bluuebunny/crossref_metadata_2025_split huggingface dataset:
Suture Education with Soft-Embalmed Cadavers: A Cut Above the Rest
Authors: Braasch Maxwell , Minchew Heather , Riffel Justin , Berbel German 
Published: March 2022

Introduction. Assess the efficacy of a surgical skills curriculum for third-year medical students focused on suturing training on soft embalmed cadavers, which simulate natural tissue more effectively for surgical procedures than traditionally preserved cadavers or surgical practice pads.
Methods. We performed a retrospective cohort study comparing pre- and post-survey results at a premier, accredited, nationally ranked academic medical center. Study participants were third-year medical students completing their required surgical clerkship rotation who participated in suturing sessions on both synthetic suture practice pads and soft-embalmed cadavers prior to beginning their operating room experience.
Results. A total of 40 participants were included with slightly more male participants. The majority of participants (52%) were interested in pursuing a non-surgical career. After participating in Clinical Anatomy Mentorship Program (CAMP), participants felt significantly more confident in their ability to suture in the operating room (median 4 [3-4] vs. 2 [1-3], p<0.001); in their knowledge of basic suturing supplies and instruments (median 4 [4-4] vs. 3 [2-3], p<0.001); and in their ability to determine when different suture techniques are appropriate in the operating room (median 3 [3-4] vs. 1 [1-2], p<0.001). Participants felt more confident in their ability to suture in the operating room after their experience suturing on soft-embalmed cadavers compared to suture practice pads (median 5 [4-5] vs. 4 [4-4], p=0.002).
Conclusions. Medical students' confidence in suturing skills and in the knowledge of important characteristics of suturing practice was significantly improved after a suture training session on soft-embalmed cadavers.
The economic burden of excessive sugar consumption in Canada: should the scope of preventive action be broadened?
Authors: Liu Siyuan , Munasinghe Lalani L. , Maximova Katerina , Taylor Jennifer P. , Ohinmaa Arto , Veugelers Paul J. 
Published: March 2022

Abstract
Objective
Excessive sugar consumption is an established risk factor for various chronic diseases (CDs). No earlier study has quantified its economic burden in terms of health care costs for treatment and management of CDs, and costs associated with lost productivity and premature mortality. This information, however, is essential to public health decision-makers when planning and prioritizing interventions. The present study aimed to estimate the economic burden of excessive free sugar consumption in Canada.

Methods
Free sugars refer to all monosaccharides and disaccharides added to foods plus sugars naturally present in honey, syrups, and fruit juice. Based on free sugar consumption reported in the 2015 Canadian Community Health Survey–Nutrition and established risk estimates for 16 main CDs, we calculated the avoidable direct health care costs and indirect costs.

Results
If Canadians were to comply with the free sugar recommendation (consumption below 10% of total energy intake (TEI)), an estimated $2.5 billion (95% CI: 1.5, 3.6) in direct health care and indirect costs could have been avoided in 2019. For the stricter recommendation (consumption below 5% of TEI), this was $5.0 billion (95% CI: 3.1, 6.9).

Conclusion
Excessive free sugar in our diet has an enormous economic burden that is larger than that of any food group and 3 to 6 times that of sugar-sweetened beverages (SSBs). Public health interventions to reduce sugar consumption should therefore consider going beyond taxation of SSBs to target a broader set of products, in order to more effectively reduce the public health and economic burden of CDs.
Features of the lesion of the vascular bed in purulent meningitis in children
Authors: Skripchenko Natalya V. , Egorova Ekaterina S. , Vilnits Alla A. , Gorelik Evgeniy Yu. 
Published: March 2022

Background. Purulent meningitis occupies one of the important places in the structure of neuroinfectious diseases in children and is the top ten places among the causes of death. The relevance of their study is due to the severity of the course, high rates of disability and deaths (839%). Damage to the vascular bed during neuroinfections, including purulent meningitis, is a mandatory component due to the predominantly hematogenous pathway of pathogens. The penetration of microorganisms through the blood-brain barrier into the cranial cavity and their hematogenous intrathecal circulation cause damage to the cerebral veins and arteries, leading to the development of vasculopathies and vasculitis.
Aim: To determine the features of vascular disorders in purulent meningitis in children.
Materials and methods. 100 children with purulent meningitis were examined, aged from 1 to 17 years 11 months, for the period since 2007 to 2020. All patients underwent neurological monitoring, etiological verification of diagnoses, determination of markers of endothelial dysfunction in the blood (D-dimer and desquamated endothelial cells), as well as MRI of the brain and MRI angiography.
Results. A complex lesion of the vascular system in purulent meningitis in children was proved, associated with both structural and functional properties of the vascular wall, as well as damage to the vasomotor function of the endothelium.
Conclusions. With purulent meningitis, there is damage to the vascular bed in the form of systemic vasculitis, including cerebral vessels, as evidenced by the presence of both markers of endothelial damage (desquamated endothelial cells and D-dimer) and changes in MRI and MRI angiography.
The use of tablet form of Polyoxidonium® for immunocorrection in children with secondary pyelonephritis
Authors: Kulygina Elena S. , Razin Maxim P. , Petrov Sergey B. , Dunaeva Elena B. , Makhneva Victoria A. 
Published: March 2022

