bluuebunny/crossref_metadata_2025_split huggingface dataset:
In situ Quenchreaktionen von enantiomerenangereicherten sekundären Alkyllithiumreagenzien im Kolben und im kontinuierlichen Durchfluss mittels eines I/Li‐Austausch
Authors: Kremsmair Alexander , Wilke Henrik R. , Harenberg Johannes H. , Bissinger Benjamin R. G. , Simon Matthias M. , Alandini Nurtalya , Knochel Paul 
Published: October 2022

AbstractWir berichten über ein praktisches In situ Quenchverfahren (ISQ), bei dem chirale sekundäre Alkyllithiumverbindungen aus sekundären Alkyliodiden (einschließlich funktionalisierter Iodide, die einen Ester oder ein Nitril tragen) in Gegenwart verschiedener Elektrophile wie Aldehyde, Ketone, Weinreb‐Amide, Isocyanate, Disulfide oder Boronate erzeugt werden. Diese ISQ‐Reaktion ermöglichte die Herstellung eines breiten Spektrums optisch angereicherter Ketone, Alkohole, Amide, Sulfide und Boronsäureester mit typischerweise 90–98 % ee. Bemerkenswert ist, dass diese Reaktionen bei −78 °C oder −40 °C im Kolben durchgeführt werden konnten. Ein kontinuierlicher Durchflussapparat erlaubte Reaktionstemperaturen zwischen −20 °C und 0 °C und ermöglichte eine Hochskalierung auf das 40‐fache ohne weitere Optimierung.
Structures and magnetic properties of two series of Schiff base binuclear lanthanide complexes
Authors: Lu Ying , Huang Zhong‐Ming , Zou Hua‐Hong , Liang Fu‐Pei 
Published: October 2022

Until now, although there are many examples of studying the magnetic properties of Schiff base binuclear lanthanide complexes, the relationship between the structure and magnetic properties of the complexes still is worth further investigation in order to improve the magnetic properties of Schiff base lanthanide complexes. In this work, we successfully obtained two series of binuclear Ln complexes by in situ reaction of 4‐diethylaminosalicylaldehyde, benzoic hydrazide and different lanthanide salts at 80°C under solvothermal conditions, namely, [Ln2(L)3(NO3)3]·CH3CN·CH3OH·H2O [Ln = Dy (1), Ho (2), Gd (3) L = deprotonated 4‐diethylamino salicylaldehyde benzoylhydrazine], [Ln2(L)4(CH3COO)]CH3COO·CH3CN [Ln = Dy (4), Ho (5), Gd (6)]. The complex 1 contains three Schiff base ligands L, two Dy (III) ions, and three NO3−. The ligand H1L is formed by in situ Schiff base reaction with 4‐diethylaminosalicylaldehyde and benzoic hydrazide with the participation of Ln (NO3)3. When replacing Ln (NO3)3 with Ln (OAc)3, obtained three μ2‐OAc bridged binuclear Ln (III) complexes. The magnetic study showed that complex 4 exhibits field‐induced single‐molecule magnet (SMM) behavior while complex 1 does not show any SMMs behavior. In addition, we have studied the magnetocaloric effect of complexes 3 and 6, their maximum −ΔSm values are 21.37 J kg−1 K−1 and 15.32 J kg−1 K−1, respectively, under ΔH = 7 T and T = 2 K.
Disjunctive fuzzy optimisation of electricity generation by biomass power producers in a feed‐in tariff programme
Authors: Nair Purusothmn Nair S Bhasker , Andiappan Viknesh , Foo Dominic C. Y. , Chemmangattuvalappil Nishanth G. 
Published: October 2022

