bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Leitura como Ação Formadora do Desenvolvimento Pessoal e Profissional do Indivíduo / Reading as an Action for the Formation of the Individual's Personal and Professional Development
Authors: Carvalho Ricardo Gondim de , França Aurenia Pereira de 
Published: January 2022

Resumo: Este artigo trata-se de uma pesquisa de caráter bibliográfico com o objetivo de analisar a importância da leitura para o desenvolvimento pessoal e profissional do indivíduo, bem como, descrever o conceito de leitura, apresentar a participação das instituições no fomento à leitura, e compreender a importância da leitura na construção do indivíduo. Apresenta a seguinte problemática: Qual a importância da leitura na construção pessoal e profissional do indivíduo? Para embasar a discussão foram consultados sites, artigos, dissertações e autores que discorrem sobre a temática em foco, entre eles destacam-se: Burke (2003), Silva (1991), Martins (1994), Freire (1989), Chartier (1990), Solé (1998), Weiers (2011). Com esse estudo espera-se ter êxito na análise da importância da leitura para o desenvolvimento do indivíduo pessoal e profissional. Com o intuito de aprender a ler e de ler para aprender considerando a capacidade de compreender e interpretar textos escritos como um instrumento necessário para atingir um desenvolvimento pleno, no contexto de uma sociedade letrada. Palavras-Chave: Leitura. Educação. Ensino-Aprendizagem. Abstract: This article is a bibliographic research with the objective of analyzing the importance of reading for the personal and professional development of the individual, as well as describing the concept of reading, presenting the participation of institutions in promoting reading, and understanding the importance of reading in the construction of the individual. It presents the following issue: What is the importance of reading in the individual's personal and professional construction? To support the discussion, websites, articles, dissertations and authors who discuss the topic in focus were consulted, including: Burke (2003), Silva (1991), Martins (1994), Freire (1989), Chartier (1990 ), Solé (1998), Weiers (2011). This study is expected to be successful in analyzing the importance of reading for the development of the personal and professional individual. In order to learn to read and to read to learn, consider the ability to understand and interpret written texts as a necessary instrument to achieve full development, in the context of a literate society. Keywords: Reading. Education. Teaching-Learning.
A Importância do Farmacêutico no Acompanhamento Farmacoterapêutico em Pacientes Idosos Polimedicados / The Importance of the Pharmacist in the Pharmacotherapeutic Follow-Up in Polymedicate Elderly Patients
Authors: Arruda Ariele Oliveira , Silva Luciene Rodrigues da , Malheiro Luciano Hasimoto 
Published: January 2022

Resumo: A atuação do profissional farmacêutico se tornou indispensável no cuidado com a saúde do idoso. principalmente na educação de um consumo de medicamentos consciente e seguro. Em decorrência do envelhecimento, o indivíduo se torna mais propenso a evoluções patológicas, e assim aumentando o consumo de medicamentos. Isso amplia as possibilidades de erros relacionados aos fármacos, como interações, reações adversas e incidentes relacionados a administração medicamentosa. Desta forma, o presente trabalho teve como objetivo realizar uma revisão integrativa sobre a importância do acompanhamento farmacêutico na promoção da qualidade de vida dos idosos polimedicados e detectar prováveis riscos relacionados ao uso de medicamentos. A metodologia empregada consiste em um estudo de pesquisa bibliográfica com abordagem integrativa. A busca pelas publicações foi realizada através das plataformas Biblioteca Virtual em Saúde (BVS), Pubmed, Google Acadêmico e Periódico CAPES. A literatura disponível indica que o farmacêutico possui papel fundamental na orientação medicamentosa do idoso polimedicado, garantindo um tratamento farmacoterapêutico mais eficaz e seguro, e assim proporcionando maior qualidade de vida durante o processo de envelhecimento.Palavras-chave: Automedicação; Polifarmácia; Uso Inadequado de medicamentos. Abstract: The role of the pharmacist has become essential in caring for the health of the elderly. mainly in the education of a conscious and safe consumption of medicines. As a result of aging, the individual becomes more prone to pathological developments, thus increasing the consumption of medications. This expands the possibilities of drug-related errors, such as interactions, adverse reactions and incidents related to drug administration. Thus, this study aimed to carry out an integrative review on the importance of pharmaceutical monitoring in promoting the quality of life of polymedicated elderly people and detecting probable risks related to the use of medication. The methodology used consists of a bibliographic research study with an integrative approach. The search for publications was performed using Biblioteca Virtual em Saúde (BVS), Pubmed, Google Scholar and Periódico CAPES. The available literature indicates that the pharmacist has a fundamental role in the medication guidance of the polymedicated elderly, ensuring a more effective and safer pharmacotherapeutic treatment, and thus providing a better quality of life during the aging process.Keywords: Inappropriate use of medications. Polypharmacy. Self-medication.
Encontros na Península, de Milton Hatoum: Um diálogo com A causa secreta, de Machado de Assis / Encontros na Península, by Milton Hatoum: A dialogue with the Secret Cause, by Machado de Assis
Authors: Ataíde Maria Betânia Da Costa , Amorim José Edilson De 
Published: January 2022

