bluuebunny/crossref_metadata_2025_split huggingface dataset:
Designing Low‐Concentration Propylene Carbonate‐based Electrolyte by Manipulating Lithium+‐Solvation Structure for Graphite Anode
Authors: Guan Dichang , Hu Guorong , Peng Zhongdong , Cao Yanbing , Gan Zhanggen , Zhang Xudong , Du Ke 
Published: July 2022

AbstractWe systematically study the correlation between Li+‐solvation structure, interfacial stability, and electrochemical behavior in the system of graphite anode with low‐concentration (0.5 M) propylene carbonate (PC)‐based electrolyte (LCPE). 1,1,2,2‐tetrafluoroethyl‐2,2,3,3‐tetrafluoropropylether (TTE) [or 1,1,2,2‐tetrafluoroethyl‐2,2,2‐trifluoroethyl ether (HFE)] is used to manipulate the solvation structures of Li+ in the LCPEs. Varying Li+‐solvation structures are realized by changing the volume ratios of PC to TTE (or HFE) in the LCPEs. With the increase of TTE (or HFE) dosages, the relative contents of LiF and LixPOyFz in SEI derived from
increase, while the decomposition products of PC reduce. With enough TTE (or HFE) in the LCPE, the Li||graphite cell exhibits reversible (de)lithiation without PC co‐intercalation and continuous electrolyte decomposition due to the shield of a compact SEI rich in LiF and LixPOyFz. Our work proves it is practicable to achieve LiF‐riched SEIs on graphite anodes and realize reversible (de)lithiation in LCPEs by regulating the Li+‐solvation structures with inert cosolvents.
Cover Picture: Enantioselective halogenation via asymmetric phase‐transfer catalysis (BKCS 07/2022)
Authors: Lee Sunggi , Chung Won‐jin 
Published: July 2022

Chiral phase‐transfer catalyst brings insoluble ionic halogenating reagents into the solution and mediates enantioselective halogenations by forming highly ordered asymmetric environments through ion pairing and/or hydrogen‐bonding interactions with the substrate and the reagent. Such approaches have been enormously successful in both nucleophilic and electrophilic halogenations. In this review, the remarkable examples over the past decade are surveyed with brief mechanistic discussions.
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How commuting time influences hedonic consumption: The role of perceived stress
Authors: Huang Minxue , Zhan Mengmeng , Huang Ruyao , Wu Jingjing 
Published: July 2022

AbstractThe commuting cost has increased inevitably under the background of industrialization and urbanization, which has vital impacts on daily life. In this paper, we implement an empirical study to explore the impact of commuting time on hedonic consumption and the underline mechanism of perceived stress based on the data of CFPS 2014 (a national social tracking survey project). The Tobit regression combined with the Heckman two‐stage model is applied to correct the sample selection bias. The results show that the increase in commuting time will aggrandize residents' tendency and expenditure of hedonic consumption. Moreover, we conduct situational experiments as a supplement to verify the main effect and mediation mechanism to exclude alternative explanations. The mechanism analyses prove that the perceived stress caused by long commuting time is a possible mediator for hedonic consumption. This study enriches the relative studies on social influences of commute, especially proving that this social issue may provide some benefits for business practice.
Association of autosomal‐recessive‐type distal renal tubular acidosis and Glanzmann thrombasthenia as a consequence of runs of homozygosity
Authors: Aso Keiko , Soutome Takehiko , Satoh Mari , Aoki Takako , Ogura Hiromi , Yamamoto Toshiyuki , Kanno Hitoshi , Takahashi Hiroyuki 
Published: July 2022

AbstractWe report the case of a Filipino girl with autosomal‐recessive‐type distal renal tubular acidosis and Glanzmann thrombasthenia caused by homozygous variants in the genes SLC4A1 and ITGA2B within the long homozygous DNA region on chromosome 17q21.31. This haplotype may be retained among individuals of Filipino descent.
A visualized pulmonary arterial thrombus by using a modified echocardiographic view in an intermediate‐risk acute pulmonary embolism patient: A case report
Authors: Mu Guanyu , Li Feixue , Chen Xiaolin , Zhao Bo , Li Guangping , Fu Huaying 
Published: July 2022

