bluuebunny/crossref_metadata_2025_split huggingface dataset:
The incidence of thyroid dysfunction in diabetic patients – A study done at a tertiary care center in South India
Authors: Sam Sancy Mary , Stephen Sethu 
Published: January 2022

It has been noted that in the Indian population the incidence of thyroid disorder is common and its incidence rises with advancing age. Screening for thyroid disorder is indicated for the certain high risk patients such as elderly and those already having other endocrinal disorders There are various studies that have shown a finding that a higher than normal prevalence of thyroid disorders in type 2 diabetic patients, of which hypothyroidism is the commonest disorder Owing to this we at the medical college at south India decided to evaluate the occurrence of thyroid dysfunction in patients who have been diagnosed with diabetes mellitus and also to compare the level of thyroid dysfunction in the younger and the older population.Department of surgery, medicine and Pharmacology at Al Azhar Medical College Thodupuzha, Kerala, India for a duration of 3 years on 300 patients. The present study was an observational study during the period of study, the test subjects patients having diabetes mellitus and healthy individuals (Controls)coming for regular health check-up with no co morbidities detected were included in this study as controls.In the non -geriatric age group the mean age was 49.6 years SD + 8.15 years and in the geriatric age group the mean age was 68.78 years SD + 4.83 years. The commonest age group in the study was between the age of 61-70 years with of the study population. The age group in the present study ranged between the age of 30 years and 79 years. The incidence of diabetes mellitus increased with age, but the control of sugars is better with age thyroid dysfunction was as follows 20% had hyperthyroidism (36%) hypothyroidism. There is a linear increase with the prevalence of thyroid disorders with age with a r= 0.77 and p &#60; 0.05.The incidence of thyroid dysfunction also increased with age As compared to the non -geriatric group which was the incidence higher in older age group p &#60; 0.05.This study reveals about at least one in three who have DM are suffering from thyroid dysfunction, that increases with increasing age and uncontrolled sugars in this part of the world, which might warrant routine screening.
Post-Covid tracheal resection – first case in India
Authors: Choudhary Anjoo A. , Ezzy Kamruddin K. , Jadhav Supriya V. 
Published: January 2022

Prolonged intubations result in tracheal damage and stenosis, the treatment for severe cases is resection and anastomosis. With the progress of the Covid-19 pandemic, this incidence kept rising but the timing and precautions for such aerosolising surgeries remained unclear. To report the first case of tracheal resection and anastomosis in India done during the Covid-19 pandemic along with its rationale. We report a case of 30/male with prolonged intubation and tracheostomy done for Covid-19 pneumonia and ARDS with failure to decannulate and complete loss of voice. After thorough preoperative work-up, he underwent tracheal resection of 4 rings with cricotracheal anastomosis during the covid-19 pandemic in October 2020. He was extubated on table and was asymptomatic after 3 months of follow-up with excellent voice. With good team effort and appropriate precautions, aerosolising airway surgeries resection anastomosis can be safely performed.
Intracranial pilocytic astrocytoma with spinal drop metastasis: A case review, discussion of its current management and related literature
Authors: Keshri Shekhar Kumar , Sinha Satyendra Narayan 
Published: January 2022

Pilocytic astrocytoma (PA) is a low grade benign tumor, commonly occurs in Cerebellum (42-60%), Optic & hypothalamic region (9-30%), Brain Stem (9%). They rarely spread. It rarely occurs within the ventricle. In this report, we described our experience with cranial pilocytic astrocytoma in a 14-year-old child, who initially treated with near total decompression of tumor. Four and half years later, recurrence of primary tumor with obstructive hydrocephalus occurred for which he underwent ventriculo-peritoneal shunt followed by re-excision. As further treatment was being evaluated for radiotherapy in view of recurrence at the primary site, he got detected to have significant spinal drop metastasis seen on MRI Spine. Finally, he underwent craniospinal irradiation (CSI).
Correlates of COVID-19 vaccination drop-out among health care workers in a tertiary Care hospital of West Bengal
Authors: Basu Mausumi , Saha Ripan , Basu Subhra Samujjwal , Shukla Vineeta , Mishra Ankita , Mukherjee Meghna 
Published: January 2022

