bluuebunny/crossref_metadata_2025_split huggingface dataset:
Survival prognostic factors for differentiated thyroid cancer patients with pulmonary metastases: A systematic review and meta-analysis
Authors: Zhao Hao , Liu Chun-Hao , Cao Yue , Zhang Li-Yang , Zhao Ya , Liu Yue-Wu , Liu Hong-Feng , Lin Yan-Song , Li Xiao-Yi 
Published: December 2022

BackgroundThe prognostic factors for differentiated thyroid cancer (DTC) patients with pulmonary metastases (PM) remain scantly identified and analyzed. Therefore, this systematic review and meta-analysis were performed to identify and summarize the prognostic factors in adult DTC patients with PM to help distinguish patients with different prognoses and inform the rational treatment regimens.MethodWe performed a comprehensive search of the relevant studies published in the Cochrane Library, PubMed, Scopus, Embase, Wanfang database, VIP database, China National Knowledge Infrastructure, and Google Scholar from their inception until February 2021. The pooled hazard ratios (HR) for overall survival and/or progression-free survival (PFS) with 95% confidence intervals were applied to evaluate and identify the potential prognostic factors. Pooled OS at different time points were also calculated for the available data. A random-effects model was used in the meta-analysis.ResultsThe review and meta-analysis included 21 studies comprising 2722 DTC patients with PM. The prognostic factors for poor OS were: age over 40 years (HR=7.21, 95% confidence interval [CI] 1.52-34.10, P=0.01, N=788), age over 45 years (HR=2.18, 95% CI 1.26-3.77, P&lt;0.01, N=601), male gender (HR=1.01, 95% CI 1.01-1.19, P=0.03, N=1396), follicular subtype of thyroid cancer (HR=1.63, 95% CI 1.36-1.96, P&lt;0.01, N=2110), iodine non-avidity (HR=3.10, 95% CI 1.79-5.37, P&lt;0.01, N=646), and metastases to other organs (HR=3.18, 95% CI 2.43-4.16, P&lt;0.01, N=1713). Factors associated with poor PFS included age over 45 years (HR=3.85, 95% CI 1.29-11.47, P&lt;0.01, N=306), male gender (HR=1.36, 95% CI 1.06-1.75, P=0.02, N=546), iodine non-avidity (HR=2.93, 95% CI 2.18-3.95, P&lt;0.01, N=395), pulmonary metastatic nodule size over 10mm (HR=2.56, 95% CI 2.02-3.24, P&lt;0.01, N=513), and extra-thyroidal invasion (HR=2.05, 95% CI 1.15-3.67, P=0.02, N=271). The pooled 1, 3, 5, 10, 15, and 20-years OS were 95.24%, 88.46%, 78.36%, 64.86%, 56.57%, and 51.03%, respectively.ConclusionsThis review and meta-analysis identified the prognostic factors of DTC patients with PM. Notably, FTC, metastases to other organs, and iodine non-avidity were particularly associated with poor prognosis. The identified prognostic factors will help guide the clinical management of DTC patients with PM.Systematic review registrationhttps://inplasy.com/inplasy-2022-2-0026/, identifier (INPLASY202220026).
The role of grievance in fatal family violence and implications for the construct of lone actor grievance-fuelled violence
Authors: Cooper Alannah J. , Pathé Michele T. , McEwan Troy E. 
Published: December 2022

