bluuebunny/crossref_metadata_2025_split huggingface dataset:
More than handmaids: Nursing, labor activism and feminism
Authors: Lingel Jessa , Clark-Parsons Rosemary , Branciforte Kim 
Published: February 2022

AbstractIn the United States, the nursing profession has been dominated by women, who constitute nearly 90% of the workforce. The profession's popularity among women has consequences for gendered assumptions about labor: unions represent a key path for demanding equitable working conditions, yet the gendered framing of nursing has undermined efforts at building a labor movement within the profession. We offer two contributions with this paper: documenting the working lives of women nurses at a pediatric hospital in Oakland, CA, and unpacking the interrelated tensions between nursing, union work, and feminism. Drawing on interviews with 10 women nurses at Children's Hospital Oakland, we analyze the complex negotiations between gender and feminism that emerge in the everyday lives of union nurses. We use the concept of feminist agency as an organizing principle for understanding the disconnects between nurses and feminist discourse, and the affordances of labor activism for gaining workplace equity and mobilizing broader commitments to health justice.
How augmented reality media richness influences consumer behaviour
Authors: de Amorim Inês Pessoa , Guerreiro João , Eloy Sara , Loureiro Sandra Maria Correia 
Published: February 2022

AbstractThe current paper explores the impact that an augmented reality shopping assistant may have on consumers’ emotional and cognitive responses, and how it would affect their buying behaviours. A prototype of an application to assist consumers inside a supermarket was developed using HoloLens glasses. A total of 85 participants were invited to walk‐through the store using augmented reality glasses. A PLS‐SEM approach was used to test the conceptual model. Results using different scenarios show that media richness (the level of information cues, variety and immediate feedback) impacts consumer decisions and heightens their cognitive and emotional responses. The current study finds that a media‐rich augmented reality experience influences brand engagement and willingness to buy through perceived information quality and brand attitudes. At a time when managers in every industry work to capture consumers’ attention, the present study shows how content remains important in every communication activity, even in an innovative augmented reality retail shopping experience.
Topical dapsone in the treatment of acne: a systematic review
Authors: Nickles Melissa A. , Lake Eden 
Published: February 2022

AbstractBackgroundAcne is one of the most common dermatological disorders. Initial therapies for acne include topical retinoids, benzoyl peroxide, and topical clindamycin. However, patients who fail initial therapies may benefit from alternative topicals, including dapsone gel.ObjectiveTo analyze the current literature studying the efficacy of topical dapsone in the treatment of acne.MethodsPubMed, Embase, and Cochrane Library were systematically searched for clinical trials examining the efficacy of topical dapsone in the treatment of acne.ResultsFourteen studies were included in the analysis. Dapsone monotherapy showed a treatment success rate of 40.1–69.4% for dapsone gel 5% and 29.8–47.0% for dapsone gel 7.5% when used for 12–16 weeks. In all studies, inflammatory lesions decreased by a larger percentage than noninflammatory or total lesions. Dapsone gel was also studied in combination with various other acne treatments, including doxycycline, oral isotretinoin, benzoyl peroxide, and topical retinoids. While mild treatment‐related adverse effects, most commonly consisting of skin irritation, occurred in 2.0–75.0% of participants, no major treatment‐related adverse effects were reported.LimitationsLimitations of the study include variable treatment regimens making it difficult to compare results across studies. Additionally, adverse effects and skin irritation were reported differently, and potential selection biases exist in the randomized trials.ConclusionDapsone gel offers a safe and promising alternative therapy for patients with difficult to treat acne or those who experience adverse effects to first‐line therapies.
Profile of antiphospholipid antibodies in HIV‐infected and HIV‐uninfected women with a history of thrombosis
Authors: Schapkaitz Elise , Libhaber Elena , Jacobson Barry F. , Gerber Annika , Rhemtula Haroun , Büller Harry R. 
Published: February 2022

