bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the spatial distribution and dynamic succession of microbial community and quality properties during fermentation in Chinese medium‐temperature Daqu
Authors: Ding Li , Zhao Meng‐Meng , Zhao Xiao‐Fang , Chen Guo‐Yue , Jiang Qian‐Tao , Liu Miao , Xiong Yan‐fei , Zhang Xiu , Wang Xiao‐Jun , Wei Yu‐Ming , Zheng You‐Liang , Li Wei 
Published: November 2022

AbstractThe spatial characterization of qualities and microbial community of Chinese Baijiu Daqu during solid‐state fermentation remains unclear. The physicochemical indexes and microbial of the core (CDB) and the surface (SDB) of medium‐temperature Daqu (MT‐Daqu) at eight fermenting stages were investigated. The results indicated the difference in physicochemical indices, enzymatic activities, and starch granule fracture between the CDB and SDB. The dominant bacteria were Lactobacillus, Weissella, Pediococcus, and Methylobacterium in the SDB, as Staphylococcus, Bacillus, Thermoactinomyces, and Undibacterium in the CDB. The dominant fungi were Dipodascus, Wickerhamomyces, Hyphopichia, and Saccharomyces in the SDB, like Aspergillus, Thermoacscus, Theromyces, and Candida in the CDB. Redundancy analysis (RDA) showed that different factors strongly affected the bacteria and fungi in the SDB and CDB, respectively. The temperature, moisture, and starch content were the critical factors for the microbial composition of Daqu. This study provides further valuable information for knowing the fermentation mechanism of MT‐Daqu.Novelty impact statement

This study provided information on the spatial characterization of qualities and microbial community of Chinese Baijiu Daqu during solid‐state fermentation of medium‐temperature Daqu (MT‐Daqu).

This study revealed the difference between the surface brick samples (SDB) and the core brick samples (CDB) in the fermentation process of Daqu, which increased the diversity of fermentation.

The temperature, moisture, and starch content were the critical factors in influencing the difference between Daqu microorganisms of the core (CDB) and the surface (SDB) of medium‐temperature Daqu (MT‐Daqu).
Measuring working alliance and technical alliance from the perspective of healthcare professionals working with people with mild intellectual disabilities: adaptation, factor structure and reliability
Authors: Oudshoorn C. E. M. , Frielink N. , Riper H. , Embregts P. J. C. M. 
Published: November 2022

AbstractBackgroundThe establishment of a valuable and meaningful working alliance between people with mild intellectual disabilities (IDs) and healthcare professionals is critically important for improving both the quality of life and impact of therapy for people with mild IDs. Measuring the working alliance as a treatment or support component is therefore of utmost relevance. In light of the increased use of eHealth tools, it is also essential to measure the alliance using these tools, which is referred to as technical alliance. There was a lack of validation of these two measurements for healthcare professionals working with people with mild IDs, which this study sought to address.MethodBoth the validated Working Alliance Inventory – Short Form – MID (WAI‐SF‐MID) and Technical Alliance Inventory – Short Form – MID (TAI‐SF‐MID) for general patient populations were adapted for healthcare professionals working with people with mild IDs. A two‐step approach was conducted to systematically adapt both measurements with an expert group of healthcare professionals. Confirmatory factor analysis was conducted to test a three‐factor structure for both the WAI‐SF‐MID (N = 199) and the TAI‐SF‐MID (N = 139), and internal consistency was determined for both scales.ResultsAn acceptable‐to‐good model fit was found for both the WAI‐SF‐MID and the TAI‐SF‐MID; confirmatory factor analysis confirmed a three‐factor model for both measurements. Cronbach's alpha and McDonald's omega were excellent for both total scales (≥0.90) and acceptable to good for sub‐scales of both versions.ConclusionBoth the WAI‐SF‐MID and the TAI‐SF‐MID are promising measurements for determining healthcare professionals' perspective on the (digital) working alliance with people with mild IDs.
Experiences of Mothers Participating in a Mother–Child Video Therapy Program
Authors: Hackley Barbara , Hammer Monica , Barnhart Erika , Abramowitz Kelly , Chinitz Emily , Sharma Chanchal , Shapiro Alan 
Published: November 2022

