bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of inhaled nitric oxide in chronic obstructive pulmonary disease patients with hypercapnic respiratory failure and pulmonary hypertension
Authors: Struong Tuyet Thi , Shogenova L. V. , Selemir V. D. , Chuchalin A. G. 
Published: May 2022

Therapy with inhaled nitric oxide (iNO) in patients with hypercapnic respiratory failure (RF) and pulmonary arterial hypertension (PAH) is currently of scientific interest. The aim of this study was to evaluate the effects of iNO therapy on COPD patients with hypercapnic RF and PAH during exacerbation of the disease.Methods. A randomized, prospective, controlled trial included 30 patients with COPD (age 65 (62; 75) years) with hypercapnic RF and pulmonary arterial hypertension (PAH) treated at the State Budgetary City Teaching Hospital “City Clinical Hospital named after D.D.Pletnev of Healthcare Moscow City Department” (2021). The inclusion criteria were: PaCO2 ≥ 45 mm Hg and pulmonary artery systolic pressure PASP > 40 mm Hg as accessed by Doppler echocardiography. The patients were divided into two groups. Patients of the main group were administered iNO in the form of daily 90-minute sessons for two weeks using Tianoks device (Russian Federal Nuclear Center – All-Russian Research Institute of Experimental Physics, State Corporation “Rosatom”, Russia). Patients of the control group received treatment that corresponded to the severity of their COPD exacerbation according to the guidelines by Global Initiative for Chronic Obstructive Lung Disease (GOLD), 2020 – 2021. Hemodynamics and gas exchange, exercise tolerance, vascular stiffness, and obstructive disorders were assessed at baseline, on Days 7 and 14.Results. The main group demonstrated a decrease in PASP (38 (32; 43) mm Hg vs 47 (44; 54) mm Hg; p = 0.001), a decrease in stiffness index (SI) (7.03 m / s (5.3; 19.2) vs 12.2 m / s (5.7; 15.1); p = 0.01), decrease the pulmonary shunt fraction (Qs / Qt) (4.33% (3.7; 6.1) vs 9.12% (7.12; 11.3); p = 0.01), an increase in arterial vascular tone measured by reflective index (RI) (62.4% (51.2; 64.3) vs 58.5% (51.7; 63.8); p = 0.01), and increased exercise tolerance measured by 6-minute walking test (6MWT) (358.1 m (320.5; 368.2) vs 321.5 m (280.4; 329.1); p = 0.001) as compared to the control group.Conclusion. Our study indicates that iNO-therapy effectively reduces hypoxemia, endothelial dysfunction, improves hemodynamics, walking distance, and exercise tolerance during the exacerbation of COPD in patients with hypercapnic RF and PAH.
Ícones de educação e modernidade: Lyceu de Goiânia, Grupo Escolar Modelo e Instituto de Educação
Authors: Mahler Christine Ramos , Cardoso Bárbara Maria 
Published: May 2022

Este artigo trata de três edificações escolares pioneiras de Goiânia, dos pontos de vista historiográfico e arquitetônico: Lyceu de Goiânia (1937), Grupo Escolar Modelo – atual Colégio José Carlos de Almeida (1938) – e Instituto de Educação de Goiás (1946). A abordagem trata sobre a importância patrimonial (cultural) dessas edificações e dos seus respectivos valores, no contexto da construção da paisagem da capital planejada. A discussão acerca da modernidade se faz necessária para identificar parte da história da arquitetura educacional goianiense materializada nesses edifícios enquanto representações do futuro desejado por meio da educação como estratégia de desenvolvimento. Desse modo, o interesse é compreender as inovações que esses edifícios expressaram, em relação aos modelos escolares republicanos brasileiros por meio de suas espacialidades e linguagens. A análise dos projetos arquitetônicos permite inferir e revelar as intenções originais e mitos fundadores. Os aspectos programáticos e os paradigmas educacionais e culturais e sua localização no tecido urbano dão pistas sobre seu papel enquanto vetores do desenvolvimento da capital. Como contribuições pretendidas, espera-se dar visibilidade aos edifícios educacionais pioneiros, ícones do desenvolvimento da Marcha para o Oeste e aprofundar as críticas sobre a espacialidade da tipologia educacional e seu papel como espaço de transformação social e produção de conhecimento. Palavras-Chave: Arquitetura escolar, Patrimônio cultural, Modernidade; Escolas pioneiras; Goiânia.
Escribas semiletrados o iniciadores del castellano bilingüe andino: el caso del copista de Cristóbal de Molina
Authors: Cerrón-Palomino Rodolfo 
Published: May 2022

