bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gel properties, physicochemical properties, and sensory attributes of white leg shrimp (Litopenaeus vannamei) surimi gel treated with sodium chloride (NaCl) substitutes
Authors: Chen Nuo , Jiang Qixing , Gao Pei , Yu Dawei , Yang Fang , Xu Yanshun , Xia Wenshui 
Published: October 2022

SummaryThis study investigated the effects of different NaCl substitutes on the gel properties, physicochemical properties, and sensory attributes of shrimp surimi gel to produce high‐quality reduced‐salt shrimp surimi gel. The results showed that CaCl2, calcium ascorbate (Vc‐Ca), and L‐arginine (L‐Arg) could significantly improve the gel strength and texture of shrimp surimi gel compared to NaCl. The addition of CaCl2, Vc‐Ca, and L‐Arg significantly increased the number of disulphide bonds and the content of β‐sheet structures compared to NaCl. The electrophoretic analysis revealed that CaCl2, Vc‐Ca, and L‐Arg had protective effects on the myosin heavy chain during thermal gelation. Additionally, CaCl2 and L‐Arg promoted the cross‐linking of myofibrillar proteins to form the denser and less porous microstructures, and thus improved the gel properties of shrimp surimi gel. In general, the introduction of L‐Arg as a substitute for NaCl acquired the best gel properties and sensory attributes of shrimp surimi gels, followed by CaCl2 and Vc‐Ca.
C3‐dependent effector functions of complement
Authors: Zarantonello Alessandra , Revel Margot , Grunenwald Anne , Roumenina Lubka T. 
Published: October 2022

SummaryC3 is the central effector molecule of the complement system, mediating its multiple functions through different binding sites and their corresponding receptors. We will introduce the C3 forms (native C3, C3 [H2O], and intracellular C3), the C3 fragments C3a, C3b, iC3b, and C3dg/C3d, and the C3 expression sites. To highlight the important role that C3 plays in human biological processes, we will give an overview of the diseases linked to C3 deficiency and to uncontrolled C3 activation. Next, we will present a structural description of C3 activation and of the C3 fragments generated by complement regulation. We will proceed by describing the C3a interaction with the anaphylatoxin receptor, followed by the interactions of opsonins (C3b, iC3b, and C3dg/C3d) with complement receptors, divided into two groups: receptors bearing complement regulatory functions and the effector receptors without complement regulatory activity. We outline the molecular architecture of the receptors, their binding sites on the C3 activation fragments, the cells expressing them, the diversity of their functions, and recent advances. With this review, we aim to give an up‐to‐date analysis of the processes triggered by C3 activation fragments on different cell types in health and disease contexts.
Nurses’ perceptions of using volunteer support in health care settings: A systematic scoping review
Authors: Crookes Kate , Saunders Rosemary , Kemp Vivien , Gallagher Olivia , Ghosh Manonita , Bulsara Caroline , Gullick Karen , O'Connell Bev 
Published: October 2022

AbstractAimsTo understand nurses’ perceptions of volunteer support in health care settings.BackgroundIncreasingly, volunteers provide specialised support to health care service users, requiring volunteers and nurses to work closely together. However, little is known about nurses’ perceptions of volunteer support.MethodsA scoping review was conducted following the PRISMA‐ScR checklist. A mixed‐methods convergent integrative approach was taken guided by the JBI framework. Quantitative data were transformed into qualitative data for synthesis and descriptive thematic analysis. Six databases were searched (CINHAL+, EMBASE, PubMed, Scopus, PsycInfo, ProQuest Health and Medical Collection) on 24 January 2022 using terms related to nurses, perceptions, volunteers and care settings, followed by a manual search. The search was limited to English language articles published during 2000–2022. Studies were included if they reported nurses’ perceptions of volunteers supporting care within any health care setting.ResultsOf the 943 records identified, 12 met the inclusion criteria. All 12 were included in the review following critical appraisal. Five themes were identified: perceived benefits for patients, volunteers providing support for nursing staff, nurses’ valuing volunteer support, nurses’ understanding of the volunteer role and nurses’ understanding of recruitment and training of volunteers.ConclusionNurses generally viewed volunteer support positively and perceived that it benefitted patients and assisted nurses. Some nurses raised concerns about the burden of additional supervision of volunteers and lacked knowledge of the volunteer role, recruitment and training. Emerging innovative models of nurse‐led volunteer support can maximise the contribution of volunteers and help overcome barriers to volunteer acceptance.ImplicationsThese findings will inform volunteer policies and provide guidance in developing volunteer support programs.
Qualitative study on barriers and coping strategies for dental care in autistic children: Parents' perspective
Authors: Junnarkar Vrushali Sameer , Tong Huei Jinn , Hanna Kamal Maher Batra , Aishworiya Ramkumar , Duggal Monty 
Published: October 2022

