bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mechanical or biologic prostheses for mitral valve replacement: A systematic review and meta‐analysis
Authors: Yu Jun , Qiao En , Wang Wei 
Published: June 2022

AbstractEither a mechanical or bioprosthetic valve is used in patients undergoing mitral valve replacement (MVR). However, the optimal mitral prosthesis remains controversial. The aim of this meta‐analysis was thus to compare outcomes between mechanical mitral valve replacement (MVRm) and bioprosthetic mitral valve replacement (MVRb) for MVR patients. We searched Embase, PubMed, Web of Science, and Cochrane Library databases from January 1, 2000 to October 31, 2021 for studies that directly compared surgical outcomes of MVRm and MVRb. A total of 22 studies with 35 903 patients were included in the meta‐analysis (n = 23 868 MVRm and n = 12 035 MVRb). The MVRm group displayed lower long‐term all causes mortality (HR, 0.84; 95% confidence interval [CI]: 0.77−0.91; p < .0001; I² = 51%), and fewer mitral reoperation (hazard ratio [HR]: 0.34; 95% CI: 0.23−0.50; p < .00001; I² = 74%) than MVRb group. However, the MVRm group was associated with a greater risk of major bleeding events (HR: 1.21; 95% CI: 1.14−1.29; p < .00001; I² = 0%), stroke and systemic embolism (HR: 1.20; 95% CI: 1.10−1.32; p < .0001; I² = 0%) in matched or adjusted data. No significant difference was observed between MVRm and MVRb on operative mortality in matched/adjusted group (risk ratios: 0.83; 95% CI: 0.66−1.05; p = .12; I² = 0%). The results were consistent with patients aged under 70 years old. Patients who received a MVRm is associated with 16% lower risk of long‐term mortality and 66% lower risk of mitral reoperation, but 20% greater risk of stroke or systemic embolism, 21% greater risk of major bleeding compared with MVRb in matched/adjusted studies group, which were consistent to patients younger than the age of 70 years who underwent MVR.
Application and usefulness of a new eight‐wire basket catheter for endoscopic extraction of small common bile duct stones: A retrospective multicenter study
Authors: Inatomi Osamu , Katayama Masanobu , Soga Koichi , Yamamoto Takashi , Mikami Takao , Morita Yukihiro , Nakajima Jun , Shintani Shuhei , Yagi Yuki , Kishi Yuki , Matsumura Kazuyoshi 
Published: June 2022

AbstractObjectivesDistally located small common bile duct stones are often difficult to treat or grasp endoscopically. Therefore, multiple devices, such as baskets or balloon catheters, are frequently used in such cases. However, it is desirable to use a single device for stone extraction from the perspective of cost‐effectiveness. In this multicenter study, we evaluated the efficacy of a new eight‐wire basket catheter for extracting small (≤10 mm) common bile duct stones.MethodsWe retrospectively analyzed the records of 144 patients who underwent stone extraction using the eight‐wire basket catheter for common bile duct stones ≤10 mm. The success rate of complete stone extraction and the risk factors for the difficulty in stone extraction with the eight‐wire catheter alone were mainly evaluated.ResultsThe success rate of stone extraction with the eight‐wire catheter alone was 86.1%. The final rate of complete stone extraction was 98.0%. The mean of the maximum diameter of the common bile duct and the largest stone dimension were 10.5 ± 3.5, and 5.1 ± 2.1 mm, respectively. Common bile duct diameter ≥12 mm and stone diameter ≥6 mm were identified as independent risk factors for the difficulty in stone extraction with the eight‐wire catheter alone.ConclusionsThe success rate of the new eight‐wire basket for small common bile duct stone extraction was acceptable. The device is beneficial and could be used from the start for the extraction of small stones < 6 mm.
Dialectical behavior therapy compared to cognitive behavior therapy in binge‐eating disorder: An effectiveness study with 6‐month follow‐up
Authors: Lammers Mirjam W. , Vroling Maartje S. , Crosby Ross D. , van Strien Tatjana 
Published: June 2022

