bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tailoring childhood immunisation services in a socioeconomically disadvantaged community in New South Wales, Australia: a cost analysis
Authors: Thomas Susan , Williamson Kirsten , Ling Rod , Dolja-Gore Xenia , Islam Fakhrul M. , Higgins Helen , Durrheim David N. , Searles Andrew 
Published: October 2022

Background Using the World Health Organization’s ‘Guide to Tailoring Immunization Programmes’ (TIP), a three-step program was developed by health services in partnership with a marginalised community in New South Wales, Australia. The aim was to improve immunisation rates of 1-year-old children. For Step 1, nurses identified and monitored local children overdue for immunisation from a national register, and sent parents or family doctors reminders by mail or telephone. For Step 2, parents were offered appointments at a local health centre; and for Step 3, they were offered home visits. Methods An economic costing study was undertaken to examine the program’s resource use. Costs were collected between 1 June 2020 and 31 May 2021. Case records were obtained for 139 children. Results A total of 56 children became up to date after receiving TIP services; most after receiving Step 1 services (n = 37). Total annual costs (A$) for the program were $34 250 or $246 per case; or $612 per case becoming up to date. At $44 per case and $98 per case becoming up to date, Step 1B: personalised reminders, was the lowest costing step. Sensitivity analysis showed a possible 8% program savings through employment of nurses with a lower salary and use of video conference meetings. Conclusion This study provides information to the local health provider on the cost of TIP alongside their community-based programs. It also identified ways in which TIP could be made more cost-effective. Decision-makers can use this information to consider whether the investment in TIP is recommended.
Diurnal rhythms in testicular blood flow, testicular morphometry and reproductive hormones in Shiba goats
Authors: Samir Haney , Mandour Ahmed S. , Radwan Faten , Swelum Ayman A. , Yoshida Tomohiko , Tanaka Ryou , Nagaoka Kentaro , Watanabe Gen 
Published: October 2022

Context Testicular blood flow (TBF) is crucial for testicular function. The pattern of TBF in Shiba goats indicates seasonal variations. Aims This study aimed to investigate the effect of diurnal variations on TBF, testis volume (TV), testicular echogenicity, and reproductive hormones in goats over a 24-h period. Methods In three trials that went for three consecutive days each, 12 bucks were scanned using Triplex ultrasonography to assess the TV, pixel intensity of testicular echotexture (PIX), and Doppler indices of TBF (resistive index: RI and pulsatility index: PI) in four-time points a day (at 6.00, 12.00, 18.00, and 00.00 h). Concomitantly, the changes in circulating FSH, LH, inhibin, testosterone (T), estradiol (E2), cortisol, and melatonin were assessed. Key results Results revealed diurnal alterations in the calculated RI of TBF and the PIX of testicular parenchyma (P < 0.05). Lower RI values of the TBF were observed at 6.00 h compared to other time points. There were significant diurnal alterations in the levels of FSH (P < 0.05), LH (P < 0.05), T (P < 0.0001), E2 (P < 0.0001), cortisol (P < 0.0001), and melatonin (P < 0.0001). FSH attained a higher concentration at 18.00 h compared to 12.00 h. Concentrations of LH were significantly higher at 06.00 h compared to those at 18.00 h. Concentrations of T were significantly higher at 6.00 compared to other time points. E2 showed higher concentrations at 6.00 h and 00.00 h compared to 12.00 h and 18.00 h. On the contrary, concentrations of cortisol were significantly higher at 12.00 h and 18.00 h compared to 06.00 h and 00.00 h. The highest concentrations of melatonin were observed at 00.00 h compared to other time points, while the lowest concentrations were at 12.00 h. Conclusions Diurnal rhythm induces significant changes in TBF, testicular PIX, and circulating FSH, LH, T, E2, cortisol, and melatonin over the 24-h day. Implications The outcomes of the study are reflected in the advisability of monitoring the TBF at a fixed time a day to avoid the circadian rhythm effect.
Sonochemically synthesized mesoporous cobalt oxide nanoparticles for luminol-enhanced chemiluminescence sensing
Authors: Darbandi Masih , Alahmadi Maryam Sadat , Amjadi Mohammad , Hallaj Tooba 
Published: October 2022

