bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tuberous Sclerosis And Kidney Failure - A Case Report
Authors: Labovic Boban , Rabrenovic Violeta , Rabrenovic Milorad , Petrovic Milica , Dulovic Dragan , Rakonjac Aleksandar , Pilcevic Dejan , Petrovic Marijana , Tadic Jelena 
Published: March 2022

Abstract

Introduction: Tuberous sclerosis (TS) is a rare systemic autosomal- dominant genetic disease in which multiple hamartomatous lesions occur in many organs and tissues. Kidney involvement of TS usually includes angiomyolipomas, cysts, rarely kidney tumors, but there is not much description of other kidney involvement (proteinuria, hematuria, advanced kidney failure). We present a patient with preterminal renal failure who is diagnosed with tuberous sclerosis.

Case report: A 52-year-old female was admitted to the hospital, due to decreased kidney function with worsening of the general condition and crises of consciousness. During the examination, cutaneous lesions -facial angiofibrolipomas were noticed, the patient was dehydrated and pale. Laboratory analyzes showed elevated parameters of nonspecific inflammation, anemic syndrome, azotemia (Cr 578umol / l, urea 50.1mmol / l, CKD e GFR 10 ml / min / 73m2), leukocyturia, microerythrocyturia, proteinuria 1.5 g / 24h. MSCT of the abdomen indicated hemangiomas of the liver, enlarged kidneys with several hypodense and hyperdense changes - angiomyolipomas. Due to the crisis of consciousness, MSCT of the head was performed, on which cysts and calcifications of the brain were observed. During the treatment, there was a confusing state, agitation, and epilepsy seizure. MRI brain showed multi locular brain cysts with ependymal and subependymal calcified nodules in the lateral ventricles. The applied treatment resulted in a partial recovery of kidney function (CKDeGFR 17 mil / min / 1.73 m2, and further approach in the monitoring and treatment of this patient was multidisciplinary. Chronic renal failure of 4 stages was maintained for a further six-month follow-up.

Conclusion: We underline the importance of a multidisciplinary approach in the treatment of patients, bearing in mind that, as in our patient, a rare genetic disease - tuberous sclerosis can be manifested by kidney failure of preterminal rank.
The influence of student’s perceptions on online learning and independent learning on employability skills F&B service in the culinary expertise Program of Vocational High School
Authors: Aini Annisa Nur , Ismawati Rita , Handajani Sri , Marniati Marniati , Rijanto Tri 
Published: March 2022

Employability skills are work skills that refer to general or non-technical competencies which include achievement, understanding and personal attributes that enable a person to get a job and be successful in the job of their choice. employability skills can be formed from learning methods and student learning independence. The application of the learning method currently used is online learning due to the Covid-19 pandemic. This study aims to determine the influence of student perceptions on online learning and independences learning on employability skills f&b service in the culinary expertise program of vocational high school. This is a quantitative of research with the type of expost facto research. Research method functions to examine specific populations or samples, data collection using questionnaire survey with the aim of testing predetermined hypotheses. The statistical data is multiple linear regression analysis and the hypothesis test are using T test and F test. The results are there is a significant contribution between perceptions of online learning and independent learning together on employability skills F&B Service in the Culinary Expertise Program of Vocational High School with a contribution value of 40.5%.
Nanoemulsion de liberación controlada de ibuprofeno con lecitina de soya
Authors: Bonilla Pablo , Bonilla Mariel 
Published: March 2022

