bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of a Comic Book Intervention in Preventing Second-hand Smoke Exposure for Pregnant Indonesian Women: A Randomised Controlled Trial
Authors: Inaoka Kimiko , Octawijaya Ishak Halim , Mamahit Citra Gabriella , Karundeng Jeand’arc Florentia , Wariki Windy Mariane Virenia , Ota Erika 
Published: May 2022

Abstract
This randomised controlled trial evaluated the effectiveness of a comic book intervention to promote second-hand smoke (SHS) avoidance among pregnant women and appropriate smoking behaviours among their male partners. We allocated 140 couples to the experimental group (EG) and 146 couples to the control group (CG), who received usual care. The primary outcome was women’s self-reported SHS exposure and their male partners’ smoking behaviours. Secondary outcomes included knowledge and awareness of SHS. Independent t-tests revealed that three months post-intervention, more male partners in the EG intended to quit smoking (t-test (df = 205) = 2.12, MD = .24, p-value = .035). Significantly more pregnant women in the EG recognised their partners’ intentions to quit smoking (t-test (df = 205) = 2.72, MD = .30, p-value = .007), reported that they distanced themselves from smoking (t-test (df = 210) = 2.09, MD = 0.19, p-value = .038), and avoided exposure to SHS (t-test (df = 184) = 2.30, MD = .02, p-value = .023). These findings suggest that a comic book intervention might be effective against SHS exposure by providing several cues to action through knowledge and awareness of SHS.
What do we want to get out of this? A critical interpretive synthesis of the value of process evaluations with a practical planning framework
Authors: French Caroline , Dowrick Anna , Fudge Nina , Pinnock Hilary , Taylor Stephanie JC 
Published: May 2022

Abstract
Background
Process evaluations aim to understand how interventions bring about outcomes by examining intervention mechanisms, implementation, and context. While much attention has been paid to the methodology of process evaluations in health research, the value of process evaluations has received less critical attention. We aimed to unpack how value is conceptualised in process evaluations and identify and critically analyse 1) how process evaluations may create value and negative consequences, 2) themes of value, and 3) tensions between values.
Methods
We systematically searched for and identified published literature on process evaluation, including guidance, opinion pieces, primary research, reviews, and discussion of methodological and practical issues. We conducted a critical interpretive synthesis and developed a practical planning framework.
Results
We identified and included 147 literature items. From these we determined three sources of value (or potential negative consequences) created by process evaluations: 1) socio-technical processes of ‘doing’ the process evaluation, 2) characteristics of the knowledge produced by process evaluations, and 3) how process evaluation knowledge is used. From these three sources of value, we identified 15 value themes. Value varies according to the characteristics of individual process evaluation and is subjective and context dependent.
Conclusion
The concept of value in process evaluations is complex and multi-faceted. Stakeholders in different contexts may have very different expectations of process evaluations and the value that can and should be obtained from them. We propose a planning framework to support an open and transparent process to plan and create value from process evaluations and negotiate trade-offs. This will support the development of joint solutions and, ultimately, generate more value from process evaluations to all.
Robot-assisted radial forearm free flap harvesting: A propensity score-matched case-control study
Authors: Shin Seung-Woo , Kim Hyounmin , Nam Woong , Kim Hyung Jun , Cha In-Ho , Koh Yoon Woo , Kim Dongwook 
Published: May 2022

