bluuebunny/crossref_metadata_2025_split huggingface dataset:
Progress in research of sulfobetaine surfactants used in tertiary oil recovery
Authors: Lu Jiayue , Pu Wanfen , He Wei , Zou Binyang , Li Bowen , Liu Rui 
Published: December 2022

AbstractThe synthesis of sulfobetaine surfactants and their application in tertiary oil recovery (TOR) are summarized in this paper. The synthesis of sulfobetaine surfactants was classified into three categories of single hydrophobic chain sulfobetaine surfactants, double hydrophobic chain sulfobetaine surfactants and Gemini sulfobetaine surfactants for review. Their application in TOR was classified into surfactant flooding, microemulsion flooding, surfactant/polymer (SP) flooding and foam flooding for review. The sulfonated betaine surfactants have good temperature resistance and salt tolerance, low critical micelle concentration (cmc) and surface tension corresponding to critical micelle concentration (γcmc), good foaming properties and wettability, low absorption, ultralow interfacial tension of oil/water, and excellent compatibility with other surfactants and polymers. Sulfobetaine surfactants with ethoxyl structures, hydroxyl and unsaturated bonds, and Gemini sulfobetaine surfactants will become an important direction for tertiary oil recovery because they have better interfacial activity in high‐temperature (≥90°C) and high‐salinity (≥104 mg/L) reservoirs. Some problems existing in the synthesis and practical application were also reviewed.
Fermented Cerasus humilis fruits protect against high‐fat diet induced hyperlipidemia which is associated with alteration of gut microbiota
Authors: Wang Yu , Han Chao , Cheng Jinghe , Wang Zhanjun , Liu Lulu , Huang Houyu , Liang Qiuxia , Liu Ruiying , Ran Beibei , Li Weidong 
Published: December 2022

AbstractBACKGROUNDHyperlipidemia is regarded as a public health matter, and its effective prevention and treatment are urgently required. However, the treatment of hyperlipidemia is still relatively scarce.RESULTSFermented Cerasus humilis fruit (FCHF) had higher total flavonoid, total phenolic, procyanidin, and organic and free amino acid content, and lower total sugar content, than non‐fermented C. humilis fruit (NFCHF). Both FCHF and NFCHF treatment significantly prevent putting on weight. Furthermore, FCHF administration ameliorated hyperlipidemia and cholesterol over‐accumulation. In addition, FCHF administration activated the antioxidase system and decreased the malondialdehyde content to relieve oxidative stress, and showed more efficaciously than NFCHF administration. FCHF treatments significantly reverse the fat deposition in high‐fat diet rat liver. FCHF supplementation can relieve the dysbacteriosis induced by hyperlipidemia, and regulate the composition of rat gut microbiota by increasing the abundance of Prevotella and norank_f_Muribaculaceae.CONCLUSIONLactobacillus plantarum and Saccharomyces cerevisiae fermentation enhanced the antihyperlipidemic property of C. humilis fruits by promoting gut microbiota regulation. © 2022 Society of Chemical Industry.
Goat milk powder supplemented with branched‐chain fatty acid: influence on quality and microstructure
Authors: Fan Xiaoxue , Yuan Xinlu , Huang Mengyao , Wang Cunfang , Jiang Hua , Zhang Xiaoning , Sun Hongyan 
Published: December 2022

AbstractBACKGROUNDBranched‐chain fatty acid (BCFA) is effective in preventing and helping to treat neonatal necrotizing enterocolitis. It is essential to supplement goat‐milk powder for formula‐fed preterm infants with BCFA. In this study, the quality and microstructures of milk powders supplemented with different concentrations of BCFA were evaluated, using goat milk powder without BCFA as the control group (CG).RESULTSIn comparison with the CG, goat milk powder supplemented with BCFA exhibited smaller fat globules and a significant drop in overall particle size. During 16 weeks of storage, BCFA‐supplemented groups showed suitable moisture content and viscosity and good solubility. The BCFA also helped reduce the number of folds on the surface of the milk powder particles.CONCLUSIONThe findings of this study indicate that goat milk powders with BCFA exhibit differences in quality and microstructure in comparison with ordinary goat milk powder, which is relevant for the future development and application of BCFA in foods. © 2022 Society of Chemical Industry.
Multi‐criteria decision analysis integrated with GIS to determine land suitability for cultivation and best harvest time of vine
Authors: Amin Hosein , Mokarram Marzieh , Zarei Abdol Rassoul 
Published: December 2022

