bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bereavement Experiences of Families in the Cardiac Intensive Care Unit
Authors: Erikson Alyssa E. , Puntillo Kathleen A. , McAdam Jennifer L. 
Published: January 2022

Background
Losing a loved one in the intensive care unit is associated with complicated grief and increased psychologic distress for families. Providing bereavement support may help families during this time. However, little is known about the bereavement experiences of families of patients in the cardiac intensive care unit.

Objective
To describe the bereavement experiences of families of patients in the cardiac intensive care unit.

Methods
In this secondary analysis, an exploratory, descriptive design was used to understand the families’ bereavement experiences. Families from 1 cardiac intensive care unit in a tertiary medical center in the western United States participated. Audiotaped telephone interviews were conducted by using a semistructured interview guide 13 to 15 months after the patient’s death. A qualitative, descriptive technique was used for data analysis. Two independent researchers coded the interview transcripts and identified themes.

Results
Twelve family members were interviewed. The majority were female (n = 8, 67%), spouses (n = 10, 83%), and White (n = 10, 83%); the mean age (SD) was 58.4 (16.7) years. Five main themes emerged: (1) families’ bereavement work included both practical tasks and emotional processing; (2) families’ bereavement experiences were individual; (3) these families were resilient and found their own resources and coping mechanisms; (4) the suddenness of a patient’s death influenced families’ bereavement experiences; and (5) families’ experiences in the intensive care unit affected their bereavement.

Conclusions
This study provided insight into the bereavement experiences of families of patients in the cardiac intensive care unit. These findings may be useful for professionals working with bereaved families and for cardiac intensive care units considering adding bereavement support.
Role of Hyperbilirubinaemia as a Predictor of Complicated Appendicitis in Paediatric Population
Authors: Koirala Dinesh Prasad , Gupta Amit Kumar , Dahal Geha Raj , Shrestha Bibek Man , Shrestha Suraj , Neupane Subita , Pokharel Rameshwar Prasad 
Published: January 2022

Background:
Acute appendicitis is a common surgical emergency amongst the paediatric population. Available diagnostic tools are focussed to make a diagnosis of acute appendicitis. A definitive predictive factor for the diagnosis of complicated appendicitis is lacking. Thus, this aims to analyse hyperbilirubinaemia as a predictor of complicated appendicitis amongst the paediatric population.

Materials and Methods:
A prospective observational study was conducted in a tertiary hospital from November 2018 to October 2019. All children undergoing emergency appendectomy were included in the study. Preoperatively, patients were evaluated clinically, and routine investigations including total and direct serum bilirubin were sent. All patients were grouped as ‘simple appendicitis’ or ’complicated appendicitis’ based on intra-operative and histological findings. Bilirubin level was compared between these groups and analysed.

Results:
A total of 52 children fulfilling the inclusion criteria were included. The mean age was 13.2 ± 4.2 years, and the male: female ratio was 2.1:1. Thirty-four (65.4%) had simple appendicitis and 18 (34.6%) had complicated appendicitis. Total bilirubin was 23.83 ± 5.94 mmol/L in the complicated appendicitis group and 13.15 ± 3.29 mmol/L in the simple appendicitis group. Direct bilirubin was 5.28 ± 2.22 mmol/L in complicated appendicitis and 2.62 ± 0.83 mmol/L in simple one. Both total and direct bilirubin were significantly high in the complicated group (P < 0.001) compared to the simple appendicitis group. On the Receiver operating curve (ROC), the best cutoff value for total and direct bilirubin was 21 and 5.5 mmol/L, respectively. The sensitivity and specificity of total and direct bilirubin were 72.2%, 100%, and 61.1%, and 85.3%, respectively.

Conclusion:
It is concluded that hyperbilirubinaemia is a good predictor for paediatric complicated appendicitis.
A 5-Year Multidisciplinary Care Outcomes in Children with Wilms’ Tumour Managed at a Tertiary Centre
Authors: Alakaloko Felix M. , Akinsete Adeseye M , Seyi-Olajide Justina O. , Joseph Adedayo O , Elebute Olumide O. , Ladipo-Ajayi Oluwaseun A. , Odubanjo M. Olatokunboh , Olowoyeye Omodele A. , Ademuyiwa Adesoji O. , Temiye Edamisan O. , Akinsulie Adebola A , Bode Christopher O. 
Published: January 2022

Background:
Over the last two decades, there has been significant improvement in the outcomes of children with Wilms’ tumour (WT) in high income countries (HICs) with approximately 85% survival rate globally. This is partly attributable to a multi-disciplinary team approach to care and the evolution of more robust treatment measures. A previous review in our centre prior to multi-disciplinary team shows a survival rate of 31.48%, However, the survival rates from low- and middle-income countries are still low when compared to HICs due to delays in access to care at all levels, poor to non-existent health insurance coverage, limited workforce resources, weak health-care systems and infrastructure. The aim of this study is to determine the impact of a multi-disciplinary team approach on the treatment outcomes of children with WT.

