bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thrombectomy aspiration post-market study in acute stroke with the Q aspiration catheter: the TAPAS study
Authors: Espinosa de Rueda Mariano , Ballenilla Marco Federico , Garmendia Lopetegui Eñaut , Pumar Jose M , Zamarro Joaquin , García-Villalba Blanca , Díaz-Pérez Jose , Mosqueira Antonio , Lüttich Alex , Larrea Jose-Angel , Parrilla Guillermo 
Published: May 2022

BackgroundThe Q Aspiration Catheter (MIVI Neuro) has demonstrated greater aspiration flow rates and ingestion forces compared with conventional catheters in vitro. The safety and performance of the Q Catheter was assessed using a direct aspiration first pass technique in patients with acute ischemic stroke at four neurointerventional centers in Spain.MethodsWe included adult patients who underwent mechanical thrombectomy between March 2019 and March 2020 using the Q Catheter as first-line therapy. Performance endpoints included final successful revascularization of the target vessel (defined as modified thrombolysis in cerebral infarction (mTICI) grade 2B/3), first pass revascularization, and overall Q Catheter revascularization. Safety endpoints were symptomatic intracranial hemorrhage (sICH), embolization to new territory (ENT), and procedural complications. Modified Rankin Scale (mRS) score and all-cause mortality were also assessed.ResultsForty-five subjects were enrolled. The Q Catheter successfully navigated to the lesion in 95.5% (43/45) of patients. Final successful mTICI 2B/3 revascularization was achieved in 93.3% (42/45), first pass mTICI 2B/3 revascularization with the Q Catheter was 55.3% (21/38), and overall with Q Catheter mTICI 2B/3 revascularization was 65.8% (25/38). Favorable clinical outcome of mRS 0–2 was achieved in 55.6% (25/45). There were no cases of ENT. sICH and mortality rates were 2.2% (1/45) and 13.3% (6/45), respectively.ConclusionIn this multicenter, observational study, the Q Aspiration Catheter used as first-line therapy demonstrated a good and safe profile in terms of navigation, revascularization, and safety in patients with acute ischemic stroke.
Kolkata-Coventry comparative registry study of acute heart failure: an insight into the impact of public, private and universal health systems on patient outcomes in low–middle income cities (KOLCOV HF Study)
Authors: Banerjee Suvro , Halder Swapan Kumar , Kimani Peter , Tran Patrick , Ali Danish , Roelas Marina , Weight Nicholas , Dungarwalla Moez , Banerjee Prithwish 
Published: May 2022

IntroductionSurvival gaps in acute heart failure (AHF) continue to expand globally. Multinational heart failure (HF) registries have highlighted variations between countries. Whether discrepancies in HF practice and outcomes occur across different health systems (ie, private, public or universal healthcare) within a city or between countries remain unclear. Insight into organisational care is also scarce. With increasing public scrutiny of health inequalities, a study to address these limitations is timely.MethodKOLCOV-HF study prospectively compared patients with AHF in public (Nil Ratan Sircar Hospital (NRS)) versus private (Apollo Gleneagles Hospital (AGH)) hospitals of Kolkata, India, and one with universal health coverage in a socioeconomically comparable city of Coventry, England (University Hospitals Coventry & Warwickshire (UHCW)). Data variables were adapted from UK’s National HF Audit programme, collected over 24 months. Predictors of in-hospital mortality and length of hospitalisation were assessed for each centre.ResultsAmong 1652 patients, in-hospital mortality was highest in government-funded NRS (11.9%) while 3 miles north, AGH had significantly lower mortality (7.5%, p=0.034), similar to UHCW (8%). This could be attributed to distinct HF phenotypes and differences in clinical and organisational care. As expected, low blood pressure was associated with a significantly greater risk of death in patients served by public hospitals UHCW and NRS.ConclusionMarked differences in HF characteristics, management and outcomes exist intra-regionally, and between low–middle versus high-income countries across private, public and universal healthcare systems. Physicians and policymakers should take caution when applying country-level data locally when developing strategies to address local evidence-practice gaps in HF.
Effects of soil texture and moisture on the host searching abilities of Steinernema siamkayai against Bactrocera latifrons
Authors: Ta-oun Puping , Ehlers Ralf-Udo , Nimkingrat Prakaijan 
Published: May 2022