En el presente trabajo se elaboraron nano-emulsiones de tipo O/W a partir de lecitina de soya, agua y mezclas de aceites de soya, maíz, canola y girasol; estas formulaciones se estudiaron para determinar su eficacia como medio de transporte de un fármaco lipofílico. Se solubilizó previamente la mayor cantidad de fármaco modelo en la fase oleosa, para la fase acuosa se utilizó agua tipo I; como surfactante se utilizó lecitina de soya grado alimenticio. Para la elaboración de las nano-emulsiones se utilizaron métodos de alta energía como agitación Vortex, homogeneizador Ultra Turrax y ultrasonido. Para caracterizar las nano-emulsiones se utilizaron un equipo de dispersión de luz dinámica (DLS), el cual permitirá medir el tamaño de gota, además para determinar la estabilidad se midió el potencial Z de la nano-emulsión, también se realizaron observaciones al microscopio y determinación del tamaño de gota en el Microscopio de Fuerza Atómica (AFM). Se realizaron pruebas de liberación del fármaco en un equipo de disolución acoplado con un espectrofotómetro UV-vis, que se utilizó para encontrar la cinética de liberación de la forma farmacéutica elaborada comparándola con estándares comerciales. La mejor formulación fue la realizada con la mezcla de aceites de soya/girasol, identificada como IS2TB, el ensayo de liberación de esta formulación dio el mayor porcentaje de liberación del principio activo con una cinética de liberación controlada.
Activation of ZnCl2 and KOH Carbon from Bark of Salak Wedi as a Material for Making Supercapacitor Electrodes
Authors: Ardianti Aprillia Dwi 
Published: March 2022

An activated carbon is a potential material that can be used as electrodes in super capacitors. It has a higher energy density than batteries and fuel cells, and a higher power density than conventional capacitors. This study was carried out by using activated carbon from the bark of salak wedi with various graded activators such as ZnCl2 and KOH. The physical characteristics of the activated carbon from the bark of salak wedi were analyzed using a Scanning Electron Microscope (SEM) to see its powder morphology. While, X-ray diffraction (XRD) is used to examine the structure of the bark of activated carbon that that has the potential to make electrodes of super capacitors . The results of SEM with graded activation had fewer pores, were not evenly distributed and tended to agglomerate compared to the activated carbon sample of salak bark which was activated once
Meta – Analisis: Peningkatan Kemampuan Berpikir Kritis Siswa melalui Implementasi Pembelajaran Kontekstual
Authors: Erlina Anggi Putri Novia , Widodo Suryo , Handayani Aprilia Dwi 
Published: March 2022

Kemampuan siswa dalam berpikir kritis yang meningkat melalui implementasi pembelajaran kontekstual menjadi topik kajian dalam penelitian ini. Pembelajaran kontekstual melatih siswa untuk menemukan esensi/makna konsep matematika yang dipelajari. Dengan demikian, melalui pembelajaran kontekstual, siswa mampu memahami keterkaitan antar konsep serta penerapannya pada kehidupan. Data penelitian ini diperoleh dari jurnal atau artikel yang relevan dengan pembelajaran kontekstual sebanyak sepuluh artikel. Penelitian ini menggunakan metode pembanding kuantitatif. Setelah dilakukan analisis, hasil yang diperoleh adalah implementasi pembelajaran kontekstual efektif diterapkan untuk dalam upaya peningkatan critical ability siswa mulai dari peningkatan terendah sebesar 6,96% sampai dengan yang paling tinggi sebesar 69,36% dengan rata – rata peningkatan sebesar 40,70%.
Menentukan Waktu Optimal untuk Pembuatan Kerajinan Sulaman Karawo Menggunakan Aljabar Max-Plus
Authors: Yahya Lailany , Nurwan Nurwan , Resmawan Resmawan 
Published: March 2022

Kerajinan Karawo merupakan salah satu kerajinan khas Gorontalo. Proses pembuatannya membutuhkan waktu yang sangat lama, mulai dari penyediaan bahan baku dan alat, pembuatan atau persiapan motif, pemotongan, pengaturan motif, mencabut benang, menyulam, merawang/ penenunan dan penyelesaian akhir. Dalam penelitian ini, metode aljabar max-plus digunakan untuk menentukan waktu optimal dalam membuat kerajinan sulaman karawo. Aktivitas pembuatan kerajinan sulaman karawo didesain dalam diagram kemudian ditransformasi dalam matriks max-plus. Berdasarkan matriks diperoleh , hal ini menggambarkan bahwa waktu optimum pembuatan kerajinan sulaman karawo adalah 34,5 hari.
Sağlık Çalışanlarının Afiliasyon Uygulamasına Yönelik Tutumlarının Araştırılması: Kırşehir ve Bolu Örneği
Authors: TOPÇU Tuğçe , ÖZATA Musa 
Published: March 2022

