bluuebunny/crossref_metadata_2025_split huggingface dataset:
An LBS and agent-based simulator for Covid-19 research
Authors: Du Hang , Yuan Zhenming , Wu Yingfei , Yu Kai , Sun Xiaoyan 
Published: December 2022

AbstractThe mobility data of citizens provide important information on the epidemic spread including Covid-19. However, the privacy versus security dilemma hinders the utilization of such data. This paper proposed a method to generate pseudo mobility data on a per-agent basis, utilizing the actual geographical environment data provided by LBS to generate the agent-specific mobility trajectories and export them as GPS-like data. Demographic characteristics such as behavior patterns, gender, age, vaccination, and mask-wearing status are also assigned to the agents. A web-based data generator was implemented, enabling users to make detailed settings to meet different research needs. The simulated data indicated the usability of the proposed methods.
Pan-cancer analysis of the prognostic and immunological role of PAQR4
Authors: Wang Kaibin , Meng Jinhuan , Wang Xudong , Yan Mo , Liu Shuaibing , Yang Shaobo , Xu Shengxian , Liu Dongze , Li Changying , Yang Kuo 
Published: December 2022

AbstractProgestin and adipoQ receptor family member 4 (PAQR4) is a protein-coding gene. Recent studies have shown that PAQR4 is related to the development of multiple cancers. However, there is no systematic pan-cancer analysis of this gene. In this study, the expression of PAQR4, correlations with clinical prognosis, immune situation, and its potential molecular functions and mechanisms in pan-cancer were explored by bioinformatics analysis. The Cancer Genome Atlas was applied to investigate the relations between PAQR4 and clinical features, prognostic effects, and tumor immune microenvironment. R software was used to perform statistical analysis and figure creation. The expression of PAQR4 in BLCA and KIRC was validated by qRT-PCR and immunohistochemistry, and its function was explored by cellular experiments. Bioinformatics analysis revealed that PAQR4 was up-regulated in multiple cancers and related to poor prognosis. The high expression of PAQR4 was closely associated with high tumor stage, immune cell infiltration, tumor mutation burden, and microsatellite instability in different cancer types. In addition, the high expression of PAQR4 also indicated involvement in the immune regulatory pathways. The involvement of PAQR4 in the immune regulation of different tumors was confirmed by GSEA enrichment analysis. Moreover, PAQR4 was highly expressed in bladder cancer and renal clear cell carcinoma tissues and cell lines. Cell proliferation, migration, and invasion of bladder cancer and renal clear cell carcinoma cell lines were significantly decreased after the knockdown of PAQR4. This study elucidated the role of PAQR4 in carcinogenesis as well as tumor immunity. PAQR4 may serve as a potential prognostic biomarker in a variety of cancers.
Efficacy and feasibility of the BREATHE asthma intervention with American Indian children: a randomized controlled trial
Authors: O’Leary Rae A. , O’Leary Marcia A. , Torgerson Dara G. , Mettler Raeann D. , Enright Kendra J. , Best Lyle G. 
Published: December 2022

AbstractAmerican Indian (AI) children experience significant disparities in asthma prevalence, severity, and burden of disease, yet few asthma education interventions are tested in this population. This study aimed to evaluate the efficacy and feasibility of the BREATHE intervention with parents and AI children, during a 3-year follow-up period (n = 108), using a randomized controlled design. Children with asthma identified by electronic medical records (EMR) were screened and matched with 2 controls. The intervention included an initial educational and 24 months of follow-up. The control group continued their usual care. The primary outcome was the frequency of EMR documented, emergency department (ED) visits or hospitalization for respiratory complaints. There was no statistical difference in mean primary outcomes (1.34 (1.98) vs 1.22 (1.95), − 0.88 to 0.63, 95% CI of the difference, p = 0.75), nor percent with any ED visit or hospitalization (29/53, 55% vs 30/55, 54%, p = 0.99) between the intervention or control groups respectively. After 365 days, there was a borderline significant difference in time to primary outcome. Although limited in power, the present study did not demonstrate a persistent effect of this intervention. We recommend that AI pediatric asthma interventions are culturally-designed, use feasible procedures, and repeat education at least every 12 months.
Photon extraction enhancement of praseodymium ions in gallium nitride nanopillars
Authors: Sato Shin-ichiro , Li Shuo , Greentree Andrew D. , Deki Manato , Nishimura Tomoaki , Watanabe Hirotaka , Nitta Shugo , Honda Yoshio , Amano Hiroshi , Gibson Brant C. , Ohshima Takeshi 
Published: December 2022

