bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ovarian imaging radiomics quality score assessment: an EuSoMII radiomics auditing group initiative
Authors: Ponsiglione Andrea , Stanzione Arnaldo , Spadarella Gaia , Baran Agah , Cappellini Luca Alessandro , Lipman Kevin Groot , Van Ooijen Peter , Cuocolo Renato 
Published: October 2022

Abstract
Objective
To evaluate the methodological rigor of radiomics-based studies using noninvasive imaging in ovarian setting.

Methods
Multiple medical literature archives (PubMed, Web of Science, and Scopus) were searched to retrieve original studies focused on computed tomography (CT), magnetic resonance imaging (MRI), ultrasound (US), or positron emission tomography (PET) radiomics for ovarian disorders’ assessment. Two researchers in consensus evaluated each investigation using the radiomics quality score (RQS). Subgroup analyses were performed to assess whether the total RQS varied according to first author category, study aim and topic, imaging modality, and journal quartile.

Results
From a total of 531 items, 63 investigations were finally included in the analysis. The studies were greatly focused (94%) on the field of oncology, with CT representing the most used imaging technique (41%). Overall, the papers achieved a median total RQS 6 (IQR, −0.5 to 11), corresponding to a percentage of 16.7% of the maximum score (IQR, 0–30.6%). The scoring was low especially due to the lack of prospective design and formal validation of the results. At subgroup analysis, the 4 studies not focused on oncological topic showed significantly lower quality scores than the others.

Conclusions
The overall methodological rigor of radiomics studies in the ovarian field is still not ideal, limiting the reproducibility of results and potential translation to clinical setting. More efforts towards a standardized methodology in the workflow are needed to allow radiomics to become a viable tool for clinical decision-making.

Key Points
• The 63 included studies using noninvasive imaging for ovarian applications were mostly focused on oncologic topic (94%).
• The included investigations achieved a median total RQS 6 (IQR, −0.5 to 11), indicating poor methodological rigor.
• The RQS was low especially due to the lack of prospective design and formal validation of the results.
Delir bei Demenz
Authors: De Biasi Johanna , Reininghaus Eva , Schoberer Daniela 
Published: October 2022

Zusammenfassung
Hintergrund
Ein die Demenz überlagerndes Delir („delirium superimposed on dementia“, DSD) ist ein weit verbreitetes, aber häufig unerkanntes Problem. Ein solches Delir mindert die Lebensqualität von Patient/-innen mit einer Demenzerkrankung erheblich. Das Bewusstsein für dieses Zustandsbild muss bei Gesundheitsfachpersonen geschärft werden, um dessen Entwicklung frühzeitig erkennen und von Demenz ohne Delir unterscheiden zu können und dementsprechend zu behandeln.

Ziel des Beitrages
Dieser Review beschreibt den bisherigen Stand der erforschten diagnostischen, präventiven und therapeutischen Methoden im Umgang mit DSD.

Material und Methoden
Eine umfassende Literaturrecherche mit den Begriffen „Demenz“, „Delir“, „Delirium superimposed on dementia“ und „DSD“ wurde in der Datenbank PubMed durchgeführt, ebenso wie Literaturrecherchen über Google-Scholar.

Ergebnisse
Die diagnostischen Möglichkeiten zur Detektion von DSD sind zurzeit auf Instrumente zur alleinigen Delirdiagnostik beschränkt, wie etwa die Confusion Assessment Method. Ein regelmäßiges multiprofessionelles Screening der Risikopatient/-innen ist zur frühen Detektion und Prävention dieser Erkrankung essenziell. Auch die Behandlung erfordert einen interdisziplinären Zugang. Eine pharmakologische Therapie ist indiziert, wenn nichtpharmakologische Maßnahmen nicht ausreichen oder zur Behandlung von delirauslösenden Ursachen. Im Vordergrund stehen die psychische und physische Betreuung der Patient/-innen und die Beseitigung von Risikofaktoren für die Entwicklung eines DSD.

