bluuebunny/crossref_metadata_2025_split huggingface dataset:
Agribusiness potential of castor oil plant (Ricinus communis L.) in Mexico
Authors: VASCO LEAL JOSE FERNANDO , Cuellar-Nuñez Liceth , Vivanco-Vargas Martín , Solís-Lozano Juan A. , Díaz-Calzada María E. , Méndez-Gallegos S.de J. 
Published: June 2022

Objective: To describe the agribusiness potential of the castor oil plant in Mexico through the collection and analysis of agricultural, industrial and commercial information that allows decision making for the formulation of future productive projects to generate economic, social and technological impacts.Design/Methodology/Approach: The study is descriptive with a transactional design. The information was collected on national and international agrifood statistical and documentary information platforms.Results: Different attempts have been made in Mexico in commercial and research projects related to the cultivation, production and transformation of castor oil, with results that are not very encouraging due to the lack of knowledge about productive, technological and commercial processes. However, on the other hand, the need for the industrial sector to import oil to produce high-value products is evident.
Study Limitations/Implications: Isolated efforts have been made by each of the actors in the castor oil agribusiness, which has prevented the sector’s consolidation.Findings/Conclusions: An intelligent management of agricultural production must be implemented through the establishment of commercial crops with the adoption of basic technological packages applied to each region in particular, with great attention to the availability of planting seed, which should have agronomic potential, use of nutrition and management of pests and diseases, as well as to foresee all the cultural tasks ofmaintenance of the crop and harvesting modality that guarantee yield in the field and quality raw material. Currently, there is a deficit in the castor oil market in the country, which leads to high business prospects and business opportunities.
PERANAN PENDIDIKAN AGAMA KRISTEN DALAM MENGEDUKASI PESERTA DIDIK TENTANG BAHAYA PENYALAHGUNAAN NARKOBA
Authors: Marsaulina Roce , Kia Dan , Tefbanna Abraham 
Published: June 2022

Kami tim penggagas kegiatan PKM ini menjalin kerjasama dengan BNN melalui GERAM sebagai motor penggerak dalam pencegahan dan pemberantasan penyalahgunaan narkoba di Indonesia. Tujuan PKM ini, untuk mengedukasi para peserta didik di SMPS Mitra di Kampung Cina – Tajurhalang – Bogor agar tahu tentang bahaya penyalahgunaan narkoba, mengenal jenis-jenis narkoba, gejala-gejala para korban penyaahgunaan narkoba agar tidak ikut terlibat, tetapi berperan serta dalam pencegahannya. Dalam merealisasi dari kegiatan mengedukasi masyarakat (peserta didik) tentang bahaya penyalahgunaan narkoba kali ini, diadakan dalam bentuk seminar kepada peserta didik. Penyalahgunaan narkotika adalah tindakan yang merusak tubuh yang adalah bait Allah, karena secara tegas firman Tuhan mengatakan bahwa tubuh kita adalah bait Allah tempat Roh Allah berdiam. Dari sinilah peran PAK dalam keluarga, gereja, sekolah dan masyarakat sangat dibutuhkan. Sehingga baik pelajar, orang tua dan pendidik memahami bahwa lebih baik mencegah atau tidak menyentuh sama sekali narkoba dari pada mengobati yang merupakan harapan dari kegiatan yang dilaksanakan.
PENGARUH PUPUK PELENGKAP CAIR, PUPUK UREA DAN NPK TERHADAP PERTUMBUHAN DAN HASIL TANAMAN PADI (Oryza sativa L.) VARIETAS CIHERANG
Authors: Tadjudin E , Alfandi - , Yafenka Diah Ekawati Sulihalialevi 
Published: June 2022

This study aims to determine: (1) the effect of Complementary Liquid Fertilizer, Urea and NPK on the growth and yield of rice (Oryza sativa L.) Ciherang varieties, (2) the influence of Complementary Liquid Fertilizer, Urea and NPK the most good for growth and yield of rice (Oryza sativa L.) Ciherang varieties, and (3) the correlation between the components of the growth and yield of rice (Oryza sativa L.) Ciherang varieties. The experiment was conducted Kecomberan Villages Talun District Cirebon Regency, from May through the month of August 2015. The method used in this study is the experimental method. The experimental design used a randomized block design (RBD), factorial. The study consisted of two treatment factors were repeated 3 times. The first factor, concentration of complementary liquid fetilizer consists of three levels, namely: K1 (1 cc/Liter per plot), K2 (2 cc/Liter per plot), and K3 (3 cc/Liter per plot). The second factor is dose fertilizer (P) consists of three levels, namely: P1 (Urea 200 kg/ha, NPK 150 kg/ha), P2 (Urea 250 kg/ha, NPK 200 kg/ha), and P3 (Urea 300 kg/ha, NPK 250 kg/ha).
Análise de uma maior autonomia do Banco Central na condução da política monetária do Brasil
Authors: Júnior Armando Pereira Costa , Cordeiro Luciana Maria Costa , Rezende Luiz Paulo Fontes de , Fialho Tânia Marta Maia 
Published: June 2022

