bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pediatric reference interval verification for 17 specialized immunoassays and cancer markers on the Abbott Alinity i system in the CALIPER cohort of healthy children and adolescents
Authors: Bohn Mary Kathryn , Wilson Siobhan , Schneider Randal , Massamiri Youssef , Randell Edward W. , Adeli Khosrow 
Published: September 2022

Abstract

Objectives
Clinical laboratory investigation of autoimmune, metabolic, and oncologic disorders in children and adolescents relies on appropriateness of reference intervals (RIs). The Canadian Laboratory Initiative on Pediatric Reference Intervals (CALIPER) previously established comprehensive pediatric RIs for specialized immunoassays on the Abbott ARCHITECT system. Herein, we aim to verify performance on new Alinity i assays by evaluating sera collected from healthy children as per Clinical and Laboratory Standards Institute (CLSI) EP-28A3C guidelines.

Methods
Precision, linearity, and method comparison experiments were completed for 17 specialized Alinity immunoassays, including cancer antigens, autoimmune peptides, and hormones. Sera collected from healthy children and adolescents (birth-18 years, n=100) were evaluated. CLSI-based verification was completed using previously established CALIPER RIs for ARCHITECT assays as the reference.

Results
Of 17 specialized immunoassays assays, only anti-cyclic citrullinated peptides (anti-CCP) did not meet acceptable verification criterion (i.e., ≥90% of results within ARCHITECT reference CI). Anti-thyroglobulin, anti-thyroid peroxidase, and carcinoembryonic antigen did not require age-specific consideration beyond one year of age, with 63, 91, and 80% of samples equalling the limit of detection, respectively. Estimates were separated by sex for relevant assays (e.g., sex hormone binding globulin, total and free prostate specific antigen).

Conclusions
Findings support transferability of pediatric RIs on ARCHITECT system to the Alinity system for 16 specialized immunoassays in the CALIPER cohort and will be a useful resource for pediatric clinical laboratories using Alinity assays. Further work is needed to establish evidence-based interpretative recommendations for anti-CCP and continue to evaluate pediatric RI acceptability for newly available assay technologies.
Supporting the transition to practice: preceptor behaviors that foster a positive student preceptorship experience
Authors: Flott Elizabeth , Ball Sarah , Manz Julie , Beiermann Trisha , Khanna Maya M. 
Published: September 2022

Abstract

Objectives
Preceptors support nursing students when transitioning to the professional nursing role. This study explored student perceptions of preceptor characteristics that promoted or hindered learning.

Methods
A Likert-scale survey including two open-ended questions was sent to 571 nursing students completing a preceptorship experience. Descriptive statistics were used to analyze responses to the Likert-scale items. Qualitative analysis was completed on the two exploratory questions to extract themes.

Results
Students rated the preceptor between 4=Very Good and 5=Outstanding for all items. No significant differences in scores were found when comparing results between programs. Themes assisting in learning included: increasing independence gradually and pushing out of comfort zone. Themes identified that hindered learning included: doubting self and being pushed aside.

Conclusions
Future implications include communicating preceptorship objectives and providing ways to apply research to practice. These findings can guide collaboration between academic and practice partners to assist with transition to practice.
Does the pandemic hamper or boost the necessity for an international language? A survey on English use frequency among Japanese workers
Authors: Terasawa Takunori 
Published: September 2022

Abstract
This study aims to reveal the impact of the COVID-19 pandemic on the necessity of using English as an international language. For this purpose, this study conducted a web survey of Japanese workers, and statistically examined the extent to which the use of English increased or decreased after the outbreak. The findings are as follows. First, although some types of use decreased or increased, the majority did not show substantial changes. Second, the changes in English use were largely influenced by worker factors, such as types of occupation and employment (e.g. it declined typically among sales workers but not among the self-employed and freelancers), the degree of remote working (e.g. not being allowed to work remotely reduced it), and industry (e.g. it declined among workers in accommodation and real estate sectors but increased among public servants). These findings suggest the following implications: (1) non-decline in English use would suggest its resilience as an international language, the necessity of which could endure even in such a global upheaval; and (2) the frequency of using English (and other modes of international communication) is relatively independent of reduced human mobility, but it is largely affected by the economic climate.
Die Digitalisierung der Pressedokumentation beim Deutschen Bundestag – Ein problemorientierter Rückblick (Teil 1)
Authors: Sator Klaus 
Published: September 2022

