bluuebunny/crossref_metadata_2025_split huggingface dataset:
Resectable Gastric Adenocarcinoma Cancer and the Role of Early Feeding on Clinical Outcome
Authors: Ida Bagus Budhi 
Published: March 2022

Background: Gastric adenocarsinoma is one of the most common gastrointestinal tract cancer, it could be found either in elderly or young patients. Surgical resection is still the main therapeutic option and the gold standard for the resectable cases. Enhanced recovery protocols has been announced to improved the clinical outcome in of gastrointestinal cancer surgery. Especially in upper GI cancer, which still challenging in starting the oral feeding after surgical resection. We will reported the clincal outcome of early feeding on resectable gastric adenocarsinoma patients.

Methods: This was a retrospective study, taken from January 2018 - December 2020. All resectable gastric adenocarsinoma patients were included. Tumor locations, type of resection and reconstruction were evaluated. All patients had early oral feeding from the first post operative day, continued with liquid and semi solid food. The short term outcome were recorded including the anastomose leakage and surgical site infection.

Results: We reported eight gastric cancer patients during this study, 1 patient was young gastric cancer patiens and the rest were > 50 years old patients. Gastric anthrum was the most common tumor site with partial gatrectomy and Billroth II have been done. 3 patients were corpus site and 1 case of fundus cancer, total gastrectomy and roux en y esófago-jejunostomy reconstruction was done.

We found no anastomosis leakage. No SSI and no readmission associated with post operative morbidity.

Conclusion: Early feeding on resectable gastric adenocarsinoma patients was feasibel, has good clinical outcomes and could tolerated well, no matter what type of gastric resection we did.
A Single Amino Acid Residue Defines the Difference in NLRP3 Inflammasome Activation between NEK7 and NEK6
Authors: Jeltema Devon , Wang Jihong , Cai Juan , Kelley Nathan , Yang Zhe , He Yuan 
Published: March 2022

Abstract
The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is a critical component of the innate immune system that is activated by microbial infections and cellular stress signals. The molecular mechanism of NLRP3 inflammasome activation remains not fully understood. As an NLRP3-interacting partner, NEK7 has emerged as a critical mediator for NLRP3 inflammasome activation. In contrast to NEK7, NEK6, the closely related member of the NEK family, does not support NLRP3 inflammasome activation. In this study, we show that the mouse NEK7 catalytic domain, which shares high sequence identity with the counterpart of NEK6, mediates its interaction with NLRP3 and inflammasome activation in mouse macrophages. Within their catalytic domains, a single amino acid residue at a corresponding position (R121NEK7, Q132NEK6) differentiates their function in NLRP3 inflammasome activation. Surprisingly, substitution of the glutamine residue to an arginine residue at position 132 confers NEK6 the ability of NLRP3 binding and inflammasome activation in mouse macrophages. Furthermore, our results suggest a structural pocket surrounding the residue R121 of NEK7 that is essential for NLRP3 binding and inflammasome activation.
Türkiye’de Hanehalkı Nakit Kullanımını Belirleyen Faktörler
Authors: ÇEVİK Saygın , DOĞRUKÖK Mehmet 
Published: March 2022

Bu çalışmada alışverişlerdeki ödemelerde nakit kullanımında etkili olan faktörler TCMB tarafından 2020 yılında gerçekleştirilen Nakit Kullanım Alışkanlıkları Anketi verileri
kullanılarak araştırılmıştır. Probit model; demografik faktörlerin, işleme ilişkin özelliklerin ve nakde ilişkin tutum ve yargıların kişilerin nakit ile ödeme yapma tercihinde belirleyici olduğunu göstermektedir. Çalışmanın ana bulgusu; demografi ve işlem özelliklerine ek olarak, nakdi diğer ödeme yöntemlerinden ayıran özelliklerden kaynaklanan tutum
ve yargıların nakit kullanma tercihinde açıklayıcı oluşudur. Sonuçlar, nakit kullandığında bütçe kontrolü sağlanacağını ve nakdin diğer ödeme yöntemlerine göre daha güvenli olduğunu düşünenlerin nakit kullanma olasılığının daha yüksek olduğunu göstermektedir.
Kurumsal Sosyal Sorumluluk ve Firma Riski: Borsa İstanbul’da Bir Uygulama
Authors: BORAK Metin , DOĞUKANLI Hatice 
Published: March 2022

