bluuebunny/crossref_metadata_2025_split huggingface dataset:
A balancing act–finding one´s way to health and well-being: A qualitative analysis of interviews with Swedish university students on lifestyle and behavior change
Authors: Åsberg Katarina , Eldh Ann Catrine , Löf Marie , Bendtsen Marcus 
Published: October 2022

Introduction
Unhealthy lifestyle behaviors such as unhealthy diets, low physical activity levels, smoking, and harmful alcohol consumption are common in student populations, which constitute a large group of young adults. As unhealthy lifestyle behaviors are associated with future disease and premature mortality, most commonly from cardiovascular disease and cancers, it is from a public health perspective important to understand such behaviors in young adult populations. The objective of this study was to investigate university students’ experiences of health, health-related behaviors, and the barriers and facilitators for behavior change in terms of health promotion in everyday life.

Materials and methods
This qualitative study was conducted at a middle-sized university in Sweden. Students represented different faculties and were recruited via non-probability convenience sampling using means such as the snowball technique and social media. The 21 interviews with 24 students, individually or in groups, were transcribed verbatim prior to a qualitative analysis inspired by phenomenological hermeneutics.

Results
Our interviews showed that university student life is associated with new health-related challenges, for example study-related stress and procrastination implies a lack of energy to engage in healthy routines such as physical activity, and a limited budget affects food choices. While adapting to a new context, students explore personal strategies such as taking on changes in manageable steps, seeking social support, and avoiding disturbances to maintaining health and quality of life.

Conclusions
Experiences of health while becoming and being a university student can be described as a transition–a balancing act of walking a slack line–during which students seek to manage a healthy balance. In the past, interventions have to some extent been designed to address university students’ behaviors; however, our study aids an understanding of their needs. Future interventions should highlight the transitions they are experiencing and the challenges of student life.
Role of fluid-phase complement system regulation in the development of hepatitis C virus-associated glomerulonephritis
Authors: Ibrahim Sara T. , Abdelhamid Marwa R. , Lewis Neveen , Baddour Nahed , Adam Ahmed G. 
Published: October 2022

Objectives
It is not known why only some hepatitis C virus (HCV) infected patients develop glomerulonephritis (GN). Therefore, we investigated the role of soluble complement regulators in the development of HCV associated GN.

Methods
Patients with HCV associated GN who were admitted to our nephrology unit between July 2016 and July 2018 were recruited to the study (group 1). Two other age and sex matched groups were studied as control groups: patients with HCV without GN (group 2) and healthy HCV negative volunteers (group 3). There were 26 participants in each of the three groups at the end of the recruitment period. An assay of serum fluid-phase complement regulators was performed using enzyme linked immunosorbent assay technique. Three complement single nucleotide polymorphisms (SNPs) were analyzed using real time polymerase chain reaction (Taqman; thermo fisher scientific): rs2230199 and rs1047286 for complement 3 (C3) and rs800292 for complement factor H (CFH).

Results
Serum levels of complement 4 binding protein (C4BP) were significantly lower in group 1 (median 70 ng/ml) than in groups 2 (median 88.8 ng/ml) and 3 (median 82.8 ng/ml) with p value of 0.007. The minor allele (allele A) of rs800292 for CFH was significantly higher in group 2 and group 3 (G 54% and A 46%) than in group 1 (G 73% and A 27%), p = 0.04.

Conclusions
Low C4BP levels are associated with GN in HCV infected patients. In addition, rs800292 SNP in CFH protects against GN in patients with HCV.
Scoop thrombectomy: A declotting technique for the treatment of thrombosed autologous arteriovenous fistula. A single-center retrospective study
Authors: Ruan Lin , Yang Yanli , Ren Guangwei , Li Wen , Sun Lijun , Zhang Lihong 
Published: October 2022

Background
Thrombosis is one of the main complications leading to the failure of autologous arteriovenous fistula (AVF) for patients with renal failure. Thrombectomy is one of the major therapies to remove thrombi to salvage the AVF and prolong its patency.

Materials and methods
Fifty-six patients with AVF thrombosis at the anastomosis were recruited for this study and underwent thrombectomy procedures. Their clinical variables were collected. The vasculature was accessed at the site of the aneurysmal dilatation. Under ultrasound guidance, a scoop thrombectomy procedure was performed by anterograde and retrograde scooping to remove the thrombus using forceps. Then, a sheath was placed in the direct vertical direction. Angioplasty was performed with a balloon to treat the underlying primary arteriovenous stenosis. Patients were followed up for 12 months after surgery. The procedural success, primary and secondary patency rates, and incidence of procedure-related complications were analyzed.

