bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of durability of knowledge transfer through reminiscence on the moral sensitivity of nurses
Authors: Bahrieni Farideh , Azodi Parviz , Hajivandi Abdollah , seddighi Zahra , Jahanpour Faezeh 
Published: November 2022

Abstract
Background
Nursing is a moral attempt and endeavor. Moral sensitivity training is one of the most important ways to strengthen nursing moral decision making. Thus, the purpose of this study was to determine the effect of durability of knowledge transfer through reminiscence on nurses’ moral sensitivity.

Methods
The present study is a controlled randomized clinical trial conducted in pre- and post- interventional forms. The research population consisted of all nurses working at Bushehr Persian Gulf martyrs training hospital in 2017, 68 nurses participated as samples in the study selected by available sampling method and then randomly assigned to two groups of intervention and control groups. In this study, Morphological Sensitivity Questionnaire of Lautzen was used. Validity and reliability of the questionnaire have been confirmed. The pre-test was obtained from the control and intervention group. An 8-hour reminiscence training session was held for the intervention group. In order to study, the durability of training, posttest was obtained from both groups. Data were analyzed by SPSS software version 19 and using t-test, Chi-square, paired t-test.

Results
The mean moral sensitivity score in nurses before intervention in both groups was not statistically different (P = 0.42). The comparison of the mean scores of nurses’ moral sensitivity after intervention in the control and intervention groups, which in fact, indicates the durability of education, showed a significant difference. (P < 0.001).

Conclusion
The results of this study showed that the transfer of knowledge and education through reminiscence has a lasting effect on enhancing the moral sensitivity of nurses. Therefore, its inclusion in nursing educational programs as a training strategy can be considered as a step toward facilitating the training of nurses’ moral sensitivity.

Trial registration
This study is registered by Iranian Registry of Clinical Trials with decree code: IRCT2016021612830N18 on May 17, 2017. This study adheres to the CONSORT 2010 statement guidelines.
Participatory development of practical, affordable, insecticide-treated mosquito proofing for a range of housing designs in rural southern Tanzania
Authors: Msoffe Rogath , Hewitt Matilda , Masalu John P. , Finda Marcelina , Kavishe Deogratius R. , Okumu Fredros O. , Mpolya Emmanuel A. , Kaindoa Emmanuel W. , Killeen Gerry F. 
Published: November 2022

AbstractBackgroundInsecticidal mosquito-proof netting screens could combine the best features of insecticide-treated nets (ITNs) and indoor residual spraying (IRS), the two most important front line vector control interventions in Africa today, and also overcome the most important limitations of these methods. This study engaged members of a rural Tanzanian community in developing and evaluating simple, affordable and scalable procedures for installing readily available screening materials on eave gaps and windows of their own houses, and then treating those screens with a widely used IRS formulation of the organophosphate insecticide pirimiphos-methyl (PM).MethodsA cohort of 54 households recruited upon consent, following which the structural features and occupant demographics of their houses were surveyed. Indoor mosquito densities were surveyed longitudinally, for approximately 3 months before and over 5 months after participatory house modification and screening using locally available materials. Each house was randomly assigned to one of three study arms: (1) No screens installed until the end of the study (negative control), (2) untreated screens installed, and (3) screened installed and then treated with PM, the insecticidal activity of which was subsequently assessed using standard cone assays.ResultsAlmost all (52) recruited households participated until the end, at which point all houses had been successfully screened. In most cases, screening was only installed after making enabling structural modifications that were accepted by the enrolled households. Compared to unscreened houses, houses with either treated or untreated screens both almost entirely excludedAnopheles arabiensis(Relative reduction (RR) ≥ 98%, P < < 0.0001), the most abundant local malaria vector. However, screens were far less effective againstCulex quinquefasciatus(RR ≤ 46%, P < < 0.0001), a non-malaria vector causing considerable biting nuisance, regardless of their treatment status. While PM did not augment household level protection by screens against either mosquito species (P = 0.676 and 0.831, respectively), 8 months after treatment it still caused 73% and 89% mortality among susceptible insectary-rearedAnopheles gambiaefollowing exposures of 3 and 30 min, respectively.ConclusionsParticipatory approaches to mosquito proofing houses may be acceptable and effective, and installed screens may be suitable targets for residual insecticide treatments.
High-flow nasal cannula versus non-invasive ventilation for acute hypercapnic respiratory failure in adults: a systematic review and meta-analysis of randomized trials
Authors: Ovtcharenko N. , Ho E. , Alhazzani W. , Cortegiani A. , Ergan B. , Scala R. , Sotgiu G. , Chaudhuri D. , Oczkowski S. , Lewis K. 
Published: November 2022

