bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relación entre desnutrición crónica en menores de cinco años y la edad, el nivel de escolaridad y el número de hijos nacidos vivos de sus madres, en tres comunidades que conforman los Sitios Centinela de la Seguridad Alimentaria y Nutricional (SICESAN) de la Mancomunidad Trinacional Fronteriza del Río Lempa (MTFRL) en el año 2014
Authors: Lezama Mendoza Gioconda , Sibrián Ricardo 
Published: April 2022

Se determinó la relación del estado nutricional de niños y niñas menores de cinco años y la edad, escolaridad y número de embarazos de sus madres en las comunidades de Las Toreras, Dolores Merendón en Honduras; San Ramón Centro, Citalá en El Salvador y Las Palmas, Olopa en Guatemala que conforman los sitios centinela de la seguridad alimentaria y nutricional (SICESAN) de la Mancomunidad Trinacional Fronteriza del Rio Lempa (MTFRL), en el año 2014.Bajo un diseño de tipo descriptivo y transversal, se le aplicó un formulario socio-demoFigura y se realizaron mediciones antropométricas a los niños, se determinaron los factores de riesgos para la desnutrición crónica (retardo de crecimiento talla/edad o retardo de altura para su edad) sustentando que la misma es multicausal, fue significativo vincular la edad de la madre y su nivel de escolaridad como elementos que pueden contribuir de forma importante en el estado nutricional de sus hijos. Los hijos de madres menores de edad, especialmente las menores de veinte años con nivel de escolaridad entre 1-4 grado de primaria presentaron mayor prevalencia de retardo de crecimiento (ZTE de -2.42) en comparación con los hijos de madres con edad igual o mayor de treinta años con el mismo nivel de escolaridad, cuya prevalencia fue menor (ZTE -2.01). La condición de los menores mejoro significativamente a razón de mayor edad de las madres y mayor número de grados escolares aprobados. Los hijos de madres menores de 20 años edad, con nivel de escolaridad mayo a cuarto grado
Research on the Development Course and Countermeasures of Chinese Financial Derivatives Market
Authors: Fan Zesen , Liu Kaiyue 
Published: April 2022

With the development of times, the trading volume of financial derivatives continuously extend, and its growth rate has exceeded that of traditional financial products. China's financial derivatives market is a crucial part of the financial system, showing a trend of optimized development, and international influence significantly improved. However, compared with the mature financial market abroad, there are still many problems in China's financial derivatives market. The paper analyzes the development course and problems of China's financial derivatives market, and puts forward the countermeasures to effectively promote the development of China's financial derivatives market, in order to enhance the competitiveness of China's financial derivatives market.
Zelfbewust en op impact gericht beleidsonderzoek is onmisbaar voor de legitimiteit van de overheid in een nieuw sociaal contract
Authors: Putters Kim 
Published: April 2022

Zelfbewust en op impact gericht beleidsonderzoek is onmisbaar voor de legitimiteit van de overheid in een nieuw sociaal contract
Beleidsonderzoekers kunnen niet alle patronen doorbreken die ons sociaal contract op de proef stellen, maar ze kunnen wel verschil maken door spiegels voor te houden en handelingsperspectieven te bieden. Te vaak wordt meer bewijswaarde gehecht aan rationeel-analytisch of positivistisch onderzoek, zoals doelmatigheidsonderzoek, en minder aan kwalitatief onderzoek, dat meerdere realiteiten benadrukt. Beleidsonderzoekers kunnen laten zien hoe dit elkaar aanvult en van betekenis is voor effectief en legitiem beleid. In dit essay laat de auteur zien wat een sterk sociaal contract vraagt van beleidsmakers en onderzoekers.
PENGARUH ROH MENYALA-NYALA DALAM MELAYANI TUHAN MENURUT ROMA 12:11 TERHADAP SEMANGAT PELAYANAN MAHASISWA SEKOLAH TINGGI TEOLOGI DUTA PANISA JEMBER
Authors: Mendrofa Agus Kristiani 
Published: April 2022

