bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estado de humor e a tolerância ao risco em decisões organizacionais
Authors: Zacchi Mateus , Fagundes Ernando , Rengel Rodrigo , Adamczyk Willian Boschetti 
Published: April 2022

Objective of the study: This study aims to identify the relationship between an individual's mood and risk tolerance in organizational decisions.Methodology/approach: It is an applied, quantitative, descriptive and survey research. For data collection, a questionnaire was applied to a sample of 90 academics from higher education courses in the area of management at a Higher Education Institution in the State of Santa Catarina. Data were categorized and analyzed quantitatively using descriptive statistics, correlation analysis and logistic regression analysis.Originality/relevance: Researches relate positive mood and increased risk-taking, however, the results are fragmented and inconclusive as to the influence of negative mood on the tendency to take risks. Thus, this research focuses attention on the asymmetry of influence of both positive and negative mood on risk preferences.Main results: We found that in decisions involving gains, respondents have less tolerance than when they involve losses. Although mood is not related to risk tolerance, when analyzed separately, a relationship was found between the dimensions of mood and the individuals' risk tolerance.Theoretical/methodological contributions: This research adds to the literature, by exploring decision-making and the behavioral line simultaneously, as well as contributing to represent a more comprehensive description regarding the decision process regarding the Prospect Theory, by demonstrating which dimensions of mood have an influence on the risk tolerance of respondents.Social/management contributions: The study contributes to the improvement of decision-making processes in the context of aspects related to risk tolerance. The practical implications refer to the construction of a decision-making process designed in a more assertive way and in line with the losses and gains arising from the inherent risk of this decision-making process.
V. AML smernica – aplikačné problémy súvisiace s reguláciou virtuálnych mien
Authors: Daudrikh Yana 
Published: April 2022

Primárny regulačný rámec obchodovania s virtuálnymi menami je upravený v V. AML smernici. Ide zrejme o najproblematickejšiu oblasť boja proti legalizácii príjmov z trestnej činnosti a financovania terorizmu, vzhľadom k hybridnej povahe virtuálnych mien. Nejednotnosť názorov na reguláciu virtuálnych mien badať aj na medzinárodnej úrovni. Viaceré medzinárodné inštitúcie vyčítajú V. AML smernici nedostatočnosť a problematickosť aplikácie definície pojmu virtuálna mena a zoznamu povinných osôb. V tejto súvislosti poskytneme bližšiu analýzu právnej povahy virtuálnej meny a rovnako tak sa pokúsime o priblíženie svojich úvah a postojov k právnej úprave de lege lata a de lege ferenda.
Factors Relating to the Expectations and Perceptions of Post-Stroke Outpatients’ in the Rehabilitation Services of Bangladesh
Authors: Hasan Mohammad Shaikhul , Anusaksathien Kantabhat , Narattharaksa Kanida , Afrin Nahar 
Published: April 2022

Purpose: For enhancing patients’ participation, this study aims to identify the patient-related factors that relate to the expectations and perceptions of post-stroke outpatients’ in the rehabilitation services of Bangladesh.
Methods: A questionnaire survey was administered to 342 outpatients from the stroke rehabilitation department. Descriptive statistical analysis was applied to measure patients’ perceptions and expectations. Eta statistic from ANOVA was applied to examine the relationship between patient-related factors and the patients’ expectations and perceptions of the rehabilitation services.
Findings: Patients’ expectations rated higher than the perceptions in all the dimensions of rehabilitation services. Factors such as; (i) patients' education (0.222, p=0.005) and post-stroke disability (0.447, p<0.001) indicated a significant relationship with patients' expectations. (ii) Patients' education (0.210, p=0.010), occupation (0.226, p=0.003), family status (0.180, p=0.048) and daily activities before the stroke (0.169, p=0.044), post-stroke disability (0.195, p=0.004) and distance from home to the hospital (0.190, p=0.006) indicated a significant relationship with their perceptions in the rehabilitation services.
Conclusion: The findings of this study concluded that the rehabilitation manager needs to work on these factors and recommended developing a continuing education program to minimize these factors of poor perceptions in the rehabilitation services.
Design after Capitalism
Authors: Wizinsky Matthew 
Published: April 2022

