bluuebunny/crossref_metadata_2025_split huggingface dataset:
DEVELOPMENT OF SMALL AND MEDIUM-SIZED BUSINESSES IN AKTOBE REGION
Authors: Балгинова К.М. , Шакибаев М.К. , Сагиндыкова Г.М. , Юсупов У.Б. , Balginova K. , Shakibaev M. , Sagindykova G. , Yussupov U. 
Published: August 2022

Қазіргі уақытта шағын және орта кәсіпкерлік өңірдің қажеттіліктеріне айқын бағдарланған ұлттық және өңірлік экономиканың ажырамас бөлігі болып табылады. Сондықтан шағын және орта кәсіпкерлікті дамыту жеке алынған өңір үшін де, жалпы ел үшін де бірдей маңызды. Жетекші шет елдердің тәжірибесі халықты жұмыспен қамтуда, нарық қажеттіліктерін қанағаттандыруда және өңірлік және ұлттық экономиканы дамытуда шағын және орта кәсіпкерліктің қоғамдық маңыздылығын растайды. Бәсекелестік пен жаһанданудың шиеленісуінің қазіргі жағдайында мемлекет кәсіпкерлікті қолдау мен дамыту үшін мүмкіндіктерді қарастырып, іске асыра отырып және қаражат бөле отырып, бір мезгілде көптеген елдердің дамуын қамтамасыз етеді. Шағын және орта кәсіпкерлік белгілі бір табыстарға жетті, алайда Қазақстанда ол экономиканың маңызды секторы ретінде қоғамның дамуына әлі де ықпал ете алмайды. Ел экономикасындағы шағын және орта кәсіпкерліктің рөлін және оның қолда бар әлеуетін елемеу стратегиялық есептеу сипатына ие болады. Сондықтан шағын және орта кәсіпкерлікті қолдаудың тиімді мемлекеттік саясатын әзірлеу, оның жұмыс істеуі үшін қолайлы жағдайлар жасау мемлекеттің экономикалық саясатының маңызды бөлігі болып табылады. Мақалада Ақтөбе облысының мысалында шағын және орта кәсіпкерліктің жағдайы мен дамуы зерттелген. Мемлекет тарапынан көрсетілетін қолдау қарастырылды
Currently, small and medium-sized enterprises are an integral part of the national and regional economy, clearly focused on the needs of the region. Therefore, the development of small and medium-sized businesses is equally important, both for a particular region and for the country as a whole.The experience of leading foreign countries also confirms the social importance of small and medium-sized enterprises in providing employment, meeting market needs and developing regional and national economies. In modern conditions of increasing competition and globalization, the state, considering and realizing opportunities and allocating funds to support and develop entrepreneurship, simultaneously ensures the development of many countries.Small and medium-sized enterprises have achieved some success, but in Kazakhstan, as the most important sector of the economy, it still does not have an impact on the development of society. Ignoring the role of small and medium-sized enterprises in the country's economy and its existing potential, acquires the character of a strategic miscalculation. Therefore, the development of an effective state policy to support small and medium-sized businesses, the creation of favorable conditions for its functioning is an important part of the economic policy of the state.The article examines the state and development of small and medium-sized businesses on the example of the Aktobe region. The support provided by the state is considered.
Persepsi Orang Tua Dalam Pembelajaran Daring Di Dukuh Beji Selama Pandemi Covid-19
Authors: Arsena Alvian , Erik Aditia Ismaya  , Muhammad Noor Ahsin  
Published: August 2022

Terjadinya pandemi virus Covid-19yang berdampak pada seluruh masyarakat salam satunya adalah pendidikan. karena situasi yang menghawatirkan pemerintah mengeluarkan kebijakan untuk belajar di rumah atau daring hal tersebut menimbulkan berbagai persepsi pada orang tua. Berdasarkan observasi yang di lakukan di dukuh Beji orang tua memilik kesulitan dalam mendampingi anak saat belajar daring dikarenakan kesibukan oarng tua dalm bekerja, kurang paham dengan cara kerja pembelajaran daring, dan permaslahan dengan jaringan yang susah.tujuan penenelian ini adalah untuk mengetahui persepsi orang tua pada pembelajaran daring, dampak apa saja yang di rasakan orang tua, dan upaya dallam mendampingi anak belajar daring.. Hasil dari penelitian tentang dilaksanakannya pembelajaran daring orang tua memiliki persepsi yang berbeda ada yang setuju dan tidak dengan adanya daring, setuju karena berkat adanya daring orang tua mersa lebih aman anaknya belajar di rumah, Anak masih bisa belajar walaupun tidak tatap muka langsung di sekolah dan daring membuat pembelajaran menjadi lebih cepat dan mudah. Dan yang membuat tidak sejutu Pertama orang tua kesulitan membagi waktunya antara pekerjaan dan mendampingi anak belajar, Anak kesusahan memahami materi tua kesusahan dalam mengikuti pembelajaran daring.
Kata Kunci: Persepsi orang tua; Pembelajaran Daring; COVID-19
Studi Korelasi Antara Literasi Digital Dan Minat Belajar Siswa Pada Era Pandemi Covid-19
Authors: Melati Dita Puti , Abdul Rahman  , Nurhadi  
Published: August 2022

