bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mindfulness-Based Interventions for Survivors of Lung Cancer and Their Partners: A Systematic Review
Authors: McDonnell Karen Kane , Owens Otis L. , Umari Fattona 
Published: October 2022

Abstract
Background
Survivors of lung cancer and their partners often have complex unresolved physical, psychosocial, and behavioral needs that can negatively affect the survivors’ and partners’ well-being. This systematic review aimed to (1) examine the content and delivery of mindfulness-based interventions (MBIs) and (2) summarize and synthesize the current evidence for effectiveness of MBIs targeting survivors of lung cancer and/or one selected partner (dyads).

Method
Six databases were searched for interventional studies published in English between 1980 and June 2020 using three terms (lung neoplasms, mindfulness, caregivers). For outcome measures, the interventions focused on behavioral change (meditation, yoga, stretching, breathing), symptom management (dyspnea, fatigue, sleep disruption, anxiety, depression, stress reduction), and knowledge. Two reviewers independently assessed article eligibility. One reviewer performed and another independently verified data extraction. The Cochrane risk-of-bias tool for randomized trials was used to critically appraise RCTs.

Results
Searching yielded 307 records, of which 64 were assessed for eligibility. Six studies investigated the impact of an MBI on survivors and partners. Four studies were single-arm feasibility studies; two were RCTs. Two feasibility studies and one RCT recruited romantic couples whereas the others recruited asymmetrical dyads. The single-arm studies reported strong feasibility and acceptability. RCTs reported significant outcomes for reduced cancer-related distress and depression, and improved QOL, self-compassion, mindfulness skills, and rumination.

Conclusion
Dyadic intervention research is a growing field. Few interventions target individuals with lung cancer and their partners. No interventions target partners alone. Future research should evaluate rigorous methodologies that enhance the understanding of independent and interdependent health-related effects within dyads and across relationships and settings.
Balanced incomplete factorization preconditioner with pivoting
Authors: Marín J. , Mas J. 
Published: October 2022

AbstractIn this work we study pivoting strategies for the preconditioner presented in Bru (SIAM J Sci Comput 30(5):2302–2318, 2008) which computes the LU factorization of a matrix A. This preconditioner is based on the Inverse Sherman Morrison (ISM) decomposition [Preconditioning sparse nonsymmetric linear systems with the Sherman–Morrison formula. Bru (SIAM J Sci Comput 25(2):701–715, 2003), that using recursion formulas derived from the Sherman-Morrison formula, obtains the direct and inverse LU factors of a matrix. We present a modification of the ISM decomposition that allows for pivoting, and so the computation of preconditioners for any nonsingular matrix. While the ISM algorithm at a given step computes only a new pair of vectors, the new pivoting algorithm in the k-th step also modifies all the remaining vectors from $$k+1$$

k
+
1

to n. Thus, it can be seen as a right looking version of the ISM decomposition. The results of numerical experiments with ill-conditioned and highly indefinite matrices arising from different applications show the robustness of the new algorithm, since it is able to solve problems that are not possible to solve otherwise.
Hepatitis D virus infection in a large cohort of immigrants in southern Italy: a multicenter, prospective study
Authors: Pisaturo Mariantonietta , Alessio Loredana , Di Fraia Alessandra , Macera Margherita , Minichini Carmine , Cordua Emanuele , Onorato Lorenzo , Scotto Gaetano , Di Caprio Giovanni , Calò Federica , Sagnelli Caterina , Coppola Nicola 
Published: October 2022

Abstract
Background
Since few data are available in the literature on the prevalence of anti-Delta-positive subjects in immigrant populations, the aim of the present study was to evaluate the demographic and virological characteristics of HDV infection in a large cohort of immigrants living in southern Italy.

Methods
Between January 2012 and February 2020 all immigrants attending one of the 5 first- level centers were enrolled and screened for HBsAg, the HBsAg-positive for anti-Delta and if positive, for HDV-RNA and HDV genotype.

