bluuebunny/crossref_metadata_2025_split huggingface dataset:
Health Literacy and Health Outcomes in Chronic Obstructive Pulmonary Disease Patients: An Explorative Study
Authors: Azkan Ture Deniz , Bhattacharya Sudip , Demirci Hakan , Yildiz Tekin 
Published: March 2022

AimThis study aimed to evaluate the relationship between health literacy (HL) and chronic obstructive pulmonary disease (COPD) severity.MethodsPulmonary function test, sociodemographic features, Modified Medical Research Council (mMRC) dyspnea scale, COPD assessment test (CAT), and the European Health Literacy Survey Questionnaire were used. The study examined 13,760 patients who underwent a pulmonary function test. Out of 13,760 patients, 673 patients had FEV1/FVC values less than 70%. Those with FEV1/FVC&lt; 0.70 (n = 336) after the reversibility test were included in the study.ResultsThere was a significant decrease in HL and an increase in COPD severity (p &lt; 0.001). In multivariate analysis, the risk of severe COPD was 2.74 times higher in patients in the poor income level than in patients in the good income level. In patients with inadequate HL, the risk of developing severe COPD was 1.80 times higher. A significant difference was found in HL index scores among the groups in terms of education level and income level (p &lt; 0.001; p &lt; 0.001, respectively). The most difficult topics for patients with COPD were periodic health examinations, good practices in mental health, and adult vaccinations.ConclusionsPatients with COPD were found to be at a HL level well below the expected level. The risk of severe COPD increased with poor income and inadequate HL. Healthcare providers should be careful in accessing, understanding, and interpreting the health information of patients with inadequate HL. Therefore, patient education should be prioritized in the follow-up and in the treatment of patients with COPD. Physicians should pay maximum attention to patients with COPD in the regular use of drugs, their proper use, in taking preventive measures, and in adult vaccination.
Local Fixation of Colistin With Fibrin Spray: An in vivo Animal Study for the Therapy of Skin and Soft Tissue Infections
Authors: Janko Maren , Dust Fabian , Wagner Pia Viktoria , Gurke Robert , Frank Johannes , Henrich Dirk , Marzi Ingo , Verboket René Danilo 
Published: March 2022

ObjectiveSkin and soft tissue infections (SSTI) are a commonly known entity of diseases associated with difficult treatment procedures. The current gold standard when there is a rapidly progressing infection of soft tissues with a risk of sepsis is radical surgical debridement accompanied by systemic antibiotic therapy. In clinical settings, local antibiotics alone or formulated within carrier material are commonly used alongside this therapy regimen. One possibility of local antibiotic application is the fixation of colistin with fibrin glue spray. It is not yet sufficiently researched how the local antibiotic concentrations remain as high as possible over time.MethodsWe conducted an animal study including 29 male Wistar rats inducing sterile back sores reaching the muscle fascia. We sprayed only colistin, simultaneously or consecutively, with fibrin glue in different groups in order to measure the tissue concentration of the antibiotic applied locally.ResultsAfter liquid chromatography and quadrupole mass spectrometry analysis, it could be demonstrated that in comparison to the colistin group, tissue concentrations of colistin stayed significantly higher in the wound tissue when it was fixed with fibrin glue. This was observed in both groups, the simultaneous as well as in the consecutively fibrin glue sprayed groups after colistin application.ConclusionThe fixation of colistin with the fibrin-glue-spray technique as a carrier for local antibiotic therapy is an easy and inexpensive method and shows promising potential for the treatment of SSTI.
Wedge Resection vs. Stereotactic Body Radiation Therapy for Clinical Stage I Non-small Cell Lung Cancer: A Systematic Review and Meta-Analysis
Authors: Peng Lei , Deng Han-Yu , Liu Zhen-Kun , Shang Qian-Wen , Huang Kai-Li , Zheng Qiang-Qiang , Li Wen , Wang Yun 
Published: March 2022

