bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validation of the Padova Prognostic Score for Colitis in Predicting Long-Term Outcome After Restorative Proctocolectomy
Authors: Angriman Imerio , Colangelo Annaclaudia , Mescoli Claudia , Fassan Matteo , D’Incà Renata , Savarino Edoardo , Pucciarelli Salvatore , Bardini Romeo , Ruffolo Cesare , Scarpa Marco 
Published: July 2022

BackgroundIn 10%–20% of cases it is impossible to make a differential diagnosis between ulcerative colitis and Crohn's colitis. A 50% failure rate of J pouch ilea-anal anastomosis is observed in Crohn's colitis. In 2009, we created the Padua Prognostic Score for Colitis (PPSC) to predict the long-term clinical and functional outcome and quality of life of patients undergoing restorative proctocolectomy with J pouch. The aim of the present study is to establish and validate the accuracy of a prognostic score for chronic inflammatory bowel diseases (IBD).Patient population and methodsThe PPSC was created in 2009 by integrating clinical and histological information of patients undergoing RPC. It included preoperative perianal abscess or fistula, rectal sparing, terminal ileum involvement, skip lesions and histological diagnosis of indeterminate colitis or Crohn's colitis on the operative specimen. The validity of this score was tested in predicting postoperative abscess or fistula, anal canal disease, pouchitis, pouch failure and new diagnosis of Crohn's disease. Correlation analysis, ROC curve analysis and survival analysis were used to validate the PPSC in a different cohort from the previous one.ResultsWe retrospectively enrolled in this study 138 consecutive patients undergoing CPR for ulcerative colitis (n = 127) or indeterminate colitis (n = 11) in our institution since 2005 to 2020. In this period, we observed 11 patients with postoperative abscess or fistula, 3 with anal canal disease, 40 with pouchitis, 6 with pouch failure and 6 with new diagnosis of Crohn's disease. In the new validation cohort, the PPSC confirmed to have a good accuracy in predicting the onset of postoperative CD (AUC = 74.5%, p = 0.018). Kaplan Meier curves demonstrate how a PPSC over 1 can reliably predicts the long-term onset of, pouchitis (p = 0.002) and anal abscess or fistulae (p = 0.04).ConclusionsIn this validation study we confirmed the accuracy of the PPSC in predicting postoperative fistulas or abscesses and pouchitis. Therefore, we believe that in clinical practice patients with a PPSC score greater than 1 should be warned of this risk of possible Crohn’s disease diagnosis and pouch failure.
Pengaruh Dana Pihak Ketiga dan Non Perfoming Loan Terhadap Penyaluran Kredit di Masa Pandemi pada BPD di Pulau Jawa
Authors: Rarassati Oktaviani , Pakpahan Rosma , Setiawan Setiawan 
Published: July 2022

This study aims to determine the effect of Third Party Funds and Non-Performing Loans during the pandemic at Regional Development Banks in Java for the 2020-2021 Period. The research method used is descriptive and uses a quantitative approach. The data used are secondary data in the form of Financial Services Authority. The number of samples used in this study were four Regional Development Banks in Java. The technique for sampling is the purposive sampling technique. The analytical technique used in this study is panel data regression analysis using the Eviews 10 program tool. Based on the results and interpretations that partically the Third Party Fund variable has a positive and significant effect to Credit Distribution and the Non-Performing variable has a negative and significant impact to Credit Distribution and Third Party Funds and Non-Performing Loans simultaneously have an effect significant to Credit Distribution.
Jurnal Perancangan Aplikasi Pencatatan Piutang Usaha bagi UMKM dalam Mendukung Efisiensi
Authors: Iman Shifa Sihatul , Tamara Destian Arshad Darulmalshah , Pratiwi Leni Nur 
Published: July 2022

Bucrak Production is one of the UMKM in Bandung City which is engaged in the production of drum musical instruments which are then sold to artists. This UMKM applies manual recording, causing the presentation of information to be slow and inaccurate. To create a business recording application and apply it to Bucrak Production. This research was carried out in stages starting from field studies, problem formulation, research objectives setting, data collection and analysis aimed at knowing the weaknesses and needs of the currently applied system. The next stage is to design the next system based on information from the previous stage, the implementation of the application that has been made will be carried out. The last stage is making conclusions. The results of this study note that there are many records in Bucrak production that need to be developed. Recording of notes which is done manually and in archiving the recording documents is not archived properly so that the information presented is not complete and accurate. The result is not being able to find out receivables per debtor that takes a long time. The application is designed in such a way that it is easy to use and is used in recording so that it can present information quickly and accurately.
Keywords:
Economía azul para un mundo de negocios sostenibles. Una revisión de literatura científica
Authors: Rojas-Díaz Pedro José , Gil-Marín Miseldra Josefina 
Published: July 2022

