bluuebunny/crossref_metadata_2025_split huggingface dataset:
Direct oral anticoagulant agents attenuate temporary aortic occlusion-induced renal oxidative and inflammatory responses in rats
Authors: Durmaz Selim , Kurtoğlu Tünay , Faruk Rahman Ömer , Tataroğlu Canten , Yılmaz Mustafa , Barbarus Emin , Hüseyin Erkan Muhammet 
Published: August 2022

Background: This study aims to investigate the effects of different direct oral anticoagulants on experimental renal injury induced by temporary infrarenal aortic occlusion.
Methods: A total of 35 male Wistar rats (250 to 350 g) were randomly allocated to any of the five groups: sham, ischemia-reperfusion, rivaroxaban, dabigatran, and apixaban groups. Sham group underwent median laparotomy. Ischemia-reperfusion group was given saline gavage for one week. Animals in the other groups received rivaroxaban (3 mg/kg), dabigatran (15 mg/kg), or apixaban (10 mg/kg) daily once for one week via oral gavage. The infrarenal abdominal aorta was clamped for 60 min, and reperfusion was maintained for 120 min in the ischemia-reperfusion, rivaroxaban, dabigatran, and apixaban groups. At the end of reperfusion, kidneys were harvested for biochemical and histopathological analysis.
Results: Renal total antioxidant capacity was reduced, and total oxidant status, interleukin-1 beta, and tumor necrosis factor-alpha were elevated in the ischemia-reperfusion group, compared to the sham group (p<0.005). Histological damage scores were also higher in the ischemia-reperfusion group (p<0.005). Administration of direct oral anticoagulants caused an increase of total antioxidant capacity and reduction of total oxidant status, tumor necrosis factor-alpha, and interleukin-1 beta in the rivaroxaban, dabigatran, and apixaban groups compared to the ischemia-reperfusion group (p<0.005). Histological damage scores were lower in the rivaroxaban and dabigatran groups than the ischemia-reperfusion group scores (p<0.005).
Conclusion: Direct oral anticoagulants reduce aortic clamping-induced renal tissue oxidation and inflammation. Rivaroxaban and dabigatran attenuate ischemia-reperfusion-related histological damage in kidneys.
Outcomes of patients with left ventricular assist device infected with SARS-CoV-2
Authors: Kahraman Ümit , Güneş Ergi Defne , Yağmur Burcu , Engin Çağatay , Yağdı Tahir , Nalbantgil Sanem , Özbaran Mustafa 
Published: August 2022

Background: The aim of this study was to describe clinical characteristics, course, and outcomes of the novel coronavirus disease 2019 (COVID-19) in heart failure patients with left ventricular assist device.
Methods: Between November 2020 and August 2021, a total of 20 patients (18 males, 2 females; mean age: 57.0+10.0 years; range, 30 to 71 years) with left ventricular assist device and who were diagnosed by the COVID-19 polymerase chain reaction testing were included. For each patient, disease-related factors were evaluated including presence of hospitalization, home quarantine, presence of lung damage, antiviral medication strategy, symptomatology and complications following COVID-19.
Results: Seven patients 35% patients died in our cohort following the COVID-19. All these patients experienced variety of complications following COVID-19 including subarachnoid hemorrhage and right heart failure. Three patients were already hospitalized due to COVID-19 and decompensated progressively, resulting in death on Days 14, 4, and 7 after the initial diagnosis.
Conclusion: COVID-19 seems to be an important cause of mortality in patients with LVAD who have borderline cardiopulmonary function. Great care should be taken to avoid interruption in routine follow-ups with these patients, since they present a more sensitive population.
Predictors of pulmonary hypertension after atrial septal defect closure: Impact of atrial fibrillation
Authors: Çelik Mehmet , Yılmaz Yusuf , Küp Ayhan , Kahyaoğlu Muzaffer , Karagöz Ali , Özdemir Nihal , Kaymaz Cihangir , Kaan Kırali Mehmet 
Published: August 2022