How design can transcend the logics, structures, and subjectivities of capitalism: a framework, theoretical grounding, and practical principles.
The designed things, experiences, and symbols that we use to perceive, understand, and perform our everyday lives are much more than just props. They directly shape how we live. In Design after Capitalism, Matthew Wizinsky argues that the world of industrial capitalism that gave birth to modern design has been dramatically transformed. Design today needs to reorient itself toward deliberate transitions of everyday politics, social relations, and economies. Looking at design through the lens of political economy, Wizinsky calls for the field to transcend the logics, structures, and subjectivities of capitalism—to combine design entrepreneurship with social empowerment in order to facilitate new ways of producing those things, symbols, and experiences that make up everyday life.
After analyzing the parallel histories of capitalism and design, Wizinsky offers some historical examples of anticapitalist, noncapitalist, and postcapitalist models of design practice. These range from the British Arts and Crafts movement of the nineteenth century to contemporary practices of growing furniture or biotextiles and automated forms of production. Drawing on insights from sociology, philosophy, economics, political science, history, environmental and sustainability studies, and critical theory—fields not usually seen as central to design—he lays out core principles for postcapitalist design; offers strategies for applying these principles to the three layers of project, practice, and discipline; and provides a set of practical guidelines for designers to use as a starting point. The work of postcapitalist design can start today, Wizinsky says—with the next project.
Activación de la microglía en el hipocampo asociada con lesión del nervio facial
Authors: Cerón Jeimmy , Troncoso Julieta 
Published: April 2022

Introducción. Las lesiones del nervio facial afectan la plasticidad a largo plazo en el hipocampo, así como la memoria de reconocimiento de objetos y la memoria espacial, dos procesos dependientes de esta estructura. Objetivo. Caracterizar en ratas el efecto de la lesión unilateral del nervio facial sobre la activación de células de la microglía en el hipocampo contralateral.Materiales y métodos. Se hicieron experimentos de inmunohistoquímica para detectar células de la microglía en el hipocampo de ratas sometidas a lesión irreversible del nervio facial. Los animales se sacrificaron en distintos momentos después de la lesión, para evaluar la evolución de la proliferación (densidad de células) y la activación (área celular) de la microglía en el tejido del hipocampo. Los tejidos cerebrales de los animales de control se compararon con los de animales lesionados sacrificados en los días 1, 3, 7, 21 y 35 después de la lesión.Resultados. Las células de la microglía en el hipocampo de animales con lesión del nervio facial mostraron signos de proliferación y activación a los 3, 7 y 21 días después de la lesión. Sin embargo, al cabo de cinco semanas, estas modificaciones se revirtieron, a pesar de que no hubo recuperación funcional de la parálisis facial.Conclusiones. La lesión irreversible del nervio facial produce proliferación y activación temprana y transitoria de las células de la microglía en el hipocampo. Estos cambios podrían estar asociados con las modificaciones electrofisiológicas y las alteraciones comportamentales dependientes del hipocampo descritas recientemente.
A Multi‐Scale Approach for Modeling the Optical Response of Molecular Materials Inside Cavities
Authors: Zerulla Benedikt , Krstić Marjan , Beutel Dominik , Holzer Christof , Wöll Christof , Rockstuhl Carsten , Fernandez‐Corbaton Ivan 
Published: April 2022

AbstractThe recent fabrication advances in nanoscience and molecular materials point toward a new era where material properties are tailored in silico for target applications. To fully realize this potential, accurate and computationally efficient theoretical models are needed for: a) the computer‐aided design and optimization of new materials before their fabrication; and b) the accurate interpretation of experiments. The development of such theoretical models is a challenging multi‐disciplinary problem where physics, chemistry, and material science are intertwined across spatial scales ranging from the molecular to the device level, that is, from ångströms to millimeters. In photonic applications, molecular materials are often placed inside optical cavities. Together with the sought‐after enhancement of light‐molecule interactions, the cavities bring additional complexity to the modeling of such devices. Here, a multi‐scale approach that, starting from ab initio quantum mechanical molecular simulations, can compute the electromagnetic response of macroscopic devices such as cavities containing molecular materials is presented. Molecular time‐dependent density‐functional theory calculations are combined with the efficient transition matrix based solution of Maxwell's equations. Some of the capabilities of the approach are demonstrated by simulating surface metal‐organic frameworks ‐in‐cavity and J‐aggregates‐in‐cavity systems that have been recently investigated experimentally, and providing a refined understanding of the experimental results.
Terahertz Metagrating Accordion for Dynamic Beam Steering
Authors: Cheng Jierong , Dong Xipu , Chen Sai , Yuan Yiwu , Wen Qiye , Chang Shengjiang 
Published: April 2022

