bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diane Berthelette, professeure titulaire retraitée
Authors: Faye Cheikh 
Published: February 2022

Diane Berthelette est un nom connu et familier, ici au Québec et dans la francophonie, aux personnes qui s’intéressent à la santé et sécurité au travail (SST) ainsi qu’à la recherche évaluative. Elle est d’abord une universitaire accomplie au parcours qui force le respect. En effet, cumulativement à ses activités de recherche et d’enseignement, madame Berthelette était très impliquée dans le fonctionnement de l’UQAM : elle y occupait plusieurs fonctions de nature pédagogique, administrative et/ou syndicale (direction de programmes, présidence du Comité d’éthique de la recherche, membre de la Commission des études, membre du CA de l’institution, etc.).
Elle est aussi une personne-ressource dévouée aux causes de la collectivité, comme le montrent les nombreux et importants mandats qui lui ont été confiés en dehors de l’Université. Au nombre de ces mandats figurent celui d’administratrice, puis de vice-présidente du CA du Fonds de recherche du Québec – Société et culture (FRQSC), de présidente d’un groupe de travail ou d’un comité consultatif institué auprès de certains départements ministériels de la province, de membre du CA de l’Institut national de santé publique du Québec et, le dernier et non le moindre, de PDG du Centre de liaison sur l’intervention et la prévention psychosociales (CLIPP).
La jouissance d’une retraite bien méritée ne l’empêche pas de continuer à se rendre utile. C’est ainsi que madame Berthelette poursuit ses activités scientifiques, notamment à titre de conseillère scientifique auprès du FRQSC.
La revue Organisations & Territoires retrace avec Diane Berthelette son riche parcours pour mettre en lumière certains aspects ayant entouré l’essor de la SST au Québec au cours des 20 dernières années, alors qu’elle en fut une actrice et une témoin privilégiée.
Carole Dionne, professeure en sciences infirmières
Authors: Desjardins France , Simard Jeanne 
Published: February 2022

Depuis plus de 20 ans, la professeure Carole Dionne s’implique au sein de différents organismes à but non lucratif. Sa générosité et son dévouement envers sa communauté l’ont menée à une mise en candidature aux prix Hommage bénévolat-Québec en 2018. Son implication lui permet de mobiliser différents professionnels autour d’enjeux importants pour le développement de la société et de réaliser des projets communs et structurants pour aider les personnes plus vulnérables.
Madame Dionne est membre du conseil d’administration du Centre de prévention du suicide 02 et de l’Association canadienne pour la santé mentale section Saguenay. Depuis 2017, elle est présidente de la corporation à but non lucratif Hébergement Plus, dont la mission est de promouvoir le développement, le maintien et l’amélioration de l’habitation communautaire destinée à des personnes ou à des familles à revenus faibles ou modestes; à des personnes âgées en perte d’autonomie; et à des personnes ayant des problèmes particuliers, dont les itinérants, les personnes ayant une déficience intellectuelle ou physique ainsi que les femmes victimes de violence. Cette corporation est notamment propriétaire du service des Habitations du Parc, soit 99 logements destinés à des personnes vivant avec une déficience intellectuelle ou physique ou un trouble du spectre de l’autisme.
APT1-Mediated Depalmitoylation Regulates Hippocampal Synaptic Plasticity
Authors: Shen Zu-Cheng , Xia Zhi-Xuan , Liu Jian-Min , Zheng Jie-Yan , Luo Yu-Fei , Yang Han , Li Meng-Die , Cao Ting , Liu Hai-Ping , Jin Gui-Lin , Huang Hui-Hui , Yu Chang-Xi , Zhou Jun 
Published: February 2022

