bluuebunny/crossref_metadata_2025_split huggingface dataset:
Crustacés (Decapoda, Stomatopoda) dans la zone mésophotique corallienne de Mayotte (Sud-Ouest Océan Indien)
Authors: POUPIN Joseph , BARATHIEU Gabriel , KONIECZNY Olivier , MULOCHAU Thierry 
Published: May 2022

Des plongées techniques (TEK) en recycleur et mélanges gazeux spéciaux ont été réalisées autour de l’île de Mayotte sur les pentes externes récifales à des profondeurs comprises entre 50 et 120 m, et plus particulièrement aux alentours de 70-80 m, de 2017 à 2020. L’objectif de ces plongées était de réaliser un premier inventaire faunistique de la zone mésophotique, difficile d’accès et encore mal connue. Ce travail présente les résultats obtenus pour le groupe des Crustacés Décapodes et Stomatopodes avec au total 44 espèces photographiées en haute définition, dont 30 déterminées avec confiance, sept avec doute et sept identifiées provisoirement, peut-être nouvelles pour la nomenclature taxonomique. Les crevettes carides (16 espèces), les anomoures (15 espèces) et les crabes (sept espèces) sont les trois taxons les mieux représentés. Les stomatopodes, crevettes sténopides, langoustines et langoustes comptent chacun deux espèces. Ces observations permettent d’ajouter 32 nouvelles espèces à la faune mahoraise, dont quatre signalements nouveaux pour l’océan Indien. Les espèces sont présentées dans une liste illustrée avec une sélection de photographies. La liste est documentée avec indication des travaux ou guides consultés, des commentaires sur les déterminations et la mise à jour des distributions géographiques et bathymétriques. Pour 15 espèces traditionnellement observées sur des petits fonds (< 50 m), la profondeur maximale est augmentée entre 3 et 45 m. Plus de la moitié des espèces sont des formes libres (26 espèces). Les autres vivent en association avec les coraux ou hydraires (12 espèces), échinodermes (trois espèces), poissons (deux espèces) et éponges (une espèce). Quelques espèces sont à tendance cavernicole, observées dans des grottes ou sous des surplombs. À partir des données d’inventaire des Crustacés Décapodes de l’outre-mer tropical français, 212 espèces sont identifiées comme potentiellement présentes dans la zone mésophotique de Mayotte. Le présent inventaire de 44 espèces est donc assez modeste mais les photographies réalisées in situ permettent de mettre en évidence certaines associations ou modes de vie qui n’étaient pas soupçonnés avec les moyens d’étude classiques. À l’avenir, les observations pourront être améliorées en accordant plus d’importance aux coquilles, parfois occupées par des Bernard l’ermite non déterminés car photographiés de trop loin, et/ou en effectuant des plongées de nuit, lorsque les Crustacés sont plus actifs. La poursuite de ce programme de recherche prévoit la récolte de quelques spécimens, en particulier pour les espèces reconnues comme probablement nouvelles pour la nomenclature taxonomique.
Evaluation of Individualized Pain Plans for Children With Sickle Cell Disease Admitted for Vaso-occlusive Crisis at Riley Hospital for Children
Authors: Arends Alexandria M. , Perez Anne , Wilder Christina , Jacob Seethal A. 
Published: May 2022

OBJECTIVE
Vaso-occlusive crisis (VOC) is the most common problem reported by patients with sickle cell disease (SCD). The objective of this study was to evaluate the impact of individualized pain plans in pediatric patients with SCD admitted for VOC.

METHODS
This was a pre- and post-study of patients with SCD admitted to Riley Hospital for Children for VOC from July 1, 2019, through July 1, 2020. The primary outcome was length of inpatient stay for VOC. Secondary outcomes included final pain score, days on scheduled opioids, days on breakthrough opioids, and average morphine milligram equivalents (MME) used per day.

RESULTS
Nine patients were included. The mean age was 16 years (range, 10–20 years). Key clinical findings were decreases in median [IQR] for final pain scores (7 [4.5–9] vs 6 [2.5–8], p = 0.396) and number of days of breakthrough opioid use (5 [3–8] vs 4 [2.5–5.5], p = 0.233). Following implementation of an individualized pain plan, there was an increase in median average MME per day (65.94 [53.1–97.7] vs 82.85 [41–114.3], p = 0.844). Median length of stay and days on scheduled opioids remained the same.