Abstract
Background
Non-invasive ventilation (NIV) with bi-level positive pressure ventilation is a first-line intervention for selected patients with acute hypercapnic respiratory failure. Compared to conventional oxygen therapy, NIV may reduce endotracheal intubation, death, and intensive care unit length of stay (LOS), but its use is often limited by patient tolerance and treatment failure. High-flow nasal cannula (HFNC) is a potential alternative treatment in this patient population and may be better tolerated.

Research question
For patients presenting with acute hypercapnic respiratory failure, is HFNC an effective alternative to NIV in reducing the need for intubation?

Methods
We searched EMBASE, MEDLINE, and the Cochrane library from database inception through to October 2021 for randomized clinical trials (RCT) of adults with acute hypercapnic respiratory failure assigned to receive HFNC or NIV. The Cochrane risk-of-bias tool for randomized trials was used to assess risk of bias. We calculated pooled relative risks (RR) for dichotomous outcomes and mean differences (MD) for continuous outcomes, with corresponding 95% confidence intervals (CI) using a random-effects model.

Results
We included eight RCTs (n = 528) in the final analysis. The use of HFNC compared to NIV did not reduce the risk of our primary outcome of mortality (RR 0.86, 95% CI 0.48–1.56, low certainty), or our secondary outcomes including endotracheal intubation (RR 0.80, 95% CI 0.46–1.39, low certainty), or hospital LOS (MD − 0.82 days, 95% CI − 1.83–0.20, high certainty). There was no difference in change in partial pressure of carbon dioxide between groups (MD − 1.87 mmHg, 95% CI − 5.34–1.60, moderate certainty).

Interpretation
The current body of evidence is limited in determining whether HFNC may be either superior, inferior, or equivalent to NIV for patients with acute hypercapnic respiratory failure given imprecision and study heterogeneity. Further studies are needed to better understand the effect of HFNC on this population.
Stress change generated by the 2019 İstanbul–Silivri earthquakes along the complex structure of the North Anatolian Fault in the Marmara Sea
Authors: Şahin Murat , Yaltırak Cenk , Bulut Fatih , Garagon Aslı 
Published: November 2022

AbstractThe North Anatolian Fault Zone is a dextral system operating between the Eurasian and Anatolian plates in northern Turkey. Across the Marmara Sea south of İstanbul, it deforms at ~18 mm/year slip rate, where the statistics of historical earthquakes suggest that a few M7+ earthquakes are generated every ~250 years. Currently, M7+ earthquakes are overdue as this section of the fault has not been reactivated since the 1766 and 1754 earthquakes. In this frame, identifying the stress change by the 2019 M5.8 İstanbul–Silivri earthquake is essential to characterize its influence on the critically stressed Marmara Sea segments of the North Anatolian Fault Zone. To do this, we mapped not only the main segments but also the secondary faults in the vicinity of the 2019 M5.8 İstanbul–Silivri earthquake to locate the fault patch it reactivated, as well as to accurately model the fault segments, where it significantly changed the stress. The joint analysis of relocated hypocenters and the Coulomb stress modeling shows that the mainshock failed a SW–NE striking splay fault, generating a stress increase of up to three bars on the fault that has the potential to generate M7+ earthquake.
Graphical Abstract
The conditional effect of family resilience on family quality of life during the Covid-19 pandemic
Authors: Setiawan Tery , Wardani Ria , Theresia Ellen 
Published: November 2022

Introduction This study examines how the Covid-19 economic impact and parental stress are moderated by family resilience to relate to the family quality of life (FQOL). Methods We modify the measure of FQOL, developed by Beach Center on Disability, by including only four domains (i.e., family interaction, parenting, emotional well-being, and material well-being) to adjust to our research context. Results Based on 169 participants, our CFA displays that all employed measures in the study are valid and reliable. Our regression analysis shows that there are significant direct relations of parental stress & family resilience with family quality of life. However, we find that family resilience only positively moderates the relation between the Covid-19 economic impact and family quality of life. Discussion This study presents a view on how the Covid-19 pandemic affects the way families live and hence, their quality of life.
Issue-networks as omitted publics in the construction of #rarediseaseday discourse
Authors: Hanchard Matthew 
Published: November 2022