AbstractBACKGROUNDIn this study, the quality of land suitability for vine cultivation in south‐western Iran was evaluated and a land suitability map for vine cultivation was developed using the fuzzy‐analytic hierarchy process (AHP). The best harvest time of vines was determined based on the relationship between total soluble solids (TSS) and titratable acidity (TA) with fruit colour (red, green, and blue or RGB) in ten points and also the growing degree‐days (GDD) maps from April to December. The relationship between GDD and effective parameters in vine cultivation was determined using principal component analysis (PCA) and Pearson correlation methods.RESULTSThe results illustrated that the maximum temperature and relative humidity (RH) have the greatest effect on vine cultivation and its yield (weight 0.24). The results of the land suitability map showed that central regions have better conditions for growing vines (32%). The measurements of TA and TSS depicted that vines of the northern parts have higher TA and lower TSS and there is a significant relationship between them and fruit colour. The results of GDD maps showed that the harvest time of ruby vine and Gezel‐azm is July and August, respectively. Also, the temperature (Tmean, Tmax and Tmin), wind speed, and GDD were the most important parameters to determine the best location for vine cultivation.CONCLUSIONDetermining land suitability for cultivation, the best harvest time, the time of grape ripening, and following the exact time of export and import of vine has a vital role to increase its productivity and services. © 2022 Society of Chemical Industry.
Broccoli seed extract rich in polysaccharides and glucoraphanin ameliorates DSS‐induced colitis via intestinal barrier protection and gut microbiota modulation in mice
Authors: Wu Jiaying , Guo Weiling , Cui Shumao , Tang Xin , Zhang Qiuxiang , Lu Wenwei , Jin Yan , Zhao Jianxin , Mao Bingyong , Chen Wei 
Published: December 2022

AbstractBACKGROUNDBroccoli has received widespread attention because of its anti‐inflammatory and antioxidant effects. The present study aimed to explore the composition of broccoli seed extract (BSE) and its effect on colitis induced by dextran sulfate sodium (DSS).RESULTSBSE mainly comprises glucoraphanin and polysaccharides composed of arabinose, galactose, glucose and mannose. Animal experiments suggested that BSE intervention effectively reversed body weight loss, suppressed the levels of proinflammatory interleukin‐6, tumor necrosis factor‐α and interleukin‐1β, and elevated the levels of anti‐inflammatory interleukin‐10 and the activities of superoxide dismutase and glutathione in DSS‐induced colitis mice. According to histopathologic and immunohistochemical analysis of colon tissue, BSE intervention may repair the intestinal barrier by upregulating mRNA levels and the expression of tight junction proteins (claudin‐1, occludin and zonula occludens‐1). Gas chromatography–mass spectrometry (MS) analysis demonstrated that cecal short‐chain fatty acids in mice with BSE administration were significantly increased compared with the model group. Sulforaphane and sulforaphane‐N‐acetylcysteine were only detected in BSE group mice by ultra‐performance liquid chromatography‐MS analysis. In addition, BSE intervention evidently increased the abundance of Alistipeds, Coriobacteriaceae UCG‐002 and Bifidobacterium and decreased the abundance of Escheichia‐Shinella, Lachnospiraceae others, Parabacteroides, Ruminococcaceae others and Turicibacter, which possibly promoted carbohydrate metabolism and short‐chain fatty acid production.CONCLUSIONThe present study aimed to elucidate the effect of BSE on colitis and found that BSE, as a novel food ingredient, has great potential for the improvement of colitis. © 2022 Society of Chemical Industry.
Identifying European and Chinese styles of creating tourist destinations with intangible cultural heritage: A comparative perspective
Authors: Qiu Qihang , Liang Xiaomei , Zuo Yifan 
Published: December 2022

AbstractTo identify the process of tourism place making by using intangible cultural heritage (ICH) as the resource, this study conducts a qualitative meta‐analysis based on 23 European and 16 Chinese cases. The results conclude and replenish the main considerations in creating tourist destinations with ICH, including planner, ICH type, specific place making scope, purpose, design focus, types of placemaking, and sense of place. Findings reveal differentiated patterns and similar methods in the decision‐making process in the two regions. This article provides a new perspective on taking ICH as place making tool and sheds light on ICH resource development.
CircNFIX stimulates the proliferation, invasion, and stemness properties of ovarian cancer cells by enhancing SH3RF3 mRNA stability via binding LIN28B
Authors: Yu Xiu‐Zhang , Yang Bo‐Wen , Ao Meng‐Yin , Wu Yu‐Ke , Ye Hui , Wang Rui‐Yu , Xi Ming‐Rong , Hou Min‐Min 
Published: December 2022

