bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preliminary Phytochemical Analysis and Invitro Antiplasmodial Activity of Terminalia mantaly Against Plasmodium falciparum
Authors: Usman Bello Muhammad , Attah Daniel Dan-Inna , Kanya Danladi Yusuf 
Published: December 2022

Highlights:

Malaria is prevalent in many populations of communities despite preventive measures.
The experimental was screened for bioactive components which could be the reason for the antimalarial effect and the plant shows dose dependent antimalarial activity.

Abstract :
Malaria has been one of the world’s worst killer diseases throughout recorded human history. Despite attempts to eradicate the disease, it remains a global burden. This could be a result of parasite resistance to current therapy. However, this research aimed at evaluating the in vitro antimalarial activity of ethanolic extracts of Terminalia mantaly on Plasmodium falciparum. The plant extracts were prepared by cold maceration in 70% ethanol and air-dried by a rotary evaporator. The phytochemical analysis was carried out using standard procedures outlined in the Analytical methods of the Association of Official Analytical Chemists (AOAC, 1990) which indicates the presence of tannins, alkaloids, saponins, flavonoids, glycosides, phenol, steroids, and balsam. The in vitro antimalarial assay was carried out according to the method described by WHO (2001). All data were represented as Mean ± Standard deviation. Ethanolic extracts of the three parts of the plant were subjected to in vitro antimalarial activity at three concentrations (300 mg, 150 mg, and 75 mg) in four replicates with artemether (standard drug) as a positive control. Stem bark at 300 mg/kg completely cleared the parasites with a 0.00% parasitaemia rate and there was no significant difference when compared with positive control at p<0.005 value of 1.00. This study affirms the use of the plant for the treatment of malaria.
The Influence of Safety Communications and Safety Promotion Policies on Safety Performance among Nurses in The Emergency Department at a Tertiary Hospital in Surabaya, Indonesia
Authors: Berliana Ratih , Noeroel Widajati  , Nurhayati Saridewi  , Endang Dwiyanti  
Published: December 2022

Highlights:

To reduce the occurrence of work-related accidents, the application of occupational safety and health principles in work activities is necessary.
This research analyzed the safety communications and safety promotion policies on the safety performance among nurses.
Safety communications have influence on safety performance, while safety promotion policies have no influence on safety performance.

Abstract:
The application of the occupational safety and health principles in work activities is expected to reduce the occurrence of work-related accidents. This research was conducted in the Emergency Department of a tertiary hospital of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, in 2019 and aimed to determine the influence of safety communications and safety promotion policies on the safety performance among nurses. This research was a quantitative research with a cross-sectional design study. The population in this study were 208 emergency room nurses at Dr. Soetomo General Academic Hospital with a total sample of 68 people using a simple random sampling technique. The results showed that the correlation between safety communications variable with safety performance had a p-value of 0.035 (<0.05) and the correlation between safety promotion policies variable with safety performance had a p-value of 0.319 (>0.05), indicating that there was an influence of safety communications on safety performance, while there was no influence of safety promotion policies on safety performance among nurses in the Emergency Department of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Healing of Radiation Dermatitis with Ozonated Aloe Vera Oil by Increasing PDGF and Epidermal Thickness in Sprague-Dawley Rats
Authors: Utami Widoasti Putri , Prajoko Yan Wisnu , Christina H.N. Prihharsanti  , Sadhana Udadi , Susilaningsih Neni , Restiwijaya Maryam , Nur Muhammad 
Published: December 2022

Highlights:

This study demonstrated the effect of ozonated Aloe vera oil in the healing of radiation dermatitis wound.
Groups that received no treatment was compared with groups that received treatment using 2.5% hydrocortisone ointment and ozonated Aloe vera.
Ozonated Aloe vera oil improves the healing of radiation dermatitis wound by increasing PDGF expression and epidermal thickness.

