bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthetic Mucin Gels with Self‐Healing Properties Augment Lubricity and Inhibit HIV‐1 and HSV‐2 Transmission
Authors: Kretschmer Martin , Ceña‐Diez Rafael , Butnarasu Cosmin , Silveira Valentin , Dobryden Illia , Visentin Sonja , Berglund Per , Sönnerborg Anders , Lieleg Oliver , Crouzier Thomas , Yan Hongji 
Published: September 2022

AbstractMucus is a self‐healing gel that lubricates the moist epithelium and provides protection against viruses by binding to viruses smaller than the gel's mesh size and removing them from the mucosal surface by active mucus turnover. As the primary nonaqueous components of mucus (≈0.2%–5%, wt/v), mucins are critical to this function because the dense arrangement of mucin glycans allows multivalence of binding. Following nature's example, bovine submaxillary mucins (BSMs) are assembled into “mucus‐like” gels (5%, wt/v) by dynamic covalent crosslinking reactions. The gels exhibit transient liquefaction under high shear strain and immediate self‐healing behavior. This study shows that these material properties are essential to provide lubricity. The gels efficiently reduce human immunodeficiency virus type 1 (HIV‐1) and genital herpes virus type 2 (HSV‐2) infectivity for various types of cells. In contrast, simple mucin solutions, which lack the structural makeup, inhibit HIV‐1 significantly less and do not inhibit HSV‐2. Mechanistically, the prophylaxis of HIV‐1 infection by BSM gels is found to be that the gels trap HIV‐1 by binding to the envelope glycoprotein gp120 and suppress cytokine production during viral exposure. Therefore, the authors believe the gels are promising for further development as personal lubricants that can limit viral transmission.
Interactive effect of water and nitrogen fertilization improve chlorophyll fluorescence and yield of maize
Authors: Gao Fei , Wang Gui Yang , Muhammad Ihsan , Tung Shahbaz Atta , Zhou Xun Bo 
Published: September 2022

AbstractWater scarcity and excessive N fertilization have a negative effect on maize (Zea mays L.) production. Low water and N fertilization are the major problem in sustainable agriculture by limiting crop growth and development. However, the combined effect of N fertilization and supplementary irrigation on chlorophyll fluorescence and maize yield is still not understood. The objective of the study was to signify the effect of supplementary irrigation and N fertilization on leaf area index (LAI), relative chlorophyll content (SPAD), maximum photosynthetic capacity (Fv/Fm), photochemical quenching coefficient (qP), and yield. The experiment was conducted in a split‐plot design, with water management in main plot and N fertilization in subplot with three replications. Treatments included two water managements, that is, rainfed (natural rainfall) and irrigation water (70% field capacity). Five N fertilization rates were N0 (0 kg N ha−1), N150 (150 kg N ha−1), N200 (200 kg N ha−1), N250 (250 kg ha−1), and N300 (300 kg N ha−1). The LAI, SPAD, Fv/Fm, qP, and yield were significantly affected by water management, N rates, and their interaction (P < .05). The LAI, SPAD, Fv/Fm, qP, total dry matter accumulation, and yield under supplementary irrigation were significantly increased by 10.99, 5.75, 6.57, 9.14, 15.64, and 14.58% than those under rainfed conditions, but the nonphotochemical quenching coefficient was significantly decreased by 22.82%. The 250 kg N ha−1 increased grain yield under irrigated conditions than that of other N treatments. The interaction between water management and N fertilization significantly and positively affected the SPAD, Fv/Fm, and grain yield in both years, but had no significant effect on LAI during 2021 and HI during 2020 and 2021. We concluded that N250 treatment with supplementary irrigation increased grain yield.
Silicon Catalyzed C−O Bond Ring Closing Metathesis of Polyethers
Authors: Ansmann Nils , Thorwart Thaddäus , Greb Lutz 
Published: September 2022

AbstractThe Lewis superacid bis(perchlorocatecholato)silane catalyzes C−O bond metathesis of alkyl ethers with an efficiency outperforming all earlier reported systems. Chemoselective ring contractions of macrocyclic crown ethers enable substrate‐specific transformations, and an unprecedented ring‐closing metathesis of polyethylene glycols allows polymer‐selective degradation. Quantum chemical computations scrutinize a high Lewis acidity paired with a simultaneous low propensity for polydentate substrate binding as critical for successful catalysis. Based on these mechanistic insights, a second‐generation class of silicon Lewis superacid with enhanced efficacy is identified and demonstrated.
Synthesis and Structural Verification of an ArI(OTf)2, NO2‐Ph‐I(OTf)2**
Authors: Sharp‐Bucknall Lachlan , Tania  , Dutton Jason L. 
Published: September 2022

