bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structural, vibrational, and electronic properties of γ-graphyne, γ-graphyne oxide, and boron nitride doped γ-graphyne: A DFT study
Authors: Ahmed Mohammad Tanvir , Islam Shariful , Ahmed Farid 
Published: December 2022

The interesting characteristics of graphyne structure inspired this research to study the effect of oxygen incorporation and boron nitride doping on γ-graphyne. The structural stability, vibrational, and electronic properties of γ-graphyne, γ-graphyne oxide, and boron nitride doped γ-graphyne have been studied via density functional theory. The negative formation energy verified the structural stability of all the structures. Both γ-graphyne oxide and boron nitride doped γ-graphyne showed a significantly deformed geometry compared to pure γ-graphyne. The energy gap of pure γ-graphyne was obtained to be 2.604 eV, which tuned to 3.059 eV and 3.51 eV through oxygen addition and boron nitride doping, respectively. Boron nitride doped γ-graphyne revealed better structural stability, whereas high reactivity was observed for pure γ-graphyne.
The idiosyncratic prepositionzaiin Mandarin Chinese and differential argument marking
Authors: Kuo Pei-Jung 
Published: December 2022

AbstractIn this paper, I focus on the Mandarin spatial prepositionzai(‘at’), which can appear in the VP domain, like other spatial prepositions, but which can also appear in the TP domain, where it’s presence or absence is sensitive to the animacy and definiteness properties of its object. I argue thatzai’sdistribution and behavior in the TP domain is expected if it functions as a differential argument marker triggered by internal topicalization of its object. Implications of the current analysis for the internal structure of spatial PPs are also considered.
The quantity adjectiveduōin Chinese and the event quantity construction
Authors: Liu Chen-Sheng Luther 
Published: December 2022

AbstractIn theduōevent quantity construction,duō‘much’ is a quantity adjective. Whatduō‘much’ modifies is the root of the verb and the root has to move to the light verb position to be categorically defined. The quantity adjectiveduō‘much’ functions to introduce a measure function which measures the event denoted by the verb along the dimension valued by the assignment functionA, and the domain to which the measure function applies must be monotonic. So, the ‘modification’ relation between the quantity adjectiveduō‘much’ and its modifyee essentially differs from that between a typical gradable adjective liketián‘sweat’ and its modifyee. This explains how the quantity adjectiveduō‘much’ differs from the typical adjective in syntax and semantics.
Effect of the laser beam geometry on laser-assisted muon pair production process at

e+e−

collider
Authors: Ouali M , Ouhammou M , Taj S , Manaut B , Benbrik R , Hrour E , El Idrissi M 
Published: December 2022

Abstract
In this research paper, we have investigated the process of muon pair production in high energy

e

+

e

−

collisions via the exchange of γ and Z-bosons in the presence of the laser field for different directions. Analytical calculations of the cross-section are done within the scattering matrix approach by using the Dirac-Volkov states for electron and positron. The numerical computation of the cross-section shows that it behaves differently by changing the laser wave direction. For a laser field propagating in parallel with the incident beam, the cross-section is strongly affected from low intensities. In addition, for a given laser field strength and frequency, the required number of photons to be transferred increases by increasing the centre of mass energy. Therefore, the acceleration gradient provided by a collinear laser field further enhances the centre of mass energy.
A congestion-aware and fault-tolerant readout network ASIC for a high-density electrode array targeting at neutrinoless double-beta decay search in a TPC
Authors: You B. , Xiao L. , Dai W. , Sun X. , Mei Y. , Huang G. 
Published: December 2022

