bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thoracic endovascular aortic repair for retrograde type a intramural hematoma or aortic dissection with intimal disruption in the descending aorta: Systematic review and meta-analysis
Authors: Naito Noritsugu , Takagi Hisato 
Published: February 2025

Background While thoracic endovascular aortic repair (TEVAR) for type B aortic dissection is widely used, its use in cases of type A acute aortic syndrome remains limited. This meta-analysis was conducted to determine the outcomes of TEVAR for retrograde type A intramural hematoma (IMH) and aortic dissection with intimal disruption located in the descending aorta. Methods Systematic searches were conducted up to April 2024. Pooled proportions of perioperative and late outcomes were computed. Additionally, standard mean differences (SMD) with 95% confidence intervals (CI) in aortic dimensions following TEVAR were calculated. Kaplan-Meier curves, derived from individual patient data extracted from the studies, were utilized to elucidate long-term all-cause mortality. Results A systematic review identified 13 non-randomized studies encompassing 288 patients. Pooled proportions revealed short-term mortality at 1%, with incidences of spinal cord injury, stroke, new intimal tear/dissection in the ascending aorta, aortic rupture, necessity for aortic re-intervention, and late mortality each recorded at 1%, 1%, 3%, 1%, 6%, and 7%, respectively. Substantial reductions in the diameters of the ascending aorta, descending aorta, IMH/false lumen of the ascending aorta, and IMH/false lumen of the descending aorta were observed post-TEVAR (SMD [95% CI] = 1.11 [0.82–1.39], 1.02 [0.58–1.47], 3.06 [2.39–3.74], and 2.77 [2.28–3.26], respectively). The anticipated 5-year survival rate stood at 91.1%. Conclusion This meta-analysis suggests TEVAR may offer a viable and safe therapeutic option for retrograde type A acute aortic syndrome. Nevertheless, definitive conclusions are hindered by the scarcity of available data.
Long Term Improvement of Episodic Memory in Stroke Patients Following a Short Treatment with Prism Adaptation and Serious Games
Authors: Oliveri Massimiliano , Stanzione Agostino , Caruso Giulia , Di Garbo Agnese , Turriziani Patrizia , Carlesimo Giovanni Augusto 
Published: February 2025

Episodic memory deficits are frequently encountered following stroke. Rehabilitation of these deficits is often associated with short term effects that do not persist at follow up times. Neuromodulation tools acting on alterations of excitation/inhibition dynamics could be useful for rehabilitation of episodic memory. Prism adaptation with visual field deviation ipsilateral to the affected hemisphere can specifically modulate brain excitability and lead to improvement of cognitive deficits in post-stroke patients. Here we investigated whether prism adaptation followed by digital cognitive training could induce long term improvement of episodic memory deficits in stroke patients as compared with traditional rehabilitation. Sixty stroke patients were recruited for the study. Thirty patients were treated with prism adaptation combined with serious games targeting executive processes, with a ten days protocol (experimental group); thirty patients were treated with conventional rehabilitation (control group). Patients were tested with a battery of neuropsychological tests, including verbal and visual episodic memory tasks at four times: at baseline (T0); immediately after the end of the rehab protocol (T1); after 3 months (T2); after six months (T3). The main results showed a significant long term effect of the experimental treatment on both immediate and delayed recall phases of the visual episodic memory task. The effects were not linked to the affected hemisphere (right vs. left), nor to the hemorrhagic or ischemic type of stroke nor to the cortical or subcortical site of lesion. These findings show for the first time an improvement of long term memory in stroke patients following the use of a medical device combining prism adaptation and digital cognitive training, paving the way to novel rehabilitation techniques for cognitive deficits in stroke.
Acute stress exposure in healthy oil and gas field workers and early post-traumatic stress disorder symptoms: A lesson from the COVID-19 crisis
Authors: Fitriani Dewi Y , Mansyur Muchtaruddin , Raharjanti Natalia W , Adi Nuri P , Isbayuputra Marsen , Ramadianto Adhitya S , Nugrahadi Nadia R , Yo Edward C , Pujo Jean M , Kallel Hatem 
Published: February 2025

