bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association Between Self-Perceived Stigma and Quality of Life Among Urban Chinese Older Adults: The Moderating Role of Attitude Toward Own Aging and Traditionality
Authors: Sun Tao , Zhang Shu-E , Yan Meng-yao , Lian Ting-hui , Yu Yi-qi , Yin Hong-yan , Zhao Chen-xi , Wang Yan-ping , Chang Xiao , Ji Ke-yu , Cheng Si-yu , Wang Xiao-he , Huang Xian-hong , Cao De-pin 
Published: February 2022

BackgroundAgeism is a global challenge, which leads to a range of adverse outcomes for elderly people worldwide, which maybe more severe among urban older adults in a competitive society. However, how self-perceived ageism influences the quality of life in a sample of urban older adults remains inconclusive.ObjectivesThe current study aims to assess the status of self-perceived stigma among urban Chinese older adults, identify its relationship with quality of life, and further explore whether both attitude toward own aging and traditionality moderate this relationship.Materials and MethodsPrimary data were collected through cross-sectional surveys among urban older adults in three provinces of China from October 2019 to December 2020. A total of 764 urban older adults were valid participants (effective response rate = 81.28%) and completed questionnaires via anonymous face-to-face interviews. Socio-demographic factors, self-perceived stigma, attitude toward own aging, traditionality, and quality of life were assessed using questionnaires that included the Self-perceived Stigma, Attitude Toward Own Aging, Traditionality, and SF-8 Scales.ResultsFor urban Chinese older adults, the average score of self-perceived stigma was 2.041 ± 0.726. Self-perceived stigma (β = −0.391, p &lt; 0.05) and attitude toward own aging (β = −0.211, p &lt; 0.05) both influenced quality of life. Additionally, attitude toward own aging (β = −0.530, p &lt; 0.05) and traditionality (β = −0.525, p &lt; 0.05) moderated the association between self-perceived stigma and quality of life. Simple slope analysis revealed that when the level of negative attitude toward own aging and traditionality was higher, the strength of the influence of self-perceived stigma on quality of life was stronger.ConclusionUrban Chinese older adults were aware of the self-perceived stigma, which contributes to decreased quality of life. Attitude toward own aging and traditionality could moderate the association between self-perceived stigma and quality of life. When negative attitudes toward own aging and traditionality are higher, self-perceived stigma has a greater effect on the quality of life. More interventions related to relieving self-perceived stigma, traditionality, and negative attitude toward own aging should be considered to build a new modern society that emphasizes health, friendliness, well-being, and dignity for all ages.
Squeezing More Juice out of Dielectric Elastomer Generators
Authors: Rosset Samuel , Anderson Iain A. 
Published: February 2022

Dielectric elastomer generators are soft structures capable of converting mechanical energy into electrical energy. Here, we develop a theoretical model of the triangular harvesting cycle that enables the harvesting of most of the available electrical energy while not requiring active monitoring of the charge-voltage state on the DEG. This cycle is therefore interesting for small-scale generators for which a monitoring circuit would be energetically too costly. Our model enables the identification of the optimal value of the circuit’s parameters such as storage capacitor and priming voltage values and show that for capacitance swings up to 6, 94% of the available electrical energy can be harvested. The model is experimentally validated with a conical generator, and the effect of non-constant deformation amplitudes is examined. Energy densities up to 46 mJcm−3 were obtained for an electric field of 50 V µm−1.
Surgery and Surgery Approach Affect Survival of Patients With Stage I-IIA Small-Cell Lung Cancer: A Study Based SEER Database by Propensity Score Matching Analysis
Authors: Chen Xiaolu , Zhu Jia-Li , Wang Huaying , Yu Wanjun , Xu Tao 
Published: February 2022

