bluuebunny/crossref_metadata_2025_split huggingface dataset:
STUDI LITERATUR DOUBLE LOOP PROBLEM SOLVING (DLPS) TERHADAP KEMAMPUAN PEMECAHAN MASALAH IPA SISWA SMP
Authors: Permata Silva Ayu Indah , Sunarno Widha , Harlita Harlita 
Published: January 2022

<p>Penelitian ini membahas berbagai literatur tentang model <em>Double Loop Problem Solving</em> (DLPS) sebagai solusi ketika mengembangkan kemampuan siswa SMP dalam memecahkan permasalahan. Instrumen dalam penelitian ini menggunakan tes wawancara untuk guru dan siswa kelas VII SMPN 3 Singosari. Berdasarkan wawancara memperlihatkan kemampuan siswa tergolong rendah ketika memecahan masalah. Terlihat dari prilaku siswa yang pasif ketika proses pembelajaran berlangsung. Kebanyakan siswa berasumsi materi IPA adalah materi yang sulit dipahami, dan membosankan. Hal tersebut terjadi karena siswa ketika proses pembelajaran berlangsung hanya mendengarkan saat guru menjelaskan dan tidak terlibat langsung dalam mengkaji materi yang dipelajari. Guru dalam proses pembelajaran telah menyesuaikan kurikulum 2013 dengan menerapkan model pembelajaran <em>discovery learning</em>, tetapi pada prosesnya guru hanya berceramah ketika menjelaskan materi. Metode yang digunakan adalah studi literatur dan wawancara. Berdasarkan hasil studi literatur dibutuhkan solusi untuk mengatasi masalah tersebut adalah dengan penerapan model pembelajaran<em> Double Loop Problem Solving</em>.</p>
The Correlation of The Knowledge About Menopause With The Readiness Ahead of Menopause For Pre-menopause Women
Authors: Nurma Yunita Agus Eka 
Published: January 2022

<p><strong>Introduction: </strong>In this globalisation era, healthiness becomes a precious thing, especially on reproduction health that becomes worldwide attention. Statistics Indonesia (<em>Badan Pusat Statistik </em>(BPS) stated 15,2% of 118 million women in Indonesia has entered the menopause period. According to the beginning survey of 10 premenopausal women, only 2 women knew menopause symptoms signs.</p><p><strong>Purpose: </strong>To analyze the correlation of the knowledge about menopause with the readiness ahead of menopause for premenopausal women.</p><p><strong>Subject and Method:</strong> The research was quantitative analytics with a cross-sectional design. The research was located in RT 02 RW 23 Wonorejo, Karanganyar. The population of the research was premenopausal women of PKK Dahlia members. The research used simple random sampling with 30 women as the samples. The data was collected by questionnaire and observation sheet. Data analysis was carried out computerized using the SPSS 20.0 program with Chi-Square statistical test.</p><p><strong>Results:</strong> There were 66,7% (20 respondents) that have high knowledge about facing menopause and there were 60% (18 respondents) that ready to face menopause. The statistic test using chi-square resulted in p-value = 0.045 (p&lt;0.05), which means there was a correlation of the knowledge about menopause with the readiness ahead of menopause for premenopausal women.</p><p><strong>Conclusion:</strong> There was a correlation of the knowledge about menopause with the readiness of menopause for premenopausal women.</p>
The Effectiveness of Fried Catfish Cake In Increasing Hemoglobin Levels And Oxygen Saturation In Blood In Pregnant Women
Authors: Suryani Iis Sopiah , Jamil Maria Ulah , Amalia Novianti Rizki , Pratiwi Ajeng Maharani 
Published: January 2022

