bluuebunny/crossref_metadata_2025_split huggingface dataset:
Urban space, power and people through the optic of cemeteries in late medieval Cairo and Paris
Authors: John Caitlin 
Published: August 2022

AbstractThis article argues that a micro-historical and comparative analysis of urban burial spaces can provide fresh insight into cities. Two late medieval cemeteries are considered here: the Qarāfa in Cairo and Saints-Innocents in Paris. Despite the former being geographically peripheral and the latter central, both these relatively large cemeteries were integral to their respective urban spheres. Beyond the role of sultans and kings, collective shaping was key to the longue durée formation of both capitals’ cemeteries. They were also shaped by multiple urban communities of the living and the dead at the closer level and offer insight into these communities.
Morphological awareness and its role in early word reading in English monolinguals, Spanish–English, and Chinese–English simultaneous bilinguals
Authors: Marks Rebecca A. , Labotka Danielle , Sun Xin , Nickerson Nia , Zhang Kehui , Eggleston Rachel L. , Yu Chi-Lin , Uchikoshi Yuuko , Hoeft Fumiko , Kovelman Ioulia 
Published: August 2022

AbstractWords’ morphemic structure and their orthographic representations vary across languages. How do bilingual experiences with structurally distinct languages influence children's morphological processes for word reading? Focusing on English literacy in monolinguals and bilinguals (N = 350, ages 5–9), we first revealed unique contributions of derivational (friend-li-est) and compound (girl-friend) morphology to early word reading. We then examined mechanisms of bilingual transfer in matched samples of Spanish–English and Chinese–English dual first language learners. Results revealed a principled cross-linguistic interaction between language group (Spanish vs. Chinese bilinguals) and type of morphological awareness. Specifically, bilinguals’ proficiency with the type of morphology that was less characteristic of their home language explained greater variance in their English literacy. These findings showcase the powerful effects of bilingualism on word reading processes in children who have similar reading proficiency but different language experiences, thereby advancing theoretical perspectives on literacy across diverse learners.
Food purchase behaviour in a Finnish population: patterns, carbon footprints and expenditures
Authors: Meinilä Jelena , Hartikainen Hanna , Tuomisto Hanna L , Uusitalo Liisa , Vepsäläinen Henna , Saarinen Merja , Kinnunen Satu , Lehto Elviira , Saarijärvi Hannu , Katajajuuri Juha-Matti , Erkkola Maijaliisa , Nevalainen Jaakko , Fogelholm Mikael 
Published: August 2022

AbstractObjective:To identify food purchase patterns and to assess their carbon footprint and expenditure.Design:Cross-sectional.Setting:Purchase patterns were identified by factor analysis from the annual purchases of 3435 product groups. The associations between purchase patterns and the total purchases’ carbon footprints (based on life-cycle assessment) and expenditure were analysed using linear regression and adjusted for nutritional energy content of the purchases.Participants:Loyalty card holders (n 22 860) of the largest food retailer in Finland.Results:Eight patterns explained 55 % of the variation in food purchases. The Animal-based pattern made the greatest contribution to the annual carbon footprint, followed by the Easy-cooking, and Ready-to-eat patterns. High-energy, Traditional and Plant-based patterns made the smallest contribution to the carbon footprint of the purchases. Animal-based, Ready-to-eat, Plant-based and High-energy patterns made the greatest contribution, whereas the Traditional and Easy-cooking patterns made the smallest contribution to food expenditure. Carbon footprint per euros spent increased with stronger adherence to the Traditional, Animal-based and Easy-cooking patterns.Conclusions:The Animal-based, Ready-to-eat and High-energy patterns were associated with relatively high expenditure on food, suggesting no economic barrier to a potential shift towards a plant-based diet for consumers adherent to those patterns. Strong adherence to the Traditional pattern resulted in a low energy-adjusted carbon footprint but high carbon footprint per euro. This suggests a preference for cheap nutritional energy rather than environment-conscious purchase behaviour. Whether a shift towards a plant-based pattern would be affordable for those with more traditional and cheaper purchase patterns requires more research.
Charitable purposes and the shaping effects of money
Authors: Cowan Dave , Hardy Barbara 
Published: August 2022

