bluuebunny/crossref_metadata_2025_split huggingface dataset:
“We're the CHATS old‐heads”: Engaging with evidence‐based practice in a reentry agency
Authors: Updyke Alison , Ghose Toorjo 
Published: November 2022

AbstractPhiladelphia has one of the country's largest populations re‐entering society after incarceration. Reentry services have been critiqued for their ineffectiveness. Scholars note the lack of evidence‐based practices (EBPs) in the field, and the challenges of translating them. Through a case study of one reentry agency implementing an EBP, we examine engagement with the intervention by clients and service providers. Qualitative interviews were conducted with clients and staff (n = 35). A grounded theory using sensitizing concepts approach was used to analyze the data. Productive engagement with the intervention was facilitated by: (1) translatability of the core EBP elements so that they addressed client and staff needs, (2) accessibility to the intervention by enhancing subjective ownership and successfully navigating logistical barriers, and (3) collectivity among participants and staff that helped them address societal and structural barriers. Productive engagement with an EBP can resist carceral processes in reentry service‐provision.
A ubiquitous endocrine disruptor tributyltin induces muscle wasting and retards muscle regeneration
Authors: Chiu Hsien‐Chun , Yang Rong‐Sen , Weng Te‐I , Chiu Chen‐Yuan , Lan Kuo‐Cheng , Liu Shing‐Hwa 
Published: November 2022

AbstractBackgroundOrganotin pollutant tributyltin (TBT) is an environmental endocrine disrupting chemical and is a known obesogen and diabetogen. TBT can be detected in human following consumption of contaminated seafood or water. The decrease in muscle strength and quality has been shown to be associated with type 2 diabetes in older adults. However, the adverse effects of TBT on the muscle mass and function still remain unclear. Here, we investigated the effects and molecule mechanisms of low‐dose TBT on skeletal muscle regeneration and atrophy/wasting using the cultured skeletal muscle cell and adult mouse models.MethodsThe mouse myoblasts (C2C12) and differentiated myotubes were used to assess the in vitro effects of low‐dose tributyltin (0.01–0.5 μM). The in vivo effects of TBT at the doses of 5 and 25 μg/kg/day (n = 6/group), which were five times lower than the established no observed adverse effect level (NOAEL) and equal to NOAEL, respectively, by oral administration for 4 weeks on muscle wasting and muscle regeneration were evaluated in a mouse model with or without glycerol‐induced muscle injury/regeneration.ResultsTBT reduced myogenic differentiation in myoblasts (myotube with 6–10 nuclei: 53.9 and 35.8% control for 0.05 and 0.1 μM, respectively, n = 4, P < 0.05). TBT also decreased myotube diameter, upregulated protein expression levels of muscle‐specific ubiquitin ligases (Atrogin‐1 and MuRF1), myostatin, phosphorylated AMPKα, and phosphorylated NFκB‐p65, and downregulated protein expression levels of phosphorylated AKT and phosphorylated FoxO1 in myotubes (0.2 and 0.5 μM, n = 6, P < 0.05). Exposure of TBT in mice elevated body weight, decreased muscle mass, and induced muscular dysfunction (5 and 25 μg/kg, P > 0.05 and P < 0.05, respectively, n = 6). TBT inhibited soleus muscle regeneration in mice with glycerol‐induced muscle injury (5 and 25 μg/kg, P > 0.05 and P < 0.05, respectively, n = 6). TBT upregulated protein expression levels of Atrogin‐1, MuRF1, myostatin, and phosphorylated AMPKα and downregulated protein expression level of phosphorylated FoxO1 in the mouse soleus muscles (5 and 25 μg/kg, P > 0.05 and P < 0.05, respectively, n = 6).ConclusionsThis study demonstrates for the first time that low‐dose TBT significantly inhibits myogenic differentiation and triggers myotube atrophy in a cell model and significantly decreases muscle regeneration and muscle mass and function in a mouse model. These findings suggest that low‐dose TBT exposure may be an environmental risk factor for muscle regeneration inhibition, atrophy/wasting, and disease‐related myopathy.
Predictors of recurrence in patients without non‐inducibility of ventricular tachycardia at the end of ablation
Authors: Nakasone Kazutaka , Fukuzawa Koji , Kiuchi Kunihiko , Takami Mitsuru , Sakai Jun , Nakamura Toshihiro , Yatomi Atsusuke , Sonoda Yusuke , Takahara Hiroyuki , Yamamoto Kyoko , Suzuki Yuya , Tani Ken‐ichi , Iwai Hidehiro , Nakanishi Yusuke , Hirata Ken‐ichi 
Published: November 2022

