bluuebunny/crossref_metadata_2025_split huggingface dataset:
Culturally fluent real-world disparities can blind us to bias: Experiments using a cultural lens can help
Authors: Oyserman Daphna , Jeon Amabel Youngbin 
Published: May 2022

AbstractCulture provides people with rich, detailed, implicit, and explicit knowledge about associations (what goes together) and contingencies (how situations are likely to unfold). These culture-based expectations allow people to get through their days without much systematic reasoning. Experimental designs that unpack these situated effects of culture on thinking, feeling, and doing can advance bias research and direct policy and intervention.
Understanding causal mechanisms in the study of group bias
Authors: Duell Dominik , Landa Dimitri 
Published: May 2022

AbstractCausal mechanisms' portability and their predictions in sometimes counterfactual settings point to the value of studies with details of interactions and/or convenience samples that depart from those in the proximate contexts of the phenomena of interest. The proper role of such contexts must be construed within an explanatory framework attentive to the nature and properties of relevant causal mechanisms.
The unbearable limitations of solo science: Team science as a path for more rigorous and relevant research
Authors: Ledgerwood Alison , Pickett Cynthia , Navarro Danielle , Remedios Jessica D. , Lewis Neil A. 
Published: May 2022

AbstractBoth early social psychologists and the modern, interdisciplinary scientific community have advocated for diverse team science. We echo this call and describe three common pitfalls of solo science illustrated by the target article. We discuss how a collaborative and inclusive approach to science can both help researchers avoid these pitfalls and pave the way for more rigorous and relevant research.
Cesario's framework for understanding group disparities is radically incomplete
Authors: Weaving Morgan , Fine Cordelia 
Published: May 2022

AbstractCesario argues that experimental studies of bias tell us little about why group disparities exist. We argue that Cesario's alternative approach implicitly frames understanding of group disparities as a false binary between “bias” and “group differences.” This, we suggest, will contribute little to our understanding of the complex dynamics that produce group disparities, and risks inappropriately rationalizing them.
Special issue on ontologies and standards for intelligent systems: editorial
Authors: Olszewska Joanna Isabelle , Bermejo-Alonso Julita , Sanz Ricardo 
Published: May 2022

Abstract
Day by day, new intelligent systems and autonomous machines are being developed to help and assist humans in a myriad of activities ranging from smart manufacturing to smart cities. Such new-generation intelligent systems need to work in teams and communicate with humans and other agents/robots to share information and coordinate activities. Furthermore, there is an increasing demand from government agencies and the private sector alike to use Unmanned Aerial Vehicles (UAVs), Unmanned Ground Vehicles (UGVs), Unmanned Surface Vehicles (USVs), and Autonomous Underwater Vehicles (AUVs) for tasks including search and rescue, surveillance, and monitoring. As these intelligent systems have to interact with humans in several scenarios involving multi-agent collaboration, data collection, and decision-making, it is urgent to discuss the technical as well as the ethical aspects in their design and function. Hence, ontology-based models for this Robotics and Automation (R&A) domain have the potential to enable a clear communication among the different intelligent systems and stakeholders, the formulations of standards, and the building of AI-based and robotics systems with full alignment with what stakeholders expect from these intelligent systems, in terms of economical benefits and enhanced human well-being.
Dealing with the populist radical right in parliament: mainstream party responses toward the Alternative for Germany
Authors: Heinze Anna-Sophie 
Published: May 2022

AbstractIn recent years, populist radical right parties (PRRPs) have continued to establish themselves in parliaments across Europe. However, there is little research on party responses in parliaments. This article explores how mainstream parties have dealt with the Alternative for Germany (AfD) in state parliaments. Its contribution is twofold: theoretically, it links the existing literature on party responses to the parliamentary arena and proposes a comprehensive framework for analyzing party responses in parliament, distinguishing between the formal and the policy level. Moreover, it tries to understand the variation of responses by emphasizing three important factors: party ideology, the government–opposition divide, and the federal structure of parties. Empirically, the article explores the crucial variation of response patterns toward the AfD at the subnational level, which is often neglected in the study of PRRPs. The results show that party responses reflect an ongoing learning process with no ‘magic formula’ in sight. Overall, the article underlines the importance of party responses in the initial phase for the PRRPs’ impact and offers substantial theoretical and empirical impetus for future research.
An Integration of Numerical Modeling and Paleoenvironmental Analysis Reveals the Effects of Embankment Construction on Long‐Term Salt Marsh Accretion
Authors: Pannozzo N. , Smedley Rachel K. , Chiverrell Richard C. , Carnacina Iacopo , Leonardi Nicoletta 
Published: May 2022