AbstractAcute pulmonary embolism (APE) is a life‐threatening disease with nonspecific clinical signs and symptoms. Rapid and accurate diagnosis is crucial for the clinical management of patients with acute pulmonary embolism. A recommended echocardiography view may be of further help in the diagnosis and evaluation of the change in thrombosis and treatment. We reported a case of a 74‐year‐old man with a 12‐day history of decreased exercise capacity and dyspnea. The patient was diagnosed with intermediate‐risk APE as several pulmonary emboli in pulmonary artery were seen in multidetector computed tomographic pulmonary angiography with normal blood pressure and echocardiographic right ventricular overload. And we found a pulmonary artery clot in the right pulmonary artery through transthoracic echocardiography. After 11‐days anticoagulation, the patient underwent a reassessment, showed a decrease in RV diameter and pulmonary artery thrombus. This case highlights the significant role that echocardiography played in a patient who presented pulmonary embolism with a stable hemodynamic situation and normal blood pressure. The modified echocardiographic view could provide correct diagnosis by identifying the clot size and location visually. Knowledge of the echocardiography results of APE would aid the diagnosis.
Fabrication and Properties of n‐Octadecane/Nano‐MgO/Expanded Graphite as a Thermal Storage Material
Authors: Wei Yuchen , Wang Wenze , Fang Guiyin 
Published: July 2022

AbstractComposite thermal storage materials (CTSM) composed of n‐octadecane, nano‐MgO, and expanded graphite (EG) were fabricated. Fourier transform infrared spectroscopy and X‐ray diffractometry results confirm that the CTSM components were combined in physical interaction. Scanning electronic microscopy images illustrate the CTSM microstructure. The differential scanning calorimetry results indicate that the melting temperature and latent heat of CTSM3 are 28.31 °C and 195.06 kJ kg−1, respectively, and the solidifying temperature and latent heat are 27.69 °C and 191.86 kJ kg−1, respectively Thermogravimetric analysis proves that CTSM3 has good thermal stability. The heat conductivity of CTSM3 is 3.59 times that of n‐octadecane/nano‐MgO. Thermal cycle experiments verify that the chemical structure of CTSM3 is stable.
Comparative Study on Chitosans as Green Binder Materials for LiMn2O4 Positive Electrodes in Lithium Ion Batteries
Authors: Künne Sven , Püttmann Frederik , Linhorst Max , Moerschbacher Bruno M. , Winter Martin , Li Jie , Placke Tobias 
Published: July 2022

AbstractThe increasing demand for lithium ion batteries consequently involves research on environmentally benign materials and processing routes. Environmentally friendly cobalt‐free, and fluorine‐free electrodes processed without organic solvents were targeted as this approach combines high work safety and sustainability with good electrochemical performance. In this study, chitosan‐based biopolymers were synthesized and systematically investigated for the first time as “green” binders for positive electrodes utilizing LiMn2O4 (LMO). In particular, chitosans with different specifically designed low and high degrees of polymerization (DP), each with comparable degree of acetylation (DA), revealed insights into the impact on the mechanical and electrochemical performance of LMO positive electrodes. Herein, low DP chitosan provided twice the adhesion strength compared to the state‐of‐the‐art binder polyvinylidene difluoride (PVdF) in LMO electrodes, thus, showing the opportunity to reduce the binder content and increase the specific energy. Electrodes with DA<16 % chitosan‐based binder could deliver higher discharge capacities than cathodes using PVdF or chitosans with DA>16 % in LMO||Li metal cells. Cross‐linking of chitosans with citric acid (CA) was demonstrated to significantly increase the discharge capacity up to 80 mAh g−1 at 10 C charge/discharge rate.
Evaluation of p16/Ki‐67 dual‐stain as triage test for high‐risk HPV‐positive women: A hospital‐based cross‐sectional study
Authors: Chen Xiaoyan , Chen Chen , Liu Liyi , Dai Wenjun , Zhang Jing , Han Chunyan , Zhou Shujun 
Published: July 2022

