bluuebunny/crossref_metadata_2025_split huggingface dataset:
The FASA model
Authors: Bellon Jacqueline , Eyssel Friederike , Gransche Bruno , Nähr-Wagener Sebastian , Wullenkord Ricarda 
Published: September 2022

AbstractPeople usually have the ability to ‘read the room’ and strike the ‘right tone’ in interaction situations. In most cases, they know what is considered (in)appropriate in specific situations. Moreover, even though the understanding of what is and is not socially appropriate in a certain situation varies among interaction participants, human beings have an outstanding ability to coordinate with one another very quickly and effectively repair any ‘breaks’ in communication that may have arisen. Within the FASA model we propose five factors and corresponding criteria that may influence what will be deemed socially appropriate or inappropriate.
Einfluss von Richtmikrofonie auf die Höranstrengung bei Mittelohrimplantatträgern
Authors: Hollfelder Daniela , Prein Lukas , Jürgens Tim , Leichtle Anke , Bruchhage Karl-Ludwig 
Published: September 2022

Zusammenfassung
Hintergrund und Ziel der Arbeit
Neben dem Sprachverstehen ist die empfundene Höranstrengung im Alltag ein wichtiger Indikator für den Erfolg einer Hörhilfe und deren Signalverarbeitung. Diese Studie hat zum Ziel, die subjektive Höranstrengung für Sprache im Störgeräusch bei Patienten mit dem aktiven Mittelohrimplantat Vibrant Soundbridge (VSB) für omnidirektionale und direktionale Richtwirkung und für einseitiges und beidseitiges Hören zu ermitteln.

Material und Methoden
Bei 15 VSB-Trägern wurde die subjektive Höranstrengung in einem Lautsprecherring im reflexionsarmen Raum mit der adaptiven Skalierungsmethode ACALES (Adaptive CAtegorical Listening Effort Scaling) erfasst. Verschiedene Hintergrund-Störgeräusche aus unterschiedlichen Richtungen und gleichzeitig dargebotene Sätze aus dem Oldenburger Satztest wurden zu vier alltagsnahen akustischen Szenen kombiniert.

Ergebnisse
Direktionale Richtwirkung verringerte die Höranstrengung bei VSB-Trägern im Median nur numerisch, insbesondere bei räumlich verteilten Störquellen und niedrigem Signal-Rausch-Verhältnis, allerdings ohne signifikanten Unterschied zur omnidirektionalen Einstellung. Einseitiges Hören mit VSB (bei Verschluss des kontralateralen Ohrs) führte dazu, dass im Probandenmittel alle untersuchten Höranstrengungskategorien bei signifikant höheren Signal-Rausch-Verhältnissen gemessen wurden als bei beidseitigem Hören.

Schlussfolgerung
Insgesamt konnte keine statistisch signifikant niedrigere Höranstrengung bei Verwendung des Richtmikrofonprogramms nachgewiesen werden, daher liefert diese Studie keine Empfehlung für oder gegen das Richtmikrofonprogramm. Allerdings konnte eine geringere Höranstrengung bei beidseitigem Hören im Gegensatz zu einseitigem Hören gezeigt werden. Patienten sollten daher ermutigt werden, immer mit beiden Ohren bestmöglich versorgt zu hören.
Hispanic Farmers Experience Shorter EMS Response Times but Longer Emergency Department Length of Stay Following Occupational Injuries
Authors: Young Chloe M. , Panjwani Suraj , Druar Nicholas , Cahan Mitchell A. 
Published: September 2022

