bluuebunny/crossref_metadata_2025_split huggingface dataset:
Money laundering in corruption cases in Indonesia
Authors: Meiryani Meiryani , Isa Sani Muhamad , Kerta Johan Muliadi 
Published: July 2022

Purpose
In the case of money laundering (ML) originating from the predicate crime of corruption, law enforcers find it difficult to prove all or the existence of a predicate crime on assets that produce assets. This paper aims to analyze ML in corruption cases in Indonesia.

Design/methodology/approach
This research uses qualitative descriptive methods. This research discusses the law enforcement of corruption which coincides with the crime of ML.

Findings
New findings were discovered where against the corruption case which was carried out concurrently with the crime of money laundering, the value of which was Rp. 1bn and above and has been handled by investigators from the Corruption Eradication Commission (KPK), so the prosecution process is carried out by the public prosecutor from the KPK to continue the trial to the Corruption Court. With respect to cases of criminal acts of corruption, which were carried out concurrently with ML crimes, the value of which was Rp. 1bn and below and had been handled by the prosecutor’s investigators from the start, the prosecution process was carried out by the public prosecutor from the prosecutor’s office to continue the trial to the corruption court.

Originality/value
To the best of the authors’ knowledge, this is the first study to use normative perspective on ML in corruption cases (white-collar crime). In contrast to previous studies that take fraud in general as an object of research, researchers are now interested in focusing more research on detecting suspected ML crimes: a case study on corruption cases in Indonesia.
Leader humility, leader authenticity and informal learning: how humble team leaders model everyday workplace learning
Authors: Rigolizzo Michele , Zhu Zhu , Harvey Jean-François 
Published: July 2022

PurposeThis study aims to empirically examine the relationship between the leader characteristic of humility and the informal learning of team members. It also evaluates the role of leader authenticity in mediating that relationship.Design/methodology/approachData were collected on 518 salespeople reporting to 66 managers in a time-lagged study of a financial services firm. Generalized structural equation modeling was used to analyze the data and test a multi-hierarchical mediation model.FindingsLeader humility has a significant positive direct and indirect effect on individual informal learning in team contexts, and leader authenticity partially mediates this relationship.Research limitations/implicationsThis study advances research on how leaders can help transform learning from a risky endeavor to a daily practice. It shows the impact of the leadership characteristic of humility and explains how humble behaviors provide a model for individual learning in team contexts. It also reveals that leader authenticity is a key mechanism through which leader humility comes to influence employees’ informal learning within work teams.Originality/valueThis study provides empirical support for the importance of leader humility in engendering the trust required for employees to engage in everyday workplace learning. It integrates social information processing theory with social learning theory to show that humble leaders provide critical information about the value, cost and methods of individual informal learning in team contexts. Leader humility increases employees’ beliefs that they can and do learn from working in teams because employees perceive the humble leader’s behaviors as representing the leader’s true intentions.
Resilience concepts in integrated urban transport: a comprehensive review on multi-mode framework
Authors: Du Yuchuan , Wang Han , Gao Qian , Pan Ning , Zhao Cong , Liu Chenglong 
Published: July 2022