AbstractLanthanoid-doped Gallium Nitride (GaN) integrated into nanophotonic technologies is a promising candidate for room-temperature quantum photon sources for quantum technology applications. We manufactured praseodymium (Pr)-doped GaN nanopillars of varying size, and showed significantly enhanced room-temperature photon extraction efficiency compared to unstructured Pr-doped GaN. Implanted Pr ions in GaN show two main emission peaks at 650.3 nm and 651.8 nm which are attributed to 3P0-3F2 transition in the 4f-shell. The maximum observed enhancement ratio was 23.5 for 200 nm diameter circular pillars, which can be divided into the emitted photon extraction enhancement by a factor of 4.5 and the photon collection enhancement by a factor of 5.2. The enhancement mechanism is explained by the eigenmode resonance inside the nanopillar. Our study provides a pathway for Lanthanoid-doped GaN nano/micro-scale photon emitters and quantum technology applications.
Land use and land cover changes influence the land surface temperature and vegetation in Penang Island, Peninsular Malaysia
Authors: Akomolafe Gbenga F. , Rosazlina Rusly 
Published: December 2022

AbstractThe ecological changes in vegetation and land of an area can be monitored and managed through the assessment of its past and present land use and land cover (LULC). In this study, we assessed the changes in the LULC of Penang Island between 2010 and 2021. We also determined the corresponding impacts on the land surface temperature (LST) and vegetation index in the form of normalized difference vegetation index (NDVI). Landsat-5 and Landsat-8 were selected for the study. The LULC types were classified using both supervised and unsupervised multivariate maximum likelihood techniques. The LULC change analysis revealed a considerable increase in the urbanized areas (45.71%), a slight increase in the forests (1.57%) and a sizeable reduction in the agricultural/herbaceous areas (− 33.49) of the city within the stipulated period. The urbanized areas were observed to have the highest LST in 2010 and 2021 (28.75–34.0 °C) followed by the bare land (29.76–29 °C). The increase in temperature could have been driven by the reduction in the greenness of the city coupled with the openness of vegetation cover. Similarly, strong positive correlations were observed between the LST and NDVI in the urbanized areas (R2 = 0.92), and bare lands (R2 = 0.86). We, therefore, hypothesize that urbanization is the main driver of the LULC changes on Penang Island.
Influence of naps on sedentary time and physical activity in early childhood
Authors: St. Laurent Christine W. , Lokhandwala Sanna , Allard Tamara , Ji Angela , Riggins Tracy , Spencer Rebecca M. C. 
Published: December 2022

AbstractThe objective was to determine if, in preschool-aged children, (1) nap habituality is associated with sedentary time and physical activity (movement behaviors), (2) nap physiology is associated with movement behaviors, and (3) if missing a nap, compared to taking a nap, affects movement behaviors on the same day and subsequent day. A within-subjects (44 children; 4.2 ± 0.6 years; 55.6% female), at-home study examined two experimental conditions (one afternoon each of nap- and wake-promotion with order counterbalanced) one week apart. Movement behaviors were derived from wrist-worn actigraphy (12.1 ± 3.1 days). Average movement behaviors were calculated from the overall study period with experimental days excluded. Movement behaviors were also extracted for the same day and the subsequent day of the two experimental conditions. Polysomnography was recorded during the nap-promoted condition. Children were classified as non-, intermediate-, or habitual-nappers. Although average movement behaviors were different between nap habituality groups, differences were not significant. There were no associations between movement behaviors and nap sleep stages, and no effects for nap condition or condition by nap habituality on same or next day movement behaviors. Findings do not suggest that naps and movement behaviors are related in children. Although a single missed nap was not detrimental to same or next day movement behaviors, future studies should explore effects of multiple days of subsequent nap restriction to examine potential cumulative effects.
3D printing of cellulose nanocrystals based composites to build robust biomimetic scaffolds for bone tissue engineering
Authors: N’Gatta Kanga Marius , Belaid Habib , El Hayek Joelle , Assanvo Edja Florentin , Kajdan Marilyn , Masquelez Nathalie , Boa David , Cavaillès Vincent , Bechelany Mikhael , Salameh Chrystelle 
Published: December 2022

