bluuebunny/crossref_metadata_2025_split huggingface dataset:
An artificial intelligence approach for modeling nachos developed from bhimkol banana (Musa balbisiana) blossom
Authors: Muchahary Sangita , Nickhil Chowdaiah , Deka Sankar Chandra 
Published: December 2022

AbstractThe study comprises the investigation of nutrition, phytocomponents, antioxidant activities, antibacterial activities, formulation, and optimization of nachos from underutilized bhimkol (Musa balbisiana) blossom by metaheuristic approach: optimal mixture designed artificial neural network coupled with particle swarm optimization (ANN‐PSO). The overall acceptability (OA) obtained from the sensory evaluation was taken as the output layer of the swarm optimization. Investigation showed bhimkol blossom (BB) as a good source of nutrition, phytocomponents such as carbohydrate (66.87 ± 0.20%), crude fiber (12.12 ± 0.28%), vitamin E (8.73 mg/g), and fatty acid consisting of monounsaturated (66.67%) and polyunsaturated (33.33%). The whole blossom showed the highest antioxidant at 82.77% in the 2,2‐diphenyl‐1‐picrylhydrazyl assay and major antibacterial activity against Salmonella typhi at IC50 25.21 ± 0.14 mg/ml. The optimum set of the parameter from ANN‐PSO for best nachos was obtained at OA of 8.9 in epoch 6 and showed high fracturability and crispiness. Principal component analysis among the sensory attributes of commercial, control, and BB nachos revealed that the taste and OA were majorly weighted towards component 1. The least significant difference was found between commercial and BB nachos. Nutrition rich nachos can be helpful in worldwide implementation in commercially profitable food industries.Practical ApplicationsUnderutilized wild bhimkol blossom (BB) is rich in nutrition, and phytocomponents along with significant antioxidant and antibacterial properties. The modeling of nachos by particle swarm optimization resulted in optimum set of parameters corn starch, wheat flour, BB, refined oil, and black pepper at 0.13, 0.39, 0.33, 0.66, and 0.26 g, respectively. Overall acceptability was positively affected by increased wheat flour exhibiting high fracturability and crispiness. This nutritious new product may possess other tremendous health benefits and have high consumer demand leading to profitable micro‐large food industries. This is also a sustainable approach to environmental loss and utilizing something demanding and good consumer acceptability.Novelty StatementUnderutilized wild bhimkol blossom is rich in nutrition, and phytocomponents along with significant antioxidant and antibacterial properties. Overall acceptability was positively affected by increased wheat flour exhibiting high fracturability and crispiness. This nutritious new product may possess other tremendous health benefits and have high consumer demand leading to profitable micro‐large food industries with excellent consumer acceptability.
An efficient CRISPR/Cas9 platform for targeted genome editing in rose (Rosa hybrida)
Authors: Wang Chengpeng , Li Yang , Wang Na , Yu Qin , Li Yonghong , Gao Junping , Zhou Xiaofeng , Ma Nan 
Published: December 2022

SUMMARYThe clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR‐related nuclease 9 (Cas9) system enables precise, simple editing of genes in many animals and plants. However, this system has not been applied to rose (Rosa hybrida) due to the genomic complexity and lack of an efficient transformation technology for this plant. Here, we established a platform for screening single‐guide RNAs (sgRNAs) with high editing efficiency for CRISPR/Cas9‐mediated gene editing in rose using suspension cells. We used the Arabidopsis thaliana U6‐29 promoter, which showed high activity for driving sgRNA expression, to modify the CRISPR/Cas9 system. We used our highly efficient optimized CRISPR/Cas9 system to successfully edit RhEIN2, encoding an indispensable component of the ethylene signaling pathway, resulting in ethylene insensitivity in rose. Our optimized CRISPR/Cas9 system provides a powerful toolbox for functional genomics, molecular breeding, and synthetic biology in rose.
Who Controls the Controller? People Reaction to Social Control Agent's Decisions about Organizational Misconduct
Authors: Cattani Gino , Clemente Marco , Durand Rodolphe , Mai Ke Michael 
Published: December 2022

