bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phytochemical and medicinal properties on Strychnos-nux-vomica (L)
Authors: Perumal B  , Velmani S  , Santhosh C  , Maruthupandian A  
Published: June 2022

Strychnos nux-vomica L. (Loganiaceae) is a deciduous tree that grows in tropical areas and is distributed throughout India and Southeast Asia. The dried seed of this plant S. nux vomica has been applied clinically in Chinese medicine for hundreds of years. S. nuxvomica is a non edible tree with a strong content of two poisonous alkaloids, strychnine and brucine. S. nux-vomica which belongs to the family loganiaceaalso called Kanjiram is a medium-sized tree. Other names of S. nux-vomica are Kanjiram, Kuchla, Kupilu. Phytochemical analysis revealed the presence of alkaloid, carbohydrate, tannin, steroid, triterpenoid and glycoside in the extract. Seeds of Nux vomica used as nervine tonic, alexiteric, aphrodisiac, anthelmintic, digestive, purgative and stimulant. Detoxified S. Nux vomica seeds used in various Ayurvedic drugs like Agnitundi vati, Navjeevan Rasa and vishatinduka vati as an important ingredient. This study presents a review on the Phytochemical and Medicinal properties of S.nux vomica L.
Impact of ethyl methane sulphonate on M1 attributes of Groundnut with special emphasis of amino acid profiling
Authors: Muniappan V  , Palanivel S  , Parvathi S  
Published: June 2022

The present investigation was undertaken to know the effect of EMS on groundnut cultivar TMV-7 particularly for M1 generation with special reference to amino acids. The healthy and viable seeds of groundnut cultivar TMV-7 were exposed to different concentrations of EMS. The chemical mutagens were screened against groundnut ranged from 10 to 50mM and sown in the field along with control. The various growth, morphological parameters like percentage of seed germination, survival percentage plant height, number of branches, days taken for flower initiation , total height at time of harvest, root length, number of lateral roots, number of pods per plant and 100 seeds weight were decreased with increasing concentrations of EMS. The amino acid analysis also carried out in control, EMS derived M1 plants grown in field. The amino acid contents were recorded in both positive and negative tendency.
Molecular docking studies of bisazo derivatives of 4-Acetyl resorcinol against lung cancer protein EGFR
Authors: Siddiqua .S  , Sithick Ali K  
Published: June 2022

Lung cancer is one of the malignant diseases mostly caused by tobacco users. EGFR, proto oncogene plays an important role in many biological processes apoptosis, transcriptional regulation, cell differentiation, cell spreading and mobility. The mutation occurs in EGFR, the normal function of EGFR is over expressed and leads to develop lung cancer. In this present study, we have developed lung cancer drug from bisazo derivatives through molecular docking studies against EGFR using Glide. From the docking results the compound I, IV and V have a better life score when compared to other compounds. The ADME properties were carried out for five bis azo molecules. These compounds are under acceptable range with predicted ADME properties. From the In-silico docking studies, we conclude the compounds I, IV and V are good drug for lung cancer and inhibit over expression of EGFR in human.
Ovicidal response effects of selected plant essential oils against Aedes aegypti
Authors: Rajasekar P  , Jebanesan A  , Mohamed Shamsudin  , Antony Joseph Jerold I  , Meeramaideen M  , Salahudeen M  , Thirupathi R  
Published: June 2022

The ovicidal response of selected plant essential oils was evaluated under laboratory conditions against Aedes aegypti. Three plant oils viz., Abutilon indicum, Acacia nilotica and Acalypha indica were tested for ovicidal response assays at six different concentrations viz., 75, 125, 175, 225, 275 and 325 ppm concentrations. The ovicidal activity degreasing of essential oils against Aedes aegypti were Acacia nilotica > Acalypha indica and Abutilon indicum.
Structural delving and insilico analysis of proteins of Rhinacanthus Nasutus- an indigenous medicinal plant
Authors: Rubalakshmi G  , Nirubama K  , Prabhakaran S  
Published: June 2022

