bluuebunny/crossref_metadata_2025_split huggingface dataset:
On the comparative impact of self-assessment and peer assessment on Iranian male and female EFL learners’ accuracy in speech
Authors: Ferdosipour Atefeh 
Published: August 2022

The current study tried to explore the effects of assessment types and learners’ gender on EFL learners’ performance in speech accuracy. To this end, 60 homogenous students out of 90 students from Rahe Farda Institute in Bastak in Hormozgan province were selected based on the Quick Oxford Placement Test. The instruments of the study were an Oxford Placement Test, peer and self-assessment questionnaires adopted from Patri and Weir’s Analytic Speaking Criteria. The results were calculated using SPSS version 20. It can be seen that the means were close together, but the mean score for the male students was a little higher than that of the female students. According to the outcomes, assessment types had a significant influence on performance in speech accuracy and peer-assessment was more effective than self-assessment on performance in speech accuracy.

Keywords: Peer assessment, self-assessment, speech;
Risk factors and outcomes of emergency intervention in pregnant women with placenta previa: an observational study
Authors: KELEŞ Ayşe , AYDOĞMUŞ Süheyla , YUCEL CELİK Ozge , DAGDEVİREN Gulsah , OBUT Mehmet , ÇELEN Şevki , ÇAĞLAR Ali 
Published: August 2022

Aim: To investigate the risk factors and outcomes of emergency intervention in pregnant women with placenta previa (PP).
Material and method: This retrospective study was conducted between June 2015 and January 2021. Pregnant women with PP were divided into emergency and planned intervention groups according to surgical planning. The groups were compared in terms of demographic characteristics, presence of antepartum hemorrhage (APH), operation characteristics, and maternal and neonatal outcomes.
Results: A total of 434 patients with PP were analyzed. The frequency of PP was 0.52%. The emergency intervention was performed in 168 (38.7%) pregnant women, whereas planned intervention was performed in 266 (61.3%). APH was present in 208 (47.9%) patients; the presence of APH was associated with increased risk of emergency intervention by 3.026 [95% confidence interval (CI), 1.990–4.603; p = 0.000]-fold. The weight gained during pregnancy was associated with reduced risk of emergency intervention by 0.932 (95% CI, 0.887–0.978; p = 0.004)-fold. In the emergency intervention group, more additional surgical procedures and massive transfusion were performed during the operation (p = 0.000 and p = 0.000) Emergency intervention resulted in an increase in adverse maternal and fetal outcomes by 3.064 (95% CI, 1.571–5.975) and 7.5 (95% CI, 4.841–11.620)-fold, respectively.
Conclusion: The frequency of an emergency intervention is high in those with PP and is associated with increased adverse maternal and neonatal outcomes.The most effective factor in the prediction of emergency intervention is APH.
Can Serial Internal Optic Nerve Sheath Diameters Measured with Ultrasonography Predict the Prognosis of Medical Intensive Care Patients?
Authors: ÖZDEMİR Uğur , YILDIZ Şeyma , TANBUROĞLU Derya , TÜRKOĞLU Melda , AYGENCEL Gulbin 
Published: August 2022

Aim: Optic nerve sheath (ONS) contains subarachnoid space, pia mater layer, and optic nerve fiber layer. ONS diamater (ONSD) without subarachnoid space is known as internal ONSD (iONSD). There are too many astrocytes and vascular network in iONSD area. Astrocytes are known to swell with systemic infection, inflammation, pro-inflammatory cytokines, some metabolic disorders, and oxidative stress. Also, this vascular network can vary by many ICU pathologies. This study investigated the relationship between serial iONSD measured with USG and the prognosis of critically ill patients who had no intracranial pathologies.
Material and method: The mean iONSD values for the right eye (RiONSD) and left eye (LiONSD) were measured. MiONSD (the mean of RiONSD and LiONSD) and DiONSD (the difference of final and admission MiONSD of ICU stay) were calculated.
Results: 35 ICU patients without intracranial pathologies were included. There was a significant difference between survivors and non-survivors for DiONSD (-0.35 [(-0.85)-(-0.10)], 0.60 [(0.21)-(1.00)] mm respectively, p=0.0001). The multivariate analysis performed between DiONSD, SOFA, and APACHE II score (p=0.033, OR=10.66 %95 CI [1.21-93.92]) indicated that DiONSD was an independent risk factor for mortality. DiONSD values greater than + 0.25 mm was determined to be a predictor of mortality with 75% sensitivity and 95% specificity (LR=14.25, AUC=0.905, p=0.0001). There was a good corelation between DiONSD values and SOFA score, total fluid balance, sepsis, serum albumin level, and GCS level.
Conclusion: iONSD measurement with USG can be used to determine the prognosis of ICU patients who have no intracranial acute or chronic pathologies.
Prediction of Mine Water Inflow based on the Coupled Flow Characteristics of Multiple Water Conducting Structures
Authors: Zhao Jinhai , Liu Qi , Jiang Changbao , Wang Defeng 
Published: August 2022

