bluuebunny/crossref_metadata_2025_split huggingface dataset:
OPTIMASI PEMANFAATAN LUMPUR AKTIF UNTUK MENURUNKAN KADAR COD MENGGUNAKAN METODE DESAIN EKSPERIMEN TAGUCHI
Authors: Teguh Riyanto  , Nur Muflihah  , Andhika Mayasari  , Fatma Ayu Nuning Farida Afiatna  
Published: October 2022

Abstract
PT. XYZ is a private sugar factory in Lamongan Regency, East Java. The resulting product is sugar, besides that the sugar production process cannot be separated from liquid waste. PT. XYZ often has problems in the treatment of WWTP (Wastewater Treatment Plant) at the input in the BE pond (Equalization Tank). Influent in the BE pond (Equalization Tank) often occurs levels of COD (Chemical Oxygen Demand) that do not match the company's quality standards because the influent input is sometimes too large. The purpose of this study was to improve the quality of the influent product to match the company's quality standards with aspects of activated sludge utilization in BE ponds (Equalization Tank). The taguchi method is used as a method to improve and improve quality and analyze the factors that influence the quality of the influent, including the volume of activated sludge, the length of the aerator running, the volume of waste, the interval between activated sludge added and observed. Taguchi standard orthogonal matrix L8(27) used the objective function 'the value is getting smaller (closer to the desired 0)'. The results of the analysis of variance (ANOVA) obtained that the dominant factor affecting the quality of the influent was the volume of waste (C), while based on the Taguchi method, the most optimal experimental results resulted in a combination of 100 ml activated sludge volume, 5 hours aerator running time, 1 liter waste volume, the gap between activated sludge was added and observed for 5 hours.
Biomechanical mechanism of reduced aspiration by the Passy-Muir valve in tracheostomized patients following acquired brain injury: Evidences from subglottic pressure
Authors: Han Xiaoxiao , Ye Qiuping , Meng Zhanao , Pan Dongmei , Wei Xiaomei , Wen Hongmei , Dou Zulin 
Published: October 2022

ObjectiveAspiration is a common complication after tracheostomy in patients with acquired brain injury (ABI), resulting from impaired swallowing function, and which may lead to aspiration pneumonia. The Passy-Muir Tracheostomy and Ventilator Swallowing and Speaking Valve (PMV) has been used to enable voice and reduce aspiration; however, its mechanism is unclear. This study aimed to investigate the mechanisms underlying the beneficial effects of PMV intervention on the prevention of aspiration.MethodsA randomized, single-blinded, controlled study was designed in which 20 tracheostomized patients with aspiration following ABI were recruited and randomized into the PMV intervention and non-PMV intervention groups. Before and after the intervention, swallowing biomechanical characteristics were examined using video fluoroscopic swallowing study (VFSS) and high-resolution manometry (HRM). A three-dimensional (3D) upper airway anatomical reconstruction was made based on computed tomography scan data, followed by computational fluid dynamics (CFD) simulation analysis to detect subglottic pressure.ResultsThe results showed that compared with the non-PMV intervention group, the velopharynx maximal pressure (VP-Max) and upper esophageal sphincter relaxation duration (UES-RD) increased significantly (P &lt; 0.05), while the Penetration-Aspiration Scale (PAS) score decreased in the PMV intervention group (P &lt; 0.05). Additionally, the subglottic pressure was successfully detected by CFD simulation analysis, and increased significantly after 2 weeks in the PMV intervention group compared to the non-PMV intervention group (P &lt; 0.001), indicating that the subglottic pressure could be remodeled through PMV intervention.ConclusionOur findings demonstrated that PMV could improve VP-Max, UES-RD, and reduce aspiration in tracheostomized patients, and the putative mechanism may involve the subglottic pressure.Clinical trial registration[http://www.chictr.org.cn], identifier [ChiCTR1800018686].
Dynamics of stand productivity in Moso bamboo forest after strip cutting
Authors: Zheng Yaxiong , Fan Shaohui , Zhou Xiao , Zhang Xuan , Guan Fengying 
Published: October 2022

