bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cannabidiol Inhibited Reproductive Ability of Zebrafish (Danio Rerio) with Gender-Dependent Manner
Authors: LI LIN , Fan Bei , Kong Zhiqiang , Zhang Yifan , Zhao Mengying , Jesus Simal-Gandara , Wang Fengzhong , LI Minmin 
Published: September 2022

Abstract
Cannabidiol (CBD), a medically active component of hemp, is a popular ingredient in healthcare and personal-care products. The increasing demand for CBD and the legalization of hemp growth may promote chronic exposure of non-target organisms and animals to CBD. In the present study, the reproductive toxicity of CBD was investigated using zebrafish as a model organism. With CBD treatment, parent female zebrafish spawned less with higher natural mortality and malformation rates, showed a decreased gonadosomatic index with an increased percentage of pre-mature oocytes and sperm and had an increased hepatosomatic index. The value of estrogen/testosterone (E2/T) decreased in female zebrafish and increased in male zebrafish. Vitellogenin content was decreased in both female and male zebrafish. Reproductive-related genes were downregulated in the zebrafish brain and liver, whereas esr-α, esr-β, and ar were downregulated in ovaries and upregulated in testicles. Sex hormone synthesis genes were downregulated in ovaries and upregulated in testicles, except for cyp11a, in contrast to the other genes. Apoptosis-related genes were upregulated in the zebrafish brain, gonad, and liver. These results show that CBD might damage the hypothalamus-pituitary-gonad-liver axis function by inducing an apoptotic response, further inhibiting zebrafish reproductive ability in a sex-dependent manner.
Novel 2-hydroxynapthyl functionalized aluminum-based metal-organic framework for fluorescence detection of Zn 2+ in the aqueous medium
Authors: Kaur Manpreet , garg Deepika , Yusuf Mohamad , Malik Ashok Kumar 
Published: September 2022

Abstract
A new aluminum-based metal-organic framework (MOF), namelyMIL-53-HNA, was synthesized using low-cost Schiff base linker, 2-(2-hydroxynapthyl-1-imine)terephthalic acid (coded as H2HNA). Because of an excellent fluorescent features of this synthesized MOF, we decided to test its suitability for detecting heavy metal ions in aqueous solution. It is interesting to note that the MIL-53-HNA chemosensor could detect Zn2+ ions in water via turn-on response with good sensitivity and selectivity without being interferedfrom diverse metal ions including Na+, Cd2+, Cu2+, Ni2+, Al3+, Pb2+, Co2+, and Fe3+. The selectivity of this sensortowards Zn2+ ions in aqueous solution could be explained through preferential complexation of these ions via free hydroxyl and imine groups present inside its pore cages. This selective complexation suppressed the photo-induced electron-transfer (PET) process from imine (-CH=N-) double bond to the naphthalene group. This suppression of PET process restored the fluorescence of the naphthalene group in the Zn2+treated MIL-53-HNA chemosensor which ultimatelyled to enhancement of itsfluorescence intensity. Theoreticalcalculations have also been done to provide a thorough explanation of thisturn-on mechanistic response of MIL-53-HNA towards Zn2+ions. Additionally, this sensor showed extremely low limit of detection (LOD), 6.8 µM, demonstrated its exceptional Zn2+ detection capabilities. Low cost, excellent stability, sensitivity, and selectivity are the most promising characteristics of this synthesized chemosensor which make it suitable for wastewater treatment.
How to Rejuvenate Traditional Markets
Authors: Andriana Denny , Smith Julia A , Reid Gavin C 
Published: September 2022

