bluuebunny/crossref_metadata_2025_split huggingface dataset:
Applying multilayer analysis to morphological, structural, and functional brain networks to identify relevant dysfunction patterns
Authors: Casas-Roma Jordi , Martinez-Heras Eloy , Solé-Ribalta Albert , Solana Elisabeth , Lopez-Soley Elisabet , Vivó Francesc , Diaz-Hurtado Marcos , Alba-Arbalat Salut , Sepulveda Maria , Blanco Yolanda , Saiz Albert , Borge-Holthoefer Javier , Llufriu Sara , Prados Ferran 
Published: June 2022

Abstract
In recent years, research on network analysis applied to MRI data has advanced significantly. However, the majority of the studies are limited to single networks obtained from resting-state fMRI, diffusion MRI, or gray matter probability maps derived from T1 images. Although a limited number of previous studies have combined two of these networks, none have introduced a framework to combine morphological, structural, and functional brain connectivity networks. The aim of this study was to combine the morphological, structural, and functional information, thus defining a new multilayer network perspective. This has proved advantageous when jointly analyzing multiple types of relational data from the same objects simultaneously using graph- mining techniques. The main contribution of this research is the design, development, and validation of a framework that merges these three layers of information into one multilayer network that links and relates the integrity of white matter connections with gray matter probability maps and resting-state fMRI. To validate our framework, several metrics from graph theory are expanded and adapted to our specific domain characteristics. This proof of concept was applied to a cohort of people with multiple sclerosis, and results show that several brain regions with a synchronized connectivity deterioration could be identified.
Quantifying the Impact of Precipitation-Type Algorithm Selection on the Representation of Freezing Rain in an Ensemble of Regional Climate Model Simulations
Authors: McCray Christopher D. , Thériault Julie M. , Paquin Dominique , Bresson Émilie 
Published: June 2022

Abstract
Given their potentially severe impacts, understanding how freezing rain events may change as the climate changes is of great importance to stakeholders including electrical utility companies and local governments. Identification of freezing rain in climate models requires the use of precipitation-type algorithms, and differences between algorithms may lead to differences in the types of precipitation identified for a given thermodynamic profile. We explore the uncertainty associated with algorithm selection by applying four algorithms (Cantin and Bachand, Baldwin, Ramer, and Bourgouin) offline to an ensemble of simulations of the fifth-generation Canadian Regional Climate Model (CRCM5) at 0.22° grid spacing. First, we examine results for the CRCM5 driven by ERA-Interim reanalysis to analyze how well the algorithms reproduce the recent climatology of freezing rain and how results vary depending on algorithm parameters and the characteristics of available model output. We find that while the Ramer and Baldwin algorithms tend to be better correlated with observations than Cantin and Bachand or Bourgouin, their results are highly sensitive to algorithm parameters and to the number of pressure levels used. We also apply the algorithms to four CRCM5 simulations driven by different global climate models (GCMs) and find that the uncertainty associated with algorithm selection is generally similar to or greater than that associated with choice of driving GCM for the recent past climate. Our results provide guidance for future studies on freezing rain in climate simulations and demonstrate the importance of accounting for uncertainty between algorithms when identifying precipitation type from climate model output.

Significance Statement
Freezing rain events and ice storms can have major consequences, including power outages and dangerous road conditions. It is therefore important to understand how climate change might affect the frequency and severity of these events. One source of uncertainty in climate studies of these events is related to the choice of algorithm used to detect freezing rain in model output. We compare the frequency of freezing rain identified using four different algorithms and find sometimes large differences depending on the algorithm chosen over some regions. Our findings highlight the importance of taking this source of uncertainty into account and will provide researchers with guidance as to which algorithms are best suited for climate studies of freezing rain.
Shear Instabilities and Stratified Turbulence in an Estuarine Fluid Mud
Authors: Tu Junbiao , Fan Daidu , Sun Feixiang , Kaminski Alexis , Smyth William 
Published: June 2022