AbstractSocial control agents (SCAs) discipline organizations and draw the line between appropriate organizational behaviour and misconduct. While prior research focuses on the SCA‐organization relationship, we theorize how a key audience (people) interacts with an SCA depending on its decisions to sanction or not organizational misconduct. Building on sociological and organizational research on social norms and their enforcement, we expect that people are more likely to agree with an SCA that sanctions a behaviour that violates rule‐based as opposed to value‐based norms. Violations of rule‐based norms generate more agreement because such norms are less ambiguous and ascertaining when they are violated is easier to establish. As people agree more with SCA decisions to sanction rule‐based violations, we expect that the propensity of people to resort to the SCA increases. We find support for our hypotheses with a survey, a series of experiments, and the analysis of complete data on complaints by UK citizens to the Advertising Standards Authority – the UK SCA on advertising – over the period 2007–10. Our paper contributes to research in organizational misconduct by showing how SCAs are both an evaluating entity and an evaluated one and by shedding light on how people co‐determine what an acceptable or unacceptable behaviour is. Our paper uniquely links macro‐ and micro‐level studies on corporate misconduct, putting centre stage that SCA's authority essentially depends on a key audience's agreement with the SCAs' underlying norms that underpin their decisions.
From job crafting to home crafting and back again: A shortitudinal study on the spillover between job and home crafting
Authors: Haun Verena C. , Mülder Lina Marie , Schmitz Anna‐Laura 
Published: December 2022

AbstractBuilding on the notion that successful crafting in one life domain spills over into another domain, we investigated the reciprocal effects between job and home crafting in 134 workers, using a shortitudinal study with a two‐week time lag. The results of cross‐lagged panel analyses suggested that there were reciprocal effects between the work and home domains of the crafting dimensions of increasing structural resources and reducing hindering social demands. Increasing social job resources lead to increasing social home resources, but the reverse is not true. No cross‐lagged effects were found for increasing challenging demands and reducing hindering structural job demands at work and home.
Time to update the sectional classification ofIlex(Aquifoliaceae): New insights fromIlexphylogeny, morphology, and distribution
Authors: Yang Yi , Jiang Lei , Liu En‐De , Liu Wei‐Li , Chen Li , Kou Yi‐Xuan , Fan Deng‐Mei , Cheng Shan‐Mei , Zhang Zhi‐Yong , Peng Hua 
Published: December 2022

AbstractResolving the infrageneric classification of species‐rich genera has been challenging in plant taxonomy.IlexL. is a subcosmopolitan genus with over 600 species of dioecious trees and shrubs. Many classification systems based on morphological data have been proposed during the past 250 years. However, these systems (such as Loesener's and Galle's systems) may not truly reflectIlex's evolutionary trajectories because most of those system's infrageneric hierarchies are not monophyletic. In this study, we reconstructed a phylogeny ofIlexL. comprising 15 moderately to highly supported clades using rigorously identified samples (202 species) and closely authenticated gene sequences of three nuclear genes [internal transcribed spacer (ITS), external transcribed spacer (ETS), andnepGS]. The newly generated phylogenetic tree resembles essentially that of the nuclear tree of Manen et al., but shows conspicuous topological differences with the phylogeny of Yao et al. Closely scrutinizing morphological variation and distributional patterns of 202 species, this study found that most lineages ofIlexidentified herein are well defined by a particular trait or a combination of morphological and distributional traits, displaying phylogeny–morphology–distribution conformity that has seldom been uncovered in previous studies. Given the general phylogeny–morphology–distribution conformity revealed in this genus, we put forward an updated sectional classification system forIlexthat temporarily contains 14 sections. The new classification will provide a robust framework for studying the evolution and diversification of this ecologically and economically important genus.
Integrated supervised consumption services and hepatitis C testing and treatment among people who inject drugs in Toronto, Canada: A cross‐sectional analysis
Authors: Greenwald Zoë R. , Bouck Zachary , McLean Elizabeth , Mason Kate , Lettner Bernadette , Broad Jennifer , Dodd Zoë , Nassau Tanner , Scheim Ayden I. , Werb Dan 
Published: December 2022

