bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multisensory VR Experiences in Destination Management
Authors: Prodinger Barbara , Neuhofer Barbara 
Published: January 2022

AbstractThe rapid development of information and communication technologies (ICTs) and the high level of consumer acceptance have made it increasingly complex to retain loyal customers. Virtual Reality (VR) has become a solution that allows tourism providers to design technology-enhanced experiences along the entire customer journey. While most VR offers focus on pre-travel experiences, the potential of VR in the post-travel phase is still little explored. Considering that multisensory tourism experiences contribute to memory formation, the multisensory extension of VR (4D VR) in post-travel experiences is of interest. Thus, through a quantitative field experiment, this study aims to detect what effect the stimulation of different senses during the use of VR has on the overall experience and how this influences the brand relationship quality. The results revealed elevated levels of technology acceptance, which consequently enhances the traveler’s overall VR experience. The multisensory component positively affects one realm of an experience in the area of escapism and thus correlates with the overall experience. However, there is no significant difference between 3D and 4D regarding the level of brand relationship quality. The study expands the literature on 4D VR experiences and supports tourism practitioners in the implementation to strengthen the relationship between a destination and its guests.
An Exploratory Study of Consumers’ Travel-Related Concerns About COVID-19
Authors: Wei Wenqi , Önder Irem 
Published: January 2022

AbstractThis study explores consumers’ travel-related concerns about the COVID-19 pandemic via YouTube comments. Drawing on the risk perception theory and adopting a Markov Chain approach, this study demonstrates the topics that consumers discussed and empirically illustrates perceived risk in the tourism and hospitality industry via sentiment analysis across four sectors: recreation and entertainment, accommodation, transportation, and food and beverages. Results indicate discussion regarding travel-related videos is not only limited to travel-related topics but also includes a broad perspective of social, political, and historical topics. For instance, hotels have a new function as quarantine facilities with effective disease control procedures and social responsibility for public health. Additionally, health, performance, financial, social, and psychological risks are identified. Whereas the presence of travelers is typically regarded as positive, travelers during the crisis are regarded as “irresponsible” and “selfish” individuals who spread the virus and endanger public health. This shift of perception calls for both the industry and academia at large to educate people about the importance of disease control and rebuild travelers’ image and reputation. Recommendations to reduce the perceived risk in each sector are also provided.
Towards a Strengths-Based Personal Informatics Framework for Transformative Tourism Experiences: A Phenomenological Study on Serious Leisure Practitioners
Authors: Bruce Wan C. K. , de Bont Cees J. P. M. , Hekkert Paul , Chow Kenny K. N. 
Published: January 2022

AbstractPersonal technology plays an integral role in shaping people’s quality of life which includes leisure and tourism experiences. A number of personal informatics tools can support people in performing their activities by collecting biometric and environmental data; however, little is known regarding the use of psychological data to enrich leisure and tourism experiences. To address this research gap, this study aims to propose a conceptual framework that fosters memorable and meaningful leisure experiences (MMEs) based on theories from serious leisure and positive psychology. In particular, this study probes into the MMEs of serious leisure practitioners who put their efforts and resources into pursuing intrinsically rewarding leisure activities. Excelling at these activities, which may draw upon participants’ character strengths, yields sustained fulfillment which fosters personal transformation. The idiosyncratic nature of MMEs demands a phenomenological inquiry that involves in-depth interviews concerning the character strengths used and their development trajectories. Using theory triangulation from both positive psychology and serious leisure allows researchers to gain a holistic view of participants’ well-being. Character strengths were found to be the integral factors that contribute to MMEs at different stages of leisure activities. The result identified three aspects of strengths used: strengths well spent, reflection and introspection, and anticipation of the future self, which informs the development of a strengths-based personal informatics framework for leisure and tourism.
Destination Image of DMO and UGC on Instagram: A Machine-Learning Approach
Authors: Egger Roman , Gumus Oguzcan , Kaiumova Elza , Mükisch Richard , Surkic Veronika 
Published: January 2022

