bluuebunny/crossref_metadata_2025_split huggingface dataset:
The EWAS Catalog: a database of epigenome-wide association studies
Authors: Battram Thomas , Yousefi Paul , Crawford Gemma , Prince Claire , Sheikhali Babaei Mahsa , Sharp Gemma , Hatcher Charlie , Vega-Salas María Jesús , Khodabakhsh Sahar , Whitehurst Oliver , Langdon Ryan , Mahoney Luke , Elliott Hannah R. , Mancano Giulia , Lee Matthew A. , Watkins Sarah H. , Lay Abigail C. , Hemani Gibran , Gaunt Tom R. , Relton Caroline L. , Staley James R. , Suderman Matthew 
Published: May 2022

Epigenome-wide association studies (EWAS) seek to quantify associations between traits/exposures and DNA methylation measured at thousands or millions of CpG sites across the genome. In recent years, the increase in availability of DNA methylation measures in population-based cohorts and case-control studies has resulted in a dramatic expansion of the number of EWAS being performed and published. To make this rich source of results more accessible, we have manually curated a database of CpG-trait associations (with p<1x10-4) from published EWAS, each assaying over 100,000 CpGs in at least 100 individuals. From January 7, 2022, The EWAS Catalog contained 1,737,746 associations from 2,686 EWAS. This includes 1,345,398 associations from 342 peer-reviewed publications. In addition, it also contains summary statistics for 392,348 associations from 427 EWAS, performed on data from the Avon Longitudinal Study of Parents and Children (ALSPAC) and the Gene Expression Omnibus (GEO). The database is accompanied by a web-based tool and R package, giving researchers the opportunity to query EWAS associations quickly and easily, and gain insight into the molecular underpinnings of disease as well as the impact of traits and exposures on the DNA methylome. The EWAS Catalog data extraction team continue to update the database monthly and we encourage any EWAS authors to upload their summary statistics to our website. Details of how to upload data can be found here: http://www.ewascatalog.org/upload. The EWAS Catalog is available at http://www.ewascatalog.org.
Practice-Oriented Approaches in Professional Orientation of Schoolchildren
Authors: Frolova Svetlana , Shtan'ko I. 
Published: May 2022

A number of state documents in the field of education emphasize the importance of organizing an effective system of career guidance for students. The relevance of this work is due to several reasons, one of which is the strengthening of the dynamics of the labor market and the market of professions. Today, futurologists find it difficult to say which of the professions will be in demand in the future. Today's students should have a clear understanding of what the expression "lifelong education" means and be ready to change their profession.
One of the modern approaches to creating an effective career guidance system is the actual approach, that is, the orientation of the student to the choice of a profession for the "here and now", but at the same time, teachers should warn about a possible reorientation. All this determines the acuteness of the problem of pedagogical support of professional self-determination of students.
In addition, it is quite obvious that the socio-economic development of the country depends on the correct choice of a profession by school graduates, since this choice determines the motivation to receive a quality professional education.
The authors of the article believe that for effective career guidance, an educational organization should use all resources (resource approach), in particular, the resources of additional education.
The authors' material may be useful for teachers working on the creation of a career guidance system based on modern practice-oriented approaches.
Structural Equation Model (SEM) dalam Pemodelan Kemiskinan di Pulau Sumatera
Authors: Zebua Hasrat Ifolala , Harefa Geni Andalria 
Published: May 2022

