bluuebunny/crossref_metadata_2025_split huggingface dataset:
Outcomes and Hand Use of Reaching Attempts: Comparison of Infants at Risk for Developmental Disability and Infants With Typical Development
Authors: Remec Nushka , Zhou Judy , Shida-Tokeshi Joanne , Pickering Trevor A. , Vanderbilt Douglas L. , Smith Beth A. 
Published: June 2022

BackgroundInfants at risk for developmental disabilities often show signs of motor delay. Reaching is a skill that can help us identify atypical motor trajectories in early infancy. Researchers have studied performance after onset of reaching, but none have followed infants at risk from pre-reaching to skilled reaching.AimsWe assessed differences in reaching outcomes and hand use as reaching skill emerged in infants at risk for developmental disabilities and with typical development.Methods and ProceduresWe followed infants at risk for developmental disabilities (n = 11) and infants with typical development (n = 21) longitudinally as they developed reaching skill. Infants reached for a toy at midline while sitting in the caregiver’s lap. Video data were coded for reach outcome (miss, touch, partial grasp, and whole-hand grasp) and hand use (right, left, and bilateral).Outcomes and ResultsInfants at risk had a larger proportion of missed reaches across visits compared to infants with typical development. Infants at risk also showed less variability in hand use when grasping over the study period.Conclusion and ImplicationsOur results provide information to support early differences in reaching performance to inform identification of typical and atypical developmental trajectories. Future studies should assess how the missed reaches are different and consider other quantitative measures of movement variability in infants at risk.
Dyadic Experiences and Psychosocial Management of Couples Facing Advanced Cancer: A Systematic Review of the Literature
Authors: Hasdenteufel Marie , Quintard Bruno 
Published: June 2022

BackgroundCancer diagnosis and treatment represent a real upheaval both for the patient and for his or her life partner. Adjustment to cancer has been widely studied at the individual level, however, there is little in the literature about the experiences of the couple as an entity. This is especially true with regard to a population facing advanced cancer. This systematic review aimed to make an inventory of 1) the current knowledge relating to the experience of the patient-partner dyad when confronted with advanced cancer, and 2) the psychosocial interventions specifically centered on this dyad.MethodThis review was conducted using the Cochrane methodology. The eligibility criteria for the literature review were: one of the members of the dyad being treated for advanced cancer, dyad composed of the patient and his/her life partner. Databases from PubMed, PsycArticle, PsycInfo, Psychology and Behavioral Sciences Collection and Scopus were investigated. A thematic content analysis on the basis of admitted articles made it possible to respond to each of our research objectives.ResultsThree hundred eighty-nine citations were found. Twenty were admitted to the systematic review of the literature. It highlighted the following experiences of the advanced cancer patient-life partner dyad: uncertainty about the future, disjointed time, intrusion into the couple's intimacy, attachment style and caregiving within the couple, couple's adjustment to cancer symptomatology, the couple's supportive care needs, role changes, nature of communication within the couple, anticipation of the coming death, and the meanings and beliefs around death. This review also describes the range of couple therapies used in the context of advanced cancer: emotionally focused-couple therapy, existential therapy, art therapy, support therapy and couple communication and intimacy promotion. These therapies seem to have individual beneficial effects for both the patient and his or her life partner as well as improving marital functioning.ConclusionsThese results clearly highlight that consideration of the couple and communication within the couple during care are fundamental to dyadic adjustment to advanced cancer. Further studies (qualitative and quantitative) are needed to better understand the couple's experience in order to adapt the management of the couple facing advanced cancer.
Hepcidin (rs10421768), Transferrin (rs3811647, rs1049296) and Transferrin Receptor 2 (rs7385804) Gene Polymorphism Might Be Associated with the Origin of Multiple Sclerosis
Authors: Stachowska Laura , Koziarska Dorota , Karakiewicz Beata , Kotwas Artur , Knyszyńska Anna , Folwarski Marcin , Dec Karolina , Stachowska Ewa , Hawryłkowicz Viktoria , Kulaszyńska Monika , Sołek-Pastuszka Joanna , Skonieczna-Żydecka Karolina 
Published: June 2022

