bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Fu Yan Qing prescription on pelvic effusion, mass absorption and microenvironment of pelvic blood stasis in patients with sequelae of pelvic inflammatory disease of accumulation of dampness heat and blood stasis type
Authors: Zhang Sujuan , Yuan Lijin , Wang Yunliang , Sun Zhe 
Published: April 2022

Objective: To investigate the effect of Fu Yan Qing prescription on sequelae of pelvic inflammatory disease of accumulation of dampness heat and blood stasis type.
Methods: Total 80 patients with sequelae of sequelae of pelvic inflammatory disease of accumulation of dampness heat and blood stasis type were admitted to Baoding No.1 Central Hospital from December, 2018 to April, 2020 and divided into two groups according to the random number table, with 40 cases in each group. Patients in the control group were treated with conventional western medicine, while patients in the observation group were treated with Fu Yan Qing prescription orally. The clinical efficacy, the changes of traditional Chinese medicine (TCM) syndromes, local sign scores, visual analog scale (VAS) of pain, pelvic mass size, pelvic fluid volume and uterine blood flow parameters of the two groups before and after treatment were observed and compared, and the safety of the two groups was evaluated.
Results: The total efficacy after treatment in the observation group was 87.5%, which was significantly higher than that of 67.5% in the control group (p<0.05). The TCM syndrome scores, local signs scores, pain scores, size of pelvic mass and pelvic effusion in both groups decreased significantly after treatment (p<0.05), PSV indexes of the two groups were significantly increased after treatment (p<0.05), and these changes were even more pronounced in the observation group (p<0.05). Compared with before treatment, PI and RI indexes of the observation group were significantly decreased after treatment (p<0.05). The observation group experienced an adverse reaction in 7.5% cases considerably lower than the 27.5% of the control group (p<0.05).
Conclusion: Fu Yan Qing prescription is a safe and reliable treatment for patients with sequelae of pelvic inflammatory disease of accumulation of dampness heat and blood stasis type. It is worth promotion in clinical practice.
doi: https://doi.org/10.12669/pjms.38.5.4641
How to cite this:Zhang S, Yuan L, Wang Y, Sun Z. Effect of Fu Yan Qing prescription on pelvic effusion, mass absorption and microenvironment of pelvic blood stasis in patients with sequelae of pelvic inflammatory disease of accumulation of dampness heat and blood stasis type. Pak J Med Sci. 2022;38(5):---------. doi: https://doi.org/10.12669/pjms.38.5.4641
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Clinical value of propranolol combined with oxaliplatin and tigio in concurrent chemoradiotherapy for locally advanced gastric cancer
Authors: Chen Yong , Chen Yu , Wang Zhibang , Li He , Wang Yongqi 
Published: April 2022

Objectives: To investigate the clinical value of propranolol combined with oxaliplatin and tigio in concurrent chemoradiotherapy for locally advanced gastric cancer.
Methods: A total of 74 patients with locally advanced gastric cancer admitted to the First Affiliated Hospital of Hainan Medical University from August 2018 to June 2020 were selected as the subject and divided into two groups by random number table method: Group-A and Group-B, with 37 cases in each group. Patients in Group-A were treated with oxaliplatin injection and oral administration of tigio combined with concurrent radiotherapy, while patients in Group-B were given propranolol on the basis of treatment in Group-A. The clinical efficacy and incidence of adverse reactions in the two groups were observed.
Results: The response rate (RR) of Group-B was higher than that of Group-A, but with no statistically significant difference (P>0.05). No statistical difference was observed in the incidence of gastrointestinal reaction, bone marrow suppression, oral mucositis, and the incidence of grade III-IV adverse reactions in the two groups (P>0.05). There were no serious adverse reactions related to propranolol in Group-B, and the levels of tumor markers CEA, CA50, CA125, and CA242 in Group-B were lower than those in Group-A.
Conclusion: Propranolol combined with oxaliplatin and tigio boasts satisfactory sensitization safety in radiotherapy for gastric cancer, but its sensitization effect needs to be further investigated in a multi-center study involving large sample size.
doi: https://doi.org/-10.12669/pjms.38.5.5311
How to cite this:Chen Y, Chen Y, Wang Z, Li H, Wang Y. Clinical value of propranolol combined with oxaliplatin and tigio in concurrent chemoradiotherapy for locally advanced gastric cancer. Pak J Med Sci. 2022;38(5):---------. doi: https://doi.org/10.12669/pjms.38.5.5311
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Comparison between outcome of single dose of prophylactic antibiotic versus postoperative antibiotic in inguinal hernia surgery
Authors: Masood Ahmad , Arshad Abdur Rehman , Ashraf Mahnoor 
Published: April 2022

