bluuebunny/crossref_metadata_2025_split huggingface dataset:
What happens to your body during learning with computer-based environments? Exploring negative academic emotions using psychophysiological measurements
Authors: Huber Kerstin , Bannert Maria 
Published: March 2022

AbstractThis explorative study aims to examine if electrodermal activity (EDA) and heart rate (HR) are appropriate measures for identifying and monitoring academic emotions during learning in computer-based learning environments (CBLEs). Understanding learners' emotions while using CBLEs, allows improving the design of CBLEs. Therefore, we collected EDA, HR, and self-report data from 32 participants to measure academic emotions during learning with CBLEs in a laboratory setting. We induced negative academic emotions during learning using harmful connotated learning content about animal welfare. In a pre-post design, participants reported their emotional state before and after learning. We collated the self-reports with the EDA and HR curves to identify the emotional change in real-time. We prepared the data for repeated measurement analyses and group differences (high-, middle-, low learning performance; bored vs. not bored participants). Negative academic emotions were detected in increased EDA and HR. EDA turned out to be an indicator of learning performance. Boredom manifested in HR decrease. Findings show that EDA and HR are appropriate tools to measure academic emotions. We want to show the importance of real-time measures for learning and the efficiency of EDA and HR measures. It is worth considering EDA as a predictor for learning success and implementing EDA and HR measurements in CBLEs. However, more research is needed to clarify the role of HR in the context of learning performance.
The hidden dimensions of a change from below: Consequence markers in Montreal French
Authors: Blondeau Hélène , Tremblay Mireille 
Published: March 2022

AbstractThis article examines the rise of vernacular consequence marker ça-fait-que (CFQ), often realized as [fɛk] or [fak], at the expense of its standard counterparts donc and alors in Montreal French. The apparent-time analysis is based on a 2012 corpus of semi-directed interviews collected in Montreal. Previous studies treated the CFQ/donc/alors alternation as a purely lexical sociolinguistic variable. Our analysis shows how a vernacular variant (CFQ), initially associated with the working class and stigmatized, comes to compete, develop as a default form, and eventually crowd out forms at the other end of the social prestige scale (alors and donc). We rely on new socio-phonetic considerations to unveil a reconfiguration of the variable. The integration of the sociophonetic dimension sheds light on a complex process of diffusion, where a change from below is propelled by an additional change, but from above. Our article shows the key role played by women in both changes.
Sustainment of a complex culturally competent care intervention for Hispanic living donor kidney transplantation: A longitudinal analysis of adaptations
Authors: Gordon Elisa J. , Uriarte Jefferson J. , Anderson Naomi , Smith Justin Dean , Caicedo Juan Carlos , Shumate Michelle 
Published: March 2022

AbstractIntroduction:Sustainment refers to continued intervention delivery over time, while continuing to produce intended outcomes, often with ongoing adaptations, which are purposeful changes to the design or delivery of an intervention to improve its fit or effectiveness. The Hispanic Kidney Transplant Program (HKTP), a complex, culturally competent intervention, was implemented in two transplant programs to reduce disparities in Hispanic/Latinx living donor kidney transplant rates. This study longitudinally examined the influence of adaptations on HKTP sustainment.Methods:Qualitative interviews, learning collaborative calls, and telephone meetings with physicians, administrators, and staff (n = 55) were conducted over three years of implementation to identify HKTP adaptations. The Framework for Reporting Adaptations and Modifications-Expanded was used to classify adaptation types and frequency, which were compared across sites over time.Results:Across sites, more adaptations were made in the first year (n = 47), then fell and plateaued in the two remaining years (n = 35). Adaptations at Site-A were consistent across years (2017: n = 18, 2018: n = 17, 2019: n = 14), while Site-B made considerably fewer adaptations after the first year (2017: n = 29, 2018: n = 18, 2019: n = 21). Both sites proportionally made mostly skipping (32%), adding (20%), tweaking (20%), and substituting (16%) adaptation types. Skipping- and substituting-type adaptations were made due to institutional structural characteristics and lack of available resources, respectively. However, Site-A’s greater proportion of skipping-type adaptations was attributed to greater system complexity, and Site-B’s greater proportion of adding-type adaptation was attributed to the egalitarian team-based culture.Conclusion:Our findings can help prepare implementers to expect certain context-specific adaptations and preemptively avoid those that hinder sustainment.
Further properties of fractional stochastic dominance
Authors: Mao Tiantian , Wu Qinyu , Hu Taizhong 
Published: March 2022

