bluuebunny/crossref_metadata_2025_split huggingface dataset:
A rehabilitation comparison of thoracoscopic and robotic lobectomy
Authors: Mo Xia , Shen Lei , Wang Min , Yang Jiahao 
Published: September 2022

Objective:
This study aimed to compare rehabilitation after lobectomy performed with a Da Vinci robot versus thoracoscopy.

Materials and Methods:
Patients who underwent lobectomy at the Changzhou First People’s Hospital from November 2020 to May 2021 were analyzed retrospectively, including 182 patients in the Da Vinci robot group and 280 patients in the thoracoscopy group. Postoperative hospital stay and postoperative pain were compared between groups.

Results:
The hospitalization cost of the Da Vinci robot group was $ 10874.06 ± 1757.07, which was higher than that of the thoracoscopy group ($ 7500.96 ± 1704.83). The postoperative hospital stay was significantly shorter in the Da Vinci robot group (4.74 ± 2.104 days) than that in the thoracoscopy group (5.55 ± 2.669 days; t = −3.664, P < 0.001). No significant differences between groups were observed in postoperative intensive care unit admission time and postoperative chest tube indwelling time. The proportion of patients with no pain 2 h after the operation was significantly higher in the Da Vinci robot group than in the thoracoscopy group (26.9% vs. 11.8%; χ
2 = 17.639, P < 0.001). The proportion of patients with no pain during the first activity was significantly higher in the Da Vinci robot group than in the thoracoscopy group (54.9% vs. 39.6%; χ
2 = 12.109, P = 0.004).

Conclusion:
The total cost of Da Vinci robotic surgery was higher than that of thoracoscopy for lobectomy, but the postoperative recovery was better, and the pain was less severe.
Serum levels of interleukin-6 and Vitamin D at the onset of multiple sclerosis and neuromyelitis optica
Authors: Ashtari Fereshteh , Madanian Reyhanehsadat , Zarkesh Sayyed Hamid , Ghalamkari Arshia 
Published: September 2022

Background:
Interleukin-6 (IL-6) is an important mediator in the acute phase of inflammatory diseases such as neuromyelitis optica (NMO) and multiple sclerosis (MS). The level of IL-6 is higher in cerebrospinal fluid and serum of NMO patients compare to MS. Vitamin D has a regulatory effect on IL-6, so it may have a negative correlation with IL-6 in the acute phase of these diseases. This study was performed to evaluate the serum levels of IL-6 and Vitamin D in NMO and MS patients at the onset of disease to find differences that may help in early diagnosis.

Materials and Methods:
This case–control study was done on patients with the first episode of optic neuritis, transverse myelitis, and area postrema syndrome who were referred to Kashani MS Center in Isfahan, Iran, between January 2018 and January 2020. The serum levels of Vitamin D and IL-6 were assessed using enzyme-linked immunosorbent assay in blood sample taken at the time of first presentation in patients who had a definitive diagnosis of NMO and MS during subsequent workup.

Results:
During a 2-year follow-up, definitive diagnosis of NMO was given in 25 cases, and they were compared with 25 cases that were randomly selected from patients with definite MS. Nineteen patients in the NMO group and 21 patients in the MS group were female. The mean age of patients in the NMO and MS groups was 29.64 ± 1.47 and 30.20 ± 1.42, respectively (P = 0.46). The mean of serum level of Vitamin D was 24.88 ± 15.2 in NMO patients and 21.56 ± 18.7 in MS patients without significant difference (P = 0.48). The mean of IL-6 was 30.1 ± 22.62 in the NMO group and 23.35 ± 18.8 in the MS group without significant difference (P = 0.28). The serum levels of Vitamin D were insufficient in both groups. No correlation between Vitamin D and IL-6 levels was found in our study (P > 0.05).

Conclusion:
Our results showed that serum IL-6 levels were higher at the onset of NMO disease compared with MS. The serum levels of Vitamin D were low in both groups and there was no association between serum levels of Vitamin D and IL-6 in either group. Future studies with large sample size are needed to confirm these findings.
Constructing a novel competing Endogenous RNAs network based on NR3C1 and X-linked inhibitor of apoptosis protein genes reveals potential prognostic biomarkers in colorectal cancer
Authors: Abdolvand Mohammad , Sadeghi Minoosh , Emami Mohammad Hassan , Fahim Alireza , Rahimi Hojjatolah , Amjadi Elham , Baghaei Abdolmehdi , Abdolvand Shirin , Maghool Fatemeh , Feizbakhshan Sara , Salmanizadeh Sharareh , Heidari Ehsan , Chehelgerdi Mohammad , Khodadoostan Mahsa , Ebrahim Maryam , Beni Faeze Ahmadi , Kazemi Mohammad , Hemati Simin , Khosravian Farinaz , Rahimi Hassan , Samadian Alireza , Salehi Mansoor 
Published: September 2022

