bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychiatric diagnostic dilemmas among people with intellectual and developmental disabilities
Authors: Charlot L. R. , Hodge S. M. , Holland A. L. , Frazier J. A. 
Published: August 2022

AbstractBackgroundResearch regarding the accuracy of co‐morbid psychiatric diagnoses in individuals with intellectual and developmental disabilities (IDD) is sparse. Yet correct diagnostic assignment is vital so that effective and appropriate treatment can be implemented, especially for the large numbers of individuals requiring expensive and restrictive behavioural health crisis services.MethodA retrospective review of de‐identified data from multidisciplinary specialty team assessments completed for 50 individuals with ID (IntellectualDisability) with and without ASD and unresolved behavioural health challenges was conducted. The accuracy and reliability of the psychiatric diagnoses upon referral were compared with the diagnoses after the comprehensive team evaluation, and within‐individual diagnostic agreement was calculated. The agreement between the Mood and Anxiety Semi‐Structured interview tool (MASS) and the full team evaluation was also calculated. The influence of demographic and clinical characteristics on diagnostic agreement was explored.ResultsThe most common chief complaints upon referral were aggression to others and self‐injurious behaviour. Individuals were taking a median of six medications (interquartile range: 5 to 7); 80% were taking an antipsychotic medication. The most common medical conditions were constipation (70%) and gastroesophageal reflux disease (52%). Measures of interrater reliability of the referral diagnoses with the team assessment were below 0.5 (kappa range: −0.04 to 0.39), with the exception of ruling out dementia (kappa = 0.85). The interrater reliability estimates for the MASS evaluations for depression and anxiety were higher (kappa = 0.69 and 0.64) and reflected higher sensitivity and PPV. The odds of any referral diagnosis being confirmed by team evaluation were low: 0.25 (range: 0 to 0.67). The level of diagnostic agreement for each patient was not significantly attributable to demographic or clinical characteristics, although effect sizes indicate a possible positive relationship to age and the number of prescribed psychotropic medications at referral.ConclusionIndividuals in the current study had serious psychiatric and behavioural problems despite psychiatric care in their communities. The majority of psychiatric diagnoses provided upon referral were not supported by the multidisciplinary specialty team's assessment. In addition to possible diagnostic inaccuracy, the group in the study suffered from multiple medical co‐morbidities and were exposed to polypharmacy. Results emphasise the importance of multidisciplinary evaluation by clinicians with expertise in neurodevelopmental disabilities when people with ID with and without ASD have complex behavioural health needs that are unresponsive to usual care. In addition, based on agreement with the full team evaluation, the MASS shows promise as an assessment tool, especially with regards to identifying anxiety and depression.
Topical cetirizine for treating androgenetic alopecia: A systematic review
Authors: Chen Xiaomei , Xiang Hongmei , Yang Ming 
Published: August 2022

AbstractBackgroundCetirizine, a widely used agent for allergic disorders, has recently been topically used for treating androgenetic alopecia (AGA). We aimed to summarize the current evidence regarding the effectiveness and safety of topical cetirizine for treating AGA.MethodsWe searched Ovid MEDLINE, Embase, and Cochrane Central Register of Controlled Trials. We included both randomized controlled trials (RCTs) and non‐randomized clinical trials.FindingsWe initially identified 102 records, of which, we included two RCTs and one non‐randomized clinical trial, which were of moderate‐to‐high risk of bias. All included trials used 1% topical cetirizine as the intervention with various regimens. Topical cetirizine was likely to be more effective than a placebo for treating AGA. In comparison with topical minoxidil, topical cetirizine appears to be less effective for improving total and vellus hair density, but it might have a longer‐lasting effect. Further, cetirizine might be as effective as minoxidil in improving hair diameter.ConclusionOne percent topical cetirizine may serve as a choice for treating AGA, especially for patients with a negative response to topical minoxidil. In order to fully understand the role of topical cetirizine for AGA, additional well‐designed RCTs are needed.
Gestational hypertensive disease and small for gestational age infants in twin pregnancy: A systematic review and meta‐analysis
Authors: Wang Mingbo , Wang Xin , Chen Zhifang , Zhang Feng 
Published: August 2022

