bluuebunny/crossref_metadata_2025_split huggingface dataset:
Establishment of an indicator framework for the transmission risk of the mountain-type zoonotic visceral leishmaniasis based on the Delphi-entropy weight method
Authors: Luo Zhuowei , Zhou Zhengbin , Hao Yuwan , Feng Jiaxin , Gong Yanfeng , Li Yuanyuan , Huang Yun , Zhang Yi , Li Shizhu 
Published: December 2022

Abstract
Background
Visceral leishmaniasis (VL) is one of the most important neglected tropical diseases. Although VL was controlled in several regions of China during the last century, the mountain-type zoonotic visceral leishmaniasis (MT-ZVL) has reemerged in the hilly areas of China in recent decades. The purpose of this study was to construct an indicator framework for assessing the risk of the MT-ZVL in China, and to provide guidance for preventing disease.

Methods
Based on a literature review and expert interview, a 3-level indicator framework was initially established in November 2021, and 28 experts were selected to perform two rounds of consultation using the Delphi method. The comprehensive weight of the tertiary indicators was determined by the Delphi and the entropy weight methods.

Results
Two rounds of Delphi consultation were conducted. Four primary indicators, 11 secondary indicators, and 35 tertiary indicators were identified. The Delphi-entropy weight method was performed to calculate the comprehensive weight of the tertiary indicators. The normalized weights of the primary indicators were 0.268, 0.261, 0.242, and 0.229, respectively, for biological factors, interventions, environmental factors, and social factors. The normalized weights of the top four secondary indicators were 0.122, 0.120, 0.098, and 0.096, respectively, for climatic features, geographical features, sandflies, and dogs. Among the tertiary indicators, the top four normalized comprehensive weights were the population density of sandflies (0.076), topography (0.057), the population density of dogs, including tethering (0.056), and use of bed nets or other protective measures (0.056).

Conclusions
An indicator framework of transmission risk assessment for MT-ZVL was established using the Delphi-entropy weight method. The framework provides a practical tool to evaluate transmission risk in endemic areas.
Depth perception between dots and the background face reduces trypophobic discomfort
Authors: Song Nanxin , Koyama Shinichi 
Published: December 2022

Abstract
Background
Studies have shown that viewing a cluster of dots evokes feelings of discomfort in viewers and that the discomfort becomes especially strong when the dots are placed on background images of human skin. This phenomenon has been explained by the physical properties and spatial and semantic relationships between the dots and the background. However, it was not known whether the perceived, as well as the physical, spatial relationships contributes to the generation of discomfort.

Methods
We evoked illusory depth perception between black dots and the background face by drawing shadow-like gray dots around the black dots, while keeping the same black dots at the same positions, and examined whether illusory depth perception could increase or decrease discomfort. In each trial, participants viewed one of the following types of facial images: (a) face-only (face without dots), (b) a cluster of black dots on the face, (c) a cluster of gray dots on the face, and (d) a cluster of black dots and shadow-like gray dots on the face. After seeing each picture, they evaluated how much discomfort they felt from viewing the picture using a Likert scale and reported whether they perceived depth between the dots and the face.

Results
Participants felt discomfort toward all three types of faces with dots, that is, faces with black dots, gray dots, and both. However, interestingly, participants felt less discomfort when both black and gray dots were presented on the face than when only black dots were presented. The participants perceived depth between the black dots and the face in 85% of the trials with black dots and shadow-like gray dots, and there was a significant correlation between discomfort and frequency of depth perception. However, in the trials with black dots only and gray dots only, they perceived depth in only 18% and 27% of the trials, respectively, and the correlations between the frequencies of depth perception and discomfort were not significant.