Abstract :
The long-term use of corticosteroids as a standard treatment for skin disorders, such as radiation dermatitis, can cause many side effects. Alternatively, ozonated Aloe vera oil may replace corticosteroids due to its fewer side effects and benefits in wound healing process. Re-epithelialization and the formation of growth factors, such as platelet-derived growth factor (PDGF), play an important role in the healing of dermatitis wound. This study intended to demonstrate the effect of ozonated Aloe vera oil to improve the healing of radiation dermatitis wound by increasing PDGF expression and epidermal thickness. This study used a post-test only control group design. A sample of 36 Sprague-Dawley rats was divided into 6 groups (C1=without treatment, C2=2.5% hydrocortisone ointment, P1=pure Aloe vera (AV), P2=300 mg/mL ozonated Aloe vera (OAV), P3=600 mg/mL OAV, P4=1200 mg/mL OAV. The expression of PDGF was assessed using Allred scoring with immunohistochemical staining, whereas the epidermal thickness was assessed using hematoxylin and eosin (H&E) staining at 400x microscopic magnification. The PDGF expression and epidermal thickness between the control and the treatment groups showed significant differences using a Kruskal-Wallis test (P=0.001) and one-way ANOVA test (P<0.001). The groups that was given ozonated Aloe vera oil had higher average of PDGF expression and thicker epidermis than the other groups. The Spearman's correlation test showed a strong positive relationship (p<0.001 and r=0.709) between the two variables. In conclusion, ozonated Aloe vera oil improves healing of radiation dermatitis wound by increasing PDGF expression and epidermal thickness.
Sodium Hyaluronate Eye Drops for College Students with Computer Vision Syndrome in Indonesia
Authors: Zulkarnain Bambang Subakti , Loebis Rozalina , Aryani Toetik 
Published: December 2022

Highlight:

Computer vision syndrome (CVS) that causes dry eyes becomes a health problem for college students.
Sodium hyaluronate eyedrops can be used as one of the CVS therapy strategies for students suffering from CVS.

Abstract:
The use of computers and mobile devices is increasing. Computers and mobile devices help our daily work or study. However, prolonged use of them may cause computer vision syndrome (CVS). Nowadays, CVS becomes a health problem for everyone working with computers or mobile devices including college students because it causes dry eyes. It may disrupt reading, doing professional work, or using a computer which is important for college students to complete academic tasks. Sodium hyaluronate can be used to overcome the dry eye problem due to CVS. To assess the effectiveness of sodium hyaluronate eyedrops on students suffering from CVS, pre- and post-administration of sodium hyaluronate was measured for two weeks. Inclusion criteria for this study were college students aged 20-35 years, using a computer for >2 hours a day, not using nonsteroidal anti-inflammatory drugs (NSAIDs), not consuming drugs, or having a disease that affects tear production and bearing no pregnancy. Parameters assessed include tear break-up time using the Tear Break-Up Time (TBUT) test, tear production using the Schirmer I test, the number of clinically subjective symptoms, and Ocular Surface Disease Index (OSDI) scores. Data were analyzed using student paired t-tests or Wilcoxon Rank Test. There were statistically significant differences before and after the TBUT (4.4 vs 6.7 seconds; p<0.0001); the Schirmer I Test (4 vs 6 mm; p<0.05), and the number of clinically subjective symptoms (3 vs 0 clinically subjective symptoms; p<0.0001). The OSDI scores did not show statistical differences before and after administration of sodium hyaluronate (27 vs 21; p>0.05), but there was a positive impact from moderate to mild dry eye. Sodium hyaluronate eyedrops can be used as one of the CVS therapy strategies for students suffering from CVS.
Efektivitas Penggunaan Layanan Telefarmasi di Era Pandemi COVID-19 dari Perspektif Masyarakat
Authors: Farid Abdul , Firdausy Adelia , Sulaiman Alifia , Simangunsong Dewi , Sulistyani Febi , Varianti Frizca , Ong Kevin , Kristiany Livia , Mustika Nancy , Febiani Natasha , Komalasari Salsabela , Salsabila Salsabila , Azzahra Sherin , Zulfah Yasmin , Aryani Toetik 
Published: December 2022

