bluuebunny/crossref_metadata_2025_split huggingface dataset:
Short- and Long-Term Outcomes of Totally Versus Hybrid Minimally Invasive Ivor Lewis Oesophagectomy for Oesophageal Cancer: A Propensity Score-Matched Analysis
Authors: Gu Yi-Min , Zhang Han-Lu , Yang Yu-Shang , Yuan Yong , Hu Yang , Che Guo-Wei , Chen Long-Qi , Wang Wen-Ping 
Published: May 2022

BackgroundFew objective studies have compared totally minimally invasive Ivor Lewis oesophagectomy with hybrid procedure. Here we investigated whether the choice between totally and hybrid minimally invasive Ivor Lewis oesophagectomy influenced short-term outcomes and long-term patient survival.MethodsPatients who underwent totally or hybrid minimally invasive Ivor Lewis oesophagectomy between January 2014 and December 2017 were propensity score matched in a 1:1 ratio. The short- and long-term outcomes between the two groups were compared before and after matching.ResultsOf 138 totally and 156 hybrid minimally invasive oesophagectomy patients were eligible, 104 patients from each group were propensity score matched. Totally minimally invasive oesophagectomy was associated significantly with less blood loss (median(IQR) 100(60–150) vs 120(120–200) ml respectively; P &lt; 0.001), pneumonia (13.5 vs 25.0%; P = 0.035), pleural effusion (3.8 vs 13.5%; P = 0.014), and chest drainage (7.5(6–9) vs 8(7–9) days; P = 0.009) than hybrid procedure. There was no significant difference in 3-year overall survival rate and 3-year disease-free survival rate between the two group.ConclusionsTotally minimally invasive Ivor Lewis oesophagectomy may improve short-term outcomes and specifically reduce the incidence of pulmonary complications compared with hybrid procedure. The long-term overall survival and disease-free survival rates between the two groups were similar.
Surgical Strategies and Outcomes for Intracranial Chondromas: A Retrospective Study of 17 Cases and Systematic Review
Authors: Liu Hongyuan , Cai Qing , Li Junting , Xue Yafei , Zhang Yunze , Li Zongping , Zhao Tianzhi , Wu Yingxi 
Published: May 2022

ObjectiveTo improve the diagnosis and treatment of intracranial chondromas (ICDs) by discussing the clinical manifestations and imaging characteristics of ICDs, as well as surgical methods and treatment strategies.MethodsWe retrospectively analyzed 17 patients diagnosed with ICDs who underwent microsurgery or endoscopic transsphenoidal surgery at the Tangdu Hospital of Air Force Military Medical University and the Mianyang Central Hospital from January 2010 to November 2021. Clinical manifestations, imaging examinations, surgical treatments, and prognosis of these patients were analyzed.ResultsICDs had often been misdiagnosed as craniopharyngioma, chordoma, schwannoma, cavernous hemangioma, pituitary adenoma, and meningioma before surgery. Of the 17 cases, gross total resection (GTR) was performed in 10 cases, subtotal resection (STR) in 5, and partial resection in 2. GTR of tumor was achieved in eight cases via the endoscopic endonasal transsphenoidal approach (EETA) or the extended endoscopic endonasal transsphenoidal approach (EEETA), and the remaining patients underwent craniotomies. Clinical symptoms were assessed 1 week after surgery, 10 cases were relieved at varying degrees, and four cases had no improvement. Postoperative complications included right-limb hemiparesis, diplopia, eyelid ptosis, pulmonary infection, subcutaneous hydrops, cerebrospinal-fluid leakage (CSFL), and intracranial infection (ICI). One patient received gamma knife treatment at 3 months after surgery, two patients died due to tumor progression, and the remaining patients had no tumor recurrence.ConclusionsICDs lack typical imaging features and are often misdiagnosed. The EETA or EEETA helps improve the surgical outcomes and GTR rates of ICDs at different sites.
The Machine Learning Model for Distinguishing Pathological Subtypes of Non-Small Cell Lung Cancer
Authors: Zhao Hongyue , Su Yexin , Wang Mengjiao , Lyu Zhehao , Xu Peng , Jiao Yuying , Zhang Linhan , Han Wei , Tian Lin , Fu Peng 
Published: May 2022