IntroductionThe concept of lone actor grievance fuelled violence assumes that homicides that occur in very different contexts can be thought about in a consistent manner because they share common motivations and resultant emotional states like resentment, outrage or revenge. Fatal family violence has been largely excluded from discussions of lone actor grievance-fuelled homicide, based on the assumption that it is conceptually different. This scoping review examines similarities and discrepancies between the characteristics and motivations of perpetrators of fatal family violence and those who have engaged in lone actor grievance-fuelled homicide outside the family context, and the relevance of the concept of grievance-fuelled violence to fatal family violence.MethodsThis study reviewed published case studies and case series, resulting in a dataset of 102 homicide cases from 36 studies, of which there were 38 fatal family violence cases and 64 categorised as lone actor grievance-fuelled homicide.ResultsTwenty of the 38 fatal family violence cases were identified as being grievance-fuelled, based on the presence of motivations consistent with definitions in the grievance literature. Whilst there were some offence similarities between the fatal family violence cases (e.g., location of offence), those driven by grievance were more similar to lone actor grievance-fuelled homicide in other ways (e.g., offender’s gender and offence methods). In both these categories violence was predominantly motivated by grievance and a desire for revenge, whereas non-grievance fatal family violence cases were predominantly motivated by altruism.DiscussionThe motivations that defined behaviour as lone actor grievance-fuelled homicide were equally apparent in a sub-group of fatal family violence, implying that some family violence cases can be integrated into the construct of lone actor grievance-fuelled homicide in future research and theorising.
Relationships between positive schemas and life satisfaction in psychiatric inpatients
Authors: Chi Danni , Zhong Haiyun , Wang Yubo , Ma Hong , Zhang Yuanyuan , Du Xiangju 
Published: December 2022

IntroductionUnlike the extensively examined early maladaptive schemas, positive schemas have rarely been examined in psychiatric patients. This study aimed to investigate the relationships between anxiety, depression, life satisfaction, resilience, and positive schemas in psychiatric inpatients with generalized anxiety disorder or major depressive disorder and explore their associations. A sample of 140 psychiatric inpatients with anxiety and depression, aged between 18 and 72 years (Mage = 35.62, SD = 13.87) participated in this study.MethodsA majority were women (n = 98, 70.0%). The analyses examined resilience and anxiety/depression as mediators between positive schema and life satisfaction.ResultsBased on statistical analyses, resilience and anxiety/depression were parallel rather than serial mediators between positive schemas and life satisfaction. These results confirmed the positive association between positive schemas and life satisfaction, and identified mechanisms between them: directly associated and indirectly associated through the parallel mediations of resilience and anxiety/depression.DiscussionThe findings of this study suggest that higher levels of positive schemas in psychiatric inpatients are associated with greater life satisfaction directly and through the mediation of reduced psychopathological emotions and increased resilience. Longitudinal studies are needed to explore the associations between positive schemas and negative and positive outcomes and the mechanisms underlying these associations in clinical populations.
Effect of the COVID-19 pandemic on the psychotropic drug consumption
Authors: Benistand Paul , Vorilhon Philippe , Laporte Catherine , Bouillon-Minois Jean-Baptiste , Brousse Georges , Bagheri Reza , Ugbolue Ukadike Chris , Baker Julien S. , Flaudias Valentin , Mulliez Aurélien , Dutheil Frédéric 
Published: December 2022

ImportanceAlthough the COVID-19 pandemic has had a negative impact on mental health, there is no comprehensive longitudinal study of the entire population of a country without selection bias.ObjectiveThe objective of this study was to evaluate the prescription of psychotropic drugs during the COVID-19 pandemic, using data from the French national health data system (SNDS).Design, settings, and participantsPrescriptions for psychotropic drugs (antidepressants, anxiolytics, hypnotics, and antipsychotics) from 1 January 2015 to 30 September 2021 were collected from administrative data provided by the SNDS. This database includes more than 99% of the French population, i.e., 67 million people. The data were analyzed using an interrupted time series analysis (ITSA) model.Main outcomes and measuresConsumption of psychotropic drugs was aggregated in months and expressed in number of boxes per thousand inhabitants.ResultsDuring the study period, more than 1.3 billion boxes of psychotropic medications were dispensed. Comparison of psychotropic drug dispensing before and after the pandemic showed a relative increase of 0.76 (95 CI 0.57 to 0.95, p&lt;0.001) boxes per month per thousand inhabitants, all classes of psychotropic drugs combined. Three classes saw their consumption increase in an almost similar proportion, respectively, by 0.23 (0.15 to 0.32, p&lt;0.001) boxes for antidepressants, 0.27 (0.20 to 0.34, p&lt;0.001) boxes for anxiolytics and 0.23 (0.17 to 0.30, p&lt;0.001) boxes for hypnotics. The change in antipsychotic consumption was very small, with an increase of 0.04 boxes (0.02 to 0.06, p = 0.001) per month per thousand population.Conclusion and relevanceThe COVID-19 pandemic had led to an increase in the consumption of psychotropic drugs, confirming the significant impact of the pandemic on the mental health of the general population.
Data mining for prediction and interpretation of bacterial population behavior in food
Authors: Hosoe Junpei , Sunagawa Junya , Nakaoka Shinji , Koseki Shige , Koyama Kento 
Published: December 2022

