bluuebunny/crossref_metadata_2025_split huggingface dataset:
DUREZA SUPERFICIAL DE UNA RESINA BULK FILL SEGÚN EL MOMENTO DE PULIDO
Authors: Ulloa Cueva Teresa Verónica 
Published: February 2022

Objetivo: Comparar la dureza superficial de una resina Bulk Fill pulida inmediatamente y a las 24 horas. Materiales y métodos: Se realizó un estudio comparativo in vitro prospectivo. Se confeccionaron 20 especímenes de resina FiltekTM Bulk Fill, según la ISO 4049 y se dividió en 2 grupos de 10. Grupo 1: pulido inmediato y Grupo 2: pulido a las 24 horas. Los valores obtenidos de cada indentación fueron convertidos en unidades Vickers (HV) y luego analizados por la prueba t-Student. Resultados: Los especímenes con pulido inmediato obtuvieron menor dureza superficial (121.3±20.01) con respecto al pulido a las 24 horas (147.7±19.88), siendo esta diferencia estadísticamente significativa (p=0.0084). Conclusión: La resina Bulk Fill pulida inmediatamente presentó menor dureza superficial que la pulida a las 24 horas.
Palabras clave: dureza, resinas compuestas, pulido.
INFLUENCIA DEL ARENADO SOBRE LA RESISTENCIA ADHESIVA DE UN POLIMERO HPP PARA CAD CAM
Authors: Cascante Calderón Marcelo Geovanny 
Published: February 2022

Resumen
Introducción: Fabricantes de materiales restauradores para CAD CAM están ofreciendo cada vez con más frecuencia nuevos productos que aseguran van a superar los que hasta ahora teníamos. Dentro de ellos, están los polímeros resinosos rellenos de cerámica que poseen buenas propiedades mecánicas y ópticas. Sin embargo, para que un material tenga éxito en la boca, también debe tener muy buenos valores de adhesión. Materiales y Métodos: 5 bloques de Brava Block fueron cortados para obtener 50 láminas de 14x14x1mm. 200 microtubos de resina convencional de 5 mm de altura x 0,8 mm de diámetro y posteriormente cementados sobre las láminas del polímero. Previo a la cementación, se arenó las superficies adherentes. Una vez arenados, al grupo inmediato se le procedió a cementar en ese momento los microtubos. Mientras que a los demás grupos se les retardó en 24, 48 y 72 horas el procedimiento adhesivo. Resultados: el Anova con un post hoc de Tukey encontró diferencias estadísticas significativas entre el grupo arenado y cementado inmediatamente, cuando comparado con los demás grupos. Conclusión: Este material polimérico alcanzó altos valores de adhesión aún después de envejecido, siempre y cuando se siga la técnica de cementación correcta.
Tipologi Ruang Komunal untuk Peningkatan Interaksi Sosial Penghuni pada Rumah Susun Sederhana Sewa di Jakarta
Authors: Sucipto Ilman Basthian 
Published: February 2022

