bluuebunny/crossref_metadata_2025_split huggingface dataset:
Appropriateness of indirect markers of muscle damage following lower limbs eccentric-biased exercises: A systematic review with meta-analysis
Authors: Chalchat Emeric , Gaston Anne-Fleur , Charlot Keyne , Peñailillo Luis , Valdés Omar , Tardo-Dino Pierre-Emmanuel , Nosaka Kazunori , Martin Vincent , Garcia-Vicencio Sebastian , Siracusa Julien 
Published: July 2022

Purpose
The aim of this review was to (1) characterize the time-course of markers of exercise-induced muscle damage (EIMD) based on the level of maximal voluntary contraction torque loss at 24-48h post-exercise (MVCloss24-48h), (2) identify factors (e.g., exercise and population characteristics) affecting the level of MVCloss24-48h, and (3) evaluate the appropriateness of EIMD markers as indicators of MVCloss24-48h.

Methods
Magnitude of change of each EIMD markers was normalized using the standardized mean differences method to compare the results from different studies. Time-course of EIMD markers were characterized according to three levels of MVCloss24-48h based on a clustering analysis of the 141 studies included. Association between MVCloss24-48h levels and participant´s characteristics or exercise type/modalities were assessed. Meta-regressions were performed to investigate the associations between MVCloss24-48h and EIMD markers changes at <6h, 24h, 48h, 72h and >96h after exercise.

Results
Time-course of EIMD markers recovery differs between levels of MVCloss24-48h. Training status and exercise type/modality were associated with MVCloss24-48h level (p<0.05). MVCloss24-48h was correlated to changes in myoglobin concentration (<6h), jump height (24h) and range of motion (48h) (p<0.001).

Conclusion
As the exercise could differently affect markers as function of the EIMD severity (i.e., MVCloss24-48h levels), different markers should be used as function of the timing of measurement. Mb concentration should be used during the first hours after the exercise (<6h), whereas jump height (24h) and range of motion (48h) could be used as surrogate for maximal voluntary contraction later. Moreover, training status and exercise type/modality could influence the magnitude of MVCloss24-48h.
Knowledge, attitudes and practices of community treatment supporters administering multidrug-resistant tuberculosis injections: A cross-sectional study in rural Eswatini
Authors: Peresu Ernest , Heunis J. Christo , Kigozi N. Gladys , De Graeve Diana 
Published: July 2022

Background
This study assessed knowledge, attitudes and practices (KAP) of lay community treatment supporters (CTSs) delegated with directly observed treatment (DOT) supervision and administration of intramuscular multidrug-resistant tuberculosis (MDR-TB) injections in the Shiselweni region in Eswatini.

Methodology
A cross-sectional survey among a purposive sample of 82 CTSs providing DOT and administering injections to MDR-TB patients was conducted in May 2017. Observations in the patients’ homes were undertaken to verify CTSs’ self-reported community-based MDR-TB management practices.

Results
Out of 82 respondents, 78 (95.1%) were female and half (n = 41; 50.0%) had primary education or lower. Over one-tenth (n = 12; 14.6%) had not attended a MDR-TB training workshop, but were administering injections. The overall KAP scores were satisfactory. Good self-reported community-based MDR-TB practices were largely verified through observation. However, substantial proportions of respondents incorrectly defined MDR-TB, were unaware of the treatment regimen, stigmatised patients, and underreported needlestick injuries. There was no statistically significant association between duration administering intramuscular injections, MDR-TB training, knowledge and attitudes, and good community-based MDR-TB management practices.

Conclusions
The gaps in the current KAP of CTSs in this setting raise questions about the timing, adequacy, design and content of community-based MDR-TB management training. Nonetheless, with appropriate training, lay CTSs in this region can be an option to complement an overstretched professional health workforce in providing DOT and MDR-TB injections at community level.
The effect of Cyclophilin D depletion on liver regeneration following associating liver partition and portal vein ligation for staged hepatectomy
Authors: Daradics Noemi , Horvath Gergo , Tretter Laszlo , Paal Agnes , Fulop Andras , Budai Andras , Szijarto Attila 
Published: July 2022

Aim
Associating Liver Partition and Portal vein ligation for Staged hepatectomy (ALPPS) is a modification of two-stage hepatectomy profitable for patients with inoperable hepatic tumors by standard techniques. Unfortunately, initially poor postoperative outcome was associated with ALPPS, in which mitochondrial dysfunction played an essential role. Inhibition of cyclophilins has been already proposed to be efficient as a mitochondrial therapy in liver diseases. To investigate the effect of Cyclophilin D (CypD) depletion on mitochondrial function, biogenesis and liver regeneration following ALPPS a CypD knockout (KO) mice model was created.