Strip cutting can effectively reduce the cutting cost of bamboo forests and promote the transformation and upgradation of bamboo forests through mechanization and modernization. Despite the rapid accumulation of Moso bamboo biomass, the dynamics of five years changes in stand characteristics and productivity after cutting remain unclear. This is critical for formulating efficient bamboo forest management measures. In this paper, plots with an 8 m width strip cut (SC) and respective reserved belts (RB) were selected as the research object, and the traditional management forest (CK) as control. The dynamic characteristics of stand, biomass distribution pattern, and productivity change in the different treatment plots were studied for 5 years after cutting. The results showed that cutting increased the number of shoots and new bamboo, and decreased the diameter at breast height, height to crown base, and height of new bamboo (p&lt;0.05). Cutting reduces the productivity of both SC and RB, and allocates more biomass to the bamboo leaves to capture light in SC (p&lt;0.05). Over time, the characteristics of new bamboo in SC reached the level of CK, and the density of standing bamboo, and productivity, were higher than those in CK. However, the number and productivity of new bamboo decreased significantly in the RB (p&lt;0.05), which reflected the density restriction effect of bamboo forest. Further analysis showed that the increase in productivity in SC and CK was mainly from Moso bamboo at II and III “du”, which positively correlated with the soil contents of total nitrogen, total phosphorus, and available phosphorus. It was suggested that after three On-year restorations, the SC could reach the level of CK, however it is necessary to density manage RB from the second On-year after cutting.
The relationship between eHealth literacy, social media self-efficacy and health communication intention among Chinese nursing undergraduates: A cross-sectional study
Authors: Sun Huiping , Qian Lin , Xue Mengxin , Zhou Ting , Qu Jiling , Zhou Jingxin , Qu Junchao , Ji Siqi , Bu Yuan , Hu Yicheng , Wu Shaung , Chen Yuhui , You Jiachun , Liu Yongbing 
Published: October 2022

BackgroundWith the popularization of the Internet, it has become possible to widely disseminate health information via social media. Medical staff's health communication through social media can improve the public's health literacy, and improving the intention of health communication among nursing undergraduates is of great significance for them to actively carry out health communication after entering clinical practice.ObjectiveTo explore the relationship among eHealth literacy, social media self-efficacy, and health communication intention and to determine the mediating role of social media self-efficacy in the relationship between eHealth literacy and health communication intention.DesignA cross-sectional descriptive correlation design was used in this study.ParticipantsStratified cluster sampling was used to select 958 nursing students from four nursing colleges in Jiangsu Province, China, from June to July 2021.MethodsData were collected using the eHealth Literacy Scale, the Social Media Self-efficacy Scale, and the Health Communication Intention Questionnaire. Sociodemographic data were also collected. Correlation analysis and regression analysis were used to determine the relationship between eHealth literacy, social media self-efficacy, and health communication intention.ResultsHealth communication intention is positively correlated with eHealth literacy and social media self-efficacy. There is a significant positive correlation between eHealth literacy and health communication intention (β = 0.57, p &lt; 0.001), and social media self-efficacy played a mediating role in the influence of eHealth literacy on health communication intention (the mediating effect accounted for 37.2% of the total effect).ConclusionThe study found that eHealth literacy and social media self-efficacy had an impact on health communication intention. Because there is a correlation between eHealth literacy and social media self-efficacy and health communication intention, in order to promote health communication intention of nursing students, it is also important to cultivate eHealth literacy and social media self-efficacy of nursing students. In view of these results, targeted educational programs must be developed to improve eHealth literacy and social media self-efficacy among nursing undergraduates, thereby promoting their health information transmission.
Green Synthesis of Chitosan Nanoparticles Using of Martynia annua L. Ethanol Leaf Extract and Their Antibacterial Activity
Authors: Duraisamy Narayanasamy , Dhayalan Sangeetha , Shaik Mohammed Rafi , Shaik Althaf Hussain , Shaik Jilani P. , Shaik Baji 
Published: October 2022

