bluuebunny/crossref_metadata_2025_split huggingface dataset:
Free Energy Wells and Overlap Gap Property in Sparse PCA
Authors: Arous Gérard Ben , Wein Alexander S. , Zadik Ilias 
Published: September 2022

AbstractWe study a variant of the sparse PCA (principal component analysis) problem in the “hard” regime, where the inference task is possible yet no polynomial‐time algorithm is known to exist. Prior work, based on the low‐degree likelihood ratio, has conjectured a precise expression for the best possible (subexponential) runtime throughout the hard regime. Following instead a statistical physics‐inspired point of view, we show bounds on the depth of free energy wells for various Gibbs measures naturally associated to the problem. These free energy wells imply hitting time lower bounds that corroborate the low‐degree conjecture: we show that a class of natural MCMC (Markov chain Monte Carlo) methods (with worst‐case initialization) cannot solve sparse PCA with less than the conjectured runtime. These lower bounds apply to a wide range of values for two tuning parameters: temperature and sparsity misparametrization. Finally, we prove that the overlap gap property (OGP), a structural property that implies failure of certain local search algorithms, holds in a significant part of the hard regime. © 2022 Wiley Periodicals, Inc.
An optimal self adaptive deep neural network and spine‐kernelled chirplet transform for image registration
Authors: Senthil Pandi S. , Senthilselvi A. , Maragatharajan M. , Manju I. 
Published: September 2022

SummaryImage registration is one of the image processing techniques that align more than two images of a similar scene captured under different perspectives at different intervals of time. In demographical research, the image registration process assists to study differences in the structure of brain tissue. Due to enhanced technological advancements, numerous image registration methods have been established. On the other hand, these traditional techniques face few real‐time challenges while processing huge input data. In addition to this, uncertainty analysis becomes a crucial step in medical applications which is utilized to judge whether the registration result is valuable or not. The high percentage of uncertainty than the threshold makes the registration result abnormal. Therefore, to conquer such circumstances, this research work proposed a modified spine‐kernelled chirplet transform (MCST) based optimal Self‐Adaptive Deep Neural Network (SADNN) which focuses mainly on enhancing registration accuracy by reducing the uncertainties of registration results. The experimental analysis is conducted and from the evaluation results, the proposed MCST‐based optimal SADNN technique outperforms existing techniques in terms of accuracy, specificity, sensitivity, F‐measure, and DICE values. Moreover, the proposed method achieves 97.2% accuracy for accurate image registration.
A survey on recommendation in process mining
Authors: Yari Eili Mansoureh , Rezaeenour Jalal 
Published: September 2022

SummaryRecommender systems have been widely applied in several domains to make informed decisions by recommending items that might be of interest. Considering recommendation during business process execution is also highly advantageous as the efficient suggestions about possible activities or resources can impact process performance. However, the deployment of the recommendation frameworks in process mining still needs more investigations to identify the current challenges to enable the practical application of research findings and ensure a large‐scale adoption of this technique. Accordingly, a systematic review is conducted to provide a taxonomy of the published studies on process‐aware recommender systems based on specified criteria, including the type and perspective of recommendation, a list of datasets and evaluation metrics used in the setting of PARS, implementation environments, and different algorithms used in PARS. In this regard, there are various insights extracted from this study: (i) Most studies in the business process analysis domain are of descriptive and predictive nature, (ii) recommendation in process mining is an emerging research area that is being evolving; the majority of proposals relate to 2015 and after that, and (iii) due to the lack of common evaluation protocol, datasets, and metrics, most studies are validated through experiments and prototyping, with less tendency to the practical implementation of a solution regarding real scenarios.
Successive Cleavage and Reconstruction of Lignin β‐O‐4 Models and Polymer to Access Quinoxalines
Authors: Liu Yuxuan , Luo Qi , Qiang Qian , Wang Hua , Ding Yangming , Wang Chao , Xiao Jianliang , Li Changzhi , Zhang Tao 
Published: September 2022