Abstract
Although some surgeons prefer anterolateral thigh and latissimus dorsi flap for soft tissue reconstruction in head and neck area because it minimizes donor site complications, radial forearm flap remains the workhorse for soft tissue reconstruction due to its reliability. To reduce donor site morbidity, the authors developed a novel technique for radial forearm flap harvesting using a robotic device. 42 radial forearm free flap reconstruction cases were studied, consisting of 31 conventional and 11 robot-assisted cases. 1:1 propensity score matching was done according to age, sex, previous and postoperative radiation therapy history and method used for vein anastomosis. There were no significant difference was in flap outcome, which was 100% vitality in the robot-assisted group and 90.9% vitality in the conventional group. The robot-assisted group showed significantly longer mean harvesting time than did the conventional group, being 107.2 minutes and 67.0 minutes respectively. Robot-assisted radial forearm flap harvesting can reduce donor site complications by minimizing incision. When more surgical experience is gained under appropriate case selection, we expect our robot-assisted method will yield a harvesting time similar to that of the conventional method and thus become more reliable and feasible.
What do patients and their carers experience in a lung cancer referral pathway? a qualitative study.
Authors: Otty Zulfiquer , Evans Rebecca , Larkins Sarah , Sabesan Sabe , Brown Amy 
Published: May 2022

Abstract
Background: Lung cancer referral pathways aim to reduce delays and improve referral patterns of people with suspected lung cancer. As part of implementing lung cancer referral pathway at a regional Australian hospital, this study aimed to explore the experiences and perceptions of people with lung cancer and their carers.Methods: In-depth interviews were used to elicit data for thematic analysis in this cross-sectional qualitative study. Newly diagnosed lung cancer patients and their carers at an academic cancer centre were invited to participate in interviews. Five interviews were conducted face-to-face, and fourteen interviews were conducted by telephone (as per interviewee preference). Interviews were audio-recorded, transcribed, and qualitatively analysed. Descriptive phrases were used to generate initial inductive codes and themes. Results: Nineteen out of 36 participants approached agreed to take part in the study. Important aspects for participants identified were: quality of communication from clinicians, timeliness of investigations and specialist referrals, patient advocacy, psycho-social support, and co-ordination of care. Various difficulties experienced which reduced their perception of quality of care were reported by some patients and their carers. Tele-health consultations, including telephone consultations, were being used widely due to the COVID 19 pandemic. Factors which positively impacted the care experience were good communication, timeliness and patient advocacy and support. Improper communication, long waiting times for investigations and appointments, uncertainty about the process and inconsistent providers negatively impacted the care experience. Participants preferred face to face or video-linked consultations over telephone consultations.Conclusions: Proper communication, timeliness and adequate psycho-social support were perceived as important factors in improving satisfaction of lung cancer patients and their carers during the referral pathway. Methods to improve communication by clinicians, reduce delays and provide support care during the referral pathway should be explored further.
Optimised Extreme Gradient Boosting Model for Short Term Electric Load Forecasting: Application to the French Regional Grid
Authors: Qinghe ZHAO , Wen XIANG , Boyan HUANG , WANG Jong , FANG Junlong 
Published: May 2022

Abstract
Load forecast provides effective and reliable guidance for power construction and grid operation. It is essential for the power utility to forecast the exact in-future coming energy demand. Advanced machine learning methods can support competently for load forecasting, and extreme gradient boosting is an algorithm with great research potential. We take the extreme gradient boosting algorithm as the original model and combine the Tree-structured Parzen Estimator method to design the TPE-XGBoost model for completing the high-performance single-lag power load forecasting task. We resample the power load data of the Île-de-France Region Grid provided by Réseau de Transport d'Électricité in the day, train and optimise the TPE-XGBoost model by samples from 2016 to 2018, and test and evaluate in samples of 2019. The optimal window width of the time series data is determined in this study through Discrete Fourier Transform and Pearson Correlation Coefficient Methods, and five additional date features are introduced to complete feature engineering. By 500 iterations, TPE optimisation ensures nine hyperparameters’ values of XGBoost and improves the models obviously. In the dataset of 2019, the TPE-XGBoost model we designed has an excellent performance of MAE = 166.020 and MAPE = 2.61%. Compared with the original model, the two metrics are respectively improved by 14.23% and 14.14%; compared with the other eight machine learning algorithms, the model performs with the best metrics as well.
Improving medical student recruitment into neurosurgery through teaching reform
Authors: Shen Jun , Yuan Lili , Ge Ruixiang , Shao Xuefei , Jiang Xiaochun 
Published: May 2022

