bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gas Exchange of Oiticica Seedlings in Response to Potassium Fertilization and Water Turning
Authors: Sousa Rosilvam Ramos de , Freire Antonio Lucineudo de Oliveira 
Published: September 2022

Aims: This objective of this work was to evaluate the effects of water deficiency on physiological aspects of oiticica plants, as well as the capacity of potassium fertilization to attenuate such effects.
Study Design: The treatments were distributed in an entirely randomized design (DIC), consisting of a 4x4 factorial, with four levels of potassium (K) and four water turning, with five repetitions.
Place and Duration of Study: The experiment was conducted in a shaded environment, with 50% light interception, in the Forest Nursery of UAEF/UFCG, between January 2020 and July 2020.
Methodology: The relative water content (RWC), transpiration (E) and photosynthesis (A) rates, stomatal conductance (gs), and internal CO2 concentration (Ci) were evaluated, and from the values of A and E, the intrinsic water use efficiency (EUAi) was calculated and, with the data of A and Ci, the carboxylation efficiency (A/Ci).
Results: There was significant interaction of treatments in the parameters RWC, E, gs, A and EUAi and isolated effect of water turning on Ci and A/Ci. Irrigation daily or every five days provided the maintenance of higher water status and better stomatal behavior, and the plants were sensitive to water stress provided by longer water turnings (every 10 and 15 days). The fertilization with 100 and 150 mg dm-3 of K kept the values of E and A high, even under low water availability.
Conclusion: Potassium fertilization proved to be effective in attenuating the negative effects caused by water deficiency on gas exchange and WUEi of the seedlings, with highlights for 100 and 150 mg dm-3 of K levels.
Diversification of Processed Tilapia Fish Products Based on Ecopreneurship to Improve the Quality of Housewife Education Management
Authors: Mahmudah Fitri Nur , Erviana Vera Yuli , Rahayu Wahidah Mahanani 
Published: September 2022

Aims: Improving the ability of housewives to become tilapia farming communities in terms of processed fish.
Study Design: Using One-Shoot Case Study.
Place and Duration of Study: Sample: A farmer group of 40 people in Polaman, Yogyakarta, Indonesia. The time taken is 8 months.
Methodology: The method used is training and mentoring of tilapia processing practices.
Results: All members of farmer groups experienced improvements in skills, knowledge, production, new entrepreneurs, and products sold.
Conclusion: This community service program can run well. The results of the programs given to KWT Sedyo Rahayu have a good opportunity to be used as material for the creation of a new independent business unit. Thus, it can trigger business independence, and economic independence for mothers, and generate better income.
Toxicity of Methanolic Extract of Fruits of Catunaregam spinosa (Rubiaceae) on Danio rerio Embryos
Authors: Lawrence P. K. , Munasinghe M. L. A. M. S. , Senarath W. T. P. S. K. , Suresh Sugandhika 
Published: September 2022

Aims: Catunaregam spinosa is an exotic plant in Sri Lanka. Fruits of this plant contain saponins, steroids, flavonoids possessing piscicidal property. Since years ago C. spinosa employs in the fishery industry, especially in rural areas. This study was established to evaluate the toxicity and the teratogenic effects of fruits of C. spinosa on D. rerio embryos.
Methodology: Semi-static renewal method was conducted to determine the median lethal concentration. Concentrations of 15.0, 17.0, 19.0, 21.0, 23.0 and 25.0 mg L-1 were tested with twenty embryos per treatment. Each concentration was triplicated. Dilution water and 3, 4- Dichloroaniline at 4.0 mg L-1 were tested for negative and positive controls respectively. Four apical observations and teratogenic effects were examined at 24, 48, 72 and 96 h time intervals.
Results: Embryos exposed to 19.5 mg L-1 concentration exhibited 50% mortality at p = 0.05 significance level. Embryos exposed to high concentrations exhibited more teratogenic deformities with a high mortality rate. Negative control recorded >90 % survival rate and positive control 95.0% lethality after 96 h exposure. Hatchability was negatively correlated with the concentration of the extract.
Conclusion: Methanolic fruit extract of C. spinosa showed concentration-dependent mortality and the teratogenic effects on D. rerio embryos. It could be concluded that the fruits of C. spinosa show moderate piscicidal activity.
Impact of Heavy Metal Pollution on the Biotic and Abiotic Components of the Environment
Authors: Ehis-Eriakha C. B. , Akemu S. E. 
Published: September 2022