Background. Some aspects of diagnostics and treatment of secondary pyelonephritis in children continue to be urgent tasks of pediatrics, especially with regard to immunological changes in this disease and the search for ways to optimally correct them. The purpose of the study: to study immunological disorders in children with VP and to determine the features of the use of the tablet preparation Polyoxidonium for their correction.
Materials and methods. The study is an open controlled prospective comparative single-center study, including two groups: observation and control. The observation group consisted of 40 children aged 515 years (Me = 10; Q1 = 6; Q3 = 14) with secondary pyelonephritis, realized against the background of congenital urological pathology. The control group consisted of 100 practically healthy children (health groups 1 and 2) aged 5 to 17 years (Me = 10; Q1 = 7; Q3 = 14). The patients underwent a standard examination, including in-depth immunological examination. The revealed violations of immunological resistance justified the inclusion of the domestic drug Polyoxidonium in the complex therapy of patients.
Results. 3 months after the treatment with the Polyoxidonium immunomodulator, an increase in the level of immunoglobulin A, the total number of lymphocytes, B cells, normalization of the number of CD19 lymphocytes, a decrease in the number of T lymphocytes and CD4 cells, an increase in phagocytosis and natural killers was noted.
Conclusion. Thus, complex therapeutic tactics for children with secondary pyelonephritis should be determined taking into account individual immunological shifts, namely: a reduced number of CD19 lymphocytes and the level of immunoglobulin A, an excessively high content of helper cells, to increase phagocytosis and the number of NK lymphocytes.
DeepShake: Shaking Intensity Prediction Using Deep Spatiotemporal RNNs for Earthquake Early Warning
Authors: Datta Avoy , Wu Daniel J. , Zhu Weiqiang , Cai Michael , Ellsworth William L. 
Published: March 2022

Abstract
We propose a deep spatiotemporal recurrent neural network, DeepShake, to project future shaking intensity directly from current ground-motion observations. DeepShake is a network-based forecasting model, able to predict future shaking intensity at all stations within a network given previously measured ground shaking. The model is not given any a priori knowledge of station locations; instead, it learns wave propagation amplitudes and delays solely from training data. We developed DeepShake with the 35,679 earthquakes from the 2019 Ridgecrest sequence. Tasked with alerting for modified Mercalli intensity (MMI) IV+ shaking on 3568 validation earthquakes at least 5 s in advance, DeepShake achieves an equal error rate of 11.4%. For the Mw 7.1 earthquake that hit Ridgecrest on 5 July 2019, DeepShake was able to provide targeted alerts to all stations inside the network 5 s prior to the arrival of MMI IV+ waveforms. DeepShake demonstrates that deep spatiotemporal neural networks can effectively provide one-step earthquake early warning with reasonable accuracy and latency.
Prediction of acute appendicitis using ultrasonography and modified Alvarado score — A prospective comparative study
Authors: Sonkariya Seema , Atal Devendra , Barolia Dinesh Kumar , Gambhir Sahil 
Published: March 2022

Acute appendicitis is not uncommon pathology but clinical diagnosis depends on skills of treating health officer. Now advancement in technology and easy availability of USG and CT scan centers make the easy diagnosis. Some time atypical presentation of acute appendicitis makes delay in diagnosis clinically. But, the modified Alvarado score make easy diagnosis of acute appendicitis and compatible to USG. This is a prospective comparative study conducted at RNT Medical College, Udaipur. This study was done in 50 patients, who were presented with pain right lower abdomen. to compare the sensitivity and specificity of modified Alvarado score and USG in diagnosis of acute appendicitis. there were 28 male and 22 female in this study. Age of Youngest patient in the study was 17 years and elder most was 57 years old. Anorexia was common symptoms after pain at right iliac fossa. Appendicectomy was done in 48 cases (96%) and taw cases were managed conservative. There were 34 (68%) patients who had modified Alvarado score more than 7. Modified Alvarado Score is a simple, practical and quick tool in securing diagnosis of acute appendicitis when score is &#62;7. Its results are similar to USG finding. It also helps to reduce the rate of negative appendicectomy. This study recommend appendicectomy in patients presenting with right iliac fossa pain in whom modified Alvarado score is 7 or more.
Successful Management of Rhino-Orbital-Cerebral Mucormycosis in a Child with Acute-on-Chronic Kidney Disease and Malnutrition
Authors: Al Reesi Mohammed , Al Muqbali Taleb , Al Ajmi Ahmed , Menon Varna 
Published: March 2022

