bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effects Of Supply Chain Management On Competitive Advantage: The Case Of Manufacturing Companies In Ethiopia
Authors: Isho Mohammed Yassin 
Published: July 2022

Abstract
Now a days firms are not only competing as autonomous units instead they entered in to an era of competing among different supply chains, leading them to work as a team in the form of network of business relationship. As competition becomes stiff, firms must be more involved in how their suppliers and customers conduct their businesses. To succeed in today’s challenging business environment, firms must be able to effectively integrate the internal function within a company and effectively link them with the external operations of supply chain members. Due attention should be given by firms to supply chain management practices as it has significant influence in enhancing SCM functions and ultimately performances. Accordingly, the objective of this study is to examine the practices and effect of supply-chain management on firms’ competitive advantage; and to look at the effect of inventory management on firms’ performance. Moreover, the study attempted to identify major challenges of supply-chain management in selected manufacturing firms in Ethiopia. To attain the objectives quantitative approach was employed. Moreover, a descriptive inquiry along with causal research design was used. Primary data were obtained from survey questionnaires. Large manufacturing firms; 2 textiles and 2 sugars were selected as samples using purposive sampling technique. In addition, 4 officials from each of the eight departments’ viz., General Managers, Purchasing managers, Technical managers, Operation managers, Quality managers, Transport managers, Sales and IT managers were selected from the four firms included in the study. Hence, a total of 128 respondents from each of the three studies were judgmentally selected. The collected data were analyzed using SPSS 20.0 version using descriptive statistics, Correlation analysis and multiple regressions analysis. Accordingly, based on the regression result it is revealed that the supply chain dimensions included in the study viz., customer relationship management, customer service management, level of information sharing, demand management process, environmental issues, and supplier relationship management were positively and significantly affect firms competitive advantage. Finally, it is suggested that manufacturing firms should create close relationship with customers to differentiate their products from competitors. Moreover, manufacturing firms are recommended to apply information technology like electronic data interchange within and among the supply chain umbrellas as a whole.
Women’s Value In A Social Capital Context: A Net Present Social Value Analysis
Authors: Fadare Stephen Ayoade 
Published: July 2022

Social capital is formed from individual abilities through the social investment that contributes to value creation where individuals feel a sense of membership and commitment through their social interactions and relationships. This study aims to explore the application of social capital to women's organizations. It further explores the net social value of women's organizations and the women members to determine social capital's role as a means for value creation. At these ends, the mixed method was employed by combining qualitative and quantitative data gathering approaches. The study used key informant interviews among 11 women's organizations in Baguio City and Benguet, where a total of 284 women members were interviewed. The result of the talks was subjected to semantic analysis and net present social value analysis. The results reveal that women's organizations reflect the dimensions of social capital and bring a significant contribution to members' lives. The findings imply that women members are duly recognized in their organizations, and each member expects to receive a positive value of the social benefit. Hence, women's organizations are the embodiment of social capital that contributes to women's value creation and empowers their members to maximize their capacities.
Amphorae of Roman Time from Excavations at Settlement on Berezan Island (in Collection of Odesa Archaeological Museum of NAS of Ukraine)
Authors: Masyuta Denis 
Published: July 2022