Methodology:
This is a 5-year retrospective review of all patients managed with WT at the Lagos University Teaching Hospital, Lagos, Nigeria. Information was extracted from the patients’ case notes, operation notes and ward admission records. The data were analysed with SPSS 25, and P < 0.05 was considered to be statistically significant.

Results:
Forty patients were included in the study; male to female ratio was 1.6:1. The disease occurred in the right kidney in 23 patients (57.5%) and on the left in 17 patients (42.5%). The average duration of symptoms before presentation was 3.6 months (range 1–7 months), majority of patients presented with abdominal masses and were assessed as per unit protocol with abdominal Computerized tomography scan, chest X-ray and abdominal ultrasound scan to assign the patient International Society of Paediatric oncology regimen. The predominant stage at surgery was Stage III 26 (65%), while Stage IV was 9 (22.5%). Morbidity after chemotherapy was 10 (25%). Twenty-five patients (63%) completed chemotherapy while 15 patients (37%) started chemotherapy but defaulted midway. The 5-year survival rate was 75%. Increasing age and male sex were associated with reduced odds of mortality; however, this was not statistically significant. Increased duration of treatment, being treated with chemotherapy alone, as well as advanced tumour stage and histology were associated with increased odds of mortality, however, this was not statistically significant.

Conclusion:
The development of an institutional WT treatment pathway involving a multidisciplinary team has resulted in improved outcomes. There is need for increased community awareness to improve the time to presentation.
Annular Pancreas in Neonates; Case Series and Review of Literatures
Authors: Ali Almoamin Haithem Hussein , Kadhem Sadik Hassan , Saleh Ansam Mahmood 
Published: January 2022

Background:
The annular pancreas is a rare congenital disorder of the pancreas first recognized in 1818. It is believed to result from faulty rotation of the ventral pancreatic bud in its course around the posterior aspect of the duodenal anlage. The duodenum is encircled and might be obstructed by normal pancreatic tissue. The management of the annular pancreas is still developing and under revision.

Case Presentation:
Six cases of neonatal intestinal obstruction secondary to the annular pancreas diagnosed, operated on, and involved in our study. Age, gender, maturity, age at referral, birth weight, clinical presentation, imaging findings, associated congenital anomalies, treatment, complications, and hospital stay were all studied. Polyhydramnios is found in 3 cases (50%). Down syndrome was diagnosed in one case. One patient has associated malrotation. Symptoms started earlier within the first 24 hours. Vomiting was bile stained in 4 cases (66.7%). Passing meconium, sometimes frequent, does not exclude the annular pancreas. Most patients show double bubbles sign on plain abdominal X-ray. All six neonates were treated with duodenoduodenostomy with excellent results. Survival was 100% and complications were minimum.

Conclusion:
The annular pancreas, although rare, is an important cause of neonatal duodenal obstruction. The accurate diagnosis is usually performed during laparotomy. Vomiting may contain bile or not, furthermore, passing meconium does not exclude this condition. The best and the excellent surgical option is diamond duodenoduodenostomy. This case series might be added to the registered cases of the annular pancreas to standardize the method of diagnosis and to define the best management.
Paediatric Osteoarticular Infections Caused by Staphylococcus aureus Producing Panton–Valentine Leucocidin in Morocco
Authors: Moutaouakkil Kaoutar , Abdellaoui Hicham , Arhoune Btissam , Atarraf Karima , El Fakir Samira , Yahyaoui Ghita , Mahmoud Mustapha , Afifi Moulay Abderrahmane , Oumokhtar Bouchra 
Published: January 2022

Objective:
We aimed to estimate the prevalence of Staphylococcus aureus producing Panton–Valentine leucocidin (PVL) isolated from children diagnosed with osteoarticular infections (OAIs), and to examine risk factors and clinical features.