The herbal-based drug isolation-related research has increased recently around the globe. Accordingly, the current study was designed to evaluate the phytochemical content of ethanol extract of Martynia annua and its chitosan nanoparticles (MA-CNPs) antibacterial activity against bacterial pathogens such as Bacteroides fragilis, Streptococcus oralis MTCC 2696, Propionibacterium acnes MTCC 1951, Pseudomonas aeruginosa MTCC 424, Staphylococcus aureus MTCC 2940, E. coli MTCC 443, Bacillus cereus MTCC 441, Streptococcus mutans MTCC 890, Aeromonas hydrophila MTCC 12301, and Streptococcus faecalis by agar well diffusion methods. The obtained results showed that the ethanol extract of M. annua contains more pharmaceutically valuable phytochemicals than other solvent extracts and its mediated chitosan nanoparticles showed effective antibacterial activities. The ethanol extract also effectively reduced, capped, and stabilized the chitosan into MA-CNPs. The green synthesized MA-CNPs were characterized and confirmed through UV-visible spectrophotometer, FT-IR, SEM, and DLS analyses. The MA-CNPs exhibited considerable antibacterial activity in the order of Bacteroides fragilis > Streptococcus oralis > Propionibacterium acnes > Pseudomonas aeruginosa > Staphylococcus aureus > E. coli > Bacillus cereus > Streptococcus mutans > Aeromonas hydrophila> Streptococcus faecalis. Finally, the results strongly recommended that the ethanol extract of M. annua-mediated chitosan nanoparticles could be considered an effective nanomaterial to control microbial pathogens. Further, therapeutical uses of MA-CNPs need in vitro and in vivo investigation.
Genome-Wide Identification of Strawberry C2H2-ZFP C1-2i Subclass and the Potential Function of FaZAT10 in Abiotic Stress
Authors: Li Hao , Yue Maolan , Jiang Leiyu , Liu Yongqiang , Zhang Nating , Liu Xiaoling , Ye Yuyun , Lin Ximeng , Zhang Yunting , Lin Yuanxiu , Li Mengyao , Wang Yan , Zhang Yong , Luo Ya , Wang Xiaorong , Chen Qing , Tang Haoru 
Published: October 2022

C2H2-type zinc finger proteins (C2H2-ZFPs) play a key role in various plant biological processes and responses to environmental stresses. In Arabidopsisthaliana, C2H2-ZFP members with two zinc finger domains have been well-characterized in response to abiotic stresses. To date, the functions of these genes in strawberries are still uncharacterized. Here, 126 C2H2-ZFPs in cultivated strawberry were firstly identified using the recently sequenced Fragaria × ananassa genome. Among these C2H2-ZFPs, 46 members containing two zinc finger domains in cultivated strawberry were further identified as the C1-2i subclass. These genes were unevenly distributed on 21 chromosomes and classified into five groups according to the phylogenetic relationship, with similar physicochemical properties and motif compositions in the same group. Analyses of conserved domains and gene structures indicated the evolutionary conservation of the C1-2i subclass. A Ka/Ks analysis indicated that the C1-2i members were subjected to purifying selection during evolution. Furthermore, FaZAT10, a typical C2H2-ZFP, was isolated. FaZAT10 was expressed the highest in roots, and it was induced by drought, salt, low-temperature, ABA, and MeJA treatments. It was localized in the nucleus and showed no transactivation activity in yeast cells. Overall, these results provide useful information for enriching the analysis of the ZFPs gene family in strawberry, and they provide support for revealing the mechanism of FaZAT10 in the regulatory network of abiotic stress.
Social Hierarchy Dictates Intestinal Radiation Injury in a Gut Microbiota-Dependent Manner
Authors: Zeng Xiaozhou , Liu Zhihong , Dong Yanxi , Zhao Jiamin , Wang Bin , Xiao Huiwen , Li Yuan , Chen Zhiyuan , Liu Xiaojing , Liu Jia , Dong Jiali , Fan Saijun , Cui Ming 
Published: October 2022

Social hierarchy governs the physiological and biochemical behaviors of animals. Intestinal radiation injuries are common complications connected with radiotherapy. However, it remains unclear whether social hierarchy impacts the development of radiation-induced intestinal toxicity. Dominant mice exhibited more serious intestinal toxicity following total abdominal irradiation compared with their subordinate counterparts, as judged by higher inflammatory status and lower epithelial integrity. Radiation-elicited changes in gut microbiota varied between dominant and subordinate mice, being more overt in mice of higher status. Deletion of gut microbes by using an antibiotic cocktail or restructuring of the gut microecology of dominant mice by using fecal microbiome from their subordinate companions erased the difference in radiogenic intestinal injuries. Lactobacillus murinus and Akkermansia muciniphila were both found to be potential probiotics for use against radiation toxicity in mouse models without social hierarchy. However, only Akkermansia muciniphila showed stable colonization in the digestive tracts of dominant mice, and significantly mitigated their intestinal radiation injuries. Our findings demonstrate that social hierarchy impacts the development of radiation-induced intestinal injuries, in a manner dependent on gut microbiota. The results also suggest that the gut microhabitats of hosts determine the colonization and efficacy of foreign probiotics. Thus, screening suitable microbial preparations based on the gut microecology of patients might be necessary in clinical application.
TcJAV3–TcWRKY26 Cascade Is a Missing Link in the Jasmonate-Activated Expression of Taxol Biosynthesis Gene DBAT in Taxus chinensis
Authors: Chen Li , Wu Ling , Yang Liu , Yu Haiyang , Huang Pingliang , Wang Yuehua , Yao Ruifeng , Zhang Meng 
Published: October 2022

