bluuebunny/crossref_metadata_2025_split huggingface dataset:
Co-designing a film showcasing the dental experiences of community returners (ex-offenders)
Authors: Booth Joelle , McMullen Heather , Rodriguez Andrea , Muirhead Vanessa 
Published: January 2025

BackgroundThe oral health of over 90,000 individuals in UK prisons is four times worse than the general population. A recent scoping review on the oral health of prisoners inside the justice system highlighted the lack of research about what happens when they transition out of prison to become community returners.ObjectivesTo co-design a film to showcase the dental experiences of community returners before and after they transition out of prison, change perceptions and inform oral health research priorities.MethodsThis action research involved five community returners, recruited through third sector organisations, who attended virtual workshops. Participants in the first workshop designed the storyboard; community returners incorporated their own stories into fictional characters to portray their lived experiences. They developed the character stories and wrote the script in the second workshop. A community film production company produced the film and used professional actors who had contact with the justice system to depict the characters in the film.ResultsThe final film, titled “My Story, My Words, My Mouth” explored themes such as self-care oral health behaviours, dental care provision in prison, access to healthcare, stigmatisation, disclosure and improving oral health to support societal reintegration. The film was screened at an open event for stakeholders and included a question-and-answer session and recorded videos where viewers shared their feedback to inform future research projects.ConclusionCo-design can be an empowering platform to hear the voices of community returners. Using the medium of film an oral health promotion tool can build understanding about the oral health needs of underrepresented groups. This egalitarian and power-sharing approach can also provoke critical discussion and actively involve underrepresented people in research that impacts their lives to develop strategies, to set priorities and improve their oral health.
Effects of clear aligners treatment in growing patients: a systematic review
Authors: D’Antò Vincenzo , De Simone Vittoria , Caruso Silvia , Bucci Paolo , Valletta Rosa , Rongo Roberto , Bucci Rosaria 
Published: January 2025

IntroductionIn recent years, the use of Clear aligners (CA) has been diffused among children and adolescents. This systematic review aimed to summarize the literature regarding the effects of CA therapy in growing patients, including dentoalveolar and skeletal effects, periodontal changes, and quality of life measurements.MethodsAn electronic search on four databases was performed until September 2023, and studies including patients &lt;18 years, treated with CA were selected. Studies with less than 10 patients and in vitro/laboratory studies were excluded. Study selection, data extraction, and risk of bias assessment were independently performed by two reviewers. The “Risk of Bias 2” (RoB 2) and the “Risk of Bias in Non-randomized Studies of Interventions” (ROBINS-I) tools were applied to assess the methodological quality of the included studies. Due to the heterogeneity in methodologies and outcomes encountered in the included studies, a qualitative synthesis of the results was provided.Results and conclusionsThe search resulted in 32 papers (3 RCTs), with sample sizes ranging between 15 and 113. The overall risk of bias in the RCT was low, while the risk of bias in the non-RCT ranged between moderate and serious for most of the included studies. Dentoskeletal and periodontal effects were the most frequently reported outcomes. The most common comparison group was multibracket fixed therapy, while only 5 studies had an untreated control group. Significant changes in the transversal maxillary arch width after treatment with CA were reported in some studies. However, while dentoalveolar effects have been reported consistently, controversial findings were found regarding the changes in skeletal bases after treatment with CA. Concerning the results on the sagittal plane, the current literature does not support the effectiveness of CA with mandibular advancement features in correcting dentoskeletal Class II, compared to traditional functional orthopedic appliances. In the short-term evaluation, periodontal variables and bacterial levels seemed to be better controlled during CA therapy, compared to the fixed multibracket therapy. With regard to quality of life measurements, there are inconsistent findings to support differences between CA therapy and fixed multibracket appliances. Nevertheless, additional high-quality studies are required to formulate more reliable conclusions.Systematic Review Registrationhttps://osf.io/wmerq.
The carbon footprint and energy consumption of liver transplantation
Authors: De Simone Paolo , Lai Quirino , Ducci Juri , Campani Daniela , Biancofiore Giandomenico 
Published: January 2025

