bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is Complexity of Daily Activity Associated with Physical Function and Life-Space Mobility among Older Adults?
Authors: RANTALAINEN TIMO , KOIVUNEN KAISA , PORTEGIJS ERJA , RANTANEN TAINA , PALMBERG LOTTA , KARAVIRTA LAURA , CHASTIN SEBASTIEN 
Published: February 2022

ABSTRACT

Purpose
Information about mobility and physical function may be encoded in the complexity of daily activity pattern. Therefore, daily activity pattern complexity metrics could provide novel insight into the relationship between daily activity behavior and health. The purpose of the present study was to examine the association between the complexity of daily activity behavior and the mobility and physical function among community-dwelling older adults 75, 80, and 85 yr of age.

Methods
A total of 309 participants wore accelerometers concurrently on the thigh and the trunk for at least three consecutive days. Five activity states (lying, sitting, standing, walking, or activity other than walking) were defined in three different temporal grains (5 s, 1 min, and 5 min), and Lempel–Ziv complexity was evaluated. We assessed complexity of daily activity behavior using the life-space mobility and physical function with distance in preferred pace 6-min walk and the Short Physical Performance Battery.

Results
Weak positive associations were observed between the complexity of daily activity and the mobility and physical function at the finest temporal grains in both sexes (Spearman rho = 0.19 to 0.27, P < 0.05). No significant associations were observed in the coarsest temporal grain in either sex.

Conclusions
Lempel–Ziv estimates of daily activity complexity with a fine temporal grain seem to be associated with community-dwelling older adults’ physical function. The coarsest 5-min temporal grain may have smoothed out physiologically meaningful short activity bouts. Because complexity encodes information related to timing, intensity, and patterning of behavior, complexity of activity could be an informative indicator of future physical function and mobility.
The Cost of Return to Play Protocols in Collegiate Athletes Recovering from Coronavirus Disease 2019
Authors: MACNAMARA JAMES P. , MCCOY CODY W. , HENDREN NICHOLAS S. , TIETZE DAVID C. , MILBURN NATHANIEL K. , DABAS NITIKA , MITRANI RAUL D. , GOLDBERGER JEFFREY J. , KIRK K. MICHELE , SHAH JAY P. , BEST THOMAS M. , LEVINE BENJAMIN D. 
Published: February 2022

ABSTRACT

Introduction/Purpose
SARS-CoV-2 infection (COVID-19) can result in myocarditis. Protocols were developed to allow competitive athletes to safely return to play (RTP) after a COVID-19 infection, but the financial impact of these protocols is unknown. Our objective was to determine the differential cost of post–COVID-19 RTP protocols for competitive collegiate athletes.

Methods
This multicenter retrospective cohort study of clinical evaluation of 295 athletes after COVID-19 infection was performed at four institutions with three RTP protocols. Costs were calculated using adjusted Center for Medicare and Medicaid Services pricing. All athletes underwent electrocardiogram and clinical evaluation. A tiered approach performed cardiac imaging and biomarker analysis for major symptoms. A universal transthoracic echocardiogram (TTE) approach performed TTE and biomarkers for all athletes. A universal exercise stress echocardiogram (ESE) approach performed ESE and biomarkers for all athletes.

Results
The cost per athlete was $632.51 ± 651.80 ($44,908 total) in tiered group (n = 71), $1,072.30 ± 517.93 ($87,928 total) in the universal TTE group (n = 82), and $1357.38 ± 757.05 ($192,748 total) in the universal ESE group (n = 142) (P < 0.001). Extrapolated national costs for collegiate athletes would be $39 to 64 million higher for universal imaging approaches versus a tiered approach. Only seven athletes had probable/possible myocarditis with no significant difference between approaches.

Conclusions
Cardiac screening in collegiate athletes after COVID-19 infection resulted in significant cost to the health care system. A tiered-based approach was more economical, and a universal exercise echocardiogram group detected slightly more myocardial abnormalities by cardiac magnetic resonance imaging. The clinical consequences of these approaches are unknown.
Cool-Water Immersion Reduces Postexercise Quadriceps Femoris Muscle Perfusion More Than Cold-Water Immersion
Authors: MAWHINNEY CHRIS , HEINONEN ILKKA , LOW DAVID A. , HAN CHUNLEI , JONES HELEN , KALLIOKOSKI KARI K. , KIRJAVAINEN ANNA , KEMPPAINEN JUKKA , DI SALVO VALTER , LOLLI LORENZO , CABLE N. TIM , GREGSON WARREN 
Published: February 2022

ABSTRACT

Purpose
The muscle perfusion response to postexercise cold-water immersion (CWI) is not well understood. We examined the effects of graded postexercise CWI upon global and regional quadriceps femoris muscle perfusion using positron emission tomography and [15O]H2O.