AbstractPhI(OTf)2 and related ArI(OTf)2 species have been incorrectly invoked as intermediates in oxidation reactions for many years. We recently established that such compounds did not yet exist but remain an attractive target. Here we describe the synthesis, isolation, and structural characterization of NO2‐PhI(OTf)2, which is resistant to decomposition and more reactive than PhI(OTf)(OAc), the species previously misidentified as PhI(OTf)2.
Ruthenium(II)/Imidazolidincarbonsäure‐katalysierte C−H‐Alkylierung für zentrale und axiale Doppelenantioinduktion
Authors: Li Yanjun , Liou Yan‐Cheng , Oliveira João C. A. , Ackermann Lutz 
Published: September 2022

AbstractDie enantioselektive C−H‐Aktivierung hat sich zu einem transformativen Werkzeug für den effizienten Aufbau chiraler Moleküle entwickelt. Trotz großer Fortschritte in der Rhodium‐ und Palladiumkatalyse hat sich die ruthenium(II)‐katalysierte enantioselektive C−H‐Aktivierung bisher jedoch als weitgehend herausfordernd erwiesen. Im Gegensatz dazu berichten wir nun über eine ruthenium(II)‐katalysierte hochregio‐, diastereo‐ und enantioselektive C−H‐Alkylierung. Als Schlüssel zum Erfolg wurden C2‐symmetrischen chiralen Imidazolidincarbonsäuren (CICAs), die leicht in einer Eintopfreaktion hergestellt werden können, als hochwirksame chirale Liganden identifiziert. Dieses Ruthenium/CICA‐System ermöglichte die effiziente Installation der zentralen und axialen Chiralität und verfügte über ausgezeichnete verzweigte bis lineare Verhältnisse mit im Allgemeinen >20 : 1 dr und bis zu 98 : 2 er. Experimentelle und computerchemische mechanistische Studien wurden durchgeführt, um die Wirkungsweise des Katalysators zu entschlüsseln.
Enantioselective Synthesis of N−N Bisindole Atropisomers
Authors: Zhang Peng , Xu Qi , Wang Xiao‐Mei , Feng Jia , Lu Chuan‐Jun , Li Yingzi , Liu Ren‐Rong 
Published: September 2022

AbstractN−N Atropisomers are a common motif in natural products and represent a significant dimension for exploration in modern pharmaceutical and medicinal chemistry. However, the catalytic atroposelective synthesis of such molecules remains challenging, hampering meaningful development. In particular, an enantioselective synthesis of N−N bisindole atropisomers is unprecedented. Herein, the first enantioselective synthesis of N−N bisindole atropisomers via the palladium‐catalyzed de novo construction of one indole skeleton is presented. A wide variety of N−N axially chiral bisindoles were generated in good yields with excellent enantioselectivities via a cascade condensation/N‐arylation reaction. Structurally diverse indole‐pyrrole, indole‐carbazole, and non‐biaryl‐indole atropisomers possessing a chiral N−N axis were accessed using this protocol. Moreover, investigations using density functional theory (DFT) calculations provided insight into the reaction mechanism and enantiocontrol.
Impact of dope extrusion rate and multilayer polydimethylsiloxane coating on asymmetric polyethersulfone hollow fiber membrane for CO2/N2 and CO2/CH4 separation
Authors: Zainuddin Muhd Izzudin Fikry , Ahmad Abdul Latif 
Published: September 2022

AbstractCarbon dioxide (CO2) emissions to the atmosphere have greatly contributed to climate change as the concentration has increased since the pre‐industrial period. Various mitigation strategies have been developed to combat climate change with membrane being one of the growing alternatives. Pristine hollow fiber (HF) membrane typically exhibits lower selectivity as compared to dense flat sheet membrane. In this study, we developed an asymmetric HF polyethersulfone (PES) membrane with critical concentration at two different dope extrusion rate (DER) at 3 and 6 mL/min to be studied for CO2/N2 and CO2/CH4 gas separation for flue gas and biogas upgrading applications by testing the fabricated membrane with pure gas permeation test with variable pressure at room temperature. It was observed that HF membrane extruded with high DER exhibits finger‐like structure beneath the skin layer with more pinholes compared to HF extruded with low DER. The gas permeance was observed to increase in linear fashion as function of upstream pressure while the gas selectivity appears to be relatively constant regardless of upstream pressure. Meanwhile, polydimethylsiloxane (PDMS) coated HF PES membrane shows lower gas permeance as compared to its pristine membrane with improved CO2/N2 and CO2/CH4 selectivity. HF PES membrane extruded at 3 mL/min shows relatively low gas permeance, CO2/N2 and CO2/CH4 selectivity as compared to HF PES extruded at 6 mL/min. Additionally, this study shows that sequential coating of PDMS layer does not improve gas selectivity performance of the fabricated asymmetric PES HF membrane while the gas permeance reduction was observed.
Complete mitochondrial genome of Distenia punctulatoides (Coleoptera: Chrysomeloidea: Disteniinae) and its phylogenetic implications
Authors: Nie Ruie E. , Gao Rong‐Rong , Yang Xing‐Ke , Lin Mei‐Ying 
Published: September 2022