Palmitoylation may be relevant to the processes of learning and memory, and even disorders, such as post-traumatic stress disorder and aging-related cognitive decline. However, underlying mechanisms of palmitoylation in these processes remain unclear. Herein, we used acyl-biotin exchange, coimmunoprecipitation and biotinylation assays, and behavioral and electrophysiological methods, to explore whether palmitoylation is required for hippocampal synaptic transmission and fear memory formation, and involved in functional modification of synaptic proteins, such as postsynapse density-95 (PSD-95) and glutamate receptors, and detected if depalmitoylation by specific enzymes has influence on glutamatergic synaptic plasticity. Our results showed that global palmitoylation level, palmitoylation of PSD-95 and glutamate receptors, postsynapse density localization of PSD-95, surface expression of AMPARs, and synaptic strength of cultured hippocampal neurons were all enhanced by TTX pretreatment, and these can be reversed by inhibition of palmitoylation with palmitoyl acyl transferases inhibitors, 2-bromopalmitate and N-(tert-butyl) hydroxylamine hydrochloride. Importantly, we also found that acyl-protein thioesterase 1 (APT1)-mediated depalmitoylation is involved in palmitoylation of PSD-95 and glutamatergic synaptic transmission. Knockdown of APT1, not protein palmitoyl thioesterase 1, with shRNA, or selective inhibition, significantly increased AMPAR-mediated synaptic strength, palmitoylation levels, and synaptic or surface expression of PSD-95 and AMPARs. Results from hippocampal tissues and fear-conditioned rats showed that palmitoylation is required for synaptic strengthening and fear memory formation. These results suggest that palmitoylation and APT1-mediated depalmitoylation have critical effects on the regulation of glutamatergic synaptic plasticity, and it may serve as a potential target for learning and memory-associated disorders.SIGNIFICANCE STATEMENTFear-related anxiety disorders, including post-traumatic stress disorder, are prevalent psychiatric conditions, and fear memory is associated with hyperexcitability in the hippocampal CA1 region. Palmitoylation is involved in learning and memory, but mechanisms coupling palmitoylation with fear memory acquisition remain poorly understood. This study demonstrated that palmitoylation is essential for postsynapse density-95 clustering and hippocampal glutamatergic synaptic transmission, and APT1-mediated depalmitoylation plays critical roles in the regulation of synaptic plasticity. Our study revealed that molecular mechanism about downregulation of APT1 leads to enhancement of AMPAR-mediated synaptic transmission, and that palmitoylation cycling is implicated in fear conditioning-induced synaptic strengthening and fear memory formation.
Understanding the societal and business perspectives of online trust literacy in the context of digitalization
Authors: Cserdi Zsófia , Fehér Péter , Gáti Mirkó , Rab Árpád , Varga Krisztián 
Published: February 2022

Abstract
The spread of digital culture is one of the biggest reprogramming of humanity, radically transforming our economic, social, and cultural models. One of the keys to success of this transformation, and to preventing the spread of digital divides, is the development of a variety of literacies. These literacies describe the success of society and business to thrive in the digital space. In this article, we introduce a new concept of action literacy (online trust literacy) and examine its functioning from both a social and a business perspective through two primary research studies. After defining the phenomenon, we examine it from two sides: the first part examines the dimensional structure of trust from the perspective of society (through a large, representative sample-based survey), while the second part analyses the building and operational mechanisms of trust from a business perspective (through a small sample of exploratory data collection). The main implications of this study are to demonstrate the Janus-faced nature of this new kind of literacy and the ambiguity of digital culture to better understand the toolset of information recipients and providers. The result of our research is the introduction of a new concept of action literacy and its operationalisation, resulting in an interpretation matrix.
Advanced materials supply considerations for electric vehicle applications
Authors: Lipman Timothy E. , Maier Petra 
Published: February 2022

AbstractElectric vehicles are now proliferating based on technologies and components that in turn rely on the use of strategic materials and mineral resources. This review article discusses critical materials considerations for electric drive vehicles, focusing on the underlying component technologies and materials. These mainly include materials for advanced batteries, motors and electronics, lightweight structures, and other components specific to each vehicle type. Particularly strategic and widely used minerals and elements/structures for electric vehicles include nickel, cobalt, rare-earth minerals, lightweight and high strength steel alloys and underlying metals (e.g., magnesium and aluminum), carbon fiber, graphite and graphene, copper, and steel alloying materials. Additional key considerations include those around component and vehicle supply chains, repurposing and recycling vehicle components at end of vehicle life, and environmental and humanitarian considerations around the extraction and transport of the evolving set of materials needed for modern electric vehicle production.
Graphical abstract
Bitcoin kaotik analizi ve fiyat tahmin modeli önerisi
Authors: Çağlar Hatice Nazan 
Published: February 2022