AbstractBackgroundVentricular tachycardia (VT) non‐inducibility at the end of ablation is associated with a less likely VT recurrence. However, it is not clear whether we should use VT non‐inducibility as a routine end point of VT ablation. The aim of this study was to evaluate VT recurrence in patients in whom VT non‐inducibility was not achieved at the end of the radiofrequency (RF) ablation and the factors attributing to the VT recurrence.MethodsWe analyzed that 62 patients in whom VT non‐inducibility was not achieved at the end of the RF ablation were studied.ResultsOver 2 years, 22 (35%) of the cases had VT recurrences. A multivariate analysis showed that an LVEF ≥35% (HR: 0.19; 95% CI: 0.06–0.49; p < .01) and elimination of the clinical VT as an acute ablation efficacy (HR: 0.23; 95% CI: 0.04–0.81; p = .02) were independent predictors of fewer VT recurrences. RF ablation was associated with a 91.1% reduction in VT episodes.ConclusionEven if VT non‐inducibility was not achieved, patients with an LVEF ≥35% or in whom the clinical VT could be eliminated might be prevented from having VT recurrences. The validity of the VT non‐inducibility of any VT should be evaluated considering each patient's background and the results of the procedure.
BioOne and SPIE: A reflection on the first 3 years of the nonprofit platform partnership
Authors: Franzen Patrick , Kane Lauren , Ritchey Scott 
Published: November 2022

Key points
There is great potential for organizations to form collaborative partnerships, particularly in the nonprofit environment, which can reduce costs and aid in strategic development.
Regular and transparent communication with internal and external stakeholders is critical to the health of any partnership, especially when doing something new or novel.
Reciprocal service‐level agreements with clear expectations and ongoing evaluation ensure the collaboration keeps pace with commercial alternatives.
The SPIE‐BioOne partnership was built to scale and incorporate future collaborators to further reduce costs and bring new ideas to the user group.
Short‐term efficacy and long‐term survival of nasopharyngeal carcinoma patients with radiographically visible residual disease following observation or additional intervention: A real‐world study in China
Authors: Huang Ying‐Ying , Cao Xun , Cai Zhuo‐Chen , Zhou Jia‐Yu , Guo Xiang , Lv Xing 
Published: November 2022

AbstractBackgroundTo explore the short‐ and long‐term outcomes in patients with nasopharyngeal carcinoma (NPC) with magnetic resonance imaging (MRI)‐detected residual disease at 3 months post‐treatment who received intervention either promptly (0 month) or following observation (after an additional 3 months).MethodsA total of 272 patients with residual disease at 3 months post‐treatment (observation [observation for additional 3 months]: 122, intervention [prompt intervention]: 150) were analyzed. Univariate and multivariate analyses were performed to examine the survival. Adverse events were analyzed in all patients.ResultsPatients in the observation group had a lower 3‐year overall survival (77.1% vs. 85.2%), progression‐free survival (10.2% vs. 18.1%), and locoregional relapse‐free survival (10.2% vs. 20.6%) (all p < .05), but not distant metastasis‐free survival (83.8% vs. 78.4%, p = .189), whereas patients in the intervention group achieved higher complete remission (CR) rates (43.3% vs. 21.2%, p = .003). Patients who achieved CR after prompt intervention had a better survival rate than those who achieved observation‐CR or non‐CR (p < .001). Multivariate analyses revealed that a wait‐and‐see policy was an independent prognostic factor for impaired survival (p < .001). No significant differences of acute or late toxicities were observed between the two groups.ConclusionsPatients with NPC with MRI‐detected residual disease 3 months post‐radiotherapy should be encouraged to undergo prompt intervention rather than adopting a passive wait‐and‐see policy.
Effective Enhancement of Thermal Conductivity and Electrical Conductivity with Poly(3,4‐ethylenedioxythiophene):Poly(4‐styrenesulfonate) through Solvent Treatment
Authors: Zheng Haoting , Wu Kun , Shi Jun 
Published: November 2022

