bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modern view on the germ and embryogenesis of the urinary organs
Authors: Bulyk R. Ye. , Popeliuk O.-M. V. , Melnyk V. V. , Proniaiev D. V. 
Published: July 2022

Annotation. The literature is devoted to the analysis of scientific literature for the last 10 years from the electronic databases "PubMed" and "National Library of Ukraine named after V. I. Vernadsky", which are devoted to the study of the formation and development of organs and structures of the urinary system. The consequences of perinatal morphogenesis play the most essential role in the causes and contribution to many congenital malformations (CM), stillbirths, and infant morbidity. According to the Medical and Genetic Service of the Ministry of Health of Ukraine, up to 3,000 cases of CM of various organs and systems are recorded annually among newborns in Ukraine. CM of the genitourinary system ranks 3rd in frequency, among which CM of the female genitalia is up to 6 %. These figures are somewhat subjective, as a certain percentage of pathology of the female reproductive system is detected only when a girl reaches childbearing age, which greatly complicates the choice of methods and effectiveness of treatment. The rapid development of the genitourinary system of the fetus requires morphologists to comprehensively study the patterns of morphogenesis and the development of topographic and anatomical relationships of the reproductive system and urinary tract in the early period of human ontogenesis. The problem of combining information about the structural organization of the urinary tract and genital system into a consolidated morphofunctional unit is one of the cardinal problems of perinatal urology. The final formation of the urogenital organs is as follows. The initial kidneys' replacement with the permanent ones, metanephros, begins to form, from the same nephrogenic cord that gave rise to the primary kidney. The proper permanent renal parenchyma develops from the nephrogenic cord (renal tubuli). From the 3rd month, the permanent kidneys replace the mesonephros as the excretory organs already function. Thus, the embryonic development of the genitals is closely related to the development of the urinary tract and kidneys. Therefore, the CM of these two systems often occurs together. Active introduction of perinatal prophylaxis of urogenital organs requires modern approaches and methods of examination of intrauterine life. Therefore, the complex of embryotopographic studies attains special significance, having combined the consideration of organically critical periods of development with the understanding of the peculiarities of the spatial relationships of organs and structures of the genitourinary system.
CREATIVITY DEVELOPMENT IN CHILDREN OF PRESCHOOL AGE AS A FACTOR FOR THE ACTIVIZATION OF THEIR LEADERSHIP QUALITIES
Authors: Havryliuk Svitlana 
Published: July 2022

The article reveals the meaning of such concepts as “leadership qualities” and “creativity”, and defines the relationship between them in preschool-age children. Modern theoretical approaches to the problem of creativity development are presented, the connection between leadership qualities and creativity development of preschool-age children is analyzed. Factors influencing the development of leadership qualities of preschoolers such as family upbringing, age, and individual development, as well as features of children’s relationships in the immediate social environment (family, preschool, socio-cultural environment, etc.) are identified. The author emphasizes the importance of forming leadership qualities of the preschooler, namely such as responsibility; activeness; energy; persistence; demandingness; independence in performing the assigned task; communicativeness; organization; confidence; observation; initiative, creative approach to work. Emphasis is placed on the active support of leadership manifestations of preschool-age children in various types of creative activities: artistic, game, and creative.Thus, the author emphasizes that while communicating with children it is necessary to psychologically support them, i.e. to show optimism, encourage any manifestations of imagination, cultivate independence from an early age, stimulate children’s creativity, decision-making, and responsibility, rely on strong aspects of the character of a learner, create a situation of success, always take into account the opinion of the child, and show interest to the learner’s problems.The socio-pedagogical conditions necessary for the formation of leadership qualities of each learner are determined: taking into account the individual characteristics of the development of preschoolers and the level of formation of their creative and leadership qualities; purposeful formation of leadership qualities of preschool-age children in various types of creative activities (game, theatric, art and aesthetic); creating a favorable developmental environment by the means of enriching the educational space with a variety of cognitive information for the formation of children’s perception; development of communicative abilities, creative thinking, imagination, worldview, emotional and value sphere of preschool children; creating a situation for the child to succeed in various creative manifestations; formation of individual style of activity, high self-esteem of children, which stimulates them to actively take a part in creative activity.
Keywords: childhood; preschool age; creativity; leader; leadership qualities; leadership role; creative potential; creative thinking; game activity; pedagogical support of the development of leadership qualities of learners.
Influence of heat treatment on tribocorrosion properties of Ni-B composite coatings
Authors: Khoma M. , Mardarevych R. , Vynar V. , Vasyliv Сh. , Kovalchyk Yu. 
Published: July 2022

