bluuebunny/crossref_metadata_2025_split huggingface dataset:
Supervision of Information Communication Technologies in Social Work Practice: A Mixed Methods Study
Authors: Sewell Karen M , Mishna Faye , Sanders Jane E , Bogo Marion , Milne Betsy , Greenblatt Andrea 
Published: June 2022

Abstract
The integration of informal information and communication technologies (ICTs) has transformed social work practice, yet the use of ICTs in practice is not commonly discussed in supervision. The aim of this sequential mixed methods study was to understand the factors associated with social workers’ discussion of informal ICT use in supervision, and the considerations that influence these discussions. A logistic regression was conducted using data from Canadian #socialwork survey participants in organisational settings (n = 958). Quantitative findings were integrated with the qualitative findings from a reflexive thematic analysis of participant interviews (n = 22), some of which occurred during and were impacted by the COVID-19 pandemic. Based on our integrated findings, supervisory ICT discussion was highly dependent on organisational policy and supervisors’ interpretation of these policies. The setting in which the survey participants worked was also associated with ICT discussion in supervision. In making their decisions to discuss ICT use, interview participants further highlighted the importance of the supervisory relationship based on supervisor qualities and availability.
Multicompartmental models and diffusion abnormalities in paediatric mild traumatic brain injury
Authors: Mayer Andrew R , Ling Josef M , Dodd Andrew B , Stephenson David D , Pabbathi Reddy Sharvani , Robertson-Benta Cidney R , Erhardt Erik B , Harms Robbert L , Meier Timothy B , Vakhtin Andrei A , Campbell Richard A , Sapien Robert E , Phillips John P 
Published: June 2022

Abstract
The underlying pathophysiology of paediatric mild traumatic brain injury and the time-course for biological recovery remains widely debated, with clinical care principally informed by subjective self-report. Similarly, clinical evidence indicates that adolescence is a risk factor for prolonged recovery, but the impact of age-at-injury on biomarkers has not been determined in large, homogeneous samples. The current study collected diffusion MRI data in consecutively recruited patients (n = 203; 8–18 years old) and age and sex-matched healthy controls (n = 170) in a prospective cohort design. Patients were evaluated subacutely (1–11 days post-injury) as well as at 4 months post-injury (early chronic phase). Healthy participants were evaluated at similar times to control for neurodevelopment and practice effects. Clinical findings indicated persistent symptoms at 4 months for a significant minority of patients (22%), along with residual executive dysfunction and verbal memory deficits. Results indicated increased fractional anisotropy and reduced mean diffusivity for patients, with abnormalities persisting up to 4 months post-injury. Multicompartmental geometric models indicated that estimates of intracellular volume fractions were increased in patients, whereas estimates of free water fractions were decreased. Critically, unique areas of white matter pathology (increased free water fractions or increased neurite dispersion) were observed when standard assumptions regarding parallel diffusivity were altered in multicompartmental models to be more biologically plausible. Cross-validation analyses indicated that some diffusion findings were more reproducible when ∼70% of the total sample (142 patients, 119 controls) were used in analyses, highlighting the need for large-sample sizes to detect abnormalities. Supervised machine learning approaches (random forests) indicated that diffusion abnormalities increased overall diagnostic accuracy (patients versus controls) by ∼10% after controlling for current clinical gold standards, with each diffusion metric accounting for only a few unique percentage points. In summary, current results suggest that novel multicompartmental models are more sensitive to paediatric mild traumatic brain injury pathology, and that this sensitivity is increased when using parameters that more accurately reflect diffusion in healthy tissue. Results also indicate that diffusion data may be insufficient to achieve a high degree of objective diagnostic accuracy in patients when used in isolation, which is to be expected given known heterogeneities in pathophysiology, mechanism of injury and even criteria for diagnoses. Finally, current results indicate ongoing clinical and physiological recovery at 4 months post-injury.
Life History ofChrysodeixis includens(Lepidoptera: Noctuidae) on Positively Charged Zein Nanoparticles
Authors: Bonser Colin A R , Astete Carlos E , Sabliov Cristina M , Davis Jeffrey A 
Published: June 2022