The Government of India launched “COVID-19 vaccination drive” on 16th January, 2021 and health care workers were the first to be prioritised for vaccination. However, the uncertainty regarding safety and efficacy of the vaccine was the major concern amongst them. These led to vaccine hesitancy and ultimately drop out.To estimate the proportion of drop out of COVID-19 vaccination among vaccine-hesitant health care workers (HCWs) of a tertiary care hospital and to find out their perception and other background characteristics responsible for drop out. A facility based descriptive type of observational study, cross-sectional in design was carried out among 329 HCWs of a tertiary care hospital in Kolkata from 16th March- 12thApril, 2021using a pre-designed, pre-tested, structured questionnaire. The study population selected by simple random sampling technique. Data was analysed using Microsoft Excel 2010 and SPSS v25.0 in the form of descriptive statistics and binary logistic regression. About 44.1% of the study population didn’t take the COVID-19 vaccine. Socio-demographic factors like age, gender, religion, education, occupation,perception regarding necessity of vaccination, vaccine efficacy, dose and contraindication, safety in humans and role in future infections were significantly associated with drop out. There was a high proportion of vaccine drop out among health care workers. Different modifiable perceptions with socio-demographic factors had played important roles in COVID-19 vaccination drop out. As the global threat of COVID-19 continues, greater efforts through campaigns that target HCWs are needed to improve the intention of professionals’ vaccine acceptance.
Management of menstrual hygiene, practices and perceptions among vulnerable Bharia women in Madhya Pradesh: A pilot survey
Authors: Kumar Dinesh , Vaiyam Poonam , Thakur Ravikanta Singh 
Published: January 2022

India has the highest proportion of adolescents and the highest adolescent pregnancy and childbirth rate in the tribal segment of the population. Very few studies have focused on the use of sanitary pad and quality of health care as menstrual hygiene practices.The data was collected among ‘Bharia’ women who identified as one of the particularly vulnerable tribal groups (PVTGs) in Madhya Pradesh. Towards comparing the use, source, and components of menstrual hygiene practices among adolescents and adult mothers, the sample included adolescent (10-19 years) and adult women 20-49 years of age. The relevant information was collected by trained female investigator with designed questionnaire from the respondents.Findings revealed that only 22.7% women are using sanitary pad during menstruation period in the studied tribe. It was seen the use of this absorbent (sanitary pad) for menstrual hygiene among the adolescents were found significantly higher (37.5%) than that of adult women (14.3%), whereas, the use of old cotton was found significantly higher (78.6%) among adult women. Awareness on menstrual hygiene about 50% adolescents and 64% adult women believed it is a curse of God. About 25% adolescents and 21.4% adult women believed menstruation is a natural process.The tribe has underprivileged menstrual hygiene practices owing to low awareness, illiteracy, and poverty. The special IEC education campaign with suitable strategy can be forced to optimum hygiene practices.
Study of COVID-19 impact on teaching community in border area of India
Authors: Mahajan Vishal , Mahajan Shailly 
Published: January 2022

The COVID-19 pandemic has made the biggest disturbance of education frameworks in mankind's set of experiences, influencing almost 1.6 billion students in excess of 200 nations. Terminations of schools, Colleges and other learning institutions have affected over 94% of the world's understudy populace. This has brought sweeping changes in all parts of our lives. Social separating and prohibitive development strategies have fundamentally upset conventional instructive practices. Returning of schools after unwinding of limitation is one more test with numerous new standard working methodology set up. Inside a limited ability to focus the COVID-19 pandemic, numerous scientists have shared their chips away at educating and learning in an unexpected way. A few schools, universities and colleges have stopped up close and personal lessons. There is a dread of losing 2020 scholastic year or considerably more in the coming future. The need of great importance is to enhance and carry out elective instructive framework and appraisal procedures. The COVID-19 pandemic has furnished us with a chance to make ready for presenting advanced learning. This article expects to give an exhaustive report on the effect of the COVID-19 pandemic on internet educating and learning of different papers and show the way forward.
Outcomes in patients of pulmonary tuberculosis treated under RNTCP & follow up after 6 months
Authors: Gupta Sonisha , Porwal Ankur , Gupta Atul Kumar 
Published: January 2022