Resumo:
O objetivo deste artigo é analisar os efeitos de uma maior autonomia operacional do Banco Central do Brasil na condução da política monetária após a adoção do regime de metas de inflação em1999. Além da discussão teórica sobre autonomia do Banco Central, estimou-se um modelo da regra de Taylor no período de julho de 1994 a abril de 2015. Conclui-se que o regime de metas é instrumento eficiente para dar maior autonomia ao Banco Central na condução da política monetária. Os resultados obtidos pela regra de Taylor foram favoráveis ao crescimento e à estabilidade da economia brasileira no período analisado.
Situações-limite e o espetáculo – o hiperespetáculo pelo viés da construção das identidades
Authors: Reis Pedro Henrique Baptista 
Published: June 2022

Neste artigo pretendemos aproximar e articular os conceitos de espetáculo, de Guy Debord, e de situação-limite, de Karl Jaspers, afim de transpor certas aporias com os quais o pensamento debordiano se enfrenta, confronta e transforma numa época que se desenha como tecnocrática e na qual os meios de comunicação e informações tornam-se ubíquos e os sujeitos, mediados e mediadores, se veem transformados por uma vivência na presença e através desses meios.
A história oral como disciplina, a memória coletiva e a “costura artesanal” – religião, política
Authors: Alonso Leandro Seawright 
Published: June 2022

Procurei demonstrar que a história oral se desenvolveu no âmbito de uma disciplinaridade; utilizei-me de excertos da literatura machadiana para demonstrar a importância das entrevistas; apresentei o conceito de “costura artesanal”. Posteriormente, utilizei-me do conceito de memória coletiva e de história oral testemunhal para demonstrar ser possível trabalhar com trauma, política e religião.
Biodiesel from Dodonaea Plant Oil: Synthesis and Characterization—A Promising Nonedible Oil Source for Bioenergy Industry
Authors: Bukhari Syeda Alia Zehra , Ullah Kifayat , Ahmad Mushtaq , Zafar Muhammad , Ullah Anwar , Sultana Shazia , Ibrahim Mohamed Mousa , Hessien Mahmoud Mohamed , Mersal Gaber Ahmad Mahmoud , Ghoneim Sherif Salama Mohamed 
Published: June 2022

In this work, Dodonaea oil was studied as a potential biodiesel source. Dodonaea (Dodonaea viscosa Jacq.) is an evergreen shrubby plant that thrives in tropical and subtropical conditions. The plant produces high-grade biodiesel in terms of both quantity and quality despite its naturally high fat content. In the transesterification followed by esterification reaction, varied ratios of oil to methanol, constant temperature (60°), reaction duration (1 h), and different catalyst concentrations (0.25–0.75% (w/w) were utilized. A maximum biodiesel yield of 90% was achieved. For fuel characteristic analysis, the prepared biodiesel was specified and compared to ASTM criteria. The chemical composition was verified using analytical techniques such as FT-IR and NMR spectroscopy. As a result of the foregoing, Dodonaea is considered a possible bioenergy source, particularly in the transport sector.
Effect of the Innovative Running Shoes With the Special Midsole Structure on the Female Runners’ Lower Limb Biomechanics
Authors: Fu Fengqin , Guo Lianming , Tang Xunfei , Wang Jiayu , Xie Zhihao , Fekete Gusztáv , Cai Yuhui , Hu Qiuli , Gu Yaodong 
Published: June 2022

