bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validating elements of organisational maintenance policy for maintenance management of public buildings in Nigeria
Authors: Ogunbayo Babatunde Fatai , Aigbavboa Clinton Ohis , Thwala Wellington Didibhuku , Akinradewo Opeoluwa Israel , Edwards David 
Published: June 2022

PurposeMaintenance policy is an element of building maintenance management that deals with organisation policy, planning and procedures, and delineates how maintenance units in an organisation will manage specific building components, auxiliary facilities and services. Given this contextual setting, this study investigates whether organisational maintenance policies (OMPs) utilised in developed countries are relevant in developing countries – using Nigeria as a case study exemplar.Design/methodology/approachAn empirical research design (using deductive reasoning) was implemented for this research. Specifically, a Delphi study conducted revealed 23 elements that impact OMP development in Nigeria.FindingsOf these twenty elements, six had a very high impact on maintenance management (VHI: 9.00–10.00), nine variables had a high impact (HI: 7.00–8.99) and eight other variables scored a medium impact (MI: 5.00–6.99). Emergent findings reveal that the elements of organisational maintenance policy that engender effective building maintenance management include preparation of safety procedure, optimisation of the maintenance policy, optimisation of the maintenance action plan, well-defined priority system, risk factor establishment, suitable maintenance procedures and a clearly delineated process.Practical implicationsThe study findings will guide policymakers in identifying the main elements required in maintenance policies development towards making national public asset preservation and economic gains. Also, the content of the future educational curriculum on maintenance management study will be more receptive to the body of knowledge and the built environment industry.Originality/valueCumulatively, the research presented illustrates that these elements replicate those adopted in other countries and that effective maintenance management of public buildings is assured when these elements are integral to the development of an OMP.
Enterprise social media platforms for coping with an accelerated digital transformation
Authors: Feitosa Jorge Leandro , Mosconi Elaine , Santa-Eulalia Luis Antonio 
Published: June 2022

Purpose
The purpose of this paper is to investigate how to support small organizations to navigate the context of an accelerated Digital Transformation using Enterprise Social Media platforms, in response to external contingencies, such as the COVID-19 pandemic.

Design/methodology/approach
A longitudinal action research study, supported by an exploratory analysis that follows a hybrid approach of deductive and inductive reasoning, has been conducted in the context of a small organization. Several data collection techniques were used for context understanding and problem-solving.

Findings
Findings suggest that value creation related to the use of Enterprise Social Media platforms supports small organizations in this accelerated context of Digital Transformation. Value perception is central in overcoming adoption barriers and achieving sustainable use of these platforms in daily basis activities, especially in remote working. External pressures, like those imposed by the COVID-19 pandemic, play an important role in catalyzing digital initiatives.

Research limitations/implications
As the main limitations to this paper, we highlight the study of a single organization in a specific context and the number of actors involved; hence, there is room to extend the study to other industries, organization sizes and contexts.

Practical implications
This paper provides managers with insights into how to conduct their Enterprise Social Media initiatives in a turbulent environment, highlighting their key success elements, and their potential to create value for their organizations and stakeholders. Furthermore, managers could explore the potential of Enterprise Social Media platforms to support organizations in the Digital Transformation journey.

Social implications
Small organizations play an important role in generating wealth for nations around the world. However, governments encounter difficulties in supporting the Digital Transformation of this type of organization. This paper provides insights into how to use an affordable and intuitive technology to include this type of organization in the Digital Transformation journey.

Originality/value
A long-term study of Enterprise Social Media is recommended, but quite rare in the Information Systems literature. This study adopts a longitudinal investigation to analyze the use of Enterprise Social Media to support a small organization to adapt, in balance with their internal and external contingencies, providing a further contribution to the contingency theory. This research also adds contributions to the sociotechnical system perspective, analyzing the deep imbrication between social and technical subsystems in the required organizational change, supporting a small organization for coping with the effects of the COVID-19 pandemic.
Identification of sulfate‐reducing magnetotactic bacteria via a group‐specific 16S rDNA primer and correlative fluorescence and electron microscopy: Strategy for culture‐independent study
Authors: Li Jinhua , Liu Peiyu , Menguy Nicolas , Benzerara Karim , Bai Jinling , Zhao Xiang , Leroy Eric , Zhang Chaoqun , Zhang Heng , Liu Jiawei , Zhang Rongrong , Zhu Kelei , Roberts Andrew P. , Pan Yongxin 
Published: June 2022

