bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between time to emergency neurosurgery and clinical outcomes for spontaneous hemorrhagic stroke: A nationwide observational study
Authors: Kim Ki Hong , Ro Young Sun , Park Jeong Ho , Jeong Joo , Shin Sang Do , Moon Sungwoo 
Published: April 2022

Objective
Spontaneous hemorrhagic stroke is a devastating disease with high mortality and grave neurological outcomes worldwide. This study aimed to evaluate the association between the elapsed time from emergency department (ED) visit to emergency neurosurgery and clinical outcomes in patients with spontaneous hemorrhagic stroke.

Methods
A nationwide cross-sectional study was conducted using the nationwide emergency database in Korea. Spontaneous hemorrhagic stroke patients who received neurosurgery within 12 hours of ED visit between January 2018 and December 2019 were enrolled. The main exposure was time to neurosurgery and the primary outcome was in-hospital mortality. Multivariable logistic regression was conducted.

Results
Among 2,602 study populations (incidence rate: 2.5 per 100,000 person-years, 15.8% of SAH, 78.6% of ICH, and 5.6% of mixed type), 525 (20.2%) patients received surgery in the ultra-early (0–2 hours) group, 1,093 (42.0%) in the early (2–4 hours) group, and 984 (37.8%) in the late (4–12 hours) group. The early group showed better survival outcomes than the ultra-early and late group (in-hospital mortality 22.2% vs. 26.5% and 26.1%, p = 0.06). Compared to the late group, adjusted OR (95% CI) for in-hospital mortality was 0.78 (0.63–0.96) for the early group, while there was no significant difference in the ultra-early group (0.90 (0.69–1.16)).

Conclusions
Early neurosurgery within 2–4 hours of the ED visit was associated with favorable survival outcomes in patients with spontaneous hemorrhagic stroke.
Fundamentos e Práticas para o Ensino de Ciências – Curso Licenciatura Indígena Guarani - Pedagogia
Authors: Pereira Yara Christina Cesário 
Published: April 2022

O objetivo desse ensaio é apresentar experiências didáticas vivenciadas junto ao grupo do 5º período da disciplina de Fundamentos e Práticas para o Ensino de Ciências do Curso de Licenciatura Indígena Guarani — Habilitação Pedagogia – UNIVALI configurando a docência a partir da percepção indígena, valorizando os saberes, os sabores e os fazeres tradicionais da aldeia/comunidade e, ao mesmo tempo, vislumbrando possibilidades de dialogar com o Currículo Base da Educação Infantil e do Ensino Fundamental do Território Catarinense - CBTC (2019). Os(as) protagonistas são os(as) 18 acadêmicos(as) que, ao trazerem as vozes das suas aldeias, nos conectam com os princípios essenciais: o respeito ao universo, aos ciclos naturais e a terra onde tudo nasce. A perspectiva intercultural possibilitou enxergar, como interdependentes, a singularidade na diversidade e o seu contrário. Evidenciou, também, a boniteza da multidimensionalidade de culturas e a riqueza da integração de práticas para o ensino de Ciências que podem ser complementares. Enxergar com o olhar de uma cultura, a cultura do outro. Olhar com o olhar que repara, pois reparar é “por em bom estado”. Esse é o exercício que deve ser vivenciado por professores(as) das escolas indígenas e não indígenas.
What If Educational Inquiry Were Neither a Social Science Nor a Humanities Field? Revisiting Joseph Schawb’s “The Practical” in the Aftermath of the Science Wars
Authors: Donmoyer Robert 
Published: April 2022

The recent debates about what constitutes scientific research in Education, on the one hand, and the so-called “paradigm wars” that got played out in the final quarter of the 20th century, on the other, are more similar than different. At the center of both controversies was the relative worth of quantitative and qualitative research methods. Both controversies also distracted researchers’ from addressing the substantive problems that plague schools and other educational organizations. This paper attempts to move the field beyond the debates of the past and similar debates that seem likely to occur in the future. Inspired, in large part, by Joseph Schwab’s largely unheeded critique of the curriculum field in the late 1960s and early ‘70s, the paper attempts to re-conceptualize what inquiry in a field like Education should look like, as well as the role that quantitative, qualitative, and mixed-methods research could play in a re-conceptualized approach to inquiry.
TRANSPORTATION MODE CHOICE AND OBESITY: A CROSS-SECTIONAL STUDY AT SENIOR HIGH SCHOOL FEMALE STUDENT IN YOGYAKARTA, INDONESIA
Authors: Mizwar Michdarul , Astiti Dewi , Aji Arif Sabta , Siswati Tri 
Published: April 2022