AbstractMetasurfaces can be used to manipulate the beam direction beyond the Snell's law by the constitutive gradient elements. Independent control of the phase response of each element is usually required for real‐time beam steering, which is very challenging at terahertz (THz) frequencies. Here a type of accordion‐shaped single‐element metagratings for THz beam scanning and angle‐adaptive retroreflection is proposed. The metagrating is carefully designed to enhance the +1st order diffraction while suppressing other orders for efficient beam steering. Benefiting from the periodic arrangement, dynamic beam steering is realized by imparting desired momentum via mechanical compression and rotation, instead of the complicated element‐by‐element modulation. Beam scanning in a plane and over the 3D space is experimentally validated with elevation angles from 45° to 75° and azimuthal angles over 360°. An angle‐adaptive retroreflector by adding a metallic plate to the metagrating is studied with near perfect theoretical diffraction efficiency for incident angles within 40°–85°. The physical mechanism of wide‐angle high efficiency is detailed by the mode analysis, and can be generalized into other frequencies. The study here may find applications in THz communications and radar detections, and open a new avenue to facilitate reconfigurable metadevices for wavefront modulation.
Excited‐State‐Modulated Dual‐Wavelength Single‐Mode Lasing from a Single‐Component Organic Microbelt
Authors: De Jianbo , Liu Zhenzhi , Yin Fan , Chen Jingyao , Gu Chunling , Liu Huiying , Liu Fu , Geng Hua , Fu Hongbing , Liao Qing 
Published: April 2022

AbstractSingle‐mode laser is of fundamental importance due to its beam quality and spectral purity. However, common lasers operate in multimode as the dimensions of most laser resonators are much larger than the operating wavelengths. Herein, the novel dual‐wavelength single‐mode lasing from a solution of self‐assembled single‐component microbelt that consists of excited‐state intramolecular proton transfer molecules is demonstrated. The large modulation of the gain regimes and the cooperative effect between gain and loss in the cavity are proven experimentally and theoretically to be effective strategies for achieving multiple‐wavelength and single‐mode operation. These results broaden optical science and provide new insight into the construction of multicolor lasers with high spectral purity for the on‐chip integrated photonic system.
Quasi‐1D Antiferroelectricity in Centrosymmetric CsTaS3 Crystal
Authors: Bie Jie , Zhou Jian , Fa Wei 
Published: April 2022

Abstract1D ferroelectric (FE) materials are expected to be promising low‐dimensional materials for nanometer devices, but are rarely reported. The previous experiment discovered that quasi‐1D CsTaS3 crystalizes in centrosymmetric space group, but in which the Ta cations have a strange shift along the c axis from the center of TaS6 octahedron. Here, the crystal structure, electronic structure, ferroelectric, and piezoelectric properties of CsTaS3 by using first‐principles calculations are studied. It is found that the empty d orbitals of Ta cations induce the distortions of TaS6 octahedra, which bring the polarity along a given [TaS3]− chain. The adjacent chains are antiferroelectric (AFE) coupling making CsTaS3 being an AFE material. However, the FE phase of CsTaS3 is supposed to be accessible since its total energy is only 0.3 meV per formula higher than that of the AFE phase. The polarization of FE CsTaS3 is estimated to be 16.8 μC cm−2, which is comparable to those of well‐known FE perovskites. The work predicts a quasi‐1D AFE material, which would be helpful for subsequent experimental work.
Analysis of competing endogenous RNA (ceRNA) crosstalk in eosinophilic chronic rhinosinusitis with nasal polyps
Authors: Li Ke , Liu Fang‐Fang 
Published: April 2022

