bluuebunny/crossref_metadata_2025_split huggingface dataset:
Plasma Exosomal Proteins Predict the Prognosis of Acute ST-segment Elevation Myocardial Infarction
Authors: Li Hai-Yang , Wang Hong-Jiang , Du Xiang-Peng , Liu Jia-Peng , Yang Xin-Chun , Zheng Mei-Li 
Published: June 2022

Abstract
Acute ST-segment elevation myocardial infarction (ASTEMI) leads to great morbidity and mortality, even after immediate reperfusion therapy by primary percutaneous coronary intervention (PCI). Plasma exosomal proteins detected in the acute stage are supposed to affect the outcomes of ASTEMI. The present study collected ASTEMI patients with ischemic time around 6 hours and underwent successful emergency PCI, used exosomal proteomics to identify the plasma exosomal proteins, and performed a 1-year follow-up on ASTEMI outcomes. We observed that plasma exosomes concentration significantly decreased in ASTEMI after PCI than before it. Receiver operating characteristic (ROC) curve analysis revealed that several plasma exosomal proteins detected were strong predictors for coronary reintervention, which were revalidated in Cox regressions; while several plasma exosomal proteins were strong predictors for heart failure, which were revalidated in logistic regressions. The protein–protein network interactions and literature review suggest that plasma exosomal proteins might correlate with ASTEMI prognosis though involving in lipid and carbohydrate metabolism, regulation of cardiac muscle contraction, inflammation, platelet activation, or ferroptosis. Our results provide potential preventive and therapeutic targets for ASTEMI outcomes after PCI.
Writing Self-Efficacy in Post-Secondary Students: A Systematic Review
Authors: Mitchell Kim M. , Zumbrunn Sharon , Demczuk Lisa , Berry Danielle 
Published: June 2022

Abstract
In this systematic review, we examine studies of writing self-efficacy conducted with post-secondary students, published between 1984 and 2021. We aimed to examine the methodological choices, writing contexts, and types of pedagogies explored in studies of writing self-efficacy with post-secondary students, and to summarize the practical implications noted across the included studies. A total of 56 studies met eligibility criteria. All studies were quantitative in nature, conducted in English language settings, focused on students in college or graduate school, and included at least one writing self-efficacy measure. Across the 56 studies, the three variables most commonly appearing alongside writing self-efficacy were writing performance, writing apprehension or writing anxiety, and change in writing self-efficacy over time. Writing contexts and measures of writing self-efficacy varied greatly across the included studies. Common practical implications noted across studies included students’ tendency to overinflate their writing self-efficacy, recognition of the developmental nature of writing ability, the importance of teacher attitudes and instructional climate, the power of feedback, and approaches to teaching and guiding writing. Based on this review, we see several directions for future research: 1) a need for longitudinal studies; 2) a need for research to be situated; 3) a need to consider the impacts of diversity in writing self-efficacy research; and 4) the need for consistent use of strong multidimensional measures of writing self-efficacy.
Harvesting distance effect on tree species diversity in traditional agroforestry landscape: A case of Vhembe Biosphere Reserve in South Africa
Authors: Makhubele Lucky , Araia Mulugeta G , Chirwa Paxie W 
Published: June 2022

Abstract
Traditional agroforestry has been recognised to contribute to biodiversity conservation; however, biodiversity strategies often lack information about drivers of tree species diversity loss, which is crucial for decision-making. Anthropogenic disturbance has positive and negative effects on tree species richness and diversity. This study was conducted in Vhembe Biosphere Reserve, Limpopo Province, and used distance from the nucleus of the community to the forest as a parameter to assess tree species richness and diversity. Vegetation data were collected using three transects of 150 m in each distance level and sampled a total area of 1000 m2 by sampling five rectangular plots of \(20m x 10m \left(200{m}^{2}\right)\). Data analysis was conducted using Chao1, PERMANOVA, nMDS, PERMDISP, DISTLIM, dbRDA and SIMPER. The findings are in consonant with distance decay of community similarity hypotheses, with estimated tree species richness of 76, 93 and 95 species in an immediate distance, intermediate distance and far distance, respectively. Moreover, the highest species variation was observed at an intermediate distance, which indicates that there is greater species composition at an intermediate distance compared to immediate and far distances. The results confirm that the distance and associated factors have major detrimental effects on tree species richness and biodiversity in traditional agroforestry landscapes. Harvesting of provisioning ecosystem services is found and known to be extremely high in the study area. Effective interventions such as planting native trees and conserving the existing vegetation must be implemented to reduce and halt overexploitation.
Patterns of skin temperature during exercise that act as a thermal controller of the body
Authors: Park Young Hwan , Kim Young Ha , Suh Seong Woo 
Published: June 2022

