bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emerging technologies and the use case: A multi‐year study of drone adoption
Authors: Maghazei Omid , Lewis Michael A. , Netland Torbjørn H. 
Published: June 2022

AbstractAlthough disruptive “Industry 4.0” technologies often lack a clear business case, vendors are advocating and companies are actively exploring their use in operations settings. The technology management literature suggests that successful adoption derives from an appropriate fit between the specific technology and (1) economic and strategic factors, (2) operational and supply chain factors, and (3) organizational and behavioral factors. Through a five‐year research project, we explore how drones—an archetypal emerging technology supported by a thriving vendor ecosystem—transitioned from early ideas to experimental applications to full adoption in daily operations. We analyze a range of data, including exploratory interviews with drone ecosystem actors, a secondary dataset, and case studies of drone applications in Geberit and IKEA. Key findings relate to our observation that technology adoption patterns for emerging technologies do not always follow the traditional linear logic of technology fit. We find that emerging technologies are characterized by a dynamic interaction between technology push from a thriving ecosystem and market pull from companies exploring meaningful operational and business value using the concept of “use case.” Based on these findings, we contribute to the technology management literature with an alternative technology adoption framework for emerging “Industry 4.0” technologies.
Action mechanisms of two key xanthine oxidase inhibitors in tea polyphenols and their combined effect with allopurinol
Authors: Zhang Guowen , Zhu Miao , Liao Yijing , Gong Deming , Hu Xing 
Published: June 2022

AbstractBACKGROUNDTea polyphenols have been reported to have the effect of lowering uric acid. However, there are few studies on the inhibitory effects and molecular mechanisms of specific catechins on the urate‐metabolizing enzyme xanthine oxidase (XO). In this research, multiple spectroscopic methods and computer simulations were used to determine the inhibitory ability and mechanisms of epigallocatechin gallate (EGCG) and gallocatechin gallate (GCG) on XO.RESULTSHerein, EGCG and GCG reversibly inhibited XO activity in a mixed manner, with IC50 values of 40.50 ± 0.32 and 33.60 ± 0.53 μmol L−1, and also decreased the superoxide anion radical (O2−) of the catalytic system by reducing the XO molecule and inhibiting the formation of uric acid. The combination of EGCG or GCG with allopurinol showed synergistic inhibition on XO. The binding of EGCG or GCG to XO with moderate affinity formed a stable complex by hydrogen bonds and van der Waals forces. The presence of EGCG and GCG made the structure of XO more stable and compact. The two inhibitors bound to the vicinity of flavin adenine dinucleotide (FAD) in XO, hindering the entry of substrate; thus the activity of XO was suppressed.CONCLUSIONBoth EGCG and GCG are excellent natural XO inhibitors, and inhibited the activity of XO by occupying the channel of the substrate to enter the active center and interfering with the dual substrate reaction catalyzed by XO. These findings provide a scientific basis for the application of catechins in dietary supplements and medicines with lowering uric acid effects. © 2022 Society of Chemical Industry.
Pre‐gelatinization and cellulase addition improve fermentation performance and antioxidant activity of black rice wine
Authors: Yang Liu , Chen Xin , Zhou Yue , Mei Lu , Wu Yuting , Sun Hanju , Yao Shengfei , Xu Shangying , Li Jinglei 
Published: June 2022

AbstractBACKGROUNDBlack rice contains a variety of bioactive substances that contribute to the high nutritional value of black rice wine (BRW). However, the dense bran layer of black rice retards the fermentation rate and reduces the dissolution of active components. Hence, this study aims to investigate the effects of pre‐gelatinization (PG) before cooking and cellulase (CE) addition during fermentation on the fermentation performance of BRW and its antioxidant activity.RESULTSPG combined with CE treatments (PGCE) increases the alcohol content, free amino acid content, volatile flavor content and total antioxidant activity of BRW by 90.81%, 15.36%, 38.05% and 19.56%, respectively, compared with the control group. Scanning electron microscopy, low‐field nuclear magnetic resonance and texture properties analysis indicate that PG treatment increases gelatinization degree of starch during cooking, decreases bound water content in cooked black rice and promotes unbound water release. CE destroys the aleurone layer structure, facilitates the release of unbound water and the exposure of rice starch, thus increasing the reaction area and extravasation content significantly, which is beneficial to microbial growth and fermentation. Incomplete aleurone layer also promotes the dissolution of anthocyanins, phenols and other active substances, increasing the antioxidant activities of BRW.CONCLUSIONPG and CE treatments reduce the fermentation time and improve the quality of BRW by destroying the black rice structure. © 2022 Society of Chemical Industry.
Multicenter study of racial and ethnic inequities in liver transplantation evaluation: Understanding mechanisms and identifying solutions
Authors: Strauss Alexandra T. , Sidoti Carolyn N. , Purnell Tanjala S. , Sung Hannah C. , Jackson John W. , Levin Scott , Jain Vedant S. , Malinsky Daniel , Segev Dorry L. , Hamilton James P. , Garonzik‐Wang Jacqueline , Gray Stephen H. , Levan Macey L. , Scalea Joseph R. , Cameron Andrew M. , Gurakar Ahmet , Gurses Ayse P. 
Published: June 2022

