bluuebunny/crossref_metadata_2025_split huggingface dataset:
EFEKTIVITAS KOMUNIKASI VIRTUAL PEMBELAJARAN DARING DALAM MASA PSBB (Studi Kasus Pembelajaran Jarak Jauh Produktif Siswa SMK Negeri 2 Banjarmasin)
Authors: Shadiqien Shen 
Published: February 2022

Pemberlakuan pembelajaran jarak jauh karena pandemi wabah COVID-19 dan pembelakuan pembatasan sosial berskala besar atau PSBB di Kota Banjarmasin mengakibatkan salah satu institusi yaitu institusi pendidikan mewajibkan pelaksanaan kegiatan kerja dan pembelajaran secara jarak jauh dengan menggunakan teknologi internet bagi guru dan siswa peserta pembelajaran. Penggunaan instrumen aplikasi video teleconference dalam pembelajaran dianggap lebih mendekati mewakili proses interaksi pembelajaran secara persuasif oleh pengajar terhadap peserta didiknya dengan komunikasi virtual melalui fasilitas teknologi internet dengan video teleconference. Namun salah satu ciri dari pembelajaran jarak jauh adalah terpisahnya antara pengajar dan siswa baik secara ruang dan waktu sehingga membutuhkan perencanaan yang sistematis dan terdiri dari persiapan, dan presentasi bahan ajar, pengawasan dan dukungan pembelajaran siswa, yang dicapai dengan menjembatani jarak fisik antara siswa dan guru melalui media teknis yang tepat. Fakta di lapangan pembelajaran daring secara video teleconference sering tidak terpenuhi sesuai jumlah rombongan belajar dalam satu kelas, sehingga masalah tersebut menjadi kendala dalam melakukan penilaian secara menyeluruh oleh guru terhadap siswa dalam satu rombongan belajar. Meninjau permasalahan tersebut, perlu untuk mengetahui dampak komunikasi virtual dalam pembelajaran daring, menelusuri kendala dan permasalahan secara teknis yang dilaksanakan menggunakan teknologi komunikasi virtual jarak jauh secara realtime atau non-realtime serta mengidentifikasi pola-pola pembelajaran yang sesuai dan tepat sesuai kondisi siswa Kata kunci : Pembelajaran Daring;Komunikasi Virtual.
Significant brainstem dysfunction in neonates with myelomeningoceles: a comparison of prenatal versus postnatal closure
Authors: Grabb Paul A. , Vlastos Emmanuel J. , Lundy Paige A. , Partington Michael B. 
Published: February 2022

OBJECTIVE
The purpose of this study was to compare the incidence of significant brainstem dysfunction (SBD) in neonates with myelomeningocele who have been treated with prenatal versus postnatal closure at a single institution.

METHODS
The records and imaging of all children undergoing either prenatal (n = 27) or postnatal (n = 60) closure of myelomeningocele at the authors’ institution from December 2014 through May 2021 were reviewed. SBD, fetal ventricular size, gestational age at fetal imaging and delivery, postnatal ventricular size, need for and type of hydrocephalus treatment, spinal neurological level at birth, anatomical Chiari severity, death, and prenatal or postnatal repair were factors recorded. SBD was defined by need for airway surgery or gastrostomy tube, or endotracheal intubation because of apnea, aspiration, or airway control problems. Comparisons between prenatal and postnatal cohorts and between the cohorts with and without SBD were performed.

RESULTS
SBD occurred in 25% and 0% of neonates who underwent postnatal and prenatal closure, respectively. There were no differences in fetal ventricular size or spinal neurological level between the prenatal and postnatal cohorts or between those with or without SBD. Anatomical severity of the Chiari malformation after birth was worse in the postnatal cohort. Hydrocephalus treatment was required in 70% and 33% of infants who underwent postnatal and prenatal closure, respectively. All three deaths were in the postnatal group from SBD.

