bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surgical cytoreduction of deep-seated high-grade glioma through tubular retractor
Authors: Hajtovic Sabastian , Sun James , Multani Jasjit S. , Herrmann Linda L. , Britton Hannah , Gautreaux Jose , Tortolero Lea , Harrison Gillian , Golfinos John G. , Shepherd Timothy M. , Tanweer Omar , Placantonakis Dimitris G. 
Published: November 2022

OBJECTIVE
Maximal safe resection is the goal of surgical treatment for high-grade glioma (HGG). Deep-seated hemispheric gliomas present a surgical challenge due to safety concerns and previously were often considered inoperable. The authors hypothesized that use of tubular retractors would allow resection of deep-seated gliomas with an acceptable safety profile. The purpose of this study was to describe surgical outcomes and survival data after resection of deep-seated HGG with stereotactically placed tubular retractors, as well as to discuss the technical advances that enable such procedures.

METHODS
This is a retrospective review of 20 consecutive patients who underwent 22 resections of deep-seated hemispheric HGG with the Viewsite Brain Access System by a single surgeon. Patient demographics, survival, tumor characteristics, extent of resection (EOR), and neurological outcomes were recorded. Cannulation trajectories and planned resection volumes depended on the relative location of white matter tracts extracted from diffusion tractography. The surgical plans were designed on the Brainlab system and preoperatively visualized on the Surgical Theater virtual reality SNAP platform. Volumetric assessment of EOR was obtained on the Brainlab platform and confirmed by a board-certified neuroradiologist.

RESULTS
Twenty adult patients (18 with IDH–wild-type glioblastomas and 2 with IDH-mutant grade IV astrocytomas) and 22 surgeries were included in the study. The cohort included both newly diagnosed (n = 17; 77%) and recurrent (n = 5; 23%) tumors. Most tumors (64%) abutted the ventricular system. The average preoperative and postoperative tumor volumes measured 33.1 ± 5.3 cm3 and 15.2 ± 5.1 cm3, respectively. The median EOR was 93%. Surgical complications included 2 patients (10%) who developed entrapment of the temporal horn, necessitating placement of a ventriculoperitoneal shunt; 1 patient (5%) who suffered a wound infection and pulmonary embolus; and 1 patient (5%) who developed pneumonia. In 2 cases (9%) patients developed new permanent visual field deficits, and in 5 cases (23%) patients experienced worsening of preoperative deficits. Preoperative neurological or cognitive deficits remained the same in 9 cases (41%) and improved in 7 (32%). The median overall survival was 14.4 months in all patients (n = 20) and in the newly diagnosed IDH–wild-type glioblastoma group (n = 16).

CONCLUSIONS
Deep-seated HGGs, which are surgically challenging and frequently considered inoperable, are amenable to resection through tubular retractors, with an acceptable safety profile. Such cytoreductive surgery may allow these patients to experience an overall survival comparable to those with more superficial tumors.
ПОЛІТИЧНІ АСПЕКТИ БЛАГОДІЙНИХ МАТЧІВ УКРАЇНСЬКИХ ФУТБОЛЬНИХ КЛУБІВ У КРАЇНАХ ЄВРОПИ (У КОНТЕКСТІ РОСІЙСЬКО-УКРАЇНСЬКОЇ ВІЙНИ 2022 Р.
Authors: Кулик Сергій Михайлович 
Published: November 2022

Досліджено суспільно-політичні аспекти благодійних матчів українських футбольних клубів «Динамо» (Київ) та «Шахтар» (Донецьк) у країнах Європи у контексті російсько-української війни 2022 р. Ці матчі мали на меті інформувати міжнародну громадськість про повномасштабне збройне вторгнення Росії в Україну та збір коштів для постраждалих («Динамо»), привернути увагу до великої кількості жертв і постраждалих серед дітей («Шахтар»). Автор стверджує, що благодійне європейське турне українських клубів позитивно вплинуло на імідж фанів і вболівальників клубів, європейського футболу, країн загалом, сприяло покращенню взаєморозуміння між народами. Найбільша кількість «матчів за мир» пройшли у тих країнах, які найбільше допомагають Україні у захисті її територіальної цілісності і самі пережили жахіття війни. Це – Польща, Туреччина і Хорватія. Інші країни також підтвердили свою політичну підтримку України і на «спортивному» фронті. Політичні аспекти товариських матчів українських клубів охопили різні сфери суспільного життя. Серед них: історія (міста держав Європи), інформаційна (боротьба з фейками), політична культура (громадянська позиція відомих осіб, акції і поведінка гравців, глядачів), спортивна (відмова клубів провести матчі), мистецтво (проведення перформансів). Політичні аспекти мали різні вияви: візуальний (оформлення стадіонів, форма футболістів, банери і плакати глядачів), вербальний (скандування і кричалки фанів) і медійний (маніпулювання інформацією).
Методологія статті ґрунтується на логічному, порівняльному, статистичному та когнітивному методах дослідження.
AUTOMATION OF GEODESIC MONITORING HIGH-RISE STRUCTURES
Authors: Medvedskyi Yurii , Annenkov Andriy , Isayev Oleksandr , Demianenko Roman 
Published: November 2022