Diskussion
DSD ist ein ernst zu nehmendes Syndrom. Noch gibt es keinen Goldstandard in der Diagnostik und Therapie. Multikomponente nichtpharmakologische Interventionsprogramme reduzieren nachweislich die Inzidenz eines Delirs. Deren Nutzen bei DSD muss in großen multizentrischen Studien überprüft werden.
Study of the dynamic performance boundaries of a converter’s energy storage device
Authors: Zhang Ziqian , Lehmal Carina , Hackl Philipp , Schuerhuber Robert , Zuo Jianyong 
Published: October 2022

AbstractMaintaining frequency stability is one of the central objectives of power grid operation. While this task is currently primarily done by employing stored rotational energy, in a converter-dominated grid fed by renewables, sources, such as wind and photovoltaic, must be involved in the frequency control of the power grid in order to maintain a stable, efficient grid operation in the process of achieving carbon neutrality. However, due to the lack of rotational inertia reserves, the converter requires additional energy storage devices to respond to the grid’s frequency regulation requirements. For modeling a converter-dominated grid, the behavior of such additional short-time storage must be modeled properly in order to obtain realistic simulation results, which allow drawing conclusions about the frequency stability behavior of the grid. This paper investigates the boundaries of the dynamic performance of the output current of the energy storage device so that the converter can achieve the function of frequency regulation in a more economical manner. In this paper, a dynamic supporting converter based on a phase-locked loop and a grid-forming converter, as well as the DC link of the converter containing an energy storage system, are modeled. On this basis, the optimal boundaries of the dynamic performance of the output current of the energy storage device are investigated. It is concluded that not only the proper sizing of grid-supporting energy storage devices is important for proper grid operation, but the dynamic behavior also has to be modeled and designed properly in order to guarantee a stable operation under all circumstances.
Representing the Structure of a Debate
Authors: Harrell Maralee 
Published: October 2022

AbstractIn this article I aim to use the 1948 Russell-Copleston debate to highlight some recent problems I have experienced teaching argument analysis in my philosophy courses. First, I will use argument diagramming to represent the arguments in the debate while reflecting on the use of this approach use to teach argument analysis skills. Then, I will discuss the tools and methods scholars have proposed to represent debates, rather than just individual arguments. Finally, I will argue that there is not, but needs to be, a good way to represent argumentative debates in a way that neither obscures the essential details of the exchange nor becomes too unwieldy to extract a sense of the overall debate.
Validation of physics-based ground shaking scenarios for empirical fragility studies: the case of the 2009 L’Aquila earthquake
Authors: Rosti A. , Smerzini C. , Paolucci R. , Penna A. , Rota M. 
Published: October 2022

AbstractThis paper explores and validates the use of ground shaking scenarios generated via 3D physics-based numerical simulations (PBS) for seismic fragility studies. The 2009 L’Aquila seismic event is selected as case-study application, given the availability of a comprehensive post-earthquake database, gathering observed seismic damages detected on several building typologies representative of the Italian built environment, and of a validated numerical model for the PBS of ground shaking scenarios. Empirical fragility curves are derived as a function of different seismic intensity measures, by taking advantage of an improved statistical technique, overcoming possible uncertainties in the resulting estimates entailed by data aggregation. PBS-based fragility functions are compared to the corresponding sets of curves relying on updated ShakeMaps. The predictive capability of the adopted simulation strategies is then verified in terms of seismic damage scenarios, by respectively coupling PBS- and ShakeMap-based fragility models with the corresponding ground shaking scenarios. Comparison of observed and predicted damage distributions highlights the suitability of PBS for region-specific seismic vulnerability and risk applications.
Growth Enhancement of Radish Seed Induced by Low-Temperature Argon Plasma
Authors: Guragain Rajesh Prakash , Baniya Hom Bahadur , Pradhan Suman Prakash , Pandey Bishnu Prasad , Shrestha Bikash , Fronczak Maciej , Kierzkowska-Pawlak Hanna , Subedi Deepak Prasad 
Published: October 2022

