bluuebunny/crossref_metadata_2025_split huggingface dataset:
O que é a teoria queer? Notas introdutórias de um saber subalterno, subversivo e contra-hegemônico
Authors: Celestino de Jesus Cassiano 
Published: May 2022

A moral não é queer. Nem a lei. Nem o direito. Isto é certo. Porém, a certeza tampouco é queer. O governo nunca é queer. Entretanto, dizer “nunca” não é nada queer. O gay talvez seja queer. Mas, afinal, o que é o queer? Provocativo e polêmico, o queer, como movimento e teoria, vem sendo ensaiado e contestado, internacionalmente e no Brasil. Mais do que traduções, classificações ou definições, o objetivo aqui é, de modo muito breve e didático, apresentar a vertente do pensamento conhecida como Teoria Queer, suas ideias-chave, conceitos e sugestões. Com este trabalho, esperamos compreender um pouco mais o desenvolvimento das investigações científicas sobre tal temática em nosso país.
Enhancing Transition Dipole Moments of Heterocyclic Semiconductors via Rational Nitrogen‐Substitution for Sensitive Near Infrared Detection
Authors: Wang Wei , Miao Xiaodan , Cai Guilong , Ding Li , Li Yawen , Li Tengfei , Zhu Yufan , Tao Liting , Jia Yixiao , Liang Yuanxin , Lu Xinhui , Fang Yanjun , Yi Yuanping , Lin Yuze 
Published: May 2022

AbstractDesigning ultrastrong near‐infrared (NIR) absorbing organic semiconductors is a critical prerequisite for sensitive NIR thin film organic photodetectors (OPDs), especially in the region of beyond 900 nm, where the absorption coefficient of commercial single crystalline silicon (c‐Si) is below 103 cm−1. Herein, a pyrrolo[3,2‐b]thieno[2,3‐d]pyrrole heterocyclic core (named as BPPT) with strong electron‐donating property and stretched geometry is developed. Relative to their analogue Y6, BPPT‐contained molecules, BPPT‐4F and BPPT‐4Cl, show substantially upshifted and more delocalized highest occupied molecular orbitals, and larger transition dipole moments, leading to bathochromic and hyperchromic absorption spectra extending beyond 1000 nm with very large absorption coefficients (up to 3.7–4.3 × 105 cm−1) as thin films. These values are much higher than those (104 to 1 × 105 cm−1) of typical organic semiconductors, and 1–2 orders higher than those of commercial inorganic materials, such as c‐Si, Ge, and InGaAs. The OPDs based on BPPT‐4F or BPPT‐4Cl blending polymer PBDB‐T show high detectivity of above 1012 Jones in a wide wavelength range of 310–1010 nm with excellent peak values of 1.3–2.2 × 1013 Jones, respectively, which are comparable with and even better than those commercial inorganic photodetectors.
Interictal SEEG Resting‐State Connectivity Localizes the Seizure Onset Zone and Predicts Seizure Outcome
Authors: Jiang Haiteng , Kokkinos Vasileios , Ye Shuai , Urban Alexandra , Bagić Anto , Richardson Mark , He Bin 
Published: May 2022

AbstractLocalization of epileptogenic zone currently requires prolonged intracranial recordings to capture seizure, which may take days to weeks. The authors developed a novel method to identify the seizure onset zone (SOZ) and predict seizure outcome using short‐time resting‐state stereotacticelectroencephalography (SEEG) data. In a cohort of 27 drug‐resistant epilepsy patients, the authors estimated the information flow via directional connectivity and inferred the excitation‐inhibition ratio from the 1/fpower slope. They hypothesized that the antagonism of information flow at multiple frequencies between SOZ and non‐SOZ underlying the relatively stable epilepsy resting state could be related to the disrupted excitation‐inhibition balance. They found flatter 1/fpower slope in non‐SOZ regions compared to the SOZ, with dominant information flow from non‐SOZ to SOZ regions. Greater differences in resting‐state information flow between SOZ and non‐SOZ regions are associated with favorable seizure outcome. By integrating a balanced random forest model with resting‐state connectivity, their method localized the SOZ with an accuracy of 88% and predicted the seizure outcome with an accuracy of 92% using clinically determined SOZ. Overall, this study suggests that brief resting‐state SEEG data can significantly facilitate the identification of SOZ and may eventually predict seizure outcomes without requiring long‐term ictal recordings.
Development of a kinetics‐integrated CFD model for the industrial scale‐up of DHA fermentation using Schizochytrium sp.
Authors: Du Yuan‐Hang , Tong Ling‐Ling , Wang Yue , Liu Meng‐Zhen , Yuan Li , Mu Xin‐Ya , He Shao‐Jie , Wei Shi‐Xiang , Zhang Yi‐Dan , Chen Zi‐Lei , Zhang Zhi‐Dong , Guo Dong‐Sheng 
Published: May 2022

