bluuebunny/crossref_metadata_2025_split huggingface dataset:
Types of Severe Convective Wind Events in Eastern Australia
Authors: Brown Andrew , Dowdy Andrew , Lane Todd P. , Hitchcock Stacey 
Published: November 2022

Abstract
Severe winds associated with thunderstorms and convection are a hazard affecting key aspects of society, including emergency management and infrastructure design. Several studies around the world have shown that severe convective winds (SCWs) can occur due to several different processes, in a range of atmospheric environments, with significant regional and temporal variations. However, in eastern Australia, the types of SCWs and their variability have not been assessed outside of individual case studies. Here, a combination of reanalysis, lightning, radar, and station data are used to characterize a set of 36 SCW events in four locations in eastern Australia. These events are objectively chosen based on the strongest measured wind gusts from station data (greater than 25 m s−1) over a 14-yr period, with 6-hourly lightning data and a 30-dBZ radar reflectivity threshold used to infer moist convective processes. Radar data analysis suggests that these SCW events are produced by several different types of parent thunderstorms, with station observations suggesting a range of temporal characteristics for these different event types. A clustering algorithm applied to environmental data is used to suggest three dominant types of events, based on low-level moisture, low-level temperature lapse rate, and deep-layer mean wind speed and vertical shear. Based on the distribution of synoptic conditions and thunderstorm properties for each environmental cluster, it is suggested that these three event types correspond to the following: 1) shallow vertical transport of strong synoptic-scale winds to the surface, 2) downbursts driven by subcloud evaporation, and 3) intense thunderstorms including supercells.

Significance Statement
The purpose of this study is to better understand the different types of severe wind events in eastern Australia that are produced by convective storms. We looked at 36 historical cases in four locations and find that severe winds can be produced by very different classes of convective storms. We also suggest that there are three key types of atmospheric environment that are associated with events in this region. These environments vary in terms of the vertical structure of temperature, moisture, and wind speed above the surface. Understanding the different types of environments that lead to severe convective winds can help to reduce uncertainties in future climate projections for this region based on environmental changes.
Strong Relationship between Eye Radius and Radius of Maximum Wind of Tropical Cyclones
Authors: Tsukada Taiga , Horinouchi Takeshi 
Published: November 2022

Abstract
Estimation of the radius of maximum wind (RMW) of tropical cyclone (TC) is helpful for the disaster prevention and mitigation. If RMWs are estimated from infrared (IR) imagery taken by geostationary meteorological satellites, their estimation is available densely in time, regardless of the ocean basin. Kossin et al. showed that when TCs have clear eyes, the eye radii estimated from IR images have a high correlation with the RMW estimated from aircraft reconnaissance. The regression of the former onto that latter was shown to have a mean absolute error (MAE) of 4.7 km. We revisit the IR-based RMW estimation by using C-band synthetic aperture radar (SAR) sea surface wind estimates. The criteria for selecting clear-eye cases are simplified. The MAE of the Kossin et al. method is found to be smaller than previously suggested: 3.1 km when the proposed relation is used and 2.7 km when the regression is revised with the SAR-measured RMWs. We further propose an improvement of the IR-based method to estimate the eye radii. The resultant MAE is shown to be 1.7 km, which indicates that the IR-based RMW estimation is more accurate than has been suggested. A strong correlation between eyewall slope and eye size is confirmed. We also investigated cloud features in the eye that may be closely related to RMW and wind structure around RMW. Potential applications of highly accurate RMW estimation are discussed.

