bluuebunny/crossref_metadata_2025_split huggingface dataset:
Extraction of pyridine using systems based on water-soluble polymers
Authors: Solovev V O , Soloveva S V , Milevsky N A 
Published: January 2022

Abstract
In the process of using hydrocarbon fractions containing a large amount of nitrogenous compounds, nitrogen oxides are released into the atmospheric air, which have a negative impact on the environment and human health. The traditional cleaning method is treatment with a 25% sulfuric acid solution and subsequent hydrotreating. However, this process becomes disadvantageous due to its inability to achieve ultra-low concentrations of nitrogen-containing compounds (<10 ppm). Extraction using non-toxic and environmentally friendly water-soluble polymers is a promising alternative compared to traditional methods. This work presents the dependence of the interphase distribution of pyridine on the composition of extraction systems based on water-soluble polymers. According to the results of the study, it was found that polyethylene glycol-400, polypropylene glycol-425 and methyl ether of polyethylene glycol-350 exhibit effective extraction properties in relation to pyridine and extract it by 90.95%, 90.33% and 87.82% in one extraction stage, respectively. It was also found that the use of two-phase aqueous systems based on water-soluble polymers in the process of extracting pyridine is promising.
Study of caffeine and coumarin extraction kinetics in an aqueous two-phase system based on polyethylene glycol 1500
Authors: Zinov’eva I V 
Published: January 2022

Abstract
Caffeine and coumarin are organic compounds of plant origin, which have biological activity and have found wide application in medicine, pharmaceutical, perfumery and food industries. Recovery of caffeine and coumarin from aqueous solutions using liquid-liquid extraction is the most effective method. In the present work the kinetic dependences of caffeine and coumarin in the aqueous two-phase system (ATPS) of PEG 1500 - Na2SO4 - H2O were experimentally obtained. It was established that equilibrium in the system is achieved after 17 minutes for caffeine and after 12 minutes for coumarin. The effect of ultrasound on the extraction rate of caffeine and coumarin in an aqueous two-phase system was also studied.
Membranes adsorber from oil palm empty fruit branches (OPEFB): preparation and fabrication
Authors: Hidayah N , Darsono P D , Elma’ M , Mahmud  , Syauqiah I , Akbar H R , Amenia A , Putra D G L , Huda N , Rahma A 
Published: January 2022

AbstractOil Palm empty fruit branches (OPEFB) are solid waste that are numerous produced from palm oil mills. OPEFB is economically and potentially used as membrane adsorber material due to has good thermal stability, chemical resistance and biodegradability. The objectives of this work is to preparate and fabricate the OPEFB membrane adsorber which is activated by physical activation. The OPEFB has been cleaned and dried, subsequently heated at 500 °C for 30 min via pyrolysis. The activated OPEFB was sieved using 200-400 mesh and followed by the addition of 2-propanol, NH4Cl, polyvinyl alcohol (PVA) and polyethylene glycol (PEG) to become a mixture. The activated OPEFB ratio were varied in the mixtures to obtain the best composition in order to produce a good membrane adsorber texture for casting. FTIR shows on wavenumber at 1082 cm−1indicates that there is O-H stretching functional groups and bands at 943 cm−1correspons to C=O functional group. It is concluded that the membrane mixtures can be employed as membrane adsorber due to carbon content which creates strong matrix applied for gas separation.
The use of olive waste for development sustainable rigid pavement concrete material
Authors: Dahim M A , Abuaddous M , Al-Mattarneh H , Alluqmani A E , Ismail R 
Published: January 2022

