bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neurological manifestations in SARS‐CoV‐2 infection: A single‐center cross‐sectional study in Malaysia
Authors: Tan Hui Jan , Goh Cheon Han , Khoo Ching Soong , Ng Chen Fei , Tan Juen Kiem , Wan Zaidi Wan Asyraf , Law Zhe Kang , Zulkifli Muhamad Danial , Md Rani Shahrul Azmin , Wan Yahya Wan Nur Nafisah , Remli Rabani , Mohamed Ibrahim Norlinah , Hod Rozita , Mohamed Mukari Shahizon Azura , Mohd Mustapha Aida‐Widure Mustapha , Kori Najma , Periyasamy Petrick 
Published: October 2022

AbstractBackgroundNeurological involvement associated with SARS‐CoV‐2 infection has been reported from different regions of the world. However, data from South East Asia are scarce. We described the neurological manifestations and their associated factors among the hospitalized COVID‐19 patients from an academic tertiary hospital in Malaysia.MethodsA cross‐sectional observational study of hospitalized COVID‐19 patients was conducted. The neurological manifestations were divided into the self‐reported central nervous system (CNS) symptoms, stroke associated symptoms, symptoms of encephalitis or encephalopathy and specific neurological complications. Multiple logistic regression was performed using demographic and clinical variables to determine the factors associated with outcome.ResultsOf 156 hospitalized COVID‐19 patients with mean age of 55.88 ± 6.11 (SD) years, 23.7% developed neurological complications, which included stroke, encephalitis and encephalopathy. Patients with neurological complications were more likely to have diabetes mellitus (p = 0.033), symptoms of stroke [limb weakness (p < 0.001), slurred speech (p < 0.001)]; and encephalitis or encephalopathy [confusion (p < 0.001), forgetfulness (p = 0.006) and seizure (p = 0.019)]. Unvaccinated patients had a 4.25‐fold increased risk of having neurological complications (adjusted OR = 4.25; 95% CI: 1.02, 17.71, p = 0.047). Anosmia and dysgeusia were less associated with neurological complications (adjusted OR = 0.22; 95% CI: 0.05, 0.96, p = 0.044). The odds of neurological complications were increased by 18% in patients with leukocytosis (adjusted OR = 1.18, 95% CI: 1.003, p = 0.0460).ConclusionsStroke, encephalitis and encephalopathy were the common neurological complications from our study. Diabetes mellitus, presence of symptoms of stroke, symptoms of encephalitis or encephalopathy, leukocytosis, and being unvaccinated against COVID‐19 were the associated risk factors of developing neurological complications.
Application of Oblique Lateral Interbody Fusion Combined with Bridge‐Locking Cage in Adjacent Segment Disease After Lumbar Fusion
Authors: Zhang Shuai , Xu Hui , Yin Cheng‐hui 
Published: October 2022

