bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH CORPORATE SOCIAL RESPONSIBILITY TERHADAP CORPORATE IMAGE DI KSPPS BMT NU JAWA TIMUR CABANG PAKONG
Authors: Qurratul Aini  , Farid Firmansyah  , Fahrurrozi  
Published: September 2022

Corporate Sosial Responsibility dapat di gunakan sebagai alat marketing baru bagi perusahaan bila itu di laksanakan berkelanjutan. Penelitian ini menggunakan pendekatan kuantitatif dengan teknik analisis regresi linier sedehana. Jenis dalam penelitian ini adalah data primer yang diperoleh melalui kuisioner. Respondennya adalah nasabah dari KSPP BMT NU Cabang Pakong.
Dari hasil penelitian menunjukkan bahwa terdapat pengaruh penerapan Corporate Sosial Responsibilty terhadap Corporate Image di KSPP BMT NU Cabang Pakong Hal tersebut dapat dinyatakan berdasarkan hasil uji-t menghasilkan nilai koefisien korelasi t hitung = 9,749> t tabel = 1,660 dengan taraf signifikan sisebesar 0,000 < 0,05, serta nilai koefisien beta yang bernilai positif. Dari hasil koefisien determinasi (R2) dengan menggunakan SPSS (Statistical for The Social Sciences) versi24, dengan melihat perolehan R square sebesar 0,419. Artinya 41,9% Corporate Image dijelaskan melalui Corporate Sosial Responsibilty di KSPP BMT NU Cabang Pakong. Dari persamaan regresi linier sederhana (Y = a+ bX) yaitu Y = 6,222 + 0,536X, dimana nilai konstanta (a) Corporate Image sebesar 6,222 menunjukkan bahwa jika variable Corporate Sosial Responsibilty sama dengan nol (tidak dipertimbangkan), maka Corporate Image adalah sebesar 6,222 satuan dan b = 0,536, dapat diartikan bahwa besarnya koefisien variabel Corporate Image bertanda positif (0,536) mengindikasikan bahwa jika Corporate Sosial Responsibilty naik 1 satuan, maka skor Corporate Image akan naik sebesar 0,536 satuan.
Analisis Manajemen Unit Usaha Pesantren Ma’had Darut Tauhid (Madad) Di Desa Rapa Laok Kecamatan Omben Kabupaten Sampang
Authors: Pratama Angga , Qamariyah Siti 
Published: September 2022

Rendahnya pemahaman dan penerapan manajemen Unit Usaha Pesantren, berakibat terhadap penghasilan dan kemajuan Pesantren Ma’had Darut Tauhid (MADAD) yang berdampak pada kelangsungan perekonomian Pesantren. Maka untuk mengetahui seberapa besar penerapan manajemen yang dilaksanakan, perlu dilakukannya penelitian. Penelitian ini menggunakan metode diskriptif kualitatif.
Hasilnya, banyak para petugas Unit Usaha Pesantren yang masih belum mengetahui sistem manajemen. Sehingga perlu dibekali pelatihan secara terus menerus, guna meningkatkan kualitas kerja dan memberikan manfaat bagi unit usaha pesantren Ma’had Darut Tauhid (MADAD) khususnya didalam bidang manajemen dengan harapan besar jika pengelolaan manajemennya dilaksanakan dengan benar dan tepat maka dapat meningkatkan pendapatan dan kesejahteraan pesantren sekaligus semua aspek yang berkaitan dengan pesantren.
The effect of calcium supplementation in people under 35 years old: A systematic review and meta-analysis of randomized controlled trials
Authors: Liu Yupeng , Le Siyu , Liu Yi , Jiang Huinan , Ruan Binye , Huang Yufeng , Ao Xuemei , Shi Xudong , Fu Xiaoyi , Wang Shuran 
Published: September 2022