AbstractWe address a curious omission from both the literature on the law of charity and socio-legal studies – the effect of apparently extraneous factors, such as politics and ideology, as well as the searching for money on the charitable purposes and identities of the public who are to benefit from the charity. This is a curious omission because even the law accepts that the idea of public benefit in charity law is a sociological concept, albeit one that has developed a technical meaning. We argue that approaching charitable purposes and public benefit as sociological concepts enables us to appreciate the tensions that those external factors produce as they re-shape those purposes and refashion the public who are to benefit. We refer to these factors under the rubric of the shaping effects of money. We use a case-study of the Canal and River Trust (CRT) to develop this argument. The trust was set up by the government as a charity to manage and control 2,000 miles of inland waterways in England and Wales. We draw on interviews with households who live on boats and ‘continuously cruise’ those boats on the canals to illustrate how their interests have been marginalised as the CRT has re-shaped itself as a well-being charity.
Objectified and Dehumanized: Does Objectification Impact Perceptions of Women Political Candidates?
Authors: Gothreau Claire M. , Alvarez Amanda Milena , Friesen Amanda 
Published: August 2022

AbstractObjectification and dehumanization are topics often discussed within the social psychology and feminist theory literature. Research on objectification has largely focused on the sexual objectification of women’s bodies, whereas the dehumanization literature has focused on dehumanization in the context of racial and ethnic groups. Extant political science research has only recently begun to engage with these concepts. In this manuscript, we build upon these literatures and apply these insights to questions relevant to politics. In particular, we argue that objectifying and dehumanizing portrayals of women impact how voters evaluate women politicians and how much they support gender parity in politics. Through a proposed experimental design, we test our hypothesis that the objectification of women as a group can decrease positive evaluations and likelihood of electoral support for women political candidates.
Strain Partitioning on the Western Haiyuan Fault System Revealed by the Adjacent 2016 Mw5.9 and 2022 Mw6.7 Menyuan Earthquakes
Authors: Luo Heng , Wang Teng 
Published: August 2022

AbstractThe 1,000 km‐long Haiyuan fault is the largest strike‐slip fault system in the northeastern Tibetan Plateau, accommodating part of the plateau's eastward extrusion. However, few large earthquakes have been instrumentally recorded, hindering our understanding of strain partitioning across the fault system. Here, we use synthetic aperture radar images to investigate fault geometries and slip distributions of the adjacent 2016 Mw5.9 and 2022 Mw6.7 Menyuan earthquakes that occurred 35 km apart along the western Haiyuan fault system. The purely strike and purely thrust slips of the 2022 and 2016 events indicate that strain was released separately on shallow steep fault and low‐angle fault at depth. We propose that such strain partitioning is controlled by the ratio between interseismic shear and normal velocities and the branching fault structure beneath the Lenglongling segment. Seismic hazard due to both focal mechanisms has to be considered along the western Haiyuan fault in northeastern Tibet.
Turbulent Dissipation in the Surface Mixed Layer of an Anticyclonic Mesoscale Eddy in the South China Sea
Authors: Dong Jihai , Fox‐Kemper Baylor , Jing Zhiyou , Yang Qingxuan , Tian Jiwei , Dong Changming 
Published: August 2022

AbstractClarifying contributions to the surface mixed layer (SML) dissipation from dynamic processes including winds, waves, buoyancy forcing and submesoscales is of significance for quantifying exchanges between the atmosphere and the ocean. Based on two observation sections across an anticyclonic eddy in the South China Sea, the contributions from different dynamic processes to the SML dissipation rate of turbulence are quantified. The potential vorticity indicates instability events including symmetric instability (SI), gravitational instability and centrifugal instability at the eddy. Despite of a dominant role of wind‐ and wave‐induced dissipation rates, SI is highlighted by a mean estimated depth‐integrated dissipation rate of 4.3 × 10−6 W m kg−1 with a maximum up to 3.2 × 10−5 W m kg−1. The SI dissipation is believed to play a role in the eddy kinetic energy budget by extracting energy from the vertical geostrophic shear at the eddy.
Development of the Sanya Incoherent Scatter Radar and Preliminary Results
Authors: Yue Xinan , Wan Weixing , Ning Baiqi , Jin Lin , Ding Feng , Zhao Biqiang , Zeng Lingqi , Ke Changhai , Deng Xiaohua , Wang Junyi , Hao Honglian , Zhang Ning , Luo Junhao , Wang Yonghui , Li Mingyuan , Cai Yihui , Liu Fanyu 
Published: August 2022

