bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Proton Pump Inhibitor Based Triple Therapy with Apple Cider Vinegar on Helicobacter Pylori Eradication
Authors: Shahbazi Shaahin , Vahdat Shariatpanahi Zahra , Sadeghifard Nourkhoda 
Published: January 2022

Background: The purpose of this study was to evaluate the effect of apple cider vinegar plus PPI-based triple therapy on eradication of Helicobacter Pylori (H.pylori) infection.
Materials and Methods: 116 patients with H. pylori infection were included in this randomized clinical trial. Patients in control group (n=59) received amoxicillin, clarithromycin, and pantaprazole twice daily. Patients in study group (57 patients) received the same regimen plus 30 mL of apple cider vinegar twice daily. The duration of therapy for study and control were 10 and 14 days respectively. Four weeks after the completion of therapy, Urea breath test was performed to assess the success of H.pylori infection eradication.
Results: 86% of patients in control group in comparison to 88% in apple cider vinegar group responded to eradication therapy (P=0.41).
Conclusion: Addition of apple cider vinegar to proton pomp inhibitor (PPI)-based triple therapy may decrease the duration of H. pylori treatment but it was not statistically significant. Thus, our results showed no efficacy of apple cider vinegar in H. pylory eradication treatment.
Effects of Laparoscopic Roux-en-Y Gastric Bypass on Anthropometric Characteristics, Hypertension, Type 2 Diabetes Mellitus and Metabolic Syndrome: An Iranian Experience
Authors: Zamani Mohammad Mahdi , Ghoghaei Morteza , Khajeh Elias , Taghdiri Foad , Taghdiri Soudeh , Sedaghat Mojtaba , Toolabi Karamollah 
Published: January 2022

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Background: Surgically induced weight loss is a treatment option for the management of obesity and the related common disorders. This study evaluated the beneficial effects of bariatric surgery on metabolic profile and the prevalence of metabolic syndrome (MetS) among Iranian patients.
Materials and Methods: A prospective observational study was performed on 26 morbidly obese patients scheduled for bariatric surgery, using laparoscopic Roux-en-Y gastric bypass (LRYGB). The parameters of hypertension, type 2 diabetes mellitus (T2DM), hyperlipidemia, MetS prevalence, and anthropometric measurements of Iranian patients, were recorded, at the preoperative visit and in follow-ups. The follow-up was performed for a median of 12 months, and the change in MetS prevalence and its componnts were assesed.
Results: LRYGB induced a mean weight loss of 69.0Â±21.2%, after 12 months. Preoperative MetS was diagnosed in 21 patients (84%) and decreased to 6 patients (24%) after LRYGB (P=0.001). Likewise, the prevalence of hypertension was significantly decreased from 76% (pre-LRYGB values) to 20% (post-LRYGB values) (P=0.001). The prevalence of T2DM was also decreased from 20% to 8% (P=0.5).
Conclusion: According to our results,Â RYGB produced a rapid and significant weight loss and improvement in hypertension and MetS within one year but there was a controversy about the improvement of T2DM, in Iranian morbidly obese patients.
Evaluating Maternal Social Support in Low Birth Weight Neonates Comparing With Normal Neonates in 2012
Authors: Kazemi Reza , Riahinejad Soheila , Farhangfar Behrouz , Arabi Marzieh 
Published: January 2022