Background:The effect of calcium supplementation on bone mineral accretion in people under 35 years old is inconclusive. To comprehensively summarize the evidence for the effect of calcium supplementation on bone mineral accretion in young populations (≤35 years).Methods:This is a systematic review and meta-analysis. The Pubmed, Embase, ProQuest, CENTRAL, WHO Global Index Medicus, Clinical Trials.gov, WHO ICTRP, China National Knowledge Infrastructure (CNKI), and Wanfang Data databases were systematically searched from database inception to April 25, 2021. Randomized clinical trials assessing the effects of calcium supplementation on bone mineral density (BMD) or bone mineral content (BMC) in people under 35 years old.Results:This systematic review and meta-analysis identified 43 studies involving 7,382 subjects. Moderate certainty of evidence showed that calcium supplementation was associated with the accretion of BMD and BMC, especially on femoral neck (standardized mean difference [SMD] 0.627, 95% confidence interval [CI] 0.338–0.915; SMD 0.364, 95% CI 0.134–0.595; respectively) and total body (SMD 0.330, 95% CI 0.163–0.496; SMD 0.149, 95% CI 0.006–0.291), also with a slight improvement effect on lumbar spine BMC (SMD 0.163, 95% CI 0.008–0.317), no effects on total hip BMD and BMC and lumbar spine BMD were observed. Very interestingly, subgroup analyses suggested that the improvement of bone at femoral neck was more pronounced in the peripeak bone mass (PBM) population (20–35 years) than the pre-PBM population (<20 years).Conclusions:Our findings provided novel insights and evidence in calcium supplementation, which showed that calcium supplementation significantly improves bone mass, implying that preventive calcium supplementation before or around achieving PBM may be a shift in the window of intervention for osteoporosis.Funding:This work was supported by Wenzhou Medical University grant [89219029].
Nitrate enrichment does not affect enteropathogenic Escherichia coli in aquatic microcosms but may affect other strains present in aquatic habitats
Authors: Davis Meredith T. , Canning Adam D. , Midwinter Anne C. , Death Russell G. 
Published: September 2022

Eutrophication of the planet’s aquatic systems is increasing at an unprecedented rate. In freshwater systems, nitrate—one of the nutrients responsible for eutrophication—is linked to biodiversity losses and ecosystem degradation. One of the main sources of freshwater nitrate pollution in New Zealand is agriculture. New Zealand’s pastoral farming system relies heavily on the application of chemical fertilisers. These fertilisers in combination with animal urine, also high in nitrogen, result in high rates of nitrogen leaching into adjacent aquatic systems. In addition to nitrogen, livestock waste commonly carries human and animal enteropathogenic bacteria, many of which can survive in freshwater environments. Two strains of enteropathogenic bacteria found in New Zealand cattle, are K99 and Shiga-toxin producing Escherichia coli (STEC). To better understand the effects of ambient nitrate concentrations in the water column on environmental enteropathogenic bacteria survival, a microcosm experiment with three nitrate-nitrogen concentrations (0, 1, and 3 mg NO3-N /L), two enteropathogenic bacterial strains (STEC O26—human, and K99—animal), and two water types (sterile and containing natural microbiota) was run. Both STEC O26 and K99 reached 500 CFU/10 ml in both water types at all three nitrate concentrations within 24 hours and remained at those levels for the full 91 days of the experiment. Although enteropathogenic strains showed no response to water column nitrate concentrations, the survival of background Escherichia coli, imported as part of the in-stream microbiota did, surviving longer in 1 and 3 mg NO3-N/Lconcentrations (P < 0.001). While further work is needed to fully understand how nitrate enrichment and in-stream microbiota may affect the viability of human and animal pathogens in freshwater systems, it is clear that these two New Zealand strains of STEC O26 and K99 can persist in river water for extended periods alongside some natural microbiota.
Screening for Syphilis Infection in Nonpregnant Adolescents and Adults
Authors:   US Preventive Services Task Force, Mangione Carol M. , Barry Michael J. , Nicholson Wanda K. , Cabana Michael , Chelmow David , Coker Tumaini Rucker , Davis Esa M. , Donahue Katrina E. , Jaén Carlos Roberto , Kubik Martha , Li Li , Ogedegbe Gbenga , Pbert Lori , Ruiz John M. , Stevermer James , Wong John B. 
Published: September 2022

ImportanceSyphilis is a sexually transmitted infection that can progress through different stages (primary, secondary, latent, and tertiary) and cause serious health problems if left untreated. Reported cases of primary and secondary syphilis in the US increased from a record low of 2.1 cases per 100 000 population in 2000 and 2001 to 11.9 cases per 100 000 population in 2019. Men account for the majority of cases (83% of primary and secondary syphilis cases in 2019), and rates among women nearly tripled from 2015 to 2019.ObjectiveTo reaffirm its 2016 recommendation, the US Preventive Services Task Force (USPSTF) commissioned a reaffirmation evidence update focusing on targeted key questions evaluating the performance of risk assessment tools and the benefits and harms of screening for syphilis in nonpregnant adolescents and adults.PopulationAsymptomatic, nonpregnant adolescents and adults who have ever been sexually active and are at increased risk for syphilis infection.Evidence AssessmentUsing a reaffirmation process, the USPSTF concludes with high certainty that there is a substantial net benefit of screening for syphilis infection in nonpregnant persons who are at increased risk for infection.RecommendationThe USPSTF recommends screening for syphilis infection in persons who are at increased risk for infection. (A recommendation)
Association of SARS-CoV-2 Seropositivity With Myalgic Encephalomyelitis and/or Chronic Fatigue Syndrome Among Children and Adolescents in Germany
Authors: Sorg Anna-Lisa , Becht Selina , Jank Marietta , Armann Jakob , von Both Ulrich , Hufnagel Markus , Lander Fabian , Liese Johannes G. , Niehues Tim , Verjans Eva , Wetzke Martin , Stojanov Silvia , Behrends Uta , Drosten Christian , Schroten Horst , von Kries Rüdiger 
Published: September 2022

