bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrable and superintegrable extensions of the rational Calogero–Moser model in three dimensions
Authors: Fordy Allan P , Huang Qing 
Published: April 2022

Abstract
We consider a class of Hamiltonian systems in 3 degrees of freedom, with a particular type of quadratic integral and which includes the rational Calogero–Moser system as a particular case. For the general class, we introduce separation coordinates to find the general separable (and therefore Liouville integrable) system, with two quadratic integrals. This gives a coupling of the Calogero–Moser system with a large class of potentials, generalising the series of potentials which are separable in parabolic coordinates. Particular cases are superintegrable, including Kepler and a resonant oscillator. The initial calculations of the paper are concerned with the flat (Cartesian type) kinetic energy, but in section 5, we introduce a conformal factor
φ to H and extend the two quadratic integrals to this case. All the previous results are generalised to this case. We then introduce some two and three dimensional symmetry algebras of the Kinetic energy (Killing vectors), which restrict the conformal factor. This enables us to reduce our systems from 3 to 2 degrees of freedom, giving rise to many interesting systems, including both Kepler type and Hénon–Heiles type potentials on a Darboux–Koenigs D
2 background.
A generalization of Laurent biorthogonal polynomials and related integrable lattices
Authors: Wang Bao , Chang Xiang-Ke , Yue Xiao-Lu 
Published: April 2022

Abstract
This paper is concerned about certain generalization of Laurent biorthogonal polynomials together with the corresponding related integrable lattices. On one hand, a generalization for Laurent biorthogonal polynomials is proposed and its recurrence relation and Christoffel transformation are derived. On the other hand, it turns out the compatibility condition between the recurrence relation and the Christoffel transformation for the generalized Laurent biorthogonal polynomials yields an extension of the fully discrete relativistic Toda lattice. And also, it is shown that isospectral deformations of the generalized Laurent biorthogonal polynomials lead to two different generalizations of the continuous-time relativistic Toda lattice, one of which can reduce to the Narita–Itoh–Bogoyavlensky lattice.
Effect of rotating liquid samples on dynamic propagation and aqueous activation of a helium plasma jet
Authors: XU Han , GUO Shaoshuai , ZHANG Hao , XIE Kai 
Published: March 2022

Abstract
This paper aims to explore the effects of a rotating plasma-activated liquid on the dynamic propagation and biomedical application of a helium plasma jet. The spatial distribution of reactive species and the associated physico-chemical reactions are altered by the rotating liquid, which shows a significant weakening in the axial propagation of the plasma bullet and a strengthening in its radial expansion at the liquid surface. The phenomenon is prompted by the nonzero rotational velocity of the liquid and is regulated by airflow, target distance and liquid permittivity. The concentrations of aqueous reactive species, especially OH and

O

2

−

,

and the inactivation effectiveness on cancer cells are weakened, indicating that a rotating liquid is not conducive to water treatment of the plasma jet although the treatment area of the plasma jet increases dynamically. This finding is of significance for the plasma–liquid interaction and the biomedical-related applications of plasma jets.
Too close for comfort? COVID-19-related stress among older couples and the moderating role of closeness
Authors: Birditt Kira , Turkelson Angela , Oya Angela 
Published: March 2022

Abstract
Married and cohabiting couples have important influences on one another’s stress and well-being. Pandemic-related stress may influence the extent to which couples' stress levels are coregulated. This study examined the experience of nonspecific stress and pandemic-related stress and the moderating role of closeness among couples aged 50 and over in which at least one member had hypertension. A total of 30 couples reported their feelings of closeness to one another in a baseline interview and their feelings of nonspecific stress and pandemic-related stress every three hours for 5 days. There was no difference in closeness and nonspecific stress between husbands and wives. Wives reported greater pandemic-related stress than husbands. Actor-partner interdependence models revealed that wives’ nonspecific stress predicted husbands’ nonspecific stress (b = 0.17, SE = 0.04, p &lt; .001) and that husbands’ nonspecific stress predicted wives’ nonspecific stress in each three hour period (b = 0.19, SE = 0.04, p &lt; .001) and these associations were not moderated by closeness. Coregulation in pandemic-related stress among husbands and wives was moderated by wives’ feelings of closeness such that when wives’ feelings of closeness were lower, greater husband pandemic-related stress predicted lower pandemic-related stress for wives (b = -0.16, SE = 0.07, p &lt; .05) whereas when wives’ feelings of closeness were higher, greater husband pandemic-related stress predicted greater pandemic-related stress for wives (b = 0.22, SE = 0.09, p &lt; .05). These findings indicate that closeness may have detrimental effects especially when considering emotional coregulation in couples regarding the pandemic.
Your suffering is also mine: Older and younger couples’ responses to the partner’s upsetting memory
Authors: Cortez Jared Isaac , Wilson Stephanie J , Shrout M Rosie , Kiecolt-Glaser Janice 
Published: March 2022