The development of the era towards the millennial era has dragged people tohave an all-istan lifestyle and attitudes of individualism, pragmatism, and indifference to become stronger in the midst of life together. This attitude has crawled and influenced the lifestyle of servants of God and church activists so that it has an impact on what is the main task of servants of God as social beings and servants of God, namely to care for and serve one another. To maintain the spirit of service to others, it is necessary to have a burning spirit in the life of the servant of God. Therefore, this research is an analysis of how much influence a burning spirit according to Romans 12:11 has on the spirit of service. This study uses quantitative methods using descriptive experimental design in order to determine the effect of a burning spirit on the spirit of service. Based on the data analysis, the results of the calculation of the data with the help of SPSS 16.0 indicate that the burning spirit variable (X) has a significance value of 0.048 <0.05, it can be concluded that the burning spirit variable (X) has a significant effect on the variable. spirit of service (Y).
Integrated bioinformatics analysis for the identification of hub genes and signaling pathways related to circANRIL
Authors: Qin Qiuyan , Zheng Pengfei , Tu Ronghui , Huang Jiegang , Cao Xiaoli 
Published: April 2022

Background
Antisense noncoding RNA in the INK4 locus (ANRIL) is located on human chromosome 9p21, and modulation of ANRIL expression mediates susceptibility to some important human disease, including atherosclerosis (AS) and tumors, by affecting the cell cycle circANRIL and linear ANRIL are isoforms of ANRIL. However, it remains unclear whether these isoforms have distinct functions. In our research, we constructed a circANRIL overexpression plasmid, transfected it into HEK-293T cell line, and explored potential core genes and signaling pathways related to the important differential mechanisms between the circANRIL-overexpressing cell line and control cells through bioinformatics analysis.

Methods
Stable circANRIL-overexpressing (circANRIL-OE) HEK-293T cells and control cells were generated by infection with the circANRIL-OE lentiviral vector or a negative control vector, and successful transfection was confirmed by conventional flurescence microscopy and quantitative real-time PCR (qRT-PCR). Next, differentially expressed genes (DEGs) between circANRIL-OE cells and control cells were detected. Subsequently, Gene Ontology (GO) biological process (BP) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed to explore the principal functions of the significant DEGs. A protein–protein interaction (PPI) network and competing endogenous RNA (ceRNA) network were constructed in Cytoscape to determine circularRNA (circRNA)- microRNA(miRNA)-messenger RNA (mRNA) interactions and hub genes, and qRT-PCR was used to verify changes in the expression of these identified target genes.

Results
The successful construction of circANRIL-OE cells was confirmed by plasmid sequencing, visualization with fluorescence microscopy and qRT-PCR. A total of 1745 DEGs between the circANRIL-OE group and control were identified, GO BP analysis showed that these genes were mostly related to RNA biosynthesis and processing, regulation of transcription and signal transduction. The KEGG pathway analysis showed that the up regulated DEGs were mainly enriched in the MAPK signaling pathway. Five associated target genes were identified in the ceRNA network and biological function analyses. The mRNA levels of these five genes and ANRIL were detected by qRT-PCR, but only COL5A2 and WDR3 showed significantly different expression in circANRIL-OE cells.
Role of Black Salt to Reduce in Hypertension, Reality and Evidence Based Studies
Authors: Sen Naresh , Tanwar Sonal 
Published: April 2022

Salt in diet is very important to make our life healthy and energetic. Quantity and quality of salt with appropriate ratio or balance in electrolytes which are responsible for volume of body, blood velocity, for functions of receptors and enzymes, to prevent inflammation, proliferation and to make balance in muscles contraction and nerve conduction through to avoid high stimulation of sympathetic nervous system. Hence, scanning and focus with monitoring and supply of healthy salt in limits may prevent volume overload, renal dysfunction & left ventricular hypertrophy, to prevent cardiac functions, to avoid the weaken gut immunity and also to prevent cerebral oedema, cerebral aneurysm and hypertension cause stroke. Control of salt with intake of low quantity and high quality with more frequency of intervals during 24 hours in required amount of salt in balanced electrolytes may help to avoid high salt sensitivity. Balanced salt intake is also important to avoid volume expansion and obesity with reduction of insulin resistance leads to prevent hypertension and diabetes which are leading risk factors for cardio-renal syndrome, cardiovascular morbidity and mortality. Our data suggested a 2.5-fold higher risk for high blood pressure in sea or white salt users versus black salt or Himalayan rock salt which showed more potassium and magnesium with low sodium ions as compared to sea salt.
The Influence of Modern Lifestyle on the Health of Medical Students in a Medical School in Dominica
Authors: Victoire Schilo La , Ukwandu Stephanie , Ejuone Oghenetega , Monday Esther O. 
Published: April 2022