AbstractIn this work, a kinetics‐integrated CFD model based on coupling computational fluid dynamics (CFD) and biokinetic was developed to guide the industrial scale‐up for fermentation of docosahexaenoic acid (DHA). Two‐substrate biokinetic equations for a 5 L bioreactor with oxygen and nitrogen source as limiting substrates were established, which were further coupled with CFD to simulate the biomass growth and lipid accumulation as well as flow field environment in the fermentation process. The coupled CFD‐biokinetic model can accurately reflect the changes of each relevant variable in the 50 L bioreactor under different operating conditions. The optimal working conditions of a 35 m3 bioreactor were predicted by this model and have secured the one‐step scale‐up of DHA fermentation, resulting in a biomass, lipid concentration, and DHA content in lipids of 99.2 g/L, 55.7 g/L, and 52.5%, respectively. This study thus provides an effective strategy for rapid industrial scale‐up of DHA production.
Efficient Greener Visible‐Light‐Catalyzed Debenzylation of Benzyl Ethers and Esters: A Gateway to Wider Exploitation of Stable Benzyl Protecting Groups
Authors: Bhuyan Samuzal , Mandal Susanta , Jana Saibal , Chhetri Karan , Roy Biswajit Gopal 
Published: May 2022

AbstractA non‐hydrogenolytic mild deprotection strategy for stable benzyl protection of hydroxyl group is one of the long‐cherished goals in multistep synthesis involving carbohydrates or compounds with multiple hydroxyl groups. A greener organo‐photocatalytic method has been developed for mild and efficient visible light catalytic deprotection of benzyl group from benzyl ether and benzyl ester. The newly developed method in ambient condition with only 1 mol% of catalyst loading can efficiently remove highly stable benzyl protection from ethers and esters of wide substrate scope with excellent functional group tolerance, thus proved to be suitable for final stage deprotection. Employment of molecular oxygen as terminal oxidant and excellent yield in the multigram scale reaction signifies the eco‐friendliness, robustness and industrial applicability of the method.
Simple length‐based approaches offer guidance for conservation and sustainability actions in two Central American small‐scale fisheries
Authors: Tewfik Alexander , Babcock Elizabeth A. , Phillips Myles , Moreira‐Ramírez José F. , Polanco Francisco , Marroquin Jorge , Castillo Miriam , Auil Gomez Nicole , McNab Roan 
Published: May 2022

Abstract

Many species targeted by multi‐gear small‐scale fisheries in developing countries are poorly studied in terms of fisheries sustainability even as their contributions to biodiversity, livelihoods, export earnings and food security are well documented.
This study presents new information on more than 150 fish species that constitute the bulk of small‐scale fishery landings in Belize and on the Pacific coast of Guatemala to provide guidance for improved biodiversity conservation and fisheries management. This includes a number of species listed as threatened on the IUCN Red List and Appendix II of CITES.
Simple, length‐based approaches and thresholds of size at maturity show that many of the elasmobranch and bony fish species examined have many immature individuals landed (Belize 51%, Guatemala 77%) across several gears.
In both countries, maximum size is negatively correlated with the intensity of overfishing for several common metrics: proportions of mature, optimal sized and mega‐spawners. The disproportionate removal of the largest species first will have cascading effects on biodiversity, community structure and species interactions, as well as livelihood opportunities and food security for fishing communities.
Status indicators, such as fishing mortality rate relative to natural mortality rate and estimates of depletion based on lengths are sensitive to the assumed values of life history parameters, indicating the importance of improved data on growth, maturity and mortality for these populations.
Our study emphasizes the use of a combination of fisheries conservation strategies, including size and effort controls, in conjunction with the closed area concept (i.e. marine protected areas) and meaningful consultation with resource users in order to maximize benefits for nature and people.
Interactions between the common dolphin, Delphinus delphis, and the Portuguese purse seine fishery over a period of 15 years (2003–2018)
Authors: Dias Inês C. , Marçalo Ana , Feijó Diana , Domingos Isabel , Silva Alexandra A. 
Published: May 2022

