bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hyperglycaemic Metabolic Complications of Ischemic Brain: Current
Therapeutics, Anti-Diabetics and Stem Cell Therapy
Authors: Chavda Vishal , Patel Snehal 
Published: June 2022

Abstract:
Stroke is the leading cause of morbidity and mortality in diabetic patients. Diabetes alters
the endothelial function and disrupts brain pathways, resulting in a variety of systemic metabolic complications.
Diabetics not only have impaired neurotransmission, but also have progressive neurodegeneration,
which leads to long-term neurological complications. Diabetes risk factors and physiology
alter the frequency and severity of cardiovascular and cerebrovascular events, necessitating more
hospitalizations. Stroke and diabetes have a mutually reinforcing relationship that worsens their outcomes.
Diabetes has far-reaching systemic consequences for human physiology as a metabolic syndrome.
As a result, diabetic stroke patients require dual-therapeutics with dual protection. Scientific
researchers have made tremendous progress in diabetes-related stroke and its therapeutics over the last
few decades. We have summarised diabetic brain and associated risk factors, co-morbidities, biomarkers,
and hyperglycemia-associated neurovascular insult and cognitive demur. In addition to
providing an overview of the effects of hyperglycaemia on brain physiology, this article aims to summarise
the evidence from current glucose-lowering treatment, recent advances in stroke therapeutics as
well as exploring stem cell therapy in the management of diabetes-associated stroke.
ENMSJ : An Efficiency Filtering Technique using Bitmap Vectors for n-way Joins in Wireless Sensor Networks
Authors: DJAIL Boubekeur 
Published: June 2022

In wireless sensor networks, join queries execution introduces a high energy consumption. While energy is an important factor for sensors survival, several techniques were developed to reduce it. Sensors energy is affected by the number of transferred messages whereas query is performed. The aim of the proposed techniques was then to decrease the communicated data volume. So, the exchanged data volume is soaring when joins are performed between many data tables. This joins type is called: n-way join query. In this paper, we present an efficiency technique to treat n-way join queries in wireless sensor networks. This technique is named: Enhanced N-way Mediated Semi-Join (ENMSJ). ENMSJ is an improvement of a precedent strategie that we proposed: N-way Mediated Semi-Join (NMSJ). ENMSJ uses bitmap tables to more reduce transferred messages quantity. We compared the two techniques to test their performance. Obtained results are very hopeful.
A mathematical model of PCNN for image fusion with non-sampled contourlet transform
Authors: Zhang Pai , Wang Lixia , Eslami Hayder 
Published: June 2022

Abstract
Non-sampled contourlet transform (NSCT) is a kind of non-down sampling image transformation, without spectrum aliasing, and the high-frequency region component can be further decomposed into various direction information, which has a good expression of image details. Therefore, this paper proposes an image fusion technology based on NSCT. Considering the different characteristics of low-frequency and high-frequency region components, the PCNN parallel method and ‘golden section method’ are used as double fusion rules, respectively in high- and low-frequency regions, whichperform the merge operation on the low area component. Experiments show that this algorithm has great advantages in preserving the details of image contour, texture and edge.
The Improvement of Tomato Shelf Life using Chitosan and Starfruit Leaf Extract as Edible Coatings
Authors: Utama Nafi Ananda , Ernawati Ririn , Pramesi Putrika Citta 
Published: June 2022

Abstract
Due to the high degree of perishability and vulnerability to spoilage, tomatoes have limited marketability, which leads to extensive postharvest losses. The edible coatings are generally used to extend the shelf life of fruits and vegetables; therefore, this study investigated the use of chitosan and starfruit leaf extract (SFLE) in the composition of edible coatings for tomato fruit. Firmness, total titratable acidity, reducing sugar content and microbial load were measured every 5 days for 25 days. The results showed that the addition of SLFE to chitosan did not enhance the antimicrobial effect or firmness over the effects made by a separate use of chitosan and SFLE. Both components improved the shelf life of tomato fruits compared to untreated tomatoes.
Implementasi 3-Axis Accelerometer Untuk Monitoring Lintasan Gerak Laju Roket
Authors: Fahriannur Ahmad , Zain Alex Taufiqurrohman 
Published: June 2022

