bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE MORPHOLOGICAL ADAPTATION OF HEART STRUCTURES AND BIOCHEMICAL BLOOD PARAMETERS OF ROSS-308 BROILER CHICKENS WHEN INTRODUCING THE «KOVELOS-SORB» SORBENT INTO THE MAIN DIET
Authors: Novtseva Evgenia Yu. , Zaitseva Elena V. , Kharlan Alexey L. 
Published: October 2022

Background. Currently, the poultry industry is developing quite intensively, this is why the use of various additives that accelerate growth and improve the quality of products is associated with this. The biologically active additive «Kovelos-Sorb» has similar properties – an enterosorbent based on particles of amorphous silicon dioxide.
Purpose. To study the features of morphological adaptation of heart structures and biochemical blood parameters of Ross-308 broiler chickens when introducing the «Kovelos-Sorb» sorbent into the main diet.
Materials and methods. Two groups of Ross-308 broiler chickens were studied from 1 day to 40 days, with a total number of 160 heads from 8 age groups of 10 individuals each. The experimental group of chickens was injected with the sorbent «Kovelos-Sorb» in the amount of 0.1% by weight of feed to the main diet. The study of morphological and biochemical parameters of the broiler organism was carried out according to generally accepted methods.
Results. The analysis of the dynamics of changes in the morphological structures of the heart (linear measurements – longitudinal size, transverse size, girth, thickness of the epicardium, myocardium, endocardium, thickness of muscle fibers), the volume of cardiomyocyte nuclei, biochemical blood parameters of Ross-308 broiler chickens when added to the main diet of the enterosorbent «Kovelos-Sorb».
Conclusion. It was found that the silicon-containing sorbent «Kovelos-Sorb» has a positive effect on the qualitative morphological characteristics of the heart of Ross-308 broiler chickens, manifested by stabilization of shell structures, in an increase in the thickness of the muscle fibers of the atria and ventricles of the heart.
TIME PERSPECTIVE IN THE CONTEXT OF THE PROBLEM OF PSYCHOLOGICAL HEALTH OF MILITARY UNIVERSITY CADETS
Authors: Yanitsky Mikhail S. , Utyuganov Alexey A. , Yumatov Vitaly A. , Ivanov Mihail S. , Frolova Larisa V. , Mukhina Anastasia D. 
Published: October 2022

Background. The time perspective of the individual acts as an indicator of the psychological health of cadets and is considered from the standpoint of optimizing health-saving technologies in military education. The dynamics of the time perspective of the personality of cadets of the University of the National Guard troops of the Russian Federation at different stages of training is analyzed.
Materials and methods. As methods of collecting empirical data, the method “Semantic time differential” by L.I. Wasserman et al., the method “Time Perspective Questionnaire” (ZTPI) by F. Zimbardo were used. The method of statistical comparative analysis using the Student’s T-test was used for quantitative data analysis. In total, 198 cadets of 1-5 courses of the Novosibirsk Military Institute named after General of the Army I.K. Yakovlev of the National Guard troops took part in the study.
Results. The study shows a significant difference in the indicators of the time perspective of cadets of a military university with normative values, and in some indicators the cadets significantly exceed the normative values, and in some they do not correspond. It is also shown that there are statistically significant differences in the characteristics of the time perspective between cadets at different stages of training, which indicates the dynamics of the indicators of the time perspective.
Conclusion. It is concluded that there are problems with the cadets’ time perspective, which consist in insufficient awareness of the present, insufficient activity in experiencing time and low perceptibility of time at the initial stages of training. It is assumed that the compensatory mechanisms that ensure the preservation of psychological health are increased emotionality in the perception of time.
MEDICAL EFFICACY OF A SPONTANEOUS MEDICO-SOCIAL EXPERIMENT (BY THE EXAMPLE OF COVID-19 REGIONAL PREVENTION)
Authors: Khudonogov Igor Yu. , Kremen Evgeny V. , Kremen Svetlana V. , Koloskova Tatyana A. 
Published: October 2022