AbstractThe family Disteniidae is a moderately large and widely distributed lineage. Distenia punctulatoides belongs to the family Disteniidae from the cerambycoid assemblage. Here, we report the complete mitogenome of D. punctulatoides, which is 15,675 bp in length. It contains 37 genes and a noncoding control region, which are arranged in the same order as that of the putative ancestor of beetles. The total base composition of the new mitogenome is 40.2% for A, 17.1% for C, 10.0% for G, and 32.7% for T. The new mitogenomic organization, nucleotide composition, and codon usage do not differ significantly from other beetles. Using available complete mitogenomes, the high‐level phylogeny of the family Disteniidae was explored. The phylogenetic analyses showed that Disteniidae were monophyletic, and the genus Distenia grouped with the genus Clytomelegena as sister groups. Combining the morphological and molecular data, Typodryas Thomson, 1864 is suggested to be a junior synonym of Distenia Lepeletier and Audinet‐Serville, 1828.
Comparison of geophysical prospecting and geochemical prospecting at the medieval and modern Cistercian Abbey of Carnoët (Finistère, France)
Authors: Laenger Arthur , Martel Arnaud , Boucher Fabien , François Xavier , Dabas Michel , Rouillard Joséphine , Durand Aline 
Published: September 2022

AbstractSaint‐Maurice Abbey in Carnoët (Finistère) underwent an in‐depth archaeological appraisal during 2018–2019, involving several non‐destructive technologies: the geophysical survey revealed the presence of expected structures, drawn on ancient plans, but also the presence of structures unknown up until now. A group of buildings on the edge of the pond in particular raised several questions. A geochemical survey was carried out there in order to try to characterize these buildings and observe the potential complementarity between geophysical and geochemical surveys. The results of the chemical analysis do not highlight the same level of detail of the structures as electrical resistivity, but these analyses seem to be able to clarify the geophysical diagnosis by discriminating signals of structures from echoes linked to the geological substrate.
Spatial correction of low‐cost sensors observations for fusion of air quality measurements
Authors: Bobbia Michel , Poggi Jean‐Michel , Portier Bruno 
Published: September 2022

AbstractThe context for this article is the statistical fusion of several pollutant measurement networks: a reference one of fixed sensors of high quality and others of fixed or mobile micro‐sensors of heterogeneous quality. The challenge is to use together the measurements of such different networks to obtain a better air quality map. Since pollution maps are often obtained from the correction of numerical model outputs by the measurements provided by the monitoring stations of air quality networks, the quality of the reconstructed map may be improved by increasing the density of sensors by adding low‐cost micro‐sensors. A geostatistical approach is very often used for the fusion of measurements. But the first step is to correct micro‐sensors measures using those given by the reference sensors. Usually, this preprocessing is performed during an offline preliminary study for which reference and micro‐sensor are located at the same position, which does not allow to adapt quickly to changes and to cope with time‐related nonstationarities. We propose in this article to complement these approaches by a simple online spatial correction of micro‐sensors. The principle is to use the reference measurements to correct the network of micro‐sensors. More precisely, by kriging only the measurements from micro‐sensors, the reference measurements are estimated; allowing to calculate a correction by kriging the differences, finally applied to the micro‐sensors. Then one can iterate this fundamental sequence of steps. Numerical experiments exploring the proposed algorithm by simulation and an application to a real‐world dataset are provided.
Characteristics of children on the autism spectrum who benefit the most from receiving intervention in inclusive versus specialised early childhood education settings
Authors: Vivanti Giacomo , Bent Catherine , Capes Kristy , Upson Shannon , Hudry Kristelle , Dissanayake Cheryl ,   The Victorian ASELCC Team
Published: September 2022