Sistem ini terdiri atas 3-axis accelerometer MMA7260Q sebagai sensor percepatan, mikrokontroller, radio frekuensi, dan perangkat lunak penampil posisi muatan. Sistem melakukan pembacaan sinyal dengan waktu sampling 100ms. Data berupa posisi diperoleh dari hasil proses integral ganda terhadap keluaran accelerometer yang berupa percepatan (grativasi). Dari hasil pengujian, didapatkan bahwa sensor memiliki kesalahan pengukuran percepatan kurang dari 8%. Sistem secara keseluruhan dapat mengukur percepatan dan diubah kedalam bentuk jarak pada 3 sumbu dengan kesalahan pengukuran jarak 3,061% pada sumbu x dan 0,36% pada arah sumbu y, serta 1,023% pada arah sumbu z. Jarak tersebut ditampilkan pada Komputer dalam bentuk grafik 3 sumbu, sehingga akan tampil sebuah garis yang merepresentasikan posisi muatan roket.
Behavior of Square Footing Subjected to Gypseous Soil under Eccentricity-Inclined Load
Authors: Zedan Adnan J. , Husain Mazin Ali 
Published: June 2022

In this study, the behavior of square footing on gypsum soil is studied under inclined and eccentric loads via fabrication of a simulator of square footing (100 mm * 100 mm), fabrication of load tester and putting the soil in a box having a dimension of (900 mm * 900 mm * 600 mm). A sample of soil is taken from Tikrit University in Salah Al-Din province under 3 m depth which has a gypsum content of (50.48 %). The load test is performed on square footing at eccentricity of (e/B= 0, 0.1, 0.2 and 0.3) and an angle of inclination of the impacted load with the column ( i= 0°, 5°, 10°, 15°and 20°). The local specifications of the soil are measured (density, moisture, maximum density and ideal moisture), it is found that that the vertical falling, horizontal displacement, and base inclination increases with the increasing of eccentricity and inclination of impacted load, the soil resistance is less than the theoretical results for previous researchers in vertical load whereas it is approaching the theoretical results in inclined load. It is also observed that soil resistance decreases with the increasing of eccentricity of impacted load at local density and humidity, whereas it approaches the theoretical results at maximum density, ideal moisture, and vertical load conditions and gives results higher than that of theoretical analysis in inclined load where it decreases with increasing the eccentricity of impacted load. It is found that a high settlement occur in footing when a water (unsaturated with gypsum salts) diffuses through the soil, then gypsum become soluble thereby the soil resistance decreases because of rupturing of chemical bond between gypsum and soil.
Safety and efficacy of risuteganib ophthalmic solution in the treatment of dry eye disease: A prospective, randomized, double-masked, vehicle-controlled study
Authors: Donnenfeld Eric , Holland Edward , Lindstrom Richard , Karageozian Vicken , Park John , Shao Zixuan , Sarayba Melvin , Karageozian Lisa , Aubel Janine , Karageozian Hampar 
Published: June 2022

Objectives:
The aim of the study was to compare the safety and efficacy of ALG-1007 (0.125% sodium hyaluronate [SH] + 0.6% risuteganib [RSG] ophthalmic solution) to 0.6% RSG alone, 0.125% SH alone, and vehicle alone in subjects with dry eye disease (DED).

Material and Methods:
Eligible participants aged ≥18 years old with symptoms of DED for ≥ 6 months were randomized into four treatment groups: ALG-1007, RSG, SH, and vehicle. The treatment for all groups was administered one drop twice a day and subjects were evaluated at weeks 2, 4, 8, and 12. Primary efficacy endpoints were change in nasal conjunctival staining and change in Dry Eye Management Scale (DEMS) score from baseline to week 12. Secondary efficacy endpoints were changes in tear breakup time (TBUT), total ocular staining (TOS), inferior corneal staining score, and individual and combined reported symptoms by Visual Analog Scale (VAS), from baseline to week 12.