Medicinal plants are staging a comeback and ‘renaissance’ is happening all over the globe. The Medicinal plants products today symbolise safety in contrast to the synthetics that are regarded as unsafe to human and environment. So the medicinal plants have a promising role in to prevent and as well as to cure the diseases. Andrographis is an important genus of the family Acanthacae known for its ethanomedicinal claims and for a variety of medicinal properties. Rhinacanthus nasutus has been used in various folk medicinal preparations and its chemical composition and pharmacological activities have been elaborated recently. Functional characterization of a protein sequence is one of the most frequent problems in biology. This task is usually facilitated by accurate three-dimensional (3-D) structure of the protein. The number of protein sequences that can be modeled, as well as the accuracy of the prediction, is increasing steadily because of the growth and number of known protein sequences and structures as well as improvements in the modeling software. It is currently possible to model, with useful accuracy. Significant parts of approximately one half of all known protein sequences. This research report render a futuristic summary of bioinformatics study of Rhinacanthus nasutus with emphasis on the current development and future directions, which shall provide tools and resources necessary to understand and uphold advances in this important field. The aim of the present study, 2 proteins of Rhinacanthus nasutus were analysed using bioinformatics tools. Structural prediction and functional characterization of proteins of Rhinacanthus nasutus were done using Expasy Protparm server, 3D structure was done using SWISS MODEL. Plants of different family showing identity 80% and above were selected and its sequences retrieved, aligned using Clustal Omega. phylogenetic tree was constructed for the aligned sequence. Structure prediction showed that α – helix, random coil, β – turn and extended strand predominates. Phylogenetic analysis of rbcl of Rhinacanthus nasutus reveals that the Plants of Verbenaceae, Bignonaceae, and Fabaceae family are closely related. Hence the present article includes the detailed exploration of Computational tools of protein, and bioinformatic aspects of R.nasutus in an attempt to provide a direction for further research.
Kinetics and Mechanism of Oxidation of Tartaric Acid by N-Chloronicotinamide (NCN)
Authors: Pushpalatha L  , Baskaran P.R  , Saratha K  
Published: June 2022

The oxidation of tartaric acid by N-chloronicotinamide in the presence of H2SO4 is studied. First order kinetics with respect to NCN is observed. The kinetics results indicate fractional order dependence about [tartaric acid]. Inverse first order in [nicotinamide] and inverse fractional order about [H+] are noted. Rate of the reaction increases with a decrease in the percentage of acetic acid. The values of rate constants observed at four different temperatures were utilized to calculate the activation parameters. A suitable mechanism consistent with the experimental findings has been proposed.
Kinetics and Mechanism of oxidation of Maltose By N-Bromonicotin amide (NBN)
Authors: Pushpalatha L  , Baskaran P.R  , Saratha K  
Published: June 2022

Kinetics study of oxidation of maltose, by aqueous alkaline solution of N-Bromonicotinamide (NBN) has been carried out in the temperature range 308-323K.The reaction exhibits first order in [KOH] and [Maltose] and zero order about oxidant. Addition of nicotinamide (NA) has no effect. Increase in ionic strength of the medium does not change the rate. Effect of temperature on the rate of oxidation has been followed to show the validity of Arrehenius equation and various activation parameters have been computed. The stoichiometry of the reaction was found to be 1:1. 1,2-enediol is found to be the reactive intermediate. Maltobionic acid is the product of oxidation.
Optimization and characterization of green synthesized silver nanoparticles and its inhibitory activity against biofilm forming bacterial pathogens
Authors: Maniraj A  , Muthuram Kumar S  , Kannan M  , Rajarathinam K  , Pushparaj A  
Published: June 2022

