bluuebunny/crossref_metadata_2025_split huggingface dataset:
Changes in Coagulation Status in Patients with β-Thalassemia in Iraq
Authors: Wadaha Hussein Abdalzehra , Meshay Hassan Dede , Khamees Mohammed Haseeb 
Published: July 2022

Background:
The pathogenesis β-thalassemia is characterized by anemia resulting from reduced β-globin synthesis with low hemoglobin A (HbA) production and higher production of hemoglobin A2 (HbA2) and fetal hemoglobin (HbF). However, thromboembolic events have been recently identified in patients with β-thalassemia due to hypercoagulable state.

Objectives:
The aim of this study was to evaluate the levels of some coagulation markers in Iraqi patients with β-thalassemia major and β-thalassemia intermedia.

Materials and Methods:
The study included three groups. The first group included patients with β-thalassemia major (n = 39), the second group included patients with β-thalassemia intermedia (n = 11), and third group included 20 apparently healthy control subjects. Each of prothrombin time (PT), activated partial thromboplastin time (APTT), antithrombin III (ATIII), and thrombin-antithrombin III (TAT) complex were measured according to the standard protocols.

Results:
Both PT and APTT in β-thalassemia major and β-thalassemia intermedia were higher than that of the control group with a highly significant difference (P = 0.002), whereas no significant differences were observed between patients with β-thalassemia major and β-thalassemia intermedia. Mean ATIII level was highest in the control group followed by β-thalassemia intermedia and then by β-thalassemia major groups (P < 0.001), whereas mean TAT complex was highest in thalassemia major group followed by β-thalassemia intermedia and then by control groups (P < 0.001).

Conclusions:
Prolonged PT and APTT in patients with β-thalassemia together with the reduction in the level of anticoagulant factor (ATII) suggest a role for liver impairment; however, the significantly higher TAT complex is suggestive of ongoing activation of coagulation cascade in patients with β-thalassemia.
Hypersensitivity Reactions to Liposomal Amphotericin in a Bone Marrow Transplant Patient
Authors: Alsajri Alaa Hussein , Al-Hishma Shadan Waleed , Shubber Mazin Abbas 
Published: July 2022

Introduction:
Hodgkin's lymphoma is one of the treatable types of blood cancer. Autologous bone marrow transplantation is used as one way to treat this disease. Neutropenic fevers are treated with antibiotics and antifungals, including amphotericin B. Adverse effects and hypersensitivity to liposomal amphotericin, Ambisome, are very uncommon compared with conventional amphotericin.

Case Report:
In this case, we noticed hypersensitivity reactions to the Ambisome, represented by an increase in body temperature, a drop in blood pressure, and hypo-oxygenemia, in addition to an increase in the heart rate.

Case Management:
The patient was treated with injections of hydrocortisone, chlorpheniramine, and normal saline, in addition to giving oxygen; he was improved.

Conclusion:
In spite of the few cases that have recorded hypersensitivity reactions to the Ambisome, it is necessary to conduct an allergy test and to monitor the patient well when giving the Ambisome, especially in the first dose.
Intracapsular Total Thyroidectomy Experience and Outcome for Benign Thyroid Diseases
Authors: Safi Mohammad Abbas , Alhelfy Sajid Hameed 
Published: July 2022

Background:
The total intracapsular thyroidectomy is a new procedure that removes all the thyroid tissue for benign thyroid diseases and two third of thyroid capsule with better intraoperative and post-operative consequences and less operative time than the capsular dissection and no recurrence rate of goiter or Graves’ disease that was detected during the follow up period.

Objectives:
To evaluate the outcome of total intracapsular thyroidectomy of benign thyroid diseases in term of safety and efficacy.

Patients and Methods:
This is a prospective descriptive study carried out in department of general surgery including a total of 80 patients with benign thyroid disease who underwent intracapsular total thyroidectomy. Patients were followed up for 6 months to 3 years with a median of 41.4 months for postoperative complications.

