bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Bacteria Addition Study to Batik Wastewater Industries In pH Performance, and Removal of Ammonia and COD
Authors: Gunawan M , Wikaningrum T 
Published: April 2022

Abstract
The production of batik generates a large volume of wastewater with complex nature and characteristics such as high temperature, pH, BOD, COD, and TSS. In Jababeka Industrial Estate, Wastewater from batik industries is treated by going through a facultative equalization tank before going to the next treatment units. Hypothetically, by optimizing the facultative equalization tank, it will improve the effluent quality and increase COD and Ammonia’s removal efficiency. This research used 4 microbial products that are commercially available and can be applied easily in real-life operating conditions. The study aimed to determine the effect of bacteria addition and its removal efficiency for batik wastewater effluent from batik industries in Jababeka Industrial Estate. the parameters measured were pH, concentration of COD and ammonia. The addition of bacteria reduced COD and Ammonia concentration in the wastewater and changed the wastewater’s pH and color. The result indicates that for high COD and ammonia loads, the M-Aerobic bacteria is the best type of bacteria with a removal efficiency of 63.39% and 99%, respectively. However, ANOVA analysis indicates that there is no statistically significant difference between the treatment groups. It is recommended for this experiment to be repeated in a continuous reactor.
The Effect Of High Salt Stress On The Agronomic, Chlorophyll Content, and Yield Characteristics Of Several Rice Varieties
Authors: Nasrudin N , Isnaeni S , Fahmi P 
Published: April 2022

Abstract
Salinity caused losses to rice farmers because it becomes an obstacle to rice growth and decrease a productivity. The use of superior rice variety is an effort to rice produce optimally. In order to examined and compared several rice varieties to salinity stress based on agronomic, chlorophyll content, and yield characters. A factorial completely randomized design was used in this study, the first factor was rice varieties consisting of Banyuasin, Inpari 30, and Inpari 34, while the second factor was salt concentration consisted of non-saline and 8 dS m−1. There were six combination treatments and repeated three times. The results showed that Inpari 34 had a tallest plant compared to other varieties in non-saline and 8 dS m−1. Banyuasin and Inpari 30 had wider leaves, the number of panicles per clump, and higher harvest index compared to Inpari 34, however Inpari 34 produce more grain per panicle compared of two varieties. Inpari 30 grown in 8 dS m−1 had a highest chlorophyll a-b compared to the other treatment. Inpari 30 had the best agronomic performance indicated by increases of leaf area, number of panicles per clump, harvest index, and content of chlorophyll a-b.
Optimization Of Rubber Farmer Revenue In Relation To Rainfall Fluctuations In South Sumatera
Authors: Nugraha I S , Alamsyah A , Aji M , Ardika R , Cahyo AN 
Published: April 2022

Abstract
The yield of rubber plantation has a strong correlation with the amount of rainfall. Rainfall pattern in South Sumatera is not distributed evenly round the year, hence the rubber plantation production is fluctuated, especially at the peak of wet and dry season. This research aimed to determine the revenue that can be optimized by using rain guard to save yield loss on wet season as well as by adoption of rubber drought tolerant clone to increase yield on dry season. This research was conducted in Indonesian Rubber Research Institute by collecting weather data as well as rubber production in Indonesian Rubber Research Institute experimental field in the last eight years (2013 – 2021). The results of this study showed that optimal yield was achieved in wet season although some tapping days were lost due to rainfall. On the contrary, the yield was reduced to 50% on the dry season. The average of potential revenue that can be optimized during wet and dry season was equal to IDR 5,050,488/ha/year and IDR5,106,630/ha/year respectively. This potential revenue can be optimized by installing rain guard on wet season as well as adoption of rubber drought tolerance clone.
Fruit Fly Attack On Intercropping Plants
Authors: Hapidin I , Hidayat C , Firmansyah E 
Published: April 2022