Jasmonates (JAs) are the most effective inducers for the biosynthesis of various secondary metabolites. Currently, jasmonate ZIM domain (JAZ) and its interactors, such as MYC2, constitute the main JA signal transduction cascade, and such a cascade fails to directly regulate all the taxol biosynthesis genes, especially the rate-limit gene, DBAT. Another JA signaling branch, JAV and WRKY, would probably fill the gap. Here, TcJAV3 was the closest VQ-motif-containing protein in Taxus chinensis to AtJAV1. Although TcJAV3 was overexpressed in AtJAV1 knockdown mutant, JAVRi17, the enhanced disease resistance to Botrytis cinerea caused by silencing AtJAV1 was completely recovered. The results indicated that TcJAV3 indeed transduced JA signal as AtJAV1. Subsequently, TcWRKY26 was screened out to physically interact with TcJAV3 by using a yeast two-hybrid system. Furthermore, bimolecular fluorescence complementation and luciferase complementary imaging also confirmed that TcJAV3 and TcWRKY26 could form a protein complex in vivo. Our previous reports showed that transient TcWRKY26 overexpression could remarkably increase DBAT expression. Yeast one-hybrid and luciferase activity assays revealed that TcWRKY26 could directly bind with the wa-box of the DBAT promoter to activate downstream reporter genes. All of these results indicated that TcWRKY26 acts as a direct regulator of DBAT, and the TcJAV3–TcWRKY26 complex is actually another JA signal transduction mode that effectively regulates taxol biosynthesis in Taxus. Our results revealed that JAV–WRKY complexes directly regulated DBAT gene in response to JA stimuli, providing a novel model for JA-regulated secondary metabolism. Moreover, JAV could also transduce JA signal and function non-redundantly with JAZ during the regulation of secondary metabolisms.
DhDIT2 Encodes a Debaryomyces hansenii Cytochrome P450 Involved in Benzo(a)pyrene Degradation—A Proposal for Mycoremediation
Authors: Padilla-Garfias Francisco , Sánchez Norma Silvia , Calahorra Martha , Peña Antonio 
Published: October 2022

Pollutants, such as polycyclic aromatic hydrocarbons (PAHs), e.g., benzo(a)pyrene (BaP), are common components of contaminating mixtures. Such compounds are ubiquitous, extremely toxic, and they pollute soils and aquatic niches. The need for new microorganism-based remediation strategies prompted researchers to identify the most suitable organisms to eliminate pollutants without interfering with the ecosystem. We analyzed the effect caused by BaP on the growth properties of Candida albicans, Debaryomyces hansenii, Rhodotorula mucilaginosa, and Saccharomyces cerevisiae. Their ability to metabolize BaP was also evaluated. The aim was to identify an optimal candidate to be used as the central component of a mycoremediation strategy. The results show that all four yeast species metabolized BaP by more than 70%, whereas their viability was not affected. The best results were observed for D. hansenii. When an incubation was performed in the presence of a cytochrome P450 (CYP) inhibitor, no BaP degradation was observed. Thus, the initial oxidation step is mediated by a CYP enzyme. Additionally, this study identified the D. hansenii DhDIT2 gene as essential to perform the initial degradation of BaP. Hence, we propose that D. hansenii and a S. cerevisiae expressing the DhDIT2 gene are suitable candidates to degrade BaP in contaminated environments.
An Enhanced Bounding Surface Model for Modelling Various Cyclic Behaviour of Clay
Authors: Wang Junxiang , Xotta Giovanna , De Marchi Nico , Salomoni Valentina 
Published: October 2022

