bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk‐based seismic design of base‐isolated structures with single surface friction sliders
Authors: O'Reilly Gerard J. , Yasumoto Hiroshi , Suzuki Yoshitaka , Calvi Gian Michele , Nakashima Masayoshi 
Published: May 2022

AbstractChoosing friction pendulum isolators to avoid problems with device displacement capacity or boundary wall collision is a critical part of the seismic design of base isolation systems. This paper developed a probabilistic method to quantify the risk of failure in single friction pendulum bearing (FPB) devices. This was done by calibrating a demand‐intensity model for FPBs from numerical analysis for several device property combinations. These properties encompassed the dynamic friction coefficient and effective radius of curvature—key parameters impacting these FPB devices’ seismic response. Through this demand‐intensity model, a closed‐form and relatively simple approach to quantify the mean annual frequency of exceeding a given device displacement threshold, or risk of failure, was proposed. By applying this simplified method to several case study structures and comparing it with a more extensive assessment involving multiple stripe analysis (MSA) using hazard‐consistent ground motions, the proposed simplified approach could provide very accurate estimates of displacement‐based failure risk in FPB devices under the assumption of no non‐linear behaviour in the superstructure. This proposed approach implies that structural engineers can now quickly assess the actual failure rates of different FPB device combinations used in practice to give a more uniform level of safety or reliability when designing and assessing FPB‐isolated systems. It is also arguably much simpler, direct and accurate than currently available code‐based approaches.
Performance improvement of co‐culture inoculated microbial fuel cell using fuzzy modelling and Harris hawks optimization
Authors: Rezk Hegazy , Sayed Enas Taha , Abdelkareem Mohammad Ali , Olabi A. G. 
Published: May 2022

SummaryMicrobial fuel cell (MFC) is a promising technology since two important processes: wastewater treatment and electrical energy, can be obtained simultaneously. The performance of the MFC (maximum power density (MPD) and COD removal) depends mainly on substrate concentration, pH time, and initial COD. Therefore, the main target of this work is to simultaneously increase the MPD and COD removal by determining the optimal controlling parameters. The proposed methodology integrates fuzzy modelling and Harris Hawks optimization (HHO). Firstly, based on the experimental data set, an accurate fuzzy model is created to simulate the performance of MFC in terms of four controlling parameters. To prove the superiority of fuzzy model, the results are compared with response surface methodology (RSM) in terms of RMSE and coefficient of determination (R2). Secondly, using HHO, the optimal values of substrate concentration, co‐culture composition, pH, and time are determined. These four controlling parameters are used as decision variables during the optimization process, whereas the objective function is the simultaneous maximization of the MPD and COD removal. The obtained results proved that the optimal substrate concentration, pH, time, and initial COD values are 58.2%, 7, 14.4 days, and 32 × 10−3 (mg/L) respectively. Under this condition, the integration between fuzzy and HHO, the overall performance of MFC has been improved by 10.37% and 19.13%, respectively, compared with the experimental and RSM.
Family‐reported barriers and predictors of short‐term attendance in a multidisciplinary intervention for managing childhood obesity: A psycho‐family‐system based randomised controlled trial (ENTREN‐F)
Authors: Rojo Marta , Lacruz Tatiana , Solano Santos , Gutiérrez Ana , Beltrán‐Garrayo Lucía , Veiga Oscar L. , Graell Montserrat , Sepúlveda Ana Rosa 
Published: May 2022