Conclusions
Our results suggest that the perceived spatial relationship, such as attached vs. separate, as well as the physical spatial relationship, contribute to the generation of discomfort.
Simulation of Germanium-on-Nothing cavity’s morphological transformation using deep learning
Authors: Jeong Jaewoo , Kim Taeyeong , Lee Jungchul 
Published: December 2022

AbstractUnique self-assembled germanium structures known as Germanium-on-Nothing (GON), which are fabricated via annealing, have buried multiscale cavities with different morphologies. Due to their unique sub-surface morphologies, GON structures are utilized in various applications including optoelectronics, micro-/nanoelectronics, and precision sensors. Each application requires different cavity shapes, and a simulation tool is able to determine the required annealing duration for a given shape. However, a theoretical simulation inevitably requires simplifications which limit its accuracy. Herein, to resolve such dependence on simplification, we introduce a deep learning-based method for simulating the transformation of sub-surface morhpology of GON over annealing. Namely, a deep learning model is trained to predict GON’s morphological transformation from 4 cross-sectional images acquired at different annealing times. Compared to conventional simulation schemes, our proposed deep learning-based simulation method is not only computationally efficient ($$\sim 10$$

∼
10

min) but also physically accurate with its use of empirical data.
Toward the replacement of conventional fertilizer with polyhalite in eastern China to improve peanut growth and soil quality
Authors: Tan Huiting , Cui Yuzhao , Liu Chang , Zeng Fanhe , Han Chuanhao , Zhang Huanyang , Fan Xiaohui , Mitchell Ross , Yan Dongyun , Zhang Daolai 
Published: December 2022

Abstract
Background
Polyhalite fertilizer application is an effective way to alleviate a shortage of potassium. This study explored the effects of polyhalite fertilizer application as a total or partial replacement for conventional potassium fertilizer to improve peanut growth and soil quality.

Results
The index of peanut yield and its economic benefits, the content and distribution of mineral nutrients in different organs, soil chemical properties, and rhizosphere microbial diversity in response to the treatments were examined. The results show that the M4P6T treatment (60% polyhalite fertilizer replacing potassium chloride as the base fertilizer, and 40% potassium chloride fertilizer applied as a topdressing) increased profit by 7.2% without affecting the yield. The M4P6T treatment significantly improved the accumulation and distribution of potassium, calcium and magnesium in the kernels compared with the M10B treatment (no polyhalite fertilizer; potassium chloride fertilizer only as the base fertilizer). Soil treated with polyhalite fertilizer had higher alpha-diversity values and greater relative abundance of microbes at the phylum and genus levels.

Conclusions
Partial substitution of polyhalite for potassium chloride improved soil quality and peanut growth more than did single applications of polyhalite and potassium chloride.

Graphical Abstract
A quantitative comparison of essential cardiovascular medicines from countries in the Southern African Development Community to the WHO model essential medicines list
Authors: Naicker Ian , Suleman Fatima , Perumal-Pillay Velisha Ann 
Published: December 2022

Abstract
Background
Globally, cardiovascular disease (CVD) is a leading cause of death and disproportionately affects low- and middle-income countries (LMICs). The WHO Model List of Essential Medicines (WHO EML) is a tool for improving accessibility and availability of medicines. This study compared the 2021 WHO EML CVDs basket of medicines with latest available national essential medicines list (NEMLs) for South Africa and 15 Southern African Development Community (SADC) countries to assess consistency in CVDs medicine listing.

Methods
This descriptive, desktop review study compared SADC NEMLs. A comparator list was extracted by combining cardiovascular medicines listed in the 2021 WHO EML for adults and children. SADC country NEMLs were obtained from the WHO Essential Medicines and Health Products Information Portal. Consistency of NEMLs was calculated as a percentage coverage of CVD medicines listed in the 2021 WHO EML. SA hospital and primary health care (PHC) level NEMLs were included as separate formularies.