<p>Iron deficiency anemia mainly affects pregnant women, lactating women and women of childbearing age in general. Many things change in pregnant women in the third trimester of pregnancy. In the third trimester, blood volume is still increasing so pregnant women need foods rich in iron and vitamin C for good iron absorption. Catfish is one of the foodstuffs that is easy to serve and the price is cheaper than other fish. The nutritional content of catfish will increase with the right way of processing. Fresh catfish contains 1.0 mg of iron. After frying, it becomes 1.2 mg. With the condition of pregnant women who are prone to anemia, pregnant women must fulfill their nutrition by adding additional food, which can be in the form of snacks made from catfish so that their fe needs will be met. Catfish, apart from being processed into meatballs, can also be processed into the fried catfish cake. Quasi-experimental research type <em>non randomized pre test post test</em>. The research subjects were pregnant women in the third trimester. The analysis of this study used the <em>Paired t test</em>. Results: the results of research that has been conducted regarding differences in Hb levels in pregnant women in the third trimester before and after being given fried catfish cake, it was found that there were differences in Hb levels before and after treatment, this result was evidenced by the results of the t statistical test where the t<em>count</em> was 10,816 with a significance level of ρ<em><sub>value</sub></em> of 0.000, there is a significant difference because ρ<em><sub>value</sub></em> is smaller than α (0.05). Meanwhile, for oxygen saturation with the Wilcoxon test statistic, the Z value is -3.345 with a significance level of ρ<em><sub>value</sub></em> of 0.001, Thus before and after treatment there is a significant difference because the value is smaller than α (0.05). The brain of fried catfish cake is effective in increasing hemoglobin levels and oxygen saturation in the blood in third trimester pregnant women.</p><p> </p><p> </p>
PERGESERAN PENGGUNAAN KATA SAPAAN OLEH GENERASI MILENIAL BANJAR DI KOTA BANJARBARU
Authors: Suryatin Eka 
Published: January 2022

<p><em>This study was designed to describe the change in greeting words used by the Millennial Floods in Banjarbaru City and the factors that influence them. This study used descriptive qualitative method. Data collection by refer to the method. Data analysis was performed using the matching method and the advanced technique of the Determination of the Determination Element (PUP) technique. The data used consists of greetings used by the millennial generation of Banjar in Banjarbaru. The research data source consisted of utterances delivered by the Banjar millennial generation in Banjarbaru. The results showed the greeting words used by the Banjar millennial generation in Banjarbaru City increased rotation. Occurs when family runs, kinship, and intimacy. The most shifted form of greeting words occurs in the realm of the family, namely the immediate family. The displacement language used by the millennial flood generation, namely Indonesian and languages (Arabic and English) even has the Banjar language itself. Factors that influence change, namely the existence of urbanization, the progress of science and technology, the language of prestige, and generation over.</em></p><p> </p>
CODE-SWITCHING IN WHATSAPP GROUP: A SOCIAL REALTY AMID COVID-19 PANDEMIC
Authors: Rahayu Endang Yuliani , Widyaningrum Agnes , Yulistiyanti Yulistiyanti , Kasprabowo Teguh 
Published: January 2022

The current study examined the use of Code-Switching in WhatsApp Group (WAG) to find out what codes were used and switched among users of WA and in particular to identify the rationales for such a discursive practice in their communication amid Covid-19 Pandemic. Data for this study were screenshots of linguistic exchanges in WAG over a period of two days (weekend). Theoretical framework for the use of Code- Switching was highlighted as the basis of data analysis. Findings reveal that most members of WAG employ intrasentential code-switching. Regarding the rationales of code-switching, most members used code- switching to talk about particular topics and to show emphaty. The study concludes that code switching is a social reality in a multilingual and multicultural society of diverse educational background. It is highly recommended that similar studies be conducted in some wider and more diverse strata of people in the use of CS to support a newly coined term ‘Permanent Code Switching’ (PCS).
Responses to Landslides and Landslide Mapping on the Blue Ridge Escarpment, Polk County, North Carolina, USA
Authors: Wooten Richard M. , Scheip Corey M. , Hill Jesse S. , Douglas Thomas J. , Korte David M. , Cattanach Bart L. , Bozdog G. Nicholas , Isard Sierra J. 
Published: January 2022

ABSTRACT
Landslides occur in Polk County, North Carolina, primarily along the Columbus Promontory of Blue Ridge Escarpment (BRE), which has 400 m of topographic relief and slopes typically &gt;20°. Bedrock is characterized as late Proterozoic to early Paleozoic metamorphic rocks within Paleozoic thrust sheets. On May 18, 2018, ∼200 mm of rainfall over a 3- to 4-hour period triggered numerous debris flows and slides along the BRE, causing one fatality and severe damage to homes and roads. The State Emergency Operations Center tasked the North Carolina Geological Survey to assess slope stability ahead of search and rescue operations and assess damage along the North Pacolet River valley. The loss of life and destruction from the 2018 storm and ongoing threats to infrastructure prompted us to map landslides throughout Polk County in 2019–2021 to fully document the 2018 landslides and place them in the context of past and ongoing landsliding. We mapped 920 varied types of landslides and attribute 241 to the 2018 storm, making it one of the largest events in North Carolina since 2004 with respect to landslide numbers and spatial frequency. The highest concentrations of landslide features in Polk County are along the slopes of the BRE, especially the Pacolet River and Green River valleys. These rivers exploit post-orogenic brittle fractures to form linear reentrants where the May 2018 and other landslides are concentrated. This article describes our landslide response and mapping efforts and relates our findings to the geomorphic and geologic framework and to past landslide events in the region.
Urbanellina, New Name for the Mississippian Foraminiferal Genus Urbanella Malakhova, 1963, Emended Brenckle, 1997
Authors: Brenckle Paul L. 
Published: January 2022

