bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early phonological training preceding kindergarten training: effects on reading and spelling
Authors: Wolff Ulrika , Gustafsson Jan-Eric 
Published: March 2022

AbstractThis study examined the effects of early phonological training on emergent phonological and reading skills. Children (N = 364) were randomly assigned in small groups to a phonological training group (n = 117), or a control group (n = 247) including both a non-phonological training group and a non-trained control group. The phonological training began three years before the formal reading instruction starts in Sweden. It was carried out in two waves during six weeks at the age of 4, and during six weeks at the age of 5. All children, including the control children, received phonological training in kindergarten at the age of 6. Fluid intelligence (Gf) and phonological awareness at age 4 predicted phonological awareness at age 6 as well as reading related skills in grades 2 and 3. There were substantial main effects of the early phonological training on phonological skills and early reading skills. For all outcomes the training was, furthermore, most beneficial for children low on Gf, who are in the risk zone of developing reading difficulties.
Frequentist statistical inference without repeated sampling
Authors: Vos Paul , Holbert Don 
Published: March 2022

AbstractFrequentist inference typically is described in terms of hypothetical repeated sampling but there are advantages to an interpretation that uses a single random sample. Contemporary examples are given that indicate probabilities for random phenomena are interpreted as classical probabilities, and this interpretation of equally likely chance outcomes is applied to statistical inference using urn models. These are used to address Bayesian criticisms of frequentist methods. Recent descriptions of p-values, confidence intervals, and power are viewed through the lens of classical probability based on a single random sample from the population.
Mouth puffing phenomena of patients with obstructive sleep apnea when mouth-taped: device’s efficacy confirmed with physical video observation
Authors: Jau Je-Yang , Kuo Terry B. J. , Li Lieber P. H. , Chen Tien-Yu , Lai Chun-Ting , Huang Pin-Hsuan , Yang Cheryl C. H. 
Published: March 2022

Abstract

Purpose
This study aimed to design a device to monitor mouth puffing phenomena of patients with obstructive sleep apnea when mouth-taped and to employ video recording and computing algorithms to double-check and verify the efficacy of the device.

Methods
A mouth puffing detector (MPD) was developed, and a video camera was set to record the patients’ mouth puffing phenomena in order to make ensure the data obtained from the device was appropriate and valid. Ten patients were recruited and had polysomnography. A program written in Python was used to investigate the efficacy of the program’s algorithms and the relationship between variables in polysomnography (sleep stage, apnea-hypopnea index or AHI, oxygen-related variables) and mouth puffing signals (MPSs). The video recording was used to validate the program. Bland–Altman plot, correlations, independent sample t-test, and ANOVA were analyzed by SPSS 24.0.

Results
Patients were found to mouth puff when they sleep with their mouths taped. An MPD was able to detect the signals of mouth puffing. Mouth puffing signals were noted and categorized into four types of MPSs by our algorithms. MPSs were found to be significantly related to relative OSA indices. When all participants’ data were divided into minutes, intermittent mouth puffing (IMP) was found to be significantly different from non-mouth puffing in AHI, oxygen desaturation index (ODI), and time of oxygen saturation under 90% (T90) (AHI: 0.75 vs. 0.31; ODI: 0.75 vs. 0.30; T90: 5.52 vs. 1.25; p < 0.001). Participants with severe OSA showed a higher IMP percentage compared to participants with mild to moderate OSA and the control group (severe: 38%, mild-to-moderate: 65%, control: 95%; p < 0.001).

Conclusions
This study established a simple way to detect mouth puffing phenomena when patients were mouth-taped during sleep, and the signals were classified into four types of MPSs. We propose that MPSs obtained from patients wearing the MPD can be used as a complement for clinicians to evaluate OSA.
Thirty Years of Thermal Barrier Coatings (TBC), Photothermal and Thermographic Techniques: Best Practices and Lessons Learned
Authors: Cernuschi Federico , Bison Paolo 
Published: March 2022

AbstractWith the adoption of thermal barrier coatings (TBCs) to protect the hot parts of gas turbines at the end of the last century, the characterization of their thermophysical properties and the evaluation of their state of integrity has become necessary. That leads to the development and/or the adaptation of photothermal and thermographic techniques to meet the newly requirements that have emerged. Whereas this is not an all-encompassing review of all the literature on the subjects, this work summarizes the research and the development of techniques specifically aimed at measuring the thermophysical properties, the characterization of the microstructure and the identification of adhesion defects to the metal component of the TBCs. In the following, the best practices, the lessons learned, the successes and the defeats experienced along almost thirty years will be summarized.
Predictors of RBD progression and conversion to synucleinopathies
Authors: de Natale Edoardo Rosario , Wilson Heather , Politis Marios 
Published: March 2022

Abstract
Purpose of review
Rapid eye movement (REM) sleep behaviour disorder (RBD) is considered the expression of the initial neurodegenerative process underlying synucleinopathies and constitutes the most important marker of their prodromal phase. This article reviews recent research from longitudinal research studies in isolated RBD (iRBD) aiming to describe the most promising progression biomarkers of iRBD and to delineate the current knowledge on the level of prediction of future outcome in iRBD patients at diagnosis.