Resumo: Nesse artigo temos como objetivo apresentar uma leitura comparada do conto “Encontros na Península”, de Milton Hatoum com “A causa secreta”, de Machado de Assis. Ao longo do trabalho apresentamos algumas reflexões em torno da pergunta da personagem Victoria Soller. Teoricamente nos baseamos em Carvalhal (2004) com a obra Literatura Comparada, e em Bakhtin Dialogismo e Polifonia (2016). Notamos através das relações intertextuais que o conto “Encontros na Península” dialoga com alguns textos machadianos. Palavras-chave: Machado de Assis; Milton Hatoum; Literatura comparada. Abstract: In this article we aim to present a comparative reading of the short story “Encontros na Península”, by Milton Hatoum with “A causa secreta”, by Machado de Assis. Throughout the work, we present some reflections on the question of the character Victoria Soller. Theoretically, we are based on Carvalhal (2004) with the book Comparative Literature, and on Bakhtin Dialogismo e Polifonia (2016). Through the intertextual relationships, we noticed that the short story “Encontros na Península” dialogues with some Machadian texts. Keywords: Machado de Assis; Milton Hatoum; Comparative literature.
Inclusão do Aluno Autista na Escola: Um Olhar sobre a Mediação Pedagógica / Inclusion of the Autistic Student in School: A Look at Pedagogical Mediation
Authors: Araújo Iracelia Pereira Silva de , Menezes Aurelania Maria De Carvalho 
Published: January 2022

Resumo: Esse trabalho teve por objetivo apresentar uma abordagem geral dos pacientes autistas bem como, as características e dificuldades que são enfrentadas para a inclusão destes, no âmbito escolar. Para fundamentação da pesquisa, foram realizadas buscas nas bases de dados, usando as palavras-chaves: autismo, inclusão escolar, educação básica. Também foram realizadas leituras de aportes teóricos que ampliam e enriquecem a discussão da temática. A busca se deu através de artigos indexados nas plataformas de dados (Google acadêmico) e Biblioteca Virtual De Saúde (BVS) e SCIELO. Foi constatado que ainda existe uma larga escala de pessoas na sociedade, que precisam ter mais conhecimento acerca da síndrome para que desse modo, saibam lidar e possam entender o paciente autista, porque compreendendo é mais fácil a inclusão destes no meio social e escolar. Entender o comportamento de cada autista também favorece a melhor forma para desenvolvimentos de estratégias de ensinos que visem estimular a aprendizagem e o comportamento destes. Palavras-Chave: Autismo; Inclusão Escolar; Atenção Básica. --- Inclusion of the Autistic Student in School: A Look at Pedagogical Mediation Abstract: This work aimed to present a general approach to autistic patients as well as the characteristics and difficulties that are faced for their inclusion in the school environment. To support the research, searches were carried out in the databases, using the keywords: autism, school inclusion, basic education. There were also readings of theoretical contributions that broaden and enrich the discussion of the subject. The search was carried out through articles indexed in data platforms (academic Google) and Virtual Health Library (BVS) and SCIELO. It was found that there is still a large scale of people in society, who need to have more knowledge about the syndrome so that, in this way, they know how to deal with and can understand the autistic patient, because understanding their inclusion in the social and school environment is easier. Understanding the behavior of each autistic person also favors the best way to develop teaching strategies aimed at stimulating their learning and behavior. Keywords: Autism; School inclusion; Primary Care.
Educação e sua Importância no Processo de Inclusão de Crianças com TDAH: Inquietações a serem enfrentadas no Ensino Regular / Children with ADHD: Concerns to be Faced in Regular Education
Authors: Moura Eliane Da Silva Ferreira , Bezerra Fabiana Correia 
Published: January 2022

