bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predilections of Allied Healthcare Professionals toward an Ideal Interprofessional Education Program via Conjoint Analysis
Authors: Diño Michael Joseph S. , Caagbay Raymond C. , Orbe Joyosthie B. , Sibayan Maria Julita S. J. 
Published: May 2022

To shape competent healthcare professionals, a working educational system that facilitates multiprofessional and interprofessional partnership should be in place to foster and deliver better outcomes efficiently, enhancing the quality of healthcare education. Interprofessional Education (IPE) is learning and teaching approach where two or more healthcare professions learn with, from, and about each other. To meet the objective, academic reform that encompasses silos and profession centrism has to be instituted. This study delved into the proclivity of medical and paramedical professionals towards a curricular program that concretizes and strengthens interprofessional collaboration in practice via Conjoint Analysis. Orthogonal Array was employed to elucidate validity and applicability of the five attributes namely Content, Participants, Setting, Teaching Methods, and Format. One hundred allied healthcare professionals representing 25 countries from three international universities participated in the study. Results revealed that setting was the major factor considered when choosing an IPE program with a relative importance of 43.7%. It was followed by content with a relative importance of 15.8%. Trailing behind were teaching methods (14.5%) and participants (13.1%), respectively. The stakeholders’ perspectives will serve as a benchmark for a program to be implemented on the Philippine context in line with the ASEAN integration which is currently being embraced.
Utilization of Jackfruit (Artocarpus heterophyllus) Seed as a Bread Spread
Authors: Supit Ellen Grace , Caparida Merry Chris H. , Retutar Warlito G. , Balagtas Maribel , Taclan Lorcelie , Laborde Gladys , Oasan Ruchel , Estrada Miriam R. 
Published: May 2022

Jackfruit is the largest tree-borne fruit in the world. It is a widely cultivated and well-consumed fruit in the Philippines and other parts of South-east Asia. The seed makes up 15-18% of the fruit weight. However, the seeds are underutilized due to the lack of information about its nutritional and food product potential. Hence, the purpose of this research was to utilize the jackfruit seed as a bread spread that is nutritious, affordable, and acceptable in terms of consistency, texture, aroma and taste. The standardized recipe for the jackfruit seed spread was obtained after three trial formulations. The jackfruit seeds were cleaned and boiled for 30 minutes, then mixed with jackfruit rags, raw sugar, olive oil, lemon juice, lemon rind, turmeric powder, and salt in a blender until a paste-like consistency and smooth texture was achieved. The blended ingredients were cooked in low heat for 15 minutes to remove excess moisture, increase shelf-life, and attain a spreadable consistency. The final product was placed in sterile airtight jars. The jackfruit seed spread has the following characteristics: canary yellow color, smooth texture, lemony aroma, and sweet acidulous taste. One serving (21g) provides 82 kcal and is a source of potassium (59mg), phosphorus (8mg), calcium (26mg), magnesium (4mg), thiamin (0.02mg), riboflavin (0.02mg), niacin (0.2mg), and vitamin C (2mg). The product was rated as like very much by 30 evaluators from both genders using a nine-point hedonic scale. The jackfruit seed spread is affordable with a selling price of ₱58.00 for a jar of 200g net weight. The shelf-life is 30 days in refrigerator temperature. It was recommended that further studies be done on producing jackfruit seed spread for a large scale business in regions were jackfruit is widely cultivated.
Sí­ndrome de Stevens-Johnson: intervenções de enfermagem no tratamento tópico curativo em pediatria
Authors: Colodetti Rafael , Silva Katia Cristina Vieira 
Published: May 2022

A Sí­ndrome de Stevens-Johnson caracteriza-se por acometimento mucocutâneo múltiplo e elevada morbimortalidade. Ocorre extensa necrose de destacamento da epiderme e a área desnuda é suscetí­vel í s infecções, entretanto, nenhum consenso existe sobre os cuidados locais. Tratou-se de um Estudo de Caso acompanhado em um hospital estadual, localizado no municí­pio de Vila Velha, ES, com uma criança de sete anos, apresentando diagnóstico de varicela e de evolução concomitante com a Sí­ndrome de Stevens-Johnson. Objetivo: descrever novas intervenções de enfermagem no tratamento conservador da Sí­ndrome de Stevens-Johnson, utilizando-se de curativos especiais. A reepitelização transcorreu em vinte e dois dias de tratamento. Foi possí­vel acompanhar a cicatrização e relatar a experiência do uso dessas tecnologias em tal doença, proporcionando novas e eficazes ações de enfermagem.
A atuação multiprofissional na prevenção de lesões de pele
Authors: Gimenes Juliana Rissoli , Appolinário Juliana Correa , Souza Roberta De Oliveira 
Published: May 2022

