bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validation of the An Abbreviated Version of the Mindful Eating Questionnaire in Turkish Adults
Authors: Kaya Seda , Açık Murat , COŞKUN Ayfer BEYAZ , YILMAZ Feray ÇAĞIRAN 
Published: July 2022

Abstract
Purpose: To adapt and validate the an abbreviated version of the Mindful Eating Questionnaire (MEQ-18) to the Turkish language for a Turkish adult population.Methods: This cross-sectional study included 709 participants aged between 18-65 years living in the province of Elazig. The data was collected through a voluntary face-to-face survey. The questionnaire was included their general characteristics and the MEQ-18 and Eating Attitude Test-26 (EAT-26). Confirmatory factor analysis (CFA) was used to test the validity of the MEQ-18. Statistical analyzes were conducted using the R-Project program and IBM SPSS Statistics for Windows 26.0.Results: The overall content validity index was 0.93. A confirmatory factor analysis was conducted for the two sub-scales and reduced the abbreviated of MEQ to 18 items. The Cronbach’s alpha coefficient was 0.718 for the MEQ-18 total factor scores and Cronbach alpha values for awareness, and disinhibition were found to be 0,843 and 0,789, respectively. The minimum discrepancy per degree of freedom = 4.914 and the model generally fit well to the structure (RMSEA = 0.074, CFI = 0.934, SRMR = 0.079, TLI = 0.925, GFI = 0.968, AGFI = 0.959).Conclusions: The findings of study showed that the psychometric properties of the abbreviated MEQ adapted into Turkish were acceptable through construct and internal consistency reliability.Level of evidence: Level V, descriptive cross-sectional study.
Effect of different stages of lactation on erythrocyte osmotic fragility, blood leucocyte entities, and milk somatic cell of Badri cattle
Authors: Thakur Swati , Huozha R. , Dhara Souvik , Maiti Abhinaba , Verma Megha , Ramanarayanan Sivaraman , Rastogi Sunil Kumar , Shahi Bijendra Narayan , Batra Munish 
Published: July 2022

Abstract
The present investigation was undertaken to study the effect of different stages of lactation on erythrocyte osmotic fragility, blood leucocyte indices and milk somatic cell count in indigenous Badri cattle. Badri is first registered indigenous, dual purpose cattle breed of the state Uttarakhand (India) mainly reared in hilly areas of the state. Osmotic fragility evaluates the stability of erythrocyte membrane to osmotic stress. Leucocytes form defence mechanism against invading micro-organisms. Somatic cell count is an indicator of udder health. The study was carried out in forty healthy Badri cows divided into five groups according to their lactation stages viz. group 1 (0–60 days), group 2 (61–120 days), group 3 (121–180 days), group 4 (181–240 days) and group 5 (to be dried off). Erythrocyte osmotic fragility, blood total leucocyte count (TLC), differential leucocyte count (DLC) and milk somatic cell count (SCC) were estimated. The percent hemolysis of erythrocytes among different groups was significant (p < 0.05) at 0.9% and 0.5% saline concentrations. A significant effect (p < 0.05) of lactation stages on blood lymphocytes, neutrophils and milk somatic cell count was observed.
Disability, Work Status, and Deprivation among working age-group: Shreds of evidence from NSS 76 TH round Data
Authors: Gupta Jagriti , Govil Dipti , Singh Angad 
Published: July 2022

Abstract
Background: In India, where most of the population is in the working-age group and as per census 2011, 2.1 % of the total population are disabled, the biggest concern is the onset of different types of disability among the working-age population as it directly affects the nation productivity and economy. This study aims to assess the consequences of disability in terms of loss and change of work experiences by the working-age population and to calculate the disability deprivation index of India and its states.Methods: Multinomial logistic regression has been used to find the impact of the onset of disability on the working-age population. The disability deprivation index has been calculated for Indian states. Results: The overall prevalence of disability is 2.2 %. Persons who worked before the onset of disability, maximum of them losses their work due to the onset of disability. The disability deprivation index shows which state is more deprived. Highest the ranking is the lowest deprivation, Kerala is the lowest deprived state, and Bihar is the highest. Conclusion: There are many facilities provided by government and NGOs for disabled, however the condition of disabled in India is severe since the availability of these facilities is limited to certain proportion of the population, there is requirement to upsurge these services and spread them. The disability deprivation index of majority of states of India lies in category of poor living conditions. The government and NGOs should work in specific direction so that quality of life of person with disability can improve.
Numerical Prediction of Impulse and Overpressure for a Green High Energy Metal Organic Framework (HE-MOF) Using CFD
Authors: Noorpoor Zeinab , Tavangar Saeed , Soury Hosein , Hoseini Ghorban 
Published: July 2022