Results:
The mean age of the patients was 42.72 ± 8.12 years. The majority of patients were females (87.5%). The study showed that 97.5 % of the patient had no intraoperative complications. Postoperatively, only 4 patients (5%) developed complications. The mean operative time and blood loss was 71.78 ± 9.32 min and 82.8 ± 32.5 ml, respectively.

Conclusion:
The total intracapsular thyroidectomy is new procedure and more sophisticated than other operation types to treat benign thyroid disease. However, it is safe and efficient.
Prevalence and correlates of common mental disorders among children and adolescents in Blantyre-Urban, Malawi
Authors: Matandika Ian , Mategula Donnie , Kasenda Stephen , Adeniyi Yetunde , Muula Adamson 
Published: July 2022

BackgroundThe high global prevalence of mental disorders justifies the need to quantify their burden in the sub-Saharan Africa where there is a dearth of information. These mental disorders are linked to different socio-demographic factors.ObjectiveTo determine the prevalence of, and factors associated with mental disorders among children and adolescents in Blantyre City, Malawi.Methods
Children and adolescents aged 6 to 17 years were interviewed to determine their socio-demographic characteristics and assess their mental health status using the Strengths and Difficulties Questionnaire (SDQ) and Kiddie Schedule for Affective Disorders and Schizophrenia (K-SADS). Associations between mental disorders and socio-demographic characteristics were tested using Chi-square and logistic regression analysis.ResultsThe prevalence of symptoms of psychopathology on the SDQ was 7.3% (95%CI 4.8-10.5%) while for the K-SADS was 5.9% (95% CI 3.7%-8.9%). The prevalence of mental disorders across the age ranges of 6 to 12 years and 13 to 17 years was 5.4% and 7.9 % respectively. Males had a higher prevalence (7.1%) compared to females (4.7%). Conduct disorder was most prevalent (3.4%), followed by either type of ADHD- Attention Deficit Hyperactive Disorders (2.0%). Having a single parent (p<0.001), staying with a non-biological guardian (p<0.030), engaging in paid work (p<0.039), not attending school (p<0.019) and having teacher difficulties(p<0.028) were positively associated with a mental disorder.ConclusionThe socio-demographic factors associated with the risk of developing mental disorders may be important targets for mental health intervention programs.
An escape room activity to teach transitions-of-care: Student perceptions and lessons learned
Authors: Palasik Brittany N. , Cho Hae Jin , Atanda Adenike , Yuet Wei C. 
Published: July 2022

Introduction: Outside of experiential pharmacy education, there is a lack of curricular innovations focused on teaching transitions-of-care (TOC) to pharmacy students.
Description of Innovation: A TOC escape room activity was implemented for pharmacy students after learning about diabetes management in the didactic curriculum. A perceptions survey and pre-and post-activity knowledge assessment were administered to assess student knowledge attainment and allow for continual improvement of the activity.
Evaluation: The majority of students perceived that the escape room activity improved their readiness to treat patients with diabetes during care transitions. The escape room significantly improved knowledge, as demonstrated by an increase in mean scores between pre-and post-activity knowledge assessments.
Future Implementation: Though the escape room activity was perceived by pharmacy students as an enjoyable opportunity to apply material from a didactic setting, many challenges related to content development, assessment administration, logistics, and material complexity were experienced.
Evaluation of Pre-ingestive Citronella Residues using Ruminal In Vitro Techniques
Authors: Elihasridas Elihasridas , Zain Mardiati , Ningrat Rusmana Wijaya Setia , Erpomen Erpomen , Makmur Malik , Putri Ezi Masdia , Halimatuddini Halimatuddini 
Published: July 2022

Citronella residues (CR) have the potential to be used as an alternative to the fiber diet of ruminants. This study reports on the effects of pre-ingestive CR using ammonia (4 % dry matter (DM)) and fermentation (6 % DM) on in vitro rumen fermentation, metabolism, and methane (CH4) production. Four CR levels of 0, 25, 75, and 100 % DM were used. Each level was repeated 3 times and a complete randomized design method was used. The results showed that pre-ingestive CR significantly increased the pH rumen fluid but decreased ammonia-nitrogen concentration, total iso-volatile fatty acid (iso-VFA) production, and protozoa population (p < 0.01). The pre-ingestive CR significantly decreased the acetic acid composition and rumen microbial protein synthesis (p < 0.05), and significantly increased the proportion of propionic acid, n-butyric acid, and iso-valeric acid (p < 0.05). The total VFA production and rumen CH4 production did not significantly change (p > 0.05). In conclusion, pre-ingestive CR was compatible as a basal diet for ruminants.
HIGHLIGHTS