AbstractBackgroundChronic rhinosinusitis with nasal polyps (CRSwNP) is one of the most common chronic inflammatory diseases, and has various phenotypes. Although its pathophysiology remains obscure, evidence has shown that dysregulation of noncoding RNAs (ncRNAs) is associated with CRSwNP. ncRNAs in the cytoplasm can act as competing endogenous RNAs (ceRNAs), which are involved in many inflammatory processes. However, the ceRNA crosstalk in CRSwNP is still unclearMethodsWe investigated expression profiles of messenger RNA (mRNA), microRNAs (miRNAs), and long noncoding RNAs (lncRNAs) in eosinophilic CRSwNP and constructed a global triple ceRNA network.ResultsAs a result, 964 differentially expressed mRNAs (DEmRs), 207 differentially expressed miRNAs (DEmiRs), and 15 differentially expressed lncRNAs (DElncRs) were identified, and a ceRNA network containing 598 miRNA‐mRNA pairs and 70 lncRNA‐miRNA pairs was finally constructed. Gene set enrichment analysis (GSEA) results indicated these DEmRs were mainly enriched in “cytokine‐cytokine receptor interaction,” “salivary secretion,” “hematopoietic cell lineage,” and “chemokine signaling pathway.” Moreover, we also predicted the subcellular localization of the DElncRs identified in the network via bioinformatics approaches ConclusionIn summary, the present study provided the first comprehensive assessment of the ceRNA crosstalk in eosinophilic CRSwNP. These findings will be of interest to the understanding of the potential pathophysiology of this disease.
Cobalt/Salox‐Catalyzed Enantioselective C−H Functionalization of Arylphosphinamides
Authors: Yao Qi‐Jun , Chen Jia‐Hao , Song Hong , Huang Fan‐Rui , Shi Bing‐Feng 
Published: April 2022

AbstractPrevious methods on CoIII‐catalyzed asymmetric C−H activation rely on the use of tailor‐made cyclopentadienyl‐ligated CoIII complexes, which require lengthy steps for the preparation. Herein, we report an unprecedented enantioselective C−H functionalization enabled by a simple cobalt/salicyloxazoline (Salox) catalysis. The chiral Salox ligands can be easily prepared in one step from salicylonitrile and chiral amino alcohols. A broad range of P‐stereogenic compounds were synthesized in high yields with excellent enantioselectivities (45 examples, up to 99 % yield and >99 % ee). The isolation and characterization of several intermediates provided insights into the generation of active catalytic cobalt species, the action of Salox, and the mode of stereocontrol.
A New Strategy to Fight Metallodrug Resistance: Mitochondria‐Relevant Treatment through Mitophagy to Inhibit Metabolic Adaptations of Cancer Cells
Authors: Wang Meng‐Meng , Xu Fu‐Jie , Su Yan , Geng Yun , Qian Xiao‐Ting , Xue Xu‐Ling , Kong Ya‐Qiong , Yu Zheng‐Hong , Liu Hong‐Ke , Su Zhi 
Published: April 2022

AbstractMetabolic adaptations can help cancer cells to escape from chemotherapeutics, mainly involving autophagy and ATP production. Herein, we report a new rhein‐based cyclometalated IrIII complex, Ir‐Rhein, that can accurately target mitochondria and effectively inhibit metabolic adaptations. The complex Ir‐Rhein induces severe mitochondrial damage and initiates mitophagy to reduce the number of mitochondria and subsequently inhibit both mitochondrial and glycolytic bioenergetics, which eventually leads to ATP starvation death. Moreover, Ir‐Rhein can overcome cisplatin resistance. Co‐incubation experiment, 3D tumor spheroids experiment and transcriptome analysis reveal that Ir‐Rhein shows promising antiproliferation performance for cisplatin‐resistant cancer cells with the regulation of platinum resistance‐related transporters. To our knowledge, this is a new strategy to overcome metallodrug resistance with a mitochondria‐relevant treatment.
An atlas of genetic correlations between gestational age and common psychiatric disorders
Authors: Yao Yao , Li Chun'e , Meng Peilin , Cheng Bolun , Cheng Shiqiang , Liu Li , Yang Xuena , Jia Yumeng , Wen Yan , Zhang Feng 
Published: April 2022