El presente artículo procura demostrar que una lectura atenta de la única copia del manuscrito de los Ritos y fábulas de los incas de Cristóbal de Molina pone en evidencia el castellano semiletrado que manejaba el copista de Molina—nos encontramos pues ante una copia adulterada del manuscrito original. Para ello, se discutirán cuatro puntos que sirven de soporte a la hipótesis planteada: los constantes vacíos en el curso del copiado, los tropiezos en la lectoescritura del castellano, las dificultades en la lectoescritura del quechua y las pruebas del “castellano motoso” del copista.
Effect of Sensory Properties, Shelf Life and Cost of Production on Black Gram (Vigna mungo) Flour Burfi
Authors: Patil S.P. , Narwade S.G. , Londhe G.K. , Patil R.A. 
Published: May 2022

Background: Among the traditional dairy products, burfi is the most popular khoa based confection in Indian subcontinent. Burfi has special importance in different functions like birthday, anniversary, wedding, etc. Consumers in India are becoming more health conscious and demand for healthier food because of rise in disposable income, educational level and awareness of nutrition. In wedding ceremony, now a days, besan burfi is famous instead of laddoos because of nutrition in pulses. Therefore, black gram can be also used in burfi due to it is rich in protein and having best results against many diseases in humans. Methods: Burfi was prepared from milk with constant level of sugar (30 per cent by weight of khoa) and different levels of black gram flour (2.5, 5, 7.5 and 10 per cent by weight of khoa). Properly blending khoa and sugar with black gram flour on low flame and then cut into pieces after setting. Result: The overall acceptability score for treatment T1, T2, T3, T4 and T5 were 8.27, 8.38, 8.51, 8.03 and 7.64 respectively. Burfi sample was evaluated for storage study conducted at room (30±2oC) temperature and refrigerated (7±2oC) temperature conditions. The cost of production of burfi with black gram powder was Rs. 255.38, Rs. 252.45, Rs. 249.62, Rs. 246.90 and Rs. 244.28 per kg for treatment T1, T2, T3, T4 and T5 respectively.
Bimbingan Teknis Penyusunan Bahan Ajar Biologi Berbasis Potensi Lokal pada MGMP Biologi SMA/MA Kabupaten Barito Kuala
Authors: Noorhidayati Noorhidayati , Putra Aminuddin Prahatama , Hardiansyah Hardiansyah , Mahrudin Mahrudin 
Published: May 2022

Kegiatan bimbingan teknis ini bertujuan memberi bekal dan bimbingan kepada guru-guru biologi sekolah menengah dalam menyusun bahan ajar berbasis potensi lokal. Pelaksanaan kegiatan menggunakan metode ceramah, diskusi, workshop, konsultasi daring, dan penugasan mandiri. Hasil kegiatan menunjukkan bahwa peserta menunjukkan antusiasme yang tinggi, sebagaimana terlihat dari proses tanya jawab dan diskusi yang berlangsung sangat dinamis. Banyak peserta yang menyampaikan potensi lokal daerah, serta meminta saran dan masukan terkait bahan ajar apa yang dapat dikembangkan. Berdasarkan data yang masuk, terdapat 33 orang guru (82,25%) dari 40 peserta yang sudah mengirimkan format yang berbentuk draft pengembangan bahan ajar. Hal ini menunjukkan peserta telah mendapatkan bekal pengetahuan dan memiliki motivasi sangat tinggi untuk mengembangkan bahan ajar berbasis potensi lokal. Untuk kegiatan serupa ke depannya agar dapat menjadi lebih baik lagi sebaiknya dilaksanakan bimbingan berkelanjutan. This technical guidance activity aims to provide provision and guidance to high school biology teachers in preparing teaching materials based on local potential. Implementation of activities using lecture methods, discussions, workshops, online consultations, and independent assignments. The activity results showed that the participants showed high enthusiasm, as seen from the very dynamic question and answer process and discussion. Many participants conveyed the local potential of the region and asked for suggestions and input regarding what teaching materials could be developed. Based on the incoming data, there are 33 teachers (82.25%) of the 40 participants who have sent a format in the form of a draft of the development of teaching materials. This shows that the participants have acquired knowledge and have very high motivation to develop teaching materials based on local potential. For similar activities in the future to be even better, continuous guidance should be carried out.
The Sources of the Formation of Bibliographic Repertoire of Russian Language Books Published Abroad (1927–1991)
Authors: Nosov N. N. 
Published: May 2022