Araştırmanın amacı, afiliye olmuş olan T.C. Sağlık Bakanlığı Kırşehir Ahi Evran Üniversitesi Eğitim Araştırma Hastanesi ve T.C. Sağlık Bakanlığı AİBÜ İzzet Baysal Eğitim Araştırma Hastanesinde görev yapan sağlık çalışanlarının afiliasyon uygulamasına yönelik tutumlarının belirlenmesidir.
Çalışmada nicel araştırma yöntemine başvurulmuştur. Çalışmanın evrenini T.C Sağlık Bakanlığı Kırşehir Ahi Evran Üniversitesi Eğitim ve Araştırma Hastanesinden 965 sağlık çalışanı, T.C Sağlık Bakanlığı AİBÜ İzzet Baysal Eğitim ve Araştırma Hastanesinden ise 820 sağlık çalışanı oluşturmaktadır. Araştırmaya katılmayı kabul eden 415 sağlık personeline yüz yüze anket uygulanmıştır. Araştırmadan elde edilen verilerin analizi SPSS 22.00 paket programıyla yapılmıştır. Araştırmada güvenilirlik analizi, açımlayıcı faktör analizi, bağımsız gruplar arası t testi, tek yönlü varyans analizi ve ki-kare testi yapılmıştır.
Araştırma sonucunda afiliasyon sisteminden memnuniyet düzeyinin hastaneler açısından farklılık gösterdiği belirlenmiştir. Kırşehir Ahi Evran Üniversitesi çalışanlarının memnuniyet düzeyinin Bolu Abant İzzet Baysal Üniversitesi çalışanlarına göre; Sağlık Bakanlığı çalışanlarının memnuniyet düzeyinin üniversite çalışanlarına göre daha düşük olduğu belirlenmiştir. Sosyo-demografik özellikler açısından incelediğinde ise; hastane, bağlı olunan kurum, öğrenim durumu, meslek ve aylık gelir ile ölçek puanları arasında istatistiksel açıdan anlamlı bir fark tespit edilirken; cinsiyet, medeni durum, toplam çalışma süresi ve hastanedeki çalışma süresi ile ölçek puanları arasında istatistiksel açıdan anlamlı bir fark tespit edilememiştir.
Sporda Teknoloji Kullanımı: Bir Metafor Çalışması
Authors: YILDIZ Aydıner Birsin , ALGÜN DOĞU Gözde 
Published: March 2022

Teknolojinin günümüzde her alanda olduğu gibi spor faaliyetlerinin öncesinde, sırasında ve sonrasında birçok şekilde ve amaçla kullanılmasının, sporun öznesi olan sporcular tarafından nasıl değerlendirildiği merak konusu olmuştur. Bu çalışma sporcuların, spor bünyesindeki teknoloji kullanımına dair görüşlerini metaforlar aracılığıyla tespit etmek amacıyla yapılmıştır. Bu amaç doğrultusunda çalışma grubu farklı branşlarda aktif spor yapan 50 elit sporcudan oluşturulmuştur. Nitel araştırma yöntemlerinden olgu bilim deseninin kullanıldığı araştırmada veriler içerik analizi tekniği kullanılarak çözümlenmiştir. Katılımcıların sporda teknoloji kullanımına dair görüşlerini anlamak için “Sporda teknoloji kullanımı .... gibidir / ‘na benzer.
Çünkü ....” cümlelerini tamamlamaları istenmiştir. Sporda teknoloji kullanımına ilişkin antrenman, anne, antrenör, oksijen, ilaç, su gibi metaforlar tespit edilmiştir. Araştırma kapsamında elde edilen bu metaforlar “zorunluluk, fayda, rehber, adalet sağlama, tamamlayıcı olma” kavramsal kategorileri altında toplanmıştır. Bu araştırma kapsamında elde edilen metaforlar değerlendirildiğinde, elit sporcuların sporda teknoloji kullanımına dair olumlu bir tutum içerisinde olduğu ve sporcuların teknoloji kullanımını destekledikleri kanaati oluşmuştur.
PREFERENSI PENGELOLA BADAN USAHA MILIK DESA (BUMDes) TERHADAP PENERAPAN PRODUK KEUANGAN SYARIAH (STUDI PADA BUMDes DI KECAMATAN TAMBANG)
Authors: Hertina Hertina , Lubis Haniah , Khairunisa Madona , Nurnasrina Nurnasrina 
Published: March 2022

