bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENERAPAN MULTI-OBJECTIVE PARTICLE SWARM OPTIMIZATION UNTUK OPTIMASI FINANCE-BASED SCHEDULING PADA PROYEK SOHO X DI SURABAYA
Authors: Reynaldo Ambrosius Matthew Junius , Prayogo Doddy 
Published: May 2022

Penjadwalan proyek dan kondisi keuangan perusahaan kontraktor untuk pendanaan selama aktivitas proyek merupakan dua aspek penting penentu keberhasilan proyek konstruksi. Konsep finance-based scheduling mengintegrasikan penjadwalan proyek dan pendanaan untuk menghindari pembengkakan biaya dan keterlambatan. Metode metaheuritsik digunakan untuk membantu menyelesaikan permasalahan optimasi finance-based scheduling. Proses optimasi dengan Multi-Objective Particle Swarm Optimization (MOPSO) dilakukan untuk meminimalkan ketiga aspek dalam finance-based scheduling yaitu durasi proyek, besarnya pinjaman dana yang dibutuhkan, dan besarnya bunga dari pinjaman yang dilakukan oleh kontraktor berdasarkan studi kasus proyek SOHO X di Surabaya. Hasil dari proses optimasi adalah solusi-solusi berupa skenario penjadwalan yang dapat dipilih oleh kontraktor berdasarkan what-if analysis sesuai dengan tingkat kepentingan kontraktor.
A detailed process map for clinical workflow of a new biology‐guided radiotherapy (BgRT) machine
Authors: Hwang Min‐Sig , Lalonde Ron , Huq M. Saiful 
Published: May 2022

AbstractPurposeBiology‐guided radiotherapy (BgRT) is a new external beam radiation therapy modality combining PET‐CT with a linear accelerator that has the potential to track and treat one or more tumors in real‐time. The use of PET and radiopharmaceutical tracers introduces new processes that are different from the existing treatment processes. In this study, we have developed a process map for the clinical implementation of a prototype BgRT machine.MethodsA team of 13 members from various radiation therapy disciplines at our institution participated in developing a prospective process map for a prototype BgRT machine. The methodology provided by the AAPM TG 100 report was followed. In particular, the steps unique to the BgRT workflow, using hypofractionated stereotactic body radiation therapy with fluorodeoxyglucose radiolabeled with fluorine‐18 (FDG) to guide beam delivery, were analyzed.ResultsThe multi‐disciplinary team in the department of radiation oncology at our institution developed a prospective process map for the clinical BgRT workflow. By focusing on the appropriate level of detail, 15 major subprocesses, 133 steps, and 248 substeps were identified and the process map was agreed upon as being useful, implementable, and manageable. Seventy‐four steps from nine subprocesses, 55.6% of the whole process, were analyzed to be the BgRT unique steps. They originate mainly from: (1) acquiring multiple PET images at the BgRT machine with separate patient visits, (2) creating a unique biological treatment volume for BgRT plan (PTVBgRT), and (3) BgRT plan optimization and treatment delivery using PET images.ConclusionUsing BgRT to irradiate multiple metastases in the same session will impact clinical workflow, thus a graphical process map depicting the new clinical workflow with an appropriate level of detail is critical for efficient, safe, and high‐quality care. The prospective process map will guide the successful setup and use of the new BgRT system.
Novel approach to semi‐quantification of tracer accumulation in dopamine transporter scan
Authors: Ito Yoshinori , Fujita Naotoshi , Hara Kazuhiro , Tada Tomohiro , Abe Shinji , Katsuno Masahisa , Naganawa Shinji , Kato Katsuhiko 
Published: May 2022