The author presents the finds of amphorae of the Roman time, which were found on the island of Berezan. Materials that are introduced into scientific circulation are stored in the depositaries of the Odesa Archaeological Museum of the National Academy of Sciences of Ukraine. They are mainly represented by fragments of amphorae, which were found as a result of the work of archaeological expeditions headed by M.F. Boltenko (1927, 1928, 1930, 1931, 1946) and V.V. Lapin (1960, 1961) at Berezan settlement. Some of the finds also came from the island of Berezan, but the year and place of their finding are unknown.
A comprehensive study of amphorae fragments gives the opportunity to reconstruct the trade relations of the settlement, which was located on the island of Berezan in the first centuries AD. Products in transport amphorae appeared on the island in the early Roman time. Thus, in amphorae of type Vnukov S І, dating no later than the first third of the 2nd century AD, Heraclean wine, made according to Coan recipe, was imported. Subsequently, the products of Heraclea Pontica sporadically came in amphorae of variant Vnukov S IVC.
The peak of trade activity of the settlement was attained in the end of the 2nd – the middle of the 3rd century AD. The range of products imported in transport wares during that period was rather wide. Heraclean wine was imported in large quantities (in amphorae of variant Vnukov S IVD) as opposed to much lesser quantities of the Aegean wine (in vessels of type Kapitän II) and Cilicia wine (in amphora of type Agora G 199). Probably, there was wine in amphora of type Zeest 72 or Zeest 73, which came to the island from an unidentified production site.
Bosporus ‘salsamentum’, which had been very popular among the inhabitants of Berezan settlement since the end of the 2nd century AD was transported in amphorae of type Zeest 75 (variants A, C, D), and from the beginning of the 3rd century AD, also in a rather rare container of type Krapivina 27 (variants ‘a’ and ‘b’). Salted fish was also imported from the non-localized center in vessels of variant Zeest 75B. In addition, a small amount of purchased olive oil was imported in amphorae of type Zeest 80 from several production sites located in the Aegean and the Black Sea regions. Single items represent variants of amphorae that cannot be correlated with already known types.
In Berezan collection of the Odesa Archaeological Museum of the National Academy of Sciences of Ukraine, no ceramic containers were found, which could be dated only later than 264. However, vessels of types Zeest 72 and Kapitän II could come to Berezan in the 4th century AD.
OS CONTOS CEDRAZIANOS PARA A CONDUÇÃO DE UM ENSINO INTERDISCIPLINAR
Authors: Barbosa Priscila Raiane da Silva , Lira Mirtes Ribeiro de 
Published: July 2022

Resumo: Os contos que compõem a coleção “Outras Histórias da Turma do Xaxado”, escritos por Antônio Cedraz, embasam-se no realismo maravilhoso. Nessas produções, o contexto social do Brasil é revelado por meio da associação entre elementos fantasiosos, provenientes do imaginário dos brasileiros, e aspectos voltados à realidade desse país com destaque ao sertão nordestino. Assim, este estudo tem como objetivo demonstrar como esses contos podem se tornar um excelente recurso pedagógico, capaz de auxiliar uma prática de ensino interdisciplinar condizente com o contexto atual. Nessa perspectiva, além de entreter os leitores, as produções contribuem para a produção de significados que geram conhecimento nas diversas áreas do saber.
Abstract: The tales that compose the collection “Other Stories of the Xaxado’s gang”, written by Antônio Cedraz, are based on wonderful realism. In these productions, the social context of Brazil is revealed through the association between fanciful elements, derived from the imagination of Brazilian people, and aspects focused on the reality of that country, with emphasis on the northeastern backwoods. Thus, this study aims to demonstrate how these stories can become an excellent pedagogical resource, capable of assisting an interdisciplinary teaching practice consistent with the current context. In this perspective, in addition to entertaining readers, the productions contribute to the production of meanings that generate knowledge in the various areas of knowledge.
PALAVRA DENTRO DOS PARÊNTESES - O LUGAR DO NÃO-HETEROSSEXUAL NA BASE NACIONAL COMUM CURRICULAR:
Authors: Baliscei João Paulo , Mochi Luciene Celina Cristina 
Published: July 2022

Este artigo tem como objetivo problematizar as maneiras como as configurações familiares são abordadas enquanto representações na Educação Básica. Organizou-se uma pesquisa com delineamentos bibliográficos e documentais, a partir da qual analisaram-se as menções que a Base Nacional Comum Curricular – BNCC faz sobre “famílias” e “sexualidades”. Debruçou-se sobre os estudos das Relações de Gênero e Estudos da Cultura Visual. Nas considerações finais, levaram-se cinco justificativas para explicar que a BNCC fortalece a heterossexualidade compulsória, e estabeleceram-se relações entre “estar dentro dos parênteses” e estar “dentro do armário”.
EXISTE UMA BNCC NA SSP?
Authors: Ferreira Deyvid Braga , Maria Nogueira Diógenes Elione , Carla Gonçalves Ferreira Geisa 
Published: July 2022

