bluuebunny/crossref_metadata_2025_split huggingface dataset:
RGB camera-based simultaneous measurements of percutaneous arterial oxygen saturation, tissue oxygen saturation, pulse rate, and respiratory rate
Authors: Nishidate Izumi , Yasui Riku , Nagao Nodoka , Suzuki Haruta , Takara Yohei , Ohashi Kaoru , Ando Fuminori , Noro Naoki , Kokubo Yasuaki 
Published: September 2022

We propose a method to perform simultaneous measurements of percutaneous arterial oxygen saturation (SpO2), tissue oxygen saturation (StO2), pulse rate (PR), and respiratory rate (RR) in real-time, using a digital red–green–blue (RGB) camera. Concentrations of oxygenated hemoglobin (CHbO), deoxygenated hemoglobin (CHbR), total hemoglobin (CHbT), and StO2 were estimated from videos of the human face using a method based on a tissue-like light transport model of the skin. The photoplethysmogram (PPG) signals are extracted from the temporal fluctuations in CHbO, CHbR, and CHbT using a finite impulse response (FIR) filter (low and high cut-off frequencies of 0.7 and 3 Hz, respectively). The PR is calculated from the PPG signal for CHbT. The ratio of pulse wave amplitude for CHbO and that for CHbR are associated with the reference value of SpO2 measured by a commercially available pulse oximeter, which provides an empirical formula to estimate SpO2 from videos. The respiration-dependent oscillation in CHbT was extracted from another FIR filter (low and high cut-off frequencies of 0.05 and 0.5 Hz, respectively) and used to calculate the RR. In vivo experiments with human volunteers while varying the fraction of inspired oxygen were performed to evaluate the comparability of the proposed method with commercially available devices. The Bland–Altman analysis showed that the mean bias for PR, RR, SpO2, and StO2 were -1.4 (bpm), -1.2(rpm), 0.5 (%), and -3.0 (%), respectively. The precisions for PR, RR, Sp O2, and StO2 were ±3.1 (bpm), ±3.5 (rpm), ±4.3 (%), and ±4.8 (%), respectively. The resulting precision and RMSE for StO2 were pretty close to the clinical accuracy requirement. The accuracy of the RR is considered a little less accurate than clinical requirements. This is the first demonstration of a low-cost RGB camera-based method for contactless simultaneous measurements of the heart rate, percutaneous arterial oxygen saturation, and tissue oxygen saturation in real-time.
Hemocompatibility of micropatterned biomaterial surfaces is dependent on topographical feature size
Authors: Fallon Meghan E. , Le Hillary H. , Bates Novella M. , Yao Yuan , Yim Evelyn K.F. , Hinds Monica T. , Anderson Deirdre E.J. 
Published: September 2022

Small-diameter synthetic vascular grafts that have improved hemocompatibility and patency remain an unmet clinical need due to thrombosis. A surface modification that has potential to attenuate these failure mechanisms while promoting an endothelial layer is the micropatterning of luminal surfaces. Anisotropic features have been shown to downregulate smooth muscle cell proliferation, direct endothelial migration, and attenuate platelet adhesion and activation. However, the effect of micropatterning feature size and orientation relative to whole blood flow has yet to be investigated within a systematic study. In this work, hemocompatibility of micropattern grating sizes of 2, 5, and 10 µm were investigated. The thrombogenicity of the micropattern surface modifications were characterized by quantifying FXIIa activity, fibrin formation, and static platelet adhesion in vitro. Additionally, dynamic platelet attachment and end-point fibrin formation were quantified using an established, flowing whole blood ex vivo non-human primate shunt model without antiplatelet or anticoagulant therapies. We observed a higher trend in platelet attachment and significantly increased fibrin formation for larger features. We then investigated the orientation of 2 µm gratings relative to whole blood flow and found no significant differences between the various orientations for platelet attachment, rate of linear platelet attachment, or end-point fibrin formation. MicroCT analysis of micropatterned grafts was utilized to quantify luminal patency. This work is a significant step in the development of novel synthetic biomaterials with improved understanding of hemocompatibility for use in cardiovascular applications.
Effect of innovative vs. usual care physical therapy in subacute rehabilitation after stroke. A multicenter randomized controlled trial
Authors: Sivertsen Marianne , Arntzen Ellen Christin , Alstadhaug Karl Bjørnar , Normann Britt 
Published: September 2022

