bluuebunny/crossref_metadata_2025_split huggingface dataset:
Robust 3D lane detection in complex traffic scenes using Att-Gen-LaneNet
Authors: Jiang Yanshu , Dong Qingbo , Deng Liwei 
Published: June 2022

AbstractRobust 3D lane detection is the key to advanced autonomous driving technologies. However, complex traffic scenes such as bad weather and variable terrain are the main factors affecting the robustness of lane detection algorithms. In this paper, a generalized two-stage network called Att-Gen-LaneNet was proposed to achieve robust 3D lane detection in complex traffic scenes. The Efficient Channel Attention (ECA) module and the Convolutional Block Attention Module (CBAM) were combined in this network. In the first stage of the network, we improved the semantic segmentation network ENet and proposed the weighted cross-entropy loss function to solve the problem of ambiguous distant lane segmentation. This method improved Pixel Accuracy to 99.7% and MIoU to 89.5%. In the second stage of the network, we introduced the interpolation loss function to achieve accurate lane fitting. This method outperformed existing detection methods by 6% in F-score and Average Precision on the Apollo Synthetic dataset. The proposed method achieved better overall performance in 3D lane detection and was applicable to broader and more complex traffic scenes.
Analysis of the entire mitochondrial genome reveals Leber’s hereditary optic neuropathy mitochondrial DNA mutations in an Arab cohort with multiple sclerosis
Authors: Al‐Kafaji Ghada , Alharbi Maram A. , Alkandari Hasan , Salem Abdel Halim , Bakhiet Moiz 
Published: June 2022

AbstractSeveral mitochondrial DNA (mtDNA) mutations of Leber's hereditary optic neuropathy (LHON) have been reported in patients with multiple sclerosis (MS) from different ethnicities. To further study the involvement of LHON mtDNA mutations in MS in the Arab population, we analyzed sequencing data of the entire mitochondrial genome from 47 unrelated Saudi individuals, 23 patients with relapse-remitting MS (RRMS) and 24 healthy controls. Ten LHON mutations/variants were detected in the patients but were absent in the controls. Of them, the common primary pathogenic mutation m.14484T>C and the rare mutation m.10237T>C were found in one patient, whereas the rare mutation m.9101T>C was found in another patient. The remaining were secondary single nucleotide variants (SNVs) found either in synergy with the primary/rare mutations or individually in other patients. Patients carrying LHON variants also exhibited distinct mtDNA variants throughout the mitochondrial genome, eight were previously reported in patients with LHON. Moreover, five other LHON-related SNVs differed significantly in their prevalence among patients and controls (P < 0.05). This study, the first to investigate LHON mtDNA mutations/variants in a Saudi cohort may suggest a role of these mutations/variants in the pathogenesis or genetic predisposition to MS, a possibility which needs to be explored further in a large-scale.
Experimental and modeling analyses of COD removal from industrial wastewater using the TiO2–chitosan nanocomposites
Authors: Heydari Orojlou Shahin , Rastegarzadeh Saadat , Zargar Behrooz 
Published: June 2022

AbstractIn the present study, titanium oxide (TiO2) nanoparticles, chitosan, and several nanocomposites containing different mass dosages of TiO2 and chitosan have been applied as the adsorbent for COD removal from the industrial wastewater (Bouali Sina Petrochemical Company, Iran). The FESEM, XRD, and FTIR tests have been employed to characterize TiO2 nanoparticles, chitosan, and fabricated nanocomposites. Then, the effect of adsorption parameters, including TiO2–chitosan mass ratio (1:1, 1:2, and 2:1), adsorbent content (0.25–2.5 g), temperature (20–50 °C), pH (3–11), solution volume (100–500 mL), and contact time (30–180 min) on the COD reduction has also been monitored both experimentally and numerically. The Box–Behnken design of the experiment approves that TiO2–chitosan (1:1), adsorbent content of 2.5 g, temperature = 20 °C, pH 7.4, solution volume of 100 mL, and contact time = 180 min are the condition that maximizes the COD removal (i.e., 94.5%). Moreover, the Redlich–Peterson and Pseudo-second order models are the best isotherm and kinetic scenarios to describe COD removal’s transient and equilibrium behaviors. The maximum monolayer COD adsorption capacity of the TiO2–chitosan nanocomposite is 89.5 mg g−1. The results revealed that the industrial wastewater COD is better to remove using the TiO2–chitosan (1:1) at temperature = 20 °C.
Gram-negative multidrug-resistant organisms were dominant in neurorehabilitation ward patients in a general hospital in southwest China
Authors: Jiang Wei , Li Lang , Wen Siyang , Song Yunling , yu Lehua , Tan Botao 
Published: June 2022

