bluuebunny/crossref_metadata_2025_split huggingface dataset:
Growth Hormone Excess: Implications and Management
Authors: Dhaneshwar Suneela , Shandily Shrishti , Tiwari Vatsalya 
Published: October 2022

Abstract:
Acromegaly is described as the oversecretion of growth hormone (GH) and, subsequently,
insulin-like growth factor 1 (IGF-1), ascribed in most cases to a pituitary adenoma. This
disease presents a progressive disfigurement, along with other systemic manifestations, which altogether
diminishes the quality of life in the patients. Prolonged exposure to abnormally high levels
of GH and IGF-1 levels results in cardiovascular, cerebrovascular, and pulmonary dysfunction
which overall produces a fall in life expectancy. Timely diagnosis and further treatment decreased
the mortality rate of the patients and showed an improvement in the quality of life. Surgical procedures,
advanced radiation therapy tools, and the availability of pharmacological compounds that act
on pituitary growth hormone-producing cells have enabled an improved approach to treating the
disease. Pharmacological treatment is currently an important management option, and it may also
be the first-line treatment in patients with acromegaly who do not benefit from or are ineligible for
first-line surgical procedures. From its inception until 2021, we used a comprehensive search strategy
on Medline/PubMed, Scopus, Embase, Web of Science, and the Cochrane Library electronic
databases. All human research articles and review articles published in English were considered for
the review. In this review, we describe the clinical implications and management of patients with
acromegaly, consisting of scientific improvements underlying the developing understanding of
pathogenesis and diagnosis, associated comorbidities and mortality rate with the disease, and major
improvements in the treatment of the disease, along with novel strategies including quality of life
and patient-reported outcomes.
Smoking Status Association with Intention to Vaccination against Coronavirus Disease-2019
Authors: Al-Rawashdeh Sami , Mrayyan Majd T. , Hayajneh Audai A. 
Published: October 2022

Objectives:
This paper aimed to examine the association between smoking status and the intention to get the COVID-19 vaccine in a convenience sample of 226 Jordanian adults.

Methods:
Cross-sectional data on smoking status, the intention of vaccination, attitudes toward- and fear of COVID-19, and perceived susceptibility and severity of COVID-19 were collected. Descriptive comparative and correlational bivariate and multivariable statistical analyses were used.

Results:
Most subjects were female and single, with a mean age of 26.8 years. About 27.9% were smokers. Smokers had significantly higher mean scores on the intention of vaccination than non-smokers (p=.049). On regression analysis, smoking status was not a significant predictor, but higher scores on attitude toward and fear of COVID-19 were the only significant predictors of the intention for vaccination.

Conclusion:
Although smokers appear to have a higher intention to get the COVID-19 vaccine, variables other than smoking status, such as attitudes towards and fears of COVID-19 may influence people's decisions and should be appropriately addressed. Smoking's effect on the intention of vaccination with COVID-19 warrants further study.
The Role of Secondary Infections and Underlying Diseases in the Mortality of Patients with COVID-19
Authors: Mahmoudi Hassan 
Published: October 2022

Background:
Coronavirus disease (COVID-19) caused by coronavirus is a respiratory infection, that has spread worldwide in the past few months. Considering the necessity and importance of the COVID-19 pandemic, determining the importance of the secondary infection of COVID-19 patients and the death of these patients is one of the main issues considered in the study. Common bacterial infections are often found in viral respiratory infections and are major causes of death. This study investigated the cause of death from COVID-19 within a year.

Methods:
In this cross-sectional study from March 2020 and March 2021, 1600 patients with secondary infection were enrolled based on their characteristics, symptoms and signs, laboratory data and presence of other underlying diseases. Chi-square test analysis were used to check the effectiveness of other comorbidities on the mortality outcome among patients with COVID 19.

Results:
Of the 1,600 COVID 19 patients with secondary infection who have died, 900 (56.25%) had underlying diseases, such as 380 (42.22%) with COPD, 80 (8.89%) with cardiovascular disease and hypertension, 25 (2.78%) with Obesity and smoking, 265 (29.44%) with age over 60 years, 150 (16.67%) with diabetes. 700 (43.75%) patients had no underlying disease.