Background:
Long noncoding RNAs (lncRNAs) have been recognized as the main modulatory molecules in various cancers and perform as competing endogenous RNAs (ceRNAs). The nuclear hormone receptor superfamily of ligand-activated transcription factors (NR3C1) regulates numerous proliferative and metabolic processes such as tumorigenesis and metabolic diseases. Furthermore, X-linked inhibitor of apoptosis protein (XIAP) belongs to a family of the inhibitors of apoptosis proteins, is located downstream of the glucocorticoid receptor (GR or NR3C1) pathway, and cooperates with GR to suppress apoptosis. However, the underlying mechanisms of NR3C1 and XIAP in colorectal cancer (CRC) remain mainly unclear. This research aims to clarify the potential RNA biomarkers and to construct a novel ceRNA network in CRC.

Materials and Methods:
Multistep bioinformatics methods such as Lnc2cancer and miRDB databases were applied to identify candidate lncRNAs and miRNAs. The interaction energy between lncRNAs, NR3C1, and XIAP genes was analyzed by the LncRRIsearch database. Plus, microRNAs and lncRNA were evaluated via the Diana tools database to select microRNAs with the most binding scores. Quantitative reverse transcription–polymerase chain reaction (QRT-PCR) was applied to verify RNA molecules’ expression levels and their association with the clinicopathological factors in 30 CRC tissues compared to 30 adjacent tissues.

Results:
QRT-PCR showed upregulation of KCNQ1OT1, NR3C1, and XIAP and downregulation of miR-421. The ceRNA network was constructed with 17 lncRNAs, 2 mRNAs, and 42 miRNAs. Thus, we explained the potential interactions between KCNQ1OT1 and miR-421 with NR3C1 and XIAP genes.

Conclusion:
Our study represents potential prognostic biomarkers and a new ceRNA network for further study in CRC.
Scientific Approaches to the Definition of Ethnо-Tourism Concept
Authors: Mukatova Rabiga , Mussina Kamshat , Rodríguez Maribel 
Published: September 2022

The relevance of this study is due to the fact that at present ethno-tourism is one of the most promising and popular areas in the world tourism market. The main purpose of study is to review and compare tourism development theories in terms of the main drivers of ethnо-tourism development. This article examines the theory of the ethnо-tourism concept development, their definitions and distinctive elements, the relationship between this type of tourism and ethnicity and cultural heritage. The authors compared the concept of ethnо-tourism with cultural and ethnоgraphic tourism, then revealed a strong tie between these concepts. In addition, the study examined the primary and secondary importance of cultural tourism and ethnо-tourism for tourists.
A systematic literature review was conducted in June 2022 based on two databases - ISI Web of Science and Scopus, the selected results were analyzed according to common characteristics and attributes: geographical location; assessment methods used in the article. According to the analyzed scientific papers, it was revealed that ethno-tourism research is gaining popularity in Asian countries, and comprehensive research methods are widely used.
In addition, this study emphasized the need for collaboration of tourists and local residents in organizing ethnо-tourism activities and the benefits from developing ethnо-tourism in the region for representatives of the local community and the regional economy were discussed. The role of ethnо-tourism in the preservation and protection of the cultural heritage of local communities were emphasized. Furthermore, the functions and main resources for the development of ethnо-tourism were analyzed.
#ELEITAS: violência simbólica e resistência em interações na página Quebrando o Tabu no Facebook sobre a participação feminina na política
Authors: Urrutia Dias Silveira Graciele 
Published: September 2022

Este artigo tem como objetivo principal compreender como a violência simbólica de gênero se manifesta nas trocas interacionais sobre a participação feminina em cenários de poder, como o da política, e identificar formas de resistência criadas pelas mulheres frente a possíveis manifestações de violência de gênero nos comentários das publicações analisadas. Para esse fim, a postagem foi analisada com base na pesquisa da Análise do Discurso Crítica (FAIRCLOUGH, 1989; 1992) e com o auxílio da Análise de Discurso Mediada por Computador, de Herring (2001; 2004). Entre os resultados, foi possível identificar que a violência simbólica nesse contexto pode ocorrer por meio de humor sexista, estereótipos, assim como de depreciação, o que permite analisar a reação das mulheres participantes, que usaram discursos contra-hegemônicos como estratégia de resistência à exposição de injustiças.
Health and Well-Being Interventions for Caregivers of Adults With Traumatic Brain Injury (2013–2020)
Authors: Acord-Vira Amanda , Davis Diana , Boyd Emily , Wheeler Steven 
Published: September 2022

