bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Caffeine Supplementation in a Moderate-Intensity Aerobic Exercise in Obese Asian Women
Authors: Listiarini Dian , Kushartanti Wara , Arovah Novita Intan 
Published: October 2022

While the role of exercise in managing obesity has been suggested, little is known about the effect of caffeine supplementation in the exercise program on body mass index (BMI), body fat percentage (%BF), and cholesterol. This research compared the effect of aerobic exercise with and without caffeine on BMI, %BF, and cholesterol level in obese Asian women. Twenty-seven participants were randomly allocated into three groups, which were an aerobic exercise without caffeine (A; n = 9), an aerobic exercise with 3 mg/body weight—caffeine (AC; n = 9), and a control group (C; n = 9). The exercise was a 45-min exercise training at 60%–75% maximum heart rate conducted three times weekly for 8 weeks. The mixed-method repeated-measures analysis of variance was used to assess the effect of treatments and time (i.e., pretest and posttest) on the outcome measures, followed by simple effect analyses with Bonferroni correction. While there was a significant improvement in BMI and %BF from the pretest to posttest, this was superseded by a time-by-treatment interaction effect. For the time-by-treatment interaction, the cholesterol levels in the A and AC groups were significantly lower than in C, suggesting that the benefit of the exercise program is most evident in controlling cholesterol. In conclusion, the 3 mg/kg body weight caffeine does not appear to provide additional benefit in the 8-week moderate-intensity aerobic exercise session in improving BMI, %BF, and cholesterol among obese Asian women. Further research with higher caffeine dosage and larger and more heterogenous sample sizes is recommended to confirm the findings.
Supplemental Material: Evidence for regionally continuous Early Cretaceous sinistral shear zones along the western flank of the Coast Mountains, coastal British Columbia, Canada
Authors: Wang J. , al. et 
Published: October 2022

<p>Table S1: U-Pb geochronologic analyses of unknowns. Table S2: U-Pb geochronologic analyses of primary reference materials. Table S3: U-Pb geochronologic analyses of secondary reference materials. Table S4: U-Pb geochronologic analyses of secondary reference materials from 11 different instrument-validation sessions conducted from 2019 to 2021. </p>
Oxidation of 2-Cyanothioacrylamides with Sodium Nitrite in Acidic Medium
Authors: Dahno P. G. , Zhilyaev D. M. , Dotsenko V. V. , Strelkov V. D. , Krapivin G. D. , Aksenov N. A. , Aksenova I. V. , Likhovid N. G. 
Published: October 2022

Abstract
(E)-3-Aryl-2-cyanoprop-2-entioamides, prepared by Knoevenagel condensation between aromatic aldehydes and cyanothioacetamide, react with sodium nitrite in acetic acid to form (2E,2′E)-2,2′-(1,2,4-thiadiazole-3,5-diyl)bis[3-arylacrylonitriles]. A possible mechanism and limitations of the reaction are discussed. Molecular docking was carried out in order to search for possible protein targets for the obtained 1,2,4-thiadiazoles. One of the compounds showed a pronounced antidote effect against the herbicide 2,4-D in a laboratory experiment on sunflower seedlings and under field conditions.
Impact of Different Training Modalities on Molecular Alterations in Skeletal Muscle of Patients With Heart Failure With Preserved Ejection Fraction: A Substudy of the OptimEx Trial
Authors: Winzer Ephraim B. , Augstein Antje , Schauer Antje , Mueller Stephan , Fischer-Schaepmann Tina , Goto Keita , Hommel Jennifer , van Craenenbroeck Emeline M. , Wisløff Ulrik , Pieske Burkert , Halle Martin , Linke Axel , Adams Volker 
Published: October 2022

Background:
Exercise intolerance is a cardinal feature of heart failure with preserved ejection fraction and so far exercise training (ET) is the most effective treatment. Since the improvement in exercise capacity is only weakly associated with changes in diastolic function other mechanisms, like changes in the skeletal muscle, contribute to improvement in peak oxygen consumption. The aim of the present study was to analyze molecular changes in skeletal muscle of patients with heart failure with preserved ejection fraction performing different ET modalities.

Methods:
Skeletal muscle biopsies were taken at study begin and after 3 and 12 months from patients with heart failure with preserved ejection fraction randomized either into a control group (guideline based advice for ET), a high-intensity interval training group (HIIT) or a moderate continuous training group. The first 3 months of ET were supervised in-hospital followed by 9 months home-based ET. Protein and mRNA expression of atrophy-related proteins, enzyme activities of enzymes linked to energy metabolism and satellite cells (SCs) were quantified.

