bluuebunny/crossref_metadata_2025_split huggingface dataset:
EVALUATION OF MICROBIOLOGICAL CONTAMINATION PARAMETERS OF TRADITIONAL MEDICINAL PREPARATIONS CONTAINING RED GINGER
Authors: PRATAMI DIAH KARTIKA , KUMALA SHIRLY , WIDYASIH I GUSTI NYOMAN ARY , MIFTAHURROHMAH NUR , NAFISA SAFIRA 
Published: July 2022

Objective: The purpose of this study was evaluated the presence or absence of pathogenic microbial contamination in traditional medicinal preparations containing red ginger based on specific microbial tests and evaluating the amount of microbial contamination in traditional medicinal preparations containing red ginger based on the Total Plate Number and Mold Yeast values.
Methods: This research was conducted on instant powdered herbal preparations containing red ginger and internal medicinal liquid containing red ginger. This preparation will be tested for safety and quality requirements including Total Plate Number with Tryptic Soy Agar media, Yeast Mold Number with Saboroud Dextrose Agar media, Enterobacteriaceae Numbers with Violet Red Bile Glucose media, Escherichia coli with Mac Conkey Agar media, Clostridia sp with Reinforced media Medium for Clostridia, Salmonella sp with Rappaport Vasiliadis medium Salmonella Enrichment Broth, and Shigella sp with Xylose Lysine Deoxycholate Agar.
Results: The results of the study for the Total Plate Count and Mold and Yeast values ​​in red ginger instant powder preparations were<10 CFU/gr, for testing the microbes Escherichia coli, Salmonella sp., Clostridia, and Shigella sp. is negative. Then, the results of the research on the medicinal liquid in red ginger for microbial contamination values ​​were<10 CFU/gr, for testing Escherichia coli, Salmonella sp., Clostridia, and Shigella sp. is negative/gr.
Conclusion: Based on the results obtained, it is concluded that herbal preparations containing red ginger meet the safety and quality requirements so that they are safe for consumption.
THE FORMULATION OF NANOEMULSION SERUM-CONTAINING GOTU KOLA EXTRACT (CENTELLA ASIATICA L. URBAN) AND CHIA SEED OIL (SALVIA HISPANICA) FOR SKIN HYDRATION EFFECT
Authors: KARLINA SELLY , CHAIDIR  , FARIDA YUNAHARA 
Published: July 2022

Objective: The aims of this study of nano serum formulation from C. asiatica and chia seed to skin hydration effect.
Methods: C. asiatica extraction was macerated by 70% ethanol and evaporated by a rotary evaporator to produce high viscosity of extract yields. Four different formulas were obtained from nanoemulsion serum production with different concentrations of chia seed oil (1%, 2%, 3%, 4%). Two formulas F1 (1% chia seed oil) and F4 (4% chia seed oil) were selected for further clinical testing, which were applied at face skin for 7 d, then were measured using a skin analyzer looking for the best and most effective.
Results: Optimation result of extraction method of C. asiatica herb as high as 28.74% extract yields and 3.12% asiaticoside content. The result value of formulation based on the effect of moisturizing/hydration then can be analyzed with the Minitab program using the One-way ANOVA method. The result indicated that the product can increase face skin moistness at 20 respondents, where 13.36% increase from F1 formula and 13.88% increase from F4 formula.
Conclusion: The nanoemulsion serum-containing combination of C. asiatica extract and chia seed oil enables to increase in the moisturizing effect on dry skin or normal tend to dry skin.
FORMULATION AND EVALUATION OF CITRONELLA OIL IN ROLL-ON APPLICATION SYSTEM
Authors: NAFISA SAFIRA , KUMALA SHIRLY , SUMIYATI YATI , WINARTI WIWI , PRATAMI DIAH KARTIKA , AULENA DESI NADYA , YANTIH NOVI , NURSAFITRI AMELIA 
Published: July 2022

