bluuebunny/crossref_metadata_2025_split huggingface dataset:
The contribution of the preoperative methylene blue staining method to the surgical performance of parathyroid adenomas with difficult localization
Authors: Aksoy Erkan , Ocak Özlem Karaca , Ergenç Hasan , Ergenç Zeynep , Gökosmanoğlu Feyzi 
Published: June 2022

Abstract
IntroductionPreoperative localization of parathyroid adenomas and staining of parathyroid adenomas guided by different methods improve surgical outcomes. The purpose of the present study was to evaluate the contribution of US-guided methylene blue staining to the surgical performance of parathyroid adenomas.Material and MethodThe study was conducted in the endocrinology and general surgery clinic on 152 parathyroid adenoma patients who underwent methylene blue staining with preoperative US guidance. This application is a new method and is very different from other applications since methylene blue is administered parenterally. In the procedure, a very low-dose methylene blue is administered to the inside or wall of the parathyroid adenoma with a fine needle. The data of the patients were obtained retrospectively from patient files and electronic records.ResultsIn the present study, a total of 152 patients who had suspicious parathyroid adenomas with difficult localization and a history of previous surgical failure were stained with methylene blue in the preoperative period. This practice was associated with minimally invasive surgery and very short operative time. The methylene blue staining method was also found to be effective in the diagnosis, localization, and treatment of parathyroid adenomas with 100% sensitivity and 100% specificity.ConclusionAs a result of the present study, it was concluded that methylene blue staining provides a guide for the excision of parathyroid adenomas, potentially improving surgical outcomes in the resection of unsuccessful attempts and ectopic parathyroid adenomas difficult to identify.
Impact of Indium concentration In0.52 Al0.48 As/Inx Ga1-x As/InP HEMT device on DC and AC performances
Authors: boursali amin , -bouazza ahlam guen 
Published: June 2022

Abstract
The main goal of this paper is to Investigate the Impact of Indium concentration In the alloy InxGa1-xAs of the channel layer .the stimulation device based on In0.52Al0.48As/InxGa1-xAs/In0.52Al0.48As In (HEMT )by using Silvaco Tacad two and three-dimensional device simulation.For each Indium concentration (In)In the alloy InxGa1-xAs some DCand ACperformances has been simulated In order to show the Influence of the Indium content .which 20 nm of gate length and thickness of 10nm of channel layer the device exhibit a maximum drain current 1.43 A for In0.1Ga0.9As,a maximum transconductance (Gm) of 1450 mS/mm ,a subthreshold voltage slope (SS)of 75 mV/decade,a gate leakage current of 10 − 5,cut-off frequency (Ft) of 400GHZ and maximum oscillation frequency (Fmax) of 860 GHz
Disentangling the Dynamics of VOCs and VOIs during the COVID-19 Pandemic in Peru using Bayesian Phylogenetics
Authors: Arevalo Santiago Justo , Silva Cinthy Jimenez , Calampa Carmen Sofia Uribe , Bouckaert Remco , Pinho Joao Renato 
Published: June 2022

Abstract
At over 0.6% of the population, Peru has the highest SARS-CoV-2 mortality rate in the world. Much effort to sequence genomes was done in this country since mid-2020. However, an adequate analysis of the dynamics of the variants of concern and interest (VOCIs) is missing. We performed Bayesian phylodynamic analyses using different sampling approaches to determine the origin of the VOCIs in Peru, as well as their population dynamics. The COVID-19 pandemic in Peru was characterized by three waves. We showed that Lambda emerged in Peru during the first wave (April-July, 2020) but it did not reach high frequencies until the second wave. Alpha and Gamma were imported to Peru between the first and second waves (October-December, 2020). The gamma variant reached Peru from Brazil, whereas Alpha arrived at Peru from the United Kingdom. Effective population size (Ne) and effective reproductive number (Rt) suggest that Lambda, followed by Gamma, dominated the second wave of COVID-19 in Peru whereas Alpha was not very prevalent. During this wave, Lambda dominated all the Peruvian regions except the Northeast, where Gamma dominated. Migration patterns of Lambda and Gamma between the Northeast and other regions indicate that the different VOCI prevalence in the Northeast was not due to the isolation of this region. Also, during the second wave, Mu and Delta arrived in Peru (February-May, 2021) from the USA and the United Kingdom, respectively. Mu never reached high Rt nor Ne; on the other hand, at the final of the second wave, Delta showed Rt values higher than other VOCIs, beginning to increase its Ne and replacing Lambda and Gamma. Finally, Omicron reached Peru just before the beginning of the third wave (October-December, 2021) from the USA. Omicron had a high Rt since its arrival to Peru, originating new lineages and rapidly increasing its Ne which caused the third wave. In summary, we were able to determine important patterns of virus dynamics in Peru using Bayesian Phylogenetics. Besides, we demonstrated that Bayesian phylodynamics with a portion of the available genomes were sufficient to reconstruct the COVID-19 pandemic in Peru.
Simulation of skin tissue temperature distribution during laser thermal pain treatment
Authors: Liu Honghua , She Chang , Huang Zhiliang , Wei Lei , Li Qian , Peng Han , Liu Mailan 
Published: June 2022