El actual manuscrito procura analizar la economía azul como una apuesta por un mundo de negocios sostenibles desde una revisión de literatura científica con la intención de conocer los aportes bibliográficos sobre el tema. De tipo descriptiva documental. La economía azul es un término generado en los últimos años como alternativa al modelo de explotación económico de la naturaleza, procura sostenibilidad en el tiempo, desarrollándose con mayor énfasis en el sector marítimo, se refiere en brindar alternativas sostenibles de negocio, especialmente del carbono azul (el carbono almacenado en los ecosistemas de manglares, pastos marinos y marismas, que volverá a), nuevos productos acuícolas, energía renovable marina (que a su vez incluye energía eólica, undimotriz y mareomotriz), bioproductos (farmacéuticos y agroquímicos); sin embargo, la economía azul a nivel marítimo, viene a representar un conflicto de intereses en áreas tradicionales como el petróleo, gas; en Latinoamérica resulta muy limitada su aplicación.
ANALISIS PEMAHAMAN KONSEP SISWA PADA MATERI PELUANG DITINJAU DARI TEORI APOS PADA SISWA SMP KELAS VIII
Authors: Nailopo Elfrida , Fitriani Fitriani , Simarmata Justin Eduardo 
Published: July 2022

Penelitian ini bertujuan untuk menganalisis pemahaman konsep siswa pada materi peluang ditinjau dari teori APOS. Jenis penelitian ini menggunakan penelitian deskriptif kualitatif. Subjek penelitian adalah siswa kelas VIII SMP Satap Negeri Nakol yang berjumlah 15 siswa. Teknik pengumpulan data dilakukan dengan tes dan wawancara. Wawancara dilakukan secara mendalam kepada 3 subjek penelitian yang terdiri dari 1 subjek berkemampuan tinggi, 1 subjek berkemampuan sedang, dan 1 subjek berkempuan rendah. Berdasarkan hasil yang diperoleh bahwa tingkat pemahaman konsep siswa berada pada tingkatan yang berbeda. Siswa belum mampu menggunakan konsep matematika dengan baik dalam menyelesaikan masalah berkaitan dengan soal peluang. Selain itu, siswa belum mampu menyajikan alternatif jawaban yang lain dari permasalahan yang diberikan. Maka dari itu, teori APOS digunakan untuk mengamati sejauh mana pencapaian konsep siswa terhadap matematika pada materi peluang ditinjau dari rangkaian aksi, proses, objek, dan skema
AN ANALYSIS OF STUDENTS’ READING COMPREHENSION ACHIEVEMENT AT SECOND SEMESTER STUDENTS OF BHINNEKA PGRI UNIVERSITY IN THE ACADEMIC YEAR 2020/2021
Authors: Agustin Nining Ayuk 
Published: July 2022

To reading comprehension, especially long texts in foreign languages, some students have problems, such as being lazy and bored. If this problem persists, it will affect student achievement. This study was conducted with the aim of (1) to find how is the students’ reading comprehension achievement at second semester of Bhinneka PGRI University in the academic year 2020/2021. (2) to find what are the factors that affect the students’ reading comprehension achievement at second semester students of Bhinneka PGRI University in the academic year 2020/2021. The study used qualitative research to obtain valid data from 25 participants in class A at second semester in English Depatment. Researchers obtained data on reading comprehension test scores from the results of the TOEFL test questions given by researchers with an average value of 62. To test the truth, the researchers conducted interviews and questionnaire data. The results of the analysis are also through interviews with teachers and students, as well as questionnaires answered by students. It was concluded that learning reading skills in the second semester TOEFL test in English Depatment at the University of Bhinneka PGRI in the 2020/2021 academic year got poor achievements. Because they experience several problems in learning, namely difficulty in accessing the internet, lack of vocabulary that students have, and the material obtained are difficult to capture.
Pelatihan Aplikasi Berbasis Teknologi pada Guru-Guru di Yayasan Nurul Hikmah Al Hakim
Authors: Rahmayanti Indah , Qura Ummul , Putra Gilang Kumari 
Published: July 2022

