bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of the diagnostic performance of the 1 mg dexamethasone suppression test in class 3 obese patients
Authors: Baldane Suleyman , Celik M , Kebapcilar Levent , Ipekci Suleyman Hilmi , Abusoglu Sedat , Yilmaz Huseyin , Alptekin Husnu 
Published: October 2022

Abstract

Objective. This study was aimed to evaluate the prevalence of Cushing’s syndrome and the diagnostic performance of the 1 mg dexamethasone suppression test in class 3 obese patients.

Methods. Anthropometric measurements and other laboratory data, including 1 mg dexamethasone suppression test of 753 class 3 obese patients, who applied to the Endocrinology and Metabolism Outpatient Clinic for the pre-bariatric surgery evaluation between 2011 and 2020, were evaluated retrospectively.

Results. An abnormal response to the 1 mg dexamethasone suppression test (cortisol ≥1.8 mcg/dl) was observed in 24 patients and the presence of Cushing’s syndrome was confirmed by additional tests in 6 patients. The prevalence of abnormal dexamethasone suppression test was 3.18% and the prevalence of Cushing’s syndrome 0.79%. The specificity value was determined as 97.5% for 1 mg dexamethasone suppression test with cortisol threshold value ≥1.8 mcg/dl.

Conclusions. The prevalence of Cushing’s syndrome was found to be low in class 3 obese patients and 1 mg of dexamethasone suppression test had a very sufficient performance for Cushing’s syndrome screening in this patient group.
Green Economic Development as the Framework for Green Finance and Green Investment
Authors: Vargas-Hernández José G. , Rakowska Joanna , Vargas-González Omar C. 
Published: October 2022

Abstract

Subject and purpose of work: This study aims to analyse the main elements of the green economic development as a framework for green finance and green investment. The analysis spurs from the underlying notion that green economics is inherently a normative framework and a school of thought development of the neo-classical economic thinking with conceptual assumptions, deficiencies, and contradictions, beginning to set out the roots, aims and philosophical principles.

Materials and methods: The methods used are the analytical and descriptive ones based on the critical literature review and an experiential reflective attitude on the key issues concerning the variables of green economic development, green finance, and green investment.

Conclusions: It is concluded that the implementation of green economy activities have many obstacles to face. The inadequate funding and the institutional support in collaborations and coordination practices are the most crucial.
Herding Behavior: Intensification and Flow in the Indonesian Stock Market
Authors: Hidayati Lina Nur , Alteza Muniya , Winarno Winarno 
Published: October 2022

Abstract

Subject and purpose of work: This paper explores whether herding behavior is formed according to the type of investor, how long the transmission of herding behavior occurs, and identifies how big the reaction of herding behavior is and how the flow of herding behavior connects between investors.

Materials and methods: The population in this study are companies whose shares are listed in the LQ45 index list for the period January 2015 to December 2017 on the Indonesia Stock Exchange. To find out further about herding behavior, a VAR test will be conducted in this study.

Results: The results of herding behavior analysis, based on the type of investor on the Indonesia Stock Exchange, show that there is herding behavior in each type of similar investor. Moreover, there is a certain period for the spread of herding behavior by type of shareholder.

Conclusions: The most influential variables on the four types of successive investors are domestic institutional investors, individual foreigners, domestic individuals, and foreign institutions. The four types of investors respond differently to herding behavior.
High DNAJA4 expression correlates with poor survival outcomes in breast cancer
Authors: Acun Tolga , Incekara Oya 
Published: October 2022

Abstract

Background: DNAJA4 (PRO1472) is a heat shock protein that has been associated with several types of cancers, including breast cancer. We aimed to reveal the protein expression, clinical outcomes, and regulatory mechanisms of DNAJA4 gene in breast cancer by employing tissue microarrays, transcriptomic datasets, and in-silico tools.

Methods: DNAJA4 protein expression and its clinical implications were evaluated by immunohistochemistry assay (normals = 32; tumors = 121). RNA-seq and DNA microarray datasets were analyzed by using breast cancer gene-expression miner (Bc-GenExMiner v4.8) to estimate the survival probabilities of breast cancer patients. DNAJA4 promoter methylation level was analyzed in clinical samples by UALCAN in-silico tool (normals = 97; tumors = 793).