BackgroundMost human papillomavirus (HPV)‐positive women recover from infections and do not develop cervical intraepithelial neoplasia (CIN) and cervical cancer. Additional triage approaches are needed to reduce unnecessary colposcopy referrals. The aim of this study is to determine the high‐risk HPV prevalence in a hospital‐based population and to evaluate the performance of p16/Ki‐67 dual‐stain test for the triage of high‐risk HPV‐positive women to detect precursor lesions and cervical cancer compared with the ThinPrep cytologic test (TCT).MethodsIn a hospital‐based population, 100,801 women were provided with a primary HPV DNA test and only women with high‐risk HPV infections were triaged using TCT and p16/Ki‐67 dual‐stain test. CIN2 or worse (≥CIN2) or CIN3 or worse (≥CIN3) were defined as the clinical end points.ResultsThe p16/Ki‐67 dual‐stain indicated a statistically significant higher sensitivity (82.8% vs. 66.7%%), specificity (51.6% vs. 44.4%), positive predictive value (33.2% vs. 25.8%), negative predictive value (91.2% vs. 82.1%), and accuracy (58.6% vs. 49.4%) compared with TCT examination within ≥CIN2 cases. Similar patterns were observed for the ≥CIN3 end point.ConclusionsOur study demonstrated that p16/Ki‐67 dual‐stain test could achieve better performance compared with TCT examination for ≥CIN2 or ≥ CIN3 detection, representing a promising approach as a specific and efficient triage strategy for high‐risk HPV‐positive women.
The influence of exercise on clinical pain and pain mechanisms in patients with subacromial pain syndrome
Authors: Lyng Kristian Damgaard , Andersen Jonas Dahl , Jensen Steen Lund , Olesen Jens Lykkegaard , Arendt‐Nielsen Lars , Madsen Niels Kragh , Petersen Kristian Kjær 
Published: July 2022

AbstractBackgroundFew studies have investigated the underlying mechanisms for unilateral subacromial pain syndrome (SAPS). Therefore, this study examined (1) if 8‐weeks of exercise could modulate clinical pain or temporal summation of pain (TSP), conditioned pain modulation (CPM), and exercise‐induced hypoalgesia (EIH) and (2) if any of these parameters could predict the effect of 8‐weeks of exercise in patients with unilateral SAPS.MethodsThirty‐seven patients completed a progressive abduction exercise program every other day for 8‐weeks. Worst shoulder pain in full abduction was rated on a numeric rating scale (NRS). Pain pressure thresholds (PPTs), TSP, CPM, EIH, Shoulder Pain and Disability Index (SPADI), Pain Catastrophizing Scale (PCS), PainDETECT questionnaire (PD‐Q), Pain Self‐Efficacy Questionnaire (PSE‐Q) and Pittsburgh Sleep Quality Index (PSQI) were assessed before and after intervention.ResultsThe intervention improved worst pain intensity (p < 0.001), increased the CPM (p < 0.001), improved the sleep scores (p < 0.005) and reduced the PainDETECT ratings (p < 0.001). No changes were observed in PPT, TSP, EIH, SPADI, PCS and PSE‐Q (all p > 0.05). In a linear regression, the combination of all baseline parameters predicted 23.2% variance in absolute change in pain after 8 weeks. Applying backwards elimination to the linear regression yielded that baseline pain intensity combined with TSP predicted 33.8% variance.ConclusionThis explorative study suggested reduction in pain, improved sleep quality and increased CPM after 8‐weeks of exercise. Furthermore, the results suggests that low pain intensity and high TSP scores (indicative for pain sensitisation) may predict a lack of pain improvement after exercise.
From ion‐sensitive field‐effect transistor to 2D materials field‐effect‐transistor biosensors
Authors: Rizzato Silvia , Monteduro Anna Grazia , Leo Angelo , Todaro Maria Teresa , Maruccio Giuseppe 
Published: July 2022

AbstractField‐effect transistors have strong applications in biosensing field from pH and glucose monitoring to genomics, proteomics, cell signaling assays, and biomedical diagnostics in general. Notable advantages are the high sensitivity (thanks to intrinsic amplification), quick response (useful for real‐time monitoring), suitability for miniaturization, and compact portable read‐out systems. The initial concept of ion‐sensitive field‐effect transistors evolved with the emergence of novel classes of materials beyond traditional semiconductors. Recently, 2D nanomaterials are redesigning the field providing superior performances with large surface‐to‐volume ratio, high carrier mobility, more effective local gating, high transconductance, and operation at low voltages. Here, after a brief conceptual introduction, we review progresses and perspectives of 2D materials field‐effect‐transistor biosensors with special focus on opportunities, most recent applications, present challenges, and future perspectives.
A worldwide survey on the use of animal‐derived materials and reagents in scientific experimentation
Authors: Cassotta Manuela , Bartnicka Joanna Julia , Pistollato Francesca , Parvatam Surat , Weber Tilo , D'Alessandro Vito , Bastos Luisa Ferreira , Coecke Sandra 
Published: July 2022