AbstractSocial media plays a key role in shaping the image of a destination. Although recent research has investigated factors influencing online users’ perception towards destination image, limited studies encompass and compare social media content shared by tourists and destination management organisations (DMOs) at the same time. This paper aims to determine whether the projected image of DMOs corresponds with the destination image perceived by tourists. By taking the Austrian Alpine resort Saalbach-Hinterglemm as a case, a netnographic approach was applied to analyse the visual and textual posts of DMO and user-generated content (UGC) on Instagram using machine learning. The findings reveal themes that are not covered in the posts published by marketers but do appear in UGC. This study adds to the existing literature by providing a deeper insight into destination image formation and uses a qualitative approach to assess destination brand image. It further highlights practical implications for the industry regarding DMOs’ social media marketing strategy.
Topic Modelling of Tourist Dining Experiences Based on the GLOBE Model
Authors: Egger Roman , Pagiri Angela , Prodinger Barbara , Liu Ruihong , Wettinger Fabian 
Published: January 2022

AbstractThe needs of travellers vary across cultures. When it comes to culinary aspects, there is a strong connection between gastronomy and culture. To optimise service offerings, investigation of the essential aspects of dining experiences in relation to cultural backgrounds is of great importance. In the age of digitalisation, tourists share their dining experiences throughout their multiphasic travel journey via online platforms. By considering nine distinct cultural backgrounds, this research aims to investigate tourist experiences based on TripAdvisor restaurant reviews through topic modelling, using the city of Salzburg as its study context. Depending on one’s cultural circumstances, the findings demonstrate that the most important aspects include staff, food-menu items, value for money, restaurant physical appearance, food authenticity, overall service, menu offers, food quality, atmosphere, and recommendations. This study advances the state-of-the-art knowledge of societal culture as a variable in the target market analysis of restaurant customers. Findings allow restaurant owners, other tourism service providers, and destination management organisations to analyse and adapt their service offerings and strategies accordingly.
Using the Behaviour Change Wheel to Design an App to Change Tourist Behaviour and Increase Dispersal into Regional Areas
Authors: Wells Martha , de Salas Kristy , Hardy Anne 
Published: January 2022

AbstractCurrently, many tourism destinations are experiencing greatly reduced tourism due to COVID-19. In order to ensure that regions that wish to engage in tourism can share the benefits of it more equally, and to prevent the predicted future problem of overuse of popular areas once pre-COVID visitor numbers resume, an app to encourage tourists and leisure-seekers to change their behaviour and disperse into regional areas has been developed. The Behaviour Change Wheel was used to define the problem, find suitable intervention functions and design methods of delivery that could increase tourists’ capability, opportunity and motivation to disperse farther into regions. The Huon Valley of Tasmania, Australia, was used as a research area. Our application of the Behaviour Change Wheel methodology determined that active engagement in logistic, value-based, and social information has the greatest chance of changing behaviour in this region and a list of Behaviour Change Techniques has been developed and considered in the design of a gamified travel app.
Exploring the Impact of Travel Vlogs on Prospect Tourists: A SOR Based Theoretical Framework
Authors: Li Wenliang , Kim Yoo Ri , Scarles Caroline , Liu Anyu 
Published: January 2022

AbstractIn recent years, travel vlogs are prevalent on social media, they are projected as an important marketing tool to attract tourists to destinations in the post-COVID-19 era. However, the underlying mechanism of how travel vlogs affect prospective tourists’ behaviours remains unclear. To address this gap, this paper discusses the applicability of the Stimulus-Organism-Response (SOR) model to travel vlog research and proposes a SOR based theoretical framework. Moreover, this paper highlights the increasing trend of the SOR model in both e-tourism and wider tourism and hospitality research.
Strong Law of Large Numbers for Iterates of Some Random-Valued Functions
Authors: Baron Karol , Kapica Rafał 
Published: January 2022

AbstractAssume $$ (\Omega , {\mathscr {A}}, P) $$

(
Ω
,
A
,
P
)

is a probability space, X is a compact metric space with the $$ \sigma $$
σ
-algebra $$ {\mathscr {B}} $$
B
of all its Borel subsets and $$ f: X \times \Omega \rightarrow X $$

f
:
X
×
Ω
→
X

is $$ {\mathscr {B}} \otimes {\mathscr {A}} $$

B
⊗
A

-measurable and contractive in mean. We consider the sequence of iterates of f defined on $$ X \times \Omega ^{{\mathbb {N}}}$$

