bluuebunny/crossref_metadata_2025_split huggingface dataset:
ISOLASI DAN ANALISIS ASAM LEMAK Scenedesmus quadricauda YANG DIISOLASI DARI AIR KOLAM
Authors: Susanty Devy 
Published: January 2022

Isolation and Fatty Acid Analysis of Scenedesmus quadricauda from freshwaterMicroalgae have fast growth rate and fatty acids which potential as bioenergy. In addition, microalgae are also living with binding carbon dioxide for photosynthesis, so as to reduce air pollution. In this study, samples were taken from the freshwater, Sawahan, Padang, West Sumatra. Nile red staining performed on the samples to see the potential of lipid content. Microalgae having lipid content were isolated using the capillary pipette technique then it was identified using a microscope. Isolated microalgae was identified as Scenedesmus quadricauda. Microalgae growth measured by optical density value. It cultivated in different concentrations of NaNO3 to see the effect of the amount of nitrogen on the growth. Scenedesmus quadricauda grew well at a concentration of 0.5 g / L NaNO3. Fatty acid analysis was done by using GC-MS. Scenedesmus quadricauda had several types of fatty acids. The most abundant fatty acid in Scenedesmus quadricaudawas C18: 1.Keywords: Microalgae, Scenedesmus quadricauda, Nile red staining, Isolation, Fatty acid ABSTRAKMikroalga memiliki laju pertumbuhan yang cepat dan mengandung asam lemak sehingga berpotensi sebagai bioenergi. Selain itu, mikroalga juga hidup dengan mengikat karbondioksia untuk proses fotosintesis, sehingga mampu mengurangi pencemaran udara. Pada penelitian ini, sampel mikroalga diambil dari air kolam dari daerah Sawahan, Padang, Sumatera Barat. Pewarnaan nilered dilakukan terhadap sampel untuk melihat potensi kandungan lipid. Mikroalga yang memiliki kandungan lipid diisolasi dengan menggunakan teknik pipet kapiler, kemudian isolat diidentifikasi secara morfologi dengan menggunakan mikroskop. Isolat yang diperoleh diidentifikasi sebagai Scenedesmus quadricauda. Isolat dikultivasi dalam Bold Bassal Medium (BBM). Pertumbuhan mikroalga diukur dengan melihat nilai optical density. Isolat dikultivasi dalam berbagai konsentrasi NaNO3 untuk melihat pengaruh jumlah nitrogen terhadap pertumbuhannya. Scenedesmus quadricauda tumbuh dengan baik pada konsentrasi 0,5 g/L NaNO3. Analisa asam lemak dilakukan dengan menggunakan GC-MS. Pada Scenedesmus quadricauda ditemukan beberapa jenis asam lemak. Asam lemak yang paling banyak terkandung pada mikroalga ini yaitu C18:1.Kata kunci: Mikroalga, Scenedesmus quadricauda, Pewarnaan nile red, Isolasi, Asam lemak
UJI SIFAT FISIKA-KIMIA DAN IDENTIFIKASI FENIL ETIL ALKOHOL MINYAK ATSIRI BUNGA MAWAR HASIL EKSTRAKSI PELARUT
Authors: Malasari Nur , Sutamihardja RTM , Syawaalz Amry 
Published: January 2022

