bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using a daily monitoring system to reduce treatment position override rates in external beam radiation therapy
Authors: Yu Naichang , Magnelli Anthony , LaHurd Danielle , Mastroianni Anthony , Murray Eric , Close Mike , Hugebeck Brian , Suh John H. , Xia Ping 
Published: May 2022

AbstractPurpose/objectives: To report our 7‐year experience with a daily monitoring system to significantly reduce couch position overrides and errors in patient treatment positioning.Materials and methods: Treatment couch position override data were extracted from a radiation oncology–specific electronic medical record system from 2012 to 2018. During this period, we took several actions to reduce couch position overrides, including reducing the number of tolerance tables from 18 to 6, tightening tolerance limits, enforcing time outs, documenting reasons for overrides, and timely reviewing of overrides made from previous treatment day. The tolerance tables included treatment categories for head and neck (HN) (with/without cone beam CT [CBCT]), body (with/without CBCT), stereotactic body radiotherapy (SBRT), and clinical setup for electron beams. For the same time period, we also reported treatment positioning–related incidents that were recorded in our departmental incident report system. To verify our tolerance limits, we further examined couch shifts after daily kilovoltage CBCT (kV‐CBCT) for the patients treated from 2018 to 2021.Results: From 2012 to 2018, the override rate decreased from 11.2% to 1.6%/year, whereas the number of fractions treated in the department increased by 23%. The annual patient positioning error rate was also reduced from 0.019% in 2012, to 0.004% in 2017 and 0% in 2018. For patients treated under daily kV‐CBCT guidance from 2018 to 2021, the applied couch shifts after imaging registration that exceeded the tolerance limits were low, <1% for HN, <1.2% for body, and <2.6% for SBRT.Conclusions: The daily monitoring system, which enables a timely review of overrides, significantly reduced the number of treatment couch position overrides and ultimately resulted in a decrease in treatment positioning errors. For patients treated with daily kV‐CBCT guidance, couch position shifts after CBCT image guidance demonstrated a low rate of exceeding the set tolerance.
Drug Protein‐Stabilized Biomimetic Amorphous Mineral Nanoparticles as Superior Drug Carriers
Authors: Lei Jing‐Shi , Zheng Yi , Meng Yu‐Feng , Wang Fei , Feng Yan‐Hui‐Zhi , Wang Hai‐Cheng , Mao Li‐Bo , Yu Shu‐Hong , Wang Zuo‐Lin 
Published: May 2022

AbstractMinerals such as calcium carbonates and calcium phosphates are often used as drug protein carriers, which are urgently required for drug protein‐based therapy, due to their high biocompatibility. However, their performance is constrained by some obstacles, such as the low loading capacity and short circulation half‐life. Inspired by the in vivo growth of biominerals via the soluble protein‐stabilized amorphous precursors, herein drug proteins are directly used to stabilize amorphous carbonated calcium phosphate (ACCP) in a controlled mineralization environment. The bioactivity of the drugs in the ACCP carrier is preserved due to the mild synthesis condition. The intrinsically high absorption capability of the ACCP nanoparticles (NPs) leads to an ultra‐high protein loading capacity. In addition, the amorphous nature of the carrier ensures the homogeneous distribution of the protein molecules in the carrier, by which the drugs exhibit long‐term release in vitro. The effectiveness of this strategy by the high osteogenic ability of insulin‐like growth factor‐1 loaded ACCP NPs is demonstrated. Therefore, this biomimetic strategy provides a promising nanoplatform for drug protein‐based applications.
2D MBenes: A Novel Member in the Flatland
Authors: Nair Varun G. , Birowska Magdalena , Bury Dominika , Jakubczak Michał , Rosenkranz Andreas , Jastrzębska Agnieszka M. 
Published: May 2022

