bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lieux de culte et espace urbain
Authors: Bertrand Audrey , Estienne Sylvia 
Published: July 2022

Cette contribution examine les apports de la documentation archéologique et épigraphique des lieux de culte de la Rome antique dans les dernières décennies au prisme du concept de « paysage religieux ». Cette approche met en lumière notamment les phénomènes de voisinage, de cohabitation et d’attractivité qui caractérisent les lieux de culte au sein de l’espace vécu, à l’échelle du quartier et de la ville. L’attention accrue à l’agency rituelle, en particulier lors des processions, invite à une relecture des espaces urbains à travers un réseau symbolique et en révèle les dynamiques. Les découvertes récentes comme le bois sacré d’Anna Perenna s’inscrivent dans des perspectives récemment renouvelées, comme celle des rapports entre pratiques magiques et pratiques cultuelles ou du rôle des sanctuaires dits extra-urbains. Étudier la topographie religieuse de Rome ouvre ainsi à de nouveaux questionnements sur les interactions entre lieux de culte et espace urbain et à l’écriture d’une histoire globale de l’Vrbs.
Gut Microbiota-Derived Unconventional T Cell Ligands: Contribution to Host Immune Modulation
Authors: Oh Sungwhan F , Jung Da-Jung , Choi Eungyo 
Published: July 2022

Abstract
Besides the prototypic innate and adaptive pathways, immune responses by innate-like lymphocytes have gained significant attention due to their unique roles. Among innate-like lymphocytes, unconventional T cells such as NKT cells and mucosal-associated invariant T (MAIT) cells recognize small nonpeptide molecules of specific chemical classes. Endogenous or microbial ligands are loaded to MHC class I–like molecule CD1d or MR1, and inducing immediate effector T cell and ligand structure is one of the key determinants of NKT/MAIT cell functions. Unconventional T cells are in close, constant contact with symbiotic microbes at the mucosal layer, and CD1d/MR1 can accommodate diverse metabolites produced by gut microbiota. There is a strong interest to identify novel immunoactive molecules of endobiotic (symbiont-produced) origin as new NKT/MAIT cell ligands, as well as new cognate Ags for previously uncharacterized unconventional T cell subsets. Further studies will open an possibility to explore basic biology as well as therapeutic potential.
Traditional Chinese Medicine Pattern Classification and Herbal Medicine for COVID-19
Authors: Gao Zhen , Liu Ying-Ying , Chen Ye-Meng , Dong Jing-Cheng 
Published: July 2022

Background:
Traditional Chinese medicine (TCM) plays a crucial role in the prevention and control of coronavirus disease 2019 (COVID-19).

Objective:
The study aimed to reveal the distribution characteristics of COVID-19 TCM syndrome types and syndrome elements and the law of TCM treatment and medication.

Methods:
The TCM diagnosis and treatment protocol for COVID-19 and clinical research data were obtained through network retrieval, and Revman 5.3 and SPSS 23.0 were employed to analyze the composition of TCM syndromes and the situation of TCMs in meta and frequency.

Results:
The top three TCM syndromes of COVID-19 included damp-heat accumulation in the lung pattern, damp abundance due to spleen deficiency, and epidemic toxin invading the lung pattern, while the syndrome elements were dampness, heat, and toxin. Gypsum fibrosum, Pogostemonis herba, and Armeniacae semen were identified as the commonly used drugs. Different syndrome elements were identified at lung disease location: Forsythiae fructus, Glycyrrhizae radix, and Armeniacae semen can be used for “wind;” Glycyrrhizae radix, Armeniacae semen, and Scutellariae radix can be used for “Heat;” Armeniacae semen, Sheng Gypsum fibrosum, and Ephedrae herba can be used for “Toxin;” Ephedrae herba, Armeniacae semen, and Atractylodis rhizome can be used for “Damp;” Magnoliae officinalis Cortex, Ephedrae herba, and Zingiberis Rhizoma recens can be used for “cold;” and Armeniacae semen, Gypsum fibrosum, Ephedrae herba, and Lepidii/Descurainiae semen can be used for “epidemic.”

