bluuebunny/crossref_metadata_2025_split huggingface dataset:
The key success factors to adopting lean practices: the case of South American manufacturing firms
Authors: Ferrer Mario , Calvo Erick , Santa Ricardo 
Published: November 2022

PurposeThe purpose of this paper is to identify the factors that promote the successful adoption of lean practices in manufacturing firms operating in developing economies in South America.Design/methodology/approachBased on the results obtained from using structural equation modeling to analyze the collected data, the authors argue that manufacturing organizations need to identify the factors that assist in successfully adopting lean practices in manufacturing firms operating in developing economies in South America. A dataset of 1,809 responses, gathered from manufacturing firms as part of the World Management Survey, was used to find support for the proposed hypotheses.FindingsSeveral hypotheses were tested finding that lean practice success factors such as organizational targets proved to have a significant and positive relationship with the mediating factor, performance management. Likewise, performance management was also found to have a significant and positive relationship with lean practices adoption. Human capital management (HCM) has a significant but negative predictive relationship with lean practices.Research limitations/implicationsThe empirical results of this study provide valuable managerial insights. The results are therefore limited to the economies analyzed and to the variables surveyed as part of the World Manufacturing Survey research.Practical implicationsThe results of this research provide a starting point for researchers to continue studying the key lean practice factors and relationships in the achievement of improved performance management, thereby helping managers in developing strategies to improve the lean capabilities of their practices. This, in turn, will increase the organization's competitive advantage sustainably.Originality/valueThis paper identifies and tests the impact of key factors on successful lean practices adoption in South American organizations in the manufacturing sector.
An overview of bitter compounds in foodstuffs: Classifications, evaluation methods for sensory contribution, separation and identification techniques, and mechanism of bitter taste transduction
Authors: Yan Jingna , Tong Huarong 
Published: November 2022

AbstractThe bitter taste is generally considered an undesirable sensory attribute. However, bitter‐tasting compounds can significantly affect the overall flavor of many foods and beverages and endow them with various beneficial effects on human health. To better understand the relationship between chemical structure and bitterness, this paper has summarized the bitter compounds in foodstuffs and classified them based on the basic skeletons. Only those bitter compounds that are confirmed by human sensory evaluation have been included in this paper. To develop food products that satisfy consumer preferences, correctly ranking the key bitter compounds in foodstuffs according to their contributions to the overall bitterness intensity is the precondition. Generally, three methods were applied to screen out the key bitter compounds in foods and beverages and evaluate their sensory contributions, including dose‐over‐threshold factors, taste dilution analysis, and spectrum descriptive analysis method. This paper has discussed in detail the mechanisms and applications of these three methods. Typical procedures for separating and identifying the main bitter compounds in foodstuffs have also been summarized. Additionally, the activation of human bitter taste receptors (TAS2Rs) and the mechanisms of bitter taste transduction are outlined. Ultimately, a conclusion has been drawn to highlight the current problems and propose potential directions for further research.
Effects of a low‐velocity fluvial environment on saw mark evidence in bone
Authors: Grosso Alicia R. , Volney Tyra L. 
Published: November 2022

AbstractSaws are common tools used in postmortem dismemberment to alter human remains. Dismemberment may coincide with other concealment methods such as disposal in aquatic environments, so forensic anthropologists must recognize how taphonomy affects saw mark preservation. This study focuses on exposure of saw cut bone to a fluvial environment. Cross sections from pig humeri cut by a 7 TPI saw were evaluated on all cut surfaces for tooth hop (TH), exit chipping, and breakaway spurs. Pre‐fluvial exposure, features were measured by two observers using a stereomicroscope while a one‐dimensional profilometer was used to define surface roughness. Bones were randomly assigned to control or experimental groups and within each divided by duration of exposure (24, 48, 72, and 96 h). Control groups (four cross sections) were exposed to water in a 3‐meter‐long hydraulic channel; experimental groups (20 cross sections) were exposed to water and sediment in a 12‐meter‐long sediment‐recirculating hydraulic channel. Velocity was maintained at 0.45 m/s. All measurements were repeated post‐exposure. Observer A recorded 268 TH (mean: 3.70 ± 0.34 mm); post‐exposure, count increased by 16.79% (mean: 3.71 ± 0.29 mm). Observer B recorded 247 TH (mean: 3.46 ± 0.42 mm); post‐exposure, count decreased by 29.15% (mean: 3.36 ± 0.33 mm). All TPI estimates calculated include the 7 TPI saw. Exit chipping lost flakiness (in both channels), but was still visible. Breakaway spurs were not visibly altered. Surface staining was limited to bones exposed to sediment. Roughness was significantly lower in experimental groups post‐fluvial exposure (W = 5705, p < 0.05). Overall, this fluvial environment did not obliterate saw mark evidence from bone.
Comparison of the signaling pathways of wing dimorphism regulated by biotic and abiotic stress in the brown planthopper
Authors: Chen Jing‐Xiang , Li Wan‐Xue , Su Qin , Lyu Jun , Zhang Yi‐Bing , Zhang Wen‐Qing 
Published: November 2022

