bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nilai-Nilai Moral dalam Kumpulan Puisi “Senja Di Batas Kata” Karya Dimas Arika Miharja
Authors: Maiza Suci , Rifki Ansanul 
Published: July 2022

This study aimed to describe the moral values of poetry ”Senja di Batas Kata “by Dimas Arika Miharja. The Theory supporting use Nurgiantoro (2019) Pradopo (2005). The study used the qualitative approach with a descriptive method with content analysis. The data of this reseach are in the form of words, phrases, or sentence which are physcal and mental elements of poetry. These elements are used to find moral values in poetry. The research data was in the form of text which contained the moral values of the poetry ”Senja di Batas Kata” by Dimas Arika Miharja. The results showed that the supporting structures of the ”Senja di Batas Kata” poetry were existed, namely thephysical and mental structures. Based on the analysis of the physical and mental elements, it found that the moral values of poetry “Senja Di Batas Kata”by Dimas Arika were related to the personal character building, such as (1) dare to defend the truth, (2) be aware and careful to all events, (3) virtuous, Moral values related to social character building were (1) love each other, (2)advice each other and cooperate. There are three moral values of human relations with God, (1) faith, (2)worship and seeking God and (3)remembering death.
Female Swearing on WhatsApp Communications: A Sociolinguistics Perspective
Authors: Kurniawanti Fahrisal , Damanhuri Adam 
Published: July 2022

Traditionally, swearing was considered a taboo subject. However, in today’s era swearing has become a common thing. It is practiced not only by men but women also practice it. To avoid social impoliteness, it is practiced in various ways, purposes, and languages based on the context. This research analyzed the types and functions of English swearing used by females on WhatsApp seen from a sociolinguistics perspective. Ljung (2011) and Vingerhoets & Bylsma (2013)’s theories were applied in this research. Observations were conducted through WhatsApp stories in gaining eight written utterances data and virtual interviews were conducted by eight participants in gaining the functions of swearing data. The results show four types of swear words covered the use of swearing, namely: religious theme, scatological theme, sexual activities theme, and mother/family theme. Each of these themes has different functions depending on the context of utterances. Other results indicate that females function English swearing in intra-individual and inter-individual. Intra-individual functions lead to show anger, frustration, and annoyance. Inter-individual functions lead to insulting others and showing solidarity. These functions were triggered by positive emotions (excitement and chill out with friends) and negative emotions (anger, frustration, and annoyance). Mostly Females swear triggered by negative emotions.
Surgical Specifics of Lower Limb Superficial Thrombophlebitis Combined with Undifferentiated Connective Tissue Disease
Authors: Timerbulatov M. V. , Murasov T. M. , Murasov A. M. 
Published: July 2022

Background. Superficial thrombophlebitis of lower extremities is among the most frequent acute vascular pathologies. Concomitant undifferentiated connective tissue dysplasia exerts specific changes in its clinical course.Aim: A study of the specific dynamics of acute lower limb superficial thrombophlebitis (ST) and its surgical treatment in patients with undifferentiated connective tissue dysplasia (UCTD).Materials and methods. The case histories, surgery reports and follow-up examinations of patients treated at the Vascular Surgery Unit during 2012–2020 were analysed. A total of 86 patients had signs of UCTD and underwent classical crossectomy of the great saphenous vein (Troyanov operation).Results and discussion. Duplex ultrasound of lower limb veins in 34 (39.53 %) patients revealed a discrepancy between the upper localisation of thrombotic masses in the great saphenous lumen and the external boundary registered for clinical manifestations, hyperaemia and tissue thickening. In 69 (80.23 %) patients, four or more phenotypic UCTD markers were exposed. In 74 (86.05 %) cases, a classical Babcock phlebectomy was performed as a next stage within one year after an acute thrombophlebitis attack had subsided. Of 12 (13.95 %) patients not having had a second-stage phlebectomy within one year: 4 people had UCTD signs — they refused surgery due to absent significant complaints or marked saphenous reflux; 3 had a deep vein thrombosis episode; 5 had no saphenous reflux of lower extremities in ultrasound examination.Conclusion. The registration of phenotypic signs of undifferentiated connective tissue dysplasia is recommended in choosing a surgical tactic to treat acute ascending thrombophlebitis of lower limb saphenous veins.
Analisis kekerasan dan keausan bearing pada pesawat Cessna Grand Carravan 208B
Authors: Septiyanto Muhammad Abdul Rafiq , Suroso Indreswari , Utami Noviana 
Published: July 2022

