bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pasos Hacia La Salud II: study protocol for a randomized controlled trial of a theory- and technology-enhanced physical activity intervention for Latina women, compared to the original intervention
Authors: Mendoza-Vasconez Andrea S. , Benitez Tanya , Dunsiger Shira , Gans Kim M. , Hartman Sheri J. , Linke Sarah E. , Larsen Britta A. , Pekmezi Dorothy , Marcus Bess H. 
Published: August 2022

Abstract
Background
Latinas are at increased risk for many lifestyle-related chronic diseases and are one of the least physically active populations in the US Innovative strategies are needed to help Latinas achieve the health benefits associated with physical activity (PA). This manuscript describes the study protocol of the Pasos Hacia La Salud II Study, which builds upon our previous research to test an enhanced individually-tailored, text-message and website-delivered, Spanish-language intervention (enhanced intervention), in comparison to the original web-based Pasos Hacia La Salud Intervention (original intervention).

Methods
Sedentary Latinas between the ages of 18–65 will be recruited and will complete an orientation and baseline assessments. Participants will be subsequently randomized to the original intervention, or the Enhanced Intervention, which has greater targeting of theoretical constructs such as self-efficacy, enjoyment, and social support, and which uses text messages and more dynamic and refined website features to encourage increased website use. Using a linear mixed effects regression model, we will simultaneously estimate the intervention effects on mean accelerometer-measured hours/week of moderate-to-vigorous PA (MVPA) at 6, 12, 18, and 24 months, with a subject-specific intercept (intent-to-treat sample). Change in self-reported MVPA, measured via the 7-day Physical Activity Recall, will be assessed as a secondary outcome using a similar model. We will investigate potential mediators of the intervention effect using a multiple mediation approach, and potential moderators by evaluating potential interactions. As an exploratory outcome, we will study the differences (among both study arms) in cost, in US dollars, per minute increases in weekly mean MVPA.

Discussion
The original Pasos PA intervention showed efficacy in helping Latinas increase PA; we expect the Enhanced Intervention to help a larger proportion of participants to increase and maintain their PA long term. This web- and text-based enhanced intervention could have great reach and dissemination potential, which could be capitalized on in the future to help to advance health equity. Adaptations made in response to the COVID-19 pandemic are also described in this manuscript.

Trial registration
Clinical Trial Number: NCT03491592. First posted April 9, 2018.
Clear cell sarcoma of the kidney with inferior vena cava thrombus: a case report
Authors: Doya Leen Jamel , Alyousef Khaled , Oukan Majdy , Razzok Ali , Alshabab Basel Shek , AlEid Tarek , Saloum Rabab , Nasser Hassan 
Published: August 2022

Abstract
Background
Clear cell sarcoma of the kidney is an uncommon pediatric renal malignant neoplasm that is typically characterized in 2–3-year-olds by aggressive behavior and late relapses. Our literature review revealed fewer than ten previously reported cases of CCSK with inferior vena cava thrombus, with only five in the pediatric age group.

Case presentation
We report the case of a 14-year-old Syrian girl who complained of mild pain in the left lumbar region pain with hematuria. On physical examination, a mass was palpated in the left flank. Abdominal ultrasonography revealed a left renal mass (7 × 5 × 2 cm3), associated with dilatation of the left renal vein. Contrast abdominal computed tomography showed a mass measuring 7 × 5 × 3 cm3 with the presence of thrombus extending into the inferior cavity down to the right atrium that was initially diagnosed as Wilms’ tumor. Radical right nephrectomy with excision of the thrombus was undertaken. Histological immunostaining revealed a diagnosis of the tumor as clear cell sarcoma with vascular tumor thrombus extending to the inferior vena cava.