Relevance: studies of the effectiveness of large-scale medico-social experiments (MSE) are quite rare. On the one hand, MSE is, as a rule, a response to force majeure circumstances, which should not be at all in ordinary live. On the other hand, such experiments, as well as their study, are processes characterized by high cost and considerable duration. Nevertheless, the example of COVID-19 regional prevention shows that coordinated interaction of various parts of the social organism can and should be carried out in a critical situation, that the effectiveness of this interaction should be quantified using integrative indicators of sanitary statistics. This interaction illustrates the spontaneous formation of a regional model of preventive healthcare of the future, which is characterized by active socio-economic and information-cognitive support of the main preventive and (or) treatment and diagnostic process aimed at the population of the region using a wide range of activities, including traditional and new educational technologies.
Gol: to evaluate the medical effectiveness of the first pre-vaccination year of COVID-19 prevention at the regional level using integrative quantitative indicators of sanitary statistics.
Methods: historical, statistical, graphical, linear regression analysis, system analysis and synthesis, organizational and methodological modeling.
Results: the slope coefficients in the linear regression formulas corresponding to the annual growth rate (GR) on the graphs of prevalence and incidence in the studied social groups indicated that in the pre-pandemic years, the prevalence in the population was permanently growing - GR was within from +17 to +49 ‰ per year, and the incidence showed relative stability - GR was in the range from +8 to +12 ‰, and even decreased in the children’s population (-17 ‰ annually). Comprehensive preventive measures of the first pandemic year (2020) reversed the general growth trend and accelerated the process significantly. Thus, incidence GR was in the range from -35 to -257 ‰, and prevalence GR - from -179 to -326 ‰.
Conclusion: preventive measures against COVID-19, carried out in the form of a large-scale MSE, made it possible to introduce at the regional level a model of systemic integrated preventive healthcare of the future, the medical effectiveness of which is many times greater than the previous organizational and methodological model of “autonomous” healthcare, as far as this can be judged by the emerging trends of change integrative indicators of health (prevalence and incidence).
NUTRIENTS CONTENT IN FRUITS OF VARIETIES AND HYBRIDS OF GUELDER ROSE (VIBURNUM OPULUS L.) IN CONDITIONS OF THE WESTERN SIBERIAN SOUTH
Authors: Borodulina Irina D. , Ershova Inessa V. 
Published: October 2022

Guelder rose (V. opulus L., 1753) is a rare garden crop widespread throughout Russia. It is a valuable food and medicinal raw material due to its rich chemical composition. It contains biologically active phenolic compounds, pectin substances, triterpenoids, polysaccharides, carbohydrates, organic acids, and macro- and micro-elements.
The study aimed to investigate the content and variability of soluble solids (SS) and sugars in fruits of V. opulus L. in the conditions of the South of Western Siberia. The research objects are fruits of V. opulus L. of 2 varieties (Taezhnye Rubiny and Avrora) and 15 hybrids. The authors employ the Taezhnye Rubiny variety as a control.
The SS content has been determined by the refractometric method and the mass content of sugars – by direct titration of an aqueous extract. The authors calculate Selyaninov’s hydrothermal coefficient (HTC) to characterize the growing season. The limits are determined for the accumulation of SS (from 10.2% to 18.2%) and sugars (from 7.3% to 10.0%) and the variability of these features (14% and 10%, respectively).
The number of genotypes with a stable accumulation of SS identified over the years is 82%, and that with high sugar content (8.6%–10.0%) is 35%. The analysis reveals an average adverse correlation between HTC and the accumulation of SS (r=-0.62) and sugars (r=-0.34) in fruits and a strong dependence of these biochemical features on HTC in control (r=0.93, r=0.95).
BLOOD MINERAL PROFILE IN NEWBORN CALVES WITH INTRAUTERINE GROWTH RETARDATION
Authors: Chernitskiy Anton E. , Tatiana S. Ermilova Tatiana S. , Salimzade Emil A.O. , Safonov Vladimir A. 
Published: October 2022