AbstractBackgroundChildren with autism spectrum disorders (ASD) face challenges in home oral care, accessing a dentist and accepting dental treatment.AimTo determine the barriers to dental care for autistic children in Singapore through the experiences and opinions of their parents.DesignA qualitative exploratory approach comprising semistructured interviews and a focus group discussion was used. Audio recordings were transcribed and coded into themes using NVivo 12 software.ResultsParticipants were 23 parents of autistic children aged 3–12 years. The following barriers were identified: (1) Sensory, physical and parental knowledge issues are related to toothbrushing difficulties and use of nonoptimally fluoridated toothpaste in autistic children. (2) Accessing dental services was hindered by a lack of parental knowledge on the importance of an early dental home, parental apprehension about the child's acceptance of dental care, lack of information on specialised dentists and perceived high cost of dental visits. Parental suggestions for improvements included understanding the child's sensory profile, more information on finding a suitable dentist and subsidisation of costs for multiple acclimatisation visits.ConclusionCaregivers' education, information about specialised dentists and the availability of specific dental care resources for autistic children in Singapore are needed for optimising their dental care.
Endoscopic approach to complex or recurrent pilonidal sinus: A retrospective analysis
Authors: Maione Francesco , D'Amore Anna , Milone Marco , Vertaldi Sara , Anoldo Pietro , Chini Alessia , Sorrentino Carmen , Marello Alessandra , Cantore Grazia , Maione Rosa , D'Angelo Salvatore , D'Alesio Nicola , De Simone Giuseppe , Servillo Giuseppe , De Palma Giovanni Domenico , Manigrasso Michele 
Published: October 2022

AbstractPilonidal Sinus is a benign, chronic disease that affects the hair follicles of the natal cleft of the sacrococcygeal area. Its ideal treatment is controversial, especially in complex or recurrent cases. The aim of this study is to evaluate the use of minimally invasive endoscopic approach in this setting. We enrolled patients affected by complex or recurrent sacrococcygeal pilonidal sinus from January 2015 through December 2020 who underwent Video‐Assisted Ablation of Pilonidal Sinus. All patients enrolled were re‐evaluated once a year with a standard physical examination. The patients included were 38. Recurrence rate at 1‐, 3‐ and 5‐years follow‐ups were 28.9%, 22.2% and 38.1% respectively. Of interest, the mean (SD) distance from the most lateral orifice to the midline was higher in group of patients with recurrence and the multivariate analysis demonstrated that it was the limiting factor, which influences the recurrence rate. In complex or recurrent pilonidal sinus disease with pits off the midline the endoscopic approach should not be the first choice. This makes us think that these cases should have their own classification to be identified and guide surgeons in choosing the appropriate approach.
Ten days (vs. May 10) make you rush: The effect of time descriptions on task scheduling
Authors: Jeong Yunjoo , Hwang Sanyoung , Suk Kwanho 
Published: October 2022