AbstractPurposeAccurate tracer accumulation evaluation is difficult owing to the partial volume effect (PVE). We proposed a novel semi‐quantitative approach for measuring the accumulation amount by examining the approximate image. Using a striatal phantom, we verified the validity of a newly proposed method to accurately evaluate the tracer accumulations in the caudate and putamen separately. Moreover, we compared the proposed method with the conventional methods.MethodsThe left and right caudate/putamen regions and the whole brain region as background were identified in computed tomography (CT) images obtained by single‐photon emission computed tomography (SPECT)/CT and acquired the positional information of each region. SPECT‐like images were generated by assigning assumed accumulation amounts to each region. The SPECT‐like image, approximated to the actual measured SPECT image, was examined by changing the assumed accumulation amounts assigned to each region. When the generated SPECT‐like image most approximated the actual measured SPECT image, the accumulation amounts assumed were determined as the accumulation amounts in each region. We evaluated the correlation between the count density calculated by the proposed method and the actual count density of the 123I solution filled in the phantom. Conventional methods (CT‐guide method, geometric transfer matrix [GTM] method, region‐based voxel‐wise [RBV] method, and Southampton method) were also evaluated. The significance of differences between the correlation coefficients of various methods (except the Southampton method) was evaluated.ResultsThe correlation coefficients between the actual count density and the SPECT count densities were 0.997, 0.973, 0.951, 0.950, and 0.996 for the proposed method, CT‐guide method, GTM method, RBV method, and Southampton method, respectively. The correlation of the proposed method was significantly higher than those of the other methods.ConclusionsThe proposed method could calculate accurate accumulation amounts in the caudate and putamen separately, considering the PVE.
Crop rotation influences yield more than soil quality at a semiarid location
Authors: McVay Kent , Khan Qasim A. 
Published: May 2022

AbstractWinter wheat (Triticum aestivum L.) is often rotated with a fallow in semiarid regions to conserve soil moisture and minimize crop failures. We hypothesized that direct seed systems coupled with intensified and more diverse crop rotations would produce an equivalent or greater annualized grain yield than a traditional winter wheat–fallow (WF) system. Furthermore, continuous cropping would lead to an accumulation of greater soil carbon than the traditional WF. A 6‐yr study was conducted to evaluate crop rotations, which included pea (Pisum sativum L.), lentil (Lens culinaris Medik), lentil as a cover crop, spring wheat, or camelina [Camelina sativa (L.) Crantz] in rotation with winter wheat in 2‐ and 3‐yr rotations. The results of this study averaged over 6 yr showed that increased cropping intensity produced an annualized yield equal to that of WF, provided that either a fallow or a cover crop rather than another grain crop was present prior to winter wheat. The soil quality indices showed particulate organic matter (POM) increased with rotations with greater cropping intensity (1.00 vs. 0.67), although the POM of these rotations was not different from that of WF.
Unidirectional Gaussian One‐Way Steering
Authors: Qars Jamal El 
Published: May 2022

AbstractSteering is a type of quantum nonlocality that exhibits an inherent asymmetry between two observers. In a nondegenerate three‐level laser coupled to a two‐mode squeezed vacuum reservoir, under realistic experimental conditions, the Gaussian steering of two laser modes, and , generated within the cascade transitions, respectively are examined. It is found that the steerability is always higher than that from ; in addition, the steering asymmetry cannot exceed ln 2, which implies that the state never diverges to an extremal asymmetry state. It is shown how squeezed noise can play a constructive role in realizing one‐way steering. As the main result, it is demonstrated that the state can exhibit one‐way steering solely from , which is shown to emerge as a consequence of the fact that the intensity difference of the modes and is verified to remain always positive, irrespective of the physical and environmental parameters of . The generated unidirectional one‐way steering may provide a useful resource for the distribution of the trust in future asymmetric quantum information tasks.
Isolation of an Elusive Phosphametallacyclobutadiene and Its Role in Reversible Carbon−Carbon Bond Cleavage
Authors: Jakhar Vineet K. , Esper Alec M. , Ghiviriga Ion , Abboud Khalil A. , Ehm Christian , Veige Adam S. 
Published: May 2022