Methods:
This prospective study was conducted from January 2017 to December 2018. All hospitalised children diagnosed with S. aureus OAI are included. Blood cultures, articular fluids, synovial tissues and/or bone fragments were collected for bacteriological culture. Antimicrobial susceptibility tests were determined by disk diffusion method. Genes encoding methicillin resistance (mecA) and PVL virulence factors (luk-S-PV and luk-F-PV) were detected by multiplex polymerase chain reaction. The demographic, clinical, laboratory, radiographic and clinical features were reviewed prospectively from medical records.

Results:
A total of 37 children with S. aureus OAIs were included, 46% of them have PVL-positive infection and 70.6% were male. The mean age was 8.12 years (±4.57), and almost were from rural settings (76.5%). Children with Staphylococcus aureus producing Panton–Valentine leucocidin (SA-PVL) were significantly associated with type of infection (P = 0.005), location of infection (P = 0.037) and abnormal X-ray (P = 0.029). All strains SA-PVL+ are sensitive to methicillin, but one strain SA-PVL negative was methicillin-resistant S. aureus, confirmed by gene mecA positive.

Conclusion:
The prevalence of S. aureus infections producing PVL toxin was high in OAIs amongst Moroccan children, mainly due to methicillin-susceptible S. aureus. Type and location of infections and abnormal X-ray were significantly associated with SA-PVL. Routine diagnostic testing of PVL-SA, continuous epidemiological surveillance and multidisciplinary management of OAI is essential to prevent serious complications.
Evaluation of Maternal Preferences for Neonatal Male Circumcision in Enugu Nigeria
Authors: Ezomike Uchechukwu Obiora , Chinawa Josephat Maduabuchi , Enebe Joseph T. , Ezugwu Euzebus Chinonye , Aniwada Elias C. , Ezomike Nkeiruka Elsie , Chinawa Awoere T. , Ekenze Sebastian Okwuchukwu 
Published: January 2022

Background:
Although circumcision in male neonates is one of the most common procedures performed in neonatal surgery, mothers’ preferences concerning the aspects of circumcision are not well-known. Since mother is the likely parent to present child for circumcision, her preferences should be given adequate consideration.

Objectives:
The objective of this study is to evaluate maternal preferences for neonatal male circumcision in Enugu.

Methodology:
A cross-sectional study where questionnaire was distributed by the researchers to consenting pregnant women attending antenatal clinics in two teaching hospitals in Enugu. Data analysis was performed using the SPSS. The results presented as means, percentages and tables. Test for significance was done using the Chi-square test.

Results:
Four hundred and sixty-one pregnant women participated in the study. Ninety-five percent (438/461) wanted circumcision and 83.5% (385/461) wanted it on or before the 8th day of life. The reasons were cultural/religious in 69% (302/447). Fifty-four percent (250/461) had no preferences as to methods, but for those who had, Plastibell was most preferred method in 28% (129/461) while 76% (235/309) preferred circumcision to be done in hospital. In 49.2% (227/461) preferred personnel were nurses but 79.6% (367/461) wanted doctors to attend to post-circumcision complications. In 79.2% (365/461), mothers will not insist on the use of anaesthesia for circumcision. Mothers with circumcised husbands were significantly more willing to circumcise a male child (P = 0.0018). Higher educational status of mother was significantly related to willingness to insist on the use of anaesthesia (P = 0.046) and use of analgesics after circumcision (P = 0.001).

Conclusions:
Most mothers prefer neonatal male circumcision by nurses, while preferring doctors for post-circumcision complications. These choices are not affected by parents' educational status. Mothers with circumcised husbands accepted circumcision more than those with uncircumcised husbands. Higher maternal education encourages anaesthesia during circumcision and post-circumcision analgesia.
Albumin Haemoglobin Index
Authors: Silahli Musa , Tekin Mehmet 
Published: January 2022

Aim:
The aim of this study was to evaluate the mortality and morbidity of infants <1 year of age with intestinal obstruction requiring surgical intervention and to investigate the factors affecting mortality and hospital length of stay in paediatric surgery, including albumin-haemoglobin index.

Patients and Methods:
The records of gastrointestinal paediatric surgeries in the past 10 years of patients who were <1-year-old at Baskent University Konya Hospital were obtained from the hospital and retrospectively studied. Patient characteristics, especially the relationship between albumin haemoglobin index (AHI) and hospital duration and mortality, were examined. According to the surgical areas, it also subjected this relationship to further analysed in subgroups.