Tuberculosis (TB) is, one of the top 10 causes of death worldwide and the leading cause of death from a single infectious agent.This Prospective study was conducted at Santosh medical college Ghaziabad from 1 April 2018 to 30 September 2019. All diagnosed PTB patients above 12yrs were taken. Patients with EPTB, HIV positive, MDR TB, XDR TB were excluded from the study. At the end of study treatment outcome was evaluated.Total of 208 patients diagnosed as tuberculosis were enrolled in the study. 6 patients died during course of study, 10 were treatment failure, 4 were lost to follow-up, 3 transferred out & 1 shifted to private treatment. 184 patients completed treatment successfully. Out of 184, only 152 patients were available for interview at 6 months follow up after completion of treatment. 19 could not be traced, 11 patients refused and 2 died. Out of 152, 110 were asymptomatic, 1 relapsed & rest 41 patients were symptomatic. All symptomatic patients were subjected to Chest X-Ray. Fibrosis was seen on CXR of 30 patients, bronchiectasis was seen in 3 patients, 1 patient had destroyed lung, nothing abnormal detected in 7 patients.Even after successful treatment under RNTCP, these patients need to be followed up as many of them relapse or suffer from sequelae of tuberculosis.
Application of Artificial Intelligence in Chemistry
Authors: Rai Preeti , Chatrath Harsha 
Published: January 2022

All the problems can be solved with the help of machines mainly computers using algorithm and by interpreting their output data is considered as artificial intelligence (AI). Artificial intelligence is faster than manual work, reduces manpower, more efficient and accurate and used in various field these days and coming up with more advanced technology. With the help of artificial intelligence, drugs can be formulated and produced in an advanced way. New machineries’ used in chemical or pharmaceutical labs are much advanced these days, that reduces the time of the analysis.
There is a strong bond between artificial intelligence and chemistry. In the field of chemistry designing new molecules, molecular property detection of molecules and compounds, drug discovery, synthesis and retrosynthesis of molecules, analysis prediction for better and accurate results, all these can be done with the help of artificial intelligence.
Ideas in Context: a Conversation with Frank Cunningham
Authors: Coburn Elaine , Cunningham Frank , Glasbeek Harry , Holden Meg , Mills Charles , Rein Sandra 
Published: January 2022

Moderated by Elaine Coburn, Harry Glasbeek, Meg Holden, Charles Mills and Frank Cunningham presented a symposium on Frank's book Ideas in Context May 29, 2021 for the Society of Socialist Studies. Now shared here in written form, the symposium includes what may have been the last contribution of Charles Mills, a friend of half of a century to Frank, known for his generosity of spirit and his trenchant theorizing of racial justice (Mills 1997).
Effects of Water Temperature on Activities of Metabolic Enzymes of Juvenile Siganus guttatus
Authors: Song C. , Wang Y. , Liu J.Y. , Zhao F. , Huang X.R. , Zhuang P. 
Published: January 2022

Background: Temperature is one of the most important environmental factors affecting the survival, growth and metabolism of fish. The current study was aimed to study the effects of water temperature on the metabolic enzyme activities of juvenile Siganus guttatus. Methods: The juveniles were domesticated at 28±1°C for two weeks and then the temperature was adjusted to the target temperature groups (31°C, 27°C, 23°C and 19°C) by the gradually increasing or decreasing temperature with the change rate of 2°C per day. The experiment lasted for 70 d. At the end of the experiment, the fish were anesthetized and all the livers were dissected on ice plate and stored in the refrigerator at -80°C for the determination of enzyme activity. Result: The activities of glutamic pyruvic transaminase (GPT) and glutamic oxaloacetic transaminase (GOT), hexokinase (HK) and pyruvate kinase (PK), lipoprotein lipase (LPL) and hepatic lipase (HL) tend to be increased with the reduction of temperature. The above enzymes activities in 19°C group were highest. The activity of lactate dehydrogenase (LDH), succinate dehydrogenase (SDH) and citrate synthase (CS) was lowest in 19°C. These results suggests that 19°C had exceeded the suitable temperature range for juvenile S. guttatus. At low temperature, S. guttatus mainly use fat for energy, but less anaerobic metabolism for energy.
Potential of Sambiloto (Andrographis paniculata Nees) Extract against Salmonella Pullorum
Authors: Hidanah Sri , Sabdoningrum Emy Koestanti , . Soeharsono , Andira Ayu , Varhana Noor Amina 
Published: January 2022