Abstract
Lasers are widely used in clinical pain research because they cause temperature changes in biological tissue, which activate nociceptors to create pain sensations. The key to thermal pain treatment lies in the temperature distribution of biological tissue caused by the laser. In order to improve the thermal pain response induced by laser, it is necessary to study the temperature distribution of biological tissue during treatment. In this paper, based on biological tissue in a special medium, combining the two modules of biological heat transfer and radiation heat transfer, a finite element model of laser thermal pain treatment is established. The model considers four factors such as laser power, and obtains the temperature distribution characteristics of biological tissue under laser irradiation through calculation under standard conditions, and then obtains the influence of different factors on temperature distribution through single factor analysis. At the end of the article, the results obtained by single factor analysis are analyzed by orthogonal test to obtain the degree of influence of different factors on temperature distribution. In clinical treatment, doctors can reasonably choose laser irradiation parameters based on the above results.
Predictive value of layer-specific speckle tracking technique combined with triglyceride-glucose index in the diagnosis of acute coronary syndrome complicated with diabetes mellitus
Authors: Liu Jiajia , Zhang Lu , Zhang Yan , Deng Aiyun 
Published: June 2022

Abstract
Background
To analyze the relationship between triglyceride-glucose (TyG) index and left ventricular systolic function and myocardial layer-specific strain in patients with acute coronary syndrome (ACS) combined with diabetes mellitus (DM) and to explore the value of layer-specific speckle tracking technique combined with TyG index in the risk assessment of patients with ACS combined with DM.
Methods
Ninety-eight patients with chest pain who underwent coronary angiography were enrolled from the Department of Cardiology in the First Hospital of Lanzhou University between October 2020 and December 2021. The TyG index was calculated based on blood test results. The two-dimensional layer-specific speckle tracking technique was used to measure the left ventricular global longitudinal strain in the endocardial layer (GLSendo), mid-myocardial layer (GLSmid) and epicardial layer (GLSepi). The multiple linear regression analysis was performed with GLSendo, GLSmid, and GLSepi as dependent variables and the TyG index as an independent variable. Then the receiver operator characteristic (ROC) curve for predicting ACS with DM was plotted based on TyG index and GLSendo.
Results
Compared with the ACS alone and control groups, the TyG index was significantly increased in ACS combined with DM group (P < 0.05). The left ventricular ejection fraction and the strain of each layer of the myocardium were significantly reduced in the ACS combined DM group, in which the global longitudinal strain value from the endocardium to the epicardium decreased gradually. Among them, GLSendo had significant differences between the ACS combined DM group and the ACS alone group (P < 0.05). The TyG index was negatively correlated with left ventricular ejection fraction and positively correlated with GLSendo, GLSmid, GLSepi, and ΔLS (GLSendo-GLSdpi) (P < 0.05). Multiple linear regression analysis revealed a linear correlation between TyG index and GLSendo, based on which the ROC curve for predicting ACS with DM was plotted, with the area under the curve of 0.896 (P < 0.001).
Conclusions
The TyG index is a simple predictor that can well predict left ventricular function and myocardial strain. The combination of TyG index and layer-specific speckle tracking technology is available to identifying the high-risk population of DM in ACS patients.
Decreased Influenza Vaccination Coverage among Chinese Healthcare Workers during the COVID-19 pandemic
Authors: Ma Libing , Han Xuan , Ma Yuan , Yang Yuan , Xu Yunshao , Liu Di , Yang Weizhong , Feng Luzhao 
Published: June 2022