Results
There were 2 minor (3.6%) and no major complications. Clinical success was achieved in 55 of the 56 procedures (98.2%). No symptomatic pulmonary embolism or arterial embolization was noted. The primary patency rates at 3, 6, and 12 months were 92.9, 83.8, and 73.3%%, respectively, according to the Kaplan–Meier survival analysis.

Conclusion
Scoop thrombectomy is a safe procedure with high technical success and a low complication rate, and it is an effective method for patients to receive hemodialysis immediately.
Linaclotide Reduced Response Time for Irritable Bowel Syndrome With Constipation Symptoms: Analysis of 4 Randomized Controlled Trials
Authors: Brenner Darren M. , Lacy Brian E. , Ford Alexander C. , Bartolini Wilmin , Wu James , Shea Elizabeth P. , Bochenek Wieslaw , Boinpally Ramesh , Almansa Cristina 
Published: October 2022

INTRODUCTION:
These post hoc analyses provide clinically relevant data concerning time to response for individual irritable bowel syndrome with constipation (IBS-C) symptoms after linaclotide use.

METHODS:
Time-to-response data were pooled from 4 randomized controlled trials. Response time for abdominal symptoms (pain, discomfort, and bloating) and complete spontaneous bowel movements (CSBMs) were analyzed using the Kaplan-Meier method; patients were categorized as early responders (≤4 weeks), late responders (>4–12 weeks), or nonresponders.

RESULTS:
Among 2,350 patients (1,172 placebo and 1,178 linaclotide 290 μg), >50% of patients with IBS-C who initiated linaclotide treatment experienced a decrease of ≥30% in abdominal pain, discomfort, or bloating within 3–4 weeks (median). The median time to achieving ≥3 CSBMs was 4 weeks. Although not all linaclotide-treated patients responded within 12 weeks, a late response occurred between 4 and 12 weeks in 1 in 6 patients for abdominal pain and in approximately 1 in 10 patients for CSBM frequency. Comparisons of early responders, late responders, and nonresponders for both response definitions indicated that women, Whites, and patients with less severe baseline abdominal symptoms were more likely to respond early.

DISCUSSION:
Although treatment responses with linaclotide occurred in >50% of patients with IBS-C within 4 weeks of treatment initiation, benefits for individual abdominal symptoms and/or CSBM frequency can still occur between 4 and 12 weeks. A lack of improvement in one symptom does not negate the possibility of response for others, highlighting the importance of discussing all symptoms with patients and not assuming treatment futility at 4 weeks.
Changes in Lifestyle and Risk of Colorectal Cancer in the European Prospective Investigation Into Cancer and Nutrition
Authors: Botteri Edoardo , Peveri Giulia , Berstad Paula , Bagnardi Vincenzo , Chen Sairah L.F. , Sandanger Torkjel M. , Hoff Geir , Dahm Christina C. , Antoniussen Christian S. , Tjønneland Anne , Eriksen Anne Kirstine , Skeie Guri , Perez-Cornago Aurora , Huerta José María , Jakszyn Paula , Harlid Sophia , Sundström Björn , Barricarte Aurelio , Monninkhof Evelyn M. , Derksen Jeroen W.G. , Schulze Matthias B. , Bueno-de-Mesquita Bas , Sánchez Maria-Jose , Cross Amanda J. , Tsilidis Konstantinos K. , De Magistris Maria Santucci , Kaaks Rudolf , Katzke Verena , Rothwell Joseph A. , Laouali Nasser , Severi Gianluca , Amiano Pilar , Contiero Paolo , Sacerdote Carlotta , Goldberg Marcel , Touvier Mathilde , Freisling Heinz , Viallon Vivian , Weiderpass Elisabete , Riboli Elio , Gunter Marc J. , Jenab Mazda , Ferrari Pietro 
Published: October 2022

INTRODUCTION:
We investigated the impact of changes in lifestyle habits on colorectal cancer (CRC) risk in a multicountry European cohort.

METHODS:
We used baseline and follow-up questionnaire data from the European Prospective Investigation into Cancer cohort to assess changes in lifestyle habits and their associations with CRC development. We calculated a healthy lifestyle index (HLI) score based on smoking status, alcohol consumption, body mass index, and physical activity collected at the 2 time points. HLI ranged from 0 (most unfavorable) to 16 (most favorable). We estimated the association between HLI changes and CRC risk using Cox regression models and reported hazard ratios (HR) with 95% confidence intervals (CI).

