bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validation of a body condition scoring system in Nili Ravi dairy buffaloes (Bubalus bubalis): inter- and intra-assessor variability
Authors: Magsi Sayyad H. , Ahmad Nisar , Rashid Muhammad A. , Bah Musa , Akhter Maqsood , Shahid Muhammad Q. 
Published: November 2022

AbstractThe aim of the research reported in this Research Communication was to apply the 5-point body condition scoring (BCS) system to dairy buffaloes and subjectively validate it by assessing the intra- and inter-assessor agreement. For this purpose, the BCS system developed for dairy cows was applied to buffaloes. A total of 230 Nili Ravi buffaloes of varying parity, lactation stages and pregnancy status were enrolled from the Buffalo Research Institute, Pattoki, Pakistan. Four observers independently assigned BCS values to each enrolled buffalo in two phases, as follows: (1) during phase I, the assessors were trained for BCS assessment using a BCS chart developed by Elanco Animal Health Ltd.; and (2) during phase II, the assessors were trained using live buffaloes for BCS assessment. Kappa statistics (kw) were used to determine the intra- and inter-assessor agreement. The results revealed that the exact overall inter- and intra-assessor agreement was moderate (kw = 0.48–0.55) and increased to substantial levels after training on live animals (kw = 0.63–0.87). Furthermore, the intra- and inter-assessor exact agreement was higher (kw = 0.57–0.58) for buffaloes tied to the mangers compared to the buffaloes standing in the loafing area (kw = 0.50). The inter-assessor agreements within 0.25 and 0.5 points were almost perfect (kw = 0.97–1.0). The current results suggested that the 5-point BCS system (using a scale from 1 to 5 with 0.25 increments) had substantial agreement for assessment and repeatability when applied to buffaloes.
Recruitment of the endangered limpet Patella ferruginea in the Chafarinas Islands (SW Mediterranean)
Authors: Guallart Javier , Templado José , Luque Ángel A. 
Published: November 2022

AbstractThe recruitment of the endangered limpet Patella ferruginea in the Chafarinas Islands (SW Mediterranean) was studied over a 17-year period (1999‒2015). A total of 8115 recruits <20 mm in maximum diameter were counted in 95 transect censuses sampled during the study period. The presence of recruits began at the end of winter or beginning of spring (March‒April), when they reached a maximum shell diameter (MD) of at least 4 mm, with a peak in abundance occurring in spring. Smaller recruits were found on the lower midlittoral on the fringe of the vermetid gastropod Dendropoma lebeche and the crustose coralline algae Neogoniolithon brassica-florida, which suggests that settlement occurs at this shore level. Recruits reach 12‒27 mm at the end of their first year of life. A regular recruitment was detected for all studied years, with an average of 11.71 recruits m−1 across the study period. However, recruitment exhibited high interannual variability and did not occur evenly along the coastline of the islands. Higher recruitment was observed in 2001, 2011 and 2012, with a maximum density of 69.07 recruits m−1 in one transect in 2012. The density of recruits decreased in summer. No significant correlation was found between the density of recruits and adults. Between 1999‒2010, 29.29% of recruits were ‘phoretic’ on the shell of adults (1.81 recruits per host on average). Recruits climbed on to adults sometime after settlement, thus we suggest that ‘phoresy’ could favour the survival of young limpets instead of being due to selective settlement on adults. To improve and standardize recruitment monitoring in future studies, we propose that recruits are considered as those specimens <20 mm in MD and that recruitment censuses are carried out in spring, with additional censuses after summer to detect juvenile mortality. Additionally, we propose that 1 mm interval size classes are used for growth studies based on size‒frequency analyses.
Which patients benefit from adding short-term psychodynamic psychotherapy to antidepressants in the treatment of depression? A systematic review and meta-analysis of individual participant data
Authors: Driessen Ellen , Fokkema Marjolein , Dekker Jack J. M. , Peen Jaap , Van Henricus L. , Maina Giuseppe , Rosso Gianluca , Rigardetto Sylvia , Cuniberti Francesco , Vitriol Veronica G. , Andreoli Antonio , Burnand Yvonne , López Rodríguez Jaime , Villamil Salcedo Valerio , Twisk Jos W. R. , Wienicke Frederik J. , Cuijpers Pim 
Published: November 2022