Pendekatan berbasis teknologi sangat penting dewasa ini, terutama dalam hal penyampaian pesan, ide dan gagasan, karena memiliki daya tarik tinggi, atraktif dan mudah dipahami peserta didik dalam pembelajaran daring. Yayasan Nurul Hikmah AL-Hakim sebagai Lembaga penyelenggara Pendidikan SMP, SMA, SMK dapat memanfaatkan kebermanfaatan pelatihan ini sebagai optimalisasi kemampuan liveworksheet yang mumpuni kepada peserta didiknya. Oleh sebab itu tim pengabdian masyarakat Universitas Muhammadiyah Prof DR HAMKA berinisiatif melaksanakan pengabdian kepada masyarakat berupa pelatihan berbasis teknologi dengan menerapkan pembelajaran melalui liveworksheet kepada guru-guru di Yayasan Nurul Hikmah AL-Hakim, Jonggol, Jawa Barat. Kegiatan ini dilaksanakan dalam bentuk pemberian ceramah materi teori, praktikum dan penugasan pengaplikasian langsung liveworksheet sebagai teacher dan student pada aplikasinya. Secara umum, pelaksanaan PKM berjalan lancar tanpa terkendala apapun,karena dukungan dari pihak yayasan. Hasil luaran kegiatan PKM ini adalah karya guru-guru dalam menerapkan pembelajaran liveworksheet yang memiliki kualitas cukup baik bila mempertimbangkan keterbatasan kemampuan dan waktu pengerjaan. Hal ini karena antusiasme dan kreativitas guru-guru Yayasan Nurul Hikmah AL Hakim yang tinggi sehingga mampu menyelesaikan tugas dengan baik
Pengaruh Penguasaan Mata Kuliah Klasifikasi DDC terhadap Kemampuan Menentukan Notasi
Authors: Afifah Nur 
Published: July 2022

This study aims to determine how the mastery of the DDC classification subject has on the abilities of the students of the 2017-2019 Library Science study program in determining the DDC notation. This study took a sample of 99 students of the Library Science study program at UIN Raden Fatah Palembang in 2017-2019. The type of research used is descriptive quantitative. Methods of data collection in this study in the form of questionnaires and documentation.The data processing technique in this research is to analyze the data using the grand mean formula. The results of the analysis show that the average total score of mastery of DDC classification courses is 0.61 which can be categorized as high because it is in the 0.60-0.80 interval. Meanwhile, the ability to determine notation is also known by performing calculations using the grand mean formula, the results show that the average total value of the ability to determine notation is 0.62 which can be categorized as high because it is in the 0.60-0.80 interval. Furthermore, based on the analysis using simple linear regression, the result of the coefficient of determination (R2) of 0.807 or 80.7% the ability to determine notation is influenced by the mastery of the DDC classification course and based on the results of hypothesis testing that it is known that the hypothesis or H1 is accepted because tcount ttable (20,113 1.66071) which states that there is an influence of mastery of the DDC classification course on the ability to determine notation.
PELATIHAN MEMBUAT MEDIA PEMBELAJARAN BERBASIS IT BAGI GURU-GURU SMP DAARUL FAALAH CISAAT KABUPATEN SUKABUMI
Authors: Maharani Isma Nastiti , Saepuloh Luthpi 
Published: July 2022

ABSTRAKKebutuhan akan peningkatan kualitas guru-guru merupakan hal yang wajib dilakukan oleh satuan pendidikan. SMP Daarul Faalah berinisiatif untuk meningkatkan keterampilan gurur-guru terutama dalam pembuatan media pembelajaran berbasis teknologi informasi. Tujuannya terjadi peningkatan proses dan hasil pembelajaran yang berkualitas di sekolah. Tim pelaksana pengabdian kepada masyarakat diminta untuk melakukan pendampingan dalam kegiatan peningkatan keterampilan guru-guru SMP Daarul Faalah Cisaat dalam hal membuat media pembelajaran berbasis teknologi informasi. Program pelatihan ini dapat memenuhi kebutuhan masyarakat (guru) di lingkup SMP Daarul Faalah dalam rangka peningkatan kualitas guru-guru di SMP Daarul Faalah, khususnya dalam pembuatan media pembelajaran berbasis teknologi informasi. Program pelatihan ini juga dilakukan dalam rangka mensukseskan program pemerintah bagi guru-guru agar mereka melek teknologi dan menerapkannya dalam proses pembelajaran yang berujung pada efektivitas pencapaian tujuan pembelajaran.
The Relationship between CC Ligand 5 Plasma Levels and Modic Changes in Low Back Pain Patients’ Severity
Authors: Krinseani Firstisa Nuzulia , Syarif Indra  , Hendra Permana  
Published: July 2022