Abstract
Because of various patterns of deep-water inrush and complicated mechanism, accurate prediction of mine water inflow is always a difficult problem for coal mine geologists. In this paper, the water inrush channel is divided into four basic water diversion structures: aquifer, rock fracture zone, fracture zone and goaf. The fluid flow characteristics in each water conducting structure were investigated by laboratory test and the multi-structure and multi-system coupling flow analysis model of different water conducting structures are established to describe the whole process of water inrush. Based on the research of water inrush flow path, the analysis model of different water inrush space structure was established and applied to the prediction of mine water inrush inflow. The results prove that, (1) the conduction sequence of different water-conducting structures and the changing rule of permeability caused by stress changes before and after the peak have important influences on the characteristics of mine water-gushing. Influenced by the difference of geological structure and combined with rock mass RQD and fault conductivity characteristics and other mine exploration data, the prediction of mine water inflow can be realized accurately. Take the water transmitting path in the multi-structure as the research object of water inrush, breaking through the limitation of traditional stratigraphic structure division, the prediction of water inflow and the estimation of potential flooded area was realized and water bursting intensity was predicted. It is of great significance to make a reasonable emergency plan.
Reduction of dental biofilm cariogenicity in patients with fixed orthodontic appliances by a combined Horizontal-Charters-modified Bass brushing technique and dietary advice: A randomized clinical trial
Authors: Saengphen Thanakorn , Koontongkaew Sittichai , Utispan Kusumawadee 
Published: August 2022

Abstract
Background: The orthodontic patients with inadequate oral hygiene have susceptibility to dental caries. Increased dental biofilm accumulation has been found in orthodontic patients. However, assessment of dental biofilm cariogenicity in these patients has not been reported. This open-label, two-arm parallel trial evaluated the effects of toothbrushing and dietary advice on dental biofilm maturity and dietary habit in patients with stainless steel (SSL) and elastomeric (EL) ligatures.Methods: At T0, diet habits, socio-demographic, medical problems, orthodontic treatment, and dental health behavior data were collected from 70 patients. The patients were randomized (1:1 ratio) to the SSL or EL group by simple randomization at T1. Dental biofilm cariogenicity was evaluated using a three-color-disclosing dye. The patients in both groups were instructed to brush their teeth using a combined Horizontal-Charters-modified Bass technique and dietary advice. The data were reassessed at the 4-week follow-up (T2). Results: At T1, new dental biofilm (median 50%; Q1, 32.66%; Q3, 71.13%) was highest followed by mature dental biofilm (median 26%; Q1, 20.42%; Q3, 47.93%), and cariogenic dental biofilm (median 8%; Q1, 4%; Q3, 22.92%) (p < 0.05), in SSL group. In the EL group, cariogenic dental biofilm (median 54.16%; Q1, 44.44%; Q3, 69.56%) was highly observed, while the median for mature and new dental biofilm was 25.0% (Q1, 18.18%; Q3, 36.18%) and 13.63% (Q1, 7.55%; Q3, 26.96%), respectively (p < 0.05). At T2, cariogenic dental biofilm in EL group demonstrated significantly greater reduction (47.04%) compared with the SSL group (8%) (p < 0.05). Cariogenic food consumption was low in two groups. However, dietary habits did not change in either group at T2.Conclusions: Combined toothbrushing effectively reduced cariogenic dental biofilm in orthodontic patients. Trial registration Thai clinical trials registry (TCTR20220221003)
Characterization of Synthesized Cellulose Derivatives in 1-Butyl-3-Methylimidazolium Chloride Ionic Liquid
Authors: BAKER MARIAM TEMITOPE 
Published: August 2022