AbstractA time interval can be presented as a duration (e.g., 10 days) or a calendar date (e.g., May 10). This study examines the influence of time descriptions on task scheduling. Results of 10 studies (N = 2,129) present evidence that people tend to schedule their tasks earlier when the time interval is described as a duration than a date. This time description effect is accounted for by different mindsets. People tend to have an implemental mindset when time is described as a duration (vs. date) because of stronger feelings of being inside the time frame. This mindset affects decisions on scheduling when to initiate future tasks.
How tectonic, volcanic and climatic processes in Andean ‘sky islands’ shaped the diversification of endemic ground beetles
Authors: Murienne Jérôme , Barragán Álvaro , Manzi Sophie , Samaniego Pablo , Moret Pierre 
Published: October 2022

AbstractAimThe Andean superpáramo ecosystem, above c. 4200 m a.s.l., currently forms an archipelago of isolated ‘sky islands’ which provides a unique setting to study biogeography. However, there is still a poor understanding of how past geological events, together with past climatic changes, have shaped the distribution of life in this ecosystem. Our aim was to investigate the importance of biogeographical barriers in local diversifications and to analyse how populations have become isolated on current ‘sky islands’.LocationNeotropics, Andes, Páramo, Ecuador.TaxonColeoptera, Carabidae, Platynini, Dyscolus.MethodsWe first used distributional data of 45 superpáramo specialist species to define areas of endemism in northern Ecuador. We then selected 34 currently isolated populations of 12 species to perform a high‐throughput genome skimming approach encompassing the complete mitogenome and the complete nuclear ribosomal cluster. We also generated a time‐calibrated estimation for the diversification of the group, and compared it to geochronological data.ResultsA high proportion (60%) of the sampled species are microendemic, being restricted to a single mountain summit. Three mutually exclusive areas of endemism are limited by deep transverse valleys across the Andes, and Pliocene speciation events are related to these orogenic barriers. The phylogeny obtained from the genome‐skimming approach provides a robust base to analyse the diversification of superpáramo endemic species and populations throughout the Plio‐Pleistocene.Main conclusionsThe opening of the Interandean Valley did not play a significant role in the diversification of the group prior to the Pleistocene. More recently, multiple populations have become isolated on the superpáramo of various volcanoes by independently colonizing this habitat during repeated cycles of glacial–interglacial periods. Our results highlight the joint contribution of orogeny and climatic fluctuations for explaining the current patterns of distribution. Each species had a different colonization history, with its populations reaching the different volcanoes at different glacial–interglacial cycles. Our approach also can provide a powerful tool to constrain the geological processes responsible for the topographic changes along and across the Cordillera.
Study on the multitarget mechanism of alliin activating autophagy based on network pharmacology and molecular docking
Authors: Cheng Bijun , Li Tianjiao , Li Fenglin 
Published: October 2022

AbstractDue to the rapid development of bioinformatics, network pharmacology and molecular docking approaches have been successfully applied in the investigation of mechanisms of action. Here, we combined network pharmacology and molecular docking to predict the targets and reveal the molecular mechanism responsible for regulating autophagy by alliin. Based on the influence of alliin on autophagy, the targets of alliin were screened on the basis of different rules such as structural similarity by Pharmmapper, and genes associated with autophagy were collected from the GeneCards database. We focused on clarifying the biological processes and signalling pathways related to autophagy. Through the cytoHubba plug‐in and a series of integrated bioinformatics analyses, the top nine hub nodes with higher degrees were obtained. And finally, through the LibDock included in Discovery Studio 2019, molecular docking method was adopted to declare the reliability of the interaction between alliin and hub targets. The results suggest that alliin‐activated autophagy was possibly associated with pathways in cancer and the PI3K‐AKT signalling pathway. Furthermore, the potential targets (AKT1, MAPK14, MAPK, HSPA8, EGFR, HSP90AA1, SRC HSPA1A and HSP90AB1) were swimmingly screened on the basis of this practical strategy. Molecular docking analysis indicates that alliin can bind with AKT1 and EGFR with good binding scores. This network pharmacology could be an invaluable strategy for the investigation of action mechanisms of alliin‐activated autophagy. This study not only provides new and systematic insights into the underlying mechanism of alliin on autophagy, but also provides novel ideas for network approaches for autophagy‐related research.
Sex‐linked variations in the sagittal otolith biometry ofNemipterus randalli(Russell, 1986) from the eastern Mediterranean Sea
Authors: Yazici Ramazan 
Published: October 2022