The study aimed to research the effects of innovative running shoes (a high heel-to-toe drop and special structure of midsole) on the biomechanics of the lower limbs and perceptual sensitivity in female runners. Fifteen healthy female runners were recruited to run through a 145-m runway with planted force plates at one peculiar speed (3.6 m/s ± 5%) with two kinds of shoe conditions (innovative running shoes vs. normal running shoes) while getting biomechanical data. The perception of shoe characteristics was assessed simultaneously through a 15-cm visual analog scale. The statistical parametric mapping technique calculated the time-series parameters. Regarding 0D parameters, the ankle dorsiflexion angle of innovative running shoes at touchdown was higher, and the peak dorsiflexion angle, range of motion, peak dorsiflexion velocity, and plantarflexion moment on the metatarsophalangeal joint of innovative running shoes during running were significantly smaller than those of normal running shoes (all p &lt; 0.001). In addition, the braking phase and the time of peak vertical force 1 of innovative running shoes were found to be longer than those of normal running shoes (both p &lt; 0.05). Meanwhile, the average vertical loading rate 1, peak vertical loading rate 1, peak braking force, and peak vertical force 1 in the innovative running shoes were lower than those of the normal running shoes during running (both p &lt; 0.01). The statistical parametric mapping analysis exhibited a higher ankle dorsiflexion angle (0–4%, p &lt; 0.05), a smaller knee internal rotation angle (0–6%, p &lt; 0.05) (63–72%, p &lt; 0.05), a decreased vertical ground reaction force (11–17%, p = 0.009), and braking anteroposterior ground reaction force (22–27%, p = 0.043) for innovative running shoes than normal running shoes. Runners were able to perceive the cushioning of innovative running shoes was better than that of normal running shoes. These findings suggested combining the high offset and structure of the midsole would benefit the industrial utilization of shoe producers in light of reducing the risk of running injuries for female runners.
High Dose Intramuscular Vitamin D3 Supplementation Impacts the Gut Microbiota of Patients With Clostridioides Difficile Infection
Authors: Lee Sang Hoon , Park Han-Ki , Kang Chang Don , Choi Dae Hee , Park Sung Chul , Park Jin Myung , Nam Seung-Joo , Chae Gi Bong , Lee Kyoung yul , Cho Hyunseok , Lee Sung Joon 
Published: June 2022

Background and AimCurrent therapeutic strategies for Clostridioides difficile infections (CDI), including oral vancomycin, metronidazole and fecal microbial transplantation, have limited efficacy and treatment failure may occur in as many as one- third of cases. Recent studies have reported that lower concentrations of 25-hydroxyvitamin D are associated with CDI severity and recurrence. However, there have been no studies on microbiota composition after the administration of vitamin D in patients with CDI. Therefore, our study aimed to compare the microbiota composition between the two groups, including eight CDI-positive patients with vitamin D supplementation and ten CDI-positive patients without vitamin D supplementation by using 16S rRNA microbial profiling.MethodsTwenty subjects were enrolled in this prospective randomized controlled study. One subject dropped out due to lack of contact with the guardian after discharge and one subject dropped out due to withdrawal of consent. Thus, 18 patients with CDI and vitamin D insufficiency (vitamin D level &lt; 17 ng/mL) were divided into two groups: CDI with vitamin D supplementation (n = 8) and CDI without vitamin D supplementation (control: n = 10). Subjects with vitamin D insufficiency were randomized to receive 200,000 IU intramuscular cholecalciferol whereas patients in the control group received only oral vancomycin. Stool samples were obtained twice before vancomycin was administered and eight weeks after treatment; the V3-V4 16S rRNA metagenomic sequencing was performed using EzBioCloud.ResultsThe alpha diversity of the gut microbiota in the recovery state was significantly higher than that in the CDI state. Analysis of bacterial relative abundance showed significantly lower Proteobacteria and higher Lachnospiraceae, Ruminococcaceae, Akkermansiaceae, and Bifidobacteriaceae in the recovery state. When comparing the control and vitamin D treatment groups after eight weeks, increase in alpha diversity and, abundance of Lachnospiraceae, and Ruminococcaceae exhibited the same trend in both groups. A significant increase in Bifidobacteriaceae and Christensenellaceae was observed in the vitamin D group; Proteobacteria abundance was significantly lower in the vitamin D treatment group after eight weeks than that in the control group.ConclusionOur study confirmed that the increase in the abundance of beneficial bacteria such as Bifidobacteriaceae, and Christensenellaceae were prominently evident during recovery after administration of a high dose of cholecalciferol. These findings indicate that vitamin D administration may be useful in patients with CDI, and further studies with larger sample sizes are required.
Angiographic Lesion Morphology Provides Incremental Value to Generalize Quantitative Flow Ratio for Predicting Myocardial Ischemia
Authors: Zhang Jie , Zhao Na , Xu Bo , Xie Lihua , Yin Weihua , An Yunqiang , Yan Hankun , Yu Yitong , Lu Bin 
Published: June 2022

