bluuebunny/crossref_metadata_2025_split huggingface dataset:
Novel intravesical therapeutics in the treatment of non-muscle invasive bladder cancer: Horizon scanning
Authors: Ward Kelly , Kitchen Mark O , Mathias Suresh-Jay , Khanim Farhat L , Bryan Richard T. 
Published: July 2022

IntroductionNon-muscle-invasive bladder cancer (NMIBC) is a common and heterogeneous disease; many patients develop recurrent or progress to muscle-invasive disease. Intravesical drug therapy is a pillar in the current management of NMIBC; notwithstanding, Mitomycin C (MMC) and Bacillus Calmette-Guérin (BCG) have numerous limitations including international supply issues, and local and systemic toxicity. Here we review novel intravesical therapeutic options and drug delivery devices with potential for clinical use in the treatment of NMIBC.MethodsPubMed, ClinicalTrials.gov and Cochrane Library searches were undertaken. Systematic reviews, meta-analyses, randomised controlled trials, single-arm clinical trials and national/international conference proceedings were included.ResultsNovel intravesical drugs, including chemotherapeutic agents, immune checkpoint inhibitors, monoclonal antibodies and gene therapies, have demonstrated varying efficacy in the treatment of NMIBC. Current evidence for the majority of treatments is mostly limited to single-arm trials in patients with recurrent NMIBC. Various novel methods of drug delivery have also been investigated, with encouraging preliminary results supporting the intravesical delivery of hyperthermic MMC and MMC hydrogel formulations.ConclusionsNovel therapeutic agents and drug delivery systems will be important in the future intravesical management of NMIBC. As our understanding of the molecular diversity of NMIBC develops, molecular subtyping will become fundamental in the personalisation of intravesical treatments. Further randomised studies are urgently required to investigate the efficacy of novel intravesical treatments and novel regimens, in comparison to current standards-of-care, particularly in the context of international BCG shortages.
Case report: Reconstruction of the left renal vein with resected autologous right renal vein interposition after excision of an inferior vena cava leiomyosarcoma
Authors: Li Xiaohang , Li Baifeng , Zhang Na , Wang Fengshan , Zhang Chengshuo , Sun Ning , Zhang Jialin 
Published: July 2022

BackgroundLeiomyosarcoma of the inferior vena cava (IVC) was a rather rare disease with the characteristics of invading the adjacent viscera. Surgical resection is the only potential curative treatment, and radiation therapy and chemotherapy for leiomyosarcoma are not definite. There is few literature reporting the leiomyosarcoma of the IVC.Case presentationA previously healthy 64-year-old female was admitted to the First Affiliated Hospital of China Medical University with the complaint of right lower quadrant abdominal pain for almost three years and worsening with a radiating ache in the waist recently. Contrast-enhanced computed tomography(CT) scans revealed a large (7.8 cm*5.5 cm*5.0 cm) irregular hypodense retroperitoneal mass with heterogeneous enhancement and invasion of the IVC, and the right ureter was compressed with proximal ureteral dilatation and hydrops. Three-dimensional CT of the IVC revealed that the IVC was encircled by the tumor with moderate invasion. During the operation, the tumor was resected en bloc with the IVC (from the suprarenal to infrarenal segment), the right kidney with ureter, and the duodenum seromuscular layer. As the left renal vein was involved, it was also partly resected. IVC reconstruction was performed with the interposition of a 20 mm diameter polytetrafluoroethylene (PTFE) prosthesis, and the right renal vein was anastomosed between the left renal vein and the reconstructed IVC to guarantee the left renal vein reflux. The patient had an uneventful recovery process with normal renal function after the operation. However, follow-up CT indicated that the left renal vein was blocked two weeks after the surgery. The patient was discharged two weeks after the operation. She continues well and has no evidence of disease fourteen months after the surgery.ConclusionsWide excision of the tumor en bloc with the IVC is the main treatment for leiomyosarcoma of the IVC. IVC reconstruction with prosthetic PTFE grafts is recommended. When the left renal vein is partly resected due to involvement of the tumor, reconstruction of left renal vein should also be performed to avoid renal impairment. If the right renal vein does not show tumor involvement, the resected right renal vein can be used to reconstruct the left renal vein.
The Quart Leap: The Invention of Soviet Ballet and Gliere's “The Red Poppy”
Authors: Королёк Богдан Алексеевич 
Published: July 2022

