bluuebunny/crossref_metadata_2025_split huggingface dataset:
992-P: Pediatric Diabetes Providers Are Poorly Adherent to the ADA Treatment Guidelines for New-Onset Type 2 Diabetes (T2D)
Authors: SAID JERIES H. , WOLFGRAM PETER , CABRERA SUSANNE M. 
Published: May 2022

Since 2018, the ADA Standards of Medical Care has provided evidence-based treatment guidelines for clinically suspected youth-onset T2D. We hypothesized adherence of pediatric diabetes providers to these guidelines was poor. We conducted a retrospective chart review of new onset T2D youth seen for initial consultation at our multidisciplinary tertiary care pediatric diabetes clinic. Between 7/20 and 6/2020, 90 youth completed initial visits: mean initial HbA1c 9.7% (6.5-14%) , mean age of 14.5 (range 9-19) , 57% female, 85% English-speaking, 60% Black, 10% Non-Hispanic White, and 27% Hispanic. Forty-one had an initial HbA1c &lt;8.5% without acidosis, with 34 of these 41 (83%) started on metformin, in accordance with ADA guidelines. Four of the 41 (10%) patients were started on insulin therapy; these 4 had higher HbA1c than those started on metformin alone (8.1% vs. 6.7%, p = 0.0003) . In contrast, 49 of the 90 patients presented with an initial HbA1c ≥8.5% without acidosis. Of these 49, 6 (12%) were started on metformin and basal insulin, in accordance with ADA guidelines; however, the basal insulin was dosed at a mean of 0.27 unit/kg (0.20-0.45) rather than the recommended 0.5 unit/kg. Metformin with basal + prandial insulin was started in 23 (47%) . Sixteen of 49 (33%) were started on basal (0.20 unit/kg) + prandial insulin without metformin. Notably, in patients with HbA1c ≥8.5%, initial treatment choice did not differ by age, HbA1c, or race/ethnicity. Overall, providers exhibited greater fidelity to ADA treatment recommendations in those with HbA1c &lt; 8.5% (83% adherence) than those with HbA1c ≥ 8.5% (12%) . In 80% of patients with a HbA1c ≥ 8.5, providers appeared to default to typical T1D treatment with an initial basal dose of 0.2 unit/kg and inclusion of prandial insulin. These findings demonstrate poor adherence to youth-onset T2D guidelines. A quality improvement project is underway to reduce practice variance and optimize the care of youth with newly diagnosed T2D.

Disclosure
J.H.Said: None. P.Wolfgram: n/a. S.M.Cabrera: None.

Funding
American Diabetes Association (1-18-ICTS-094)
995-P: LRG1 Mediates Diet-Induced Hyperinsulinemia by Enhancing Glucose-Stimulated Insulin Secretion
Authors: MORALES DESIRAE , RYU JIYOON , LYNCH JANE L. , DUGGIRALA RAVINDRANATH , DONG LILY Q. 
Published: May 2022

Childhood obesity and metabolic syndrome sequelae associated with early-onset insulin resistance and type 2 diabetes are at epidemic levels globally with increasing evidence for worrisome young adult health sequelae trajectories. Pediatric obesity is often associated with dramatic rise in hyperinsulinemia and acanthosis during puberty, a risk for progression to type 2 diabetes and/or hepatic steatosis. Recently, we reported leucine-rich alpha-2-glycoprotein 1 (LRG1) as an adipokine, which levels in sera are positively associated with BMI in humans. LRG1 binds with multiple metabolic organs in vivo, including the liver and pancreas. Deletion of the Lrg1 gene in mice alleviates high-fat diet (HFD) -induced hyperinsulinemia, hepatosteatosis, insulin resistance, and obesity at a young age. Our current study indicates that treating the MIN6 beta-cells with LRG1 was sufficient to trigger insulin secretion both in the absence and presence of glucose in a dose-dependent manner, specifically enhancing the first phase of insulin secretion. We also identified an LRG1 monoclonal antibody that neutralizes LRG1-related stimulation of insulin secretion in MIN6 beta-cells. Serum levels of LRG1 in young mice fed with HFD led to enhanced levels of LRG1 in sera in these mice, which preceded hyperinsulinemia and subsequent increased weight gain. Together, our results reveal that up-regulated LRG1 in circulation could be a causal factor for persistent hyperinsulinemia by directly targeting pancreatic beta-cells to enhance insulin secretion in childhood obesity and a likely biomarker for early childhood hyperinsulinemia and treatment assessments. Understanding the impact of LRG1 on childhood obesity provides critical information to prevent early-stage insulin resistance and type 2 diabetes.