AbstractWe aim to systematically explore the potential genetic correlations between five major psychiatric disorders and gestational ages. Genome‐wide association study (GWAS) summary datasets of attention deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), bipolar disorder (BD), schizophrenia (SCZ) and major depressive disorder (MDD) in discovery were downloaded from the Psychiatric GWAS Consortium (PGC) website. Suggestive (Raw p < 0.05) genetic associations in the discovery phrase were further replicated in independent GWASs which downloaded from PGC, the FinnGen study or Integrative Psychiatric Research (iPSYCH) website. GWASs of gestational duration, preterm and post‐term birth were derived from previous studies of infants from the Early Growth Genetics (EGG) Consortium, the iPSYCH study, and the Genomic and Proteomic Network for Preterm Birth Research (GPN). We calculated genetic correlations using linkage disequilibrium score (LDSC) regression. Mendelian randomization (MR) analyses were performed to investigate the causal effects. We identified four suggestive genetic correlations between psychiatric disorders and gestational age factors in discovery LDSC and two replicated in a confirmation LDSC: gestational duration and ADHD (rg = −0.1405, FDR p = 0.0406), post‐term birth and SCZ (rg = −0.2003, FDR p = 0.0042). We also observed causal effect of post‐term birth on SCZ by MR (PWeighted median = 0.037, PInverse variance weighted = 0.007). Our analysis suggested no significant evidence of horizontal pleiotropy and heterogeneity. This study showed the genetic correlation evidences between gestational age phenotypes and psychiatric disorders, providing novel clues for understanding the pathogenic factors of common psychiatric disorders.Lay SummaryWhereas gestational age factors were reported to be associated with psychiatric disorders, the genetic relationship and causality remain to be revealed. The present study reported the first large‐scale genetic correlations investigation of the associations between gestational age phenotypes and psychiatric disorders. Results indicate causal relationships between post‐term birth and schizophrenia (SCZ), as well as suggestive genetic correlations between gestational duration and attention deficit/hyperactivity disorder (ADHD). This study provided novel clues for understanding the pathogenic factors of common psychiatric disorders.
Isopropenyl Esters (iPEs) in Green Organic Synthesis
Authors: Rigo Davide , Masters Anthony F. , Maschmeyer Thomas , Selva Maurizio , Fiorani Giulia 
Published: April 2022

AbstractThe need for greener compounds able to replace conventional ones with similar reactivity is crucial for the development of sustainable chemistry. Isopropenyl esters (iPEs) represent one eco‐friendly alternative to acyl halides and anhydrides. This review provides a comprehensive overview of the preparation methodologies and reported synthetic applications of iPEs and, in particular, of isopropenyl acetate (iPAc). Intriguingly, the presence of a C=C double bond adjacent to the ester functionality makes iPEs appealing in different chemoselective organic synthesis transformations. For instance, the acyl moiety is suitable for transesterification reactions in presence of different heteroatom‐based nucleophiles (C−, O−, N−, S−, Se−); these reactions are irreversible thanks to the formation of acetone, obtained upon keto‐enol tautomerization of the prop‐1‐en‐2‐ol (isopropenyl) leaving group. Similarly, the unsaturation contained in the isopropenyl synthon could be selectively exploited in organic synthesis for electrophilic and/or radical additions as well as in metal‐catalyzed cross‐coupling reactions. To conclude, iPEs recently found major interest in the direct modification of biomass (i.e. lignin or cellulose) and in the implementation of tandem reactions of esterification‐acetalization by exploiting the co‐formation of acetone during the reaction.
Comparing risk adjustment estimation methods under data availability constraints
Authors: Iommi Marica , Bergquist Savannah , Fiorentini Gianluca , Paolucci Francesco 
Published: April 2022

AbstractThe Italian National Healthcare Service relies on per capita allocation for healthcare funds, despite having a highly detailed and wide range of data to potentially build a complex risk‐adjustment formula. However, heterogeneity in data availability limits the development of a national model. This paper implements and ealuates machine learning (ML) and standard risk‐adjustment models on different data scenarios that a Region or Country may face, to optimize information with the most predictive model. We show that ML achieves a small but generally statistically insignificant improvement of adjusted R2 and mean squared error with fine data granularity compared to linear regression, while in coarse granularity and poor range of variables scenario no differences were observed. The advantage of ML algorithms is greater in the coarse granularity and fair/rich range of variables set and limited with fine granularity scenarios. The inclusion of detailed morbidity‐ and pharmacy‐based adjustors generally increases fit, although the trade‐off of creating adverse economic incentives must be considered.