AbstractThere are still numerous uncertainties over the influence of anthropogenic interventions on salt marsh dynamics. This study uses the Ribble Estuary as a test case and an integrated approach of numerical modeling and paleoenvironmental analysis to investigate the contribution of embankment construction to long‐term marsh accretion. Accretion rates derived using optically stimulated luminescence dating (OSL) were combined with a multi‐proxy paleoenvironmental investigation on sediment cores extracted from the salt marsh, the mobile seafloor of the central Irish Sea and the river catchment area. These analyses provided a first evolutionary perspective on the Ribble Estuary preceding any management interventions. The paleoenvironmental analyses were then compared to simulations conducted using the hydrodynamic model Delft3D to investigate the effects of embankment construction on estuarine hydrodynamics and morphodynamics of the salt marsh over the period constrained by the OSL. The numerical simulations showed that embankments were responsible for an overall intensification of the ebb currents in the system which promoted sediment export. The paleoenvironmental analyses showed that the marsh has been accreting at a rate of 4.61 to 0.86 cm yr−1 over the last ca. 190 years and that the high sedimentation rate was caused by a naturally high rate of sediment supply. The model‐data integration showed that the effects of the embankment construction on sediment transport did not compromise the long‐term resilience of the salt marsh because of the high rates of sediment supply and the river dredging which enhanced the flood dominance of the tide near the tidal flat.
Coherency of Lightning Sferics
Authors: Bai X. , Füllekrug M. 
Published: May 2022

AbstractThe amplitudes of lightning sferics are commonly used for data analyses, for example, in lightning location networks. This contribution investigates the coherency of lightning sferics, which is calculated from the phase of the analytic complex signal. The complex signal is obtained from the Hilbert transform with the recorded signal as the input signal. This analytic signal is composed of amplitudes with corresponding phases. Rigorous selection criteria are applied to ensure that consistent events are used to calculate distance‐dependent average sferics waveforms which are summarized in waveform banks for the amplitude and coherency. The impulse response to lightning flashes is derived from an averaged waveform which is used to detect individual lightning events. It is shown that the coherency waveform bank is in general agreement with the amplitude waveform bank, that is, the relative arrival times of the ground and sky waves. The coherency waveform bank exhibits the same number of skywaves on the logarithmic scale, but a less attenuated ground wave when compared to the amplitude waveform bank. The results of this study show that the phase of sferics offers additional information to amplitudes, which could potentially be used for the interferometric lightning location with long‐range lightning detection networks.
Energetic Charged Particle Fluxes Relevant to Ganymede's Polar Region
Authors: Paranicas C. , Mauk B. H. , Kollmann P. , Clark G. , Haggerty D. K. , Westlake J. , Liuzzo L. , Masters A. , Cassidy T. A. , Bagenal F. , Bolton S. 
Published: May 2022

AbstractThe JEDI instrument made measurements of energetic charged particles near Ganymede during a close encounter with that moon. Here we find ion flux levels are similar close to Ganymede itself but outside its magnetosphere and on near wake and open field lines. But energetic electron flux levels are more than a factor of 2 lower on polar and near‐wake field lines than on nearby Jovian field lines at all energies reported here. Flux levels are relevant to the weathering of the surface, particularly processes that affect the distribution of ice, since surface brightness has been linked to the open‐closed field line boundary. For this reason, we estimate the sputtering rates expected in the polar regions due to energetic heavy ions. Other rates, such as those related to radiolysis by plasma and particles that can reach the surface, need to be added to complete the picture of charged particle weathering.
Unidentified major p-type source in SnSe: Multivacancies
Authors: Nguyen Van Quang , Trinh Thi Ly , Chang Cheng , Zhao Li-Dong , Nguyen Thi Huong , Duong Van Thiet , Duong Anh Tuan , Park Jong Ho , Park Sudong , Kim Jungdae , Cho Sunglae 
Published: May 2022

