bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multi-dimensional study on the treatment of nonspecific neck pain with ultrasound-guided trigger point injection at the myofascial trigger point of upper trapezius muscles
Authors: Long Lu , Anwar Nadia , Li Shuangyu , Fan Meng , Zhou Li , Zang Qianwen , Li Yongyong , Wang Sanrong 
Published: February 2022

Abstract
Background: Nonspecific neck pain (NNP) is a common type of neck pain that causes serious health problems and is closely related to myofascial pain syndrome (MPS). Here, we compare the effectiveness of ultrasound-guided trigger point injection therapy (TPI) and conventional physical therapy treatment in patients with NNP in multiple dimensions. Methods: Thirty-eight patients with NNP were randomly assigned to the control group and ultrasound-guided TPI group, a single dose of 3 ml of 0.5% lidocaine was injected into each trigger points in all affected muscles under ultrasound guidance once a week for three weeks. The controls received conventional physical therapy treatment every other day for a total of three weeks. The visual analog scale (VAS) score, neck disability index (NDI), surface electromyography (sEMG), sonoelastography and infrared thermography characteristics were used to measured the effectiveness one week and four weeks after the whole treatment. Results: Compared with the control group, the TPI group showed improved pain and functional disability both at one-week and four-week assessment(P<0.01); and the TPI group showed improved electrical activity (P<0.05), elastic stiffness and skin temperature at the four-week assessment(P<0.01). Conclusions: Ultrasound-guided TPI on upper trapezius muscle can alleviate the pain, improves dysfunction for NNP than conventional physical therapy, and the multiple evaluation methods in treatment is more conducive to explore the underlying mechanism of NNP.Trial registration: The present study has been retrospectively registered on Chinese Clinical Trial Registry website (ChiCTR2100051009), Registered 10 September 2021.
Evaluation of Arginine and Tryptophan In Ovo Feeding on Production Performances, Glycogen Status, Intestinal Health and Immunity Related Gene Expression in Fast Growing Broilers
Authors: Nayak Nibedita , Rajini R. Asha , Sahu Amiya Ranjan , Kirubaharan J. John , Ezhilvalavan S. 
Published: February 2022

Abstract
The aim of this study was to evaluate the impact of in ovo feeding of essential amino acids (arginine and tryptophan) on post-hatch growth performances, organ indices, glycogen status, intestinal health, immune response and immunity related gene expression in fast-growing broilers. Total 700 fertile eggs (Cobb-400) divided into five groups and in ovo injection of arginine and/or tryptophan was administered on 18d of incubation through amnion to a depth of about 8 mm, sealed with paraffin wax and seted for hatching. Arginine feeding had significantly (P<0.01) improved hatch weight, chick/egg weight ratio and placement weight. Body weight gain was observed up to 21d of age in arginine fed group, while till 14d in combination group. Arginine had improved eviscerated and ready-to-cook weight significantly (P<0.01), but tryptophan increases breast yield per cent. Liver glycogen was significantly (P<0.01) higher in arginine fed groups. On 4d, villi height was significantly (P<0.05) increased in duodenum and ileum in all amino acid fed groups. On 35d, villi height was improved in duodenum and jejunum in tryptophan and combination groups. Higher HI-titre was observed on 4d in Arginine group; however, combination group had better HI-titre on 21 and 35d due to humoral immunity. IL-8 gene had high expression in tryptophan group, while IFN-γ expressed more in combination group. Hence, arginine and tryptophan in ovo feeding had improved production performances, glycogen status, intestinal health and immune response after proper metabolism over the feeding in day old chicks.
Analysis on 1481 case of medical complaints in a Tertiary Hospital in Fujian Province：a 5-year retrospective study
Authors: Jiang Jian , Huang fanqian , LI Huiting 
Published: February 2022

