bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigating the timing of catheter removal after traumatic bladder injury: a single-institution 12-year experience
Authors: Wilson Danielle J , Melin Isaac , Shah Nayan , O’Connor R Corey , Carver Thomas 
Published: February 2025

IntroductionTraumatic bladder injuries, although rare, may result in significant patient morbidity. Operative management is recommended for intraperitoneal (IP), mixed, and select extraperitoneal (EP) injuries. Current guidelines lack recommendations on catheter duration following operative repair and suggest follow-up cystography may be unnecessary for simple, repaired injuries. This has led to practice variation in postoperative management at our institution. We hypothesized that the trauma surgery service would have a shorter catheter duration and obtain fewer follow-up cystograms compared with the urology service, without increased complications.MethodsA retrospective review was conducted at a single level 1 trauma center between January 2010 and December 2022. All patients with traumatic bladder injuries during this period were included from the trauma registry. Those who were <18 years of age, lacked a full-thickness injury, died within 7 days of presentation, had a concomitant urethral injury or complex injury, did not undergo surgical repair, were lost to follow-up, underwent surgical management elsewhere, or had an iatrogenic injury were excluded. Data on patient demographics, management, and complications were recorded. Injuries were classified as complex when involving the trigone, ureters, or bladder neck, or were described as complex in the operative report.ResultsOf the 178 patients identified, 86 met the inclusion criteria. IP injuries were most common (43%), followed by EP (31%), and mixed (26%). Patient outcomes following the repair of simple injuries were similar regardless of the team performing the repair, although differences in catheter duration (11 days vs 17 days, p=0.006) and use of postoperative cystography (77% vs 100%, p<0.001) were observed (trauma vs urology, respectively).ConclusionVariations in postoperative management regarding catheter drainage and follow-up imaging for simple bladder repairs resulted in similar leak and complication rates. Our findings present an opportunity to reduce the duration of postoperative catheter drainage and cystography use in simple repairs.Level of evidenceIV.
Low‐Dose Oral Minoxidil in Lichen Planopilaris: Efficacy and Safety
Authors: Saber Mina , Dehghani Shaghayegh , Fatemi Naeini Farahnaz , Mohaghegh Fatemeh 
Published: February 2025

Background: Treating lichen planopilaris (LPP) is challenging for dermatologists. Along with anti‐inflammatory agents, another goal of treatment is to improve hair thickness in unaffected areas to cover the scars.Aim: To evaluate the effectiveness and safety of adding low‐dose oral minoxidil (OM) to the standard anti‐inflammatory treatment of LPP.Method: A total of 37 patients with LPP were randomly assigned to receive either 15 mg/week methotrexate (MTX) plus topical clobetasol or 1 mg/day minoxidil in addition to MTX plus clobetasol for 6 months. The Lichen Planopilaris Activity Index (LPPAI), dermoscopy, and standard photography evaluated the treatment efficacy.Results: Both groups exhibited a significant improvement in LPPAI (p < 0.001). The following signs/symptoms demonstrated notable improvements in frequency and/or severity in both groups: pruritus, anagen pull test, follicular prominency, scalp erythema, perifollicular erythema, milky red area, and pigmentation. However, pain, burning sensation, hair tufting, and spreading only improved in the MTX + low‐dose OM group. Elongated blood vessels did not improve in either group. In terms of hair thickness and density, there was no significant difference between the two groups.Conclusion: The addition of 1 mg/day minoxidil to the standard treatment of LPP was found to be safe but did not yield significant effects on LPPAI and hair density/thickness. Notably, two patients who received low‐dose OM (2/19, 10.5%) showed hair regrowth in scarring areas. Trials with higher doses of minoxidil may be promising.Trial Registration: Iranian Registry of Clinical Trials: IRCT20220528055005N1
Fast Degradation of MecciRNAs by SUPV3L1/ELAC2 Provides a Novel Opportunity to Tackle Heart Failure With Exogenous MecciRNA
Authors: Liu Xu , Wang Qinwei , Li Xinya , Yang Yan , Deng Yuqi , Wang Xiaolin , Wang Peipei , Chen Liang , Ma Likun , Shan Ge 
Published: February 2025