AbstractDespite the availability of publicly funded hepatitis C (HCV) treatment in Canada, treatment gaps persist, particularly among people who inject drugs. We estimate correlates of HCV care cascade engagement (testing, diagnosis, and treatment) among people who inject drugs in Toronto, Canada and examine the effect of accessing differing supervised consumption service (SCS) models on self‐reported HCV testing and treatment. This is a cross‐sectional baseline analysis of 701 people who inject drugs surveyed in the Toronto, Ontario integrated Supervised Injection Services (OiSIS‐Toronto) study between November 2018 and March 2020. We examine correlates of self‐reported HCV care cascade outcomes including SCS model, demographic, socio‐structural, drug use, and harm reduction characteristics. Overall, 647 participants (92%) reported ever receiving HCV testing, of whom 336 (52%) had been diagnosed with HCV. Among participants who reported ever being diagnosed with HCV, 281 (84%) reported chronic HCV, of whom 130 (46%) reported HCV treatment uptake and 151 (54%) remained untreated. Compared to those with no SCS use, participants who had ever injected at an integrated SCS model with co‐located HCV care had greater prevalence of both ever receiving HCV testing (adjusted prevalence ratio [aPR]: 1.12, 95% confidence interval [CI]: 1.02–1.24) and ever receiving HCV treatment (aPR: 1.67, 95% CI: 1.04–2.69). Over half of participants diagnosed with chronic HCV reported remaining untreated. Our findings suggest that integrated SCS models with co‐located HCV care represent key strategies for linkage to HCV care, but that more is needed to support scale‐up.
“A geography of the soul”: The displaced and the city in the work of Aleksandar Hemon
Authors: Peinado‐Abarrio Rubén 
Published: December 2022

AbstractBosnian‐American author Aleksandar Hemon is a self‐described diasporic writer interested in questions of identity, displacement, and exile. This article proposes an approach to the Hemonian displaced character based on two of the most influential conceptualisations of contemporary subjectivity: on the one hand, Rosi Braidotti's critical posthuman subject, a nomadic, multiple subject who embodies complexity, favours a dynamic notion of relationality, opposes the view of difference as inferiority, and embraces a situated and accountable perspective. On the other, Nicolas Bourriaud's radicant subject, a wanderer caught between an urge to connect with the other and the forces of dislocation and removal, between individuality and the standardisation enforced by globalisation, between exchange and imposition, between enrooting and uprooting. In Hemon, subject and city are essential constituents of an elaborate system—aimed at fostering bonding and building community—which has been damaged by forced migration and violence. The insistence with which the subject's process of becoming is grounded in an urban context invites a topopoetic reading of Hemon's fiction and nonfiction. The obsessive description of the war‐ravaged architecture of besieged Sarajevo turns home into what Maria Tumarkin calls a ‘traumascape’, a place marked by violence and loss. Meanwhile, Chicago is the non‐place that the refugee is forced to shape into a narrative space in order to build a human network and a personal infrastructure—what Hemon terms ‘a geography of the soul’. Ultimately, the phenomenological approach to the sensory experiences and material practices of the displaced person reveals how their predicament adds new meanings to urban wandering and the construction and appropriation of the city from below. The human and the urban are seen as operating in a complex network of interconnections and interdependencies, generating an ongoing state of encounter that allows Hemon and his characters to feel ‘placed’, both physically and metaphysically.
Indigenous diasporas in speculative fiction: Writing through estrangement
Authors: Eguíbar‐Holgado Miasol 
Published: December 2022

AbstractThis article explores diasporic dimensions of Indigenous experiences and narratives on Turtle Island, by looking at the Indigenous speculative fiction novelsThe Back of the Turtle(2014) by Thomas King,The Marrow Thieves(2017) by Cherie Dimaline, andThe Moon of the Crusted Snow(2018) by Waubgeshig Rice. The three evoke (post)apocalyptic or dystopic futures involving environmental crises and destruction. As Indigenous peoples have historically witnessed and experienced Apocalypse with colonization, both in the past and the present, speculative fiction provides fertile narrative ground to work with and through those legacies of devastation. I particularly focus on how these novels offer accounts of different forms of mobility that may be defined as diasporic. Often prompted by settler use and abuse of the land, and even the exploitation of Indigenous peoples as resource, the displacements and movements recorded in these stories trace routes of both oppression and resistance. These diasporas have fundamental political and historical significance, in that they highlight connections between past acts of colonialization and the violence of present‐day neoliberal capitalist practices. Simultaneously, speculating with estrangement in the form of the supernatural, apocalyptic or dystopic, serves as a mechanism to delineate decolonial stories of presence and survivance. These stories, while constantly referring to the past, also include motion towards possible better futures, countering Western notions of Indigenous peoples as static and futureless.
Narratives of the new diasporas: A theoretical approach
Authors: Alonso María Alonso , Fernández‐Melleda Bárbara 
Published: December 2022