AbstractMagnetotactic bacteria (MTB) biomineralize intracellular magnetic nanocrystals and swim along geomagnetic field lines. While few axenic MTB cultures exist, living cells can be separated magnetically from natural environments for analysis. The bacterial universal 27F/1492R primer pair has been used widely to amplify nearly full‐length 16S rRNA genes and to provide phylogenetic portraits of MTB communities. However, incomplete coverage and amplification biases inevitably prevent detection of some phylogenetically specific or non‐abundant MTB. Here, we propose a new formulation of the upstream 390F primer that we combined with the downstream 1492R primer to specifically amplify 1100‐bp 16S rRNA gene sequences of sulfate‐reducing MTB in freshwater sediments from Lake Weiyanghu, Xi'an, northwestern China. With correlative fluorescence in situ hybridization and scanning/transmission electron microscopy, three novel MTB strains (WYHR‐2, WYHR‐3 and WYHR‐4) from the Desulfobacterota phylum were identified phylogenetically and structurally at the single‐cell level. Strain WYHR‐2 produces bullet‐shaped magnetosome magnetite, while the other two strains produce both cubic/prismatic greigite and bullet‐shaped magnetite. Our results expand knowledge of bacterial diversity and magnetosome biomineralization of sulfate‐reducing MTB. We also propose a general strategy for identifying and characterizing uncultured MTB from natural environments.
Comparative analysis of aged documents by desorption electrospray ionization–Mass spectrometry (DESI‐MS) imaging
Authors: Sun Qiran , Luo Yiwen , Wang Yachen , Zhang Qinghua , Yang Xu 
Published: June 2022

AbstractDocument dating is an important and challenging task in the field of forensic science. With the development of analytical techniques, related methods are emerging for document dating studies. Desorption electrospray ionization–mass spectrometry (DESI‐MS) is an ambient ionization‐MS technique that has been applied in the forensic discrimination of inks. This study focused on utilizing DESI‐MS to distinguish between ink entries of different ages. Blue ballpoint ink and black gel ink samples were artificially aged by heat and light exposure and then screened by DESI‐MS in the positive ion mode, with a methanol–water‐formic acid solution (90:10:0.1%, v/v/v) as the desorption solvent. As a result, the artificially aged ink samples were directly differentiated from the reference ones in the chemical images of age‐dependent compounds such as basic dyes or polyethylene glycol derivatives. The amount of ethoxylated fatty amine surfactants in copy paper was also found to decrease after artificial aging. Moreover, this method enabled us to visualize the differences between the composition of naturally aged and fresh ink samples. It has been proven to cause no apparent destruction of the samples. The identification of chronological changes in document materials suggests that the DESI‐MS method is a promising approach for relative document dating.
A Structural Interpretation Model and Restoration of the Mesozoic Proto‐basin for the Kuqa Depression, Tarim Basin
Authors: QI Jiafu , LI Yong , XU Zhenping , YANG Shujiang , SUN Tong 
Published: June 2022

AbstractA thrust‐fold belt consisting of a series of thrusts and buckling folds developed in the Mesozoic and Cenozoic strata within the Kuqa Depression, Tarim Basin. In this study, a structural interpretation model of the Kuqa Depression is established and the Mesozoic proto‐basin is reconstructed on the basis of outcrop geology along the basin margin, seismic, well‐log and CEMP data. The model is called ‘delaminate contractional deformation’, which emphasizes the decoupling between the Cenozoic, Mesozoic, pre‐Mesozoic and the basin‐basement within the Kuqa Depression, but there is no unified detachment. The model has a shortening amount ranging from 12 km to 16 km and the depth involved in contractional deformation ranges from 21 km to 28 km. A prototype of the Mesozoic basin reconstructed by interpretation model is a sub‐basin superposed on the transitional zone between the uplift at the northern edge of the Tarim Craton and the southern Tianshan orogenic wedge formed in the Hercynian orogeny. Lithospheric thermal and crustal isostatic activity after the Hercynian orogeny maybe the controlling dynamic factors of basin subsidence during the Mesozoic and early Cenozoic, the difference in rock mechanical properties between different levels, craton and orogenic wedge being the major cause of the ‘delaminate contractional deformation’ during the Himalayan orogeny.
Metformin for the prevention of clozapine‐induced weight gain: A retrospective naturalistic cohort study
Authors: Stogios Nicolette , Maksyutynska Kateryna , Navagnanavel Janani , Sanches Marcos , Powell Valerie , Gerretsen Philip , Graff‐Guerrero Ariel , Chintoh Araba F. , Foussias George , Remington Gary , Hahn Margaret K. , Agarwal Sri Mahavir 
Published: June 2022