AbstractThe reactivity of phosphaalkynes, the isolobal and isoelectronic congeners to alkynes, with metal alkylidyne complexes is explored in this work. Treating the tungsten alkylidyne [tBuOCO]W≡CtBu(THF)2 (1) with phosphaalkyne (10) results in the formation of [O2C(tBuC=)W{η2‐(P,C)−P≡C−Ad}(THF)] (13‐tBuTHF) and [O2C(AdC=)W{η2‐(P,C)−P≡C−tBu}(THF)] (13‐AdTHF); derived from the formal reductive migratory insertion of the alkylidyne moiety into a W−Carene bond. Analogous to alkyne metathesis, a stable phosphametallacyclobutadiene complex [tBuOCO]W[κ2‐C(tBu)PC(Ad)] (14) forms upon loss of THF from the coordination sphere of either 13‐tBuTHF or 13‐AdTHF. Remarkably, the C−C bonds reversibly form/cleave with the addition or removal of THF from the coordination sphere of the formal tungsten(VI) metal center, permitting unprecedented control over the transformation of a tetraanionic pincer to a trianionic pincer and back. Computational analysis offers thermodynamic and electronic reasoning for the reversible equilibrium between 13‐tBu/AdTHF and 14.
Stereokontrollierte Synthese von fluorierten Isochromanen durch Iod(I)/Iod(III)‐Katalyse
Authors: Häfliger Joel , Sokolova Olga O. , Lenz Madina , Daniliuc Constantin G. , Gilmour Ryan 
Published: May 2022

AbstractDer Erfolg von gesättigten, fluorierten Heterozyklen im Anwendungsbereich der modernen Arzneimittel bietet einen Anreiz für die Weiterentwicklung der Hauptgruppenelement‐Katalyse. Motiviert durch die Alleinstellung von Isochromanen im Spektrum der bioaktiven kleinen Molekülen, wurden entsprechende fluorierte Analoga stereoselektiv mithilfe von Iod(I)/Iod(III)‐Katalyse synthetisiert, unter anderem auch, um die metabolische Labilität der benzylischen Position zu umgehen. Die Acetaleinheit ist durch den anomeren Effekt wichtiger Regulator der Konformation. Um die Vielfalt bekannter Fluorozyklisierungsreaktionen mit Cabonsäurederivaten zu erweitern, wurden leicht zugängliche 2‐Vinylbenzaldehyde verwendet (bis zu >95 : 05 d.r. und 97 : 03 e.r.). Bei Betrachtung gemessener Kristallstukturen zeigten sich wichtige stereoelektronische Interaktionen der fluorierten Produkte. Es wurde bestätigt, dass das [CH2‐CHF]‐Fragment als stereoelektronische Nachahmung des [O‐CH(OR)]‐Acetal Motivs betrachtet werden kann.
Optimization of cell wall disruption and lipid extraction methods by combining different solvents from wet Chlorella vulgaris
Authors: Arabian Daryush 
Published: May 2022

AbstractOver the past few decades, microalgae have emerged as a promising option for making lipid‐based bioactive compounds. The purpose of this study was to extract lipids from Chlorella vulgaris. In this study, different cell wall disruption methods such as microwave, liquid nitrogen, ultrasound (US), and bead mill were compared. We selected and optimized two systems based on their efficacy in disrupting cell walls—US and beads mill. Based on the dry weight of C. vulgaris biomass, the maximum lipid extraction by the US was 17.1% and by bead mill was 15.2%. Following cell wall disruption of C. vulgaris, chloroform–methanol (2:1) solvent combination achieved high lipid extraction. However, the hexane–ethanol (1:1) solvent combination was chosen because of its lower toxicity. Specifically, the effect of the solvent‐to‐biomass ratio, the temperature, and the extraction time was investigated. The results indicated that the chloroform–methanol solvent combination yielded optimal results at 8 ml/g solvents to biomass, 45°C, and 60 min and that the hexane–ethanol combination yielded optimal results at 6 ml/g, 35°C, and 73 min, respectively. The highest amount of lipids was obtained from C. vulgaris with 87.6% moisture content. As a cell wall disruption method, the US obtained 20.4% and 16.4% with a combination of chloroform–methanol solvents and hexane–ethanol, respectively. Additionally, bead milling resulted in the highest extraction yield of 17.6% for chloroform–methanol and 13.9% for hexane–ethanol. Based on the results of cell wall disruption, the US method is the most efficient cell wall disruption method in terms of lipid extraction efficiency.
Cashew tree gum for biomaterials engineering: A versatile raw material in consolidation
Authors: de Azevedo Gabriel Assis , Heinrichs Maria Carolina , Moraes Ângela Maria 
Published: May 2022

