bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical features of depression in women and men with bipolar affective disorder
Authors: Stolyarova A. , Tyuvina N. , Balabanova V. 
Published: September 2022

Introduction

Knowledge of the main markers of bipolarity, clinical features and the course of depression within BPAD in men and women will contribute to the correct diagnosis, prog- nostic assessment of the disease course and administration of an adequate therapy.ObjectivesThe aim of the investigation was to study the clinical features of depression in men and women with BPAD in order to identify markers of bipolarity, facilitate a diagnostic search and determine therapeutic tactics.MethodsThe study was conducted from 2018 to 2020 in outpatient and inpatient conditions of the S. S. Korsakov Psychiatric Clinic of Sechenov University. 100 patients (50 women and 50 men) with a diagnosis of F31.3-F31.5 according to ICD-10 were examined by the clinical method.ResultsIn the structure of the depressive phase in men, the following were more common: pronounced seasonality (with deterioration in autumn-winter) and daily fluctuations in the state (with improvement in the evening), anesthesia of the senses, depersonalization-derealization syndrome, decreased libido, difficulty falling asleep and increased appetite and / or body weight, comorbid depression, panic attacks and alcohol and surfactant abuse. Depression within the BPAD in women was characterized by a more frequent presence of apathy, tearfulness, self-harm, dysmorphophobic inclusions, decreased appetite.ConclusionsThe revealed features of psychopathological symptoms and correlations between some characteristics and factors, taking into account gender differences, can be used as markers of bipolarity, which will allow for an earlier and more accurate diagnosis of BPAD and adequate therapy.DisclosureNo significant relationships.
Developing an online positive psychology application for people with bipolar disorder; ‘How expectations of consumers and professionals turned into an intervention.’
Authors: Geerling B. , Kelders S. , Stevens A. , Kupka R. , Bohlmeijer E. 
Published: September 2022

IntroductionIn Bipolar Disorder (BD), people report a lower quality of life and lower levels of well-being than the general population. Additionally, patients with bipolar disorder have unmet needs which are closely linked to elements of positive psychology.ObjectivesThe current study aimed to gain insight from patients with BD and care professionals about their thoughts of online Positive Psychology Interventions (PPI) to develop an app containing PPI’s for people with BD.MethodsThe study is conducted in accordance with the CeHRes roadmap principles. Data were collected by focus groups, questionnaires, rapid prototyping and online feedback from the participants. Three focus groups meetings (FGM) were held with consumers (8) and professionals (5).ResultsThe FGM reveals a need for positive psychology interventions to cover some of the unmet needs that can be applied in an app in addition to the guidelines-advised treatment. Patients and professionals expect that PPIs in the current treatment in BD can meet some of the needs that are currently still unmet, specifically offering hope, increasing self-esteem, expressing feelings, acceptation and preventing social isolation. The process of contextual inquiry and value specification is helpful to guide this process.ConclusionsThe consensus on the different topics about the use of positive psychology intervention shows that both consumers and professionals underline the importance of applying PPI’s in BD. The use during subsyndrome and mild depressive episodes seem the most beneficial periods for patients with BD. A more extended study has to be conducted to confirm if these findings are more generalizableDisclosureNo significant relationships.
Interreg and WHO-CC : a Fruitful Collaboration in the Service of E-Mental Health
Authors: Sebbane D. 
Published: September 2022