AbstractAimThe review is to explore the connection between gestational hypertension diseases (GHD) and small for gestational age (SGA) in twin pregnancies.MethodsAccording to the recommendations of PRISMA, relevant studies were systematically searched through PubMed, Web of Science, Cochrane Library, Embase from inception until January 16, 2022. Subgroup analysis was performed according to chorionicity and diagnostic criteria of SGA. Odds ratios (OR) were assessed to judge the link between GHD and SGA in twin pregnant women. A random‐effect model was used to estimate the pooled hazard ratio when there was significant heterogeneity (I2 > 50%); otherwise, a fixed‐effect model was conducted.ResultsSeven articles containing 470 589 twin pregnant women were included. The increased risk of SGA was connected to the twin pregnancies complicated with GHD (OR = 1.57, 95% confidence interval [CI] = 1.10–2.24, p = 0.01). After subgroup analysis, the connection between SGA and GHD had no statistical significance (OR = 1.17, 95% CI = 0.95–1.44, p = 0.14) when the enrolled studies using the SGA diagnosis referred to singleton birth weight, but significant (OR = 2.14, 95% CI = 1.77–2.60, p<0.001) in the group using the SGA diagnosis referred to twin birth weight. Stratified by chorionicity, SGA was relevant to GHD in the dichorionic (DC) group (OR = 1.68, 95% CI = 1.17–2.42, p = 0.005), while not in the monochorionic (MC) group (OR = 1.68, 95% CI = 0.93–3.03, p = 0.09). More future articles are warranted to confirm these outcomes.ConclusionsOur review demonstrated that GHD in DC twin pregnancies was related to an enlarged risk of SGA. Two SGA diagnosis references led to different results. Twin pregnancies complicated with GHD were at significantly higher risk of SGA when twin birth weight reference was used.
When skinfolk are kinfolk: Higher perceived support and acceptance characterize close same‐race (vs. interracial) relationships for people of color
Authors: Debrosse Régine , Thai Sabrina , Brieva Tess 
Published: August 2022

AbstractPeople of color cope with racial stigma daily. In this context, support and acceptance from people who share similar racial/ethnic backgrounds can take a special importance. In two studies, using a national U.S. sample (n = 1618) and a term‐long weekly‐diary design (n = 103), Black, Latine, and Asian students received more support and acceptance from close same‐race (vs. interracial) relationships. Compared to White participants, Black and Latine participants reported greater support and acceptance from their relationships. Furthermore, greater support and acceptance in same‐race relationships predicted greater flourishing and lower depressive affect, even after controlling for support and acceptance in interracial relationships. These results underscore the importance of same‐race relationships for people of color in the U.S. In conjunction with practices addressing structural barriers, opportunities to connect with same‐race peers can nurture the flourishment of people of color in the U.S. and possibly other contexts in which they are stigmatized.
Is protecting older adults from COVID‐19 ageism? A comparative cross‐cultural constructive grounded theory from the United Kingdom and Colombia
Authors: Derrer‐Merk Elfriede , Reyes‐Rodriguez Maria‐Fernanda , Salazar Ana‐Maria , Guevara Marisol , Rodríguez Gabriela , Fonseca Ana‐María , Camacho Nicolas , Ferson Scott , Mannis Adam , Bentall Richard P , Bennett Kate M 
Published: August 2022

AbstractThe COVID‐19 pandemic impacted people's lives all over the world, requiring health and safety measures intended to stop the virus from spreading. This study explores whether an unintended consequence of these measures is a new form of ageism. We explore, using qualitative methods, the experiences of older adults living through the pandemic in the United Kingdom and Colombia. Although there were some small differences between countries, for the most part, the experiences were similar. We found that older adults reported that they were seen as a homogenous group and experienced both benevolent and hostile ageism and a loss of autonomy as a consequence of COVID‐19 protection measures. Participants from both countries expressed anger and frustration, and increased anxiety, and felt that their individuality was ignored. We recommend that policy‐makers, the media, and wider society consider the impact of such health and safety measures on older adults in preparing for future pandemics and health challenges.
A dual‐case analysis of the IP governance system in e‐commerce: Amazon and Alibaba
Authors: Wasaf Madanoor Mohamed , Zhang Jianhua 
Published: August 2022