Background: Low back pain (LBP) is one of the global health problems. The most common cause of LBP is disc degeneration. Modic changes (MC) are the most common MRI features in patients with disc degeneration. As a result of cartilage and disc tissue damage, CCL 5 is released and modulates pain responses in the dorsal root ganglion. This study aims to determine the relationship between CCL5 levels and the description of Modic changes on MRI with pain levels in patients with low back pain.
Methods: This study is a cross-sectional study. The research subjects were LBP patients who were treated at the Neurology Polyclinic, Dr. M. Djamil General Hospital, Padang, in the range of March 2021-December 2021, who meets the inclusion and exclusion criteria. Subjects will be taken blood to assess CCL5 plasma levels, pain assessment using the McGill Pain Questionnaire, and undergo an MRI examination.
Results: A total of 52 subjects consisted of 23 men and 29 women with an age range of 34-77 years. Most of the Modic changes were found in the type 2 group. Based on the pain scale, there were two groups with mild pain and moderate pain. On examination of plasma CCL 5 levels, the median value of plasma CCL5 levels was 303,271 ng/L. There was a significant relationship between plasma CCL5 levels and pain levels in patients with low back pain (p = 0.004). There was no significant relationship between Modic changes and the severity of pain.
Conclusion: Plasma CCL5 levels are associated with pain levels in patients with low back pain, while Modic changes are not associated with pain severity.
Pengaruh Inovasi Ojek Menjadi Ojek Online Pada Ekonomi Kreatif Di Era Revolusi Industri 4.0
Authors: Crystrie Dhara Ayu , Adhianur Syarifa 
Published: July 2022

Perkembangan teknologi yang semakin canggih memberikan dampak perubahan pada aktivitas dan pola hidup manusia. Segala sesuatu yang berebasis teknologi kecanggihan dan otomatisasi menjadikan suatu kenyamanan bagi manusia dalam memenuhi kebutuhan hidupnya. Teknologi berkembang, ilmu pengetahuan juga ikut berkembang dengan demikian dapat melahirkan sumber daya manusia yang unggul, yang dapat menciptakan inovasi dalam ekonomi kreatif. Seperti munculnya inovasi baru pada bidang transporasi berupa ojek online. Kehadiran ojek online ini cukup menarik minat masyarakat untuk menggunakannya, karena dengan adanya ojek online memberikan banyak kemudahan untuk menjalankan aktivitasnya. Kehadiran ojek online ini memberikan banyak penawaran selain jasa antar, memberikan pelayanan lainnya yang lebih praktis, efektif dan efisien, sehingga bisa menarik minat konsumen. Bentuk inovasi ojek online ini hadir dengan beberapa perusahaan yang memiliki ciri sendiri baik dalam pelayanan atau kekreativitasan dari perusahaan tersebut. Penelitian ini dilkaukan menggunakan metode kuantitatif dengan pendekatan deskriptif dengan metode survey kepada pengguna atau pelanggadengan ojek online seperti Gojek, Grab dan Maxim. Hasil dari penelitian ini menunjukan bahwa Pengaruh Inovasi Ojek Menjadi Ojek online pada ekonomi kreatif di era revolusi 4.0 ini memiliki dampak bagi masyarakat khususnya masyarakat Tasikmalaya.
OmniUV: A Multipurpose Simulation Toolkit for VLBI Observation
Authors: Liu Lei , Zheng Weimin , Fu Jian , Xu Zhijun 
Published: July 2022

Abstract
We present OmniUV, a multipurpose simulation toolkit for space and ground VLBI observations. It supports various kinds of VLBI stations, including Earth (ground) fixed, Earth orbit, Lunar fixed, Lunar orbit, Moon–Earth, and Earth–Sun Lagrange 1 and 2 points, etc. The main functionalities of this toolkit are: (1) trajectory calculation; (2) baseline uv calculation, by taking the availability of each station into account; (3) visibility simulation for the given uv distribution, source structure, and system noise; (4) image and beam reconstruction. Two scenarios, namely the space VLBI network and the wide-field array, are presented as the application of the toolkit at completely different scales. OmniUV is the acronym of “Omnipotent UV.” We hope it could work as a general framework, in which various kinds of stations could be easily incorporated and the functionalities could be further extended. The toolkit has been made publicly available.
Crise, lien et engagement social de la jeunesse bruxelloise à l’ère de la COVID-19
Authors: Mandjombe Robert , Boukezoula Inès , Gillet François 
Published: July 2022