Bearing is a surface component that protects two parts that rub against each other. Bearings have several components including inner rings, roll bearings and supports. Bearings will experience weariness when used continuously, so the purpose of this study is to determine the level of hardness and wear of each bearing component of the Cessna Grand Caravan 208B aircraft. Hardness testing is carried out by vickers method and test sampling is carried out at three different points in each specimen. Wear testing uses the Ogoshimethod and test sampling is performed at three different points in each specimen. The results of this study concluded that vickers hardness testing received the highest hardness score on the roll with an average value of 739.7 VHN, the second highest hardness in the inner ring had an average hardness value of 695.1 VHN, and the lowest hardness in the buffer section had an average hardness value of 110.2 VHN. The wear test results get the highest value on the support section which is 0.00273 mm³ / kg.m, the second highest wear on the inner ring is 0.00133 mm³ / kg.m, and the lowest wear value on the roll is 0.00056 mm³ / kg.m.
Bioremediation of Pb and Cd contaminated soil using microorganism
Authors: Wulandari Andriyani Dea , Meitiniarti Vincentia Irene 
Published: July 2022

The increase in industrial waste, especially those containing Pb and Cd, which is discharged into the environment results in more polluted environment conditions. Polluted enviornment is very dangerous for the survival of living things. This technique use living things to reduce environmental pollution, making it safe for living things. Bioremediation can be carried out by in-situ and ex-situ methods with several bioremediation mechanisms, including biosorption, bioaccumulation, bioleaching, and bioprecipitation. The use ex-situ techniques in bioremediation is easier to do, especially if it is carried out to remediate soils under controlled conditions in the laboratory.
Irrigation Frequency and Volume has Little Influence on Phytophthora Root Rot in Container-grown Rhododendron
Authors: Weiland Jerry E. , Scagel Carolyn. F. , Grünwald Niklaus J. , Davis E. Anne , Beck Bryan R. , Mitchell Jesse N. 
Published: July 2022

Abstract
We evaluated whether reducing irrigation frequency and volume alters the ability of Phytophthora plurivora and P. cinnamomi to cause root rot on rhododendron grown in a noninfested potting medium or media infested with 1 or 100 propagules per gram (ppg) of pathogen. Plants were irrigated to maintain a substrate moisture of &gt;70% container capacity (1.0X), one-half volume of 1.0X (0.5X), or two times the volume of 1.0X at each irrigation event for one week, followed by no irrigation, until soil moisture reached &lt;50% container capacity. Aboveground disease symptoms (chlorosis, stomatal conductance, wilting, and plant death) were evaluated weekly and root rot, pathogen presence, plant biomass, and nutrient uptake were measured at the end of each trial. Both pathogens generally caused mild disease at 1 ppg and severe disease at 100 ppg. Reducing irrigation did little to lessen disease caused by either pathogen once infection had occurred. Instead, severe root infection often led to increased soil moisture and root rot across all irrigation treatments as roots became progressively compromised in their ability to take up water. Results show that reducing irrigation after infection has occurred is unlikely to effectively control root rot.
Species used in this study: Phytophthora species (Phytophthora cinnamomi Rands; Phytophthora plurivora T. Jung and T.I. Burgess); rhododendron, Rhododendron catawbiense Michx. ‘Album', ‘Roseum Elegans', and ‘Roseum Pink'.
An Analysis of the Quality of Compost Produced from Vermicomposting Fresh Cut Flower Waste
Authors: Etheredge Coleman L. , Waliczek Tina M. 
Published: July 2022