Zusammenfassung
In der Pressedokumentation beim Deutschen Bundestag wurde in Zusammenhang mit dem Umzug des deutschen Parlaments von Bonn nach Berlin im Jahr 1999 ein elektronisches Produktions-, Rechercheund Archivsystem eingeführt. In einem problemorientierten Rückblick werden die damit verbundenen Veränderungen in Beziehung gesetzt zu den an seine Einführung geknüpften Zielen und Erwartungen. In diesem ersten Teil des Beitrags steht die technische Seite der Digitalisierung des Pressearchivs im Vordergrund. Sie veränderte die Arbeitsabläufe und eröffnete Chancen für neue Informationsdienstleistungen der Pressedokumentation. Die damit einhergehenden lizenz- und presserechtlichen Veränderungen haben Auswirkungen auf die Bestandsbildung.
Can Causal Powers Cause Their Effects?
Authors: Raimondi Andrea 
Published: September 2022

AbstractCausal Dispositionalism provides an account of causation based on an ontology of causal powers, properties with causal essence. According to the account, causation can be analysed in terms of the interaction of powers and its subsequent production of their effect. Recently, Baltimore, J. A. (2022. “Dispositionalism, Causation, and the Interaction Gap.”Erkenntnis87: 677–92) has raised a challenge against two competing approaches, the compositional view (CV) and the mutual manifestation view (MMV), to explain what makes powers interactive –the interaction gap. In this paper, we raise the challenge of explaining what makes powers productive –the production gap. While Baltimore’s verdict is tentatively favouring (MMV), we find both approaches wanting. Our conclusion is that Causal Dispositionalists should take Baltimore’s and our critique seriously. Powers cannot cause their effects just by bearing the name “causal”. To deserve their names, more metaphysical details are needed.
Hesitant versus confident family language policy: a case of two single-parent families in Finland
Authors: Vorobeva Polina 
Published: September 2022

Abstract
During the past decade, the field of family language policy has broadened its scope and turned its attention to diverse family configurations in versatile sociolinguistic contexts. The current study contributes to this endeavor by focusing on two single-parent families who live in Finland and who strive to support Russian as a family language. Applying nexus analysis as an epistemological stance and as an analytical lens, the study takes an emic perspective on family language policy. Furthermore, it examines how family language policy is manifested and negotiated during mother–child play and what discourses shape it. The findings reveal two contrasting ways in which family language policy is manifested and negotiated in the families. Confident family language policy in one of the families is informed by the mother’s historical body (i.e., prior experience of raising children bilingually), while in the other family, discourse in place represented by divergent language ideologies plays a significant role in shaping family language policy and is connected with hesitant decisions about language use in the family.
The crystal structure of 5-azido-1-methyl-4-nitroimidazole, C4H4O2N6
Authors: Huipeng Zhao , Pengbao Lian , Cai Cao , LiZhen Chen , Jianlong Wang 
Published: September 2022

Abstract
C4H4O2N6, monoclinic, P21/c (no. 14), a = 11.633(3) Å, b = 8.899(3) Å, c = 6.7638(18) Å, β = 105.216(12)°, V = 675.6(4) Å3, Z = 4, Rgt
(F) = 0.0607, wRref
(F
2) = 0.1617, T = 170 K.
Discerning users of information: A qualitative analysis of student inquiry
Authors: Krueger Karla Steege , Taylor Joan Bessman 
Published: September 2022

AbstractSchool Librarians are poised to lead a shift in information and digital literacy instruction with a growing emphasis on the evaluation of information sources, a need precipitated by widespread societal sharing of mis- and disinformation. What does the inquiry learning process look like when a team of students creates an innovative solution to a problem they identified through project-based research? And does such research enable students to practice the skills necessary to be discerning across information contexts? The information literacy instruction woven throughout the project contributed to the visible successes in student inquiry-based learning. And the skills necessary to be a discerning user of information were enabled through inquiry-based learning and would benefit from collaborative librarian instruction. Implications for school librarians point to teaching components from this project that are recommended for similar units (project scenario, process rubric, librarian background research packet, time to do research, librarian-led group discussion of focus, teacher prompts, teacher and mentor arranging expert visits, and a panel of judges) and those needed for future collaboration (scaffolding for searching for and tracking relevant sources, teaching complex note taking to decipher credible authors and sources, categorizing notes and sources by points of view, and citing sources to corroborate evidence).
Jointly Rayleigh lifetime products in the presence of competing risks model
Authors: Badr Souha K. , Abu-Zinadah Hanaa 
Published: September 2022