Resumo: O intuito da pesquisa foi conhecer a importância da educação de acordo com o processo de inclusão, o que afirmam os pesquisadores acerca do Transtorno de Déficit de Atenção e Hiperatividade (TDAH). Quanto ao processo metodológico, foi realizada pesquisa bibliográfica com abordagem qualitativa e estudo de caso com entrevista semiestruturada. Os efeitos apontaram as dificuldades de adaptação por conta da falta de qualificação específica dos professores no ensino regular, falta de conhecimento por parte das famílias, dificuldades de aprendizagens e deficiência quanto à equidade no ensino. Concluiu-se que a educação inclusiva ainda está se moldando e se adaptando, seja na sociedade ou nas políticas públicas. Ao mesmo tempo em que parte da dificuldade de aprendizagem desses alunos com necessidades especiais, é dos pais sem informação adequada e os profissionais da educação, como também a sociedade e a comunidades escolares sem nenhuma formação ou informações adequadas. Palavras-chave: Ensino-aprendizagem. Inclusão. Transtorno de Déficit de Atenção e Hiperatividade. Capacitação. __________________________ Abstract: The purpose of the research was to know the importance of education according to the inclusion process, which researchers claim about Attention Deficit Hyperactivity Disorder (ADHD). As for the methodological process, a bibliographical research was carried out with a qualitative approach and a case study with semi-structured interview. The effects pointed out the difficulties of adaptation due to the lack of specific qualification of teachers in regular education, lack of knowledge on the part of families, learning difficulties and deficiencies in terms of equity in education. It was concluded that inclusive education is still shaping and adapting, whether in society or in public policies. While part of the learning difficulty of these students with special needs is parents without adequate information and education professionals, as well as society and school communities without any training or adequate information. Keywords: Teaching-learning. Inclusion. Attention Deficit Hyperactivity Disorder. Training.
Huntington disease update: new insights into the role of repeat instability in disease pathogenesis
Authors: Arning Larissa , Nguyen Huu Phuc 
Published: January 2022

Abstract
The causative mutation for Huntington disease (HD), an expanded trinucleotide repeat sequence in the first exon of the huntingtin gene (HTT) is naturally polymorphic and inevitably associated with disease symptoms above 39 CAG repeats. Although symptomatic medical therapies for HD can improve the motor and non-motor symptoms for affected patients, these drugs do not stop the ongoing neurodegeneration and progression of the disease, which results in severe motor and cognitive disability and death. To date, there is still an urgent need for the development of effective disease‐modifying therapies to slow or even stop the progression of HD. The increasing ability to intervene directly at the roots of the disease, namely HTT transcription and translation of its mRNA, makes it necessary to understand the pathogenesis of HD as precisely as possible.
In addition to the long-postulated toxicity of the polyglutamine-expanded mutant HTT protein, there is increasing evidence that the CAG repeat-containing RNA might also be directly involved in toxicity. Recent studies have identified cis- (DNA repair genes) and trans- (loss/duplication of CAA interruption) acting variants as major modifiers of age at onset (AO) and disease progression. More and more extensive data indicate that somatic instability functions as a driver for AO as well as disease progression and severity, not only in HD but also in other polyglutamine diseases. Thus, somatic expansions of repetitive DNA sequences may be essential to promote respective repeat lengths to reach a threshold leading to the overt neurodegenerative symptoms of trinucleotide diseases. These findings support somatic expansion as a potential therapeutic target in HD and related repeat expansion disorders.
Suggested Method of Specimen Preparation for Triaxial Tests on Partially Saturated Sand
Authors: Zeybek Abdülhakim 
Published: January 2022

Abstract
In geotechnical engineering, triaxial testing is widely adopted to evaluate the mechanical behavior of sand. Methods of specimen preparation for triaxial tests on dry and completely saturated sand are well established in the literature, whereas very little guidance exists on the preparation of partially saturated sand at relatively high degrees of saturation (typically Sr &gt; 80 %). The purpose of this study is to elucidate the suitable method of specimen preparation for partially saturated sand using sodium percarbonate and investigate the effects of partial saturation on the undrained cyclic behavior of sand. Loosely and densely packed specimens are prepared in a dynamic triaxial apparatus through dry pluviation and tamping of sand. For tests on fully saturated sand, dry specimens are flushed with carbon dioxide and deaired water and saturated applying back pressure. For tests on partially saturated sand, sodium percarbonate is used in either fine powder or aqueous solution form to create oxygen bubbles in the voids, reducing the degree of saturation of specimens. The results suggest that not only the degree of saturation but also the way partially saturated specimens are prepared affects the liquefaction resistance. At the same level of saturation and principal stress difference, specimens prepared with the aqueous solution exhibit higher liquefaction resistance than those prepared with the powder. The solution of sodium percarbonate proves to be a more reliable and repeatable technique for preparing partially saturated triaxial specimens with relatively high degrees of saturation.
KCTD8 and KCTD12 Facilitate Axonal Expression of GABABReceptors in Habenula Cholinergic Neurons
Authors: Ren Yuqi , Liu Yang , Zheng Sanduo , Luo Minmin 
Published: January 2022

