bluuebunny/crossref_metadata_2025_split huggingface dataset:
Immunological Examination of Echinococcus granulosus as a Candidate for Cancer Treatment and Vaccine Development: A Review Study
Authors: Shooraj Mahdi , Hajipour Elahe , Mahdavi Seif Ali 
Published: September 2022

Echinococcus granulosus, is a cestode parasite that causes cystic echinococcosis. The vaccination procedure with tumor-associated antigens, coming from evolutionary distant organisms such as parasites, can be beneficial to override tolerance problems encountered with human tumor-associated antigens-based cancer therapeutic approaches. In this article, different databases of PubMed, Google Scholar, IranDoc and SID were examined from 2001 to 2021 and related articles were investigated. The review of related studies concerning human beings' treatment revealed the possibility of inhibition of cancer development via HCF antigens and mucin peptides extracted from this cestode. Besides, HCF treatment in animal models mostly showed that anti-cancer immune responses were activated. Of note, an influential issue in the design process of an anti-cancer vaccine is triggering efficacious anti-tumor responses by using idyllic antigens for immunization against cancer. In this realm, many antigens have been studied for this purpose and showed different ranges of effectiveness. Based on the cross-reactivity among parasitic and tumor antigens, detection of parasitic antigens that are highly homologous with cancer antigens is an ideal objective for immunization against cancer cells. As the toxicity of HCF was reported in some studies, further research are required to shed light on finding an innovative anti-cancer vaccine derived from parasites. This review article is useful for health managers and researchers working on the anti-cancer vaccine development.
Building ESL Learners’ Digital Literacy Skills Using Internet Memes
Authors: Nguyen Hanh , Chambers Wendy , Abbott Marilyn 
Published: September 2022

Digital literacy skills are crucial twenty-first-century skills that are required for the successful use of technology and active engagement in today's world. However, there is a lack of effective resources and guidelines for developing English as a second language (ESL) learners’ digital literacy skills. Due to their increasingly important and influential role in contemporary society, Internet memes hold great potential for language teaching and learning, particularly given their infectious nature. Internet memes are digital compositions that convey concepts and ideas via a variety of media types, including image, text, audio, and video. In this article, we describe the characteristics and value of memes as a digital resource and explore the ways in which memes can be used to enhance ESL learners’ digital skills. Pegrum et al.’s digital literacies framework provides the lens to both examine memes and inform the development of a detailed guide that teachers can use when selecting appropriate memes for use in the ESL classroom. We also provide an exemplar task for using memes to build intermediate ESL learners’ language and digital literacy skills based on the guide and include links to some useful websites for meme resources and meme-related activities.
Les compétences en littératie numérique constituent des compétences cruciales du 21e siècle qui sont essentielles pour utiliser la technologie avec succès et s’engager activement dans le monde d’aujourd’hui. Cependant, il existe un manque de ressources efficaces et de lignes directrices pour développer les compétences en littératie numérique des apprenants de l’anglais langue seconde (ALS). En raison de leur rôle important et croissant dans la société contemporaine, les mèmes de l’Internet représentent un grand potentiel pour l’apprentissage et l’enseignement des langues, particulièrement à cause de leur nature contagieuse. Les mèmes sont des œuvres numériques qui transmettent des concepts et des idées à travers des types variés de médias, y compris l’image, le texte, l’audio et la vidéo. Dans cet article, nous décrivons les caractéristiques et la valeur des mèmes en tant que ressources numériques et nous explorons leurs utilisations potentielles pour promouvoir les compétences numériques des apprenants. Nous utilisons le cadre des compétences numériques de Pegrum et al pour examiner les mèmes et soutenir l’élaboration d’un guide détaillé sur lequel les enseignants pourraient s’appuyer pour sélectionner les mèmes appropriés pour une classe d’ALS. Nous présentons également une tâche modèle, basée sur le guide, pour l’utilisation des mèmes dans la promotion des compétences langagières et de littératie numérique d’apprenants intermédiaires d’ALS. De plus, nous suggérons des liens de sites web utiles contenant des ressources sur les mèmes et des activités liées aux mèmes.
Between Waves: LINC Instructors’ Perspectives on Pandemic Teaching
Authors: Detwyler Dmitri 
Published: September 2022