Abstract
In this investigation, a geometry of three-block obstacles has been studied under the explosion of a green high-energy metal organic framework (HE-MOF) martial with the implementation of a computational fluid dynamics (CFD) domain. Control volume generated mesh in SnappyHexMesh was utilized with boundary conditions and initial values to resolve the system of equations in explosiveSonicFoam (a modified module of OpenFoam technology). The numerical simulation method was validated using the experimental data obtained by Kingery-Bulmash trinitrotoluene (TNT). The large eddy simulation (LES) method as a turbulence model and the Beker-Kistiakowsky-Wilson (BKW) model as a real gas equation of state were employed to enhance the accuracy of simulations. [Cu(Htztr)2(H2O)2]n was selected as HE-MOF due to its appropriate explosive specifications, which come from its special chemical structure. Pressure history on the domain has been measured at various points. TNT equivalency validation had shown a deviation error of 3–14% and 20% for overpressure and impulse, respectively in comparison with Kingery-Bulmash empirical data. Further, it was shown that block structures reduced 26.4% of peak incident pressure. The results of the current study suggested that HE-MOF produced an impulse of 2.5 and 2.28 greater than TNT in the non-obstructed and the obstructed sides of the explosion, respectively. Supersonic flow visualization clearly showed positive reflected and incident pressure surface. The comparisons between TNT and selected HE-MOF demonstrated higher blast wave intensity and under-effected areas of HE-MOF.
Insights from observations and manipulative experiments into competition between mangroves and salt marsh vegetation
Authors: Hockaday Alyssa C , Armitage Anna R. , Pennings Steven C. 
Published: July 2022

Abstract
Ecologists use multiple methods for studying interspecific competition, but different approaches may give different answers. We compared four methods to quantify the competitive interactions between Avicennia germinans (black mangroves) and salt marsh vegetation in Texas, USA: two different methods of sampling a large (24 x 42 m) mangrove removal experiment, a transplant experiment conducted within the large experiment, and an observational study comparing sites naturally dominated by marsh or mangrove vegetation. As expected, mangroves strongly suppressed the cover and biomass of salt marsh plants. But our understanding of the strength of these interactions varied depending on the study method used, the plant species studied, and the spatial scale considered; different processes influencing community assembly. The transplant experiment isolated the effects of competition driven only by the presence or absence of mangroves in the immediate (3x3 m plot) vicinity of the transplanted plants. In contrast, the observational study examined the combined effects of dispersal, abiotic suitability and competition as a function of the cover of mangroves at the larger plot scale. Combining the approaches in areas with levels of mangrove cover varying from 45% to 97% provided insight into how results from the local scale could be extrapolated to the landscape. Although mangroves may compete strongly with neighboring marsh plants growing in their immediate vicinity, marsh plants may not be totally eradicated from sites colonized by mangroves, but instead may persist on the landscape at low densities in stressful habitats that offer a refuge from competition.
E2F1-initiated transcription of PRSS22 promotes breast cancer metastasis by cleaving ANXA1 and activating the FPR2/ERK signaling pathways
Authors: Song Lin , Song Lin , Li Hui , Li Hui , Ma Ran-Ran , Ma Ran-Ran , Liu Sen , Liu Sen , Zhang Guo-hao , Zhang Guo-hao , Guo Xiangyu , Guo Xiangyu , Zhao Ruinan , Zhao Ruinan , Zhang Kai , Zhang Kai , Wu Xiaojuan , Wu Xiaojuan , Gao Peng , Gao Peng 
Published: July 2022