AbstractWe aimed to study the regulatory roles and mechanism of circular nuclear factor IX (circNFIX) in cancer growth and stemness properties of ovarian cancer (OC). CircNFIX and SH3RF3 levels in OC tissues and cells were tested by quantitative real‐time PCR. RNase R treatment quantified circNFIX RNA stability. Molecular interaction among circNFIX, LIN28B, and SH3RF3 was predicted by bioinformatics software and validated through RNA immunoprecipitation (RIP) assay. The gain‐ or loss‐experiments of circNFIX on capabilities of metastasis and stemness in vitro were assessed using Cell Counting Kit‐8, Transwell, western blot, and sphere‐formation assays. CircNFIX and SH3RF3 were markedly elevated in OC tissues and OC cells. Knocking down circNFIX repressed the proliferation, migration, invasion, and stemness properties of A2780 and SKOV3 cells. The RIP assay verified the direct binding relationship between LIN28B, circNFIX, and SH3RF3. Additionally, overexpression of circNFIX elevated the SH3RF3 expression, while this effect was reversed by LIN28B silence. Rescue experiments demonstrated that the overexpression of SH3RF3 reversed the knockdown of circNFIX on OC cells' proliferation, metastasis, and stemness properties. CircNFIX improved the mRNA stability and translation of SH3RF3 via recruiting LIN28B, thus promoting the proliferation, invasion, and stemness properties of OC cells in vitro.
Knowledge‐based dynamic capability: Concept mapping, usage, and taxonomy
Authors: Bindra Sunali , Sharma Deepika , Bhardwaj Rohit , Dhir Sanjay , Srivastava Saurabh 
Published: December 2022

AbstractKnowledge‐based dynamic capability (KBDC) is a firm's ability to acquire, create, and combine knowledge to identify and exploit opportunities while addressing the dynamics of environmental changes. Based on a systematic review and analysis of the extant literature related to KBDC from 1959–2020, we aim to trace significant theories, contexts, characteristics, and methodologies (TCCM) and their inter‐relationships to present a holistic view of the KBDCs research. In particular, the study attempts to address the issues inherent in organizing, designing, and executing KBDCs towards the attainment of the firm's strategic and organizational objectives. The study uses a structured methodological approach for conducting a systematic literature review to determine the existing contributions and by proposing the frameworks for future research. By conducting TCCM and bibliometric analysis of the existing KBDCs literature, the study provides comprehensive networks, significant countries, eminent authors, prominent theories, context, characteristics, and methodologies in this field. The analysis, therefore, addresses the managerial concerns over the entire spectrum of knowledge‐based entities and bridges the gaps, such as application bias in large organizations, developed nations, and single‐level analysis by exploring potential relationships regarding KBDC. Overall, the study provides the logical concept mapping, usage, and taxonomy contributing towards the strengthening of KBDC. In addition, the study also presents areas in which research has made the most progress as well as those in which gaps and unsolved tensions persist. The epistemological exploration traces the significant contributions for determining the future research scope.
Joint Vestibular Schwannoma Enlargement Prediction and Segmentation Using a Deep Multi‐task Model
Authors: Wang Kai , George‐Jones Nicholas A. , Chen Liyuan , Hunter Jacob B. , Wang Jing 
Published: December 2022