Conclusion:
The establishment of a treatment scheme based on the classification of disease syndrome elements should be considered for sudden infectious diseases, such as COVID-19. Pogostemonis herba, Armeniacae semen, Gypsum fibrosum, and Glycyrrhizae radix should be considered as effective drugs from TCM for the treatment of COVID-19.
Sexual Dysfunction in Women with Type 2 Diabetes Mellitus
Authors: Gupta Manisha , Shukla Rishi , Verma Shivendra , Kalhan Atul 
Published: July 2022

Introduction:
There is a dearth of studies evaluating sexual dysfunction in women with Type 2 Diabetes Mellitus (T2DM), despite anecdotal evidence suggesting an association between glycemic control and female sexual health.

Materials and Methods:
An observational cross-sectional study was carried out in 100 women with T2DM under follow-up at a regional diabetes center. Validated questionnaires, Female Sexual Function Index (FSFI), and Female Sexual Distress Scale (FSDS) were used to collate the prevalence and severity of female sexual dysfunction (FSD) in the subjects. Anthropometric and metabolic parameters were recorded by clinical examination and blood tests, respectively.

Results:
FSD was reported in 18% (95% CI: 10.5–25.5%) of the women enrolled in the study. The women with FSD were significantly older (50 ± 9.3 years vs. 43.9 ± 8.2 years, P = 0.006). In addition, the mean body mass index (BMI) (31.96 ± 5.5 Kg/m2 vs. 28.98 ± 4.63Kg/m2, P = 0.02) and waist circumference (38.88 ± 6.6 inches vs. 35.54 ± 5.62 inches, P = 0.03) were higher in the women with FSD compared with those without FSD. However, we observed no statistically significant association between FSD and the duration of diabetes, level of glycemic control, and serum testosterone level.

Conclusion:
Advanced age, higher BMI, and central adiposity were related with the development of FSD, whereas the duration of diabetes and level of HbA1c did not increase FSD risk.
Comparing Time to Intensification between insulin Degludec/Insulin Aspart and Insulin Glargine
Authors: Kovil Rajiv 
Published: July 2022

Background and Aims:
The objective of the study was to compare the percent of patients with type 2 diabetes (T2D) requiring dose intensification and the time to dose intensification in patients on insulin degludec/insulin aspart (IDegAsp) versus those on basal insulin.

Materials and Methods:
Data were collected through retrospective chart review of patients with T2D being treated with insulin at a single center in India. The increase from once daily (OD) to twice daily dose or the addition of prandial insulin was considered as dose intensification. Chi-square test was conducted to compare the groups.

Results:
In the IDegAsp group (n = 515), 455 patients continued on the OD dose, and 60 patients (11.6%) were intensified. In the insulin glargine (IGlar) group (n = 173), 143 patients remained on the initial dose and 30 patients (17.34%) were intensified. Fewer patients on IDegAsp required treatment intensification than those on IGlar (P = 0.05). The time to treatment intensification (±standard deviation) was 11.98 ± 7.81 months in the IDegAsp group and 6.71 ± 6.86 months in the IGlar group. The time to treatment intensification was significantly longer in the IDegAsp than in the IGlar group (P = 0.0023).

Conclusions:
The study shows that significantly fewer patients on IDegAsp required dose intensification than those on IGlar. Additionally, the time to dose intensification was significantly delayed in patients on IDegAsp as compared to IGlar. However, HbA1c reduction with IGlar (nonintensified) was significant only at 6 months and failed to reach significance at 12 months, thereby pointing toward an early need for treatment intensification.
Pattern of Presentation in a Community Outpatient Wound Clinic
Authors: Iyun Ayodele Olukayode , Iyun Omobolaji Ibukun 
Published: July 2022

Introduction:
The management of patients with cutaneous wounds entails both inpatient and outpatient care. There is scarcity of dedicated community wound clinics in Nigeria to guarantee appropriate management of especially difficult-to-heal wounds on outpatient basis. The aim of the study was to describe the pattern of presentation of patients with wounds at a community outpatient wound clinic (COWC).

Materials and Methods:
Consecutive patients with wounds who presented to a COWC in the city of Ibadan from October 2015 to December 2021 were included. Descriptive analysis was done using IBM® SPSS® Statistics 21.