Methods
Using a matched-group design, 30 healthy men performed cycle ergometer exercise at 70% V̇O2peak to a core body temperature of 38°C, followed by either 10 min of CWI at 8°C, 22°C, or seated rest (control). Quadriceps muscle perfusion; thigh and calf cutaneous vascular conductance; intestinal, muscle, and local skin temperatures; thermal comfort; mean arterial pressure; and heart rate were assessed at preexercise, postexercise, and after CWI.

Results
Global quadriceps perfusion was reduced beyond the predefined minimal clinically relevant threshold (0.75 mL per 100 g·min−1) in 22°C water versus control (difference (95% confidence interval (CI)), −2.5 (−3.9 to −1.1) mL per 100 g·min−1). Clinically relevant decreases in muscle perfusion were observed in the rectus femoris (−2.0 (−3.0 to −1.0) mL per 100 g·min−1) and vastus lateralis (−3.5 (−4.9 to −2.0) mL per 100 g·min−1) in 8°C water, and in the vastus lateralis (−3.3 (−4.8 to −1.9) mL per 100 g·min−1) in 22°C water versus control. The mean effects for vastus intermedius and vastus medialis perfusion were not clinically relevant. Clinically relevant decreases in thigh and calf cutaneous vascular conductance were observed in both cooling conditions.

Conclusions
The present findings revealed that less noxious CWI (22°C) promoted clinically relevant postexercise decreases in global quadriceps muscle perfusion, whereas noxious cooling (8°C) elicited no effect.
Effects of Exercise Training on the Renin–Angiotensin System in the Kidneys of Dahl Salt-Sensitive Rats
Authors: SAKUYAMA AKIHIRO , OGAWA YOSHIKO , XU LUSI , KOMATSU MIWA , MIURA TAKAHIRO , NAMAI-TAKAHASHI ASAKO , KOHZUKI MASAHIRO , ITO OSAMU 
Published: February 2022

ABSTRACT

Purpose
Exercise training (Ex) has antihypertensive and renal protective effects; however, the precise mechanisms remain unclear. The renal renin–angiotensin system (RAS) plays a vital role in renal function and pathology. Therefore, we investigated the effects of Ex on the renal RAS components in Dahl salt-sensitive (Dahl-S) rats.

Methods
Male Dahl-S rats were divided into four groups: normal salt diet + sedentary, normal salt diet + Ex, high-salt diet (HS, 8% NaCl) + sedentary, and HS + Ex. Treadmill running was performed for 8 wk in the Ex groups.

Results
Ex attenuated the HS-induced renal dysfunction and glomerular injury without causing blood pressure alterations. HS increased urinary excretion of both total and intact angiotensinogen. Ex decreased the HS-induced increased urinary excretion of total angiotensinogen. However, it did not change the HS-induced urinary excretion of intact angiotensinogen, indicating reduced intact angiotensinogen cleaving. Ex restored the HS-induced increased angiotensinogen and angiotensin II type 1 receptor expressions in the outer medulla and the HS-induced increased angiotensin-converting enzyme expression in the cortex. Ex restored the HS-induced decreased renin expression in the cortex and outer medulla, and the HS-induced decreased angiotensin-converting enzyme 2, angiotensin II type 2 receptor, and Mas receptor expressions in the outer medulla.

