bluuebunny/crossref_metadata_2025_split huggingface dataset:
Profile of uropathogens in pregnancy over 5 years from a large tertiary center in South India
Authors: David Liji Sarah , Varunashree N. D. , Ebenezer Emily Divya , Navaneethan Preethi Raja , Tirkey Richa Sasmita , Rathore Swati , Mahasampath Gowri , David Thambu , Mathews Jiji Elizabeth , Sahni Rani Diana 
Published: November 2022

Objectives:
Urinary tract infections (UTIs) are a common medical problem in both antenatal and postnatal women. Data from India on the demography of these women, microbiology and antimicrobial susceptibility of the causative bacteria, need elucidation.

Material and Methods:
We performed an observation study that collected data on UTI in antenatal and postnatal women between 2013 and 2017 at our tertiary care center in South India. Antenatally, urine dipstick-positive patients, high-risk, and symptomatic patients submitted urine cultures. Postnatally, all symptomatic patients had urine cultures. This was 20% of all antenatal and postnatal women resulting in 20,203 cultures.

Results:
Of 20,203 cultures, significant bacteriuria was seen in 9.48% of antenatal and 13.28% of postnatal women. A higher mean age was seen among those with UTI, antenatal 27 (SD 3.5) and postnatal 26.4 (SD 4.7) years versus 23.9 (SD 3.6) with no growth in culture. The mean BMI among antenatal was 28.2 (SD 3.5) and postnatal was 28 (SD 7.4). Most (60%) were primigravida. At delivery, 37% required cesarean sections while 21.2% required instrumental delivery. Recurrent UTI was seen in 25% antenatally and 10% in the postnatal period. Escherichia coli accounted for 66 and 60% of infections among antenatal and postnatal women, respectively. Enterococcus species accounted for 13% in both while Klebsiella species was 4.9 and 7.3%, respectively. Among E. coli, 68.3 and 59.2% of isolates in antenatal and postnatal period were cefpodoxime susceptible. Nearly 75% of ante- and postnatal isolates were susceptible to amoxicillin-clavulanate while 90.2% and 92.5% were susceptible to nitrofurantoin. Enterococci spp. up to 84.4 and 97.1% in ante- and postnatal isolates were susceptible to ampicillin, 64.4 and 77.4% susceptible to high-level gentamicin, and 84 and 95.5% susceptible to nitrofurantoin. Asymptomatic bacteriuria in pregnancy was documented in 2.1% of antenatal outpatients and E. coli was isolated in 74% of these cultures.

Conclusion:
Importance of microbiological evidence prior to administration of antimicrobials is evidenced by 79% negative cultures in this 5-year cohort. Escherichia coli accounted for 60-66% of significant bacteriuria followed by Enterococcus and Klebsiella species with 30-40% E.coli probable ESBL producers. Nitrofurantoin followed by amoxicillin-clavulanate were found to be the best oral antimicrobial options.
A scenario modelling analysis to anticipate the impact of COVID-19 vaccination in adolescents and children on disease outcomes in the Netherlands, summer 2021
Authors: Ainslie Kylie E C , Backer Jantien A , de Boer Pieter T , van Hoek Albert Jan , Klinkenberg Don , Korthals Altes Hester , Leung Ka Yin , de Melker Hester , Miura Fuminari , Wallinga Jacco 
Published: November 2022

Background
Since the roll-out of COVID-19 vaccines in late 2020 and throughout 2021, European governments have relied on mathematical modelling to inform policy decisions about COVID-19 vaccination.

Aim
We present a scenario-based modelling analysis in the Netherlands during summer 2021, to inform whether to extend vaccination to adolescents (12–17-year-olds) and children (5–11-year-olds).

Methods
We developed a deterministic, age-structured susceptible-exposed-infectious-recovered (SEIR) model and compared modelled incidences of infections, hospital and intensive care admissions, and deaths per 100,000 people across vaccination scenarios, before the emergence of the Omicron variant.

Results
Our model projections showed that, on average, upon the release of all non-pharmaceutical control measures on 1 November 2021, a large COVID-19 wave may occur in winter 2021/22, followed by a smaller, second wave in spring 2022, regardless of the vaccination scenario. The model projected reductions in infections/severe disease outcomes when vaccination was extended to adolescents and further reductions when vaccination was extended to all people over 5 years-old. When examining projected disease outcomes by age group, individuals benefitting most from extending vaccination were adolescents and children themselves. We also observed reductions in disease outcomes in older age groups, particularly of parent age (30–49 years), when children and adolescents were vaccinated, suggesting some prevention of onward transmission from younger to older age groups.