Abstract
This study presents field observations of fluid mud and the flow instabilities that result from the interaction between mud-induced density stratification and current shear. Data collected by shipborne and bottom-mounted instruments in a hyperturbid estuarine tidal channel reveal the details of turbulent sheared layers in the fluid mud that persist throughout the tidal cycle. Shear instabilities form during periods of intense shear and strong mud-induced stratification, particularly with gradient Richardson number smaller than or fluctuating around the critical value of 0.25. Turbulent mixing plays a significant role in the vertical entrainment of fine sediment over the tidal cycle. The vertical extent of the billows identified seen in the acoustic images is the basis for two useful parameterizations. First, the aspect ratio (billow height/wavelength) is indicative of the initial Richardson number that characterizes the shear flow from which the billows grew. Second, we describe a scaling for the turbulent dissipation rate ε that holds for both observed and simulated Kelvin–Helmholtz billows. Estimates for the present observations imply, however, that billows growing on a lutocline obey an altered scaling whose origin remains to be explained.
Ocean Surface Roughness from Satellite Observations and Spectrum Modeling of Wind Waves
Authors: Hwang Paul A. 
Published: June 2022

Abstract
Many wind wave spectrum models provide excellent wave height prediction given the input of wind speed and wave age. Their quantification of the surface roughness, on the other hand, varies considerably. The ocean surface roughness is generally represented by the mean square slope, and its direct measurement in open ocean remains a challenging task. Microwave remote sensing from space delivers ocean surface roughness information. Satellite platforms offer global coverage in a broad range of environmental conditions. This paper presents low-pass mean square slope (LPMSS) data obtained by spaceborne microwave altimeters and reflectometers operating at L, Ku, and Ka bands (about 1.6, 14, and 36 GHz). The LPMSS data represent the spectrally integrated ocean surface roughness with 11, 95, and 250 rad m−1 upper cutoff wavenumbers, and the maximum wind speeds are 80, 29, and 25 m s−1, respectively. A better understanding of the ocean surface roughness is important to the goal of improving wind wave spectrum modeling. The analysis presented in this paper shows that over two orders of magnitude of the wavenumber range (0.3–30 rad m−1), the spectral components follow a power function relating the dimensionless spectrum and the ratio between wind friction velocity and wave phase speed. The power function exponent is about 0.38, which is considerably smaller than unity as expected from the classical equilibrium spectrum function. It may suggest that wave breaking is not only an energy sink but also a source of roughness generation covering a wideband of wavelengths about 20 m and shorter.

Significance Statement
This paper presents low-pass mean square slope (LPMSS) data obtained by spaceborne microwave altimeters and reflectometers operating at L, Ku, and Ka bands (about 1.6, 14, and 36 GHz). The LPMSS data represent the spectrally integrated ocean surface roughness with 11, 95, and 250 rad m−1 upper cutoff wavenumbers, and the maximum wind speeds are 80, 29, and 25 m s−1, respectively. A better understanding of the ocean surface roughness is important to the goal of improving wind wave spectrum modeling that is critical to the investigation of air–sea interaction and ocean remote sensing. The analysis presented in this paper suggests that wave breaking is not only an energy sink but also a generation source of surface roughness covering a wide band of wavelengths about 20 m and shorter.
Adolescents’ social support networks and long-term psychosocial outcomes
Authors: Seok Deborah , Doom Jenalee R. 
Published: June 2022

The current study examined how adolescents’ social support networks are associated with long-term psychosocial outcomes (depressive symptoms and romantic relationship quality) in a nationally representative sample of adolescents followed into adulthood. Data were from 14,800 participants who completed in-home interviews during Wave I (grades 7–12) and Wave IV (24–32 years) of the National Longitudinal Study of Adolescent to Adult Health. Using latent class analysis, we identified three profiles of adolescent social support across parents, friends, teachers, and adults: (1) high support from all sources, (2) low teacher support and high support from other sources, and (3) low teacher/adult and moderate parent/friend support. The third profile reported significantly higher increases in depressive symptoms from adolescence to young adulthood and lower romantic relationship quality in young adulthood than the other two profiles, but the “low teacher/high other support” group did not significantly differ from the “high support from everyone” group. Furthermore, multiple regression analyses indicated that adult and teacher support each interacted with parent support to predict outcomes during adulthood. These results highlight the advantage of having multiple supports in one’s social network and emphasize the importance of understanding how adolescents’ overall profile of relationships promotes their well-being in young adulthood.
Compression versus no compression after endovenous radiofrequency ablation: A meta-analysis of randomized controlled trials
Authors: Zhang Dengxiao , Shi Chaohai , Zhang Yuan , Cui Qi , Zhai Shaobo , Huang Yalong , Zhou Cong , Chen Quan 
Published: June 2022