Objetivo: Objetivou-se prevenir, identificar e estratificar possí­veis lesões de pele traçando o perfil de risco dos pacientes e suas necessidades, assim como os fatores que influenciaram no surgimento de lesões, e que podem ter ligação com as condições clí­nicas do paciente ou com os cuidados de enfermagem diretamente. Resultado: As boas práticas implantadas favoreceram a gestão de melhores resultados, com evidência na efetividade e adesão as prática de prevenção, diminuição de custos, além do reconhecimento e motivação dos nossos profissionais atuantes. No segundo semestre de 2016, tivemos 58 eventos de lesão de pele notificados (média de 10 eventos/mês); em 2017, tivemos 66 eventos de lesão de pele notificados (média de 06 eventos/mês); e no ano de 2018, tivemos 20 eventos de lesão de pele notificados (média de 02 eventos/mês), resultado comparado de 2016 a 2018, obtivemos a queda de mais de 80% no número de eventos. Desde de 2017, esta instituição passa pelo processo de certificação, e em abril de 2019 foi recertificada por desenvolver melhores práticas relacionadas í prevenção de lesão recebendo a categoria Diamante. Conclusão: Nossa experiência possibilitou diminuir 80% dos eventos de lesão de pele, o que evidencia a importância da equipe multiprofissional na avaliação, planejamento, prevenção das lesões de pele. Percebemos também, que o envolvimento do paciente e familiares nas medidas educativas e na elaboração do plano de cuidados foi de grande relevância para a continuidade de boas práticas após alta do paciente.
Interpretation of pharmacokinetic data in preclinical studies of new drugs. Single intravenous administration
Authors: Geodakyan S. V. 
Published: May 2022

Review. Further development of the methodological level of the decision support system proposed for the organization of primary selection and experimental preclinical study of new drugs. Methods for describing and interpreting the main pharmacokinetic experiment (single intravenous administration of drugs) data are systematized. A scheme for choosing pharmacokinetic models based on visual pattern recognition is proposed. Visual data patterns allow prediction of pharmacokinetic behavior and properties of new drugs.
The effect of facial occlusion on facial impressions of trustworthiness and dominance
Authors: Oliveira Manuel , Garcia-Marques Teresa 
Published: May 2022

AbstractRecognizing the role that facial appearance plays in guiding social interactions, here we investigated how occlusions of the bottom-face region affect facial impressions of trustworthiness and dominance. Previous studies suggesting that different facial features impact inferences on these traits sustain the hypothesis that wearing a face mask will differently affect each trait inference. And specifically, that trustworthiness impressions will be more disrupted by this type of face occlusion than dominance impressions. In two studies, we addressed this possibility by occluding the bottom face region of faces that were previously shown to convey different levels of dominance and trustworthiness, and tested differences in the ability to discriminate between these trait levels across occlusion conditions. In Study 1 faces were occluded by a mask, and in Study 2 by a square image. In both studies, results showed that although facial occlusions generally reduced participants’ confidence on their trait judgments, the ability to discriminate facial trustworthiness was more strongly affected than the ability to discriminate facial dominance. Practical and theoretical implications of these findings are discussed.
WELL-BEING AND PANDEMIC LOCKDOWN: THE ROLE OF EMOTIONAL INTELLIGENCE, SELF-COMPASSION AND RUMINATION
Authors: Martskvishvili Khatuna , Lagidze Nato 
Published: May 2022