Results:
There were 144 cases who fulfilled the inclusion criteria. Pre-operative serum AHI was analysed using receiver operating characteristics (ROC) curve analyzes. In the ROC analysis, AHI had a diagnostic value in predicting case discharge rates (area under the curve: 0.755, P = 0.001). When the cut-off point was set at 46.18, the sensitivity of the test was 57.5% and the sensitivity for predicting survival was 84%. In the logistic regression model to estimate survival, the odds ratio of AHI was 1.063 (confidence interval: 1.020–1.108, P = 0.004). In subgroup analyzes, AHI positively predicted survival in the NEC group and in the other group. In a linear regression model analysing the effect of AHI on hospital stay of length, AHI explained 10% of the variance in the hospital stay of length variable and significantly and negatively influenced the hospital length variable (β = −0.319, P = 0.05). In the linear regression model for subgroup analyzes, AHI significantly and negatively predicted hospital length of stay in the NEC and pyloric surgery groups, but positively predicted hospital length of stay in the perforation group.

Conclusion:
The AHI can be used as a valuable marker to predict the likelihood of discharge and length of hospital stay in paediatric surgical cases <1-year-old.
Evaluation of pharmacy students’ knowledge and perceptions of transitions of care services
Authors: Yang Tianrui , Wooster Jessica 
Published: January 2022

Introduction: Studies support incorporation of pharmacists and pharmacy students to improve health and financial outcomes during transition of care (TOC). Standardisation of TOC educational training is currently lacking in pharmacy curricula.
Methods: This study employed a cross-sectional, descriptive study with a convenience sample at one college of pharmacy. Students participated in an anonymous Qualtrics survey including items on TOC service understanding and educational training. Results are reported as means and standard deviation for continuous data; frequencies and percentages for categorical data.
Results: Of 116 survey responses, 112 provided informed consent. Seventy-eight percent of respondents stated they have learned about TOC and 66% felt they understood what TOC entails. When asked to identify disease states commonly targeted for TOC, 77% responded incorrectly to this item. When asked to select TOC clinical activities, 66% incorrectly selected medication dispensing. Ninety-six percent of respondents replied that additional educational training on TOC would be beneficial.
Conclusion: There is a discrepancy in students’ perception of TOC services with their actual knowledge of TOC services based on survey responses.
Explaining the influence behind Malaysia’s pharmacy students’ career choices within the pharmaceutical industry
Authors: Ibrahim Nur Farah Diyaanah , Hatah Ernieda , Aziz Siti Azdiah Abd , Hisham Shairyzah Ahmad , Ngadimon Irma Wati , Farukh Muhammad Junaid , Asmadi Mohd Fadli Mohd 
Published: January 2022

Objective: The pharmaceutical industry has been portrayed as a promising sector for pharmacy graduates. Nonetheless, little is known about pharmacy students’ preferences, knowledge, and attitudes toward careers in the pharmaceutical industry, as well as the factors that may influence them.
Method: A self-developed questionnaire was administered to pharmacy students in public and private universities in Malaysia from October to November 2018 via online platforms.
Results: Only 38.8% out of 433 students who completed the survey stated their preference for working in the pharmaceutical industry. The mean (SD) of knowledge, perceived syllabus, and attitudes related to pharmaceutical industry career preferences were 8.73 (1.77) (full score of 12), 28.50 (5.83) (full score of 40), and 30.59 (4.32) (full score of 50), respectively. Students from private universities, those in years one and three of study, and those with higher attitude scores were more likely to choose the pharmaceutical industry as their career option.
Conclusion: Increasing exposure to pharmaceutical industry careers that involve patient contact and clinical knowledge application is needed to improve students’ attitudes toward pursuing a career in this field.
Virtual OSCE: Experience and challenges with a large cohort of pharmacy students
Authors: Zulkifly Hanis Hanum , Zaki Izzati Abdul Halim , Karuppannan Mahmathi , Mohd Noordin Zakiah 
Published: January 2022