Background: In this study, we aimed to evaluate the course of pulmonary artery systolic pressure, to identify factors associated with pulmonary arterial hypertension, and to determine the impact of atrial septal defect closure on clinical outcomes in long-term follow-up.
Methods: Between March 2008 and August 2020, a total of 547 adult patients (193 males, 354 females; median age: 37 years; range, 27.5 to 47 years) with secundum atrial septal defect were retrospectively analyzed. Of these patients, 304 underwent percutaneous defect closure and 243 underwent isolated surgical repairs. Pulmonary arterial hypertension was defined as a noninvasively estimated pulmonary artery systolic pressure of ?40 mmHg at the final follow-up after atrial septal defect closure. Factors associated with pulmonary arterial hypertension were analyzed.
Results: Sixty-nine (12.6%) patients presented with pulmonary arterial hypertension at the final follow-up. A total of 35 (6.4%) patients had persistent atrial fibrillation before atrial septal defect closure, and 22 of these 35 patients had pulmonary arterial hypertension during long-term follow-up. Older age at the time of atrial septal defect closure (HR: 4.76; 95% CI: 2.68-8.44; p<0.001), the presence of persistent atrial fibrillation (HR: 2.18; 95% CI: 1.21-3.91; p=0.009), and greater right ventricular basal diameter (HR: 4.78; 95% CI: 2.57-8.84; p<0.001) were found to be associated with late pulmonary arterial hypertension.
Conclusion: The presence of persistent atrial fibrillation may be used to predict patients at higher risk for pulmonary arterial hypertension after atrial septal defect closure.
Patient Readiness for Hospital Discharge
Authors: Li Na , GUO Manjie , YOU Simeng , JI Hong 
Published: August 2022

Background: With the development of the "person-centered" model of nursing care, for a better understanding of patient self-reported Readiness for Hospital Discharge (RHD) the theme is being studied extensively by researchers and professionals around the world.
Methods: Using search terms such as "readiness for hospital discharge", (RHD) we systematically searched the PubMed database for relevant articles on patients with RHD from 2019 to the present. Screening was performed strictly according to the inclusion and exclusion criteria, and finally, the relevant literature was read and summarized.
Results: A total of 8 articles met the criteria published between 2019 and 2022. The probability of being unprepared for discharge varied by disease type. Factors influencing patient RHD included demographic characteristics, psychological status, disease-related information, and hospital setting factors.
Conclusions: Studies of RHD patients have been extensively developed in recent years. There is evidence to sustain that some patients leave the hospital unprepared, and in conditions that would require further attention of clinical staff. The issue may not be receiving the best required attention in what should be a priority of healthcare management and concern with impacts on the patients’ quality of life.
Contribution to Evidence-Based Care: The article contributes to an update on how to identify patients with low RHD in the context of busy nursing workloads and make clear interventions, thus improving the efficiency of nursing care. In addition, according to the factors affecting patients' RHD, scientific discharge plans were constructed and used clinically to promote the application of nursing research results in nursing practice. Finally, the article sustains taht evidence-based nursing care can ensure better quality ofcare and contribute to the improvement of impacts on patients' quality of life.
SEMANGAT INTERNASIONALITAS SERIKAT MARIA MONTFORTAN DALAM MELAKSANAKAN KARYA MISI GEREJA
Authors: Vinsensius Rixnaldi Masut  , Antonius Denny Firmanto  , Nanik Wijiyati Aluwesia  
Published: August 2022

Studi ini bertujuan untuk menjelaskan semangat internasionalitas Serikat Maria Montfortan (SMM) dalam surat edaran Superior Jendral SMM, Pater William Considine. Semangat internasionalitas yang ditegaskan Pater William Considine merupakan bentuk tanggapan SMM atas seruan Gereja dalam Konsili Vatikan II tentang karya misioner, khususnya dalam Dekrit Ad Gentes yang mengulas banyak tentang karya misioner Gereja di dunia. Serikat Maria Montfortan sebagai sebuah kongregasi misi internasional mempunyai andil yang besar dalam mensukseskan misi Gereja ini. Di bawah payung spiritualitas internasional, ia mengajak seluruh anggota Serikat untuk membuka mata terhadap situasi konkret dunia, lalu mengambil langkah pasti berupa perutusan misionaris sebagai bentuk aksi nyata atas misi Ad Gentes Gereja. Metodologi yang digunakan dalam studi ini ialah metode kualitatif dengan melakukan pembacaan kritis atas Dokumen Ad Gentes dan Surat Edaran Pater William Considine. Kedua dokumen ini kemudian dibaca dalam situasi dunia masa kini yang menghadapi banyak perubahan multidimensi yang kompleks. Temuan dari studi ini ialah: (1) Serikat Maria Montfortan sebagai bagian dari kongregasi internasional dipanggil untuk berpartisipasi aktif dalam karya misi Gereja untuk mewartakan Kabar Gembira Kristus kepada semua bangsa. (2) Tujuan ini dapat tercapai jika semua anggota SMM kembali menghidupkan semangat internasionalitas sebagaimana yang diserukan oleh Pater William Considine.
IMPLEMENTASI KOMPETENSI PEDAGOGIK GURU PENDIDIKAN AGAMA KATOLIK DI SEKOLAH MENENGAH PERTAMA
Authors: Paulinus Tibo, Lasmalum Sitohang  
Published: August 2022