Disclosure
D.Morales: None. J.Ryu: None. J.L.Lynch: Consultant; Novo Nordisk, Novo Nordisk, Novo Nordisk, Research Support; Beta Bionics, Inc., Beta Bionics, Inc., Beta Bionics, Inc., Jaeb Center for Health Research, Jaeb Center for Health Research, Jaeb Center for Health Research. R.Duggirala: None. L.Q.Dong: None.
MSME PERFORMANCE EFFECTIVENESS DURING COVID 19 PANDEMIC PERIOD
Authors: Hariadi Hariadi , Humairoh Fitri , Desmiyawati Desmiyawati , Azlina Nur 
Published: May 2022

This research aims at examining the influence of the effect of e-commerce, innovation and accounting information systems on the MSMEs’ performance in the Bengkalis district. The population method used in this research was MSMEs in Bengkalis district. The samples in this research were 100 MSMEs that fit the criteria that have been determined. The data used in this research was primary data with a questionnaire as an instrument. Additionally, the data collection in this research used purposive sampling, where the total number of respondents in this research was 100 respondents. The data analysis was done with a multiple linear regression model with Statistical Product and Service Solution (SPSS) software 25.0 version. The results obtained were e-commerce, inovation and accounting information systems that had a significant effect on MSMEs' performance.
Penggunaan Media Interaktif Dengan Pembelajaran Model Assure Untuk Meningkatkan Kemampuan Komuniasi Matematis Dan Pemecahan Masalah Serta Self Confidence Siswa Pada Materi Bangun Ruang Sisi Lengkung
Authors: Rosnawati Popon 
Published: May 2022

Penelitian ini bertujuan untuk mengkaji peningkatan kemampuan Komunikasi Matematis dan Pemecahan Masalah serta Self Confidence Siswa kelas IX pada materi bangun ruang sisi lengkung dengan penggunaan media interaktif dalam pembelajaran model ASSURE ditinjau berdasarkan nilai KAM (Kemampuan Awal Matematika). Penelitian ini menggunakan metode campuran (Mixed Methods), dan penelitian ini adalah penelitian tindakan kelas yang terdiri dari 6 pertemuan dalam tiga siklus. Dengan subjek penelitian siswa kelas IX SMP Negeri 5 Sumedang sebanyak 3 kelas. Instrumen yang digunakan adalah instrumen tes kemampuan komunikasi dan pemecahan masalah, instrumen non tes lembar observasi, angket dan hasil wawancara, dan nilai PAT kelas VIII semester 2 dijadikan sebagai KAM. Berdasarkan hasil penelitian diperoleh kesimpulan bahwa: secara keseluruhan Pembelajaran model ASSURE dapat meningkatkan kemampuan komunikasi matematis dan pemecahan masalah serta self confidence siswa pada KAM berkategori tinggi dan rendah. Penggunaan media interaktif dengan pembelajaran model ASSURE dapat meningkatkan kemampuan komunikasi matematis dan pemecahan masalah serta self confidence siswa pada siswa berkategori KAM tinggi dan rendah. Adanya perbedaan peningkatan kemampuan komunikasi matematis dan pemecahan masalah matematis antara siswa yang mendapat Pembelajaran model ASSURE, siswa yang mendapatkan Pembelajaran penggunaan media interaktif dengan model ASSURE dan siswa yang mendapatkan Pembelajaran Konvensional. Terdapat peningkatan self confidence siswa antara siswa yang mendapatkan Pembelajaran model ASSURE dan siswa yang mendapatkan penggunaan media interaktif dengan pembelajaran model ASSURE, dari siswa yang mendapatkan Pembelajaran konvensional. Terdapat korelasi dengan kategori baik antara kemampuan komunikasi matematis dan kemampuan pemecahan masalah serta Self Confidence siswa dimana semakin tinggi tingkat kemampuan komunikasi matematis dan kemampuan pemecahan masalah matematis akan semakin tinggi self confidence siswa. Namun demikian kondisi korelasi dapat terganggu dengan beberapa faktor diantaranya, ketidakmampuan siswa untuk konsentrasi, keadaan kondisi sosial dan ekonomi, serta kurangnya kemampuan guru dalam menyampaikan materi.
Penerapan Model Student Teams-Achievment Division (STAD) Berbantu Alat Permainan Pecahan Untuk Meningkatkan Hasil Belajar Siswa Mata Pelajaran Matematika Materi Pecahan Semester II Kelas IV SD 2 Padurenan Kecamatan Gebog Kabupaten Kudus
Authors: Fatkhiyah Noor 
Published: May 2022

