bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengembangan Modul Pembelajaran PAI Dan Budi Pekerti Dalam Menunjang Pembelajaran Daring Di SD Negeri 59 Payakumbuh
Authors: Novira Riza , Supriadi  
Published: October 2022

Penelitian ini dilatarbelakangi oleh kurangnya ketersediaan buku paket Pendidikan Agama Islam dan Budi Pekerti di sekolah. Dan selama ini sekolah masih belum memiliki persediaan sumber belajar berupa modul. Beberapa sumber belajar masih terbatas dengan bahan ajar yang sederhana. Terutama dalam masa pandemi Covid 19 ini pembelajaran yang dilakukan dengan jarak jauh selama ini terdapat beberapa permasalahan. Guru sebagai seorang pendidik di haruskan mampu menciptakan bahan ajar sesuai dengan kondisi siswa pada saat ini. Penelitian ini bertujuan untuk mengembagkan bahan ajar berupa modul pada mata pelajaran PAI dan Budi Pekerti di kelas IV SD. Serta untuk mengetahui dampak penggunaannya terhadap peningkatan hasil belajar siswa kelas IV SD Negeri 59 Payakumbuh. Jenis penelitian yang digunakan adalah penelitian pengembangan atau Reseach and Development (R & D) dengan menggunakan model ADDIE. Adapun tahap-tahap pengembangannya adalah sebagai berikut: 1) Tahap Analisis (Analyze), 2) Tahap Desain (Design), 3) Tahap Pengembangan (Development), 4) Tahap Implementasi (Implementation), 5) Tahap Evaluasi (Evaluation). Hasil penelitian menunjukkan bahwa (1) Penelitian pengembangan ini menghasilkan produk berupa modul pembelajaran PAI dan Budi Pekerti yang bertujuan untuk meningkatkan motivasi belajar siswa kelas IV SD Negeri 59 Payakumbuh (2) Hasil penelitian dan pengembangan modul pembelajaran PAI dan Budi Pekerti ini memenuhi kriteria valid dengan presentase hasil uji coba oleh ahli materi, desain dan bahasa diperoleh nilai sedang 1 atau 7,31 %, nilai tinggi 12 atau 58,53 %, dan nilai sangat tinggi 16 atau 39,02 % dengan interpretasi valid, dan guru mata pelajaran nilai tinggi 15 atau 28,84 %, dan nilai sangat tinggi 37 atau 71,15 % dengan interpretasi sangat praktis. (3) Terdapat peningkatan yang signifikan terhadap hasil belajar siswa. Nilai rata-rata pre-test kelas eksperimen sebesar 70,15 dan rata-rata pre-test kelas kontrol adalah 67,69. Sedangkan nilai post-tes kelas eksperimen adalah 88,92 dan nilai pos-test kelas kontrol adalah 83,38. Hasil uji validitas menggunakan SPSS memperlihatkan nilai dari Cronbach's Alpha yang dihasilkan adalah 0.835 lebih besar dari nilai alpha 0.05. Hasil uji praktikalitas memperlihatkan nilai Cronbach's Alpha yang dihasilkan adalah 0.852 lebih besar dari nilai alpha 0.05. Sehingga dapat diartikan bahwa praktikalitas Modul (produk) ini dalam pandangan guru PAI memiliki tingkat reliabilitas yang sangat tinggi. Hasil nilai yang diperoleh siswa setelah menggunkan bahan ajar hasil pengembangan mengalami peningkatan, nilai rata-rata yang diperoleh sebelum menggunakan produk pengembangan adalah : kelas eksperimen 70,15 dan kelas konrol 67,69. Setelah menggunakan produk hasil pengembangan nilai yang diperoleh siswa meningkat menjadi: kelas eksperimen 88,92 dan kelas kontrol 83,38.
impact of COVID-19 pandemic on career choice in a secondary school wide survey
Authors: Baskar Aditi , Quigley Laura , Sangha Kam 
Published: October 2022