AbstractLed by the Institute of Geology and Geophysics, Chinese Academy of Sciences, we have built a brand‐new modular active digital phased array, with all solid‐state transmission and digital receiving incoherent scatter radar (ISR) in Sanya (18.3°N, 109.6°E), a station in low latitude China called Sanya ISR (SYISR) since 2015. The development of SYISR involved the indoor design and development of key components, an outdoor prototype test, and the production and debugging of the entire array. The unique features of SYISR include a single‐channel directly connected T/R unit and antenna, a radar array monitoring and calibration network, environmental adaptability design and open architecture. The entire radar has 4,096 channels and 5,930 modules in total. All the technical indices, mainly including a >2 MW peak power, a 43 dBi antenna gain and a <120 K noise temperature, either meet or are superior to the designed value through an independent evaluation. Waveforms of single pulse, linear frequency modulation, Barker code, long pulse and alternating code have been implemented to meet multiple purposes. Four observational modes for ionospheric experiments, including zenith stare, perpendicular to geomagnetic field, meridian scan, and all sky scan, have been developed. We have implemented time domain decoding, frequency domain decoding, and statistical inversion methods in calculating the autocorrelation function and power spectra in signal processing. The preliminary experimental results on ionospheric parameters, plasma lines, irregularities and hard targets are reasonable and encouraging, which greatly enhances our confidence in achieving our scientific goals in the future.
Stress Heterogeneity as a Driver of Aseismic Slip During the 2011 Prague, Oklahoma Aftershock Sequence
Authors: Okamoto Kristina K. , Savage Heather M. , Cochran Elizabeth S. , Keranen Katie M. 
Published: August 2022

AbstractThe interaction of aseismic and seismic slip before and after an earthquake is fundamental for both earthquake nucleation and postseismic stress relaxation. However, it can be difficult to determine where and when aseismic slip occurs within the seismogenic zone because geodetic techniques are limited to detecting moderate to large slip amplitudes or long duration small slip amplitudes. Here, we use repeating earthquakes (earthquakes that re‐rupture the same fault patch) as a proxy for aseismic slip during the 2011 Prague, Oklahoma earthquake sequence. We find that aseismic slip in the Prague earthquake sequence occurs both within the granitic basement and the overlying sedimentary rocks. The repeating earthquakes show that patches of aseismic slip are mostly located at fault intersections. These fault intersections hosted possible mainshock slip, abundant aftershocks, and afterslip. We estimate that ∼40% of the aftershocks are driven by afterslip. We interpret that aseismic slip occurs at fault intersections where stress heterogeneity creates patches of lower stress that are stable within a nonsteady state, rate‐state framework.
Surface Wave and Roller Dissipation Observed With Shore‐Based Doppler Marine Radar
Authors: Streßer Michael , Horstmann Jochen , Baschek Burkard 
Published: August 2022

AbstractSurface wave energy and dissipation are observed across the surf zone. Utilizing the concept of surface rollers, a new scaling is introduced to obtain the energy flux and dissipation related to rollers from Doppler velocities measured by a shore‐based X‐band marine radar. The dissipation of wave energy and hence the transformation of the incoming wave height (or energy) is derived using the coupled wave and roller energy balance equations. Results are compared to in‐situ wave measurements obtained from a wave rider buoy and two bottom mounted pressure wave gauges. A good performance in reproducing the significant wave height is found yielding an overall root‐mean‐square error of 0.22 m and a bias of −0.12 m. This is comparable to the skill of numerical wave models. In contrast to wave models, however, the radar observations of the wave and roller energy flux and dissipation neither require knowledge of the bathymetry nor the incident wave height. Along a 1.5 km long cross‐shore transect on a double‐barred, sandy beach in the southern North Sea, the highest dissipation rates are observed at the inner bar over a relatively short distance of less than 100 m. During the peak of a medium‐severe storm event with significant wave heights over 3 m, about 50% of the incident wave energy flux is dissipated at the outer bar.
Inorganic nanosheets facilitate humoral immunity against medical implant infections by modulating immune co-stimulatory pathways
Authors: Yang Chuang , Luo Yao , Shen Hao , Ge Min , Tang Jin , Wang Qiaojie , Lin Han , Shi Jianlin , Zhang Xianlong 
Published: August 2022