Tujuan penelitian ini untuk mengetahui implementasi kompetensi pedagogik Guru Pendidikan Agama Katolik dalam membentuk minat belajar peserta didik di Sekolah Menengah Pertama Negeri 2 Parbuluan. Permasalahan penelitian ialah bagaimana minat belajar peserta didik dan implementasi kompetensi pedagogik Guru Pendidikan Agama Katolik. Metode penelitian ini adalah metode kualitatif. Data dikumpulkan dengan teknik wawancara, observasi dan dokumentasi. Informan peneliti adalah Guru Pendidikan Agama Katolik, Kepala Sekolah, guru sejawat dan peserta didik. Untuk mengukur keabsahan data penelitian maka peneliti melakukan triangulasi baik teknik dan sumber. Hasil penelitian menunjukkan bahwa peserta didik sudah memiliki minat dalam pembelajaran Pendidikan Agama Katolik, terlihat dari implementasi kompetensi pendagogik yang dilaksanakan sudah terlaksana dengan baik oleh Guru Pendidikan Agama Katolik.
Philippe de Mézières et Pierre de Thomas : amitié, émotions, et sainteté au XIVe siècle
Authors: Blumenfeld-Kosinski Renate 
Published: August 2022

Cet article explore l’amitié entre l’homme saint Pierre de Thomas (1305-1366), Carmélite, diplomate, et patriarque de Constantinople et son biographe plus jeune, Philippe de Mézières (1327-1405) écrivain, conseiller royal et penseur politique célèbre. Une analyse du vocabulaire émotif montre que le texte de la Vie de Saint Pierre de Thomas (1366) s’inscrit dans une tradition biblique (les Cantiques) et classique de l’amitié. Ce qui nous intéresse ici c’est comment l’expression des émotions (réelles ou gouvernées par des formules – ou les deux ?) donne une forme au récit hagiographique qui distingue ce texte des productions hagiographiques contemporaines et offre un modèle de sainteté qui se détache en partie de la tradition. L’analyse se concentre sur une sélection de scènes particulièrement émouvantes : leur première rencontre lors d’une épidimie de la peste en Chypre; la mort de Pierre de Thomas et son apparition comme revenant.
De la narration à la scène : l’amitié à l’épreuve du malheur dans Marc-Antoine et Bradamante de Robert Garnier
Authors: Dobby-Poirson Florence 
Published: August 2022

Garnier met en scène plusieurs personnages d’amis. Ils lui sont inspirés par des récits épiques ou historiques, où l’amitié contribue peu ou prou au mouvement dramatique de la narration. Il confère ainsi à une figure d’arrière-plan un véritable rôle théâtral, ou transpose sur scène une situation dramatique déjà existante dans le texte-source : dilemme, reconnaissance, suicide. Confrontés au malheur, les personnages prouvent leur dévouement aux affligés en leur apportant leur soutien moral, ou une aide effective qui fait rebondir l’action. Ces scènes topiques comportent parfois elles-mêmes des récits, qui éclairent le public sur la naissance de l’amitié, les expériences, les sentiments et les valeurs qui la fondent : admiration pour le courage, la loyauté de l’ami, gratitude pour son esprit de sacrifice.
AAPM MEDICAL PHYSICS PRACTICE GUIDELINE 5.b: Commissioning and QA of treatment planning dose calculations—Megavoltage photon and electron beams
Authors: Geurts Mark W. , Jacqmin Dustin J. , Jones Lindsay E. , Kry Stephen F. , Mihailidis Dimitris N. , Ohrt Jared D. , Ritter Timothy , Smilowitz Jennifer B. , Wingreen Nicholai E. 
Published: August 2022