<p align="justify">Poverty is a serious issue that must be addressed immediately by countries in the world, including Indonesia. The Indonesian government has implemented a variety of poverty reduction projects, such as providing education and health insurance. The rising poverty rate is due to the poor quality of education and health care. On Sumatra, there are 5,83 million poor people or 22,06 percent of the total number of poor people in Indonesia. This statistic appears to be quite large, and the government should be concerned about it. Factors causing poverty such as education and health are latent variables that cannot be measured directly. The suitable statistical method used is Structural Equation Model (SEM). In SEM analysis, there are three types of model fit tests: measurement model fit with Confirmatory Factor Analysis (CFA), overall model fit, and structural model fit. The results indicated that the model was fit or suitable for the model's tests. From the SEM model that was formed, it was found that health had a negative and significant effect on poverty and education did not have a significant effect on poverty and 77 percent of the variation in poverty could be explained by the SEM model that was formed.</p><p><strong>Keywords</strong><strong>: </strong>poverty; education; health; SEM; CFA</p>
Micro-opto-electro-mechanical systems accelerometer based on the Talbot effect of double-layer diffraction gratings
Authors: Jin Liming , Wang Ce , Jin Li , Chen Wenqing , Xu Haodong , Cui Min , Li Mengwei 
Published: May 2022

In this paper, we present the design, fabrication, and test of a micro-opto-electro-mechanical systems (MOEMS) accelerometer based on the Talbot effect of double-layer diffraction gratings. The detection of acceleration is realized by using the highly sensitive displacement characteristic of Talbot imaging of near-field diffraction with double-layer gratings. For the purpose of obtaining optimal contrast of the optical interferometric detection, the parameters of the gratings are optimized by the finite-difference time-domain (FDTD) simulation. The experimental results indicate that this MOEMS accelerometer with the proposed design can achieve a resolution of 246 µg, sensitivity of 6.1 V/g, and bias stability of 0.02 mg. The proposed accelerometer can be operated at higher accelerations (

∼

80

g

), which shows significant potential for being used in applications that require detection of strong and fast vibrations, especially in vibration sensing of vehicles and geophysical seismic sensing in real time.
Die Einflüsse von Arbeitsbelastung auf die Arbeitsqualität agiler Software-Entwicklungsteams
Authors: Sanden Christian , Karnowski Kira , Steinke Marvin , Neumann Michael , Linke Lukas 
Published: May 2022

ZusammenfassungDurch die Covid 19 Pandemie und der damit einhergehenden Effekte auf die Arbeitswelt ist die Belastung der Mitarbeitenden in einen stärkeren Fokus gerückt worden. Dieser Umstand trifft unter anderem durch den umfassenden Wechsel in die Remote Work auch auf agile Software-Entwicklungsteams in vielen Unternehmen zu. Eine zu hohe Arbeitsbelastung kann zu diversen negativen Effekten, wie einem erhöhten Krankenstand, dem Wohlbefinden der Mitarbeitenden oder reduzierter Produktivität führen. Es ist zudem bekannt, dass sich die Arbeitsbelastung in der Wissensarbeit auf die Qualität der Arbeitsergebnisse auswirkt. Dieser Forschungsbeitrag identifiziert potenzielle Faktoren der Arbeitsbelastung der Mitglieder eines agilen Software-Entwicklungsteam bei der Otto GmbH & Co KG. Auf der Grundlage der Faktoren präsentieren wir Maßnahmen zur Reduzierung von Arbeitsbelastung und erläutern unsere Erkenntnisse, die wir im Rahmen eines Experiments validiert haben. Unsere Ergebnisse zeigen, dass bereits kleinteilige Maßnahmen, wie das Einführen von Ruhearbeitsphasen während des Arbeitstages, zu positiven Effekten bspw. hinsichtlich einer gesteigerten Konzentrationsfähigkeit führen und wie sich diese auf die Qualität der Arbeitsergebnisse auswirken.
Predictors of time to recovery and non-response during outpatient treatment of severe acute malnutrition
Authors: Kangas Suvi T. , Salpéteur Cécile , Nikièma Victor , Ritz Christian , Friis Henrik , Briend André , Kaestel Pernille 
Published: May 2022

Background
Every year, over 4 million children are treated for severe acute malnutrition with varying program performance. This study sought to explore the predictors of time to recovery from and non-response to outpatient treatment of SAM.

