bluuebunny/crossref_metadata_2025_split huggingface dataset:
Laparoscopic pectopexy with native tissue repair for pelvic organ prolapse
Authors: Yu Pei , liu chongdong 
Published: November 2022

Abstract
Purpose
The use of mesh for vaginal repair is currently problematic; consequently, there is increased interest in native tissue repair. Combining native tissue repair with sufficient mesh-applied apical repair might provide effective treatment. We describe the study focusing on the combination of pectopexy and native tissue repair.
Methods
Between April 2020 and November 2021, 49 patients with symptomatic stage III or IV were treated with laparoscopic pectopexy combined with native tissue repair. The mesh was solely used for apical repair. All other clinically relevant defects were treated with native tissue repair. The perioperative parameters including surgical time, blood loss, hospital stay, and complications were recorded. The anatomical cure rate was evaluated according to the Pelvic Organ Prolapse Questionnaire (POP-Q) assessment. Validated questionnaires of the Pelvic Floor Distress Inventory (PFDI-20), and the Pelvic Floor Impact Questionnaire (PFIQ-7), were recorded to evaluate the symptom severity and quality of life.
Results
The mean duration of follow-up was 15 months. All domains of POP-Q, PFDI-20, and PFIQ-7 scores improved significantly after surgery. No major complications, mesh exposure, or mesh complication occurred during the follow-up period.
Conclusion
Laparoscopic pectopexy combined with native tissue repair, resulting in favorable clinical findings, is an effective surgical method.
Existence and Stability Results of Non-local Integro-Differential Boundary Value Problems with Hilfer Derivative
Authors: S Naveen , V Parthiban 
Published: November 2022

Abstract
The existence and stability results of nonlocal integro-differential boundary value problemswith Hilfer derivative of order ω ∈ (1, 2) have been investigated. A new definition of thefractional derivative was introduced by R. Hilfer. He named it as the left-sided (right-sided)generalized Riemann-Liouville (R-L) derivative of order ω ∈ (0, 1) and a type τ ∈ [0, 1]. Manyauthors call it the Hilfer derivative. Such derivative interpolates between the R-L and Caputoderivative. The fixed point theorems of Banach and Schaefer are two commonly used fixedpoint theorems that are applied to our results. To demonstrate the effectiveness and applicabilityof our theoretical conclusions and two-step Lagrange polynomial interpolation were usedto solve three numerical results and their application is used in the last part.
Perceptions and experiences of diploma nursing students towards clinical learning and teaching. A qualitative study
Authors: Jacob Angela , Munyaw Yuda , Seif Saada 
Published: November 2022

Abstract
Background: The quality of nursing education depends largely on the experience student receive in the clinical environment. The learning environment is complex with factors that may positively or negatively influence students learning. The study aimed to explore the experiences and perceptions of diploma nursing students toward their clinical learning and teaching.
Methods: A qualitative phenomenological study design was employed. A purposive sampling using a criterion strategy was applied to enroll participants. Focus-group discussions were conducted to collect the data and a thematic analysis was done.
Results: A total of 32 Participants were enrolled from 4 schools, 19 were females and the age ranged from 19 to 25 years. Four main themes emerged during the discussions, which were unsatisfactory clinical supervision and teaching, drawbacks to clinical learning and teaching, insufficient clinical educational planning, and confusion about nursing professional identity.
Conclusion: From students' perspectives, the main challenges during clinical placements are unsatisfactory supervision, student congestion in wards, poor planning of rotations, and confusion about nursing professional identity. Regarding these challenges, students perceived negative impacts on clinical learning.
Predictability of intraoral scanner error for full-arch implant-supported rehabilitation
Authors: Zingari Francesco , Meglioli Matteo , Gallo Francesco , Macaluso Guido Maria , Tagliaferri Sara , Toffoli Andrea , Ghezzi Benedetta , Lumetti Simone 
Published: November 2022