Recent findings
Longitudinal studies revealed the potential value of a variety of biomarkers, including clinical markers of motor, autonomic, cognitive, and olfactory symptoms, neurophysiological markers such as REM sleep without atonia and electroencephalography, genetic and epigenetic markers, cerebrospinal fluid and serum markers, and neuroimaging markers to track the progression and predict phenoconversion. To-date the most promising neuroimaging biomarker in iRBD to aid the prediction of phenoconversion is striatal presynaptic striatal dopaminergic dysfunction.

Summary
There is a variety of potential biomarkers for monitoring disease progression and predicting iRBD conversion into synucleinopathies. A combined multimodal biomarker model could offer a more sensitive and specific tool. Further longitudinal studies are warranted to iRBD as a high-risk population for early neuroprotective interventions and disease-modifying therapies.
Detection of Potential Microbial Contaminants and Their Toxins in Fermented Dairy Products: a Comprehensive Review
Authors: El-Sayed Alaa S. , Ibrahim Hany , Farag Mohamed A. 
Published: March 2022

Abstract
Fermented dairy products are dominant constituents of daily diets around the world due to their desired organoleptic properties, long shelf life, and high nutritional value. Probiotics are often incorporated into these products for their health and technological benefits. However, the safety and possible contamination of fermented dairy products during the manufacturing process could have significant deleterious health and economic impacts. Pathogenic microorganisms and toxins from different sources in fermented dairy products contribute to outbreaks and toxicity cases. Although the health and nutritional benefits of fermented dairy products have been extensively investigated, safety hazards due to contamination are relatively less explored. As a preventive measure, it is crucial to accurately identify and determine the associated microbiota or their toxins. It is noteworthy to highlight the importance of detecting not only the pathogenic microbiota but also their toxic metabolites so that putative outbreaks can thereby be prevented or detected even before they cause harmful effects to human health. In this context, this review focuses on describing techniques designed to detect potential contaminants; also, the advantages and disadvantages of these techniques were summarized. Moreover, this review compiles the most recent and efficient analytical methods for detecting microbial hazards and toxins in different fermented dairy products of different origins. Causative agents behind contamination incidences are also discussed briefly to aid in future prevention measures, as well as detection approaches and technologies employed. Such approach enables the elucidation of the best strategies to control contamination in fermented dairy product manufacturing processes.
Emergency Heart failure Mortality Risk Grade may help to reduce heart failure admissions
Authors: van Hattem N. E. , Beeres S. L. M. A. , Mertens B. J. A. , Antoni M. L. , Atsma D. E. , Schalij M. J. , den Haan M. C. 
Published: March 2022

Abstract
Introduction
Hospital admissions for heart failure (HF) are frequent and pose a heavy burden on health care resources. Currently, the decision to hospitalise is based on clinical judgement rather than on prognostic risk stratification. The Emergency Heart failure Mortality Risk Grade (EHMRG) was recently developed to identify high-risk HF patients in the emergency department (ED).

Objective
To assess the ability of the EHMRG to predict 30-day mortality in Dutch HF patients visiting the ED and to evaluate whether the EHMRG could help to reduce the number of hospital admissions for decompensated HF.

Methods
Patients visiting the ED for decompensated HF were included. The decision to hospitalise or discharge was based on clinical judgement. The EHMRG was calculated retrospectively. Based on their EHMRG, patients were stratified as very low risk, low risk, intermediate risk, high risk and very high risk.

Results
In 227 patients (age 73 ± 12 years, 69% male) 30-day mortality was 11%. Mortality differed significantly among the EHMRG risk groups at 7‑day (p = 0.012) and 30-day follow-up (p < 0.01). Based on clinical judgement, 76% of patients were hospitalised. If decision-making had been based on EHMRG, the hospitalisation rate could have been reduced to 66% (p < 0.01), particularly by reducing hospitalisations in patients at low risk of death. Mortality in discharged patients, whether the decision was based on EHMRG or clinical judgement, was 0%.

