bluuebunny/crossref_metadata_2025_split huggingface dataset:
Paraaortic and pelvic lymph node dissection in the combined treatment of recurrent ovarian cancer with isolated lymph node lesion: a literature review
Authors: Egenov O. A. , Tjulandina A. S. , Suleymanov E. A. , Stilidi I. S. 
Published: April 2022

The aim of the work is to analyze all available literature data on the role of secondary cytoreduction, its effectiveness and safety in the recurrence of ovarian cancer (ОС) with isolated lymph node (LN) lesion.The importance and place of secondary cytoreduction in the combined treatment of recurrent ОС is one of the most controversial topics. The lesion of the LN in recurrent Ос varies from 12 % to 37 %, but an isolated recurrence in the LN is a very rare occurrence, about 5 %. The most common localization in recurrent ОС with isolated LN lesion is the paraaortic LN.The results of this literature review suggest that isolated Ln lesion should be clearly distinguished from recurrence at other sites (such as peritoneal and parenchymal), since patients with isolated recurrence in the LN have a relatively indolent course of the disease. The frequency of complete cytoreduction according to the available data of retrospective studies reaches 100 %. Paraaortic and pelvic lymph node dissection without a macroscopically detectable residual tumor in combination with postoperative systemic chemotherapy leads to improved survival rates compared only with systemic drug treatment of patients with isolated LN lesion in recurrent ОС. median survival from the moment of relapse detection and overall survival varies from about 2.5 to 4 years and >5 years, respectively. Systemic paraaortic and pelvic lymph node dissection is preferable compared to selective lymphadenectomy, as it is accompanied by an increase in progression-free survival, although it doesn’t significantly prolong overall survival.
The Use of Information and Communication Technologies and Social Capital: the Nature of the Correlation
Authors: Mironova A.A. 
Published: April 2022

Objective. Critical analysis of existing research about the correlation between involvement in the use of information and communication technologies (ICT) and social capital; formulation of the author’s point of view on limitations of existing research about the correlation between ICT and social capital.Background. The development of ICT creates a new social reality and appearance of new social practices. Spreading of ICT and, in particular, the Internet, defines global changes in the technological context of communications. Social capital as one of the most important products of social interaction can be determined by the development of ICT, and at the same time social capital can influence the development of ICT. What is the nature of this relationship, how social capital will change in the context of ICT’s development, and how social capital affects the inclusion people in ICT’s using — these are the main questions that this study focuses on.Conclusions. Existing studies prove the correlation between social capital and developing of ICT. In doing so, both social capital influences the nature and intensity of ICT’s using, and ICT influence the creation and maintenance of social capital. This link can be analyzed not only on the individual, but also on the collective level. At the same time, the existing studies on the relationship between ICT and social capital have some limitations. Among the main limitations: imbalance in the levels of analysis (individual and collective levels) in studies on the relationship between ICT and social capital; lack of theoretical explanations of link mechanism between ICT and social capital; lack of studies that summarize the current knowledge about the relationship between ICT and social capital.
Online Social Media Communication: the Effect of Having Privacy Violation Experience on Online Behavior
Authors: Sinyavskaya Y.E. 
Published: April 2022

Objective. To analyze the effect of privacy violation experience on privacy-protective behaviorsBackground. In the era of rapid development of Internet technologies, privacy issues call for scientific reflection. Understanding the factors that regulate online user behavior might assist in elaborating the adequate privacy policy.Study design. Regression analysis provides a parametric evaluation of the effect of privacy experience on usage of privacy settings. Various matching technics were applied for preliminary balancing of the control (N=215) and treatment groups (N=160) by a set of key covariates.Participants. Users of the largest Russian online social network VKontakte from the Russian city Vologda. The sample size is 375 respondents (55% female) from 16 to 83 age (Mean=32,5; Med.=31; SD=12,9).Measurements. Both survey data on privacy experience and observed behavioral data on privacy settings from users’ online accounts were used. Additionally, the scale of P. Totterdell & D. Holman on propensity to make social connection and M. Rosenberg’s self-esteem scale were adopted in the studyResults. The experience of privacy violation does not lead to the cautious behavior online: the users tend to regulate only the access to the public posts on profile due to past bad experience. The privacy settings literacy turns significantly affect the usage of privacy settings.Conclusions. The findings support the “privacy paradox” hypothesis. As having specific online privacy management skills encourages more cautious behavior online, digital literacy interventions can improve the safety of social networking sites.
Impact of plasma glucose and duration of type 2 diabetes mellitus on SYNTAX Score II in patients suffering from non ST-elevation myocardial infarction
Authors: Biswas S. , Mukherjee A. , Chakraborty S. , Chaturvedi A. , Samanta B. , Khanra D. , Ray S. , Sharma R. K. 
Published: April 2022