AimThe quantitative flow ratio (QFR) is favorable for functional assessment of coronary artery stenosis without pressure wires and induction of hyperemia. The aim of this study was to explore whether angiographic lesion morphology provides incremental value to generalize QFR for predicting myocardial ischemia in unselected patients.MethodsThis study was a substudy to the CT-FFR CHINA trial, referring 345 participants from five centers with suspected coronary artery disease on coronary CT angiography for diagnostic invasive coronary angiography (ICA). Fractional flow reserve (FFR) was measured in all vessels with 30–90% diameter stenosis. QFR was calculated in 186 lesions from 159 participants in a blinded manner. In addition, parameters to characterize lesion features were recorded or measured, including left anterior descending arteries (LADs)-involved lesions, side branch located at stenotic lesion (BL), multiple lesions (ML), minimal lumen diameter (MLD), reference lumen diameter (RLD), percent diameter stenosis (%DS), lesion length (LL), and LL/MLD4. Logistic regression was used to construct two kinds of models by combining single or two lesion parameters with the QFR. The performances of these models were compared with that of QFR on a per-vessel level.ResultsA total of 148 participants (mean age: 59.5 years; 101 men) with 175 coronary arteries were included for final analysis. In total, 81 (46%) vessels were considered hemodynamically significant. QFR correctly classified 82.29% of the vessels using FFR with a cutoff of 0.80 as reference standard. The area under the receiver operating characteristic curve (AUC) of QFR was 0.86 with a sensitivity, specificity, positive predictive value, and negative predictive value of 80.25, 84.04, 81.25, and 83.16%, respectively. The combined models (QFR + LAD + MLD, QFR + LAD + %DS, QFR + BL + MLD, and QFR + BL + %DS) outperformed QFR with higher AUCs (0.91 vs. 0.86, P = 0.02; 0.91 vs. 0.86, P = 0.02; 0.91 vs. 0.86, P = 0.02; 0.90 vs. 0.86, P = 0.03, respectively). Compared with QFR, the sensitivity of the combined models (QFR + BL and QFR + MLD) was improved (91.36 vs. 80.25%, 91.36 vs. 80.25%, respectively, both P &lt; 0.05) without compromised specificity or accuracy.ConclusionCombined with angiographic lesion parameters, QFR can be optimized for predicting myocardial ischemia in unselected patients.
Riverbed Temperature and 4D ERT Monitoring Reveals Heterogenous Horizontal and Vertical Groundwater-Surface Water Exchange Flows Under Dynamic Stage Conditions
Authors: Johnson Tim , Thomle Jon , Stickland Chris , Goldman Amy , Stegen James 
Published: June 2022

Groundwater surface water exchange plays a critical role in physical, biological, and geochemical function of coastal and riverine systems. Observing exchange flow behavior in heterogeneous systems is a primary challenge, particularly when flows are governed by dynamic river stage or tidal variations. In this paper we demonstrate a novel application of time-lapse 3D electrical resistivity tomography and temperature monitoring where an array of thermistors installed beneath a riverbed double as resistivity electrodes. We use the array to monitor stage driven exchange flows over a 6-day period in a dynamic, stage-driven high order stream. We present a method for addressing the otherwise confounding effects of the moving river-surface boundary on the raw resistivity data, thereby enabling successful tomographic imaging. Temperature time-series at each thermistor location and time-lapse 3D images of changes in bulk electrical conductivity together provide a detailed description of exchange dynamics over a 10-meter by 45-meter section of the riverbed, to a depth of approximately 5 m. Results reveal highly variable flux behavior throughout the monitoring domain including both horizontal and vertical exchange flows.
The rs10830963 Polymorphism of the MTNR1B Gene: Association With Abnormal Glucose, Insulin and C-peptide Kinetics
Authors: Vejrazkova Daniela , Vankova Marketa , Vcelak Josef , Krejci Hana , Anderlova Katerina , Tura Andrea , Pacini Giovanni , Sumova Alena , Sladek Martin , Bendlova Bela 
Published: June 2022

