bluuebunny/crossref_metadata_2025_split huggingface dataset:
Volumetric breast density evaluation using fully automated Volpara software, its comparison with BIRADS density types and correlation with the risk of malignancy
Authors: Singh Neha , Joshi Pranjali , Singh Deepak Kumar , Narayan Shamarendra , Gupta Anurag 
Published: May 2022

AbstractBackgroundMammography is currently the modality of choice for mass screening of breast cancer, although its sensitivity is low in dense breasts. Besides, higher breast density has been identified as independent risk factor so it has been conceptualized that women with dense breasts should be encouraged for supplemental screening. In this study, we aimed to estimate the distribution of volumetric breast density using fully automated Volpara software and to analyze the level of agreement between volumetric density grades and Breast Imaging Reporting and Data System (BI-RADS) density grades. We also aim to estimate the distribution of breast cancer in different VDG and to find a correlation between VDG and risk of malignancy.ResultsVDG-c was most common followed by VDG-b and BIRADS grade B was commonest followed by grade C. The density distribution was found inversely related to the age. Level of agreement between VDG and BIRADS grades was moderate (κ = 0.5890). Statistically significant correlation was noted between VDG-c and d for risk of malignancy (p < 0.001).ConclusionDifficulties associated with the use of BI-RADS density categories may be avoided if assessed using a fully automated volumetric method. High VDG can be considered as independent risk factor for malignancy. Thus, awareness of a woman’s breast density might be useful in determining the frequency and imaging modality for screening.
Systematic Analysis of Publication Bias in Neurosurgery Meta-Analyses
Authors: Phua Qi Sheng , Lu Lucy , Harding Marguerite , Poonnoose Santosh Isaac , Jukes Alistair , To Minh-Son 
Published: May 2022

BACKGROUND:
Statistically significant positive results are more likely to be published than negative or insignificant outcomes. This phenomenon, also termed publication bias, can skew the interpretation of meta-analyses. The widespread presence of publication bias in the biomedical literature has led to the development of various statistical approaches, such as the visual inspection of funnel plots, Begg test, and Egger test, to assess and account for it.

OBJECTIVE:
To determine how well publication bias is assessed for in meta-analyses of the neurosurgical literature.

METHODS:
A systematic search for meta-analyses from the top neurosurgery journals was conducted. Data relevant to the presence, assessment, and adjustments for publication bias were extracted.

RESULTS:
The search yielded 190 articles. Most of the articles (n = 108, 56.8%) were assessed for publication bias, of which 40 (37.0%) found evidence for publication bias whereas 61 (56.5%) did not. In the former case, only 11 (27.5%) made corrections for the bias using the trim-and-fill method, whereas 29 (72.5%) made no correction. Thus, 111 meta-analyses (58.4%) either did not assess for publication bias or, if assessed to be present, did not adjust for it.

CONCLUSION:
Taken together, these results indicate that publication bias remains largely unaccounted for in neurosurgical meta-analyses.
Unprecedented early-summer heat stress and forecast of coral bleaching on the Great Barrier Reef, 2021-2022
Authors: Spady Blake L. , Skirving William J. , Liu Gang , De La Cour Jacqueline L. , McDonald Cathy J. , Manzello Derek P. 
Published: May 2022

The Great Barrier Reef (GBR) is predicted to undergo its sixth mass coral bleaching event during the Southern Hemisphere summer of 2021-2022. Coral bleaching-level heat stress over the GBR is forecast to start earlier than any previous year in the satellite record (1985-present). The National Oceanic and Atmospheric Administration (NOAA) Coral Reef Watch (CRW) near real-time satellite-based heat stress products were used to investigate early-summer sea surface temperature (SST) and heat stress conditions on the GBR during late 2021. As of 14 December 2021, values of instantaneous heat stress (Coral Bleaching HotSpots) and accumulated heat stress over a 12-week running window (Degree Heating Weeks) on the GBR were unprecedented in the satellite record. Further, 89% of GBR satellite reef pixels for this date in 2021 had a positive seven-day SST trend of greater than 0.2 degrees Celsius/week. Background temperatures (the minimum temperature over the previous 29 days) were alarmingly high, with 87% of GBR reef pixels on 14 December 2021 being greater than the maximum SST over that same 29-day period for any year from 1985-2020. The GBR is starting the 2021-2022 summer season with more accumulated heat than ever before, which could have disastrous consequences for the health, recovery, and future of this critical reef system.
Macroinvertebrate-based index of biotic integrity for assessing the ecological condition of Lake Wanchi, Ethiopia
Authors: Kuma Tolera , Tamire Girum , Beneberu Getachew 
Published: May 2022