Abstract
Background: Many studies have suggested that skin temperature acts as a thermal controller of the body, but the results were varied depending on type of exercise, intensity, and duration. This study aimed to establish thermal control pattern of the body by investigating the systematic skin temperature response to a treadmill exercise and a crunch exercise.Methods: Ten male volunteers majoring in professional physical education participated for the study. Treadmill exercise and crunch exercise were performed to assess skin temperature response in whole-body exercise and selective abdominal muscle exercise, respectively. The body surface was categorized into 21 specific regions of interest (ROIs) and the skin temperatures of ROIs were measured with infrared thermography at before and after exercise.Results: All skin temperature except anterior forearm, anterior thigh, anterior genual, posterior arm, and posterior cubital regions of the treadmill exercise were significantly reduced after exercise (p < 0.05), and the degree of temperature reduction was 1.7 ± 1.1 ˚C. Among these regions, the pectoral, umbilical, and infrascapular regions showed significant temperature reduction compare to the other ROIs in both exercises (p < 0.05).Conclusion: A significant reduction of the skin temperature in the pectoral, umbilical, and infrascapular regions indicates that these regions may play an important role in thermally controlling of the body during exercise.Level of evidence: II
Dexmedetomidine for pain management and sedation in neonates and infants during intensive care
Authors: Tervonen Miikka , Cajanus Johanna , Kallio Merja , Huhtamäki Heikki , Peltoniemi Outi 
Published: June 2022

Abstract
Purpose: To assess the safety of continuous dexmedetomidine infusion in neonates and infants during intensive care. Methods: A register-based cohort study was conducted in the pediatric intensive care unit at Oulu University Hospital. The study population consisted of all children under 6 months of age who received dexmedetomidine during 2010–2016. Sixty percent of the 198 infants included in the study had congenital malformation, and 50% had undergone surgery. Adverse cardiorespiratory outcomes were defined as abnormal values of heart rate or blood pressure according to the Pediatric Early Warning Score (PEWS) Scale.Results: Neonates experienced severe bradycardia (16% vs. 12% in 1–3 months of age and 2% in those aged 3–6 months, p=0.015) and severe hypotension more often than older infants (43% vs. 11% in those aged 1–3 months and 28% in those aged 3–6 months, p=0.002). Logistic regression showed a dose-dependent increase in bradycardia and severe hypotension. Adverse cardiovascular events were managed with additional fluid boluses and discontinuation of the infusion. The overall dosage of dexmedetomidine was a risk factor for withdrawal symptoms. Conclusions: Adverse cardiovascular events were commonly noted during dexmedetomidine administration in neonates and infants. Increased attention should be paid to cardiovascular outcomes and withdrawal symptoms in the neonatal patients. Lower dexmedetomidine doses may be required during the sedation of neonates.
The Chemical Components of Dufour’s and Venom Gland of Camponotus japonicus (Hymenoptera, Formicidae)
Authors: Xu Wenjing , Zhao Mengqin , Tang Lingxiao , Ma Ruoqing , He Hong 
Published: June 2022