Kurumsal sosyal sorumluluk (KSS) faaliyetlerinin firma riskini azaltması beklenmektedir. Çünkü KSS faaliyetlerinin özsermaye ve borç maliyetini, bilgi asimetrisini azaltırken
finansal performans ve firma itibarını artırdığı bilinmektedir. Bu çalışma, KSS’nin firma riski (toplam risk, sistematik risk ve sistematik olmayan risk) üzerindeki etkisini incelemektedir. Çalışmanın örneklemi, 2009-2020 yıllar arasında Borsa İstanbul’da faaliyet gösteren ve kurumsal yönetim derecelendirmesi yaptıran firmaları kapsamaktadır. Sonuç
olarak çalışmanın örneklemi 37 firma ve 339 gözlemden oluşmaktadır. Elde edilen bulgular, KSS’nin toplam, sistematik ve sistematik olmayan risk üzerinde istatistiksel olarak
anlamlı bir etkisi olmadığını göstermektedir. Elde edilen bu sonuçlar, açıklayıcı değişkenlerin bir yıl gecikmeli değerlerinin kullanılması durumunda da değişmemektedir.
The Importance of Vednaadhyaya in Clinical Diagnosis of Childhood Diseases
Authors: Dattatrya G. Parde  , Sadhana D. Avhale  
Published: March 2022

The knowledge of Ayurveda have been divided in eight branches i.e., Ashtangayurveda. Out of which Kaumarbhritya is the branch of Ayurveda, which deals with the knowledge of diseases and care of child right from conception till adolescence. Kashyap Samhita is the most important and main classical text of the Kaumarbhritya. The Kashyap Samhita is divided in various sections (Sthana) of which Vedanadhyaya is 25th Chapter of Sutrasthana where the symptomology of various diseases in children’s are explained and it helps in pediatric examination and diagnosis as children are not capable to speak about their symptoms themselves. The present review article is the humble effort to investigate the classical text of the Vedanadhyaya and its modern aspects. It is observable that Acharya Kashyap has integrated a broad collection of diseases of different system like skin, ENT, gastro-biliary, hematology and urinary system and has also included the Balgrahas. The symptoms described are truthful and rational in modern logical era also. Therefore, a comprehensive study of Vedanadhyaya is necessary for appropriate understanding of Ayurvedic point of view for pediatric diseases and their ordinary discriminative symptoms. It reinforces the view, that children are not miniature adults and diseases in pediatric age group have different features and requires understanding of it. This review article highlights the importance of Vednaadhyaya in clinical diagnosis of childhood diseases.
Computational Study of Charge Density Produced in N2:H2 Plasma Actuator
Authors: Khalaf Thamir Hameed , Ghayb Dawser Hussain 
Published: March 2022

Numerical simulation of charge density produced in plasma actuators is dependent upon the development of models dealing with electrical properties. The main aim of this work is to investigate the characteristics surface charge density and space charge density of DBD plasma actuator. A simple design of surface dielectric barrier discharge plasma actuator is used in the study. The discharge gas was N2:H2 mixture with applied voltage equal to 1.5 kV. A theoretical plasma model is used to establish the charge density details. Results show that surface charge density increased in value and spread in width alone the exposed electrode as the voltage increased and reached to the amplitude value.
HIGHLIGHTS

In plasma diagnostics studies, charge density is one of the important parameter
The paper includes simulation to charge density in plasma actuator with two gases which are N2 and H2
The results very useful to follow up the electric field and flow of gases

GRAPHICAL ABSTRACT
Trend in hydrological series and land use changes in a tropical basin at Northeast Brazil
Authors: Da Silva Lorena Souza , Ferraz Lorena Lima , De Sousa Lucas Farias , Silva Santos Carlos Amilton , Rocha Felizardo Adenilson 
Published: March 2022

