bluuebunny/crossref_metadata_2025_split huggingface dataset:
XYO3 (X = K, Na; Y = Nb, Ta) based superlattices for photocatalysis
Authors: Wang Guang‐Zhao , Chen Xiao‐Rui , Yuan Hong‐Kuan , Kuang An‐Long , Chen Hong 
Published: April 2022

The photocatalytic activities of XYO3 (X = K, Na; Y = Ta, Nb) and XYO3/X1Y1O3 (X, X1 = K, Na; Y, Y1 = Ta, Nb) systems are investigated by using hybrid density functional. All the XYO3 and XYO3/X1Y1O3 systems are indirect band gap semiconductors, and the band gap of KNbO3/KTaO3 is smaller than those of KNbO3 and KTaO3, while the band gaps of KNbO3/NaNbO3, KNbO3/NaTaO3, KTaO3/NaNbO3, KTaO3/NaTaO3, and NaNbO3/NaTaO3 are respectively between the band gaps of these two crystals which make up these superlattices. The electronic structure of KNbO3/NaTaO3 is the same as that of KTaO3/NaNbO3 since both have the same component and similar crystal structure. The band edges of all the considered superlattices are thermodynamically allowed for the water reduction and oxidation processes, and therefore, they could be used for photocatalytic water splitting.Band structures for (i) KNbO3/KTaO3, (ii) KNbO3/NaNbO3, (iii) KNbO3/NaTaO3, (iv) KTaO3/NaNbO3, (v) KTaO3/NaTaO3, and (vi) NaNbO3/NaTaO3 superlattices. The horizontal dashed lines represent the Fermi levels.
Effects of crocin supplementation on inflammatory markers, lipid profiles, insulin and cardioprotective indices in women with PCOS: A randomized, double‐blind, placebo‐controlled trial
Authors: Rahimi Giti , Shams Saeideh , Aslani Mohammad Reza 
Published: April 2022

AbstractPolycystic ovary syndrome (PCOS) is a multifactorial reproductive condition common in women of reproductive age. Hyperlipidemia, insulin resistance, obesity, and chronic low‐grade inflammation are associated with PCOS. In a clinical trial study, women with PCOS were divided into two groups (n = 25 each): the intervention group receiving crocin (15 mg, twice daily) and the control group receiving a placebo. The duration of intervention in both groups was 12 weeks. Pre‐ and postintervention, demographic information, lipid profile, fasting blood glucose (FBG), fasting insulin, and inflammatory markers (interleukin‐6 [IL‐6] and tumor necrosis factor‐alpha [TNF‐α]) were measured. Intervention with crocin significantly increased the mean high‐density lipoprotein cholesterol postintervention compared to the placebo group, while exerting a suppressive effect on the increase in mean low‐density lipoprotein cholesterol, triglycerides, and cholesterol levels. Intervention with crocin also exerted inhibitory effects on changes in FBG and insulin, so that crocin improved insulin and cardioprotective indices. Finally, despite the increased inflammatory markers (IL‐6 and TNF‐α) in the placebo group, crocin treatment had protective effects on their increased changes. Thus, crocin supplementation could be considered in the therapeutic targets of women with PCOS.
Two‐phase multivariate supplier selection for symmetric specification region and correlated quality characteristics
Authors: Chatterjee Moutushi 
Published: April 2022

AbstractAmong different yardsticks of assessing a supplier's performance and comparing the same with other competing suppliers, quality is often considered as one of the most important criteria. The problem becomes even more complicated for multivariate processes having more than one correlated quality characteristics. Unfortunately, very few research work has been carried out in literature, to compare performances of two suppliers having multivariate processes with correlated quality characteristics and symmetric specification region. In the present article, a two‐phase hypothesis testing‐based supplier selection process using multivariate process capability indices (MPCIs) called and is proposed to address this issue. While measures potential capability of a multivariate process, measures its actual capability. The proposed method is easy to implement in practice and hence is suitable for practical applications. A real‐life example and a simulated example are discussed to supplement the theory developed in this article.
Using EMG signals to assess proximity of instruments to nerve roots during robot‐assisted spinal surgery
Authors: Li Qianqian , Gu Guanghui , Wang Liang , Song Rui , Qi Lei 
Published: April 2022