AbstractThe use of cell and tissue‐based methods in basic, applied and regulatory science has been increasing exponentially. Animal‐derived components, including serum, coating materials, growth factors and antibodies are routinely used in cell/tissue cultures and in general laboratory practices. In addition to ethical issues, the use and production of animal‐derived materials and reagents raises many scientific concerns, generally associated with presence of undefined components and batch‐to‐batch variability, which may compromise experimental reproducibility. On the other hand, non‐animal materials and reagents, such as human cells, alternatives to animal sera or non‐animal recombinant antibodies, are becoming increasingly available, and their use is encouraged by the EU Directive 2010/63 and the Guidance Document on Good In vitro Method Practices (GIVIMP), published by the Organization for Economic Cooperation and Development (OECD). In an effort to map the current state of use of animal‐derived reagents across different sectors and to identify the obstacles possibly hampering the implementation of non‐animal derived alternatives, a global online survey addressed to scientists working on in vivo, in vitro, in silico methods, in academia as well as pharmaceutical or cosmetic companies, was conducted with the goal to understand: 1) the most commonly used animal‐derived materials and reagents, 2) the main issues associated with the production and use of animal‐derived materials and reagents, 3) the current level of knowledge on available non‐animal alternative materials and reagents, and 4) what educational and information sources could be most useful or impactful to disseminate knowledge on non‐animal alternatives. This paper provides an overview of the survey replies and discusses possible proposals to increase awareness, acceptance and use of non‐animal ingredients.
Cargas Coming down: Chronic stress, Chicana‐Indigenous spiritual healing, and feminist fugitive potentiality
Authors: Raschig Megan 
Published: July 2022

AbstractThe bodies of low‐income Chicana‐Indigenous women are often sites of chronic racialized and gendered stress, as well as tremendous potentiality. I examine the relationship between stress and possibility as shaped by Chicana‐Indigenous spiritual healing among members of a women's healing collective in California. These women articulate chronic stresses as cargas, Spanish for burden, baggage, or charge. Unloading these stresses among each other, or descargando, leads to actions mobilized as anticarceral activism. Attention to their sense of stress carried collectively as cargas builds on Black feminist understandings of stress as structured by racialized criminalization and state and carceral violence while illuminating the materiality and potentiality of this embodiment in Chicana‐Indigenous contexts. The strategies cultivated for healing in these conditions underscore that stress is a worldly phenomenon, requiring emergent coalitions addressing social and structural conditions rather than solely individual therapeutic remedy or resilience. Working from feminist and fugitive anthropological commitments, centering descargando as an embodied knowledge praxis, I argue that an anthropological concern with potentiality must have an active, liberatory ethics, rooted in intersectional solidarity, accountability, and care.
Microglia deficiency accelerates prion disease but does not enhance prion accumulation in the brain
Authors: Bradford Barry M. , McGuire Lynne I. , Hume David A. , Pridans Clare , Mabbott Neil A. 
Published: July 2022

AbstractPrion diseases are transmissible, neurodegenerative disorders associated with misfolding of the prion protein. Previous studies show that reduction of microglia accelerates central nervous system (CNS) prion disease and increases the accumulation of prions in the brain, suggesting that microglia provide neuroprotection by phagocytosing and destroying prions. In Csf1rΔFIRE mice, the deletion of an enhancer within Csf1r specifically blocks microglia development, however, their brains develop normally and show none of the deficits reported in other microglia‐deficient models. Csf1rΔFIRE mice were used as a refined model in which to study the impact of microglia‐deficiency on CNS prion disease. Although Csf1rΔFIRE mice succumbed to CNS prion disease much earlier than wild‐type mice, the accumulation of prions in their brains was reduced. Instead, astrocytes displayed earlier, non‐polarized reactive activation with enhanced phagocytosis of neuronal contents and unfolded protein responses. Our data suggest that rather than simply phagocytosing and destroying prions, the microglia instead provide host‐protection during CNS prion disease and restrict the harmful activities of reactive astrocytes.
Preoperative function‐specific connectome analysis predicts surgery‐related aphasia after glioma resection
Authors: Ille Sebastian , Zhang Haosu , Sogerer Lisa , Schwendner Maximilian , Schöder Axel , Meyer Bernhard , Wiestler Benedikt , Krieg Sandro M. 
Published: July 2022