Results
Of the 3521 immigrants observed in the study period, 3417 (97.0%) agreed to be screened; they were mainly males (61%), with a median age of 27 years (IQR 8–74) and came prevalently (58%) from sub-Saharan Africa.
Of the 3417 patients enrolled, 319 (9%) subjects were HBsAg-positive, and of those, 8 (2.5%) were anti-Delta-positive. No difference in the demographic and epidemiological characteristics was observed between the anti-Delta-negative vs -positive. Of the 8 anti-Delta-positive subjects, only one was HDV-RNA-positive (viral load: 7050 IU/mL), genotype 1, with clinical signs of cirrhosis.

Conclusions
the present study showed a prevalence of HDV of 2.5% in a large cohort of asymptomatic immigrants, suggesting the need for screening campaigns for viral infections including delta hepatitis in this population.
Does perfectionism influence individual financial risk tolerance and financial well-being? Evidence from an online survey data from the US
Authors: Wang Di , McGroarty Frank 
Published: October 2022

AbstractPerfectionism influences various aspects of our lives, such as academic study, music, athletics, and work. Perfectionism has two essential facets: striving and evaluative concerns. The effect of perfectionism on financial domain was rarely examined. This study aims to investigate whether perfectionism influence tolerance for financial risk, wealth accumulation and gambling behavior. We implement a cross-sectional study with an online survey sample of 661 US residents. We conduct OLS, quantile and ordered logistic regressions as well as mediation tests to examine the relationships between the variables of interest. The results suggest three findings. First, perfectionistic striving is positively associated with financial risk tolerance, but perfectionistic concerns have no impact on financial risk tolerance. Second, perfectionistic striving (concerns) positively (negatively) predicts liquid wealth mediated by investment knowledge. Third, perfectionistic concerns inhibit gambling expenditure. This study contributes to theory by documenting that perfectionism can influence financial satisfaction or well-being. The conclusions also have important implication from a policy perspective.
Decadal and Annual Variations in Meteoric Flux From Ulysses, Wind, and SOFIE Observations
Authors: Hervig Mark E. , Malaspina David , Sterken Veerle , Wilson Lynn B. , Hunziker Silvan , Bailey Scott M. 
Published: October 2022

AbstractOur solar system is filled with meteoric particles, or cosmic dust, which is either interplanetary or interstellar in origin. Interstellar dust (ISD) enters the heliosphere due to the relative motion of the sun and the interstellar flow. Interplanetary dust (IPD) comes primarily from asteroid collisions or comet sublimation, and comprises the bulk of material entering Earth's atmosphere. This study examines variations in ISD and the IPD flux at Earth using observations from three different satellite techniques. First are size‐resolved in situ meteoroid detections by the Ulysses spacecraft, and second are in situ indirect dust observations by Wind. Third are measurements of meteoric smoke in the mesosphere by the Solar Occultation For Ice Experiment (SOFIE). Wind and Ulysses observations are sorted into the interstellar and interplanetary components. Wind ISD show the anticipated correlation to the 22‐year solar magnetic cycle, and are consistent with model predictions of ISD. Because Wind does not discriminate particle size, the IPD measurements were interpreted using meteoric mass distributions from Ulysses observations and from different models. Wind observations during 2007–2020 indicate a total meteoric influx at Earth of 22 metric tons per day (t d−1), in reasonable agreement with long‐term averages from SOFIE (25 t d−1) and Ulysses (32 t d−1). The SOFIE and Wind influx time series both show an unexpected correlation to the 22‐year solar cycle. This relationship could be an artifact, or may indicate that IPD responds to changes in the solar magnetic field.
Poroelastic Mechanical Behavior of Crystal Mush Reservoirs: Insights Into the Spatio‐Temporal Evolution of Volcano Surface Deformation
Authors: Alshembari Rami , Hickey James , Williamson Ben J. , Cashman Katharine 
Published: October 2022

