bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Association between Health Behavior and Health Promotion Needs of Village Health Volunteers in Thailand
Authors: Taejarernwiriyakul Ormjai , Keatrungarun Chorlada , Yuenton Thanachapon , Jantosee Panita , Sommatas Apisara 
Published: May 2022

Background:
Village health volunteers (VHV) are health community leaders responsible for improving the health and quality of life of the people of a community.For example, screening for COVID-19 in the community.

Materials and Methods:
The cross-sectional survey research aimed to study the association between health behavior and health promotion needs of VHV in Ongkharak District, Nakhon Nayok Province, Thailand. The subjects consisted of 270 VHV in Ongkharak District. The research instrument was a questionnaire with Cronbach’s alpha coefficient at 0.81. Data were analyzed by descriptive statistics, Chi-square, and Pearson's Product Moment Correlation Coefficient.

Results:
The health behaviors of VHV (M = 1.9 SD = 0.3) were at a moderate level. The health promotion needs (M = 2.9 SD = 0.3) were at high level. Health behavior was positively related to the health promotion needs of the VHV significantly (r = 0.0318, p – value = 0.000).

Conclusion:
The findings of this study may be used to provide insights to agencies involved in health promotion in order to determine how to best assist VHV in receiving health promotion and suitable services that conform to their requirements.
Transfer Validity of Pediatric Supracondylar Humeral Fracture Pin Placement Practice on In-Theater Performance by Orthopedic Trainees Using an Augmented Reality Simulator: Protocol for a Pilot Interventional Cohort Study With a Retrospective Comparator Cohort
Authors: Guo Joyce , Blyth Phil , Clifford Kari , Hooper Nikki , Crawford Haemish 
Published: May 2022

Background
Supracondylar humeral fractures (SCHF) are a common cause of orthopedic morbidity in pediatric populations across the world. The treatment of this fracture is likely one of the first procedures involving x-ray–guided wire insertion that trainee orthopedic surgeons will encounter in their career. Traditional surgical training methods of “see one, do one, teach one” are reliant on the presence of real-world cases and must be conducted within an operative environment. We have developed an augmented reality simulator that allows trainees to practice this procedure in a radiation-free environment at no extra risk to patients.

Objective
This study aims to examine whether training on a simulator in addition to traditional surgical training improves the in-theater performance of trainees.

Methods
This multicenter, interventional cohort study will involve orthopedic trainees from New Zealand in their first year of advanced training between 2019 and 2023. Advanced trainees with no simulator exposure who were in their first year in 2019-2021 will form the comparator cohort, while those in the years 2022-2023 will receive additional regular simulator training as the intervention cohort. The comparator cohort’s performance in pediatric SCHF surgery will be retrospectively audited using routinely collected operative outcomes and parameters over a 6-month period. Data on the performance of the intervention cohorts will be collected in the same way over a comparable period. The data collected for both groups will be used to determine whether additional training with an augmented reality training shows improved real-world surgical outcomes compared to traditional surgical training.

Results
As of February 2022, a total of 8 retrospective comparator trainees have been recruited by email. The study is financially supported through an external grant from the Wishbone Orthopaedic Research Foundation of New Zealand (September 2021) and an internal research grant from the University of Otago (July 2021).

Conclusions
This protocol has been approved by the University of Otago Health Ethics committee (reference HD21/087), and the study is due for completion in 2024. This protocol may assist other researchers conducting similar studies in the field.

Trial Registration
Australian New Zealand Clinical Trials Registry ACTRN12623000816651; https://tinyurl.com/mtdkecwb

International Registered Report Identifier (IRRID)
DERR1-10.2196/38282
Use of Bacopa monnieri in the Treatment of Dementia Due to Alzheimer Disease: Systematic Review of Randomized Controlled Trials
Authors: Basheer Aneesh , Agarwal Ayush , Mishra Biswamohan , Gupta Anu , Padma Srivastava Madakasira Vasantha , Kirubakaran Richard , Vishnu Venugopalan 
Published: May 2022

Background
Bacopa monnieri, a herb that has been used for many centuries in India, has shown neuroprotective effects in animal and in vitro studies; human studies on patients with Alzheimer disease have been inconclusive.