AbstractWing polymorphism is an evolutionary trait that is widely present in various insects and provides a model system for studying the evolutionary significance of insect dispersal. The brown planthopper (BPH, Nilaparvata lugens) can alter its wing morphs under biotic and abiotic stress. However, whether differential signaling pathways are induced by the 2 types of stress remain largely unknown. Here, we screened a number of candidate genes through weighted gene co‐expression network analysis (WGCNA) and found that ornithine decarboxylase (NlODC), a key enzyme in the synthesis of polyamines, was associated with wing differentiation in BPH and mainly responded to abiotic stress stimuli. We analyzed the Kyoto Encyclopedia of Genes and Genomes enrichment pathways of differentially expressed genes under the 2 stresses by transcriptomic comparison, and found that biotic stress mainly influenced insulin‐related signaling pathways while abiotic stress mainly influenced hormone‐related pathways. Moreover, we found that insulin receptor 1 (NlInR1) may regulate wing differentiation of BPH by responding to both biotic and abiotic stress, but NlInR2 only responded to biotic stress. Similarly, the juvenile hormone epoxide hydrolase associated with juvenile hormone degradation and NlODC may regulate wing differentiation mainly through abiotic stress. A model based on the genes and stresses to modulate the wing dimorphism of BPH was proposed. These findings present a comprehensive molecular mechanism for wing polymorphism in BPH induced by biotic and abiotic stress.
Extrusion characteristics of ten novel quinoa breeding lines
Authors: Richter Jana K. , Pietrysiak Ewa , Ek Pichmony , Dey Debomitra , Gu Bon‐Jae , Ikuse Marina , Nalbandian Elizabeth , Żak Angelika , Ganjyal Girish M. 
Published: November 2022

AbstractTen novel breeding lines of quinoa (Chenopodium quinoa Willd) suitable to be grown in the Pacific Northwest of the United States were developed and utilized for extrusion processing. Understanding how a particular breeding line performs during food processing and which properties determine its performance can promote the use of quinoa as an ingredient in value‐added products, such as extruded snacks. In this study, extrusion characteristics of the whole seed flours of the novel quinoa breeding lines were evaluated using a co‐rotating twin‐screw extruder at two temperatures (110°C and 125°C), three screw speeds (200, 350, and 500 rpm), and a moisture content of 18% (w.b.). The expansion ratio (ER) ranged from 1.15 to 2.33 and was negatively influenced by the fat content in the flours. Breeding line 11WAQ‐104.88 (WAQ10) exhibited the greatest potential for use in direct expanded foods as it had the highest ER for all conditions studied. Strong correlations were found between ER and pasting properties of the flours, proving the usefulness of the pasting test for flour quality evaluation before extrusion processing. The results demonstrate the potential of using quinoa for producing direct expanded food products and highlight the importance of selecting specific breeding lines for desired product characteristics.Practical ApplicationThis study provides the extrusion processing characteristics of 10 new quinoa breeding lines. Based on the information gained, it will be easier for the food industry, including breeders as well as processors, to select the right quinoa variety based on their requirements, and may further help to enhance the use of quinoa.
Physics‐based model to predict the acoustic detection distance of terrestrial autonomous recording units over the diel cycle and across seasons: Insights from an Alpine and a Neotropical forest
Authors: Haupert Sylvain , Sèbe Frédéric , Sueur Jérôme 
Published: November 2022

Abstract

Passive acoustic monitoring of biodiversity is growing fast, as it offers an alternative to traditional aural point count surveys, with the possibility to deploy long‐term acoustic surveys in large and complex natural environments. However, there is still a clear need to evaluate how the frequency‐ and distance‐dependent attenuation of sound as well as the ambient sound level impact the acoustic detection distance of the soniferous species in natural environments over the diel cycles and across seasons. This is of great importance to avoid pseudoreplication and to provide relevant biodiversity indicators, including species richness, species abundance and species density.

