bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reseña: Mario Agudo Villanueva, Macedonia. La cuna de Alejandro Magno. Madrid, Dstoria edicions, 2016, 254. pp [ISBN: 978-84-941455-7-5].
Authors: Molina Ignacio 
Published: March 2022

Reseña de Mario Agudo Villanueva, Macedonia. La cuna de Alejandro Magno. Madrid, Dstoria edicions, 2016, 254. pp [ISBN: 978-84-941455-7-5].
Reseña: J. D. Grainger, Antipater’s Dynasty: Alexander the Great’s Regent and his Successors, Barnsley, Pen & Sword Military 2019, 288 pp [ISBN 9781526730886]
Authors: Agudo Villanueva Mario 
Published: March 2022

Reseña de John D. Grainger, Antipater’s Dynasty: Alexander the Great’s Regent and his Successors, Barnsley, Pen & Sword Military 2019, 288 pp [ISBN 9781526730886].
Becoming Macedonian: Name Mapping and Ethnic Identity. The Case of Hephaistion
Authors: Reames Jeanne 
Published: March 2022

An epigraphical survey (with digital mapping component) of Greece and Magna Graecia reveals a pattern as to where Hephais-based names appear, up through the second century BCE. Spelled with an /eta/, these names are almost exclusively Attic-Ionian, while Haphēs-based names, spelled with an alpha, are Doric-Aeolian, and much fewer in number. There is virtually no overlap, except at the Panhellenic site of Delphi, and in a few colonies around the Black Sea.Furthermore, cult for the god Hephaistos –long recognized as a non-Greek borrowing– was popular primarily in Attic-Ionian and “Pelasgian” regions, precisely the same areas where we find Hephais-root names. The only area where Haphēs-based names appear in any quantity, Boeotia, also had an important cult related to the god. Otherwise, Hephaistos was not a terribly important deity in Doric-Aeolian populations.This epigraphic (and religious) record calls into question the assumed Macedonian ethnicity of the king’s best friend and alter-ego, Hephaistion. According to Tataki, Macedonian naming patterns followed distinctively non-Attic patterns, and cult for the god Hephaistos is absent in Macedonia (outside Samothrace). A recently published 4th century curse tablet from Pydna could, however, provide a clue as to why a Macedonian Companion had such a uniquely Attic-Ionian name.If Hephaistion’s ancestry was not, in fact, ethnically Macedonian, this may offer us an interesting insight into fluidity of Macedonian identity under the monarchy, and thereby, to ancient conceptualizations of ethnicity more broadly.
Berardinelli-Seip Syndrome: Report of an Old Case Successfully Treated with Anti-Glucocorticoid Therapy Followed by Bilateral Adrenalectomy
Authors: H. Contreras Patricio 
Published: March 2022

A female teenager was diagnosed in 1986 with Berardinelli-Seip syndrome (congenital generalized lipodystrophy). Following the predictable failure of the usual treatments for her severe type 2 diabetes and hypertriglyceridemia, we decided to treat her with a novel anti-glucocorticoid-centered approach. In 1988, we treated her with mifepristone alone (9 weeks), then with mifepristone combined with ketoconazole (1 week), and again, with mifepristone alone (2 weeks). Acanthosis nigricans, as well as eruptive xanthomas, experienced complete regression following the anti-glucocorticoid therapy. Moreover, the patient gained 7 kilograms. Besides, there was a striking metabolic amelioration with mifepristone therapy. The addition of ketoconazole strongly reduced the relevant mifepristone-induced hypercortisolemia within 1 week. Fasting serum glucose, insulin, and triglycerides fell from day 1 to day 7 without reaching values within the normal range. Two weeks after ketoconazole withdrawal (while keeping mifepristone administration), serum triglyceride and glucose values rose significantly. Eleven days after bilateral adrenalectomy, fasting glucose values were within normal limits or slightly above. An oral glucose tolerance test (75-g OGTT) performed 13 days after surgery showed insulin values within normal limits, fasting serum glucose values within the normal range, and a 2-h serum glucose value in the diabetic range. These findings were consistent with our working hypothesis proposing that Berardinelli-Seip syndrome is due to cortisol-mediated unrestrained lipolysis.
The Nemesia trapdoor spider fauna of the Maltese archipelago, with the description of two new species (Araneae, Mygalomorphae, Nemesiidae)
Authors: Cassar Thomas , Mifsud David , Decae Arthur E. 
Published: March 2022