AbstractCharacterizing the physical properties and mechanical behavior of melt reservoirs is essential for enhancing geophysical models that aim to understand the evolution of subvolcanic systems and support hazard forecasting. Increasing evidence suggests that shallow magmatic reservoirs consist of variably packed crystal frameworks with small volumes of interstitial melt, commonly referred to as “mushes.” Current volcano deformation models often implement static magma sources with a cavity and thus provide little insight into dynamic internal reservoir processes; they also ignore the presence of crystals, melt and other fluids, and therefore the likely poroelastic mechanical response to melt addition or withdrawal. Here we investigate the influence of poroelastic mechanical behavior on reservoir pressure evolution and resultant spatio‐temporal surface deformation. We consider the melt reservoir to be largely crystalline (10%–50% melt fraction) with melt distributed between crystals; we show that the presence of crystals affects the spatial and temporal mechanics of magma reservoir behavior. In contrast to classical models for volcanic surface deformation, our results suggest that a poroelastic surface deformation response continues to develop after withdrawal/upward emplacement of melt has terminated, and importantly that the withdrawal/injection point can affect the evolution of the relative magnitudes of vertical and radial deformation over time. These protracted displacements are caused by melt diffusion, which depends principally on mush hydraulic properties and melt characteristics. Following an intrusion/withdrawal event, a steady state is eventually reached when the fluid pressure is uniform in the mush reservoir.
Low-hysteresis, pressure-insensitive, and transparent capacitive strain sensor for human activity monitoring
Authors: Wang Xiaoyi , Deng Yang , Jiang Peng , Chen Xingru , Yu Hongyu 
Published: October 2022

AbstractWearable strain sensors have been widely used for human activity monitoring. Most reported strain sensors have mainly focused on material engineering, high stretchability and large gauge factors. Few works have focused on strain sensor’s robustness and reliability, including low hysteresis, good long-term stability, good electrode material stability, and low coupling effects under multi-input signals, which are the factors that limit practical strain sensor applications. To develop a high-performance strain sensor, we propose a flexible capacitive sensor structure with three-dimensional (3D) interdigital electrodes fabricated by vertically aligned carbon nanotubes. Compared with a traditional resistive strain sensor and a capacitive strain sensor with vertical sandwich electrodes, a strain sensor with horizontal parallel interdigital electrodes can benefit from low cross talk in terms of the normal force and improve substrate transparency. Additionally, embedding 3D electrodes into the substrate improves ultrahigh robustness with a low-pressure coupling effect under normal force. Moreover, compared with other reported works, the electrode variation under strain is small (less than 1.6%), which means that the perturbation of inert properties on device performance is small. Finally, the fabricated strain sensor achieves an ultralow hysteresis (0.35%), excellent pressure-insensitive performance (less than 0.8%), fast response (60 ms), good long-term stability, and good transparency. As an application example, a flexible strain sensor was successfully demonstrated as a wearable device for the precise monitoring of different types of human activities, including bending of the finger, knee, elbow, wrist, and neck with large strain signals and small strain signals generated by a mouth-opening activity. This excellent performance indicates that the flexible strain sensor is a promising candidate for human motion detection, soft robotics, and medical care.
Distribution of fitness effects of cross-species transformation reveals potential for fast adaptive evolution
Authors: Rathmann Isabel , Förster Mona , Yüksel Melih , Horst Lucas , Petrungaro Gabriela , Bollenbach Tobias , Maier Berenike 
Published: October 2022

Abstract
Bacterial transformation, a common mechanism of horizontal gene transfer, can speed up adaptive evolution. How its costs and benefits depend on the growth environment is poorly understood. Here, we characterize the distributions of fitness effects (DFE) of transformation in different conditions and test whether they predict in which condition transformation is beneficial. To determine the DFEs, we generate hybrid libraries between the recipient Bacillus subtilis and different donor species and measure the selection coefficient of each hybrid strain. In complex medium, the donor Bacillus vallismortis confers larger fitness effects than the more closely related donor Bacillus spizizenii. For both donors, the DFEs show strong effect beneficial transfers, indicating potential for fast adaptive evolution. While some transfers of B. vallismortis DNA show pleiotropic effects, various transfers are beneficial only under a single growth condition, indicating that the recipient can benefit from a variety of donor genes to adapt to varying growth conditions. We scrutinize the predictive value of the DFEs by laboratory evolution under different growth conditions and show that the DFEs correctly predict the condition at which transformation confers a benefit. We conclude that transformation has a strong potential for speeding up adaptation to varying environments by profiting from a gene pool shared between closely related species.
Outcomes among confirmed cases and a matched comparison group in the Long-COVID in Scotland study
Authors: Hastie Claire E. , Lowe David J. , McAuley Andrew , Winter Andrew J. , Mills Nicholas L. , Black Corri , Scott Janet T. , O’Donnell Catherine A. , Blane David N. , Browne Susan , Ibbotson Tracy R. , Pell Jill P. 
Published: October 2022