AbstractThe preparation of poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) film is proposed as a simple and industrialized approach. PEDOT:PSS is diluted with deionized water, tetrahydrofuran, dimethyl formamide, and dimethyl sulfoxide before being dry and suction filtered to create a membrane. After treatment with polar organic solvent, the in‐plane thermal conductivity of sample is increased from 1.386 to 2.375 Wm−1 K−1. The electrical conductivity increases from 1.8 to 592 S cm−1. The structural modifications of PEDOT:PSS considerably increase the heat conductivity, according to UV, X‐ray photoelectron spectroscopy (XPS), X‐ray diffraction (XRD), and atomic force microscopy (AFM) characterization. This modification improves the polymer's thermal conductivity by increasing the contact force between molecules and changing the long chain conformation of polymers.
A Superhydrophobic Trifluoromethyl‐Containing Covalent Organic Framework Membrane for Efficient Oil/Water Separation
Authors: Chu Jia‐Qi , Lu Ya , Gan Shi‐Xian , Qi Qiao‐Yan , Jia Chao , Yao Jin , Zhao Xin 
Published: November 2022

AbstractOily water caused in the process of industry leads to not only the waste of resources, but also environmental pollution. Membrane separation, as a facile and efficient separation technology, has attracted widespread attention in the field of oil/water separation. The development of membrane materials with high separation performance is one of the key elements to improve separation efficiency. In this work, a superhydrophobic membrane composited with a trifluoromethyl‐containing covalent organic framework (COF) is prepared, which exhibits excellent performance on separations of oil/water mixtures and water‐in‐oil emulsions. For different composition of oil/water mixtures, the highest flux of oil is up to 32 000 L m−2 h−1 and oil/water separation efficiency is above 99%. Moreover, the high oil/water separation efficiency remains unchanged after successive cycles. This work provides a feasible scheme for the design of high‐efficiency oil/water separation membranes.
Life Cycle Model Reveals Sensitive Life Stages and Evaluates Recovery Options for a Dwindling Pacific Salmon Population
Authors: Kendall Neala W. , Unrein Julia , Volk Carol , Beauchamp David A. , Fresh Kurt L. , Quinn Thomas P. 
Published: November 2022

Abstract
Population models, using empirical survival rate estimates for different life stages, can help managers explore whether various management options could stabilize a declining population or restore it to former levels of abundance. Here we used two decades of data on five life stages of the population of Sockeye Salmon Oncorhynchus nerka in the Cedar River to create and parameterize a life cycle model. This formerly large but unproductive population is now in steep decline despite hatchery enhancement. We gathered population-specific data on survival during five stages: (1) egg to fry, (2) fry to presmolt, (3) presmolt to adult return from the ocean, (4) adult en route from the ocean to the spawning grounds, and (5) reproduction. We ground-truthed the model to ensure its fit to the data, and then we modified survival and other parameters during various stages to examine future scenarios. Our analyses revealed that low survival of juveniles in Lake Washington (stage 2: averaging only 3% over the past 20 years), survival of adults returning to freshwater to spawn (stage 4), and survival of adults on spawning grounds to reproduce (stage 5) are likely limiting factors. Combined increases in these stages and others (specifically, the proportion of fish taken into the hatchery to be spawned) might also recover the population. As in other integrated hatchery populations, managers must weigh options relating to balancing the fraction of natural- and hatchery-origin fish, and our results showed that increasing the fraction of fish taken into the hatchery alone will not recover the population. Our model brings together population-specific data to help managers weigh conservation strategies and understand which stages and habitats are most limiting and how much survival must increase to achieve recovery targets. By extension, our analyses also reveal the utility of such models in other cases where stage-specific data are available.
Mg/Zn metal‐air primary batteries using silk fibroin‐ionic liquid polymer electrolytes
Authors: Haskew Mathew J. , Nikman Shahin , O'Sullivan Carys E. , Galeb Hanaa A. , Halcovitch Nathan R. , Hardy John G. , Murphy Samuel T. 
Published: November 2022

AbstractBatteries are utilized in a multitude of devices encountered in our daily lives. Here we describe a comparative study of Magnesium‐air and Zinc‐air primary batteries using silk fibroin‐ionic liquid polymer electrolytes (composed of Bombyx mori silk fibroin and choline nitrate). The ionic conductivity of the films was of the order of mS cm−1 which is sufficient to satisfy the conductivity requirements for many battery applications, the open circuit voltages (V) for the Mg 1:1 SF:IL and 1:3 SF:IL batteries just after fabrication were ca. 1.8 and 1.7 V, respectively; the 1:1 SF:IL battery had a capacity of 0.84 mAh cm−2, whereas the 1:3 SF:IL battery had a capacity of 0.68 mAh cm−2. The open circuit voltages (V) for the Zn 1:1 SF:IL and 1:3 SF:IL batteries were in the range of 1.3 and 1.2 V just after fabrication; the 1:3 SF:IL battery displayed a capacity of 0.96 mAh cm−2 and the 1:3 SF:IL battery displayed a capacity of 0.72 mAh cm−2. Integration of the PE and substitution of the carbon cloth electrodes with degradable materials would offer routes to production of transient primary batteries helping to address the global issue of electronic waste (e‐waste).
Event‐triggering‐based robust optimal control for post‐stall pitching maneuver of aircraft
Authors: Shen Yaohua , Chen Mou 
Published: November 2022