BackgroundWhether wedge resection or stereotactic body radiation therapy (SBRT) has better effectiveness in treatment of clinical stage I non-small cell lung cancer (NSCLC) patients remains unclear. Here we conducted the first meta-analysis to directly compare the survival outcomes of clinical stage I NSCLCs treated with wedge resection and SBRT.MethodsWe systematically searched studies from PubMed, Embase, and Corchrane Library up to October 1, 2021. Data for analysis mainly included overall survival (OS) and disease-free survival (DFS), which were obtained directly from the text results or calculated from the Kaplan–Meier survival curve. We used the standard random-effect model test (DerSimonian and Laird method) to analyze the pooled hazard ratios (HRs) and 95% confidence intervals (CIs). The Q-test and I2-test were used to assess heterogeneity. The stability of pooled HRs was examined by sensitivity analysis.ResultsSix retrospective studies with a total of 11,813 clinical stage I NSCLCs who received wedge resection or SBRT were included. The results showed that patients receiving wedge resection had a significantly better OS (HR = 1.20, 95% CI = [1.07, 1.34], P = 0.002) than those with SBRT, but no significant difference of DFS (HR 1.53, 95% CI = [0.83–2.83], P = 0.17) was observed. There was no significant heterogeneity during our analysis, but there may be potential publication bias among these studies.ConclusionsOur meta-analysis showed that clinical stage I NSCLCs treated with wedge resection had superior OS than those treated with SBRT. However, more prospective clinical trials should be well-designed to evaluate the optimal treatment modality of early-stage NSCLCs.
Circular RNAs as Diagnostic and Prognostic Indicators of Colorectal Cancer: A Pooled Analysis of Individual Studies
Authors: Long Cong , Xu Qiu-bo , Ding Li , Huang Li-juan , Ji Yong 
Published: March 2022

Background: Circular RNAs (circRNAs) have proven as a special subset of endogenous RNAs that are implicated in the tumorigenesis of various cancers. This study sought to evaluate the role of circRNAs in the diagnosis and prognosis of colorectal cancer (CRC).Methods: The online databases were searched for collecting relevant studies on circRNAs as diagnostic and prognostic biomarkers of CRC. Two researchers independently screened literature, extracted data, and evaluated the bias and risks of included studies. The diagnostic and prognostic indicators were merged and analyzed using STATA 12.0 software, and sources of heterogeneity were traced by the sensitivity analysis and the meta-regression test.Results: A total of 29 articles representing 2639 CRC patients were included. The pooled sensitivity, specificity, and area under the curve (AUC) of circRNAs in differentiating CRC from non-tumor control were 0.75 (95% CI: 0.69–0.80) and 0.74 (95% CI: 0.69–0.78) and 0.81, respectively. The survival analysis showed that up-regulations of up-regulated circRNAs were significantly related to dismal survival in CRC patients (HR = 2.38, p &lt; 0.001). A stratified analysis showed that the comprehensive diagnostic value of up-regualted circRNAs in CRC was higher than that of down-regualted circRNAs (AUC: 0.83 vs. 0.77; Z test, p &lt; 0.05). The efficacy of tissue-derived circRNAs in the diagnosis of CRC was equal to that of plasma/serum-derived ones (AUC: 0.81 vs. 0.82; Z test, p &gt; 0.05).Conclusion: Abnormally expressed circRNAs as auxiliary biomarkers present underlying value in the diagnosis and prognosis prediction of CRC.
Lung Ultrasound in Preterm Neonates as Useful Tool of Assessing the Condition of Lung Tissue and Pleural Cavity
Authors: Улезко Е.А. , Левандовский Е.В. 
Published: March 2022

За последние два десятилетия возросла частота рождения недоношенных детей. Вероятность летального исхода у новорожденных с массой тела менее 2500 г в 40 раз превышает таковую у детей с нормальной массой тела. Использование новых технологий в реанимации и интенсивной терапии новорожденных значительно улучшило выживаемость детей с экстремально низкой массой тела. Одной из основных причин перинатальной смертности является нарушение со стороны респираторной системы. Диагностика патологии органов дыхания, в частности легких, у недоношенных новорожденных в основном основывается на данных рентгенологического метода исследования. С целью минимизации воздействия вредных факторов, в частности ионизирующего рентгеновского излучения, в литературе предложен метод ультразвукового исследования легких. В статье представлен обзор литературы по методике ультразвукового исследования легких и описание основных патологических состояний.
The frequency of premature births has increased over the past two decades. The probability of fatal outcome in newborns with body weight less than 2500 g is 40 times higher than in children with normal weight. The use of new technologies in intensive care units has significantly improved the survival rate of infants with extremely low birth weight. One of the main causes of perinatal mortality is respiratory system disorders. Diagnosis of respiratory pathology, particularly in lungs, in premature newborns is mainly based on X-ray data. In order to minimize the impact of harmful factors, particularly ionizing X-rays, the method of ultrasound examination of the lungs has been proposed in the literature. The article presents a review of the literature on the method of lung ultrasound with a description of the main pathological conditions.
Psychological Image of a Medical Professional as a Component of Social Level of Image in Healthcare
Authors: Воронко Е.В. , Кузмицкая Ю.Л. , Бойко С.Л. , Сурмач М.Ю. 
Published: March 2022