AbstractBackgroundAdding short-term psychodynamic psychotherapy (STPP) to antidepressants increases treatment efficacy, but it is unclear which patients benefit specifically. This study examined efficacy moderators of combined treatment (STPP + antidepressants) v. antidepressants for adults with depression.MethodsFor this systematic review and meta-analysis (PROSPERO registration number: CRD42017056029), we searched PubMed, PsycINFO, Embase.com, and the Cochrane Library from inception to 1 January 2022. We included randomized clinical trials comparing combined treatment (antidepressants + individual outpatient STPP) v. antidepressants in the acute-phase treatment of depression in adults. Individual participant data were requested and analyzed combinedly using mixed-effects models (adding Cochrane risk of bias items as covariates) and an exploratory machine learning technique. The primary outcome was post-treatment depression symptom level.ResultsData were obtained for all seven trials identified (100%, n = 482, combined: n = 238, antidepressants: n = 244). Adding STPP to antidepressants was more efficacious for patients with high rather than low baseline depression levels [B = −0.49, 95% confidence interval (CI) −0.61 to −0.37, p < 0.0001] and for patients with a depressive episode duration of >2 years rather than <1 year (B = −0.68, 95% CI −1.31 to −0.05, p = 0.03) and than 1–2 years (B = −0.86, 95% CI −1.66 to −0.06, p = 0.04). Heterogeneity was low. Effects were replicated in analyses controlling for risk of bias.ConclusionsTo our knowledge, this is the first study that examines moderators across trials assessing the addition of STPP to antidepressants. These findings need validation but suggest that depression severity and episode duration are factors to consider when adding STPP to antidepressants and might contribute to personalizing treatment selection for depression.
Slave Resistance in Early Medieval England
Authors: Fontaine Janel M. 
Published: November 2022

ABSTRACTConsidering early medieval slave resistance proves difficult, given our limited knowledge of all people of low status, especially slaves. Without oral histories, slave narratives, or strong indications of agency, we cannot confidently move beyond discussion of what slave-owners feared into what slaves intended. In lieu of broad discussion of slave agency for early medieval England, we can speak instead of the anticipated problems of slave-ownership. Elites were most concerned by behaviours which could fall into three overlapping categories of ‘problems’: those of property ownership, labour and violence. Each issue focusses heavily on legal responsibility for actions by slaves within a communal compensation-based legal system. Examination of these fears indicates that lawmakers and slave-owning elites were consistently engaged in problematizing slave-ownership, either in reaction to known slave behaviour or in anticipation of it. What emerges, then, is a situation in which both real and imagined acts of resistance helped shape ideas of power and authority both at a personal and administrative level. The expectations of slave behaviour also illuminate some aspects of slavery’s role in society.
Sleep Problems and Psychological Well-Being: Baseline Findings from the Canadian Longitudinal Study on Aging
Authors: Rodrigues Rebecca , Nicholson Kathryn , Guaiana Giuseppe , Wilk Piotr , Stranges Saverio , Anderson Kelly K. 
Published: November 2022

AbstractInternational studies have demonstrated associations between sleep problems and poor psychological well-being; however, Canadian data are limited. This study investigated this association using cross-sectional baseline data from the Canadian Longitudinal Study on Aging, a national survey of 30,097 community-dwelling adults, 45–85 years of age. Short sleep duration, sleep dissatisfaction, insomnia symptoms, and daytime impairment were consistently associated with a higher prevalence of dissatisfaction with life, psychological distress, and poor self-reported mental health. Long sleep duration was associated with a higher prevalence of psychological distress and poor self-reported mental health, but not with dissatisfaction with life. Associations between sleep problems and psychological distress were 11–18 per cent stronger in males. With each 10-year increase in age, the association between daytime impairment and life dissatisfaction increased by 11 per cent, and insomnia symptoms and poor mental health decreased by 11 per cent. Sleep problems in middle-aged and older adults warrant increased attention as a public health problem in Canada.
A dilemma of World Heritage ideals and challenges in Southeast Asia
Authors: Miura Keiko 
Published: November 2022