Methods
Children with weight-for-height z-score (WHZ) <-3 and/or mid-upper arm circumference (MUAC) <115 mm, without medical complications were enrolled in a trial (called MANGO) from outpatient clinics in Burkina Faso. Treatment included a weekly ration of ready-to-use therapeutic foods. Recovery was declared with WHZ ≥-2 and/or MUAC ≥125 mm, for two weeks without illness. Children not recovered by 16 weeks were considered as non-response to treatment. Predictors studied included admission characteristics, morbidity and compliance during treatment and household characteristics. Cox proportional hazard models were fitted and restricted mean time to recovery calculated. Logistic regression was used to analyse non-response to treatment.

Results
Fifty-five percent of children recovered and mean time to recovery was eight weeks while 13% ended as non-response to treatment. Independent predictors of longer time to recovery or non-response included low age, being admitted with WHZ <-3, no illness nor anaemia at admission, illness episodes during treatment, skipped or missed visits, low maternal age and not practising open defecation. Eighty-four percent of children had at least one and 59% at least two illness episodes during treatment. This increased treatment duration by 1 to 4 weeks. Thirty-five percent of children missed at least one treatment visit. One missed visit predicted 3 weeks longer and two or more missed visits 5 weeks longer treatment duration.

Conclusions
Both longer time to recovery and higher non-response to treatment seem most strongly associated with illness episodes and missed visits during treatment. This indicates that prevention of illnesses would be key to shortening the treatment duration and that there is a need to seek ways to facilitate adherence.
Agronegócio Brasileiro: Desafios e Oportunidades para a Atuação do Administrador / Brazilian Agribusiness: Challenges and Opportunities for the Action of the Administrator
Authors: Sousa Josiano Cesar De , Sena Lucas Henrique Da Silva 
Published: May 2022

Resumo: Esse trabalho surgiu da necessidade de se investigar a importância do Administrador para a gestão das atividades no agronegócio e foi embasado na seguinte problemática: quais são os principais desafios e oportunidades encontrados pelos gestores à frente de empresas que atuam no agronegócio brasileiro? Para responder a esse questionamento, o presente artigo foi elaborado com o objetivo de apontar os principais desafios e as oportunidades que surgem para a atuação do administrador a frente de organizações que atuam no agronegócio brasileiro. Trata-se de uma pesquisa bibliográfica exploratória e descritiva de caráter qualitativo, com o intuito de discorrer sobre os desafios que compõem os processos do agronegócio assim como apontar a contribuição do administrador para a melhoria destes processos. Nos resultados, constatou-se que os gestores encontram desafios quanto a gestão de custos, comunicação empresarial, falta de mão de obra qualificada, logística e infraestrutura; dai surgem as oportunidades, gestão da qualidade, gestão de custo, gestão de controle da produção, gestão de logística, gestão da cadeia de suprimentos.Palavras-Chave: Agronegócio. Desafios. Oportunidades.Abstract: This work arose from the need to investigate the importance of the Administrator for the management of activities in agribusiness and was based on the following problem: what are the main challenges and opportunities encountered by managers at the head of companies that operate in Brazilian agribusiness? To answer this question, this article was prepared with the objective of pointing out the main challenges and opportunities that arise for the performance of the administrator in front of organizations that work in Brazilian agribusiness. This is an exploratory and descriptive bibliographic research of a qualitative nature, with the aim of discussing the challenges that make up the agribusiness processes as well as pointing out the administrator's contribution to the improvement of these processes. In the results, it was found that managers face challenges regarding cost management, business communication, lack of qualified labor, logistics and infrastructure. Thus arise opportunities for quality management, cost management, production control management, logistics management, supply chain management.Keywords: Agribusiness. Challenges. Opportunities.
Liderança Feminina: Os Desafios das Mulheres na Liderança Organizacional / Female Leadership: The Challenges of Women in Organizational Leadership
Authors: Silva Verislania Silva e , Rodrigues Luciana Da Luz 
Published: May 2022

