bluuebunny/crossref_metadata_2025_split huggingface dataset:
A copper pyramidal fractal antenna fabricated with green-laser powder bed fusion
Authors: Johnson Kerry , Burden Edward , Shaffer Michael , Noack Tobias , Mueller Matthias , Walker Jason , MacDonald Eric , Cortes Pedro , Quintana Joel 
Published: February 2022

AbstractRecent advances in additive manufacturing have enabled a new generation of electromagnetic applications to flourish. Complex geometries for dielectrics and conductors can now be simulated and rapidly fabricated from digital data. Powder bed fusion of metals is arguably the most widely adopted additive process by industry and can provide intricately-detailed structures in a wide range of high performance alloys. Copper and copper alloys have remained a challenge in this additive process, as the typical laser wavelength (approximately 1070 nm) used fails to provide sufficient absorption. Moreover, the high thermal conductivity of copper does not allow for the required heat generation for a stable melt pool. However, the recent commercial introduction of the green laser (515 nm wavelength) is enabling the printing of copper, which is particularly interesting for electrical and electromagnetic applications due to the high electrical conductivity and solderability. This paper describes the use of a green laser powder bed fusion system used to fabricate a complex fractal Sierpinski gasket ground structure with an isolated internal pyramid antenna built simultaneously—within and dielectrically isolated from the external ground element: a ship-in-the-bottle design paradigm. The electromagnetic performance, surface finish, dimensional compliance, and conductivity were measured and reported to inform the design of freestanding, geometrically-complex antennas.
U.S. Security Policy: The Dual-Use Regulation of Cryptography and its Effects on Surveillance
Authors: Riebe Thea , Kühn Philipp , Imperatori Philipp , Reuter Christian 
Published: February 2022

AbstractCryptography has become ubiquitous in communication technology and is considered a necessary part of information security. However, both the regulation to restrict access to cryptography, as well as practices to weaken or break encryption, are part of the States’ security policies. The United States (U.S.) regulate cryptography for export in international trade as a dual-use good. However, the regulation has been increasingly loosened and transferred to bilateral agreements with Information and Communication Technology companies. At the same time, the National Security Agency attempted to implement a government encryption standard to guarantee itself easier access to data, thus progressively expanding surveillance on non-U.S. citizens. In this paper, using comparative policy analysis, we examine the evolution of both security policies by tracing the historical development of U.S. regulation of cryptography as a dual-use good, and surveillance technologies, and practices used from the 1990s to today. We conclude that the impact of the dual-use regulation has affected the efficiency of surveillance technology, by loosening regulations only for mass communication services, thereby supporting the proliferation of surveillance intermediaries, while working on strategies to collaborate and exploit their coverage.
Pre- and Post-Injection Needle Pain in Patients Undergoing First Intracavernosal Injection
Authors: Baird Bryce , Wajswol Ethan , Ericson Christian , Anderson Augustus , Broderick Gregory 
Published: February 2022

ABSTRACTBackgroundIntracavernosal injections (ICI) are a well-established treatment option for men with erectile dysfunction (ED); however, the anticipation of pain with injection remains a significant barrier to the use of ICI.AimTo evaluate the patient-anticipated degree of pain versus the experienced degree of pain pre- and post-ICI in men undergoing their first injection with an erectile agent.MethodsWe studied 51 patients who underwent their first ICI in our men’s health clinic. Anticipated needle-associated pain was judged with a pre-injection score, and pain experienced during the injection was judged with a post-injection score. All patients graded their pre- and post-ICI pain using a standard 10-point scale (0–10).OutcomesPre- and post-ICI pain was defined with the visual analogue scale (0–10) in men undergoing their first penile injection.ResultsMedians and interquartile ranges (IQRs) of the patients’ age [65 years (54.5–68.0)], pre-injection pain [5 (4–7)], and post-injection pain [1 (1–2)] were recorded. Most men in the study had erectile dysfunction (68.6%) and/or Peyronie’s Disease (64.7%). The average pre-injection prediction pain score was 5.45 ± 2.15; the average post-injection perceived pain score was 1.20 ± 0.73. Thus, there was an average discrepancy of over 4 points in predicted pain vs perceived pain. A paired t-test was performed which showed a statistically significant difference between pre- and post-injection scores (P &lt; .05). A Wilcoxson Signed Rank Test showed statistical significance in the difference between pre- and post-injection pain scores (P &lt; .05).Clinical ImplicationsICI is a safe, effective treatment for patients with ED and is associated with significantly less pain than is anticipated by patients.Strengths & LimitationsThis is the first report to describe the discrepancy between pre-ICI anticipated pain and post-ICI experienced pain. Limitations include an overall small sample size.ConclusionPatients experience significantly less pain with ICI than they anticipate having. This represents an important factor to consider when counseling patients about available ED treatments.
Thermally Enhanced Water Weakening of the Solnhofen Limestone
Authors: French Melodie E. , Zhu Wenlu , Xiao Xiaohui , Evans Brian , Prior David J. 
Published: February 2022

