bluuebunny/crossref_metadata_2025_split huggingface dataset:
Choroidal Changes in Carotid Stenosis Patients After Stenting Detected by
Swept-source Optical Coherence Tomography Angiography
Authors: Hu Fayun , Wu Bo , Wan Jincheng , Kwapong William Robert , Tao. Wendan , Lu Kun , Jiang Shuai , Zheng Hongbo 
Published: April 2022

Background:
Carotid artery stenosis (CAS) patients show reduced blood flow in the ophthalmic
artery. This study aimed to assess the changes in the choriocapillaris and choroidal thickness
in patients with unilateral carotid artery stenosis after carotid stenting using swept-source optical
coherence tomography (SS-OCT)/swept-source optical coherence tomography angiography (SSOCTA).

Methods:
Fifty-three mild to moderate CAS patients and 40 controls were enrolled in this study. All
participants underwent digital subtraction angiography (DSA) and SS-OCT/SS-OCTAA imaging
before and 4 days after carotid artery stenting. SS-OCTA was used to image and measure the perfusion
of the choriocapillaris (mm2), while SS-OCT was used to image and measure the choroidal
thickness (μm). The stenosed side was described as the ipsilateral eye, while the other side was the
contralateral eye.

Results:
Choroidal thickness was significantly thinner (P = 0.024) in CAS when compared with
controls. Ipsilateral eyes of CAS patients showed significantly thinner (P = 0.008) choroidal thickness
when compared with contralateral eyes. Ipsilateral eyes of CAS patients showed thicker (P =
0.027) choroidal thickness after carotid artery stenting, while contralateral eyes showed thinner choroidal
thickness (P = 0.039).

Conclutions:
Our report suggests that in vivo quantification of the choroid with the SS-OCT/SSOCTA
may allow monitoring of CAS and enable the assessment of purported treatments.
Mechanisms of Compound Sophora flavescens (Kushen) Decoction for the
Treatment of Ulcerative Colitis based on Network Pharmacology and Molecular
Docking Technology
Authors: Li Xiaoyan , Xie Jingwen , Peng Zijing , Zheng Zhuoling , Gao Min , Qin Li , Xiong Lixiong 
Published: April 2022

Background:
The compound Sophora flavescenes (Kushen) decoction was found to reduce the inflammatory symptom of Ulcerative Colitis (UC). However, there exists a very limited understanding of the molecular pharmacological mechanisms.

Objective:
This study aimed to explore the mechanism of compound Sophora flavescens (Kushen) decoction in treating ulcerative colitis from the perspective of network pharmacology.

Methods:
Active components and potential targets of compound Sophora flavescens (Kushen) de-coction were obtained through the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP) database. GeneCards and other databases were used to predict and screen ulcerative colitis-related genes. Cytoscape software was applied to construct the “drug-active component-disease-target” network. GO function and KEGG pathway enrichment analyses revealed the potential pathway of the compound Sophora flavescenes (Kushen) decoction for UC.

Results:
After the screening, a total of 124 active ingredients and 163 potential therapeutic targets for UC were obtained from the compound Sophora flavescens (Kushen) decoction. Protein inter-action network analysis showed that 15 key targets could be identified for the possible treatment of UC. GO and KEGG analyses showed that the active ingredients in the compound Sophora fla-vescens (Kushen) decoction were mainly enriched in 2556 biological processes and 172 signaling pathways.

Conclusion:
The study showed that the compound Sophora flavescens (Kushen) decoction has therapeutic effects on UC through multi-component, multi-target, and multi-pathway.
Grape Phytochemicals and Vitamin D in the Alleviation of Lung Disorders
Authors: Santa Kazuki 
Published: April 2022

Background:
Typical lung diseases are pneumonia, asthma, sleep apnea syndrome (SA),
interstitial pneumonia (IP), lung cancer, and chronic obstructive pulmonary disease (COPD). Coronavirus
disease 2019 (COVID-19) is a type of viral pneumonia. Many researchers have reported that phytochemicals
(chemical compounds produced by plants) and vitamin D are useful in stimulating our
immunity. This review discusses the alleviation of lung diseases by grape phytochemicals and vitamin
D.