Pre-ingestive treated citronella residues used as substitute in ruminant fiber diet
100 % pre-ingestive citronella residues increased rumen fluid pH compared with napier grass
100 % pre-ingestive citronella residues reduced NH3, VFA, and protozoa
100 % pre-ingestive citronella residues had no effect on methane production
Rumen fermentation profile of pre-ingestive residue treatments are suitable alternative diets

GRAPHICAL ABSTRACT
Implementasi Metode Prototype Dalam Perancangan Sistem Informasi Upah Pasang Material Konstruksi
Authors: Gunawan Deni , Alfarizi Salman , Ichsan Nurul , Basri Hasan , Mulyawan Alif Rizqi 
Published: July 2022

Abstrak: PT. Cengkareng Permai merupakan produsen atau supplier pada sebuah proyek pembangunan perumahan, yang dapat menyediakan material dan jasa pemasangan pada material tersebut, sehingga pembayaran kepada mandor dilakukan oleh PT. Cengkareng Permai. Pembayaran upah pasang yang dilakukan masih secara manual menggunakan microsoft word, microsoft excel dan pencatatan manual pada buku, proses tersebut sering terjadi kesalahan pencatatan, tahap pengecekan oleh direktur memerlukan pencatatan ulang sehingga tidak efektif dan efisien. Berdasarkan latar belakang permasalahan tersebut, dibuatlah sebuah prototype sistem pembayaran upah pasang berbasis website yang dapat mencatat setiap informasi dari admin baja, direktur dapat langsung mengecek dan memberikan persetujuan serta bagian keuangan melakukan pembayaran. Metode pengembangan dan analisis menggunakan metode Prototype, dengan menganalisis kebutuhan pengguna, membuat mock-up dan menguji mock-up. Hasil dari penelitian ini adalah problematika, analisis kebutuhan pengguna, use case diagram, rancangan user interface, Entity Relationship Diagram serta hasil testing dari rancangan yang telah dibuat. Diharapkan sistem pembayaran upah pasang berbasis website dapat membantu PT. Cengkareng Permai.

Kata kunci: kontruksi, pembayaran, prototipe, sistem informasi

Abstract: PT Cengkareng Permai is a producer or supplier in a housing development project, which can provide materials and installation services; thus, PT Cengkareng Permai makes payments to artisans. The expense of post-wages is still done manually using Microsoft word, Microsoft excel, and manual recording on books; the process often occurs recording errors, and the stage of checking by the director requires re-recording, so it is not effective and efficient. Based on these problems' background, a website-based wage payment system prototype was created that can record any information from steel admins, directors can immediately check and give approval, and the finance department makes payments. The software development method used is the Prototype Method for the prototyping stages, namely analyzing needs, creating mock-ups, and testing mock-ups. The results of this study are problems, analysis of user needs, use case diagrams, user interface designs, Entity Relationship Diagrams and testing results from the designs that have been made. It is hoped that a website-based wage payment system can help PT. Cengkareng Permai.

Keywords: construction, information systems, payments, prototype
Nine-year trends of PM10 sources and oxidative potential in a rural background site in France
Authors: Borlaza Lucille Joanna , Weber Samuël , Marsal Anouk , Uzu Gaëlle , Jacob Véronique , Besombes Jean-Luc , Chatain Mélodie , Conil Sébastien , Jaffrezo Jean-Luc 
Published: July 2022

