bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cost-effectiveness of a collaborative care model among patients with type 2 diabetes and depression in India
Authors: Emmert-Fees Karl M. F. , Laxy Michael , Patel Shivani A. , Singh Kavita , Poongothai Subramani , Mohan Viswanathan , Chwastiak Lydia , Narayan K M  Venkat , SAGAR RAJESH , Sosale Aravind , Anjana Ranjit Mohan , Sridhar Gumpeny R. , Tandon Nikhil , Ali Mohammed K 
Published: November 2022

<p> </p>
<p><strong>Objective</strong></p>
<p>To assess the cost-effectiveness of collaborative versus usual care in adults with poorly-controlled type 2 diabetes and depression in India.</p>
<p><strong>Research Design and Methods</strong></p>
<p>We performed a within-trial cost-effectiveness analysis of a 24-month parallel, open-label, pragmatic randomized clinical trial at four urban clinics in India from multipayer and societal perspectives. The trial randomized 404 patients with poorly-controlled type 2 diabetes (HbA1c≥8.0% or systolic BP≥140mmHg or LDL-c≥130mg/dl) and depressive symptoms (PHQ-9≥10) to collaborative care (support from non-physician care coordinators, electronic registers, and specialist-supported case review) for 12 months, followed by 12 months usual care or 24 months usual care. We calculated incremental cost-effectiveness ratios (ICER) in Indian rupees (INR) and international dollars (Int’l) and the probability of cost-effectiveness using quality-adjusted life years (QALYs) and depression-free days (DFDs).</p>
<p><strong>Results</strong></p>
<p>From a multipayer perspective, collaborative care costed additional INR309,558 (Int’l-$15,344) per QALY and additional INR290.2 (Int’l-$14.4) per DFD gained compared to usual care. The probability of cost-effectiveness was 56.4% using a willingness-to-pay of INR336,000 (Int’l-$16,654) per QALY (~3-times per-capita GDP). The willingness-to-pay per DFD to achieve a probability of cost-effectiveness >95% was INR401.6 (Int’l-$ 19.9). From a societal perspective, cost-effectiveness was marginally lower. In sensitivity analyses, integrating collaborative care in clinical workflows reduced incremental costs by ~47% (ICER: 162,689/QALY; cost-effectiveness probability: 89.4%) but cost-effectiveness decreased when adjusting for baseline values.</p>
<p><strong>Conclusions</strong></p>
<p>Collaborative care for patients with type 2 diabetes and depression in urban India can be cost-effective, especially when integrated in clinical workflows. Long-term cost-effectiveness might be more favorable. Scalability across lower- and middle-income country settings depends on heterogeneous contextual factors. </p>
Deficits and Disparities in Early Uptake of GLP-1 Receptor Agonists and SGLT2 Inhibitors among Medicare-insured Adults Following a New Diagnosis of Cardiovascular Disease or Heart Failure
Authors: Cromer Sara J. , Lauffenburger Julie C. , Levin Raisa , Patorno Elisabetta 
Published: November 2022

