bluuebunny/crossref_metadata_2025_split huggingface dataset:
Temperature and interlayer coupling induced thermal transport across graphene/2D-SiC van der Waals heterostructure
Authors: Islam Md. Sherajul , Mia Imon , Islam A. S. M. Jannatul , Stampfl Catherine , Park Jeongwon 
Published: January 2022

AbstractGraphene based two-dimensional (2D) van der Waals (vdW) materials have attracted enormous attention because of their extraordinary physical properties. In this study, we explore the temperature and interlayer coupling induced thermal transport across the graphene/2D-SiC vdW interface using non-equilibrium molecular dynamics and transient pump probe methods. We find that the in-plane thermal conductivity κ deviates slightly from the 1/T law at high temperatures. A tunable κ is found with the variation of the interlayer coupling strength χ. The interlayer thermal resistance R across graphene/2D-SiC interface reaches 2.71 $$\times$$
×
10–7$${\text{Km}}^{2} /{\text{W}}$$

Km

2

/
W

at room temperature and χ = 1, and it reduces steadily with the elevation of system temperature and χ, demonstrating around 41% and 56% reduction with increasing temperature to 700 K and a χ of 25, respectively. We also elucidate the heat transport mechanism by estimating the in-plane and out-of-plane phonon modes. Higher phonon propagation possibility and Umklapp scattering across the interface at high temperatures and increased χ lead to the significant reduction of R. This work unveils the mechanism of heat transfer and interface thermal conductance engineering across the graphene/2D-SiC vdW heterostructure.
Non-conventional superconductivity in magnetic In and Sn nanoparticles
Authors: Ma Ma-Hsuan , Batsaikhan Erdembayalag , Chen Huang-Nan , Chen Ting-Yang , Lee Chi-Hung , Li Wen-Hsien , Wu Chun-Ming , Wang Chin-Wei 
Published: January 2022

AbstractWe report on experimental evidence of non-conversional pairing in In and Sn nanoparticle assemblies. Spontaneous magnetizations are observed, through extremely weak-field magnetization and neutron-diffraction measurements, to develop when the nanoparticles enter the superconducting state. The superconducting transition temperature TC shifts to a noticeably higher temperature when an external magnetic field or magnetic Ni nanoparticles are introduced into the vicinity of the superconducting In or Sn nanoparticles. There is a critical magnetic field and a critical Ni composition that must be reached before the magnetic environment will suppress the superconductivity. The observations may be understood when assuming development of spin-parallel superconducting pairs on the surfaces and spin-antiparallel superconducting pairs in the core of the nanoparticles.
Experimental evaluation of a new carrier‐based modulation method for a three‐level T‐type quasi‐impedance‐source inverter
Authors: Gutiérrez‐Escalona Javier , Roncero‐Clemente Carlos , Barrero‐González Fermín , Husev Oleksandr , González‐Romera Eva , Milanés‐Montero María Isabel 
Published: January 2022

AbstractQuasi‐impedance‐source inverter topologies require the insertion of short‐circuit states of the DC‐link to achieve the boost feature. Unlike traditional strategies that implement full short‐circuits in the legs of the inverter, new control methods based on space vector modulation (SVM) introduce these states by alternately short‐circuiting the two halves of the DC‐link, improving the harmonic performance and efficiency of the converter. However, because of the complexity involved in the implementation of these SVM strategies, simpler and more direct control techniques are needed. In this study, a new carrier‐based strategy for the control of a three‐level T‐Type quasi‐Z‐source inverter (qZS 3L‐TI), which implements the half‐DC‐link short‐circuit states, is validated through several experimental tests under rated power conditions. The experimental results indicate that the new carrier‐based technique shows improved harmonic performance, lower semiconductor stress, and a better efficiency than the traditional full shoot‐through strategy. Based on these results and the simplicity of implementation, the new carrier‐based control strategy proves to be a competitive alternative for the control of qZS 3L‐TI.
Endoscopic characterization of colorectal neoplasia with different published classifications: comparative study involving CONECCT classification
Authors: Bonniaud Paul , Jacques Jérémie , Lambin Thomas , Gonzalez Jean-Michel , Dray Xavier , Coron Emmanuel , Leblanc Sarah , Chevaux Jean-Baptiste , Léger-Nguyen Florence , Hamel Benjamin , Lienhart Isabelle , Rivory Jérôme , Ponchon Thierry , Saurin Jean-Christophe , Monzy Frédéric , Legros Romain , Lépilliez Vincent , Subtil Fabien , Barret Maximilien , Pioche Mathieu 
Published: January 2022