AbstractIntroductionIncreased antiphospholipid antibodies (aPL) have been described in human immunodeficiency virus (HIV) infection. However, the association between aPL and the increased risk of thrombosis in HIV requires further clarification.MethodsWe reviewed the medical records of 215 consecutive women with a history of thrombosis and/or obstetric complications (158 HIV‐uninfected and 57 HIV‐infected) between July 2017 and March 2021. Participants (n = 215) without clinical criteria manifestations for antiphospholipid syndrome were included as matched controls. Testing for lupus anticoagulant (LAC), anticardiolipin (aCL) and anti‐beta2‐glycoprotein1 (aβ2GP1) IgM and IgG was performed.ResultsThirty‐two (10.1%) HIV‐uninfected and 15 (13.2%) HIV‐infected participants were positive at baseline for one of the five criteria aPL, with no statistically significant difference. The profile of the HIV‐infected participants with thrombosis (n = 11) included LAC in 15.8%, aCL IgG in 3.5% and aβ2GP1 IgG in 1.8%. In contrast, the HIV‐infected controls (n = 4), included aCL IgM in 1.8% and aβ2GP1 IgM in 5.3%. Only LAC was significantly associated with thrombosis (p < 0.003). On repeat testing, in a HIV‐infected sub‐population, 2/7 with thrombosis were positive, while 3/3 controls tested negative.ConclusionIn contrast to earlier reports, the prevalence and expression of aPL in HIV‐infected women with a history of thrombosis in the present study, in the era of antiretroviral therapy, were similar to HIV‐uninfected women. Baseline LAC positivity was associated with a significantly increased risk for thrombosis in HIV. Future studies are recommended to explore additional coagulation abnormalities in HIV.
The risk factors of the postoperative poor wound healing in spinal tuberculosis patients: A single centre retrospective cohort study
Authors: Jiang Guanyin , Zhu Yong , Zhang Muzi , Qin Wanyuan , Xiong Tuotuo , Ou Yunsheng 
Published: February 2022

AbstractThe purpose of this study is to find out the risk factors of poor wound healing (PWH) in spinal tuberculosis (STB) patients. A total of 232 STB patients who underwent debridement surgery between January 2012 to June 2020 were included in this retrospective study. The study cohort was divided into two groups according to the presence or absence of PWH. The clinical characteristics of STB patients who developed PWH were evaluated, and risk factors were found using logistic regression analysis. Of the 232 patients, 30 developed PWH. Multivariate binary logistic regression analysis showed that pulmonary tuberculosis, long operation time and low postoperative albumin level were independent risk factors for PWH in STB patients. Receiver operating characteristic curve analysis showed that the optimal cutoff value of PWH in operation time and postoperative albumin are 200 minutes and 30 g/L, respectively. Pulmonary tuberculosis, long operation time and low postoperative albumin level are independent risk factors for PWH following surgery for STB. Curing pulmonary tuberculosis, controlling operation time and supervising postoperative serum albumin may decrease the risk of PWH among STB patients.
Thermal imaging for assessment of maize water stress and yield prediction under drought conditions
Authors: Pradawet Chukiat , Khongdee Nuttapon , Pansak Wanwisa , Spreer Wolfram , Hilger Thomas , Cadisch Georg 
Published: February 2022

AbstractMaize production in Thailand is increasingly suffering from drought periods along the cropping season. This creates the need for rapid and accurate methods to detect crop water stress to prevent yield loss. The study was, therefore, conducted to improve the efficacy of thermal imaging for assessing maize water stress and yield prediction. The experiment was carried out under controlled and field conditions in Phitsanulok, Thailand. Five treatments were applied, including (T1) fully irrigated treatment with 100% of crop water requirement (CWR) as control; (T2) early stress with 50% of CWR from 20 days after sowing (DAS) until anthesis and subsequent rewatering; (T3) sustained deficit at 50% of CWR from 20 DAS until harvest; (T4) late stress with 100% of CWR until anthesis and 50% of CWR after anthesis until harvest; (T5) late stress with 100% of CWR until anthesis and no irrigation after anthesis. Canopy temperature (FLIR), crop growth and soil moisture were measured at 5‐day‐intervals. Under controlled conditions, early water stress significantly reduced maize growth and yield. Water deficit after anthesis had no significant effect. A new combination of wet/dry sponge type reference surfaces was used for the determination of the Crop Water Stress Index (CWSI). There was a strong relationship between CWSI and stomatal conductance (R² = 0.90), with a CWSI of 0.35 being correlated to a 64%‐yield loss. Assessing CWSI at 55 DAS, that is, at tasseling, under greenhouse conditions corresponded best to the final maize yield. This linear regression model validated well in both maize lowland (R² = 0.94) and maize upland fields (R² = 0.97) under the prevailing variety, soil and climate conditions. The results demonstrate that, using improved standardized references and data acquisition protocols, thermal imaging CWSI monitoring according to critical phenological stages enables yield prediction under drought stress.
Composition and microstructure of Na0.5Bi0.5TiO3 ceramics with excess Bi
Authors: Dunce Marija , Birks Eriks , Antonova Maija , Bikse Liga , Kundzins Karlis , Freimanis Otto , Livins Maris , Dutkevica Sanija , Sternberg Andris 
Published: February 2022