Abstract
Aging theories posit that older adults maximize their well-being by regulating their emotions and investing in their closest relationships. Most research has examined these mechanisms using study confederates rather than close dyads. The existing work on couples has focused on marital conflict; none has examined responses to the spouse’s emotional suffering. To address this, 107 married couples ages 40-86 listened to their partner disclose an upsetting personal memory. Afterward, listeners rated their own and their partner’s emotions and perspective-taking; observers reliably coded listeners’ engagement and disclosers’ emotional intensity. Aging theories offer competing predictions: older listeners may disengage from their partner’s disclosure to avoid experiencing negative emotions. Alternatively, older adults may be more engaged and thus more reactive, given the increased investment in their close relationships. Findings showed that older listeners rated their disclosing partner as less sad compared to younger counterparts (p &lt; .05). However, this effect was attenuated (p = .077) by observed emotional intensity, as older disclosers exhibited less intense emotions. There were no age differences in listeners’ own reactivity, perspective-taking, or observed engagement. Taken together, older adults disclosed with less emotional intensity, consistent with theory. By contrast, older listeners’ ratings were validated by external coders, not driven by positivity biases. Further, older listeners were no more or less engaged or reactive to their spouse’s disclosure than younger listeners. This study highlights a context wherein social and emotional motivations are at odds. Teasing these motivations apart will help us to better understand how social-emotional processes develop across adulthood.
Caspar, an adapter for VAPB and TER94, modulates the progression of ALS8 by regulating IMD/NFκB-mediated glial inflammation in aDrosophilamodel of human disease
Authors: Tendulkar Shweta , Hegde Sushmitha , Garg Lovleen , Thulasidharan Aparna , Kaduskar Bhagyashree , Ratnaparkhi Anuradha , Ratnaparkhi Girish S 
Published: April 2022

AbstractAmyotrophic lateral sclerosis (ALS) is a fatal, late-onset, progressive motor neurodegenerative disorder. A key pathological feature of the disease is the presence of heavily ubiquitinated protein inclusions. Both the unfolded protein response and the ubiquitin–proteasome system appear significantly impaired in patients and animal models of ALS. We have studied cellular and molecular mechanisms involved in ALS using a vesicle-associated membrane protein-associated protein B (VAPB/ALS8) Drosophila model [Moustaqim-Barrette, A., Lin, Y.Q., Pradhan, S., Neely, G.G., Bellen, H.J. and Tsuda, H. (2014) The ALS 8 protein, VAP, is required for ER protein quality control. Hum. Mol. Genet., 23, 1975–1989], which mimics many systemic aspects of the human disease. Here, we show that VAPB, located on the cytoplasmic face of the endoplasmic reticulum membrane, interacts with Caspar, an orthologue of human fas associated factor 1 (FAF1). Caspar, in turn, interacts with transitional endoplasmic reticulum ATPase (TER94), a fly orthologue of ALS14 (VCP/p97, valosin-containing protein). Caspar overexpression in the glia extends lifespan and also slows the progression of motor dysfunction in the ALS8 disease model, a phenomenon that we ascribe to its ability to restrain age-dependent inflammation, which is modulated by Relish/NFκB signalling. Caspar binds to VAPB via an FFAT motif, and we find that Caspar’s ability to negatively regulate NFκB signalling is not dependent on the VAPB:Caspar interaction. We hypothesize that Caspar is a key molecule in the pathogenesis of ALS. The VAPB:Caspar:TER94 complex appears to be a candidate for regulating both protein homeostasis and NFκB signalling, with our study highlighting a role for Caspar in glial inflammation. We project human FAF1 as an important protein target to alleviate the progression of motor neuron disease.
Janelle Monáe, Dirty Computers, and Embodied Posthumanism
Authors: Rodine Zoë 
Published: April 2022