В статье приводятся результаты изучения психологического образа медицинского работника. Психологический образ понимается авторами как компонент социального уровня имиджа в здравоохранении. Психологический образ медицинского работника содержит определенный набор профессионально значимых качеств, включающий коммуникативные, эмоционально-волевые, интеллектуальные личностные. Метод исследования: семантический дифференциал Ч. Осгуда. Эмпирическая база исследования – 126 врачей и пациентов. Представлен количественный и качественный анализ профилей психологического образа медицинских работников при разных объектах оценивания (врач и медицинская сестра). Проведенное исследование показало сформировавшиеся психологические образы врача как человека с хорошо развитыми коммуникативными и интеллектуальными личностными качествами, медицинскую сестру как человека с преобладающими коммуникативными, эмоциональными и волевыми качествами.
The article presents the results of studying the psychological image of a medical worker. The psychological image is understood by the authors as a component of the social level of image in the health care system. The psychological image of a medical worker contains a certain set of professionally significant qualities, including communicative, emotional – volitional, intellectual personal qualities. Research method: Ch. Osgood’s semantic differential. The empirical base of the study was 126 doctors and patients. A quantitative and qualitative analysis of the profiles of the psychological image of medical workers in different objects of assessment (doctor and nurse) was presented. The study showed the formed psychological images of a doctor as a person with well– developed communicative and intellectual personal qualities, a nurse as a person with prevailing communicative, emotional and volitional qualities.
Analysis of Non-fermenting Gram-Negative Bacteria Spreading and Their Resistance to Antimicrobial Agents
Authors: Зайцева В.Н. , Рогачева Т.А. , Анисько Л.А. , Соловей Н.В. 
Published: March 2022

В работе представлены результаты микробиологического исследования 430 клинических изолятов неферментирующих грамотрицательных бактерий (НГОБ), выделенных из биоматериала пациентов, госпитализированных в УЗ «Городская клиническая инфекционная больница» г. Минска в 2014–2019 гг. Проанализированы частота, динамика выделения и резистентность к антибактериальным лекарственным средствам. Установлено, что в спектре выделенных в указанный период микроорганизмов ведущими патогенами являлись ацинетобактер и синегнойная палочка. Среди нозологических форм доминировали инфекции дыхательных путей. Изучение чувствительности изолятов Acinetobacter различной видовой принадлежности к антибиотикам показало, что наибольшей эффективностью обладали глицилциклины (тигециклин) – 98,2% изолятов, полимиксины (колистин) – 96,2% изолятов. Близкими по активности были аминогликозиды и карбапенемы (56,5% и 55,6% изолятов соответственно). В отношении псевдомонад высокая антимикробная активность была у полимиксинов (колистин) – 93,5% изолятов, аминогликозидов (тобрамицин) – 71,8% изолятов и цефалоспоринов (цефепим) – 59,2% изолятов.
The article presents results of a microbiological study of 430 clinical non-fermenting gram-negative bacteria isolates. They were isolated from biomaterial of patients hospitalized in the Minsk Infectious Hospital for 2014–2019. It is found that in the spectrum of microorganisms isolated during the period, the leading pathogens were Acinetobacter and Pseudomonas. Acinetobacter’s sensitivity to antibiotics showed that most effective of glicylcycline (tihecycline) 98.2% of isolates fnd polymyxins (colistin) – 96.2%. Among Pseudomonas polymyxins (colistin) had high antimicrobialactivity of 93.5% of isolates, aminoglycoside (tobramicin) – 71.8% of isolates and cephalosporins (cephepime) – 59.2% of isolates.
Three-temperature modeling of laser-induced damage process in silicon
Authors: Venkat Prachi , Otobe Tomohito 
Published: March 2022

Abstract
Laser excitation in silicon from femto- to pico-second time scales is studied. We assume the three-temperature model which describes the dynamics of the distinct quasi-temperatures for electrons, holes, and lattice. Numerical results for damage threshold reproduce the experimental results not only quantitatively, but qualitatively as well, showing dependence on laser pulse duration. Comparison with experimental data suggests that electron emission and thermal melting are both responsible for damage in silicon. We found that electron–phonon relaxation time has a significant effect on pulse duration dependence of electron emission.
Perancangan Sistem Informasi Perpustakaan SMA N 1 Tengaran Menggunakan ROOT CAUSE ANALYSIS (RCA)
Authors: Mustofa Arifuddin , Rudianto Christ , Tanaem Penidas Fiodinggo 
Published: March 2022