AbstractThe construction of N‐heterocyclic compounds from lignin remains a great challenge due to the complex lignin structure and the involvement of multiple steps, including the cleavage of lignin C−O linkages and the formation of heterocyclic aromatic rings. Herein, the first example of KOH mediated sustainable synthesis of quinoxaline derivatives from lignin β‐O‐4 model compounds in a one‐pot fashion under transition‐metal‐free conditions has been achieved. Mechanistic studies suggested that this transformation includes highly coupled cascade steps of cleavage of C−O bonds, dehydrative condensation, sp3C−H bond oxidative activation, and intramolecular dehydrative coupling reaction. With this protocol, a wide range of functionalized quinoxalines, including an important drug compound AG1295, were synthesized from lignin β‐O‐4 model compounds and β‐O‐4 polymer, showcasing the application potential of lignin in pharmaceutical synthesis.
A novel bi‐directional high‐gain DC‐DC converter with optimum number of components
Authors: Krishna Bekkam , Karthikeyan V. 
Published: September 2022

AbstractMost emerging applications of battery energy storage systems, fuel cells, and unified power supply (UPS) applications require essential bi‐directional power capability with a high conversion ratio. It supports the integration of the high‐voltage DC‐bus with an energy storage unit or fuel cell. In order to meet this requirement, this paper proposes a novel nonisolated high‐gain DC‐DC converter with bi‐directional power flow capability. This converter is configured with a hybrid structure with a combination of the switched capacitor (SC) and switched inductor (SI) techniques. Moreover, this converter can attain extreme voltage gain with less number of semiconductors and passive components. As a result, the converter cost gets reduced and achieves a wide range of voltage gain at a lesser duty ratio. Furthermore, steady‐state analysis and performance of the proposed topology and its characteristics were presented in this paper. Additionally, a detailed comparative analysis was presented with the most recent literature. Finally, a 500‐W experimental prototype has been fabricated to authorize the performance, feasibility, and analytical waveforms with experimental results.
Simultaneous wireless information and power transfer in resonant beam charging
Authors: Ali Ehab , Jibreel Nareeman , Rajab Zakariya , Younis Abdelhamid , Mesleh Raed 
Published: September 2022

SummaryFSO links have attracted a significant amount of interest in the recent years driven by the paramount importance of their license‐free spectrum and ease of deployment in wireless networks. Besides, the energy harvesting (EH) paradigm allows recharging terminals via ambient and/or external sources and prolongs battery lifetime operation. Thereby, facilitating free space optical (FSO) in EH networks creates potential scenarios for the future sixth‐generation (6G) communication systems. In this study, an EH system performing simultaneous wireless information and power transfer (SWIPT) while adopting FSO and resonant beam charging (RBC), RBC–SWIPT system is thoroughly analyzed. The performance of RBC‐SWIPT system is analyzed through Monte Carlo simulations, where average bit error ratio (ABER) and energy efficiency (EE) are studied and evaluated. In addition, channel capacity is derived along with the mutual information and studied over indoor line of sight (LOS) optical channel. Monte Carlo simulation results corroborate the accuracy of the derived formulas.
Breast implant‐associated anaplastic large‐cell lymphoma: A series of two case reports diagnosed by cytopathology
Authors: Hrones Morgan , Harigopal Malini , Xu Mina , Abi‐Raad Rita 
Published: September 2022

AbstractBreast implant‐associated anaplastic large‐cell lymphoma (BIA‐ALCL) is a rare T‐cell lymphoma with a good prognosis. It occurs in association with textured breast implants. Its most common presentation is a late‐onset peri‐implant effusion. We present two cases of BIA‐ALCL diagnosed by cytopathological examination of the fluid collection and describe the cytopathologic findings. Both patients were disease free after implant removal. This report highlights the contribution of the cytopathologic analysis to early diagnosis and definite treatment of BIA‐ALCL.
Emotional expression visual mismatch negativity in children
Authors: Kovarski Klara , Charpentier Judith , Houy‐Durand Emmanuelle , Batty Magali , Gomot Marie 
Published: September 2022