AbstractIn the present work, Na0.5Bi0.5TiO3 (NBT) ceramics with the addition of excess Bi in two different ways – before calcination and before sintering – are considered, revealing how the excess Bi affects their microstructure and chemical content. Average grain size is seen to decrease, with the grain size distribution becoming less diffused at higher excess Bi concentrations. The reason for such a feature is the shift of the sintering temperature region where the abnormal grain growth starts to contribute towards higher temperatures. The influence of excess Bi is more pronounced in the case if it is added before calcination. It was discovered that a small amount of excess Bi helps to prevent the formation of Bi‐deficient inclusions. While, high concentrations of excess Bi induce the formation of Bi‐rich inclusions – most probably Na0.5Bi4.5Ti4O15. Possible mechanisms of formation of both types of inclusions are discussed in detail. Instead of Bi over‐stoichiometry, elevated Na content and slightly lower O content were detected in the matrix grains of the sintered NBT ceramics prepared with excess Bi. These deviations increase upon increasing the added excess Bi concentration. The presence of another, Na‐rich phase, is assumed, which could not be detected by X‐ray diffraction or by energy‐dispersive X‐ray analysis.
The degree of mucosal atrophy is associated with post‐endoscopic submucosal dissection bleeding in early gastric cancer
Authors: Hayashi Yoshito , Hatta Waku , Tsuji Yosuke , Yoshio Toshiyuki , Yabuuchi Yohei , Hoteya Shu , Tsuji Shigetsugu , Nagami Yasuaki , Hikichi Takuto , Kobayashi Masakuni , Morita Yoshinori , Sumiyoshi Tetsuya , Iguchi Mikitaka , Tomida Hideomi , Inoue Takuya , Mikami Tatsuya , Hasatani Kenkei , Nishikawa Jun , Matsumura Tomoaki , Nebiki Hiroko , Nakamatsu Dai , Ohnita Ken , Suzuki Haruhisa , Ueyama Hiroya , Sugimoto Mitsushige , Yamaguchi Shinjiro , Michida Tomoki , Yada Tomoyuki , Asahina Yoshiro , Narasaka Toshiaki , Kuribayashi Shiko , Kiyotoki Shu , Mabe Katsuhiro , Miyake Akimitsu , Fujishiro Mitsuhiro , Masamune Atsushi , Takehara Tetsuo 
Published: February 2022

