bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamics of functional genes and bacterial community during bioremediation of diesel-contaminated soil amended with compost
Authors: Yang Hyoju , Lee Jiho , Cho Kyung-Suk 
Published: June 2022

Abstract
Compost is widely used as an organic additive to improve the bioremediation of diesel-contaminated soil. In this study, the effects of compost amendment on the remediation performance, functional genes, and bacterial community are evaluated during the bioremediation of diesel-contaminated soils with various ratios of compost (0–20%, w/w). The study reveals that the diesel removal efficiency, soil enzyme (dehydrogenase and urease) activity, soil CH4 oxidation potential, and soil N2O reduction potential have a positive correlation with the compost amendment (p < 0.05). The ratios of denitrifying genes (nosZI, cnorB and qnorB) to 16S rRNA genes each show a positive correlation with compost amendment, whereas the ratio of the CH4-oxidizing gene (pmoA) to the 16S rRNA genes shows a negative correlation. Interestingly, the genera Acidibacter, Blastochloris, Erythrobacter, Hyphomicrobium, Marinobacter, Parvibaculum, Pseudoxanthomonas, and Terrimonas are strongly associated with diesel degradation, and have a strong positive correlation with soil CH4 oxidation potential. Meanwhile, the genera Atopostipes, Bacillus, Halomonas, Oblitimonas, Pusillimonas, Truepera, and Wenahouziangella are found to be strongly associated with soil N2O reduction potential. These results provide useful data for the development of technologies for improving diesel removal efficiency while minimizing greenhouse gas emissions in the bioremediation process of diesel-contaminated soil.
Prevalence and Consumption Pattern of Kolanut Among Pregnant Women in Ibadan Metropolis
Authors: Atiba F.A. , Popoola O.A. , Odukogbe A.O. , Ihunwo A.O. 
Published: June 2022

Abstract
Background
Kolanut is popular in Nigeria and other Sub-Saharan African countries where it is widely consumed in various social contexts. While some studies have suggested that kolanut is consumed by pregnant women, there is a dearth of information on the prevalence, consumption pattern and reasons for kolanut consumption.
Methods
This study investigated these gaps among pregnant women in Ibadan, Oyo State, Nigeria. A cross-sectional study involving 478 consenting pregnant women in all three trimesters and registered at health facilities in Ibadan was conducted. Semi-structured questionnaires were used to collect data on socio-demographic characteristics, obstetric history and kolanut use during pregnancy. Google mapping of all the addresses of the respondents was exported into ArcGIS online to generate the maps. Association between kolanut use and respondent characteristics was investigated using Chi-square test and logistic regression analysis.
Results
The mean age of the women was 28.7 ± 6.3 years, 50.8% had secondary level qualifications, 43.9% were semi-skilled workers. 38.7% were recruited in Primary Health Centres (PHCs), 18% from Secondary Health Centres, 22.6 from Tertiary Health Centres and 20.7 from Traditional Birth Assistants (TBA)/Faith Clinics. 162 (33.9%) of women reported kolanut in pregnancy and 140 (29.3%) in the index/current pregnancy. Frequency of use defined as high (every day), medium (thrice a week), low (≤ once a week) and quantity of use defined as high (≥ 1 nut at once), medium (half to < 1 lobe) and low (quarter to < half lobe). 26.9% reported frequent use, while 12.3% used in high quantity. A high consumption pattern was found with higher consumption at both Ibadan North East and Ibadan North Local Government areas. Significant associations were found between current kolanut use and Hausa respondents (p = 0.014), educational level; secondary (p = 0.032), tertiary (p = 0.006), TBA (p = 0.005). Majority (93.7%) used kolanut to prevent spitting, nausea, and vomiting.
Conclusion
This study has shown that kolanut use is common among pregnant women and it is consumed in large quantities. The results of this study justifyy research into consequences of kolanut use in pregnant women.
Combination effect of smoking conditions and Dunaliella salina as natural antioxidant on biochemical characters of stored Sander lucioperca fillets
Authors: Bouriga N. , Mili S. , Troudi D. , Atitallah A. Ben , Bahri W. Rjiba , Bejaoui S. , Quignard J.-P. , trabelsi M 
Published: June 2022

