bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of nonoxynol-9 (N-9) on sperm functions: systematic review and meta-analysis
Authors: Xu Murong , Zhao Mingpeng , Li Raymond Hang Wun , Lin Zhixiu , Chung Jacqueline Pui Wah , Li Tin Chiu , Lee Tin-Lap , Chan David Yiu Leung 
Published: February 2022

Objective
To summarize the currently available phase I and II clinical trials of the effects of nonoxynol-9 (N-9) on human sperm structure and functions.

Methods
A systematic review and meta-analysis aiming to evaluate the spermicidal activity of N-9 on motility, was conducted in PubMed, EMBASE, and Cochrane databases by 10 March 2021. The counted numbers of progressive motile (PR) sperm in cervical mucus and the vanguard sperm penetration distances were analyzed. Other effects on sperm structures and physiological activities were reviewed as well.

Results
In the pooled results, percentages or counted numbers of PR sperm decreased after the treatment of N-9. Vanguard sperm penetration distance was shortened in treated groups. N-9 has been confirmed to damage the structures of sperm, as well as other organelles like acrosome and mitochondria. The physiological activities such as generation of reactive oxygen species, superoxide dismutase activity, acrosin activity, and hemizona binding were all inhibited in the reviewed studies.

Conclusions
N-9 has several impacts on sperm owing to its potency in reducing sperm motility and cervical mucus penetration, as well as other functional competencies.

Lay summary
Nonoxynol-9 (N-9) has been used worldwide as a spermicide to kill sperm for more than 60 years but can cause side effects including vaginal irritation and can increase the rate of contraceptive failure. A detailed analysis of published literature aiming to evaluate the spermicidal activity of N-9 on sperm was carried out. In the pooled results, N-9 reduced the number of active sperm and the distance they traveled. It also caused damage to the structures of sperm and to the way the sperm acted and interacted with the egg. In conclusion, N-9 impacts on sperm in a number of ways that lead to sperm death and dysfunction.
CARACTERIZACIÓN Y DISMINUCIÓN EN LA EXPRESIÓN DE UNA QUITINA SINTASA MEDIADA POR ARNi EN Hypothenemus hampei (CURCULIONIDAE)
Authors: Ossa Ossa Gustavo Adolfo , Villegas Estrada Bernardo , Valencia Jiménez Arnubio 
Published: February 2022

La broca del café, Hypothenemus hampei, es un insecto plaga que causa daños significativos al grano de café y grandes pérdidas económicas a los productores en todo el mundo. Al igual que otros insectos, la broca de café requiere de quitina sintasas (CHS) para la biosíntesis de la quitina, componente principal del exoesqueleto del insecto, y de vital importancia para su crecimiento y desarrollo. En este estudio, el gen CHS1 de la broca del café (HhCHS1) fue identificado, caracterizado y posteriormente silenciado mediante el uso de ARNi, mecanismo que permite degradar el ARNm e interrumpir la expresión de proteínas de interés en un organismo. Los perfiles de expresión del gen HhCHS1, medidos por RT-qPCR, mostraron niveles de expresión diferencial en las diferentes etapas del desarrollo del insecto. Los niveles más altos de expresión se encontraron en larvas de segundo estadio (L2) y machos adultos. El ARNcd administrado por vía oral, a concentraciones de 2 µg/100 µL, generó un silenciamiento efectivo del gen HhCHS1 (84 %) después de 7 días de tratamiento. Estos resultados sugieren que el gen HhCHS1 desempeña un papel importante en el desarrollo del insecto, y que, por ende, podría usarse como objetivo para desarrollar nuevas estrategias de manejo de este insecto plaga, mediante el uso de ARNi. Palabras Clave: ARNcd, café, insecto plaga, quitina-sintasa, RT-qPCR.
Paternalism vs. autonomy? Substitute and supported decision-making in England and Hungary
Authors: Szerletics Antal 
Published: February 2022