Discussion:
Pneumonia is an acute inflammation caused by the infection of pathogens; the worst case
is a fatal cytokine storm in the lung. In asthma, allergens, tobacco smoke, or air pollution may cause
seizures. Lung diseases caused by lung fibrosis may manifest chronic inflammation, progress into alveolar
fibrosis, and cause respiratory malfunction. SA is a lifestyle disease related to obesity and metabolic
syndrome. To alleviate these symptoms, changing the eating habit is one of the strategies. Improvement
in the daily lifestyle reduces the risk of lung cancer. Self-management, including nutritional
management and exercise, is very important for COPD patients in addition to pharmacotherapy.

Conclusion:
The intake of grape phytochemicals and vitamin D prevents the progress of lung diseases.
Both phytochemicals and vitamin D prevent the production of proinflammatory cytokine, TNF-α, that
is responsible for inflammation and lung diseases. Daily intake of grape phytochemicals is important.
The optimum vitamin D level in serum is > 30 ng/mL. For the prevention of lung diseases, upregulating
immunity and maintaining good gut microbiota are important because gut microbiota change
depending on what we eat.
A Mobile-based Virtual Reality Speech Rehabilitation App for Patients With Aphasia After Stroke: Development and Pilot Usability Study
Authors: Bu Xiaofan , Ng Peter HF , Tong Ying , Chen Peter Q , Fan Rongrong , Tang Qingping , Cheng Qinqin , Li Shuangshuang , Cheng Andy SK , Liu Xiangyu 
Published: April 2022

Background
Stroke has the highest disability-adjusted life-years lost in any disease, and approximately one-third of the patients get aphasia. Computers and tablets are innovative and aid in intensive treatments in speech rehabilitation for patients with aphasia. However, mechanical training limits the help to patients.

Objective
This study aims to provide a framework for an integrated virtual reality (VR) app to provide speech rehabilitation for patients with aphasia.

Methods
The content was generated through an in-depth literature review and discussion with experienced rehabilitation physicians and occupational therapists. We then conducted a 2-round Delphi study with 15 experts from hospitals and universities to rate the content using a 5-point Likert scale. The app was developed by an interdisciplinary team involving VR, medical science of rehabilitation, and therapeutic rehabilitation. Pilot usability testing of this novel app was conducted among 5 patients with aphasia, 5 healthy volunteers, 5 medical staff, and 2 VR experts.

Results
We designed 4 modules of speech rehabilitation: oral expression, auditory comprehension, cognition, and comprehensive application. Our VR-based interactive and intelligent app was developed to provide an alternative option for patients with aphasia. Pilot usability testing revealed user satisfaction with the app.

Conclusions
This study designed and tested a novel VR-based app for speech rehabilitation specifically adapted to patients with aphasia. This will guide other studies to develop a similar program or intelligent system in a clinical setting.
EFFECT OF ROA, NPM, CR, EPS ON STOCK PRICES IN CONSUMER GOODS COMPANIES
Authors: Novita Herlina , Pratama Surbakti Michael , Yanti Manalu Fitri , Yanti Silalahi Kristina Eva , Hezellyta Bukit Rany 
Published: April 2022