Abstract
Sander lucioperca is a fresh water fish characterized with its remarkable nutritional value. Thus, smoking improves sensory and microbiological characteristics. Therefore smoking processes is associated to alterations in some physicochemical fish properties. The object of this study is to evaluate the combined effects of two different processes of smoking (cold and hot) and natural antioxidants obtained from the microalgea Dunaliella salina administrated at two graded concentrations (+0.5pp and +1pp) on the biochemical quality and shelf life of Sander lucioperca fillets were investigated during 1, 20 and 90 days of storage.Smoking Sander lucioperca using Dunaliella salina extract increases polyphenols content in the fillets smoked fish. This natural antioxidant leads to a better preservation for this smoked fish. Dunaliella salina increases of the amounts of lipids and decreases TVBN, PV, TBARS and FFA in cold and hot smoked fillets. Therefore, combined effects of two different processes of smoking (cold and hot) and natural antioxidants could be a promising technique to preserve the Sander lucioperca fillets quality.
Light and zinc application treatment regulates yield and 2-acetyl-1-pyrroline (2AP) formation in fragrant rice
Authors: shuochen Jiang , Lihe Zhang , fenqin Hu , xiangru Tang , bin Du 
Published: June 2022

Abstract
Background
Improving the yield and aroma content of fragrant rice is the focus of fragrant rice research. Light (L) and Zinc (Zn) management generally cause regulations in the 2-acetyl-1-pyrroline (2AP) accumulation in fragrant rice. In addition, Zn promotes rice growth and improves rice yield, which has the potential to compensate for the negative impact of low light on fragrant rice yield. However, the potential of Zn to improve fragrant rice yield and 2AP content under shading conditions has not been verified.
Methods
Field experiments were conducted in the rice season (May-September) in 2019 to 2021. Two light i.e., normal light (NL) and low light (LL) and four Zn levels i.e., 0 kg Zn ha− 1 (N0), 1 kg Zn ha− 1 (Zn1), 2 kg Zn ha− 1(Zn2), and 3 kg Zn ha− 1 (Zn3), which applied at booting stage was set up. The grain yield, 2AP contents, Zn content in polish rice, photosynthesis related indicators, MDA content, antioxidant enzyme activity and the biochemical parameters related to 2AP formation were investigated.
Results
Shading reduced yield by 8.74% and increased 2AP content by 24.37%. In addition, shading reduced net photosynthetic rate (Pn), superoxide dismutase (SOD), peroxidase (POD) and catalase (CAT), and increased proline, γ-aminobutyric acid (GABA), and pyrroline-5-carboxylic acid (P5C), proline dehydrogenase (PDH), △1-pyrroline-5-carboxylic acid synthetase (P5CS), malondialdehyde (MDA). With increasing Zn application levels, yield, 2AP, Zn content in polish rice, Pn, proline, P5C, GABA, PDH, P5CS, SOD, CAT and POD increased, and MDA decreased. Significant L and Zn interaction effect on 2AP content was detected, and both shading and increasing Zn application increased the 2AP content.
Conclusion
Shading can increase the 2AP content but reduce the yield of fragrant rice. Increasing Zn application under shading conditions can further promote the biosynthesis of 2AP, but the effect of improving yield is limited.
Design and Psychometrics of the Sexual-Reproductive Needs and Concerns Scale of Iranian Never-Married Women Over 35
Authors: Taghizadeh Ziba , Ebadi Abbas , Shahrak Shakiba Pourasad , Brand Serge 
Published: June 2022

Abstract
Background
In traditional cultures, never-married women over 35 have to face a broad variety of social challenges. So far, no tool has been developed to measure the needs and concerns of these women. The purpose of the present study was to design the Farsi Scale of Sexual-Reproductive Needs and Concerns of never-married women over 35 and to assess its psychometric properties.
Methods
The combined exploratory study had two phases. In the first phase, we performed a qualitative study. We interviewed never-married Iranian women over 35; next, from their descriptions, we extracted specific items, and these items were aggregated to form items of a questionnaire. To psychometrically validate the questionnaire, we tested the validity (face, content, and structure) and reliability (internal consistency and stability) of the questionnaire. For evaluating the structural validity, a cross-sectional study of 240 never-married women over the age of 35 completed the questionnaire.
Results
The Sexual-Reproductive Needs and Concerns Scale of Iranian Never-Married Women over 35 was developed with 15 items and three dimensions (Emotional burden; Sexual needs; Stigma). Cronbach's alpha of the instrument was 0.81 and the Intraclass Correlation Coefficient was 0.98.
Conclusion
The results of the study showed that the developed scale has acceptable validity and reliability, and thus can be used to assess the sexual-reproductive needs and concerns of never-married Iranian women over 35.
In-silico investigations on the anticancer activity of selected 2-aryloxazoline derivatives that inhibit fatty acid synthase (FASN)
Authors: Rani Moly , Nath Ashutosh , Kumer Ajoy 
Published: June 2022