Multiple sclerosis (MS) is a demyelinating disease of the central nervous system in which there is a multifocal damage to the nerve tissue. Additionally, the literature emphasizes the excessive accumulation of iron in the central nervous system of patients, which is negatively correlated with their psychophysical fitness. Iron metabolism genes polymorphisms may modulate iron deposition in the body and thus affect the clinical course of MS. We aimed to assess the frequency of HAMP, TFR2, and TF polymorphisms in MS patients and their impact on the clinical course of the disease. The studied polymorphisms were identified by the Real-Time PCR using TaqMan technology. Neurological assessment by means of EDSS scale was conducted. This cross-sectional study included 176 patients, with the mean age of onset of symptoms at 30.6 years. The frequency of alleles of the studied polymorphisms was as follows: (a) HAMP rs10421768: A 75.9% (n = 267), G 24.1% (n = 65), (b) TF rs1049296: C 89.2% (n = 314), T 10.8% (n = 38), (c) TF rs3811647: A 39.8% (n = 140), G 60.2% (n = 212), (d) TFR2 rs7385804: A 59.1% (n = 59.1%), C 40.9% (n = 144). In the codominant inheritance model of TF rs1049269, it was shown that people with the CT genotype scored statistically significantly lower points in the EDSS scale at the time of diagnosis than those with the CC genotype (CC Me = 1.5, CT Me = 1.0 p = 0.0236). In the recessive model of TF inheritance rs3811647, it was noticed that the primary relapses were significantly more frequent in patients with at least one G allele compared with those with the AA genotype (AG + GG = 81.2%, AA = 18.8%, p = 0.0354). In the overdominant model rs7385804 TFR2, it was shown that among patients with the AA genotype, multiple sclerosis occurs significantly more often in relatives in a straight line compared with people with the AC and CC genotypes (AA = 100.0%, AC + CC = 0.0%, p = 0.0437). We concluded that the studied polymorphisms might affect the clinical course of MS.
Novel Thiadiazole-Based Molecules as Promising Inhibitors of Black Fungi and Pathogenic Bacteria: In Vitro Antimicrobial Evaluation and Molecular Docking Studies
Authors: Rashdan Huda R. M. , Abdelrahman Mohamad T. , Shehadi Ihsan A. , El-Tanany Sara S. , Hemdan Bahaa A. 
Published: June 2022

Novel 1,3,4-thiadiazole derivatives were synthesized through the reaction of methyl 2-(4-hydroxy-3-methoxybenzylidene) hydrazine-1-carbodithioate and the appropriate hydrazonoyl halides in the presence of a few drops of diisopropylethylamine. The chemical structure of the newly fabricated compounds was inferred from their microanalytical and spectral data. With the increase in microbial diseases, fungi remain a devastating threat to human health because of the resistance of microorganisms to antifungal drugs. COVID-19-associated pulmonary aspergillosis (CAPA) and COVID-19-associated mucormycosis (CAM) have higher mortality rates in many populations. The present study aimed to find new antifungal agents using the disc diffusion method, and minimal inhibitory concentration (MIC) values were estimated by the microdilution assay. An in vitro experiment of six synthesized chemical compounds exhibited antifungal activity against Rhizopus oryzae; compounds with an imidazole moiety, such as the compound 7, were documented to have energetic antibacterial, antifungal properties. As a result of these findings, this research suggests that the synthesized compounds could be an excellent choice for controlling black fungus diseases. Furthermore, a molecular docking study was achieved on the synthesized compounds, of which compounds 2, 6, and 7 showed the best interactions with the selected protein targets.
UJI EFEKTIVITAS ATRAKTAN BERBAHAN HASIL FERMENTASI TERHADAP JUMLAH DAN DAYA TETAS TELUR NYAMUK AEDES AEGYPTI
Authors: Kurniawan Entuy , Dewi Novi Utami 
Published: June 2022