Results:
Exercise capacity improved 3 months after moderate continuous exercise training and HIIT. This beneficial effect was lost after 12 months. HIIT mainly improved markers of energy metabolism and the amount and function of SC, with minor changes in markers for muscle atrophy. Only slight changes were observed after moderate continuous exercise training. The molecular changes were no longer detectable after 12 months.

Conclusions:
Despite similar improvements in exercise capacity by HIIT and moderate continuous exercise training after 3 months, only HIIT altered proteins related to energy metabolism and amount/function of SC. These effects were lost after switching from in-hospital to at-home-based ET.

Registration:

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT02078947.
Animal Welfare Issues Associated with Rearing Dairy Calves in Nepalese Context
Authors: Sah Nirvay , Kafle Krishna , Paudyal Sushil , Wasti Sanjeev , Sah Ganga K. 
Published: October 2022

Abstract
In Nepal, a predominantly Hindu country, most communities consider the cow as a sacred animal leading to their special place in society. However, male calves are neglected because of their limited utility in the context of religiously restricted beef consumption. A cross-sectional survey was conducted among the dairy farmers of the Chitwan district in the central region of Nepal to understand the rearing practices of dairy calves and the associated animal welfare concerns. A majority of the producers (70%) that participated in the survey reared female calves to be replacement dairy animals, hence providing better care and management on the farm. Male calves, however, were vulnerable to indiscriminate removal following non-humane methods; 20% of calves starved by feed withdrawal, and 20% of calves chased away from the farm to live as stray animals. Therefore, the religious, sentimental, economic, and ethical analysis of the welfare situation needs to be assessed in a broader context and a sustainable policy needs to be implemented to change the overall attitude of the farmers towards male dairy calves.
Moeder Gods, De Voedster Van Ons Leven
Authors: De Waele F. J. 
Published: October 2022

Une icône grecque de „la Nourrice de notre vie”.
Lʼauteur tâche de situer une icône grecque de la Sainte Vierge, allaitant lʼenfant Jésus, du type bien connu de la „galaktotrophousa”. La valeur de lʼexpression artistique est rehaussée par lʼinscription inconnue ailleurs: celle qui nourrit notre vie.
Lʼicône, acquise à Athènes avec lʼautorisation du Ministère des Cultes (prot. no. 105 190/3465, 1951) a peut-ètre orné une église en Anatolie avant le désastre de 1922 avant dʼavoir été emportée par un réfugié dʼAsie Mineure. De ce petit chef dʼoeuvre on peut rapprocher le poème sublime du poète grec moderne Lampros Porphyras, intitulé Les églises solitaires et qui chante avec attendrissement une de ces icônes de la Vierge, symbole de la vieille mère qui attend les siens.
Mariaʼs onbevlekte Ontvangenis in de Griekse Traditie
Authors: Sibum A.A. P.L. 
Published: October 2022

Lʼauteur esquisse à grands traits lʼévolution de la doctrine de lʼimmaculée conception dans la tradition grecque et cherche à fixer les caractères propres de cette tradition, par comparaison avec la tradition latine.
I Avant le concile dʼEphèse (431). Nous ne trouvons guère que des indices: principes féconds dont on eût pu déduire, mais dont il ne semble pas quʼon ait déduit lʼinsigne privilège de Marie.
II Depuis 431 jusquʼ à 850 environ. Lʼinfluence du concile dʼEphèse sur lʼévolution ultérieure de la doctrine est réelle, encore quʼelle ne se révèle pleinement quʼà partir du septième siècle. Dans le monde latin, les luttes engagées autour du pélagianisme ont entravé beaucoup le développement de la doctrine, et elles expliquent pourquoi les docteurs latins conçoivent lʼimmaculée conception surtout comme préservation du péché originel, par application anticipée de la passion du Sauveur. Par contre, cʼest en scrutant les exigences morales de la maternité divine, proclamée à Ephèse, que les docteurs grecs en sont arrivés — et assez rapidement une fois la question posée — à postuler pour la Théotocos une conception sans tache. Aussi la conçoivent ils de préférence comme sainteté dès lʼorigine, comme participation unique à la sainteté de Jésus. Que leur conception, sur ce point, fût plus ou moins inconsciente, cela nʼest guère probable, vu la manière dont ils envisagent, par rapport à la Vierge, certaines conséquences du péché originel, telles la mort et la concupiscence.
Een leven in dienst van de eenheidsgedachte: Mgr. Georgios Chala vazis (1881-1957)
Authors: De Waele F. J. 
Published: October 2022

