bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of near-infrared spectroscopy to estimate physical, anatomical and hydraulic properties ofEucalyptuswood
Authors: Barotto Antonio José , Martínez-Meier Alejandro , Segura Vincent , Monteoliva Silvia , Charpentier Jean-Paul , Gyenge Javier , Sergent Anne Sophie , Millier Frédéric , Rozenberg Philippe , Fernández María Elena 
Published: November 2022

AbstractTree breeding programs and wood industries require simple, time- and cost-effective techniques to process large volumes of samples. In recent decades, near-infrared spectroscopy (NIRS) has been acknowledged as one of the most powerful techniques for wood analysis, making it the most used tool for high-throughput phenotyping. Previous studies have shown that a significant number of anatomical, physical, chemical and mechanical wood properties can be estimated through NIRS, both for angiosperm and gymnosperm species. However, the ability of this technique to predict functional traits related to drought resistance has been poorly explored, especially in angiosperm species. This is particularly relevant since determining xylem hydraulic properties by conventional techniques is complex and time-consuming, clearly limiting its use in studies and applications that demand large amounts of samples. In this study, we measured several wood anatomical and hydraulic traits and collected NIR spectra in branches of two Eucalyptus L'Hér species. We developed NIRS calibration models and discussed their ability to accurately predict the studied traits. The models generated allowed us to adequately calibrate the reference traits, with high R2 (≥0.75) for traits such as P12, P88, the slope of the vulnerability curves to xylem embolism or the fiber wall fraction, and with lower R2 (0.39–0.52) for P50, maximum hydraulic conductivity or frequency of ray parenchyma. We found that certain wavenumbers improve models’ calibration, with those in the range of 4000–5500 cm−1 predicting the highest number of both anatomical and functional traits. We concluded that the use of NIRS allows calibrating models with potential predictive value not only for wood structural and chemical variables but also for anatomical and functional traits related to drought resistance in wood types with complex structure as eucalypts. These results are promising in light of the required knowledge about species and genotypes adaptability to global climatic change.
Targeting exon 20 insertion mutations in lung cancer
Authors: Yang Yaning , Wang Yan 
Published: November 2022

Purpose of review
The application of tyrosine kinase inhibitor (TKI) has successfully changed the standard of care in epidermal growth factor receptor (EGFR) positive non-small cell lung cancer. However, clinical survivals for patients with EGFR exon 20 insertions have failed to improve over the long period and the mutation appeared resistant to EGFR-TKIs. This overview focused on the current treatment strategies, summarized the emerging regimens for patients with EGFR exon 20 insertions, and demonstrated historical challenges and future development.

Recent finding
Current clinical trials suggested that several regimens selectively-targeted EGFR exon 20 insertions presented potent antitumor activity, like mobocertinib and the bispecific anti-EGFR-MET monoclonal antibody amivantamab and were approved by Food and Drug Administration (FDA) in patients progressed beyond first-line treatment. Novel treatments, including DZD9008, CLN-081, revealed modest clinical efficacy as well and clinical trials are underway, which may lead to improvement of survival outcomes.

Summary
Recent clinical evidence indicates that targeted therapies could improve survival benefits to some extent. More efforts on drug development are underway to bring higher response rates both extracranial and intracranial, sustained clinical remission, and better survival benefits.
Multiomic analysis reveals microbiome-related relationships between cocaine use and metabolites
Authors: Martinez Sabrina Sales , Stebliankin Vitalii , Hernandez Jacqueline , Martin Haley , Tamargo Javier , Rodriguez Jose Bastida , Teeman Colby , Johnson Angelique , Seminario Leslie , Campa Adriana , Narasimhan Giri , Baum Marianna K. 
Published: November 2022

Objective:
Over 19 million individuals globally have a cocaine use disorder, a significant public health crisis. Cocaine has also been associated with a pro-inflammatory state and recently with imbalances in the intestinal microbiota as compared to nonuse. The objective of this pilot study was to characterize the gut microbiota and plasma metabolites in people with HIV (PWH) who use cocaine compared with those who do not.