ObjectiveAdjacent segment disease (ASD) is considered any abnormal process that develops in the mobile segment next to spinal fusion, accompanied by related symptoms. To evaluate the efficacy and complications of oblique lateral interbody fusion (OLIF) combined with bridge‐locking fusion on ASD after lumbar fusion.MethodsA total of 35 ASD patients who required re‐operation after lumbar fusion in our hospital from March 2014 to March 2020 were retrospectively analyzed, among which 13 cases (seven males and six females; 62.3 ± 11.3 years old) received the treatment of OLIF + bridge‐locking cage internal fixation (OLIF group), and 22 cases (14 males and eight females; 52.3 ± 17.8 years old) received the treatment of transforaminal lumbar interbody fusion (TLIF) + pedicle screw fixation (TLIF group). The comparison of the operation time, intraoperative blood loss, postoperative drainage volume, and length of hospital stay between the two groups of patients was performed using the t‐test. The comparison of Visual Analogue Scale (VAS) and Oswestry Disability Index (ODI) at different time points before and after the operation was performed using analysis of variance for repeated measurement data. The fusion rate and postoperative complications of the two groups of patients were also evaluated.ResultsThe operation time of patients in the OLIF group (55.4 ± 12.4 min) was significantly shorter than that of patients in the TLIF group (94.3 ± 22.9 min) (P < 0.05), the length of stay of patients in the OLIF group (7.4 ± 2.3 day) was significantly shorter than that of patients in the TLIF group (12.4 ± 3.2 day) (P < 0.05); the intraoperative blood loss (62.2 ± 30.1 mL) and postoperative drainage (47.3 ± 22.4 mL) of patients in the OLIF group were significantly less than those of patients in the TLIF group with intraoperative blood loss (363.4 ± 120.2 mL) and postoperative drainage (285.5 ± 57.8 mL) (all Ps < 0.05). Besides, the VAS and ODI scores of the two groups of patients were improved 3 months after the operation and at the last follow‐up (all Ps < 0.05). Three patients in the OLIF group developed complications such as hip flexion weakness and fusion cage sink, with an incidence of 23.1%. Three patients in the TLIF group developed complications including wound infection and intraoperative nerve injury, with an incidence of 22.7%.ConclusionThe combination of OLIF and bridge‐locking cage may be a safe and effective therapy for ASD patients after lumbar fusion operation.
Inability to perform ‘en bloc’ pulmonary vein isolation requiring ablation of the intervenous carina increases recurrence of atrial fibrillation: A meta‐analysis
Authors: Vamos Mate , Saghy Laszlo , Jankelson Lior , Garber Leonid , Pap Robert 
Published: October 2022

AbstractIntroductionFailure to isolate ipsilateral pulmonary veins (PV) “en bloc” by wide‐area circumferential ablation (WACA) may necessitate ablation at the intervenous carina. It is unknown how this scenario impacts rates of atrial fibrillation (AF) recurrence.MethodsA standard random‐effect meta‐analysis of randomized or observational studies were performed, where the outcome of first‐time AF ablation was reported in patients with “en bloc” isolation of PVs by WACA as compared with those in whom ablation at the intervenous carina was needed after WACA to achieve complete isolation.ResultsA total of five single‐center, observational studies (N = 1185) and one, multi‐center randomized trial (N = 234) were enrolled. PV isolation could be achieved by WACA “en bloc” in 902/1419 (63.6%) cases. The rest required additional ablation at one or both of the left and right intervenous carinas to achieve isolation. The follow‐up time after ablation ranged from 1 to 2 years in the included trials. The incidence of AF recurrence proved to be significantly lower in patients with successful “en bloc” isolation compared to those requiring carina ablation(s) to achieve complete bilateral PV isolation (MH‐OR 1.89, 95% CI 1.42–2.53, p < .01)ConclusionThis present meta‐analysis demonstrates a lower arrhythmia recurrence rate in patients with bilateral “en bloc” isolation, as compared to those who needed additional carina ablation for complete PVI. Therefore, it is imperative that every effort be made to isolate ipsilateral PVs “en bloc” during PVI.
Linking plant functional genes to rhizosphere microbes: a review
Authors: Liu Qi , Cheng Lang , Nian Hai , Jin Jian , Lian Tengxiang 
Published: October 2022

SummaryThe importance of rhizomicrobiome in plant development, nutrition acquisition and stress tolerance is unquestionable. Relevant plant genes corresponding to the above functions also regulate rhizomicrobiome construction. Deciphering the molecular regulatory network of plant‐microbe interactions could substantially contribute to improving crop yield and quality. Here, the plant gene‐related nutrient uptake, biotic and abiotic stress resistance, which may influence the composition and function of microbial communities, are discussed in this review. In turn, the influence of microbes on the expression of functional plant genes, and thereby plant growth and immunity, is also reviewed. Moreover, we have specifically paid attention to techniques and methods used to link plant functional genes and rhizomicrobiome. Finally, we propose to further explore the molecular mechanisms and signalling pathways of microbe‐host gene interactions, which could potentially be used for managing plant health in agricultural systems.
Intracranial hemangioma‐associated cranial nerve VII palsy treated with propranolol in an infant with possible PHACE syndrome
Authors: Zamil Dina H. , Fernandez Joan K. , Brown Danielle N. , Kralik Stephen F. , Herd Tiffany J. 
Published: October 2022