Une vie au service de l’idee du rapprochement et de l’union des Eglises: mgr George Chalavazis (1881–1957).
Ayant eu le privilège pendant trente ans de connaître de pres la vie et l’oeuvre de mgr George Chalavazis, exarque des catholiques de rite Byzantin en Grèce, l’auteur tâche d’esquisser une image de cette activité prodigieuse au service de Dieu, de la religion et de la patrie. II s’honore de pouvoir rendre un hommage ému à l’auguste défunt qui après une vie saccrdotale exemplaire de plus d’un demi-siècle et une administration épiscopale de 37 ans, est décédé la veille de la fête des Taxiarques, le 7 novembre 1957. Ce grand fils des îles grecques a été la personne providentielle qui a jeté les bases d’une rénovation et d’une révalorisation des trésors de la Grèce chrétienne clans le noble aspect de sa sainte liturgie. Après un court séjour à Constantinople, il a pu rendre les plus grands services à sa patrie, qui était alors dans la plus grande détresse par suite de la catastrophe de 1922 et de l’expulsion des chrétiens anatoliens vers la mère-patrie. Entre les deux guerres mondiales il a établi à Athènes l’exarchat de rite byzantin qui, tout en professant le respect pour les frères chrétiens orthodoxes et en repoussant toute tentative de prosélytisme, a approfondi les sens religieux des meilleures traditions helléniques. L’activite surprenante durant la deuxième guerre mondiale était imprégnée d’un grand patriotisme et d’un sens profond de charité chrétienne. Dans le domaine de l’organisation catholique, la vie de l’illustre défunt marque une période de renaissance catholique en Grèce au profit de la religion et de la nation. Le grand hôpital de la Bienheureuse Mère de Dieu (Pammakaristos) n’a pas cessé de prodiguer ses bienfaits à la population si durement éprouvée par la guerre récente. Trois foyers de jeunes filles constituent un bienfait journalier pour des milliers de jeunes personnes. Les colonies de vacances accueillent les orphelins et les sinistrés, comme la grande centrale athénienne avait déjà commencé par les soins paternels aux enfants victimes du siècle troublé. Le foyer des étudiants universitaires constitue un abri et un refuge pour des centaines de jeunes intellectuels. La vie de mgr George Chalavazis a été marquée par un sens profond d’amour chrétien, a été imprégnée d’un désir ardent de travailler ensemble avec les chretiens orthodoxes à la gloire de la patrie commune, a été enfiévrée du voeu ardent du Sauveur vers le rapprochement et l’union religieuse dans le pays qui à juste titre se considère comme le berceau du christianisme européen.
Christus, Het Licht der Wereld, Gezien in de Byzantijnse Liturgie
Authors: Costanza O.S.S.J. M. 
Published: October 2022

Tous les jours l’Eglise byzantine chante le Christ Lumière du monde pendant toutes les heures de son Office divin et ses Liturgies. Même l’orientation de ses sanctuaires exprime le désir vers le Soleil de Justice. Ses Offices, le plus souvent chantés à l’aurore ou après le coucher du soleil, dramatisent la rencontre de la lumière et des ténèbres: ceux qui sont dans les ténèbres aspirent à la lumière et la Lumière inaccessible se fait accessible à ceux qui veillent.
Tous les Offices concernant les manifestations du Seigneur, c. à d. la Noël, l’Epiphanie, la Rencontre de Notre Seigneur forment une action de grâce à l’égard de la Lumière qui vient sanctifier, illuminer et même diviniser chaque homme venant au monde.
Quelques fêtes célèbrent d’une façon spéciale le Christ Lumière du monde: la fête de Pâques et surtout la Transfiguration.
Celles des Saints prouvent que ce n’est pas en vain que Notre Seigneur a illuminé le monde. Dans les textes liturgiques la Sainte Vierge est appelée Mère de la Lumière, les Saints y sont souvent nommés le reflet de la Lumière inaccessible, — et ainsi on les voit sur les icônes tout lumineux, - ils ont comme tâche de remplir toute la terre de cette lumière, tâche non seulement des Saints, mais de tout homme qui par le baptême et la confirmation est initié et „illuminé” . Ainsi il devient un rayon vivant du Soleil de Justice comme l’expriment les prières qui accompagnent le rituel de ces sacrements.
Les textes liturgiques montrent à ceux qui les étudient, que l’Eglise byzantine vit de cette Lumière divine tout en la chantant et en la transmettant.
De Oosterse Kerken te New-Delhi
Authors: van Montfoort A.A. E. 
Published: October 2022