Pandemi COVID-19 di Indonesia pertama kali diumumkan pada Maret 2020. Kasus COVID-19 yang terus meningkat mendorong pemerintah untuk menetapkan berbagai macam kebijakan untuk menekan angka positif COVID-19 seperti penerapan protokol kesehatan, physical distancing, dan Pemberlakuan Pembatasan Kegiatan Masyarakat (PPKM). Pandemi COVID-19 telah menimbulkan berbagai masalah kesehatan, salah satunya yaitu terhambatnya pelayanan kefarmasian. Oleh karena itu, penerapan telefarmasi di kalangan masyarakat dapat menjadi sebuah pelayanan alternatif demi mengurangi tendensi interaksi aktif secara langsung antara apoteker dengan pasien. Penelitian ini bertujuan untuk mengetahui efektivitas penggunaan layanan telefarmasi di era pandemi COVID-19 dari perspektif masyarakat. Penelitian ini merupakan penelitian Cross-Sectional dengan instrumen berupa kuesioner yang disebar secara online melalui google form. Pengambilan sampel dilakukan secara accidental sampling dengan kriteria inklusi masyarakat umum berusia 15-65 tahun yang berdomisili di Pulau Jawa. Berdasarkan hasil survei terhadap 243 responden, 90 responden (37,03%) pernah menggunakan telefarmasi dan dari 90 responden tersebut semuanya (100%) merasa terbantu dengan adanya pembelian obat secara online, 56 responden (62,2%) menyatakan pelaksanaan pemantauan terapi obat melalui telefarmasi berjalan dengan efektif, 58 responden (64,4%) menyatakan pelaksanaan pemantauan efek samping obat berjalan dengan efektif, dan 72 responden (80%) dapat memahami Informasi obat yang diberikan. Hal ini menunjukkan bahwa penggunaan telefarmasi di era pandemi COVID-19 efektif dari perspektif masyarakat. Namun, pemahaman dan minat masyarakat terkait telefarmasi masih kurang sehingga penggunaannya masih cukup rendah di masyarakat. Untuk itu perlu dilakukan promosi kesehatan terkait telefarmasi agar masyarakat lebih mengenal telefarmasi dan dapat memaksimalkan penggunaanya di era pandemi COVID-19.
IMPACT OF THE COVID-19 PANDEMIC ON THE OPERATIONS OF THE BREAST IMAGING UNIT OF A NON-PANDEMIC HOSPITAL IN TURKEY
Authors: COŞKUN BİLGE Almıla , MUSAPAŞAOĞLU AYDIN Hale , ESEN BOSTANCI Işıl 
Published: December 2022

AIM: We aimed to evaluate changes in patient numbers, procedures performed, and the result of imaging procedures in the breast imaging unit of a non-pandemic hospital in Turkey during the COVID-19 pandemic.
MATERIAL AND METHOD: The study retrospectively evaluated 2010 and 740 patients who presented to our unit in the pandemic and non-pandemic periods, respectively. Patient sex and age, neoadjuvant chemotherapy story, imaging modalities used, final BI-RADS classification, and biopsy and/or wire localization procedures were compared between the periods.
RESULTS: There were significant decreases in the number of patients who presented to our unit and the numbers of mammography, ultrasound, MRI, biopsy, and wire localization procedures performed during the pandemic period (p
Política antidopaje, prensa y franquismo: el caso de la Vuelta a Inglaterra de 1965 = Anti-doping policy, press and Francoism: the case of the Tour of England of 1965
Authors: Font Noguerol Dani 
Published: December 2022

ResumenEn 1965, los ciclistas Luis Pedro Santamarina, Salvador Canet y Jesús Usamentiaga fueron descalificados de la Vuelta a Inglaterra por dar positivo en anfetamina en el control antidopaje. Este artículo pretende analizar la respuesta de los periodistas de ABC y Mundo Deportivo (MD) ante el primer caso de dopaje que implicó a deportistas españoles. Previamente, esos periódicos ya habían informado de casos de dopaje en el ciclismo. La diferencia era que, por vez primera, los acusados eran deportistas de la misma nacionalidad que los periodistas.El caso se enmarca en los inicios de la política antidopaje, poco después de la celebración del primer congreso europeo sobre dopaje celebrado en el Consejo de Europa (CE). Los médicos asistentes al CE, incluidos médicos españoles como Jesús Fernández Cabeza, expresaron su deseo de que los periódicos hiciesen llegar a su audiencia la peligrosidad del dopaje. En general, los periódicos españoles contribuyeron a difundir el discurso científico hegemónico, aunque como analizaremos en esta investigación, la defensa del héroe nacional pasó por encima de los intereses de los portavoces de la política antidopaje. AbstractIn 1965, the cyclists Luis Pedro Santamarina, Salvador Canet and Jesús Usamentiaga were disqualified from the Tour of Britain after a positive test on amphetamine in anti-doping control. This article aims to analyze the response of theABCandMundo Deportivo(MD) journalists to the first case of doping thataffected Spanish athletes. Previously, these newspapers had already reported doping cases in cycling. The difference was that, for thefirst time, the protagonists were athletes of the same nationality as the journalists.The case took place at the beginning of anti-doping policy, shortly after thefirst European Congress on doping held in the Council of Europe (CE). Doctors attending the CE, including Spanish physicians like Jesús Fernández Cabeza, expressed a desire for journalists to bring to their audience the danger ofdoping. In general, Spanish newspapers contributed to the spread of the hegemonic scientificdiscourse based on evidence, although, as we will analyze in this research, the defense of the national hero passed over the interests of the spokesmen of anti-doping policy.
Effect of SO<sub>2</sub>, glutathione and gallotannins on the shelf-life of a Cortese white wine bottled with different oxygen intakes
Authors: Motta Silvia , Tirelli Antonio , Cravero Maria Carla , Guaita Massimo , Bosso Antonella 
Published: December 2022