AbstractIn this review, the focus of discussion is the polysaccharide fraction of cashew gum (CG), an exudate ofAnacardium occidentaleL., a plant typical of hot and humid tropical climates commonly found in northeastern Brazil and from which cashew nuts are extensively commercialized. CG purification, biological activity, and physical–chemical properties are explored in this work, in addition to applications of this biopolymer as a component of biomaterials used to either support, enhance, or replace damaged tissues or improve biological function. Evidence of its successful use to produce a range of biomaterials, from particles to gels and films, and to improve properties of already existing formulations are provided, supporting its versatility in this field of application.
Antibody charge variant modulation by in vitro enzymatic treatment in different Chinese hamster ovary cell cultures
Authors: Xu Jianlin , Santos Johanna , Anderson Nadine S. , Borys Michael C. , Pendse Girish , Li Zheng Jian 
Published: May 2022

AbstractCharge variants represent a critical quality attribute that must be controlled during the development and manufacturing of monoclonal antibodies (mAb). Previously, we reported the development of a cost‐effective enzymatic treatment capable of removing the C‐terminal lysine from a mAb produced by a Chinese hamster ovary (CHO) GS cell line. This treatment resulted in a significant decrease in basic charge variants and a corresponding improvement in the main peak, enabling a longer cell culture production duration for titer improvement. Here, we describe this enzymatic treatment protocol in detail and demonstrate its applicability to two additional mAbs produced by distinct industrial cell lines. The simple addition of carboxypeptidase B (CpB) at a ratio of 1:10,000 (w/w) to whole cell cultures significantly improved the main peaks for both mAbs without affecting other critical quality attributes, including size exclusion chromatography impurities and N‐glycans. Our results demonstrate that this in vitro CpB treatment protocol can be used as a platform strategy to improve main peak for mAbs that exhibit high levels of basic variants attributable to C‐terminal lysines. An in vitro enzymatic treatment in general may be another good addition to existing in vivo CHO cell culture strategies for titer improvement and control of critical quality attributes.
Tricyanoborane‐Functionalized Anionic N‐Heterocyclic Carbenes: Adjustment of Charge and Stereo‐Electronic Properties
Authors: Zapf Ludwig , Peters Sven , Bertermann Rüdiger , Radius Udo , Finze Maik 
Published: May 2022

AbstractThe 1‐methyl‐3‐(tricyanoborane)imidazolin‐2‐ylidenate anion (2) was obtained in high yield by deprotonation of the B(CN)3‐methylimidazole adduct 1. Regarding charge and stereo‐electronic properties, anion 2 closes the gap between well‐known neutral NHCs and the ditopic dianionic NHC, the 1,3‐bis(tricyanoborane)imidazolin‐2‐ylidenate dianion (IIb). The influence of the number of N‐bonded tricyanoborane moieties on the σ‐donating and π‐accepting properties of NHCs was assessed by quantum chemical calculations and verified by experimental data on 2, IIb, and 1,3‐dimethylimidazolin‐2‐ylidene (IMe, IIa). Therefore NHC 2, which acts as a ditopic ligand via the carbene center and the cyano groups, was reacted with alkyl iodides, selenium, and [Ni(CO)4] yielding alkylated imidazoles 3 and 4, the anionic selenium adduct 5, and the anionic nickel tricarbonyl complex 8, respectively. The results of this study prove that charge, number of coordination sites, buried volume (%Vbur) and σ‐donor and π‐acceptor abilities of NHCs can be effectively fine‐tuned via the number of tricyanoborane substituents.
A robust optimized convolutional neural network model for human activity recognition using sensing devices
Authors: Ata Mohamed Maher , Francies Mariam Labib , Mohamed M. A. 
Published: May 2022

AbstractHuman activity recognition has become an expansive field of interest in recent years, both in academic and industrial research. Human Activity recognition (HAR) is concerning the prediction of person's movement or action such as walking, standing, sitting, up and downstairs, etc. Convolutional neural network (CNN) is a key component with deep learning. The main objective of this study is to design and implement an activity recognition algorithm in the state of the art of deep learning systems which accomplish superlative performance to detect human activities. Accordingly, an extensive comparison has been developed between different deep learning algorithms such as classical (CNN) models and Recurrent Neural Network (RNN) models with respect to the major human activities. Furthermore, a robust (CNN) deep learning model has been built up and proposed in order to enhance the recognition precision of human activities. This proposed model uses raw data acquired from a set of inertial sensor and exploring numerous human achas been built up and proposedtivities; sitting, standing, jogging, walking, and etc. Experimental results show that the precision of the proposed deep structure has achieved 97.5% with respect to the NAdam optimizer which would be considered as the most effectively recognizer compared to other deep learning architectures.
The ‘Quantal Newtonian’ First Law: A Complementary Perspective to the Stationary‐state Quantum Theory of Electrons
Authors: Sahni Viraht 
Published: May 2022