Introduction During the COVID-19 pandemic, the oil and gas industry had to adopt coping strategies. These changes might contribute to early increased mental health issues among workers. This study aimed to assess the prevalence and associated factors to early post-traumatic stress disorder (PTSD) symptoms among healthy Indonesian oil and gas field workers during the COVID-19 pandemic. Method A cross-sectional study was conducted from November 2020 to January 2021. We investigated healthy field employees working during the pandemic. Data on the subjects’ PTSD symptoms were collected using the PTSD Checklist–Civilian (PCL-C) Version. Results A total of 1542 completed forms were analyzed. The prevalence of PTSD symptoms was 44.8%, with 9.1% of very severe forms. Independent factors associated with PTSD symptoms were female gender ( p = .013, OR 1.72 [95% CI 1.12–2.63]), change in work system ( p = .006, OR 1.37 [95% CI 1.09–1.71]), increased workload ( p < .001, OR 2.10 [95% CI 1.63–2.71]), and decreased income ( p = .041, OR 1.44 [95% CI 1.02–2.05]). Conclusion The COVID-19 crisis and its impact on working conditions were significant stressors that contributed to a high prevalence of PTSD symptoms among oil and gas company workers. Therefore, implementing well-being programs is essential during acute challenges that lead to changes in work systems.
Does mild COVID-19 in healthcare workers affect functional capacity and work performance in short term?
Authors: Oke Deniz , Gulec Meryem Guneser , Yalcinkaya Ebru Yilmaz , Taskiran Ozden Ozyemisci 
Published: February 2025

Background Disproportionately increased workload is one of the main reasons affecting work performance. Healthcare workers who got infected by COVID-19 were further affected mentally and physically which had an impact on their work performance. Objective In this study, we aimed to show whether work performance is affected even in people with mild Covid 19 disease or whether it is a part of Post-Acute COVID-19 Syndrome (PACS). Methods Thirty healthcare workers in a tertiary hospital had COVID-19 one month ago and gender and age matched 30 healthy workers without a history of COVID-19 (control group) was enrolled between January 2021 and March 2021. Work performance was assessed on a 7-point Likert scale. Participants performed 1-min sit-to-stand test (1MSTS), 5 times sit-to-stand test (5TSTS), and 6-min walk test (6MWT). Results All participants in the COVID-19 group had a mild (non-hospitalized) form of the disease. 23 patients had ongoing symptoms 4–7 weeks after the initial symptoms of COVID-19 (fatigue/malaise (n = 9), myalgia/arthralgia (n = 7), cough (n = 7), loss of smell/taste (n = 5), headache (n = 5), dyspnea (n = 4), and diarrhea (n = 1). The increase in systolic blood pressure after 6MWT was higher in the COVID group (p = 0.018). Conclusion The functional status and work performance in healthcare workers with COVID-19 infection were negatively affected in the first month even if the disease severity was mild. It is important to prevent both acute and long-term physical and mental complications of the disease and to ensure that these strategies improve the functional status and work performance of healthcare professionals.
Effectiveness of Aerobic Treadmill Training on Walking Distance in Patients with Multiple Sclerosis with Moderate Disability: A Randomised Controlled Multicentre Trial
Authors: Massot C , Guyot MA , Blanchard A , Norberciak L , Donze C 
Published: February 2025

Background Patients with Multiple Sclerosis (PwMS) have gait disorders. The efficiency of treadmill training on walking distance is debatable. Objective This study evaluated the efficacy of a 6-week treadmill training program at heart rate at the first ventilatory threshold (HRVT1) on walking distance compared with a control group in PwMS. Methods This prospective, multicenter study included 46 PwMS with moderate disability which randomized into training group (TG) and control group (CG). Patients performed cardiopulmonary exercise test to determine HRVT1. TG realized walking treadmill training program at HRVT1: 18 sessions (3 sessions/week) over 6 weeks. The distance on the six-minute walk test (6MWT), Timed 25 foot walk, patient-reported walking ability, berg balance scale, fatigue scale, the HR at the end of the 6MWT (HR6MWT) were collected at baseline, 6 weeks and 12 weeks. Results The 6MWT distance showed a significant overall group effect (30.6 m; 95%CI = (6.6; 54.6); p = 0.017). The perceived impact of walking was significantly decreased in the TG (−6.1; 95% CI = (−9.2; −2.9); p = 0.0006). No correlation was found between HRVT1 and HR6MWT. Conclusion Aerobic treadmill training significantly enhanced walking distance and reduced perceived walking difficulties in PwMS.
Innovation of dynamic management model for teaching resources of business administration in cloud computing environment
Authors: Li Wenle , Li Wenjun 
Published: February 2025