Within the IT4Anxiety project, the World Health Organisation Collaborating Centre (WHOCC) for research and training in mental health of Lille, is the leader of the work package “identification of needs among the different actors in the mental health field”. The complexity of our object of study - the use of new technologies for people’s mental health - requires undertaking a multi-disciplinary approach, considering both the clinical and the socio-anthropological aspects. A mixed-methods research conducted with pepole people experiencing anxiety, carers and professionnals, aims to describe the use, acceptability and needs of the different categories of actors concerned by the use of new technologies. The quantitative part is a cross-sectional, descriptive, observational study. A anonymous self-administered questionnaire is distributed online and in hard copy in the 5 partner countries (Belgium, France, Germany, the Netherlands and the UK) to the three study populations. It consists of access to digital tools or technological solutions, experience related to these and the contribution and perceived effect of users to e-mental health related projects. The qualitative approach includes a detailed understanding of the potential therapeutic and socio-anthropological changes that these tools can bring. It explores : description of used technologies, the representations and emerging needs in relation to the management of anxiety and the improvement of mental health ; the clinical impact perceived by all stakeholders and the implementation of new ways of living with the tools. This international research will enable a comparative study to be carried out on the dynamics of appropriation of these e-(mental) health devices in different countries of the North-Western European region.DisclosureNo significant relationships.
Mixed features in depression: frequency and associated factors
Authors: Charaa O. , Ouali U. , Zgueb Y. , Aissa A. , Jomli R. , Nacef F. 
Published: September 2022

Introduction

Mixed states in mood disorders present significant clinical and prognostic challenges. Although the DSM-5 has broadened diagnostic criteria for mixed states with the development of the ‘mixed features’ specifier and its application to unipolar depressive disorders, some mixed episodes might still be overlooked.Objectivesto evaluate the frequency and the factors associated with mixed depression according to the broader Koukopoulos criteria in a sample of patients with a major depressive episodeMethodsWe included 99 consecutive patients presenting for a major depressive episode of bipolar (n=10) or unipolar major depressive (n=89) disorder at our outpatient clinic. Major depression was ascertained using SCID- IV criteria, and mixed features were determined using Koukopoulos’ diagnostic criteriaResults
Mean age of the sample was 35.5 years [14-58]. Women accounted for 63.6% of patients. Mixed features were found in 19.5% (n=19) of the sample, 80% (n=8) among patients with bipolar disorders (BD) and 12.3% (n=11) among those with major depressive disorder (MDD). Individuals with mixed features had more substance abuse (p=0.005) and more suicide attempts (p=0.01). Individuals receiving antipsychotics had a lower risk of mixed features (p=0.000) while antidepressant treatment did not have any affect. A family history of BD, psychosis, suicide and substance abuse were found in these patients. Mixed features in depression were more frequent in patients with BD than in MDD.ConclusionsOur study showed a high frequency of mixed features in depression, especially bipolar depression when Koukopoulos criteria are applied. Special attention should be given to these patients given the association with substance use and suicidalityDisclosureNo significant relationships.
Evaluation of functioning among euthymic bipolar patients
Authors: Mhiri E. , Ben Thabet J. , Feki R. , Smaoui N. , Gassara I. , Zouari L. , Omri S. , Maalej M. , Charfi N. , Maalej M. 
Published: September 2022

IntroductionNumerous studies have documented high rates of functional impairment among bipolar disorder patients, even during phases of euthymia.ObjectivesTo study different domains of functioning impairment in bipolar patients during euthymic phase.MethodsA cross-sectional and descriptive study of 78 patients followed for bipolar disorder, during euthymia, at the psychiatric outpatient clinic at CHU Hédi Chaker in Sfax. We used a socio-demographic and clinical data sheet and the Functioning Assessment Short Test (FAST) to assess functionning : A functional impairment was retained for a total FAST score > 11.ResultsThe average age was 36.27 years, the sex ratio was 5.5. Bipolar I disorder was diagnosed in 88.5% of patients. The mean age of onset was 27.73 years, and the mean duration of illness was 8.4 years. *The mean total score at the FAST was 22.23. *Functioning was altered on 69.2% of patients. *The occupational and the cognitive functioning were the two most altered domains in our population (respective mean scores : 8.69 and 5.74). *Autonomy was altered on 17.9% of patients. *Occupationnal functioning was altered on 76.9% of patients. *Cognitive functioning was altered on 70.5% of patients. *Financial issues were observed on 34.6% of patients. *Interpersonal relationships were altered on 41% of patients. *Leisure time difficulties were present with 24.4% of patients.ConclusionsThis work has focused on the very high frequency of functional handicap in euthymic bipolar patients. Thus, several measures must be put in place to prevent or mitigate the negative effects of the impaired functioning on these patients.DisclosureNo significant relationships.
Are there clinical and sociodemographic differences between bipolar i and ii disorders?
Authors: Piazza F. , Rodríguez Rey A. , Montejo L. , Solé B. , Martínez-Arán A. 
Published: September 2022