Test of Physical and chemical Properties and Identification of Phenyl Ethyl Alcohol of Essential Oil Roses from Solvent ExtractionThe technology of extraction of roses oil currently is developed in small scale industries through distillation. However, this technology has many disadvantages. To overcome these obstacles, it is necessary to do research by using solvent extraction vapor (solvent extraction).This study was conducted to determine the type of solvent and the right ratio of solvent to obtain the highest "concrete" and "absolute" yields on the extraction of roses. The solvents chosen in this study were n-hexane, petroleum ether and ethanol with a ratio of 1: 3, 1: 4 and 1: 5 w / v. The 1: 5 w / v n-hexane solvent was the right solvent for extracting roses with the highest "concrete" and "absolute" yield levels for the perfume making of 0.85% and 0.07%. The main chemical component of rose essential oil detected by KGSM is phenyl ethyl alcohol with the highest phenyl ethyl alcohol content found in "absolute" of 1: 4 w / v n-hexane extraction of 6.53%.Keywords: Rose Flower, Essential Oil, Ekstraksi pelarutABSTRAK Teknologi ekstraksi minyak bunga mawar saat ini yang berkembang pada industri skala kecil yaitu penyulingan. Namun, teknologi ini memiliki banyak kelemahan. Untuk mengatasi kendala tersebut, maka perlu dilakukan penelitian dengan menggunakan ekstraksi pelarut mudah menguap (solvent extraction). Penelitian ini dilakukan untuk mengetahui jenis pelarut dan perbandingan pelarut yang tepat untuk memperoleh rendemen “concrete” dan “absolut” tertinggi pada hasil ekstraksi bunga mawar. Pelarut yang dipilih pada penelitian ini adalah n-heksana, petroleum eter dan etanol dengan perbandingan 1:3, 1:4 dan 1:5 b/v. Pelarut n-heksana 1:5 b/v adalah pelarut yang tepat untuk mengekstraksi bunga mawar dengan kadar rendemen “concrete” dan “absolut” tertinggi untuk pembuatan parfum sebesar 0,85 % dan 0,07%. Komponen kimia utama minyak atsiri bunga mawar yang terdeteksi oleh KGSM adalah fenil etil alkohol dengan kadar fenil etil alkohol tertinggi terdapat pada “absolut” hasil ekstraksi n-heksana 1:4 b/v sebanyak 6,53%.Kata kunci: Bunga Mawar, Minyak Atsiri, Solvent Extraction
Robust Pharmacodynamic Effect of LY3202626, a Central Nervous System Penetrant, Low Dose BACE1 Inhibitor, in Humans and Nonclinical Species
Authors: Willis Brian A. , Lowe Stephen L. , Monk Scott A. , Cocke Patrick J. , Aluise Christopher D. , Boggs Leonard N. , Borders Anthony R. , Brier Richard A. , Dean Robert A. , Green Steven J. , James Douglas E. , Jhee Stanford S. , Lin Qun , Lo Albert C. , May Patrick C. , Watson Brian M. , Winneroski Leonard L. , Yang Zhixiang , Zimmer Jennifer A. , McKinzie David L. , Mergott Dustin J. 
Published: January 2022

Background: The development of beta-site amyloid-beta precursor protein cleaving enzyme (BACE) 1 inhibitors for the treatment of Alzheimer’s disease requires optimization of inhibitor potency, selectivity, and brain penetration. Moreover, there is a need for low-dose compounds since liver toxicity was found with some BACE inhibitors. Objective: To determine whether the high in vitro potency and robust pharmacodynamic effect of the BACE inhibitor LY3202626 observed in nonclinical species translated to humans. Methods: The effect of LY3202626 versus vehicle on amyloid-β (Aβ) levels was evaluated in a series of in vitro assays, as well as in in vivo and multi-part clinical pharmacology studies. Aβ levels were measured using analytical biochemistry assays in brain, plasma, and cerebrospinal fluid (CSF) of mice, dogs and humans. Nonclinical data were analyzed using an ANOVA followed by Tukey’s post hoc test and clinical data used summary statistics. Results: LY3202626 exhibited significant human BACE1 inhibition, with an IC50 of 0.615±0.101 nM in a fluorescence resonance energy transfer assay and an EC50 of 0.275±0.176 nM for lowering Aβ1–40 and 0.228±0.244 nM for Aβ1–42 in PDAPP neuronal cultures. In dogs, CSF Aβ1hboxx concentrations were significantly reduced by ∼80% at 9 hours following a 1.5 mg/kg dose. In humans, CSF Aβ1–42 was reduced by 73.1±7.96 % following administration of 6 mg QD. LY3202626 was found to freely cross the blood-brain barrier in dogs and humans. Conclusion: LY3202626 is a potent BACE1 inhibitor with high blood-brain barrier permeability. The favorable safety and pharmacokinetic/pharmacodynamic profile of LY3202626 supports further clinical development.
Kinesiotaping for the treatment of haematomas in haemophiliacs: a case control study
Authors: Letizia Mauro Giulia 
Published: January 2022