Abstract
Racial and ethnic disparities persist in access to the liver transplantation (LT) waiting list; however, there is limited knowledge about underlying system‐level factors that may be responsible for these disparities. Given the complex nature of LT candidate evaluation, a human factors and systems engineering approach may provide insights. We recruited participants from the LT teams (coordinators, advanced practice providers, physicians, social workers, dieticians, pharmacists, leadership) at two major LT centers. From December 2020 to July 2021, we performed ethnographic observations (participant–patient appointments, committee meetings) and semistructured interviews (N = 54 interviews, 49 observation hours). Based on findings from this multicenter, multimethod qualitative study combined with the Systems Engineering Initiative for Patient Safety 2.0 (a human factors and systems engineering model for health care), we created a conceptual framework describing how transplant work system characteristics and other external factors may improve equity in the LT evaluation process. Participant perceptions about listing disparities described external factors (e.g., structural racism, ambiguous national guidelines, national quality metrics) that permeate the LT evaluation process. Mechanisms identified included minimal transplant team diversity, implicit bias, and interpersonal racism. A lack of resources was a common theme, such as social workers, transportation assistance, non–English‐language materials, and time (e.g., more time for education for patients with health literacy concerns). Because of the minimal data collection or center feedback about disparities, participants felt uncomfortable with and unadaptable to unwanted outcomes, which perpetuate disparities. We proposed transplant center–level solutions (i.e., including but not limited to training of staff on health equity) to modifiable barriers in the clinical work system that could help patient navigation, reduce disparities, and improve access to care. Our findings call for an urgent need for transplant centers, national societies, and policy makers to focus efforts on improving equity (tailored, patient‐centered resources) using the science of human factors and systems engineering.
Preparing Well‐Defined Polyacrylamide‐b‐polycarbonate by Integrating Photoiniferter Polymerization and TBD‐Catalyzed ROP
Authors: Sun Wei , Shen Xiang , Liu Jingrui , Wu Zhaoqiang , Chen Hong 
Published: June 2022

AbstractThe dual‐initiator technique allows the polymerization of different monomers from orthogonal polymerization mechanisms to obtain block copolymers (BCPs). In this study, it is attempted to combine photoiniferter living free radical polymerization and organocatalytic ring‐opening polymerization (ROP) to design a hydroxyl‐functionalized carbamodithioate, i.e., 4‐(hydroxymethyl)benzyl diethylcarbamodithioate (HBDC), which can integrate photoiniferter polymerization of acrylamide monomers and ROP of cyclic carbonates. As a proof of concept, the monomer applicability is further extended to acrylates and lactones. The results confirm that the two polymerization systems are experimentally compatible in a stepwise sequence as well as in a simultaneous one‐pot process to synthesize BCPs. It is reasonable to assume that HBDC can allow for simple and efficient one‐pot access to well‐defined BCPs from a larger range of monomers, which is more advantageous from the operational, economical, and environmental points of view.
Special Section Overview: Effects of Ecosystem Change on North American Percid Populations
Authors: Boehm Hadley I. A. , Isermann Daniel A. , Ermer Mark J. , Eslinger Lawrence D. , Hansen Gretchen J. A. , Logsdon Dale E. 
Published: June 2022

