bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of depression and suicidal ideation in trauma patients in western Rajasthan
Authors: Baniya Girish Chandra , Kumar Surender , Verma Kamala 
Published: August 2022

Depression is a common psychiatric disorder in trauma patients. Early detection of depression in a traumatized patients can help alleviate long-term symptoms and adverse effects associated with depression. This study aimed to determine the prevalence of depression and suicidal ideation in trauma patients after one month of injury. Hospital-based cross-sectional study was carried out among 120 individuals with a history of trauma from March 2020 to May 2020. Purposive sampling was used to recruit participants over a specified period. The Beck's Depression Inventory-II (BDI-II) was used to measure depression intensity and suicidal ideation. The statistical analysis was carried out using SPSS version 20. The study included a total of 120 participants. The prevalence of depression was 30% in study participants. In our study, 8 (44.44%) of 18 participants over the age of 60, 30 (36.59%) of 82 male participants, 9 (64.29%) of 14 separated or divorced participants, 17 (45.95%) of 37 illiterate participants, 25 (43.86%) of 57 participants from low socioeconomic backgrounds, and 23 (42.59%) of 54 participants from rural backgrounds had more depression. Twenty (46.51%) out of 43 polytrauma participants, 5 (45.45%) out of 11 participants injured due to violence, 31 (33.70%) out of 92 participants who had a history of more than 48 hrs hospitalization, and 17 (48.57%) out of 35 participants had a history of ICU admission had more depression. Twenty-one participants (58.33%) of the 36 who suffered from depression had suicidal thoughts or intentions. Suicidal ideation and depression were more common in traumatic patients. Physicians' treatment should not be limited to early physical rehabilitation. They must also prioritise early mental rehabilitation in order to avoid long-term issues with mental and physical disabilities.
A study on serum calcium and magnesium levels in seizures disorders in pediatric age
Authors: Thummakomma Murali Krishna , Mandala Vinod Kumar , Siddhartha G , Chandra T Jaya 
Published: August 2022

Seizures are the most common neurologic disorder of childhood. A study was undertaken to find the correlation between serum Calcium and Magnesium levels and seizure disorders in pediatric age.It was a prospective case control time bound study, conducted in the department of paediatrics, Gandhi Medical College, Secunderabad. Study protocol was approved by the institutional ethics committee. Informed written consent was taken from the parents of the participants. Children of both gender, aged I month – 14 years with seizures were included, included in the test and non seizures in control category. After through clinical examination venous blood samples were collected for the estimation of serum electrolyte levels, 24 hours after onset of seizures on admission. T test was used to find the statistical significance and p &#62; 0.05 was considered statistically significance. The mean age was 8.6 and 7.8 years respectively in test and control groups. Seizures were diagnosed to be due togliosis, mesial temporal sclerosis, infarcts, hippocampal sclerosis, leighs disease.Statistically there was significant difference between the serum electrolyte levels.There was decrease in serum Ca and Mg levels with seizures. However, there was no correlation between serum electrolytes and severity of seizures.
Study of risk factors and prevalence of hypertension among type 2 diabetes patients
Authors: Arunkumar S , Sakthivel V , Babu R Praveen , Sathish.V Naveen 
Published: August 2022

According to the World Health Organization, hypertension is responsible for 13% of all deaths worldwide, making it a critical public health problem in developing and developed countries. Economic development, affluence, urbanization, and dietary westernization have contributed to a rise in the prevalence of type 2 diabetes mellitus (DM) and hypertension in South Asian countries. To study the prevalence of hypertension among adult type 2 diabetic patients and identify risk factors that may affect the development of hypertension in those patients. A cross-sectional study was conducted from May 2009 to May 2010 at the Department of Diabetology and Medicine Vinayaka Mission's Medical College & Hospital, Karaikal. 100 patients with Type 2 Diabetes of age 35 and above were screened and included in the study. Out of 100 patients with Diabetes Mellitus, 54 patients were hypertensive, and 46 were non-hypertensive. Hypertension was found to be more common in people aged 45 to 64.Our study reported that hypertension was present in 29% of males and 25% of females. Complications like neuropathy (9.3%) non-proliferative diabetic retinopathy (46.51%); proliferative diabetic retinopathy (4.65%); hypertensive retinopathy (2.33%); nephropathy (2.33%); ulcer foot (4.65%); coronary artery disease (27.9%) and stroke (2.33%) were observed in Diabetic patients and were identified as an independent risk factor for hypertension. It was also found that 31.94% of study populations were in the pre-hypertensive stage and 22.22% were in the second stage of hypertension. The prevalence of hypertension in patients with DM is high. Duration of diabetes was also one of the contributing factors for hypertension in Type 2 diabetes mellitus. It also concluded that the prevalence of hypertension increases with age advancement in DM.
Assessment of microbiological profile in peritoneal dialysis in patients with chronic kidney disease
Authors: Ramani CP , Sornaranjani M , Karuppasamy K 
Published: August 2022