Abstract
Fruit fly was a major pest in red pepper plant. This pest can cause minor to serious damage if not controlled. There are several fruit fly species which known in Indonesia. The objectives of this research was to know the species and population abundance of fruit fly on intercropping plants area in Garut distric, West Java. The modified Steiner trap was used in several areal spot to collect this pest. and to identified the species, the delta Intkey software used. The result showed that fluctuation of population abundance occurred in the field and the result of species identification showed that all of the fruit fly which trapped was Bactrocera dorsalis.
The Study of Ammonia Removal in Wastewater Using Natural Granular Zeolite Filter
Authors: Yurika N , Wikaningrum T 
Published: April 2022

Abstract
The wastewater generated from all industries should discharge into the estate sewerage system, which flows to the centralized wastewater treatment plant (WWTP) of Jababeka Industrial Estate. One of the wastewater parameter problem is ammonia. This research to study ammonia removal using natural granular Zeolite filter in wastewater by variations of granular size and different volume (expressed as height) of Zeolite to meet the required standard. This experiment was carried out using artificial samples of 75 mg/L of ammonia in the laboratory scale that indicate with APHA, AWWA, and WEF, no 4500-NH3 as the analysis method. The result proved that using a natural Zeolite filter could reduce the ammonia concentration, with the efficiency of removal was 91.6%. The 0.5cm granular size at the height of 5 cm (289.25 cm3 of Zeolite) with a result of 6.25 mg/L after 120 minutes and the 0.5 cm grain size at the height of 6 cm (347.81 cm3 of Zeolite) can achieve the same performance after a shorter time of 60 minutes. Both results were below the ammonia’s Jababeka Wastewater Quality Standard of 10 mg/L.
Colonization and Establishment of Exallomochlus hispidus (Morrison) (Hemiptera: Pseudococcidae) From the Field Colony to Laboratory Colony
Authors: Indarwatmi M 
Published: April 2022

Abstract
The mealybug Exallomochlus hispidus is a polyphagous pest, some of its hosts are important fruits. This pest control research requires laboratory colonies in large numbers. The purpose of the research was to study the colonization and establishment of E. hispidus from the field colony into laboratory colony. E. hispidus was collected from infected mangosteen fruit. Kabocha was put in a plastic container containing mealybugs in the mangosteen fruit. Observations on the number of mealybugs that moved from mangosteen to kabocha were carried out every 24 hours for 72 hours. Establishment parameters observed were life cycle, adult longevity, and reproduction for three generations. The results showed that on the 24 hours, more mealybugs moved than on the 48 and 72 hours. In the 2nd generation of the laboratory colony, it shows that the life cycle was shorter, the adult longevity was longer and the reproduction was higher than field and 1st generation. The success of laboratory colonization and establishment will support the success of the experiments.
OR1. A novel double heterozygote variation of NKX2-5 gene in adult patients with atrial septal defect
Authors: Rozqie R , Dinarti L K , Mumpuni H 
Published: April 2022

Abstract

Background and Aim
It is still unclear whether the NKX2-5 variant is involved in congenital heart disease patients in Indonesia. Here, we investigate the genetic variation of NKX2-5 in adult atrial septal defect (ASD) patients at RSUP Dr Sardjito Yogyakarta, Indonesia.

Methods and Results
We screened 97 patients with ASD for genetic variations of NKX2-5. DNA samples were extracted from venous blood. The whole two coding exons of the NKX2-5 gene were amplified by PCR and sequenced using the Sanger method. The sequence was compared with the reference genome taken from NCBI using SerialCloner software.
We identified three NKX2-5 genetic variants: c.63 A&gt;G (rs2277923) at exon 1, c.413 G&gt;A (rs1366528649) and c.561G&gt;A (rs767559311) at exon 2. The variation in rs2277923 was detected in 83 patients (85.6%), including 41 subjects (42.3%) with heterozygous A&gt;G and 42 subjects (43. 3%) with homozygous A&gt;G. However, it has a similar amino acid sequence. The variant of rs1366528649 and rs767559311 were heterozygous and found in the same locus (double heterozygous variation). Interestingly, rs1366528649 and rs767559311 were only identified in familial ASD (3 patients, 3,1%). The rs1366528649 variant replaces arginine (a basic amino acid) with glutamine (an acidic amino acid). Meanwhile, the rs767559311 variant substitutes glutamine with histidine (a basic amino acid).

