bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associations of adipokines and metabolic hormones with low-density lipoprotein hypercholesterolemia in men and women under 45 years of age
Authors: Kashtanova Е. V. , Polonskaya Yа. V. , Shramko V. S. , Shcherbakova L. V. , Stakhneva Е. М. , Sadovski E. V. , Spiridonov A. N. , Ragino Yu. I. 
Published: December 2022

Aim To study the adipokine profile in young people with hypercholesterolemia and low-density lipoproteins (LDL) and to evaluate the relationship between concentrations of LDL cholesterol (LDL-C) and metabolic hormones in men and women younger than 45 years. Material and methods This study included 304 subjects (group 1, 56 men with LDL-C concentration <2.1 mmol/l; group 2, 87 men with LDL-C concentration ≥4.2 mmol/l; group 3, 90 women with LDL-C concentration <2.1 mmol/l; and group 4, 71 women with LDL-C concentration ≥4.2 mmol/l). Serum concentrations of total cholesterol (C), triglycerides (TG), high-density lipoprotein C, and glucose were measured by an enzymatic assay with ThermoFisher Scientific kits and a KonelabPrime 30i biochemical analyzer. LDL-C was calculated using the Friedewald’s formula. Concentrations of amylin, C-peptide, ghrelin, glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1 (GLP-1), glucagon, interleukin 6, insulin, leptin, monocyte chemotactic protein 1 (MCP-1), pancreatic polypeptide (PP), peptide YY (PYY), tumor necrosis factor alpha (TNF-α), adiponectin, adipsin, lipocalin-2, plasminogen activator inhibitor 1 (PAI-1), and resistin were measured by multiplex analysis (Human Metabolic Hormone V3 and Human Adipokine Panel 1 panels).Results The groups differed in traditional cardiometabolic risk factors. In the male and female patient groups with LDL-C ≥4.2 mmol/l, the prevalence of impaired fasting glucose, incidence of insulin resistance, TG, and TC were higher than in subjects with LDL-C <2.1 mmol/l. The odds for the presence of LDL hypercholesterolemia (LDL-C ≥4.2 mmol/l) were significantly associated with increased concentrations of C-peptide and lipocalin-2 in men and with increased concentrations of lipocalin-2 and decreased concentrations of GLP-1 in women (р<0.05).Conclusion Increased concentrations of LDL-C in young people were associated with changes in the adipokine profile and with the presence of metabolic syndrome components. These results were confirmed by changes in blood concentrations of metabolic markers that characterize disorders of metabolic processes.
The transition between early childhood education and primary education: a literature review
Authors: Kucybala Fabíola dos Santos , Felicetti Vera Lucia , Robayo Adriana del Rosario Pineda 
Published: December 2022

The transition between Early Childhood Education and Primary Education is a process that permeates the academic lives of children, so it is fundamental that it takes place in an interconnected way, with an integrated curriculum and the use of recreational situations and experiences that contribute towards literacy. This literature review analyzes the productions and foundations in the educational landscape and in the field of knowledge production regarding the transition between these two stages of Basic Education, by analyzing articles published in journals classified as Qualis A1 in Brazil, according to the assessment carried out by CAPES in 2019. The articles analyzed had themes aimed at the following a priori categories: Childhood Education; Teacher Knowledge and Practices; Curriculum and Teaching and Learning. After analyzing these articles, guided by Textual Discourse Analysis, three categories and five subcategories emerged. Among the results, we found that most of the articles addressed issues related to the curriculum, literacy and issues related to early childhood, reinforcing the importance of establishing an interconnected and systematic study between the two stages of Basic Education. However, research in the area of transition is insignificant, despite the evident importance of this topic.
A Community Health Worker–Based Intervention on Anthropometric Outcomes of Children Aged 3 to 21 Months in Urban Pakistan, 2019–2021
Authors: Shonchoy Abu S. , Akram Agha A. , Khan Mahrukh , Khalid Hina , Mazhar Sidra , Khan Akib , Kurosaki Takashi 
Published: December 2022

