bluuebunny/crossref_metadata_2025_split huggingface dataset:
A GeoHealth Call to Action: Moving Beyond Identifying Environmental Injustices to Co‐Creating Solutions
Authors: Hoffman‐Hall A. , Gorris M. E. , Anenberg S. , Bredder A. E. , Dhaliwal J. K. , Diaz M. A. , Fortner S. K. , McAdoo B. G. , Reano D. , Rehr R. C. , Roop H. A. , Zaitchik B. F. 
Published: October 2022

AbstractAs marginalized communities continue to bear disproportionate impacts from environmental hazards, we urgently call for researchers and institutions to elevate the principles of Environmental Justice. The American Geophysical Union (AGU) GeoHealth section supports members' engagement in health‐related community‐engaged and community‐led transdisciplinary research. We highlight intersectional research that provides examples and actions for both individuals and organizations on community science and trust building, removing barriers created by scientific agency priorities and career expectations, and opportunities in education and policy. Justice does not start or end at one meeting; this is ongoing work that is active, evolving, and an ethical responsibility of AGU's membership.
Fast Atmospheric Response to a Cold Oceanic Mesoscale Patch in the North‐Western Tropical Atlantic
Authors: Acquistapace C. , Meroni A. N. , Labbri G. , Lange D. , Späth F. , Abbas S. , Bellenger H. 
Published: October 2022

AbstractLow‐level clouds over the tropical and sub‐tropical oceans play a crucial role in the planetary radiative energy budget. However, they are challenging to model in climate simulations because they are affected by local processes that are still partially unknown. The control that mesoscale sea surface temperature (SST) structures have on the dynamics of the lower atmosphere on daily scales is emerging to be non‐negligible and calls for more effort to be understood. During the EUREC4A field campaign, two of the research vessels (R/Vs) involved in the experiment sampled the edge of a cold mesoscale SST patch in the north‐western tropical Atlantic, crossing a gradient of roughly 0.75°C/100 km. The comprehensive set of instruments carried by the R/Vs allows an unprecedented characterization of the atmospheric response to the cold water forcing. The cold ocean patch weakens the vertical atmospheric mixing, reducing the boundary layer depth of roughly 200 m and the horizontal wind intensity of approximately 3 m s−1. At the same time, the humidity content in the sub‐cloud layer increases and these conditions decrease the latent heat flux (by roughly 80 W m−2) and reduce vertical velocity fluctuations, making it less likely that moisture exceeds the lifting condensation level. As a consequence, fewer and thinner low‐level clouds form over cold water. Independent satellite measurements are found to agree with the in situ observations. The observed link between sea temperature and low‐level clouds highlights its importance in the puzzle of modeling the sea‐air‐cloud interactions.
Abrupt Change in the Lower Thermospheric Mean Meridional Circulation During Sudden Stratospheric Warmings and Its Impact on Trace Species
Authors: Orsolini Yvan J. , Zhang Jiarong , Limpasuvan Varavut 
Published: October 2022

AbstractBased on the hourly output from the 2000–2014 simulations of the National Center for Atmospheric Research's vertically extended version of the Whole Atmosphere Community Climate Model in specified dynamics configuration, we examine the roles of planetary waves (PWs), gravity waves, and atmospheric tides in driving the mean meridional circulation (MMC) in the lower thermosphere (LT) and its response to the sudden stratospheric warming phenomenon with an elevated stratopause in the northern hemisphere. Sandwiched between the two summer‐to‐winter overturning circulations in the mesosphere and the upper thermosphere, the climatological LT MMC is a narrow gyre that is characterized by upwelling in the middle winter latitudes, equatorward flow near 120 km, and downwelling in the middle and high summer latitudes. Following the onset of the sudden stratospheric warmings, this gyre reverses its climatological direction, resulting in a “chimney‐like” feature of un‐interrupted polar descent from the altitude of 150 km down to the upper mesosphere. This reversal is driven by the westward‐propagating PWs, which exert a brief but significant westward forcing between 70 and 125 km, exceeding gravity wave and tidal forcings in that altitude range. The attendant polar descent potentially leads to a short‐lived enhanced transport of nitric oxide into the mesosphere (with excess in the order of 1 parts per million), while carbon dioxide is decreased.
Visualization of estimated prevalence of CES-D positivity accounting for background factors and AIS scores
Authors: Matsuyama Takashi , Narita Akira , Takanashi Masaki , Kogure Mana , Sato Shuichi , Nakamura Tomohiro , Nakane Hideo , Ogishima Soichi , Nagami Fuji , Nakaya Naoki , Tanno Kozo , Imaeda Takao , Hozawa Atsushi 
Published: October 2022