AbstractObjectiveTo evaluate whether the results of a quasi‐randomized study, comparing dialectical behavior therapy for binge‐eating disorder (DBT‐BED) and an intensive, outpatient cognitive behavior therapy (CBT+) in individuals with BED, would be replicated in a nonrandomized study with patients who more closely resemble everyday clinical practice.MethodPatients with (subthreshold) BED (N = 175) started one of two group treatments: DBT‐BED (n = 42) or CBT+ (n = 133), at a community eating disorder service. Measures of eating disorder pathology, emotion regulation, and general psychopathology were examined at end of treatment (EOT) and at 6‐month follow‐up using generalized linear models with multiple imputation.ResultsBoth treatments lead to substantial decreases on primary and secondary measures. Statistically significant, medium‐size differences between groups were limited to global eating disorder psychopathology (d = −.62; 95% CI = .231, .949) at EOT and depressive symptoms at follow‐up (d = −.45; 95% CI = .149, 6.965), favoring CBT+. Dropout of treatment included 15.0% from CBT+ and 19.0% from DBT‐BED (difference nonsignificant).DiscussionDecreases in global eating disorder psychopathology were achieved faster with CBT+. Overall, improvements in DBT‐BED were comparable to those observed in CBT+. Findings of the original trial, favoring CBT+ on the number of OBE episodes, emotional dysregulation and self‐esteem at EOT, and on eating disorder psychopathology and self‐esteem at follow‐up, were not replicated. With similar rates of treatment dropout and about half of the therapy time used in CBT+, DBT‐BED can be considered a relevant treatment for BED in everyday clinical practice.Public SignificanceIn this effectiveness study, dialectical behavior therapy (DBT) resulted in clinically relevant improvements in individuals with binge eating disorder. Changes were broadly comparable to those of cognitive behavior therapy (CBT), the current treatment of choice. Although CBT resulted in decreases in eating disorder psychopathology faster, there was a trend toward relapse in CBT at 6‐month follow‐up. Therefore, the less costly DBT‐program can be considered a relevant treatment in clinical practice.
The relationship between the Mediterranean diet and Axis I disorders: A systematic review of observational studies
Authors: Madani Samaneh , Ahmadi Afsane , Shoaei‐Jouneghani Firoozeh , Moazen Mahsa , Sasani Najmeh 
Published: June 2022

AbstractAxis I disorders are one of the major health burdens worldwide. Evidence suggests that Mediterranean diet has key biological factors associated with reducing the progression of these disorders. This systematic review aimed to clarify the relationship between Mediterranean diet and Axis I disorders. PubMed and Scopus databases were searched from January 2016 up to June 2021. Those observational studies in English language that assessed the relationship between Mediterranean diet and Axis I disorders (such as depression, anxiety, eating disorders, schizophrenia, etc.) were included in this review. The Newcastle–Ottawa Scale was used to evaluate the quality of studies. Thirty‐six studies (15 cohorts, 19 cross‐sectional, and 2 case–control) met the inclusion criteria. The results revealed that more than two‐thirds of the studies (25 studies, 69.44%) had significant protective relationship between receiving Mediterranean diet and reducing the symptoms or incidence of Axis I disorders. Most studies were performed on depression (29 studies measured depression at least as one of the Axis I disorders), of which 72.41% reported an inverse relationship. There were also 9 studies on anxiety (studies that measured anxiety at least as one of the Axis I disorders), that 77.77% of them observed protective association. Moreover, majority of the studies (25 studies, 69.44%) had high quality, of which 76% found an inverse relationship. In conclusion, it seems that the Mediterranean diet can reduce the symptoms or the occurrence of Axis I disorders (especially depression and anxiety). However, more extensive review studies, particularly with interventional designs, are necessary to prove the result.
Flow cytometric evaluation of measurable residual disease in chronic lymphocytic leukemia: Where do we stand?
Authors: D’Arena Giovanni , Sgambato Alessandro , Volpe Silvestro , Coppola Giuseppe , Amodeo Rachele , Tirino Virginia , D’Auria Fiorella , Statuto Teodora , Valvano Luciana , Pietrantuono Giuseppe , Deaglio Silvia , Efremov Dimitar , Laurenti Luca , Aiello Antonella 
Published: June 2022

AbstractMeasurable residual disease (MRD) has emerged as a relevant parameter of response to therapy in chronic lymphocytic leukemia (CLL). Although several methods have been developed, flow cytometry has emerged as the most useful and standardized approach to measure and quantify MRD. The improved sensitivity of MRD measurements has been paralleled by the development of more effective therapeutic strategies for CLL, increasing the applicability of MRD detection in this setting. Chemotherapy and chemoimmunotherapy have firstly demonstrated their ability to obtain a deep MRD. Combined targeted therapies are also demonstrating a high molecular response rate and prospective trials are exploring the role of MRD to guide the duration of treatment in this setting. In this review we briefly summarize what we have learned about MRD with emphasis on its flow cytometric detection.
Estimating evapotranspiration within a dryland watershed: Comparison of eddy‐covariance observations, water budget estimates, and satellite‐based products
Authors: Liu Yi , Zheng Yuejun , Li Wenpeng , Zhou Tiantian 
Published: June 2022