The environment comprises of biotic and abiotic components interacting as a system. The environment also contains organic and inorganic minerals in optimal concentration required by living organisms for growth, development, and metabolic activities. Due to anthropogenic activities and some natural occurrences, the availability of these elements has drastically increased in the ecosystem beyond the required threshold and permissible limits causing pollution. Heavy metal (HM) is one of the naturally occurring elements that threaten plant, animal, and human health. These HMs have been defined as elements with more than 5gcm-3 relative density that are not readily biodegradable but can be transformed from one state to another and are usually associated with toxicity or ecotoxicity. However, some heavy metals are biologically essential elements required in the body/plant or as constituents of important enzymes although in trace amounts while others are non-essential and are ranked as priority metals due to their high level of toxicity with no biological importance even at low concentrations. The non-degradability property of heavy metals contributes to its persistence and subsequent accumulation in the biota and the food chain which is of public health significance to humans and animals. The soil environment is highly prone to HM contamination due to physiological, biochemical, metabolic, and biogeochemical processes that occur within the environment mostly mediated by microbes. These microbes are inarguably the drivers of ecosystem functioning, although they are significantly the most affected by HM pollution. This review, therefore, describes the ecotoxicological effect of heavy metals with special reference to the soil environment. Other sections discussed are the toxicity and general properties of some selected heavy metal, their role as environmental pollutants and essential elements. In addition, the effect of HM on soil microbes has also been analyzed in two folds: i) reduction in microbial population and diversity and ii) increased diversity and abundance of HM-resistant microbial strains which are significant in bioremediation studies
Photocatalytic Degradation of Malachite Green by NiAl-LDH Intercalated Polyoxometalate Compound
Authors: Hanifah Yulizah , Mohadi Risfidian , Mardiyanto Mardiyanto , Lesbani Aldes 
Published: September 2022

Composites based on layered double hydroxide with polyoxometalate K3[-PW12O40] and K4[-SiW12O40] were synthesized to form NiAl-[SiW12O40] and NiAl-[PW12O40]. The materials were characterized by XRD, FTIR, SEM, and UV-DRS and were then applied as a photocatalyst to degrade MG. The effects of catalyst loading, pH value, and contact times on photodegradation performance were carried out in this study. The results indicated that NiAl-LDH was successfully synthesized by showing the peak diffractions at angles 11.63°, 23.13°, and 35.16°. Both kinds of attained NiAl-[SiW12O40] and NiAl-[PW12O40] had typical structures of LDH that were proved by appearing diffraction at 2θ angles 10.76°, 26.59°, 30.8°, and 63.11° for NiAl-[PW12O40] and at 2θ angles 8.26°, 11.34°, 29°, and 35.1° for NiAl-[SiW12O40]. The materials used for the fifth regeneration were characterized by FTIR, which still presents characteristics of LDH structure. The photocatalyst was applied for the first time to degrade MG. The decrease of band gap on NiAl pristine than LDH composite from 4.76 eV to 3.22 eV for NiAl-[SiW12O40] and 3.78 eV for NiAl-[PW12O40] respectively, was presented by DR-UV analysis. LDH composite shows improved degradation photocatalytic performance in comparison with LDH pristine. It was present by the %degradation MG performances were 68.94% for NiAl LDH, 84.51% for NiAl-[PW12O40]), and 88.91% for NiAl-[SiW12O40]. The degradation percentage indicates that the LDH-polyoxometalate composite has succeeded in increasing the ability of photodegradation catalytic and the regeneration ability of LDH pristine. Copyright © 2022 by Authors, Published by BCREC Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).
Principles of Cutaneous Laser Therapy
Authors: Madan Vishal , Barlow Richard J. 
Published: September 2022

AbstractLasers and light‐based devices have become essential to the management of many dermatoses. Successful treatment is based on the selection of an appropriate device emitting the correct wavelength at a fluence sufficient to damage the target chromophore. In the skin the chromophores are haemoglobin, melanin and water, and this light–tissue interaction forms the basis of treatment. In this chapter, the reader will learn about laser–tissue interactions and indications for cutaneous laser treatments. Patient selection, pain control and complications of treatments are also discussed.
Neurological Conditions Affecting the Skin
Authors: Eedy David J. 
Published: September 2022

AbstractThe relationship between the nervous system and the skin is complex. Neurocutaneous disorders may be divided broadly into those associated with sensory abnormalities, and those associated with autonomic abnormalities, although there is overlap between these two groups. Skin manifestations may occur where the pathology is predominantly located either in the central nervous system or in the peripheral nervous system.
Tumours of Skin Appendages
Authors: Calonje Eduardo 
Published: September 2022