Design:
Cross-sectional study.

Methods:
A pilot study in PWH was conducted on 25 cocaine users and 25 cocaine nonusers from the Miami Adult Studies on HIV cohort. Stool samples and blood plasma were collected. Bacterial composition was characterized using 16S rRNA sequencing. Metabolomics in plasma were determined using gas and liquid chromatography/mass spectrometry.

Results:
The relative abundances of the Lachnopspira genus, Oscillospira genus, Bifidobacterium adolescentis species, and Euryarchaeota phylum were significantly higher in the cocaine- using PWH compared to cocaine-nonusing PWH. Cocaine-use was associated with higher levels of several metabolites: products of dopamine catabolism (3-methoxytyrosine and 3-methoxytyramine sulfate), phenylacetate, benzoate, butyrate, and butyrylglycine.

Conclusions:
Cocaine use was associated with higher abundances of taxa and metabolites known to be associated with pathogenic states that include gastrointestinal conditions. Understanding key intestinal bacterial functional pathways that are altered due to cocaine use in PWH will provide a better understanding of the relationships between the host intestinal microbiome and potentially provide novel treatments to improve health.
Oxygen saturation probe-related pressure injury prevention in children on an inpatient pediatric unit: a best practice implementation project
Authors: Carroll Amy L. , Palokas Michelle , Linnell Shelbi 
Published: November 2022

ABSTRACT

Objectives:
The aim of this project was to increase compliance with rotation and documentation of rotation of oxygen saturation probes to reduce medical-device-related pressure injuries in children on a pediatric inpatient unit.

Introduction:
There are a multitude of factors that place hospitalized children at an increased risk for medical-device-related pressure injuries. Evidence supports the rotation of medical devices, if appropriate, at least twice daily to minimize the risk of medical-device-related pressure injuries in hospitalized children.

Methods:
The project used JBI's Practical Application of Clinical Evidence System and Getting Research into Practice audit tool for encouraging evidence-based practices. A baseline audit was conducted, followed by the implementation of targeted strategies. The project was completed with a follow-up audit to determine change in practice.

Results:
The baseline audit revealed significant deficits in two of the seven audit criteria. Barriers to the rotation of oxygen saturation probes and the assessment of skin under oxygen saturation probes were identified by the project team and an electronic health record (EHR) documentation change was implemented. Follow-up audits were not conducted on the five criteria that showed high compliance at baseline. For the remaining two audit criteria, data revealed no improvement in one of the criteria (3% compliance at both baseline and follow-up audits) and an increase from 0% compliance to 43% compliance in the second criterion.

Conclusion:
Optimizing EHR documentation, specifically ease and efficiency of EHR documentation, has the potential to positively impact clinical practice.
Control of cell proliferation by memories of mitosis
Authors: Meitinger Franz , Davis Robert L. , Martinez Mallory B. , Shiau Andrew K. , Oegema Karen , Desai Arshad 
Published: November 2022

AbstractMitotic duration is tightly constrained, with extended mitotic duration being a characteristic of potentially problematic cells prone to chromosome missegregation and genomic instability. We show that memories of mitotic duration are integrated by a p53-based mitotic stopwatch pathway to exert tight control over proliferation. The stopwatch halts proliferation of the products of a single significantly extended mitosis or of successive modestly extended mitoses. Time in mitosis is monitored via mitotic kinase-regulated assembly of stopwatch complexes that are transmitted to daughter cells. The stopwatch is inactivated in p53-mutant cancers, as well as in a significant proportion of p53-wildtype cancers, consistent with classification of stopwatch complex subunits as tumor suppressors. Stopwatch status additionally influences efficacy of anti-mitotic agents currently used or in development for cancer therapy.One-Sentence SummaryTime spent in mitosis is carefully monitored to halt the proliferation of potentially dangerous cells in a population.
Electrical Stimulation of Human Mesenchymal Stem Cells on Conductive Chitosan-Polyaniline Substrates Promotes Neural Priming
Authors: Eftekhari Behnaz Sadat , Song Dawei , Janmey Paul A. 
Published: November 2022