Objective: The purpose of this study to obtain the best formulation of roll-on Citronella oil that can be used for aromatherapy.
Methods: The citronella plant (Cymbopogon winterianus Jowitt) was processed with Steam-water distillation produced essential oil. Citronella oil was tested for quality and formulated. The best formulation result is then tested for product quality.
Results: The result of yield of citronella oil was 0.6%. The result of citronella oil quality parameters is obtained in accordance with the literature. The result of the hedonic test, formula 2 was chosen to be the best formula. The result of an average transferred volume was 10.0 ml. The result of the total plate number is<`10 cfu/ml. The result of the identification of Staphylococcus aureus and Pseudomonas aeruginosa was negative. The result of the stability test was stable during storage.
Conclusion: The results showed that formula 2 was the best and has the potential to be circulated in large quantities
FORMULATION AND EVALUATION OF RED GINGER OIL (ZINGIBER OFFICINALE ROSCOE) BALM AS AN ANALGESIC
Authors: SUMIYATI YATI , NAFISA SAFIRA , WINARTI WIWI , MUMPUNI ESTI , PRATAMI DIAH KARTIKA , AULENA DESI NADYA , YANTIH NOVI , JOTI  
Published: July 2022

Objective: The purpose of this study was to obtain the best formulation of red ginger oil balm that can be used for aromatherapy as an analgesic.
Methods: The red ginger plant in Steam-water distillation produces red ginger oil. Red ginger oil is tested for quality and formulated. The best formulation result is then tested for product quality.
Results: The result of red ginger oil quality parameters is obtained in accordance with the literature. As the result of the hedonic test, formula 4 was chosen to be the best formula. The result of the total plate number is<`10 CFU/ml. The result of the identification of Staphylococcus aureus and Pseudomonas aeruginosa is negative. The result of the stability test, irritation tests, and pH test was stable during storage.
Conclusion: The results showed that formula 4 is the best formula and has the potential to circulate in large quantities.Red ginger oil
MICROENCAPSULATION OF INDONESIAN POLYMER BIODIVERSITY IN WARTHON'S JELLY MESENCHYMAL STEM CELL (WJMSC)
Authors: RAHMAT DENI , WIDOWATI WAHYU , FARIED AHMAD , NAINGGOLAN ITA MARGARETHA , PRIYANDOKO DIDIK , BUDIATI ANARISA , ZAKARIA TEDDY MARCUS , AFIFAH ERVI 
Published: July 2022

Objective: WJMSC is a stem cell-derived from Wharton's Jelly the umbilical cord of pregnant women which has the ability to differentiate into other cells that are osetogenic, myogenic, neurogenic, and hematopoietic. Stem cell microencapsulation is a cell coating technique that is expected to act as a delivery vehicle. This study aims to make stem cell microencapsulation using various types of natural polymers.
Methods: WJMSC (Wharton's Jelly Mesenchymal Stem Cell) was cultured with supplemented Modified Eagle Medium (MEM) Alpha in incubator with 37 °C and 5% of CO2. In this study, we investigated various of natural polymers (chitosan, glucomannan, inulin, fucoidan and amylopectin) in WJMSC microencapsulation. Viability cell of WJMSC microencapsulate was measured using MTS (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxy-phenyl)-2-(4-sulfophenyl)-2H-tetrazolium) assay, and the condition medium (CM) was determined the measure EGF, IL-6, VEGF with ELISA.
Results: WJMSC microencapsulation using chitosan, oxidized glucomannan, inulin, fucoidan and oxidized amylopectin showed viability cell up to 100%. The EGF, IL-6, VEGF levels were increased in all tested polymers compared to negative control.
Conclusion: Tested polymers (chitosan, oxidized glucomannan, inulin, fucoidan, oxidized amylopectin) were not toxic to WJMSC and cell microencapsulation was successfully carried out.
QUALITY PARAMETERS AND DETERMINATION OF TOTAL FLAVONOID LEVELS FROM THE HIGHEST ANTIOXIDANT ACTIVITY OF ETHANOL 70% EXTRACT JACKFRUIT PEEL (ARTOCARPUS HETEROPHYLLUS L.) BY MACERATION, REFLUX, AND ULTRASONIC METHODS
Authors: FARIDA YUNAHARA , QODRIAH RAHMATUL , NILESH SANAM 
Published: July 2022