Abstract
In recent years, mesoporous cobalt oxides have attracted more attention due to their exceptional physical and chemical properties and their important applications in various fields. The synthesis of cobalt oxides of various sizes, morphologies, and porosity is still a challenging process. In this report, mesoporous Co3O4 NPs with different porosity were synthesized through facile, one-step, and cost-effective routes, without using any complicated materials or instruments, via the sonochemical process. X-ray powder diffraction (XRD), BET, and transmission electron microscopy (TEM) were used to characterize the as-synthesized NPs. XRD technique was used to determine the crystal structure and phase of the NPs, BET to describe the porous nature of the NPs, and TEM to investigate the structure and morphology of the NPs. Next, the effect of as-synthesized Co3O4 NPs as a catalyst for the luminol-H2O2 chemiluminescence system was studied. Co3O4 NPs were chosen since they have nanoscale size, high specific surface area, and mesoporous nature. Therefore, these NPs can form more active sites and thus show unique catalytic activity than common ionic catalysts such as Co2+, Fe3+, Cu2+ used in the luminol-H2O2 CL system. Finally, this system was used to detect and measure H2O2 and glucose under optimal conditions. A good linear relationship was observed between the chemiluminescence intensity of the designed system and the concentration of H2O2 and glucose. A linear range like 0.25–10 pM for H2O2 and 1–30 nM for glucose was obtained. The excellent LOD of the proposed method for measuring H2O2 was about 0.07 pM, and for measuring glucose was about 0.14 nM.
Molecular dynamics simulations on the connectivity of topologically close-packed clusters in TiAl3 alloys
Authors: Gao Tinghong , Bian Zhetian , Gao Yue , Wang Bei , Liu Yutao , Xie Quan , Chen Qian , Xiao Qingquan , Liang Yongchao 
Published: October 2022

Abstract
Presently, there has been increasing attention on TiAl3, which is commonly used for fabricating power aviation devices owing to its good oxidation resistance and outstanding mechanical properties in high-temperature. As the microstructures determine the macroscopic properties of a material, we investigated the connectivity of icosahedral central atoms in TiAl3 using conventional methods in this study. The topologically close-packed (TCP) structures are present in supercooled liquids, metallic glasses, and metallic liquids. They are intrinsic to liquid metals and are an essential character of the structure in metallic glasses (MGs). However, because of the lack of the concept of connectivity of the TCP structures, we investigated connectivity from the icosahedral central atoms to TCP structures, and a formula was proposed to calculate the connectivity of the TCP structures. Based on the results, low temperatures and cooling rates are conducive to generate high connectivity between icosahedral central atoms and TCP structures. The proposed formula can characterize the connectivity of the TCP structures. These findings open new opportunities for conducting research on the connectivity of clusters in binary alloys.
Uncertainty evaluation in reference material characterization by double isotope dilution inductively coupled plasma mass spectrometry (ID-ICP-MS)
Authors: Lee Jong Wha 
Published: October 2022

Abstract
Double isotope dilution inductively coupled plasma mass spectrometry (ID-ICP-MS) is one of the most important measurement methods in the establishment of measurement standards for inorganic analysis. However, there is still no good consensus on approaches for uncertainty evaluation in double ID-ICP-MS. Particularly, approaches to treating the instrumental isotopic fractionation (IIF) phenomenon and correlation between uncertainty sources are diverse and often unclear in the literature. Here, an approach for uncertainty evaluation in double ID-ICP-MS measurements is described. Using three certified reference materials (CRMs), it is shown that the IIF effects cancel out and should not be included in the uncertainty budget. Further, a consistent way of considering correlated sources of uncertainty to prevent double counting of uncertainties is described in detail along with an example of measuring the mass fraction of magnesium in an oyster powder CRM.
Increasing risk from landfalling tropical cyclone-heatwave compound events to coastal and inland China
Authors: Wu Jie , Chen Yang , Liao Zhen , Gao Xuejie , Zhai Panmao , Hu Yamin 
Published: October 2022