Abstract. Long-term monitoring at sites with relatively low
particulate pollution could provide an opportunity to identify changes in
pollutant concentration and potential effects of current air quality
policies. In this study, 9-year sampling of PM10 (particles with an aerodynamic diameter below 10 µm) was performed in a rural background site in France (Observatoire Pérenne de l'Environnement or OPE) from 28 February 2012 to 22 December 2020. The positive matrix factorization
(PMF) method was used to apportion sources of PM10 based on quantified
chemical constituents and specific chemical tracers analysed on collected
filters. Oxidative potential (OP), an emerging health metric that measures
PM capability to potentially cause anti-oxidant imbalance in the lung, was
also measured using two acellular assays: dithiothreitol (DTT) and ascorbic
acid (AA). The sources of OP were also estimated using multiple linear
regression (MLR) analysis. In terms of mass contribution, the dominant
sources are secondary aerosols (nitrate- and sulfate-rich) associated with
long-range transport (LRT). However, in terms of OP contributions, the main
drivers are traffic, mineral dust, and biomass burning factors. There is
also some OP contribution apportioned to the sulfate- and nitrate-rich
sources influenced by processes and ageing during LRT that could have
encouraged mixing with other anthropogenic sources. The study indicates much lower OP values than in urban areas. A substantial decrease (58 %
reduction from the year 2012 to 2020) in the mass contributions from the traffic factor was found, even though this is not clearly reflected in its OP contribution. Nevertheless, the findings in this long-term study at the OPE site could indicate effectiveness of implemented emission control policies, as also seen in other long-term studies conducted in Europe, mainly for urban areas.
Episodic N2O emissions following tillage of a legume–grass cover crop mixture
Authors: Bressler Alison , Blesh Jennifer 
Published: July 2022

Abstract. Nitrogen (N) fertilizer inputs to agricultural soils are
a leading cause of nitrous oxide (N2O) emissions. Legume cover crops
are an alternative N source that can reduce agricultural N2O emissions
compared to fertilizer N. However, our understanding of episodic N2O
flux following cover crop incorporation by tillage is limited and has
focused on single-species cover crops. Our study explores whether increasing
cover crop functional diversity with a legume–grass mixture can reduce pulse
emissions of N2O following tillage. In a field experiment, we planted
crimson clover (Trifolium incarnatum L.), cereal rye (Secale cereal L.), a clover–rye mixture, and a no-cover
control at two field sites with contrasting soil fertility properties in
Michigan. We hypothesized that N2O flux following tillage of the cover
crops would be lower in the mixture and rye compared to the clover
treatment because rye litter can decrease N mineralization rates. We
measured N2O for approximately 2 weeks following tillage to capture
the first peak in N2O emissions in each site. Across cover crop
treatments, the higher-fertility site, CF, had greater cover crop biomass,
2-fold-higher aboveground biomass N, and higher cumulative N2O
emissions than the lower-fertility site, KBS (413.4±67.5 vs. 230.8±42.5 g N2O-N ha−1; P=0.004). There
was a significant treatment effect on daily emissions at both sites. At
CF, N2O fluxes were higher following clover than the control 6 d after
tillage. At KBS, fluxes from the mixture were higher than rye 8 and 11 d
after tillage. When controlling for soil fertility differences between
sites, clover and mixture led to approximately 2-fold-higher N2O
emissions compared to rye and fallow treatments. We found partial support
for our hypothesis that N2O would be lower following incorporation of
the mixture than clover. However, treatment patterns differed by site,
suggesting that interactions between cover crop functional types and
background soil fertility influence N2O emissions during cover crop
decomposition.
Historical and future weather data for dynamic building simulations in Belgium using the regional climate model MAR: typical and extreme meteorological year and heatwaves
Authors: Doutreloup Sébastien​​​​​​​ , Fettweis Xavier , Rahif Ramin , Elnagar Essam , Pourkiaei Mohsen S. , Amaripadath Deepak , Attia Shady 
Published: July 2022