AbstractBackground and AimDespite the widespread use of endoscopic submucosal dissection (ESD) for early gastric cancer, post‐ESD bleeding remains a significant problem. Intragastric pH plays an important role in intragastric bleeding. Because gastric acid secretion contributes to intragastric pH, both the presence or absence of Helicobacter pylori infection and the degree of gastric mucosal atrophy may affect bleeding. The present study aimed to clarify the relationship between post‐ESD bleeding and the degree of gastric mucosal atrophy based on H. pylori infection status.MethodsWe included 8170 patients who underwent ESD for early gastric cancer at 33 hospitals in Japan from November 2013 to October 2016. We analyzed the risk factors contributing to post‐ESD bleeding.ResultsThere were 3935 H. pylori‐positive patients and 4235 H. pylori‐negative patients. A nonsevere degree of gastric mucosal atrophy was an independent risk factor for post‐ESD bleeding in H. pylori‐negative patients (odds ratio: 1.51, P = 0.007), but not in H. pylori‐positive patients (odds ratio: 0.91, P = 0.600). Further, in H. pylori‐negative, but not H. pylori‐positive, patients, the rate of post‐ESD bleeding increased in a stepwise manner for patients continuing antithrombotic drug use, patients who withdrew antithrombotic drug use, and antithrombotic drug nonusers.ConclusionsNonsevere gastric mucosal atrophy was a risk factor for post‐ESD bleeding in early gastric cancer in H. pylori‐negative patients but not in H. pylori‐positive patients.
The Georgia Memory Net: Implementation of a statewide program to diagnose and treat Alzheimer's disease and related dementias
Authors: Bender Alexis A. , McIntosh Rebecca L. , Sudduth Sean , Harris Michaela , Tuckey Kathy , Morgan John C. , Jungerman Joanna M. , Cox Abby , Moore Miranda A. , Ingram Bryshia , Pier Ellyn , Johnson Theodore M. , Loring David W. , Hepburn Kenneth , Medders Laura , Levey Allan I. , Lah James J. , Hales Chadwick M. 
Published: February 2022

AbstractObjectivesThe number of people living with dementia is growing and most patients go years without receiving a specific diagnosis or support services, leading to suboptimal care, negative impacts on the quality of life, and increased costs of care. To address these gaps, the State of Georgia Department of Human Services collaborated with academic and community partners to create the Georgia Memory Net (GMN).DesignGMN is a hub and spoke model partnered with Emory University's Cognitive Neurology Clinic and Emory Goizueta Alzheimer's Disease Research Center to provide training and support for best practices in diagnosis and management to Memory Assessment Clinics (MACs) throughout the state.SettingCommunities across the State of Georgia.ParticipantsGMN is a mix of academic and community providers, hospital systems, state and community agencies. Patients and families are evaluated at the MACs and connected to community services.InterventionA dedicated clinic workflow: primary care providers (PCPs) identify a memory problem and refer to the MACs for diagnostic evaluation; meeting with a community services educator, and development of a care plan. The patient is reconnected with the PCP for continuity of care.MeasurementsInitial metrics include numbers of unique patients, total patient visits, and referrals to state agency partners for community services.ResultsGMN established five MACs across Georgia with annual state funding. Partners at Emory University provided initial training; refined patient workflows for best practices; and provide ongoing support, guidance, and continuing education for MAC teams. Local PCPs and community services partners demonstrated strong engagement with the new model.ConclusionsGMN is an innovative care model to improve access to accurate and timely diagnosis in patients with memory loss. GMN may help improve the quality of life for patients and families through preventive and early care.
Gene flow from rhesus (Macaca mulatta) to cynomolgus macaques (M. fascicularis) and effects of introgressive hybridization on reproduction in two biomedically relevant non‐human primate species
Authors: Kumpai Prangmas , Hamada Yuzuru , Kanthaswamy Sree , Malaivijitnond Suchinda 
Published: February 2022

AbstractBackgroundWe compared the reproductive patterns of wild Indochinese and Sundaic cynomolgus macaques (Mf) exhibiting different levels of genetic admixture with rhesus macaques (Mm).MethodsTen adult females from each Indochinese (WHM) and Sundaic (KN/KTK) Mf populations, which exhibited 50% and 15% of Mm autosomal SNPs, were selected as focal animals. Animals were observed for 12 months, and the frequencies of sexual proceptivity, attractivity and receptivity, number of newborns, and changes in sex skin were recorded.ResultsBoth populations showed all three sexual behaviors throughout the year, but they were classified as moderately seasonal breeders because their 3‐month birth counts were as high as ~50%. The fecundity of WHM was lower than the KN/KTK. Changes in sex skin of WHM were more prone to Mm's pattern than the KN/KTK.ConclusionThe introgressive gene flow from Mm to Mf does not affect Mf's sexual behaviors; however, it can impact fecundity and physiological (sex skin) changes.
Morphological correspondence between brain and endocranial surfaces in mice exposed to undernutrition during development
Authors: Bonfili Noelia , Barbeito‐Andrés Jimena , Bernal Valeria , Hallgrímsson Benedikt , Gonzalez Paula N. 
Published: February 2022