Abstract
Higher levels of pesticide applications are used when growing cut flowers when compared to other crops such as tomatoes, lettuce, and rice, much of the floriculture industry production occurs in developing countries where less environmental regulations may be in place compared to those in the United States. Therefore, special consideration should be given to cut flower disposal from floral shops due to the potential excessive leaching of pesticides into land and waterways. Most retail florists in the industry dispose of their floral waste into municipal dumpsters. There are an estimated 13,200 retail flower shop locations in the United States, comprised of single location and multiple location companies. While the United States Department of Agriculture (USDA) has stringent guidelines to prevent the importation of pests and plant diseases, there are no regulations on the disposal of spent floral crops that may contain residues of pesticides or other chemicals. Vermicomposting is a method of composting used for pollution abatement while having the added benefit of acting as an alternative waste management method to traditional landfill dumping. The castings produced are a valuable commodity for agricultural, horticultural, and related industries. The main objective of this research was to analyze the quality of compost produced from vermicomposting fresh cut floral waste. Analysis of results was based on the U.S. Composting Council's Tests Methods for the Examination of Composting and Compost used by the U.S. Composting Council's Seal of Testing Approval (STA) program. When compared to STA standards, pH, soluble salts, organic matter, total nitrogen, carbon, carbon-to-nitrogen, bioassay, and respirometry all were found to be within normal ranges for compost sold in the horticulture industry. Chemical analysis found the level of arsenic, cadmium, copper, lead, mercury, molybdenum, nickel, selenium, zinc all to be well below set industry standards. Additionally, the vermicompost was lab tested for 23 herbicides and insecticides. Of those, one herbicide (clopyralid) and two insecticides (clofentezine and lufenuron) were found in the sample in trace amounts, and well below Environmental Protection Agency (EPA) set industry standards for acceptable trace amount in U.S. products. Results indicated floral waste collected from retail flower shops can be incorporated into a vermicomposting system to create a quality compost suitable for use in the horticulture industry.
Novel subcutaneous cytarabine infusion with the Omnipod system in dogs with meningoencephalomyelitis of unknown etiology
Authors: Mancini Shelby L. , Early Peter J. , Slater Bailey M. , Olby Natasha J. , Mariani Christopher L. , Munana Karen R. , Woelfel Christian W. , Schacher Jordan A. , Zhong Li , Messenger Kristen M. 
Published: July 2022

Abstract

OBJECTIVE
To investigate the feasibility and pharmacokinetics of cytarabine delivery as a subcutaneous continuous-rate infusion with the Omnipod system.

ANIMALS
6 client-owned dogs diagnosed with meningoencephalomyelitis of unknown etiology were enrolled through the North Carolina State University Veterinary Hospital.

PROCEDURES
Cytarabine was delivered at a rate of 50 mg/m2/hour as an SC continuous-rate infusion over 8 hours using the Omnipod system. Plasma samples were collected at 0, 4, 6, 8, 10, 12, and 14 hours after initiation of the infusion. Plasma cytarabine concentrations were measured by high-pressure liquid chromatography. A nonlinear mixed-effects approach generated population pharmacokinetic parameter estimates.

RESULTS
The mean peak plasma concentration (Cmax) was 7,510 ng/mL (range, 5,040 to 9,690 ng/mL; SD, 1,912.41 ng/mL), average time to Cmax was 7 hours (range, 4 to 8 hours; SD, 1.67 hours), terminal half-life was 1.13 hours (SD, 0.29 hour), and the mean area under the curve was 52,996.82 hours X μg/mL (range, 35,963.67 to 71,848.37 hours X μg/mL; SD, 12,960.90 hours X μg/mL). Cmax concentrations for all dogs were more than 1,000 ng/mL (1.0 μg/mL) at the 4-, 6-, 8-, and 10-hour time points.

CLINICAL RELEVANCE
An SC continuous-rate infusion of cytarabine via the Omnipod system is feasible in dogs and was able to achieve a steady-state concentration of more than 1 μg/mL 4 to 10 hours postinitiation of cytarabine and a Cmax of 7,510 ng/mL (range, 5,040 to 9,690 ng/mL; SD, 1,912.41 ng/mL). These are comparable to values reported previously with IV continuous-rate infusion administration in healthy research Beagles and dogs with meningoencephalomyelitis of unknown etiology.
A Study on Image Processing Using Artificial Neural Networks in Civil Engineering
Authors: Andon Alexandrina-Elena , Covatariu Gabriela 
Published: July 2022

