bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effective control of Johne’s disease in large Czech dairy herds
Authors: Fichtelová Věra , Králová Alena , Babák Vladimír , Kovařčík Kamil 
Published: February 2022

Abstract

Introduction
Johne’s disease, caused by infection with Mycobacterium avium subsp. paratuberculosis (MAP), causes economic losses in dairy herds due to reduced milk production and premature culling. A test-and-cull strategy coupled with changes in calf rearing management preventing new infections has been introduced into infected herds to control MAP prevalence. This study appraised the effectiveness of these practice changes.

Material and Methods
In 19 large dairy herds (of a median 470 milk-producing cows), implementing MAP control measures for 3–7 years, a serum ELISA was used to detect infected cows in their dry-off period. The number of ELISA-positive animals per year (EPAY) was calculated and statistical analysis was used to test whether the EPAY total decreased during the control period and to analyse the EPAY in relationship to the duration of the control programme.

Results
Statistical support was found for a decrease of EPAY over time (P < 0.01, odds ratio 0.756) and in 14 herds a significant fall in the percentages of EPAY during the test period (P ≤ 0.05) was noted.

Conclusion
Our results demonstrated the effectiveness of the control measures in place to reduce MAP infection in herds with initial EPAY ≥3.36%. The missing decreasing trend in the remaining five herds with low average initial EPAY suggested the need for additional measures to reduce the number of infected animals in these herds.
Application of Landscape Metrics and Object-Oriented Remote Sensing to Detect the Spatial Arrangement of Agricultural Land
Authors: Safdary Rezvan , Soffianian Alireza , Pourmanafi Saeid 
Published: February 2022

AbstractThis study aims to investigate crop selection and spatial patterns of agricultural fields in a drought-affected region in Isfahan Province, central Iran. Based on field surveys portraying growth stages of the main crops including wheat, alfalfa, vegetables and fruit trees, three Landsat 8 operational land imager (OLI) images were acquired on March 15 (L1), June 27 (L2) and October 1 (L3), 2015. After performing radiometric and atmospheric corrections, Normalized Difference Vegetation Index (NDVI) maps of the images were produced and introduced to the Multi-Resolution Segmentation algorithm to delineate agricultural fields. An NDVI-based decision algorithm was then developed to identify crops devoted to each field. Finally, a set of landscape metrics including Number of Patches (NP), mean patch size (MPS), mean shape index (MSI), perimeter-to-area ratio (PARA) and Euclidian Nearest Neighborhood Distance (ENN) was utilized to evaluate their respective spatial formation. The results showed that nearly 46% of fields are devoted to wheat indicating that the landscape has been dramatically shifted towards wheat monoculture farming. Moreover, the farmers’ inclination to grow crops in large fields (approximate area of 1 ha) with more regular geometric shapes are considered as an effective way of optimising water use efficiency in areas experiencing significant water shortage.
Hubungan Indeks Massa Tubuh dan Lingkar Pinggang dengan Kualitas Tidur Mahasiswa Preklinik Program Studi Kedokteran, Fakultas Kedokteran Universitas Mulawarman
Authors: Sari Rohmi Pawitra , Rotinsulu Denny Jeffry , Fitriany Evi 
Published: February 2022

Sleep is defined as unconsciousness from which the person can be aroused by sensory or other stimuli. Long-term consequences of sleep deprivation increased the risk of hypertension, diabetes mellitus, obesity, heart failure, stroke, memory impairment as well as depression. Obesity is one of the factors that affect sleep quality. Obesity is associated with sleep quality through its effect of causing obstructive sleep apneu (OSA), increased proinflammatory cytokins and gastrointestinal disorders. This study aims to analyze the correlation between body mass index and waist circumference with the quality of sleep of the pre-clinical students of the Mulawarman University, Faculty of Medicine. This research is an observational analytic study with a cross-sectional approach. Sleep quality data were collected using the PSQI questionare while body mass index and waist circumference data were collected by measuring body height using microtoise, body weight using a weighing scale and waist circumference using an anthropometric band. The result showed that 81.2% of respondents had poor sleep quality, 28.2% of respondents with obesity category and 35.9% of respondents who had central obesity. The result of hypothesis testing using chi square showed that both body mass index and waist curcumference had a significant relationship with sleep quality (p=0.046 and p=0.027).
Validasi Metode Penetapan Kadar Boraks pada Kerupuk Puli Menggunakan Spektrofotometer UV-Vis
Authors: Anngela Oppie , Muadifah Afidatul , Nugraha Dhanang Prawira 
Published: February 2022