PurposeThe purpose of this study was to observe the significance of surgery and its approach in stage I-IIA (according to 8th American Joint Committee on Cancer Staging Manual) small-cell lung cancer (SCLC) using the Surveillance, Epidemiology, and End Results (SEER) database.Patients and MethodsA total of 1,421 patients from ages 31 to 93 years who were diagnosed with stage I-IIA SCLC in the SEER database from 2010 to 2015 were analyzed. The 1:1 propensity score matching analysis was used to minimize the effect of selection bias, and 355 pairs of patients' data was performed subsequent statistical analysis. K–M analysis and a Cox proportional hazards model were used to observe the role of surgery and other clinical features in the patients' prognoses on cancer-specific survival (CSS).ResultsOverall, within the whole cohort, the 3- and 5-year CSS rates were 41.0 and 34.0%, respectively. In a Cox regression that adjusted for other clinical features, patients were more likely to benefit from the surgery [hazard ratio (HR) 0.292, 95% confidence interval (CI) 0.237–0.361, P &lt; 0.001]. Unadjusted 5-year cancer-specific survival among those with surgery was 55.0%, compared with 23.0% among those without surgery. In the propensity scored-matched dataset, however, 5-year CSS among those with surgery was 54.0%, compared with 17.0% among those without surgery (HR 0.380, 95%CI 0.315–0.457, P &lt; 0.001). In patients who received surgery, cases with lobectomy had a better 5-year CSS than those without lobectomy (65.0 vs. 39.0%). The lobectomy might be a protective factor for patients who underwent resection in CSS (HR 0.433, 95%CI 0.310–0.604, P &lt; 0.001).ConclusionsWe suggested that the surgery and lobectomy were the independent prognostic as well as the protective factors in stage I-IIA SCLC patients. We recommended that patients with no surgical contraindications receive surgery, preferably, lobectomy.
Mismatch Amplification Mutation Assays of Chikungunya Virus and O'nyong-Nyong Virus; A Simple and Reliable Method for Surveillance and Identification of Emerging Alphaviruses
Authors: Lwande Olivia Wesula , Luande Verah Nafula , Pereira de Freitas Amanda , Tajedin Leila , Ahlm Clas , Näslund Jonas , Evander Magnus , Bucht Göran 
Published: February 2022

BackgroundThe mosquito-borne alphaviruses chikungunya virus (CHIKV) and o'nyong-nyong virus (ONNV) are closely related Alphaviruses that belong to the Semliki forest virus serocomplex. The two viruses are associated with large outbreaks with significant morbidity. However, they are transmitted by different mosquito vectors and accordingly need different prevention strategies. The viruses are difficult to distinguish clinically and there is a lack of sensitive and specific assays that can discriminate between CHIKV and ONNV. Therefore, there is a need for new methods that may be able to determine the true burden of the diseases caused by these viruses, especially in resource-poor settings.MethodTo distinguish between CHIKV and ONNV, we designed and optimized two genetic methods, melt analysis of mismatch amplification mutation assay (Melt-MAMA) and agarose gel-based mismatch amplification mutation assay (Agarose-MAMA). The identification was based on single nucleotide polymorphisms using two competing forward primers and a common reverse primer that targeted selected sites in the envelope genes (E1 and E2). A specific shift in the melting point and mobility on agarose gels was obtained by tailing one of the two competing primers with a G/C-rich stretch of nucleotides.ResultsThe melting point analyses by real-time polymerase chain reaction (qPCR Melt-MAMA) or gel-shift assay (Agarose-MAMA assay) for CHIKV and ONNV were found to be reproducible and the sensitivity of the two assays was estimated at under 100 template copies/reaction. Furthermore, no cross-reactivity with related viruses of the same serocomplex such as Mayaro virus, Ross River virus or Semliki forest virus was detected, or with other viruses such as Sindbis virus (Alphavirus), West Nile virus, dengue virus (Flavivirus), Inkoo virus and Tahyna virus (Orthobunyavirus). The results from the two assays were comparable when the obtained amplicons were analyzed by Melt-MAMA or by Agarose-MAMA.ConclusionHerein we present reliable and robust methods that can discriminate between CHIKV and ONNV. These methods can be used in well-equipped laboratories and basic clinical settings (e.g., in developing countries), as well as in field situations. The approach may also be applicable in the distinction of other closely-related mosquito-borne viruses that belong to the same serogroup.
Analysis of Students’ Ability in Using Personal Pronouns in Narrative Text at Tenth Grade of SMA Swasta Pencawan Medan During Covid-19 Pandemic
Authors: Tamba Sri , Pasaribu Rosija , Pangaribuan Martauli , Loi Oktaria Putri , Tarigan Sri Ninta 
Published: February 2022