Les églises orientales à New Delhi. Depuis le vote du 19-11-1961 presque toutes les èglises orientales sont membres du Conseil Oecuménique des Eglises. L’article donne les principaux faits et gestes de la troisième Assemblée relatifs à ces églises, ainsi que la traduction en néerlandais de quelques documents, à savoir: de la lettre de candidature de l’Eglise orthodoxe russe, de la lettre de S.S . Athenagoras et de S.B. le patriarche de Moscou, de la déclaration de l’Eglise éthiopienne et du document que toutes les églises orientales ont adressé à la section, traitant de l’unité de l’Eglise.
Les événements de New Delhi seront d’une grande importance pour l’avenir du mouvement oecuménique. Si, d’une part, la participation des églises orientales est nécessaire, on se demande de l’autre côté si, à cause de leur situation spéciale, les églises orientales des pays communistes seront à même de collaborer d’une manière efficace à la réalisation de l’unité chrétienne.
Isidoros Vankijew, Baanbreker van de Hereniging
Authors: Jacobs S.J. Hubert 
Published: October 2022

ISIDORE DE KIEV. A l’occasion du 500-me anniversaire de sa mort: 1463-27 avril-1963.
Vers 1385 Isidore de Kiev naquit e n Morée (Grèce). Il fit ses études à Constantinople où, quelque temps après, il fut nommé supérieur du couvent de S. Démétrios. Il participa au grand mouvement d’union qui caractérisait cette époque. Nommé métropolite de Kiev il représente son Eglise au concile de Ferrare-Florence et après de multiples discussions avec Marc Eugène il y signe le décret de l’union au nom du patriarcat d’Antioche et de la métropole de Kiev et de toute la Russie. Peu après le pape le nomma cardinal de la Ste Eglise Romaine. A Moscou le Grand-duc Wassilij II s’opposait fortement à la proclamation de l’union considérée comme une trahison à l’egard de l’Eglise russe. Après un séjour en prison Isidore parvint à s’enfuir à Rome. A deux reprises le pape l’envoyait à Constantinople pour y proclamer l’union de Florence, mais en vain. Ce n’est que sous Ia pression du danger imminent turc qu’en 1452 Isidore put proclamer solennellement le florentinum. Il assiste à la prise de la ville par les Turcs et faillit y laisser la vie. Il passait ses dernières années à Rome où il mourut en 1463.
Le trait caractéristique de cette vie mouvementée fut incontestablement l’amour de l’unité et un sens oecuménique peu commun à cette époque.
Made, Not Begotten: IVF and the Right to Life Under Conditions
Authors: Kummer Susanne 
Published: October 2022

In a society in which the decoupling of sexuality and human reproduction has become normal, In vitro fertilization (IVF) has mutated into a kind of standard procedure. There is little awareness of the ethical ruptures that the mechanization of human reproduction causes. The basic ethical problem with extracorporeal fertilization in a test tube is that a child is not conceived through the personal union of a man and a woman, but is “produced” in a laboratory. In the context of human creation, this entails a series of ethical problems. The technique does not merely offer another possible option for action, but it leads to a fundamental change in the attitude towards human life as such. A look at the history of assisted reproductive technology (ART) since the 1970s reveals that ethical problems, eugenic visions as well as medical experiments on humans have been inherent to the method from the very beginning. Considering that eugenic thinking has been a driving force from the very beginning it astonishes that this delicate point has hardly been recognized and highlighted so far. Robert Edwards' (1925–2013) vision went far beyond the mere treatment of infertility through the use of IVF, which he saw as enabling the selection of so-called “unhealthy life.” The article considers the risks of IVF and includes recent studies by physicians involved in reproductive medicine who are increasingly critical of their industry. Furthermore it emphasizes the core ethical question on human reproductive technology, contrasting the “ethics of procreation” with the “ethics of production.” Summary The article highlights historical aspects, considers the risks as well as the ethical questions on assisted reproductive technology.
Social connections, CEO turnover and corporate policy change
Authors: Dharmasiri Prabashi 
Published: October 2022