Aim The objective was to assess the correlation of fasting plasma glucose (FPG), HbA1c, and the duration of type 2 diabetes mellitus (T2DM) with SYNTAX score (SS) II in patients with non-ST elevation myocardial infarction (NSTEMI).Material and methods FPG and HbA1C were measured in 398 patients presenting with NSTEMI at admission. SS II was calculated using an online calculator. Patients were stratified according to SS II (≤21.5, 21.5–30.6, and ≥30.6), defined as SS II low, mid, and high, respectively.Results 37.7 % of subjects were diabetic. Correlations of FPG (R=0.402, R2=0.162, p<0.001) and HbA1c (R=0.359, R2=0.129, p<0.001) with SS II were weak in the overall population. Duration of T2DM showed very strong correlation with SS II (R=0.827, R2=0.347). For the prediction of high SS II in the study population, FPG≥98.5 mg / dl demonstrated a sensitivity of 58 % and a specificity of 60 %, and HbA1c ≥6.05 demonstrated a sensitivity of 63 % and a specificity of 69 %. Duration of T2DM (adjusted odds ratio (OR): 1.182; 95 % confidence interval (CI): 1.185–2.773) and FPG (OR: 0.987; 95 % CI: 0.976–0.9959) were significantly associated with high SS II after controlling for other risk factors. Duration of T2DM (Beta=0.439) contributed strongly to variance of SS II, whereas HbA1c (Beta=0.063) contributed weakly.Conclusion Duration of T2DM is a very important risk factor for severity of coronary artery disease.
Association of dipping pattern of blood pressure and atherosclerotic burden of coronary arteries in hypertensive patients
Authors: Taşbulak O. , Aktemur T. , Şahin A. A. , Demir A. R. , Güler A. , Topel C. , Turkvatan A. , Pusuroglu H. , Erturk M. 
Published: April 2022

Aim The aim of this study was to determine the association between the dipping pattern of BP and coronary artery disease in hypertensive patients.Material and methods A total of 356 hypertensive patients were included in the study. The results of ambulatory BP monitoring, echocardiography, and coronary computerised tomographic angiography were evaluated retrospectively. The patients were divided into two groups on the basis of their ambulatory BP monitoring: 1) patients with the dipping pattern of BP; 2) patients with the non-dipping pattern (NDP).Results Among the 356 patients, 145 were male (40.7 %). The smoking status was higher in patients with NDP (p=0.023). The statin usage in patients with the dipping pattern was higher in patients with NDP (p=0.027). There were no significant differences in the echocardiographic findings. 58.6 % of the patients without plaque formation had the dipping pattern of BP (p<0.05), however 84.4 % of patients with >50 % plaque formation had the NDP of BP (p<0.001).Conclusion The NDP of BP might be related to the increased atherosclerotic process in coronary arteries, and pa­tients with NDP might have an increased atherosclerotic burden for coronary arteries when compared with patients with a dipping pattern.
Metabolic syndrome: Development of D.D.Pletnev’s and G.F.Lang’s ideas
Authors: Khalimov Yu. Sh. , Baranova E. I. , Belyaeva O. D. , Berkovich O. A. 
Published: April 2022

