bluuebunny/crossref_metadata_2025_split huggingface dataset:
Student Perceptions of Teacher Support
Authors: Dolan Alyson Lavigne , Mccaslin Mary 
Published: February 2022

Background/Context Working theories about student goal orientation, understanding of intelligence, and affective mediation of task engagement inform current beliefs about students and learning and motivation. Much research has focused on identifying effective teaching strategies to raise the achievement of disadvantaged students; however, less is known about how students who attend high-poverty schools conceptualize school and teachers, and motivation and learning. Our study draws from literature on student motivation and learning to understand how students who attend Comprehensive School Reform (CSR) schools think about motivation and learning. Research Question We examined students’ responses to pictures of student-teacher interaction to understand how students who attend CSR schools think about motivation and learning. Story analysis was guided by the following questions: How do student stories portray student-teacher interaction? Specifically, what interpersonal supports and opportunities do they describe? What motivational systems are attributed to story characters? What are their challenges, behaviors, and goals? How do the story characters feel and manage their emotions? Population Students (N = 174) in Grades 3–5 who attended three CSR schools. Research Design Data collection consisted of student stories in response to a picture of student-teacher interaction. Project instruments and procedures are an adaptation of the Thematic Apperception Test (TAT). Conclusions Results suggest that students in these CSR schools held positive beliefs about their teachers and classroom learning. Story content analyses indicated that students’ perceptions of student-teacher interaction reflect a concern with achievement rather than affiliation. Achievement goals of story characters primarily concerned correctness; understanding and volitional engagement also were expressed. Story characters primarily were portrayed as compliant, optimistic, and relatively positive about their interaction with their teacher and their learning. In approximately one third of the narratives, story characters struggled with problems of varied magnitude; however, in half of these stories, characters were able to navigate solutions and overcome negative emotions and obstacles.
What We Learned about Research on School Reform: Considerations for Practice and Policy
Authors: Good Thomas L. , Mccaslin Mary 
Published: February 2022

Background/Context The U.S. federal government has been interested in improving the performance of students who come from low-income homes since the time of Lyndon Johnson's “Great Society” initiatives in the 1960s. The current administration strongly supports the belief that good schools can be created and has funded the Comprehensive School Reform (CSR) program to support these beliefs. This article provides information about recent school reform research and conditions of schooling. The article then reviews our research findings (drawing on all the preceding articles in the special issue) and considers implications for policy makers, principals, teachers, teacher educators, and researchers. Purpose The basic intent of this study was to inform working theories of learning, motivation, and social/emotional development in school contexts in Grades 3–5. We hoped that an emphasis on theory, contextual enactment, and participant mediation would yield a richer picture of classroom practices and motivational dynamics that might underlie student achievement and CSR effectiveness. This study focused in particular on perspectives (principals and students) and classroom practices associated with CSR programs in elementary schools in the state of Arizona. Research Design The research program includes interview (with principals), observation (of classroom practices), and survey measures, and an adaptation of Thematic Apperception Test procedures (with students). Conclusion/Recommendations School reform initiatives can profit from more research on participant perceptions, actual classroom practices, and student mediation of those practices. These understandings can better link program design and student achievement to enhance the effectiveness of CSR initiatives. We believe that it is now possible to conduct field experiments for improving normative (typical) practice in elementary school classrooms. We offer considerations for doing this research and suggest the need for attention to students, both as social beings and learners, while altering classroom practices in small measured steps.
Montessori and the Mainstream: A Century of Reform on the Margins
Authors: Whitescarver Keith , Cossentino Jacqueline 
Published: February 2022