Abstract
Janelle Monáe has been a driving force in Afrofuturism and a practical theorist of Black embodiment for the past fifteen years, and with her 2018 album and (e)motion picture, Dirty Computer, she has cemented herself as a pop sensation. While many critics have celebrated Dirty Computer for its embrace of queer identity and assertion of Black humanity, they have often done so by pitting it against her earlier work, which often features her cyborg alter-ego and riffs on iconic imagery from the films Metropolis (1927) and Blade Runner (1982), aligning her with speculative traditions concerned with the enmeshment of human and machine. I argue that the formulation of the “dirty computer” is not a departure but an intensification and distillation of her commitment to deconstructing the category of the human and disrupting the human/machine divide. The body as dirty computer interrogates the efficacy of Donna J. Haraway’s version of cyborg being for Black women, whose bodies have been scripted as less-than-human for so long, by calling on Black feminist traditions from Hortense J. Spillers onward that center fleshy materiality as a means of resistance to the hegemonic construction of the human body. In conversation with scholars such as Alexander Weheliye and Uri McMillan, who argue that Blackness is itself a technics, the dirty computer performs an always already virtual Black body materialized through technologies of the voice and citational practices that disrupt linear temporality. Monáe articulates an Afrofuturist feminist vision for embodiment that rejects transhumanism by embracing the messiness of the body as an essential tool for testifying.
Association Between the Intracellular Tacrolimus Concentration in CD3+ T Lymphocytes and CD14+ Monocytes and Acute Kidney Transplant Rejection
Authors: Udomkarnjananun Suwasin , Francke Marith I. , Dieterich Marjolein , van de Velde Daan , Verhoeven Jeroen G. H. P. , Boer Karin , Clahsen-Van Groningen Marian C. , De Winter Brenda C. M. , Baan Carla C. , Hesselink Dennis A. 
Published: March 2022

Background:
Intracellular tacrolimus concentration in peripheral blood mononuclear cells (PBMCs) (TAC[PBMC]) has been proposed to better represent its active concentration than its whole blood concentration. As tacrolimus acts on T lymphocytes and other white blood cells, including monocytes, we investigated the association of tacrolimus concentration in CD3+ T lymphocytes (TAC[CD3]) and CD14+ monocytes (TAC[CD14]) with acute rejection after kidney transplantation.

Methods:
From a total of 61 samples in this case–control study, 28 samples were obtained during biopsy-proven acute rejection (rejection group), and 33 samples were obtained in the absence of rejection (control group). PBMCs were collected from both cryopreserved (retrospectively) and freshly obtained (prospectively) samples. CD3+ T lymphocytes and CD14+ monocytes were isolated from PBMCs, and their intracellular tacrolimus concentrations were measured.

Results:
The correlation between tacrolimus whole-blood and intracellular concentrations was poor. TAC[CD3] was significantly lower than TAC[CD14] (median 12.8 versus 81.6 pg/million cells; P < 0.001). No difference in TAC[PBMC] (48.5 versus 44.4 pg/million cells; P = 0.82), TAC[CD3] (13.4 versus 12.5 pg/million cells; P = 0.28), and TAC[CD14] (90.0 versus 72.8 pg/million cells; P = 0.27) was found between the rejection and control groups. However, freshly isolated PBMCs showed significantly higher TAC[PBMC] than PBMCs from cryopreserved samples. Subgroup analysis of intracellular tacrolimus concentrations from freshly isolated cells did not show a difference between rejectors and nonrejectors.

Conclusions:
Differences in TAC[CD3] and TAC[CD14] between patients with and without rejection could not be demonstrated. However, further optimization of the cell isolation process is required because a difference in TAC[PBMC] between fresh and cryopreserved cells was observed. These results need to be confirmed in a study with a larger number of patients.
Characteristics and Outcomes of Black and White Patients Hospitalized With Nonalcoholic Steatohepatitis
Authors: Qayed Emad , Migdal Alexandra L. , Jagannathan Ram , Miller Lesley S. , Pasquel Francisco J. 
Published: March 2022

Background:
Nonalcoholic steatohepatitis (NASH) is an increasingly common etiology for liver-related hospitalizations in the United States. The aim of this study was to examine the differences of disease characteristics and outcomes between hospitalized Black and White patients with NASH.