The work aimed to study the effect of adding reduced glutathione (GSH) and/or gallotannins at bottling on the shelf-life of a Cortese white wine to limit the use of SO2.The experimental trial was carried out following a full factorial plan consisting of 8 experimental trials that differed for the content of free SO2 (2 levels: 20 and 40 mg/L), the absence/presence of gallotannins (0 and 40 mg/L) and GSH (0 and 20 mg/L). The wines of the eight trials were oxygenated respectively at 5.5 ppm and 4.0 ppm of O2. The wines oxygenated at 5.5 ppm were bottled in 135 mL bottles and monitored during 12 months of storage (colour, polyphenolic composition, GSH, free and total SO2); the wines oxygenated at 4.0 ppm of O2 were bottled in 750 mL bottles, then analysed and tasted after 15 months. The oxygen consumption rate (OCR) was measured with a luminescence-based technology. The OCR followed a first-order kinetic in all the wines, and a significant OCR acceleration was observed when increasing the concentration of free SO2. A significant increase in OCR was also observed in the samples with GSH, albeit to a lesser extent than with SO2, while the addition of gallotannins caused a decrease in the OCR. It is possible that similar mechanisms are at the basis of the acceleration of OCR observed with GSH and SO2. However, unlike SO2, GSH showed poor antioxidant efficacy in the protection of both the colour and the aromatic component, probably also due to its lower molar concentration.The presence of GSH limited the oxidative losses of SO2, mostly in wines with higher SO2 levels. However, the effect of GSH decreased over time, since after 8 months, GSH was only present in traces. The resistance to oxidative browning of wines during bottle storage depends on the concentration of free SO2 present in the medium (> 10 mg/L), therefore, higher GSH intakes, such as to ensure sufficient preservation of the free SO2 content during storage, will have to be tested to evaluate the possibility of prolonging the shelf-life of wines.
STRATEGI PENANGGULANGAN BANJIR BERDASARKAN PRESEPSI MASYARAKAT DI KAWASAN PT JIEP (JAKARTA INDUSTRIAL ESTATE PULOGADUNG) DKI JAKARTA
Authors: Doan Otanti Agustina Doan Otanti Agustina , Abbas Hafid , Sucahyanto Sucahyanto 
Published: December 2022

Abstrak
Penelitian ini berjudul “STRATEGI PENANGGULANGAN BANJIR BERDASARKAN PRESEPSI MASYARAKAT DI KAWASAN PT JIEP (JAKARTA INDUSTRIAL ESTATE PULOGADUNG)DKI JAKARTA”.dalam hal ini bertujuan untuk 1) Mengetahui Strategi Penanggulangan sebelum Banjir di Kawasan PT JIEP (Jakarta Industrial Estate Pulogadung). 2) Mengetahui Strategi Penanggulangan saat Banjir di Kawasan PT JIEP (Jakarta Industrial Estate Pulogadung). 3) Mengetahui Strategi Penanggulangan sesudah Banjir di Kawasan PT JIEP (Jakarta Industrial Estate Pulogadung).

Penelitian menggunakan metode: Kegiatan survei dan kajian literatur dilaksanakan dengan mengumpulkan data dan informasi tentang banjir, hasil kajian, dan Selain itu, dilakukan wawancara singkat dan terarah dengan responden dari profesional PT JIEP (intermediaries) dan masyarakat (beneficiaries).