CONCLUSIONS
Prenatal closure of myelomeningocele is associated with a significant reduction in SBD.
FREKUENSI PENIMBANGAN DENGAN STATUS GIZI BALITA
Authors: Amir Aswita , Rochimiwati Siti Nur , Asbar Ramlan , Toro Riana Arfani 
Published: February 2022

Background: Nutritional status is a measure of the state of the body based on food consumption and the use of nutrients in the body. The monthly growth monitoring activities performed every month in Posyandu by looking at the growth monitoring through KMS, healthy childrens will show Weight gain every month follows the growth line and provides information on the nutritional status of children because the parents and children's visit is actively expected to help the parents in stimulating the development of children, but on the other hand the parent activity can make the parents become inactive in the visit to Posyandu.Objectives: The study objective was to analyze the relation between the frequency of weighing with nutritional status of children.Methods: The samples was children aged 06-59 month which amount 107 people obtained by using simple random sampling technique. Frequeny of weighing was known from the questionnaire which has been filled by the respondent and matched with KMS or Posyandu notebook. Children nutritional status was calculated by using WHO Anthro 2005 based on index of BB/U. This study used chi square test with SPSS program and the data was presented in the form of frequency distribution tables and narratives.Results: The result of study showed that 55.1% of samples had a frequency of weighing ≥ 4 times. Sample with good nutritional status equal to 77,6%. The result of statistical test with ρ value 0,079 (ρ> 0,050) shows that there is no relation between frequency of weighing with nutritional status of children.Conclusions: There is no relation between frequency of weighing and nutritional status of children.Keywords: frequency of weighing, nutritional status, children
AUDIT SISTEM MANAJEMEN KESELAMATAN DAN KESEHATAN KERJA DI PT BUANA CENTRA SWAKARSA DI KABUPATEN BOGOR
Authors: Gagat Rakasiwi Aryo , Ginanjar Rubi , Listyandini Rahma 
Published: February 2022

Sistem Manajemen K3 (SMK3) menurut Peraturan Pemerintah No.50 Tahun 2012 adalah bagian dari sistem manajemen perusahaan secara keseluruhan dalam rangka pengendalian risiko yang berkaitan dengan kegiatan kerja guna terciptanya tempat kerja yang aman, efisien dan produktif. Tujuan penelitian yaitu sebagai evaluasi pada penerapan SMK3 di PT Buana Centra Swakarsa. Penelitian ini menggunakan metode kualitatif deskriptif dengan melakukan pendekatan Action Research, Pengambilan data dilakukan menggunakan lembar pedoman checklist dengan proses observasi secara langsung, dan wawancara menggunakan pedoman wawancara kepada informan kunci sebagai objek penelitian. Analisa yang digunakan berupa analisis statistik deskriptif. Dari penelitian ini menunjukan penerapan Sistem Manajemen K3 yang telah diterapkan PT Buana Centra Swakarsa dengan kriteria tingkat lanjutan dengan penilaian sebanyak 12 elemen dan 166 poin kriteria penilaian, setelah dilakukan penilaian SMK3 telah terpenuhi sebanyak 153 poin dari 166 poin kriteria penilaian bila dipersentasekan sebesar 92,1% dengan kategori yang memuaskan, meskipun dalam penerapannya masih ada beberapa kekurangan sebanyak 13 poin kriteria bila dipresentasikan sebesar 7,83%. Berdasarkan PP No.50 Tahun 2012 kategori sebesar (80-100%) merupakan kategori yang memuaskan. Kesimpulan dari penelitian ini yaitu dalam penerapan SMK3 di perusahaan PT Buana Centra Swakarsa terbilang sudah memuaskan, akan tetapi di lapangan masih harus melakukan beberapa upaya peningkatan terutama dalam penyediaan APD sesuai dengan kebutuhan dibidangnya terutama bagian workshop guna mengurangi potensi kecelakaan kerja maupun mencegah PAK (Penyakit Akibat Kerja) akibat dari proses kerja.
PENERAPAN PROGRAM NEW NORMAL NEW LIFE STYLE DALAM PENCEGAHAN COVID-19 BERBASIS DARING DI KELURAHAN TANAH SAREAL
Authors: Putri Anggita , Asnifatima Andi 
Published: February 2022

