bluuebunny/crossref_metadata_2025_split huggingface dataset:
Shared decision‐making in routine breast cancer care in Germany—A cross‐sectional study
Authors: Feiten Stefan , Scholl Isabelle , Dünnebacke Jan , Schmidt Marcus , Franzen Arno , Ernst Walter , Spaderna Heike , Weide Rudolf 
Published: February 2022

AbstractObjectiveMany preference‐sensitive decisions have to be made in breast cancer care and little is known about the decision‐making processes between breast cancer patients and the different health care professionals engaged in their treatment.MethodsAll female breast cancer patients who underwent surgery in four German breast centers between 07/2016 and 12/2018 were invited to fill in a survey. The decision‐making process was evaluated using the 9‐item Shared Decision Making Questionnaire (SDM‐Q‐9) and a German measure to assess satisfaction with care (ZAPA). The higher the total score (0–100), the higher the experienced degree of participation and satisfaction, respectively. Participants were asked to separately rate consultations with their inpatient hospital doctors, outpatient gynecologists, outpatient oncologists and primary care providers. An overall mean score for the degree of participation and the satisfaction with care was calculated for each patient across all consultations assessed. Differences between the 4 treating physician groups were analyzed as well.ResultsOf 1068 approached patients, 563 with a mean age of 62 and a standard deviation (SD) of 12.2 years filled in the survey (response rate: 53%). The overall SDM‐Q‐9 score was 73.8 (SD: 20.8). Older patients stated a higher level of participation than younger, different physician groups were rated quite similarly. Overall satisfaction with care was 87.4 (SD: 15.5).ConclusionsOverall, patients reported to have experienced a high level of shared decision‐making (SDM) and were quite satisfied with their treatment. However, we do not know whether non‐responders might have had different experiences.
Alternative prey mediate intraguild predation in the open field
Authors: Snyder Gretchen B , Smith Olivia M , Chapman Eric G , Crossley Michael S , Crowder David W , Fu Zhen , Harwood James D , Jensen Andrew S , Krey Karol L , Lynch Christine A , Snyder William E 
Published: February 2022

AbstractBACKGROUNDGeneralist predators that kill and eat other natural enemies can weaken biological control. However, pest suppression can be disrupted even if actual intraguild predation is infrequent, if predators reduce their foraging to lower their risk of being killed. In turn, predator–predator interference might be frequent when few other prey are available, but less common when herbivorous and detritus‐feeding prey are plentiful. We used molecular gut‐content analysis to track consumption of the predatory bug Geocoris sp. by the larger intraguild predator Nabis sp., in organic and conventional potato (Solanum tuberosum) fields.RESULTSWe found that higher densities of both aphids and thrips, two common herbivores, correlated with higher probability of detecting intraguild predation. Perhaps, Nabis foraging for these herbivores also encountered and ate more Geocoris. Surprisingly, likelihood of intraguild predation was not strongly linked to densities of either Nabis or Geocoris, or farming system, suggesting a greater importance for prey than predator community structure. Intriguingly, we found evidence that Geocoris fed more often on the detritus‐feeding fly Scaptomyza pallida with increasing predator evenness. This would be consistent with Geocoris shifting to greater foraging on the ground, where S. pallida would be relatively abundant, in the face of greater risk of intraguild predation.CONCLUSIONOverall, our findings suggest that while herbivorous prey may heighten intraguild predation of Geocoris in the foliage, detritivores might support a shift to safer foraging on the ground. This provides further evidence that prey abundance and diversity can act to either heighten or relax predator–predator interference, depending on prey species identity and predator behavior. © 2022 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Aedes mosquitoes in the emerging threat of urban yellow fever transmission
Authors: Gabiane Gaelle , Yen Pei‐Shi , Failloux Anna‐Bella 
Published: February 2022