Widespread intrauterine growth retardation of embryo and fetal (IUGR) in cattle and its negative effects on postnatal growth and offspring health threaten the economic sustainability of livestock production. IUGR calves often exhibit birth weight deficits, early death, metabolic abnormalities, low growth rate, and poor feed utilization. Effective correction of these disorders is impossible without a detailed study of the causes, mechanisms of development and consequences of IUGR. In the present work, a comparative analysis of the content of macrominerals and trace elements in the blood of newborn Simmental calves with IUGR (Group I, n = 20) and the physiological course of pregnancy in their mothers (Group II, n = 20) was carried out. Blood for studies in calves was obtained at 1 day of age, before the 4th feeding of colostrum. The content of sodium, potassium, calcium and magnesium in blood serum samples and the content of iron, copper, zinc, manganese, cobalt and selenium in whole blood samples were studied by atomic absorption spectrometry (AA6300, Shimadzu, Japan). Group I calves had increased serum potassium (by 6.7%, P = 0.022) and magnesium (by 6.3%, P = 0.004) and decreased sodium (by 4.3%, P = 0. 005), reduced whole blood selenium (by 41.0%, P = 0.0001), copper (by 23.6%, P = 0.0001), and manganese (by 23.4%, P = 0.005) compared with Group II animals. The blood content of the other minerals studied did not differ significantly between the groups. The possible causes and consequences of the identified disorders of the mineral blood profile in newborn calves with IUGR were analyzed.
Altered microvasculature in pancreatic islets from subjects with type 1 diabetes
Authors: Granlund Louise , Hedin Anders , Korsgren Olle , Skog Oskar , Lundberg Marcus 
Published: October 2022

Aims
The transcriptome of different dissociated pancreatic islet cells has been described in enzymatically isolated islets in both health and disease. However, the isolation, culturing, and dissociation procedures likely affect the transcriptome profiles, distorting the biological conclusions. The aim of the current study was to characterize the cells of the islets of Langerhans from subjects with and without type 1 diabetes in a way that reflects the in vivo situation to the highest possible extent.

Methods
Islets were excised using laser capture microdissection directly from frozen pancreatic tissue sections obtained from organ donors with (n = 7) and without (n = 8) type 1 diabetes. Transcriptome analysis of excised samples was performed using AmpliSeq. Consecutive pancreatic sections were used to estimate the proportion of beta-, alpha-, and delta cells using immunofluorescence and to examine the presence of CD31 positive endothelial regions using immunohistochemistry.

Results
The proportion of beta cells in islets from subjects with type 1 diabetes was reduced to 0% according to both the histological and transcriptome data, and several alterations in the transcriptome were derived from the loss of beta cells. In total, 473 differentially expressed genes were found in the islets from subjects with type 1 diabetes. Functional enrichment analysis showed that several of the most upregulated gene sets were related to vasculature and angiogenesis, and histologically, vascular density was increased in subjects with type 1 diabetes. Downregulated in type 1 diabetes islets was the gene set epithelial mesenchymal transition.

Conclusion
A number of transcriptional alterations are present in islets from subjects with type 1 diabetes. In particular, several gene sets related to vasculature and angiogenesis are upregulated and there is an increased vascular density, suggesting an altered microvasculature in islets from subjects with type 1 diabetes. By studying pancreatic islets extracted directly from snap-frozen pancreatic tissue, this study reflects the in vivo situation to a high degree and gives important insights into islet pathophysiology in type 1 diabetes.
Pengembangan Buku Pengayaan Kewirausahaan Materi Aspek Biokimia Hasil Pengolahan Crude Palm Oil (CPO) Untuk Siswa SMA/MA
Authors: Aisyah Siti 
Published: October 2022