Results: DNAJA4 protein expression is significantly high in clinical breast cancer samples compared to the normal samples (P = 0.016). High DNAJA4 mRNA expression is correlated with poor overall survival (OS), disease-free survival (DFS), and distant metastasis-free survival (DMFS) in breast cancer patients (P < 0.05). Mutations or copy number variations of DNAJA4 are uncommon in clinical samples. Reduced promoter methylation was observed in clinical breast cancer samples.

Conclusion: We suggest DNAJA4 expression as a new biomarker candidate for breast cancer. Promoter hypomethylation could be an important epigenetic factor in the upregulation of DNAJA4 expression in breast cancer.
التحليل الجغرافي لخصائص شبكة الطرق في مدينة عينكاوة باستخدام نظم المعلومات الجغرافية
Authors: Abdullah Sabah Othman 
Published: October 2022

تتناول هذه الدراسة خصائص شبكة الطرق في مدينة (عينكاوة) باستخدام تقنيات نظم المعلومات الجغرافية (GIS) وتحديداً من خلال برنامج (ARC MAP 10.8). وان الوصول بهذه الدراسة الى أهدافها التحليلية يجب دراسة واقع حال شبكات الطرق في منطقة الدراسة حيث بلغ اجمالي اطوال شبكة الطرق في مدينة عينكاوة ( 158 كم )، وتكون على ثلاث أصناف ( طرق محلية 129,4 كم ، طرقة رئيسية 18,6كم ، طرق سريعة 10كم ). وقد استخدمت أنواع كثيرة من أساليب والمعادلات للوصول الى درجة ترابط الشبكة، وان هذا الترابط يكون من خلال معرفة العلاقة بين عقد الشبكة و وصلاتها، هي تعطي تصور عن درجة ترابط الشبكة داخل المدينة، وقد بلغ عدد الوصلات في منطقة الدراسة (1811) وصلة، وعدد العقد بلغ (1170) عقدة. وفي هذه الدراسة حددنا أربعة أنواع من المؤشرات لمعرفة هذا الترابط وهي مؤشر (بيتا – جاما – الفا – قرينة الارتباط)، واظهرت ان شبكة الطرق في منطقة الدراسة يتضمن اكثر من شبكة مكتملة فيها ودرجة الترابط للشبكة ضعيفة. واستخدام أدوات داخل برنامج (ARC MAP 10.8) لتحليل شبكة النقل، مثل درجة المركزية للعقد ( المتوسط المكاني و الظاهرة المركزية و المسافة المعيارية )، وكذلك معرفة كثافة العقد، وكثافة الشبكة التي أظهرت النتيجة 15 كم طول الشبكة لكل كم2، وهي ذات كثافة عالية تفوق مثيلتها في الدول المتقدمة التي تبلغ في الغالب ( 10,7 ) كم /كم2 ،ومن الدول النامية التي تبلغ (4,3) كم / كم2(1).
جون ويكليف ودوره السياسي والفكري في إنكلترا (1320-1384)
Authors: Saeed Ibtisam Salman 
Published: October 2022