Background and aimsThere is growing interest in the environmental impact of surgical procedures, yet more information is needed specifically regarding liver transplantation. This study aims to quantify the total greenhouse gas emissions, or carbon footprint, associated with adult whole-size liver transplantation from donors after brain death, including the relevant back-table graft preparation.MethodsThe carbon footprint was calculated retrospectively using a bottom-up approach. This approach sums the volumes of energy consumption (kWh), volatile anesthetics (ml), solid waste (kg), and units of blood products transfused for each transplant. These consumption values were converted using validated conversion factors to the equivalent mass of carbon dioxide released into the environment (kg CO2e).ResultsA total of 147 patients with a mean age of 55 years (male, 78.9%) who underwent liver transplants between 2021 and 2022 were analyzed, resulting in 45.5 tons CO2e. The mean (SD) carbon footprint for each procedure was 309.8 (33.2) kg CO2e [95% CI: 304.4; 315.3]. Total energy power consumption was 96.5 MW, contributing 65.4% of greenhouse emissions (29.8 tons CO2e), while volatile anesthetics, solid waste, and blood product transfusions contributed 8.0% (3.64 tons CO2e), 5.9% (2.7 tons CO2e), and 20.6% (9.4 tons CO2e), respectively. The duration of surgery (t = 29.0; p &lt; 0.001), transfused red blood cells (t = 13.1; p &lt; 0.001), fresh frozen plasma (t = 11.1; p &lt; 0.001), platelets (t = 8.9; p &lt; 0.001), and the use of an extracorporeal pump machine (t = 3.6; p &lt; 0.001) had the greatest effects on greenhouse gas emissions.ConclusionsLiver transplantation requires significant energy and is associated with considerable greenhouse gas emissions, particularly during longer procedures. Transplant clinicians, hospital administrators, policymakers, and patients should be aware of the environmental impact of liver transplantation and collaborate to adopt sustainable energy practices.
Modified single-incision MIS-TLIF with expandable tubular assistance for degenerative lumbar spine diseases
Authors: Hu Wenlong , He Fei , Sun Kai , Wan Haiwu , Ruan Sijun , Huang Bo 
Published: January 2025

ObjectiveEvaluating the clinical value of the modified single-incision posterior median approach with expandable tubular assistance for lumbar interbody fusion in managing degenerative lumbar spine diseases.MethodA retrospective analysis was conducted on 121 patients with single-level degenerative lumbar spine disease treated in our spine surgery department from January 2017 to December 2021. Of these, 72 patients underwent a modified single-incision posterior median approach with expandable tubular assistance lumbar interbody fusion (single-incision MIS-TLIF group), while 49 patients received the classic open posterior median incision P-TLIF (open surgery group). We collected basic demographic data including age, gender, BMI, and surgical level. Surgical-related indicators such as operation time, intraoperative blood loss, postoperative drainage, length of hospital stay, hospital costs, and complication rates were compared between the two groups. Laboratory results [whole blood C-reactive protein (CRP), serum creatine kinase (CK)] and clinical outcomes [VAS scores for low back and leg pain, Oswestry Disability Index (ODI), excellent and good rate according to the modified MacNab criteria, and interbody fusion rate according to the Brantigan criteria] were also evaluated.ResultThere were no significant differences in the basic demographics between the two groups. The operation time, postoperative hospital stay, and hospital costs were also similar between the groups. However, significant differences were observed in intraoperative blood loss, postoperative drainage, and complication rates. On postoperative days 1 and 3, whole blood CRP and CK levels showed marked differences between the groups. At 3, 6, and 12 months postoperatively, the single-incision MIS-TLIF group had lower ODI scores and VAS scores for back pain compared to the open surgery group. The excellent and good rate according to the MacNab criteria was higher in the single-incision MIS-TLIF group. There were no significant differences in leg pain VAS scores and interbody fusion rates at 12 months postoperatively between the groups.ConclusionThe modified single-incision posterior median approach with expandable tubular assistance lumbar interbody fusion is highly effective in treating degenerative lumbar spine diseases. It results in less postoperative pain, faster recovery, and significant improvement in postoperative functional outcomes, making it a valuable treatment option.
The method described by Czosnyka is particularly suitable for measuring CPPe in patients undergoing cerebral angiography
Authors: Liang Yunyun , Mo Pei , Chen Yonghong , Liu Xinwu , Chen Lin , Zhou Xiaomin , Wang Zijing , Fu Junyi , Xie Longchang 
Published: January 2025

