bluuebunny/crossref_metadata_2025_split huggingface dataset:
Screening of possible biomarkers and therapeutic targets in kidney renal clear cell carcinoma: Evidence from bioinformatic analysis
Authors: Peng Longfei , Cao Zhangjun , Wang Qi , Fang Lu , Yan Songbai , Xia Dian , Wang Jinyou , Bi Liangkuan 
Published: October 2022

Renal cell carcinoma (RCC), as one of the most common urological malignancies, has many histologic and molecular subtypes, among which clear cell renal cell carcinoma (ccRCC) is one of the most common causes of tumor-related deaths. However, the molecular mechanism of ccRCC remains unclear. In order to identify the candidate genes that may exist in the occurrence and development of ccRCC, microarray datasets GSE6344, GSE16441, GSE36895, GSE53757 and GSE76351 had been downloaded from Gene Expression Omnibus (GEO) database. Apart from that, the differentially expressed genes (DEGs) were screened through Bioinformatics &amp; Evolutionary Genomics. In addition, the protein-protein interaction network (PPI) was constructed, and the module analysis was performed using STRING and Cytoscape. By virtue of DAVID online database, GO/KEGG enrichment analysis of DEGs was performed. Consequently, a total of 118 DEGs were screened, including 24 up-regulated genes and 94 down-regulated genes. The plug-in MCODE of Cytoscape was adopted to analyze the most significant modules of DEGs. What’s more, the genes with degree greater than 10 in DEGs were selected as the hub genes. The overall survival (OS) and disease progression free survival (DFS) of 9 hub genes were analyzed through GEPIA2 online platform. As shown by the survival analysis, SLC34A1, SLC12A3, SLC12A1, PLG, and ENO2 were closely related to the OS of ccRCC, whereas SLC34A1 and LOX were closely related to DFS. Among 11 SLC members, 6 SLC members were highly expressed in non-cancerous tissues (SLC5A2, SLC12A1, SLC12A3, SLC34A1, SLC34A2, SLC34A3). Besides, SLC12A5 and SLC12A7 were highly expressed in ccRCC. Furthermore, SLC12A1-A7, SLC34A1 and SLC34A3 were closely related to OS, whereas SLC12A2/A4/A6/A7 and SLC34A1/A3 were closely related to DFS. In addition, 5 algorithms were used to analyze hub genes, the overlapping genes were AQP2 and KCNJ1. To sum up, hub gene can help us understand the molecular mechanism of the occurrence and development of ccRCC, thereby providing a theoretical basis for the diagnosis and targeted therapy of ccRCC.
Primary care provider's job satisfaction and organizational commitment after COVID-19 restrictions ended: A mixed-method study using a mediation model
Authors: Wang Quan , Liu Xinyu , Wang Ting , Zhu Zemeng , Yang Li , Guo Shasha , Li Hui , Sun Qiang 
Published: October 2022

ObjectivesMore and more countries have decided to cancel most or even all COVD-19 restrictions. However, it is unclear how ending of restrictions will affect primary care providers' job satisfaction and organizational commitment. Our objectives are to explore the current status and possible change in primary care providers' job satisfaction and organizational commitment after massive restriction policies ended in China.MethodsThis was a mixed-method study that utilized structured questionnaires and semi-structured qualitative individual interviews. The 20-item Minnesota Satisfaction Questionnaire (MSQ) and 25-item organizational commitment survey were adopted to assess job satisfaction and organization commitment. Descriptive statistics and mediation models, as well as inductive thematic analysis, were used to analyze quantitative and qualitative data.ResultsA total of 18 interviews and 435 valid survey responses were included in our analysis. The average scores for job satisfaction and organizational commitment were 80.6 and 90.8. The thematic analysis revealed one major theme: ethical and moral responsibility to provide care as primary care providers, on which we established a mediation model. The mediation analysis revealed that normative commitment could positively affect the other four dimensions of organizational commitment and job satisfaction. The direct effect of affective commitment on job satisfaction was significant (LLCI = 0.11, ULCI = 0.31), and the mediators were identified to have a partial mediating effect instead of a total mediating effect.ConclusionAfter COVID-19 restrictions end, the job satisfaction and organizational commitment of primary care providers will return to levels before the pandemic and during this estimated process, a brief rise in resignation is predictable. The normative commitment positively affects the other four dimensions of organizational commitment and job satisfaction for primary care providers, which suggests a possible way to motivate primary care providers when restrictions end.
Muscle adaptations in acute SCI following overground exoskeleton + FES training: A pilot study
Authors: Hohl Kristen , Smith Andrew C. , Macaluso Rebecca , Giffhorn Matthew , Prokup Sara , O’Dell Denise R. , Kleinschmidt Lina , Elliott Jim M. , Jayaraman Arun 
Published: October 2022