This article analyzes the characteristics of security redundancy structure and cloud computing in the dynamic management system of business management teaching resources. Taking the ZC system as an example, based on the integration of blockchain decentralization technology, the overall scheme of a cluster-based ZC service system based on cloud computing is proposed. Develop and design custom consensus algorithms and smart contracts that align with the foundational principles of decentralized blockchain technology. By implementing a reputation-based evaluation system for nodes within the network, the influence of malicious nodes on the consensus procedure can be effectively mitigated. This paper investigates the potential risk of single-point failures in the security redundancy architecture of the dynamic management system for business administration teaching resources, particularly within the ZC subsystem, which is critical to ensuring system integrity. Create a blockchain-based program and propose a deployment method for a minimal system using containerization, while also introducing an attack tree analysis consensus algorithm to address potential information security risks. Assess the impact of factors such as block size and the number of nodes in the cluster on the throughput, consensus latency, and cycle stability of the consensus algorithm, providing a comprehensive evaluation of system performance. The proposed ZC cluster in this study complies with the SIL4 security standard, offering superior reliability compared to traditional ZC systems in terms of security and fault tolerance. Regarding system availability, the PoTH consensus algorithm, as proposed, exhibits an average delay of 4.33 ms with a standard deviation of 0.173 ms across multiple trials. The algorithm’s cycle stability ensures smooth operation of up to 40 trains while remaining within the maximum delay threshold of 100 ms.
Postoperative Outcomes Following Metacarpal Neck Fractures Treated With Intramedullary Screws Versus Closed Reduction Percutaneous Pinning
Authors: Bridges Tiffany N. , Lazaro Johnlevi S. , Kwan Stephanie A. , Jones Christopher M. , Matzon Jonas L. , Rivlin Michael 
Published: February 2025

Background: Metacarpal neck fractures are frequently encountered by hand surgeons. Certain operative metacarpal neck fractures are amenable to both retrograde intramedullary screw (IMS) fixation and closed reduction percutaneous pinning (CRPP). The purpose of this study was to compare functional outcomes and complications following these two techniques. Methods: All patients with metacarpal neck fractures treated with either IMS or CRPP from 2015 to 2021 at a large private academic institution were retrospectively identified. Electronic medical records were reviewed for demographics, Quick Disabilities of Arm, Shoulder, and Hand (qDASH) scores, metacarpophalangeal joint range of motion (ROM), and complications. Results: A total of 113 patients, consisting of 57 in the IMS cohort and 56 in the CRPP cohort, were included. The CRPP cohort was significantly younger, otherwise demographics were similar between both groups. Both cohorts had similar preoperative (47.5 IMS vs 43.9 CRPP), postoperative (17.6 IMS vs 9.9 CRPP), and delta (35.5 IMS vs 34.0 CRPP) qDASH scores. Retrograde IMS allowed for greater flexion at 4 to 6 weeks (81° vs 65°) postoperatively. The overall incidence of complications was similar among IMS and CRPP (21.1% vs 17.9%), although IMS had significantly more major complications (8.8% vs 0%). Conclusions: Despite earlier return to ROM, operative fixation of unstable metacarpal neck fractures with retrograde IMS may be at higher risk of major hardware complications and extensor lag.
Antiplatelet and Anticoagulation Usage During Ultrasound-Guided Incisionless Thread Carpal Tunnel Release
Authors: Dean Kaylie P. , Smith Brandon J. , Shin Alexander Y. , Brault Jeffrey S. 
Published: February 2025