Rice cracker or known as Krupuk puli is the kind of deep-fried crackers in Indonesia that made of rice seasoned with spices and flavor enhancer. Most Rice cracker sellers that peddle their products in the Ngunut traditional market, so that the sellers have to make or prepare the rice cracker as well as possible to make the cracker can be sold. In this case, most manufacturers add hazardous materials (borax) in the process of making rice crackers. The purpose of this research is to validate the method and to know the borax level of rice crackers sold in the Ngunut traditional market by using the UV-Vis spectrophotometry method. Optimization of borax wavelength in the wavelength range of 500-600 nm. The prepared samples are analyzed using UV-Vis spectrophotometry at the maximum wavelength that is 506 nm. The next step, is, validation methods, including linieritas test, accuracy test, precision test, and LOD test & LOQ. The result of this study obtained the optimum wavelength is 506 nm. Based on the validation methods that have been done, obtained the results of inference linearity in the concentration range of 5ppm; 20ppm; 35ppm; 50ppm; 65ppm with a physical value of R2 correlation of 0.993,%recovery by 96.5%, the precision value obtained by 0.375%, and the LOD value of 48.565 ppm amounting and a Loq value of 161.381 ppm. The borax level in sample A amounted to 1,380 ± 1.824 ppm, sample B of 852.1 ± 2.367 ppm, sample C of 1,373 ± 1.824 ppm, and sample D of 185.9 ± 1.788 ppm.
Analysis of Platelet Count on Liver Cirrhosis Patients Based on Child-Pugh Classification
Authors: Maulidya Fadyla Renanda , Bakhtiar Rahmat , Murti RR. Ignatia Sinta 
Published: February 2022

Liver cirrhosis is described as a diffused pathological process which marked with fibrosis and architectural changes of normal liver that becomes an abnormal nodular structure. Liver cirrhosis is caused by chronic liver disease of virus nor non virus. Thrombocytopenia is a hematology abnormality which frequently found on liver cirrhosis patients. Severity level and prognosis of liver cirrhosis can be determined by Child-Pugh classification. This research aims to know the difference of mean platelet count on liver cirrhosis patients based on Child-Pugh classification. It applied analytic observational method with cross-sectional design. The data was taken from medical records of patients at Abdul Wahab Sjahranie Hospital in Samarinda of 2018-2020 period. Statistical analysis was using Kruskal-Wallis test. The results showed liver cirrhosis patients in Child-Pugh C is at most. Mean platelet count of liver cirrhosis with Child-Pugh A is 73.250/?l, Child-Pugh B is 126.370/?l, and Child-Pugh C is 148.375/ ?l. Based on statistical test, the score p = 0,19 (p > 0,05), there are no differences of mean platelet count among the three Child-Pugh classifications.
Efikasi dan Keamanan dari Pancreatic Enzyme Replacement Therapy pada Pasien Cystic Fibrosis : Sebuah Kajian Sistematis
Authors: Suastini Ni Made , Herawati Fauna 
Published: February 2022

ABSTRAK
Sekitar 80-90% pasien cystic fibrosis akan mengalami pancreatic insuffiency. Keadaan ini akan menyebabkan terjadinya malabsorpsi lemak dan protein dan akan berpengaruh pada status nutrisi dari pasien. Terapi dari terjadinya pancreatic insufficiency ini adalah dengan pemberian pancreatic enzyme replacement therapy (PERT) untuk meningkatkan absorpsi dari lemak dan juga protein pada pasien cystic fibrosis. Tujuan dari kajian sistematis ini adalah untuk mengetahui efikasi dan keamanan dari pemberian terapi PERT pada pasien yang mengalami pancreatic insufficiency pada pasien cystic fibrosis sehingga dapat dijadikan acuan atau pedoman dalam pemberian terapi PERT. Proses penelusuran pustaka melalui PUBMED dan Cohcrane Library menggunakan kata kunci PERT dan Cystic Fibrosis dengan Boolean operator “AND”. Penelitian yang terpilih sebanyak 14 dengan kriteria berupa RCT, pasien segala usia, pasien cystic fibrosis dengan pancreatic insufficiency, dan membandingkan PERT dengan plasebo atau formulasi lain. Dari empat belas penelitian semua studi memperlihatkan peningkatan % CFA dari pemberian terapi PERT. Peningkatan % CFA dari semua studi mencapai rentang > 60% sampai > 80%. Studi yang membandingkan sediaan PERT dengan plasebo menunjukan hasil bahwa PERT mampu meningkatankan % CFA menjadi > 70% sementara plasebo memiliki % CFA sekitar 40% dan pemberian terapi PERT dinilai relatif aman dan dapat ditoleransi oleh pasien dengan cystic fibrosis.
ABSTRACT
Approximately 80-90% patients with cystic fibrosis will experience pancreatic insufficiency. This condition will cause the malabsorption of fats and proteins and will affect the nutritional status of the patients. Therapy of pancreatic insufficiency is by administering of pancreatic enzyme replacement therapy (PERT) to increase absorption of fat and protein in patients with cystic fibrosis. This systematic review aimed determine the efficacy and safety of the administration of PERT in patients who experience pancreatic insufficiency with cystic fibrosis, and this systematic review can be used as reference or guideline in the administration of PERT. The search strategy was undertaken using PUBMED and Cochrane Library, and the search term were “PERT” and “Cystic Fibrosis” wich were combines with the use of Boolean operator “AND”. In total, 14 studies were include in the final review with criteria is RCT, patients of any age, patients with cystic fibrosis and pancreatic insufficiency, and compared to placebo or other formulations. All studies showed an increase in the % CFA from administration of PERT. the increase of % CFA from all studies reached a range of > 60% to > 80%. Studies comparing PERT and placebo showed that PERT was able to increase of % CFA to > 70% while placebo had % CFA about 40% and PERT therapy was considered relatively safe and well tolerated by patients with cystic fibrosis.
Skrening Kandungan Kimia Macaranga gigantea Reichb.f. & Zoll Interaksi terhadap GSTs
Authors: Hadi Samsul , Nastiti Kunti , Ekowati Dian , Muliana Ana , Subekti Arif 
Published: February 2022