AbstractElectrical stimulation (ES) within conductive polymer substrates has been suggested to promote the differentiation of stem cells toward a neuronal phenotype. The use of conductive scaffolds in tissue regeneration provides a unique and attractive new option to control the amount and location of ES delivery. Scaffold stiffness has also been shown to be an important regulator of stem cells’ behavior and fate. Therefore, to improve stem cell-based regenerative therapies, it is essential to characterize the simultaneous effects of electroconductive substrate stiffness and electric field stimuli on stem cell fate processes. In this study, biodegradable electroconductive substrates based on chitosan-polyaniline (CS-g-PANI) were fabricated with different stiffnesses. Human mesenchymal stem cells (hMSCs) seeded on these scaffolds were electrically stimulated for 14 days with 100 mV/ cm (20 min every day). For hMSCs cultured on soft conductive scaffolds, a morphological change with significant filopodial elongation was observed after 2 weeks of electrically stimulated culture. Compared with stiff conductive CS-g-PANI scaffolds and non-conductive CS scaffolds, for soft conductive CS-g-PANI scaffolds microtubule-associated protein 2 (MAP2) and neurofilament (NF-H) expression increased after application of ES. At the same time, there was a decrease in the expression of the glial markers glial fibrillary acidic protein (GFAP) and vimentin after ES. Furthermore, the elevation of intracellular calcium [Ca2+] during spontaneous, cell-generated Ca2+transients further suggested that electric field stimulation of hMSCs cultured on conductive CS-g-PANI substrates can promote a neural-like phenotype. Our findings propose that the combination of the soft conductive CS-g-PANI substrate and ES is a promising new tool for enhancing nerve tissue engineering outcomes.
Efficient high-resolution electric and magnetic field simulations inside the human body in the vicinity of wireless power transfer systems with varying models
Authors: Haussmann Norman , Mease Robin , Zang Martin , Stroka Steven , Hensel Hendrik , Clemens Markus 
Published: November 2022

Purpose
Magneto-quasi-static fields emanated by inductive charging systems can be potentially harmful to the human body. Recent projects, such as TALAKO and MILAS, use the technique of wireless power transfer (WPT) to charge batteries of electrically powered vehicles. To ensure the safety of passengers, the exposing magnetic flux density needs to be measured in situ and compared to reference limit values. However, in the design phase of these systems, numerical simulations of the emanated magnetic flux density are inevitable. This study aims to present a tool along with a workflow, based on the Scaled-Frequency Finite Difference Time-Domain and Co-Simulation Scalar Potential Finite Difference schemes, to determine body-internal magnetic flux densities, electric field strengths and induced voltages into cardiac pacemakers. The simulations should be time efficient, with lower computational costs and minimal human workload.

Design/methodology/approach
The numerical assessment of the human exposure to magneto-quasi-static fields is computationally expensive, especially when considering high-resolution discretization models of vehicles and WPT systems. Incorporating human body models into the simulation further enhances the number of mesh cells by multiple millions. Hence, the number of simulations including all components and human models needs to be limited while efficient numerical schemes need to be applied.

Findings
This work presents and compares four exposure scenarios using the presented numerical methods. By efficiently combining numerical methods, the simulation time can be reduced by a factor of 3.5 and the required storage space by almost a factor of 4.