Rumah susun sederhana sewa (rusunawa) merupakan bangunan dengan fungsi hunian yang dirancang agar untuk Masayarakat Berpenghasilan Rendah (MBR) yang dikategorikan memiliki daya beli rendah dan rentan secara ekonomi sehingga memerlukan dukungan lebih dari pemerintah dalam hal pemenuhan kebutuhan pokok, dalam hal ini penyediaan tempat tinggal yang layak. Dari hasil penelurusuran pada laman internet dengan kata kunci “rusunawa”, didapat pemberitaan tentang hal-hal negatif yang terjadi beberapa lokasi rusunawa di Jakarta, antara lain seperti tidak terisinya sebagian unit hunian, kawasan lingkungan yang terlantar dan tidak terpelihara, praktek prostitusi terselubung, penggerebekan sarang narkoba, kerusuhan dan penjarahan. Lantas muncul pertanyaan bagaimanakah desain rusunawa dengan ruang komunal yang layak dan memadai untuk kebutuhan interaksi sosial para penghuni rusunawa. Penelitian ini bertujuan untukmenemukan kriteria penyempurnaan desain rusunawa untuk meningkatkan kontrol sosial pada ruang komunal yang ada sekarang ini.Adapun metode yang digunakan dalam penelitian ini adalah metode deskriptif kualitatif interpretatif. Deskriptif terakit dengan penyajian temuan data-data kualitatif agar mudah dipahami, kemudian dilakukan interpretasi untuk menemukan pemahaman baru. Untuk pembangunan rusunawa ke depan, disarankan memperhatikan kebutuhan ruang komunal di tiap lantai hunian yang layak secara pencahayaan dan penghawaan tanpa sekat-sekat formalitas, dan nampaknya perilaku sosial budaya penghuni masih terpaku dalam kebiasaanya bahwa interaksi sosial bisa dilakukan di manapun dan kapanpun seperti ketika mereka tinggal di kampung.
Video Cinematik Produk Sebagai Sarana Promosi Pada Kampoeng Batik Kauman
Authors: Wandanaya Anita Bawaiqki , Mulyani Sri , Aditya Dwi Ravie 
Published: February 2022

Promotion Recognizing goods or services is an activity that must be carried out in order to increase the business being developed today that competes with others. A kind of tourism place also needs to carry out publicity activities, especially Kampoeng Batik Kauman in promoting the tourism sector and its products in the form of Batik. This research has a problem, namely the tourist destination that has not been updated according to changes in the tourism area in the Pekalongan area, therefore a new promotional video must be made to match the changes in tourism. The benefit is to expand Kampoeng Batik Kauman to the people through this cinematic video. In this study also use the method of Observation, Interview, Literature Review, Media Design and KPM. The results of this research will be in the form of audio-visual cinematic form to attract viewers, tourists and potential buyers to buy Batik, visit and understand every process of batik making in Kampoeng Batik Pekalongan and find out the latest information on the development of batik culture. The application of this cinematic video will later be uploaded on Youtube.
Keywords—Tourism; Culture; Promotion

Promosi Mengenali barang atau servis merupakan aktivitas yang harus dilakukan guna meningkatkan usaha yang sedang dikembangkan saat ini yang bersaing dengan lainnya. Semacam tempat pariwisata juga perlu melakukan aktivitas publisitas, khususnya Kampoeng Batik Kauman dalam mempromosikan sektor pariwisata dan produknya yang berupa Batik. Penelitian ini memiliki masalah yakni tujuan darmawisata yang belum di perbaharui sesuai dengan perubahan kawasan turisme di daerah Pekalongan oleh karena itu mesti di buat video promosi terbaru yang cocok dengan perubahan turisme. Manfaatnya untuk memperluas Kampoeng Batik Kauman kepada rakyat melalui video cinematik ini. Dalam penelitian ini juga memanfaatkan methode Observation, Interview, literature Review, Perancangan Media dan KPM. Hasil dalam penelitian ini nantinya berupa audio visual berbentuk cinematik guna menarik penonton, wisatawan dan calon pembeli untuk membeli Batik, mengunjungi dan memahami setiap proses pembuatan batik di Kampoeng Batik Pekalongan serta mengetahui info terbaru perkembangan budaya batik. Penerapan video cinematic ini nantinya akan di upload pada Youtube.
Kata Kunci—Pariwisata; Kebudayaan; Promosi
Pengaruh Profitabilitas, Sturktur Modal dan Ukuran Perusahaan terhadap Kualitas Laba dengan Kepemilikan Manajerial sebagai Variabel Moderating
Authors: Lusiani Siti , Khafid Muhammad 
Published: February 2022