ABSTRACT
In a recent online paper Vachard & Le Coze (2021) pointed out that the Mississippian foraminifer Urbanella Malakhova, 1963, is a homonym of a protozoan described by Schepotieff (1912). Vachard & Le Coze (2021) proposed that Malakhova's genus name be replaced by Banffella Mamet, 1970, that they consider to be a junior synonym as suggested by Reitlinger (1981). Loeblich & Tappan (1987) rejected that synonymy, a conclusion supported by a later morphological study of Urbanella (Brenckle, 1997). Urbanella and Banffella, based on comparison of their type species (Quasiendothyra urbanaMalakhova, 1954, and Endothyra? banffensisMcKay & Green, 1963), share almost no morphological features and are not synonymous as discussed in the following paragraphs. A new name Urbanellina is proposed herein to replace the homonym Urbanella Malakhova, 1963.
PENGARUH MODEL PEMBELAJARAN PROBLEM BASED LEARNING (PBL) TERHADAP MOTIVASI BELAJAR IPS TERPADU PADA MATERI KEGIATAN EKONOMI
Authors: Siti Nurjanah  , Risma Dwi Arisona  
Published: January 2022

ABSTRAK
Penelitian ini merupakan suatu bentuk analisis terhadap model pembelajaran PBL yang diterapkan pada saat proses pembelajaran. Pemilihan model pembelajaran yang tepat sangatlah penting dilakukan, karena hal tersebut merupakan salah satu faktor yang mampu mempengaruhi motivasi belajar siswa. Seperti halnya proses pembelajaran di SMPN 2 Ponorogo yang menggunakan ceramah hasilnya masih kurang efektif, hal tersebut dilihat ketika pelaksanaan magang 2 sebelumnya. Penelitian ini berfokus untuk mengetahui pengaruh model pembelajaran Problem Based Learning terhadap motivasi belajar IPS Terpadu pada materi kegiatan ekonomi. Oleh karena itu peneliti menyusun pertanyaan yang akan dijawab, yaitu: Apakah terdapat pengaruh yang signifikan model pembelajaran Problem Based Learning terhadap motivasi belajar IPS Terpadu pada materi kegiatan ekonomi? Jenis penelitian yang diambil dalam penelitian ini adalah penelitian eksperimen, dimana penelitian ini dilakukan di SMP Negeri 2 Ponorogo, dengan jumlah sampel yang diambil sebesar 64 siswa. Metode penelitian survey dengan teknik pengumpulan data menggunakan angket dan dokumentasi. Hasil pengujian data yang dilakukan dengan menggunakan aplikasi SPSS Versi 25 memperoleh hasil thitung sebesar 3,808 dan ttabel sebesar 1,997 (thitung>ttabel) atau jika dilihat dari sisi sig. 2 tailed 0,000 < 0,05, yang artinya model pembelajaran Problem Based Learning (PBL) mempunyai pengaruh yang signifikan terhadap motivasi belajar IPS Terpadu pada materi kegiatan ekonomi.
ABSTRACT
This research is a form of analysis of the PBL learning model that is applied during the learning process. Choosing the right learning model is very important, because this is one of the faktors that can affect student learning motivation. As with the learning process at SMPN 2 Ponorogo which uses lectures, the results are still ineffective, this can be seen during the implementation of the previous internship 2. This study focuses on determining the effect of the Problem Based Learning model on learning motivation for Integrated Social Studies on economic activity material. Therefore, the researchers compiled the questions to be answered, namely: Is there a significant effect of the Problem Based Learning learning model on the Integrated Social Studies learning motivation on economic activity material?The type of research taken in this study is experimental research, where this research was conducted at SMP Negeri 2 Ponorogo, with a total sample of 64 students. Survey research method with data collection techniques using questionnaires and documentation. The results of data testing performed using the SPSS version 25 application obtained the tcount of 3.808 and ttable of 1.997 (tcount> ttable) or when viewed from the sig side. 2 tailed 0.000 <0.05, which means that the Problem Based Learning (PBL) learning model has a significant effect on the Integrated Social Studies learning motivation on economic activity material.
Clinical and Immunological Characteristics for BK Polyomavirus- associated Nephropathy after Kidney Transplantation
Authors: Siripoon Tanaya , Apiwattanakul Nopporn , Mongkolrattanakul Pannawat , Tongsook Chutatip , Unwanatham Nattawut , Hongeng Suradej , Kantachuvesiri Surasak , Bruminhent Jackrapong 
Published: January 2022