AbstractFifty years after the ratification of the World Heritage Convention, we have come to learn that there is a huge discrepancy between the United Nations Educational, Scientific and Cultural Organization’s (UNESCO) ideals of protecting heritage sites with outstanding universal values and unmatched realities in situ. I attempt to elucidate what World Heritage ideals of heritage protection are held in iconic sites in Southeast Asia. The studied sites are ancient monumental heritage sites of national importance – namely, Borobudur of Indonesia, Sukhothai and Ayutthaya of Thailand, and Angkor of Cambodia. The authorities in these countries have converted heritage sites into parks for visitors and for capitalization, which has placed authenticity and integrity at stake as well as converting the sites for contestation between the authorities and local communities. In order to solve the dilemma of the World Heritage ideals and their unwanted realities, I explore possible effective approaches for UNESCO and its partners to take into consideration.
Factors affecting incidental L2 vocabulary acquisition and retention in a game-enhanced learning environment
Authors: Lee Sangmin-Michelle 
Published: November 2022

AbstractIn recent years, the number of studies investigating the effectiveness of using digital games for incidental second language (L2) vocabulary learning has been rapidly increasing; however, there is still a lack of research identifying the factors that affect incidental L2 vocabulary learning. Hence, the current study examined vocabulary-related (word level, exposure frequency, salience) and learner-related (language proficiency, interest, viewing captions) variables and investigated factors affecting EFL students’ incidental vocabulary learning in the use of a vernacular (noneducational) murder mystery game (N = 59). The study employed a quantitative research method and descriptive and inferential statistics (repeated measures ANOVA and multiple linear regression). The results showed that playing the game greatly facilitated L2 vocabulary acquisition and retention. Among the vocabulary-related variables, the study found that only salience significantly influenced vocabulary acquisition. Regarding the learner-related variables, the students’ interest and viewing captions were positively related to vocabulary learning, whereas their language proficiency levels were negatively correlated. The study found that the students’ conscious attention, in conjunction with salience of the word, was the main facilitating factor in incidental vocabulary acquisition and retention in the game-enhanced language learning environment. The study suggested pedagogical implications for incidental vocabulary learning through game play based on the results of the study.
A novel algorithm for classification of interatrial communications within the oval fossa in the newborn
Authors: Dannesbo Sofie , Blixenkrone-Moeller Elisabeth , Pihl Christian A. , Sillesen Anne-Sophie , Voegg Ruth O. , Davidsen Agnes S. , Lind Louise E. , Jeppesen Dorthe L. , Kruse Charlotte , Noerager Betina , Dodd James K. , Jorgensen Finn S. , Raja Anna A. , Colan Steven D. , Mertens Luc , Hjortdal Vibeke E. , Vejlstrup Niels , Anderson Robert H. , Bundgaard Henning , Iversen Kasper 
Published: November 2022

AbstractBackground:An interatrial communication is present in most neonates. The majority are considered the “normal” patency of the oval foramen, while a minority are abnormal atrial septal defects. Differentiation between the two with transthoracic echocardiography may be challenging, and no generally accepted method of classification is presently available. We aimed to develop and determine the reliability of a new classification of interatrial communications in newborns.Methods and Results:An algorithm was developed based on echocardiographic criteria from 495 newborns (median age 11[8;13] days, 51.5% females). The algorithm defines three main categories: patency of the oval foramen, atrial septal defect, and no interatrial communication as well as several subtypes. We found an interatrial communication in 414 (83.6%) newborns. Of these, 386 (93.2%) were categorised as patency of the oval foramen and 28 (6.8%) as atrial septal defects.Echocardiograms from another 50 newborns (median age 11[8;13] days, 36.0% female), reviewed by eight experts in paediatric echocardiography, were used to assess the inter- and intraobserver variation of classification of interatrial communications into patency of the oval foramen and atrial septal defect, with and without the use of the algorithm. Review with the algorithm gave a substantial interobserver agreement (kappa = 0.66), and an almost perfect intraobserver agreement (kappa = 0.82). Without the use of the algorithm, the interobserver agreement between experienced paediatric cardiologists was low (kappa = 0.20).Conclusion:A new algorithm for echocardiographic classification of interatrial communications in newborns produced almost perfect intraobserver and substantial interobserver agreement. The algorithm may prove useful in both research and clinical practice.
Genetic characterization of oleaginous bottle gourd (Lagenaria siceraria) germplasm from Côte d'Ivoire using agromorphological and molecular markers
Authors: Gbotto Ahou Anique , Yao Nasser Kouadio , Kitavi Mercy , Osama Sarah Karen , Habimana Richard , Koffi Kouamé Kevin , Zoro Bi Irié Arsène 
Published: November 2022

