bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of cerebral vasospasm following traumatic intracranial hemorrhage: incidence, risk factors, and clinical outcomes
Authors: Dicpinigaitis Alis J. , Feldstein Eric , Damodara Nitesh , Cooper Jared B. , Shapiro Steven D. , Kamal Haris , Kinon Merritt D. , Pisapia Jared , Rosenberg Jon , Gandhi Chirag D. , Al-Mufti Fawaz 
Published: March 2022

OBJECTIVE
Limited evidence exists characterizing the incidence, risk factors, and clinical associations of cerebral vasospasm following traumatic intracranial hemorrhage (tICH) on a large scale. Therefore, the authors sought to use data from a national inpatient registry to investigate these aspects of posttraumatic vasospasm (PTV) to further elucidate potential causes of neurological morbidity and mortality subsequent to the initial insult.

METHODS
Weighted discharge data from the National (Nationwide) Inpatient Sample from 2015 to 2018 were queried to identify patients with tICH who underwent diagnostic angiography in the same admission and, subsequently, those who developed angiographically confirmed cerebral vasospasm. Multivariable logistic regression analysis was performed to identify significant associations between clinical covariates and the development of vasospasm, and a tICH vasospasm predictive model (tICH-VPM) was generated based on the effect sizes of these parameters.

RESULTS
Among 5880 identified patients with tICH, 375 developed PTV corresponding to an incidence of 6.4%. Multivariable adjusted modeling determined that the following clinical covariates were independently associated with the development of PTV, among others: age (adjusted odds ratio [aOR] 0.98, 95% CI 0.97–0.99; p < 0.001), admission Glasgow Coma Scale score < 9 (aOR 1.80, 95% CI 1.12–2.90; p = 0.015), intraventricular hemorrhage (aOR 6.27, 95% CI 3.49–11.26; p < 0.001), tobacco smoking (aOR 1.36, 95% CI 1.02–1.80; p = 0.035), cocaine use (aOR 3.62, 95% CI 1.97–6.63; p < 0.001), fever (aOR 2.09, 95% CI 1.34–3.27; p = 0.001), and hypokalemia (aOR 1.62, 95% CI 1.26–2.08; p < 0.001). The tICH-VPM achieved moderately high discrimination, with an area under the curve of 0.75 (sensitivity = 0.61 and specificity = 0.81). Development of vasospasm was independently associated with a lower likelihood of routine discharge (aOR 0.60, 95% CI 0.45–0.78; p < 0.001) and an extended hospital length of stay (aOR 3.53, 95% CI 2.78–4.48; p < 0.001), but not with mortality.

CONCLUSIONS
This population-based analysis of vasospasm in tICH has identified common clinical risk factors for its development, and has established an independent association between the development of vasospasm and poorer neurological outcomes.
Pengaruh Kebijakan Pembelajaran pada Masa Pandemi Covid-19 terhadap Efikasi Diri dan Perilaku Belajar Siswa
Authors: Suryono Suryono , Bastian Adolf , Oemar Fahmi 
Published: February 2022