Kewirausahaan merupakan aspek penting yang harus dimiliki lulusan SMA agar mengurangi jumlah pengangguran di Indonesia. Penelitian ini bertujuan untuk mengembangkan buku pengayaan kewirausahaan materi aspek biokimia hasil pengolahan Crude Palm Oil (CPO). Penelitian ini merupakan penelitian pengembangan (R&D) dengan model pengembangan 4D yang terdiri atas tahap define, design, develop, dan disseminate. Produk divalidasi dan dinilai oleh satu dosen ahli materi, satu dosen ahli media, tiga guru SMA, serta direspon oleh sepuluh siswa SMA. Penilaian kualitas produk dilakukan menggunakan lembar angket skala Likert, sedangkan respon siswa dilakukan menggunakan lembar angket skala Guttman. Hasil penilaian kualitas produk oleh ahli materi mendapatkan persentase 93,33% dengan kategori Sangat Baik (SB), penilaian produk oleh ahli media mendapatkan persentase 80,00% dengan kategori Baik (B), dan penilaian produk oleh guru SMA mendapatkan persentase 81,73% dengan kategori Sangat Baik (SB). Produk direspon positif oleh siswa dengan persentase sebesar 89% sehingga buku pengayaan yang dikembangkan dapat digunakan dalam proses pembelajaran untuk meningkatkan kewirausahaan siswa SMA pada pengolahan Crude Palm Oil (CPO)
Changes in body composition and blood parameters in sedentary women during 12 weeks of complex exercises
Authors: Apaydın Murat B. , Polat Metin 
Published: October 2022

Background and Study Aim. There are studies examining the effects of exercise programs on body and blood parameters in sedentary individuals, but there are few studies examining the effects of resistance and cardio exercises in combination. The aim of this study was to investigate the effects of step-aerobic, cardio and resistance training on body composition and blood parameters in sedentary women for 12 weeks.
Material and Methods. Step- Aerobic, Cardio and Resistance exercises were applied to the volunteers participating in the study for 12 weeks, 3 days a week for 1 hour each. Body weight, body mass index, body fat percentage and body muscle percentage values were determined from body composition measurements before and after the application. Glucose, Vitamin D3, Triglyceride, Cholesterol, High-density lipoprotein and Low-density values were measured from blood parameters. There is no exercise planning was done in the control group.
Results. After the exercise program, a significant decrease (p<0.05) in body weight, body mass index, body fat ratio, Glucose, Vitamin D3, Triglyceride, Cholesterol and Low-density values and a significant increase (p<0.05) in High-density lipoprotein and values were determined in the study group. In the control group, no significant change was observed in both body composition and blood parameters (p>0.05).
Conclusions. In the this study, it was found resistance, cardio and step-aerobic exercise programs had a positive effect on body composition and blood parameters in sedentary women. In the control group, there is no positive data for the end of the this study and there is no significant change not only body parametres bu also blood measurement in the control group.
Perceived barriers to adopting information and communication technology in physical education
Authors: Irwahand Fathin Nurul Ezzati , Mat-Rasid Siti Musliha , Lee Jeffrey Low Fok , Elumalai Gunathevan , Shahril Mohd Izwan , Ahmad Mohamad Azri Ismail 
Published: October 2022

Background and Study Aim. The use of Information and Communication Technologies (ICTs) in Physical Education (PE) brings the science of sports to life by combining physical and mental activity. It also helps students focus better on practical and theoretical work. The purpose of this study was to investigate the perceived barriers to adopting ICTs in PE lessons among high school teachers in Malaysia.
Material and Methods. A total of 112 Physical Education teachers were selected by stratified random sampling to answer an online questionnaire. Cluster analysis was then conducted to classify PE teachers’ profiles according to the frequency scores of experiencing challenges in using ICT tools in PE teaching and learning. Discriminant analyses were performed to determine the significant barriers related to technology that differentiate these clusters.
Results. In conclusion, Cluster analysis identified three well-defined profiles: cluster 1 (excellent degrees in applying ICT to their teaching practices) consists of 44 teachers; cluster 2 (moderate degrees in applying ICT to their teaching practices) consist of 41 teachers; cluster 3 (poor degrees in applying ICT to their teaching practices) consist of 27 teachers. Results revealed seven out of twelve technology-related barriers were significant among these clusters. They are the insufficient number of computers (p<0.001), insufficient number of internet‐connected computers (p<0.001), insufficient pedagogical support for teachers (p<0.001), lack of content in the national language (p<0.001), pressure to prepare students for exams and tests (p<0.001), no or unclear benefit to using ICT for teaching (p<0.001) and perception of using ICT in teaching and learning not being a goal in their school (p<0.001).
Conclusions. Awareness of these barriers has implications for physical education, curriculum design, teacher training, and youth participation in the school environment. The positive opinions and attitudes of PE teachers toward ICTs as educational tools could pave the way for improving their digital literacy. Thus increase their rate of use of these tools if they are provided with the appropriate technical resources and training.
Design and validation of a questionnaire to assess the Pedagogical Content Knowledge of Colombian Physical Education students in the practicum
Authors: Montoya Noelva E. , Almonacid-Fierro Alejandro A. , Arroyave Giraldo Dora I. , Valdebenito González Karla B. 
Published: October 2022

