bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pregnancy complications and intimate partner violence: The moderating role of prenatal posttraumatic stress symptoms
Authors: Gilliam Hannah C. , Howell Kathryn H. , Paulson Julia L. , Napier Taylor R. , Miller‐Graff Laura E. 
Published: June 2022

AbstractIntimate partner violence (IPV) and posttraumatic stress disorder increase the risk of poor pregnancy outcomes, but associations among IPV exposure, mental health, and pregnancy complications remain underexplored. This study assessed the interaction between three types of IPV exposure (i.e., physical, sexual, psychological) and posttraumatic stress symptoms (PTSS) on prenatal complications (e.g., preeclampsia, gestational diabetes) among pregnant women exposed to IPV. Participants included 137 IPV‐exposed pregnant women (Mage = 27.29, SD = 6.00; 66.9% African American/Black). Three regression models were run to test the main effect of each type of IPV and PTSS on pregnancy complications, and the moderating effect of PTSS on the association between IPV and pregnancy complications, controlling for socioeconomic status, gestational age, and childhood trauma. Main effects were observed for sexual coercion, β = .32, p = .010, R2part = .050, and PTSS, β = 0.19, p = .039, R2part = .026, with more frequent sexual IPV and higher levels of PTSS associated with more pregnancy complications. Moderating effects were also evident, with the IPV x PTSS interaction significant for all three IPV domains: psychological aggression, f2 = .046; sexual coercion, f2 = .079; and physical assault, f2 = .048. PTSS strengthened the positive association between psychological and sexual IPV and pregnancy complications. Physical IPV and pregnancy complications were inversely related for participants with low‐level PTSS. Results provide novel information on how IPV types and PTSS function together during pregnancy. Findings highlight the need for evidence‐based prenatal interventions that successfully address both IPV exposure and PTSS severity.
Does Cystocele Type Vary Between Vaginally Parous and Nulliparous Women?
Authors: Vereeck Sascha , Pacquée Stefaan , Jacquemyn Yves , Neels Hedwig , De Wachter Stefan , Weeg Natalie , Dietz Hans Peter 
Published: June 2022

ObjectivesTo evaluate whether cystocele type varies with vaginal parity.MethodsRetrospective analysis of 464 vaginally nulliparous women seen at 2 urogynecology units between November 2006 and November 2019. A control group consisted of 871 vaginally parous women seen between July 2017 and November 2019. Patients underwent a standardized interview, POPQ, urodynamic testing, and translabial ultrasound. On imaging, significant cystocele was defined as bladder descent to ≥10 mm below symphysis pubis. Volume datasets were analyzed offline and blinded against clinical data.ResultsOf 5266 women seen during the inclusion period, 464 were vaginally nulliparous. Three were excluded due to missing data, leaving 461. A control group of 871 parous women was generated from patients seen during the last 2.5 years of the inclusion period. Vaginally nulliparous women were presented at a younger age compared to vaginally parous women (P < .001). Symptoms of prolapse were reported in 104 (22%) nulliparae and 489 (56%) parous women (P < .0001). Vaginally parous women demonstrated more bladder descent (P < .0001) and more cystocele (418/871 versus 43/461, P < .0001), with a higher proportion of type III cystocele (cystocele with intact retrovesical angle) (20/43 versus 273/ 418, P < .0001). Cystourethrocele (Green type II) was more common in nulliparae and cystocele type III in parous women (P = .015). On multivariate analysis, these differences in proportions remained significant (P = .049).ConclusionsNulliparity was associated with a higher proportion of Green type II cystoceles. Green type III cystocele was more common in vaginally parous women, suggesting that the latter may be more likely to be due to childbirth‐related pelvic floor trauma.
Hypothyroidism After Using Superior Thyroid Artery as A Recipient Artery
Authors: Nakamura Ryota , Takanari Keisuke , Hanai Nobuhiro , Suzuki Hidenori , Nishikawa Daisuke , Okumura Seiko , Maruyama Yoko , Hyodo Ikuo 
Published: June 2022

