bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stochastic framework for carbon price risk estimation of real estate: a Markov switching GARCH simulation approach
Authors: Oertel Cay , Kovaleva Ekaterina , Gleißner Werner , Bienert Sven 
Published: February 2022

PurposeThe risk management of transitory risk for real assets has gained large interest especially in the past 10 years among researchers as well as market participants. In addition, the recent regulatory tightening in the EU urges financial market participants to disclose sustainability-related financial risk, without providing any methodological guidance. The purpose of the study is the identification and explanation of the methodological limitations in the field of transitory risk modeling and the logic step to advance toward a stochastic approach.Design/methodology/approachThe study reviews the literature on deterministic risk modeling of transitory risk exposure for real estate highlighting the heavy methodological limitations. Based on this, the necessity to model transitory risk stochastically is described. In order to illustrate the stochastic risk modeling of transitory risk, the empirical study uses a Markov Switching Generalized Autoregressive Conditional Heteroskedasticity model to quantify the carbon price risk exposure of real assets.FindingsThe authors find academic as well as regulatory urgency to model sustainability risk stochastically from a conceptual point of view. The own empirical results show the superior goodness of fit of the multiregime Markov Switching Generalized Autoregressive Conditional Heteroskedasticity in comparison to their single regime peer. Lastly, carbon price risk simulations show the increasing exposure across time.Practical implicationsThe practical implication is the motivation of the stochastic modeling of sustainability-related risk factors for real assets to improve the quality of applied risk management for institutional investment managers.Originality/valueThe present study extends the existing literature on sustainability risk for real estate essentially by connecting the transitory risk management of real estate and stochastic risk modeling.
Ambiguity-incorporated opinion formation model for multi-risk large-group emergency decision-making in social networks
Authors: Cao Jing , Xu Xuanhua , Pan Bin 
Published: February 2022

PurposeVarious decision opinions comprise the foundation of emergency decision-making. However, decision-makers have difficulty establishing trust relationships within a short time because of decision-making groups being temporary. The paper aims to develop an ambiguity-incorporated opinion formation model that considers ambiguous opinions on relevant risks from a psychological perspective during the consensus reaching process.Design/methodology/approachAddressing the problem of forming a consensus decision-making opinion in an ambiguous environment and relevant risk opinions, different social network structures were first proposed. Subsequently, psychological factors affecting the decision-makers' perception of ambiguous opinions and tolerance for ambiguity under the multi-risk factors were considered. Accordingly, an ambiguity-incorporated opinion formation model was proposed by considering the ambiguity and relevant opinions on multi-risk factors.FindingsA comparison between the ambiguity-incorporated opinion formation model and the F–J model illustrates the superiority of the proposed model. By applying the two types of network structures in the simulation process, the results indicate that the convergence of opinions will be affected by different decision-making network structures.Originality/valueThe research provides a novel opinion formation model incorporating psychological factors and relevant opinions in the emergency decision-making process and provides decision support for practitioners to quantify the influence of ambiguous opinions. The research allows the practitioners to be aware of the influence of different social network structures on opinion formation and avoid inaccurate opinion formation due to unreasonable grouping in emergency decision-making.
Corporate social responsibility in post COVID-19 period: critical modeling and analysis using DEMATEL method
Authors: Chatterjee Sheshadri , Chaudhuri Ranjan , Vrontis Demetris , Thrassou Alkis 
Published: February 2022