Significance Statement
The radius of maximum wind (RMW) of tropical cyclone (TC) is an important factor for TC intensity estimation and disaster prevention. A previous study suggested that the RMWs of TCs with clear eyes can be estimated from geostationary satellite images at a mean absolute error (MAE) of 4.7 km. Here we improved the method, reducing the MAE by more than one-half. Since the method does not require aircraft or satellite in low Earth orbit, it helps TC monitoring at high frequency. The method can also improve initialization of models used to predict TC hazards and further our physical understanding and the climatology of the wind structures near the centers of TCs.
Daily Physical Activity: Associations With Memory and Affect
Authors: Kompf Justin M. , Lachman Margie E. 
Published: November 2022

Purpose Little is known about effects of moderate to vigorous physical activity (MVPA) and resistance training on daily variations in memory and affect. This study examined the relationship of MVPA and resistance training to memory and affect in daily life. Design Short-term longitudinal 7-day diary. Setting Northeast; primarily Boston-area communities. Sample Adults aged 25 to 94. Measures For seven days, MVPA was assessed with an Actigraph. and resistance training was self-reported. Each evening, memory failures, positive and negative affect were recorded in a written diary and objective memory performance was assessed by telephone. Analysis Multilevel linear regression analyses examined the between and within person associations of MVPA and resistance training with memory performance, memory failures, and affect. Results Those who engaged in more MVPA had better memory performance across the week (b = 0.0163, SE = 0.0076, f2 = 0.004, p = 0.033). Participants reported higher levels of positive affect on days in which they spent more time in MVPA than usual (b = 0.003, SE = 0.001, f2 = 0.144, p < .001) and on days they engaged in resistance training (b = 0.1547, SE = 0.079, f2 = 0.007; p = 0.049). Conclusions Those who spent more time in MVPA had better memory performance, and on days with greater than usual MVPA time and resistance training, affect was more positive than on days with less activity. Implications for motivating physical exercise are considered.
“N-Acetylcysteine for Obsessive-Compulsive and Related Disorders in Children and Adolescents: A Review”
Authors: Parli Gabrielle M. , Gales Mark A. , Gales Barry J. 
Published: November 2022

Objective: To evaluate clinical data using oral n-acetylcysteine (NAC) in obsessive-compulsive and related disorders (OCDRD) treatment. Data Sources: PubMed, Ovid MEDLINE (1946-July 2022), and the Cochrane Library database were searched using the terms NAC, children, adolescent, obsessive-compulsive disorder (OCD), trichotillomania (TTM), excoriation, hoarding disorder, and body dysmorphic disorder. Bibliographies were reviewed for relevant trials and case studies. Study Selection and Data Extraction: English language, clinical trials, or case studies analyzing NAC use in patients aged 3 to 21 years old with OCDRD as determined by the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition. Data Synthesis: Three randomized double-blind placebo-controlled trials of NAC in children and adolescents studied 121 patients with OCDRD. Trials assessed symptom severity from baseline to 10 to 12 weeks of NAC therapy. Two OCD trials identified statistically significant improvements, with only 1 trial demonstrating a clear clinically relevant difference from placebo. One trial in TTM found no difference between the NAC and placebo. Adverse effects were mild and included nausea, blurred vision, fatigue, tremor, and sweats. N-acetylcysteine titrated to 2400 or 2700 mg/day in divided doses was the most studied regimen. Relevance to Patient Care and Clinical Practice: Many OCDRD patients fail to completely respond to first-line treatment with cognitive behavioral therapy (CBT) and/or selective serotonin reuptake inhibitors (SSRIs) leaving practitioners with few additional treatment options. Preliminary efficacy and safety data are presented in this review. Conclusions: Limited evidence suggests children and adolescents with OCD refractory to SSRIs or CBT may benefit from NAC augmentation.
Impact of socioeconomic disparities on major lower extremity revascularization complications
Authors: McElroy Imani E , Pillado Eric B , Greene Adrienne J , Majumdar Monica , Kirshkaln Amanda , Nuzzolo Kate , Malek Junaid , Dua Anahita 
Published: November 2022