BackgroundResearch on stroke rehabilitation often addresses common difficulties such as gait, balance or physical activity separately, a fragmentation contrasting the complexity in clinical practice. Interventions aiming for recovery are needed. The purpose of this study was to investigate effects of a comprehensive low-cost physical therapy intervention, I-CoreDIST, vs. usual care on postural control, balance, physical activity, gait and health related quality of life during the first 12 weeks post-stroke.MethodsThis prospective, assessor-masked randomized controlled trial included 60 participants from two stroke units in Norway. Participants, who were randomized to I-CoreDIST (n = 29) or usual care physical therapy (n = 31), received 5 sessions/week when in-patients or 3 sessions/week as out-patients. Primary outcomes were the Trunk Impairment Scale-modified Norwegian version (TISmodNV) and activity monitoring (ActiGraphsWgt3X-BT). Secondary outcomes were the Postural Assessment Scale for Stroke, MiniBesTEST, 10-meter walk test, 2-minute walk test, force-platform measurements and EQ5D-3L. Stroke specific quality of life scale was administered at 12 weeks. Linear regression and non-parametric tests were used for statistical analysis.ResultsFive participants were excluded and seven lost to follow-up, leaving 48 participants in the intention-to-treat analysis. There were no significant between-group effects for primary outcomes: TIS-modNV (p = 0,857); daily average minutes of sedative (p = 0.662), light (p = 0.544) or moderate activity (p = 0.239) and steps (p = 0.288), or secondary outcomes at 12 weeks except for significant improvements on EQ5D-3L in the usual care group. Within-group changes were significant for all outcomes in both groups except for activity levels that were low, EQ5D-3L favoring the usual care group, and force-platform data favoring the intervention group.ConclusionsPhysical therapy treatment with I-CoreDIST improved postural control, balance, physical activity and gait during the first 12 weeks after a stroke but is not superior to usual care.
Bioactivity of Ethanolic Extracts of Dipteryx punctata on Colletotrichum musae
Authors: Sousa Bruna Cristine Martins de , Gomes Daniel do Amaral , Vieira Thiago Almeida , Lustosa Denise Castro 
Published: September 2022

Bioactivity with antifungal properties has already been reported for some species of the genus Dipteryx. However, little is known about Dipteryx punctata. We evaluated the antifungal activity, in vitro and in vivo, of extracts of leaves, branches and fruits of D. punctata on Colletotrichum musae, the causal agent of anthracnose in bananas. The extracts and the coumarin standard were tested in vitro, at concentrations of 10%, 20%, 30%, 40%, and 50% (w/v), added in potato-dextrose-agar (PDA) medium. The experimental design was completely randomized, factorial design, with four replications. The average diameter of the fungal colonies was evaluated daily for eight days, and at the end, the percentage of inhibition and growth rates were calculated. For in vivo tests, the products were tested at concentrations of 40% and 50%, in preventive and curative applications. In these tests, three medium disks (5 mm) containing phytopathogen structures were deposited at opposite points of the fruits, and remained in a humid chamber for 48 h. Anthracnose lesions were measured at an interval of two days, up to eight days after fungus inoculation. In the in vitro essay, the extracts of the branches and residues of the fruits of D. punctata and the coumarin pattern caused the biggest reductions in the average diameter of the colonies of the phytopathogen. D. punctata and coumarin extracts were promising in terms of in vivo antifungal activity, especially in preventive applications, being an important source of investigation for the formulation of natural products as sustainable phytosanitary measures.
Consecutive Application Effects of Washed Rice Water on Plant Growth, Soil Chemical Properties, Nutrient Leaching, and Soil Bacterial Population on Three Different Soil Textures over Three Planting Cycles
Authors: Nabayi Abba , Teh Christopher Boon Sung , Tan Ali Kee Zuan , Tan Ngai Paing 
Published: September 2022