AbstractWe report the strength and deformation behavior of Solnhofen limestone across its brittle (localized) to ductile (distributed) transition. We conducted conventional triaxial compression tests on water‐saturated and nominally dry cores of Solnhofen at temperatures up to 200°C and effective confining pressures up to 350 MPa to evaluate the roles of pore water and temperature on the deformation mechanisms of low‐porosity limestone at conditions of the upper crust. The combined effects of water and temperature on deformation and strength of the limestone are complex and reflect the concurrent operation of microfracturing, which is enhanced by both pore water and temperature, crystal plasticity, which is enhanced by temperature but not pore water, and likely also dissolution which is enhanced by water but inhibited by temperature. At ambient temperature, water causes a small reduction in the yield strength and the strength in the ductile field, but has no measurable effect of the brittle peak strength or the effective pressure of the brittle to ductile transition. At elevated temperatures, water‐saturated Solnhofen exhibits weakening in both the brittle and ductile fields up to 200 MPa effective pressure. In addition, the combined effects of pore water and temperature reduce the pressure of the brittle to ductile transition dramatically. We propose that under dry conditions temperature reduces the pressure of the brittle to ductile transition by enhancing crystal plasticity and under water‐saturated conditions enhanced microcracking is responsible. At effective pressures greater than 200 MPa, ductile deformation becomes temperature strengthening indicating the onset of dissolution mediated deformation.
Data‐Driven Method With Numerical Model: A Combining Framework for Predicting Subtropical River Plumes
Authors: Lu Wenfang , Wang Jian , Jiang Yuwu , Chen Zhaozhang , Wu Wenting , Yang Liyang , Liu Yong 
Published: February 2022

AbstractNumerical models are of fundamental usage for estuarine and coastal sciences. Although numerical simulations are widely applied, analyzing and improving them are often challenging tasks given their large volume and huge parameter space. In this study, a novel data‐driven framework is introduced to study the Minjiang River Plume (MJRP). The framework combines Self‐Organizing Map (SOM) clustering with a Hidden Markov Model (HMM). A three‐dimensional Regional Ocean Model System for MJRP is first configurated with realistic atmospheric, oceanic, and riverine forcings. By applying SOM clustering to the modeled sea surface salinity (SSS) with ∼2,000 2‐day averaged records from 2010 to 2020, we identify six major patterns of MJRP. Each pattern exhibits distinct circulation and plume structures. These MJRP patterns contain not only seasonal signals, but also rich short‐term variabilities driven by the riverine inputs and oceanic dynamics. Then, the SOM‐HMM method was applied to predict the future of the hidden state (i.e., patterns of MJRP) from the observable states (wind and river runoff). With a hypothetic SSS product from a geostationary satellite as the ground truth, we show that the SOM‐HMM method can predict MJRP patterns considerably high prediction accuracy and computational efficiency. Further, these patterns were translated back to SSS with high forecast skills. Combining a conventional numerical model with a data‐driven method, this approach can be promisingly applied in the short‐term marine forecast to support the utilization and management of other estuaries.
Rain‐Induced Stratification of the Equatorial Indian Ocean and Its Potential Feedback to the Atmosphere
Authors: Shackelford Kyle , DeMott Charlotte A. , van Leeuwen Peter Jan , Thompson Elizabeth , Hagos Samson 
Published: February 2022

