bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validation and Cultural Adaptation of an Arabic Version of Pediatric Eating Assessment Tool (Pedi-EAT-10Arabic)
Authors: Adel Sally M. , Gaafar Alaa H. , Fasseeh Nader , Abdou Rania M. , Hamouda Nesrine Hazem 
Published: January 2022

AbstractPediatric eating assessment tool (Pedi-EAT-10Arabic) is a validated and reliable caregiver administered outcome instrument designed for detection of children at high risk of penetration/aspiration. The objective of this study is to translate and validate the Arabic version of Pedi-EAT-10 and to correlate its results with pharyngeal residue and aspiration on fiber optic endoscopic examination of swallowing (FEES). A cross-sectional study including 202 children selected randomly from those attending the swallowing clinic in phoniatrics unit, Otorhinolaryngology department (ORL) at main university hospital between February 2019 and October 2020 complaining of dysphagia. For test–retest reliability, one hundred caregivers refilled the Pedi-EAT-10Arabic after a 2-week period following their first visit. Validity was established by comparing the scores of dysphagia patients to healthy controls. Internal consistency of Pedi-EAT-10Arabic was high (Cronbach's alpha 0.986). Intra class correlation showed excellent test–retest reliability (r = 0.968). The median Pedi-EAT 10Arabic score was significantly higher in dysphagia group compared to healthy controls. (Median 27 IQR 21–34 for cases compared to median zero IQR 0–2 points for healthy controls, P less than 0.001). A strong correlation was found between Pedi-EAT 10Arabic scores and PAS scores with Spearman's correlation coefficient r = 0.803 and P < 0.001. The ROC for evaluating the discriminatory capacity of Pedi-EAT 10 for aspiration showed an AUC of 0.92 (95% CI of 0.89 to 0.96). Conclusion: Pedi-EAT 10Arabic was found to be a valid and reliable screening tool for further instrumental assessment of risk of dysphagia in pediatric population.
Routine cancer treatments and their impact on physical function, symptoms of cancer-related fatigue, anxiety, and depression
Authors: Grusdat Niklas Paul , Stäuber Alexander , Tolkmitt Marion , Schnabel Jens , Schubotz Birgit , Wright Peter Richard , Schulz Henry 
Published: January 2022

AbstractBackground and purposeBreast cancer can be a major challenge for affected women. Knowledge of the physical function, symptoms of cancer-related fatigue, anxiety, and depression based on the cancer treatment may help to guide adequate support.MethodsFor this prospective observational study, we collected data from seventy-nine women with a mean age 54.6 ± 9.5 years prior to the onset of breast cancer treatment (T0) and after (T1/T2). Handgrip strength test (HGS), six-minute walk test (6MWT), the phase angle (PhA), the hospital anxiety and depression scale (HADS), and functional assessment of chronic illness therapy-fatigue (FACIT-F) were used to collect data from four treatment subgroups SC, surgery + chemotherapy; SCR, surgery + chemotherapy + radiation therapy; SR, surgery + radiation therapy; and S, surgery.ResultsA mixed ANOVA revealed a significant interaction between time and group for PhA,F = 8.55,p < 0.01; HGS,F = 3.59,p < 0.01; 6MWT,F = 4.47,p < 0.01; and FACIT-F,F = 2.77,p < 0.05 with most pronounced deterioration seen in group SCR (PhA 4.8°; HGS 27.5 kg, 6MWT 453.4 m, FACIT-F 33.8 points). HADS data displayed moderate anxiety and depression predominantly after treatment.ConclusionOur study showed that the extent of change in physical function, symptoms of fatigue, anxiety, and depression depends on the treatment conditions. The potentially higher risk of impaired function due to the prevalence of values below a critical threshold requires early initiated multidisciplinary support.
Deep learning and Internet of Things for tourist attraction recommendations in smart cities
Authors: Cepeda-Pacheco Juan Carlos , Domingo Mari Carmen 
Published: January 2022