Tambang District with a Muslim majority population, it is certain that the people of Tambang District are easier to accept Islamic values ​​and principles in carrying out BUMDes management activities that they manage. The purpose of this study is to find out the preferences of Village Owned Enterprises (BUMDes) managers towards the application of Islamic financial products, as well as the supporting and inhibiting factors for the application of Islamic financial products in the management of BUMDes in Tambang District. This research is field research, and the data analysis in this study uses descriptive qualitative analysis. The results showed that the preference of BUMDes managers towards the application of Islamic financial products in Tambang District viewed from the social, individual and sociological aspects was very good and strong. Supporting factors for the implementation of Islamic financial products are government support and managers' perceptions. Meanwhile, the inhibiting factor is technical problems after the system changes from conventional and sharia systems.
Keyword: preference,Village Owned Enterprises (BUMDes), Islamic financial products
Analisis Pengembanagan Kantor Pelayanan, Penyuluhan, Dan Konsultasi Perpajakan (Kp2kp) Menjadi Kantor Pelayanan Pajak Mikro Dalam Melakukan Intensifikasi Pajak
Authors: Sukma Aliyudin Rizal , Fauziah Ahmad Eva 
Published: March 2022

Perubahan fungsi Kantor Pelayanan, Penyuluhan dan Konsultasi Perpajakan (KP2KP) menjadi Kantor Pelayanan Pajak Mikro (KPP Mikro) dalam prakteknya memiliki fungsi dan tugas berbeda, dimana dalam hal ini tugas dari KPP Mikro lebih luas, dan KPP Mikro diharapkan diharapkan dapat memberikan pelayanan yang lebih optimal.
Hasil penelitian ini diharapkan dapat bermanfaat dan memberikan tambahan bukti empiris dan pengetahuan mengenai teori-teori Perpajakan dan perkembangannya serta penerapannya dalam perubahan fungsi dan tugas KP2KP menjadi KPP Mikro dengan Intensifikasi pajaknya. Sebagai salah satu acuan yang dapat digunakan sebagai referensi untuk penelitian-penelitian di masa yang akan datang, terutama bagi penelitian-penelitian akuntansi terutama dalam sektor perpajakan.
Metodologi penelitian yang digunakan dalam penelitian ini adalah metode kualitatif. Penelitian kualitatif merupakan penelitian yang menghasilkan dan mengolah data yang sifat nya deskriptif, seperti transkripsi wawancara, catatan lapangan, gambar, foto, rekaman video, dan lain sebagainya (Poerwandari,1998:29).
Pengaruh Pengetahuan Akuntansi Syariah Dan Pertimbangan Pasar Kerja Terhadap Minat Mahasiswa Akuntansi Berkarir Di Lembaga Keuangan Syariah
Authors: Robi Maulana M  
Published: March 2022

Penelitian ini bertujuan untuk mengetahui pengaruh pengetahuan akuntansi syariah dan pertimbangan pasar kerja terhadap minat mahasiswa akuntansi berkarier di lembaga keuangan syariah
Metode yang digunakan yaitu metode survey dengan menggunakan teknik analisis deskriptif dan verifikatif. Sampel pada penelitian ini sebanyak 70 orang mahasiswa akuntansi semester VII yang telah lulus mata kuliah akuntansi syariah dengan menggunakan metode teknik random sampling dengan rumus slovin. Metode pengumpulan data primer yang dipakai adalah metode survei dengan menggunakan media kuisioner. Pengujian instrumen data dilakukan dengan uji validitas dan uji reliabilitas, uji asumsi klasik, sedangkan analisis datanya adalah analisis koefisien regresi berganda dan uji hipotesis.
Hasil ini menunjukan bahwa pengetahuan akuntansi syariah berpengaruh positif signifikan terhadap minat mahasiswa akuntansi berkarir di lembaga keuangan syariah, sedangkan pertimbangan pasar kerja berpengaruh positif signifikan terhadap minat mahasiswa akuntansi berkarir di lembaga keuangan syariah.
Pemilihan Karir Sebagai Akuntan Pada Perspektif Penghargaan Finansial Dan Personalitas
Authors: Yogi Ginanjar  
Published: March 2022

