bluuebunny/crossref_metadata_2025_split huggingface dataset:
Halloysite infused jute fiber/poly (3-hydroxy-butyrate-co-3-valerate) bionanocomposites: Thermal, mechanical and fire retardant properties
Authors: Hasan Kamrul SM , Zainuddin Shaik , Turner Azizi J , Hosur Mahesh V , Jeelani Shaik 
Published: September 2022

Biocomposites have become more mainstream over the past decades for preserving the environment and producing sustainable materials as a potential substitute to synthetic polymer based composites derived from scarce petroleum materials. However, it is essential to investigate their mechanical, thermal and fire retardancy performance to answer the question of their suitability in automobile, biomedical, construction, film packaging, and commercial industries. In this work, we have studied one such promising biocomposites, jute fiber/poly (3-hydroxy-butyrate-co-3-valerate) (PHBV) and investigated their aforementioned properties. At first, 3–15 wt% halloysite nanotubes (HNTs) were dispersed in PHBV/chloroform mixture using an ultrasound process. PHBV/HNTs thin films were then prepared using the solvent casting method. Finally, jute fiber/PHBV-HNTs bionanocomposites were prepared using the compression mold method. Thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC) tests were performed to study the thermal and fire retardancy properties. Uniaxial tensile and flexure tests were also performed to investigate the mechanical properties. In addition, scanning electron microscopy (SEM) was carried out to analyze the fracture surfaces of flexure tested samples. Results of jute/PHBV composites showed a significant increase in thermal and mechanical properties at 5 wt% HNTs loading in comparison to neat composites (without HNTs). In contrast, the composites with 15 wt% loading showed superior fire retardancy. SEM images of flexure tested samples showed enhanced interfacial bonding and less fiber pullout when compared to neat counterparts.
Bereaved Caregivers’ Experiences of End of Life Care For People With Advanced Heart Failure: A Narrative Synthesis
Authors: Diggle Melanie F. J. , Schutz Sue , Butcher Dan 
Published: September 2022

Background Heart Failure is a life-limiting condition with a poor and uniquely unpredictable prognosis. The aim of this review is to present and synthesise the current evidence around bereaved caregivers’ experiences of end of life care for people with Heart Failure. Methods A systematic review of the literature was conducted using four electronic databases (CINHAL, Medline, BND, PsycINFO). Data was analysed and presented using a narrative synthesis approach. Results Eight articles were included within this review. Themes included: Limited and inadequate communication around the condition (including prognosis, preparations for death and the aim of palliative care), the burden of caregiving, and the limited provision of services and formal support. Conclusion Bereaved caregivers experience unique and significant challenges when caring for someone dying from Heart Failure. However, further research is required to greater understand the experiences of bereaved caregivers of people with Heart Failure.
Relocation Later in Life and Contact Frequency With Friends: Do Contact Modes Matter?
Authors: Cho Joonyoung , Smith Jacqui 
Published: September 2022

We examined changes in the frequencies of in-person, telephone, and written or email contact with friends in older adults who move short or longer distances. 3820 adults aged 50 years or older were included from a nationally representative sample from the Health and Retirement Study. Using ordinal logistic regression, we found differential effects of geographical distances on the in-person, telephone, and write or email contact with friends. Specifically, in-person contact frequency was most sensitive to distance. Telephone contact frequency was only impacted by long-distance moves; however, email contact frequency was not influenced by distance. Findings suggest that the impact of relocation on contact frequency exists even though communication technology gives older adults flexibility in maintaining frequent contact with their friends. We discuss our findings through the lens of socioemotional selective theory and social convoy model. Future studies could examine factors linked to changes in the amount and modes of contact.
The Magnitude of Common Mental Disorders and Associated Factors Among Cancer Patients at Black Lion Specialized Hospital, Addis Ababa, Ethiopia: Cross- Sectional Study
Authors: Feyera Fetuma , Endeshaw Mulualem , Kebede Yigzaw , Tirfessa Kebede , Bekele Simeneh Belay 
Published: September 2022