Background: The prevalence of obesity has increased worldwide. Indonesia has also experienced a similar rising trend in obesity, especially in adolescents. The current phenomena is shifting mode of transportation from active to passive.Objective: The objective of the study was to determine the correlation between transportation mode and obesity in high school adolescents in Yogyakarta, Indonesia.Methods: A cross-sectional study was created and a total of 238 adolescent girls in class XI from all high schools/equivalents in Bantul, Yogyakarta Province, Indonesia was recruited. Data were collected in February-May 2017. Data characteristics, duration and mode of transportation were collected using a structured questionnaire. In addition, body mass index measured to determine obesity. A logistic regression analysis was performed using SPSS version 20.0.Results: Subjects who used passive transportation mode had a risk of having obesity (OR 5.63, 95% CI: 1.71-8.52). Furthermore, passive transport duration >15 minutes increased the risk of obesity (OR 2.51, 95% CI: 1.07-5.99), while active transport >15 minutes was a protective factor (OR: 0.21 95% CI: 0.19-0.89).Conclusions: There were correlation between the type and duration of the transportation mode used with obesity in adolescent girls.
Climate Change Implications for the Public Finances and Fiscal Policy: An Agenda for Future Research and Filling the Gaps in Scholarly Work
Authors: de Mello Luiz , Martinez-Vazquez Jorge 
Published: April 2022

Abstract
Climate change will pose a major challenge for humanity in future decades. Central to the policy debate are its implications for the public finances and the conduct of fiscal policy more generally. This editorial outlines the budgetary effects, the regulatory and standard-setting challenges, internal governmental organisational changes, and the resource reallocation implications of policies to control climate change and their efficient implementation. The scope for further work – both theoretical and empirical – to bridge existing gaps in the related economics literature is then discussed. Finally, the editorial outlines research questions and first steps on an agenda for policy-relevant research.
Assessment of climatic conditions for tourism in Xinjiang, China
Authors: Cao Kaijun , Gao Jun 
Published: April 2022

Abstract
Tourism is a highly climate-sensitive sector, and the suitability of climate and weather can be a central motivation for travel. Through the tourism climate index (TCI), this study uses daily data from the period of 1980 to 2014 to identify the spatial and temporal distribution of climatic conditions in Xinjiang of China with regard to its climatic attractiveness for general tourism. The analytical results indicate that the climatic conditions of the most suitable months for tourism in Xinjiang are April, May, September, and October. The best climatic condition (TCI > 80) for tourism activities is found in September in most parts of Xinjiang, except for central Tianshan and Turpan Basins. The climate is not attractive for tourism in Xinjiang during the winter months. The annual average number of climatically suitable days (TCI > 70) are the highest in northwestern Aksu, most parts of Kashgar, and western Hotan. Most parts of northern Xinjiang are favorable for summer travel, with high TCI scores and a high average number of climatically suitable days. By contrast, tourist areas in southern and eastern Xinjiang have favorable climatic conditions during Spring and Autumn. These results can provide useful information to both tourists and the tourism industry.
First report of biocellulose production by an indigenous yeast,Pichia kudriavzeviiUSM-YBP2
Authors: Jasme Nurshafiqah , Elangovan Jananisri , Mohd Yahya Ahmad Ramli , Md Noh Nur Asshifa , Bustami Yazmin 
Published: April 2022

AbstractHerein, we describe the first report ofPichiastrain producing biocellulose (BC). This yeast was isolated from rotten pineapple and was identified asPichia kudriavzeviiUSM-YBP2 using 18S rDNA analysis. The formation of pellicle was characterized using a scanning electron microscope (SEM). Based on SEM analysis, pellicles are presented as an interwoven network of fibers. Next, to produce high BC, optimization was conducted using different carbon and nitrogen sources, carbon and nitrogen concentrations, inoculum size, and cultivation condition. The optimized parameters for maximum BC production were as follows: glucose 8.0% (w/v), peptone 2.0% (w/v), yeast extract 0.5% (w/v), disodium phosphate 0.270% (w/v), citric acid 0.115% (w/v), ethanol 0.5% (v/v), and inoculum size 10% (v/v). The production yield is 12.24 ± 0.43 g/L and the productivity of 0.128 g/L/h. Then, BC was further treated using sulfuric acid to destructuring to bionanocellulose (BNC) and was characterized using the transmission electron microscope (TEM), attenuated total reflection-Fourier transform infrared spectroscopy, and X-ray diffraction (XRD) analysis. After acid hydrolysis treatment, BNC showed a spherical shape as in TEM. Interestingly, BNC characteristic band displayed high similarity with cellulose from other bacterial species. Moreover, BNC showed high crystallinity index (∼82%) as estimated using XRD. Thus, our findings substantiated that strain USM-YBP2 showed remarkable BNC production with unique BNC property that can be further explored in various applications.
Thermal ageing performance evaluation of TUK and Nomex-910 papers in natural monoesters
Authors: Mengounou Ghislain Mengata , Boyekong Gerard Ombick , Nkouetcha Emeric Tchamdjio , Imano Adolphe Moukengue 
Published: April 2022