The purpose of this study is to find empirical evidence regarding the effect of profitability, capital structure, and firm size on earnings quality with managerial ownership as a moderating variable. The sampling technique was determined by purposive sampling method which was based on the criteria set by the researcher and resulted into 79 units of analysis as observation object. The population in this study are manufacturing companies listed in the Indonesia Stock Exchange during 2016 to 2019 period. The data was collected using documentation method. The data was analysis used descriptive statistical analysis and moderate regression analysis with the tools IBM SPSS Statistic 21. The result of this study proves empirically that profitability and capital structure have an effect to earnings quality. Meanwhile firm size does not affect earnings quality. Furthermore, managerial ownership is able to moderate the effect of profitability and capital structure on earning quality. However, managerial ownership can not moderate the effect of firm size on earning quality. Future research are suggeste to expand the sample of companies from various sectors and increase the research period. Furthermore, it is recommended to add other variabels which might effect earnings quality. Regarding variable measurement it is also suggested to use another method measure each variable.
Highly Sensitive Capsaicin Electrochemical Sensor Based on Bimetallic Metal-Organic Framework Nanocage
Authors: Fang Xiao , Duan Rongshuai 
Published: February 2022

The content of capsaicin can be used as exotic markers of kitchen recycled oil. In this study, a bimetallic MOF nanocage (FeIII-HMOF-5) was successfully prepared by a one-step solvothermal method and used for electrode modification to prepare a highly sensitive electrochemical sensor for rapid detection of capsaicin. Capsaicin could be selectively immobilized onto the FeIII-HMOF-5 surface during infiltrating adsorption, thus exhibiting very excellent sensing performance. The detection conditions of the sensor were optimized. Under optimum conditions, the electrochemical sensor can linearly detect capsaicin in the range between 1–60 μM with a detection limit of 0.4 μM. In addition, the proposed electrochemical sensor showed excellent stability and selectivity. The real sample tests indicated the proposed electrochemical sensor was comparable to conventional UV spectrophotometry.
Comparison of Phenology Estimated From Monthly Vegetation Indices and Solar-Induced Chlorophyll Fluorescence in China
Authors: Wang Xin , Sun Zhongqiu , Lu Shan , Zhang Zhengxiang 
Published: February 2022

Phenology is an important biological indicator for monitoring terrestrial ecosystems and global change. Solar-induced chlorophyll fluorescence (SIF) emitted by chlorophyll has been proven to characterize vegetation photosynthesis and phenology. In this study, we used monthly normalized difference vegetation index (NDVI), enhanced vegetation index (EVI), and SIF products to qualitatively compare the effectiveness at detecting the phenological characteristics (SOS (start-of-season), EOS (end-of-season), and LOS (length-of-season)) over China during 2007–2013. The phenological characteristics determined by gross primary productivity (GPP) were applied as the reference to validate the phenological characteristics derived from NDVI, EVI, and SIF. The results demonstrated that the phenological characteristics derived from SIF were more consistent with that of GPP than VIs (NDVI and EVI) when considering all latitude grades, different elevation grades, and different land cover types in China. In the middle- and high-latitude regions, SOS derived from the vegetation indices (SOSVIs) did not deviate from those from GPP (SOSGPP) and SIF (SOSSIF), while in low latitudes, SOSVIs were about 20 d later than SOSSIF and SOSGPP. The VIs (EOSVIs) had a severe lag behind those of SIF (EOSSIF) in estimating the EOS at all latitudes. The EOSSIF had a deviation of fewer than 5 d compared with EOS estimated by GPP (EOSGPP), whereas the deviation of EOSVIs from EOSGPP was about 10–31 d across low to high latitude regions. The biases of SIF and VIs were due to the inconsistency between vegetation photosynthesis and leaf greenness. Also, VIs overestimated the LOS at all latitudes, the difference of LOS between estimated by NDVI and estimated by GPP was as long as 39 d in the high-latitude region. Our study suggests that SIF is suitable for estimating the phenological characteristics of vegetation regardless of different latitudes, elevation grades, and land cover types in China, providing a basis for SIF to study the vegetation phenological characteristics in a regional scope.
Comprehensive Analysis of LncRNA AC010789.1 Delays Androgenic Alopecia Progression by Targeting MicroRNA-21 and the Wnt/β-Catenin Signaling Pathway in Hair Follicle Stem Cells
Authors: Xiong Jiachao , Wu Baojin , Hou Qiang , Huang Xin , Jia Lingling , Li Yufei , Jiang Hua 
Published: February 2022