كان جون ويكليف من المصلحين ذوي المعرفة العلمية المتفحصة والمقام الخلقي الرفيع , وكانت آراؤه بمثابة حجر الاساس بالنسبة لحركة الاصلاح الديني , ليس في انكلترا فحسب , وانما في غرب أوربا بأكملها , فقد كان ويكليف رجل دين على قدر كبير من إستيعاب إصول الديانة المسيحية , هذا وقد ترقى في السلم الاكاديمي داخل جامعة أكسفورد , فقد عين عميدا لأقدم كلياتها , وشيئا" فشيئا" صار من المقربين لدى الملك ,حتى أصبح القسيس الخاص بالقصر الملكي وشجع كل ذلك جون ويكليف على الإقدام وإعلان آرائه على الملأ , وعلى الرغم من ميول آرائه ناحية السياسة العامة للدولة في بداية الأمر , إلا أنه في غالبية آرائه اتجه نحو الاصلاح الديني ,تأمل ويكليف أحوال الكنيسة من حوله , وما كانت تعانيه من فساد , وهداه عقله إلى إصدار مجموعة من المقالات والمواعظ التي تحتوي على كثير من السخط على رجال الدين , وانطبعت تلك المقالات بطابع من النزاهة والشجاعة , وجعلت من ويكليف طليعة من طلائع حرية الفكر وصراحة القول في إنكلترا , ولم تستهدف رسالة ويكليف طبقة المثقفين فحسب ,بل استهدفت سائر طبقات المجتمع , اذ نادى بأن تكون المواعظ الدينية والكتب المقدسة باللغة الإنكليزية لا اللاتينية , الامر الذي دفعه نحو تبني مشروع ترجمة الكتاب المقدس إلى اللغة الإنكليزية . من هنا يمكن القول ,إن تعاليم ويكليف كانت ملائمة للروح القومية الإنكليزية وفسر ذلك سرعة أنتشارها داخل الأوساط كافة في البلاد ,خاصة وهي معادية للبابوية , وكانت الأخيرة تحظى بعدم التأييد داخل البلاد , ومن ثم فهناك ترحيب لكل ما يكشف سياستها ويظهر وجهها الحقيقي , وجل الأمر إن حركة ويكليف حققت نتائج لابأس بها على مستويات عدة , ونقصد بذلك المستوى الحكومي والمستوى الشعبي والمستوى المذهبي وأخيرا المستوى الخارجي
أوحد الزمان أبو البركات الطبيب الفيلسوف
Authors: Thalnon Saad Abd Alhaleem , Hashem Muhammad Sagur 
Published: October 2022

وصلت العلوم العقلية والانسانية عند العرب والمسلمين وخصوصاً في العصر العباسي ، بسبب ما تميزت به تلك المرحلة من الانفتاح العلمي والحضاري ، ولم يكن العلم حكراً على المسلمين فقط بل شارك فيه اهل الملل الاخرى من يهود أو نصارى سواءً كانوا من العرب أو من غير العرب.
وأصبحت بغداد قبله العلماء والادباء والاطباء وطلبة العلم وغيرهم من اصحاب المهن والحرف ، ويعود الفضل في ذلك الى سعي الخلفاء العباسيين ومن سار على نهجهم من الامراء والوزراء برعاية العلماء وطلبة العلم والباحثين فيه ، وقد برزت شخصية الطبيب العراقي ابو البركات هبه الله بن ملكا اليهودي كطبيب بارع خدم الخليفة العباسي المستنجد بالله ( 518-566ه/1124-1170م)، وذاع صيته بين العامة ليس كطبيب فحسب بل كفيلسوف عظيم ، حتى عرف بأوحد زمانه وما يميز ابو البركات عن بقيه اطباء عصره انه عمل على العلاج للأمراض بالطب النفسي ونجح في شفاء العديد من المرضى معتمدا على حيل بسيطة غير انها قد أعطت نتائج كبيرة .
ذلك ما دعاني الى اظهار تلك الشخصية العلمية الكبيرة الذي ليس في مجال الطب فحسب بل في العلوم الاخرى فكان رفداً من روافد الحضارة العربية الاسلامية
Digitale Straßenmodelle
Authors: Nierenz Mirco 
Published: October 2022