This study aims to determine the effect of ROA, NPM, CR, and EPS simultaneously and partially on stock prices in consumer goods companies listed on the IDX for the period 2017 – 2020. This study uses a population of 53 consumer goods companies listed on the IDX for the 2017period – 2020. The method used in this study is a quantitative method. The data used are secondary data registered through the official website www.idx.co.id and www.idn.financials.com. In this study, the sample was taken using purposive sampling technique. This research was tested using the classical assumption test. The data investigation method used was the multiple linear regression method. The results showed that partially ROA, CR, and EPS had a significant effect on stock prices partially and NPM had a positive and significant effect on stock prices. IDX for the period 2017 – 2020.
Adaptasi Kebiasaan Baru pada Masa Pandemi Covid-19: Studi Cross-Sectional di Provinsi DKI Jakarta
Authors: Hanifah Wardah , Oktaviani Anissa Dwi , Syadidurrahmah Fidah , Kundari Nurul Fadhillah , Putri Rizky Muharany , Fitriani Tri Aulia , Nisa Hoirun 
Published: April 2022

Adapting New Habits (ANH) is a new way of life to maintain productivity during the COVID-19 pandemic by implementing COVID-19 prevention behaviors. The ANH implemented in stages according to specific regional conditions. This study aims to determine the factors influencing the people of DKI Jakarta in implementing ANH readiness behavior. This cross-sectional study was conducted from September-October 2020 in Jakarta by a voluntary sampling technique. The questionnaire was distributed by online form via social media and achieved total 424 respondents. The proportion for respondents with good ANH readiness behavior was 57.10%. The multivariate analysis showed gender (OR = 2.29; 95% CI = 1.38-3.80), attitudes towards ANH (OR = 4.41; 95% CI = 2.78-6.98), infrastructure for IMR (OR = 1.97; 95% CI = 1.27-3.10), the frequency of seeking ANH information (OR = 1.94; 95% CI = 1.24-3.03) was significantly related to ANH behavior (P <0.05). Gender, attitudes towards ANH, infrastructure for ANH, and frequency of seeking ANH information had contribution in encouraging ANH readiness behavior among people in Jakarta. The Provincial Government and Health Office of Jakarta need to strengthen optimum health promotion and to design strategies to influence people's attitudes towards ANH.
Abstrak
Adaptasi Kebiasaan Baru (AKB) merupakan tindakan menerapkan tatanan hidup baru guna menjaga produktivitas selama masa pandemi COVID-19 dengan menerapkan perilaku pencegahan penularan COVID-19. Pemberlakuan AKB dilakukan bertahap sesuai kondisi wilayah. Penelitian ini bertujuan untuk menganalisis perilaku AKB masyarakat DKI Jakarta dan faktor yang mempengaruhinya. Penelitian potong lintang ini dilakukan pada bulan September—Oktober 2020 di DKI Jakarta dengan teknik voluntary sampling. Kuesioner disebarkan secara online melalui media sosial dan sebanyak 424 responden berpartisipasi. Proporsi responden dengan perilaku AKB yang baik adalah 57,10%. Hasil analisis multivariat menunjukkan gender (OR= 2,29; CI 95%= 1,38—3,80), sikap terhadap AKB (OR= 4,41; CI 95%= 2,78—6,98), sarana prasarana untuk AKB (OR= 1,97; CI 95%= 1,27—3,10), frekuensi pencarian informasi AKB (OR= 1,94; CI 95%= 1,24—3,03) berhubungan signifikan dengan perilaku AKB (P<0,05). Gender, sikap terhadap AKB, sarana prasarana untuk AKB, dan frekuensi mencari informasi AKB berperan untuk mendorong perilaku AKB pada masyarakat DKI Jakarta. Pemerintah Provinsi dan Dinas Kesehatan DKI Jakarta disarankan untuk memperkuat promosi kesehatan secara masif dan merancang strategi guna mempengaruhi sikap masyarakat terhadap AKB.
Religiositas Dan Kelengkapan Imunisasi Dasar Pada Anak
Authors: Kusnali Asep , Dartanto Teguh 
Published: April 2022