Originality/value
This work presents and discusses an efficient way to determine the exposure of human beings in the vicinity of wireless power transfer systems that saves computer simulation resources and human workload.
Optimization of service scheduling problem for overlapping tower cranes with cooperative coevolutionary genetic algorithm
Authors: Yin Jing , Li Jiahao , Yang Ahui , Cai Shunyao 
Published: November 2022

PurposeIn regarding to operational efficiency and safety improvements, multiple tower crane service scheduling problem is one of the main problems related to tower crane operation but receives limited attention. The current work presents an optimization model for scheduling multiple tower cranes' service with overlapping areas while achieving collision-free between cranes.Design/methodology/approachThe cooperative coevolutionary genetic algorithm (CCGA) was proposed to solve this model. Considering the possible types of cross-tasks, through effectively allocating overlapping area tasks to each crane and then prioritizing the assigned tasks for each crane, the makespan of tower cranes was minimized and the crane collision avoidance was achieved by only allowing one crane entering the overlapping area at one time. A case study of the mega project Daxing International Airport has been investigated to evaluate the performance of the proposed algorithm.FindingsThe computational results showed that the CCGA algorithm outperforms two compared algorithms in terms of the optimal makespan and the CPU time. Also, the convergence of CCGA was discussed and compared, which was better than that of traditional genetic algorithm (TGA) for small-sized set (50 tasks) and was almost the same as TGA for large-sized sets.Originality/valueThis paper can provide new perspectives on multiple tower crane service sequencing problem. The proposed model and algorithm can be applied directly to enhance the operational efficiency of tower cranes on construction site.
Exploring country differences in the adoption of mobile payment service: the surprising robustness of the UTAUT2 model
Authors: Wu Zhongda , Liu Yunxin 
Published: November 2022

PurposeThis paper investigated the extent to which the predictive power of the Unified Theory of Acceptance and Use of Technology 2 (UTAUT2) was robust against cultural variations and to what extent its predictive power could be improved by including face-valid individual differences (i.e. perceived risk and personal innovativeness) and cultural factors (i.e. individualism and uncertainty avoidance).Design/methodology/approachData were collected from web surveys of Chinese, American and Belgian mobile Internet users (total n = 1,068).FindingsThe authors found that the UTAUT2 model was less predictive in the country where the adoption of mobile payment service (MPS) is high (i.e. China). In contrast, the UTAUT2 model was more predictive in countries where the adoption of MPS is lower (i.e. the United States and Belgium). The authors did not find additional variance explained by individual differences. Regarding the cultural variables, the authors found that individualism moderated the effect of social influence on behavioral intention to use MPS, such that the effect was more substantial among people with individualistic cultural traits. However, the authors found no moderation effect of uncertainty avoidance.Originality/valueThis research contributes to existing work on technology acceptance by exploring whether it is helpful to introduce individual and cultural factors into the UTAUT2 model when predicting technology adoption in different cultures. This research further examines the moderating role of cultural factors in predicting the adoption of MPS. The authors conclude that the UTAUT2 model is generally robust and appears to capture the predictive of face-valid individual and cultural factors.
Learning through exploitative and exploratory overseas R&D: impacts on EMNEs' innovation performance
Authors: Zhong Xi , Chen Weihong 
Published: November 2022

PurposeThis study aims to examine whether exploitative and exploratory overseas R&D have independent and significant effects on emerging economy multinational enterprises' (EMNEs’) innovation performance and whether top management team (TMT) nationality diversity and openness have a moderating effect on these relationships.Design/methodology/approachThis study analyzes data collected from Chinese-listed manufacturing enterprises for 2007 to 2018.FindingsEmpirical results show that both exploitative and exploratory overseas R&D can help improve EMNEs' innovation performance. The authors further find that TMT nationality diversity and TMT openness strengthen the aforementioned relationships.Originality/valueThis study presents the first empirical evidence showing whether and when exploitative and exploratory overseas R&D have independent and heterogeneous effects on EMNEs' innovation performance.
Inclusivity in sports: fan attitudes and behaviors towards nonbinary athletes
Authors: Elmadag A. Banu , Yaoyuneyong Gallayanee , Burgess Brigitte 
Published: November 2022