Objectives. To evaluate the impact of a community health worker–based “in-home growth monitoring with counseling” (IHGMC) intervention on anthropometric outcomes in Pakistan, where 38% of children younger than 5 years are stunted. Methods. We used an individual, single-blind, step-wedge randomized controlled trial and a pure control group recruited at endline. We based the analysis on an intention-to-treat estimation using the coarsened exact matching (CEM) method for sample selection among treatments and the control. We conducted the baseline in July 2019 and completed endline in September–October 2021. We recruited 1639 households (treated: 1188; control: 451) with children aged 3 to 21 months who were residing in an urban informal settlement area. The CEM sample used for analysis numbered 1046 (treated: 636; control: 410). The intervention continued for 6 months. Results. Compared with the control group, the height-for-age z-score in the IHGMC group increased by 0.58 SD (95% confidence interval [CI] = 0.33, 0.83; P = .001) and the weight-for-age z-score by 0.43 SD (95% CI = 0.20, 0.67; P < .01), measured at endline. Conclusions. IHGMC substantially improved child anthropometric outcomes in disadvantaged localities, and this impact persisted during the COVID-19 pandemic. Trial Registration. AER-RCT registry (AEARCTR-0003248). (Am J Public Health. 2023;113(1):105–114. https://doi.org/10.2105/AJPH.2022.307111 )
Trends in Degree Conferrals, Degree-Associated Debt, and Employment Outcomes Among Undergraduate Public Health Degree Graduates, 2001‒2020
Authors: Leider Jonathon P. , Burke Emily , Nguyen Ruby H. N. , Plepys Christine , Kirkland Chelsey , Resnick Beth , Magaña Laura 
Published: December 2022

Objectives. To characterize the trends in degree conferrals, degree-associated debt, and employment outcomes among undergraduate public health degree (UGPHD) graduates. Methods. We reported administrative data on degree conferrals from 2001 to 2020 from the National Center for Education Statistics (NCES). For alumni graduating from 2015 to 2019, we also reported degree-associated debt and earnings 1 year after graduation compiled by NCES. Finally, we utilized a data set on 1-year postgraduation employment outcomes for graduates from 2015 to 2020 from the Association of Schools and Programs of Public Health. Results. As of 2020, more than 18 000 UGPHDs were awarded each year, more than 140 000 in total over the past 20 years. UGPHD graduates are highly diverse, with more than 80% being women and 55% being individuals from communities of color. We find alumni worked mostly in for-profit organizations (34%), health care (28%), nonprofits (11%), academic organizations (10%), government (10%), and other (6%). Degree-associated debt was $24 000, and the median first-year earnings were $34 000. Conclusions. While growth in UGPHD conferrals has slowed, it remains among the fastest-growing degree in the nation. However, the limited pathways into government remains a significant challenge. (Am J Public Health. 2023;113(1):115–123. https://doi.org/10.2105/AJPH.2022.307113 )
The Sequential Multiple Assignment Randomized Trial for Controlling Infectious Diseases: A Review of Recent Developments
Authors: Wang Xinru , Chakraborty Bibhas 
Published: December 2022

Infectious diseases have posed severe threats to public health across the world. Effective prevention and control of infectious diseases in the long term requires adapting interventions based on epidemiological evidence. The sequential multiple assignment randomized trial (SMART) is a multistage randomized trial that can provide valid evidence of when and how to adapt interventions for controlling infectious diseases based on evolving epidemiological evidence. We review recent developments in SMARTs to bring wider attention to the potential benefits of employing SMARTs in constructing effective adaptive interventions for controlling infectious diseases and other threats to public health. We discuss 2 example SMARTs for infectious diseases and summarize recent developments in SMARTs from the varied aspects of design, analysis, cost, and ethics. Public health investigators are encouraged to familiarize themselves with the related materials we discuss and collaborate with experts in SMARTs to translate the methodological developments into preeminent public health research. (Am J Public Health. 2023;113(1):49–59. https://doi.org/10.2105/AJPH.2022.307135 )
Health Justice: A Framework for Mitigating the Impacts of HIV and COVID-19 on Disproportionately Affected Communities
Authors: Alang Sirry , Blackstock Oni 
Published: December 2022