Abstract

We propose a research agenda for exploring the efficacy of indigenous markets, with pasar in Indonesia as an example. The piecemeal application of policies across multiple provinces has been variable in its success. Indonesia offers a rich and varied palette of research projects, aimed at exploring the unique marketplace phenomenon of pasar. Our initial finding is that there is a considerable advantage of Jakarta over Bandung pasar, in terms of both tangible and intangible measures of quality.Article Type: Research Corner
Medication adherence and cognitive performance in schizophrenia-spectrum and bipolar disorder: results from the PsyCourse Study
Authors: Senner Fanny , Hiendl Lena , Bengesser Susanne , Adorjan Kristina , Anghelescu Ion-George , Baune Bernhard , Budde Monika , Dannlowski Udo , Dietrich Detlef , Falkai Peter , Fallgatter Andreas , Hasan Alkomiet , Heilbronner Maria , Jäger Markus , Juckel Georg , Kalman Janos , Konrad Carsten , Kohshour Mojtaba Oraki , Papiol Sergi , Reich-Erkelenz Daniela , Reimer Jens , Schaupp Sabrina , Schmauß Max , Senner Simon , Spitzer Carsten , Vogl Thomas , Zimmermann Jörg , Heilbronner Urs , Schulte Eva , Schulze Thomas G. , Reininghaus Eva , Kirchner Sophie-Kathrin , Dalkner Nina 
Published: September 2022

Abstract
Existing guidelines recommend psychopharmacological treatment for the management of schizophrenia and bipolar disorder as part of holistic treatment concepts. About half of patients do not take their medication regularly, although treatment adherence can prevent exacerbations and re-hospitalizations. To date, the relationship of medication adherence and cognitive performance is understudied. Therefore, this study investigated the relationship between medication adherence and cognitive performance by analyzing the data of 862 participants with schizophrenia-spectrum and bipolar disorders (mean [SD] age, 41.9 [12.48] years; 44.8% female) from a multicenter study (PsyCourse Study). Z-scores for three cognitive domains were calculated, global functioning was measured with the Global Assessment of Functioning Scale, and adherence was assessed by a self-rating questionnaire. We evaluated four multiple linear regression models and built three clusters with hierarchical cluster analyses. Higher adherence behavior (p < 0.001) was associated with better global functioning but showed no impact on the cognitive domains learning and memory, executive function, and psychomotor speed. The hierarchical cluster analysis resulted in three clusters with different cognitive performance, but patients in all clusters showed similar adherence behavior. The study identified cognitive subgroups independent of diagnoses, but no differences were found in the adherence behavior of the patients in these new clusters. In summary, medication adherence was associated with global but not cognitive functioning in patients with schizophrenia-spectrum and bipolar disorders. In both diagnostic groups, cognitive function might be influenced by various factors but not by medication adherence.
Improvements in histological technique for the ecotoxicological assessment using small biological samples
Authors: SANTANA LIGIA , Damasceno Évila P. , Loureiro Susana , Soares Amadeu M.V.M. , Pousão-Ferreira Pedro , Abessa Denis M. S. , Martins Roberto , Pavlaki Maria D. 
Published: September 2022

Abstract

Histological techniques consist of traditional and very important tools for a better understanding of cellular morphology and physiology in ecotoxicological studies. Despite bioassays generally recommending the use of small test organisms, based on some advantages as their low maintenance costs and large replicates’ number, the histological processing of small organisms is not commonly used due to demanding laboratorial handling. The present study proposes an accessible protocol for a histological method in fish larvae with a maximum length of 8 mm, as well as the use of histopathological biomarkers on Senegal sole larvae for ecotoxicological testing. Eight-day old larvae of Solea senegalensis obtained from breeders' natural spawns in cultivation conditions were submitted to histological processing by an adjusted protocol comprising fixation, agarose array pre-embedding, paraffin embedding, slides preparation, and image analysis by light optical microscope coupled to a digital camera. Low-cost and easy-to-use alternatives were applied in the technique execution. The histological steps were detailed and the multiple tissues and cellular structures of the S. senegalensis larvae were described and discussed. This can be considered a valuable background information for ecotoxicological studies where changes in cell morphology and physiology are expected.
Adaptation of a psycho-educative group programme to improve coping in dementia caregiving: a feasibility study with mixed-methods
Authors: Pihet Sandrine , Clément Marie , Terrapon Eugenie , Kipfer Stephanie 
Published: September 2022