Masalah kesehatan seringkali muncul di masyarakat tanpa disadari dan dikethui penyebabnya. Hal tersebut terjadi karena faktor pengetahuan masyarakat yang masih rendah tentang kesehatan di masyarakat. Dalam pandemi Covid-19 ini banyak masyarakat yang tidak menerapkan protokol kesehatan, padahal pemutus rantai penyebaran Covid-19 bisa dimulai dari menerapkan protokol kesehatan dalam kehidupan sehari-hari. Tujuan pengabdian masyarakat adalah untuk meningkatkan pengetahuan dan kesadaran masyarakat terutama pada masyarakat usia 17-25 tahun mengenai pentingnya menerapkan protokol kesehatan dalam keshidupan sehari-hari dan adaptasi kebiasaan baru guna memutus rantai penyebaran Covid-19. Metode kegiatan pengabdian kepada masyarakat yang dilakukan di Gang Mesjid rt 001 / rw 004 Kelurahan tanah Sareal Kota Bogor yaitu mengedukasi mengenai kesehatan kepada masyarakat usia 17-25 tahun tentang adaptasi kebiasaan baru. Hasil kegiatan pengabdian masyarakat ini adalah menerapkan protokol kesehatan, pentingnya menggunakan masker, social distancing, dan adaptasi kebiasaan baru.
Constitutional Compliance Solution to Law Testing Rulings in the Constitutional Court
Authors: Sulistyowati Tri , Ridho Ali , Nasef M Imam 
Published: February 2022

One of the current constitutional issues in Indonesia is the non-compliance of the decision to immediately follow up the decision of the Constitutional Court, which is final. This paper aims to analyze forms of non-compliance with the decision of the Constitutional Court and create a model that is expected to be a solution to the problem. This type of research is juridical normative by using secondary data processed by editing and systematization techniques. The results showed the form of non-compliance of the decision of the Constitutional Court by the addresat of the decision is manifested in 3 (three) forms, namely normative, praxis, and normative and praxis forms. There are three proposed state-regulation solutions, namely judicial deferral by limiting the time of action, re-affirmation of judicial restraint, collaborative action, and collective awareness between state institutions.
Guarantee Of Worker Rights During The Covid 19 Pandemic
Authors: Agustanti Rosalia Dika , Wahyuningsih Yuliana Yuli , - Satino 
Published: February 2022

This research discusses the rights of workers / laborers during the COVID-19 pandemic and what if the employers do not meet these rights. Problem which is more in-depth about the employment that emerged during this pandemic, namely the occurrence of massive layoffs. The research was conducted using the Normative Juridical method. By applying the Statute Approach, Conceptual Approach, and Case Approach, the results show that employers have not been able to fulfill workers / labor rights during the COVID-19 pandemic. There are companies that have not implemented the clean lifestyle and occupational health standards K3 protection such as masks, hand sanitizer and personal protective equipment. Prevention and handling policies are still not optimal, the principle of maintaining social distancing has not been implemented optimally, there are still many workers who are jostling for work when they come to work, not to mention during the trip to work in public transportation. This situation makes them vulnerable to infection. However, they still have to go to work because of the risk of losing their income. Efforts that can be made if wages are not paid are to take the route or methods as regulated in Law Number 2 of 2004 concerning Settlement of Industrial Relations Disputes. The basis of a dispute between a worker/ laborer and an entrepreneur is a dispute over rights.
DETERMINASI KEBIJAKAN DIVIDEN PADA PERUSAHAAN LQ45 YANG TERDAFTAR DI BURSA EFEK INDONESIA
Authors: Sabtohadi Joko , Nurfadillah Mursidah , Anitra Ver 
Published: February 2022