Abstract
Background
Healthcare workers were the priority group for influenza vaccination, however, the vaccination rate among them in China had always been low. This study was conducted to investigate the influenza vaccination status among Chinese healthcare workers (HCWs) during the 2020/2021 and 2021/2022 influenza seasons and analyze the factors driving vaccination.
Methods
We provided Electronic questionnaires to the healthcare workers from January 27, 2022 to February 21, 2022 using the WeChat platform "Breath Circles". Binary logistic regression models were used to analyze the factors associated with vaccination among healthcare workers.
Results
Among the 1697 healthcare workers surveyed, the vaccination coverage during the 2020/2021 and 2021/2022 influenza seasons was 43.67% (741/1697) and 35.36% (600/1697), respectively. Additionally, during the 2020/2021 and 2021/2022 influenza seasons, only 22.69% (385/1697) and 22.10% (358/1697) surveyed healthcare workers reported that their workplaces implemented the free vaccination policy for all employees, respectively.
Conclusions
Free influenza vaccination policy and workplace mandatory vaccination are effective in improving the influenza vaccination coverage in healthcare workers. The Chinese healthcare workers’ influenza vaccination coverage remained low and showed a downward trend after the outbreak of the COVID-19 pandemic. Further effective measures should be taken to improve influenza vaccination coverage.
Grinding worm wear evaluation and its influence of on gear surface topography in continuous generating gear grinding
Authors: Tao Yijie , Li Guolong , Cao Bing , Jiang Lin 
Published: June 2022

Abstract
Due to complex geometry and movement involved in continuous generating gear grinding, the grinding worm wear characterization is different from that in regular grinding processes. Grinding worm wear evaluation with accumulated removed material volume were investigated through wear status evolution experiments. By changing grinding parameters in orthogonal experiments, grinding worm surfaces with various wear status and their resulting gear surface roughness were obtained. The results show that the fractal dimension could be used to roughly quantify grinding worm wear status. A nearly linear relationship was found between the fractal dimension and the removed material volume. Grinding speed, normal stock, feed rate and shifting value were proven to have great influence on grinding worm wear. A significant negative correlation was found between the fractal dimension and surface roughness. However, due to shifting movement, both coarse grinding parameters and finished grinding parameters can affect gear surface. Smaller fractal dimensions were found to result in smoother gear surfaces and vice versa. Based on the result, grinding parameters in continuous generating grinding were recommended. Grinding speed should be as high as possible considering the machine tool capability. Normal stock of 0.02-0.09mm, feed rate of 50-100mm/min, shifting value of 7mm should be adopted in finished grinding.
Phytochemical analysis and beneficial effects of Artemisia absinthium L. essential oil in rat pseudopregnancy model
Authors: Demirel Murside Ayse , Süntar İpek , Çeribaşı Ali Osman , Akça Kevser Taban , Zengin Gökhan 
Published: June 2022

Abstract
Pseudopregnancy is a luteal phase syndrome in which steroids, prolactin inhibitor agents or ovariectomy/ovariohysterectomy are used in the treatment. New medical strategies should be developed because of the serious side effects of current treatment regimens. Several plants and natural compounds are investigated for their modulatory effect on hormonal balance in the treatment of pseudopregnancy. Artemisia absinthium L. (wormwood) is a medicinal plant that belongs to the Asteraceae family, used as an emmenagogue and to induce abortus traditionally. This plant has a regulatory effect on the dopaminergic system. In this study, the therapeutic potential of the A. absinthium essential oil was examined in an experimentally-induced pseudopregnancy model in rats. The pseudopregnancy model was induced by injection of a pregnant mare’s serum gonadotropin and human chorionic gonadotropin to female rats. Essential oil of A. absinthium was orally administered to the rats at 12.5 mg/kg, 25 mg/kg and 50 mg/kg doses once daily for 10 days. Bromocriptine (3 mg/kg/per os) was administered to the reference group animals. Gas Chromatography analysis was conducted on the essential oil to reveal its phytochemical profile. A. absinthium essential oil at 25 mg/kg dose displayed beneficial effects in the pseudopregnancy model in rats. Cis-chrysanthenyl acetate (17.8), sabinyl acetate (11.6%), terpinen-4-ol (6.2%), caryophyllene oxide (5.5%) and (E)-nuciferol (5.5%) were found as the major components in the oil. A. absinthium essential oil rich in cis-chrysanthenyl acetate, sabinyl acetate, terpinen-4-ol, caryophyllene oxide, and (E)-nuciferol should be displayed therapeutic activity against pseudopregnancy.
Leveraging 13 million responses to the Facebook COVID-19 Trends and Impact Survey to examine vaccine hesitancy, vaccination, and mask wearing, January 2021-February 2022
Authors: Nguyen Quynh C. , Yardi Isha , Gutierrez Francia Ximena Marin , Mane Heran , Yue Xiaohe 
Published: June 2022