Objective: The aim of this study was to investigate and determination of total flavonoid levels antioxidant activity of ethanol 70% extract jackfruit peel (Artocarpus heterophyllus L.) by maceration, reflux, and ultrasonic methods
Methods: Jackfruit peel was extracted by using maceration, reflux, and ultrasonic methods with 70% of ethanol as the solvent. Antioxidant activity using DPPH free radical scavenging and determination of total flavonoid levels using colorimetric methods.
Conclusion: The results of phytochemical screening indicates that jackfruit peel contains flavonoids, saponins, tannin, and triterpenoids; the best antioxidant activity is found in the maceration method. The extract of Jackfruit peel fullfill the quality parameters requirements.
Results: The determination was carried out at the Center for Plant Conservation and Botanical Gardens-LIPI, Bogor. The results of this determination indicate that the material studied belongs to the species Artocarpus heterophyllus L.
THE ROLE OF PROPOLIS TETRAGONULA SP. IN OXIDATIVE STRESS AND ITS PROTECTIVE EFFECT AGAINST UV RADIATION ON CELLS
Authors: ASIH SAFIRA CANDRA , PRATAMI DIAH KARTIKA , YOHDA MASAFUHMI , FUKUTAMI YOSUKE , FARIED AHMAD , SAHLAN MUHAMAD 
Published: July 2022

Objective: This report presents a study the anti-oxidant properties of propolis wax from Tetragonula sp. bees by evaluating the protection ability of propolis towards cells from ultraviolet (UV) exposure. The next evaluation was using a literature study and LC-MS (Liquid Chromatography-Mass Spectrometry) to find compounds in propolis that are responsible for anti-oxidative stress activity.
Methods: HEK 293T (Human Embryonic Kidney 293 T) and fibroblast cells line were used. Four tests were performed on the cells, namely: cell proliferation assay using water-soluble tetrazolium salt (WST-8); lactate dehydrogenase (LDH), and free radicals produced on cells test by measuring fluorescence intensity produced by dichlorofluorescein; cell viability through observation using fluorescence microscope on cells stained with Hoechst and propidium iodide (PI); and reactive oxygen assay (ROS) Assay. Before UV exposure, propolis wax was added to the cells in different concentrations. The authors also analyzed the component in propolis wax using LC-MS.
Results: Based on this assessment, it was found that propolis wax successfully protects the cells against UV-induced free radicals’ formation by maintaining the cell proliferation rate, reducing the free radicals produced after UV exposure, and decreasing the number of cell death. Nevertheless, we found that a greater concentration of propolis wax tends to be toxic to the cells. While on the LC-MS results obtained about 83 compounds, in which 35 of them are flavonoid and polyphenols derived compounds with antioxidant properties.
Conclusion: Based on these findings, propolis wax produced Tetragonula sp. can be used as a potential alternative treatment of anti-oxidative stress and anti-free radicals.
PEMBERDAYAAN MASYARAKAT MELALUI BANK SAMPAH BERKAH JAYA PLASTINDO OLEH DINAS LINGKUNGAN HIDUP KABUPATEN KOTAWARINGIN BARAT
Authors: Mustafirin Mustafirin , Riyadi Agus , Saputri Jihan Irwana 
Published: July 2022