PurposeThe purpose of this study is to identify the critical success factors (CSFs) of corporate social responsibility (CSR) in the post-COVID-19 period and to identify the cause–effect relationships amongst those CSFs.Design/methodology/approachThe success factors impacting CSR activities are identified based on inputs from 14 experts in the CSR domain. Thereafter, authors use a statistical approach to identify CSFs with inputs from useable respondents. Finally, the Decision-Making Trial and Evaluation Laboratory (DEMATEL) method was applied to understand the causal relationship between different CSFs.FindingsUsing the DEMATEL method, the authors developed an analytical model showing cause–effect aspects of the CSFs and identified seven factors which firms need to emphasize more to execute better CSR activities in the post-COVID-19 period.Research limitations/implicationsThe authors asked 14 experts for their inputs, but more experts could have made identifying success factors more comprehensive. In this study, the DEMATEL method found seven CSFs that improve CSR activities in the post-COVID-19 period. Another identification process could have enriched the study. The findings of this study cannot be generalized since this study is based on the inputs of employees from India only.Practical implicationsThis proposed analytical model is effective in determining the complex interactions among all impacting CSFs. Firms' CSR managers and policy makers can use the proposed model, especially in the post-COVID-19 period.Originality/valueThe proposed model provides a precise and most accurate analysis for CSFs impacting CSR activities in the post-COVID-19 period. It also provides a unique opportunity for the competent authorities at firms to understand the interaction of different impacting CSFs and takes necessary actions. No other exhaustive analytical model is available in this context.
Nano-dispersible azo pigments from lignin: a new synthetic approach and epoxy-polyamine composite coating
Authors: Patil Rahul , Jadhav Lina , Borane Nikhil , Mishra Satyendra , Patil Vikas 
Published: February 2022

Purpose
Here, diazo coupling reaction was imparted on chemically inert lignin isolated from natural resources. Activated lignin was coupled with the diazotised aniline, m-nitroaniline, p-nitroaniline-, and p-anisidine gives organic pigments.

Design/methodology/approach
The continuous increase in particle size of pigments confirms addition of diazotised salt to lignin by coupling reaction. Further, the dispersing ability of these coloured pigments were exploited in polymer matrix. Epoxy-polyamine cross linking system was doped with difference percentage of pigments and coated on mild steel metal surface. The morphology of these composites was understood by SEM, particle size, differential scanning calorimeter and thermo gravimetric analysis.

Findings
The synthesised organic pigments were characterised by FT-IR, 1H NMR and UV-visible spectroscopy. It was observed that hiding power of aniline- and m-nitroaniline–based azo pigments was more than p-nitroaniline- and p-anisidine–based azo pigments. Thermal properties as well as water contact angles of coatings were improved with pigment concentration. The chemical resistivity of coating was observed to be improved with the increasing % of lignin-based azo pigment.

Originality/value
Lignin-based azo pigment has great potential to replace metal oxide pigment and provide strategy for utilisation of lingo-cellulosic biowaste material.
Management control systems and the strategic management of innovation
Authors: Biswas Sharlene Sheetal Narayan , Akroyd Chris 
Published: February 2022

PurposeThis paper aims to understand the strategic management of innovation by examining the effect that management control systems (MCS) have on innovation activities during the strategic change process.Design/methodology/approachA case study was carried out at an innovative company as they undertook a strategic change from closed innovation to open innovation. Simons’ levers of control was used to frame the ways in which MCS were designed and used by managers and the effect MCS have on the innovation activities of organization members.FindingsThe findings indicate that while managers designed and used MCS to support a drive toward open innovation, organization members did not change their innovation activities. Instead, the findings show that new MCS enabled improvements to their closed innovation strategy. This led to a decrease in the time taken to develop new products, which resulted in increased customer satisfaction, which contributed to the achievement of organizational goals.Originality/valueBy focusing on the relationship between MCS and innovation activities in the strategic change process, the paper sheds new light on the ability of MCS to change the innovation activities of organization members. Even though the innovation activities at our case company did not change the interactions between the MCS enabled organizational goals to be achieved as they provided the necessary information infrastructure and motivated goal congruence.
University students’ experiences of recreational class a drug taking and perspectives on personal, social and health education (PSHE) drug education
Authors: Scott Hannah May , Oliver Sandy 
Published: February 2022

Purpose
Research suggests that student drug use is substantially higher than that of the general population and while the UK Government’s current Drug Strategy emphasises the importance of PSHE in preventing young people from becoming drug users, there is a lack of research investigating the longer-term effectiveness of drug prevention education, and students’ views using qualitative methods. The purpose of this paper is to gain a holistic understanding into university students’ lived experiences of recreational class A drug taking and the drug education taught in English secondary schools.

