bluuebunny/crossref_metadata_2025_split huggingface dataset:
Global COVID-19 Vaccine Acceptance Rate: Systematic Review and Meta-Analysis
Authors: Mengistu Dechasa Adare , Demu Yohannes Mulugete 
Published: March 2022

Abstract
Background: A vaccine against COVID-19 is a vital tool in managing the current pandemic. It is becoming evident that an effective vaccine would be required to control COVID-19. Effective use of vaccines is important in reducing the pandemic and paving the way for an acceptable exit strategy. Therefore, the current review aimed to determine the global acceptance rate of the COVID-19 vaccine that is necessary for better management of the COVID-19 pandemic.Materials and Methods: This review was conducted under the Preferred Reporting Items for Systematic Reviews and Meta-Analysis protocols and considered the studies conducted on the acceptance and / or hesitancy rate of the COVID-19 vaccine around the world, and written in English language. Articles were searched using electronic databases including PubMed / MEDLINE, Scopus /Science Direct, Web of Science, Embase, CINAHL, and Google Scholars. The quality of the study was assessed using the Joanna Briggs Institute Critical Assessment tool for prevalence studies to determine the relevance of each included article to the study.Results: The global pooled acceptance rate of the COVID-19 vaccine was found to be 61.1% [95% CI: 53.8, 67.9% with a p-value <0.001]. Based on the subgroup analysis of the acceptance rate of the COVID-19 vaccine by publication year, the pooled acceptance rate of the COVID-19 vaccine reported by the studies published in 2020 and 2021 was 74.2 % [95% CI: 66.5, 80.7%] and 47.9% [95% CI: 37.8, 58.2%], respectively, resulting in an overall acceptance rate of 63.7% [95% CI: 56.8, 69.5%]. Based on the survey period, the study found the pooled acceptance rate of the COVID-19 vaccine from March to May 2020 [80.0% (95% CI: 68.8, 87.9%)], June to August 2020 [58.6% (95% CI: 38.0, 76.6%)] and September to December 2020 [46.3% (95% CI: 37.4, 55.8%)].Conclusions This review found the decreasing level of the acceptance rate of the COVID-19 vaccine. This finding indicated that even if the COVID-19 vaccine is developed, the issue of accepting or taking the developed vaccine and managing the pandemic may be difficult.
Treatment of Bronchial Anastomotic Fistula using Autologous Platelet-rich Plasma Post Lung Transplantation - A Case Report
Authors: Siddique Aisha , Sabbah Belal Nedal , Arabi Tarek Ziad , Shakir Ismail Mohammed , Abdulqawi Rayid , AlKattan Khaled , Ahmed Mohamed Hussein 
Published: March 2022

Abstract
Background: Bronchial anastomotic dehiscence is considered one of the most catastrophic early airway complications post-transplant. The presence of a partial dehiscence can also cause further complications such as a fistula between the bronchus and the pleural membrane. Platelet-rich plasma (PRP) is known to significantly enhance the healing process and is being used in the treatment of various conditions, however, so far, there are no reports of the use of PRP in the treatment of bronchial anastomotic dehiscence fistula.Case Presentation: We present a 37-year-old male, with non-cystic fibrosis bronchiectasis underwent bilateral lung transplantation. The patient developed partial dehiscence of the right bronchial anastomosis that was complicated by a small bronchopleural fistula. Two bronchoscopic applications of autologous platelet-rich plasma were carried out. Follow-up a few weeks later showed complete closure and healing of the fistula.Conclusions: This case report suggests that the treatment of post-lung transplant small bronchial anastomotic partial dehiscence fistula with PRP is safe and effective.
Multi-objective Optimization Model of Forest Spatial Structure Based on Dynamic Multi-Group PSO Algorithm
Authors: Wu Yuxin , Li Jianjun , Huang Jing , Qing Dongsheng , Ai Wei , Chi Peng , Li Keqin 
Published: March 2022