PurposeMachine learning models were developed and validated to identify lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) using clinical factors, laboratory metrics, and 2-deoxy-2[18F]fluoro-D-glucose ([18F]F-FDG) positron emission tomography (PET)/computed tomography (CT) radiomic features.MethodsOne hundred and twenty non-small cell lung cancer (NSCLC) patients (62 LUAD and 58 LUSC) were analyzed retrospectively and randomized into a training group (n = 85) and validation group (n = 35). A total of 99 feature parameters—four clinical factors, four laboratory indicators, and 91 [18F]F-FDG PET/CT radiomic features—were used for data analysis and model construction. The Boruta algorithm was used to screen the features. The retained minimum optimal feature subset was input into ten machine learning to construct a classifier for distinguishing between LUAD and LUSC. Univariate and multivariate analyses were used to identify the independent risk factors of the NSCLC subtype and constructed the Clinical model. Finally, the area under the receiver operating characteristic curve (AUC) values, sensitivity, specificity, and accuracy (ACC) was used to validate the machine learning model with the best performance effect and Clinical model in the validation group, and the DeLong test was used to compare the model performance.ResultsBoruta algorithm selected the optimal subset consisting of 13 features, including two clinical features, two laboratory indicators, and nine PEF/CT radiomic features. The Random Forest (RF) model and Support Vector Machine (SVM) model in the training group showed the best performance. Gender (P=0.018) and smoking status (P=0.011) construct the Clinical model. In the validation group, the SVM model (AUC: 0.876, ACC: 0.800) and RF model (AUC: 0.863, ACC: 0.800) performed well, while Clinical model (AUC:0.712, ACC: 0.686) performed moderately. There was no significant difference between the RF and Clinical models, but the SVM model was significantly better than the Clinical model. ConclusionsThe proposed SVM and RF models successfully identified LUAD and LUSC. The results indicate that the proposed model is an accurate and noninvasive predictive tool that can assist clinical decision-making, especially for patients who cannot have biopsies or where a biopsy fails.
Disordered Gut Microbiota in Colorectal Tumor-Bearing Mice Altered Serum Metabolome Related to Fufangchangtai
Authors: Cai Mengmeng , Xiao Ya , Lin Zhibing , Lu Jinmiao , Wang Xiaoyu , Rahman Sajid Ur , Zhu Shilan , Chen Xiaoyu , Gu Jialin , Ma Yuzhu , Chen Zhaoguo , Huo Jiege 
Published: May 2022

Purpose: This study aimed to investigate the relationship between gut microbiota (GM) and serum metabolism using antineoplastic Fufangchangtai (FFCT) as the model prescription in the treatment of colorectal cancer (CRC).Methods: Tumor-bearing mice and normal mice were administered different doses of FFCT. The tumor volume of tumor-bearing mice was observed. The levels of CD4+ and CD8+ T cells in the blood, spleen, and tumor of mice were determined using a flow cytometer. The bacterial microbiota in stool samples from mice and the serum metabolomics of FFCT-treated mice and fecal microbiota transplantation mice were detected using 16s RNA sequencing and liquid chromatography–mass spectrometry (LC/MS), respectively.Results: The tumor volume of mice showed no significant decrease after FFCT intervention. The levels of CD4+ and CD8+T lymphocytes showed a significant increase under the intervention of FFCT. GM of colorectal tumor-bearing mice and healthy mice were determined, and the diversity and abundance of Firmicutes, Deferribacteres, Bacteroidetes, and Proteobacteria were significantly different between the two groups. Furthermore, we found that the levels of matrine, isogingerenone B, and armillaripin were significantly decreased in tumor-bearing mice after FFCT intervention, indicating that the tumor-induced dysbiosis of gut bacteria may affect the absorption and metabolism of FFCT. Under the intervention of FFCT, serum metabolism of mice transplanted with feces from CRC patients showed less metabolites related to FFCT than that from healthy people, indicating that GM could be a single factor affecting the metabolism of FFCT. Furthermore, we found that different doses of FFCT-treated mice had higher abundance of Roseburia, Turicibacter, and Flexispira than that in the non-intervention control group. Firmicutes and Bacteroidetes in FFCT-treated groups showed a similar trend compared to the healthy group, indicating that FFCT might correct the intestinal microenvironment by modulating gut microbiota in colorectal tumor-bearing mice.Conclusion: The dysbiosis of GM in tumor-bearing mice reduced the serum metabolites related to FFCT, and FFCT could correct the disordered GM of colorectal tumor-bearing mice to exert efficacy.
Pregnant Women’s Anxiety and Depression Symptoms and Influence Factors in the COVID-19 Pandemic in Changzhou, China
Authors: Wang Li , Yang Ni , Zhou Hua , Mao Xueqin , Zhou Ying 
Published: May 2022