Dalila Scaturro, Fabio Vitagliani, Mariasanta Napolitano, Gianluigi Pasta, GIUSEPPINA PASSANTINO, Fausto Arcuri, Sergio Siragusa, Michele Vecchio, Giulia Letizia Mauro

_Introduction_: Intramuscular hemorrhages are the second most common type of bleeding in patients with haemophilia. In haemophilic patients, muscle bleeding causes pain and postural defects and requires a long healing time.

_Aim: _The purpose of this study is to evaluate the effectiveness of kinesiotaping, in combination with functional rehabilitation and CO2 laser therapy, in the healing process of MH in patients with haemophilia.

_Methods:_ We recruited 39 haemophilia patients who presented with a muscle hematoma. The patients were divided into 2 groups: treatment group treated with kinesiotaping, functional re-education and CO2 laser therapy; and a control group treated with functional re-education and CO2 laser therapy. The evolution of the hematoma was studied ultrasonographically and some evaluation scales (NRS, FISH) were administered.

_Results:_ The treatment group, compared to the control group, showed significant improvements in terms of: hematoma diameter (2,36 ± 3,32 vs 6,47 ± 3,37; p <0,05), hematoma thickness (0,08 ± 0,12 vs 0,28 ± 0,14; p =0,08), pain (NRS: 2 ± 1,57 vs 3,53 ± 1,37; p <0,05) and number of days of replacement therapy (n° days: 1,3 ± 0,48 vs 3,2 ± 0,98; p <0,05). These results were shown to be superior in patients on prophylaxis.

_Conclusions: _Kinesiotaping, associated with therapeutic exercise and physical therapy, can be a valuable aid in reducing the healing times of muscle hematomas in haemophilic patients, especially if already under prophylaxis.
The impact of innovations on the efficiency of animal husbandry in Lviv region
Authors: Hirniak K. 
Published: January 2022

Domestic agricultural enterprises do not have a high level of innovation activity, however, stable and competitive operation of an agricultural enterprise is impossible without its innovative activity. Stabilization of the situation in the agricultural sector with the current level of competition and constant technological variables, the innovative vector of development is the driving component of economic growth. Activation of innovation of domestic agricultural enterprises is one of the important prerequisites for stability and sustainable socio-economic development of the country. Consequently, the effective functioning of the livestock industry is possible only under the conditions of systemic and purposeful innovation aimed at finding a variety of new opportunities provided by the business environment. The innovation process in domestic animal husbandry is clearly aimed at the end result - a certain socio-economic, technical or environmental effects. The efficiency of animal husbandry is determined after the introduction of innovation, calculated by the method of evaluation of investment projects. On the example of Lviv region we analyzed the conditions of innovative activity in animal husbandry, assessed the modern innovative potential of the industry, established the features of its innovation and investment activities. SWOT-analysis is an important component of assessing the position of livestock enterprises in the region. It should be recognized that the innovative activity of livestock enterprises is mainly associated with the final stage of the innovation process – the development of innovations. In 2020, farms of all categories of Lviv region compared to 2019 decreased meat production (sales for slaughter of farm animals in live weight) by 1.6 %, milk – by 4.7 %, eggs – by 0.3 %. cattle on farms of all categories on January 1, 2021 amounted to 144.4 thousand heads (including cows – 86.2 thousand heads), pigs – 346.1 thousand heads, poultry – 10.5 million. heads. Compared to January 1, 2020, the number of poultry increased by 5.7 %, pigs – by 4.1 %, the number of cattle decreased by 8.2 % (including cows – by 8.6 %). Innovative activity of the livestock industry is formed under the influence of the domestic innovation system and has its own specifics, which is caused by the peculiarities of agriculture. Most innovative projects are aimed at introducing innovations that contribute to the intensification of animal husbandry and increase the competitiveness of products. Thus, on the basis of innovative development of animal husbandry it is possible to achieve a significant increase in the competitiveness of agricultural enterprises, which will allow Ukrainian producers to achieve significant results in world markets for agricultural products.
Consisting and prospects of self-sufficiency level increase of the main livestock products in Ukraine
Authors: Maksym V. , Chemerys V. , Dushka V. 
Published: January 2022