Abstract
As the in-silico study has become an important tool to search the new drugs in the concurrent era with towering acceptance and accuracy, it is executed in our research for unearthing the effective cancer drugs. To say more, breast cancer has accounted for the serious diseases for both men and women although few research outputs have been obtained on breast cancer that is not an adequate amount to ascertain new drugs. Due to this gap, the virtual screening, In-silico study, provides the ability to design and select by quickly identifying anticancer compounds with desirable drug-like properties. A total of nine 2-aryloxazoline derivatives were chosen, and In-silico was studied as a potential anticancer agent with the comparison of seven Food and Drug Administration (FDA) approved breast cancer drugs. These compounds were subjected to computational ADME and Lipinski analysis, as well as molecular docking and molecular dynamics simulations calculations against a variety of therapeutic targets involved in cell proliferation (PDB ID: 3TJM, 3ERT, 4OAR, 2J6M). An in-silico docking study reveals that ligands Hit-4, Hit-6, and Hit-8 had the highest docking scores of -10.3 kcal/mole − 10.3 kcal/mole, and − 10.2 kcal/mole towards Fatty Acid Synthase. The ligands had docking scores better than the standard anti-breast cancer drug gefitinib (− 5.3 kcal/mole). Our studies show the significance of pharmaceutical researchers in designing and developing new anticancer breast cancer drugs.
Association between oral health behavior and multiple chronic diseases among middle-aged and older adults in Beijing, China
Authors: Guo Dan , Shi Zhenyu , Luo Yanan , Ding Ruoxi , He Ping 
Published: June 2022

Abstract
Objectives: To evaluate the association between oral health behavior and multiple chronic diseases among middle-aged and older adults.Methods: Data from the Beijing Health Service Survey were used to estimate the association between oral hygiene behavior and risk of multiple chronic diseases using multivariate logistic models(N=18,158).Results: The risk of overall chronic diseases (OR=1.27, 95% CI:1.18~1.37), cardiovascular diseases (CVD, OR=1.30, 95% CI:1.21~1.39) and endocrine or nutritional metabolic disorders (OR=1.11, 95% CI:1.01~1.22) was higher in those who with poor oral health behavior. There was no significant correlation between oral health behavior and the risk of diseases of the musculoskeletal, respiratory, digestive, and genitourine systems.Conclusions: Poor oral hygiene practices were associated with a higher risk of overall chronic diseases, CVD and diabetes mellitus (DM) in middle-aged and older people. These findings motivate further studies to evaluate whether improved oral health behavior may prevent the incidence of chronic diseases.
Analysis of Inter-regional industrial relations of major industries in Sejong City
-using 2015 Korean Multiregional Input-Output Table
Authors: Lee Seongha , Ishiro Taku 
Published: June 2022

Abstract
South Korea's capital metropolitan area accounts for more than half of the country's total population and GDP. To overcome this phenomenon, the Korean government implemented various policies for the balanced development of the country, a representative of which was the construction of Sejong City in Chungcheong Province. Sejong City was established in July 2012, and by 2021, 44 government organizations and 15 state-run research institutes had migrated from metropolitan areas. In addition, it actively interacts with various cities in Daejeon, Chungcheongbuk-do, and Chungcheongnam-do, increasing its influence on the size of the economy and surrounding cities. Despite the importance of Sejong City, economic analysis after its establishment of Sejong City is still insufficient. Sejong City is expected to have clear regional characteristics in the public administration sector and research and development (R&D) for construction purposes. The education service industry is expected to revitalize because of the characteristics of the newly created city. Therefore, by using the 2015 Korean Multiregional Input-Output table, this study analyzes the industrial structure of Sejong City and Sejong's industrial characteristics and economic relations with other regions by measuring the industrial linkage between Sejong City and Chungcheong area, Seoul metropolitan area, and other regions by major industry.
Physical, static, and kinetic analysis of the electrochemical deposition process for the recovery of heavy metal from simulated industrial wastewater
Authors: Hamdi Ridha , Rached Amani , Massoudi Imen , Al-Otaibi Amal L. , Alkorbi Shouq , Ali Amor Saidi Ben 
Published: June 2022