Although bacterial population behavior has been investigated in a variety of foods in the past 40 years, it is difficult to obtain desired information from the mere juxtaposition of experimental data. We predicted the changes in the number of bacteria and visualize the effects of pH, aw, and temperature using a data mining approach. Population growth and inactivation data on eight pathogenic and food spoilage bacteria under 5,025 environmental conditions were obtained from the ComBase database (www.combase.cc), including 15 food categories, and temperatures ranging from 0°C to 25°C. The eXtreme gradient boosting tree was used to predict population behavior. The root mean square error of the observed and predicted values was 1.23 log CFU/g. The data mining model extracted the growth inhibition for the investigated bacteria against aw, temperature, and pH using the SHapley Additive eXplanations value. A data mining approach provides information concerning bacterial population behavior and how food ecosystems affect bacterial growth and inactivation.
PEMBANGUNAN SISTEM INFORMASI INVENTARIS BARANG BERBASIS WEB DI MABARROH CAHAYA MEGAH
Authors: Muchosid Abdul , Saputra Senna Aria 
Published: December 2022

Sistem persediaan adalah sistem untuk mengetahui persediaan barang di suatu tempat. Sistem inventaris telah banyak digunakan atau dikembangkan di tempat dengan beragam teknologi dan sistem. Masalah dengan Mabarroh Cahaya Megah ini adalah tidak tersedianya sistem persediaan sehingga tidak dapat mengontrol stok barang yang tersedia. Oleh karena itu, pekerjaan praktis ini akan membangun sistem informasi sistem persediaan yang berbasis web, sehingga informasi tentang stok dapat diketahui secara jelas dan rinci. Sistem inventaris ini akan diterapkan menggunakan sistem online berbasis web.
Metode pengembangan sistem dalam aplikasi ini menggunakan metode waterfall yang terdiri dari enam tahap. Tahapan tersebut adalah Analisis dan Desain Sistem, analisis kebutuhan perangkat lunak, desain sistem, pengkodean, pengujian dan pemeliharaan sistem. Aplikasi ini dibangun menggunakan bahasa pemrograman PHP, MySQL DataBase. Sistem Inventaris ini dapat dimanfaatkan dengan beberapa fasilitas yang disediakan, yaitu melalui web
Pengenalan Proses Kehamilan dan Informasinya Dengan Menggunakan Augmented Reality di Lingkungan Masyarakat RW 04 Cikawao Bandung
Authors: Adler John , Agnia Futry D , Rahman Muhammad A.F 
Published: December 2022

Proses kehamilan dikenal sebagai perjalanan yang sangat panjang yang ditunggu-tunggu seorang ibu hingga bayinya lahir. Kesehatan ibu hamil saat proses kehamilan sangat mempengaruhi keberhasilannya. Mengetahui proses kehamilan merupakan hal terpenting yang harus diketahui ibu hamil tentang kehamilannya agar janin dalam kandungan dapat berkembang dengan baik. Seperti kita ketahui, media informasi edukasi tentang perkembangan janin biasanya tersedia di buku teks, artikel umum, dan website khusus ibu hamil. Namun, media informasi tersebut membuat tidak terlalu menarik karena terlalu banyak teks deskriptif dan kurangnya gambar. Hal ini membuat kesulitan bagi ibu-ibu PKK karena pada masa pandemi ini para ibu-ibu diharuskan menjalankan aktivitas yang baru. Teknologi dalam hal pemberian informasi serta pembelajaran telah berkembang dan tersedia sehingga dapat dinikmati dan dimanfaatkan oleh kalangan luas. Dengan menggunakan smartphone, akan memudahkan ibu-ibu memperoleh informasi termasuk ibu-ibu PKK yang mungkin masih awam terhadap teknologi. Untuk itu kita rancang sebuah aplikasi Smart Health Pregnancy (SmHP). SmHP ini menggunakan teknologi Augmented Reality yang dapat menampilkan bentuk janin secara 3D (Tiga Dimensi) bagi para ibu hamil lalu bisa disimulasikan pada dunia nyata. Dengan menggunakan aplikasi yang telah dibuat untuk Ibu-Ibu PKK RW 04 di daerah Cikawao, diharapkan pelatihan pengabdian penggunaan aplikasi SmHP dapat memberikan kemudahan kepada ibu-ibu hamil di usia kandungan 1 sampai 9 bulan, untuk mendapatkan informasi proses janin setiap bulan juga perkembangannya dalam kandungan.
Perancangan Alat Bantu Potong Roti di Pabrik Roti Sawargi Bandung
Authors: Robecca Julian , Santosa Alam , Anggraeni Perawati N , Febiola Sherent L , Fakhrullah Muhammad F 
Published: December 2022