Abstract
Recycle and reuse of agriculture and industrial wastes becomes a big chalenge in different parts of the world. The success in the waste recycle could lead to conserve the environment, reduce the use of cement, and improve health environment. This paper presents the potential use of fly ash from olive oil waste in Jordan to improve concrete material which could be used as a sustainable material for rigid pavement and building construction material. Olive oil ash was collected from olive oil mill and replace cement in producing concrete material. The range of cement replacement was 0% to 12.5% with increment 2.5%. The results indicate that olive oil reduces the workability of concrete material. The reduction of the slump of concrete increases with increasing olive ash content. Strength and durability of concrete improved and increased with increasing olive ash content in concrete up to 7.5 percent then the strength reduced. The results in this study show that the use of 7.5% was the optimum replacement of cement. This percent could produce concrete with higher strength and higher durability in comparison with the control concrete mix. Olive waste ash enhances both strength and durability because it reduces the effective water-cement ratio in concrete mix and filling the pore and void structure in concrete material. The benefits of this study could reduce the cost of concrete and recycle waste material and enhance concrete properties.
The flexural strength of glue laminated timber beams based on deflection and strain rate with four point bending loading system
Authors: Maricar S , Sulendra K , Listiawaty H , Baide H O 
Published: January 2022

Abstract
The development of utilization of low quality wood as construction material is needed to reduce the exploitation of natural forests. However, low quality wood species have disadvantages in terms of mechanical properties. The mechanical properties of Sengon wood are relatively low, so it does not qualify as a structural element. Therefore, the system glulam can be applied to overcome this problem. The system glulam can produce relatively light structural elements with adequate performance. This system has been extensively developed, even at the stage of applying external reinforcement, to improve the performance of structural laminated beams. On that basis, this study aims to determine the flexural strength of laminated beams of Sengon wood as a low quality wood species. In order to achieve this goal, the laminated beam was tested using method four point bending test method. Tests were carried out on long span laminated beams (L = 2750 mm) to observe flexural strength. There are five (5) laminated blocks tested, namely (BLS-1, BLS-2, BLS-3, BLS-4 and BLS-5). Each group has dimensions of 55 mm in width and 155 mm in height. Each specimen consists of six layers of wood boards with a density Falcata 0.3 g / cm3. The thickness of each layer was 26 mm and bonded with resin urea formaldehyde cold setting. Double-sided adhesive laying of 350 gr / m2 at a compressive force of 2 MPa. The analysis result shows that the load-deflection relationship between BS-L consists of linear and nonlinear phases. The load performance characteristics of the two types of laminated beams are expressed as the ratio of the proportional limit load to the maximum load. The ratio value is expressed in the form P
eBL-s = 0.7P
max BL-S andM
eBL-s = 0.7M
max BL-S. This form is similar to previous studies with a Pe to Pmax ratio of 0.80.9. In this case, the average flexural strength of the laminated beam is 17 MPa with a maximum strain of 0.004.
Shear strength behaviour of liquefiable sand of petobo on treated by agarose under direct shear test
Authors: Beddu A , Setiawan H , Nuraida  , Anugrah M R 
Published: January 2022

Abstract
Liquefaction process is associated with the loss of the shear strength of the saturated loose sands caused by strong earthquakes. Due to mitigitation of liquefaction hazard, an appropriate mitigation of liquefaction using environmentally friendly methods is critical and becoming increasingly important and unavoidable. The laboratory investigation was carried out to study the shear strength behaviour of liquefiable sand of Petobo treated by agarose on different concentration 1%,3% 5%. A series of direct shear test were conducted under three level of vertical stress 10 kPa, 20 kPa, and 30 kPa on the specimen. It was found that the optimum content of agarose which can be considered is at 1%-3%, using stress ratio (τ/σv) analysis shows that stress ratio decreases with increasing the vertical stress on the same agar content. The implication this result that the application of this method must consider variation of material source and characteristic, and the suitable level of vertical stresses.
Determination of earthquake prone zones at university of tadulako based on dominant periods and peak ground acceleration (PGA)
Authors: Meidji I U , Mulyati S , Janat N R , Jayadi H , Asrafil  
Published: January 2022

Abstract
University of Tadulako is the largest State University in Palu City. When an earthquake with a magnitude of 7.4 Mw on September 28, 2018, occurred, many buildings were damaged and even collapsed at that time, even causing casualties due to the rubble. Research on the Local Site Effect is essential for the assessment of seismic hazard. In this study, the local site effect was analyzed using the HVSR method based on microtremor data. The predominant Period (To) ranges between 1.709 s to 3.816 s, indicates that this area consists of alluvium and has a very thick sediment layer. Another parameter calculated in this paper is the peak ground acceleration (PGA) with values from 0.914 g to 0.924 g. This value is the first indicated soil damage level due to ground motions. The results of this study can be used as a consideration in the development of regional spatial planning and building structures based on earthquake analysis.
Potential of tidal power plants on Tibo Beach with spektrum method
Authors: Setiyawan  , Rusdin A , Amaliah T , Olphino  
Published: January 2022