Abstract
Background and study aims The aim of this study was to validate the COlorectal NEoplasia Classification to Choose the Treatment (CONECCT) classification that groups all published criteria (including covert signs of carcinoma) in a single table.
Patients and methods For this multicenter comparative study an expert endoscopist created an image library (n = 206 lesions; from hyperplastic to deep invasive cancers) with at least white light Imaging and chromoendoscopy images (virtual ± dye based). Lesions were resected/biopsied to assess histology. Participants characterized lesions using the Paris, Laterally Spreading Tumours, Kudo, Sano, NBI International Colorectal Endoscopic Classification (NICE), Workgroup serrAted polypS and Polyposis (WASP), and CONECCT classifications, and assessed the quality of images on a web-based platform. Krippendorff alpha and Cohen’s Kappa were used to assess interobserver and intra-observer agreement, respectively. Answers were cross-referenced with histology.
Results Eleven experts, 19 non-experts, and 10 gastroenterology fellows participated. The CONECCT classification had a higher interobserver agreement (Krippendorff alpha = 0.738) than for all the other classifications and increased with expertise and with quality of pictures. CONECCT classification had a higher intra-observer agreement than all other existing classifications except WASP (only describing Sessile Serrated Adenoma Polyp). Specificity of CONECCT IIA (89.2, 95 % CI [80.4;94.9]) to diagnose adenomas was higher than the NICE2 category (71.1, 95 % CI [60.1;80.5]). The sensitivity of Kudo Vi, Sano IIIa, NICE 2 and CONECCT IIC to detect adenocarcinoma were statistically different (P < 0.001): the highest sensitivities were for NICE 2 (84.2 %) and CONECCT IIC (78.9 %), and the lowest for Kudo Vi (31.6 %).
Conclusions The CONECCT classification currently offers the best interobserver and intra-observer agreement, including between experts and non-experts. CONECCT IIA is the best classification for excluding presence of adenocarcinoma in a colorectal lesion and CONECCT IIC offers the better compromise for diagnosing superficial adenocarcinoma.
Expertise in colonoscopy intubation does not predict diagnostic accuracy: a simulation-based study
Authors: Vilmann Andreas S. , Lachenmeier Christian , Svendsen Morten Bo S. , Soendergaard Bo , Park Yoon S. , Svendsen Lars Bo , Konge Lars 
Published: January 2022

Abstract
Background and study aims Studies have linked cecal intubation rate with adenoma detection rate; however, the direct association between technical performance during colonoscopy intubation and withdrawal has never been explored. Thus, it remains unclear whether gentle and efficient intubation predicts superior mucosal inspection. The aim of this study was to investigate the correlation between performance during intubation and withdrawal in a simulation-based setup.
Methods Twenty-four physicians with various experience in colonoscopy performed twice on the Endoscopy Training System (ETS). Intubation skills were evaluated by assessing tasks on the ETS related to intubation (scope manipulation and loop management) and use of a computerized assessment tool called the 3D-Colonoscopy Progression Score (3D-CoPS). Diagnostic accuracy was defined by the number of polyps found during the ETS task of mucosal inspection. Pearson’s correlations were calculated to explore associations between intubation skill and diagnostic accuracy.
Results The correlation analysis between 3D-CoPS and number of polyps found during mucosal inspection revealed a weak and insignificant correlation (0.157, P = 0.3). Likewise, an insignificant correlation was seen between ETS intubation and number of polyps found (0.149, P = 0.32).
Conclusions We found no evidence to support that technical performance during intubation is correlated with mucosal inspection performance in a simulation-based setting.
Identification of diverticular bleeding needs early colonoscopy rather than preparation
Authors: Mizuki Akira , Tatemichi Masayuki , Nakazawa Atsushi , Tsukada Nobuhiro , Nagata Hiroshi , Kanai Takanori 
Published: January 2022