AbstractCellulose nanocrystals (CNC) are drawing increasing attention in the fields of biomedicine and healthcare owing to their durability, biocompatibility, biodegradability and excellent mechanical properties. Herein, we fabricated using fused deposition modelling technology 3D composite scaffolds from polylactic acid (PLA) and CNC extracted fromFicus thonningii. Scanning electron microscopy revealed that the printed scaffolds exhibit interconnected pores with an estimated average pore size of approximately 400 µm. Incorporating 3% (w/w) of CNC into the composite improved PLA mechanical properties (Young's modulus increased by ~ 30%) and wettability (water contact angle decreased by ~ 17%). The mineralization process of printed scaffolds using simulated body fluid was validated and nucleation of hydroxyapatite confirmed. Additionally, cytocompatibility tests revealed that PLA and CNC-based PLA scaffolds are non-toxic and compatible with bone cells. Our design, based on rapid 3D printing of PLA/CNC composites, combines the ability to control the architecture and provide improved mechanical and biological properties of the scaffolds, which opens perspectives for applications in bone tissue engineering and in regenerative medicine.
Improving service efficiency and throughput of cardiac surgery patients using Monte Carlo simulation: a queueing setting
Authors: Mohammadi Tayeb , Roshanaei Ghodratollah , Faradmal Javad , Sadeghifar Majid , Manafi Babak , Mahjub Hossein 
Published: December 2022

AbstractBed occupancy rate (BOR) is important for healthcare policymakers. Studies showed the necessity of using simulation approach when encountering complex real-world problems to plan the optimal use of resources and improve the quality of services. So, the aim of the present study is to estimate average length of stay (LOS), BOR, bed blocking probability (BBP), and throughput of patients in a cardiac surgery department (CSD) using simulation models. We studied the behavior of a CSD as a complex queueing system at the Farshchian Hospital. In the queueing model, customers were patients and servers were beds in intensive care unit (ICU) and post-operative ward (POW). A computer program based on the Monte Carlo simulation, using Python software, was developed to evaluate the behavior of the system under different number of beds in ICU and POW. The queueing simulation study showed that, for a fixed number of beds in ICU, BOR in POW decreases as the number of beds in POW increases and LOS in ICU increases as the number of beds in POW decreases. Also, based on the available data, the throughput of patients in the CSD during 800 days was 1999 patients. Whereas, the simulation results showed that, 2839 patients can be operated in the same period. The results of the simulation study clearly demonstrated the behavior of the CSD; so, it must be mentioned, hospital administrators should design an efficient plan to increase BOR and throughput of patients in the future.
Time inhomogeneous quantum dynamical maps
Authors: Chruściński Dariusz 
Published: December 2022

AbstractWe discuss a wide class of time inhomogeneous quantum evolution which is represented by two-parameter family of completely positive trace-preserving maps. These dynamical maps are constructed as infinite series of jump processes. It is shown that such dynamical maps satisfy time inhomogeneous memory kernel master equation which provides a generalization of the master equation involving the standard convolution. Time-local (time convolution-less) approach is discussed as well. Finally, the comparative analysis of traditional time homogeneous versus time inhomogeneous scenario is provided.
Study on the inhibitory mechanism of dehydrogenated antioxidants on coal spontaneous combustion
Authors: Zhang Xun , Yu Chen , Lu Bing , Gao Fei , Shan Chuan , Zou Jiahui 
Published: December 2022