Abstract
As time evolved, the demand for electrical energy also increased. As a result, renewable energy is needed to replace fossil fuels as fuel for electricity generation. Tidal water is one of the renewable alternative energy sources used as fuel for electricity generation. The tides will never run out and can also be predicted. One method that can predict data about waves is the Spectrum Method. Tide prediction data can be indicated by carrying out tidal height observations for 15 days at Tibo Beach, Donggala Regency, Central Sulawesi. Based on observations, the data obtained are the highest high water level (HHWL) is 2.4 meters, and the lowest low water level (LLWL) is 0.1 meters. Also, the type of tides on the Tibo coast is a type of mixed waves that tend to double daily, there are two tides with high water and two tides with low water with different water levels. Because the value of formzahl is 0.312. With a 2.4 meter high HHWL and a sea area of 35.4 km2, the electricity generated is 13.08 MW.
Smart water meter for automatic meter reading
Authors: Amir A , Fauzi R , Arifin Y 
Published: January 2022

Abstract
Clean water is one of the main sectors in smart city that need well management. One of the clean water management is utilization of water meters. The smart meter is more suitable applied for smart city. Recent Smart Water Meter allows water authorities to obtain water consumption data remotely. It also provides ability to collect and record the data in real time that can be utilised for multipurpose. However, in Indonesia, the water meters are used only to measure the total volume of clean water consumption for billing purpose only using mechanical water meter and requires labour intensive manual. Currently, many researches on smart meter design have been developed. However, the smart meter only measure and record the water consumption, without ability in which customer can determine the amount of water as needed. This paper describes design and development of smart water metering with Internet of Things. Flow meter is used as a sensor of water flowing through the pipe. The ability of the proposed smart meter is not only to measure and to record the volume water consumed, but also the customer can determine the water desired and required. The volume of water measured by the smart meter is compared with the manual measurement. The result shows that the water measured manually differs slightly from smart meter measurement using water flow sensor. The maximum difference, error, is 0.03 litres. The proposed smart meter has ability to close the main valve once the determined amount of water is reached.
Photoacoustic imaging of 3D-printed vascular networks
Authors: Ma Chenshuo , Li Wanlu , Li Daiwei , Chen Maomao , Wang Mian , Jiang Laiming , Mille Luis Santiago , Garciamendez Carlos Ezio , Zhao Zhibo , Zhou Qifa , Zhang Yu Shrike , Yao Junjie 
Published: January 2022

Abstract
Thrombosis in the circulation system can lead to major myocardial infarction and cardiovascular deaths. Understanding thrombosis formation is necessary for developing safe and effective treatments. In this work, using digital light processing (DLP)-based 3D printing, we fabricated sophisticated in vitro models of blood vessels with internal microchannels that can be used for thrombosis studies. In this regard, photoacoustic microscopy (PAM) offers a unique advantage for label-free visualization of the 3D-printed vessel models, with large penetration depth and functional sensitivity. We compared the imaging performances of two PAM implementations: optical-resolution PAM and acoustic-resolution PAM, and investigated 3D-printed vessel structures with different patterns of microchannels. Our results show that PAM can provide clear microchannel structures at depths up to 3.6 mm. We further quantified the blood oxygenation in the 3D-printed vascular models, showing that thrombi had lower oxygenation than the normal blood. We expect that PAM can find broad applications in 3D printing and bioprinting for in vitro studies of various vascular and other diseases.
Plastic deformation behavior and constitutive modeling of Cu-50Ta alloy during hot compression
Authors: Pu Bo , Song Ping , Li Wen-Bin , Yao Wen-Jin , Wang Xiao-Ming 
Published: January 2022