Berdasarkan tema dari kegiatan yaitu perancangan alat bantu potong roti, tujuan dari kegiatan pada masyarakat ini adalah untuk mengurangi jumlah roti sisa hasil potong sehingga jumlah kapasitas produksi roti bertambah dan jumlah roti yang layak jualpun bertambah. Selain itu mitra dalam hal ini adalah Pabrik Roti Sawargi dapat menerapkan pengetahuan yang didapat selama kegiatan dalam mengendalikan kualitas produk dan meningkatkan kapasitas produknya. Metode yang diterapkan pada kegiatan ini adalah metode diskusi interaktif dan metode demonstrasi. Metode diskusi interaktif digunakan untuk menyampaikan tentang manfaat, fungsi, bagaimana cara mengendalikan kualitas roti, memberikan kesempatan menyampaikan pendapat atau masukan dalam perancangan alat bantu potong yang akan dibuat. Metode demonstrasi digunakan untuk memperlihatkan cara penggunaan alat bantu potong dan dampak yang dihasilkan dari proses potong tersebut. Setelah dilakukan uji coba alat, baik oleh tim pelaksana PPM maupun oleh operator potong roti pabrik, masih perlu dilakukan beberapa tindakan agar dapat mengevaluasi efektifitas penggunaan alat dan penyempurnaan alat agar tujuan tercapai. Dengan adanya alat bantu potong roti yang baru ini diharapkan dapat mengurangi jumlah ketidaksesuaian dari roti yang dihasilkan seperti pinggiran roti besar, dimensi yang tidak sesuai, visual roti tidak baik, pinggiran roti kecil. Dengan berkurangnya jumlah ketidaksesuaian maka akan bertambah jumlah roti yang layak untuk dijual ke konsumen.
Penerapan Program Keselamatan dan Kesehatan Kerja di PT. Cibalung Sumberdaya
Authors: Aryantha I Made , Pamungkas Tri Noor 
Published: December 2022

Keselamatan dan Kesehatan Kerja, atau disingkat K3, adalah program negara. Program ini muncul dari keprihatinan atas banyaknya kecelakaan kerja yang menyebabkan penderitaan bagi pekerja dan keluarganya. Karena insiden cedera di tempat kerja tidak terlalu tinggi, program ini diremehkan oleh banyak orang. Kesehatan yang baik adalah potensi keproduktifan kerja yang baik. Oleh sebab itu pada momen kegiatan pengabdian masyarakat ini bertujuan untuk mengidentifikasi faktor penyebab kecelakaan saat bekerja menggunakan metode diagram fishbone di PT. Cibaliung Sumberdaya dan saran perbaikan untuk penerapan K3 di PT. Cibaliung Sumberdaya sehingga pada akhirnya kita mendapatkan hasil dari faktor – faktor penyebab kecelakaan dan saran perbaikannya. Berdasarkan hasil pengamatan terdapat 2 kasus kecelakaan kerja. Terdapat 3 faktor penyebab kecelakaan kerja pada fishbone diagram yang telah dibuat, pada kasus terjepit yaitu faktor manpower, faktor material dan faktor environment. Dan pada kasus terkena percikan dan asap las yaitu faktor manpower, faktor environment dan faktor machine. Teknis pelaksanaan kegiatan pengabdian masyarakat dengan menggunakan beberapa metode yaitu: observasi lapangan dan pengumpulan data, pengolahan data dan analisis. Kegiatan Pengabdian Kepada masyarakat ini memberikan kesadaran dan pemahaman tentang pentingnya Keselamatan dan Kesehatan kerja dalam bekerja.
Persilangan antara Iman dan Ilmu dalam Pandangan Jemaat tentang Kerasukan Roh dan Eksorsisme di GKI Gejayan
Authors: Widhiastuty Ratna Indah , Setio Robert 
Published: December 2022