Conclusion
We discovered a novel double heterozygote variation of the NKX2-5 gene (rs1366528649 and rs767559311) and may contribute to familial ASD risk. Moreover, rs2277923 is the most common variation in ASD patients in Indonesia.
OR4. Agreement between Transthoracic Echocardiography and Surgical Measurements of the Tricuspid Annulus Diameter
Authors: Nugroho S S , Nugroho M A , Ardhianto P , Fatah S , Sodiq M A , Sobirin M A 
Published: April 2022

Abstract

Aims
The tricuspid annulus dilatation is an indication for tricuspid repair concomitant with mitral surgery. The distance between anteroseptal and anteroposterior commissure represents the direction of dilatation provided by surgical measurements. However, none of the standard views of two-dimensional transthoracic echocardiography (2D-TTE) intersect that plane and there is still a lack of study regarding the tricuspid annulus measurements by three-dimensional transthoracic echocardiography (3D-TTE). Therefore, this study aims to determine the agreement between the tricuspid annulus diameter measurement by transthoracic echocardiography and surgical measurement.

Methods and Results
40 patients were included. Measurements of tricuspid annulus diameter by 2D-TTE and 3D-TTE were performed before surgery in parasternal right ventricle inflow (PRVI), parasternal short axis (PSAX), apical 4-chambers (A4C), and multiplanar analysis 3D-TTE views. Surgical measurements were performed during surgery. Agreement between the echocardiography and surgical measurements was analyzed using Bland-Altman and intraclass correlation analysis. Mean difference ± standard deviation (limits of agreement) and ICC of PRVI 2D-TTE vs surgical measurement were 1.35±5.02 mm (-8.48 - 11.18 mm), ICC 0.89, p &lt; 0.001; PSAX 2D-TTE vs surgical measurement were 1.35±5.23 mm (-8.90 - 11.60 mm), ICC 0.88, p &lt; 0.001; A4C 2D-TTE vs surgical measurement were 1.33±3.69 mm (-5.91 - 8.56 mm), ICC 0.93, p &lt; 0.001; septolateral diameter 3D-TTE vs surgical measurements were 1.42±4.41 mm, (-7.22 - 10.06 mm), ICC 0.90, p &lt; 0.001; anteroposterior diameter 3D-TTE vs surgical measurements were -2.695±7.43 mm (- 17.26 - 11.87 mm), ICC 0.68, p &lt; 0.001.

Conclusion
A4C 2D-TTE and septolateral diameter 3D-TTE measurement have an excellent agreement with surgical measurement.
OR5. Ambulatory blood pressure profile among uncontrolled hypertensive patients in Indonesian Army Central Hospital Gatot Soebroto: an initial study
Authors: Pujowaskito P , Tartila T S , Jannah F D K , Tafriend N A 
Published: April 2022

Abstract

Aims
Ambulatory blood pressure monitoring (ABPM) has an important role in the evaluation of blood pressure (BP) control, particularly in uncontrolled hypertension, to optimize therapy. This study assessed ambulatory blood pressure profiles among patients with uncontrolled hypertension in Indonesian Army Central Hospital Gatot Soebroto.