PurposeResilience concepts in integrated urban transport refer to the performance of dealing with external shock and the ability to continue to provide transportation services of all modes. A robust transportation resilience is a goal in pursuing transportation sustainability. Under this specified context, while before the perturbations, robustness refers to the degree of the system’s capability of functioning according to its design specifications on integrated modes and routes, redundancy is the degree of duplication of traffic routes and alternative modes to maintain persistency of service in case of perturbations. While after the perturbations, resourcefulness refers to the capacity to identify operational problems in the system, prioritize interventions and mobilize necessary material/ human resources to recover all the routes and modes, rapidity is the speed of complete recovery of all modes and traffic routes in the urban area. These “4R” are the most critical components of urban integrated resilience.Design/methodology/approachThe trends of transportation resilience's connotation, metrics and strategies are summarized from the literature. A framework is introduced on both qualitative characteristics and quantitative metrics of transportation resilience. Using both model-based and mode-free methodologies that measure resilience in attributes, topology and system performance provides a benchmark for evaluating the mechanism of resilience changes during the perturbation. Correspondingly, different pre-perturbation and post-perturbation strategies for enhancing resilience under multi-mode scenarios are reviewed and summarized.FindingsCyber-physic transportation system (CPS) is a more targeted solution to resilience issues in transportation. A well-designed CPS can be applied to improve transport resilience facing different perturbations. The CPS ensures the independence and integrity of every child element within each functional zone while reacting rapidly.Originality/valueThis paper provides a more comprehensive understanding of transportation resilience in terms of integrated urban transport. The fundamental characteristics and strategies for resilience are summarized and elaborated. As little research has shed light on the resilience concepts in integrated urban transport, the findings from this paper point out the development trend of a resilient transportation system for digital and data-driven management.
Efficacy and safety of baricitinib for the treatment of moderate‐to‐severe atopic dermatitis: A systematic review and meta‐analysis of randomized clinical trials
Authors: Wang Bin , Pan Shuaixi , Yao Yue , Zeng Linxi , Zhang Guoqiang 
Published: July 2022

AbstractAtopic dermatitis (AD) is one of the most prevalent inflammatory skin diseases. Janus kinase (JAK) inhibitor baricitinib is a promising treatment for AD as shown in recent clinical trials. We conducted a systematic review and meta‐analysis of randomized controlled trials (RCTs) reporting the efficacy and safety of baricitinib. Data analysis was carried out using Cochrane Collaboration Review Manager 5.4 software and performed as risk ratios (RR) with 95% confidence intervals. Six RCTs involving a total of 2595 patients were included in the review. The meta‐analysis revealed that patients in the baricitinib group had significantly higher rates achieving EASI75, EASI90, IGA‐Response, SCORAD75, and Itch NRS improvement. Pooled analysis also showed no significant differences in treatment of emergent adverse events (TEAEs) between baricitinib and placebo groups. In conclusion, our meta‐analysis showed that baricitinib has promising efficacy for moderate‐to‐severe AD with favourable safety files.
Investigating the microbial community of Cacopsylla spp. as potential factor in vector competence of phytoplasma
Authors: Schuler Hannes , Dittmer Jessica , Borruso Luigimaria , Galli Jonas , Fischnaller Stefanie , Anfora Gianfranco , Rota‐Stabelli Omar , Weil Tobias , Janik Katrin 
Published: July 2022

AbstractPhytoplasmas are obligatory intracellular bacteria that colonize the phloem of many plant species and cause hundreds of plant diseases worldwide. In nature, phytoplasmas are primarily transmitted by hemipteran vectors. While all phloem‐feeding insects could in principle transmit phytoplasmas, only a limited number of species have been confirmed as vectors. Knowledge about factors that might determine the vector capacity is currently scarce. Here, we characterized the microbiomes of vector and non‐vector species of apple proliferation (AP) phytoplasma ‘Candidatus Phytoplasma mali’ to investigate their potential role in the vector capacity of the host. We performed high‐throughput 16S rRNA metabarcoding of the two principal AP‐vectors Cacopsylla picta and Cacopsylla melanoneura and eight Cacopsylla species, which are not AP‐vectors but co‐occur in apple orchards. The microbiomes of all species are dominated by Carsonella, the primary endosymbiont of psyllids and a second uncharacterized Enterobacteriaceae endosymbiont. Each Cacopsylla species harboured a species‐specific phylotype of both symbionts. Moreover, we investigated differences between the microbiomes of AP‐vector versus non‐vector species and identified the predominant endosymbionts but also Wolbachia and several minor taxa as potential indicator species. Our study highlights the importance of considering the microbiome in future investigations of potential factors influencing host vector competence. We investigated the potential role of symbiotic bacteria in the acquisition and transmission of phytoplasma. By comparing the two main psyillid vector species of Apple proliferation (AP) phytoplasma and eight co‐occurring species, which are not able to vector AP‐phytoplasma, we found differences in the microbial communities of AP‐vector and non‐vector species, which appear to be driven by the predominant symbionts in both vector species and Wolbachia and several minor taxa in the non‐vector species. In contrast, infection with AP‐phytoplasma did not affect microbiome composition in both vector species. Our study provides new insights into the endosymbiont diversity of Cacopsylla spp. and highlights the importance of considering the microbiome when investigating potential factors influencing host vector competence.
The modification of volatile and nonvolatile compounds in lupines and faba beans by substrate modulation and lactic acid fermentation to facilitate their use for legume‐based beverages—A review
Authors: Ritter Stefan W. , Gastl Martina I. , Becker Thomas M. 
Published: July 2022