AbstractObjectiveThis study was aimed to examine patient enrolment in the pre‐intervention stage, family‐reported barriers, attendance rates and underlying predictors of short‐term attendance in a family‐system‐based randomised controlled trial for managing childhood obesity in children aged 8–12‐years‐old (ENTREN‐F).MethodPsychosocial and anthropometric measures were collected through primary health referral. The data were used for descriptive analyses of sample characteristics and linear regression analyses.ResultsLow enrolment rates and several family‐reported barriers were observed in the pre‐intervention stage. Logistical barriers were the most frequent family‐reported reason for attrition in the different stages of the study. Having a first face‐to‐face orientation session with the families and the use of motivational interviewing helped to improve adherence in the initial phases of the study. After 6 months of intervention, family based treatments (FBTs) under consideration achieve greater adherence compared with the standard intervention. Moreover, family involvement was a predictor of success for better treatment adherence rates. By contrast, participants who attended a brief standard intervention, mothers with primary education, greater body mass index, higher levels of depressive symptomatology and more critical comments towards their children, children with higher weight status and lower levels of self‐reported depressive symptoms at baseline attended interventions less frequently.ConclusionsIn future programmes a comprehensive screening of modifiable factors related to family and their setting characteristics is paramount prior to intervention, identifying key barriers related to drop‐out, especially in the case of less‐advantaged families.
Foredune height variations along the western coast of Taiwan Strait
Authors: He Yanyu , Cai Feng , Liu Jianhui , Qi Hongshuai , Li Bailiang , Zhao Shaohua , Liu Gen , Chen Xu 
Published: May 2022

AbstractKnowledge of the morphological characteristics of coastal foredunes, particularly crest height, is of crucial importance in evaluating coastal vulnerability to marine disasters. However, the factors driving variation in foredune height and the corresponding mechanisms remain poorly understood, especially for regional, large‐scale landscapes. In this contribution, an extensive foredune–beach topographic survey and comprehensive data collection, including regional wind regime, wave and tide climate, were conducted along the ~400 km‐long western coast of Taiwan Strait. The results show that the factor with the most significant effect on the spatial variation in foredune height is wave power, followed by aeolian drift potential (shore‐normal component), while beach width and grain size appear to have only marginal impacts for our study sites. Under a relatively high‐energy wave climate, significant volumes of sandy sediments can be delivered to the beach–dune system, and the beach state tends to be more dissipative, thus contributing to a higher/larger foredune. In particular, the in‐phase synchronization of sediment supply (contributed by wave processes) and transport potential (controlled by wind processes) can lead to the greatest potential for foredune growth. Finally, the source (river) to sink (coastal foredune) dispersal of sediments along this ~400 km‐long strait coastal regime is summarized.
Shrimp (Penaeus monodon) preservation by using chitosan and tea polyphenol coating combined with high‐pressure processing
Authors: Chen Lihang , Jiao Dexin , Zhou Bihe , Zhu Chen , Liu Jingsheng , Zhang Dali , Liu Huimin 
Published: May 2022

AbstractThe present work investigated the effects of high‐pressure processing (200 and 400 MPa, 5 min) combined with chitosan‐tea polyphenol (1.5% and 0.5% [w/v], respectively) coating to improve the quality and stability of shrimp (Penaeus monodon) during 28 days of storage. The chemical (pH, TVB‐N, TBARS), microbiological, textural, chromatic characteristics, protein oxidation, and endogenous enzyme activities of shrimps were regularly evaluated. Results showed that the combination treatment exerted a better intense antimicrobial effect, stabilized shrimp's freshness, and resulted in lower pH and TVB‐N than the control sample. Also, combined treated samples had better oxidative stability than a single treatment until the end of shelf life. Although combination treatment had no significant effect on endogenous proteases, the combined use of 400 MPa high‐pressure and chitosan‐tea polyphenol coating was most effective in inhibiting the bacteria and improved the hardness and chromatic characteristics of shrimp within the storage.
Physicochemical properties and sensory attributes of cookies prepared from sorghum and millet composite flour
Authors: Aljobair Moneera O. 
Published: May 2022