CONCLUSIONS
This study demonstrated that use of individualized pain plans in a small population of patients with SCD might result in decreased pain scores and decreased days on breakthrough opioids.
A Multicenter Analysis of Changes in Pediatric Antibiotic Susceptibilities Among Staphylococcus aureus and Pseudomonas aeruginosa Isolates: 2014–2018
Authors: Stultz Jeremy S. , Benefield Emily , Lee Kelley R. , Bashqoy Ferras , Pakyz Amy L. 
Published: May 2022

OBJECTIVE
To describe antibiotic susceptibilities for Staphylococcus aureus and Pseudomonas aeruginosa among pediatric institutions in 2018. To assess correlations between antibiotic utilization and susceptibilities.

METHODS
Institutional antibiograms from 2018 were compiled among 13 institutions via a survey. Resistant pathogens and antibiotic days of therapy/1000 patient days (PD) were collected from 6 institutions over 5 years. Correlations were assessed as pooled data among all institutions and relative changes within individual institutions.

RESULTS
All 8552 S aureus isolates in 2018 were vancomycin susceptible and 40.1% were methicillin resistant (MRSA). Among MRSA, 96.3% and 78.8% were susceptible to trimethoprim/sulfamethoxazole and clindamycin, respectively. Pooled yearly MRSA/1000 PD decreased from 2014–2018 and correlated with pooled yearly decreases in vancomycin utilization (R = 0.983, p = 0.003). Institutional relative decreases in vancomycin utilization from 2014–2018 did not correlate with institutional relative decreases in MRSA susceptibility (R = −0.659, p = 0.16). Susceptibility to meropenem was 90.9% among 2315 P aeruginosa isolates in 2018. Antipseudomonal beta-lactam susceptibility ranged from 89.4% to 92.3%. Pooled yearly meropenem-resistant P aeruginosa/1000 PD and meropenem utilization did not significantly decrease over time or correlate (both p &gt; 0.6). Institutional relative change in meropenem utilization from 2013–2017 correlated with the institutional relative change in P aeruginosa susceptibility to meropenem from 2014–2018 (Rs = −0.89, p = 0.019).

CONCLUSIONS
Among included institutions, the burden of MRSA decreased over time. Institutional MRSA prevalence did not consistently correlate with institutional vancomycin utilization. Institutional changes in meropenem utilization correlated with P aeruginosa susceptibility the following year. Pooled analyses did not illustrate this correlation, likely owing to variability in utilization between institutions.
National Intravenous Acetaminophen Use in Pediatric Inpatients From 2011–2016
Authors: Patel Anita K. , Gai Jiaxiang , Trujillo-Rivera Eduardo , Faruqe Farhana , Kim Dongkyu , Bost James E. , Pollack Murray M. 
Published: May 2022

OBJECTIVE
To 1) determine current intravenous (IV) acetaminophen use in pediatric inpatients; and 2) determine the association between opioid medication duration when used with or without IV acetaminophen.

METHODS
A retrospective analysis of pediatric inpatients exposed to IV acetaminophen from January 2011 to June 2016, using the national database Health Facts.

RESULTS
Eighteen thousand one hundred ninety-seven (2.0%) of 893,293 pediatric inpatients received IV acetaminophen for a median of 14 doses per patient (IQR, 8–56). A greater proportion of IV acetaminophen patients were admitted to the intensive care unit (ICU) (14.8% vs 5.1%, p &lt; 0.0001), received positive pressure ventilation (2.0% vs 1.5%, p &lt; 0.0001), had a higher hospital mortality rate (0.9% vs 0.3%, p &lt; 0.0001), and were operative (35.5% vs 12.8%, p &lt; 0.001) than those not receiving IV acetaminophen. The most common operations associated with IV acetaminophen use were musculoskeletal and digestive system operations. Prescription of IV acetaminophen increased over time, both in prescription rates and number of per patient doses. Of the 18,197 patients prescribed IV acetaminophen, 16,241 (89.2%) also were prescribed opioids during their hospitalization. A multivariate analysis revealed patients prescribed both IV acetaminophen and opioids had a 54.8% increase in opioid duration as compared with patients who received opioids alone.