Resumo: A liderança feminina na era moderna tem atraído vários graus de interesse no mundo organizacional e no meio acadêmico. Ao longo da história, as mulheres têm tido uma jornada difícil que merece atenção especial. A participação das mulheres em posições de liderança em pequenas, médias e grandes empresas no país aumentou significativamente. A liderança não se trata apenas de dar ordens, mas sobretudo de trabalhar nas relações interpessoais, o que pode ser um fator dominante nesta conquista feminina. A metodologia aplicada neste estudo foi um estudo bibliográfico e exploratório baseado em páginas da web, livros, artigos e periódicos. O objetivo geral deste estudo foi destacar a importância da liderança feminina na organização. Os resultados mostraram que um novo modelo de gestão feminina está surgindo e começamos a perceber que, para lidar com uma organização altamente competitiva, é necessário utilizar cada vez mais técnicas ágeis, que estão gradualmente ganhando seu lugar e funcionando em grandes organizações. Portanto, conclui-se que a liderança feminina tem um grande potencial para ganhar importância na organização e que é capaz de substituir a liderança masculina nas diferentes atividades que deseja realizar. Palavras-chave: Organização. Liderança feminina. Motivação. Abstract: Female leadership in the modern era has attracted varying degrees of interest in the organizational world and in academia. Throughout history, women have had a difficult journey that deserves special attention. The participation of women in leadership positions in small, medium, and large companies in the country has increased significantly. Leadership is not only about giving orders, but mainly about working on interpersonal relationships, which can be a dominant factor in this female achievement. The methodology applied in this study was a bibliographic and exploratory study based on web pages, books, articles, and periodicals. The overall objective of this study was to highlight the importance of female leadership in the organization. The results showed that a new model of female management is emerging, and we began to realize that in order to deal with a highly competitive organization, it is necessary to use more and more agile techniques, which are gradually gaining their place and functioning in large organizations. Therefore, it is concluded that female leadership has a great potential to gain importance in the organization and that it can replace male leadership in the different activities it wants to perform.Keywords: Organization. Female leadership. Motivation.
Governança no Setor Público: Um Estudo sobre as Atividades da Câmara Municipal de Dormentes/PE / Governance in the Public Sector: A Study on the Activities of the City Council of Dormentes/PE
Authors: Coelho Bruno De Macedo , Aquino Vanessa De Almeida , Pinto André Costa , Ceolin Alessandra Carla 
Published: May 2022

Resumo: O estudo analisa as atividades de governança realizadas pelos vereadores de Dormentes/PE, no que tange aos seus projetos de leis e decretos, no período 2017 a 2020.Destaca-se a importância em abordar as atividades legislativas impulsionadas não apenas pela necessidade de solução de demandas da população, mas como importantes elementos da conexão e trocas que se estabelecem entre os representantes políticos, da sociedade e o poder executivo, as quais refletem-se na qualidade de vida dos seus munícipes. Trata-se de uma pesquisa descritiva e com abordagem qualitativa, que analisou projetos, decretos e leis; Carta de Serviço ao Usuário da Câmara Municipal, dentre outros. Os principais resultados apontam que o poder legislativo é responsável por diversas atribuições, sendo de sua competência legislar em consonância com interesse público, fiscalizar o poder executivo, e principalmente, destaca-se a representação da sociedade. Salienta-se que as atividades desenvolvidas precisam atender de forma efetiva as necessidades dos cidadãoPalavras-chave: Acesso à Informação, Gestão Pública, Accountability, e-SIC, Transparência. Abstract: The study analyzes the governance activities carried out by the councilors of Dormentes/PE, regarding their draft laws and decrees, from 2017 to 2020. The importance of addressing legislative activities driven not only by the need to solve the population's demands is highlighted, but as important elements of the connection and exchanges that are established between political representatives, society, and the executive power, which are reflected in in the quality of life of its citizens. This is descriptive research with a qualitative approach, which analyzed projects, decrees and laws, City Council User Service Letter, among others. The main results point out that the legislature is responsible for several attributions, being its competence to legislate in line with the public interest, supervise the executive power, and mainly, the representation of society. It should be noted that the activities developed need to effectively meet the needs of citizens.Keywords: Access to Information, Public Management, Accountability, e-SIC, Transparency.
“Não, eu só rezo em criança”: Benzedeiras e Construções epistemológicas em saúde no Cariri cearense / “No, I only pray in children”: Faith healing and epistemological Constructions in health in Cariri cearense
Authors: Feitosa Pedro Walisson Gomes , Maia Maria Andrezza Gomes , Ribeiro Nayana Freitas Vieira , Leite Victória Monalisa Batista de Freitas , Freitas Neta Maria Stella Batista de , Pinheiro Sally De França Lacerda 
Published: May 2022