Kebijakan pembelajaran pada masa pandemi berbeda dengan keadaan normal. Efikasi diri dan perilaku belajar siswa pun juga sangat berbeda. Kedua poin ini sangat menarik untuk dikaji mendalam. Dalam penelitian ini, tujuan penelitian ini untuk menganalisis pengaruh kebijakan pembelajaran terhadap efikasi diri dan perilaku belajar siswa. Penelitian ini menggunakan pendekatan kuantitatif dengan metode survei. Sampel yang digunakan adalah 89 siswa SMKN 1 Riau. Pengambilan sampel dilakukan secara acak sederhana. Data penelitian diperoleh melalui penyebaran kuesioner dan dianalisis dengan menggunakan analisis jalur (path analysis) yang didukung analisis statistik deskriptif. Hasil penelitian ini menunjukkan bahwa kebijakan pembelajaran berpengaruh langsung terhadap perilaku belajar, efikasi diri berpengaruh langsung positif dan sangat signifikan terhadap perilaku belajar, dan kebijakan pembelajaran berpengaruh langsung positif dan sangat signifikan terhadap efikasi diri. Selain itu, kebijakan pembelajaran berpengaruh tidak langsung positif dan sangat signifikan terhadap perilaku belajar dengan mediasi efikasi diri. Oleh karena itu, perbaikan kebijakan pembelajaran dapat meningkatkan efikasi diri dan perilaku belajar siswa, sehingga pimpinan sekolah perlu menyesuaikan kebijakan pembelajaran sesuai kebutuhan dan kondisi aktual internal dan eksternal sekolah. Selain itu, efikasi diri siswa juga perlu ditingkatkan secara berkelanjutan melalui berbagai penguatan, misalnya supervisi, konseling, dan pemberian reward bagi siswa yang berprestasi. Demikian pula penelitian lanjutan sebagai konsekuensi teoretik hasil penelitian juga perlu dilakukan dengan sampel berbeda dengan jumlah lebih besar serta menggunakan teknik analisis yang berbeda, misalnya stuctutral equation modeling (SEM).
Analisis Perilaku Penumpang Krl Commuter Line Solo Balapan – Yogyakarta Di Masa Pandemi Dan Pengaruhnya Terhadap Pola Perjalanan DAN PENGARUHNYA TERHADAP POLA PERJALANAN
Authors: Indriani Tri Safira , Sodikin Sodikin , Pristyawati Tantin 
Published: February 2022

KRL Commuter Line merupakan transportasi pilihan yang ramai diminati oleh masyarakat kota Solo Balapan – Yogyakarta sejak beroperasi Februari 2021. Beroperasinya KRL ditengah masa pandemi ini membuat pihak PT KAI menetapkan kebijakan yang lebih ketat dalam menerapkan protokol kesehatan guna memutus mata rantai penyebaran covid-19. Penelitian ini dilakukan untuk mengetahui pengaruh perilaku penumpang terhadap pola perjalanan serta mengetahui pengaruh kebijakan yang direalisasikan oleh petugas operator KRL pada pola perjalanan. Teknik pengambilan data menggunakan kuesioner yang dibagikan secara online, kemudian diolah menggunakan Microsoft Excel dan SPSS (Statistical Product and Service Solution). Teknik analisis yang digunakan adalah analisis regresi linear berganda. Hasil penelitian secara parsial menunjukkan bahwa t hitung (1,280) < t tabel (1,985), sehingga H1 ditolak atau tidak berpengaruh terhadap pola perjalanan. Sedangkan secara simultan menunjukkan bahwa variabel perilaku penumpang (X1) dan pandemi (X2) berpengaruh terhadap pola perjalanan penumpang KRL (Y) secara simultan sebesar 0,000 yang artinya sig < 0,05. Dan nilai f hitung (17,787) > f tabel (3,09). Yang artinya apabila kebijakan yang direalisasikan optimal serta penumpang mematuhi kebijakan tersebut maka keamanan dan kenyamanan yang dirasakan penumpang juga akan maksimal. Persentase pengaruh kedua variabel tersebut sebesar 25,1% yang dihitung melalui uji koefisien determinasi.
Aplikasi Value Engineering Terhadap Struktur Plat Lantai Menggunakan Desain Half Slab Precast Pembangunan Gedung Kedokteran Nuklir Dan Radioterapi RSUD Dr. Moewardi
Authors: Rachmawati Agustina , Safarizki Hendramawat Aski , Marwahyudi Marwahyudi 
Published: February 2022