Abstract :
Learning interest deserves attention by teachers, schools and societies. Digital literacy should be the solution. The pandemic Covid-19 has caused downgrading student learning interest. The research objective was to analyse the correlation between digital literacy and student learning interest. This research found that the more variety of digital literacy activities the higher students’ learning interest. Digital literacy platforms allow students to access and apply technology in obtaining, using, and sharing data dan information for learning. Quantitative data were collected from 298 students in Surakarta. Findings showed that rxy.678 meaning that the correlation between digital literacy(X) and learning interest(Y) is positively significant. Moreover we found that the rxy.632 for the classroom digital literacy (X1), rxy.609 for the school digital literacy (X2), and rxy.532 for social digital literacy (X3), all findings show positive contribution to learning interest. Thus, teachers, parents, and society can improve learning interest. We recommend that digital literacy should work in class, schools and community.
Keywords: Digital literacy, student learning interest, pandemic Covid-19.
Abstrak :
Minat belajar patut mendapat perhatian guru, sekolah dan masyarakat. Literasi digital harus menjadi solusi. Pandemi Covid-19 menyebabkan menurunnya minat belajar siswa. Penelitian ini bertujuan untuk menganalisis hubungan literasi digital dengan minat belajar siswa. Penelitian ini menemukan bahwa semakin beragam kegiatan literasi digital semakin tinggi minat belajar siswa. Platform literasi digital memungkinkan siswa untuk mengakses dan menerapkan teknologi dalam memperoleh, menggunakan, dan berbagi data dan informasi untuk pembelajaran. Data kuantitatif dikumpulkan dari 298 siswa di Surakarta. Hasil penelitian menunjukkan bahwa rxy.678 yang berarti korelasi antara literasi digital (X) dan minat belajar (Y) signifikan secara positif. Selain itu kami menemukan bahwa rxy.632 untuk literasi digital kelas (X1), rxy.609 untuk literasi digital sekolah (X2), dan rxy.532 untuk literasi digital sosial (X3), semua temuan menunjukkan kontribusi positif terhadap minat belajar. Dengan demikian, guru, orang tua, dan masyarakat dapat meningkatkan minat belajar. Kami merekomendasikan bahwa literasi digital harus bekerja di kelas, sekolah dan masyarakat.
Kata Kunci: Literasi digital, minat belajar, pandemic Covid-19
Downstream Effects of Industrial Effluents Discharge on Some Physicochemical Parameters and Water Quality Index of River Rido, Kaduna State, Nigeria
Authors: Butu Ali Williams , Emeribe Chukwudi Nnaemeka , Muoka Ijeoma Obianuju , Emeribe Oluchi Favour , Ogbomida Emmanuel Temiotan 
Published: August 2022

The effects of industrial effluent discharge on the water quality of River Rido in Kaduna South, Kaduna State, were examined. These include the Northern Noodles discharge point, the Kaduna Refinery discharge point, and points downstream of the River Rido. An interval of 100m between sampling points was established to achieve an even representation of sampling points. The physico-chemical parameters investigated include pH, free dissolved carbon dioxide, alkalinity, hardness, sodium, electrical conductivity, Turbidity, total suspended solids, total phosphate, nitrate, sulfate, and dissolved oxygen. Mean levels of turbidity Total suspended solids and total phosphate at effluent discharge points, as well as in most areas downstream of the study area, were generally above permissible limits for drinking water. Statistical differences were observed in the concentration levels of investigated parameters between the control point and effluent discharge points, as well as between the control point and areas downstream of the study area. However, concentration levels were observed to be similar between discharge points and areas downstream of the study area, an indication of contamination downstream by effluent discharge upstream. Notwithstanding, the water quality index of physico-chemical parameters at both effluent discharge points and areas downstream of River Rido shows that the quality of the river ranged from good to excellent at effluent discharge points and areas downstream of River Rido, respectively. This might be attributed to the effect of dilution from rainfall. It is therefore recommended that wastewater effluent from the refinery and northern noodles be properly treated before discharged into the study area.
INVESTIGATION OF LEVEL OF SERUM INTERLEUKİN 17 IN AGE-RELATED MACULAR DEGENERATİON
Authors: TÜRKER ASLAN Hatice , ATEŞ Ömer 
Published: August 2022

