bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fabrication of ceramic tube‐supported tetraethyl‐orthosilicate cross‐linked polydimethylsiloxane membranes for separation of furfural–water mixture by pervaporation technology
Authors: Lin Tong Hoang , Toai Phan Thi Danh , Tinh Ninh Thi , Phat La Nam , Huong Le Minh , Viet Nguyen Duc , Dat Nguyen Minh , Nam Hoàng Minh , Phong Mai Thanh , Hieu Nguyen Huu 
Published: March 2022

AbstractIn this study, polydimethylsiloxane/tetraethyl‐orthosilicate (PDMS/TEOS) hybrid materials with different TEOS ratios were synthesized by cross‐linking method. Ceramic tube‐supported PDMS/TEOS membranes were fabricated by dip‐coating method. Effect of TEOS content, feed concentration, and feed temperature through separation of a furfural–water mixture by pervaporation (PV) technology was investigated. The highest PV performance was obtained with the total flux of 1.19 kg/m2h with TEOS content of 1.8 g, furfural feed concentration of 30 wt.%, operating temperature, and vacuum pressure at 100 kPa and 50 °C, respectively. PDMS/TEOS was successfully synthesized and coated on ceramic tube‐supported with a thickness of 15 μm. The ceramic tube‐supported membrane demonstrated good hydrophobicity with a contact angle of 109.5° and excellent thermal stability at 450 °C. The obtained results demonstrated that the ceramic tube‐supported PDMS/TEOS membrane is potent to be utilized for the separation of the furfural‐water mixture by PV technology.
Vision‐based tracking control of quadrotor for a moving target with nonlinear angular velocity observer
Authors: Zhang Sihang , Ji Haibo 
Published: March 2022

AbstractIn this article, an automatic tracking process for unmanned aerial vehicle (UAV) system to follow the target with maneuverability is developed, and a vision‐based control method is proposed. At first, the image‐based visual servoing (IBVS) position control technology is applied without any prior target information for the algorithm practicability. Besides, consider the situation with unavailable angular velocity measurement, a thorough nonlinear attitude controller with an observer based on contraction is proposed. Finally, the whole UAV system stability is demonstrated to be uniformly ultimately bounded, and the bound can be arbitrarily small. Simulation and experiment results are presented to show effectiveness of the designed controller.
Effects of caffeine ingestion on physiological indexes of human neuromuscular fatigue: A systematic review and meta‐analysis
Authors: Sun Ruishan , Sun Junya , Li Jingqiang , Li Shuwen 
Published: March 2022

AbstractBackgroundCaffeine is often used as a stimulant during fatigue, but the standard of characteristic physiological indicators of the effect of caffeine on neuromuscular fatigue has not been unified. The purpose of this systematic review and meta‐analysis is to summarize current experimental findings on the effects of caffeine on physiological indexes before and after neuromuscular fatigue, identify some characteristic neuromuscular physiological indexes to assess the potential effects of caffeine.MethodsThe Preferred Reporting Items for Systematic Reviews and Meta‐analyses are followed. We systematically searched PubMed, Google academic, and Web of Science for randomized controlled trials. We searched for studies on caffeine's (i) effects on neuromuscular fatigue and (ii) the influence of physiological indexes changes. Meta‐analysis was performed for standardized mean differences (SMD) between caffeine and placebo trials in individual studies.ResultsThe meta‐analysis indicated that caffeine significantly improves voluntary activation (VA) (SMD = 1.46;95%CI:0.13, 2.79; p < .00001), PTw (SMD = 1.11, 95%CI: –1.61, 3.84; p < .00001), and M‐wave (SMD = 1.10, 95%CI: –0.21, 2.41; p < .00001), and a significant difference (p = .003) on measures of Peak Power (PP), and insignificant difference on measures of heart rate (HR) (I2 = 0.0, p = .84) and Maximal oxygen uptake (VO2) (I2 = 0.0, p = .76).ConclusionThe analysis showed that caffeine intake had a relatively large effect on VA, potentiated twitch (PTw), M‐wave, which can be used as characteristic indexes of caffeine's impact on neuromuscular fatigue. This conclusion tends to indicate the effects of caffeine on neuromuscular fatigue during endurance running or jumping or muscle bending and stretching. The caffeine intake had a big effect on the electromyogram (EMG) and peak power (PP), and its effect role needs to be further verified, this conclusion tends to indicate the effect of caffeine on neuromuscular fatigue during jumping or elbow bending moment movements. HR, VO2, maximal voluntary contraction (MVC) cannot be used as the characteristic indexes of caffeine on neuromuscular fatigue. This conclusion tends to indicate the effect of caffeine on neuromuscular fatigue during endurance exercise. However, the results of meta‐analysis are based on limited evidence and research scale, as well as individual differences of participants and different physical tasks, so it is necessary to interpret the results of meta‐analysis cautiously. Therefore, future research needs to explore other physiological indicators and their indicative effects in order to determine effective and accurate characteristic indicators of caffeine on neuromuscular fatigue.
Cervical spine epidural abscess caused by brucellosis: A case report and literature review
Authors: Shafizad Misagh , Ehteshami Saeid , Shojaei Hamidreza , Jalili Khoshnoud Reza 
Published: March 2022