Health crises have a disproportionate impact on communities that are marginalized by systems of oppression such as racism and capitalism. Benefits of advances such as in the prevention and treatment of HIV disease are unequally distributed. Intersecting factors including poverty, homophobia, homelessness, racism, and mass incarceration expose marginalized populations to greater risks while limiting access to resources that buffer these risks. Similar patterns have emerged with COVID-19. We identify comparable pitfalls in our responses to HIV and COVID-19. We introduce health justice as a framework for mitigating the long-term impact of the HIV epidemic and COVID-19 pandemic. The health justice framework considers the central role of power in the health and liberation of communities hit hardest by legacies of marginalization. We provide 5 recommendations grounded in health justice: (1) redistribute resources, (2) enforce mandates that redistribute power, (3) enact legislation that guarantees support for people with long-haul COVID-19, (4) center experiences of the most impacted communities in policy development, and (5) evaluate multidimensional effects of policies across systems. Successful implementation of these recommendations requires community organizing and collective action. (Am J Public Health. 2023;113(2): 194–201. https://doi.org/10.2105/AJPH.2022.307139 )
Analysis of Internal Control Information System Product Conversion Cycle Management
Authors: Maghfiro Putri Lailatul , Setiyono Wisnu Panggah 
Published: December 2022

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Application of coupled FICA-FCM feature extraction and QPSO-SVM classifier model to predict coal and gas outbursts
Authors: Liu Xuning , Zhang Zixian , Li Zhixiang , Zhang Guoying 
Published: December 2022

Abstract
The coal and gas outbursts samples data are affected by all kinds of influencing factors, the accuracy of classification on these sample data is not high, the classification of some samples always have errors, which may be inaccurate annotation. In order to reduce the impact of noise data caused by the labeling errors on classification, this paper proposes a combination of classifier and clustering analysis model, which is used to improve the prediction accuracy of coal and gas outbursts. First, the high-order statistical characteristics of fast independent component analysis(FICA) method are used to extract the features of coal and gas outbursts sample data to obtain the independent nonlinear main metadata; Then, the fuzzy clustering mean (FCM) algorithm is used to cluster the coal and gas outbursts samples. Finally, based on improved clustering analysis results, the support vector machine(SVM) classifier based on quantum particle swarm optimization(QPSO) algorithm is used to compare the classification results with the existing labeled results, and the classification results are corrected to improve the classification accuracy. The results show that the performance of coupling model is significantly better than other exiting classifiers for coal and gas outbursts prediction.
Single DVCC based High Frequency Flux Controlled Memristor Emulator and its Experimental Results
Authors: Sharma Pankaj Kumar , Ranjan Rajeev Kumar 
Published: December 2022

Abstract
In this article, a flux-controlled memristor emulator is proposed. The proposed memristor emulator is designed using a single DVCC, three MOSFETs, and one capacitor. Among three MOSFETs, two MOS is used to create an active resistor, and one MOS is used to generate the multiplication factor required for the memristor emulator. The proposed emulator work for both incremental and decremental configurations. PSpice simulation with 180 nm CMOS technology is performed to validate the proposed memristor emulator. The proposed design operates up to 100 MHz frequency. The proposed memristor emulator is experimentally verified using AD844AN and CD4007 ICs. A high pass filter is implemented using the emulator for validating the resistive property of the proposed memristor emulator.
Association of onset-to-surgery time with morbidity and mortality among patients with perforated peptic ulcer: an observational cohort study
Authors: Tan Kanglian , Tan Zhijian , Liang Hailong , Gai Juanjuan , Xie Runsheng , Xiao Yingchao , Cai Bingqin , Chen Zhiqiang 
Published: December 2022