ObjectiveSuperior thyroid artery (SThA) is a common recipient artery in free tissue transfer even after total pharyngolaryngoesophagectomy (TPLE) with hemithyroidectomy. The aim of this study was to evaluate whether the use of SThA as a recipient vessel affect thyroid function in patients undergoing TPLE with hemithyroidectomy.MethodsFrom 2011 to 2020, 91 patients who underwent free jejunum transfer after TPLE with hemithyroidectomy were divided into two groups. In Group1 (n = 47), the contralateral SThA was used for the anastomosis. In Group2 (n = 44), other vessels were used. Retrospective chart review was performed comparing postoperative thyroid function between two groups.ResultsIn group1, 17 patients presented hypothyroidism, 21 presented latent hypothyroidism and 9 presented no thyroid dysfunction comparing 15, 19, and 10 respectively in group 2. There were no significant differences between the two groups.ConclusionEven after hemithyroidectomy, with inferior thyroid arteries are preserved, the SThA can be used as a recipient vessel.Level of Evidence3 Laryngoscope, 133:557–561, 2023
Improvement of corrosion and stress corrosion properties of magnesium alloys by coating aluminum with the electric arc spray method
Authors: Catar Recep , Altun Hikmet 
Published: June 2022

AbstractIn this study, corrosion and stress corrosion behaviors of AZ31, AZ61, and AZ91 magnesium alloys coated with aluminum by the electric arc spray method were investigated in 3.5 wt.% NaCl solution. Structural properties of coated materials were investigated by scanning electron microscopy (SEM), energy dispersive X‐ray analysis, and X‐ray diffraction. Electrochemical properties were determined using the potentiodynamic polarization method in 3.5 wt.% NaCl solution. Potentiodynamic polarization curves showed that corrosion current density values did not change with coating in aluminum‐coated samples by the electric arc spray method. In contrast, corrosion potential value increased toward positive values. Slow strain rate test (SSRT) was used to determine the stress corrosion behavior and stress corrosion indexes (ISCC), ultimate tensile strength (UTS), and elongation of AZ31, AZ61, and AZ91 magnesium (Mg) alloys were determined. As a result of the SSRT, the aluminum coating process decreased significantly the stress corrosion indexes of AZ31, AZ61, and AZ91 Mg alloys. The fracture of surface images was also examined in the SEM, and both intergranular and transgranular stress corrosion cracking were observed in all three alloys.
Porous Poly(3,4‐ethylenedioxythiophene)‐Based Electrodes for Detecting Stress Biomarkers in Artificial Urine and Sweat
Authors: Borras Nuria , Sánchez‐Jiménez Margarita , Casanovas Jordi , Alemán Carlos , Pérez‐Madrigal Maria M. 
Published: June 2022

AbstractWhen danger is perceived, the human body responds to overcome obstacles and survive a stressful situation; however, sustained levels of stress are associated with health disorders and diminished life quality. Hence, stress biomarkers are monitored to control stress quantitatively. Herein, a porous sensor (4l‐COP/p) composed of poly(3,4‐ethylenedioxythiophene) (PEDOT) and poly(3,4‐ethylenedioxythiophene‐co‐N‐methylpyrrole) (COP), which is prepared in a four‐layered fashion to detect dopamine (DA) and serotonin (5‐HT), is presented. Specifically, the detection is conducted in phosphate‐buffered saline (PBS), as well as artificial urine and sweat, by applying cyclic voltammetry. The limit of detection values obtained are as low as 5.7 × 10−6 and 1.4 × 10−6 m for DA and 5‐HT, respectively, when assessed individually in artificial urine. When mixed in PBS, 4l‐COP/p detects both biomarkers with a resolution of 0.18 V and a sensitivity of 40 and 30 µA mm−1 for DA and 5‐HT, respectively. Additionally, by theoretical calculations, the interaction pattern that each stress biomarker establishes with the PEDOT outer layer is elucidated. Whereas DA interacts with the π‐system of PEDOT, 5‐HT forms specific hydrogen bonds with the conducting polymer chains. The resolution value obtained depends upon such interactions. Overall, 4l‐COP/p electrodes display potential as stress sensing devices for healthcare technologies.
Internally Functionalized Dendrimers Based on Fully Substituted 1,2,3‐Triazoles
Authors: Niu Lijiao , Song Ningning , Wang Xiaojun , Ding Shengtao 
Published: June 2022