X
×

Ω
N

by $$f^0(x, \omega ) = x$$

f
0

(
x
,
ω
)

=
x

and $$ f^n(x, \omega ) = f\big (f^{n-1}(x, \omega ), \omega _n\big )$$

f
n

(
x
,
ω
)

=
f

(

f

n
-
1

(
x
,
ω
)

,

ω
n

)

for $$n \in {\mathbb {N}}$$

n
∈
N

, and its weak limit $$\pi $$
π
. We show that if $$\psi :X \rightarrow {\mathbb {R}}$$

ψ
:
X
→
R

is continuous, then for every $$ x \in X $$

x
∈
X

the sequence $$\left( \frac{1}{n}\sum _{k=1}^n \psi \big (f^k(x,\cdot )\big )\right) _{n \in {\mathbb {N}}}$$

1
n

∑

k
=
1

n

ψ

(

f
k

(
x
,
·
)

)

n
∈
N

converges almost surely to $$\int _X\psi d\pi $$

∫
X

ψ
d
π

. In fact, we are focusing on the case where the metric space is complete and separable.
Radiation Dose and Fluoroscopy Time of Diagnostic Angiography in Patients with Spinal Dural Arteriovenous Fistula
Authors: Ozpeynirci Yigit , Trumm Christoph , Stahl Robert , Fischer David , Liebig Thomas , Forbrig Robert 
Published: January 2022

Abstract
Purpose
Spinal dural arteriovenous fistulas (SDAVFs) represent the most common indication for a spinal angiography. The diagnostic reference level (DRL) for this specific endovascular procedure is still to be determined. This single-center study provides detailed dosimetrics of diagnostic spinal angiography performed in patients with SDAVFs.

Methods
Retrospective analysis of all diagnostic spinal angiographies between December 2011 and January 2021. Only patients with an SDAVF who had baseline magnetic resonance angiography (MRA), diagnostic digital subtraction angiography (DSA), treatment and follow-up at this institution were included. Dose area product (DAP, Gy cm2) and fluoroscopy time were compared between preoperative and postoperative angiographies, according to SDAVF locations (common versus uncommon), MRA results at baseline (positive versus negative) and DSA protocols (low-dose, mixed-dose, normal-dose). The 75th percentile of the DAP distribution was used to define the local DRL.

Results
A total of 62 spinal angiographies were performed in 25 patients with SDAVF. Preoperative angiographies (30/62, 48%) yielded a significantly higher DAP and longer fluoroscopy time when compared to postoperative angiographies (32/62, 53%) (p < 0.01). The local DRL was 329.41 Gy cm2 for a nonspecific (n = 62), 395.59 Gy cm2 for a preoperative and 138.6 Gy cm2 for a postoperative spinal angiography. Preoperative angiography of uncommonly located SDAVFs yielded a significantly longer fluoroscopy time (p = 0.02). The MRA-based fistula detection had no significant impact on dosimetrics (p > 0.05). A low-dose protocol yielded a 61% reduction of DAP.

Conclusion
The results of the present study suggest novel DRLs for spinal angiography in patients with SDAVF. Dedicated low-dose protocols enable radiation dose optimization in these procedures.
Feeding Brassica vegetables to rats leads to the formation of characteristic DNA adducts (from 1-methoxy-3-indolylmethyl glucosinolate) in many tissues
Authors: Glatt Hansruedi , Engst Wolfram , Florian Simone , Schreiner Monika , Baasanjav-Gerber Chimgee 
Published: January 2022