Design/methodology/approach
Five interviews with university students were undertaken and thematically analysed using an ideographic case study approach alongside a qualitative content analysis of publicly available drug education resources and policy documents.

Findings
The normalisation of drug taking at university and social micro-pressures to assimilate group norms were key contributing factors to participants’ drug use. While the content of drug education in PSHE is grounded in theory, its implementation is not.

Originality/value
This study extends upon existing theories of normalisation of drug use at university through the concept of micro-pressures to offer an explanation of the process by which students assimilate group norms through the implicit threat of not fitting in.
Supervisor support, career satisfaction, and career adaptability of healthcare sector employees
Authors: Tahiry Mohammad Aqil , Ekmekcioglu Emre Burak 
Published: February 2022

Purpose
The purpose of this study is to examine the mediating role of career adaptability (CA) in the relationship between supervisor support (SS) and career satisfaction (CS).

Design/methodology/approach
Data were collected from 193 full-time employees working in private health-care institutions in Ankara, Turkey. The participants were asked to respond to a self-reported survey. Structural equation modeling was used to examine the hypothesized relationships between the research variables.

Findings
The results indicated that SS has a significant and positive effect on CS. It further reveals that CA mediates the effect of SS on CS.

Research limitations/implications
As this study had a cross-sectional research design, causality could not be established between study variables.

Practical implications
CA ought to be considered by the managers and it ought to be advanced as it provides the employees fundamental instruments to deal with their career advancement efficiently.

Originality/value
The present study adds to the existing literature by providing additional evidence for the relationship among SS, CA and CS by examining a sample of health-care professionals.
Dual‐target synergistic antithrombotic mechanism of a dabigatran etexilate analogue (HY023016)
Authors: Wan Sheng , Cui Shuang , Jiang Minrui , Wu Qian , Ji Yingying , Xu Yungen , Gong Guoqing 
Published: February 2022

AbstractThrombin has long been considered a desirable antithrombotic target, but anti‐thrombin therapy without anti‐platelet therapy has never achieved the ideal effect. HY023016, derived from dabigatran etexilate, exhibited a potent antithrombotic efficacy. In the present study, mechanisms underlying this effect were explored. HY023016 strongly decreased the binding of thrombin to recombinant GPIbα N‐terminal sequence, which was confirmed by surface plasmon resonance. Flow cytometry revealed that HY023016 selectively decreased the binding of antibody to GPIbα and inhibited the washed human platelet aggregation induced by thrombin. Fluorescence experiment showed that HY023016 remarkably inhibited exosite II by a loss of affinity for the γ'‐peptide of fibrinogen. Using intravital microscopy, we observed and recorded the dynamic process of thrombus formation and found that HY023016 effectively prevented thrombus formation in rat arteriovenous shunt thrombosis model. On the basis of these findings, we propose that HY023016 provides a novel insight into the antithrombotic mechanism, which exerts synergistic anticoagulant and antiplatelet effects through thrombin and GPIbα.
Identification and expression profiles of gustatory receptor genes in Bactrocera minax larvae (Diptera: Tephritidae): Role of BminGR59f in larval growth
Authors: Zhang Guijian , Cao Shuai , Guo Tong , Wang Haoran , Qi Xuewei , Ren Xueming , Niu Changying 
Published: February 2022