Various surface protection technologies, in particular, electrochemical, are used to increase the wear and corrosion resistance of steels and alloys. Composite electrochemical coatings (CEC) technology is more promising than "pure" galvanic coatings. Application of CEC increases the wear, corrosion and fatigue failure resistance of metals. Nickel often is chosen as a CEC matrix because it easily forms uniformly filled defect-free composite structures with many particles of the dispersed phase (DP).
Physical and mechanical properties of metal coatings determine practical application of such composition. The characteristics of nickel-based CEC are: high hardness and strength, significant corrosion resistance in atmospheric environment, as well as in alkali and mild acidy environments. An effective composition coating with tribological designation can be CEC Ni-B, received in the process of electrolysis from suspension of amorphous boron in nickel electrolyte. A new composite structure of matrix filled type Ni-Ni3B is formed after heat treatment. Composition and structure of coating is determined by regimes of diffusion annealing. Ni-B coatings increase wear resistance of steel in chlorine-based environments. The influence of low-temperature thermal treatment of Ni-B CEC on steel 09Mn2Si on their tribocorrosion behavior is investigated. It is shown that the structural factor has a decisive influence on the efficiency of such friction pairs. The CEC has the least wear and the most positive compromise electrode potential after vacuum annealing at 450°C, when the initial stage of solid-phase interaction of coating components with the formation of Ni-Ni3B occurs.
The Pruritic Urticarial Papules and Plaques of Pregnancy (PUPPP)
Authors: Kurniawan Riyan H. , Dimas Ugi U. , Arista Afria 
Published: July 2022

Objective: To report a rare case of pruritic urticarial papules and plaques of pregnancy (PUPPP) in multiparous woman and its literature review.Methods: A case report with literature review.Discussion: This article reports a multigravida woman, presented with aterm pregnancy with sign and symptoms of pruritic urticarial papules and plaques since the first trimester of pregnancy. This case supports the morphological variation of skin lesions in PUPPP, as the patient had lesions other than the characteristic urticarial papules and plaques, with hyperpigmentation skin changes. The management of this case include oral and topical corticosteroids, oral antihistamines and moisturizer is used to relieve pruritus and skin lesions.Conclusion: PUPPP should be included in the differential diagnosis to differentiate this entity from other dermatoses associated with pregnancy, in order to provide appropriate treatment and reassurance.Keywords: papules, plaques, pregnancy, pruritic, urticarial.

Abstrak
Tujuan: Untuk melaporkan kasus langka mengenai papula urtikaria pruritik dan plak pada kehamilan (PUPPP) perempuan multipara, membahas literatur terkait pada PUPPP.Metode: Laporan kasus dengan telaah literatur.Diskusi : melaporkan kasus perempuan multigravida, datang dalam usia kehamilan cukup bulan dengan tanda dan gejala papula, plak, urtikaria dan pruritus sejak trimester pertama kehamilan. Kasus ini mendukung variasi morfologi lesi kulit pada PUPPP, karena pasien memiliki lesi selain papula dan plak urtikaria yang khas, dengan perubahan kulit hiperpigmentasi. Penatalaksanaan kasus ini meliputi kortikosteroid oral dan topikal, antihistamin oral dan pelembab yang digunakan untuk meredakan pruritus dan lesi kulit.Kesimpulan: PUPPP perlu dimasukkan dalam diagnosis banding untuk membedakan entitas ini dari penyakit kulit lain yang terkait dengan kehamilan, untuk memberikan pengobatan dan pelayanan yang tepat.Kata kunci: kehamilan, , papula, plak, pruritus, urtikaria
Rectovaginal Fistulae in Post Repair Chronic Perineal Rupture
Authors: Santoso Budi I. , Tunggadewi Shirley A. , Sari Yulia M. 
Published: July 2022

Objective: To report and discuss the causes and management of rectovaginal fistula in post repair chronic total perineal rupture.Method: A case report, a 29-year-old female patient who came to Fatmawati General Hospital with complaints of anal incontinence 9 days after repair chronic total perineal rupture. Rectovaginal examination revealed a rectovaginal fistula 2 mm in diameter at 1.5 cm proximal to the hymenal ring.Discussion: Rectovaginal fistula is one of the complications after repair of hronic total perineal rupture which disturbs the quality of life of women. The patient was diagnosed with a rectovaginal fistula in post repair chronic total perineal rupture. Conservative management with wound care and administration of honey to the patient showed improved postoperative outcome.Conclusion: Anatomical identification of the anal sphincter complex, surgical technique and postoperative care are important in preventing complications following repair of chronic total perineal rupture repair.Keywords : obstetrics sphincter anal injury, postrepair chronic, rectovaginal fistulae .