AbstractThis paper explores substitute and supported decision-making in the light of the UN Convention on the Rights of Persons with Disabilities (CRPD). The CRPD, adopted by the UN General Assembly in 2006, introduces a ‘paradigm shift’ in the regulation of legal capacity by endorsing the idea of universal legal capacity, i.e. that everyone, including persons with disabilities ‘enjoy legal capacity on an equal basis with others’. After examining the conceptual and regulatory issues surrounding substitute and supported decision-making and the requirements of the CRPD and the first General Comment of the UN Committee on the Rights of Persons with Disabilities (GC1), the paper proceeds to examine the regulations of the Mental Capacity Act 2005 (England & Wales) and the Hungarian Civil Code and their (non-)compliance with the CRPD and GC1.
Assessment of Adherence of Public and Private Universities to Examination Regulatory Frameworks in Mount Kenya Region
Authors: Mulongo Meshack Ambani 
Published: February 2022

The study focused on the assessment of the adherence of public and private universities to examination regulatory frameworks in Mount Kenya region. The objectives of the study were to: assess the extent to which universities in Mount Kenya region adhere to examination regulatory frameworks, and examine the significant differences between public and private universities levels of adherence to examination regulatory frameworks in Mount Kenya region. Descriptive research design was used. The study sampled 380 university students using Kathuri and Pals’ (1999) sampling table. Self-constructed questionnaires were used to collect data from students and university examination officers and an interview schedule from registrars. Data was analyzed descriptively by use of means, percentages and frequencies; and inferentially by computation of a t-test. Results indicated that majority of universities did not adhere to regulatory frameworks as indicated by 51.3% of respondents, students were congested in examination rooms as reflected by 47.7% of subjects, and there was weakness in identification of examinees as they entered examination rooms as shown by 55.7% of respondents. The t-test yielded a p-value of 0.887 against the α value of 0.05; hence, the null hypothesis was supported (at α =.05) and concluded that the adherence to regulatory framework for private and public universities was largely the same. The study concluded that university students did not adhere to regulatory frameworks, there was no proper spacing of students in examination rooms, and there was weakness in identification of students as they entered examination rooms. The study also found that students did not borrow materials in examination rooms, and they were not allowed to talk during examinations. Implications of the study were: both public and private universities should ensure adherence to regulatory frameworks, avail sufficient spacing in examination rooms, and ensure proper identification of students as they enter examination rooms. Results will be referred to by education policy makers to improve the management of examinations in universities.
The Relationship Between Peer Social Support and Academic Resilience of Young Adult Migrant Students in Jakarta
Authors: Putri Wening Cahya , Nursanti Ade 
Published: February 2022

The more severe academic and psychosocial problems make young adult migrant students tend to have academic resilience to avoid psychological distress which could adversely affect their academic performance. One of the factors that help students to become resilient is protective factors, namely social support from the closest environment. Being away from family and relatives makes peers become the most intimate environment for young adult migrant students. Another consideration is that undergraduate young adult migrant students are at the stage of development where peers have a crucial role at this stage development. Based on this phenomenon, the present study is aimed to find out whether there is a correlation between peers’ social support and academic resilience among young adult migrant students. Social support itself is divided into two main categories: assistance related and non-assistance related. Participants in this study were 101, 17-25-year-old migrant students with at least 6-month experience studying in Jakarta and living without their parents. The research used a quantitative non-experimental method, employing the questionnaire of Social Provisions Scale and Academic Resilience Scale. The results of the correlation test (Spearman test) indicated that there was a significantly positive relationship between peer social support (assistance related r 0.472 (p = 0.00 0.05) and non-assistance related r 0.569 (p = 0.00 0.05)) and academic resilience among young adult migrant students. This result shows that that the higher the social support provided by peers, the higher the academic resilience of young adult migrant students will be.
A Cross-Disciplinary Project-Based Learning to Raise Indonesian Students’ Awareness of Natural Disasters
Authors: Da Silva Anna Marietta , Helnywati Helnywati 
Published: February 2022

