bluuebunny/crossref_metadata_2025_split huggingface dataset:
Residual stress control of hot-rolled strips during run-out table cooling
Authors: Wu Hao , Sun Jie , Peng Wen , Zhang Dianhua 
Published: September 2022

Abstract
The strips with good flatness after finish rolling will have flatness defects such as edge wave after run-out table cooling. These defects are caused by the residual stress due to inhomogeneous thermal and microstructural behaviors during the cooling stage. The traditional residual stress control methods rely too much on experience, resulting in poor control effect and poor universality. Therefore, this study proposed two residual stress control methods based on model calculation: water flow central crown, and center wave compensation control. The former is mainly based on controlling the uniformity of strip transverse temperature and microstructure. The latter is mainly controlled by mutual compensation of internal stresses. In this paper, the mathematical models of water flow central crown cooling and critical center wave compensation stress were established respectively. Meanwhile, a post-buckling model of hot-rolled strip was established to calculate the aim flatness value at exit of finishing mill under critical compensation stress. Furthermore, a fully coupled finite element model based on temperature, phase transitions, and stress was developed and it was verified using experimental data. Finally, the above two residual stress control methods were realized in the finite element model. The results showed that the two methods can reduce the residual stress and improve the flatness, and the application of center wave compensation control is more effective.
Molecular Characterization and Antimicrobial Susceptibility of Human Brucella in Northeast China
Authors: Ma Han-rui , Xu Hui-jiao , Wang Xin , Bu Zhao-yang , Yao Teng , Zheng Zun-rong , Sun Yang , Ji Xue , Liu Jun 
Published: September 2022

Abstract
Background
Brucella is a widespread and highly pathogenic bacteria that poses serious threats to public health and animal husbandry. The aim of this study was to identify the characteristics of Brucella spp. in Northeast China, to determine their antimicrobial resistance, and to preliminarily analyze the resistance mechanism.
Methods
In this study, 61 Brucella isolates were identified by abortus-melitensis-ovis-suis polymerase chain reaction, and epidemic potential was clarified by multi-locus sequence analysis. Whole-genome sequencing (WGS) was performed and the antibiotic susceptibility of the Brucella strains against 13 antibiotics was detected with the use of E-test strips.
Results
The results showed that all of the isolates were Brucella melitensis ST8, group CC4 with little genetic variation and obvious geographical characteristics. All 61 Brucella isolates were sensitive to doxycycline, tetracycline, minocycline, levofloxacin, ciprofloxacin, gentamicin, and streptomycin, while 24.6%, 86.9%, 65.6%, 27.9%, 3.3%, and 1.6% were resistant to rifampin, azithromycin, cefepime, cefoperazone/sulbactam, cefotaxime, and meperidine/sulfamethoxazole, respectively. This is the first report of cephalosporin-resistant B. melitensis in China. The WGS results indicated that about 60% of the antibiotic resistance genes were associated with efflux pumps (mainly the resistance nodulation division family).
Conclusions
Brucellosis is usually treated with antibiotics for several months, which can easily lead to the emergence of antibiotic resistance. To ensure the effectiveness and safety of antibiotics for treatment of brucellosis, continuous surveillance of antibiotic susceptibility is especially important.
Rapid clearance of cytokinin controls transition from cell division to expansion during petal development in rose (Rosa hybrida)
Authors: Jing Weikun , Liu Guoqin , Gong Feifei , Deng Yinglong , Liu Jiaqi , Yang Wenjing , Sun Xiaoming , Li Yonghong , Gao Junping , Zhou Xiaofeng , Ma Nan 
Published: September 2022

