bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design and Analysis of a Novel Experiment Platform for 3D Needle Insertion Based on Orthogonally Arranged Dual Camera
Authors: Du Shilun , Li Murong , Xu Tian , Hu Yingda , Wang Zhen , Lei Yong 
Published: September 2022

Abstract
3D needle insertion is important both in theoretical research and clinic practice. In literature, most needle insertion experiments use 2D experiment platforms. A few studies use 3D experiment platforms based on ultrasound or traditional stereo camera. The ultrasound has low resolution and traditional stereo camera is difficult to reconstruct objects without textures, which is not suitable for markers reconstruction. Hence, it is needed to design a 3D needle insertion experiment platform with high resolution and 3D reconstruction ability. In this paper, we design a 3D needle insertion platform based on the orthogonal-arranged dual camera. Error analysis and accuracy verification are carried out as well. First, experiment platform framework is designed and essential modules are introduced. Second, the error analyses based on Frechet distance are carried out to quantify the error led by the bevel facing angle and insertion angle. Third, to verify the 3D reconstruction accuracy, the 2D distance sensitivity experiments and 3D reconstruction experiments are carried out for the dual camera system. The accuracy of 3D reconstruction in the region of interest has been verified. To optimize the 3D needle insertion platform, a needle holder to ensure concentricity is applied. Besides, pre-insertion process and orthogonal-arranged double chessboard calibration are introduced into setup procedures. Finally, a 3D needle insertion experiment platform is designed and validated through needle path planning algorithm verification. Results show that the proposed experiment platform can steer the needle accurately and reconstruct the needle path and markers in acceptable accuracy.
A Modified Schlieren System for In-Situ Voxel Growth Observation in Projection-Based Stereolithography Process
Authors: Chivate Aditya , Zhou Chi 
Published: September 2022

Abstract
Digital maskless lithography is growing in popularity due to its unique ability to fabricate high-resolution parts at a fast speed without the need for physical masks. With controlled grayscaling and exposure control, it has the potential to replace conventional lithography. Though the theoretical foundation for photopolymerization exists, it is difficult to observe the voxel growth process in situ. This can be attributed to the low refractive index difference between cured and uncured resin, the microscopic size of the parts, and the rapid rate of photopolymerization after crossing the threshold. Therefore, a system that can address these issues is highly desired. Schlieren optics is a tool that makes the minute changes in the refractive indices visible. This paper proposes a modified schlieren-based observation system with confocal magnifying optics that create a virtual screen at the focal plane of the camera. The proposed technique visualizes the light deflection by the changing density induced refractive index gradient, and the use of focusing optics enables flexible positioning of the virtual screen and optical magnification. Single-shot binary images with a different number of pixels were used for fabricating voxels. Different factors affecting the voxel shape like chemical composition, energy input are studied. The observed results are compared against simulations based on Beer-Lambert’s law, photopolymerization curve, and Gaussian beam propagation theory. The physical experimental results demonstrated the effectiveness of the proposed observation system.
3D Printing of Designed Ultra-Low Loss Microwave Dielectrics for Beyond 5G Applications
Authors: Ghosh Avishek 
Published: September 2022

Abstract
Low-temperature sintering ceramics with high dielectric permittivity and low loss are highly valuable to the communication industry. Additive Manufacturing (AM) exhibits excellent potential to process a wide range of engineering materials and deliver complex three-dimensional structures in various scales, with several benefits over traditional manufacturing methods used in electronics manufacturing. Therefore, the advent of AM has offered a radically new way of designing and manufacturing electronic and communication components with tailored performance. In this work, a stable ink has been formulated from ultra-low loss dielectric bismuth molybdate (Bi2Mo2O9) ceramics. The formulated ink exhibited suitable rheological properties responsive to the direct ink writing technique. The 3D printed components with good structural integrity and spatial resolution were sintered at 670°C for 4 hours using the conventional heating method, achieving &gt; 94% density. A series of components with varying shapes and designed porosities were fabricated using the extrusion 3D printing method. The relative permittivity (εr) and loss tangent (tanδ) for the 3D printed and sintered Bi2Mo2O9 solid components were found to be 36.5 and 0.0005, respectively, at ∼8GHz, and the values can be tailored using designed porosity. The dielectric performance was found to be excellent and stable even at very high-frequency regimes (beyond 5G) between 70–90 GHz. Further, the addition of metallic infills in the designed pores of the ceramic scaffolds resulted in an increase in permittivity values. The preliminary investigation exhibited the potential to fabricate ceramic components for high-frequency applications via the design freedom offered by AM, that can enable further miniaturization of future communication devices.
Visual Servo Based Trajectory Planning for Fast and Accurate Sheet Pick and Place Operations
Authors: Manyar Omey M. , Kanyuck Alec , Deshkulkarni Bharat , Gupta Satyandra K. 
Published: September 2022