Age-related macular degeneration (AMD) is a non-recyclable visual disorder among elderly people worldwide and AMD is one of the leading causes of blindness. Former studies, interleukins were found to be effective in patients with AMD. This study’s object, the relationship of serum interleukin 17 with age-related macular degeneration was evaluated.
Interleukin 17 levels were measured by ELISA method using the blood sera of 100 patients diagnosed with age-related macular degeneration and 100 healthy individuals in the control group.
Acording to the results of the study, the differences between the patient and control groups of interleukin 17 levels was found statistically significant (p:0,001; p > 0,05). It was found that gender difference in patients did not affect interleukin 17 levels (p=0,649; p > 0,05).
In the study, there was a significant relationship between age-related macular degeneration and serum interleukin 17.
Neuroinflammation in neuronopathic Gaucher disease: Role of microglia and NK cells, biomarkers, and response to substrate reduction therapy
Authors: Boddupalli Chandra Sekhar , Nair Shiny , Belinsky Glenn , Gans Joseph , Teeple Erin , Nguyen Tri-Hung , Mehta Sameet , Guo Lilu , Kramer Martin L , Ruan Jiapeng , Wang Honggge , Davison Matthew , Kumar Dinesh , Vidyadhara DJ , Zhang Bailin , Klinger Katherine , Mistry Pramod K 
Published: August 2022

Background:Neuronopathic Gaucher disease (nGD) is a rare neurodegenerative disorder caused by biallelic mutations in GBA and buildup of glycosphingolipids in lysosomes. Neuronal injury and cell death are prominent pathological features; however, the role of GBA in individual cell types and involvement of microglia, blood-derived macrophages, and immune infiltrates in nGD pathophysiology remains enigmatic.Methods:Here, using single-cell resolution of mouse nGD brains, lipidomics, and newly generated biomarkers, we found induction of neuroinflammation pathways involving microglia, NK cells, astrocytes, and neurons.Results:Targeted rescue of Gba in microglia and neurons, respectively, in Gba-deficient, nGD mice reversed the buildup of glucosylceramide (GlcCer) and glucosylsphingosine (GlcSph), concomitant with amelioration of neuroinflammation, reduced serum neurofilament light chain (Nf-L), and improved survival. Serum GlcSph concentration was correlated with serum Nf-L and ApoE in nGD mouse models as well as in GD patients. Gba rescue in microglia/macrophage compartment prolonged survival, which was further enhanced upon treatment with brain-permeant inhibitor of glucosylceramide synthase, effects mediated via improved glycosphingolipid homeostasis, and reversal of neuroinflammation involving activation of microglia, brain macrophages, and NK cells.Conclusions:Together, our study delineates individual cellular effects of Gba deficiency in nGD brains, highlighting the central role of neuroinflammation driven by microglia activation. Brain-permeant small-molecule inhibitor of glucosylceramide synthase reduced the accumulation of bioactive glycosphingolipids, concomitant with amelioration of neuroinflammation involving microglia, NK cells, astrocytes, and neurons. Our findings advance nGD disease biology whilst identifying compelling biomarkers of nGD to improve patient management, enrich clinical trials, and illuminate therapeutic targets.Funding:Research grant from Sanofi; other support includes R01NS110354.
Brides of the Buddha: Nuns’ Stories from the Avadānaśataka. By Karen Muldoon-Hules
Authors: Langenberg Amy Paris 
Published: August 2022

Brides of the Buddha: Nuns’ Stories from the Avadānaśataka. By Karen Muldoon-Hules. New
York: Lexington Books, 2017. Pp. xii + 227. $100.
Heavy Metals and Health Risk Burden, How Safe is the Consumer Population?: A Study on the Heavy Metal Content of Soybeans Cultivated in Katsina State, North West Nigeria
Authors: Yaradua A. I. , Bungudu J. I. , Shuaibu L. , Alhassan A. J. , Nasir A. , Bello U. , Usman A. , Suleiman Z. A. , Abdullahi A. , Muhammad M. M. , Yaradua A. I. , Yaradua I. A. 
Published: August 2022

