bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENANAMAN KEMANDIRIAN ANAK USIA 4-5 TAHUN BERBASIS METODE PROYEK DI PAUD VIDYA KARUNA KOTA DENPASAR
Authors: Sany Silvia Nina , Suyanta I Wayan , Lestiawati I Made 
Published: November 2022

Masa pandemi yang berkepanjangan, memaksa anak-anak untuk kehilangan masa pembelajaran mereka di sekolah. Terdapat banyak kendala terutama pembelajaran pada anak usia dini. Guru diharapkan mampu memberikan bentuk pembelajaran yang nyaman dan menyenangkan, salah satunya adalah pembelajaran metode berbasis proyek. Dengan menerapkan pendekatan berbasis metode proyek di sekolah PAUD Vidya Karuna Denpasar, anak mendapat pengalaman belajar dengan bekerja sama, berbagi tugas dan tanggung-jawab yang dilakukan secara terintegrasi untuk mencapai tujuan akhir yang dimiliki bersama. Sesuai dengan teori John Dewey (Learning by Doing), anak-anak memahami materi ketika anak sudah mencoba melakukan kegiatan dan mencari tahu pemecahan dari suatu masalah. Fokus dari penelitian ini adalah penanaman kemandirian anak berbasis metode proyek. Jenis penelitian ini adalah penelitian kualitatif deskriptif dengan teknik pengumpulan data observasi, wawancara, dan dokumentasi. Teknik analisis data yang digunakan adalah model Miles and Hubberman yang terdiri dari tiga alur diantaranya, reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukkan penanaman kemandirian anak melalui pembelajaran metode berbasis proyek ini terjadi peningkatan sebesar 40% dari awal observasi. Sebanyak 86% anak-anak usia 4-5 tahun telah mandiri sesuai dengan indikator instrumen kemandirian anak. Pembelajaran berbasis metode proyek juga dapat meningkatkan kognitif dan social-emosi anak-anak.

Kata Kunci: Penanaman Kemandirian Anak, Metode Proyek
MECANISMOS DE EXPRESSÃO DE RESISTÊNCIA AOS ANTIBIÓTICOS E SAÚDE PÚBLICA
Authors: Dalmolin Jaqueline , Nakano Robson Luiz , Marcusso Paulo Fernandes , Boleta-Ceranto Daniela de Cássia Faglioni , Cogo Juliana , Melo Patricia Gizeli Brassalli de , Zardeto Giuliana 
Published: November 2022

Com o avanço da medicina e o aumento do uso de antimicrobianos, a resistência microbiana vem se tornando um problema sério na saúde pública. Para que uma bactéria se torne resistente, são necessários vários fatores, entre eles, o uso indiscriminado e prolongado de antimicrobianos e as resistências intrínsecas e adquiridas. Nesse contexto, o objetivo do trabalho foi explorar os mecanismos de ação dos antimicrobianos, de resistência e a sua importância na saúde pública. Foram utilizadas para a presente pesquisa, as bases de dados Pubmed, Google acadêmico e Scielo. Segundo a Organização Mundial da Saúde define-se resistência ao antibiótico quando o mesmo não produz mais efeito. A inserção cada vez mais frequente de antimicrobianos favorece a resistência, onde provocam uma pressão seletiva sobre os microrganismos, tornando-os resistentes a diversas drogas. O uso indiscriminado de antimicrobianos é o principal fator de resistência microbiana, assim como o uso de antimicrobianos sem exame de cultura e teste de sensibilidade. Neste sentido, conclui-se que é de suma importância a atualização de protocolos que contenham os mecanismos de resistência bacteriana a fim de minimizar o uso indiscriminado de antimicrobianos, assim como capacitar os profissionais da saúde para este problema na saúde pública.
Análise das características da Hipertermia Maligna: uma revisão de literatura
Authors: Azevedo Pedro Leite Cabral , Siqueira Emílio Conceição de 
Published: November 2022