Abstract
Tropical cyclones (TCs) and heatwaves are amongst the most deadly and costly natural hazards. Despite considerable advances in understanding each of them, their occurrences in rapid sequence (e.g. in a week) that introduce disproportionately large impacts to infrastructure and human health have received far less attention. Based on dynamical downscaling simulations, we project that currently rare landfalling TC-heatwave compound events would be five to ten times more frequent in coastal Southeast China, and migrate northward and westward to the intact interior. It is the substantial increase in heatwaves that contributes most to the projected increase in frequency and novel emergence of compound events. There would be higher fraction of severer compound events composed of either intense TCs (in the top 10% historically) or exceptional heatwaves (above the historical 99.9th percentile), with coastal Southeast China even bracing for out-of-ordinary combinations of the two. On top of the unprecedented frequency, intensity and land exposure, future emergence of unseasonal compound events in South and Southeast China would further overwhelm local adaptive capacities.
Intra and interspecific variability of Quercus suber and Quercus canariensis, an intrinsic water-use efficiency approach for differentiation
Authors: Frouja Olfa , Hammami Majdi , Dakhlaoui Sarra , Wannes Wissem Aidi , Hessini Kamel , Msaada Kamel , Ben Ahmed Hela 
Published: October 2022

Abstract
In Tunisia, the oak forest is essentially restricted to the north-west (Kroumirie and Mogods), which is the wettest zone of the country. It forms ecosystems of great ecological and socio-economic interest. This is a significant source of income for local population. In addition, it contributes to soil conservation and is home to a rich and diversified fauna and flora and offers the region a picturesque landscape. This precious and fragile forest capital is currently threatened under the effect of various pressures, mainly the browsing of young plants being reconstituted and vegetative competition regarding resources of the environment. Hence the interest in studying the intra and interspecific variability of the oak, this study is essentially based on the morphological and physiological comparison of the two species of oak, Quercus suber and Quercus canariensis with their cohabitation in the same area, this variability was carried out by multivariate biostatistical analyzes using a set of data including morphological traits, isotopic analysis of the leaves, water use efficiency, as well as the phenolic composition and antioxidant activities of the leaves extracts. The results showed that leaf morphology and water use efficiency are discriminating factors for differentiation to choose the right specie that will be used for reforestation. The Q. canariensis specie growing in the Bni Mtir region was characterized by a high intrinsic water-use efficiency and high biomass recovery. These results let us suppose that Q. canariensis was the perfect specie for reforestation given its ability to produce a large amount of biomass with less water, which is what environmentalists demand.
Additive-assisted defect passivation of perovskite with metformin hydrochloride: toward high-performance p-i-n perovskite solar cells
Authors: Huang Zhezhi , Fu Jianfei , Ji Wenxi , Zhang Longgui , Chen Qiaoyun , Zhang Zelong , Zhou Yi , Song Bo 
Published: October 2022

Abstract
Defects at the grain boundaries and surfaces of perovskite thin films are the key factors that cause nonradiative recombination, thus restricting the performance of perovskite solar cells (Pero-SCs). By introducing foreign additives to manage the chemical environment of the precursor, perovskite films can obtain optimized morphology and reduced defects, thereby enhancing the photovoltaic performance and stability of derived Pero-SCs. Herein, we report the bifunctional molecule metformin hydrochloride (MetHCl), whose multidentate structure is capable of simultaneously passivating several sorts of defects in perovskite films. Concurrently, the strong binding ability to Pb2+ makes it impressive in regulating perovskite crystallization. The nonvolatile MetHCl can remain in the perovskite film, contributing to acquiring a high-quality film with denser grains and fewer pinholes. Finally, p-i-n Pero-SCs containing the MetHCl additive exhibited enhanced stability and achieved a champion power conversion efficiency of 21.59% with an open-circuit voltage of 1.17 V.
Active Postlicensure Safety Surveillance for Recombinant Zoster Vaccine Using Electronic Health Record Data
Authors: Nelson Jennifer C , Ulloa-Pérez Ernesto , Yu Onchee , Cook Andrea J , Jackson Michael L , Belongia Edward A , Daley Matthew F , Harpaz Rafael , Kharbanda Elyse O , Klein Nicola P , Naleway Allison L , Tseng Hung-Fu , Weintraub Eric S , Duffy Jonathan , Yih W Katherine , Jackson Lisa A 
Published: October 2022