Methods
Male wild type (WT) (n = 30) and CypD KO (n = 30) mice underwent ALPPS procedure. Animals were terminated pre-operatively and 24, 48, 72 or 168 h after the operation. Mitochondrial functional studies and proteomic analysis were performed. Regeneration rate and mitotic activity were assessed.

Results
The CypD KO group displayed improved mitochondrial function, as both ATP production (P < 0.001) and oxygen consumption (P < 0.05) were increased compared to the WT group. The level of mitochondrial biogenesis coordinator peroxisome proliferator-activated receptor γ co-activator 1-α (PGC1-α) was also elevated in the CypD KO group (P < 0.001), which resulted in the induction of the mitochondrial oxidative phosphorylation system. Liver growth increased in the CypD KO group compared to the WT group (P < 0.001).

Conclusions
Our study demonstrates the beneficial effect of CypD depletion on the mitochondrial vulnerability following ALPPS. Based on our results we propose that CypD inhibition should be further investigated as a possible mitochondrial therapy following ALPPS.
Dynamic and Steady Model Development of Two-Chamber Batch Microbial Fuel Cell (MFC)
Authors: Harimawan Ardiyan 
Published: July 2022

As an alternative source of renewable energy that has piqued researchers’ interest, Microbial Fuel Cell’s (MFC) limitation of low power density requires further development. Various factors affect the performance, but performing all will be costly and time-consuming. Through a combination of dynamic and steady-state mathematical model modified from past research, effect of microbe types towards dynamic biofilm formation and stead-state OCV can be observed, followed by steady-state simulation to determine maximum power density and its’ corresponding voltage. Similarity with previous research has been observed, with maximum OCV of 838.93 mV achieved by heterotrophic biomass in 75-100 hours with biofilm thickness of 2.087 x 10-4 m, while generating maximum power density of 2050.12 mW//m2 and voltage of 408.16 mV. Lowest OCV value of 838.76 mV was observed in C. sporogenes in 450-475 hours with a biofilm thickness of 2.079 x 10-4 m, while the lowest value of maximum power density was observed in anaerobic microbial communities at 8.48 mW/m2 with voltage of 90.43 mV. Furthermore, it has been observed that variations with higher and lower results in higher stead-state OCV in the shortest amount of time, while increasing power density and its’ corresponding voltage. @font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:-536869121 1107305727 33554432 0 415 0;}@font-face {font-family:Calibri; panose-1:2 15 5 2 2 2 4 3 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:-469750017 -1073732485 9 0 511 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:"Times New Roman"; mso-ansi-language:EN-US;}.MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; font-size:10.0pt; mso-ansi-font-size:10.0pt; mso-bidi-font-size:10.0pt; font-family:"Calibri",sans-serif; mso-ascii-font-family:Calibri; mso-fareast-font-family:Calibri; mso-hansi-font-family:Calibri; mso-ansi-language:IN; mso-fareast-language:IN;}div.WordSection1 {page:WordSection1;}
Seagrass meadows in the Greek Seas: presence, abundance and spatial distribution
Authors: Panayotidis Panayiotis , Papathanasiou Vasillis , Gerakaris Vasileios , Fakiris Elias , Orfanidis Sotiris , Papatheodorou Georgios , Kosmidou Maria , Georgiou Nikos , Drakopoulou Vivi , Loukaidi Valia 
Published: July 2022