AbstractInsects employ various types of gustatory receptors (GRs) to identify nutrient‐rich food and avoid toxic substances. The larval gustatory system is the critical checkpoint for food acceptance or rejection. As a specialist herbivore, the larvae of Bactrocera minax feed only on unripe citrus fruits. However, how larvae use GRs to check and adapt to the secondary metabolites in unripe citrus fruits remains unknown. In this study, we first performed developmental expression profiles showing that most BminGRs genes were highly expressed in 1st and 2nd instar larvae and that tissue‐specific expression indicated high expression of most BminGRs genes in the mouthparts of 2nd instar larvae. Furthermore, we found that silencing BminGR59f by RNA interference (RNAi) affected the growth of 2nd instar B. minax larvae. Hesperidin and naringin were screened as ligands of BminGR59f via RNAi and cell calcium imaging, and the combination of these two flavones increased the body weight of larvae. In summary, we identified a novel gustatory perception pattern in B. minax for detecting hesperidin and naringin, which boosted the growth of B. minax larvae. These results shed light on how specialist herbivores detect and adapt to host metabolites in adverse environments depending on larval GRs.
Acute fulminant hepatitis associated with osimertinib administration in a lung cancer patient with chronic hepatitis B: The first mortality case report
Authors: Kang You‐Kuang , Meng Fan‐Chun 
Published: February 2022

AbstractOsimertinib is the most efficient first‐line drug, with least adverse effects, for metastatic non‐small‐cell lung carcinoma (NSCLC) harboring epidermal growth factor receptor (EGFR) mutations with exon 19 deletion or exon 21 L858R mutations. Herein, we present a 68‐year‐old woman who had chronic hepatitis B with aggressive NSCLC and received osimertinib as cancer treatment for 4.5 months. This is the first report of mortality due to osimertinib‐related acute fulminant hepatitis. Clinicians should routinely arrange for hepatitis B virus (HBV) screening and prescribe antiviral drugs to patients with chronic HBV infection before osimertinib administration.
Sociodemographic differences in youth alcohol sipping's nomological network
Authors: Watts Ashley L. , Megahan JaiAnna F. , Conlin William E. , Doss Mark I. , Sher Kenneth J. 
Published: February 2022

AbstractBackgroundPrevious research has established that certain features of personality (e.g., impulsivity), psychopathology (e.g., impulsivity, mood disorder, thought disorder), and contextual factors (e.g., parenting, parental alcohol use) are associated with an increased likelihood of having sipped alcohol in youth, and substance involvement and problems in adolescence and adulthood. What is less clear from the existing literature is whether well‐established risk factors of substance use are consistent across sociodemographic characteristics (i.e., gender, race/ethnicity, religious affiliation, income, parental education).MethodsWe used a large, community sample of 9‐ and 10‐year‐olds (N = 11,872; 53% female) to examine whether various sociodemographic characteristics moderate the associations between sipping behavior and its various well‐established correlates (e.g., impulsivity, behavioral inhibition and activation, psychopathology, parenting, and family conflict).ResultsThere were small mean level differences in sipping across sociodemographic characteristics. Across sociodemographic characteristics, however, sipping was fairly uniformly associated with youth‐reported impulsivity, behavioral activation, prodromal psychosis symptoms, mood and externalizing disorder diagnoses, family environment, and parental alcohol consumption indices. Effects were sometimes slightly more pronounced among groups for which alcohol consumption is relatively nonnormative: Sipping among female youth was slightly more associated with thought disorder psychopathology than among male youth (D = 0.07), and was slightly more associated with some aspects of psychopathology and impulsivity for Black youth than White and Hispanic youth (Ds were 0.07 and 0.09).ConclusionsBroadly, our findings suggest that the psychosocial correlates of precocious alcohol use are relatively consistent across sociodemographic factors.
Interferon epsilon and preterm birth subtypes; a new piece of the type I interferon puzzle during pregnancy?
Authors: Taylor Brandie DePaoli , Criscitiello Michael F. , Hernandez Tyne , Norwood Brooke , Noah Akaninyene I. , Bazer Fuller W. 
Published: February 2022