Abstract
Dufour’s and venom gland are the two most developed glands which connected with the female reproductive organs, and they play many important roles in defense, foraging, information exchange and reproduction of ants. Their main chemical secretions varied between ant species, even castes of the same ant species. In this study the chemical components of the Dufour’s and venom glands in different castes of Camponotus jamponicus (original worker, minor worker, major worker, gyne and queen) were analyzed by using gas chromatography–mass spectrometer (GC–MS) with two sample processing methods (Hexane solution method and solid-phase micro-extraction (SPME)). The secretion of Dufour’s gland is characterized with high ratio of alkanes and many kinds of alcohols, esters and alkenes, in which, n-Undecane is the dominant secretion in all castes except the original workers and its proportion significantly varies among castes. The secretion of venom gland mainly includes alkanes, acids, some ketones and alcohols, in which, Formic acid and n-Undecane are dominant components and their proportion shows obviously different among castes. Therefore, the chemical composition and the proportion of the main components of the two glands are significantly different among castes which should be closely related to the labor division in their social life. This study provides basic information for us to further understand the function of the two glands in the social life of ants.
Cadmium, Arsenic and Mineral Nutrients in Rice, and Potential Risks for Human Health in South China
Authors: Liu Qinghui , Lu Weisheng , Bai Cuihua , Xu Congzhuo , Ye Maozhi , Zhu Yongcong , Yao Lixian 
Published: June 2022

Abstract
Rice (Oryza sativa L.) is one of the most important staple food crop worldwide. For people fed on rice, toxic elements cadmium (Cd) and arsenic (As) and mineral nutrients in rice are pivotal to evaluate potential risks of harmful element intake and malnutrition. We collected rice samples of 208 cultivars (83 inbred and 125 hybrid) from fields in South China, and determined Cd, As, As species, and mineral elements in brown rice. Histochemistry analysis shows that Cd and As in brown rice were 0.26 ± 0.32 and 0.21 ± 0.08 mg·kg− 1, respectively. Inorganic As (iAs) was the dominative As species in rice. Brown rice Cd and iAs in 35.1% and 52.4% of the 208 cultivars exceeded rice Cd and iAs limits. Significant variations of rice subspecies and regions were found for Cd, As and mineral nutrients in brown rice (P < 0.05). Inbred rice has lower As uptake and more balanced mineral nutrition than hybrid species. Significant correlation was observed between Cd, As versus mineral elements like Ca, Zn, B and Mo (P < 0.05). Health risk assessment indicates that high risks of Cd intake and malnutrition, in particular to Ca, protein and Fe, can be caused by rice consumption in South China.
Characterization of low-density polyethylene (LDPE) films degraded using bacteria strains isolated from oil contaminated soil
Authors: Akhigbe Godswill E. , EnochOghene Adebisi E. , Olumurewa Kayode O. , Koleoso Olusegun , Ogbonna Ngozi D. 
Published: June 2022

Abstract

This study assessed the low-density polythene (LDPE) film degradation potential of microorganisms isolated from oil contaminated soil, and characterizing the LDPE films after degradation period by analyzing the morphological and chemical composition. The bacteria strains isolated from petroleum contaminated soils were used as bio-degraders for the analysis and isolates with great degradation activity were identified via 16S RNA gene amplification technique. The growth rates of the bacterial isolates and their LDPE utilization in the medium were monitored for 78 days, using UV spectrophotometry. Thereafter, the LDPE in the media were quantitatively and qualitatively analysed. Results obtained from weight loss measurement, scanning electron microscope (SEM) images and energy dispersal x-ray (EDX) revealed a reduction in weight, porosity and fragility of all the analyzed LDPE films that were subjected to bacteria degradation. Isolates with good degradation of LDPE films were identified as Proteus mirabilis (Accession number: MN124173.1) and Proteus mirabilis (Accession number: KY027145.1), having a weight loss of 89.72% and 71.80% respectively. The identification and utilization of potential LDPE microbial degraders are useful in the management of plastic waste, leading to a reduction in global plastic waste and a clean environment.
Metagenomic assessment of gut microbial communities and risk of severe COVID-19
Authors: Lai Peggy , Nguyen Long , Okin Daniel , Drew David , Battista Vincent , Jesudasen Sirus , Kuntz Thomas , Bhosle Amrisha , Thompson Kelsey , Reinicke Trenton , Lo Chun-Han , Woo Jacqueline , Caraballo Alexander , Berra Lorenzo , Vieira Jacob , Huang Ching-Ying , Adhikari Upasana Das , Kim Minsik , Sui Hui-Yu , Magicheva-Gupta Marina , McIver Lauren , Goldberg Marcia , Kwon Douglas , Huttenhower Curtis , Chan Andrew 
Published: June 2022