Background: Androgen alopecia (AGA), the most common type of alopecia worldwide, has become an important medical and social issue. Accumulating evidence indicates that long noncoding RNAs (lncRNAs) play crucial roles in the progression of various human diseases, including AGA. However, the potential roles of lncRNAs in hair follicle stem cells (HFSCs) and their subsequent relevance for AGA have not been fully elucidated. The current study aimed to explore the function and molecular mechanism of the lncRNA AC010789.1 in AGA progression.Methods: We investigated the expression levels of AC010789.1 in AGA scalp tissues compared with that in normal tissues and explored the underlying mechanisms using bioinformatics. HFSCs were then isolated from hair follicles of patients with AGA, and an AC010789.1-overexpressing HFSC line was produced and verified. Quantitative real-time polymerase chain reaction (qRT-PCR) and Western blotting were performed to verify the molecular mechanisms involved.Results: AC010789.1 overexpression promoted the proliferation and differentiation of HFSCs. Mechanistically, we demonstrated that AC010789.1 overexpression promotes the biological function of HFSCs by downregulating miR-21-5p and TGF-β1 expression but upregulating the Wnt/β-catenin signaling pathway.Conclusion: These results reveal that overexpression of AC010789.1 suppresses AGA progression via downregulation of hsa-miR-21-5p and TGF-β1 and promotion of the Wnt/β-catenin signaling pathway, highlighting a potentially promising strategy for AGA treatment.
Beneficial Impact of Interspecies Chimeric Renal Organoids Against a Xenogeneic Immune Response
Authors: Saito Yatsumu , Matsumoto Naoto , Yamanaka Shuichiro , Yokoo Takashi , Kobayashi Eiji 
Published: February 2022

BackgroundAnimal fetal kidneys have the potential to be used as scaffolds for organ regeneration. We generated interspecies chimeric renal organoids by adding heterologous rat renal progenitor cells to single cells from mouse fetal kidneys and applying the renal development mechanism of mouse fetuses to rat renal progenitor cells to examine whether rat renal progenitor cells can differentiate into renal tissues of the three progenitor cell lineages of kidneys between different species. Furthermore, we investigated whether chimeric renal organoids with an increased proportion of recipient cells reduce xenogeneic rejection.MethodsC57BL/6JJmsSlc mice (B6 mice) and Sprague-Dawley-Tg (CAG-EGFP) rat (GFP rats) fetuses were used as donors, and mature male NOD/Shi-scid, IL-2RγKO Jic mice (NOG mice) and Sprague-Dawley rats (SD rats) were used as recipients. First, fetal kidneys were removed from E13.5 B6 mice or E15.5 GFP rats and enzymatically dissociated into single cells. These cells were then mixed in equal proportions to produce chimeric renal organoidsin vitro. The chimeric organoids were transplanted under the renal capsule of NOG mice, and maturation of the renal tissues in the organoids was observed histologically. Furthermore, chimeric organoids were prepared by changing the ratio of cells derived from mouse and rat fetal kidneys and transplanted under the renal capsule of SD rats subjected to mild immunosuppression to pathologically analyze the strength of the xenogeneic immune response.ResultsThe cap mesenchyme was reconstructedin vitro, and nephron progenitor cells and ureteric buds were mosaically comprised GFP-negative mouse and GFP-positive rat cells. In thein vivoenvironment of immunodeficient mice, chimeric renal organoids mosaically differentiated and matured into renal tissues of three lineages. Chimeric renal organoids with high rates of recipient rat cells showed milder rejection than complete xenograft organoids. The vessels of recipient rats entered from the periphery of the transplanted chimeric renal organoids, which might reduce their immunogenicity.ConclusionInterspecies chimeric renal organoids may differentiate into mature renal tissues of each renal progenitor cell lineage. Furthermore, they may reduce transplant rejection compared with xenograft organoids.
Single-Port Laparoscopic Surgery for Adnexal Mass Removal During Pregnancy: The Initial Experience of a Single Institute
Authors: Han Ling , Wan Qi , Chen Yali , Zheng Ai 
Published: February 2022