Abstract
The research objectives are to find the abilty of the students out in using the personal pronouns in the Narrative Text at Grade Ten of SMA Swasta Pencawan Medan During Covid-19 Pandemic and to know more about the the factors that affect the ability of the students in using the personal pronouns in the Narrative text. The research subject is 37 students. They are from X-Science class of SMA Swasta Pencawan Medan in school years 2020/2021. There are 18 students who get very good score (score: 80-100). It can be stated into percentage form, there are 48.65 % of students who can get very good scores. Meanwhile there are 13 students who get good score (score: 70-79). It can be stated into percentage form that there are 35.14 % of students can achieve good score. 4 students get fair score (score: 60-69). It can be stated into percentage form, that there are 10.81 % of the students who can achieve fair scores. 2 students get low score (score: 50-59). It can be stated into percentage form that there are 5.41 % who get low scores. The total scores of the students are 2,870 and the mean scores is 77.57. It can be concluded that the students score generally is above KKM (Minimum Criteria of Mastery Learning). There are some factors that affect the abilty of the students in using the personal pronoun in the narrative text, they are: the students’ interested in learning narrative text, facilities in the school or used by the English teachers, students’ motivation, adequate time, and due to covid-19 pandemic, so the students’ have been joining virtual class (online class) until now. According to the students’ opinion, Virtual class is not very effective for students in learning English, especially when the students learn about the personal pronoun in narrative text.
Key Words: An Analysis, Students’ Ability, Personal Pronoun, Narrative Text
EFFECT OF USING CLUSTERING TECHNIQUE ON STUDENTS’ACHIEVEMENT IN WRITING NARRATIVE TEXT
Authors: Madin Madina 
Published: February 2022

This research presents a research report on students’achievement in writing narrative text by using clustering technique between two groups: experimental and control group. The design of this study is experimental group. The population of this study is eleven grade students of SMK Sandhy Putra 2 Medan in the academic year 2017/2018. The samples of this research were the students of Class X-TKJ1and TKJ2 consisting 31 students as the experimental group, and Class X-TB1 and X-TB2 consisting 31 students as the control group. The data of the test were analyzed by using t-test formula to know the difference of the students’ achievement in writing narrative text. In the pre-test the mean of score of the experimental group 62,93 and the mean of post test of 79,54 and the control group is 61,23 and the post-test 51,06 the results of the t-test 6,10>2,000

Key Words : Clustering technique, Narrative text
HULING HULING ACCA (HHA) AS ENGLISH RIDDLES FOR FUN EFL LEARNING STRATEGY IN TOBA
Authors: Hutabarat Sadrakh Saprianto , Aura Shafitri Syabillah , Tarigan Mariana , S.S., M.Hum Azizah Husda 
Published: February 2022

Abstract

In this study the researchers want to describe about Huling-huling Acca (Hha) As English Riddles For Fun EFL Learning Strategy In Toba. In conducting the researchers, the research designis Etnografi is a type of qualitative research design. To collect the data the study employ the interview with five questions and observation given to children and the people of Sosordolok, Toba Samosir. This study investigest of HHA as English riddles with five types of values according by (Paul Suparno), there are; sosialismy, adversity quotient, responsibilities, environment, self-relience. As a result the study, It turns out that a lot of kids and people around here are poorly informed about huling-huling acca (hha). As researchers carried out further research, many people which had come to understand hha have proved invaluable. To illustrate "sae mangan ro siganjang obuk" so the values can can in this example of hha are moral and ethical. Because it should have finished eating the rest of the dirt must be eaten. Therefore these hha can be made into a fun learning medium and as an enhanced batak culture in its own language.
Key words: Huling-huling acca, english riddles, EFL, learning strategy
Measurement of Urinary Ammonium Using a Commercially Available Plasma Ammonium Assay
Authors: Gruzdys Valentinas , Cahoon Kenneth , Pearson Lauren , Raphael Kalani L. 
Published: February 2022

Key Points

Plasma ammonium assay reliably quantifies urine ammonium at physiologic concentrations.The enzymatic method compares well with the formalin titration method and is suitable for routine clinical use.

Background
Determination of urinary ammonium excretion is helpful in evaluating patients with acid-base disorders, chronic kidney disease, and nephrolithiasis. However, urinary ammonium levels are only measured by specialized laboratories in the United States, limiting widespread implementation. We evaluated the performance of a plasma ammonium assay to quantify urinary ammonium excretion and also determined ammonium stability under a variety of conditions.