Materials and Methods:
We used the National Inpatient Sample (NIS) to identify all adult hospitalizations with NASH (ICD-10 code: K75.81) from 2016 to 2018. We compared demographic and clinical characteristics between Black and White patients. Multivariable models were computed to compare all-cause mortality, length of stay (LOS), and total hospital costs between the groups.

Results:
There were 43,409 hospitalizations with NASH (41,143 White, 2266 Black). Black patients were less likely to have cirrhosis (33.6%) compared with Whites (56.4%), P<0.0001. Black patients were less likely to have esophageal variceal bleeding (1.2% vs. 3.5%), ascites (17.1% vs. 28.8%), and acute liver failure (16.2% vs. 28.9%) compared with Whites (all P<0.0001). These findings were consistent among patients with cirrhosis. Mortality was higher among Blacks compared with Whites (3.9% vs. 3.7%, adjusted odds ratio=1.34; 95% confidence interval: 1.05-1.71, P=0.018). Compared with Whites, Blacks had a longer LOS (6.3 vs. 5.6, P<0.001), and higher hospital costs ($18,602 vs. $17,467; P=0.03).

Conclusion:
In this large population of inpatients with NASH, Black patients were less likely to have cirrhosis and liver disease-related complications, but had overall worse hospital mortality, longer LOS, and higher hospital costs. Further research is warranted to elaborate on factors that generate the health inequities in NASH outcomes between Black and White patients.
Hypertension in Quilombola children and adolescents
Authors: de Jesus Viviane Silva , da Conceição Nascimento Costa Maria , de Camargo Climene Laura , Trad Leny Alves Bomfim , Nery Joilda Silva 
Published: March 2022

Abstract
To determine the prevalence of prehypertension (PH) and hypertension (AH) in quilombola children and adolescents, as well as to analyze sociodemographic, behavioral, and health characteristics.
Prevalence study conducted in random samples of quilombola children and adolescents from 06 to 19 years of age, in remaining quilombo communities in Cachoeira-Bahia. Identification, sociodemographic, behavioral, anthropometric, and blood pressure (BP) data were used. Descriptive analyses of the variables of interest were performed based on absolute (N) and included frequencies (percentage, prevalence). Pearson’s Chi-square (χ
2) and Fisher Exact tests determined possible differences.
Of the 668 participants, 54.3% were children, 51.2% were male, and 29.4% presented alterations in BP. PH and AH were found in 12.7% and 14.3% of the children, respectively; for adolescents, these values were 12.5% and 15.4%, respectively. No statistically significant difference was found between the prevalence of AH in the 2 population groups, nor between the PH measurements. Most families reported a low socioeconomic status. Among children, 6.6% were underweight, 14.6% were overweight, 10.7% were obese, 12.7% presented a Waist-to-Height Ratio (WHtR) > 0.5; 70.1% were inactive and 88.4% had a sedentary lifestyle; 5.6% of the adolescents were underweight, 12.8% were overweight, 9.2% were obese, 11.5% presented a WHtR > 0.5; 78% were inactive and 92.1% had a sedentary lifestyle. Normotensive children and adolescents, and those with alterations in BP differed only in terms of the Body Mass Index (P = .007) and WHtR (P < .001). The consumption of unhealthy foods was high.
The high prevalence of PH and AH, as well as of exposure to potential risk factors for AH in quilombola children and adolescents, reveals a worrisome situation, and demands further studies to identify risk factors for this disease and the need for interventions beyond the health sector, especially as regards disease prevention and control in the early stages of life, aiming to reduce its prevalence as adults.
Transverse thoracic muscle plane block as a routine strategy for cardiac enhanced recovery after surgery in sternotomy
Authors: Deng Qiweixi , Zheng Chuandong , Xia Keshu 
Published: March 2022