Objectives The aim of this meta-analysis was to compare compression with no-compression, after radiofrequency endothermal ablation of a truncal varicose vein. Methods Databases, such as PubMed, Embase, Cochran Library, and Web of Science, were independently searched by two researchers for relevant literature, preliminary screening was performed, and the full text was read to select studies that met the inclusion criteria. The quality of the included literature was evaluated using the Cochrane Risk of Bias tool, and meta-analysis was performed using Review Manager 5.4. Results A total of four randomized controlled trials were included and a total of 552 patients were involved. Among them, 273 patients were in the compression group and 279 in the no-compression group. Meta-analysis results showed that the pain using the 100 mm Visual Analogue Scale was lower in the compression group than the pain in the no-compression group (MD = −4.22, 95% CI = −7.95 − −0.49, p = 0.03). No significant differences in terms of occlusion rate (RR = 0.99, 95% CI = 0.96–1.02, p = 0.55), Aberdeen Varicose Vein Questionnaire (MD = 0.46, 95% CI = −0.80–1.73, p = 0.47), and complications (OR = 1.33, 95% CI = 0.61–2.94, p = 0.47) were observed between groups. Conclusions This meta-analysis suggests that compression therapy reduced post-operative pain compared to the no-compression group. However, no additional advantages were observed in terms of occlusion rates, quality of life scores and complications.
Preparation and thermal properties of modified binary paraffin - Hexadecylamine shaped composite phase-change energy storage materials
Authors: Hu Linna , Hao Wenxiu , Jiang Ruinian , Xu Xiao 
Published: June 2022

Binary paraffin has attracted much attention because it can control the phase change temperature range and has good flexibility. To improve the latent heat effect, a modified binary paraffin—hexadecylamine—ceramsite shaped composite phase-change energy storage material was prepared in this study through eutectic mixing and vacuum adsorption method. With eutectic binary paraffin—hexadecylamine as the core material, ceramsite as the carrier shell material and nano aluminum nitride (AlN) as the heat conduction enhancer. The thermal stability of the composites was characterized using a temperature recorder, differential scanning calorimetry (DSC), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and X-ray diffraction (XRD). The results showed that the optimal mass ratio of the eutectic phase-change material was solid paraffin: liquid paraffin: hexadecylamine = 50: 18: 32. The optimal mixture has a phase-change temperature of 26.5°C and a latent thermal value of 204.50 J/g, indicating that it has good heat storage performance. The phase-change temperature was 1.2°C earlier after the addition of 0.5% AlN, and the heat rate of storage was also improved. The mass ratio of the composite phase-change materials and ceramsite was 27.5: 72.5 is achieved by vacuum adsorption into the ceramsite. The phase-change materials are evenly dispersed and the ceramsite is well wrapped. It has good thermal stability, as verified by a 500 accelerated heating-cooling circulations below 60°C, and has great potential for the development of new building energy storage materials.
Cranial Morphology Associated With Syndromic Craniosynostosis: A Potential Detection of Abnormality in Patient's Cranial Growth Using Angular Statistics
Authors: Zulkipli Nur Syahirah , Satari Siti Zanariah , Hariri Firdaus , Abdullah Norli Anida , Wan Yusoff Wan Nur Syahidah , Hussin Abdul Ghapor 
Published: June 2022