Conclusion
The EHMRG accurately differentiates between high- and low-risk decompensated HF patients visiting the ED, making it a promising tool to safely reduce the number of HF admissions.
Involvement of frontline clinicians in healthcare technology development: Lessons learned from a ventilator project
Authors: Lin Margaret Chen-Mei , Kim Tae-Ho , Kim Woo Soo , Hakanson Ingrid , Hussein Ali , Hung Lillian 
Published: March 2022

AbstractCo-development of healthcare technology with users helps produce user-friendly products, ensuring safe device usage and meeting patients’ needs. For developers considering healthcare innovations, engaging user experience can reduce production time and cost while maximizing device application. The purpose of this paper is to report lessons learned from the development of a 3D printed origami ventilator prototype in response to the rise of ventilator demand due to the Coronavirus disease (COVID-19) pandemic. We conducted focus groups with frontline clinicians working in an Intensive Care Unit of a large urban hospital in Vancouver, British Columbia, Canada. In the interdisciplinary focus groups, we identified challenges, practical tips about product development, the human needs of technology, and cross-discipline peer learning. The focus group discussions provide useful insight into the technology development for complex clinical contexts. Based on our experiences, we articulate five practical tips for co-development of healthcare technology - AGILE: Analyse users’ needs first, Gain insights into complex context, Involve users early and frequently, Lead with a prototype, and Educate and support. Through sharing the tips and lessons learned, we wish to emphasize the necessity of meaningful multi-disciplinary collaboration during healthcare technology development and promote the inclusion of frontline clinicians during these initiatives.
Mating behaviour of the large-head resin bee Heriades truncorum (Megachilidae: Osminii) suggests female plastic strategy in selection of a mating partner and male quality assessment
Authors: Boff Samuel 
Published: March 2022

AbstractBehavioural courtship display and size of males are two attributes often used by females to select a mating partner. According to sexual selection, such traits are of importance, because a bigger size male or males displaying a better courtship could enhance the possibility of females to transmit her genes to the following generations via her offspring. In Hymenoptera such as in solitary bees, it is known that females can assess male quality and add this information in the process of mating choice. In the current study, I describe aspects of pre-copulatory mating behaviour of males, male quality assessment and female choice in the large-headed resin bee Heriades truncorum (Hymenoptera: Megachilidae: Osminii). Males of Heriades truncorum perform thoracic vibration, fan their wings and lift upwards female’s abdomen to copulate. Couples engage in sideways rocking motion movement like a dance. Female selection of a partner was also found to be density dependent. In a pair situation (one female for one male), female copulate equally with males of all sizes and male mating effort enhanced the chance of successful copulation. In an environment with mating choices (one female for two males of different sizes), successful copulation was significantly more frequent for bigger size males. Female response to male mounting took place independently of the number of mating partners in the arena and did not impair mating. Additionally, size had no effect on male-male competition. Both results suggest mating success in Heriades truncorum rely on a female choice mechanism.
Aeroengine transient performance simulation integrated with generic heat soakage and tip clearance model
Authors: Li Z. , Li Y.-G. , Sampath S. 
Published: March 2022

AbstractThe simulations and assessment of transient performance of gas turbine engines during the conceptual and preliminary design stage may be conducted ignoring heat soakage and tip clearance variations due to lack of detailed geometrical and structural information. As a result, problems with transient performance stability may not be revealed correctly, and corresponding design iterations would be necessary and costly when those problems are revealed at a detailed design stage. To make an engine design more cost and time effective, it has become important to require better transient performance simulations during the conceptual and preliminary design stage considering all key impact factors such as fuel control schedule, rotor dynamics, inter-component volume effect as well as heat soakage and tip clearance variation effects. In this research, a novel transient performance simulation approach with generically simplified heat soakage and tip clearance models for major gas path components of gas turbine engines including compressors, turbines and combustors has been developed to support more realistic transient performance simulations of gas turbine engines at conceptual and preliminary design stages. Such heat soakage and tip clearance models only require thermodynamic design parameters as input, which is normally available during such design stages. The models have been implemented into in-house transient performance simulation software and applied to a model twin-spool turbojet engine to test their effectiveness. Comparisons between transient performance simulated with and without the heat soakage and tip clearance effects demonstrate that the results are promising. Although the introduced heat soakage and tip clearance models may not be as accurate as that using detailed component geometrical information, it is able to include the major heat soakage and tip clearance effects and make the transient performance simulations and analysis more realistic during conceptual and preliminary engine design stage.
Reduced-order model for efficient generation of a subsonic missile’s aerodynamic database
Authors: Sinha A. , Kumar R. , Umakant J. 
Published: March 2022