Metabolic syndrome is a problem of our time due to its high prevalence (from 20 to 50% in the adult population). The aim of the work was to outline the main stages in the study of the totality of hemodynamic and metabolic disorders that was later designated “metabolic syndrome”, in Russia. The article focuses on the development of the ideas of D.D.Pletnev and G.F.Lang from the beginning of the 20th century to the present at the Department of Faculty Therapy in Petrograd Medical Institute for Women, which was later named the First Leningrad Medical Institute and is now named Federal State Budgetary Educational Institution of Higher Education Academician I.P.Pavlov First St. Petersburg State Medical University under the Ministry of Healthcare of Russian Federation. The article discusses current trends in the study of the metabolic syndrome, including data from epidemiological studies on the prevalence of the metabolic syndrome and its individual components in Russia.Results. The paper presents the results of molecular genetic and instrumental methods for examining patients with abdominal obesity, metabolic syndrome, including those with complications such as atrial fibrillation, coronary heart disease, chronic heart failure with preserved left ventricular fraction. The review presents data on the molecular and other features of subcutaneous and visceral (epicardial) adipose tissue.Conclusion. The paper outlines priority areas for studying the metabolic syndrome in the future, which will be important for preventing the development and progression of this pathological condition.
Gut microbiome of healthy people and patients with hematological malignancies in Belarus
Authors: Akhremchuk Katsiaryna V. , Skapavets Katsiaryna Y. , Akhremchuk Artur E. , Kirsanava Natalia P. , Sidarenka Anastasiya V. , Valentovich Leonid N. 
Published: April 2022

ABSTRACT
Gut microbiota plays an important role in human health and the development of various diseases. We describe the intestinal microbiome of 31 healthy individuals and 29 patients who have hematological malignancies from Belarus. Bacteria that belong to Faecalibacterium, Blautia, Bacteroides, Ruminococcus, Bifidobacterium, Prevotella, Lactobacillus, and Alistipes genera were predominant in the gut of healthy people. Based on the dominant microbiota species, two enterotype-like clusters that are driven by Bacteroides and Blautia, respectively, were identified. A significant decrease in alpha diversity and alterations in the taxonomic composition of the intestinal microbiota were observed in patients with hematological malignancies compared to healthy people. The microbiome of these patients contained a high proportion of Bacteroides, Blautia, Faecalibacterium, Lactobacillus, Prevotella, Alistipes, Enterococcus, Escherichia-Shigella, Ruminococcus gnavus group, Streptococcus, and Roseburia. An increased relative abundance of Bacteroides vulgatus, Ruminococcus torques, Veillonella, Tuzzerella, Sellimonas, and a decreased number of Akkermansia, Coprococcus, Roseburia, Agathobacter, Lachnoclostridium, and Dorea were observed in individuals with hematological malignancies. Generally, the composition of the gut microbiome in patients was more variable than that of healthy individuals, and alterations in the abundance of certain microbial taxa were individually specific.
The Syriac Christianization of a Medical Greek Recipe: From Barbaros Hera to the “Apostles’ Ointment”
Authors: Asade Daniel , Druille Paola 
Published: April 2022

During the Late antiquity, several works by Galen (2nd–3th CE.) were translated into Syriac for the first time by Sergius of Rēšʽaynā (6th CE.), starting up the Hippocratic-Galenic medicine in Syriac Language. Based on these translations, there arouse novel versions of compound medicines in Syriac, such as the “Apostles’ Ointment” which is found in The Book of Medicines, possibly from Abassid period, edited and translated by E.A.W. Budge in 1913, which contains more ancient Syriac medical prescriptions. The textual pharmaceutical study regarding the therapeutic uses and qualitative composition of the ‘Apostles’ Ointment’, and its comparison with a kind of plaster (barbaros) which appears in various Late antiquity Greek recipes (Galen, Oribasius, Aetius of Amida, and Paul of Aegina), reveal the micro-transformations suffered to a new and final Syriac Christian version which we here introduce.
Constantine X Doukas (1059–1067) versus Uzes – about the Nomads on Boats on the Danube in 1064
Authors: Böhm Marcin 
Published: April 2022

The reign of the Doukas dynasty in 1059–1078 was a time when new threats to the Byzantine Empire emerge in Europe and Asia. One of them was the increased activity of Turkmen who were penetrating the lands belonging to the Byzantines. A manifestation of these threats was visible during the rule of Constantine X Doukas (1059–1067) in 1064. We have there an invasion of the tribe of Uzes, who crossed the Danube. They ventured so far, as the vicinity of Thessalonica and the province of Hellas, plundering everything in their path. Their actions surprised the defense of the Byzantines. This attack on the empire was related to their crossing of the Danube, about which Michael Attaliates and Skylitzes Continuatus provides us with interesting information. The main aim of this paper therefore will be related to issues linked to the types of vessels used by Uzes to cross this river, as well as an attempt to assess their boatbuilding skills.
Personal health and nutrition information-seeking attitudes and behaviours of first year Canadian and United States veterinary students
Authors: Nielson Shelby , Kamleh May , Conlon Peter , McWhirter Jennifer , Stone Elizabeth , Khosa Deep 
Published: April 2022