Abstract
Combined use of optical (satellite imagery) and acoustic (sidescan sonar) remote sensing techniques, as well as in situ methodologies (visual census; SCUBA diving, Towed Underwater Cameras, and Remotely Operated Vehicles) was employed to map the spatial distribution of seagrass habitats in the coastal waters of the Greek territory. Seagrass meadows were recorded over approximately 70% of the Greek coastline (Eastern Ionian, Aegean and Levantine Seas), and their surface area exceeded 2749.07 km2. Posidonia oceanica is clearly the dominant seagrass species in Greek Seas, covering the vast majority of seabed at depths between the shoreline and 25–30 m (or deeper in insular areas), followed by the species Cymodocea nodosa, Zostera noltei, and Halophila stipulacea, that are not widely distributed but are locally abundant in specific areas. Habitat suitability in terms of the of the seabed that is available for the growth of seagrass meadows (i.e., the spatial extent of coastal areas between the shoreline and the isobath of 20 m) and the seawater clarity conditions are highlighted as the critical factors for the formation of well-structured and extensive meadows. The results of this study are of great importance and usefulness for the effective management and conservation of valuable marine ecosystems and are given in the form of an openly accessible shapefile.
Redegewalt und doppelte Übersetzung
Authors: Weidner Daniel 
Published: July 2022

Zusammenfassung
Der Beitrag untersucht sprachliche und bildliche Darstellungen der Pfingstgeschichte als Urszene, das heißt als Inszenierung des Anfangs der christlichen Kirche und als Paradigma eines christlichen Verständnisses von Sprache. Er zeigt, wie diese Gründung mit dem Phänomen der Übersetzung, aber auch mit den Grenzen der Sprache (der »Zungenrede«) verbunden ist sowie wie diese Gründung in der Heilsgeschichte Israels situiert und durch den Jüngerkreis eine politische Ordnung instituiert wird. In diesem Rahmen erscheint auch der Geist als wesentlicher Bestandteil christlichen Sprechens sowie die erste spezifisch christliche Sprechhandlung: die Predigt des Petrus.
Entwichene Sprache
Authors: Haustein Jörg 
Published: July 2022

Zusammenfassung
Als pseudo-sprachliche Artikulation mag Zungenrede der Semantik entweichen, als zentrales theologisches Konstrukt der Pfingstbewegung ist sie jedoch mit Bedeutung überladen. Dieser Beitrag stellt die Diskussion um pfingstliche Glossolalie aus historischer, theologischer und sprachphilosophischer Perspektive vor und zeigt, wie das Ringen um eine »Nichtsprache« für das Verständnis von Theologie und Sprache fruchtbar sein kann.
Psychagogische Schockrhetorik für Zermürbte
Authors: Becker Matthias 
Published: July 2022

Zusammenfassung
Der Aufsatz widmet sich am Paradebeispiel der deliberativen Rhetorik des Hebräerbriefes der Frage, wie und zu welchem Zweck in neutestamentlichen Texten Bedrohungen sprachlich konstruiert und kommuniziert werden. Im modifizierenden Anschluss an theoretische Konzepte der Sozial- und Geisteswissenschaften werden sechs Sinndimensionen von Bedrohungskommunikation untersucht: die sachliche, soziale, zeitliche, emotionale, religiöse und die paränetische Sinndimension. Im Ergebnis zeigt sich, dass der als autoritätsbewusster Redner auftretende Verfasser mit seinen rhetorischen Drohgebärden die psychagogische Intention verfolgt, durch das mehrdimensionale Szenario eines drohenden Heilsverlusts den Glaubensabfall der Adressaten zu verhindern. Bedrohungskommunikation erscheint in diesem Licht folglich auch als eine Form sprachlicher Machtausübung.
D-dimer: old dogmas, new (COVID-19) tricks
Authors: Lippi Giuseppe , Mullier François , Favaloro Emmanuel J. 
Published: July 2022