Introduction: Pregnancy as a stressful event may cause some consequence for both mother and infant such as low birth weight (LBW). LBW is seen in about 7% of pregnancies in Iran. It was proved there is a correlation between infants weight and maternal social support. This study was designed to evaluate maternal perceived social support in LBW infants and infants with normal weight.
Methods and Materials: This was a case-Control study which was done in Isfahan, Iran during April-November 2012 on 188 participants in 2 groups. In case group we had evaluated mothers with low birth weight infants and control group were mother with normal infants. Farsi version of Multidimensional Scale of Perceived Social Support (MSPSS-P) was used for social support evaluation.
Results: In LBW group mean family support subscale score was 14.87 Â± 4.33, Mean friends support subscale score was 9.65 Â± 5.89 and significant others support subscale mean score was 15.18 Â± 5.11. In normal weightÂ group mean family support subscale score was 18.46 Â± 3.98, Mean friends support subscale score was 15.4 Â± 6.41 and significant others support subscale mean score was 18.46 Â± 4.1.
Conclusion: Maternal perceived prenatal social support could be a predictor for Â infants birth weight. Supportive family could helps pregnant women to reduce adverse pregnancy out comes such as low birth weight.
Prevalence of Late-Onset Multiple Sclerosis in Fars Province, Southern Iran
Authors: Sharifian Maryam , Izadi Sadegh , Nikseresht Alireza , Rafiee Shima 
Published: January 2022

Background: Multiple Sclerosis (MS) is the most common demyelinating and inflammatory disease of the central nevus system especially in young adults, but in a subgroup of patients the first clinical symptoms present after the age of 50. This clinical presentation is defined as Late-Onset Multiple Sclerosis (LOMS). The incidence and prevalence of MS including LOMS vary geographically. The aim of this study is to determine epidemiological characteristics of LOMS in Fars province, South of Iran.Materials andÂ Methods: All patients aged over 50, known to have had definite MS according to MC Donaldâ€™s criteria, being members of Shiraz University Multiple Sclerosis Database (SUMSD), were evaluated in this study. The following data were recorded via a questionnaire indicating gender, age at the time of diagnosis, clinical course and details of disease- modifying therapies (Beta-Interferon).Results: Among a total of 1705 patients, 7.2% were identified as having LOMS and 3.1% identified as having very late-onset MS (VLOMS). Mean age of the patients with LOMS at the time of diagnosis was 58.81 Â± 2.6 yearsÂ (20.8% were male and 107 (79.2%) were female). 8.9 % had EDSS 6 and more. 89.1% of patients received Beta-Interferon as a disease-modifying treatment including Avonex (16.3 %), Cinovex (32.6%), Rebif (14.1%) and Betaferon (26.1 %). Conclusion: In our study, 7.2% of all MS patients were identified as LOMS. In LOMS subgroup, clinical history and para-clinical data should be thoroughly evaluated to exclude more common conditions like cerebrovascular disease. [GMJ. 2014;3(4):228-31]
Frequency of Suicide Ideation and Attempt in HIV infected patients referred to behavioral health counseling center of Rafsanjan (RUMS) and Kerman University of medical sciences (KUMS) in 2012
Authors: Bidaki Reza , Soltani Hossein , Zolala Hossein , Sayadi Anari Ahmadreza , Asadi Razie , Shafee Ali , Riahy Ali , Asadpour Mohammad , Salehi  Shahrbabaki Mohammad  Hossein , Sabouri Ghannad Masoud , Khajekarimaddini Zahiraddin 
Published: January 2022

Background: Suicidal behavior and HIV/AIDS are considered as significant public health concerns. HIV infection has been associated with elevated risk of suicidal ideation.
Methods and Materials: Cross-sectional and descriptive research design was used to record socio-demographic data of the study. The suicidal ideation scale BECK was used to determine and measure the frequency of suicide ideation and attempt in HIV infected (HIV+) persons referred to behavioral health counseling center of Rafsanjan University of medical sciences (RUMS) and Kerman University of medical sciences (KUMS) in 2012.
Results: Â Â Men had more suicidal ideation than women after the diagnosis of infection with HIV. More cases of Â HIV positive persons Â with durationÂ of Â lessÂ than 10Â andÂ moreÂ Â thanÂ Â 14 years, andÂ most cases of lessÂ than 40 years-oldÂ had suicidal ideation. There was no significant difference between suicidal ideation in HIV-infected individuals and factors such as gender, age, and duration of HIV-infection (p >0.05).
Conclusion: Suicidal ideation and attempt is common in HIV infected patients which needs more assessment and prevention.
Transient Yellow Finger Nails Discoloration: Two Different Causes
Authors: Brzezinski Piotr , Chiriac Anca , Chiriac Anca E 
Published: January 2022