Abstract
Background
BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN) could cause allograft dysfunction among kidney transplant (KT) recipients. Intact BKPyV-specific immunity is correlated with viral containment, therefore clinical and immunological characteristics related to BKVAN after KT needs to be explored.
Methods
We prospectively investigated an association between clinical baseline characteristics, BK polyomavirus (BKPyV)-specific immunity, and BKPyV-associated nephropathy (BKPyVAN) in KT recipients. BKPyV-specific immunity, measured with intracellular cytokine assays, is reported as the percentage of IFN-γ-producing CD4+ T, CD8+ T, natural killer (NK), and NKT cells after large-T antigen and viral capsid protein 1 (VP1) stimulation.
Results
Among 100 KT patients, BKPyVAN occurred in 18% within one-year post-KT. There were 70 patients (70%) who received an induction immunosuppressive therapy. Diabetic nephropathy was significantly associated with BKPyVAN. Among 40 patients who were eligible for the immunological study. In a multivariate analysis, pre-KT %VP1-specific NK cells were independently associated with BKPyVAN (HR, 1.209; 95%CI, 1.055–1.386; P = 0.006). In those with BKPyVAN, the mean %NK (coefficient, 1.202; 95%CI, 0.033–2.371; P = 0.04), %VP1-specific NK (coefficient, 2.602; 95%CI, 1.083–4.121; P = 0.001), and %NKT (coefficient, 0.199; 95%CI, 0.051–0.348; P = 0.008) cells at 1-month post-KT were significantly higher than those pre-KT. Thus, increasing NK, VP1-specific NK, and NKT cell proportions were observed among KT recipients who developed BKPyVAN within the first year.
Conclusion
KT recipients with underlying diabetes and the presence of BKPyV-specific NK- and NKT-cell immunity could be at risk of BKPyVAN after KT. BKPyV-specific innate immune monitoring could potentially stratify those at risk of BKPyVAN among KT recipients. (Thai Clinical Trials Registry, TCTR20190404004)
Sublobar Resection Without Staging and Diagnostic for Tumors &lt;2 cm is no Adequate Therapy for Non-Small Cell Lung Cancer Patients
Authors: Heldwein Matthias B. , Schlachtenberger Georg , Doerr Fabian , Menghesha Hruy , Hagmeyer Lars , Bennink Gerardus , Gaisendrees Christopher , Wahlers Thorsten , Hekmat Khosro 
Published: January 2022

Abstract
Purpose: Sublobar resection is a frequently performed surgical approach for Non-Small Cell Lung Cancer (NSCLC) patients with <2cm nodules. Retrospective studies are claiming that survival rates after sublobar resection are comparable to that after anatomical resection although studies dealing with sublobar resection do not perform guideline-based staging and little to no lymphadenectomy. Methods: 747 patients underwent surgery for NSCLC at our institution between 2012 and 2020. We retrospectively reviewed data of NSCLC patients with <2cm tumors (n=236). Nodal upstaging and lymphangiosis- (L1) and hemangiosis carcinomatosa (V1) were analyzed. pN0 patients were compared to patients with nodal upstaging. One-, three and five-year survival rates were measured. Survival was assessed by Kaplan-Meier curves.Results: Mean tumor size was 1.4cm±0.39 in our cohort. Of our patients, 14% showed a cT1a tumor and 86% of patients cT1b. 24.0±12.3 lymph nodes were dissected and analyzed per patient, and 0.7±2.0 of those were affected. Of our patients, 16.1% showed an L1 affection and 7.6% a V1 affection. Lymph node involvement was diagnosed in 11(4.7%) patients preoperatively. 39(16.5%) patients were upstaged due to lymph node involvement postoperatively (p<0.001). Upstaged patients showed significantly worse 3- (upstaged: 60.6% vs. pN0: 83.2%; p=0.01) and 5-year (upstages: 38% vs. pN0 71.5%; p=0.02) survival rates.Conclusion: Of our patients with <2cm NSCLC 16.5% were nodal upstaged postoperatively. These results underline that lymphadenectomy during surgery is crucial for NSCLC patients irrespective of the tumor size and the surgical approach.
Immunohistochemical Expression of PD-L1 and MDR1 in Breast Tumors: Association with Clinico-Pathological Parameters and Treatment Outcome
Authors: Antony Gisha Rose , Augustine Paul , Sulfath TP , Ajeesh BL , K Jayasree , Krishna KM Jagathnath , S Lakshmi 
Published: January 2022