Abstract
We present a distributed, self-organizing, fault-tolerant and congestion-aware readout network application specific integrated circuit (ASIC) for a high-density electrode array targeting at neutrinoless double-beta decay search in a time projection chamber (TPC). A sensor network is proposed to achieve the readout of the high-density electrode array. This network consists of approximately 1 × 105 single-electrode Topmetal-S sensors with a pitch of approximately 5~10 mm. Static routing is implemented in the first version of the sensor network, without the feature of congestion awareness, which means that only one deterministic path is available for a given packet. Because of the limited memory in each sensor, data will be lost when congestion occurs in this first version of the network. Therefore, the network should have congestion awareness to improve its memory occupancy and effective throughput. Accordingly, a 224 × 224 network with congestion awareness is emulated. The simulation results show that better performance of the sensor network can be achieved with less hardware. An ASIC named adaptive and fault-tolerant readout network chip (AFT-RNC) is implemented with 48.2% of the area of the first implementation.
Characterisation of gamma-irradiated MCz-silicon detectors with a high-K negative oxide as field insulator
Authors: Bharthuar S. , Bezak M. , Brücken E. , Gädda A. , Golovleva M. , Karadzhinova-Ferrer A. , Karjalainen A. , Kramarenko N. , Kirschenmann S. , Luukka P. , Ott J. , Tuominen E. , Väänänen M. 
Published: December 2022

Abstract
The high-luminosity operation of the Tracker in the Compact Muon Solenid (CMS) detector at the Large Hadron Collider (LHC) experiment calls for the development of silicon-based sensors. This involves implementation of AC-coupling to micro-scale pixel sensor areas to provide enhanced isolation of radiation-induced leakage currents. The motivation of this study is the development of AC-pixel sensors with negative oxides (such as aluminium oxide — Al2O3 and hafnium oxide — HfO2) as field insulators that possess good dielectric strength and provide radiation hardness. Thin films of Al2O3 and HfO2 grown by atomic layer deposition (ALD) method were used as dielectrics for capacitive coupling. A comparison study based on dielectric material used in MOS capacitors indicate HfO2 as a better candidate since it provides higher sensitivity (where, the term sensitivity is defined as the ratio of the change in flat-band voltage to dose) to negative charge accumulation with gamma irradiation. Further, space charge sign inversion was observed for sensors processed on high resistivity p-type Magnetic Czochralski silicon (MCz-Si) substrates that were irradiated with gamma rays up to a dose of 1 MGy. The inter-pixel resistance values of heavily gamma irradiated AC-coupled pixel sensors suggest that high-K negative oxides as field insulators provide a good electrical isolation between the pixels.
Detection of MeV electrons using a charge integrating hybrid pixel detector
Authors: Fröjdh E. , Baruffaldi F. , Bergamaschi A. , Carulla M. , Dinapoli R. , Greiffenberg D. , Heymes J. , Hinger V. , Ischebeck R. , Mathisen S. , McKenzie J. , Mezza D. , Moustakas K. , Mozzanica A. , Schmitt B. , Zhang J. 
Published: December 2022

Abstract
Electrons are emerging as a strong complement to X-rays for diffraction based studies. In this paper we investigate the performance of a JUNGFRAU detector with 320 um thick silicon sensor at a pulsed electron source. Originally developed for X-ray detection at free electron lasers, JUNGFRAU features a dynamic range of 120 MeV/pixel (implemented with in-pixel gain switching) which translated to about 1200 incident electrons per pixel and frame in the MeV region. We preset basic characteristics such as energy deposited per incident particle, resulting cluster size and spatial resolution along with dynamic (intensity) range scans. Measurements were performed at 4, 10 and 20 MeV/c. We compare the measurements with GEANT4 based simulations and extrapolate the results to different sensor thicknesses using these simulations.
Investigating the effect of depth of interaction on coincidence time resolution
Authors: Ko K. , Choi H. , Kim W. , Yi Y. , Cho G. 
Published: December 2022