Abstract

Interactions between cetaceans and the purse seine fishery in coastal waters of mainland Portugal were investigated using onboard observations over a period of 15 years (2003–2018). In 10% of the fishing sets, there were interactions with one of three species of cetaceans: common dolphin (Delphinus delphis), bottlenose dolphin (Tursiops truncatus), and harbour porpoise (Phocoena phocoena). The common dolphin was the most frequently observed species, occurring in 89% of all interaction events, and the only species with observed mortality. Therefore, this study focused only on the interactions with common dolphins.
A generalized additive model (GAM) was applied to observer data to investigate how the fishing activity and the abundance of small pelagic fish influenced the probability of occurrence of interactions between the common dolphin and the purse seine fishery between 2003 and 2018. The results revealed significant annual and geographic variation in the occurrence of interactions, and a significant influence of fishing effort and catch per unit effort of sardine (Sardina pilchardus).
A second GAM in a hurdle model was used to model the number of common dolphins that interacted with the fishing activity as a function of fishing seasonality and the local abundance of pelagic fish. There was a significant effect of the seasonality of the fishing activity and catch per unit effort of sardine and chub mackerel (Scomber colias) on the number of common dolphins interacting with the fishery.
The results of this study suggest that the probability of interactions and the number of common dolphins interacting with the fishery were affected by the local abundance of sardine and chub mackerel.
As the common dolphin population appears to be increasing in the study area, the risk of by‐catch also increases, thus the monitoring of the Portuguese purse seine fishery is important to inform the implementation of management plans, and also as a response to global efforts for sustainable fisheries and marine mammal conservation.
Dynamic event‐triggered H∞$$ {H}_{\infty } $$ control for continuous‐time singular system with cyber attacks
Authors: Wang Heqian , Yang Qingsheng , Wu Jie , Zhan Xisheng , Yan Huaicheng 
Published: May 2022

AbstractThis essay discusses the
control for continuous‐time singular systems with two types of stochastic cyber attacks and dynamic event‐triggered scheme. So as to economize network resources and reduce communication burden, the novel dynamic event‐triggered mechanism is given. Cyber attacks occur randomly during network information transmission, especially the denial of service (DoS) attacks and the deception attacks. By using Lyapunov–Krasovskii functional, some novel sufficient conditions for the impulse free, regular, and asymptotically stable of the studied system are obtained, and a corresponding controller is devised. In addition, a desired controller gain is received through resolving linear matrix inequalities. Eventually, a few numerical examples are supplied to certify the usefulness of provided design ways and results.
Hansen’s disease masquerading as rheumatoid arthritis: A case report
Authors: Pant Prashant , Shrestha Oshan , Singh Pragyat , Paudyal Vivek , Alam Istiyaque , Rajput Prabhat Singh , Shrestha Dhan Bahadur 
Published: May 2022

AbstractHansen's disease, a chronic granulomatous disease, classically has cutaneous and neurological manifestations. Musculoskeletal manifestation of the disease is underappreciated. This case report conveys that musculoskeletal manifestation of the disease should not be missed, as sometimes it is the only presenting symptom, to avoid delay in correct diagnosis and treatment.
Immunotherapy using Histobulin™ in psoriasis: A case report
Authors: Kim Hyuk Soon , Noh Geunwoong 
Published: May 2022

AbstractThere is no cure for psoriasis. A psoriasis patient was treated with Histobulin™. The patient's clinical symptoms and signs disappeared after the eighth injection and did not recur for more than 18 months. Histobulin™ was effective in the treatment of psoriasis and is suggested as a curative therapeutic for psoriasis.
Hypertriglyceridemia‐induced pancreatitis after egg retrieval for in vitro fertilization and fenofibrate cessation
Authors: Shrimanker Tushaar V. , Retalis Zachary , Hussein Khalil Ian 
Published: May 2022

AbstractA 36‐year‐old woman with prior hypertriglyceridemia‐induced pancreatitis presented with a recurrence of pancreatitis after beginning in vitro fertilization (IVF). Her primary care physician had discontinued fenofibrate due to concerns for teratogenicity. This case illustrates the importance of fibrate therapy for high‐risk women undergoing IVF, despite limited evidence regarding its teratogenicity.
Adjuvant immunotherapy in patients with high‐risk muscle‐invasive urothelial carcinoma: The potential impact of informative censoring
Authors: Martini Alberto , Yu Menggang , Raggi Daniele , Joshi Himanshu , Fallara Giuseppe , Montorsi Francesco , Necchi Andrea , Galsky Matthew D. 
Published: May 2022