Background: Lake Wanchi is one of the Ethiopian lakes that have huge ecological, socio-economic and aesthetic value. This study was conducted to assess the ecological condition of Lake Wanchi using the macroinvertebrate-based index of biotic integrity between September 2016 and should 2017. Methods: Four sampling sites (LWS 1, LWS 2, LWS 3, and LWS 4) were purposively selected. A rapid bioassessment protocol criterion was accustomed to categorize the sites. About 1249 macroinvertebrate individuals were collected using the D-frame net with a mesh size of 500µm. Physico-chemical analysis was also done to assess the link between the benthic macroinvertebrate structure and environmental factors within the system. Results: The benthic index of biotic integrity ranged from 12.54 to 100 and also the sites were categorized into three quality ranks: LWS 1 and 3 as fair, LWS 2 as good, and LWS 4 as very good. Conclusions: The study confirmed that Lake Wanchi was largely influenced by agricultural and other anthropogenic factors. This study concluded that the benthic index of biotic integrity is an appropriate tool for water quality and ecological assessment in the lakes.
Simulation model for the dynamics of dengue with asymptomatic transmission and the effect of temperature
Authors: Olarte García Julián Alejandro , Raigosa Osorio Steven , Manrique Arias Oscar Andrés , Abello Muñoz Carlos Alberto , Acosta Minoli Cesar Augusto 
Published: May 2022

Background: One of the fastest spreading vector-borne diseases in tropical and subtropical regions is dengue, which generates cost overruns for public health entities. Several factors can influence the dynamics of dengue virus transmission: environmental and climatic (abundance of vectors), interactions between hosts (infections by asymptomatic individuals), and population immunological factors. Given these conditions, it is necessary to carry out theoretical studies based on meteorological factors and asymptomatic transmission that are associated with both the existence of the vector and its incidence, in order to provide a scientific basis for health entities in decision-making. Methods: A mathematical model based on nonlinear ordinary differential equations is proposed to interpret the dynamics of dengue transmission in humans coupled to the dynamics of the Aedes aegypti species, considering the population of symptomatic and asymptomatic infected humans and the effect of temperature variability. The basic reproduction number was found and some simulation results based on the Runge-Kutta numerical method were obtained. Results: The simulations showed that the temperature had a directly proportional relationship with the basic reproduction number. The cases of infected people and carrier mosquitoes increased when the temperature peaks increased drastically; in low temperatures the infection persisted with low morbidity due to the survival of asymptomatic people. Conclusions: High temperatures tolerable by mosquitoes increase their life expectancy and their numbers in the environment which, together with a reservoir of asymptomatic infected people, leads to a higher incidence of the dengue virus in certain seasons or maintains its circulation in seasons of low temperatures, despite lower vector survival rates.
Internal control and supply of medicines in the pharmacy area of the Zarate Health Centre - 2021
Authors: Esteves Pairazaman Ambrocio Teodoro , Cueva Mestanza Ruben Eduardo , Leon Apac Gabriel , Chavez Flores Juana Elvira , Lizarme Arevalo Diana Justina , Caja Clemente Carolina Marisol , Ñañez del Pino Daniel 
Published: May 2022