Objective
The primary objective of this review was to determine the clinical efficacy and safety of B. monnieri in persons with mild, moderate, or severe dementia, or mild cognitive impairment, due to Alzheimer disease.

Methods
We searched PubMed, Embase, Cochrane Library, clinical trial registries (World Health Organization, Australia-New Zealand, United States, and South Africa), the metaRegister of Controlled Trials, and CINAHL. We intended to include all randomized and quasi-randomized controlled trials that compared B. monnieri, its extract or active ingredients (at any dosage), with a placebo or a cholinesterase inhibitor among adults with dementia due to Alzheimer disease and in those with mild cognitive impairment due to Alzheimer disease.

Results
Our comprehensive search yielded 5 eligible studies. A total of 3 studies used B. monnieri in combination with herbal extracts while the remaining 2 used B. monnieri extracts only. Two studies compared B. monnieri with donepezil while the others used a placebo as the control. There was considerable variation in the B. monnieri dose used (ranging between 125 mg to 500 mg twice daily) and heterogeneity in treatment duration, follow-up, and outcomes. The major outcomes were Mini-Mental State Examination scores reported in 3 trials, Cognitive subscale scores of the Alzheimer’s Disease Assessment Scale in 1 study, and a battery of cognitive tests in 2 studies. Using the Cochrane risk-of-bias tool, overall, we judged all 5 studies to be at high risk of bias. While all studies reported a statistically significant difference between B. monnieri and the comparator in at least one outcome, we rated the overall quality of evidence for the Alzheimer’s Disease Assessment Scale-Cognitive Subscale, Postgraduate Institute Memory Scale, Mini-Mental State Examination, and Wechsler Memory Scale to be very low due to downgrading by 2 levels for high risk of bias and 1 more level for impreciseness due to small sample sizes and wide CIs.

Conclusions
There was no difference between B. monnieri and the placebo or donepezil in the treatment of Alzheimer disease based on very low certainty evidence. No major safety issues were reported in the included trials. Future randomized controlled trials should aim to recruit more participants and report clinically meaningful outcomes.

Trial Registration
PROSPERO CRD42020169421; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=169421
Macrophage phenotype after human refluxate exposure, esophageal dysmotility and their correlation with gastroesophageal reflux disease
Authors: Paraskevova A. V. , Trukhmanov A. S. , Storonova O. A. , Lyamina S. V. , Kalish S. V. , Pirogov S. S. , Ponomarev A. B. , Rumyantseva D. E. , Malyshev I. Yu. , Maev I. V. , Ivashkin V. T. 
Published: May 2022

Aim of the study. To investigate the esophageal dysmotility, changes in the esophageal mucosa and the immune response depending on the type of refluxate in gastroesophageal reflux disease (GERD) patients.Material and methods. 68 patients with GERD were recruited: 28 (14 men; mean age, 45.74 ± 2.23 years) nonerosive reflux disease (NERD), 22 (15 men; mean age, 45.0 ± 3.24 years) erosive reflux disease (EE), 18 (13 men; mean age, 47.22 ± 2.95) Barrett’s Esophagus (BE). GERD patients underwent esophageal high-resolution manometry (HRM) with a 22-channel water-perfused catheter and Solar GI system (Medical Measurements Systems, Enschede, the Netherlands), 24-hour impedance and pH monitoring using the Ohmega Ambulatory Impedance pH Recorder (Medical Measurements Systems). We analyzed receptor characteristics of monocyte-derived macrophages in all groups of patients.Results. On HRM examination, we showed that DCI (distal contractile integral) in NERD patients was higher than in EE (p = 0.088) and BE (p = 0.076), also LES RP (lower esophageal sphincter resting pressure) in NERD patients was higher than in EE (p = 0.039) and BE (p = 0.012). The analysis of reflux characteristics showed that the total reflux time with pH < 4 for BE patients was longer than that for NERD and EE patients. An analysis of receptor characteristics of monocyte-derived macrophages showed the prevalence of CD25 and CD80 expression in all groups of patients.Conclusion. An analysis of the phenotype of macrophages derived from blood monocytes of GERD patients revealed a prevalence of М1 macrophages that was typical for the Th1 type of immune response. The degree of esophageal dysmotility was correlated with GERD severity and type.
Successful living donor liver transplantation of the left lateral sector with simultaneous atypical resection of the S2 for focal nodular hyperplasia
Authors: Rzayev R. T. , Kamalov Yu. R. , Kryzhanovskaya E. Yu. , Tatarkina M. A. , Kovaleva A. L. 
Published: May 2022