BackgroundThe MTNR1B gene encodes a receptor for melatonin, a hormone regulating biorhythms. Disruptions in biorhythms contribute to the development of type 2 diabetes mellitus (T2DM). Genetic studies suggest that variability in the MTNR1B gene affects T2DM development. Our aim was to compare the distribution of the genetic variant rs10830963 between persons differing in glucose tolerance in a sample of the Czech population (N=1206). We also evaluated possible associations of the polymorphism with insulin sensitivity, beta cell function, with the shape of glucose, insulin and C-peptide trajectories measured 7 times during a 3-hour oral glucose tolerance test (OGTT) and with glucagon response. In a subgroup of 268 volunteers we also evaluated sleep patterns and biorhythm.Results13 persons were diagnosed with T2DM, 119 had impaired fasting blood glucose (IFG) and/or impaired glucose tolerance (IGT). 1074 participants showed normal results and formed a control group. A higher frequency of minor allele G was found in the IFG/IGT group in comparison with controls. The GG constellation was present in 23% of diabetics, in 17% of IFG/IGT probands and in 11% of controls. Compared to CC and CG genotypes, GG homozygotes showed higher stimulated glycemia levels during the OGTT. Homozygous as well as heterozygous carriers of the G allele showed lower very early phase of insulin and C-peptide secretion with unchanged insulin sensitivity. These differences remained significant after excluding diabetics and the IFG/IGT group from the analysis. No associations of the genotype with the shape of OGTT-based trajectories, with glucagon or with chronobiological patterns were observed. However, the shape of the trajectories differed significantly between men and women.ConclusionIn a representative sample of the Czech population, the G allele of the rs10830963 polymorphism is associated with impaired early phase of beta cell function, and this is evident even in healthy individuals.
RETRACTED: Globally, Freshwater Ecosystems Emit More CO2 Than the Burning of Fossil Fuels
Authors: Pollard Peter C. 
Published: June 2022

Freshwater emits substantial volumes of CO2 to the atmosphere. This has largely gone unnoticed in global carbon budgets. My aim was to quantify the CO2 emanating from freshwater from 66° N to 47° S latitudes via in situ bacterial respiration (BR). I determined BR (n = 326) as a function of water temperature. Freshwater is emitting CO2 at a rate of 58.5 Pg C y−1 (six times that of fossil fuel burning). Most is emitted from the Northern Hemisphere. This is because the high northern summer temperatures coincide with most of the world’s freshwater. Diffuse DOC sources, for example dust, may be driving high freshwater BR. However, many sources remain elusive and not individually quantified in the literature. We must include freshwater CO2 emissions in climate models. Identifying, quantifying and managing freshwater’s diffuse sources of Dissolved Organic Carbon (DOC) will hopefully provide us with another opportunity to change our current climate trajectory.
Identification of the Immune Subtype of Hepatocellular Carcinoma for the Prediction of Disease-Free Survival Time and Prevention of Recurrence by Integrated Analysis of Bulk- and Single-Cell RNA Sequencing Data
Authors: Fu Jie , Lei Xiaohua 
Published: June 2022

BackgroundThe main factors affecting the long-term prognosis of hepatocellular carcinoma (HCC) patients undergoing radical surgery are recurrence and metastasis. However, the methods for predicting disease-free survival (DFS) time and preventing postoperative recurrence of HCC are still very limited.MethodsIn this study, immune cell abundances in HCC samples were analyzed by single-sample gene set enrichment analysis (ssGSEA), while the prognostic values of immune cells for DFS time prediction were evaluated by the least absolute shrinkage and selection operator (LASSO) and subsequent univariate and multivariate Cox analyses. Next, a risk score was constructed based on the most prognostic immune cells and their corresponding coefficients. Interactions among prognostic immune cells and the specific targets for the prevention of recurrence were further identified by single-cell RNA (scRNA) sequencing data and CellMiner.ResultsA novel efficient T cell risk score (TCRS) was constructed based on data from the three most prognostic immune cell types (effector memory CD8 T cells, regulatory T cells and follicular helper T cells) for identifying an immune subtype of HCC patients with longer DFS times and inflammatory immune characteristics. Functional differences between the high- and low-score groups separated by TCRS were clarified, and the cell-cell communication among these immune cells was elucidated. Finally, fifteen hub genes that may be potential therapeutic targets for the prevention of recurrence were identified.ConclusionsWe constructed and verified a useful model for the prediction of DFS time of HCC after surgery. In addition, fifteen hub genes were identified as candidates for the prevention of recurrence, and a preliminarily investigation of potential drugs targeting these hub genes was carried out.