Abstract
Breast cancer (BC) is the most common malignant tumor in women worldwide. Metastasis is the main cause of BC-related death. The specific mechanism of BC metastasis remains obscure. Recently PRSS22 was discovered to be involved in tumor development. However, its detailed biological function and regulation mechanism in BC remain unclear. Here, we characterized that the PRSS22 expression level was upregulated in BC tissues compared with non-tumorous breast tissues. Dual Luciferase assays, bioinformatics analyses and chromatin immunoprecipitation (ChIP) assays indicated that the transcription factor E2F1 directly bounded to the PRSS22 promoter region and activated its transcription. Functionally, upregulation of PRSS22 promoted invasion and metastasis of BC cells in vitro and in vivo, whereas knockdown of PRSS22 elicited inhibition function. Mechanistically, the combination of PRSS22 and ANXA1 protein in BC cells was firstly screened by protein mass spectrometry analyses, and then confirmed by Co-immunoprecipitation (Co-IP) assays and Western blot assays. Co-overexpression of PRSS22 and ANXA1 could promote migration and invasion in BC cells. We further demonstrated that PRSS22 could promote the cleavage of ANXA1 and produce a N-terminal peptide, which could initiate the FPR2/ERK signaling axis to increase the aggressiveness of BC.
Correlation Between Muscle Strength and Amount of Lean Mass in Pre- surgical Patients with Colorectal Cancer
Authors: Marchetti Beatriz Schirrmeister , Freitas Josiane de Paula , Miola Thais Manfrinato 
Published: July 2022

Abstract
Introduction: Nutritional status is one of the independent factors that most influence postoperative outcomes in elective colorectal surgeries. Adequate muscle mass and strength contribute to the reduction of complications and can be evaluated in the preoperative period as prognostic markers. Objective: To compare lean mass (LM) with muscle strength (MS) in patients with colorectal cancer in the preoperative period. Methods: A retrospective study carried out with 87 patients from the nutrition clinic of the A. C. Camargo Cancer Center Hospital. Dynamometry was used to assess MS and bioelectrical impedance analysis (BIA) was used to assess LM. Results: Most of the results were male (51.7%) with a mean age of 60.7 years. The most prevalent Body Mass Index (BMI) classification was normal weight (50.6%) and the sample showed a higher prevalence of resistant LM and MS (70.1% and 67.8%, respectively). Only 9.2% of the sample presented both MS and LM inadequate. LM was significantly associated with age (p=0.011), BMI (p<0.001), phase angle (PA) (p=0.016) and oncological diagnosis (p=0.042). MS was significantly associated only with age (p<0.001) and PA (p=0.036). LM showed no significant association with MS (p=1.00). Conclusion: This study did not notice an association between lean mass and muscle strength in patients with colorectal cancer. More prospective nutritional therapy is needed to understand this relationship, although both measures can be directed to clinical practice for the most appropriate therapy.
Epidemiology and economic impact of amphistomosis in sheep of north-western Himalayas, India
Authors: Sofi Omer Mohi U Din , godara Rajesh , Katoch R. , Yadav A. , Nazim Kaifa , Chakraborty D. 
Published: July 2022

Abstract
Amphistomosis in sheep (n=1210) was examined from November 2020 to October 2021 from north-western Himalayan region of India. This study took into consideration the seasonal prevalence, the intensity of infection and the economic impact of amphistomosis on production parameters of sheep. The overall prevalence was recorded to be 36.3%. Although infection encountered throughout the year, the significantly (p<0.05) higher prevalence was found in monsoon (49.8%) and post-monsoon (42.7%) seasons than winter (31.4%) and summer (25.9%) seasons. Significantly (p<0.05) higher mean egg output (46.5±0.42) was observed in monsoon season followed by summer (27.6±0.41), post-monsoon (22.0 ± 0.17) and winter (12.7±0.42) seasons. Animals aged 6 months to 1 year had significantly higher (p<0.05) prevalence (40.4%) than animals above 1 year (31.6%) and below 6 months (16.9%) of age groups. The total annual economic loss due to amphistomosis in sheep for the study flock was estimated as rupees 462384.0 (US $6188.2) and may be concluded as loss of rupees 1235.0 per animal per annum. Among the various production parameters, reduced body weight contributed the highest in economic loss (95.5%) followed by reduced birth weight of lambs (3.9%) and the least by reduced wool yield (0.6%). Evaluation of the total annual economic recovery by sustainable control of amphistomosis in sheep for the study flock was estimated as rupees 107745.0 (US $1441.9) and may be concluded as recovery of rupees 981.0 per animal per annum. Among the various production parameters, increased body weight contributed the highest in economic recovery (90.1%) followed by increased birth weight of lambs (8.3%) and the least by increased wool yield (1.6%).
Laryngeal leiomyoma: a case report and literature review
Authors: Wu Yu , Yu Tingting , Gao Shengrui , Wang Xin 
Published: July 2022