Background: The purpose of this research was to evaluate whether internal control helps the supply of medicines in the pharmacy area of the Zarate health center in 2021. Methods: The research method was deductive and descriptive-observational. The approach was quantitative, as the analysis was observational based on documentary analysis. It was an applied, non-experimental, cross-sectional design. The population and sample were the documentation of internal control and medicine supply in the pharmacy area of the Zarate health center in 2021. Due to the nature of the research, a checklist was used as a data collection instrument, which was used to collect all the information from the documentation available at the study site. Results: As main results, it was found that the evaluation of internal control obtained a score of 63 out of 66 possible points, with 95.5% compliance, and the supply variable obtained a score of 37 out of 42 possible points, with 88.1% compliance. Conclusion: It was found that internal control affects and helps the supply of medicines in the pharmacy area of the Zarate health center in 2021.
Non-technical dimensions of communal wastewater treatment plant sustainability in peri-urban Yogyakarta, Indonesia
Authors: Brontowiyono Widodo , Boving Thomas , Asmara Adelia Anju , Rahmawati Suphia , Yulianto Andik , Wantoputri Noviani Ima , Lathifah Annisa Nur , Andriansyah Yuli 
Published: May 2022

Background: This study focuses on identifying non-technical aspects that influence the sustainability of communal wastewater treatment plants (WWTPs) in a peri-urban area of Indonesia. Methods: A questionnaire survey was conducted by random sampling using a method of descriptive analysis that combines qualitative and quantitative approaches. Economic support for communal WWTPs was measured by the community’s Willingness to Pay (WTP) and Ability to Pay (ATP). Results: The results indicate that social dimension, such as a community’s level of participation are critically important in sustaining communal WWTPs. In addition, institutional dimension influences the degree of satisfaction a community has toward the WWTP management. This support is reinforced by social capital in the form of a philosophy of mutual cooperation, like gotong royong (cooperation by members of a community to achieve a common goal) and swadaya (self-reliance). Conclusions: The findings of this study can be used in Indonesia to make policy recommendations for managing and ensuring sustainability of communal WWTPs on a non-technical dimension. Additionally, gotong royong deserves to be promoted internationally as a fundamental value for fostering participation and contribution.
Optimal Capacity Rationing Policy for a Container Leasing System with Multiple Kinds of Customers and Substitutable Containers
Authors: Yang Xufeng , Zhang Juliang , Jiao Wen , Yan Hong 
Published: May 2022

In this paper, we consider a container leasing firm that has elementary and premium containers, which are downward substitutable and for use by elementary contract customers (ECCs), premium contract customers (PCCs), as well as walk-in customers (WICs). ECCs can be satisfied by elementary containers or premium ones at discounted prices while PCCs only accept premium containers. WICs can be satisfied by any type of container at different prices. The objective is to maximise the expected total rental revenue by managing its limited capacity. We formulate this problem as a discrete-time Markov Decision Process and show the submodularity and concavity of the value function. Based on this, we show that the optimal policy can be characterised by a series of rationing thresholds, a series of substitution thresholds and a priority threshold, all of which depend on the system states. We further give conditions under which the optimal policy can be simplified. Numerical experiments are conducted to show the impact of the substitution of two items on the revenue, to compare the performance of the optimal policy with those of the commonly used policies and to investigate the influence of arrival rates on the optimal policy. Last, we extend the basic model to consider different rental durations, ECCs’ acceptance behaviour and endogenous prices for WICs. This paper was accepted by Jayashankar Swaminathan, operations management. Funding: This work was supported by National Natural Science Foundation of China/Research Grants Council of Hong Kong Joint Research Scheme [Grant 71661167009, N_PolyU531/16], National Natural Science Foundation of China [Grants 72171016, 71831001], and British Academy\Leverhulme Small Research [Grant SRG19\190059]. This work was also supported by Zhejiang Shuren University Research [Grant KXJ0121605] and Beijing Logistics Informatics Research Base. Supplemental Material: The e-companion and data files are available at https://doi.org/10.1287/mnsc.2022.4425 .
La revuelta catalana de 1640: Un estado de la cuestión.
Authors: GRACIA ARNAU Ivan 
Published: May 2022