Peritonitis is a serious complication of peritoneal dialysis (PD). It is the primary reason for hospitalization and switching over to hemodialysis. In the present study, we aimed to determine the microbiological profile of peritoneal dialysis fluid in patients with acute and chronic renal failure and identify these organisms' susceptibility patterns. This cross-sectional study was conducted in the Institute of Microbiology and Institute of Nephrology in the Rajiv Gandhi Government General Hospital from April 2016 to March 2017. A total of 100 patients who were &#62;18 years of age, acute and chronic renal failure patients who underwent Peritoneal Dialysis and patients on Continuous and Intermittent Peritoneal Dialysis were included. The study population included 100 patients who satisfied the inclusion criteria. 63% were males, and 37% were females. The patients had a mean age of 44.15±13.89. 28 samples were culture positive, out of which 13 (46.4%) were Gram-negative, 10 (35.7%) were Gram-positive and 5 (17.9%) were Fungal isolates. Among them, the majority were Acinetobacter baumannii (20%) and Candida non-albicans (20%), followed by Staphylococcus aureus (16%), Coagulase-negative Staphylococcus (16%), Klebsiella oxytoca (8%), Klebsiella pneumoniae (4%), Enterococcus faecalis (4%).Peritoneal infections were more common in patients with longer duration of dialysis and diabetes mellitus. CAPD patients were having a higher risk of infections compared to IPD. As the number of infections associated with peritoneal dialysis rises, routine PD fluid microbiological analysis after the procedure will help improve patient care by using appropriate antibiotics as soon as possible before any major clinical problem arises.
Pulmonary tuberculosis: An observational study to compare radiographic abnormalities with reference to smear microscopy status
Authors: Agarwal Dipti , Narayan Shamrendra , Agarwal Hemant Kr , Singh Arvind Kr , Pandey Manoj 
Published: August 2022

Interpretation of Chest X Ray (CXR) in relation to sputum smear microscopy can be useful in early diagnosis of pulmonary TB. The study aimed to compare the CXR findings in pulmonary TB cases with positive sputum microscopy and negative sputum microscopy. Patients with presumptive pulmonary TB were grouped into smear positive pulmonary TB and smear negative pulmonary TB groups based on CXR and sputum smear microscopy. CXR findings in the two groups were compared using chi square and students- t test. A total of 225 patients with presumptive pulmonary TB were evaluated. Of these, 174 subjects were included in the study: 129 (74.2%) in smear positive pulmonary TB group and 45(25.8%) in smear negative pulmonary TB group. Parenchymal involvement was the most common finding in both smear positive and smear negative groups seen in 118 (91.5%) and 42 (93.3%) subjects, respectively. The area of parenchymal involvement was significantly more in smear positive group as compared to smear negative group (p&#60;0.001). Cavitation was more commonly associated with smear positive group (p=0.005) Nodal enlargement was significantly more common among smear negative subjects (p&#60;.001). CXR could detect 25.8% smear negative pulmonary TB cases. Extensive parenchymal infiltration and cavitation were more commonly associated with smear positive patients whereas nodal involvement was significantly more common in smear negative patients.
Prescribing pattern of drugs amongst COVID-19 patients in a medical college hospital
Authors: Agrawal V K , Agrawal Pooja , Singhal Aditya 
Published: August 2022