The level of heavy metals in soybeans samples were evaluated to ascertain their likely health risks to the Katsina State populace. Atomic absorption spectrometry method was employed for the evaluation, while the three senatorial zones of the state were used for sampling. Using methods adapted from the United States Environmental Protection Agency (US EPA), the health risks to the population from the heavy metals in the samples were determined. The results have revealed the mean concentration (mg/kg) in decreasing order of concentrations to be for Zn (range: 1.204-1.432), Pb (range: 0.658-0.998), Fe (range: 0.563-0.687), Cr (range: 0.128-0.151) and Cd (range: 0.041-0.046), with the concentrations of Mn and Ni below the level of detection. The computed non-carcinogenic health risks from consumption of the samples were below 1 (THQ and HI>1). The cancer risk to the population lies beyond the threshold limit with the heavy metal Pb being the major contributor to the violation. It may be presumed that the Soybean samples in the study may add to the cancer manifestations in the population.
Non-carcinogenic and Carcinogenic Health Risk Evaluation from Fish Contaminated with Heavy Metals
Authors: Yaradua A. I. , Shuaibu L. , Bungudu J. I. , Nasir A. , Usman A. , Abdullahi A. , Muhammad M. M. , Sani A. S. , Yaradua I. A. , Matazu H. K. 
Published: August 2022

The pollution of water bodies with heavy metals can result into the possible contamination of freshwater fish. The levels of the heavy metals Pb, Fe, Cu, Zn, Ni and Cd were investigated in fish samples (Ameiurus nebulosus, Pylidictis olivaris, Tilapia zilli, Clarias gariepinus) collected from Kwanar-Are dam located at Rimi local government area Katsina State, Nigeria and the health risks of the evaluated heavy metals were estimated. The mean concentration ranges of Pb, Fe, Cu, Zn and Cd were (0.0851-0.4919, 0.3095-0.5039, 0.0366-0.0589, 0.1066-0.3015, 0.1048-0.1417, 0.0128-0.0686 mg/kg) respectively. The risk assessment for non-carcinogenic exposure effect showed that there was no health risk associated with these elements through consumption of the fish samples to the consumer population. However the risk assessment for carcinogenic exposure effect has revealed that the incremental lifetime cancer risk (ILCR) and the cumulative lifetime cancer risks (∑ILCR) were all above the safe limit for cancer in the children and the adults population for all the fish samples evaluated. The heavy metal Ni presented the greatest cancer risk and the fish sample Clarias gariepinus having the highest cancer risk. There is a degree of concern for consumption of the fish samples for their potentials to contribute to the population cancer risk load.
Best Row Ratio Combinations of Agronomic Crops in the Intercropping System: An Overview
Authors: Chaudhary Manthan , Kumar Rajan , Yadav Abhinav , Maurya Shravan Kumar , Sahu Sandeep , Tiwari Ankit 
Published: August 2022

The quality of soil and water, as well as the preservation of biodiversity, are negatively impacted by intensive agricultural systems. High biodiversity regulates how intercropping evolves. Contrastingly, monocultures are used in intensive agriculture systems, along with substantial inputs of chemical fertilizers and pesticides. One strategy for boosting diversity in an agricultural ecosystem is intercropping. Intercropping systems improve environmental harmony, increased resource use efficiency, enhance the quantity and quality of goods, and less damage from pests, diseases, and weeds. Leguminosae family plants are preferable for intercropping even though they fix more biological nitrogen, thus enriching soil fertility. Intercropping is significant in many subsistence or low-input/resource-limited agricultural systems, which are on the periphery of modern intensive agriculture. Thus, opting for suitable combinations of crops with an optimum row ratio will be more profitable, ecologically sound, and economically viable.
Some Aspects of Blockchain-Enabled Radio Access Networks (B-RAN) Modeling: Review and Theoretical Study
Authors: Kontorovich V. 
Published: August 2022

The impressive growth of the demand for wireless services for 5G and beyond, particularly encouraged by the Internet of Things, Internet of Everything, etc., raised up the importance of the problems related to the drastic increase (among others) of spectrum efficiency of the systems. In this regard two opportunistic trends were recently discussed by practical professionals and academicians: non-orthogonal spectrum sharing (NOMA transmission) for user equipment (UE) at physical layer level and decentralized Blockchain-enabled Radio Access (B-RAN) paradigm at network layer label. Both of them promise a significant growth on the transmission rate and the spectrum efficiency with low latency, etc. not only for 5G networks, but further, towards 6G networks and so on.
Moreover, it is a fact that the number of published works for B-RAN (some of them considered hereafter) is very impressive, however, the attention to its modeling aspects is rather limited.
The presented material is dedicated to present an approach for the practical small-scale modeling for the case of high-dimensional B-RAN based on continuous-time Markov processes with discrete set of states (N>>1) and self-similar processes for its traffic modeling.
Type of School and the Level of Students’ Academic Achievement in Marakwet East Sub County
Authors: K. Kisigot Charles 
Published: August 2022