AbstractThis study aimed to investigate the prevalence of and risk factors for multidrug-resistant organism (MDRO) infection in the rehabilitation ward of a general hospital in Southwest China. We analyzed rehabilitation patients with nosocomial infections caused by MDROs from June 2016 to June 2020. MDRO infection pathogens and associated antibiotic resistance were calculated. Possible risk factors for MDRO-related infection in the neurorehabilitation ward were analyzed using chi-square, and logistic regression. A total of 112 strains of MDRO were found positive from 96 patients. The MDRO test-positive rate was 16.70% (96/575). Ninety-five MDRO strains were detected in sputum, of which 84.82% (95/112) were gram-negative bacteria. Acinetobacter baumannii (A. Baumannii), Pseudomonas aeruginosa (P. aeruginosa), and Klebsiella pneumonia (K. pneumonia) were the most frequently isolated MDRO strains. The logistic regression model and multifactorial analysis showed that long-term (≥ 7 days) antibiotic use (OR 6.901), history of tracheotomy (OR 4.458), and a low albumin level (< 40 g/L) (OR 2.749) were independent risk factors for the development of MDRO infection in patients in the rehabilitation ward (all P < 0.05). Gram-negative MRDOs were dominant in rehabilitation ward patients. Low albumin, history of a tracheostomy, and long-term use of antibiotics were independent risk factors for MRDO infection and are worthy of attention.
Light regulates chlorophyll biosynthesis via ELIP1 during the storage of Chinese cabbage
Authors: Wang Tuoyi , Liu Sijia , Tian Shaonan , Ma Tianyi , Wang Wei 
Published: June 2022

AbstractChlorophyll loss is a major problem during green vegetable storage. However, the molecular mechanism is still unclear. In this study, a 21 days of storage experiments showed chlorophyll content was higher in light-stored Chinese cabbage (Brassica chinensis L.) leaves than those in dark-stored samples. Transcriptome analyses were performed on these samples to determine the effects of light. Among 311 differentially expressed genes (DEGs), early light-induced protein 1 (ELIP1) was identified as the main control gene for chlorophyll synthesis. Tissues and subcellular localization indicated that ELIP1 was localized in the nucleus. Motifs structure analyses, chromatin immunoprecipitation (ChIP) assays, luciferase reporter assays, and overexpression experiments demonstrated that ELIP1 regulated the expressions of genomes uncoupled 4 (GUN4), Glutamyl-tRNA reductase family protein (HEMA1), and Mg-protoporphyrin IX methyltransferase (CHLM) by binding to G-box-like motifs and affected chlorophyll biosynthesis during the storage of Chinese cabbage. It is a possible common tetrapyrrole biosynthetic pathway for chlorophylls, hemes, and bilin pigments in photosynthetic organisms. Our research also revealed that white light can be used as a regulatory factor to improve the storage ability and extent shelf life of Chinese cabbage.
Role of GBP1 in innate immunity and potential as a tuberculosis biomarker
Authors: Shi Ting , Huang Linlin , Zhou Yulin , Tian Jianmei 
Published: June 2022

AbstractTuberculosis (TB) is a global health problem of major concern. Identification of immune biomarkers may facilitate the early diagnosis and targeted treatment of TB. We used public RNA-sequencing datasets of patients with TB and healthy controls to identify differentially expressed genes and their associated functional networks. GBP1 expression was consistently significantly upregulated in TB, and 4492 differentially expressed genes were simultaneously associated with TB and high GBP1 expression. Weighted gene correlation analysis identified 12 functional modules. Modules positively correlated with TB and high GBP1 expression were associated with the innate immune response, neutrophil activation, neutrophil-mediated immunity, and NOD receptor signaling pathway. Eleven hub genes (GBP1, HLA-B, ELF4, HLA-E, IFITM2, TNFRSF14, CD274, AIM2, CFB, RHOG, and HORMAD1) were identified. The least absolute shrinkage and selection operator model based on hub genes accurately predicted the occurrence of TB (area under the receiver operating characteristic curve = 0.97). The GBP1-module-pathway network based on the STRING database showed that GBP1 expression correlated with the expression of interferon-stimulated genes (GBP5, BATF2, EPSTI1, RSAD2, IFI44L, IFIT3, and OAS3). Our study suggests GBP1 as an optimal diagnostic biomarker for TB, further indicating an association of the AIM2 inflammasome signaling pathway in TB pathology.
Überlegungen zur Interaktionsbezogenen Fallarbeit (IFA) und
Balint-Arbeit in der zukünftigen Weiterbildung zum (Psychologischen)
Fachpsychotherapeuten
Authors: Grünbaum Johannes , Theilemann Steffen 
Published: June 2022