AbstractDetection of changes in facial emotions is crucial to communicate and to rapidly process threats in the environment. This function develops throughout childhood via modulations of the earliest brain responses, such as the P100 and the N170 recorded using electroencephalography. Automatic brain signatures can be measured through expression‐related visual mismatch negativity (vMMN), which reflects the processing of unattended changes. While increasing research has investigated vMMN processing in adults, few studies have been conducted on children. Here, a controlled paradigm previously validated was used to disentangle specific responses to emotional deviants (angry face) from that of neutral deviants. Latencies and amplitudes of P100 and N170 both decrease with age, confirming that sensory and face‐specific activity is not yet mature in school‐aged children. Automatic change detection‐related activity is present in children, with a similar vMMN pattern in response to both emotional and neutral deviant stimuli to what previously observed in adults. However, vMMN processing is delayed in children compared to adults and no emotion‐specific response is yet observed, suggesting nonmature automatic detection of salient emotional cues. To our knowledge, this is the first study investigating expression‐related vMMN in school‐aged children, and further investigations are needed to confirm these results.
Chronic hyperglycemia drives alterations in macrophage effector function in pulmonary tuberculosis
Authors: Panda Sudhasini , Seelan Diravya M , Faisal Shah , Arora Alisha , Luthra Kalpana , Palanichamy Jayanth Kumar , Mohan Anant , Vikram Naval K , Gupta Neeraj Kumar , Ramakrishnan Lakshmy , Singh Archana 
Published: September 2022

ABSTRACTDiabetes mellitus (DM) alters immune responses and given the rising prevalence of DM in tuberculosis (TB) endemic countries; hyperglycemia can be a potential risk factor for active TB development. However, the impact of hyperglycemia on TB‐specific innate immune response in terms of macrophage functions remains poorly addressed. We assessed macrophage effector functions in uncontrolled DM patients with or without TB infection (PTB+DM and DM), non‐diabetic TB patients (PTB), and non‐diabetic‐uninfected controls. Phagocytic capacity against BCG and surface expression of different pattern recognition receptors (PRRs) (CD11b, CD14, CD206, MARCO, and TLR‐2) were measured via flow cytometry. Effector molecules (ROS and NO) required for bacterial killing were assessed via DCFDA and Griess reaction respectively. A systematic dysregulation in phagocytic capacity with concurrent alterations in the expression pattern of key PRRs (CD11b, MARCO, and CD206) was observed in PTB+DM. These altered PRR expressions were associated with decreased phagocytic capacity of macrophages. Similarly, ROS was aberrantly higher while NO was lower in PTB+DM. These altered macrophage functions were positively correlated with increasing disease severity. Our results highlight several key patterns of immune dysregulation against TB infection under hyperglycemic conditions and highlight a negative impact of hyperglycemia with etiology and progression of TB.
Pd‐Catalyzed MIA‐Directed Acetoxylation of Benzylamines and Computational Study
Authors: Meng Yue‐Ning , Zhao Shi‐Chen , Liu Peng‐Yu , Hu Dianwen , Wang Shuai , He Yu‐Peng , Yu Fang 
Published: September 2022

AbstractThe direct acetoxylation of substituted benzylamines has been accomplished through methoxyiminoacyl (MIA)‐mediated Pd‐catalyzed C−H functionalization. A diverse array of phenylalanine substrates is amenable to this protocol, providing acetoxylation benzylamine derivatives with good to high efficiency. Computational results revealed that HOAc enhanced the stability of Pd−O bond, which obviously accelerate the reductive elimination step of the acetoxylation process.
Cascaded line‐of‐sight channel estimation for reconfigurable intelligent surface aided multi‐user uplink transmissions
Authors: Xu Yicheng , Chu Hongyun , Xu Pingping 
Published: September 2022