Background Common mental disorders (CMD) are the most usual reactions following cancer diagnosis causing significant psychological sufferings. Even though research-based evidence is necessary for mental health promotion and intervention activities, there is a scarcity of evidence in Ethiopia to assist policy makers’ efforts in reforming mental health care particularly that of cancer patients. Objective The main objective of this research is to assess the magnitude of common mental disorders and associated factors among cancer patients who have a follow-up treatment at Black Lion Specialized Hospital, Addis Ababa, Ethiopia. Method Institutional-based cross-sectional study was conducted from August 1 to September 30, 2020. A systematic random sampling technique was used to select 396 study participants. A Self-Reporting Questionnaire (SRQ-20) and interviewer-administered structured questionnaire were employed to collect data. Data were analyzed using descriptive statistics and logistic regression. Odds ratios with 95% confidence intervals was used to report the findings. Result A total of 396(230 men and 160 women) participants took part in the study. The overall magnitude of CMD among cancer patients was found to be 70.3%, of which the rate was 73.5% among women and 67.8% among men, in the last 4 weeks. Being women (AOR = 1.74; 95%CI: 1.00, 3.02), unemployed (AOR = 3.035, 95% CI: 1.37, 6.72), average monthly income of less than 1600 Ethiopian Birr (AOR = 2.838; 95%CI: 1.58, 5.08), being on cancer treatment for more than 5 years (AOR = 2.653, 95% CI: 1.39, 5.03), poor social support (AOR = 3.618, 95% CI: 1.33, 9.80), and current use of substances (AOR = 6.852; 95% CI: 2.038, 23.034) were the factors significantly associated with CMD. Conclusion and recommendation Common mental disorders are one of the major health concerns among cancer patients. Common mental disorders were found to be more common in females and among current users of a psychoactive substance. Therefore, cancer patients need special attention of not only physicians but also that of mental health professionals for possible detection and early treatment of mental disorders. Rendering social and economic support may reduce the negative effects of the illness.
The Effect of Positive Psychotherapy-Based Training on Stigma and Self-Efficacy in Women Receiving Infertility Treatment
Authors: Yanık Derya , Kavak Budak Funda 
Published: September 2022

Background: Infertility has increased in recent years. Infertility can cause many mental problems. The place of psychoeducation based on positive psychotherapy (PPT) is important in coping with mental problems. Aims: The aim of this study is to determine the effect of PPT-based training on stigma and self-efficacy in women receiving infertility treatment. Methods: This experimental study with randomized control group was completed with 64 women receiving infertility treatment. While the women in the experimental group received an 8-session PPT-based training, no intervention was applied to those in the control group. Results: A statistically significant difference was observed ( p= .001) between the stigma and self-efficacy levels of the experimental group after the PPT-based training. Conclusions: It was found that the PPT-based training was effective in decreasing stigma level of the women who received infertility treatment and increasing their self-efficacy level.
Influences of COVID-19 pandemic and the states of emergency on occupational therapy for physical disorders: A questionnaire survey in Hokkaido, Japan
Authors: Saito Hidekazu , Yokoyama Kazuki , Morimoto Takafumi , Ota Hisaaki , Ikeda Nozomu 
Published: September 2022

Objective: This study aimed to explore the influence of coronavirus disease-2019 (COVID-19) on occupational therapy (OT) for physical disorders, including changes in the assessment, treatment, other restrictions, and measures of OT. Methods: A questionnaire survey was conducted among occupational therapists working in Hokkaido, Japan, and 123 out of the 334 (36.8%) were from OT facilities that target physical disorders. The responses were classified the categories and codes by [ ] and < >, respectively. Results: The number of patients decreased in 47.1% of the OT facilities after the pandemic declaration. Only one facility reported <decrease in intervention with palpation>. Therefore, [thoroughness of standard precautions] including <disinfection of materials and common use areas>, <hand hygiene>, and [changes in treatment structure] including <restriction on use of materials> were implemented. Additionally, there were not only [restrictions on participation of patients] and [restrictions on outpatient services], but also [restrictions on operations of OT], such as <cancellation or change of the methods of meetings and workshops> and so on. Furthermore, [changes in treatment structure] and [setting criteria for discontinuation of participation] were utilized in some facilities to prevent and to reduce the risk of infection. Conclusions: By revisiting the assessment and treatment guidelines on infection control, it is possible to provide continuous OT services and to tackle the challenges posed by the pandemic.
Effects of a postoperative program in patients with shoulder stiffness following arthroscopic rotator cuff repair
Authors: Gutiérrez-Espinoza Héctor , Araya-Quintanilla Felipe , Pinto-Concha Sebastián , Sepúlveda-Loyola Walter , Ramírez-Vélez Robinson , Fuentes-Contreras Jorge 
Published: September 2022