Background: Nail disorders comprise approximately 10% of all dermatological conditions. Abnormalities in the color of nails are called ungal dyschromia or chromonychia. Ungual dyschromia may be endogenous or exogenous. Yellow discoloration of the nails has been reported during the last years as separate observation related to drug administration, during hemodialysis and associated with pulmonary diseases as yellow nail syndrome.
Case reports:Â A 23-year-old female patient was diagnosed with yellow nails induced by application of a specific nail polish. A 67-year-old man presented with transient nail discoloration as a result of the exacerbation of his chronic pulmonary disease.
Conclusion:Â Our cases illustrate transient yellow discoloration of finger nails associated with the use of nail polish, and with an acute episode of chronic bronchitis, with full recovery in the absence of any treatment.
Stroke subtypes in southern Iran
Authors: Safari Rasool , Borhanihaghighi Afshin , Heydari Seyed Taghi , Safari Anahid , Cruz-Flores Salvador 
Published: January 2022

Objective: To investigate about frequency of different subtypes of stroke in south of Iran
Methods: ThisÂ is a retrospective, single-center studyÂ conducted at Namazi Hospital, Shiraz, south of Iran. Age, sex, length of hospitalization and Â mortalityÂ ofÂ stroke patients were recorded by reviewing hospital medical records.
Results: 16Â 351 patients (53.6% male, 46.4%female) were recruited. Â Ischemic stroke (10750 patients, 65.7%), intracerebral hemorrhage(3282 patients,20.1%) and subarachnoid hemorrhage(1057 patients,6.5%) Â were the most common subtypes of stroke, respectively. In 1262 patients (7.7%) the stroke subtype could not been specified. Ischemic stroke and intracerebral hemorrhage were more common in men but subarachnoid hemorrhage was more common in women. Subarachnoid hemorrhage occurred significantly in younger patients. Mortality was significantly higher in intracerebral hemorrhage. Hospital stay was significantly longer in subarachnoid hemorrhage group.
Conclusion: the distribution of the differentÂ subtypes of stroke in Iran is similar to Caucasians.
Analysis of Hyperthermia Effect on Peripheral Blood Natural Killer Cell Cytotoxicity against SW-872 Cell Line
Authors: Atashzar Mohammad Reza , Jalili Sajad 
Published: January 2022

Background: Natural killer (NK) cells are a type of cytotoxic lymphocyte. It is revealed that hyperthermia which is used in cancer treatment, increases natural killer cell activity. In this study, our aim was to analyze effects of in-vitro hyperthermia on human Natural Killer cytotoxicity against SW-872 cell line. Materials and Methods: In this study, we used SW-872 liposarcoma cell line as a target cell. Peripheral blood NK cells were isolated from normal individuals by MACS. NK cells were treated at 39Â°C for 1hr .The expression of CD69 on the surface of NK cells was examined by flow cytometry at different time points including 0, 6 and 12 hrs. NK cell cytotoxicity was measured by LDH assay 12hrs after co-culture with SW-872. The results were compared to the conditions that both NK cells and SW-872 cells were heat treated at 39Â°C for 12hrs. Results: Our results revealed that cell killing activity of NK cells treated with heating alone was increased 6hrs after heat treatment at 39Â°C compared with heat-treated NK-target cells co-culture. While in heat-treated NK-target cells co-culture the maximum cytotoxicity was observed 12hrs after heat treatment at 39Â°C. Conclusion: These results showed that thermotherapy could be a feasible method to stimulate immune response against tumor cells. [GMJ. Â 2015;4(3):75-81]
The Effectiveness of Group-Therapy Intervention on Quality of Life and Hope of Women Infected with Human immunodeficiency virus
Authors: Mohammadpour DoughAbadi Niloufar , Soleimani Aliakbar , Ahmadi Khodabakhsh , Javidi Nasirudin 
Published: January 2022