Conclusion
Clear cell sarcoma and Wilms’ tumor are similar in terms of typical age of appearance, clinical features, and histopathology, but with different methods of treatment and prognosis. The differential diagnosis of such masses is thus very important. We present the case of a patient with clear cell sarcoma with unusual age, with complete removal of the thromboses in the inferior vena cava and the right atrium.
Floristic composition, growth temperament and conservation status of woody plant species in the Cameroonian tropical rainforests
Authors: Kengne Olivier Clovis , Feukeng Samuel Severin Kenfack , Ngansop Eric Tchatchouang , Meyan-ya Raissa Gwladys Daghela , Zapfack Louis 
Published: August 2022

Abstract
Introduction
Cameroon’s tropical rainforests are nowadays strewn with rural forests maintained by local populations; however, these forests are not officially recognized in the non-permanent forest domain. Rural forests are non-delimited riparian areas within the dense moist forest, reserved for rural housing, agricultural activities and agroforestry practices, freely exploited by the local communities for their livelihood without them having any rights to artisanal and commercial logging. This study aimed at contributing to the flora knowledge and the conservation state of woody plant species in rainforests. The study was carried out in two rural forests located in the Eastern and Southern agroforestry zones of Cameroon.

Methods
The method adopted for floristic inventories combined a fixed area sampling unit and a variable area sampling unit. Woody individuals with diameter at breast height (dbh) < 3.2 cm were counted and shrubs of 3.2 ≤ dbh < 10 cm were measured to analyse the understorey, while trees with dbh ≥ 10 cm were measured and identified to characterize the canopy.

Results
In the Essiengbot-Mbankoho rural forest in Eastern Cameroon, 468 species belonging to 61 families were recorded in the understory while 227 species belonging to 53 families were identified at the canopy level. A total of 40 (7.68%) threatened species, 18 (3.45%) Near Threatened species and 408 (78.31%) Least Concern species were recorded. In the Nbgwassa-Opkweng rural forest in Southern Cameroon, 534 species belonging to 64 families were identified in the understory while 225 species belonging to 43 families were recorded in the canopy. A total of 54 (9.69%) threatened species, 25 (4.49%) Near Threatened species and 421 (75.58%) Least Concern species were identified in this forest. Shannon’s diversity indices were above five in the understories and canopies of both forests. Shade-bearer species were the most represented in the understories while the non-pioneer light-demanding and shade-bearer species were the most abundant in the canopies.

Conclusions
Despite the influence of slash-and-burn agriculture and subsistence farming practices, rural forests managed by local populations provide opportunities for preserving plant biodiversity. However, the presence of threatened species, pioneer species and non-pioneer light-demanding species in these forests is an indicator of moderate and man-induced disturbances that, in the absence of a forest management plan or sustainable management, may threaten this biodiversity. Legal management of rural forests could help in limiting the anthropogenic activities and pressures on community forests.
Flexural Behavior of Low Calcium Fly Ash Based Geopolymer Reinforced Concrete Beam
Authors: Alex Alexander Gladwin , Gebrehiwet Tewele Tsegay , Kemal Zeyneb , Subramanian Ramesh Babu 
Published: August 2022

AbstractPioneering studies have been conducted on alternative cementitious material in the manufacturing of conventional concrete to reduce carbon emission and improve the overall efficacy. However, there are limited studies on eco-friendly materials with low calcium fly ash. This study aims to examine the strength fly ash geopolymer concrete and reduce carbon emission. In this investigation, flexural test is done for conventional and geopolymer concrete (GPC) beam samples after the fulfillment of rest period and 24 h steam curing at 60 °C. The experimental results prove that the initial characteristics of both specimens are almost similar. When GPC specimens reached the service, yield, and failure stages, the load carrying capacity, deflection increased up to 21.5 and 8.75%, respectively and better load bearing capacity, moment resistance, and crack propagation were observed more than in conventional cement. Fresh property test results indicated the achievement of standard workability without the addition of any admixture. Our study show that low calcium based geopolymer can be used as an efficient material for the alternate of cement in cement-based industries with eco-friendly nature.
The role of sense of coherence and loneliness in borderline personality disorder traits: a longitudinal twin study
Authors: Skaug Eirunn , Czajkowski Nikolai O. , Waaktaar Trine , Torgersen Svenn 
Published: August 2022

Abstract
Background
Borderline personality disorder (BPD) implies having problems with identity and relations with other people. However, not much is known about whether these indications of BPD are present in adolescence, i.e., before personality disorders usually are diagnosed. In this study, we examined the prediction of an aspect of identity (i.e., sense of coherence [SOC]) and social relations (i.e., perceived loneliness) throughout adolescence on BPD traits in young adulthood. In addition, we examined to what degree the predictive ability could be attributed to genetic and environmental factors. We also examined whether life events in adolescence were related to BPD traits.