Este artigo objetiva analisar a Matriz Curricular Nacional proposta pela Secretaria Nacional de Segurança Pública (SENASP/MJ), mais especificamente seu objetivo geral de ensino que padroniza as malhas curriculares de todo o País, dos profissionais da área de segurança pública. A metodologia utilizada para desvelar tal problemática foi a pesquisa qualitativa, com revisão bibliográfica. Nossa perspectiva teórica foi a da Análise do Discurso de vertente francesa, que trabalha a relação língua, ideologia e história. Nossa categoria de análise foi a Formação Discursiva. Os resultados desta pesquisa mostraram que tal instrumento de padronização curricular, em vez de apresentar melhoras institucionais, dialoga com os anseios do capital de forma a perpetuar o seu projeto de sociabilidade.
Flipped Well-Plate Hanging-Drop Technique for Growing Three-Dimensional Tumors
Authors: Jeong Yoon , Tin Ashley , Irudayaraj Joseph 
Published: July 2022

Three-dimensional (3D) tumor culture techniques are gaining popularity as in vitro models of tumoral tissue analogues. Despite the widespread interest, need, and present-day effort, most of the 3D tumor culturing methodologies have not gone beyond the inventors’ laboratories. This, in turn, limits their applicability and standardization. In this study, we introduce a straightforward and user-friendly approach based on standard 96-well plates with basic amenities for growing 3D tumors in a scaffold-free/scaffold-based format. Hanging drop preparation can be easily employed by flipping a universal 96-well plate. The droplets of the medium generated by the well-plate flip (WPF) method can be easily modified to address various mechanisms and processes in cell biology, including cancer. To demonstrate the applicability and practicality of the conceived approach, we utilized human colorectal carcinoma cells (HCT116) to first show the generation of large scaffold-free 3D tumor spheroids over 1.5 mm in diameter in single-well plates. As a proof-of-concept, we also demonstrate matrix-assisted tumor culture techniques in advancing the broader use of 3D culture systems. The conceptualized WPF approach can be adapted for a range of applications in both basic and applied biological/engineering research.
Towards Better Governance on Biosafety and Biosecurity: China’s Advances and Perspectives in Medical Biotechnology Legislation
Authors: Xue Yang , Shang Lijun 
Published: July 2022

In this paper, we systematically investigated and assessed China’s evolving medical biotechnology legislative and regulatory regime. 89 laws, rules, measures, guidelines, and views from 1985 to 2022 were systematically analogized and 28 were found to be involved in medical biotechnology legislation, including the recently passed Biosecurity Law. We classified the legislations and performed a comparative analysis for their legal binding based on the legal subject and extent of application, then further analyzes some of the legislative challenges in governing medical biotechnology risks in the context of China’s upgrading its regulatory and legal regime in the last 3 years. We concluded that policymakers in China have now incorporated medical biotechnology-related biosafety and biosecurity into the national strategic goals of a “People-Centered” approach to establish and foster an ecological civilization, particularly in the aftermath of the “He Jiankui affair.” Instead of relying on a patchwork of existing regulations and measures relating to the emerging field of medical biotechnology, China is attempting to integrate a patchwork of existing regulations and measures into a comprehensive legal framework, such as the constitution, National Security Law, Biosecurity Law, administrative regulations, departmental and local rules, and has begun to use the Civil Code and Criminal Law to explicitly identify actions relating to medical biotechnology. In general, China follows the “precautionary principle” as it thinks that uncertainty in science and technology should not be used to justify delaying the adoption of measures to prevent injuries or dangers, stating that whoever advances biotechnology must face the burden of proof of no harm. There would be a need to impose oversight for prevention and precaution if any biotechnology breakthrough that carries risks on which no scientific consensus has been reached. We argued that the “top-down” formulation of general objectives by the active political leadership and “bottom-up” innovation in the implementation are the keys to achieving these goals. Given the rapid advancements in medical biotechnology, countries all over the world must examine the governance landscape around biosafety and biosecurity and quickly consider options for their own comprehensive, credible, and long-lasting regulatory frameworks and experiences learned from China’s governance will help chart a scalable future roadmap.
Regeneration in the Auditory Organ in Cuban and African Dwarf Crocodiles (Crocodylus rhombifer and Osteolaemus tetraspis) Can We Learn From the Crocodile How to Restore Our Hearing?
Authors: Li Hao , Staxäng Karin , Hodik Monika , Melkersson Karl-Gunnar , Rask-Andersen Mathias , Rask-Andersen Helge 
Published: July 2022