Background: AIDS is one of the most important causes of death in the world and the affected patients, in addition to physical problems, experience various psychological problems, especially symptoms of depression such as hopelessness, isolation and social isolation. Therefore, the aim of this study was to determine the effectiveness of group-therapy intervention to improve quality of life and hope in women with HIV.
Materials and Methods: In this quasi-experimental study, pretest and post-test design with a control group was used. The sample size included 24 HIV-positive patients referring to Health Care Center of Mashhad city in 2014 that were randomly divided into 12 patients in the case group and 12 in the control group. For data analysis, multivariate analysis of covariance was used.
Results: The results showed that hope therapy interventions improved the quality of life of patients with HIV in two dimensions (cognitive and social). The interventions led to a significant increase in both navigational and operating dimensions of hope in the experimental group, compared with the control group.
Conclusion: Therefore, interventions with the protocol of hope therapy can improve quality of life and hope in patients with certain diseases. Regarding the efficacy of the intervention of hope therapy, it is suggested that this method be used as a procedure in AIDS counselling.
Keywords: Group Therapy, Quality Of Life, Hope, AIDS
Immunology of stroke
Authors: Safari Anahid , Safari Rasool , Borhani-Haghighi Afshin 
Published: January 2022

Stroke, a multifactorial disease, has distinct pathophysiologic mechanisms, among which inflammation plays a pivotal role. Various types of inflammatory cells, substances, and molecules emerge in the ischemic stroke. Neutrophils, Tcell subtypes, macrophages, microglial cells, dendritic cell, mast cells, asrocytes, as influential cell, tumor necrosis factor_α, interleukin-17, interleukin-10, as released substances, and vascular cell adhesion molecule-1 (VCAM-1), leukocyte very late antigen-4 (VLA-4), and glial fibrillary acidic protein (GFAP), as cellular adhesion molecules. Lymphocytes' invasion to the ischemic brain tissue occurs as the result of VLA-4 ̶ VCAM-1 interaction. Regarding Tcell subtypes, CD4+ cells have known detrimental effects in the ischemic area, while natural killer T cells (NKT cells) and γδ T cells have minor importance in the early stage of ischemia. While some studies proved the cerebroprotective impact of T regulatory cells, others refuted this by presenting a prominent harmful role of them. Bcells have important protective function by releasing IL-10. Neutrophils along with microglial cell, appearing as the first inflammatory cell in the ischemic tissue, and also macrophages deteriorate ischemia. Mast cells and dendritic cells are of great value in stroke progression. The resting astrocytes are neuroprotective, whereas the activated ones present detrimental function in the ischemic region by expression of GFAP. Hence, stroke consequences occur as the result of systemic inflammatory response. The more activation of this system, the poorer neurological outcomes would be observed. As expected, anti-inflammatory interventions in the experimental stroke in animals, have revealed successful results as less infarct size and attenuated neurological damages.
The Effect of Oral Administration of Hypericum Perforatum on Serum Glucose and Lipids, Hepatic Enzymes and Lipid Peroxidation in Streptozotocin-Induced Diabetic Rats
Authors: Ghosian Moghadam MohammadHassan , Ansari Iman , Roghani Mehrdad , Ghanem Ali , Mehdizade Neda 
Published: January 2022