AbstractThis paper is devoted to a comparative analysis of thermal ageing tests of Thermally Upgraded Kraft (TUK) and Nomex-910 papers dipped in palm kernel oil methyl ester (MEPKO), at 110, 130, and 150 °C, for 96 h each. After ageing, paper breakdown voltage (BDV), oils’ dissipation factor, dielectric constant and oxidation stability were determined. Nomex’s BDV was greater than TUK BDV. However, the dissipation factor of the Nomex samples is slightly higher than that of TUK, and the dielectric constant has the opposite behaviour. In addition, the decay content of Nomex/MEPKO was greater than with TUK/MEPKO. These experimental findings indicate that Nomex can be mainly used in high voltage, and TUK in medium voltage power transformers respectively, to allow judicious use of their individual characteristics and money savings.
Exosomal hsa_circ_0000519 modulates the NSCLC cell growth and metastasis via miR-1258/RHOV axis
Authors: Wang Rui , Liu Hongliu , Dong Mingqiang , Huang Dan , Yi Jun 
Published: April 2022

Abstract
This study aims to explore the function and mechanism of exosomal circ_0000519 in non-small cell lung cancer (NSCLC) development. Expression of circ_0000519, microRNA (miR)-1258, and Ras homolog gene family V (RHOV) in serum samples of NSCLC patients or cell lines were examined via quantitative reverse transcription-polymerase chain reaction and Western blotting. The function of circ_0000519 was evaluated through 5-ethynyl-2′-deoxyuridine (EdU) staining, colony formation, transwell, Western blotting, xenograft, and immunohistochemistry analyses. The binding relationship was evaluated by a dual-luciferase reporter assay and RNA pull-down assay. Results showed that circ_0000519 abundance was enhanced in the serum samples of NSCLC patients and cells. circ_0000519 knockdown suppressed the cell growth by decreasing the colony-formation ability and Cyclin D1 expression and inhibited cell metastasis via reducing migration, invasion, and levels of Vimentin and matrix metalloproteinase 9 (MMP9). circ_0000519 overexpression promoted cell growth and metastasis. circ_0000519 was carried by exosomes and knockdown of exosomal circ_0000519 suppressed the cell growth and metastasis. miR-1258 was downregulated in NSCLC cells and targeted by circ_0000519. RHOV was targeted by miR-1258 and upregulated in the NSCLC cells. miR-1258 knockdown or RHOV overexpression attenuated the influence of exosomal circ_0000519 knockdown on cell growth and metastasis. Exosomal circ_0000519 knockdown decreased xenograft tumor growth. Collectively, the knockdown of exosomal circ_0000519 repressed the cell growth and metastasis in NSCLC through the miR-1258/RHOV axis, which provided a new insight into NSCLC development and treatment.
miR-455-5p enhances 5-fluorouracil sensitivity in colorectal cancer cells by targeting PIK3R1 and DEPDC1
Authors: Lou Tingting , Zhang Luqing , Jin Zongshan , Miao Chundi , Wang Jinqiu , Ke Kongliang 
Published: April 2022