The 2020 outbreak of the global COVID-19 pandemic imposed emergency remote teaching on adult English as a second language (ESL) programs globally, creating unprecedented challenges not only for language learners but also for instructors. Immense difficulties were produced in the collision between a biological hazard (the novel coronavirus) and the power-inflected social structures that organize language teaching in different locales. In this paper I explore some impacts of the pandemic on three instructors in the single largest adult ESL program in Canada, Language Instruction for Newcomers to Canada (LINC). Grounded in an account of the historical origins and development of the LINC program, a reflexive thematic analysis of instructor responses to vignettes of resonant challenges identified three major issues that were intensified by the pandemic: navigating digital inequities, balancing the teaching of digital literacies and language teaching in an accountability framework, and managing boundaries and expectations. These results are contextualized in the larger conversations around LINC and adult ESL programming globally, and some implications and new directions for the post-pandemic landscape now visible on the horizon are also considered.
L’éclosion de la pandémie globale COVID-19 a imposé d’urgence l’enseignement à distance sur les programmes d’enseignement de l’anglais langue seconde (ALS) partout dans le monde, créant ainsi des défis sans précédent pour les apprenants de langues et leurs enseignants. Des difficultés considérables ont résulté de l’intersection explosive entre un danger biologique (le nouveau coronavirus) et les structures sociales basées sur le pouvoir qui organisent l’enseignement des langues dans plusieurs endroits. Dans cet article, j’explore certaines répercussions de la pandémie sur trois enseignants dans le plus grand programme d’enseignement de l’ALS aux adultes au Canada, le programme CLIC (Cours de langue pour les immigrants au Canada). Basée sur un récit des origines historiques et du développement du programme CLIC, l’analyse thématique réflexive des réponses des enseignants à des vignettes illustrant des défis évocateurs a identifié trois enjeux majeurs qui ont été intensifiés par la pandémie : naviguer les inégalités numériques, assurer l’équilibre entre l’enseignement des littératies numériques et l’enseignement de la langue dans un cadre responsable et gérer les limites et les attentes. Ces résultats sont contextualisés dans une discussion plus large sur le programme CLIC et les programmes d’enseignement d’ALS aux adultes autour du monde. Certaines implications et nouvelles directions pour le contexte postpandémie, désormais visible à l’horizon, seront également discutées.
The Workplace Writing Experiences of EAL Professionals
Authors: John Cheryl 
Published: September 2022

A review of the literature on English second language (L2) writing skills reveals a need for more research on the workplace writing experiences of L2 professionals employed in English as an additional language (EAL) contexts. Through a semi-structured interview and a think-aloud activity, this study gathered qualitative data with the aim of gaining insight into the workplace writing practices, challenges, and strategies of five EAL professionals with developing workplace writing skills, employed in Toronto. The data were initially analyzed using a thematic analysis technique, and upon further exploration, three factors were identified as influential in the development of the participants’ workplace writing skills: motivation, awareness of the role of self, and awareness of the role of others.
Une revue de la littérature sur les compétences d’écriture en anglais langue seconde (ALS) révèle la nécessité de mener davantage de recherches à propos des expériences d’écriture dans le milieu de travail des professionnels ayant appris l’ALS et qui travaillent dans des contextes d’anglais en tant que langue additionnelle (ALA). En utilisant des entretiens semi-dirigés et des activités de réflexion à haute voix, cette étude qualitative avait pour objectif de mieux comprendre les pratiques, défis et stratégies d’écriture en milieu de travail de 5 professionnels ALA, ayant des compétences d’écriture en développement et travaillant à Toronto. Les données ont été initialement analysées suivant une technique d’analyse thématique. Des analyses plus approfondies ont mené à l’identification de trois facteurs d’influence dans le développement des compétences d’écriture en milieu de travail chez les participants : la motivation, la conscience du rôle de soi-même et la conscience du rôle des autres.
Special Issue on Recent Progress in Manufacturing Technology
Authors: Narahara Hiroyuki , Gao Feng 
Published: September 2022