BackgroundWith the coronavirus disease 2019 (COVID-19) pandemic, pregnant women’s psychological conditions have become a global challenge. The aim of the study was to identify the prevalence of anxiety and depression symptoms and analyze their influence factors among pregnant women in Changzhou, China during the COVID-19 pandemic and provide them with appropriate healthcare strategies.MethodsParticipants were 681 pregnant women who visited various obstetrics and gynecology clinics in Changzhou, China between 25 February 2020 and 7 March 2020. They were asked to complete an online survey. The Generalized Anxiety Disorder Scale-7 (GAD-7) and Patient Health Questionnaire-9 (PHQ-9) were used to detect anxious and depressive symptoms. The chi-squared test and multivariate logistic regression analysis were carried out to examine the associated factors in these groups.ResultsOverall, the prevalence rates of anxiety and depression symptoms among pregnant women were 31.72 and 36.12%, respectively, but most of them were mild. Having an irregular diet with poor subjective sleep quality, perceiving little family support, spending too much time on news related to the coronavirus, and having severe subjective life impact by the coronavirus were related to anxiety and depression symptoms. In addition, lack of physical exercise and exposure to electronic screens over 5 h per day were associated with depression symptoms.ConclusionPregnant women with an irregular diet, poor sleep quality, little family support, excessive attention to COVID-19 news, and lives impacted by the coronavirus severely are at high risk for anxiety and depression symptoms during the COVID-19 pandemic. This indicates that targeted measures to address mental health in pregnant women during the pandemic period are needed.
The Impact of COVID-19 Pandemic on Psychiatric Emergencies in Two Different Settings: Emergency Room and Community Mental Health Service
Authors: Di Lorenzo Rosaria , Pinelli Margherita , Bertani Davide , Cutino Anna , Dragone Diego , Elia Claudia , Farina Riccardo , Fiore Gianluca , Luisi Filippa , Panico Sofia , Valeo Laura , Rovesti Sergio , Ferri Paola 
Published: May 2022