The aim of the article is to reveal foreign Russian language publications as the main sources of the formation of the bibliographic repertoire of books in Russian published abroad, reflected in the bibliographic database «Books published in Russian abroad, 1927–1991», compiled by the staff of Research department of bibliography of Russian State Library. The specific features of the database and special cases associated with the requirements for the repertoire of the publications included in the database are characterized. Information on auxiliary indexes adjacent to the database, reflecting that of about the persons involved in book publications, keywords, geographic names and the names of organizations associated with publications is given. The main sources are outlined, within the framework of which the selection of the bibliographic repertoire corresponding to the topic of the main database is carried out: 1) editions of the Russian emigration circles in different countries; 2) editions of the socialist countries; 3) foreign editions. Each of the sources is considered and characterized, the specifics of the ways of organizing the publishing process, depending on each of them, are highlighted. Based on the requirements of the maximum possible practical verification of the material covered by the database de visu, the author considers the specifics of the search and analysis of the material, depending on a source of the bibliographic repertoire formation. The variety of bibliographic resources dictated by such specifics is noted, the variety of ways of referring to them by a bibliographer in his practical search and reflection of bibliographic material in the database.The fundamental differences between the considered sources are highlighted. There are raised questions related to the quantitative ratio within the database of publications corresponding to the indicated sources of its formation.
Emotional security as a condition for preventing fear of terrorism
Authors: Chernykh S. I. 
Published: May 2022

Introduction. Terrorophobia is today one of those fears that are commonly called global. The fear of terrorism as a real threat to private life becomes social and not every government is able to prevent terrorist attacks committed on its territory.Purpose setting. Prevention of the emergence and development of terrorophobia is, coming from society and the individual himself, a specific barrier to the fear of terrorism as an action and a social phenomenon as a whole. We believe that the main factor contributing to the overcoming of terrorophobia coming from society is educational activities. A factor coming from the individual (family) upbringing and self-education. The purpose of these three processes is one – the emotional protection of the individual from fears of different qualitative certainty. Analysis of emotional security as a factor in the prevention of terrorophobia.Methodology and methods of the study. The theoretical and methodological basis of the study was made up of the main provisions of the subject-activity, system and functional approaches developed by domestic and foreign scientists.Results. The article proclaims the thesis that the emotional security of the subject, formed and developed at the personal level, is the most important condition (along with many others) of prevention and "experiencing" both the threat of terrorism itself and the terrorist attack itself as an action, a witness (and even a victim ) which any individual can become. Educational potential is a factor contributing to an increase in emotional security through psychological readiness, extensive communications and the improvement of one’s intellectual level.Conclusion. The goal of emotional security is always twofold: overcoming fears of any etiology and conscious reflection on the impossibility of their absolute overcoming. In the extreme, the goal is to teach yourself to live in conditions of uncertainty.
Existential-reflexive strategy of didactic communication: psychological explication
Authors: Menshikov P. V. , Arpentieva M. R. 
Published: May 2022

Introduction. Psychologically competently and accurately organized and implemented didactic communication between the student and the teacher is one of the leading conditions for the success of education and upbringing.Problem statement. The existing set of methods, technologies, principles, models of didactic communication sometimes describes completely different strategies for its construction and implementation. The requirements and basic postulates of different strategies can not only differ significantly, but also directly contradict each other. The strategies themselves can be applicable and effective in a certain range of educational situations, which must be taken into account in order to successfully build didactic interaction with students. The purpose of the study is an attempt to systematize the ideas about the strategies of didactic communication with students, who, with varying degrees of effectiveness, use teachers in the practice of current educational interaction.Methodology of the study. As a basis for a comparative analysis of various strategies of didactic communication, the authors propose the key construct in the views of the teacher, spatial and temporal modes of communication, the "concept of teaching influence", the image of the student in the views of the teacher, typical communicative means, the organizational form of didactic communication reproduced by the teacher, communicative self-identification of the educator, reflection or methods of research and correction of didactic communication.Results. In the process of comparative analysis, the authors characterize the psychotechnical, consultative-psychotherapeutic and existential-reflexive strategies of didactic communication.Conclusion. It is concluded that in the real practice of educational interaction, the above strategies can be represented by numerous variations, partially intersecting and interpenetrating. However, the creation of conditions for a motivated and conscious choice by the teacher of a didactic communication strategy that, on the one hand, would meet didactic goals, and on the other hand, would correspond to his/her communicative attitudes and system of ideas, is an urgent task of the educational process. This is where educational psychology can and should help.
Psychological problems of the formation of a common value system: conceptualization of social functions of the Russian military intelligentsia
Authors: Naumov P. Yu. 
Published: May 2022