В статье рассматривается балет Рейнгольда Глиэра и Михаила Курилко «Красный мак» в контексте закрепившегося за ним титула «первый советский балет». История его создания анализируется в качестве мифа о чудесном обретении «подлинно советского балета». Поставленный в год десятилетия Октября, «Красный мак» завершил попытки адаптировать монархическое искусство классического танца к социалистическому строю. Авторы избрали радикально консервативный метод: антиколониальный сюжет о советских людях и классовой борьбе в Китае был развернут в музыкальных и пластических шаблонах балетного театра конца XIX века. Это дало неожиданный результат: Россия предстала на сцене колонией Советского Союза. Поэтика «Красного мака» впервые рассматривается в тесной связи с дипломатическими маневрами советского правительства и культурными событиями времени, предшествовавшего премьере. В русскоязычный контекст вводятся работы Эдварда Тайермана, крупнейшего исследователя советско-китайской культурной коммуникации 1920-х годов.
The article examines the ballet "The Red Poppy” by Reinhold Gliere and Mikhail Kurilko in the context of the title "the first Soviet ballet” that has been assigned to it and stuck. Its composition history is analyzed as a myth of the miraculous attainment of an "authentic-Soviet ballet.” Staged in the year of the decade of the October Revolution, it completed the choreographers' attempts to find a model of a "truly Soviet ballet,” that is to adapt the "monarchist art of classical dance” to the new socio-political system. The authors of "The Red Poppy” chose a radically conservative method. The anti-colonial plot about the class struggle in China and the Soviet people was developed in the patterns of the ballet theater of the late 19 century, which defined the script, the dance and the music. This gave an unexpected result of contemporary Russia appearing on the stage as a colony of the Soviet Union. For the first time the "Red Poppy” poetic is considered together with the diplomatic maneuvers of the Soviet government and the cultural events preceding the premiere. The work of Edward Thayerman, a major scholar of Soviet-Chinese cultural communication in the 1920s, is introduced into the Russian discourse.
Peer Review of Bogdan Korolyok's Article “The Quart Leap: The Invention of Soviet Ballet and Gliere's 'The Red Poppy'”
Authors: Наборщикова Светлана Витальевна 
Published: July 2022

Чтобы сделать научно -издательский процесс более прозрачным и стимулировать ведение научной дискуссии, «Музыкальная академия» публикует некоторые рецензии вместе со статьями, которым они посвящены. Светлана Наборщикова в своей рецензии на исследование Богдана Королька анализирует его подход к изучению «Красного мака» Рейнгольда Глиэра, который принято считать первым советским балетом. Отзыв Наборщиковой написан с соблюдением правил «двойного слепого» рецензирования.
To make the scientific publishing process more transparent and to stimulate scientific discussion, the Music Academy journal publishes some peer reviews along with the articles to which they are devoted. Svetlana Naborshchikova in her review on the article of Bogdan Korolyok analyzes his approach to the research of "Red Poppy” by Reinhold Gliere, which is considered to be the first Soviet ballet. Naborshchikova's review is written in compliance with the rules of "double-blind” peer review.
IMPLEMENTASI QIRAATUL KUTUB UNTUK MENINGKATKAN KELANCARAN MEMBACA KITAB KUNING DI MADRASAH DINIYAH DARUT TAQWA SENGONAGUNG PURWOSARI PASURUAN
Authors: Chusna Arifatul , Mohtarom Ali 
Published: July 2022