Conclusions
While our scenarios could not anticipate the emergence/consequences of SARS-CoV-2 Omicron variant, we illustrate how our approach can assist decision making. This could be useful when considering to provide booster doses or intervening against future infection waves.
Manfaat Modal Maya untuk Mengembangkan Entreprenurship Mahasiswa: Studi di Lingkungan Universitas Mataram
Authors: Bagis Abdul Azis , Surasni  , Santoso Budi 
Published: November 2022

Tujuan artikel ini adalah membuktikan bahwa pemanfaatan modal maya yang bersumber dari para mahasiswa itu sendiri, mampu mengembangkan kemampuan entrepreneurship secara lebih efektif. Pemanfaatan modal maya mampu mengoptimalkan keberadaan modal pisik, yang makin mahal dan sulit di era ekonomi bergejolak dewasa ini. Ketergantungan pada modal pisik, perlu dikurangi secara nyata dan diganti dengan kekuatan modal maya (virtual capital) yang lebih mampu menjamin keberlangsungan suatu bisnis (viability), di era yang bergejolak dewasa ini, yang bersumber dari para mahasiswa. Kemampuan entrepreneur para mahasiswa dikembangkan dengan bertumpu modal intelektual, modal sosial (net-working) dan modal kredibilitas para mahasiswa itu sendiri, sekaligus didukung oleh institusional dan para pihak terkait (stake holders). Efektivitas suatu modal maya terhadap pengembangan kemampuan entrepreneurship mahasiswa, sekaligus membutuhkan dukungan civitas akademika Universitas Mataram. Untuk itu pengkajian iklim akademika yang dialami oleh para mahasiswa, dipetakan di lingkungan Universitas Mataram. Pada akhirnya penelitian ini dapat menghasilkan suatu pola pembelajaran dan pemberdayaan entrepreneur mahasiswa Universitas Mataram, sekaligus dapat dimanfaatkan oleh perguruan tinggi lainnya di seluruh Indonesia.
Evaluasi Google Classroom Menggunakan Webqual 4.0 dalam Pembelajaran Online Selama Pandemi Covid-19
Authors: Putri Unzilla Savika , Putra Rocky Ardiansyah Yudistira , Mashuri Chamdan 
Published: November 2022

Abstrak – Pandemi covid-19 telah memberikan pengaruh di berbagai jenis kegiatan, terutama kegiatan pembelajaran. Pandemi mengubah sistem pembelajaran menjadi berbasis online atau daring. Pembelajaran daring merupakan upaya dimana proses pembelajaran tidak berlangsung namun dilakukan secara virtual melalui koneksi internet. Pembelajaran daring melalui media pembelajaran online merupakan peran yang penting untuk keberlangsungan pembelajaran selama covid-19 melanda. Aplikasi pembelajaran yang dipakai untuk untuk keberlangsungan pembelajaran adalah Google classroom. Website Google classroom merupakan sebuah e-learning milik perusahaan Google yang dapat dihubungkan dengan email, sehingga mudah untuk diakses. Tujuan dari penelitian adalah menghitung kualitas website Google classroom dalam perkuliahan pemrograman web pada Universitas Hasyim Asy’ari. Metode yang digunakan dalam pengukuran kualitas website Google classroom adalah WebQual 4.0. Penelitian ini dilakukan dengan memanfaatkan instrumen penelitian yang dibuat berdasarkan indikator WebQual 4.0 kemudian disebarkan kepada mahasiswa prodi Teknik Informatika semester 4. Hasil dari penelitian diperoleh jawaban responden bahwa tingkat kualitas website Google classroom berdasarkan ketiga indikator WebQual 4.0 dikategorikan baik meliputi Usability mendapatkan nilai 69%, Information Quality mendapatkan nilai 64%, dan Interaction Quality mendapatkan nilai 66%. Hasil nilai keseluruhan dari masing-masing indikator WebQual 4.0 yang didapatkan sebesar 66% dengan kategori baik.
Kata Kunci: Covid-19, Google classroom, Pemrograman web, WebQual 4.0.
Pengujian Flavonoid Total Dan Uji Aktivitas Antioksidan Fraksi Aktif Daun Akar Kaik-Kaik (Uncaria cordata (Lour.) Merr) Yang Berpotensi Sebagai Obat Diare
Authors: Silvia Silvia Deswita , Nadia Rahma Eva , Celloce Njurumana Violica , Yanuarti Rini 
Published: November 2022