The COVID-19 pandemic and its accompanying restrictions, apart from the destructive global economic and social impact, brought negative psychological consequences to the world. The aim of the current study is to investigate the factors that help individuals maintain psychological well-being under the condition of self-isolation, a global restriction against the spread of the pandemic. Specifically, the role of trait emotional intelligence, self-compassion, and rumination was explored in order to determine how these variables relate to psychological well-being. According to the results, trait emotional intelligence and self-compassion positively correlate with psychological well-being, while rumination is negatively correlated. Self-compassion mediates the relationship between emotional intelligence and well-being. The relationship between rumination and well-being is affected by emotional intelligence and self-compassion: Self-compassion mediates the relationship between depression related rumination and well-being, while self-control and emotionality factors of trait emotional intelligence moderate the relationship between reflection rumination and well-being. The findings of the current study provide insight about self-compassion, rumination, and emotional intelligence as different contributing factors to the individuals’ well-being in self-isolation, suggesting further implications about the use of these strategies to help people cope with this stressful situation.
Оценка корреляции времени экспозиции триггера финального созревания ооцитов и эмбриологических показателей (LOTTA)
Authors: Шурыгина О.В. , Юхимец С.Н. , Тугушев М.Т. , Шипулин Н.А. 
Published: May 2022

Актуальность: Современная практика вспомогательных репродуктивных технологий (ВРТ) базируется на персонифицированном подходе в рамках утвержденных клинических рекомендаций, что позволяет оптимизировать эффективность и безопасность процедур. В качестве ключевой инъекции цикла стимуляции используют триггер финального созревания ооцитов, время воздействия которого до сих пор остается спорным клиническим вопросом.
Цель: оценка корреляции времени экспозиции триггера финального созревания ооцитов и эмбриологических показателей (LOTTA).
Материалы и методы: Ретроспективное когортное одноцентровое исследование с участием 959 пациентов в возрасте от 18 до 40 лет (ЭКО/ИКСИ), у которых в качестве триггера финального созревания ооцитов применяли препарат р-ХГЧ.
Результаты: В среднем по выборке доля зрелых ооцитов MII составила 79%, частота дорастания до бластоцисты – 53%, что соответствует требованиям Венского консенсуса (2017). Ни в одном временном интервале анализируемые эмбриологические показатели не были ниже пороговых уровней, указанных в Венском консенсусе (2017). В целом по выборке была выявлена тенденция к получению большего количества зрелых ооцитов во временных интервалах 36 часов и более в сравнении с экспозицией 35 часов. По показателю частоты дорастания до бластоцисты в целом по выборке была выявлена клинически значимая разница с максимальными показателями в группе 36 часов.
Заключение: В нашем исследовании интервал экспозиции р-ХГЧ в 36 часов продемонстрировал наиболее высокие эмбриологические показатели доли зрелых ооцитов и частоты дорастания до бластоцисты. Мы считаем целесообразным продолжить данную работу путем увеличения объема выборки с фокусом на группы с 35 и 37 часами экспозиции для подтверждения выявленных тенденций.
Эмбрионы носителей робертсоновской транслокации: закономерности наследования и межхромосомный эффект
Authors: Гусейнова К.А. 
Published: May 2022

Актуальность: У носителей робертсоновских транслокаций хромосом существует риск самопроизвольных выкидышей и рождения детей с хромосомными патологиями из-за несбалансированного набора хромосом в их гаметах. Сравнительная геномная гибридизация (a-CGH) позволяет проводить комплексный скрининг на все хромосомы, что очень важно, учитывая частоту выявления у эмбрионов патологий, не связанных со структурными хромосомными перестройками родителей (так называемый межхромосомный эффект).
Цель исследования – определение закономерностей наследования и межхромосомного эффекта у эмбрионов носителей робертсоновской транслокации.
Материалы и методы: Было обследовано 20 супружеских пар. В 20 циклах было пробиопсировано 82 бластоцисты, исследовано 54 бластоцисты. Скрининг на хромосомы проводили методом a-CGH с помощью системы сканирования микроматриц Agilent G5761A (Agilent).
Результаты: По результатам анализа а-CGH, 59% бластоцист дали аномальный результат, из них только 31% несли несбалансированную перестройку, связанную с родительской транслокацией. В результате проведенного преимплантационного тестирования из 20 исследованных супружеских пар две пациентки были сняты с программы по причине отсутствия эуплоидных эмбрионов. У 11 пациенток была зафиксирована клиническая беременность (79%), в одном случае беременность замерла, все 11 женщин благополучно родоразрешились. Частота имплантации и живорождения в этих циклах составила 81%.
Заключение: С целью сохранения здоровья женщины и сокращения времени до наступления беременности здоровым ребенком, супружеским парам с транслокациями предлагается проведение программы ВРТ с ПГТ-А методом a-CGH.
Наступление беременности после ЭКО у cупруги пациента с немозаичной формой синдрома клайнфельтера: клинический случай
Authors: Онлас А.Р. , Безруков Р.В. , Карибаева Г.М. , Джусубалиев Н.М. , Гусейнова К.А. , Шишиморова М.С. 
Published: May 2022