Belum maksimalnya sekolah dalam pemanfaatan teknologi informasi membuat sekolah sedikit tertinggal dan kurang efektif dalam pelayanan peminjaman maupun pendataan buku, karena dalam pelayanan masih menggunakan sistem manual yaitu dengan menulis di buku peminjaman, sehingga dibutuhkan sistem informasi yang dapat membantu dalam pelayanan perpustakaan. Dalam perancangan sistem informasi perpustakaan digunakan metode analisis studi literatur, observasi, wawancara dan RCA (Root Cause Analysis) langsung kepada siswa dan petugas perpustakaan. RCA sendiri dipakai untuk pendekatan sebagai bahan analisis sebuah perancangan sistem untuk memahami sebuah peristiwa secara detail. Dokumentasi Perancangan sistem informasi ini menggunakan pemodelan Unified Modeling Language (UML) yaitu use case diagram, class diagram, activity diagram dan sequence diagram, hasil analisis dan perancangan ini diharapkan dapat membantu dalam pelayanan perpustakaan sehingga dalam proses peminjaman dan pendataan buku dapat dilakukan dengan lebih efektif
Pengembangan Pengembangan Sistem Peminjaman Barang Berbasis Online Pada Sistem Pengelolaan Aset FTI UKSW
Authors: Lelatobur BIllstein Maelgweyn Lelatobur Maelgwyn 
Published: March 2022

Proses peminjaman barang bagi civitas akademika umumnya dilakukan secara rutin. Namun, selama proses peminjaman barang terkadang petugas laboran mengalami kesulitan saat banyaknya peminjaman yang terjadi karena formulir harus diperiksa secara manual oleh petugas laboratorium. Oleh karena itu, peneliti akan merancang dan membangun sebuah sistem informasi peminjaman barang berbasis online yang dapat memudahkan petugas laboran dalam mengelola data barang.
Optimasi Penjadwalan Olahraga ITC 2021 Menggunakan Swap
Authors: Sulaiman Alda Muhammad , Muklason Ahmad 
Published: March 2022

Riset operasi memiliki salah satu bidang yakni penjadwalan olahraga. Topik ini menjadwalkan sebuah pertandingan olahraga dengan tidak melanggar batasan yang ada. Permasalahan penjadwalan olahraga saat ini menjadi semakin kompleks dengan banyaknya batasan yang ada. Kompetisi International Timetabling Competition on Sports Timetabling 2021 (ITC 2021) merupakan salah satu yang mengeluarkan dataset realworld terbaru. Optimasi kualitas penjadwalan olahraga untuk menurunkan nilai penalty pada solusi akhir dari penjadwalan merupakan focus dari penelitian ini. Penerapan algoritma ini mampu menghasilkan optimasi dengan rata-rata 10 dari solusi awal. Algoritma ini juga menghasilkan solusi yang konsistern selama 10.000.000 kali percobaan setiap dataset.
Perencanaan Strategis Sistem Informasi Menggunakan Metode Wetherbe (Studi Kasus : Kantor Sekretariat Majelis Rakyat Papua)
Authors: Fingkreuw Mardiana 
Published: March 2022

Majelis Rakyat Papua merupakan lembaga di provinsi Papua, Indonesia yang beranggotakan penduduk asli Papua yang berada setara dengan DPRD. Seiring berkembangnya Majelis Rakyat Papua, akan mempengaruhi kebutuhan teknologi informasi. Saat ini untuk menciptakan Papua yang damai sebagai perwujudan dari komitmen semua komponen masyarakat di provinsi ini, tugas dan fungsi Majelis Rakyat Papua maka dibutuhkan sistem informasi untuk mendukung aktivitas organisasi, layanan kepada stakeholder terutama kepada masyarakat asli Papua. Namun, sejauh ini pemanfaatan sistem informasi untuk mendukung tugas pokok dan fungsinya belum maksimal karena sebagian proses-proses itu masih dilakukan secara manual, sehingga kurang efektif dan efisien. Oleh karena itu akan dilakukan penelitian tentang Perencanaan Strategis Teknologi Informasi diperlukan untuk menjamin keberhasilan Majelis Rakyat Papua dalam memenuhi kebutuhan Teknologi informasi menggunakan metodologi Wetherbe. Melalui perencanaan teknologi informasi yang baik dan tepat, maka tujuan MRP baik itu bersifat jangka pendek mau jangka panjang dapat dilakukan secara optimal. Penyusunan rencana strategis sistem informasi telah menghasilkan portofolio aplikasi sistem informasi. Perencanaan strategis sistem informasi ini dapat menciptakan strategi yang selaras dengan strategi bisnis Sekretariat Majelis Rakyat Papua. Solusi kebutuhan sistem informasi berdasarkan hasil analisis yang sudah dilakukan, menghasilkan dua puluh dua sistem informasi.
Proposed Event Organizer Small Medium Business Enterprise Architecture in Pandemic Industry 4.0 Era
Authors: Karjadi Daniel Avian 
Published: March 2022