Abstract
In industry, several operations require sheet-like materials to be transported from a loading station to the desired location. Such applications are prevalent in the aerospace and textile industry where composite prepreg sheets or fabrics are placed over a tool or fed to a machine. Using robots for sheet transport operations offers a flexible solution for such highly complex tasks. To create high-quality parts, sheets need to be accurately placed at the correct location. This paper presents automated trajectory planning and control algorithms for a robot to pick up sheets from the input station using suction grippers and, transport and place them over the tool surface. Machine vision is used at the pick location for estimating the sheet pose. Unfortunately, pick-up accuracy is not sufficiently high due to sheet movement during suction-based grasping and localization errors. We employ ideas inspired by visual servo techniques to accurately place the sheet on the tool. Our method uses an Eye-to-Hand camera configuration to align the desired image features with the reference markings on the tool. We introduce a sampling-based Jacobian estimation scheme that can reliably achieve the desired accuracy while minimizing the operation time. Experiments are performed to validate our methodology and compute the placement accuracy on an industrial tool.
Stereotactic body radiotherapy (SBRT) versus androgen deprivation therapy (ADT) for oligometastatic prostate cancer: protocol for a prospective randomised control clinical trial
Authors: Zhao Xianzhi , Wang Tao , Ye Yusheng , Li Jing , Gao Xu , Zhang Huojun 
Published: September 2022

IntroductionThe systemic therapy, especially androgen deprivation therapy (ADT), is currently recommended for patients with oligometastatic prostate cancer (PCa). However, the results have not been satisfactory including adverse reactions and castration resistance. Therefore, it is necessary to explore more effective treatment to prolong biochemical progression-free survival (bPFS) and delay the start of hormonal therapy for treating oligometastatic PCa. Stereotactic body radiotherapy (SBRT) is an emerging treatment alternative for patients with oligometastases with high local control rates and minimal toxic effects. This prospective trial aims to demonstrate whether SBRT for the oligometastases of hormone-sensitive PCa can delay the start of ADT and prolong the time from inception of the study to castration-resistant prostate cancer (CRPC).Methods and analysisPatients with ≤3 oligometastatic recurrences, diagnosed on Ga-68 prostate-specific membrane antigen PET/CT, will be randomised in a 1:1 ratio between arm A (ADT only) and arm B (SBRT for oligometastases only). SBRT is conducted by CyberKnife with prescription dose 30–50 Gy in 3–5 fractions. One of the primary endpoints is ADT-free survival of arm B, the other is the time from inception of the study to CRPC. The secondary endpoints include radiotherapy-related toxicity, ADT-related toxicity, bPFS, local PFS and overall survival. Toxicity will be assessed using the National Cancer Institute Common Toxicity Criteria V.5.0.Ethics and disseminationThis protocol was approved by the institutional review board of Shanghai Changhai Hospital (CHEC2020-101). This is a randomised control clinical trial comparing SBRT to ADT for men with oligometastatic PCa. The study will be performed in compliance with applicable local legislation and in accordance with the ethical principles developed by the World Medical Association in the Declaration of Helsinki 2013. Study results will be disseminated through conferences and peer-reviewed scientific journals.Trial registration numberClinicaltrials.gov identifier:NCT04599686.
Significance of diagnosis and prognosis for appendiceal orifice inflammation in ulcerative colitis: a real-world study
Authors: Deng Peng , Yao Peng , Pei Chao , Li Xiao , Wu Junchao , Zhang Shu 
Published: September 2022