AbstractSorghum and millet are rich in nutrients and bioactive compounds. They can enhance nutrition and health. This study was aimed to develop sorghum–millet gluten‐free cookies from sorghum and millet composite flour. Cookies were made using 100% wheat WF100%, sorghum SF100% ,and millet MF100% flours and composite flours of 25% sorghum–75% millet (SF25%–MF75%), 50% sorghum−50% millet (SF50%–MF50%), and 75% sorghum–25% millet (SF75%–MF25%). The physicochemical, nutritional, bioactive, and sensory quality attributes of the developed cookies were evaluated.The results of flours displayed that the highest values of peak viscosity and final viscosity were observed in SF100%, breakdown and pasting temperature were observed in WF100%, setback viscosity in composite flour of SF25%–MF75%, and hardness and chewiness in WF 100%. Regarding cookies analysis results, the highest values of hardness were shown in WF100% and SF100% cookies, and the highest water activity was observed in the cookies of (SF25%–MF75% and SF50%–MF50%), and the (SF75%–MF25%) cookies had the best diameter and thickness. The lowest water‐holding capacity (WHC) and oil‐holding capacity (OHC) were found in (WF100%) cookies, while they were high in the cookies of SF and MF flours and their combinations (p ≤ .05). The cookies made using the composite flour of SF25%–MF75% appeared to have the uppermost values of moisture, protein, fat, total phenolic content (TPC), and antioxidant activity. They have the highest contents (p ≤ .05) of potassium, sodium, magnesium, and calcium. The scores of all sensory attributes of all cookie types were higher than the cutoff score (5). Overall, the incorporation of sorghum and millet flour in cookies formulation enhanced the physicochemical, nutritional, and bioactive properties without major effect on the sensory attributes of the product, which make it excellent nutritive and healthy sorghum–millet gluten‐free cookies.
Motivation and competition in health care
Authors: Scott Anthony , Sivey Peter 
Published: May 2022

AbstractNon‐pecuniary sources of motivation are a strong feature of the health care sector and the impact of competitive incentives on behavior may be lower where pecuniary motivation is low. This paper measures the marginal utility of income (MUY) of physicians from a stated‐choice experiment, and examines whether this measure influences the association between competition faced by physicians and the prices they charge. We find that physicians are more likely to exploit a lack of competition with higher prices if they have a high MUY.
Prognostic utility of key copy number alterations in T cell acute lymphoblastic leukemia
Authors: Kumari Sarita , Ali M. Shadab , Singh Jay , Arora Mohit , Verma Deepak , Pandey Avanish Kumar , Benjamin Mercilena , Bakhshi Sameer , Palanichamy Jayanth Kumar , Sharma Atul , Singh Inder , Tanwar Pranay , Singh Amar Ranjan , Pushpam Deepam , Qamar Imteyaz , Chopra Anita 
Published: May 2022

AbstractT‐cell acute lymphoblastic leukemia (T‐ALL) is a genetically heterogeneous disease, characterized by an abnormal transformation of T cells into highly proliferative leukemic lymphoblasts. Identification of common genetic alterations has provided promising opportunities for better risk stratification in T‐ALL. Current treatment in T‐ALL still poses the major challenge of integrating the knowledge of molecular alterations in the clinical setting. We utilized the Multiplex Ligation Dependent Probe Amplification (MLPA) method to determine the frequency of common copy number alterations (CNAs) in 128 newly diagnosed T‐ALL patients. We also studied the association of these CNAs with patient's clinical characteristics and survival. The highest frequency of deletion was observed in CDKN2A (59.38%), followed by CDKN2B (46.88%), LMO1 (37.5%), and MTAP (28.12%). PTPN2 (22.66%), PHF6 (14.06%), and MYB (14.06%) had the highest number of duplication events. A total of 89.06% patients exhibited CNAs. STIL::TAL1, NUP214::ABL1, and LMO2::RAG2 fusions were observed in 5.47%, 3.12%, and 0.78% of patients, respectively. CDKN2A, CDKN2B, and PTPN2 gene deletions were mainly observed in pediatric patients, while CNAs of NF1 and SUZ12 were observed more frequently in adults. In pediatric patients, alterations in CDKN2B, CASP8AP2, and AHI1 were associated with poor prognosis, while SUZ12 and NF1 CNAs were associated with favorable prognosis. In adult patients, ABL1 CNA emerged as an independent indicator of poor prognosis. The observed molecular heterogeneity in T‐ALL may provide the basis for variations observed in clinical response in T‐ALL and MLPA based CNA detection may help in risk stratification of these patients.
Risk factors for cardiovascular events and mortality in patients diagnosed with diffuse large B‐cell lymphoma and treated with anthracyclines
Authors: Diamond Akiva , Ayyappan Sabarish , Cao Shufen , Tashtish Nour , Boughan Kirsten , Cooper Brenda , Fu PingFu , Caimi Paolo F. 
Published: May 2022