AbstractObjectiveClozapine is presently the sole antipsychotic with an indication for treatment‐resistant Schizophrenia, but is associated with significant weight gain and other metabolic aberrations. This retrospective chart review aimed to evaluate the effectiveness of adjunctive metformin in preventing clozapine‐induced weight gain.MethodsWe conducted a retrospective chart review of patients newly initiated on clozapine at the Centre for Addiction and Mental Health in Canada, from November 2014 to April 2021. Our primary outcome was body weight at 6 and 12 months after clozapine initiation. Other metabolic parameters served as secondary outcomes.ResultsAmong 396 patients (males: 71.5%, mean age: 42.8 years) initiated on clozapine, 69 were on metformin or prescribed it ≤3 months after clozapine initiation. The clozapine+metformin group demonstrated less weight gain compared with the clozapine‐only group at 6 months (clozapine+metformin: −0.15 kg [SE = 1.08] vs. clozapine‐only: 2.99 kg, SE = 0.54) and 12 months after clozapine initiation (clozapine+metformin: −0.67 kg, SE = 1.22 vs. clozapine‐only: 4.72 kg, SE = 0.67). Adaptive changes were also observed for fasting glucose (F = 3.10, p = 0.046) and triglycerides (F = 8.56, p < 0.001) in the clozapine+metformin group compared with clozapine only.ConclusionIn this large retrospective naturalistic cohort study, co‐prescription of clozapine and metformin was associated with less weight gain and related metabolic dysfunction at 6 and 12 months after initiation versus clozapine alone. These findings provide evidence for the effectiveness of metformin in preventing clozapine‐induced weight gain; larger randomized controlled trials are needed to confirm these results.
Electrophysiological resting‐state hyperconnectivity and poorer behavioural regulation as predisposing profiles of adolescent binge drinking
Authors: Antón‐Toro Luis F. , Bruña Ricardo , Del Cerro‐León Alberto , Shpakivska Danylyna , Mateos‐Gordo Patricia , Porras‐Truque Claudia , García‐Gómez Raquel , Maestú Fernando , García‐Moreno Luis Miguel 
Published: June 2022

AbstractAdolescent Binge Drinking (BD) has become an increasing health and social concern, with detrimental consequences for brain development and functional integrity. However, research on neurophysiological and neuropsychological traits predisposing to BD are limited at this time. In this work, we conducted a 2‐year longitudinal magnetoencephalography (MEG) study over a cohort of initially alcohol‐naïve adolescents with the purpose of exploring anomalies in resting‐state electrophysiological networks, impulsivity, sensation‐seeking, and dysexecutive behaviour able to predict future BD patterns. In a sample of 67 alcohol‐naïve adolescents (age = 14.5 ± 0.9), we measured resting‐state activity using MEG. Additionally, we evaluated their neuropsychological traits using self‐report ecological scales (BIS‐11, SSS‐V, BDEFS, BRIEF‐SR and DEX). In a second evaluation, 2 years later, we measured participant's alcohol consumption, sub‐dividing the original sample in two groups: future binge drinkers (22 individuals, age 14.6 ± 0.8; eight females) and future light/no drinkers (17 individuals, age 14.5 ± 0.8; eight females). Then, we searched for differences predating alcohol BD intake. We found abnormalities in MEG resting state, in a form of gamma band hyperconnectivity, in those adolescents who transitioned into BD years later. Furthermore, they showed higher impulsivity, dysexecutive behaviours and sensation seeking, positively correlated with functional connectivity (FC). Sensation seeking and impulsivity mainly predicted BD severity in the future, while the relationship between dysexecutive trait and FC with future BD was mediated by sensation seeking. These findings shed light to electrophysiological and neuropsychological traits of vulnerability towards alcohol consumption. We hypothesise that these differences may rely on divergent neurobiological development of inhibitory neurotransmission pathways and executive prefrontal circuits.
Structural and functional analyses of antibodies specific for modified core N‐glycans suggest a role in TH2 responses
Authors: Plum Melanie , Tjerrild Luna , Raiber Tim , Bantleon Frank , Bantleon Sara , Miehe Michaela , Jabs Frederic , Seismann Henning , Möbs Christian , Pfützner Wolfgang , Jakob Thilo , Andersen Gregers R. , Spillner Edzard 
Published: June 2022