AbstractThe process of seed germination is described as the culmination of a series of events that start with wetting and end with the emergence of the embryo (typically the radicle) from the seed coat. This method has an impact on crop output and quality. The characteristics of the seed surface and the surroundings have an impact on the kinetics and volume of water absorption by seeds. As a result, modifying the characteristics of a seed's surface is a useful tactic for influencing seed germination. Low-temperature plasma (LTP) treatment of the seed for surface activation is now being researched as an effective pre-sowing technique. This study looked at the effects of LTP on radish (Raphanus sativus) seeds at room temperature for various times. The seed's germination properties, growth parameters, water contact angle (WCA), Scanning Electron Micrograph (SEM), and FTIR analysis were examined. WCA and SEM examination revealed a considerable alteration in the seed coat following LTP treatment, which is directly connected to water permeability into the seeds. Similarly, FTIR analysis confirmed that the enhancement of the hydrophilic properties of the seeds following plasma treatment is likely due to the damage of the hydrophobic moieties on the seeds' surface. The LTP treatment improved each germination-related parameter, including the vigor index, chlorophyll content, in-vitro radical scavenging activities, total flavonoid, and phenol in the seedlings. Our findings indicate that LTP treatment has a beneficial impact on early seed sprouting and the development of radish.
Teaching sourcing during online inquiry – adolescents with the weakest skills benefited the most
Authors: Hämäläinen Elina K. , Kiili Carita , Räikkönen Eija , Lakkala Minna , Ilomäki Liisa , Toom Auli , Marttunen Miika 
Published: October 2022

AbstractSourcing - identifying, evaluating, and using information about the sources of information - assists readers in determining what to trust when seeking information on the Internet. To survive in the post-truth era, students should be equipped with sufficient sourcing skills. This study investigated the efficacy of a teacher-led intervention aimed at fostering upper secondary school students’ (N = 365) sourcing during online inquiry. The intervention (4 × 75 min) was structured in accordance with the phases of online inquiry: locating, evaluating, synthesizing, and communicating information. During the intervention, teachers demonstrated why and how to source, and students practiced sourcing by investigating a controversial topic on the Internet. Students worked in small groups and their work was supported with analysis and reflection prompts. Students’ sourcing skills were measured with a web-based online inquiry task before and after the intervention. Compared to controls, the intervention fostered students’ abilities in three of the four skills measured (sourcing in search queries, credibility judgments, and written product). Depending on the sourcing skill, 4–25% of students showed improved performance. The students with low sourcing skills to begin with, benefited the most from the intervention. The study demonstrated that students’ sourcing skills can be supported throughout online inquiry.
The effect of surgical weight loss on upper airway fat in obstructive sleep apnoea
Authors: Sutherland Kate , Smith Garett , Lowth Aimee B. , Sarkissian Nina , Liebman Steven , Grieve Stuart M. , Cistulli Peter A. 
Published: October 2022

Abstract
Purpose
Obesity is a reversible risk factor for obstructive sleep apnoea (OSA). Weight loss can potentially improve OSA by reducing fat around and within tissues surrounding the upper airway, but imaging studies are limited. Our aim was to study the effects of large amounts of weight loss on the upper airway and volume and fat content of multiple surrounding soft tissues.

Methods
Participants undergoing bariatric surgery were recruited. Magnetic resonance imaging (MRI) was performed at baseline and six-months after surgery. Volumetric analysis of the airway space, tongue, pharyngeal lateral walls, and soft palate were performed as well as calculation of intra-tissue fat content from Dixon imaging sequences.

Results
Among 18 participants (89% women), the group experienced 27.4 ± 4.7% reduction in body weight. Velopharyngeal airway volume increased (large effect; Cohen’s d [95% CI], 0.8 [0.1, 1.4]) and tongue (large effect; Cohen’s d [95% CI], − 1.4 [− 2.1, − 0.7]) and pharyngeal lateral wall (Cohen’s d [95% CI], − 0.7 [− 1.2, − 0.1]) volumes decreased. Intra-tissue fat decreased following weight loss in the tongue, tongue base, lateral walls, and soft palate. There was a greater effect of weight loss on intra-tissue fat than parapharyngeal fat pad volume (medium effect; Cohen’s d [95% CI], − 0.5 [− 1.2, 0.1], p = 0.083).