Abstract
The size of lateral organs is determined by well-coordinated cell proliferation and cell expansion. The transition from cell proliferation to expansion remains a largely unknown question in plant biology. Here, we report that miR159, an evolutionarily conserved microRNA, plays a crucial role in the transition from cell proliferation to expansion in rose (Rosa hybrida) petals through governing rapid cytokinin catabolism. We uncovered that Cytokinin Oxidase/Dehydrogenase 6 (CKX6) is an authentic target of miR159 in petals. Knocking down miR159 levels resulted in the accumulation of CKX6 transcripts and precocious cytokinin clearance, consequently leading to an earlier transition to cell expansion and smaller petals. Conversely, knockdown of CKX6 caused excess cytokinin and delayed cell expansion, mimicking the effects of exogenous cytokinin application. MYB73, a R2R3-type MYB transcription repressor, recruited a co-repressor (TOPLESS) and a histone deacetylase (HDA19) to form a suppression complex, which governed the expression of MIR159 by modulating H3K9 acetylation levels at the MIR159 promoter. This work thus provides insights for ensuring correct timing of cell expansion and organ size via control of cytokinin catabolism.
Comparison of clinical outcomes between intense pulsed light therapy using two different filters in meibomian gland dysfunction: Prospective randomized study
Authors: Jang Joon Hyuck , Lee Koeun , Nam Sang hyu , Kim Jin , Kim Jae Yong , Tchah Hungwon , Lee Hun 
Published: September 2022

Abstract
Purpose
Our study compared treatment efficacy between cut-off and notch filters in intense pulsed light (IPL) therapy through a prospective, randomized paired-eye trial. Additionally, under strict environment allowing only artificial tear, the efficacy of IPL treatment alone was investigated.
Methods
One eye was selected for an acne filter and the other for a 590 nm filter. Identical IPL treatments were applied during four regimens of IPL. Tear break up time (TBUT), Oxford scale, SICCA staining score, tear matrix metalloproteinase-9 expression, tear osmolarity, and OSDI questionnaires were evaluated before and after IPL. Meibomian gland (MG) parameters were measured.
Results
Regardless of filter, TBUT (1.95 ± 1.07 to 4.02 ± 1.58, p < 0.001), OSDI score (65.34 ± 20.66 to 41.34 ± 18.84, p < 0.001), upper lid meibum expressibility (3.08 ± 2.29 to 7.38 ± 1.28, p < 0.001), and lower lid meibum expressibility (2.88 ± 1.86 to 7.49 ± 1.00, p < 0.001) were markedly improved after IPL. Between acne and 590 nm filters, the former tended to show better efficacy in lower lid expressibility (4.94 ± 1.52 vs 4.36 ± 1.58, p = 0.279) and lower lid meibum secretion score (-11.6 ± 4.45 vs -10.1 ± 5.16, p = 0.271), although not statistically significant.
Conclusions
IPL without additional treatment is efficacious in terms of ocular surface, MG, and subjective symptoms. In addition, an acne filter may be a promising option for more MG targeted effect.
Low-temperature Machinability of Hardened Stainless Steel and Its Chip Morphology Evolution
Authors: Wang Wenyuan , Guo Minglong , Gao Hang , Hu Liwen , Wei Zhaocheng 
Published: September 2022

Abstract
The impeller material FV520B hardened stainless steel is a typical difficult-to-machine material. During the cutting process, the force and heat load are large, it is easy to work hardening, the tool fails early, and the chip breaking is difficult, which leads to a series of problems such as low processing efficiency, poor processing quality and high cost. In addition to changing the mechanical properties of materials, low-temperature cooling will also promote forced heat transfer in the cutting area, which is an important development direction for clean cutting in the future. In this paper, the effects of low temperature cooling (18℃~-196℃) on cutting machinability and chip morphology evolution of FV520B were systematically studied from macroscopic and microscopic aspects by setting triaxial milling and orthogonal turning experiments respectively based on low temperature jet formed by mixing liquid nitrogen and compressed air. Explore the influence of different jet temperature on cutting force, cutting vibration, surface roughness and tool life under the conditions of variable cutting speed, variable axial depth and variable feed per tooth; The influence of different jet temperature on chip morphology, chip deformation degree and adiabatic shear zone under variable cutting speed was explored. The analysis of the experimental results shows that: low temperature cutting with liquid nitrogen can significantly improve the machinability of the material FV520B and promote the formation of sawtooth chips. The research in this article lays a practical and theoretical basis for the low-temperature cutting of impeller material FV520B, and provides a potential new process for high-quality, high-efficiency and clean machining of impellers.
Early removal of the infrapatellar fat pad beneficially alters the pathogenesis of moderate stage idiopathic knee osteoarthritis in male Dunkin Hartley guinea pigs
Authors: Afzali Maryam F. , Radakovich Lauren B. , Sykes Madeline M. , Campbell Margaret A. , Patton Kayley M. , Sanford Joseph L. , Vigon Nicole , Ek Ryan , Narez Gerardo E. , Marolf Angela J. , Donahue Tammy L. Haut , Santangelo Kelly S. 
Published: September 2022