Актуальность: Синдром Клайнфельтера – врожденное генетическое заболевание лиц мужского пола, обусловленное наличием в мужском кариотипе дополнительной одной или более Х-хромосомы и отсутствием сперматозоидов в эякуляте (азооспермия). С появлением вспомогательных репродуктивных технологий (ВРТ) и внедрением в урологии микрохирургических операций, таких как микродиссекция семенников и извлечение сперматозоидов (microdissection testicular sperm extraction, micro-TESE), достижение беременности и рождение ребенка стало доступно для данной категории пациентов. По данным литературы, процент рождения здоровых детей у таких пациентов составляет 28% по миру, а общее их число уже более 150. В Казахстане подобные случаи ранее не были описаны в литературе.
Цель: представить клинический случай наступления беременности у супруги пациента с немозаичной формой cиндрома Клайнфельтера.
Методы: В статье описан клинический случай достижения беременности методом экстракорпорального оплодотворения, интрацитоплазматической инъекции сперматозоида ЭКО/ИКСИ с проведением преимплантационного генетического тестирования анеуплоидии (ПГТ-А) методом сравнительной геномной гибридизации (array-CGH) у супруги пациента с немозаичной формой cиндрома Клайнфельтера.
Результаты: На момент публикации статьи у супруги пациента с немозаичной формой cиндрома Клайнфельтера беременность маточная, одноплодная, прогрессирует и составляет 30-31 акушерских недель.
Выводы: Становление и развитие ВРТ, внедрение micro-TESE в урологии даёт возможность пациентам с генетическим заболеванием синдром Клайнфельтера стать биологическими отцами. Комплексный подход, включающий в себя современную микрохирургию, усовершенствованную технологию ВРТ и преимплантационное генетическое тестирование, наряду с благоприятным репродуктивным возрастом пациентов продемонстрировали успешный исхода наступления беременности в программе у пары с таким тяжелым мужским фактором бесплодия, как cиндром Клайнфельтера. Для дальнейшего изучения данной темы необходимо продолжение наблюдения за развитием беременности и последующим рождением здорового ребенка у супруги пациента с немозаичной формой cиндрома Клайнфельтера.
Integral Field Spectroscopy with the Solar Gravitational Lens
Authors: Madurowicz Alexander , Macintosh Bruce 
Published: May 2022

Abstract
The prospect of combining integral field spectroscopy with the solar gravitational lens (SGL) to spectrally and spatially resolve the surfaces and atmospheres of extrasolar planets is investigated. The properties of hyperbolic orbits visiting the focal region of the SGL are calculated analytically, demonstrating trade-offs between departure velocity and time of arrival, as well as gravity assist maneuvers and heliocentric angular velocity. Numerical integration of the solar barycentric motion demonstrates that navigational acceleration of

dv
≲
80

m

s

+
6.7

m

s

t

year

is needed to obtain and maintain alignment. Obtaining target ephemerides of sufficient precision is an open problem. The optical properties of an oblate gravitational lens are reviewed, including calculations of the magnification and the point-spread function that forms inside a telescope. Image formation for extended, incoherent sources is discussed when the projected image is smaller than, approximately equal to, and larger than the critical caustic. Sources of contamination that limit observational signal-to-noise ratio (S/N) are considered in detail, including the Sun, the solar corona, the host star, and potential background objects. A noise mitigation strategy of spectrally and spatially separating the light using integral field spectroscopy is emphasized. A pseudo-inverse-based image reconstruction scheme demonstrates that direct reconstruction of an Earth-like source from single measurements of the Einstein ring is possible when the critical caustic and observed S/N are sufficiently large. In this arrangement, a mission would not require multiple telescopes or navigational symmetry breaking, enabling continuous monitoring of the atmospheric composition and dynamics on other planets.
A Monte Carlo Method for Evaluating Empirical Gyrochronology Models and Its Application to Wide Binary Benchmarks
Authors: Otani Tomomi , von Hippel Ted , Buzasi Derek , Oswalt T. D. , Stone-Martinez Alexander , Majewski Patrice 
Published: May 2022