AbstractJuices of Brassica vegetables are mutagenic and form characteristic DNA adducts in bacteria and mammalian cells. In this study, we examined whether such adducts are also formed in vivo in animal models. Rats fed raw broccoli ad libitum in addition to normal laboratory chow for 5 weeks showed one major adduct spot and sometimes an additional minor adduct spot in liver, kidney, lung, blood and the gastrointestinal tract, as determined by 32P-postlabelling/thin-layer chromatography. Adducts with the same chromatographic properties were formed when herring sperm DNA (or dG-3’-phosphate) was incubated with 1-methoxy-3-indolylmethyl glucosinolate (phytochemical present in Brassica plants), in the presence of myrosinase (plant enzyme that hydrolyses glucosinolates to bioactive breakdown products). UPLC–MS/MS analysis corroborated this finding: 1-Methoxy-3-indolylmethyl-substituted purine nucleosides were detected in the hepatic DNA of broccoli-fed animals, but not in control animals. Feeding raw cauliflower led to the formation of the same adducts. When steamed rather than raw broccoli was used, the adduct levels were essentially unchanged in liver and jejunum, but elevated in large intestine. Due to inactivation of myrosinase by the steaming, higher levels of the glucosinolates may have reached the large bowl to be activated by glucosidases from intestinal bacteria. In conclusion, the consumption of common Brassica vegetables can lead to the formation of substantial levels of DNA adducts in animal models. The adducts can be attributed to a specific phytochemical, neoglucobrassicin (1-methoxy-3-indolylmethyl glucosinolate).
Simultaneous measurement of intra-epidermal electric detection thresholds and evoked potentials for observation of nociceptive processing following sleep deprivation
Authors: van den Berg Boudewijn , Hijma Hemme J. , Koopmans Ingrid , Doll Robert J. , Zuiker Rob G. J. A. , Groeneveld Geert Jan , Buitenweg Jan R. 
Published: January 2022

AbstractSleep deprivation has been shown to increase pain intensity and decrease pain thresholds in healthy subjects. In chronic pain patients, sleep impairment often worsens the perceived pain intensity. This increased pain perception is the result of altered nociceptive processing. We recently developed a method to quantify and monitor altered nociceptive processing by simultaneous tracking of psychophysical detection thresholds and recording of evoked cortical potentials during intra-epidermal electric stimulation. In this study, we assessed the sensitivity of nociceptive detection thresholds and evoked potentials to altered nociceptive processing after sleep deprivation in an exploratory study with 24 healthy male and 24 healthy female subjects. In each subject, we tracked nociceptive detection thresholds and recorded central evoked potentials in response to 180 single- and 180 double-pulse intra-epidermal electric stimuli. Results showed that the detection thresholds for single- and double-pulse stimuli and the average central evoked potential for single-pulse stimuli were significantly decreased after sleep deprivation. When analyzed separated by sex, these effects were only significant in the male population. Multivariate analysis showed that the decrease of central evoked potential was associated with a decrease of task-related evoked activity. Measurement repetition led to a decrease of the detection threshold to double-pulse stimuli in the mixed and the female population, but did not significantly affect any other outcome measures. These results suggest that simultaneous tracking of psychophysical detection thresholds and evoked potentials is a useful method to observe altered nociceptive processing after sleep deprivation, but is also sensitive to sex differences and measurement repetition.
Analgesia in the Initial Management of Acute Pancreatitis: A Systematic Review and Meta‐Analysis of Randomised Controlled Trials
Authors: Thavanesan Navamayooran , White Sophie , Lee Shiela , Ratnayake Bathiya , Oppong Kofi W. , Nayar Manu K. , Sharp Linda , Drewes Asbjørn Mohr , Capurso Gabriele , De‐Madaria Enrique , Siriwardena Ajith K. , Windsor John A. , Pandanaboyana Sanjay 
Published: January 2022