This study was conducted to studyprescribing pattern of drugs amongst mild to moderate COVID-19 patients in COVID dedicated medical college hospital in northern India. : A retrospective, descriptive study was conducted in a COVID dedicated medical college hospital at Uttar Pradesh India. Demographic data, hospitalization data, and drug utilization pattern of all laboratory confirmed mild to moderate COVID-19 patients of all age groups, either sex, and admitted between 01 July 20 to 30 September 2020 were retrieved and analyzed. Out of 767 COVID-19 patients 66.62% were male and 33.38% were female. Mean age of COVID-19 patients were 51 years. Average numbers of drug prescribed per patients were seven. Number of drug prescribed per patients increased in older COVID-19 patients and COVID-19 patients having co-morbidities. Most common prescribed drug was paracetamol (100%), followed by Vitamin C (99.08%), followed by multivitamins (97.78%), followed by protonpump inhibitors (74.84%), followed by antihistaminices in 51.89% cases followed by hydroxychloroquine and Ivermectin was prescribed in 47.84% cases. Most common antibiotic prescribed was Amoxicillin (40.94%), followed by Azithromycin (34.41%), and followed by Doxycycline (29.20%) cases. Flavipiravir was prescribed in 15.12% cases. Corticosteroids were prescribed in 16.30% cases. Drug used for admitted COVID-19 patients were diverse and were in accordance to existing guidelines.
Clinical presentation of orbital mucormycosis in North –West Rajasthan: An observational study
Authors: Bhargava Poonam , Joshi Rashmi , Yadav Dinesh Kumar , Maherda Lakshita , Sharma Gargi , Jangir Shilpa 
Published: August 2022

India has witnessed severe complications after the second wave of global covid 19 pandemic. The new covid virus variant is so much lethal that it causes severe immunodepression in the covid survivors, and makes them prone to the opportunistic and rare mucormycosis infection. To see the spectrum of ocular manifestations in the patients of post Covid 19 mucormycosis.This was an observational study, carried out at tertiary care centre in North - West Rajasthan. Patients of mucormycosis during second wave of covid 19 pandemic in the month of April and May were included in the study. covid was diagnosed either by reverse transcriptase polymerase chain reaction (RTPCR) / high resolution computed tomography HRCT. Routine blood investigation, contrast enhanced magnetic resonance imaging (CEMRI) of paranasal sinuses, orbit and brain was done. Pottasium hydroxide (KOH) mount of nasal swab/biopsy was done for confirmation. Thorough ocular examination was done according to the preformed proforma. Out of 61 patients of mucormycosis, 47 patients had ocular involvement varying from common symptoms like lid edema, chemosis, proptosis to sight threatening central retinal artery occlusion (CRAO), Orbital Apex Syndrome and Panophthalmitis. A rare presentation of corneal ulcer and corneal eschar was also seen. Rhino orbital cerebral mucormycosis is a vision and life threatening opportunistic infection. A high index of clinical suspicion and early diagnosis with multi-disciplinary approach for the treatment can save the life of the patient.
A study of clinical profile and outcome of malaria in adults at government general hospital, Nizamabad
Authors: Kumar Ch Subhash , Prashanth D , Kumar D Sharath , Reddy M Harikrishna 
Published: August 2022

What has to be stressed is the need to be cautious with such individuals and to broaden our differentials to include P. vivax as a possible cause of severe malaria. Patients who are aggressively handled and treated can have a better outcome.To study the clinical profile and outcome of malaria in adults at Government General Hospital in our local area. A Cross-sectional, observational study done in Department of general medicine in Fifty smear positive malaria patients admitted to the medical wards and intensive care units are included in the study. Study done for a period of 1 Year . Patients of either gender, above 18 years of age and below 60 years of age, diagnosed with malaria on peripheral smear were included in study.: A total number of 50 smear positive malaria patients were included in the study. Majority of the patients belongs to the age group of 18-30 years [36%] CNS findings: Altered Sensorium was seen in 20% patients and convulsions were seen in 20% patients. Complicated malaria was present in 76% patients and uncomplicated malaria was present in 24% patients. Complicated falciparum malaria was present in 30% patients and Complicated Vivax malaria was present in 46% patients. Uncomplicated falciparum malaria was present in 4% patients and Uncomplicated Vivax malaria was present in 20% patients. Mortality was seen in 6% patients. Mortality was seen in the age group of 41- 50 years [66.7%] and 31-40 years [33.3%]. : Malaria complications can be reduced by studying the clinical profile of the disease and using proper antimalarial medication treatment. This aids in the reduction of malaria morbidity and death, as well as the country's long-term economic prosperity.
Comparative study of UTI in high-risk pregnant patients and patients attending to ANC clinics
Authors: Gunjal Roopali , S Deepa , C Ravindranath , Mundary Sakuntala , Kavatagi Kiran , Sonawane Sonal 
Published: August 2022