The major purpose of this study was to assess the effect of type of school on the level of students’ academic achievement in Marakwet East Sub County.
Academic achievements in secondary schools have remained low with major disaprities between the boys and girls schools in Marakwet East Sub-County.
The study utilized the Causal comparative approach. The study was undertaken in Public Secondary Schools in Marakwet East, Elgeyo County Kenya between January 2021 to February 2021.
Purposive, stratified and simple random sampling was used to sample 3 boys’ school, 3 girls school and 4 mixed schools. Findings showed the one-way between groups analysis of variance was F (2, 7) = 10.936, p.05. As a result, the null hypothesis which was stated as that there is no link between school type and academic achievement was rejected.In conclusion,the present study rejected the null hypothesis and concludes that the relationship is statistically significant. The sample data support the notion that the relationship between the independent variable and dependent variable exists in the population of secondary schools in Marakwet East. Thus the hypothesis (Ho1) was rejected. There was a link between academic achievement and the type of school. Boys' and girls' schools, in particular, performed better than mixed schools.
Suppression of Lipopolysaccharide‐Induced Sepsis by Tetrahedral Framework Nucleic Acid Loaded with Quercetin
Authors: Liu Zhiqiang , Chen Xingyu , Ma Wenjuan , Gao Yang , Yao Yangxue , Li Jiajie , Zhang Tianxu , Qin Xin , Ge Yichen , Jiang Yueying , Lin Yunfeng 
Published: August 2022

AbstractSepsis has affected millions of people worldwide with high mortality rate and lack of effective strategies. Previous studies have reported that quercetin (Que) can attenuate lipopolysaccharide (LPS)‐Induced sepsis. However, for poor water solubility, low bioavailability, and instability, the application of Que is limited. Hence, a nano‐system is constructed to deliver Que based on tetrahedral framework nucleic acid (tFNA), namely tFNA‐Que. For the anti‐inflammatory, anti‐oxidant, and delivery performance of tFNA, tFNA is designed as the effective carrier to deliver Que. The tFNA‐Que possesses the simple synthesis method, stable performance, good biocompatibility, favorable water solubility, excellent anti‐inflammatory, and anti‐oxidation property. As a result, tFNA‐Que can attenuate LPS‐Induced systemic inflammation and multiple organ injury of mice. In brief, the synthesis of tFNA‐Que provides a simple and effective synergistic delivery nano‐system, which may be a promising candidate for sepsis.
Monodispersed FeS2 Electrocatalyst Anchored to Nitrogen‐Doped Carbon Host for Lithium–Sulfur Batteries
Authors: Sun Weiwei , Liu Shuangke , Li Yujie , Wang Danqin , Guo Qingpeng , Hong Xiaobin , Xie Kai , Ma Zhongyun , Zheng Chunman , Xiong Shizhao 
Published: August 2022

AbstractDespite their high theoretical energy density, lithium–sulfur (Li–S) batteries are hindered by practical challenges including sluggish conversion kinetics and shuttle effect of polysulfides. Here, a nitrogen‐doped continuous porous carbon (CPC) host anchoring monodispersed sub‐10 nm FeS2 nanoclusters (CPC@FeS2) is reported as an efficient catalytic matrix for sulfur cathode. This host shows strong adsorption of polysulfides, promising the inhibition of polysulfide shuttle and the promoted initial stage of catalytic conversion process. Moreover, fast lithium ion (Li‐ion) diffusion and accelerated solid–solid conversion kinetics of Li2S2 to Li2S on CPC@FeS2 host guarantee boosted electrochemical kinetics for conversion process of sulfur species in Li–S cell, which gives a high utilization of sulfur under practical conditions of high loading and low electrolyte/sulfur (E/S) ratio. Therefore, the surfur cathode (S/CPC@FeS2) delivers a high specific capacity of 1459 mAh g−1 at 0.1 C, a stable cycling over 900 cycles with ultralow fading rate of 0.043% per cycle, and an enhanced rate capability compared with cathode only using carbon host. Further demonstration of this cathode in Li–S pouch cell shows a practical energy density of 372 Wh kg−1 with a sulfur loading of 7.1 mg cm−2 and an E/S ratio of 4 µL mg−1.