Summary
Soil texture and moisture have significant effects on the infectivity and persistence of entomopathogenic nematodes (EPN). Both EPN and chili fruit flies (Bactrocera latifrons) spend most of their lifetime in soil, therefore making it possible to consider the successful use of EPN against chili fruit flies. This study aimed to investigate the effects of soil texture and moisture contents on chili fruit fly pupation and adult emergence, and on the infectivity of the EPN, Steinernema siamkayai, against this pest. The results revealed that the highest percentage of pupation occurred at a depth of 2 cm in all soil types. At a depth of 5 cm in the sandy clay loam only, no pupation of B. latifrons was observed. The adult emergence ranged from 51.9 to 82.5%, with significant differences between soil types. The horizontal movement of S. siamkayai showed that the concentration of EPN at a rate of 20 000 dauer juveniles pupa−1 yielded maximum pupae mortality (77.5-91.3%) in all soil types containing 15% moisture. In the vertical displacement test, S. siamkayai was capable of killing pupae up to a distance of 15 cm in all soil types. These results confirmed the potential of S. siamkayai to be used within pest control programmes of various soil textures, as long as the soil moisture contents allow its dispersal and host infection.
Lost and Gone: A Representational Study of Bronze Ornaments in the Ancient Dian Kingdom, China
Authors: Wu Liancai , Zhu Peng , Tian Yu , Lin Haitao 
Published: May 2022

Abstract
Amidst its diverse prehistoric civilizations, the Shizhaishan culture has provided evidence concerning the lives the ancient Dian people more than 2,000 years ago with its vivid and figurative excavated artifacts exhibiting exquisite craftsmanship and varied forms. One of the artifacts unearthed from Tomb M6, the “Golden Seal of the King of Dian,” matches exactly with descriptions in the Historical Records, serving as the only domestic case in which the “the dual evidence method” of historical research has been applied. Bronze ornaments embodying the sophistication of Bronze Age civilization in the Dian Kingdom have been excavated from this and subsequent large tombs, the cultural interaction between Dian and the Bronze Age plaques of the Scythians on the Eurasian steppe and the North System implies exchange between different prehistoric civilizations an issue that is still source of current academic debate. This paper provides an iconographic study of the Dian Kingdom bronze ornaments through the study of decorative motifs, inlaid materials, and the casting and gilding techniques. In this respect, we explore social production in the Dian Kingdom and contact between the civilizations of the East and the West across the “golden latitude” and connected by the “Southern Silk Road.” Our paper concludes that Bronze Ornaments are the concrete embodiment of the Ancient Chinese South-west highland and Western civilization in terms of the integration in the integration Dian culture. Therefore, this subject of is great value in terms of our understanding of both regional prehistory and cultural development.
Governing Migration and Asylum Amid Covid-19 and Legal Precarity in Turkey
Authors: Ozkul Derya 
Published: May 2022

Abstract
Legal status and associated rights to access state services become even more important at times of crises like the Covid-19 pandemic. By reviewing legal amendments, central government and municipalities’ policies and policymakers’ statements, this article examines the example of Turkey, which is home to around 4 million undocumented migrants, asylum seekers and refugees. The Turkish state-provided Covid-19 treatment in the ‘emergency’ scope of healthcare for all residents irrespective of their legal status. However, structural problems left undocumented migrants and refugees faced with three significant obstacles. These obstacles were the requirement to test positive for Covid-19; the requirement to access primary healthcare to be referred to hospitals and to reside in the city of registration to access that primary healthcare; and the fear of losing employment, being evicted from housing or being deported by the authorities. Additionally, growing political uncertainty and a deteriorating economic situation have contributed to growing anti-migrant movements in the country. Not only have undocumented migrants and refugees had limited access to public health provisions, but they were also at greater risk of being considered to be a threat to public health and public security. The article concludes by showing that legal precarity brings even more vulnerability at times of crisis and by suggesting future areas of research.
Investigating the Crossmodal Influence of Odour on the Visual Perception of Facial Attractiveness and Age
Authors: Chen Yi-Chuan , Spence Charles 
Published: May 2022