The benefits of washed rice water (WRW) as a plant fertilizer, particularly over a consecutive application period, are not well studied. An experiment was therefore carried out to determine: the continuous effects of applying unfermented (F0) and 3-day fermented (F3) WRW on the: (1) soil chemical properties, soil bacterial count, and the growth and plant nutrient content of a test crop, choy sum (Brassica chinensis var. parachinensis), grown on three contrasting soil textures (sandy clay loam, clay, and silt loam); (2) nutrient leaching losses from these three soils due to the continuous application of WRW; (3) crops’ improvement in water use, if any, in terms of its water productivity (WP) and water use efficiency (WUE); and (4) the relationship between soil bacterial count and plant growth parameters. The effects of F0 and F3 were compared with conventional NPK fertilizer and a control (only tap water; CON). Two factors, treatments and soil types, were used factorially in a randomized complete block design for three consecutive planting cycles. Results showed that NPK and F3 produced a significantly (p < 0.01) higher plant growth in terms of fresh and dry leaf weights and total leaf area by 5 to 61%, compared to that obtained in the other treatments. Furthermore, plants receiving either NPK or F3 had a significantly higher plant nutrient content (P, K, Ca, Mg, and Cu) in the third planting cycle. Clay soil treated with F3, NPK, and F0 had significantly higher NH4+, P, Ca, Mg, Zn, and B, by 19 to 152% relative to the other soils, irrespective of treatments. Soil nutrient leaching losses of P, K, Ca, Mg, Cu, Zn, and B decreased with successive planting cycles for all treatments. However, soils treated with either F3 or F0 experienced higher leaching of NH4+ and NO3− by 37 to 259% and 13 to 34%, respectively, relative to the NPK and CON. Plants treated with either NPK or F3 also had higher WP by 21 to 42% than the other treatments. For all the treatments, plants’ WUE increased with successive planting cycles; however, there was no significant difference between the treatments. F3 stimulated a significantly higher growth and yield of choy sum due to its nutrient and bacterial contents, and the continuous increase in plant growth with successive planting cycles indicated the carryover effects of the treatments, particularly by F3.
Healthy-like CD4+ Regulatory and CD4+ Conventional T-Cell Receptor Repertoires Predict Protection from GVHD Following Donor Lymphocyte Infusion
Authors: Schneider Jessica , Kuhlmann Leonie , Xiao Yankai , Raha Solaiman , Bernhardt Günter , Stadler Michael , Thol Felicitas , Heuser Michael , Eder Matthias , Ganser Arnold , Ravens Sarina , Förster Reinhold , Prinz Immo , Koenecke Christian , Schultze-Florey Christian R. 
Published: September 2022

Donor lymphocyte infusion (DLI) can (re-)induce durable remission in relapsing patients after allogeneic hematopoietic stem-cell transplantation (alloHSCT). However, DLI harbors the risk of increased non-relapse mortality due to the co-occurrence of graft-versus-host disease (GVHD). GVHD onset may be caused or accompanied by changes in the clonal T-cell receptor (TCR) repertoire. To investigate this, we analyzed T cells in a cohort of 21 patients receiving DLI after alloHSCT. We performed deep T-cell receptor β (TRB) sequencing of sorted CD4+CD25+CD127low regulatory T cells (Treg cells) and CD4+ conventional T cells (Tcon cells) in order to track longitudinal changes in the TCR repertoire. GVHD following DLI was associated with less diverse but clonally expanded CD4+CD25+CD127low Treg and CD4+ Tcon TCR repertoires, while patients without GVHD exhibited healthy-like repertoire properties. Moreover, the diversification of the repertoires upon GVHD treatment was linked to steroid-sensitive GVHD, whereas decreased diversity was observed in steroid-refractory GVHD. Finally, the unbiased sample analysis revealed that the healthy-like attributes of the CD4+CD25+CD127low Treg TCR repertoire were associated with reduced GVHD incidence. In conclusion, CD4+CD25+CD127low Treg and CD4+ Tcon TRB repertoire dynamics may provide a helpful real-time tool to improve the diagnosis and monitoring of treatment in GVHD following DLI.
THE MOBILE APPLICATION“HANDBOOK OF THE GSTOU APPLICANT» DEVELOPMENT
Authors: Алисултанова Э. Д. , Исаева М. З. , Пашаев М. Я. , Асхабов Х. Х. 
Published: September 2022