In the present study, antibacterial activity of silver nanoparticles synthesized from entophytic fungi extracts were analysed against biofilm forming bacteria include the Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Pseudomonas aeruginosa isolated from clinical specimens. Therefore, we tried to establish a combination of medicinal and nanotechnology possibly with the field of medicine for the development of antibacterial agents against these strains. The nanoparticles were characterized by UV–visible spectroscopy, the presented and capped molecules of proteins with nanoparticles was confirmed by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD).
UV–visible studies display an absorption band at 420 nm due to surface Plasmon resonance (SPR) of the silver nanoparticles. The intra cellular synthesized silver nanoparticles (Ag NPs) size 15-35 nm was determination of X-ray diffraction (XRD) crystal calculation, antimicrobial activity higher than the standard antibiotic. The nanoparticle treated with isolated bacteria as result macromolecule of proteins denatures and oozing out the cells and measure the Bradford method. The nanoparticle treated bacterial cells were compared to negative control more amount of protein released. The nano size establishing the silver nanoparticles directly bind with DNA of the pathogenic bacterial strains most important to higher antimicrobial activity.
Synthesis of Mg2+ doped NiO nanoparticles and their structural and optical properties by Co-precipitation method
Authors: M. Karthi keyan  , P. Vijaya Kumar  , A. Jafar Ahamed  , Ravikumar A  
Published: June 2022

Nanocrystalline Magnesium-doped NiO nanoparticles (Mg2+ doped NiO NPs) were synthesized by co-precipitation method. The prepared samples were characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), ultraviolet- visible spectrometer (UV-Vis) and Tunneling electron microscopy (TEM) with EDAX specifications. XRD pattern reveals that Mg2+ doped NiO nanoparticles belongs to the face centered cubic crystal structure with the space group of Fm-3m. Electron microscopy studies clearly evidence the formation of cubical edged nanoparticles with an average particle size of 21.49 nm, emerges in the polycrystalline nature. UV-Visible absorption spectra of Mg2+ doped NiO nanocrystals shows an absorption peak at 289nm. The bandgap value is calculated to be 4.8 eV.
Enhanced solar light active CoTiO3 coupled Sr, N codoped TiO2 heterojunction composites: fabrication, photocatalytic properties analysis and dye degradation studies
Authors: Murugesan Sivakumar  , Santhanam Sivakumar  , Menakshisundaram Ravikrishnan  , Ethiraj Krishnan  
Published: June 2022

The photocatalytic degradation efficiency of CoTiO3 coupled Sr, N codoped TiO2 has been examined by the degradation of Reactive Yellow 84 (RY 84) under solar light irradiation. The efficient CoTiO3/Sr, N codoped TiO2 based heterojunction composite was prepared via dispersed method and the results were compared with Sr, N codoped TiO2 and bare TiO2. The prepared photocatalysts were analyzed by x-ray diffraction [XRD], scanning electron microscopy [SEM] and diffused reflectance spectroscopy [UV-DRS] and Photoluminescence study [PL] , which implies the crystal structure, surface morphology, optical properties and quenching of electron role recombination. The charge separation of CoTiO3/Sr, N codoped TiO2 heterojunction composite has been improved as a result of coupling CoTiO3 and Sr, N codoped TiO2 with different energy levels and the responsible for the enhancement in the rate of photocatalytic degradation. The CoTiO3/Sr, N codoped TiO2 heterojunction composite shows better photostability at continuous photocatalytic runs. Our report will helps in the establishment and development of photocatalytic research.
Protective effect of Toddalia asatica leaf extract on Mild steel in 1.0N HCl
Authors: Sangeetha Thangaraja  , Mathusudhan M  , Deepa Rani P  , Selvaraj S  
Published: June 2022

A study has been made on the Novel corrosion inhibitor on mild steel in 1.0N HCl. Commonly deterioration of steel is caused due to various environmental and other chemical factors. It is unavoidable but protectable using inhibition methods. Here the usual inhibitor is replaced by green inhibitors to evade toxicity, easy availability, and to minimize the waste. This work seeks out to analyze the dried leaves of Todalia Asiatica as an inhibitor on mild steel in 1.0N HCl. The anticorrosive effectiveness of this inhibitor is studied by using non- electrochemical and electrochemical techniques. Non -electrochemical studies such as the effect of time (87.6%) and temperature (93.0%) at optimum concentration show the maximum inhibition efficiency of the inhibitor due to the formation of an inhibited layer by the inhibitor on the metal surface. Langmuir isotherm most closely fits into the info data obtained suggesting the physical adsorption between the extract and the mild steel substrate. Electrochemical such as potentiodynamic polarization studies proved that extract of Todalia Asiatica dried leaves is a cathodic type of inhibitor and 85.12% inhibition efficiency provided by the inhibitor. Charge Transfer Resistance (Rct) value increased and also Double-layer capacitance (Cdl) value decreases by EIS studies. The observed inhibitor efficiency at optimum inhibitor concentration is 84.05%. Surface and corrosion product Analysis (EDX/FTIR) was carried out to determine the corrosion-inhibitive properties of the samples.
A study on natural dyeing of cotton using Cocos Nucifera
Authors: Bavadharani S  , Sunitha R  
Published: June 2022