AbstractLupines and faba beans are promising ingredients for the beverage industry. They contain high amounts of protein and can be grown in different climate zones and agricultural areas. Therefore, these legumes appear as ideal raw material for vegan, functional, and sustainable beverages. Nevertheless, the sensory characteristic of legumes is generally not accepted in beverages. Therefore, the market contribution of legume‐based beverages is currently only marginal. This review highlights known major flavor aspects of lupines and faba beans and the possibilities to improve these by germination, heat treatment, enzymatic treatment, and subsequent lactic acid fermentation. First, the main aroma and taste compounds are described. Thereby, the “beany” aroma is identified as the most relevant off‐flavor. Second, the nutrients and antinutrients of these legumes regarding to their use as food and as substrate for lactic acid fermentation are reviewed, and possibilities to modulate the substrate are summarized. Finally, the modification of the sensory profile by lactic acid fermentation is outlined. To conclude, it seems likely that the nutritional and flavor attributes in legume‐based beverages can be improved by a combined process of substrate modulation and fermentation. In a first step, antinutrients should be decomposed and proteins solubilized while transforming the solid grains into a liquid substrate. Due to such substrate modulation, a broader variety of strains could be employed and the fermentation could be based exclusively on their impact on the flavor. By applying the concept of combining a substrate modulation with a subsequent fermentation, the use of legumes in beverages could be facilitated and new products like vegan, protein‐rich, refreshing beverages could be marketed.
Rare vascular involvement in Behçet's disease: Coronary artery pseudoaneurysm
Authors: Karabulut Mehmet Nuri , Topcu Ahmet Can , Erkul Sinan , Kayalar Nihan 
Published: July 2022

AbstractBehçet's disease is a relapsing, inflammatory, multi‐systemic disease. Coronary arterial involvement in Behçet's disease is very rare with a prevalence of less than 0.5%. We report the case of a 34‐year‐old man who presented with a coronary artery pseudoaneurysm associated with Behçet's disease. The patient underwent a successful left internal thoracic artery to left anterior descending artery bypass graft procedure, and remains symptom‐free in a 6‐month follow up with normal electrocardiogram.
Evaluation and redesign of the primers for detecting nitrogen cycling genes in environments
Authors: Wang Zhujun , Feng Kai , Wei Ziyan , Wu Yueni , Isobe Kazuo , Senoo Keishi , Peng Xi , Wang Danrui , He Qing , Du Xiongfeng , Li Shuzhen , Li Yan , Deng Ye 
Published: July 2022

Abstract

A better understanding of how nitrogen (N) cycling genes are involved in ecological processes is one of the crucial areas of microbial ecology. Currently, most molecular biological techniques investigating N cycling genes in the environment heavily rely on the accuracy of the polymerase chain reaction (PCR) primers; however, their specificity and coverage have not been comprehensively evaluated. Here, we collected a sequence database, NcycFunGen, aimed for primer evaluation and redesign.