AbstractTin selenide (SnSe) is considered a robust candidate for thermoelectric applications due to its very high thermoelectric figure of merit, ZT, with values of 2.6 in p-type and 2.8 in n-type single crystals. Sn has been replaced with various lower group dopants to achieve successful p-type doping in SnSe with high ZT values. A known, facile, and powerful alternative way to introduce a hole carrier is to use a natural single Sn vacancy, VSn. Through transport and scanning tunneling microscopy studies, we discovered that VSn are dominant in high-quality (slow cooling rate) SnSe single crystals, while multiple vacancies, Vmulti, are dominant in low-quality (high cooling rate) single crystals. Surprisingly, both VSn and Vmulti help to increase the power factors of SnSe, whereas samples with dominant VSn have superior thermoelectric properties in SnSe single crystals. Additionally, the observation that Vmulti are good p-type sources observed in relatively low-quality single crystals is useful in thermoelectric applications because polycrystalline SnSe can be used due to its mechanical strength; this substance is usually fabricated at very high cooling speeds.
Heat transfer control using a thermal analogue of coherent perfect absorption
Authors: Li Ying , Qi Minghong , Li Jiaxin , Cao Pei-Chao , Wang Dong , Zhu Xue-Feng , Qiu Cheng-Wei , Chen Hongsheng 
Published: May 2022

AbstractRecent investigations on non-Hermitian physics have unlocked new possibilities to manipulate wave scattering on lossy materials. Coherent perfect absorption is such an effect that enables all-light control by incorporating a suitable amount of loss. On the other hand, controlling heat transfer with heat may empower a distinct paradigm other than using thermal metamaterials. However, since heat neither propagates nor carries any momentum, almost all concepts in wave scattering are ill-defined for steady-state heat diffusion, making it formidable to understand or utilize any coherent effect. Here, we establish a scattering theory for heat diffusion by introducing an imitated momentum for thermal fields. The thermal analogue of coherent perfect absorption is thus predicted and demonstrated as the perfect absorption of exergy fluxes and undisturbed temperature fields. Unlike its photonic counterpart, thermal coherent perfect absorption can be realized for regular thermal materials, and be generalized for various objects.
Quadrivalent mosaic HexaPro-bearing nanoparticle vaccine protects against infection of SARS-CoV-2 variants
Authors: Kang Yin-Feng , Sun Cong , Sun Jing , Xie Chu , Zhuang Zhen , Xu Hui-Qin , Liu Zheng , Liu Yi-Hao , Peng Sui , Yuan Run-Yu , Zhao Jin-Cun , Zeng Mu-Sheng 
Published: May 2022

AbstractEmerging SARS-CoV-2 variants of concern (VOCs) harboring multiple mutations in the spike protein raise concerns on effectiveness of current vaccines that rely on the ancestral spike protein. Here, we design a quadrivalent mosaic nanoparticle vaccine displaying spike proteins from the SARS-CoV-2 prototype and 3 different VOCs. The mosaic nanoparticle elicits equivalent or superior neutralizing antibodies against variant strains in mice and non-human primates with only small reduction in neutralization titers against the ancestral strain. Notably, it provides protection against infection with prototype and B.1.351 strains in mice. These results provide a proof of principle for the development of multivalent vaccines against pandemic and potential pre-emergent SARS-CoV-2 variants.
Unraveling the electronegativity-dominated intermediate adsorption on high-entropy alloy electrocatalysts
Authors: Hao Jiace , Zhuang Zechao , Cao Kecheng , Gao Guohua , Wang Chan , Lai Feili , Lu Shuanglong , Ma Piming , Dong Weifu , Liu Tianxi , Du Mingliang , Zhu Han 
Published: May 2022

AbstractHigh-entropy alloys have received considerable attention in the field of catalysis due to their exceptional properties. However, few studies hitherto focus on the origin of their outstanding performance and the accurate identification of active centers. Herein, we report a conceptual and experimental approach to overcome the limitations of single-element catalysts by designing a FeCoNiXRu (X: Cu, Cr, and Mn) High-entropy alloys system with various active sites that have different adsorption capacities for multiple intermediates. The electronegativity differences between mixed elements in HEA induce significant charge redistribution and create highly active Co and Ru sites with optimized energy barriers for simultaneously stabilizing OH* and H* intermediates, which greatly enhances the efficiency of water dissociation in alkaline conditions. This work provides an in-depth understanding of the interactions between specific active sites and intermediates, which opens up a fascinating direction for breaking scaling relation issues for multistep reactions.
Structural identification of vasodilator binding sites on the SUR2 subunit
Authors: Ding Dian , Wu Jing-Xiang , Duan Xinli , Ma Songling , Lai Lipeng , Chen Lei 
Published: May 2022