Contrary to what its name suggests, Nemesia arboricola is not strictly arboreal in habit. Here we compare female specimens of N. arboricola collected from arboreal and terrestrial nests. We furthermore describe the male of N. arboricola for the first time as well as two recently discovered species of Nemesia (N. maltensis sp. nov. and N. cominensis sp. nov.). Nemesia maltensis is described from both sexes, N. cominensis is described from the female and a juvenile male specimen. For N. cominensis we discuss the sexual dimorphism of juvenile male and female spiders. Field observations and laboratory observations show remarkable features of the Maltese Nemesia fauna that are unknown from Nemesia species found elsewhere. Particularly, the arboreal dwellings of N. arboricola and the absence of a trapdoor to close off the burrow entrance in N. maltensis appear to be exceptional. The composition of the Maltese Nemesia fauna, as located in the central Mediterranean, is finally discussed in relation to the different Nemesia species-complexes occurring in the eastern and western Mediterranean basin.
AreToxoplasma-infected subjects more attractive, symmetrical, or healthier than non-infected ones? Evidence from subjective and objective measurements
Authors: Borráz-León Javier I. , Rantala Markus J. , Krams Indrikis A. , Cerda-Molina Ana Lilia , Contreras-Garduño Jorge 
Published: March 2022

BackgroundParasites are among the main factors that negatively impact the health and reproductive success of organisms. However, if parasites diminish a host’s health and attractiveness to such an extent that finding a mate becomes almost impossible, the parasite would decrease its odds of reproducing and passing to the next generation. There is evidence thatToxoplasma gondii(T. gondii) manipulates phenotypic characteristics of its intermediate hosts to increase its spread. However, whetherT. gondiimanipulates phenotypic characteristics in humans remains poorly studied. Therefore, the present research had two main aims: (1) To compare traits associated with health and parasite resistance inToxoplasma-infected and non-infected subjects. (2) To investigate whether other people perceive differences in attractiveness and health betweenToxoplasma-infected and non-infected subjects of both sexes.MethodsFor the first aim,Toxoplasma-infected (n= 35) and non-infected subjects (n= 178) were compared for self-perceived attractiveness, number of sexual partners, number of minor ailments, body mass index, mate value, handgrip strength, facial fluctuating asymmetry, and facial width-to-height ratio. For the second aim, an independent group of 205 raters (59 men and 146 women) evaluated the attractiveness and perceived health of facial pictures ofToxoplasma-infected and non-infected subjects.ResultsFirst, we found that infected men had lower facial fluctuating asymmetry whereas infected women had lower body mass, lower body mass index, a tendency for lower facial fluctuating asymmetry, higher self-perceived attractiveness, and a higher number of sexual partners than non-infected ones. Then, we found that infected men and women were rated as more attractive and healthier than non-infected ones.ConclusionsOur results suggest that some sexually transmitted parasites, such asT. gondii, may produce changes in the appearance and behavior of the human host, either as a by-product of the infection or as the result of the manipulation of the parasite to increase its spread to new hosts. Taken together, these results lay the foundation for future research on the manipulation of the human host by sexually transmitted pathogens and parasites.
Maternal Care in Private Sector, Colombo District, Sri Lanka; Profile and Factors associated with key Newborn Care Practices
Authors: Kumarasinghe M. , Kasturiaratchi K. , Senanayake P. , Perera S. , Irfaan S. , Samarasinghe W. S. , Dissanayake M. , Silva C. De 
Published: March 2022

