bluuebunny/crossref_metadata_2025_split huggingface dataset:
Probabilistic seismic hazard assessments for Myanmar and its metropolitan areas
Authors: Yang Huan-Bin , Chang Yuan-Kai , Liu Wei , Sung Guan-Yi , Gao Jia-Cian , Thant Myo , Maung Phyo Maung , Chan Chung-Han 
Published: July 2022

Abstract
Although Myanmar is an earthquake-prone country, there hasn’t been proposed an official national seismic hazard map.Thus, this study conducted a probabilistic seismic hazard assessment for Myanmar and some of its metropolitan areas. Performing this assessment required a set of databases that incorporates both earthquake catalogs and fault parameters. We obtained seismic parameters from the International Seismological Centre, and the fault database includes faultparameters from paper reviews and the database. Based on seismic activities, we considered three categories of seismogenic sources—active fault source, shallow area source, and subduction zone source. We evaluated seismic activity of each source based on the earthquake catalogs and fault parameters. Evaluating the ground-shaking behaviors forMyanmar requires evaluation of ground-shaking attenuation; therefore, we validated existing ground motion prediction equations (GMPEs) by comparing instrumental observations and felt intensities for recent earthquakes. We then incorporated the best fitting GMPEs into our seismic hazard assessments. By incorporating the V s 30 (the average shear velocity down to 30 m depth) map from an analysis of topographic slope, we utilized site effect and assessed nationalprobabilistic seismic hazards for Myanmar. The assessment shows highest seismic hazard levels near those faults with high slip rates, including the Sagaing Fault and along the Western Coast of Myanmar. We also assessed seismic hazard for some metropolitan cities, including Bagan, Bago, Mandalay, Sagaing, Taungoo and Yangon, in the forms of hazard curves and disaggregation by implementing detailed V s 30 maps from micro-tremor surveys. The city-scale assessments showhigher hazards for sites close to an active fault or/and with a low V s 30 , demonstrating the importance of investigating siteconditions. The outcomes of this study will be beneficial to urban planning on a city scale and building code legislation on a national scale.
How to make and trap a pseudo-vesicle with a micropipette
Authors: Wandersman Elie , Tapie Pierre , Montel Lorraine , Prevost Alexis , Pontani Lea-Laetitia 
Published: July 2022

Abstract
We present a simple method to produce giant lipid pseudo-vesicles (vesicles with an oily cap on the top), trapped in an agarose gel. The method can be implemented using only a regular micropipette and relies on the formation of a water/oil/water double droplet in liquid agarose. We characterize the produced vesicle with fluorescence imaging and establish the presence and integrity of the lipid bilayer by the successful insertion of α-Hemolysin transmembrane proteins. Finally, we show that the vesicle can be easily mechanically deformed, non-intrusively, by indenting the surface of the gel.
Lipid but not glucose metabolism is associated with 18FDG-PET/CT false negative lymph nodes in head and neck cancer
Authors: Meng Xiaoyan , Sun Jingjing , Xu Feng , Liu Zhonglong , he yue 
Published: July 2022

Abstract
Background: Lymph node metastasis frequently occurs in head and neck squamous cancer (HNSCC) patients, and [18F] fluorodeoxyglucose (FDG) positron emission tomography (PET) with computed tomography (CT) (18FDG-PET/CT) examination for lymph node metastasis could result in false negativity and delays following treatment. However, the mechanism and resolution for 18FDG-PET/CT false negatives remain unclear. Methods: In our study, ninety-two patients diagnosed with HNSCC who underwent preoperative 18FDG-PET/CT and subsequent surgery in our institution between 2018 and 2021 were reviewed. Immunohistochemistry (IHC) examinations of glucose metabolism (GLUT1 and GLUT5), amino acid metabolism (GLS and SLC1A5), and lipid metabolism (CPT1A and CD36) markers were conducted on their primary lesion as well as lymph node sections.Results: We identified metabolic rewiring in lymph node metastasis and specific metabolic activity patterns of the false negative group. More significantly, we found that CD36 and GLS in primary lesions could be promising biomarkers for distinguishing false negative nodes as CD36 IHC score of primary lesions was significantly higher in false negative group than true positive group while GLS showed the opposite association.Conclusion: IHC examination of CD36 and GLS expression in primary lesions could be used in distinguishing lymph nodes false negatives in 18FDG-PET/CT.
Factors associated with personal recovery in an outpatient sample of people with Schizophrenia in Brazil
Authors: Silva Tiago Ribeiro , Rezende Mário César , Russinova Zlatka , Farkas Marianne , Gadelha Ary , Bressan Rodrigo A. 
Published: July 2022