ObjectiveTo develop a deep‐learning‐based multi‐task (DMT) model for joint tumor enlargement prediction (TEP) and automatic tumor segmentation (TS) for vestibular schwannoma (VS) patients using their initial diagnostic contrast‐enhanced T1‐weighted (ceT1) magnetic resonance images (MRIs).MethodsInitial ceT1 MRIs for VS patients meeting the inclusion/exclusion criteria of this study were retrospectively collected. VSs on the initial MRIs and their first follow‐up scans were manually contoured. Tumor volume and enlargement ratio were measured based on expert contours. A DMT model was constructed for jointly TS and TEP. The manually segmented VS volume on the initial scan and the tumor enlargement label (≥20% volumetric growth) were used as the ground truth for training and evaluating the TS and TEP modules, respectively.ResultsWe performed 5‐fold cross‐validation with the eligible patients (n = 103). Median segmentation dice coefficient, prediction sensitivity, specificity, accuracy, and area under the receiver operating characteristic curve (AUC) were measured and achieved the following values: 84.20%, 0.68, 0.78, 0.72, and 0.77, respectively. The segmentation result is significantly better than the separate TS network (dice coefficient of 83.13%, p = 0.03) and marginally lower than the state‐of‐the‐art segmentation model nnU‐Net (dice coefficient of 86.45%, p = 0.16). The TEP performance is significantly better than the single‐task prediction model (AUC = 0.60, p = 0.01) and marginally better than a radiomics‐based prediction model (AUC = 0.70, p = 0.17).ConclusionThe proposed DMT model is of higher learning efficiency and achieves promising performance on TEP and TS. The proposed technology has the potential to improve VS patient management.Level of EvidenceNA Laryngoscope, 133:2754–2760, 2023
Biosourced Monomers: Toward Sustainable Conjugated Polymers for Organic Electronics
Authors: Boivin Louis‐Philippe , Dupont William , Gendron David , Leclerc Mario 
Published: December 2022

AbstractOrganic electronic materials are starting to appear in various applications, but there are still hurdles to overcome before the average consumer can get them in their hands. Right now, most polymers in the field of organic electronics are made from petroleum derivatives. However, new sources of platform chemicals and monomers are being explored. This perspective article highlights ways that have been explored to avoid the use of petrochemicals and demonstrates new pathways that can be taken to increase the sustainability of conjugated polymers in organic electronics.
Properties of the support of solutions of a class of nonlinear evolution equations
Authors: Bustamante Eddye , Jiménez Urrea José 
Published: December 2022

AbstractIn this work we consider equations of the form
where P is any polynomial without constant term, and G is any polynomial without constant or linear terms. We prove that if u is a sufficiently smooth solution of the equation, such that for some , then there exists such that for every . Then, as an example of the application of this result, we employ it to show a unique continuation principle for the Kawahara equation,
and for the generalized KdV hierarchy
Clinical proteomics towards multiomics in cancer
Authors: Creighton Chad J. 
Published: December 2022

AbstractRecent technological advancements in mass spectrometry (MS)‐based proteomics technologies have accelerated its application to study greater and greater numbers of human tumor specimens. Over the last several years, the Clinical Proteomic Tumor Analysis Consortium, the International Cancer Proteogenome Consortium, and others have generated MS‐based proteomic profiling data combined with corresponding multiomics data on thousands of human tumors to date. Proteomic data sets in the public domain can be re‐examined by other researchers with different questions in mind from what the original studies explored. In this review, we examine the increasing role of proteomics in studying cancer, along with the potential for previous studies and their associated data sets to contribute to improving the diagnosis and treatment of cancer in the clinical setting. We also explore publicly available proteomics and multi‐omics data from cancer cell line models to show how such data may aid in identifying therapeutic strategies for cancer subsets.
Labor allocation: How environmental regulation promotes industrial structure
Authors: Lin Chun , Cui Gengrui , Sun Yingjie 
Published: December 2022

AbstractUsing the panel data of China from 2007 to 2016, this paper explores the relationship between environmental regulation and industrial structure upgrading. The results show that environmental regulation has a causally positive impact on the upgrading of industrial structure. To explain the positive causal effect of environmental regulation, we adopt the mediation effect method and then confirm that allocated labor rather than technological innovation is a significant channel by which such regulation affects industrial structure upgrading. Ultimately, this paper complements the existing economic literature by justifying that labor allocation is a key mechanism to upgrade industrial structure in China.
Managing prolific sows in tropical environments
Authors: Tummaruk Padet , De Rensis Fabio , Kirkwood Roy N. 
Published: December 2022