Abstract
The multi-objective optimization problem, as one of the most popular hotspots in the current research, is facing both a big opportunity and a great challenge. Multi-group particle swarm optimization is often used to solve multi-objective optimization problems, however, the multi-group particle swarm optimization algorithm is more commonly used in solving static multi-objective optimization problems and less frequently used in solving dynamic multi-objective optimization problems. In solving dynamic multi-objective optimization problems, the algorithm lacks the corresponding environment detection mechanism. In this work, Dynamic Multi-Group Particle Swarm Optimization Algorithm is proposed and verified to solve multi-objective optimization problems of forest spatial structure. The proposed algorithm introduces a new mechanism for environmental detection, which can sense the changes of the situated environment and make the multi-objective optimization results more suitable for the dynamic actual situation. The results show that the average generation distance (\(\stackrel{-}{GD}\)) of the proposed algorithm is less than 0.0753, and the average metric of maximum spread (\(\stackrel{-}{MS}\)) is greater than 0.9852. The spatial structure of the target forest has been optimized three times. The mingling intensity, volume, neighborhood comparison, and open ratio are increased by 40.6%, 2.5%, 18.9%, and 11.8%, respectively; while the competition index and angle index are decreased by 37.9% and 13.1%, respectively. Obviously, the various indicators of the forest improved by our scheme are better than those before optimization.
Subduction Age and Stress State Control on Seismicity in the NW Pacific Subducting Plate
Authors: Pino Nicola Alessandro , Convertito Vincenzo , Godano Cataldo , Piromallo Claudia 
Published: March 2022

Abstract
Intermediate depth (70–300 km) and deep (> 300 km) earthquakes have always been puzzling Earth scientists: their occurrence is a paradox, since the ductile behavior of rocks and the high confining pressure with increasing depths would theoretically preclude brittle failure and frictional sliding. The mechanisms proposed to explain deep earthquakes, mainly depending on the subducting plate age and stress state, are generally expressed by single parameters, unsuitable to comprehensively account for variations differences among distinct subduction zones or within the same slab. We analyze the Kurile and Izu-Bonin intraslab seismicity and detail the stress state along the subducted planes using the Gutenberg-Richter b-value. We demonstrate that, despite the slabs different properties (e.g., lithospheric age, stress state, dehydration rate), in both cases the deep earthquakes are restricted to depths characterized by equal age from subduction initiation and are driven by stress regimes affected by the persistence of the metastable olivine wedge.
Electromagnetic Wave Focusing with 2-D Gridded Parabolic Reflector Made of Parallel Circular PEC Wires at Oblique Incidence
Authors: Velichko Elena 
Published: March 2022

Abstract
We consider the two-dimensional (2-D) scattering of the TE- and TM-polarized plane electromagnetic waves from a discrete grid-like parabolic reflector consisting of parallel circular perfectly electrically conducting (PEC) wires at oblique incidence. Our analysis is performed in the exact formulation, fully taking into account the wave interactions between the wires. We use the method of separation of variables in the local cylindrical coordinate systems in combination with Graf’s addition formulas for cylindrical functions. The near field in the vicinity of the reflector is calculated at different angles of incidence. The dependences of the field amplitude at the maximum in the focal area and the position of this maximum on the angle of incidence are plotted. The far field scattered patterns, total scattering cross-sections and backward scattering cross-sections are calculated and discussed.
Facilitators for Retaining Men Who Have Sex With Men in Pre-exposure Prophylaxis Care in Real World Settings
Authors: Rogers Brooke G. , Sosnowy Collette , Zanowick-Marr Alexandra , Chan Phillip A. , Mena Leandro , Patel Rupa R. , Goedel William , Arnold Trisha , Chu Christina , Galipeau Drew , Montgomery Madeline , Curoe Kate , Underwood Ashley , Villalobos Jesus , Gomilia Courtney , Nunn Amy S. 
Published: March 2022