Abstract
Objectives
The present study aimed to analyze the behaviors of three intraoral scanners (IOSs): evaluating the interdistance and axial inclination discrepancies in full-arch scans, predictable errors were searched.
Materials and Methods
Six edentulous sample models with variable numbers of dental implants were used; reference data were obtained with a coordinate-measuring machine (CMM). Each IOS performed 10 scans per model (180 total scans). The origin of each scan body was used as a reference point to measure interdistance lengths and axial inclinations. Precision and trueness of interdistance measurements and axial inclinations were evaluated to address error predictability. Bland–Altman analysis, followed by linear regression analysis and Friedman’s test (plus Dunn’s post hoc correction), was performed to evaluate the precision and trueness.
Results
Regarding interdistance, Primescan showed the best precision (mean±SD: 0.047±0.020mm), while Trios3 underestimated the reference value more than the others (p < 0.001) and had the worst performance (mean±SD: −0.079±0.048mm).
Concerning the inclination angle, Primescan and Trios3 tended to overestimate angle values, while CS3600 underestimated them. Primescan had fewer inclination angle outliers, but it sporadically added 0.2–0.4° to the measurements.
Conclusions
IOSs showed predictable errors: they tended to overestimate or underestimate linear measurements and axial inclinations of scan bodies, one added occasionally 0.2-0.4° to the angle inclination values. In particular, they showed heteroscedasticity, a behavior probably related to the software or the device itself.
Clinical Significance
The presence of constant errors and unique heteroscedastic behavior were demonstrated for the first time.
Comparison of the Prognostic Value of Four Nutritional Indices in Heart Transplantation
Authors: Yao Dingyi , Xu Li , Wang Yixuan , Liu Yuqi , Chen Yuqi , Tu Jingrong , Xia Tian , Li Fei , Chen Si , Shi Jiawei , Dong Nianguo 
Published: November 2022

AbstractPurpose The purpose of this article was to evaluate and compare the prognostic value of four different nutrition indices in heart transplantation (HTx). Methods A total of 438 patients who underwent THx from January 2015 to December 2020 were included in this study. These four nutritional indices are CONUT (Controlling Nutritional Status), NRI (Nutritional Risk Index), GNRI (Geriatric Nutritional Risk Index) and TCBI (Triglycerides, Total Cholesterol, and Body Weight Index). The outcome variables included postoperative complications and all-cause death. Multivariate logistic and Cox regression models were used to evaluate the relationship between these four nutrition indices and adverse clinical outcomes. Results The CONUT score was found to be independently correlated with the length of total postoperative stay (OR, 1.788; 95% CI, 1.119–2.854; p = 0.015) and posttransplant infection (OR, 1.634; 95% CI, 1.050–2.542; p = 0.029). The NRI was also an independent risk factor for posttransplant infection (OR, 0.606; 95% CI, 0.400-0.917; p = 0.018). However, no significant difference was observed in the cumulative incidence of all-cause death between the low and high CONUT, NRI, GNRI and TCBI groups. Conclusion None of these nutritional indices were associated with survival in HTx, but the preoperative CONUT and NRI might be valuable in predicting the postoperative complications of HTx.
Pulmonary function test induction jacket - A device that reduces effort-related challenges during the forced vital capacity manoeuvre
Authors: Rajdeep Prashant , Poorey Ketaki , Patel R. K. , Oommen E. R. 
Published: November 2022

Abstract
The pulmonary function test (PFT) induction jacket was invented to make the process of performing the forced vital capacity (FVC) manoeuvre with a computerized spirometer effortless and productive for both the patient and the medical practitioner. The jacket is composed of three layers of PVC material sealed together to form a single jacket with two chambers. The inner chamber is formed between the inner layer and the middle layer, in which cold water at a temperature of 10 °C is circulated using a connected water unit when triggered. Similarly, the outer chamber is formed between the middle layer and the outer layer, in which air is pressurized using a connected air unit. Thirty volunteers performed the FVC manoeuvre with and without wearing the jacket. There was no difference between the results in spirometry parameters in the participants without a jacket and those with a jacket. However, use of the jacket significantly reduced the number of trials the participants had to undergo to successfully perform spirometry. The jacket has automated the FVC manoeuvre by triggering a physiological inspiratory gasp using cold water and circumscribing pressurised air for expiration. Additionally, subsequent advancements in the jacket have been suggested.
Internal Electric Fields in Asymmetric Single-layer Lattices for Enhancing Photocatalytic Solar-to-Hydrogen Efficiency
Authors: Liu Yuliang , Wan Feng , Li Bo , Lv Xingshuai , Yang Chuan-Lu , Shi Ying 
Published: November 2022