Natural dyes are obtained from roots, leaves, barks, fruits and fruit-coat or wood of the plants. It exhibits better bio-degradability and has a better suitability with the environment and its use in coloration of fabric materials is the consequences of increased environmental awareness. The aim of this research work is to extract dye from natural source and perform an experimental analysis of the dye adherence on cotton fabric. The natural source selected for the study is the nonedible portion of cocos nucifera at fresh and dried stages. The dye extraction was carried out using water and methanol. Then the cotton fabric was dyed and analysed for various physical and colour fastness properties. The aqueous extract of green coconut shell on the cotton fabric had good dye adherence and colour fastness. It was observed that the dyed fabrics exhibited good strength and colourfastness properties.
Nutrient content of fresh and nutrient retention in cooked Solanum nigrum Linn. leaves and green berries
Authors: Samja Sabu  , Kalpana C. A  
Published: June 2022

At present, the demand for nutraceuticals in lifestyle diseases is increasing due to its low side effects. Many of the vegetables which we include in the diet itself possess nutraceutical properties besides its culinary purposes. Many such plants are still unfamiliar to the common man due to lack of awareness about their therapeutic potentials. Solanum nigrum Linn. is a plant which belongs to the family Solanacea and possess nutraceutical properties. Nutrient retention of vegetables subjected to different cooking methods varies. The present study aimed to analyse the nutrient content and estimate the percentage of nutrient retention in Solanum nigrum Linn. leaves and green berries subjected to different cooking methods. Fresh leaves and green berries were harvested from the green house in which cultivation was done and were cooked by boiling, pressure cooking, steaming, sautéing and microwave. Nutrients in both fresh and cooked leaves and berries were analyzed using standard procedures using Millipore water. The percentage of nutrient retention in each cooked sample was calculated using USDA true retention formula. Findings revealed that among the cooked leaves, the steamed leaves possessed more carbohydrates and proteins while in case of green berries, more crude fibre and carbohydrates was seen. Besides these, a significant amount of iron, calcium, phosphorus and vitamin C contents were present in steamed leaves and green berries when compared with other cooking methods. Similar results were observed in case of percentage of nutrient retention also. From the results, it can be concluded that, steaming is the best method of cooking to retain more nutrients in Solanum nigrum Linn. leaves and green berries. Since the fresh leaves and green berries is normally not consumed by humans, steaming may be considered as the best method for human consumption to avail the maximum nutritional and therapeutic benefits of the leaves and green berries.
Citrus sinensis peel for eco friendly fragrance on textiles
Authors: Aneetta VJ  , Amsamani S  
Published: June 2022

Food production and processing generates huge amount of waste and by-products, causing irreversible environmental damage. Most of these waste/ by-products are untreated and underutilized, it is either burnt, dumped/ end up in landfills. Safe utilization of these will prevent disease transmission and pollution. So it is important to find ways to treat this waste and give a second life. Food industries waste can be used as raw material in textile industry to produce value added products. Costumer’s need for special finish on textiles has generated many opportunities for innovative finishes. But these competitions for better sales and profit have led to environmental degradation. Hence finishing using sustainable means is the need of the hour and the investigator selected Citrus sinensis peel an organic waste for the study. Being an unavoidable part in textile treatments, finishes should be highly efficient, durable, and cost effective and manufactured in an environmentally sustainable manner. In this study Nanotechnology, Ultrasonic and Microencapsulation method has been carried out. From subjective evaluation conducted it is clear that nano particle coated fabric have better fragrance than microencapsules padded fabric. The role of Citrus sinensis peel as a natural fragrance finishing agent can be confirmed through this study. Hence this study can be taken as a basis for taking up many more natural materials for fragrance finishing and applied in other textile products.
Development and evaluation of indigenous snack Promega Khakra enriched with omega-3 rich canola oil and flax seed
Authors: Akshata A Kamatha  , Navaneetha Ramachandra  , Usha Devi C  
Published: June 2022