Abstract
This paper presents a study on plastic deformation behavior of Cu–50Ta alloy at temperatures of 286–473 K and strain-rate of 0.01–6200 s−1. The effects of temperature, strain-rate, and strain on the yield strength, flow stress, and strain-rate sensitivity coefficient were determined. A phenomenological model was established to predict variation of the strain-rate sensitivity coefficient for Cu–50Ta alloy under dynamic compression. A Johnson–Cook constitutive model was established to predict the equivalent stress–equivalent plastic strain relationship under extreme deformation (high temperature and strain-rate). The results showed that the plastic deformation behavior of Cu–50Ta alloy was affected by temperature, strain-rate, and strain. The material exhibited obvious strain-rate strengthening and thermal softening. As the strain-rate increased, the yield strength logarithmically increased. At a temperature of 286 K, the strain-rate increased from 0.01 s−1 to 6200 s−1, and the yield strength increased from 543.75 MPa to 881.13 MPa. In addition, the yield strength linearly decreased as the deformation temperature increased. Under conditions of dynamic deformation, the variation of strain-rate sensitivity coefficient could be expressed as a function of strain-rate and strain. The phenomenological model accurately described the variation of the strain-rate sensitivity coefficient of Cu–50Ta under dynamic deformation conditions. The Johnson–Cook constitutive parameters, calibrated by experimental data, described the plastic deformation behavior of the alloy under high-velocity impact.
Physical processes behind interactions of microplastic particles with natural ice
Authors: Chubarenko Irina 
Published: January 2022

Abstract
Microplastic particles (MPs, <5 mm) are found in marine ice in larger quantities than in seawater, however, the distribution pattern within the ice cores is not consistent. To get insights into the most general physical processes behind interactions of ice and plastic particles in cool natural environments, information from academic and applied research is integrated and verified against available field observations. Non-polar molecules of common-market plastics are hydrophobic, so MPs are weak ice nucleators, are repelled from water and ice, and concentrate within air bubbles and brine channels. A large difference in thermal properties of ice and plastics favours the concentration of MPs at the ice surface during freeze/thaw cycles. Under low environmental temperatures, falling in polar regions below the glass / brittle-ductile transition temperatures of the common-use plastics, they become brittle. This might partially explain the absence of floating macroplastics in polar waters. Freshwater freezes at a temperature well below that of its maximum density, so the water column is stably stratified, and MPs eventually concentrate at the ice surface and in air bubbles. In contrast, below growing sea ice, mechanisms of suspension freezing under conditions of (thermal plus haline) convection should permanently entangle MPs into ice. During further sea ice growth and aging, MPs are repelled from water and ice into air bubbles, brine channels, and to the upper/lower boundaries of the ice column. Sea ice permeability, especially while melting periods, can re-distribute sub-millimeter MPs through the brine channels, thus potentially introducing the variability of contamination with time. In accord with field observations, analysis reveals several competing factors that influence the distribution of MPs in sea ice. A thorough sampling of the upper ice surface, prevention of brine leakage while sampling and handling, considering the ice structure while segmenting the ice core—these steps may be advantageous for further understanding the pattern of plastic contamination in natural ice.
Biclique extension as an effective approach to identify missing links in metabolic compound–protein interaction networks
Authors: Thieme Sandra , Walther Dirk 
Published: January 2022

AbstractMotivationMetabolic networks are complex systems of chemical reactions proceeding via physical interactions between metabolites and proteins. We aimed to predict previously unknown compound–protein interactions (CPI) in metabolic networks by applying biclique extension, a network-structure-based prediction method.ResultsWe developed a workflow, named BiPredict, to predict CPIs based on biclique extension and applied it to Escherichia coli and human using their respective known CPI networks as input. Depending on the chosen biclique size and using a STITCH-derived E.coli CPI network as input, a sensitivity of 39% and an associated precision of 59% was reached. For the larger human STITCH network, a sensitivity of 78% with a false-positive rate of &lt;5% and precision of 75% was obtained. High performance was also achieved when using KEGG metabolic-reaction networks as input. Prediction performance significantly exceeded that of randomized controls and compared favorably to state-of-the-art deep-learning methods. Regarding metabolic process involvement, TCA-cycle and ribosomal processes were found enriched among predicted interactions. BiPredict can be used for network curation, may help increase the efficiency of experimental testing of CPIs, and can readily be applied to other species.Availability and implementationBiPredict and related datasets are available at https://github.com/SandraThieme/BiPredict.Supplementary informationSupplementary data are available at Bioinformatics Advances online.
M&Ms: a versatile software for building microbial mock communities
Authors: García-García Natalia , Tamames Javier , Puente-Sánchez Fernando 
Published: January 2022