Abstract
Two-dimensional materials with intrinsic internal electric field possess promising potential to improve the photocatalytic water-splitting performance. However, the construction of the internal electric field is still a great challenge, which requires that the material itself should exhibit spontaneous symmetry breaking with intrinsic polarization. Herein, we propose using a general intercalation approach to introduce spontaneous polarization electric field into single-layer lattice by constructing the spatially asymmetric configurations. Taking septuple-atomic-layer MoSi2N4 as a model material, following the above design principle, four promising MSi2N3Y (M= Mo, W; Y=P, As) monolayers are theoretically identified, exhibiting excellent stabilities, suitabilities and low reaction barriers for overall water splitting. Importantly, the intrinsic internal electric field of MoSi2N3Y promotes the charge-carrier separation and improves the light absorption capacity simultaneously, thus enabling the high solar-to-hydrogen efficiency of 29.84%−32.93%. This study opens up an avenue to rationally engineer the internal electric field and contributes to enhance the photocatalytic efficiency.
Secure Exam Storage Using RSA public key encryption
Authors: Tarawneh Monther , AlZyoud Faisal , Sharrab Yousef , Tarawneh Omar , husni Moath 
Published: November 2022

Abstract
Performance, usability, and security are the focus of software systems development. Confidentiality, availability and integrity are the main goals of these systems security. One common software system that needs to be secured is exams, which is an assessment method to measure student performance in education. Sharing exams between faculty members is common task for moderation and review, but it exposed to Leakage. Exams Leakage will affect confidentiality and integrity of the exams. Loss of confidentiality will affect the reputation of the institute, where loss of integrity may have serious impact on the students’ performance. It is a troublesome for faculties to guarantee exam electronic documents confidentiality. Therefore, it is required to have secure exam storage systems. Some solutions are central server-based systems, cloud-based systems, and block chain-based systems. The cloud-based system is secure and trusted, but data may corrupt without the knowledge of the cloud service provider. Bock chain is a better solution but requires more storage. In this paper, we proposed a key management method to secure exams storage using public key Cryptosystem; it uses an RSA algorithm to provide distinctive feature of data integrity, confidentiality and authentication. It can be used in centralised server-based system or cloud-based system. The proposed framework provides security without increase in encoding and decoding time and without increase in file size.
Emerging Challenges of AI for Biomedical Image Analysis: A CBCT image noise reduction method based on cGAN
Authors: Shi Weili , Miao Yu , Zhang Chengcheng , Ding Yifei , Shi Lemin , Li Mingye , Wang Wei 
Published: November 2022

Abstract
Background

As an imaging modality, cone beam CT (CBCT) is widely employed in dentistry, which can help dentists to observe tissues such as roots and jaws without confusion. CBCT has the advantages of convenience and low radiation dose, however low contrast and large noise are the critical issues in the images. These disadvantages make it difficult for dentists to identify target tissues accurately. Due to the differences in scanning methods and reconstruction algorithms between CBCT and multi-row detector spiral CT (MDCT), the current CT noise reduction models present significant shortcomings in terms of reducing the noise on CBCT images.

Results

In this paper, we propose a method of image noise reduction based on a conditional generative adversarial network to improve the quality of CBCT images. The normal-dose MDCT images are used as the ground truth images for model training to generate the denoised images. In order to increase the model’s sensitivity to the gradient information, a gradient loss function is involved in our proposed method. The verification experiments on the simulated data set and the real data set show that our model effectively generates denoised images as well as preserves the quality of the images. We compare the denoising effect between our model and other models with different loss functions. The scores by PSNR, MS-SSIM and GMSD show that our model presents better edge characteristics and a denoising effect.