AbstractThe global drive to achieve the climate change mitigation targets set during the Paris Agreement and COP26 necessitates sustainable electricity generation from renewable energy sources. However, renewable energy systems face economic challenges due to unattractive feed‐in‐tariffs (FiT). This paper presents a mathematical programming model to optimise the participation and electricity generation by biomass power plants in a FiT programme. A disjunctive fuzzy optimisation approach is adopted in this work due to the presence of several biomass power plants, thus resulting in a multi‐objective optimisation. The newly developed mixed‐integer linear programming (MILP) model maximises the overall satisfaction extent of biomass power plants in power generation. The optimisation model ensures the satisfaction of all biomass power plants' technical and economic constraints. A base case study of seven power plants utilising various palm biomass is used to demonstrate the disjunctive fuzzy optimisation approach for the MILP model. This is followed by a scenario investigating the impact of demand variation. The optimisation of the case studies favours the utilisation of empty fruit bunch (EFB), palm oil mill effluent (POME), and palm mesocarp fibre (PMF) for sustainable electricity generation. Palm kernel shell (PKS) is the least preferred palm biomass due to its lowest net availability of useful energy from biomass combustion. This work provides a decision tool for the selection of biomass type during electricity generation. The MILP model in this work may be readily extended for any number of power plants, handling a variety of biomass feedstocks.
Fabricating a new immobilization matrix based on a conjugated polymer and application as a glucose biosensor
Authors: Tan Burcu , Baycan Fatma 
Published: October 2022

AbstractA new monomer named 4‐(dihexylamino)9,12‐di(thiophen‐2‐yl)‐7H‐benzo[de]benzo[4,5]imidazo[2,1‐a]isoquinolin‐7‐one (ThBN) is synthesized and used as a potential glucose biosensor after electropolymerization of the ThBN on the graphite pencil electrode. The amount of glucose is determined according to the decrease in the amount of oxygen by using cyclic voltammetry technique. Herein, conjugated polymer of ThBN is used as a immobilization matrix. The synthesized PThBN is found to be effective enzymatic biosensor having wide linear glucose determination range between 2.975 × 10−3 and 2.087 mM with a limit of detection of 0.0304 mM and a sensitivity of 0.1326 μA/mM cm2. This potential enzymatic biosensor has been also tested in commercial samples and found to be useful to detect the glucose concentration.
Flagellate dermatitis: An atypical skin finding in adult‐onset Still's disease
Authors: Toujani Sana , El Ouni Amira , Belhassen Asma , Bouslama Kamel 
Published: October 2022

AbstractA 23‐year‐old woman followed for adult‐onset Still's disease (AOSD) presented fever and chest pain. Clinical examination showed erythematous papules suggestive of flagellate dermatitis. Laboratory findings showed increased Cardiac troponin. Myocarditis due to AOSD was therefore suspected. The patient was treated with prednisone and methotrexate with significant clinical improvement.
Anion‐Coordination‐Driven Assembly: From Discrete Supramolecular Self‐Assemblies to Functional Soft Materials
Authors: Zhang Wenyao , Zhao Jie , Yang Dong 
Published: October 2022

AbstractAnion templated assembly of supramolecular systems has been extensively explored in previous reports, whereas anions serve only as an auxiliary and spectator role. With the development of anion coordination chemistry in recent years, anion coordination‐driven assembly (ACDA) has emerged as a new strategy for the construction of supramolecular self‐assemblies. Anions are proved to exist as the main actors in the construction of supramolecular architectures, i. e., serve as the coordination center. This Review will focus on the recent progress in anion‐coordination‐driven assembly of discrete supramolecular architectures, such as helicates, polyhedrons and polygons, and the various applications of ‘aniono’‐systems. At the end of this Review, we highlight current challenges and opportunities for future research of anion‐coordination‐driven self‐assembly.
Microfilaria in cervicovaginal Pap smears: A common parasite hiding in an unusual site: Short series of four cases with literature review
Authors: Kumar Tarun , Ganesh R. Abhirami , Surabhi  , Sinha Ruchi , Bhadani Punam Prasad 
Published: October 2022

AbstractIn India, filariasis is a severe and significant public health problem. It has been reported to be present in any potential site. However, cervicovaginal Pap smear cytology rarely contains microfilariae despite the widespread occurrence. The occurrence of microfilariae in cervicovaginal smears has seldom been reported, even as an accidental finding. In our retrospective study, four cases of clinically asymptomatic filariasis were diagnosed on a routine cervicovaginal Pap smear from January 2019 to July 2022. All microfilariae were characterized as Wuchereria bancrofti. In the present study, the majority of the cases present vaginal discharge, and the diagnosis was made by cytopathology. Therefore, it is crucial to consider and look for microfilariae in areas where they are not endemic.
Two Directing Groups Used for Metal Catalysed Meta‐C−H Functionalisation Only Effect Ortho Electrophilic C−H Borylation
Authors: Iqbal Saqib A. , Millet Clement R. P. , Pahl Jürgen , Yuan Kang , Ingleson Michael J. 
Published: October 2022