IntroductionResponsive and sensitive parenting promotes the development of self‐regulation and lowers stress in children, which in turn is associated with greater educational and economic achievement and better physical and emotional health later in life. Dyadic parent–child video‐feedback programs can help parents learn effective parenting skills, yet these programs are estimated to retain only about half of eligible participants. Programs vary widely, and little is known about what is valued by parents who do complete these programs. The purpose of this qualitative study was to understand the goals, experiences, and outcomes important to mothers who completed a video‐feedback program.MethodsTranscripts of exit interviews of participants in a video‐feedback program (N = 31) were analyzed using qualitative description methodology. Trustworthiness was achieved through deep engagement with the material, following an iterative process in analyzing transcripts, and member checks to confirm results.ResultsMothers enrolled in the program to better understand their child, help their child learn, and to develop closer connections with their child. Elements of the program that helped mothers achieve these goals were (1) positive feedback and support by the therapist, (2) dedicated one‐on‐one time spent with their infant, (3) help with concrete needs, and (4) learning from watching videotaped play sessions. As a result, mothers reported greater confidence as caregivers, use of more responsive and sensitive parenting strategies, and improvements in their children's behaviors and their own mental health.DiscussionIncorporating elements of the program found to be most useful in this study into video‐feedback programs may make video‐feedback programs more attractive to parents and increase retention. Midwives and women's health care providers may incorporate elements of the program into their clinical practice and advocacy, with special attention to elements most valued by parents themselves.
Patterns and predictors of change in energy and mood around a vacation from the workplace: Distinguishing the effects of supplemental work activity and work‐related perseverative cognition
Authors: Flaxman Paul E. , Stride Christopher B. , Newman Sonja A. , Ménard Julie 
Published: November 2022

AbstractThis study contributes to the vacation literature by exploring predictors of change in school teachers' negative affective states around a 2‐week (Christmas) vacation. Drawing from a combination of self‐regulatory and effort‐recovery theoretical principles, we hypothesized that supplemental work activity during the vacation might have some positive consequences for mood state, while simultaneously impairing the ability to recover from work‐related exhaustion. Ninety teachers completed measures across eight consecutive weeks, spanning the period before, during and after vacation (710 observations in total). Teachers' weekly levels of emotional exhaustion, anxious mood and depressed mood decreased significantly from before to during the vacation. Following the vacation, anxious mood showed the most rapid rate of increase, returning to its prevacation level within 2 weeks of work resumption. Exhaustion and depressed mood re‐emerged more gradually across 4 consecutive weeks following the vacation. Supplemental work activity during the vacation was associated with weaker recovery from exhaustion, but did not exhibit a detrimental relationship with change in anxious or depressed mood. Of note, supplemental working during the vacation was associated with a less pronounced re‐emergence of anxious mood after the vacation. Work‐related perseverative cognition (worry and rumination) during the vacation impeded energy restoration and mood repair and was related to faster fade out of beneficial vacation effects. These findings demonstrate the utility of examining discrete energy and mood states in respite research, reveal the mixed functions of engaging in supplemental work activity during vacations and highlight the harmful impact of perseverative cognition on the recovery from work process.
Outcome of chronic inflammatory enteropathy in cats: 65 cases (2011‐2021)
Authors: Bandara Y. , Priestnall S. L. , Chang Y. M. , Kathrani A. 
Published: November 2022

ObjectivesFeline chronic inflammatory enteropathy is an idiopathic disease with limited information on variables that might affect treatment outcome and survival. The aim of this study was to determine if clinicopathological variables were associated with death due to gastrointestinal disease in cats with chronic inflammatory enteropathy.Materials and MethodsThree medical records databases were retrospectively searched for cats diagnosed with chronic inflammatory enteropathy at the Royal Veterinary College between June 2008 and November 2021. Intestinal biopsy specimens of eligible cases were re‐reviewed by one board‐certified veterinary pathologist. Outcome information was obtained by contact with the referring veterinary surgeon. Two univariable binary logistic regression models and a Fisher's exact test were performed to assess the association between the outcome of death due to gastrointestinal disease or its short‐term survival (≤ versus >1 year) with clinicopathological variables and the attainment of clinical remission.ResultsSixty‐five cats diagnosed with chronic inflammatory enteropathy between September 2011 and August 2021 were included in the study with follow‐up information available for 54 cats (83%). Of these 54 cats, 20 (37%) were euthanised due to gastrointestinal disease (median 129.5 days; range 8 to 2970 days). Twenty‐five (46%) cats were alive and in clinical remission (median 916 days; range 78 to 2113 days) with 16 (64%) diagnosed with food‐responsive enteropathy. Attaining clinical remission reduced the likelihood of subsequent death due to gastrointestinal disease.Clinical SignificanceMeasured physical and laboratory variables at the time of histopathological diagnosis of chronic inflammatory enteropathy were not predictors of death. Alternative diagnostic measures are required to definitively investigate outcome and survival in cats with chronic inflammatory enteropathy.
The impact of intrapartum and immediate post‐partum complications and newborn care practices on breastfeeding initiation in Ethiopia: A prospective cohort study
Authors: Mohammed Shamsudeen , Abukari Alhassan S. , Afaya Agani 
Published: November 2022