Results:
Two hundred and forty-four patients with wounds presented at the wound clinic. There was a slight female preponderance of 52%. Almost one-tenth of the patients were 80 years old and above. Post-traumatic wounds were the commonest type of wounds accounting for 15.3% of the patients seen. This was followed by diabetic wounds (14.9%) and haemoglobinopathic (sickle cell) wounds (13.2%). In patients with leg wounds who presented during the period, diabetic wounds (24.4%) was the commonest aetiology, haemoglobinopathic leg wounds accounted for 23% of patients, and post-traumatic leg wounds were seen in 20% of the patients.

Conclusion:
COWC is an option to managing complex wounds from various aetiology. Best practices in wound care will result in more favourable outcome in difficult-to- heal wounds and early referrals from wound clinics for limb salvaging procedures are additional benefits.
Glycerolised Skin Allografts for Extensive Burns in Low- and Middle-income Countries
Authors: Iyun Ayodele Olukayode , Ademola Samuel Adesina , Olawoye Olayinka A. , Michael Afieharo I. , Aderibigbe Rotimi Opeyemi , Iyun Omobolaji Ibukun , Oluwatosin Odunayo M. 
Published: July 2022

Introduction:
There has been a significant improvement in the outcome of treatment of large surface area burns in developed countries. A major contributory factor is an early excision and skin grafting of burn wounds. The initial coverage of large surface area deep burn wounds requires the use of temporary skin substitutes such as allografts due to limited skin autografts. Cadaveric skin allografts are the commonest source of skin allografts in use; however, there may be religious, cultural, cost, or other factors mitigating its availability and routine use in low- and middle-income countries (LMICs). Human skin allografts may be used fresh or stored in tissue banks to ensure its ready availability. The purpose of this review is to promote glycerolised skin allografts as a means of skin preservation in low-resource countries above other modalities cryopreservation due to its cost advantages and relative ease of operation.

Materials and Methods:
A literature search for articles related to human skin allograft use in burn care, skin banks, and glycerolised skin allografts in LMICs was done using PubMed, EMBASE, and Web of Science databases. The key words used were ‘allograft’ and ‘burn’ with a filter in the search for human studies. The relevant references in the articles obtained were also searched for and included in the review

Results:
Sixty-three journal articles were reviewed for contents in line with the objectives of this study.

Conclusion:
Glycerolised skin graft is a viable option for coverage of extensive burns in LMICs.
Correlation between presence of Lumbar Instability, Physical function and Balance in subjects with knee osteoarthritis
Authors: Bhatt Urmi , Shukla Yagna 
Published: July 2022

BACKGROUND AND OBJECTIVES:
Osteoarthritis (OA) of the knee is one of the most common musculoskeletal disorders that increase the global health burden. Various research aimed to improve pain and physical functions in individuals with OA knee have been conducted. However, there is a dearth of research evaluating coexisting lumbar instability and its impact on physical function limitation and risk of fall in individuals with knee OA, while there is a pool of research on kinetic chain evaluation including lumbar spine for the athletic population for injury prevention.

METHODOLOGY:
Twenty-two individuals with OA knee, aged 50–65 years (male or female) willing to participate in the study were included in the study. Demographic details including age, body mass index (BMI), and duration of knee pain were recorded. All the individuals were screened for the presence of lumbar segmental instability (using passive lumbar extension test), balance (using Dynamic Gait Index), and physical function using mWOMAC.

RESULTS:
Data were analyzed using SPSS. There were significantly greater (P < 0.05) deficits in balance and function of individuals with the presence of clinical lumbar segmental instability. In addition, BMI and duration of knee pain also correlated positively with balance and function deficits in all individuals.

CONCLUSION:
The presence of lumbar segmental instability in individuals with OA knee puts them at greater risk of falls due to altered balance and limits functional ability as well.
Comparison of effectiveness of electrical stimulation, myofascial release, and conventional physiotherapy over acupuncture points (GB21, SI14) on upper trapezius in female basketball players
Authors: Jha Sanjiv , Bajpai Sanket , Mishra Ruchi , Brahm Vaishali , Bhargava Ananya 
Published: July 2022

AIM:
The aim of the study is to compare the effectiveness of electrical stimulation, myofascial release (MFR), and conventional physiotherapy over acupuncture points (GB21, SI14) on the upper trapezius in female basketball players.