AbstractBackgroundDetecting neural threats using electromyography (EMG) has gained recognition in the field of spinal surgery. To provide an efficient approach to detect neural threats during the operation of the spinal surgery robot, an automated method based the internal connection between EMG signal and neural proximity (NP) was explored by experiments.MethodsA NP classifier was designed to distinguish the pattern of the threats. Then, it was evaluated in rabbit models in vivo. The experiments were conducted using 20 rabbits. In each rabbit, two puncture paths were created using a surgical robot. For each path, EMG signals were recorded at series of path‐points with different neural proximities, and were constructed as datasets after data cleaning and processing. The proposed NP classifier was trained and tested on the datasets.ResultsClassification accuracy of Path 1 and Path 2 were 99.1% and 94.0%, respectively.ConclusionThis feasibility study proved that EMG can be used to detect the proximity of surgical instruments to nerve roots during robot‐assisted spinal surgery. As the methods of detecting neural threats for surgical robots are still scarce, we believe this work will improve the clinical performance of spinal surgery robots and help the doctors to perform surgery safely.
Flexible robotic transanal resection of rectal polyps – A case series
Authors: Fok Kar Yin , Arabaci Ferhat , Barto Walid 
Published: April 2022

AbstractBackgroundFlexible systems in robotic transanal surgery (RTA) are a proposed solution to the challenges of transanal minimally invasive surgery (TAMIS). RTA was performed with the Medrobotics Flex® Robotics System to determine its safety and feasibility.MethodsMedrobotics Flex® Robotics System was used for transanal resection of benign rectal polyps by a single surgeon in a tertiary centre, and cases retrospectively reviewed.ResultsFive patients underwent flexible RTA, average age was 67 years. Polyps were between 5 and 12 o'clock, mean distance of 8.3 cm from the anal verge. Average operating time was 143 min. There was no peri‐operative or 30‐day morbidity or mortality. Histopathology included tubulovillous adenoma (TVA), and one hyperplastic polyp, all were clear of the surgical margin.ConclusionThis is the first case series using Medrobotics Flex® Robotics System for RTA in a tertiary Australian public hospital. Flexible RTA is safe and feasible for the resection of benign rectal polyps.
Electrical resistivity measurements to determine the steel fiber content of concrete
Authors: Cleven Simon , Raupach Michael , Matschei Thomas 
Published: April 2022

AbstractAlthough steel fiber reinforced concrete is becoming increasingly popular in the construction industry, its application is currently limited to certain areas. One reason is the lack of an economical non‐destructive testing method to determine the content, distribution, and orientation of steel fibers in fresh and hardened concrete. However, these parameters are decisive for the assessment of the static performance of a building component. In this article a new test method is proposed, which is based on the electrical conductivity of concrete. Using a two‐electrode experimental set‐up, measurements of the electrical conductivity were done on hardened concrete cubes with defined fiber content and a correlation between electrical conductivity and fiber content could be identified. Within the scope of extensive test series, the fiber content and the age of specimens were varied, and several identical series were produced and observed to ensure statistically verified results. At this stage of research the test method based on electrical conductivity measurement provides reliable results on the fiber content of preconditioned concrete cubes. Based on the results a new model was developed to quantify the fiber content of the examined cubes. This model is based on the estimation of the relative conductivity, the so‐called increase of conductivity. Undesired influences caused by aging, respectively hydration in the young concrete age were eliminated, by relating the conductivity of fiber reinforced concrete to an unreinforced concrete. Further investigations with focus on the influence of concrete composition and other specimen sizes are going to be conducted as next steps for the development of an in situ test setup for the diagnosis of concrete structures.
Embryonic exposure to butylparaben and propylparaben induced developmental toxicity and triggered anxiety‐like neurobehavioral response associated with oxidative stress and apoptosis in the head of zebrafish larvae
Authors: Lite Christy , Guru Ajay , Juliet Melita , Arockiaraj Jesu 
Published: April 2022