ObjectiveUlcerative colitis (UC) is a chronic inflammatory disease of the large intestine. At present, the significance of appendiceal orifice inflammation (AOI) in UC prognosis is still controversial. This prospective observational study investigated the importance of AOI in UC diagnosis and prognosis. Additionally, it compared the therapeutic efficacy of treatments in UC patients with or without AOI.DesignThis study was a prospective, observational, single-centre, real-world study. Patients with AOI were included in the observation group, and patients without AOI were assigned to the control group. All patients were followed up for 1 year; the disease remission and treatment efficacy were re-examined by colonoscopy. In addition, the clinical, endoscopic and pathological features were collected before and after the treatment.ResultsPatients with endoscopic diffuse inflammatory changes in the distal colorectum accompanied by AOI had a higher positive UC diagnosis rate than those without (96.5% vs 78.0%). Also, AOI had a specificity of 95.2% and a sensitivity of 28.3% for UC diagnosis. However, no difference in the modified Mayo score (p=0.881) or Baron grading was observed between the control and observation groups, indicating that AOI does not affect the treatment outcome of UC patients.ConclusionIn this study, the observation of AOI improved the UC diagnostic accuracy in patients with diffuse lesions in the distal colorectum. Furthermore, the presence of AOI does not affect the treatment efficacies of UC.Trial registration numberChiCTR1800017753.
Evaluating an oral health programme for the prevention of dental decay among school-aged children in China: protocol for a mixed-methods study based on the RE-AIM framework
Authors: Wang Lidan , Liu Hueiming , Wang Li , Zhang Yanqun , Guo Wei , Wu Peilin , Chang Xiangxiang , Wang Li , Xu Wenhua , Zhao Linhai 
Published: September 2022

IntroductionThe objective of the Comprehensive Intervention of Oral Disease for Children (CIODC) in China is to prevent dental decay for school-aged children and provide free prevention services in pilot areas beginning in 2008. It is a potentially affordable, acceptable and effective prevention strategy to use for more school-aged children in the future. There is a shortage of robust evidence regarding the cost-effectiveness, feasibility and scalability of prevention strategies for dental decay for school-aged children in China. This study aims to provide a comprehensive evaluation, including an economic evaluation and process evaluation, to better understand how and why the public health programme may be effective and economical.Methods and analysisMixed methods will be used in this study. Cost-effectiveness analysis (CEA) will be conducted from a societal perspective, based on a modelling study over 6 years (from age 7 to 12) in terms of the incremental cost-effectiveness ratios per dental decay averted. The Reach, Effectiveness, Adoption, Implementation, and Maintenance (RE-AIM) framework informed the process evaluation. An estimated 48–80 semistructured interviews with service providers, patient parents/caregivers and decision-makers under the logic model will be used in the progress evaluation to describe the feasibility and sustainability of CIODC.Ethics and disseminationThe study has all necessary ethical approvals from the Ethics Committee of Anhui Medical University (number 2021H030). All participants will provide informed consent prior to participation. Findings will be disseminated through conference presentations and scientific publications in peer-reviewed journals.
Screening and management of sleep disorders in patients with fibromyalgia syndrome: a French multicentred, prospective, observational study protocol (FIBOBS)
Authors: Andre Gilbert , Petitjean Pauline , Haas Victoria , Geraud Eva , Fantini Maria Livia , Creac'h Christelle , Perez Christèle , Bonnefoi Marlène , Gadea Emilie 
Published: September 2022