There has been an increase in the incidence of life style diseases like, obesity, diabetes mellitus, high blood pressure etc., in our society. Awareness regarding the role of food in causing these lifestyle diseases has also increased among the population. Print media and social media have also started highlighting the ill effects of poor food choices. In general people have become health conscious and acknowledge the importance of healthy food when compared to the easily available junk and fast food. The Corona pandemic has also increased the demand for healthy nutrition. Therefore, there is a need to develop products which will meet the demands of this ever-growing health conscious population. These newer products should be preservative free, natural and should also have health benefits. High levels of Low-density lipoprotein (LDL) cholesterol in an individual has been associated with a wide range of cardiovascular diseases. Omega-3 fatty acids play a significant role in lowering high LDL cholesterol levels. Omega-3 fatty acids also improve cognitive functions among all age groups. There are very few vegetarian foods which provide omega-3 fatty acids. Khakra is a popular traditional Gujarati snack prepared mainly from wheat flour. An attempt has been made to develop a healthy khakra enriched with protein and omega-3 fatty acids (Promega khakra). Various flours like, wheat flour, gram flour, jowar flour and seeds like flax seeds and chia seeds were used in the development of this healthy enriched khakra. Canola oil was used in the preparation of the enriched khakra. Different compositions and combinations were tried to arrive at an acceptable product. These variations were evaluated for their acceptability using a 9 point hedonic scale by 25 semi trained panelists. Sensory evaluation and statistical analysis revealed that khakras (V-1) made with the following ingredients wheat flour (32%), ground flax seeds (19%), jowar flour (6%), gram flour (6%), canola oil (23%), kasuri methi (5%), cumin seeds (3%), turmeric powder (2%), red chilli powder (2%) and salt (2%) was well accepted (7.64 ± 0.71) . Nutritional composition of the standardised khakra showed the following per 100gms: Energy 410.88 kcals, carbohydrates 49.66 g, protein 12.24 g, fat 22.85g, total fiber 9.38g, moisture 1.56 per cent, ash 4.31 percent. The omega-3 content was 2.6 per 100gm (2 promega khakras) which meets approximately 3/4th of the daily requirement of an adult. The healthy Promega khakras thus developed can be consumed by all age groups.
Nutrients and nutraceutical content of polished and unpolished kodo millet – a quantitative analysis
Authors: Rajeswari N  , Dr V. Premala Priyadharshini  
Published: June 2022

Kodo millet (Paspalum scrobiculatum) is an ethnic underutilized millet variety of south India with bounty of health benefits due to the abundance of dietary fiber antioxidant and minerals like iron. This gluten free wonder millet can be a healthy alternate dietary source for diabetic, obesity and CVD patients. Scientific evidence based studies on nutritional quality of this millet both in polished and unpolished form is less. The current study aims at “Analyzing the quantum of nutrients and nutraceutical present in polished and unpolished Kodo Millet”. Both polished and unpolished Kodo millets were procured from local market, cleaned to remove dirt, dust and stone. The cleaned millets were dried powdered and sieved using 60 mesh sieves (250 Micron) . The powdered millet flour was stored in airtight container. Nutritional content of Kodo millet was analysed for macro, micro nutrients and nutraceutical content of both polished and unpolished form using standard AOAC method - 20th edition (2016). The analysed nutrient content were compared statistically at 99% and 95 % confidence interval (t-test). The result shows that, the quantum of carbohydrate present in polished kodo millet was 10.53 % lesser than the milled parboiled rice and 8.1 % lesser than the brown rice and 11.61 % lesser than the raw milled rice. The total dietary fibre content of unpolished kodo millet was 12.98 gm, this value was almost double the amount of total dietary fibre present in samai (7.72 gm). Crude fibre content of unpolished kodo millet was noted as 7.66 gm – which is more than seven times the crude fibre content of raw and parboiled rice (0.2 gm) and more than six times the crude fibre content of whole wheat (1.2gm) respectively as per Nutritive value of Indian food.