To address the issue of detection distance, we tested a field‐based protocol in a Neotropical rainforest (French Guiana, France) and in an Alpine coniferous forest (Jura, France). This standardized and repeatable method consists in a recording session of the ambient sound directly followed by an experiment using a calibrated white noise sound broadcast at different positions along a 100 m linear transect. We then used acoustic laws to reveal the basic physics behind sound propagation attenuation.

We demonstrate that habitat attenuation in two different kinds of forests can be modelled by an exponential decay law with a linear dependence on frequency and distance. We also report that habitat attenuation, as first approximation, can be summarized by a single value, the coefficient of attenuation of the habitat.

Finally, we show that the detection distance can be predicted knowing the contribution of each attenuation factor, the coefficient of attenuation of the habitat, the ambient sound pressure level and the amplitude and frequency bandwidth characteristics of the transmitted sound. We show that the detection distance mostly depends on the ambient sound and may vary by a factor of up to 5 over the diel cycle and across seasons. These results reinforce the need to take into account the variation of the detection distance when performing passive acoustic surveys and producing reliable biodiversity indicators.
Informing a position statement on the use of artificial intelligence in dermatology in Australia
Authors: Caffery Liam J. , Janda Monika , Miller Robert , Abbott Lisa M. , Arnold Chris , Caccetta Tony , Guitera Pascale , Shumack Stephen , Fernández‐Peñas Pablo , Mar Victoria , Soyer H. Peter 
Published: November 2022

AbstractArtificial Intelligence (AI) is the ability for computers to simulate human intelligence. In dermatology, there is substantial interest in using AI to identify skin lesions from images. Due to increasing research and interest in the use of AI, the Australasian College of Dermatologists has developed a position statement to inform its members of appropriate use of AI. This article presents the ACD Position Statement on the use of AI in dermatology, and provides explanatory information that was used to inform the development of this statement.
RAB25 coordinates filaggrin‐containing keratohyalin granule maturation and affects atopic dermatitis severity
Authors: Jeong Haengdueng , Lee Nakyum , Uhm Chanyang , Cho Kyungrae , Oh Heeju , Oh Yeseul , Zhang KeLun , Kim Hye Li , Goldenring James R. , Lim Kyung‐Min , Park Chang Ook , Nam Ki Taek 
Published: November 2022

AbstractBackgroundKeratohyalin granules (KHGs) supply the critical epidermal protein constituents such as filaggrin for maintaining skin barrier function during epidermal differentiation; however, their regulating mechanism remains largely unelucidated.MethodsTo investigate the role of Ras‐related protein Rab‐25 (RAB25) expression in skin disease, we utilized skin specimens of patients with moderate‐to‐severe atopic dermatitis (AD) and healthy controls. To investigate the susceptibility of Rab25 knockout mice to AD, we established an oxazolone‐induced AD model.ResultsWe investigated the role of RAB25 in KHG maturation and AD. RAB25‐deficient mice showed a disrupted stratum corneum along with skin barrier dysfunction, decreased KHG production, and abnormal KHG processing. Consistently, in the human keratinocyte cell line HaCaT, RAB25 co‐expressed with filaggrin‐containing KHG and RAB25 silencing impaired KHG formation, which was attributable to abnormal actin dynamics. Most importantly, RAB25 expression was severely downregulated in the skin lesions of patients with AD, which was strongly correlated with disease severity scores.ConclusionsRAB25 coordinates KHG homeostasis by regulating actin dynamics and is critical for epidermal differentiation and the pathophysiology of AD.
Is drug‐induced sleep endoscopy associated with better outcomes after soft tissue surgery for sleep apnea? A systematic review and meta‐analysis
Authors: Lisan Quentin , Baudouin Robin , Lechien Jérôme R. , Hans Stéphane , Blumen Marc 
Published: November 2022