Abstract
We report two experiments designed to investigate whether the presentation of a range of pleasant fragrances, containing both floral and fruity notes, would modulate people’s judgements of the facial attractiveness (Experiment 1) and age (Experiment 2) of a selection of typical female faces varying in age in the range 20–69 years. In Experiment 1, male participants rated the female faces as less attractive when presented with an unpleasant fragrance compared to clean air. The rated attractiveness of the female faces was lower when the participants rated the unpleasant odour as having a lower attractiveness and pleasantness, and a higher intensity. In Experiment 2, both male and female participants rated the age of female faces while presented with one of four pleasant fragrances or clean air as a control. Only the female participants demonstrated a crossmodal effect, with the pleasant fragrances inducing an older rating for female faces in the 40–49-years-old age range, whereas a younger rating was documented for female faces in the 60–69-years-old age range. Taken together, these results are consistent with the view that while the valence of fragrance (pleasant versus unpleasant) exerts a robust crossmodal influence over judgements of facial attractiveness, the effects of pleasant fragrance on judgements of a person’s age appear to be less reliable. One possible explanation for the differing effect of scent in the two cases relates to the fact that attractiveness judgements are more subjective, hedonic, and/or intuitive than age ratings which are more objective, cognitive-mediated, and/or analytic in nature.
The Suitability and Characteristics Analysis of Key Science Inquiry Activities in the 2015 National Science Curriculum in Korea
Authors: Son Mi Hyun , Lim Wanchul , Son Jeongwoo , Jeong Dae Hong 
Published: May 2022

Abstract
The suitability and characteristics of middle school inquiry activities in the 2015 National Curriculum of Science in Korea were studied from the perspective of eight science teachers with rich experience in teaching science inquiry activities. In-depth interviews revealed problems teachers experienced while conducting inquiry classes. Problems were classified into five categories: inquiry level, method, tool, inquiry result, difficulty in guidance, and safety. Based on this analysis, strategies for an inquiry improvement plan are suggested, including that quantitative inquiry requiring numerical interpretation of data obtained from the process of inquiry should be emphasized. Concrete guidance of inquiries should be provided for non-major science teachers to help them instruct inquiries more easily. Institutional improvement is needed to develop curriculum activities and the improvement of science lab and classroom environments are necessary for conducting inquiry activities utilizing technology. The results of this study can contribute to the development of science inquiry activity programs.
The Definition and Mechanisms of Condensation (Takṯīf) in Modern Arabic Poetry. Muqāṭaʿa by Ḫalīl Muṭrān and Raʾs by Sinān Anṭūn as Examples
Authors: Sliman-Baraky Rawand 
Published: May 2022

Abstract
This article examines the term “condensation” (takṯīf) and its presence in Arabic poetry. It explains the meaning and importance of the term as well as its relation to the specific meanings poets seek to convey in the text. The study then searches for the mechanisms that create textual condensation, whose ratio is determined by condensation’s very presence in any given text. As a result of this study, this article will determine the factors that strengthen or weaken textual condensation in Arabic poetry.
To clarify how the mechanisms of condensation are employed in poems and how these mechanisms contribute to the meaning that we draw as readers of particular poems, we will apply our theoretical knowledge to two poems from two different periods. To obviate the effect of text length on condensation, we have chosen poems which contain a similar number of words: Muqāṭaʿa by Ḫalīl Muṭrān (1872–1949) and Raʾs by Sinān Anṭūn (born 1967). Our analysis will then determine which poem is more condensed and the reasons behind that condensation.
Do national policies for complaint handling in English hospitals support quality improvement? Lessons from a case study
Authors: van Dael J , Reader TW , Gillespie AT , Freise L , Darzi A , Mayer EK 
Published: May 2022