AbstractThe American Association of Physicists in Medicine (AAPM) is a nonprofit professional society whose primary purposes are to advance the science, education, and professional practice of medical physics. The AAPM has more than 8000 members and is the principal organization of medical physicists in the United States. The AAPM will periodically define new practice guidelines for medical physics practice to help advance the science of medical physics and to improve the quality of service to patients throughout the United States. Existing medical physics practice guidelines will be reviewed for the purpose of revision or renewal, as appropriate, on their fifth anniversary or sooner. Each medical physics practice guideline represents a policy statement by the AAPM, has undergone a thorough consensus process in which it has been subjected to extensive review, and requires the approval of the Professional Council. The medical physics practice guidelines recognize that the safe and effective use of diagnostic and therapeutic radiology requires specific training, skills, and techniques, as described in each document. Reproduction or modification of the published practice guidelines and technical standards by those entities not providing these services is not authorized. The following terms are used in the AAPM practice guidelines:

Must and Must Not: Used to indicate that adherence to the recommendation is considered necessary to conform to this practice guideline. While must is the term to be used in the guidelines, if an entity that adopts the guideline has shall as the preferred term, the AAPM considers that must and shall have the same meaning.
Should and Should Not: Used to indicate a prudent practice to which exceptions may occasionally be made in appropriate circumstances.
Adaptive control for synchronization of semi‐linear complex spatio‐temporal networks with time‐invariant coupling delay and time‐variant coupling delay
Authors: Yang Chuanhai , Yang Yuqian , Yang Chengdong , Zhu Jie , Zhang Ancai , Qiu Jianlong 
Published: August 2022

SummaryThis article studies the adaptive control for synchronization of semi‐linear complex spatio‐temporal networks (CSNs). And the leader‐following and leaderless CSN with time‐invariant coupling delay and time‐variant coupling delay are developed separately from two aspects. The adaptive control strategies are proposed to reach the asymptotic convergence of synchronization error. Synchronization criteria and sufficient conditions are obtained for the leader‐following CSN error model and leaderless CSN error model by constructing the apposite Lyapunov–Krasovskii functions and applying Wirtinger's inequality. Finally, two experimental examples are given to verify the feasibility of the theories proposed in this article.
A design of disturbance observer in frequency domain for robust control of time delay system
Authors: Kim Jong‐Ryong , Yun Jong‐Nam 
Published: August 2022

SummaryThe disturbance observer (DOB) based robust control is widely used to suppress the effect of model uncertainty and disturbances. Improvement of disturbance suppression performance in DOB based control (DOBC) is achieved by expansion of the Q‐filter's bandwidth or equivalently increment of its cutoff frequency. However, if the system has time delay property, the bandwidth cannot be arbitrarily extended because of the stability demand of the closed loop system. Although the Q‐filter's bandwidth is restricted, there is still room for improving disturbance suppression performance by elaborately designing the Q‐filter's structure and coefficients. For the optimized design of Q‐filter, at the beginning of this paper, based on the analysis of the model uncertainty due to time delay and its upper bound, a new robust stability condition of closed loop system is derived as a type of inequality on complementary sensitivity function of whole closed loop system with DOB. Then a mixed sensitivity optimization problem for optimizing disturbance suppression performance under this stability condition is formulated with structural constraint. Finally, in order to solve this optimization problem, pseudo loop factorization and shaping method is used to transform it into standard control problem without the structural constraint so that it can be solved systematically. The results of illustrative examples and simulations validate the effectiveness of the proposed method.
Maximizing Merits of Undesirable δ‐FAPbI3 by Constructing yellow/black Heterophase Bilayer for Efficient and Stable Perovskite Photovoltaics
Authors: Zhang Jiafeng , Jiang Xiaoqing , Liu Xiaotao , Guo Xin , Li Can 
Published: August 2022

AbstractYellow‐phase formamidinium lead iodide (δ‐FAPbI3) as a degradation product of black perovskite phase is usually unwelcome in perovskite solar cells (PSCs). However, it also shows high potential in passivating defects and protecting perovskite films from moisture intrusion due to its water‐stable nature. Herein, the utilization of δ‐FAPbI3 to construct a yellow/black heterophase bilayer is reported, in which the perovskite layer is shielded by in situ formed δ‐FAPbI3 species on the surface, for PSCs with enhanced efficiency and stability. It is found that the δ‐FAPbI3 layer with a broader bandgap than the black‐phase perovskite can efficiently suppress the charge recombination at the interface, offering a high PSC efficiency of 23.10%. More importantly, the δ‐FAPbI3‐modified devices exhibit preferable stability against various external stresses to that of the control ones. Compared to those using the disliked δ‐FAPbI3 in the literature, the strategy, which maximizes its merits in reducing the interfacial charge recombination and stabilizing the perovskite structure, is more simple yet effective to realize highly efficient and stable PSCs.
A Vascular Graft On‐a‐Chip Platform for Assessing the Thrombogenicity of Vascular Prosthesis and Coatings with Tuneable Flow and Surface Conditions
Authors: Bot Veronica A. , Shakeri Amid , Weitz Jeffrey I. , Didar Tohid F. 
Published: August 2022