ImportanceDuring the COVID-19 pandemic, a reduction in quality of life and physical and mental health among children and adolescents has been reported that may be associated with SARS-CoV-2 infection and/or containment measures.ObjectiveTo assess the association of SARS-CoV-2 seropositivity with symptoms that may be related to myalgic encephalomyelitis and/or chronic fatigue syndrome (ME/CFS) among children and adolescents.Design, Setting, and ParticipantsThis substudy of the cross-sectional SARS-CoV-2 seroprevalence surveys in Germany (SARS-CoV-2 KIDS) was performed in 9 pediatric hospitals from May 1 to October 31, 2021. Pediatric patients were recruited during an inpatient or outpatient visit regardless of the purpose of the visit. Parental questionnaires and serum samples were collected during clinically indicated blood draws. The parental questionnaire on demographic and clinical information was extended by items according to the DePaul Symptom Questionnaire, a pediatric screening tool for ME/CFS in epidemiological studies in patients aged 5 to 17 years.ExposuresSeropositivity was determined by SARS-CoV-2 IgG antibodies in serum samples using enzyme-linked immunosorbent assays.Main Outcomes and MeasuresKey symptoms of ME/CFS were evaluated separately or as clustered ME/CFS symptoms according to the DePaul Symptom Questionnaire, including fatigue.ResultsAmong 634 participants (294 male [46.4%] and 340 female [53.6%]; median age, 11.5 [IQR, 8-14] years), 198 (31.2%) reported clustered ME/CFS symptoms, including 40 of 100 SARS-CoV-2–seropositive (40.0%) and 158 of 534 SARS-CoV-2–seronegative (29.6%) children and adolescents. After adjustment for sex, age group, and preexisting disease, the risk ratio for reporting clustered ME/CFS symptoms decreased from 1.35 (95% CI, 1.03-1.78) to 1.18 (95% CI, 0.90-1.53) and for substantial fatigue from 2.45 (95% CI, 1.24-4.84) to 2.08 (95% CI, 1.05-4.13). Confinement to children and adolescents with unknown previous SARS-CoV-2 infection status (n = 610) yielded lower adjusted risks for all symptoms except joint pain ME/CFS–related symptoms. The adjusted risk ratio was 1.08 (95% CI, 0.80-1.46) for reporting clustered ME/CFS symptoms and 1.43 (95% CI, 0.63-3.23) for fatigue.Conclusions and RelevanceThese findings suggest that the risk of ME/CFS in children and adolescents owing to SARS-CoV-2 infection may be very small. Recall bias may contribute to risk estimates of long COVID-19 symptoms in children. Extensive lockdowns must be considered as an alternative explanation for complex unspecific symptoms during the COVID-19 pandemic.
The characteristics of Laennec's capsule around the hepatic veins: A histological study based on 71 liver surgical specimens
Authors: Zhang Yuanpeng , Shi Ning , Zou Yiping , Zeng Wenrong , Chen Zhihong , Chen Zhenrong , Wu Fan , Jin Haosheng 
Published: September 2022