CONCLUSIONS
This is the first study to assess IV acetaminophen prescription practices for pediatric inpatients. Intravenous acetaminophen prescription was greater in the non-operative pediatric inpatient population than operative patients. Intravenous acetaminophen prescription was associated with an increase in opioid duration as compared with patients who received opioids alone, suggesting that it is commonly used to supplement opioids for pain relief.
Possibilidades didáticas do ensino virtual em iluminação cênica
Authors: Alencar Wesdey 
Published: May 2022

Este artigo analisa a experiência sobre o ensino em iluminação cênica realizado de modo virtual, explorando as “novas” possibilidades e o uso de ferramentas didáticas e pedagógicas neste processo de ensino. É explorado no texto, os procedimentos metodológicos e teorias, utilizadas pelo professor de iluminação, Ciel Carvalho, no planejamento e execução do curso “O Movimento da Luz Como Elemento Cocriador na Dança”. As aulas foram realizadas em abril de 2021, por meio da plataforma online google meet, dentro do projeto ateliês de criação do Arte Urgente. Neste artigo são relatadas as dificuldades, inseguranças e superações do ensino virtual em iluminação cênica, em curso ministrado durante a pandemia da Covid-19. No texto, é relatado, através de entrevistas e análise de dados, a experiência do processo criativo realizado pelos(as) alunos(as) e professor do curso, no qual o conceito de luz presente, de TEIXEIRA (2019) foi utilizado como dispositivo criador da dramaturgia de vídeos danças/performance.
Bacterial Bloodstream Infections – Prevalence, Etiology, and their Antibiotic Susceptibility Profile in Mumbai City
Authors: Dave Mukti , Shaikh Nasheet , Pawar Sakshi , Bangde Sonal 
Published: May 2022

Aim: To study bacterial bloodstream infections concerning prevalence, etiology, and antibiotic susceptibility profile of pathogens in Mumbai City
Study Design: Retrospective study
Place and Duration of Study: Department of Microbiology, InfeXn Laboratories Pvt. Ltd., Thane
One-year duration: January 2019- December 2019
Methodology: The present retrospective study was performed on around 9397 adult and pediatric blood samples by using a rapid, accurate, and high throughput automated blood culture system for timely diagnosis of BSI.
Results and Discussion: Bloodstream infection (BSIs) is considered a medical emergency as it is associated with high morbidity and mortality worldwide. The prevalence of BSI-causing bacteria and their Antibiotic susceptibility (AST) profile vary as per age, season, geographical location, etc. With a large cohort of 9397 samples, the total positivity rate was 17.47 % with gram-negative bacteria (67.69%) being more common than gram-positive (32.30%) in both adult and pediatric populations, with a peak in the Monsoon season. Escherichia coli (26.17%) and Klebsiella pneumoniae (27.31%) were the most isolated pathogens in the adult and pediatric populations, respectively. Carbapenemase production was seen highest in the non-fermentor group of bacteria (42.85%) whereas ESBL production was seen more in the Enterobacterals group (53%). Except for MRSA, gram-positive bacteria showed a very good susceptibility profile to the listed antibiotics. There was no case of VRE observed in the study.
Conclusion: The study highlights the need for regular monitoring of BSI-causing bacteria and their antibiogram, which can help better to formulate empirical treatment strategies, controlled use of antibiotics, monitoring trends in drug resistance, and antibiotic stewardship.
Aggressiveness in a subtropical shorebird's nest defense is adjusted to the predator species and shared by conspecifics
Authors: Brynychová Kateřina , Sládeček Martin , Pešková Lucie , Chajma Petr , Firlová Veronika , Elhassan Esmat , Vozabulová Eva , Janatová Veronika , Almuhery Aisha , Šálek Miroslav 
Published: May 2022

AbstractAggression is an important component of an animal's defense when protecting offspring from predators. Ground nesting birds use a variety of defense strategies. However, their choice according to situation context is poorly known, especially in nonpasserines and in the subtropics and tropics. The ability to distinguish between differently dangerous predator species and the opportunity to share defense with conspecifics are potentially important but little‐studied aspects of nest defense strategy. We experimentally studied the nest defense of Red‐Wattled Lapwing in an individually marked population in a desert area near Dubai, UAE. We used three stuffed models representing 1) a predator dangerous both to adults and to nests (a cat), 2) a nest predator (a raven), and 3) a harmless reference model (a moorhen). We confirmed that the lapwings distinguished between predator species (being most aggressive toward the cat, and least aggressive toward the moorhen) and adjusted their defense strategy accordingly. In addition, conspecific visitors play a variety of roles in parents' defense strategy. They can strengthen the parental reaction, or they can assist in distracting a predator. The visitors included not only nesting neighbors but also nonbreeding floaters. Both parents participated in nest defense to a similar extent, regardless of incubation stage and ambient temperature. This study provides new insight into the complexity of the defensive patterns in ground‐nesting birds inhabiting a hot environment. Comparative experimental research on a range of environments, with various bird species and predator models, can help us to understand the drivers of these defensive behavioral patterns.
The µ‐Opioid Receptor in Cancer and Its Role in Perineural Invasion: A Short Review and New Evidence
Authors: Cata Juan P. , Uhelski Megan L. , Gorur Aysegul , Bhoir Siddhant , Ilsin Nisa , Dougherty Patrick M. 
Published: May 2022