Abstract
In this article, we are applying the competing risks model of product from two different lines of production. So, the comparative life test is done under type-II censoring scheme with consideration of only two independent causes of failure. The statistical analysis procedures are developed considering joint sample of production and its life distributed with the Rayleigh lifetime distribution. The point estimation and the corresponding asymptotic confidence interval of the model parameters under maximum likelihood are constructed. Two bootstrap confidence intervals, bootstrap-

p

p

, and bootstrap-

t

t

, are discussed. Also, Bayesian approach to estimate point and credible interval is constructed. The estimation results are discussed through data set analyses. The validity of theoretical results is assessed and compared through Monte Carlo study. Finally, some of the points are reported as a brief comment.
Introduction: Race and Landscape in Nazi Germany*
Authors: Vollgraff Matthew 
Published: September 2022

Abstract
This article introduces the themes and contributions of this special issue on Art and Environment in the Third Reich. The work of architect and reformer Paul Schultze-Naumburg is examined as a case study of the aestheticization of ‘race’ and landscape from the Wilhelmine Period to the National Socialism, particularly as it bore on German colonization and settlement projects in eastern Europe. Today’s resurgent far right and environmental crisis, it is argued, lend new urgency to critical interrogation of the relationship between environmental politics and the visual representation of nature under fascism. The articles collected in this issue illustrate a range of interdisciplinary approaches that move beyond iconography to address alternative media, materialities, and environmental history.
The Painter Werner Peiner, the Culture of the German Oil Industry, and the Nature of Hitler’s State
Authors: van Dyke James A. 
Published: September 2022

Abstract
This article examines the monumental mosaics, large stained glass windows, and illustrated maps that the German painter Werner Peiner (1897–1984), now best known for his designs for the representative buildings of Hitler’s dictatorship, produced between 1931 and 1935 for Shell Oil and its German subsidiary. The discussion of these commissions, which emerged from Peiner’s social networks of the 1920s and contributed to his career as a state artist after 1933, explains their function as ideological images promoting the interests of a global corporation and affirming modern automotive technology using conservative, mythologizing tropes of paradisical nature, traditional cultural landscapes, and immutable national communities that the painter later employed in his work for Hitler’s state.
Enzyme–substrate interface targeting by imidazole‐based γ‐secretase modulators activates γ‐secretase and stabilizes its interaction withAPP
Authors: Petit Dieter , Hitzenberger Manuel , Koch Matthias , Lismont Sam , Zoltowska Katarzyna Marta , Enzlein Thomas , Hopf Carsten , Zacharias Martin , Chávez‐Gutiérrez Lucía 
Published: September 2022

AbstractAlzheimer's disease (AD) pathogenesis has been linked to the accumulation of longer, aggregation‐prone amyloid β (Aβ) peptides in the brain. Γ‐secretases generate Aβ peptides from the amyloid precursor protein (APP). Γ‐secretase modulators (GSMs) promote the generation of shorter, less‐amyloidogenic Aβs and have therapeutic potential. However, poorly defined drug–target interactions and mechanisms of action have hampered their therapeutic development. Here, we investigate the interactions between the imidazole‐based GSM and its target γ‐secretase—APP using experimental andin silicoapproaches. We map the GSM binding site to the enzyme–substrate interface, define a drug‐binding mode that is consistent with functional and structural data, and provide molecular insights into the underlying mechanisms of action. In this respect, our analyses show that occupancy of a γ‐secretase (sub)pocket, mediating binding of the modulator's imidazole moiety, is sufficient to trigger allosteric rearrangements in γ‐secretase as well as stabilize enzyme–substrate interactions. Together, these findings may facilitate the rational design of new modulators of γ‐secretase with improved pharmacological properties.
Between Modernization and Capitalization: Commercialization of Malang in The Early Twentieth Century
Authors: Hudiyanto R Reza 
Published: September 2022