Abstrak
Tujuan : Untuk melaporkan dan mendiskusikan penyebab dan tatalaksana kasus fistula rektovagina pasca repair ruptur perineum total lama.Metode: Sebuah laporan kasus, pasien perempuan 29 tahun yang datang ke RSUP Fatmawati dengan keluhan inkontinensia anal 9 hari pascarepair ruptur perineum total lama. Pemeriksaan rectovaginal menunjukkan fistula rektovagina diameter 2 mm pada 1,5 cm proksimal hymenal ring.Diskusi : Fistula rektovagina merupakan salah satu komplikasi pascarepair ruptur perineum total yang mengganggu kualitas hidup perempuan. Pasien didiagnsos fistula rektovagina pascarepair ruptur perineum total lama. Manajemen konservatif dengan perawatan luka dan pemberian madu pada pasien menunjukkan perbaikan luaran paska operasi.Kesimpulan: Identifikasi anatomis kompleks sfingter ani, teknik operasi dan perawatan pascaoperasi penting dalam mencegah komplikasi pascarepair ruptur perineum total lama.Kata kunci: cedera sfingter ani obstetri, fistula rectovagina, repair ruptur perineum total lama
ОСНОВНІ НАПРЯМИ ПІДГОТОВКИ, ПЕРЕПІДГОТОВКИ ТА ПІДВИЩЕННЯ КВАЛІФІКАЦІЇ ОСОБОВОГО СКЛАДУ З ОХОРОНИ АРСЕНАЛІВ, БАЗ ТА СКЛАДІВ РАКЕТ І БОЄПРИПАСІВ ЗБРОЙНИХ СИЛ УКРАЇНИ
Authors: Ворович Борис , Рогов Петро , Бутенко Микола , Мєзєнцев Олександр 
Published: July 2022

Системи безпеки та підрозділи охорони потенційно небезпечних об’єктів Збройних Сил України (особливо зберігання бойового запасу) повинні бути спроможні ефективно своєчасно виявляти та протидіяти диверсійно-розвідувальним групам, розвідувальним та ударним БпЛА, ракетним ударам, стихійним лихам тощо, терористам, диверсантам, кримінальним елементам та ін., а вогневе та технічне обладнання військових об’єктів повинно забезпечити їх надійній захист, охорону та оборону.
У статі наведено аналіз існуючої системи підготовки, перепідготовки та підвищення кваліфікації особового складу з охорони арсеналів, баз та складів ракет і боєприпасів Збройних Сил України. Досліджено Державні стандарти професійно-технічної освіти щодо підготовки робітників за професією 5169 “Охоронник”; чинники, які впливають на стан охорони та забезпечення живучості арсеналів, баз та складів ракет і боєприпасів; надано рекомендації щодо основних напрямків, особливостей та подальшого розвитку системи підготовки особового складу з охорони арсеналів, баз та складів ракет і боєприпасів Збройних Сил України.
СУТНІСТЬ І ЗМІСТ ФІЗИЧНОЇ ГОТОВНОСТІ МАЙБУТНІХ ОФІЦЕРІВ СУХОПУТНИХ ВІЙСЬК ДО ПРОФЕСІЙНОЇ ДІЯЛЬНОСТІ
Authors: Ягупов Василь , Коновалов Денис 
Published: July 2022