Flow is one of the hydrological variables of greatest interest due to its connection with water availability and its multiple uses. However, in recent years this resource has been threatened by intense land use and climate change, affecting patterns previously considered to be stationary. The goal of this study was to evaluate trends in changes of patterns of flow, precipitation, and land use in a basin located in the Brazilian Cerrado. 33 years of rainfall, fluviometric, and land use data were used, covering the period of 1985 to 2018 on an annual scale. Mann-Kendall and Sen Slope’s nonparametric test was applied to evaluate the trends in temporal series, as well as the Spearman Rho and Pettit, which were used to analyze the correlations between variables and detect the point of change in the series, respectively. The results show statistically significant trends in flow reduction over time. At the same time, a considerable reduction in natural areas occurred, with an increase of +750% in agricultural areas. The results also show that although a tendency to reduce precipitation was detected, its magnitude was not significant, with land use changes being the main factor for the negative changes in the flow of the Rio Grande tributary.
La innovación social, una apuesta desde la extensión universitaria por el desarrollo regional
Authors: Valenzuela Tovar Sylvia María 
Published: March 2022

Conscientes de la importancia e impacto de la innovación social en el contexto colombiano y latinoamericano como estrategia de transformación y desarrollo, así como con el fin de contribuir al fortalecimiento de la extensión universitaria en Latinoamérica y el Caribe, miembros de la Red Nacional de Extensión Universitaria y la Unión Latinoamericana de Extensión Universitaria (ULEU) han venido trabajando en los últimos años en el impacto de una de las modalidades de la llamada “tercera función”.
El presente documento contiene entonces una síntesis de lo analizado durante un par de años, partiendo de una breve introducción a la innovación social, seguida de una reseña del panorama en Colombia, Latinoamérica y el Caribe, para continuar con la presentación de algunas prácticas exitosas en la materia y finalizar a modo de reflexión para los lectores, con una serie de retos y desafíos en la materia, en especial para el caso colombiano.
Role of Stevia in Diabetes
Authors: Koser Nazia , Jaffer Hafiza Madiha 
Published: March 2022

Around 80% of the world populaces rely only upon plants for their wellbeing and recovery. While in the developed countries, dependence on medical procedure and drug medication is more habitual nevertheless in the recent times, an ever increasing number of individuals are preferring natural supplements. These days inspiration of individuals towards herbs is expanding because of the worry about the adverse effects of synthetic medications. Stevia is a nutritious sugar and could be of tremendous assistance for diabetic patients. It has an extremely low caloric value. Stevia contains two glycosides, in particular stevioside and rebaudioside A. Besides glycosides, Stevia contains an assorted combination of labdanediterpenes, triterpenes, stigmasterol, tannins as well as volatile oils. One might say that Stevia is a very secure and a non-harmful sugar for diabetics and might be useful in preventing cardiovascular ailments in patients with long-standing diabetes in its long term use. The feasible glucose lowering activity is because of the immediate effect of steviosides on pancreatic beta cells to discharge more insulin and to work on their capacity in gluco-toxicity. It can likewise force its hypoglycemic impact as it improves the first stage insulin reaction and consequently decreases the glucagon levels. It is in this way firmly suggested for the use of diabetic patients and might be utilized as a sugar substitute also with an extraordinary level of viability and wellbeing. Because of the attention on stevia for individuals with diabetes, many individuals keep thinking about whether it can treat or fix the condition. Presently there is no cure for diabetes, yet individuals can deal with the condition by using medications and by changing way of life. Stevia can assist with supporting these way of life changes. Consuming stevia instead of sugar in sweetened beverages and foods might assist individuals with diabetes settle their blood glucose levels. This substitution for sugar may likewise decrease the quantity of calories that an individual consumes, which is probably going to help in weight reduction. As excessive fat increases the risk of type 2 diabetes and its complications, which consists of heart and kidney issues.
Analisis Konsep Mahar Berupa Hafalan Ayat Al-Qur’an Dalam Perspektif Madzahibul Arba’ah
Authors: Hafid  
Published: March 2022