Abstract
The timing properties of scintillator-based detectors are a matter of importance in a wide range of fields. As fast scintillators progress and the sensors that preserve the quantized nature of the luminescent signal evolve, the optical transfer time may not always be negligible in ultra-fast time measurement. The present paper discusses the implications of this in a specific configuration for ultra-fast time measurement. To this end, we consider factors influencing the time spread such as the distribution of depth of interaction, non-instantaneous scintillation emission mechanism, and optical transport kinetics. Although such a topic has previously been studied by researchers, the aim of this work is focused on analyzing the detailed factors that govern arrival time spread. From these factors, we are able to obtain the post-interaction time spread, and we then derived the optical transfer time spread (OTTS) by a weighted sum of post-interaction time spread based on the cumulative density function of the depth of interaction. Based on the rejection sampling method, we could obtain the set of arrival times by the OTTS, and then the coincidence time resolution of radioactive sources was calculated. Consequently, we found that the difference in the attenuation coefficient causes the difference in the arrival time distribution, but it does not lend a significant contribution to the coincidence time resolution. In addition, when radiation with different energies is incident, the emission mechanism has a dominant effect on the time resolution, and thus incident radiation having higher energy in the same detector system has a higher light yield, which can exhibit better timing resolution compared to radiation with relatively low energy.
Study of timing performance parameters for a SiPM-based digital positron annihilation lifetime spectrometer
Authors: Choi H. , Ko K. , Kim W. , Lee J. , Sun G. , Chang H. , Yi Y. , Cho G. 
Published: December 2022

Abstract
Positron annihilation lifetime spectroscopy (PALS) is a popular method for studying defects in materials. With the development of fast digital oscilloscopes and digitizers, the conventional analog positron annihilation lifetime (PAL) spectrometer is being replaced by a digital PAL spectrometer. Recently, newly conducted research has developed a PAL spectrometer using a silicon photomultiplier (SiPM) instead of a photomultiplier tube (PMT). Timing resolution of PAL spectrometer needs to be improved to identify the lifetimes of positrons. Many parameters affect the timing performance of a SiPM-based digital PAL spectrometer: bias voltage, pulse smoothing, and the constant fraction value of digital constant fraction discrimination (dCFD). Timing resolution depends on the radiation energy, but only a few studies have considered the energy difference of 1274 keV and 511 keV. In this study, we optimized the timing performance parameters of the SiPM-based digital PAL spectrometer by conducting the timing resolution measurements using two γ-ray sources (22Na and 60Co). With a 32 V bias voltage, 5th degree polynomial fitting method, and optimal constant fraction value, we optimized the timing resolution of our SiPM-based digital PAL spectrometer. Furthermore, the optimal constant fraction value depended on the γ-ray energy and we verified it by timing resolution measurement using 207Bi. We studied the reason why performance parameters have optimal conditions and the optimal constant fraction value varies depending on the γ-ray energy. With optimized performance parameters, we measured the lifetime spectrum of pure silicon to confirm the SiPM-based digital PAL spectrometer. The timing resolution function of the SiPM-based digital PAL spectrometer was 185.6 ps.
High-precision thermostat for light scattering experiments of critical samples
Authors: Naseer A.P. , Santhi Krishna U. , Madhavan Unni P.K. 
Published: December 2022

Abstract
The characteristics of PID controllers lead to their widespread adoption and strong demand in temperature control systems since the experimental stability of temperature is required for many applied and research endeavours. The design and manufacture of both the thermal and electronic components of the milli-kelvin metallic thermostat, as well as the light scattering experimental set-up for the liquid mixture critical point research, are presented in this publication. The thermostat was tuned over a wide temperature range of 30–106°C, and short-term stability, long-term stability, and transient responses were studied in detail. The findings demonstrate that the thermostat provides accurate and steady temperature stability. The light scattering experimental setup was arranged and a LabVIEW software program was developed for data acquisition of the intensity of the incident beam, scattered beam, transmitted beam, and the temperature of the liquid mixture simultaneously.
Short time sequential luminescence imaging of water during irradiation by protons
Authors: Yamamoto Seiichi , Yabe Takuya , Yogo Katsunori , Akagi Takashi , Kataoka Jun 
Published: December 2022