Abstract2D MBenes, early transition metal borides, are a very recent derivative of ternary or quaternary transition metal boride (MAB) phases and represent a new member in the flatland. Although holding great potential toward various applications, mainly theoretical knowledge about their potential properties is available. Theoretical calculations and preliminary experimental attempts demonstrate their rich chemistry, excellent reactivity, mechanical strength/stability, electrical conductivity, transition properties, and energy harvesting possibility. Compared to MXenes, MBenes’ structure appears to be more complex due to multiple crystallographic arrangements, polymorphism, and structural transformations. This makes their synthesis and subsequent delamination into single flakes challenging. Overcoming this bottleneck will enable a rational control over MBenes’ material–structure–property relationship. Innovations in MBenes’ postprocessing approaches will allow for the design of new functional systems and devices with multipurpose functionalities thus opening a promising paradigm for the conscious design of high‐performance 2D materials.
Femtosecond Laser Ablation Assisted NFC Antenna Fabrication for Smart Contact Lenses
Authors: Mirzajani Hadi , Istif Emin , Abbasiasl Taher , Mirlou Fariborz , Özkahraman Ecem Ezgi , Hasanreisoglu Murat , Beker Levent 
Published: May 2022

AbstractSmart contact lenses (SCLs) have drawn substantial interest for continuous health monitoring applications. Even though most of the reported works utilize near‐field communication (NFC) or inductive coupling for wireless powering and data transmission, developing a scalable and rapid fabrication technique for annular ring antennas confined in a small contact lens area is still an unsolved challenge. Here, femtosecond laser ablation is employed for the first time as a simple, single‐step, and highly precise fabrication technique for NFC antennas using conventional flexible printed circuit board materials. Antenna lines with depth and width of 9 and 35 μm are achieved, respectively. The antenna with a footprint of 19.5 mm2 is characterized in biological solution followed by aging, and bending tests, and a frequency deviation of less than %1 is recorded. A real‐life application is demonstrated by fabricating an SCL embedded with the antenna, an NFC chip, and an electrochemical sensor for wireless monitoring of glucose in artificial tear solution by a smartphone. The device could successfully quantify biologically relevant glucose concentrations ranging from 0.2 to 1 mM with a limit‐of‐detection of 66 μM. In addition, device response to interfering molecules is less than ±1 nA, and the spike‐and‐recovery test is successfully demonstrated.
Imaging of Love Waves and Their Interaction with Magnetic Domain Walls in Magnetoelectric Magnetic Field Sensors
Authors: Müller Cai , Durdaut Phillip , Holländer Rasmus B. , Kittmann Anne , Schell Viktor , Meyners Dirk , Höft Michael , Quandt Eckhard , McCord Jeffrey 
Published: May 2022

AbstractThe complex behavior of horizontally polarized surface shear waves in magnetoelectric surface acoustic wave based magnetic field sensor devices is revealed by time‐resolved magnetooptical microscopy with picosecond temporal and submicron spatial resolution. The imaging of the propagating waves in the magnetoelectric composites is realized through the functional soft‐magnetic layer by coupled magnetoelastic interactions. Partial surface wave reflections, wave front dephasing, and secondary wave generation occur, which originate from structures and magnetic domain walls. Closure domain structures bend and reflect the magnetic surface waves. Strain stimulated magnetic domain walls display dynamic periodic expansions, which propagate along the domain walls and change the magnetomechanical response also in the surrounding regions. The revealed spatial and temporally varying nondeterministic response restricts the noise performance of the surface acoustic wave based magnetic field sensors and thus confines the sensor's limit of detection. Magnetic time‐resolved optical imaging is shown to be a powerful method for the operando characterization of magnetoelectric devices and in‐plane displacement surface acoustic wave fields that are not accessible by other methods.
Productivity and water use of ratoon rice cropping systems with water‐saving, drought‐resistant rice
Authors: Xia Fangzhao , Wang Wukai , Weng Yulin , Ali Ihsan , Zhao Jinsong , Nie Zhongnan , Li Xinghua , Yao Xuan , Yang Tewu 
Published: May 2022