Abstract
Background: Pre-exposure prophylaxis (PrEP) can significantly reduce HIV acquisition especially among communities with high HIV prevalence, including men who have sex with men (MSM). Much research has been finding suboptimal PrEP persistence; however, few studies examine factors that enhance PrEP persistence in real-world settings. Methods: We interviewed 33 patients who identified as MSM at three different PrEP clinics in three regions of the U.S. (Northeast, South, Midwest). Participants were eligible if they took PrEP and had been retained in care for a minimum of 6 months. Interviews explored social, structural, clinic-level and behavioral factors that influencing PrEP persistence. Results: Through thematic analysis we identified the following factors as promoting PrEP persistence: (1) navigation to reduce out-of-pocket costs of PrEP (structural), (2) social norms that support PrEP use (social), (3) access to LGBTQ+ affirming medical providers (clinical), (4) medication as part of a daily routine (behavioral), and (5) facilitation of sexual health agency (belief).Conclusions: In this sample, persistence in PrEP care was associated with structural and social supports as well as a high level of perceived internal control over protecting their health by taking PrEP. Patients might benefit from increased access, LGBTQ+ affirming medical providers, and communications that emphasize PrEP can promote sexual health.
Stresses induced by one piece and two piece dental implants in All-on-4® implant supported prosthesis under simulated lateral occlusal loading: non linear Finite Element Analysis study
Authors: mohamed ahmed Mostafa abdelfattah , Askar Mohamed Gamal , Homossany Mahmoud El-Moutassim Bellah El 
Published: March 2022

Abstract
Background: Correct choice of the implant design and the occlusal scheme is important for the success of implant supported restorations. So, the aim of the current study was to find out the difference in the stresses induced by the one piece dental implants designed to be used in the All-on-4® concept and the conventional two piece ones under simulated lateral occlusal schemes using nonlinear Finite Element Analysis.Methods: Two Finite Element models of the maxilla, implants, and prostheses were designed according to the All-on-4® concept. In the model TP, two piece dental implants were placed while in the model OP one piece dental implants were used. Two loading scenarios were applied to each model; the first one simulated a group function occlusal scheme while the second scenario simulated a canine guided one. Results: The highest stress value was recorded in the model TP with the group function occlusion and the lowest stress value was in the model OP with the canine guidance occlusion.Conclusion: The one-piece dental implants can be concluded to induce less stress compared to the two piece dental implants when used in the All-on-4® implant supported prosthesis in the different lateral occlusal schemes. Canine guided occlusion can be concluded to cause lower stress values in comparison to the group function occlusal scheme..
Research on Gender-related Fingerprint Features, Extracting Fingerprint Features Using Autoencoder Networks for Gender Classification
Authors: Qi Yong , Qiu Menzhe , Lin Huawei , Chen Jiashu , Li Yanping , Lei Hongguang 
Published: March 2022

Abstract
Background: Fingerprint is an important biological feature of human body, which contains abundant biometric information.At present, the academic exploration of fingerprint gender characteristics is generally at the level of understanding, and the standardization research is quite limited. Methods: A robust approach is presented in this article, Dense Dilated Convolution ResNet Autoencoder, to extract valid gender information from fingerprints. By replacing the normal convolution operations with the atrous convolution in the backbone, prior knowledge is provided to keep the edge details and the global reception field can be extended. Results: The results were explored from three aspects: 1) The efficiency of the DDC-ResNet. 6 typical automatic feature extraction methods with 9 mainstream classifiers for a total of 54 combinations are evaluated on our dataset and provide unbiased experimental details. Experimental results demonstrate that the combination of our approach outperforms other combinations in terms of average accuracy and separate-gender accuracy. It reaches 96.5% for average and 0.9752(males)/0.9548(females) for separate-gender accuracy. 2) The effect of fingers. It is found that the best performance of classifying gender with separate fingers is achieved by the right ring finger. 3) The effect of specific features. Based on the observations of the concentrations of fingerprints visualized by our approach, it can be inferred that loops and whorls (level 1), bifurcations(level 2), as well as line shapes (level 3) are connected with gender. Finally, we will open source the dataset that contains 6000 fingerprint images. Conclusions: The results are demonstrated that autoencoder networks are a powerful method for extracting gender-specific features to help hide the privacy information of the user’s gender contained in the fingerprint. Our experiments also identified three levels of features in fingerprints that are important for gender differentiation, including loops and whorls shape, bifurcations shape, and line shapes.
Identification of a potential miRNA-mRNA regulatory network associated with the pathogenesis of cholestatic liver diseases
Authors: Song Shuailing , Li Xiao , Geng Chong , Guo Yaoyu , Wang Chunhui 
Published: March 2022