Abstract
Systematic Review Briefs provide a summary of the findings from systematic reviews developed in conjunction with the American Occupational Therapy Association’s Evidence-Based Practice Program. Each Systematic Review Brief summarizes the evidence on a theme related to a systematic review topic. This Systematic Review Brief presents findings from the systematic review on interventions for caregivers of persons with traumatic brain injury that facilitate participation in the caregiver role.
Relationship Building Interventions for Caregivers of Adults With Traumatic Brain Injury (2013–2020)
Authors: Acord-Vira Amanda , Davis Diana , Boyd Emily , Wheeler Steven 
Published: September 2022

Abstract
Systematic Review Briefs provide a summary of the findings from systematic reviews developed in conjunction with the American Occupational Therapy Association’s Evidence-Based Practice Program. Each Systematic Review Brief summarizes the evidence on a theme related to a systematic review topic. This Systematic Review Brief presents findings from the systematic review on interventions for caregivers of persons with traumatic brain injury (TBI) that facilitate participation in the caregiver role.
Goal- and Client-Directed Interventions for Adults With Traumatic Brain Injury (2013–2020)
Authors: Wheeler Steven , Davis Diana , Basch Jamie , James Gracie , Lehman Brionna , Acord-Vira Amanda 
Published: September 2022

Abstract
Systematic Review Briefs provide a summary of the findings from systematic reviews developed in conjunction with the American Occupational Therapy Association’s Evidence-Based Practice Program. Each Systematic Review Brief summarizes the evidence on a theme related to a systematic review topic. This Systematic Review Brief presents findings from the systematic review on goal- and client-directed interventions to improve psychosocial outcomes for people with traumatic brain injury.
Harmonious Co-Existence between Nature and Mankind: An Investigation of a Satoyama Development – Like Mechanism at Imbak Canyon Conservation Area (ICCA), Sabah
Authors: Angki Tracy , Peters Robert Francis , Mohd Nordin Nordiana , Saikim Fiffy Hanisdah 
Published: September 2022

This research is a preliminary survey of Satoyama development-like mechanism in Kg. Imbak, Tongod, Sabah. The objectives of this research are to determine the utilization of forest source among the local community in Kg. Imbak and their community-based conservation efforts. Face to face interviews were conducted to access primary data besides observation surveys. The data gathered are from published materials such as reports and articles. Kg. Imbak consists of Dusun Sungai People with a total population of 796 people. Collected data were analyzed using Descriptive Analysis and SWOT analysis. Kg Imbak is approximately 19.12 km drive from Tongod District and the local community still consumes forest source for their medicinal needs, bush meat, handicraft and construction materials such as using Ironwood tree to make coffins. Based on data collected, the Internal Factor Estimate Matrix (IFEM) is 2.59 while the External Factor Estimate Matrix (EFEM) shows a total of 2.58 indicating that Kg. Imbak, Tongod has a great potential and opportunities in terms of practicing the Satoyama model. There are 52 strategies determined in this research by using pair wise matching SO, WO, ST and WT.
Butterfly (Lepidoptera: Papilionoidea) fauna of Kangkawat Research Station, Imbak Canyon Conservation Area, Sabah, Malaysia
Authors: Ismail Norradihah , Awg Abdul Rahman Aqilah , Mohamed Maryati , Japir Razy , Le Gao , Saikim Fiffy Hanisdah 
Published: September 2022

Forty-three species of butterflies from 36 genera and six families are reported for Kangkawat Research Station, Imbak Canyon Conservation Area (ICCA). This accounts for 4.6 percent of the 944 species reported in Borneo. Compared to studies from other localities in ICCA, the butterfly fauna in Kangkawat Research Station is diverse and evenly distributed with a Shannon’s index of Diversity (H’) value of 3.636 and Simpson’s index of Species Evenness (E1/D) value of 0.776.The most dominant family is Nymphalidae with 27 species recorded followed by Lycaenidae with 11 species. Seven species are new records for ICCA: Eurema blanda, Mycalesis dohertyi, Nacaduba berenice, Arhopala aedias agnis, Arhopala agesias, Drupadia cineas and Taractrocera ardonia. Three species: Mycalesis kina, Acytolepis ripte and Drupadia cineas, which are endemic to Borneo are also recorded here. The presence of the butterfly species of high conservation value highlights Kangkawat Research Station as an important area for conservation of these species.
Rapid Assessment of Nocturnal Sciurid and Avifauna Diversity in Kadamaian – Kinabalu Park for Ecotourism Potential
Authors: MN Arifuddin , M Izereen , T Fred , A Suganthi , VK Jayaraj 
Published: September 2022