AbstractA continuum of stochastic dominance rules, also referred to as fractional stochastic dominance (SD), was introduced by Müller, Scarsini, Tsetlin, and Winkler (2017) to cover preferences from first- to second-order SD. Fractional SD can be used to explain many individual behaviors in economics. In this paper we introduce the concept of fractional pure SD, a special case of fractional SD. We investigate further properties of fractional SD, for example the generating processes of fractional pure SD via
$\gamma$
-transfers of probability, Yaari’s dual characterization by utilizing the special class of distortion functions, the separation theorem in terms of first-order SD and fractional pure SD, Strassen’s representation, and bivariate characterization. We also establish several closure properties of fractional SD under quantile truncation, under comonotonic sums, and under distortion, as well as its equivalence characterization. Examples of distributions ordered in the sense of fractional SD are provided.
Story order in attribution of moral responsibility
Authors: Limata Teresa , Ianì Francesco , Bucciarelli Monica 
Published: March 2022

AbstractDiscourse comprehension relies on the construction of a mental model that represents the unfolding in time of the events described. In causal scenarios, where the action of one agent (the enabler) temporally precedes and enables the action of another agent (the causer), discourse may reflect the underlying event structure by describing the enabler’s action first and then the causer’s action (story order) or may describe the causer’s action first (backward order). Studies in the literature have shown that adults consider causers to be more responsible than enablers in moral scenarios. Based on the assumption that story order favors the construction of a mental model of events, we conducted an experiment to test the prediction that preference for the causer over the enabler should be greater when events are presented in story order than in backward order. The participants in the experiment were 42 fifth-grade children, 42 adolescents, and 42 adults. The results of the experiment confirmed the prediction for all three groups of participants. We discuss the practical implications of these results for learning contexts, legal contexts, and the psychology of moral judgments.
The Impact of Western Sanctions on Putin's War
Authors: Chyzh Olga V. 
Published: March 2022

AbstractIn response to Putin's invasion of Ukraine, the West imposed a package of unprecedented sanctions that has failed to generate meaningful domestic backlash against Putin's war. Leveraging extant research on the survival of authoritarian regimes under economic sanctions, I show that their devastating economic costs notwithstanding, sanctions are unlikely to destabilize Putin's regime or pressure him to withdraw his troops from Ukraine. The key to explaining this outcome is to zero in on the incentive structure of the groups of individuals that make up Putin's inner circle.
Ediacaran survivors in the Cambrian: suspicions, denials and a smoking gun
Authors: Hoyal Cuthill Jennifer F 
Published: March 2022

AbstractThe relative timing of extinctions and originations is a foundation for reconstructing evolutionary causes. However, there has been a tendency to dismiss reported Ediacaran holdovers in favour of effective extinction around the Cambrian boundary. Here, focusing on the classically Ediacaran frondose biota (Petalonamae), I suggest four main reasons why proposed Ediacaran survivors have previously been denied the acceptance they deserve: denials based on mistaken identity, doppelgängers, a last gasp or dead clades walking. I then point to the lower Cambrian species Stromatoveris psygmoglena as a key example which simultaneously meets these objections. Collectively, Cambrian survivors are a ‘smoking gun’ showing that extinction of the classically Ediacaran frondose biota did not occur until at least 30 Ma after the end of the Ediacaran period, registered by phylogenetic petalonamid Thaumaptilon from the Burgess Shale. Therefore, to paraphrase Mark Twain, reports of their earlier demise have been greatly exaggerated. Causes of their ultimate extinction should instead be sought in their total range and diversity dynamics. Overall, the Ediacaran–Cambrian transition shows extremely low numbers of recorded survivors, but diversity dynamics are dominated by the Cambrian explosion. In this context, recorded occurrences for the classically Ediacaran frondose biota are compatible with at least two extinction events, one within a possible mass extinction near the Cambrian boundary, and later, their ultimate extinction in, or after, the middle Cambrian (Miaolingian Series, Wuliuan Stage). There is, however, no correlative basis for a causal link between the Cambrian transition and the effective or final demise of the classically Ediacaran soft-bodied biota.
Women’s migration to cities
Authors: Das Marjolijn , Boterman Willem R. , Karsten Lia , Latten Jan J. 
Published: March 2022

