bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kinetochore- and chromosome-driven transition of microtubules into bundles promotes spindle assembly
Authors: Matković Jurica , Ghosh Subhadip , Ćosić Mateja , Barišić Marin , Pavin Nenad , Tolić Iva M. 
Published: February 2022

ABSTRACTMitotic spindle assembly is crucial for chromosome segregation and relies on bundles of microtubules that extend from the poles and overlap in the middle. However, how these structures form remains poorly understood. Here we show that overlap bundles arise through a network-to-bundles transition driven by kinetochores and chromosomes. STED super-resolution microscopy revealed that PRC1-crosslinked microtubules initially form loose arrays, which become rearranged into bundles. Kinetochores promote microtubule bundling by lateral binding via CENP-E/kinesin-7 in an Aurora B-regulated manner. Bundle separation is driven by steric interactions of the bundle-associated chromosomes at the spindle midplane since spindles with uncondensed or uncongressed chromosomes are narrower. In agreement with experiments, theoretical modeling suggests that bundles arise through competing attractive and repulsive mechanisms. Finally, perturbation of overlap bundles led to inefficient correction of erroneous kinetochore-microtubule attachments. Thus, kinetochores and chromosomes drive coarsening of a uniform microtubule array into overlap bundles, which promote not only spindle formation but also chromosome segregation fidelity.
Zebrafish Neuromesodermal Progenitors Undergo a Critical State Transition in vivo
Authors: Toh Kane , Saunders Dillan , Verd Berta , Steventon Benjamin 
Published: February 2022

SummaryThe transition state model of cell differentiation proposes that a transient window of gene expression stochasticity precedes entry into a differentiated state. As this has been assessed primarily in vitro, we sought to explore whether it can also be observed in vivo. Zebrafish neuromesodermal progenitors (NMps) differentiate into spinal cord and paraxial mesoderm at the late somitogenesis stages. We observed an increase in gene expression variability at the 24 somite stage (24ss) prior to their differentiation. From our analysis of a published 18ss scRNA-seq dataset, we showed that the NMp population possesses a signature consistent with a population undergoing a critical transition. By building in silico composite gene expression maps from our image data, we were able to assign an ‘NM index’ to each in silico NMp based on the cumulative expression of its neural and mesodermal markers. With the NM index distributions, we demonstrated that cell population heterogeneity of the NMps peaked at 24ss. We then incorporated stochasticity and non-autonomy into a genetic toggle switch model and uncovered the existence of rebellious cells, which we then confirmed by reexamining the composite maps. Taken together, our work supports the transition state model within an endogenous cell fate decision making event.
Testing for multiple bubbles: historical episodes on the sustainability of public debt in Spain, 1850–2020
Authors: Esteve Vicente , Prats María A. 
Published: February 2022

PurposeThis paper aims to analyze the dynamics of the Spanish public debt–gross domestic product ratio during the period 1850–2020.Design/methodology/approachThis study uses a recent procedure to test for recurrent explosive behavior (Phillipset al., 2011; Phillipset al., 2015a, 2015b) to identify episodes of explosive public debt dynamics and also the episodes of fiscal adjustments over this long period.FindingsThe identified episodes of explosive behavior of public debt coincided with fiscal stress events, whereas fiscal adjustments and changes in economic policies stabilized public finances after periods of explosive dynamics of public debt.Originality/valueThe longer than usual span of the data should allow the authors to obtain some more robust results than in most of previous analyses of long-run sustainability.
Construction tracking: implications of logistics data
Authors: Maxwell Duncan , Couper Rachel 
Published: February 2022

Purpose
Construction suffers from “peculiarities” that concern the temporary natures of the construction site, project teams and unique product design. Considering the digital transformation of construction, new solutions are being investigated that can provide consistent data between changing projects. One such source of data manifests in the tracking of logistics activities across the supply chain. Construction logistics is traditionally considered a site management activity focused solely on the “back end” of projects, but an expanded logistics focus can unlock new avenues of improvement. This study aims to understand the requirements and benefits of such a consistent thread of data.

Design/methodology/approach
From a research project with one of Australia’s largest contracting companies, this paper details a series of construction tracking tests as an empirical case study in using Bluetooth low energy aware tracking technology to capture data across the manufacture, delivery and assembly of a cross-laminated timber structural prototyping project.