AbstractDevelopment of methods for population screening is necessary to improve the efficiency of secondary prevention of diseases. Until now, a common cutoff has been used for all people in the data set. However, if big data for health information can be used to modify individual cutoffs according to background factors, it may avoid wasting medical resources. Here we show that the estimated prevalence of the Center for Epidemiologic Studies Depression Scale positivity can be visualized by a heatmap using background factors from epidemiological big data and scores from the Athens Insomnia Scale. We also show that cutoffs based on the estimated prevalence can be used to decrease the number of people screened without decreasing the number of prevalent cases detected. Since this method can be applied to the screening of different outcomes, we believe our work can contribute to the development of efficient screening methods for various diseases.
Self-reported visual impairment and sarcopenia among older people in Cameroon
Authors: Metanmo Salvatore , Kuate-Tegueu Callixte , Gbessemehlan Antoine , Dartigues Jean-Francois , Ntsama Marie-Josiane , Nguegang Yonta Laurella , Kengne Andre-Pascal , Simo-Tabue Nadine , Tabue-Teguo Maturin 
Published: October 2022

AbstractAging has been clearly associated with decline in visual and physical performance. Alteration of visual function is associated with negative health outcomes including physical frailty. We assessed the relationship between Visual Impairment (VI) and sarcopenia in older persons in Cameroon. In a cross-sectional survey conducted in Douala in 2019, sarcopenia was assessed using the SPPB (Short Physical Performance Battery) test scored from 0 to 12. The diagnosis of sarcopenia was based on SPPB test score < 9 while VI was self-reported. Of the 403 participants (50.4% male) with a mean age of 67.1 (± 6.2) years, 356 (88.3%) reported a VI while the prevalence of sarcopenia was 47.9% [95% CI 43.0–52.7]. After adjusting for several factors, VI was significantly associated with sarcopenia (OR 2.66 [95% CI 1.29–5.48]). Of the SPPB subtests, only chair stand test was negatively associated with VI (β = − 0.45 [95% CI − 0.82 to 0.07]). Our study supports an association between VI and sarcopenia. If confirmed by further cohort studies, this result would suggest that VI could be considered as an early indicator of sarcopenia among older people in sub-Saharan Africa.
Melatonin inhibits muscular-mucosal stretch-sensitive bladder afferents via the MT2 receptors
Authors: Ramsay Stewart , Zagorodnyuk Vladimir 
Published: October 2022

AbstractMelatonin is a circadian rhythm regulator capable of controlling a variety of physiological processes in the body. It predominantly acts via the melatonin 1 (MT1) and MT2 receptors expressed in the CNS neurons and peripheral organs and tissues. Melatonin can modulate urinary bladder function, however, to date it is not known if melatonin can regulate activity of sensory neurons innervating the bladder. Bladder afferents play an important role in urine storage and voiding. Therefore, this study aims to determine if melatonin can regulate mechanosensitivity of 2 major classes of sensory neurons in the guinea pig bladder: stretch-insensitive mucosal and low threshold stretch-sensitive muscular-mucosal afferents. The effects of melatonin on the mechanosensitivity of mucosal and muscular-mucosal afferents were measured ex vivo using single unit extracellular recording. Melatonin did not affect the responses of mucosal afferents to stroking of their receptive fields but did concentration-dependently, significantly inhibit 69% of muscular-mucosal afferents responses to stroking and bladder stretch. This inhibitory effect was not affected by the MT1 receptor antagonist, S26131 but was blocked by the selective MT2 receptor antagonists, K-185 and 4-P-PDOT. Forskolin significantly potentiated the responses of muscular-mucosal afferents to stroking and stretch, which were prevented by melatonin. These findings demonstrate a direct inhibitory effect of melatonin on the mechanosensitivity of low threshold stretch-sensitive muscular-mucosal bladder afferents acting via MT2 receptors, which is independent from its action on detrusor muscle. This may have important clinical implications for the treatment of many common bladder disorders including nocturia.
Biaxial tensile test and meso damage numerical simulation of HTPB propellant
Authors: Wang Qizhou , Wang Guang , Wang Zhejun , Qiang Hongfu , Wang Xueren , Li Shiqi , Zhu Zhaojun 
Published: October 2022