Abstract
Objective: This study aims to review the 1481 cases of medical complaints from Fujian Provincial Jinshan Hospital in the past 5 years for providing a reference for new hospitals to deal with medical complaints, optimize medical procedures, improve medical quality, and enhance patient experience.Method: The medical complaint information received by the hospital’s medical department and service center accepted and transferred by the health administrative department in the past 5 years was systematically reviewed and statistically analyzed according to the source of the complaint, the time of the complaint, the content of the complaint, the department of the complaint, the object of the complaint, and the resolution channel by using hierarchical clustering method.Results: The transfer of the health administration department (61.5%) and the acceptance of the service center (28.9%) were the main sources of medical complaints in hospital. The incidence of medical complaints per 10,000 patients in the hospital was between 3-6. The maximum number of complaints was 2017 (5.28 cases/10,000 population), and the least was in 2019 (3.2 cases/10,000 population). The median of complaints was 25, and May- Sep was the period of high incidence of medical complaints each year. In 5 years, the month with the largest number of complaints was May 2020 (41 cases), followed by August 2017(40 cases), and the month with the least number was November 2020 (11 cases). In the past 5 years, the hospital’s medical complaints were mainly in four aspects: medical process (n=329,22.2%), medical environment (n=282,19%), medical humanities (n=277,18.7%), and administrative management (n=209,14.1%). The most frequent complaints were in clinical departments, among which the emergency, outpatient, and pediatric departments accounted for more than 50%. The top three complaints were doctors (n=778,53%), logistics (n=284,19%), and nurses (n=239,16%). The main way to resolve complaints was letter and telephone feedback (n=1372,92.6%).Conclusion: Our research recommends that new hospitals change their concepts, pay more attention to the services and quality of medical resources and logistical support, follow the best practices of patient-centered, perfect various medical complaint channels, and establish multiple methods. They should also properly accept and dispose medical complaints, improve the timeliness and feedback efficiency of responding to medical complaints, strengthen communication, exchange, and dialogue, and improve patients’ medical experience and sense of gain.
Zoledronic Acid for prevention of bone and muscle loss after BAriatric Surgery (ZABAS) – A study protocol for a randomized controlled trial
Authors: Gam Søren , Gram Bibi , Juhl Claus Bogh , Hermann Anne Pernille , Hansen Stinus Gadegaard 
Published: February 2022

Abstract
BackgroundBariatric surgery has adverse effects in the muscular-skeletal system with loss of bone mass and muscle mass and an increase in the risk of fracture. Zoledronic acid is widely used in osteoporosis and prevents bone loss and fracture. Bisphosphonates may also have positive effects in skeletal muscle. The aim of this study is to investigate the effects of zoledronic acid for the prevention of bone and muscle loss after bariatric surgery.Methods/designThis is a randomized double-blind placebo-controlled study. Sixty women and men with obesity aged 35 years or older will complete baseline assessments before randomization to either zoledronic acid (5 mg in 100 ml isotonic saline) or placebo (100 ml isotonic saline only) three weeks before surgery with Roux-en-Y-gastric bypass (RYGB) or sleeve gastrectomy (SG). Follow-up assessments are performed 12 and 24 months after surgery. The primary outcome is changes in lumbar spine volumetric bone mineral density (vBMD) assessed by quantitative computed tomography (QCT). Secondary bone outcomes are changes in proximal femur vBMD assessed by QCT. Changes in cortical and trabecular bone microarchitecture and estimated bone strength will be assessed by high-resolution peripheral quantitative computed tomography (HR-pQCT). Cortical material bone strength at the mid-tibia diaphysis will be assessed using microindentation and fasting blood samples will be obtained to assess biochemical markers of bone turnover and calcium metabolism. Secondary muscle outcomes include whole body lean mass assessed using dual-energy X-ray absorptiometry. Dynamometers will be used to assess handgrip, shoulder, ankle, and knee muscle strength. Short Physical Performance Battery, 7.6-meter walking tests, 2-minute walking test and a stair climb test will be assessed as biomarkers of physical function. Self-reported physical activity level is assessed using International Physical Activity Questionnaire (IPAQ).DiscussionResults from this study will be instrumental for the evidence-based care of patients undergoing bariatric surgery.Trial registrationClinicalTrials.gov, ID: NCT04742010. Registered February 5th 2021.
What is the Influence of Maternal Weight Gain in Different Gestational Clinical Conditions on the Prole Weight in Pre-School Age?
Authors: Mariot Márcia Dornelles Machado , Kretzer Daniela Cortés , Becker Patrícia Cemin , Nunes Isadora Musse , Goldani Marcelo Zubaran , Bernardi Juliana Rombaldi , Silva Clécio Homrich da 
Published: February 2022