Abstract: Â Colonialism, capitalism, and the city are three elements that always correlated.Â At the beginning of the 20th-century cities, growth wasÂ inseparable from the economic expansion of Dutch capitalism represented by theÂ plantation industry, trade offices, insurance offices, and elite shopping areas. The exploitation of urban space followed this process.Â As the regime changed in early 1942, theÂ growth of the symbol of capitalism in the city was halted by the Japanese Military Government.Â This article attempts to explain the relationship between the development of capitalism, the modernization of the city, and its impact on society.Â To explain this connection, the author uses historical methods using the city government report.Â Based on analysis of municipal tax report and the response of indigenous people who lived within the city, it can be concluded that there is an influence of capitalism on the high intensity of exploitation and conflict in struggling for urban space.Â Modernization of the city is not merely efforts to create a city comfortable and hygienic, but the strategy of commerce urban space. Modernization of the colonial city has covered the suffering of most people that have their own way of living.Â Abstrak: Kolonialisme, kapitalisme dan kota adalah tiga unsur yang selalu berkorelasi. Pada awal abad ke-20 pertumbuhan kota tidak terlepas dari ekspansi ekonomi kapitalisme Belanda yang diwakili oleh industri perkebunan, perkantoran perdagangan, perkantoran asuransi dan kawasan perbelanjaan elit. Proses ini diikuti dengan eksploitasi ruang kota. Ketika rezim berganti pada awal 1942, pertumbuhan simbol kapitalisme di kota itu dihentikan oleh Pemerintah Militer Jepang. Artikel ini mencoba menjelaskan hubungan antara perkembangan kapitalisme, modernisasi kota dan pengaruhnya terhadap masyarakat. Untuk menjelaskan hubungan tersebut, penulis menggunakan metode sejarah dengan menggunakan laporan pemerintah kota. Berdasarkan analisis laporan pajak kota dan respon masyarakat adat yang tinggal bersama di kota dapat disimpulkan bahwa terdapat pengaruh kapitalisme terhadap tingginya intensitas eksploitasi dan konflik dalam memperebutkan ruang kota. Modernisasi kota bukan semata-mata upaya menciptakan kota yang nyaman dan bersih, tetapi strategi perdagangan ruang kota. Modernisasi kota kolonial telah menutupi penderitaan sebagian besar masyarakat yang memiliki cara hidup sendiri-sendiri.Â Â
The Dutch Position in World War II in Sedjarah Umum Textbook by Anwar Sanusi
Authors: Rusmiati Desi 
Published: September 2022

Abstract: This article discusses Sedjarah Umum written by Anwar Sanusi, namely the historiography of history textbooks in transitional historical records. At the beginning of Indonesia's independence, textbooks for history subjects was faced a non-centric and Indonesian-centric examination style. Neerlando-centric is a style that studies old historiography that is used mostly by colonial education. Choosing Indonesia-centric was a new style of writing after independence which had the purpose of writing a history that made the Indonesian nation the main actor. Still, it did not solve the history of Europeans in the Indies. The method used in this study is discourse analysis. The results of the study in this paper are (1) The writing of the Sedjarah Umum textbook written by Anwar Sanusi can be published using Neerlando centric and Indonesian centric; (2) The Dutch in World War II were shown as mediators and victims; (3) Indonesia-centric is indicated by mentioning Indonesia as a unified country. This study also compares textbooks published by the Sedjarah Umum of Anwar Sanusi's works based on the analysis: there are Neerlando centric and Indonesia-centric approaches.Â Abstrak: Artikel ini membahas tentang historiografi Sedjarah Umum karangan Anwar Sanusi yaitu historiografi buku ajar sejarah dalam masa transisi. Pada awal kemerdekaan Indonesia, buku teks pelajaran sejarah dihadapkan pada gaya ujian non sentris dan Indonesia sentris. Neerlando-sentris adalah gaya yang mempelajari historiografi lama yang sebagian besar digunakan oleh pendidikan kolonial. Memilih Indonesia-sentris adalah gaya penulisan baru setelah kemerdekaan yang bertujuan untuk menulis sejarah yang menjadikan bangsa Indonesia sebagai pemeran utamanya, tetapi tidak menyelesaikan sejarah bangsa Eropa di Hindia Belanda. Metode yang digunakan dalam penelitian ini adalah analisis wacana. Hasil penelitian dalam makalah ini adalah (1) Penulisan buku teks Sedjarah Umum karangan Anwar Sanusi diterbitkan dengan menggunakan Nerlando centric dan Indonesian centric; (2) Belanda dalam Perang Dunia II ditampilkan sebagai mediator dan korban; (3) Indonesia-sentris ditunjukkan dengan menyebut Indonesia sebagai negara kesatuan. Studi ini juga membandingkan buku teks Sedjarah Umum Anwar Sanusi berdasarkan pendekatan Neerlando centric dan Indonesia-centric.Â Â
Food Insecurity Screening and Intervention in United States Children’s Hospitals
Authors: Markowitz Molly A. , Tiyyagura Gunjan , Quallen Kaitlin , Rosenberg Julia 
Published: September 2022