У статті проаналізовано сутність і зміст фізичної готовності майбутніх офіцерів Сухопутних військ до професійної діяльності. Проведено аналіз теоретичних праць фахівців із фізичного виховання, в яких формування фізичної готовності розуміється як процес переходу їх організму з одного стану в інший, що відбувається за рахунок прогресивних функціональних, морфологічних і біохімічних змін в їх організмі. Наголошено про відмінність фізичної готовності офіцерів різних видів і родів військ, а також різних спеціальностей.
Обґрунтовано, що фізична готовність майбутнього офіцера Сухопутних військ – це його фізичний стан як військового професіонала, який дозволяє йому успішно виконувати бойові та інші військово-професійні завдання за призначенням відповідно до вимог сучасного бою та стійко переносити фізичні навантаження військово-професійної, у тому числі й безпосередньо управлінської діяльності.
З урахуванням цілей, сутності та специфіки військово-професійної діяльності майбутніх офіцерів, сутності та змісту їх фізичної готовності згідно зі вимогами суб’єктно-діяльнісного, контекстного, системного та компетентнісного методологічних підходів, результатів узагальнення основних наукових джерел до визначення структурних компонентів психологічної, професійної та особистісної видів готовності майбутніх військових фахівців до професійної діяльності виокремлено ціннісно-мотиваційний, когнітивний, поведінково-діяльнісний, індивідуально-психічний і суб’єктний компоненти фізичної готовності офіцерів Сухопутних військ Збройних сил України до військово-професійної діяльності.
Differential Gut Microbiota Compositions Related With the Severity of Major Depressive Disorder
Authors: Zhong Qi , Chen Jian-jun , Wang Ying , Shao Wei-hua , Zhou Chan-juan , Xie Peng 
Published: July 2022

ObjectiveIncreasing evidence shows a close relationship between gut microbiota and major depressive disorder (MDD), but the specific mechanisms remain unknown. This study was conducted to explore differential gut microbiota compositions related to the severity of MDD.MethodsHealthy controls (HC) (n = 131) and MDD patients (n = 130) were included. MDD patients with Hamilton Depression Rating Scale (HDRS) score &lt;25 and ≥25 were assigned into moderate (n = 72) and severe (n = 58) MDD groups, respectively. Univariate and multivariate analyses were used to analyze the gut microbiota compositions at the genus level.ResultsThirty-six and 27 differential genera were identified in moderate and severe MDD patients, respectively. The differential genera in moderate and severe MDD patients mainly belonged to three (Firmicutes, Actinobacteriota, and Bacteroidota) and two phyla (Firmicutes and Bacteroidota), respectively. One specific covarying network from phylum Actinobacteriota was identified in moderate MDD patients. In addition, five genera (Collinsella, Eggerthella, Alistipes, Faecalibacterium, and Flavonifractor) from the shared differential genera by two MDD groups had a fair efficacy in diagnosing MDD from HC (AUC = 0.786).ConclusionsOur results were helpful for further exploring the role of gut microbiota in the pathogenesis of depression and developing objective diagnostic methods for MDD.
Clinical and Echocardiographic Outcomes of Transcatheter Tricuspid Valve Interventions: A Systematic Review and Meta-Analysis
Authors: Sannino Anna , Ilardi Federica , Hahn Rebecca T. , Lancellotti Patrizio , Lurz Philipp , Smith Robert L. , Esposito Giovanni , Grayburn Paul A. 
Published: July 2022

BackgroundMedically managed tricuspid regurgitation (TR) has detrimental outcomes. Transcatheter tricuspid valve interventions (TTVIs) represent an alternative to surgery in high-risk patients; however, only early experiences exist.AimThe aim of this study was to analyze the clinical and echocardiographic outcomes of TTVI.MethodsMEDLINE, ISI Web of Science, and SCOPUS databases were searched for studies published up to June 2021. Studies reporting data on outcome post-TTVIs were included. This study was designed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) requirements. The primary endpoint was all-cause mortality at 30-day and 1-year post-TTVI.ResultsOut of 2,718 studies, 27 were included. Notably, 30-day and 1-year all-cause mortalities were 5% (95% confidence interval [CI]: 4–8%, p &lt; 0.001) and 25% (95% CI: 12–45%, p = 0.016). Procedural success was associated with a 58% risk reduction in 1-year mortality vs. lack thereof (odds ratio 0.42, 95% CI: 0.27–0.66, p &lt; 0.001). TTVI is associated with a significant reduction in TR severity (TR EROA, mean difference [MD] 0.31 cm2; 95% CI: 0.23–0.39 cm2, p &lt; 0.001; regurgitant volume, MD 23.54 ml; 95% CI: 17.4–29.68 ml, p = 0.03) and increase in forward stroke volume (FSV, MD 3.98 ml; 95% CI: 0.11–7.86 ml, p = 0.04).ConclusionTTVI significantly reduces TR severity and increases FSV and is associated with improved survival at 1 year compared with patients without procedural success. Long-term outcomes compared with medical therapy await the results of ongoing pivotal trials; nonetheless, TTVIs appear to be a promising alternative to surgery for TR.
Bathymetric Highs Control the Along-Strike Variations of the Manila Trench: 2D Numerical Modeling
Authors: Ma Letian , Chen Lin , Cheng Zihua , Gerya Taras , Li Jiabiao 
Published: July 2022