Abstract
PurposeThis study aimed to assess the level of personal recovery and its associated factors in a Brazilian sample of people with schizophrenia. Methods This cross-sectional study comprised a non-probabilistic sample of 104 people with schizophrenia receiving outpatient care in a university psychiatric centre. Personal Recovery was measured using the short-version of the Recovery Assessment Scale (RAS), comprising 24 items. We first examined the domains of personal recovery in the study sample and their associations of with the following clinical measures were also used: the Self-Assessment of Occupational Functioning Scale (SAOF); the general psychopathology, the Positive and Negative Syndrome Scale (PANSS); the Calgary Depression Scale for Schizophrenia; the Independent Living Skills Survey (ILSS) and the Clinical Global Impression (CGI). The mean scores of RAS domains were compared using ANOVA for repeated measures and clinical measures associated with RAS total score were identified using linear multiple regression. Significance level was p<0.05. Results RAS domains with the highest levels of recovery were “Goal/success orientation” and “Reliance on others”, while the domain “Not dominated by symptoms” presented the lowest score. Higher levels of personal recovery in general were associated only with a lower level of depressive symptoms (as measured by Calgary scale) and a higher score for occupational functioning (as measured by SAOF). ConclusionThis study replicated findings from the international literature about the domains of personal recovery and its associations with important clinical constructs. It also identified specific cultural aspects such as the importance of affective and social relationships (friends, family) for life and as support for processes recovery.
Characteristics and Outcomes of Perforating Trauma with Intraorbital Foreign Body Short Title: Perforating Trauma with Intraorbital Foreign Body
Authors: Ren Hui , Hu Xiaobing , Zhou Min , Huang Yongheng , Guo Diwen , Jiang Rui , Qian Jiang 
Published: July 2022

Abstract
Background Perforating trauma with intraorbital foreign body (IOrbFb) is a relatively rare occurrence, which is seldom reported. For this study, we analyzed a series of patients with perforating trauma with IOrbFb who attended our center to report its essential characteristics and general prognosis.Methods We conducted a retrospective chart review of 31 consecutive patients with perforating trauma with IOrbFb who were admitted to the Eye and ENT Hospital of Fudan University between 2014 and 2018. The Pearson’s and Spearman’s rank correlation was used to determine the relationships between final visual acuity and other clinical factors.Results Thirty patients (96.8%) were male and one (3.2%) was female. Eighteen patients (58.1%) had an ocular trauma score (OTS) of 1, eight patients (25.8%) had a score of 2, and five (16.1%) had a score of 3. At the end of follow-up, visual acuity was 20/40 or better in three patients (9.7%), between 20/50 and 20/200 in six patients (19.4%), 20/200 or worse in six patients (19.4%), and 16 patients (51.6%) had no light perception. Fourteen patients (45.2%) underwent evisceration or enucleation.ConclusionWe find that the visual prognosis of perforating trauma with IOrbFb is closely related to OTS and that removal of IOrbFb with current orbital surgery techniques is safe.
Original study on mathematical models for analysis of cellulose water content from absorbance/wavenumber shifts in ATR FT-IR spectrum
Authors: Cichosz Stefan , Masek Anna , Dems-Rudnicka Katarzyna 
Published: July 2022

Abstract
The aim of this research was to evaluate the applicability of the attenuated total reflectance Fourier-transform infrared (ATR FT-IR) spectroscopy in the quantitative analysis of the moisture content in cellulose (from 0.5-11.0wt.%). Innovatively, this work describes for the first time the variations in both absorbance and wavenumber of 16 absorption bands plotted as a function of cellulose water amount measured with Karl-Fischer titration. Different regression models were investigated (simple linear, semilogarithmic, power) and the adjusted coefficient of determination (R2) was given for each calculation. While model exhibited R2>90%, the standard error of calibration (SEC) was presented and an external validation has been performed. Regarding the absorbance-water content relationship, data recorded for sixteen peaks was successfully fitted with linear functions exhibiting R2>90%. The highest value of R2=98.7% and standard error of prediction SEP=6.0% have been assigned to the maximum from 3339-3327 cm-1 (-OH), proving ATR FT-IR usefulness in quantitative analysis.
A mendelian randomization study on causal effects of 25(OH) vitamin D levels on diabetic nephropathy
Authors: He Mingjie , Yang Ting , Zhou Ping , Bu Peiyan , Yang Xionghui , Zou Yan , Zhong Aimin 
Published: July 2022