Objectives A range of public inquiries in the English National Health Service have indicated repeating failings in complaint handling, and patients are often left dissatisfied. The complex, bureaucratic nature of complaints systems is often cited as an obstacle to meaningful investigation and learning, but a detailed examination of how such bureaucratic rules, regulations, and infrastructure shape complaint handling, and where change is most needed, remains relatively unexplored. We sought to examine how national policies structure local practices of complaint handling, how they are understood by those responsible for enacting them, and if there are any discrepancies between policies-as-intended and their reality in local practice. Design Case study involving staff interviews and documentary analysis. Setting A large acute and multi-site NHS Trust in England. Participants Clinical, managerial, complaints, and patient advocacy staff involved in complaint handling at the participating NHS Trust ( n=20). Main outcome measures Not applicable. Results Findings illustrate four areas of practice where national policies and regulations can have adverse consequences within local practices, and partly function to undermine an improvement-focused approach to complaints. These include muddled routes for raising formal complaints, investigative procedures structured to scrutinize the ‘validity’ of complaints, futile data collection systems, and adverse incentives and workarounds resulting from bureaucratic performance targets. Conclusion This study demonstrates how national policies and regulations for complaint handling can impede, rather than promote, quality improvement in local settings. Accordingly, we propose a number of necessary reforms, including patient involvement in complaints investigations, the establishment of independent investigation bodies, and more meaningful data analysis strategies to uncover and address systemic causes behind recurring complaints.
Unusual Neurological Manifestation of Langerhans Cell Histiocytosis in an Adult
Authors: Achour Imen , Kharrat Ines , Hbaieb Youssef , Ben Ayed Mariam , Mnejja Malek , Hammami Bouthaina , Souissi Basma , Charfeddine Ilhem 
Published: May 2022

Langerhans Cell Histiocytosis is a rare disorder characterized by an abnormal proliferation of Langerhans cells in one or multiple organs. It rarely presents with a central vestibular involvement. We report a case of a multisystem Langerhans Cell Histiocytosis with mucosal, hepatic, and neurological involvement, presenting with dizziness and balance disorders. A 39-year-old woman with a histopathologically confirmed mucosal palatal Langerhans Cell Histiocytosis presented with a history of dizziness for a year. Vestibular examination revealed a saccadic eyes pursuit, an up beating spontaneous nystagmus, a bilateral gaze nystagmus and a prolonged positional nystagmus, in the supine roll test. Pure tone audiometry showed a slight left sensorineural hearing loss at the 8000 Hz frequency. Computed tomography (CT) scan showed a bilateral maxillary sinus fullness and a peripheral osteosclerosis of the surrounding bony walls. Hepatic magnetic resonance imaging (MRI) showed a typical hepatic involvement with a hepatomegaly with countless cysts. Temporal bone CT scan and MRI were normal. Cerebral MRI showed an hyperintense nodular signal at T2 FLAIR weighted images lateral to the right pons, at the level of the left middle cerebellar peduncle and at the left mesencephalon. Balance disorders can rarely present a sign of a degenerative neurological cerebellar involvement. Such a rare manifestation can present in different neurological disorders such as Langerhans’ cell Histiocytosis.
Factors associated with failure of high-flow nasal cannula oxygen therapy in patients with severe COVID-19: a retrospective case series
Authors: Ma Xiao-Huan , An Meng-Meng , Yin Fang , Zhang Jie , Peng Meng-Yun , Guan Hong , Gong Ping 
Published: May 2022

Objective To identify factors associated with high-flow nasal cannula (HFNC) therapy failure in patients with severe COVID-19. Methods We retrospectively examined clinical and laboratory data upon admission, treatments, and outcomes of patients with severe COVID-19. Sequential Organ Failure Assessment (SOFA) scores were also calculated. Results Of 54 patients with severe COVID-19, HFNC therapy was successful in 28 (51.9%) and unsuccessful in 26 (48.1%). HFNC therapy failure was more common in patients aged ≥60 years and in men. Compared with patients with successful HFNC therapy, patients with HFNC therapy failure had higher percentages of fatigue, anorexia, and cardiovascular disease; a longer time from symptom onset to diagnosis; higher SOFA scores; a higher body temperature, respiratory rate, and heart rate; more complications, including acute respiratory distress syndrome, septic shock, myocardial damage, and acute kidney injury; a higher C-reactive protein concentration, neutrophil count, and prothrombin time; and a lower arterial partial pressure of oxygen/fraction of inspired oxygen (PaO2/FiO2). However, male sex, a low PaO2/FiO2, and a high SOFA score were the only independent factors significantly associated with HFNC therapy failure. Conclusions Male sex, a low PaO2/FiO2, and a high SOFA score were independently associated with HFNC therapy failure in patients with severe COVID-19.
Human Factors and Ergonomics Considerations for Aging-in-Place Part 2: The Intersection of Environment and Technology
Authors: Owens Otis L. , Beer Jenay M. 
Published: May 2022