Abstract
Background
Cholestatic liver diseases (CLDs), including primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC), are common digestive diseases that may lead to liver fibrosis, cirrhosis, or even liver failure. However, ursodeoxycholic acid (UDCA), as the first-line drug therapy for PBC, achieves poor results among nearly half of patients. Furthermore, there are few effective ways to cure diseases other than liver transplantation at present. Therefore, it is essential to further explore the disease mechanism in order to find new therapeutic targets.
Methods
Gene Expression Omnibus (GEO) database (GSE159676) was used to screen differentially expressed hepatic miRNAs between PBC vs. control and PSC vs. control samples, and their interaction was considered as common miRNAs driving CLDs. A miRNA-mRNA network was then constructed based on predicted miRNA-targeted mRNAs. Then enrichment analysis was performed and protein-protein interaction (PPI) networks were constructed. In addition, these DEGs were also validated in models of cholestatic liver injury induced by α -isothiocyanate (ANIT) and bile duct ligation (BDL). Furthermore, the role of hub genes in cholestasis progression, UDCA response, and disease diagnosis were analyzed in GSE166867, GSE79850 and GSE119600, respectively.
Results
A total of 6 miRNAs and 437 mRNAs were identified as potential mediators in the pathophysiological processes of CLDs. Among them, 8 hub genes were identified (PTPRC, TYROBP, LCP2, RAC2, SYK, TLR2, CD53, and LAPTM5). The functional analysis confirmed that the molecular mechanism was strongly associated with Fc epsilon RI signaling pathway. Combining bioinformatics analysis with animal experimental results, miR-30e and miR-107 were the most significant DE-miRNAs. Additionally, activation of the 8 hub genes was observed in both ANIT-induced cholestasis model and time-course BDL model. Besides, an elevated hepatic SYK level was found in patients with UDCA inefficiency, and SYK in the blood may be an underlying diagnostic indicator for CLDs.
Conclusions
The present study constructed a miRNA-mRNA network of cholestatic liver diseases, and uncovered that the miR-30e, miR-107 and 8 hub genes could be involved in the pathogenesis of CLDs, providing potential therapeutic targets in CLDs.
Comparison of Body Image Perception of Young Women in the United States and Korea: From the National Health and Nutrition Examination Survey of the Two Countries
Authors: Kim Yoon-Sook , Kim Jin Kook , Cho Jae Hoon 
Published: March 2022

Abstract
Background
The purpose of this study is to investigate the differences in body image perception between young women in the United States and Korea.
Methods
This was a longitudinal study conducted using data from young women aged between 20 and 40 who participated in the National Health and Nutrition Examination Survey (1999–2018) of the US and Korea. "Overweight" body image perception with normal body weight was considered underestimation. Overweight or obesity with a "normal weight" or "underweight" body image perception is considered as overestimating.
Results
The percentage of young women who were overweight or obese was about 60% in the US and about 20% in Korea. Twenty years ago, the percentage of young women who overestimated their weight in the US was 30.3%, before steadily declining. In Korea, it was 25.8% before rising to more than 41.9% in 2008. Of the overweight women, 32.6% in the US and 15.7% in Korea underestimated their weight 20 years ago, but since then, the percentage has gradually increased in the US and declined in Korea.
Conclusions
Body image perception differed according to marital status and race. Young women in the US tend to underestimate their weight while in Korea they tend to overestimate it.
Adverse Events Following Immunization of ChAdOx1 nCoV- 19 Vaccine Among Health Care Workers of a Tertiary Care Hospital of North India
Authors: Dhamnetiya Deepak , Kumar Pankaj , Goel Shelesh Kumar , Jha Abhinav , Bharatwal Apoorv Amitabh , Singh Saurabh , Jha Ravi Prakash 
Published: March 2022