kar kaik-kaik (Uncaria cordata (Lour.) Merr.) is a medicinal plant used forgenerations by the Dayak tribe to treat diarrhea and dysentery. This study aimsto determine the total flavonoid content and antioxidant activity of the activefraction of kaik-kaik root leaves which have the potential to cure diarrhea. Kaikkaik
root leaf extract was made by maceration using 70% ethanol. Totalflavonoid test was carried out using UV-VIS spectrophotometry with quercetinstandard. The results showed that the ethanol fraction had the highest flavonoidcontent, namely9.08 mg QE/g sample,n-hexane fraction of 5.21mg QE/gsample and ethyl acetate fraction of 3.54 mg QE/g. Testing of antioxidantactivity using the DPPH method. The results showed that the ethanol fractionhad a very strong antioxidant activity of 49.22 ppm, the n-hexane fraction had amoderate antioxidant activity of 108.22 ppm and the ethyl acetate fraction had amoderate antioxidant activity of 130.30. The total flavonoid content andantioxidant activity of the kaik-kaik root leaf extract indicate that the kaik-kaikroot leaf extract has the potential to be developed into herbal medicine to treatdiarrhea.
ANALISIS RISIKO USAHA AYAM PEDAGING DI KABUPATEN MOJOKERTO
Authors: Ramadhan Befrian Dio , Yektiningsih Endang , Sudiyarto Sudiyarto 
Published: November 2022

ABSTRAKAyam pedaging memiliki peran penting dalam sub sektor peternakan karena memiliki potensi yang besar dengan adanya peningkatan konsumsi daging ayam tiap tahunnya namun memiliki masalah yang komplek dari internal maupun eksternal sehingga menimbulkan risiko dan ketidakpastian. Penelitian ini bertujuan mengidentifikasi sumber penyebab risiko, menghitung besar risiko, dan menyusun strategi yang dapat diterapkan untuk mengendalikan sumber risiko yang paling menentukan dalam usaha ayam pedaging di Kabupaten Mojokerto.Populasi dalam penelitian ini adalah peternak ayam pedaging di Kabupaten Mojokerto. Metode penarikan sampel dilakukan dengan proportional random sampling dan jumlah sampel yang dianggap representatif dari populasi adalah 36 responden. Hasil analisis berdasarkan fish bone diagram teridentifikasi 17 sumber risiko dimana terbagi dalam enam risiko produksi, enam risiko pemasaran, dan lima risiko keuangan.Hasil analisis dengan failure mode and effect analysis terlihat hasil risk priority number tertinggi 576 keuntungan tergantung oleh targetan indeks performan, kemudian secara berturut-turut nilai risk priority number 567 serangan penyakit, 504 matinya ayam sehingga produktivitas menurun, 450 produk dijual dalam bentuk hidup, 441 adanya rasa takut jika meminjam pada perbankan. Peternak perlu untuk melakukan penguatan kelembagaan peternak melalui badan usaha milik desa berupa pengolahan ayam pedaging, dan lembaga keuangan mikro.Kata Kunci: analisis risiko usaha, sumber risiko, ayam pedaging.
PENYUSUNAN INDEKS KETAHANAN PANGAN KABUPATEN PROBOLINGGO
Authors: Zamrodah Yuhanin 
Published: November 2022

Penelitian ini dengan judul Penyusunan Indeks Ketahanan Pangan Kabupaten Probolinggo. Tujuan Penelitian ini antara lain agar tersedianya data bagi dinas/instansi terkait untuk mengatur kebijakan ketahanan pangan di wilayah, khususnya di wilayah yang sangat rentan pangan dan memberikan formulasi kebijakan dan program aksi penanggulangan rentan pangan untuk pemantauan standar pelayanan minimal untuk bidang pelayanan kerentanan pangan.Metode yang digunakan dalam penelitian ini adalah analisis deskriptif, yaitu analisis terhadap data yang bersifat kuantitatif dan kualitatif yang diolah untuk menggambarkan suatu kondisi penelitian tanpa bermaksud menguji hipotesis. Beberapa metode analisis yang akan diterapkan didalamnya yaitu Analisis SWOT, Analisis manajemen strategis untuk menyusun rencana pengusahaan dan rencana tindak.Hasil Penelitian menunjukkan bahwa Indeks Ketahanan Pangan Kabupaten Probolinggo tahun 2020 mencapai 71,19 yang menunjukkan sudah melebihi IKP Nasional tahun 2019 yaitu 54,8 dan juga lebih tinggi dari IKP Jawa Timur tahun 2019 yaitu 62,2. Indikator-indikator yang masih rendah (sangat rentan dan di Kabupaten Probolinggo adalah aspek akses pangan yaitu KK miskin. Hasil identifikasi dan pemetaan IKP tingkat Kecamatan Bantaran masuk kategori agak rentan. Hal ini disebabkan rasio luas baku sawah dan lahan yang agak rentan, penyedia sarana dan prasarana pangan yang masih kurang (rentan), rumah tangga miskin (sangat rentan).Kata kunci : Ketahanan Pangan, Kemiskinan, Kebijakan.
Analisis Trend dan Prediksi Produksi dan Konsumsi Komoditas Sayuran Sawi (Brassica Juncea L) di Indonesia Tahun 2020 s/d 2029
Authors: Hermansyah Dedi , Patiung Markus , Wisnujati Nugrahini Susantinah 
Published: November 2022

