bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pancreas-preserving partial duodenectomy for non-ampullary duodenal neoplasms: three case reports
Authors: Ishida Shunsuke , Hirashita Teijiro , Kawano Yoko , Orimoto Hiroki , Amano Shota , Kawamura Masahiro , Fujinaga Atsuro , Kawasaki Takahide , Masuda Takashi , Endo Yuichi , Ohta Masayuki , Inomata Masafumi 
Published: July 2022

Abstract
Background
There are multiple surgical procedures for resecting non-ampullary duodenal neoplasms (NADNs), and the appropriate method is selected depending on the tumor location and diagnosis. We herein report 3 cases of NADNs that were resected using pancreas-preserving partial duodenectomy (PPD).

Case reports
The first patient, a 73-year-old woman with a circumferential duodenal adenoma in the supra-ampullary duodenum, underwent surgery. After laparotomy, the duodenum proximal to the tumor was confirmed using intraoperative endoscopy and dissected. The duodenum distal to the tumor was dissected under direct visualization, and the specimen was removed. The distal stump of the duodenum was closed, and duodenojejunostomy was performed as described by Billroth II. The tumor was diagnosed as an adenoma 75 mm in size. She was discharged 12 days after surgery without any complications. The second patient, a 48-year-old man, was diagnosed with a neuroendocrine neoplasm (NEN) with a diameter of 14 mm in the supra-ampullary duodenum. Laparoscopic PPD was performed. He was diagnosed with NEN G1 and discharged the 11th day after surgery. The third patient, a 71-year-old man with a 0–Is + IIa lesion in the horizontal duodenum, underwent surgery. After laparotomy, the horizontal duodenum and proximal jejunum were resected, and duodenojejunostomy was performed. The patient was diagnosed with stage I adenocarcinoma and discharged on the 15th day after surgery.

Conclusion
PPD is useful for avoiding the morbidity of pancreatoduodenectomy in the management of NADNs without invasion to the ampulla of Vater or pancreas.
Landscape scale ecology of Tetracladium spp. fungal root endophytes
Authors: Lazar Anna , Mushinski Ryan M. , Bending Gary D. 
Published: July 2022

Abstract
Background
The genus Tetracladium De Wild. (Ascomycota) has been traditionally regarded as a group of Ingoldian fungi or aquatic hyphomycetes—a polyphyletic group of phylogenetically diverse fungi which grow on decaying leaves and plant litter in streams. Recent sequencing evidence has shown that Tetracladium spp. may also exist as root endophytes in terrestrial environments, and furthermore may have beneficial effects on the health and growth of their host. However, the diversity of Tetracladium spp. communities in terrestrial systems and the factors which shape their distribution are largely unknown.

Results
Using a fungal community internal transcribed spacer amplicon dataset from 37 UK Brassica napus fields we found that soils contained diverse Tetracladium spp., most of which represent previously uncharacterised clades. The two most abundant operational taxonomic units (OTUs), related to previously described aquatic T. furcatum and T. maxilliforme, were enriched in roots relative to bulk and rhizosphere soil. For both taxa, relative abundance in roots, but not rhizosphere or bulk soil was correlated with B. napus yield. The relative abundance of T. furcatum and T. maxilliforme OTUs across compartments showed very similar responses with respect to agricultural management practices and soil characteristics. The factors shaping the relative abundance of OTUs homologous to T. furcatum and T. maxilliforme OTUs in roots were assessed using linear regression and structural equation modelling. Relative abundance of T. maxilliforme and T. furcatum in roots increased with pH, concentrations of phosphorus, and increased rotation frequency of oilseed rape. It decreased with increased soil water content, concentrations of extractable phosphorus, chromium, and iron.

Conclusions
The genus Tetracladium as a root colonising endophyte is a diverse and widely distributed part of the oilseed rape microbiome that positively correlates to crop yield. The main drivers of its community composition are crop management practices and soil nutrients.
Two cases of catheters inserted from the femoral vein straying into the hepatic vein, possibly owing to a Eustachian valve: a case report
Authors: Takise Yoshiaki , Maeda Takuma , Yonezawa Hiroki , Minami Kimito , Morinaga Masahiro , Ohnishi Yoshihiko 
Published: July 2022

Abstract
Background
In minimally invasive cardiac surgery (MICS) and extracorporeal membrane oxygenation (ECMO), a guidewire is inserted from the femoral vein (FV) into the right atrium. However, rarely, the guidewire or catheter strays into the hepatic vein (HV) because of the inferior vena cava (IVC)-HV angle. We report two cases in which a guidewire and venous cannula from the FV strayed into the HV, likely owing to a Eustachian valve.