Penelitian Macaranga gigantea sebagai antioksidan sudah banyak dilakukan, Metode yang dipakai yaitu penangkap radikal DPPH dan Lipidperoksidasi. Metode isolasi senyawa dari Macaranga gigantea juga sudah dilakukan dan menghasilkan berbagai macam kandungan. Sehingga penelitian ini bertujuan mencari senyawa yang mempunyai interaksi paling stabil terhadap reseptor GSTs, karena GSTs adalah salah satu enzim yang berperan dalam antioksidan secara alami di dalam tubuh. Metode yang digunkan dalam penelitian ini adalah docking dengan metode PLANTS, persiapan ligand dengan Marvin Beans, dan visualisasi dengan Discovery studio. Dari penelitian ini diperoleh skor docking yang lebih baik dari ligand original pada 1TDI yaitu corilagin (-94,764), glyasperin A (-86,784), macagigantin (-104,752), musennin (-82,217), skor docking yang terbaik ketika berikatan dengan 3LJR adalah macagigantin (-110,028) dan dengan 18GS adalah macagigantin (-83,675). Kesimpulan dari penelitian ini adalah macagigantin dari Macaranga gigantea merupakan ligand potensial dalam hal stabilasi interaksi dengan reseptor.
Analisis Finansial Usaha Peternakan Itik Petelur dengan Sistem Pemeliharaan Intensif di Kecamatan Gadingrejo Kabupaten Pringsewu
Authors: Sari Yuni Hidayah , Endaryanto Teguh , Murniati Ktut 
Published: February 2022

This study aims to analyze the financial and sensitivity of the intensive system maintenance laying duck business in Gadingrejo Subdistrict of Pringsewu District. The location was chosen purposively in Gadingrejo Subdistrict, considering that the location is a duck center in Pringsewu.Â Data was collected in February 2019.Â Respondents were taken by census method with a total of 15 breeders.Â They were divided into six categories based on business experience, namely breeders with business experience of two years, four years, five years, six years, eight years and more than 10 years.Â The results showed that the laying duck business with intensive system maintenance in six categories was profitable and feasible to be developed based on investment criteria (Internal Rate Return (IRR), Net Present Value (NPV), Net Benefit Cost Ratio (Net B/C), Gross Benefit Cost (Gross B/C), and Payback Period (PP)).Â The laying duck business was Â sensitive to decreas egg price and decreas production.Â Whereas the increase in production costs and the concentrate feed prices are only sensitive to the Payback Period investment criteria indicator.Â Keywords : duck breeder, financial, sensitivity
ANALISIS POLA PEMBELIAN PRODUK PADA E-COMMERCE PANENMART
Authors: Husain Tsalis Kurniawan , Amran Farizah Dhaifina 
Published: February 2022