Methods and Results
During our initial study from February to May 2021, a total of 40 patients with uncontrolled hypertension from Cardiac Outpatient Clinic, Indonesian Army Central Hospital Gatot Soebroto were recruited. Uncontrolled hypertension was defined as systolic BP &gt;140 mmHg and or diastolic BP &gt;90 mmHg in patients taking antihypertensive treatment. The population was 67.5% female, aged 63.18 + 11.82 years old, with an average office systolic BP of 157.5 + 24.41 mmHg and diastolic BP of 80.55 + 15.37 mmHg. All patients underwent ABPM within a week after the index office visit to evaluate 24-hour BP, BP variability, and white coat effect. The average 24-hour systolic and diastolic BP of the population was 137.40 + 16.7 mmHg and 78.55 + 12.94 mmHg respectively. Reverse-dipper was the most frequent pattern presented (47.5%). White coat effect was found in 47.5% of subjects and 27.5% of the total population were classified as white coat uncontrolled hypertension.

Conclusion
A marked discrepancy was found between ambulatory blood pressure profiles with office BP among patients with uncontrolled hypertension. Nearly half of the population had white coat effect, which revealed the importance of blood pressure control evaluation by ABPM to prevent overtreatment.
OR6. Ankle-brachial index is associated with carotid intima-media thickness in type 2 diabetes mellitus patients
Authors: Hariadi G B Putra , Ismail M T , Hariawan H 
Published: April 2022

Abstract

Background and Aims
Atherosclerosis and its complications occur more rapidly in diabetes mellitus. Early detection remains a challenge. Carotid intima-media thickness (CIMT) has been used widely and validated marker for detecting subclinical atherosclerosis. The limitation of this examination is operator dependence. Meanwhile, ankle-brachial index (ABI) examination is easier and widely available. This study is aimed to evaluate correlation ABI and CIMT in type 2 diabetes mellitus patients.

Method and Results
We conducted cross-sectional study in vascular outpatient clinic of Dr. Sardjito Hospital. Fifty-one patients were taken by purposive sampling. An interview, hematological parameters, lipid profiles, anthropometric, ABI, and CIMT measurement were performed. ABI was measured by doppler ultrasound, meanwhile an ultrasound examination of both common carotid artery was done to obtain the CIMT. Subjects were 49.02% females and 50.98% males, with mean age 59.22 ± 8.8 years old. The percentages of hypertension, dyslipidemia, smoking, obesity, metabolic syndrome, coronary artery disease, congestive heart failure, and chronic kidney disease were 60.8%, 51%, 27.5%, 52.9%, 72.5%, 31.4%, 9.8%, and 9.8%, respectively. Bivariate analysis showed mean ABI in the presence of mean CIMT ≥1mm and/or carotid plaque were lower (1.05±0.17 vs 1.16±0.08, p = 0.016). Proportions mean and maximum CIMT ≥1mm were 15.7% and 33.3%, respectively. Pearson’s correlation showed ABI was negatively correlated with mean CIMT and maximum CIMT (r=-0.334, p = 0.017; r=-0.299, p = 0.033).

Conclusion
Ankle-brachial index is negatively correlated with carotid intima-media thickness. Therefore, in limited facility, ABI examination might be performed for predicting subclinical atherosclerosis.
OR9. Association between Echocardiographic Pulmonary to Left Atrial Ratio (ePLAR) and Pulmonary Vascular Resistance in Patients with Adult Congenital Heart Diseases
Authors: Baskoro A P , Umamy K N , Nursidiq A A , Purwaningtyas N , Wasyanto T 
Published: April 2022

Abstract

Background and Aims
Echocardiographic pulmonary to left atrial ratio (ePLAR) is a new echocardiographic valuable parameter for distinguishing precapillary and postcapillary PH. This study aims to determine the association between ePLAR and PVR in patients with ACHD.