AbstractCancer is a significant public health problem worldwide. While there has been a steady decrease in the cancer death rate over the last two decades, the number of survivors has increased and, thus, cancer‐related sequela. Pain affects the life of patients with cancer and survivors. Prescription opioids continue as the analgesic of choice to treat moderate‐to‐severe cancer‐related pain. There has been controversy on whether opioids impact cancer progression by acting on cancer cells or the tumor microenvironment. The μ‐opioid receptor is the site of action of prescription opioids. This receptor can participate in an important mechanism of cancer spread, such as perineural invasion. In this review, current evidence on the role of the μ‐opioid receptor in cancer growth is summarized and preliminary evidence about its effect on the cross‐talk between sensory neurons and malignant cells is provided.
Towards integrated wind farm control: Interfacing farm flow and power plant controls
Authors: Kölle Konstanze , Göçmen Tuhfe , Garcia‐Rosa Paula B. , Petrović Vlaho , Eguinoa Irene , Vrana Til Kristian , Long Qian , Pettas Vasilis , Anand Abhinav , Barlas Thanasis K. , Cutululis Nicolaos , Manjock Andreas , Tande John Olav , Ruisi Renzo , Bossanyi Ervin 
Published: May 2022

AbstractConcepts for control of wind farms (WFs) can be clustered into two distinct concepts, namely, wind power plant control (WPPC) and wind farm flow control (WFFC). WPPC is concerned with the connection to the power system, compliance with grid codes, and provision of power system services. This comprises the traditional way of operating a WF without consideration of aerodynamic turbine interaction. However, flow phenomena like wake effects can have a large impact on the overall performance of the WF. WFFC considers such aerodynamic phenomena in the WF operation. It can be viewed as a new feature that shall be integrated with the existing control functions. The interaction of these different control concepts is discussed in this article, leading to an identification of the challenges whose solutions will contribute to a successful integration of electrical system and aerodynamic aspects of WF control.
Exploring ibuprofen derivatives as α‐glucosidase and lipoxygenase inhibitors: Cytotoxicity and in silico studies
Authors: Daud Saima , Abid Obaid‐ur‐Rahman , Sardar Asma , Abdullah Shawana , Shahid Wardah , Ashraf Muhammad , Ejaz Syeda Abida , Saeed Amna , Shah Basit Ali , Niaz Basit 
Published: May 2022

AbstractThis study reports the synthesis of a series of ibuprofen derivatives, including thiosemicarbazides 4a–f, 1,3,4‐oxadiazoles 5a–f, 1,3,4‐thiadiazoles 6a–f, 1,2,4‐triazoles 7a–f, and their S‐alkylated derivatives 8a–d. All of the newly synthesized derivatives were analyzed using 1H NMR, 13C NMR spectroscopy, and high‐resolution mass spectra (electron ionization) spectrometry. These synthetic molecules were examined for their in vitro baking yeast α‐glucosidase and soybean 15‐lipoxygenase (15‐LOX) inhibition and cell viability studies. The results revealed that the compounds N‐(3,4‐dichlorophenyl)−5‐[1‐(4‐isobutylphenyl)ethyl]‐1,3,4‐oxadiazol‐2‐amine 5f (IC50 3.05 ± 1.23 µM) and N‐(3‐fluorophenyl)‐5‐[1‐(4‐isobutylphenyl)ethyl]‐1,3,4‐oxadiazol‐2‐amine 5b (IC50 3.12 ± 1.21 µM) were the most potent with respect to the α‐glucosidase enzyme while in case of 15‐LOX, the compound 4‐(2,4‐dichlorophenyl)‐1‐[2‐(4‐isobutylphenyl)propanoyl]thiosemicarbazide 4e showed potent inhibition with an IC50 value of 55.41 ± 0.41 µM. All these compounds were found least toxic by displaying a blood mononuclear cell viability value of 69.2%–97.8% by the MTT assay compared to the standards when assayed at 0.25 mM concentration. Molecular docking analyses were conducted to evaluate the inhibition profiles of these derivatives against the said enzymes and the data supported the in vitro profiles.
Surface Functionalization of LiNi7.0Co0.15Mn0.15O2 with Fumed Li2ZrO3 via a Cost‐Effective Dry‐Coating Process for Enhanced Performance in Solid‐State Batteries
Authors: Cangaz Sahin , Hippauf Felix , Takata Ryo , Schmidt Franz , Dörfler Susanne , Kaskel Stefan 
Published: May 2022