Methods
Three thousand three hundred ninety-one twins, consisting of seven national birth cohorts from Norway, participated in the study. SOC, loneliness and life events were measured three times throughout adolescence with self-report questionnaires, with 2 years in between measurements. BPD traits were measured at the end of adolescence around the age of 19 with a structured interview. Regression analyses were performed to examine the prediction of SOC, loneliness and life events on BPD traits. Cholesky decomposition models were then used to determine to what degree the associations were due to genetic and environmental influences.

Results
The prediction of SOC and loneliness on BPD traits increased from R = .25 (when measured 6 years prior to the assessment of BPD traits) to R = .45 (when measured shortly before the assessment of BPD traits). In addition, negative life events considered dependent on a person’s behavior were related to BPD traits. Negative independent and positive dependent life events did not contribute to the prediction of BPD traits. Cholesky decomposition models showed that SOC and loneliness were associated with BPD traits mainly due to shared genetic influences (i.e., the proportion due to genetic influences ranged from 71 to 86%). Adding negative dependent life events to the prediction of BPD traits did not change these percentages.

Conclusions
These findings indicate that the weaker SOC, the stronger feelings of loneliness, and the negative life events associated with BPD traits are mainly consequences of the genetic aspects of BPD traits, rather than having direct effects on levels of BPD symptoms.
Torque movement of the upper anterior teeth using a clear aligner in cases of extraction: a finite element study
Authors: Cheng Yuxun , Gao Jie , Fang Shishu , Wang Wei , Ma Yanning , Jin Zuolin 
Published: August 2022

Abstract
Background
Clear aligner treatment has become popular over recent years. It is necessary to identify methods by which we could avoid the bowing effect in extractions with clear aligner. The present study was to identify the appropriate method to design torque movement involving the upper anterior teeth of extraction cases, in order to maintain or improve the axis and torque of the upper anterior teeth with a clear aligner during movement and closure of the extraction space.

Results
As the height of the power ridge increased, the rotation angle of the upper central incisor in the sagittal direction decreased gradually and the location of the rotation center changed significantly; the rotation center moved in the apical direction and then changed to the crown side. The highest von-Mises stress of the upper central incisor root, periodontal ligaments, and alveolar bone, showed little change as the power ridge height increased. When the axial inclination of the upper central incisor was normal (U1-SN = 105°), the tendency of movement for the upper central incisor approached translation with a power ridge height of 0.7 mm (corresponding distorted angle: 5.8415). When the axial inclination of the upper central incisor was oversized (U1-SN = 110°), the axial inclination of the upper central incisor reduced to normal following completion of the anterior segment retraction with a power ridge of 0.4 mm (corresponding distorted angle: 3.4265).

Conclusion
Analysis indicates that pure palatal tipping movement of the upper anterior teeth is generated without torque control, thus resulting in the bowing effect. The required torque control of the upper anterior teeth with oversize axial inclination is weaker than that of the upper anterior teeth with normal axial inclination because limited torque loss is expected for oversize axial inclination teeth. Variation sensitivity of the rotation center should be considered carefully due to biological problems when designing translation of the upper anterior teeth with normal axial inclination.
Correcting magnification error in foveal avascular zone area measurements of optical coherence tomography angiography images with estimated axial length
Authors: Dutt Deepaysh D. C. S. , Yazar Seyhan , Charng Jason , Mackey David A. , Chen Fred K. , Sampson Danuta M. 
Published: August 2022

Abstract
Background
To generate and validate a method to estimate axial length estimated (ALest) from spherical equivalent (SE) and corneal curvature [keratometry (K)], and to determine if this ALest can replace actual axial length (ALact) for correcting transverse magnification error in optical coherence tomography angiography (OCTA) images using the Littmann-Bennett formula.