AbstractTwo templates used in meta‐directed C−H functionalisation under metal catalysis do not direct meta‐C−H borylation under electrophilic borylation conditions. Using BCl3 only Lewis adduct formation with Lewis basic sites in the template is observed. While combining BBr3 and the template containing an amide linker only led to amide directed ortho C−H borylation, with no pyridyl directed meta borylation. The amide directed borylation is selective for the ortho borylation of the aniline derived unit in the template, with no ortho borylation of the phenylacetyl ring – which would also form a six membered boracycle – observed. In the absence of other aromatics amide directed ortho borylation on to phenylacetyl rings can be achieved. The absence of meta‐borylation using two templates indicates a higher barrier to pyridyl directed meta borylation relative to amide directed ortho borylation and suggests that bespoke templates for enabling meta‐directed electrophilic borylation may be required.
Imagining the future of LGBTQ+ evaluation: New(er) directions and what comes next
Authors: Felt Dylan , Perez‐Bill Esrea , Barela Eric , Cundiff Nicole , Ellis Radaya , Johnson LaShaune , Metcalf Nicholas , Moore Travis Robert , Philliber Ash , Poirier Jeffrey , Rasher Sarah Daniel , Rizzo Cindy , Glenn Erik Elías , Phillips Gregory 
Published: October 2022

AbstractWe close this issue of New Directions for Evaluation by looking towards the future. In this chapter, the perspectives of 10 LGBTQ+ Evaluators whose voices and insights were not otherwise featured in this issue provide their critical insights on what LGBTQ+ Evaluation means to them, what it looks like in practice, and where they hope to see it grow in the future, including how the work of this issue of New Directions for Evaluation can be expanded and built upon. In closing the issue on a critical, futures‐oriented note, we reaffirm our assertion that this is neither the first, nor the final word on LGBTQ+ Evaluation, and we invite all evaluators to join in the process of articulating and exploring what LGBTQ+ Evaluation is, and can be.
Identity as a compass when navigating uncharted equitable spaces: Our queer evaluation practices
Authors: Hartman Andrew , Hoessler Brian , Tom Vincent , Camman C. 
Published: October 2022

AbstractAlternative approaches within evaluation increasingly allow space for evaluators to bring themselves to their work. As queers, we are gifted‐partially as a necessity for our survival‐with deeper understandings of and navigational capacities to work within complexity. Furthermore, existing as queer empowers us to think and operate outside what is the norm, known, familiar and comfortable, and thus enables us to challenge normative systems for purposes of social change. Our chapter offers situated insight into what queer evaluation practices look like and empowers us to practice bringing ourselves into different contexts, including uncharted spaces. We illustrate principles of queer evaluation through cases of our unique identities, contexts, landscapes, and evaluation experiences, within a process that is iterative, dialogic, and relational. We argue that the exploration of ourselves is critical as evaluators and invite readers to wander alongside us while actively searching their identities. Rather than hiding these biases and perspectives, we believe in the importance of knowing oneself and our connections to the histories of those who came before, which serve as our guides. Only from this point can we begin to unravel the unknown into the known and transform the inequitable into the equitable that has yet to exist. We argue that by embracing our identities we are better able to navigate the complexities that exist in our work and deepen our understanding of the contexts around us.
Select HDAC Inhibitors Enhance Osteolysis and Bone Metastasis Outgrowth but Can Be Mitigated With Bisphosphonate Therapy
Authors: Clements Miranda E , Holtslander Lauren , Johnson Joshua R , Johnson Rachelle W 
Published: October 2022