IntroductionSleep disorders are still often underestimated in patient care management even though they are present in the criteria of the American College of Rheumatology for the diagnosis of fibromyalgia syndrome (FMS). The objective of this study will be to assess the current situation of sleep disorders in patients with FMS in France and to estimate its prevalence.Methods and analysisThe FIBOBS study is a multicentred, prospective, observational trial performed by 46 specialised chronic pain structures in France. Patients with FMS visiting for a first consultation or follow-up (if they have already been followed up for less than a year with a pain management service) will be included after giving their informed consent. Data will be collected through the physician questionnaire filled during the inclusion visit. Patient self-questionnaires will be completed from home. The primary outcome of the study will be to estimate the prevalence of sleep disorders classified into three categories: (a) poor sleep quality in general, (b) sleep apnoea syndrome and (c) restless legs syndrome, using self-administered questionnaires.Ethics and disseminationThis protocol is approved by the ethics committee Comité de Protection des Personnes ‘Ile de France II’ in accordance with French regulations. The results will be disseminated through peer-reviewed journals and conferences.Trial registration numberNCT04775368.
Leading COVID-19 vaccination centres in England: managing and overcoming challenges
Authors: Jee Samuel David 
Published: September 2022

BackgroundThis study explored the challenges, and actions leaders took to manage them, in delivering the COVID-19 vaccine in vaccination centres in England.MethodsFollowing informed consent, 20 semi-structured interviews were conducted with 22 senior leaders working within vaccination centres, mostly clinical and operational leads, using Microsoft Teams. Transcripts were analysed thematically using ‘template analysis’.ResultsSome of the challenges leaders faced included leading dynamic and transient teams, interpreting and sharing communications received through national and regional and system vaccination operations centres. The simpler nature of the service allowed for leaders to delegate and reduce hierarchies among staff to support a more cohesive work environment that encouraged staff, often working through bank or agency, to return. Many leaders felt communication skills as well as the attributes of resilience and adaptability were particularly important to lead in these novel settings.ConclusionIllustrating the types of challenges faced by leaders in vaccination centres and how they handled them can help others in similar leadership positions in vaccine centres or other novel settings. As healthcare teams are increasingly dynamic and transient due to more flexible working patterns the need for leaders to apply these skills becomes ever more important.
A low-threshold diamond cryogenic detector for sub-GeV dark matter searches
Authors: Abdelhameed A. H. , Angloher G. , Bento A. , Bertoldo E. , Bertolini A. , Canonica L. , Iachellini N. Ferreiro , Fuchs D. , Garai A. , Hauff D. , Nilima A. , Mancuso M. , Petricca F. , Pröbst F. , Pucci F. , Rothe J. 
Published: September 2022

AbstractIn this work we report the realization of the first low-threshold cryogenic detector that uses diamond as absorber for astroparticle physics applications. We tested two 0.175 g CVD diamond samples, each instrumented with a W-TES. The sensors showed transitions at about 25 mK. We present the performance of the diamond detectors and we highlight the best performing one, where we obtained an energy threshold as low as 16.8 eV. This promising result lays the foundation for the use of diamond for different fields of applications where low threshold and excellent energy resolution are required, as i.e. light dark matter searches and BSM physics with coherent elastic neutrino nucleus scattering.
National Trends of Interhospital Transfers for Aneurysmal Subarachnoid Hemorrhage in the United States
Authors: Shah Dhaivat , Patel Urvish , Kellner Christopher , Bederson Joshua , Liang John , Dangayach Neha S 
Published: September 2022

Background
The American Heart Association guidelines recommend transferring patients with aneurysmal subarachnoid hemorrhage (aSAH) to high‐volume centers. The purpose of this study was to describe national trends in interhospital transfers (IHTs) for patients with aSAH in the United States.

Methods

We performed a cross‐sectional analysis of Nationwide Inpatient Sample (2008–2014) in adults hospitalized for aSAH. We performed weighted analyses using the χ
2
test, Student t‐test, and Cochran‐Armitage trend test. Multivariate survey logistic regression analysis with weighted algorithm modeling was performed to evaluate in‐hospital mortality and discharge disposition.