<p> </p>
<p>Objective: To examine the association of race/ethnicity and socioeconomic deprivation with initiation of guideline-recommended diabetes medications with cardiovascular benefit (glucagon-like peptide-1 receptor agonists (GLP1-RA) and sodium-glucose co-transporter-2 inhibitors (SGLT2i)) among older adults with type 2 diabetes (T2D) and either incident atherosclerotic cardiovascular disease (ASCVD) or congestive heart failure (CHF).</p>
<p>Research Design and Methods: Using Medicare data (2016-2019), we identified 4,057,725 individuals over age 65 with T2D and either incident ASCVD or CHF. We estimated incidence rates (IR) and hazard ratios (HR) of GLP1-RA or SGLT2i initiation within 180 days by race/ethnicity and zip code-level Social Deprivation Index (SDI) using adjusted Cox proportional hazards models. </p>
<p>Results: IRs of GLP1-RA or SGLT2i initiation increased over time but remained low (<0.6 initiations per 100 person-months) in all years studied. Medication initiation was less common among those of Black or Other race/ethnicity (HR 0.81 [95% confidence interval (CI) 0.79-0.84] and HR 0.84 [95%CI 0.75-0.95], respectively) and decreased with increasing SDI (HR 0.96 [95%CI 0.96-0.97]). Initiation was higher in ASCVD than CHF (0.35 vs. 0.135 initiations per 100 person-months). Moderate (e.g., nephropathy, non-alcoholic fatty liver disease) but not severe (e.g., advanced chronic kidney disease, cirrhosis) comorbidities were associated with higher probability of medication initiation.</p>
<p>Conclusions: Among older adults with T2D and either ASCVD or CHF, initiation of GLP1-RA or SGLT2i was low, suggesting a substantial deficit in delivery of guideline-recommended care or treatment barriers. Individuals of Black and Other race/ethnicity and those with higher area-level socioeconomic deprivation were less likely to initiate these medications.</p>
REVITALISASI KEBIJAKAN PEMBELAJARAN AL ISLAM DAN MUHAMMADIYAHAN DI UNIVERSITAS MUHAMMADIYAH METRO
Authors: Sujino Sujino , Marlisa Lusi 
Published: November 2022

Pendidikan Al-Islam dan Kemuhammadiyahan di Perguruan Tinggi Muhammadiyah dapat berfungsi sebagai kekuatan gerakan bagi Muhammadiyah (Quwwatul Harokah al-Muhammadiuah) karena dapat menjadi basis kekuatan spiritual, moral, dan intelektual. Pendidikan Al-Islam dan Kemuhammadiyahan (AIK) juga sebagai identitas karakter warga kampus. Perkembangan peradaban yang cepat dan pesat dengan teknologi informasi di era digitalisasi serta inovasi teknologi (gawai, internet, media sosial) yang semakin berkembang, sangat mempengaruhi daya serap informasi, pemahaman dan praktik keislaman mahasiswa. Kesenjangan dalam ilmu pembelajaran AIK masih mnyisakan masalah, antara lain: kurikulum masih belum menggambarkan standar lulusan dan masih menitik beratkan pengetahuan. Dosen pengampu belum disiapkan secara profesional, dosen pengampu belum memilki komitment tinggi pada Muhammadiyah dan dosen AIK belum dimiliki semua jurusan, termasuk Kebijakan Universitas Muhammadiyah Metro belum menempatkan prioritas penting bagi pendidikan AIK. Tujuan dari penelitian ini untuk mengatahui Gambaran dan standar Pembelajaran AIK di Universitas Muhammadiyah Metro, serta untuk Mengetahui Revitaliasi Kebijakan LPM dan Wakil Rektor 4 terhadap Pembelajaran AIK di Univeritas Muhammadiyah Metro. Metode yang digunakan dalam penelitian ini menggunakan jenis penelitian kualitatif deskriptif, dengan menggunakan pendekatan studi kasus (case study). Penelitian ini memusatkan diri secara intensif pada satu obyek tertentu yang mempelajarinya sebagai suatu kasus.Revitalisasi kebijakan pembelajaran AIK didasari oleh realitas di Universitas Muhammadiyah Metro adalah keniscayaan. Reliata yang kian melemah itu perlu segera di respon positif. Revitalissi berarti menggaerahkan AIK dalam dimensi transfer knowlagde dan transfer value, memvitalkan kembali fungsi AIK yang sudah berjalan. Dengan mempertimbangkan beberapa aspek. Tujuan pendidikan Muhammadiyah yang dalam grand Desain rencana yang akan mendorong terwujudnya Indonesia yang berkemajuan yang dimulai dengan revitalisasi AIK di perguraun Muhammadiyah khususnya Universitas Muhammadiyah Metro.
Reseña de Rodolfo Rozengardt y Fabio Krivzov (compiladores) - La Pampa en Movimiento. 30 años. 1ª edición – Buenos Aires: Editores asociados, 2021. 422 páginas. ISBN 978-987-4150-52-3
Authors: Rodríguez Piñero Cristian David 
Published: November 2022