Perencanaan pembangunan Gedung Kedokteran Nuklir dan Radioterapi RSUD Dr. Moewardi tahun 2017 merupakan upaya peningkatan sarana dan prasarana dalam Pelayanan Unggulan Onkologi Terpadu. Pelaksanaan pembangunan dilakukan secara bertahap. Tahap I dilaksanakan pada tahun 2018, Tahap II dilaksanakan pada tahun 2019 dan Tahap III tahun 2020. Value Engineering diperlukan untuk merubah suatu item pekerjaan dengan bobot volume yang besar dengan item yang lebih sederhana pelaksanaanya tanpa mengurangi mutu dan fungsi dari nilai kegunaannya. Dalam proyek ini, plat lantai dapat diganti menggunakan half slab precast dan diharapkan terdapat suatu peningkatan didalamnya, bisa dari penghematan biaya atau kinerja pelaksanaannya. Hasil dalam penelitian ini diperoleh cost/worth sebesar 1,13 > 1 adanya penghematan walau tidak signifikan. Biaya pelaksanaan awal sebesar Rp 3.191.767.746,- dan usulan biaya pelaksanaan alternatif sebesar Rp2.819.500.274,67,- sehingga mendapat penghematan biaya sebesar Rp 372.267.471,- atau sebesar 11,66%.
Aesthetics of Byzantine Christian Art
Authors: AL-AKAM RUAA SADEQ MHMOOD , Rasheed Salam Hameed 
Published: February 2022

The current study addressed the study of (The aesthetics of Byzantine Christian art). Its problem was identified by answering the following question: What are the aesthetics of Christian art represented by the Byzantine icon? Also, it aims to (recognize the aesthetics of Byzantine icon art). The research community was identified to achieve the goal, which consisted of icons and religious drawings that the researchers could count as a framework for the research community after collecting pictures of the subject from foreign and Arab sources and Internet sites. The sample was drawn according to the following reasons: a) It covers the temporal and spatial limits of the research and what fits with the data to achieve the goal, b) Diversity of technical methods adopted in drawing icons and c) The study sample models witnessed a diversity of contents and ideas. The research study reached the following conclusions. First, they borrow iconographic products, religious images and semantic symbols related to the Christian tradition and employ them through analytical visual inferences, in harmony with the structural and structural treatments of the elements and organizational foundations. Second, the products of icon art are associated with the nature of the transition from the tangible to the ideal and in line with the loading of the composition structure with an expressive energy, explaining the necessity of interpretation of religious discourse, and defining the operational vision with a clear dramatic sense. Third, the iconographic models depend on philosophical data supporting the religious meaning carried in them and giving endless explanations for the public discourse affecting the functionality of (idea) or (event). Fourth, the models of iconographic art are close to the nature of the functional induction of spiritual and sacred tendencies. At the level of deep interpretations accompanying visual forms with a clear aesthetic impact, we find that icon art carries with it religious reference effects related to the sacred. Lastly, Icon art invests in accumulating aesthetic knowledge to produce the artistic image and summons the largest possible amount of data affecting its formulation and output.
Determinan Perilaku Pernikahan Dini Berdasarkan Perspektif Kesehatan Reproduksi Aman dan Fiqih Islam
Authors: Ilmiah Widia Shofa , Azizah Fifin Maulidatul , Hikmawati Nova 
Published: March 2022