Abstract
To obtain pure holocellulose, cellulosic wastes were chemically pretreated. Depending on the derivatizing agents used, the dissolution and functionalization of various holocelluloses obtained in 1-butyl-3-methylimidazolium chloride [BIMIM]Cl ionic liquid using different derivatizing agents such as cellulose acetate, cellulose phthalates, and cellulose ether. Cold acetone and dichloromethane were used to regenerate the dissolved product in ionic liquids, and the resulting ionic liquids were reused.The degree of substitution (DS) of the products obtained ranged from 1.00 to 2.77 at 100°C. FTIR analysis revealed important absorption bands which include: (C = O at ~ 1750 cm− 1, SP3 –CO at ~ 1250cm− 1, SP2 –CO at 1100cm− 1, for esters of cellulose acetate and phthalate, Aromatic –CH stretching at 1577cm− 1 for cellulose phthalate and –CO-CH2CH3 at 1720cm− 1 with the absence of SP2 bending frequency at 1250cm− 1 which confirms the successful synthesis of ethyl cellulose). XRD showed values at (2θ= ~14.5°, 17.0°, 22.7° and 34.5°) for all samples. Comparison of SEM images of the cellulose and derivatives showed little or no destruction of the fibre strands while EDS revealed C and O as (Elemental composition of all samples. Thermogravimetric analysis (TGA/DTA) showed the derivatives possessed higher thermal stability that the starting materials thus, producing materials with better application. All these revealed a successful extraction and purification of cellulose from wastes as well as the synthesis of cellulose derivatives.
Subthreshold Laser Treatment for Non-Center Involved Diabetic Macular Edema via Non-Damaging Retinal Laser Therapy (NRT)
Authors: Aydoğmuş Fatma Akkan , Kalaycı Defne , Gultekin Burcu Polat 
Published: August 2022

Abstract
Background/Objectives: To evaluate the efficacy of subthreshold laser treatment via NRT in patients with non-center involved diabetic macular edema (non-CI DME).Methods: In this prospective controlled study, NRT with 577 nm wavelength was performed to the edematous inner subfields as needed at 3 monthly intervals, while the control group received no treatment. If CI-DME developed in either group, intravitreal anti-VEGF was performed and the eye was excluded from subsequent analysis. Results: A total of 75 eyes (36 study eyes, 39 controls) were evaluated. The change in superior, nasal and temporal inner subfield thicknesses over time and between groups was found significant (P=0.004, P<0.001, P=0.04 respectively). Best corrected visual acuity (BCVA) change was not significant over time and between groups (P=0.69). Rates of CI-DME development requiring intravitreal anti-VEGF treatment were not different during the first and second years (P= 0.171, 0.908). No laser scar was detected in any eye in fundus autofluorescence imaging.Conclusion: NRT performed as needed at 3 monthly intervals is effective after 21 months of follow up in the treatment of non-CI DME and it was safe. With this method, it may be foreseen that BCVA will be better preserved in the long term by avoiding the possible side effects of conventional laser.
The responsibility of the EU in climate change mitigation: What is wrong with the recent EU targets?
Authors: Suárez-Eiroa Brais , Soto-Oñate David , Loureiro Maria 
Published: August 2022

Abstract
The European Union (EU) is a leading actor in climate international negotiations and a path-breaking example of sustainability. However, the EU’s current agenda on climate change has been built by disregarding essential features of this global process: accumulation of greenhouse gases over time, cascading regimen shifts within and across scales, and tipping points. We examine whether the EU’s recently declared climate targets are consistent with a reasonable allocation of responsibilities concerning global carbon budgets. This is relevant because the assumption of appropriate climate responsibilities is paramount for the collective coordination of polycentric actions towards the agreed common goal. We find that the current EU climate policy is inconsistent with the aspiration of preventing the +1.5 °C or +2 °C average global temperature increase in 2100, compared to preindustrial levels. We argue that the EU should aim for more responsible policies coherent with its responsible share of the global budget.
Thermal diffusion and diffusion thermo impacts with Cattaneo – Christov theories on the peristaltic motion of a non – Newtonian micropolar nanofluid inside a tapered stenosis artery
Authors: El-Dabe Nabil T. M. , Abouzeid Mohamed , Ouaf Mohmoud , Mostapha Doaa R. , Mohamed Yasmeen M. 
Published: August 2022