Abstract
Background and study aims When patients present with acute colonic diverticulum bleeding (CDB), a colonoscopy is performed to identify stigmata of recent hemorrhage (SRH), but valuable time can be lost in bowel preparation. This study retrospectively examined groups of patients who either had a standard pre-colonoscopy regimen or no preparation.
Patients and methods This study compared data from 433 patients who either followed a lengthy regimen of bowel preparation (prepared group, 266 patients) or had no preparation (unprepared group, 60 patients). We compared the association between time (hours) between admission before starting a colonoscopy (TMS) and identification of SRH using a chi-square test.
Results In 48 of 60 cases (80.0 %) in the unprepared group, a total colonoscopy was performed and the time to identify SRH was decreased. The respective rates of SRH identification in the unprepared and prepared groups were 55.2 % (16/29) vs. 46.7 % (7/15) if the TMS was < 3 hours; 47.1 % (8/7) vs. 36.8 % (35/95) in 3 to 12 hours; 0 % (0/3) vs. 22.0% (13/59) in 12 to 18 hours; and 21.8 % (3/11) vs. 20.6% (42/204) in > 18 hours. There were no significant differences between the two groups. However, the SRH identification rates before and after 12 hours were 42.3 % (66/156) and 20.9 % (58/277) (P < 0.001).
Conclusions Our data suggest that the bowel preparation method before colonoscopy is an independent variable predicting success in identifying SRH among patients with CDB. Decreasing the time before colonoscopy to no more than 12 hours after admission played an important role in identifying SRH.
Impact of preoperative endoscopy for predicting treatment response and prognosis in patients with gastric cancer after neoadjuvant chemotherapy
Authors: Shoji Yoshiaki , Nunobe Souya , Nishie Naoki , Yagi Shusuke , Makuuchi Rie , Ida Satoshi , Kumagai Koshi , Ohashi Manabu , Ishiyama Akiyoshi , Yoshio Toshiyuki , Hirasawa Toshiaki , Fujisaki Junko , Sano Takeshi 
Published: January 2022

Abstract
Background and study aims Response evaluation criteria in solid tumors (RECIST) have been the gold standard to preoperatively predict treatment response and prognosis in patients with gastric cancer (GC) after neoadjuvant chemotherapy (NAC); however, methods for patients without evaluable lesions by RECIST are not yet confirmed. The aim of this study was to assess the utility of preoperative endoscopy for predicting treatment response and prognosis in patients with GC after NAC.
Patients and methods This retrospective study included 105 patients with initially resectable GC who underwent NAC followed by surgical treatment. Preoperative factors for predicting treatment response and survival outcomes were analyzed.
Results The number of patients classified as responders using preoperative endoscopic assessment, RECIST, and postoperative pathological evaluation were 25 (23.8 %), 28 (26.7 %), and 18 (17.1 %), respectively. Forty-three patients (41 %) were classified as non-targeted disease only, and their treatment responses were not evaluable by RECIST. Multivariate analysis identified endoscopic response as an independent preoperative factor to predict postoperative histological treatment response (odds ratio = 4.556, 95 % CI = 1.169–17.746, P = 0.029). Endoscopic treatment response was the only independent preoperative predictive factor for overall survival (OS) (hazard ratio = 0.419, 95 % confidence interval (CI) = 0.206–0.849, P = 0.016). Further, endoscopic treatment response was available for 33 patients (76.7 %) with non-targeted disease only, which showed significantly different OS between endoscopic responders (80.0 %) and non-responders (43.5 %) (P = 0.025).
Conclusions Endoscopic evaluation was an independent preoperative factor to predict treatment response and prognosis in patients with GC after NAC. Endoscopic assessment may be especially valuable for patients who could not be assessed by RECIST.
Facile Synthesis of Quinoxaline-2-thiol and Quinoxaline from α-Oxosulfines and o-Arylenediamines
Authors: Dong Jun , Huang Xingcai , Chen Youwei 
Published: January 2022

AbstractA series of quinoxaline-2-thiols and quinoxalines were prepared in moderate to good yields from various phenacyl sulfoxides bearing 1-methyl-1H-tetrazole and o-arylenediamines. The proposed reaction mechanism involves generation of sulfines from the phenacyl sulfoxides bearing 1-methyl-1H-tetrazole through thermolysis elimination. Then, site-selective carbophilic addition of sulfines by o-arylenediamines, followed by elimination, intramolecular nucleophilic addition, and dehydration condensation. The current method provides a direct and simple strategy for the preparation of quinoxaline-2-thiols and quinoxalines.
Conjugated Nanohoops with Dibenzo[a,e]pentalenes as Nonalternant and Antiaromatic π-Systems
Authors: Esser Birgit , Wössner Jan S. , Hermann Mathias 
Published: January 2022