GABABreceptors in habenula cholinergic neurons mediate strong presynaptic excitation and control aversive memory expression. K+channel tetramerization domain (KCTD) proteins are key interacting partners of GABABreceptors; it remains unclear whether and how KCTDs contribute to GABABexcitatory signaling. Here, we show that KCTD8 and KCTD12 in these neurons facilitate the GABABreceptors expression in axonal terminals and contribute to presynaptic excitation by GABABreceptors. Genetically knocking outKCTD8/12/16orKCTD8/12, but not other combinations of the threeKCTDisoforms, substantially reduced GABABreceptors–mediated potentiation of glutamate release and presynaptic Ca2+entry in response to axonal stimulation, whereas they had no effect on GABAB-mediated inhibition in the somata of cholinergic neurons within the habenulo–interpeduncular pathway in mice of either sex. The physiological phenotypes were associated with a significant decrease in the GABABexpression within the axonal terminals but not the somata. Overexpressing either KCTD8 or KCTD12 in theKCTD8/12/16triple knock-out mice reversed the changes in axonal GABABexpression and presynaptic excitation. In mice lacking the KCTDs, aversion-predicting cues produced stronger neuronal activation in the interpeduncular nucleus, and the infusion of GABABagonist in this nucleus produced a weaker effect on fear extinction. Collectively, our results reveal isoform-specific roles of KCTD proteins in enriching the axonal expression of GABABreceptors, facilitating their presynaptic signaling, and modulating aversion-related memory processes.SIGNIFICANCE STATEMENTGABABreceptors represent the principal inhibitory neurotransmitter receptor, but they mediate strong presynaptic excitation in the habenulo–interpeduncular pathway and modulate aversion memory expression. KCTD proteins are integral constituents of GABABreceptors. By analyzing the physiological, neuroanatomical, and behavioral phenotypes of multiple KCTD knock-out mouse lines, we show that KCTD8 and KCTD12 facilitate the axonal expression and hence presynaptic excitation of GABABreceptors in habenula cholinergic neurons and control cued-aversion memory formation and expression in the habenulo–interpeduncular pathway. These results expand the physiological and behavioral functions of KCTDs in modulating the brain neural circuits.
ЗООГЕОГРАФІЧНА ХАРАКТЕРИСТИКА НАПІВТВЕРДОКРИЛИХ (HEMIPTERA: HETEROPTERA) УРБОЦЕНОЗІВ МІСТА ХАРКІВ
Authors: Fedyay I. O. , Markina T. Yu. 
Published: January 2022

Наведено зоогеографічну характеристику напівтвердокрилих урбоценозів м. Харків (Україна), що демонструє досить велику роздрібненість типів ареалів клопів на території міста. Це може бути пов’язано з мозаїчністю умов існування комах в різних біотопах, що сприяє підвищенню різноманіття видів клопів з різних зоогеографічних груп (підгруп). Загалом виділено 20 типів видових ареалів, об’єднаних в 12 секторних груп. Найбільшими (як за кількістю видів, так і за чисельністю) виявились представники транспалеарктичної (64 види), західно-палеарктичної (62), європейської (20) та голарктичної (18) груп ареалів. Інші групи включали від одного до трьох видів. Чотири види клопів мають позапалеарктичний тип поширення з космополітним, неарктичним (по одному виду) та субкосмополітним (два види) ареалами.
NEW RECORDS OF CERCERIS TUBERCULATA (VILLERS, 1787) (HYMENOPTERA: CRABRONIDAE) FROM UKRAINE, WITH NOTES ON ITS PARASITOIDS AND PREY
Authors: Martynova K. V. , Martynov A. V. 
Published: January 2022