Abstract
The electrochemical deposition has been used to recover lead, a harmful heavy metal, from simulated industrial wastewater. At constant potential, it is deposited onto fluorine-doped tin oxide (FTO) electrodes. Chronoamperometry was used to track its kinetic electrodeposition processes in situ for advanced nucleation stages at various temperatures. X-ray diffraction, scanning electron microscopy, and energy-dispersive X-ray techniques were used to investigate and characterize the deposits. The results show that the current density, as well as the density of the deposits, is strongly influenced by temperature. In this paper, we examine the relationship between experimental results and theoretical processes of lead deposits using 2D and 3D kinetic growth models.
NCoA3 upregulation in breast cancer-associated adipocytes elicits an inflammatory profile
Authors: Lira Maria Cecilia , Rosa Francisco Damian , Aiello Ignacio , Machado Mileni Soares , Palma Alejandra Graciela , Paz Leonardo Agustin , Güemes Maria Cecilia Salazar , Burlando Silvia , Azurmendi Pablo Javier , Paladino Natalia , Costas Monica Alejandra , Rubio Maria Fernanda 
Published: June 2022

Abstract
Purpose
NCoA3 is a transcriptional coactivator of NF-κB and other factors, present in undetectable levels into normal cells and amplified or overexpressed in several types of cancer, including breast tumors. We have previously demonstrated that NCoA3 levels decrease during adipogenesis, but its role in tumor-surrounding adipose tissue is still unknown. Therefore, in this work, we studied the modulation of NCoA3 in breast cancer-associated adipocytes and evaluated its correlation with the expression of inflammatory markers.
Methods
We collected mammary adipose tissue (MAT) from female mice that were stimulated with conditioned media from breast cancer cell lines or MAT adjacent to tumors from breast cancer patients. Then, the expression levels of NCoA3 were evaluated by qPCR and immunohistochemistry. TNF and MCP1 levels were measured. Ex vivo models were validated using 3T3-L1 cell lines and bioinformatics analysis.
Results
We found that in MAT samples expressing high levels of NCoA3 were mainly associated to a pro-inflammatory profile. Even more, patients with a worse prognosis and advanced clinical stage of disease showed high levels of this coactivator. Furthermore, in 3T3-L1 cell line-derived adipocytes, NCoA3 silencing or NF-κB inhibition reverted the expression of inflammatory molecules.
Conclusion
The modulation of NCoA3 levels in synergy with NF-κB activity in MAT in tumoral context, could be determinant factors to establish breast cancer-associated inflammation. As adipocytes are involved in the development and progression of breast cancer, this signaling network deserves to be further investigated to improve future tumoral treatments.
Predictive Model for Systemic Inflammatory Response Syndrome after Percutaneous Nephrolithotomy
Authors: Jakjaroenrit Nattawit , Tanthanuch Monthira , Bejrananda Tanan 
Published: June 2022

Abstract
Objective: To investigate the factors associated with systemic inflammatory response syndrome (SIRS) after percutaneous nephrolithotomy (PCNL) for upper urinary tract stones and establish a predictive model to prevent postoperative SIRS that correlates with PCNL. Methods: Patients who had undergone PCNL between June 2012 and December 2019 were retrospectively enrolled and categorized into groups according to their urosepsis status. Univariable and multivariate logistic regression analyses were performed to determine the predictive factors associated with SIRS after PCNL. Nomograms were generated using the predictors, and the discriminative ability was assessed using receiver operating characteristic (ROC) curve analyses. Results: A total of 262 PCNL patients were enrolled in this study, and SIRS occurred in 117 (44%) patients after PCNL. Multivariable logistic regression analysis suggested that there were three factors related to postoperative SIRS, namely stone size ≥ 3 cm (odds ratio [OR], 3.61; 95% confidence interval [CI], 2.08–6.26; p = 0.001), positive preoperative urine white blood cells (WBC) (OR, 3.1; 95% CI, 1.65–5.81; p = 0.028), and positive urine culture (OR, 2.89, 95% CI, 1.63–5.13; p = 0.017). According to the results of the logistic regression analysis, stone size ≥ 3 cm, positive preoperative urine WBC, and positive urine culture were used to develop the nomogram. A nomogram prediction model was established to calculate the cumulative probability of urosepsis after PCNL and displayed favorable fitting in the Hosmer–Lemeshow test (p=0.938). Internal validation of the nomogram showed that the area under the ROC curve was 0.702. Conclusion: Positive preoperative urine WBC, positive urine culture, and stone size ≥ 3 cm are the most significant predictors of SIRS after PCNL. The nomogram, which is based on independent risk factors, helps identify high-risk individuals and facilitates the early detection of SIRS after PCNL.
Significant miR-145-a genotypes to serve as asthma predictors
Authors: Wang Shou-Cheng , Tsai Chia-Wen , Chang Wen-Shin , Hsia Ning-Yi , Mong Mei-Chin , Wang Yun-Chi , Hsia Te-Chun , Gu Jian , Bau Da-Tian 
Published: June 2022