The purpose of presenting a clinical observation. Description of a clinical observation of a successful atypical resection of focal nodular hyperplasia of the segment II of the liver to a relative donor, followed by transplantation of the left lateral sector of the liver to a one-year-old child with cirrhosis of the liver in the outcome of biliary atresia.General provisions. Patient Z., 29 years old, was examined as donor for related liver sector transplantation. The oval structure with fairly smooth contours, hyperechoic in the central parts and hypoechoic in the periphery, was found in the segment II during the ultrasound examination; assessment of blood flow was difficult due to acoustic interference. According to computed tomography, it was a weak hypervascular formation with fuzzy contours, accumulating contrast medium unevenly in the arterial phase, with visualization of a small hypodense area around, also accumulating contrast medium in the venous phase. According to magnetic resonance imaging, there is a zone of increased MR signal, with contrast enhancement uniformly accumulating contrast in the arterial phase. It was assumed that the patient had focal nodular liver hyperplasia. The patient underwent surgery, during which the left lateral sector of the liver was removed and a single-step atypical resection of the segment II was performed. Histological examination of the surgical material confirmed the presence of FNH. After excision and suturing of vascular structures in conditions of continued blood circulation, the left lateral sector was removed from the wound and implanted into the recipient in an orthotopic position. The postoperative period passed without complications. The donor and recipient were discharged from the hospital in a satisfactory condition on the planned date.Conclusion. This observation demonstrates the possibility of using a liver fragment as a transplant after resection of focal nodular hyperplasia.
New evidence of central nervous system damage in diabetes mellitus: impairment of fine visual discrimination
Authors: Chen He , Wang Menghan , Xia Lin , Dong Jiong , Xu Guangwei , Wang Ziyi , Feng Lixia , Zhou Yifeng 
Published: May 2022

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<p>Diabetes can damage both the peripheral sensory organs, causing retinopathy, as well as the central visual system, leading to contrast sensitivity and impaired color vision in patients without retinopathy. Orientation discrimination is important for shape recognition by the visual system. Our psychophysical findings in this study show diminished orientation discrimination in diabetic patients without retinopathy. To reveal the underlying mechanism, we established a diabetic mouse model and recorded in vivo electrophysiological data in the dorsal lateral geniculate nucleus (dLGN) and primary visual cortex (V1). Reduced orientation selectivity was observed in both individual and populations of neurons in V1 and dLGN, which increased in severity with disease duration. This diabetes-associated neuronal dysfunction appeared earlier in the V1 than dLGN. Additionally, neuronal activity and signal-to-noise ratio is reduced in V1 neurons of diabetic mice, leading to a decreased capacity for information processing by V1 neurons. Notably, the V1 in diabetic mice exhibits reduced excitatory neuronal activity and lower levels of phosphorylated mammalian target of rapamycin (mTOR). Our findings show that altered responses of both populations and single V1 neurons may impair fine vision, thus expanding our understanding of the underlying causes of diabetes-related impairment of the central nervous system.</p>
Interaction design of financial insurance products under the Era of AIoT
Authors: An Wa , Wang Shaobin , Chen Ye , Wu Qiang , Wu Changyu , Wang Kai , Wang Shiqi , Chen Huachun , Chen Zhihao 
Published: May 2022