Abstract
The current investigation described the influences of Cattaneo – Christov heat flux, Soret and Dufour, Hall current. The vertical alternating current produces an electric field is applied on the peristaltic flow of non - Newtonian micropolar nanofluid. The fluid flows inside a tapered stenosed artery. The non – Newtonian fluid obeys the tangent hyperbolic model. The effects of heat generation absorption, joule heating, thermal radiation, chemical reaction, and the permeability of the porous medium are imposed. The slip velocity and thermal slip conditions are assumed. The convective conditions for nanoparticles concentration as well as concentration are constructed. The coupled differential systems of equations yield Soret and Dufour feature. The assumption of the long wavelength with low Reynolds number is employed to simplify the governing equations of fluid motion to be ordinary differential equations. Furthermore, the obtained analytical solutions of these equations are based mainly on applying regular perturbation method together with homotopy perturbation method (HPM). The impacts of the various physical parameters on the axial velocity, spin velocity, temperature, nanoparticles concentration and concentration are illustrated and drawn graphically via a set of graphs. It is noticed that the velocity dwindled with an enriching in the magnitudes of both Hartman number, and electromagnetic parameter. Whereas, the axial velocity elevates with an enlargement in Darcy number, tapering angle, and Hall parameter. Moreover, the spin velocity declines with the increment in the microrotation parameter. Also, it is found that the escalating in thermal relaxation time causes a decaying impact on the temperature. Furthermore, enhancement in the nano Biot number leads to a declination in the magnitude of nanoparticles concentration. The current analytical study is very significant in several medical implementations, like the gastric juice motion in the small intestine when an endoscope is inserted through it.
Penetration Study Of p-Methoxycinnamic Acid (PMCA) in Nanostructured Lipid Carrier, Solid Lipid Nanoparticles, and Simple Cream into the Rat Skin
Authors: Rosita Noorma , Sultani Angguni Addini , Hariyadi Dewi Melani 
Published: August 2022

Abstract
This study compared the ability of NLC, SLN, and cream systems in delivering Para Methoxycinnamic Acid (PMCA) to the dermis layer of the skin. Wistar rats were used as research subjects. NLC and SLN were made using the high shear homogenization method. Red nile was used as a penetration indicator based on its fluorescence. The interaction between fluorescence labeled NLC, SLN, or simple cream and rat skin was visualized by fluorescence microscopy. Observations were done after 2 and 4.5 hours of smearing the test sample. From observations, it was known that the system/lipid base could penetrate the stratum corneum delivering drugs. Penetration speed differs between systems as does the number of PMCAs that can be delivered. In this study, it can be concluded that the NLC system is able to deliver PMCA more quickly and in greater quantities to the dermis than SLN and Cream.
WITHDRAWN: Extension typologies and sustainable intensification:
Evidence from West Africa
Authors: Tabe-Oj Martin Paul Jr , Gebrekidan Bisrat , Lokossou Jourdain , Nyam Sebastian 
Published: August 2022

Abstract
Agricultural productivity and environmental sustainability are two important complementary sustainable development goals. However, potential trade-offs could exist in some production and farming systems. Sustainable intensification offers the promise of both increasing agricultural productivity and maintaining environmental sustainability, but its current use is puzzlingly low in many regions of the world, possibly due to information constraints. This paper examines the relationship between different typologies of extension systems and the use of sustainable intensification practices in three West African countries: Ghana, Mali, and Nigeria. Exploring the longitudinal nature of the dataset, we show that farmers with access to extension services are more likely to use sustainable intensification practices such as high-yielding and disease-resistant varieties, crop rotation, and intercropping with cereals, as well as the use of organic fertilizers. These relationships hold true for both farmers that are advised by both private and public extension agents. However, the biggest intensification gains are observed for farmers that are jointly advised by both private and public extension systems. Exploring what may be underlying the relationship between the different extension typologies and sustainable intensification, we find suggestive evidence that agricultural training may partly explain this positive relationship. Based on these insights, we conclude that farmer extension services and farmer advisory systems matter in bridging the trade-off between agricultural production and environmental sustainability.JEL codes: I38; J54; Q13; Q16
The estrogenic effect of Lysiphyllum strychnifolium (Craib) A. Schmitz water extracts in MCF-7 cells
Authors: Maenpuen Suwanna , Ekaratcharoenchai Niramai , Mongkolrob Rungrawee , Nualsanit Thararat , Kietinun Somboon , Krajarng Aungkana 
Published: August 2022