Results

Of 146 461 aSAH hospitalizations, 53 289 (36.38%) patients underwent IHT and 93 172 (63.62%) patients did not. There was a significant increase in the prevalence of IHT for aSAH (31.66% in 2008 to 39.91% in 2014;
P
‐trend<0.0001). Patients with aSAH who underwent IHT were younger (57 versus 59 years) and were more often women (62.71% versus 61.35%), White race (70.65% versus 63.93%), and private insurance holders (39.62% versus 36.14%) compared with patients with aSAH who did not undergo IHT (
P
<0.0001). Comparing aSAH sources of admission, more patients with aSAH at large hospitals (82.68% versus 75.14%) and urban teaching hospitals (90.43% versus 71.44%) had undergone IHT (
P
<0.0001). The patients with aSAH with IHT had lower prevalence and odds of all‐cause in‐hospital mortality (15.49% versus 20.12%; adjusted odds ratio, 0.85 [95% CI, 0.79–0.91]), longer length of stay (14 versus 11 days), and higher hospitalization costs ($213 852 versus $170 834) compared with patients without IHT (
P
<0.0001). The discharge disposition was not different among the 2 groups.

Conclusions
IHT has been steadily increasing for patients with aSAH over the past few years in the United States. IHT has been associated with lower odds of in‐hospital mortality, despite higher in‐hospital costs, longer length of stay, and unchanged discharge disposition in this patient population. Future studies should explore the different reasons for IHT and the prevalence of neurological deterioration during IHT.
Arch and Great Vessel Geometry From a Transradial Angiographic Approach
Authors: Zerebiec Katherine W. , Heidari Parisa , D'Agostino Erin , Soares Bruno P. , Johnson David M. , Raymond Scott B. 
Published: September 2022

Background
Neuroendovascular practices are transitioning from transfemoral to a radial‐first approach for cerebral angiography. Developing radial‐specific devices requires a comprehensive understanding of vessel size and geometry encountered from a right radial approach. We developed a database of aortic arch and vessel measurements relevant for radial‐specific device development.

Methods
The database contained 100 consecutive neck computed tomographic angiograms conducted on a 256‐slice emergency department computed tomographic scanner. Arch characteristics and measurements obtained from 1‐cm maximum intensity projection reformats included arch type and diameter, bifurcation angles, and distances from the arch to vessel origins. Statistical analysis was conducted using Excel and R.

Results
The database contained 56 female and 44 male patients; the average age was 62 years. A total of 46% had type 2 or 3 arch configuration, 19% had bovine configuration, and 5% had a left vertebral artery originating directly from the arch. Median angles at the arch from the innominate ranged from 20° to 47° and at branch vessels from 16° to 63° with large variation. The left carotid bifurcation was ≈8 cm further than the right carotid bifurcation. The left vertebral artery origin was median 3.8 cm from the arch.

Conclusions
We cataloged aortic arch and vessel geometries that have implications for catheter and device performance from a transradial approach. For example, a standard guide catheter that is adequate length for the right anterior circulation must be at least 8 cm longer for comparable distal support on the left because of the difference in distance from the right to the left. Catheter tip shape may be further optimized to improve vessel selection. Currently used catheters make a reverse curve angle of ≈15°, although most great vessels are at between 15° and 45°. Finally, the length of the distal arm of reverse curve catheters is just >4 cm, frequently inadequate to easily reach the left vertebral artery origin (median distance, 3.8 cm in this study). Transradial devices should be developed with these constraints in mind. This database provides benchmarks for future catheter design.
Determining the Location of the 22 May 1855 Chicago Area Tornado
Authors: Lincoln W. Scott , Ogorek Rafal , Borchardt Brett , Heraty Siobhan 
Published: September 2022

Abstract
The number and location of tornadoes in the greater Chicago area is a topic of frequent interest among the media, public, and local government agencies served by the National Weather Service (NWS) Chicago Forecast Office. While accounts of tornadoes over the last several decades are generally clear, tornadoes occurring prior to 1950—especially those considered to be weak—are often more difficult to discern owing to limited corresponding detailed reports. As part of an effort to review and update all tornadoes known to have occurred within the modern-day boundaries of Chicago, NWS Chicago staff reviewed the 22 May 1855 tornado, which is regarded as the first to impact the city of Chicago. Multiple sources reported that the tornado occurred near the town of Jefferson, which eventually became the Jefferson Park neighborhood of Chicago. However, after reviewing multiple historical records, newspaper articles, property maps, and genealogical information, the actual location of the tornado was determined to have been in present-day Des Plaines. Confusion over the name “Jefferson” likely led to the misunderstanding that, until now, has been perpetuated through numerous reports and media accounts.