AbstractObjectivesThe aim was to estimate the effect of drug‐induced sleep endoscopy (DISE) on surgical outcomes after soft tissue surgery for obstructive sleep apnea (OSA).Design and SettingSystematic review and meta‐analysis.ParticipantsAdult patients with OSA and candidates for soft tissue surgery, with and without preoperative DISE, were included.Main Outcomes MeasuresA systematic literature search of Medline, Web of Science, and Cochrane databases was performed from inception to December 31, 2021. Studies directly comparing patients with and without preoperative DISE were included. Success rate, change in apnea‐hypopnea index (AHI), change in minimum SpO2 and change in Epworth Sleepiness Scale (ESS) score were extracted. Random‐effect models were used to pool estimates.ResultsSeven out of 619 articles were included, representing 791 patients (389 in the DISE group and 402 in the no DISE group). DISE was neither associated with a higher success rate (pooled OR 1.34, 95% CI 0.69–2.59, p = 0.39) after soft tissue surgery for OSA, nor a significant change in AHI (−4.69 events/hour, 95% CI −11.10 to 1.72, p = 0.15), minimal SpO2 (mean increase of 2.02%, 95% CI −0.26 to 4.29, p = 0.08) and ESS (mean difference of 1.29, 95% CI −0.48 to 3.05, p = 0.15) when compared to patients without preoperative DISE.ConclusionsSoft tissue surgery does not give better results after DISE compared to when DISE is not performed. However, given the overall low level of evidence of included studies, future well‐conducted studies should confirm or overturn these results and clarify the added value of DISE.
Lipid‐Transfer‐Protein‐Allergie: Charakterisierung und Vergleich mit birkenpollenassoziierter Nahrungsmittelallergie
Authors: Wolters Paula , Ostermann Thomas , Hofmann Silke C. 
Published: November 2022

ZusammenfassungHintergrundLipid‐Transfer‐Proteine (LTP) sind ein häufiger Auslöser von Anaphylaxien auf pflanzliche Nahrungsmittelallergene in Südeuropa.Patienten und Methodik15 deutsche Patienten mit LTP‐Allergie wurden verglichen mit 17 Patienten mit birkenpollenassoziierter Nahrungsmittelallergie (BAN) hinsichtlich ihrer detaillierten Anamnese, Serologie, Hauttestungen und der mittels des FAQLQ‐AF Fragebogens erfassten Lebensqualität.ErgebnisseWährend BAN‐Patienten überwiegend auf Baumnüsse und Stein‐ und Kernobst reagierten, berichteten LTP‐Allergiker über Gemüse, Beerenfrüchte, Getreide und Saaten als häufige zusätzliche Auslöser. Bei 73 % der LTP‐Allergiker waren Anaphylaxien mit Kofaktoren assoziiert im Gegensatz zu nur 6 % der BAN‐Patienten (P < 0,001). Symptome traten bei 40 % der LTP‐Allergiker mit einer Verzögerung von mehr als einer Stunde auf und wurden in 86 % durch sowohl rohe wie auch gekochte Nahrungsmittel ausgelöst im Vergleich zu jeweils nur 6 % beziehungsweise 41 % der BAN‐Patienten. Der Pricktest mit Pfirsichextrakt zeigte sich bei allen LTP‐Allergikern, aber nur bei 15 % der BAN‐Patienten positiv (P < 0,001). Obwohl Patienten mit LTP‐Allergie häufiger über schwere Anaphylaxien berichteten, unterschied sich die Lebensqualität von Patienten mit LTP‐Allergie und BAN nicht wesentlich.SchlussfolgerungenAnaphylaxien auf pflanzliche Nahrungsmittel sollten mittels IgE‐Bestimmung gegen Pru p 3 und Hauttests mit Pfirsichextrakt abgeklärt werden, insbesondere im Kontext von assoziierten Kofaktoren und bei Intoleranz auch gegenüber erhitzten Nahrungsmitteln.
Disseminierte papulöse Variante des Morbus Dowling‐Degos: Histopathologische Merkmale bei POGLUT1‐Mutation
Authors: Papadopoulou Katharina , Karsai Syrus , Böer‐Auer Almut 
Published: November 2022

