolates.
Conclusions: Alarming rates of antimicrobial resistance were detected, which stresses the significance of following infection control policies and establishing national antimicrobial stewardship standards.
Flash flood susceptibility mapping in Alipurduar district using multi-criteria decision analysis approach
Authors: BISWAS SANJAY , MITRA RAJIB , ROY DIPESH , MANDAL DEEPAK KUMAR 
Published: October 2022

Abstract
One of the worst climate-related natural disasters in the world is flash flooding. The present study has integrated the Geographic information system (GIS) and Analytical hierarchy process (AHP) method for mapping the flash flood susceptibility zones of the Sub-Himalayan Alipurduar district of West Bengal, India. The study applied eleven flood conditioning factors, and weights have been assigned for them based on the expert's opinion to compute the AHP. The flash flood susceptibility map depicted four zones, viz., (a) flash flood free zone, (b) low flash flood susceptibility zone, (c) moderate flash flood susceptibility zone, and (d) high flash flood susceptibility zone. The research found that 7.98% area of the district was highly susceptible to flash floods, and only 3.93% area into a flash flood free zone. Out of six community development blocks of the district, three blocks were highly susceptible to flash floods disaster, i.e., Madarihat, Kalchini, and Kumargram. The produced map was also validated with the field photographs and flash flood inventory map of the district. This kind of study is always helpful in mitigating the intensity of such a kind of disaster and can play a precious role in achieving sustainable development goals.
Enhanced Adsorption and Photocatalytic Degradation of Methylene Blue Using S-TiO 2 Composites Pillared Clay under Visible Light
Authors: Natsir Muh. , Irwan Irwan , Azis Thamrin , Wati Irma , Maulidiyah Maulidiyah , Salim La Ode Agus , Arham Zul , Bijang Catherina M. , Nurdin Muhammad 
Published: October 2022

Abstract
We investigated methylene blue adsorption capacity and photodegradation removal efficiency using an S-TiO2@clay composite by irradiating a commercial Tungsten halogen lamp in a reactor. The same experimental conditions were applied to clay and pristine TiO2 as a reference. Morphology surface area, chemical bonding, and optical properties of those samples were characterized by using FESEM, FTIR and UV-Vis DRS tehcniques. The S-TiO2@clay composites showed a high surface area and an even pore distribution compared to natural clays and pristine TiO2. The results indicate that the composite was successfully pillared on natural clay. These results exhibit that S-TiO2 composite pillared natural clay (S-TiO2@clay) presented better results in the methylene blue dye adsorption-photodegradation process, with an adsorption efficiency of 93.87% and degradation efficiency of 94.94%. In tests performed in the absence of natural clay, the degradation efficiency of 88.46%, while tests performed in the natural clay only obtained an adsorption efficiency of 86.41%. These results evidence that the combination methods of adsorption-photodegradation are very efficient in removing methylene blue dye.