AbstractA 2‐week‐old infant with a large vascular birthmark involving her right face presented with right‐sided facial paralysis. MRI of the brain revealed multiple intracranial hemangiomas, and the hemangioma within the right temporal bone impinged on the facial nerve, which resulted in paralysis. Cranial nerve palsies are a rare neurological manifestation of PHACE syndrome. We report successful treatment of the facial nerve palsy with oral propranolol.
Feasibility of using a patient‐reported outcome measure into clinical practice following pediatric liver transplantation: The Starzl Network experience
Authors: Ng Vicky Lee , Dunphy Claire , Shemesh Eyal , Lobritto Steven , Eisenberg Elizabeth , Pomponi Claudia , Szolna Jonathan , Wilkerson Dawn , Gupta Nitika , Romero Rene , Perito Emily R. , DiPaola Frank , Gonzalez‐Peralta Regino P. , Hsu Evelyn , Saarela Katelyn , Mohammad Saeed , Superina Riccardo , Logan Sherrie , Miller Daniel W. , Krise‐Confair Cassandra , Swami Nehal , Mazariegos George ,   the Starzl Network
Published: October 2022

AbstractBackgroundPatient‐reported outcome measures (PROMs) are not routinely used in clinical care by pediatric liver transplant (LT) teams. The Starzl Network for Excellence in Pediatric Transplantation (SNEPT) assessed feasibility of using a disease‐specific Quality of Life (QoL) questionnaire in the ambulatory setting at 10 SNEPT sites.MethodsA mixed methods feasibility project assessing administration processes, barriers, and user experiences with the Pediatric Liver Transplant Quality of Life (PeLTQL) tool. Iterative processes sought stakeholder feedback across four phases (Pilot, Extended Pilot, Development of a Mobile App PeLTQL version, and Pilot App use).ResultsA total of 149 patient–parent dyads completed the PeLTQL during LT clinic follow‐up. Clinicians, parents, and patients evaluated and reported on feasibility of operationalization. Only two of 10 SNEPT sites continued PeLTQL administration after the initial two pilot phases. Reasons include limited clinical time and available personnel aggravated by the COVID‐19 pandemic. In response, a mobile application version of the PeLTQL was initiated. Providing PeLTQL responses electronically was “very easy” or “easy” as reported by 96% (22/23) parents.ConclusionsAdministration of a PROM into post‐pediatric LT clinical care was feasible, but ongoing utilization stalled. Use of a mobile app towards facilitating completion of the PeLTQL outside of clinic hours may address the time and work‐flow barriers identified.
Public health nurses’ perceptions and experiences of emergency preparedness, responsiveness, and burnout during the COVID‐19 pandemic
Authors: Gwon Seok Hyun , Thongpriwan Vipavee , Kett Paula , Cho Young 
Published: October 2022

AbstractObjective(s): To describe PHNs’ perceptions and experiences of the COVID‐19 pandemic, including training, response activities, and work‐related challenges.Design: This was a qualitative study using interpretive description for analysis.Sample: PHN participants who worked in public health departments in Wisconsin were recruited using purposive sampling. A total of 15 PHNs participated in the study, including both general and supervisor‐level PHNs.Measurements: Data were collected via semi‐structured interviews from March to May 2021. Interview questions focused on PHNs’ perceptions, experiences, response activities, and burnout in relation to the current pandemic as well as perceptions and experiences of emergency preparedness and response in general.Results: Five themes emerged in the study. These were: (1) experiences and observations of the COVID‐19 pandemic, (2) organizational changes and their impacts, (3) public health emergency preparedness and response, (4) public health emergency response activities, and (5) role strain and burnout.Conclusions: Findings presented here have important implications for PHN training and support in emergency preparedness and response. A wide array of strategies focused on developing and supporting the PHN workforce in response to the public health crisis this area need to be implemented at the organizational, community, and policy levels.
Real‐time delay announcement under competition
Authors: Singh Siddharth Prakash , Delasay Mohammad , Scheller‐Wolf Alan 
Published: October 2022