Die Entwicklung im Bereich Autonomes Fahren erfordert zunehmend Testszenarien. Damit erhöht sich die Nachfrage nach Straßendaten. TrianGraphics hat neue Algorithmen und Verfahren entwickelt, um automatisch 3D-Straßennetze verknüpft mit Verkehrslogik und Umgebungsterrain zu erstellen.
Der Schwerpunkt der Forschungs- und Produktentwicklung wurde auf Straßengenerierung, basierend auf realen Daten mit einem möglichst hohen Automatisierungsgrad, gelegt. Der Artikel beschäftigt sich mit folgenden verschiedenen technischen Aspekte.
Bei Straßendaten werden zwei Arten unterstützt. SD-Daten mit Mittellinien und Attributen für Breiten, Fahrbahnanzahl und Straßentyp, sowie HD-Daten mit genauer Vektorbeschreibung jeder einzelnen Fahrspur. Es wird aufgezeigt, welche Formate dazu unterstützt werden, sowie deren Qualität und Verfügbarkeit.
Ein zweiter Schwerpunkt ist die automatische robuste Kreuzungserstellung. Die Konstruktion aus Realdaten stellt die Algorithmen vor Herausforderungen, da die Ausgangsdaten teilweise nur wenig geeignete Informationen bieten. Es wird die Erzeugung von Straßen und Kreuzungen skizziert, sowie Verkehrslogik-Formaten beschrieben. Der Fokus der Algorithmen liegt auf Robustheit, Genauigkeit und realistischen Ergebnissen. Weitere Metadaten wie Materialklassifizierung für die Sensorsimulation sowie Erkenntnisse aus der Automobilindustrie werden ebenfalls behandelt.
Eine weitere Besonderheit unseres Ansatzes ist die Bereitstellung und Generierung von Geländedaten. Neben der Straßengeometrie lässt sich die gesamte umgebende Landschaft virtuell abbilden. Ein reiches Set an Generierfeatures unterstützt dabei die Erzeugung/Platzierung von Vegetation, Gebäuden, Flüssen und weiteren Landschaftsobjekten. Die Landschaftsgeometrie kann in verschiedenen Datenformaten zur Verfügung gestellt werden.
Framework for Quantitative Digitalization Measurement in Supply Chain Planning
Authors: Wolf Maximilian , Puchan Jörg , Lauer Tim 
Published: October 2022

Measurement is a central element for any effective management. The megatrend of digitalization enables new possibilities, but also requires research on its appropriate monitoring considering digital transformation. In supply chain planning, todays methods are mostly qualitative. Thus, this study analyzes how the impact of digitalization can be quantified scoped to this field of application.
Based on the literature streams supply chain planning performance measurement, digitalization assessment and digital technologies the authors develop a holistic framework for quantitative digitalization measurement (QDMF). The framework comprises three dimensions: ‘Man’, ‘Technology’, and ‘Organization’. These itemize to 22 measurands specific to the context. The logic allows the comprehensive assessment of the effectiveness of digitalization projects and provides reliable, informative value for decision-making by the quantitative scaling. The framework is applied by conducting expert interviews for customization and data collection, whereon analytics calculates the measurands. In the end, experts interpret the results.
For verification and validation, the framework is deployed to the empirical use case of Infineon Technologies AG, Europe’s largest semiconductor manufacturer. The study concludes that quantitative digitalization monitoring is promising and can deliver new insights for effective managerial decision-making. Obstacles as limited data availability and constrained explanatory power are investigated and provide options for further studies.
Vergleichende Bewertung von Data-Warehouse-Landschaften in der Cloud am Beispiel von Microsoft Azure Synapse Analytics und Snowflake
Authors: Hua Thao-An , Ritz Harald , Myza Wadim 
Published: October 2022

Die Welt befindet sich in einem zunehmend rapiden gesellschaftlichen Wandel. Vieles soll schneller, virtueller und digitaler werden. Zur Entscheidungsunterstützung greifen viele Unternehmen auf Data-Warehouse-Landschaften in der Cloud zurück, um große Datenmengen zu analysieren. Die zentralen Merkmale des Cloud-Computings, wie die Skalierbarkeit, tragen zu einer effizienten Entscheidungsfindung bei.
Die adäquate Auswahl einer Cloud-Datenplattform-Lösung stellt eine Herausforderung für Unternehmen dar. Das Untersuchungsziel der Bachelorarbeit ist die Konzeption einer Bewertungsmatrix zur fundierten Auswahl einer Cloud-Datenplattform-Lösung. Am Beispiel der Gegenüberstellung des PaaS-Produkts Azure Synapse Analytics von Microsoft (MS) und des SaaS-Produkts Snowflake ist zu eruieren, welche Lösung in Bezug auf die beleuchteten Anforderungen am besten geeignet ist.
KEARIFAN LOKAL NELAYAN SUKU AKIT DI DESA TANJUNG KEDABU KECAMATAN RANGSANG PESISIR KABUPATEN KEPULAUAN MERANTI
Authors: Andini Fitri , Jalil Ashaluddin , Resdati Resdati 
Published: October 2022