Resumo: A benzeção realiza um papel importante nas práticas populares em saúde, tornando-se em um patrimônio imaterial tanto para aqueles indivíduos que a praticam quanto para os que se beneficiam dela. Nesse sentido, o presente trabalho tem como finalidade relatar as experiências dos estudantes de Medicina da Universidade Federal do Cariri em um projeto de registros epistêmicos de benzedeiras no interior do nordeste brasileiro. Tendo levado a cabo o projeto, foi possível consignar a relevância da passagem de conhecimentos através das gerações de benzedeiras na região, mostrando a necessidade de valorizar e preservar os saberes que viabilizam a realização das práticas populares em saúdePalavras-chave: Saúde popular; Cultura; Epistemologia Abstract: Faith healing plays an important role in popular health practices, becoming an intangible heritage both for those who practice it and for those who benefit from it. In this sense, the present work aims to report the experiences of medical students from the Federal University of Cariri in a project of epistemic records of traditional healers in the interior of northeastern Brazil. Having carried out the project, it was possible to chronicle the relevance of passing on knowledge through generations of traditional healers in the region, showing the need to value and preserve the knowledge that enables the realization of popular health practices.Keywords: Popular health; Culture; Epistemology.
Modeling and simulation sedimentation process using finite difference method
Authors: Naser Mohammed Abed , Abdulrazzaq Khalid Adel 
Published: May 2022

Abstract
The goal of this research is to develop a numerical model that can be used to simulate the sedimentation process under two scenarios: first, the flocculation unit is on duty, and second, the flocculation unit is out of commission. The general equation of flow and sediment transport were solved using the finite difference method, then coded using Matlab software. The result of this study was: the difference in removal efficiency between the coded model and operational model for each particle size dataset was very close, with a difference value of +3.01%, indicating that the model can be used to predict the removal efficiency of a rectangular sedimentation basin. The study also revealed that the critical particle size was 0.01 mm, which means that most particles with diameters larger than 0.01 mm settled due to physical force, while most particles with diameters smaller than 0.01 mm settled due to flocculation process. At 10 m from the inlet zone, the removal efficiency was more than 60% of the total removal rate, indicating that increasing basin length is not a cost-effective way to improve removal efficiency. The influence of the flocculation process appears at particle sizes smaller than 0.01 mm, which is a small percentage (10%) of sieve analysis test. When the percentage reaches 20%, the difference in accumulative removal efficiency rises from +3.57% to 11.1% at the AL-Muthana sedimentation unit.
The 26th Scientific Conference of the Society on NeuroImmune Pharmacology: College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN, June 1-3, 2022
Authors: Kumar Santosh , Dash Chandravanu , Pendyala Gurudutt , Yelamanchili Sowmya V. , Maggirwar Sanjay B. , Bidlack Jean M. , Chang Sulie L. 
Published: May 2022

Abstract
The 26th Scientific Conference of the Society on NeuroImmune Pharmacology (SNIP) at the University of Tennessee Health Science Center in Memphis, Tennessee, June 1-3, 2022, is SNIP’s first full-fledged meeting in person since the onset of the coronavirus disease-19 pandemic. The three-day meeting encompasses a variety of activities that include a pre-conference session, many scientific sessions (eight symposia and two plenary lectures), two special talks, a poster session, oral talks, a mentoring session for early career investigators, a diversity and inclusion SNIP committee session, a business meeting, and an award session. A conference summary, detailed program agenda, accepted poster abstracts, and presentation abstracts are included in this brief report published in advance of the meeting.