Abstract
Background: The urgency of the COVID-19 global pandemic called upon the joint efforts from the scientific and private sectors to work together to track vaccine acceptance, prevention behaviors, and symptoms. Methods: Our study utilized individual responses to the Facebook’s COVID-19 Trends and Impact Survey from January 2021 to February 2022 (n=13,426,245) to examine contextual and individual-level predictors of COVID-19 vaccine hesitancy, vaccination, and mask wearing. Adjusted logistic regression models were developed to examine individual and zip code predictors of COVID-19 vaccine hesitancy and vaccination status. Given the COVID vaccine was rolled out in phases in the U.S. we conducted analyses stratified by time, January 2021-May 2021 (Time 1) and June 2021-February 2022 (Time 2). Results: On January 2021 only 9% of Facebook respondents reported receiving the COVID-19 vaccine, and 45% were vaccine hesitant. By February 2022, 80% of respondents were vaccinated and only 18% were vaccine hesitant. Individuals who were older, held higher educational degrees, worked in white collar jobs, wore a mask most of the time or some of the time, and identified as white and Asian had higher COVID-19 vaccination rates and lower vaccine hesitancy across Time 1 and Time 2. COVID vaccinations were lower among essential workers and blue-collar occupations (OR=0.31-0.40) including those in food preparation and serving, construction, installation and repair, transportation, and production in Time 1. In Time 2, these disparities attenuated but were still present (OR-0.36-0.64). For these same occupation groups, vaccine hesitancy was higher (OR=1.88-2.30 in Time 1) and (OR=2.05-2.80 in Time 2). By Time 2, all adults were eligible for the COVID-19 vaccine, but blacks (OR=0.71; 95% CI: 0.70-0.72) and multiracial (OR=0.47; 95% CI: 0.47-0.48) individuals had lower vaccination and higher vaccine hesitancy compared to whites. Conclusions: Associations found in earlier phases of the pandemic were generally found to also be present later in the pandemic, indicating stability in inequities. Additionally, inequities in these important outcomes suggests more work is needed to bridge gaps to ensure that the burden of COVID-19 risk does not disproportionately fall upon subgroups of the population.
Influence of process parameters and robot postures on surface quality in robotic machining
Authors: Xu Peng , Gao Yinghao , Yao Xiling , Ng Ye Han , Liu Kui , Bi Guijun 
Published: June 2022

Abstract
The use of industrial robots for machining large parts has attracted more and more attention. Previous studies have shown that ball-end milling is greatly affected by the process parameters. Besides, robotic machining is also affected by various posture-dependent robot performances. However, these two critical aspects are usually treated separately in many works for studying robotic machining. In this paper, a redundant robotic system consisting of a six-axis industrial robot, a two-axis positioner and a linear track was developed for machining. The combined effects of milling process parameters and robot postures on the machining results were experimentally investigated. Grey relational analysis-based multi-objective optimization was conducted for lower cutting force and better surface quality. A group of process parameters and robot posture was obtained as the optimal combination that generally yields the best milling performance. The results allow to preliminarily determine the main factors that affect the quality of robotic machining.
Surgical management of Lutembacher’s syndrome in congestive cardiac failure
Authors: Yadav Rajeshwar , Pathak Swati , Gupta Shubham K 
Published: June 2022