AbstractFew studies have been conducted on the sagittal otolith shape and morphometry ofNemipterus randalli, and none of these studies has examined the effect of sexual dimorphism on the otolith morphology of this species, therefore this study aimed to contribute to knowledge about the otolith morphology ofN. randalli, an invasive fish species for the Mediterranean Sea. For this purpose, a total of 132 samples (51 female and 81 male) were obtained from İskenderun Bay with the help of commercial fishermen in November 2018. Relationships between otolith measurements and fish size were determined. Shape indices and elliptic Fourier coefficients were calculated. Significant differences were detected between males and females in all analysis. The sexes were separated from each other using both shape indices and elliptic Fourier coefficients. However, shape analysis was more effective in distinguishing sexes than traditional morphometric analysis. Asymmetry in the otolith morphology of sexes has been attributed to differences in the growth and sexual maturity of male and female fish. The results of this study indicated that sexual dimorphism inNemipterus randalliwas also reflected in the otolith morphology.
Extraction and encapsulation of bioactive compounds: A review
Authors: Peixoto Fernanda Barroso , Raimundini Aranha Ana Caroline , Nardino Danielli Andrea , Defendi Rafael Oliveira , Suzuki Rúbia Michele 
Published: October 2022

AbstractThe purposes of this article are to address the different bioactive compounds present in plant matrices, emphasizing the importance in choosing the extraction method in the yield and quality of extracted compounds, using techniques to determine antioxidant activity. As well as to expose the main mathematical models used in the kinetic study for process optimization and the influence of encapsulation on the conservation of bioactive compounds. Bioactive compounds are chemical molecules that have medicinal properties, acting in the prevention of diseases. The wide variety of bioactive compounds present in plants determines their characteristics, and the different combinations of these phytochemicals confer the particularities of each matrix. The extraction of compounds is extremely important, due to their industrial applications, being widely used in the production of food, supplements, cosmetics, and medicines, as ingredients or additives of these products. It was observed that new technologies are able to improve extraction efficiency obtaining higher yields and antioxidant activity than conventional methods. To obtain the extraction mechanism, aiming at optimizing time, several empirical kinetic models are used. The employability of mathematical models helps in the kinetic extraction profile, verifying the extraction profile of antioxidant compounds. Among these models, Hyperbolic was the one that best adapted to the studies performed. Then, for the preservation of the bioactive compounds obtained in the extraction process, encapsulation is carried out. This process prevents the degradation of compounds caused by external conditions such as light, heat, humidity, and increase in desirable properties, decreasing the evaporation of trapped active agents.
Food processing of egg white using ultrasonically generated microbubbles
Authors: Takita Takeshi , Makuta Tosinori 
Published: October 2022

AbstractWe developed the novel food processing method with directly generating microbubbles (MBs) in a highly viscous fluid like egg white with the hollow ultrasonic horn, which was impossible with conventional MBs generators. As for egg white processing with this method, we characterized the meringue produced by generating MBs made in the egg white and its use in cakes and puddings, hence, demonstrating the practicality of our method. These results reveal that MB meringue having high expansion rate than normally processed meringue and liquid egg white containing many MBs stably over a week are generated by the process with the hollow ultrasonic horn. In case of applying the egg white with MBs to cake and pudding, the expansion rate of cake increased and texture of cakes and puddings are changed.Practical ApplicationsWhen the egg white processed by hollow ultrasonic horn applied to cakes, those use affected the volume expansion and texture of the cake. These results indicate a possibility to process egg whites using microbubbles (MBs) by controlling the texture and volume. This technology can be widely applied not only to egg whites, but also to high‐temperature, high‐viscosity liquid foodstuffs such as jelly liquid, honey, and oil. If many MBs can be injected into these foods during the cooking or pre‐cooking process, it is possible to meet the needs for a wide variety of textures and tastes, and it is also expected to be applied to nursing food for the elderly who have swallowing difficulties.
Nondestructive detection of S‐ovalbumin content in eggs using portable NIR spectrometer and MPA‐CARS
Authors: Yao Kunshan , Sun Jun , Cheng Jiehong , Xu Min , Chen Chen , Zhou Xin 
Published: October 2022