Abstract
Accurate stellar ages are essential for our understanding of the star formation history of the Milky Way and Galactic chemical evolution, as well as to constrain exoplanet formation models. Gyrochronology, a relationship between stellar rotation and age, appears to offer a reliable age indicator for main-sequence (MS) stars over the mass range of approximately 0.6–1.3 M
⊙. Those stars lose their angular momentum due to magnetic braking and as a result their rotation speeds decrease with age. Although current gyrochronology relations have been fairly well tested for young MS stars with masses greater than 1 M
⊙, primarily in young open clusters, insufficient tests exist for older and lower mass MS stars. Binary stars offer the potential to expand and fill in the range of ages and metallicity over which gyrochronology can be empirically tested. In this paper, we demonstrate a Monte Carlo approach to evaluate gyrochronology models using binary stars. As examples, we used five previously published wide binary pairs. We also demonstrate a Monte Carlo approach to assess the precision and accuracy of ages derived from each gyrochronology model. For the traditional Skumanich models, the age uncertainties are σ
age/age = 15%–20% for stars with B − V = 0.65 and σ
age/age = 5%–10% for stars with B − V = 1.5 and rotation period P ≤ 20 days.
Analytical Modeling of Exoplanet Transit Spectroscopy with Dimensional Analysis and Symbolic Regression
Authors: Matchev Konstantin T. , Matcheva Katia , Roman Alexander 
Published: May 2022

Abstract
The physical characteristics and atmospheric chemical composition of newly discovered exoplanets are often inferred from their transit spectra, which are obtained from complex numerical models of radiative transfer. Alternatively, simple analytical expressions provide insightful physical intuition into the relevant atmospheric processes. The deep-learning revolution has opened the door for deriving such analytical results directly with a computer algorithm fitting to the data. As a proof of concept, we successfully demonstrate the use of symbolic regression on synthetic data for the transit radii of generic hot-Jupiter exoplanets to derive a corresponding analytical formula. As a preprocessing step, we use dimensional analysis to identify the relevant dimensionless combinations of variables and reduce the number of independent inputs, which improves the performance of the symbolic regression. The dimensional analysis also allowed us to mathematically derive and properly parameterize the most general family of degeneracies among the input atmospheric parameters that affect the characterization of an exoplanet atmosphere through transit spectroscopy.
A Babcock–Leighton-type Solar Dynamo Operating in the Bulk of the Convection Zone
Authors: Zhang Zebin , Jiang Jie 
Published: May 2022

Abstract
The toroidal magnetic field is assumed to be generated in the tachocline in most Babcock–Leighton (BL)-type solar dynamo models, in which the poloidal field is produced by the emergence and subsequent dispersal of sunspot groups. However, magnetic activity of fully convective stars and MHD simulations of global stellar convection have recently raised serious doubts regarding the importance of the tachocline in the generation of the toroidal field. In this study, we aim to develop a new BL-type dynamo model, in which the dynamo operates mainly within the bulk of the convection zone. Our 2D model includes the effect of solar-like differential rotation, one-cell meridional flow, near-surface radial pumping, strong turbulent diffusion, BL-type poloidal source, and nonlinear back-reaction of the magnetic field on its source with a vertical outer boundary condition. The model leads to a simple dipolar configuration of the poloidal field that has the dominant latitudinal component, which is wound up by the latitudinal shear within the bulk of the convection zone to generate the toroidal flux. As a result, the tachocline plays a negligible role in the model. The model reproduces the basic properties of the solar cycle, including (a) approximately 11 yr cycle period and 18 yr extended cycle period; (b) equatorward propagation of the antisymmetric toroidal field starting from high latitudes; and (c) polar field evolution that is consistent with observations. Our model opens the possibility for a paradigm shift in understanding the solar cycle to transition from the classical flux transport dynamo.
Stable Mass Transfer Can Explain Massive Binary Black Hole Mergers with a High-spin Component
Authors: Shao Yong , Li Xiang-Dong 
Published: May 2022

Abstract
Recent gravitational-wave observations showed that binary black hole (BBH) mergers with massive components are more likely to have high effective spins. In the model of isolated binary evolution, BH spins mainly originate from the angular momenta of the collapsing cores before BH formation. Both observations and theories indicate that BHs tend to possess relatively low spins; the origin of fast-spinning BHs remains a puzzle. We investigate an alternative process that stable Case A mass transfer may significantly increase BH spins during the evolution of massive BH binaries. We present detailed binary evolution calculations and find that this process can explain the observed high spins of some massive BBH mergers under the assumption of mildly super-Eddington accretion.