AbstractSurface freshening through precipitation can act to stably stratify the upper ocean, forming a rain layer (RL). RLs inhibit subsurface vertical mixing, isolating deeper ocean layers from the atmosphere. This process has been studied using observations and idealized simulations. The present ocean modeling study builds upon this body of work by incorporating spatially resolved and realistic atmospheric forcing. Fine‐scale observations of the upper ocean collected during the Dynamics of the Madden‐Julian Oscillation field campaign are used to verify the General Ocean Turbulence Model (GOTM). Spatiotemporal characteristics of equatorial Indian Ocean RLs are then investigated by forcing a 2D array of GOTM columns with realistic and well‐resolved output from an existing regional atmospheric simulation. RL influence on the ocean‐atmosphere system is evaluated through analysis of RL‐induced modification to surface fluxes and sea surface temperature (SST). This analysis demonstrates that RLs cool the ocean surface on time scales longer than the associated precipitation event. A second simulation with identical atmospheric forcing to that in the first, but with rainfall set to zero, is performed to investigate the role of rain temperature and salinity stratification in maintaining cold SST anomalies within RLs. Approximately one third, or 0.1°C, of the SST reduction within RLs can be attributed to rain effects, while the remainder is attributed to changes in atmospheric temperature and humidity. The prolonged RL‐induced SST anomalies enhance SST gradients that have been shown to favor the initiation of atmospheric convection. These findings encourage continued research of RL feedbacks to the atmosphere.
The Fate of Sediment After a Large Earthquake
Authors: Francis Oliver , Fan Xuanmei , Hales Tristram , Hobley Daniel , Xu Qiang , Huang Runqiu 
Published: February 2022

AbstractLarge earthquakes rapidly denude hillslopes by triggering thousands of coseismic landslides. The sediment produced by these landslides is initially quickly mobilised from the landscape by an interconnected cascade of processes. This cascade can dramatically but briefly enhance local erosion rates. Hillslope and channel processes, such as landsliding and debris flows, interact to influence the total mass, caliber, and rate of sediment transport through catchments. Calculating the sediment budget of an earthquake lends insight into the nature of these interactions. Using satellite imagery derived landslide inventories, channel surveys and a literature review combined with a Monte Carlo simulation approach we present a constrained sediment budget of the first decade after the 2008 Mw7.9 Wenchuan earthquake. With this sediment budget we demonstrate that debris flows are dominant process for delivering sediment into channels and that large volumes of sediment remain in the landscape. In our study area over 88% (469.7 Mega tonnes) of the coseismically generated sediment remains on the hillslopes in 2018. Of the 12% of the sediment that was mobilised, 67% (45.2 ± 22 Mt) was mobilised by debris flows. Despite the large proportion of sediment remaining on the hillslope, the frequency of debris flows declined significantly over our observation period. The reduction in debris‐flow frequency is not correlated to reductions in the frequency of triggering storms, suggesting changes in the mechanical properties of hillslope sediment may drive this observation. The stabilization of coseismically generated sediment greatly extends its residence time and may influence catchment sediment yields for centuries or millennia.
Reduced Soil Gross N2O Emission Driven by Substrates Rather Than Denitrification Gene Abundance in Cropland Agroforestry and Monoculture
Authors: Luo Jie , Beule Lukas , Shao Guodong , Veldkamp Edzo , Corre Marife D. 
Published: February 2022