Methods and Results
A total of 42 patients with ACHD who underwent RHC at Dr Moewardi General Hospital between May 2019 to February 2021 were included in this retrospective observational study. Transthoracic echocardiography and RHC were performed in all patients. The ePLAR then compared between the patient with PVR &lt;5 WU and PVR &gt;5 WU. There were 15 patients (median age 37.00 (24.00 - 64.00) in PVR &lt;5WU group and 10 patients (median age 29.00 (24.00 – 49.00) in PVR &gt;5 WU group. Mean ePLAR in PVR &lt;5 WU group was 0.28 ±0.13 and 0.52 ±0.23 in patients with PVR &gt;5 WU group. Statistical analysis has shown significant difference of ePLAR between the PVR &lt;5 WU group and the PVR &gt;5 WU group, p &lt; 0.003. The ePLAR cut off value for PVR was 0.341 with sensitivity of 90.0% and specificity of 73.3% (AUC 0.827; p &lt; 0.007). Patients with ePLAR value of &gt;0.341 will significantly show higher PVR by RHC of &gt; 5 WU (OR 24.7, (95% CI 2.333-262.5), p &lt; 0.004).

Conclusion
Our study shows the association between ePLAR and PVR in patients with ACHD. The ePLAR value of &gt;0.341 can predict PVR &gt;5 WU with good sensitivity and specificity.
OR11. Association between T peak-T end interval and mortality in patient with complex coronary lesion scheduled for Coronary Artery Bypass Graft procedure
Authors: Pradipta V R , Perdana A , Abidin A Z , Sidiek A , Ardhianto P 
Published: April 2022

Abstract

Aim
Patient with complex coronary lesion face a mortality risk caused by sudden cardiac death (SCD). The Tpeak-Tend (TpTe) interval is a measure of dispersion of ventricular repolarization. Our aim is to investigate the relationship between the TpTe interval in patient’s resting 12-lead electrocardiogram (ECG) and the mortality incidence of patient waiting for Coronary Artery Bypass Graft (CABG) procedure.

Methods and result
Total of 175 patient scheduled for CABG procedure between January 2018 to December 2020. ECG was taken from medical record, interval of TpTe is calculated in V2 lead with tangent method ECG analysis. Association between variables analysed with Pearson chi-square test.
Baseline characteristic showed age 58.7 ± 6.8 years old, syntax score 30.66 ± 4.0 and left ventricle ejection fraction 47.8% ±14.4. There is significant association between prolonged TpTe interval (&gt;85 ms) and mortality incidence before CABG with odds ratio 3.821 (95% CI 1.727 – 8.454; p = 0.001).

Conclusion
TpTe interval is a feasible parameter that associate with the mortality in patient with complex coronary disease.
OR16. Circulating Interleukin-6 correlates with Left Ventricular Ejection Fraction in ST-Segment Elevation Myocardial Infarction
Authors: Samalo D , Fadil M 
Published: April 2022

Abstract

Background and Aim
ST-Segment Elevation Myocardial Infarction (STEMI) is a life-threatening condition caused by sudden blockage of infarct-related artery and is one of the major causes of death worldwide. Interleukin-6 (IL-6) is known to have a role in the development of atherosclerotic plaque that occurs in STEMI. This inflammatory response was associated with Left Ventricular Ejection Fraction (LVEF) disruption which can directly increase morbidity and mortality of STEMI. This study aims to determine the relationship between IL-6 with LVEF in STEMI patients.

Methods and Results
This is a cross-sectional study conducted with a total of 20 STEMI patients. IL-6 was measured at hospital admission and LVEF was assessed within 6 months post Primary Percutaneous Coronary Intervention (PPCI). Quantitative data were presented as mean ± standard deviation (SD) or median [interquartile range (IQR)] or number (%) and qualitative data were presented as frequencies. Bivariate analysis was performed to determine correlation between IL-6 and LVEF using Spearman’s Correlation test.
Analysis showed this study population had mean age 55.83 ± 10.26 years, was dominated by male (90%) and about 80% had smoking as a cardiovascular risk factor. All of our subjects received medication based on current STEMI guideline. Our study showed a correlation between serum level of IL-6 with LVEF (p-value 0.043, correlation coefficient -0.456).