Abstract

Leiomyomas (LMs) are mesenchymal tumors that derive from smooth muscle cells. Here, we report a rare case of laryngeal leiomyoma (LLM) admitted to our center. We also reviewed and summarized the clinical characteristics of reported LLMs to help clinicians gain a better understanding of this uncommon disease and improve the diagnosis, treatment, and patient postoperative recovery.
Altered regional homogeneity and homotopic connectivity in Chinese breast cancer survivors with fear of cancer recurrence: A Resting-State fMRI Study
Authors: Peng Li , Hu Xiaofei , Xu Chen , Yang Ying , Liu Ju , Chen Jiannan , Qi Aiping , Xue Yuan , Zhong Lin , Li Min 
Published: July 2022

Abstract
Background: Fear of cancer recurrence (FCR) has been one of the most distressing concerns for breast cancer survivors, but the neuroimaging mechanism underlying fear of cancer recurrence still remains unclear. Methods: We recruited 62 breast cancer survivors (31 in the high FCR group and 31 in the low FCR group) to explore the inter-group differences in neuroimaging findings. The data of 3 subjects with low FCR were eliminated because they had not completed all the experiments. All the participants underwent resting-state functional magnetic resonance imaging (rs-fMRI) scan. Regional homogeneity (ReHo) and voxel-mirrored homotopic connectivity (VMHC) methods were applied to analyze the imaging data. Results: Breast cancer survivors with high and low FCR showed significantly different ReHo in the left caudate nucleus and precuneus, and significantly different VMHC in the posterior cerebellar lobe, the superior frontal gyrus, the orbital part, the inferior frontal gyrus, the occipital gyrus, the inferior parietal lobule and the frontal middle gyrus. FCR was negatively correlated with the mean ReHo of left caudate nucleus (r=-0.501, p=0.00004), and positively correlated with the mean ReHo of right precuneus lobe (r=0.505, p=0.000038). Besides, FCR was positively correlated with the mean VMHC value of bilateral superior occipital gyrus (r=0.438, p=0.00051).Conclusion: This study suggested that the left caudate nucleus, right precuneus lobe and bilateral superior occipital gyrus were involved in the neuropathology of FCR.
Effects of Gynostemma pentaphyllum on hypolipidemic and the mechanism of network pharmacology and molecular docking in treating hyperlipidaemia
Authors: Chen Qiuyi , Wu Faming , Zhao Yongxia , Zeng Hongju , Zhong Lin , Men Junpeng , Wu Tao , Liu Xiangpei , Tan Daopeng , He YuQi , Xie Jian 
Published: July 2022

Abstract
Objective: To explore the material basis and potential molecular mechanism of Gynostemma pentaphyllum’s hypolipidaemic effects. Methods: A hyperlipidaemic rat model was established to evaluate the hypolipidaemic effect of Gynostemma pentaphyllum. Next, we verified the bioactive components (BCI) and potential targets of Gynostemma pentaphyllum in the treatment of hyperlipidaemia using network pharmacology and molecular docking, and constructed the pharmacological network and PPI network. Then the core genes were enriched by GO and KEGG. Finally, the bioactive components were docked with the key targets to verify the binding ability between them.Results: The results showed that the serum TC, LDL-C and HDL-C levels were significantly decreased (P<0.05), the number of liver vacuoles was also significantly reduced and the relative expression of PPARγ and SOD mRNA increased (P>0.05) after gynostemma administration. What’s more, a total of 24 active ingredients and 125 common targets of the drug and the disease. PPI network and functional analysis showed that AKT1, TNF, IL6, VEGFA, EGFR, PPARG are very important which were mainly involved in the cancer pathway, the chemo-carcinogenesis-receptor activation pathway, the lipid and atherosclerosis pathway, proteoglycans in cancer, the PI3K-Akt signalling pathway. Molecular docking results showed that the core active components of gibberellin, gibberellin saponin XXVIII, 3'-methylrhodopsin and gibberellin showed good affinity with the Hub gene.Conclusion: Gynostemma has a significant hypolipidaemic effect and may affect lipid metabolism by acting on multiple targets through multiple components.
PIK3CA is recurrently mutated in canine mammary tumors, similarly to in human mammary neoplasia
Authors: Arendt Maja Louise , Sakthikumar Sharadha , Melin Malin , Elvers Ingegerd , Rivera Patricio , Larsen Majbritt , Sällström Sara , Lingaas Frode , Rönnberg Henrik , Lindblad-Toh Kerstin 
Published: July 2022