Abstract
Introduction: Lutembacher’s syndrome is rare clinical entity.In 1916, French physician Rene Lutembacher described his first case of 61 years old woman with a combination of congenital ASD with acquired MS. But he attributed this mitral lesion to congenital mitral stenosis. The definition of this syndrome named after him has undergone many changes since then. The current consensus defines Lutembacher Syndrome (LS) as any combination of ASD (congenital or iatrogenic) and MS (congenital or acquired). The clinical presentation of LS is a result of interplay between size of ASD, severity of MS, pulmonary vascular resistance and RV compliance. Financial constraints also add to the delayed diagnosis and adequate treatment in our part of the world.Here we have discussed a case of LS with severe TR and moderate PAH in congestive cardiac failure which was successfully treated by surgery.Case report: A 42 years old thin built, poorly nourished housewife presented with chest discomfort and fatigue for last 4 years. She was diagnosed with atrial septal defect four years back but could not receive appropriate treatment due to financial constrains. Since last 15 days she had breathlessness even at rest and paroxysmal episodes that interrupted her sleep. Icterus and pedal edema was also present. As we evaluated the patient, her clinical examination could not be completely explained by ASD alone. Soon, our suspicion of LS was confirmed by TTE and the diagnosis of Lutembacher Syndrome with Severe Tricuspid Regurgitation with Moderate PAH was made. As the patient presented to us with atrial fibrillation & heart failure, she was admitted for optimization. The patient was then successfully managed by MVR [#25 SJM, metallic] with pericardial patch closure of ASD with Devaga’s Tricuspid Valve annuloplasty and discharged on postop day 11.Conclusions: Early diagnosis and surgical treatment bears a good prognosis and prolongs survival. If patient is diagnosed at late stage, pulmonary hypertension and heart failure sets in and the outcome becomes poor. Higher cost of the surgical intervention and low socio-economic distribution of the disease in developing country like India should not challenge the patient’s right to receive the standard treatment.
Bryophyte species richness and functional traits in the managed temperate forests are also driven by bedrock and tree species composition
Authors: Kutnar Lado , Kermavnar Janez , Sabovljević Marko S. 
Published: June 2022

Abstract
Questions
Bryophytes represent an important component of forest biodiversity and vegetation, responding to a variety of environmental factors. These include geological conditions with upper soil horizons and tree species composition, which is the result of both natural and anthropogenic factors. The bryophyte species and functional diversity and composition were studied in different temperate forests.
Location
Representative managed forests from lowlands to high mountain areas in Slovenia, Europe.
Methods
Bryophytes growing on a variety of substrates, including terricolous, lignicolous, corticolous and saxicolous species, were identified in 57 ICP-Forests monitoring plots in a wide range of managed forests. Considering data on tree layer composition (broadleaves vs. coniferous), bedrock and soil type (carbonate vs. silicate), all study plots were classified into five groups representing different forest types, including stands dominated by: i) broadleaves on calcareous bedrocks, ii) broadleaves on intermediate bedrocks/soils, iii) broadleaves on siliceous bedrocks, iv) conifers on calcareous bedrocks, and v) conifers on siliceous bedrocks. The species composition and diversity of bryophytes and their functional traits were studied.
Results
Among broadleaves, European beech (Fagus sylvatica) was the dominant tree species in the studied forests, while Norway spruce (Picea abies) was the most common tree species among conifers. The most frequent bryophyte species were Hypnum cupressiforme (present in 91.2% of all plots), Brachytheciastrum velutinum (63.2%) and Polytrichum formosum (61.4%). The mean species richness per plot was 19.4 (minimum: 5, maximum: 36). In the studied plots, tree species composition and bedrock were important drivers in bryophyte species richness and composition. Considerable changes in bryophyte species composition were observed along the tree species composition and edaphic gradient. The bryophyte species richness was significantly higher on calcareous bedrock with very different microhabitats than on siliceous bedrock. The functional diversity and composition of bryophytes were significantly influenced by bedrock and soil, but less by tree species composition.
Conclusions
This study shows that bedrock and tree species composition have a significant effect on bryophyte species, functional traits, and diversity patterns. Tree species composition was also related to past forest management, which could lead to a higher proportion of spruce or other commercial conifers in the small portion of plots. However, the studied forests are mainly managed according to close-to-nature and sustainable principles.