AbstractThis last decade has seen a resurgence of yellow fever (YF) in historical endemic regions and repeated attempts of YF introduction in YF‐free countries such as the Asia‐Pacific region and the Caribbean. Infected travellers are the main entry routes in these regions where competent mosquito vectors proliferate in appropriate environmental conditions. With the discovery of the 17D vaccine, it was thought that YF would be eradicated. Unfortunately, it was not the case and, contrary to dengue, chikungunya and Zika, factors that cotribute to YF transmission remain under investigation. Today, all the signals are red and it is very likely that YF will be the next pandemic in the YF‐free regions where millions of people are immunologically naïve. Unlike COVID‐19, YF is associated with a high case‐fatality rate and a high number of deaths are expected. This review gives an overview of global YF situation, including the non‐endemic Asia‐Pacific region and the Caribbean where Aedes aegypti is abundantly distributed, and also proposes different hypotheses on why YF outbreaks have not yet occurred despite high records of travellers importing YF into these regions and what role Aedes mosquitoes play in the emergence of urban YF.
Toward a gliding hybrid aerial underwater vehicle: Design, fabrication, and experiments
Authors: Lyu Chenxin , Lu Di , Xiong Chengke , Hu Rui , Jin Yufei , Wang Jianhu , Zeng Zheng , Lian Lian 
Published: February 2022

AbstractThe hybrid aerial underwater vehicle (HAUV) merges the best of unmanned aerial vehicle (UAV) and unmanned underwater vehicle into one platform makes it possible to operate in both the air and water. Various possible applications of HAUV have aroused much research on it. However, the underwater endurance and operation depth of current HAUVs are still limited. This hinders the application and popularization of HAUV in rugged environments. This paper presented the design, fabrication, and testing of a novel concept HAUV, Nezha III. It is featured by its piston‐driven underwater glide strategy and combination of an underwater glider and fixed‐wing vertical takeoff and landing aircraft. In‐depth design and evaluation of the amphibious wings with tradeoffs between aerodynamic and hydrodynamic performance in both fluids was conducted. The vehicle prototype was built, and field experiments, including domain transitions and underwater operations, were conducted in Qiandao Lake, China. Due to the experiment site constraints, the computational fluid dynamics technique evaluated horizontal flight performance with fixed wings. The experimental results show that the prototype can realize rotor flight and stable domain transitions. Moreover, this piston‐driven underwater glide strategy extended the HAUV's underwater endurance over 24 h and operational depth to 25.5 m. To the best of our knowledge, Nezha III possesses the most extended underwater endurance among existing HAUVs.
Efficient recovery of superhydrophobic wax surfaces on solid wood
Authors: Arminger Benjamin , Gindl-Altmutter Wolfgang , Hansmann Christian 
Published: February 2022

AbstractSuperhydrophobic surface coatings have enormous potential to protect wood from excessive water uptake. Unfortunately, such coatings often require toxic chemicals or complex fabrication methods, and their mechanical stability is very limited. As an alternative, highly water-repellent wood surfaces with mean water contact angles (WCAs) of 160° were prepared by straightforward spray-deposition of alkyl ketene dimer (AKD) wax microparticles. While water repellency was unaffected by static loading with a cast iron weight, prolonged rubbing resulted in a strong reduction in WCA to 125° since the spherical wax microstructure was largely destroyed by the acting shear forces. Thermal treatment of such a degraded surface at 80 °C led to an almost full recovery (WCA 155°) of water repellency. Microscopy and thermal analysis revealed that exposure to temperatures above the melting range and subsequent slow cooling enable self-assembly of AKD into leaf-shaped microstructures, which are responsible for the high WCA observed. It is proposed that the thermally induced self-recovery ability will greatly enhance the utility and service life of AKD-based superhydrophobic wood surfaces and make them suitable for multiple practical applications.
Gastric Pneumatosis with Portal Venous Gas can be Treated Non‐operatively: A Retrospective Multi‐institutional Study
Authors: Epin Antoine , Passot Guillaume , Christou Niki , Monneuse Olivier , Mabrut Jean‐Yves , Ferrero Pierre‐Alexandre , Caudron Sebastien , Pezet Denis , Magnin Benoit , Grange Rémi , Lambert Céline , Williet Nicolas , Flaris Alexandros N. , Le Roy Bertrand 
Published: February 2022