We examine how social connections between successive CEOs influence policy changes enacted by incoming CEOs. Using forced turnovers, we document fewer policy changes when incoming CEOs are connected to outgoing CEOs. Our results remain consistent when exposed to tests assessing endogeneity concerns such as omitted variables, selection biases and homophily concerns. We find that the reduction in policy changes is more prominent when social ties are stronger due to greater association between the individuals. Analyses further reveal that such limited policy changes enacted by connected incoming CEOs could deteriorate firm performance, highlighting the potential importance of the findings in the CEO selection process. JEL Classification: D91, J63, M12
Association of Chronic Kidney Disease and Complications Following Acute Torsional Ankle Fracture
Authors: Sinkler Margaret A. , Pennacchio Caroline A. , Kotchman Halle M. , Vallier Heather A. 
Published: October 2022

Background: Although chronic kidney disease (CKD) has been associated with poor outcomes following traumatic fractures, there is a scarcity of literature describing the effect on outcomes of ankle fractures. We will examine the impact of CKD on clinical outcomes following torsional ankle fracture, including complications and unplanned surgical procedures. Methods: A retrospective review of 1981 adult patients with torsional ankle fractures treated at a level 1 trauma center was performed to identify patients with CKD based on glomerular filtration rate. Demographic, injury, and treatment-related characteristics were collected. Outcomes included any unplanned procedure: implant removal, debridement, revision, arthrodesis, and amputation; in addition to complications of superficial infection, deep infection, and implant irritation. Patients with CKD were matched with patients without CKD by propensity score matching. Univariate comparisons between groups were conducted using chi-square and Mann-Whitney U tests. Results: 136 patients (68 with CKD and 68 without CKD) were analyzed. Of the 68 patients with CKD, the mean stage of disease was 3.7 with 24% on dialysis for a mean length of 4.1 years. Patients without CKD were more likely to undergo primary ORIF (100% vs 54%, P < .001). Thirty-five percent of patients with CKD had surgical complications vs 19% in the cohort without ( P = .07). Patients with open fractures, dislocation, and chronic kidney disease were, respectively, 5.19, 3.77, and 3.91 times more likely to have any complication ( P = .02, P = .05, P = .05). Patients with CKD were more likely to undergo unplanned arthrodesis ( P = .01). Only dislocation was an independent predictor for unplanned procedure (odds ratio = 5.08, P = .026). Conclusion: Following torsional ankle fracture, CKD is associated with increased likelihood of having a complication or an unplanned arthrodesis. Open fractures and dislocation at time of injury are also associated with complications. Our findings encourage caution about surgical treatment of ankle fractures in patients with CKD. Level of Evidence: Level III, retrospective, comparative, prognostic.
A comparative study on coagulation and hematologic laboratory techniques for blood sampling using the push-pull method from a CVC versus venipuncture
Authors: Wang Lingli , Zhang Xiaomei , Qin Yi , Wang Feng , Cui Ming , Shi Yingjuan , Chen Yu 
Published: October 2022

Objectives: To demonstrate the equivalence and substitutability of two blood collection methods: the push-pull method from a CVC and direct venous puncture (DVP). Methods: A comparative, within-subject study was conducted between September 2021 and December 2021 at a hospital in NanTong city. The sample comprised critically ill patients aged 18 and older in critical care units such as general, emergent, cardiac, respiratory, and neurological units. A total of 154 paired blood samples were collected via a CVC and direct venous puncture. This study focused on the laboratory results of the coagulation and hematologic tests. The reproducibility and reliability of the results were calculated by the mean of the coefficient of variation (CV) and the intraclass correlation coefficient (ICC). Bland–Altman statistics were used to analyze the substitutability of the two blood collection methods. Results: The difference in the means between the two methods ranged from −1.61 to 0.09, and the coefficients of variation for both methods were similar. The ICCs of the two methods were all above 0.90, which indicated excellent reliability. In the Bland–Altman plots, all of the blood samples that obtained by the push-pull method were within clinically acceptable ranges compared to the samples obtained by direct venous puncture. Conclusion: The push-pull method of collecting blood specimens from a CVC should be acceptable for coagulation and hematologic laboratory tests.