Abstract
Our previous study has demonstrated that miR-455-5p was a tumor suppressor in colorectal cancer (CRC). This study aimed to investigate the role of miR-455-5p in 5-fluorouracil (5-Fu) in CRC. The expression of miR-455-5p, PIK3R1, and DEPDC1 was analyzed in HT-29 cells after treatment with different concentrations (0, 0.5, 2.5, and 12.5 μM) of 5-Fu. The effects of miR-455-5p on cell proliferation and apoptosis were analyzed by CCK-8 and flow cytometry. PIK3R1 and DEPDC1 were overexpressed to measure the mechanism of miR-455-5p on 5-Fu sensitivity. And the direct binding between miR-455-5p and DEPDC1 was detected by a dual-luciferase reporter assay. We found that miR-455-5p decreased, while PIK3R1 and DEPDC1 increased after 5-Fu treatment. miR-455-5p mimic significantly suppressed cell viability and elevated cell apoptosis in 5-Fu-treated HT-29 cells, whereas miR-455-5p inhibitor showed the opposite effects. Overexpression of PIK3R1 and DEPDC1 could attenuate the effects of miR-455-5p mimic on the viability and apoptosis of 5-Fu-treated cells. miR-455-5p could directly bind to DEPDC1 in HT-29 cells. In conclusion, miR-455-5p enhanced 5-Fu sensitivity by targeting PIK3R1 and DEPDC1 in CRC. This study provides a novel role of miR-455-5p in CRC and restoring miR-455-5p might be a therapeutic strategy to enhance chemosensitivity to 5-Fu.
Matrix eigenvalue solver based on reconfigurable photonic neural network
Authors: Liao Kun , Li Chentong , Dai Tianxiang , Zhong Chuyu , Lin Hongtao , Hu Xiaoyong , Gong Qihuang 
Published: April 2022

Abstract
The solution of matrix eigenvalues has always been a research hotspot in the field of modern numerical analysis, which has important value in practical application of engineering technology and scientific research. Despite the fact that currently existing algorithms for solving the eigenvalues of matrices are well-developed to try to satisfy both in terms of computational accuracy and efficiency, few of them have been able to be realized on photonic platform. The photonic neural network not only has strong judgment in solving inference tasks due to the superior learning ability, but also makes full use of the advantages of photonic computing with ultrahigh speed and ultralow energy consumption. Here, we propose a strategy of an eigenvalue solver for real-value symmetric matrices based on reconfigurable photonic neural networks. The strategy shows the feasibility of solving the eigenvalues of real-value symmetric matrices of n × n matrices with locally connected networks. Experimentally, we demonstrate the task of solving the eigenvalues of 2 × 2, 3 × 3, and 4 × 4 real-value symmetric matrices based on graphene/Si thermo-optical modulated reconfigurable photonic neural networks with saturated absorption nonlinear activation layer. The theoretically predicted test set accuracy of the 2 × 2 matrices is 93.6% with the measured accuracy of 78.8% in the experiment by the standard defined for simplicity of comparison. This work not only provides a feasible solution for the on-chip integrated photonic realization of eigenvalue solving of real-value symmetric matrices, but also lays the foundation for a new generation of intelligent on-chip integrated all-optical computing.
Perforated steel block of realizing large ductility under compression: Parametric study and stress–strain modeling
Authors: Zhou Yingwu , Zhuang Li , Hu Zhiheng , Hu Biao , Huang Xiaoxu , Li Shan , Guo Menghuan , Zhu Zhongfeng 
Published: April 2022

Abstract
On one hand, the nature of linear elastic up to brittle rupture hinders the application of fiber-reinforced polymer (FRP) bars as reinforcement in the concrete member due to the displacement ductility demand of structures. On the other hand, FRP bars are equipped with many irreplaceable advantages as reinforcement in concrete structures. To resolve this contradiction, a possible solution is to use the so-called compression yield (CY) structural system and the ductility of a concrete beam incorporating a CY system comes from the compressive side rather than the tensile side. Thus, the development of material in the compressive side (CY material) with well-designed mechanical properties (strength, stiffness, and ductility) is a key challenge. In this study, the CY material is developed by perforating the mild steel block and then substantiated by the test results. Then, experimentally calibrated finite element models are used to conduct systematic parametric studies, based on which parametric equations are proposed to predict the stiffness and ultimate strength of the CY material. Finally, theoretical constitutive models are developed to predict the stress–strain response of perforated steel block under compression and a reasonably acceptable agreement is reached between the model predictions and the test results.
High Altitude Pulmonary Edema, High Altitude Cerebral Edema, and Acute Mountain Sickness: an enhanced opinion from the High Andes – La Paz, Bolivia 3,500 m
Authors: Zubieta-Calleja Gustavo R. , Zubieta-DeUrioste Natalia 
Published: April 2022