AbstractThis introduction offers a survey of Border Studies and Diaspora Theory to contextualize the ways in which contemporary fictions of migration in the 21st century have reinterpreted classic paradigms. Literature has played a paramount role in illustrating many of the challenges of narrating the experience of migration. This role is the motivation for this Special Issue as it examines the literary mechanisms that engage with current social, economic, and political issues and shows how discourses on migration contest perspectives on concepts such as “mobility” or “space.” Thus after contextualizing “the Black Atlantic,” “diaspora space,” “third scenario,” “necropolitics” or “gore capitalism,” this introduction describes the contributors' diverse critical readings, which are presented and organized to illustrate the evolution of academic research around Diaspora Studies. The new avenues of research that 21st‐century migration has fostered bear witness to the complex and intricate phenomena of human mobility.
Experimental introgression in Drosophila: Asymmetric postzygotic isolation associated with chromosomal inversions and an incompatibility locus on the X chromosome
Authors: Poikela Noora , Laetsch Dominik R. , Kankare Maaria , Hoikkala Anneli , Lohse Konrad 
Published: December 2022

AbstractInterspecific gene flow (introgression) is an important source of new genetic variation, but selection against it can reinforce reproductive barriers between interbreeding species. We used an experimental approach to trace the role of chromosomal inversions and incompatibility genes in preventing introgression between two partly sympatric Drosophila virilis group species, D. flavomontana and D. montana. We backcrossed F1 hybrid females from a cross between D. flavomontana female and D. montana male with the males of the parental species for two generations and sequenced pools of parental strains and their reciprocal second generation backcross (BC2mon and BC2fla) females. Contrasting the observed amount of introgression (mean hybrid index, HI) in BC2 female pools along the genome to simulations under different scenarios allowed us to identify chromosomal regions of restricted and increased introgression. We found no deviation from the HI expected under a neutral null model for any chromosome for the BC2mon pool, suggesting no evidence for genetic incompatibilities in backcrosses towards D. montana. In contrast, the BC2fla pool showed high variation in the observed HI between different chromosomes, and massive reduction of introgression on the X chromosome (large X‐effect). This observation is compatible with reduced recombination combined with at least one dominant incompatibility locus residing within the X inversion(s). Overall, our study suggests that genetic incompatibilities arising within chromosomal inversions can play an important role in speciation.
Assessment of exercise‐induced hypoalgesia in chronic low back pain and potential associations with psychological factors and central sensitization symptoms: A case–control study
Authors: Patricio Philippe , Mailloux Catherine , Wideman Timothy H. , Langevin Pierre , Descarreaux Martin , Beaulieu Louis‐David , Massé‐Alarie Hugo 
Published: December 2022