AbstractWater‐saving, drought‐resistant rice (WDR) (Oryza sativa L.) is a type of new rice cultivars with high drought resistance and low water consumption in the production phase. Ratoon rice cropping is regarded as a resource‐efficient rice production system with low cost and high profit. The development of ratoon rice system with WDR is conducive to the sustainable production of rice and the expansion of rice plantation; however, no such attempt has been made. In this study, a field experiment was conducted for 2 yr to evaluate the feasibility of developing new ratoon rice cropping systems using WDR compared with using common lowland rice (CLR). The productivity, regenerative capacity, and water use efficiency (WUE) were investigated in the water‐saving cultivation system using two WDR cultivars—Jieyou 652 and Jieyou 804—and in the conventional flooding cultivation system using the CLR cultivar Fengliangyouxiang 1. The irrigation WUE for the WDR systems was 89.8–214.8% and 243.4–765.6% higher than for the CLR system in the main and ratoon cropping seasons, respectively. The grain yield was not significantly different in the main cropping season between the WDR and CLR systems; nevertheless, it was lower in the WDR systems because of shorter growth duration and smaller panicles in the ratoon season. Higher accumulations of dry matter (DM), nonstructural carbohydrates (NSCs), and nitrogen in the stubble of main‐season crops is helpful to the promotion of regenerative capacity of WDR in the ratoon season.
Identification of key regulatory genes involved in the sporophyte and gametophyte development in Ginkgo biloba ovules revealed by in situ expression analyses
Authors: D'Apice Greta , Moschin Silvia , Nigris Sebastiano , Ciarle Riccardo , Muto Antonella , Bruno Leonardo , Baldan Barbara 
Published: May 2022

AbstractPremiseIn Arabidopsis thaliana, the role of the most important key genes that regulate ovule development is widely known. In nonmodel species, and especially in gymnosperms, the ovule developmental processes are still quite obscure. In this study, we describe the putative roles of Ginkgo biloba orthologs of regulatory genes during ovule development. Specifically, we studied AGAMOUS (AG), AGAMOUS‐like 6 (AGL6), AINTEGUMENTA (ANT), BELL1 (BEL1), Class III HD‐Zip, and YABBY Ginkgo genes.MethodsWe analyzed their expression domains through in situ hybridizations on two stages of ovule development: the very early stage that corresponds to the ovule primordium, still within wintering buds, and the late stage at pollination time.ResultsGBM5 (Ginkgo ortholog of AG), GbMADS8 (ortholog of AGL6) and GbC3HDZ1‐2‐3 were expressed in both the stages of ovule development, while GbMADS1, GbAGL6‐like genes (orthologs of AGL6), GbBEL1‐2 and YABBY Ginkgo orthologs (GbiYAB1B and GbiYABC) seem mostly involved at pollination time. GbANTL1 was not expressed in the studied stages and was different from GbANTL2 and GbBEL1, which seem to be involved at both stages of ovule development. In Ginkgo, the investigated genes display patterns of expression only partially comparable to those of other studied seed plants.ConclusionsThe expression of most of these regulatory genes in the female gametophyte region at pollination time leads to suggest a communication between the sporophytic maternal tissue and the developing female gametophyte, as demonstrated for well‐studied model angiosperms.
carba‐Nucleopeptides (cNPs): A Biopharmaceutical Modality Formed through Aqueous Rhodamine B Photoredox Catalysis
Authors: Immel Jacob R. , Bloom Steven 
Published: May 2022

AbstractExchanging the ribose backbone of an oligonucleotide for a peptide can enhance its physiologic stability and nucleic acid binding affinity. Ordinarily, the eneamino nitrogen atom of a nucleobase is fused to the side chain of a polypeptide through a new C−N bond. The discovery of C−C linked nucleobases in the human transcriptome reveals new opportunities for engineering nucleopeptides that replace the traditional C−N bond with a non‐classical C−C bond, liberating a captive nitrogen atom and promoting new hydrogen bonding and π‐stacking interactions. We report the first late‐stage synthesis of C−C linkedcarba‐nucleopeptides (cNPs) using aqueous Rhodamine B photoredox catalysis. We prepare brand‐newcNPs in batch, in parallel, and in flow using three long‐wavelength photochemical setups. We detail the mechanism of our reaction by experimental and computational studies and highlight the essential role of diisopropylethylamine as a bifurcated two‐electron reductant.
Evaluation of performance properties of poly(styrene‐co‐butadiene) rubber reinforced with N,N‐Dimethylacetamide/lithium chloride treated precipitated silica
Authors: Saleem R. Mohammed , Natchimuthu N. 
Published: May 2022