AbstractBackgroundImmune responses to N‐glycan structures from allergens and parasites are often associated with pronounced, high affinity IgE reactivities. Cross‐reactive carbohydrate determinants (CCDs) are constituted by modified N‐glycan core structures and represent the most frequently recognized epitopes in allergic immune responses. Although recently accepted as potentially allergenic epitopes, the biological and clinical relevance as well as structural and functional characteristics of CCD‐specific antibodies remain elusive.MethodsIn order to gain structural insights into the recognition of CCDs, two specific antibody fragments were isolated from a leporid immune repertoire library and converted into human/leporid IgE and IgG formats. The antibody formats were assessed by ELISA and surface plasmon resonance, structural and functional analyses were performed by X‐ray crystallography, mediator release, and ELIFAB assays.ResultsThe recombinant IgE exhibited highly specific interactions with different types of CCDs on numerous CCD‐carrying glycoproteins. Crystal structures of two CCD‐specific antibodies, one of which in complex with a CCD‐derived disaccharide emphasize that mechanisms of core glycan epitope recognition are as specific as those governing protein epitope recognition. The rIgE triggered immediate cellular responses via FcεRI cross‐linking and mediated facilitated antigen presentation by binding of IgE/antigen complexes to CD23, a process that also could be blocked by IgG of allergic patients.ConclusionsOur study provides evidence for the relevance of N‐glycan recognition in TH2 responses and corroborates that IgE and IgG antibodies to ubiquitous carbohydrate epitopes can be equivalent to those directed against proteinaceous epitopes with implications for diagnostic and immunotherapeutic concepts.
Longitudinal changes in fetal head biometry and fetoplacental circulation in fetuses with congenital heart defects
Authors: Ordás Polán , Rodríguez Roberto , Herrero Beatriz , Deiros Lucía , Gómez Enery , Llurba Elisa , Bartha José Luis , Antolín Eugenia 
Published: June 2022

AbstractIntroductionObjectives were to analyze changes in fetal cephalic biometry and fetoplacental circulation throughout pregnancy in fetuses with congenital heart defects.Material and methodsProspective study conducted on three university tertiary referral hospitals. Fetuses with the diagnosis of isolated congenital heart defects attending between 2014 and 2018 were included. Congenital heart defects were divided into two groups according to the oxygen supply to the central nervous system: group I (expected low placental blood content and low oxygen delivery to the brain) and group II (expected intermediate and high placental blood content). Fetal biometry and Doppler parameters were collected between 25–30 weeks of gestation and 34–40 weeks of gestation and transformed into Z scores. The results were compared with healthy controls. Finally, general linear modeling was performed to analyze repeated measurements.ResultsIn all, 71 fetuses met the inclusion criteria. Fetuses with congenital heart defects had significantly smaller head (biparietal diameter [p < 0.001], head circumference [p = 0.001]) and abdominal circumference (p < 0.001), and lower estimated fetal weight (p < 0.001) than controls. When analyzing according to congenital heart defects type, head size was significantly smaller in group I compared with group II (p = 0.04). Regarding Doppler parameters, fetuses with congenital heart defects showed higher umbilical artery pulsatility index (p < 0.001) and lower cerebroplacental ratio (p = 0.044) than controls. In group I, umbilical artery pulsatility index was above the 95th centile in 15.4% of fetuses compared with 6.7% in group II and 1.9% in controls (p < 0.001); moreover, middle cerebral artery pulsatility index was below the 5th centile in 5.4% of group I fetuses compared with 0% in group II and 1.2% in controls (p = 0.011). General linear model for two measurements showed significant longitudinal changes in biometric parameters. Growth rate of fetal head through pregnancy (head circumference Z score) was lower in fetuses with congenital heart defects compared with controls (p = 0.043). In group I, the head circumference Z score longitudinal decrease was significantly higher than in group II (p < 0.001).ConclusionsFetuses with congenital heart defects are at risk of smaller head size and Doppler changes. Growth rate of fetal head throughout pregnancy is also affected. These findings are mainly associated with cardiac defects with expected low oxygen supply to the central nervous system.
Objectively measured physical activity during primary school physical education predicts intrinsic motivation independently of academic achievement level
Authors: de Bruijn Anne G. M. , de Greeff Johannes W. , Temlali Taha Y. , Oosterlaan Jaap , Smith Joanne , Hartman Esther 
Published: June 2022