ZusammenfassungDas von den Psychotherapeutenkammern der Bundesländer vorgelegte
Kompetenzprofil für (Psychologische) Psychotherapeuten1 fordert für diese die Entwicklung
ihrer Fähigkeiten zur behandlungs- und patientenbezogenen
Selbstreflexion. Der Aufbau der benannten Fähigkeiten soll nun mit Hilfe
der zukünftigen Landesweiterbildungsordnungen zum Fachpsychotherapeuten
– dabei neu die Möglichkeit zur Interaktionsbezogenen Fallarbeit
(IFA) und der Balintgruppenarbeit enthaltend – abgesichert werden. Es
werden Argumente angeführt, welcher Gewinn aus der IFA und Balintarbeit
im Vergleich zu den sonstigen Formen von Supervision und Selbsterfahrung in
einer Weiterbildung zum Fachpsychotherapeuten resultiert und welche Gefahren bei
der Implementierung der IFA und der Balintarbeit in die Weiterbildungsordnungen
bestehen.
Questionários Disability of the Arm Shoulder and Hand e Michigan Hand: Explorando a responsividade e performance diagnóstica em amostra de pacientes ambulatoriais com e sem queixas nas mãos e punho
Authors: Moraes Vinícius Ynoe de , Faria Jamile Caroline Velasques , Fernandes Marcela , Raduan-Neto Jorge , Okamura Aldo , Belloti João Carlos 
Published: June 2022

Resumo
Objetivo Verificar se, em uma população adulta com queixa não traumática dos membros superiores, (1) os questionários Disability of the Arm, Shoulder and Hand (DASH, na sigla em inglês) e Michigan Hand Questionnaire (MHQ, na sigla em inglês) estão suscetíveis ao “efeito de teto”, comparando com amostra de não-doentes; (2) determinar pontos de corte de performance diagnóstica e correlação interquestionários para DASH e MHQ em ambas as amostras.
Método Estudo prospectivo, comparativo e não randomizado. Incluímos 150 pacientes, 75 no grupo caso (com doença) e 75 no grupo controle (sem doença). Trata-se de amostra de pacientes recém-admitidos em ambulatório de cirurgia da mão. Os controles foram pareados de forma balanceada de acordo com a inclusão dos casos. Determinamos a presença de efeito de teto por meio da taxa de respostas máximas (> 15%) e associamos curvas receiver operating characteristic (ROC, na sigla em inglês) para a determinação de pontos de corte para a determinação de doentes, associados a medidas de sensibilidade e especificidade. Consideramos p < 0.05 para significância estatística.
Resultados Os questionários DASH e MHQ não demonstraram o efeito de teto para o grupo com doença. A porcentagem de pacientes do grupo caso com nota máxima foi de n = 18 (24%) no DASH e de 0% no MHQ. Para o grupo sem doença, 1 (1,33%) dos participantes pontuou com nota máxima para DASH, enquanto nenhum pontuou para o MHQ. Na determinação de casos, escores de DASH de 7,1 apresentam sensibilidade de 80% e especificidade de 60,3%. Para o MHQ, um escore de 76,9 apresenta sensibilidade de 56,2% e especificidade de 97,3%.
Conclusão Os questionários DASH e MHQ são ferramentas confiáveis na mensuração do impacto das morbidades das mãos e dos punhos nas atividades diárias dos pacientes e não são suscetíveis a efeito de teto. O questionário DASH é mais sensível para a identificação de doentes, enquanto o MHQ é mais específico. Em situações nas quais se espera um incremento funcional mais discreto (ou mais específico), o MHQ parece mais adequado.
Updates in the Management of Recurrent Glioblastoma Multiforme
Authors: Prajapati Hanuman Prasad , Ansari Ahmad 
Published: June 2022