AbstractThis study investigates the consequences of female rural-urban migration with respect to their education, career, and relationship and family formation in the Netherlands. The study is based on four birth cohorts of Dutch women born in 1970-1973 in rural areas, comparing those who had migrated to urban areas before the age of 25 with those who had remained behind. Outcomes were measured at age 42. The data were derived from administrative registers available at Statistics Netherlands. The results show that female migration to cities served to increase women’s resources: they were more often university educated and had better paid jobs, in line with the idea of cities as socioeconomic escalators. The city also functioned as a relationship market with a relative abundance of men with resources. Both lower and university educated city women were more likely to be in a relationship with a highly educated man compared to their rural peers. However, lower educated women had an increased probability of being single at age 42 when they lived in cities at age 25. This was not the case for university educated women. In conclusion, for lower educated women urban migration may entail risks as well as benefits, especially with respect to family formation. University educated women on the other hand benefited both in terms of their own socioeconomic outcomes and in terms of their partners’ resources.
Digital Practices of Negotiation: Social Workers at the Intersection of Migration and Social Policies in Switzerland and Belgium
Authors: ANDREETTA SOPHIE , BORRELLI LISA MARIE 
Published: March 2022

AbstractPaperwork has always been a central part of bureaucratic work. Over the last few years, bureaucratic procedures have become increasingly standardised and digitalised. Based on interviews and ethnographic fieldwork within welfare offices in Switzerland and Belgium, we reflect on the way evidence is constructed within social policy and cases built for or against noncitizen welfare recipients in order to show how paper truths are established and challenged. The focus on digital practices within public policy implementation highlights how it contributes to enhanced control mechanisms on the implementation level and how migration law continues to guide welfare governance for noncitizens. This allows targeting of the most marginalised groups, whose rights to access state support are institutionally impeded. Through database information flows, official forms, paper reports and face-to-face meetings, we further show how a hybrid form of bureaucratic work emerges, where direct contact with the client is still key, yet highly influenced by standardisation processes.
An iterative algorithm for inverse displacement analysis of Hyper-redundant elephant’s trunk robot
Authors: Yuan Feifei , Zhao Yongjie , Zhang Yongxing , Zhang Xingwei , Lu Xinjian 
Published: March 2022

AbstractThis paper proposes an iterative algorithm to solve the inverse displacement for a hyper-redundant elephant’s trunk robot (HRETR). In this algorithm, each parallel module is regarded as a geometric line segment and point model. According to the forward approximation and inverse pose adjustment principles, the iteration process can be divided into forward and backward iteration. This iterative algorithm transforms the inverse displacement problem of the HRETR into the parallel module’s inverse displacement problem. Considering the mechanical joint constraints, multiple iterations are carried out to ensure that the robot satisfies the required position error. Simulation results show that the algorithm is effective in solving the inverse displacement problem of HRETR.
CONSENT, INTERACTION, AND THE VALUE OF SHARED UNDERSTANDING
Authors: Healey Richard 
Published: March 2022

ABSTRACTRecent years have seen a proliferation of philosophical work on consent. Within this body of work, philosophers often appeal to an account of the interests, values, or functions that underpin the power of consent. By far the most commonly cited value realized by the power of consent is the promotion and protection of the power-holder's autonomy. This focus on autonomy yields what I call the Gate Opener Model of consent, according to which the central valuable function of consent is to give the power-holder control over whether other people can act in certain ways. In this article, I argue that the Gate Opener Model of consent is inadequate. I then defend an alternative Relational Model of consent, according to which a central valuable function of consent is to enable a non-instrumentally valuable form of interaction between people.
Retail food environment in a Brazilian metropolis over the course of a decade: evidence of restricted availability of healthy foods
Authors: Justiniano Irene Carolina Sousa , de Menezes Mariana Carvalho , Mendes Larissa Loures , Pessoa Milene Cristine 
Published: March 2022