Introduction Low socioeconomic status (SES), distance lived from hospital, and insurance status are well documented in the literature to increase the risk of post-operative morbidity and mortality for some disease processes however there is a paucity of data regarding how this association impacts patients with peripheral artery disease (PAD). This study aimed to evaluate if SES, distance lived from hospital, and insurance status increased the risk of developing major graft failure in patients undergoing revascularization procedures for symptomatic PAD in a prospective, observation study. Methods In this prospective, observational study, all patients undergoing lower extremity revascularization (endovascular or open) were included from December 2020 to February 2022. Demographic factors, insurance status, operative details, and median income and distance from hospital were documented through chart review. Complications were defined as thrombosis/occlusion of the revascularized vessel or bypass graft or infection of the distal wound or surgical incision wound. Univariate and multivariate analysis were performed comparing patients that developed complications and those that did not. This project was undertaken at the Massachusetts General Hospital and was governed by the Institutional Review Board (IRB: 2020P000263) all patients agreed to participation via informed written consent prior to enrollment in the study. Results A total of 108 patients were enrolled in the study of which 94 underwent successful revascularization procedures. Of those 94 patients, 38 (40.4%) underwent open bypass, 39 (41.5%) underwent endovascular revascularization, and 17 (18.1%) underwent a hybrid approach. There were no significant differences in post-operative outcomes between operative approaches. Twenty-five patients (28.7%) experienced major revascularization complications as defined as re-occlusion of the treated vessel/thrombosis of the bypass graft ( n = 13) or development of post-operative infection ( n = 12). There was no significant difference in median income ($75,295 vs $87,757, p = NS), distance lived from hospital, (27.4 miles vs. 29.7 miles, p = NS), or type of insurance (private 24% vs 26%, government 76% vs 73%, p = NS between patients that experienced complications versus those that did not have complications. These findings suggest the risk of major graft failure is independent of a patient’s socioeconomic status, distance lived from hospital, or insurance type in patients undergoing revascularization procedures for PAD. Conclusion While socioeconomic factors impact access to and have a known association with negative outcomes, complications in patients with PAD appear to be independent of these factors. To mitigate the negative outcomes in patients with peripheral artery disease, a focus should be on patient risk factors and modifiable medical factors that contribute to adverse outcomes.
Physiological and clinical impact in the carotid baroreceptor function following the surgical management of bilateral carotid body tumors
Authors: Mier y Teran-Ellis Santiago , Estrada-Rodriguez Humberto A , Anaya-Ayala Javier E , Lopez-Pena Gabriel , Contreras-Jimenez Emmanuel , Dominguez-Vega Rosa X , Gonzalez-Duarte Alejandra , Hinojosa Carlos A 
Published: November 2022

Objective The bilateral presentation of Carotid Body Tumors (CBT) is rare; the surgical resection of these masses remains the mainstay management due to the malignant potential. We aim to describe, classify, and quantify baroreceptor failure (BRF) after the surgical management of patients with bilateral CBT to better understand the clinical consequences. Methods Retrospective review of patients that underwent bilateral CBT resection to assess the changes in baroreceptor function. We describe the clinical events associated to BRF after surgery, baseline patient’s demographics, characteristics, comorbidities. Additionally, clinical and a quantitative evaluation of baroreceptor sensitivity were conducted using the Composite Autonomic Severity Score (CASS). Results From 1986 to 2020, a total 146 CBT resections were performed in 132 patients in our institution. Tumors were removed bilaterally in staged procedures in seven patients with a mean age of 61 years (Standard Deviation 11), six (85%) were females, and there was no family history of paragangliomas. The clinical presentation were palpable masses in 5 (71%), and odynophagia in 2 (29%) cases; malignant histopathology following surgery was found in one case. BRF occurred in one patient after unilateral CBT resection, consisting of bradycardia and a 40 s asystole that was not previously associated to BR sensitivity. Three (43%) patients presented BRF in the immediate postoperative period of the contralateral CBT excision, consisting of volatile hypertensive crisis in two cases, and supraventricular tachycardia in one. All the patients developed (100%) chronic baroreceptor sensitivity symptoms consisting in syncope, vertigo and fatigue in 4 (57%), tachycardia in 2 (28%), and orthostatic headache in one (14%). Autonomic testing showed mixed sympathetic and parasympathetic failure in five (71%), severe sympathetic failure in 1 (14%), and parasympathetic dysfunction in one patient (14%). Conclusions Postoperative autonomic assessment confirmed BRF in all studied patients that underwent staged bilateral CBT resection with mixed, sympathetic, and parasympathetic dysfunction. Further studies are necessary to evaluate the incidence and physiological mechanisms of these sequelae to anticipate possible complications and offer the appropriate perioperative management.
Open versus endovascular repair of primary infected thoracic and abdominal aortic aneurysms
Authors: Kritayakirana Kritaya , Narueponjirakul Natawat , Aimsupanimitr Punthita , Chaichote Chonlathorn , Uthaipaisanwong Apinan , Kittayarak Chanapong 
Published: November 2022