AbstractWe report a rare case of epidural abscess at the cervical 5‐cervical 6 (C5–C6) levels. The patient underwent surgery with complete abscess removal through C6 vertebral body corpectomy. The result of bacteriological culture was Brucella melitensis. Brucellosis must be considered as a possible cause of epidural abscess in patients from endemic area.
Pasireotide use for the treatment of endogenous hyperinsulinemic hypoglycemia refractory to conventional medical therapy: A case report and review of the literature
Authors: Husni Hasan , Khan Sara A. , Alghaieb Buraq , Abusamaan Mohammed S. , Donner Thomas W. , Hamrahian Amir H. 
Published: March 2022

AbstractInsulinomas are rare neuroendocrine pancreatic tumors that can be associated with severe episodes of hypoglycemia, leading to significant morbidity and mortality. These tumors are often difficult to localize, and hypoglycemia control can be challenging since glucose levels can be resistant to conventional therapies. Pasireotide is a novel somatostatin analog with a high affinity to multiple somatostatin receptors. It has up to 40 times higher affinity for somatostatin receptor subtype 5 in comparison with octreotide, leading to a higher inhibition of insulin release from beta cells. There are few case reports regarding the use of pasireotide in refractory hyperinsulinemic hypoglycemia. We describe a challenging case of endogenous hyperinsulinemic hypoglycemia refractory to standard medical treatment, in which pasireotide was used. In this case, imaging studies and calcium stimulation testing failed to localize an insulin‐secreting tumor in an 83‐year‐old woman. Glucose levels remained low despite treatment with diazoxide, verapamil, and octreotide, necessitating the use of IV dextrose solutions. After starting subcutaneous (SC) pasireotide 0.9 mg twice a day, there was a significant improvement in the frequency and severity of hypoglycemic events, allowing the patient to be discharged from the hospital without needing IV glucose support.
Nickel Nanoparticles Encapsulated in Nitrogen‐Doped Carbon Nanofibers as Excellent Bifunctional Catalyst for Hydrogen and Oxygen Evolution Processes
Authors: Aleksandrzak Malgorzata , Dymerska Anna , Maslana Klaudia , Kukulka Wojciech , Suchenia Sara , Chen Xuecheng , Mijowska Ewa 
Published: March 2022

AbstractThe potential of nitrogen‐doped carbon nanofibers with encapsulated Ni nanoparticles as a bifunctional catalyst in H2 and O2 evolution reactions (HER and OER, respectively) was studied. The proposed heterostructure is fabricated via a facile chemical vapor deposition on Ni supported on graphitic carbon nitride (GCN) as a precursor. HER was an effect of photocatalytic water splitting and catalytic dehydrogenation of lactic acid used as sacrificial electron donor. However, photocatalysis played the dominant role in the acceleration of the reaction rate which was 17 times and 330 times higher in respect to the sample prior the CVD and to pristine GCN, respectively. The catalyst exhibited boosted electrocatalytic activity in OER and outstanding stability in respect to RuO2 in alkaline medium. The overpotentials calculated from linear sweep voltammetry at 10 mA cm−2 is ∼383 mV for the fabricated electrocatalyst in respect to 490 mV for the RuO2 and Tafel slope is calculated to be 106 mV dec−1 in comparison to 136 mV dec−1 for the reference which is above the state‐of the‐art bifunctional catalysts reported to date. The results reveal that the catalytic processes were boosted due to several key effects such as enhanced visible light absorption, better charge carriers transfer and separation, increased free charge carrier concentration and higher reducing ability of electrons.
Esterification of Acetic Acid with Methanol and Simultaneous Product Isolation by Liquid‐Liquid Extraction in a Taylor‐Couette Disc Contactor
Authors: Rudelstorfer Georg , Neubauer Maximilian , Siebenhofer Matthäus , Lux Susanne , Grafschafter Annika 
Published: March 2022