AbstractBackgroundAgriculture has the highest rate of fatal injuries by sector. Hispanic workers also experience more fatal work injuries than every other minority group combined. Pre‐hospital and initial trauma evaluation represent an important marker to understand the impact of a trauma system. We sought to investigate whether Hispanic agricultural workers in the United States (US) experience disparities following traumatic occupational injuries in terms of pre‐hospital and emergency department care.MethodsWe retrospectively analyzed the National Trauma Data Bank from 2012–2016 to understand differences between Hispanic and non‐Hispanic farmers in Emergency Medical Services (EMS) response and transport times (minutes), transport mode, transfer rates, presentation to University or Level I trauma hospitals, Injury Severity Scores (ISS), length of stay (LOS) in the emergency department (ED, minutes) or hospital (days), need for the operating room (OR), admittance to the Intensive Care Unit (ICU), and mortality.ResultsA total of 6,161 farmers were included in our analyses (median age 47 years, females 7.0%). Multivariable analyses indicate differences regarding EMS response, EMS transport, and LOS in the ED. Rates of admission to the ICU, surgical operations, days on a ventilator, discharge from the hospital with supportive care, and mortality did not differ between groups.ConclusionsNon‐Hispanic patients have longer median EMS response and total transport times. Hispanic patients have longer median LOS in the ED. However, the lack of significant differences in management variables other than EMS times and ED LOS indicate an equitable delivery of trauma care once patients were transferred from the ED.
Analysis of the annual pollen integral in Albuquerque, New Mexico, shows a negative trend with temperatures for Juniper, Cottonwood, Elm, and Mulberry
Authors: Aprea Claudia M. , Torres David J. , Cordova Melany M. 
Published: September 2022

AbstractThe goal of this study is to determine if the annual pollen integral (APIn) for the top tree allergens in the City of Albuquerque is correlated with meteorological variables. This analysis would be the first of its kind for this area. We used 17 consecutive years from 2004 to 2020 and data collected by the city of Albuquerque using a Spore Trap (Burkard) volumetric air sampler in a location designed to represent a typical desert environment. The pollen studied include Juniper, Elm, Ash, Cottonwood, and Mulberry. We found a negative linear correlation with early summer temperatures of the previous year and APIn for Elm, Cottonwood, and Mulberry, and early fall temperatures for Juniper. Linear regression models developed for Elm, Cottonwood, and Mulberry used the monthly mean maximum temperature for the month of June of the prior year as the independent variable to yield a R squared statistic (R2) of 0.88, 0.91 and 0.78, respectively. For Juniper, the average monthly mean minimum temperature for the previous September and October served as the independent variable and yielded the R2 value of 0.80. We also observed a positive trend for the annual maximum temperature over time and a negative trend for the total APIn. Summers in New Mexico are hot and dry, and they may be getting hotter and drier because of climate change. Our analysis predicts that climate change in this area may lead to reduced allergies if temperatures continue to increase and if precipitation patterns remain the same.
High-yield production in Escherichia coli and convenient purification of a candidate vaccine against SARS-CoV-2
Authors: Maltoni Giulia , Scutteri Lorenzo , Mensitieri Francesca , Piaz Fabrizio Dal , Hochkoeppler Alejandro 
Published: September 2022

Abstract
Objectives
The aim of the present work was to identify a time-saving, effective, and low-cost strategy to produce in Escherichia coli a protein chimera representing a fusion anti-SARS-CoV-2 candidate vaccine, consisting of immunogenic and antigenic moieties.

Results
We overexpressed in E. coli BL21(DE3) a synthetic gene coding for CRM197-RBD, and the target protein was detected in inclusion bodies. CRM197-RBD was solubilized with 1 % (w/v) of the anionic detergent N-lauroylsarcosine (sarkosyl), the removal of which from the protein solution was conveniently accomplished with Amberlite XAD-4. The detergent-free CRM197-RBD was then separated from contaminating DNA using polyethylenimine (PEI), and finally purified from PEI by salting out with ammonium sulfate. Structural (CD spectrum) and functional (DNase activity) assays revealed that the CRM197-RBD chimera featured a native and active conformation. Remarkably, we determined a yield of purified CRM197-RBD equal to 23 mg per litre of culture.

Conclusions
To produce CRM197-RBD, we devised the use of sarkosyl as an alternative to urea to solubilize the target protein from E. coli inclusion bodies, and the easy removal of sarkosyl by means of Amberlite XAD-4.
The Ethics and Politics of Academic Knowledge Production: Thoughts on the Future of Business Ethics
Authors: Burrell Gibson , Hyman Michael R. , Michaelson Christopher , Nelson Julie A. , Taylor Scott , West Andrew 
Published: September 2022