ABSTRACTBreast cancer has a high predilection for spreading to bone with approximately 70% of patients who succumb to disease harboring bone disseminated tumor cells. Despite this high prevalence, treatments for bone metastatic breast cancer predominantly manage morbidities, including pain and hypercalcemia, rather than reducing bone metastasis incidence or growth. Histone deacetylase inhibitors (HDACi), including panobinostat, entinostat, and valproic acid, typically slow primary tumor progression and are currently in clinical trials for the treatment of many cancers, including primary and metastatic breast cancer, but their effects on bone metastatic disease have not been examined in preclinical models. We report that treatment with the HDACi panobinostat, but not entinostat or valproic acid, significantly reduced trabecular bone volume in tumor‐naïve mice, consistent with previous reports of HDACi‐induced bone loss. Surprisingly, treatment with entinostat or panobinostat, but not valproic acid, increased tumor burden and incidence in an experimental model of breast cancer bone metastasis. In vitro, multiple HDACi stimulated expression of pro‐osteolytic genes in breast tumor cells, suggesting this may be a mechanism by which HDACi fuel tumor growth. In support of this, combination therapy of panobinostat or entinostat with the antiresorptive bisphosphonate zoledronic acid prevented bone metastatic progression; however, the addition of zoledronic acid to panobinostat therapy failed to fully correct panobinostat‐induced bone loss. Together these data demonstrate that select HDACi fuel bone metastatic growth and provide potential mechanistic and therapeutic avenues to offset these effects. © 2022 The Authors. JBMR Plus published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research.
Clinical features of patients with talaromycosis marneffei and microbiological characteristics of the causative strains
Authors: Peng Lei , Shi Yu‐bo , Zheng Lin , Hu Li‐qing , Weng Xing‐bei 
Published: October 2022

AbstractBackgroundTalaromyces marneffei (T. marneffei) is a temperature‐dependent dimorphic fungus that is mainly prevalent in Southeast Asia and South China and often causes disseminated life‐threatening infections. This study aimed to investigate the clinical features and improve the early diagnosis of talaromycosis marneffei in nonendemic areas.MethodsWe retrospectively analyzed the medical records of six cases of T. marneffei infection. We describe the clinical manifestations, laboratory tests, and imaging manifestations of the six patients.ResultsTalaromyces marneffei infection was confirmed by sputum culture, blood culture, tissue biopsy, and metagenomic next‐generation sequencing (mNGS). In this study, there were five disseminated‐type patients and two HIV patients. One patient died within 24 h, and the others demonstrated considerable improvement after definitive diagnosis.ConclusionsDue to the lack of significant clinical presentations of talaromycosis marneffei, many cases may be easily misdiagnosed in nonendemic areas. It is particularly important to analyze the imaging manifestations and laboratory findings of infected patients. With the rapid development of molecular biology, mNGS may be a rapid and effective diagnostic method.
Identification of Hypoderma actaeon (Diptera: Oestridae) in red deer (Cervus elaphus) from northern Spain: Microscopy study and molecular analysis
Authors: González Sara , Del Rio Maria Luisa , Diez Maria Natividad , Hidalgo Maria del Rosario , Martínez Angelica 
Published: October 2022

AbstractHypoderma spp. larvae were observed subcutaneously in the dorsal and lumbar regions of red deer (Cervus elaphus) hunted in the province of León (northwestern Spain) causing a myiasis. They were removed and initially classified by their size, shape, color, and location under the skin into the three larval stages that parasitize these animals. The morphological characteristics of the first and second‐instar are described and from the features of the third‐instar the species was identified as Hypoderma actaeon. To accurately identify this species, five isolates of genomic DNA from the third‐instar, two from the second‐instar and two from first‐instar of H. actaeon were analyzed by PCR analysis of the COI region of mt‐DNA. The results confirmed that the examined samples exactly matched with H. actaeon. This study has shown the morphological identification of the three larval stages of H. actaeon and, for the first time, the first and second‐instar larvae have been molecularly characterized. Finally, identification of only H. actaeon suggests that this species is the only affecting red deer in the Iberian Peninsula.
Surfactant‐free oleogel‐based emulsion stabilized by co‐assembled ceramide/lecithin crystals with controlled digestibility
Authors: Zhang Jing , Dong Lulu , Zheng Qianwang , Xiao Jie , Cao Yong , Lan Yaqi 
Published: October 2022