The state food security near-term depends on the balanced development of agriculture on the whole and separate directions of agrarian business, which produce raw material and prepared food for providing necessities of internal market consumption. The agri-food subcomplex of Ukraine is characterized strengthening disadvantages between a plant-grower and livestock. More resources particular branch are concentrated on the production of agricultural cultures of feed and technical value, considerable volume of which Ukraine export for the necessities of other countries, forgetting about needs and possibilities of domestic AIC. In the article conducted analysis of self-sufficiency level on the basic types of livestock products in Ukraine that taking into account influence on forming of national food security. A statement of meat and meat products analysis is conducted after basic kinds, eggs, milk and dairy products in Ukraine during 2018–2019 years. Certainly level of self-sufficiency on the basic livestock products in Ukraine, and also taking into account the rational norms of consumption. It is set as a result of research, that the greatest level of self-sufficiency of the poultry farming products, namely by poultry meat and eggs – 126 %. A production of pig meat volume in Ukraine does not provide the annual fund of consumption, which is compensated thorough import in a volume over 100 thousand ton during 2019 year. Level of self-sufficiency and other types of meat pork, does not exceed 88 %. Deepening of the crisis phenomena is observed in the cattle breeding which is characterized rapid reduction of cows, in particular in the households through low purchase prices on milk and difficult social and demographic processes. Although a production of milk, beef and veal, volume in Ukraine answers the necessities of internal market development, however through annual reduction of cows head in a long-term prospect there will be a deficit of the cattle breeding products, which will be provided through import deliveries that negatively will influence on the state food security. With the purpose of strengthening the food security in Ukraine it is necessary to inculcate the system of measures financial, organizational, economic and technological direction.
Atributos físicos de um Latossolo sob sistemas de uso e manejo no médio Vale do Paraíba Paulista
Authors: Ribeiro Julio César , Almeida Julio Cesar Raposo de , Almeida Ana Aparecida Da Silva , Gadioli João Luiz , Pereira Marcos Gervasio 
Published: January 2022

Os atributos físicos do solo são indicadores indispensáveis na avaliação de diferentes sistemas de uso e manejo do solo. Objetivou-se, nesse trabalho, avaliar o efeito dos sistemas de uso e manejo i) pupunha para produção de frutos e sementes, ii) pupunha para produção de palmito, e iii) pastagem de Urochloa decumbens em pousio, em profundidade sobre os atributos físicos de um Latossolo Vermelho-Amarelo localizado no médio Vale do Paraíba Paulista, SP, Brasil. Em cada sistema foi determinada a resistência do solo à penetração nas profundidades de 0,00-0,10, 0,10-0,20 e 0,20-0,40 m, nas quais foram coletadas amostras para a determinação do teor de matéria orgânica, densidade do solo e de partículas e umidade (conteúdo de água) no solo. A condutividade hidráulica, densidade de partículas, porosidade e volume de saturação foram determinadas por meio da coleta de amostras nas profundidades de 0,00-0,10 e 0,40-0,50 m. Verificou-se que não houve diferença para os atributos densidade de partículas, densidade do solo, porosidade total, resistência à penetração e matéria orgânica entre os sistemas de uso e manejo avaliados. Contudo, a condutividade hidráulica e o conteúdo de água (umidade) no solo foram maiores na área de pastagem de Urochloa decumbens em pousio. Os parâmetros densidade do solo, resistência à penetração e matéria orgânica apresentaram maiores valores em menor profundidade, enquanto a porosidade total, conteúdo de água (umidade) e condutividade hidráulica apontaram menores valores. A densidade de partículas e volume de saturação não foram influenciadas significativamente em profundidade.
Individualism and collectivism in advertising – An overview
Authors: PHAM TAM 
Published: January 2022