Background/Context Montessori education has flourished as an alternative approach to schooling for a hundred years. In the century since the first Montessori school opened in the slums of Rome, the movement has undergone sustained growth while simultaneously enduring efforts to modify the method in order to reach a wider audience. Despite Montessori's endurance and reach, the movement remains largely unstudied by educational researchers. This article presents a historical treatment of the method and the movement by treating Montessori as a case study of enduring and ambitious educational reform. Purpose/Objective This article is an examination of the American Montessori movement as it has evolved over the course of the past one hundred years. Situated within an international context, the study traces the development of the movement from its failed introduction to the United States in 1991, to its rebirth in the 1960s, to its current resurgence as a time-tested alternative to conventional public schooling. Key questions revolve around Montessori's ongoing status as an influential yet marginal force in American educational reform. Research Design This is a historical case study drawn from archival data, interviews with Montessori leaders and practitioners, and secondary sources (biographies, memoirs) generated between 1906 and 2007.
Laryngopharyngeal Reflux: Evolution and Predictive Value of Symptoms and pH‐Impedance Features on Clinical Evolution
Authors: Lechien Jerome R. , Saussez Sven , Muls Vinciane , Dequanter Didier , De Marrez Lisa G. , Hans Stéphane , Rodriguez Alexandra , Lisan Quentin 
Published: February 2022

ObjectivesTo investigate the features of patients with laryngopharyngeal reflux (LPR) who did not respond to medical treatment.Study DesignProspective uncontrolled study.SettingMulticenter study.MethodsPatients with LPR at 24‐hour HEMII‐pH monitoring (hypopharyngeal‐esophageal multichannel intraluminal impedance–pH) were prospectively recruited from 3 European university centers. Patients were treated with 3‐ to 6‐month medication (proton pump inhibitor and alginate) and categorized as mild to moderate responders, high responders, or nonresponders according to Reflux Symptom Score (RSS) changes at 6 months posttreatment. The predictive value of the following outcomes was studied: epidemiologic data, HEMII‐pH, gastrointestinal endoscopy findings, baseline RSS and Reflux Sign Assessment, and early therapeutic response (6‐week RSS).ResultsA total of 148 patients completed the evaluations, accounting for 40 mild to moderate responders (20%‐60% RSS changes), 76 high responders (>60% RSS changes), and 32 nonresponders. Nonresponders presented more often with hiatal hernia and lower esophageal sphincter insufficiency when compared with mild to moderate and high responders (P =. 032). Baseline otolaryngologic, digestive, and respiratory RSS and the number of pharyngeal reflux events at the HEMII‐pH were predictive of the 6‐month therapeutic response (P <. 05). The early therapeutic response (6 weeks posttreatment) was predictive of the 6‐month treatment response.ConclusionHiatal hernia and baseline and 6‐week RSS were the most predictive indicators of therapeutic effectiveness in patients with LPR.
Comparative safety of chronic versus intermittent benzodiazepine prescribing in older adults: A population-based cohort study
Authors: Davies Simon JC , Rudoler David , de Oliveira Claire , Huang Anjie , Kurdyak Paul , Iaboni Andrea 
Published: February 2022

Background: Benzodiazepine treatment recommendations for older adults differ markedly between guidelines, especially their advice on the acceptability of long-term use. Aims: Using population-based data we compared risks associated with chronic versus intermittent benzodiazepine usage in older adults. The primary outcome was falls resulting in hospital/emergency department visits. Methods: We undertook a retrospective population-based cohort study using linked healthcare databases in adults aged ⩾ 66 years in Ontario, Canada, with a first prescription for benzodiazepines. Chronic and intermittent benzodiazepine users, based on the 180 days from index prescription, were matched (1:2 ratio) by sex, age and propensity score, then followed for up to 360 days. Hazard ratios (HRs) for outcomes were calculated from Cox regression models. Results: A total of 57,041 chronic and 113,839 matched intermittent users were included. Hospitalization/emergency department visits for falls occurred during follow up in 4.6% chronic versus 3.2% intermittent users (HR = 1.13, 95% confidence interval (CI): 1.08 to 1.19; p < 0.0001). There were significant excess risks in chronic users for most secondary outcomes: hip fractures, hospitalizations/emergency department visits, long-term care admission and death, but not wrist fractures. Adjustment for benzodiazepine dosage had minimal impact on HRs. Conclusion: Our study demonstrates evidence of significant excess risks associated with chronic benzodiazepine use compared to intermittent use. The excess risks may inform decision-making by older adults and clinicians about whether short- or long-term benzodiazepine use is a reasonable option for symptom management.
The neuropeptide cycloprolylglycine produces antidepressant-like effect and enhances BDNF gene expression in the mice cortex
Authors: Abdullina Aliya A , Vasileva Ekaterina V , Kulikova Elizabeth A , Naumenko Vladimir S , Plyusnina Alexandra V , Gudasheva Tatyana A , Kovalev Georgy I , Seredenin Sergei B 
Published: February 2022