Abstract
Walleye Sander vitreus, Sauger S. canadensis, and Yellow Perch Perca flavescens (referred to as percids herein) are collectively among the most culturally and ecologically important fish species in North America. As ecosystems change in response to environmental drivers, such as climate change, nutrient loading, and invasive species, there is a need to understand how percid populations respond to these changes. To address this need, a symposium was held during the 81st Annual Midwest Fish and Wildlife Conference to bring fishery scientists and managers together to describe and discuss percid population responses to ecosystem change. Prevailing symposium themes included the challenge of identifying mechanisms responsible for population-level changes, developing strategies to adaptively manage for resilient fisheries, and consideration of scale, context, and methods when interpreting variable results. Given the uncertainty of how ecosystem changes affect percid populations, participants emphasized the importance of communicating uncertainties to stakeholders, implementing data-driven management strategies, setting realistic goals, and revising management actions in an adaptive framework. There was universal agreement on both the challenge and necessity of facilitating constructive engagement among stakeholders in cooperative decision making. Symposium participants identified knowledge gaps and discussed future efforts to build on our current understanding of percid populations, including continuation of long-term monitoring, improved standardization of evaluation metrics, implementing adaptive management experiments to identify causal relationships, development of more robust analytical methods, use of historical data sources, and refining techniques to realistically convey management options to stakeholders.
The extended peridynamic model for elastoplastic and/or fracture problems
Authors: Li Wei‐Jian , You Tao , Ni Tao , Zhu Qi‐Zhi , Hien Poh Leong 
Published: June 2022

AbstractThe strain‐based implementation method for the extended peridynamic model (XPDM) resolves the limitation of standard models where only a fixed Poisson's ratio can be achieved. In this contribution, the XPDM formulation is extended to include bond breakage and/or plasticity mechanisms. The elastoplastic and bond breakage algorithms are elaborated. To capture the fracture process, a shear mechanism is now incorporated to the bond breakage response, in addition to the standard stretching failure mode. It is shown that the shear mechanism is required to accurately reproduce mixed mode fracture behavior observed experimentally. To demonstrate the predictive ability of the strain‐based XPDM, a wide range of quasi‐static and dynamic loading conditions, for both brittle and elasto‐plastic materials, is considered against experimental results or practical engineering scenarios.
Investigation on dynamic strength of 3D‐printed continuous ramie fiber reinforced biocomposites at various strain rates using machine learning methods
Authors: Cai Ruijun , Lin Hao , Cheng Ping , Zhang Zejun , Wang Kui , Peng Yong , Wu Yuankai , Ahzi Said 
Published: June 2022

Abstract3D‐printed continuous natural fiber reinforced biocomposites have promising prospects due to their environmental friendliness and suitable mechanical properties. Understanding the dynamic mechanical properties of 3D‐printed biocomposites is essential to expand their application. In this study, the continuous ramie fiber reinforced biocomposites (CRFRC) with different layer thicknesses and hatch spacings were fabricated via 3D printing technique with microstructure characterized. In addition, the dynamic strengths of 3D‐printed CRFRC at four strain rates were investigated. The experimental results exhibited that the printing parameters presented nonlinear and interactive influences on the dynamic strength of CRFRC. Given this circumstance, machine learning methods were employed to link the dynamic strength of 3D‐printed CRFRC with different printing parameters. The experimental data were used to train, calibrate, and validate the machine learning models. The trained models were then utilized to predict the dynamic strength of CRFRC printed using different conditions. Behaviors under multiple strain rates were investigated over the whole parameter space. A good agreement was found between experimental results and predictions. Based on the prediction results, the relationships between parameters, microstructural characteristics and dynamic strength of printed CRFRC were quantitatively analyzed.
Fetal and neonatal brain injury in twins complicated by twin anemia polycythemia sequence
Authors: Rosen Hadar , Silber Ronit , Schwartz Anat , Avnet Hagai , Lipitz Shlomo , Shrot Shai , Hoffmann Chen , Weisz Boaz , Yinon Yoav 
Published: June 2022