AbstractIsolation of carboxylic acids from dilute aqueous effluents can be achieved by the combination of liquid‐phase catalyzed reaction with liquid‐liquid extraction. Exemplarily the heterogeneously catalyzed esterification of acetic acid with methanol, accelerated with a cation‐exchange resin and simultaneous transfer of the product methyl acetate into the solvent ShellSol T, was successfully performed in a Taylor‐Couette disc contactor (TCDC) in batch operation mode. Stable three‐phase flow (liquid‐liquid‐solid) was confirmed in lab scale. The conversion of acetic acid in a TCDC operated in batch mode compares well with conversion in a batch reactor.
Tumor‐associated macrophages and risk of recurrence in stage III colorectal cancer
Authors: Cavalleri Tommaso , Greco Luana , Rubbino Federica , Hamada Tsuyoshi , Quaranta Maria , Grizzi Fabio , Sauta Elisabetta , Craviotto Vincenzo , Bossi Paola , Vetrano Stefania , Rimassa Lorenza , Torri Valter , Bellazzi Riccardo , Mantovani Alberto , Ogino Shuji , Malesci Alberto , Laghi Luigi 
Published: March 2022

AbstractTumor‐associated macrophages (TAMs) have a unique favorable effect on the prognosis of colorectal cancer (CRC), although their association with stage‐specific outcomes remains unclear. We assessed the densities of CD68+ and CD163+ TAMs at the invasive front of resected CRC stage III CRC from 236 patients, 165 of whom received post‐surgical FOLFOX treatment, and their relationship with disease‐free survival (DFS). Associations between macrophage mRNAs and clinical outcome were investigated in silico in 59 stage III CRC and FOLFOX‐treated patients from The Cancer Genome Atlas (TCGA). Biological interactions of SW480 and HT29 cells and macrophages with FOLFOX were tested in co‐culture models. Low TAM densities were associated with shorter DFS among patients receiving FOLFOX (CD68+, p = 0.0001; CD163+, p = 0.0008) but not among those who were untreated. By multivariate Cox analysis, only low TAM (CD68+, p = 0.001; CD163+, p = 0.002) and nodal status (CD68+, p = 0.009; CD163+, p = 0.007) maintained an independent predictive value. In the TCGA cohort, high CD68 mRNA levels were associated with better outcome (p = 0.02). Macrophages enhanced FOLFOX cytotoxicity on CRC cells (p < 0.01), and drugs oriented macrophage polarization from M2‐ to M1‐phenotype. Low TAM densities identify stage III CRC patients at higher risk of recurrence after adjuvant therapy, and macrophages can augment the chemo‐sensitivity of micro‐metastases.
Frail young adult cancer survivors experience poor health‐related quality of life
Authors: Pranikoff Sarah , Ayer Miller Vanessa L. , Heiling Hillary , Deal Allison M. , Valle Carmina G. , Williams Grant R. , Muss Hyman B. , Nichols Hazel B. , Smitherman Andrew B. 
Published: March 2022

BackgroundYoung adult cancer survivors experience frailty and decreased muscle mass at rates equivalent to much older noncancer populations, which indicate accelerated aging. Although frailty and low muscle mass can be identified in survivors, their implications for health‐related quality of life are not well understood.MethodsThrough a cross‐sectional analysis of young adult cancer survivors, frailty was assessed with the Fried frailty phenotype and skeletal muscle mass in relation to functional and quality of life outcomes measured by the Medical Outcomes Survey Short‐Form 36 (SF‐36). z tests compared survivors with US population means, and multivariable linear regression models estimated mean SF‐36 scores by frailty and muscle mass with adjustments made for comorbidities, sex, and time from treatment.ResultsSixty survivors (median age, 21 years; range, 18‐29) participated in the study. Twenty‐five (42%) had low muscle mass, and 25 were either frail or prefrail. Compared with US population means, survivors reported worse health and functional impairments across SF‐36 domains that were more common among survivors with (pre)frailty or low muscle mass. In multivariable linear modeling, (pre)frail survivors (vs nonfrail) exhibited lower mean scores for general health (−9.1; P = .05), physical function (−14.9; P < .01), and overall physical health (−5.6; P = .02) independent of comorbid conditions.ConclusionsMeasures of frailty and skeletal muscle mass identify subgroups of young adult cancer survivors with significantly impaired health, functional status, and quality of life independent of medical comorbidities. Identifying survivors with frailty or low muscle mass may provide opportunities for interventions to prevent functional and health declines or to reverse this process.Lay Summary