Qiraatul Kutub merupakan suatu proses pembelajaran membaca kitab kuning. Yang mana Qiraah sendiri berasal dari Qaraa yang berarti membaca sedangkan kutub yakni kitab. Indonesia dalam pengembangan kitab kuning, mendirikan percetakan kitab kuning dan madrasah atau lembaga-lembaga pendidikan Islam, karena kitab kuning merupakan penopang utama tradisi keilmuan Islam, tradisi keilmuan Islam dan juga sebagai penunjang dalam pendidikan Islam. “Hampir tidak diragukan lagi kitab kuning mempunyai peran besar tidak hanya dalam transmisi ilmu pengetahuan Islam, bukan hanya dikalangan komunitas santri, tetapi juga ditengah masyarakat muslim Indonesia secara keseluruhan.
Penelitian ini mengggunakan penelitian kualitatif dengan jenis penelitian penelitian lapangan (field research) yaitu suatu penelitian yang sumber datanya di lapangan. Pendekatan penelitian ini adalah pendekatan Kualitatif Deskriptif (Kualitatif lapangan). Maka dalam pengumpulan data menggunakan sumber data primer dan sekunder. Data primer dapat diperoleh didapat dari keterangan langsung oleh guru pengajar Qiraatul Kutub. Sedangkan data sekunder , didapat dari beberapa informan yang meliputi kepala madrasah, staf TU dan siswa Madrasah Diniyah Darut Taqwa serta berbagai buku atau literatur yang secara konseptual/substansial terkait dengan penelitian yang dilakukan oleh peneliti.
Implementasi Qiraatul Kutub untuk meningkatkan kelancaran kitab kuning di Madrasah Diniyah Darut taqwa sudah 15% siswa sudah lancar membaca kitab dan sudah bisa menjelaskan isi dari kitab tersebut.
ANALISIS PENERAPAN MANAJEMEN SUMBER DAYA MANUSIA BERBASIS SYARIAH DI PT BANK SYARIAH MANDIRI KCP PANDAAN KABUPATEN PASURUAN
Authors: Hilmi Hasbulloh  , Abdillah Mundir  , Wiwin Fachrudin Yusuf  
Published: July 2022

Dengan adanya penelitian ini, penulis berusaha untuk memberikan gambaran tentang Manajemen Sumber Daya Manusia (MSDM) berbasis syariah di perusahaan agar terwujud keseimbangan antara kebutuhan pegawai dengan tuntutan perusahaan. Keseimbangan tersebut merupakan kunci utama perusahaan agar dapat berkembang secara produktif.
Penelitian menggunakan metode analisis deskriptif. Analisis deskriptif yaitu suatu metode yang digunakan terhadap data yang dikumpulkan, kemudian disusun, dijelaskan dan selanjutnya di analisis. Penulis juga menggunakan metode parafrashing atau merangkum materi sedemikian rupa untuk menyempurnakan laporan ini. Selain itu, Pengumpulan data dilakukan dengan cara wawancara di Bank Syariah Mandiri KCP Pandaan.
Hasil penelitian yang telah dilakukan oleh peneliti sesuai dengan penerapan praktik Manajemen Sumber Daya Manusia (MSDM) berbasis syariah pada Bank Syariah Mandiri Kcp Pandaan Kabupaten Pasuruan mulai dari proses rekrutmen dan seleksi. Proses rekrutmen dan seleksi pada Bank Syariah Mandiri Kcp Pandaan Kabupaten Pasuruan dilakukan secara tertib. Karyawan yang memenuhi kualifikasi akan dipanggil untuk proses wawancara (interview) yang meliputi tentang pengenalan diri pelamar, motivasi, pengetahuan tentang agama, pengalaman kerja, ketrampilan khusus, karakteristik pribadi serta ujian membaca Al-Quran, dan cara menghadapi masalah serta kemampuan memecahkan berbagai masalah.
HUKUM MENIKAHI WANITA HAMIL KARENA ZINA DAN KEDUDUKAN ANAKNYA
Authors: Ali Mohtarom  
Published: July 2022