Methods
Data from 1301 participants of the Raine Study Gen2-20 year follow-up were divided into two datasets to generate (n = 650) and validate (n = 651) a relationship between AL, SE, and K. The developed formula was then applied to a separate dataset of 46 participants with AL, SE, and K measurements and OCTA images to estimate and compare the performance of ALest against ALact in correcting transverse magnification error in OCTA images when measuring the foveal avascular zone area (FAZA).

Results
The formula for ALest yielded the equation: ALest = 2.102K − 0.4125SE + 7.268, R2 = 0.794. There was good agreement between ALest and ALact for both study cohorts. The mean difference [standard deviation (SD)] between FAZA corrected with ALest and ALact was 0.002 (0.015) mm2 with the 95% limits of agreement (LoA) of − 0.027 to 0.031 mm2. In comparison, mean difference (SD) between FAZA uncorrected and corrected with ALact was − 0.005 (0.030) mm2, with 95% LoA of − 0.064 to 0.054 mm2.

Conclusions
ALact is more accurate than ALest and hence should be used preferentially in magnification error correction in the clinical setting. FAZA corrected with ALest is comparable to FAZA corrected with ALact, while FAZA measurements using images corrected with ALest have a greater accuracy than measurements on uncorrected images. Hence, in the absence of ALact, clinicians should use ALest to correct for magnification error as this provides for more accurate measurements of fundus parameters than uncorrected images.
Survival analysis of myopic regression after small incision lenticule extraction and femtosecond laser-assisted laser in situ keratomileusis for low to moderate myopia
Authors: Zhou Jihong , Gu Wei , Gao Yan , Wang Wenjuan , Zhang Fengju 
Published: August 2022

Abstract
Background
To report the predictive factors of myopic regression in patients who had undergone small incision lenticular extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileuses (FS-LASIK) after 3–12 months of follow-up.

Methods
This retrospective case series study recruited patients with a subjective sphere of − 1.00 to − 6.00 D myopia. SMILE was performed in 1629 eyes of 1629 patients with a subjective refraction spherical equivalent (SEQ) of − 4.57 ± 1.20 D and 1414 eyes of 1414 patients with a subjective SEQ of − 4.53 ± 1.26 D in FS-LASIK. Refractive outcomes were recorded at 1 day, 1 week, and 1, 3, 6, and 12 months postoperatively. Predictors affecting myopic regression and other covariates were estimated with a Cox proportional hazard (Cox PH) model for the two surgical methods.

Results
At 12 months, no significant difference was evident in the efficacy (P = 0.934), predictability (P = 0.733), or stability (P = 0.66) between FS-LASIK and SMILE. The survival rates were 83.7% in the FS-LASIK group and 88.1% in the SMILE group. Multivariate analysis by the Cox PH model revealed a similar probability of postoperative myopic regression with SMILE or FS-LASIK (P = 0.630). Predictors of myopic regression included preoperative higher-order aberration root mean square with 3 mm pupil diameter (pre-HOA-RMS3) (P = 0.004), anterior chamber depth (ACD) (P = 0.015), pre-subjective sphere (P = 0.016), corneal diameter (P = 0.016), optical zone (OZ) (P = 0.02), and predicted depth of ablation (DA) (P = 0.003).

Conclusion
SMILE and FS-LASIK had a similar risk of myopic regression for low to moderate myopia. Pre-HOA-RMS3, ACD, pre-subjective sphere, corneal diameter, OZ, and predicted DA were predictors of myopic regression.
Surgical treatment of pediatric intractable frontal lobe epilepsy due to malformation of cortical development
Authors: Yu Hao , Lv Qiang , Liu Qingzhu , Wang Shuang , Ji Taoyun , Wang Ruofan , Wang Wen , Wang Dongming , Jiang Yuwu , Liu Xiaoyan , Cai Lixin 
Published: August 2022

Abstract
Background
Malformation of cortical development (MCD) is a common cause of intractable epilepsy in children. In this study, the effectiveness of frontal lobe epilepsy (FLE) surgery in children with intractable epilepsy due to MCD was assessed and its prognostic factors were studied.