Mucormycosis is a very rare fungal infection in children. It is caused by opportunistic fungi, and mainly affects immunocompromised patients. Early diagnosis is very important for a good outcome. Successful management requires the reversal of the underlying predisposing risk factors, surgical debridement and prompt administration of active antifungal agents, with liposomal amphotericin B being the first line therapy. This case, to the best of the authors’ knowledge, is the first rhino-orbital-cerebral mucormycosis to be reported on among Omani children. We highlight the importance of early diagnosis and prompt surgical and medical interventions in achieving a satisfactory outcome and we review the published literature in regard to the management.
Keywords: Mucormycosis; Sinusitis; Proptosis; Liposomal amphotericin B; Rhizopus; Posaconazole; Malnutrition.
Comparison of Price regarding the Domesticly Produced Medicine with the Price of the Similar Generic Medicine in India
Authors: Motevalli Mohammad Hosein , Dowlati Beirami Amirreza , Salimi Alireza , Yousefi Nazila 
Published: March 2022

Background: Supporting domestic production, by assuming its effect on the increase of accessibility, has been acknowledged as one of the main pharmaceutical policies from two dimensions of better provision of the drugs in the market and the increase of affordability by reducing prices. Therefore, it is expected from the domestic industries to produce pharmaceutical products that, in addition to increasing access and a sustainable supply of drugs, have competitive prices compared to the rival imported products, and reduce the medical costs imposed on patients and the health system. In this study the price of domestically produced drugs were compared with the price of the similar generic ones in India.
Methods: In this study, first, India was selected for comparison due to reasons such as low price, good quality, and the possibility of commerce despite sanctions. Then, from the Iranian pharmaceutical statistics, drugs which were only produced in Iran and were highly consumed with respect to the number of sales were included in the study. Prices of Iranian and Indian medicines were extracted from related valid websites. Finally, the price of 110 drugs were compared to determine the success rate of the domestic production industry in offering a reasonable price in the absence of foreign competitors.
Results: According to the findings from 57 % of the drugs under study, the median consumer price of these drugs in India was lower than the Iranian consumer price. If this comparison was made with the minimum price of the Indian medicine, this percentage would reach 88.
Conclusion: According to the findings mentioned above, it can be concluded that reducing the drugs prices and costs does not occur in all cases of domestic production, and this alone cannot be a good justification for a complete support of the domestic production of drugs; however, it should be noted that reducing costs is not the only reason to support domestic production of these products, and policy makers may act with regard to other factors in line with supportive policies; thus, the reasons regarding each case should be clearly defined for the health system.
Awareness of venous thromboembolism during long-haul flights among medical students – what do they really know about its prevention and treatment?
Authors: Wołkowski Maciej , Witkowska Jagoda , Zembura Marcela , Wojciechowska Eliza , Urbanek Tomasz 
Published: March 2022

WstępOgólnoświatowy ruch samolotowy osiąga rocznie liczbę 2,3 miliarda pasażerów. Powikłaniem długich lotów samolotem jest żylna choroba zakrzepowo-zatorowa (<i>venous thromboembolism</i> – VTE). Obejmuje ona zakrzepicę żył głębokich (<i>deep vein thrombosis</i> – DVT) i zatorowość płucną (<i>pulmonary embolism</i> – PE). Pomimo stosunkowo dużej częstości występowania tej choroby dostęp do informacji na temat czynników ryzyka oraz prewencji VTE jest ograniczony, co może wynikać ze zbyt małej liczby ogólnodostępnych artykułów dotyczących problemu, jak również z niedostatecznej uwagi poświęcanej tej jednostce chorobowej przez wykładowców i lekarzy. W pracy podjęto próbę oceny świadomości i wiedzy studentów medycyny na temat powikłań zakrzepowych związanych z długotrwałymi lotami samolotem.Materiał i metodyBadanie przeprowadzono między 10 listopada 2017 r. a 28 lutego 2018 r. w grupie 100 studentów medycyny Śląskiego Uniwersytetu Medycznego w Katowicach. Do badania wykorzystano kwestionariusz ankiety, który zawierał 12 pytań dotyczących wiedzy na temat występowania i patogenezy VTE związanej z długotrwałymi lotami samolotem. Uczestnicy badania opierali swoje odpowiedzi na wiedzy zdobytej podczas nauki na uniwersytecie.WynikiPrawidłowo częstość występowania VTE związanej z lotami samolotem wskazało 43% ankietowanych. Żaden ze studentów nie wskazał poprawnie czynników ryzyka VTE. Spośród badanych 40% znało patogenezę VTE w wyniku długotrwałych lotów. Zadowalający jest fakt, że 100% ankietowanych wiedziało, że odpowiedni ubiór może redukować ryzyko VTE podczas lotów samolotem.WnioskiAnkieta wykazała niski poziom wiedzy, jak również świadomości studentów związanej z zagrożeniem VTE podczas lotów samolotem. Wyniki badania powinny zostać uwzględnione podczas planowania na studiach medycznych zajęć dotyczących problematyki VTE.
Discrepancy of clinical, laboratory and instrumental picture in patients with pulmonary embolism
Authors: Pronin A. G. , Rakhmatullina A. R. , Glukhov D. K. 
Published: March 2022