Abstract
D-dimer is a fibrin degradation product encompassing multiple cross-linked D domains and/or E domains present in the original fibrinogen molecule, whose generation is only theoretically possible when hemostasis and fibrinolysis pathways are concomitantly activated. D-dimer measurement has now become a pillar in the diagnosis/exclusion and prognostication of venous thromboembolism (VTE) and disseminated intravascular coagulation (DIC), when incorporated into validated clinical algorithms and especially using age-adjusted diagnostic thresholds. Although emerging evidence is also supporting its use for predicting the duration of anticoagulant therapy in certain categories of patients, the spectrum of clinical applications is constantly expanding beyond traditional thrombotic pathologies to the diagnosis of acute aortic dissection, acute intestinal ischemia and cerebral venous thrombosis among others, embracing also clinical management of coronavirus disease 2019 (COVID-19). Recent findings attest that D-dimer elevations are commonplace in patients with severe acute respiratory syndrome (SARS-CoV-2) infection (especially in those with thrombosis), its value predicts the clinical severity (up to death) of COVID-19 and remains more frequently increased in COVID-19 patients with post-discharge clinical sequelae. Further, D-dimer-based anticoagulant escalation may be associated with a lower risk of death in patients with severe SARS-CoV-2 infection and, finally, D-dimer elevation post-COVID-19 vaccination mirrors an increased risk of developing vaccine-induced thrombocytopenia and thrombosis (VITT).
Black Feminist Organizing and Caribbean Cyberfeminisms in Puerto Rico
Authors: Stephens Miari Taina 
Published: July 2022

Abstract
This article centers Black feminist organizing in Puerto Rico, highlighting social media as a tool for racial and gender justice. Collaboration between Puerto Rican feminist organizations on social media platforms amplifies their on-the-ground work and demands. Mapping Caribbean Cyberfeminisms (2016) theorizes Caribbean cyberfeminisms as “knowledge-producing spaces of political thought and action” online by Caribbean feminists. I argue that through content creation and curation, reposting and sharing, commenting and captioning, broadcasting live, Black feminist collectives, organizations and projects in Puerto Rico use digital and virtual technologies to extend their Black feminist organizing and collaboration, building a Caribbean cyberfeminist network in the process.
Novel non-stop variant of the NR0B1 gene in two siblings with adrenal hypoplasia congenita
Authors: Ota Tomoko , Katsumata Noriyuki , Naiki Yasuhiro , Horikawa Reiko 
Published: July 2022

Abstract

Objectives
Mutations in the dosage-sensitive sex reversal-AHC critical region on the X chromosome, gene 1 (DAX-1, officially NR0B1), cause X-linked adrenal hypoplasia congenita (AHC) and hypogonadotropic hypogonadism (HHG). Salt-losing adrenal insufficiency usually occurs during the neonatal period or early childhood. We report a novel non-stop variant of NR0B1 in two siblings and their unusual clinical course.

Case presentation
The proband was a boy who presented with an unusual form of AHC with neonatal onset of growth failure and mild salt loss, but without cutaneous pigmentation or plasma ACTH elevation. His 4-year-old elder brother had been growing healthily, but carried an AHC diagnosis. A non-stop variant of NR0B1 (p.*471K) was demonstrated in the patients and their mother.

Conclusions
We identified a novel non-stop variant of NR0B1 in two siblings. Mild salt loss associated with hyperkalemia is a crucial diagnostic clue for AHC, even without apparent symptoms of glucocorticoid deficiency.
Negative photoresponse in Ti3C2T
x
MXene monolayers
Authors: Vorobeva Nataliia S. , Bagheri Saman , Torres Angel , Sinitskii Alexander 
Published: July 2022

Abstract
Two-dimensional transition metal carbides, nitrides, and carbonitrides, collectively known as MXenes, are finding numerous applications in many different areas, including optoelectronics and photonics, but there is limited information about their intrinsic photoresponse. In this study, we investigated the visible and near-infrared range photoresponse of Ti3C2T
x
, the most popular MXene material to date. The electrical measurements were performed on devices based on individual monolayer Ti3C2T
x
MXene flakes, which were characterized by a variety of microscopic and spectroscopic methods. For MXene devices with different electrode layouts, the current reproducibly decreased under illumination with either white light or lasers with different wavelengths in the visible and near-infrared region, thus demonstrating a negative photoresponse. The understanding of the intrinsic photoresponse of Ti3C2T
x
should facilitate the optoelectronic and photonic applications of MXenes.
Hierarchical visible-infrared-microwave scattering surfaces for multispectral camouflage
Authors: Huang Yun , Zhu Yining , Qin Bing , Zhou Yiwei , Qin Rui , Ghosh Pintu , Qiu Min , Li Qiang 
Published: July 2022