ObjectiveTo evaluate the combined effects of robotic exoskeleton and functional electrical stimulation (FES) training on muscle composition during over-ground gait training in persons with acute spinal cord injury (SCI).DesignRandomized crossover pilot study.SettingInpatient-rehabilitation Hospital.ParticipantsSix individuals with acute SCI.InterventionParticipants were randomized to either receive training with the Ekso® Bionics exoskeleton combined with FES in addition to standard-of-care or standard-of-care alone.Outcome measuresThe main outcome measures for the study were quantified using magnetic resonance imaging (MRI), specifically, lower extremity muscle volume and intramuscular adipose tissue (IMAT). Static balance and fall risk were assessed using the Berg Balance Scale.ResultsSignificant improvements were observed in muscle volume in the exoskeleton intervention group when compared to only standard-of-care (p &lt; 0.001). There was no significant difference between the groups in IMAT even though the intervention group saw a reduction in IMAT that trended towards statistical significance (p = 0.07). Static balance improved in both groups, with greater improvements seen in the intervention group.ConclusionsEarly intervention with robotic exoskeleton may contribute to improved muscle function measured using MRI in individuals with acute SCI.
OLIF versus MI-TLIF for patients with degenerative lumbar disease: Is one procedure superior to the other? A systematic review and meta-analysis
Authors: Wang Jianqiang , Liu Jingwei , Hai Yong , Zhang Yiqi , Zhou Lijin 
Published: October 2022

PurposeTo compare the effectiveness and safety of oblique lateral interbody fusion (OLIF) and minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) for degenerative lumbar disease.MethodsWe searched relevant studies in Embase, PubMed, Cochrane, and Web of Science databases comprehensively from inception to March 2022. The data were extracted from included studies, including operation indications, radiographic parameters, and clinical outcomes. Random or fixed-effects models were used in all meta-analyses according to the between-study heterogeneity.ResultsIn total, 30 studies, including 2,125 patients, were included in this meta-analysis. Our study found similar disk height, length of hospital stay, visual analog scale (VAS), and Oswestry disability index(ODI) between the two groups. However, the OLIF showed an advantage in restoring lumbar lordotic angle compared with MI-TLIF, with the pooled mean change of 17.73° and 2.61°, respectively. Additionally, the operative time and blood loss in the OLIF group appeared to be less compared with the MI-TLIF group. Regarding complications, the rates of the two groups were similar (OLIF 14.0% vs. MI-TLIF 10.0%), but the major complications that occurred in these two procedures differed significantly.ConclusionThe results of disk height, length of hospital stay, VAS, and ODI between the OLIF and MI-TLIF groups were similar. And the OLIF was superior in restoring lumbar lordotic angle, operative time, and blood loss. However, the OLIF group's complication rate was higher, although not significantly, than that in the MI-TLIF group.
Spillover Effect of the Nigerian “Free Primary Education” Programme Beyond the Border in Benin
Authors: Ogoutchoro Thierry , Bankole Fredo , Koumassa Bonou Leonie 
Published: October 2022

This Insight Note collects data from eastern Benin and aims to test the indirect spillover impacts of Nigeria’s Free Primary Education (FPE) programme on educational attainment, educational aspiration, and other life outcomes for children of school age at the time of the programme (1955).
TikTok: possibilidades de gestos críticos no ambiente virtual
Authors: Pereira Sônia Virginia Martins , Da Silva Everton Henrique Souza 
Published: October 2022