Methods
An enzymatic plasma ammonium assay (Randox) was modified to measure urinary ammonium concentration. Urine samples were diluted 40-fold and then assayed on an Abbott Architect ci8200 analyzer. Assay precision, limit of quantitation, and linearity were determined. The method was compared against the formalin titration method, and stability studies were conducted at different temperatures and pH.

Results
After dilution, the assay had total precision of 18% at 2.54 mmol/L, 5% at 15.58 mmol/L, and 2% at 29.49 mmol/L, with a limit of quantitation of 2.92 mmol/L. Assay performance was linear in the range of 0.7–45 mmol/L. Method comparison against the formalin method showed a slope of 0.98 and intercept of –0.37 mmol/L. Urinary ammonium was determined to be stable for 48 hours at room temperature and for 9 days at 4°C and –20°C at pH 5.6–6.3. Ammonium was less stable at pH 3.8 and 8.5. When stored at –80°C, urinary ammonium was stable for at least 24 months.

Conclusions
The modified enzymatic plasma ammonium assay reliably quantifies urine ammonium at physiologic concentrations. It compares well with the formalin titration method and is suitable for routine clinical use on an automated chemistry analyzer.
Wegener’s Granulomatosis in the Practice of Otorhinolaryngologist. Clinical Case
Authors: Затолока П.А. , Родько С.С. , Рожкова А.В. 
Published: February 2022

Приводятся данные авторов по клиническому наблюдению болезни Вегенера. Особенностью данного наблюдения является то, что манифестацией заболевания было поражение уха, которое длительное время было единственным симптомом болезни, что затруднило постановку основного диагноза. Признаки генерализации процесса проявили себя через 2 месяца. Потребовались многочисленные обследования, а также проведение дифференциального диагноза с рядом заболеваний. Несмотря на то что гранулематоз Вегенера встречается редко, врачу-оториноларингологу необходимо знание клинической картины, особенностей течения болезни, поскольку при первичном локальном развитии гранулематозного процесса в лорорганах диагностика заболевания представляет трудности. Учитывая системный характер заболевания, сложность диагностики на ранних этапах, высокую летальность в отсутствие адекватной и своевременно начатой терапии, данный клинический случай заслуживает особого внимания. Лечение данной категории пациентов должно проходить при участии ревматолога.
The authors’ data based on the clinical observation of Wegener’s disease are provided. The unique feature of this observation is that the disease manifested itself as an ear lesion, which was the only symptom of the disease for a long time, making it difficult to establish the main diagnosis. Constitutional symptoms developed in 2 months. Numerous examinations as well as differential diagnosis were required. Despite the fact that Wegener’s granulomatosis is a rare disease, an otorhinolaryngologist needs to understand the clinical presentation and the features of disease progression, since in case of primary local development of the granulomatous process in the ENT organs, the diagnosis becomes difficult. Taking into account the systemic nature of the disease, the complexity of early diagnostics, and high mortality in the absence of adequate and timely initiated therapy, this clinical case deserves special attention. A rheumatologist should be involved when treating this category of patients.
Contribution of Transforming Growth Factor β1, Endothelin-1, Type IV Collagen, and Polymorphisms of Their Genes in Arterial Remodeling
Authors: Левкович Т.В. , Пронько Т.П. 
Published: February 2022