Artikel ini membahas tentang ayat-ayat Al-Qur’an tentang konsep mahar pernikahan berupa hafalan ayat al-Qur’an perespektip madzahibul arba’ah adalah salah satu asas pokok hidup yang paling penting dalam pergaulan atau masyarakat yang sempurna. Pernikahan bukan saja merupakan satu jalan untuk mengatur kehidupan rumah tangga dan keturunan, lebih dari itu pernikahan adalah jalan menuju pintu (ta’aruf) perkenalan antara suatu kaum dengan kaum yang lain.
Untuk membanguna rumah tangga yang sakinah, sejahtera dan kokoh, suatu rumah tangga perlunya dihiasi dengan cinta dan kasih sayang, serta mempunyai prinsip bijaksana dan rasa saling mengerti satu sama lain antara suami-istri. Hal tersebut bisa dicapai apabila masing-masing diantara suami dan istri mampu melakukan kewajiban dangan memperoleh hak dari pasangannya.
Mahar termasuk keutamaan agama Islam dalam melindungi dan memuliakan para kaum perempuan dengan memberikan hak yang dimintanya dalam pernikahan berupa mahar perkawinan yang besar kecilnya ditetapkan atas persetujuan kedua belah pihak karena pemberian itu harus diberikan secara ikhlas. Mahar pernikahan diberikan pihak mempelai laki-laki kepada mempelai perempuan pada saat perkawinan. Dalam perkawinan di Indonesia biasanya digunakan sebagai mahar berupa materi atau harta. Akhir-akhir ini menjadi nge-tren hafalan al-Qur’an sebagai media mahar pernikahan, disebabkan berbagai alasan untuk meringankan mahar dan juga atas inisiatif pribadi. Kasus yang terjadi sekarng tidak sama historis sahabat Sahl bin Said al-Sa’idi. Maka perlu dikaji dangan prespektif hukum Islam dan maqasid al-syari’ah. Sedangkan dalam penelitian ini merupakan teori kepustakaan (library research) dengan menggunakan pendekatan metodologi deskriptif analisis.
El Papel del Capital Intelectual en la Innovación de Productos y Procesos y el Desempeño de las Pymes
Authors: Beltramino Nicolás 
Published: March 2022

The aim of this study is to analyse the effects of the components of intellectual capital (human capital, structural capital and relational capital) on the innovation capacity, both in products and processes, of industrial SMEs. In turn, to analyse the effect of product and process innovation on performance. A study was carried out on a sample of 259 industrial SMEs in the province of Córdoba, Argentina. The data was analyzed through Structural Equation Modeling, using the Smart PLS software. The results show firstly that the constructions used by the model are valid and reliable. The study provides evidence that the constructs Intellectual Capital, Human Capital, Structural Capital and Relational Capital have significant and positive effects on innovation in products and processes, in the context of the analyzed sample. While analyzing the effect of product and process innovation on performance, it was found that there is a positive and significant relationship of process innovation to performance, while product innovation shows a positive but not significant relationship.

Reception date: March 9, 2019 Acceptance date: August 18, 2019
Estrategia Tecnológica y Organización del Trabajo: Especificidades de la Industria Manufacturera Argentina
Authors: Erbes Analía , Roitter Sonia 
Published: March 2022

Technological strategy of the companies and the different aspects of work organization contribute to the specificity and potential for incorporation of new technologies in the Argentine industry. In order to study the relationship between technological strategies and the characterizing features of work organization in industrial companies, information from the National Survey of Employment and Innovation Dynamics for industrial companies in Argentina 2010-2012 is analyzed. It is concluded that the development of more complex technological strategies requires work organization structures and processes where learning plays a key role.