Ao navegarem nos espaços digitais, os sujeitos não recebem passivamente as informações. Eles têm, com considerável facilidade, o papel de escrileitor, conforme proposto por Paveau (2021) - leem e escrevem sobre o que está em circulação. Tal conjuntura permite a determinados teóricos defenderem a indissociabilidade entre as ações sociais do homem e a máquina atualmente. Por essa via, diversificadas plataformas populares, como o TikTok, mídia social chinesa, permitem, com seus recursos tecnológicos, a criação e circulação de práticas de linguagens que fomentam o debate de diversos temas e marcam posições ideológicas, num percurso de escrileitura. À vista disso, esta pesquisa objetiva refletir de que modo os discursos presentes nesse ambiente virtual instigam e contribuem para (des)construção de posicionamentos ideológicos, em cadeias discursivas. Sendo assim, nos apoiando numa fundamentação teórica composta por noções da análise dialógica do discurso, análise do discurso digital e da perspectiva de letramento crítico, analisamos posicionamentos em processos enunciativo-discursivos de postagens sobre dois temas recorrentes e seus comentários. A partir disso, compreendemos que, ao se constituir em arena discursiva, o TikTok corrobora para discursos performativos acerca de fatos e temas sociais, o que abre espaço para que interlocutores, em seus papéis ativos-responsivos, efetuem o processo de letramento crítico para ratificação e refutação de ideias, um traço do escrileitor, em seus movimentos enunciativos multissemióticos.
Hubungan pola asuh pemberian makan dan skor keragaman pangan dengan kejadian stunting pada balita usia 24–59 bulan
Authors: Suryawan Aisha Excelia , Ningtyias Farida Wahyu , Hidayati Manik Nur 
Published: October 2022

Latar Belakang: Stunting merupakan kegagalan tumbuh kembang anak yang diakibatkan kurangnya asupan zat gizi kronis dalam periode waktu yang panjang. Salah satu dari empat penyebab utama stunting adalah masalah penerapan pola asuh orang tua yang salah. Skor keragaman pangan dapat dijadikan sebagai acuan untuk menentukan kualitas makanan yang dikonsumsi oleh balita. Berdasarkan data Riskesdas tahun 2018, prevalensi stunting di wilayah Kabupaten Lumajang sebesar 34,01%. Kejadian stunting tertinggi pada tahun 2019 dan 2020 berada di Wilayah Kerja Puskesmas Klakah. Tujuan: Menganalisis hubungan pola asuh pemberian makan dan skor keragaman pangan dengan kejadian stunting pada balita usia 24–59 bulan di wilayah kerja Puskesmas Klakah. Metode: Penelitian ini menggunakan desain cross sectional yang dilakukan pada bulan Agustus tahun 2021. Populasi dalam penelitian ini adalah seluruh anak balita berusia 24–59 bulan yang tinggal di wilayah kerja Puskesmas Klakah, Kecamatan Klakah dengan besar sampel sebanyak 43 orang. Pengambilan sampel dilakukan dengan teknik cluster sampling. Variabel yang diteliti adalah pola asuh pemberian makan dan skor keragaman pangan. Pengambilan data menggunakan pengukuran antropometri, kuesioner pola asuh pemberian makan, dan kuesioner Individual Dietary Diversity Score (IDDS). Hasil: Pola asuh pemberian makan tidak berhubungan dengan kejadian stunting (p=0,127) dan skor keragaman pangan berhubungan dengan kejadian stunting (p=0,027; OR=5,143). Kesimpulan: Tidak terdapat hubungan antara pola asuh pemberian makan dengan kejadian stunting pada balita usia 24–59 bulan di wilayah kerja Puskesmas Klakah dan terdapat hubungan antara skor keragaman pangan dengan kejadian stunting pada balita usia 24–59 bulan di wilayah kerja Puskesmas Klakah.
Modifikasi resep hidangan pada menu diet tinggi kalori dan tinggi protein untuk pasien terinfeksi virus Covid-19 di rumah sakit
Authors: Sitasari Almira , Sari Tjarono , Kunti Laras Tri 
Published: October 2022