Results:
All parameters tested and analyzed – nasal conjunctival staining, DEMS, TBUT, inferior corneal staining score, and VAS (combined, burning, discomfort, dryness, foreign body sensation, and photophobia) – improved in all study groups over the 12-week observation period. The greatest improvements in all parameters tested were seen in the ALG-1007 group followed by RSG only, SH only, and then vehicle. Comparison of 12-week change from baseline (CFB) values demonstrated statistically significant differences in all group comparisons for all the measurements done except for comparison of ALG-1007 versus RSG (P = 0.3154) for nasal conjunctival staining. No adverse events were reported.

Conclusion:
0.60% RSG topical ophthalmic solution was effective in improving the signs and symptoms of DED and demonstrated therapeutic properties. ALG-1007, a combination of 0.60% RSG + 0.125% SH, was superior to RSG alone and will provide the most therapeutic benefit to patients with DED. ALG-1007 and RSG were well-tolerated with no drug-related AEs or SAEs reported over a 12-week observation period.
RANCANG BANGUN NASKAH LONTAR SEBAGAI SENI PERTUNJUKAN UNTUK SASTRA PARIWISATA
Authors: Agusman  , Azizurrohman Muhammad , Mashar  
Published: June 2022

Keberadaan naskah kuno dalam bentuk naskah lontar belum dijadikan sebagai bahan pengembangan pariwisata secara komprehensif. Hal tersebut tampak pada beberapa kegiatan pariwisata budaya yang masih kurang pemanfaatan naskah kuno khususnya naskah lontar. Dengan demikian, tulisan ini membahas tentang naskah lontar Lombok dari sisi rancang bangun sebagai seni pertunjukan untuk sastra pariwisata. Penelitian ini dilakukan di Lombok Tengah dengan dialek meriaq meriku, yaitu wilayah Pujut dan wilayah Bonjeruk (Jonggat) karena kedua daerah tersebut memiliki kebudayaan yang sama. Penelitian ini bersifat kualitatif dengan pendekatan etnografi dengan teknik wawancara yang ditujukan kepada tokoh adat dan budayawan. Data penelitian ini ialah deskrispsi naskah dan klasifikasi naskah berdasarkan tema yang profan dan sakral serta deskripsi mengenai rancang bangun naskah sebagai seni pertunjukan. Hasil penelitian menunjukkan terdapat 12 naskah (lontar) yang populer, yaitu Rengganis, Labang Kare, Madang Sekar, Bang Bari, Joharsah, Kayat Nabi, dan Junglengge yang diklasifikasikan sebagai naskah yang bersifat profan dan Indar Jaye, Jati Suare, Prudak Sine, Markum, dan Puspe Kerma sebagai naskah yang bersifat sakral. Naskah yang bersifat profan tersebut disusun dalam konsep rancang bangun seni pertunjukan dalam bentuk pertunjukan teater dengan mengambil cerita dari naskah lontar atau festival memaos naskah lontar. Konsep rancang bangun seni pertunjukan tersebut disusun menggunakan empat A, yaitu atraksi yang merujuk kepada atraksi atau kegiatan seni pertunjukan teaterdan memaos (membaca) naskah lontar, aksesibilitas yang merujuk kepada akomodasi dan cara operasional dari atraksi tersebut, amenitias yang merujuk kepada konsep pembentukan rasa kesenangan dan kenyamanan dalam konteks wisata dan layanan tambahan berupa kegiatan atau hal-hal kecil yang mendukung kegiatan atraksi sebagai komponen utama. Rancang bangun tersebut harus dilakukan dengan perencanaan dan penyusunan yang komprehensif agar SDA dan SDM bisa dimanfaatkan dengan baik menuju sastra untuk pariwisata budaya berkelanjutan.
MENGUNGKAP CITRA TRI RISMAHARINI SEBAGAI MENTERI SOSIAL DALAM BERITA ONLINE
Authors: Prasetiyo Anggik Budi 
Published: June 2022