Abstract
Background: Vitamin D supplementation is correlated with a reduced risk of DN, but it is unclear whether this relationship is causal.Methods: We analyzed the causal effect of vitamin D on diabetic nephropathy by using a two-sample Mendelian randomization analysis, which was based on a study comprising 4315 TypeⅠDiabetes Nephropathy (T1DN) patients, and a study with 7938 TypeⅡDiabetes Nephropathy (T2DN) patients. Meanwhile, we also repeated some previous studies on the influence of KMI and BMI on DN, as well as the effect of vitamin D on renal function.Results: MR shows that 25(OH)D has a non-causally association with the early/later stage of T1DN (early: OR =0.279, p=0.336; later: OR= 1.517, p=0.699) and T2DN (early: OR=0.915, p=0.374; later: OR= 1.209, p=0.123), nor with the kidney function of DM patients eGFRcyea (Beta=-0.038, p=0.803) or UACR (Beta=-0.353, p=0.678). ﻿Conclusions: Vitamin D may not be associated with DN or kidney function in diabetic patients.
Double trouble of Covid-19 and extreme droughts: stakeholders' dilemma between climate change adaptation and recreation services in the city and community-owned forests
Authors: Saha Somidh , Beckmann-Wübbelt Angela , Türk Lynn , Almeida Iulia , Fricke Annika , Sotirov Metodi 
Published: July 2022

Abstract
Increasing urbanization, climate change, and plant disease pose accumulative threats to city and community-owned forests (CCF). This requires the forest to adapt to new climatic conditions to continuously provide essential recreational functions for the urban population in the future. The COVID-19 pandemic increased the demand for CCF as a place to meet, play sports, and relax. However, our knowledge of challenges in combining climate change adaptation and the increased number of visits and demand for recreation in CCF management is yet limited. In this study, we, for the first time, interviewed 16 stakeholders from different backgrounds about their opinions on climate change adaptation (CCA) of CCF, its importance as a recreational space, and conflicts between the two fields of action that occurred during the COVID-19 pandemic. It is expected that comparing perspectives from different stakeholder groups can lead to improved reflection and strengthen the sustainable management of the CCF through knowledge-based and participative decision-making. Using semi-structured interviews and qualitative data analytics with MAXQDA software, we found that stakeholders particularly highlighted the importance of the recreational function of the CCF during the pandemic. At the same time, the behavior of visitors was criticized. We identified that functional conflicts between the need for relaxation and essential functions for CCA of the CCF have increased during the pandemic. These include other biodiversity and protective functions. The interviewees, therefore, suggested enhancing the local population's communication and education. Further, the possibility of increased visitor guidance has been discussed. It has been identified that more research and location-adjusted planning are needed to evaluate the use of non-native species for the urban forest’s climate change adaptation.
Standardizing Prognostication and Management of Spontaneous Basal Ganglia Hemorrhage: A Novel Scoring System
Authors: Varshney Rahul , Arora Nitish , Khullar Varun 
Published: July 2022