AbstractParabens are synthetic antimicrobial compounds used as a preservative for extending the shelf life of food, pharmaceutical and cosmetic products. The alkyl chain length of the paraben esters positively correlates with their antimicrobial property. Hence, long‐chain paraben esters, namely butylparaben and propylparaben, are used in combination as they have better solubility and antimicrobial efficacy. Extensive use of parabens has now resulted in the ubiquitous presence of these compounds in various human and environmental matrices. During early life, exposure to environmental contaminants is known to cause oxidative‐stress mediated apoptosis in developing organs. The brain being one of the high oxygen‐consuming, metabolically active and lipid‐rich organ, it is primarily susceptible to reactive oxygen species (ROS) and lipid peroxidation (LP) induced neuronal cell death. The primary cause for the impairment in cognitive and emotional neurobehvioural outcomes in neurodegenerative disease was found to be associated with neuronal apoptosis. The present study aimed to study butylparaben and propylparaben's effect on zebrafish during early embryonic stages. Besides this, the association between alteration in anxiety‐like neurobehavioral response with oxidative stress and antioxidant status in head region was also studied. The study results showed variation in the toxic signature left by butylparaben and propylparaben on developmental parameters such as hatching rate, survival and non‐lethal malformations in a time‐dependent manner. Data from the light–dark preference test showed embryonic exposure to butylparaben and propylparaben to trigger anxiety‐like behavior in zebrafish larvae. In addition, a significant increase in intracellular ROS and LP levels correlated with suppressed antioxidant enzymes: superoxide dismutases (SOD), catalases (CAT), Glutathione peroxidase (GPx), glutathione S‐transferase (GST), and Glutathione (GSH) activity in the head region of the zebrafish larvae. Acetylcholinesterase (AChE) activity was also suppressed in the exposed groups, along with increased nitric oxide production. The overall observations show increased oxidative stress indices correlating with upregulated expression of apoptotic cells in a dose‐dependent manner. Collectively, our findings reveal butylparaben and propylparaben as an anxiogenic neuroactive compound capable of inducing anxiety‐like behavior through a mechanism involving oxidative‐stress‐induced apoptosis in the head of zebrafish larvae, which suggests a potential hazard to the early life of zebrafish and this can be extrapolated to human health as well.
Ultrasonographic, gastroscopic and histologic report of a mass‐like lesion in the stomach of a dog: Chronic lymphoplasmacytic and hyperplastic gastritis
Authors: Bruining‐Staal Karin , Verburgh‐Hoffmann Gaby , Ploeg Margreet 
Published: April 2022

AbstractA 7‐year‐old Boomer dog was presented with chronic vomiting over the past 6 months. Ultrasonography showed a severely thickened gastric wall with the aspect of a nodular mass. Gastroscopy confirmed a nodular mass. Histopathology of gastroscopically taken biopsies revealed chronic lymphoplasmacytic gastritis. The mass‐like lesion was surgically resected and full‐thickness histopathology confirmed chronic hyperplastic gastritis. The mucous cells of the foveolae were proliferated. The dog recovered after chronic lymphoplasmacytic and hyperplastic gastritis treatment. Chronic lymphoplasmacytic and hyperplastic gastritis should be included as a differential diagnosis for gastric nodular masses.
Verhütung in der deutschsprachigen Wikipedia: Eine Inhalts- und Qualitätsanalyse
Authors: Döring Nicola , Lehmann Stephan , Schumann-Doermer Claudia 
Published: April 2022

Zusammenfassung
Hintergrund
Jugendliche und Erwachsene beziehen Informationen über Verhütung heute oft per Internet, vor allem über die Online-Enzyklopädie Wikipedia, da Google-Suchen meist Wikipedia-Einträge als Toptreffer liefern.

Ziel der Arbeit
Vor diesem Hintergrund ist es Ziel des vorliegenden Beitrags, erstmals Inhalte und Qualität von Wikipedia-Artikeln über Verhütungsmethoden systematisch zu analysieren. Geprüft werden dabei 5 zentrale Qualitätsdimensionen: die Ausprägung der Korrektheit (Forschungsfrage F1), der Vollständigkeit (F2), der Neutralität (F3), der Verständlichkeit (F4) und der Aktualität (F5) der Verhütungsinformationen sowie auf dieser Basis auch ihre Gesamtqualität (F6).

Material und Methoden
Es wurde eine Stichprobe aller deutschsprachigen Wikipedia-Artikel zu allen Verhütungsmethoden gebildet (N = 25). Diese Artikel wurden mittels eines auf der Basis des Forschungsstandes entwickelten und reliabilitätsgeprüften Codebuchs von 3 unabhängigen, geschulten Codierenden analysiert. Die Datenanalyse erfolgte mit SPSS. Die Studie ist präregistriert und alle Daten, Materialien und Analyseskripte sind öffentlich verfügbar.

Ergebnisse
Es zeigte sich, dass die 25 Wikipedia-Artikel zu Verhütungsmethoden in ihrer inhaltlichen Qualität stark variierten. Während sie hinsichtlich Korrektheit (F1) und Neutralität (F3) im Mittel gute Qualität aufwiesen, erreichten sie hinsichtlich Vollständigkeit (F2), Verständlichkeit (F4) und Aktualität (F5) nur mittelmäßige Werte, woraus sich dann auch eine moderate Gesamtqualität ergab (F6).