The discrepancy of echocardiographic signs of right ventricular overload with the clinical picture and the level of plasma troponin concentration may underestimate the severity of the condition and lead to an inadequate choice of therapy, since all these parameters are currently determining the tactics of treatment of patients.Objective: to assess the prevalence and clinical characteristics of patients with pulmonary embolism with inconsistency of clinical, laboratory and instrumental picture.Material and methods. The course of the disease of 456 patients with pulmonary embolism was analyzed. 21 patients had a fatal outcome, the rest recovered. All patients underwent general clinical and biochemical blood tests, determination of the level of D-dimer and troponin, electrocardiography, echocardiography, ultrasound of the veins of the lower extremities, CT angiopulmonography, analysis of the results obtained.Results. It was found that among patients with high- and moderate-risk pulmonary embolism, women more often than men have an increase in the plasma concentration of troponin levels by 2.4 times, as well as a 3-fold discrepancy in the clinical and laboratory-instrumental picture with the presence of signs of right ventricular overload according to echocardiography data, which appear in dynamics. The phenomenon of "delayed echocardiography signs of overload of the right heart" is recorded in 0.8% of all patients with pulmonary embolism. At the same time, in patients with a high risk of early pulmonary embolism – associated death, its occurrence is 2.1%, and in patients with a moderately high risk – 4.4%. When comparing the prevalence of clinical and instrumental symptoms of pulmonary embolism in these patients with the data of patients with high and moderate risks of early death from pulmonary embolism, no statistically significant differences were found, including in terms of echocardiography in dynamics. The delay of еchocardiography signs of overload of the right parts of the heart" by 12–36 hours from the clinical picture, including in patients with hemodynamically significant pulmonary embolism, can be detected only with a series of еchocardiography, which allows, if necessary, timely review scope of treatment. In patients with pulmonary embolism with a pronounced lesion of the pulmonary artery, due to the rapidly progressing course of the disease, it is possible that the еchocardiography criteria of the disease do not have time to develop. In this case, an assessment of the stroke volume may play an important role, hover this parameter is non-specific for this disease.
Daftar Isi JPI Vol. 5 No. 1
Authors: Kunto Imbar 
Published: March 2022

DAFTAR ISI Volume 5, Nomor 1, Maret 2022.

Nur Rahmi, W. (2022). Penerapan Model Pembelajaran Assure Berbasis Daring/E-Learning pada Mata Kuliah Bahasa Inggris di Sekolah Tinggi Teknologi Sinar Husni. Jurnal Pembelajaran Inovatif, 5(1), 01 - 07. https://doi.org/10.21009/JPI.051.01

Ramadhan, M. A., Anisah, A., & Darmawan, O. D. (2022). Pengembangan E-Modul Berbasis Bim Autodesk Infraworks Pada Mata Pelajaran Konstruksi Jalan Dan Jembatan Di SMKN 1 Cikarang Barat. Jurnal Pembelajaran Inovatif, 5(1), 08 - 23. https://doi.org/10.21009/JPI.051.02

Kirana, P., Chaeruman, U. A., & Nursetyo, K. I. (2022). Pengembangan "Supermath&quot; sebagai Multimedia Pembelajaran Berbasis Gamifikasi untuk Matematika Kelas 2. Jurnal Pembelajaran Inovatif, 5(1), 24 - 29. https://doi.org/10.21009/JPI.051.03