Background The most common complication in the surgery for rotator cuff (RC) tears is postoperative shoulder stiffness. The evidence for the postoperative treatment of this condition is scarce. This study assessed the effects of a postoperative program at the onset of shoulder stiffness following arthroscopic RC repair. Methods A single-group pre- and post-test design was included. Participants performed a 6-week program. Primary outcomes were shoulder and upper limb function assessed with the Constant–Murley and Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaires, respectively. Secondary outcomes included pain intensity at rest and during movement with the visual analog scale (VAS), and shoulder range of motion assessed with a goniometer. Results A total of 115 adult males were included. The intervention produced a positive effect on the Constant–Murley (+35.6 points, p<0.001) and DASH questionnaire (−26.2 points, p = 0.005); VAS at rest (−2.8 cm, p<0.001); VAS at movement (−2.7 cm, p<0.001); and shoulder ROMs. Conclusion The program showed clinically and statistically significant benefits in most of the functional outcomes in the study participants.
Hip Labral Reconstruction With a Polyurethane Scaffold: Restoration of Femoroacetabular Contact Biomechanics
Authors: Capurro Bruno , Reina Francisco , Carrera Anna , Monllau Joan Carles , Marqués-López Fernando , Marín-Peña Oliver , Torres-Eguía Raúl , Tey-Pons Marc 
Published: September 2022

Background: Many advances have been made in hip labral repair and reconstruction and in the restoration of the suction seal. Purpose/Hypothesis: The purpose of this study was to evaluate the biomechanical effects of segmental labral reconstruction with a synthetic polyurethane scaffold (PS) in comparison with segmental labrectomy. Our hypothesis was that reconstruction with a icroporous polyurethane implant would normalize joint kinetics of the hip and restore the suction seal. Study Design: Controlled laboratory study. Methods: We used 10 hips from 5 fresh-frozen pelvises with an intact acetabular labrum without osteoarthritis. Using an intra-articular pressure measurement system, the contact area, contact pressure, and peak force were assessed for the following conditions: intact labrum, partial anterosuperior labrectomy, and PS reconstruction. For each condition, all specimens were analyzed in 4 positions (90° of flexion, 90° of flexion and internal rotation, 90° of flexion and external rotation, and 20° of extension) and underwent a labral seal test. The relative change from the intact condition was determined for all conditions and positions. Results: Compared with the intact labrum, labrectomy resulted in a significant decrease in the contact area ( P < .001) and a significant increase in the peak force ( P < .001) and contact pressure ( P < .001) across all positions. Compared with labrectomy, PS reconstruction resulted in a significant increase in the contact area ( P < .001) and a significant decrease in the contact pressure ( P ≤ .02) and peak force ( P < .001) across all positions. Compared with the intact labrum, PS reconstruction restored the contact area and peak force to normal values in all positions ( P > .05), whereas the contact pressure was significantly decreased compared with labrectomy ( P < .05) but did not return to normal values. The labral seal was lost in all specimens after labrectomy but was restored in 80% of the specimens after PS reconstruction. Conclusion: Femoroacetabular contact biomechanics significantly worsened after partial labrectomy; reconstruction using a PS restored the contact area and peak force to the intact state and improved the contact pressure increases seen after partial labrectomy. The contact area and peak force were normalized, and the labral seal was re-established in most cases. Clinical Relevance: This study provides biomechanical evidence for the use of a scaffold for labral reconstruction.
Effect of Anterior Horn Tears of the Lateral Meniscus on Knee Stability
Authors: Shiwaku Kousuke , Kamiya Tomoaki , Otsubo Hidenori , Suzuki Tomoyuki , Nabeki Shogo , Yamakawa Satoshi , Okada Yohei , Teramoto Atsushi , Watanabe Kota , Iba Kousuke , Fujie Hiromichi , Yamashita Toshihiko 
Published: September 2022