A rapid assessment of sciurids and avifauna was done from 14th October 2020 – 20th October 2020 in Kadamaian – Kinabalu Park, Kota Belud, Sabah. Two sets of binoculars (Swarovski 8x30 and Bushnell 10x42) and two sets of Digital SLR cameras affixed with telephoto lens (Canon 7D; Tamron 150-600mm G2 F/4-6.3 and Nikon D500; Nikkor 200-500mm F/5.6) were used to aid in data collections. This assessment managed to record 5 species of Sciurids and 58 species of Avifauna in and around the Kadamaian-Kinabalu Park. Continuous biodiversity surveys are crucial in Kadamaian – Kinabalu, Sabah to maximize the potential ecotourism opportunity.
KONSEP JIHAD ULAMA MELAYU-ISLAM DALAM KITAB JAWI TERPILIH: SATU ANALISIS
Authors: RAHIMIN AFFANDI ABD RAHIM  , SYAMSUL AZIZUL MARINSAH  , AHMAD FARID ABD JALAL  
Published: September 2022

Sejarah Malaysia membuktikan perjuangan orang Melayu menentang penjajah di Tanah Melayu dilakukan oleh pelbagai pihak dan gerakan. Namun begitu, perjuangan golongan ulama dalam membebaskan Tanah Melayu daripada belenggu penjajahan kurang didedahkan. Justeru, objektif kajian ini cuba menganalisis konsep jihad ulama Melayu-Islam yang terkandung dalam kitab Jawi terpilih. Hal ini perlu bagi membuktikan peranan ulama Melayu Islam dalam menyemarakkan semangat nasionalisme seperti yang terkandung dalam fakta sejarah karya-karya kitab Jawi tersebut. Sehubungan dengan itu, kajian ini merupakan kajian kualitatif yang menggunakan metode pengumpulan data melalui kaedah kepustakaan dan analisis dokumen. Hasil kajian mendapati, peranan ulama Melayu-Islam dalam kebangkitan menentang penjajah terbukti, khususnya Ashab Jawi. Fakta sejarah dalam kitab Jawi yang dipilih membuktikan hal ini walaupun peranan mereka sering ditenggelamkan oleh paparan sejarah tajaan British. Mereka menonjolkan tokoh feudal Melayu sebagai pejuang kemerdekaan terawal. Pandangan palsu ini wajib diperbetulkan demi menimbulkan kebenaran dan menunjukkan dimensi jihad ulama Melayu bercirikan semangat keagamaan dan nasionalisme.

The history of Malaysia proves that various parties and movements carried out the struggle of the Malays against the colonialists in Malaya. However, the struggle of the ulama in liberating Malaya from the shackles of colonialism is less exposed. Thus, the objective of this study is an attempt to analyze the concept of jihad of Malay-Muslim scholars contained in selected Jawi books. This is necessary to prove the role of Malay Islamic scholars in igniting the spirit of nationalism as contained in the historical facts of the works of the Jawi book. Therefore, this is a qualitative study that employs data collection techniques such as library research and document analysis. The study results found that the Malay-Muslim scholarsplayed a signficant role in the uprising against the colonialists, specifically the Ashab Jawi. Historical facts in selected Jawi scriptures prove this even though their role is often over shadowed by British -sponsored historical displays. They highlighted Malay feudal figures as the earliest independence fighters. This false view must be addressed to reveal the truth and show the dimension of jihad of Malay scholars characterized by religious spirit and nationalism.
Immobilisation of Solvatochromic Dyes on Transparent Cellulose Films; an Improved Methodology for the Study of Homeopathic Potencies.
Authors: Cartwright Steven john 
Published: September 2022