Findings
The findings affirm the tracking of expanded logistics data can improve back-end performance in subsequent projects while also demonstrating the opportunity to inform a project’s unique front-end design phase. The case study demonstrates that as the reliability, range and battery life of tracking technologies improve, their incorporation into a broader range of construction activities provides invaluable data for improvement across projects.

Originality/value
As a live case study, this research offers unique insights into the potential of construction tracking to close the data loop from final site assembly back to the early project design phase, thus driving continual improvement from a holistic perspective.
A new tri-source symmetric cascaded multilevel inverter topology with reduced power components
Authors: Pradeep Jayarama , Vengadakrishnan Krishnakumar , Palani Anbarasan , Sandirasegarane Thamizharasan 
Published: February 2022

Purpose
Multilevel inverters become very popular in medium voltage applications owing to their inherent capability of reconciling stepped voltage waveform with reduced harmonic distortion and electromagnetic interference. They have several disadvantages like more number of switching devices required and devices with high voltage blocking and need additional dc sources count to engender particular voltage. So this paper aims to propose a novel tri-source symmetric cascaded multilevel inverter topology with reduced number of switching components and dc sources.

Design/methodology/approach
A novel multilevel inverter has been suggested in this study, offering minimal switch count in the conduction channel for the desired voltage level under symmetric and asymmetric configurations. This novel topology is optimized to prompt enormous output voltage levels by employing constant power switches count and/or dc sources of voltage. The topology claims its advantages in generating higher voltage levels with lesser number of voltage sources, gate drivers and dc voltage sources.

Findings
The consummation of the proposed arrangement is verified in Matlab/Simulink R2015b, and an experimental prototype for 7-level, 13-level, 21-level, 29-level, 25-level and 49-level operation modes is constructed to validate the simulation results.

Originality/value
The proposed topology operated with six new algorithms for asymmetrical configuration to propel increased number of voltage levels with reduced power components.
Productivity and job reallocation: evidence from the Indian manufacturing
Authors: Goswami Diti 
Published: February 2022

PurposeThis study aims to examine the association between productivity growth and job reallocation in terms of job creation and job destruction. It also finds this productivity employment relationship for heterogeneous labor market institutions of the Indian states.Design/methodology/approachThe paper uses longitudinal data of the Annual Survey of Industries of Indian manufacturing from 2009–2010 to 2015–2016 and employs fixed-effect multinomial logistic regression.FindingsThe paper finds a mixed result of total factor productivity (TFP) increase on employment. An increase in TFP is positively associated with employment by reducing the probability of destroying jobs, while adversely associated with employment by reducing the probability of creating jobs. The negative association of the increase in TFP on employment is more in the Indian states with strict labor regulations.Research limitations/implicationsThe relationship between TFP and employment can be endogenous. TFP is calculated as output changes that are not explained by inputs, capital and labor. So, job creation/destruction may affect TFP by changing the composition of employment and/or returns on labor/capital. In addition, this study is only restricted to Indian organized manufacturing.Practical implicationsThe results from this study help deeply understand the Indian labor market. In particular, it provides valuable insights into the “jobless growth” in Indian manufacturing and the recent changes in labor laws.Social implicationsThe findings from this study provide useful information to enhance the robust growth of productive jobs and efficient reallocation of labor.Originality/valueUnlike most papers, which analyzed the relationship between productivity growth and net employment changes, the present paper finds the relationship between improvement in productivity and job reallocation in terms of simultaneous creation of new jobs and destruction of existing jobs. In addition, the paper links this relationship with the existing heterogeneous labor laws of the Indian states.
Circular economy, cradle to cradle and zero waste frameworks in teacher education for sustainability
Authors: Kowasch Matthias 
Published: February 2022

Purpose
Sustainability is a major concern in education policies. This paper aims to describe how alternative economic education including concepts of the circular economy (CE), cradle to cradle (C2C) and zero waste can be addressed by teacher education. The author asks to what extent such alternative concepts contribute to sustainability education and transitions and empower students and future teachers, through fieldtrips.

Design/methodology/approach
Fieldtrips to three extracurricular learning places in Graz (Austria) – a plastic waste disposal facility, an upcycling design atelier and a supermarket without packaging – were organized as part of a university seminar on economy and sustainability. Based on student essays reflecting the fieldtrips, this praxeological paper provides insights on how students perceive awareness-raising and innovative responses to mass consumption, recycling/upcycling and waste prevention issues.