BACKGROUND:
Circular RNAs derived from both nuclear and mitochondrial genomes are identified in animal cells. Mitochondria-encoded circular RNAs (mecciRNAs) are attracting more attention, and several members of mecciRNAs have already been recognized in regulating mitochondrial functions. Mitochondria dysfunctions are well-known to participate in heart failure (HF). This study was designed to investigate the RNA metabolism of mecciRNAs and the relevant roles and potential application of mecciRNAs in HF.

METHODS:
Compared with highly stable nuclear genome-encoded circular RNAs, the fast degradation feature of mecciRNAs is identified by RNA sequencing and a series of molecular, biochemical, and cellular experiments. The substantial protective effects of in vitro synthesized mecciRNAs were tested in both doxorubicin- and pressure overload–induced mouse models of HF.

RESULTS:
We discover that mecciRNAs are promptly degraded by an animal-conserved complex of helicase SUPV3L1 (suppressor of var1, 3-like protein 1) and endoribonuclease ELAC2 (elaC ribonuclease Z 2). MecciRNA degradation complex and mecciRNAs interact with mitochondrial permeability transition pore and its regulators including TRAP1 (TNF receptor–associated protein 1) and CypD (cyclophilin D). MecciRNAs regulate mitochondrial levels of TRAP1 and CypD to modulate the opening of mitochondrial permeability transition pore and the release of mitochondrial reactive oxygen species. Exogenously applied mecciRNAs interact with cytosolic TRAP1 and increase mitochondrial levels of TRAP1, and lead to a more closed state of mitochondrial permeability transition pore to constrain deleterious reactive oxygen species release. HF conditions lead to stimulated mecciRNA degradation, and administration of in vitro synthesized mecciRNAs exhibits substantial protective effects in both doxorubicin- and pressure overload–induced mouse models of HF.

CONCLUSIONS:
This study demonstrates the fast degradation of mecciRNAs and the associated regulations of mitochondrial reactive oxygen species release of mitochondrial permeability transition pore by mecciRNAs. HF conditions lead to dysregulated mecciRNA degradation, and exogenous mecciRNAs demonstrate treatment potential in mouse models of HF.
Can Mosquitoes be Kin? Conservation, Conviviality, and Enmity Among “Pests” From Myanmar to Singapore
Authors: Cole Tomas 
Published: February 2025

Abstract
In this article, I take the theme of this special issue on “The Enemy of Kinship and Kinship with the Enemies” as a provocation to challenge previous work, including my own, on convivial conservation and interspecies kin-making across Southeast Asia. How do species spoken of as “pests” and “enemies” fit into models of interspecies relatedness? What happens when we focus on our particularly vexed interspecies relationship to disease-bearing bugs? Drawing on the figure of the mosquito, I proceed to probe the limits both of Indigenous practices of making good relations and kinship with other species, and of modes of interspecies kin-making that underpin them. I end by speculatively forwarding the notions of “making peace” as an alternative way of coexisting with species whom people regularly refuse to make kin, or even friends.
The Neurology of Culture
Authors: Lobo Gregory J. 
Published: February 2025

Abstract
The lack of anatomical evolution contrasted with an evident behavioral change in humans during their natural history, from about 200,000 to 700,000 years ago, constitutes something of a puzzle. What explains the behavioral change, a change which is commonly understood as cultural? Against the surprisingly widespread but tautological response that the change was driven by culture – which amounts to the unsatisfying argument that culture drives culture, all the way down, or back – this paper presents a theory developed by Andrey Vyshedskiy, whose work on autism and language therapies has led him to an account of the neurobiological basis of voluntary imagination, which here I redescribe as an account of the evolution of the neurology of culture.
Did Teddy Bears Culturally Evolve to Be Cuter? A Preregistered Replication
Authors: Borredon Quentin , Bulamac Zeynep , Crozat Camélia , Dayre Emmanuel , Fuchs Estelle , Hallo Marie , Kerzreho Lou , Lavagne d’Ortigue Pauline , Lellouche Theodore , Samani Hossein , Penel Sammy , Ryszefld Nina , Sandhu Tavleen , Timsit Aure , Yrjö-Koskinen Janne , Morin Olivier , Dubourg Edgar 
Published: February 2025