Conclusion:
The most important causes of death in COVID-19 patients were secondary infections caused by important nosocomial bacteria. High mortality rates in COVID-19 patients indicate the importance of secondary infections.
AL IHTILAF AL-FIQHI WA TAUDZIF FI QADHAYA MA`ASHIRA
Authors: Athambawa Mahroof 
Published: October 2022

This research Paper Studies the issue of "jurisprudence differences" and ways of Employing them in contemporary issues, which is an important issue in the present day, Because There are People such as Orientalists and Prejudiced who view the reality of jurisprudence differences as a gap that defects the structure of Islamic jurisprudence and then come to the conclusion that it is merely comprising a group of human thoughts and not a living revelation from Almighty God as it is believed ,However, the reality that should not be forgotten by the Thinker who is free from intellectual biased precedents, that the jurisprudential differences arising from the derivation of the scholars who had profound knowledge with the sincerity of religious commitment and Devotion to God is the Outcome of approach intended By Allah and used to Derive Islamic Judgments from the Quran and the Sunnah. Jurisprudential differences are a function established by the god for the scholars in order to take care of the interests of the people and fulfill their innate needs, but the question arises what are the best approaches to take advantage of this rich scientific heritage in our contemporary issues, this research provides a detailed treatment of this issue and lead to the results that can be utilized in the development of jurisprudential work in the present day.
TRANSMISSION OF ANTIPLURALISM IN THE MILLENNIAL DIGITAL MEDIA SPACE
Authors: Shaleh Shaleh , Ansyory Anhar , Putro Khamim Zarkasyih , Jandra Mifedwil 
Published: October 2022

Excessive religious attitudes have shown an increasing trend among young people in some research results. This research intends to examine the transmission of anti-pluralism in the digital media space of millennial youth. For this purpose, researchers used a qualitative case study method by collecting data through site observations used by millennials, searching for documents on digital media, and interviews with several youths, some of whom had been influenced by the doctrine of anti-pluralism. The results of this study indicated that adherents of anti-pluralism had transmitted this understanding in the digital space of millennials through hyperlinks between sites. These links are used to transform understandings, among others: anti-difference, sole ruler of truth, thaghut, anti-Pancasila, and revolution. This transmission was an effort to carry out clandestine regeneration with the young millennial generation who are the primary users of this media.
TRANSFORMATION ON THE MUSLIM WOMEN ROLE AND ITS IMPACT ON THE FAMILY RESILIENCE
Authors: Suripto Agus Suryo , Rofiq Ahmad , Jamil Muhsin 
Published: October 2022

Transformation on the women role can be considered as the process of developing the mankind civilization. In the past, the transformation of women had been more by the economic motive. Along with the turn of the century, the women roleÂ hasÂ not only been dominated by the economy-related motive and domain but has expanded to the domains that used to be occupied by men. As a result, such role transformation has brought certain impacts to the actors. With reference to the statement, the high figure of divorce law suit has been suspected as one of the impacts caused by the transformation. Therefore, through the review several efforts will be pursued in order to identify why, on the one hand, women have crippled the family resilience and, on the other hand, women have strengthened the family resilience. The results of the review show that the transformation on the women role have resulted in two different conditions within the family resilience. The vulnerability and the strength of the family resilience might at least be categorized into three dimensions namely the dimension of physical resilience, the dimension of social resilience, and the dimension of psychological resilience. In terms of physical resilience, both the vulnerable family and the strong family have relatively met their fundamental needs. On the contrary, there are differences in the other two dimensions namely the social resilience and the psychological resilience. In terms of social resilience, the vulnerable family and the strong family has displayed different quality on the aspects of conflict management, effective communication, and religious values. Similarly, in terms of psychological resilience the vulnerable family and the strong family has also displayed different quality on the aspects of positive self-concept, right and responsibility fulfilment satisfaction, family harmony maintenance, mutual respect and self-esteem, and compassion. The different quality on the dimension of social resilience and the dimension of psychological quality has resulted in the different end of the family life.
Rapid maxillary expansion vs slow maxillary expansion in patients with cleft lip and/or palate: a systematic review and meta-analysis
Authors: Luyten Jonathan , De Roo Noëmi M. C. , Christiaens Jeroen , Van Overberghe Leonie , Temmerman Liesbeth , De Pauw Guy A. M. 
Published: October 2022

ABSTRACT

Objectives
To compare the dentoalveolar outcomes of slow maxillary expansion (SME) and rapid maxillary expansion (RME) used for maxillary expansion before secondary alveolar bone grafting in patients with cleft lip and/or palate (CL/P). Secondarily, the advantages and disadvantages of SME vs RME were reviewed.