AbstractATP-sensitive potassium channels (KATP), composed of Kir6 and SUR subunits, convert the metabolic status of the cell into electrical signals. Pharmacological activation of SUR2- containing KATP channels by class of small molecule drugs known as KATP openers leads to hyperpolarization of excitable cells and to vasodilation. Thus, KATP openers could be used to treat cardiovascular diseases. However, where these vasodilators bind to KATP and how they activate the channel remains elusive. Here, we present cryo-EM structures of SUR2A and SUR2B subunits in complex with Mg-nucleotides and P1075 or levcromakalim, two chemically distinct KATP openers that are specific to SUR2. Both P1075 and levcromakalim bind to a common site in the transmembrane domain (TMD) of the SUR2 subunit, which is between TMD1 and TMD2 and is embraced by TM10, TM11, TM12, TM14, and TM17. These KATP openers synergize with Mg-nucleotides to stabilize SUR2 in the NBD-dimerized occluded state to activate the channel.
Mechanical instability generated by Myosin 19 contributes to mitochondria cristae architecture and OXPHOS
Authors: Shi Peng , Ren Xiaoyu , Meng Jie , Kang Chenlu , Wu Yihe , Rong Yingxue , Zhao Shujuan , Jiang Zhaodi , Liang Ling , He Wanzhong , Yin Yuxin , Li Xiangdong , Liu Yong , Huang Xiaoshuai , Sun Yujie , Li Bo , Wu Congying 
Published: May 2022

AbstractThe folded mitochondria inner membrane-cristae is the structural foundation for oxidative phosphorylation (OXPHOS) and energy production. By mechanically simulating mitochondria morphogenesis, we speculate that efficient sculpting of the cristae is organelle non-autonomous. It has long been inferred that folding requires buckling in living systems. However, the tethering force for cristae formation and regulation has not been identified. Combining electron tomography, proteomics strategies, super resolution live cell imaging and mathematical modeling, we reveal that the mitochondria localized actin motor-myosin 19 (Myo19) is critical for maintaining cristae structure, by associating with the SAM-MICOS super complex. We discover that depletion of Myo19 or disruption of its motor activity leads to altered mitochondria membrane potential and decreased OXPHOS. We propose that Myo19 may act as a mechanical tether for effective ridging of the mitochondria cristae, thus sustaining the energy homeostasis essential for various cellular functions.
Experimental research on surface acoustic wave microfluidic atomization for drug delivery
Authors: Huang Qing-Yun , Le Ying , Hu Hong , Wan Zhi-jian , Ning Jia , Han Jun-Long 
Published: May 2022

AbstractThis paper demonstrates that surface acoustic wave (SAW) atomization can produce suitable aerosol concentration and size distribution for efficient inhaled lung drug delivery and is a potential atomization device for asthma treatment. Using the SAW device, we present comprehensive experimental results exploring the complexity of the acoustic atomization process and the influence of input power, device frequency, and liquid flow rate on aerosol size distribution. It is hoped that these studies will explain the mechanism of SAW atomization aerosol generation and how they can be controlled. The insights from the high-speed flow visualization studies reveal that it is possible by setting the input power above 4.17 W, thus allowing atomization to occur from a relatively thin film, forming dense, monodisperse aerosols. Moreover, we found that the aerosol droplet size can be effectively changed by adjusting the input power and liquid flow rate to change the film conditions. In this work, we proposed a method to realize drug atomization by a microfluidic channel. A SU-8 flow channel was prepared on the surface of a piezoelectric substrate by photolithography technology. Combined with the silicon dioxide coating process and PDMS process closed microfluidic channel was prepared, and continuous drug atomization was provided to improve the deposition efficiency of drug atomization by microfluidic.
SARS-CoV-2 RNA and antibody dynamics in a Dutch household study with dense sampling frame
Authors: Han Wanda G. H. , Swart Arno , Bonačić Marinović. Axel , Eggink Dirk , Reimerink Johan , Wijsman Lisa A. , van der Veer Bas , van den Brink Sharon , van den Brandt Anne-Marie , van Tol Sophie , Godeke Gert-Jan , Brouwer Fion , Hoogerwerf Marieke ,   The Dutch F. F. X.-COVID-19 Research Group, van Gageldonk-Lafeber Arianne B. , van der Hoek Wim , van den Hof Susan , Meijer Adam , Reukers Daphne F. M. , Reusken Chantal , Roof Inge , Rots Nynke , Reukers Daphne F. M. , Rots Nynke , Reusken Chantal , Meijer Adam 
Published: May 2022