Abstract
This pre-registered replication study explores the impact of perceived cuteness on the evolution of cultural artifacts, testing whether neotenic traits – eye size, forehead height, and head roundness – have increased in teddy bears over time. In previous research, Hinde & Barden (1980) found an increase in teddy bear neoteny while Gould (1985) found that Mickey Mouse’s features became more neotenic with time. However, both studies lacked statistical power (15 teddy bears and 3 Mickey Mouse drawings). We collected data from eight major teddy bear manufacturers over nine decades (N = 250; 1900–1980). We found that the forehead height of teddy bears significantly increased over time. Conversely, our prediction that heads became rounder and eyes became bigger were not supported. We outline four key methodological limitations that future research should address to deepen our understanding of the cultural evolution of cuteness and of cultural artifacts more broadly – i.e., sampling bias, metadata inaccuracy, categorization ambiguity, and function ambiguity.
American-English Ethnoanatomy: Novices and Experts
Authors: Robbins Michael C. , Robbins Robert M. 
Published: February 2025

Abstract
This interdisciplinary study of novice, American–English speakers found two major discrepancies between their conceptualizations of external human anatomy, and the expert opinion of the scientific and medical community. In contrast to the experts, (1) more than 90% of the novices exhibit polysemy when identifying human limbs and (2) about 50% exhibit partonomic disagreement, about whether ‘thumbs’ are ‘fingers’, and ears are ‘parts of’ the face. Both verbal and visual test modalities were adopted in (2). No significant differences were found by modality in either case. Overall, the results about this cognitive domain support the frequent finding that, when compared to experts, novices tend to under-differentiate, making fewer specific distinctions, and use different taxonomic structures. A novel linguistic paradigm for explaining the specific findings is presented, as is their practical significance for health communications in general.
Resolution of Marital Disputes and Domestic Violence in Nigeria: The Role of Alternative and Traditional Dispute Resolution Mechanisms
Authors: Daibu Abdulrazaq Adelodun , Akanbi Khairat Oluwakemi , Jamiu Toheeb Aremu 
Published: February 2025

Abstract
Marital unions that are normally expected to be blissful and ever-lasting are sometimes riddled with all manner of disputes often resulting in domestic violence. This is because of the inevitability of disputes in human interactions including marital unions. Sometimes, for cultural and religious reasons, victims of domestic violence in marital disputes are warned against reporting the violence to ensure marriage sustainability, marital privacy as well as to protect the welfare of the children of the marriage among other reasons. This approach seems to be ineffective as endurance of domestic violence over time often results in physical injuries, anxiety, post-traumatic stress disorder and even death in some extreme cases. On the other hand, couples drag one another to different courts to seek legal redress and resolve marital disputes. Again, this approach does not seem to solve the problem. The court-based justice system has not proven to be a better forum of resolving connubial disputes that require confidential, swift, non-combative and effective dispute resolution mechanism. Hence, this article explores the possibility of using alternative dispute resolution mechanisms to solve marital disputes in Nigeria. It adopts the doctrinal research methodology to examine the role that alternative and traditional dispute resolution mechanisms could play in the amicable resolution of marital disputes and domestic violence cases. The article argues that alternative and traditional dispute resolution mechanisms could be more veritable and effective means of resolving matrimonial discords and domestic violence in Nigeria.
Optics, Heart Metaphors, and Print in the Age of Jesuit Science
Authors: Chen Andrew 
Published: February 2025