Wahyu, U. A., Widyaningrum, R., & Ariani, D. (2022). Pengembangan Job Aid Remote Working untuk Peserta Magang Desain Grafis di Campaign.com. Jurnal Pembelajaran Inovatif, 5(1), 30 - 40. https://doi.org/10.21009/JPI.051.04

Ariani, D., Prawiradilaga, D. s., & Fatharani, W. (2022). Inovasi Gamifikasi Pada Pembelajaran Matakuliah Pengembangan Media Sederhana . Jurnal Pembelajaran Inovatif, 5(1), 41 - 48. https://doi.org/10.21009/JPI.051.05

Ahmad Dhenny Bagaskara, A. D. B., & Anindia Putra, I. N. T. (2022). Penerapan Pembelajaran Secara Daring Aplikasi Google Classroom Di SMPTK Galang Kasih. Jurnal Pembelajaran Inovatif, 5(1), 49 - 55. https://doi.org/10.21009/JPI.051.06

Pratiwi, M. E., Imbar, K., & Prawiradilaga, D. S. (2022). Pemanfaatan Prinsip Personalisasi Belajar dalam Pembelajaran Daring pada Mata Kuliah Designing E- Learning. Jurnal Pembelajaran Inovatif, 5(1), 56 - 62. https://doi.org/10.21009/JPI.051.07

Dian Rosdiana Noor, Siregar, E., & Chaeruman, U. A. (2022). Pengembangan Mobile Learning dengan Metode Studi Kasus untuk Mata Pelajaran PPKn Kelas VI di SDN Telajung 01. Jurnal Pembelajaran Inovatif, 5(1), 63 - 70. https://doi.org/10.21009/JPI.051.08

Khalidah, H., Mulyadi, & Ariani, D. (2022). Media Pembelajaran Permainan Papan Untuk Pendidikan Seksualitas di Lembaga DIAR. Jurnal Pembelajaran Inovatif, 5(1), 71 - 79. https://doi.org/10.21009/JPI.051.09

Muhammad Rafik, Vini Putri Febrianti, Afifah Nurhasanah, & Siti Nurdianti Muhajir. (2022). Telaah Literatur: Pengaruh Model Pembelajaran Project Based Learning (PjBL) terhadap Kreativitas Siswa Guna Mendukung Pembelajaran Abad 21. Jurnal Pembelajaran Inovatif, 5(1), 80 - 85. https://doi.org/10.21009/JPI.051.10
ANALISA KOMPUTASI ALGORITMA DES DENGAN RC4 UNTUK KEAMANAN DATA
Authors: Busran  , Jeri Widodo Putra  
Published: March 2022

Keamanan dan kerahasiaan data merupakan salah satu aspek terpenting dalam bidang komunikasi khususnya komunikasi yang menggunakan media komputer. Salah satu bidang ilmu pengetahuan yang digunakan untuk mengamankan data adalah kriptografi, kecepatan proses kriptografi dalam implementasinya sering menjadi hal yang penting diperhatikan. Penelitian bertujuan untuk mengetahui kecepatan waktu yang diperlukan dalam melakukan proses enkripsi dan dekripsi data antara dua algoritma yaitu algoritma RC4 dengan algoritma DES. Dari penelitian yang dilakukan menggunakan data berformat pdf, jpg, mp3 dimana ukuran data dari yang terkecil yaitu 1000kb sampai ukuran data yang terbesar 20mb yang dimasing - masing dilakukan pengujian sebanyak lima kali pengujian dan dihasilkan dari data yang ukuran terkecil dari algoritma RC4 dihasilkan waktu selama 0,23288/s dan data yang terbesar menghasilkan waktu 0,2529/s dan mengunakan algoritma DES dihasilkan waktu terkecil 0,23508/s dan waktu terbesar 0,2545/s, dari pengujian tersebut dapat diambil kesimpulan bahwa algoritma RC4 lebih cepat dari pada algoritma DES dalam melakukan komputasi data.

Data security and confidentiality is one of the most important aspects in the field of communication, especially communication using computer media. One of the fields of science that is used to secure data is cryptography, the speed of the cryptographic process in its implementation is often an important thing to pay attention to. This study aims to determine the speed of time required to encrypt and decrypt data between two algorithms, namely the RC4 algorithm and the DES algorithm. From research conducted using data in pdf, jpg, mp3 format where the data size from the smallest is 1000kb to the largest data size of 20mb which is each tested five times and the resulting data is the smallest size of the RC4 algorithm resulting in a time of 0 , 23288 / s and the largest data yield 0.2529 / s time and using the DES algorithm the smallest time is 0.23508 / s and the largest time is 0.2545 / s, from these tests it can be concluded that the RC4 algorithm is faster than the algorithm. DES in computing data.