Information on the absence of basic immunization due to religious reasons and the general overview of immunization coverage among religious believers in Indonesia is still limited. This study aims to examine the relationship between parental religiosity and basic immunization status on children because there are still many children who are not fully immunized in Indonesia. This study used cross-sectional data of the Indonesia Family Life Survey (IFLS) 2007 and 2014 with the unit of analysis for families having children aged 1-5 years. Our estimations using ordered logistic regression confirm that there is a relationship between religiosity on the parents' decision to perform basic immunization on their children. The differences in religiosity patterns in 2007 and 2014 illustrate changes in individual religious behavior towards the basic immunization program. These changes occur through religious social support.
Abstrak
Informasi tidak dilakukannya imunisasi dasar karena alasan agama masih terbatas dan gambaran cakupan imunisasi di antara pemeluk agama di Indonesia secara aktual belum dapat diketahui. Penelitian ini bertujuan untuk menjelaskan hubungan antara religiositas orang tua dengan status imunisasi dasar pada anak dikarenakan masih banyaknya anak yang tidak diberikan imunisasi secara lengkap di Indonesia. Penelitian ini menggunakan desain cross sectional dengan sumber data Indonesia Family Life Survey (IFLS) Tahun 2007 dan 2014 dengan unit analisis keluarga yang memiliki anak usia 1-5 tahun dan dianalisis menggunakan regresi ordered logistic. Hasil analisis menunjukkan adanya hubungan antara religiositas terhadap keputusan orang tua untuk melakukan imunisasi dasar pada anaknya. Perbedaan pola religiositas tahun 2007 dan 2014 menggambarkan adanya perubahan perilaku beragama individu terhadap program imunisasi dasar. Perubahan tersebut dapat terjadi melalui dukungan sosial keagamaan.
Kepemilikan Asuransi Kesehatan Dan Hubungannya Dengan Persalinan Pada Dukun Bayi
Authors: Pristya Terry Y.R. , Nurcandra Fajaria , Fitri Azizah Musliha 
Published: April 2022

Delivery by traditional birth attendants (TBAs) has become a culture in several regions in Indonesia. The absence of health insurance ownership and lack of knowledge have supported the decision to choose TBA by the expectant mothers. This study aimed to determine the relationship between health insurance ownership with delivery by TBA. This research was a cross-sectional study with 120 samples of women aged 15-49 years who had ever given birth in the last five years and lived in Sangiangtanjung Village, Lebak, Banten. Multivariate logistic regression analysis was used in this study consist of health insurance ownership with delivery by TBAs controlled by age, education, socioeconomic, knowledge, antenatal care provider, frequency of antenatal care, and danger of pregnancy. The results showed that women who did not have health insurance were 3.20 times higher (95%CI= 1.10-9.30) for choosing delivery by TBAs compared to women who had health insurance after being controlled by knowledge. This study concluded that there was a significant relationship between health insurance ownership with delivery by TBAs. This study suggests that it is needed to conduct maternity care about health insurance ownership and positive health-seeking behavior, and the system of integrating TBAs with skilled birth attendants especially midwives in which TBAs as birth companions.
Abstrak
Persalinan oleh dukun bayi sudah menjadi budaya di beberapa daerah di Indonesia. Tidak adanya jaminan kesehatan dan pengetahuan menjadi pendorong dalam pemilihan dukun sebagai penolong persalinan. Penelitian bertujuan mengetahui hubungan antara kepemilikan asuransi kesehatan dengan persalinan oleh dukun bayi. Penelitian kuantitatif ini menggunakan desain potong lintang dengan 120 sampel. Sampel merupakan wanita berusia 15-49 tahun yang melahirkan dalam lima tahun terakhir dan tinggal di Desa Sangiangtanjung, Lebak, Banten. Analisis multivariat regresi logistik digunakan dalam penelitian ini terdiri dari kepemilikan asuransi kesehatan dengan persalinan oleh dukun bayi dan dikontrol oleh usia ibu, pendidikan ibu, sosial ekonomi, pengetahuan, tenaga pemeriksa kehamilan, frekuensi pemeriksaan kehamilan, dan bahaya kehamilan. Hasil penelitian menunjukkan bahwa ibu yang tidak memiliki asuransi kesehatan 3,20 kali lebih tinggi (95% CI = 1,10-9,30) untuk melakukan persalinan oleh dukun bayi dibandingkan dengan ibu yang memiliki asuransi kesehatan setelah dikontrol oleh pengetahuan. Penelitian ini menyimpulkan bahwa terdappat hubungan antara kepemilikan asuransi kesehatan dengan persalinan oleh dukun bayi. Diperlukan asuhan maternitas tentang kepemilikan asuransi dan perilaku pencarian kesehatan yang positif, serta pengintegrasian dukun bayi dengan tenaga kesehatan terutama bidan di mana dukun bayi perlu ditetapkan kembali perannya sebagai pendamping kelahiran.
Nilai Budaya Jawa Dalam Pengendalian Malaria Untuk Mencapai Eliminasi Malaria Di Kawasan Bukit Menoreh
Authors: Isnani Tri , Ikawati Bina , Prastawa Asnan , Sholichah Zumrotus 
Published: April 2022