IntroductionBipolar disorder is a serious mental disorder. Although bipolar disorder I (BDI) might seem to have a more complex evolution and severe prognosis than bipolar disorder II (BDII) because of cross-sectional symptom severity, BDII has a high episode frequency, high rates of psychiatric comorbidities and recurrent suicidal behaviours that impair functioning and quality of life.ObjectivesTo explore whether there are differences between patients with BDI and BDII concerning sociodemographic and clinical variables of interest.MethodsA sample of 407 euthymic patients with bipolar disorder (307 BDI and 100 BDII) being age 18 or older was recruited from the Bipolar and Depressive Disorders Unit of the Hospital Clinic of Barcelona. Sociodemographic and clinical variables were collected through the administration of semi-structured interview and clinical scales. Differences between groups in these variables were analysed using the Mann-Whitney U and Chi-square tests, as appropriate. The level of significance was set at p <0.05.ResultsWe found statistically significant differences between both groups. Patients with BD II were older (p<0.001), presented a longer illness duration (p=0,001) and a greater subsyndromal depressive symptomatology (p=0,010). Patients with BDI had a higher number of previous hospitalizations (p<0,001) and higher rates of psychotic symptoms (p<0,001) even during the first episode (p<0,001).ConclusionsOur data suggests that clinical differences exist between both bipolar subtypes. The episodes may be more serious, with a greater presence of a history of psychosis, and require more hospitalizations in BDI patients. In the BDII group, persistent subsyndromal symptoms may predominate, especially of the depressive pole.DisclosureNo significant relationships.
Internet-delivered psychological treatment of functional gastrointestinal disorders in youth: Study protocol for exploration of cognitive biases
Authors: Nielsen E. , Kallesøe K. , Bjerre-Nielsen E. , Gehrt T. , Bonnert M. , Frostholm L. , Rask C. 
Published: September 2022

Introduction
Functional gastrointestinal disorders (FGID) are common in children and adolescents (CA), cause functional disability and high health care use. Internet based cognitive behavioral therapy (i-CBT) have shown promising effect in Sweden. The treatment is exposure based and target avoidance behavior. Cognitive biases regarding bodily symptoms are suggested to be part of development and maintenance of functional disorders in adults, and could therefore be an important treatment target. Little is known about cognitive biases in CA with FGID, and hence the potential importance, it is crucial to explore more in depth. This study is embedded in The Danish FGID Treatment Study which aims to test Swedish i-CBT treatment in a Danish context.Objectives1) Examine cognitive biases in CA with FGID, compared with healthy controls. 2) Asses these biases before and after treatment for FGID to investigate changes and impact on treatment effect.MethodsWe developed a novel experimental approach to examine possible cognitive biases in CA. It consists of a picture task and a FGID-specific version of the Health Norms Sorting Task. We will examine 60 CA with FGID, who are included in The Danish FGID Treatment Study before and after treatment. In addition we will perform the test on 100 healthy controls.ResultsThe results are expected to improve our understanding of maintaining cognitive factors in CA with FGID, and how these may affect outcome and change during treatment, and how they differ from the general population.ConclusionsThis study can provide new targets for treatment approaches.DisclosureNo significant relationships.
Headspace, a youth integrated care model: The relation between users satisfaction, clinical and demographic characteristics and service utilization
Authors: Hoter Ishay G. , Roe D. 
Published: September 2022