BackgroundThe SARS-CoV-2 pandemic caused a public health emergency with profound consequences on physical and mental health of individuals. Emergency Rooms (ER) and Community Mental Health Services (CMHS) played a key role in the management of psychiatric emergencies during the pandemic. The purpose of the study was to evaluate urgent psychiatric consultations (UPCs) in the ERs of the General Hospitals and in the CMHS of a Northern Italian town during the pandemic period.MethodsThis monocentric observational study collected UPCs carried out in ER from 01/03/2020 to 28/02/2021 (the so called “COVID-19 period”) and the demographic and clinical characteristics of patients who required UPCs in the 12-months period, comparing these data with those collected from 01/03/2019 to 29/02/2020 (the so called “pre-COVID-19 period”). The same variables were collected for UPCs carried out in CMHS from 01/03/2020 to 31/01/2021 and compared with those collected from 01/03/2019 to 31/01/2020. The data, were statistically analyzed through STATA 12-2011.ResultsIn ER, we reported a 24% reduction in UPCs during the COVID-19 period (n = 909) in comparison with the pre-COVID-19 period (n = 1,194). Differently, we observed an increase of 4% in UPCs carried out in CMHS during the COVID-19 period (n = 1,214) in comparison with the previous period (n = 1,162). We observed an increase of UPCs in ER required by people who lived in psychiatric facilities or with disability pension whereas more UPCs in CMHS were required by older people or those living in other institutions compared to the previous period. In the COVID-19 period, the most frequent reasons for UPCs in ER were aggressiveness, socio-environmental maladjustment and psychiatric symptoms in organic disorders whereas in CMHS we reported an increase of UPCs for control of psychopharmacology therapy and mixed state/mania.ConclusionIn light of our findings, we conclude that the most vulnerable people required more frequent attention and care in both ER and CMHS during pandemic, which disrupted individuals’ ability to adapt and induced many stressful reactive symptoms. In order to reduce the impact of the COVID-19 pandemic on mental health, psychological support interventions for the general population should be implemented, having particular regard for more psychologically fragile people.
Survival Impact of Nephroureterectomy for De Novo Stage IV Nonmetastatic and Metastatic Upper Tract Urothelial Carcinoma
Authors: Lin Wei-Yu , Lin Meng-Hung , Yang Yao-Hsu , Chen Wen-Cheng , Huang Cih-En , Chen Miao-Fen , Wu Chun-Te 
Published: May 2022

BackgroundWhether nephroureterectomy (NU) provides survival benefits in patients with stage IV upper tract urothelial carcinoma (UTUC) remains unclear. We compared the effect of chemotherapy (CT) alone with that of CT combined with NU (CT + NU) on the overall survival (OS) of patients with stage IV nonmetastatic UTUC (nmUTUC) and metastatic UTUC (mUTUC).Patients and MethodsThis multicenter retrospective cohort study included the data of patients with UTUC undergoing CT alone or CT + NU from the Chang Gung Cancer Database (2002–2015) and followed them until August 2017. OS and hazard ratios (HRs) were assessed using the Kaplan–Meier method and Cox proportional hazards model, respectively.ResultsThis study included 308 patients with stage IV UTUC, comprising 139 with nmUTUC and 169 with mUTUC. Moreover, 91 (74.6%) patients with nmUTUC and 31 (25.4%) patients with mUTUC received NU. The CT + NU group had a higher 3-year OS rate (41.0.% vs 16.7%, p &lt; 0.001), longer median OS duration (20.7 vs 9.0 months, p &lt; 0.001), and lower risk of death (HR, 0.48; 95% confidence interval, 0.36–0.66; p &lt; 0.001) than did the CT-alone group. Similarly, patients with mUTUC who underwent CT + NU had a longer median OS duration (25.0 vs 7.8 months, p &lt; 0.001) and lower risk of death (HR, 0.37; 95% confidence interval, 0.23–0.59; p &lt; 0.001) than did those who received CT alone.ConclusionCompared with CT alone, NU + CT can provide survival benefits to patients with nonmetastatic and metastatic stage IV UTUC.
Probing Molecular Frame Wigner Time Delay and Electron Wavepacket Phase Structure of CO Molecule
Authors: Guo Zhenning , Ge Peipei , Fang Yiqi , Dou Yankun , Yu Xiaoyang , Wang Jiguo , Gong Qihuang , Liu Yunquan 
Published: May 2022

The time delay of photoelectron emission serves as a fundamental building block to understand the ultrafast electron emission dynamics in strong-field physics. Here, we study the photoelectron angular streaking of CO molecules by using two-color (