AbstractResearch indicates that nanoparticles can be an effective agricultural pest management tool, though unintended effects on the insect must be evaluated before their use in agroecosystems. Chrysodeixis includens (Walker) was used as a model to evaluate chronic parental and generational exposure to empty, positively charged zein nanoparticles ((+)ZNP) and methoxyfenozide-loaded zein nanoparticles (+)ZNP(MFZ) at low-lethal concentrations. To determine concentration limits, an acute toxic response test on meridic diet evaluated (+)ZNP(MFZ) and technical grade methoxyfenozide using two diet assay techniques. No differences in acute toxicity were observed between the two treatments within their respective bioassays. With these results, population dynamics following chronic exposure to low-lethal concentrations were evaluated. Parental lifetables evaluated cohorts of C. includens reared on diet treated with LC5 equivalents of (+)ZNP, (+)ZNP(MFZ), or technical grade methoxyfenozide. Compared to technical grade methoxyfenozide, (+)ZNP(MFZ) lowered both the net reproductive rate and intrinsic rate of increase, and was more deleterious to C. includens throughout its lifespan. This was contrasted to (+)ZNP, which showed no differences in population dynamics when compared with the control. To evaluate chronic exposure to (+)ZNP, generational lifetables reared cohorts of C. includens on LC5 equivalent values of (+)ZNP and then took the resulting offspring to be reared on either (+)ZNP or untreated diet. No differences in lifetable statistics were observed between the two treatments, suggesting that (+)ZNP at low ppm do not induce toxic generational effects. This study provides evidence into the effects of nanodelivered methoxyfenozide and the generational impact of (+)ZNP.
The association between short-term, chronic localized and chronic widespread pain and risk for cardiovascular disease in the UK Biobank
Authors: Rönnegård Ann-Sofie , Nowak Christoph , Äng Björn , Ärnlöv Johan 
Published: June 2022

Abstract

Aims
The interplay between pain of different chronicity and cardiovascular disease (CVD) is incompletely understood. We aimed to investigate the association between different levels of chronic or nonchronic pain and risk of CVD.

Methods and results
Participants in the UK Biobank who reported pain at baseline were divided into three groups according to pain duration and widespreadness. Participants reporting no pain were controls. Multivariable Cox regression was used to investigate the association between pain and incidence of myocardial infarction, heart failure, stroke, cardiovascular mortality, and composite CVD (defined as any of the before-mentioned cardiovascular events). Of 475 171 participants, 189 289 reported no pain, 87 830 reported short-term pain, 191 716 chronic localized pain, and 6336 chronic widespread pain (CWP). During a median of 7.0 years’ follow-up, participants with chronic localized pain and CWP had, after adjustment for age, sex, established cardiovascular risk factors, physical activity, anxiety, depression, cancer, chronic inflammatory/painful disease, pain/anti-inflammatory medication, socioeconomic status, a significantly increased risk for composite CVD [hazard ratio (HR) 1.14, confidence interval (CI) 1.08–1.21, P &lt; 0.001; and HR 1.48, CI 1.28–1.73, P &lt; 0.001, respectively] compared with controls, with similar results when using the different specific CVDs as outcomes. Population attributable risk proportion for chronic pain as a risk factor for composite CVD was comparable with that of diabetes (8.6 vs. 7.3%, respectively).

Conclusion
Chronic pain is associated with an increased risk for myocardial infarction, stroke, heart failure, and cardiovascular death independent of established cardiovascular risk factors, socioeconomic factors, comorbidities and medication. Our study, the largest to date, confirms and extends our understanding of chronic pain as an underestimated cardiovascular risk factor with important public health implications.
Burden of cardiovascular diseases and depression attributable to psychosocial work exposures in 28 European countries
Authors: Sultan-Taïeb Hélène , Villeneuve Tania , Chastang Jean-François , Niedhammer Isabelle 
Published: June 2022

Abstract

Background
This study aimed to estimate the annual burden of cardiovascular diseases and depression attributable to five psychosocial work exposures in 28 European Union countries (EU28) in 2015.