Abstract
Background: Factors that are used in spontaneous ICH prognostication score cannot be generalized to basal ganglia haemorrhages. Our study aimed in developing a novel scoring system for prognosticating and management of basal ganglia haemorrhages, including factors likely to influence mortality or survival. Methods: A prospective study was performed of 351 patients with spontaneous basal ganglia haemorrhage. The patients were either managed conservatively or underwent operative intervention. Mortality at 90 days was recorded. Using univariate and multivariable logistic regression, the association between various plausible factors and 90-day mortality was tested. Factors found to be significant were used to develop a novel scoring system and the association between 90-day mortality and modified ICH score was calculated. This score was subsequently used to standardize the management with a score correlation to treatment guidelines, thus advocating either conservative or operative management depending upon the score. Thus based on this scoring system, we tried to develop a range below which conservative management was advisable, a score favouring operative intervention, and a score above which operative intervention was futile, since both conservative and surgical treatment resulted in the same outcome.Results: We analyzed 339 cases, overall, 90-day mortality was 37.75% (n=128). The survival rate in patients having modified ICH score of 7 or less than 7 was 91.66%, however, it decreased to 12.19% in patients having a score > 7. A modified ICH score of 7 or less than 7 could predict the survival in 93.8% (95% CI 89.7-96.7) of patients and had a specificity of 85.9%%. The positive predictive value of modified ICH score 7 or < 7 was 91.7% (95%CI 87.1-95.0). In patients with score of 6, surgery was advisable in almost 50% of cases and the mortality was 100 percent even after surgical intervention in patients having score of 10 or more. Conclusion: Modified ICH score is a useful tool for predicting 90-days mortality, the area under the ROC curve was 93% which was higher than any other studies for spontaneous ICH. This scoring system can also aid in deciding the line of management of basal ganglia bleed patients.Trial registration: retrospectively registered
Applying Theory of Planned Behaviour to Understand Interinstitutional Collaboration in Chronic Disease Management: A Cross-Sectional Study from Fujian Province, China
Authors: Teng Li , Dai Yue , Peng Tao , Su Yuan , Pan Lingyi , Li Yueping 
Published: July 2022

Abstract
Background: The integrated management of chronic diseases in Sanming City aims to improve the efficiency and quality of chronic disease management through the collaboration between different levels of medical institutions. This study applied the theory of planned behaviour (TPB) to understand the interinstitutional collaboration in chronic disease management (ICCDM) among health care personnel.Methods: A cross-sectional study of 274 health care personnel was conducted in medical institutions in Fujian Province, China, from March 2022 to April 2022. A self-administered questionnaire based on TPB theory was applied to measure the participants' ICCDM behaviours.Results: The proposed TPB model revealed that attitude was significantly and positively associated with behaviour intention, and behaviour intention and perceived behavioural control were significant predictors of ICCDM behaviour.Conclusion: TPB provides insights into ICCDM behaviour. Due to the fact that attitude, perceived behavioural control, and behavioural intention towards ICCDM behaviour were demonstrated to be significant predictors of ICCDM behaviour, these factors may be a promising focus of ICCDM interventions in the integrated management of chronic diseases in China.
Endoscopic Ultrasound-guided Radiofrequency Ablation for Pancreatic Adenocarcinoma
Authors: Wray Curtis J. , BSA Baylee O’Brien , Cen Putao , Rowe Julie H , Faraoni Erika Y. , Bailey Jennifer , Thosani Nirav 
Published: July 2022

Abstract

INTRODUCTIONEmerging data suggests neoadjuvant chemotherapy for resectable pancreatic ductal adenocarcinoma (PDAC) is associated with improved survival. However, less than 40% demonstrate a meaningful radiographic response to NAC. Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) has emerged as a new modality to treat PDAC. We hypothesize that NAC plus EUS-RFA can be used in the management of resectable PDAC.METHODSProspective review of PDAC patients meeting criteria of resectable tumor anatomy that underwent NAC chemotherapy plus EUS-RFA followed by pancreatic resection. Radiographic imaging, perioperative and short-term outcomes were recorded. Surgical pathology specimens were analyzed for treatment response.RESULTSThree eligible patients with resectable PDAC received 4 months of neoadjuvant chemotherapy plus EUS-RFA. One month after completion of neoadjuvant treatment, all 3 patients underwent standard pancreaticoduodenectomy without complications. After a 6 week recovery, all patients completed 2 months of post-op adjuvant chemotherapy.CONCLUSIONSIn our institutional experience, this treatment protocol appears safe. Patients tolerated the combination of chemotherapy and endoscopic radiofrequency ablation. Patients underwent pancreatic resection with uneventful recovery. This novel neoadjuvant approach may provide a more effective alternative to chemotherapy alone.
Porcine testing of a novel second generation mechanical thrombectomy device to evaluate effects on arterial and venous intima and vessel integrity
Authors: Horowitz Michael , Repko Brandon , Le Hieu , Bulova Julia , Bobo Benjamin 
Published: July 2022