Abstract. Increasing temperatures due to global warming will influence
building, heating, and cooling practices. Therefore, this data set aims to
provide formatted and adapted meteorological data for specific users who
work in building design, architecture, building energy management
systems, modelling renewable energy conversion systems, or others
interested in this kind of projected weather data. These meteorological data
are produced from the regional climate model MAR (Modèle
Atmosphérique Régional in French) simulations. This regional model,
adapted and validated over Belgium, is forced firstly, by the ERA5 reanalysis,
which represents the closest climate to reality and secondly, by three Earth system models (ESMs) from
the Sixth Coupled Model Intercomparison Project database, namely,
BCC-CSM2-MR, MPI-ESM.1.2, and MIROC6. The main advantage of using the MAR
model is that the generated weather data have a high resolution (hourly data
and 5 km) and are spatially and temporally homogeneous. The generated weather
data follow two protocols. On the one hand, the Typical Meteorological Year
(TMY) and eXtreme Meteorological Year (XMY) files are generated largely
inspired by the method proposed by the standard ISO15927-4, allowing the
reconstruction of typical and extreme years, while keeping a plausible
variability of the meteorological data. On the other hand, the heatwave
event (HWE) meteorological data are generated according to a method used to
detect the heatwave events and to classify them according to three criteria
of the heatwave (the most intense, the longest duration, and the highest
temperature). All generated weather data are freely available on the open
online repository Zenodo (https://doi.org/10.5281/zenodo.5606983,
Doutreloup and Fettweis, 2021) and these data are produced within
the framework of the research project OCCuPANt
(https://www.occupant.uliege.be/ (last access: 24 June 2022)​​​​​​​ – ULiège).
Spatial assessment of probable recharge areas – investigating the hydrogeological controls of an active deep-seated gravitational slope deformation
Authors: Pfeiffer Jan , Zieher Thomas , Schmieder Jan , Bogaard Thom , Rutzinger Martin , Spötl Christoph 
Published: July 2022

Abstract. Continuous and slow-moving deep-seated landslides entail challenges for the effective planning of mitigation strategies aiming at the reduction of landslide movements. Given that the activity of most of these landslides is governed by pore pressure variations within the shear zone, profound knowledge about their hydrogeological control is required. In this context, the present study presents a new approach for the spatial assessment of probable recharge areas to better understand a slope's hydrogeological system. The highly automated geo-statistical approach derives recharge probability maps of groundwater based on stable isotope monitoring and a digital elevation model (DEM). By monitoring stable isotopes in both groundwater and precipitation, mean elevations of recharge areas can be determined and further constrained in space with the help of the DEM. The approach was applied to the Vögelsberg landslide, an active slab of a deep-seated gravitational slope deformation (DSGSD) in the Watten valley (Tyrol, Austria). Resulting recharge probability maps indicate that shallow groundwater emerging at springs on the landslide recharges between 1000 and 1650 m a.s.l. In contrast, groundwater encountered in wells up to 49 m below the landslide's surface indicates a mean recharge elevation of up to 2200 m a.s.l. matching the highest parts of the catchment. Further inferred proxies, including flow path length, estimated recharge area sizes, and mean transit times of groundwater, resulted in a profound understanding of the hydrogeological driver of the landslide. It is shown that the new approach can provide valuable insights into the spatial pattern of probable recharge areas where mitigation measures aiming at reducing groundwater recharge could be most effective.
Функционирование грамматических падежных форм русских существительных как стилистических приемов
Authors: Синьсинь Чжан 
Published: July 2022

Цель исследования – выявить стилистические приемы, функционирующие посредством грамматических падежных форм существительных в русской поэзии. Основными лингвистическими методами, использованными в исследовании, являются: описательный и аналитический, семантический и стилистический, дистрибутивный и количественный. Материал исследования представлен поэтическими произведениями XX века из Национального корпуса русского языка, а также отдельными поэтическими сборниками. Новизна исследования заключается в использовании стилистических приемов, представленных грамматическими падежными формами русских существительных. Полученные результаты могут быть использованы для дальнейшего развития концепции эстетики языка и речи.
Благодарности: исследование выполнено при финансовой поддержке провинции Цзилинь КНР в рамках проекта «Эстетические ресурсы морфологических средств (на материале поэзии В. Маяковского)» (Проект № 2020B216), «Эстетические ресурсы морфологических средств (на материале поэзии М. Цветаевой)» (Проект № 2020B216). JJKH20210150SK).