RESULTS:
Among 295,865 participants, 2,799 CRC cases were observed over a median of 7.8 years. The median time between questionnaires was 5.7 years. Each unit increase in HLI from the baseline to the follow-up assessment was associated with a statistically significant 3% lower CRC risk. Among participants in the top tertile at baseline (HLI > 11), those in the bottom tertile at follow-up (HLI ≤ 9) had a higher CRC risk (HR 1.34; 95% CI 1.02–1.75) than those remaining in the top tertile. Among individuals in the bottom tertile at baseline, those in the top tertile at follow-up had a lower risk (HR 0.77; 95% CI 0.59–1.00) than those remaining in the bottom tertile.

DISCUSSION:
Improving adherence to a healthy lifestyle was inversely associated with CRC risk, while worsening adherence was positively associated with CRC risk. These results justify and support recommendations for healthy lifestyle changes and healthy lifestyle maintenance for CRC prevention.
Improved Right Ventricular Systolic Function After Cardiac Resynchronization Therapy in Patients With Heart Failure
Authors: Sadeghian Hakimeh , Kazemisaied Ali , Rezvanfard Mehrnaz , Jalali Arash , Sadeghian Afsaneh , Ashraf Haleh , Semnani Farbod , Raeini Amirhossein Ghaseminejad 
Published: October 2022

Background
Since the introduction of cardiac resynchronization therapy (CRT) to improve left ventricular function, the effect of CRT on the right ventricle in patients with heart failure has not been well described.

Methods
We evaluated the effect of CRT on right ventricular systolic function in 20 patients (80% men; mean [SD] age, 58.5 [9.8] y) with cardiomyopathy and right ventricular systolic dysfunction (New York Heart Association class III or IV, left ventricular ejection fraction ≤35%, and QRS interval ≥120 ms). The median follow-up time was 15 months. Right ventricular systolic function, defined as a tricuspid annular plane systolic excursion (TAPSE) index of 16 mm or less, was evaluated in patients before and after CRT.

Results
Twelve (60%) patients had ischemic cardiomyopathy, and 12 (60%) patients had left bundle branch block detected using surface electrocardiogram. The mean (SD) QRS duration was 160.5 (24.4) ms. From before CRT to the time of follow-up after CRT, the mean (SD) ejection fraction increased significantly from 22.5% (5.6%) to 29.4% (7.4%) (P < .001). The mean (SD) TAPSE index also increased significantly from 13.70 (1.78) mm to 16.50 (4.77) mm (P = .018). Eleven (55%) patients showed improved right ventricular systolic function (TAPSE ≥16 mm) after CRT. Patients with a favorable right ventricular response to CRT were significantly older (64.6 [8.2] y vs 53.6 [8.4] y, respectively) and more likely to have nonischemic origin of cardiomyopathy than were patients with unimproved right ventricular function (66.7% vs 18.2%, respectively).

Conclusion
Our findings indicate that CRT is associated with improved right ventricular systolic function in patients with heart failure and right ventricular systolic dysfunction. Patients with nonischemic heart disease more often show improved right ventricular function after CRT.
Zur Idee der Freiheit
Authors: Stemmer Peter 
Published: October 2022

AbstractEuropean culture is distinguished by a special and indeed unique appreciation of freedom. Understanding why we care so much about freedom requires continual reflection on the heart of the matter. This is especially necessary because the concept of freedom has been constantly reworked and remodelled throughout its long history. This article lists five key characteristics and highlights two in particular: (1) the openness of being free, which means that freedom does not itself determine what it is used for; and (2) the fact that freedom is by its nature an extrinsic, not an intrinsic, end. In addition, the article comments on various highly influential aberrations in the explication of the idea of freedom that began early, in the 4th century, with Plato.
Konkrete Geschichtlichkeit?
Authors: Romero José M. 
Published: October 2022

Abstract
This article reconstructs Herbert Marcuse’s first and widely ignored philosophical project, as set out in his texts published from 1928 to 1933. In these texts, Marcuse tried to put in dialogue ideas from Heidegger and Marx to articulate a dialectic phenomenology of historical existence. This attempt, of great originality and philosophical ambition, was marked by tensions arising from the peculiar status given to the ontology of historicity in a framework of thought that maintained strong links with Marx. By analysing this early philosophical project of one of the icons of the international student movement, theoretical tensions can be detected, which clarify the subsequent approach of this thinker as a member of the so-called Frankfurt School.
„Gerstenberg ist unser gröste Poet vielleicht…“
Authors: Paulsen Adam 
Published: October 2022