AbstractGlioma resection within language‐eloquent regions poses a high risk of surgery‐related aphasia (SRA). Preoperative functional mapping by navigated transcranial magnetic stimulation (nTMS) combined with diffusion tensor imaging (DTI) is increasingly used to localize cortical and subcortical language‐eloquent areas. This study enrolled 60 nonaphasic patients with left hemispheric perisylvian gliomas to investigate the prediction of SRA based on function‐specific connectome network properties under different fractional anisotropy (FA) thresholds. Moreover, we applied a machine learning model for training and cross‐validation to predict SRA based on preoperative connectome parameters. Preoperative connectome analysis helps predict SRA development with an accuracy of 73.3% and sensitivity of 78.3%. The current study provides a new perspective of combining nTMS and function‐specific connectome analysis applied in a machine learning model to investigate language in neurooncological patients and promises to advance our understanding of the intricate networks.
How do thermal conditions in intensive care units affect the health and well‐being of intensivists?
Authors: Vieira Elamara Marama de Araujo , Silva Jonhatan Magno Norte da , Silva Luiz Bueno da , Nascimento João Agnaldo do , Leite Wilza Karla dos Santos , Bispo Lucas Gomes Miranda 
Published: July 2022

AbstractThis study presents situational risk scenarios to predict the potential implications of predicted and perceived thermal configurations on the health and well‐being of health care professionals in intensive care units (ICUs). Nine ICUs were selected, and thermal variables were collected; simultaneously, 128 health care professionals were interviewed to assess their perceptions, satisfaction, and health conditions related to their workplace environment. In scenarios with thermal comfort (either predicted or perceived), the risk of exposure to physical and psychological symptoms was reduced. This effect also extends to predictions and perceptions tending toward slightly cooler temperatures. In situations with a predicted mean vote below −1.5 and above 0.5, symptom complaints increased, even when the health care professionals perceived their environment as thermally comfortable, with the most extreme cases generating an increase of up to 27% in the baseline probability. Adjusting the workplace environment to be thermally comfortable can reduce symptom complaints.
Does individual educational attainment affect educational homogamy?—Evidence from CGSS
Authors: Huo Congjia , Chen Lingming 
Published: July 2022

AbstractFamily is the basic unit that constitutes social relations, and marriage‐matching determines the development trajectory of a household. Education has become one of the most important ingredients of marriage in modern society, and the proportion of homogamy is increasing day by day. This article employs the data from the Chinese General Social Survey to research the mechanism of educational attainment on the educational homogamy. To eliminate the effect of endogeneity, we use the Probit model and instrumental variables for testing. The empirical results indicate that social members with higher educational backgrounds are more likely to choose educational homogamy. After controlling for other variables, social members and female members with lower ages are more likely to choose spouses with similar educational backgrounds.
Compatibility and function of human induced pluripotent stem cell derived cardiomyocytes on an electrospun nanofibrous scaffold, generated from an ionomeric polyurethane composite
Authors: Chen Yizhou , Chan Jennifer P. Y. , Wu Jun , Li Ren‐Ke , Santerre J. Paul 
Published: July 2022

AbstractSynthetic scaffolds are needed for generating organized neo‐myocardium constructs to promote functional tissue repair. This study investigated the biocompatibility of an elastomeric electrospun degradable polar/hydrophobic/ionic polyurethane (D‐PHI) composite scaffold with human‐induced pluripotent stem cell‐derived cardiomyocytes (hiPSC‐CMs). The composite material was electrospun to generate scaffolds, with nanofibres oriented in aligned or random directions. These features enabled the authors to evaluate the effect of characteristic elements which mimic that of the native extracellular matrix (alignment, chemical heterogeneity, and fiber topography) on hiPSC‐CMs activity. The functional nature of the hiPSC‐CM cultured on gelatin and Matrigel‐coated scaffolds were assessed, investigating the influence of protein interactions with the synthetic substrate on subsequent cell phenotype. After 7 days of culture, high hiPSC‐CM viability was observed on the scaffolds. The cells on the aligned scaffold were elongated and demonstrated aligned sarcomeres that oriented parallel to the direction of the fibers, while the cells on random scaffolds and a tissue culture polystyrene (TCPS) control did not exhibit such an organized morphology. The hiPSC‐CMs cultured on the scaffolds and TCPS expressed similar levels of cardiac troponin‐T, but there was a higher expression of ventricular myosin light chain‐2 on the D‐PHI composite scaffolds versus TCPS, indicating a higher proportion of hiPSC‐CM exhibiting a ventricular cardiomyocyte like phenotype. Within 7 days, the hiPSC‐CMs on aligned scaffolds and TCPS beat synchronously and had similar conductive velocities. These preliminary results show that aligned D‐PHI elastomeric scaffolds allow hiPSC‐CMs to demonstrate important cardiomyocytes characteristics, critical to enabling their future potential use for cardiac tissue regeneration.