Penelitian ini bertujuan untuk menganalisis faktor yang mempengaruhi kebijakan dividen pada perusahaan LQ 45 yang Listing di Bursa Efek Indonesia. Jenis penelitian yang di gunakan adalah jenis penelitian kuantitatif dengan menggunakan Metode porpusive sampling untuk menentukan sampel. Penelitian ini menggunakan 45 perusahaan LQ45 sebagai populasi dan terdapat 24 sampel perusahaan LQ45 yang terdaftar di BEI periode 2016-2019. Data ini diolah dengan menggunakan aplikasi SPSS dan metode analisis dalam penelitian ini menggunakan Regresi Linier Berganda. Hasil analisis menunjukkan bahwa secara simultan semua variabel bebas berpengaruh terhadap kebijakn dividen, namun secara parsial hanya profitabilitas yang berpengaruh signifikan
Oligodendroglia Generated From Adult Rat Adipose Tissue by Direct Cell Conversion
Authors: Vellosillo Lara , Pascual-Guerra Jorge , Muñoz Maria Paz , Rodríguez-Navarro José Antonio , González-Nieto Daniel , Barrio Luis Carlos , Lobo Maria del Val Toledo , Paíno Carlos Luis 
Published: February 2022

Obtaining oligodendroglial cells from dispensable tissues would be of great interest for autologous or immunocompatible cell replacement therapy in demyelinating diseases, as well as for studying myelin-related pathologies or testing therapeutic approaches in culture. We evaluated the feasibility of generating oligodendrocyte precursor cells (OPCs) from adult rat adipose tissue by expressing genes encoding transcription factors involved in oligodendroglial development. Adipose-derived mesenchymal cells were lentivirally transduced with tetracycline-inducible Sox10, Olig2, Zfp536, and/or Nkx6.1 transgenes. Immunostaining with the OPC-specific O4 monoclonal antibody was used to mark oligodendroglial induction. O4- and myelin-associated glycoprotein (MAG)-positive cells emerged after 3 weeks when using the Sox10 + Olig2 + Zfp536 combination, followed in the ensuing weeks by GFAP-, O1 antigen-, p75NTR (low-affinity NGF receptor)-, and myelin proteins-positive cells. The O4+ cell population progressively expanded, eventually constituting more than 70% of cells in culture by 5 months. Sox10 transgene expression was essential for generating O4+ cells but was insufficient for inducing a full oligodendroglial phenotype. Converted cells required continuous transgene expression to maintain their glial phenotype. Some vestigial characteristics of mesenchymal cells were maintained after conversion. Growth factor withdrawal and triiodothyronine (T3) supplementation generated mature oligodendroglial phenotypes, while FBS supplementation produced GFAP+- and p75NTR+-rich cultures. Converted cells also showed functional characteristics of neural-derived OPCs, such as the expression of AMPA, NMDA, kainate, and dopaminergic receptors, as well as similar metabolic responses to differentiation-inducing drugs. When co-cultured with rat dorsal root ganglion neurons, the converted cells differentiated and ensheathed multiple axons. We propose that functional oligodendroglia can be efficiently generated from adult rat mesenchymal cells by direct phenotypic conversion.
Clinical Outcomes Associated With His-Purkinje System Pacing vs. Biventricular Pacing, in Cardiac Resynchronization Therapy: A Meta-Analysis
Authors: Gui Yang , Ye Lifang , Wu Liuyang , Mai Haohui , Yan Qiqi , Wang Lihong 
Published: February 2022