AbstractStrategies to manipulate immune cell co-inhibitory or co-activating signals have revolutionized immunotherapy. However, certain immunologically cold diseases, such as bacterial biofilm infections of medical implants are hard to target due to the complexity of the immune co-stimulatory pathways involved. Here we show that two-dimensional manganese chalcogenophosphates MnPSe3 (MPS) nanosheets modified with polyvinylpyrrolidone (PVP) are capable of triggering a strong anti-bacterial biofilm humoral immunity in a mouse model of surgical implant infection via modulating antigen presentation and costimulatory molecule expression in the infectious microenvironment (IME). Mechanistically, the PVP-modified MPS (MPS-PVP) damages the structure of the biofilm which results in antigen exposure by generating reactive oxidative species, while changing the balance of immune-inhibitory (IL4I1 and CD206) and co-activator signals (CD40, CD80 and CD69). This leads to amplified APC priming and antigen presentation, resulting in biofilm-specific humoral immune and memory responses. In our work, we demonstrate that pre-surgical neoadjuvant immunotherapy utilizing MPS-PVP successfully mitigates residual and recurrent infections following removal of the infected implants. This study thus offers an alternative to replace antibiotics against hard-to-treat biofilm infections.
Engineering an autonomous VH domain to modulate intracellular pathways and to interrogate the eIF4F complex
Authors: Frosi Yuri , Lin Yen-Chu , Shimin Jiang , Ramlan Siti Radhiah , Hew Kelly , Engman Alf Henrik , Pillai Anil , Yeung Kit , Cheng Yue Xiang , Cornvik Tobias , Nordlund Par , Goh Megan , Lama Dilraj , Gates Zachary P. , Verma Chandra S. , Thean Dawn , Lane David P. , Asial Ignacio , Brown Christopher J. 
Published: August 2022

AbstractAn attractive approach to target intracellular macromolecular interfaces and to model putative drug interactions is to design small high-affinity proteins. Variable domains of the immunoglobulin heavy chain (VH domains) are ideal miniproteins, but their development has been restricted by poor intracellular stability and expression. Here we show that an autonomous and disufhide-free VH domain is suitable for intracellular studies and use it to construct a high-diversity phage display library. Using this library and affinity maturation techniques we identify VH domains with picomolar affinity against eIF4E, a protein commonly hyper-activated in cancer. We demonstrate that these molecules interact with eIF4E at the eIF4G binding site via a distinct structural pose. Intracellular overexpression of these miniproteins reduce cellular proliferation and expression of malignancy-related proteins in cancer cell lines. The linkage of high-diversity in vitro libraries with an intracellularly expressible miniprotein scaffold will facilitate the discovery of VH domains suitable for intracellular applications.
Introducing Brønsted acid sites to accelerate the bridging-oxygen-assisted deprotonation in acidic water oxidation
Authors: Wen Yunzhou , Liu Cheng , Huang Rui , Zhang Hui , Li Xiaobao , García de Arquer F. Pelayo , Liu Zhi , Li Youyong , Zhang Bo 
Published: August 2022

AbstractOxygen evolution reaction (OER) consists of four sequential proton-coupled electron transfer steps, which suffer from sluggish kinetics even on state-of-the-art ruthenium dioxide (RuO2) catalysts. Understanding and controlling the proton transfer process could be an effective strategy to improve OER performances. Herein, we present a strategy to accelerate the deprotonation of OER intermediates by introducing strong Brønsted acid sites (e.g. tungsten oxides, WOx) into the RuO2. The Ru-W binary oxide is reported as a stable and active iridium-free acidic OER catalyst that exhibits a low overpotential (235 mV at 10 mA cm−2) and low degradation rate (0.014 mV h−1) over a 550-hour stability test. Electrochemical studies, in-situ near-ambient pressure X-ray photoelectron spectroscopy and density functional theory show that the W-O-Ru Brønsted acid sites are instrumental to facilitate proton transfer from the oxo-intermediate to the neighboring bridging oxygen sites, thus accelerating bridging-oxygen-assisted deprotonation OER steps in acidic electrolytes. The universality of the strategy is demonstrated for other Ru-M binary metal oxides (M = Cr, Mo, Nb, Ta, and Ti).
Tribological, oxidation and thermal conductivity studies of microwave synthesised molybdenum disulfide (MoS2) nanoparticles as nano-additives in diesel based engine oil
Authors: Nagarajan Thachnatharen , Khalid Mohammad , Sridewi Nanthini , Jagadish Priyanka , Shahabuddin Syed , Muthoosamy Kasturi , Walvekar Rashmi 
Published: August 2022