Objectives: To compare the outcome prophylactic antibiotics and routine pre-surgical and post-surgical in terms of incidence of surgical site infection (SSI) and to explore the effect of various factors such as duration of surgery and patient characteristics (if any).
Methods: A double-blinded prospective analysis of a total of 60 patients with the primary inguinal hernia was conducted from 24th August 2020 to 24th August 2021 at the Surgical Department of Nishtar Medical University & Hospital, Multan. The participants of the study were categorized into two groups such that 30 consecutive patients were placed in the study group who were administered with a single dose of prophylactic antibiotic 30 minutes before to mesh repair surgery and the remaining 30 patients were placed in the control group who were administered routine antibiotics pre and post-operatively. The effects in patients were observed till 30 days following surgery for any sign of infection. All the collected data were analyzed through SPSS (version 19).
Results: The rate of infection in both groups was noted. The incidence of infection in the study group (13.3%) was higher as compared to the control group (10%). No patient underwent mesh removal and no significant difference in terms of post-operative complications was observed in the results of both groups.
Conclusion: Both the treatments, prophylactic antibiotics and routine pre-surgical and post-surgical were equally effective. However, we recommend the administration of prophylactic since they are cost-effective and prevent bacterial drug resistance.
doi: https://doi.org/10.12669/pjms.38.5.5332
How to cite this:Masood A, Arshad AR, Ashraf M. Comparison between outcome of single dose of prophylactic antibiotic versus postoperative antibiotic in inguinal hernia surgery. Pak J Med Sci. 2022;38(5):---------. doi: https://doi.org/10.12669/pjms.38.5.5332
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Comparison of clinical effectiveness of conventional and self-etch sealant: a split mouth randomized controlled trial
Authors: Gupta Deveshi , Rao Arathi , Shenoy Ramya , Suprabha Baranya Srikrishna 
Published: April 2022

Background: Self-etching has been shown to be beneficial compared to the other resin sealants especially in pediatric practice. The present in-vivo study was designed to clinically evaluate the sealing ability and retention of the self-etching sealant compared to the conventional resin sealant. The aim was to evaluate and compare the retention and marginal integrity of the self-etch and acid etch sealant materials at three, six and twelve-month follow up. Methods: The study was designed as a double blinded, split mouth randomized controlled trial, . In total, 35 children (70 teeth) between 7 and 10 years of age formed part of the study. Group 1 received acid-etch sealant and Group 2 received self-etch sealants. The study participants and the investigator who performed the statistical analysis were blinded to the treatment allocation. All the samples were evaluated at 3, 6, and 12 months. The inter-group and intragroup comparison were carried out using the Chi-Square test and Friedman test with level of significance set at 5% and the P value less than 0.05. Results: Complete retention of sealants was observed in 34.5% of conventional acid etch (group 1) and 22.9% of self-etch samples (group 2) whereas complete loss of sealants were seen in 11.4% of group 1 and 20% of the group 2 samples and intergroup comparison of retention failure was non-significant (p=0.135). In total, 85.7% of the group 1 and 82.9% of the group 2 samples exhibited good marginal integrity with no clinical changes in the enamel around the margins but this was not statistically significant (p=0.5). Conclusions: Sealants with fewer procedural steps and those which provide adequate retention would be ideal for use in children. Thus, self-etch sealants have been found to be effective and efficient as a sealant in the present in-vivo study. Clinical Trials Registry, India registration: CTRI/2019/03/018343 (29/03/2019).
The signifying culture: An intercultural and qualitative analysis of Tiv and Yoruba folktales for moral instruction and character determination in children
Authors: Olugbemi-Gabriel Olumide , Ukpi Mbasughun 
Published: April 2022