Diskussion
Weitere Forschung sowie Praxismaßnahmen sind notwendig, um die Qualität von Verhütungsinformationen in der Wikipedia und in anderen sozialen Medien noch besser einschätzen und zielgerichteter verbessern zu können.
ASK1 is a novel molecular target for preventing aminoglycoside-induced hair cell death
Authors: Ogier Jacqueline M. , Gao Yujing , Dunne Eileen M. , Wilson Michael A. , Ranganathan Sarath C. , Tesch Gregory H. , Nikolic Paterson David J. , Dabdoub Alain , Burt Rachel A. , Nayagam Bryony A. , Lockhart Paul J. 
Published: April 2022

Abstract
Aminoglycoside antibiotics are lifesaving medicines, crucial for the treatment of chronic or drug resistant infections. However, aminoglycosides are toxic to the sensory hair cells in the inner ear. As a result, aminoglycoside-treated individuals can develop permanent hearing loss and vestibular impairment. There is considerable evidence that reactive oxygen species (ROS) production and the subsequent phosphorylation of c-Jun N-terminal kinase (JNK) and P38 mitogen-activated protein kinase (P38) drives apoptosis in aminoglycoside-treated hair cells. However, treatment strategies that directly inhibit ROS, JNK, or P38 are limited by the importance of these molecules for normal cellular function. Alternatively, the upstream regulator apoptosis signal-regulating kinase 1 (ASK1/MAP3K5) is a key mediator of ROS-induced JNK and P38 activation under pathologic but not homeostatic conditions. We investigated ASK1 as a mediator of drug-induced hair cell death using cochlear explants from Ask1 knockout mice, demonstrating that Ask1 deficiency attenuates neomycin-induced hair cell death. We then evaluated pharmacological inhibition of ASK1 with GS-444217 as a potential otoprotective therapy. GS-444217 significantly attenuated hair cell death in neomycin-treated explants but did not impact aminoglycoside efficacy against P. aeruginosa in the broth dilution test. Overall, we provide significant pre-clinical evidence that ASK1 inhibition represents a novel strategy for preventing aminoglycoside ototoxicity.

Key messages

ASK1 is an upstream, redox-sensitive regulator of P38 and JNK, which are known mediators of hair cell death.

Ask1 knockout does not affect hair cell development in vivo, but significantly reduces aminoglycoside-induced hair cell death in vitro.

A small-molecule inhibitor of ASK1 attenuates neomycin-induced hair cell death, and does not impact antibiotic efficacy in vitro.

ASK1 may be a novel molecular target for preventing aminoglycoside-induced hearing loss.
Interdigitation-Induced Order and Disorder in Asymmetric Membranes
Authors: Frewein Moritz P. K. , Piller Paulina , Semeraro Enrico F. , Batchu Krishna C. , Heberle Frederick A. , Scott Haden L. , Gerelli Yuri , Porcar Lionel , Pabst Georg 
Published: April 2022

AbstractWe studied the transleaflet coupling of compositionally asymmetric liposomes in the fluid phase. The vesicles were produced by cyclodextrin-mediated lipid exchange and contained dipalmitoyl phosphatidylcholine (DPPC) in the inner leaflet and different mixed-chain phosphatidylcholines (PCs) as well as milk sphingomyelin (MSM) in the outer leaflet. In order to jointly analyze the obtained small-angle neutron and X-ray scattering data, we adapted existing models of trans-bilayer structures to measure the overlap of the hydrocarbon chain termini by exploiting the contrast of the terminal methyl ends in X-ray scattering. In all studied systems, the bilayer-asymmetry has large effects on the lipid packing density. Fully saturated mixed-chain PCs interdigitate into the DPPC-containing leaflet and evoke disorder in one or both leaflets. The long saturated acyl chains of MSM penetrate even deeper into the opposing leaflet, which in turn has an ordering effect on the whole bilayer. These results are qualitatively understood in terms of a balance of entropic repulsion of fluctuating hydrocarbon chain termini and van der Waals forces, which is modulated by the interdigitation depth. Monounsaturated PCs in the outer leaflet also induce disorder in DPPC despite vestigial or even absent interdigitation. Instead, the transleaflet coupling appears to emerge here from a matching of the inner leaflet lipids to the larger lateral lipid area of the outer leaflet lipids.
Graphical abstract
Film. Geography: stirring still remains
Authors: Doel Marcus A. 
Published: April 2022