Latar Belakang: Tingkat kepuasan pasien yang rendah berdampak pasien tidak menghabiskan makanan. Sisa makanan pada hidangan untuk pasien Covid-19 adalah hidangan hewani berbasis ikan. Fish spinach termasuk hidangan yang memiliki sisa makanan tinggi di salah satu Rumah Sakit Rujukan Covid-19. Adanya pengembangan resep diharapkan dapat meningkatkan asupan protein dan menekan sisa makanan pasien. Tujuan: Menganalisis perbedaan daya terima pasien terinfeksi Covid-19 antara hidangan pada resep standar dan resep pengembangan lauk hewani ikan pada Rumah Sakit Rujukan Covid-19 di Yogyakarta. Metode: Penelitian eksperimental semu dengan rancangan one grup pretest-posttest design di salah satu Rumah Sakit Rujukan Covid-19 di Yogyakarta pada April 2021. Panelis penelitian merupakan semua pasien Covid-19 di Rumah Sakit Rujukan Covid-19. Peneliti melibatkan 20 pasien sebagai panelis. Penentuan tingkat kesukaan dengan metode hedonic test sedangkan daya terima diamati berdasarkan sisa makanan menggunakan taksiran visual comstock skala 6 poin. Hasil: Ada perbedaan yang signifikan antara hidangan standar dan hidangan modifikasi terhadap tingkat kesukaan warna (p=0,000), aroma (p=0,000), rasa (p=0,000), tekstur (p=0,002), penampilan (p=0,000) dan daya terima pasien Covid-19 (p=0,000). Kesimpulan: Hidangan modifikasi lauk hewani ikan dengan sisa makanan tinggi dapat meningkatkan daya terima dan mengurangi sisa makanan.
Robot End-effector for Fabric Folding
Authors: Seino Akira , Terayama Junya , Tokuda Fuyuki , Kobayashi Akinari , Kosuge Kazuhiro 
Published: October 2022

<p>In this paper, we propose a robot end-effector for fabric folding of a fabric part of a garment along a straight line. In the garment production process, some of the edges of fabric parts of a garment need to be folded before sewing. Conventional automated folding system has a fixture designed for each folding fabric part and operation. The fixture is not universal and needs to be redesigned when the shape of the folded fabric part changes. In this paper, we consider performing fabric folding without using a fixture. We propose a concept of a robot end-effector for fabric folding of a fabric part along a straight fold line and develop a prototype of an end-effector referred to as“ F-FOLD ”(Free-form FOLDing). Folding of the edge of a fabric part is achieved by moving FFOLD along the desired straight fold line. Experimental results illustrate how F-FOLD works to fold a fabric part along a straight line.</p>
<p><br></p>
<p> *The complete version of this preprint paper is published in IEEE/ASME (AIM) International Conference on Advanced Intelligent Mechatronics . Please refer to "https://ieeexplore.ieee.org/document/10196184". </p>
Parkinson’s Disease Diagnosis with Gait Characteristics Extracted Using Wavelet Transforms
Authors: Vimalajeewa Dixon , McDonald Ethan , Tung Megan , Vidakovic Brani 
Published: October 2022

<p>The objective of this study is to propose a methodology for early detection of Parkinson's disease based on gait patterns. A set of novel features are developed based on self-similar, correlation, and compressibility properties extracted by multiscale features of gait data in the wavelet domain. The dataset used in this study is available in the physionet repository. This study considers only the VGRF data collected from subjects while walking at their normal pace for 2 minutes on a flat surface. </p>
SIGNATURE RECOGNITION AND FORGERY DETECTION
Authors: R Anagha , Kumar G Chandan 
Published: October 2022

<p>Every person has a unique signature used mainly for personal identification and verification of essential documents or legal transactions. There are two kinds of signature verification: static and dynamic. Static(offline) verification is verifying an electronic or paper signature after it has been made. In contrast, dynamic(online) verification occurs as a person creates their signature on a digital tablet or a similar device. </p>
<p>In today’s world, offline signatures play an important role. Offline signature verification and forgery detection is a challenging field with many critical issues. Signature forgery drives cooperates and business organizations to substantial financial loss and affects their security reputation. Fraud can be mainly seen in Banks, which involve important documents, legal paper works, and Government policies (LIC) that could pose a threat and be viable to forgery and its implications.</p>
<p>So, there is a need for a system that can distinguish between genuine and forged signatures to avoid the chances of theft or fraud. Hence, we aim to create an intelligent model that gets trained with the real signature data sets and can detect a forged signature based on the available forged signature data sets using the Support Vector Machine (SVM) and K – Means algorithm. The proposed system achieves an accuracy of 95.83% for forgery detection.</p>
PENINGKATAN HASIL BELAJAR BOLA VOLI MENGGUNAKAN METODE PEMBELAJARAN PEER TEACHING
Authors: Candra Arya , Mislan Mislan 
Published: October 2022