Findings
Including altermatic economic frameworks, such as CE/C2C and zero waste, into teacher education contributes to reflections on the economic growth paradigm and promotes more sustainable futures. In various statements, students highlighted social-ecological change and awareness-raising. They rather focussed on recycling, upcycling and (plastic) packaging than on the problematic eco-efficiency of downcycling.

Originality/value
Alternative economic concepts can be addressed and critically reflected in sustainability education, even if rarely taught. Although the extracurricular learning places described offer partial solution from the perspective of degrowth, they can serve as an eye-opener and promote alternative economic education, where students can share experiences, knowledge and creative ideas to engage in sustainability transitions.
The impact of platform flexibility and controls on platform attractiveness: an empirical study from the seller's perspective
Authors: Pan Meiyu , Huang Rui , Chi Maomao , Hu Shangui 
Published: February 2022

PurposeThe e-business platform has become a major driver for economic growth and development. The economic success of an e-marketplace greatly depends on the extent to which buyers and sellers are attracted to enter and actively participate in the e-business platform. Existing literature lacks empirical examination of factors influencing e-business platform attractiveness (EBPA) from a seller's perspective and understudies the interplay between technical and managerial considerations.Design/methodology/approachBased on the literature on network economy, modular systems theory, control theory and social exchange theory, the paper proposed that platform flexibility and platform control (PC) would affect EBPA through both direct and interaction effects. From a survey of platform sellers, the paper explored the influencing mechanisms of EBPA using hierarchical regression and fuzzy-set qualitative comparative analysis (fsQCA) to understand the statistical associations and the set relations of the conjunctions and conditions.FindingsThe paper found that platform flexibility (PF), process control and clan control (CC) positively affected EBPA. In addition, the interaction between PF and process control demonstrated a substitution effect on EBPA, and the interaction between PF and CC demonstrated a complementary effect on EBPA. Also, the authors found that the interaction between process control and CC demonstrated a complementary effect on EBPA. fsQCA provided the configurations of causal recipes associated with EBPA.Originality/valueFrom a seller's perspective, the paper presents both theoretical explanation and empirical evidence for how design factors (e.g. PF) and governance factors (e.g. process control and CC) may interplay to influence EBPA.
Does development deter crime against women? Panel evidence from India
Authors: Gupta Suhasini , Sahoo Pradeep Kumar , Paltasingh Kirtti Ranjan 
Published: February 2022

PurposeThis paper investigates the deterrence effect of development on crime against women in India. Specifically, the authors examine the deterrence effect of the composite development index, i.e. Human Development Index (HDI), along with other variables acting as development indicators such as women’s employment, the relative strength of women in the police force, urbanization, etc., on crimes against women.Design/methodology/approachThis study adopts a fixed effect within-group (WG) panel regression model and pooled regression model on the data of 28 states over 20 years from 2000 to 2019. For checking the robustness of the results, the authors use the estimation from the system generalized method of moments.FindingsThe results confirm the deterrence effect of development as measured by the HDI and female labor force participation on various crimes against women. In addition, female feticide representing the socio-cultural attitude toward women turned out to be another significant determinant of almost all types of crime against women. Further, the study also finds the deterrence effect of variables such as police expenditure, the relative strength of women in the police force, urbanization and arrest rate on various crimes against women.Originality/valueThis research paper is unique because it tries to examine the deterrence hypothesis of development by taking a composite index of development, i.e. HDI and other variables at the state level in the Indian union.
The interest cost of split-rated municipal bonds before and after Moody's recalibration in 2010
Authors: Benson Earl D. , Marks Barry R. 
Published: February 2022