Date received: March 19, 2020 Acceptance date: May 28, 2020
FAKTOR - FAKTOR YANG BERHUBUNGAN DENGAN PENGELOLAAN SAMPAH RUMAH TANGGA DI KELURAHAN SANUA KOTA KENDARI TAHUN 2018
Authors: Rachman Ranno Marlany , Sya’ban Abdul Rahim , Setiawan Tri Agus 
Published: March 2022

ABSTRAKData Dinas Kebersihan Kota Kendari Tahun 2016 Kecamatan Kendari Barat memproduksi sampah 32,85 ton/hari, sedangkan di tahun 2017 mengalami peningkatan 12 m3/hari, dan jumlah sampah yang ditangani/diangkut ke Tempat Pembuangan Akhir (TPA) sebanyak 7 m3/hari, sampah yang dihasilkan adalah sampah rumah tangga dan sampah dari Pasar Sentral Kota Kendari. Jenis penelitian ini adalah observational dengan desain cross sectional study. Penelitian ini bertujuan untuk mengetahui hubungan antara pengetahuan, tindakan dan sarana prasarana dengan pengelolaan sampah rumah tangga pada masyarakat Kelurahan Sanua Kota Kendari Tahun 2018. Jumlah populasi adalah 983 orang responden, dengan teknik penarikan sampel menggunakan teknik cluster random sampling, dengan jumlah sampel 91 orang responden. Hasil penelitian menunjukkan bahwa ada hubungan antara pengetahuan dengan pengelolaan sampah dengan nilai x2 hitung = 10.812 > x2 tabel =2.784 dan hasil ᵠ= 0,345 yang berada pada level lemah. Ada hubungan antara tindakan dengan pengelolaan sampah dengan nilai x2 hitung = 11.065 > x2 tabel = 2.784 dan hasil ᵠ= 0,349 yang berada pada level lemah. Ada hubungan antara sarana prasarana dengan pengelolaan sampah dengan nilai x2 hitung = 36.107 > x2 tabel = 2.784 dan hasil ᵠ= 0,630 yang berada pada level kuat. Kata Kunci : Pengelolaan Sampah, Pengetahuan, Tindakan, Sarana PrasaranaABSTRACTData from the Kendari City Sanitation Office in 2016 in West Kendari sub-district produced 32.85 tons/day of waste, while in 2017 it increased by 12 m3 / day, and the amount of waste handled/transported to the Final Disposal Site (TPA) was 7 m3 / day, The garbage produced is household waste and rubbish from the Kendari City Central Market. This type of research is an observational cross-sectional study design. This study aims to determine the relationship between knowledge, actions and infrastructure and household waste management in the community of Sanua Kelurahan, Kendari City in 2018. The population is 983 respondents, with a sampling technique using cluster random sampling techniques, with a total sample of 91 respondents. The results showed that there was a relationship between knowledge and waste management with the calculated x2 value = 10,812> x2 table = 2,784 and the result ᵠ = 0.345 at the weak level. There is a relationship between actions with waste management with the calculated x2 value = 11,065> x2 table = 2,784 and the result ᵠ = 0.349 which is at a weak level. There is a relationship between infrastructure and waste management with the calculated x2 value = 36,107> x2 table = 2,784 and the result ᵠ = 0.630 which is at a strong level. Keywords : Waste Management, Knowledge, Actions, Infrastructure Facilities
INVESTIGASI PARAMETER PENETRASI ASPAL PEN 60/70 YANG DIMODIFIKASI DENGAN DAMAR
Authors: One La , Haruzin Ased , Udo M. Al Ikram , Parizia M. Tommy Al 
Published: March 2022