Abstract
Introduction: This survey aims to investigate the impact of the Covid-19 pandemic on career choices amongst high school students.
Methods: This is a school authorized electronic survey of students in years 10 - 13 in our boys and girls campuses of the independent schools of the King Edward VI Foundation, Birmingham. Comparison of proportion was statistically assessed using online Chi-square test with a significance level of p<0.05.
Results: 225 of 859 students (26%) responded. A healthcare career is definitely considered by 21% and possibly by 22%. Over the course of the pandemic, 30% of responders changed their career aspirations: 38% of those that are currently certain or considering a healthcare career compared to 24% of those considering a non-healthcare career.
Conclusions: Our survey highlights that the COVID-19 pandemic has influenced career choices amongst secondary school students and is most pronounced amongst those considering healthcare.
Development of a welfare assessment protocol and assessment of dairy cattle welfare in Haryana and Punjab states of Northern India
Authors: Kamboj ML , Kumar C , Mahla V 
Published: October 2022

AbstractThe aim of this study was to develop an on-farm dairy cattle welfare assessment protocol at different-sized farms in two major commercial dairy farming states in India. For developing the protocol, the basic ‘Integrative Diagnostic System Welfare’ (IDSW) framework was modified to include three welfare components (animal housing and other facilities; feeds and feeding practices; and animal health, performance and behaviour) and 20 welfare indicators (ten resource- and ten animal-based). Each indicator was weighed on a value scale with an aggregate welfare score of 100. The protocol was tested for feasibility, validity and reliability using Cronbach's alpha and Guttman split-half coefficient. Using this protocol, welfare was assessed on 60 commercial farms in Punjab and 50 in Haryana, divided into three adult herd sizes: small (S < 20), medium (M = 21–50) and large (L > 50). Welfare scores in L (76.60 [± 1.70]) and M (68.40 [± 2.27]) sized herds in Punjab were higher than in S herds (60.80 [± 2.77]). In Haryana these were higher in L (68.1 [± 1.18]) than in S (60.50 [± 2.74]) and M (59.35 [± 2.17]) sized herds. The aggregate average welfare score was higher in Punjab (68.60 [± 1.49]) than in Haryana (62.65 [± 2.02]). Welfare at more than 75% of the farms in Punjab and more than 50% of those in Haryana was judged as ‘acceptable.’ Six welfare indicators in Punjab and eight in Haryana were most compromised. Four indicators (microclimate protection measures, availability of milking parlour, cow cleanliness and reproductive efficiency) were the most compromised indicators in both states. To improve dairy cattle welfare in these states we recommend an emphasis on improving housing and feeding conditions, especially at small and medium farms, along with heat stress amelioration measures and improving hygiene and reproductive efficiency at all farms.
A preliminary survey on the occurrence of barbering in laboratory mice in Germany
Authors: Kahnau P , Jaap A , Hobbiesiefken U , Mieske P , Diederich K , Thöne-Reineke C , Lewejohann L , Hohlbaum K 
Published: October 2022

AbstractAlthough barbering is common in laboratory mice (Mus musculus), little is known about its effects, both on animal welfare and the research data collected from barbered mice. To gain information on the occurrence of barbering and related risk factors in animal facilities in Germany, we performed an online survey. All the respondents (n = 32 animal facilities) had experienced barbering in their facility. In most cases, less than 10% of the mice were affected, and the age of onset was mostly observed to be 2 to < 6 months. A greater susceptibility was reported in females and in C57BL/6 mice, but this could not be verified as the prevalence of females and the C57BL/6 strain was unknown. One facility reported differences in barbering between commercial animal suppliers. Barbering was also recorded in mice provided with enrichments, such as houses, wood-gnawing blocks, tunnels, running wheels/discs or cage dividers. None of the responding facilities provided swings, structural elements such as an elevated platform or foraging and cognitive enrichment. The questions of whether barbering may have an impact on study results and whether victims of barbering can be used for experiments revealed mixed opinions, most likely due to a lack of data on potential effects. This survey clearly demonstrated barbering to be a widely underestimated problem that is not given enough attention. We suggest that the occurrence of barbering should be systematically documented in every animal facility and reported in research articles, to provide a greater understanding of barbering and its potential effects.
Using sensors to detect individual responses of lambs during transport and pre-slaughter handling and their relationship with meat quality
Authors: Ogun S , Viola I , Obertino M , Manenti I , Ala U , Brugiapaglia A , Battaglini L , Perona G , Baratta M 
Published: October 2022