AbstractThe reconfigurable intelligent surface (RIS) is capable of remolding the wireless propagation environment, and thus it is assumed as a key technology to enable the potentials of intelligent communications. For the RIS enabled multi‐user systems, channel estimation is rather challenging due to the passivity of the RIS without signal processing capability, where the channel is cascaded of the base station (BS)‐RIS and the RIS‐user equipments (UEs) paths. In this article, we propose an off‐grid channel estimation method for the RIS enabled multi‐user transmissions, exploiting the cascaded sparsity in the UEs‐RIS‐BS channel model. Specifically, we first reveal the cascaded sparsity, that is, the sparsity exists in the hybrid angular domains of UEs‐RIS and RIS‐BS separated channel. Then, we formulate the cascaded channel estimation problem as a semi‐definite program using ‐type atomic norm minimization and extract the channel parameters using subspace resolution technologies. Simulation results show that the proposed channel estimator achieves higher performance compared with the existing art‐of‐states.
Panax ginseng abuse exhibits a pro‐inflammatory effect by activating the NF‐κB pathway
Authors: Deng Wenjun , Liu Hangxiu , Guo Lanping , Liu Yongzhong , Ma Zhaocheng 
Published: September 2022

AbstractP. ginseng (Panax ginseng C. A. Meyer) is a well‐known traditional medicine that has been used for thousands of years to treat diseases. However, “ginseng abuse syndrome” (GAS) often occurs due to an inappropriate use such as high‐dose or long‐term usage of ginseng; information about what causes GAS and how GAS occurs is still lacking. In this study, the critical components that potentially caused GAS were screened through a step‐by‐step separation strategy, the pro‐inflammatory effects of different extracts on messenger RNA (mRNA) or protein expression levels were evaluated in RAW 264.7 macrophages through quantitative real‐time polymerase chain reaction (qRT‐PCR) or Western blot, respectively. It was found that high‐molecular water‐soluble substances (HWSS) significantly increased the expression of cytokines (cyclooxygenase‐2 (COX‐2), inducible nitric oxide synthase (iNOS), and interleukin 6 (IL‐6)) and cyclooxygenase 2 (COX‐2) protein; gel filtration chromatography fraction 1 (GFC‐F1) further purified from HWSS showed prominent pro‐inflammatory effects by increasing the transcription of cytokines (COX‐2, iNOS, tumor necrosis factor alpha (TNF‐α), and interleukin 1β (IL‐1β)) as well as the expression of COX‐2 and iNOS protein. Moreover, GFC‐F1 activated nuclear factor‐kappa B (NF‐кB) (p65 and inhibitor of nuclear factor‐kappa B alpha (IκB‐α)) and the p38/MAPK (mitogen‐activated protein kinase) signaling pathways. On the other hand, the inhibitor of the NF‐κB pathway (pyrrolidine dithiocarbamate (PDTC)) reduced GFC‐F1‐induced nitric oxide (NO) production, while the inhibitors of the MAPK pathways did not. Taken together, GFC‐F1 is the potential composition that caused GAS through the production of inflammatory cytokines by activating the NF‐кB pathway.
Robotic lateral oropharyngectomy following diagnostic tonsillectomy is oncologically safe in patients with human papillomavirus‐related squamous cell cancer: Long‐term results
Authors: Siddiq Somiah , Stephen Sarah , Lin Daniel , Fox Hannah , Robinson Max , Paleri Vinidh 
Published: September 2022

AbstractIntroductionTo report the long‐term oncological and functional outcomes of en bloc TORS lateral oropharyngectomy to address the close/involved margin following diagnostic tonsillectomy in HPV‐related SCC of unknown primary.Material and methodsA single tertiary center observational cohort over a 4‐year period. Primary outcome measures were disease‐specific survival (DSS), overall survival (OS), and PSS NOD (Performance Status Scale‐Normalcy of Diet) scores.ResultsTORS specimens did not evidence residual carcinoma in 93% of patients. Of 14 patients, 50% received surgery alone (median follow‐up 57 months; range 46–96), the remainder surgery and adjuvant therapy (median follow‐up of 58 months; range 51–69) with 100% DSS, OS and no deterioration of PSS NOD scores.ConclusionsLong‐term oncological outcomes confirm TORS lateral oropharyngectomy alone is an oncologically safe treatment. Due consideration of this approach is warranted to mitigate against the morbidity of adjuvant radiotherapy treatment in this group of patients.
Hysteresis in streamflow‐water table relation provides a new classification system of rainfall‐runoff events
Authors: Gelmini Ylenia , Zuecco Giulia , Zaramella Mattia , Penna Daniele , Borga Marco 
Published: September 2022