AbstractBeing difficult to regenerate and maintain the seeds, the oleaginous bottle gourd was investigated using nine agromorphological traits and 31 amplified fragment length polymorphism (AFLP) markers. Specifically, the study was conducted to determine the intra-specific variability of a total of 173 accessions, which were identified from five agro-ecological regions from Côte d'Ivoire (Centre, East, North and South). Then, the genetic diversity and relationships within accessions were studied using AFLP markers. This characterization using both morphological and AFLP markers was realized in order to ultimately build a reliable core collection. The discriminant analysis, using nine quantitative traits, reveals plant length and seeds number per fruit as discriminating characteristics. From the accessions used for the agromorphological study, 148 were able to be differentiated by the AFLP markers. A range of 52 to 113 bands were amplified per primer combination. As revealed by the analysis of molecular variance (AMOVA), 28% of the total variation resides among accessions and 72% occurs within populations. The AMOVA computed in order to differentiate cultivars, displayed the same trends when no prior grouping of accessions was considered. The differentiation within cultivar (97%) was more than that, among cultivars (3%). Tree topologies inferred by neighbour-joining analysis reflected no clear cut off grouping.To group accessions, we used a Bayesian clustering analysis which exhibited two clusters. Using the informativeness of the primer combinations analysed in the present study, an orientation was given for the choice of the accessions which would be used to build a core collection.
Taking economic and social rights earnestly: What does international human rights law offer persons with disabilities in situations of armed conflict?
Authors: de Beco Gauthier 
Published: November 2022

AbstractThis article studies the economic and social rights of people with disabilities in times of armed conflict. While hostilities prevent them from accessing the essential goods and services that they rely on to enjoy these rights, the topic has attracted little attention to date. Calling upon international human rights law, the article applies the Convention on the Rights of Persons with Disabilities, with a view to complementing the provisions of international humanitarian law. It focuses on the requirements above the provision of medical care and examines the legal obligations attached to economic and social rights.
Conference Committee Structure and Majority Party Bias in U.S. States
Authors: Emrich Colin 
Published: November 2022

AbstractHow representative are conference delegations in state legislative chambers? I argue that differing conference rules across state legislative chambers influence majority party control over conference delegations. With an original data set encompassing all state-level conference committees from 2005 to 2016, I compare the observed policy preferences between conference delegation and majority party medians when the majority party unilaterally appoints and when the minority party has influence over conferee selection. My results show that in state legislative chambers where the minority can influence conference appointments, delegations are ideologically biased away from the majority party. These findings underscore how majority parties are limited when minorities have procedural rights.
Divergent Electoral Policies: Why Some States Increase Ballot Access
Authors: Smith Kelly B. , Hill David , Ancheva Slavina 
Published: November 2022