Conclusions
Ex attenuates HS-induced renal dysfunction, glomerular injury, and renal RAS dysregulation in Dahl-S rats.
Aneurysmal bone cyst on top of fibro-osseous lesion of the ethmoid sinus with orbital and intracranial extension in a child
Authors: Elsayed Ayman Ahmed , Mohamed Rawia Mubarak Hamad , Devine John Charles , Wasserberg Jonathan , Elbadawey Mohamed Reda , Abdelsamad H. S. S. , Sajid Sameeha , Mansour Zeenah Ryad 
Published: March 2022

Objective Aneurysmal bone cysts (ABCs) rarely involve the cranium. We report a case arising in the ethmoid sinus with orbital and intracranial invasion. Imaging suggested an associated fibro-osseous lesion. The lesion was completely resected. Histology confirmed the imaging diagnosis of ABC on top of an ossifying fibroma. A multidisciplinary approach is essential for optimal surgical outcomes. Methods We report a case of an 8-year-old boy with a 5 week history of painless, increasing prominence of the left eye. Clinical examination revealed non-pulsatile left proptosis. Visual acuity and ocular movements were normal. CT and MRI scans of the maxillofacial regions showed a large space-occupying lesion involving the left ethmoid air cells with left orbital and left inferior frontal intracranial extension. Multiple fluid levels with blood products were seen. Areas of the bony component of the lesion showed ground-glass density on CT. Imaging was consistent with an ABC with an underlying fibro-osseous lesion; probably fibrous dysplasia which was confirmed after surgical removal of the lesion. A multidisciplinary team of maxillofacial, neurosusugery and ENT surgeons performed the surgery. Results ABC arising from an osseous fibroma of the skull is rare. Total resection can be achieved with a multidisciplinary surgical approach. Post-operative histology confirmed by the imaging findings.
Non-suicidal self-injurious behavior among the Saudi population: a systematic review
Authors: Bahamdan Ahmed , Aldhawyan Adam 
Published: March 2022

Background: Self-harm is a serious public health problem across the world, impacting not only people who self-harm but also their families and society as a whole through higher resource costs and productivity losses. This review was conducted among the general Saudi population to investigate the prevalence of non-suicidal self-injury (NSSI) and factors affecting it. Methods: An electronic literature search of four major databases, PubMed, Web of Science, Scopus Science Direct, and Google Scholar, was conducted to include eligible studies. All studies reporting NSSI or relevant to the subject were included. Results: A total of five articles with 1758 participants were included. The lowest recorded NSSI prevalence was 0.47% while the highest was 10.2%, both in Al-Khobar city. Conclusion: We recorded a relatively low but increasing prevalence of NSSI. The review also demonstrated that NSSI was more common among the female population and young people. Self-poisoning, including drug overdose, was the most prevalent method of self-harm. Interpersonal difficulties, marital problems, academic failure, and family and self-conflicts were common motivating factors of NSSI.
Comparison of the clinical effectiveness of self-etch sealant with the conventional acid-etch sealant for the retentive ability and marginal integrity in permanent molars: a split mouth one year randomized controlled trial
Authors: Gupta Deveshi , Rao Arathi , Shenoy Ramya , Suprabha Baranya Srikrishna 
Published: March 2022

Background: Self-etching has been shown to be beneficial compared to the other resin sealants especially in pediatric practice. The present in-vivo study was designed to clinically evaluate the sealing ability and retention of the self-etching sealant compared to the conventional resin sealant. The aim was to evaluate and compare the retention and marginal integrity of the self-etch and acid etch sealant materials at three, six and twelve-month follow up. Methods: This was designed a randomized controlled trial, with double blind parallel, split-mouth design. In total, 35 children (70 teeth) between 7 and 10 years of age formed part of the study. Group 1 received acid-etch sealant and Group 2 received self-etch sealants. The study participants and the investigator who performed the statistical analysis were blinded to the treatment allocation. All the samples were evaluated at 3, 6, and 12 months. The inter-group and intragroup comparison were carried out using the Chi-Square test and Friedman test with level of significance set at 5% and the P value less than 0.05. Results: Complete retention of sealants was observed in 34.5% of conventional acid etch (group 1) and 22.9% of self-etch samples (group 2) whereas complete loss of sealants were seen in 11.4% of group 1 and 20% of the group 2 samples and intergroup comparison of retention failure was non-significant (p=0.135). In total, 85.7% of the group 1 and 82.9% of the group 2 samples exhibited good marginal integrity with no clinical changes in the enamel around the margins but this was not statistically significant (p=0.5). Conclusions: Sealants with fewer procedural steps and those which provide adequate retention would be ideal for use in children. Thus, self-etch sealants have been found to be effective and efficient as a sealant in the present in-vivo study. Clinical Trials Registry, India registration: CTRI/2019/03/018343 (29/03/2019).
Water, sanitation and the risk of chronic diseases in old age: Results from the Ghana WHO SAGE 2
Authors: Gyasi Razak M , Simiyu Sheillah , Bagayoko Moussa 
Published: March 2022