Abstract
The aim of this study is to retrospectively analyze and evaluate the effect of transverse thoracic muscle plane (TTP) block as a routine analgesic strategy for cardiac enhanced recovery after surgery in sternotomy.
Patients received TTP block after general anesthesia and tracheal intubation were included in this study. The baseline clinical data of the patients, intraoperative use of sufentanil, internal mammary artery separating time, the postoperative duration of invasive ventilation, visual analogue scale, the compression times of patient-controlled intravenous analgesia in the first 3 days after surgery, and postoperative nausea and vomiting were recorded.
A total of 104 cases was included and divided to G group (without TTP block) and TTP group (with TTP). Sufentanil use (sufentanil dose/min, sufentanil dose/kg body weight, sufentanil dose/[min kg]) in TTP group was significantly lower than that of G group. In G group, intraoperative use of sufentanil was correlated to the duration of anesthesia (P = .035). The postoperative visual analogue scale pain scores and the compression times of patient-controlled intravenous analgesia in the TTP group were significantly decreased compared with G group (P < .01). The postoperative duration of invasive ventilation of patients with normal and mildly impaired pulmonary function was significantly correlated to the use of sufentanil (P = .027, .009).
TTP block has certain analgesic effect and can reduce sufentanil use in medium-length cardiac surgery and postoperative use of opioids. It is indicated that TTP block can be used as a routine enhanced recovery after surgery strategy for sternotomy in cardiac surgery.
Esophageal stenosis after chemotherapy for breast cancer
Authors: Ou Zhen-Fei , Ren Lin-Lin , Yin Xiao-Yan , Zhang Cui-Ping , Xu Yong-Hong , Min Cong-Cong 
Published: March 2022

Abstract

Rationale:
Esophageal stenosis after chemotherapy in breast cancer patients is rare. Distinguishing esophageal stenosis from esophageal metastasis caused by breast cancer is important.

Patient concerns and diagnosis:
A 62-year-old woman diagnosed with advanced breast cancer and no distant metastases gradually developed skin changes, oral ulcers and mucosal injures after four cycles of chemotherapy. Dysphagia was the most severe symptom that greatly affected the patient’s quality of life. Ultimately, esophageal stenosis and ulceration were confirmed by serial radiological examinations and endoscopic biopsy.

Interventions:
Due to difficulties in eating orally, the patient was initially placed on a nasogastric tube in order to improve her nutritional status. Simultaneously, she was administered powerful proton pump inhibitors. She underwent modified radical mastectomy for breast cancer after her nutritional status improved. However, the patient was still suffering from severe dysphagia after more than 4 months of follow-up. Subsequently, she underwent removable esophageal stent implantation after after unsuccessful attempts to dilate her esophagus.

Outcomes:
The dysphagia symptoms were immediately alleviated to a certain degree, and the dilated cavity of the upper esophagus showed slight retraction.

Lessons:
Esophageal stenosis is very infrequent in patients with breast cancer after chemotherapy. It needs to be. distinguished from esophageal metastasis caused by breast cancer. Esophageal stent implantation may provide benefits in terms of both symptom control and survival in patients with severe esophageal structures.
Shaoyao Gancao Decoction for limb dysfunction after fractures around the knee
Authors: Shi Xiaohua , Bai Yu , He Xiaoming , Wang Aiguo 
Published: March 2022

Abstract

Background:
After reduction and fixation of a fracture around the knee (FAK), excessive injury, improper treatment, soft tissue damage, and blood circulation damage often lead to limb dysfunction, which seriously affects limb rehabilitation and the patient’s quality of life. Shaoyao Gancao Decoction (SGD) is an important means of treatment; however, it is not widely applied because of the lack of evidence about the effectiveness of oral drugs in the treatment of limb dysfunction. This study aimed to evaluate the effects of SGD on patients with limb dysfunction from the perspectives of pain, limb edema, stiffness, as well as physical dysfunction.

Methods:
The Chinese and English databases, the Wanfang database, Cochrane Library, China National Knowledge Infrastructure, EMBASE, China BioMedical Literature, PubMed, and Web of Science will be searched from inception to September 30, 2021. Both researchers will select the articles, collect the data and evaluate the quality of the methodology independently using the Cochrane bias risk tool.

Results:
High-quality evidence will be obtained to evaluate the beneficial and detrimental effects of SGD on limb dysfunction after FAK, including knee pain, limb edema, stiffness, and physical dysfunction, as well as adverse events.

Conclusion:
This study will provide evidence regarding whether SGD is beneficial for treating limb dysfunction after FAK in humans.

INPLASY registration number:
INPLASY202210028.