PurposeIn April and May of 2010 Moody's recalibrated its municipal bond ratings to a global scale, the system they use for other asset classes and the same scale used by Standard and Poor's (S&P). The authors investigate the impact of Moody's recalibration on true interest cost (TIC) of competitively-sold, uninsured, new bond issues with split bond ratings, by looking at a sample of bond issues before recalibration (1997–2010) and after recalibration (2010–2017).Design/methodology/approachTwo different hypotheses are tested for each period to estimate whether TIC remains the same when the S&P rating is higher (H1) than Moody's rating or lower (H2) compared to bond issues for which the S&P and Moody's rating are the same. Further, two additional hypotheses are tested. H3 tests whether the impact of having a higher rating from S&P is the same as having a lower rating from S&P. H4 tests whether the impact of having a split rating is the same in the pre- and post-recalibration period.FindingsTests suggest that before recalibration a higher S&P rating leads to significantly lower interest costs, but a lower S&P rating does not lead to significantly higher costs. After recalibration, a higher S&P rating leads to significantly lower interest costs; however, a lower S&P rating leads to significantly higher interest costs for the bonds in the sample. The findings also suggest that the rating systems of Moody's and S&P became more similar to each other after recalibration and that the impact on interest cost of a higher S&P rating is reduced after the recalibration.Originality/valueIt appears that a given Moody's rating (which used higher credit standards in the period before recalibration) was more influential than the S&P rating prior to recalibration because investors “ignored” a lower S&P rating during this period. After recalibration, the lower S&P rating was no longer ignored by investors. Therefore, Moody's recalibration seems to have had the intended effect of moving the credit standards of the two rating agencies more into parity. This provides value to investors since they may now assume, unlike the situation in the pre-recalibration period, that similar ratings from the two companies provide similar information about the probability of default and loss that would occur following a default. From the standpoint of regulators, the municipal credit information is easier to understand and is more transparent for investors.
The disinformation warfare: how users use every means possible in the political battlefield on social media
Authors: Steinfeld Nili 
Published: February 2022

PurposeThe study aims to investigate the predictors of engaging in combat against the spread of misinformation and disinformation online, and of actively sharing disinformation by users. The study advances an understanding of user active engagement with disinformation as political participation, especially linked to violent activism, in alignment with the view of disinformation as political weapon.Design/methodology/approachA survey of 502 Israeli internet users inquired into respondents' political participation, trust and orientation, definitions and perceptions of “Fake News,” and previous engagement in sharing misinformation disinformation items, combating or intention to combat against the spread of disinformation.FindingsIn addition to identifying predictors for each practice, the findings indicate that sharing and combating against disinformation are closely linked. They are also all directly linked to political participation of various kinds. Most interestingly, working for a political party significantly correlates with knowingly sharing disinformation items, and participating in illegal or violent political activities significantly correlates with knowingly sharing and actively participating in combat against disinformation.Originality/valueThe spread of disinformation online and its implications has received much scholarly as well as public attention in recent years. However, the characteristics of individual users who share or combat against the spread of disinformation online, as forms of political participation, have not been examined. This study fills this gap by inquiring into such practices and the behaviors, perceptions and demographics that predict them.
Cost‐effective models for delivering behaviour analysis teaching in UK schools and local authorities
Authors: McCandless Susan , Hoerger Marguerite 
Published: February 2022

Education programmes based on behaviour analysis are often used to teach children with learning disabilities. A common application of behaviour analysis is Early Intensive Behaviour Intervention (EIBI), which is evidence‐based, but most children in the UK do not have access to this approach. EIBI is usually implemented for 30 to 40 hours per week, over two years. High levels of supervision from behaviour analysts are essential to ensure EIBI's effectiveness. A recent cost‐effectiveness study concluded that EIBI was not cost‐effective: while the children make progress relative to treatment as usual, the outcomes did not justify the cost of the intervention. Other low‐cost models of delivery need to be considered. School‐based models used in the UK may provide cost‐effective and sustainable ways to use applied behaviour analysis in schools. They could be used in other local authorities to increase access to an education that includes behaviour analysis.
Complicity in sociology and community‐based participatory research with Marshallese
Authors: McElfish Pearl A. , Purvis Rachel S. , Riklon Sheldon , Willis Don E. 
Published: February 2022

AbstractComplicity with colonialism can be reflected in a particular approach to research, whose interests it serves, and who has power or ownership over the research process. It can also be reflected in neglect, inaction or methodological erasure of groups historically subjected to domination by colonial empires. Social scientists have often failed to account for colonialism's role or the complicit role they have played. We provide a brief historical overview of colonialism in the Marshall Islands and the role social scientists—and their methodological and epistemological approaches—played in the US empire's expansion into the region. We discuss the tenets of Community Based Participatory Research (CBPR), setting the research agenda, co‐direction of the research process, research team membership, collaboration challenges, and the action and outputs which have come from our team's health disparities research among the largest Marshallese population in the continental US. We argue CBPR is a promising but imperfect approach to guarding against complicity within medical sociology and situate our methodological approach within ongoing debates regarding objectivity and advocacy within sociology. We reflect on successes and shortcomings of our CBPR efforts to address health disparities among Marshallese, as well as how those successes and shortcomings overlap with questions of complicity.