Kerasukan dan eksorsisme merupakan fenomena yang lekat dengan kehidupan masyarakat (Indonesia). Sebagai bagian dari masyarakat, gereja juga tidak asing dengan fenomena tersebut. Tulisan ini akan mengangkat bagaimana sebuah gereja, dalam hal ini, Gereja Kristen Indonesia (GKI) Gejayan, Yogyakarta menanggapi fenomena tersebut. Pertanyaan penelitian yang diajukan dalam tulisan ini adalah bagaimana tanggapan terhadap kerasukan dan eksorsisme di GKI Gejayan memperlihatkan kedudukan dari ilmu pengetahuan dan iman di mata jemaat. Penelitian yang digunakan oleh penulis adalah penelitian kualitatif dengan menggunakan metode wawancara secara tertutup dan terbuka. Wawancara tertutup berupa pertanyaan-pertanyaan yang disodorkan kepada para peserta wawancara. Sedangkan wawancara terbuka dilakukan dengan mendalami lebih jauh jawaban atau tanggapan peserta untuk mendapatkan poin-poin yang masih belum muncul dalam pertanyaan-pertanyaan yang diajukan. Temuan yang diperoleh adalah dalam menghadapi kerasukan dan eksorsisme diperlukan kombinasi pendekatan antara iman dan ilmu.
Peran Guru Sekolah Minggu terhadap Pendidikan Seks bagi Anak Sekolah Minggu Usia Dini
Authors: Simanjuntak Elista , Prayitno Iky Sumarthina Putri 
Published: December 2022

Penelitian ini dilatarbelakangi adanya fenomena kekerasan seksual terhadap anak di daerah Kabupaten Tapanuli Utara, Sumatera Utara. Penelitian ini merupakan jenis penelitian deskriptif kualitatif dengan pendekatan studi pustakaan dengan menggambarkan peran guru Sekolah Minggu terhadap pendidikan seks sejak usia dini bagi naradidik. Metode pengumpulan data yang digunakan adalah teknik wawancara dan observasi dengan menggunakan analisis teori pendidikan kaum tertindas. Adapun hasilnya bahwa anak Sekolah Minggu mampu mengenal, memahami tentang masalah seksual, Sekolah Minggu mampu mengenal identitas dirinya sendiri sejak usia dini dengan meningkatkan spiritualitas terhadap Allah dan sesama, Sekolah Minggu mampu menjadi generasi pemutus rantai kekerasan seksual sejak usia dini. Tujuan penelitian ini untuk mencegah adanya kekerasan seksual bagi anak dan mencegah agar anak sejak usia dini tidak menjadi korban kekerasan seksual. Sehingga peran penting dari guru Sekolah Minggu sangat berperan dalam melindungi, mendidik dan membina anak dalam membentuk identitas karakter Kristus dalam dirinya yang memiliki cinta kasih terhadap Allah dan sesama.
Síndrome de Microdeleção 8q21.11: um relato de caso e seu seguimento no Brasil
Authors: Veado Marília Vilela , Leite Monica Ferreira 
Published: December 2022