Abstract
For the last five years, image processing using artificial neural networks (ANN) got several researchers interested in the field of Civil Engineering. As the artificial neural network, which consists of several neurons may not be able to extract features from the image due to the required computing power, the Convolutional Neural Network (CNN) was created. CNN is a machine learning algorithm that uses the image as input, attributing the importance of different aspects (objects in the image) to allow their differentiation. The results recorded in Civil Engineering domain show a real success.
Capsanthin induces death in human prostate cancer cell lines by inducing DNA damage
Authors: Eraslan Ersen , Erden Yavuz , Oruc Sinem , Bircan Burak , Gunay Sevilay 
Published: July 2022

Abstract
There is a relationship between a person’s diet and the development and prevention of some cancers. Carotenoids are found as various natural pigments in many fruits and vegetables. Studies on carotenoids and their potential roles in carcinogenesis are increasing in importance day by day. In this study, we aimed to determine the cytotoxic and genotoxic effects of capsanthin, a carotenoid compound, in human prostate cancer cell lines.
After different concentrations of capsanthin were applied to human prostate cancer cell lines (LNCaP and PC-3), the effects of the compound on cell viability were determined by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) test. The single-cell gel electrophoresis (Comet) assay was then used to reveal the genotoxic effects of probable cytotoxic dosages on cell DNA. After the treatments, apoptotic cell death levels were determined by Tunel staining. At high concentrations, capsanthin dramatically reduced PC-3 and LNCaP cell viability (p<0.05). In addition, capsanthin caused DNA damage and apoptotic cell death in the prostate cancer cells. The results show that capsanthin reduces cell viability by causing genotoxicity in prostate cancer cells.
A Comprehensive Assessment of The Eight Vital Signs
Authors: Draves J , Tekiner H , Yale ES , Mazza JJ , Yale SH 
Published: July 2022

Abstract
The term “vital sign” has been assigned to various phenomena with the presumptive intent to emphasize their importance in health care resulting in the emergence of eight vital signs with multiple designations and overlapping terms. This review developed a case definition for vital signs and identified and described the fifth through eighth vital signs. PubMed/Medline, Google and biographical databases were searched using the individual Medical Subject Headings (MeSH) terms, vital sign and fifth, vital sign and sixth, vital sign and seventh, and vital sign eighth. The search was limited to human clinical studies written in English literature from 1957 up until November 30, 2021. Excluded were articles containing the term vital sign if used alone without the qualifier fifth, sixth, seventh, or eighth or about temperature, blood pressure, pulse, and respiratory rate. One hundred ninety-six articles (122 for the fifth vital sign, 71 for the sixth vital sign, two for the seventh vital sign, and one for the eighth vital sign) constituted the final dataset. The vital signs consisted of 35 terms, classified into 17 categories compromising 186 unique papers for each primary authored article with redundant numbered vital signs for glucose, weight, body mass index, and medication compliance. Eleven terms have been named the fifth vital sign, 25 the sixth vital sign, three the seventh, and one as the eighth vital sign. There are four time-honored vital signs based on the case definition, and they represent an objective bedside measurement obtained noninvasively that is essential for life. Based on this case definition, pulse oximetry qualifies as the fifth while end-tidal CO2 and cardiac output as the sixth. Thus, these terms have been misappropriated 31 times. Although important to emphasize in patient care, the remainder are not vital signs and should not be construed in this manner.
Mucormycosis in COVID-19 patients with uncontrolled diabetes – the lethal triangle
Authors: Neagu Mihaela , Badea Carmen , Tanase Ionut 
Published: July 2022

Abstract

BACKGROUND. Coronavirus disease 2019 (COVID-19) is one of the main global health problems of the twenty-first century, with more than one-hundred million people infected and more than two million deaths. The immunosuppression caused by SARS-CoV-2 infection along with steroidal treatment, hyperglycaemia and elevated ferritin levels creates the perfect environment for opportunistic infections such as mucormycosis. COVID-19-associated mucormycosis carries a high mortality rate. Therefore, in addition to antifungal therapy and aggressive surgical debridement of necrotic tissue, strategies to improve glycaemic index is the key factor in order to obtain a favourable outcome.

MATERIAL AND METHODS. For the purpose of this article, the PubMed databases were searched using MeSH descriptors and the Boolean operator “AND” for the terms “rhinosinusal” and “mucormycosis” and “diabetes”, between February 2019 – December 2021. Clinical characteristics, therapy and outcome data were gathered and compared to what has previously been reported in the literature. Also, we report the case of a 68-year-old patient with uncontrolled type 2 diabetes mellitus, who developed mucormycosis during post-COVID period, to underline the need of early detection of this potentially deadly fungal illness.