BackgroundThe primary objective of this study was to estimate the effective cerebral perfusion pressure (CPPe), critical closing pressure (CrCP), and resistance-area product (RAP) of the intravascular common carotid artery using three different methods. These estimates were then compared to the reference method of linear regression (LR).MethodsIn our previous study, we employed linear regression to evaluate the values of CrCP and RAP. To assess the consistency of results obtained from alternative assessment methods (CPPe, CrCP, and RAP) with the linear regression LR, we conducted a secondary analysis of the previously collected data. We estimated the CPPe, CrCP, and RAP of the intravascular common carotid artery using three different methods: Belford's method (mean/diastolic pressure), Czosnyka's method (systolic/diastolic pressure, CZO), and Schmidt's method (systolic/diastolic pressure, SCH), and compared these estimates with LR. CPPe is calculated as the difference between mean arterial pressure and CrCP. The primary outcome was the mean differences and biases between CPPe, CrCP, and RAP of intravascular common carotid artery, the secondary outcome was correlations and agreement among these various estimates of CPPe measurements.ResultsNineteen patients were included in this analysis. The median age was 53.5 ± 11.6 years, with 73.7% being men. There were no significant differences in CPPe, RAP and CrCP between the right common carotid artery (RCCA) and the left common carotid artery (LCCA) by using three different methods. Compared to the LR, the mean differences in CPPe and CrCP values were no significant for LCCA according to SCH, CZO and BEL method. But for RAP, the three methods are different in terms of mean differences compared with the LR. CPPe and CrCP revealed a small mean bias compared CPPCZO with CPPLR. Comparing CPPLR measurements with CPPBEL, the mean bias was higher with wider LoA. BEL and CZO showed a strong correlation with LR in Pearson correlation coefficients.ConclusionThe CPPe, CrCP, and RAP values obtained using the CZO calculation methods are comparable to those measured using the reference method. These findings may provide valuable insights for patients undergoing digital subtraction brain angiography, aiding in the determination of the most suitable approach for individualized blood pressure management.
In Vivo Effectiveness of Pleurotus ostreatus in Degradation of Toxic Metabolites of Filamentous Fungi Such as Aflatoxin B1 and Zearalenone
Authors: Zapaśnik Agnieszka , Bryła Marcin , Wojtczak Adrian , Sokołowska Barbara 
Published: January 2025

Background/Objectives: Mycotoxins, secondary metabolites synthesized by filamentous fungi, have been classified as dangerous substances and proven to be carcinogenic, as well as to have genotoxic, nephrotoxic, hepatotoxic, teratogenic, and mutagenic properties. Despite numerous trials to develop an effective and safe-for-human-health method of detoxification, there is still a high risk associated with the occurrence of these toxins in food and feed. Biological methods of food preservation are an alternative option to conventional chemical and physical methods, characterized by their less negative impact on human health as well as their high efficiency against filamentous fungi and other foodborne pathogens. Mycoremediation is a new biotechnique based on the capability of fungi to detoxify matrices from various pullulans. Ligninolytic enzymes produced by white rot fungi (WRF) characterize a high efficiency in the degradation of various mycotoxins. Methods: In our study, Pleurotus ostreatus, as a representative of WRF, was cultivated on a medium contaminated by AFB1 and ZEN (mushroom substrate and maize) in a few variants of concentration. After the cultivation, medium and fruiting bodies were collected and analyzed with the usage of HPLC and LC/MS methods. Results: The reduction oscillated between 53 and 87% (AFB1) and 73 and 97% (ZEN) depending on the initial concentration of toxins in the medium. Grown fruiting bodies contained insignificant amounts of both toxins. Conclusions: These findings confirm the potential of P. ostreatus as an effective biological agent for reducing mycotoxins in contaminated medium, highlighting its applicability in developing sustainable and safe methods for detoxification.
Suplementación de extracto de orégano (Origanum vulgare) y ácido fórmico para controlar la vibriosis en acuicultura
Authors: Criollo Nivicela Sara Anahi , Peña María José , Mocha Cuenca Brian , Sorroza Ochoa Lita 
Published: January 2025