AbstractBACKGROUNDThere is increasing interest in the development of oleogel‐based emulsions. However, they usually contained surfactants for stabilization, especially small‐molecular weight surfactants, which may have adverse health impacts.RESULTSHerein, a surfactant‐free oleogel‐based emulsion stabilized by co‐assembled ceramide/lecithin (CER/LEC) crystals was developed. The formation and stabilization mechanisms were explored. The different molar ratios of gelator (LEC and CER) in emulsions resulted in different crystal morphology, crystallinity as well as different emulsion properties. This suggested that appropriate crystallinity, crystal size, and interfacial distribution of these crystals provided higher surface coverage against droplets coalescence, thus better emulsion stabilization. Both X‐ray diffractograms and contact angle results confirmed that the crystals which were primarily responsible for emulsion stabilization, are co‐assembled crystals consisted of both gelators (CER and LEC). Furthermore, the percentage of free fatty acids (FFAs%) results revealed a negative relationship between lipid digestibility and crystal concentration.CONCLUSIONSThis strategy greatly enriched surfactant‐free oleogel‐based emulsion formulations, as well as their potential applications in healthy lipid‐based products and novel food delivery systems with controlled lipid digestibility. © 2022 Society of Chemical Industry.
Radiochemical Ageing of ATH Filled Silane‐Crosslinked Polyethylene
Authors: Hettal Sarah , Roland Sébastien , Colin Xavier 
Published: October 2022

AbstractThis study focuses on the degradation of a silane cross‐linked polyethylene (Si‐XLPE) matrix filled with three different aluminum tri‐hydrate (ATH) contents: 0, 25, and 50 phr. These materials are subjected to radiochemical ageing in air under three different dose rates (8.5, 77.8, and 400 Gy h−1) at two temperatures (47 and 21°C). Changes due to ageing have been investigated by FTIR spectroscopy, DSC analysis, and density measurements in order to more precisely define their chemical composition and microstructure and to evidence the possible influence of ATH fillers on the oxidation kinetics of the Si‐XLPE matrix.
Analytic Methods of Foamed Plastic Insulation Deteriorated by Moisture
Authors: Leem Yoobin , Kojima Sizuka , Kitagaki Ryoma 
Published: October 2022

AbstractFoamed plastic insulations installed into buildings are now expected to be long‐lasting materials. However, in recent years, it has been reported that foamed plastic insulations installed in high‐humid environments, such as under waterproof sheets on a rooftop, absorb moisture, and subsequently increase thermal conductivity. This paper studies both moisture absorption and changes in physical properties of foamed plastic insulations after exposure to high humidity and discusses the moisture‐induced deterioration based on the results of several experiments.
Thermomechanical Characterization of E‐Glass Fiber Reinforced Random Polypropylene
Authors: Delli Evangelia , Gkiliopoulos Dimitrios , Bikiaris Dimitrios , Chrissafis Konstantinos 
Published: October 2022

AbstractThe thermomechanical properties of short glass fiber (GF) reinforced polypropylene random copolymer (PPR) composites are investigated. Four composites with different fiber content, namely 10, 15, 20, and 30 wt%, are prepared using melting mixing. For fibers up to 15 wt% the composites exhibit enhanced thermal stability as compared to the random polypropylene. The use of fibers also improve the mechanical strength of the matrix. In particular, PPR/GF30% demonstrates the highest Young modulus, yield strength, and storage modulus values, while PPR/GF10% has the best ductility among the composites. Incorporation of 10 wt% fibers also increases the yield strength and storage modulus of the PPR matrix by approximately 1.6 and 1.2 (for temperatures higher than 60°C) times, respectively. These results suggest that GF reinforced PPR is a composite suitable for advanced technological applications.
Gate‐to‐Gate Study for Collaborative Robot‐Assisted Composite Parts Manufacturing Using a Work Effort Unit Approach
Authors: Salles Ana , Reichert Thomas , Ruiz Ana Maria , Cordero Jorge 
Published: October 2022

AbstractThis work presents one example from a set of technologies that aim at improving the efficiency of manufacturing processes of aircraft components in one of Airbus Defence and Space plants in regards to environmental aspects. Among the proposed technologies, one relates to the automation of two key manufacturing steps of the reference technology in the composite manufacturing of omega stringers: 1) lamination of main omega stringer structure through an Automated Fiber Placement robotic process; and 2) cobotic pick‐and‐place process for Carbon Fiber Reinforced Polymer patches. To evaluate potential environmental benefits, Fraunhofer performs a gate‐to‐gate study using as main parameter the “Work effort unit,” in this case representing the average energy consumption per productive hour in a typical assembly factory. When comparing the results for the composite part manufacturing by hand lay‐up with the use of collaborative robots, the key technical parameter is the reduction in lead time. While production using robots consume additional electricity when compared to human workers, automation significantly shortens lead times (‐74%), resulting in lower energy consumption per manufactured unit. The results indicate that this new technology from Airbus Defence and Space can potentially improve the overall environmental performance of composite parts during their manufacture.