AbstractAlthough they never met and exchanged only one letter during their lifetime, Danish-German poet and literary critic Heinrich Wilhelm Gerstenberg and German theologian, philosopher and literary critic Johann Gottfried Herder took great interest in each other’s work. Indeed, during the late 1760s Gerstenberg’s writings on literature, history and translation arguably had an immense impact on Herder, providing him with some of the major themes and insights for the Sturm und Drang movement, that took place in Germany around 1770 with Herder in a leading role. On the basis of Herder’s writings and letters from the 1760s throughout his life, this article examines for the first time to what extent Gerstenberg informed Herder’s views on ancient Nordic literature, Shakespeare, Ossian and the concept of genius.
Naturens Amfiteater. Kunstens natur
Authors: Klitgaard Povlsen Karen 
Published: October 2022

Abstract
Friederike Brun, née: Münter (1765–1835) became a famous writer in the German-speaking areas of Europe around 1800. She published collections of poems and travelogues in German, brought up as she was in the German and cosmopolitan circle in Copenhagen around Klopstock, Gerstenberg, her father, court chaplain Balthasar Münter, and others. Not least the writings of Ossian (MacPherson), Shakespeare, Gray and Richardson influenced her together with J. J. Rousseau. This contribution focuses on her early writings from 1782 until 1790. They have so far been neglected in research, being the products of a young woman, but they show the wide horizon of her circle, her father’s education of her, his introduction of her to the German intellectual elite of the time and her talent as a writer in a sentimental and enlightened-romantic tradition inspired by Schiller and Herder. She is interested in the aesthetics of nature and the relations between nature and culture and can in this respect be seen as an early ecocritical writer. Furthermore, she demonstrates female emancipation around 1800 and a cosmopolitical consciousness in a Europe heading towards national boundaries as well as language and gender barriers.
Auswirkungen der Corona-Pandemie auf das freiwillige Engagement älterer Menschen in der Schweiz
Authors: Kirchschlager Stephan , Störkle Mario 
Published: October 2022

ZusammenfassungDer Beitrag stellt die Ergebnisse einer Studie aus der Schweiz ins Zentrum, die sich mit den Auswirkungen der Corona-Pandemie auf das Engagement von Menschen im höheren Lebensalter sowie auf deren persönliche Lebenssituation als Zugehörige einer Risikogruppe beschäftigt. Die Studie zeigt, wie die Befragten ihr Leben auch während der Pandemie aktiv gestalten und Wege finden, ihr Engagement fortzuführen. Bei den Befragten ambivalent bleibt insbesondere der Aspekt, sich einerseits fit, gesund und aktiv zu fühlen und andererseits pauschal zur vulnerablen Gruppe zu gehören.
Financial Instability and International-Lender-of-Last-Resort Theory from the Gold Standard to the Dollar System
Authors: Carré Emmanuel , Le Maux Laurent 
Published: October 2022

Abstract
We identify two approaches to financial crises in the history of political economy, namely, the exogenous approach whereby financial crises are sudden events, and the endogenous approach whereby they arise from a long process. In focusing on the endogenous approach, we study the contributions by Thomas Tooke, Ralph Hawtrey, Hyman Minsky and Charles Kindleberger to the lender-of-last-resort theory, especially in international contexts, under the gold standard and the dollar system. The function of the lender of last resort broadens institutionally (depending on the type of securities and on the institutions issuing or holding them) and internationally (depending on jurisdiction and on the type of institutions ultimately requiring international liquidity).
Strategi Kepemimpinan Kepala Sekolah Terhadap Kinerja Guru Dalam Meningkatkan Mutu Di Sekolah Dasar
Authors: Syifauzzuhrah Nabillah 
Published: October 2022