AbstractWe propose a tourist attraction IoT-enabled deep learning-based recommendation system to enhance tourist experience in a smart city. Travelers will enter details about their travels (traveling alone or with a companion, type of companion such as partner or family with kids, traveling for business or leisure, etc.) as well as user side information (age of the traveler/s, hobbies, etc.) into the smart city app/website. Our proposed deep learning-based recommendation system will process this personal set of input features to recommend the tourist activities/attractions that best fit his/her profile. Furthermore, when the tourists are in the smart city, content-based information (already visited attractions) and context-related information (location, weather, time of day, etc.) are obtained in real time using IoT devices; this information will allow our proposed deep learning-based tourist attraction recommendation system to suggest additional activities and/or attractions in real time. Our proposed multi-label deep learning classifier outperforms other models (decision tree, extra tree, k-nearest neighbor and random forest) and can successfully recommend tourist attractions for the first case [(a) searching for and planning activities before traveling] with the loss, accuracy, precision, recall and F1-score of 0.5%, 99.7%, 99.9%, 99.9% and 99.8%, respectively. It can also successfully recommend tourist attractions for the second case [(b) looking for activities within the smart city] with the loss, accuracy, precision, recall and F1-score of 3.7%, 99.5%, 99.8%, 99.7% and 99.8%, respectively.
Data fusion and 3D visualization for optimized representation of neurovascular relationships in the posterior fossa
Authors: Hastreiter Peter , Bischoff Barbara , Fahlbusch Rudolf , Doerfler Arnd , Buchfelder Michael , Naraghi Ramin 
Published: January 2022

Abstract

Background
Reliable 3D visualization of neurovascular relationships in the posterior fossa at the surface of the brainstem is still critical due to artifacts of imaging. To assess neurovascular compression syndromes more reliably, a new approach of 3D visualization based on registration and fusion of high-resolution MR data is presented.

Methods
A total of 80 patients received MRI data with 3D-CISS and 3D-TOF at 3.0 Tesla. After registration and subsequent segmentation, the vascular information of the TOF data was fused into the CISS data. Two 3D visualizations were created for each patient, one before and one after fusion, which were verified with the intraoperative situation during microvascular decompression (MVD). The reproduction quality of vessels was evaluated with a rating system.

Results
In all cases, the presented approach compensated for typical limitations in the 3D visualization of neurovascular compression such as the partial or complete suppression of larger vessels, suppression of smaller vessels at the CSF margin, and artifacts from heart pulsation. In more than 95% of the cases of hemifacial spasm and glossopharyngeal neuralgia, accurate assessment of the compression was only possible after registration and fusion. In more than 50% of the cases with trigeminal neuralgia, the presented approach was crucial to finding the actually offending vessel.

Conclusions
3D visualization of fused image data allows for a more complete representation of the vessel-nerve situation. The results from this approach are reproducible and the assessment of neurovascular compression is safer. It is a powerful tool for planning MVD.
Prevalence of SARS-CoV-2 IgG antibodies among dental teams in Germany
Authors: Mksoud Maria , Ittermann Till , Holtfreter Birte , Söhnel Andreas , Söhnel Carmen , Welk Alexander , Ulm Lena , Becker Karsten , Hübner Nils-Olaf , Rau Andrea , Kindler Stefan , Kocher Thomas 
Published: January 2022

Abstract

Objectives
During the corona pandemic, dental practices temporarily closed their doors to patients except for emergency treatments. Due to the daily occupational exposure, the risk of SARS-CoV-2 transmission among dentists and their team is presumed to be higher than that in the general population. This study examined this issue among dental teams across Germany.

Materials and methods
In total, 2784 participants provided usable questionnaires and dry blood samples. Dry blood samples were used to detect IgG antibodies against SARS-CoV-2. The questionnaires were analyzed to investigate demographic data and working conditions during the pandemic. Multivariable logistic mixed-effects models were applied.

Results
We observed 146 participants with positive SARS-CoV-2 IgG antibodies (5.2%) and 30 subjects with a borderline finding (1.1%). Seventy-four out of the 146 participants with SARS-CoV-2 IgG antibodies did not report a positive SARS-CoV-2 PCR test (50.7%), while 27 participants without SARS-CoV-2 IgG antibodies reported a positive SARS-CoV-2 PCR test (1.1%). Combining the laboratory and self-reported information, the number of participants with a SARS-CoV-2 infection was 179 (6.5%). Though after adjustment for region, mixed-effects models indicated associations of use of rubber dams (OR 1.65; 95% CI: 1.01–2.72) and the number of protective measures (OR 1.16; 95% CI: 1.01–1.34) with increased risk for positive SARS-CoV-2 status, none of those variables was significantly associated with a SARS-CoV-2 status in fully adjusted models.