Tujuan penelitian ini adalah untuk mengetahui dan menganalisis pola pembelian produk pada e-commerce Panenmart. Metode dasar yang digunakan adalah metode eksperimen. Teknik pengambilan sampel pada penelitian ini adalah sampling jenuh (sensus). Data yang digunakan dalam penelitian bersumber dari data sekunder yang diperoleh dari data transaksi belanja yang didapatkan melalui database transaksi penjualan website dan aplikasi mobile Panenmart. Untuk mengetahui pola aturan asosiasi pembelian produk maka digunakan Market Basket Analysis (MBA) berdasarkan tiga metrik, yaitu support, confidence dan lift ratio. Pada penelitian ini menggunakan nilai minimum support 0,1 dan nilai minimum confidence 0,3. Hasil penelitian menunjukkan 3 pola aturan asosiasi pembelian produk yang memiliki hubungan yang kuat dan valid dibeli secara bersamaan karena memiliki nilai confidence lebih dari 0,3 dan nilai lift ratio > 1. Adapun itemset produk yang memiliki pola aturan yaitu, cabe rawit dan buncis; jagung dan bayam; bayam dan buncis.
KERAGAAN DAN PENGEMBANGAN AGRIBISNIS KOPI ROBUSTA DI PROVINSI LAMPUNG (Studi Kasus : Kab Tanggamus)
Authors: Darwis Valeriana , Saputra Yonas Hangga , Muslim Chairul 
Published: February 2022

Provinsi Lampung merupakan salah satu sentra agribisnis kopi Robusta yang masuk lokasi pengembangan kawasan kopi yang terdapat dalam Keputusan Menteri Pertanian Nomor 472 Tahun 2018. Berdasarkan penetapan itu maka tulisan ini bertujuan untuk mengetahui sistem produksi, biaya pemeliharaan dan rantai pasok di Provinsi Lampung. Survay dilaksanakan bulan Juli tahun 2019 dengan metoda pengumpulan data melalui FGD dan wawancara langsung dengan petani mempergunakan kuesioner. Dari hasil analisis deskriptif kualitatif dan harga pokok pemeliharaan ditemukan bahwa agribisnis kopi Robusta di Provinsi Lampung mengalami pertumbuhan positif. Hal ini direpresentasikan dari peningkatan harga jual kopiÂ sebesar 0,39%/tahun, luas tanam 0,33%/tahun dan produksi 0,09%/tahun. Tetapi dari segi produktivitas petani responden hanya menghasilkan 593 kg/tahun atau masih rendah dibandingkan produktivitas nasional sebesar 656 kg/tahun dan produktivitas provinsi Lampung sebesar 800 kg/tahun.Â Rendahnya produktivitas petani responden disebabkan oleh: (i) kurang motivasi memelihara karena biaya pemeliharaan perkg (Rp 4.013) lebih rendah dibandingkan harga jual kopi (Rp 18.000) ; (ii) usia tanaman sudah tua dan (iii) bukan merupakan tanaman utama. Agribisnis kopi di Provinsi Lampung masih bisa ditingkatkan lagi dengan cara: (i) meningkatkan produktivitas melalui penerapan budidaya berdasar GAP kopi ; (ii) membuat demplot dilokasi petani sebagai upaya dalam mensosialisasikan hasil penelitian dari Litbang Kementan ; (iii) membangun kembali kelembagaan khususnya dalam mengatasi masalah produksi, pemasaran dan pengolahan hasil sertaÂ (iv) membuat kemitraan dengan pedagang atau roastery sehingga petani tidak perlu lagi menjual dalam bentuk biji asalan.Â Kata Kunci : agribisnis dan kopi robusta
Trending topics in orthodontic treatment practices in the past 5 years: A longitudinal study on case reports
Authors: Ozturk Taner , Coban Gokhan 
Published: February 2022

Objectives:
This study aimed to analyze the case reports published in the past 5 years in orthodontic journals in the Web of Science (WOS) indexes and evaluate the trending topics.

Material and Methods:
Following a search conducted by entering the keyword “orthodontics” in the WOS Master Journal List search site, four journals in the Science Citation Index (SCI) and five journals in the Emerging Science Citation Index (ESCI) were included in the study, and case report articles published in these journals between 2016 and 2020 were examined. The case reports were analyzed by examining each issue of each journal published during these years. In addition, frequently studied topics were examined under seven headings.

Results:
Only nine of the 16 journals in the list of related journals have published case reports in the past 5 years. The largest number of articles appeared in the American Journal of Orthodontics and Dentofacial Orthopedics for the SCI group and International Orthodontics for the ESCI group. When the frequently examined topics were evaluated, it was determined that the highest number of articles was fixed orthodontic treatments (53.4%), orthognathic surgery (18.9%), multidisciplinary treatments (6.5%), and treatments for individuals with general health problems (6.5%).