The article considers the existing methods used in the problem of geodetic monitoring of structures, analyzes the possibilities and gives a preliminary assessment of the accuracy of their use in monitoring high-rise structures. Methods have been identified that allow obtaining measurement results with a high sampling rate and have the potential for automation. Methods have been identified that allow solving the problem of calculating the daily fluctuations of a structure from the effects of solar radiation and wind load separately from the values of heel and draft.
Popular Culture as the Practice of Creating Meanings
Authors: Нurova Inna 
Published: November 2022

The purpose of the article is to conceptualise the phenomenon of modern popular culture as a cultural practice of creating meanings. Methodology. General scientific research methods were applied: analysis and synthesis were used during the review of the main studies of popular culture theorists, by virtue of using systematic method, popular culture was reviewed as a whole, with the coordination of its components, comparative methods was used to collate the features of popular culture with others. The scientific novelty is that the definition of popular culture has been clarified from the perspective of modern Ukrainian cultural studies, considering the meaning-creation processes of its makers. Conclusions. Popular culture is a type of modern culture that recognises the importance of the ordinary, mundane, while everyday life is perceived as an important component of cultural formation. In everyday life, meaning-creation occurs when popular culture makers are not trained specialists, but rather ordinary people, consumers of cultural products, who imbue them with feelings and emotions, give them meaning, based on their own opinions and customs. Such vision allows us to move from a simplified view of the hierarchy of "high" and "low" cultures to a more complex multi-layered picture of the functioning of modern culture.
Key words: popular culture, Cultural Studies, cultural formation, lifeworld, everyday life, cultural practices, sense formation, creation of meanings.
Ergonomic Assessment pada Aktivitas Petani Perkebunan Karet Menggunakan OWAS (Ovako Work Posture Analysis System) (Studi Kasus CV. Eja Nursery, Kalimantan Timur)
Authors: Purnomo Tri Budi , Fathimahhayati Lina Dianati , Pawitra Theresia Amelia , Noviani Jenny 
Published: November 2022

CV. Eja Nursery merupakan salah satu industri pembibitan dan perkebunan karet yang terdapat di Kutai Kartanegara, tepatnya di Jalan Poros Samarinda – Bontang Km 71. Berdasarkan hasil observasi awal didapatkan bahwa terdapat beberapa postur kerja yang tidak ergonomis pada saat petani karet melakukan pekerjaannya yaitu membungkuk pada saat proses penyadapan dan proses pengangkutan getah karet. Postur kerja yang tidak ergonomis ini dapat menyebabkan petani karet mengalami keluhan musculoskeletal disorders (MSDs) yang tinggi. Berdasarkan permasalahan tersebut perlu dilakukan penelitian ergonomic assessment untuk menilai postur kerja pada aktivitas-aktivitas kerja petani karet khususnya di CV Eja Nursery, sehingga nantinya para petani dapat mengetahui tingkat risiko dari postur kerja yang dilakukannya tersebut sehingga dapat diberikan rekomendasi perbaikan sehingga risiko cedera dapat diminimalkan. Metode yang digunakan dalam penelitian ini adalah OWAS. Dari perhitungan menggunakan OWAS dapat disimpulkan bahwa, sebanyak 71% postur kerja berada pada kategori 2 yaitu postur kerja berbahaya bagi sistem muskuloskeletal dan diperlukan perbaikan di masa yang akan datang, 21% postur kerja berada pada kategori 3 yaitu postur kerja berbahaya bagi sistem muskuloskeletal dan diperlukan perbaikan segera mungkin dan 7% postur kerja berada pada kategori 1 yang berarti tidak ada masalah pada sistem muskuloskeletal. Hal ini berarti postur kerja petani karet di CV. Eja Nursery dari tahap persiapan, pemanenan, pengangkutan hingga pemanenan masih kurang ergonomis. Perbaikan diperlukan adalah menyediakan alat bantu seperti meja dan kursi, perancangan alat bantu sadap, dan kereta dorong.
Pendampingan Stereotype Kesetaraan Gender di Masyarakat
Authors: Ramadina Evy 
Published: November 2022