Results
The SA hospital level NEML scored 70% consistency with the 2021 WHO EML. Tanzania (84%), Namibia (81%) and Angola (79%) scored the highest consistency. The mean consistency for SADC NEMLs was 66%. The lowest scoring country was Eswatini at 26%. The SA PHC NEML scored 35%. The least listed medicines were beta-blockers, angiotensin receptor blockers (ARBs), clopidogrel (43%) and paediatric formulations (furosemide (21%); digoxin (43%)). Individual antihypertensive medicines were most commonly listed. Botswana and Lesotho were the only countries to list a single pill combination (SPC) for the treatment of hypertension.

Conclusions
This comparison indicates that South Africa and most SADC countries are aligned with 2021 WHO EML recommendations. The inclusion of age-appropriate formulations for children as well as ARBs and SPC for the treatment of hypertension may improve patient adherence and cardiovascular outcomes in these countries. More frequent updates to NEMLs should improve consistency. NEMLs were not available for two countries, and these therefore did not form part of this study. Country health expenditure in ranking the consistency of NEMLs was not accounted for. LMICs adopting the essential medicine list strategy should consider imposing minimum consistency thresholds to the WHO EML to improve accessibility and availability of CVD medicines.
Trial registration: Not applicable.
Impact of the increase in the number of community pharmacists on their geographical distribution in Japan: a retrospective survey
Authors: Iguchi Kazuhiro , Ueyama Midori , Nishio Hiroto , Tamaki Hirofumi , Osanai Arihiro , Ino Yoko , Nonomura Kazuya , Horibe Megumi , Matsunaga Toshiyuki , Nakamura Mitsuhiro 
Published: December 2022

Abstract
Background
Appropriate distribution of health care resources is required to adjust regional disparities in the quality of health care. Besides, the number of community pharmacists in Japan has increased recently, but the impact of this increase on the distribution of community pharmacists is unknown. Thus, we aimed at investigating the effect of the increase in the number of community pharmacists on the distribution per population and per area of inhabitable land.

Methods
Data from 2008 to 2018 were used. Equity among municipalities in the number of community pharmacists per population and per area of inhabitable land was assessed using the Gini coefficient. A mosaic plot was used to demonstrate the relationship between the population density and increase in the number of community pharmacists per municipality.

Results
The number of community pharmacists increased by approximately 1.3-fold from 2008 to 2018 in Japan. The Gini coefficient per population decreased gradually, whereas that per area increased slightly, with no change in distribution per area of inhabitable land. The number of community pharmacists per population increased regardless of the population density, but this increase per area was smaller for lower population density groups and larger for higher population density groups.

Conclusion
The increase in the number of community pharmacists has improved the distribution of community pharmacists per population, but not that per area of inhabitable land. The maldistribution of community pharmacists per area implies an imbalance in the distance between pharmacies and residents. Thus, there is need for measures to improve the distribution of community pharmacists.
Forecasting tectonic tremor activity using a renewal process model
Authors: Ide Satoshi , Nomura Shunichi 
Published: December 2022

AbstractIn many tectonically active regions of the world, a variety of slow deformation phenomena have been discovered and collectively termed slow earthquakes. Tectonic tremor is the high-frequency component of slow earthquakes and can be analyzed to monitor the overall slow deformation process, both spatially and temporally. Although tectonic tremor activity is complex, it does possess some characteristic patterns, such as spatial segmentation, a quasi-periodic recurrence, migration, and tidal modulation. These features are helpful for forecasting future activity if they are properly modeled in a quantitative manner. Here, we propose a stochastic renewal process to standardize and forecast tectonic tremor activity in the Nankai subduction zone, southwest Japan, using a 12.5-year tremor catalog that is divided into a 10-year estimation period and 2.5-year forecasting period. We group the tremor events into small rectangular 10-km regions and observe that the distribution of inter-event times is nearly bimodal, with the short and long inter-event times representing the characteristic times of nearby tremor interactions and long-term stress accumulation processes, respectively. Therefore, as the probabilistic distribution for the renewal process, we adopt a mixture distribution of log-normal and Brownian passage time distributions for the short and long inter-event times, respectively. The model parameters are successfully estimated for 72% of the entire tremor zone using a maximum likelihood method. This standard model can be used to extract anomalous tremor activity, such as that associated with long-term slow-slip events. We derive a scaling relationship between two characteristic times, the relative plate motion, episodicity of tremor activity, and tremor duration by characterizing the spatial differences in tremor activity. We confirm that the model can forecast the occurrence of the next tremor event at a given reference time for a certain prediction interval. This study can serve as a first step for implementing more complex models to improve the space–time forecasting of slow earthquakes.
Digital health interventions to improve eating behaviour of people with a lower socioeconomic position: a scoping review of behaviour change techniques
Authors: Ronteltap Amber , Bukman Andrea J. , Nagelhout Gera E. , Hermans Roel C. J. , Hosper Karen , Haveman-Nies Annemien , Lupker Remko , Bolman Catherine A. W. 
Published: December 2022