The continued effects of the global spread of COVID-19 have reaffirmed that restrictions on the movement of people and products have geopolitical consequences. In addition, the impacts involved in the decarbonization of the global environment have further strengthened the growing demand for the building of a sustainable society. These factors have had no small impact on the global economy and on global manufacturing as well. In this context, the demand for the realization of new manufacturing technologies that can respond to changes in social and economic environments has been growing.
This special issue focuses on recent advances in manufacturing technologies that maximize product quality and reduce costs, with an emphasis on the machinery industry. This special issue of the IJAT contains 12 papers. These include works on cutting technology, machining metrology, advanced machine tools, gear manufacturing technology, additive manufacturing, and more. The first five papers are proposals for new cutting technologies and elucidations of cutting phenomena. The next three papers are new proposals for machining measurements. The next two papers are on precision positioning technologies and a rack gear compensation technology. The last two papers are theoretical investigations into the basic phenomenon of additive manufacturing and its applications.
These papers were originally presented at the 10th International Conference on Leading Edge Manufacturing in the 21st Century (LEM21), held in Kitakyushu, Japan in 2021. The papers have been revised and expanded at the request of the editors.
The editors would like to thank all authors for their comprehensive efforts in making this special issue possible, and would like to thank the anonymous reviewers for their hard work. We wish them all the best in their future research in this field of manufacturing technology.
Hypocortisolism in attention deficit hyperactivity disorder – roles of sex, comorbidity, and symptom presentation
Authors: Pauli-Pott Ursula , Skoluda Nadine , Nater Urs M. , Becker Katja , Derz Friederike , Kaspar Elena , Kasperzack Daria , Kehm Kira , Kött Marie , Mann Christopher , Schurek Pia , Pott Wilfried , Schloß Susan 
Published: September 2022

Abstract
Objective: Low activity of the hypothalamic-pituitary-adrenal axis (HPAA) has been found in children with ADHD. The condition may be related to the reduced attention regulation capacity and/or to comorbid oppositional defiant or conduct disorder (ODD/CD). Sex differences are probable but not sufficiently studied. We analyzed hypocortisolism and the reactivity of the sympathetic nervous system (SR) in boys and girls with ADHD and healthy controls. Methods: The sample comprised 205 children (98 with ADHD and 107 healthy controls). DSM-5 phenotypic symptom presentation and comorbid ODD/CD were assessed using clinical interviews. Hair cortisol concentration (HCC) was used to assess the long-term, cumulative activity of the HPAA. SR was assessed via skin conductance response (SCR). For control purposes, comorbid internalizing symptoms and indicators of adverse childhood experiences were assessed. Children were medication naive.Results: Boys presenting with predominantly inattentive symptoms (ADHD-I) showed lower HCC than did healthy boys. Girls presenting with combined symptoms (ADHD-C) showed higher HCC than did healthy girls (p’s<.05, sex-by-group interaction, F(2,194)=4.09, p=.018). Boys with ADHD plus ODD/CD showed a blunted SR (p<.001, sex-by-group interaction, F(2,172)=3.08, p=.048). Conclusion: HCC constitutes an easily assessable, reliable, and valid marker of phenotypic ADHD-related features. It indicates more homogenous subgroups of ADHD and might point to specifically involved pathophysiological processes.
The effect of exogenously induced magnetic fields on neurotransmitter dynamics
Authors: Rivas Manuel , Martinez-Garcia Marina 
Published: September 2022