AbstrakPernikahan dini masih menjadi permasalahan kependudukan dan kesehatan reproduksi perempuan global. Data pernikahan dini dunia tahun 2015 (142 juta), di Indonesia tahun 2013 (2.6%) menikah umur <15 tahun, 23.9% menikah umur 15-19 tahun, tahun 2018 (1,5 juta) menikah <17 tahun; di Jawa Timur tahun 2015 (8.99%), tahun 2016 (21.16%), di Kabupaten Probolinggo tahun 2015 (21.02%), tahun 2016 (41.18%), hasil studi pendahuluan di Desa Patalan Wonomerto kepada 10 ibu diketahui 7 ibu (70%) Â menikah umur <17 tahun. Tujuan penelitian menganalisis determinan paling dominan mempengaruhi perilaku pernikahan dini berdasarkan perspektif kesehatan reproduksi aman dan fiqih islam. Penelitian desain analitik korelasi dengan pendekatan cross sectional, populasi seluruh ibu yang memiliki anak remaja di Wonomerto 45 orang, sampel 40 orang, teknik simple random sampling, instrumen kuesioner, uji statistik multiple regresi logistik. Hasil penelitian tingkat pendidikan p 0.999 > Î± 0.05; sikap responden p 0.365 > Î± 0.05; tingkat pengetahuan p 0.006 dengan nilai 1/PR = 52.632 dan niat p 0.012 dengan nilai 1/Prevalence Ratio (1/PR) = 40.000. Kesimpulan bahwa tingkat pengetahuan memiliki pengaruh 52 kali terhadap perilaku pernikahan dini. Oleh karena itu, penting bagi bidan sebagai garda terdepan untuk memberikan KIE setiap melakukan pelayanan terkait kesehatan reproduksi remaja..Kata kunci : determinan, pernikahan dini, kesehatan reproduksi, fiqih islamÂ AbstractEarly marriage is still a global women's population and reproductive health problem. Data on early marriage in the world in 2015 (142 million), Indonesia in 2013 (2.6%) married <15 y.o, and 23.9% married on 15-19 y.o, in 2018 (1.5 million) married < 17 y.o; in East Java in 2015 (8.99%), in 2016 (21.16%), in Probolinggo Regency in 2015 (21.02%), in 2016 (41.18%), the preliminary study in Patalan Wonomerto to 10 mothers found 7 mothers (70%) were married < 17 y.o. The purpose to analyze the most dominant determinants affecting early marriage behavior based on perspective of safe reproductive health and Islamic jurisprudence. This study a correlation analytic design a cross-sectional, population of 45 mothers with adolescent children in Wonomerto, sample were 40 people; simple random sampling, questionnaires, multiple logistic regression. The results that the level of education (p 0.999 > 0.05), attitude (p 0.365 > 0.05), level of knowledge p 0.006 with (1/PR) = 52.632; intention p 0.012, (1/PR) = 40,000. The conclusion that the level of knowledge has an effect of 52 times on early marriage behavior. It is important for midwives as the front line to provide IEC every time at provide services related to adolescent reproductive health.Â Keywords: determinant, early marriage, health reproduction, fiqih IslamÂ
Vaginal Secretion Epithelium Count as a Prognostic Indicator of High Abundance of Ureaplasmas in Women with a Normal Nugent Score
Authors: Biernat-Sudolska Małgorzata , Talaga-Ćwiertnia Katarzyna , Gajda Paulina 
Published: February 2022

Abstract
Genital tract ureaplasma infections are associated with numerous complications, ranging from inflammation, through infertility, to problematic pregnancy. In the course of ureaplasma infection, the risk of human papillomavirus infection increases. Diagnostic tests for urea-plasma infections are not always carried out, especially in women with the normal Nugent test results. The study attempts to check whether it is possible to find a prognostic indicator that could suggest a high abundance of ureaplasmas (≥ 104 CFU/ml) at the stage of the initial examination of vaginal discharge. Such a prognostic factor could qualify women for further tests to detect infections with these atypical bacteria. Six hundred twenty-seven white women with a score of 0–3 on the Nugent scale were tested, including 322 patients with a high abundance of ureaplasmas (≥ 104 CFU/ml) and 305 who tested negative for these bacteria. Ureaplasma infections were detected statistically significant in women who had few or no epithelial cells in the genital swab specimens compared to the results obtained for women with numerous or very numerous epithelial cells (p < 0.001). The risk of the high density of ureaplasmas was 38.7% higher with fewer or no epithelial cells than with high numbers. In patients aged 18–40 years with few or no epithelial cells, a high density of ureaplasmas (≥ 104 CFU/ml) was observed significantly more frequently (p = 0.003). Determining the number of epithelial cells in Gram-stained slides may be the prognostic indicator of ureaplasma infection. Testing for genital ureaplasma infection should be considered, especially in women of childbearing age (18–40 years), even if the Nugent test value is normal and pH ≤ 4.6.
The Relation Between Host TLR9 -1486T/C, rs187084 Gene Polymorphisms and Helicobacter pylori cagA, sodB, hsp60, and vacA Virulence Genes among Gastric Cancer Patients
Authors: Sultan Amira M. , Shenouda Ragy , Sultan Ahmad M. , Shehta Ahmed , Nabiel Yasmin 
Published: February 2022