AbstractVascular grafts are essential for the management of cardiovascular disease. However, the lifesaving potential of these devices is undermined by thrombosis arising from material and flow interactions on the blood contacting surface. To combat this issue, antithrombogenic coatings have emerged as a promising strategy for modulating blood and graft interaction in vivo. Although an important determinant of graft performance, hemodynamics are frequently overlooked for in vitro testing of coatings and their translatability remains poorly understood. Herein, this limitation is addressed with a microscale graft on‐a‐chip platform incorporating vascular prosthesis and coatings with tuneable flow and surface conditions in vitro. As a proof of concept, the platform is used to test the thrombogenicity of a novel class of lubricant‐infused surface (LIS) and antibody lubricant‐infused (anti‐CD34 LIS) coated expanded polytetrafluoroethylene (ePTFE) vascular grafts in the presence of arterial wall shear stress with and without endothelial cells. The findings suggest LIS ePTFE is thromboresistant under flow with significantly reduced fibrin(ogen) deposition, thrombin activity, and blood cell adhesion compared to uncoated controls. It is moreover apparent that the microscale properties of the device are advantageous for the testing and translation of novel antithrombogenic coatings and blood‐contacting materials in general.
Betulin Self‐Assembly: From High Axial Aspect Crystals to Hedgehog Suprastructures
Authors: Niu Xun , Foster E. Johan , Patrick Brian O. , Rojas Orlando J. 
Published: August 2022

AbstractBetulin is introduced as a building block of supramolecular structures that form by noncovalent interactions. Betulin, an abundant triterpene, is first extracted from birch bark to self‐assemble into hierarchical crystalline structures. Following a direct bottom‐up process, solvatomorphs of betulin‐2‐propanol form high axial aspect microparticles, 100–300 µm in length, and lateral sizes in the 15–40 µm range. Under sonication, the microparticles evolve into 3D hedgehog suprastructures (15–30 µm in size) comprising a core (3–5 µm diameter) with connected spines (200–300 nm in width). Depending on the intensity of the delivered energy, the associated morphogenesis starts with metastable aggregates that undergo dislocation, solvent migration, and radial growth. It is found that the formed spherulite‐like, hedgehog structures are a consequence of residual solvent diffusion, leading to crystallites with oriented attachment on specific planes. These results add to the design of structures from natural building blocks, which are expected to deliver functions encoded in the respective morphology. Owing to the unique features of betulin supraparticles, they develop surface architectures, for instance, in superhydrophobic coatings, which are shown to exhibit exceptional repellency and surface mechanical strength, as tested on various substrates.
Two‐Dimensional Organometallic Frameworks with Pyridinic Single‐Metal‐Atom Sites for Bifunctional ORR/OER
Authors: Liu Tianyang , Wang Yu , Li Yafei 
Published: August 2022

AbstractAchieving efficient bifunctional oxygen reduction and evolution reactions (ORR/OER) on non‐noble metal catalysts is desirable but remains a significant challenge. Herein, inspired by the experimentally synthesized (phen2N2)FeCl molecule, a stable 2D organometallic framework, namely (phen2N2)FeCl monolayer, is proposed as a qualified candidate by means of constant‐potential first‐principles computations. Unlike most 2D organometallic frameworks that feature pyrrolic coordination, the (phen2N2)FeCl monolayer exhibits a pyridinic‐type FeN4 ligation environment. The unique structure of the monolayer enables a high single‐atom Fe loading in a heterogeneous system, superior to the typical FeNC materials. Constant‐potential energy analysis and microkinetic modeling demonstrate that the monolayer holds great potential for facilitating bifunctional ORR/OER in both the acidic and alkaline conditions, showing theoretical activity higher than the FeNC materials, (phen2N2)FeCl molecule, and Pt/IrO2. Moreover, (phen2N2)MCl monolayers (M = Mn, Co, and Ni) are explored, and the (phen2N2)MnCl monolayer is also identified to have excellent bifunctional activity. This study highlights the rational design of local coordination environments for boosting the electrocatalytic performance of 2D organometallic frameworks.