Free promiscuity between young and young people often brings things that are not desired, namely pregnancy before marriage. Pregnancy before marriage becomes a problem that requires a solution, because it brings anxiety in the community, especially parents, teachers and community leaders.
Judging from the sociological, because they feel ashamed, the parents who happen to have their daughter pregnant out of wedlock try so that if their grandchildren are born there is a father. For that they try to marry off a man, be it a man who is impregnated or not.
Therefore in this article the author will examine the opinions of the scholars and will examine the extent of the relevance of their opinions for now. Among them are, whether or not aqad of marriage is carried out in the condition of the pregnant woman, whether they may gather as befitting a husband and wife in a legal marriage, and what is the status of their children.
So that the answers obtained as follows: a marriage between a man and a woman who impregnated himself, they may have intercourse like husband and wife. And it is also legal marriage between man and woman even though not the one who impregnates, but is not allowed to have sex like husband and wife until the woman gives birth. Whereas the status of his son only breathed to the mother not to the father (the man who impregnated him).
Program Aplikasi Sederhana Kas Masuk Dan Kas Keluar Berbasis Visual Basic 2010 (Studi Kasus Cv Trigi Rama Mandiri)
Authors: Muhtar Widia , Indaryono Indaryono , Priatna Apit 
Published: July 2022

Semakin pesatnya perkembangan sistem informasi mendorong instansi swata dan instansi pemerintahan menerapkan sistem informasi. Dengan berbagai macam sistem informasi yang memungkinkan memproses data dan laporan lebih cepat. Hal tersebut tidak diikuti oleh CV Trigi Rama Mandiri, dalam memproses dan membuat laporan masih menggunakan sisten manual. Dalam proses data dan laporan dengan sistem manual membutuhkan waktu yang cukup lebih lama. Dalam menghitung kas masuk dan kas keluar hanya menggunakan kalkulator yang terkadang harus dihitung berkali-kali karena adanya kesalahan memasukan data. Dalam menghitung kas masuk dan kas keluar sehingga dibutuhkan sebuah sistem agar berjalan dengan efektif dan efisien. Penulisan ini bertujuan untuk menghasilkan sebuah program aplikasi yang bisa digunakan dalam laporan kas masuk dan kas keluar. Metode yang digunakan dalam penulisan ini adalah Design Design Science Research Methode (DSRM). Hasil penelian berupa program aplikasi kas masuk dan kas keluar dengan basis Visual Studio 2010 dengan Database menggunakan SQL Server.
Hubungan Antara Minat Baca Terhadap Hasil Belajar Ekonomi Siswa SMK Mardi Bakti Jakarta
Authors: Haryani Windi , Narsih Dwi , Saripah Saripah 
Published: July 2022

The purpose of this study was to determine the relationship between reading interest on Economics learning outcomes at SMK Mardi Bakti Jakarta. The author uses a korelational quantitative method. Population of this research is all of X AK student which are 34 student. The sampling technique used in this research is nonprobability sampling which is saturated sample, so the sample in this reseach are 34 student The variables of this study consisted of two variables, namely variable (X) Interest in Reading and Variable (Y) namely Learning Outcomes. The data analysis techniques carried out by the t-test formula at a significant level of 0.05. The results of this study indicate that tcount =1.11< t table =2.037, it is concluded that there is no relationship between reading interest on student Economic learning outcomes at SMK Mardi Bakti Jakarta.
Pengaruh Relationship Marketing dan Kepuasan Pelanggan Terhadap Loyalitas Pelanggan Pada Toko BEST Pematangsiantar
Authors: Siregar Robert Tua , Sofiyan Sofiyan , Siahaan Yansen , Loist Christine , Olympic Olympic 
Published: July 2022