IntroductionYouth integrated care services were developed to overcome common barriers to mental health treatment. Satisfaction is key for services utilization and engagement.ObjectivesTo study users satisfaction with youth integrated care service, “Headspace”, throughout the course of treatment and its correlation with clinical and demographic characteristics and service utilization.MethodsA sample of 112 participants ranging between ages 12-25 who attended the Headspace clinic between March 2016 and June 2018 were assessed in the middle (after 7 sessions) and end of treatment (n=71).Results

Participants expressed high levels of satisfaction across all service aspects at the middle and end of treatment. The highest rate of satisfaction was with the centre’s staff and the lowest with personal outcomes. A repeated measures ANOVA analysis revealed that only satisfaction with personal outcomes improved significantly over time Length of wait to begin treatment and parental engagement y were negatively correlated with youth satisfaction.ConclusionsSatisfaction rates of Headspace among youth are high from the start and with their outcomes increase over time. Youth satisfaction with the staff’s attitude and approach and satisfaction with accessibility suggest the service achievement in addressing barriers of help seeking in youth.DisclosureNo significant relationships.
Self-reported Depressive Symptoms of school-age siblings of individuals with an Autism Spectrum Disorder (ASD): Findings from a Greek sample
Authors: Koukouriki E. 
Published: September 2022

IntroductionPrevious studies have shown elevated levels of depressive symptoms in parents of children with ASD. However, few studies have assessed depressive symptoms in neurotypical ASD-siblings and most have done so, within a broad age range, while studies focusing on a certain developmental stage (middle childhood in particular) using a self-report depression-specific assessment tool are sparse.Objectives
This study aimed to investigate the depressive symptoms of Greek school-age neurotypical siblings of individuals with an Autism Spectrum Disorder through a self-reported questionnaire.Methods
The sample included 85 school-age neurotypical ASD-siblings (8-13 years old). The Children’s Depression Inventory (CDI) and a demographics questionnaire were administered to all participants.ResultsResults showed that a considerable percentage of the sample (15.3%) scored twice as high as the mean score. ASD-siblings in the present study scored higher (mean total score in CDI was 7.24±6.27) than children of similar age and nationality. Further, 5.9% of the siblings in the present study exhibited severe depressive symptoms (using 19 as a threshold) whereas 12.9% of ASD-siblings scored above 15 and therefore should be further evaluated by mental health services.ConclusionsThe results of the present study documents a relatively high prevalence of depressive symptoms in neurotypical siblings of individuals with ASD. ASD-siblings showed higher levels of depressive symptoms compared to normative data. This is the first study addressing depressive symptoms in siblings of autistic children conducted in the Greek cultural context. The present study highlights the need for the development and implementation of appropriate and effective interventions within the Greek healthcare system for ASD-siblings.DisclosureNo significant relationships.
The system of institutional care for children with developmental disabilities in Russia: problems and current results of reforming
Authors: Rusakovskaya O. , Volodenkova E. 
Published: September 2022

IntroductionAs part of the full-sized personal examination of persons, living in residential facilities for mentally disabled people (Kekelidze, 2020) 621 children, living in 3 asylums “for children with mental retardation” of Krasnoyarsk region were examined. In 134 cases diagnosis “Moderate or severe mental retardation” wasn’t confirmed. In 2020 a full examination of 47 children with non-confirmed diagnoses was carried out in one of the asylums.ObjectivesThe main purpose of this investigation is to present the results of this full examination and sum up the main problems of the system of institutional care for children with intellectual and developmental disabilities in Russia.MethodsClinical and psychological examination, Wechsler Intelligence Scale for Children (WISC-II), analysis of pedagogical characteristics.Results
Figure 1 presents the results of cluster analysis of WISC-II. In 37 cases diagnoses were reversed to Mild intellectual disability. In one case – 10 y.o. boy - to developmental delay through social-pedagogic neglect.In the beginning of 2021 32 children were transferred to boarding schools with educational programme for children with mild intellectual disabilities. 13 children adapted to new developmental and educational conditions relatively successfully, 4 children – unsuccessfully and were returned to the first institute.ConclusionsThe success of adaptation did not depend on IQ, but on the age of the child and the severity of emotional and behavioral disorders, as well as on the willingness of the institution to provide personalized assistance to the child. The results identify the main problems of the system of institutional care for children with developmental disabilities in Russia.DisclosureNo significant relationships.
Videoconference Anxiety: Conceptualization, Scale Development and Preliminary Validation
Authors: Gözpınar N. , Görmez V. 
Published: September 2022