AbstractThis article reports on the development of a fast method for generating the aerodynamic database for subsonic flow over a missile. At present, this is typically achieved using RANS-based CFD, which is expensive for the complex missile geometries and the multiplicity of operating conditions to be evaluated. The presented reduced-order model (ROM) provides a reasonably accurate prediction of the aerodynamic coefficients of the missile (and, in fact, the full flow field around it) within half a minute. In particular, in the interpolative regime, prediction errors for all coefficients are typically less than 1% of their respective maximum values encountered in the database, with extrapolation incurring more error. The empirical approach ‘learns’ from the CFD solutions calculated for a few operating conditions, and then is able to make predictions for any other condition within a feasible set. The learning employs proper orthogonal decomposition (POD) to characterise the most important features of the flow. The prediction is posed as an optimisation problem that aims to find the flow solution as a linear combination of the above POD modes that minimises the residual of the governing equations. Innovations on the prevailing POD-ROM approach include novel implementation of boundary conditions, simplified computation of the aerodynamic coefficients, and a procedure for choosing modelling parameters based on extensive cross-validation. Challenges overcome in application to a problem of industrial relevance are discussed.
Transcendence between Expression and Secrecy: A Critical Cognitive Perspective on the Metaphorical Discourse of Yārsān Religion
Authors: Veisi Hasar Rahman , Rezania Kianoosh 
Published: March 2022

AbstractThis paper seeks to shed light on the metaphorical discourse of the secretive minority religion of Yārsān. Metaphor is demonstrated as a central rhetorical device, applied as a linguistic apparatus that serves the ideology of concealment. To express heterodox concepts, Yārsān texts principally employ two rhetorical devices, metaphor and lexical substitution. The metaphorical models objectively conceptualize highly abstract religious notions and serve to obscure heretical concepts that strongly vary from established orthodox beliefs. As for lexical substitution, the most frequent metaphorical models are verbalized using foreign loanwords that are not common in Kurdish dialects. Together, these strategies construct a highly puzzling and mysterious discourse that is too difficult for outsiders to unravel. It can be argued that the metaphorical discourse of Yārsān functions as an anti-language that effectively challenges the limitations of expression imposed by the orthodox mainstream in the medieval era. Yārsān followers are able to express non-expressible ideas and disguise them within complicated imageries.
Effects of spatial and temporal regulation of drip emitters and tube configurations on water productivity of juvenile macadamia trees in the tropics
Authors: Bhattarai Surya P. , Pendergast Lance , Shuyan Li , Midmore David J. 
Published: March 2022

SummaryMacadamia in Australia is traditionally grown in semi-arid climates with hot and humid summers and cool winters supporting rainfed cultivation. Recent industry expansion into more northern, drier production areas of Queensland, Australia, requires supplementary irrigation for successful macadamia production. However, ever-increasing demand for irrigation water in these areas is both competitive and regulated. Limited information is available to optimize water use efficiency for field-grown macadamia trees. We trialled a technique that employs specially designed drip tubes with push-in emitter plugs to close emitters so that transplanting can start with emitters closed distant from tree bases and open next to the trunks of each tree. Additional emitters are then gradually opened (i.e., plugs are removed) as tree canopy size increases over subsequent years. This technique was tested on single and double in-line irrigation tube configurations per row of macadamia. Temporal regulation of emitter closure significantly reduced irrigation input by 75, 50 and 25% in the first, second and third year of treatment. Hence, irrigation over the three-year establishment period was reduced to one-half that of the non-regulated crop. These early reductions of irrigation in juvenile trees had no significant negative effects on plant growth (height, canopy spread, leaf chlorophyll and leaf photosynthetic rates), nor on nut counts. Control of emitter discharge between the plants along the row in the earlier stage (i.e., before complete within-row canopy cover) also reduced weed growth between the trees in the row. Notable growth advantages of the single in-line over the double in-line tube configuration were evident, with a non-significant but sizeable benefit on nut counts too. Effects of the temporal regulation of emitters and of in-line tube configurations must be validated on cultivars with differing water requirements and for the longer-term reproductive performance and nut quality.
Language Skills and Stock Market Participation: Evidence From Immigrants
Authors: Gan Xu , Song Frank M. , Zhou Yang 
Published: March 2022

AbstractDo language skills affect investment decisions? This article addresses this question by identifying the effect of English proficiency on the stock market participation of immigrants in the United States and Australia. To establish causality, we construct an instrumental variable for English proficiency by exploiting the phenomenon that younger children acquire languages more easily than older children. We find that English proficiency has a significant positive effect on stock ownership among immigrants in both countries. Moreover, we provide evidence that a reduction in information costs and an increase in trust may serve as the mechanisms underlying the language ability effect.