Abstract
Over the past decades, there has been significant controversy regarding the role of exogenous electromagnetic (EM) fields on the dynamics of molecules in living cells. Here we present a model of electromagnetic forces in the synaptic cleft using the bidomain theory as a framework and the averaged field theory as the theoretical basis, suggesting that the exogenously induced magnetic field may modify the neurotransmitter dynamics. Our model is based on a voltage cell membrane amplification due to the Hall effect principle and the hypothesis that synaptic cleft electric conductivity is represented by tensors with non-zero off-diagonal terms. The physical interpretation of the off-diagonal components is explained, and analytical expressions for the induced magnetic field and conductivity tensor are derived.
Multivariate analysis of multiscale periodicity in North American annual mean sea level based on wavelet coherence and multiple wavelet coherence
Authors: Song Chao , Chen Xiaohong 
Published: September 2022

Abstract
The relationships between sea levels and single climate indexes have been widely explored. However, sea level is controlled by multiple climate factors simultaneously with differences among places and time scales. Despite this, few studies have addressed the relationships between sea levels and multiple climate indexes. Here, the interrelations between the annual mean sea level (AMSL) and individual climate indexes and combinations of climate indexes were characterized by wavelet coherence (WTC) and multiple wavelet coherence (MWC). The results showed that six climate indexes had a significant correlation with AMSL, among which the Atlantic Multidecadal Oscillation (AMO) had the least significant correlation, but Niño3.4 had the significant correlation. The average significant coherence area (PASC) value for Niño3.4 was 14.03% and its average wavelet coherence (AWC) value was 0.79. By combining climate indexes, the average values of PASC and AWC can be significantly increased. The average PASC and AWC values of the five climate index combinations were the largest, 95.87% and 0.965, respectively, followed by four, three, and two index combinations. A single climate index is not sufficient to explain sea level change in North America. Sea level changes in North America require between three and five climate indexes to explain, depending on the region. By calculating PASC and AWC values, this study provides the possibility to understand the impact of the combined effects of multiple climate indexes on AMSL, is of great help to screen the best predictor of sea level, and provides a new method to reveal the complex mechanism of sea level change.
Sap flux and stable isotopes of water show contrasting tree water uptake strategies in two co-occurring tropical rainforest tree species
Authors: Sohel Md. Shawkat I. , Herbohn John , McDonnell Jeffrey 
Published: September 2022

Little is known about the short‐term dynamics of tree water use
strategies particularly for neighbouring co-occurring species. Here, we
quantify the high frequency changes in water sources and sap ﬂux
patterns of two commonly co-occurring tropical rainforest tree species:
Dendrocnide photinophylla (Kunth; Chew) and Argyrodendron
peralatum (F.M. Bailey; Edlin ex J.H. Boas). A combination of
continuous sap flux measurements and hourly sampling of xylem water
stable isotope composition (δDand δ O) were used to
observe water use strategies through a 24 h transpiration cycle. Sap
flux ranged from 2.82-28.50 L d and was 66.67%
higher in A. peralatum compare to D. photinophylla. For
both tree species, sap flux increased with tree size and diurnal sap
flux increase resulted in more isotopically enriched xylem water. A
Bayesian Mixing Model analysis using sampled soil water isotopic
composition from five soil depths from of 0 to 1 m showed that D.
photinophyllaused very shallow or surface layer (0-20 cm) water, while
A. peralatum sourced its water mostly from deeper in the soil
profile (>20 cm). We hypothesize that these differences in
species’ water consumption patterns are reated to plant water storage
capacity and, wood anatomical features. Our study shows that combning
xylem isotope composition and sap flux measurements can help reveal
species level water use strategies—useful for improved process
understanding for ecohydrological modeling.
Private Information Acquisition via Freedom of Information Act Requests Made to the Securities and Exchange Commission
Authors: Glaeser Stephen , Schonberger Bryce , Wasley Charles E. , Xiao Jason J. 
Published: September 2022