In general, action research aims to improve mathematics learning outcomes with the subject matter of simplifying fractions Elementary School fourth grade students 2 Padurenan Gebog Kudus in the Academic Year 2017/2018. Learning model used is Student Teams-Achievement Division (STAD) with a subject of research students 2 Padurenan Elementary School fourth grade and time studies conducted over three months consisted of two cycles. Each cycle consists of planning, implementation, observation and reflection. Data collection tool using written tests and non-test. While the techniques of data analysis using qualitative analysis techniques. The results showed learning model STAD can improve student learning outcomes. It can be seen from the increase in average student learning outcomes of the initial condition for 55.56 increased to 67.78 in Cycle 1 with a passing grade of 61.11%, and in cycle 2 to 78.33 with a passing grade of 77, 78%.
Meningkatkan Karakter Siswa Melalui Layanan Bimbingan Klasikal Dengan Pendekatan Holistik
Authors: Setiyati Setiyati 
Published: May 2022

Berdasarkan seluruh kegiatan penelitian tindakan bimbingan konseling dapat disimpulkan bahwa karakter siswa SMP Negeri 2 Susukan Semarang dapat ditingkatkan melalui layanan bimbingan klasikal dengan pendekatan holistic, dengan hasil sebagai berikut: (1) Berdasarkan hasil observasi aktivitas siswa dalam layanan bimbingan klasikal dengan pendekatan holistik siklus I mencapai rata-rata 76,3% pada kategori cukup dan pada siklus II mencapai rata-rata 84,4%pada kategori baik, (2) Tingkat karakter anak pada kondisi awal secara klasikal rata-rata adalah 66,81 pada kategori cukup baik. Tingkat karakter anak siklus I secara klasikal rata-rata adalah 73,59 pada kategori cukup baik. Peningkatan karakter siswa secara klasikal sebesar 6,78%. Tingkat karakter anak siklus II secara klasikal adalah 80,70 pada kategori baik. Peningkatan karakter siswa secara klasikal sebesar 7,11%, (3) Berdasarkan indeks keberhasilan kinerja, pada Kondisi Awal karakter siswa kelas 8 D SMP Negeri 2 Susukan, Kabupaten Semarang yang mencapai skor ≥ 70 ada 9 siswa (33,3%). Pada siklus I yang mencapai skor ≥ 70 ada 21 siswa (77,8%) belum mencapai 80% secara klasikal, sehingga dilakukan tindak lanjut berupa pelayanan siklus II. Peningkatan indeks kinerja sebesar 44,4%. Pada siklus II yang mencapai skor ≥ 70 ada 26 siswa (96,37%) sudah mencapai 80% secara klasikal. Peningkatan indeks kinerja sebesar 22,7%.
Peningkatan Pemahaman Konsep Melalui Model Contextual Teaching And Learning Berbantuan Media Kotak Lingkungan Hewan Pada Tema 6 Kelas IV SD 1 Bakalan Krapyak
Authors: Rohmah Sri Ainur , Fakhriyah Fina , Ardianti Sekar Dwi 
Published: May 2022