Abstract
This article examines some of the tensions and contradictions inherent in Athanasius Kircher’s (1602–1680) treatise Ars magna lucis et umbrae. In the concluding section of the work, Kircher likens the heart to the camera obscura and the mirror, using the vocabulary of optics to describe the purifying effect of divine light. The heightened evocativeness of this imagery came with theoretical difficulties, however, in part because of the negative spiritual connotations of reversal and inversion, operations performed by optical devices upon their objects. Kircher grappled with these challenges in other portions of his treatise. The fact that printmaking involves image reversal, and related errors in the illustrations of Ars magna lucis, complicated the situation further. It is argued here that the infelicities found in these illustrations offer a parallel, on the material level, for the conceptual difficulties negotiated by Kircher.
Causal relationship between Faecalibacterium abundance and risk of Faecalibacterium-related diseases: a two-sample bi-directional Mendelian randomisation study
Authors: Zhao S. , Qu Y. , Huang H. , Xie P. , Cai X. , Peng Q. , Peng J. , Zhang W. , Zhou H. , Yan H. , Li X. 
Published: February 2025

Abstract
Faecalibacterium is an essential probiotic in the human gut; changes in its abundance are associated with various disease states in many studies. However, the causal nature of such associations remains obscure. Therefore, we aimed to thoroughly investigate the causal relationships between Faecalibacterium and its related diseases. A two-sample bi-directional Mendelian randomisation analysis was conducted using publicly available genome-wide association studies summary statistics for Faecalibacterium and its related diseases. We found that Faecalibacterium was negatively correlated with the risk of ankylosing spondylitis (odds ratio [OR] = 0.526, 95% confidence interval [CI]:0.304-0.908, ), atopic dermatitis (OR = 0.484, 95%CI: 0.261-0.898, ) and heart failure (OR = 0.657, 95%CI: 0.467-0.924, ), while Faecalibacterium was positively associated with autism spectrum disorder risk (OR = 2.529, 95%CI: 1.012-6.319, ). The results of reverse Mendelian randomisation analysis showed that acute sinusitis (OR = 0.902, 95%CI: 0.839-0.970, ) and Alzheimer’s disease (OR = 0.976, 95%CI: 0.958-0.993, ) was causally associated with lower Faecalibacterium abundance, respectively, while cirrhosis (OR = 1.154, 95%CI: 1.028-1.295, ) and multiple myeloma (OR = 2.619 × 1012, 95%CI: 2.492-2.754 × 1024, ) was causally associated with higher Faecalibacterium abundance. Our findings firstly showed that changes in Faecalibacterium abundance may contribute to the risk of ankylosing spondylitis, atopic dermatitis, heart failure and autism spectrum disorders, and potentially as a result of acute sinusitis, Alzheimer’s disease, cirrhosis and multiple myeloma.
Introduction: Towards a History of Humanitarian Experiences
Authors: Martín-Moruno Dolores , Gorin Valerie 
Published: February 2025

Abstract
This special issue explores the evolving history of humanitarian experiences by bridging emotions, senses, and lived realities with broader social and political contexts. It challenges conventional definitions of humanitarianism by reframing it as a ‘cultivated feeling’ and examining its diverse embodiments across history. Contributions analyse how artists, children, volunteers, and professionals have shaped humanitarian actions, from anti-slavery movements to modern refugee aid, addressing ethical dilemmas, emotional dynamics, and systemic inequalities. By intertwining memory, imagination, and bodily practices, this collection reexamines humanitarianism’s roots and its transformation into a global movement. It critically interrogates the roles of emotions, offering a nuanced perspective on their historical intersections with senses and experiences. Ultimately, the issue advocates for an experiential turn, enriching the historical understanding of humanitarianism and its implications for contemporary and future practices.
Contribution of the Jesuits to the Development of Numismatics before the Suppression of the Society in 1773
Authors: Awianowicz Bartosz B. 
Published: February 2025