Materials and Methods
A systematic search was conducted up to November 2021, including Medline (via PubMed), Embase (via Ovid), Web of Science, Cochrane Central, and Google Scholar. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were followed. Risk-of-bias assessment was performed using the Risk of Bias (RoB 2.0) and Risk Of Bias In Non-randomized Studies of Interventions (ROBINS I) tool. Overall quality was assessed using the Grading of Recommendations Assessment, Development, and Evaluation tool.

Results
Of 4007 records, five studies met the inclusion criteria. The randomized control trial (RCT) had a low risk of bias, the non-RCTs presented with a moderate risk of bias. Arch width and perimeter increased significantly with both SME and RME treatments. No difference in the increase in palatal depth was found. The meta-analysis showed a greater anterior-to-posterior expansion ratio for the Quad Helix (QH) appliance. The results for dental tipping were not conclusive.

Conclusions
SME and RME promote equal posterior expansion in cleft patients. The anterior differential expansion is greater with SME (QH appliance). No clear evidence exists concerning the amount of dental adverse effects of SME and RME in cleft patients.
Comparison between orthodontic and surgical uprighting of mandibular molars: a systematic review
Authors: Karkazi Frantzeska , Karvelas Nikolaos , Alexiou Antigoni , Gizani Sotiria , Tsolakis Apostolos I. 
Published: October 2022

ABSTRACT

Objectives
To evaluate and compare the efficiency of orthodontic treatment and surgical uprighting of first and second mandibular molars.

Materials and Methods
An electronic literature search in PubMed, Science Direct, Embase, Scopus, Web of Science, Cochrane Library, LILACS, and Google Scholar, as well as a hand search was conducted by two independent researchers to identify relevant articles up to January 2022. In addition, a manual search was done that included article reference lists, grey literature, and dissertations. The risk of bias of the included prospective and retrospective studies was assessed with the Risk Of Bias Tool In Non-randomized Studies of Interventions (ROBINS-I) assessment tool.

Results
A total of six nonrandomized clinical trials (non-RCT) evaluating the efficiency of mandibular molar orthodontic and/or surgical uprighting were included. The quality analysis showed certain defects of the Non-RCTs included and, according to the criteria used, the majority of the articles were judged to be of moderate quality.

Conclusions
Based on the evidence, orthodontic and surgical uprighting appear to be effective treatment methods for mandibular molars. Surgical uprighting may be associated with more complications than orthodontic uprighting. However, the existing literature on the subject is limited, heterogeneous, and methodologically limited. Therefore, the outcomes should be interpreted carefully.
EFL Students’ Perceptions of the Effective English Teacher Characteristics
Authors: Tatipang Devilito Prasetyo , Manuas Maissy J. , Wuntu Ceisy Nita , Rorintulus Olga A. , Lengkoan Fergina 
Published: October 2022

This study aimed to analyze EFL students' perceptions of the characteristics of the English language teachers and find out whether there is any difference in the student perceptions of the characteristics of effective English teachers based on gender. This study is quantitative. The research design used in this study is the descriptive and comparative research design. The descriptive design was used because the purpose is to examine and describe the students' perceptions of the characteristics of effective English language teachers. The questionnaires also consist of the respondents' profiles such as gender and 24 modified items of questions regarding students' perceptions of the characteristics of effective English teachers. This study involved 120 respondents from grade 11 of science, social, and Language class. The results of this study showed that students' perceptions of the characteristics of effective English teachers were found to be high involvement since the mean score was 3.08. The result of this study also found that there was no significant difference in the EFL Students' perceptions of the characteristics of effective English teachers based on gender since the result got p= 0.018. Another result of this study found that socio-affective skills are the distinctive characteristic that teachers must have to call an effective English teacher since the mean score was 3.45.
Dificuldade do atendimento médico a pessoas com deficiência auditiva severa
Authors: Tavares Lorena Fecury , Cardoso Keise Bastos , Brito Caio Vinícius Botelho 
Published: October 2022