AbstractWhy have some states adopted policies expanding ballot access while others have restricted access to the ballot? Since the 1990s, some states have been adopting policies restricting access to the ballot such as requiring identification. At the same time, states have been adopting a variety of registration reforms that lower the barriers to registration and voting. Using an original, 45-state dataset, we examine state innovation within the policy domain of electoral reforms in US states. We find reforms have an independent and, sometimes, negative effect on the innovation of states in electoral reforms. Next, we use dyad analysis to examine the spread of a single policy: automatic voter registration. We find that the propensity to innovate both within and across a state makes the spread of automatic voter registration more likely. Our paper contributes to the broader understanding of why states adopt electoral reforms.
A genetically informed prediction model for suicidal and aggressive behaviour in teens
Authors: Tate Ashley E. , Akingbuwa Wonuola A. , Karlsson Robert , Hottenga Jouke-Jan , Pool René , Boman Magnus , Larsson Henrik , Lundström Sebastian , Lichtenstein Paul , Middeldorp Christel M. , Bartels Meike , Kuja-Halkola Ralf 
Published: November 2022

AbstractSuicidal and aggressive behaviours cause significant personal and societal burden. As risk factors associated with these behaviours frequently overlap, combined approaches in predicting the behaviours may be useful in identifying those at risk for either. The current study aimed to create a model that predicted if individuals will exhibit suicidal behaviour, aggressive behaviour, both, or neither in late adolescence. A sample of 5,974 twins from the Child and Adolescent Twin Study in Sweden (CATSS) was broken down into a training (80%), tune (10%) and test (10%) set. The Netherlands Twin Register (NTR; N = 2702) was used for external validation. Our longitudinal data featured genetic, environmental, and psychosocial predictors derived from parental and self-report data. A stacked ensemble model was created which contained a gradient boosted machine, random forest, elastic net, and neural network. Model performance was transferable between CATSS and NTR (macro area under the receiver operating characteristic curve (AUC) [95% CI] AUCCATSS(test set) = 0.709 (0.671–0.747); AUCNTR = 0.685 (0.656–0.715), suggesting model generalisability across Northern Europe. The notable exception is suicidal behaviours in the NTR, which was no better than chance. The 25 highest scoring variable importance scores for the gradient boosted machines and random forest models included self-reported psychiatric symptoms in mid-adolescence, sex, and polygenic scores for psychiatric traits. The model’s performance is comparable to current prediction models that use clinical interviews and is not yet suitable for clinical use. Moreover, genetic variables may have a role to play in predictive models of adolescent psychopathology.
An effective and chemotherapy-free strategy of all-trans retinoic acid and arsenic trioxide for acute promyelocytic leukemia in all risk groups (APL15 trial)
Authors: Wang Huai-Yu , Gong Sha , Li Guo-Hui , Yao Ya-Zhou , Zheng Yin-Suo , Lu Xiao-Hong , Wei Su-Hua , Qin Wei-Wei , Liu Hai-Bo , Wang Meng-Chang , Xi Jie-Ying , Chen Li-Mei , Zhang Mei , Zhang Xin-Xin , Zhang Hui-Yun , Zhang Cheng-Sheng , Wald David N. , Zhu Hong-Hu , Liu Li , He Peng-Cheng 
Published: November 2022

AbstractThe combination of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) has been demonstrated to have comparable effectiveness or better to ATRA and chemotherapy (CHT) in non-high-risk acute promyelocytic leukemia (APL). However, the efficacy of ATRA-ATO compared to ATRA-ATO plus CHT in high-risk APL remains unknown. Here we performed a randomized multi-center non-inferiority phase III study to compare the efficacy of ATRA-ATO and ATRA-ATO plus CHT in newly diagnosed all-risk APL to address this question. Patients were assigned to receive ATRA-ATO for induction, consolidation, and maintenance or ATRA-ATO plus CHT for induction followed by three cycles of consolidation therapy, and maintenance therapy with ATRA-ATO. In the non-CHT group, hydroxyurea was used to control leukocytosis. A total of 128 patients were treated. The complete remission rate was 97% in both groups. The 2-year disease-free, event-free survival rates in the non-CHT group and CHT group in all-risk patients were 98% vs 97%, and 95% vs 92%, respectively (P = 0.62 and P = 0.39, respectively). And they were 94% vs 87%, and 85% vs 78% in the high-risk patients (P = 0.52 and P = 0.44, respectively). This study demonstrated that ATRA-ATO had the same efficacy as the ATRA-ATO plus CHT in the treatment of patients with all-risk APL.