A síndrome da microdeleção 8q21.11 é rara, ocorre por perdas cromossômicas detectadas por array genômico, sendo essencial o conhecimento dos fenótipos para solicitar investigação molecular. Este trabalho tem a finalidade de informar sobre esta microdeleção. Será relatado o caso de um portador da síndrome. Comparativamente aos demais reportados, o paciente possui muitas características concordantes. Após diagnóstico e início das intervenções terapêuticas houve melhora rápida no desenvolvimento. Após 5 meses de terapia evoluiu quanto a hipotonia e percepção do ambiente; iniciou comunicação sonora com balbucio de sílabas, apoio de joelhos e locomoção. Aos 8 anos de idade mantém estimulação e adquiriu marcos importantes como, caminhar e correr sem apoio, se alimenta sozinho, tem boa interação social, forma frases completas. TCM foi diagnosticado aos 18 meses, houve atraso na identificação dos fenótipos pela puericultura e após encaminhamento para especialista, o diagnóstico de outras síndromes genéticas até o diagnóstico final ser confirmado por array genômico. A falta de investigação molecular aprofundada e a não suspeição precoce das microdeleções leva ao atraso do diagnóstico e consequentemente, pior prognóstico. Sendo assim, faz-se necessário a propagação de informações sobre alterações moleculares e cromossomopatias raras.
Special physical fitness factors of athletes involved in pole sports
Authors: Sobko Iryna , Velieva Anastasia , Sobko Yana , Slastina Olena 
Published: December 2022

Purpose: to determine the peculiarities of training female athletes engaged in Pole Sports on the basis of the factor analysis of physical, special physical qualities and functional capabilities.
Material and methods: the study involved 15 female athletes (age 12-13 years), who are engaged in the sports club "Atmosphere" in Pole Sport and aerial acrobatics, Kharkov. Athletes are in the group of initial training (amateur level) and have the experience of sports activity 1-1,5 years. The study was conducted in September 2021. All participants and their parents agreed to participate in the experiment. Methods: theoretical analysis of literary sources; methods of testing physical development (height, weight); physical fitness (Push-ups 30 s, jumping rope for 3 min, lifting the trunk in sitting position in 1 minute, dynamometry of right and left arms, tilt of the body forward from the sitting position); special physical condition (chopper, pulling up on the pole, jumping rope for 3 min, jumping " Heels back", jumps with turning 180°, jumps with turning 360°, jumping into grouping); methods of functional capabilities (Genchi and Ruffier tests), mathematical and statistical methods using "EXCEL" and "SPSS" computer programs (factor analysis by principal component method was used). Results. A factor analysis of physical development indicators, physical training, functional athletes specializing in Pole Sport. It was found that in the structure of preparation of the athletes of this group overcomes the first factor "Special endurance" (15,21% of the total total dispersion), then the second "Functional abilities" (14,54% of the total total dispersion), the third factor "Power capabilities" (14,12% of the total cumulative variance) and the fourth factor " Coordination abilities" (14,02% of the total cumulative variance), the fifth factor " Flexibility " (13,52% of the total cumulative variance), the sixth factor "Technical capabilities" (12.37% of the total cumulative variance). The percentage contribution of these factors indicates the equivalent importance of these factors.
Conclusions. The training means for the development of special physical qualities and techniques, the dosage of the volume and intensity of loads for athletes 12-13 years old involved in Pole Sports are presented.
Analisis Faktor Yang Mempengaruhi Penyerapan Anggaran Pada Pemerintah Daerah Kabupaten Bengkalis
Authors: Kennedy Kennedy , Azlina Nur , Julita Julita , Nurulita Suci 
Published: December 2022

Abstract
This research aims to examine: the effect of budget planning, quality of human resources, organizational commitment, administrative records, and the government's internal control system on budget absorption. The population in this study was the regional apparatus organization in Bengkalis Regency, which amounted to 35 DPOs, consisting of 1 regional secretariat, 1 DPRD secretariat, 1 inspectorate, 1 civil service police unit, 1 hospital, 7 agencies, and 23 service offices. The method used is saturated sampling, with a total sample of 175 respondents. The data analysis method used in this study is SPSS version 23. The results of this study indicate that budget planning, quality of human resources, organizational commitment, administrative records and government internal control systems significantly influence budget absorption. The results of this research are expected to provide input to DPOs in Bengkalis Regency to take strategic steps in order to increase budget absorption in accordance with targets and regulation.
Keywords: Budget Absorption, Budget Planning, Quality of Human Resources, Organizational Commitment, Administrative Records, and Government Internal Control Systems.