Abstract
Background
Adverse events following immunization (AEFI) of COVID-19 vaccines among healthcare workers (HCW) of North India remains underexplored. The prevalence of AEFI is usually directly related to willingness to get vaccinated among general population. In this study we report prevalence of AEFI and factors associated with the AEFI of the ChAdOx1 nCoV-19 vaccine (Covishield) among HCW of a tertiary care hospital of North India.
Methods
A cross-sectional study conducted in the month of June & July, 2021, HCW (N = 203) of 18 years and above who had received at least the 1st dose of Covishield vaccine were included after taking their informed consent. A semi-structured, pre-validated and pre-tested questionnaire was used to collect information. The Questionnaire was divided into five sections: socio-demographic profile, behavioural characteristics, past medical history, COVID-19 awareness and past infection and COVID-19 vaccine related information. Data was collected through interview schedule. Chi-squared test was applied to check the association of different factors with AEFI.
Results
In our study 73.89% participants suffered from at least one AEFI after 1st dose of vaccine, while 48.66% had at least one AEFI after 2nd dose. Females reported significantly high AEFI compared to males for both the doses of Covishield vaccine (p = 0.001, 0.000). We found significant association between occurrence of AEFI and occupation (1st dose p = 0.015), substance abuse (1st dose p = 0.002), diet (1st dose p = 0.016), and allergy (1st dose p = 0.027). Other significant findings were headache among HCW ≥ 40 years of age (2nd dose p = 0.034), systemic AEFI in participants with comorbidity (1st dose p = 0.020).
Conclusions
More AEFI were reported after first dose as compared to the second dose. AEFI were more among females after both the doses. Occupation, substance use, diet, and history of allergy were significantly associated with occurrence of AEFI. Awareness should be created among general population about the mild AEFI to reduce the vaccine hesitancy. There should be provision of follow-up of vaccinated person for early detection of possible AEFI. Proper advice should be given to vaccinated candidates about adverse events of self-medication after AEFI.
The Ant1 / panx1 pathway sensitizes patients with NAFLD to lifestyle interventions
Authors: Sun Bo , Lai Linying , Zhang Han , Yang Wenzhuo 
Published: March 2022

Abstract
Background: Different patients have different sensitivities to lifestyle interventions (LSI) and thus different outcomes (improved or unchanged). In the present study, we aim to find key markers that can identify patients sensitive to lifestyle interventions. Methods: Raw data were obtained from the Liver Clinic and Obesity Clinic of the Antwerp University Hospital that divided patients into LSI responders and non-responders based on the effectiveness of the intervention at the pathologic level. The limma / voom algorithm was used for difference analysis; Over representation analysis was used for functional enrichment analysis. Functional class scoring was used for gene set enrichment analysis. WGCNA and PPI / MCODE were used to identify valuable modules and genes. Western blot and immunohistochemistry were used for experimental validation.Results: Specific features of LSI responders were extracted based on differential expression and functional enrichment. The CIBERSORT and ESTIMATE algorithm reconfirmed that there were differences in the immune cell composition of LSI responders versus non-responders. Next, the WGCNA algorithm was used to integrate analyses of associations between immune cell phenotypes and genes. PPI and MCODE algorithms were used to screen for gene clusters with higher weights. The test set and validation set data were subjected to correlation analysis of the filtered genes to obtain the hub gene - ANT1. ANT1 was highly expressed in LSI responders, while it was lowly expressed in non-responders. Mechanistically, ANT1 responds to lifestyle intervention by activating Panx1, which is key to lesion improvement in LSI responder populations. Conclusions: In the study, we confirm that LSI responders populations respond to exercise intervention via the ANT1 / Panx1 pathway.