AbstractIn this paper, the problem of the post‐stall pitching maneuver of aircraft with lower deflection frequency of control actuator is studied by considering the unsteady aerodynamic disturbances (UADs). A nonlinear disturbance observer is employed to estimate the UADs in order to suppress their adverse effects. And the nonzero equilibrium adaptive dynamic programming (NEADP) control method derived from the reinforcement learning is adopted to achieve the optimal control of aircraft. Simultaneously, a critic neural network is constructed to approximate the value function in the Hamilton‐Jacobi‐Bellman equation so as to realize adaptivity. Furthermore, the event‐triggering (ET) scheme with an improved triggering condition is applied in the control method in order to decrease the deflection frequency of control actuator. In addition, the Lyapunov stability analysis method is used to prove that all signals in the closed‐loop control system are uniformly ultimately bounded. And the proof by contradiction is applied to confirm that the Zeno behavior is excluded with the analysis of the minimum dwell time. Finally, simulation results verify the effectiveness of the improved ET‐based NEADP control method.
Correlation on synthesis design and surface modification towards properties and applications of carbon nanofibers and carbon nanofibers based nanocomposites
Authors: Gul Ayesha , Ghaffari Khaligh Nader , Nordin Nurdiana , Ma'amor Azman , Muhd Julkapli Nurhidayatullaili 
Published: November 2022

AbstractWith the recent advancement in nanoscience and nanotechnology, carbon nanomaterials have achieved great attention owing to their unique physico‐chemical, mechanical, thermal, and electrical properties. Amongst carbon nanomaterials, carbon nanofibers (CNF) depict a high surface‐to‐volume ratio, enhanced porosity, high mechanical strength, and low weight (light). Carbon nanofibers‐based nanocomposites (CNFN) have been developed for diverse applications. This review illustrates the recent progress in (a) the CNF synthesis via chemical vapor deposition (CVD) or electrospinning, (b) their functionalization with metals and metal oxides nanoparticles, polymers, alloys, and (c) their applications in environmental, industrial, and biomedical domains. Moreover, this study will be helpful for readers to understand CNF production, including the latest trends and fabrication techniques to obtain efficient, cost‐effective, eco‐friendly CNFN, having enhanced surface area with maximum selectivity, reproducibility, and multi‐potential applications.
Tea‐polyphenols mediated interfacial modifier to integrate reinforcement, reprocessability, and shape memory properties into rubber/carbon black composites via coordination bonds
Authors: Zhang Jihua , Qin Junhong , Wu Nan , Feng Huadong , Wang Hao , Zao Weitao , Yang Yuan , Liang Zi , Zhang Hui 
Published: November 2022

AbstractCarbon blacks are important fillers to reinforce, functionalize rubber materials and reduce their prices. However, environment‐friendly surface modification of carbon blacks is not trivial to conduct, yet challenging to effectively sever broad rubber galleries. Inspired by wet adhesion of mussel, tea polyphenols (TPs) are coated on carbon blacks by vacuum absorption method (i.e., TP@C) and then they are mixed into nitrile butadiene rubber with ZnCl2. Specially, Zn2+/TP@C coordination interfaces are formed together with crosslinking structures of Zn2+‐CN of NBR after hot pressing. As a sequence, the rubber composites achieve superior strength and modulus reinforcement owing to strong interface interactions and good dispersion of TP@Cs. Reversible coordination crosslinking network and TP@C network topology can be rearranged at elevated temperatures, endowing the composite good plasticity and reprocessablity. Furthermore, the composites possess stable shape memory properties for five cycles and good plasticity based shape memory ability, showing great advantages in application potential of smart material fields.
Assembling properties of 3,6‐dinitropyrazolo‐[4,3‐c]pyrazole‐based energetic compounds
Authors: Xinghui Jin , Fang Yuan , Yun Shen , Yufan Liu , Shengnan Yao , Shaochuan Bai , Bingcheng Hu 
Published: November 2022