Background: In several non-mammalian species, auditory receptors undergo cell renewal after damage. This has raised hope of finding new options to treat human sensorineural deafness. Uncertainty remains as to the triggering mechanisms and whether hair cells are regenerated even under normal conditions. In the present investigation, we explored the auditory organ in the crocodile to validate possible ongoing natural hair cell regeneration.Materials and Methods: Two male Cuban crocodiles (Crocodylus rhombifer) and an adult male African Dwarf crocodile (Osteolaemus tetraspis) were analyzed using transmission electron microscopy and immunohistochemistry using confocal microscopy. The crocodile ears were fixed in formaldehyde and glutaraldehyde and underwent micro-computed tomography (micro-CT) and 3D reconstruction. The temporal bones were drilled out and decalcified.Results: The crocodile papilla basilaris contained tall (inner) and short (outer) hair cells surrounded by a mosaic of tightly connected supporting cells coupled with gap junctions. Afferent neurons with and without ribbon synapses innervated both hair cell types. Supporting cells occasionally showed signs of trans-differentiation into hair cells. They expressed the MAFA and SOX2 transcription factors. Supporting cells contained organelles that may transfer genetic information between cells, including the efferent nerve fibers during the regeneration process. The tectorial membrane showed signs of being replenished and its architecture being sculpted by extracellular exosome-like proteolysis.Discussion: Crocodilians seem to produce new hair cells during their life span from a range of supporting cells. Imposing efferent nerve fibers may play a role in regeneration and re-innervation of the auditory receptors, possibly triggered by apoptotic signals from wasted hair cells. Intercellular signaling may be accomplished by elaborate gap junction and organelle systems, including neural emperipolesis. Crocodilians seem to restore and sculpt their tectorial membranes throughout their lives.
Blood-Based Biomarkers to Search for Atrial Fibrillation in High-Risk Asymptomatic Individuals and Cryptogenic Stroke Patients
Authors: Palà Elena , Bustamante Alejandro , Pagola Jorge , Juega Jesus , Francisco-Pascual Jaume , Penalba Anna , Rodriguez Maite , De Lera Alfonso Mercedes , Arenillas Juan F. , Cabezas Juan Antonio , Pérez-Sánchez Soledad , Moniche Francisco , de Torres Reyes , González-Alujas Teresa , Clúa-Espuny Josep Lluís , Ballesta-Ors Juan , Ribas Domingo , Acosta Juan , Pedrote Alonso , Gonzalez-Loyola Felipe , Gentile Lorente Delicia , Ángel Muñoz Miguel , Molina Carlos A. , Montaner Joan 
Published: July 2022

BackgroundAtrial fibrillation (AF) increases the risk of ischemic stroke in asymptomatic individuals and may be the underlying cause of many cryptogenic strokes. We aimed to test the usefulness of candidate blood-biomarkers related to AF pathophysiology in two prospective cohorts representative of those populations.MethodsTwo hundred seventy-four subjects aged 65–75 years with hypertension and diabetes from the AFRICAT cohort, and 218 cryptogenic stroke patients aged &gt;55 years from the CRYPTO-AF cohort were analyzed. AF was assessed by 4 weeks of monitoring with a wearable Holter device (NuuboTM™). Blood was collected immediately before monitoring started. 10 candidate biomarkers were measured by automated immunoassays (Roche, Penzberg) in the plasma of all patients. Univariate and logistic regression analyses were performed in each cohort separately.ResultsAtrial fibrillation detection rate was 12.4% (AFRICAT cohort) and 22.9% (CRYPTO-AF cohort). 4 biomarkers were significantly increased in asymptomatic individuals with AF [Troponin-T, Angiopoietin-2 (Ang-2), Endocan, and total N-terminal pro-B type natriuretic peptide (NT-proBNP)] and 7 biomarkers showed significantly higher concentrations in cryptogenic stroke patients with AF detection [growth differentiation factor 15, interleukin 6, Troponin-T, Ang-2, Bone morphogenic protein 10, Dickkopf-related protein 3 (DKK-3), and total NT-proBNP]. The models including Ang-2 and total NT-proBNP [AUC 0.764 (0.665–0.863)], and Ang-2 and DKK-3 [AUC = 0.733 (0.654–0.813)], together with age and sex, showed the best performance to detect AF in high-risk asymptomatic individuals, and in cryptogenic stroke patients, respectively.ConclusionBlood-biomarkers, in particular, total NT-proBNP, DKK-3, and Ang-2, were associated with AF reflecting two mechanistically different pathways involved in AF pathophysiology (AF stretch and vascular changes). The combination of these biomarkers could be useful in AF screening strategies in the primary care setting and also for searching AF after cryptogenic stroke.
Pre-existing Proton Pump Inhibitor Treatment and Short-Term Prognosis of Acute Myocardial Infarction Patients
Authors: Xie Juntao , Chen Qingui , He Dejian 
Published: July 2022