AbstractPrecipitated silica, treated with N,N‐Dimethylacetamide (DMAc)/Lithium Chloride (LiCl) at different LiCl concentrations, is used as reinforcing filler for poly(styrene‐co‐butadiene) rubber (SBR). DMAc/LiCl treatment of silica reduces hydrogen bonding within silica particles and improve its dispersion in rubber. Fourier transform‐infrared spectroscopy (FTIR) and X‐ray diffraction (XRD) data of treated DMAc/LiCl silica have indicated increased free hydroxyl groups as LiCl concentration in DMAc increases. Scanning electron microscopy (SEM) and Atomic force microscopy (AFM) investigations revealed smaller silica agglomerates, reduced scan height distribution and surface roughness. Better dispersion and reduced storage hardening of DMAc/LiCl treated silica‐filled SBR masterbatches, in the presence of bis‐(triethoxy silylpropyl)‐tetrasulphide (TESPT), are indications of easier processing of these compounds as observed from Mooney viscosity data. Mooney scorch time values at 125°C for compounds containing treated silica have indicated increased cure rates. Moving die rheometer data at 150°C have shown that combination of TESPT and DMAc/LiCl enhanced the processing safety of SBR compounds. Optimum concentration of LiCl combined with TESPT has resulted in enhanced crosslink density, physical properties, reduced swelling and heat build‐up in SBR vulcanizates.
Investigation of co‐electrospun gelatin:TiO2/polycaprolactone:silk fibroin scaffolds for wound healing applications
Authors: Golipour Hassan , Ezzatzadeh Elham , Sadeghianmaryan Ali 
Published: May 2022

AbstractElectrospinning is a facile technique to create porous nanofiber scaffolds with a high capability of natural environment mimicking. Here, co‐electrospinning of gelatin:TiO2, polycaprolactone:silk fibroin (G:T/P:F) was investigated with the aim of wound healing. Polycaprolactone improved the mechanical properties and gelatin:TiO2enhanced cellular interactions. Silk fibroin was extracted from theBombyx morisilkworm and increased the cellular and mechanical properties of the designed scaffolds. The morphology of the scaffolds was observed with field emission scanning electron microscopy (FESEM) and confirmed bead free porous nanofibrous structure. The fiber diameter rose after silk fibroin and TiO2addition but it was in the favorable fiber range. The contact angle, swelling, and mechanical properties of the G:T/P:F scaffolds supplied the requirements for skin tissue engineering. The designed scaffold showed over 80% cell viability with filopodia formation after 48 h according to cell adhesion observations and MTT assay results. The DAPI and LIVE/DEAD staining results confirmed high cell viability and the scratch assay observations proved the high wound healing potential of the G:T/P:F scaffolds. Furthermore, antibacterial properties were shown. It seems the designed scaffold can be useful in skin tissue regeneration. Further research may address the suggested skin scaffold.
Effect of phosphorylated lignin on flame retardancy of polypropylene‐based composites
Authors: Lee Jung‐Hun , Jang Dawon , Yang Inchan , Jo Seong Mu , Lee Sungho 
Published: May 2022

AbstractPolypropylene (PP) is a synthetic polymer with excellent physical properties useful for various industries. However, its flammability in air limits its applications. In the present work, lignin filler was modified by phosphorylation, and characterized through chemical, structural, thermal, and morphological analyses. The resultant products were incorporated into PP to increase the flame retardancy of PP‐based composites. Although, the mechanical properties of the PP composites containing 30 wt% filler deteriorated, the tensile strength was maintained. An addition of phosphorylated lignin (pL) into PP decreased the heat release rate from 1136.5 to 777.2 kW/m2 and the total smoke release from 25.1 to 9.6 m2/m2. Furthermore, scanning electron microscopy images of the pL incorporated composites after the combustion test revealed that the solid char formed on the composites acted as a protective layer for PP. Thus, incorporating pL into PP is a feasible approach for improving its flame retardancy.
Classifying papers into subfields using Abstracts, Titles, Keywords and KeyWords Plus through pattern detection and optimization procedures: An application in Physics
Authors: Pech Gerson , Delgado Catarina , Sorella Silvio Paolo 
Published: May 2022