AbstractIntroductionExercise is the most recommended treatment for chronic low back pain (CLBP) and is effective in reducing pain, but the mechanisms underlying its effects remain poorly understood. Exercise‐induced hypoalgesia (EIH) may play a role and is thought to be driven by central pain modulation mechanisms. However, EIH appears to be disrupted in many chronic pain conditions and its presence in people with CLBP remains unclear. As people suffering from chronic pain often exhibit psychological factors and central sensitization symptoms influencing pain perception, EIH might be associated with these factors.ObjectiveThe aim of this study is to compare the level of EIH between participants with and without CLBP following back and wrist exercises and to assess the associations between EIH, psychological factors, and symptoms of central sensitization (using the central sensitization inventory ‐ CSI) in CLBP.MethodTwenty‐eight participants with CLBP and 23 without pain were recruited. Pressure pain thresholds (PPT) were measured at 4 sites (2 bony sites = capitate, S1|2 muscle sites = wrist flexors, lumbar erector spinae) before and after each of two exercises (wrist flexion and lumbar extension). Exercise‐induced hypoalgesia was defined as percent change in PPT from pre‐ to post‐exercise. Participants with CLBP also completed questionnaires to measure psychological factors (e.g., kinesiophobia, catastrophizing, anxiety, and self‐efficacy) and symptoms of central sensitization (CSI), and correlations with EIH were calculated.ResultsAfter wrist exercise, EIH measured at the muscle sites was lower in the CLBP group compared with the pain‐free group (p = 0.047) but no differences were found at bony sites (p = 0.49). No significant differences for EIH were observed following back exercise at muscle sites (p = 0.14) or at bony sites (p = 0.65). Exercise‐induced hypoalgesia was not correlated with any psychological factors or with the CSI score.ConclusionThe lower EIH following wrist exercises may represent an alteration in pain modulation control in CLBP. However, psychological factors and central sensitization symptoms may not explain the differences observed.
Quantitative trait loci mapping of maize (Zea mays) ear traits under low‐phosphorus stress
Authors: Zhang Zhi , Shen Tao , Jiang Tao , Hu Xiaolan , Wen Min , Qiu Hongbo 
Published: December 2022

AbstractWe constructed an F2:3 population of 180 individuals from a cross between the maize genotypes 082 (high phosphorus use efficiency) and Ye107 (low phosphorus use efficiency). We used the population to perform quantitative trait loci (QTL) mapping for eight ear traits (ear diameter [ED], ear length [EL], ear weight [EW], ear kernel weight [EKW], row number per ear [ERN], bald tip length [BTL], kernel number per row [RKN] and number of seeds per plant [NSP]) in three low‐phosphorus environments. A total of 36 QTL for ear traits were detected in at least one of three single environments and were located on all maize chromosomes except for chromosome 10; the explained phenotypic variation ranged from 5.91% to 12.80%. The QTL JAqEKW5‐1, JAqEL3‐1, JAqEW1‐1, JAqBTL1‐1 and JAqNSP5‐2 were identified and stably expressed in single‐environment and joint‐environment analyses. Some novel QTL that have not been reported previously were also detected. Most of the identified QTL had stable effects in all low‐phosphorus environments, suggesting that they may be useful for molecular breeding to develop low‐phosphorus tolerant maize varieties.
Gastrostomy tube feeding in epidermolysis bullosa: A multi‐center assessment of caregiver satisfaction
Authors: Kleinman Elana P. , Reimer‐Taschenbrecker Antonia , Haller Courtney N. , Paller Amy S. , Levy Moise L. , Eichenfield Lawrence F. 
Published: December 2022

AbstractBackground/ObjectivesGastrostomy tubes (G‐tubes) are a feasible intervention for nutritional support in patients with epidermolysis bullosa (EB) who suffer from gastrointestinal involvement. However, some parents may be apprehensive about this surgical intervention. The purpose of this study is to assess caregiver satisfaction and experiences after G‐tube insertion in children with EB.MethodsNine institutions sent an anonymous 89‐item online questionnaire to caregivers of patients with EB and active G‐tubes during an 8‐week study period. The questionnaire consisted of eight sections and was formatted with multiple choice, Likert scales, dichotomous scales (yes/no), and free text.ResultsTwenty caregiver surveys were completed. All caregivers were parents (100%). The average age of G‐tube placement was 2.7 years (SD: 2.1, range 0–8) and duration of the G‐tube utilization was an average of 12.0 years (SD: 7.8, range 1–25). EB subtypes were dystrophic (n = 15/20, 75%), junctional (n = 3/20, 15%), and simplex (n = 2/10, 10%). Almost all caregivers (n = 18/20, 90%) reported high levels of satisfaction with G‐tube management (scores > 20 on the modified SAGA‐8 scale). More than half of caregivers (n = 12/20, 60%) reported that, retrospectively, they would have desired earlier adoption of the G‐tube. Caregivers rated mealtimes as more enjoyable and easier both for themselves and the individual with EB post‐G‐tube placement.ConclusionThe survey demonstrates a high rate of satisfaction for G‐tube use among caregivers of patients with EB across varying ages and household settings. The free‐text responses provide unique insight into caregiver's individual experiences regarding G‐tubes to be considered for future studies.