AbstractBeing one important class in dendrimer chemistry, internally functionalized dendrimers (IFDs) are still exiguous. Here, the first construction of IFDs involving fully substituted 1,2,3‐triazole rings as interior functionality carriers is demonstrated. Through divergent or convergent synthetic protocols established on the efficient iridium‐catalyzed annulation of internal 1‐thioalkynes with organic azides, sequence‐controlled heterolayered dendrimers with different branched structures are achieved in a convenient manner. 1H NMR, mass spectrometry, and size exclusion chromatography characterizations well identify their architecture and high purity.
Striatal Blood–Brain Barrier Opening in Parkinson's Disease Dementia: A Pilot Exploratory Study
Authors: Pineda‐Pardo José A. , Gasca‐Salas Carmen , Fernández‐Rodríguez Beatriz , Rodríguez‐Rojas Rafael , del Álamo Marta , Obeso Ignacio , Hernández‐Fernández Frida , Trompeta Clara , Martínez‐Fernández Raúl , Matarazzo Michele , Mata‐Marín David , Guida Pasqualina , Duque Alicia , Albillo David , Plaza de las Heras Isabel , Montero Juan I. , Foffani Guglielmo , Toltsis Gabriella , Rachmilevitch Itay , Blesa Javier , Obeso José A. 
Published: June 2022

AbstractBackgroundParkinson's disease (PD) exhibits a high prevalence of dementia as disease severity and duration progress. Focused ultrasound (FUS) has been applied for transient blood–brain barrier (BBB) opening of cortical regions in neurodegenerative disorders. The striatum is a primary target for delivery of putative therapeutic agents in PD.ObjectiveHere, we report a prospective, single‐arm, nonrandomized, proof‐of‐concept, phase I clinical trial (NCT03608553 amended) in PD with dementia to test the safety and feasibility of striatal BBB opening in PD patients.MethodsSeven PD patients with cognitive impairment were treated for BBB opening in the posterior putamen. This was performed in two sessions separated by 2 to 4 weeks, where the second session included bilateral putamina opening in 3 patients. Primary outcome measures included safety and feasibility of focal striatal BBB opening. Changes in motor and cognitive functions, magnetic resonance imaging (MRI), 18F‐fluorodopa (FDOPA), and β‐amyloid PET (positron emission tomography) images were determined.ResultsThe procedure was feasible and well tolerated, with no serious adverse events. No neurologically relevant change in motor and cognitive (battery of neuropsychological tests) functions was recognized at follow‐up. MRI revealed putamen BBB closing shortly after treatment (24 hours to 14 days) and ruled out hemorrhagic and ischemic lesions. There was a discrete but significant reduction in β‐amyloid uptake in the targeted region and no change in FDOPA PET.ConclusionsThese initial results indicate that FUS‐mediated striatal BBB opening is feasible and safe and therefore could become an effective tool to facilitate the delivery of putative neurorestorative molecules in PD. © 2022 International Parkinson and Movement Disorder Society.
The application of predefined weather patterns over India within probabilistic medium‐range forecasting tools for high‐impact weather
Authors: Neal Robert , Guentchev Galina , Arulalan T , Robbins Joanne , Crocker Ric , Mitra Ashis , Jayakumar A. 
Published: June 2022

AbstractA method is presented for deriving probabilistic medium‐range (1‐to‐2‐week) weather pattern forecasts for India. This method uses an existing set of 30 objectively derived daily weather patterns, which provide climatological representations for unique states in the large‐scale circulation over India. Weather pattern forecast probabilities are based on the number of ensemble members objectively assigned to each weather pattern. Two summer monsoon case studies illustrate the best use of the forecasting tool within medium‐range guidance, such as highlighting the most likely weather pattern transitions and relating these to the likelihood of weather impacts. Forecast skill is evident out to at least 10–15 days. Winter dry period weather patterns have the highest forecast skill, closely followed by retreating monsoon weather patterns. In contrast, monsoon onset and break monsoon weather patterns have the lowest forecast skill. Finally, a prototype weather pattern forecast climatology application is presented for use in highlighting when extreme rainfall is more likely than normal. This application is based on weather pattern empirical probabilities of threshold exceedances using a high‐resolution regional reanalysis. The transitional pre‐ and post‐monsoon seasons have the greatest variability in rainfall across all possible weather patterns, with a slight dip in variability during the main summer monsoon season. In contrast, very little variability across weather patterns is evident during the relatively dry winter months. This highlights the times of year when a climatology‐based weather pattern forecasting approach may have its greatest benefits over that of a basic daily climatology.
Efficient reliability‐based design of slope angles in spatially variable soils with field data
Authors: Jiang Shui‐Hua , Liu Xian , Huang Jinsong , Zhou Chuang‐Bing 
Published: June 2022