Reseña de La Pampa en Movimiento. 30 años de R. Rozengardt y F. Krivzov (comp.) por Cristian David Rodríguez Piñero.
Open data application to evaluate exposure of wildfire to water resources: A case study in Johor, Malaysia
Authors: Sanin Fara Aiza Md , Alias Nor Eliza , Kanniah Kasturi Devi , Kadir Mariyana Aida Ab. , Mohamad Izni Izzati , Paramasivam Rasnavi 
Published: November 2022

Abstract
Climate change impacts wildfire events as well as water availability. Exposure of water resources to wildfire can reduce water quality supplied to humans and resulting health problems. On the other hand, water resources such as rivers and ponds are essential in wildfire firefighting. This paper intended to assess spatially the exposure of water resources to wildfire. A case study in Johor, Malaysia is utilised to asses and determine locations of water bodies in an area which are vulnerable to wildfire. Post wildfire runoff water can contaminate water resources. Fire data collected by MODIS from 2000–2020 are used to create a hotspot map. Water resources and waterbody data originated from Department of Surveying and Mapping Malaysia used to identify the stream and dams that are exposed to wildfire. 5 class exposure level has been set to show the degree of closeness of water resources to wildfire hotspot area. Using the spatial analysis method, low to high level of potential wildfire-water exposures were able to be locate. Analysis shows, 7% of Johor’s water sources is exposed to medium levels of wildfire, while just 1% is exposed to the highest levels. The majority of the streams have very low levels of exposure. In addition, the wildfire-water exposure map aids in first respondent preparedness and planning.
Topical Diagnosis and Determination of the Primary Hyperaldosteronism Variant
Authors: Shidlovskyi Viktor O. ,   Surgery Department, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine, Shidlovskyi Olexandr V. ,   Surgery Department, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine, Tovkai Oleksandr A. ,   Ukrainian Scientific and Practical Center of Endocrine Surgery, Endocrine and Tissue Transplantation of the Ministry of Health of Ukraine, Kyiv, Ukraine, Sheremet Michael I. ,   First Surgery Department, Bukovinian State Medical University, Chernivtsi, Ukraine,   Michael I. Sheremet, First Surgery Department of Bukovinian State Medical University, Holovna str., 191, 58018, Chernovtsy, Ukraine, E-mail: mihayl71@gmail.com; Phone: +380956064607, Maksymyuk Vitaliy V. ,   First Surgery Department, Bukovinian State Medical University, Chernivtsi, Ukraine, Tarabanchuk Volodimir V. ,   First Surgery Department, Bukovinian State Medical University, Chernivtsi, Ukraine, Ivanovych Shved M. ,   Department of First Emergency Medical Aid and Emergency Medical Treatment, Ternopil, Ukraine, Heryak Mykolaivna S. ,   Second Department of Obstetrics and Gynecology, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine, Andreychyn Mykhailovych S. ,   Department of Propaedeutic of Internal Medicine and Phthisiology, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine, Hanberher Igorivna I. ,   Department of Propaedeutic of Internal Medicine and Phthisiology, I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine, Piddubna Antonina A. ,   Department of Clinical Immunology, Allergology and Endocrinology, Bukovinian State Medical University, Chernivtsi, Ukraine
Published: November 2022