AbstractBackgroundGastric pneumatosis (GP) is a rare radiologic finding with an unpredictable prognosis. The aim of this study was to identify mortality risk factors from patients presenting with GP on computed tomography (CT), and to develop a model which would allow us to predict which patients would benefit most from operative management.MethodsBetween 2010 and 2020, all CT‐scan reports in four tertiary centers were searched for the following terms: “gastric pneumatosis,” “intramural gastric air” or “emphysematous gastritis.” The retrieved CT scans were reviewed by a senior surgeon and a senior radiologist. Relevant clinical and laboratory data for these patients were extracted from the institutions’ medical records.ResultsAmong 58 patients with GP, portal venous gas and bowel ischemia were present on CT scan in 52 (90%) and 17 patients (29%), respectively. The 30‐day mortality rate was 31%. Univariate analysis identified the following variables as predictive of mortality at the time of the diagnosis of GP: abdominal guarding, hemodynamic instability, arterial lactate level >2 mmol/l, and the absence of gastric dilatation. Multivariable analysis identified the following variables as independent predictors of mortality: arterial lactate level (OR: 1.39, 95% CI: 1.07–1.79) and the absence of gastric dilatation (OR: 0.07, 95% CI: 0.01–0.79). None of the patients presenting with a baseline lactate rate<2 mmol/l died within 30 days following diagnosis, and no more than 17 patients out of 58 had bowel ischemia (29%).ConclusionsGP could be managed non‐operatively, even in the presence of portal venous gas. However, patients with arterial lactate level>2 mmol/l, or the absence of gastric dilation should be surgically explored due to a non‐negligible risk of mortality.
Spatial–temporal modeling of root zone soil moisture dynamics in a vineyard using machine learning and remote sensing
Authors: Kisekka Isaya , Peddinti Srinivasa Rao , Kustas William P. , McElrone Andrew J. , Bambach-Ortiz Nicolas , McKee Lynn , Bastiaanssen Wim 
Published: February 2022

AbstractHigh-resolution spatial–temporal root zone soil moisture (RZSM) information collected at different scales is useful for a variety of agricultural, hydrologic, and climate applications. RZSM can be estimated using remote sensing, empirical equations, or process-based simulation models. Machine learning (ML) approaches for evaluating RZSM across numerous spatial–temporal scales are less generalizable than process-based models. However, data-driven ML approaches offer a unique opportunity to develop complex models of soil moisture without making assumptions about the processes governing soil water dynamics in a given study region. In this study, comparisons were made between two models, pySEBAL and EFSOIL, which were based on evaporation fraction (EF) and soil properties, and a data-driven model based on the Random Forest (RF) ensemble algorithm. These approaches were evaluated to demonstrate their capabilities for RZSM estimation. The EF obtained from Landsat images was used after validation with eddy covariance measurements as the major input to all three models, along with other meteorological and soil physical properties. The RF model was trained using in situ soil moisture data from Time Domain Reflectometry (TDR) sensors installed in a vineyard from 2018 to 2020. The predictor variables comprised of meteorological, soil properties, EF, and a vegetation index. The results reveal that there was a strong correlation between the in situ measured soil moisture and the RF predicted soil moisture at all sensor locations. Due to the complexity of the physical processes involved in soil water flow, the empirical models pySEBAL and EFSOIL were unable to reliably predict RZSM values at all monitored locations. The high RZSM predicted by pySEBAL demonstrated the presence of possible bias in the model’s algorithm used to estimate soil moisture. We also demonstrated that ML based on the RF algorithm may be used to predict spatially distributed RZSM when a few soil moisture ground measurements are combined with remote sensing to produce soil moisture maps.
Laparoscopic management of infantile hydrocele in pediatric age group
Authors: Elhaddad Ahmed , Awad Mohamed , Shehata Sherif M. , Shehata Mohamed A. 
Published: February 2022

Abstract
Purpose
To evaluate laparoscopic management of hydroceles in pediatrics, with evaluation of the internal inguinal ring (IIR) and the PPV (patent processus vaginalis) in different types of hydroceles, and the incidence of the contralateral PPV.

Methods
The IIR and the type of hydrocele on the same side of 93 patients with 106 infantile hydroceles were evaluated and managed, in addition to contralateral side.

Results
The IIR on same side was closed in 8.5% (Type I) and patent in 91.5% (Type II and III) with different shapes. Contralateral IIR was open in 88.7% of cases. The operative time was 30.99 ± 7.23 min, with no intra-operative complication. The vas deferens and testicular vessels were secured and there were no injuries or bleeding. The conversion rate was zero, and all procedures (Type II and II) were completed totally laparoscopic. No post-operative complications except a case of tense hydrocele developed scrotal edema that managed conservatively.