400
+
800

nm) corotating circularly polarized fields. By coincidently measuring photoelectrons with the dissociative ions, we present molecular frame photoelectron angular distributions with respect to the instantaneous driving electric field signatures. We develop a semiclassical nonadiabatic molecular quantum-trajectory Monte Carlo (MO-QTMC) model that fully captures the experimental observations and further ab initio simulations. We disentangle the orientation-resolved contribution of the anisotropic ionic potential and the molecular orbital structure on the measured photoelectron angular distributions. Furthermore, by analyzing the photoelectron interference patterns, we extract the sub-Coulomb-barrier phase distribution of the photoelectron wavepacket and reconstruct the orientation- and energy-resolved Wigner time delay in the molecular frame. Holographic angular streaking with bicircular fields can be used for probing polyatomic molecules in the future.
Information and Communication Technology Competence of Islamic Education Teachers
Authors: Malik Alindra Bagus , Evi Fatimatur Rusydiyah  , Nita Yalina  
Published: May 2022

Abstract : Information and Communication Technology has played its role in the educational process. It can be seen from the progress of the globalization era, teachers, especially Islamic Education teachers that must adapt and have ICT competencies that are in accordance with the needs of students in the learning process. Therefore, Islamic Education teachers must be able to develop their ICT competencies in the learning process, so that the learning process can run as expected in this era of globalization. This study used a qualitative method using a questionnaire interview instrument. The informants used were five Islamic Education teachers in the subjects of fiqh, moral aqidah, Qur'an hadith, SKI and Arabic. Then, the object used was the Islamic educational institution at MI Riyadlul Qori'in Ajung Jember. The results of this study were Islamic Education teachers at MI Riyadlul Qori'in that shown good ICT competencies from the four categories of ICT competencies.
Key words : Competency, ICT, Islamic Education teacher
Intrinsic physics in magnetic Weyl semimetal SrRuO3 films addressed by machine-learning-assisted molecular beam epitaxy
Authors: Wakabayashi Yuki K. , Krockenberger Yoshiharu , Otsuka Takuma , Sawada Hiroshi , Taniyasu Yoshitaka , Yamamoto Hideki 
Published: May 2022

Abstract
The itinerant 4d ferromagnetic perovskite SrRuO3 [bulk Curie temperature (T
C) = 165 K] has been studied extensively for many decades because of the unique nature of its ferromagnetism, metallicity, chemical stability, and compatibility with other perovskite-structured oxides. Recently, SrRuO3 has been gathering renewed interest as a magnetic Weyl semimetal and a two-dimensional ferromagnetic system. Ultra-high-quality SrRuO3 film growth techniques, combining oxide molecular beam epitaxy technology and a statistical machine learning method, have revealed new physics and physical properties of SrRuO3 as a magnetic Weyl semimetal, such as quantum transport of Weyl fermions and high-mobility two-dimensional carriers from surface Fermi arcs. This review summarizes the methods of growing ultra-high-quality SrRuO3 films and the novel physics found in them. In addition, progress in crystal structure analyses and the electrical and magnetic properties of SrRuO3 over the last decade will also be discussed.
Effects of Cl passivation on Al2O3/GaN interface properties
Authors: Nagai Taisei , Taoka Noriyuki , Ohta Akio , Makihara Katsunori , Miyazaki Seiichi 
Published: May 2022

Abstract
We investigated the effects of a HCl-based cleaning (SC2) and post-deposition annealing (PDA) on an Al2O3/GaN interface and electrical properties. X-ray photoelectron spectroscopy revealed the existence of the Cl atoms near the interface after the Al2O3 deposition and subsequent PDA, resulting in a band bending at the GaN surface. A C–V curve of a MOS capacitor with the Al2O3/GaN interface with SC2 was shifted toward the positive bias direction compared with that without SC2. It was found that PDA induced negative shifts of the C–V curves, and that the SC2 treatment increases interface trap density at the Al2O3/GaN interface. These results indicate that the Cl termination of the GaN surface has clear impacts on the interface and electrical properties.
الذكاء اللغوي لدى تلاميذ الصف الأول الابتدائي من الملتحقين وغير الملتحقين برياض الأطفال
Authors: Mr. Dr. Iman Abbas Ali Khafaf  
Published: May 2022

