TOXICITY TEST OF THE CROWN OF GOD STEMPS (Phaleria macrocarpa (Scheff.) Boerl.) AGAINST Culex sp. Larvae
Authors: Nasution Ali Napiah , Ulina Yunike Yessica 
Published: July 2022

Abstrak Mahkota dewa (Phaleria macrocarpa (Scheff.) Boerl.) mampu tumbuh dan berkembang di negara beriklim tropis seperti Indonesia. Beberapa penelitian sebelumnya dikatakan mahkota dewa memiliki banyak kandungan senyawa kimia salah satunya adalah minyak atsiri yang berpotensi membunuh nyamuk. Kebaruan dalam penelitian ini adalah uji toksisitas batang tumbuhan mahkota dewa (phaleria macrocarpa (scheff.) boerl.) terhadap larva nyamuk culex sp. Populasi Culex sp. lebih banyak dari jenis nyamuk lainnya. Penelitian ini bertujuan melihat efek toksik dari ekstrak batang mahkota dewa terhadap larva nyamuk Culex sp. dalam konsentrasi 5%, 10%, 15% dan 25% berdasarkan waktu pengamatan (0 detik, 30 detik, 1 menit, 5 menit, 15 menit, 30 menit, 1 jam dan 2 jam). Rancangan penelitian the post test only controlled group design dengan subjek penelitian yang digunakan larva nyamuk Culex sp.. Kedalam cawan petri yang berisi ekstrak batang mahkota dewa dengan berbagai tingkat konsentrasi (0%, 5%, 10%, 15% dan 25%) ditambahkan larva nyamuk Culex sp.. Metode Mann-Whitney digunakan untuk menganalisa data penelitian, hasilnya mengatakan bahwa perbedaan persentase larva nyamuk Culex sp. yang mati setelah diberi perlakuan ekstrak batang mahkota dewa setelah waktu pengamatan 1 jam (Nilai P = 0,001) dan 2 jam (Nilai P = 0,002). Pada penelitian ini kesimpulan yang didapatkan adalah efek toksik yang efektif terjadi pada konsentrasi 25% setelah 1 jam diberi perlakuan. Kesimpulan esktrak batang tumbuhan mahkota dewa (Phaleria macrocarpa (Scheff.) Boerl.) mempunyai efek toksik untuk membunuh larva nyamuk Culex sp. Kata Kunci : Larva Nyamuk Culex sp; Mahkota dewa (Phaleria macrocarpa (Scheff.) Boerl.); Toksisitas. Abstract The crown of god (Phaleria macrocarpa (Scheff.) Boerl.) able to grow and develop in tropical countries such as Indonesia. Some previous studies have said the crown of the god has a lot of chemical compounds, one of which is essential oil that has the potential to kill mosquitoes. The novelty in this research is the toxicity test of the stem of the Mahkota dewa plant (Phaleria macrocarpa (scheff.) boerl.) against the larvae of the Culex sp. Population of Culex sp. More than any other type of mosquito. Culex sp. The study aimed to look at the toxic effects of the crown of god extract on the Culex sp. larvae in concentrations of 5%, 10%, 15% and 25% based on observation time (0 seconds, 30 seconds, 1 minute, 5 minutes, 15 minutes, 30 minutes, 1 hour and 2 hours). The post test only controlled group design research design with research subjects used Culex sp. larvae. Into the petri dish containing extract of the crown of god stem with a concentration level (0%, 5%, 10%, 15% dan 25%) added Culex sp. larvae. Mann- Whitney method was used to analyze the research data, the results said that the difference in the percentage of Culex sp. larvae that died after being treated with the extract of the crown of god stem after an observation time of 1 hour (P value = 0.001) and 2 hours (P value = 0.002). In this study, the conclusion obtained was that the effective toxic effect occurred at a concentration of 25% after 1 hour of treatment. Conclusion: The stem extract of the crown of the god (Phaleria macrocarpa (Scheff.) Boerl.) stem extract has a toxic effect on killing the larvae of Culex sp. Keyword : Culex sp. Larvae; The crown of god (Phaleria macrocarpa (Scheff.) Boerl.); Toxicity