Conclusion:
The number of case reports published has gradually increased in the past 5 years. The number of articles in the journals included in the SCI is higher. The subject variety of case reports is too great to be limited to a narrow field.
Post-operative clinical outcomes and complications of posterior versus lateral approach for primary total hip arthroplasty: A retrospective cohort study
Authors: Halawani Alhussain K. , Ghaddaf Abdullah A. , Alomari Mohammed S. , Alaryani Khalid H. , Alibrahim Abdulrahman O. , Alshehri Mohammed S. 
Published: February 2022

Objectives:
Total hip arthroplasty (THA) is considered one of the therapeutic procedures frequently performed in orthopedic surgery. It is believed that the surgical approach could influence the clinical outcomes following THA. We performed a retrospective cohort study to compare the postoperative clinical outcomes and complications between the posterior approach (PA) and the lateral approach (LA) for primary THA.

Methods:
We enrolled patients who underwent primary THA through PA or LA. We sought to evaluate the postoperative complications including the need for intra- or postoperative blood transfusion, dislocation rate, and venous thromboembolism events, and the clinical outcomes, including length of hospital stay, operative time, and perioperative blood loss.

Results:
A total of 211 patients (71 patients in PA vs. 140 patients in LA) were deemed eligible to be included in this study. There was no significant difference between PA and LA in post-operative clinical outcomes concerning operative time, and perioperative blood loss except for the length of hospital stay (PA median = 6.0 days vs. LA median = 9.0 days; P < 0.001) patients. After adjustment for the potential confounders, the length of hospital stay was found to be similar between the two groups (P = 0.06). Similarly, no difference was found between PA and LA in post-operative complications concerning the need for intra-operative blood transfusion, dislocation rate, and venous thromboembolism events except for the need for postoperative blood transfusion (RR = 1.82, 95% CI 1.16–2.87), which continued to be significantly higher in PA even after adjustment for the potential confounders (P ≤ 0.01).

Conclusion:
PA and LA herald similar outcomes for patients undergoing primary THA concerning the postoperative clinical outcomes and complications except for the need for post-operative blood transfusion.
Spontaneous spinal epidural hematoma related to amphetamine abuse: A case report
Authors: Obaid Sami , Elkaim Lior M. , Gariepy Charles , Westwick Harrison J. , Yuh Sung-Joo , Shedid Daniel 
Published: February 2022

Background:
Spontaneous spinal epidural hematoma (SSEH) is a rare condition that is typically associated with hypertension, the use of antithrombotic or sympathomimetic drugs. Here, we report a case of SSEH attributed to the use of amphetamines.

Case Description:
A 27-year-old amphetamine user presented with the sudden onset of paraplegia (Frankel A) following amphetamine use. An MRI revealed C7–T2 spinal cord compression due to an epidural hematoma. Following a negative angiogram, the SSEH was removed, and the patient markedly recovered. Notably, by exclusion, the etiology for the SSEH was attributed to the use of amphetamines.

Conclusion:
Here, we demonstrate the case of a 27-year-old male who presented paraplegic due to an acute C7– T2 SSEH secondary to amphetamine abuse.
SEASONAL VARIATIONS IN THE DEFORMATION AND RADIO-THERMAL RADIATION OF THE ICE COVER OF LAKE ARACHLEY DURING THE PERIOD OF MAXIMUM DIFFERENCES OF DAILY TEMPERATURES
Authors: Венславский В.Б. , Орлов А.О. , Харин Ю.В. 
Published: February 2022

В 2020–21 гг. выполнены измерения радиояркостной температуры ледяного покрова озера Арахлей (Забайкальский край). Аппаратуру в составе 4 радиометров на длины волн от 0.3 до 2 см разместили на берегу озера на стационарную платформу. Одновременно измеряли температуру льда и деформацию ледяного покрова. Установлено, что мощность радиотеплового излучения и величина деформации ледяных полей коррелируют с данными температурного профиля по глубине ледяного покрова. Микроволновые характеристики могут быть геоиндикатором трещинообразования и сезонных проявлений метеорологических особенностей.
In 2020–21 measurements of the radio brightness temperature of the ice cover of Lake Arakhley (Trans-Baikal Territory) were carried out.The equipment, consisting of 4 radiometers for wavelengths from 0.3 to 2 cm, was installed on the shore of the lake on a stationary platform. The ice temperature and the deformation of the ice cover were measured at the same time. It was found that the power of radio-thermal radiation and deformation of ice fields correlate with the data of the temperature profile along the depth of the ice cover. Microwave characteristics can be a geo-indicator of fracture formation and seasonal manifestations of meteorological features.