Abstract
Objective: This study aimed to determine whether a combination of case-based learning (CBL) and problem-based learning (PBL) methods in teaching can improve the academic performance and recruitment of medical students for neurosurgery.Methods: Four classes of fourth-year medical students were randomly divided into two groups. The traditional model group received the traditional teaching method, and the CBL-PBL group received the combined teaching methods of CBL and PBL. After the courses, the differences between the two groups in self-perceived competence, satisfaction with the course, postclass test scores, and clinical practice abilities were compared, and the proportions of neurosurgery major selection in pre- and postcurriculum between the two groups were also analyzed.Results: Self-perceived competence, postclass test scores, and clinical practice abilities in the CBL-PBL group were significantly better than those in the traditional model group. The students in the CBL-PBL group showed a higher degree of satisfaction with the course than those in the traditional model group. At the end of the semester, the proportion of students who chose neurosurgery majors in the CBL-PBL group increased significantly.Conclusion: Compared with the traditional teaching method, the CBL and PBL integrated method is more effective for improving the performance of medical students and enhancing their clinical capabilities in neurosurgery teaching. The CBL-PBL method effectively improved students’ interests in neurosurgery, potentially contributing to increasing medical student recruitment into neurosurgery.
A Case Report of the Identification of Catheter Pinch-Off Syndrome in a Chest X-Ray by Nurse Specialist
Authors: GAO LI , ZHANG Hanfeng , LUO LEI 
Published: May 2022

Abstract
Introduction Pinch-off syndrome (POS) can lead to intravascular embolization so it is very important to predict POS in advance. POS is easily misdiagnosed as catheter catheter obstruction, most of the cases are diagnosed by radiologists or clinicians observe whether the catheter is narrowed or broken on chest radiographs,but fewer cases are reported in which catheter stenosis is identified on chest radiographs by nurse specialist alone.Methods We discuss the case which thetotally implantable venous access devices (TIVADs) was dysfunctional but it was not being addressed correctly in many medical Settings until the patient came to our hospital.Results The nurse specialist in the vascular access nursing clinic discovered POS and helped the patient manage it timely. The TIVADs were removed safely under digital subtraction angiography (DSA).Conclusions It is necessary for medical staff to increase their awareness of catheter pinch-off syndrome and to prevent and treat TIVAD, thus avoiding serious complications.
Synthesis of Diverse Spiro-imidazo Pyridine-indene Derivatives via Acid-Promoted Annulation Reaction of Bindone and Heterocyclic Ketene Aminals
Authors: Nasri Shima , Bayat Mohammad , Miankooshki Fatemeh Rostami 
Published: May 2022

Abstract
A new multi-component reaction for the synthesis of novel and diverse spiro-imidazo pyridine-indene derivatives named spiro[imidazo[1,2-a]indeno[2,1-e]pyridine-5,1'-indene and indenylidene-1H-spiro[imidazo[1,2-a]pyridine-7,1'-indene was successfully developed by the reaction between heterocyclic ketene aminals (generated from 1,1-bis(methylthio)-2-nitro ethylene and diamine) and [1,2′-biindenylidene]-1′,3,3′-trione (bindone) (in situ generated from self-condensation of 1,3-indandion) by using malononitrile as a promoter or as one of the precursors respectively in the presence of p-TSA as the acid catalyst in EtOH as reaction medium under reflux conditions. Depending on whether the reaction is single-step or two-step, malononitrile can act as a promoter or reactant. The convenient one-pot operation, straightforward isolation without using additional purification methods, and the use of a variety of diamines and cysteamine hydrochloride causing a variety of structural products are attractive aspects of the present approach. The synthesized final product contains active methylene and this active site can be involved in further reactions to synthesize more complex heterocycles.
Characterization and discrimination of two varieties of eggplants using multi-element and metabolomics profiles with chemometrics
Authors: Niu Xuemei , Mi Si , Jin Qiuxia , Sang Yaxin , Wang Xianghong 
Published: May 2022