В данной статье рассматривается возможность и эффективность внедрения и эксплуатации мобильного приложения в инфраструктуру информационных технологий ГГНТУ. Дается обзор существующих решений, который определяет три основных способа разработки кроссплатформенных приложений: нативная разработка (в зависимости от конкретной мобильной платформы), HTML разработка и гибридное решение, комбинирующее оба подхода. В статье выяснены плюсы и минусы такого подхода, а также описываются характерные особенности Мобильных приложений.
This article changes the possibility and efficiency of the introduction and use of mobile applications in the information technology infrastructure of universities. The idea that it is necessary to implement a technological architecture for the development of native applications with a dynamic structure and content is substantiated. A comparison is given, an overview of existing solutions, which defines three main ways to develop cross-platform applications: native development (depending on the specific mobile platform), HTML development and a hybrid solution that combines both approaches. The analysis shows that native applications are superior to HTML5 and hybrid types of development, however, all cross-platform analogues of this type provide for the direct development of a mobile application, that is, writing program code. The article clarifies the pros and cons of this approach, and also describes the characteristic features of Mobile Applications.
EVOLUTION OF THE SCIENTIFIC RATIONALITY PROBLEM: A SOLUTION IN THE PHILOSOPHY OF EVOLUTIONISM
Authors: Яковлева Е. В. 
Published: September 2022

В статье произведен анализ общих проблем науки, показывающий существование ряда трудностей, связанных с невозможностью исчерпывающего изучения развития науки и критериев научности с позиций классической рацонально-логической методологии. Представляет интерес рассмотрение истории философии науки и ее эволюции в рамках проблемы научной рациональности. В свете этого на первый план выходит первоначальное изучение исходного понимания науки в идеальном ключе, что отражает парадигму восприятия философско-научной проблематики.
The article analyzes the general problems of science, showing the existence of a number of difficulties associated with the impossibility of an exhaustive study of the development of science and the criteria of science from the standpoint of classical rational-logical methodology. It is of interest to consider the history of the philosophy of science and its evolution within the framework of the problem of scientific rationality. In light of this, the initial study of the original understanding of science in an ideal way comes to the fore, which reflects the paradigm of perception of philosophical and scientific issues.
Analysis of Evaluative Questions in Eighth Grade Mathematics Textbook according to Bloom's Cognitive Domain Levels
Authors: Alqudah Muhannad Farhan Ahmed 
Published: September 2022

Objectives: The study aims to analyze evaluative questions included in eighth grade mathematics textbook in Jordan.
Methods: The researcher used a descriptive and analytical approach represented in content analysis. Evaluation items were built based on Bloom’s cognitive levels.
Results: The results show that the rates of availability of Bloom's cognitive levels in the eighth grade book were as follows: (30.74%) for the level of recall, (38.97%) for the level of comprehension, (11.93%) for the level of application, (11.84%) for the level of analysis, (1.18%) for the synthesis level, and (5.33%) for the evaluation level. The percentage of evaluative questions that measure the lower levels is (69.71%), and the percentage of questions that measure the intermediate levels is (11.93%), while the percentage of questions that measure the higher levels is (18.36%).
Conclusions: Based on the results above, the study recommends adding more evaluative questions that measure the levels of application, analysis, synthesis and evaluation to textbooks.
Effects of Difference in Augmented Reality Patterns on the Levels of Bloom's Pyramid and Reflective Thinking among Graduate Students at Taibah University
Authors: Al Shareef Bassem bin Nayef 
Published: September 2022