Сердечно-сосудистые заболевания остаются основной причиной смертности в Республике Беларусь. Поиск новых индикаторов повышенного кардиоваскулярного риска остается актуальной задачей медицинской науки. Поскольку ремоделирование артерий предшествует многим сосудистым катастрофам, то обнаружение факторов, способствующих негативным функциональным и морфологическим изменениям в артериальных сосудах, позволит активизировать лечебные и профилактические мероприятия. К таким факторам ремоделирования артерий относятся трансформирующий фактор роста β1 (ТФРβ1), коллаген IV типа, эндотелин-1 (ЭТ-1). Приведены данные исследований, подтверждающие их связь с атеросклерозом иартериосклерозом. В статье освещены вопросы участия ТФРβ1, коллаген IV типа и ЭТ-1 в возникновении сердечно-сосудистых катастроф. Особый интерес представляет изучение полиморфизмов единичных локусов представленных факторов ремоделирования. В статье систематизированы и обобщены научные сведения о некоторых полиморфизмах генов ТФРβ1, ЭТ-1, α1 цепи коллагена IV типа, сделан акцент на их ассоциации с сердечно-сосудистыми заболеваниями в различных популяциях.
Cardiovascular diseases remain the main cause of death in the Republic of Belarus. The search for new indicators of the increased cardiovascular risk remains an urgent task of medical science. Since the remodeling of arteries precedes many vascular accidents, the detection of the factors that contribute to negative functional and morphological changes in arterial vessels will let to activate therapeutic and preventive measures. These factors of arterial remodeling include transforming growth factor β1 (TGFβ1), type IV collagen, endothelin-1 (ET-1). The research data that confirm their connection with atherosclerosis and arteriosclerosis are presented. The article highlights the participation of TGFβ1, type IV collagen, and ET-1 in the occurrence of cardiovascular accidents. The study of polymorphisms of single loci of the presented remodeling factors and their combinations is of particular interest. In the article, there is systematized and summarized the scientific information about some polymorphisms of the genes TGFβ1, ET-1, α1 chain of type IV collagen; the emphasis is placed on their association with cardiovascular diseases in various populations.
Non-Invasive Screening Methods оf Colorectal Cancer
Authors: Ерзинкян Ф.В. , Красный С.А. , Абельская И.С. , Ребеко И.В. 
Published: February 2022

Скрининг колоректального рака (КРР) вносит существенный вклад в тенденцию снижения заболеваемости и смертности от данной патологии. Ценность скрининга отражается в его способности предотвращать заболеваемость рака толстой кишки путем удаления полипов (предрака) и выявлять ранние стадии КРР. В статье проанализированы разные неинвазивные методы скрининга, а также продемонстрированы результаты собственного проекта. Анализ полученных результатов свидетельствует о низкой диагностической чувствительности (ДЧ) теста FIT в диагностике всех полипов - 11,7%, диагностическая специфичность (ДС) теста составила 94,4%. ДЧ теста FIT в диагностике аденоматозных полипов более 0,6 см составила 15,1%, ДС - 85,2%. Анализируя результативность метода FIT в диагностике КРР, следует отметить, что диагностическая специфичность теста составила 93,6% при крайне низкой диагностической чувствительности теста - 33,3% в отношении всех выявленных при скрининге случаев КРР. Положительной была только одна проба FIT из шести.
Screening of colorectal cancer makes a significant contribution to the downward trend in morbidity and mortality from this pathology. The value of screening is reflected in its ability to prevent the incidence of colon cancer by removing polyps and detecting early stages of colorectal cancer. In the article, there are analyzed various non-invasive screening methods and the results of our own project are demonstrated. The analysis of the obtained results indicates a low diagnostic sensitivity of the FIT test in the diagnostics of all polyps - 11.7%, the diagnostic specificity (DS) of the test was 94.4%. The diagnostic sensitivity of the FIT test in the diagnostics of adenomatous polyps of more than 0.6 cm was 15.1%, and the DS was 85.2%. Analyzing the effectiveness of the FIT method in the diagnostics of colorectal cancer, it should be noted that the diagnostic specificity of the test was 93.6% with extremely low diagnostic sensitivity of the test - 33.3% for all cases of colorectal cancer detected during screening. Only one FIT test out of six was positive.
Perancangan Sistem Informasi E-library Pada SMP Negeri Pada Tapalang Barat Berbasis Website
Authors: Sunarsih Sunarsih , Assidiq Muhammad , Qashlim A.Akhmad 
Published: February 2022

Perpustakan sekolah memiliki peran dan fungsi yang strategis dalam mengembangkan potensi peserta didik dari seluruh civitas akademika yang ada di lingkungan sekolah. Perpustakaan bagian sumber belajar yang dimiliki oleh setiap sekolah, perpustakaan yang masih manual merupakan hal yang perlu dibuatkan sistem yang dapat membantu aktivitas administrasi. Dengan adanya e-library pengguna dapat melakukan akses secara bersama-sama dengan pengguna lain tanpa perlu menunggu antrian. Proses pencarian lebih mudah dan cepat karena dibantu oleh mesin pencari informasi yang menggunakan database. Sistem ini menghadirkan varian tentang perpustakaan digital antara lain bagian halaman pengguna menyajikan buku-buku yang tersedia pada perpustakaan SMP Tapalang Barat.