NcycFunGen was based on hidden Markov model profiles for 22 marker genes involved in N cycling, which included 607,359 paired nucleotide and protein sequences with their taxonomic information. Then, a total of 608 published primers were fully evaluated through NcycFunGen, as well as against full‐length sequences collected from KEGG. The new primers were designed by DegePrime. In the experiment, the updated ureC gene primer pair ureC607F/ureC898R and nifH gene primer pair nifH107F64/nifH379R64 was applied to a urea amendment site using droplet digital PCR and high‐throughput amplicon sequencing.

The results showed that the majority of primer pairs cover less than 30% sequences of target genes and that 22.55% were inappropriate for quantitative PCR and amplicon sequencing (<100 bp or >550 bp). In general, this in‐silico evaluation demonstrated that although many primers have been adopted in published studies, some of them should be validated and updated as needed according to the updated gene database. Therefore, new degenerate primer pairs for ureC targeting urease, bacterial and archaeal amoA targeting ammonium monooxygenase, and nifH targeting nitrogenase were designed through NcycFunGen. These new primer pairs showed higher coverage and amplification efficiency, as well as amplicon lengths that were applicable for high‐throughput amplicon sequencing. Furthermore, the experimental results displayed better characteristics than commonly used published ureC and nifH gene primer pairs.

In conclusion, primer evaluation and redesign are highly recommended to improve the accuracy of primers targeting N cycling genes, which could facilitate amplicon‐based N cycling studies in various environments. The bioinformatics framework developed in this study can also be applied to build functional gene databases for other biogeochemical pathways.
Diagnostic accuracy of neuroimaging in emergency department patients with acute vertigo or dizziness: A systematic review and meta‐analysis for the guidelines for reasonable and appropriate care in the emergency department
Authors: Shah Vishal Paresh , Oliveira J. e Silva Lucas , Farah Wigdan , Seisa Mohamad , Kara Balla Abdalla , Christensen April , Farah Magdoleen , Hasan Bashar , Bellolio Fernanda , Murad M. Hassan 
Published: July 2022

AbstractBackgroundPatients presenting to the emergency department (ED) with acute vertigo or dizziness represent a diagnostic challenge. Neuroimaging has variable indications and yield. We aimed to conduct a systematic review and meta‐analysis of the diagnostic test accuracy of neuroimaging for patients presenting with acute vertigo or dizziness.MethodsAn electronic search was designed following patient–intervention–control–outcome (PICO) question—(P) adult patients with acute vertigo or dizziness presenting to the ED; (I) neuroimaging including computed tomography (CT), CT angiography (CTA), magnetic resonance imaging (MRI), magnetic resonance angiography (MRA), and ultrasound (US); (C) MRI/clinical criterion standard; and (O) central causes (stroke, hemorrhage, tumor, others) versus peripheral causes of symptoms. Articles were assessed in duplicate. The Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines were followed. Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) was used to assess certainty of evidence in pooled estimates.ResultsWe included studies that reported diagnostic test accuracy. From 6309 titles, 460 articles were retrieved, and 12 were included: noncontrast CT scan—six studies, 771 patients, pooled sensitivity 28.5% (95% confidence interval [CI] 14.4%–48.5%, moderate certainty) and specificity 98.9% (95% CI 93.4%–99.8%, moderate certainty); MRI—five studies, 943 patients, sensitivity 79.8% (95% CI 71.4%–86.2%, high certainty) and specificity 98.8% (95% CI 96.2%–100%, high certainty); CTA—one study, 153 patients, sensitivity 14.3% (95% CI 1.8%–42.8%) and specificity 97.7% (95% CI 93.8%–99.6%), CT had higher sensitivity than CTA (21.4% and 14.3%) for central etiology; MRA—one study, 24 patients, sensitivity 60.0% (95% CI 26.2%–87.8%) and specificity 92.9% (95% CI 66.1%–99.8%); US—three studies, 258 patients, sensitivity ranged from 30% to 53.6%, specificity from 94.9% to 100%.ConclusionsNoncontrast CT has very low sensitivity and MRI will miss approximately one in five patients with stroke if imaging is obtained early after symptom onset. The evidence does not support neuroimaging as the only tool for ruling out stroke and other central causes in patients with acute dizziness or vertigo presenting to the ED.
School performance and later diagnoses of nonaffective psychoses, bipolar disorder, and depression
Authors: Gyllenberg David , Ristikari Tiina , Kelleher Ian , Kääriälä Antti , Gissler Mika 
Published: July 2022