Abstract
Background
As the number of people living with dementia rapidly increases worldwide, the support provided by their informal caregivers remains key to the sustainability of most healthcare systems, this voluntary contribution representing 40% of the costs of dementia worldwide. Informal caregiving in dementia, however, is linked to long periods of chronic stress with frequent and serious negative consequences on the health and quality of life of the caregiver. A psycho-educative group intervention focusing on coping with the daily stress of dementia caregiving (“Learning to feel better… to help better”), developed in French-speaking Canada and showing broad effects on quality of life, was selected with the aim of 1) adapting it to a new cultural context (French-speaking Switzerland) based on identified facilitators and barriers, using a participative approach; and 2) conducting a feasibility study to evaluate whether the adapted programme showed similar or improved feasibility and effects compared to the original Canadian programme.
Methods
A mixed-methods concurrent nested design was used to evaluate the feasibility and the effects on five quantitative core outcomes. Additional qualitative data helped document in depth the acceptability and impact of the intervention.
Results
We shortened the programme from 30 to 21 hours in total, which resulted in increased accessibility, in terms of facilitated recruitment of participants and inclusion of a broader range of informal caregivers. There were significant reductions in subjective burden (effect size: d=-0.32) and psychological distress (d=-0.48), as well as decreases in the stress reactions of informal caregivers related to the behaviour problems of the persons with dementia (d=-0.57). The qualitative results emphasized the usefulness of providing informal caregivers with structured procedures for efficiently tackling everyday challenges, and of enabling learning through a variety of channels and activities.
Conclusions
Substantial improvements are associated with this 21-hour group intervention, organised in 7 sessions of 3 hours each, focused on learning more efficient strategies to cope with the daily stress of dementia caregiving. This intervention empowered informal caregivers to master their daily challenges with more confidence, satisfaction and calm.
Trial registration:
ISRCTN13512408 (registration date 17.05.2021, retrospectively registered).
Wetland Ecosystem: Plant Species Diversity, Services, Degradation Drivers, and Community Perception in Sinana District, Oromia Region, Southeast Ethiopia
Authors: Abdulmalik Kemalo , Ingale Lalit , Mulatu Kassahun 
Published: September 2022

Abstract

Wetlands are a vital source of biodiversity and ecosystem services. The study investigated the plant species diversity and assesses the perception of the area people on ecosystem services, and drivers of wetland degradation in Sinana district, Southeast Ethiopia. Vegetation inventory, household survey, focused group discussion, and key informant interviews were employed to gather information. A complete of 45 sample plots laid along transacts were inventoried. A plot size of 5m x 5m (25 m2) and 1m x 1m (1m2) nested within the major plot was used for shrubs and herbaceous respectively. A total of 137 households were surveyed to collect socioeconomic data. The study identified 20 plant species belonging to 14 families. Family Cyperaceae was dominant within the studied wetland. The Shannon diversity (H = 1.15) indicates the wetland has low vegetation diversity with uneven distribution (E = 0.385) of vegetation. A total of 20 ecosystem services thought to be under-provisioning, regulating, and cultural services were identified. According to plaintiffs, major provision services are grazing of livestock (77.4%), irrigation (76.6%), and harvesting of grass for fodder (68.6%). Important drivers of wetland degradation are shortage of cropland (70.8%), lack of awareness (69.3%), upland land degradation (65.7%), and increasing population (62%). The main driver, shortage of cropland was the key driver followed by a lack of awareness and upland land degradation. Therefore, the result heightened that the studied wetland is under serious degradation due to high human pressure associated with population growth and climate change. Thus, an appropriate wetland management strategy has to be designed.
Convective Heat and Mass Transfer Rate on 3D Williamson Nanofluid Flow via Linear Stretching Sheet with Thermal Radiation and Heat Absorption
Authors: Jagadeesh Shiva , Reddy M. Chenna Krishna 
Published: September 2022