AbstractThis study aimed to investigate the impact of intrapartum and post‐partum complications and newborn care practices on early initiation of breastfeeding (EIBF). Data for the study came from a prospective cohort study in Ethiopia that recruited and followed pregnant and post‐partum women from 2019 to 2021. Resident enumerators conducted interviews at enrolment in 2019 and follow‐ups at 6 weeks, 6 months and 1 year post‐partum. The present analysis is based on data from the baseline survey and 6 weeks follow‐up. Multivariable logistic regression was used to estimate the effects of newborn care practices and intrapartum and post‐ partum complications on EIBF (the proportion of newborns who initiated breastfeeding within the first hour of birth). Overall, 2660 mother–infant pairs were included in this analysis. After adjustment, EIBF was less likely among women who experienced intrapartum haemorrhage (adjusted odds ratio [AOR]: 0.76, 95% confidence interval [CI]: 0.59–0.97), malpresentation (AOR: 0.46, 95% CI: 0.30–0.72) and convulsions (AOR: 0.48, 95% CI: 0.34–0.66) during childbirth. Mother–newborn skin‐to‐skin contact increased the likelihood of EIBF (AOR: 1.47, 95% CI: 1.11–1.94). Women who experienced post‐partum haemorrhage (AOR: 0.63, 95% CI: 0.47–0.84), retained placenta for more than 30 min (AOR: 0.36, 95% CI: 0.24–0.52) and convulsions after delivery (AOR: 0.57, 95% CI: 0.41–0.79) were less likely to initiate breastfeeding early. Also, women who had a caesarean birth (AOR: 0.28, 95% CI: 0.18–0.41), delivered outside of a healthcare facility (AOR: 0.70, 95% CI: 0.50–0.99) or had twin birth (AOR: 0.43, 95% CI: 0.22–0.85) were less likely to initiate breastfeeding early. Skin‐to‐skin contact should be encouraged whenever possible, and women with obstetric complications should be encouraged and supported to initiate breastfeeding early.
Co‐coverage of reproductive, maternal, newborn and child health interventions shows wide inequalities and is associated with child nutritional outcomes in Ethiopia (2005–2019)
Authors: Baye Kaleab , Laillou Arnaud , Chitekwe Stanley 
Published: November 2022

AbstractThe health system is the primary vehicle for the delivery of nutrition‐specific interventions that aim to reduce maternal and child malnutrition. The integration of nutrition interventions into existing health interventions is promising, but to ensure that no one is left behind requires that access to essential health services is equitably distributed. This study aims to assess trends and socioeconomic inequalities in coverage of reproductive, maternal, newborn and child health (RMNCH) and assess its association with child nutritional outcomes in Ethiopia. Using the Ethiopian Demographic and Health Survey (2005, 2011, 2016, and 2019), we estimated the coverage of RMNCH interventions in Ethiopia using the co‐coverage index, which is a count of the number of interventions accessed. We assessed the trend and inequalities in co‐coverage and evaluated its association with child nutritional outcomes like stunting, wasting, and minimum dietary diversity (MDD). The national co‐coverage index has shown a significant increase over the 2005–2019 period. However, all of the RMNCH interventions constituting the co‐coverage index showed a pro‐rich and pro‐urban distribution (p < 0.05). The highest inequality, based on the slope index of inequality (SII), was observed for skilled assistance during delivery (SII: 80.4%), followed by access to an improved source of drinking water (SII: 62.6%), and antenatal care visits (SII: 55.5%). The low coverage in RMNCH and the observed inequality were associated with stunting, wasting, and MDD. Reducing socioeconomic inequality in RMNCH is key to achieve the health, nutrition and equity‐related goals of the Sustainable Development Goals.
Metatranscriptomics reveals contrasting effects of elevation on the activity of bacteria and bacterial viruses in soil
Authors: Merges Dominik , Schmidt Alexandra , Schmitt Imke , Neuschulz Eike Lena , Dal Grande Francesco , Bálint Miklós 
Published: November 2022