Internet‐based technology enables firms to disseminate real‐time delay information to delay‐sensitive customers. We study how such delay announcements impact service providers in a competitive environment with two service providers who compete for market share. We model the service providers' strategies based on an endogenous timing game, investigating strategies that emerge in equilibrium. We determine the service providers' market shares under the various game outcomes by analyzing continuous‐time Markov chains, which capture customers' joining decisions, and by developing a novel computational technique to analyze the intractable asymmetric Join‐the‐Shortest Queue system, providing bounds on the market shares. We find that only the lower capacity service provider announces its real‐time delay under intermediate system loads and highly imbalanced capacities. However, for most parameter settings, the mere presence of a competitor induces both providers to announce delays in equilibrium, leaving customers better off on average. We relate our findings to the single‐provider delay announcement literature by discussing the impact of competition on service providers, delay announcement technology firms, and customers.
Alpha and theta brain activity in 9‐month‐old infants during a live referential gaze paradigm
Authors: Angelini Laura , Tamburro Gabriella , Lionetti Francesca , Spinelli Maria , Comani Silvia , Zappasodi Filippo , Fasolo Mirco , Aureli Tiziana 
Published: October 2022

AbstractThe ability to establish a connection between the direction of the other's gaze and the object that is observed has important implications in the development of social cognition and learning. In this study, we analyzed alpha and theta band oscillations in one group of 9‐month‐old infants by implementing a face‐to‐face live paradigm, which presented the infants with a triadic social interaction with a real human being. We compared neural activations in two experimental conditions: Congruent and Incongruent gaze shift following the appearance of an object. In the Incongruent object‐gaze shift condition, we observed an increase of the theta power in comparison with the Congruent condition. We also found an enhancement of the alpha activity during the Congruent versus the Incongruent object‐gaze condition. These findings confirm the involvement of the theta and alpha band activity in the detection of the gaze of others when it shifts toward a referential target. We consider that the theta band modulation could be associated with the processing of unexpected events. Furthermore, the increase of the alpha band activity during the Congruent object‐gaze condition seems to be in agreement with prior findings on the mechanisms of internally controlled attention that emerge before the first year of life. The implementation of a live paradigm elicited a partially different oscillatory pattern in comparison with non‐live standard paradigms, supporting the importance of an ecological set‐up reproducing real‐life conditions to study the development of social cognition.
Agriculture, COVID‐19 and mental health: Does gender matter?
Authors: Budge Hannah , Shortall Sally 
Published: October 2022

AbstractAgriculture is one of the most precarious professions, being vulnerable to weather extremes and animal disease. As crises hit the agricultural sector, a growing awareness and concern for the mental wellbeing of farmers developed. Economic decline, climate change and culling animals all have a profound impact on affected farmers. To date, research has tended to focus on the farmer, typically a man, and not the farm family. This article considers the impact of Coronavirus (COVID‐19) on men and women on farms. Using qualitative interviews and focus groups, the impact of the pandemic on men's and women's work and social life within the family is explored. We found a differential impact. For farmers, usually men, COVID‐19 was generally a positive experience both in terms of work and social life. For women, on the other hand, COVID‐19 was found to have a negative impact on their work and social life. While gender equality in agriculture persists, women's equality in the workplace has advanced. However, with the pandemic, women worked from home on the farm. They experienced a regression in gender equality with traditional expectations of responsibility for childcare and housework returning. In addition, their emotional and ‘mental’ labour increased. We conclude that in the future, the mental health of men and women on farms needs to be considered when crises occur. Crises impact the farm family and different members of the family in dissimilar ways.
After rupture: Visions of history, African spirituality and theological repair in Nigerian Pentecostalism
Authors: Richman Naomi 
Published: October 2022