AbstractThis study examined the factors associated with social‐communicative outcomes for children on the autism spectrum receiving early intervention in inclusive versus specialised early childhood education programmes. Fifty‐eight preschool‐aged children randomly assigned to receive the Group‐Early Start Denver Model (G‐ESDM) in either inclusive or specialised (i.e., autism‐specific) classrooms across one calendar year showed similar outcomes at group mean‐level across measures of communication and social behaviour. We examined factors moderating outcomes across settings. Novel moderation analyses revealed that higher baseline social interest and nonverbal cognitive skills were associated with increased social communication gains for children in the inclusive classrooms, but not for those in specialised settings. Children who spend more time paying attention to people and have higher cognitive skills might benefit from receiving early intervention in inclusive settings, whilst these factors might be less relevant for children educated in specialised settings.
Two cases of cervical esophageal perforation treated by surgery
Authors: Yasui Tetsuro , Nishiyama Kazuo , Itoyama Shinsaku , Iwamoto Asano , Kogo Ryunosuke 
Published: September 2022

AbstractCervical esophageal perforation is rare, but it is associated with high mortality. We describe two patients with cervical esophageal perforation that required surgical treatment. In both cases, good outcomes were evenly achieved, despite the presence of risk factors. A prompt diagnosis and treatment with collaboration between a surgeon and a gastroenterologist are important.
Rare case of pneumoperitoneum in nonintubated COVID‐19 patient
Authors: Bohsas Haidara , Alzabibi Mhd Amin , Kashkash Fateh , Swed Sarya , Alibrahim Hidar , Sawaf Bisher , Ahmad Shoaib , Motawea Karam R. , Ahmed Eman Mohammed sharif 
Published: September 2022

AbstractWe report a rare case of a 50‐year‐old female patient with COVID‐19 presented to the emergency department where supplementary oxygen is delivered via noninvasive face mask ventilation. X‐ray imaging confirmed the existence of pneumoperitoneum. CT scan was not applicable due to the advanced status of the patient.
Pemphigus vulgaris with refractory gingival ulcerations, successfully treated with rituximab—A case report
Authors: Dolenc‐Voljč Mateja , Povšič Katja , Kučič Alja Cmok , Gašperšič Rok 
Published: September 2022

AbstractA patient presented with ulcerations of the buccal mucosae, palate and gingiva. A gingival biopsy confirmed the diagnosis as pemphigus vulgaris. Despite medication with systemic corticosteroids and mycophenolate mofetil, desquamative gingivitis persisted. Adjunct treatment with rituximab was therefore introduced. Regular follow‐ups revealed no inflammatory gingival changes even 6 years later.
Remarkable remission of a tumor‐stage mycosis fungoides on the scalp by single fraction palliative radiotherapy
Authors: Katano Atsuto 
Published: September 2022

AbstractFor tumor‐stage mycosis fungoides, systemic therapy in combination with skin‐directed local therapy is the mainstay of treatment. Here, we report a case where a tumor‐stage mycosis fungoides of the scalp showed a remarkable response to single fraction palliative radiotherapy.
A case of adult multisystem Langerhans histiocytosis successfully treated by smoking cessation and radiotherapy for bone lesion
Authors: Yamamoto Chie , Harada Taishi , Sawada Ryo , Sugimoto Takumi , Hayata Hiroki 
Published: September 2022

AbstractAn adult patient was diagnosed with multisystem Langerhans cell histiocytosis with lung and bone lesions. Her lung lesions improved after smoking cessation. Radiotherapy was performed for the bone lesions. Follow‐up assessment at 2 years after diagnosis showed no recurrence. Our case shows that remission is possible even without systemic treatment.
Operando DRIFT and In situ Raman Spectroscopic Studies on Aspects of CO2 Fischer‐Tropsch Synthesis Catalyzed by Bulk Iron Oxide‐Based Catalysts
Authors: Weiß Jana , Yang Qingxin , Bentrup Ursula , Kondratenko Evgenii V. , Brückner Angelika , Kubis Christoph 
Published: September 2022