Abstract
Background Glioblastoma is the most aggressive and diffusely infiltrative primary brain tumor. Recurrence is almost universal even after all primary standard treatments. This article aims to review the literature and update the standard treatment strategies for patients with recurrent glioblastoma.
Methods A systematic search was performed with the phrase “recurrent glioblastoma and management” as a search term in PubMed central, Medline, and Embase databases to identify all the articles published on the subject till December 2020. The review included peer-reviewed original articles, clinical trials, review articles, and keywords in title and abstract.
Results Out of 513 articles searched, 73 were included in this review after screening for eligibility. On analyzing the data, most of the studies report a median overall survival (OS) of 5.9 to 11.4 months after re-surgery and 4.7 to 7.6 months without re-surgery. Re-irradiation with stereotactic radiosurgery (SRS) and fractionated stereotactic radiotherapy (FSRT) result in a median OS of 10.2 months (range: 7.0–12 months) and 9.8 months (ranged: 7.5–11.0 months), respectively. Radiation necrosis was found in 16.6% (range: 0–24.4%) after SRS. Chemotherapeutic agents like nitrosourea (carmustine), bevacizumab, and temozolomide (TMZ) rechallenge result in a median OS in the range of 5.1 to 7.5, 6.5 to 9.2, and 5.1–13.0 months and six months progression free survival (PFS-6) in the range of 13 to 17.5%, 25 to 42.6%, and 23 to 58.3%, respectively. Use of epithelial growth factor receptor (EGFR) inhibitors results in a median OS in the range of 2.0 to 3.0 months and PFS-6 in 13%.
Conclusion Although recurrent glioblastoma remains a fatal disease with universal mortality, the literature suggests that a subset of patients may benefit from maximal treatment efforts.
Health Care Workers' Adherence to Hand Hygiene Guidelines in Emergency Surgical Room of a Tertiary Care Hospital
Authors: Dhamnaskar Suchin Sudhakar , Chaudhari Gautami Milind , Koranne Mandar Sharadchandra 
Published: June 2022

Abstract
Background Out of every 100 hospitalized patients, 7 patients in advanced countries and 10 patients in emerging countries acquire health care-associated infections (HCAIs). Hand hygiene (HH) procedures are the simple and cost-effective solution to significantly reduce HCAI. We wanted to know the compliance rate of HH procedures among health care workers (HCWs) working in emergency surgical room (ESR) of our institute, so that feedback can be given to them and further interventions can be planned.
Methodology This is a cross-sectional observational study conducted in ESR. Resident doctors and faculties, interns, and nurses were directly observed for all the five moments of HH recommended by World Health Organization (WHO). The data have been recorded with the WHO recommended form for observation and basic compliance calculation for HH.
Results In total, 1,370 HH opportunities were observed and recorded, of which 690 were for resident doctors and faculties, and 340 each for interns and nurses. The overall total HH compliance rate among all HCWs was 41.3% and resident doctors and faculties had the poorest compliance. Poorest compliance was observed for moment 1, whereas maximum compliance was for moment 3 among all the HCWs.
Conclusion HCWs' adherence to HH guidelines in ESR of this tertiary care hospital is low and is least in resident doctors and faculties.
Association between elastography‐assessed muscle mechanical properties and high‐speed dynamic performance
Authors: Ema Ryoichi 
Published: June 2022

ABSTRACTClarifying the muscular factors that contribute to performance improvement can be beneficial for athletes and coaches. The present study examined the relationships between the resting muscle shear modulus and dynamic performance during the stretch‐shortening cycle (SSC) and explosive exercises. To this end, we measured the jump height during three types of vertical jumps (squat jump [SJ], countermovement jump [CMJ], and rebound jump [RJ]) and the multi‐joint leg extension power at three velocities (low, moderate, and high) of 30 healthy women. Using ultrasound elastography, the resting shear modulus of the vastus lateralis was assessed in the sitting position as an index of passive muscle mechanical properties. The results showed that the shear modulus was positively correlated with RJ height and multi‐joint leg extension power at moderate and high velocities (r = 0.435–0.563, P < 0.05). There was no significant correlation between the shear modulus and SJ height, CMJ height, and multi‐joint leg extension power at low velocity. Contact time (i.e. the time under force exertion against the ground) during RJ (161 ± 19 ms) was 19% of that during CMJ (869 ± 171 ms). The results suggest that passive muscle mechanical properties play an important role in high‐speed SSCs and dynamic explosive performance.
Health states assessment and prediction of manufacturing system based on brittleness
Authors: Liu Weiqiang , Xu Liyun 
Published: June 2022