AbstractSoil microbial diversity affects ecosystem functioning and global biogeochemical cycles. Soil bacterial communities catalyse a diversity of biogeochemical reactions and have thus sparked considerable scientific interest. One driver of bacterial community dynamics in natural ecosystems has so far been largely neglected: the predator–prey interactions between bacterial viruses (bacteriophages) and bacteria. To generate ground level knowledge on environmental drivers of these particular predator–prey dynamics, we propose an activity‐based ecological framework to simultaneous capture community dynamics of bacteria and bacteriophages in soils. An ecological framework and specifically the analyses of community dynamics across latitudinal and elevational gradients have been widely used in ecology to understand community‐wide responses of innumerable taxa to environmental change, in particular to climate. Here, we tested the hypothesis that the activity of bacteria and bacteriophages codeclines across an elevational gradient. We used metatranscriptomics to investigate bacterial and bacteriophage activity patterns at five sites across 400 elevational metres in the Swiss Alps in 2015 and 2017. We found that metabolic activity (transcription levels) of bacteria declined significantly with increasing elevation, but activity of bacteriophages did not. We showed that bacteriophages are consistently active in soil along the entire gradient, making bacteriophage activity patterns divergent from that of their putative bacterial prey. Future efforts will be necessary to link the environment‐activity relationship to predator–prey dynamics, and to understand the magnitude of viral contributions to carbon, nitrogen and phosphorus cycling when infection causes bacterial cell death, a process that may represent an overlooked component of soil biogeochemical cycles.
Inhibition of the 3‐hydroxy‐3‐methyl‐glutaryl‐CoA reductase diminishes the survival and size of chondrocytes during orofacial morphogenesis in zebrafish
Authors: Signore Iskra A. , Palma Karina , Soto Gabriela , Sepúlveda Santiago , Suazo José , Aránguiz Millisent , Colombo Alicia 
Published: November 2022

AbstractObjectivesThe 3‐hydroxy‐3‐methyl‐glutaryl‐CoA reductase (HMGCR) is the enzyme controlling the rate‐limiting step in the synthesis of cholesterol, sterols, and isoprenoids in the mevalonate biosynthetic pathway. Impaired function of HMGCR in zebrafish produces craniofacial malformations and orofacial cleft, mainly affecting the post‐migratory neural crest cells with little earlier effect. Here we investigate morphogenetic and cellular mechanisms underlying the generation of these malformations.MethodsThe morphology of chondrocytes in the lower jaw and the proliferation/apoptosis in the ethmoid plate were analysed in hmgcr1b mutants and in embryos treated with atorvastatin. In the ceratohyal of treated embryos, we measured the number and dimensions of chondrocytes. In the ethmoid plate, we performed proliferation and apoptosis assays to quantify the number of cells undergoing each process in both hmgcr1b mutants and pharmacologically treated embryos. All embryos were imaged using confocal microscopy and processed to obtain maximum intensity z‐projection.ResultsThe shortening of the ceratohyal is produced by a moderate reduction in the number of cells combined with isometric shrinkage of the chondrocytes. At the same time, the shortening of the ethmoid plate is due to a combination of a slightly diminished proliferation with massive abnormal apoptosis at the proliferation front.ConclusionHMGCR function is necessary for the normal survival and morphology of chondrocytes during condensation and chondrogenesis in the developing palate and jaw. Further studies are required to establish the pathways through which HMGCR acts on apoptosis, proliferation, and cell size during normal craniofacial development.
A negative emotional context disrupts the framing effect on outcome evaluation in decision making under uncertainty: An ERP study
Authors: Tao Ruiwen , Zhang Can , Zhao Hanxuan , Xu Yan , Han Tianqi , Dai Mengge , Zheng Kexin , Zhang Naifu , Xu Sihua 
Published: November 2022