ZusammenfassungDer Morbus Dowling‐Degos ist eine seltene, benigne Genodermatose. Charakteristisch sind lentiginöse Hyperpigmentierungen sowie rotbraune Papeln und Plaques. Häufig sind die Beugeseiten und Intertrigines betroffen, das klinische Bild kann jedoch variieren. Verantwortlich für die klinische Ausprägung sind Mutationen in unterschiedlichen Genen. Während Mutationen im Keratin 5 (KRT5)‐Gen ein retikuläres Verteilungsmuster begünstigen, führen Mutationen im POGLUT1‐Gen zu einem disseminierten, papulösen klinischen Bild. Die akantholytische Variante des Morbus Dowling‐Degos wird historisch als Morbus Galli‐Galli bezeichnet, unsere Falluntersuchung zeigt jedoch, dass die histopathologischen Veränderungen auch innerhalb eines Patienten variieren können. Bisher gibt es kein einheitliches Therapiekonzept. Keratolytische Maßnahmen stehen im Vordergrund, mit unterschiedlich gutem Ansprechen. Neue Therapieansätze mit Hilfe der Lasertechnologie scheinen eine vielversprechende Behandlungsoption zu sein.
COVID‐19 and the Meaning of Crisis
Authors: Abdelrahman Maha 
Published: November 2022

ABSTRACTCrisis is a concept that has a long history; it has come to denote moments of rupture and to foreground life and death decisions necessary for its resolution. The recent deployment of the concept in broad social, economic and political spheres has not only given rise to an industry of crisis management but has also established it as a framework through which to conceive, survive and reconstruct the world. The politics of crisis and the power of crisis narratives determine who is responsible for the crisis, who are its victims, who are its casualties and, inevitably, what policies need to be adopted and, later, institutionalized, in order to ‘fix’ the crisis and its outcomes. This article examines the politics of crisis narratives and situates the contributions to this Debate within larger debates on crisis under capitalism. These contributions employ the COVID‐19 experience as a lens to examine how moments of crisis allow economic and political elites to displace the blame for the crisis and its structural causes away from themselves and to institute policies which maintain the status quo, limit the scope for alternatives to emerge, and foreclose debates on fundamental questions of power relations which, inevitably, reproduce the conditions for future crises.
Cryptogenic posterior circulation stroke in children
Authors: Aripirala Prasanthi , Reddy Nihaal , Lingappa Lokesh , Konanki Ramesh , Varma Dandu Ravi , Raju Subodh 
Published: November 2022

AbstractWe aimed to evaluate the percentage of posterior circulation arterial ischaemic stroke (PCAIS) caused by craniovertebral junction (CVJ) anomalies and describe their clinical course. Children admitted to a tertiary care paediatric hospital with PCAIS between July 2017 and December 2020 were assessed retrospectively for disease aetiology. We reviewed the clinical, radiological, and surgical details of children with evidence of CVJ anomalies. Fourteen (24.1%) of 58 children admitted with arterial ischaemic stroke had posterior circulation involvement. The mean age of patients presenting with posterior circulation stroke was 6 years 6 months (range 3 months–15 years), 11 were male. Six of 14 cases with PCAIS were due to CVJ anomaly, their ages ranged from 4 months to 15 years (two age ranges were noted, 4 months–4 years and 11–15 years), four were male. Two children had atlantoaxial dislocation with basilar invagination, two had Bow Hunter syndrome with Chiari malformation type 1 (one with completed stroke), one had Chiari malformation type 1 alone, and one presented with Farber disease with proatlas segmentation anomaly in CVJ. The time lag to stroke and CVJ diagnosis ranged from 2 weeks to 24 months. A dynamic angiogram was required to evaluate biomechanical changes on scans with inconclusive findings on standard stroke imaging. CVJ anomalies are an important treatable cause of paediatric posterior circulation stroke. Cervical spine x‐ray in flexion and extension should be done in all patients with posterior circulation stroke beyond the acute period. In cryptogenic aetiology, provocative angiography with guarded neck rotation should be considered to evaluate possible dynamic vertebral artery compression.What this paper adds

Craniovertebral junction anomalies are an important cause of posterior circulation stroke in children.
Evidence of flat occiput, short neck, and short stature in children with posterior circulation stroke should be assessed.
Dynamic imaging helps identify dynamic vertebral artery compression.