AbstractWith increasing numbers infected by SARS-CoV-2, understanding long-COVID is essential to inform health and social care support. A Scottish population cohort of 33,281 laboratory-confirmed SARS-CoV-2 infections and 62,957 never-infected individuals were followed-up via 6, 12 and 18-month questionnaires and linkage to hospitalization and death records. Of the 31,486 symptomatic infections,1,856 (6%) had not recovered and 13,350 (42%) only partially. No recovery was associated with hospitalized infection, age, female sex, deprivation, respiratory disease, depression and multimorbidity. Previous symptomatic infection was associated with poorer quality of life, impairment across all daily activities and 24 persistent symptoms including breathlessness (OR 3.43, 95% CI 3.29–3.58), palpitations (OR 2.51, OR 2.36–2.66), chest pain (OR 2.09, 95% CI 1.96–2.23), and confusion (OR 2.92, 95% CI 2.78–3.07). Asymptomatic infection was not associated with adverse outcomes. Vaccination was associated with reduced risk of seven symptoms. Here we describe the nature of long-COVID and the factors associated with it.
Two Rac1 pools integrate the direction and coordination of collective cell migration
Authors: Zhou Sijia , Li Peng , Liu Jiaying , Liao Juan , Li Hao , Chen Lin , Li Zhihua , Guo Qiongyu , Belguise Karine , Yi Bin , Wang Xiaobo 
Published: October 2022

AbstractIntegration of collective cell direction and coordination is believed to ensure collective guidance for efficient movement. Previous studies demonstrated that chemokine receptors PVR and EGFR govern a gradient of Rac1 activity essential for collective guidance of Drosophila border cells, whose mechanistic insight is unknown. By monitoring and manipulating subcellular Rac1 activity, here we reveal two switchable Rac1 pools at border cell protrusions and supracellular cables, two important structures responsible for direction and coordination. Rac1 and Rho1 form a positive feedback loop that guides mechanical coupling at cables to achieve migration coordination. Rac1 cooperates with Cdc42 to control protrusion growth for migration direction, as well as to regulate the protrusion-cable exchange, linking direction and coordination. PVR and EGFR guide correct Rac1 activity distribution at protrusions and cables. Therefore, our studies emphasize the existence of a balance between two Rac1 pools, rather than a Rac1 activity gradient, as an integrator for the direction and coordination of collective cell migration.
Response of soil viral communities to land use changes
Authors: Liao Hu , Li Hu , Duan Chen-Song , Zhou Xin-Yuan , Luo Qiu-Ping , An Xin-Li , Zhu Yong-Guan , Su Jian-Qiang 
Published: October 2022

AbstractSoil viruses remain understudied when compared to virus found in aquatic ecosystems. Here, we investigate the ecological patterns of soil viral communities across various land use types encompassing forest, agricultural, and urban soil in Xiamen, China. We recovered 59,626 viral operational taxonomic units (vOTUs) via size-fractioned viromic approach with additional mitomycin C treatment to induce virus release from bacterial fraction. Our results show that viral communities are significantly different amongst the land use types considered. A microdiversity analysis indicates that selection act on soil vOTUs, resulting in disparities between land use associated viral communities. Soil pH is one of the major determinants of viral community structure, associated with changes of in-silico predicted host compositions of soil vOTUs. Habitat disturbance and variation of soil moisture potentially contribute to the dynamics of putative lysogenic vOTUs. These findings provide mechanistic understandings of the ecology and evolution of soil viral communities in changing environments.
Universal dynamics of mitochondrial networks: a finite-size scaling analysis
Authors: Zamponi Nahuel , Zamponi Emiliano , Cannas Sergio A. , Chialvo Dante R. 
Published: October 2022