AbstractClassifying papers according to the fields of knowledge is critical to clearly understand the dynamics of scientific (sub)fields, their leading questions, and trends. Most studies rely on journal categories defined by popular databases such as WoS or Scopus, but some experts find that those categories may not correctly map the existing subfields nor identify the subfield of a specific article. This study addresses the classification problem using data from each paper (Abstract, Title, Keywords, and the KeyWords Plus) and the help of experts to identify the existing subfields and journals exclusive of each subfield. These “exclusive journals” are critical to obtain, through a pattern detection procedure that uses machine learning techniques (from software NVivo), a list of the frequent terms that are specific to each subfield. With that list of terms and with the help of optimization procedures, we can identify to which subfield each paper most likely belongs. This study can contribute to support scientific policy‐makers, funding, and research institutions—via more accurate academic performance evaluations—, to support editors in their tasks to redefine the scopes of journals, and to support popular databases in their processes of refining categories.
An asymptotic state estimator design and synchronization criteria for fractional order time‐delayed genetic regulatory networks
Authors: Anbalagan Pratap , Hincal Evren , Ramachandran Raja , Baleanu Dumitru , Cao Jinde , Niezabitowski Michał 
Published: May 2022

AbstractThis paper mainly investigates the asymptotic state estimator design and impulsive controlled synchronization for fractional‐order time‐delayed genetic regulatory networks (FOTDGRNs). Different from the existing state estimator results, the asymptotic state estimator design of FOTDGRNs is studied by using a novel algebraic method, fractional‐order Lyapunov–Razumikhin method, and some famous inequality techniques. Afterward, a suitable impulsive controller is designed for the global asymptotic synchronization criteria for addressing master–slave systems. At last, the paper comes up with two numerical cases to justify the applicability of our theoretical outcomes.
Reliable control strategy based on sliding mode observer against FDI attacks in smart grid
Authors: Li Jian , Yang Defu , Su Qingyu 
Published: May 2022

AbstractThis paper is concerned with the reliable operation of cyber‐physical systems under false data injection attacks. First of all, a robust adaptive sliding mode observer is designed to estimate the state of the power system; different from the traditional sliding mode observer, the observer we designed is not only robust to state errors but also can automatically adjust the parameter of attack identification. Secondly, a method of attack reconstruction has been given to estimate the actual attack signal. Finally, a reliable sliding mode control strategy is proposed to eliminate the impact of false data injection attacks; compared with the existing results, the designed defense strategy utilizes the reconstructed attack signal in the attack identification scheme and state error signal at the same time. Moreover, a power system with 3 generator buses and 6 load buses is taken as an simulation example to verify the availability of the proposed control strategy.
The control methods of Knee‐Ankle‐Toe Active Transfemoral Prosthesis in stance phase
Authors: Geng Yanli , Wu Zhengen , Chen Yawei , Lin Bai , Xuan Bokai 
Published: May 2022

AbstractIn this paper, a Knee‐Ankle‐Toe Active Transfemoral Prosthesis (KATATP) is designed for improving the walking performance of the amputees. The main contents are as follows: First, the mechanical model of the prosthesis with three joints is established to help analyze the kinematics and dynamics characteristics of the joints; second, the Drive Torque Calculation cell is proposed to calculate the torque required for the movement of prosthesis joints; third, the motor, which provides the desired torque, drives the prosthesis; finally, experimental results indicate that the KATATP can help the amputee obtain more natural and symmetrical walking gaits. Moreover, the plantar pressure information of the amputated side is close to that of the sound side.
Single‐particle correlation study: Chemical interface damping in gold nanorods coated with mesoporous silica shell
Authors: Heo Seong Eun , Ha Ji Won 
Published: May 2022

AbstractChemical interface damping (CID) is the most recently suggested plasmon damping pathway induced by adsorbate molecules in gold nanoparticles. Despite recent advances in this field, CID has not been studied in gold nanorods coated with mesoporous silica shells (AuNRs@mSiO2). Herein, we conducted a single‐particle correlation study to elucidate CID using p‐nitrothiophenol (p‐NTP) as adsorbates in single AuNRs@mSiO2. Through surface‐enhanced Raman spectroscopy studies, we confirmed that p‐NTP with a strong electron‐withdrawing group was effectively adsorbed on the AuNR cores. Following the chemisorption of p‐NTP, a strong CID was observed with localized surface plasmon resonance (LSPR) linewidth broadening through the preferred interaction between sulfur and the Au surfaces. Furthermore, we presented the molecular binding effect on the LSPR linewidth of single AuNRs@mSiO2 during the reaction with p‐NTP in real‐time. Thus, the result further supported that the CID could be used to develop LSPR sensors having low sensitivity to the medium dielectric constant.