Perkembangan teknologi yang semakin pesat seperti saat ini, masih ada masyarakat yang membedakan kesempatan peran perempuan dan laki-laki. Khususnya pada daerah-daerah tertinggal yang memiliki keterbatasan pengetahuan sehingga perempuan belum bisa berdaya secara penuh. Adanya diskriminasi ini disebabkan karena pemahaman kesetaraan gender belum berkembang merata pada masyarakat itu. Penyebab sulitnya menerapkan kesetaraan gender diantaranya budaya patriarki atau warisan turun temurun, pola asuh, posisi perempuan dalam keluarga, keseimbangan antara keluarga dan pekerjaan, dan pembatasan dalam organisasi. Diskriminasi peran perempuan dan laki-laki ini mempengaruhi perkembangan peradaban masyarakat. Perempuan bisa berkontribusi terhadap kemajuan suatu ekosistem tidak hanya laki-laki. Kebaruan pengetahuan pendidikan merupakan tanggungjawab bersama melalui peran dari setiap masyarakatnya. Untuk mengembalikan pemahaman yang belum merata terkait peran perempuan ini, salah satu upaya yang bisa dilakukan adalah mengadakan sosialisasi kesetaraan gender pada masyarakat. Sosialisasi ini diharapkan dapat membuka stigma positif masyarakat untuk menerapkan kesetaraan gender dalam kehidupan sehari-hari. Sehingga, masyarakat bisa berkerjasama dalam meningkatkan kesejahteraan masyarakat.
Association between soluble transferrin receptor and systolic hypertension in adults: National Health and Nutrition Examination Survey (2007–2010 and 2015–2018)
Authors: Wang Haoran , Qi Qianjin , Song Shuaihua , Zhang Di , Feng Li 
Published: November 2022

BackgroundHypertension increases the global burden of disease and mortality. Iron metabolism is considered to be an important factor in hypertension. However, as an indicator of iron metabolism, little is known about the associations of soluble transferrin receptor (sTfR) with hypertension. We studied the relationship between sTfR and hypertension.Materials and methodsWe studied 7,416 adults aged 20 years old or above from the National Health and Nutrition Examination Survey (NHANES), a nationally representative, cross-sectional, population-based study. Weighted logistic regression was used to examine the association between markers of iron metabolism and hypertension. The restricted cubic spline (RCS) was used to characterize the association between sTfR and blood pressure.ResultsWeighted logistic regression showed that higher sTfR level was associated with higher odds of hypertension (OR = 1.05; 95% CI: 1.01–1.05; p = 0.001) after adjustment for all the potential confounding factors. Meanwhile, weighted logistic regression analyses indicated independent associations of high sTfR (p = 0.009) with systolic hypertension after adjusting for various different confounders. The result of restricted cubic splines showed a non-linear association between sTfR and systolic blood pressure among U.S. adults.ConclusionSoluble transferrin receptor was found to be an independent factor in systolic hypertension. And, a non-linear relationship between sTfR and systolic blood pressure was discovered.
Multiscale entropy and small-world network analysis in rs-fMRI — new tools to evaluate early basal ganglia dysfunction in diabetic peripheral neuropathy
Authors: Yuan Geheng , Zheng Yijia , Wang Ye , Qi Xin , Wang Rui , Ma Zhanyang , Guo Xiaohui , Wang Xiaoying , Zhang Jue 
Published: November 2022

ObjectiveThe risk of falling increases in diabetic peripheral neuropathy (DPN) patients. As a central part, Basal ganglia play an important role in motor and balance control, but whether its involvement in DPN is unclear.MethodsTen patients with confirmed DPN, ten diabetes patients without DPN, and ten healthy age-matched controls(HC) were recruited to undergo magnetic resonance imaging(MRI) to assess brain structure and zone adaptability. Multiscale entropy and small-world network analysis were then used to assess the complexity of the hemodynamic response signal, reflecting the adaptability of the basal ganglia.ResultsThere was no significant difference in brain structure among the three groups, except the duration of diabetes in DPN patients was longer (p &lt; 0.05). The complexity of basal ganglia was significantly decreased in the DPN group compared with the non-DPN and HC group (p &lt; 0.05), which suggested their poor adaptability.ConclusionIn the sensorimotor loop, peripheral and early central nervous lesions exist simultaneously in DPN patients. Multiscale Entropy and Small-world Network Analysis could detect basal ganglia dysfunction prior to structural changes in MRI, potentially valuable tools for early non-invasive screening and follow-up.
Establishing a database for sickle cell disease patient mapping and survival tracking: The sickle pan-african research consortium Nigeria example
Authors: Nnodu Obiageli , Madu Anazoeze , Chianumba Reuben , Isa Hezekiah Alkali , Olanrewaju Isaac , Osagie Samuel , Oyekanmi Nash , Sangeda Raphael Zozimus , Stewart Annemie , Nembaware Victoria , Morrice Jack , Jonas Mario , Mazandu Gaston , Wonkam Ambroise , Owolabi Olumide 
Published: November 2022