Background: Carpal tunnel syndrome (CTS) is the most common peripheral nerve entrapment syndrome. The thread carpal tunnel release (TCTR) is an incision-less ultrasound-guided approach to divide the transverse carpal ligament. This retrospective case series aims to identify and assess the bleeding risks associated with continuing anticoagulation or antiplatelet therapy during TCTR. Methods: Retrospective chart review with follow-up questionnaires/surveys. One hundred and fourteen adult patients who were using antiplatelet or anticoagulation medication underwent 164 TCTR procedures during 2018 to 2023 at a single institution (tertiary care hospital) from June 29, 2018, and August 11, 2023. A chart review was performed to identify patients on antiplatelets or anticoagulants at the time of the procedure and to determine if there were any adverse events associated with continuing or holding their antiplatelet or anticoagulant therapy. Results: There were no significant complications associated with continuing or holding anticoagulation or antiplatelet therapy during TCTR. Conclusions: Continuing antiplatelet therapy during TCTR appears safe. The decision to continue antiplatelet or anticoagulation therapy should be made on a case-by-case basis.
Satisfaction With Teleneurology in Low Resource Setting: A Cross-Sectional Study Among Patients and Healthcare Providers
Authors: Ansari Mohammed Farhan , Menon Deepak , Ittycheria Milu Anna , Govindaraj Sarath , Shahed Rehan , Boopalan Deenadayalan , Parthasarathy Rajani , Rao Girish N , Arshad Faheem , Alladi Suvarna ,   on behalf of the Karnataka Brain Health Initiative (KaBHI) Consortium
Published: February 2025

Background and Objectives Teleneurology has become instrumental in extending neurologic care in remote and underserved areas, enhancing access, and potentially improving patient outcomes while reducing costs. This study evaluates the satisfaction of both patients and healthcare providers with teleneurology services for common neurological disorders. Methods In this single-center, prospective observational study, 58 patients suffering from headache, epilepsy, stroke, or dementia were recruited through the “Karnataka Brain Health Initiative.” Teleconsultations were facilitated via Zoom, incorporating brief neurological examinations. Satisfaction levels were gauged using the Telemedicine Satisfaction Questionnaire (TSQ) for patients and the Patient and Physician Satisfaction with Monitoring Questionnaire (PPSM) for healthcare providers. Results Of the 58 patients enrolled, 18 had headache, 12 epilepsy, 13 stroke, and 15 dementia, with a mean age of 43.7 years. All completed the TSQ, yielding a mean score of 4.47 ± 0.41. The average teleconsultation lasted 21.21 minutes. The PPSM questionnaire, completed by neurologists for all patients, resulted in a mean score of 4.33 ± 0.44. Of these, 36 consultations initiated by primary care physicians had a PPSM mean score of 4.47 ± 0.51. Agreement on quality of care was 60%, time-saving benefit 98%, and willingness for future use 95%. Discussion The findings indicate high satisfaction among both patients and providers, underscoring the effectiveness of teleneurology in delivering quality care comparable to in-person consultations. The positive feedback from primary care physicians highlights teleneurology’s potential as an integral component of healthcare delivery in low-resource settings.
A Study of Cesarean Deliveries From a Single Midwestern Residency Program: Total Surgical Time, Incision-to-Delivery Time, and Neonatal Apgar Scores
Authors: King Jeremy , Geske Jenenne , Sricharoen Chanont , Khandalavala Birgit 
Published: February 2025

Background: Cesarean delivery surgical quality indicators and outcomes support the surgical skills of family medicine physicians. These data have educational and clinical implications yet are largely unexplored. Our study updated cesarean surgical times, incision-to-delivery time, and neonatal Apgar scores from a midwestern family medicine residency program. Methods: All cesarean deliveries performed by family medicine faculty from January 2012 to March 2021 were reviewed. Total surgical time, incision-to-delivery time, Apgar scores at 1 and 5 min, and maternal demographic information were recorded. Results: 320 cesarean deliveries were reviewed. The average total surgical procedure time was 64.3 min (SD = 17.9) and incision-to-delivery time was 9.5 min (SD = 4.9). The average 1-min Apgar score was 7.5 (SD = 1.8) and the average 5-min Apgar score was 8.7 (SD = 1.0). There were no significant correlations between 1- and 5-min Apgar scores and procedure times. Conclusion: Cesarean delivery quality indicators from family medicine faculty are updated and appear similar to those reported previously in studies that did not include the presence of learners. This EMR-based study provides baseline information for future surgical cesarean delivery quality improvement and outcomes research.
Prevalence of Spin in Reviews on Intrawound Application of Vancomycin for Surgical Site Prophylaxis in Spine Surgery
Authors: Telang Sahil S. , Podosin Mallory A. , Fathi Amir , Kotlier Jacob L. , Feingold Cailan L. , Alluri Ram K. , Liu Joseph N. 
Published: February 2025