AbstractThe morphological changes of the brain and the skull are highly integrated as a result of shared developmental pathways and different types of interactions between them. Shared developmental trajectories between these two structures might be influenced by genetic and environmental factors. Although the effect of environmental factors on neural and craniofacial traits has been extensively studied, less is known about the specific impact of stressful conditions on the coordinated variation between these structures. Here, we test the effect of early nutrient restriction on morphological correspondence between the brain and the endocast. For this purpose, mice exposed to protein or calorie‐protein restriction during gestation and lactation were compared with a control group in which dams were fed standard food ad libitum. High‐resolution images were obtained after weaning to describe brain and endocranial morphology. By magnetic resonance imaging (MRI), brain volumes were obtained and endocasts were segmented from skull reconstructions derived from micro‐computed tomography (microCT). Brain and endocranial volumes were compared to assess the correspondence in size. Shape changes were analyzed using a set of landmarks and semilandmarks on 3D surfaces. Results indicated that brain volume is relatively less affected by undernutrition during development than endocast volume. Shape covariation between the brain and the endocast was found to be quite singular for protein‐restricted animals. Procrustes distances were larger between the brain and the endocast of the same specimens than between brains or endocasts of different animals, which means that the greatest similarity is by type of structure and suggests that the use of the endocast as a direct proxy of the brain at this intraspecific scale could have some limitations. In the same line, patterns of brain shape asymmetry were not directly estimated from endocranial surfaces. In sum, our findings indicate that morphological variation and association between the brain and the endocast is modulated by environmental factors and support the idea that head morphogenesis results from complex processes that are sensitive to the pervasive influence of nutrient intake.
Revisiting the role of melatonin in human melanocyte physiology: A skin context perspective
Authors: Sevilla Alec , Chéret Jérémy , Slominski Radomir M. , Slominski Andrzej T. , Paus Ralf 
Published: February 2022

AbstractThe evolutionarily ancient methoxyindoleamine, melatonin, has long perplexed investigators by its versatility of functions and mechanisms of action, which include the regulation of vertebrate pigmentation. Although first discovered through its potent skin‐lightening effects in amphibians, melatonin's role in human skin and hair follicle pigmentation and its impact on melanocyte physiology remain unclear. Synthesizing our limited current understanding of this role, we specifically examine its impact on melanogenesis, oxidative biology, mitochondrial function, melanocyte senescence, and pigmentation‐related clock gene activity, with emphasis on human skin, yet without ignoring instructive pointers from nonhuman species. Given the strict dependence of melanocyte functions on the epithelial microenvironment, we underscore that melanocyte responses to melatonin are best interrogated in a physiological tissue context. Current evidence suggests that melatonin and some of its metabolites inhibit both, melanogenesis (via reducing tyrosinase activity) and melanocyte proliferation by stimulating melatonin membrane receptors (MT1, MT2). We discuss whether putative melanogenesis‐inhibitory effects of melatonin may occur via activation of Nrf2‐mediated PI3K/AKT signaling, estrogen receptor‐mediated and/or melanocortin‐1 receptor‐ and cAMP‐dependent signaling, and/or via melatonin‐regulated changes in peripheral clock genes that regulate human melanogenesis, namelyBmal1andPer1. Melatonin and its metabolites also accumulate in melanocytes where they exert net cyto‐ and senescence‐protective as well as antioxidative effects by operating as free radical scavengers, stimulating the synthesis and activity of ROS scavenging enzymes and other antioxidants, promoting DNA repair, and enhancing mitochondrial function. We argue that it is clinically and biologically important to definitively clarify whether melanocyte cell culture‐based observations translate into melatonin‐induced pigmentary changes in a physiological tissue context, that is, in human epidermis and hair follicles ex vivo, and are confirmed by clinical trial results. After defining major open questions in this field, we close by suggesting how to begin answering them in clinically relevant, currently available preclinical in situ research models.