AbstractTo commemorate 40 years since the founding of the Journal of Business Ethics, the editors in chief of the journal have invited the editors to provide commentaries on the future of business ethics. This essay comprises a selection of commentaries aimed at creating dialogue around the theme The Ethics and Politics of Academic Knowledge Production. Questions of who produces knowledge about what, and how that knowledge is produced, are inherent to editing and publishing academic journals. At the Journal of Business Ethics, we understand the ethical responsibility of academic knowledge production as going far beyond conventions around the integrity of the research content and research processes. We are deeply aware that access to resources, knowledge of the rules of the game, and being able to set those rules, are systematically and unequally distributed. One could ask the question “for whom is knowledge now ethical’”? (See the Burrell commentary.) We have a responsibility to address these inequalities and open up our journal to lesser heard voices, ideas, and ways of being. Our six commentators pursue this through various aspects of the ethics and politics of academic knowledge production. Working with MacIntyre’s scheme of practices and institutions, Andrew West provides commentary on the internal good of business ethics learning and education. Inviting us to step out of the cave, Christopher Michaelson urges a clear-eyed, unblinking focus on the purposes and audiences of business ethics scholarship. As developmental editor, Scott Taylor uncovers some of the politics of peer review with the aim of nurturing of unconventional research. Mike Hyman presents his idiosyncratic view of marketing ethics. In the penultimate commentary, Julie Nelson attributes difficulties in the academic positioning of the Business Ethics field to the hegemony of a masculine-centric model of the firm. And finally, Gibson Burrell provides a powerful provocation to go undercover as researcher-investigators in a parallel ethics of the research process.
Interventions Involving Caregivers for Children and Adolescents Following Traumatic Events: A Systematic Review and Meta-Analysis
Authors: Szota Katharina , Schulte Katharina Louisa , Christiansen Hanna 
Published: September 2022

AbstractAlthough treatment guidelines recommend interventions entailing caregiver involvement for children and adolescents following traumatic experiences, evidence on their effectiveness is inconsistent. The present systematic review and meta-analysis considered possible moderators of their effectiveness. Method. Eligible studies were (quasi-)randomized controlled trials and efficacy trials published in English or German with participants up to the age of 21 years presenting symptoms of mental disorders due to traumatic experiences. The effectiveness of interventions entailing any kind and extent of caregiver involvement had to be investigated by applying evaluated instruments. PubMed, PsycINFO, ERIC, COCHRANE and PSYNDEX were searched. Results. A total of 33 studies with 36 independent samples were retrieved. Child- and parent-reports on PTSD, depression, anxiety, ADHD, internalizing, externalizing symptoms and behavior problems were analyzed where available. The pooled effect size is significant and robust at post-treatment for child-reported PTSD, g = − 0.34 (95% CI = − 0.53; − 0.14), parent-reported PTSD, g = − 0.41 (95% CI = − 0.71; − 0.11), child-reported depression, g = − 0.29 (95% CI = − 0.46; − 0.11), child-reported anxiety, g = − 0.25 (95% CI = − 0.42; − 0.08), and parent-reported internalizing symptoms, g = − 0.27 (95% CI = − 0.47; − 0.07). Female sex and fulfilling diagnostic criteria appeared as potential moderators. The only significant effect size at follow-up is found for child-reported PTSD symptoms 12 months post-treatment, g = − 0.37 (95% CI = − 0.67; − 0.07). Conclusions. Interventions entailing caregiver involvement revealed greater symptom reductions than control conditions. Determinants of their effectiveness should be examined further.
Atypical Facial Expressivity in Young Children with Problematic Peer Relationships
Authors: Howe-Davies Holly , Manstead Antony S. R. , van Goozen Stephanie H. M. 
Published: September 2022