IntroductionWith measures of COVID-19, activities that cover a large part of life have started to be carried out via videoconferencing. Videoconferencing can be disadvantageous for individuals with social anxiety due to increased social presence, decreased mutual understanding and consequently causing awkward communication.ObjectivesThis study aims to develop a scale to explore the difficulties experienced by individuals with social anxiety during videoconferencing.Methods598 children and adolescents between the ages of 11-18 participated in the study. The data were collected with Sociodemographic Information Form, Videoconference Anxiety Scale and Liebowitz Social Anxiety Scale.ResultsAccording to correlation analysis, all correlations between Videoconference Anxiety Scale and Liebowitz Social Anxiety Scale total score and subscale scores are above 0.50. According to EFA, the scale consisted of 25 items and a single factor. Factor loads were between 0.62 and 0.81, the single factor explained 52.95% of the variance. Model fit indices after CFA were as follows: X2/df:3.360, GFI:.850, IFI:.900, TLI:.890, CFI:.900, RMSEA:.078, SRMR:.0475. Convergent and discriminative validity of the scale was tested. Standardized factor loads of all items were higher than 0.50. AVE value was 0.47, while CR value was 0.96. Cronbach’s alpha coefficient of 25-item VAS is 0.96.ConclusionsThis study showed that Videoconference Anxiety is a phenomen which is higly correlated with social anxiety and Videoconference Anxiety Scale is a valid and reliable instrument for Turkish children and adolescents.DisclosureNo significant relationships.
Emotional Dysregulation and Altered Reward Processing in Self-Harm
Authors: Yavuz E. , Di Simplicio M. , Rodrigues R. 
Published: September 2022

IntroductionSelf-Harm (SH) is any act of self-injury carried out by somebody irrespective of motivation. SH most commonly functions to relieve negative affect (NA). Tentative evidence suggests reward processing is altered in SH. NA may trigger reward hypersensitivity and therefore SH. Whether NA influences reward processing in SH remains unclear.ObjectivesTo investigate whether self-harmers differ in motivation to obtain SH stimuli than healthy controls (HCs) following NA induction.HypothesisAfter NA induction, SH participants will have a significantly shorter reaction latency (RL) and greater reaction accuracy (RA) than HCs in the SH condition of the Incentive Delay (ID) task.Methods16-25-year-old SH (n=35) and HC (n=20) participants were recruited online and underwent the Trier Social Stress Test, to induce NA, followed by the ID task, where participants were cued to respond to a target as quickly as possible. On responding, an image of either a SH act (SH Condition), people socializing (Social Condition) or money (Monetary Condition) appeared. Each condition included control trials showing a neutral image. RA was the percentage of trials responded to within the target’s presentation time. RL was the time (seconds) between target appearance and participants’ response.ResultsThere was no significant main effect of group, condition or group x condition interaction for RL. There was a significant main effect of condition (p < 0.05) but not of group nor a group x condition interaction for RA.ConclusionsReward processing did not differ in the SH group compared to HCs post-NA induction. Future studies could investigate reward processing in longitudinal and larger SH samples.DisclosureNo significant relationships.