AbstractConjugated nanohoops are excellent as candidates for studying structure–property relationships, as optoelectronic materials, and as hosts for supramolecular chemistry. Whereas carbon nanohoops containing aromatics have been well studied, antiaromatic units had not been incorporated until our group recently did so, using dibenzo[a,e]pentalene (DBP). The nonalternant electronic character of the DBP units significantly influences the optoelectronic properties of such nanohoops. Here, we summarize our synthetic strategies toward DBP-containing nanohoops, together with their structural and electronic properties, chirality, and host–guest chemistry. We demonstrate how incorporating antiaromatic units leads to unique properties and opens new synthetic avenues, making such nanohoops attractive as potential electronic materials.1 Introduction2 Synthesis3 Structural Properties4 Electronic Properties5 Chirality6 Host–Guest Chemistry
Tuning the Electrochemical and Photophysical Properties of Osmium-Based Photoredox Catalysts
Authors: Bednářová Eva , Beck Logan R. , Rovis Tomislav , Goldschmid Samantha L. , Xie Katherine , Tay Nicholas E. S. , Ravetz Benjamin D. , Li Jun , Joe Candice L. 
Published: January 2022

AbstractThe use of low-energy deep-red (DR) and near-infrared (NIR) light to excite chromophores enables catalysis to ensue across barriers such as materials and tissues. Herein, we report the detailed photophysical characterization of a library of OsII polypyridyl photosensitizers that absorb low-energy light. By tuning ligand scaffold and electron density, we access a range of synthetically useful excited state energies and redox potentials.1 Introduction1.1 Scope1.2 Measuring Ground-State Redox Potentials1.3 Measuring Photophysical Properties1.4 Synthesis of Osmium Complexes2 Properties of Osmium Complexes2.1 Redox Potentials of Os(L)2-Type Complexes2.2 Redox Potentials of Os(L)3-Type Complexes2.3 UV/Vis Absorption and Emission Spectroscopy3 Conclusions
Postacute-Stroke Management Problems in Home Care Service: A Qualitative Single-Centered Study in Yogyakarta, Indonesia
Authors: Paryono Paryono , Ar Rochmah Mawaddah , Setyopranoto Ismail , Trisnantoro Laksono 
Published: January 2022

Abstract

Objective This study explores the postacute-stroke management problems, particularly for patients with total dependency (Barthel Index <20), in home care service of Dr. Sardjito Hospital (SH) from the hospital personnel's and caregiver's points of view.

Materials and Methods In-depth interviews with a semi-structured interview guide were conducted with hospital personnel and patients' caregivers based on the purposeful sampling. There were 10 hospital personnel that were interviewed: the director of medical service, head of home care unit, neurologists, general practitioners, nurses, and physiotherapist. There were eight caregivers who participated in the study.

Statistical Analysis Data from the interviews were analyzed using systematic text condensation using Nvivo 12 plus.

Results Our findings showed that all health personnel in SH agreed that home care service is a part of an integrated health care service for continuation of care. However, the preparedness by the hospital management is still lacking in infrastructures, such as standardized operational procedure, quality control, and financial system, as well as in terms of competent human resources and their welfare. In addition, the patient's family and caregiver are lacking in knowledge and independency to take care of the patients with the need of home care services' monitoring to deliver the expected home care for postacute-stroke's patient regularly.

Conclusion Home care service is an act of implementing hospital obligation to fulfill the patients' rights. An established hospital policy to ensure a comprehensive home care service delivery is necessary. The capability and welfare of the health care personnel should be put into account for the standardized human resources.
Regional synapse gain and loss accompany memory formation in larval zebrafish
Authors: Dempsey William P. , Du Zhuowei , Nadtochiy Anna , Smith Colton D. , Czajkowski Karl , Andreev Andrey , Robson Drew N. , Li Jennifer M. , Applebaum Serina , Truong Thai V. , Kesselman Carl , Fraser Scott E. , Arnold Don B. 
Published: January 2022