Conclusions
The risk of SARS-CoV-2 transmission was not higher among the dental team compared to the general population.
Clinical relevance.
Following hygienic regulations and infection control measures ensures the safety of the dental team and their patients.
Bullous Parametric Response Map for Functional Localization of COPD
Authors: Lor Kuo-Lung , Chang Yeun-Chung , Yu Chong-Jen , Wang Cheng-Yi , Chen Chung-Ming ,   On behalf of the TCORE consortium
Published: January 2022

AbstractAdvanced bronchoscopic lung volume reduction treatment (BLVR) is now a routine care option for treating patients with severe emphysema. Patterns of low attenuation clusters indicating emphysema and functional small airway disease (fSAD) on paired CT, which may provide additional insights to the target selection of the segmental or subsegmental lobe of the treatments, require further investigation. The low attenuation clusters (LACS) were segmented to identify the scalar and spatial distribution of the lung destructions, in terms of 10 fractions scales of low attenuation density (LAD) located in upper lobes and lower lobes. The LACs of functional small airway disease (fSAD) were delineated by applying the technique of parametric response map (PRM) on the co-registered CT image data. Both emphysematous LACs of inspiratory CT and fSAD LACs on expiratory CT were used to derive the coefficients of the predictive model for estimating the airflow limitation. The voxel-wise severity is then predicted using the regional LACs on the co-registered CT to indicate the functional localization, namely, the bullous parametric response map (BPRM). A total of 100 subjects, 88 patients with mild to very severe COPD and 12 control participants with normal lung functions (FEV1/FVC % > 70%), were evaluated. Pearson’s correlations between FEV1/FVC% and LAV%HU-950 of severe emphysema are − 0.55 comparing to − 0.67 and − 0.62 of LAV%HU-856 of air-trapping and LAV%fSAD respectively. Pearson’s correlation between FEV1/FVC% and FEV1/FVC% predicted by the proposed model using LAD% of HU-950 and fSAD on BPRM is 0.82 (p < 0.01). The result of the Bullous Parametric Response Map (BPRM) is capable of identifying the less functional area of the lung, where the BLVR treatment is aimed at removing from a hyperinflated area of emphysematous regions.
Does ( −)-epigallocatechin-3-gallate protect the neurotoxicity induced by bisphenol A in vivo?
Authors: El Tabaa Manar Mohammed , Sokkar Samia Salem , Ramdan Ehab Sayed , El Salam Inas Zakria Abd , Anis Anis 
Published: January 2022

AbstractBisphenol
A (BPA) is one of the chemicals that is firmly accompanied by hippocampal neuronal injury. As oxidative stress appears to be a major contributor to neurotoxicity induced by BPA, antioxidants with remarkable neuroprotective effects can play a valuable protective role. Around the world, ( −)-epigallocatechin-3-gallate (EGCG) was one of the most popular antioxidants that could exert a beneficial neuroprotective role. Here, we examined the potential efficiency of EGCG against neurotoxicity induced by BPA in the hippocampal CA3 region of the rat model. This study revealed that EGCG was unable to abrogate the significant decrease in circulating adiponectin level and hippocampal superoxide dismutase activity as well as an increase in hippocampal levels of nitric oxide and malondialdehyde. Notably, EGCG failed to antagonize the oxidative inhibitory effect of BPA on hippocampal neurotransmission and its associated cognitive deficits. In addition, the histopathological examination with immunohistochemical detection of caspase-3 and NF-kB/p65 emphasized that EGCG failed to protect hippocampal CA3 neurons from apoptotic and necrotic effects induced by BPA. Our study revealed that EGCG showed no protective role against the neurotoxic effect caused by BPA, which may be attributed to its failure to counteract the BPA-induced oxidative stress in vivo. The controversial effect is probably related to EGCG’s ability to impede BPA glucuronidation and thus, its detoxification. That inference requires further additional experimental and clinical studies.
Graphical abstract
8 Å structure of the outer rings of the Xenopus laevis nuclear pore complex obtained by cryo-EM and AI
Authors: Tai Linhua , Zhu Yun , Ren He , Huang Xiaojun , Zhang Chuanmao , Sun Fei 
Published: January 2022