Abstract
A mathematical analysis is communicated to the thermal radiative and heat absorption effects on 3D MHD Williamson nanoliquid motion via stretching sheet. The convective heat and mass boundary conditions are taken in sheet when liquid is motion. The suitable similarity transformations, non-dimensionless has been utilized for reduce basic governing PDE’s into coupled system of ODE’s, also compute numerical solutions with the help of 4th order R-K-F procedure with shooting technique in MATLAB programming. The various physical parameters analysed numerically on \(f'(\eta )\)(“Velocity profile”),\(\operatorname{Re} _{x}^{{ - 1/2}}N{u_x}\) (“Heat Transfer Rate”) and \(\operatorname{Re} _{x}^{{ - 1/2}}Sh\) (“Mass Transfer Rate”). We noticed that, the \({\operatorname{Re} _x}^{{1/2}}{C_{fx}}\)(“Skin friction coefficient along \({x^*}\)-axis”), \({\operatorname{Re} _x}^{{1/2}}{C_{fy}}\)(“Skin friction coefficient along \({y^*}\)-axis”) and also compared with precious results and present results for various conditions. Finally, in the present result is good invention of the previous results.
Carrier Phase Bias Correction for GNSS Space-Time Array Processing Using Time-Delay Data
Authors: Yuchen Xie , Chen Feiqiang , Huang Long , Liu Zhe , Wang Feixue 
Published: September 2022

Abstract
Due to low transmitting power, GNSS signals are so vulnerable that can be easily jammed by accidental or malicious interference. The space-time array processing (STAP) technology is the most effective way for anti-jamming, but the undesired bias would be introduced by STAP leading to distortion of signals. To solve this problem, traditional methods usually calibrate antennas together with applying distortionless algorithms. However, the calibrating is burdensome and cannot be batched, while most of distortionless algorithms require the information of signal direction, so these methods are not applicable in general array receivers. This paper proposes the time-delay carrier phase bias estimation (TD-CPBE) algorithm for STAP bias correction, which does not need antenna calibration or signal direction information. TD-CPBE locates changing moments of jamming, estimates the STAP introduced carrier phase bias by open-loop tracking of time-delay data, and corrects it by phase shift in tracking procedure. The simulation results show that TD-CPBE can effectively correct STAP carrier phase bias with residual error less than 3°, which is close to that of traditional distortionless algorithm, and the open-sky experiment further verifies the proposed algorithm. Since TD-CPBE requires much less prior information, it is a very effective and applicable method for STAP carrier phase bias correction.
Relationships Between Training Load, Maturity offset, Muscle Soreness and Fatigue Status in Elite-level Young Soccer Players: A Competition Season Study
Authors: Nobari Hadi , Eken Özgür , Kamiş Okan , Oliveira Rafael , Aquino Rodrigo 
Published: September 2022

Abstract
Background: This study aimed to compare training load parameters, delayed onset muscle soreness (DOMS), and fatigue status between season periods (1st and 2ndhalves) in U14 soccer players and to analyze the relationships between training load parameters based on season periods (1st and 2nd half) with maturity offset, DOMS, and fatigue status in under-14 (U14) young elite soccer players. Additionally, it was intended to analyze if fatigue and DOMS could explain training load parameters across the season.
Methods: Twenty U14 players that competed in the national league participated in this study. The players were monitored during the whole season (26 weeks), and evaluations were carried out once the season containing the competitive matches had concluded. Anthropometric and body composition parameters, as well as the maturity status of each player, were utilized to compute each player's age at peak height velocity (PHV). Players reported their levels of DOMS and fatigue status using Hooper index questionnaires. Internal load was monitored using the rating of perceived exertion (RPE). Acute weekly internal load (AW), chronic weekly internal load (CW), acute: chronic workload ratio (ACWR), training monotony (TM), and training strain (TS) were also obtained.
Results: The main results showed that TM was higher in the 2ndhalf while CW, AW and DOMS were higher in the 1st half of the season. Moreover, there were a negative correlation between PHV and maturity; a positive correlation between PHV and TS (2nd half of the season); a positive correlation between maturity and ACWLR (1st half of the season); a negative correlation between maturity and TS (2ns half of the season); a negative correlation between TM-total and maturity.
Conclusion: In conclusion, variations in well-being status cannot be explained for variations in internal training loads in elite U14 soccer players. In addition, internal training load indices during the first half of the competitive season can promote a fundamental base to progression loads during the second period of the competitive season.
Scalable Image Compression Algorithms with Small and Fixed- Size Memory
Authors: Al-Janabi Ali Kadhim , Harbi Yahya J. , Hassan Mohammed Falih 
Published: September 2022