Abstract
Background: This investigational study reports initial results from testing a new type of mechanical thrombectomy device in a porcine model. The novel technical innovation involves the use of two manually expandable wire spheres that are capable of opening between 3-16 mm in diameter independently of one another and moving independently of one another fore and aft along a common shaft over a 5 cm distance. Methods: The investigational thrombectomy device was introduced and deployed in vivo within the porcine venous and arterial vasculature. Following deployment and device activation within the animal’s vascular system, arteries and veins were surgically explanted and histopathologic examination was conducted to determine the device’s effects on the vascular surfaces. Statistical analysis was not utilized. Results: Repeated device deployment and use in porcine veins and arteries failed to demonstrate intimal injury (radiographically and histologically) even when the device’s spheres were expanded beyond 100% of the native vessel’s diameter and translated along the vessel’s intima. Conclusions: This in vivo study of a novel mechanical thrombectomy device has demonstrated no untoward effects on the internal anatomy of instrumented arteries and veins despite active device expansion repeated surface wall fore and aft friction. Future investigations aim to demonstrate that this device can better treat acute, subacute and chronic venous and arterial thromboembolic disease as compared to currently available technologies.Trial Registration: This article does not report the results of a health care intervention on human participants.
WITHDRAWN: Effects of flow velocity and wall properties on the hydrogen production performance of microchannel reactors
Authors: Chen Junjie 
Published: July 2022

Abstract
The steam reforming of hydrocarbon or alcohol fuels has attracted increasing interest in the context of the production of hydrogen However, the mechanisms for the effects of design factors on heat transfer characteristics are still not fully understood. This study relates to a thermochemical process for producing hydrogen by the catalytic endothermic reaction of methanol with steam in a thermally integrated microchannel reforming reactor. Computational fluid dynamics simulations are conducted to better understand the consumption, generation, and exchange of thermal energy between endothermic and exothermic processes in the reactor. The effects of flow velocity and wall properties on heat transfer characteristics and reactor performance are investigated. The results indicate that the thermal conductivity of the channel walls is fundamentally important. Materials with high thermal conductivity are preferred for the channel walls. Thermally conductive ceramics and metals are well-suited. Wall materials with poor heat conduction properties degrade the reactor performance. The channel walls of the reactor must be formed using materials with excellent heat conduction properties. To avoid heat loss and increase thermal efficiency, the reactor walls are preferably as thin as possible. The combustion chamber and reforming chamber are preferably oriented so that heat is transferred from the combustion chamber into the reforming chamber. The inclusion of a pleated arrangement of reforming panels provides a more compact reforming system while retaining the desired low pressure drop characteristic of standard panel reformer configuration. The internal pressure within the containment vessel may be used to provide pressure against the exterior surface of the stack, and thereby provide structural support for the stack. The exothermic catalytic combustion reaction provides the necessary heat flux to increase the temperature of the reactants in both channels such that the endothermic reaction will occur. Design recommendations are made to improve hydrogen production performance for the reactor.
Infective Endocarditis with Escherichia coli Secondary to Urosepsis
Authors: Karunathilake Parackrama , Kularatne WKS , Bowaththage Sunil , Kobbegala KGVJ , Fasrina MZF , Nasim Fathima Nujha , Costa MN , Jezeema ZKM , Rajapaksha RMID , Ranawaka RAND 
Published: July 2022

Abstract
Infective endocarditis (IE) is a multisystem disease that results from infection, usually bacterial, of the endocardial surface of the heart. The main causative organisms of IE are gram-positive streptococci, staphylococci, and enterococci infection. Although Escherichia coli is among the most common causes of gram-negative bacteremia, IE due to this pathogen is rare. Here we report a case a 68-year-old female was presented with 10 days history of fever diagnosed with infective endocarditis according to Modified Duke Criteria where her blood culture isolated Escherichia coli organisms. On day two of admission, the patient developed an episode of atrial fibrillation, which was resolved with two stat doses of verapamil 2.5 mg. The patient was treated with intravenous cefotaxime 2 g 8 hourly. Intravenous antibiotics were continued for six weeks, and the patient had complete recovery without any complications.