Methods
Seventy-six patients with intractable FLE who received epilepsy surgery between January 2016 and March 2018 in Peking University First Hospital were recruited in this study. All the resected brain tissues were demonstrated to be MCD. All patients were followed up for at least 3 years. The clinical data and prognosis were analyzed retrospectively. Univariate and multivariate analyses were performed to investigate the correlations between clinical variables and prognostic outcome (Engel classification).

Results
Sixty (78.9%) patients had Engel class I postoperative outcome. The mean age at surgery was 6.00 ± 4.24 years. Sixty-six patients (86.8%) had daily seizures, 40.2% of the patients had epileptic spasm, and 33% of the patients had extensive interictal EEG abnormalities, which, however, could not provide any helpful information for localizing epileptogenic zones. About 29% of the patients had normal MRI findings even by experienced radiologists, and 26% of the patients had epileptogenic lesion involving adjacent lobes. There was a significant correlation between acute postoperative seizure (APOS) and prognosis (P < 0.05): APOS predicted poor prognosis. There was a significant correlation between pathology and prognosis (P < 0.05): FCD IA and FCD IIB were correlated with a good outcome. Both variables with a significance level of P < 0.05 during univariate analysis, including pathology and APOS, were included in multivariate analysis, which were significant independent predictors of prognosis.

Conclusions
The clinical manifestations of pediatric intractable FLE due to MCD are more complicated than those in adults. Multidisplinary presurgical evaluation in pediatric epilepsy is mandatory. The surgical outcome of pediatric FLE due to MCD could reach a seizure-free rate of 78.9% with the follow-up of at least 3 years. The post-operative pathology and APOS may be related to the prognosis of surgery in this group of pediatric patients.
The combined effect of policy changes and the covid-19 pandemic on the same day discharge and complications following total hip arthroplasty: a nationwide analysis
Authors: Gordon Adam M. , Magruder Matthew L. , Ng Mitchell K. , Sheth Bhavya K. , Conway Charles A. , Hang Jason Wong Che 
Published: August 2022

AbstractIntroductionAs a result of the SARS-CoV-2 (COVID-19) pandemic in 2020, elective surgeries, including total joint arthroplasty (TJA), were suspended nationwide. Concurrent removal of total hip arthroplasty (THA) from the Medicare inpatient-only list posed challenges to the delivery of quality patient care with low payor cost. Therefore, the objective of this study was to compare temporal trends in patient demographics, case volumes, length of stay, and complications following elective THA in the years 2019 to 2020 in the United States.MethodsThe 2019 to 2020 ACS-NSQIP database was queried for elective THA patients. Patients Pre-COVID (2019 and 2020Q1) were compared with post-COVID (2020Q2-Q4). THA utilization, demographics, 30-day complications, and length of stay (LOS) were compared between years. Linear regression evaluated changes in case volumes over time with significance threshold ofP < 0.05.ResultsA total of 77,797 patients underwent elective THA in 2019 (n = 43,667) and 2020 (n = 34,130), resulting in a 24.5% decline. Outpatient THA increased in 2020 (35.6%)vs. 2019 (5.7%) (P < 0.001). There was no significant difference in the volume of cases in 2019Q1 through 2019Q4 (P = 0.984). Elective THA volumes declined by 68.8% in 2020Q2, returned to pre-pandemic baseline in 2020Q3, before leveling off at 81.5% of baseline in Q4. Average LOS was significantly shorter in 2020 (1.55 days)vs. 2019 (1.78 days) (P < 0.001) and the proportion of same day discharge (SDD) increased quarterly from 2019 to 2020. There was no significant difference in the total complication rates in 2019 (6.6%)vs. 2020 (6.6%) (P = 0.831).DiscussionElective THA precipitously declined during the second quarter of 2020. The combined effect of policy changes and the COVID-19 pandemic resulted in a seven-fold increase in the number of surgeries performed in the outpatient setting in 2020. Rates of SDD doubled over the study period, despite no change in complication rates.