ObjectiveSingle-port laparoscopy has become a feasible and safe approach for the management of benign adnexal masses during pregnancy. To our knowledge, there are few reports on the feasibility and safety of single-port laparoscopy for adnexal mass removal during pregnancy. Our study reports the use of single-port laparoscopy in adnexal mass removal during pregnancy in our hospital.MethodsWe included 10 cases of single-port laparoscopic surgery for adnexal mass removal during pregnancy in the West China Second University Hospital between January 2017 and March 2020. Median values were found using SPSS20. When the p-value was &lt;0.05, the median and interquartile range were used. All patients provided informed consent.ResultsThe following median values were recorded: surgical time, 112.50 min; blood loss, 25 ml; postoperative hospital stay, 3 days; postoperative pain [visual analog scale (VAS)] at 6 h, 3; and postoperative pain (VAS) at 24 h, 2. Our study reported no postoperative spontaneous abortions. There was one preterm birth.ConclusionSingle-port laparoscopy appears to be safe for both the mother and the fetus.
Validation of the International IgA Nephropathy Prediction Tool in the Greek Registry of IgA Nephropathy
Authors: Papasotiriou Marios , Stangou Maria , Chlorogiannis Dimitris , Marinaki Smaragdi , Xydakis Dimitrios , Sampani Erasmia , Lioulios Georgios , Kapsia Eleni , Zerbala Synodi , Koukoulaki Maria , Moustakas Georgios , Fokas Stavros , Dounousi Evangelia , Duni Anila , Papadaki Antonia , Damianakis Nikolaos , Bacharaki Dimitra , Stylianou Kostas , Gakiopoulou Hariklia , Liapis George , Sakellaropoulos Georgios , Papachristou Evangelos , Boletis Ioannis , Papagianni Aikaterini , Goumenos Dimitrios S. 
Published: February 2022

BackgroundImmunoglobulin A nephropathy (IgAN) is among the commonest glomerulonephritides in Greece and an important cause of end-stage kidney disease (ESKD) with an insidious chronic course. Thus, the recently published International IgAN prediction tool could potentially provide valuable risk stratification and guide the appropriate treatment module. This study aimed to externally validate this prediction tool using a patient cohort from the IgAN registry of the Greek Society of Nephrology.MethodsWe validated the predictive performance of the two full models (with or without race) derived from the International IgAN Prediction Tool study in the Greek Society of Nephrology registry of patients with IgAN using external validation of survival prediction models (Royston and Altman). The discrimination and calibration of the models were tested using the C-statistics and stratified analysis, coefficient of determination (RD2) for model fit, and the regression coefficient of the linear predictor (βPI), respectively.ResultsThe study included 264 patients with a median age of 39 (30–51) years where 65.2% are men. All patients were of Caucasian origin. The 5-year risk of the primary outcome (50% reduction in estimated glomerular filtration rate or ESKD) was 8%. The RD2 for the full models with and without race when applied to our cohort was 39 and 35%, respectively, and both were higher than the reported RD2 for the models applied to the original validation cohorts (26.3, 25.3, and 35.3%, respectively). Harrel's C statistic for the full model with race was 0.71, and for the model without race was 0.70. Renal survival curves in the subgroups (&lt;16th, ~16 to &lt;50th, ~50 to &lt;84th, and &gt;84th percentiles of linear predictor) showed adequate separation. However, the calibration proved not to be acceptable for both the models, and the risk probability was overestimated by the model.ConclusionsThe two full models with or without race were shown to accurately distinguish the highest and higher risk patients from patients with low and intermediate risk for disease progression in the Greek registry of IgAN.
Maintenance With Hypomethylating Agents After Allogeneic Stem Cell Transplantation in Acute Myeloid Leukemia and Myelodysplastic Syndrome: A Systematic Review and Meta-Analysis
Authors: Kungwankiattichai Smith , Ponvilawan Ben , Roy Claudie , Tunsing Pattaraporn , Kuchenbauer Florian , Owattanapanich Weerapat 
Published: February 2022