Objetivo: Analisar as características da Hipertermia Maligna (HM). Revisão bibliográfica: A HM é uma rara emergência anestésica. Consiste em uma doença farmacogenética dos músculos esqueléticos com risco de vida que se apresenta como uma resposta hipermetabólica exagerada a agentes anestésicos voláteis e relaxantes musculares despolarizantes. Os sinais clínicos de hipermetabolismo, incluindo hipercapnia, taquicardia e rigidez muscular generalizada, seguida de hipertermia, acidose metabólica e respiratória, hipercalemia e resultante arritmia ou parada cardíaca. Essa reação ocorre em indivíduos com certa predisposição genética. Como os pacientes suscetíveis não apresentam alterações fenotípicas antes da anestesia, é impossível diagnosticá-los antes da exposição ou antes da realização de exames específicos. Considerações finais: A hipertermia maligna é um transtorno farmacogenético raro, possivelmente letal, do músculo esquelético, que envolve a liberação de íons cálcio do retículo sarcoplasmático que ocorre em indivíduos geneticamente suscetíveis que têm uma resposta hipermetabólica a certos anestésicos voláteis (como halotano, isoflurano, sevoflurano, desflurano, enflurano), isoladamente ou em conjunto com um relaxante muscular despolarizante (especificamente, succinilcolina). O Dantroleno é o medicamento de escolha nesses casos, devendo estar prontamente disponível na sala de cirurgia.
TYPOLOGY OF INTERTEXTUAL CONNECTIONS IN POSTMODERN DISCOURSE: TEXTUAL, CONTEXTUAL AND METATEXTUAL INFLUENCES
Authors: Hurbаnskа Svitlаnа O. 
Published: November 2022

Artistic texts as products of individual authorial creative work, formed as a result of interaction with previous texts – with literary and cultural heritage, require a systematic linguistic study. They enter into a dialogue with the semiosphere both at the moment of generation, and in the process of their reading, perception and understanding. The organization of the artistic text structure occurs with the help of intertextual connections in conceptual and linguistic forms. Thus, the study and understanding of the artistic text involves the research of the conceptual and language picture of the writer’s world, the linguistic representation of intertextual connections. In postmodern artistic texts, pretexts are recoded, instead, intertextual forms, harmoniously combined and mutually rethought, create the idiostyle profile. Each writer has his own vocabulary, favorite themes and images that define internal cycles in his creative work, which cannot be contained within precise chronological boundaries. Currently, there is a revival of attention to the scientific study of intertextual relations specifics in postmodern discourse, as well as a general gravity tendency of the humanitarian paradigm of knowledge to the cognitive and communicative analysis of textual communication, in particular, the influence of postmodernism on modern post-industrial communicative culture, which finds expression in the artistic speech aesthetics. The use of the concept “the author’s consciousness” is necessary in the study of the communicative, cognitive, informative and emotional integrity of the text. The modeling of the writer’s consciousness with the help of intertextual connections with other texts is based on the ideas of cognitive linguistics.
Mandadang: Kearifan Lokal Masyarakat Batak Untuk Perempuan Pasca Melahirkan
Authors: Muary Rholand , Sembiring Feriel Amelia 
Published: November 2022