Methods
Based on available attributable fraction estimates, the study covered five exposures, job strain, effort–reward imbalance, job insecurity, long working hours and workplace bullying; and five outcomes, coronary/ischemic heart diseases (CHD), stroke, atrial fibrillation, peripheral artery disease and depression. We estimated the burden attributable to each exposure separately and all exposures together. We calculated Disability-Adjusted Life Years (DALY) rate per 100 000 workers in each country for each outcome attributable to each exposure and tested the differences between countries and between genders using the Wald test.

Results
The overall burden of CHD attributable to the five studied psychosocial work exposures together was estimated at 173 629 DALYs for men and 39 238 for women, 5092 deaths for men and 1098 for women in EU28 in 2015. The overall burden of depression was estimated at 355 665 DALYs for men and 305 347 for women (respectively 3931 and 912 deaths). The three highest burdens in DALYs in EU28 in 2015 were found for depression attributable to job strain (413 938 DALYs), job insecurity (223 200 DALYs) and workplace bullying (209 306 DALYs). Significant differences between countries were observed for DALY rates per 100 000 workers.

Conclusions
Such results are necessary as decision tools for decision-makers (governments, employers and trade unions) when defining public health priorities and work stress preventive strategies in Europe.
Reading Implication: Moral Injury in Heinrich Böll’s Billard um halb zehn and Vasilii Grossman’s Vse techet
Authors: Jones Oliver T 
Published: June 2022

Abstract
This essay demonstrates the usefulness of ‘moral injury’ as a prism for comparative literary research, particularly between the post-National Socialist German and post-Stalinist Russian contexts. I outline a tendency in the study of post-atrocity fiction to focus on psychoanalytically defined notions of trauma. Subsequently, I explain how moral injury, which denotes the damaging psychological ramifications of transgressing one’s moral code, offers a productive lens for considering the literary thematization of morally ambiguous experiences that do not comfortably fit into the categories of victim and perpetrator, a position recently labelled the ‘implicated subject’ by Michael Rothberg. Comparing the West German author Heinrich Böll’s novel Billard um halb zehn and the Soviet writer Vasilii Grossman’s Vse techet, I show how these texts emphasize the importance of individually reckoning with one’s implication in historical violence as a matter of personal integrity. I propose that developing strategies for ‘reading implication’ such as moral injury can foster ethical forms of transnational comparison.
Prior health promotion experience and intervention outcomes in a lay health advisor intervention
Authors: Woodard Nathaniel , Chen Chang , Huq Maisha R , He Xin , Knott Cheryl L 
Published: June 2022

AbstractTraining lay community members to implement health promotion interventions is an effective method to educate medically underserved populations. Some trainings are designed for individuals who already have a health-related background; however, others are developed for those with no previous health promotion experience. It is unknown whether those with backgrounds in health promotion are more effective in this role than those without. This study assessed the relationship between health promotion experience among trained community health advisors (CHAs) and their self-efficacy to implement an evidence-based cancer control intervention, as well as cancer knowledge and screening behavior outcomes among intervention participants. Data were collected from 66 trained CHAs and 269 participants in CHA-led cancer awareness and early detection workshops. CHAs reported high self-efficacy to implement the intervention independent of their health promotion experience. CHA health promotion experience was neither indicative of differences in participant colorectal or breast cancer knowledge at 12 months, nor of changes in participant-reported cancer screening. However, participant prostate cancer knowledge at 12 months was greater when taught by CHAs with previous health promotion experience (P &lt; 0.01). Prior health promotion experience of trained health advisors may not be pivotal across all contexts, but they may affect specific knowledge outcomes.
Development and validation of a Perceived Relocation Stress Scale for older individuals transferred to long-term care facilities in Taiwan
Authors: Chen Shu-Ming , Wu Chiung-Jung 
Published: June 2022

Abstract

Background
The aim of the current study was to develop and validate a Perceived Relocation Stress Scale.

Methods
A cross-sectional research design was used. A total of 175 older adults residing in long-term care facilities in Southern Taiwan for at least 1 y were recruited. An exploratory factor analysis was performed to examine item convergent and discriminant validity. Concurrent validity was checked using the Depression Anxiety and Stress scale. The reliability was analyzed using Cronbach's alpha and intraclass correlation coefficients.