METHODOLOGY:
The study included 30 patients with unilateral myofascial trigger points (MTrPs) present on acupuncture points GB2l (midway between shoulder and vertebral column) and SI14 (3 cm lateral to lower border of spinous process of first thoracic vertebra) on the upper trapezius, between the age group of 18 and 30 years. The patients were allotted alternatively to Group A, Group B, and Group C, respectively. Preparticipation evaluation was done. Group A received electrical stimulation with exercise, Group B received MFR with exercise, and Group C received cold pack with exercise. Posttreatment evaluation is conducted on the 7th day of treatment.

RESULTS:
The results showed that Group B has significant decrease in pain and increase in lateral bending of the cervical spine to the opposite side at posttest values as compared to Group A and Group C.

CONCLUSION:
All three groups have got beneficial effects in reducing pain intensity and increasing lateral bending of the cervical spine to the opposite side. Group B shows more significant effect in decrease in pain and increase in lateral bending of the cervical spine to the opposite side in female basketball players with MTrP over acupoints GB21, SI14 on the upper trapezius.
Wheelchair Axle Position Effect on the Propulsion Performance of Persons With C7 Tetraplegia: A Repeated-Measures Study
Authors: Freixes Orestes , Fernández Sergio Anibal , Passuni Diego Alejandro , Gatti Marcelo Andrés , Buffetti Eliana , Rivas Maria Elisa , Olmos Lisandro Emilio , Crespo Marcos José 
Published: July 2022

Objectives
To assess the changes in speed, stroke frequency, acceleration, and shoulder range of motion (ROM) associated with different wheelchair axle positions in people with chronic C7 tetraplegia.

Methods
This repeated-measures study was conducted at the Chronic Spinal Cord Injury Unit, FLENI Escobar, Argentina. The speed, stroke frequency, acceleration, and shoulder ROM during wheelchair propulsion were measured in nine participants with C7 spinal cord injury (SCI) in four different axle positions (forward and up, forward and down, backward and down, backward and up). Two strokes performed at maximum speed were analyzed on a smooth level vinyl floor in a motion analysis laboratory. Data were analyzed for significant statistical differences using the Friedman test and the Wilcoxon signed rank test.

Results
Our study showed significant differences in the speed with axle position 1 (1.57 m/s) versus 2 (1.55 m/s) and position 2 (1.55 m/s) versus 4 (1.52 m/s). The shoulder ROM showed a significant difference in the sagittal plane in position 2 (59.34 degrees) versus 3 (61.64 degrees), whereas the stroke frequency and the acceleration parameters showed no statistically significant differences with the different rear axle positions.

Conclusions
Our study showed that modifying the rear axle position can improve the propulsion speed and produce changes in the shoulder ROM in the wheelchair propulsion of individuals with C7 SCI.
Seguridad y calidad oncológica de la cirugía por cáncer colorrectal en un centro docente universitario
Authors: Liz Alejandra , Castro Alvaro , Soumastre Alejandro , Lavega Álvaro , Fagúndez Natalia , Viola Malet Marcelo 
Published: July 2022