Abstract : Indonesia is a country that is diverse or diverse in terms of ethnicity, nation and religion. This diversity of tribes, nations and religions will affect the number of cultural variations. One of the customs of the Batak tribe in Simalungun Regency is the Mandadang tradition. Subjects in research are individuals, objects or organisms needed in collecting research data. In this study using qualitative methods, data collection methods with participatory observation, and in-depth interviews. The results how to do mandadang by bringing the mother's body closer to firewood on a cooking stove or bonfire 1-2 m apart. The Batak people do this because some of the areas they live in have low temperatures and the large of blood they secrete causes the body to become cold. This culture is carried out like an incubator but an ancient version or an economical ancestor and uses human resources. Mandadang is carried out for 1 month, because the development of the Age is reduced to 1 week. Mandadang activities also cause puffs of smoke in the room and are at risk of respiratory problems and dry skin. Abstrak: Indonesia merupakan negara yang majemuk atau beraneka ragam suku, bangsa dan agamanya. Keanekaragaman suku, bangsa dan agama ini berpengaruh akan banyaknya variasi budaya. Salah satunya adat istiadat pada suku Batak di Kabupaten Simalungun yaitu tradisi mandadang. Penelitian ini bertujuan untuk mendeskripsikan proses rangkaian tradisi mandadang sebagai cara untuk mengeringkan atau penghangatan setelah melahirkan. Subjek dalam penelitian adalah individu, benda atau organisme yang dibutuhkan dalam pengumpulan data penelitian. Dalam penelitian ini menggunakan metode kualitatif, cara pengumpulan data dengan observasi partisipasi, dan wawancara mendalam. Hasil penelitian menunjukkan cara melakukan mandadang dengan mendekatkan badan ibu dengan kayu bakar pada tungku masak atau api unggun berjarak 1-2 m. Masyarakat batak melakukan ini karena, beberapa wilayah yang ditempatinya memiliki suhu rendah serta banyaknya darah yang dikeluarkan menyebabkan tubuh menjadi dingin. Budaya ini dilakukan menyerupai inkubator tetapi versi zaman dulu namun lebih ekonomis serta dipercaya dapat mempercepat kesembuhan perempuan pasca melahirkan yang sudah turun temurun dipraktikkan. Mandadang dilakukan selama 1 bulan, karena perkembangan zaman berkurang menjadi 1 minggu.
Koeksistensi Perempuan Penopang Kehidupan di Pedesaan Demuk
Authors: Meliza Richa , Chalid Ibrahim , Ilham Iromi 
Published: November 2022

Abstract: The phenomenon of the women life who support life in rural areas has reciprocity and adjustment in people's lives in terms of the domestic and public spheres. This must be done because of the weak point of view of the community on the culture and habits of women who are in these two domains. The purpose of this paper is to describe the lives of women who support life in rural areas that are different from women in urban areas, both from the domestic and public realms. This study used qualitative research methods. The data collection process was carried out through live In, observation, in-depth interviews (indept interviews), and the use of documentation studies. Women in rural areas have a stronger survival in continuing their lives, especially economic problems, although women's lives are limited in all access, they have a goal in the welfare of their families and communities by living on land as farmers. Village culture and customs that are still thick are not an obstacle in terms of working, if they are still in the realm of rural culture that is polite, respectful, please help and others. So it is not a problem for women in rural areas to work in both domestic and public spheres.Abtract: Fenomena kehidupan perempuan penopang kehidupan di daerah pedesaan memiliki timbal balik dan penyesuaian di dalam kehidupan masyarakat dari segi ranah domestik dan publik. Hal ini harus dilakukan bersebab lemahnya sudut pandang masyarakat terhadap budaya dan kebiasaan perempuan yang berada dalam kedua ranah tersebut. Tujuan dalam tulisan ini adalah untuk menggambarkan kehidupan terkait perempuan penopang kehidupan di daerah pedesaan yang berbeda dengan perempuan di daerah perkotaan, baik dari ranah domestik maupun publik. Penelitian ini menggunakan Metode penelitian kualitatif. Proses pengumpulan data dilakukan melalui Live In, observasi, wawancara mendalam (indept interview), dan penggunaan studi dokumentasi. Perempuan di daerah pedesaan mempunyai ketahanan hidup yang lebih kuat dalam meneruskan kehidupan terutama masalah ekonomi walaupun kehidupan para perempuan terbatas dalam segala akses, mereka memiliki tujuan dalam menyejahterakan keluarga dan masyarakat dengan cara bertanah hidup sebagai petani. Budaya dan adat istiadat pedesaan yang masih kental tidak menjadi kendala dalam hal bekerja, jika masih dalam ranah sesuai dengan budaya pedesaan yang santun, menghargai, tolong menolong dan lainnya. Sehingga tidak menjadi suatu permasalahan bagi perempuan di daerah pedesaan untuk bekerja dalam kedua ranah domestik dan publik.
AKTIVITAS ANTIHIPERURISEMIA EKSTRAK KULIT BUAH PISANG MAS (Musa acuminata Colla) TERHADAP MENCIT JANTAN GALUR BALB-C
Authors: Apriliyanti Ika Putri 
Published: November 2022