La vibriosis es una enfermedad de origen bacteriano que afecta al cultivo de camarón ocasionando pérdidas económicas. El objetivo de este trabajo fue evaluar la sinergia entre extracto de orégano (Origanum vulgare), sales de potasio y ácido fórmico para la reducción de bacterias del género Vibrio en el cultivo de camarón. El estudio se efectuó en el laboratorio de Microbiología de la Universidad Técnica de Machala. Se probó in vitro ácido fórmico, formiato de potasio, extracto de orégano y una mezcla denominada “Oseanah” con y sin Tween 80 (T80). Se analizó el efecto inhibitorio de los tratamientos frente a cepas de Vibrio sp. totales por 24 horas mediante método Kirby-Bauer en placas con Agar Muller Hinton. Los tratamientos con y sin T80 presentaron un mayor halo de inhibición, por lo tanto, se evaluó en juveniles de camarón. Para ello se aplicó dos tratamientos y un control, por triplicado: T0: control, T1: Oseanah, T2: Oseanah + T80. Se utilizó 45 organismos de Penaeus vannamei, repartidos al azar, alimentándolos 2 veces al día. Se hizo recambios de agua al 30 %. Según los resultados del recuento en placa, el tratamiento T1 tuvo una reducción significativa (p < 0,05) con 97,67 % de la carga de Vibrio sp. mientras que el tratamiento T2 un 92,33 %. Esto indica que la aplicación de “Oseanah” fue más efectiva en reducir la carga bacteriana. Finalmente, la mezcla de aceite de orégano con diformiato de potasio demostró un efecto sinérgico inhibiendo el crecimiento de vibrios, lo que sugiere ser una opción amigable para minimizar la aplicación de antibióticos en la producción acuícola.
Rancang Bangun Sistem Monitoring Alat Non Invasive untuk Screaning Gejala Klinis Penyakit Kardiovaskular Berbasis Internet of Medical Things (IoMT )
Authors: Danang Widyawarman  , Tri Haston  , Brilian wulansari  
Published: January 2025

Proses pengukuran nilai asam urat, kolesterol dan kadar gula darah umumnya dilakukan dengan menggunakan metode invasive atau dengan melukai bagian tubuh untuk mengambil sampel darah. Pada metode invasive diperlukan 3 alat yang berbeda untuk dapat mengetahui kadar gula darah, kolestrol dan asam urat. Pada penelitian ini pengukuran dilakukan dengan menggunakan metode non-invasive atau tanpa melukai bagian tubuh dengan berbasis Internet of Medical Things (IoMT). Alat ini dilengkapi dengan Liquid Crystal Display dan aplikasi Web server sebagai penampil nilai hasil pengukuran. Penelitian ini bertujuan untuk mengukur nilai asam urat, kolesterol, kadar gula darah dan saturasi oksigen yang dilakukan dengan memanfaatkan pemancaran cahaya LED merah pada sensor yang dipasangkan pada jari. Nilai output dari sensor berupa tegangan diproses pada arduino NodeMCU ESP 32 untuk diubah menjadi bit dan dilakukan perhitungan untuk mendapatkan nilai asam urat, kolesterol, kadar gula darah, dan saturasi oksigen. Nilai yang terukur kemudian akan dikirimkan ke firebase agar dapat ditampilkan pada aplikasi Web server dan LCD yang digunakan untuk pemetaan penyakit di suatu wilayah dan membantu monitoring dokter.
ANALISIS SENTIMEN MENGGUNAKAN NBC DAN SVM UNTUK MENGETAHUI RESPON TERHADAP KINERJA PRESIDEN MELALUI MEDIA INSTAGRAM
Authors: Amir Hamzah  , Renna Yanwastika Ariyana  , Uning Lestari  
Published: January 2025

The president's performance can be revealed through the public's response to various presidential programs in the economic or industrial sector which are uploaded on the President's official Instagram media. The public's response to each uploaded post is interesting data to analyze. This research aims to conduct sentiment analysis of the public's response to the president's performance, by uploading the president's activities on Instagram using the Naive Bayes Classifier (NBC) and Support Vector Machine (SVM) methods. A total of 18,660 responses to the President's 5 Instagram posts on economic and industrial activities between March and September 2024. The data was then filtered to just 15,306 comments which were determined as a dataset. Dataset labeling before classification is carried out using the lexicon based method. The research results show that sentiment towards the president's performance is 28.3% positive, 36.8% neutral and 34.9% negative. Meanwhile, the NBC and SVM classification results obtained showed an accuracy of 68.7%, precision of 68.5%, recall of 67.8% and F1-score of 68.2% for the NBC algorithm. The SVM algorithm produces an accuracy of 80.5%, a precision value of 80.5%, a recall value of 79.6%, and an F1-score value of 79.6%. It can be seen that the SVM algorithm is superior to the NBC algorithm in all classification parameters. From several training and testing compositions, it was also found that the best composition was the 70:30 composition.
РАСШИРЕННЫЙ НЕОНАТАЛЬНЫЙ СКРИНИНГ: РЕЗУЛЬТАТЫ ОПРОСА ПЕДИАТРОВ И НЕОНАТОЛОГОВ
Authors: Кожевников А.С. , Серебрякова Е.Н. , Балдина Н.Ю. 
Published: January 2025