ABSTRACT
There is limited evidence about when, why, and which individuals incur costs to acquire nonpublic information about a firm, largely due to the difficulty of observing private information acquisition. To overcome this difficulty, we obtain data on Freedom of Information Act (FOIA) requests submitted to the Securities and Exchange Commission (SEC). We predict and find that perceived information asymmetry between managers and outsiders resulting from both proprietary and agency costs triggers FOIA search. We categorize organizations making FOIA requests using their business descriptions and find that many, including law and intellectual property firms, are not expressly interested in obtaining information for near-term equity trading. Instead, their search activity relates to determinants beyond financial characteristics, including patent litigation and executive turnover. Taken together, we provide evidence on private information search by a relatively unexamined set of organizations and shed new light on the function of the SEC’s Office of FOIA Services.
JEL Classifications: D82; D83; M41.
Healing from Healer: Use of Traditional Health Services in the Age of Modern Health
Authors: Syaiful Muhammad , Hakim Arif Rahman , Hak Imamul 
Published: September 2022

The phenomenon of traditional health practices is still being used by some people, the unique thing is that those who take advantage of this health service do not only come from underprivileged segments of society but are also often used by the rich. Moreover, this phenomenon occurs during the existence of a modern health industry whose access is increasingly accessible to all people. Traditional medicine or so-called alternative medicine that uses plant-based medicines (herbal) or other media. Not only in the area of medicine, but this research also describes traditional healers or as local, sanro, as an alternative to modern health industry practices. This study uses an ethnographic method with a participatory-observative approach to understanding in-depth the practice of alternative medicine. Field research focus in the district. Somba Opu, Gowa Regency, South Sulawesi. Where the distribution of modern health facilities in the capital of this sub-district is higher than in other sub-districts. The results of the study indicated that the medical instruments performed by traditional healers, apart from using traditional herbs in the form of special plants, also used mantras written in the book using Arabic letters. Some of the traditional medicinal methods in maintaining their existence are carried out, both in the form of good health services, trying to prove the efficacy of the treatment, and strengthening their networks with doctors and fellow sanro outside the District of Gowa.
Sanitation Environment and Helminth infection in Gowa District, Indonesia
Authors: Syamsul Muharti , Kartini Kartini , Aswadi Aswadi , Syamsul Muhammad Azrul 
Published: September 2022

Healminth infection is one of the environmentally-based diseases which is a problem for public health. This research was conducted to know the description of latrines, trash bins, and clean water victims for people with healminth infection in the working area of the Kanjilo Health Center. This research uses quantitative research methods with a descriptive survey approach. The research sample was 32 samples. The data used are preliminary data from the medical records of the Kanjilo Health Center, Gowa Regency, while the data source used is secondary data. Data analysis using data processing research with SPSS. With a frequency distribution approach. The results showed that the worms that occurred were in a bad category, including 8 respondents who vomited worms and 24 who suffered from healminth infection. The results of this study found that both the availability of latrines, the availability of clean water and landfills, were all in the bad category, causing worms and vomiting in the community in the working area of the Kanjilo Health Center.
Altitude Factors Affect Dengue Fever Cases in South Sulawesi: A Study Using Poisson Inverse Gaussian Regression Model
Authors: Adiatma Adiatma , Tohari Amin , Faisal Ali , Alam Syamsul 
Published: September 2022

Poisson regression is used to model enumeration data such as data on the number of DHF cases. This model has the assumption that is fulfilled is the average and the variance must have the same value or it is called the equidispersion. But this assumption is not fulfilled because the data on the number of dengue cases experienced violations of this assumption. The violation is that the average value is smaller than the variance value or it is called overdispersion. This results in incorrect conclusions because the prediction standard error is underestimated. The way to prevent this is by combining the Poisson distribution and discrete or continuous distribution, this combination is called Mixed Poisson Distribution. Researchers use one of the Mixed Poisson methods, namely Inverse Gaussian Poisson Regression (PIG) because the method is used when the data is overdispersed and the parameters are known or close form on the likelihood function. Based on the results of the study, it is known that the height of the area is a factor that significantly influences DHF cases in South Sulawesi.