AbstractThere is an increased risk of congestive heart failure (CHF) following anthracycline‐based chemotherapy in patients with Diffuse Large B‐cell lymphoma (DLBCL). Little is known about risk factors of CHF, other cardiovascular events (CVE), and CVE effect on outcomes. We conducted a retrospective review of 463 newly diagnosed DLBCL patients treated between 2002 and 2016 with anthracycline containing regimens. At a median follow up of 71.3 months, 10.4% patients developed new CHF, 4.97% had new atrial fibrillation and 3.2% had new coronary artery disease. Age over 65, advanced stage DLBCL and diabetes were associated with increased cumulative incidence of CVE. Patients with prior diabetes had decreased progression‐free survival and overall survival in comparison to non‐diabetics. Patients who had a CVE in the first year had significant worse OS then patients who did not have a CVE (Hazard Ratio 10.0, 95% CI, 7.24–13.88). A risk score incorporating age at DLBCL diagnosis, baseline lymphocyte count, disease stage and diabetes stratified into groups with low, intermediate and high risk for CVE, with 1‐year cumulative incidence of CVE of 5.3%, 7.9% and 13.4%. Diffuse large B‐cell lymphoma patients treated with anthracycline containing regimens have high incidence of CVE, which are not limited to CHF. Clinical variables at the time of diagnosis can identify the group of DLBCL patients at highest risk of CVE, for whom preventive interventions should be considered.
Barriers and challenges of using health information technology in home care: A systematic review
Authors: Galavi Zahra , Montazeri Mahdieh , Ahmadian Leila 
Published: May 2022

AbstractObjectiveDespite the benefits of applying Information technology (IT) in‐home care some challenges may affect the quality of the services. To deal with these challenges, it is required to identify them before providing such services. Therefore, the aim of this study is to systematically determine the challenges and barriers of using health IT in‐home care. Moreover, the possible solutions reported in the included studies were examined.Materials and MethodsWe performed a systematic search of the PubMed, Web of Science, and Embase databases for studies published between January 2010 and January 2020. For quality assessment of the included articles the Critical Appraisal Skills Programme and the Effective Public Health Practice Project checklists were used. The Supporting the Use of Research Evidence (Supporting the Use of Research Evidence (SURE)) framework was used to categorise the identified barriers and challenges.ResultsOf 1755 retrieved studies, 47 studies were included. The main barriers and challenges based on the SURE framework were categorised to Facilities (n = 35), Legislation or regulations (n = 19), Knowledge and skills (n = 18), Attitudes regarding programme acceptability, appropriateness and credibility (n = 16), Financial resources (n = 10), Motivation to change (n = 9), and External communication (n = 8). Studies mostly provided solutions regarding challenges related to the usability and functionality of the applied technology.ConclusionsThe results of this study can help policy‐makers and managers of health care organisations to be informed regarding the existing barriers, and implement safer and more effective home care systems. Awareness regarding barriers and potential challenges can help to provide optimal IT‐based interventions and facilitate providing home services.
Health policy response to mobility during the pandemic: Evaluating the effectiveness using location‐based services big data
Authors: Yuan Bocong , Zhao Hairong , Li Jiannan 
Published: May 2022