Abstract
Background: The infrapatellar fat pad (IFP) is the largest adipose deposit in the knee; however, its contributions to the homeostasis of this organ remain undefined. To determine the influence of IFP on joint health, this study evaluated the progression of osteoarthritis (OA) following excision of the IFP in a rodent model of naturally-occurring disease.
Methods: Male Dunkin-Hartley guinea pigs (n=18) received surgical removal of the IFP in one knee at 3 months of age; contralateral knees received sham surgery as matched internal controls. Mobility and gait assessments were performed prior to IFP removal and monthly thereafter. Animals were harvested at 7 months of age. Ten set of these knees were processed for microcomputed tomography (microCT), histopathology, transcript expression analyses, and immunohistochemistry (IHC); 8 sets of knees were dedicated to microCT and biomechanical testing (material properties of knee joints tissues and anterior drawer laxity).
Results: Fibrous connective tissue (FCT) developed in place of the native adipose depot. Gait demonstrated no significant differences between IFP removal and contralateral hindlimbs. MicroCT OA scores were improved in knees containing the FCT. Quantitatively, IFP-containing knees had more osteophyte development and increased trabecular volume bone mineral density (vBMD) in femora and tibiae. Histopathology confirmed maintenance of articular cartilage structure, proteoglycan content, and chondrocyte cellularity in FCT-containing knees. Transcript analyses revealed decreased expression of adipose-related molecules and select inflammatory mediators in FCTs compared to IFPs. This was verified via IHC for inflammatory mediators. The medial articular cartilage in knees with native IFPs showed an increase in equilibrium modulus, which correlated with increased amounts of magnesium and phosphorus.
Discussion/Conclusion: Formation of the FCT resulted in reduced OA-associated changes in both bone and cartilage. This benefit may be associated with: a decrease in inflammatory mediators at transcript and protein levels; and/or improved biomechanical properties. Thus, the IFP may play a role in the pathogenesis of knee OA in this strain, with removal prior to disease onset appearing to have short-term benefits.
Prevalence, clinical characteristics and echocardiographic parameters of arrhythmias among patients with rheumatic heart disease attending Jakaya Kikwete Cardiac Institute: A prospective cohort study
Authors: Makatu Clara Damascene , Mutagaywa Reuben Kato , Peter Ponsian , Barongo Aileen , Kifai Engerasiya 
Published: September 2022

Abstract

Background
Arrhythmia is a known complication of rheumatic heart disease (RHD). It is critical to recognize arrhythmias early on so that prompt preventative actions and vigilant monitoring may be considered while treating these patients.
Aim
This study aimed at determining the prevalence, clinical characteristics and echocardiographic parameters of arrhythmias among RHD patients attending Jakaya Kikwete Cardiac Institute (JKCI).
Methodology:
Hospital-based cross-sectional study was conducted among 390 patients with an echocardiography diagnosis of RHD aged 18years and above attending JKCI. Demographic and clinical information was documented. Echocardiography and a resting and 24 hours ambulatory Holter monitoring electrocardiography were done. Chi square test was used to determine association between variables and those with a p value ≤ 0.2 were entered in a multivariate logistic regression analysis to determine the independent factors associated with arrhythmias. P value of < 0.05 was considered statistically significant. The receiver operating curve was used to determine the critical point beyond which arrhythmias develop.
Results
Median age was 39 years IQR (30,52). Females were 257(65.9%). Asymptomatic patients were 208 (53.3%). Most patients belonged to NYHA functional class I&II. The most common valve lesion was mitral stenosis 228 (58.5%). Arrhythmias were found in 276 (70.77%) patients, of which 193 (49.5%) patients were from resting ECG and 83/197 (44.7%) patients from holter electrocardiography. Independent factors for arrhythmias were, New York Heart Association (NYHA) functional class III&IV (a0R 4.67, 95% CI 1.82-12.00 p = < 0.01) and severe left atrial diameter enlargement (aOR 7.28, 95% CI 3.17–16.70 p = < 0.01). The critical point beyond which arrhythmias develop was found to be left atrium diameter > 48mm.
Conclusion
We found a high prevalence of arrhythmias among patients with RHD. The independent predictors of arrhythmias were left atrium dilatation and NYHA functional class III-IV. We recommend close monitoring for arrhythmias among RHD patients in sinus rhythm with higher NYHA functional class and dilated left atrium.
An Investigation on the status of Iran's insurance industry in the underwriting of climate change
Authors: Hamzeh Asma , Farzaneh Mohammad Reza , Banimostafaarab Faezeh , Khordadi Mohammad Javad 
Published: September 2022