AbstractAccurate and continuous estimates of evapotranspiration (ET) are crucial for comprehending associated hydrological processes, especially in dryland watersheds. However, there remains a scarcity of comprehensive evaluations of multi‐source ET estimates' performance and uncertainties. To further assist ET estimation improvement and water resources management, we incorporated diffuse radiation partitioning and water‐carbon coupling processes into the satellite‐driven Vegetation Interface Processes (VIP) model for estimating ET in the Heihe River Basin, Northwest China, and compared it with eddy covariance (EC) observations, water budget estimates, and five global satellite‐based products from Breathing Earth System Simulator (BESS), MODerate‐resolution Imaging Spectroradiometer (MODIS), Penman‐Monteith‐Leuning (PML), Operational Simplified Surface Energy Balance (SSEBop), and Global LAnd Surface Satellite (GLASS). Sobol' sensitivity analysis was applied to the VIP model. Uncertainties in ET estimates were identified by the three‐cornered hat method. Results indicate that stomatal conductance coefficient, quantum efficiency, and clear sky index were dominant influencing parameters for VIP ET. Moreover, VIP and GLASS ET were in strong agreement with the EC‐based ET, although SSEBop ET was not, and MODIS ET could not capture seasonal variations. VIP could best represent ET dynamics from water budgets on the basin scale, followed by PML. During the period 2003–2015, GLASS, PML, and VIP provided reasonable ET estimates in this region, with an annual ET of 159.3, 153.2, and 173.5 mm, respectively, across the basin. Furthermore, ET algorithm benefits were presented: BESS and VIP, including diffuse radiation partitioning, performed better in cropland; PML and VIP that address water‐carbon coupling were stable and independent of the aridity index, and GLASS could considerably reduce uncertainty. The findings contribute to the collective knowledge of ET estimates in similar dryland areas and are relevant worldwide.
ARDL bounds test for cointegration: Replicating the Pesaran et al. (2001) results for the UK earnings equation using R
Authors: Natsiopoulos Kleanthis , Tzeremes Nickolaos G. 
Published: June 2022

SummaryThis paper replicates the UK earnings equation using the autoregressive distributed lag (ARDL) modeling approach and the bounds test for cointegration by Pesaran et al. (Journal of Applied Econometrics, 2001, 16(3), 289–326). The findings from the narrow sense fully replicate the original results using the open‐source language R and the ARDL package. In the wide sense replication, augmented data are employed, thus extending the end period from 1997:Q4 to 2019:Q4, using an alternative measure for union power. Adopting the new dataset, this study reinvestigates the UK earnings equation, thereby providing supporting evidence of a long‐run relationship and reveals empirical findings about the long‐run effects of productivity, unemployment, tax wedge, and union power on wages.
Dipolar 1,3‐cycloaddition of thioformaldehydeS‐methylide (CH2SCH2) to ethylene and acetylene. A comparison with (valence) isoelectronicO3,SO2,CH2OOandCH2SO
Authors: Salta Zoi , Vega‐Teijido Mauricio , Katz Aline , Tasinato Nicola , Barone Vincenzo , Ventura Oscar N. 
Published: June 2022

AbstractMethods rooted in the density functional theory and in the coupled cluster ansatz were employed to investigate the cycloaddition reactions to ethylene and acetylene of 1,3‐dipolar species including ozone and the derivatives issued from replacement of the central oxygen atom by the valence‐isoelectronic sulfur atom, and/or of one or both terminal oxygen atoms by the isoelectronic CH2group. This gives rise to five different 1,3‐dipolar compounds, namely ozone itself (O3), sulfur dioxide (SO2), the simplest Criegee intermediate (CH2OO), sulfine (CH2SO), and thioformaldehydeS‐methylide (CH2SCH2, TSM). The experimental and accurate theoretical data available for some of those molecules were employed to assess the accuracy of two last‐generation composite methods employing conventional or explicitly correlated post‐Hartree‐Fock contributions (jun‐Cheap and SVECV‐f12, respectively), which were then applied to investigate the reactivity of TSM. The energy barriers provided by both composite methods are very close (the average values for the two composite methods are 7.1 and 8.3 kcal mol−1for the addition to ethylene and acetylene, respectively) and comparable to those ruling the corresponding additions of ozone (4.0 and 7.7 kcal mol−1, respectively). These and other evidences strongly suggest that, at least in the case of cycloadditions, the reactivity of TSM is similar to that of O3and very different from that of SO2.
Combined prognostic value of preoperative serum thyrotrophin and thyroid hormone concentration in papillary thyroid cancer
Authors: Liu Yushu , Huang Yanyi , Mo Guoheng , Zhou Tao , Hou Qian , Shi Chaoqun , Yu Jichun , Lv Yunxia 
Published: June 2022