AbstractLubrication has become essential in enhancing engine efficiency in the era of rapid globalising. The tribological, oxidation and thermal conductivity properties of an engine oil play a vital role in improving the quality of a vehicle’s engine life. In this research, molybdenum disulfide (MoS2) nanoparticle was synthesised via a microwave hydrothermal reactor. Later, the nanoparticles were dispersed in SAE 20W50 diesel engine oil to formulate the nanolubricant. The results show that nanolubricant with 0.01 wt% MoS2 concentration showed the coefficient of friction, average wear scar diameter decreased by 19.24% and 19.52%, respectively, compared to the base oil. Furthermore, the nanolubricant with 0.01 wt% concentration of MoS2 nanoparticle showed an enhancement of 61.15% in oxidation induction time in comparison to the base oil. Furthermore, MoS2 addition within the base oil demonstrates a ~ 10% improvement in thermal conductivity compared to the base oil.
Spatiotemporal mapping of malaria incidence in Sudan using routine surveillance data
Authors: Elagali Ahmed , Ahmed Ayman , Makki Nada , Ismail Hassan , Ajak Mark , Alene Kefyalew Addis , Weiss Daniel J. , Mohammed Abdalla Ahmed , Abubakr Mustafa , Cameron Ewan , Gething Peter , Elagali Asmaa 
Published: August 2022

AbstractMalaria is a serious threat to global health, with over $$95\%$$

95
%

of the cases reported in 2020 by the World Health Organization in African countries, including Sudan. Sudan is a low-income country with a limited healthcare system and a substantial burden of malaria. The epidemiology of malaria in Sudan is rapidly changing due to factors including the rapidly developing resistance to drugs and insecticides among the parasites and vectors, respectively; the growing population living in humanitarian settings due to political instability; and the recent emergence of Anopheles stephensi in the country. These factors contribute to changes in the distribution of the parasites species as well as malaria vectors in Sudan, and the shifting patterns of malaria epidemiology underscore the need for investment in improved situational awareness, early preparedness, and a national prevention and control strategy that is updated, evidence based, and proactive. A key component of this strategy is accurate, high-resolution endemicity maps of species-specific malaria. Here, we present a spatiotemporal Bayesian model, developed in collaboration with the Sudanese Ministry of Health, that predicts a fine-scale (1 km $$\times $$
×
1 km) clinical incidence and seasonality profiles for Plasmodium falciparum and Plasmodium vivax across the country. We use monthly malaria case counts for both species collected via routine surveillance between January 2017 and December 2019, as well as a suite of high-resolution environmental covariates to inform our predictions. These epidemiological maps provide a useful resource for strategic planning and cost-effective implementation of malaria interventions, thus informing policymakers in Sudan to achieve success in malaria control and elimination.
Continuous activation of the IL-17F driven inflammatory pathway in acute and chronic digital dermatitis lesions in dairy cattle
Authors: Vermeersch Anne-Sofie , Geldhof Peter , Ducatelle Richard , Gansemans Yannick , Van Nieuwerburgh Filip , Deforce Dieter , Opsomer Geert 
Published: August 2022

AbstractObjectives of the present study were to get a deeper insight into the course of the inflammatory pathways of digital dermatitis lesions in dairy cattle by investigating the gene expression patterns throughout the different clinical stages (M0 to M4.1) of the disease. Normal skin samples (M0) were used as a reference for comparing the gene expression levels in the other M-stages through RNA Seq-technology. Principal component analysis revealed a distinct gene expression pattern associated with digital dermatitis lesions in comparison to healthy skin with a further clustering of the acute M1, M2 and M4.1 stages versus the chronic M3 and M4 stages. The majority of the up-and downregulated genes in the acute and chronic stages can be placed into a common ‘core’ set of genes involved in inflammation, such as A2ML1, PI3, CCL11 and elafin-like protein, whereas the most downregulated genes included keratins and anti-inflammatory molecules such as SCGB1D and MGC151921. Pathway analysis indicated the activation of the pro-inflammatory IL-17 signaling pathway in all the M stages through the upregulation of IL-17F. These results indicate that digital dermatitis is associated with an excessive inflammatory immune response concomitant with a disrupted skin barrier and impaired wound repair mechanism. Importantly, despite their macroscopically healed appearance, a significant inflammatory response (Padj < 0.05) was still measurable in the M3 and M4 lesions, potentially explaining the frequent re-activation of such lesions.