AbstractPeer problems are frequently associated with difficulties in recognizing and appraising the emotions of others. It has been argued that facial responsiveness to others’ emotions—or motor empathy—is a precursor of emotion processing and affective empathy. Although mimicry impairments have been observed in studies of young people with conduct problems, to our knowledge no study has examined facial responsiveness to others’ expressions in young children and examined how this relates to peer relationship problems. Four- to 7-year-old children (n = 91) with or without teacher-reported peer relationship problems (Strength and Difficulties Questionnaire) viewed three dynamic film clips depicting a sad, happy, or scared child, while their spontaneous facial emotional responses were assessed using iMotions software that codes the movement of facial muscles. Children displayed facial expressivity that was congruent with the emotional expressions in the clips. Groups with and without peer problems did not differ in their responses to seeing a happy child. However, children with peer problems exhibited reduced or atypical facial emotional responses to the negative emotional clips. Decreased or atypical facial expressivity to negative emotions was also associated with severity of peer problems; atypical facial responsivity to sadness and reduced facial responsivity to fear predicted peer problems independently of one another. We conclude that reduced or atypical facial expressiveness in response to other children’s dynamic facial expressions is associated with problematic peer relations in young children. The implications for early identification and interventions to support prosocial development are discussed.
Benefits and Limitations of the Growth Inversion Approach in Volcano Gravimetry Demonstrated on the Revisited 2004–2005 Tenerife Unrest
Authors: Vajda Peter , Camacho Antonio G. , Fernández José 
Published: September 2022

Abstract
We review the current geoscientific knowledge of the volcanic unrest of 2004–2005 on Tenerife (Canary Islands) and revisit its gravimetric imprint. We revise the interpretation of the observed spatiotemporal (time-lapse) gravity changes accompanying the unrest by applying the Growth inversion approach based on model exploration and free geometry growing source bodies. We interpret the Growth solution, our new gravimetric model of the unrest, in the context of structural controls and the existing volcanological and geological knowledge of the central volcanic complex (CVC) of the island. Structural controls are inferred from the updated structural subsurface CVC density model obtained by our new Growth inversion of the available complete Bouguer anomalies (CBA data). Our gravimetric picture sees the unrest as a failed eruption, due to a stalled magma intrusion in the central position below the Teide–Pico Viejo stratocones, followed by upward and lateral migration of volcanic fluids reaching the aquifer and the SW end of the caldera wall. We thus classify the volcanic unrest of 2004–2005 as hybrid, in agreement with previous studies. The Growth inversion indicates that magma propagated along the boundary between the basaltic core of the island, the Boca Tauce volcanic body and the more permeable (less compacted) volcanic rocks with lower density. This gravimetric picture of the unrest provides new insights into the potential future reactivation of the volcanic system.

Article Highlights

Current geoscientific knowledge of the Tenerife volcanic unrest of 2004–2005 is reviewed

New insights into the unrest are yielded by Growth inversion of observed time-lapse gravity changes

Role of the freely adjustable inversion parameters in the Growth methodology is demonstrated

Pros and cons of the Growth inversion approach in volcano gravimetric applications are illustrated
CMMSE: numerical analysis of a chemical targeting model
Authors: Baldonedo Jacobo , Fernández José R. , Segade Abraham , Suárez Sofía 
Published: September 2022

AbstractTreating specific tissues without affecting other regions is a difficult task. It is desirable to target the particular tissue where the chemical has its biological effect. To study this phenomenon computationally, in this work we numerically study a mathematical model which is written as a nonlinear system composed by three parabolic partial differential equations. The variables involved in the model are the concentration of the chemical, the concentration of the binding protein and the concentration of the chemical bound to the protein. Our aim is to propose a fully discrete approximation of this problem, using the Finite Element Method and a semi-implicit Euler scheme, in order to solve it numerically. This discrete problem is analysed, obtaining a discrete stability property and some a priori error estimates that show the algorithm converges linearly if the continuous solution is regular enough. Also, some representative examples are shown, as well as the numerical verification of the convergence.
Optimized Rhombic Experimental Dynamic Checkerboard Designs to Elucidate Pharmacodynamic Drug Interactions of Antibiotics
Authors: Kroemer Niklas , Aubry Romain , Couet William , Grégoire Nicolas , Wicha Sebastian G. 
Published: September 2022