Objetivo: Analisar limitações e adaptações do atendimento médico aos pacientes com deficiência auditiva. Material e Métodos: Estudo analítico-descritivo, observacional, transversal e quantitativo. Foram entrevistados 50 professores médicos de uma Instituição de Ensino Superior (IES) que aceitaram fazer parte da pesquisa. Resultados: Observou-se que a maior parte tinha de 36 a 45 anos (38%), com média geral de 42,8 anos. Mais da metade era do sexo feminino (58%) e formou-se na graduação entre os anos de 1991 a 2010 (30 médicos, ou 60% do total). A maioria é formada em clínica médica (16%) e pediatria (12%) e 94% dos médicos já atenderam paciente com deficiência auditiva. O número de médicos que fizeram curso da Libras e se formaram entre 2011 e 2016 foi superior ao dos anos anteriores. Discussão: A maioria dos médicos sentiu-se desconfortável em atender um paciente com essa deficiência por desconhecimento da língua, sendo este um fator que encontra amparo na literatura. As instituições oferecem o curso ou uma disciplina de libras de formato opcional. Conclusão: A grande maioria dos médicos se sentiu desconfortável por não conseguir uma comunicação efetiva, apresentaram dificuldade em coletar anamnese e não faziam um receituário diferente, podendo comprometer a adesão ao tratamento. A maioria acredita que o aprendizado de Libras seria a solução, mas apenas quatro realizaram algum curso.
The Influence of Compatibility and Technology Acceptance Model Toward Intention to Use E-Wallet During Covid-19
Authors: Ramadhani Gilda Azalia Nur Ramadhani , Astuti Miguna , Nasirun Noraini 
Published: October 2022

Since Covid-19, cashless especially e-wallet has become a trend in Indonesia. This was caused by the compatibility between e-wallet with the Indonesian lifestyle primarily when the Covid-19 protocol was applied and also could be used for a continuous purpose. This research was done to analyze the impact of compatibility and the Technology Acceptance Model (TAM) on the intention to use e-wallets. The technology acceptance model (consisting of perceived ease of use, and perceived usefulness) is used to underpin the research framework. The data collected in this study are from college students who are living in Indonesia and using e-wallet. The measurement will be adapted from previous research in which the reliability and validity are confirmed using pre-testing. SPSS and SmartPLS are used to analyze the data. The output could become a contribution for the development of the TAM model in relation to the intention to use e-wallet among college students in Indonesia. In addition, the result could become an insight to understand consumer behaviors when using e-wallet.
Constructing legislative networks in R using incidentally and backbone
Authors: Neal Zachary P. 
Published: October 2022

Abstract
Political network data can often be challenging to collect and clean for analysis. This article demonstrates how the incidentally and backbone packages for R can be used together to construct networks among legislators in the US Congress. These networks can be customized to focus on a specific chamber (Senate or House of Representatives), session (2003 to present), legislation type (bills and resolutions), and policy area (32 topics). Four detailed examples with replicable code are presented to illustrate the types of networks and types of insights that can be obtained using these tools.
The Neutrophil-to-Lymphocyte Ratio’s Predictive Utility in Acute Pulmonary Embolism: Systematic Review
Authors: Arbănași Emil Marian , Mureșan Adrian Vasile , Arbănași Eliza Mihaela , Kaller Réka , Cojocaru Ioana Iulia , Coșarcă Cătălin Mircea , Russu Eliza 
Published: October 2022

Abstract
Acute pulmonary embolism is a cardiovascular emergency with a significant morbidity and mortality. In the last decade, attempts have been made to find prognostic markers for pulmonary embolism. We conducted a systematic review of the literature for studies that assess the relationship between the neutrophil-to-lymphocyte ratio (NLR) and disease progression in patients with pulmonary embolism. We included a total of seven studies published between 2016 and 2021, reporting on a total of 4,272 patients. The mean NLR observed in these studies was 5.93, with values ranging from 5.12 to 7.3. Elevated NLR was significantly associated with an increased rate of mortality in all studies. Furthermore, the collected data revealed a 2-to-15 times higher mortality rate in the group with NLR values higher than the mean. Due to its accessibility and the simplicity with which it can be calculated, as well as the outcomes revealed in this review, we strongly emphasize that NLR should be used more in medical practice.
Diagnostic and Treatment Algorithm in a Plurivascular Patient – Case Report
Authors: Magdás Annamária , Szász Zsuzsánna Ágnes , Kalapács Andrea Mária 
Published: October 2022