Abstract
The gut microbiome is a critical modulator of host immunity and is linked to the immune response to respiratory viral infections. However, few studies have gone beyond describing broad compositional alterations in severe COVID-19, defined as acute respiratory or other organ failure. We profiled 127 hospitalized patients with COVID-19 (n=79 with severe COVID-19 and 48 with moderate) who collectively provided 241 stool samples from April 2020 to May 2021 to identify links between COVID-19 severity and gut microbial taxa, their biochemical pathways, and stool metabolites. 48 species were associated with severe disease after accounting for antibiotic use, age, sex, and various comorbidities. These included significant in-hospital depletions of Fusicatenibacter saccharivorans and Roseburia hominis, each previously linked to post-acute COVID syndrome or “long COVID”, suggesting these microbes may serve as early biomarkers for the eventual development of long COVID. A random forest classifier achieved excellent performance when tasked with predicting whether stool was obtained from patients with severe vs. moderate COVID-19. Dedicated network analyses demonstrated fragile microbial ecology in severe disease, characterized by fracturing of clusters and reduced negative selection. We also observed shifts in predicted stool metabolite pools, implicating perturbed bile acid metabolism in severe disease. Here, we show that the gut microbiome differentiates individuals with a more severe disease course after infection with COVID-19 and offer several tractable and biologically plausible mechanisms through which gut microbial communities may influence COVID-19 disease course. Further studies are needed to validate these observations to better leverage the gut microbiome as a potential biomarker for disease severity and as a target for therapeutic intervention.
Assessment of Ground Water Potential Zone based on Multi-Criteria Decision making model and Geospatial Techniques: The case of Lemo Woreda and Hossana town, Hadiya Zone, Southern Nation Nationalities
Authors: Abe Mulugeta Wolde , Ersado Alemu Ersino 
Published: June 2022

Abstract
The objective of this paper is to assess and map groundwater potential zone in Lemo woreda and Hosana town by the integrating approach of Geospatial Techniques. For this purpose both primary and secondary data were used. Ground Control Points (GCP) were collected from Google earth; Digital Elevation Model (DEM) and Landsat 8 down loaded, besides, secondary data such as, soil data, rainfall, and Lithology were collected from different governmental institutions. Ground water controlling factors, namely, lithology, Geomorphology, slope, land use land cover (LULC), rainfall, lineaments, soil, and drainage density were generated. In order to map ground water potential area, Geographic Information System (GIS), Remote Sensing and Analytical Hierarchy Process (AHP) were used. AHP was used for computing weight for the parameters by comparing eight factors. The consistency ratio was less than 0.1(CR -0.03) which is acceptable weight to compute weighted overlay analysis in GIS environment .The weight derived for Rainfall, slope, Geomorphology, Soil type, lineaments density, drainage density , land use land cover (LULC) and lithology are:27%, 17%, 16%, 12 %, 9%, 8%, 6% and 5%, respectively, and the groundwater prospective of the area is qualitatively classified into five classes, namely, very high, High, moderate, low, and very low which account for 14.04%, 20.34%, 26.68%, 28.51%, and 10.44% the study area, respectively. The cross-validation of the resultant model was carefully carried out using spring, and water well data. The result tells most of spring and water well overlaying high and very high groundwater potential zones. As a result, the map generated using this platform could be used as a preliminary reference in selecting potential area for groundwater exploitation.
A Rare Coexistence : Poland's Syndrome and Cardiac Angiosarcoma
Authors: KIZILYEL Fatih , GUNAY Rafet , RUM Mehmet , YILMAZ Mehmet , KETENCI Bulend 
Published: June 2022