Advertising is increasingly important in every corner of the world. It has become an indispensable part for both producers and consumers in modern society to boost the production and consumption of the products. To succeed in advertising, one component advertisers cannot ignore is cultural values because they are one of the determinants of customers’ behavior. Of the cultural dimensions, individualism and collectivism are considered the most important one. This study, therefore, sets the light on an overview of how individualism and collectivism is manifested in advertising in term of advertising themes, advertising creative tactics and linguistic advertising features in empirical studies. It then specifies what have and has not been done on the topic alike so that anyone interested in the field will find the gaps for their future research.
El potencial de la energía fotovoltaica como fuente de electricidad en Manabí
Authors: Navas Bayona Walter Iván , Durango Espinoza Rayner Stalyn , Landívar Chávez Edgar Fabricio 
Published: January 2022

Introducción. El cambio climático se mantiene como uno de los principales factores de riesgo para la humanidad, su efecto en las condiciones de vida y actividades de todos los seres vivos puede repercutir en forma drástica en el estilo de vida de los ecosistemas actuales. Diferentes países han implementado políticas y acciones que buscan mitigar el efecto de los gases invernadero y su contribución al cambio climático. El Ecuador ha implementado políticas para disminuir la emisión de gases contaminantes, modificando su matriz energética para aprovechar las condiciones climáticas y geográficas de la misma, buscando implementar el uso de energías renovables como la fotovoltaica. Objetivo. Analizar el potencial de generación eléctrica que se puede alcanzar en la provincia de Manabí, en el uso y aprovechamiento de la energía solar fotovoltaica. Metodología. Los datos se han obtenido por medio del uso de diferentes bases de datos de sistemas de energía solar, tomando valores de varias décadas referentes a la insolación solar, considerando como muestra los principales cantones de la provincia de Manabí; en donde se estimó los valores de generación de energía eléctrica que se puede alcanzar en cada cantón. Resultados. Los cantones de Manta y Montecristi alcanzan un alto nivel radiación solar superior a los 1,700 KWh/m2/año; Portoviejo y Jipijapa alcanzan valor superior a 1,600 KWh/m2/año, Chone y El Carmen valores ligeramente inferiores. Generando por metro cuadro con paneles de Silicio entre 205 a 262 KWh/año. Conclusión. La provincia de Manabí por su posición geográfica y sus condiciones climáticas muestra un alto potencial de desarrollo de energía de autoconsumo por medio de sistemas fotovoltaicos, lo cual permite plantear la viabilidad técnica de instalar sistemas fotovoltaicos a nivel de industrias, comercios y viviendas.
Pelatihan Pembuatan Preparat Segar Biologi Untuk Meningkatkan Keterampilan Guru dan Siswa di SMA Negeri 1 Argamakmur, Kabupaten Bengkulu Utara
Authors: Wibowo Risky Hadi , Sipriyadi Sipriyadi , Fatimatuzzahra Fatimatuzzahra , Wahyuni Reza , Setiawan Redo , Prastika Annisa , Rizawati Rizawati 
Published: January 2022