Kulit buah pisang mas (Musa acuminata Colla) merupakan limbah dari pengolahan buah pisang yang dapat dimanfaatkan sebagai bahan dari alam untuk pengobatan tradisional seperti penurun kadar Asam Urat. Tujuan penelitian ini adalah mengamati aktivitas antihiperurisemia dari ekstrak kulit buah pisang mas terhadap mencit jantan balb-c. Untuk pengujian aktivitas antihiperurisemia dari ekstrak, sebanyak 25 mencit jantan galur balb-c dibagi menjadi 5 kelompok. semua kelompok dijadikan hiperurisemia dengan induksi jus hati ayam selama 18 hari dan pemberian Kalium Oksonat secara intra peritoneal pada hari ke-9 sebelum pengambilan darah pra-perlakuan. Selama masa perlakuan untuk kelompok negatif diberikan CMC Na 0,5%, kelompok positif diberikan Allopurinol 0,26 mg/20g BB dan 3 kelompok perlakuan diberikan ekstrak dengan dosis 2,5 mg/20g BB mencit, 5 mg/20g BB mencit, 10 mg/20g BB mencit. Pada hari ke-19 dilakukan pengambilan darah untuk hasil pasca-perlakuan dan data pengukuran untuk kadar Asam Urat dilakukan dengan metode enzimatik menggunakan Photometer Biolyzer 100 panjang gelombang 546 nm. Hasil pengukuran kadar Asam Urat serum menyatakan ekstrak kulit buah pisang dengan dosis 2,5 mg/20g BB, 5 mg/20g BB, 10 mg/20g BB dapat menurunkan kadar Asam Urat. Ketiga dosis terdapat perbedaan bermakna dengan kontrol positif maupun negatif (sig.<0,05). Ketiga dosis ekstrak juga tidak menunjukkan perbedaan yang bermakna dari masing-masing dosis namun dosis 2,5 mg/20g BB lebih efektif dalam menurunkan kadar Asam Urat yang mencapai 44,69 %. Penelitian ini menyimpulkan bahwa ekstrak kulit buah pisang mas (Musa acuminata Colla) mempunyai aktivitas antihiperurisemia.
PENGARUH PENDIDIKAN TUMBUH KEMBANG ANAK ASIA 6-36 BULAN MENGGUNAKAN BOOKLET TERHADAP PENGETAHUAN DAN KEMAMPUAN STIMULASI PERKEMBANGAN PADA IBU DI WILAYAH KERJA PUSKESMAS MRICAN KOTA KEDIRI TAHUN 2019
Authors: Khofi Khofidhotur Rofiah 
Published: November 2022