AbstractConsidering the importance of intellectual property (IP) rights in e‐commerce, infringement of which is increasing the counterfeiting goods, affecting consumer's confidence and goodwill of e‐commerce, the purpose of this study is to examine the functionality of the IP governance system developed by e‐commerce companies. The study makes an in‐depth analysis of the IP governance system of the two major e‐commerce companies, Amazon.com and Alibaba.com, to comprehend the approach of these e‐commerce companies toward ensuring IP protection and protecting consumer's rights. In doing this, the study has taken qualitative dual‐case study research design which offers valuable insights about the effectiveness, practice, and applications of IP governance system in e‐commerce. Moreover, the dual‐case study approach contributes to develop a nomological framework. The study confirms that there is lack of harmonization in IP governance system and standard of IP protection which is essential for the sustainable development of e‐commerce and for protecting consumer rights. The significance of this study is the proposed recommendation for the regulatory body of the e‐commerce industry which serves as an institution, governing the business practice involved in e‐commerce to consider in reforming the IP governance system of the e‐commerce industry.
Genomics‐informed delineation of conservation units in a desert amphibian
Authors: Forester Brenna R. , Murphy Melanie , Mellison Chad , Petersen Jeffrey , Pilliod David S. , Van Horne Rachel , Harvey Jim , Funk W. Chris 
Published: August 2022

AbstractDelineating conservation units (CUs, e.g., evolutionarily significant units, ESUs, and management units, MUs) is critical to the recovery of declining species because CUs inform both listing status and management actions. Genomic data have strengths and limitations in informing CU delineation and related management questions in natural systems. We illustrate the value of using genomic data in combination with landscape, dispersal and occupancy data to inform CU delineation in Nevada populations of the Great Basin Distinct Population Segment of the Columbia spotted frog (Rana luteiventris). R. luteiventris occupies naturally fragmented aquatic habitats in this xeric region, but beaver removal, climate change and other factors have put many of these populations at high risk of extirpation without management intervention. We addressed three objectives: (i) assessing support for ESUs within Nevada; (ii) evaluating and revising, if warranted, the current delineation of MUs; and (iii) evaluating genetic diversity, effective population size, adaptive differentiation and functional connectivity to inform ongoing management actions. We found little support for ESUs within Nevada but did identify potential revisions to MUs based on unique landscape drivers of connectivity that distinguish these desert populations from those in the northern portion of the species range. Effective sizes were uniformly small, with low genetic diversity and weak signatures of adaptive differentiation. Our findings suggest that management actions, including translocations and genetic rescue, might be warranted. Our study illustrates how a carefully planned genetic study, designed to address priority management goals that include CU delineation, can provide multiple insights to inform conservation action.
3D vision‐based out‐of‐plane displacement quantification for steel plate structures using structure‐from‐motion, deep learning, and point‐cloud processing
Authors: Pan Xiao , Yang T. Y. 
Published: August 2022

AbstractIn this paper, a novel accurate and economical 3D computer vision‐based framework is proposed to quantify out‐of‐plane displacements of steel plate structures. First, a sequence of image frames of the steel plate structures of interest is collected. Second, using image association, structure‐from‐motion, and multi‐view stereo algorithms, a 3D point cloud of the steel plate structures and their surroundings is created. Third, an efficient 3D object detection method based on convolutional neural networks is developed and implemented to identify the steel plate structures in the 3D point cloud. Last, the out‐of‐plane displacements of the steel plate structures are quantified using point cloud postprocessing algorithms. The proposed framework has been implemented on a steel plate damper and a full‐scale steel corrugated plate wall panel, which are commonly used in structural and earthquake engineering applications. The results indicate the developed framework can successfully localize the steel plate components in the 3D scene and accurately quantify the out‐of‐plane structural displacements with an average accuracy of ∼1 mm. The implementation shows the proposed framework can accurately and efficiently quantify the out‐of‐plane displacements of steel plate structures in realistic engineering applications.
The Left(s) and Nationalism(s) in contemporary Western Europe
Authors: Dalle Mulle Emmanuel , Kernalegenn Tudi 
Published: August 2022