This Study aims to determine the forms of local wisdom of the Akit Tribe fishermen and to find out equipment the Akit tribe fishermen use to catch fish in the Rangsang Pesisir District.The research method used is a qualitative method. Data were collected by observation and in-depth interviews, in addition to of course documentation. The results of the study found that there are several forms of local wisdom related to the activities of fishermen that still exist and live and are used in the life of the fishermen community. The local wisdom referred to include: First, the Bele Laut Ritual, which is an activity that aims to maintain or keep the sea still providing sustenance and safety for fishermen. The second ritual of getting off the boat is when buying a new boat is done as a form of gratitude for the fishermen for the new boat. Third, Determination of time, weather and seasons, the fishermen of the Akit Tribe believe in natural signs, such as when there are many stars at night, tomorrow the weather will be shady and sunny. Then they believed that the cloud that was scaly like fish in the afternoon was a sign that it was fish season. The meaning of maintaining ecology is when going to sea (netting, splinting) when the catches obtained by fishermen sort the fish, meaning that small fish that are considered unable or less useful are released into the sea. This clearly means that they have thought about the sustainability of animal life (sea) for the future or for their children and grandchildren who will become fishermen. The fishing activities of the Akit Tribe still use simple technology and equipment such as motorboats, oars and nets.
MODAL SOSIAL PELAKU USAHA IKAN BAKAR KAPIEK NDAK BATULANG DI DESA PULAU JAMBU KECAMATAN KUOK KABUPATEN KAMPAR
Authors: Handayani Suci Tri , Marnelly T. Romi , Resdati Resdati 
Published: October 2022

This research was conducted in Pulau Jambu Village, Kuok Subdistrict, Kampar Regency with the aim of knowing: 1) Elements of social capital and 2) Strategy in the Kapiek Ndak Batulang grilled fish business in Pulau Jambu Village. This research uses descriptive qualitative research method by taking 5 people as main informants and 1 people as key informants (Key Informants). This study uses purposive sampling technique through data collection techniques using observation, interviews, and documentation. The theory used is the theory of social capital. The results of research in the field can be concluded that there are 3 elements of social capital in the Kapiek Ndak Batulang grilled fish business in Pulau Jambu Village, namely network, trust, and social norms. Among these 3 elements each has a level of social capital, namely the strong, medium, and weak categories. Among the 3 most powerful elements of social capital is the element of trust social capital. This social capital is very very influential on fellow sellers, suppliers of Kapiek fish, customers/buyers, and employees. If social capital is strong, the benefits will be large. The results of the research regarding the strategy in the Kapiek Ndak Batulang grilled fish business there are 4 strategies, namely biological investment strategies, successive strategies, educational strategies, and economic investment strategies. Among the 4 strategies, the most dominant one used by business actors is the educational strategy. By always wanting to learn so that business actors can run their business well and survive until now.
TEACHER LEADERSHIP IN INCREASING THE EFFECTIVENESS OF SOCIOLOGY LEARNING
Authors: Widiansyah Subhan , Hardiansyah Muhammad Agus , Naim Mohammad 
Published: October 2022

This study aims to determine the leadership spirit of sociology teachers who are members of the Sociology Subject Teacher Consultation (MGMP) in Banten Province. Previous research has shown that students' motivation and learning achievement are highly dependent on the leadership spirit of teachers and teachers have a major role in shaping students' personalities. This shows that the teacher's leadership spirit affects students' learning motivation, and this leadership spirit has an important role for students to learn, work on, and complete school assignments. This research uses descriptive qualitative research methods which are carried out to members of the Sociology MGMP of Banten Province. This research will be a reference for sociology teachers in order to grow the leadership spirit of sociology teachers. This study uses descriptive qualitative research by interviewing sociology teachers and conducting Focus Group Discussions (FGD) to formulate effective leadership training for these teachers. Researchers facilitate and analyze the needs of sociology teachers in realizing effective sociology learning. Based on the results of the FGD and interviews, it was concluded that an effective teacher is a teacher who is able to adapt his leadership style to the situation and condition of the students. Teachers cannot only apply certain leadership patterns without paying attention to the needs of their students, effective teachers are adaptive teachers and can see situations and conditions when to be authoritarian and when to be democratic.
Peranan Sel Sistem Imun Alamiah Pada Infeksi Mycobacterium tuberculosis
Authors: Wijaya Chandra , Fatmawati Fatmawati 
Published: October 2022