Conclusion
Our analysis suggests that there is an inverse correlation between admission circulating IL-6 level with LVEF in STEMI patients.
OR17. Clinical characteristics and risk factors of reduced ejection fraction in coronary artery disease patients undergoing percutaneous coronary intervention at sanglah hospital denpasar, bali, indonesia in 2021: a cross-sectional hospital-based study
Authors: Upadhana P S , Jagannatha G N P , Dewi P I S L , Nolan J , Pamungkas K M N , Wijaya A R , Wirawan H 
Published: April 2022

Abstract

Aims
This study was conducted to determine the clinical characteristics and risk factors of reduced ejection fraction (EF) in coronary artery disease (CAD) patients undergoing percutaneous coronary intervention (PCI).

Methods and Results
Analytical observational study with a cross-sectional study design was conducted. All patients diagnosed with CAD and had a history of PCI at Sanglah Hospital from December 2020 – June 2021 were enrolled. Univariate analysis was performed to demonstrate the baseline characteristics of the patients. Chi-Square analysis was performed to determine the association between variables. Kruskal-Wallis analysis was performed to determine the differences in clinical characteristics between groups of patients based on the EF. There were 196 patients included in this study. Most of the patients were male (n = 135, 68.9%), with median age of 59 (22-81). The median of the EF was 59.2% (22-81). The most common comorbid found in the patients was hypertension (n = 108, 55.1%). Chi-Square analysis showed a significant association between hyperuricemia (p = 0.019; PR = 1.815; 95%CI= 1.163-2.831), arrhythmias (p = 0.002; PR = 2.271; 95%CI=1.491-3.459), and cardiomegaly (p = 0.011; PR = 1.722; 95%CI=1.151-2.577) with the reduced EF. In logistic regression analysis, arrhythmia (p = 0.009; PR = 4.191; 95%CI=1.426-12.320) was significantly associated with reduced EF. Kruskal-Wallis analysis showed a significant difference in white blood cell (p = 0.021), neutrophil (p = 0.027), and serum glutamic pyruvic transaminase (p = 0.013) in patients based on the EF.

Conclusion
The comorbidity of CAD had a significant association with the reduced EF. Early intervention against this factor can improve the quality of management in the patient.
OR29. Echocardiography Parameters Affecting Hospitalization in Pulmonary Arterial Hypertension Patients: A Single Center Study
Authors: Syafar R H , Yanni M , Syant B A , Khairat M , Widyastuti W , Sari R P , Ananza D A 
Published: April 2022

Abstract

Aims
Pulmonary arterial hypertension (PAH) is one form of pulmonary hypertension characterized by increased of mean pulmonary arterial pressure and pulmonary vascular resistance with normal pulmonary arterial wedge pressure. Echocardiography is one of modalities to assess PAH. The aim of this study is to describe hospitalization risk based on echocardiography parameters in patients with PAH in DR. M. Djamil Hospital.

Methods and Results
We enrolled patients with PAH who underwent echocardiography examination from January 2016 until July 2020. There were 47 patients met the inclusion criteria. Mean of age was 34±13 years old. About 68% patients were female and the most common symptom was dyspnea (92%). Congenital heart disease was the most common etiology in PAH (89%) and about 53% patients got vasodilator. Mean of systolic pulmonary artery (PA) pressure was 68±35 mmHg, tricuspid valve gradient was 60±35 mmHg, and tricuspid regurgitation velocity maximum was 3.7±1.1 m/s. Hospitalization within a year after first echocardiography is found in 21 patients (45%). By T-test analysis, we found a significant difference in mean PA pressure between hospitalized and non-hospitalized group (69 mmHg vs 24 mmHg, p = 0.000). There were no significant difference in another echocardiography parameter such as right atrial dimension, right ventricular dimension and function, estimating right atrial pressure, pericardial effusion, pulmonary acceleration time, and pulmonary artery diameter.

Conclusion
Higher mean PA pressure was a significant factor affecting hospitalization in PAH patients. Further study using invasive examination is needed to confirm the result.