Introduction Apert, Crouzon, and Pfeiffer syndromes are common genetic syndromes related to syndromic craniosynostosis (SC), whereby it is a congenital defect that occurs when the cranial growth is distorted. Identifying cranial angles associated with these 3 syndromes may assist the surgical team to focus on a specific cranial part during the intervention planning, thus optimizing surgical outcomes and reducing potential morbidity. Objective The aim of this study is to identify the cranial angles, which are associated with Apert, Crouzon, and Pfeiffer syndromes. Methods The cranial computed tomography scan images of 17 patients with SC and 22 control groups aged 0 to 12 years who were treated in the University Malaya Medical Centre were obtained, while 12 angular measurements were attained using the Mimics software. The angular data were then divided into 2 groups (patients aged 0 to 24 months and >24 months). This work proposes a 95% confidence interval (CI) for angular mean to detect the abnormality in patient's cranial growth for the SC syndromes. Results The 95% CI of angular mean for the control group was calculated and used as an indicator to confirm the abnormality in patient's cranial growth that is associated with the 3 syndromes. The results showed that there are different cranial angles associated with these 3 syndromes. Conclusions All cranial angles of the patients with these syndromes lie outside the 95% CI of angular mean of control group, indicating the reliability of the proposed CI in the identification of abnormality in the patient's cranial growth.
Duration of Heart Failure With Reduced Ejection Fraction Associated With Electrocardiographic Outcomes Before and After Sacubitril/Valsartan
Authors: Lin Po-Lin , Lee Ying-Hsiang , Liu Lawrence Yu-Min , Tsai Cheng-Ting , Yang Ten-Fang , Chiou Wei-Ru , Hsieh Mu-Yang , Chang Hung-Yu , Huang Chun-Che 
Published: June 2022

Aim: Changes in QRS duration in patients with heart failure with reduced ejection fraction (HFrEF) after sacubitril/valsartan therapy is not fully understood. This study aimed to assess the association of duration of HFrEF diagnosis with electrocardiographic and echocardiographic outcomes between before and after sacubitril/valsartan. Methods: We included HFrEF patients who received naïve sacubitril/valsartan therapy for ≥3 months, between January 2016 and March 2018. All patients were divided into 2 groups based on their duration of HFrEF. Generalized linear models were analyzed the cardiac outcomes after sacubitril/valsartan therapy by HFrEF duration. Results: Among these, 42 patients were HFrEF duration of <1 year and 47 patients were ≥1 year. The mean difference of QRS duration was lesser in the <1-year group than in the ≥1-year group (−2.3 msec vs 6.3 msec; P = .029). However, the mean difference of left ventricular ejection fraction (LVEF) was higher in the ≥1-year group (13.8% vs 5.8%; P = .008). After adjusting for patient demographics and clinical characteristics, the ≥1-year group had a significantly prolonged QRS duration (coefficient = 11; 95% confidence interval [CI], 0.3-21.7) and an unfavorable LVEF recovery (coefficient = −10.3; 95% CI −14.5 to −6.1) compared with the <1-year group. Conclusion: Prolonged QRS durations and unfavorable LVEF recoveries after sacubitril/valsartan therapy were observed in patients with HFrEF duration of ≥1 year. Earlier diagnosis of HFrEF and appropriate medication treatment may be beneficial in the improvement of QRS duration and LVEF recovery.
XEN® 63 gel stent to treat a refractory uveitic glaucoma: A case report
Authors: Serrar Yasmine , Rezkallah Amina , Kodjikian Laurent , Poli Muriel , Mathis Thibaud , Denis Philippe 
Published: June 2022

Purpose To describe the effectiveness of the XEN® 63 gel stent in a refractory uveitic glaucoma after failure of an Ahmed Glaucoma Valve. Case description We report the case of a 54-year-old man with a history of uveitic glaucoma on his left eye due to Fuchs heterochromic iridocyclitis and neovascular glaucoma after a central retinal vein occlusion. Pre-operative intraocular pressure was 30 mmHg despite a QD (once-daily) dosed bimatoprost 0.3 mg and timolol 5 mg topical medication. At week 1, the eye exam showed an intraocular pressure of 6 mmHg with a well-formed bleb, a very mild hyphema and a localized choroidal detachment. At month 1, intraocular pressure was 14 mmHg with a formed bleb. Both hyphema and choroidal detachments had resolved. After a year, intraocular pressure was 16 mmHg without any medication and the bleb was still well-formed. Conclusion The XEN® 63 gel stent provides a good intraocular pressure reduction and can be an efficient alternative for tube and filtration surgery in refractory glaucoma. Its long-term effectiveness needs to be evaluated.
Evenness of Dietary Protein Intake Is Positively Associated with Lean Mass and Strength in Healthy Women
Authors: Johnson Nathaniel R , Kotarsky Christopher J , Mahoney Sean J , Sawyer Bailee C , Stone Kara A , Byun Wonwoo , Hackney Kyle J , Mitchell Steven , Stastny Sherri N 
Published: June 2022