AbstractThe framing effect refers to the phenomenon that different descriptions of the same option lead to a shift in the choice of the decision maker. Several studies have found that emotional contexts irrelevant to a decision in progress still influence the framing effect on decision making. However, little is known about the potential role of emotional contexts in the framing effect on outcome evaluation under uncertainty and the related neural mechanisms. The present study measured event‐related potentials (ERPs) to capture the time series of brain activities during the processing of gain‐ and loss‐framed choices and outcomes primed with neutral and negative emotional contexts. The results revealed that in the neutral emotional context, the P300 amplitudes following both positive and negative feedback were greater in the gain‐framed condition than those in the loss‐framed condition, demonstrating a framing effect, whereas in the negative emotional context, this effect was unstable and observed only following negative feedback. In contrast, regardless of whether the feedback was positive or negative, the framing effect on the feedback‐related negativity (FRN) amplitudes was insensitive to neutral and negative emotional contexts. Furthermore, the time‐frequency analysis showed that the framing effect on the theta power related to the FRN was also insensitive to neutral and negative emotional contexts. Our findings suggest that brain responses to framing effects on outcome evaluation in a later cognitive appraisal stage of decision making under uncertainty may depend on the emotional context, as the effects were observed only following negative feedback in the negative emotional context.
Cognitive reappraisal and need to belong predict prosociality in Mexican‐origin adolescents
Authors: Hodge Ryan T. , Guyer Amanda E. , Carlo Gustavo , Hastings Paul D. 
Published: November 2022

AbstractThis 2‐year longitudinal study examined Mexican‐origin adolescents’ need to belong and cognitive reappraisal as predictors of multiple forms of prosocial behavior (i.e., general, emotional, and public prosocial behaviors). Prosocial behaviors, which are actions intended to benefit others, are hallmarks of social proficiency in adolescence and are influenced by intrapersonal abilities and motivations that typically develop during adolescence. Yet, few studies of Mexican‐origin or other U.S. Latinx youths have examined whether such individual difference characteristics, specifically social motivation and emotion regulation skills, support prosocial behavior. In a sample of 229 Mexican‐origin youth (Mage = 17.18 years, SD = .42, 110 girls), need to belong, cognitive reappraisal, and general prosocial behaviors were assessed at ages 17 and 19. Emotional and public forms of prosociality also were assessed at age 19. Cognitive reappraisal was positively associated with concurrent general prosociality at age 17, whereas need to belong was positively associated with concurrent public prosociality at age 19. Moderation analyses revealed that general and emotional types of prosocial behaviors at age 19 were lowest for youth with both lower need to belong and less use of cognitive reappraisal at 19 years. Greater cognitive reappraisal skills and need to belong may reflect distinct motivations for engaging in varying forms of prosocial behavior in late adolescence.
Radiofrequency‐assisted subcision combined with polycaprolactone‐based dermal fillers in the management of atrophic facial acne scars: A pilot investigative study
Authors: Lotfi Elaheh , Shafie'ei Mohammad , Ahramiyanpour Najmeh 
Published: November 2022

AbstractObjectiveThe scar's appearance and psychological burden are the most esthetically challenging issues in acne vulgaris. This study investigated the effectiveness and safety profile of combined radiofrequency‐assisted subcision, which, even though effective on both Icepeak and Rolling subtypes, is only mildly effective on boxcar lesions, and polycaprolactone‐based dermal filler with collagen stimulation potency in managing atrophic postacne scars.MethodsOur quasi‐experimental single‐arm study, after the inclusion of 10 cases over the age of 18 with moderate to severe mixed atrophic facial acne scarring, was carried out in two 3‐month separate sessions, during and after the intended intervention of which the experienced lesion improvements and also adverse events were documented. Moreover, all cases were followed for 3 months after the last session, evaluating the differences in the mentioned outcomes.ResultsWe found the combined intervention to be highly effective in improving the intended outcomes, with the total number of acne lesions (p‐value < 0.001), along with the total number of Ice peak (p‐value = 0.002), Rolling (p‐value < 0.001), and boxcar (p‐value = 0.023) lesions demonstrating statistically significant changes.ConclusionRadiofrequency‐assisted subcision combined with polycaprolactone‐based dermal fillers can be an effective intervention in managing postacne scars. However, we recommend that randomized clinical trials with larger sample sizes be carried out for a more precise conclusion.