Abstract
The main purpose of the present study was to clarify the differences present in the multi-element and metabolite profiles between two varieties of eggplants. A total of 54 elements were identified by inductively coupled plasma mass spectrometry, 16 elements were significantly different between peel (n = 3) and flesh (n = 3). Besides, untargeted metabolomics combined with chemometric approach based on UHPLC-Q-TOF/ MS was used to identify the peel (n = 4) and flesh (n = 4).178 metabolites were screened with criteria of p < 0.05, fold change > 1.5 or < 0.67 and variable importance > 1 for the PLS-DA model prediction score. Amino acid compounds, maltitol and Kaempferol 3-O-rutinoside are the most important identification components of the two varieties of eggplant. Results showed that the two varieties of eggplants could be distinguished based on their multi-element and metabolite profiles, which may provide new directions for eggplant function research.
Transcriptome analysis reveals key genes and pathways associated with the petal color formation in cabbage (Brassica oleracea L. var. capitata)
Authors: Zhang Bin , Wang Jiao , Chen Li , Ren Wenjing , Han Fengqing , Fang Zhiyuan , Yang Limei , Zhuang Mu , Lv Honghao , Wang Yong , Ji Jialei , Zhang Yangyong 
Published: May 2022

Abstract

Petal color is an important agronomic trait in cabbage (Brassica oleracea L. var. capitata). Although the key gene BoCCD4 has been functionally characterized, the underlying molecular regulatory mechanism of petal color formation in cabbage is still unclear. In this study, we applied the transcriptome analysis of yellow petals from the cabbage inbred line YL-1 and white petals from the Chinese kale inbred line A192-1 and BoCCD4-overexpressing transgenic line YF-2 (YL-1 background), which revealed 1928 DEGs common to both the A192-1 vs. YL-1 and the YL-1 vs. YF-2 comparison groups. One key enzyme-encoding gene, BoAAO3, and two key TF-encoding genes, Bo2g151880 (WRKY) and Bo3g024180 (SBP), related to carotenoid biosynthesis were significantly up-regulated in both A192-1 and YF-2 petals, which was consistent with the expression pattern of BoCCD4, indicating that these key genes may interact with BoCCD4 to jointly regulate carotenoid biosynthesis in cabbage petals. This study provides new insights into the molecular regulatory mechanism underlying petal color formation in cabbage.
The role of Atlantic variability in modulating the tropical cyclone formation in the Australian region
Authors: Zhang Shuo , Ma Ming , Li Ming , Chen Jian , Bai Chengzu 
Published: May 2022

Abstract
Previously the interannual variability of tropical cyclone genesis (TCG) in the Australian region has mainly been attributed to the climate variability in the Pacific and Indian Oceans. In this study, we found that the influence from climate variability in the Atlantic is of equal importance. Application of a state-of-the-art causality analysis reveals that the Atlantic meridional mode (AMM), Atlantic multidecadal oscillation (AMO) and north tropical Atlantic (NTA) sea surface temperature (SST) anomalies are all causal to the Australian region TCG frequency. The associated physical mechanisms are investigated as well. Based on this causal analysis and inference, a statistical model is constructed to forecast TCG, using the Poisson regression and the step-by-step predictor selection method. The Atlantic causal factors, after being taken in as new predictors, help increase the forecast skill for the seasonal Australian region TCG by as much as 10% in terms of correlation increase and 40% in terms of root-mean-square error reduction.
Based on AMPK/mTOR/ULK1 pathway to explore the molecular mechanism of autophagy and the intervention effect of esmolol in septic myocardial injury
Authors: Liu Maoxia , Qin Yan , Li Zheng-da , Jin Jun , Zhang Yan-bing , Yang Xin-jing 
Published: May 2022