Background: A healthy lifestyle is a way of living that reduces the risk of being severely ill. In 1967, the World Health Organization (WHO) defined health as “of complete physical, mental and social well-being and not merely the absence of disease or infirmity ». An unhealthy diet and lack of physical activity are in the lead for global health risks.
Aim: This study explored the impact modern lifestyle has on the health of medical students
Methods: Our study included a literature review, and a questionnaire consisting of 24 questions which were answered by 76 participants which targeted; diet, exercise regimen, sleep cycle, alcohol, substance use, and technology use.
Results: From the responses, 63.1% of respondents practice a sedentary lifestyle, 68.4% skip breakfast and 35.5% have an unhealthy diet.
Conclusion: There is a need for individuals to pay attention to their daily practices as modern lifestyle can have a negative impact on quality of life.
Post-injection Complications. Nicolau Syndrome as a Consequence of Local Irritant Effects of Drugs, Including Antiseptics, Local Anesthetics, NSAIDs, Steroids and Anticoagulants
Authors: Urakov Aleksandr , Urakova Natalya , Fisher Evgeny , Bashirov Ilnur , Nurlanova Sabina , Klimovich Anastasia , Fakhretdinova Albina , Bakirov Anvar , Balametova Regina , Samorodov Aleksandr 
Published: April 2022

It has been shown that some drugs considered to be of good quality today can cause an iatrogenic disease known as Nicolau syndrome. Nicolau syndrome is a rare cutaneous drug reaction occurring after injection many drugs. This disease has been found to be caused by the very strong local irritant activity of drug solutions. It turned out that the standard for assessing the quality of drug solutions does not include assessment of their osmotic activity and the strength of their local irritating effect on various tissues during injection. At the same time, drug solutions produced by different pharmaceutical companies may contain, in addition to the main ingredients, other ingredients (hydrochloric acid, sodium hydroxide, propylene glycol, etc.). Very often the additional ingredients increase the osmotic activity of the drug solution, which is not controlled today, so it remains unknown. This is why drug solutions produced by some pharmaceutical companies can have hypertonic activity, which can sometimes by ignorance reach values that are incompatible with the vital activity of human body tissue cells. Therefore, injections of such drug solutions can have a very strong dehydrating effect on the tissue cells at the injection sites, have a local irritating and cauterizing effect. It has been shown that even steroid solutions in some manufacturers may have excessive hypertonic and acidic activity, which gives them a local irritating effect. This is why in some cases the injection of a steroid solution does not eliminate, but rather increases local inflammation and causes necrosis. Therefore, to exclude postinjection necroses and abscesses, it is proposed to include an assessment of the osmotic activity and local irritant effect of drug solutions in the drug quality control standard and to prohibit the injection of drug solutions with excessive hypertonic activity.
Filling Octahedral Interstices by Building Geometrical Defects to Construct Active Sites for Boosting the Oxygen Evolution Reaction on NiFe2O4
Authors: Peng Yang , Huang Churong , Huang Jingle , Feng Min , Qiu Xinzhuo , Yue Xin , Huang Shaoming 
Published: April 2022

AbstractOwing to the faster kinetics and outstanding catalytic performance, spinel oxides are regarded as a potential non‐precious metal electrocatalyst for oxygen evolution reaction (OER). Regulation of the geometrical structures of the spinel oxides is one of the most effective approaches for enhancing their OER performance. However, more wide and deep investigations remain because of the structural complexity of spinel oxides, for example, how to fill the unoccupied octahedral interstices to construct a large number of active sites for boosting the OER. Herein, iron foam (IF) supported NiFe2O4 nanocubes with high occupancy at octahedral sites (HOoct‐NFO NC/IF) are synthesized by hydrothermal method followed by anchoring and annealing. Detailed structural characterizations indicate that the foreign Fe cations can be filled into the octahedral interstices along the geometrical defects channel of transition metal cations coordinated with six oxygen anions (TMO6) by etching TMO6 units with an anchoring agent. As a result of the increasing of TMO5 sites with better activity and tuning of the electronic structures, the as‐fabricated HOoct‐NFO NC/IF electrocatalysts exhibit excellent performance for OER with overpotentials of 260 and 310 mV to reach 10 and 400 mA cm−2, respectively. Meanwhile, the catalysts show faster kinetics and superior stability.
Deep Neural Network with Data Cropping Algorithm for Absorptive Frequency‐Selective Transmission Metasurface
Authors: Wang Jiayi , Xi Rui , Cai Tong , Lu Huan , Zhu Rongrong , Zheng Bin , Chen Hongsheng 
Published: April 2022