Tujuan dari penelitian ini adalah untuk meningkatkan hasil belajar bola voli pada siswa kelas V SDN 4 Sumberberas. Jenis penelitian ini adalah Penelitian Tindakan Kelas (action research) dengan menggunakan 4 tahapan yaitu perencanaan, pelaksanaan, observasi dan refleksi. Penentuan responden dengan menggunakan teknik purposive sampling yaitu keseluruhan siswa kelas V b yang berjumlah 12 Siswa. Proses pengumpulan data dengan menggunakan lembar pengamatan saat proses pembelajaran, dan setelah proses pembelajaran. Lembar pengamatan yang di maksud mencakup nilai psikomotor, afektif, dan kognitif siswa mengenai teknik dasar servis dan smash bola voli. Hasil penelitian menunjukkan metode pembelajaran peer teaching yang diterapkanpada siswa kelas V b SDN 4 Sumberberas dapat meningkatkan hasil belajarsiswa dalam mata pelajaran pendidikan jasmani pada materi bola voli yaituteknik dasar smash, servis atas, dan servis bawah. pada setiap siklus telah mengalami perubahan nilai yang dapat dikatan baik (tuntas) dengan masing-masing nilai akhir atau rata-rata pada siklus 2 di teknik dasar smash yaitu 79,62 lalu teknik dasar servis atas yaitu 80,59 dan teknik servis bawah yaitu 81,23.
Pengaruh Latihan Rope Jump Dan Jump To Stairs Dengan Metode Interval Training Terhadap Power Tungkai Bola Voli Di Klub Mutiara Muda Jeketro
Authors: Kristiawan Novan Rio 
Published: October 2022

Abstrak:
Novan Rio Kristiawan. “Pengaruh Latihan Rope Jump Dan Jump To Stairs Dengan Metode Interval Training Terhadap Power Tungkai Bola Voli Di Klub Mutiara Muda Jeketro”. Program Studi Pendidikan Jasmani Kesehatan dan Rekreasi. Fakultas Pendidikan Ilmu Pengetahuan Sosial dan Keolahragaan Universitas PGRI Semarang 2020.
Latar belakang penelitian ini adalah pada saat observasi di klub mutiara muda jeketro banyak pemain yang kesulitan dalam melakukan smash karna tidak memiliki vertical jump yang tinggi. Tujuan penelitian ini adalah untuk mengembangkan model latihan rope jump danjump to stairs dengan metode interval training agar dapat dijadikan alternatif dalam latihan untuk meningkatkan vertical jump.
Desain penelitian ini adalah experiment dengan desain penelitian yang digunakan adalah “two groups pretest-posttest design”.
Hasil dari data penelitian menunjukkan bahwa ada pengaruh latihan Rope Jump terhadap vertical jump atlet bola voli putra Mutiara Muda Jeketro usia 14-17 tahun dengan t hitung (-3,073) > t tabel (2,26216), dan nilai signifikansi p (0,013) < dari 0,05, dengan kenaikan presentase sebesar 5,16% atau 1,65 cm. 2.Ada pengaruh latihan Jump to Stairs terhadap vertical jump atlet bola voli putra Mutiara Muda Jeketro usia 14-17 tahun dengan t hitung (-3,674) > t tabel (2,26216), dan nilai p (0,005) < dari 0,05, hasil tersebut menunjukkan bahwa nilai t hitung lebih besar dari pada t tabel. Dengan peningkatan sebesar 1,98% atau 1,2 cm.
Berdasarkan hasil analisis data, pengujian hasil penelitian, dan pembahasan, dapat diambil kesimpulan, yaitu: Latihan Rope Jump lebih baik untuk meningkatkan verticaljump atlet bola voli Mutiara Muda Jeketro usia 14-17 tahun, dengan thitung(-3,073) > ttabel (2,26216), dan nilai p (0,013) < dari (0,05). Dengan selisih perbedaan5,16% atau 1,65 cm lebih baik rope jump dibandingkan dengan jump to stairs.
Kata kunci:Rope jump, jump to stairs, kemampuan Vertical Jump, Interval Training.
Hubungan Antara Kekuatan Otot Tungkai Kekuatan Otot Lengan dan Keseimbangan Tubuh Terhadap Hasil Ketepatan Lemparan Pointing Jarak 6 Meter Pada Ukm Petanque Upgris
Authors: Hidayah Erika Wahyu 
Published: October 2022