Asymptomatic bacteriuria, UTI and pyelonephritis increase risk of preterm labour and premature rupture of the membranes which results indirectly in worse foetal outcome which was highlighted in this study. Also, the number of drug resistant pathogens are increasing as these high-risk pregnant patients are more prone for instrumentation, procedures which indirectly exposes the patients to hospital acquired pathogens. In this prospective study, a total of 200 mid-stream urine samples were collected aseptically from randomly selected high risk pregnant women (100) and (100) from normal ANC patients attending ANC clinics. Out of 100 samples in high-risk pregnancy patients, 44% yielded monobacterial growth, 8% yielded polybacterial growth. was most common (46%), (25%), (15.3%), 3.8%, 2%. 26.9% showed growth &#62;10CFU/ml, 32.6% showed growth 10– 10 CFU/ml, 15.3% showed growth &#60;10 CFU/ml. Out of 100 samples from normal ANC patients all showed monobacterial growth(42%). . was most common organism isolated 56.2% followed by Escherichia coli 26%, 4%, 2%, 2%. All organisms showed growth range in between 10³CFU/ml to 10⁵CFU/ml. None of the isolate was pan drug resistant as compared to complicated pregnancy subset. So, there should be a proper management guideline whenever the pregnant females presents with complication. The organism should always be tested for sensitivity before starting empirical antibiotic treatment. Also, the number of ANC visits should be monitored judiciously as to know if we are not unknowingly bombarding the pathogens in normal patients.
Comparison of syphilis testing by reverse algorithm and conventional method among blood donors in a tertiary care center
Authors: Bhaskaran Ramesh , Sasidharan Athira , Baiju Nithya M , Rafi A.M , Valsan Chithra 
Published: August 2022

Traditional testing algorithm for syphilis begins with screening non-treponemal test followed by confirmatory treponemal test. Reverse algorithm first screens with a treponemal test; reactive samples are then tested by Rapid plasma reagin test (RPR) which is used to assess disease activity. Discordant syphilis IgG and RPR results are resolved by a second treponemal test, Treponema pallidum hemagglutination assay (TPHA) as recommended by the Centres for Disease Control and Prevention laboratories. To evaluate the analytical performance of reverse algorithms in syphilis infection among donors in comparison with traditional methods and the prevalence of syphilis among blood donor populations.This was a cross sectional study done in the department of transfusion medicine from January 2019 to February 2020 which comprised of 8635 blood donors. After donation all the blood samples were screened for syphilis using chemiluminescent immunoassay (Vitros syphilis TPA assay) in Vitros 3600 EQ/ECIQ immunodiagnostic system and RPR (omega RPR test kit) irrespective of each other’s result. Whenever chemiluminescence immunoassay or RPR turns positive, the samples were sent for TPHA (Immutrep TPHA test kit) keeping it as the gold standard method.Among 8635 samples tested, seroreactivity of CLIA (Vitros syphilis TPA assay) was 0.25 % whereas for traditional algorithm 0.13%. Sensitivity, specificity and accuracy of reverse algorithm in comparison with traditional was 100 %, 70.6%, 78.3% and 36.4% ,75% and 65.1% respectively. In comparison with TPHA, Vitros TPA assay in reverse algorithm showed moderate agreement (k=0.56, p=0) which was statistically significant whereas RPR showed slight agreement (k=0.11, p=0.47). Negative predictive value of CLIA was 100% (p=0) which was statistically significant. Positive predictive value of reverse algorithm was 54.5% and 33.3% for traditional algorithm (p=0.04).
Study of ECG changes in different thyrotoxic states and their correlation with thyroid hormone levels
Authors: Chouhan Bhupendra , Verma Rajesh , Razdan Monica , Bordiya Narendra , Sharma Shiv Shankar , Bansal Pankaj 
Published: August 2022