Results
The face and content validity of the scale were verified by adequately measuring the scale items. Factor analysis consisted of four components (challenge/chance, positive appraisal, threat, loss), with a total variance of 67.35%. The content validity was determined by an expert panel to systematically examine the relevance of all items. The results of item convergent and discriminant validity supported the constructs of the scale. The alpha coefficient for the overall scale was .958, indicating good internal consistency reliability.

Conclusions
The Perceived Relocation Stress Scale is a reliable and valid measurement to assess the stress perceived by older individuals being transferred to a long-term care facility.
Addition of probenecid to oral β-lactam antibiotics: a systematic review and meta-analysis
Authors: Wilson Richard C , Arkell Paul , Riezk Alaa , Gilchrist Mark , Wheeler Graham , Hope William , Holmes Alison H , Rawson Timothy M 
Published: June 2022

Abstract

Objectives
To explore the literature comparing the pharmacokinetic and clinical outcomes from adding probenecid to oral β-lactams.

Methods
Medline and EMBASE were searched from inception to December 2021 for all English language studies comparing the addition of probenecid (intervention) with an oral β-lactam [flucloxacillin, penicillin V, amoxicillin (± clavulanate), cefalexin, cefuroxime axetil] alone (comparator). ROBINS-I and ROB-2 tools were used. Data on antibiotic therapy, infection diagnosis, primary and secondary outcomes relating to pharmacokinetics and clinical outcomes, plus adverse events were extracted and reported descriptively. For a subset of studies comparing treatment failure between probenecid and control groups, meta-analysis was performed.

Results
Overall, 18/295 (6%) screened abstracts were included. Populations, methodology and outcome data were heterogeneous. Common populations included healthy volunteers (9/18; 50%) and those with gonococcal infection (6/18; 33%). Most studies were crossover trials (11/18; 61%) or parallel-arm randomized trials (4/18; 22%). Where pharmacokinetic analyses were performed, addition of probenecid to oral β-lactams increased total AUC (7/7; 100%), Cmax (5/8; 63%) and serum t½ (6/8; 75%). Probenecid improved PTA (2/2; 100%). Meta-analysis of 3105 (2258 intervention, 847 control) patients treated for gonococcal disease demonstrated a relative risk of treatment failure in the random-effects model of 0.33 (95% CI 0.20–0.55; I2 = 7%), favouring probenecid.

Conclusions
Probenecid-boosted β-lactam therapy is associated with improved outcomes in gonococcal disease. Pharmacokinetic data suggest that probenecid-boosted oral β-lactam therapy may have a broader application, but appropriately powered mechanistic and efficacy studies are required.
Differences in carcass chilling rate underlie differences in sensory traits of pork chops from pigs with heavier carcass weights
Authors: Price Hannah E , Barkley Kayla E , Lerner Annie B , Harsh Bailey N , Woodworth Jason C , Tokach Mike D , Dritz Steve S , Goodband Robert D , DeRouchey Joel M , O’Quinn Travis G , Allerson Matt W , Fields Brandon , King David A , Wheeler Tommy L , Shackelford Steven D , Boler Dustin D , Dilger Anna C 
Published: June 2022