Young adult cancer survivors age more quickly than peers without cancer, which is evidenced by a syndrome of decreased resilience known as frailty.

The relationship between frailty (and one of its common components, decreased muscle mass) and quality of life among young adult cancer survivors was examined.

Measuring decreased muscle mass and frailty identifies young survivors with poor quality of life, including worse general health, fatigue, physical function, and overall physical health, compared with nonfrail survivors.

Interventions to address components of frailty (low muscle mass and weakness) may improve function and quality of life among young adult cancer survivors.
Controlled One‐pot Synthesis of PdAg Nanoparticles and Their Application in the Semi‐hydrogenation of Acetylene in Ethylene‐rich Mixtures
Authors: Delgado Jorge A. , Benkirane Olivia , de Lachaux Suzanne , Claver Carmen , Ferré Joan , Curulla‐Ferré Daniel , Godard Cyril 
Published: March 2022

AbstractIn the present paper, we report the synthesis of highly functionalized nanomaterials carefully nanoengineered to catalyze the semi‐hydrogenation of acetylene in ethylene‐rich mixtures. Surface functionalization and structure modification of a series of bimetallic PdAg nanoparticles was performed using HHDMA as stabilizer and alloying the active palladium phase with silver. Bimetallic PdAg NPs with adjustable Pd/Ag ratio were prepared in water through a novel one‐pot methodology using hydrogen gas as a benign reducing agent and cyanide as additive. UV‐Vis studies indicated the formation of the bimetallic nanostructures through a sequential displacement‐galvanic reduction process mediated by cyanide. The series of colloidal NPs were deposited onto alumina and successfully applied as catalysts in the selective hydrogenation of acetylene in ethylene rich mixtures. Geometric and electronic promotion of Ag over Pd based catalysts was evidenced by the increase of the ethylene selectivity with the Ag content. The reactivity of these materials demonstrated the applicability of HHDMA stabilized NPs in a gas phase reaction of industrial interest and the success of combining several strategies for the enhancement of the alkene selectivity.
Synthesis of Truncated Carbocyclic Nucleosides Using 5′‐Deoxy‐5′‐Heteroarylsulfonylnucleosides
Authors: Oka Natsuhisa , Kanda Mayuka , Furuzawa Minami , Arai Wakaba , Ando Kaori 
Published: March 2022

AbstractThis article describes the detailed protocol for the synthesis of “truncated” carbocyclic nucleosides with a cyclopentene core and without a 4′‐hydroxymethyl group. The synthesis was performed using 5′‐deoxy‐5′‐heteroarylsulfonylnucleosides, which were prepared by the 5′‐O‐mesylation of the appropriately protected nucleosides, followed by a nucleophilic substitution with heteroarylthiols and the oxidation of the resulting 5′‐S‐heteroaryl‐5′‐thionucleosides. The treatment of the 5′‐deoxy‐5′‐heteroarylsulfonylnucleosides with 1,8‐diazabicyclo[5.4.0]undec‐7‐ene affords the truncated carbocyclic nucleosides, presumably via a domino reaction involving the α‐deprotonation of the heteroarylsulfone, elimination of the nucleobase, formation of an α,β‐unsaturated sulfone, Michael addition of the nucleobase to the α,β‐unsaturated sulfone, and an intramolecular Julia‐Kocienski reaction. This protocol would be useful for the short‐step synthesis of biologically active carbocyclic nucleosides. © 2022 Wiley Periodicals LLC.Basic Protocol 1: Preparation of 5′‐deoxy‐5′‐heteroarylsulfonylnucleosidesBasic Protocol 2: Synthesis of truncated carbocyclic nucleosides
An integrated equalization charger for series‐connected energy storage cells
Authors: Yang Xiaoguang , Jia Zhe , Wang Dexin , Nie Baoxin , Zhao Xiaobing , Su Yukui 
Published: March 2022