Background: Over 450 million people worldwide have a rare disease. Yet despite healthcare policy rhetoric placing an onus on inclusive public engagement, rare disease publics are often engaged as data sources or product/service consumers. Meanwhile, various rare disease actors congregate around ‘Rare Disease Day’ each year – a global event with various online and offline talks, workshops, and sessions. In 2021, ~4.3 million tweets marked Twitter as a locus of exchange for the event. Methods: To examine public discourse around the event, the paper draws on social network and qualitative analyses of 40,366 Twitter tweets/retweets about rare disease day 2021 posted between 10-Feb-2021 and 10-Mar-2021, analysing them through a controversy theory lens. After identifying particularly influential Twitter users and groups, the paper examines their textual and visual communication strategies. Results: It funds three distinct orientations to rare disease discourse on Twitter (mission, awareness, and actor). In doing so, the paper locates a gap in direct engagement between medical authority and patients. Conclusions: It suggests that each orientation towards the discourse around rare disease day 2021 might be used by policymakers and researchers to engage with rare disease publics on social media in a more inclusive way as a pathway to better healthcare provision.
A Common Diagnosis Delayed by Three “Wrong Footing” Anchoring Errors – it is Difficult to Remember What You Have Forgotten
Authors: Kunitomo Kotaro , Shimizu Taro , Tsuiji Takahiro 
Published: November 2022

Very often in clinical practice, an inflamed pelvic appendix shows left lower quadrant abdominal pain as the primary painful area. The clinicians are anchored to the most prominent symptom, thereby taking an unnecessary detour in reaching an accurate diagnosis. A 40-year-old man presented to our emergency department with persistent lower left abdominal pain with a fever of 38 oC from a day earlier. He had a good appetite and repeatedly complained of severe constipation at the time of his visit. Physical examination revealed tenderness in the lower left abdomen without a peritoneal sign. Abdominal ultrasound and non-contrast-enhanced computed tomography revealed a left hydroureter. The next day, a radiologist pointed out the possibility of appendicitis. An urgent laparoscopic appendectomy was performed. The intriguing point of this case is the diagnostic delay because of three anchoring biases. First, the typical right lower abdominal pain of appendicitis was shielded by the intense left lower abdominal pain. Moreover, the presence of a left hydroureter distracted the physicians from the actual location of the pain. Furthermore, the presence of constipation anchored the physicians to constipation as the cause of abdominal pain. In overcoming these biases, specific diagnostic strategies to avoid biases should be implemented.
Extended local release and improved bacterial eradication by adding rifampicin to a biphasic ceramic carrier containing gentamicin or vancomycin
Authors: Sebastian Sujeesh , Tandberg Felix , Liu Yang , Raina Deepak B. , Tägil Magnus , Collin Mattias , Lidgren Lars 
Published: November 2022

AimsThere is a lack of biomaterial-based carriers for the local delivery of rifampicin (RIF), one of the cornerstone second defence antibiotics for bone infections. RIF is also known for causing rapid development of antibiotic resistance when given as monotherapy. This in vitro study evaluated a clinically used biphasic calcium sulphate/hydroxyapatite (CaS/HA) biomaterial as a carrier for dual delivery of RIF with vancomycin (VAN) or gentamicin (GEN).MethodsThe CaS/HA composites containing RIF/GEN/VAN, either alone or in combination, were first prepared and their injectability, setting time, and antibiotic elution profiles were assessed. Using a continuous disk diffusion assay, the antibacterial behaviour of the material was tested on both planktonic and biofilm-embedded forms of standard and clinical strains of Staphylococcus aureus for 28 days. Development of bacterial resistance to RIF was determined by exposing the biofilm-embedded bacteria continuously to released fractions of antibiotics from CaS/HA-antibiotic composites.ResultsFollowing the addition of RIF to CaS/HA-VAN/GEN, adequate injectability and setting of the CaS/HA composites were noted. Sustained release of RIF above the minimum inhibitory concentrations of S. aureus was observed until study endpoint (day 35). Only combinations of CaS/HA-VAN/GEN + RIF exhibited antibacterial and antibiofilm effects yielding no viable bacteria at study endpoint. The S. aureus strains developed resistance to RIF when biofilms were subjected to CaS/HA-RIF alone but not with CaS/HA-VAN/GEN + RIF.ConclusionOur in vitro results indicate that biphasic CaS/HA loaded with VAN or GEN could be used as a carrier for RIF for local delivery in clinically demanding bone infections. Cite this article: Bone Joint Res 2022;11(11):787–802.
ASSOCIAÇÃO ENTRE INFLAMAÇÃO E DIABETES MELLITUS EM HOMENS NA REGIÃO METROPOLITANA DE FEIRA DE SANTANA-BA
Authors: Dos Santos Erdes Blenda Maria , Claudia Fernandes de Almeida Oliveira  
Published: November 2022