Abstract
This study aims to explore how the insurance business can combine artificial intelligence (AI), huge data technology and good design under the ecological background of AIoT to improve the efficiency of double-entry in the insurance business and improve the user experience. It is accomplished through observation, user interview and other methods to explore user needs and distress points, comprehensive use of image and video analysis, face recognition, behaviour detection and other AI technologies. aiCore intelligent dual-recording system is proposed, which integrated mobile terminal dual-recording application and backstage quality control system. The proposed system realised the design optimisation of the whole process of intelligent dual-recording scenario combining the three functions ‘front-end intelligent dual-recording, in-process real-time quality control and post-AI quality control.’ Using in-process detection, post-review and manual final audit, the aiCore intelligent dual-recording system has significantly improved the efficiency of dual-recording, quality inspection pass rate and user experience satisfaction.
Exploration on the collaborative relationship between government, industry, and university from the perspective of collaborative innovation
Authors: Zhu Zhaoge , Cui Shengnan , Wang Yanqiu , Zhu Zhiwei 
Published: May 2022

Abstract
The idea that reform drives innovation and entrepreneurship, and innovation and entrepreneurship drive development, has gradually become the main theme of the new era of Chinese society. As the ‘cradle’ of knowledge and technology innovation and the training and output of innovative talents, colleges and universities are the inevitable choices of the times to conform to the social trend and change to the development model of ‘entrepreneurial universities’. This article takes the reform of the development model of universities in Heilongjiang Province as the research object, and it qualitatively explores the status quo of the reform and development of universities in Heilongjiang Province to entrepreneurial universities, with the aid of the Loet Leydesdorff triple helix algorithm, based on the Web of Science database and national intellectual property ‘patent search and analysis’. The platform conducts data mining, conducts quantitative measurement research on the collaboration relationship between government, industry, university and research, and focuses on Heilongjiang Province for horizontal and vertical empirical analyses. The study proposes suggestions for improvement from the three dimensions of condensing the collaborative awareness of innovation subjects, reforming the development model of scientific research institutions, and improving the efficiency of the absorption and transformation of enterprise scientific and technological achievements. It has certain practical guidance for strengthening the mutual information coordination and structural stability of the government, industry, university and research under the collaborative innovation ecosystem.
Effect of novel grain refiner and Ni alloying additions on microstructure and mechanical properties of Al-Si9.8-Cu3.4 HPDC castings – optimization using Multi Criteria Decision making approach
Authors: Apparao K. Ch , Bannaravuri Praveen Kumar , Pulisheru Kumar Swamy , Francis E. D. , Alfred Sunny Kalakanda , Babu Rao Gadudasu , Daniel P Freedon , Birru Anil Kumar 
Published: May 2022

Abstract
Studies dealing with process improvement of aluminum alloys and their grain structure refinement are the current area of interest in casting companies and foundries, the aim being to enhance the properties of the base metal. In this study, the microstructural and mechanical properties of commercial Al-Si9.8-Cu3.4 alloy die castings influenced by different additions of Al-3.5FeNb-1.5C master alloy (viz. 0 wt.%, 0.1 wt.%, and 1.0 wt.%) as a new grain refiner and Al-6Ni master alloy (viz. 0 wt.%, 0.5 wt.%, and 5.0 wt.%) as an alloying element have been investigated. A multi-criteria decision-making approach for the improvement of the die casting process was performed using grey relational analysis (GRA) and TOPSIS analytical techniques. It was observed that the primary aluminum α-grains were significantly refined, particularly at the lower addition level 0.1 wt.% of Al-3.5FeNb-1.5C, and conversely, poor grain refining efficiency was observed at a higher addition level 1.0 wt.% of Al-3.5FeNb-1.5C. Due to the refinement by Al-3.5FeNb-1.5C grain refiner and the effect of Ni alloying element additions, the ultimate tensile strength (UTS) and hardness (Brinell and micro) of the Al-Si9.8-Cu3.4 alloy are improved, particularly at 0.1 wt.% of Al-3.5FeNb-1.5C and 0.5 wt.% of Al-6Ni master alloys. Quantitatively, UTS, Brinell hardness, and microhardness values have been increased by 12.3%, 7.0%, and 20%, respectively.
Preferences of the 1st year medical students on various teaching methods and their feedback on curriculum quality in Biochemistry
Authors: Maheswari K. , Goswami Binita , Singh Kamna , Jamatia Elvia , Kaushik Smita 
Published: May 2022

Objectives:
Medical teaching requires introduction of new teaching methods to cover the vast curriculum in stipulated time. Apart from conventional teaching, newer teaching learning methods such as video clippings, problem-based learning (PBL), seminars, early exposure to patients, hospital laboratory visits, debates, quiz, and group discussions need to be introduced. The study was conducted to gauge the student’s perception regarding the teaching methodology adopted by the department of Biochemistry for the 1st year MBBS students. Along with this, feedback was also taken to assess the student’s views on their present assessment system as well as on various aspects of the current MBBS curriculum and on their relationship with their teachers.