The present study aims at raising young students’ awareness of natural disasters through a cross-disciplinary multimodal project-based learning method using Vygotsky’s (1986) socio-cultural approach. An Art project was carried out by second-grade students of one private bilingual school in Jakarta. The project, which was group work, included discussing which objects could save lives from the disaster, drawing the objects, and presenting the work in front of the class. All discussions and presentations were audio recorded. The objects and the recording were then analysed to identify students’ knowledge about surviving three common natural disasters in Indonesia, i.e., earthquake, tsunami, and volcanic eruption. The findings indicate that the students have an initial knowledge about how to survive the disasters, but their literacy on disaster mitigation is still low. It is recommended that literacy on natural disasters should be part of the curriculum and implemented consistently.
Stock price performance of pharmaceutical companies: pre-vaccine COVID-19 - post-vaccine COVID-19
Authors: Vera Ramírez Henry Daniel , Valencia Serna Ferly Antonio 
Published: February 2022

This paper performs an analysis of the behaviour of the shares of the main pharmaceutical companies that research to obtain vaccines with a high degree of efficacy for COVID-19. A multiple regression econometric model is proposed, which relates stock prices to the impact of vaccine development on stock prices, including a dummy variable -over the time series- in the analysis. The results suggest significant associations between some pharmaceutical companies that developed vaccines in record time in the period analysed and an impact on the sector’s earnings performance.
Longitudinal Factorial Invariance of a Brief Measure of Affect and Calm Focus
Authors: Kim Hanjoe , Smoots Kimberly D. , Sajovec Patrick , Rizvi Syed , Esat Gulden , Smith Bradley H. 
Published: February 2022

Abstract
Mindfulness-based practices for school-aged children are increasingly common in the United States. Positive and negative affect are theoretically and empirically associated with school outcomes, and these constructs are likely to be impacted by school-based mindfulness practices. Furthermore, mindful states, such as being calm and focused, targeted by mindfulness-based practices are a potential causal mechanism to improve learning and behavior. This study describes a test of longitudinal factorial invariance for a brief measure of affect states plus a state of calm focus that is appropriate for use in mindfulness intervention studies with elementary school-aged children. Data were collected from 97 fourth-grade students in an urban elementary school that was about 46% Hispanic and 44% White. Students listened to one of six different conditions each day for 24 school days: There were four individual mindfulness modules (cross-connect, pause buttons, belly breathing, and mindful minute), one condition that included all four of the modules together, and one condition that was a control activity (a grade-appropriate story presented via audiorecording). Students provided self-report of positive and negative emotions plus calm focus immediately before and after the presentation of the audio. Results showed high levels of internal consistency for the scales, low correlations between scales, and factorial invariance in the pre- and post-test design for five of the six conditions. These findings support the use of this measure in studies with older elementary school students. Future studies should further document construct validity through external validation of the scales.
Efektivitas Latihan Pliometrik dalam Meningkatkan Power Otot Lengan dan Otot Tungkai Atlet Bolavoli: Literature Review
Authors: Priyoko Ridlo , Januarto Oni 
Published: February 2022

Review literature study to determine the effect of plyometric training on arm and leg muscle power in volleyball athletes based on secondary data or previous research journal articles related to the variables studied. The literature review data collection used the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) flow method. The search refers to data inclusion criteria (1) research variables according to writing needs (2) experimental research collection methods (3) Sinta and Scopus indexed journals (4) credible data analysis. The results of the analysis show that plyometric training variables have an effective effect on increasing arm and leg muscle power in volleyball athletes. There are several plyometric training methods that can be used and will produce a significant impact if the trainer pays attention to the characteristics of each individual and is supported by the appropriate facilities and equipment.
Studi literatur review bertujuan untuk mengetahui efektivitas latihan pliometrik terhadap peningkatan power otot lengan dan otot tungkai atlet bolavoli berdasarkan dari data sekunder atau artikel jurnal penelitian sebelumnya yang terkait dengan variabel diteliti. Pengumpulan data literatur review menggunakan metode alir Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA). Pencarian mengacu pada kriteria inklusi data (1) variabel penelitian sesuai kebutuhan tulisan (2) metode pengumpulan penelitian eksperimen (3) jurnal terindeks Sinta dan Scopus (4) analisis data secara kredibel. Berdasarkan hasil artikel yang analisis menunjukkan bahwa variabel latihan pliometrik berdampak secara efektif guna meningkatan power otot lengan dan otot tungkai pada atlet bolavoli. Terdapat beberapa metode latihan pliometrik yang dapat digunakan dan akan menghasilkan dampak efektif apabila pelatih memperhatikan karakteristik setiap individu serta didukung dengan fasilitas dan peralatan yang sesuai.
Pengembangan Materi Bola Basket Tahap Fundamental Pada Klub Hutama Manggala Basketball Yang Dikemas Dalam E-Modul
Authors: Fatoni Nasrullah , Supriyadi Supriyadi , Widiawati Prisca 
Published: February 2022