Abstract
Biological features of neoplastic disease affecting mammary gland tissue are shared between canines and humans. Research performed in either species has translational value and early phase clinical trials performed in canines with spontaneous disease could be informative for human trials. The purpose of this study was to investigate the somatic genetic aberrations occurring in canine mammary neoplasia by exome capture and next generation sequencing. Based on 57 tumor-normal pairs we identified the PIK3CA gene as the most commonly mutated gene in canine mammary tumors, with 25% of samples carrying mutations in this gene. A recurrent missense mutation was identified p.H1047R, which is homologous to the human PIK3CA hotspot mutation found in different types of breast neoplasia. Mutations homologous to other known human mutation hotspots such as the PIK3CA p.E545K and the KRAS p.G12V/D were also identified. We identified copy number aberrations affecting important tumor suppressor and oncogenic pathways including deletions affecting the PTEN tumor suppressor gene. We show evidence that activation of the KRAS or PIK3CA oncogenes or loss of the PTEN suppressor gene are important for mammary tumor development in dogs. This data endorses the conservation of cancer across species and the validity of studying cancer in other species.
Changes in sexual behavior among men who have sex with men during the spread of COVID-19 in China: results of an online survey
Authors: Lyu Hang , Zhen Shihan , Feng Yunlong , Huang Shanzi , Li Jiarun , Zhou Yi , Tang Weiming 
Published: July 2022

Abstract
Background: Sexual behavior drives the transmission of sexually transmitted infections, especially among men who have sex with men (MSM). This study aims to evaluate the sexual behavior changed among MSM during the outbreak of COVID-19.Material and Methods: An online survey was conducted to collect sociodemographic, sexual behavioral, and HIV testing information before and during the COVID-19 epidemic. Chi-square was used to determine the behavior differences before and during the COVID-19 pandemic. We identified the factors associated with casual sexual behavior among MSM using bivariate and multivariable logistic regression.Results: A total of 506 MSM participated in the online survey. The 506 MSM were individuals born biologically as a male, self-identified as a male, aged 18 or over, and ever engaged in sex with a man (in the past three month). Compared with participants who didn't reduce the number of sexual partners (n = 193, 38.1%), participants who reduced sexual partners (n = 313, 61.9%) had higher values of multiple sexual partners, causal sexual partners, used a condom with causal sexual partners, and sought sexual partners using apps (all p< 0.05). Participants who reduced the number of sexual partners than before COVID-19, reported having a higher proportion of causal sexual behavior (66.77% vs 46.11%, c2 = 21.047, p< 0.001), which means engaged in casual sex in the last three months. But at-risk sexual behavior, which means unprotected anal sex with a casual partner without using condom protection, did not change significantly between the two groups during COVID-19 (p>0.05). Multiple factors are related to casual sexual behavior and at-risk sexual behavior.Conclusions: During the COVID-19 pandemic, the lockdown measures significantly impacted the sexual behavior of Chinese MSM. Sustain behavior interventions are still needed during the COVID-19 pandemic.
Effects of ash composition and combustion temperature on reduced particulate matter emission by biomass carbonization
Authors: Dalkhsuren Davaajav , Iwabuchi Kazunori , Itoh Takanori , Takumi Narita , Piash Mahmudul Islam , Nachin Baatarbileg , Sukhbaatar Gerelbaatar 
Published: July 2022

Abstract
Biomass is a potential substitute for fossil fuels but has some drawbacks, such as low energy density, high moisture content, and particulate matter (PM) emissions during combustion, that need to be addressed. Thermochemical pretreatment, including carbonization, has been suggested to address these issues. However, the efficiency of carbonization is not equal for all types of biomass due to composition heterogeneity. Therefore, this study involved the carbonization of seven types of biomass (larch, poplar, miscanthus, bamboo grass, rice straw, rice husk, and dairy manure) at 400°C to evaluate efficiency in enhancing fuel properties and reducing PM emissions. All raw and carbonized samples were combusted at 650, 750, and 850°C to assess the effect of combustion temperature on PM emission. Results showed that PM emission was greatly reduced up to 95.45% after carbonization via volatile matter removal. The efficiency of PM reduction was greatest at low burning temperatures for all feedstocks. Although combustion temperatures had no major impact on PM emissions from low-ash (≤ 6.6%) biomass, higher heating temperatures (750°C or above) stimulated PM emissions from ash-rich rice straw and dairy manure biochar. The transformation of minerals in rice straw, rice husk, and dairy manure also was investigated at different combustion temperatures (650, 750, and 850°C). Data revealed that enhanced PM emission from ash-rich biochar samples was due to a greater concentration of Na and K, likely through Na and K melting at higher temperatures. Therefore, to limit PM emissions from the chars produced by high-alkali-metal biomass, a lower combustion temperature is preferable.