Background: The associations of water and sanitation with population health have been well-documented. However, the specific effects of water and sanitation on chronic diseases in old age are least explored. This study examines the associations between water, sanitation and chronic diseases among older people in Ghana and whether these associations are moderated by sex and spatial variation. Methods: Data from the WHO-SAGE Wave 2 involving adults aged ≥ 50 years were analyzed. Chronis diseases were assessed based on the self-reported diagnosis by a healthcare professional. The exposures included water sources, type of toilet, and sharing of toilet facilities. Generalized logistic regression models estimated the effects of water and sanitation indicators on chronic diseases. Results: Overall, 18.8% of the sample reported at least one chronic disease. Compared to men and those in rural areas, women and urban residents respectively were more likely to report chronic disease (p < 0.001). After full adjustments, logistic regressions showed that the use of unimproved sanitation (OR = 1.732, CI: 1.377–5.418) and sharing of sanitation facilities (OR = 1.624, CI: 1.095–1.320) were associated with higher odds of chronic diseases. However, the use of water did not reach significance (p = 0.125). We found a significant interaction effect for type of toilet × sex (OR = 3.498, CI: 1.744–16.442), source of water × residence (OR = 5.935, CI: 1.320–26.685), and type of toilet × spatial variation (OR = 1.998, CI: 1.462–8.642). Conclusions: The use of unimproved sanitation facilities and the sharing of toilet facilities are associated with the occurrence of chronic diseases among older people. Policy and public health interventions targeted at improving the health and well-being of older people should conspicuously include better access and improved sanitation services.
Parental coronavirus disease vaccine hesitancy for children in Bangladesh: a cross-sectional study
Authors: Ali Mohammad , Ahmed Sohel , Bonna Atia Sharmin , Sarkar Abu-sufian , Islam Md. Ariful , Urmi Tania Akter , Proma Tasnuva Samarukh 
Published: March 2022

Background: Coronavirus disease 2019 (COVID-19) requires mass immunization to control the severity of symptoms and global spread. Data from developed countries have shown a high prevalence of parental COVID-19 vaccine hesitancy. However, parental vaccine hesitancy data in low- and middle-income countries are scarce. This study aimed to assess the prevalence of parental vaccine hesitancy and identify subgroups with higher odds of vaccine hesitancy in parents in Bangladesh. Methods: A cross-sectional study was conducted on the parents of children aged <18 years from October 10, 2021 to October 31, 2021. Parents participated in face-to-face interviews in randomly selected locations in Bangladesh using a vaccine hesitancy questionnaire. Factors associated with COVID-19 vaccine hesitancy were identified using binary logistic regression analysis. Results: Data from 2,633 eligible parents were analyzed. Overall, 42.8% reported COVID-19 vaccine hesitancy for their youngest child. The final model suggested the following factors were associated with hesitancy: children's age; parent's age, religion, occupation, monthly household income, permanent address, living location, status of tobacco use, adherence with regular government vaccination programs (other than COVID-19), perceptions of COVID-19 vaccine efficacy among Bangladeshi children, self-vaccination intentions, reported family members' illness or death from COVID-19, and perceived threat of COVID-19 were the independent predictors of parental COVID-19 vaccine hesitancy. Conversely, participants who were not tobacco users, parents who were very likely to believe that their children or family members could be infected with COVID-19 in the following year and who were very concerned about their children or a family member contracting COVID-19 in the next year had significantly lower odds of COVID-19 vaccine hesitancy. Conclusions: Our study suggested that vaccine hesitation varied based on sociodemographic characteristics, religion, behavior, and perceived COVID-19 threat. Therefore, interventions focused on addressing vaccine hesitancy among specific subgroups are warranted.
I Don’t “Recall”: The Decision to Delay Innovation Launch to Avoid Costly Product Failure
Authors: Kim Byungyeon , Koenigsberg Oded , Ofek Elie 
Published: March 2022