Mycobacterium tuberculosis infection which causes tuberculosis is still a major health problem worldwide due to high morbidity and mortality, where in 2018 tuberculosis caused 1.5 million deaths. The degree of pulmonary tuberculosis varies from mild infiltration, chronic infection, cavity formation to severe and destructive tuberculosis. The difference in the degree of pulmonary tuberculosis is influenced by the response of the immune system to M. tuberculosis. When M. tuberculosis infects the lungs, the human immune system will carry out a series of processes to limit the spread and replication of bacteria. The immune system against M. tuberculosis consists of an innate immune system involving cellular components such as macrophages, neutrophils, Natural Killer (NK cells), dendritic cells and upper respiratory epithelium and an acquired immune response which is mainly mediated by T lymphocyte cells of host that is responsible for recognizing and controlling invasion by pathogens. This review will describe the role of natural immune system cells in M. tuberculosis infection. In addition, a complete description of M. tuberculosis infection will also be discussed to increase understanding of the role of natural immune system cells in M. tuberculosis infection.
На світлий спомин незникомого (пам’яті професора Єжи Бартмінського)
Authors: Богдан Світлана 
Published: October 2022

У статті розглянуто найважливіші сфери професійної наукової самореалізації одного з найвідоміших мовознавців кінця ХХ–початку ХХІ ст. Єжи Бартмінського – етнолінгвіста, фольклориста, діалектолога, славіста, праці якого визначили актуальні напрями наукових досліджень у вивченні мовних стереотипів і народних символів, що становлять основу мовної картини світу кожного етносу; проаналізовано також його роль у створенні лексикографічних праць нового типу й започаткуванні різних видавничих проєктів, зокрема щорічника «Етнолінгвістика» й збірника «Мова і культура».
Green Synthesis of IONPs for Photocatalytic Activities
Authors: A. Khamees Husam , A. Abid Muslim 
Published: October 2022

To make iron oxide nanoparticles (IONPs), a simple chemical approach was used to combine iron chloride (FeCl2+FeCl3) salt with onion peel extract. According to the study, iron salts can be converted into IONPs by the biomolecules in onion peel extract. From FeCl2+FeCl3 to γ -Fe2O3, the approach changes iron oxide NPs' size, shape, purity and phases. In water treatment, γ -Fe2O3 NPs are critical for the removal of the color methylene blue (MB). X-ray diffraction (XRD), scanning electron microscopy (SEM), ultraviolet (UV-Vis) and photoluminescence (PL) spectroscopy were used to identify IONPs. Results from the XRD experiment showed crystals having a tetragonal structure have average size of 13.4680 nm for γ- Fe2O3 NPs with a chemical method. Tetragonal diffraction peaks were observed in the data, and excellent crystal quality in a cubic shape. In the simple chemical process, the grain size was around (23.9 to 169.4) nm and average grain size 76.6 nm. UV-VIS measurements showed that the energy gap value had shifted to the blue from 1.94 to 2.96 eV in the simple chemical method.PL spectroscopy showed that the near band edge emission of γ-Fe2O3 NPs with a simple chemical approach was roughly 2.65 eV. NPs photocatalytic activity was as evidenced by the breakdown of MB dye when exposed to a moderate amount of light, as shown in this study. The results show that the synthesized material is of high quality γ-Fe2O3 NPs, with greater degrading efficiency when made using a simple chemical method, reaching 89.2% at 75 minutesfor 3 mg and 91.1% at 150 minutes for 5 mg, with a high level of photocatalytic efficacy the γ-Fe2O3.