AbstractRapid analysis of animal welfare is a crucial component of the assessment of the meat quality supply chain, ensuring management procedures confer optimum standards of welfare. Further, there is increasing interest in monitoring the welfare state of each individual animal. This study looked at transport and pre-slaughter management in terms of meat quality evaluated in two breeds (Biellese and Sambucana) across two different farming systems. Precision Livestock Farming (PLF) technologies were implemented, including accelerometer and rumination activity ear-tag sensors, as potential welfare indicators during transportation and pre-slaughter. Significant correlations were found between sensors’ parameters, such as total activity and rumination and physical and chemical meat quality characteristics such as drip loss. Lambs with lower rumination and/or lower total activity were found to have lower drip loss indicating reduced meat quality. Sensors have the potential to help detect those animals particularly sensitive to stressors during transport and pre-slaughter handling and may allow real-time measurement of the impact of transport and handling in abattoirs, enabling better animal management via specific customised strategies.
Enzymatic Activities of Halotolerant and Halophilic Fungi Isolated from Iko River Estuary, South-South Nigeria
Authors: Ufot Ekemini A. , Antia Ukponobong E. , Umoh Veronica J. , Udomessien Cheryl K. 
Published: October 2022

Aim: Fungi that can tolerate unfavorable conditions are a potential source of stable bioactive metabolites that can be used for various industrial processes. Therefore this study aimed to isolate halotolerant and halophilic fungi from the Iko river estuary and screen them for three industrially important enzymes: amylase, cellulase, and mannanase.
Place and Duration of Study: Department of Microbiology, Akwa Ibom State University, Nigeria, between September 2021 and August 2022.
Methodology: Five sediment-dwelling fungi isolated from three locations along the Iko river estuary were assayed for their halotolerance on PDA containing different NaCl concentrations while their amylolytic, cellulolytic, and mannolytic activities were evaluated on agar plates containing 10% NaCl. The highest producer of the screened enzymes was identified using molecular techniques and further subjected to various submerged fermentation conditions to optimize the production of salt tolerant amylase, cellulase, and mannanase.
Results: All isolates were halotolerant, best adapted to a salinity of 5% NaCl (w/v), and capable of secreting at least one of the three tested enzymes in 10% NaCl (w/v). Aspergillus niger isolate L2S1 had the highest enzymatic index among other isolates thus requiring optimization. The optimum production of amylase, cellulase, and mannanase was obtained at an incubation temperature of 30oC, initial pH of 6.0, and NaCl concentration of 5% (w/v). Out of the tested agro-wastes, wheat bran was most suited for the production of amylase, corncob was optimum for cellulase production, and maximum mannanase yield was obtained using copra meal. Amylase and cellulase production was optimal at 96 hours of incubation, whereas mannanase required 144 hours of fermentation to reach its maximum activity.
Conclusion: Aspergillus niger isolate L2S1 was capable of utilizing different carbon sources including cheap agro-residues as substrates for the production of halostable amylase, cellulase, and mannanase.
Considerations on transformation (1984–2018) of kampung and rumah kampung in Surabaya
Authors: Furuta Rikako , Yamagishi Teruki , Shinozaki Kenichi , Hirota Naoyuki , Funo Shuji 
Published: October 2022

AbstractThis paper clarifies the changes in kampungs and their houses (rumah kampungs) over the past 35 years based on field surveys of three kampungs in Surabaya, Indonesia, conducted in 1983/84, 2006, and 2016–2018. The major objective is to develop new policies for the Kampung Improvement Program (KIP) and public housing. The main finding is that most of the kampungs have maintained their basic spatial structure and community organization, although the houses themselves have been transformed. Thus, kampungs in Surabaya continue to maintain their unique characteristics.
Influence of rye/oat cover crop in a two‐year soybean production system
Authors: Overmyer Keeley , Looker Wayde , Dorrance Anne E. , Tilmon Kelley J. , Lindsey Laura E. 
Published: October 2022

AbstractAs the cost of corn (Zea mays L.) production increases, some farmers find continuous soybean [Glycine max (L.) Merr.] to be more profitable than corn–soybean rotation. However, a grass cover crop could help diversify the cropping system. The study objectives were to evaluate planting date and termination timing of a rye (Secale cereale L.)/oat (Avena sativa L.) cover crop mix on cover crop biomass and soybean disease, insects, slugs, and grain yield within a 2‐yr soybean production system. Field trials were conducted in 2018 and 2019 at two locations in Ohio (northwestern and western). The main plot factor was cover crop planting date (September through October) and the subplot factor was cover crop termination timing (2 and 4 wk prior to soybean planting). Cover crop planting date and termination timing had little influence on soybean diseases and insects. Soybean grain yield was influenced by cover crop termination timing at the northwestern location. In 2018, soybean yield was 4% greater when the preceding cover crop was terminated late and in the control (no cover crop) compared to early cover crop termination. The following year, soybean yield was 8% greater when the cover crop was terminated late compared to early termination and the control. At the western location, there was no impact of cover crop termination timing on yield. Late‐terminated cover crops had a positive effect or no effect on yield of the following soybean crop.
Hajdu‐Cheney syndrome with atypical cardiovascular abnormalities
Authors: Ekure Ekanem N. , Sokunbi Ogochukwu , Kruszka Paul , Muenke Maximilian , Adeyemo Adebowale A. 
Published: October 2022