Background: Salmonella Pullorum are pathogenic bacteria that causes salmonellosis and causes heavy economic losses in the poultry industry and are zoonotic. Treatment of diseases caused by bacteria generally use antibiotics, but excessive administration of antibiotics causes bacterial resistance and residues in livestock. Major chemical constituents of Sambiloto are andrographolide and flavonoids. Andrographolide has antibacterial effect in addition to being antitoxic, anticancer, anti-inflammatory and antiallergic.
Methods: The research was conducted by isolating and identifying Salmonella Pullorum on SSA media and a series of biochemical tests (TSIA, SIM, SCA, urea media and sugar test), manufacturing sambiloto extract, testing the sensitivity of several antibiotics using the disk diffusion method and testing the activation of sambiloto extract against Salmonella Pullorum using the disk diffusion and dilution methods. Result: The result show that sambiloto had antibacterial activity because it contained andrographolide, flavonoids, saponins, alkaloids and tannins and the lowest extract dose that effectively killed Salmonella Pullorum is concentrations of 20%.
Cultural Landscapes Preservation at the Interface of Urban Planning and Sprawl
Authors: Imene Laouar 
Published: January 2022

From ancient times, the sea has played a key role in shaping and generating settlements and cities. The history of civilizations has been marked by the cultural development of human societies along coastlines. Accordingly, these territories are harbor of an important coastal heritage; that plays a pivotal role in maintaining the link between the past and the future. In fact, while cities grow and their populations increase, their planning becomes a challenge for sustainable development. Through different forms and mechanisms, coastal sprawl is materialized, by the massive occupation of populations and industrial activities along coastlines. In this vein, coastlines endure many conflicts, which lead to the degradation of cultural and natural resources and may result in loss of cultural identity associated with the presence of cultural landscapes. The paper aims, to discuss planning approaches and challenges related to managing cultural and coastal landscapes, facing the impact of coastal sprawl. The paper is based on a landscape analysis; it interviews the urban, social, juridical and morphological frame. An understanding of urban sprawl through the lens of Annaba’s coastline is required for its implication as a social support of the identity and the history of the city. The paper also examines how the coastalization affects the cultural heritage based on the monograph of one of the valuable French colonial constructions in Algeria. Lastly, the study demonstrates, some key opportunities for advancing future adjustments, and coastal management approaches. For instance, new tools and more appropriate methodologies that combine the preservation of the coastline and the preservation of the cultural heritage.
Towards Programs Sustainability: Assessment of Institutional Determinants for Effective Community Participation in Development Programs in Tanzania
Authors: Naku Daniel Wandera Clief , Kihila Jacob , Mwageni Eluether 
Published: January 2022

This paper brings to the fore an assessment of institutional determinants for effective community participation in development programs for the case of Tanzania. It is highly acknowledged in various scholarly literature that there is a strong link between community participation and development programs. In fact, literature shows that community-based development programs that have allowed community members to be fully involved in various programs have been successful when compared to those where community members are seen as spectators.However, in order for community members to take part in the programs, there are several determining factors, ranging from socio-economic, socio-cultural to institutional based factors.This study therefore sought to assess institutional determinants with the aim of identifying the major institutional determinants capable of influencing effective community participation in development programs. The study used four programs that were categorized as Locally Funded, Government Funded, Donor Funded and Joint Funded development programs. A combined sample size of 316 participants from all the four programs was employed. Collected data were analyzed through the within-case analysis and the comparative analysis approaches.Results of the study revealed that program benefits, objectives and leadership were the major institutional determinants for promoting effective community participation in development programs. when compared to methods used in the other three examined programs. Hence, the study concluded by emphasizing on the need to ensure these institutional based factors (program benefits, objectives and leadership) should always be given due attention in any development program.
Challenges facing components reuse in industrialized housing: A literature review
Authors: Margherita Lisco , Carlos Martinez , Urban Persson 
Published: January 2022