Biologimerupakan cabangilmu sains yangmempelajaritentangmahlukhidupbaik secaramikroskopishinggamakroskopisseperti hewan,tumbuhan,jamur,bakteri,virus,manusia, dan protista. Untuk meningkatkanmutu pengajaran di bidangbiologiperlupeningkatan keterampilan dalam bekerjadilaboratoriumatauyangseringdisebutdenganpraktikum.Pelaksanaankegiatanpengabdiankepadamasyarakat pada pelatihan pembuatan preparat segar yangdiikuti peserta sebanyak 20 siswa/i dan 5 orang guruSMANegeri1Argamakmur,BengkuluUtaradiawalidengantahappersiapan,kemudiansosialisasipemberianmateripengabdiankepadapesertapengabdian dengan pengenalan dan manfaatpembuatanpreparat,praktekpembuatanpreparat segaryang menghasilkan5jenis preparatyangdiamatidi bawah mikroskop binokuler yaitupreparateritrosit (darah merah) manusia,selakar bawang, sel epitel mukosa pipi, sel bakteri danhifapadajamur tempe.Kegiatanpengabdianinidiharapkandapat memberi pemahaman dan meningkatkan skill paragurubiologidansiswa-siswidalam membuat preparatyangakandimanfaatkandalamprosesbelajarmengajar (KBM) padakegiatanpraktikum pelajaranbiologidiLaboratorium
JUDICIAL ANALYSIS ON THE POSITION OF LEGAL OPINION (FATWA) OF INDONESIAN COUNCIL OF ULAMA’ (MUI) IN STATUTORY REGULATION SYSTEM OF INDONESIA
Authors: Pofrizal Pofrizal , Muslih Akhmad , Ardilafiza Ardilafiza 
Published: January 2022

The purpose of this research is to investigate, understand, describe, analyze and get a picture of the legal position of MUI fatwas in the statutory regulation system in Indonesia based on Law No. 12 of 2011 on Making Rules and Hierarchy of Rules. The method used in this research is normative. The results show that MUI fatwas are not included in positive law and don't have permanent legal power based on Law No. 15 of 2019 on the Amendment to Law Number 12 of 2011 on Making Rules and Hierarchy of Rules, so it cannot be legally applied to all Indonesian people. Also, fatwas of MUI cannot be a legal instrument to enforce legal act or to become the basis for imposing criminal sanctions for those who violate the law. It can only become positive law if the substance is stipulated by the authorized state institutions into laws and regulations as it is outlined in Law No. 15 of 2019 on the Amendment to Law No.12 of 2011 on Making Rules and Hierarchy of Rules.
Absenteísmo de usuários como fator de desperdício nas diferentes modalidades de gestão na saúde
Authors: Beltrame Sônia Maria , Oliveira Adauto Emmerich , Siqueira Carlos Eduardo , Santos Neto Edson Theodoro  dos 
Published: January 2022

O absenteísmo de usuários é considerado um problema crônico mundial na assistência à saúde, tanto no setor público como no privado, levando ao desperdício de recursos. O objetivo do presente estudo foi estimar a taxa e o desperdício de recursos monetários vinculados ao absenteísmo de usuários em consultas e exames especializados, nas diferentes modalidades de gestão no Sistema Único de Saúde (SUS), na Região de Saúde Metropolitana do Espírito Santo (RSM-ES), nos anos de 2014 a 2016. Foram analisados 1.002.719 procedimentos, sendo 666.182 consultas e 336.537 exames agendados nos 38 locais executantes, sendo 07 da administração direta e 31 da indireta. Os dados foram dos registros administrativos do Sistema de Regulação do Estado do Espírito Santo (SISREG-ES). Os valores monetários foram obtidos usando a Tabela SUS, tabela complementar de convênios e tabela de custos estimados, segundo o tipo de prestador. Para consultas, foram encontradas as maiores taxas e valores desperdiçados com o absenteísmo, no serviço privado 42,7% (R$ 2.000,00) e no público 39,1% (R$2.255.320,00). Para exames, no filantrópico 34,9% (4.459.951,03) e no público com gestão OSS 32,4% (R$8.943.943,26). A quantidade de estabelecimentos, a produção e o volume de recursos ofertados pelo SUS para exames especializados se concentram na administração indireta, tendo o setor filantrópico e o público com gestão de OSS como principais provedores. As taxas e os valores desperdiçados nas diferentes modalidades de gestão evidenciam o desafio na agenda dos gestores do SUS para garantir a integralidade da atenção.