SummaryThis paper proposes an integrated equalization charger that integrates the charger, module‐level equalizer, and cell‐level equalizer into the energy storage system, which greatly simplifies the system. The proposed control strategy can not only improve the equalization charging characteristics of the system, such as fast balancing speed and high efficiency, but also enable all active switches to achieve zero voltage switching (ZVS) operation. The established analytical models and control block diagram facilitate the design and development of the converter. The proposed converter can balance the cells while charging the string. An experimental prototype was developed, and the experimental results verified the theoretical analysis and demonstrated the characteristics of the proposed converter.
Diverging conditions of current and potential future urban forest patches
Authors: Doroski Danica A. , Bradford Mark A. , Duguid Marlyse C. , Hallett Richard A. , Pregitzer Clara C. , Ashton Mark S. 
Published: March 2022

AbstractForested natural areas in cities provide a range of social, ecological, economic, and health benefits. Ensuring the delivery of these benefits requires an understanding of current and potential future forest conditions, yet urban forest dynamics are not well‐understood. Here, we address this knowledge gap by examining forest structure and composition in 126 plots distributed across three forest patch sizes (large [95–126 ha], medium [1–19 ha], and small [0.05–0.65 ha] patches) in the city of New Haven, CT. We detected significant shifts in forest structure and composition suggesting a suite of distinct successional trajectories within each patch size. Large patches comprised 95% native tree species in the canopy (>5 cm dbh), sapling (1–5 cm dbh), and seedling (<1 cm dbh) layers, suggesting that these large patches will continue to be native‐dominated in the future—a primary objective for urban forest management. Moreover, in these large patches, shifts in the dominant species in each stratum suggest that as large patches move through succession they will transition from moderately shade‐tolerant forest types (i.e., oaks) to shade‐tolerant types (i.e., American beech)—a similar successional trajectory to surrounding second‐growth forests in the region. Medium patches were the most heterogeneous patch size sampled. Despite this heterogeneity, they generally resembled large patches in the canopy and sapling layers but diverged in the seedling layer. In medium patches, the invasive Norway maple replaced American beech as primary seedling species suggesting a future shift toward non‐native‐dominated forest in the future. Small patches were the most compositionally and structurally distinct patch size sampled. Only 36% of the canopy trees and saplings in small patches were native species; however, this increased to 71% native in the seedling layer. Additionally, the most important seedling species included those that are bird‐dispersed highlighting the potentially valuable role that these small, non‐native, forest fragments play as wildlife corridors. Collectively, our study demonstrates that multiple forest types, dynamics, and conditions can be found within a single city and that forest patch size offers a helpful framework to begin to parse out these differences.
Robust action and scenarios: A rejoinder
Authors: Rowland Nicholas J. , Spaniol Matthew J. 
Published: March 2022

AbstractThis article is a rejoinder in response to commentaries written about a 25‐year retrospective on Kees van der Heijden's seminal text Scenarios: The Art of Strategic Conversation. As a means to explore the commentaries and—without irony—bring them into conversation with one another, this piece engages in a thought experiment about the impact of Scenarios as well as the book's author through the sociologically informed notion of robust action from traditional thinking about social embeddedness.
The long‐term effect of the Earned Income Tax Credit on women's physical and mental health
Authors: Jones Lauren E. , Wang Guangyi , Yilmazer Tansel 
Published: March 2022

AbstractUsing a novel method, and data from the National Longitudinal Survey of Youth 1979 (NLSY79), we estimate the cumulative, long‐term, causal effect of Earned Income Tax Credit (EITC) eligibility on women's physical and mental health at age 50. We find that an increase in lifetime eligible EITC benefits is associated with long‐term improvements in physical health, such as reduced occurrence of activity‐limiting health problems and reduced reported diagnoses of mild and severe diseases. We explore intermediate health behaviors and outcomes, and find that an increase in lifetime eligible EITC benefits increases the number of hours worked and access to employer‐sponsored health insurance, and decreases body mass index in the short‐term. We find no significant effects of the EITC on mental health at age 50. Finally, we find that White women benefit disproportionately from the EITC in terms of mobility‐related health issues, while Black and Hispanic women benefit in terms of lung‐related illnesses like asthma, as well as cancer and stroke.