Objective: To identify the primary sources of information first year Canadian and US veterinary students relied on for their personal health and nutrition information, and to explore their attitudes towards, and perceptions of, health information resources.
Background: Though the animal health information-seeking behaviours (HISB) of veterinary students have been explored, research regarding personal HISB of this professional student population is limited.
Evidentiary value: Participants were first year veterinary students (n=322) at the five Canadian veterinary schools and five randomly selected US veterinary schools. An online questionnaire was used to gather students’ demographic information, sources of health and nutrition information, and information-seeking attitudes and perceptions. This study may impact practice at the institutional level for veterinary educators.
Methods: STATA 15.1© was used for quantitative analysis; involving multivariate logistic regression models, univariate analyses, and measures of frequency.
Results: Results indicated high reliance on the Internet for personal health 213/322 (66%) and nutrition 196/322 (61%) information. While respondents revealed high trust levels in dietary recommendations from family doctors, 132/322 (41%) of students revealed their doctor did not provide any information on healthy diets. Students who reported the use of peer-reviewed journal articles for personal nutrition information were at greater odds of having confidence in knowing where to find nutrition information (Odds Ratio [OR] = 6.61, p<0.001).
Conclusion: Participating students reported a high reliance on the Internet search engine Google, and a general lack of guidance from medical professionals regarding general health needs.
Application: Veterinary schools should consider this information to enhance student information literacy skills, particularly to facilitate personal HISB, and consequently help in management of personal health throughout the growing demands of the programme.
Czy radio cyfrowe jest przyszłością radiofonii w Polsce?
Authors: Ostrowska Marta 
Published: April 2022

Mimo że środki masowego przekazu na całym świecie poddane zostały procesowi cyfryzacji, radio w Polsce wciąż pozostaje analogowe. Media w standardzie analogowym, na przykład telewizja, uznane zostały już dawno za przestarzałe. Jednak temat cyfryzacji radiofonii wciąż stanowi przedmiot ożywionych dyskusji w środowisku medialnym, a wiedza na jego temat wśród społeczeństwa jest ograniczona.
Wprowadzanie standardu cyfrowego na rynek jako rozwiązanie docelowe wiąże się z problemami, z którymi należy się zmierzyć niezależnie od systemu i struktury rynkowej. Trudności, takie jak koszty równoległej emisji analogowej i cyfrowej, niewystarczająca wiedza na temat radia cyfrowego czy niechęć wykorzystania standardu przez dużych nadawców komercyjnych występują również w innych krajach europejskich. Na podstawie obserwacji chronologii wprowadzanych tamże zmian można określić działania, jakie należałoby podjąć w Polsce, by optymalnie przeprowadzić proces implementacji technologii cyfrowej do emisji radiowej.
A Case Report of Tinea Capitis in Children: Utility of Trichoscopy
Authors: Harningtyas Citra Dwi , Ervianti Evy , Astari Linda , Anggraeni Sylvia , Widia Yuri 
Published: April 2022

Background: Tinea capitis (TC) is the most prevalent pediatric superficial dermatophyte infection. Scalp dermoscopy or “trichoscopy” represents a valuable, noninvasive technique for the evaluation of patients with hair loss due to TC. Purpose: To characterize trichoscopic findings in children with clinical findings suggestive of TC. Case: A 13-year-old boy was presented with a scaled plaque on his scalp that had appeared 1 month earlier. A physical examination revealed a scaly, nonerythematous, rounded lesion in the parietal area of the head. Wood’s lamp yielded a blue fluorescence. Microscopic morphology from fungal culture found the typical spindle-shaped macroconidia of Microsporum canis. Trichoscopy showed mainly comma hair, corkscrew hair, morse code hair, bent hair, and zig zag hair. The patient was started on oral griseofulvin 20 mg/kg/day and antifungal shampoo for 8 weeks. The patient was cured after two months of treatment and trichoscopy returned to normal. Discussion: Fungal culture remains the gold standard in TC diagnosis, but it needs time. Trichoscopy can be an additional tool to help evaluate the diagnosis, aetiology, and follow up of this disorder. The presence of characteristic trichoscopic features (comma hairs, corkscrew hairs, Morse code-like hairs, zigzag hairs, bent hairs, block hairs, and i-hairs) is predictive of TC. The present analysis confirmed that trichoscopy is a useful method in differentiating between Microsporum and Trichophyton TC, which is important from the perspective of a different therapeutic approach. Conclusion: Trichoscopy is not only of value in the diagnosis of TC but also for the etiologic agent and follow-up after treatment in this case.
Measurement of Trans-Epithelial Electrical Resistance (TEER) with EndOhm Cup and EVOM2_Version 2.0
Authors: Mallek Nicholas M. , Simmons Alysha E. , McCullough Shaun D. 
Published: April 2022