This research is motivated by the importance of trainers understanding the aspects that need to be given during training, especially at the Fundamental stage. The purpose of this research is to develop material for the fundamental stage of basketball at the Hutama Manggala Basketball club which is packaged in an E-module. The research method used is Research & Development (R&D) from Borg & Gall. In this study using three methods, namely analysis, validation, and group testing. Data collection is done by using a questionnaire or questionnaire. There are several values ​​from the aspect of suitability, attractiveness, convenience, and usefulness. From the test results, the percentage values ​​obtained are media experts 93.75 percent (very valid), basketball experts 82.76 percent (very valid), basketball coaching experts 87.14 percent (very valid), small group trials 88.03 percent(very valid), a large group trial (very valid) and resulted in the Fundamental stage basketball material containing the history of basketball, facilities and infrastructure in basketball, LTAD Basketball, Abcs training, Athletic Movement, Early Childhood Activities, Psychology early childhood, and videos related to motion and basic techniques in basketball. Based on these results, the fundamental stage basketball material packaged in the E-module is feasible to use.
Penelitian ini dilatarbelakangi dengan pentingnya pelatih memahami aspek-aspek yang perlu diberikan pada saat latihan khususnya di tahap Fundamental. Tujuan dari penelitian ini adalah untuk mengembangkan materi bola basket tahap fundamental pada klub Hutama Manggala Basketballyang dikemas dalam E-modul. Metode Penelitian yang digunakan yaitu Research & Development (R&D) dari Borg & Gall. Dalam penelitian ini menggunakan tiga metode yaitu analisis, validasi serta uji coba kelompok. Pengambilan data dilakukan dengan menggunakan angket ataupun kuesioner. Terdapat beberapa nilai dari aspek kesesuaian, kemenarikan, kemudahan dan kebermanfaatan. Dari hasil pengujian diperoleh nilai persentase yaitu ahli media 93,75 persen (sangat valid), ahli bola basket 82,76 persen (sangat valid), ahli kepelatihan bola basket 87,14 persen (sangat valid), uji coba kelompok kecil 88,03 persen (sangat valid), uji coba kelompok besar (sangat valid) dan dihasilkan materi bola basket tahap Fundamental yang berisi Sejarah bola basket, Sarana dan prasaran pada olahraga bola basket, LTAD Basketball, Abcs training, Athletic Movement, Aktivitas Anak Usia dini, Psikologi anak usia dini, dan video terkait gerak dan teknik dasar pada bola basket . Berdasarkan hasil tersebut maka materi bola basket tahap fundamental yang dikemas dalam E-modul layak untuk digunakan.
Literature Review: Aktivitas Fisik Dan Pola Makan Terhadap Obesitas Peserta Didik Sekolah Dasar
Authors: Amenani Cyvensa , Januarto Oni Bagus 
Published: February 2022