ABSTRAK Latar Belakang: Masa anak-anak adalah masa keemasan bagi perkembangan anak (golden age) yang dalam tindakannya sering meniru orang tua. Namun, orang tua masih memiliki pengetahuan dan kemampuan stimulasi perkembangan yang kurang, dimana 90% ibu tidak mengetahui tentang stimulasi perkembangan. Tujuan penelitian ini adalah untuk membuktikan pengaruh pendidikan tumbuh kembang anak usia 6-36 bulan melalui media booklet terhadap pengetahuan dan kemampuan stimulasi perkembangan. Metode: Desain penelitian ini adalah quasy experimentaldengan rancangan pretest posttest control group designdengan kelompok kontrol menggunakan media powerpoint. Populasi dari penelitian ini adalah ibu yang mempunyai anak gangguanstimulasiperkembanganusia 6-36 bulan di wilayah Kerja PuskesmasMricanKota Kediri tahun 2019 yang berjumlah 38orang. Pengambilan sampel dalam penelitian ini dilakukan dengan purposive sampling, sehingga didapatkan 36 responden yang terdiri dari 18 orang kelompok eksperimen dan 18 orang kelompok kontrol. Instrumen Penelitian adalah booklet,powerpoint, kuesioner dan lembar observasi. Analisis data berupa analisis deskriptif, prasyarat analisis menggunakan uji normalitas Saphiro Wilk dan Homogenitas, uji hipotesis menggunakan paired T test, independent T test, dan Uji Manova. Hasil penelitian: analisis Paired Sample T test pengetahuan menunjukkan bahwa nilai kelompok eksperimen menunjukkan bahwa nilai mean pretest 74,54, mean posttest89,58, dan signifikansi 0,000. Hasil uji Independent T Test pengetahuan didapatkan pvalue 0,031. Hasilanalisis Paired Sample T test kemampuan stimulasi menunjukkan bahwa nilai kelompok eksperimen menunjukkan bahwa nilai mean pretest 20,56, mean posttest 24,33, dan signifikansi 0,000. Hasil uji Independent T Test kemampuan stimulasi didapatkan pvalue 0,008. Hasil uji Manovavariable luar sumber informasi pengetahuan menunjukkan bahwa nilai pvalue 0,019 dan Partial Eta Squared 0,282. Hasil Uji Manova efektivitas booklet dan Powerpoint menunjukkan bahwa booklet dapat meningkatkan pengetahuan tumbuh kembang sebesar 85,2% dan kemampuan stimulasi sebesar 71,4%, powerpoint dapat meningkatkan pengetahuan tumbuh kembang sebesar 78,9% dan kemampuan stimulasi sebesar 63,5%. Kesimpulan:Booklet pendidikan tumbuh kembang dapat mempengaruhi secara signifikan peningkatan pengetahuan dan kemampuan stimulasi perkembangan. Diharapkan booklet yang telah dikembangkan dapat digunakan oleh tenaga kesehatan khususnya bidan dalam melakukan pendidikan tumbuh kembang. Kata Kunci:booklet, pengetahuan, kemampuan, stimulasi perkembangan, tumbuh kembang
INVENTARISASI JENIS-JENIS ZINGIBERACEAE DI HUTAN TELAGAH TAMAN NASIONAL GUNUNG LEUSER KABUPATEN LANGKAT SUMATERA UTARA
Authors: Hutasuhut Melfa Aisyah 
Published: November 2022

<p>Zingiberaceae is one of perennial herbaceous plant that was unique to its rhizomes. This is because the Zingiberaceae contains evaporated oil or had an aromatic odor. This research was conducted in February to March 2018 in the Telagah Forest of Gunung Leuser National Park, Langkat Regency. This research used descriptive procedures with observation techniques. The result based on observations obtained 11 species of Zingiberaceae, with 7 Genus of Zingiberaceae. The <em>Globba</em> Genus has the most number of species, 4 species (<em>Globba nawawii</em> Ibrahim &amp; K. Larsen; <em>Globba paniculata</em> Valeton; <em>Globba patens</em> Miq; and <em>Globba pendula</em> Roxb.), <em>Etlingera</em> Genus <em>(Etlingera alatior</em> (Jack) R.M. Sm.; and <em>Etlingera littoralis</em> (J. Konig) Giseke), <em>Amomum</em> Genus <em>(Amomum ochreum</em> Ridl.), <em>Curcuma</em> Genus (Curcuma sp.), <em>Hedychium</em> Genus <em>(Hedychium coronarium</em> Koenig.), <em>Hornstedtia</em> Genus <em>(Hornstedtia tomentosa</em> (Blume) bakh.f.) and <em>Zingiber</em> Genus <em>(Zingiber multibracteata</em> Holtt).</p><p><strong>Keywords</strong>: Zingiberaceae. Rhizomes, Gunung Leuser National Park.</p>
STUDI ETNOBOTANI DAN AKTIVITAS FARMAKOLOGI EKSTRAK DAUN SIRSAK (Annona Muricata L.)
Authors: Rasyidah Rasyidah 
Published: November 2022

<p><em>Annona muricata</em> L. is a medicinal plant and claimed to be useful for human health. Study of ethnobotany about this plant need more research in order to find a range of pharmacological properties. Exploration of chemical constituents for soursop leaf extract is reported and contain numerous complex active phytochemicals. These secondary metabolite were important to explore more pharmacology activity. Leaf of <em>Annona muricata</em> L. had extracted and had been identified to has benefecial effects as anticancer, antioxidant, antiinflammatory, antihyperglicaemic, antifungal, and antibacterial. This review research emphasizes the systematic investigation of Annona muricata L. in pharmacology activity, which could be the impotent source for numerous human disorders. The result showed that 6 pharmacology activity from this leaves exctract which are anti-cancer, antioxidant, anti-inflammatory , antihyperglycemic, antifungal and antibacterial.</p><p><br /><strong>Keywords</strong>: soursop leaf, Annona muricata, pharmacology</p><p class="abstrak"> </p>
On the trace of permuting tri-derivations on rings
Authors: Yılmaz D. , Yazarlı H. 
Published: November 2022