Significance
Imaging of labeled excitatory synapses in the intact brain before and after classical conditioning permits a longitudinal analysis of changes that accompany associative memory formation. When applied to midlarval stage zebrafish, this approach reveals adjacent regions of synapse gain and loss in the lateral and medial pallium, respectively. Such major structural changes could account for the robust nature of memory formation from classical conditioning.
CD169+macrophages in lymph node and spleen critically depend on dual RANK and LTbetaR signaling
Authors: Camara Abdouramane , Lavanant Alice C. , Abe Jun , Desforges Henri Lee , Alexandre Yannick O. , Girardi Erika , Igamberdieva Zinaida , Asano Kenichi , Tanaka Masato , Hehlgans Thomas , Pfeffer Klaus , Pfeffer Sébastien , Mueller Scott N. , Stein Jens V. , Mueller Christopher G. 
Published: January 2022

SignificanceThe CD169+macrophages that play an important role in the fight against infections and cancer are receptive to environmental signals for their differentiation. We show that lymph node and splenic CD169+macrophages require both LTβR and RANK signaling since the conditional deficiency of either receptor results in their disappearance. Using a reporter mouse, we observe RANKL expression by a splenic mesenchymal cell subset and show that it participates in CD169+macrophage differentiation. Their absence leads to a reduced viral capture and a greatly attenuated virus-specific CD8+T cell expansion. Thus, tight control mechanisms operate for the precise positioning of these macrophages at sites where numerous immune-stimulatory forces converge.
Targeted vaccination and the speed of SARS-CoV-2 adaptation
Authors: Gandon Sylvain , Lion Sébastien 
Published: January 2022

Significance
The ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) raises an important question: who should we vaccinate first? Answering this question requires an analysis of both the short-term (epidemiological) and the long-term (evolutionary) consequences of targeted vaccination strategies. We analyze the speed of pathogen adaptation and the cumulative number of deaths in heterogeneous host populations to shed light on the effects of alternative vaccination strategies. This analysis shows that minimizing the speed of pathogen adaptation does not always minimize the number of deaths. This evaluation of both the epidemiological and evolutionary consequences of public health policies provides a practical tool to identify the best vaccination strategy.
The influence of socio-economic status, age, gender, and level of literacy on language attitudes
Authors: Ulysse Gerdine M. , Masaeed Khaled Al 
Published: January 2022

AbstractThis study investigated the relationship between socio-economic status, age, gender, and literacy level and Haitian Gonâviens‘ attitudes towards Haitian Creole or Kreyòl and French. Most studies that investigated language attitudes of Creolophones have found that they have negative attitudes towards Kreyòl. Nevertheless, previous studies often included participants who are affiliated with education such as students, teachers, and language policy makers, or those from higher social classes. The current study, however, utilized a language attitudes questionnaire to collect data from 78 adult informants from diverse backgrounds. These participants included 21 highly literate, 51 partially literate and 6 illiterate Haitians. Findings revealed that participants of higher socio-economic status have more positive attitudes towards French than those from lower socio-economic status. Results also showed that there is a tendency for age, gender, and literacy level to affect language attitudes. For instance, positive attitudes towards Kreyòl were found to be more prevalent among older participants than younger respondents. Similarly, male participants had more negative attitudes towards French than female informants. Moreover, respondents of lower literacy levels had more negative attitudes towards French than those who were highly literate.
Tourism Development in Algeria and the Horizon 2025 Plan
Authors: Azzaoui Imene , Carnicelli Sandro , Khodadadi Masood 
Published: January 2022

Abstract
Despite Algeria’s strategic geographical location as a portal to Africa from Europe and the continuous attempts to reform its tourism sector, this postcolonial country has failed to become a tourism hub in the Mediterranean area. In Algeria, the year 2008 witnessed the birth of a tourism development plan named ‘Horizon 2025’, projecting strategies and goals to be achieved by 2025. However, the plan did not achieve its expected results because of various socio-political and external issues such as the country’s recent political instability and the global Covid-19 pandemic. Surprisingly, Algeria’s domestic market has witnessed noticeable growth in the last 20 years, especially during the global pandemic. The present case study reflects on the development of the Horizon 2025 plan and its contribution to the rebranding of Algeria as a destination and the consequential outcomes that helped the growth of its domestic tourism market. Through the case study, we showcase the efforts made to build Algeria as an attractive destination and how Covid-19 challenged the plan’s forecasted goals while paving the way for the development and promotion of domestic tourism.

Information
The case study is the authors’ collaborative effort, adapted from the PhD thesis of Imene El Azzaoui
© Imene El Azzaoui 2022