Background: Investigations on the biomechanical characteristics of the anterior horn of the lateral meniscus (AHLM) related to anterior cruciate ligament (ACL) tibial tunnel reaming have revealed increased contact pressure between the femur and tibia, decreased attachment area, and decreased ultimate failure strength. Purpose/Hypothesis: The purpose of this study was to investigate the influence of a complete radial tear of the AHLM on force distribution in response to applied anterior and posterior drawer forces and internal and external rotation torques. We hypothesized that the AHLM plays an important role in knee stability, primarily at lower knee flexion angles. Study Design: Controlled laboratory study. Methods: A total of 9 fresh-frozen cadaveric knee specimens and a robotic testing system were used. Anterior and posterior drawer forces up to 89 N and internal and external rotation torques up to 4 N·m were applied at 0°, 30°, 60°, and 90° of knee flexion. A complete AHLM tear was then made 10 mm from the lateral border of the tibial attachment of the ACL, and the same tests performed in the intact state were repeated. Next, the recorded intact knee motion was reproduced in the AHLM-torn knee, and the change in the resultant force after an AHLM tear was determined by calculating the difference between the 2 states. Results: In the torn AHLM, the reduction in the resultant force at 0° for external rotation torque (34.8 N) was larger than that at 60° (5.2 N; P < .01) and 90° (6.7 N; P < .01). Conclusion: The AHLM played a role in facilitating knee stability against an applied posterior drawer force of 89 N and external rotation torque of 4 N·m, especially at lower knee flexion angles. Clinical Relevance: This study provides information about the effects of AHLM injuries that may occur during single-bundle ACL reconstruction using a round tunnel.
O-GlcNAcylation: an important post-translational modification and a potential therapeutic target for cancer therapy
Authors: Lu Qingsong , Zhang Xiaozhen , Liang Tingbo , Bai Xueli 
Published: September 2022

AbstractO-linked β-d-N-acetylglucosamine (O-GlcNAc) is an important post-translational modification of serine or threonine residues on thousands of proteins in the nucleus and cytoplasm of all animals and plants. In eukaryotes, only two conserved enzymes are involved in this process.O-GlcNAc transferase is responsible for addingO-GlcNAc to proteins, whileO-GlcNAcase is responsible for removing it. AberrantO-GlcNAcylation is associated with a variety of human diseases, such as diabetes, cancer, neurodegenerative diseases, and cardiovascular diseases. Numerous studies have confirmed thatO-GlcNAcylation is involved in the occurrence and progression of cancers in multiple systems throughout the body. It is also involved in regulating multiple cancer hallmarks, such as metabolic reprogramming, proliferation, invasion, metastasis, and angiogenesis. In this review, we first describe the process ofO-GlcNAcylation and the structure and function ofO-GlcNAc cycling enzymes. In addition, we detail the occurrence ofO-GlcNAc in various cancers and the role it plays. Finally, we discuss the potential ofO-GlcNAc as a promising biomarker and novel therapeutic target for cancer diagnosis, treatment, and prognosis.
Genome-wide characterization of the MBF1 gene family and its expression pattern in different tissues and stresses in Zanthoxylum armatum
Authors: Hui Wenkai , Zheng Hao , Fan Jiangtao , Wang Jingyan , Saba Tahseen , Wang Kai , Wu Jiaojiao , Wu Han , Zhong Yu , Chen Gang , Gong Wei 
Published: September 2022

Abstract
Background
Multiprotein bridging factor 1 (MBF1) is a crucial transcriptional coactivator in animals, plants, and some microorganisms, that plays a necessary role in growth development and stress tolerance. Zanthoxylum armatum is an important perennial plant for the condiments and pharmaceutical industries, whereas the potential information in the genes related to stress resistance remains poorly understood in Z. armatum.