Covid-19 pandemic affects businesses around the world and the most impacted are small and medium event organizer business (SMB EO) that usually having social gathering event participated by a few hundred participants only. Digital transformation must be executed immediately to adapt to the conditions utilizing Industry 4.0 technology especially in recent pandemic era. This paper study the enterprise architecture design of SMB EO utilizing Industry 4.0 to survive in pandemic era and beyond. The enterprise architecture based on Togaf framework consists of business, application, information, and technology architecture is decribed in this paper. Small business doesn’t have the big capital on investing in technologies and during pandemic where certain technology is scarce may cause the business to be left behind. Choice of utilizing public social media and cloud providers according to the architecture is the key. Once the technology is adopted, business is digitalized then business can be ready to face future metaverse business model.
Al-Ghazali’s Metaphysical Philosophy of Spiritualism In The Book Of Ihya ‘Ulumuddin
Authors: Supriyanto Supriyanto 
Published: March 2022

This article tries to explore al-Ghazali’s views regarding philosophy—particularly metaphysical philosophy, and its influence on the establishment of al-Ghazali’s teachings as stated in the book ihya ʻulumuddin. The method used in this research is descriptive-qualitative method, and is included in the literature research (library research). The process of collecting data in this study is to make observations, in the sense of tracking various references that have relevance to the focus of the study, both from books, articles, and so on that function to support these data. The data analysis technique used in this research is the method of content analysis. In this analysis, the process of selecting, comparing, combining, and sorting information obtained from related data sources will be carried out to obtain valid inferences. From the studies conducted, it can be seen that: 1) Regarding the existence of God, al-Ghazali rejected the philosophical ideas of atheism (ad-dahriyun) and naturalism (al-thabi’iyun) as a whole. 2) al-Ghazali accepted the philosophical thought of divinity (ilahiyun), in several respects as a whole—for example logic, physics, mathematics, etc., and in terms of metaphysics, al-Ghazali accepted with certain conditions—in accordance with the texts of the Qur’an and hadith. 3) Al-Ghazali’s partial disagreement with metaphysical philosophers, such as Ibn Sina and al-Farabi is because both of them have collided with the principal “norms” in religion. 4) His refusal formed al-Ghazali’s thought structure which is presented in several of his works—including in the Book of ihya ʻulumuddin.
Hubungan Gaya Hidup dengan Kejadian Hipertensi pada Usia Dewasa di Kelurahan Subangjaya Wilayah Kerja Puskesmas Sukabumi Kota Sukabumi
Authors: Liawati Nunung , Sidik Tri Lusiani Maharani 
Published: March 2022

Hypertension is a disease that can cause complications towards other organs, and it will be more dangerous if the sufferer is classified as an adult. From 15 health centers in Sukabumi, Sukabumi Health Center occupies high number of hypertension cases at adult age about 706 or 16.3%. The purpose of this study is to determine the correlation between lifestyle and hypertension at adult age.
Hypertension is a condition when blood pressure systole is 140 mmHg or higher and diastolic blood pressure is 90 mmHg or higher. One of the factors that influence the incidence of hypertension is lifestyle.
This study used the type of correlational research with cross sectional approach. The population was 8,403 people with 383 people as the sample. Cluster Random Sampling was conducted to take the samples. The result of validity test of the lifestyle variable on 20 items was valid since the reliability was 0.787. The statistical analysis used Chi Square.
The results showed that healthy lifestyles was 52.5%, the incidence of non-hypertensive hypertension was 50.4%. There was correlation between lifestyle and the incidence of hypertension at adult age because it has p-value of 0.00.