AbstractLitter size in modern sows has been dramatically improved in recent decades by genetic selection for highly prolific sows. In a tropical environment, the average total number of pigs born and number born alive are reported to be as high as 17.2 and 15.1 piglets per litter, respectively. Therefore, the new production target in many herds aims to achieve 30–40 pigs weaned per sow per year. Despite the improvements in litter size, the mean preweaning piglet mortality rate remains high, at between 10% and 20%, in major pig‐producing countries. A sufficient daily feed intake by lactating sows is important for high milk production as sow milk yield is the limiting factor for piglet growth rate. Heat stress, which can occur when the ambient temperatures rise above 25°C, is one of the major problems that decreases daily feed intake and compromises milk yield. Therefore, it is necessary to encourage high feed intakes to achieve high milk yields. However, even with high nutrient intakes, productivity can be constrained by intestinal barrier function, limiting digestive ability, and allowing potential pathogens and/or toxins to become systemic. This is more likely greater under tropical conditions because of heat stress, exacerbating sow fertility problems. Underpinning sow herd performance, including responses to environmental challenges, is the selection of appropriate gilts, for example, selection and management for early puberty, thus presumably selecting the more fertile gilts and the correct management of lactation to improve the number of weaned piglets are some of the key factors for future reproductive efficiency of the farm under tropical conditions.
Singlet‐exciton optics and phonon‐mediated dynamics in oligoacene semiconductor crystals
Authors: Thompson Joshua J. P. , Muth Dominik , Anhäuser Sebastian , Bischof Daniel , Gerhard Marina , Witte Gregor , Malic Ermin 
Published: December 2022

AbstractOrganic semiconductor crystals stand out as an efficient, cheap, and diverse platform for realizing optoelectronic applications. The optical response of these crystals is governed by a rich tapestry of exciton physics. So far, little is known on the phonon‐driven singlet‐exciton dynamics in this class of materials. In this joint theory–experiment work, we combine the fabrication of a high‐quality oligoacene semiconductor crystal and characterization via photoluminescence measurements with a sophisticated approach to the microscopic modeling in these crystals. This allows us to investigate singlet‐exciton optics and dynamics. We predict phonon‐bottleneck effects in pentacene crystals, and find that dark excitons act as crucial phonon‐mediated relaxation scattering channels in both pentacene and tetracene. While the efficient singlet fission in pentacene crystals hampers the experimental observation of this bottleneck effect, we reveal both in theory and experiment a distinct polarization and temperature dependence in absorption and photoluminescence spectra of tetracene crystals, including microscopic origin of exciton linewidths, the activation of the higher Davydov states at large temperatures, and polarization‐dependent quenching of specific exciton resonances. Our joint theory–experiment study represents a significant advance in microscopic understanding of singlet‐exciton optics and dynamics in oligoacene crystals.Key points
Compare microscopic modeling to spectroscopic measurements of excitons in oligoacene crystals.
Track the singlet‐exciton population and optical spectra following phonon‐mediated relaxation.
Predict a phonon‐bottleneck effect in pentacene that is absent in tetracene.
Diagnosis and management of isolated neutropenia: A survey of pediatric hematologist oncologists
Authors: Gunn Elizabeth , Powers Jacquelyn M. , Rahman AKM Fazlur , Bemrich‐Stolz Christina , Mennemeyer Stephen , Lebensburger Jeffrey D. , Wilson Hope P. 
Published: December 2022

AbstractBackgroundIsolated neutropenia is a common referral to pediatric hematology oncology (PHO) physicians. There are no established consensus guidelines in the diagnosis and management of patients with isolated, asymptomatic, and incidentally discovered neutropenia.MethodsA survey was distributed to PHO physicians on the American Society of Pediatric Hematology Oncology member discussion page to determine the common diagnostic and management decisions regarding patients with isolated neutropenia and to explore beliefs regarding the term “benign ethnic neutropenia.”ResultsOne hundred twenty‐six PHO attending physicians completed the survey. The most common tests reportedly ordered for this patient population included complete blood cell count (CBC) (98%), peripheral smear (75%), antineutrophil antibody testing (29%), and immunoglobulins (24%). Providers were more likely to order an antineutrophil antibody in toddlers (p = .0085), and antinuclear antibody (ANA) panels in adolescents (p < .001). Half of providers do not request additional CBCs prior to their initial consultation, and most suggest referring patients with mild neutropenia after confirming a declining absolute neutrophil count (ANC) (51%). The three most important factors influencing ongoing follow‐up included: history of recurrent/severe infections (98%), family history of blood disorders (98%), and more severe/progressively worsening neutropenia (97%). Seventy percent of respondents have diagnosed patients with “benign ethnic neutropenia,” and 75% support replacement of the term to “typical neutrophil count with Fy(a‐/b‐) status,” if confirmed with red cell phenotyping.ConclusionWe identified practice patterns of PHO physicians for the diagnosis and management of patients referred for asymptomatic and isolated neutropenia. These data provide the framework to conduct cost‐effectiveness studies.