Abstract: This study aims to determine the empowerment process and the impact of the Induk Berkah Jaya Plastindo Waste Bank. The method used in this research is descriptive qualitative with a sociological approach where the researcher focuses and describes a variable related to the problem under study. Data collection techniques in the study used observation, interviews, and documentation, then data validity and data analysis were carried out. The results of this study are the community empowerment process carried out by the Berkah Jaya Plastindo Waste Bank as the main waste bank that can be seen through three stages, namely the awareness stage and the behavior formation stage, the knowledge transformation stage, the intellectual ability improvement stage and the impact of community empowerment through the Waste Bank. Parent Berkah Jaya Plastindo is able to increase the community's economic income, a clean and healthy environment, the emergence of high solidarity, and being able to become an inspiration for other waste banks.Keywords: Community Empowerment, Jaya Plastindo Berkah Waste Bank, Environmental Service.Abstrak: Penelitian ini bertujuan untuk mengetahui proses pemberdayaan dan dampak dari Bank Sampah Induk Berkah Jaya Plastindo. Metode yang digunakan dalam penelitian ini adalah kualitatif deskriptif dengan pendekatan sosiologis di mana peneliti fokus dan menggambarkan suatu variabel yang berkenaan dengan masalah yang diteliti. Teknik pengumpulan data dalam penelitian menggunakan observasi, wawancara, dan dokumentasi selanjutnya dilakukan validitas data, dan analisis data. Hasil dari penelitian ini yaitu proses pemberdayaan masyarakat yang dilakukan oleh Bank Sampah Induk Berkah Jaya Plastindo sebagai bank sampah induk dapat dilihat melalui tiga tahap yaitu tahap penyadaran dan tahap pembentukan perilaku, tahap transformasi pengetahuan, tahap peningkatan kemampuan intelektual dan dampak dari pemberdayaan masyarakat melalui Bank Sampah Induk Berkah Jaya Plastindo yakni mampu menambah pendapatan ekonomi masyarakat, lingkungan yang bersih dan sehat, timbulnya solidaritas yang tinggi, dan mampu menjadi inspirasi bank sampah lainnya.Kata Kunci: Pemberdayaan Masyarakat, Bank Sampah Berkah Jaya Plastindo, Dinas Lingkungan Hidup.
STRATEGI PEMBINAAN DALAM MENANAMKAN NILAI-NILAI RELIGIUS PADA MUALAF ETNIS TIONGHOA DI ORGANISASI PERSATUAN ISLAM TIONGHOA INDONESIA (PITI) SURABAYA
Authors: Hidayatulloh Dedi 
Published: July 2022

Abstract: This research is based on religious phenomena that occur in Indonesia, especially regarding religious conversion. The religious conversion is dominated by other religions who want to embrace Islam, where the majority of religious conversions occur in the ethnic Chinese environment. The Indonesian Chinese Islamic Association (PITI) in Surabaya is one of the institutions that oversees the development of converts to Islam and has a special strategy in fostering converts, especially the Chinese. This research is a qualitative research with a case study approach to determine the strategy of converting converts in the Indonesian Chinese Islamic Association Organization (PITI) Surabaya. Collecting data in this research is observation, interview and documentation. This study aims to answer, describe and analyze the problem of general description regarding the strategy of fostering ethnic Chinese converts at the Indonesian Chinese Islamic Association (PITI) Surabaya. The results showed that the general description of the strategies applied in instilling religious values in fostering ethnic Chinese converts to the Chinese Indonesian Islamic Association Organization (PITI) Surabaya included: 1) teaching; 2) habituation; 3) exemplary; 4) motivation; and 5) regulations.Keywords: Development Strategy; Chinese Ethnic Converts; PITI Surabaya.Abstrak: Penelitian ini didasarkan pada fenomena agama yang terjadi di Indonesia terkhusus perihal konversi agama. Konversi agama tersebut didominasi oleh agama lain yang ingin memeluk agama Islam, di mana perpindahan agama tersebut mayoritas terjadi di lingkungan etnis Tionghoa. Persatuan Islam Tionghoa Indonesia (PITI) Surabaya merupakan salah satu lembaga yang menaungi pembinaan mualaf dan memiliki strategi khusus dalam membina mualaf terkhusus etnis Tionghoa. Penelitian ini merupakan penelitian kualitatif dengan pendekatan studi kasus untuk mengetahui strategi pembinaan mualaf di Organisasi Persatuan Islam Tionghoa Indonesia (PITI) Surabaya. Pengumpulan data dalam penelitian ini adalah observasi, wawancara dan dokumentasi. Penelitian ini bertujuan untuk menjawab, mendeskripsikan serta menganalisis permasalahan gambaran umum mengenai strategi pembinaan mualaf etnis Tionghoa di Persatuan Islam Tionghoa Indonesia (PITI) Surabaya. Hasil penelitian menunjukkan temuan bahwa gambaran umum mengenai strategi yang diterapkan dalam menanamkan nilai-nilai religius membina mualaf etnis Tionghoa di Organisasi Persatuan Islam Tionghoa Indonesia (PITI) Surabaya meliputi: 1) pengajaran; 2) pembiasaan; 3) keteladanan; 4) motivasi; dan 5) peraturan.Kata Kunci: Strategi Pembinaan; Mualaf Etnis Tionghoa; PITI Surabaya.
HAKIKAT DAN TUJUAN PERNIKAHAN DI ERA PRA-ISLAM DAN AWAL ISLAM
Authors: Januario Ridwan Angga , Sj Fadil , Thoriquddin Moh. 
Published: July 2022