AbstractThis chapter on cutaneous appendageal tumours covers the spectrum of lesions displaying eccrine, apocrine, sebaceous and follicular differentiation. It includes cysts, hamartomas and benign and malignant tumours. Traditionally, appendageal tumours have been classified according to rigid criteria separating lesions with eccrine, apocrine, sebaceous and follicular differentiation. This separation is clearly artificial and it is now acknowledged that lesions regarded as strictly eccrine may well have apocrine differentiation and lesions classified as purely follicular may exhibit apocrine differentiation reflecting the close embryological relationship between the pilosebaceous unit and the apocrine gland.
Subsarcolemmal and cytoplasmic p62 positivity and rimmed vacuoles are distinctive for PLIN4‐myopathy
Authors: Wang Qi , Yu Meng , Zhang Wei , Gang Qiang , Xie Zhiying , Xu Jin , Zhou Chao , Wang Depeng , Meng Lingchao , Lv He , Jia Zhirong , Deng Jianwen , Yuan Yun , Wang Zhaoxia 
Published: September 2022

AbstractPLIN4‐myopathy is a recently identified autosomal dominant muscular disorder caused by the coding 99 bp repeat expansion in PLIN4, presenting with distal or proximal weakness. Here, we report one family and one sporadic case of adult‐onset PLIN4‐associated limb‐girdle weakness, whose diagnoses were achieved by a comprehensive genetic analysis workup. We provided additional evidence that the combination of subsarcolemmal/cytoplasmic ubiquitin/p62 positive deposits and rimmed vacuoles could serve as a strong indicator of PLIN4‐myopathy. Moreover, we found novel myopathological features that were ultrastructural subsarcolemmal filamentous materials and membrane‐bound granulofilamentous inclusions formed by the co‐deposition of disrupted lipid droplets and p62 protein aggregates.
Online continuous time system identification in the presence of impulsive terms
Authors: Belkoura Lotfi 
Published: September 2022

SummaryOnline parameters estimation algorithms are proposed for continuous time systems subject to structured perturbations. Using a distribution framework, a matrix pencil structure, whose polynomial order is characterized by the nature of the singularities describing the impulsive effects, is proposed for the modeling of perturbed systems with different disturbance types. Then, using an appropriate projection subspace, the rectangular pencils are reformulated as square generalized eigenvalue problems subject to linear constraints, from which unperturbed regression are derived. This approach allows for the implementation of recursive estimation schemes, free of penalty terms. An identifiability analysis is also conducted, and theoretical results are illustrated with experimental and simulated data.
Molybdenum Blues with Tunable Light Absorption Synthesized by Femtosecond Laser Irradiation of Molybdenum Trioxide in Water/Ethanol Mixtures
Authors: Ye Fan , Ayub Ahsan , Chang Darren , Chernikov Roman , Chen Qiaoyun , Karimi Reza , Wettig Shawn , Sanderson Joseph , Musselman Kevin P. 
Published: September 2022

AbstractMolybdenum blues (MBs) have attracted increasing attention due to their tunable structures and properties, which make them applicable in numerous fields. In this work, a novel strategy to synthesize MB nanorings by irradiating MoO3 suspended in water/ethanol mixtures with intense femtosecond laser pulses is demonstrated. It is found that the MoO3 can be dissolved in the water during laser irradiation to form molybdic acid, which provides an acidic environment for the formation of MB. Concentrations of ethanol as low as 1% result in the formation of MB and by adjusting the concentration of ethanol in the solvent, the absorption band can be tuned due to the modification of MoVOMoVI entities. The MB synthesized in 30% ethanol appears the darkest blue and assembly of vesicles 115 nm in size is observed. At high concentrations of ethanol (>70%), HXMoO3 and MoO3‐X are preferentially formed instead of MB. The photothermal conversion efficiency of the MBs synthesized in 1% and 30% ethanol is above 40%.
Gold‐Catalyzed Oxygen Transfer to Alkynylsulfones: A Diazo‐Free Route to 4‐Sulfonyl‐1,3‐Oxazoles
Authors: Chikunova Elena I. , Dar'in Dmitry V. , Kukushkin Vadim Yu. , Dubovtsev Alexey Yu. 
Published: September 2022

AbstractThe gold‐catalyzed annulation of alkynylsulfones, involving pyridine N‐oxides (as O‐atom transfer reagents) and nitriles (as C=N synthons), comprises a diazo‐free route to valuable 4‐sulfonyl‐1,3‐oxazoles. This reaction operates under relatively mild conditions (IPrAuNTf2 5 mol %, rt or 60 °C), and a number of functionalities was compatible (35 examples; 14–95%). In most cases, the SO2 fragment, which is typically expulsed in the previously reported Au‐catalyzed O‐transfers to alkynylsulfones, retains in the heterocyclic products. The postulated reaction mechanism suggests a key role of reactive gold α‐oxo carbene intermediates formed via the O‐atom transfer.magnified image
Gold‐Catalyzed Oxyarylation/Hydroxylation of N‐Alkoxypropiolamides for Chemoselective Synthesis of 4‐Aryl‐3‐(2H)‐isoxazolones
Authors: Yasui Motohiro , Tahara Naoko , Matsubara Hiroshi , Takeda Norihiko , Ueda Masafumi 
Published: September 2022