AbstractThis article introduces our themed section on The Left(s) and Nationalism(s), which provides a comparative analysis of the relationship between nationalism and different left‐wing parties in Western Europe. It highlights the innovative comparative perspectives offered by this themed section, which not only concerns a series of different geographical cases studies but also involves the ideological plurality of the Left. The larger research question that our contributors address is how different left‐wing parties have dealt with the inherent ideological tension between the universality claimed by the Left and the particularism inherent in nationalism, as a doctrine and a principle of political legitimacy. The article stresses three main contributions of our themed section: (1) Western European left‐wing parties do engage with the themes of nationalism and nationhood, but they often rely on convenient silence to solve some of the contradictions with their progressive ideology. (2) None of these parties have formulated thick versions of the respective national identities. (3) State‐wide left‐wing parties have used instrumental conceptions of nationhood to address the challenge of separatist parties, but only with mixed results.
Greens and the nation: Is small beautiful?
Authors: Kernalegenn Tudi 
Published: August 2022

AbstractDespite their distrust of big and centralised political units, their stance in favour of minorities and diversity, Greens do not skip the national issue but reimagine it with a bottom‐up and plural perspective under the form of regionalism. This article first study how ecologist theoreticians have defined different regionalist approaches, notably bioregionalism, ecoregionalism and econationalism, which became the basis of the Green approach on the national issue in Western Europe as early as the 1970s. Then, the paper comparatively focusses on Europe Ecology – The Greens Brittany and on the Scottish Green Party, assessing their analysis on their territory: whereas the first defend the project of an autonomous Brittany, the second is actively involved in favour of the independence of Scotland. In analysing the regionalism of the Greens, the article demonstrates that the green stance on the nation is not “identitarian” or “patriotic” but “cognitive”: it is devoid of nostalgia but on the contrary a tool for a multicultural and democratic Europe.
Norwegian nurses' perceptions of assisted dying requests from terminally ill patients—A qualitative interview study
Authors: Hol Hege , Vatne Solfrid , Strømskag Kjell Erik , Orøy Aud , Rokstad Anne Marie Mork 
Published: August 2022

AbstractThis study explores the perceptions of Norwegian nurses who have received assisted dying requests from terminally ill patients. Assisted dying is illegal in Norway, while in some countries, it is an option. Nurses caring for terminally ill patients may experience ethical challenges by receiving requests for euthanasia and assisted suicide. We applied a qualitative research design with a phenomenological hermeneutic approach using open individual interviews. A total of 15 registered nurses employed in pulmonary and oncology wards of three university hospitals and home care in one municipality were recruited. Four themes emerged from the analysis: (1) unprepared for the request; (2) meeting direct, indirect, and nonverbal requests; (3) working in a gray zone, and (4) feeling alone and powerless. The study found that nurses were unsure how to handle such requests due to professional uncertainty about assisted dying. Working in an environment where the topic is taboo made nurses morally uncertain, and some perceived this as moral distress. The hospital chaplain played a significant role in providing support to these nurses.
The secreted protein P75 of Lactobacillus rhamnosus GG regulates the SERT expression via EGFR and NF‐κB pathway
Authors: Wang Xin , Li Ying , Hou Junjie , Wang Zelan , Chen Yiming , Su Shuai , Xu Xin , Zhang Jie , Zhong Weilong , Wang Bangmao , Wang Yuming 
Published: August 2022