AbstractAiming at the shortcomings of the current research on the mechanical properties of solid propellants under complex stress conditions, an effective cross-shaped test piece configuration and variable-scale biaxial tensile test method are designed in this paper, and the meso-simulation model of propellant is constructed by Micro-CT test and random filling algorithm. Then, based on the Hook-Jeeves method and the cohesive force model, the mechanical performance parameters of each mesoscopic component were obtained, and finally the damage evolution process of the propellant was numerically simulated. The results show that the stress–strain curve of the propellant under biaxial loading is similar to that of uniaxial stretching, and has obvious rate dependence and stress state dependence. The mechanical properties of the propellant under biaxial tensile loading are significantly lower than those in uniaxial stretching, and the maximum elongation is only 45–85% of that in uniaxial stretching. The fracture process of propellant can be divided into initial linear stage, damage evolution stage and fracture stage. The dewetting phenomenon generally occurs at the interface between the large-sized AP particles and the matrix. With the loading of the load, the pores formed by the dewetting and matrix tearing continue to converge into cracks and expand in the direction perpendicular to the resultant force, and finally fracture. The propellant dehumidifies more easily under high strain rate loading, but the degree of dewetting is lower when the same strain is reached.
Observation and diagnostic application of Kr K-shell emission in magnetized liner inertial fusion experiments at Z
Authors: Clapp J. T. , Mancini R. C. , Harding E. C. , Schaeuble M. A. , Harvey-Thompson A. J. 
Published: October 2022

In a series of Magnetized Liner Inertial Fusion (MagLIF) experiments performed at the Z pulsed power accelerator of Sandia National Laboratories, beryllium liners filled with deuterium gas pressures in the 4–8 atm range and a tracer amount of krypton were imploded. At the collapse of the cylindrical implosion, temperatures in the 1–3 keV range and atom number densities of ∼1023 cm−3 were expected. The plasma was magnetized with a 10 T axial magnetic field. Krypton was added to the fuel for diagnosing implosion plasma conditions. Krypton K-shell line emission was recorded with the CRITR time-integrated transmission crystal x-ray spectrometer. The observation shows n = 2 to n = 1 line emissions in B-, Be-, Li-, and He-like Kr ions and is characteristic of the highest electron temperatures achieved in the thermonuclear plasma. Detailed modeling of the krypton atomic kinetics and radiation physics permits us to interpret the composite spectral feature, and it demonstrates that the spectrum is temperature sensitive. We discuss temperatures extracted from the krypton data analysis for experiments performed with several filling pressures.
Solid-state synthesis of UV-plasmonic Cr2N nanoparticles
Authors: Karaballi Reem A. , Monfared Yashar Esfahani , Bicket Isobel C. , Coridan Robert H. , Dasog Mita 
Published: October 2022

Materials that exhibit plasmonic response in the UV region can be advantageous for many applications, such as biological photodegradation, photocatalysis, disinfection, and bioimaging. Transition metal nitrides have recently emerged as chemically and thermally stable alternatives to metal-based plasmonic materials. However, most free-standing nitride nanostructures explored so far have plasmonic responses in the visible and near-IR regions. Herein, we report the synthesis of UV-plasmonic Cr2N nanoparticles using a solid-state nitridation reaction. The nanoparticles had an average diameter of 9 ± 5 nm and a positively charged surface that yields stable colloidal suspension. The particles were composed of a crystalline nitride core and an amorphous oxide/oxynitride shell whose thickness varied between 1 and 7 nm. Calculations performed using the finite element method predicted the localized surface plasmon resonance (LSPR) for these nanoparticles to be in the UV-C region (100–280 nm). While a distinctive LSPR peak could not be observed using absorbance measurements, low-loss electron energy loss spectroscopy showed the presence of surface plasmons between 80 and 250 nm (or ∼5 to 15 eV) and bulk plasmons centered around 50–62 nm (or ∼20 to 25 eV). Plasmonic coupling was also observed between the nanoparticles, resulting in resonances between 250 and 400 nm (or ∼2.5 to 5 eV).
Speaking in the first-person singular or plural
Authors: Liu Nannan 
Published: October 2022