Case presentation
Both patients were women who underwent transesophageal echocardiography-guided FV cannulation. In case 1, a guidewire from the FV strayed into the HV owing to a Eustachian valve. In case 2, ECMO was established postoperatively. Transthoracic echocardiography confirmed the venous cannula had strayed into the HV. Computed tomography indicated IVC-HC angles of 129° (case 1) and 102° (case 2).

Conclusion
A Eustachian valve can impede devices inserted from the FV and even allow them to stray into the HV.
Does health economics research align with the disease burden in the Middle East and North Africa region? A systematic review of economic evaluation studies on public health interventions
Authors: Nagi Mouaddh Abdulmalik , Rezq Mustafa Ali Ali , Sangroongruangsri Sermsiri , Thavorncharoensap Montarat , Dewi Pramitha Esha Nirmala 
Published: July 2022

Abstract
Introduction
Economic evaluation studies demonstrate the value of money in health interventions and enhance the efficiency of the healthcare system. Therefore, this study reviews published economic evaluation studies of public health interventions from 26 Middle East and North Africa (MENA) countries and examines whether they addressed the region's major health problems.

Methods
PubMed and Scopus were utilized to search for relevant articles published up to June 26, 2021. The reviewers independently selected studies, extracted data, and assessed the quality of studies using the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) checklist.

Results
The search identified 61 studies. Approximately half (28 studies; 46%) were conducted in Israel and Iran. The main areas of interest for economic evaluation studies were infectious diseases (21 studies; 34%), cancers (13 studies; 21%), and genetic disorders (nine studies; 15%). Five (8%), 39 (64%), 16 (26%), and one (2%) studies were classified as excellent, high, average, and poor quality, respectively. The mean of CHEERS checklist items reported was 80.8% (SD 14%). Reporting the structure and justification of the selected model was missed in 21 studies (37%), while price and conversion rates and the analytical methods were missed in 21 studies (34%).

Conclusions
The quantity of economic evaluation studies on public health interventions in the MENA region remains low; however, the overall quality is high to excellent. There were obvious geographic gaps across countries regarding the number and quality of studies and gaps within countries concerning disease prioritization. The observed research output, however, did not reflect current and upcoming disease burden and risk factors trends in the MENA region.
Influence of knowledge, attitudes, and behaviors of added sugars consumption on periodontal status in low-income women
Authors: Babaei Mahsa , Freeland-Graves Jeanne , Sachdev Prageet K. , Wright Gary J. 
Published: July 2022

Abstract
Background
Periodontitis is a chronic inflammatory disease caused by interactions between bacterial infection and host response. Nutrition education plays an important role in preventing oral health diseases and related problems. The present research will assess oral hygiene practices, nutrition knowledge, attitudes, and behaviors related to added sugars, within the context of periodontal disease in low-income women.

Methods
A pre-validated Dental Nutrition Attitudes, Beliefs, and Behaviors questionnaire was distributed among 220 low-income women. Periodontal disease was measured using clinical attachment loss and probing pocket depth. One-way ANOVA, linear, and multivariate logistic regression were utilized for analysis.

Results
Linear regression analysis exhibited significant positive associations of knowledge with attitude (r = 0.190, P = 0.000), and behavior (r = 0.298, P = 0.000), as well as attitude with behavior (r = 0.542, P = 0.000) of the low-income women. Women who scored higher on knowledge subscale were less likely to be in stage 2 [OR = 0.21, 95% CI: 0.008–0.582, P = 0.002] and 3 [OR = 0.32, 95% CI: 0.009–0.916, P = 0.021], as compared to the lower stage. Those who scored higher on the attitude and behavior subscales were less likely to be in stage 2 [OR = 0.191, 95% CI: 0.066-.0559, P = 0.003 vs OR = 0.501, 95% CI: 0.172–1.461, P = 0.046] and 3 [OR = 0.178, 95% CI: 0.051–0.620, P = 0.007 vs OR = 0.215, 95% CI: 0.062–0.744, P = 0.015] than in stage 1.