AbstractObjectivesTo determine the rate of fetal and neonatal brain lesions and define risk factors for such lesions in pregnancies complicated by Twin Anemia Polycythemia Sequence (TAPS).MethodsA retrospective cohort study of monochorionic twin pregnancies which were diagnosed with TAPS in a single tertiary medical center between 2013 and 2021. Pregnancies were followed with fetal brain neurosonogram every 2 weeks and fetal brain MRI (magnetic resonance imaging) was performed when indicated at 28–32 weeks of gestation; post‐natal brain imaging included neonatal brain ultrasound. Pregnancies with pre‐ and post‐natal brain lesions were compared to those without such findings.ResultsOverall, 23 monochorionic diamniotic pregnancies were diagnosed with TAPS over the study period resulting in perinatal survival of 91.3% (42/46). In 6/23 (26%) pregnancies and 7/46 (15.2%) fetuses pre‐ or post‐natal brain lesions were detected, of whom five were the polycythemic twins and two were the anemic twins. Brain findings included intra‐cerebral hemorrhage and ischemic lesions and were diagnosed prenatally in 6/7 (85.7%) cases. No risk factors for severe brain lesions were identified.ConclusionsTAPS may place the fetuses and neonates at increased risk for cerebral injuries. Incorporation of fetal brain imaging protocols may enhance precise prenatal diagnosis and allow for accurate parental counseling and post‐natal care.
Validity of claims data for identifying cancer incidence in the Japan public health center‐based prospective study for the next generation
Authors: Ihira Hikaru , Goto Atsushi , Yamagishi Kazumasa , Iso Hiroyasu , Iwasaki Motoki , Sawada Norie , Tsugane Shoichiro ,   JPHC‐NEXT Study Group
Published: June 2022

AbstractPurposeThis study determined the validity of claims‐based definitions for identifying the incidence of total and site‐specific cancers in a population‐based cohort study.MethodsClaims data were obtained for 21 946 participants aged 40–74 years enrolled in the Japan Public Health Center‐based Prospective Study for the Next Generation. We defined total and site‐specific cancer incidence using combinations of codes from claims data, including diagnosis and procedure codes for cancer therapy. Data from the cancer registry were used as the gold standard to evaluate validity.ResultsAmong 21 946 participants, 454 total, 89 stomach, 67 colorectal, 51 lung, 39 breast and 99 prostate invasive cancer cases were newly diagnosed in the cancer registry. For invasive cancer, the sensitivity and specificity of the definition that combined codes for diagnosis and procedures for cancer therapy were 87.0% and 99.4% for total, 88.8% and 99.9% for stomach, 80.6% and 99.9% for colorectal, 86.3% and 99.9% for lung, 100% and 99.9% for breast and 91.9% and 99.9% for prostate cancer, respectively. Furthermore, for invasive and/or in situ cancer, the sensitivity and specificity of the definition were 84.5% and 99.5% for total, 66.7% and 99.9% for colorectal and 100% and 99.9% for breast cancer.ConclusionsOur findings suggest that claims‐based definitions using diagnosis and procedure codes generally have high validity for total, stomach, lung, breast and prostate cancer incidence, but may underestimate colorectal cancer incidence.
Effects of yoga on depressive symptoms, anxiety, sleep quality, and mood in patients with rheumatic diseases: Systematic review and meta‐analysis
Authors: de Orleans Casagrande Pedro , Coimbra Danilo Reis , de Souza Loiane Cristina , Andrade Alexandro 
Published: June 2022

AbstractObjectiveTo investigate the effects of yoga on depressive symptoms, anxiety, sleep quality, and mood of patients with rheumatic diseases through a systematic literature review with meta‐analysis.Literature SurveyThis review followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) Statement and the Cochrane recommendations and risk of bias tool. The study was registered in the International Prospective Register of Systematic Reviews (PROSPERO). Studies were selected using the PICOS (participants, intervention, comparison, outcome, and study) strategy. Searches were carried out until March 2022 and performed in Web of Science, PubMed, SportDiscus, Scopus, Cochrane, and EBSCO databases.MethodologyData were extracted to identify the differences between yoga and control and exercise groups and effect sizes.SynthesisIn total, 27 studies were included for qualitative analysis and 18 for meta‐analysis. The studies found investigated yoga in patients with osteoarthritis, fibromyalgia, rheumatoid arthritis, and chronic fatigue syndrome. Regarding the risk of bias, the majority of studies showed a high risk or uncertain risk of bias in several criteria. Regarding the meta‐analysis, yoga was favored to decrease depressive symptoms (standard mean difference [SMD]:−0.88; 95% confidence interval [CI]:−1.42; −0.34), anxiety (SMD: −0.51; 95% CI = −0.81 to −0.20), and improve sleep quality SMD = −0.96; 95% CI = −1.36 to −0.56). No differences were found between yoga and other exercise modalities in depression (p < .01).ConclusionsYoga is effective in improving depression, anxiety, and sleep quality of patients with rheumatic diseases. However, research in this field still needs further studies, because of methodological issues in the studies and a reduced number of studies conducted on each rheumatic disease and on the effects of yoga on each variable.
Moderators of the association between stigma and psychological and cancer‐related symptoms in women with non‐small cell lung cancer
Authors: Snyder Stella , Kroll Juliet L. , Chen Aileen B. , Antonoff Mara B. , Yang Claire Chunyi , Milbury Kathrin 
Published: June 2022