Background: In the study of African communities, folktales have remained a constant element. With their origin in the culture of oral storytelling, folktales have often been used by older age groups to guide and mould behavioural patterns in children. In ancient and traditional African societies, children were gathered at the end of the day by older members of the community for tales by moonlight sessions aimed at guiding their moral decisions. With globalisation and its consequent effects such as migration, dislocation and disindigenisation, the culture of communal folktale sessions is experiencing a quick death. This paper engages with the relevance of folktales as moral guides for children in African societies and as a renewed path to increased societal stability facilitated by morally set individuals. Methods: The folktales were randomly selected from a pool of Tiv and Yoruba folktales in Nigeria. Two animal-based folktales which are part of shared folk culture were picked from the Tiv society and one from the Yoruba society. The study follows a narrative and content analysis approach where the selected folktales are corroborated by four key informants, two males and two females within the ages of 50-65. Results: With particular focus on the benefits of promoting and re-introducing the folktale culture to encourage positive behavioural traits amongst individuals in the society, the study primarily highlights folktales as reflective of human life. In identifying this similarity, the character of children is largely influenced by the moral values inherent in these folktales. Conclusions: There needs to be an increased use of media and audio-visual tools to expand the knowledge and accessibility of indigenous African folktales in order to preserve ethnic, national and social identity as well as to provide a moral compass for children.
Laboratory and experimental hut trial evaluation of VECTRON™ T500 for indoor residual spraying (IRS) against insecticide resistant malaria vectors in Burkina Faso
Authors: Bayili Koama , Ki Hyacinthe D. , Bayili Bazoma , Sow Bazoumana , Ouattara Abdoulaye , Small Graham , Dabire Roch K. , Diabate Abdoulaye 
Published: April 2022

Background: Malaria cases in some areas could be attributed to vector resistant to the insecticide. World Health Organization recommended insecticides for vector control are limited in number. It is essential to find rotational partners for existing Indoor Residual Spraying (IRS) products. VECTRON™ T500 is a novel insecticide with broflanilide as active ingredient. It has a mode of action on mosquitoes completely different to usually used. The aim of this study was to determine the optimum effective dose and efficacy of VECTRONTM against susceptible and resistant strains of Anopheles in Burkina Faso. Methods: VECTRON™ was sprayed at 50, 100 and 200 mg/m² doses onto mud and concrete blocks using Potter Spray Tower. The residual activity of broflanilide was assessed through cone bioassays 1 week and then monthly up to 14 months post spraying. Its efficacy was evaluated at 100 and 150 mg/m² against wild free-flying mosquitoes in experimental huts on both substrates. Actellic 300CS was applied at 1000 mg/m² as reference product. Cone assays were conducted monthly, using susceptible and resistant mosquito strains. Results: In the laboratory, VECTRON™ showed residual efficacy (≥80% mortality) on An. gambiae Kisumu up to 12 and 14 months, respectively, on concrete and mud blocks. Similar results were found with 100 and 200 mg/m² using An. coluzzii pyrethroid resistant strain. In experimental huts, a total of 19,552 An. gambiae s.l. were collected. Deterrence, blood-feeding inhibition and exophily with VECTRON™ treated huts were very low. At 100 and 150 mg/m², mortality of wild An. gambiae s.l. ranged between 55% and 73%. Monthly cone bioassay mortality remained >80% up to 9 months. Conclusions: VECTRON™ shows great potential as IRS formulation for malaria vector control. It can be added to the arsenal of IRS products for use in rotations to control malaria and manage mosquito insecticide resistance.
Difficulties in Teaching Children of Special Socio-Psychological Status
Authors: Vinogradova Natalya 
Published: April 2022

The article deals with the problems of organizing the activities of an educational organization to work with younger students who are included in
the “risk groups” according to their socio-psychological status. The features of the interaction of the teacher with students experiencing difficulties in the process of adaptation to the educational team, with features of physical and mental development, as well as with signs of deviant behavior are revealed. Particular attention is paid to the characteristics of the styles of successful interaction between the subjects of educational activity.
the case for philosophy for children in kenyan schools
Authors: Ominde Eliud Shani , K'odhiambo Atieno Kili , Gunga Samsom Okuro 
Published: April 2022

The significance of value-based education in character development and inculcation of ethical citizenship attitudes in Kenyan schools cannot be overemphasized. In the recent past, cases of unethical behaviour among primary school-going children and those who have graduated from this important segment of education have been on the rise, despite the various interventions by the Kenyan government to integrate value concerns in the curriculum. Since 2020, there has been a sharp increase in the cases of student-led arsons in learning institutions in Kenya. From independence, the government of Kenya adopted an indirect approach of value education that advocates for integration of values within regular curriculum. This strategy seems ineffective owing to an increase in the cases of indiscipline among learners. This study seeks to examine the application of Philosophy for Children (P4C) as the architecture for implementing value-based education and the realization of Chapter Six of the Constitution of Kenya because the values thatP4C aims to nurture are highly consistent with those of the Kenyan Constitution. Through P4C, the Kenyan Education system can achieve its goal of preparing responsible and ethical citizens of high moral integrity. Chapter Six of the Kenyan Constitution has laid the cornerstone principles of Leadership, Integrity and elements of ethical citizenship. It dictates the code of conduct for state officers and responsible citizenry. Through the Competency-Based Curriculum (CBC), the Ministry of Education seeks to inculcate these principles in the learners at an early age.
Promoção e proteção de direitos humanos e a necessária construção contra-hegemônica: possibilidades decoloniais
Authors: Cabral Maria Walkíria De Faro Coelho Guedes , Bacha e Silva Diogo 
Published: April 2022