: Thyroid hormone has many recognized effects on the cardiovascular system that results in significant comorbidity and may also affect the quality of life of diseased person. : To assess the ECG changes in thyrotoxicosis with thyroid hormone level and secondary objectives are to compare different ECG pattern in thyrotoxicosis patients (Graves’ disease, Toxic multinodular goiter, Thyroid adenoma) with healthy individual taken as controls after exclusion of cardiovascular disorder, Hypertension.: Observational prospective case-controlled study include minimum 50 thyrotoxicosis patients and 50 control, done at Department of General Medicine MGM Medical college and MY Hospital Indore (MP). : In the present study peak incidence of thyrotoxicosis was observed in the age group of 35-50 years (50%), followed by in the age group of 20-34 years (36%). The female: male ratio in thyrotoxic group is 5.25:1. In this study Graves’ disease accounts most of the cases of thyrotoxic patients i.e., 84%. Sinus tachycardia was observed in 88.09% of Graves’ disease, 40% of toxic multinodular goiter, and 100% of thyroiditis. Atrial fibrillation was observed in 7.1% of Graves’ disease and 60 % of toxic multinodular goiter. Also, sinus tachycardia was observed in 63% of thyrotoxic patients who had free T3 level &#62;2.4 ng/ml, in 100% of thyrotoxic patients who had free T3 level from 1.39-2.4 ng/ml, and in 81.8% of thyrotoxic patients who had free T3 level from 0.486-1.38 ng/ml. Atrial fibrillation was observed in 31.5% of thyrotoxic patients who had free T3 level &#62;2.4 ng/ml. The patients having free T3 level from 1.39-2.4 ng/ml and 0.486-1.38 ng/ml does not show atrial fibrillation in ECG. The peak incidence of the thyrotoxicosis was found in the age group of 35-50 years (50%), younger patients age group of 20-50 years accounts 86% of total thyrotoxic patients and females were more affected than male. Graves’ disease accounts 84% cases of thyrotoxicosis. Thyrotoxic group and euthyroid group shows statistically significant ECG changes in terms of sinus tachycardia (&#60;0.0001) and atrial fibrillation (0.0256). In the thyrotoxic group 82% of patient shows sinus tachycardia and 12% of patient shows atrial fibrillation. The association between sinus tachycardia, atrial fibrillation and total T3 level and free T3 level was found statistically significant (P=0.007).
Особливості трансформації ринку транспотрно-логістичних послуг в Україні
Authors: Новальська Надія , Клименко Вікторія , Москаленко Олена , Селіщев Сергій 
Published: August 2022

В статті проаналізовано особливості та фактори, які вплинули на процес прискорення трансформування ринку транспортно-логістичних послуг в Україні. За результатами аналізу процесу розвитку ринку транспортно-логістичних послуг в Україні за часів незалежності виокремлено чотири етапи його формування, а саме: перший етап (початок 1990-х років) характеризувався низьким рівнем логістичного обслуговування транспортних та складських процесів, ігноруванням принципів логістики; другий етап (друга половина 1990-х років) характеризувався активізацією процесів побудови системи дистрибуції, формуванням нових партнерських відносин з усіма учасниками ринку, розвитком торгівельного бізнесу та оновленням системи складування, транспортування та просування продукції, виходом на український ринок міжнародних логістичних операторів; третій етап (перше десятиліття ХХІ ст.) ознаменувався появою перших національних логістичних компаній (2PL- та 3PL-провайдерів), які надавали послуги на рівні міжнародних вимог; четвертий етап (друге десятиліття ХХІ ст.) характеризувався розвитком 3PL та 4PL операційної діяльності, передачею торговельними та промисловими підприємствами логістичних функцій на аутсорсинг, зміною підходу до роботи з клієнтами. Проаналізовано результати оцінки Світовим банком рівня ефективності логістичної системи в Україні в розрізі окремих показників та в динаміці, а також результати експертного дослідження загального стану розвитку транспортної інфраструктури, проведені Європейською Бізнес Асоціацією. Визначено фактори, які стримують розвиток ринку транспортно-логістичних послуг в Україні. На основі проведеного дослідження виокремлено позитивні тенденції, які нині спостерігаються на вітчизняному ринку транспортно-логістичних послуг та обґрунтовано складові його розвитку відповідно до сучасних міжнародних вимог.