Abstract
Although luminescence imaging of water during irradiation by particle ions is a promising method for dose estimation, it has only been tried for static images in which temporal information is not included. In addition to the positional distribution of the beam, temporal information is also important because the beams from a synchrotron-based therapy system have short pulse shapes called spills. The temporal information is also important for high dose rate, short-time radiotherapy, or so-called FLASH radiotherapy. To measure the particle ion beam distributions with precise temporal information, we conducted short time sequential luminescence imaging of protons. First, we measured short time sequential luminescence images during irradiation of a water phantom by 150-MeV protons using a cooled charge-coupled device (CCD) camera at 0.143-s intervals. With this imaging, the images showed beam distributions, but the shapes of the spill were not precisely evaluated in time intensity curves due to the insufficient sampling rate of the imaging. Then we measured short time sequential optical images with 0.053-s intervals. With this imaging, the images showed that the beam distributions in the spill shape could be measured, but the image and depth profiles evaluated from the images were noisy due to the insufficient light intensity. Consequently, we measured short time sequential luminescence images during irradiation of fluorescein (FS) water by 150-MeV protons. Since FS water produced ∼10 times higher luminescence, we could obtain high-intensity images enabling us to evaluate the time intensity curves based on the shape of the spills during measurement with 0.053-s intervals. The depth profiles of the beam were also obtained from the measured images. With these results, we confirmed that time sequential luminescence imaging was possible and, in such cases, FS water images measured at 0.053-s intervals are most promising to measure the short time sequential luminescence images during irradiation of protons.
Autorrelation and cross-relation of graphs and networks
Authors: da Fontoura Costa Luciano 
Published: December 2022

Abstract
The concepts of auto- and cross-correlation play a key role in several areas, including signal processing and analysis, pattern recognition, multivariate statistics, as well as physics in general, as these operations underlie several real-world structures and dynamics. In the present work, the concept of multiset similarity, more specifically the coincidence similarity index, is used as the basis for defining operations between a same network, or two distinct networks, which will be respectively called autorrelation and cross-relation. In analogous manner to the autocorrelation and cross-correlation counterparts, which are defined in terms of inner products between signals, the two operations suggested here allow the comparison of the similarity of nodes and graphs respectively to successive displacements along the neighborhoods of each of the constituent nodes, which therefore plays a role that is analogue to the lag in the class correlation. In addition to presenting these approaches, this work also illustrates their potential respectively to applications for the characterization of several model-theoretic and real world networks, providing a comprehensive description of the specific properties of each analyzed structure. The possibility of analyzing the obtained individual autorrelation signatures in terms of their respective coincidence similarity networks is also addressed and illustrated.
The Efficacy of Different Nerve Blocks on Postoperative Pain and Sequelae in Patients Undergoing Abdominoplasty: A Network Meta-Analysis
Authors: Seretis Konstantinos , Bounas Nikolaos 
Published: December 2022

AbstractBackgroundAlthough abdominoplasty is growing in popularity, it still results in considerable postoperative pain, which prolongs recovery.ObjectivesThe aim of this network meta-analysis was to combine evidence about different regional nerve blocks to examine their effectiveness in the management of postoperative pain sequelae and recovery following abdominoplasty.MethodsAn electronic literature search in the MEDLINE (PubMed; National Institutes of Health, Bethesda, MD), Scopus (Elsevier, Amsterdam, the Netherlands), Cochrane Library (London, UK) and US National Institutes of Health Ongoing Trials Register electronic databases (Bethesda, MD) was conducted from inception to July 2022. Inclusion criteria were the presence of intervention and control groups; data derived from controlled studies evaluating nerve blocks after abdominoplasty, in terms of analgesia needs, complications, and patient satisfaction; and publication in peer-reviewed journals. The quality of studies was assessed via Cochrane's risk-of-bias tool. A frequentist random-effects network meta-analysis was conducted for all outcomes of interest.ResultsA total of 12 studies, containing 543 patients with no differences in age, sex, BMI, and comorbidities, met the inclusion criteria. Transversus abdominis plane blocks have been found to reduce 24-hour and 48-hour opioid consumption (−3.70 and −5.01 weighted mean difference, respectively). In addition, the nerve blocks reviewed effectively prolonged the time to first rescue analgesia request, were safe in terms of complications, and were associated with high satisfaction rates.ConclusionsNerve blocks emerge as an effective and safe adjunct for adequate pain management following abdominoplasty. This meta-analysis provides an evidence-based strategy to optimize the current analgesia regimens following abdominoplasty.Level of Evidence: 3
Pdif-mediated antibiotic resistance genes transfer in bacteria identified by pdifFinder
Authors: Shao Mengjie , Ying Nanjiao , Liang Qian , Ma Nan , Leptihn Sebastian , Yu Yunsong , Chen Huan , Liu Chengzhi , Hua Xiaoting 
Published: December 2022