Conclusion
The study showed an increase in velopharyngeal volume, reduction in tongue volume, and reduced intra-tissue fat in multiple upper airway soft tissues following weight loss in OSA. Further studies are needed to assess the effect of these anatomical changes on upper airway function and its relationship to OSA improvement.
Nearness to God: Danish Muslims and Taqwa-infused faith frames
Authors: Lyngsøe Maria Lindebæk , Stjernholm Simon 
Published: October 2022

AbstractThis article advocates for an increased attention to how piously striving Muslims learn about, cultivate, and experience nearness to God. The empirical material is taken from our current research on Danish Muslims’ engagement with Islamic teaching and learning. We examine examples of oral teachings that instruct the audience to be constantly aware of God and address him directly in prayer, examples of how an awareness of God is cultivated and practiced in everyday life, and individual narratives of experiences of being close to or helped by God. With inspiration from the anthropology of Christianity as well as Islam, we propose an analytical model for understanding the process whereby Muslim efforts to draw near to God can ‘work’. Three interrelated dynamics are crucial to this process, and we identify each through our reading of existing scholarship. The dynamics at play are, respectively, a taqwa-infused faith frame, its related semiotic ideology, and a relationship of experienced reciprocal agency with God.
The elephant in the room is really a cow: using consumption corridors to define sustainable meat consumption in the European Union
Authors: Cué Rio Miriam , Bovenkerk Bernice , Castella Jean-Christophe , Fischer Daniel , Fuchs Richard , Kanerva Minna , Rounsevell Mark D. A. , Salliou Nicolas , Verger Eric O. , Röös Elin 
Published: October 2022

AbstractImplementing the European Green Deal requires a consistent food systems’ policy that involves not only targeting the supply side but also conducting extensive changes in diets at the consumer level. Reducing meat consumption is an obvious strategy to put the European food system on track to meet the Green Deal’s goals. This cannot be achieved by focusing solely on consumer choice and individual responsibility. Stronger governance is required to reduce the scale of meat consumption to sustainable levels. Such governance needs to be informed by a holistic definition of “sustainable meat consumption”, designed to ensure that important sustainability priorities are not neglected, and to account for all emissions associated with EU consumption, regardless of where production takes place. This article presents a conceptual framework to define “sustainable meat consumption” based on the concept of consumption corridors (CCs). A CC is the space between a minimum (the floor) and maximum (the ceiling) consumption level, which allows everybody to satisfy their needs without compromising others’ ability to meet their own. Embedded in a powerful set of principles (recognizing universal needs; tackling both over and under-consumption; framing food as a common good; promoting public participation; and addressing environmental justice and planetary sustainability), CCs are attuned to the Green Deal’s ambition to “leave no one behind”, in the EU and beyond. CCs provide a demand-side solution encompassing a more equitable alternative to discuss what is actually a “fair share” of the world’s limited resources when it comes to meat consumption.
Quantification of breast lymphoedema following conservative breast cancer treatment: a systematic review
Authors: Fearn Nicola , Llanos Catalina , Dylke Elizabeth , Stuart Kirsty , Kilbreath Sharon 
Published: October 2022

Abstract
Purpose
Breast lymphoedema is a possible side effect of breast conserving surgery, but it is poorly understood. This is due, in part, to difficulty assessing the breast. This systematic review described outcome measures that quantify breast lymphoedema signs and symptoms and evaluated the measurement properties for these outcome measures.

Method
Seven databases were searched using terms in four categories: breast cancer, lymphoedema and oedema, clinician reported (ClinROM) and patient reported outcome measures (PROM) and psychometric and measurement properties. Two reviewers independently reviewed studies and completed quality assessments. The Consensus-based Standards for the Selection of Health Measurement Instruments (COSMIN) methodology was used for studies including measurement property evidence.

Results
Fifty-six papers were included with thirteen questionnaires, eight patient-reported rating scales, seven physical measures, seven clinician-rating scales and four imaging techniques used to quantify breast lymphoedema. Based on COSMIN methodology, one ClinROM had sufficient reliability, ultrasound measuring dermal thickness. Tissue dielectric constant (TDC) measuring local tissue water had promising reliability. Four questionnaires had sufficient content validity (BLYSS, BLSQ, BrEQ and LYMQOL-Breast).

Conclusions
Ultrasound is recommended to reliably assess breast lymphoedema signs. No PROM can be recommended with confidence, but BLYSS, BLSQ, BrEQ and LYMQOL-Breast are promising. Further research is recommended to improve evidence of measurement properties for outcome measures.