Introduction. The subject of research in the article is the psychological problems of the formation of a system of universal values.Purpose setting. The paper conceptualizes the social functions of the Russian military intelligentsia. It is noted that at present humanity is experiencing a crisis of traditional and classical forms and methods of sociality, starting with the family and ending with the state and the world community.Methodology of the study. The main methods in the work were the system method; historiographical method; comparison and modeling.Results. The lack of fairness and honesty is the main cause of economic and social disruption, which is rapidly progressing. It can be stopped only through the restoration of attention to the common, the creation and cultivation of universal values. Without belittling the importance and significance of local communities, it is necessary to create a common value space. An important condition for this is the agreement on basic values. The author points out that in the most difficult socio-cultural and informational conditions, the system of professional military education and upbringing is faced with the task of forming and developing the personality of a professional military officer, i.e. an officer who possesses not only professional qualities and abilities, knowledge and skills that form his competence, but also a system of values that characterizes him as a defender of the Motherland and an intellectual.Conclusion. As a conclusion, it is substantiated that a universal, humanistically oriented identity based on common moral values can be “cemented” by the intelligentsia, which needs to become a social pillar of justice and solidarity as the highest forms of social community. It is logical that the value system of the intelligentsia will be intelligence as a social existential quality, focused on common moral values, and not just on the professional ethics of particular social groups. At the same time, since the system of military education has remained a kind of “enclave” of the traditional education system, in which the processes of training and education perform an equally important function, it is the military intelligentsia that is able to take on the role of supporting for the rest of the social groups that are traditionally considered to be intellectuals.
Critical thinking and its necessity for the system of higher education
Authors: Barbashina E. V. 
Published: May 2022

Introduction. In modern literature on philosophy, pedagogy, psychology, the need for critical thinking for a person living in modern society, and for a graduate of a higher educational institution, is affirmed.Problem statement. The purpose of the article is to specify the reasons for the need for critical thinking. To achieve the goal at the first stage, the author analyzed the English-language review articles on various aspects of critical thinking.Methodology of the study. At the second step, based on the results of the first one, the most significant features of understanding critical thinking in philosophy (ideal, abstract carrier of critical thinking, emphasis on formal logical thought procedures), psychology (attention to thinking in specific situations, determining the connection between critical thinking and types of behavior, analysis of critical thinking skills in certain situations), pedagogy (orientation to the educational practice , reliance on empirical research).Outcomes. Based on the analysis of the review articles, the most significant coherent characteristics of critical thinking as a process were identified: the ability to fix a problem and to put forward hypotheses for its solution, reasoned analysis of hypotheses, comparison with other options, ability to refuse a preliminary solution to the problem, and others. It was also revealed that “intellectual virtues” are necessary for the implementation of critical thinking: the desire for education, responsible reasoning, mental flexibility, rejection of prejudices and intellectual egocentrism.Findings. The analysis of the documents of the World Economic Forum (2016, 2018) showed that critical thinking is included in the list of the main skills of students and professionals.
Low Alveolar Macrophage Function, Low IL-6, and High CD4 Cell Count Interaction in BALF of Severe Pneumonia Patients with Extubation Success
Authors: Singh Gurmeet , Rumende Cleopas Martin , Sharma Surendra K , Rengganis Iris , Amin Zulkifli , Loho Tonny , Pranggono Emmy Hermiyanti , Harimurti Kuntjoro , Wibowo Heri , Fauzi Nova Bornida , Masse Sudirman Fakhruddin 
Published: May 2022

Abstract
BackgroundUnderstanding the bronchoalveolar-lavage fluid immunopathology biomarker interactions can help clinicians decipher the pathophysiology of severe pneumonia and get better management for early extubation.ObjectivesThe objectives were to assess bronchoalveolar lavage fluid biomarker interactions of severely affected lung and their association in determining the early extubation success.MethodsIn this cross-sectional study, we consecutively evaluated 137 severe pneumonia patients. Patients who fulfilled inclusion criteria will undergo early bronchoscopy. The BALF was collected from the right and left lungs. Two Respirologist and Critical Illness consultants, plus one internist, determined the location for severely affected lung. Biomarker interactions in severely affected lung were analyzed. The primary outcome was the 19-days extubation.ResultsForty patients underwent bronchoscopy for BALF collection. The right lung was the predominant severely affected lung (28 patients). Eight patients survived and were successfully extubated within 19 days. There were significantly higher absolute CD4 + BALF cell counts (95% Confidence Interval = 9,24–49,50, p = 0,003) in the left lung and higher absolute CD4 + BALF cell counts (95% Confidence Interval = 9,00–29,75, p = 0,010) in the patients with extubation success and survived. Among all the patients with extubation success within 19 days, eight patients (100%) displayed the tendency of high CD4 levels (cutoff points median 16 cells/µL), low expression of alveolar macrophage function (cutoff points by ROC 756.5 MFI CD169), and low expression of IL-6 (cutoff points by ROC 369 pg/mg protein).ConclusionIn severely affected lung of severe pneumonia patients with early extubation success and survived, we found biomarker interactions marked by low alveolar macrophage function, low IL-6 levels, and high CD4 levels.Trial RegistrationThe study was registered at UMIN Clinical Trials Registry (UMIN-CTR) (registration number UMIN000046236), accessible at: https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000049197