Objective. The purpose of this study was to determine: To analyze the effect of relationship marketing on customer satisfaction at the Best Pematangsiantar Store. Then the influence of customer satisfaction on customer loyalty at the Best Pematangsiantar Store.
Research Methods. The object of research is Pematangsiantar Best Store which is located on Jl. Sutomo No. 63, Kelurahan Dwikora, Kecamatan Siantar Barat, Pematangsiantar, 21118. In this study, all members of the population were used as data sources, namely as the sample of the researcher. Where the research population is the Best Pematangsiantar Store customers with a total of 35 people, who also become the research sample.
Results. The results of simple linear regression analysis show that relationship marketing has a positive effect on customer satisfaction and customer satisfaction has a positive effect on customer loyalty. The results of simple linear regression analysis show that relationship marketing has a strong and positive relationship with customer satisfaction, and customer satisfaction has a very strong and positive relationship with customer loyalty.. The results of the hypothesis test state that H0 is rejected, meaning that relationship marketing has a positive and significant effect on customer satisfaction, and customer satisfaction has a positive and significant effect on customer loyalty.
Conclusion. Relationship marketing at the Best Pematangsiantar Store in this case has been categorized as good. Even though it has been categorized as good, the leadership should try to improve and also create long-term relationships with customers and also fulfill all the needs according to the wishes of these customers. Customer satisfaction at the Best Pematangsiantar Store in this case has been categorized as good. Even though it has been categorized as good, it is better for the leadership to maintain long-term relationships and give good attention so that customers will feel more satisfied. Customer loyalty at the Best Pematangsiantar Store in this case has been categorized as good. Even though it has been categorized as good, the leadership should try to establish close relationships with customers and pay attention so that customers become loyal.
Pengaruh Beban Pajak Tangguhan Terhadap Praktik Perataan Laba Pada Perusahaan Batu Bara Di BEI
Authors: Kasman Hendra Kasman 
Published: July 2022

Perataan laba tindakan yang menguntungkan suatu pihak tertentu dalam penyajian atas pendapatan perusahaan yang begitu tinggi, dengan mengalihkan pendapatan menjadi stabil dengan memodifikasi suatu tindakan kecurangan yang dilakukan perusahaan, agent akan melakukan suatu kewajiban dalam melindungi perusahaan dari dampak yang tidak baik untuk masa depan perusahaan. Dikarenakan kinerja manajer tidak dapat menyakinkan pihak yang ingin menanamkan modal kedalam perusahaan disini dimaksud investor. Beban pajak tangguhan beban yang harus dikeluarkan oleh perusahaan dalam periode akuntansi yang dikarenakan dalam kegiatan bisnis perusahaan yang mendapatkan laba yang tinggi maka beban yang dikeluarkan perusahaan akan semangkin tinggi. Hasil penelitian ini adalah beban pajak tangguhan tidak berpengaruh terhadap praktik perataan laba
Pengaruh Kualitas Pelayanan dan Fasilitas Kesehatan Terhadap Kepuasan Pasien BPJS Pada RSU Mina Padi Kabupaten Simalungun
Authors: Efendi Efendi , Butarbutar Marisi , Putra Loist Abdi , Silaen Musa Fernando , Yolandra Arrum Yolandra 
Published: July 2022