Study Design Systematic Review. Objectives Systematic reviews and meta-analyses that aggregate data on the intrawound application of vancomycin for surgical site infection (SSI) prophylaxis in spine surgeries are at an increased risk of spin, the overstating of beneficial effects of an intervention. The purpose of this study was to identify studies that coalesce outcomes of intrawound vancomycin SSI prophylaxis in spine surgeries and define the prevalence and types of spin in the identified literature. Secondarily, this study aimed to identify patterns within study characteristics that were associated with certain spin types. Methods This study was conducted using the Preferred Reporting Items for Systemic Reviews and Meta-Analyses guidelines. A search was performed in 4 databases (PubMed, SCOPUS, Medline and Cochrane) for systematic reviews and meta-analyses on intrawound vancomycin use for SSI prophylaxis in spine surgeries. Two authors independently assessed studies for inclusion criteria and then aggregated study characteristics: titles, publication journal and year, authors, level of evidence, etc. Each study was subsequently evaluated for the presence of 15 different spin types. Statistical analysis was performed for patterns between spin prevalence and study characteristics. Results From the database search, 18 studies met the inclusion criteria. In total, 13 studies (72%) were found to have spin. The most common types of spin identified were spin type 9 (“Conclusion claims the beneficial effect of the experimental treatment despite reporting bias”), found in 9 (50.00%) studies and type 3 (“Selective reporting of or overemphasis on efficacy outcomes or analysis favoring the beneficial effect of the experimental intervention”), found in 7 (38.89%) studies. Conclusions There is a high prevalence of spin in systematic reviews and meta-analyses on the intrawound application of vancomycin for SSI prophylaxis in spine surgery. Our analysis demonstrated that studies tended to selectively report positive findings while minimizing negative outcomes within abstracts.
The Association Between Clival Axial Angle and Distal Junctional Failure After Craniocervical Fusion
Authors: Schneider Daniel , Gandhi Shashank V. , Ward Max , White Timothy G. , Brown Ethan D. L. , Pennington Zach , Zimering Jeffrey , Latefi Ahmad , Rekate Harold , Sciubba Daniel M. , Lo Sheng-fu Larry 
Published: February 2025

Study Design Retrospective Cohort. Objectives Craniovertebral instability can arise from various congenital or acquired conditions, but definitive management often requires craniocervical fusion. This study evaluates whether postoperative clivo-axial angle (CXA) can predict distal junctional failure in patients undergoing craniocervical fusion. While postoperative alignment of the head and cervical spine can be quantified via the CXA, it is unclear whether the CXA can predict distal junctional failure. Methods All patients undergoing craniocervical decompression and fusion (CCF) for craniovertebral instability between 2012 and 2023 at a single institution were identified. Patients experiencing adjacent segment disease (ASD) were identified and compared to those without said pathology based on CXA, Grabb-Oakes line (pBC2), and the presence of cervical kyphosis, cervical disc degeneration, or subluxation on pre- and postoperative imaging. Statistical analysis included Shapiro-Wilk tests for normality, followed by independent t-tests or Mann-Whitney U tests with FDR adjusted P values as appropriate, and univariable logistic regression. Results 71 patients were included, of whom ten (14.3%) developed distal junctional kyphosis and 3 (4.3%) developed cervical spondylolisthesis. The median postoperative CXA was significantly lower in non-ASD patients (144° [IQR: 140-148°] vs 158° [IQR: 153-162°]; P < .001) and logistic regression showed that each 10° degree increase in CXA was associated with a 6.7-fold higher odds of ASD. Conclusions We found craniocervical alignment, as assessed by CXA, independently predicted distal junctional disease in patients undergoing craniocervical fusion, possibly due to low preoperative CXA in these patients. Large increases in CXA may contribute to postoperative instrumentation failure.