BACKGROUNDThe results of 2 studies exploring adjuvant immune checkpoint inhibition (aCPI) in high‐risk muscle‐invasive urothelial cancer have yielded conflicting results. A trial employing placebo as the control arm demonstrated a significant prolongation in disease‐free survival (DFS) whereas a trial employing observation as the control arm (IMvigor010) demonstrated no prolongation in DFS with CPI. Here, the authors aimed to estimate the aCPI benefit and to model the potential impact of informative censoring on trial results.METHODSSurvival data from 1518 patients was reconstructed from Kaplan‐Meier curves. A network meta‐analysis approach was used to estimate aCPI benefit through the restricted mean disease‐free survival time (RMDFST). To estimate the potential impact of informative censoring on IMvigor010, a simulation was performed. The minimum proportion of informative censoring on the observation arm that could account for the lack of observed improvement in DFS was estimated. Random variability from the time of censoring to progression was modeled using the exponential distribution.RESULTSPatients receiving aCPI had better DFS: ΔRMDFST at 36 months of 2.2 (95% CI, 0.6‐3.7,P= .006) months relative to observation/placebo. In IMvigor010, in the observation arm, 20.5% of patients were censored due to consent withdrawal, protocol violation and/or noncompliance, or lost to follow‐up versus 8.2% in the treatment arm. On simulation, it was found that the lack of observed improvement in DFS could have resulted from as few as 14% of the censored patients on observation arm not being censored at random (simulated DFS with 14% informative censoring hazard ratio, 0.83; 95% CI, 0.69‐0.99;P= .049).CONCLUSIONSPhase 3 trials comparing adjuvant therapies to observation are at risk for informative censoring that could potentially impact interpretation of study results.;
Chemostatic concentration–discharge behaviour observed in a headwater catchment underlain with discontinuous permafrost
Authors: Conroy Nathan A. , Dann Julian B. , Newman Brent D. , Heikoop Jeffrey M. , Arendt Carli , Busey Bob , Wilson Cathy J. , Wullschleger Stan D. 
Published: May 2022

AbstractConcentration–discharge dynamics were evaluated in a small (~ 2.25 km2) headwater catchment underlain with discontinuous permafrost on the Seward Peninsula of western Alaska. A large storm, during which 48 mm of rain fell over a 24‐h period, enabled the evaluation of solute concentration–discharge response to a sizeable hydrological event, while water stable isotopes enabled an appraisal of the contributions of event water. Under normal catchment conditions, chemostatic behaviour was observed for solutes typically derived from mineral weathering (e.g. calcium, magnesium, sodium and silica). The chemostatic behaviour observed for most solutes under normal catchment conditions indicated that catchment storage and residence times are sufficiently long for many solute generating reactions to approach equilibrium. Following the storm however, most solutes exhibited dilutive and highly variable behaviour. This likely indicated the exceedance of a discharge threshold where chemostatic behaviour could no longer be maintained for most solutes. Dissolved organic carbon and silica were the only solutes monitored to exhibit chemostatic behaviour during all time periods.
Broadening perspectives: The case for ecologically valid infant research
Authors: Volk Katherine T. , Abo‐Zena Mona M. 
Published: May 2022

AbstractIn response to Byers‐Heinlein, Bergmann, and Savalei's call for improved focus on reliability in infant research, this commentary focuses on re‐conceptualizing infant development (and subsequent researching of it) in such a way as to highlight the cultural nature of human development and how that must be taken into account in our research approaches. While we agree with the need to work towards more explicit standards in infant research (e.g., reliable measures, standard reporting of effect size and description of the sample), we are concerned that the fixation on measurement of quantitative data eclipses an expanded, culturally and contextually sensitive and inclusive conceptualization of reliable and ecologically valid research, particularly in infancy.
Risk, crop yields, and weather index insurance in village India
Authors: Michler Jeffrey D. , Viens Frederi G. , Shively Gerald E. 
Published: May 2022