Puisant sa sève des observations relevées et enquêtes menées auprès des jeunes lors du premier confinement à Bruxelles, le présent article vise à rendre compte des rapports entretenus entre la crise, le lien social et la jeunesse bruxelloise face à la pandémie de la COVID-19. Entre disqualification au sein des familles et désaffiliation avec l’institution scolaire, ce développement donne à voir comment les rapports à l’altérité ainsi que les formes de sociabilité et d’individualisation se redessinent chez les jeunes bruxellois issus des quartiers dits « populaires » à mesure qu’évolue la crise sanitaire. L’article tend également à comprendre comment la crise, malgré ses multiples acceptions et sa longue trajectoire historique, est aujourd’hui, contre toute attente, une opportunité sociographique de relever à la fois des formes de coopération, de maintien du lien et d’engagement social chez les jeunes dans les quartiers « populaires » de la capitale belge.
Immunogenicity Assessment of Antileukemic Agent Glutaminase from Escherichia coli, Pseudomonas sp., and Bacillus sp.
Authors: Parmar Jyotsna , Tripathi Shikha , Kumar Awanish 
Published: July 2022

Background:
L-glutaminase (L-glutaminase or glutamine amidohydrolase: EC 3.5.1.2) is an antileukemic agent which catalyzes the deamidation of glutamine to glutamic acid and ammonia. It is a highly potent antitumor drug solely or in combination with L-asparaginase. In the market, various microbial glutaminases are available, which are used in treatment. The high immunogenicity was reported with microbial glutaminase when they are introduced in the body during the treatment of acute lymphoblastic leukemia (ALL).

Methods:
This study was aimed to determine the immunogenicity of the less studied enzyme L-glutaminase from Escherichia coli, Pseudomonas sp., and Bacillus sp. to reduce the allergenicity caused by this enzyme. In the present study, we determined the immunogenicity and allergenicity of microbial glutaminase using an immunoinformatics approach to predict immunogenic and allergenic epitopes with their structural analysis also.

Results:
We found high immunogenicity of glutaminase from these three microbial sources but did not find a significant difference in their immunogenicity, while E. coli glutaminase showed a high relative frequency of allergenic epitopes.

Conclusions:
In our knowledge, this is the first research report that presented the immunogenic epitopes and structural allergenic determinants that warrant further work to minimize the immune response of glutaminase and could contribute to reducing the side effect and hypersensitivity response of glutaminase during the treatment.
Antibacterial and Antibiofilm Properties of Azadirachta indica (Neem), Aloe vera (Aloe vera), and Mentha piperita (Peppermint) against Multidrug-Resistant Clinical Isolates
Authors: Mehrishi Priya , Agarwal Priti , Broor Shobha , Sharma Amisha 
Published: July 2022

Background:
Misuse of antibiotics globally has resulted in the development of resistant bacterial strains. One of the sole reasons for bacteria being resistant to antibiotics is the production of biofilm. Biofilms are microbial communities which get adhere to solid surfaces easily and pose an important virulence factor for causing many chronic infections. Therefore, there is an urge to find out new potential sources which can be used as an alternative to the existing antibiotics.

Methods:
The present study was conducted on three medicinal plant extracts Azadirachta indica, Aloe vera, and Mentha piperita to assess their antibacterial and antibiofilm properties against 58 multidrug-resistant clinical isolates using agar well diffusion method, minimum bactericidal concentration (MBC), and crystal violet modified assay at 50, 25, 12.5, and 6.25 mg/ml concentration.

Results:

A. indica showed a maximum zone of inhibition of (17.8 ± 1.52 mm) and (18.1 ± 1.45 mm) at 50 and 25 mg/ml concentration. Biofilm inhibition was more than 80% for Staphylococcus aureus and Pseudomonas aeruginosa and MBC came out to be 6.25 ± 2.96–6.25 ± 4.91 mg/ml (mean range). A. vera showed the highest zone of inhibition for S. aureus (18.2 ± 1.48 mm) at 50 mg/ml concentration followed by Staphylococcus saprophyticus (17.8 ± 1.48 mm) and Staphylococcus epidermidis (18.0 ± 1.60 mm). Biofilm inhibition was seen more than 50% and MBC was 50 ± 23.14–50 ± 25.72 mg/ml (mean range).

Conclusion:
All the three plant extracts were effective, but A. indica and A. vera were found to be more potent than M. piperita.