AbstractDeep neural networks (DNNs) are widely used in designing a metasurface; however, data acquisition from simulations is expensive in terms of time and effort. Inspired by image cropping, a data cropping algorithm is proposed that can significantly reduce the simulation time required in the DNN pre‐training process. The algorithm crops the simulated data and adds random data to augment the amount of the dataset. By applying the proposed target‐driven DNN, an absorptive frequency‐selective transmission (AFST) metasurface structure with a low profile and a broad transmission band is designed. A transmission band from 7.5 to 14 GHz and an absorption rate as large as 0.75 beyond the transmission band are observed. The proposed method provides an efficient strategy to design metasurfaces and a fast solution to the electromagnetic inverse design problem.
Growth of N‐Heterocyclic Carbene Assemblies on Cu(100) and Cu(111): From Single Molecules to Magic‐Number Islands
Authors: Navarro Juan J. , Das Mowpriya , Tosoni Sergio , Landwehr Felix , Koy Maximilian , Heyde Markus , Pacchioni Gianfranco , Glorius Frank , Roldan Cuenya Beatriz 
Published: April 2022

AbstractN‐Heterocyclic carbenes (NHCs) have superior properties as building blocks of self‐assembled monolayers (SAMs). Understanding the influence of the substrate in the molecular arrangement is a fundamental step before employing these ligands in technological applications. Herein, we study the molecular arrangement of a model NHC on Cu(100) and Cu(111). While mostly disordered phases appear on Cu(100), on Cu(111) well‐defined structures are formed, evolving from magic‐number islands to molecular ribbons with coverage. This work presents the first example of magic‐number islands formed by NHC assemblies on flat surfaces. Diffusion and commensurability are key factors explaining the observed arrangements. These results shed light on the molecule‐substrate interaction and open the possibility of tuning nanopatterned structures based on NHC assemblies.
Identification of 9H‐purin‐6‐amine derivatives as novel aldose reductase inhibitors for the treatment of diabetic complications
Authors: Zhu Junkai , Qi Gang , Kuang Yan , Zhao Yating , Sun Xinjie , Zhu Changjin , Hao Xin , Han Zhongfei 
Published: April 2022

AbstractA series of 9H‐purin‐6‐amine derivatives as aldose reductase (ALR) inhibitors were designed and synthesized. Most of these derivatives, having a C6‐substituted benzylamine side chain and N9 carboxylic acid on the core structure, were found to be potent and selective ALR inhibitors, with submicromolar IC50 values against ALR2. Particularly, compound 4e was the most active with an IC50 value of 0.038 μM, and it was also proved to be endowed with excellent inhibitory selectivity. The structure–activity relationship and molecular docking studies highlighted the importance of the carboxylic acid head group along with different halogen substituents on the C6 benzylamine side chain of the 9H‐purin‐6‐amine scaffold for the construction of strong and selective ALR inhibitors.
Objective measurement of vocalizations in the assessment of autism spectrum disorder symptoms in preschool age children
Authors: Moffitt Jacquelyn M. , Ahn Yeojin Amy , Custode Stephanie , Tao Yudong , Mathew Emilin , Parlade Meaghan , Hale Melissa , Durocher Jennifer , Alessandri Michael , Perry Lynn K. , Messinger Daniel S. 
Published: April 2022