Pemilihan sebuah karir bagi mahasiswa akuntansi adalah tahap awal dari pembentukan karir. Perencanaan karir merupakan hal yang sangat penting untuk mencapai sukses. Penelitian ini bertujuan untuk mengetahui dan memperoleh bukti empiris tentang faktor-faktor yang memengaruhi pemilihan karir sebagai akuntan. Populasi penelitian ini yaitu mahasiswa akuntansi Fakultas Ekonomika dan Bisnis Universitas Majalengka. Metode yang digunakan untuk menentukan sampel yaitu sampel jenuh dengan jumlah sampel yang digunakan adalah 75 orang.
Penelitian ini menggunakan data kualitatif dan sumber data primer. Rancangan analisis data menggunakan analisis deskriptif dan verifikatif. Uji hipotesis dengan uji t dan uji F. Hasil penelitian ini menunjukkan bahwa penghargaan finansial dan personalitas berpengaruh terhadap pemilihan karir sebagai akuntan, baik secara parsial maupun simultan.
PENGARUH SISTEM AKUNTANSI PEMERINTAHAN, SISTEM PENGENDALIAN INTERN DAN GOOD GOVERNANCE TERHADAP KUALITAS LAPORAN KEUANGAN
Authors: Maulana M Robi 
Published: March 2022

This study aims to determine how the influence of the government accounting system on the quality of financial reports, the influence of the internal control system on the quality of financial reports, the effect of good governance on the quality of financial reports, and the effect of the government accounting system, internal control system and good governance simultaneously on the quality of financial reports. . The object of this research is the Regional Work Unit of Majalengka Regency.
This research uses descriptive analysis method and verification analysis method with data collection techniques using purposive sampling technique in which the sample used is determined based on criteria. Respondents in this study were the Head of Service, Secretary / General Affairs, and treasurer / financial management division at the Work Unit of Majalengka Regency, totaling 64 people. In this study, there are independent variables, namely the government accounting system, internal control system, and good governance, and the dependent variable is the quality of financial reports. The data analysis techniques used were correlation coefficient analysis, determination coefficient analysis, and hypothesis testing (t test and f test).
Based on the results of this study it can be concluded that the government accounting system affects the quality of financial reports, the internal control system affects the quality of financial reports, good governance affects the quality of financial reports, and the government accounting system, internal control system and good governance simultaneously affect the quality of reports. finance..
Evaluation of Sleep Quality with Use of Angiotensin Receptor Neprilysin Inhibitor in Patients with Reduced Ejection Fraction Heart Failure
Authors: Işık Ferhat , Okşul Metin , Aslan Burhan , Taştan Ercan 
Published: March 2022