Abstract
Global warming and as a result the phenomenon of climate change have caused significant changes such as increasing temperature, increasing atmospheric hazards, and decreasing rainfall in recent decades in different regions of the world, especially mid-latitudes like Iran. Providing appropriate strategies for climate change insurance plays an important role in climate change adaptation and mitigation. This research has been done in order to investigate the situation of Iran's insurance industry in the underwriting of climate change. Therefore, in the beginning, insurance plans and coverage and climate change risk management strategies are reviewed in selected developed and developing countries. Then, the experiences of global surveys, including questioning based on the exposure of the American insurance industry, the climate change survey of the Bermuda Monetary Authority, the global survey of the financial plan of the United Nations Environment Program, and the insurance survey of the Scandinavian region regarding climate change are used in order to develop a questionnaire in line with the current situation of Iran country in the field of climate change insurance. Finally, the results of the questionnaire’s analysis distributed among 35 insurance experts on climate change risk management, show that some insurance companies, despite predicting the impact of climate risks in their insurance processes and empowering their employees, don’t have any plan for the assessment and mitigation of greenhouse gases, regular assessment of climate hazards, providing incentives and modeling. Also, the strategy of annual re-pricing and risk-based pricing has the highest priority to face climate change in insurance companies.
JEL classification: Q54, G22
The influence of Resilience, Burnout and Job Satisfaction on Team development in the primary care setting : the Singapore experience
Authors: Chang Qi Chang Tricia , Wong Kay Wye Sabrina , Koh Hui Li , Lee Eng Sing 
Published: September 2022

Abstract
Background
Team-based care is associated with improved quality, cost and access of care and team functioning plays an important role. However, team development may be affected by team member burnout, resilience, job satisfaction, and workplace characteristics. Team-based care was introduced in the National Healthcare Group Polyclinics (NHGP) through the teamlet care model, where small teams consisting of two family physicians, a nurse and care coordinator provided care for a fixed panel of patients, with improved care continuity, comprehensiveness and integration of care. This study aimed to assess burnout, resilience and job satisfaction amongst different healthcare professionals working in NHGP teamlets, and to determine the association with team development.
Methods
A cross-sectional survey study was conducted recruiting all teamlet members. Survey measures included the Team Development Measure (TDM), Maslach Burnout Inventory Human services survey (MBI-HSS), Connor-Davidson Resilience Scale 2 (CD-RISC 2) and War, Cook and Wall’s Job Satisfaction scale. Scores were compared amongst professional groups and the relationship between TDM and the other scores were explored using correlation analysis and multivariable linear regression.
Results
A total of 88 family physicians, 31 nurses and 27 care coordinators completed the survey, giving an overall response rate of 82.3%. Family physicians reported the highest burnout scores in all three MBI subdomains. There were no significant differences in TDM, resilience and job satisfaction scores amongst the health professions. Multivariable linear regression revealed that lower depersonalisation scores, higher job satisfaction scores and social interaction outside of work were significantly associated with higher TDM scores.
Conclusions
The association between depersonalisation, job satisfaction and social interaction outside work with TDM scores could inform the development of future interventions aimed at improving team development. Steps should be taken to address the higher levels of burnout experienced by family physicians.
MOS only nano-watt sub-bandgap voltage reference
Authors: Rashtian Mohammad 
Published: September 2022