Present paper reports observations on the digger wasp Cerceris tuberculata (Villers, 1787) (Hymenoptera: Crabronidae), listed in Red Data Book of Ukraine, its parasitoids and prey. The observations revealed two parasitoids associated with this wasp: a cuckoo wasp Hedychrum virens Dahlbom, 1845 (Chrysididae) and velvet ant Nemka viduata viduata (Pallas, 1773) (Mutillidae). The host-parasitoid association of this velvet ant and C. tuberculata is provided for the first time. Four species of weevils were registered as a prey of C. tuberculata, three of them are given for the first time herein. New records of the species from Zaporizhzhya and Kherson Regions are provided; the species is reported from Zaporizhzhia Region for the first time.
ДО 75-РІЧЧЯ ІНСТИТУТУ ЗАХИСТУ РОСЛИН НААН УКРАЇНИ. ЕНТОМОЛОГІЧНІ ШКОЛИ
Authors: Krut’ M. V. 
Published: January 2022

На різних етапах проведення наукових досліджень із вирішення найважливіших питань щодо захисту сільськогосподарських культур в Інституті захисту рослин НААН сформувалися ентомологічні школи. Учні академіка АН УРСР В.П. Поспєлова здійснювали комплекс робіт із вивчення патології комах з метою обґрунтування мікробіологічного й хімічного методу боротьби з шкідниками. Напрямом наукових досліджень школи доктора біологічних наук, професора М.А. Теленги було використання біологічних методів з обмеження чисельності шкідників сільгоспкультур. З його учнів М.П. Дядечко й В.П. Приставко створили свої наукові школи. Школу лісових ентомологів (Д.Ф. Руднєв та інші) очолював З.С. Голов’янко. В подальшому професор Д.Ф. Руднєв розробляв хімічний метод захисту рослин від шкідливих організмів, але знайшов йому альтернативу — використання стійких до шкідників сортів рослин. Його справу продовжили професори В.А. Санін і В.П. Смілянець. Плідно працювала школа академіка АН УРСР В.П. Васильєва, вагомим результатом досліджень якої є теоретично обґрунтована економічна доцільність застосування інсектицидів та розроблені основи інтегрованого захисту рослин. Професор Б.А. Арєшніков разом із учнями основну частину своєї діяльності присвятив роботі з наукового обґрунтування ефективного й екологічно безпечного захисту зернових культур від шкідників, особливо клопа шкідливої черепашки. Вчених-ентомологів підготували також доктори наук, професори В.Г. Долін (з питань прогнозування розвитку шкідників рослин та розробки ефективних захисних заходів), М.П. Секун (з токсикології пестицидів), В.М. Чайка (з прогнозу та екології) та кандидати біологічних наук Н.В. Лаппа (з мікробіологічного методу захисту рослин), В.П. Омелюта (з карантину рослин). Є в інституті й представники наукових шкіл академіка НААН В.П. Федоренка та професора С.О. Трибеля з напряму еколого-економічної оптимізації інтегрованого захисту рослин від шкідників.В певні періоди Є.В. Звєрезомб-Зубовський, В.П. Васильєв і В.Г. Долін очолювали Українське ентомологічне товариство. Нині президентом цієї громадської організації є В.П. Федоренко.
Commercial meat cuts hardness of dual-purpose cattle from Cundinamarca (Colombia) high tropics zone
Authors: Acosta Castellanos Natalie Tatiana , López Vargas Jairo Humberto , Restrepo Molina Diego Alonso , Afanador Tellez Germán 
Published: January 2022

Este estudio tuvo como objetivo determinar el efecto del biotipo, la edad al sacrificio, la condición sexual y el sistema de alimentación sobre la dureza de cuatro cortes comerciales: Lomo (Longissimus dorsi), Bota (Biceps femoris), Muchacho (Semitendinosus) y Paletero (Infraspinatus), provenientes de 50 bovinos pertenecientes a sistemas de doble propósito del trópico alto en el departamento de Cundinamarca, Colombia. Para la obtención de los valores en este atributo se emplearon los métodos de medición instrumental de fuerza de corte con cuchilla de Warner-Bratzler y la evaluación sensorial, cuya correlación fue del 71%. Esto permitió la elaboración de una escala de dureza en la cual los cortes Lomo y Paletero se ubicaron en la categoría de “suave” (blando) y se comportaron estadísticamente igual en ambos métodos de medición, mientras que los cortes Bota y Muchacho se ubicaron en la categoría de “medio” y tuvieron diferencias estadísticas de acuerdo con la percepción dada por el panel sensorial. Así mismo, los resultados obtenidos mostraron diferencias significativas entre los cortes, destacando al Paletero por su menor valor de dureza y comportamiento similar al Lomo. Efectos significativos sobre la dureza de la carne fueron encontrados para todos los factores a excepción de la edad, lo cual muestra la influencia que tienen estos y su manejo en finca sobre la calidad de la carne.