Abstract3‐(2H)‐isoxazolone is an important skeletal structure in medicinal and agricultural chemistry. However, its synthetic methodology has limited substrate scope and requires unconventional substrate synthesis. Meanwhile, gold‐catalyzed intramolecular oxidative cross‐coupling involving the 5/6‐endo‐dig cyclization of substrates bearing an ynone structure has not been reported because of an undesirable protonation as a side‐reaction. Thus, we hypothesized that the reactivity of cyclic N‐alkoxypropiolamides would suppress protonation and allow dual functionalization. As a result, sequential gold‐catalyzed 5‐endo‐dig cyclization, oxidative cross‐coupling, and hydroxylation of N‐alkoxypropiolamides was developed to synthesize 4‐aryl‐3‐(2H)‐isoxazolones with a hydroxy group. In an optimization study, dimethylformamide (DMF) and H2O were effective solvents for the sequential reaction. This method enabled 3‐(2H)‐isoxazolone backbone synthesis with the introduction of an aryl and hydroxy group in a single procedure. Moreover, a tolerance toward reactive functional groups, such as ketocarbonyl groups, was observed. Some chemical transformations of the synthesized 4‐aryl‐3‐(2H)‐isoxazolone were conducted to demonstrate the feasibility of functional group interconversion, C−C bond formation, and additional heterocycle synthesis. Notably, a fluorescent tetracyclic heterocycle was obtained by intramolecular oxidative cross‐coupling. Control experiments indicated that the reactivity for protonation was suppressed by an alkoxyamide moiety. Therefore, the chemoselectivity of oxyarylation was improved. Finally, density functional theory (DFT) calculations were performed to estimate the reaction pathway, which suggested that ring‐opening involving solvents (H2O or DMF) is important for these sequential reactions.magnified image
DNA functionalized plasmonic nanoassemblies as SERS sensors for environmental analysis
Authors: Li Jinxiang , Chen Xueqin , Zhu Jun‐Jie 
Published: September 2022

AbstractSurface‐enhanced Raman scattering (SERS) is among the most widely applied analytical techniques due to its easy execution and extreme sensitivity. Target molecules can be detected and distinguished based upon the fingerprint spectra that arise when absorbed on the SERS substrates surface, particularly on the SERS‐active hotspots. Thus, rational fabricating the enhancing substrates plays a key role in broadening SERS application. Programmable DNA functionalized plasmonic nanoassemblies, where DNA acts as both structure basis and functional unit, combine the specificity of DNA recognition, and modulate the assembly of plasmonic nanoparticles (NPs). Specifically designed DNA not only improves the selectivity to target molecules but also promotes the sensitivity of the optical signals through precisely regulating the distance between the molecule and the substrate. A variety of DNA‐functionalized SERS sensors have been reported and obtained well performance in the analysis of heavy metal ions in water, toxins, pesticide residues, antibiotics, hormones, illicit drugs, or other small molecules. This review places an emphasis on the design and sensing strategies of the DNA‐functionalized plasmonic nanoassemblies, as well as basic principles of Raman enhancement, and recent advances for environmental analysis. The current challenges and potential trends in the development of DNA‐functionalized SERS sensors for environmental pollutant monitoring in complicated scenarios are subsequently discussed.
Newborn screening for Fabry disease in Oregon: Approaching the iceberg of A143T and variants of uncertain significance
Authors: Viall Sarah , Dennis Anna , Yang Amy 
Published: September 2022

AbstractFabry disease newborn screening (NBS) has been ongoing in Oregon for over 41 months by first‐tier enzyme quantitation and second‐tier DNA testing. During that period the majority of abnormal referrals received (34/60) were for the presence of the controversial c.427G > A (p.Ala143Thr) aka A143T and the majority of non‐A143T referrals were for other variants of uncertain significance (17/60) resulting in at least 32 infants with an inconclusive case outcome even after clinical evaluation and/or diagnostic testing. To date there has been no significant family history or onset of symptoms in individuals with an inconclusive outcome. Based on our experience, we have developed a framework for approaching A143T and other variants of uncertain clinical significance in an attempt to balance sensitivity with the unnecessary medicalization of healthy infants.
Confounding factors of Alzheimer's disease plasma biomarkers and their impact on clinical performance
Authors: Pichet Binette Alexa , Janelidze Shorena , Cullen Nicholas , Dage Jeffrey L. , Bateman Randall J. , Zetterberg Henrik , Blennow Kaj , Stomrud Erik , Mattsson‐Carlgren Niklas , Hansson Oskar 
Published: September 2022