Bukit Menoreh is a border area of three regencies and two provinces which have malaria problems. The target to achieve and maintain the predicate as being free or has eliminated malaria was carried out byvarious control methods, either as government programs or community participations. The area itself is a Javanese cultural area in which its values are stronglyheld. This affects existing malaria control efforts. The research was conducted with a qualitative approach, held in three districts in Bukit Menoreh, each with 2 villages. The data was obtained through observations, indepth interview, and focus group discussions (FGD) with 3 groups in each village. The results showed that from the various control efforts carried out there was a culture of ‘isin’ (shame), ‘pekewuh’ (feeling of reluctant), and the influence of community leaders, especially in ‘gotong royong’ or community service activities in environmental cleanliness, health educations, and migration surveillance. The conclusion of this study is that some of these values are supportive, and some are hindering the effort to control malaria. Therefore, a special approach is needed with attention to culture. Intervention to control malaria should pay local wisdom and culture so it can be accepted and implemented.
Abstrak

Bukit Menoreh adalah daerah perbatasan tiga kabupaten dari dua provinsi yang merupakan daerah dengan masalah malaria. Target mencapai dan mempertahankan predikat bebas atau eliminasi malaria dilakukan dengan berbagai cara pengendalian, baik program dari pemerintah maupun peran serta masyarakat. Wilayah ini merupakan wilayah budaya Jawa yang di dalamnya terdapat nilai-nilai budaya yang masih kuat dipegang. Hal ini berpengaruh terhadap usaha pengendalian malaria yang ada. Penelitian dilakukan dengan pendekatan kualitatif, di tiga kabupaten di Bukit Menoreh masing-masing diambil dua desa. Data diperoleh melalui observasi, wawancara mendalam, dan diskusi kelompok terarah (DKT) terhadap tiga kelompok di tiap desa. Hasil penelitian menunjukkan dari berbagai usaha pengendalian malaria terdapat budaya rasa isin (malu), rasa ewuh (sungkan), dan panut (patuh) terhadap pengaruh tokoh dalam masyarakat terutama dalam kegiatan kerja bakti atau gotong royong kebersihan lingkungan, sosialisasi, dan surveilans migrasi. Penelitian ini menyimpulkan bahwa nilai tersebut ada yang mendukung dan ada yang menghambat usaha pengendalian malaria sehingga diperlukan pendekatan khusus dengan memperhatikan budaya. Kebijakan pengendalian malaria sebaiknya memperhatikan budaya lokal sehingga bisa menggunakan budaya lokal dan bisa diterima dan diterapkan.
Faktor-Faktor Penyebab Pernikahan Dini di Beberapa Etnis Indonesia
Authors: Handayani Sri , Nuraini Syarifah , Agustiya Rozana Ika 
Published: April 2022