AbstractThe nuclear pore complex (NPC), one of the largest protein complexes in eukaryotes, serves as a physical gate to regulate nucleocytoplasmic transport. Here, we determined the 8 Å resolution cryo-electron microscopic (cryo-EM) structure of the outer rings containing nuclear ring (NR) and cytoplasmic ring (CR) from the Xenopus laevis NPC, with local resolutions reaching 4.9 Å. With the aid of AlphaFold2, we managed to build a pseudoatomic model of the outer rings, including the Y complexes and flanking components. In this most comprehensive and accurate model of outer rings to date, the almost complete Y complex structure exhibits much tighter interaction in the hub region. In addition to two copies of Y complexes, each asymmetric subunit in CR contains five copies of Nup358, two copies of the Nup214 complex, two copies of Nup205 and one copy of newly identified Nup93, while that in NR contains one copy of Nup205, one copy of ELYS and one copy of Nup93. These in-depth structural features represent a great advance in understanding the assembly of NPCs.
3D bioprinted scaffolds for diabetic wound-healing applications
Authors: Glover Katie , Mathew Essyrose , Pitzanti Giulia , Magee Erin , Lamprou Dimitrios A. 
Published: January 2022

AbstractThe treatment strategy required for the effective healing of diabetic foot ulcer (DFU) is a complex process that is requiring several combined therapeutic approaches. As a result, there is a significant clinical and economic burden associated in treating DFU. Furthermore, these treatments are often unsuccessful, commonly resulting in lower-limb amputation. The use of drug-loaded scaffolds to treat DFU has previously been investigated using electrospinning and fused deposition modelling (FDM) 3D printing techniques; however, the rapidly evolving field of bioprinting is creating new opportunities for innovation within this research area. In this study, 3D-bioprinted scaffolds with different designs have been fabricated for the delivery of an antibiotic (levoflocixin) to DFU. The scaffolds were fully characterised by a variety of techniques (e.g. SEM, DSC/TGA, FTIR, and mechanical characterisation), demonstrating excellent mechanical properties and providing sustained drug release for 4 weeks. This proof of concept study demonstrates the innovative potential of bioprinting technologies in fabrication of antibiotic scaffolds for the treatment of DFU.
Graphical abstract
A Matter of Conscience: American Women Religious, Feminist Agency, and the Catholic Church
Authors: Murphy Ryan P. 
Published: January 2022

Background In 2012, the long-simmering tension between American women religious sisters and Catholic Church leadership was brought into sharp focus when the largest group of American sisters—the Leadership Conference of Women Religious—was reprimanded by the Vatican's Congregation for the Doctrine of the Faith. The Doctrinal Assessment and subsequent Apostolic Visitation concluded that American religious sisters embraced a secular and radical feminist spirit that was incompatible with Church doctrine. Purpose While American women religious were publicly criticized, this conflict is not a unique American phenomenon. In fact, it is representative of the gendered challenges that women religious and lay women continue to negotiate around the globe. In many respects, religious sisters are the faces of the Church to many faithful—as teachers, social workers, advocates, and ministers—yet their structural position as women prevents them from leadership or decision-making power in the Church they serve. Methods In this research, I explore how sisters navigate these gendered boundaries in the Catholic Church in their day to day ministries. Specifically, I analyze in-depth, semi-structured interviews with 23 Sisters of St. Joseph of Philadelphia. Results Sisters in this congregation employ various forms of feminist agency to assert their power within the Church's confining structures. I find that individual sisters in the congregation use resistance and empowerment agency to claim space for their own voices in ministry. These actions do not directly challenge the sisters’ own subordination in the Church, but instead focus their individual and collective agency on satisfying the unmet pastoral needs of the faithful. Through these accumulative actions, other sisters are empowered to contest gendered institutional Church boundaries and individual clergy who reproduce them. Conclusions and implications These sites of empowerment and resistance agency are liminal spaces that point toward greater inclusion of women religious in the institutional Catholic Church, especially as they increasingly meet the ministerial needs of the faithful. Religious sisters in this congregation act with socially-just consciences, standing with the marginalized, and are empowered to increase their spheres of influence in the locations where they minister.
Influence of binder systems on sintering characteristics, microstructures, and mechanical properties of PcBN composites fabricated by SPS
Authors: Chen Shuna , Fan Hengzhong , Su Yunfeng , Li Wensheng , Li Jicheng , Yan Bing , Song Junjie , Hu Litian , Zhang Yongsheng 
Published: January 2022