Conclusion
Laparoscopic hydrocelectomy is safe, applicable and feasible for management of different types of hydroceles in pediatrics. The IIR is patent in nearly all cases with/out communication to the hydrocele. The contralateral IIR can be managed in the same session. Laparoscopic hydrocelectomy with/out hydrocelectomy and IIR closure is essential in preventing recurrence.
A new protocol for investigating visual two-choice discrimination learning in lizards
Authors: Szabo Birgit , Whiting Martin J. 
Published: February 2022

AbstractOne of the most widely studied abilities in lizards is discrimination learning. The protocols used to test lizards are often novel or adapted from other taxa without proper validation. We need to ensure that tests of discrimination learning are appropriate and properly applied in lizards so that robust inferences can be made about cognitive ability. Here, we present a new protocol for testing lizard discrimination learning that incorporates a target training procedure, uses many daily trials for efficiency and reinforcement, and has a robust, validated, learning criterion. We trained lizards to touch a cue card using operant conditioning and tested lizards separately on a colour, and pattern discrimination test. Lizards successfully learnt to touch a cue card and to discriminate between light and dark blue but had issues discriminating the patterns. After modifying the test procedure, some lizards reached criterion, revealing possible issues with stimulus processing and interference of generalisation. Here, we describe a protocol for operant conditioning and two-choice discrimination learning in lizards with a robust learning criterion that can help researcher better design future studies on discrimination learning in lizards.
A boundary element approach for the evaluation of SSI effects in presence of pile foundations under steady-state conditions
Authors: Cairo Roberto 
Published: February 2022

AbstractSimplified procedures, capable of predicting the main effects of soil-structure interaction (SSI), involving minimum computational effort are desired in engineering practice. Besides, user-friendly approaches can be incorporated into guidelines or practical recommended procedures. Nevertheless, approximate solutions need to be carefully validated through rigorous analytical or numerical methods, as well as by the comparison with experimental results or field measurements. In the case of piles, the flexibility of the soil-foundation system plays a fundamental role in structural design and the evaluation of the pile group effects still represents a crucial task in practical problem. In this paper, a Boundary Element approach based on the Stiffness Matrix Method (Kausel in Fundamental solutions in elastodynamics. A compendium, Cambridge University Press, England, 2006) is employed to investigate the key features of SSI, by comparison with the actual field data collected by Stewart et al. (Empirical evaluation of inertial soil-structure interaction effects. Rep. No. PEER-98/07, Pacific Earthquake Engineering Research Center, 1998) from instrumented sites and structures.
On subset-resilient hash function families
Authors: Yuan Quan , Tibouchi Mehdi , Abe Masayuki 
Published: February 2022

AbstractIn this paper, we analyze the security of subset-resilient hash function families, which is first proposed as a requirement of a hash-based signature scheme called HORS. Let $${\mathcal {H}}$$
H
be a family of functions mapping an element to a subset of size at most k. (r, k)-subset resilience guarantees that given a random function H from $${\mathcal {H}}$$
H
, it is hard to find an $$(r+1)$$

(
r
+
1
)

-tuple $$(x,x_1,\ldots ,x_r)$$

(
x
,

x
1

,
…
,

x
r

)

such that (1) H(x) is covered by the union of $$H(x_i)$$

H
(

x
i

)

and (2) x is not equal to any $$x_i$$

x
i

. Subset resilience and its variants are related to nearly all existing stateless hash-based signature schemes, but the power of this security notion is lacking in research. We present three results on subset resilience. First, we show a generic quantum attack against subset resilience, whose time complexity is smaller than simply implementing Grover’s search. Second, we show that subset-resilient hash function families imply the existence of distributional collision-resistant hash function families. Informally, distributional collision resistance is a relaxation of collision resistance, which guarantees that it is hard to find a uniform collision for a hash function. This result implies a comparison among the power of subset resilience, collision resistance, and distributional collision resistance. Third, we prove the fully black-box separation from one-way permutations.
The Contributing Role of Family, School, and Peer Supportive Relationships in Protecting the Mental Wellbeing of Children and Adolescents
Authors: Butler Nadia , Quigg Zara , Bates Rebecca , Jones Lisa , Ashworth Emma , Gowland Steve , Jones Margaret 
Published: February 2022