AbstractHematite is a suitable precursor to obtain catalytically active iron (oxide) phases for CO2 Fischer‐Tropsch synthesis after a reductive pretreatment. As concluded from in situ Raman spectroscopy, in hydrogen atmosphere the transformation from α‐Fe2O3 to Fe3O4 is faster than the further reduction from Fe3O4 to Fe (metallic iron). The rate of these steps highly depends on the temperature. Starting from pure hematite, surface formate species are formed at a CO2/H2 gas mixture at elevated temperatures, observable by DRIFT‐spectroscopy. The exposure to CO2 and CO led to surface carbonate‐carboxylate surface species. Reduced samples with varying contents of Fe3O4 and Fe did not show any observable adsorbates at reaction conditions. The same behavior was found during the dosage of the single gases CO2 and CO to these reduced catalysts. The formation of carbonaceous species, detected by Raman spectroscopy, could indirectly hint to the occurrence of carbidation and was especially observed for a good performing catalyst with a medium reduction degree.
An Iodide‐Mediated Anodic Amide Coupling
Authors: Großmann Luca Marius , Beier Vera , Duttenhofer Lea , Lennartz Laura , Opatz Till 
Published: September 2022

AbstractInvited for the cover of this issue is the group of Till Opatz at the University of Mainz. The image depicts the electrochemical coupling of amines and carboxylic acids to form amides. Read the full text of the article at 10.1002/chem.202201768.
Polarity Inversion of Ga‐Polar GaN Surfaces by Exposing to Mg and NH3 in Metal–Organic Vapor Phase Epitaxy
Authors: Li Chengguo 
Published: September 2022

AbstractA metal–organic vapor phase epitaxy process of polarity inversion (PI) from Ga‐ to N‐polar is reported by exposing the Ga‐polar surface simultaneously to Mg and ammonia flows. This process differs from the conventional Mg heavy‐doping technique by intentionally predepositing a Mg‐rich thin layer on the Ga‐polar surface for PI. A full PI with a smooth surface in the subsequent GaN overgrowth is achieved by an exposure process for 900 s at 700 °C. Atomic force microscopy and piezo‐force microscopy characterizations reveal that the polarity change undergoes simultaneously with pyramid formation after ≈15 nm thick GaN overgrowth. The electron dispersion spectroscopy mapping of Mg indicates high Mg concentrations at the regrowth interface and in the PI domain boundary. A Mg‐rich thin layer is believed to cover the surface after the exposure process and release Mg dopants in the subsequent growth, leading to a high Mg incorporation in the GaN overlayer and therefore inducing PI. P‐type conduction with a hole concentration of ≈2.7 × 1017 cm−3 is achieved in the N‐polar GaN overlayer. It is also demonstrated that such a PI technique can be employed in the growth of a hybrid polarity structured ultraviolet‐light‐emitting diode with a reversed N‐polar contact layer on a Ga‐polar main body.
A Self‐Separating Multiphasic System for Catalytic Hydrogenation of CO2 and CO2‐Derivatives to Methanol
Authors: Diehl Thomas , Lanzerath Patrick , Franciò Giancarlo , Leitner Walter 
Published: September 2022

AbstractCatalytic conversion of CO2 and hydrogen to methanol was achieved in a self‐separating multiphasic system comprising the tailor‐made complex [Ru(CO)ClH(MACHO‐C12)] (MACHO‐C12=bis{2‐[bis(4‐dodecylphenyl)phosphino]ethyl}amine) in n‐decane as the catalyst phase. Effective catalyst recycling was demonstrated for the carbonate and the amine‐assisted pathway from CO2 to methanol. The polar products MeOH or MeOH/H2O generated from the catalytic reactions spontaneously formed a separate phase, allowing product isolation and catalyst separation without the need for any additional solvent. In the amine‐assisted hydrogenation of CO2, the catalyst phase was recycled over ten subsequent runs, reaching a total turnover number to MeOH of 19200 with an average selectivity of 96 %.
A figurational viewpoint of the complexity of policy enactment: An opportunity for agonistic dialogue?
Authors: Scanlon Dylan , MacPhail Ann , Calderón Antonio 
Published: September 2022

AbstractThe aim of this paper is to explore and provide an alternative theoretical viewpoint, informed by empirical studies, of the curriculum policy enactment process which spans across different curriculum policy spaces by drawing on figurational sociology. This paper constructs this alternative figurational viewpoint of the policy enactment process by drawing on curriculum policy and policy enactment literature. This viewpoint highlights how a curriculum policy can be (re‐)interpreted, (re‐)translated and (re‐)enacted by multiple, interconnected and interdependent (face‐to‐face and non‐face‐to‐face, recognised and unrecognised, past and present) relationships. We argue the need for agonistic dialogue between the stakeholders of the educational community and how his could lead to these stakeholders working together across curriculum policy spaces (e.g., curriculum development, teacher education, professional development) and on different aspects of ‘doing’ policy work. We encourage ourselves, and colleagues, to advocate for, support and provide evidence on the centrality of construction and enactment of curriculum policy in effective curriculum change.