Concerns over the earth’s ability to sustain itself over the long term as a consequence of human consumption of natural resources points towards sustainable development. Since a large proportion of human consumption is linked to buildings and construction, this means managing the construction process in more sustainable ways. Strategies that target greater material efficiency and which promote circular economy concepts are among several approaches that are gaining in popularity. The adoption of life-cycle thinking and practices in design, construction and end of life through the reuse of construction components and materials is one such action to achieve a sustainable built environment. Reuse is not a new concept and technical solutions do exist; however, practical realization is hampered by many interrelated challenges. This review paper is the result of a literature review for an exploratory study that aims to identify obstacles to the reuse of building components and materials. The context is industrialized housing, particularly timber-based construction, as this is a sector where modern manufacturing and onsite practices have become established. The main obstacles identified and corroborated in the literature, along with their potential solutions, are summarized and conclusions drawn on the future direction of research needs.
Using a Convolutional Neural Network and Convolutional Long Short-term Memory to Automatically Detect Aneurysms on 2D Digital Subtraction Angiography Images: Framework Development and Validation
Authors: Liao JunHua , Liu LunXin , Duan HaiHan , Huang YunZhi , Zhou LiangXue , Chen LiangYin , Wang ChaoHua 
Published: January 2022

Background
It is hard to distinguish cerebral aneurysms from overlapping vessels in 2D digital subtraction angiography (DSA) images due to these images’ lack of spatial information.

Objective
The aims of this study were to (1) construct a deep learning diagnostic system to improve the ability to detect posterior communicating artery aneurysms on 2D DSA images and (2) validate the efficiency of the deep learning diagnostic system in 2D DSA aneurysm detection.

Methods
We proposed a 2-stage detection system. First, we established the region localization stage to automatically locate specific detection regions of raw 2D DSA sequences. Second, in the intracranial aneurysm detection stage, we constructed a bi-input+RetinaNet+convolutional long short-term memory (C-LSTM) framework to compare its performance for aneurysm detection with that of 3 existing frameworks. Each of the frameworks had a 5-fold cross-validation scheme. The receiver operating characteristic curve, the area under the curve (AUC) value, mean average precision, sensitivity, specificity, and accuracy were used to assess the abilities of different frameworks.

Results
A total of 255 patients with posterior communicating artery aneurysms and 20 patients without aneurysms were included in this study. The best AUC values of the RetinaNet, RetinaNet+C-LSTM, bi-input+RetinaNet, and bi-input+RetinaNet+C-LSTM frameworks were 0.95, 0.96, 0.92, and 0.97, respectively. The mean sensitivities of the RetinaNet, RetinaNet+C-LSTM, bi-input+RetinaNet, and bi-input+RetinaNet+C-LSTM frameworks and human experts were 89% (range 67.02%-98.43%), 88% (range 65.76%-98.06%), 87% (range 64.53%-97.66%), 89% (range 67.02%-98.43%), and 90% (range 68.30%-98.77%), respectively. The mean specificities of the RetinaNet, RetinaNet+C-LSTM, bi-input+RetinaNet, and bi-input+RetinaNet+C-LSTM frameworks and human experts were 80% (range 56.34%-94.27%), 89% (range 67.02%-98.43%), 86% (range 63.31%-97.24%), 93% (range 72.30%-99.56%), and 90% (range 68.30%-98.77%), respectively. The mean accuracies of the RetinaNet, RetinaNet+C-LSTM, bi-input+RetinaNet, and bi-input+RetinaNet+C-LSTM frameworks and human experts were 84.50% (range 69.57%-93.97%), 88.50% (range 74.44%-96.39%), 86.50% (range 71.97%-95.22%), 91% (range 77.63%-97.72%), and 90% (range 76.34%-97.21%), respectively.

Conclusions
According to our results, more spatial and temporal information can help improve the performance of the frameworks. Therefore, the bi-input+RetinaNet+C-LSTM framework had the best performance when compared to that of the other frameworks. Our study demonstrates that our system can assist physicians in detecting intracranial aneurysms on 2D DSA images.