AbstractHajdu‐Cheney syndrome is an ultra‐rare autosomal dominant disorder caused by a heterozygous variant in NOTCH2 gene. Characteristic features include osteolysis, distinct facial appearance, skull deformity, joint laxity, osteoporosis, and short stature. Associated abnormalities are congenital heart disease, congenital defects of the kidney, and neurological problems. Here, we present the first reported case of an African child with a variant in NOTCH2 gene and features of Hajdu‐Cheney syndrome in whom we detected a congenital heart defect that has not been previously reported in association with the syndrome. To appropriately characterize this disease and document correct proportion of cardiovascular malformation associations, echocardiography is recommended for all cases of Hajdu Cheney syndrome.
Guidelines in Practice: Prevention of Unintentionally Retained Surgical Items
Authors: Cochran Karen 
Published: October 2022

ABSTRACTRetained surgical items (RSIs) are adverse events that can affect patients, surgeons, and nurses. Interdisciplinary teams should work to standardize surgical item accounting processes and help all perioperative team members prevent RSIs. AORN recently revised the “Guideline for prevention of unintentionally retained surgical items,” which provides background information on RSIs and ways to prevent them. The revised guideline describes the role of team communication coupled with specific nursing actions aimed at preventing RSIs. This article reviews key concepts from the guideline and discusses new or changed recommendations regarding a consistent interdisciplinary approach and standard counting procedure; accounting for soft goods, sharps and miscellaneous items, instruments, device fragments and explants, and foam pieces; reconciling count discrepancies; adjunct technology; and education. The article also provides a scenario related to implementing adjunct technology to prevent RSIs. Perioperative leaders and nurses should review the guideline in its entirety and apply the recommendations to prevent RSIs.
Vereinfachte Berücksichtigung der Rahmentragwirkung in Mauerwerksgebäuden
Authors: Kubalski Thomas , Butenweg Christoph , El‐Deib Khaled 
Published: October 2022

AbstractAufgrund der gestiegenen Anforderungen durch höhere Einwirkungen aus Wind und Erdbeben ist eine Verbesserung und Optimierung der Berechnungs‐ und Bemessungsansätze für Mauerwerksbauten erforderlich. Eine bessere Ausnutzung der Tragwerksreserven ist durch die Berücksichtigung der Rahmentragwirkung mit einer Aktivierung der Deckenscheiben in den Rechenmodellen möglich, die in der Praxis aufgrund der Komplexität der Wand‐Decken‐Interaktion bislang nicht ausgenutzt wird. Im vorliegenden Aufsatz wird ein vereinfachter Ansatz auf Grundlage der mitwirkenden Plattenbreite von Schubwänden aus Mauerwerk vorgestellt, der die wesentlichen Einflussfaktoren in parametrisierten Tabellen erfasst. Damit steht den Tragwerksplanern ein einfach anwendbares Werkzeug zur Verfügung, um die Rahmentragwirkung in der Mauerwerksbemessung anzusetzen.
The antitumor activity and pharmacokinetics research of PPD‐Arg (Tos) using ultra‐performance liquid chromatography‐quadrupole‐time‐of‐flight mass spectrometry
Authors: Liu Jiayin , An Yang , Su Jun , Dong Qinghai , Xie Hongliu , Liu Jihua 
Published: October 2022