Materials and Methods:
This was an observational study conducted in the department of Biochemistry and the data were collected using a pre-designed questionnaire from the 1st year MBBS students after completion of the 1st year Biochemistry course.

Results:
The questionnaire evaluated different teaching methods for various topics in Biochemistry. Among 243 students included in the study, didactic lecture was preferred by 80 students for endocrinology and 82 for cancer biology topics. Debate was preferred for the topic of nutrition (n = 82). Ninety-one students chose case-based learning for learning clinical Biochemistry. Video-based learning was preferred for the topic of molecular biology by 80 students.

Conclusion:
Students prefer different combinations of teaching learning method for better understanding of the subject. Early clinical exposure and effective tutorial sessions will definitely improve the learning gain among pre-clinical students.
Surgical management of embolized jugular foramen paragangliomas without facial nerve transposition: Experience of a public tertiary hospital in Brazil
Authors: Colli Benedicto Oscar , Junior Carlos Gilberto Carlotti , de Oliveira Ricardo Santos , Gondim Guilherme Gozzoli Podolski , Abud Daniel Giansanti , Massuda Eduardo Tanaka , de Melo Filho Francisco Veríssimo , Tanaka Koji 
Published: May 2022

Background:
Jugular foramen paragangliomas (JFP) treatment represents a challenge for surgeons due to its close relationship with facial nerve (FN), lower cranial nerves (LCN), and internal carotid artery. Due to its hypervascularization, preoperative tumor embolization has been indicated.

Methods:
Retrospective analysis of the clinical evolution of 26 patients with JFP class C/D previously embolized treated through infratemporal/cervical access without FN transposition.

Results:
Total and subtotal resections were 50% each, regrowth/recurrence were 25%, and 23%, respectively, and mortality was 3.9%. Postoperatively, 68.4% of patients had FN House and Brackmann (HB) Grades I/II. New FN deficits were 15.4% post embolization and 30.7% postoperatively. Previous FN deficits worsened in 46.1%. Tumor involved the FN in 30.8% and in 62.5% of them these nerves were resected and grafted (60% of them had HB III). Lateral fall, ear murmur, and vertigo improved in all patients. Tinnitus improved in 77.8% and one patient developed tinnitus after surgery. Hearing loss did not improve, eight partial hearing loss remained unchanged and four worsened. New postoperative LCN deficits were 64.3%. Postoperative KPS between 80 and 100 dropped 8.3%. Two patients with secretory paragangliomas with arterial hypertension difficult to control had better postoperative blood pressure control.

Conclusion:
Although still with significant morbidity due to FN and LCN injuries, the treatment of patients with JFP Fisch C/D has good long-term results. Surgical techniques without FN transposition have less intraoperative nerve damage, lower rates of total resection, and higher recurrence. Preoperative embolization of JFP reduces the intraoperative blood loss but can cause FN deficit.
SASTRA BANDING NOVEL KEMARAU KARYA A.A NAVIS DENGAN NOVEL THE DRY KARYA JANE HARPER
Authors: Nitami Adya , Hartati Dian 
Published: May 2022

The purpose of this study is to compare literary works in the novel Kemarau by A.A Navis and the novel The dry by Jane Harper. The method used in this research is descriptive qualitative research method. In the management of the data generated using the analysis of the theory of sociology of literature. This study uses a comparison table contained in the novel Kemarau by A.A Navis and the novel The Dry by Jane Harper. The results of comparison of social values contained in the two novels, the novel Kemarau by A.A Navis explains social values and the values about life contained in the novel Kemarau by A.A Navis. Meanwhile, Jane Harper's novel The Dry is quite the opposite, but there are still moral values inserted. Through this research, it is hoped that it can increase reader's interest in literary works, and can increase the interest of researchers in comparative literary research.Keywords: Novel, Comparative Literature, Drought, Fiction.