In the paper we examined the some effects of derivation, trace of permuting tri-derivation and endomorphism on each other in prime and semiprime ring.Let $R$ be a $2,3$-torsion free prime ring and $F:R\times R\times R\rightarrow R$ be a permuting tri-derivation with trace $f$, $ d:R\rightarrow R$ be a derivation. In particular, the following assertions have been proved:1) if $[d(r),r]=f(r)$ for all $r\in R$, then $R$ is commutative or $d=0$ (Theorem 1);\
2) if $g:R\rightarrow R$ is an endomorphism such that $F(d(r),r,r)=g(r)$ for all $r\in R$, then $F=0$ or $d=0$ (Theorem 2);
3) if $F(d(r),r,r)=f(r)$ for all $r\in R$, then $(i)$ $F=0$ or $d=0$, $(ii)$ $d(r)\circ f(r)=0$ for all $r\in R$ (Theorem 3).
In the other hand, if there exist permuting tri-derivations $F_{1},F_{2}:R\times R\times R\rightarrow R$ such that $F_{1}(f_{2}(r),r,r)=f_{1}(r)$ for all $r\in R$, where $f_{1}$ and $%f_{2}$ are traces of $F_{1}$ and $F_{2}$, respectively, then $(i)$ $F_{1}=0$ or $F_{2}=0$, $(ii)$ $f_{1}(r)\circ f_{2}(r)=0$ for all $r\in R$ (Theorem 4).
Artificial intelligence in healthcare: Setting new algo RHYTHM in medicine
Authors: Ruby Dhar  , Kumar Arun , Subhradip Karmakar  
Published: November 2022

Artificial intelligence (AI) is a rapidly expanding avenue in science and is often used to describe the use of computers, big data mining, modeling, and network that may simulate intelligent behavior and critical thinking similar to a human being but at an exceedingly fast pace. What lies at the heart of AI are intelligent algorithms that drive the whole process integratively, imparting the decisive ability to machines. The artificial intelligence market is expected to grow at a rate of 39.4% by 2022-2028.
British mathematician Alan Turing’s 1950 paper “Computing Machinery and Intelligence " established AI's fundamental goal and vision. Fundamentally, AI is a branch of computer science that aims to answer Turing’s question of replicating human intelligence as machines.
Since AI research aims to make smarter algorithms evolve and emulate human-like functioning, the degree to which an AI system can replicate human capabilities is used to determine the types of AI.
The volume, magnitude, and complexity of data in healthcare mean that artificial intelligence (AI) will be increasingly applied and exploited, with several types of AI already being employed by researchers, clinicians, and data analysts. AI is a collective term, not just one technology, with an immediate relevance to healthcare. Few AI technologies of high importance to healthcare are:

Machine learning, Neural Networks, and Deep Learning
Natural Language Processing ( NLP)
Physical Robots
Rule-based expert systems

The AI-associated healthcare market is growing at an exponential pace and is expected to reach USD 6.6 billion by 2021.
Precision medicine initiatives can be divided into three types of clinical areas: complex algorithms, digital health applications, and “omics”-based tests.
Large genomic datasets and informatics related to demographic data or diagnostic reports are exploited by machine learning algorithms for prediction and prognosis. This is coupled with patient healthcare data, such as treatment protocols, treatment response, response to therapy, and health monitoring, with data input from clinicians, researchers, and the public domain. High throughput big data from population-based studies are used with machine learning algorithms to establish correlations, build predictive models, and provide customized treatment protocols. In Omics based era, data from genomics, proteomics, and metabolomics are exceedingly used to address and identify health-related problems in large study cohorts . This will provide opportunities for translation and transition from bench to bedside through precision medicine.