Conclusion

Through the experiments, the performance of our improved cGAN for denoising in oral CBCT data are better than the compared with other models in terms of evaluation score and visual quality. Our model is more competitive for clinical application. Comparing with other models which only reduce simulated noise, we directly input CBCT images to reduce the noise.
The recovery time of hypothalamic-pituitary-adrenal axis after curative surgery in Cushing’s disease and its predictor
Authors: Zhang Shuo , Cui Qiaoli , Liu Xiaoyu , Sun Quanya , Sun Wanwan , Zheng Hangping , He Min , Zhang Zhaoyun , Ma Zengyi , Shen Ming , Shou Xuefei , Zhao Yao , Li Yiming , Wang Yongfei , Ye Hongying 
Published: November 2022

Abstract
Objective

Patients with Cushing’s disease (CD) experienced transient central adrenal insufficiency (CAI) after successful surgery. However, the reported recovery time of hypothalamic-pituitary-adrenal (HPA) axis varied and the risk factors which could affect recovery time of HPA axis had not been extensively studied. This study aimed to analyze the duration of CAI and explore the risk factors affecting HPA axis recovery in post-operative CD patients with biochemical remission.

Design and methods

Medical records of diagnosis with CD in Huashan Hospital were reviewed between 2014 and 2020. 140 patients with biochemical remission and regular follow-up after surgery were enrolled in this retrospective cohort study according to the criteria. Demographic details, clinical and biochemical information at baseline and each follow-up (within 2 years) were collected and analyzed.

Results

Overall, 103 patients (73.6%) recovered from transient CAI within 2 years follow-up and the median recovery time was 12 months [95% confidence intervals (CI): 10–14]. The age and midnight ACTH at baseline were significantly lower, while the TT3 and FT3 levels were significantly higher in patients with recovered HPA compared to patients with CAI at 2-year follow-up(p < 0.05). In persistent CAI group, more patients underwent partial hypophysectomy. TT3 at diagnosis was an independent predictor of the recovery of HPA axis, even after adjusting for gender, age, duration, surgical history, maximum tumor diameter, surgical strategy, and postoperative nadir serum cortisol level (p = 0.04, OR: 6.03, 95% CI: 1.085, 22.508). Among patients with unrecovered HPA axis at 2-year follow-up, 23 CAI patients (62%) were accompanied by multiple pituitary axis dysfunction besides HPA axis, including hypothyroidism, hypogonadism, or central diabetes insipidus.

Conclusion

HPA axis recovered in 73.6% of CD patients within 2 years after successful surgery, and the median recovery time was 12 months. TT3 level at diagnosis was an independent predictor of postoperative recovery of HPA axis in CD patients. Moreover, patients coexisted with other hypopituitarism at 2-year follow-up had a high probability of unrecovered HPA axis.
Interfacial photochemistry of light-blown bubbles produced via photolysis
Authors: Zhang Dianwen 
Published: November 2022

Abstract

UV light can create and grow bubbles (herein referred to as IPBs for interfacial photoinduced-reaction bubbles) at liquid/solid interfaces through photoinduced reactions that produce gases. Unlike the simple experience of blowing water bubbles through a straw, in which the bubbles quickly move away from their nucleation sites, not only can a deep UV laser beam create IPBs in liquid acetone, but also it can hold and grow them and even capture nearby free bubbles. Raman measurement revealed that the gases in the IPBs include C2H6, CO and H2, and in liquid acetone sp2-carbon species were detected upon the UV excitation. Time series Raman measurement discloses a photocarbonization process in which small acyclic carbon species gradually form small clusters with carbon rings and eventually produce a large piece of amorphous carbon at the top of an IPB in pure liquid acetone. The photocarbonization may open new avenues for development of carbonaceous materials.
A Cross-Sectional Study of Plasma Manganese and Selenium Levels in Paediatric CKD Patients
Authors: Verma Subhrata , Belostotsky Vladimir , Yang Liju , Filler Guido 
Published: November 2022