AbstractIn order to comprehensively and systematically analyze the reasons why antioxidant inhibitors can scavenge free radicals in coal and inhibit coal spontaneous combustion, this paper studies the effects of VC, TBHQ, EGCG and BHT on coal spontaneous combustion by means of coal spontaneous combustion characteristics experiments and quantum chemical simulation methods. The low-temperature oxidation characteristics of coal were studied through temperature-programmed experiments. The results showed that the CO emission of coal samples with antioxidants was significantly lower than that of raw coal. At 170 °C, the maximum decrease was 37.74%. Fourier infrared test showed that compared with the coal samples without antioxidant treatment, the adsorption strength of hydroxyl structure and oxygen-containing functional groups of the treated coal samples was significantly reduced. The area percentages of hydroxyl and methylene changed significantly, decreased by 7.14% and 6.46%, respectively. Subsequently, molecular models of four antioxidants were constructed using quantum chemical theory, and their Mulliken charges, BDE values ​and frontier orbitals were calculated according to density functional theory (DFT), and the active sites and inhibition mechanisms of antioxidants were discussed. The results showed that H9 of VC, H33 of EGCG, H1 of TBHQ and H40 of BHT all had strong ability to scavenge oxygen-containing free radicals, and their order of strength was TBHQ > BHT > EGCG > VC. Antioxidant inhibitors mainly reduce the number of active free radicals by removing the peroxide groups in the initial stage of the coal oxygen reaction, and remove the hydroxyl groups to prevent the further spontaneous combustion of coal and inhibit the low temperature oxidation process of coal.
A study of pressure-driven flow in a vertical duct near two current-carrying wires using finite volume technique
Authors: Ali Kashif , Jamshed Wasim , Suriya Uma Devi S. , Ibrahim Rabha W. , Ahmad Sohail , Tag El Din El Sayed M. 
Published: December 2022

AbstractFor heating, ventilation or air conditioning purposes in massive multistory building constructions, ducts are a common choice for air supply, return, or exhaust. Rapid population expansion, particularly in industrially concentrated areas, has given rise to a tradition of erecting high-rise buildings in which contaminated air is removed by making use of vertical ducts. For satisfying the enormous energy requirements of such structures, high voltage wires are used which are typically positioned near the ventilation ducts. This leads to a consequent motivation of studying the interaction of magnetic field (MF) around such wires with the flow in a duct, caused by vacuum pump or exhaust fan etc. Therefore, the objective of this work is to better understand how the established (thermally and hydrodynamically) movement in a perpendicular square duct interacts with the MF formed by neighboring current-carrying wires. A constant pressure gradient drives the flow under the condition of uniform heat flux across the unit axial length, with a fixed temperature on the duct periphery. After incorporating the flow assumptions and dimensionless variables, the governing equations are numerically solved by incorporating a finite volume approach. As an exclusive finding of the study, we have noted that MF caused by the wires tends to balance the flow reversal due to high Raleigh number. The MF, in this sense, acts as a balancing agent for the buoyancy effects, in the laminar flow regime
Evaluation of the relationship between the collapsed mechanism and excavation method in tunnels excavated in schists
Authors: Aygar Ebu Bekir 
Published: December 2022

AbstractThe problems experienced in tunnels excavated under high cover in graphitic schists generally vary according to the squeezing mechanism. During the tunnel excavation, slips occur on the slickenside surfaces in the tunnel face from time to time and collapse occurs. Most of the time, failures in the support systems are observed due to the squeezing mechanism in the long term in the sections whose tunnel excavations have been completed. In addition, if tunnel excavations are carried out from both entrance faces, it is possible to encounter excessive deformations at the junction points of the tunnels. Especially on weak ground, the importance of the distances between the stages increases in the case of opening the tunnels in the form of top heading, bench, and invert gradually. As a tunnel excavation method, excavation in stages directly affects the stability of the tunnel. Within the scope of this study, the collapsed mechanism in the junction area of the tunnels of the T6 tunnel is examined. For this purpose, 3-dimensional numerical analysis are performed with the Flac3d program. Analysis results are compared with site deformation measurements. As a result, an excavation methodology is proposed for the junction area of tunnels in weak ground.
Diverse mycorrhizal maize inbred lines differentially modulate mycelial traits and the expression of plant and fungal phosphate transporters
Authors: Giovannini Luca , Sbrana Cristiana , Giovannetti Manuela , Avio Luciano , Lanubile Alessandra , Marocco Adriano , Turrini Alessandra 
Published: December 2022