Background: Cycloprolylglycine (CPG) is an endogenous dipeptide with a wide range of psychotropic activity and putative therapeutic potential for depression. A small but growing body of data suggests that antidepressant-like effect of CPG is associated with neuroplastic changes in the brain or 5-HT system modulation. However, the mechanisms of the dipeptide action remain elusive. Aims: Here, we characterize the effects of chronic CPG administration on behavior and genes expression of antidepressants sensitive catalepsy (ASC) mice strain, characterized by depressive-like behavior. Methods: ASC mice were injected with saline, fluoxetine (10 mg/kg/day), or CPG (1 and 2 mg/kg/day) during 2 weeks. Behavior was studied using the open field test, novel object test, elevated plus maze test, forced swim test, and tail suspension test (TST). The expressions of genes coding BDNF, CREB, 5-HT1A and 5-HT2A receptors, TPH2, and SERT in the brain were measured with quantitative real-time reverse transcription polymerase chain reaction (RT-PCR). Results: Chronic intraperitoneal administration of 1 and 2 mg/kg of CPG revealed the significant antidepressant-like effect by decreasing immobility time in the TST. At the same time, CPG did not negatively affect locomotor activity, cognition, or anxiety. In the real-time quantitative polymerase chain reaction (PCR) assay, chronic CPG treatment (2 mg/kg for 14 days) increased Bdnf mRNA level in the frontal cortex. Conclusions: Our findings extend the evidence for the effectiveness of CPG to reduce depressive-like behaviors. The antidepressant-like effect of CPG is mediated, as least in part, by BDNF-dependent mechanism. The exact mechanism remains to be elucidated, and further studies are warranted.
Development and validation of the Reward Deficiency Syndrome Questionnaire (RDSQ-29)
Authors: Kótyuk Eszter , Urbán Róbert , Hende Borbála , Richman Mara , Magi Anna , Király Orsolya , Barta Csaba , Griffiths Mark D , Potenza Marc N , Badgaiyan Rajendra D , Blum Kenneth , Demetrovics Zsolt 
Published: February 2022

Background: The reward deficiency syndrome (RDS) integrates psychological, neurological, and genetic factors of addictive, impulsive, and compulsive behaviors. However, to date, no instrument has been validated to assess the RDS construct. Aims: The present study developed and tested a tool to assess RDS. Methods: Data were collected on two college and university samples. Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were performed on Sample 1 ( N = 1726), and confirmatory analysis was conducted on an independent sample ( N = 253). Impulsivity and sensation-seeking were assessed. Results: Based on EFAs, a 29-item Reward Deficiency Syndrome Questionnaire (RDSQ-29) was developed, containing four subscales (lack of sexual satisfaction, activity, social concerns, and risk-seeking behavior). CFA indicated good fit (comparative fit index (CFI) = 0.941; Tucker–Lewis index (TLI) = 0.933; root mean square error of approximation (RMSEA) = 0.068). Construct validity analysis showed strong relationship between sensation-seeking and the RDS scale. Conclusion: The RDSQ-29 is an adequate scale assessing psychological and behavioral aspects of RDS. The RDSQ-29 assesses psychological and behavioral characteristics that may contribute to addictions generally.
Electroacupuncture suppresses spinal nerve ligation-induced neuropathic pain via regulation of synaptic plasticity through upregulation of basic fibroblast growth factor expression
Authors: Zhou Kecheng , Wu Qiaoyun , Yue Jingjing , Yu Xiaolan , Ying Xinwang , Chen Xiaolong , Zhou Ye , Yang Guanhu , Tu Wenzhan , Jiang Songhe 
Published: February 2022