IntroductionHypomethylating agents (HMAs) seem to have a range of properties favorable to post-allogeneic hematopoietic stem cell transplantation (allo-SCT) maintenance in acute myeloid leukemia (AML) patients.Materials and MethodsThe Embase, MEDLINE, and Cochrane Central Register of Controlled Trials databases were independently searched by two investigators to identify relevant studies published inception to 18 November 2021. These trials compared HMA maintenance to observation following allo-SCT for AML or myelodysplastic syndrome.ResultsThe meta-analysis eligibility criteria were fulfilled by 14 studies. The overall survival and relapse-free survival of the HMA maintenance group were superior to the observation group, with a pooled risk ratio (RR) of 1.38 and 1.46, respectively. Moreover, the cumulative incidence of relapse was significantly lower in those who received HMAs. The HMA group also had lower non-relapse mortality compared with the observation group. Overall, the incidences of grades III–IV acute graft-vs.-host disease (GVHD) and chronic GVHD did not differ in both groups. However, when looking specifically at those receiving decitabine maintenance, the rate of chronic GVHD seemed to be lower compared with observation alone.ConclusionsThe current systematic review and meta-analysis illustrated that AML and MDS patients receiving HMA maintenance after allo-SCT had better outcomes in regards to OS, RFS, NRM, CIR as well as a reduced incidence of chronic GVHD.
Exploring the Diagnostic Performance of Magnetic Resonance Imaging in Ultrasound-Guided High-Intensity Focused Ultrasound Ablation for Abdominal Wall Endometriosis
Authors: Hu Shangying , Liu Yuhang , Chen Rongsheng , Xiao Zhibo 
Published: February 2022

ObjectiveThis study aimed to explore the clinical value of magnetic resonance imaging (MRI) combined with ultrasound-guided high-intensity focused ultrasound (USg-HIFU) for the diagnosis and treatment of abdominal wall endometriosis (AWE).MethodsMagnetic resonance imaging was performed before and after USg-HIFU. Information on clinical characteristics of patients, MRI characteristics of lesions, and treatment outcomes were collected. Thirty AWE lesions in 29 patients were examined before HIFU treatment, while 27 patients were examined after treatment. The results of MRI and color doppler ultrasound before surgery, as well as the volume and the apparent diffusion coefficient (ADC) values of the lesions before and after USg-HIFU treatment were compared. We also observed the clinical symptoms remission, recurrence, and ablation rates of the lesions in follow-up after HIFU treatment.ResultsThe locations of the 30 AWE lesions were identified by MRI before USg-HIFU treatment. Their sizes appeared larger on MRI than ultrasound (P &lt; 0.05). A total of 27 lesions were evaluated by MRI after USg-HIFU treatment, of which 92.6% (25/27) lesions were of high or slightly high signal intensity on T1-weighted images, and 77.8% (21/27) lesions were of mixed signal intensity on T2-weighted images. The mean ADC values of AWE lesions were 1.47 (1.20–1.59) × 10–3mm2/s and 1.86 (1.61–2.12) × 10–3mm2/s for pre-and post-HIFU treatment (P &lt; 0.05). Patients with higher ablation rates (&gt;50%) had a higher complete/partial remission rate than those with lower ablation rates (&lt;50%), and had a lower recurrence rate (P &lt; 0.05).ConclusionMRI is a useful tool for identifying the location, size, and concurrent changes of AWE before and after USg-HIFU treatment, which is beneficial for follow-up monitoring and defining treatment efficacy.