Berita adalah salah satu media untuk merepresentasikan atau mencitrakan seseorang yang sedang diperbincangkan guna membangun asumsi di kalangan para pembaca. Tujuan penelitian ini adalah untuk mengungkap citra Tri Rismaharini (TR) yang dibentuk oleh Kompas.com dalam pemberitaan tentang penunjukan Menteri Sosial (Mensos) dalam reshuffle kabinet Indonesia Maju tahun 2020. Data dalam penelitian ini adalah kata, frasa, dan kalimat yang mengandung citraan TR sebagai Mensos. Sumber data penelitian ini adalah lima berita tentang penunjukan TR sebagai Mensos di laman Kompas.com. Penelitian ini termasuk dalam jenis penelitiam kualitatif dengan menggunakan metode deskriptif. Pendekatan yang digunakan dalam penelitian ini adalah analisis wacana kritis model Theo van Leeuwen. Hasil penelitian ini menunjukkan bahwa TR dicitrakan positif dengan menggunakan dua strategi, yaitu strategi inklusi dan strategi eksklusi. Strategi inklusi yang ditemukan ialah strategi inklusi diferensiasi, strategi inklusi kategorisasi, strategi inklusi abstraksi, dan strategi inklusi identifikasi, dan strategi inklusi asimilasi. Strategi eksklusi yang ditemukan ialah strategi eksklusi pasivasi dan strategi eksklusi nominalisasi.
PKM Pencegahan Penyebaran Covid Varian Omircon Dengan Pola Hidup Sehat Warga Desa Rowolaku Kabupaten Pekalongan
Authors: Kresnapati Pandu , Setiawan Danang Aji , Hadi Husnul 
Published: June 2022

Salah satunya negara yang mengalami dampak Covid 19 yakni Indonesia. Banyak kegiatan masyarakat yang dibatasi diantaranya sekolah, bekerja, berolahraga. Virus covid 19 varian terbaru omicron ditakutkan akan menyerang negara Indonesia yang biasa disebut gelombang ketiga. Masyarakat di desa Rowolaku sebagian besar dihuni oleh kaum anak-anak sampai lansia. Di era new normal ini masyarakat desa Rowolaku sudah melupakan mengenai penerapan protokol kesehatan, masyarakat beranggapan bahwa pendemi sudah berakhir terbukti sudah jarang penggunaan masker, menjaga jarak mencuci tangan dan penggunaan handsanitazer. Pola hidup sehat sudah tidak dipedulikan oleh masyarakat. Padahal berolahraga, makan teratur, menjaga kebersihan dan istirahat yang cukup, menerapkan protokol kesehatan merupakan unsur dalam pola hidup sehat di kala pandemi dan new normal untuk menjaga imunitas. Solusi yang ditawarkan pengabdi adalah dengan memberikan sosialisasi mengenai pencegahan covid 19 varian baru dan pembuatan handsanitazer. Pentingnya pengetahuan dan cara penanggulangan covid 19 gelombang ketiga dan varian baru. Target luaran yang nantinya dapat tercapai adalah masyarakat di desa Rowolaku bisa mengetahui dan melakukan pencegahan covid 19 gelombang ketiga sehingga dapat menciptakan hidup sehat dan terhindar dari virus corona. Tetap menerapkan protokol kesehatan untuk masyarakat desa Rowolaku secara mandiri di rumah masing-masing agar kesehatan dan imunitas semakin terjaga
Pelatihan Penjurian Senam Aerobik dan Senam Kreasi Bagi Instruktur Senam di Kabupaten Kendal
Authors: Fahmi Donny Anhar , Royana Ibnu Fatkhu , Herlambang Tubagus , Purwadi Purwadi 
Published: June 2022