Penelitian ini bertujuan untuk meningkatkan keterampilan guru, aktivitas siswa (aktivitas afektif dan psikomotorik), dan pemahaman konsep siswa dengan menerapkan model Contextual Teaching And Learning pada mata pelajaran Bahasa Indonesia dan IPA di SD 1 Bakalan Krapyak Kudus. Penelitian ini merupakan Penelitian Tindakan Kelas (PTK) yang dilaksanakan di kelas IV . Metode pengumpulan data meliputi observasi, wawancara, tes, dan dokumentasi. Hasil penelitian menunjukkan pembelajaran Bahasa Indonesia dan IPA melalui model Contextual Teaching And Learning berbantuan media kotak lingkungan hewan meningkat setiap siklusnya. Nilai Rata-rata keterampilan guru siklus I yakni 67 (perlu bimbingan), kemudian meningkat pada siklus II dengan nilai rata-rata 87,09 (baik). Nilai rata-rata aktivitas afektif siklus I dengan nilai 71,27 (perlu bimbingan), siklus II meningkat menjadi 88,01 (baik). Nilai rata-rata aktivitas psikomotorik siklus I dengan nilai 74,89 (perlu bimbingan), siklus II meningkat menjadi 86,3 (baik). Nilai rata-rata pemahaman konsep pada siklus I nilai rata-rata 72,58 (perlu bimbingan), meningkat pada siklus II menjadi 85,95 (baik).
Penerapan Konseling Behavioristik Teknik Operant Conditioning untuk Mengatasi Prokrastinasi Siswa
Authors: Nurzulian Ulfa Aulia , Rahardjo Susilo , Zamroni Edris 
Published: May 2022

Tujuan penelitian ini adalah: 1. Untuk mengetahui faktor-faktor yang menyebabkan prokrastinasi siswa kelas XI IPS 2 SMA 2 Kudus tahun ajaran 2017/2018, 2. Untuk mengatasi prokrastinasi siswa kelas XI IPS 2 SMA 2 Kudus tahun ajaran 2017/2018. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian kualitatif yang dirancang dalam bentuk studi kasus. Subjek yang diteliti yaitu AAP, AJR, dan SDP siswa kelas XI IPS 2 SMA 2 Kudus tahun ajaran 2017/2018 yang mengalami prokrastinasi. Teknik pengumpulan data yang dilakukan adalah: 1) Wawancara, 2) Observasi, 3) Dokumentasi. Analisis yang digunakan dalam penelitian ini adalah induktif. Adapun cara menganalisis data dalam penelitian ini dilakukan secara sistematis mulai dari proses pengumpulan data, mengklarifikasi, mengdeskripsikan, dan menginterpretasikan masing-masing bagian. Dengan menggunakan konseling behavioristik teknik operant conditioning dapat menghasilkan perubahan tingkah laku pada klien untuk mampu memulai mengerjakan tugas, mampu menyelesaikan tugas yang telah dikerjakan, cepat dalam mengerjakan tugas, mengumpulkan tugas tepat waktu, dan mendahulukan mengerjakan tugas daripada melakukan aktifitas lain.
Meningkatkan Sikap Anti Seks Bebas Melalui Layanan Bimbingan Kelompok Teknik Homeroom
Authors: Umiiyati Fitri 
Published: May 2022

Penelitian ini bertujuan untuk mengetahui apakah bimbingan kelompok dengan teknik homeroom dapat meningkatkan sikap anti seks bebas peserta didik kelas IX A SMP Negeri 2 Suruh Semester genap tahun pelajaran 2019/ 2020. Jenis penelitian ini adalah penelitian tindakan bimbingan konseling (PTBK). Yang menjadi subyek dalam penelitian ini adalah delapan peserta didik laki-laki yang berasal dari kelas IX A. Teknik analisis data pada penelitian ini adalah deskriptif komparatif dimana akan dibandingkan skor rata-rata sikap anti seks bebas dan pelaksanaan layanan bimbingan kelompok dengan teknik homeroom pada setiap siklus. Kondisi awal penelitian adalah dengan rata-rata skor 16,3 dengan persentase 42% dan berada pada kategori sangat kurang. Hasil siklus 1 menunjukan terjadi peningkatan sikap anti seks bebas dari pra siklus ke siklus 1 sebesar 8,9 (54,6%), selanjutnya terdapat peningkatan lagi dari siklus 1 ke siklus 2 yaitu sebesar 7,3 atau dengan persentase sebesar 28,9%. Pada layanan bimbingan kelompok terjadi perbaikan ditunjukan dengan hasil di siklus 1 dengan rata-rata 63,7 (63,7%) meningkat di siklus 2 menjadi 86,3 (86,3%) atau bisa dikatakan terjadi peningkatan rata rata dalam layanan bimbingan kelompok sebesar 22,6 dengan persentase 35,5 %.
PENGEMBANGAN BAHAN AJAR TEMATIK BERBASIS KEARIFAN LOKAL PATI TEMA “DAERAH TEMPAT TINGGALKU” PADA SISWA KELAS IV SEKOLAH DASAR
Authors: Asmorowati Dewinta , Utomo Slamet , Surachmi Sri 
Published: May 2022