Results
Herein, six representative species were selected for use in a genome-wide investigation of the MBF1 family, including Arabidopsis thaliana, Oryza sativa, Populus trichocarpa, Citrus sinensis, Ginkgo biloba, and Z. armatum. The results showed that the MBF1 genes could be divided into two groups: Group I contained the MBF1a and MBF1b subfamilies, and group II was independent of the MBF1c subfamily.. Most species have at least two different MBF1 genes, and MBF1c is usually an essential member. The three ZaMBF1 genes were respectively located on ZaChr26, ZaChr32, and ZaChr4 of Zanthoxylum chromosomes. The collinearity were occurred between three ZaMBF1 genes, and ZaMBF1c showed the collinearity between Z. armatum and both P. trichocarpa and C. sinensis. Moreover, many cis-elements associated with abiotic stress and phytohormone pathways were detected in the promoter regions of MBF1 of six representative species. The ERF binding sites were the most abundant targets in the sequences of the ZaMBF1 family, and some transcription factor sites related to floral differentiation were also identified in ZaMBF1c, such as MADS, LFY, Dof, and AP2. ZaMBF1a was observed to be very highly expressed in 25 different samples except in the seeds, and ZaMBF1c may be associated with the male and female floral initiation processes. In addition, expression in all the ZaMBF1 genes could be significantly induced by water-logging, cold stress, ethephon, methyl jasmonate, and salicylic acid treatments, especially in ZaMBF1c.

Conclusion
The present study carried out a comprehensive bioinformatic investigation related to the MBF1 family in six representative species, and the responsiveness of ZaMBF1 genes to various abiotic stresses and phytohormone inductions was also revealed. This work not only lays a solid foundation to uncover the biological roles of the ZaMBF1 family in Z. armatum, but also provides some broad references for conducting the MBF1 research in other plants.
Acceptability of injectable pre-exposure prophylaxis among people who inject drugs in three urban U.S. settings
Authors: King Adrian R. , Shah Saanchi , Randall Laura A. , Frew Paula M. , Spaulding Anne ,   HBOU Study Team, Holloway Ian W. 
Published: September 2022

Abstract
Background
Outbreaks of new HIV transmission among people who inject drugs (PWID) are a major public health concern. Oral daily PrEP, has been identified as a critical addition to the biomedical toolkit for this population. However, limited research on the acceptability of long-acting injectable PrEP has been conducted with this population.

Methods
We conducted a cross sectional multi-site survey with 1127 participants from May 2019–February 2020 to assess the acceptability of novel PrEP regimens. We computed bivariate and multivariable logistic regressions to evaluate correlates of the outcome variable: acceptability of 3-month injectable-PrEP. SAS v.9.4 was used to conduct statistical analysis.

Results
Limited knowledge of or use of PrEP, past or present, was evident within the sample. Injection drug use in the past six months was significantly associated with LA injectable PrEP acceptability, with the odds of acceptability being 1.885 (CI: 1.376, 2.582) times greater than those who did not inject drugs. After adjusting for confounders, injection drug use was significantly associated with the outcome, such that the odds of acceptability of LA injectable PrEP were 1.705 (CI: 1.198, 2.427) times greater among PWID compared to those who did not inject drugs (p < 0.03). The results demonstrate acceptability (38.2%) in a durable (3-month) injectable PrEP modality among participants who also identified as PWID.

Conclusions
PrEP promotion efforts among PWID to increase access to long-acting injectable PrEP are necessary. Through efforts to increase acceptance and regular use of long-acting injectable PrEP, public health strategies may be able to effectively lessen chances of future HIV outbreaks among PWID.
Response to SARS-CoV-2 vaccines in patients receiving B-cell modulating antibodies for renal autoimmune disease
Authors: Arnold Frederic , Huzly Daniela , Tanriver Yakup , Welte Thomas 
Published: September 2022

Abstract
Background
Effective SARS-CoV-2 vaccination in patients receiving treatment with B-cell depleting agents is challenging. Information on vaccination responses in these patients are a valuable tool to develop efficient vaccination regimens.

Methods
In this single-center retrospective observational study, we report the humoral and cellular response in 34 patients receiving anti-CD20 antibody treatment for renal immune disease.

Results
After base immunization with SARS-CoV-2-vaccines, 92.0% developed a cellular, 32.4% a humoral response. Humoral immunity correlated with B-cell counts and the timespan between anti-CD20 antibody treatment and vaccination. All patients with > 21/µl B-cells, or > 197 days after treatment showed humoral response.

Conclusions
Adequate timing of SARS-CoV-2-vaccinations after anti-CD20 antibody treatment and CD19 measurements are crucial to generate immunity. Awaiting partial B-cell recovery by postponing regularly scheduled anti-CD20 treatment should be considered in patients with stable immune disease.
Trial registration: This study has been retrospectively registered in the German Clinical Trials Register (DRKS00027049) on 29/10/2021.