AbstractAssessment of autism spectrum disorder (ASD) relies on expert clinician observation and judgment, but objective measurement tools have the potential to provide additional information on ASD symptom severity. Diagnostic evaluations for ASD typically include the autism diagnostic observation schedule (ADOS‐2), a semi‐structured assessment composed of a series of social presses. The current study examined associations between concurrent objective features of child vocalizations during the ADOS‐2 and examiner‐rated autism symptom severity. The sample included 66 children (49 male; M = 40 months, SD = 10.58) evaluated in a university‐based clinic, 61 of whom received an ASD diagnosis. Research reliable administration of the ADOS‐2 provided social affect (SA) and restricted and repetitive behavior (RRB) calibrated severity scores (CSS). Audio was recorded from examiner‐worn eyeglasses during the ADOS‐2 and child and adult speech were differentiated with LENA SP Hub. PRAAT was used to ascertain acoustic features of the audio signal, specifically the mean fundamental vocal frequency (F0) of LENA‐identified child speech‐like vocalizations (those with phonemic content), child cry vocalizations, and adult speech. Sphinx‐4 was employed to estimate child and adult phonological features indexed by the average consonant and vowel count per vocalization. More than a quarter of the variance in ADOS‐2 RRB CSS was predicted by the combination of child phoneme count per vocalization and child vocalization F0. Findings indicate that both acoustic and phonological features of child vocalizations are associated with expert clinician ratings of autism symptom severity.Lay SummaryDetermination of the severity of autism spectrum disorder is based in part on expert (but subjective) clinician observations during the ADOS‐2. Two characteristics of child vocalizations—a smaller number of speech‐like sounds per vocalization and higher pitched vocalizations (including cries)—were associated with greater autism symptom severity. The results suggest that objectively ascertained characteristics of children's vocalizations capture variance in children's restricted and repetitive behaviors that are reflected in clinician severity indices.
Academic employees' green behaviour as praxis for bolstering environmental sustainable development: A linear moderated mediation evaluation
Authors: Fawehinmi Olawole , Yusliza Mohd Yusoff , Ogbeibu Samuel , Tanveer M. Imran , Chiappetta Jabbour Charbel Jose 
Published: April 2022

AbstractThere have been calls for organisational employees across developed and emerging economies to be more responsible towards the environment because of the heightened level of devastation in the ecosystem due to human actions. This study examines the influence of environmental concern on employee green behaviour (EGB) through the mediation of attitude, perceived behavioural control (PBC), and environmental knowledge. SmartPLS 3 software was used to analyse the relationships from 425 valid responses. The findings of our study show that environmental concern, attitude, and PBC positively predict the EGB of academics. Attitude and PBC act as complimentary mediators of the relationship between environmental concern and EGB. Equally, a linear moderated mediation analysis shows that environmental concern amplifies the link between PBC and EGB. Furthermore, an importance‐performance map analysis (IPMA) provides evidence that suggests that though employees' attitude is a less important predictor of EGB when compared with environmental concern, their respective degree of performance is equal to each other. Furthermore, this study offers substantive insights into the multiple roles of environmental concern in influencing employee green behaviour among academics in higher education institutions (HEIs). Policy implications and future research directions for environmental sustainability are discussed.
Cerebral astroblastoma radiologically mimicking pilocytic astrocytoma: A case report
Authors: Joshi Padam Raj , Pandey Sagar Babu , Manandhar Usha , GC Saroj , Sedain Gopal 
Published: April 2022

AbstractAstroblastoma is a rare central nervous system tumor. We reported a case of a 24‐year‐old Nepalese woman with radiological features mimicking pilocytic astrocytoma which came out to be low‐grade astroblastoma in histopathological and immunohistochemistry examination after total excision of the tumor.
Effect of Transmembrane Pressure on Antifouling Properties of PVC/Clinoptilolite Ultrafiltration Nanocomposite Membranes
Authors: Etemadi Habib , Kazemi Rozita , Ghasemian Naser , Shokri Elham 
Published: April 2022

AbstractNovel polyvinyl chloride (PVC)/clinoptilolite nanocomposite membranes for water treatment were fabricated by non‐solvent‐induced phase separation and characterized with respect to their hydrophilicity, porosity, surface roughness, thermal stability, and surface and cross‐sectional morphology. All prepared membranes were evaluated in a submerged system for the removal of humic acid (HA) under various vacuum transmembrane pressure (TMP) conditions. The hydrophilicity, porosity, and thermal stability of the membranes were increased by the addition of 0.5 wt % clinoptilolite nanoparticles. A larger macrovoid appeared when clinoptilolite nanoparticles were added to the PVC membrane. Higher TMP leads to serious fouling and the formation of a thicker foulant layer on the membrane surface as well as less removal of HA.