Obesity is a disease that is a big problem in parts of the world, this disease attacks all ages, not only adults but also minors. The writing of this article was carried out because the author's aim was to find out whether there was a relationship between physical activity and diet on obesity in elementary school students. Methods: The author collects articles using the Google Scholar database. The keywords used are physical activity on obesity, diet on obesity, and the effect of physical activity on obesity, diet. Vulnerable years are from 2011 to 2020. The article above uses a correlational research design. Some of the articles reviewed have been indexed by Synta S1-S6 or Scimago Q1-Q4. Results: The author found 23 articles with 20 articles published in national journals and 3 international journals. The results of a review conducted on several articles above show that there is a significant relationship between physical activity, diet, and obesity. Conclusion: After reviewing the article, the author found a relationship between physical activity and diet on obesity in elementary school-aged children. The author also found that there are many other causes that influence childhood obesity including genetic factors, environmental factors, and media.
Obesitas adalah penyakit yang menjadi masalah besar dibelahan dunia, penyakti ini menyerang kesegala umur bukan orang dewasa saja tetapi juga kepada usia anak dibawah umur. Penulisan artikel ini dilakukan karena tujuan penulis untuk mengetahui apakah terdapat hubungan antara aktivitas fisik dan pola makan terhadap obesitas peserta didik sekolah dasar. Metode: Penulis mengumpulkan artikel menggunakan database Google Scholar. Kata kunci yang digunakan aktivitas fisik terhadap obesitas, pola makan terhadap obesitas, dan effect physical activity on obesity, diet. Rentan tahun yaitu mulai dari tahun 2011 hingga tahun 2020. Artikel diatas menggunakan desain penelitian korelasional. Dari beberapa artikel yang direview sebagian sudah terindeks sinta S1-S6 atau scimago Q1-Q4. Hasil: Penulis menemukan 23 artikel dengan 20 artikel terbitan jurnal nasional dan 3 jurnal internasional. Hasil review yang dilakukan terhadap beberapa artikel diatas bahwa menunjukkan terhadap hubungan yang signifikan antara aktivitas fisik, pola makan dengan obesitas. Kesimpulan: Setelah melakukan proses review artikel penulis menemukan adanya hubungan antara aktivitas fisik dan pola makan terhadap obesitas anak usia sekolah dasar. Penulis juga menemukan bahwa banyak penyebab lain yang menjadi pengaruh obesitas anak diantaranya faktor genetik, faktor lingkungan dan media.
Overview of key educational platforms used for modern e-learning
Authors: Исаева В.С. 
Published: February 2022

Обзор основных образовательных платформ, использующихся для современного дистанционного обучения. Рассматриваются платформы, которые используются в процессе дистанционного обучения в Российском новом университете, а также их основные функции. Особое внимание уделено процессу получения образования с помощью программ Microsoft Teams и Moodle. Программу Microsoft Teams можно использовать для онлайн-встреч преподавателя со студентами и подробного разбора материала на лекциях, в то время как Moodle рассчитана на самостоятельное изучение учебных материалов (без помощи преподавателя) и прохождения тестирования для проверки знаний. Обе эти системы просты в использовании, и преподаватели легко могут применять их в учебном процессе.
The article discusses the platforms that are used in the process of distance learning in ANO VO «Ros-NOU», as well as their main functions. Particular attention is paid to the process of obtaining education using Microsoft Teams and Moodle programs. Microsoft Teams is well suited for online teacher-student meetings and detailed analysis of material in lectures, while Moodle is designed for self-study of educational materials (without the help of a teacher) and passing knowledge testing. Both of these systems are easy to use and teachers can easily use them in the educational process.
Method of choosing the structure of a specialized computer system of autonomous mobile objects that implement the preliminary processing of information
Authors: Басыров А.Г. , Кузнецов В.В. , Лупашко М.Н. 
Published: February 2022

Представлен подход к выбору структуры специализированной вычислительной системы, предназначенной для предварительной бортовой обработки целевой информации в автономных подвижных объектах. Предложен алгоритм расчета требуемого количества вычислительных модулей с учетом минимизации энерговременных затрат.
An approach to choosing the structure of a specialized computing system designed for preliminary onboard processing of target information in autonomous mobile objects is presented. An algorithm for calculating the required number of computing modules is proposed, taking into account the minimization of energy and time costs.