AbstractPurposeQuantification of pharmacodynamic interactions is key in combination therapies, yet conventional checkerboard experiments with up to 10 by 10 combinations are labor-intensive. Therefore, this study provides optimized experimental rhombic checkerboard designs to enable an efficient interaction screening with significantly reduced experimental workload.MethodsBased on the general pharmacodynamic interaction (GPDI) model implemented in Bliss Independence, a novel rhombic ‘dynamic’ checkerboard design with quantification of bacteria instead of turbidity as endpoint was developed. In stochastic simulations and estimations (SSE), the precision and accuracy of interaction parameter estimations and classification rates of conventional reference designs and the newly proposed rhombic designs based on effective concentrations (EC) were compared.ResultsAlthough a conventional rich design with 20-times as many combination scenarios provided estimates of interaction parameters with higher accuracy, precision and classification rates, the optimized rhombic designs with one natural growth scenario, three monotherapy scenarios per combination partner and only four combination scenarios were still superior to conventional reduced designs with twice as many combination scenarios. Additionally, the rhombic designs were able to identify whether an interaction occurred as a shift on maximum effect or EC50 with > 98%. Overall, effective concentration-based designs were found to be superior to traditional standard concentrations, but were more challenged by strong interaction sizes exceeding their adaptive concentration ranges.ConclusionThe rhombic designs proposed in this study enable a reduction of resources and labor and can be a tool to streamline higher throughput in drug interaction screening.
Willingness to pay for automated taxis: a stated choice experiment to measure the impact of in-vehicle features and customer reviews
Authors: Yin Hao , Cherchi Elisabetta 
Published: September 2022

AbstractThis study aims to contribute to the limited empirical evidence on Automated Taxis (ATs) by analysing the in-vehicle features that ATs ought to have to satisfy taxi passengers requests that in a Normal Taxi (NT) are dealt with a direct communication between the passenger and the driver. Based on the results of focus groups and several pilots, two in-vehicle features are tested: change of destination and chat with an operator during the trip. The paper also contributes to the body of literature on the impact of social influence on the adoption of innovation by testing the impact of consumer reviews other than the typical measure of adoption and injunctive norms. A Stated Choice (SC) experiment was built putting particular effort in the definition and presentation of the new attributes tested. The study was applied in China among current users of NTs (i.e. with the driver). Hybrid choice models were estimated and a resampling technique was used to test the model sensitivity to the sample gathered. Results show that on average, Chinese taxi users are willing to pay 0.35 Euros to have the option to ‘change the destination’ and 0.78 Euros to be able to ‘chat with an operator’ inside the AT. Among the social influence attributes, the reviews from previous customers confirmed to be the most effective measure, users are willing to pay 1.58 Euros more to use a taxi that got good reviews for long trips (≥ 30 min) and 0.57 Euros for shorter trips. The Willingness to Pay (WTP) estimated are all significant at more than 95% and have a narrow confidence intervals.
Do political protests mobilize voters? Evidence from the Black Lives Matter protests
Authors: Engist Oliver , Schafmeister Felix 
Published: September 2022

AbstractIn this article, we study the local political mobilization effects of political protests in the context of the Black Lives Matter (BLM) movement. We analyze monthly voter registration data from 2136 US counties across 32 states, leveraging variation in the exposure to BLM protests across counties in a two-way fixed-effects framework with a matched control group. In contrast to previous studies, which reported substantial mobilization effects of local protests in other contexts, we show that voter registrations in the aggregate were insensitive to the presence of local BLM protests. We further disentangle the effects along party lines and the degree to which protests were associated with violent behaviors and find similarly insignificant effects. We present some preliminary evidence that the large scale of the protests and their extensive news coverage might have reduced the importance of experiencing a protest firsthand.
Global value chains, financial constraints, and innovation
Authors: Elshaarawy Rawan , Ezzat Riham A. 
Published: September 2022

AbstractThis paper analyzes the effect of firms engaging in global value chains (GVCs) and suffering from financial constraints on innovation. To explore this relationship, this study relies on firm-level data from World Bank Enterprise Surveys (WBES) for 146 countries during the period between 2006 and 2020. The aim of this paper is to empirically link two literature strands, the one of GVC participation and that of financial constraints, and to examine their individual effects, in addition to the effect of their interaction on innovation. Extended probit model is used to account for the endogeneity problem that may arise when studying the effect of GVC participation and financial constraints on innovation, by using a set of instrumental variables. This paper controls for heterogeneity among firms (by country, region, and industry), firms’ characteristics, reverse causality, and sample selection. The results of this paper show that financial constraints impede firms’ probability of innovation even if the firm is participating in GVC. This means that the negative effects of financial constraints outweigh the positive effects of GVC participation on innovation.