AbstractGlobally, mental disorders are the leading cause of disability in children and adolescents. Previous research has demonstrated that supportive relationships are a key protective factor against poor mental health in children, particularly amongst those who have experienced adversity. However, fewer studies have examined the relative impact of different types of supportive relationships. The current study examined the association between level of family adult support, school adult support, and school peer support and mental wellbeing in a sample of children (age 8–15 years, N = 2,074) from schools in the UK. All three sources of support were independently associated with mental wellbeing. Analyses demonstrated a graded relationship between the number of sources of support and the odds of low mental wellbeing (LMWB), reflecting a cumulative protective effect. While all three sources of support were best, it was not vital, and analyses demonstrated a protective effect of school sources of support on LMWB amongst children with low family support. Peer support was found to be particularly important, with prevalence of LMWB similar amongst children who had high peer support (but low family and school adult support), and those who had high family and school adult support, (but low peer support), indicating that high peer support has an equivalent impact of two other protective factors. Findings from the study highlight the crucial context schools provide in fostering positive peer relationships and supportive teacher–student relationships to promote mental health and resilience for all children, including both those with and without supportive home environments.
Ubiquitin carboxyl-terminal hydrolase 11 promotes autophagy by de-ubiquitinating and stabilizing Beclin-1
Authors: Li Zheng , Rao Shaohong , Song Chunwei , Zhu Min , Zhao Hongchang , Yuan Shuping , Peng Bin , Xu Xingzhi 
Published: February 2022

AbstractAutophagy is a major degradation process that degrades and recycles cytoplasmic materials through lysosome for maintaining cellular homeostasis. Dysregulated autophagy is linked with numerous human diseases including cancer. Autophagy marker protein B-cell lymphoma-2 interacting protein 1 (Beclin-1) is essential for autophagosome initiation and maturation. Recently, Ubiquitin carboxyl-terminal hydrolase 11 (USP11) has been reported to promote or inhibit autophagy without identification of any direct target. Here through biochemical reaction in vitro, we demonstrate that USP11 directly interacts with Beclin-1. Both in vitro and in vivo de-ubiquitination assays revealed that USP11 de-ubiquitinates Beclin-1. USP11-mediated de-ubiquitination stabilized Beclin-1 and enhanced the formation of the autophagy-specific class III phosphatidylinositol 3-kinase complexes 1 and 2, thereby promoting autophagy. Together, our results demonstrated that USP11 promotes autophagy under unperturbed conditions by de-ubiquitinating and stabilizing Beclin-1 which may serve as a therapeutic target for autophagy-related diseases.
Evaluation of the function of a luciferase-like monooxygenase homologue in 4,4´-dithiodibutyric acid catabolism in Rhodococcus erythropolis MI2
Authors: Venkateswar Reddy M. , Steinbüchel Alexander 
Published: February 2022

AbstractThe bacterium Rhodococcus erythropolis MI2 uses 4,4´-dithiodibutyric acid (DTDB) as carbon source to synthesize polythioesters (PTE). The first step for the production of PTE using DTDB is catalyzed by an NADH:flavin oxidoreductase (nox) as it was previously shown in our laboratory, and the second step is catabolized by a putative luciferase-like monooxygenase (Llm). In the current study, experiments were carried out to identify the function of Llm. Hence, the llm gene, which encodes for the Llm protein, was amplified from the genomic DNA of MI2 using polymerase chain reaction and expressed in Escherichia coli BL21 cells. Protein purification was done using His Spin Trap affinity columns. Enzyme assay was carried out using the purified protein and p-coumaric acid as substrate giving a specific activity of 1.6 U/mg protein for the purified Llm. The responsible gene (llm) was deleted in the genome of MI2, and a single deletion mutant was subsequently generated. Finally, growth of the wild-type strain (MI2) and the mutant strain (MI2Δllm) were compared using DTDB or succinate as carbon sources. Whereas the wild type was successfully grown with DTDB or succinate, the llm-negative mutant exhibited low grow with DTDB although it grows very well with succinate.