Kabupaten Kendal merupakan kabupaten yang memiliki segudang sanggar senam. Sudah banyak instruktur-instruktur senam yang berdomisili dan menjadi instruktur di Instansi-instansi yang berada di Kabupaten Kendal. Namun dari banyaknya instruktur tersebut, ketika sedang perlombaan senam aerobik, penjurian atau yang menjadi juri masih mengundang dari luar Kabupaten Kendal. Oleh karena itu tim pengabdi memberikan pelatihan penjurian senam aerobic dan senam irama. Metode yang digunakan adalah pemberian materi ajar, pembekalan penjurian, dan praktek penjurian. Luaran dalam pengabdian ini adalah berupa pemberian sertifikat legal Kepada peserta sebagai penjuri yang dapat digunakan untuk syarat menjadi juri dalam perlombaan senam aerobic maupun senam irama.
Taylor’s University Graduate Research Symposium 2021
Authors: Chong Pei Pei , Farhadi Ali , Chantasart Doungdaw , Mah Siau Hui , Sellappans Renukha , Wong Eng Hwa , Behbahani Abbas Behzad , Safari Arash , Kalantari Tahereh , Suksiriworapong Jiraphong , Luangmonkong Theerut , Suriyaphan Orasa 
Published: June 2022

Graduate Research Symposium 2021 (GRS2021) was held virtually via Zoom on the 30th of November 2021. The theme of the symposium was Scientific Research Today: Borderless, Collaborative and Innovative. The symposium aimed to highlight the various types of scientific research being conducted by postgraduates from different international and local institutions to expand participants’ field of knowledge as well as encourage networking. GRS2021 covers a wide range of topics, which include natural products, drug discovery and formulation, life sciences, pharmaceutical sciences, medical sciences, food sciences and technology. This special issue exhibits the latest research findings by postgraduates from various scientific background. The emphasis is on studies that will contribute to the current knowledge and understanding in the targeted field of study.
Health facility practices and patterns of prescription influencing health-seeking behaviour among caregivers of children diagnosed with pneumonia in Endebess Sub-county, Kenya
Authors: Opuba Everlyne N. , Onyango Patrick O. 
Published: June 2022

Background Pneumonia accounts for 16% of all child deaths in Kenya, and it is the second killer of children under the age of five. Pneumonia burden is attributed to inadequate access to healthcare and poor health-seeking by caregivers. Endebess caregivers report delays of 1-14 days and subject their children to medicine from shops before visiting a hospital, as evidenced by the history of the presenting illness in patient files. In addition, irrational prescription has been demonstrated regardless of clinical guidelines. This study explored health facility practices and drug prescription patterns that influence health-seeking behaviour in Endebess Sub-county, Kenya. Methods A cross-sectional study involving 273 caregivers accompanied by a qualitative study on 24 health personnel was conducted from May to August 2019. Using a simple random sampling technique, a questionnaire was administered to caregivers visiting the health facilities. Key informant interview guides were also conducted with health care personnel. Quantitative data were analysed using logistic regression, whereas qualitative data were analysed by searching for emerging themes on health facility practices and prescription patterns across health facilities. Results Overall, stratification by health facility practices revealed that there were numerous significant results at the level of P<0.001, including the availability of drugs, administration of a starting dose, type of drug prescribed, willingness to recommend the facility, place caregiver seeks treatment (P=0.005) and facility of choice (P=0.001), which all influenced willingness to revisit the hospital. In relation to health information, the significant results at the level of P<0.001 included adequate instructions, the confidence of the caregiver to give the correct dosage at home, satisfaction levels and shared decision making on choices of antibiotic therapy (P=0.005) were associated with a higher willingness to revisit the hospital. There was a varied pattern of prescriptions for antibiotics. Consistently the odds of willingness to revisit the hospital increased among caregivers who had an injection medication prescribed for their children (P=0.380; odds ratio, OR=2.06, 95% confidence interval, CI=0.41-10.42) relative to those on oral medication. Conclusions There is a need for strict control of prescribing antibiotics in children under five years. Shared decision making on the choice of therapy should not be limited to chronic illnesses.
Effects of Anemia on Clinical Outcomes in Hospitalized Patients with COVID-19 Pneumonia
Authors: KURTOĞLU GÜMÜŞEL Hilal , GÖRMEZ Selçuk , ÖZÇAĞLAYAN Ömer , PAMUKÇU Burak 
Published: June 2022