AbstractBackgroundChildren's participation in physical education (PE) is seen as important for developing an active lifestyle and has been positively linked to academic achievement. Physical activity (PA) levels during PE are thought to be linked to PE‐motivation, although this relation is poorly understood.AimsThis study examined (1) whether children's PA‐levels during PE were predictive of their PE‐motivation and (2) whether the relation between PA‐levels and motivation was moderated by children's academic achievement. Where previous studies focused on moderate‐to‐vigorous physical activity (MVPA), disregarding the potential beneficial role of lower intensities of PA, we included MVPA, light‐intensity physical activity (LPA) and sedentary behaviour (SED).SampleIn total, 891 primary school students participated (mean age = 9.2 years).MethodsDuring one regular PE‐lesson, PA‐levels (using accelerometers) and PE‐motivation (Intrinsic Motivation Inventory) were measured. Academic achievement in reading, mathematics and spelling was measured with standardized tests.ResultsA structural equation model revealed that LPA, MVPA and academic achievement positively predicted PE‐motivation. The interaction between academic achievement and PA‐levels was not related to PE‐motivation. SED was excluded from the models due to multicollinearity.ConclusionChildren who are more engaged in LPA and MVPA and who perform better academically generally seem to be more motivated for PE, suggesting that PA‐intensity levels and PE‐motivation are bidirectionally linked. Results underline the importance of also examining LPA.
An evaluation of the impact of flipped‐classroom teaching on mathematics proficiency and self‐efficacy in Saudi Arabia
Authors: Algarni Badriah , Lortie‐Forgues Hugues 
Published: June 2022

AbstractThe flipped classroom (FC) is becoming an increasingly popular teaching method in mathematics education. However, few studies have rigorously evaluated its effectiveness, and less so in countries where students' level of mathematics achievement is low. In this study, we evaluated the impact of an FC intervention in Saudi Arabia, the country with the lowest level of maths achievement in the last iteration of the Trends International Mathematics and Science Study TIMSS . A total of 281 secondary school students received eight weeks of algebra training using either FC or traditional instruction, and were tested on algebra problems taken from past national standardised tests, as well as on a measure of self‐efficacy. Students who received the intervention showed higher self‐efficacy but no significant difference in maths achievement was observed. Students' and teachers' perceptions of the intervention were positive.Practitioner notesWhat is already known about this topic

The flipped classroom is an increasingly popular teaching method in mathematics education.
There is evidence that the method is beneficial for students.
However, there have been very few rigorous evaluation studies of flipped classrooms and most were conducted in the US, Taiwan and China.
Whether the beneficial impact of flipped classrooms can be generalised to other countries, particularly countries with low proficiency in mathematics, remains unclear.
What this paper adds

We evaluated the impact of the flipped classroom in Saudi Arabia, a country with low proficiency in mathematics and limited technological resources.
We used a rigorous design (with a control group) and educationally relevant outcome measures.
We found that a flipped classroom can have a positive impact on students' self‐efficacy, and that the method was perceived positively by both teachers and students.
Based on interview data, we also documented the perceptions and concerns of the participating teachers.
Implications for practice and/or policy

Flipped classrooms showed promising results in a context which differs markedly from previous evaluations, suggesting that the method can be beneficial in a range of contexts.
This positive impact was observed despite the intervention being relatively short (six weeks) and implemented by teachers previously unfamiliar with the flipped classroom method.