Aims: Limited information is available on private sector contribution for maternal care in Sri Lanka. The main objective of this assessment is to describe the maternal and newborn characteristics of deliveries in private sector in Colombo District, Sri Lanka. Secondly, the assessment of the factors associated with key newborn care practices using the National Maternal and Newborn Health Management Information System of Private Health Institutions (NMNMIS-PHI)-Phase 1 was conducted.
Study design: Secondary descriptive analysis was performed using data reported in the NMNMIS-PHI-Phase 1, Sri Lanka.
Place and Duration of Study: All deliveries in private health institutions in Colombo District which were reported in the NMNMIS-PHI-Phase 1 was included in the study. The time period was from 1st January 2021 to 31st December 2021.
Methodology: Maternal, delivery and newborn characteristics of national vs. private sector in Colombo District were compared using Z test. Associated factors for key newborn care practices was calculated using univariate and multivariate Odds ratios.
Results: Incidence of Gestational DM was higher among pregnant women delivered at private sector, Colombo compared to national rate (17.9% vs. 7.1%, p<0.001). Further, the reported caesarean section rate in private sector was close to twofold that of the national rate (76.5% vs. 41.9%, p<0.001). Stillbirth rate of private sector in Colombo was comparatively low than the national rate (0.2% vs. 0.7%). Similarly, reduced number of low-birth-weight newborns was reported in private sector in comparison to national figure (12.4% vs. 13.9%). Significantly more newborns of primi-pregnant women received skin-to-skin contact (SSC) immediately after birth compared to newborns of multi-parous women (AOR=0.814, CI=0.735-0.900, p<0.001).
Conclusion: Maternal and neonatal characteristics of pregnant women delivered in private sector in Colombo was significantly different from the national profile of pregnant women. Promotion of immediate SSC and reduction in unnecessary caesarean sections should be considered in private sector deliveries in Sri Lanka to further enhance the positive maternal and newborn outcomes.
Eisenia fetida Squirms Biased Bioremediation of Pyrene and Indeno(1, 2, 3–cd)Pyrene Soil and Petroleum Wastewater Contamination
Authors: Fawole C. , Dashak D. A. , Salami S. J. , Abdulmumin S. , Larbong M. R. , Chimezie-Nwosu H. A. 
Published: March 2022

Raw mean levels of pyrene (pyr) and indeno(1,2,3-cd)pyrene petroleum wastewater were 8.00±0.00 and 9.20±0.03 mg/L respectively. Petroleum wastewater impacted soil gave Pyr (8.00±0.01) and Ind (9.50±0.00) mg/kg. The biased and effective nature of Eisenia fetida vermiaccumulated Pyr (6.94±0.02 mg/kg) and Ind (7.56±0.01 mg/kg), had vermiremoval efficiency of Pyr (86.75%) and Ind (82.17%). Thus, the treatment unit indicated Pyr (0.07±0.00 mg/kg) and Ind (0.00±0.00 mg/kg) for soil with petroleum wastewater sample while petroleum wastewater sample was Pyr (0.00±0.00 mg/L) and Ind (0.00±0.00) within 5 weeks detention period. Identifications and quantifications of the two polycyclic aromatic hydrocarbons (2PAHs) Pyr and Ind were carried out by GC/MD in accordance to manufacturer’s operational specifications. E. fetida squirms were proven bioremediation tools, capable to remove or detoxify the two environmental health contaminants from the contaminated pilot ecosystem.
Effect of General Heath State, Therapy Satisfaction, INR Control on Quality of Life in Warfarin Patients
Authors: Iqbal Muhammad Shahid , Khan Salah-ud-Din 
Published: March 2022

Objective: This study aimed to assess effect of general heath state, therapy satisfaction and INR control on quality of life in warfarin patients.
Methods: A cross-sectional study using a newly developed and validated research tool was conducted in patients on warfarin. Data was collected by convenience sampling method. Descriptive, comparative, and inferential statistics were used by Statistical Package for the Social Sciences (SPSS) ver. 24 to determine the sociodemographic correlates of warfarin knowledge in warfarin patients.
Results: Among total 275 studied warfarin patients, the majority of the studied warfarin patients were females than males (n=184, 62.4%, and n=111, 37.6% respectively). A total of 188 (63.7%) patients were satisfied from their healthcare providers while 107 (36.3%) were not satisfied from healthcare providers. Around 128 (43.4%) of the patients were actively managing their disease while 167 (56.6%) of the patients were not able to actively manage their disease.
Conclusion: These results confirmed that overall study participants had moderate effect of QoL on general heath state, therapy satisfaction, and INR control among patients on warfarin.
Testicular Mass with Liver Metastasis: A Case Report
Authors: Gawande Yamini , Tivaskar Suhas , More Akash , Luharia Anurag 
Published: March 2022