Background and Study Aim. In the training of Physical Education teachers, the practicum is considered a final stage of the training. The practicum implies an amalgamation and connection of the different knowledge acquired at the University and that, when contrasted with the real classroom practice, plays a fundamental role in the future professional development. The purpose of this study was to design and validate a questionnaire to measure the Pedagogical Content Knowledge of the Physical Education teacher trainee in the context of the practicum.
Material and Methods. The participants were 146 practicum students of the Bachelor's degree program in Physical Education from four Colombian universities (115 men, 31 women, with an average age of 25.7 + 5.2 years). A non-experimental descriptive cross-sectional study was conducted in two phases, the first one: content validity and the second phase related to the analysis of psychometric properties.
Results. A Content Validity Ratio of .92 was presented, which indicates a very high content validity based on Lawshe's model and with a sample of 10 expert judges in the field. In the exploratory factor analysis by the principal component analysis method and varimax rotation, 7 dimensions were proposed, with 36 items explaining 66.78 of the total variance of the instrument. The internal consistency was very satisfactory (α=.9).
Conclusions. The questionnaire provides a valid, trustable, and specific instrument, which allows identifying the knowledge that a Physical Education practice student has about pedagogy, context, evaluation, teaching strategies, students, experience, and content. Furthermore, understanding this type of knowledge is a precondition that can allow improving the curricular designs of Physical Education degree programs.
The effectiveness of using power fitness training loads to increase adaptive reserves of female athletes in hand-to-hand combat
Authors: Manolachi Veaceslav , Chernozub Andrii , Potop Vladimir , Marionda Ivan , Titova Hanna , Sherstiuk Liudmyla , Shtefiuk Ivan 
Published: October 2022

Background and Study Purpose. One of the main aspects of improving the special training of athletes in hand-to-hand combat is increasing functional reserves in conditions of power loads. Study Purpose - to study the peculiarities of adaptive body changes and the level of special training in female athletes of hand-to-hand combat using power fitness programs with different structure, parameters, and means.
Material and Methods. We examined 36 female athletes (18-20 years old) who had been engaged in hand-to-hand combat for the last 4 years. We divided these women into two groups,18 people in each group. Groups used completely different power fitness training programs. We used methods of testing special training (the number of accurate kicks on the mannequin for 30 s) and laboratory monitoring of blood biochemical parameters (cortisol and LDH) before and after training load during 3 months. Group A used the standard power fitness training program for women of this age (exercises on simulators). Group B used well-known exercises with their own body weight with a complete change of kinematic and dynamic characteristics of the technique during 3 months of training.
Results. The obtained results showed that indicators of special training positively changed by 10.4% (p <0.05) in group B athletes. At the same time, the studied indicator increased by 2.2% compared to initial level in group A athletes. At the end of the study, we observed an increase in cortisol level in the blood serum of group B athletes in response to physical stimuli. This was almost 10 times lower than the results recorded in group A. The results of monitoring LDH activity in the blood serum showed that its level increased by 19.5% (p <0.05) during the entire study period only in group B athletes. The controlled indicator remained almost unchanged in group A. The dynamics of the studied steroid hormone and enzyme in the blood serum in group B indicated an increase in the level of organism resistance to training loads under specified conditions of muscular activity and their pronounced adaptive changes.
Conclusions. Determining the most effective power fitness training program for special training of female athletes in hand-to-hand combat, will help to increase their adaptive body reserves and their level of fitness. For this using different in structure and parameters training load.