Implications for Cancer Survivors
There are many approaches to assess breast lymphoedema, but currently, only ultrasound can be recommended for use, with others, such as TDC and questionnaires, showing promise. Further research is required for all approaches to improve evidence of measurement properties.
The effect of changing pregnancy intentions on preconception health behaviors: a prospective cohort study
Authors: Din Hena Naz , Strong David , Singh-Carlson Savitri , Corliss Heather L. , Hartman Sheri J. , Madanat Hala , Su H. Irene 
Published: October 2022

Abstract
Purpose
Pregnancy intentions are associated with preconception health behaviors but are understudied among female adolescent and young adult (AYA) cancer survivors. Preconception health is critical for survivors because they face unique risks to fertility and pregnancy from late effects of cancer treatments. This study prospectively assessed the effect of pregnancy intention on physical activity (PA) and smoking behaviors among female AYA survivors.

Methods
A cohort of 1049 female AYA survivors were recruited between 2013 and 2017. Participants were 18–39 years and had completed primary cancer treatment. Longitudinal mixed effects analysis was conducted on participants who completed at least 2 of 4 questionnaires over 1.5 years. Two measures were used to capture multiple dimensions of pregnancy intention. The pregnancy intention score (PIS) captured wanting and planning dimensions and represented a scaled response of low to high intention. The trying dimension captured urgent intention and ranged from not trying, ambivalent (neither attempting nor avoiding pregnancy), and trying now. Intention change was assessed between each consecutive time points. Final analysis was conducted with multiple imputations.

Results
Survivors with increased intention measured by trying was associated with increased PA over time (adjusted B [95%CI]: 0.3 [0.01, 0.5]) compared to survivors with no changes or decreased trying intention. PIS was not significantly associated with preconception behaviors. No measure of intention was associated with smoking behavior.

Conclusions
Increasingly urgent pregnancy intention (trying dimension) was associated with higher preconception PA.

Implications for cancer survivors
Screening for immediate intentions can identify AYA survivors in need of early preconception health promotion.
Six Decades of History of Hypertension Research at the University of Toledo: Highlighting Pioneering Contributions in Biochemistry, Genetics, and Host-Microbiota Interactions
Authors: Gokula Veda , Terrero David , Joe Bina 
Published: October 2022

Abstract
Purpose of Review
The study aims to capture the history and lineage of hypertension researchers from the University of Toledo in Ohio and showcase their collective scientific contributions dating from their initial discoveries of the physiology of adrenal and renal systems and genetics regulating blood pressure (BP) to its more contemporary contributions including microbiota and metabolomic links to BP regulation.

Recent Findings
The University of Toledo College of Medicine and Life Sciences (UTCOMLS), previously known as the Medical College of Ohio, has contributed significantly to our understanding of the etiology of hypertension. Two of the scientists, Patrick Mulrow and John Rapp from UTCOMLS, have been recognized with the highest honor, the Excellence in Hypertension award from the American Heart Association for their pioneering work on the physiology and genetics of hypertension, respectively. More recently, Bina Joe has continued their legacy in the basic sciences by uncovering previously unknown novel links between microbiota and metabolites to the etiology of hypertension, work that has been recognized by the American Heart Association with multiple awards. On the clinical research front, Christopher Cooper and colleagues lead the CORAL trials and contributed importantly to the investigations on renal artery stenosis treatment paradigms. Hypertension research at this institution has not only provided these pioneering insights, but also grown careers of scientists as leaders in academia as University Presidents and Deans of Medical Schools. Through the last decade, the university has expanded its commitment to Hypertension research as evident through the development of the Center for Hypertension and Precision Medicine led by Bina Joe as its founding Director.

Summary
Hypertension being the top risk factor for cardiovascular diseases, which is the leading cause of human mortality, is an important area of research in multiple international universities. The UTCOMLS is one such university which, for the last 6 decades, has made significant contributions to our current understanding of hypertension. This review is a synthesis of this rich history. Additionally, it also serves as a collection of audio archives by more recent faculty who are also prominent leaders in the field of hypertension research, including John Rapp, Bina Joe, and Christopher Cooper, which are cataloged at Interviews.