Abstract
Background: Asthma is a chronic airway inflammation disease and the diagnosis and treatment strategies remain difficult. The study and application of miRNAs have rapidly become one of the hot spots of translational medical sciences. There is no study confirming the contribution of the genotypes of miR-145 to asthma. We hypothesized the genotypes of miR-145 may influence the risk of asthma and aimed to test this hypothesis. Methods: In 198 asthma patients and 453 healthy controls, the genotypes of miR-145 rs4705342 and rs4705343 were determined, and the correlation of miR-145 genotypes with asthma severity were evaluated.Results: The distribution of miR-145 rs4705342 genotypes between asthma patients and non-asthmatic control groups were significantly different (p=0.0187). In detail, the variant CC genotypes were of lower proportions in asthma patients than in controls (OR=0.41, 95%CI=0.21-0.79, p=0.0102). The allele frequency analysis also showed a significantly differential distribution between the two groups (OR=0.69, 95%CI=0.53-0.90, p=0.0070). As for rs4705343, there was no such differential distribution. In addition, miR-145 rs4705342 variant genotypes were correlated with the symptom severity (p=3×10-5). Further, from the genotype-phenotype observation, there was a trend that C allele carriers prone to have a lower miR-145 expression level in their serum (p=0.0001). Conclusions: Our data provide evidence for miR-145 to serve as a novel biomarker for asthma risk prediction and early detection.
Increasing spatial and temporal resolution in energy system optimization model – the case of Kenya
Authors: Moksnes Nandi , Howells Mark , Usher William 
Published: June 2022

Abstract
At the time of writing 759 million people (2019) still lack access to electricity globally. Energy planning is important to describe plausible pathways to achieve national goals, where energy systems models are tools to explore scenarios and provide insight. Until recently, modelling energy access in countries with a low electrification rate was conducted at low spatial (e.g. national) and/or temporal resolution (e.g. annual time slices or ‘overnight’ electrification). In this paper, we develop methods in an open-source computational workflow with high spatial and medium temporal resolution in OSeMOSYS. We use Kenya as our case application where still 16 million people lack access to electricity (2019). The spatial resolution of approximately 40x40km cells leads to 591 demand cells split between electrified and un-electrified. Results show that a key limitation of PV + battery systems is that they struggle to provide peak demand. This manifests itself in very high marginal costs at peak times. That high marginal cost drives a transition of the system to mini-grid and grid connections as soon as demand levels are high.
Case Report of Protruded Implantable Cardiac Device Through Chest in 50 years old male
Authors: Alrajhi Abdulaziz , Alsultan Mohammed , Alotaibi Lama , Alshudukhi Ahmed 
Published: June 2022

Abstract
Abstract:
Background:
Implantable cardiac defibrillators use has been increasing for the last two decades and they are prone to infections. ICD device infection risk factors are many, some are host related while the others are procedures related.Staphylococcus aureus and staphylococcus epidermidis are accountable for 65 to 75% of the total cases of Implantable cardiac devices infections.

Case presentation:
A 50 years old male presented to our emergency department with ICD pocket migrated through the skin. The symptoms started over 2 weeks, started as gradual feeling of foreign body moving underneath the skin, associated with mild pain and 3 days before presentation, the ICD penetrated the skin. The patient denied any history of fever, bleeding, pus discharge, palpitations, abnormal shocks or syncope. He was admitted to the hospital, treated for a presumed infection and his ICD device was removed.

Conclusion:
ICD devices complications are many, including infections. But, to have an infected device protruded through the skin is not a common presentation. We outlined the approach that was taken for this patient and his management in order to enhance the literature in terms of the above mentioned rare presentation