ABSTRAK Pemanfaatan biometerial sebagai bahan konstruksi jalan merupakan salah satu penelitian inovasi dalam mendukung pembangunan berkelanjutan pada sektor transportasi. Penelitian ini bertujuan untuk menganalisis pengaruh penggunaan damar terhadap penetrasi aspal modifikai , dan untuk menemukan seberapa banyak penggunaan damar sebagai material substitusi aspal sehingga memenuhi persyaratan penetrasi sesuai ketentuan SNI. Persentase Damar yang digunakan sebagai bahan modifikasi antara 2.5%-10% terhadap berat total aspal modifikasi dengan interval 2,5%. Jenis damar yang digunkan adalah damar mata kucing dan aspal minyak yang digunakan adalah aspal pen 60/70. Pengujian penetrasi mengacu pada SNI 06-.2456-199. Alat yang digunakan adalah penetrometer. Hasil penelitian menunjukan bahwa nilai penertrasi aspal modifikasi pada kadar damar 2,5%, 5%, 7,5%, dan 10% secara berturut-turut adalah 65, 64, 63, 52, dan 48. Penggunaan Damar sebagai substitusi Aspal Minyak hingga 5,4% masih dalam rentang persyaratan spesifikasi yakni 60-70 (dmm). Kata Kunci : Damar, Aspal Pen 60/70, PenetrasiABSTRACT The use of biomaterials as a road construction material is one of the research innovations in supporting sustainable development in the transportation sector. This study aims to analyze the effect of the usage of damar on the penetration of modified asphalt, to find out how much damar which used as an asphalt substitution material that meets the penetration requirements according to the provisions of SNI, and to find the equation model of damar content and penetration relationship. The Damar content used as a modified material is between 0% -10% of the total weight of Modified Asphalt with an interval of 2.5%. The type of Damar used is Cat's Eye Damar, and the Petroleum Asphalt used is Penetration Asphalt - 60/70. The penetration testing uses a penetrometer and refers to SNI 06-.2456-199. The results showed that the penetration value of Modified Asphalt is 65, 64, 63, 52, and 48 mm by correspondings to Damar content of 0%, 2,5%, 5%, 7,5%, and 10%. The use of damar content up to 5,4% as a substitute for Petroleum Asphalt is still within the range of SNI specification requirements, namely 60-70 (0,1 mm). Keywords : Damar, Petroleum Asphalt, Penetration
Pengaruh Motivasi Wisatawan Domestik terhadap Minat Kunjung ke Kuta Mandalika
Authors: Herman  , Savira Wira Putri  
Published: March 2022

Latar belakang:
Sektor pariwisata ditetapkan sebagai sektor unggulan untuk dikembangkan secara sinergi. Melalui pendekatan pariwisata berkelanjutan (sustainable tourism) perlu sinergi antara upaya pelestarian alam, budaya, beserta fasilitas penunjang pelayanan wisatawan dalam pembangunan pariwisata nasional
Methodology:
Penelitian ini menggunakan metode deskriptif kuantitatif. Populasi dalam penelitian ini adalah seluruh wisatawan domestik yang berkunjung ke Kuta Mandalika. Metode penentuan sampel dalam penelitian ini adalah non-probability sampling sebanyak 100 responden. Pengumpulan data dilakukan teknik observasi, dokumentasi dan penyebaran kuesioner. Analisa data menggunakan uji validitas dan uji reliabilitas beserta analisis regresi sederhana sebagai alat untuk menguju kebenaran hipotesis.
Hasil:
Hasil penelitian ini menunjukkan bahwa : (1) motivasi fisik wisatawan domestik terhadap minat kunjung berpengaruh sebanyak 7,2%, (2) motivasi budaya wisatawan domestik terhadap minat kunjung berpengaruh sebanyak 4,5%, (3) motivasi individu wisatawan domestik terhadap minat kunjung berpengaruh sebanyak 0,5% dan (4) motivasi status dan prestise wisatawan domestik terhadap minat kunjung berpengaruh sebanyak 1,8%.
Kesimpulan:
Berdasarkan penilaian dari responden mengenai Variabel Motivasi Status dan Prestise (X4) dengan item-item kegiatan menunjukkan kerabat bahwa pernah mengunjungi suatu tempat yang baru, menghadiri konferensi, menambah wawasan dan melakukan penelitian akademis dinilai baik oleh 100 responden yang merupakan wisatawan domestik Kuta Mandalika dimana dapat dilihat dari analisis frekuensi yang memperoleh nilai sebesar 3,73 dan hanya memiliki pengaruh sebesar 1,8% terhadap minat kunjung wisatawan domestik.