Abstract

Summary
Advances in sequencing technologies have triggered the development of many bioinformatic tools aimed to analyze 16S rDNA sequencing data. As these tools need to be tested, it is important to simulate datasets that resemble samples from different environments. Here, we introduce M&Ms, a user-friendly open-source bioinformatic tool to produce different 16S rDNA datasets from reference sequences, based on pragmatic ecological parameters. It creates sequence libraries for ‘in silico’ microbial communities with user-controlled richness, evenness, microdiversity and source environment. M&Ms allows the user to generate simple to complex read datasets based on real parameters that can be used in developing bioinformatic software or in benchmarking current tools.

Availability and implementation
The source code of M&Ms is freely available at https://github.com/ggnatalia/MMs (GPL-3.0 License).

Supplementary information
Supplementary data are available at Bioinformatics online.
The human cognition-enhancing CORD7 mutation increases active zone number and synaptic release
Authors: Paul Mila M , Dannhäuser Sven , Morris Lydia , Mrestani Achmed , Hübsch Martha , Gehring Jennifer , Hatzopoulos Georgios N , Pauli Martin , Auger Genevieve M , Bornschein Grit , Scholz Nicole , Ljaschenko Dmitrij , Müller Martin , Sauer Markus , Schmidt Hartmut , Kittel Robert J , DiAntonio Aaron , Vakonakis Ioannis , Heckmann Manfred , Langenhan Tobias 
Published: January 2022

Abstract
Humans carrying the CORD7 (cone-rod dystrophy 7) mutation possess increased verbal IQ and working memory. This autosomal dominant syndrome is caused by the single-amino acid R844H exchange (human numbering) located in the 310 helix of the C2A domain of RIMS1/RIM1 (Rab3-interacting molecule 1). RIM is an evolutionarily conserved multi-domain protein and essential component of presynaptic active zones, which is centrally involved in fast, Ca2+-triggered neurotransmitter release. How the CORD7 mutation affects synaptic function has remained unclear thus far.
Here, we established Drosophila melanogaster as a disease model for clarifying the effects of the CORD7 mutation on RIM function and synaptic vesicle release. To this end, using protein expression and X-ray crystallography, we solved the molecular structure of the Drosophila C2A domain at 1.92 Å resolution and by comparison to its mammalian homologue ascertained that the location of the CORD7 mutation is structurally conserved in fly RIM. Further, CRISPR/Cas9-assisted genomic engineering was employed for the generation of rim alleles encoding the R915H CORD7 exchange or R915E, R916E substitutions (fly numbering) to effect local charge reversal at the 310 helix. Through electrophysiological characterization by two-electrode voltage clamp and focal recordings we determined that the CORD7 mutation exerts a semi-dominant rather than a dominant effect on synaptic transmission resulting in faster, more efficient synaptic release and increased size of the readily releasable pool but decreased sensitivity for the fast calcium chelator BAPTA. In addition, the rim CORD7 allele increased the number of presynaptic active zones but left their nanoscopic organization unperturbed as revealed by super-resolution microscopy of the presynaptic scaffold protein Bruchpilot/ELKS/CAST.
We conclude that the CORD7 mutation leads to tighter release coupling, an increased readily releasable pool size and more release sites thereby promoting more efficient synaptic transmitter release. These results strongly suggest that similar mechanisms may underlie the CORD7 disease phenotype in patients and that enhanced synaptic transmission may contribute to their increased cognitive abilities.