Pengendalian nyamuk Aedes aegypti sebagai vektor demam berdarah dengue (DBD) dapat dilakukan dengan penggunaan ovitrap yang dimodifikasi menjadi lethal ovitrap. Penambahan zat atraktan pada ovitrap dapat menarik lebih banyak nyamuk untuk datang ke perangkap yang dipasang dan mencegah nyamuk bertelur di tempat lain. Penelitian ini bertujuan untuk membandingkan sifat atraktan, persentase jumlah telur menetas dan mortalitas larva pada lethal ovitrap yang diberi tambahan dua jenis atraktan. Aktraktan yang digunakan adalah bahan hasil fermentasi yaitu tape ketan (Oryza sativa L var forma glutinosa) dan tape singkong (Manihot utillisima) yang juga memiliki potensi sebagai larvasida. Jenis penelitian adalah eksperimen dengan static group comparison. Sampel yang digunakan adalah nyamuk Aedes aegypti yang diperoleh dari hasil rearing telur nyamuk yang diperoleh dari Litbangkes Pangandaran. Larutan tape ketan dan tape singkong yang dibuat dalam berbagai konsentrasi melalui uji pendahuluan. Hasil penelitian menyatakan tape ketan memiliki sifat atraktan lebih tinggi dari tape singkong, semakin tinggi konsentrasi semakin tinggi jumlah telur yang tidak menetas. Kematian larva minimal 50% (LC50) pada ekstrak tape ketan 34.024% dengan rentang pada derajat kepercayaan 95% antara 33.194% sampai 35.938%. dan tape singkong sebesar 26.089% dengan rentang pada derajat kepercayaan 95% antara 21.394% sampai 29.293%. Direkomendasikan untuk studi lebih lanjut terhadap kandungan zat aktif pada bahan hasil fermentasinya dan aplikasi di lapangan sebagai upaya pengendalian vektor demam berdarah.
PENGARUH PENDIDIKAN KESEHATAN TERHADAP PERUBAHAN PERILAKU REMAJA PUTERI DALAM MENJAGA KEBERSIHAN GENITALIA EKSTERNA
Authors: Wardhani Sri Wisnu , Pramanik Novita Dewi 
Published: June 2022

Adolescent period is considered as a crucial period of life. There are a rapid physical growth spurt and mental development include the sexual organ maturity in this period. Therefore, healthy behaviors include cleanness of reproductive organ is important thing to know. The study aimed to find out the influence of health education on preserving external genital cleannes. fhis was a quasi experiment study with purposive sampling. There were two groups of female teenagers consist of 70 respondents totally. The study results revealed that health education was significantly influence respondents knowledge, attitude and behavior (p=0,000). ln the intervention group there were 60% respondents who had good level of knowledge; having positive attitude (97,1 %) and having good behavior 88,51%. In the control group, there were no changing of knowledge, attitude and behavior on the preserving external genital cleannes.
EFISIENSI INSTALASI PENGOLAHAN AIR LIMBAH (IPAL) PELAPISAN LOGAM PTDI DALAM MENURUNKAN KADAR CROM (CR6+)
Authors: Ruhmawati Tati , Roni S Tatang 
Published: June 2022