Abstract
Background
Lysiphyllum strychnifolium (Craib) A. Schmitz (LS) has been used to stimulate breast milk production in women after giving birth in the Northeast of Thailand. However, very little information is known about its estrogenic effect. The present study investigated the estrogenic effect of LS leaves water extracts compared with quercetin, one of the major compounds in LS, in MCF7 human breast cancer cells
Methods
The effect of LS leaves water extracts and quercetin on cell proliferation of estrogen receptor (ER)-positive breast cancer cells, MCF-7, was studied by MTT assay at a concentration range of 0 to 500 µg/ml. The expression of estrogen-dependent genes, the pS2, ERα, ERβ and Bcl-xL, were also examined by real time RT-PCR, and the expression of ERα protein was detected by Western blotting.
Results
The quercetin content in LS water extract was 285.67 ± 0.11 ug/g. The expression levels of the pS2 and Bcl-xL genes in MCF-7 cells were found to be upregulated by LS leaves water extract (20 µg/ml) and 17β-estradiol (E2) (10− 5 M) compared with the untreated control. The ERα gene expression was found to be upregulated by quercetin (0.16 µg/ml) and E2 (10− 5 M) compared with the untreated control. In addition, quercetin (0.16 µg/ml) and LS extract (0.8, 4, 20 µg/ml) decreased the phosphorylation of ERα at Ser167 (pERα (ser167)) and LS extract (20 µg/ml) decreased ERα, but there was no significant effect on the ERα at Ser118 (pERα (ser 118)) protein expression.
Conclusions
This study provided evidence for the potential estrogenic activities of LS leaves water extract. Since LS extract induced pS2 gene transcription, it was confirmed that the extract could affect the transcription of estrogen responsive genes causing estrogenic effects. The results also showed that quercetin, one of the LS compounds, upregulated ERα gene expression at 24-hour treatment.
High level of FANCI correlates with worse prognostic outcome and promotes tumor growth of lung adenocarcinoma partly by suppressing the activation of M1 macrophages
Authors: Li Wujin , Yu Mingdian , Zhang Jiguang , Huang Jianyuan , Lin Zhaoxian , Chen Jingbo , Jiang Guicheng , Lin Xing 
Published: August 2022

Abstract
FANCI, as a member of the Fanconi anemia (FA) complementation group, normally associates with FANCD2 to play an important role in ribosome biogenesis and DNA repair. However, the correlation of FANCI to prognostic value and the molecular mechanism in lung adenocarcinoma (LUAD) patients remain unclear. In the present paper, bioinformatics analysis was performed on LUAD data from TCGA and GEO database, and further to be confirmed by in vitro experiment. We found that high level of FANCI was significantly correlated with worse survival probability of LUAD patients. Moreover, the results from in vitro experiments revealed that high levels of FANCI were found in LUAD specimens and LUAD cell lines. Knockdown the expression of FANCI in A549 cells and H460 cells significantly inhibited the cell viability and clone formation of LUAD cells in vitro and in vivo. Furthermore, high FANCI level was negatively correlated with a variety of the tumor infiltrating immune cells. Importantly, overexpression of FANCI significantly inhibited the activation of M1 macrophages. All the data demonstrated that FANCI was a useful prognostic biomarker in LUAD patients and knockdown FANCI inhibited tumor growth of LUAD cells in vitro and in vivo partly by suppressing the activation of M1 macrophages.
Revisiting mandibular symphyseal shape in juvenile early hominins and modern humans using a deformation-based approach
Authors: Zimmer Veronika , Oettlé Anna , Hoffmann Jakobus , Thackeray John Francis , Zipfel Bernhard , Braga José 
Published: August 2022

Abstract
The juvenile mandible is important in the investigation of ontogenetic and evolutionary changes among early hominins. To more accurately describe complex shape variations, for the first time advanced methods from computational anatomy, and new fossil evidence are used to revisit the ontogeny of the mandibular symphysis in Australopithecus africanus and Paranthropus robustus. We assess which features of the mandibular symphysis best discriminate the growing symphysis in these fossil species, relative to the intraspecific variation observed among modern humans. When compared with more traditional approaches, our results are in line with previous studies and confirm that our approach eliminates potential methodological inconsistencies with the a priori definition of homologous landmarks and the tacit assumption that anatomical shapes are linear. By enabling detailed comparisons of complex shapes in juvenile mandibles, our proposed approach offers new perspectives for more detailed comparisons among Australopithecus, Paranthropus and early Homo in both southern and eastern Africa.