Laboratory diagnosis of primary hyperaldosteronism is based on determining blood levels of aldosterone, renin on request, potassium, and sodium. The results of these studies are significantly influenced by drugs, preparation for the study and blood collection methods, age, gender, and concomitant diseases. The work analyzes the factors influencing the results of the study of aldosterone and identifies the main ways of their exclusion at each stage of the diagnosis. Their neglecting is the determining factor in obtaining false results, diagnostic errors, the selection of ill-treatment tactics, and inadequate treatment. All these diagnostic problems are covered in a variety of ways in the review, which is based on the analysis of results of individual authors’ research and practical and clinical recommendations from leading world endocrinological associations.
Results of laboratory diagnostics of PHA depend on the influence of many factors. Among them, it is essential to use different medication drugs, the rules for preparing for the study, and the method of conducting it. In assessing the results of research, it is necessary to take into account not only the indicators of the level of aldosterone in the blood but also the features of the clinical course of the disease, its compliance to the drug therapy, age, and gender of the patients.
ANALISIS KINERJA ALGORITMA PEMILIHAN PENGGUNA DENGAN KOMPLEKSITAS RENDAH BERBASIS KOMBINASI ROUND-ROBIN PADA SISTEM MASSIVE MIMO
Authors: Nauvaldi Rayhan , Adriansyah Nachwan Mufti , Setiawan Dhoni Putra , Astuti Rina Pudji 
Published: November 2022

Sistem komunikasi generasi kelima (5G) menuntut kinerja yang lebih tinggi dari generasi sebelumnya. Sistem Massive Multiple Input Multiple Output (MIMO) muncul sebagai solusi untuk mengatasi generasi sebelumnya yang tidak dapat memenuhi permintaan data dalam jumlah besar. Penggunaan Massive MIMO ini memungkinkan diciptakannya multiple beam sehingga throughput dapat meningkat lebih besar daripada generasi sebelumnya. Sistem Base Station (BS) dengan banyak antena tidak dapat melayani pengguna dalam jumlah besar secara bersamaan. Maka dari itu sangat penting untuk memilih layanan pengguna yang akan dilayani secara bersamaan dan menentukan jumlah optimal pengguna yang akan dilayani. Penelitian ni mengusulkan algoritma pemilihan layanan pengguna untuk mencapai spektral efisiensi tinggi dan interferensi kecil. Algoritma yang diusulkan adalah Capacity-Based User Selection, Frobenius Norm-Based User Selection, dan Chordal Distance User Selection (CDUS) yang dikombinasikan dengan algoritma Round-Robin (RR). Berdasarkan simulasi yang telah dilakukan, algoritma pemilihan layanan pengguna yang dikombinasikan dengan algoritma RR memberikan kinerja yang baik dalam hal sumrate menggunakan algoritma Capacity-RR dengan nilai 673 bps/Hz, tingkat fairness pada algoritma CDUS-RR memiliki indeks fairness dengan nilai rata-rata 3,29, dan kompleksitas pada algoritma CDUS-RR memiliki rata-rata runtime sebesar 0,62 detik. Hasil penelitian ini diharapkan dapat berkontribusi dalam pengembangan penjadwalan pengguna pada Massive MIMO.
Kata Kunci: : Massive MIMO, capacity-based user selection, frobenius norm-based user selection, chordal distance user selection, round-robin.
PENERAPAN METODE KENDALI CONTROL LYAPUNOV-BARRIER FUNCTION (CLBF) PADA MODEL QUADCOPTER
Authors: Cahyo Farhan Dwi , Romdlony Muhammad Zakiyullah , Rosa Muhammad Ridho 
Published: November 2022