Abstract

The SPIHT algorithm is characterized by low computational complexity, good performance, and the production of an embedded bitstream that can be decoded at several bit-rates with image quality enhancement as more bits are received. However, it suffers from the enormous computer memory consumption due to utilizing linked lists of size of about 2–3 times the image size to save the coordinates of the image pixels and the generated sets. In additions, it does not exploit the multi-resolution feature of the wavelet transform to produce a resolution scalable bitstream by which the image can be decoded at numerous resolutions (sizes). The Single List SPIHT (SLS) algorithm resolved the high memory problem of SPIHT by using only one list of fixed size equals to just 1/4 the image size, and an average of 2.25 bits/pixel. This paper introduces two new algorithms that are based on SLS. The first algorithm modifies SLS to reduce its complexity and improve its performance. The second algorithm, which is the major contribution of the work, upgrades the modified SLS to produce a bitstream that is both quality and resolution scalable (highly scalable). As such, the algorithm is very suitable for the modern heterogeneous nature of the Internet users to satisfy their different capabilities and desires in terms of image quality and resolution.
Non-linear dynamics of system with combined rolling-sliding contact and clearance
Authors: Suryawanshi Sarabh , Sundar Sriram 
Published: September 2022

Abstract
Rolling-sliding contacts are found in a variety of systems, such as gears, drum brakes, and tire-pavements. Such systems inherently have multiple non-linearities such as kinematic, contact, and friction non-linearities. Further, most of these systems have clearance between components which causes excessive vibration and noise. The combination of clearance with other non-linearities makes the system dynamically interesting. It is important to understand the dynamic behaviour of such systems under various operating conditions. Hence, this article focuses on theoretically investigating the transient & steady-state responses of a
cam-follower system with rolling-sliding contact and clearance as an exemplary case. A contact mechanics-based model for the same has been developed for this purpose. The transient behaviour of the system is examined based on energy and time-varying frequency contents. The domain of attractors, frequency response plots, and phase portraits are deployed to analyze the effect of initial conditions and excitation speed on the steady-state behaviour, quantitatively and qualitatively. The steady-state solutions were classified into various branches based on periodicity and phase portraits. In addition, parametric analyses of the effects of loading, damping, and friction on the response have been conducted. Finally, the system is examined for start-up and shut-down characteristics with a constant rate of change in excitation frequency.
Seroprevalence and associated risk factors of Toxoplasma gondii in goats and sheep in the Khomas region of Namibia
Authors: Samkange Alaster , Chitanga Simbarashe , Tjipura-Zaire Georgina , Mutjavikua Vimanuka Gibs , Smith Jan Wilhelm , Neves Luis , Matjila Tshepo 
Published: September 2022

Abstract
This study aimed to determine the seroprevalence levels of T. gondii in small ruminants (goats and sheep) and the associated risk factors in the Khomas region of Namibia. A total of 299 and 345 sheep and goat sera, respectively, were collected from 22 farming establishments. An IDEXX Toxotest Ab®, a commercial ELISA kit, was used to test for IgG antibodies to T.gondii. Overall, 3.68% (11/299) of the sheep sera were positive, and 61.54% (8/13) of the sheep flocks tested had at least one positive animal. Only 0.29% (1/345) of the goat sera were positive, and only one of the 19 goat flocks had at least one positive animal giving a herd-level prevalence of 5.26%. Sheep flocks had significantly greater animal-level and flock-level prevalences than goats (p < 0.05) and were 13.14 times more likely to be seropositive (OR = 13.14; CI 95%: 1.686-102.382) than goat flocks. A questionnaire was also administered to identify any putative risk factors associated with seropositive cases. Eight risk factors were evaluated, including the total number of goats, total number of sheep, farm size, average rainfall, level of Feliformia, history of abortions and the presence of domesticated cats and strays. Seropositivity to T. gondii was positively associated with the total number of sheep at the farming establishment, history of abortions and farm size (p < 0.05), but not goats. The study concluded that sheep were probably more susceptible to toxoplasmosis than goats and that the T. gondii seroprevalence level in the Khomas region was very low compared to other countries.