Objective: We aimed to examine the role of anemia on clinical outcomes including intensive care unit (ICU) admission and mechanical ventilation (MV) in coronavirus disease 2019 (COVID-19) patients.
Materials and methods: Totally 175 hospitalized COVID-19 patients were retrospectively included. Patients with a hemoglobin level of
Деякі аспекти проблематики безальтернативності біосферосумісності людини
Authors: Маленко Я.В. 
Published: June 2022

За виразом видатного діяча, лауреата Нобелівської премії, володаря премії “Оскар” Дж. Бернарда Шоу «зараз, коли ми навчилися літати у повітрі як птахи, плавати під водою як риби, нам не вистачає лише єдиного: навчитися жити на Землі як люди». Людина постала у біосфері, живе у ній і не має іншої домівки. Вона виникла за законами біосфери і мусить жити за ними. Нерозуміння цього та небажання враховувати підстави нашого життя є основною причиною виникнення низки локальних та глобальних проблем, криз і катастроф, котрі ставлять під сумнів саму можливість безпечного існування людства. Наукові факти стверджують: упродовж величезного часу розвиток життя на Землі постійно зумовлювався і корелював зі змінами складу та структури біосфери, бо, як справедливо зазначав академік В.І. Вернадський, ні саме життя, ні еволюція його форм не можуть бути незалежними від біосфери, не можуть бути протиставлені їй як самостійні природні сутності.
Elaboración de torta de yacón para personas que tienen diabetes
Authors: Caicedo Figueroa Juan David , Jojoa Botina Diana Sofía 
Published: June 2022

Este proyecto empieza con el desarrollo de una idea que nace desde el análisis y puesta en marcha de un producto para las personas que sobrellevan la patología de la diabetes; así, surgió la necesidad de hacer una torta de yacón para esta población. Ahora bien, para la realización del prototipo, se analizó cómo se desarrollaría; fue así como se inició con la realización de un flujograma donde se escogió ciertos insumos, la realización del envase, empaque, marca y logotipo, piezas publicitarias, llevando de esta manera, los colores más propicios para los clientes. Se elaboró una segmentación psicográfica, demográfica y geográfica, dando como resultado, el número de personas que tienen diabetes, ya sea a nivel regional como internacional. Además, se tuvo en cuenta la realización de la matriz de preselección de mercados y la matriz PEST de diferentes países donde se analizó cada uno, de los cuales uno obtuvo una calificación meritoria para su proceso final de exportación: Estados Unidos. Posteriormente, también se tuvo en cuenta a ciertos proveedores que brindan la materia prima y los insumos necesarios para el avance del producto, los términos de negociación, parte fundamental al momento de exportar y, la ruta por la cual se enviará la mercancía bajo el sello de la aerolínea FEDEX, hasta el lugar de destino
La creatividad es el camino hacia la innovación
Authors: Gómez Ortega Jhesica Juliana , Prado Huaca Evelly Alejandra , Tutistar Hidalgo Lixi Juliana 
Published: June 2022

El emprendimiento nos invita a hacer realidad los sueños y metas que tenemos como personas y profesionales, siempre impulsados a mejorar nuestro bienestar económico y personal, buscando y generando nuevas oportunidades a personas de nuestro entorno. Cabe resaltar que todos los seres humanos somos creativos, el problema es que no sacamos esas ideas que llevamos por dentro, por miedo a fracasar; es importante entender que, ser un emprendedor es ser un líder que toma por iniciativa realizar actividades innovadoras con un objetivo claro; de igual manera, es una persona con actitud positiva, que siempre busca dar solución a ciertas problemáticas existentes.