Abstract
Poland’s syndrome, a rare genetic disorder that accompany with malignancies, musculoskeletal disorders and cardiac and genitourinary syndromes. There is no any study that represent association of a Cardiac Angiosarcoma and Poland’s Syndrome. 24-year-old female patient previously diagnosed with Poland’s Syndrome admitted to our clinic with complaint of dyspnea. Diagnostic imaging reveals an irregular mass in the right atrium cavity. After succesful surgery, she was discharged uneventfully and 3rd month oncologic follow-up reveals none of residual mass.As a Cardiac Surgery Department, such a coexistence has not been diagnosed and managed before. We aimed to contribute to the literature with this presentation, for right and early diagnosis and management of possible new cases on the future.
The Structure of Forest Vegetation on Industrial Landfills of Different Ages
Authors: Gorozhanina Elena , Gura Dmitry , Sitkiewicz Patryk , Degtyarevskaya Tatyana 
Published: June 2022

Abstract
This work is dedicated to examining the soil and forest vegetation characteristics in the landfills of quarries of various ages and climatic conditions (Kuzbass, Mosbass, and Sokolovsky quarry). The work was based on the analysis of the statements for 2001–2021. In the Kuzbass region, pH values were found to have fallen to 5.0. A similar trend was seen in the area of the younger Mosbass and Sokolovsky quarries. The basal soil respiration rate career was extremely low (about 0.3 mg CO2/g of soil/h). The CO2 content in the carbonate ranges from 0.07 to 0.7%, with the higher figures observed in older Kuzbass rather than Mosbass and Sokolovsky quarry. Analysis of soil samples from three quarries revealed four species groups at sites associated with the prevalence of specific fractions, such as gravel, sand, silt, and stony soil. The dominant species present on the gravel substrate were Downy Birch, Common Hornbeam, European Oak, Siberian Spruce, Common Juniper, Siberian Larch, Common Pine, and Siberian Fir. Given that Kuzbass is the oldest open-pit mine, forest vegetation species dominate here in the surveyed areas, which is typical of gravel soils. Mosbass is also characterized by a diversity of similar species, though work on mineral mining there ended in 2009. Stony and sandy soil fractions predominated in the Sokolovsky quarry, although other studied substrates were also encountered.
Predicting health services utilization using a score of perceived barriers to medical care: evidence from rural Senegal
Authors: COSTE Marion , BOUSMAH Marwân-al-Qays 
Published: June 2022

Abstract
Background: Ensuring access to healthcare services is a key element to achieving the Sustainable Development Goal 3 of promoting healthy lives and well-being through Universal Health Coverage (UHC). However, in the context of low- and middle-income countries, most studies focused on financial protection measured through catastrophic health expenditures, or on health services utilization among specific populations exhibiting health needs (such as pregnancy or recent sickness). Methods: This study aims at building an individual score of perceived barriers to medical care (PBMC) in order to predict health services utilization (or non-utilization). We estimate the score on six items: (1) knowing where to go, (2) getting permission, (3) having money, (4) distance to the facility, (5) finding transport, and (6) not wanting to go alone, using individual data from 1787 adult participants living in rural Senegal. We build the score via a stepwise descendent explanatory factor analysis (EFA), and assess its internal consistency. Finally, we assess the predictive validity of the factor-based score by testing its association (univariate regressions) with a wide range of variables on determinants of healthcare-seeking and healthcare services utilization. Results: EFA yields a one-dimensional score combining items 3-6 with a 0.7 Cronbach’s alpha indicating good internal consistency. The score is strongly associated – p-values significant at the 5% level – with determinants of healthcare-seeking (including, but not limited to, sex, education, marital status, poverty, and distance to the health facility). Additionally, the score can predict non-utilization of health services at the household level, utilization and non-utilization of health services following an individual’s episode of illness, and utilization of health services during pregnancy and birth. These results are robust to the use of a different dataset.Conclusions: As a valid, sensitive, and easily documented individual-level indicator, the PBMC score can be a complement to regional or national level health services coverage to measure health services access and predict utilization. At the individual or household level, the PBMC score can also be combined with conventional metrics of financial risk protection such as CHE to comprehensively document deficits in, and progress towards UHC.