The purpose of this study 1) To find the need for thematic teaching materials based on Pati local wisdom with the theme of “Daerah tempat Tinggalku” in grade IV elementary school students, 2) to produce prototypes of thematic teaching materials based on Pati local wisdom and 3) to describe the appropriateness of thematic teaching materials based on Pati local wisdom with theme “ Daerah Tempat Tinggalku”. The research method used by Research Development with 7 stages of research includes potential and problems, data collection, design, validation, revision, testing, and revision of the final product. The result of research based on interviews and observations is the need for a companion book that is suitable for student development and based on Pati's local wisdom. The prototype of this book contains an introduction, contents based on Pati local wisdom, and a closing. The results of the validation by content experts were 23.3 or 78% and the design experts scored 28.2 or 81%. 84% of teachers agree that the use of teaching materials and student learning outcomes increases. Based on these data, it can be concluded that the thematic teaching materials based on Pati local wisdom on the theme “Daerah tempat Tinggalku” are very suitable to be used as a companion book for students from the Government in grade IV of Elementary School.
Characteristics of Fungus-Tolerant Grapevine Cultivar ‘Morava’ Grown Under Organic and Conventional Management
Authors: Ivanišević Dragoslav , Kalajdžić Mladen , Cindrić Petar , Korać Nada , Božović Predrag 
Published: May 2022

Summary
The Serbian fungus-tolerant grapevine cultivar ‘Morava’ has been recognized by both wine producers and consumers, resulting in increased areas devoted to the cultivar. ‘Morava’ (‘SK 77-7/4’ x ‘Bianca’, released in Sremski Karlovci) is a popular cultivar for white wines, particularly in the central part of Serbia, because of the interesting aroma profile of its wine. The objective of this research was to investigate the yield, grape quality and wine sensory characteristics of the ‘Morava’ grapevine cultivar grown under organic and conventional management. The experiment was conducted at an experimental field for viticulture in Sremski Karlovci (Faculty of Agriculture, University of Novi Sad) during the period 2015-2018. The grape yields produced under organic management were found lower than those under conventional management. The chemical composition of organic grapes was on par with that of conventional grapes, whereas the wine sensory characteristics of organic grapes were scored higher than those of conventional grapes.
Estimation of Nutritive Value and Protein Degradability of Trifolium Repens and Poa Pratensis as the Dominant Pasture Species, Under Simulated Rotational Grazing
Authors: Stojanović Bojan , Simić Aleksandar , Đorđević Nenad , Božičković Aleksa , Davidović Vesna , Ivetić Aleksandra 
Published: May 2022

Summary
A cutting trial was conducted to determine the nutritional value, crude protein (CP) fractions distribution and CP ruminal degradability of white clover (Trifolium repens L.) and Kentucky bluegrass (Poa pratensis L.) as the dominant species of permanent grassland. The legume and grass herbage was obtained in the field experiment carried out on pasture throughout a spring growth season where rotational grazing was simulated using three consecutive cuts, which were compared. The fractionation of CP, according to Cornell Net Carbohydrate and Protein System (CNCPS v6.5), was used to predict protein degradability of the legume and grass forage. A significant (p <0.05) lowering of the CP content in the legume and grass herbage was found, while NDF (neutral detergent fiber) and ADF (acid detergent fiber) significantly increased (p <0.05) as the spring growth season progressed. A significant decrease (p <0.05) of fractions A1 and A2 was noted in the legume and grass herbage, with a significant (p <0.05) increase of CP fractions B2 and C as the vegetation season progressed. A higher rumen degradable protein (RDP) content (p <0.05) of white clover and Kentucky bluegrass herbage was obtained in the first harvest, compared with the second and third one. Significantly larger values (p <0.05) of net energy were observed in the white clover and Kentucky bluegrass forage obtained from the first cut, compared with later regrowths, and white clover was characterized by a higher energy content of 12.4–33.1% (dry matter basis), relative to Kentucky bluegrass.
Knowledge, Attitude and Practice Analysis of Inclusive Extension Service Among Agricultural Extension Workers in Southwestern Nigeria
Authors: Adeloye Kolawole Adelekan , Torimiro Dixon Olutade , Omoboyede Deborah Anu , Arowolo Bisola Deborah , Adedipe Ifeoluwa Ezra , Alao Adebukola Nafisat 
Published: May 2022