Abstract
Multispectral camouflage, especially for the infrared-microwave range, is an essential technology for the safety of facilities, vehicles, and humans. So far, it has been realized mainly by high infrared specular reflection and high microwave absorption. However, external infrared sources can expose the target through specular reflection; also, the heat production from microwave absorption can increase the infrared radiation. This work proposes a multispectral camouflage scheme based on hierarchical visible-infrared-microwave scattering surfaces to address these issues. The proposed device exhibits: (1) low infrared emissivity (ε
8–14 μm = 0.17) and low infrared specular reflectivity (R

s

8–14 μm = 0.13), maintaining low infrared radiation and capability to overcome the presence of an external infrared source simultaneously; (2) high scattering in microwave range, with −10 dB radar cross section reduction bandwidth of 8–13 GHz, simultaneously achieving microwave camouflage and reducing the heat production; (3) tunability of color for visible camouflage. This work proposes a method to control scattering over visible-infrared-microwave bands, thereby introducing a new design paradigm for modern camouflage technology.
Chemical thermodynamics of ternary M-An(VI)-CO3 system (M = Mg, Ca, Sr, and Ba)
Authors: Jo Yongheum , Lee Jun-Yeop , Yun Jong-Il 
Published: July 2022

Abstract
This review provides an overview of the chemical thermodynamics on ternary earth-alkaline metal-actinyl-tricarbonate systems (i.e., M-AnO2-CO3, M = Mg, Ca, Sr, and Ba) and discusses the aqueous complexation and dissolution/precipitation equilibrium for these ternary aqueous systems. The aqueous ternary U(VI) carbonate species are remarkably predominant in the U(VI) speciation under natural environmental conditions at ambient temperature and moderate ionic strength condition, while the omnipresence, according to recent studies, would be hindered by an increase in temperature and ionic strength. With respect to the ternary solid U(VI) carbonate phases, most of the previously reported data have been focused on physical properties and thus a notable lack of available data on chemical thermodynamic properties, i.e., solubility product constant, has been identified. Nevertheless, substantial influences of these ternary M-AnO2-CO3 systems on the aqueous speciation and the solubility limiting phase under the natural environmental condition are taken into account according to the thermodynamic calculation. The authors point out that the completeness of the chemical thermodynamic model for predicting the chemical behavior of actinides in nature can be further improved on the basis of a sufficient understanding of ternary M-AnO2-CO3 systems.
Continuous Tracking of Task Parameters Tunes Reaching Control Online
Authors: De Comite Antoine , Crevecoeur Frédéric , Lefèvre Philippe 
Published: July 2022

AbstractA hallmark of human reaching movements is that they are appropriately tuned to the task goal and to the environmental context. This was demonstrated by the way humans flexibly respond to mechanical and visual perturbations that happen during movement. Furthermore, it was previously showed that the properties of goal-directed control can change within a movement, following abrupt changes in the goal structure. Such online adjustment was characterized by a modulation of feedback gains following switches in target shape. However, it remains unknown whether the underlying mechanism merely switches between prespecified policies, or whether it results from continuous and potentially dynamic adjustments. Here, we address this question by investigating participants’ feedback control strategies in presence of various changes in target width during reaching. More specifically, we studied whether the feedback responses to mechanical perturbations were sensitive to the rate of change in target width, which would be inconsistent with the hypothesis of a single, discrete switch. Based on movement kinematics and surface EMG data, we observed a modulation of feedback response clearly dependent on dynamical changes in target width. Together, our results demonstrate a continuous and online transformation of task-related parameters into suitable control policies.
Navigating the Statistical Minefield of Model Selection and Clustering in Neuroscience
Authors: Király Bálint , Hangya Balázs 
Published: July 2022

AbstractModel selection is often implicit: when performing an ANOVA, one assumes that the normal distribution is a good model of the data; fitting a tuning curve implies that an additive and a multiplicative scaler describes the behavior of the neuron; even calculating an average implicitly assumes that the data were sampled from a distribution that has a finite first statistical moment: the mean. Model selection may be explicit, when the aim is to test whether one model provides a better description of the data than a competing one. As a special case, clustering algorithms identify groups with similar properties within the data. They are widely used from spike sorting to cell type identification to gene expression analysis. We discuss model selection and clustering techniques from a statistician’s point of view, revealing the assumptions behind, and the logic that governs the various approaches. We also showcase important neuroscience applications and provide suggestions how neuroscientists could put model selection algorithms to best use as well as what mistakes should be avoided.