AbstractHow do Pentecostal Christians seek repair and renewal in their lives, after their efforts to rupture with the past and become born again? In this article, I wish to consider the ways that a group of Nigerian Pentecostals who belong to a deliverance church re‐narrativise their lives by constructing and entering into new timelines of history after their attempts to break with the past. This discursive project works to insert a notion of ‘Black Africa’ into an authentically Christian historical chronology that stretches far back into the biblical past and forward to the eschaton. In this way, Africa's unique spiritual character is seen as reflected not only in its reasserted claim to Christian history, but also in its eschatologically driven destiny to re‐evangelise the world. This tells us something about the theological way these Christians reframe their role in history, including how their understanding of a collective past shapes their vision of who they are in the present and will be in the future. In this article, I argue that more attention needs to be given to processes of repair, repositioning and realignment in discussions about how conversion to Pentecostalism can generate efforts to break away from what becomes conceptualised as ‘the past’.
Cytomegalovirus in the transplant setting: Where are we now and what happens next? A report from the International CMV Symposium 2021
Authors: Kotton Camille N. , Torre‐Cisneros Julián ,   The International CMV Symposium Faculty, Aguado José Maria , Alain Sophie , Baldanti Fausto , Baumann Gabriele , Boeken Udo , de la Calle Maria , Carbone Javier , Ciceri Fabio , Comoli Patrizia , Couzi Lionel , Danziger‐Isakov Lara , Fernández‐Ruiz Mario , Girmenia Corrado , Grossi Paolo Antonio , Hirsch Hans H. , Humar Atul , Kamar Nassim , Kotton Camille , Ljungman Per , Malagola Michele , Mira Estefania , Mueller Nicolas , Sester Martina , Teng Chieh‐Lin Jerry , Torre‐Cisneros Julian , Ussetti Piedad , Westall Glen , Wolf Dana , Zamora Marty 
Published: October 2022

AbstractThe CMV Symposium in September 2021 was an international conference dedicated to cytomegalovirus (CMV) infection after solid organ or hematopoietic stem cell transplantation. This review provides an overview of the presentations given by the expert faculty, supplemented with educational clinical cases. Topics discussed include CMV epidemiology and diagnosis, the burden of CMV infection and disease, CMV‐specific immunity and management of CMV in transplant settings. Major advances in the prevention and treatment of CMV in the past decade and increased understanding of CMV immunity have led to improved patient outcomes. In the future, management algorithms may be individualized based on the transplant recipient's immune profile, which will mark the start of a new era for patients with CMV.
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The impact of preservation fluid culture on graft site arteritis: A systematic review and meta‐analysis
Authors: Rinaldi Matteo , Bonazzetti Cecilia , Gatti Milo , Caroccia Natascia , Comai Giorgia , Ravaioli Matteo , Morelli Maria Cristina , Viale Pierluigi , Giannella Maddalena 
Published: October 2022

AbstractBackgroundThe role of culturing the graft preservation fluid (PF) is controversial and its impact on graft arteritis development remains unclear.MethodsSystematic literature search retrieving observational studies comparing solid organ transplant (SOT) recipients with culture‐positive PF versus culture‐negative PF. The quality of included studies was independently assessed according to the ROBINS‐I tool for observational studies. Meta‐analysis was performed using Mantel‐Haenszel random‐effect models. Graft site arteritis within 180 days from transplant was selected as the primary outcome.ResultsTwenty‐one observational studies (N = 2208 positive PF vs. 4458 negative) were included. Among positive PF, 857 (38.8%) were classified as high‐risk group pathogens and 1351 (61.2%) as low‐risk pathogens. Low‐risk and negative PF showed similar odds ratios. A significant higher risk of graft arteritis was found in SOT recipients with a PF yielding a high‐risk pathogen (odds ratio [OR] 18.43, 95% confidence interval [CI] 7.83–43.40) compared to low‐risk and negative PF, with low heterogeneity (I2 = 2.24%). Similar results were found considering separately high‐risk bacteria (OR 12.02, 95%CI 4.88‐29.60) and fungi (OR 71.00, 95%CI 28.07–179.56), with no heterogeneity (I2 = 0%), and in the subgroup analyses of the liver (OR 16.78, 95%CI 2.95–95.47) and kidney (OR 19.90, 95%CI 4.78–82.79) recipients. However, data about diagnostic features of graft arteritis were very limited, indeed for only 11 of the 93 events histological or microbiological results were reported.ConclusionsOur results may support the performance of PF culturing and a preemptive diagnostic or therapeutic management upon isolation of high‐risk pathogens. Further studies based on a reliable diagnosis of graft arteritis are needed.
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