Summary
The study analysed the knowledge, attitude and practice (KAP) of inclusive extension service among agricultural extension workers in southwestern Nigeria. All the extension workers (268) in Agricultural Development Programmes (ADPs) in five states randomly selected within southwestern Nigeria were interviewed for the study via a structured and pre-tested questionnaire. The collected data were presented using descriptive and inferential statistics. The mean age, formal education and job experience of the extension workers were 43.3±8.4, 17.0±2.6 and 14.1±8.4 years, respectively. The majority of the respondents were male (74.3%) and married (77.8%). Furthermore, most of them have encountered farmers with special needs such as albinism (81.7%), hearing impairment (87.3%), visual impairment (85.2%) and mental disability (81.7%) among others. The majority of the respondents (60.0%) had high capacity for inclusive extension service. The extension workers differed significantly across the states in terms of their practice scores, but not in their knowledge and attitude scores. The findings revealed that at p<0.05, job experience (r= 0.483) and age (r=0.322) of the respondents had significant relationship with KAP of inclusive extension service. Therefore, the hypothesis was accepted for sex and marital status, but was rejected for ethnicity, age and job experience. The study concludes that the extension workers differ significantly across the states in terms of practices, but not in their knowledge and attitude about inclusive extension services.
A Goal Programming Approach to Multi-Objective Farm Planning Among Small-Scale Arable Crop Farmers in Kogi State, Nigeria
Authors: Okpanachi Francis Okoliko , Tanko Likita , Ibrahim Faith Debaniyu , Adewumi Adeoluwa 
Published: May 2022

Summary
The purpose of this study was to develop prototype farm plans according to the multi-objective production goals of small-scale arable crop producers in Kogi State, Nigeria. A multi-stage sampling technique was used to select a total of 137 farm households in different local government areas (LGAs). A structured questionnaire complemented with interview schedule was used to collect primary data from the respondents. Descriptive statistics and linear goal programming were used for data analysis. The results obtained indicate that the optimal plan of generating an income of ₦242,076.20 requires 0.368 ha of melons, 0.044 ha of yam/maize mixture and 0.259 ha of sorghum/groundnuts. The optimal net profit was 44.05% higher than that achieved by implementing the existing plan. To meet family food requirements, the solution plan prescribed devoting 0.048 ha to cassava, 0.211 ha to sorghum, 0.368 ha to melons, 0.074ha to Bambara nuts, and 1.065 ha to sorghum/groundnuts to generate an income of ₦158,475.00. To minimize paid labour and generate an income of ₦168,325.50, the plan prescribed devoting 0.195 ha to rice, 0.502 ha to melons and 0.246 ha to Bambara nuts. Out of the three basic farm household objectives considered, meeting family food requirements and limiting labour expenditure were overachieved, whereas the objective of maximizing farm income was underachieved. A great deal of the existing staple food plan was found consistent with the prescribed optimal plan, except in the case of existing cassava and Bambara nut production which was falling short of the optimal production prescribed. The maize/groundnut production had the lowest shadow prices. However, land, labour, capital, agrochemicals, fertilizers and seeds constituted the limiting resources in the plan. It was found that these resources were not optimally allocated in the existing plan for arable crop activities. Therefore, the respondents were advised to utilize their resources as prescribed in the optimum plan, supported by farm advisory services in selecting good crop mixtures.