Background: In this research, the beneficial effects of oral administration of Hypericum perfoÂ­ratum (HP) on serum glucose and lipids, hepatic enzymes and the amount of malondialdehyde in Streptozotocin-induced diabetic rats are studied. Materials and Methods: In this experiÂ­mental study, 32 male rats where randomly divided into 4 groups of control, treatment-control, diabetic and treatment-diabetic. HP was orally administered to treatment groups over a period of 6 weeks. Serum glucose levels, triglyceride, total cholesterol along with HDL and LDL were all evaluated prior to initiation of the treatment, and at 3rd and 6th (last) week of treatment initiation, and in the end of the treatment, malondialdehyde and aminotransferase enzymes of the liver were evaluated. Results: regarding serum glucose levels and body weight measured in the 3rd and 6th week, the treatment-diabetic group didnâ€™t show a significant change compared to the diabetic group, regarding serum total cholesterol and LDL levels, a significant decrease was observed and regarding serum HDL, a significant increase was documented. Furthermore, treating the treatment-diabetic group with HP did not result in any significant decrease in serum triglyceride, malondialdehyde or alanine aminotransferase but, in fact, did cause a significant decrease in aspartate aminotransferase. Conclusions: Oral administration of HP did in fact have a beneficial effect on lowering serum levels of total cholesterol, LDL and the hepatic enzyme asÂ­partate aminotransferase and on raising the levels of HDL in diabetized rats with Streptozotocin. [GMJ.2017;6(4):319-29] DOI: 10.22086/gmj.v6i4.889
Effects of Apigenin and Apigenin- Loaded Nanogel on Induction of Apoptosis in Human Chronic Myeloid Leukemia Cells
Authors: Hashemi Mehrdad , Samadian Nooshin 
Published: January 2022

Background: Diet plays an important role in cancer prevention. Apigenin, a flavonoid with thechemical formula C15H10O5, is abundantly present in vegetables. Vegetarian foods containing flavonoids are rich sources of bioactive compounds. Flavonoids have been utilized in herbal treatment. Nanogels are drug delivery systems based on polymers and are used in tissue engineering and for drug delivery. This study was conducted to compare the effects of apigenin and a nanodrug on the viability of the K562 cell line of chronic myeloid leukemia at different durations under laboratory conditions. Materials and Methods: Chitosan was first dissolved in 1% acetic acid, and ethylene dichloride EDC and NHS were added to the solution. Then, the nanodrug was prepared by loading apigenin into stearate–chitosan nanogel (scs nanogel), and its physical and morphological characteristics were evaluated by TEM, DLS, and FTIR. Trypan blue staining, MTT assay, and flow cytometry were used to analyze the effects of various concentrations of apigenin and apigenin-loaded chitosan–stearate nanogel (APG–SCS) at 24, 48, and 72 h after they were applied to the K562 cell line. Results: The diameter of the nanodrug particles was measured using DLS and confirmed by TEM. The K562 cells treated with APG–SCS and with apigenin exhibited significant differences compared with the control (P < 0.05). Apoptosis was detected by flow cytometry. Conclusion: This study showed that the toxic effects of apigenin and the nanodrug improved with increasing concentrations and exposure durations compared to those in the control.The toxic effect of apigenin loaded into the stearate-chitosan nanogel was greater than apigenin, and the toxic effects of both materials were greater compared to the control under laboratory conditions.[GMJ.2018;7:e1008]
LITERATURA, CINEMA E DIFERENTES MATERIALIDADES:
Authors: Dos Santos Flaviane Fagundes , Dos Santos Glória Lima , Fernandes Fernanda Surubi 
Published: January 2022

O artigo objetiva analisar, a partir do estudo da Análise de Discurso, o papel da mulher no século XIX e o discurso de amor na obra Orgulho e preconceito, tomando como recorte o discurso de amor presente na obra literária e na cinematográfica, abordando a relação entre cinema e literatura. Nesse sentido, essa comparação ocorre na apresentação das diferentes adaptações e da análise da declaração de Sr. Darcy a Sra. Elizabeth Bennet regida por um discurso moralista e patriarcal, que condiciona e determina o lugar da mulher na sociedade impondo-lhe regras e limitações através de um discurso patriarcal, conservador e varonil, para isso, este estudo se fundamenta em teóricos como Foucault (1999), Orlandi (1990), Perrot (2007), Milanez e Bittencourt (2012), entres outros.
PATTERN OF SPACE DAN PERILAKU BERMAIN ANAK SEKOLAH SELAMA PENDIDIKAN JARAK JAUH (PJJ)
Authors: Cardiah Tita , Sudarisman Irwan , Natasya Egha Fauzia , Putri Amelya Rahmadani , Senawianto Alif Nurrahiim , Andiyan Andiyan 
Published: January 2022