Conclusions
Significant limited dental nutrition attitude, belief, and behavior regarding periodontal disease were observed. Health care professionals and dentists should provide nutrition counseling about periodontal disease during health care delivery visits.
Ethnobotanical survey of herbs used in the preservation of food products in Fez, Morocco
Authors: Ez zoubi Yassine , Lairini Sanae , El Amrani Soukaina , El-Akhal Fouad , Farah Abdellah , Bouslamti Rabia , El Ouali Lalami Abdelhakim 
Published: July 2022

AbstractMorocco has a rich plant biodiversity and an ancient ethnobotanical knowledge influenced by the ethnic diversity of the Moroccan population. This heritage has been preserved from generation to generation by traditional herbalists. In this study, data were collected via a survey of herbalists based on the direct interview technique. Questions addressed the herbalists’ age and education level as well as the vernacular names and parts of the plants used for the preservation of food. The species use value was used to identify the most important species recommended by herbalists. The average age of the participants was 52.55 years, and the illiteracy rate was 46%. A total of 32 plant species representing 16 families were identified as being used in the preservation of various food products. The most important family was Lamiaceae, followed by Apiaceae and Rosaceae. The most frequently used parts of the plant were the leaves (26.37%), followed by the fruit (24.7%), and the whole plant (12.7%). The highest use values were recorded for Citrus limon (0.16), Thymus vulgaris (0.14), Rosmarinus officinalis (0.12), Artemisia herba alba (0.11) and Lavandula dentata (0.1). Meat, vegetables and fish were the most commonly preserved food products. This ethnobotanical survey on the preservation of food products is the first of its kind conducted in Morocco and has implications for meeting consumer demands and understanding the potential uses of plants in the preservation of food products.
Middle-East obgyn graduate education (MOGGE) foundation practice guidelines: diagnostic approach to pregnancy of unknown location: practice guideline no. 03-O-21
Authors: Shazly Sherif A. , Radwan Ahmad A. , Abdo Mohamed S. , Moustafa Hajer Y. , Abd-Elkariem Ahmed Yassien , Ali Shimaa Salah , Ahmed Nermeen B. , Hosny Esraa M. , Abouzeid Mostafa H. , Eltaweel Nashwa A. , Hortu Ismet , Abdelbadie Amr S. , Fahmy Mohamed S. , Attyia Mohamed I. , Shawki Abdelrahman A. , Said Aliaa E. , Mohamed Yasmin I. , Hemdan Heba N. , Hemdan Menna N. , Mohamed Norhan G. , Adam Rania I. 
Published: July 2022

Abstract
Background
Pregnancy of unknown location (PUL) is a term used to describe failure of visualization of intrauterine or extrauterine gestational sac in a woman with a positive pregnancy test.

Body of the abstract
Ectopic pregnancy (EP) accounts for 1–2 % of all pregnancies. EP contributes to maternal mortality of a known cause by 4% in developed countries. However, case fatality rate may be 10 times higher in low-resource countries. This may be attributed to delayed diagnosis and lack of resources. PUL is a temporary term that may eventually lead to diagnosis of viable intrauterine pregnancy, pregnancy loss, or more seriously, EP.

Conclusion
This guideline appraises current evidence on assessment of PUL and early diagnosis of EP particularly in low-resource settings.
An unusual case of bronchopericardial fistula secondary to necrotizing pneumonia
Authors: Bharti Prachi , Agarwal Vivek , Kuruvilla Jerin , Singla Subhash 
Published: July 2022

Abstract
Background
Pneumopericardium is a rare complication in patients with bacterial necrotizing pneumonia and proven to be lethal with a high incidence of mortality due to cardiopulmonary failure.

Case presentation
This is a rare case of broncho-pericardial fistula in a 21 year old, who was a known case of T-cell acute lymphoblastic leukemia status post-chemotherapy, presented with relapse of acute lymphoblastic leukemia. He was evaluated for febrile neutropenia. Further investigation showed features of necrotizing pneumonia and follow-up chest X-ray during the hospital stay showed evidence of pneumopericardium. To localize the cause, computed tomography chest was performed, further confirming the etiology of bronchopericardial fistula.

Conclusions
Our case illustrates broncho-pericardial fistula as a rare complication of necrotizing pneumonia and the utility of multimodality imaging in its diagnosis and determination of tension pneumopericardium.
Multidisciplinary approach in diagnosis and treatment of COVID-19-associated mucormycosis: a description of current reports
Authors: Gogineni Hyma , So Wonhee , Mata Kenneth , Greene John N. 
Published: July 2022

Abstract
Background
We reviewed the epidemiology, risk factors, pathophysiology, and clinical presentations of coronavirus disease 2019 (COVID-19)-associated mucormycosis (CAM), then discussed the importance of rapid diagnosis and treatment facilitated by multidisciplinary approach.