AbstractDeterministic single factor of safety method cannot explicitly account for the influences of various sources of uncertainties (e.g., spatial variability of geomaterials, measurement and transformation uncertainties) in stability design of slopes. Many probabilistic methods have been applied to the reliability‐based design (RBD) of slopes, but they typically require performing numerous deterministic slope stability analyses. In this paper, an efficient reliability‐based design method for spatially varying slopes based on field data is proposed. Here, the RBD of a slope angle is concerned. Reliability‐based design is implemented using an inverse First Order Reliability Method (inverse FORM ‐ IFORM). A sandy slope and a cohesive slope are investigated as examples, respectively, to illustrate the proposed method. The results indicate that the proposed method can quickly obtain rational design schemes of slope angles accounting for the spatial variability of soil properties, measurement and transformation uncertainties based on the field data. It can act as a practical and effective tool for the RBD of slopes in two‐dimensional spatially variable soils. Additionally, it is found that the random field mesh size affects the RBD results significantly, while the probability distribution and horizontal autocorrelation of soil parameters have slight influences on the RBD results.
A fully second‐order homogenization formulation for the multi‐scale modeling of heterogeneous materials
Authors: Rodrigues Lopes Igor A. , Andrade Pires Francisco M. 
Published: June 2022

AbstractA homogenization‐based multi‐scale model at finite strains is proposed linking the micro‐scale to the macro‐scale level through a second‐gradient constitutive theory. It is suitable for modeling localization and size effects in multi‐phase materials. The macroscopic deformation gradient and second gradient are enforced on a microstructural representative volume element (RVE). The coupling between the scales is defined by means of kinematical insertion and homogenization operators, carefully postulated to ensure kinematical conservation in the scale transition, according to the method of multi‐scale virtual power. From the solution of the micro‐scale equilibrium, the macroscopic stress tensors are derived based on the principle of multi‐scale virtual power. The kinematical constraints at the RVE level are enforced with Lagrange multipliers. A mixed finite element approach is adopted for the numerical solution of the micro and macro second gradient equilibrium problems. It conveniently leads to a formulation where the Lagrange multipliers are the homogenized stresses, and the macroscopic consistent tangent operators for FE2 simulations can be directly derived. The Newton–Raphson scheme is employed to solve the non‐linear systems of equations. The numerical results demonstrate the predictive capability of the proposed model. A systematic analysis of the influence of RVE length and the micro‐constituent size is performed.
A robust, stretchable, transparent, solvent‐resistant, and fluorescent composite: Anchoring carbon dots in polyurethane to obtain new photoluminescent emissions
Authors: Li Na , Wu Sha , Luo Dan , Liang Guangming , Xiao Yulong , Xu Lei , Wang Rui , Xiao Yao , He Ping 
Published: June 2022

AbstractCarbon dots (CDs) exhibit vivid photoluminescence in solutions, but show no or weak photoluminescent emissions in solid state. In this paper, we prepared a polyurethane (PU)/CD composite with solid‐state fluorescence under ultraviolet (UV) irradiation by anchoring oil‐soluble CDs in a crosslinked PU matrix through chemical reaction. This polymer composite has high robustness, transmittance, and organic solvent resistance, as well as good stretching ability. Interestingly, since the chemical reaction between the CDs and the PU matrix changes the UV absorption feature of the CDs, the PU/CD composite has blue (near 405 nm), cyan (near 470 nm), and green (near 495 nm) fluorescent emissions, even though the CD solution just possesses green (near 530 nm) fluorescent emissions. This PU/CD composite shows the possibility of application in optoelectronic devices.
Secondary trauma, burnout, and teacher self‐care during COVID19: A mixed‐methods case study
Authors: McMakin Deborah , Ballin Amy , Fullerton Diana 
Published: June 2022