Abstract
Antitumor immune evasion is a hallmark for the development and progression of cancer. Tumor cells adopt various mechanisms to escape the host immune system recognition. One such mechanism is the over expression of programmed death ligand (PD-L1), a negative T cell regulatory molecule. Because PD-L1 overexpression causes resistance to chemotherapeutic response in many cancers, herein we explored the relationship between PD-L1 and multidrug resistance protein MDR1 in breast cancer. Immunohistochemical evaluation of PD-L1 and MDR1 proteins in 194 breast cancer tissue samples were carried out. The relationship between PD-L1 and MDR1 expression on cancer cells with clinicopathological factors and prognosis was investigated. IHC showed a significant correlation between PD-L1 and MDR1 expression on tumor cells. Increased PD-L1 expression was also associated with lymph node status and tumor grade of the patient. Our results also revealed that the expression of PD-L1 and MDR1 was higher in TNBC subtype compared to other breast cancer subtypes. Therefore a better understanding of the molecular mechanism through which PD-1/PD-L1 pathway contribute to the chemoresistance might bring forth the prognostic significance of PD-L1 and selection of patients who may benefit from immunotherapy.
Visualization of the Process of a Nanocarrier-Mediated Gene Delivery: Stabilization, Endocytosis, Endosomal Escape and Exocytosis of Genes for Intercellular Spreading
Authors: Ma Zhongzheng , Zheng Yang , Chao Zijian , Chen Hongtao , Zhang Yunhui , Yin Meizhen , Shen Jie , Yan Shuo 
Published: January 2022

Abstract
Nanoparticles have been widely applied as gene carrier for improving RNA interference (RNAi) efficiency in medical and agricultural fields. However, the mechanism and delivery process of nanoparticle-mediated RNAi is not directly visualized. Here we synthesized a star polymer (SPc) consisted of a hydrophilic shell with positively-charged tertiary amine in the side chain as a gene nanocarrier, which was taken as an example to investigate the mechanism in gene delivery. The SPc could assemble with dsRNA spontaneously through electrostatic force, hydrogen bond and van der Waals force. Interestingly, the SPc could protect dsRNA from degradation by RNase A, insect hemolymph and immune cells, thus remarkably increasing the stability of dsRNA. Meanwhile, the SPc could efficiently promote the cellular uptake, endosomal escape and active exocytosis for systematic spreading of dsRNA. Transcriptome analysis revealed that the SPc could up-regulate some key genes such as Chc, AP2S1 and Arf1 for activating clathrin-mediated endocytosis. Furthermore, the suppression of endocytosis by a specific inhibitor hindered the cellular uptake of SPc-delivered dsRNA in vitro, and the subsequent RNAi effect was also disappeared in vivo. To our knowledge, our study is the first direct visualization of the detailed cellular delivery process and mechanism of nanocarrier-mediated gene delivery. Above mechanism supports the application of nanocarrier-based RNAi in gene therapy and pest management.
An Image-based Gradation Calculation Method Considering Crushed Stone Morphology
Authors: Jiang Chong , Ding Xin , Pang Li , Deng Liang , Shi Zexiong 
Published: January 2022

Abstract
An image-based gradation calculation method considering crushed stone morphology is proposed in this paper. Eight kinds of crushed stones are prepared to figure out the effect of the particle shape on the gradation. All particles are pictured and the photos are processed to obtain particle shape indices by using the image-based method. A minimum Feret diameter analysis method is used, which can reflect the influence of the particle shape. Then the paper proposes a developed overall regularity to describe the morphology of particles, which is calculated by the weight of three shape indices: aspect ratio, convexity and sphericity. The developed overall regularity is applied on gradation curve equations to provide an image-based gradation calculation method. And the provided method is validated to well fit the actual case. Furthermore, the method is also applied on two examples of gradation designation and the result proves to be feasible and practicable.