AimsHis-Purkinje system pacing has recently emerged as an alternative to biventricular pacing (BIVP) in cardiac resynchronization therapy (CRT). The aim of this study was to conduct a meta-analysis comparing the clinical outcomes associated with His-Purkinje system pacing (HPSP) vs. BIVP in patients with heart failure. There is also a comparison of clinical outcomes of His-bundle pacing (HBP) and left bundle branch pacing (LBBP) in the His-Purkinje system.MethodsWe searched the Cochrane Library, Embase, and PubMed, for studies published between January 2010 and October 2021 that compared the clinical outcomes associated with HPSP vs. BIVP and HBP vs. LBBP in HPSP in patients who underwent CRT. The pacing threshold, R-wave amplitudes, QRS duration, New York Heart Association functional (NYHA), left ventricular ejection fraction (LVEF), and LV end-diastolic diameter (LVEDD) of heart failure, at follow-up, were extracted and summarized for meta-analysis.ResultsA total of 18 studies and 1517 patients were included in our analysis. After a follow-up period of 9.3 ± 5.4 months, the HPSP was found to be associated with shorter QRS duration in the CRT population compared to that in the BIVP (SMD, −1.17; 95% CI, −1.56 to −0.78; P &lt; 0.00001; I2 = 74%). No statistical difference was verified between HBP and LBBP on QRS duration (SMD, 0.04; 95% CI, −0.32 to 0.40; P = 0.82; I2 = 84%). In the comparison of HPSP and BIVP, the LBBP subgroup showed improved LVEF (SMD, 0.67; 95% CI, 0.42–0.91; P &lt; 0.00001; I2 = 0%), shorter LVEDD (SMD, 0.59; 95% CI, 0.93–0.26; P = 0.0005; I2 = 0%), and higher New York Heart Association functional class (SMD, −0.65; 95% CI, −0.86 to −0.43; P &lt; 0.00001; I2 = 45%). In terms of pacing threshold and R-wave amplitude clinical outcomes, LBBP has a lower pacing threshold (SMD, 1.25; 95% CI, 1.12–1.39; P &lt; 0.00001; I2 = 47%) and higher R-wave amplitude (MD, −7.88; 95% CI, −8.46 to −7.31; P &lt; 0.00001; I2 = 8%) performance compared to HBP.ConclusionOur meta-analysis showed that the HPSP produced higher LVEF, shorter QRS duration, and higher NYHA functional class in the CRT population than the BIVP as observed on follow-up. LBBP has a lower pacing threshold and higher R-wave amplitude. HPSP may be a new and promising alternative to BIVP in the future.
Safety and Effectiveness Outcomes of a Novel Automated Titanium Suture Fastener Device Applied for Heart Valve Surgery in an Ovine Model
Authors: Li Bin , Bai Shanshan , Yue Guangxin , Zhu Jinyan , Zhang Min , Yang Baiqing , Luo Jiafei , Sun Yang , Zhang Leisheng , Wang Xin 
Published: February 2022

ObjectiveThis study was designed to evaluate the operability, effectiveness, and safety of the automated titanium suture fastener in a preclinical ovine model in comparison with manual tying in a mitral valve annuloplasty ring implantation surgery.MethodsEighteen adult Small-tailed Han sheep were prepared for the surgery of mitral valve annuloplasty ring implantation through lateral thoracotomy under cardiopulmonary bypass (CBP). A total of 12 stitches were performed to secure an annuloplasty ring, with 6 stitches done with the automated fastener and the other 6 by manual tying. The knotting time for the automated fastener or manual tying was recorded, respectively. The firmness of knots, mitral valve integrity, biocompatibility, thrombosis, local reactions, and other aspects were also compared at follow-up time (Days 30, 60, 90, and 180).ResultsOf the 18 sheep, 16 survived to the designated endpoints and were enrolled for further analysis. Compared with the control group, the knotting time was significantly reduced with the automated fastener (p &lt; 0.01). All the annuloplasty rings were tightly secured by 6 fastener clips and 6 hand-made knots without any disengagement or displacement. All the mitral valves were intact without any defect, stenosis, prolapse, valve insufficiency, or perforation. Endothelialization was comparable between the two groups by Day 60. Small red thrombi formed at the thread end of the suture in both groups. No thrombus was found on the surface of the titanium clip. All the thrombi were within the acceptable range for the antithrombotic property. Thrombosis showed no significant difference by Day 60. No significant differences in the inflammatory response and pathological lesions were observed by Day 60. One case of diffuse renal infarction (area ratio = 20%) and 1 case of small focal renal infarction (area ratio &lt; 5%) were caused by thromboembolism.ConclusionsThe automated fastener significantly shortened the procedure time of tying knots for the implantation of the annuloplasty ring in the ovine model, with comparable safety and effectiveness as manual tying.
Association Between Arterial Stiffness and Blood Pressure Progression With Incident Hypertension: A Systematic Review and Meta-Analysis
Authors: Saz-Lara Alicia , Bruno Rosa María , Cavero-Redondo Iván , Álvarez-Bueno Celia , Notario-Pacheco Blanca , Martínez-Vizcaíno Vicente 
Published: February 2022