Levels of pollutants produced by PT DI after passing through wastewater are generally below the quality standard including chromium, but there are some parameters that exceed the standard quality including COD parameter. Although the levels of hexavalent chromium (Cr6+) below the quality standard, but should get attention, because of its accumulative can endanger the environment and health.The purpose of the study was to determine the efficiency of Waste Water Treatment Plant (WWTP) metal plating PT Dirgantara Indonesia (DI) in lowering levels of hexavalent chrome (Cr6+) and COD.
The study was quasi-experimental with one group pretest-posttest design. Population is wastewater generated from metal plating process of PT DI, the sample is part of waste water taken from the influents, chemical processing, and effluent. Sampling method is using grab sampling method (immediate sample), with sampling techniques for physical and chemical examination. Data processing was performed using SPSS soft ware. Data analysis using Paired samples T-test and one way anova.
At the influent concentration value is the same temperature of 25 0C, pH 12.7 to 13.8. Levels of hexavalent chromium (Cr6+) ranged between 1.03 mg/l to 2.10 mg/l. While the COD level ranged from 4336.64 mg/l to 4898.88 mg/l. In the process of temperature levels ranging from 25.5 0C to 26 0C, pH levels ranging from 4 to 5. While the COD level ranged from 3259.20 mg/l to 3900.00 mg/l. At the same effluent concentration value temperature of 25 0C, pH levels ranging from 7.1 to 7.3. Levels of hexavalent chromium (Cr6+) ranged between 0.01 mg/l to 0.40 mg/l. While the COD level ranged from 2400.00 mg/l to 3656.48 mg/l. After passing through the WWTP, the percentage decrease in levels of hexavalent chromium (Cr6+) ranged from 72.73% to 99.04% with an average decrease of 89.77%. Thus WWTP PT DI is efficient in reducing the levels of hexavalent chromium (Cr6+). Percentage reduction in COD level ranged from 16.91% to 44.66% with an average decrease of 30.62%. Thus WWTP PT DI has not been efficient in reducing the COD level.
No difference between the levels of hexavalent chromium (Cr6+) and COD in the influent and effluent. For hexavalent chromium (Cr6+) 0.002 p value less than 0.05, for the COD level of 0.003 p value less than 0.05. There was no significant difference between concentration and effluent COD in the process, with a p value of 0,056 is greater than 0,05
Sosialisasi Penggunaan Media Sosial dan Marketplace untuk Meningkatkan Penjualan Produk
Authors: Afdhal Muhammad , Prawiro Radius , Fenia Selvi Zola 
Published: June 2022

Macetnya pertumbuhan ekonomi, Pemutusan Tenaga Kerja (PHK), rasa takut keluar rumah serta menurunnya daya beli masyarakat menengah ke bawah membuat pelaku Usaha Mikro Kecil Menengah (UMKM) kesulitan mendapatkan pembeli. Tentu harus ada strategi yang tepat di tengah pandemi supaya UMKM tetap bisa menjual produknya dan mendapatkan keuntungan. Salah satu strategi di masa pandemi ialah marketplace yang memungkinkan pelaku UMKM dapat memasarkan produknya tanpa terkendala kebijakan-kebijakan selama pandemi. Kegiatan ini diikuti oleh 20 orang anggota UMKM Hobi Kayu Padang (HKP). Tujuan pelaksanaan program ini adalah mengedukasi Peserta UMKM HKP agar lebih mengikuti kemajuan teknologi informasi khususnya Sosial Marketplacdan memberikan strategi kepada peserta UMKM HKP dalam menggunakan teknologi dalam pengenalan/sosialisasi penggunaan Marketplace. Target dari kegiatan pengabdian kepada masyarakat ini adalah Peserta UMKM HKP, akan mengangkat kegiatan berbasis pengabdian kepada masyarakat berupa penggunaan Marketplace dalam pengembangan UMKM HKP. Hasil kegiatan PKM yang dilakukan dalam bentuk Sosialisasi Penggunaan Media Sosial Dan Marketplace Untuk Meningkatkan Penjualan Produk Bagi Umkm Komunitas HKP yaitu: Mampu Mengedukasi Peserta yaitu bapak dan Ibu Komunitas HKP dalam Penggunaan Media Sosial Dan Marketplace Untuk Meningkatkan Penjualan Produk, Membantu Komunitas HKP memahami kembali cara mengunakan media sosial dan marketplace dan masalah dapat diselesaikan khususnya dalam penjualan produk pada saat pandemi
KEJAHATAN SEKSUAL TERHADAP ANAK (PERSPEKTIF HUKUM INDONESIA)
Authors: Yunus Ahmad , Fathorrahman Fathorrahman 
Published: June 2022