AbstractThe feasibility of applying a low‐cost and portable NIR spectrometer to detect the S‐ovalbumin content of eggs was investigated in this study, and a model population analysis based competitive adaptive reweighted sampling (MPA‐CARS) algorithm was proposed to reduce the dimensionality of spectral data. The NIR spectra of egg samples with different storage periods were collected in the wavelength range of 900–1700 nm. Standard normal variate (SNV) and Savitzky–Golay1st derivative were used to preprocess the raw spectral data. Then, CARS and the proposed MPA‐CARS were applied to select effective wavelengths from the whole spectral range. Statistical results showed that MPA‐CARS had better feature extraction performance than CARS and the number of selected feature wavelengths was less. Support vector machine (SVM), back propagation neural network (BPNN) and extreme gradient boosting (XGBoost) were used to establish calibration models for predicting S‐ovalbumin content, in which the simplified XGBoost model based on MPA‐CARS feature wavelengths yielded the best performance, with R2P of 0.906 and RMSEP of 7.799%. Therefore, portable NIR has the potential to be a useful tool for S‐ovalbumin content detection. This could help food processing industry to arrange miniaturized NIR sensors to detect egg quality at different points in the egg supply chain.Practical applicationsS‐ovalbumin content is a freshness index of eggs and can affect the quality of processed foods. This study demonstrated the feasibility of using portable NIR spectrometer to detect the S‐ovalbumin content of eggs, which can help food processing agencies to implement low‐cost NIR sensors to detect egg quality at different stages of the supply chain.
Kinetic parameters of microbial thermal death in goat cheese whey and growth of surviving microorganisms under refrigeration
Authors: Santos Fábio Ribeiro dos , Leite Júnior Bruno Ricardo de Castro , Tribst Alline Artigiani Lima 
Published: October 2022

AbstractWhey is a byproduct of cheese production and, in smallholdings, is usually destined for animal feed or improperly disposed. To create alternatives for whey use, microbiological stabilization is the first step. Therefore, this study evaluated the kinetic parameters of the native microbiota thermal death (62–85°C) in goat cheese whey (GCW) and the growth of survivors after thermal processing performed at three different time–temperatures. The results showed that the come‐up time inactivated 1.0–1.8 log CFU/ml (≤71°C), 3.8 log CFU/ml (75°C), and more than 8 log CFU/ml (≥80°C). The inactivation data at 62, 65, 68, 71, and 75°C were fitted to the Bigelow model, from which D values of 65.7, 31.0, 11.7, 5.4, and 1.2 min, respectively, were determined. Using a first‐order equation, the z value was calculated as 7.5°C (R2 = 0.99). Processes time–temperatures were selected to achieve 2.5 (71°C/20 min), 0.5 (75°C/5 min), and <0.1 log CFU/ml (80°C/1 min) survivors. During the shelf life, microbiological growth was observed in all samples, reaching total bacterial counts (TBC) and psychrotrophic bacteria (TPC) >3 log CFU/ml between 14 and 28 days, with a predominance of non‐acidifying psychrotrophic bacteria. From the results, the time–temperature of 75°C/5 min was established as the best option for GCW processing, ensuring counts <2 log CFU/ml for up to 21 days.Practical ApplicationsThis study showed that the time–temperatures 71°C/20 min, 75°C/5 min, or 80°C/1 min, applied in a batch pasteurization process, were able to inactivate more than 5 log CFU/ml of the native microbiota of goat cheese whey. However, the shelf life of the product at 7°C was limited to 21 days due to the growth of the surviving population, even for samples that reached <0.1 log CFU/ml immediately after heating. Therefore, if extended shelf life is needed, additional barriers to microbial growth should be used. These data can be readily applied by artisanal goat cheese producers as a way to stabilize whey for later use, either in the development of whey beverages or for the use of whey as an ingredient in products.