AbstractIn this study, a new compound PPD‐Arg (Tos) (PAT), an arginine derivative of 20(s)‐PPD, was synthesized via Fmoc‐Arg (Tos)‐OH and 20(s)‐PPD. The pharmacokinetic properties in rats, in vitro cytotoxicity, and cell apoptosis rates of protopanaxadiol (PPD) and PAT were determined. A sensitive bioanalytical method for pharmacokinetics using ultra‐performance liquid chromatography coupled with time‐of‐flight mass spectrometry was developed and validated. The result showed that the Tmax and t1/2 of PAT were significantly enhanced, indicating a long‐lasting effect in vivo. Compared to the PPD group, the PAT group showed higher bioavailability. PAT also exhibited higher antitumor efficacy than PPD against three cancer cells, especially the strongest inhibitory activity against Huh‐7, even more potent than the positive control of paclitaxel. Therefore, the apoptosis assay based on annexin V/propidium iodide–combined staining against Huh‐7 further demonstrated that PAT could induce apoptosis of Huh‐7 cells. Better pharmacokinetic properties and antitumor efficacy of the arginine derivative of 20(s)‐PPD were important. These findings could provide references for further clinical research on amino acid derivatives of PPD as antitumor agents.
Cyclophilin A‐mediated mitigation of coronavirus SARS‐CoV‐2
Authors: Sekhon Simranjeet Singh , Shin Woo‐Ri , Kim Sang Yong , Jeong Dong‐Seok , Choi Wooil , Choi Bong‐Keun , Min Jiho , Ahn Ji‐Young , Kim Yang‐Hoon 
Published: October 2022

AbstractHuman cyclophilin A (hCypA) is important for the replication of multiple coronaviruses (CoVs), and cyclosporine A inhibitors can suppress CoVs. The emergence of rapidly spreading severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) variants has sparked concerns that mutations affect the binding ability of the spike (S) protein to the angiotensin‐converting enzyme 2 (ACE2) cell receptor, affecting the severity of coronavirus disease (COVID‐19). Far‐western blotting and surface plasmon resonance (SPR) results revealed that hCypA interacts strongly with the viral SARS‐CoV‐2 receptor‐binding domain (RBD), with a binding affinity of 6.85 × 10−8 M. The molecular interaction between hCypA and the viral protein interface was shown using three‐dimensional structural analysis, which revealed the blocking of key residues on the RBD interface by hCypA. The RBD facilitates binding to the ACE2 receptor. The hCypA–S protein complex suppressed the binding of RBD to the ACE2 receptor, which a required event for CoV entry into the host cell. The reliability of this postulated blocking mechanism of the hCypA–SARS‐CoV2 RBD complex with ACE was confirmed by SPR and molecular interaction lateral flow (MILF) strip assay, which offers the immunochromatographic signal read‐outs. The emergence of new SARS‐CoV‐2 variants with key mutations in RBD had a negligible effect on the binding of the RBD variants to hCypA, indicating an effective mitigation strategy for SARS‐CoV‐2 variants. The MILF strip assay results also highlight the neutralizing effect of hCypA by effectively blocking RBD (wild type and its variants) from binding ACE2. Given the importance of hCypA in viral entry regulation, it has the potential to be used as a target for antiviral therapy.
The strategy of odor−taste−texture interactions to produce low salt bread: Oral processing and sensory properties
Authors: Faridi Esfanjani Afshin , Mohebbi Mohebbat 
Published: October 2022

AbstractBackground and ObjectivesSince bread consumption has a significant role in enhancing salt intake in the human diet, this study aimed to decrease the salt level in bread while maintaining its desirable properties. The strategy of odor−taste−texture interactions was used to reduce the 50% NaCl level of the bread, in which gel emulsifier was a texture agent, cheese odor was an odor agent, and monosodium glutamate (MSG) and NaCl were taste substances. Bread characterizations (i.e., texture, structure, and mastication), properties of the bolus (i.e., texture and particle size distribution), and the sensory properties of low salt bread were investigated.FindingsBread samples with lower porosity had a denser structure, resulting in higher hardness. The low salt bread samples, formulated with a gel emulsifier (1% of flour weight), showed lower hardness and higher porosity (%). The bread samples with higher springiness needed a longer chewing time. The bread samples with larger air cell sizes resulted in bolus with smaller particle sizes. According to sensory analysis the interactions of gel emulsifier with taste in the bread matrix increased porosity and softness perception.ConclusionsOdor−taste−texture interactions were an appropriate strategy to improve some of the sensory properties of low‐salt bread samples, such as increasing porosity, bread flavor, and softness.Significance and NoveltyThe present study investigated the impact of cheese odor‐NaCl‐MSG interactions combined with a gel emulsifier on the flavor and texture characterization of low salt bread.