AbstractIn pursuit of energetic materials with equal detonation properties and sensitivities compared to those of HMX and RDX, a series of 3,6‐dinitropyrazolo‐[4,3‐c]pyrazole‐based energetic compounds were designed, and density functional theory method was carried out to investigate the frontier molecular orbital, heats of formation, energetic properties, and impact sensitivities of the designed compounds. The results show that all the designed compounds possess high positive heats of formation range from 618.8 (A4) to 1934.3 kJ mol−1 (E2) and the –N3 energetic group was the most effective unit to improve the values of heats of formation. Values of oxygen balance of compounds E8 and F8 were zero and possess the most ideal oxygen balance. The calculated detonation properties indicate that the –C (NO2)3 group was the most useful group to enhance the densities, detonation velocities, and detonation pressures. Nearly half of the designed compounds possess higher values of h50 than RDX or HMX, which indicates that these compounds will be more stable than RDX and HMX. Based on detonation properties and impact sensitivities, five compounds (D3, D5, E5, F3, and F5) were screened as candidate compounds for high energy density materials. Finally, the distribution of the highest occupied molecular orbitals, the lowest unoccupied molecular orbitals, and electrostatic potential of the screened compounds were simulated to give an evident view on their physicochemical properties.
Alfaxalone population pharmacokinetics in the rat: Model application for pharmacokinetic and pharmacodynamic design in inbred and outbred strains and sexes
Authors: White Kate , Aldurdunji Mohammed , Harris John , Ortori Catherine , Paine Stuart 
Published: November 2022

AbstractThe translation of new injectable anesthetic drugs from rodent to humans remains slow, despite the realization that reliance on the volatile agents is unsustainable from an environmental perspective. The aim of this study was to investigate the influence of rat sex and strain on the PK and PD of the anesthetic neurosteroid alfaxalone. Forty rats had cannulas inserted under isoflurane anesthesia for drug administration and sampling. Carotid artery blood samples were collected for blood gas analysis, hematology, biochemistry, and plasma concentrations of alfaxalone. Plasma samples were assayed using liquid chromatography‐mass spectrometry. Compartmental non‐linear mixed effects methods (NLME) models were applied to two rat populations to determine whether body weight, sex, and strain influenced PK parameters. There were significant differences between the sexes for plasma clearance, half‐life and mean residence time in Lewis rats, and mean arterial blood pressure was significantly lower in the female rats at 120 min. An initial NLME PK population model was used to design an adjusted alfaxalone infusion for SD females matching plasma concentrations in males and minimizing cardiopulmonary depression but maintaining an appropriate hypnotic effect. A final NLME population model showed that alfaxalone clearance was dependent on both bodyweight and sex, whereas volume of distribution was influenced by strain. NLME PK models offer the advantage of having a single model that describes a population and therefore shares data interpretation between animals unlike the standard deterministic PK approach. This approach can be used to propose bespoke dosing regimens for optimal use of alfaxalone
Resistant starch from black rice, Oryza sativaL. var. ameliorates renal inflammation, fibrosis and injury in insulin resistant rats
Authors: Thongnak Laongdao , Jaruan Onanong , Pengrattanachot Nattavadee , Promsan Sasivimon , Phengpol Nichakorn , Sutthasupha Prempree , Jaikumkao Krit , Sriyotai Woraprapa , Mahatheeranont Sugunya , Lungkaphin Anusorn 
Published: November 2022

AbstractIt has recently been reported that black rice (BR) extract has anti‐obesity, anti‐diabetic, and anti‐osteoporosis effects. It has been shown to reduce obese‐related kidney dysfunction in animal models. This study aimed to investigate the effect of resistant starch from BR (RS) on renal inflammation, oxidative stress, and apoptosis in obese insulin resistant rats. Male Wistar rats were divided into six groups: normal diet (ND), ND treated with 150 mg of RS (NDRS150), high‐fat (HF) diet, HF treated with 100 and 150 mg of RS (HFRS100), (HFRS150), and HF treated with metformin as a positive control. Insulin resistance was shown in the HF rats by glucose intolerance, increased insulin, total area under the curve of glucose and homeostasis model assessment of insulin resistance and dyslipidemia. The resulting metabolic disturbance in the HF rats caused renal inflammation, fibrosis and apoptosis progressing to kidney injury and dysfunction. Prebiotic RS including anthocyanin from BR at doses of 100 and 150 mg ameliorated insulin resistance, dyslipidemia and liver injury. Treatment with RS reduced TGF‐β fibrotic and apoptotic pathways by inhibition of NF‐κB and inflammatory cytokines which potentially restore kidney damage and dysfunction. In conclusion, prebiotic RS from BR ameliorated obesity induced renal injury and dysfunction by attenuating inflammatory, fibrotic, and apoptotic pathways in insulin resistant rats induced by HF.