Abstract
Recombinant zoster vaccine (RZV) (Shingrix; GlaxoSmithKline, Brentford, United Kingdom) is an adjuvanted glycoprotein vaccine that was licensed in 2017 to prevent herpes zoster (shingles) and its complications in older adults. In this prospective, postlicensure Vaccine Safety Datalink study using electronic health records, we sequentially monitored a real-world population of adults aged ≥50 years who received care in multiple US Vaccine Safety Datalink health systems to identify potentially increased risks of 10 prespecified health outcomes, including stroke, anaphylaxis, and Guillain-Barré syndrome (GBS). Among 647,833 RZV doses administered from January 2018 through December 2019, we did not detect a sustained increased risk of any monitored outcome for RZV recipients relative to either historical (2013–2017) recipients of zoster vaccine live, a live attenuated virus vaccine (Zostavax; Merck & Co., Inc., Kenilworth, New Jersey), or contemporary non-RZV vaccine recipients who had an annual well-person visit during the 2018–2019 study period. We confirmed prelicensure trial findings of increased risks of systemic and local reactions following RZV. Our study provides additional reassurance about the overall safety of RZV. Despite a large sample, uncertainty remains regarding potential associations with GBS due to the limited number of confirmed GBS cases that were observed.
scSemiGAN: a single-cell semi-supervised annotation and dimensionality reduction framework based on generative adversarial network
Authors: Xu Zhongyuan , Luo Jiawei , Xiong Zehao 
Published: October 2022

Abstract

Motivation
Cell-type annotation plays a crucial role in single-cell RNA-seq (scRNA-seq) data analysis. As more and more well-annotated scRNA-seq reference data are publicly available, automatical label transference algorithms are gaining popularity over manual marker gene-based annotation methods. However, most existing methods fail to unify cell-type annotation with dimensionality reduction and are unable to generate deep latent representation from the perspective of data generation.

Results
In this article, we propose scSemiGAN, a single-cell semi-supervised cell-type annotation and dimensionality reduction framework based on a generative adversarial network, to overcome these challenges, modeling scRNA-seq data from the aspect of data generation. Our proposed scSemiGAN is capable of performing deep latent representation learning and cell-type label prediction simultaneously. Through extensive comparison with four state-of-the-art annotation methods on diverse simulated and real scRNA-seq datasets, scSemiGAN achieves competitive or superior performance in multiple downstream tasks including cell-type annotation, latent representation visualization, confounding factor removal and enrichment analysis.

Availability and implementation
The code and data of scSemiGAN are available on GitHub: https://github.com/rafa-nadal/scSemiGAN.

Supplementary information
Supplementary data are available at Bioinformatics online.
Mitotic exchange in female germline stem cells is the major source of Sex Ratio chromosome recombination in Drosophila pseudoobscura
Authors: Koury Spencer 
Published: October 2022

Abstract
Sex Ratio chromosomes in Drosophila pseudoobscura are selfish X chromosome variants associated with 3 nonoverlapping inversions. In the male germline, Sex Ratio chromosomes distort the segregation of X and Y chromosomes (99:1), thereby skewing progeny sex ratio. In the female germline, segregation of Sex Ratio chromosomes is mendelian (50:50), but nonoverlapping inversions strongly suppress recombination establishing a 26-Mb haplotype (constituting ∼20% of the haploid genome). Rare crossover events located between nonoverlapping inversions can disrupt this haplotype, and recombinants have sometimes been found in natural populations. We recently reported on the first lab-generated Sex Ratio recombinants occurring at a rate of 0.0012 crossovers per female meiosis. An improved experimental design presented here reveals that these recombination events were at least 4 times more frequent than previously estimated. Furthermore, recombination events were strongly clustered, indicating that the majority arose from mitotic exchange in female germline stem cells and not from meiotic crossing-over in primary oocytes. Finally, asymmetric recovery of complementary recombinants was consistent with unequal exchange causing the recombination-induced viability defects. Incorporating these experimental results into population models for Sex Ratio chromosome evolution provided a substantially better fit to natural population frequencies and allowed maintenance of the highly differentiated 26-Mb Sex Ratio haplotype without invoking strong epistatic selection. This study provides the first estimate of spontaneous mitotic exchange for naturally occurring chromosomes in Drosophila female germline stem cells, reveals a much higher Sex Ratio chromosome recombination rate, and develops a mathematical model that accurately predicts the rarity of recombinant Sex Ratio chromosomes in natural populations.
Associations between water insecurity and depression among refugee adolescents and youth in a humanitarian context in Uganda: cross-sectional survey findings
Authors: Logie Carmen H , Okumu Moses , Loutet Miranda , Berry Isha , Taing Lina , Lukone Simon Odong , Kisubi Nelson , Sokolovic Nina , Kyambadde Peter 
Published: October 2022