AbstractObjectiveIt is unclear whether there are differences between specific school subject performance and later psychiatric disorders. We examined whether mean grade point average (MGPA) and specific school subjects associated with diagnoses of nonaffective psychoses, bipolar disorder and depression.MethodsIn this register‐based study, we studied the Finnish population born in 1987 who had available MGPA and six specific school grades (age = 15.4–16.4 years; n = 50,508). Grades were analyzed with smoothing splines. Covariates included sex, urbanicity, parental education level and parental diagnosed psychiatric disorders. Outcomes were incident nonaffective psychosis, bipolar disorder and depression diagnosed in specialized services until year 2015 (age = 28.0–28.9 years).ResultsDuring the follow‐up, 727 individuals were diagnosed with nonaffective psychoses, 489 with bipolar disorder and 3492 with depression. MGPA was inversely associated with all outcomes. In multivariate models including specific school subjects and covariates, the school subject with largest risk ratios (RR) was Physical Education (RR and Bonferroni‐corrected confidence interval [CI] at −1.5 SD: nonaffective psychoses 1.63, 1.36–1.95; bipolar disorder 1.64, 1.30–2.05; depression 1.72, 1.53–1.93). Higher grades in Art were associated with nonaffective psychoses and depression (RR and Bonferroni‐corrected CI at +1.5 SD: nonaffective psychoses 1.48, 1.11–1.96; depression 1.22, 1.07–1.38).ConclusionThere was a robust association between poorer scores on Physical Education and risk for psychosis, bipolar disorder and depression. Higher grades in Art were also associated with risk for later disorders. Subject specific school performance may be more informative about mental disorder risk than overall school performance.
Novel color fluorescence imaging for sentinel lymph node detection in oral and oropharyngeal cancer
Authors: Miyamoto Shunsuke , Nakayama Meijin , Kano Koichi , Tsutsumi Shohei , Momiyama Kaho , Matsuki Takashi , Yamashita Taku 
Published: July 2022

AbstractAimFluorescence imaging (FI) using indocyanine green (ICG) is a noteworthy alternative technique for sentinel lymph node (SLN) detection without radiation exposure in oral cavity and oropharynx cancer. However, conventional FI is monochrome, so the visibility is limited. This study assessed whether color FI using the HyperEye Medical System (HEMS) is feasible as an alternative for SLN detection.MethodsPatients with previously untreated cT1‐2N0 oral or oropharyngeal cancer who were to undergo primary tumor resection and elective neck dissection (END) in our hospital were enrolled from November 2012 to March 2016. The patients underwent SLN detection for biopsy via the HEMS following the injection of ICG solution around the primary lesion before neck dissection. The visibility and the diagnostic accuracy of the imaging were evaluated.ResultsSLNs were visualized in all eight cases; however, transcutaneous fluorescence detection was not observed in all cases. Utilizing color mode imaging simplified harvest by clearly discriminating SLNs from surrounding structures, while the monochrome mode proved to be more sensitive for detection. Two cases showed occult metastases on both sentinel and regional nodes. The identification and false negative rates were 100% and 0%, respectively. There were no complications incurred due to this method.ConclusionOur results suggest that color FI with the HEMS allows for the accurate and safe harvest of SLNs with a preparatory skin incision. Although there is room for improvement of sensitivity, this easy‐to‐handle procedure might provide the potential to expand the role of the ICG method for SLN detection in head and neck cancer.