AbstractCubic boron nitride (cBN) with high hardness, thermal conductivity, wear resistance, and chemical inertness has become the most promising abrasive and machining material. Due to the difficulty of fabricating pure cBN body, generally, some binders are incorporated among cBN particles to prepare polycrystalline cubic boron nitride (PcBN). Hence, the binders play a critical factor to the performances of PcBN composites. In this study, the PcBN composites with three binder systems containing ceramic and metal phases were fabricated by spark plasma sintering (SPS) from 1400 to 1700 °C. The sintering behaviors and mechanical properties of the composites were investigated. Results show that the effect of binder formulas on mechanical properties mainly related to the compactness, mechanical performances, and thermal expansion coefficient of binder phases, which affect the carrying capacity of the composites and the bonding strength between binder phases and cBN particles. The PcBN composite with SiAlON phase as binder presented optimal flexural strength (465±29 MPa) and fracture toughness (5.62±0.37 MPa·m1/2), attributing to the synergistic effect similar to transgranular and intergranular fractures. Meanwhile, the excellent mechanical properties can be maintained a comparable level when the temperature even rises to 800 °C. Due to the weak bonding strength and high porosity, the PcBN composites with Al2O3-ZrO2(3Y) and Al-Ti binder systems exhibited inferior mechanical properties. The possible mechanisms to explain these results were also analyzed.
Culture shapes preschoolers’ emotion recognition but not emotion comprehension: a cross-cultural study in Germany and Singapore
Authors: Möller Corina , Bull Rebecca , Aschersleben Gisa 
Published: January 2022

AbstractContemporary approaches suggest that emotions are shaped by culture. Children growing up in different cultures experience culture-specific emotion socialization practices. As a result, children growing up in Western societies (e.g., US or UK) rely on explicit, semantic information, whereas children from East Asian cultures (e.g., China or Japan) are more sensitive towards implicit, contextual cues when confronted with others’ emotions. The aim of the present study was to investigate two aspects of preschoolers’ emotion understanding (emotion recognition and emotion comprehension) in a cross-cultural setting. To this end, Singaporean and German preschoolers were tested with an emotion recognition task employing European-American and East Asian child’s faces and the Test of Emotion Comprehension (TEC; Pons et al., 2004). In total, 129 German and Singaporean preschoolers (mean age 5.34 years) participated. Results indicate that preschoolers were able to recognize emotions of child’s faces above chance level. In line with previous findings, Singaporean preschoolers were more accurate in recognizing emotions from facial stimuli compared to German preschoolers. Accordingly, Singaporean preschoolers outperformed German preschoolers in the Recognition component of the TEC. The overall performance in TEC did not differ between the two samples. Findings of this study provide further evidence that emotion understanding is culturally shaped in accordance with culture-specific emotion socialization practices.
Veränderung von Interesse und Selbstwirksamkeitsüberzeugungen Grundschullehramtsstudierender im Bereich der politischen Bildung
Authors: Lenzgeiger Barbara 
Published: January 2022

ZusammenfassungEs gibt nur wenige Erkenntnisse zu den Ausprägungen von Lehrkraftinteresse und Lehrkraftselbstwirksamkeitsüberzeugungen (angehender) Grundschullehrkräfte im Bereich der politischen Bildung. Offen bleibt außerdem, inwieweit sich Interesse und Selbstwirksamkeitsüberzeugungen von angehenden Grundschullehrkräften verändern lassen. Zur Beantwortung dieser Frage wurden im Rahmen einer quasi-experimentellen Interventionsstudie Daten von N = 145 Studierenden des Lehramts für die Grundschule erhoben. Die Ergebnisse aus Strukturgleichungsmodellen und Regressionsanalysen zeigen, dass sich die Lehrkraftselbstwirksamkeitsüberzeugungen im Bereich der politischen Bildung durch eine Interventionsmaßnahme in Form eines Seminars verändern lassen. Jedoch waren keine Veränderungen des Lehrkraftinteresses der angehenden Lehrkräfte im Rahmen der Studie möglich. Gründe für diese Ergebnisse sowie Konsequenzen für die Ausbildung von Grundschullehrkräften werden diskutiert.