AbstractFood production is heavily dependent on soil phosphorus (P), a non-renewable mineral resource essential for plant growth and development. Alas, about 80% is unavailable for plant uptake. Arbuscular mycorrhizal fungi may promote soil P efficient use, although the mechanistic aspects are yet to be completely understood. In this study, plant and fungal variables involved in P acquisition were investigated in maize inbred lines, differing for mycorrhizal responsiveness and low-P tolerance, when inoculated with the symbiont Rhizoglomus irregulare (synonym Rhizophagus irregularis). The expression patterns of phosphate transporter (PT) genes in extraradical and intraradical mycelium (ERM/IRM) and in mycorrhizal and control maize roots were assessed, together with plant growth responses and ERM extent and structure. The diverse maize lines differed in plant and fungal accumulation patterns of PT transcripts, ERM phenotypic traits and plant performance. Mycorrhizal plants of the low-P tolerant maize line Mo17 displayed increased expression of roots and ERM PT genes, compared with the low-P susceptible line B73, which revealed larger ERM hyphal densities and interconnectedness. ERM structural traits showed significant correlations with plant/fungal expression levels of PT genes and mycorrhizal host benefit, suggesting that both structural and functional traits are differentially involved in the regulation of P foraging capacity in mycorrhizal networks.
A Framework for Integrating Speech-Language Pathology in an Interdisciplinary Awake Craniotomy Program for Brain Tumor Resection
Authors: Connelly Katherine , Gurd Lauren , Noll Kyle R. , Prabhu Sujit , Kumar Vinodh A. , Hutcheson Katherine A. 
Published: December 2022

Purpose:
The aim of this work was to detail the interdisciplinary awake craniotomy program model at The University of Texas MD Anderson Cancer Center integrating speech-language pathology and neuropsychology in the pre-, intra-, and postoperative settings to monitor and maximize expressive and receptive language skills among patients undergoing brain tumor resection.

Conclusions:
This report outlines the MD Anderson clinical protocols and procedures, with focus on the clinical methods of the speech-language pathologist in pre-, intra-, and postoperative interventions. Case examples are summarized to illustrate dynamic features of implementing this protocol. An intradisciplinary team approach to treatment of patients with brain tumor and specifically those undergoing awake craniotomy may improve care and quality of life.
Priority‐aware intelligent device access management for carbon footprint monitoring in sustainable cites and society
Authors: Su Xiaoyu , Liu Pengju , Wang Zhao , Liao Haijun , Zhou Zhenyu , Xu Guangyuan , Wang Zhenti , Qin Yan 
Published: December 2022

AbstractCarbon footprint monitoring provides significant basis for computing facilities to improve the computing efficiency and reduce the energy cost, which can enable low/zero carbon computing and facilitate the construction of sustainable cites. Massive sensing devices access to 5G base station to transmit collected carbon emission data, which requires intelligent access management. Fast uplink grant possesses the advantages of reducing signalling overhead and access conflicts while facing the problems of incomplete information and difficulty in guaranteeing priority constraint. This paper examines, the maximum access queuing delay minimization problem is formulated under the long‐term service priority constraint and the short‐term access management constraint. First, Lyapunov optimization is leveraged to decouple the long‐term service priority constraint and short‐term access management optimization, and decompose the long‐term stochastic optimization problem into a series of short‐term deterministic problems. Then, a priority‐aware deep Q‐network (DQN)‐based fast uplink grant access management (PDAC) algorithm is proposed to achieve intelligent access management with differentiated service priority requirements. PDAC utilizes DQN to handle non‐convex high‐dimensional optimization problem with service priority constraint to achieve intelligent access management and priority awareness. Simulation results demonstrate that PDAC outperforms the existing algorithms in access queuing delay, buffer queue backlog, and priority deficit fluctuation.