This article is part 2 of a two-part series focused on aging-in-place. Aging-in-place is a term that has been increasingly used over the past 40 years to describe the process of remaining in one’s home. In attempt to advance the discussion on the future of aging-in-place, this feature series provides an overview of the grand challenges to aging-in-place with an emphasis on human factors and ergonomics considerations. Part 2 will discuss a variety of ways to conceptualize “place” and describe the need for integrated technology within the home and beyond.
Baricitinib is Effective in Treating Progressing Vitiligo in vivo and in vitro
Authors: Dong Jie , Huang Xuan , Ma Li-Ping , Qi Fei , Wang Si-Nian , Zhang Zi-Qin , Wei Shi-Nan , Gao Ling , Liu Fang 
Published: May 2022

Objective To evaluate the clinical efficacy and safety of baricitinib, a Janus kinase (JAK) inhibitor, in treating patient with progressing vitiligo, and to further explore the regulation of baricitinib on melanocytes (MCs) in vitro. Methods Four patients with progressing vitiligo were treated with oral baricitinib for a total of 12 weeks. MCs were cultured in vitro and irradiated by high-dose ultraviolet B (UVB, 150mJ/cm2) to make an MC damaged model (MC-Ds). Baricitinib was added at a final concentration of 25 μM. Dopamine staining and NaOH method were used to measure the tyrosinase activity and melanin level, respectively, real-time quantitative polymerase chain reaction (RT-qPCR) was used to measure the mRNA levels of tyrosinase (TYR), tyrosinase-related protein-1 (TRP-1). Results Significant re-pigmentation was observed in the week 12 without obvious side effects. Depigmentation occurred in 2 patients at the 3-month follow-up. Laboratory research found that higher doses of UVB irradiation (150mJ/cm2) could decrease melanin content of MCs, baricitinib (25 μM) could significantly promote tyrosinase activity, melanin content, and TYR, TRP-1 gene expression of MC-Ds. Conclusion Our preliminary study showed that baricitinib was effective and safe in treating progressing vitiligo. Baricitinib could promote tyrosinase activity, melanin content and TYR, TRP1 gene expression of MC-Ds in vitro.
The Effects of Tai Chi and Baduanjin Activities on Physical Interventions With Substance Use Disorders: A Systematic Review and Meta-analysis
Authors: Tang Zhiming , Zhu Zhicheng , Zhang Xia , He Ying 
Published: May 2022

Objective: To evaluate the effect of Tai Chi (TC) and Baduanjin (Bdj) activities on the physical intervention of compulsory segregation drug addicts through a meta-analysis system. Methods: Six commonly used databases were searched by computer to collect publicly available studies on the physical interventions of TC and Bdj activities for drug addicts from the time of database construction to May 2021. Two researchers independently screened the literature according to the inclusion and exclusion criteria, jointly extracted the data, and evaluated the quality of the literature, and conducted Meta-analysis using RevMan 5.4 software. Results: A total of 16 randomized controlled trials (RCTs) from 15 publications were included. Meta-analysis indicate that compared with the control group, TC and Bdj had significant effects on blood pressure, lung capacity, heart rate, closed-eye single-leg stand, and seated forward bending in drug addicts, as evidenced by: systolic pressure MD=−4.66, 95%CI = [−7.94, −1.39], p = .005; diastolic pressure MD = −3.49, 95%CI=[−5.45, −1.52], p = .0005; spirometry MD = 12.68, 95%CI = [43.83, 197.52], p = .002; heart rate MD = −2.78, 95%CI = [4.76, −.8], p = .006; MD = 1.47, 95%CI = [6.1, 14.84], p < .00,001 for one-leg stand with eyes closed, MD = 3.08, 95%CI = [1.8, 4.36], p < .00,001 for seated forward bend; however, the effect of TC and Bdj on BMI MD = .01, 95%CI = [−.54, .56], p = .97; grip strength MD = .68, 95%CI = [−.99, 2.34], p = .43; body fat percentage MD = .04, 95%CI = [−.59,.67], p = .91 had no effect. Conclusions: Tai Chi and Bdj can improve the cardiovascular system, cardiorespiratory fitness, balance, and body flexibility of drug addicts better than conventional rehabilitation.