Abstract
BACKGROUND

The aim of the current study was to assess the influence of maternal weight gain in different clinical gestational conditions on the child's weight at pre-school age.
METHODS

longitudinal observational study of a prospective and controlled multiple cohort of 372 mother-child pairs from 2011 to 2016 in three hospitals in Porto Alegre (Brazil). Socio-demographic, prenatal and perinatal data were analyzed. Gestational weight gain (GWG) was categorized as "insufficient", "adequate" and "excessive". The Generalized Estimation Equations (GEE) model was used to assess changes in the Z score of the child's body mass index from birth to preschool age according to the GWG and gestational group.
RESULTS

A triple interaction effect was observed involving the gestational group, weight gain and time (p = 0.020) through an adjusted model. Maternal weight gain above the recommended is associated with a significant increase in the child's Z-BMI score over time, except for children from pregnant smokers. Children from diabetic (DM), hypertensive mothers, and the control group who had a weight gain above that recommended during pregnancy changed their nutritional status from eutrophic to overweight, becoming obese in the DM and hypertension groups and overweight in control.
CONCLUSIONS

Monitoring of the GWG, especially in the presence of hypertensive diseases and DM, should be effective to prevent children from developing overweight or obesity in preschool age with an important impact on health conditions in the future.
Determining HIV Risk for Adolescent Girls and Young Women (AGYW) in Relationships with “Blessers” and Age Disparate Partners: A Cross-Sectional Survey in Four Districts in South Africa
Authors: George Gavin , Beckett Sean , Reddy Tarylee , Govender Kaymarlin , Cawood Cherie , Khanyile David , Kharsany Ayesha BM 
Published: February 2022

Abstract
BackgroundHIV incidence among adolescent girls and young women (AGYW) remains high, with their male partners a prominent factor in sustaining these elevated rates. Partnership characteristics remain important metrics for determining HIV risk, with evidence indicating that AGYW engaged in transactional and age-disparate relationships facing greater HIV exposure. This study examines the risk posed to AGYW in a relationship with a “Blesser” only, defined as male who provides his female partner with their material needs or desires in exchange for a sexual relationship and age-disparate (5 or more years older).MethodsA cross -sectional household based representative sample of AGYW (aged between 12–24 years) were enrolled in the study (n=18 926) from the districts of City of Johannesburg and Ekurhuleni in the Gauteng province and the Districts of eThekwini and uMgungundlovu in the province of KwaZulu-Natal (KZN) in South Africa between March 13, 2017 to June 22, 2018. Participants completed a structured questionnaire and provided finger-prick blood samples for laboratory measurements. Our analysis used descriptive statistics and multiple binary logistic regressions accounting for survey weights, clustering and stratification. FindingsWhilst all relationships exposed AGYW to potential HIV risk, multiple binary logistic regression analysis revealed that AGYW in a relationship with a Blesser and an age disparate partner were more likely to be HIV positive (AOR: 3.12, 95% CI: 1.76-5.53, p <0.001), diagnosed with an STI (AOR: 4.60, 95% CI: 2.99-7.08, p <0.001), had 2 or more sexual partners in the previous 12 (AOR: 6.37, 95% CI: 3.85-10.54, p <0.001), engaged in sexual activity at age 15 or younger (AOR: 3.67, 95% CI: 2.36-5.69, p <0.001) and more likely to have ever been pregnant (AOR: 2.60, 95% CI: 1.24-5.45, p <0.05) than those not in a relationship with a Blesser and age-disparate partner. ConclusionDifferent relationships present different HIV to AGYW. AGYW who had engaged in relationships with both a Blesser and an age-disparate partner were at greater HIV risk when examined against these relationships independent of one another. The data reveals the compounded HIV risk of being in both a transactional and age-disparate relationship.
Tree Removal Changed The Drumming Behaviour of A Japanese Pygmy Woodpecker
Authors: Onoda Setsuko 
Published: February 2022

Abstract
The Japanese pygmy woodpecker (Dendrocopos kizuki), called “kogera” in Japanese, normally drums on trees. However, during observations conducted over seven years in the Satoyama landscape of Japan, the author discovered the unique behaviour of a Japanese pygmy woodpecker individual. The woodpecker often preferred to drum on metal plates of telephone poles to seek the metal’s specific high-pitched sound. This case study suggests that landscape diversity can translate into behavioural diversity within species.
Effect of paracentesis on the survival of patients with terminal cancer and ascites: A propensity score-weighted analysis of the East-Asian collaborative cross-cultural Study to Elucidate the Dying process
Authors: Masuda Ken , Ishiki Hiroto , Yokomichi Naosuke , Yamaguchi Takuhiro , Ito Tetsuya , Takatsu Hana , Amano Koji , Hiramoto Shuji , Yamauchi Toshihiro , Kawaguchi Takashi , Mori Masanori , Matsuda Yosuke , Yamaguchi Takashi 
Published: February 2022