Objective Primary infected aortic aneurysms are life-threatening if not treated promptly, but still possess a high mortality rate following open repair. The goal of treatment is to prevent rupture and clear infection. An endovascular approach is accepted as a bridge to definitive open repair. Our study compares the outcomes of endovascular versus conventional open repair of infected aortic aneurysms. Method A single-center retrospective review was conducted of data from January 2012 to December 2021. Patients were categorized into three cohorts according to aortic involvement: thoracic aortic aneurysm (TAA), thoracoabdominal aortic aneurysm (TAAA), and abdominal aortic aneurysm (AAA). The primary endpoint was survival rate and the assessment of any associated factors. Result Ninety‐nine patients presented with infected aortic aneurysms. Of the 56 patients who presented with infected TAA, 38 patients underwent thoracic endovascular aortic repair and 18 patients underwent open TAA repair. Forty patients presented with infected AAA, of which 21 patients underwent endovascular aortic repair and 19 patients underwent open repair. Three patients presented with infected TAAA and all underwent open repair. The mean age was 67 years (range 33–88); 74 patients (74.8%) were men and 71 patients (71.7%) had immune dysfunction. Mean follow-up time was 24 months in the endovascular repair group and 38 months in the open repair group. The probability survival rate in the endovascular repair group was 86%, 86%, 77% and 51% at 1 year, 2 years, 5 years and 10 years, respectively, and in the open repair group this was 81%, 81%, 76%, and 64% at 1 year, 2 years, 5 years and 10 years, respectively. Conclutions Endovascular repair for primary infected aortic aneurysms plays an important role in current practice as an alternate to open surgery or used as bridging to definitive open surgical repair. No significant difference was observed in either short- or long-term survival in patients with infected aortic aneurysm undergoing open or endovascular repairs.
Embolic protection devices for carotid artery stenting: A network meta-analysis
Authors: Giannopoulos Stefanos , Sagris Marios , Giannopoulos Spyridon , Tzoumas Andreas , Kokkinidis Damianos G , Texakalidis Pavlos , Koutsias George , Volteas Panagiotis , Jing Li , Malgor Rafael D 
Published: November 2022