Kaos Teorisi, doğrusal olmayan dinamik sistemlerin davranışlarını tanımlar ve ekonomi alanında pek çok verinin modellenmesinde kullanılır. Kaos teori, sistemin doğrusal olmayan ve deterministik bir süreç olduğu varsayımlarına dayanır. Doğrusal modeller, ekonometrik sistemleri karmaşıklıklarını ortaya çıkarmakta yetersiz kalmaktadır. Bu çalışmanın amacı, Bitcoin günlük fiyatlarının zamana bağlı doğrusal olmayan dinamik bir sistem tarafından üretilip üretilmediğini araştırmak ve sistemin uzun vadede geleceğe yönelik tahmin yeteneğini araştırmak ve bir tahminleme modeli oluşturmaktır. Birçok ekonomik veri serisinin kaotik davranış gösterdiği bilinmektedir. Bu çalışmada, Bitcoin fiyatlarının kaotik yapısı incelenmiş ve regresyon yöntemi kullanılarak tahmin modeli kurulmuştur. Diğer bir ifadeyle amaç, Bitcoin fiyatlarının getirilerinin kaotik bir davranış gösterip göstermediğini ortaya koyarak elde edilen gömme (embedding) boyutuna bağlı olarak regresyon yöntemini kullanarak tahmin modeli oluşturmaktır. Çalışmada, 2021 Şubat – 2021 Kasım döneminde günlük kapanış fiyatı ( $ ) veri olarak kullanılmıştır. (URL-1,2021)
El primer Francisco Brines: Las Brasas y palabras a la oscuridad
Authors: Jiménez Millán Antonio 
Published: February 2022

RESUMEN: El presente trabajo se centra en los dos primeros libros del poeta valenciano Francisco Brines (1932-2021), Las brasas (1960) y Palabras a la oscuridad (1966), haciendo una breve referencia al poema El Santo Inocente, editado en Madrid en 1965 e incluido luego en Materia narrativa inexacta. Establecemos tres apartados: en el primero se estudia el libro Las brasas, premio Adonáis de 1959, un título que ya revela el sentido elegíaco de la poesía de Francisco Brines: alude al rescoldo de un fuego más intenso, que es la vida, y, desde el inicio, se impone la conciencia del desgaste ocasionado por el paso del tiempo. El segundo apartado trata sobre la lectura que hizo Brines de la poesía de Luis Cernuda en el artículo «Ante unas poesías completas», publicado en la revista La Caña Gris (1962), donde se revelan muchas afinidades con el poeta sevillano de la generación del 27. El tercer apartado estudia un libro de poemas mucho más extenso, Palabras a la oscuridad (1966), premio de la Crítica en 1967. Es el libro que contiene más poemas amorosos en la obra de Brines, y paralelamente destacan los viajes y las referencias culturales, afirmándose ya una voz poética que apenas va a experimentar variaciones en los siguientes libros, hasta La última costa (1996).
PAlABRAS CLAVE: Francisco Brines; Luis Cernuda; poesía reflexiva; vitalismo; elegía.
About the permanent drainage of the ventricle of the brain with its dropsy
Authors: Perimov Viktor A. 
Published: February 2022

In many intracranial diseases, it was precisely the symptoms of increased cerebral pressure that forced one to resort to surgical intervention, which gave excellent results: for example, removal of hematomas and ligation of the vessel in case of bleeding from the arteria meningea media or opening of brain abscesses.
Equally severe symptoms of pressure on the brain can be caused by accumulations of cerebrospinal fluid in the ventricles of the brain, as is observed in cases of acute head dropsy (acutus int.) e.g. in meningitis serosa or tuberculosa, as well as in chronic congenital and secondary internal dropsy of the brain. The thought of surgeons has long been directed in this direction. Back in 1881, Wernicke experimentally proved the usefulness of ventricular puncture in such cases. Bergmann was the first to perform this operation in 1888. Since then, many surgeons with varying happiness have performed this operation.
About the regulation of the movement of the stomach
Authors: Polumordvinov Dmitry V. 
Published: February 2022

Our knowledge of the movements of the stomach has been considerably enlarged in recent years, thanks to the introduction of fluoroscopy into the range of physiological methods of investigation.
True, much of what was discovered in this case was already well known to physiologists from the indications of other methods, but many new and interesting facts are due entirely to fluoroscopy. Thus, at the present time, we can consider as established and demonstrated ad oculos the typical pattern of gastric movements that develop during the period of gastric digestion.
Méret. Facial neuralgia cured by high frequency current. Neuralgie faciale quérite par le caurant, coutinu a haue fréquence. — Archives d'électr médic. 1909, p. 419
Authors: Likhnitsky V. 
Published: February 2022