Masa kanak-kanak adalah salah satu masa emas yang dialami oleh manusia. Dimana pada masa anak-anak ini jiwanya masih sangat bersih dan diharapkan jiwa yang bersih tersebut bisa diisi dengan hal-hal baik, pelajaran baik, pengalaman baik dan lain sebagainya yang sifatnya positif, dengan harapan manusia atau seseorang tersebut ketika sudah beranjak dewasa dia akan menjadi orang yang baik dan menebar kebaikan untuk lingkungannya. Karena pentingnya masa anak-anak, maka kita semua harus memberikan perhatian atau penjagaan ekstra terhadap anak-anak yang ada disekitar kita, terlebih jika anak tersebut adalah anak kita. Di era yang penuh kemajuan dan kebebasan saat ini, salah satu bahaya besar yang menjadi ancaman bagi anak adalah bahaya akan kejahatan seksual terhadap anak. Kejahatan seksual berdampak negatif terhadap anak, baik itu secara fisik maupun psikis, terlebih lagi kejahatan ini akan sangat mengganggu masa depan anak. Hal ini menjadi tanggung jawab kita bersama sebagai manusia sempurna, terlebih lagi pemerintah memiliki peran yang signifikan dalam melakukan perlindungan terhadap anak melalui aturan-aturan yang memberikan perhatian khusus terhadap anak. Dalam hal ini penulis akan membahas tentang perlindungan hukum terhadap anak sebgai korban kejahatan seksual dan bagaimana pertanggung jawaban pidana pelaku kejahatn seksual terhadap anak.
Pendampingan UMKM Berbasis Modul ILO Score di Toko Sembako Nadin Family Bengkayang Kalimantan Barat
Authors: Sugianto Helena Anggraeni Tjondro , Saputra Marko Ayas , Emeliana  
Published: June 2022

Toko sembako Nadin Family merupakan salah satu UMKM yang ada di Bengkayang. Toko Nadin Family berdiri pada tahun 2019. Ada beberapa permasalahan yang ada di UMKM toko Nadin Family diantaranya lingkungan area toko Nadin Family ini masih kurang bersih, belum ada sosial media, dan laporan keuangannya juga masih tercampur. Hal ini dikarenakan keterbatasan pemahaman dalam melakukan pengelolaan UMKM yang membuat pemilik toko kesulitan dalam mengelola toko. Oleh karena itu, diperlukan pemberdayaan UMKM melalui pendampingan guna untuk meningkatkan kesejahteraan UMKM yang ada di Kabupaten Bengkayang berdasarkan Modul ILO Score. Adapun tujuan dari pengabdian ini, adalah; 1) Memberikan pemahaman dan wawasan kepada Pemilik Toko Nadin Family terkait manajemen Berbasis Modul ILO Score, 2) Membuat promosi di Google Maps dengan mengunggah foto lokasi toko Nadin Family, 3) Merencanakan dan menerapkan modul 3K, dan 4) Memberi pelatihan tentang literasi keuangan maupun pembukuan dan penghitungan Harga Pokok Penjualan (HPP). Adapun metode yang digunakan dari modul ILO SCORE yaitu 5S, Promosi, K3 dan Literasi Keuangan. Hasil kegiatan telah berhasil menerapkan Modul 5S, Modul K3, Modul Promosi, Modul Pembukuan dan Penghitungan Harga Pokok Penjualan (HPP) bagi Toko Sembako Nadin Family Bengkayang.
Relationship Between Implementation of Discharge Planning and Patient Satisfaction Among Adult Inpatients
Authors: Kiki Ocktarianti , Istianah Istianah , Haryanto Mokh Sandi , Hutapea Albert Manggading 
Published: June 2022