Early marriage is still a severe problem in Indonesia. One out of nine women in Indonesia is married before eighteen. It occurs almost in all over provinces in Indonesia. There are 23 provinces where the prevalence of early marriage is higher than the national data. This article aims to determine factors that cause early marriage in several ethnic groups in Indonesia. This study reviews the Ethnographic Health Research book series in the Lampung, Sasak and Bugis ethnic groups. Pierre Bourdieu’s theory was used to analyze the phenomenon of early marriage. Bourdieu divides this theory of social practice into three interrelated parts: habitus, arena, and capital. The existence of customary rules, patriarchal systems, modernization and applicable formal laws, namely marriage laws, affect the habitus of early marriage actors. Weak economic, cultural and social capital also encourages individuals to marry earlier. In conclusion, the relationship between habits, The involvement of the capital owned by adolescent or their families influences the decision to have an early marriage. The prevention of early marriage needs mutual interactions by both structural and cultural conditions of the community. The role of traditional and religious leaders also needs to be optimized in preventing early marriage. It is also necessary to strengthen the implementation of the law that regulates the minimum age for marriage.
Abstrak
Pernikahan dini masih menjadi masalah yang serius dihadapi oleh Indonesia. Satu dari sembilan perempuan di Indonesia menikah sebelum usia 18 tahun. Pernikahan dini hampir terjadi di seluruh wilayah Indonesia. Terdapat 23 provinsi dengan prevalensi pernikahan dini lebih tinggi dari angka nasional. Artikel ini bertujuan untuk mengetahui faktor-faktor penyebab pernikahan dini pada beberapa etnis di Indonesia. Kajian literatur dari buku seri Riset Etnografi Kesehatan pada etnis Lampung, Sasak dan Bugis dipilih menjadi metode pada artikel ini. Untuk menganalisis fenomena pernikahan dini digunakan teori praktik sosial oleh Pierre Bourdieu. Bourdieu membagi teori praktek sosial ini menjadi tiga bagian yang saling berkaitan, yaitu: habitus, arena dan modal. Adanya aturan adat, sistem patriarki, modernisasi dan hukum formal yang berlaku yaitu undang-undang perkawinan mempengaruhi habitus pelaku pernikahan dini. Lemahnya modal ekonomi, kultural dan sosial juga turut mendorong individu melakukan pernikahan dini. Kesimpulan dari analisis tersebut adalah relasi antara habitus, arena dengan melibatkan modal yang dimiliki oleh remaja atau keluarganya mempengaruhi keputusan untuk melakukan pernikahan dini. Upaya pencegahan pernikahan dini perlu dilakukan dengan memperhatikan kondisi struktur dan budaya masyarakat. Peran tokoh adat dan tokoh agama juga perlu dioptimalkan dalam mencegah pernikahan dini. Penguatan implementasi undang-undang yang mengatur batas minimum usia menikah juga perlu dilakukan.
The Inferiority Complex Constructed by the Dominant Power in Rhys’ Wide Sargasso Sea (1966): Postcolonial Analysis
Authors: Widyaningrum Indiwara Pandu 
Published: April 2022

This study focuses on the construction of identity shaped by the dominant class. Jean Rhys’ Wide Sargasso Sea portrays the complexity of identity in the figure of Creole woman, Antoinette, for belonging to neither the Jamaican society nor the European. Using interpretive qualitative approach as its method, this study applies the theory of power and knowledge to reveal the imbalance power relation between center and marginalized. The result of analysis shows that both Jamaican society and Rochester have the contribution in shaping the inferiority complex to Antoinette. The representation of madwoman in Antoinette implies the constructed truth framed by the dominant class. As a result of the inferiority complex, the dependency of the inferior on the superior grows which consolidates the domination of power. Under this situation, the dominant power legitimates their authority to represent others as well as to control the marginalized side. Thus, this study intends to raise the awareness of any kind of oppression which limits people to have a voice.