ABSTRAK Penelitian ini bertujuan untuk mengetahui trend estimasi produksi dan konsumsi sawi di Indonesia 10 tahun kedepan 2020 s/d 2029. Penelitian ini dilakukan di Indonesia dengan menggunakan data sekunder, dengan analisis menggunakan metode kuadrat terkecil (Least Square). Hasil penelitian ini menunjukan bahwa prediksi trend estimasi produksi komoditas sayuran sawi (Brassica juncea L) di Indonesia tahun 2020 s/d 2029 menunjukan pergerakan garis lurus dari kiri bawah ke kanan atas, bahwa untuk produksi sawi mengalami kecenderung meningkat, dengan rata-rata pertumbuhannya adalah 0,989 persen pertahun dimulai dari tahun 2020 sejumlah 649 ton, tahun2021 sejumlah 664,54 ton, tahun 2022 sejumlah 664,08 ton, tahun 2023 sejumlah 671,62 ton, tahun 2024 sejumlah 679, 16 ton, tahun 2025 sejumlah 686,7 ton, tahun 2026 sejumlah 694,24 ton, tahun 2027 sejumlah 701,78 ton, tahun 2028 sejumlah 709,32 ton, dan tahun 2029 sejumlah 716,86 ton. Prediksi trend estimasi konsumsi sayuran sawi (Brassica juncea L) di Indonesia tahun 2020 s/d 2029 menunjukan pergerakan garis lurus dari kiri bawah ke kanan atas, bahwa untuk konsumsi sawi mengalami kecenderungan meningkat, dengan rata-rata pertumbuhannya adalah 1,144 persen per tahun mulai dari tahun 2020 sejumlah 636,73 ton, tahun 2021 sejumlah 645,37 ton, tahun 2022 sejumlah 654,01 ton, tahun 2023 sejumlah 662,65 ton, tahun 2024 sejumlah 671,29 ton, tahun 2025 sejumlah 679,93 ton, tahun 2026 sejumlah 688,57 ton, tahun 2027 sejumlah 697,21 ton, tahun 2028 sejumlah 705,85 ton, dan tahun 2029 sejumlah 714,49 ton.Kata kunci: sawi, produksi, konsumsi, trend, estimasi.
Factors Influencing Male Participation in Maternal Health Care among Married Couples in Nepal: A Population-based Cross-sectional Study
Authors: Sharma S. , Aryal U. R. , Shrestha A. 
Published: November 2022

Background The male involvement in maternal health care is essential to reduce obstetric complications. However, there is little known about factors contributing to male participation in maternal health in Nepal.
Objective To assess predisposing, enabling and reinforcing factors contributing male participation in maternal health care in Nepal.
Method A population based cross-sectional study was conducted among 374 married couples. Ethical approval was obtained from Institutional Review Board of Kathmandu Medical College Teaching Hospital. The data was collected, using modified Safe Motherhood and Partnership Family Approach Model. Multivariable logistic regression was applied to account associated paternal factors. Concentration curve and concentration index were computed to measure equity gap between lowest and highest quintiles.
Result While four out of ten husbands reported high level of their involvement in maternal health care practices, wives reported relatively less involvement of their husbands. Logistic regression showed that husband having low family income, knows about immunization, contact with family planning providers were more likely to participate. In contrary, according to wives, husbands’ who have ever been to health facility, discuss family planning with others, contact with family planning providers and who knows about exclusive breast feeding were less likely to participate. The study also showed that socio-economic factors play a significant role.
Conclusion Male involvement in maternal health care practices is low. Predisposing, enabling and reinforcing factors play a significant role; however, some contradictions among husbands’ and wives’ perspectives provide strong evidence on significance of communication within partners on maternal health care issues.
Hormonal Contraceptives Use and Their Adverse Effects: A Cross-sectional Study among the Women Visiting Tertiary Care Center
Authors: Shakya Shrestha S. , Shrestha R. , Shrestha S. , Koju P. , Shrestha A. 
Published: November 2022