AbstractWe investigate the sources of variability in crop yields and their relative importance in the context of weather index insurance for smallholder farmers in India. Using parcel‐level panel data, multilevel modeling, and Bayesian methods we measure how large a role seasonal variation in weather plays in explaining yield variance. Seasonal variation in weather accounts for 14%–22% of total variance in crop yields, a value that has rarely been convincingly estimated in the economics literature. These calculations shed light on the relatively low rates of uptake of index insurance by resource‐constrained farmers. The results also provide direction for designing more suitable index insurance products.
Matching theory and evidence on Covid‐19 using a stochastic network SIR model
Authors: Pesaran M. Hashem , Yang Cynthia Fan 
Published: May 2022

SummaryThis paper develops an individual‐based stochastic network SIR model for the empirical analysis of the Covid‐19 pandemic. It derives moment conditions for the number of infected and active cases for single as well as multigroup epidemic models. These moment conditions are used to investigate the identification and estimation of the transmission rates. The paper then proposes a method that jointly estimates the transmission rate and the magnitude of under‐reporting of infected cases. Empirical evidence on six European countries matches the simulated outcomes once the under‐reporting of infected cases is addressed. It is estimated that the number of actual cases could be between 4 to 10 times higher than the reported numbers in October 2020 and declined to 2 to 3 times in April 2021. The calibrated models are used in the counterfactual analyses of the impact of social distancing and vaccination on the epidemic evolution and the timing of early interventions in the United Kingdom and Germany.
Delivering a psychosocial program for older people living in retirement homes during the Covid‐19 pandemic: A process evaluation and recommendations for community interventions
Authors: Jarvis Mary Ann , Pillay Suntosh R. , Norton Lynn M. , Hiraman Nemisha , Baloyi Olivia B. 
Published: May 2022

AbstractThe Covid‐19 pandemic lockdown regulations caused retirement homes to temporarily ban in‐person visitation potentially increasing the mental health risks of older people. An opportunity arose for a multistakeholder community collaboration to design a mental health program for older people. To evaluate the process of delivering a 12‐week psychosocial program aimed at preventing loneliness, countering boredom, and providing older people in restricted settings with education about Covid‐19 during the lockdown, in Durban, South Africa. A qualitative retrospective design was used. Data from two focus groups and six semistructured individual interviews conducted with stakeholders (volunteers, social workers, and residents) postproject were analyzed using reflexive thematic analysis. Stakeholders had varied experiences of the project, in terms of content, processes of engagement, and implementation, resulting in five themes. The study concluded with recommendations. A strong need exists for multistakeholder community collaborations when implementing a program where the context restricts physical access.
Application of metabolite set enrichment analysis on untargeted metabolomics data prioritises relevant pathways and detects novel biomarkers for inherited metabolic disorders
Authors: Hoegen Brechtje , Hampstead Juliet E. , Engelke Udo F.H. , Kulkarni Purva , Wevers Ron A. , Brunner Han G. , Coene Karlien L. M. , Gilissen Christian 
Published: May 2022

AbstractUntargeted metabolomics (UM) allows for the simultaneous measurement of hundreds of metabolites in a single analytical run. The sheer amount of data generated in UM hampers its use in patient diagnostics because manual interpretation of all features is not feasible. Here, we describe the application of a pathway‐based metabolite set enrichment analysis method to prioritise relevant biological pathways in UM data. We validate our method on a set of 55 patients with a diagnosed inherited metabolic disorder (IMD) and show that it complements feature‐based prioritisation of biomarkers by placing the features in a biological context. In addition, we find that by taking enriched pathways shared across different IMDs, we can identify common drugs and compounds that could otherwise obscure genuine disease biomarkers in an enrichment method. Finally, we demonstrate the potential of this method to identify novel candidate biomarkers for known IMDs. Our results show the added value of pathway‐based interpretation of UM data in IMD diagnostics context.
Psychology of working counseling framework applied to a gender diverse restaurant worker during COVID‐19
Authors: Hurless Nicole 
Published: May 2022

AbstractBlustein's psychology of working counseling (PWC) framework provides a foundation for contextualizing needs of gender diverse individuals within a turbulent employment landscape. Given the impact of COVID‐19 on the restaurant industry, many are navigating financial instability and challenges maintaining mental and physical health. The presented clinical case is situated in the context of restaurant work during a pandemic and incorporates considerations of intersecting identities including gender identity, class, and mental health. This article also provides interventions and professional development strategies based on PWC that career counselors can adapt to their own gender diverse clients in the restaurant industry.