Background: The Sickle Pan-African Research Consortium (SPARCO) and Sickle Africa Data Coordinating Center (SADaCC) were set up with funding from the US National Institute of Health (NIH) for physicians, scientists, patients, support groups, and statisticians to collaborate to reduce the high disease burden and alleviate the impact of Sickle Cell Disease (SCD) in Africa. For 5 years, SPARCO and SADaCC have been collecting basic clinical and demographic data from Nigeria, Tanzania, and Ghana. The resulting database will support analyses to estimate significant clinical events and provide directions for targeting interventions and assessing their impacts.Method: The Nigerian study sited at Centre of Excellence for Sickle Cell Disease Research and Training (CESRTA), University of Abuja, adopted REDCap for online database management. The case report form (CRF) was adapted from 1,400 data elements adopted by SPARCO sites. It captures 215 data elements of interest across sub-sites, i.e., demographic, social, diagnostic, clinical, laboratory, imaging, and others. These were harmonized using the SADaCC data dictionary. REDCap was installed on University of Abuja cloud server at https://www.redcap.uniabuja.edu.ng. Data collected at the sites are sent to CESRTA for collation, cleaning and uploading to the database.Results: 7,767 people living with sickle cell disease were enrolled at 25 health institutions across the six zones in Nigeria with 5,295 having had at least one follow-up visit with their clinical data updated. They range from 44 to 1,180 from 3 centers from South East, 4 from South, 5 from South West, 8 from North Central, 4 in North West and 3 in the North East. North West has registered 1,383 patients, representing 17.8%; North East, 359 (4.6%); North Central, 2,947 (37.9%); South West, 1,609 (20.7%); South, 442 (5.7%) and South East, 1,027 patients (13.2%).Conclusion: The database is being used to support studies including analysis of clinical phenotypes of SCD in Nigeria, and evaluation of Hydroxyurea use in SCD. Reports undergoing review in journals have relied on the ease of data access in REDCap. The database is regularly updated by batch and individual record uploads while we are utilizing REDCap’s in-built functions to generate simple statistic.
Mesenchymal stromal cell extracellular vesicles for multiple sclerosis in preclinical rodent models: A meta-analysis
Authors: Xun Chengfeng , Deng Huiyin , Zhao Jing , Ge Lite , Hu Zhiping 
Published: November 2022

IntroductionExtracellular vesicles (EVs), especially mesenchymal stem (stromal) cell-derived EVs (MSC-EVs), have gained attention as potential novel treatments for multiple sclerosis (MS). However, their effects remain incompletely understood. Thus, the purpose of this meta-analysis was to systematically review the efficacy of MSC-EVs in preclinical rodent models of MS.MethodsWe searched PubMed, EMBASE, and the Web of Science databases up to August 2021 for studies that reported the treatment effects of MSC-EVs in rodent MS models. The clinical score was extracted as an outcome. Articles were peer-reviewed by two authors based on the inclusion and exclusion criteria. This meta-analysis was conducted using Stata 15.1 and R.ResultsA total of twelve animal studies met the inclusion criteria. In our study, the MSC-EVs had a positive overall effect on the clinical score with a standardized mean difference (SMD) of -2.17 (95% confidence interval (CI)):-3.99 to -0.34, P = 0.01). A significant amount of heterogeneity was observed among the studies.ConclusionsThis meta-analysis suggests that transplantation of MSC-EVs in MS rodent models improved functional recovery. Additionally, we identified several critical knowledge gaps, such as insufficient standardized dosage units and uncertainty regarding the optimal dose of MSC-EVs transplantation in MS. These gaps must be addressed before clinical trials can begin with MSC-EVs.
Investigation of corrugated profiles in thin lossy dielectric slabs for wideband absorption up to 100 GHz
Authors: Huynen Isabelle 
Published: November 2022