AbstractIntroductionPlasma biomarkers will likely revolutionize the diagnostic work‐up of Alzheimer's disease (AD) globally. Before widespread use, we need to determine if confounding factors affect the levels of these biomarkers, and their clinical utility.MethodsParticipants with plasma and CSF biomarkers, creatinine, body mass index (BMI), and medical history data were included (BioFINDER‐1: n = 748, BioFINDER‐2: n = 421). We measured beta‐amyloid (Aβ42, Aβ40), phosphorylated tau (p‐tau217, p‐tau181), neurofilament light (NfL), and glial fibrillary acidic protein (GFAP).ResultsIn both cohorts, creatinine and BMI were the main factors associated with NfL, GFAP, and to a lesser extent with p‐tau. However, adjustment for BMI and creatinine had only minor effects in models predicting either the corresponding levels in CSF or subsequent development of dementia.DiscussionCreatinine and BMI are related to certain plasma biomarkers levels, but they do not have clinically relevant confounding effects for the vast majority of individuals.Highlights
Creatinine and body mass index (BMI) are related to certain plasma biomarker levels.
Adjusting for creatinine and BMI has minor influence on plasma‐cerebrospinal fluid (CSF) associations.
Adjusting for creatinine and BMI has minor influence on prediction of dementia using plasma biomarkers.
DNA‐Encoded Gold‐Gold Wettability for Programmable Plasmonic Engineering
Authors: Zhai Tingting , Zheng Haoran , Fang Weina , Gao Zhaoshuai , Song Shiping , Zuo Xiaolei , Li Qian , Wang Lihua , Li Jiang , Shi Jiye , Liu Xiaoguo , Tian Yang , Shen Jianlei , Fan Chunhai 
Published: September 2022

AbstractControlling the deposition and diffusion of adsorbed atoms (adatoms) on the surface of a solid material is vital for engineering the shape and function of nanocrystals. Here, we report the use of single‐stranded DNA (oligo‐adenine, oligo‐A) to encode the wettability of gold seeds by homogeneous gold adatoms to synthesize highly tunable plasmonic nanostructures. We find that the oligo‐A attachment transforms the nanocrystal growth mode from the classical Frank‐van der Merwe to the Volmer‐Weber island growth. Finely tuning the oligo‐A density can continuously change the gold‐gold contact angle (θ) from 35.1±3.6° to 125.3±8.0°. We further demonstrate the versatility of this strategy for engineering nanoparticles with different curvature and dimensions. With this unconventional growth mode, we synthesize a sub‐nanometer plasmonic cavity with a geometrical singularity when θ>90°. Superfocusing of light in this nanocavity produces a near‐infrared intraparticle plasmonic coupling, which paves the way to surface engineering of single‐particle plasmonic devices.
H+−H− Pairs in Partially Oxidized MAX Phases for Bifunctional Catalytic Conversion of Furfurals into Linear Ketones
Authors: Deng Qiang , Zhou Rong , Zhang Yong‐Chao , Li Xiang , Li Jiahui , Tu Shaobo , Sheng Guan , Wang Jun , Zeng Zheling , Yoskamtorn Tatchamapan , Edman Tsang Shik Chi 
Published: September 2022

AbstractCurrently, less favorable C=O hydrogenation and weak concerted acid catalysis cause unsatisfactory catalytic performance in the upgrading of biomass‐derived furfurals (i.e., furfural, 5‐methyl furfural, and 5‐hydroxymethyl furfural) to ketones (i.e., cyclopentanone, 2,5‐hexanedione, and 1‐hydroxyl‐2,5‐hexanedione). A series of partially oxidized MAX phase (i.e., Ti3AlC2, Ti2AlC, Ti3SiC2) supporting Pd catalysts were fabricated, which showed high catalytic activity; Pd/Ti3AlC2 in particular displayed high performance for conversion of furfurals into targeted ketones. Detailed studies of the catalytic mechanism confirm that in situ hydrogen spillover generates Frustrated Lewis H+−H− pairs, which not only act as the hydrogenation sites for selective C=O hydrogenation but also provide acid sites for ring opening. The close intimate hydrogenation and acid sites promote bifunctional catalytic reactions, substantially reducing the reported minimum reaction temperature of various furfurals by at least 30–60 °C.