Abstract: Marriage is a sacred event experienced by a man and a woman. According to the marriage, there is inner and outer peace, but looking at the historical facts, especially in the pre-Islamic era, women did not get a favorable position at that time. Which is influenced by the socio-cultural society that adheres to a patriarchal system. So, that men monopolize all matters related to family matters. This results in inequality in social life. The existence of a marriage tradition rooted in the patriarchal system, resulted in the marriage being like a sale and purchase contract, where women became the object of merchandise. From the results of the study it was found that in the pre-Islamic era, the nature of marriage was something that was natural and cultural. Meanwhile, the purpose of marriage is only to obtain offspring and satisfy lust. As long as for the Islamic era, the nature of marriage is something that is instinctive and the law is regulated by religion. With the result that marriage is intended to worship, find happiness, produce offspring, and vent lust.Keywords: Marriage; Pre-Islamic; Early Islam.Abstrak: Pernikahan merupakan suatu peristiwa sakral yang dialami oleh pasangan pria dan wanita. Yang mana dengan adanya pernikahan tersebut, maka diperoleh ketenteraman lahir dan batin, Namun melihat fakta sejarah yang ada, terlebih di era pra Islam, maka perempuan tidaklah mendapatkan posisi yang menguntungkan kala itu. Yang mana hal tersebut terpengaruh oleh sosio kultural masyarakat yang menganut sistem patriarki. Sehingga pria memonopoli segala urusan terkait dengan masalah keluarga. Hal ini mengakibatkan adanya ketidaksetaraan di dalam kehidupan sosial bermasyarakat. Adanya tradisi perkawinan yang mengakar pada sistem patriarki, mengakibatkan pernikahan tersebut tak ubahnya sebagai kontrak jual beli, di mana wanita menjadi obyek barang dagangan. Dari hasil penelitian didapati bahwa pada era pra-Islam, hakikat pernikahan adalah sesuatu yang sifatnya alamiah dan kultural. Sedangkan tujuan pernikahan hanya semata untuk memperoleh keturunan dan memuaskan syahwat. Adapun pada masa Islam, hakikat pernikahan adalah sesuatu yang sifatnya naluriah dan hukum yang diatur oleh agama. Sedangkan pernikahan ditujukan untuk beribadah, mendapatkan kebahagiaan, memperoleh keturunan, dan melampiaskan syahwat.Kata Kunci: Pernikahan; Pra Islam; Awal Islam.
PERKAWINAN TRANSEKSUAL PERSPEKTIF TEORI HAK KODRATI
Authors: Auliyak Waro Satul , Sumbulah Umi , Suwandi Suwandi 
Published: July 2022