The Manila Trench is located at the eastern boundary of the South China Sea (SCS). It develops through the subduction of the SCS beneath the Philippine Sea Plate (PSP) since the early Neogene, driven by the northwestern plate motion of the PSP. The northern segment of the Manila trench at around 18° N—21.5°N is characterized by an obvious eastward convex in the trench shape and abrupt changes of slab dip angle, whereas the southern segment of the Manila trench at around 15°N—18°N is featured by an almost straight NS-trending trench line and smooth subducting slab morphology. However, the cause for the along-strike variations along the Manila trench remains poorly understood. In this study, we use 2-D thermo-mechanical modeling to investigate how bathymetric highs embedded in the subducting slab affect the topography of overriding plate and the morphology of subducting plate. Three major factors of bathymetric highs are systematically examined: 1) the crustal properties, 2) the width, and 3) the thickness. Geodynamic results suggest that the most important factor controlling abrupt changes in dipping angle is the crustal properties of bathymetric highs. Also, reduction of crustal thickness and increasing the width of continental bathymetric highs favor the abrupt change of dipping angle, whereas thicker (≥25 km) bathymetric highs are more likely to be blocked in the subduction zone before slab break-off. According to our numerical modeling results, we suggest that dramatic changes in the dip angle in the northern Manila trench and the convex shape were caused by subduction of a large thin continental terrane, whereas the smooth morphology of subducting slab in the southern segment and straight trench were associated with normal oceanic subduction with small seamounts.
Predictive Value of Glycosylated Hemoglobin for Post-operative Acute Kidney Injury in Non-cardiac Surgery Patients
Authors: Wu Lan-Ping , Pang Ke , Li Bo , Le Yuan , Tang Yong-Zhong 
Published: July 2022

ObjectiveRecent studies have indicated that patients (both with and without diabetes) with elevated hemoglobin A1c (HbA1c) have a higher rate of acute kidney injury (AKI) following cardiac surgery. However, whether HbA1c could help to predict post-operative AKI in patients after non-cardiac surgery is less clear. This study aims to explore the predictive value of pre-operative HbA1c for post-operative AKI in non-cardiac surgery.MethodsWe reviewed the medical records of patients (≥ 18 years old) who underwent non-cardiac surgery between 2011 and 2020. Patient-related variables, including demographic and laboratory and procedure-related information, were collected, and univariable and multivariable logistic regression analyses were performed to determine the association of HbA1c with AKI. The area under the receiver operating curve (AUC), net reclassification improvement index (NRI), and integrated discriminant improvement index (IDI) were used to evaluate the predictive ability of the model, and decision curve analysis was used to evaluate the clinical utility of the HbA1c-added predictive model.ResultsA total of 3.3% of patients (94 of 2,785) developed AKI within 1 week after surgery. Pre-operative HbA1c was an independent predictor of AKI after adjustment for some clinical variables (OR comparing top to bottom quintiles 5.02, 95% CI, 1.90 to 13.24, P &lt; 0.001 for trend; OR per percentage point increment in HbA1c 1.20, 95% CI, 1.07 to 1.33). Compared to the model with only clinical variables, the incorporation of HbA1c increased the model fit, modestly improved the discrimination (change in area under the curve from 0.7387 to 0.7543) and reclassification (continuous net reclassification improvement 0.2767, 95% CI, 0.0715 to 0.4818, improved integrated discrimination 0.0048, 95% CI, -5e-04 to 0.0101) of AKI and non-AKI cases, NRI for non-AKI improvement 0.3222, 95% CI, 0.2864 to 0.3580 and achieved a higher net benefit in decision curve analysis.ConclusionElevated pre-operative HbA1c was independently associated with post-operative AKI risk and provided predictive value in patients after non-cardiac surgery. HbA1c improved the predictive power of a logistic regression model based on traditional clinical risk factors for AKI. Further prospective studies are needed to demonstrate the results and clinical application.