AbstractConventionally, the professional interpreter speaks in the first-person singular. Research in corpus-based discourse analysis has reported shifts from this norm towards first-person plural becoming the most frequent pronoun shift in political institutional interpreting, possibly signalling interpreter ‘alignment with the institution’. Nonetheless, few studies have teased apart the simultaneous constraints of social, cognitive, and linguistic factors on institutional interpreters’ preference for the plural. The present research adopts the usage-based theory to consider the three types of explanations together. It extends recent multivariate methodologies based on this theory to analyse 2,438 first-person cases in parallel interpreting and comparable speech corpora. Following robust context analyses and cross-linguistic prosodic transcription, this study weighs the strengths of 33 associates regarding the three explanations through regression analyses. The results show that first-person shifts are better explained by chunking effects when interpreters process complex forms and referents in the source and target speeches, and when they process zero-subject source inputs. The institutional alignment explanation fails to account for the extensive grammaticalisation of plural constructions in the interpreted speech. When all the interactive and additive effects are considered together, institutional alignment or monofactorial paradigms have little explanatory power. This study concludes by highlighting the relevance of usage-based multifactorial designs to interpreting research.
The politics of literal translation in Soviet Ukraine
Authors: Kolomiyets Lada 
Published: October 2022

Abstract
Nikolai Gogol (Ukrainian: Mykola Hoholʹ) is a notable example of a nineteenth-century Russian author of Ukrainian
origin, whose works in Ukrainian translation have always been and now remain ideologically fraught. This article discusses the
dynamics of translation – from creative stylization to awkward literalism – during the period from the late 1920s to the early
1950s. Later Ukrainian editions of Gogol’s works in the Ukrainian SSR were not substantially different from those published in the
mid-1950s, which indicates that by that time the Soviet model of Ukrainian literary language had been firmly established. It
tended to increasingly merge with Russian, taking the Russian-language writings of Gogol as a model. The study reveals a tension
between Ukrainian national idealism and the Soviet regime’s pragmatic use of language as a means of political propaganda. The
discussion further challenges Russian-to-Ukrainian literalism as a strategy for manufacturing linguistic similarities and
“naturalizing” Russian as the mother tongue.
Electrolyte considerations in targeted temperature management
Authors: Barlow Brooke , Landolf Kaitlin , LaPlante Reid , Cercone Jessica , Kim Ji-Yeon , Ghorashi Sona , Howell Alexandria , Armahizer Michael , Heavner Mojdeh S 
Published: October 2022

AbstractPurposeTargeted temperature management (TTM), including normothermia and therapeutic hypothermia, is used primarily for comatose patients with return of spontaneous circulation after cardiac arrest or following neurological injury. Despite the potential benefits of TTM, risks associated with physiological alterations, including electrolyte shifts, may require intervention.SummaryThis review describes the normal physiological balance of electrolytes and temperature-related alterations as well as the impact of derangements on patient outcomes, providing general recommendations for repletion and monitoring of key electrolytes, including potassium, phosphate, and magnesium.ConclusionFrequent monitoring and consideration of patient variables such as renal function and other risk factors for adverse effects are important areas of awareness for clinicians caring for patients undergoing TTM.
Double administration of self-complementary AAV9NDUFS4 prevents Leigh disease in Ndufs4−/− mice
Authors: Corrà Samantha , Cerutti Raffaele , Balmaceda Valeria , Viscomi Carlo , Zeviani Massimo 
Published: October 2022