Abstract
Background Highly diluted and succussed solutions (homeopathic potencies) have been shown to interact with a wide range of solvatochromic dyes based on changes in their UV-visible spectra. Studies so far have involved free dyes in solution, but there is a pressing need to find ways to investigate the potency-dye interaction using isolated dye molecules in order to ask more searching physico-chemical questions regarding the fundamental nature of potencies.
Aims and Methods The aims of the present study have been to look for ways to covalently immobilise solvatochromic dyes onto transparent cellulose films and hence be in a position to investigate dye-potency interactions without the complication of dye-dye interactions, including dye aggregation, which can occur with free dyes in solution.
Results To date a total of nine different dyes have been immobilised on cellulose films using epoxide activation of hydroxyl groups on the cellulose surface. Using this methodology studies have begun looking at the time course of potency action on one of these immobilised dyes, Brooker’s merocyanine. Results show that the interaction of Arsenicum 10M with this dye consists of three phases – an initial growth phase, a sustained plateau of interaction and a final decline phase lasting several days.
Conclusions A methodology has been developed that successfully immobilises solvatochromic dyes onto transparent cellulose film. These films can then be used in a spectrophotometer to study at a much more detailed level how potencies interact with dyes compared with using free dyes in solution. Results indicate that the information gained in this way provides new insights regarding the fundamental nature of potencies. Specifically, studies using immobilised Brooker’s merocyanine with Arsenicum 10M reveal that the lifetime of the potency is much longer than expected and that its action consists of three distinct phases, suggesting a resonant interaction with the dye.
High Dilutions of Drugs show Distinct Variation from each other in their Electronic Spectra
Authors: Sukul Nirmal Chandra , Ghosh Sumit , Singh Raj Kumar , Pande Nivedita , Sukul Anirban 
Published: September 2022

Drugs at high dilution (HD) produce therapeutic effect on man, animals and plants. Experimental evidence shows that free water molecules and hydrogen bond strength of OH groups constitute the physical basis of HDs which are otherwise devoid of original drugs molecules. HDs are produced in aqueous EtOH by serial dilution of a substance with mechanical agitation or succussion in each step, and are called potencies. Three potencies 6 cH, 12 cH and 30 cH of two drugs Anacardium orientale and Natrum muriaticum (NaCl) and their mother tincture (MT) are used in this study. Electronic spectra of these MTs and potencies, all in 90% EtOH, were taken in the wavelength region of 190 nm – 350 nm. The objective is to find out any additional physico-chemical entities in potencies besides the aforesaid two factors. It was reported earlier that charge transfer (CT) interaction accompanies potentization of drugs. This study focused on the CT interaction. The results indicate that spectral pattern and absorbance intensities of the test samples vary from each other. Potentization involves CT interaction in consecutive potencies. Water and EtOH do not form a homogeneous mixture and have aggregates of EtOH and water molecules. CT interactions occur in these individual aggregates and are mostly inter molecular within EtOH or water. These aggregates vary from each other in the test samples. It is concluded that water and EtOH aggregates and their relative distribution constitute additional phyco-chemical basis of potencies.
Update from the Clificol Project: Omicron in Hong-Kong and worldwide overview of the pandemic
Authors: Tournier Alexander , Fok Yvonne , Van Haselen Robbert 
Published: September 2022

Background: The Clificol® COVID-19 Support Project is an innovative international data collection project aimed at documenting the presenting symptoms, use of homeopathy through the pandemic and tackling some of the core questions in homeopathy.
Aims: The Covid-19 pandemic raised many questions and mobilised many resources. In order to make good use of resources, sound knowledge of the presenting complaints and demographics are required. In particular, we aimed to characterise the recent Omicron wave in Hong-Kong and to get an overall picture of the global pandemic as experienced by the homeopathic community.
Methodology: This online multi-national data-collection project is supported by the ECH, ECCH, ICH, HRI, LMHI, and other professional associations. The collected data includes demographic information, severity, conventional diagnosis and treatment, presenting symptoms as well as the remedies prescribed. The outcome of treatment was tracked using the ORIDL scale. More recently a 23-items prospective questionnaire was added to the input in order to gather targeted data about the presenting complaints.
Results and discussion: The recent wave of the Omicron variant in Hong-Kong, was analysed (N=372 cases) in terms of the symptomatology of this variant. The data from the 23-items questionnaire is compared to the longer questionnaire (150 items) used by the Hong-Kong team (21 practitioners). The most frequently reported common Clinical symptoms were extreme tiredness (60%), sore throat (46%), headache during fever (45%), dryness of mouth (37%), poor appetite (37%), runny nose (34%) and unusual muscle pains (31%).
Also, the cases collected from around the world over the course of the pandemic (N=1300) were analysed, providing an overall picture of the pandemic and its specificities per country and over time.
Conclusions: Clificol has shown and continues to show the value of data collection for the homeopathy community, providing important information for the management of future pandemics and opening new avenues for research in homeopathy.