AbstractObjective:To evaluate changes in the retail food environment profile in a Brazilian metropolis over a 10-year period.Design:An ecological study was conducted in the city of Belo Horizonte, Minas Gerais, Brazil. The addresses of formal food establishments were geocoded and classified according to their sold-food profile. Density changes were analysed according to neighbourhood, population size, income level and geospatial distribution.Setting:Totally, 468 neighbourhoods in the city of Belo Horizonte, Minas Gerais, Brazil.Participants:Totally, 83 752 formal food establishments registered for operation in any one or more of those years: 2008, 2011, 2015 and 2018.Results:There was an increase in unhealthy establishments (154 %), followed by mixed (51 %) and healthy establishments (32 %), during the period evaluated, in addition to an increase in density according to income categories. There was a higher proportion of unhealthy establishments in relation to healthy establishments, indicating worsening of the community food environment over time.Conclusions:Over the course of 10 years, changes in the neighbourhood’s food environment were unfavourable for adequate access to healthy foods in lower-income neighbourhoods. The findings reinforce the need for interventions aimed at increasing the availability of businesses that offer healthy food in the city.
High-Energy Electron Scattering in Thick Samples Evaluated by Bright-Field Transmission Electron Microscopy, Energy-Filtering Transmission Electron Microscopy, and Electron Tomography
Authors: Hayashida Misa , Malac Marek 
Published: March 2022

Energy-filtering transmission electron microscopy (TEM) and bright-field TEM can be used to extract local sample thickness $t$ and to generate two-dimensional sample thickness maps. Electron tomography can be used to accurately verify the local $t$. The relations of log-ratio of zero-loss filtered energy-filtering TEM beam intensity ($I_{{\rm ZLP}}$) and unfiltered beam intensity ($I_{\rm u}$) versus sample thickness $t$ were measured for five values of collection angle in a microscope equipped with an energy filter. Furthermore, log-ratio of the incident (primary) beam intensity ($I_{\rm p}$) and the transmitted beam $I_{{\rm tr}}$ versus $t$ in bright-field TEM was measured utilizing a camera before the energy filter. The measurements were performed on a multilayer sample containing eight materials and thickness $t$ up to 800 nm. Local thickness $t$ was verified by electron tomography. The following results are reported:• The maximum thickness $t_{{\rm max}}$ yielding a linear relation of log-ratio, $\ln ( {I_{\rm u}}/{I_{{\rm ZLP}}})$ and $\ln ( {I_{\rm p}}/{I_{{\rm tr}}} )$, versus $t$.• Inelastic mean free path ($\lambda _{{\rm in}}$) for five values of collection angle.• Total mean free path ($\lambda _{{\rm total}}$) of electrons excluded by an angle-limiting aperture.• $\lambda _{{\rm in}}$ and $\lambda _{{\rm total}}$ are evaluated for the eight materials with atomic number from $\approx$10 to 79.The results can be utilized as a guide for upper limit of $t$ evaluation in energy-filtering TEM and bright-field TEM and for optimizing electron tomography experiments.
POD Nanozyme optimized by charge separation engineering for light/pH activated bacteria catalytic/photodynamic therapy
Authors: Cao Changyu , Zhang Tingbo , Yang Nan , Niu Xianghong , Zhou Zhaobo , Wang Jinlan , Yang Dongliang , Chen Peng , Zhong Liping , Dong Xiaochen , Zhao Yongxiang 
Published: March 2022

AbstractThe current feasibility of nanocatalysts in clinical anti-infection therapy, especially for drug-resistant bacteria infection is extremely restrained because of the insufficient reactive oxygen generation. Herein, a novel Ag/Bi2MoO6 (Ag/BMO) nanozyme optimized by charge separation engineering with photoactivated sustainable peroxidase-mimicking activities and NIR-II photodynamic performance was synthesized by solvothermal reaction and photoreduction. The Ag/BMO nanozyme held satisfactory bactericidal performance against methicillin-resistant Staphylococcus aureus (MRSA) (~99.9%). The excellent antibacterial performance of Ag/BMO NPs was ascribed to the corporation of peroxidase-like activity, NIR-II photodynamic behavior, and acidity-enhanced release of Ag+. As revealed by theoretical calculations, the introduction of Ag to BMO made it easier to separate photo-triggered electron-hole pairs for ROS production. And the conduction and valence band potentials of Ag/BMO NPs were favorable for the reduction of O2 to ·O2−. Under 1064 nm laser irradiation, the electron transfer to BMO was beneficial to the reversible change of Mo5+/Mo6+, further improving the peroxidase-like catalytic activity and NIR-II photodynamic performance based on the Russell mechanism. In vivo, the Ag/BMO NPs exhibited promising therapeutic effects towards MRSA-infected wounds. This study enriches the nanozyme research and proves that nanozymes can be rationally optimized by charge separation engineering strategy.
Pre-clinical safety and therapeutic efficacy of a plant-based alkaloid in a human colon cancer xenograft model
Authors: Freeling Jessica L. , Scholl Jamie L. , Eikanger Morgan , Knoblich Cole , Potts Rashaun A. , Anderson David J. , Rower Joseph E. , Farjoo Mohammad Hadi , Zhao Haotian , Pillatzki Angela , Rezvani Khosrow 
Published: March 2022