Abstract
Leigh disease, or subacute necrotizing encephalomyelopathy, a genetically heterogeneous condition consistently characterized by defective mitochondrial bioenergetics, is the most common oxidative-phosphorylation related disease in infancy. Both neurological signs and pathological lesions of Leigh disease are mimicked by the ablation of the mouse mitochondrial respiratory chain subunit Ndufs4−/−, which is part of, and crucial for, normal Complex I activity and assembly, particularly in the brains of both children and mice. We previously conveyed the human NDUFS4 gene to the mouse brain using either single-stranded adeno-associated viral 9 recombinant vectors or the PHP.B adeno-associated viral vector. Both these approaches significantly prolonged the lifespan of the Ndufs4−/− mouse model but the extension of the survival was limited to a few weeks by the former approach, whereas the latter was applicable to a limited number of mouse strains, but not to primates. Here, we exploited the recent development of new, self-complementary adeno-associated viral 9 vectors, in which the transcription rate of the recombinant gene is markedly increased compared with the single-stranded adeno-associated viral 9 and can be applied to all mammals, including humans. Either single intra-vascular or double intra-vascular and intra-cerebro-ventricular injections were performed at post-natal Day 1. The first strategy ubiquitously conveyed the human NDUFS4 gene product in Ndufs4−/− mice, doubling the lifespan from 45 to ≈100 days after birth, when the mice developed rapidly progressive neurological failure. However, the double, contemporary intra-vascular and intra-cerebroventricular administration of self-complementary-adeno-associated viral NDUFS4 prolonged healthy lifespan up to 9 months of age. These mice were well and active at euthanization, at 6, 7, 8 and 9 months of age, to investigate the brain and other organs post-mortem. Robust expression of hNDUFS4 was detected in different cerebral areas preserving normal morphology and restoring Complex I activity and assembly. Our results warrant further investigation on the translatability of self-complementary-adeno-associated viral 9 NDUFS4-based therapy in the prodromal phase of the disease in mice and eventually humans.
Social cognition deficits and biometric signatures in the behavioural variant of Alzheimer’s disease
Authors: Singleton Ellen H , Fieldhouse Jay L P , van ’t Hooft Jochum J , Scarioni Marta , van Engelen Marie-Paule E , Sikkes Sietske A M , de Boer Casper , Bocancea Diana I , van den Berg Esther , Scheltens Philip , van der Flier Wiesje M , Papma Janne M , Pijnenburg Yolande A L , Ossenkoppele Rik 
Published: October 2022

Abstract
The behavioural variant of Alzheimer’s disease (bvAD) is characterized by early predominant behavioural changes, mimicking the behavioural variant of frontotemporal dementia (bvFTD), which is characterized by social cognition deficits and altered biometric responses to socioemotional cues. These functions remain understudied in bvAD.
We investigated multiple social cognition components (i.e. emotion recognition, empathy, social norms and moral reasoning), using the Ekman 60 faces test, Interpersonal Reactivity Index, empathy eliciting videos, Social Norms Questionnaire and moral dilemmas, while measuring eye movements and galvanic skin response. We compared 12 patients with bvAD with patients with bvFTD (n = 14), typical Alzheimer’s disease (tAD, n = 13) and individuals with subjective cognitive decline (SCD, n = 13), using ANCOVAs and age- and sex-adjusted post hoc testing.
Patients with bvAD (40.1 ± 8.6) showed lower scores on the Ekman 60 faces test compared to individuals with SCD (49.7 ± 5.0, P &lt; 0.001), and patients with tAD (46.2 ± 5.3, P = 0.05) and higher scores compared to patients with bvFTD (32.4 ± 7.3, P = 0.002). Eye-tracking during the Ekman 60 faces test revealed no differences in dwell time on the eyes (all P &gt; 0.05), but patients with bvAD (18.7 ± 9.5%) and bvFTD (19.4 ± 14.3%) spent significantly less dwell time on the mouth than individuals with SCD (30.7 ± 11.6%, P &lt; 0.01) and patients with tAD (32.7 ± 12.1%, P &lt; 0.01). Patients with bvAD (11.3 ± 4.6) exhibited lower scores on the Interpersonal Reactivity Index compared with individuals with SCD (15.6 ± 3.1, P = 0.05) and similar scores to patients with bvFTD (8.7 ± 5.6, P = 0.19) and tAD (13.0 ± 3.2, P = 0.43). The galvanic skin response to empathy eliciting videos did not differ between groups (all P &gt; 0.05). Patients with bvAD (16.0 ± 1.6) and bvFTD (15.2 ± 2.2) showed lower scores on the Social Norms Questionnaire than patients with tAD (17.8 ± 2.1, P &lt; 0.05) and individuals with SCD (18.3 ± 1.4, P &lt; 0.05). No group differences were observed in scores on moral dilemmas (all P &gt; 0.05), while only patients with bvFTD (0.9 ± 1.1) showed a lower galvanic skin response during personal dilemmas compared with SCD (3.4 ± 3.3 peaks per min, P = 0.01).
Concluding, patients with bvAD showed a similar although milder social cognition profile and a similar eye-tracking signature to patients with bvFTD and greater social cognition impairments and divergent eye movement patterns compared with patients with tAD. Our results suggest reduced attention to salient facial features in these phenotypes, potentially contributing to their emotion recognition deficits.