AbstractTraveling to high altitudes for entertainment or work is sometimes associated with acute high altitude pathologies. In the past, scientific literature from the lowlander point of view was primarily based on mountain climbing. Sea level scientists developed all guidelines, but they need modifications for medical care in high altitude cities. Acute Mountain Sickness, High Altitude Pulmonary Edema, and High Altitude Cerebral Edema are medical conditions that some travelers can face. We present how to diagnose and treat acute high altitude pathologies, based on 51 years of high altitude physiology research and medical practice in hypobaric hypoxic diseases in La Paz, Bolivia (3,600 m; 11,811 ft), at the High Altitude Pulmonary and Pathology Institute (HAPPI – IPPA). These can occasionally present after flights to high altitude cities, both in lowlanders or high-altitude residents during re-entry. Acute high altitude ascent diseases can be adequately diagnosed and treated in high altitude cities following the presented guidelines. Treating these high-altitude illnesses, we had no loss of life. Traveling to a high altitude with sound medical advice should not be feared as it has many benefits. Nowadays, altitude descent and evacuation are not mandatory in populated highland cities, with adequate medical resources.
A new strategy for cathodic protection of steel in fresh water using an aluminum electrode as an impressed current anode: a case study
Authors: Deyab Mohamed A. , Al-Qhatani Mohsen Mohammed 
Published: April 2022

Abstract
In fresh water, aluminum cannot be used as a galvanic anode for the cathodic protection (CP) system because the accumulation of oxide films causes the electrochemical potential to change to an extremely noble potential (passivation). To work correctly, aluminum anodes often require chloride ions in the electrolyte. Because impressed current anodes are fairly inert, the anode component corrodes at an extremely low rate. The present case study focused on a novel strategy for employing aluminum anode as an impressed current anode for cathodic protection inside a fresh water storage tank made of X65 steel. According to the impressed current scenario, 0.6 A of current supply and 0.33 V of voltage were required to properly protect the X65 steel tank’s internal surface area of 421 m2. Prior to the implementation of cathodic protection, the potentials varied from −0.474 to −0.509 V (vs. Ag/AgCl). After 30 days, 60 days, and 90 days of cathodic protection, the potential values inside the protection zone showed a significant change (−0.800 and −1.150 V vs. Ag/AgCl). The results demonstrate that aluminum anodes with a considerable performance (current capacity) and a minimal consumption level can really be employed as impressed current anodes in fresh water applications.
Residual Strength of Liquefied Soil: The Effect of Induced Partial Saturation
Authors: Gates Ian D. , Ghayoomi Majid 
Published: April 2022

Abstract
Post-liquefaction response and residual strength play important roles in stability assessment of liquefied ground. Considering the recent advancements in the application of induced partial saturation for liquefaction mitigation, the state of knowledge in estimating the residual strength should be extended for liquefied desaturated soils. In this paper, the residual strength response of a clean sand at different saturation levels was investigated using a ring shear device. Direct air injection was used to desaturate the soil, which helped with mitigating the liquefaction under cyclic loading. However, by raising the shear strain level, both saturated and partially saturated soils were liquefied, followed by residual strength measurement. Results indicate that the residual strength increased with a reduction of the saturation level because of the change in compressibility and consequent volume reduction. In addition, the strain-rate dependency of the residual strength was confirmed because an increase of shear strain rate resulted in an increase in residual strength under both saturated and partially saturated conditions.
Colonial Galant: Three Analytical Perspectives from the Chiquitano Missions
Authors: Grant Roger Mathew 
Published: April 2022

Abstract
During the eighteenth century, a vibrant tradition of choral and orchestral music flourished among the Chiquitano Indigenous people. Coerced into entering Jesuit missions in the Spanish Viceroyalty of Peru (now eastern Bolivia) the Chiquitano first heard and then began to make music in a European style. Archival sources preserve several operas and large-scale liturgical compositions written entirely in the Chiquitano language and attributed to Indigenous composers. Unlike the heavy counterpoint of other New World sacred music, this repertoire is characterized by simple harmonies, regular cadence patterns, and transparent textures. In three analytical vignettes, this article explains how the galant style of this mission music helped to achieve the colonial aims of European settlers. Previous scholars have generally celebrated the exceptional status of this unusual body of music and pointed to it as proof of an isolated set of instances in which traditional power hierarchies between colonizers and Indigenous colonized were unstable. Drawing on Brian Larkin, Homi Bhabha, and Franz Fanon, this article by contrast suggests that the specific aesthetic forms produced by the Chiquitano were vital in helping to shape them as colonial subjects. The galant style of their music was both easy to participate in and impressive to experience. Taking this seriously means rewriting our European narrative of the galant and retelling it, in part, as one of cultural imperialism and colonial hegemony.