Abstract
To identify the associations between different genotypes of TLR9 -1486T/C (rs187084) with gastric cancer patients and reveal their relation to Helicobacter pylori virulence genes (cagA, sodB, hsp60 and vacA). Patients with gastric cancer were recruited to our study, diagnosed both endoscopically and histopathologically. H. pylori were isolated from gastric samples by culture and PCR amplification of the glmM gene. Virulence genes cagA, sodB, hsp60, and vacA were detected by multiplex PCR. Blood samples were used for genotyping of TLR9 -1486T/C (rs187084) by PCR-RFLP. Out of 132 patients with gastric cancer, 106 (80.3%) were positive for H. pylori. A similar number of healthy participants was recruited as controls. The prevalence of cagA, sodB, hsp60, and vacA genes among H. pylori was 90.6%, 70.8%, 83.0%, and 95.3%, respectively. The vacA gene alleles had a prevalence of 95.3% for vacAs1/s2, 52.8% for vacAm1, and 42.5% for vacAm2. The CC genotype of TLR9 -1486T/C had a significantly higher frequency in gastric cancer patients when compared to healthy participants (p = 0.045). Furthermore, the CC genotype demonstrated a significant association with H. pylori strains carrying sodB, hsp60, and vacAm1 virulence genes (p = 0.021, p = 0.049, and p = 0.048 respectively). Patients with CC genotype of TLR9 -1486T/C (rs187084) might be at higher risk for the development of gastric cancer, and its co-existence with H. pylori strains carrying sodB, hsp60, or vacAm1 virulence genes might have a synergistic effect in the development of gastric cancer. Further studies on a wider scale are recommended.
Helicobacter pylori and Epstein-Barr Virus Co-Infection in Polish Patients with Gastric Cancer – A Pilot Study
Authors: Dzikowiec Magdalena , Lik Przemysław , Kiszałkiewicz Justyna , Kuczyńska Aleksandra , Mordalski Marek , Nejc Dariusz , Piekarski Janusz , Brzeziańska-Lasota Ewa , Pastuszak-Lewandoska Dorota 
Published: February 2022

Abstract
The infectious agents may be the etiological factor of up to 15–20% of cancers. In stomach cancer, attention is paid to Helicobacter pylori and Epstein-Barr virus, both of which cause gastritis and can lead to tumor development. In co-infection, the inflammatory process is much more intense. We assessed the seroprevalence towards H. pylori and EBV in 32 patients with diagnosed gastric cancer. H. pylori antibodies were found in 69% patients, and anti-EBV – in all of them. The study confirmed that co-infection of H. pylori and EBV seems to be important in etiopathology of gastric cancer.
Detection by Whole-Genome Sequencing of a Novel Metallo-β-Lactamase Produced by Wautersiella falsenii Causing Urinary Tract Infection in Tunisia
Authors: Maaroufi Raouaa , Dziri Olfa , Hadjadj Linda , Diene Seydina M. , Rolain Jean-Marc , Chouchani Chedly 
Published: February 2022