AbstractBackgroundA growing number of studies have found a close association between thyroid hormones and thyrotrophin (TSH), and they also have prognostic significance in some cancer types; this study aimed to investigate the prognostic value of free triiodothyronine (fT3), free thyroxine (fT4), fT3/fT4, TSH, and their combination in patients with papillary thyroid carcinoma (PTC).MethodsThis study retrospectively analyzed the relevant data of 726 newly diagnosed PTC patients. Both univariate and multivariate analyses were used to predict the recurrence rate, and a risk score was established. In addition, with the use of a random survival forest, a random forest (RF) score was constructed. After calculating the area under the curve (AUC), the diagnostic efficacy of risk score, RF score, and four indicators was compared.ResultsfT3, fT4, fT3/fT4, and TSH were strongly associated with some invasive clinicopathological features and postoperative recurrence. Patients with high expression of fT4 and TSH have a high risk of recurrence. By contrast, patients with high expression of fT3 and fT3/fT4 have a low risk of recurrence. At the same time, the combined use of various indicators is more helpful for establishing an accurate diagnosis. By comparison, we found that the RF score was better than the risk score in terms of predicting the recurrence of PTC.ConclusionThe diagnostic accuracy of a combination of fT3, fT4, fT3/fT4, and TSH can help improve our clinical estimate of the risk of recurrent PTC, thus allowing the development of a more effective treatment plan for patients.
Unusual lophophore innervation in ctenostome Flustrellidra hispida (Bryozoa)
Authors: Temereva Elena N. , Isaeva Maria A. , Kosevich Igor A. 
Published: June 2022

AbstractSince ctenostomes are traditionally regarded as an ancestral clade to some other bryozoan groups, the study of additional species may help to clarify questions on bryozoan evolution and phylogeny. One of these questions is the bryozoan lophophore evolution: whether it occurred through simplification or complication. The morphology and innervation of the ctenostome Flustrellidra hispida (Fabricius, 1780) lophophore have been studied with electron microscopy and immunocytochemistry with confocal laser scanning microscopy. Lophophore nervous system of F. hispida consists of several main nerve elements: cerebral ganglion, circumoral nerve ring, and the outer nerve ring. Serotonin‐like immunoreactive perikarya, which connect with the circumoral nerve ring, bear the cilium that directs to the abfrontal side of the lophophore and extends between tentacle bases. The circumoral nerve ring gives rise to the intertentacular and frontal tentacle nerves. The outer nerve ring gives rise to the abfrontal neurites, which connect to the outer groups of perikarya and contribute to the formation of the abfrontal tentacle nerve. The outer nerve ring has been described before in other bryozoans, but it never contributes to the innervation of tentacles. The presence of the outer nerve ring participating in the innervation of tentacles makes the F. hispida lophophore nervous system particularly similar to the lophophore nervous system of phoronids. This similarity allows to suggest that organization of the F. hispida lophophore nervous system may reflect the ancestral state for all bryozoans. The possible scenario of evolutionary transformation of the lophophore nervous system within bryozoans is suggested.
A proposal of drain removal criteria in hepatobiliary resection
Authors: Watanabe Nobuyuki , Mizuno Takashi , Yamaguchi Junpei , Yokoyama Yukihiro , Igami Tsuyoshi , Onoe Shunsuke , Uehara Kay , Sunagawa Masaki , Ebata Tomoki 
Published: June 2022