Abstract

Introduction: Atherosclerosis represents the main cause of arterial stenosis, mostly affecting the arteries of the lower extremities. Atherosclerotic arterial disease presents multiple localizations, including the carotid, subclavian, coronary, and kidney arteries. The severity of the stenosis does not always correlate with the symptomatology.

Case report: We present the case of a patient with multisite atherosclerotic disease. A 70-year-old smoker male patient, with a history of myocardial infarction and renal artery stenosis, presented in the emergency department complaining of vertigo, chest pain, and intermittent claudication. The diagnostic and treatment algorithm represented a challenge. Imaging assessment showed atherosclerotic lesions in a new vascular territory, which involved the left subclavian artery with a stenosis of 70%.

Conclusions: Subclavian artery stenosis can be a hidden form of atherosclerotic disease, often undiagnosed, which needs urgent interventional treatment and can be easily unmasked using simple tools such as measuring the blood pressure on both arms. Patients with athero-sclerotic lesions must undergo comprehensive screening for multisite atherosclerotic disease.
Integrated Assessment of Oregano (Origanum Vulgare L.) Accessions from the ex situ Collection of Genetic Resources
Authors: Sivicka Irina , Adamovičs Aleksandrs , Sokolova Olga , Lācis Gunārs , Krivmane Baiba 
Published: October 2022

Abstract
Oregano (Origanum vulgare L.) is one of the priority medicinal and aromatic plants in Europe because of its broad potential for use and distribution assessments of the species. The involvement of oregano genetic resources in cultivation can solve the problems of depletion of natural habitats and allows receiving high yield in marginal meteorological conditions. Also, ex situ conservation is the most applicable method for conserving local species of medicinal and aromatic plants in Nordic Europe. There is limited information about the characterisation and evaluation of oregano genetic resources in Latvia and Europe. In this study, long-term observations on 44 oregano accessions maintained at the ex situ collection of medicinal and aromatic plants of the Latvia University of Life Sciences and Technologies, were characterised by the Draft Descriptor List under the agro-climatic conditions of Latvia. Integrated assessment of oregano genetic resources was made to recommend the most valuable accessions for growing.
Evaluation of Apple Chlorotic Leaf Spot Virus Impact on Fruit Yield and Vegetative Growth in Apple Cultivars ‘Antonovka’ and ‘Gita’
Authors: Zuļģe Neda , Rubauskis Edgars , Missa Imants , Reveliòa Daina , Borisova Indra 
Published: October 2022

Abstract
The negative influence of pathogens on plant development is well known. However, the negative impact depends on various factors: cultivar and rootstock resistance, nutrition, the environment, the virulence, and concentration of pathogens in the plant tissue. The evaluation of apple chlorotic leaf spot virus (ACLSV) influence on apple tree growth and production was performed at Institute of Horticulture (LatHort) from 2012 to 2020. Virus-free and ACLSV-infected trees from the traditional cultivar ‘Antonovka’ and new scab resistant cultivar ‘Gita’ were evaluated on dwarfing rootstock B.396. The presence of four common apple viruses (apple mosaic virus (ApMV), ACLSV, apple stem grooving virus (ASGV), apple stem pitting virus (ASPV)) was assayed in the planting year and repeated at the end of the study period. The vigour of planting material, growth, yield, and yield efficiency were compared between virus negative and ACLSV-infected trees. During eight growing seasons (2013–2020), no statistically significant negative impact of ACLSV infection on tree growth or yield was observed for the cultivars. A larger canopy volume was observed for ACLSV-infected trees (p = 0.01), but the cumulative yield per canopy volume was equivalent between virus-negative trees and ACLSV-infected trees (p = 0.07).