Abstract

Wautersiella falsenii is a rarely non-fermenting Gram-negative bacterium and belongs to the Flavobacteriaceae family. This nosocomial pathogen can cause several human infections, especially among immunocompromised patients. Here, we describe the whole genome sequence of a clinical W. falsenii strain isolated from a urine sample of a 35-year-old woman with a urinary tract infection in Tunisia. We investigated its phenotype and genotype.
After bacterial identification by the MALDI-TOF method, the whole-genome sequencing of this strain was performed. This isolate was not susceptible to various antibiotics, including β-lactams, aminoglycosides, and quinolones. However, it remains susceptible to imipenem (MIC = 0.25 mg/l), ertapenem (MIC = 0.75 mg/l), and meropenem (MIC = 0.19 mg/l). Interestingly, the E-TEST® (MP/MPI) showed a reduced MIC of meropenem +/− EDTA (0.064 μg/ml). Besides, the color change from yellow to red in the β CARBA test only after 24 hours of incubation can be interpreted in two ways. On the one hand, as a likely low expression of the gene encoding metallo-β-lactamase. On the other hand, and more likely, it may be a false-positive result because, according to the test manufacturer's recommendations, the test should be read after 30 minutes. Perhaps, therefore, this gene is not expressed in the tested strain. Moreover, the whole-genome sequence analysis demonstrated the presence of a novel chromosomally located subclass B1 metallo-β-lactamase EBR-like enzyme, sharing 94.92% amino acid identity with a previously described carbapenemase produced by Empedobacter brevis, EBR-1. The results also showed the detection of other antibiotic resistance genes and the absence of plasmids. So far, this study is the first report on the detection of W. falsenii in Tunisia. These findings prove that W. falsenii could be a potential reservoir of antibiotic resistance genes, e.g., β-lactamases. Collaborative efforts and effective hygiene measures should be established to prevent the emergence of this species in our health care settings.
Atuação do enfermeiro frente a qualidade de vida de mulheres climatéricas com incontinência urinária: revisão integrativa da literatura
Authors: Andrade Ângela Roberta Lessa de , Pontes Alice Fonseca , Silva Filho Jabiael Carneiro da , Santos Isabel Cristina Ramos Vieira 
Published: February 2022

Objetivou-se a identificação da IU como fator associado à diminuição da QV em mulheres climatéricas, e tornou-se relevante subsidiar as estratégias que visem à promoção da saúde, o alívio dos sintomas, à prevenção e controle da IU. E desta forma, melhorar a QV destas mulheres com uma abordagem inclusiva, holística e humanizada. A amostra final desta revisão foi formada por nove artigos datados entre os anos de 1998 e 2021. Na seleção dos materiais utilizados encontram-se os resultados obtidos na caracterização da produção científica sobre as formas de avaliação da força da musculatura do assoalho pélvico e técnicas de fortalecimento deste, em mulheres com IU. A atual revisão demonstrou que as publicações realizadas nesta área, e principalmente por Enfermeiros, ainda tem pouca representatividade, e que devido à relevância do tema precisamos desenvolver outros estudos evidenciando a relevância do trabalho do enfermeiro, no ato da consulta de enfermagem e seu amparo legal, avaliando a força dos músculos do assoalho pélvico, e se houver a detecção do enfraquecimento muscular iniciar a orientação sobre a importância do fortalecimento muscular na sustentação e da continência dos órgãos pélvicos, além de orientar que este fortalecimento. Orientar que deve ser uma atividade supervisionada com as devidas orientações durante as consultas e em grupos focais, de modo a melhorar a QV da população feminina de uma forma geral, com informações fáceis, que transmitem segurança às mulheres e incentivam este tratamento que permite manter a rotina e convívio social da mulher.
Partição de nicho entre espécies da família Leptodactylidae: um breve relato sobre irmãos
Authors: Brito Wenner Justino Bezerra de , Costa Rafael Dioni Leandro 
Published: February 2022

Trabalhos sobre partição de recursos entre espécies de anfíbios filogeneticamente relacionados são escassos para o domínio da Caatinga, sendo a maior parte dos estudos desenvolvidos para região de Mata Atlântica. Portanto, objetivou-se avaliar o padrão de distribuição espacial e temporal de 9 espécies da família Leptodactylidae na região de Caatinga do Estado de Pernambuco. Foram realizadas observações por via do método de Procura Visual Limitada por Tempo (PVLT) durante 18 meses nas imediações da propriedade rural Cachoeira de Maria Mendes no município de Tabira. Ocorreram 594 avistamentos de indivíduos, pertencentes a 9 espécies integrantes da família Leptodactylidae. Foram feitas análises para evidenciar a sobreposição do uso do habitat e relacionar a riqueza versus variáveis abióticas. Os resultados sugeriram máxima sobreposição do uso de habitat, entretanto, a menor sobreposição foi evidenciada para as espécies Leptodactylus troglodytes versus Leptodactylus fuscus que integram o grupo fuscus da família Leptodactylidae. Além disso, todas as espécies amostradas apresentaram comportamento generalista quanto ao uso de habitat, com uma maior ocorrência em ambientes antrópicos.