AbstractBackgroundLaennec's capsule is a fibrous membrane attached to the surface of the liver, which is independent of the hepatic veins. However, the presence of Laennec's capsule surrounding the peripheral hepatic veins is controversial. This study aims to describe the characteristic of Laennec's capsule around the hepatic veins at all levels.MethodsSeventy‐one hepatic surgical specimens were collected along the cross and longitudinal sections of the hepatic vein. Tissue sections of 3–4 mm were cut and stained with hematoxylin and eosin (H&E), resorcinol‐fuchsin (R&F), and Victoria blue (V&B). Elastic fibers were observed around the hepatic veins. They were measured using K‐Viewer software.ResultsMorphologically, we observed a thin, dense fibrous layer (so‐called Laennec's capsule) around the hepatic veins at all levels, which was different from the thick elastic fibers of the hepatic vein wall. Therefore, there was a potential gap between Laennec's capsule and the hepatic veins. Laennec's capsule was visualized significantly better with R&F and V&B staining compared to H&E staining. The thickness of Laennec's capsule around the main, first, and secondary branches of the hepatic vein were 79.86 ± 24.20 μm, 48.41 ± 18.25 μm, and 23.56 ± 10.03 μm in the R&F staining, and 80.15 ± 21.85 μm, 49.46 ± 17.52 μm, and 25.05 ± 11.03 μm in the V&B staining, respectively. They were significantly different from each other (P < .001).ConclusionThe hepatic veins were surrounded by Laennec's capsule at all levels, including the peripheral hepatic veins. However, it is thinner along the vein branches. The gap between the Laennec's capsule and hepatic veins shows potential supplemental value for liver surgery.
Scope of coverage of medical genetics and genomics in pre‐clerkship programs of Canadian faculties of medicine: A curriculum analysis
Authors: Ouellet Jade , Lapointe Julie , Raîche Camille , Guerin Andrea , Helal Shaimaa , Fitzpatrick Jennifer , Dorval Michel , Nabi Hermann 
Published: September 2022

AbstractWe appraised the scope of medical genetics and genomics concepts covered in the pre‐clerkship programs of Canadian faculties of medicine through an analysis of course objectives. All course objectives linked to medical genetics and genomics in pre‐clerkship programs of Canadian faculties of medicine were compiled. From this, the fraction of objectives dedicated to medical genetics and genomics was calculated. Course objectives were also categorized according to a curriculum and a competency classification. Of the 17 Canadian faculties of medicine, the complete set of course syllabi (5 faculties) or the listing of learning objectives (4 faculties) were obtained and reviewed. The fraction of learning objectives dedicated to medical genetics and genomics varied between 0.65% and 5.05%. From the objectives classification, “foundational knowledge” was most frequently covered (64% of the compiled objectives), while topics such as: “ethics and professionalism,” “communicate genetics information,” and “obtain specialist help” were covered by less than 5%. Coverage of medical genetics and genomics in pre‐clerkship programs of Canadian faculties of medicine appears to be low. Genetics and genomics are playing a rapidly expanding role in healthcare and clinical practice and educational programs should consider this new reality.
Pallister‐Hall syndrome, GLI3, and kidney malformation
Authors: McClelland Kathryn , Li Weili , Rosenblum Norman D. 
Published: September 2022

AbstractPallister‐Hall syndrome (PHS) is a rare autosomal dominant disease diagnosed by the presence of hypothalamic hamartoma, mesoaxial polydactyly and a truncating variant in the middle third of the GLI‐Kruppel family member 3 (GLI3) gene. PHS may also include a wide range of clinical phenotypes affecting multiple organ systems including congenital anomalies of the kidney and urinary tract (CAKUT). The observed clinical phenotypes are consistent with the essential role of GLI3, a transcriptional effector in the hedgehog (Hh) signaling pathway, in organogenesis. However, the mechanisms by which truncation of GLI3 in PHS results in such a variety of clinical phenotypes with variable severity, even within the same organ, remain unclear. In this study we focus on presentation of CAKUT in PHS. A systematic analysis of reported PHS patients (n = 78) revealed a prevalence of 26.9% (21/78) of CAKUT. Hypoplasia (± dysplasia) and agenesis were the two main types of CAKUT; bilateral and unilateral CAKUT were reported with equal frequency. Examination of clinical phenotypes with CAKUT revealed a significant association between CAKUT and craniofacial defects, bifid epiglottis and a Disorder of Sex Development, specifically affecting external genitalia. Lastly, we determined that PHS patients with CAKUT predominately had substitution type variants (as opposed to deletion type variants in non‐CAKUT PHS patients) in the middle third of the GLI3 gene. These results provide a foundation for future work aimed at uncovering the molecular mechanisms by which variant GLI3 result in the wide range and severity of clinical features observed in PHS.
Sustainable Wacker‐Type Oxidations
Authors: Rajeshwaran Purushothaman , Trouvé Jonathan , Youssef Khalil , Gramage‐Doria Rafael 
Published: September 2022