AbstractConversion of monoculture to agroforestry (integrating trees with crops) is promoted as a promising management in reducing N2O emissions from croplands. How agroforestry influences gross N2O emission (N2O + N2 from N2O reduction) and uptake (N2O reduced to N2) compared to monoculture is unknown. We used the 15N2O pool dilution technique to quantify these processes using soil cores (top 5 cm) incubated in the field with monthly measurements over two growing seasons (2018–2019) at two sites (each with paired agroforestry and monoculture) and one site with monoculture only. The unfertilized tree rows showed the lowest gross N2O emissions (P ≤ 0.002). Although tree rows occupied only 20% in agroforestry, gross N2O emissions tended to decrease by 6–36% in agroforestry (0.98–1.02 kg N2O‐N ha−1 yr−1) compared to monoculture (1.04–1.59 kg N2O‐N ha−1 yr−1). Gross N2O emissions were influenced by soil mineral N, soil respiration, and moisture content rather than by denitrification gene abundance. Soil gross N2O uptake was highest in the tree row and decreased with distance into crop rows (P = 0.012). The agroforestry tended to increase gross N2O uptake by 27–42% (0.38–0.44 kg N2O‐N ha−1 yr−1) compared to monoculture (0.30–0.31 kg N2O‐N ha−1 yr−1). In tree rows, soil gross N2O uptake correlated with nirK gene abundance which was indirectly influenced by the low mineral N‐to‐soil CO2‐C ratio. Adjusting the tree and crop areal coverages of agroforestry and optimizing fertilization can further augment the benefits of agroforestry in reducing emission and increasing uptake of N2O in soils.
Higher Levels of Soluble Reactive Phosphorus Promote Labile Organic Nitrogen Cycling in Subsurface Coastal Waters
Authors: Lu Kaijun , Gardner Wayne S. , Liu Zhanfei 
Published: February 2022

AbstractRemineralization of labile organic nitrogen is a key part of nitrogen cycling in seawater, yet factors controlling this process remain poorly understood. The degradation and fate of amino acids in coastal waters were investigated with incubation experiments using 15N‐labeled alanine (Ala). The cycling of Ala, including the release of NH4+ through remineralization, the subsequent removal of NH4+ via assimilation and nitrification, and the formation of refractory dissolved organic nitrogen (DON), was more rapid in subsurface (mid‐depth 8 m and bottom 17 m) than in surface coastal waters (2 m) of the northern Gulf of Mexico in summer. This pattern is attributed to the different levels of soluble reactive phosphorus (SRP) observed at different depths of the water column. The addition of orthophosphate to the surface water with low SRP (<0.1 μmol L−1) significantly accelerated the remineralization of amino acid, nitrification, and the formation of refractory DON. The rapid remineralization of amino acid and further nitrification in SRP‐replete waters are linked to the rapid growth of heterotrophic bacteria and ammonia‐oxidizing archaea, respectively. Taken together, these results suggest that subsurface coastal waters enriched with SRP are pre‐primed for rapid organic N metabolisms, providing mechanistic insights into nitrogen cycling in marine waters.
Investigating Effects of Solar Proton Events and Forbush Decreases on Ground‐Level Potential Gradient Recorded at Middle and Low Latitudes and Different Altitudes
Authors: Tacza J. , Odzimek A. , Tueros Cuadros E. , Raulin J.‐P. , Kubicki M. , Fernandez G. , Marun A. 
Published: February 2022

AbstractHigh‐energetic charged particles, such as solar protons, and phenomena such as Forbush decreases are eligible candidates to affect the global electric circuit. These effects have been studied by analyzing disturbances of the potential gradient in ground‐based measurements in fair weather regions. In this paper, we investigate deviations in the potential gradient diurnal curve, during solar proton events, and Forbush decreases, from the mean values obtained in fair weather conditions. In each situation, we select only events which are not accompanied or followed by the other. Using the superposed epoch analysis, in order to enhance the visualization of small effects, we study the potential gradient data recorded between January 2010 and December 2019 at two stations located at low and middle‐latitudes, and at two different altitudes: the Complejo Astronómico El Leoncito (CASLEO), Argentina: 31.78°S, 2550 m a.s.l., and the Geophysical Observatory in Świder (SWIDER), Poland: 52.12°N, 100 m a.s.l., respectively. For intense solar proton events (>100 MeV) we found a statistically significant increase of the potential gradient after solar proton events recorded at CASLEO and no such deviation in the potential gradient recorded at SWIDER. For Forbush decrease events (greater than 4%), no significant deviation of the potential gradient after the start of the event was found in both stations, however for very intense Forbush decreases (>7%) we found an increase of the potential gradient recorded at CASLEO.
Caffeine treatment started before injury reduces hypoxic–ischemic white-matter damage in neonatal rats by regulating phenotypic microglia polarization
Authors: Yang Liu , Yu Xuefei , Zhang Yajun , Liu Na , Xue Xindong , Fu Jianhua 
Published: February 2022