BackgroundArterial stiffness is an independent predictor of cardiovascular and all-cause mortality that is classically regarded as a consequence of arterial hypertension. However, a growing number of studies have shown that arterial stiffness is involved in the pathogenesis and prognosis of arterial hypertension. Thus, in this systematic review and meta-analysis, we aimed to assess whether arterial stiffness, as measured by pulse wave velocity, systolic blood pressure and diastolic blood pressure are associated with incident hypertension.MethodsThe Scopus, PubMed, Web of Science and Cochrane Library databases were searched from inception to March 30, 2021. The DerSimonian and Laird method was used to compute pooled relative risk estimates and their respective 95% confidence intervals of association between incident hypertension with pulse wave velocity, systolic blood pressure and diastolic blood pressure.ResultsOur findings provide a synthesis of the evidence supporting that the higher arterial stiffness (RR: 1.09; 95% CIs: 1.05, 1.12), systolic blood pressure (RR: 1.08; 95% CIs: 1.05, 1.10) and diastolic blood pressure (RR: 1.08; 95% CIs: 1.04, 1.12) are associated with incident hypertension in normotensive adult subjects, with similar independent predictive values. However, our results should be interpreted with caution because the meta-analyses performed showed considerable heterogeneity.ConclusionsOur results showed that higher pulse wave velocity, systolic blood pressure and diastolic blood pressure are associated with incident hypertension. These findings are of clinical importance, supporting arterial stiffness as an additional tool for the prevention of arterial hypertension and being a fundamental component to reduce cardiovascular morbidity and mortality.Systematic Review RegistrationThis study was registered in PROSPERO https://www.crd.york.ac.uk/PROSPERO/display_record.php?RecordID=236435 (Registration number: CRD42021236435).
Assessment of the Causal Effects of Obstructive Sleep Apnea on Atrial Fibrillation: A Mendelian Randomization Study
Authors: Li Yalan , Leng Yiming , Tang Haibo , Deng Peizhi , Wang Jie , Yuan Hong , Miao Rujia , Mu Ping 
Published: February 2022

BackgroundObstructive sleep apnea (OSA) and atrial fibrillation (AF) are epidemiologically correlated, but the causal relationship between them remains elusive. We aimed to explore the causal relationships between OSA and AF.MethodUsing both the Finnish biobank and publicly available genome-wide association study data (GWAS), we conducted a two-sample Mendelian randomization (MR) analysis to estimate the causal effect of OSA on AF, both in the primary analysis and replicated analysis. The inverse variance weighted MR was selected as the main method. To further test the independent causal effect of OSA on AF, we also performed multivariable MR (MVMR), adjusting for body mass index (BMI), hypertension, and coronary artery disease (CAD), respectively.ResultsIn the primary analysis, OSA was significantly associated with the increased risk of AF (OR 1.21, 95% CI 1.11–1.32) and the replicated analysis showed consistent results (OR 1.17, 95% CI 1.05–1.30). Besides, there was no heterogeneity and horizontal pleiotropy observed both in the primary and replicated analysis. Further multivariable MR suggested that the causal relationships between OSA and AF exist independently of BMI and CAD. The MVMR result after the adjustment for hypertension is similar in magnitude and direction to the univariable MR. But it did not support a causal relationship between OSA and AF.ConclusionOur study found that genetically driven OSA causally promotes AF. This causal relationship sheds new light on taking effective measures to prevent and treat OSA to reduce the risk of AF.