A case of persistent bilateral trigeminal neuralgia lasting 5 months; complete disappearance of pain after 10 sessions of topical application of high voltage currents according to the Bergonier method.
The Bergonier method, according to the author, in persistent neuralgias gives results that are not inferior to those obtained with injections of alcohol.
Menstrual problems of adolescent girls attending urban tertiary care hospital: One-year study
Authors: Thaker Rajal , Vasava Dipit , Patel Foram , Tyagi Aditi , Gavaniya Gautam , Dadhaniya Dhruvi 
Published: February 2022

Many adolescent girls with menstrual disturbances never present to their family doctor or gynaecologist due to embarrassment about discussing menstruation and fear of disease. This may lead to delayed presentation. The objective of the current study was to evaluate the socio-demographic aspects of adolescent girls having menstrual problems as well as type of menstrual problems and its management.This retrospective study was carried out at the department of obstetrics and gynaecology of tertiary care teaching hospital from July 2019 to July 2020. Total of 141 adolescent girls visited our hospital with menstrual problems. Amongst them 90(63.8%) belonged to the late adolescent group, 135(95.7%) were residing at urban areas, 70(49.6%) were from middle socio-economic class and 126(89.3%) were unmarried. Dysmenorrhoea, menstrual irregularities and amenorrhoea were present in 86(61%), 38(27%) and 17(12%) respectively. Patients were managed either medical and/or surgical management along with proper counselling. Majority of the adolescent girls in our study were anaemic. Hence, prevention and management of anaemia along with health education regarding normal physiology, various menstrual problems and importance of nutrition is necessary. In India attempts and success to develop adolescent friendly health services in public and private systems have met with partial success. Hence, counselling and management of menstrual problems in adolescents needs to be provided in existing health and medical care services.
To evaluate histopathological changes in placenta of IUGR
Authors: Mukhopadhyay Susmita , Natu Neeta , Anand Khushboo 
Published: February 2022

The present study entitled “To evaluate Histopathological changes in Placenta of IUGR” was conducted in the Department of Obstetrics and Gynaecology. A total of 400 patients were studied. Out of them 200 were normal patients without IUGR and 200 with IUGR. These patients were evaluated with the help of semistructured proforma consisting of various socio-demographic and clinical variables.Number of LSCS deliveries in IUGR patients (59) is significantly more than control group (33).The number of syncytial knot formation (&#62;10) in IUGR is 169 compared to 153 of control and hence is statistically insignificant. Cytotrophoblastic proliferation (&#62;10) in IUGR (126) is significantly more than (92) in the control group. Number Of area fibrinoid necrosis in villi &#62; 5 in IUGR group is 57 compared to control group (29) (significantly higher) No. of hylinized areas (&#62; 5) in IUGR (101) is significantly higher than in control group (68). Histopathological findings in low power field like syncytial knot formation, cytotrophoblastic cellular proliferation, calcification and hyalinisation of villi are also found as normal aging changes in placenta but it occur early and more frequently per low power field in IUGR group. To conclude, these morphological & histological findings of placenta are the etiological basis for Intra uterine growth restriction.
Is vertical transmission that dreadful in COVID 19 pregnancy
Authors: Nadyal Shreyas Raghavan , Niveditha Sakinala , Janaki V 
Published: February 2022

: Since the emergence of coronavirus illness in 2019 (COVID-19), there has been discussion on whether pregnant women are more vulnerable to COVID-19 and whether there is any vertical transmission through the placenta.: We describe a collection of thirty placentae collected from pregnant women who were tested at our hospital for SARS cov-2 infection by RT-PCR and turned to be positive. They were divided based on clinical symptoms into asymptomatic, mild and moderate groups before giving birth. We performed a thorough histopathological examination of placental tissue, RTPCR of amniotic fluid and placentae, between April 2021 and July 2021. All were term deliveries (between 37 and 39 gestational weeks). Sixty percent were asymptomatic and 23% had mild symptoms, 17% had moderate symptoms. On histopathologial examination, signs of maternal and/or foetal malperfusion were present in 36.6% of cases, which can be explained by the presence of altered coagulative or microangiopathic state induced by SARS-CoV-2.Inspite of the fact that most of the neonates born to mothers with COVID 19 positive status, were tested negative for SARS CoV 2 by RTPCR, we observed that COVID 19 in term patients admitted for delivery is associated with increased rates of placental histopathological abnormalities particularly fetal vascular malperfusion and villitis of unknown cause. These findings seem to occur even among asymptomatic term patients.
To study the role of serum lactate dehydrogenase in prediction of adverse outcomes of pre-eclampsia and eclampsia
Authors: Mukhopadhyay Susmita , Natu Neeta , Anand Khushboo 
Published: February 2022