Abstract
This paper presents a nano-watt bandgap voltage reference (BGR). The self-cascode structure is provided as a proportional-to-absolute-temperature (PTAT) voltage. Due to the low slope of the PTAT voltage, a voltage divider consisting of five similar MOSFET transistors is presented. The resulting output voltage will be one-fifth of the complementary-to-absolute-temperature (CTAT) voltage and four-fifths of the PTAT voltage. All MOSFETs are standard CMOS transistors biased in the sub-threshold region where one of them is utilized as a diode. Post-layout simulation results using the standard 0.18 µm CMOS process show a nominal output voltage of 0.132 V. The power consumption is 12.7 nW at 0.7 V of the power supply. The average temperature coefficient (TC) is about 28.5 ppm/oC over a temperature range of 0 oC to 100 oC. The proposed BGR occupies a small area of 0.00067 mm2.
Endophytic bacteria improve plant growth through induction of phytohormones related gene expression in jute
Authors: Aktar Nasima , Hossain Md. Sabbir , Amin Mohammad Ruhul , Ahmed Rasel , Ahmed Borhan , Ullah Md. Wali , Hossain Quazi Mosaddeque , Islam Md. Shahidul 
Published: September 2022

Abstract

Plants live in association with complex populations of microorganisms, including Plant Growth-Promoting Rhizobacteria (PGPR) which confers improved growth and enhanced stress tolerance to plants. This large and diverse group includes endophytic bacteria that can colonize the internal tissues of plants. This study aimed to identify the molecular and physiological characteristics of a non-rhizobial bacterial species from the surface-sterilized root of healthy and nematode-infested jute (Corchorus capsularis;Corchorus olitoriusand an advanced variety ofCorchorus olitorius, Robi-1), an annual fiber bearing plant species. Using universal primers to amplify bacterial 16S rDNA, we identified 59 culturable gram-positive bacterial isolates from healthy and nematode-infected jute plants. All the selected isolates were gram-positive ofBacillusandStaphylococcusgenus. The endophytes were positive for pectinase, xylanase, cellulase, and phosphatase, all of which may influence jute physiology. Selected bacterial species increased the root length, shoot length, and germination rate.B. cereussignificantly increased the growth phenotype and biomass ofC. capsularis(CVL-1) whereasS. hominisshowed significant growth increment inC. olitorius(O-9897) and the combination of all bacteria produced the same effect in the advanced line ofC. olitorius(Robi-1). Higher expression of growth-promoting hormones GA-20 and GA-03 oxidase consolidate that plant growth was increased through induction of increased production of growth hormone gibberellin. Altogether, our results demonstrate thatB. cereus(MCN3) andS. hominis(MON1) display plant growth-promoting traits of potential interest for agricultural applications.
A SUR version of the Bichon criterion for excursion set estimation
Authors: Duhamel Clément , Helbert Céline , Zuniga Miguel Munoz , Prieur Clémentine , Sinoquet Delphine 
Published: September 2022

Abstract
Many model inversion problems occur in industry. These problems consist in finding the set of parameter values such that a certain quantity of interest respects a constraint, for example remains below a threshold. In general, the quantity of interest is the output of a simulator, costly in computation time. An effective way to solve this problem is to replace the simulator by a Gaussian process regression, with an experimental design enriched sequentially with a well chosen acquisition criterion. Different inversion-adapted criteria exist such as the Bichon (also known as Expected Feasibility Function) and deviation number criteria. There also exist a class of enrichment strategies (Stepwise Uncertainty Reduction) which select the next point by measuring the expected uncertainty reduction induced by its selection. In this paper we propose a SUR version of the Bichon criterion. An explicit formulation of the criterion is given and test comparisons show good performances on classical test functions.
Traumatic intraoral herniation of buccal fat pad
Authors: Kedia Daksh , Kshirsagar Rajesh , Nair Vivek , Jha Gaurav 
Published: September 2022

Abstract
Intraoral herniation of the buccal fat pad is a rarely encountered injury in the pediatric group population. It presented as a yellowish blood-tinged pedunculated mass of soft tissue which was nontender and non-pulsatile emanating from the left buccal mucosa following minor trauma to the buccal soft tissues at the level of the maxillary occlusal plane near the parotid papilla. The purpose of this case report is to showcase the rare traumatic prolapse of the buccal fat pad in a young girl and its successfully surgical management by repositioning at a delayed time interval.