Background: Evenness of protein intake is associated with increased lean mass, but its relationship with muscle strength and performance is uncertain. Objectives: We determined the association of evenness of protein intake with lean mass, muscle strength and endurance, and functional ability. Design: This was a cross-sectional study. Setting: Data were collected at a research university in the upper midwestern United States. Participants: One hundred ninety-two healthy women, aged 18 to 79 years, mean ± SEM 41.9 ± 1.3, completed the study. Measurements: Dietary intake was assessed using 3-day food diaries verified with food frequency questionnaires. To assess evenness of protein intake, the day was divided into 3 periods: waking to 11:30, 11:31 to 16:30, and after 16:30. Lean mass was measured with dual energy X-ray absorptiometry. Lower-body muscle strength and endurance were determined using isokinetic dynamometry. Upper-body muscle strength was maximal handgrip strength. Functional ability was assessed using 6-m gait speed and 30-second chair stand tests. Accelerometry measured physical activity. Results: Intakes of 25 g or more of protein at 1 or more of the 3 periods was positively associated with lean mass (β ± S.E.; 1.067 ± 0.273 kg, P < .001) and upper-body (3.274 ± 0.737 kg, P < .001) and lower-body strength (22.858 ± 7.918 Nm, P = .004) when controlling for age, body mass index, physical activity, and energy and protein intakes. Consuming at least 0.24 g/kg/period for those under 60 years and 0.4 g/kg/period for those 60 years and older was related to lean mass (0.754 ± 0.244 kg, P = .002), upper-body strength (2.451 ± 0.658 kg, P < .001), and lower-body endurance (184.852 ± 77.185 J, P = .018), controlling for the same variables. Conclusions: Evenness of protein intake is related to lean mass, muscle strength, and muscular endurance in women. Spreading protein intake throughout the day maximizes the anabolic response to dietary protein, benefiting muscle mass and performance.
Pregnancy and delivery in patients with Charcot-Marie-Tooth disease and related disorders
Authors: Skorupinska Mariola , Ramdharry Gita , Byrne Bridgette , Laurá Matilde , Reilly Mary M 
Published: June 2022

Background Charcot–Marie–Tooth disease is the most common inherited peripheral neuropathy and many patients with Charcot–Marie–Tooth are women of childbearing age. Guidelines for managing pregnancy in Charcot–Marie–Tooth are lacking. Aims To assess the impact of pregnancy on Charcot–Marie–Tooth and how Charcot–Marie–Tooth affects pregnancy, delivery and postnatal care. Methods A retrospective questionnaire exploring disease course during pregnancy, delivery, pregnancy complications, anaesthetic management and puerperium was administered to 92 patients with Charcot–Marie–Tooth and related disorders. Results Worsening of Charcot–Marie–Tooth symptoms were reported in 37% of pregnant patients which resolved after delivery in half of the patients. No significant increase in pregnancy, delivery and anaesthetic complications were observed and the type of delivery did not significantly differ from the normal population. Conclusions While these results are reassuring, ideally an international prospective study should be done to confirm these results and to develop practice guidelines on the management of pregnancy in Charcot–Marie–Tooth.
Three Approaches to the Inquiry into Teacher Identity: A Narrative Review Enlightened by Habermas's Human Interests
Authors: Rensijing (刘任思静) Liu , Hongbiao (尹弘飚) Yin 
Published: June 2022

Purpose This paper attempts to review and conceptualize how different scholars approach research on teacher identity through the lens of three human interests defined by Jürgen Habermas. Design/Approach/Methods This literature review, guided by Habermas's three human interests, illustrates the characteristics of three different approaches to the inquiry into teacher identity. Findings This paper summarizes three approaches to researching teacher identity and their characteristics, namely the technical approach, the practical approach, and the critical approach. The implications for future research and teacher development are also discussed. Originality/Value By incorporating Habermas's three human interests into teacher identity inquiries, this article offers a theoretical narrative review of the approaches to investigating teacher identity. Strengths and weaknesses of each approach as well as the possibility of a combined application of different approaches provide an original discussion of teacher identity research.