The present study was carried out in the Department of Obstetrics and Gynaecology, with an aim to study the role of Serum Lactate Dehydrogenase in prediction of adverse outcomes of pre-eclampsia and eclampsia. The patients were selected from patients who were admitted to as emergency cases in labour room patients were irrespective of age and parity. On a specially designed proforma for this study, the patient particulars like detailed obstetric history, examination and laboratory findings were studied.Among the cases studied 76% preeclampsia and 96% eclampsia patient were unbooked case and most of them resided in rural areas while the remaining were from urban slums. Hyperbilirubinemia was seen in small groups of pre-eclampsia and eclampsia patients. Deranged level of liver enzyme were also found in small group of pre-eclampsia and eclampsia patients. LDH level was found significant higher (more than 600 IU/L) in pre-eclampsia and eclampsia patients. Eclampsia is associated with significant maternal and perinatal morbidity and mortality. The higher mortality is due to high percentage of the patient being unbooked and majority received no therapeutic intervention until admission. Among the cases studied 76% preeclampsia and 96% eclampsia patient were unbooked case and most of them resided in rural areas while the remaining were from urban slums. Hyperbilirubinemia was seen in small groups of pre-eclampsia and eclampsia patients. Deranged level of liver enzyme were also found in small group of pre-eclampsia and eclampsia patients. LDH level was found significant higher (more than 600 IU/L) in pre-eclampsia and eclampsia patients.
Cervical ectopic pregnancySuccessful management by combined systemic methotrexate, bilateral uterine embolization and suction evacuation
Authors: Gupta Paridhi , Chawla Indu , Kumari Kanika 
Published: February 2022

: A 31-year female, G4P2L2A1 with two previous cesarean deliveries and one dilatation and curettage, was diagnosed with cervical ectopic pregnancy of 8 weeks and two days without any cardiac activity. She had a complaint of slight pain in the abdomen without any bleeding per vagina. She was initially managed with multi-dose systemic methotrexate therapy. The value of beta-HCG decreased by about 70%. She then underwent bilateral uterine artery embolization followed by ultrasound-guided suction evacuation with descending cervical artery ligation with cervical balloon tamponade. The patient was asymptomatic throughout her hospital stay. Her beta-HCG value dropped to 10 IU/ml and usg showed empty endocervical canal on weekly follow-up.: Conservation methods like systemic methotrexate or potassium chloride, along with minimally invasive techniques like bilateral uterine artery embolization, are among the most effective and safe fertility-sparing modalities in managing cervical ectopic pregnancy. Proper case selection and availability of required infrastructure at tertiary care centers are mandatory.
Complete heart block in fetus – A rare combination of maternal autoimmune disorder and fetal structural cardiac disease – A case report and review of literature
Authors: Nasrin  , Vijaya  , Smrithi  
Published: February 2022

Majority of rhythm disturbances detected by fetal echocardiography are self-limiting. Appropriate work up of dysrhythmias is essential to prevent further damage of fetal conducting system and to initiate fetal therapy thereby reducing fetal losses. 25 year old Primi, 31 weeks of gestation, no comorbidities, was referred to our Antenatal OPD as severe fetal bradycardia. Antenatal Fetal Echo revealed third degree heart block with no evidence of hydrops. Maternal serum workup revealed autoimmune etiology. Fetal therapy started and Pregnancy followed up weekly till term gestation to deliver an alive baby by vaginal delivery. Baby was diagnosed to have Large ASD with a large PDA having bidirectional shunt by paediatric cardiologist. Surgical management was done by PDA ligation and permanent pacemaker. Unfortunately, baby succumbed due to respiratory failure and sepsis, as it was high risk complete heart block with multifactorial causation. Fetal bradyarrhythmia need to be evaluated carefully both for maternal autoimmune disorders and intrinsic cardiac causes of fetus. This case is reported for its rarity of having both etiologies presenting together as third degree or complete heart block.