Introducción: Es fundamental que cada equipo quirúrgico audite la calidad de sus cirugías, mas en un centro docente, el cual debe garantizar el correcto aprendizaje de la cirugía oncológica.
Objetivo: evaluar la calidad de la cirugía oncológica por cáncer colorrectal en un centro universitario.
Material y métodos: estudio retrospectivo sobre una base de datos prospectiva de pacientes operados por cáncer colorrectal en el hospital Pasteur, entre 2017-2021. Se analizó la seguridad de la cirugía, la calidad oncológica de la resección y el nivel formativo del cirujano principal.
Resultados: de los 89 pacientes, no hubo diferencias de género. La mediana de edad fue 69 años. Predominaron los pT3 (50%) y pT4 (36,5%), pN0 (60%) y pN1 (29%). Los procedimientos mas realizados fueron la colectomía derecha (43%) y la resección anterior de recto (40%). El 69% fueron laparoscópicos, con una conversión del 5%. La dehiscencia anastomótica fue 9,8%, mas frecuente en las anastomosis ileotransverso (13%) y las manuales (16%). Hubo 10% de complicaciones quirúrgicas moderadas-severas (grados 3 y 4 de Clavien-Dindo). La tasa de reintervención fue 11% y la mortalidad 2%. La mediana de internación fue 7 días. El número de ganglios resecados tuvo una mediana de 16. No hubo compromiso del margen distal y el circunferencial estuvo libre en 85%. La fascia rectal fue completa/casi completa en 93%. Casi 70% de las cirugías fue realizada por cirujanos jóvenes.
Conclusión: en nuestro centro, la cirugía por cáncer colorrectal cumple con estándares internacionales de seguridad y calidad oncológica. La mayoría de los procedimientos fueron realizados por los jóvenes, en forma tutorizada.
ИСКУССТВЕННЫЙ ИНТЕЛЛЕКТ И АВТОМАТИЗАЦИЯ В НАВИГАЦИИ И
СУДОХОДСТВЕ. СНИЖЕНИЕ ВЛИЯНИЯ ЧЕЛОВЕЧЕСКОГО ФАКТОРА
Authors: Гладкова А.М. , Марушевский М.В. , Фаустова О.Г. 
Published: July 2022

Человеческий фактор часто является причиной катастроф и происшествий во всём
мире, и ученые уже всерьез задумываются о замене человека в скором будущем во многих
профессиональных сферах. Искусственный интеллект уже давно используется во всех
сферах человеческой жизни, и судоходство не является исключением. Эксплуатация систем в
помощи принятия решений с глубоким машинным обучением не ограничивается только
помощью в построении маршрута, но также распространяется на снижение рисков и
предотвращения столкновений в море. Базой для машинного обучения являются конвенции –
унифицированные правила, регулирующие определенные сферы судовой навигации. Однако
любая модернизация связана с определенными рисками. Данная статья ориентирована на
оценку не только подобных рисков, но и перспектив автоматизации судоходства в целом.
Why attacks on Doctors are Increasing?
Authors: Kadu Dr. Sandeep 
Published: July 2022

Every day we watch or read news about patient’s or their relative’s conflicts with doctor. Hence question arises Why in recent years such incidences are increasing? I think as medical practioner we have to introspect on this issue.
As per my opinion and experience patient as well as doctors both are equally responsible for such conflicts. As we all know truth is always bitter and, in this article, I would like to point out some sensitive areas of medical practice, there can be irreconcilable difference over this discussion.
Assessment of Cardiopulmonary Resuscitation Knowledge and Attitude Amongst Interns and Junior Residents of Tertiary Care Centre
Authors: Kshirsagar Ms. Trisha , Kshirsagar Dr. Roop , Kadu Dr. Sandeep 
Published: July 2022

Introduction: Cardiopulmonary resuscitation (CPR) is a life saving procedure and adequate knowledge and skills related to CPR are essential for all medical students. This study was undertaken to compare knowledge and practice related to updated CPR guidelines by American Heart Association (AHA) 2020 between junior residents and interns. Methods: This is a questionnaire-based study prepared on Google form consisting of 22 questions on CPR. The participants were all from DVVPF’s medical college and hospital, Ahmednagar and all those who were willing to participate were included. They were advised to read carefully and allowed to tick one best response among the options. Results: Total of 124 participants included 41 junior residents and 83 interns. An average overall correct response from both the group was 14.48 (65.81 %). Interns score was average of 13.024 (59.20 %) and so had lower correct response than junior residents, who had average score of 18.39 (83.59%). But there was a considerable difference in pattern of correct response between both the groups. Among theory knowledge-based questions (Part 1), junior residents had an average of 8.707 correct answers out of 11 (79.15%) which is more correct answers than interns who have average 5.90 correct (53.63%). Similarly, in terms of practical knowledge, junior residents had an average score 9.682 out of 11 (88.026%) compared to interns who had an average of 6.518 out of 11 (59.27%). Conclusion: The study showed poor knowledge about CPR among the interns. More practical based teaching should be employed in MBBS curriculum. Periodical reinforcement and refresher courses should be part of curriculum.