Abstract: Along with the development of the times, some individuals perform sex reassignment surgery because they feel that their current body is not following their psyche. Individuals who perform sex reassignment surgery are called transsexuals. In Indonesia, after performing a sex change operation, you can apply to the District Court to get a change of identity on your residence card. When they have officially changed their gender and identity, the question that will be asked is whether the rights they will get will be the same as the rest of the general public. One of the rights of each individual is to carry out marriage, which is a marriage between a man and a woman. However, in Indonesia, there are no regulations regarding marriages carried out by transsexuals. So there is a need for a study of transsexual marriage, which would be appropriate if viewed from the perspective of natural rights theory. The purpose of this study is to describe transsexual marriage from the perspective of natural rights theory. This type of research is normative legal research using a conceptual approach. Based on the analysis carried out, it can be seen that marriages performed by transsexuals are not legal according to religion and the state because they violate the boundaries and rules that have been set by the state.Keywords: Marriage; Transsexual; Natural Rights.Abstrak: Seiring dengan perkembangan masa terdapat beberapa individu yang melakukan operasi pergantian kelamin karena merasa tubuh yang dimilikinya sekarang tidak sesuai dengan kejiwaannya. Individu yang melakukan operasi pergantian kelamin disebut dengan transeksual. Di Indonesia sendiri, setelah melakukan operasi pergantian kelamin maka dapat mengajukan ke Pengadilan Negeri untuk mendapatkan perubahan identitas pada kartu kependudukannya. Ketika secara resmi telah berubah kelamin serta identitasnya, maka yang akan menjadi pertanyaan adalah terkait hak-hak yang akan didapatkannya apakah akan dipersamakan dengan masyarakat umum lainnya. Salah satu hak setiap individu adalah melaksanakan perkawinan, yang mana perkawinan tersebut antara laki-laki dengan perempuan. Namun di Indonesia tidak ada aturan terkait perkawinan yang dilakukan oleh transeksual. Sehingga perlu adanya kajian tentang perkawinan transeksual, yang mana akan tepat jika ditinjau dari perspektif teori hak kodrati. Tujuan dari penelitian ini adalah untuk mendeskripsikan perkawinan transeksual yang ditinjau dari perspektif teori hak kodrati. Jenis penelitian ini adalah penelitian hukum normatif dengan menggunakan pendekatan konseptual. Berdasarkan analisa yang dilakukan dapat diketahui bahwa perkawinan yang dilakukan oleh transeksual tidak sah menurut agama dan negara karena melanggar batasan-batasan dan aturan yang telah ditetapkan oleh negara.Kata Kunci: Perkawinan; Transeksual; Hak Kodrati.
PERCERAIAN AKIBAT DISABILITAS MENTAL PERSPEKTIF SURAH AN-NUR AYAT 61 DAN HAK ASASI MANUSIA NASUTION
Authors: Setiyoningrum Nurlaila Indah , Yasin Raden Cecep Lukman 
Published: July 2022

Abstract: Divorce is the release of marriage bonds through the Religious Courts. Divorce with mental disabilities is a divorce carried out by the plaintiff against a defendant with a mental disability. The purpose of this study is to analyze divorce due to mental disability from the human rights perspective of Adnan Buyung Nasution and to analyze divorce from mental disability perspective from Surah An-Nur verse 61. This research method is a normative research with a case approach. The results of this study are that law enforcement on the rights of mental disabilities should also be supported by the government and law enforcement. Divorce for mental disabilities should not be granted, because it is increasingly painful and difficult to recover. In Surah An-Nur verse 61 it is stated that the rights of persons with mental disabilities are the same as normal humans, so that in treating persons with disabilities they are the same in the eyes of Allah and Islam strongly rejects discrimination against anyone.Keywords: Divorce; Mental Disability; Human Rights. Abstrak: Perceraian merupakan terlepasnya ikatan pernikahan melalui peradilan Agama. Perceraian disabilitas mental merupakan perceraian yang dilakukan oleh penguggat terhadap tergugat yang penyandang disabilitas mental. Tujuan dalam penelitian ini yaitu untuk menganalisis perceraian akibat disbilitas mental perspektif hak asasi manusia Adnan Buyung Nasution dan untuk menganalisis perceraian disabilitas mental perspektif surah An-Nur ayat 61. Metode penelitian ini yaitu penelitian normatif dengan pendekatan kasus. Hasil dalam penelitian ini yaitu penegakan hukum terhadap hak-hak disabilitas mental sebaiknya didukung pula oleh pemerintah dan penegak hukum. Perceraian terhadap disabilitas mental sebaiknya tidak dikabulkan, sebab semakin menderita dan sukar untuk sembuh. Dalam surah An-Nur ayat 61 menyatakan bahwa hak penyandang disabilitas mental itu sama seperti manusia normal, sehingga dalam memperlakukan penyandang disabilitas-pun sama di mata Allah dan Islam sangat menolak diskriminasi terhadap siapapun.Kata Kunci: Perceraian; Disabilitas Mental; Hak Asasi Manusia.