Hasil dalam penelitian saya, menunjukan bahwa strategi penanggulangan banjir berdasarkan persepsi masyarakat didaerah Kawasan PT Jakarta Insustrial Estate Pulogadung (JIEP) di Kecamatan Cakung kota administrasi Jakarta Timur berada pada kategori “sedang yang mana persiapan dan bantuan di dan normalisasi di bantu oleh pemerintah setempat.
Kata Kunci : Strategi penaggulangan, Banjir, Masyarakat kawasan PT JIEP.
High temperature sensitivity of monoterpene emissions from global vegetation
Authors: Bourtsoukidis Efstratios , Pozzer Andrea , Williams Jonathan , Makowski David , Penuelas Josep , Matthaios Vaseilios , Lazoglou Georgia , Yañez-Serrano Ana , Ciais Philippe , Lelieveld Jos , Vrekoussis Mihalis , Daskalakis Nikolaos , Sciare Jean 
Published: December 2022

Abstract
Terrestrial vegetation emits vast amounts of monoterpenes into the atmosphere, influencing ecological interactions and atmospheric chemistry. Global emissions, mostly driven by responses to abiotic stress, are simulated as a function of temperature with a fixed exponential relationship (β coefficient) across forest ecosystems and environmental conditions. We applied meta-analysis algorithms on all published monoterpene emission data and show that this relationship is more intricate and sensitive than previously thought. We find that co-occurring environmental stresses amplify the temperature sensitivity of the emissions that is primarily related to the specific plant functional type (PFT). On average, warmer ecosystems appear more sensitive, indicating the adjustment of plants in response to thermal stress. Implementing a PFT-dependent β in a biogenic emission model, coupled with a chemistry – climate model, demonstrated that atmospheric processes are exceptionally dependent on monoterpene emissions which are subject to amplified variations under rising temperatures.
Investigation of inhibiting factors of dysphagia rehabilitation in cardiovascular patients treated with invasive and non-invasive mechanical ventilation
Authors: Nakamura Tomoyuki , Kurosaki Shuhei , Baba Mikoto , Mizushima Takashi 
Published: December 2022

Abstract
Objectives
To clarify the factors inhibiting dysphagia rehabilitation in cardiovascular patients treated with invasive and non-invasive mechanical ventilation (MV).
Methods
The subjects were patients with dysphagia and cardiovascular disease treated with MV who were admitted to our hospital between April 2019-December 2021. Age, sex, walking ability, Geriatric Nutritional Risk Index (GNRI), primary heart disease, Charlson Comorbidity Index (CCI), invasive or non-invasive MV, Sequential Organ Failure Assessment (SOFA) at the start of MV, duration of MV, days from the withdrawal of MV to the start of rehabilitation, Functional Oral Intake Scale (FOIS) at the start of rehabilitation and discharge, length of hospital stay, pneumonia after the start of rehabilitation, and death during hospitalization were retrospectively surveyed.
Results
Ninety-six of the 105 patients survived, and 37 patients recovered from dysphagia. Twenty-two patients needed alternative nutrition at the start of rehabilitation, which was significantly associated with the duration of MV, length of hospital stay, and pneumonia after the start of rehabilitation. Death during hospitalization was significantly associated with lower GNRI scores, a history of chronic pulmonary disease, lower FOIS scores at the start of rehabilitation, and pneumonia developed during hospitalization. Dysphagia at discharge was significantly associated with older age, walking disability, lower GNRI scores, congestive heart failure, higher CCI scores, non-invasive MV, and higher SOFA scores.
Conclusions
The factors inhibiting dysphagia rehabilitation in cardiovascular patients treated with MV differed between the initial evaluation and outcomes and between vital and functional outcomes. Nutritional risk is a common risk factor for vital and functional outcomes.
Evaluation of Famacha© Method as a Selective Treatment Criteria to Aid to Conserve the Canindé Goats Breed
Authors: Goes Sarah Diogenes Mendonca de Mattos Brito , Ferreira Josiel , Silveira Robson Mateus Freitas , Bezerra Ana Carla Diógenes Suassuna , Façanha Débora Andréa Evangelista 
Published: December 2022

Abstract
This study evalueted the efficiency of the application of the Famacha© (F ©) system in goats of the Canindé breed. 161 goats were selected, which were examined and classified into 5 categories, F©1 to F©5. Blood samples were collected for complete blood count to get a health profile and hematocrit count (HTC), egg count per gram of feces (ECC) and stool culture to confirm the presence of H. contortus, in two periods of the year, dry and rainy. There were no significant differences between the HTC and F© data between the analyzed periods, and no animal was classified as truly anemic. Therefore, the study concluded that there is a contradictory relationship between the classification of anemia using the F© system, ECC and HTC values related to H. contortus infection, not suggesting the use of the F© method for Canindé goats and still proposing the elaboration of new HTC tracks associated with F© scores.