Innovations embody novel features or cutting-edge components aimed at delivering desired customer benefits. Oftentimes, however, we observe the need to recall new products shortly after their introduction. Indeed, a firm may rush an innovation to market in an attempt to pre-empt rivals and capture early demand, yet in so doing forgo rigorous testing, thus subjecting itself to the risk of a product recall. To shed light on this phenomenon, we construct a dynamic game-theoretic model in which firms plan to launch their innovations. Each firm must decide whether to conduct time-consuming quality assurance testing, which ensures no defects or safety problems but delays the launch. If the innovation is released without such testing and a recall occurs, the firm incurs pecuniary costs and faces future reputation damage in marketing the recalled innovation. We investigate the strategic forces behind firms’ testing and launch-timing decisions in this context. The analysis uncovers a novel mechanism, linked to the possibility of a rival going bankrupt, that causes firms to become more inclined to rush to market and take on the risk of product failure even as the negative consequences of a recall increase. The results further demonstrate how firms’ desire to forgo testing exhibits an inverse-U pattern as consumers become more heterogeneous and how competitive forces may induce both firms to forgo testing, although the resulting profits are lower than had they both committed to conduct testing. The framework is extended to examine how product recall considerations affect firms’ research and development (R&D) investments. Although, in general, post-innovation product failure discourages R&D effort, we identify conditions under which an increase in the recall probability stimulates firms to innovate. Several model extensions are presented, and managerial implications are discussed. This paper was accepted by Dmitri Kuksov, marketing. Supplemental Material: The online appendix is available at https://doi.org/10.1287/mnsc.2022.4303 .
Pendampingan Teknis untuk Peningkatan Kualitas Pengolahan Produk Minyak Serai Wangi (Citronella Oil) di AMKE KTH Panderman, Oro Oro Ombo, Batu
Authors: Nasution Aulia Muhammad Taufiq , Hatta Agus Muhamad , Pratama Detak Yan , Setiadi Iwan Cony 
Published: February 2022

Budidaya tanaman sereh wangi serta ekstraksi kandungan minyak atsirinya memiliki nilai yang sangat tinggi untuk meningkatkan perekonomian masyarakat, dan harga produk minyak serai akan ditentukan oleh kualitas ekstraksi minyak serai yang dihasilkan. Sementara itu kualitas hasil ekstraksi ini sangat dipengaruhi oleh banyak faktor, baik saat proses budidaya dilakukan maupun oleh parameter-parameter proses saat ekstraksi dilakukan. Semua faktor2 yang berpengaruh ini perlu distandarkan dan selalu dikontrol dalam pelaksanaannya, serta penting untuk dipahami oleh pelaku budidaya maupun operator mesin proses ekstraksi. Dalam paper ini akan dilaporkan kegiatan pendampingan yang dilakukan oleh Tim Abdimas Departemen Teknik Fisika ITS beserta Tim KKN Tematik Mahasiswa terhadap pada Kelompok Tani Hutan (KTH) Panderman, selaku kelompok petani pelaku budidaya serai wangi di lokasi Area Modal Konservasi dan Edukasi (AMKE) Oro-oro Ombo, Kecamatan Batu, Kota Batu. Kegiatan pendampingan ini ditujukan untuk menambah wawasan pengetahuan dan pemahaman mereka akan faktor-faktor yang perlu diperhatikan untuk bisa menghasilkan produk serai wangi yang berkualitas baik.
Siberian Literature in Socio-Cultural Range
Authors: Smirnov Sergei , Merkulova OLGA 
Published: February 2022

This review gives an idea of the content of the All-Russian scientific and practical conference (with international participation) "Literature of Siberia in the sociocultural space", which was held on September 23-24, 2021, in Irkutsk. The conference was dedicated to the 100th birth anniversary of the literary scientist, critic, researcher, and devotee of Siberian literature - Vasily Prokopyevich Trushkin. The conference was attended by the professor students and colleagues from Irkutsk State University, famous philologists from other Siberian universities - Barnaul, Kemerovo, Krasnoyarsk, Tomsk, Ulan-Ude, researchers, and experts in Siberian literature from Moscow, St. Petersburg, China, USA and India.
Topical issues of the history and theory of Siberian literature, its specificity and features of interaction with general sociocultural phenomena were discussed.
The "geography" of the conference participants, the variety of reports topics, lively discussions and polemics testify to the relevance, great research potential of the cardinal direction of science - literary local history, at the origins of which was Professor Vasily Prokopyevich Trushkin.