O processo inflamatório crônico decorrente da hiperglicemia pode contribuir significativamente para complicações da doença em indivíduos diabéticos. (Lontchi-Yimagou, 2013). A disglicemia promove anormalidades metabólicas que favorece alterações genéticas, intracelulares e teciduais que contribuem para o desenvolvimento de um ambiente pró-inflamatório.
Changing Skill Formation in Greece and Italy – Crisis-Induced Reforms in Light of Common Institutional Legacies
Authors: Baumann Fabienne-Agnes , Vossiek Janis 
Published: November 2022

Context: After the Eurozone crisis unfolded a decade ago, comparative political economy has investigated reforms of public administration, labour market, welfare state and economic policy particularly in Southern European nations which were hit hardest by the crisis. However, analyses of skill formation reform, particularly vocational education and training (VET), have been scant, despite a common problem pressure for reforms emanating from stubbornly high rates of youth unemployment and similar legacies of statist VET. Approach: We investigate VET reforms brought underway in Greece and Italy during and in the aftermath of the crisis, asking how far apprenticeship-like forms of learning within their VET systems were strengthened. Empirically, we base our analysis on primary and secondary sources, having conducted semi-structured expert interviews in Greece and Italy in 2019. Results: We find that both countries attempted to strengthen the role of apprenticeship and work-based learning, but that politics differed across the two cases in the context of the Eurozone crisis. While in Italy, reforms were 'internalised' and shaped by domestic politics, Greek reforms were largely driven exogenously by the negotiations with the Troika. Conclusion: Although Italy and Greece have undertaken reforms to reduce the dominance of the state in VET provision by expanding apprenticeships and work-based learning, these do not amount to large scale changes to the dominant logic of school-based VET provision. In order to boost their potential in terms of practical learning both countries would need to continue on their reform pathways.
Protocol for iSISTAQUIT: Implementation phase of the supporting indigenous smokers to assist quitting project
Authors: Gould (Judean) Gillian Sandra , Kumar Ratika , Ryan Nicole M. , Stevenson Leah , Oldmeadow Christopher , La Hera Fuentes Gina , Deeming Simon , Hyland (Kamilaroi) Rebecca , Yuke (Yugambeh) Kym , McMillan (Wiradjuri) Faye , Oldenburg Brian , Clarke (Worimi) Marilyn J. 
Published: November 2022