Penelitian ini melakukan penerapan metode kendali Control Lyapunov-Barrier Function (CLBF) pada model quadcopter menggunakan perangkat lunak Simulink. Kendali CLBF digunakan untuk menggerakkan model quadcopter dari posisi awal model ke posisi tujuan. Kendali CLBF juga berfungsi untuk menghindari unsafe states atau penghalang yang dimiliki oleh model quadcopter. Hasil penelitian ini menunjukkan bahwa penerapan kendali CLBF pada model quadcopter telah berhasil dilakukan. Percobaan model quadcopter menghasilkan nilai rata-rata galat sebesar 0,926% dan berhasil menghindari penghalang dengan rata-rata nilai terdekat terhadap penghalang sebesar 0,079 m.
Kata Kunci: control Lyapunov-barrier function, model quadcopter, simulasi
Identifying Inflammatory Gene Expression Signatures for Skin and Soft Tissue Infections
Authors: Yeh Jennifer , Pereira da Silva Marcelo , Raff Adam , Foreman Ruth 
Published: November 2022

Background: Misdiagnosis of skin and soft tissue infections (SSTIs) due to clinical mimics can result in delay of care, unnecessary antibiotic exposure, and inappropriate hospitalization. Comprehensive screening of inflammatory genes in SSTIs could identify biomarkers to distinguish SSTIs from mimics.
Methods: We performed a search of the MGH James Homer Wright Pathology Laboratories database from 2008-2018 for diagnoses of necrotizing fasciitis, cellulitis, and stasis dermatitis, yielding 103 cases. Diagnoses were verified by chart review and categorized by discharge diagnosis. Three samples from each category, along with three controls from location-matched skin were selected for further study. mRNA isolated from paraffin-embedded skin biopsies was analyzed by Nanostring, with 594 inflammatory genes profiled.
Results: We identified differentially expressed genes between necrotizing fasciitis, cellulitis, and infectious cases (necrotizing fasciitis and cellulitis) compared to non-infectious stasis dermatitis. Differentially upregulated genes in SSTIs included those with known roles in inflammation (CXCR2, IL6, IFI16, TNFRSF1B) and transcriptional regulation (BCL3, MBP). We also identified differential upregulation of genes not previously associated with SSTIs including S100A8, S100A9, MCL1, CD14, and LTF.
Conclusions: We characterized transcriptomic signatures of severe and moderate SSTIs compared to stasis dermatitis and normal skin from the lower extremities. Though limited by small sample size, these data support the utility of a prospective study analyzing outcomes of patients diagnosed with SSTIs based on gene expression signatures. Identifying SSTI-specific gene expression signatures could help differentiate true skin infections from non-infectious inflammatory skin conditions, facilitating more accurate diagnoses and improving patient care.
NEW FORMAT OF THE UNIFIED STATE EXAM (BY THE EXAMPLE OF THE FRENCH LANGUAGE)
Authors: Григорьева Елена Яковлевна , Горбачева Екатерина Юрьевна 
Published: November 2022

Проанализированы контрольные измерительные материалы российского единого государственного экзамена по французскому языку. Приведены примеры обновленных коммуникативных заданий, структура и содержание самого экзамена. Особое внимание уделяется изменениям, которые были внесены в разделы «Письмо» и «Говорение» экзаменационной работы 2022 года как на базовом, так и на повышенном уровне. В связи с новыми заданиями соответствующие изменения внесены и в критерии оценивания. Описаны типичные ошибки, приводящие к сбою в коммуникации и искажению смысла.
The control measuring materials of the Russian unified state exam in French are analyzed. Examples of updated communicative tasks, the structure and content of the exam itself, its basic and advanced levels are givn. Particular attention is paid to the changes that have been made to the Writing and Speaking sections of the 2022 exam paper at both the basic and advanced levels. In connection with the new tasks, the corresponding changes were made to the assessment criteria. Typical mistakes are described that lead to a failure in communication and distortion of meaning.
DEVELOPMENT OF TEACHERS’ PROFESSIONAL COMPETENCE IN THE FIELD OF COMPREHENSIVE SUPPORT OF CHILDREN WITH DISABILITIES: ORGANIZATIONAL AND METHODOLOGICAL ASPECTS
Authors: Васильева Надежда Николаевна 
Published: November 2022