Abstract
Introduction: Manganese (Mn) and Selenium (Se) deficiencies are noted in adult patients with chronic kidney disease (CKD). However, levels of these trace elements have not been well studied in the pediatric CKD population. We determined the Mn and Se levels in a single-institution cohort of paediatric patients with CKD.
Methods: Ancillary cross-sectional study to a prospective longitudinal randomized control trial on zinc supplementation, which included 42 children and adolescents aged 0 to 19 years with CKD stages I to IV not on dialysis, who had 1-6 trace element measurements. Cystatin C estimated glomerular filtration rate (eGFR) was calculated using the Filler formula. Plasma Mn and Se levels were measured, and anthropomorphic data/blood parameters were collected from electronic health records.
Results: There were 96 Mn and Se levels in 42 patients. The median Mn concentration was 12.61 nmol/L [10.08, 16.42] with a trend towards lower values with lower eGFR (p=0.0367 one-sided). Mn z-scores were significantly lower than the general paediatric reference population. The mean Se level was 1.661±0.3399 µmol/L with a significant positive correlation with eGFR (p=0.0159, r=0.366). However, only 4 patients with low eGFR had abnormally low Se levels.
Conclusion: This single-institution ancillary study of children with CKD demonstrates a significant decrease in Se levels with decreasing eGFR, but no significant difference between mean Se z-scores of our cohort and the reference population. There was no significant relationship between Mn levels and eGFR however the mean Mn z-score was significantly lower than the theoretical mean.
Clinical Trial Registration: clinicaltrials.gov, NCT02126293, https://clinicaltrials.gov/ct2/show/NCT02126293. Date: April 30, 2014
Effect of lateral deformations of a simply-supported beam bridge on high-speed railway traffic safety under earthquake action
Authors: huang wei , Sun Yuehan , Li Binghui , Zhang Qiang , Shao Junhu , Zhan Yulin 
Published: November 2022

Abstract

To study the influence of the lateral deformations of a simply-supported beam bridge on the safety of high-speed railway train operations under earthquake action, this study adopted a three-span simply-supported beam bridge with 32-m spans as an example. Finite element software ANSYS and multi-body dynamics software SIMPACK were used to establish a coupled train-bridge dynamic model subjected to seismic excitations. By adopting different ground motions and changing the peak ground acceleration (PGA) and the train speed, the effects of different earthquakes and train speeds on the train driving safety were analyzed. Several conclusions were obtained. First, the trends in train derailment coefficient, wheel load reduction rate, lateral horizontal wheelset forces, vertical accelerations of the car body, lateral accelerations of car body, and other dynamic indices were similar under different ground motions, but the actual values were different. Second, the PGA had a significant impact on the train derailment coefficient, wheel load reduction rate, lateral horizontal wheelset forces, and lateral accelerations of the car body, but little effect on the vertical accelerations of the car body. Third, the train speed affected the train derailment coefficient, wheel load reduction rate, lateral horizontal wheelset forces, vertical accelerations of the car body, and lateral accelerations of the car body, and these dynamic performance indices were positively correlated with the train speed. Fourth, in case of the earthquake with a PGA of 0.3g, a high-speed train would have to travel slower than at 280 km/h to ensure the safety and comfort of the ride.
Optimal Time-Fixed Impulsive non-Keplerian Orbit to Orbit Transfer
Authors: Bucchioni Giordana , Lombardi Francesco , Bellome Andrea , Leitao Joao-Pedro Fernandes , Innocenti Mario , Lizy-Destrez Stèphanie 
Published: November 2022

Abstract
The work proposes a systematic method to compute an optimal transfer trajectory between two non-Keplerian halo orbits in the Circular Restricted Three body formulation of the Earth-Moon dynamics. The paper exploits the knowledge of the natural non-linear dynamics and the primer vector theory applied to the Circular Restricted Three Body Problem to design optimal Halo-to-Halo transfers with fixed and limited, compared with the rest of the literature, Time of flight, from every point of the departure orbit to every point of the arrival orbit. With the goal