AbstractA high-throughput drug screen revealed that veratridine (VTD), a natural plant alkaloid, induces expression of the anti-cancer protein UBXN2A in colon cancer cells. UBXN2A suppresses mortalin, a heat shock protein, with dominant roles in cancer development including epithelial–mesenchymal transition (EMT), cancer cell stemness, drug resistance, and apoptosis. VTD-dependent expression of UBXN2A leads to the deactivation of mortalin in colon cancer cells, making VTD a potential targeted therapy in malignant tumors with high levels of mortalin. VTD was used clinically for the treatment of hypertension in decades past. However, the discovery of newer antihypertensive drugs and concerns over potential neuro- and cardiotoxicity ended the use of VTD for this purpose. The current study aims to determine the safety and efficacy of VTD at doses sufficient to induce UBXN2A expression in a mouse model. A set of flow-cytometry experiments confirmed that VTD induces both early and late apoptosis in a dose-dependent manner. In vivo intraperitoneal (IP) administration of VTD at 0.1 mg/kg every other day (QOD) for 4 weeks effectively induced expression of UBXN2A in the small and large intestines of mice. Liquid chromatography–tandem mass spectrometry (LC–MS/MS) assays on tissues collected from VTD-treated animals demonstrated VTD concentrations in the low pg/mg range. To address concerns regarding neuro- and cardiotoxicity, a comprehensive set of behavioral and cardiovascular assessments performed on C57BL/6NHsd mice revealed that VTD generates no detectable neurotoxicity or cardiotoxicity in animals receiving 0.1 mg/kg VTD QOD for 30 days. Finally, mouse xenograft experiments in athymic nude mice showed that VTD can suppress tumor growth. The main causes for the failure of experimental oncologic drug candidates are lack of sufficient safety and efficacy. The results achieved in this study support the potential utility of VTD as a safe and efficacious anti-cancer molecule.
Losartan protects human stem cell-derived cardiomyocytes from angiotensin II-induced alcoholic cardiotoxicity
Authors: Song Yuanxiu , Li Hongxia , Ma Shuhong , Zhu Min , Lu Wen-jing , Lan Feng , Cui Ming 
Published: March 2022

AbstractAlcoholic cardiomyopathy (ACM) is a myocardial injury caused by long-term heavy drinking. Existing evidence indicates that high levels of oxidative stress are the key to pathological cardiomyopathy caused by long-term exposure to high concentrations of alcohol, while angiotensin II (AngII) and its type 1 receptor (AT1R) play an important role in excessive drinking. Whether oxidative stress-induced damage in ACM is related to AngII and AT1R is unclear, and the effects of alcohol on the electrophysiology of myocardial cells have not been reported. Most existing studies have used animal models. This study established an in vitro model of ACM based on human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). The transcriptional profiling of alcohol treatment was performed by RNA-seq analysis. The role of oxidative stress, the expression of nicotinamide adenine dinucleotide phosphate oxidase (NOX), and the role of AngII and AT1R in the overactivation of oxidative stress were studied using fluorescent labeling, Western blotting, and high-content quantitative analysis. Real-time cell analysis(RTCA) and microelectrode array (MEA) were used to continuously monitor myocardial beating, observe the effects of alcohol on myocardial electrophysiological activity, and clarify the protective effects of the AT1R blocker losartan on ACM. We found that AngII and AT1R contribute to the effects of alcohol on the myocardium through oxidative stress damage, the mechanism of which may be achieved by regulating NOX.