AbstractBackgroundStandardized criteria for drain removal in hepatobiliary resection are lacking. Here, we evaluated the outcomes of delayed removal policy in this extended surgery.MethodsPatients undergoing hepatectomy with biliary reconstruction between 2012 and 2018 were retrospectively reviewed. The drains were removed on postoperative day (POD) 7 when the drainage fluid was grossly serous, biochemically normal, and negative for bacterial contamination as assessed by Gram staining; additionally, no abnormal fluid collection was confirmed by computed tomography. Clinically relevant abdominal complications (CRACs), including biliary leakage, pancreatic fistula or intra‐abdominal abscess, served as the primary outcome measure.ResultsAmong 374 study patients, surgical drains were removed in 166 (44.3%) patients who met the criteria. Of these patients, 16 (9.6%) patients subsequently required additional drainage due to CRAC. Drains were retained and exchanged in 208 (55.6%) patients who did not meet the criteria. Of these, exchanged drains were soon removed in 34 patients due to no signs of CRAC. The diagnostic ability of the criteria revealed 0.916 sensitivity, 0.815 specificity, and 0.866 accuracy.ConclusionThe four findings on POD 7 worked well as criteria for drain removal, and these criteria may be helpful in drain management after hepatobiliary resection.
Clinical and virologic factors associated with outcomes of COVID‐19 before and after vaccination among Veterans: Retrospective analysis from six New England states
Authors: Lee Megan , Cosentino Danielle , Kyriakides Tassos C. , Cavallaro Tricia , Stack Gary , Gupta Shaili 
Published: June 2022

AbstractWe aimed to characterize clinical and demographic factors affecting clinical outcomes of COVID‐19 and describe viral epidemiology among unvaccinated Veterans in New England. Veterans infected with COVID‐19 in Veterans Administration healthcare systems in six New England states from April 8, 2020, to September 2, 2021, were correlated with outcomes of 30‐day mortality, nonpsychiatric hospitalization, and intensive care unit admission (ICU‐care). We sequenced 827 viral genomes. Of 3950 Veterans with COVID‐19 before full vaccination, 81% were White, 8% were women, and the mean age was 60 years. Overall, 19% of Veterans required hospitalization, 2.8% required ICU care, and 4.9% died. In this largely male and older cohort, poor outcomes correlated with increasing age. Most New England Veterans (>97%) were infected with B.1 sublineages with the D614G mutation in 2020 and early 2021. B.1.617.2 lineage (68%) predominated after July 2021.
Towards an alcohol‐free process for the production of palm phytonutrients via enzymatic hydrolysis of crude palm oil using liquid lipases
Authors: Adiiba Siti Hanifah , Chan Eng‐Seng , Lee Yee Ying , Amelia  , Chang Mun Yuen , Song Cher Pin 
Published: June 2022

AbstractBACKGROUNDCrude palm oil (CPO) is rich with phytonutrients such as carotenoids and tocols which possesses many health benefits. The aim of this research was to develop a methanol‐free process to produce palm phytonutrients via enzymatic hydrolysis. In this work, triacylglycerol was hydrolyzed into free fatty acids (FFAs) using three different types of liquid lipases derived from Aspergillus oryzae (ET 2.0), Aspergillus niger (Habio) and Candida antartica (CALB).RESULTSET 2.0 was found to be the best enzyme for hydrolysis. Under the optimum condition, the FFA content achievable was 790 g kg−1 after 24 h of reaction with 1:1 water‐to‐oil mass ratio at 50 °C and stirring speed of 9 × g. Furthermore, with the addition of 2 g kg−1 ascorbic acid, it was found that 98% of carotenoids and 96% of tocols could be retained after hydrolysis.CONCLUSIONThis work shows that enzymatic hydrolysis, which is inherently safer, cleaner and sustainable is feasible to replace the conventional methanolysis for the production of palm phytonutrients. © 2022 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Shape‐Dependent Complementary Ditopic Terpyridine Pair with Two Levels of Self‐Recognition for Coordination‐Driven Self‐Assembly
Authors: Li Kehuan , Zhang Shunran , Hu Yaqi , Kang Shimin , Yu Xiujun , Wang Heng , Wang Ming , Li Xiaopeng 
Published: June 2022

AbstractMolecular recognition in biological systems plays a vital role in the precise construction of biomacromolecules and the corresponding biological activities. Such recognition mainly relies on the highly specific binding of complementary molecular pairs with complementary sizes, shapes, and intermolecular forces. It still remains challenging to develop artificial complementary motif pairs for coordination‐driven self‐assembly. Herein, a series of shape‐dependent complementary motif pairs, based on ditopic 2,2′:6′,2″‐terpyridine (TPY) backbone, are designed and synthesized. The fidelity degrees of self‐assemblies from these motifs are carefully evaluated by multi‐dimensional mass spectrometry, nuclear magnetic resonance spectroscopy, and molecular modeling. In addition, two levels of self‐recognition in both homoleptic and heteroleptic assembly are discovered in the assembled system. Through finely tuning the shape and size of the ligands, a complementary pair is developed with error‐free narcissistically self‐sorting at two levels of self‐recognition, and the intrinsic principle is carefully investigated.