AbstractInspired by the distinction that Gilles Deleuze drew between the ‘movement-image’ and the ‘time-image,’ the paper considers the ‘film’—the ‘skin’—of ‘film geography,’ not in terms of the customary geography of film, the geography in film, or the geography from film, but rather in terms of geography as film, a literal ‘film’ geography or ‘filmic’ geography. To get under the skin of film geography, the paper proceeds in three parts. The first part shatters the conception of film as a re-presentation. The second touches a raw nerve by channelling the power of the false. The third splits open and unfolds the two faces of film, namely the ‘movement-image’ and the ‘time-image.’ By way of conclusion, the paper ends its flaying of film geography with a ‘stirring still’ taken from Michael Madsen’s (2010) Into Eternity: A Film for the Future, which documents the construction of Onkalo, the world’s first deep-geological nuclear-waste disposal facility that must remain undisturbed for at least 100,000 years once the tomb is sealed in the early twenty-second century.
Learning Dynamics by Reservoir Computing (In Memory of Prof. Pavol Brunovský)
Authors: Hara Masato , Kokubu Hiroshi 
Published: April 2022

AbstractWe study reservoir computing, a machine learning method, from the viewpoint of learning dynamics. We present numerical results of learning the dynamics of the logistic map, one of the typical examples of chaotic dynamical systems, using a 30-node reservoir and a three-node reservoir. When the learning is successful, an attractor that is smoothly conjugate to the logistic map to be learned is observed in the phase space of the reservoir. Inspired by this numerical result, we introduce a degenerate reservoir system and use it to mathematically confirm this observation. We also show that reservoir computing can learn information about dynamics not included in the training data, which we believe is a remarkable feature of reservoir computing compared to other machine learning methods. We discuss this feature in connection with the above observation that there is a smooth conjugacy between the attractor in the reservoir and the dynamics to be learned.
Genetic variability, combining ability and molecular diversity-based parental line selection for heterosis breeding in field corn (Zea mays L.)
Authors: Mukri Ganapati , Patil Meghashri S , Motagi Babu N , Bhat Jayant S , Singh Chandu , Jeevan Kumar S. P. , Gadag R. N , Gupta Navin C , Simal-Gandara Jesus 
Published: April 2022

Abstract
Background
The demand of maize crop is increasing day by day, hence to reduce the production and demand gap, there is a need to extract the high yielding parental lines to improve per se yield of the hybrids, which could help to enhance the productivity in maize crops.

Methods and results
The present investigation was carried out to select the best medium maturing inbred lines, among a set of 118 inbred lines. Based on the Duncan multiple range test, out of 118 lines, 16 inbred lines were selected on the basis of its high yield per se and flowering time. The molecular diversity was carried out using SSR markers linked to heterotic QTL and up on diversity analysis it classified selected genotypes in to three distinct groups. Among the selected inbred lines, a wider genetic variability and molecular diversity were observed. A total of 39 test crosses were generated after classifying 16 inbred lines in to three testers and thirteen lines (based on per se grain yield and molecular diversity) and crossing them in line × tester manner.

Conclusion
Combining ability analysis of these parental lines showed that female parents, PML 109, PML 110, PML 111, PML 114 and PML 116 showed additive effect for KRN and grain yield, whereas male parents, PML 46, and PML 93 showed epistatic effect for KRN and PML 102 showed epistatic effect for grain yield. The generated information in the present investigation may be exploited for heterosis breeding in filed corn.

Key messages
To tackle the balanced dietary requirement of Indian population; we focused to enhance the productivity of maize hybrids using genetically broad based, elite, diverse inbred lines. Combination of selection criterion, not only augment the productivity but also improves the quality of hybrid/s.
Expert system design for vacant parking space location using automatic learning and artificial vision
Authors: Carrera García Juan Manuel , Recas Piorno Joaquín , Guijarro Mata-García María 
Published: April 2022

AbstractFinding a free parking space nowadays is a recurring problem in increasingly crowded public parking lots. The present study offers a solution that is based on the analysis of zenith images using artificial vision and is capable of automatically analyzing both the available spaces in the parking lot and their real-time occupancy. In an initial phase, the presented system semi-automatically detects the available parking spaces by filtering, thresholding, and carrying out a process of extracting the contour and approximating to a polygon the parking spaces of an empty parking lot. Once the size and location of the parking spaces have been mapped, the system is capable of detecting not only the presence of a vehicle in a parking space, but also the area of the parking space occupied by it with an accuracy of 98.21% using Region-based Convolutional Neural Networks. This feature allows the system to specify the appropriate parking space for a new vehicle entering the parking lot based on its specific dimensions and the correct location of the cars parked in the spaces adjacent to the free space.