Tujuan dari penelitian ini untuk mengetahu hubungan antara kekuatan otot tungkai kekuatan otot lengan dan keseimbangan tubuh pada hasil ketepatan lemparan pointing jarak 6 meter dengan teknik posisi jongkok bagi para anggota UKM petanqu UPGRIS. lemparan pointing pada olahraga petanque yaitu suatu upaya seseorang atau tim dalam menghantarkan bola untuk mendekati target. Penelitia ini digunakan untuk mengembangkan olahraga petanque di Ukm petanque UPGRIS. Metode yang digunakan dalam penelitian menggunakan jenis penelitiana kuantitatif dengan teknik korelasional dengan metode pearson Correlation. Metode yang digunakan untuk analisis korelasi menggunakan pearson product moment. Hasil penelitian menujukan Rhitung (0,840) > Rtabel (0,6319) dan nilai Sig. (0,005) < α (0,05) yang berarti terdapat hubungan yang signifikan antara kekuatan otot tungkai dengan hasil ketepatan lemparan pointing. Dimana besarnya nilai Korelasi yaitu 0,805 termasuk dalam kategori korelasi kuat. Diperoleh nilai Rhitung (0,755) > Rtabel (0,6319) dan nilai Sig. (0,012) < α (0,05) berarti terdapat hubungan yang signifikan antara kekuatan otot lengan dengan hasil ketepatan lemparan pointing. Dimana besarnya nilai Korelasi yaitu 0,755 termasuk dalam kategori korelasi kuat. Diperoleh nilai Rhitung (0,755) > Rtabel (0,635) dan nilai Sig. (0,049) < α (0,05) berarti terdapat hubungan yang signifikan antara keseimbangan tubuh dengan hasil ketepatan lemparan pointing. Dimana besarnya nilai Korelasi yaitu 0,635 termasuk dalam kategori korelasi kuat. Maka dapat disimpulkan bahwa kekuatan otot tungkai kekuatan otot lengan dan keseimbangan tubuh mempunyai hubungan yang signifikan yang kuat terhadap hasil ketepatan lemparan pointing jarak 6 meter olahraga petanque
Kata kunci: kekuatan otot tungkai, kekuatan otot lengan, keseimbangan tubuh dan ketepatan lemparan pointing jarak 6 meter.
Pengaruh Latihan Push Up Terhadap Hasil Passing Chest Pass Pada Ekstrakurikuler Bola Basket
Authors: Fitrah Fathul , Bayu Wahyu Indra , Iyakrus Iyakrus 
Published: October 2022

Penelitian bertujuan untuk mengetahui pengaruh latihan push up terhadap hasil passing chest pass pada ekstrakurikuler bola basket. Metode penelitian ini adalah penelitian eksperimen. Populasi penelitian adalah siswa ekstrakurikuler bola basket di SMP Negeri 3 Sekayu. Sampel penelitian ini berjumlah 60 orang yang dibagi menjadi 2 kelompok yaitu, kelompok eksperimen dan kelompok kontrol. Instrumen penelitian yang digunakan adalah tes passing chest pass. Perlakuan pada penelitian ini berupa latihan push up diberikan selama 6 minggu dengan frekuensi latihan selama 3 kali dalam seminggu. Uji efektivitas menggunakan metode eksperimen dengan hasil “uji t” signifikan ɑ = 0,05 didapat thitung = (8,68) sedangkan ttabel (1,67), maka thitung > ttabel berate Ha dapat diterima. Sedangkan Ho ditolak. Berdasarkan hasil penelitian dapat disimpulkan latihan push up memiliki pengaruh terhadap peningkatan kemampuan passing chest pass. Implikasi hasil penelitian yakni latihan push up dapat digunakan sebagai salah jenis latihan untuk kemampuan passing chest pass.