AbstractApplying a thin film coating is a vital strategy to enhance long term and interface stability of Ni‐rich layered oxide cathode materials (NRLOs), especially when they are matched with sulfidic solid electrolytes (SSEs) in solid‐state batteries (SSBs). The coating prevents direct contact between the cathode active material (CAM) and the SSE, shielding against parasitic side reactions at the cathode electrolyte interface (CEI). Conventional coatings are based on wet‐chemical methods and therefore harmful to the environment and require long‐lasting processing and high costs. In this study, we present a versatile, facile and highly‐scalable dry‐coating method (with suitable equipment up to 500 kg per batch) successfully employed for both multi‐ and single‐crystalline LiNi0.70Mn0.15Co0.15O2 (NCM70) particles by fumed Li2ZrO3 nanostructured particles (LZONPs) via high intensity mixing process. The resulting porous coating layer stays firmly attached at the CAM particle surface without a need of post‐calcination step at elevated temperatures. The electrochemical testing results signify enhanced rate capability up to 1.5 mA cm−2 for both particle types and cyclic stability up to 650 cycles with a capacity retention of 86.1 % for single‐crystalline NCM70. We attribute the enhanced performance to the reduced CEI reactions as cathodic charge transfer resistance depressed significantly after dry‐coating by LZONPs, being an important step towards sulfidic solid‐state batteries.
Potential eating disorder exhibited with daytime functional vulnerabilities associated with sleep problems in Japanese adolescents: A cross‐sectional study
Authors: Hirai Takaharu , Mitobe Yuta , Hirai Hiromi , Takeda Momoka , Hayashi Mikiko 
Published: May 2022

AbstractObjectivesEating disorders (ED) are serious psychiatric disorders that affect individuals, especially adolescents. It has been suggested that nonclinical ED‐like characteristics are related to sleep problems. We conducted a survey of Japanese adolescents to investigate this claim.MethodIn this cross‐sectional study, 398 adolescents aged 12–18 years responded to a self‐administered questionnaire survey. We used the Eating Attitudes Test‐26 (EAT‐26) and the Athens Insomnia Scale (AIS) to measure potential ED and sleep problems, respectively.ResultsAdolescents with potential ED had significantly higher daytime functional vulnerability potentially associated with sleep problems than those without ED. In particular, problems with a sense of well‐being and physical and mental functioning during the day were significant. In contrast, no significant associations were found between potential ED and sleep initiation, awakenings during the night, early morning awakening, total sleep duration, or overall quality of sleep. Finally, nocturnal and daytime sleep scores were significantly associated with dieting, bulimia, and oral control EAT‐26 subscores.DiscussionParticipants with possible ED experienced problems related to well‐being and mental and physical functioning, which are indicators of daytime functional vulnerability potentially associated with sleep problems. Further, adolescents with more severe ED characteristics are more likely to have a higher degree of daytime psychological vulnerability potentially attributable to sleep problems. The study suggested that professionals treating adolescent mental health issues need an approach that comprehensively integrates both sleep problems and potential ED.
TIPTAB: A tangible interactive projection tabletop for virtual experiments
Authors: Yuan Qingshu , Wang Ruonan , Pan Zhigeng , Meng QianYu , Xu Shuchang , Wang Zihan , Liu Jiaxin 
Published: May 2022

AbstractVirtual experiments are a new way of doing experiments. A visible difference between virtual and real experiments is the interaction mode. Such a difference causes unfamiliarity and induces unnecessary cognitive load and inefficiency during learning. The objective of the research is to reduce the interactive operation difference between virtual and real experiments as much as possible. TIPTAB, a tangible interactive projection tabletop, is proposed for virtual experiments. A depth camera is used to detect tangible objects in the real environment. These objects are printed by three‐dimensional (3D) printers in advance and tracked in real‐time. The tracked 3D poses are then used as inputs for further experiments. Both object textures and scene contents are augmented by projectors, and thus the virtual presentation of digital space is seamlessly registered and fused with physical space. An infrared (IR) camera and an IR transmitter are used to detect finger touch operations on the tabletop. During experimental learning, students can interact without wearing any devices as they do in real experiments, which greatly reduces their interaction burdens. Experimental results show that the proposed method is more efficient compared with other representative interaction methods. Based on the cognitive load theory and the statistical data, TIPTAB has a low cognitive load for students during virtual experiments. Questionnaire survey results also indicate that TIPTAB offers a good learning experience.