Background Hormonal contraceptives are one of the most commonly used means of contraception. Lack of contraception may lead to large family size, increased preexisting illness on pregnancy, social and economic instability, risk of unsafe abortion and so on. This may also lead to unintended pregnancies which may alter the outcomes of pregnancies as well. However, improper uses are associated with several serious adverse effects. Therefore, to achieve the optimum benefit with the least adverse effects, safe and effective use of these agents with monitoring of their pattern of use and patient compliance is very essential.
Objective To investigate the usage of hormonal contraceptives and the adverse effects associated with them.
Method A cross-sectional study was conducted in a family planning center of a tertiary care hospital. All women of reproductive age using hormonal contraceptives for at least 1 month were included in this study. Informed consent was taken from the patients and interviewed using a structured questionnaire. Statistical analysis was performed by using SPSS 20.
Result Among the 105 participants under this study, the mean (±SD) age was 29.08 (± 6.12) years. A majority (42, 40.0%) of them were using injectables. The average duration of use of hormonal contraceptives was 25.1 months ± 31.8 while a majority (60, 57.1%) were using contraceptives from < 3 months. Less chance of missed dose was the major reason (26.8%) for choosing injectable. Adverse effects were reported by 75.2% of the patients. The most common adverse effect was menstrual abnormalities (21.7%).
Conclusion Among various hormonal contraceptives, injectables were more commonly used. The majority of the participants responded to use injectables because of the least chance of missing the dose. The most common adverse effect reported was menstrual abnormalities.
Progesterone receptor expression and prediction of benefits of adjuvant radiotherapy in de novo atypical meningiomas after gross-total resection
Authors: Ren Leihao , Cheng Haixia , Chen Jiawei , Deng Jiaojiao , Wang Daijun , Xie Qing , Wakimoto Hiroaki , Hua Lingyang , Gong Ye 
Published: November 2022

OBJECTIVE
Benefits of adjuvant radiotherapy (ART) after gross-total resection (GTR) of de novo atypical meningiomas (AMs) are controversial, and factors predictive of radiotherapy benefits in patients with de novo AMs after GTR are unknown. The authors aimed to evaluate the benefits of ART and explore potential factors sensitizing AMs to ART.

METHODS
A total of 231 consecutive patients who were pathologically diagnosed with de novo AMs and treated with GTR (Simpson class I–III resections) from 2010 to 2018 were enrolled in the study. Clinicopathological and prognostic information was collected and analyzed. Univariate and multivariate Cox analyses were used to evaluate prognostic predictors and compare the response to radiotherapy. Propensity score matching (PSM) was used to balance the confounding bias in subgroups.

RESULTS
A total of 138 patients (59.74%) received ART. Progesterone receptor (PR) expression was positive in 157 patients (67.97%). During the mean follow-up period of 76.25 months, 65 patients (28.14%) experienced recurrence and 38 (16.45%) died of tumor progression. For disease-specific survival (DSS), ART was a better prognostic factor via univariate (p = 0.003) and multivariate (p = 0.025) analyses. For progression-free survival (PFS), univariate Cox analysis showed that ART improved PFS (p = 0.013), but multivariate analysis did not (p = 0.068). Positive PR expression (p = 0.019), age 53.5 years or younger (p = 0.012), and Ki-67 7.5% or lower (p = 0.025) were independent prognostic predictors for better PFS. In the subcohort analysis, the beneficial impact of ART was observed in the PR-negative cohort (p = 0.002) but not in the PR-positive cohort (p = 0.86). The heterogeneity analysis demonstrated that the PR-negative cohort was more sensitive to ART than the PR-positive cohort (p = 0.036). ART was not found to be associated with better PFS in younger patients (≤ 53.5 years, p = 0.14), older patients (> 53.5 years, p = 0.085), those with a Ki-67 index ≤ 7.5% (p = 0.068), or those with a Ki-67 > 7.5% (p = 0.13). The contrasting effects of ART in the PR-negative versus PR-positive cohorts remained true even after PSM, confirming that PR-negative, but not PR-positive, de novo AMs benefited from ART after GTR.

CONCLUSIONS
ART was an independent prognostic factor for DSS of patients with de novo AMs treated with GTR (p = 0.025), but not for PFS (p = 0.068). Negative PR expression was a radiosensitive biomarker on PFS for de novo AM patients after GTR.