Este articulo ofrece un balance historiográfico de la revuelta catalana de 1640, también conocida como Guerra dels Segadors. Se exponen, de forma sintética, las contribuciones que se han realizado al respecto desde la década de los sesenta del siglo XX hasta la actualidad, analizando los principales debates historiográficos a que se ha visto sometida la revuelta y exponiendo las nuevas perspectivas desde las que los historiadores se estan aproximando a la temática en la actualidad. El artículo sostiene que los estudios sobre este acontecimiento histórico han experimentado un viraje gradual desde la historia polítca hacia la historia cultural y han tendido a dejar a un lado el interés por las explicaciones de los hechos de largo recorrido cronológico para pasar a priorizar la comprensión de la experiencia de los individuos implicados en los mismos.
Palabras clave: revuelta catalana de 1640, Guerra dels Segadors, época moderna, historiografía.
Reflective astronomical telescopes with a large field of view and a wide wave band
Authors: Wang Xiaoheng , Zhu Jun 
Published: May 2022

Large-aperture ground-based astronomical telescopes are expected to have a large field of view (FoV) and a wide working wave band. We design two coaxial reflective telescopes based on a low-order even asphere and a high-order Q-con polynomial. Both telescopes have a primary mirror with a diameter of 6.5 m, a focal length of 24 m, and a working wavelength that stretches from ultraviolet to near-infrared (0.365–2.4 µm). The telescopes using an asphere and a Q-con polynomial have spectroscopic-survey fields of 3° and 3.4°, respectively. In these fields, the EE80D (diameter of 80%-enclosed light energy) values that can characterize the telescope image quality is less than

0

.

58

′
′

, and the spectral data can be obtained using fibers at the focal surface of the telescopes. Additionally, the two reflective telescopes can image celestial targets in a 0.4° FoV, and the root mean square diameters of the standard spot diagrams are less than 27 µm. By combining precise imaging measurements with the spectral data, the properties of celestial bodies can be better analyzed. The designed telescopes could enable the realization of astronomical spectroscopic surveys with both a large FoV and a wide waveband.
Self-powered photodetectors with a position-controlled array based on ZnO nanoclusters
Authors: Jing Yuanyuan , Xu Yingtian , Xu Chongyang , Li Li , Shi Linlin , Zhang He , Jin Liang , Zou Yonggang , Ma Xiaohui 
Published: May 2022

A self-powered ultraviolet (UV) photodetector (PD) with a position-controlled array based on zinc oxide (ZnO) nanoclusters (NCs) has been proposed. The structure of the special array makes it possible to reduce the light loss and improve the light trap. The PD innovatively modifies the structure of ZnO PDs, which is distinguished from other traditional devices. The results demonstrate that the ZnO NC array can spontaneously generate the carrier and successfully achieve the detection at zero bias under the radiation of UV light. In this study, the structure is fabricated with two different substrates of silicon (Si) and GaN. At zero bias voltage, the Si-based PD under 365 nm shows the responsivity and external quantum efficiency (EQE) reaching up to 14.1 mA/W and 4.79%, respectively, and the responsivity of the GaN-based detector can be obtained up to 59.9 mA/W; its parameter of EQE is 20.04%, the photocurrent is

1

0

−
5

A

, and the on/off ratio is 174. Our findings indicate that this structure of the device has potential for applications that require detection of light.
Photonic integrated circuits with bound states in the continuum: comment
Authors: Čtyroký Jiří , Petráček Jiří 
Published: May 2022

We point out that the electro-optic modulation of the bound state in
the continuum in a low-index dielectric-loaded slab

L
i
N
b
O

3

waveguide reported by Yu et al., [Optica 6,
1342 (2019)OPTIC82334-253610.1364/OPTICA.6.001342] is treated
incorrectly. According to our analysis based on both the perturbation
approach and numerical simulation, the electro-optic modulation is
more than an order of magnitude less efficient than the authors claim.
It thus remains unclear how the experimental results described in the
paper were obtained.
Colloidal quantum-dot light emitting diodes with bias-tunable color
Authors: Mu Ge , Rao Tianyu , Chen Menglu , Tan Yimei , Hao Qun , Tang Xin 
Published: May 2022