AbstractAs an emergent health policy response, the population mobility restriction policy was implemented to cope with the unprecedented pandemic that outbroke in early 2020, but its effectiveness showed vast disparities even within a single country. Using multisource data from Baidu mobility big data and the statistics of novel coronavirus disease in China, mobility restrictions (including restrictions on inflow‐mobility, outflow‐mobility, and intra‐city mobility) were examined. It was found that the mobility restriction had contained the development of pandemic, but such effect would gradually recede over time. Moreover, there existed region‐specific policy effectiveness. Specifically, outflow‐mobility restrictions were ineffective in reducing death cases in population influx areas, and restrictions on inflow‐mobility (or intra‐city mobility) were ineffective in reducing confirmed cases (or death cases) in population outflow areas. It was concluded that the mobility restriction policy can be effective in epidemic prevention and control in spatial‐temporal pattern. However, there was a remarkable disparity in policy effectiveness between different regions with different population mobility patterns.
Patient engagement in healthcare planning and evaluation: A call for social justice
Authors: Snow M. Elizabeth 
Published: May 2022

AbstractPatient engagement in healthcare planning and evaluation has been promoted as a way to improve healthcare's ability to meet patients' needs. However, populations experiencing oppression and discrimination, such as racism, colonialism, sexism, heterosexism, cisnormativity, ableism, classism, and poverty, are often underrepresented in patient engagement spaces. The context and structure of patient engagement processes may systematically exclude certain populations from participating in meaningful ways or from participating at all. By excluding certain populations from active, meaningful patient engagement, we risk planning and evaluating health services on the basis of the values, needs, and preferences of the dominant population. This, in turn, will further entrench health inequities and preclude the ability to surface ideas that challenge dominant conceptualisations of health and healthcare, thereby reinforcing the status quo rather than promoting healthcare transformation. Recognising that experiences of health, healthcare, and patient engagement processes are mediated through gender, race, ability, sexual orientation, and other dimensions of diversity, it is proposed that processes for engaging patients in healthcare planning and evaluation must by intersectional, attend to systemic and power relations, and truly put patients in the driver's seat of engagement processes. Health services planners and evaluators need to create more inclusive, accessible, and appropriate patient engagement experiences in order to focus on transforming healthcare towards a more socially just system.
Collaboration between health system decision makers and professional researchers to coproduce knowledge, a scoping review
Authors: Becerril‐Montekio Víctor , García‐Bello Luis Alberto , Torres‐Pereda Pilar , Alcalde‐Rabanal Jacqueline , Reveiz Ludovic , Langlois Etienne V. 
Published: May 2022

AbstractBackgroundRecent literature uses different terms and approaches to the collaboration between researchers and health system decision‐makers in the research process. In 2012, the World Health Organisation proposed to “Embed research within decision‐making processes”. Yet, important contributions use other terms and perspectives for the same issue. This scoping review aimed to identify these terms, approaches, their application and eventual influence on the utilization of evidence.MethodsWe searched papers published between January 2000 and February 2019 in English, Spanish, French and Portuguese in the databases of PubMed, Scielo, Google Scholar and EBSCOhost, thus accessing MedicLatina, MEDLINE Complete and eBook Collection. Our main inclusion criterion was the participation of health personnel in non‐clinical research activities. We considered three domains for in depth analysis: Definition, name and description of the participation of decision makers and health staff; Forms of collaboration and actual/effective participation of health staff in research; Eventual influence on the utilization of research results.ResultsWe identified 607 articles and selected 74 for full text analysis. Nineteen different terms are currently used in twelve countries to describe the participation of health decision‐makers and staff in research activities. Most publications refer to Integrated Knowledge Translation or Embedded Research, and were published in Canada and the United Kingdom. Forty‐five papers discuss the participation of health staff in research activities; 20 leading the whole process and 21 as collaborators.ConclusionsThe identification of the different terms and approaches to the close collaboration of health staff and decision‐makers with professional researchers is essential to promote its effective application and influence on the utilization of evidence. Yet, it is also necessary to insist in their co‐participation throughout the whole investigation process as a relevant way to improve research results uptake, strengthen health systems and advance towards universal health coverage.