Abstract
Purpose
Autophagy is a double-edged sword. The purpose of this study was to investigate the signal transduction pathway of esmolol (ES) interfered with lipopolysaccharide (LPS)-induced cardiomyocyte autophagy.
Methods
Sepsis was induced by intraperitoneal injection of LPS (10mg/kg) in male Sprague- Dawley rats (250–300) g, which were treated with ES (15mg/kg·h), 3-methyladenine (3-MA, 15mg/kg) and rapamycin (RAP, 4mg/kg) respectively for twelve hours. The severity of myocardial necrosis was analyzed by hematoxylin- eosin (HE) staining. The expression quantity of autophagy protein in myocardial tissue was detected by Western blotting.
Results
LPS-induced increase in the expression of p- mTOR as well as decrease in the expression of LC3-II, Beclin-1, p-AMPK and p-ULK1 was also inhibited by pretreatment with ES or rapamycin (agonists of autophagy). On the contrary, 3-MA didn’t play a role in enhancing LPS-induced autophagy inhibition.
Conclusion
This study suggests that ES may provide a new strategy for treatment of sepsis cardiomyopathy through activating the AMPK/mTOR/ULK1 signal pathway-regulated autophagy.
New MDS Self-Dual Codes From Two Disjoint Subsets
Authors: Cao Yuting , Zhu Shixin 
Published: May 2022

Abstract
In recent years, some new classes of MDS self-dual codes were construed. The method is to obtain new structure by generalized GRS codes. In this paper, our idea is to construct MDS self-dual codes of length n where is composed with two subgroups of Fq. In particular, these two subgroups do not intersect. Several classes of new q-ary MDS self-dual codes under specific conditions are given by considering the intervalof s, t.
Evaluation of factors affecting the reduction in pelvic floor muscle tension and the therapeutic effect
Authors: Zou Jinghui , Liu Yan , Xue Aijiao , Sun Xiaohuan , Zhang Yisheng 
Published: May 2022

Abstract
Purpose This study investigated the risk factors associated with reductions in pelvic floor muscle tension and evaluated improvements in pelvic floor muscle tension with electrical stimulation combined with biofeedback technology and Kegel exercises.Methods We conducted a case-control study of 170 women with postpartum follow-up at Ningbo Li Huili Hospital from April 2019 to May 2020. According to the MOS, 94 and 76 women were included in the abnormal pelvic floor muscle tension group and control group, respectively. The two groups were trained by pelvic floor training. The changes in pelvic floor muscle tension before and after treatment in the two groups were analyzed to evaluate the effect of postpartum pelvic floor rehabilitation training.Results The EMG value of the fast muscle contraction stage was negatively correlated with age and neonatal weight (P <0.05). The EMG values of slow muscle contraction and endurance were negatively correlated with weight gain during pregnancy but positively correlated with age and BMI at delivery (P <0.05). The muscle tension of the abnormal muscle tension group was significantly improved and significantly higher than that of the control group (P <0.05) after the two groups received the intervention.Conclusion The factors affecting postpartum pelvic floor muscle tension include age, delivery times, BMI at delivery and neonatal weight. Electrical stimulation combined with the biofeedback technique and Kegel exercises in the early postpartum period are effective means to reduce the incidence of PFD.
An experiment to distinguish persistent infrasounds from two fumaroles at Kirishima Iwo-Yama
Authors: Yamakawa Kazuya , Ichihara Mie , Muramatsu Dan , Matsushima Takeshi , Takahashi Hidetoshi , Wada Ruka , Shimoyama Isao 
Published: May 2022

Abstract
In the infrasonic observation of fumarolic area, the challenge is to distinguish among the multiple fumarolic sources and noise. The array technique effectively estimates the source locations and identifies the target signal from others and noise. We conducted the experiment at Kirishima Iwo-yama, Japan, where there are two fumarolic craters separated by about 450 m. A three-element array with an aperture of 20 m was installed between two targeting fumaroles. In addition, a single microphone was installed near one of the fumaroles. The array with the waveform correlation analysis estimated the most prominent source but failed to estimate the other weak source. The joint analysis of the array and the single microphone effectively resolved the two sources. The method developed by this experiment would be beneficial for monitoring volcanoes that hold hydrothermally active multiple vents.