Although the performance of quantum-dot-based light emitting diodes (QLEDs) has been significantly enhanced over the past years, conventional full-color QLED displays still rely on the side-by-side pattern techniques of red (R)/green (G)/blue (B) quantum dots (QDs). Such lateral integration of multi-color pixels imposes technological difficulty in the development of high-resolution displays due to limited pixel density and fill factors. Herein, we demonstrate the development of full-color QLEDs with bias-tunable emission spectra by engineering mixed R/G/B QDs as light emitting layers. In Commission Internationale de l’Eclairage (CIE) chromaticity coordinates, QLEDs with bias-tunable color exhibit wide color variation ranging from red (0.649, 0.330) to green (0.283, 0.305) to blue (0.255, 0.264) upon increasing voltages and can be tuned to emit white light (0.316, 0.325). More importantly, the fabricated multi-color QLEDs show high luminance approaching

10

3

cd

m

−
2

and superior external quantum efficiency of 13.3%. Benefitting from the wide spectral tunability and light emitting efficiency, we believe the proposed multi-color QLEDs have great application prospects for both displays and lighting.
The added value of right ventricular function normalized for afterload to improve risk stratification of patients with pulmonary arterial hypertension
Authors: Vicenzi Marco , Caravita Sergio , Rota Irene , Casella Rosa , Deboeck Gael , Beretta Lorenzo , Lombi Andrea , Vachiery Jean-Luc 
Published: May 2022

Background
Risk stratification is central to the management of pulmonary arterial hypertension (PAH). For this purpose, multiparametric tools have been developed, including the ESC/ERS risk score and its simplified versions derived from large database analysis such as the COMPERA and the French Pulmonary Hypertension Network (FPHN) registries. However, the distinction between high and intermediate-risk profiles may be difficult as the latter lacks granularity. In addition, neither COMPERA or FPHN strategies included imaging-derived markers. We thus aimed at investigating whether surrogate echocardiographic markers of right ventricular (RV) to pulmonary artery (PA) coupling could improve risk stratification in patients at intermediate-risk.

Material and methods
A single-center retrospective analysis including 102 patients with a diagnosis of PAH was performed. COMPERA and FPHN strategies were applied to stratify clinical risk. The univariate linear regression was used to test the influence of the echo-derived parameters qualifying the right heart (right ventricle basal diameter, right atrial area, and pressure, tricuspid regurgitation velocity, tricuspid annular plane systolic excursion -TAPSE-). Among these, the TAPSE and tricuspid regurgitation velocity ratio (TAPSE/TRV) as well as the TAPSE and systolic pulmonary artery pressure ratio (TAPSE/sPAP) were considered as surrogate of RV-PA coupling.

Results
TAPSE/TRV and TAPSE/sPAP resulted the more powerful markers of prognosis. Once added to COMPERA, TAPSE/TRV or TAPSE/sPAP significantly dichotomized intermediate-risk group in intermediate-to-low-risk (TAPSE/TRV≥3.74 mm∙nm/s)-1 or TAPSE/sPAP≥0.24 mm/mmHg) and in intermediate-to-high-risk subgroups (TAPSE/TRV<3.74 mm∙(m/s)-1 or TAPSE/sPAP<0.24 mm/mmHg). In the same way, TAPSE/TRV or TAPSE/sPAP was able to select patients at lower risk among those with 2, 1, and 0 low-risk criteria of both invasive and non-invasive FPHN registries.

Conclusions
Our results suggest that adopting functional-hemodynamic echo-derived parameters may provide a more accurate risk stratification in patients with PAH. In particular, TAPSE/TRV or TAPSE/sPAP improved risk stratification in patients at intermediate-risk, that otherwise would have remained less characterized.