Objective. The purposes of this research are: 1) To describe the quality of service, health facilities and satisfaction of BPJS patients at Mina Padi General Hospital, Simalungun Regency. 2) To determine the effect of service quality and health facilities on BPJS patient satisfaction at Mina Padi General Hospital, Simalungun Regency, either simultaneously or partially.
Research Methods. The research design used in this research is library research and field research. Data collection techniques used in this research are questionnaire method, interview method and documentation method.
Results. The results of the study can be concluded as follows: Service quality, health facilities are good, and patient satisfaction is also categorized as good. The results of the regression analysis are = 7.407 + 0.378 X1 + 0.364 X2, meaning that the quality of services and health facilities has a positive and significant effect on patient satisfaction. 3) The results of the correlation analysis obtained a value of r = 0.794, meaning that there is a strong and positive relationship between the quality of services and health facilities and patient satisfaction. The value of the coefficient of determination R = 0.631 means that the level of patient satisfaction can be explained by the quality of services and health facilities of 63.1%. The research hypothesis H0 is rejected, meaning that the quality of services and health facilities has a positive and significant effect on BPJS patient satisfaction at Mina Hospital in Simalungun Regency, either simultaneously or partially.
Conclusion. To create a good quality of service, Mina Padi General Hospital in Simalungun Regency should increase the number of inpatient rooms so that sick patients can be treated immediately and receive incentive treatment from medical personnel. To improve health facilities at Mina Padi General Hospital, Simalungun Regency, it is better to increase the number of specialist doctors so that patients who need treatment can be handled immediately. And so that patients feel comfortable, the hospital should be able to overcome the smell of waste. To create patient satisfaction, it is recommended that Mina Padi Hospital, Simalungun Regency, need to increase the supply of medicines needed by BPJS patients.
ON THE SPECIFICS OF THE USE OF BACCHIC VOCABULARY IN D. S. ME REZHKOVSKY’S TRILOGY “CHRIST AND THE ANTICHRIST” (ON THE EXAMPLE OF THE NOVEL “THE DEATH OF THE GODS. JULIAN THE APOSTATE”)
Authors: Димитриева Ольга Альбертовна 
Published: July 2022

В статье рассматривается специфика употребления вакхической лексики, в частности, определяется коннотативное наполнение лексемы «вино». Актуальность работы обусловлена ее вхождением в круг исследований, связанных с изучением авторского идиостиля, а также с определением оценочных свойств ситуации винопития в романе. Новизна исследования видится в том, что анализируются индивидуальные особенности автора в интерпретации ситуации винопития. Цель работы - выделить особенности индивидуально-авторской репрезентации семантического фрагмента винопитие и определить языковые средства его воплощения в романе Д. С. Мережковского «Смерть богов. Юлиан Отступник». Основным методом исследования является метод семантического и лингвостилистического анализа. Выявлено, что в романе «Смерть богов. Юлиан Отступник» слово «вино» обладает в основном положительной коннотацией. Отмечается, что «вино» включается в ряд слов, эстетизирующих процесс винопития, что влечет за собой выделение дополнительных его характеристик. Определяется роль частносубъективной оценки, которая преобладает над общей оценкой. При анализе компаративных тропов, включающих слово «вино», показано, что оно сравнивается как с хорошей поэзией, так и с высокими чувствами человека (любовью) и Божьим наказанием. Вино выполняет сакральную функцию: вовлекается в языческие ритуалы.
The article discusses the specifics of the use of Bacchic vocabulary, in particular, the connotative content of the lexeme wine is determined. The relevance of the paper is due to the study of the author’s idiostyle, as well as the determination of the evaluative properties of the wine drinking situation in the novel. The author sees the novelty of the study in the fact that individual characteristics are analyzed in the interpretation of the situation of wine drinking. The purpose of the study is to highlight the peculiarities of the individual author’s representation of the semantic fragment of wine drinking and to determine the linguistic means of its embodiment in the novel by D. S. Merezhkovsky “The Death of the Gods. Julian the Apostate”. The main method of research is the method of semantic and linguistic and stylistic analysis. It is revealed that in the novel “Death of the Gods. Julian the Apostate” the word wine mostly has a positive connotation. It is noted that wine is included in a number of words that aestheticize the process of wine drinking, which entails the allocation of its additional characteristics. The role of the individual subjective assessment, which prevails over the general assessment, is determined. When analyzing comparative tropes involving the word wine, it is shown that it is compared both with good poetry and with high human feelings (love) and God’s punishment. Wine performs a sacred function: it is involved in pagan rituals.