Background: Improving synaptic plasticity is a good way to alleviate neuropathic pain. Electroacupuncture (EA) is currently used worldwide to treat this disease, but its specific mechanisms of action need further investigation. Evidence has suggested that basic fibroblast growth factor (bFGF) plays an important role in promoting nerve regeneration and can promote the expression of vascular endothelial growth factor (VEGF). Objective: In this study, we examined the effects of EA on synaptic plasticity and its underlying mechanism. Methods: A spinal nerve ligation (SNL) rat model was established. NSC37204 (a specific inhibitor of bFGF) was used to determine the relationship between bFGF and putative EA-mediated improvements in synaptic plasticity. Mechanical withdrawal threshold (MWT) and thermal withdrawal latency (TWL) were assessed to evaluate hyperalgesia in rats with SNL. Tissue morphology was detected by hematoxylin–eosin (HE) and Nissl staining, while neural plasticity and its molecular mechanisms were examined by Western blotting, quantitative real-time polymerase chain reaction (qPCR), dual-label immunohistochemistry and transmission electron microscopy. Results: We found that EA improved synaptic plasticity, consistent with higher levels of expression of bFGF and VEGF. Contrary to the beneficial effects of EA, NSC37204 promoted synaptic reconstruction. Furthermore, EA-induced improvements in the neurobehavioral state and improved synaptic plasticity were blocked by NSC37204, consistent with lower expression levels of bFGF and VEGF. Conclusion: These findings indicate that EA suppresses SNL-induced neuropathic pain by improving synaptic plasticity via upregulation of bFGF expression.
Knowledge-Intensive HRM Systems and Performance of Knowledge-Intensive Teams: Mediating Role of Team Knowledge Processes
Authors: Shahzad Khuram , Hong Ying , Jiang Yuan , Niaz Hina 
Published: February 2022

This study investigates whether and how knowledge-intensive HRM systems (KIHRS) impact the performance of knowledge-intensive teams (KITs). We integrate the ability-motivation-opportunity theory with the knowledge management literature to hypothesize that KIHRS affect KIT performance through team knowledge exploration and knowledge exploitation processes. A total of 543 responses (408 team members and 135 team leaders) from 135 KIT of 119 firms were collected in two waves with a time lag of 3 months. The findings indicate that KIHRS relate positively to KIT performance. Furthermore, team knowledge exploration and knowledge exploitation work in a sequence to mediate the relationship between KIHRS and KIT performance.
Retreatment with full-dose cytarabine in a patient with previous neurological toxicity
Authors: Casasnovas Núria Meca , Manzaneque Alba , Muntañola Ana , Castells Genís 
Published: February 2022

Introduction Cytarabine is one of the main chemotherapy drugs used to treat hematological malignancies. Neurotoxicity is an increasingly recognized adverse effect of high-dose cytarabine therapy and occurs in 10% to 25% of patients. There is very little experience with cytarabine retreatment following neurotoxicity. Case report We report a case of a man who was diagnosed with chemotherapy-induced cerebellar syndrome. He was treated with high doses of cytarabine. Management and outcome The patient was successfully retreated at full dose after experiencing cytarabine-induced cerebellar toxicity during the first cycle of a chemotherapy regimen. He did not develop any neurological complications and successfully underwent hematopoietic stem cell transplantation. He is currently in complete remission and free of disease. Discussion This original case report assesses the possibility of retreatment without the need for dose reduction.
Barriers and facilitators to delivering bystander cardiopulmonary resuscitation in deprived communities: a systematic review
Authors: Uny I , Angus K , Duncan E , Dobbie F 
Published: February 2022