AbstractAimTo investigate the mechanism of Lactobacillus rhamnosus GG (LGG)‐secreted protein, P75, on the regulation of the expression of serotonin transporter (SERT) through the epidermal growth factor receptor (EGFR) and nuclear factor‐κB (NF‐κB) pathway.MethodsCaco‐2 cells were stimulated with LGG supernatant (LGG‐super), protein P75, AG1478, and TNF‐α. A rat model of post‐infectious irritable bowel syndrome (PI‐IBS) was constructed and treated with phosphate‐buffered saline and LGG‐super for 4 weeks. The levels of SERT, p‐EGFR, EGFR, p‐NF‐κB, NF‐κB, p‐IκB‐α, and IκB‐α were detected by quantitative real‐time polymerase chain reaction, Western blot, immunofluorescence, and immunochemistry. Luciferase assay was used to verify the link between NF‐κB and SERT promoter.ResultsLGG‐super and P75 upregulated the expression levels of SERT and p‐EGFR and decreased the expression levels of p‐IκB‐α and p‐NF‐κB. Dual luciferase assay result suggested that NF‐κB inhibited the activity of SERT promoter. In the animal experiments, 5‐HT concentration increased in the PI‐IBS Model group but decreased in the Model +LGG‐super group compared with the control. On the contrary, the expression of SERT protein was downregulated in the PI‐IBS Model group and improved in the Model +LGG‐super group. The expression of p‐EGFR was reduced and p‐NF‐κB was enhanced in the PI‐IBS Model group, whereas the expression of p‐EGFR and p‐NF‐κB was the opposite in the Model +LGG‐super group.ConclusionLGG supernatant and its secreted protein, P75, upregulate the expression of SERT by activating EGFR and inhibiting the NF‐κB pathway.
The IPGA1‐ANGUSTIFOLIA module regulates microtubule organisation and pavement cell shape in Arabidopsis
Authors: Chen Binqing , Dang Xie , Bai Wenting , Liu Min , Li Ying , Zhu Lilan , Yang Yanqiu , Yu Peihang , Ren Huibo , Huang Dingquan , Pan Xue , Wang Haifeng , Qin Yuan , Feng Shiliang , Wang Qin , Lin Deshu 
Published: August 2022

Summary

Plant cells continuously experience mechanical stress resulting from the cell wall that bears internal turgor pressure. Cortical microtubules align with the predicted maximal tensile stress direction to guide cellulose biosynthesis and therefore results in cell wall reinforcement. We have previously identified Increased Petal Growth Anisotropy (IPGA1) as a putative microtubule‐associated protein in Arabidopsis, but the function of IPGA1 remains unclear.

Here, using the Arabidopsis cotyledon pavement cell as a model, we demonstrated that IPGA1 forms protein granules and interacts with ANGUSTIFOLIA (AN) to cooperatively regulate microtubule organisation in response to stress.

Application of mechanical perturbations, such as cell ablation, led to microtubule reorganisation into aligned arrays in wild‐type cells. This microtubule response to stress was enhanced in the IPGA1 loss‐of‐function mutant. Mechanical perturbations promoted the formation of IPGA1 granules on microtubules. We further showed that IPGA1 physically interacted with AN both in vitro and on microtubules. The ipga1 mutant alleles exhibited reduced interdigitated growth of pavement cells, with smooth shape. IPGA1 and AN had a genetic interaction in regulating pavement cell shape. Furthermore, IPGA1 genetically and physically interacted with the microtubule‐severing enzyme KATANIN.

We propose that the IPGA1‐AN module regulates microtubule organisation and pavement cell shape.
Recent advancements for tropical cyclone data assimilation
Authors: Christophersen Hui , Sippel Jason , Aksoy Altug , Baker Nancy L. 
Published: August 2022

AbstractIn this review, data assimilation (DA) techniques used for tropical cyclones (TCs) are briefly overviewed. The strength and weakness of variational methods, ensemble methods, hybrid methods, and particle filter methods are also discussed. Several global numerical weather prediction models and their corresponding DA systems frequently used for TC forecasting and verification are described first. The DA research and development efforts in the operational regional model from the National Centers for Environmental Prediction's Hurricane Weather Research and Forecasting are then discussed in greater detail. Focused remarks on TC observations from reconnaissance, ground‐based radar, enhanced satellite‐derived atmospheric motion vectors and all‐sky satellite radiances and their impacts on TC analyses and forecasts are addressed. Recent TC DA advancements and challenges on better use of observations and more advanced DA methods for TC application are also briefly reviewed.