Background: A malignancy of testicles is known as testicular cancer. The testicles are positioned directly below the penis in the scrotum. The testicles' purpose is to create sperm for reproduction. A lump in the testicles and pain or swelling in the scrotum are the possible symptoms. Infertility may occur as a result of treatment. An undescended testis, a family history of the disease, and a previous history of testicular cancer are all risk factors. Germ cell tumors, which are split into seminomas and non-seminomas, are the most prevalent form. Sex-cord stromal tumors and lymphomas are two more forms. Liver metastasis is a cancerous tumor that has spread to the liver from another organ that has been impacted by malignancy. In liver metastases, the malignant cells that develop are not liver cells. They are cancer cells from the region of cancer's genesis in the body. Cancer has progressed to the liver from another portion of the body, doctors may refer to the metastatic liver disease as stage four or modern cancer. The incidence of primary liver cancer is lower than that of liver metastases: cirrhosis or hepatitis are common risk factors in persons with primary liver cancer.
Case Presentation: We present a case of a 24-year-old male with complaints of mass in left testis for the past one and half years. The mass was slow-growing, non-painful. The patient complained of heavy feeling in the lower abdomen with a recent history of loss of appetite, weight loss, and backache. The diagnosis was done with the help of ultrasound, blood tests, computed tomography (CT), magnetic resonance imaging (MRI) scan imaging & treated with excision.
Conclusion: Testicle’s malignancy is regarded as an oncologic achievement because more people will be treated with an amalgamation of chemotherapy and surgery. The radiologists are crucial in finding cancers throughout the patient presentation, correctly grading illness, and detecting recurrence malignancy during scanning monitoring. A case of Testicle’s malignancy and liver metastasis in a twenty-four-year-old man that had managed with a multicentric approach. Genetic counseling and psychological assistance should be provided to the family of a person presenting with the testicular mass as a part of the genetic condition.
Sub-acute Toxicity and Safety Study of Mecca Myrrh (Commiphora opobalsamum) by Experimental Histological Analysis
Authors: Khan Lateef M. , Ahmad Mai A. Alim A. Sattar , Al – Salmi Akram A. , Ali Soad S. 
Published: March 2022

Background: The native herbal medicinal products are vital source of the key medication; their excellent dogmatic safety study is of prime importance despite their strong validated evidence of efficacy.
Aim: To study the sub-acute toxicity of Commiphora opobalsamum (CO) by histological analysis of vital organs.
Methods: Twenty-four male Wister rats of 10-12 weeks age were used. Oral toxicity studies with repeated dose were accomplished in four group of rats, six rats were included in each group. Three groups of rats were administered CO orally in the graded doses of 250,500, and 1000 mg/kg/day once daily for 14 days Vs normal control. Determination the relative weight of vital organs and their histological changes were performed at the end of the study. Subsequently, the digital images of the CO - administered groups were equated with the control group.
Results: Intriguingly, the relative weights of the vital organs, performed following 14 days of graded doses of CO given were equated with the control group, significant differences were not detected (p˃0.05). Furthermore, histological examination of the brain demonstrated no changes in its cellular neuronal components Regarding the heart, CO extract did not produce any histological changes, insignificant changes were observed in liver parenchyma of rats, regarding the kidney, no degenerative changes were noticed in glomerular tuft capillaries or renal tubular epithelium, conversely trivial changes were observed in liver parenchyma. Finally, no minor histological changes were observed in stomach (high dose) and spleen tissue of animals on comparison with the control group.
Conclusion: Seemingly, the impressive outcome of this fundamental histological scrutiny of methanolic extract of CO demonstrated an imperative facet of safety and correspondingly displayed the key feature of its nontoxic medicinal application for short term supplementation.
Attitude and Mental Health Effects Related to COVID 19 in Dental Patients
Authors: Kumar Sudesh , Abidi Syed Yawar Ali , Habib Muhammad Elham , Sajjad Isma , Adnan Samira , Lone Maham Muneeb , Suleman Sarmad 
Published: March 2022