The paper compares and optimizes through modeling conductive polymer composite slabs having different architectures of corrugated surfaces, designed to minimize both the reflectivity and its sensitivity to the angle of incidence of a microwave/millimeter wave signal impinging on the corrugated surface of the slab. Simulations using CST Studio software consider Poly-Lactid-Acid as dielectric material since it is widely used for 3D printing and offers very good possibilities of recycling in the frame of sustainability and green processing. Various profiles of corrugation are investigated; triangular, sinusoidal, or square-dot profiles, and compared with a uniform profile. Parameters such as height, width, and periodicity of the corrugations are varied in order to optimize the performances in terms of reflectivity over a large range of frequencies, between 20 GHz and 100 GHz. The configuration considered is the reflective screen, when the corrugated lossy dielectric slab covers a metallic plate mimicking the target. The goal is to maintain the reflectivity below 10 dB, in order to ensure up to 95% of absorption, for incidence angles up to 60°. Guidelines for the design and optimization of corrugated dielectric slab absorbers are proposed using specific gauges (Rozanov formalism and figure of merit) for the assessment of performances. Particular attention is devoted to the feasibility of manufacturing corrugated structures using additive 3D printing techniques.
The relationship between severe extracranial artery stenosis or occlusion and cerebral small vessel disease in patients with large artery atherosclerotic cerebral infarction
Authors: Dai Pei , Yu Hui-xian , Wang Zhao-xia , Liu Si-hao , Xu Guang-qing 
Published: November 2022

Background and purposeExtracranial artery stenosis (ECAS) is associated with the presence of individual markers of cerebral small vessel disease (CSVD). Here, we investigated the relationship between severe extracranial artery stenosis or occlusion and CSVD in patients with large artery atherosclerotic (LAA) cerebral infarction.MethodsA total of 128 patients with LAA cerebral infarction who met our specific inclusion criteria were selected, including 92 males and 36 females. These patients were divided into three groups based on whether they had severe symptomatic extracranial arterial stenosis or occlusion, severe asymptomatic extracranial artery stenosis or occlusion, or severe extracranial artery stenosis or occlusion (both symptomatic and asymptomatic). Intra-group comparisons were then performed to examine whether there were any differences in the total CSVD scores and Fazekas scores.ResultsPatients with severe extracranial arterial stenosis or occlusion and those with severe asymptomatic extracranial arterial stenosis or occlusion had a significantly higher total CSVD score (P &lt; 0.05), but there were no significant differences between the groups in terms of Fazekas scores. Furthermore, there were no significant difference in the total CSVD scores and Fazekas scores when compared between patients with or without severe symptomatic extracranial arterial stenosis or occlusion.ConclusionSevere stenosis or occlusion of the contralateral extracranial artery may increase the incidence of CSVD in patients with LAA cerebral infarction. Active and effective clinical intervention following comprehensive evaluation should be undertaken for unilateral cerebral infarction patients with severe stenosis or occlusion of the contralateral extracranial arterial.
Peri-procedure efficacy and safety of one-stop hybrid surgery for the treatment of brain arteriovenous malformations: A single-center preliminary experience
Authors: Fang Wei , Yang Zijian , Liu Yufeng , Yu Jia , Sun Peng , Zhao Zhenwei , He Yue , Zhang Tao , Deng Jianping 
Published: November 2022

BackgroundSome deficiencies and shortcomings in treatment strategies of brain arteriovenous malformation (bAVM) remain. It is worth exploring whether the one-stop hybrid surgical platform can play a positive role in the treatment of bAVM.ObjectiveThis study investigated short clinical and angiographic results of one-stop hybrid surgery for the treatment of bAVM.MethodsAll patients with bAVM treated with one-stop hybrid surgery were reviewed from February 2017 to December 2021. Data including demographic information, clinical conditions, characteristics of AVM, procedure details, and clinical and angiographic results were collected.ResultIn total, 150 cerebral bAVM patients received one-stop hybrid surgery; among them, 122 received surgical resection assisted by intraoperative DSA, and 28 were treated with combination surgical resection and endovascular embolization. Complete angiographic obliteration of the AVM was achieved in 136 patients (90.7%), and procedure-related death and neurological deficit rates were 7.3%. Of all relevant variables, logistic regression analysis showed that the Spetzler &amp; Martin (S&amp;M) score was the only factor related to the cure rate (P &lt; 0.001) and endpoint complication rate (P = 0.007).ConclusionsIn our preliminary experience, one-stop hybrid surgery for the treatment of brain AVMs achieves a high angiographic total occlusion rate, with acceptable peri-procedure morbidity and mortality. For S&amp;M 4 and 5 lesions, more cases and further study are needed to investigate the effects and safety of hybrid surgery.