Discharge Planning is a dynamic and systematic process for assessment, preparation, and coordination undertaken to facilitate and monitor health services before and after discharge. The objective of this study is to know the relationship between the implementation of discharge planning to patient satisfaction among adult inpatients. The analytical cross sectional approach was used through purposive sampling. The subjects of this research were 78 ward patients. Implementation of discharge planning was measured by a 25-question questionnaire (Cronbach’s alpha = .98) and patient satisfaction by 20-question questionnaire. (Cronbach’s alpha = .75) Data were analyzed using Chi-Square to test the level of significance at α = .05. The result of the statistical analysis showed that 64.1% of the subjects indicated that the manner of the implementation of the discharge planning is categorized as good enough and 55.1 % of the subjects expressed not good satisfaction with the result of the program. The correlation between these two variables is 0.541 It is concluded that there is a significant correlation between the implementation of discharge planning to inpatient satisfaction.
Development of Power Vegan Cupcake
Authors: Llagas Johnson , Datoy John Jayson , Cerna Patricia Dela , Laborde Gladys Mae , Estrada Miriam , Balagtas Maribel , Oasan Ruchel 
Published: June 2022

The objective of this study was to develop a healthy eating on the go for busy people. The Power Vegan Cupcake is a plant-based, nutrient-dense product, and is made from local plant-based ingredients. Saluyot and soymilk were used as replacements for egg and milk. Brown rice flour, muscuvado, banana, raisins, and peanuts made the cupcake a complete food. The dry ingredients were sifted and mixed. Saluyot and pandan leaves were boiled for 15 minutes and then cooled, blended, and strained. The saluyot puree and pandan juice were then mixed with the dry ingredients, soy milk, and vanilla. The batter was mixed, and raisins and banana were added. The batter was baked in an oven for 25 minutes at 200°C. Each Power Vegan Cupcake (70g) contained 41.7g of carbohydrates, 4.7g of protein, and 3.12g of fat for a total calorie content of 198.4kcal. It also contained 28.75ug of Vitamin A, 2.4mg of Vitamin C, 50.6mg of calcium, 1.5mg of iron, 0.17mg of thiamin, 0.19mg of riboflavin, 2.93mg of niacin, and 98.7mg of phosphorus. The product was found to contain a higher amount of carbohydrates, protein, and micronutrients compared to regular cupcakes on the market. Thirty respondents, ages 18-29, evaluated the product. The results showed a rating of like very much from 63%, 53%, and 50% of the evaluators in terms of appearance, texture, and taste, respectively. Advance development of saluyot as egg substitute for strict vegetarian foods is recommended.
Social and Spiritual Determinants of Mental Health among Persons Deprived of Liberty: A Basis for Program Development
Authors: Ilagan Gia Zonuel G. , Quidilla Karen Ann D. , Elkanah Diana A. , Saban Rona Beth S. 
Published: June 2022

Issues on mental health among Persons Deprived of Liberty [PDL] are seen but mostly are not recognized in the Philippines. This study aimed to determine the social and spiritual determinants of mental health among PDLs. Self-esteem, aggressiveness, and outlook are considered the dimensions of mental health in this study. This research was also conducted to establish the predictors of mental health among the respondents. A descriptive correlational research design was utilized. Through convenience sampling, 143 PDLs from a jail institution in Region IV-A were selected. A self-constructed questionnaire which had undergone validation and reliability testing was used. Data gathered were analyzed using descriptive statistics, Pearson’s correlation, Analysis of Variance (ANOVA), and linear regression. The study revealed that the respondents have high levels of social and spiritual determinants, high levels of self-esteem, positive outlook, and low levels of aggression. Aggressiveness and outlook are significantly related to social and spiritual determinants, while self-esteem is not significantly related to both determinants. Furthermore, gender is significantly related to self-esteem and the outlook of the respondents; age has a significant relationship with aggressiveness; and the length of imprisonment has no significant relationship with all dimensions of mental health. Predictors for each mental health dimension were also determined. The gender of the respondents was the only predictor for self-esteem; social determinant and the age of the respondents were the predictors for aggressiveness. Also, the spirituality of the respondents was the only predictor for their outlook. A proposed program was made based on the results of the study. This program, if implemented, aims to enhance the promotion of mental health among Persons Deprived of Liberty.