Objectives: The objective of this study was to compare the mental health effects and attitude of male and female patients visiting Dental OPD during the COVID-19 pandemic.
Materials and methods: This Descriptive study was conducted amongst patients visiting dental setup of Jinnah Sindh medical university and Jinnah postgraduate center. Consent was taken before participation in the study. Patients visiting dental OPD (SIOHS and JPMC) were requested to fill the hardcopy of the questionnaire. Co-authors translated and filled the questionairre for those patients who were unable to read and write. Mental health status and attitude regarding COVID-19 were assessed through closed-ended questions.
Results: Compared to males, females were more afraid of becoming infected with COVID-19 (p-value 0.018), affected more emotionally with COVID-19 pandemic (p-value 0.042), were wearing mask more frequently (p-value 0.038) and were more afraid dental treatment due to COVID-19 (p-value 0.023). With increase in qualification there was increase in COVID-19 fear (p-value 0.028), emotional effect (p-value 0.000) and effect on daily routine (p-value 0.002).
Conclusion: Majority of the participants visiting the dental OPD were unaware of the preventive measures to protect themselves from COVID-19. As compared to males, female patients were more concerned and had a positive attitude towards protection from COVID-19. Furthermore, this attitude was more in people who were more educated.
Exercise Electrocardiogram Testing in Asymptomatic Patients with Diabetes and Left Ventricular Diastolic Dysfunction
Authors: Amjad Hira , Sharif Ifrah , Ali Shazam 
Published: March 2022

Objectives: The main objective of the study is to find the exercise electrocardiogram testing in asymptomatic patient with Type-II diabetes and left ventricular diastolic dysfunction.
Materials and Methods: This descriptive study was conducted Fatima Jinnah Hospital, Lahore during January 2019 to November 2019. The data was collected from 50 patients of type II DM. These all patients has normal electrocardiogram (ECG) and normal systolic function.
Results: The data was collected from 50 patients of both genders. The mean age of the patients was 47.83±5.61 years. After getting data the results were divided into two parts. There were 25 patients in group A and 25 patients group B. The mean duration of diabetes is 2.5±5.61 years. There were 20 males and 30 females in this data. There were no significant difference of fasting blood sugar in both groups. There was no statically significant difference between two groups regarding left atrial dimension, aortic root dimension, LV end-diastolic dimension, ejection and LV mass.
Conclusion: It is concluded that It is concluded that coronary supply route sicknesses is a typical issue in DM, with diastolic brokenness and increment uniquely in patients with positive pressure practice electrocardiography.
Evaluation of Dental Anxiety in Children by Estimating the Salivary Cortisol Levels before and after Dental Procedures
Authors: Sankar Pavithiraa , Subramanian E. M. G. 
Published: March 2022

Aim: Dental procedures in general range from simple examination to complex stressful procedures like extractions. This can cause varied levels of anxiety in children based on the severity and duration of the procedure. This study was designed with the aim to assess changes in salivary cortisol levels due to the various dental procedures carried out in children.
Materials and Methods: The sample consisted of a total of 30 children of the 5-9 age group whose parents consented to examination and further treatment. Children who had been given a Frankl score of positive (+) or definitely positive (++) upon initial examination were only included in the study. Children with negative (-) and definitely negative (--) Frankl scores, any history of systemic diseases, on corticosteroid therapy, having fever, or medically compromised were excluded from the study. Unstimulated saliva was collected before and after the procedure and was analysed using ELISA. The data collected was statistically analysed and assessed for significance.
Results: Out of the 30 children 17 were boys and 13 were girls and the difference was statistically insignificant. There was no significant difference in age between the genders (P = 0.12). Paired t - test was done to analyse the intra group data and ANOVA test was done to compare between the groups. Compared to the three procedures restorative was least stressful whereas extractions were most stressful and this result was statistically significant.
Conclusions: Within the limitations of this study, we can conclude that salivary cortisol is a good indicator of acute stress. Extraction procedures seem to be the most stressful of all the procedures.