Abstract
Accurate recognition of system health states is the key to ensure the safe operation of the system. In view of the shortcomings of the existing methods, a new method of manufacturing system health states assessment and prediction based on brittleness is proposed. Firstly, according to the real-time effective performance parameters, the brittle risk entropy model of equipment is constructed, and the brittleness of corresponding equipment on each station is calculated; Secondly, based on the structural characteristics of manufacturing system, the calculation model of system brittleness is constructed by analysing from equipment to system step by step, and the mapping relationship between system brittleness and health states is established to complete the assessment of system health states; Thirdly, based on the historical data samples, the quintic polynomial regression model of system brittleness and time is constructed to predict the future health states of system and the time nodes that need to be maintained. Finally, an assembly manufacturing system is taken as an example to verify the correctness and effectiveness of the proposed method.
Preparation of AQS/GO/PVDF redox mediator membrane and the decolorization of azo dyes
Authors: Huang Y. Y. , Ye Q. , Li J. , Lan C. F. , Lin X. S. 
Published: June 2022

Abstract
AQS/PVDF and AQS/GO/PVDF redox mediator membranes were prepared with poly (vinylidene fluoride) (PVDF) as the raw supporting material of membrane, anthraquinone-2-sulfonic acid (AQS) as the redox mediator, and graphene oxide (GO) as an additive by an immersion precipitation method. The AQS content in the redox mediator membrane was optimized with the formation performance of AQS/PVDF membrane. With the optimal casting solution for AQS/PVDF membrane, GO was introduced as an additive to form AQS/GO/PVDF membrane. The effects of the redox mediator membranes on the bacterial decolorization of dye wastewaters were investigated. The results suggest that both AQS/PVDF and AQS/GO/PVDF membranes can promote the bacterial decolorization of dyes and the introduction of GO improves the decolorization rate more significantly because it can accelerate the electron transfer. Therefore, the conductivity of GO and the electron shuttle of AQS show a synergetic effect on accelerating the bacterial decolorization of dyes.
Q-band polarizers for the LSPE-Strip correlation radiometric instrument
Authors: Peverini O.A. , Lumia M. , Farooqui Z. , Addamo G. , Virone G. , Paonessa F. , Ciorba L. , Zannoni M. , Gervasi M. , Franceschet C. , Bersanelli M. , Mennella A. , Cuttaia F. , Morgante G. , Villa F. , Jones M. 
Published: June 2022

Abstract
This paper reports the design, manufacturing and testing of
the cluster of polarizers developed for the LSPE-Strip correlation
receiver array working in the Q band (39–48 GHz). Since the LSPE
experiment targets the measurement of the very faint B-mode
component of the Cosmic Microwave Background, the electromagnetic
design of the polarizers was conceived in view of minimizing the
measurement uncertainties introduced by the polarizers in the
LSPE-Strip dual-circular-polarization correlation receiving
chain. To this end, the main figures-of-merit of the LSPE-Strip
polarizers were derived in terms of the Mueller sub-matrices
relating the relevant input and output Stokes parameters. As a
result, a dual-ridge layout, in which stepped-ridge discontinuities
are interleaved with grooved cavities, was selected. The heights of
both the stepped discontinuities and the grooved cavities were
considered as design degrees of freedom in order to minimize the
differential phase-error between the two principal polarizations of
the polarizer w.r.t. the ideal 90-deg value. The latter condition
is the one required for converting the incoming circular
polarizations into two linearly polarized ones. The polarizer
design allows for a complete manufacturing route (mechanical layout,
machining process and assembling) exhibiting high accuracy
(< 10 μm) for all the units. As a consequence, the measured
performance of the whole polarizer cluster is in tight agreement
with predictions. Notably, the in-band mean value of the spurious
conversion from the total intensity I to the two linearly
polarized Stokes parameters Q and U introduced by the polarizers
is smaller than -28 dB (mean value of fifty-one polarizers) with a
standard deviation less than 1 dB.
Mechanisms driving ESM-based marine ecosystem predictive skill on the east African coast
Authors: Jeon Woojin , Park Jong-Yeon , Stock Charles A , Dunne John P , Yang Xiaosong , Rosati Anthony 
Published: June 2022

Abstract
The extension of seasonal to interannual prediction of the physical climate system to include the marine ecosystem has a great potential to inform marine resource management strategies. Along the east coast of Africa, recent findings suggest that skillful Earth system model (ESM)-based chlorophyll predictions may enable anticipation of fisheries fluctuations. The mechanisms underlying skillful chlorophyll predictions, however, were not identified, eroding confidence in potential adaptive management steps. This study demonstrates that skillful chlorophyll predictions up to two years in advance arise from the successful simulation of westward-propagating off-equatorial Rossby waves in the Indian ocean. Upwelling associated with these waves supplies nutrients to the surface layer for the large coastal areas by generating north- and southward propagating waves at the east African coast. Further analysis shows that the off-equatorial Rossby wave is initially excited by wind stress forcing caused by El Niño/Southern Oscillation-Indian Ocean teleconnections.