RESULTS. The clinical and imaging evaluation revealed no evidence of disease recurrence, at one- and two-months’ follow-ups.

CONCLUSION. In this context, we would like to emphasize the importance of a high index of suspicion for mucormycosis in patients with COVID-19 infection, with pre-existing medical disorders, presenting with rhino-orbital or rhino-cerebral symptomatology.
Carbapenem resistance determinants in Klebsiella pneumoniae strains isolated from blood cultures-comparative analysis of molecular and phenotypic methods
Authors: Tompa Manuela , Iancu Mihaela , Pandrea Stanca L. , Grigorescu Mircea D. , Ciontea Monica I. , Tompa Ronald , Pandrea Stanca M. , Junie Lia M. 
Published: July 2022

Abstract

Introduction: This study provides data on carbapenemases identified in carbapenem-resistant Klebsiella pneumoniae (CR-KP) isolated from blood-cultures by the multiplex molecular method.

Material and method: Between October 2016 and September 2017, 47 non-duplicate Klebsiella pneumoniae (KP) were isolated from blood cultures, from hospitalized patients in the Regional Institute of Gastroenterology and Hepathology, Cluj-Napoca, Romania. Identification and antimicrobial susceptibility tests (AST) were performed by Vitek 2 Compact. The combination disks test (CDT) was used for phenotypic analysis and the LightCycler® Multiplex DNA assay was used to detect and identify the carbapenemases by the LightCycler®z 480 Instrument. The following targets were chosen: blaKPC, blaNDM, blaGES, blaIMP and blaOXA-48 genes and the Cobas® 4800 software variant 2.2.0 was used for the results interpretation.

Results: Taking into consideration the meropenem minimum inhibitory concentration (MIC), 29 KP were susceptible and 18 were not-susceptible (MIC≥0.5 µg ml-1). In the CR-KP group, the CDT identified OXA-48 (10/18) and KPC (7/18) producers. One isolate showed a noninterpretable profile. The multiplex molecular analyses confirmed the carbapenemases production as: 9 CR-KP were KPC and OXA-48 co-producers, 8 were OXA-48 and one was KPC producing strains. In CR-KP group, we found a significant correlation between the CDT and RT-PCR tests results, concerning KPC (p = 0.671). Eight phenotypic results were confirmed by molecular Light-Cycler® Multiplex DNA assay. For CR-KP co-producers (KPC and OXA-48), the CDT could indicate only one carbapenem-hydrolyzing enzyme.

Conclusion: This study highlights the CR-KP co-producers (OXA-48 and KPC). OXA-48-like is more frequently encountered in our area than other carbapenemases.
SPP1 is a biomarker of cervical cancer prognosis and involved in immune infiltration
Authors: Guo Qian , He Wei , Nie Dan , Li Wuzhi , Zhan Ping 
Published: July 2022

Abstract

Background: Cervical cancer is the fourth commonly occurred cancer in women around the world. However, it still lacks effective approaches to improve current prognosis of cervical cancer and prevent metastasis.

Objective: We aim to discover a promising biomarker for cervical cancer prognosis by utilizing bioinformatics analysis.

Methods: Gene expression was analyzed by the datasets from The Cancer Genome Atlas Program-Cervical squamous cell carcinoma and endocervical adenocarcinoma (TCGA-CESC) dataset and three independent patient cohort datasets. Biological process and pathway enrichment were performed by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways analysis. Immune infiltration was analyzed through TISIDB tool.

Results: SPP1 gene was highly expressed in cervical cancer tissues. In addition, SPP1 was positively correlated to advanced CESC stages and nodal metastasis status. SPP1 co-expressed genes are mainly enriched in immunological processes. Furthermore, SPP1 expression is involved in immune infiltration level, in which several tumour infiltrating lymphocytes are correlated with SPP1. SPP1 overexpression promotes a wide spectrum of chemokines and immunoinhibiors which contribute to CESC progression.

Conclusions: SPP1 is a promising biomarker and a prognostic factor of CESC. Tumour infiltrating lymphocytes are also possibly regulated by SPP1. Our study suggests that investigation on SPP1 is a new direction for CESC therapy.