AbstractThis study investigated the dynamics of SARS-CoV-2 infection and diagnostics in 242 household members of different ages and with different symptom severity after SARS-CoV-2 exposure early in the pandemic (March–April 2020). Households with a SARS-CoV-2 confirmed positive case and at least one child in the Netherlands were followed for 6 weeks. Naso (NP)- and oropharyngeal (OP) swabs, oral fluid and feces specimens were analyzed for SARS-CoV-2 RNA and serum for SARS-CoV-2-specific antibodies. The dynamics of the presence of viral RNA and the serological response was modeled to determine the sampling time-frame and sample type with the highest sensitivity to confirm or reject a SARS-CoV-2 diagnosis. In children higher viral loads compared to adults were detected at symptom onset. Early in infection, higher viral loads were detected in NP and OP specimens, while RNA in especially feces were longer detectable. SARS-CoV-2-specific antibodies have 90% probability of detection from 7 days (total Ig) and 18 days (IgG) since symptom onset. For highest probability of detection in SARS-CoV-2 diagnostics early in infection, RT-PCR on NP and OP specimens are more sensitive than on oral fluid and feces. For SARS-CoV-2 diagnostics late after infection, RT-PCR on feces specimens and serology are more valuable.
Direct RNA targeted in situ sequencing for transcriptomic profiling in tissue
Authors: Lee Hower , Marco Salas Sergio , Gyllborg Daniel , Nilsson Mats 
Published: May 2022

AbstractHighly multiplexed spatial mapping of transcripts within tissues allows for investigation of the transcriptomic and cellular diversity of mammalian organs previously unseen. Here we explore a direct RNA (dRNA) detection approach incorporating the use of padlock probes and rolling circle amplification in combination with hybridization-based in situ sequencing chemistry. We benchmark a High Sensitivity Library Preparation Kit from CARTANA that circumvents the reverse transcription needed for cDNA-based in situ sequencing (ISS) via direct RNA detection. We found a fivefold increase in transcript detection efficiency when compared to cDNA-based ISS and also validated its multiplexing capability by targeting a curated panel of 50 genes from previous publications on mouse brain sections, leading to additional data interpretation such as de novo cell clustering. With this increased efficiency, we also found to maintain specificity, multiplexing capabilities and ease of implementation. Overall, the dRNA chemistry shows significant improvements in target detection efficiency, closing the gap to other fluorescent in situ hybridization-based technologies and opens up possibilities to explore new biological questions previously not possible with cDNA-based ISS.
An efficient ANFIS-EEBAT approach to estimate effort of Scrum projects
Authors: Arora Mohit , Verma Sahil , Kavita  , Wozniak Marcin , Shafi Jana , Ijaz Muhammad Fazal 
Published: May 2022

AbstractSoftware effort estimation is a significant part of software development and project management. The accuracy of effort estimation and scheduling results determines whether a project succeeds or fails. Many studies have focused on improving the accuracy of predicted results, yet accurate estimation of effort has proven to be a challenging task for researchers and practitioners, particularly when it comes to projects that use agile approaches. This work investigates the application of the adaptive neuro-fuzzy inference system (ANFIS) along with the novel Energy-Efficient BAT (EEBAT) technique for effort prediction in the Scrum environment. The proposed ANFIS-EEBAT approach is evaluated using real agile datasets. It provides the best results in all the evaluation criteria used. The proposed approach is also statistically validated using nonparametric tests, and it is found that ANFIS-EEBAT worked best as compared to various state-of-the-art meta-heuristic and machine learning (ML) algorithms such as fireworks, ant lion optimizer (ALO), bat, particle swarm optimization (PSO), and genetic algorithm (GA).