AbstractManifestations of teacher burnout have been negatively associated with students' academic achievement, school satisfaction, and perceived teacher support. The 2020–2021 school year presented unique challenges for teachers, who had to find new ways to support their students, their families, and themselves. This study examined teachers' experiences with secondary trauma, burnout, and self‐care during COVID‐19 at one K‐5 trauma‐informed school, the Wellington (pseudonym). We chose a mixed‐methods convergent design utilizing both qualitative and quantitative data to support the findings. Using three measures, the Professional Quality of Life Scale, Mindful Self‐Care Scale, and Teaching Self‐Efficacy Scale, in fall 2020 and spring 2021, we examined 19 faculty and educational staff members' perceptions of and experiences with secondary trauma, burnout, and self‐care. In spring 2021 we interviewed 13 of these teachers. Teachers noted how COVID‐19 brought increased responsibilities at home and school, as well as disrupted self‐care routines. However, data indicate stable compassion satisfaction, low secondary trauma, and average range burnout. Notably, faculty reported self‐care in the form of supportive relationships and sense of purpose. These findings suggest that a trauma‐informed approach may foster a supportive work environment, mitigating burnout.
Optimizing use of written peer support as a supportive resource in cancer: Focus group insights
Authors: Rini Christine , Waltz Margaret , Bovbjerg Katrin , Farrell David , Yanez Betina , Chicaiza Anthony , Hartstein Madison L. , Omar Rahma , Thompson Rebecca , Rowley Scott D. , Stanton Annette L. , Valdimarsdottir Heiddis , Austin Jane , Van Denburg Alyssa N. , Graves Kristi D. 
Published: June 2022

AbstractPurposeCancer survivors frequently describe wanting to learn from others who have had similar diagnoses or treatments (peer support). We conducted focus groups to investigate hematopoietic stem cell transplant survivors' attitudes and preferences regarding accessing written peer support through a website. Although written peer support does not allow for interpersonal interactions with peers, it could increase transplant recipients' access to evidence‐based benefits of informational and emotional peer support.MethodsWe conducted four videoconference focus groups with 34 adult transplant survivors who were diverse in their medical and sociodemographic characteristics and geographic location. Discussions were recorded, transcribed, and content analyzed.ResultsMany participants reported need for information about transplant beyond what they received from their healthcare providers. Needs varied across participants, as did preferences for characteristics and timing of information optimally provided through peer support. Participants were enthusiastic about the value of written peer support but emphasized that it should be delivered in a way that accommodates variation in transplant experiences, underscores its trustworthiness, and pairs it with useful psychoeducational content.ConclusionsFindings provide guidance for making written peer support an accessible, supportive resource for transplant survivors. Future research should evaluate personalized online delivery of written peer support paired with psychoeducational content that enhances its benefits.Implications for Cancer Survivors: Written peer support delivered online could be a useful, valued resource for transplant survivors.
Elevated serum CEA is associated with liver metastasis and distinctive circulating tumor DNA alterations in patients with castration‐resistant prostate cancer
Authors: Bray Alexander W. , Duan Rong , Malalur Pannaga , Drusbosky Leylah M. , Gourdin Theodore S. , Hill Elizabeth G. , Lilly Michael B. 
Published: June 2022

AbstractBackgroundElevated serum carcinoembryonic antigen (CEA) is used to identify “treatment emergent” forms of castration‐resistant prostate cancer (CRPC) such as aggressive variant prostate cancer (AVPC). However, its individual utility as a prognostic marker and the genetic alterations associated with its expression have not been extensively studied in CRPC.MethodsThis study retrospectively analyzed clinical outcomes and circulating tumor DNA profiles in 163 patients with CRPC and elevated or normal serum CEA. These same patients were then classified as AVPC or non‐AVPC and compared to determine the uniqueness of CEA‐associated gene alterations.ResultsPatients with elevated CEA demonstrated higher rates of liver metastasis (37.5% vs. 19.1%, p = 0.02) and decreased median overall survival from CRPC diagnosis (28.7 vs. 73.2 mo, p < 0.0001). In addition, patients with elevated CEA were more likely to harbor copy number amplifications (CNAs) in AR, PIK3CA, MYC, BRAF, CDK6, MET, CCNE1, KIT, RAF1, and KRAS. Based on variant allele frequency we also defined “clonal” single‐nucleotide variants (SNVs) thought to be driving disease progression in each patient and found that CEA expression was negatively correlated with clonal AR SNVs and positively correlated with clonal TP53 SNVs. Of these genetic associations, only the increases in clonal TP53 SNVs and KRAS amplifications were recapitulated among patients with AVPC when compared to patients without AVPC.ConclusionsTogether these findings suggest that CEA expression in CRPC is associated with aggressive clinical behavior and gene alterations distinct from those in AVPC.