AbstractSpecific approaches are needed to reach and support people with a lower socioeconomic position (SEP) to achieve healthier eating behaviours. There is a growing body of evidence suggesting that digital health tools exhibit potential to address these needs because of its specific features that enable application of various behaviour change techniques (BCTs). The aim of this scoping review is to identify the BCTs that are used in diet-related digital interventions targeted at people with a low SEP, and which of these BCTs coincide with improved eating behaviour. The systematic search was performed in 3 databases, using terms related to e/m-health, diet quality and socioeconomic position. A total of 17 full text papers were included. The average number of BCTs per intervention was 6.9 (ranged 3–15). BCTs from the cluster ‘Goals and planning’ were applied most often (25x), followed by the clusters ‘Shaping knowledge’ (18x) and ‘Natural consequences’ (18x). Other frequently applied BCT clusters were ‘Feedback and monitoring’(15x) and ‘Comparison of behaviour’ (13x). Whereas some BCTs were frequently applied, such as goal setting, others were rarely used, such as social support. Most studies (n = 13) observed a positive effect of the intervention on eating behaviour (e.g. having breakfast) in the low SEP group, but this was not clearly associated with the number or type of applied BCTs. In conclusion, more intervention studies focused on people with a low SEP are needed to draw firm conclusions as to which BCTs are effective in improving their diet quality. Also, further research should investigate combinations of BCTs, the intervention design and context, and the use of multicomponent approaches. We encourage intervention developers and researchers to describe interventions more thoroughly, following the systematics of a behaviour change taxonomy, and to select BCTs knowingly.
Mutually exclusive disorder-dependent hearing discomfort in first-episode psychosis and panic disorder: two experiments using the same auditory stimulus set and two similar musical sequences
Authors: de Bustamante Simas Maria Lúcia , da Silva Tamires Lima , dos Santos Naianna Ribeiro Mocelin , Lacerda Aline Mendes 
Published: December 2022

Abstract
We investigated the level of hearing tolerance in patients with first-episode psychosis (FEP) and panic disorder (PD) as compared to two different groups of healthy controls (HC, HC2), one for each experiment, because we used two distinct psychophysical paradigms. We evaluated auditory discomfort of 28 volunteers (14 with FEP and 14 HC) in the first study and of 42 volunteers (21 with PD and 21 HC2) in the second study. We presented 20 sounds: 16 pure-tone frequency sweeps (specially designed for use with FEP) and 11 s or 13 s musical sequences from the very beginning of the music “Play the Game” (PLAY) from Queen and its reverses. The first procedure used a Likert-like 0–10 scale ranging from “nothing bad” to “too bad” where volunteers made vertical marks along a horizontal line according to their discomfort. The second procedure involved subjective magnitude estimation online due to the SARS-COV-19 pandemic. Sounds were placed online and played by PD and HC2 volunteers themselves after having listened to the standard (the first 8 s from RADIO, “Radio Ga Ga” by Queen). Then, PD and HC2 volunteers were asked to assign values equal to, or multiples of 10 that felt like, or proportional to, their hearing “discomfort” in comparison with Sound 00 (RADIO). Our findings showed that FEP volunteers assign more discomfort to the 16 specially designed frequency sweep stimuli that appear not to affect HC, HC2, and PD. On the other hand, musical sequences from PLAY caused strong discomfort to PD in the reverse mode, but did not seem to affect HC, HC2, and FEP. Further experiments using the exact same paradigm with FEP and PD are needed to explore these findings.
The impact of childhood sexual abuse and its associated stigma on depressed women in Egypt
Authors: Sehlo Mohammad Gamal , Youssef Usama Mahmoud , Elgohary Hayam Mohamed , Salah El-deen Ghada Mohamed , Ali Eman Ahmed 
Published: December 2022