لقد أحدثت نظرية الذكاءات المتعددة ثورة في المجالين التربوي والتعليمي، فلقد وجه جاردنر النظر إلى الطاقات لدى كل فرد والتي إذا ما تم تدريبها جيداً سيولد جيل من الموهوبين والمتميزين لديهم أساليب متعددة ومتنوعة لحل المشكلات ولديهم القدرة على التكيف مع مختلف الأحوال ولديهم طرق متعددة للتعامل مع معطيات العصر وما فيه من متغيرات (الأنصاري والفيل،2009: 175).
ومع ميلاد نظرية الذكاء المتعددة Multiple Intelligences ازداد فهمنا عمقاً بطبيعة الذكاء الإنساني فيمتلك الإنسان مجموعة من الذكاءات وليس ذكاءً واحداً. فلا يستطيع احد منا أن ينكر أهمية الذكاء المتعدد في مجالات الحياة المختلفة سواء في مجال التعليم أم في مجال التدريب أم في المواقف الاجتماعية أم الحياتية على اختلافها كما إن قضية وضع الرجل المناسب في المكان المناسب تتطلب معرفة إمكانات الفرد العقلية كما تتطلب معرفة متطلبات العمل بما يضمن نجاح الفرد في عمله، وفي ضوء ما تقدم يمكن تلخيص مشكلة البحث بالتساؤل الآتي:
والذكاء اللغوي هو احد أنواع الذكاء المتعدد التي لاقت اهتماما كبيرا من علماء النفس والتربية وكان لهذا الاهتمام دور كبير في الاعتماد على استخدام استراتيجيات الذكاء اللغوي وأنشطته في عملية التعلم. وأشار جاردنر (1983) إلى الذكاء اللغوي مستخدما الشعر والكتابة الإبداعية كأمثلة لهذا النمط من الذكاء أو الموهبة وعلى الرغم من تركيزه على هذه المجالات من الخبرة، والتي تمثل فيها العنصر الأساسي، إلا أن جاردنر أشار إلى أنه في معظم المجتمعات تعد اللغة " أداة "يستخدمها العلميون والتاريخيون والنقاد والروائيون وكل الباحثين، إلا أن بعضهم يستخدم اللغة بطريقة أفضل من بعضهم الأخر، وهذا ما يؤكد أن هؤلاء الأشخاص جميعهم يتمتعون بدرجة من الموهبة.
وحصل الذكاء اللغوي على النصيب الأكبر من بين اهتمامات الباحثين في الذكاءات المتعددة، فقد صنف جاردنر الذكاء اللغوي في المرتبة الأولى، وعده من أهم الذكاءات التي تساعد المتعلم على تنمية الذكاءات الأخرى، ومنها يأتي تساؤل الباحثة، الآتي:
هل للالتحاق برياض الأطفال دور في تنمية الذكاء اللغوي لدى تلاميذ الصف الاول الابتدائي ؟
Sistem Operasi Menggunakan Metode Konversi di Perusahaan Rokok Manufacturing
Authors: Arum Lutfia Puspa Indah 
Published: May 2022

Rokok merupakan salah satu sumber pengeluaran masyarakat Indonesia, produk yang dibenci tapi dirindukan ini menghasilkan bisnis besar dan kebutuhan besar bagi perekonomian Republik Indonesia. Hampir 54% total penduduk Indonesia adalah perokok aktif, dari peluang bisnis dan keuntungan dalam memproduksi rokok di Indonesia maka dilakukan penelitian diperusahaan rokok berkembang yang baru merintis. Permintaan peminat rokok dari data perusahaan cukup banyak yaitu rata-rata setiap bulan permintaan agen rokok sekitar 65.264.000 (enam puluh lima juta dua ratus enam puluh empat ribu) per batang. Dengan memenuhi permintaan konsumen agar pengiriman dapat tepat waktu dan cepat maka dilakukan sistem operasi menggunakan metode konversi secara tersistem. Dari konversi satuan box yang akan dikonversi ke satuan kg, trey, batangan, pak, press dan akan di konversi kembali dalam satuan box. Sistem operasi (WIP) pada mesin maker dan mesin HLP 20.