Abstract
The introductory essay explores the main aspects of the Jesuits’ contribution to the development of numismatics—the study and collection of coins, medals, and related objects—from using coins as inspiration for emblems and historical sources in the seventeenth century to the autonomous study of (mostly ancient) coins in the eighteenth century. In the seventeenth century, a philological approach prevailed among the Jesuits: Athanasius Kircher (1602–80) and Jean Hadrouin (1646–1729) were primarily interested in inscriptions on coins that could be used to help establish ancient biblical chronology. However, Louis Jobert (1637–1719) saw coins and later medals not only as historical sources but also as strictly collector’s objects. By the eighteenth century, the Jesuits were already present in every strand of numismatics at the time: they assembled their collections, cataloged the collections of rulers and institutions, wrote cross-sectional monographs, and took part in subtle academic polemics like the “Bellum Pollarum” (War over Polla) in Vienna in the 1760s.
Maine de Biran
Authors: Canullo Carla , Emma-Adamah Victor 
Published: February 2025

Abstract
Although phenomenology’s interest in the work of Maine de Biran is well known, the French philosopher’s work also marks an important path in hermeneutics, namely in what we can call “medical hermeneutics.” To paraphrase the famous phrase of Ricoeur’s hermeneutics, “to explain more in order to understand better,” medical hermeneutics would consist in explaining an illness in order to understand the body better. However, since there is an ambivalence of illness and health in a single body, it is precisely this duality or coexistence of principles that the treatment of illness in the body reveals to us. Thus, by developing Hermann Boerhaave’s phrase “homo simplex in vitalitate, duplex in humanitate,” Maine de Biran makes it possible to discover a radical duality in the unique human being, i.e. a radical and unconscious passivity and a conscious psychological state characterised by effort. This duality constitutes the complexity of the human being, which our philosopher also discovers thanks to his dialogue with the physicians of his time. Finally, thanks to this dialogue, Biran’s work can be inscribed in the history of the relationship between philosophy and medicine.
Traces of Gramscian Theory and Practice in South Africa
Authors: Ortu Claudia , Pontarelli Francesco 
Published: February 2025

Abstract
This study explores the reception and development of Antonio Gramsci’s political thought in South Africa, from the apartheid era to the late 2010s. By tracing Gramsci’s influence across academia and working-class organisations, the article argues that his categories emerged in response to intellectuals’ and movements’ needs for transformative praxis in specific historical periods. The paper employs a chronological and thematic framework, tracing how Gramsci’s thought was translated and developed by activist-intellectuals and trade unions during apartheid. It further explores the post-apartheid transition, investigating Gramsci-inspired analysis of neoliberal policies and the use of concepts like hegemony, civil society and, later on, passive revolution to address emerging crises and unmet expectations by the majority of the population. The study underscores Gramsci’s influence and enduring relevance in public debates and in analysing subaltern struggles and transformative potential within South African society.
Importance of Motor Control in “Static Situations” Where the Situation Does not Seem to Change
Authors: Nakajima Kento , Yamada Norimasa 
Published: February 2025

This study focuses on the human decision-making process under temporal and physical constraints. While previous studies have explored how humans respond rapidly to changing situations, this study examined situations that appear static but involve potential dynamic changes. Specifically, we used soccer as a context to analyze mistakes made in sports situations that seem static but assume potential movements and changes. The number of successful kicks and passes in static and quasi-static situations were compared, and the concept of information entropy was used for motion analysis to provide new insights. The results revealed that the number of successful passes in quasi-static situations significantly decreased (count: 320/400 times), indicating that even in quasi-static states, humans make decisions while anticipating dynamic situations, even in quasi-static states (Movement time: 853 ± 121 ms). During this time, there was a large variation (Entropy: 1.64, 1.86 bits) in the direction of the waist and the kicking motion at the moment of the kick. These findings indicate that motion is controlled in anticipation of dynamic situations, even under seemingly static conditions, and emphasize the importance of stability and accuracy in motor control across all situations. This study offers new insights into the psychological understanding of decision-making and behavioral control under complex and dynamic conditions with time constraints, contributing valuable knowledge to the field of psychology.