Main body
India has reported world’s highest number of CAM cases where Rhizopus arrhizus was the most predominant etiology. CAM caused by Rhizopus microsporus was the most common from the rest of the world. Multiple risk factors for CAM were identified including diabetes mellitus, inappropriate corticosteroid use, COVID-19-related hypoxia, and lung damage.
Rhino-orbito-cerebral mucormycosis (ROCM) accounted for almost 90% of CAM in India while 64% of global cases were ROCM. Less than 10% of CAM from India were pulmonary while the rest of the world reported 21% of pulmonary CAM.
CAM is diagnosed by confirmed SARS-CoV2 infection along with clinical, radiological, histopathological, and/or microbiological evidence of mucormycosis. In patients with risks of CAM and associated symptoms, CT or MRI are recommended. If ROCM is suspected, endoscopy and biopsy are recommended. If pulmonary CAM is suspected, tissue biopsies, nasal samples, or bronchoalveolar lavage is recommended with histopathological exams.
Early diagnosis, surgical, and pharmaceutical interventions are key to treat mucormycosis. Upon diagnosis, antifungal therapy with liposomal amphotericin B (IV) is considered first-line of therapy. Alternatively, posaconazole (PO/IV) or isavuconazole (PO/IV) can be used.

Conclusion
Treating CAM requires a multidisciplinary approach for early diagnosis and prompt initiation of interventions to maximize patient’s chance of survival.
Comparative study between single-stage multilevel surgery and staged surgery for management of snoring and/or obstructive sleep apnea
Authors: Gafar Hazem Abdel-Latif , Abdulla Alaa El-Din Ali , Ghanem Youssef Yehia , Bahgat Ahmed Yassin 
Published: July 2022

Abstract
Background
When the nasal obstruction is identified in cases of snoring and/or OSA with suspected oropharyngeal and nasal obstruction, the combination of nasal and palate surgeries is suggested to be conducted in either a single-staged or multi-staged manner. This study aimed to assess the efficacy and safety of combined nasal-palatopharyngeal surgery in a staged versus a single-stage multilevel procedure.

Methods
Prospective randomized comparative study included 60 patients with combined nasal and retropalatal obstruction, > 18 years old, BMI < 40, with snoring and/or mild to moderate OSA (AHI ˂ 30) and ASA < 3. Patients were randomly allocated into three groups (every 20 patients); groups 1 and 2 patients underwent a staged procedure, where group 1 had a nasal surgery as a first step for management of nasal obstruction, followed by a BRP after 3 months and vice versa for group 2 patients, while group 3 patients had a single-stage combined nasal surgery and (BRP). Preoperative and 6 months post-operative SOS, SBPS, ESS scores, and polysomnography data (AHI, ODI) were recorded. Post-operative complications, pain (VAS), and duration of hospital stay were monitored.

Results
Post-operative improvement in SOS, SBPS, EES, AHI, and ODI were similar after a staged or a single-stage multilevel procedure with no significant intergroup differences. Total operative time for single-stage multilevel surgery (80 ± 25 min) was significantly shorter than that for the staged procedure (135 ± 30 min). Post-operative complications were temporary and not severe in both surgical procedures and included wound infection (11.67%) and nasal bleeding (11.67%), which were resolved immediately by firm pressure and nasal packing and suture extrusion (5%). However, it didn't appear to alter anatomical and functional outcomes. Post-operative pain by VAS was significantly higher after a single-stage multilevel procedure (5.8 ± 1.4) compared to (2.8 ± 0.6 and 3.7 ± 0.7, respectively) in groups 1 and 2 that underwent a staged surgery.

Conclusion
Combined nasal surgery and BRP, either staged or single-stage multilevel procedure in the treatment of snoring and/or mild and moderate OSA with nasal obstruction, provide similar successful improvement in subjective and objective findings. A single-stage procedure was safer because of a significantly shorter total operative time, and repeated hospitalization and need for anesthesia were avoided.
Asymptomatic idiopathic submandibular abscess — a diagnostic conundrum
Authors: Agarwal Shreya , Gupta Nimish 
Published: July 2022

Abstract
Background
Facial and neck abscesses are often seen in patients. Usually, they are linked to a primary source of infection in orofacial, dental, or otolaryngeal region and are associated with the classic signs and symptoms of infection and inflammation. We came across a case of submandibular abscess whose behavior pattern defied the typical trends.