AbstractBackgroundThe optimal analgesic strategy for patients with acute pancreatitis (AP) remains unknown.ObjectiveThe present systematic review and meta‐analysis aims to compare the efficacy of different analgesic modalities trialled in AP.MethodsA systematic search of PubMed, MEDLINE, EMBASE, CENTRAL, SCOPUS and Web of Science conducted up until June 2021, identified all randomised control trials (RCTs) comparing analgesic modalities in AP. A pooled analysis was undertaken of the improvement in pain scores as reported on visual analogue scale (VAS) on day 0, day 1 and day 2.ResultsTwelve RCTs were identified including 542 patients. Seven trial drugs were compared: opiates, non‐steroidal anti‐inflammatories (NSAIDs), metamizole, local anaesthetic, epidural, paracetamol, and placebo. Across all modalities, the pooled VAS scores showed global improvement from baseline to day 2. Epidural analgesia appears to provide the greatest improvement in VAS within the first 24 h but is equivalent to opiates by 48 h. Within 24 h, NSAIDs offered similar pain‐relief to opiates, while placebo also showed equivalence to other modalities but then plateaued. Local anaesthetics demonstrated least overall efficacy. VAS scores for opiate and non‐opiate analgesics were comparable at baseline and day 1. The identified RCTs demonstrated significant statistical and methodological heterogeneity in pain‐relief reporting.ConclusionsThere is remarkable paucity of level 1 evidence to guide pain management in AP with small datasets per study. Epidural administration appears effective within the first 24 h of AP although infrequently used and featured in only a single RCT. NSAIDs are an effective opiate sparing alternative during the first 24 h.
Peritoneal carcinosis in male germ cell tumor patients: a registry study compiled by the German Testicular Cancer Study Group (GTCSG)
Authors: Seidel Christoph , Hentrich Marcus , Zschäbitz Stefanie , Paffenholz Pia , Heidenreich Axel , Nestler Tim , Tran Ben , Fischer Stefanie , Daugaard Gedske , Ochsenreither Sebastian , Brito Margarida , Zengerling Friedemann , Schwab Constantin , Bokemeyer Carsten , Oing Christoph 
Published: January 2022

Abstract
Purpose
To report on the clinical characteristics, outcome, and frequency of peritoneal carcinosis (PC) in patients with advanced germ cell tumors (GCT), a multicenter registry analysis was carried out.

Methods
A multicenter registry analysis was conducted by the German Testicular Cancer Study Group (GTCSG) with international collaborators. Data was collected and analyzed retrospectively. Patients were eligible for inclusion if PC was diagnosed either by radiologic or histopathologic finding during the course of disease. Descriptive and explorative statistical analysis was carried out with cancer-specific survival (CSS) as primary study endpoint.

Results
Collaborators from ten GCT expert centers identified 28 GCT (0.77%) patients with PC after screening approximately 3767 GCT patient files and one case was contributed from a cancer registry request. Patients were diagnosed from 1997 to 2019 at a median age of 37 years (interquartile range, 13). Two patients (7%) presented with stage I and 27 patients (93%) with synchronous metastatic disease at first diagnosis. The primary histology was seminoma in seven (27%) and non-seminoma in 21 patients (72%). PC was detected after a median of 15.3 months from primary diagnosis (range 0–177) and two consecutive treatment lines (range 0–5), respectively. The median CSS from the time of detection of PC was 10.5 months (95%Confidence Interval 0.47–1.30) associated with an overall 2-year CSS rate of 30%.

Conclusion
PC represents a rare tumor manifestation in GCT patients and was primarily associated with the occurrence of advanced cisplatin-refractory disease conferring to a dismal prognosis.
The importance of time of day for magnetic body alignment in songbirds
Authors: Bianco Giuseppe , Köhler Robin Clemens , Ilieva Mihaela , Åkesson Susanne 
Published: January 2022

AbstractSpontaneous magnetic alignment is the simplest known directional response to the geomagnetic field that animals perform. Magnetic alignment is not a goal directed response and its relevance in the context of orientation and navigation has received little attention. Migratory songbirds, long-standing model organisms for studying magnetosensation, have recently been reported to align their body with the geomagnetic field. To explore whether the magnetic alignment behaviour in songbirds is involved in the underlying mechanism for compass calibration, which have been suggested to occur near to sunset, we studied juvenile Eurasian reed warblers (Acrocephalus scirpaceus) captured at stopover during their first autumn migration. We kept one group of birds in local daylight conditions and an experimental group under a 2 h delayed sunset. We used an ad hoc machine learning algorithm to track the birds’ body alignment over a 2-week period. Our results show that magnetic body alignment occurs prior to sunset, but shifts to a more northeast–southwest alignment afterwards. Our findings support the hypothesis that body alignment could be associated with how directional celestial and magnetic cues are integrated in the compass of migratory birds.