PurposeThis study aims to examine diversity and inclusivity in sports from a sexual orientation perspective. A literature review summarizes known findings on attitudes and perceptions of and towards nonbinary individuals in sports. Adopting Herek’s (2007) Sexual Stigma perspective, an experiment is conducted exploring the differences in fan attitudes and behavioral intentions towards nonbinary athletes in both women’s and men’s sports.Design/methodology/approachA systematic review of extant literature identified 24 peer-reviewed primary studies examining nonbinary individuals in sports. A 2 (Sport: Women’s vs. Men’s Basketball) × 2 (Nonbinary Indicator: Indicator vs. No-Indicator) experimental study was then designed to further explore fan attitudes towards nonbinary athletes.FindingsThe study revealed that, among sports fans, there was no perceived performance difference in women’s or men’s basketball linked to athletes’ nonbinary status (as measured by athletic ability, future performance, sportsmanship, talent and quickness). However, measures of fan support (sport engagement, intention to buy team merchandise and team fanship) were lower when the athlete was perceived as nonbinary. For women’s basketball, team fanship and intention to buy team merchandise were significantly lower, while the difference was not significant in men’s basketball.Originality/valueAlong with an inclusive review of prior literature, this is the first empirical study to examine the differences in fans’ attitudes towards nonbinary athletes in both women’s and men’s sports at the same time via an experimental design.
“Giving PUMA the boot”–A case study of a contemporary consumer sports boycott
Authors: Dart Jon 
Published: November 2022

PurposeThe purpose of this article is to offer a conceptual assessment of a contemporary consumer boycott of a global sports brand. A critical commentary is offered of the “Boycott PUMA” campaign with an examination of the positions and motivations of the different parties involved, specifically PUMA, the “Boycott PUMA” campaign, the Israeli Football Association and UEFA/FIFA.Design/methodology/approachThis article is a position and conceptual paper, designed to generate a discussion on what is an emotive consumer boycott campaign. A distinction is made between political boycotts and consumer boycotts, whether it is possible to separate sport from politics, and if PUMA's claimed position of neutrality in this conflict can be achieved.FindingsThe focus here is on PUMA's corporate social responsibility statement in which they claim that sport and politics do not mix, with their response to Russia's invasion of Ukraine in 2022 undermining this claim. PUMA's commitment to social justice is being used by the “Boycott PUMA” activists to expose the disconnect between PUMA's stated vision and its actions.Practical implicationsPUMA's brand has been built on creating a particular type of brand image, with a positive image and brand awareness essential for this sports apparel company. If the company finds itself in a media spotlight their brand equity can become damaged.Originality/valueWith very little research available on the Israel/Palestine from a sport sponsorship and marketing perspective, this article offers an original and much needed assessment of a potentially significant campaign.
Exploring smart retailing: anthropomorphism in voice shopping of smart speaker
Authors: Jang Yu-Teng Jacky , Liu Anne Yenching , Ke Wen-Yu 
Published: November 2022

PurposeThe purpose of this paper is to investigate the effects of anthropomorphism and identify factors related to adopting voice shopping on smart speakers.Design/methodology/approachProgress in partial least squares structural equation modeling (PLS-SEM) approach is used to test the proposed research framework regarding anthropomorphism and user perceptions on voice shopping via smart speakers. Individuals' responses to questions about attitude and intention to use voice shopping via smart speakers were collected and analyzed.FindingsThe results showed that anthropomorphism had a positive influence on satisfaction, which, in turn, had a positive impact on intention to adopt voice shopping, and customers had positive opinions regarding smart speakers.Research limitations/implicationsThis study only reflects a younger perspective on smart speaker voice shopping. This study identified the characteristics of smart speakers that increase customers' intention to purchase, which can be used to formulate sales strategies and management guidelines.Practical implicationsThis research provided a new perspective to enable practitioners to promote smart speakers for voice shopping. Smart speaker manufacturers can utilize the findings of this research to improve the system design of smart speakers to further facilitate voice shopping.Originality/valueUnlike previous studies, which focused on product attributes of smart speakers or voice shopping experiences, this study provided a clear picture of how the anthropomorphic feature of smart speakers affects customers' intention to adopt voice shopping.