Abstract
Pork hot carcass weights (HCW) have been increasing 0.6 kg per year, and if they continue to increase at this rate, they are projected to reach an average weight of 118 kg by the year 2050. This projection in weight is a concern for pork packers and processors given the challenges in product quality from heavier carcasses of broiler chickens. However, previous work demonstrated that pork chops from heavier carcasses were more tender than those from lighter carcasses. Therefore, the objective was to determine the effects of pork hot carcass weights, ranging from 90 to 145 kg with an average of 119 kg, on slice shear force and sensory traits of Longissimus dorsi chops when cooked to 63 or 71 °C, and to assess if differences in chilling rate can explain differences in sensory traits. Carcasses were categorized retrospectively into fast, medium, or slow chilling-rates based on their chilling rate during the first 17 h postmortem. Loin chops cut from 95 boneless loins were cooked to either 63 or 71 °C and evaluated for slice shear force and trained sensory panel traits (tenderness, juiciness, and flavor) using two different research laboratories. Slopes of regression lines and coefficients of determination between HCW and sensory traits were calculated using the REG procedure in SAS and considered different from 0 at P ≤ 0.05. As hot carcass weight increased, chops became more tender as evidenced by a decrease in SSF (63 °C β = −0.0412, P = 0.01; 71 °C β = −0.1005, P &lt; 0.001). Furthermore, HCW explained 25% (R2 = 0.2536) of the variation in chilling rate during the first 5 h of chilling and 32% (R2 = 0.3205) of the variation in chilling rate from 5 to 13 h postmortem. Slow- and medium-rate chilling carcasses were approximately 12 kg heavier (P &lt; 0.05) than fast chilling carcasses. Slice shear force of chops cooked to 63 and 71 °C was reduced in slow and medium chilling compared with fast chilling carcasses. Carcass temperature at 5 h postmortem explained the greatest portion of variation (R2 = 0.071) in slice shear force of chops cooked to 63 °C. These results suggest that carcasses tend to chill slower as weight increases, which resulted in slight improvements in sensory traits of boneless pork chops regardless of final degree of doneness cooking temperature.
Markets for Scientific Attribution
Authors: Gans Joshua S , Murray Fiona 
Published: June 2022

Abstract
Formal attribution provides a means of recognizing scientific contributions as well as allocating scientific credit. This article examines the processes by which attribution arises and its interaction with market assessments of the relative contributions of members of scientific teams and communities—a topic of interest for the organizational economics of science and in understanding scientific labor markets. We demonstrate that a pioneer or senior scientist’s decision to co-author with a follower or junior scientist depends critically on market attributions as well as the timing of the co-authoring decision. This results in multiple equilibrium outcomes each with different implications for expected quality of research projects. However, we demonstrate that the Pareto efficient organizational regime is for the follower researcher to be granted co-authorship contingent on their own performance without any earlier pre-commitment to formal attribution. We then compare this with the alternative for the pioneer of publishing their contribution and being rewarded through citations. While in some equilibria (especially where co-authoring commitments are possible) there is no advantage to interim publication, in others this can increase expected research quality.
Comparison of intensity-modulated radiotherapy with the 5-field technique, helical tomotherapy and volumetric modulated arc therapy for localized prostate cancer
Authors: Kita Nozomi , Shibamoto Yuta , Takemoto Shinya , Manabe Yoshihiko , Yanagi Takeshi , Sugie Chikao , Tomita Natsuo , Iwata Hiromitsu , Murai Taro , Hashimoto Shingo , Ishikura Satoshi 
Published: June 2022

Abstract
The outcomes of three methods of intensity-modulated radiation therapy (IMRT) for localized prostate cancer were evaluated. Between 2010 and 2018, 308 D’Amico intermediate- or high-risk patients were treated with 2.2 Gy daily fractions to a total dose of 74.8 Gy in combination with hormonal therapy. Overall, 165 patients were treated with 5-field IMRT using a sliding window technique, 66 were then treated with helical tomotherapy and 77 were treated with volumetric modulated arc therapy (VMAT). The median age of patients was 71 years. The median follow-up period was 75 months. Five-year overall survival (OS) and biochemical or clinical failure-free survival (FFS) rates were 95.5 and 91.6% in the 5-field IMRT group, 95.1 and 90.3% in the tomotherapy group and 93.0 and 88.6% in the VMAT group, respectively, with no significant differences among the three groups. The 5-year cumulative incidence of late grade ≥2 genitourinary and gastrointestinal toxicities were 7.3 and 6.2%, respectively, for all patients. Late grade ≥2 gastrointestinal toxicities were less frequent in patients undergoing VMAT (0%) than in patients undergoing 5-field IMRT (7.3%) and those undergoing tomotherapy (11%) (P = 0.025), and this finding appeared to be correlated with the better rectal DVH parameters in patients undergoing VMAT. Other toxicities did not differ significantly among the three groups, although bladder dose-volume parameters were slightly worse in the tomotherapy group than in the other groups. Despite differences in the IMRT delivery methods, X-ray energies and daily registration methods, all modalities may be used as IMRT for localized prostate cancer.