Abstract: Learning activities for school children during the Covid-19 pandemic were carried out using the Distance Learning method. Distance learning indirectly changes children's behavior both while studying and playing. The restriction of activities and play space for school children during Distance Learning method is a change that all children must face, including children living in housing. Pattern of Space and environmental settings, especially the residential environment, have a major influence on children's playing behavior. This study uses a qualitative descriptive method, which is to analyze through comparison of survey data and direct observation from two different residential environment settings. The result of the research is that different spatial patterns will affect children's play behavior patterns during distance learning, children's responses to spatial patterns, structure and character of environmental settings in play activities. The behavior and responses of different children become the design reference and produce basic data about the effect of pattern of greeting on children's playing behavior. Subsequent research on elements of the playroom in the New Normal.Abstrak: Kegiatan pembelajaran anak-anak sekolah pada masa pandemik Covid 19 ini dilaksanakan dengan metode Pembelajaran Jarak Jauh (PJJ). Pembelajaran Jarak Jauh secara tidak langsung merubah perilaku anak baik saat belajar maupun saat bermain. Pembatasan kegiatan dan ruang bermain anak-anak sekolah selama Pembelajaran Jarak Jauh merupakan suatu perubahan yang harus dihadapi semua anak-anak termasuk anak-anak yang tinggal di Perumahan. Pattern of Space dan setting lingkungan khususnya lingkungan perumahan berpengaruh besar terhadap perilaku bermain anak. Penelitian ini menggunakan metode deskriptif kualitatif yaitu menganalisis melalui komparasi data hasil survey dan observasi langsung dari dua setting lingkungan perumahan yang berbeda. Hasil penelitian adalah pola ruang yang berbeda akan mempengaruhi pola perilaku bermain anak-anak selama pembelajaran jarak jauh, respon anak-anak terhadap pola ruang, struktur dan karakter setting lingkungan dalam kegiatan bermain. Perilaku dan respon anak-anak yang berbeda menjadi acuan desain dan menghasilkan dasar data tentang pengaruh pattern of sapace terhadap perilaku bermain anak. Penelitian selanjutnya mengenai elemen ruang bermain dimasa New Normal.
Gleditsia aquatica, Water Locust
Authors: Andreu Michael G. , Friedman Melissa H. , Northrop Robert J. 
Published: January 2022

Gleditsia aquatica, Water Locust (FOR301/FR369)
Water locust’s wide, spreading root system and affinity for hydric conditions makes it a useful specimen for erosion control on wet banks of freshwater systems. While not widely available, planting this tree in residential yards or other public locations may be less than ideal, since the long and sharply pointed thorns on the main trunk and branches can be hazardous. This deciduous tree is native to Florida. This 2-page fact sheet was written by Michael G. Andreu, Melissa H. Friedman, and Robert J. Northrop, and published by the UF Department of School of Forest Resources and Conservation, July 2012.
http://edis.ifas.ufl.edu/fr369
Florida Fertilizer Label
Authors: Sartain Jerry B. 
Published: January 2022

Revised! SL-3, a 5-page fact sheet by J.B. Sartain, is included in the Florida Lawn Handbook and the Florida Master Gardener Handbook. It describes the information required by law to be shown on the fertilizer label in Florida. Published by the UF Department of Soil and Water Science, October 2008.

SL-3/SS170: The Florida Fertilizer Label (ufl.edu)