Abstract
Purpose: Paracentesis is among the most widely utilised treatments for Malignant ascites (MA). However, paracentesis in patients with MA has the potential to be associated with life-shortening effects. Thus, this study aimed to investigate whether paracentesis affected the duration of survival in such patients.Methods: We performed a post-hoc analysis of a prospective multicenter observational study investigating the dying process and end-of-life care in patients with terminal cancer, admitted to 23 palliative care units in Japan. Survival duration was compared between patients who did (paracentesis group) and did not undergo paracentesis (non-paracentesis group). We used inverse probability of treatment weighting (IPTW) to control for baseline covariates between groups.Results: Among the 1,896 initially enrolled patients, 568 with ascites were included in the study cohort. Eighty-five (15.0%) patients underwent paracentesis. The primary tumor site was the pancreas (51.9%, n=295), followed by the gastrointestinal tract (22.7%, n=129). Non-adjusted median durations of survival were 22 days (95% confidence interval [CI]: 16–25) and 12 days (95% CI: 11–13) in the paracentesis and non-paracentesis groups, respectively (hazard ratio [HR]: 0.69, 95% CI: 0.54–0.88; p=0.003). The IPTW-adjusted median survival durations were 22 (95% CI: 16–25) and 16 days (95% CI: 12–22) in the paracentesis and non-paracentesis groups, respectively (HR: 0.89, 95% CI: 0.64–1.24; p=0.492). No serious adverse events occurred in the paracentesis group.Conclusions: Paracentesis does not negatively affect the survival of patients with cancer and MA and can be a standard treatment in palliative care settings.
Developing a core risk factors set for assessment of breast cancer risk in Iranian females: A qualitative Delphi consensus.
Authors: Manouchehri Elham , Roudsari Robab Latifnejad , Najafi Tahereh Fathi , Ebadi Abbas , Shandiz Fatemeh Homaei , Taghipour Ali 
Published: February 2022

Abstract
Background: There have been several methods designed to assess the risk of breast cancer. But according to studies conducted in Iran, the risk to Iranian women could not be accurately calculated with current tools. The aim of this study was to obtain consensus regarding potential breast cancer risk factors in Iran. Methods: A long list of risk factors identified from an integrative review of literature and specialist interviews (round 1) were used to design a questionnaire survey. In round 2 specialists were asked to rate the importance of each risk factor. Items considered very important after round 2 were carried out to the primary draft of core risk factors set and less important items were excluded. In round 3, respondents were asked to reprioritize moderate important risk factors. The items considered very important in round 3 must be included in core risk factors set.Results: In first round 11 specialists were interviewed and a total of 119 items were obtained of the first round and results of integrative review of literature. 30 specialists (response rate 50%) prioritized risk factors of BC in round 2. 51 were carried forward to the round 3 for consensus. No consensus was reached on any of the risk factors that went into Round 3 (response rate 86.7%). Therefore, a list of risk factors containing 25 important risk factors for breast cancer were obtained.Conclusion: This study highlights the items experts feel would be most important to include in the clinical assessment of breast cancer risk in Iran. With the results of this study, it is possible to provide appropriate and usable tool for screening high risk women in primary health care in Iran.
The Asbestos Contamination of Body Powder And Its Effect On Ovarian Health
Authors: Yin YS , Liu HY 
Published: February 2022