Many results from cyclic triaxial experiments indicate that porous media, such as clays, exhibit various long-term behaviours under different cyclic stress ratios (CSRs). These can be classified into three main categories, namely, cyclic shakedown, cyclic stable and cyclic failure. Modelling these soil deformation responses, along with pore pressure and other fundamental cyclic aspects, such as closed hysteresis cycles and degradation, is still an open challenge, and research to date is limited. In order to properly describe and capture these characteristics, an enhanced plasticity model, based on the bounding surface and stress distance concepts, is developed here. In detail, a new uniform interpolation function of the plastic modulus, suitable for all loading stages, is proposed, and a new damage factor associated with the plastic shear strain and the deformation type parameter, is also incorporated into the plastic modulus. Accordingly, cyclic shakedown and cyclic failure can be distinguished, and degradation is achieved. Closed hysteresis loops, typical of clays, are obtained through a radial mapping rule along with a moving projection centre, located by the stress reversal points. Comparisons between the obtained numerical results and the experimental ones from literature confirm the suitability of the constitutive approach, which is capable of correctly capturing and reproducing the key aspects of clays’ cyclic behaviour.
The Source Structure Design of the Rotating Magnetic Beacon Based on Phase-Shift Direction Finding System
Authors: Li Bo , Yang Binfeng , Xiang Fenghua , Guo Jiaojiao , Li Hailin 
Published: October 2022

Target azimuth information can help further improve the accuracy of magnetic orientation, but the current periodic magnetic field generated by the magnetic beacon is multivalued, so it is not suitable for azimuth measurement. According to the distribution of a rotating magnetic field and the phase angle measuring principle, we put forward a new magnetic source structure design of a multiple rotating permanent magnet array by adjusting the spacing d, the rotating speed ω and the initial rotation angle φ, and then verified the mathematical model using COMSOL simulation software. A triple structure was obtained by comparison (d3=3d1=3d2=43 m, d3=3d1=3d2=43 m, φ1=0, φ2=4π5 rad. φ3=π rad), which can produce a strong characteristic magnetic signal similar to a heart-shaped field pattern. Finally, a signal transceiver system was set up for the experiment. The experimental result shows that the waveform of the magnetic signal generated by the real beacon meets the requirement of having a unique maximum value and good directivity within a period, which proves the practical application effect of the structure.
A contribuição da psicologia histórico-cultural para a educação escolar de estudantes com espectro autista- TEA
Authors: De Faria Juliany , Alves Veronice Suriano 
Published: October 2022

Este artigo é resultado de estudos teóricos e objetiva refletir sobre o desenvolvimento do psiquismo e das funções psicológicas superiores dos estudantes com espectro autista, por meio da mediação dos professores. O trabalho visa contribuir também com o processo de formação continuada dos professores que atuam com essa demanda. Para tanto, o estudo em questão está pautado no referencial teórico da psicologia histórico-cultural proposto por Vygotsky e outros autores que defendem esta perspectiva. Para desenvolver o trabalho, utilizou-se da pesquisa bibliográfica de produções científicas que abordam a temática.
Novas aptidões tecnológicas para micro e pequenas empresas
Authors: Rocha Gustavo Fernandes Paula , Naves Diones da Silva , Dutra Júlio Afonso Alves 
Published: October 2022

Indubitavelmente a tecnologia facilitou o dia a dia das pessoas, trazendo melhores formas de organizar dados (como pelos computadores), comunicação (via celulares, tablets, etc.), informações em tempo real, conhecimento do que se passa no mundo, entretenimento, entre tantas outras coisas. Os mecanismos tecnológicos podem auxiliar no planejamento, na produtividade e no vínculo com o cliente e com seus colaboradores no cotidiano empresarial. Assim sendo, o presente trabalho tem como objetivo tratar das novas aptidões tecnológicas para micro e pequenas e empresas, para tal, foi efetuada uma pesquisa bibliográfica de natureza qualitativa sobre o tema A cultura da empresa necessita mudar, a valorização e a gestão de pessoas precisam mudar. Inovar não é apenas sobre tecnologia, é inovar as formas de administrar. Mas como as aptidões tecnológicas estão de fato presentes nas micro e pequenas empresas? Pode-se observá-las nos sistemas eficazes de antivírus, backup, gestão empresarial, vendas online, presença digital, infraestrutura e softwares que facilitam o cotidiano. O sucesso está aliado ao uso estratégico de todas as informações que uma empresa possui. Conclui-se que o acesso à informação e a tecnologia oferece ao pequeno empreendedor a possibilidade de inovar, melhor alocação de recursos, melhor identificação de riscos, além de aumentar a sua produtividade, agilidade como um todo, maior planejamento em todas as tarefas, otimização de custos, diminuir o tempo de execução das tarefas, maior rapidez na resposta ao cliente, monitoramento do cliente, com assistência de sua conduta no que tange ao negócio e seu sentimento no que tange à marca nas mídias sociais.