Abstract
Modules consisting of antibiotic resistance genes (ARGs) flanked by inverted repeat Xer-specific recombination sites were thought to be mobile genetic elements that promote horizontal transmission. Less frequently, the presence of mobile modules in plasmids, which facilitate a pdif-mediated ARGs transfer, has been reported. Here, numerous ARGs and toxin-antitoxin genes have been found in pdif site pairs. However, the mechanisms underlying this apparent genetic mobility is currently not understood, and the studies relating to pdif-mediated ARGs transfer onto most bacterial genera are lacking. We developed the web server pdifFinder based on an algorithm called PdifSM that allows the prediction of diverse pdif-ARGs modules in bacterial genomes. Using test set consisting of almost 32 thousand plasmids from 717 species, PdifSM identified 481 plasmids from various bacteria containing pdif sites with ARGs. We found 28-bp-long elements from different genera with clear base preferences. The data we obtained indicate that XerCD-dif site-specific recombination mechanism may have evolutionary adapted to facilitate the pdif-mediated ARGs transfer. Through multiple sequence alignment and evolutionary analyses of duplicated pdif-ARGs modules, we discovered that pdif sites allow an interspecies transfer of ARGs but also across different genera. Mutations in pdif sites generate diverse arrays of modules which mediate multidrug-resistance, as these contain variable numbers of diverse ARGs, insertion sequences and other functional genes. The identification of pdif-ARGs modules and studies focused on the mechanism of ARGs co-transfer will help us to understand and possibly allow controlling the spread of MDR bacteria in clinical settings. The pdifFinder code, standalone software package and description with tutorials are available at https://github.com/mjshao06/pdifFinder.
A recombinant Der p 1-specific allergen-toxin demonstrates superior killing of allergen-reactive IgG+ hybridomas in comparison to its recombinant allergen-drug conjugate
Authors: Daramola A K , Akinrinmade O A , Fajemisin E A , Naran K , Mthembu N , Hadebe S , Brombacher F , Huysamen A M , Fadeyi O E , Hunter R , Barth S 
Published: December 2022

SummaryIntroductionCurrent treatments for asthma help to alleviate clinical symptoms but do not cure the disease. In this study, we explored a novel therapeutic approach for the treatment of house dust mite allergen Der p 1induced asthma by aiming to eliminate specific population of B-cells involved in memory IgE response to Der p 1.Materials and MethodsTo achieve this aim, we developed and evaluated two different proDer p 1-based fusion proteins; an allergen-toxin (proDer p 1-ETA) and an allergen-drug conjugate (ADC) (proDer p 1-SNAP-AURIF) against Der p 1 reactive hybridomas as an in vitro model for Der p 1 reactive human B-cells. The strategy involved the use of proDer p 1 allergen as a cell-specific ligand to selectively deliver the bacterial protein toxin Pseudomonas exotoxin A (ETA) or the synthetic small molecule toxin Auristatin F (AURIF) into the cytosol of Der p 1 reactive cells for highly efficient cell killing.ResultsAs such, we demonstrated recombinant proDer p 1 fusion proteins were selectively bound by Der p 1 reactive hybridomas as well as primary IgG1+ B-cells from HDM-sensitized mice. The therapeutic potential of proDer p 1-ETAʹ and proDer p 1-SNAP-AURIF was confirmed by their selective cytotoxic activities on Der p 1 reactive hybridoma cells. The allergen-toxin demonstrated superior cytotoxic activity, with IC50 values in the single digit nanomolar value, compared to the ADC.DiscussionsAltogether, the proof-of-concept experiments in this study provide a promising approach for the treatment of patients with house dust mite-driven allergic asthma.