AbstractProblemInterferon epsilon (IFNε) is a unique type I IFN that is expressed in response to sex steroids. Studies suggest that type I IFNs regulate inflammation‐induced preterm birth (PTB), but no study has examined the role of IFNε in human pregnancy.Method of StudyWe used stored vaginal swabs between 8 and 26 weeks of gestation from the Global Alliance to Prevent Prematurity and Stillbirth (GAPPS) biobank and measured IFNε by enzyme‐linked immunosorbent assay (ELISA). A total of 29 women with spontaneous preterm births, 34 women with medically indicated preterm births, and 134 women with term births were included. Secondary outcomes included a preterm birth with chorioamnionitis and preeclampsia with a preterm birth. Logistic regression calculated odds ratios (OR) and 95% confidence intervals (CI) adjusting for maternal age, race, body mass index, prior pregnancy complications, lower genital tract infections, chronic health conditions, and gestational age at blood draw.Results and ConclusionsThere was no significant association between IFNε and spontaneous preterm birth (ORadj 1.0, 0.8–1.3) or chorioamnionitis (ORadj 1.6, 0.7–3.5). A trend toward increased odds of medically indicated preterm birth (ORadj. 1.3, 1.0–1.8) was observed. This was likely due to elevated IFNε among women with preterm preeclampsia (ORadj. 2.0, 95% CI 1.3–3.2). While exploratory, our novel findings suggest that larger longitudinal studies of IFNε across human pregnancy may be warranted.
Policy Networks Across Political Systems
Authors: Metz Florence , Brandenberger Laurence 
Published: February 2022

AbstractPolities shape power structures and interaction patterns between actors in policymaking processes. Although the social fabric of interactions is key to successful policymaking, it remains unclear which relational structures are typically found across political systems. By adopting a network approach, we analyse differences in power structures and interaction patterns across four policy networks in German and Swiss consensual–federal, French majoritarian–unitary, and hybrid Dutch consensual–unitary democracies. Using survey data from 149 state and non‐state actors, we fit exponential random graph models and calculate predicted probabilities to compare the four networks. Results show that the consensus democracies institutionalize neighbourhoods of networks where actors share power and collaborate with opponents. Our case of a majoritarian democracy illustrates power concentration with restricted access to competitors, limiting the need to interact and search for compromises with opponents. Findings allow future work to differentiate typical from atypical network structures, given the embeddedness into a political system.
COVID‐19 vaccination in patients receiving allergen immunotherapy (AIT) or biologicals—EAACI recommendations
Authors: Jutel Marek , Torres Maria J. , Palomares Oscar , Akdis Cezmi A. , Eiwegger Thomas , Untersmayr Eva , Barber Domingo , Zemelka‐Wiacek Magdalena , Kosowska Anna , Palmer Elizabeth , Vieths Stefan , Mahler Vera , Canonica Walter G. , Nadeau Kari , Shamji Mohamed H , Agache Ioana 
Published: February 2022

AbstractImmune modulation is a key therapeutic approach for allergic diseases, asthma and autoimmunity. It can be achieved in an antigen‐specific manner via allergen immunotherapy (AIT) or in an endotype‐driven approach using biologicals that target the major pathways of the type 2 (T2) immune response: immunoglobulin (Ig)E, interleukin (IL)‐5 and IL‐4/IL‐13 or non‐type 2 response: anti‐cytokine antibodies and B‐cell depletion via anti‐CD20. Coronavirus disease 2019 (COVID‐19) vaccination provides an excellent opportunity to tackle the global pandemics and is currently being applied in an accelerated rhythm worldwide. The vaccine exerts its effects through immune modulation, induces and amplifies the response against the severe acute respiratory syndrome coronavirus (SARS‐CoV‐2). Thus, as there may be a discernible interference between these treatment modalities, recommendations on how they should be applied in sequence are expected.The European Academy of Allergy and Clinical Immunology (EAACI) assembled an expert panel under its Research and Outreach Committee (ROC). This expert panel evaluated the evidence and have formulated recommendations on the administration of COVID‐19 vaccine in patients with allergic diseases and asthma receiving AIT or biologicals. The panel also formulated recommendations for COVID‐19 vaccine in association with biologicals targeting the type 1 or type 3 immune response. In formulating recommendations, the panel evaluated the mechanisms of COVID‐19 infection, of COVID‐19 vaccine, of AIT and of biologicals and considered the data published for other anti‐infectious vaccines administered concurrently with AIT or biologicals.