OBJECTIVES
Food insecurity (FI) affects many United States families and negatively impacts the health of children. We assessed patterns of FI screening for United States children’s hospitals, characterized screening protocols, and assessed how hospitals addressed general and inpatient-specific caregiver FI, including provision of food or meals for caregivers of admitted children.

METHODS
We conducted a cross-sectional, confidential survey of clinical team members at United States children’s hospitals. We evaluated FI screening practices and responses, including which team members conduct FI screening, the types of screeners used, and interventions including social work consultations, referrals to community resources, and provision of food or meals.

RESULTS
Of the 76 children’s hospital representatives (40% response rate) who participated in the survey, 67.1% reported at least some screening, and 34.2% performed universal screening for FI. Screening was conducted most frequently on the inpatient units (58.8%), with social workers (35.5%) and nurses (34.2%) administering screeners most frequently. Responses to positive screens included social work consultation (51.3%), referral to community resources (47.4%), and offering food or meals (43.4%). Eighty-four percent of hospitals provided food or meals to at least some caregivers for admitted pediatric patients. Conditional qualifications for food/meals included need-based (31.6%) and presence of breastfeeding mothers (30.3%).

CONCLUSIONS
Many United States children’s hospitals screen for FI, but most survey respondents reported that their hospital did not conduct universal screening. Screening protocols and interventions varied among institutions. Children’s hospitals could consider improving screening protocols and interventions to ensure that needs are identified and addressed.
Anatomía de un bicentenario: la tercera etapa de la exploración del Trienio Liberal
Authors: Salgues Marie 
Published: September 2022

Recension del libro: Ivana Frasquet, Pedro Rújula y Álvaro París (eds.), El Trienio Liberal (1820-1823). Balance y perspectivas, Prensas de la Universidad de Zaragoza e Institución “Fernando el Católico”, Zaragoza, 2022, 620 pp.
Enviado el (Submission Date): 23/04/2022Aceptado el (Acceptance Date): 17/05/2022
Atención primaria de salud en la Unidad Educativa Tumbaco en el período 2013-2016
Authors: Bahamonde Marisol , Yépez Martha 
Published: September 2022

La Escuela de Medicina de la Universidad San Francisco de Quito USFQ, en convenio con el Ministerio de Salud Pública (MSP) y con autorización del Ministerio de Educación, inició, en el año 2013, un proyecto de atención integral de salud en la Unidad Educativa Tumbaco. Este proyecto de vinculación a la comunidad se creó con el objetivo de atender a una población vulnerable para proveerle de mayores oportunidades de acceso al sistema de salud. Esta unidad educativa es un establecimiento público, con escuela y colegio en la que estudian aproximadamente 4000 niños y adolescentes de nuestra comunidad.
El propósito de este artículo es comparar las prestaciones de atención que se brindaron en este servicio de salud escolar durante el período 2013-2016, con las atenciones brindadas en un centro de atención primaria del MSP. En este estudio, se plantea que las principales causas de morbilidad en el servicio de salud escolar de la Unidad Educativa de Tumbaco entre los años 2013 y 2016 son similares a las principales causas de morbilidad establecidas por la base de datos del Registro Diario Automatizado de Consultas y Atenciones (RDACCA) del Instituto Nacional de Estadística y Censos (INEC) para el centro de salud de Tumbaco.