IntroductionAbout 44% of Aboriginal and/or Torres Strait Islander women smoke during pregnancy compared to 12% of their general population counterparts. Evidence-based quit smoking advice received from health care professionals (HCPs) can increase smoking cessation rates. However, HCPs lack culturally appropriate smoking cessation training, which is a major barrier to provision of smoking cessation care for this population.Methods and analysisiSISTAQUIT is a multicentre, single arm study aiming to implement and evaluate the evidence-based, culturally competent iSISTAQUIT smoking cessation training among health practitioners who provide support and assistance to pregnant, Aboriginal and Torres Strait Islander women in Australia. This project will implement the iSISTAQUIT intervention in Aboriginal Medical Services and Mainstream Health Services. The proposed sample size is 10 of each of these services (total N = 20), however if the demand is higher, we will aim to accommodate up to 30 services for the training. Participating sites and their HCPs will have the option to choose one of the two iSISTAQUIT packages available: a) Evaluation- research package b) Training package (with or without continued professional development points). Training will be provided via an online eLearning platform that includes videos, text, interactive elements and a treatment manual. A social media campaign will be conducted from December 2021 to September 2022 to raise brand and issue awareness about smoking cessation for Aboriginal and Torres Strait Islander women in pregnancy. This national campaign will consist of systematic advertising and promotion of iSISTAQUIT and video messages through various social media platforms.AnalysisWe will use the RE-AIM framework (Reach, Effectiveness, Adoption, Implementation and Maintenance) to plan, evaluate and report the intervention impact of iSISTAQUIT. Effectiveness of social media campaign will be assessed via social media metrics, cross-sectional surveys, and interviews.DiscussionThis innovative research, using a multi-component intervention, aims to practically apply and integrate a highly translatable smoking cessation intervention in real-world primary care settings in Aboriginal Medical Services and Mainstream services. The research benefits Aboriginal women, babies and their family and community members through improved support for smoking cessation during pregnancy. The intervention is based on accepted Australian and international smoking cessation guidelines, developed and delivered in a culturally appropriate approach for Aboriginal communities.
Glycated hemoglobin level dynamics in COVID-19 survivors: 12 months follow-up study after discharge from hospital
Authors: Shestakova Marina , Kononenko Irina , Kalmykovа Zilya , Markova Tatyana , Kaplun Elena , Lysenko Mar’yana , Mokrysheva Natalya 
Published: November 2022

Introduction
One of the stages of reproduction of SARS-CoV-2 is the S-protein glycosylation to facilitate penetration into target cells. It has been suggested that SARS-CoV-2 is able to enter erythrocytes, interact with heme and porphyrin, which could influence HbA1c levels. Assessment of HbA1c levels in individuals with acute COVID-19 and after recovery may show clinical relevance of this hypothesis.

Aim
To assess HbA1c levels in patients with COVID-19 in the acute phase and in early (6–8 weeks) and late (52±2 weeks) periods after recovery.

Materials and methods
We conducted a multicenter prospective study, which included patients hospitalized in Endocrinology Research Centre and the City Clinical Hospital № 52" diagnosed with COVID-19, virus identified/ not identified. Patients were divided into three groups according to baseline HbA1c level and the presence or absence of previous history of diabetes previous history of diabetes mellitus (DM): HbA1c ≤ 6.0%, HbA1c > 6.0% and patients with DM. Patients were examined during the acute COVID-19 phase and in early (6–8 weeks) and late (52±2 weeks) periods after recovery. Oral glucose tolerance test was performed in the group with initial HbA1c > 6.0% to clarify the diagnosis.

Results
We included 194 patients in the study. During the follow-up, 52 patients were examined in 6–8 week period: 7 with HbA1c ≤ 6.0%, 34 with HbA1c > 6.0%, 11—with previously diagnosed DM. Carbohydrate metabolism assessment in the later stages (52±2 weeks) after recovery was performed in 78 patients: 33 patients with HbA1c ≤ 6.0%, 36 patients with HbA1c > 6.0% and 9 patients with previously established diabetes. HbA1c median in patients with HbA1c ≤ 6.0% was 5.7% [5.3;5.8], with HbA1c>6.0% -6.4% [6.2; 6.6], with previously diagnosed DM—7.7% [7.2; 8.9]. Statistically significant decrease in HbA1c over time 6–8 weeks after extracts were obtained in both groups of individuals without a history of DM (Wilcoxon test, p<0.05). After 52±2 weeks we observed HbA1c decrease in all three groups (Fridman test, p<0.05): in patients with HbA1c ≤ 6.0% median HbA1c was 5.5[5.3;5.7], with HbA1c>6.0% - 6.1[6.15;6.54], with previously diagnosed DM—7.8 [5.83; 8.08]. Development of DM after 52±2 weeks was recorded in 7.24% of all examined patients without a history of DM, which is 16.6% of the total number of patients examined in dynamics with HbA1c > 6.0%.

Conclusion
HbA1c elevation during the acute phase of COVID-19 may be false due to the effect of SARS-CoV-2 on hemoglobin kinetics and/or detection on the surface of the SARS-CoV-2 virion highly glycosylated S-proteins by high performance liquid chromatography determinations. Upon detection HbA1c > 6.0% in patients with COVID-19 in the active phase of the disease without concomitant hyperglycemia re-determine the level of HbA1c after recovery is recommended.