AbstractA complementary perspective to the Göttingen‐Copenhagen interpretation of stationary‐state quantum theory of electrons in an electromagnetic field is described. The perspective, derived from Schrödinger‐Pauli theory, is that of the individual electron via its equation of motion or ‘Quantal Newtonian’ First Law. The Law is in terms of ‘classical’ fields experienced by each electron: the sum of the external and internal fields vanishes. The external field is a sum of the electrostatic and Lorentz fields. The internal field is a sum of fields’ representative of Pauli and Coulomb correlations; kinetic effects; electron density; and internal magnetic component. The energy is obtained from these fields. The sources of the fields are expectation values of Hermitian operators. The perspective is elucidated by application to quantum dots in a magnetic field in a ground, excited singlet and triplet states. The relationship of the perspective to Quantal and traditional density functional theories is briefly explained.
A systematic review on neutrophils interactions with titanium and zirconia surfaces: Evidence from in vitro studies
Authors: Elangovan Gayathiri , Mello‐Neto Joao M. , Tadakamadla Santosh K. , Reher Peter , Figueredo Carlos Marcelo S. 
Published: May 2022

AbstractObjectivesThis systematic review aimed to assess in vitro studies that evaluated neutrophil interactions with different roughness levels in titanium and zirconia implant surfaces.Material and MethodsAn electronic search for literature was conducted on PubMed, Embase, Scopus, and Web of Science and a total of 14 studies were included. Neutrophil responses were assessed based on adhesion, cell number, surface coverage, cell structure, cytokine secretion, reactive oxygen species (ROS) production, neutrophil activation, receptor expression, and neutrophil extracellular traps (NETs) release. The method of assessing the risk of bias was done using the toxicological data reliability assessment tool (TOXRTOOL).ResultsTen studies have identified a significant increase in neutrophil functions, such as surface coverage, cell adhesion, ROS production, and NETs released when interacting with rough titanium surfaces. Moreover, neutrophil interaction with rough–hydrophilic surfaces seems to produce less proinflammatory cytokines and ROS when compared to naive smooth and rough titanium surfaces. Regarding membrane receptor expression, two studies have reported that the FcγIII receptor (CD16) is responsible for initial neutrophil adhesion to hydrophilic titanium surfaces. Only one study compared neutrophil interaction with titanium alloy and zirconia toughened alumina surfaces and reported no significant differences in neutrophil cell count, activation, receptor expression, and death.ConclusionsThere are not enough studies to conclude neutrophil interactions with titanium and zirconia surfaces. However, different topographic modifications such as roughness and hydrophilicity might influence neutrophil interactions with titanium implant surfaces.
Corporate social performance and non‐financial reporting in the cruise industry: Paving the way towards UN Agenda 2030
Authors: Di Vaio Assunta , Varriale Luisa , Di Gregorio Angelo , Adomako Samuel 
Published: May 2022

AbstractThis article investigates the role of accounting disciplines in assessing and fostering corporate social performance (CSP) of business organisations to meet the UN Agenda 2030. Drawing from legitimacy theory, this qualitative study analyses if and how non‐financial reporting positively affects and fosters CSP practices and outcomes within the cruise industry. Specifically, using a case study methodology, a major cruise company has been analysed outlining its sustainable behaviour, through the manual content analysis of sustainability reports (2016–2017–2018), in achieving the sustainable development goals (SDGs) introduced by the UN Agenda 2030. The findings outline that the cruise company presents a clear sustainability and community orientation and adopts several initiatives, mostly focused on environmental and social issues, addressed to meet the 17 SDGs, where reputation and positive image have been recognised as the major antecedents in the perspective of CSP. This study contributes to the literature giving a broader and different reading of sustainability reporting as a “booster” of the CSP in meeting the SDGs and a further interesting application of the legitimacy theory, and offers managerial implications to systematise the content of non‐financial reporting by improving the quality of disclosure to achieve the SDGs, with focus on CSP processes, outcomes and ways.