AbstractEvidence from models and experiments suggests that the networked structure observed in mitochondria emerges at the critical point of a phase transition controlled by fission and fusion rates. If mitochondria are poised at criticality, the relevant network quantities should scale with the system’s size. However, whether or not the expected finite-size effects take place has not been demonstrated yet. Here, we first provide a theoretical framework to interpret the scaling behavior of mitochondrial network quantities by analyzing two conceptually different models of mitochondrial dynamics. Then, we perform a finite-size scaling analysis of real mitochondrial networks extracted from microscopy images and obtain scaling exponents comparable with critical exponents from models and theory. Overall, we provide a universal description of the structural phase transition in mammalian mitochondria.
Extraction of polysaccharide from Althea rosea and its physicochemical, anti-diabetic, anti-hypertensive and antioxidant properties
Authors: Hassan Ifra , Gani Adil , Ahmad Mudasir , Banday Javid 
Published: October 2022

AbstractThe valorization of new polymer sources from underutilized plants as structuring, encapsulating, and texturizing agents for food and nutraceutical applications is gaining attention. This provides an opportunity where inexpensive plant-sourced biopolymers can play an impactful role, on both ecological and economic aspects performing equivalently effectual yet cost-effective substitutes to synthetic polymers. With this aim, we explored the use of mucilage from Althea rosea and reveal its physicochemical, in vitro antidiabetic and antihypertensive activity. Besides, structural, micrometric, crystallization, and anti-microbial properties was also seen. We determined the probable structure of the extracted mucilage by FTIR which confirmed the residues of saccharides as galactose and uronic acid with α and β configurations. It consists of 78.26% carbohydrates, 3.51% ashes, and 3.72% proteins. Here, we show that the mucilage offered protection to DNA against the oxidative damage caused by (-OH) radicals and the morphology of the mucilage particles displayed a fibrillary material settled in a net-like, tangled structure. Our results demonstrate that the reconstituted mucilage powder exhibited good water holding capacity (2.89 g water/g mucilage), solubility (27.33%), and oil holding capacity (1.79 g oil/g mucilage). Moreover, high emulsifying property (95.83%) and foaming capacity (17.04%) was noted. Our results indicate that A.rosea mucilage can potentially serve as economical and eco-friendly hydrocolloid substitute for the food and nutraceutical industry owing to its functional, hypo-lipidemic, anti-hyperglycemic, antioxidant, and anti-bacterial properties.
Treatments for hearing loss in osteogenesis imperfecta: a systematic review and meta-analysis on their efficacy
Authors: Ugarteburu Maialen , Cardoso Luis , Richter Claus-Peter , Carriero Alessandra 
Published: October 2022

AbstractAbout 70% of people with osteogenesis imperfecta (OI) experience hearing loss. There is no cure for OI, and therapies to ameliorate hearing loss rely on conventional treatments for auditory impairments in the general population. The success rate of these treatments in the OI population with poor collagenous tissues is still unclear. Here, we conduct a systematic review and meta-analysis on the efficacy of treatments addressing hearing loss in OI. This study conforms to the reporting standards of the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA). Data sources include published articles in Medline via PubMed, Web of Science, Scopus, and Embase, from their inception to November 2020. Studies included individuals with OI undergoing a hearing loss treatment, having pre- and postoperative objective assessment of hearing function at a specified follow-up length. Our search identified 1144 articles, of which 67 were reviewed at full-text screening. A random-effects meta-analysis was conducted on the selected articles (n = 12) of people with OI that underwent stapes surgery. Success was assessed as the proportion of ears with a postoperative Air–Bone Gap (ABG) ≤ 10 dB. A systematic review was conducted on the remaining articles (n = 13) reporting on other treatments. No meta-analysis was conducted on the latter due to the low number of articles on the topic and the nature of single case studies. The meta-analysis shows that stapes surgeries have a low success rate of 59.08 (95% CI 45.87 to 71.66) in the OI population. The systematic review revealed that cochlear implants, bone-anchored hearing aids, and other implantable hearing aids proved to be feasible, although challenging, in the OI population, with only 2 unsuccessful cases among the 16 reviewed single cases. This analysis of published data on OI shows poor clinical outcomes for the procedures addressing hearing loss. Further studies on hearing loss treatments for OI people are needed. Notably, the mechanisms of hearing loss in OI need to be determined to develop successful and possibly non-invasive treatment strategies.