Abstract
Background: Rapid surgery is recommended to improve outcomes after peptic ulcer perforation (PPU), but understanding of the optimal onset-to-surgery time for PPU is limited. The purpose of this study was to assess the optimal time of onset to surgery for PPU that improved patient outcomes.
Methods: Data of eligible patients with PPU at three hospitals from 2019 to 2021 were retrospectively reviewed. Patients were categorized as a onset-to-surgery time of ≤ 12 h (early surgery [ES]) or > 12 h (late surgery [LS]). The primary outcome was 30-day sepsis morbidity. Secondary outcomes included 30-day postoperative morbidity and 30-day mortality. Patients’ characteristics and surgical outcomes were also compared. A P value of < 0.05 is considered as statistically significant.
Results: Of 245 patients, 231 (94.3%; mean [SD] age, 62.6 [18.2] years; 153 [70.5%] male)were included in the final analysis. Among the remaining cases, 50.7% underwent ES and 49.3% underwent LS. LS was associated with increased sepsis morbidity within 30 days (ORadj 5.71, 95% CI 2.02-16.10, P = 0.001). In secondary analyses, LS was associated with an increased risk of postoperative morbidity (ORadj 1.93, 95% CI 1.06-3.53, P = 0.032). The 30-day mortality was 0.9% in the ES group and 4.7% in the LS group (ORadj 3.93, 95% CI 0.43-36.05, P = 0.227). In addition, the estimated blood loss during ES was significantly less than that during LS (P = 0.004). The operative time and hospital stay were shorter in the ES group (both P <  0.005). Moreover, patients in the LS group were more likely to need for ICU admission (39.3% vs 22.7%, P = 0.008).
Conclusions: This cohort study found evidence that more favorable outcomes were achieved when surgery was performed within 12 hours after the onset of severe abdominal pain among patients with PPU. These findings provide more clarity around the optimal time of onset to surgery for patients with PPU. However, more well powered researches are needed to confirm the findings.
Impacts of COVID-19 on family violence in Thailand: prevalence and factor-influencers
Authors: Napa Wilai , Neelapaichit Nareemarn , Kongsakon Ronnachai , Chotivitayataragorn Somporn , Udomsubpayakul Umaporn 
Published: December 2022

Abstract
Background: The COVID-19 pandemic situation invaded our society. As a result, rising unemployment, insufficient household income, stress, and women and child health in the family. The study aimed to explore family violence and find the factors influencing family violence during the COVID-19 pandemic in Thailand. The study aimed to explore family violence and find the factors influencing family violence during the COVID-19 pandemic in Thailand.
Methods: This study used a mixed-method approach quantitative questionnaire followed up by qualitative interviews. A cross-sectional design was used to survey family violence among 1,285 women aged 15 years and over who lived with them and were recruited by stratified sampling. The family violence developed questionnaire used had a Cronbach alpha of 0.67 and inter-raters Kappa coefficient of 1.00. In addition, a descriptive qualitative instrument was employed to analyze the data sets from four focus group interviews with 32 staff from agencies working with family violence. The focus group questions related to the impacts of the COVID-19 pandemic’s impacts on family violence were developed based on researchers’ consensus and researchers independently analyzed data using content analysis
Results: The majority of participants were 45 years old (48%), married (61.1%), living in single-family (52.5%) settings, had lost their job (64.4%), and had moderate to severe economic constraints (37.8%, 40.6%, respectively). The prevalence of family violence was 42.2%. The violent behavior was primarily physical. Family income, stress, and substance abuse were associated with family violence. Findings from the qualitative interviews correlated with this date.
Conclusions: The COVID-19 pandemic affected families in terms of family violence. Women faced family violence behaviors, including psychological and physical violence, as well as sexual abuse which was associated with family income, economic status, stress, and substance abuse. Future interventions should address the issues of financial support and stress reduction.
Analysis and comparison of SARS-CoV-2 variant antibodies and neutralizing activity for 6 months after a booster mRNA vaccine in a healthcare worker population
Authors: Khan Saahir , Hosseinian Sina , Assis Rafael , Khalil Ghali , Luu Madeleine , Jain Aarti , Horvath Peter , Nakajima Rie , Palma Anton , Hoang Anthony , Razzak Eisa , Garcia Nicholas , Alger Joshua , Kalantari Mina , Silzel Emily , Jasinskas Algis , Zaldivar Frank , Schubl Sebastian , Felgner Philip 
Published: December 2022