Abstract
Trans-epithelial Electrical Resistance (TEER) can be used as a measure of cell monolayer confluence, health, and integrity. An EndOhm chamber connected to an Epithelial Voltohmmeter (EVOM) may be used to take TEER measurements that are more reproducible than the chopstick electrode. This method details how to take TEER readings using an EndOhm chamber and EVOM2 manufactured by World Precision Instruments. Read the manufacturer’s manual carefully as the conditions described here were determined to meet the manufacturer’s specifications. Disclaimer: The contents of this article have been reviewed by the US Environmental Protection Agency and approved for publication and do not necessarily represent Agency policy. Mention of trade names or commercial products does not constitute endorsement or recommendations for use.NOTE: There is a consolidated PDF version of this protocol in the supplementary files section below.
Comparison of Ticagrelor and Clopidogrel on Inflammatory Biomarkers in Actue Myocardial Infarction Patients ----- A multicenter randomized, open-label and parallel- treatment prospective clinical study
Authors: li zhenhua , Zhang Tao , Li Yueyan , Hao Rui , Li Qian , Su Guohai 
Published: April 2022

Abstract
OBJECTIVE
The aim of this study was to assess the different impacts on inflammatory biomarkers of ticagrelor or clopidogrel in patients with ST-segment elevation myocardial infarction (STEMI) undergoing emergency percutaneous coronary intervention (PCI).
METHODS
This was a multicenter, randomized, open-label and parallel- treatment prospective study. Patients were randomized to receive a loading dose of ticagrelor 180 mg as the treatment group (N = 143) or clopidogrel 600 mg as the control group (N = 184). After PCI, the treatment group was treated with ticagrelor 90 mg twice daily while the control group was treated with clopidogrel 75 mg once daily. The levels of inflammation were tested by sCD40 ligand (CD40L), high sensitivity C-reactive protein (hsCRP) and P-selectin in different time points.
RESULTS
There were 327 patients participated in this study and no difference in baseline characteristics between groups. No difference was found between groups in baseline levels of inflammation with all assays, and no difference in assays of hsCRP and P-selection in all the time points between groups, but sCD40L decreased significantly in ticagrelor group than clopidegrel group (-2492 ± 7407.3 VS 992.21 ± 10478, P = 0.0095) in 1week after PCI.
CONCLUSIONS
In STEMI patients undergoing PCI who are receiving anti-platelet therapy, ticagrelor is associated with more potent inflammation inhibition of sCD40L compared with clopidogrel in 1week after PCI. It may open a new path for anti-platelet therapy and large studies are needed to support this finding.
A new approach of using area under the curve of absorption profile to optimize the active layers of photovoltaic devices
Authors: Amin Peshawa O. , Muhammadsharif Fahmi F. , Saeed Salah Raza , Ketuly Kamal Aziz 
Published: April 2022

Abstract
Optimization of photovoltaic (PV) active layers is usually carried out in terms of the energy bandgap (Eg) variation of the bulk heterojunction (BHJ) layers. However, the non-monotonic change in the Eg does not guarantee the achievement of a maximum absorption capability at the optimum condition despite the broadened absorption spectrum. Hence, alternative strategies need to be researched in order to assign the best possible condition at which the active layer can convert the highest possible number of exposed photons to free electrons when it is employed in PV devices. Therefore, in this work, we propose a new approach which can be effectively used to optimize the BHJ active layers in terms of photon to electron conversion, considering the absorption profile of the system. Herein, area under the curve (AUC) of the absorption profile is utilized to optimize the active layers of photovoltaic devices. To formulate the proposed technique, a ternary system based on P(TRI-co-TER):Beetroot dye:PINDOLE was investigated and analyzed. Results showed that a linear correlation was produced between the AUC and photocurrent density (Jph), which can be ultimately used to optimize the active layers of PV devices.