Objectives Carotid artery stenting (CAS) is an alternative treatment option for patients at high risk for carotid endarterectomy (CEA) but has been correlated with increased risk for distal embolization and periprocedural stroke despite the use of adjunctive embolic protection devices (EPD). This study compared four types of EPDs and their intra and periprocedural related complications. Methods A systematic review of the literature was conducted in PubMed/Medline to identify studies that investigated the outcomes of CAS with adjuvant use of EPDs, including Proximal Balloon (PB), Distal Filter (DF), and Distal Balloon (DB) strategy. Continuous flow reversal performed via transcarotid approach by a commercially available device as an embolic protection strategy was intentionally excluded based on its distinct procedural characteristics and lack of availability outside of the United States. This network meta-analysis was performed according to the PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) guidelines. Results Overall, 45 studies, consisting of 7600 participants satisfied the predetermined search criteria and were included in this network meta-analysis. Overall, 13 studies provided data regarding the number of patients with new ischemic lesions detected in the DW-MRI. DF (OR: 3.15; 95% CI: 1.54–6.44; p = 0.002) and DB (OR: 2.28; 95% CI: 1.58–3.29; p < 0.001) were associated with higher odds of new ischemic lesions compared to PB on DW-MRI imaging. No statistical difference was identified between DB versus DF groups (OR: 1.48; 95% CI: 0.73–2.59; p = 0.317). 36 and 27 studies reported on periprocedural stroke and transient ischemic attack (TIA) rates, respectively, showing similar odds of neurologic adverse events between all three groups. Conclusions PB deployment during CAS is superior to DF and DB in preventing distal embolization phenomena. However, no statistically significant difference in TIA and stroke rate was found among any of the analyzed EPD groups. Further research is warranted to investigate the association of embolic phenomena on imaging after CAS with clinically significant neurologic deficits.
In-Hospital Symptoms of Depression and Anxiety are Strong Risk Factors for Post-Stroke Depression 90 Days After Ischemic Stroke
Authors: Elias Stefany , Benevides Maria Luiza , Pereira Martins André Luiz , Martins Gladys Lentz , Sperb Wanderley Marcos Ana Beatriz , Nunes Jean Costa 
Published: November 2022

Background and Purpose Acute ischemic stroke (AIS) and depression are the major causes of disability and decreased quality of life worldwide. Psychiatric disorders are common after stroke, especially post-stroke depression (PSD), which affects one-third of survivors. Although frequent, little is known about the real complexity of the pathophysiology and the factors associated with PSD. Methods This research aimed to provide data about risk factors and predictors of PSD 90 days after AIS. A cohort study was conducted in a tertiary stroke center located in southern Brazil. We interviewed 148 patients with AIS who were consecutively hospitalized between January 2020 and January 2021. The Hospital Anxiety and Depression Scale (HADS) was applied during hospitalization and at follow-up 90 days after AIS. Furthermore, sociodemographic, clinical, and radiological variables were investigated. Predictive factors were assessed using univariate and multivariate linear regression. The impact of the COVID-19 pandemic on the data was also evaluated. Results The frequency of PSD 90 days after AIS was 33.9%. In-hospital symptoms of depression and anxiety each represented a 2-fold risk for PSD at follow-up. Furthermore, the HADS – anxiety score 90 days after AIS was strongly associated with the HADS – depression value 90 days after stroke (R: .71; B: .56; P < .01). Conclusions The present study highlighted a noteworthy frequency of PSD 90 days after AIS. Psychiatric variables during hospitalization and in the follow-up appeared to be the leading associated factors with PSD. These data might support the determination of which patients require more psychiatric management.
Fatty syringomyelia mimicking lipoma with spinal cord pilocytic astrocytoma
Authors: Arjipour Mahdi , Ownagh Farid , Eftekharian Mohamadmehdi 
Published: November 2022

The reporting case is a 27 year-old woman. She was admitted with complaints of clumsy gait and dysesthesia over her upper limbs and spasticity in the legs. The investigations revealed a long segment cervical intramedullary tumor, associated with whole cord syringomyelia. The superior part of syringomyelia image intensity matched intramedullary lipoma completely. C1–C5 intramedullary tumor was resected grossly under microscopic view, and a fat-containing liquid exited the syringomyelia cavity at its superior pole. After a transient paresis just following the surgery, neurological condition was improved. The follow-up imaging showed that the fatty syringomyelia reduced in dimensions. Conclusion. According to this case and another similar case due to instability, it appears that as a rare phenomenon, syringomyelia liquid content sometimes could have fatty droplets which could mimic intramedullary lipoma with an unknown mechanism. It seems these fat droplets in syringomyelia would not change its natural history.