Background: There is a higher incidence of cardiac arrest in economically deprived areas; however, data show that bystander cardiopulmonary resuscitation (CPR) in those areas is lower. This results in lower survival rates, placing those communities at a double disadvantage. This systematic review explored the barriers and facilitators to engaging with bystander CPR in deprived communities. Methods: Studies were eligible for inclusion if they addressed any barrier or facilitator to performing bystander CPR or being trained in CPR or training others. Studies had to either be set in a deprived area or examine a deprived population. Selected studies were published between January 2000 and December 2017 and reported on primary research. No language limitations were applied. Searches were conducted in the following databases: Cumulative Index to Nursing and Allied Health Literature (CINAHL), MEDLINE, PsycINFO, PubMed, and Web of Science Core Collection. Unpublished ‘grey’ literature was also searched as well as the reference lists of any relevant studies. Results: The systematic review highlighted several main factors acting as barriers or facilitators to engaging with bystander CPR in deprived communities: (1) the willingness to learn or perform CPR, (2) the confidence to perform CPR, and (3) self-reported likelihood of performing CPR. The review also revealed additional barriers to engaging with CPR which are specific to – or more acute for – individuals from socioeconomically deprived backgrounds or areas. Discussion: We found little evidence suggesting that the willingness to perform or learn bystander CPR is lower in deprived communities compared to the general population. However, the confidence to perform CPR in deprived communities was affected by some measures of socioeconomic status. The results also crucially highlighted other barriers more acute in deprived communities: the risk to personal safety in administering CPR; the fear of legal consequences; and the lack of community cohesion and other cultural barriers.
What is the Optimal Construct to Reduce Failure in Arthroscopic Four Anchor Rotator Cuff Repair?
Authors: Johnson Andrea H , West Michaline , Fowler M Brook , Petre Benjamin M , Turcotte Justin J , Redziniak Daniel E 
Published: February 2022

Background Re-tear following rotator cuff repair (RCR) is a concerning complication that can lead to poor patient outcomes and necessitate the need for revision surgery. The purpose of our study was to look at the combined construct of knotted vs. knotless medial row and suture vs. suture tape, focusing primarily on re-tear rates following surgery. Methods A retrospective observational study of 343 consecutive patients undergoing arthroscopic double row, 4-anchor rotator cuff repair from February 2014 to March 2020 was conducted. Univariate and multivariate statistics were used to assess differences in demographics, comorbidities and tear characteristics between patients who experienced a symptomatic re-tear and those who did not. Results The overall symptomatic re-tear rate was 7.6%. Patients who had a knotted medial row repair had a significantly lower rate of re-tear (4.7 vs. 11.3%, p = 0.022). Patients that had a knotted medial row and suture tape repair were significantly less likely to experience a re-tear (OR: 0.180, p = 0.001). Discussion The use of suture tape and a knotted medial row repair decreases the incidence of symptomatic re-tear following rotator cuff repair. The combined construct of suture tape and a knotted medial row in rotator cuff repair decreases the risk for symptomatic re-tear following surgery.
Patient-specific Instrumentation Versus Standard Surgical Instruments in Primary Reverse Total Shoulder Arthroplasty: A Retrospective Comparative Clinical Study
Authors: Elsheikh Ahmed A , Galhoum Mohamed S , Mokhtar Mohamed A , Roebuck Margaret M , Wood Amanda , Yin Qi , Frostick Simon P 
Published: February 2022

Aims Patient-specific instrumentation (PSI) in primary shoulder arthroplasty has been studied; results supported the positive impact of the PSI on the glenoid positioning. Nevertheless, no clinical outcomes have been reported. We compare the clinical outcomes of primary reverse total shoulder arthroplasty using PSI versus the standard methods. Methods Fifty-three patients with full records and a minimum of 24-months follow-up were reviewed, 35 patients received primary standard RSTA, and 18 patients received primary PSI RSTA. All patients were operated on in a single center. The median follow-up was 46 months (53 months in the standard group vs 39 months in the PSI group). Results There was an overall significant post-operative improvement in the whole cohort (P< 0.05). The standard group had more deformed glenoids (B2, B3, C&D) and significantly low preoperative constant score and forward flexion (P=0.02 & 0.034). Compared to the PSI group (all were A1, A2, B1 &one type D), there were no statistically significant differences in any clinical outcome postoperatively. PSI neither prolonged the waiting time to surgery (P=0.693) nor the intraoperative time (P=0.962). Radiologically, PSI secured a higher percentage of optimum baseplate position and screw anchorage; however, no statistical correlation was found. Conclusion In this series, both groups achieved comparable good outcomes. PSI did not achieve significantly better clinical outcomes than Standard after primary RSTA. Yet comparison has some limitations. PSI did not negatively impact the waiting time or the surgical time.