Muito se discorre acerca dos instrumentos de promoção e proteção dos Direitos Humanos, a partir da descrição e análise dos sistemas formais criados no âmbito das Nações Unidas e das organizações regionais, bem como dos instrumentos internalizados decorrentes desses já mencionados. Ocorre que não são apenas esses sistemas legitimados as únicas formas de promoção e proteção de Direitos Humanos. Nesse sentido, o presente artigo visa discutir em que medida outras formas de promoção e proteção dos sujeitos de um Estado podem de fato contribuir para a construção de um sistema de Direitos Humanos mais complexo e efetivo. Apenas a partir dessa discussão, é possível marcar o espaço das construções contra-hegemônicas para a promoção e proteção dos Direitos Humanos, em especial de uma construção decolonial. Palavras-chave: Direitos Humanos; Teoria Crítica; Políticas Públicas; Contra-hegemonia; Decolonialidade. AbstractMuch is being addressed about the instruments for the promotion and protection of Human Rights, based on the description and analysis of the formal systems created within the framework of the United Nations and regional organizations, as well as the internalized instruments arising from these. It turns out that it is not only these legitimate systems the only ways of Human Rights promotion and protection. In this sense, this article aims to discuss which ways of promotion and protection of the subjects of a State can in fact contribute to the construction of a more complex and effective Human Rights system. Only from this discussion, it is possible to set a space of counter-hegemonic constructions for the promotion and protection of human rights, in particular a decolonial construction.Keywords: Human Rights, Critical Theory; Public Policies; Counter-hegemony; Decoloniality.
Aborto e influências religiosas no ordenamento jurídico brasileiro: o retrocesso legislativo frente às práticas abortivas
Authors: Mantovani Lucas Dos Santos , Cazelatto Caio Eduardo Costa , Cardin Valéria Silva Galdino 
Published: April 2022

ResumoO trabalho traz à discussão, por meio da revisão sistemática da literatura, as pesquisas, estudos, tramitações de projetos de lei e decisões judiciais relacionadas à temática do aborto e suas intersecções com as influências religiosas no ordenamento jurídico brasileiro, sobretudo perante a atividade legislativa e os consequentes efeitos sociais e políticas no âmbito da política nacional e sobre o papel do Estado. Para isso, foi investigado o aborto sob a perspectiva do direito à vida, apresentando-se as teorias que sustentam o direito à vida, bem como as previsões constitucionais referentes à dignidade da pessoa e da vida humana, como o direito à autonomia da mulher e do acesso à justiça social. Ainda, foram exploradas as influências e os reflexos das interferências religiosas perante a elaboração de leis e na atuação do Poder Judiciário. A discussão revela que o debate da questão do aborto sob a perspectiva do direito à vida e sua relação com os Direitos da Personalidade são relevantes para o pensamento crítico a respeito da importância de uma reformulação nas leis restritivas às práticas abortivas atualmente vigentes.Palavras-Chave: Direito à Autodeterminação das Mulheres; Direitos à Saúde; Influências religiosas; Práticas abortivas; Retrocesso legislativo. AbstractThis work brings to the discussion, through a systematic literature review, the researches, studies, processing of bills and court decisions related to the theme of abortion and its intersections with religious influences in the Brazilian legal system, especially regarding the legislative activity and the consequent social and political effects in the scope of national politics and on the role of the State. For this, abortion was investigated from the perspective of the right to life, presenting the theories that support the right to life, as well as the constitutional provisions regarding the dignity of the person and human life, such as the right to autonomy of women and access to social justice. Still, the influences and reflexes of religious interferences in the elaboration of laws and in the performance of the Judiciary were explored. The discussion reveals that the debate on the issue of abortion from the perspective of the right to life and its relationship with Personality Rights are relevant to critical thinking about the importance of reformulating the laws restricting abortion practices currently in force.Keywords: Women's Right to Self-Determination; Rights to Health; Religious influences; Abortive practices; Legislative setback.