Background and Aim: It is known that chronic heart failure reduces sleep quality by causing sleep problems. In recent years, it has been observed that sacubitril-valsartan, which is an angiotensin receptor neprilysin inhibitor, reduces mortality and hospitalization in patients with heart failure. The aim of our study is to examine whether sacubitril-valsartan affects sleep quality in patients with reduced ejection fraction heart failure apart from these benefits.
Material and Method: In our study, 44 patients with a history of heart failure with reduced ejection fraction applied to our cardiology outpatient clinic of Gazi Yaşargil Training and Research Hospital were included. Demographic, clinical, laboratory, electrocardiographic, and echocardiographic parameters of these patients were examined. Sacubitril-valsartan treatment was initiated in all patients. Dose titration was performed in patients who could tolerate the treatment. Pittsburgh sleep quality index questionnaire was performed in all patients before treatment and at the end of the second month.
Result: The median age of the study population was 61.5 (47.2 - 70.7, IQR) years and 30 (68.2 %) of them were male. There were 30 (72.7 %) ischemic heart failure patients and 14 (27.3 %) non-ischemic heart failure patients. There was a significant decrease in the number of patients with poor sleep quality after angiotensin receptor neprilysin inhibitor treatment compared to baseline [36 (81.8 %) vs 30 (68.2 %), p= 0.031]. In addition, there was a significant decrease in the total Pittsburgh sleep quality index score of patients compared to the baseline [9.0 (7.0 - 12.0) vs 7.0 (5.0 - 9.0), p < 0.001].
Conclusion: In our study, we observed that sacubitril-valsartan treatment improves sleep quality in patients with reduced ejection fraction heart failure.
Comparison of Clinical Profiles, Angiographic Features and Outcomes of Young and Elderly Patients with ST-Segment Elevation Myocardial Infarction
Authors: Murat Bektaş , Murat Selda 
Published: March 2022

Objective: It is to reveal the differences between clinical, angiographic, in-hospital and one-year follow-up results between young and elderly patients with acute ST-segment elevation myocardial infarction.
Material and Methods: This study was designed retrospectively in two centers. 2891 patients were screened; 260 of which were young. 260 elderly patients were randomly selected among the patients and the differences between both groups were evaluated.
Results: The median age of the young patients was 37 (34-39) years and the median age of the elderly patients was 65 (56-73) years, and male gender was dominant in both groups. Young patients were more likely to be admitted with Killip class 1, while older patients were more likely to be admitted with Killip class 2 (P=0.002). Single-vessel disease was more common in young patients (81.0% vs. 46.3%; P<0.001), while multi-vessel disease was more common in the elderly patients (19.0% vs. 53.7%; P<0.001). In one-year follow-up, all-cause hospitalization was lower in younger patients, but there was no significant difference in mortality between elderly and young patients.
Conclusion: Young patients presenting with ST-segment elevation myocardial infarction were more frequent smokers, obese and dyslipidemic and although in-hospital outcomes were better than the elderly, one-year mortality was similar to those of the elderly.
The Effect of Different Therapeutic Modalities on Demodex Densities and Clinical Symptoms of Patients with Demodicosis
Authors: Yalıcı Armağan Başak , Atakan Nilgün 
Published: March 2022

Background: Demodicosis represents cutaneous diseases caused by cutaneous overpopulation of Demodex mites. The aim of this study was to evaluate the effect of different treatment options on Demodex densities (Dds) and clinical symptoms of patients with demodicosis.
Methods: Patients with high Dds in two consecutive standardized skin surface biopsies (SSSB1>5 D/cm2 or SSSB2>10 D/cm²) and concomitant clinical symptoms were evaluated retrospectively. Measurements of treatment effectiveness included clinical improvement and normalization or reducing of Dds.
Results: A total of 21 patients included in the study. Five patients received topical permethrin and crotamiton whereas 16 patients received systemic metronidazole in combination with topical permethrin and/or crotamiton. The treatment was continued with topical ivermectin in 2 patients who had failure with other treatments. The median treatment duration was 3 months (IQR 1-4). Pre- and post-treatment median Dds decreased 30 to 14 D/cm2 on SSSB1 whereas 81 to 80 D/cm2 on SSSB2, respectively. There was no statistically significant decrease in Dds on SSSB1 and SSSB2 after the treatment (p=0.173 and p=0.134, respectively). Clinical improvement was recorded in a total of 14 patients (66.6%) of whom only 2 patients (9.5%) had normalization on Dds. Additionally, topical ivermectin provided a rapid clinical improvement and normalization on Dds in both 2 patients.
Conclusion: Irrespective of the treatment, more than two-thirds of the patients improved clinically without a significant change in Dds. This finding may suggest that the treatment response has been mostly associated with the anti-inflammatory properties of the agents. Topical ivermectin seems to be a more suitable treatment option for demodicosis with positive effects on both clinical findings and Dds.