Abstract
In the context of recurrent surges of SARS-CoV-2 infections, a detailed characterization of antibody persistence over a 6-month period following vaccine booster dose is necessary to crafting effective public health policies on repeat vaccination. To characterize the SARS-CoV-2 antibody profile of a healthcare worker population over a 6-month period following mRNA vaccination and booster dose. 323 healthcare workers at an academic medical center in Orange County, California who had completed primary vaccination and booster dose against SARS-CoV-2 were recruited for the study. A total of 690 blood specimens over a 6-month period were collected via finger-stick blood and analyzed for the presence of antibodies against 9 SARS-CoV-2 antigens using a coronavirus antigen microarray. The primary outcome of this study was the average SARS-CoV-2 antibody level as measured using a novel coronavirus antigen microarray. Additional outcomes measured include levels of antibodies specific to SARS-CoV-2 variants including Delta, Omicron BA.1, and BA.2. We also measured SARS-CoV-2 neutralization capacity for a subset of the population to confirm correlation with antibody levels. Although antibodies against SARS-CoV-2 wane throughout the 6-month period following a booster dose, antibody levels remain higher than pre-boost levels. However, a booster dose of vaccine generates approximately 3-fold lower antibody reactivity against Omicron variants BA.1 and BA.2 as compared to the original Wuhan strain. Despite waning antibody levels, neutralization activity against the original Wuhan strain is maintained throughout the 6-month period. In the context of recurrent surges of SARS-CoV-2 infections despite vaccination with booster doses, our data indicate that breakthrough infections are likely driven by novel variants with different antibody specificity and not by time since last dose of vaccination, indicating that development of vaccinations specific to these novel variants is necessary to prevent future surges of SARS-CoV-2 infections.
Application of analytical hierarchy process (AHP) for flood susceptibility mapping using GIS techniques in Thamirabarani river basin, Srivaikundam region, Southern India
Authors: S RICHARD ABISHEK. , A Antony Ravindran 
Published: December 2022

Abstract
The assessment of flood risk areas and the development of flood prevention methods depend on having flood susceptibility mapping. The flood-prone area of the Thamirabarani river basin in Srivaikundam region of Tamil Nadu was investigated. Evaluating flood risk using a composite risk and vulnerability index is a widely established tool that serves a critical element in the creation of flood risk reduction programmes. The current work is an attempt to analyze risk due to floods utilizing Analytical Hierarchy Procedures (AHP) including flood hazard factors and vulnerability indicators in a geographical information system environment. To define flood susceptibility maps at different spatial scales, Geographic Information Systems (GIS) are currently reliable and useful tool. This article compares the accuracy of various GIS-based flood risk assessment techniques. The geographical database was used to generate eight base layers: land use, drainage density, topographic wetness index (TWI), distance from rivers, river length, slope, DEM, and rainfall. Flood-vulnerable regions have been classified as very low, low, moderate, high, and very high. Each class was assigned a score in order to determine the risk zone. Using a GIS platform, the flood susceptibility was prepared by incorporating all of the thematic layers and the resulting flood frequency map. Local government administrators, researchers, and planners will find the flood susceptibility analysis with this model to be a very helpful and effective tool for developing flood mitigation plans.