С 1 января 2023 года расширен перечень заболеваний, входящих в программу неонатального скрининга. Программа расширенного неонатального скрининга действует в каждом регионе Российской Федерации. Эффективность реализации программы расширенного НС зависит от информированности медицинских работников по вопросам организации и проведения мероприятий, включенных в программу расширенного НС, в частности, врачей педиатров и неонатологов, принимающих непосредственной участие в программе расширенного НС. Мы представляем результаты онлайн-анкетирования 74 врачей педиатров и неонатологов по вопросам организации и проведения расширенного НС. Результаты опроса показывают, что по ряду вопросов организации и проведения расширенного НС информированность врачей педиатров и неонатологов недостаточная, что требует проведения мероприятий, направленных на повышение информированности педиатров и неонатологов по вопросам расширенного НС.
From January 1, 2023, the list of diseases included in the neonatal screening program has been expanded. The expanded neonatal screening program operates in every region of the Russian Federation. The effectiveness of the implementation of the expanded NS program depends on the awareness of medical workers regarding the organization and implementation of activities included in the expanded NS program, in particular, pediatricians and neonatologists who are directly involved in the expanded NS program. We present the results of an online survey of 74 pediatricians and neonatologists on the organization and conduct of extended NS. The survey results show that the awareness of pediatricians and neonatologists on a number of issues related to the organization and conduct of extended NS is insufficient, which requires activities aimed at increasing the awareness of pediatricians and neonatologists on issues of extended NS.
СТАНДАРТ РАБОЧЕГО МЕСТА УЧАСТКОВОГО ПЕДИАТРА
Authors: Шаповалов К.А. , Каторкин В.И. , Лебедев В.С. , Габова Г.Ю. , Бабкина А.В. 
Published: January 2025

В рамках проекта «Бережливая поликлиника» с использованием базового инструмента – метода «5S» («5S») возникает необходимость разработки унифицированного стандарта рабочего места участкового врача-педиатра и медицинской сестры. Создание стандартной модели для организации максимально эргономичной, удобной и комфортной работы участкового врача-педиатра и медицинской сестры во время амбулаторного приёма. Стандарт рабочего места участкового врача-педиатра и медицинской сестры разработан в государственном бюджетном учреждении здравоохранения Республики Коми «Сыктывкарская детская поликлиника №3» («СДП №3»). При его разработке соблюдены и последовательно использованы все шаги «5S»: Шаг 1. Сортировка; Шаг 2. Соблюдение порядка; Шаг 3. Содержание в чистоте; Шаг 4. Стандартизация; Шаг 5. Совершенствование. Создание комфортных условий для работы участкового врача-педиатра и медицинской сестры, выполнения профессиональных операций, поддержание порядка, чистоты, аккуратности, экономия времени и энергии повышают удовлетворённость медицинских работников результатами труда и качество оказания медицинских услуг. Повышение качества производственных условий, последовательно приводящее к повышению качества труда, являются основным и, возможно, единственным путём к эффективному лечению, созданию комфортных условий и удовлетворённости качеством обслуживания детям и сопровождающим их родственников.
Within the framework of the "Lean Polyclinic" project using the basic tool – the "5S" ("5S") method, it becomes necessary to develop a unified standard for the workplace of a district pediatrician and nurse. Creation of a standard model for organizing the most ergonomic, convenient and comfortable work of the district pediatrician and nurse during an outpatient appointment. The standard for the workplace of a district pediatrician and nurse was developed in the state budgetary healthcare institution of the Republic of Komi "Syktyvkar Children's Clinic No. 3" ("SDP No. 3"). During its development, all the steps of «5S» were observed and consistently used: step 1 — sort; step 2 — set in order; step 3 — shine; step 4 — standardize; step 5 — sustain. Creating comfortable conditions for the work of the local pediatrician and nurse, performing professional operations, maintaining order, cleanliness, accuracy, saving time and energy increase the satisfaction of medical workers with the results of work and the quality of medical services. Improving the quality of working conditions, consistently leading to an increase in the quality of work, is the main and, perhaps, the only way to effective treatment, creation of comfortable conditions and satisfaction with the quality of service for children and their accompanying relatives.