Objectives: The study aims to measure the effects of the difference in the augmented reality pattern on the levels of the Bloom pyramid and contemplative thinking among graduate students specializing in educational technology.
Methods: A quasi-experimental method was employed. Data was collected through two instruments: the first is a scale of contemplative thinking, while the second is a cognitive test of the levels of Bloom's pyramid. These were applied to a sample consisting of (33) students registered in the Educational Technology Assistance Course in the MA of Education Technology program at Taibah University. They were divided into two groups in a random way. The first group consisted of (17) students and studied the course via mobile augmented reality. The second group consisted of (16) students and studied the course via fixed augmented reality.
Results: The results show that there were statistically significant differences in arithmetic means and standard deviations between groups on the scale of contemplative thinking in favor of the augmented reality method. The results also show statistically significant differences in arithmetic means and standard deviations between groups on cognitive testing as a whole and the six levels of Bloom's pyramid in favor of augmented reality method.
Conclusions: The researchers recommend that educational institutions should produce programs that rely on augmented reality for all levels and educational disciplines. Additionally, they recommend paying attention to many elements that work on patterns of augmented reality and develop and strengthen them, such as visual culture and creative thinking.
Extent of Using Performance Skills for E-Learning by Faculty at Yarmouk University during the Coronavirus Pandemic
Authors: Alshbool Asmaa Khalifa Hamed , Fawares Haifa Fayyad Warrad 
Published: September 2022

Objectives: The purpose of this research is to evaluate the performance of faculty members at School of Sharia at Yarmouk University who had to resort to distance education during COVID-19 pandemic, specifically the problems they experienced and the strategies they used to cope with these problems.
Methods: The research followed a descriptive-analytical approach. A questionnaire consisting of (38) items was prepared and distributed to the study sample, which contained (48) faculty members.
Results: The results of the study reveal that the degree to which faculty members at School of Sharia at Yarmouk University exhibit ability to perform distance education was high. The arithmetic means of the research domains of the scale came out in the following order; the highest mean was for the domain of “electronic communication skills”, followed by the domain of "skills for using educational platforms". Then came the field of "internet use skills", followed by the field of "e-curriculum design skills".
Conclusion: The research made several recommendations, most notably holding training courses for faculty members to master e-learning skills.
The Values Included in the Textbooks of Social Studies for Upper Elementary Stage in Palestine
Authors: Abu Ghazaleh Aseel Hayhtam , Khweis Fatmah Iyad , Abu Dahouk Khawla Mahmoud , Ramahi Refa Jamal 
Published: September 2022

Objectives: This study aims to identify the values in the social studies textbooks for the upper elementary stage in Palestine.
Methods: The study relied on a descriptive analytical approach. The study sample consisted of all pages of social studies textbooks for the upper elementary stage (6-8) for the second semester, which include a set of units and lessons except for the introduction, references and questions. The sample was chosen in an intentional way. A list that includes the most important dimensions of values, sub-values, and the content analysis was used.
Results: The results of the study show that national values obtained the highest percentages among the values in the three grades. The scientific values in the sixth and seventh grades were the lowest. The general level of the values included in the curriculum of social studies for the higher elementary school grades was acceptable.
Conclusions: The study recommends confirming the level of integration among textbooks of social studies and enhancing educational values in the textbooks.
Self-Worth Level among Students of Practical Courses at School of Physical Education at Yarmouk University
Authors: Tilfah Yaser Mohamad , Melhem Mohammad Amein , Bani Hani Anan Hussein 
Published: September 2022

Objectives: The current study aims to identify the level of self-worth among students of practical courses at School of Physical Education at Yarmouk University.
Methods: The study relies on a descriptive design. The sample of the study consisted of (183) students (89 males and 94 females) who are registered in the second semester of the academic year 2019/2020 at Yarmouk Universisty. The sample was selected using a stratified random sampling method. To achieve the objectives of the study, the Self-Worth Scale developed by Krocker, Luttanen and Cooper (2003) was used.
Results: The results of the study show that the level of self-worth among students of practical courses at School of Physical Education at Yarmouk University was high. Moreover, there were no statistically significant differences in the level of self-worth due to gender, income level or academic achievement.
Conclusions: Based on the results above, the researchers recommend developing training programs to employ family support, competition, and academic competence in order to raise self-worth levels.