Рассмотрена проблема формирования профессиональной компетентности педагогов в области психолого-педагогического сопровождения детей с ограниченными возможностями здоровья (ОВЗ). В качестве методов исследования применены: изучение нормативно-правовых документов, регулирующих сферу образования; анализ современных тематических исследований; обобщение опыта подготовки педагогов и повышения их квалификации. Обозначены опорные точки модернизации теоретической и практической подготовки специалистов сопровождения детей с ОВЗ. Обсуждаются организационно-методические аспекты повышения профессиональной компетентности педагогов в сфере комплексного сопровождения детей с ОВЗ.
The article is devoted to the problem of formation of teachers’ professional competence teachers in the field of psychological and pedagogical support for children with disabilities. The following methods were used as research methods: the study of legal documents regulating the sphere of education; analysis of contemporary case studies and methods of teachers’ training. We indicate the key points for the modernization of the theoretical and practical training of specialists in accompanying children with disabilities. We also discuss organizational and methodological aspects of increasing teachers’ professional competence in the field of comprehensive support for children with disabilities.
THE LINGUOCULTUROLOGICAL ASPECT OF THE STUDY OF LANGUAGE UNITS IN TEACHING RUSSIAN AS A FOREIGN LANGUAGE
Authors: Парочкина Мария Михайловна , Воробьёва Галина Васильевна 
Published: November 2022

Уточнена специфика лингвострановедческого подхода к анализу иноязычного учебного текста, рассмотрены некоторые особенности методической работы с его лингвокультурными компонентами. Подчеркивается важность выделения в методике преподавания русского языка как иностранного отдельной дисциплины - лингвострановедения, ставящего своей задачей развитие коммуникативной компетенции иностранного учащегося посредством приобщения к культуре страны изучаемого языка. Объектом исследования в статье выступает лингвострановедческий аспект изучения языковых единиц в процессе обучения РКИ, предметом является система работы с лингвострановедческим аспектом текста. Освещаются ведущие принципы лингвострановедения, перечисляются основные языковые единицы, находящиеся в фокусе внимания лингвострановедения. Рассматриваются виды лингвокультурных лакун, а также процесс их элиминации.
The purpose of the article is to clarify the specifics of the linguoculturological approach to the analysis of a foreign-language educational text, to consider some features of methodological work with its linguistic and cultural components. The authors emphasize the importance of separating a separate discipline from the general regional studies - linguistic and regional studies, the main task of which is the development of communicative competence through familiarization with a culture. The object of research in the article is the linguoculturological aspect of the study of language units in the process of teaching Russian as a foreign language, the subject is the system of work with the linguistic and cultural aspect of the text. The authors of the article highlight the leading principles of linguoculturology, list the main linguistic units that are in the focus of linguoculturology. The article discusses the types of linguistic and cultural gaps, as well as the process of their elimination.
STUDENTS' COGNITIVE AND COGNITIVE ACTIVITY IN THE PROCESS OF LEARNING A FOREIGN LANGUAGE USING LEARNING ROBOTS
Authors: Ван Шисянь 
Published: November 2022

Анализируются актуальные исследования по изучению лексики, грамматики, чтения и аудирования на иностранных языках посредством образовательной робототехники. Рассмотрено влияние обучающих роботов на мотивацию учащихся, влияние новизны обучающих роботов на изучение иностранного языка и сложности социального поведения обучающих роботов. В итоге установлено, что содержание обучения с помощью роботов нацелено на активизацию познавательной деятельности учащихся и обладает значительным потенциалом для развития эмоциональных навыков, необходимых в процессе обучения.
Current research on the study of vocabulary, grammar, reading and listening in foreign languages through educational robotics is analyzed. The influence of teaching robots on the motivation of students, the impact of the novelty of teaching robots on learning a foreign language and the complexity of the social behavior of teaching robots are considered. Accordingly, it is discovered that robot-assisted learning content aims to stimulate students' cognitive functions and has a considerable potential for fostering the emotional abilities required for learning.