Case presentation
A completely asymptomatic boy reported with a huge swelling below the left-side lower jaw, extending onto the neck region. The history of swelling was acute with progressive nature since the last 5–6 days. His clinical examination and the laboratory investigations were quite routine without any deviation from usual. Despite exploring for all probable causes, authors could not find the definitive reason for such unusual presentation.

Conclusion
Although the patient was cured with conventional medical and surgical treatment for head and neck space infection, the pathophysiology of such asymptomatic and idiopathic abscess remained a diagnostic dilemma.
Early detection of cochlear hearing loss in rheumatoid arthritis patients: a cross-sectional study
Authors: Elnagdy Ola H. , Elfarrash Sara , Fawzy Iman M. , Elnagdy Noha H. 
Published: July 2022

Abstract
Background
Rheumatoid arthritis (RA) is an inflammatory autoimmune disorder that has cardinal articular and peri-articular symptoms. Extra-articular manifestations (EAMs) are also reported among RA patients. In the current study, we assessed hearing function in 50 RA patients. An extensive audiological assessment including pure tone audiometry (PTA), extended high-frequency audiometry (EHFA), tympanometry, and acoustic reflex in addition to the oto-acoustic emission (OAEs) were done.

Results
Our data demonstrates that among the 50 participants with median disease duration of 8 years, about 80% had normal hearing using PTA and EHFA. However, 46% of them had—interestingly—demonstrated absent OAEs, suggesting early stages of cochlear hearing loss.

Conclusion
We conclude that rheumatoid arthritis can cause hearing impairment that can be early diagnosed by TEOAEs.
Recent advances in proteomics and metabolomics in plants
Authors: Yan Shijuan , Bhawal Ruchika , Yin Zhibin , Thannhauser Theodore W. , Zhang Sheng 
Published: July 2022

AbstractOver the past decade, systems biology and plant-omics have increasingly become the main stream in plant biology research. New developments in mass spectrometry and bioinformatics tools, and methodological schema to integrate multi-omics data have leveraged recent advances in proteomics and metabolomics. These progresses are driving a rapid evolution in the field of plant research, greatly facilitating our understanding of the mechanistic aspects of plant metabolisms and the interactions of plants with their external environment. Here, we review the recent progresses in MS-based proteomics and metabolomics tools and workflows with a special focus on their applications to plant biology research using several case studies related to mechanistic understanding of stress response, gene/protein function characterization, metabolic and signaling pathways exploration, and natural product discovery. We also present a projection concerning future perspectives in MS-based proteomics and metabolomics development including their applications to and challenges for system biology. This review is intended to provide readers with an overview of how advanced MS technology, and integrated application of proteomics and metabolomics can be used to advance plant system biology research.
Experimental evaluation of a modified direct evaporative cooling system combining luffa fiber—charcoal cooling pad and activated carbon dehumidifying pad
Authors: Ahmadu T. O. , Sanusi Y. S. , Usman F. 
Published: July 2022

AbstractEvaporative cooling technology has a potential to serve as a substitute to conventional vapor compression cooling. Direct evaporative cooling however usually introduces more moisture to the cooling space. In this study, the performance of a modified direct evaporative cooling system that combines a cooling pad and a removable dehumidifying pad has been experimentally evaluated for space cooling. The cooling pad is made of luffa fiber lagged with charcoal, while the dehumidifying pad is made of activated carbon derived from tamarind seed. Results for two experimental days, which span from 8:30 am to 5:30 pm each day are reported in this work. The peak cooling load requirement of the room was evaluated as 4.53 kW. On the first experimental day, in which the dehumidifying pad was removed from the system, results indicated a minimum room temperature of 24oC was achieved, which resulted in a maximum temperature drop of 11oC from ambient temperature. However, indoor relative humidity increased to a maximum of 84%, while outdoor relative humidity was 30%. The dehumidifying pad was used on the second experimental day. Results from the second experimental day showed a minimum room temperature of 26.5oC was achieved, resulting in a maximum temperature drop of 10oC from ambient. Maximum indoor relative humidity recorded was 49%, while the outdoor relative humidity was 34%, an indication that the dehumidifying pad was able to absorb moisture from the cooled air. Maximum cooling capacity, efficiency, and COP of 3.84 kW, 84.6% and 16.1 respectively were achieved by the system without the dehumidifying pad. Corresponding values of 3.2 kW, 71.4% and 13.4 respectively were recorded when the system was operated with the dehumidifying pad.