In response to the inability to conduct conventional face-to-face objective structured clinical examination (OSCE) due to the COVID-19 lockdown, this study explored options to design virtual OSCE (vOSCE) that meets the objectives and standards of effective competency-based assessment for a large cohort of pharmacy students. The vOSCE required advanced planning of the actual assessment and technical conduct. The development of a master plan consisting of the types of competencies to test, topics and number of cases, and assessment rubrics, guided the team members to develop an adequate OSCE assessment module. Technical aspects included recruitment of examiners, simulated patients (SP), technical support, and a platform for vOSCE. The main challenges were to ensure well-ordered vOSCE and a stable internet connection for examiners, SP, and students. Google Meet was utilised due to its functionality, familiarity, and low internet consumption to all parties involved. Feedback was obtained from stakeholders to improve future OSCE conduct.
Dampak Begadang Terhadap Kesehatan Mental Remaja Mojosari
Authors: Agung Agung Nugraha Nursya'bana 
Published: January 2022

Abstrak
Remaja merupakan proses peralihan dari anak anak menuju dewasa. Pada masa ini seseorang mengalami perubahan emosi yang signifikan dan tidak stabil. Biasanya remaja suka melakukan hal hal seenaknya sendiri tanpa mempertimbangkan dampak panjangnya contohnya seperti sering melakukan begadang. Bila begadang terlalu sering maka seseorang tersebut dapat mengalami berbagai gangguan kesehatan tubuh dan berpengaruh juga ke kesehatan mentalnya. Penelitian ini bertujuan untuk mengetahui dampak-dampak dari Begadang Terhadap kesehatan Mental Remaja serta memberikan jalan keluar dari gangguan untuk remaja yang terjebak dalam siklus begadang dan tidak dapat kembali ke jam normalnya
Kata Kunci: Remaja, Begadang, Kesehatan Mental

Abstract
Adolescence is a process of transition from children to adults. At this time a person experiences significant emotional changes and is unstable. Usually, teenagers like to do things on their own without considering the long-term impact, for example, often staying up late. If you stay up too often, a person can experience various health problems and affect their mental health. This study aims to determine the impacts of staying up late on the mental health of adolescents and to provide a way out of the disorder for adolescents who are trapped in the cycle of staying up late and unable to return to their normal hours.
Keywords: Teenagers, Staying Up Late, Mental Health
IMPLEMENTASI PEMBELAJARAN TEMATIK DALAM MEMBENTUK KARAKTER PESERTA DIDIK
Authors: Masna Masna intan , Fatmawati Fatmawati , Rahman Hardianto 
Published: January 2022

Mendeskripsikan implementasi desain pembelajaran tematik, proses pembelajaran tematik dan juga evaluasi pembelajaran tematik. Penelitian ini merupakan penelitian kualitatif deskriptif dengan menggunakan pendekatan fenomenologi. Pengumpulan data di dalam penelitian ini di lakukan dengan cara observasi, wawancara mendalam dan dokumentasi. Seluruh data yang telah di peroleh di analisis kemudian di sajikan dan ditarik kesimpulan. Hasil dari penelitian ini menunjukkan bahwa: 1) desain pembelajaran tematik dalam membentuk karakter peserta didik yang dilakukan oleh guru di MIN 3 Sinjai adalah dengan memetakan dahulu kompetensi dasar dengan menetapkan tema apa yang akan dibahas dan menjabarkannya ke dalam indikator, kemudian menyusun silabus dan disusun menjadi Rencana Pelaksanaan Pembelajaran (RPP), untuk pembuatan RPP masih dibuat di Kelompok Kerja Guru (KKG). 2) pelaksanaan pembelajaran tematik dalam membentuk karakter peserta didik menekankan pada aspek kognitif, afektif dan psikomotorik sehingga pelaksanaan pembelajaran menyeimbangkan teori dan praktiknya. Selain itu setiap pembelajaran tematik diselipkan keterampilan-keterampilan untuk lebih menggali kreatifitas peserta didik dan pertumbuhan nilai-nilai karakter. 3) evaluasi pembelajaran tematik dalam membentuk karakter peserta didik menggunakan berbagai macam variasi, mulai dari catatan buku kendali maupun melalui pengamatan secara langsung yang dilakukan oleh guru. Evaluasi pembelajaran di sekolah ini setiap guru mempunyai buku catatan atau buku kendali yang fungsinya untuk mengetahui perkembangan pengetahuan dan perilaku anak, perilaku terhadap orang di sekitarnya, dan perilaku dalam hal belajar. 4) karakter peserta didik yang terbentuk melalui pembelajaran tematik bisa di lihat dari kebiasaan siswa dalam mengikuti shalat Zduhur berjamaah, pelaksanaan upacara bendera tiap hari senin, pelaksanaan senam setiap hari jumat dan juga kerja bakti yang dilakukan sekali dalam seminggu.