AbstractThe Wacker reaction is the oxidation of olefins to ketones and typically requires expensive and scarce palladium catalysts in the presence of an additional copper co‐catalyst under harsh conditions (acidic media, high pressure of air/dioxygen, elevated temperatures). Such a transformation is relevant for industry, as shown by the synthesis of acetaldehyde from ethylene as well as for fine‐chemicals, because of the versatility of a carbonyl group placed at specific positions. In this regard, many contributions have focused on controlling the chemo‐ and regioselectivity of the olefin oxidation by means of well‐defined palladium catalysts under different sets of reaction conditions. However, the development of Wacker‐type processes that avoid the use of palladium catalysts has just emerged in the last few years, thereby paving the way for the generation of more sustainable procedures, including milder reaction conditions and green chemistry technologies. In this Minireview, we discuss the development of new catalytic processes that utilize more benign catalysts and sustainable reaction conditions.
Anion Donicity of Liquid Electrolytes for Lithium Carbon Fluoride Batteries
Authors: Wang Xingxing , Song Ziyu , Wu Hao , Yu Hailong , Feng Wenfang , Armand Michel , Huang Xuejie , Zhou Zhibin , Zhang Heng 
Published: September 2022

AbstractThe increasing demand for high‐energy powers have greatly incentivized the development of lithium carbon fluoride (Li||CFx) cells. Five kinds of non‐aqueous liquid electrolytes with various kinds of lithium salts (LiX, X=PF6−, TFSI−, BF4−, ClO4−, and CF3SO3−) were comparatively studied. Intriguingly, the LiBF4‐based electrolyte show relatively moderate ionic conductivities; yet, the corresponding Li||CFx cells deliver the highest discharge capacities among them. A combination of morphological and compositional analyses of the discharge CFx cathode suggest that the moderate donicity of BF4− anion is accountable for favoring the breakdown of C−F bonds, and subsequently forming crystalline lithium fluoride as the main discharge products. This work brings not only fresh understanding on the role of salt anions for Li||CFx cells, but also inspire the electrolyte design for other conversion‐type (sulfur and/or organosulfur) cathode materials desired for high‐energy applications.
Chromium/Photoredox Dual Catalyzed Synthesis of α‐Benzylic Alcohols, Isochromanones, 1,2‐Oxy Alcohols and 1,2‐Thio Alcohols
Authors: Dutta Subhabrata , Erchinger Johannes E. , Schäfers Felix , Das Ankita , Daniliuc Constantin G. , Glorius Frank 
Published: September 2022

AbstractHerein, a Cr/Photoredox‐catalyzed general synthetic strategy to access α‐benzylic alcohols, isochromanones, oxy alcohols and thio alcohols is unveiled. Alkylation of aldehydes being a crucial C−C bond forming reaction, designing competent catalytic systems would render an attractive and decorated set of diverse alcohol motifs. Considering the challenges associated with classical organometallic chemistry, the strategy of dual catalysis is applied here to generate diverse alcohol motifs in a mild and efficient manner. The amalgamation of photocatalysis with chromium chemistry is chosen for this purpose to generate an environment with low basicity and thus, high chemoselectivity. With alkyl silanes as preferred coupling partners, this catalytic setup produces a broad substrate scope with an excellent functional group tolerance and displays a facile scale‐up as well. Its application towards biologically relevant molecules and product diversification contributes to the synthetic utility of this method.
Structures of the co‐branching reactive products of isotactic polypropylene with high‐density polyethylene and the effect on the in situ compatibilization of mixed recycled materials
Authors: Xu Yinhan , Wang Jun , Luo Zhu , Li Jianjun , Xue Bai , Chen Xingjiang , Li Xiaolong , Yang Le , Linghu Changkai , Tao Yao 
Published: September 2022

AbstractThe recycling of petroleum‐based polymers such as polypropylene (PP) and polyethylene (PE) is an effective means of reducing environmental pollution. However, the incompatible PP and PE blended waste is difficult to separate accurately, which reduces the quality of the recycled material. In this paper, the trifunctional acrylate monomer (trimethylolpropane triacrylate), peroxide (2,5‐dimethyl‐92,5‐di[tert‐butylperoxy] hexane) and free radical activity modifier (zinc dimethyldithiocarbamate) were applied to in situ generate the copolymer of isotactic polypropylene and high‐density polyethylene (iPP‐co‐HDPE) with a long‐chain co‐branched structure via a melt blending method. The co‐crystallization of the branched copolymer chain segments with the chemical identical homopolymers vastly improved the compatibility of iPP and HDPE components. This in situ co‐branching compatibility strategy resulted in a significant improvement in the mechanical properties of PE and PP mixed wastes. The temperature gradient extraction method was used to separate the co‐branching modified iPP/HDPE blends. The results confirm that the separated iPP‐co‐HDPE components have a highly co‐branched structure. The significant improvement in compatibility resulted in a large increase in elongation at break and impact strength of the iPP/HDPE blends, which provides an economic and effective method for the recycling of mixed PE and PP wastes.