Abstract
Background
Reducing neuroinflammatory damage is an effective strategy for treating white-matter damage (WMD) in premature infants. Caffeine can ameliorate hypoxia–ischemia-induced brain WMD; however, its neuroprotective effect and mechanism against hypoxic–ischemic WMD remain unclear.

Methods
We used 3-day-old Sprague–Dawley rats to establish a model of cerebral hypoxia–ischemia-induced brain WMD after unilateral common carotid artery ligation and hypoxia exposure (8% O2 + 92% N2) for 2.5 h. Mechanism experiments were conducted to detect M1/M2 polarization and activation of microglia and NLRP3 inflammasome.

Results
Caffeine inhibited NLRP3 inflammasome activation, reduced microglial Iba-1 activation, inhibited microglia M1 polarization, and promoted microglia M2 polarization by downregulating CD86 and iNOS protein expression, inhibiting the transcription of the proinflammatory TNF-α and IL-1β, upregulating CD206 and Arg-1 expression, and promoting the transcription of the anti-inflammatory factors IL-10 and TGF-β. Importantly, we found that these caffeine-mediated effects could be reversed after inhibiting A2aR activity.

Conclusions
Caffeine improved long-term cognitive function in neonatal rats with hypoxic–ischemic WMD via A2aR-mediated inhibition of NLRP3 inflammasome activation, reduction of microglial activation, regulation of the phenotypic polarization of microglia and the release of inflammatory factors, and improvement of myelination development.

Impact

The direct protective effect of caffeine on hypoxic–ischemic white-matter damage (WMD) and its mechanism remains unclear. This study elucidated this mechanism using neonatal rats as an animal model of hypoxia–ischemia-induced cerebral WMD.

The findings demonstrated caffeine as a promising therapeutic tool against immature WMD to protect neonatal cognitive function.

We found that caffeine pretreatment reduced WMD in immature brains via regulation of microglial activation and polarization by adenosine A2a receptor, thereby, providing a scientific basis for future clinical application of caffeine.
Catabolic protein degradation in marine sediments confined to distinct archaea
Authors: Yin Xiuran , Zhou Guowei , Cai Mingwei , Zhu Qing-Zeng , Richter-Heitmann Tim , Aromokeye David A , Liu Yang , Nimzyk Rolf , Zheng Qingfei , Tang Xiaoyu , Elvert Marcus , Li Meng , Friedrich Michael W 
Published: February 2022

Abstract
Metagenomic analysis has facilitated prediction of a variety of carbon utilization potentials by uncultivated archaea including degradation of protein, which is a wide-spread carbon polymer in marine sediments. However, the activity of detrital catabolic protein degradation is mostly unknown for the vast majority of archaea. Here, we show actively executed protein catabolism in three archaeal phyla (uncultivated Thermoplasmata, SG8-5; Bathyarchaeota subgroup 15; Lokiarchaeota subgroup 2c) by RNA- and lipid-stable isotope probing in incubations with different marine sediments. However, highly abundant potential protein degraders Thermoprofundales (MBG-D) and Lokiarchaeota subgroup 3 were not incorporating 13C-label from protein during incubations. Nonetheless, we found that the pathway for protein utilization was present in metagenome associated genomes (MAGs) of active and inactive archaea. This finding was supported by screening extracellular peptidases in 180 archaeal MAGs, which appeared to be widespread but not correlated to organisms actively executing this process in our incubations. Thus, our results have important implications: (i) multiple low-abundant archaeal groups are actually catabolic protein degraders; (ii) the functional role of widespread extracellular peptidases is not an optimal tool to identify protein catabolism, and (iii) catabolic degradation of sedimentary protein is not a common feature of the abundant archaeal community in temperate and permanently cold marine sediments.