AbstractRainfall‐runoff event types can be used to better understand the hydrological functioning of catchments. In this study, we propose a framework to characterize and classify runoff events relying on the hysteresis analysis of the relation between streamflow (independent variable) and depth to water table (dependent variable). We evaluated hysteresis for 112 rainfall‐runoff events occurred in the period 2012–2016 in a small forested catchment in the Italian Pre‐Alps. Three main groups of rainfall‐runoff events were identified, each associated with specific hydro‐meteorological characteristics of the events. A first group, identified by a faster response of streamflow compared to the groundwater level (which led to a clockwise hysteretic loop), was characterized by dry antecedent conditions, short rainfall events, low streamflow peaks and small runoff coefficients. A second group had characteristics similar to the first group, that is, faster response of streamflow compared to the groundwater level (clockwise hysteretic loop), but on average displayed a narrower hysteretic loop. A third group, identified by a faster response of the groundwater level compared to streamflow (which led to an anti‐clockwise loop), was characterized by wet antecedent conditions, long rainfall events, high streamflow peaks and large runoff coefficients. Results showed statistically significant differences among the groups, corroborated by an analysis based on environmental tracers (2H and electrical conductivity). This study shows how the analysis of the hysteretic relation between streamflow and depth to water table can be used for grouping rainfall‐runoff events and to better identify the catchment's hydrological response to rainfall inputs.
What is an insolvency proceeding? Gategroup lands in a gated community
Authors: Mokal Riz 
Published: September 2022

AbstractMany English (and other) restructuring lawyers consider that the scheme of arrangement cannot properly be characterized as an insolvency proceeding for the purposes of certain international instruments for (amongst other things) the allocation of jurisdiction and/or the recognition of proceedings, judgments, and/or orders. This article shows that this view is mistaken. The article examines insolvency as a scalar attribute and a vague concept. It draws out the implications of treating insolvency law functionally as that part of law which responds to the circumstances peculiar to a debtor's insolvency. It considers the nature of insolvency, “pre‐insolvency”, “preventive'”, restructuring, liquidation, and “pre‐pack” proceedings. It shows that proceedings operating under insolvency law in relation to insolvent debtors often operate in identical or materially similar ways in relation to solvent debtors. This is as true of winding‐up, administration, and company voluntary arrangement proceedings under English law as of the scheme of arrangement. This has important implications for the characterization of a proceeding as an insolvency proceeding for relevant purposes. The article outlines the development of the concordat in several civil law jurisdictions, starting with its roots in Justinian's Digest. It traces the development of the composition in England, starting with its status as a voluntary process incapable of binding dissentients, taking in the “protections” granted by the Privy Council and the “bills of conformity” issued by the Court of Chancery, and then considering statutory compositions. It shows how the statutory composition travelled from natural person insolvency law to corporate insolvency law. The artic draws on this analysis and the official reports on key European instruments allocating international jurisdiction in insolvency and “civil and commercial” matters to characterise the scheme of arrangement. The article also assesses the most detailed critique yet of the gategroup judgment of the High Court of England and Wales, which characterized the restructuring plan proceeding as an insolvency proceeding for certain jurisdictional purposes. The critique of this judgment usefully exposes to the sunlight of public scrutiny — at length and independently of the exigencies of any particular litigation — the types of arguments which have been used to resist the conclusion that the scheme is (quite plainly) a judicial composition which constitutes an insolvency proceeding for relevant purposes when deployed in relation to insolvent companies. The article shows that these arguments are unpersuasive.
Minimum wages and restaurant employment for teens and adults in metropolitan and nonmetropolitan areas
Authors: Winters John V. 
Published: September 2022

AbstractThis study estimates effects of minimum wages on individual restaurant employment using the 2005–2019 Current Population Survey (CPS) and a two‐way fixed effects regression model. I examine effects for teens and adults with less than an associate's degree for the entire United States and by metropolitan area status. The results indicate that minimum wages on average decrease restaurant employment for teens and increase restaurant employment for these adults, suggesting that minimum wages induce labor‐labor substitution. However, this pattern is driven by metropolitan areas residents. The estimated coefficient for minimum wages on teen restaurant employment in nonmetropolitan areas is not statistically significant.