Kepemimpinan kepala sekolah sangat berpengaruh bahkan sangat menentukan terhadap kemajuan sekolah. Untuk meningkatkan mutu pendidikan maka kepala sekolah menerapkan prinsip-prinsip kepemimpinan dan prinsip-prinsip pengelolaan kualitas total yang mendukung peningkatan mutu. Kepemimpinan kepala sekolah dalam mencapai mutu pendidikan yang diharapkan bukanlah merupakan hasil dan ditentukan oleh karya perseorangan, namun justru merupakan karya dari team work yang cerdas. Untuk itu, kepala sekolah dituntut memiliki kemampuan manajerial yang baik serta mampu mendorong seluruh bawahan untuk dapat memberdayakan dirinya. Penelitian ini bertujan untuk mendeskripsikan strategi kepala sekolah terhadap kinerja guru dalm meningkatkan mutu pendidikan khususnya di sekolah dasar. Jenis penelitian ini adalah kualitatif serta kajian pustaka. Hasilnya yaitu ada beberapa strategi yang harus dilakukan kepala sekolah terkait dengan peningkatan mutu yaitu 1) menyusun perencanaan dan pengembangan sekolah dengan merumuskan visi, misi, dan tujuan jangka pendek. 2) pelaksanaan strategi dengan meningkatkan kedisiplinan 3) meningkatkan hasil ujian di setiap tahunnya 4) senantiasa menjalin komunikasi dan kerjasama yang baik dengan komite, wali murid, alumni dan lembaga-lembaga pemerintah terdekat 5) evaluasi pelaksanaan program.
New record of Tylodelphys metacercariae (Diplostomidae) from Perccottus glenii (Odontobutidae) and their phylogenetic assessment
Authors: Sokolov Sergey G. , Yang Peimin , Lebedeva Daria I. 
Published: October 2022

AbstractMetacercariae of Tylodelphys sp. were found in the abdominal cavity of the Chinese sleeper (Perccottus glenii) collected in Liaoning Province and Inner Mongolia Autonomous Region of China. The sequences of the mitochondrial cox1 gene and ribosomal ITS1–5.8S rDNA–ITS2 region were obtained and used for molecular identification and phylogenetic assessment of this parasite species. Results of phylogenetic analyses based on ITS and cox1 markers showed that the metacercariae of Tylodelphys sp. ex P. glenii from China were conspecific with specimens of Tylodelphys sp. collected by Sokolov et al. (2013) from the same fish-host species captured earlier in West Siberia, Russia. The examined Tylodelphys sp. ex. P. glenii is the only member of the genus whose metacercariae parasitise the abdominal cavity of fish in northern Eurasia. Tylodelphys sp. ex P. glenii clustered with T. darbyi, T. immer, T. podicipina, and Tylodelphys sp. of Soldánová et al., 2017 based on mitochondrial DNA markers, and with T. darbyi, T. immer, T. kuerepus, and T. schreuringi using nuclear DNA markers.
Quality evaluation of Codonopsis Radix through high performance liquid chromatography fingerprint combined with chemometrics and simultaneous determination of five characteristic ingredients
Authors: An Qi , Sun Hong , Wu Linzhi , Liu Liangliang , Chen Sue 
Published: October 2022

AbstractCodonopsis Radix (CR) is recorded as the roots of Codonopsis pilosula, C. pilosula var. modesta and Codonopsis tangshen. It is difficult to evaluate the quality of CR because of the existence of many original plants. In this paper, a strategy integrating chromatographic analysis and chemometrics for the quality control of CR is proposed. Systematic analysis of the chemical composition of CR was achieved through high performance liquid chromatography (HPLC) fingerprinting. Based on the HPLC fingerprinting data, chemometrics, including unsupervised principal component analysis (PCA) and supervised orthogonal partial least squares-discrimination analysis (OPLS-DA), were applied to classify all CR samples. Components with variable importance in projection values higher than 1 in the OPLS-DA model were selected as potential chemical markers for distinguishing the origins of CR. Finally, an HPLC method was validated for determining the five characteristic ingredients in the CR samples. HPLC characteristic fingerprints showed 17 common peaks for C. pilosula, 13 for C. pilosula var. modesta, and 9 for C. tangshen, and all of them showed good similarity (>0.9). Additionally, there were 9 common peaks for all CR samples with relatively poor similarity, ranging from 0.607 to 0.970. PCA could differentiate CR from the three origins, except for a partial overlap between C. pilosula and C. pilosula var. Modesta, and the OPLS-DA model achieved excellent classification results. Eight components (peaks 12, 8, lobetyolin, 10, codonopsin І, syringin, 3, and 11) were selected as potential chemical markers. There was a large discrepancy in the contents of the five characteristic ingredients in all samples, with the relative standard deviation ranging from 36.0% (lobetyolin) to 85.9% (atractylenolide Ⅲ). The average contents of the five characteristic ingredients were similar between C. pilosula and C. pilosula var. modesta samples and notably higher than those of C. tangshen samples. Consequently, a rapid, precise, and feasible strategy was established for the discrimination and quality control of CR with different origins.