Abstract
Background
Depression is common in women, childhood sexual abuse and its related stigma in our culture are expected to increase the severity of depression, and it may be a strong risk factor for the presence of suicidal ideations in women. This study aimed to look at the relationship of childhood history of sexual abuse and its related stigma to depression and suicidal ideations in depressed women.

Methods
A consecutive sample of 160 depressed women was enrolled in this study. The structured clinical interview for DSM-5 was used to diagnose depression, and the Beck Depression Inventory, second edition was used to quantify its severity. The Scale for Suicidal Ideations was used to evaluate suicidal ideations, and history taking was used to assess previous suicidal attempts. The history of childhood sexual abuse was evaluated using a self-report questionnaire, the questions of this questionnaire were derived from the National Population Survey, and a Canadian survey of sexual abuse and its related stigma was assessed using a scale for stigma of sexual abuse.

Results
The findings showed that 11.8% of depressed women had a history of childhood sexual abuse under age of 15 years. There was a significant decrease in age of onset of depression, a significant increase in duration of depression, number of hospital admission, the Beck Depression Inventory, second edition BDI-II, the Beck Hopelessness Scale (BHS) mean scores, number of patients with suicidal ideations, and previous suicidal attempts in depressed women with a history of childhood sexual abuse in comparison to those without that history. History of childhood sexual abuse and its related stigma were the most significant predictors for the presence of depression and current suicidal ideations.

Conclusions
The history of sexual abuse in childhood and its related stigma were associated with increased severity of depression and the presence of suicidal ideations in depressed women. Identification of childhood sexual abuse and its related stigma in depressed women is highly important for proper management of depression.
Achieving midvault symmetry in unilateral cleft nose deformity rhinoplasty
Authors: Baser Brajendra , Singh Pallavi , Shubha Pragati 
Published: December 2022

Abstract
Background
The objective of the study was to provide aesthetic improvement in unilateral cleft nose deformity by reconstructing the midvault of cleft side alone with unilateral osteotomies, simulating symmetry with the normal side, together with tip reconstruction. While most of the literature emphasizes on tip reconstruction, few of them focus on techniques of repositioning the slanting nasal sidewall, which aids in achieving the desired symmetry. We describe a method of repositioning the bony nasal vault to a more lateral and symmetrical orientation by making unilateral osteotomies.

Results
Eighteen patients of unilateral cleft nose deformity underwent rhinoplasty between March 16 and January 20. All patients had prior primary cleft lip repair. Thirteen patients underwent primary rhinoplasty while 5 underwent secondary rhinoplasty having undergone primary rhinoplasty elsewhere. Follow-up was from 1 to 3 years. Results were evaluated using Rhinoplasty Outcome Evaluation [ROE] Questionnaire, and Asher McDade Aesthetic Index [AMAI] Rating. Pre- and post-operative scores were compared.
All patients were subjectively satisfied. The ROE and AMAI scores showed statistically significant improvement from pre-operative scores.

Conclusion
Obtaining symmetry in cleft nose deformity is a surgical challenge even in experienced hands. Using structural grafts only on the cleft side we attempted to create a near normal symmetry and achieve a natural nasal appearance, with satisfactory improvement from both patient’s and surgeons’ perspective.

Level of evidence
Case series- 4