ABSTRACT

Background
Water insecurity is linked to poor mental health through intrapersonal, relational and community-based stressors. We examined water insecurity and depression among refugee youth in Bidi Bidi, Uganda.

Methods
We conducted a cross-sectional survey and multivariable ordinal logistic regression to examine associations between water insecurity and depression severity, adjusting for gender, resilience, social support and food insecurity.

Results
Among participants (n=115; mean age: 19.7 y, SD 2.3), 80.0% reported water insecurity and 18.3% had moderate/severe depression symptoms. Water insecurity was independently associated with higher levels of depression severity (adjusted OR: 5.61; 95% CI 1.20 to 26.30; p=0.03).

Conclusions
Findings suggest water insecurity was commonplace and associated with depression. Water insecurity could be integrated in refugee mental health promotion by policymakers and community-based programmers.
Supernova remnant W51C: optical and X-ray emission analysis
Authors: Reyes-Iturbide J , Ramírez-Ballinas I , Rosado M , Núñez D , Ambrocio-Cruz P , Arias L , Gabbasov R 
Published: October 2022

ABSTRACT
We present observations of the optical and X-ray emission from the Galactic supernova remnant W51C. From [S ii] Fabry–Pérot interferometry and H α and [S ii] images we detect filaments that are part of the optical counterpart of the supernova remnant. We obtain the kinematic distance to W51C, showing that it is one of the shortest distances reported in the literature. We also estimate other physical properties such as the velocity of the shock induced in the cloudlets emitted at optical wavelengths and the electron density of those cloudlets. From XMM–Newton observatory archival data, we obtain images of the diffuse X-ray emission of this supernova remnant. The spectrum of the X-ray emission is explored to estimate X-ray parameters such as luminosity and temperature of the hot plasma in the supernova remnant. We fit a thermal model with a plasma temperature of 1.4 keV for an X-ray thermal luminosity of 2.0 × 1036 erg s−1. With the parameters described above we test the model proposed by White & Long to explain the mixed morphology observed in W51C. We obtain an initial energy of the supernova explosion of 8.4 × 1050 erg and an age of 13 000 yr. The derived initial energy is typical of supernova remnants, but in disagreement with respect to older estimations that found higher values and suggested that W51C was the result of the explosion of two supernovae.
African-Centered Social Work in the 21st Century: A Content Analysis
Authors: Lateef Husain , Gale Adrian , Boyd Donte , Arab Hassan , Amoako Emmanuel , Williams Ed-Dee 
Published: October 2022

Abstract
Endorsement of African-centered theory and practice are widespread within Black communities across the United States. The usage of African-centered frameworks is also common among many Black social workers. However, past research suggests that African-centered theory and subsequent models of practice are marginalized within social work literature and curricula. Since advocacy began for the inclusion of African-centered approaches to practice during the mid to late 1990s, there have been no strategic analyses tracing how African-centered scholarship has advanced within social work. This study sought to examine to what extent the African-centered framework is included within scholarship among prominent social work journals. A content analysis was conducted of articles in six major social work journals published between 2000 and 2019. A total of 42 articles met the criteria for inclusion. While there has been a level of change in the number of published articles of African-centered social work, findings suggest that relative to other practice modalities/models, African-centered scholarship is noticeably lacking in social work literature. The article concludes with implications to advance culturally responsive research and practice with communities of African descent.