AbstractObjectiveLung cancer patients, particularly women, are vulnerable to experience disease‐related stigma, which is linked to greater psychological distress and worse treatment outcomes. To inform future stigma‐resilience interventions, we examined if mindfulness, self‐compassion, and social support might buffer the associations between perceived lung cancer stigma and psychological and cancer‐related symptoms.MethodsIn this cross‐sectional study, women with recently diagnosed non‐small cell lung cancer undergoing cancer treatment completed measures of Cataldo Lung Cancer Stigma Scale, depressive (Center for Epidemiologic Studies Depression Scale), stress (Impact of Events Scale) and cancer‐related (MD Anderson Symptom Inventory‐Lung Cancer) symptoms, mindfulness (Mindful Attention Awareness Scale), self‐compassion (Self‐Compassion Scale), and social support (Social Provisions Scale).ResultsThe sample included 56 women (mean age = 65 years; 71% non‐Hispanic White; 50% college educated; 74% advanced stage) who had consented to participate in an online support group study. Most (70%) had a smoking history and reported moderate levels of stigma (M = 36.28, SD = 10.51). Based on general linear modeling, mindfulness moderated the associations between stigma and depressive symptoms (F = 5.78, p = 0.02), cancer‐related stress (F = 12.21, p = 0.002), and cancer‐related symptom severity (F = 4.61, p = 0.04), such that, only for women scoring low in mindfulness, the associations between stigma and symptoms were significant. For those scoring high in mindfulness, the associations between stigma and symptoms were not significant supporting a buffering effect. Self‐compassion and social support did not significantly moderate the stigma and symptom associations.ConclusionsHigher levels of mindfulness may protect women from psychological and cancer‐related symptoms typically associated with the stigmatizing experience of a lung cancer diagnosis. Yet, longitudinal studies and randomized controlled designs are needed to identify mindfulness as a causal protective factor.
Considerations for developing supportive care interventions for survivors of head and neck cancer: A qualitative study
Authors: Oswald Laura B. , Arredondo Brandy , Geiss Carley , Vigoureux Taylor F. D. , Hoogland Aasha I. , Chung Christine H. , Muzaffar Jameel , Patel Krupal B. , Gonzalez Brian D. , Jim Heather S. L. , Kirtane Kedar 
Published: June 2022

AbstractObjectiveThis study aimed to describe considerations for developing supportive care interventions targeted to head and neck cancer (HNC) survivors.MethodsOne‐time semi‐structured interviews (N = 33) were conducted with HNC survivors who had recently finished treatment (n = 20) and HNC providers (e.g., physicians, nurses; n = 13). Interviews were transcribed verbatim and coded using inductive applied thematic analysis techniques to identify themes.ResultsHNC survivors (75% male; M = 61 years old) and providers (54% physicians; 62% female) were unanimously supportive of developing HNC‐specific supportive care interventions. Participants described potential benefits of offering interventions at various points throughout the HNC treatment and survivorship trajectory rather than at a single critical time. Many participants preferred group‐based interventions because of the high value of peer‐support. Others described how group interventions may not be appropriate for all HNC survivors due to risks for negative social comparisons and exacerbated anxiety. Participants suggested topics that should be addressed in HNC‐specific interventions including education about acute and long‐term side effects, symptom management, nutritional support, relationship/social role changes, grief/loss, and fear of recurrence.ConclusionsHNC‐specific supportive care interventions are critically needed, as survivors experience persistent symptoms and distinct psychosocial concerns that impact quality of life. Findings from this study can inform the development of supportive care interventions targeted to the unique psychosocial concerns of HNC survivors.