Abstract
Objective Investigation of asbestos pollution in body powder, and to explore the influence of asbestos contamination of body powder on ovary. Methods X-ray diffraction combined with polarized light microscopy was used to detect asbestos in body powder sold offline and online in China. Forty-two female SD rats were distributed into the control group, the talc group, the asbestos group, and the asbestos+talc group 0.2 ml corresponding powder suspension of 125mg/ml concentration was injected through the reproductive tract once a day for 180 days. At 90 and 180 days, CA125 and HE4 were measured, and the ovaries of rats were taken for pathological sections. Results A total of 13 asbestos samples were detected in 193 samples. The asbestos detection rate of online samples was higher than that of offline samples. The asbestos detection rate of samples in prices less than 10 Chinese Yuan was the highest. At 90 days and 180 days, the levels of CA125 and HE4 in each experimental group were increased, and the HE4 in the asbestos+talc group was higher than that in the asbestos group and talc group.At 180 days, the CA125 and HE4 levels of experimental groups were higher than those at 90 days. At 180 days, in the cortical area of rats in the asbestos+talc group, granular cell dysplasia was found in the follicles, and pathological mitotic figures were observed. Conclusion Powder mixture of talc and asbestos in low concentration entering the body through the reproductive tract in long time can damage ovarian health.
Clinicopathological Characteristics and Prognostic Factors in Axial Chondroblastomas: A Retrospective Analysis of 61 Cases and Comparison with Extra-Axial Chondroblastomas
Authors: Zheng Bo-Wen , Zheng Bo-Yv , Niu Hua-Qing , Wang Xiao-Bin , Lv Guo-Hua , Li Jing , Zou Ming-Xiang , Ouyang Zhi-Hua 
Published: February 2022

Abstract
Background: The clinical characteristics and prognostic factors of axial chondroblastoma (ACB) are still poorly understood.Purpose: To characterize clinicopathological characteristics in a large ACB cohort and investigate their correlation with survival. We also sought to compare these results with extra-axial CB (EACB).Methods: Our institution's local database was retrospectively reviewed and included a total of 132 CB patients, including 61 ACB patients and 71 EACB patients. Immunohistochemistry was used to assess the expression levels of Vimentin (Vim), S100, and cytokeratin (CK) on tumor cells in 132 tissue specimens.Results: Overall, ACB and EACB had similar characteristics, except for older age and tumor size, as well as higher Vim expression, incidence of surrounding tissue invasion and postoperative sensory or motor dysfunction. Whereas wide resection and absence of invasion of surrounding tissues were consistently associated with favorable survival in the ACB and EACB cohorts in univariate analysis, most parameters showed differential prognostic significance between the 2 groups. Significant prognostic factors for local recurrence-free survival in multivariate analysis included the type of resection and chicken-wire calcification in the ACB cohort. Multivariate analysis of overall survival demonstrated that the type of resection was a significant predictor in the ACB cohort, whereas the type of resection and postoperative sensory or motor dysfunction were predictive of overall survival in the EACB group.Conclusion: These data suggest that there may be distinct biological behaviors between ACB and EACB and may provide useful information to better understand the prognostic characteristics of patients with ACB and to improve outcome prediction in patients with ACB.
Source Apportionment and Lung Cancer Risk Assessment of PM2.5-Bound Polycyclic Aromatic Hydrocarbons in an Industrial City in Northwestern China
Authors: He Feifei , Lu Jianjiang , Liu Zilong , Niu Junfeng , Li Zhuoying 
Published: February 2022

Abstract
In this study, we investigated the occurrence of particulate matter (PM2.5)-bound polycyclic aromatic hydrocarbons (PAHs) in the atmosphere in Shihezi, China and estimated their incremental lifetime cancer risk (ILCR). In addition, the potential sources of PM2.5-bound PAHs were statistically estimated using principal component analysis and positive matrix factorization. The backward trajectory was employed to determine the potential source area using the HYSPLIT software. Concentrations of PM2.5 and 16 PM2.5-bound PAHs ranged from 4.32 μg/m3 to 114.67 μg/m3 and 6.26 ng/m3 to 114.79 ng/m3, respectively, with the highest PAH concentrations occurring in the winter. Three principal components were analyzed by PCA, namely a combination of coal combustion sources and vehicle emissions, fugitive dust, and industrial emissions. Five sources were analyzed by positive matrix factorization (PMF) including coal combustion, vehicle emissions, fugitive dust, industrial emissions, and natural gas emissions. Risk assessment analysis showed that source-specific lung cancer risk assessment was in the 10-6–10-5 range, which constitutes a cancer risk that exceeds the guideline safety value (10-6) according to the U.S. Environmental Protection Agency. It is necessary to take measures to reduce the concentration of PM2.5-bound PAHs in order to reduce human health hazards.