IntroductionEvidence suspects proton pump inhibitor (PPI) use is a risk factor of poor prognosis of acute myocardial infarction (AMI). We aimed to investigate the association between pre-existing PPI use before emergency department (ED) visit and short-term prognosis of AMI patients.Materials and MethodsAMI patients admitted to ED were included and categorized as cohorts with or without pre-existing PPI use. Hospital mortality, length of hospital stay, being admitted to intensive care unit (ICU), and length of (total) ICU stay were studied as prognostic outcomes. Multivariable logistic regression or linear regression were used to estimate the associations between pre-existing PPI use and the outcomes after adjusting for potential confounders.ResultsA total of 2001 AMI patients were included. No significant difference was found in hospital mortality and length of ICU stay between cohorts; patients with pre-existing PPI use showed a significantly longer length of hospital stay (median 3.81 vs. 3.20 days, P = 0.002) but lower proportion of being admitted to ICU (25.59% vs. 40.83%, P &lt; 0.001) compared to those without pre-existing PPI use. Pre-existing PPI use was not associated with hospital mortality [odds ratio (OR) 1.08, 95% confidence interval (CI) 0.58–1.99], length of hospital stay (β = 0.23, 95% CI −0.35 to 0.82), and length of ICU stay (β = −0.18, 95% CI −1.06 to 0.69), but was statistically significantly associated with lower risk of being admitted to ICU (OR 0.69, 95% CI 0.52–0.92).ConclusionThe current study does not support newly diagnosed AMI patients with pre-existing PPI use before ED visit would experience worse short-term prognosis than those without.
Precipitation Trends Analysis Using Gridded Dynamic Sampling Zones: Case Study Yangtze Delta Megalopolis
Authors: Liu Xiaolong , Fu Dafang , Zevenbergen Chris , Yu Meixiu , Kumar Alagarasan Jagadeesh 
Published: July 2022

As a result of the fast growth of remote sensing and data assimilation technology, many global land use land cover (LULC) and climate reanalysis data sets have been used to advance our understanding of climate and environmental change. This paper investigates the precipitation variations of the Yangtze Delta Megalopolis by using precipitation reanalysis data under conditions of dynamic urban sprawl. Compared with current precipitation characteristic analyses, which are often based on a limited number of ground rainfall stations, the approach followed in this study comprises a grid-based statistical method using large sets of samples with a uniform distribution and a same representative grid area. This novel approach of dynamic sampling is applied in this study to overcome the temporal and spatial inconsistency of stationary sampling. This approach allows to examine the impact of urbanization on regional precipitation characteristics. The Yangtze Delta Megalopolis (YDM) region, one of the most developed regions in China, was selected as a case study to evaluate the impact of urbanization on subsequent precipitation features. The results reveal that the annual total precipitation (TP) and the maximum daily precipitation (MDP) in both urban and non-urban areas of the YDM region generally have increased during the past 30 years. Hence, the region has become increasingly humid. Extrema of annual MDP and TP show obvious spatial characteristics, in which most maxima are located in the southern part of YDM while minima are more concentrated in the northern part. This newly developed approach has potentials for application in studies where underlying surface features exhibit rapid alterations. The findings of this case study provide relevant information for planning and design of regional water resources management, flood risk management, and planning of the urban drainage system of the YDM region.