bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimal administration time of vitamin C after 131I therapy in differentiated thyroid cancer based on propensity score matching
Authors: Liu Ye , Wang Yuhua , Zhang Wanchun 
Published: September 2022

ObjectivesThis study aimed to investigate the protection of the salivary glands by vitamin C administration at 2 and 24 h after an initial treatment using iodine-131 (131I) in patients with differentiated thyroid cancer (DTC) and examined the optimal administration time of vitamin C to protect the salivary glands from radiation injury.MethodThe clinical data of patients with differentiated thyroid carcinoma who had been treated with 131I in the Department of Nuclear Medicine in Shanxi Bethune Hospital from January 2014 to December 2020 were retrospectively analyzed. The propensity score matching method was adopted to match patients who received the administration of vitamin C at 2 h with those receiving administration at 24 h. A total of 230 pairs/460 patients were enrolled in the study. The chi-squared (χ2) or Fisher's exact test was used to compare the indicators representing the incidence of salivary gland injury between the two groups.ResultsThe incidence of salivary gland injury (17.39%) with acidic substances at 2 h was lower compared with administration at 24 h (26.96%). The incidence of acute salivary gland injury (15.22%) and chronic salivary gland injury (26.09%) in the 24-h group were higher than those in the 2-h group (4.78% and 18.26%, respectively). The differences in the left submandibular gland concentrate index and right submandibular gland concentrate index were statistically significant before and after treatment in both the 2 and the 24-h groups; these functions had been impaired after treatment.ConclusionsFollowing treatment with 131I, the protective effect of acidic substances administered at 2 and 24 h on the salivary glands were different. The incidence of salivary gland injury in the 2 h acid stimulation group was lower than in the 24 h acid stimulation group. The present study revealed that 131I treatment did cause some injury to the salivary glands and that the protective effect of administering vitamin C at 2 and 24 h may be limited. Accordingly, protection against salivary gland injury should be conducted using comprehensive measures.
La problemática social y ecológica en la microcuenca del Cupatitzio-Márquez
Authors: Sánchez Andrade Diana Elizabeth , Sandoval Contreras Rigoberto 
Published: September 2022

En este trabajo se resumen los resultados de una investigación realizada sobre la problemática de la microcuenca del Cupatitzio-Marqués ubicada en el estado de Michoacán. El tema trata de cómo a partir del uso intensivo y diversificadoque se le ha dado al agua del río Cupatitzio-Marqués, desde mediados del siglo XIX y hasta em momento actual, hacontribuido a la transformación de los paisajes, al deterioro medioambiental y al proceso de formación de relaciones depoder de los diferentes grupos socioculturales presentes en las tres zonas bioclimáticas de una unidad ecológica vertebrada poresta corriente de agua.
PENGARUH PENGALAMAN KERJA, KOMPETENSI DAN MOTIVASI KERJA TERHADAP KINERJA APARATUR SIPIL NEGruh Pengalaman Kerja, Kompetensi dan Motivasi Kerja terhadap Kinerja Aparatur Sipil Negara pada Kantor Kecamatan Maritengngae Kabupaten Sidenreng Rappang
Authors: Eni Nur'eni.A , Razak Mashur , Dandu Sudirman 
Published: September 2022

Penelitian ini bertujuan untuk mengetahui dan menganalisis (1) pengaruh pengalaman kerja, kompetensi dan motivasi kerja secara parsial dan simultan terhadap kinerja Aparatur Sipil Negara pada Kantor Kecamatan Maritengngae Kabupaten Sidenreng Rappang (2) variabel yang paling dominan berpengaruh terhadap kinerja Aparatur Sipil Negara pada Kantor Kecamatan Maritengngae Kabupaten Sidenreng Rappang.
Metode pengumpulan data yang digunakan adalah angket dan studi dokumen. Metode analisis yang digunakan adalah analisis statistik deskriptif dan analisis regresi linear berganda.
Hasil penelitian menunjukkan bahwa (1) secara parsial pengalaman kerja, kompetensi, dan motivasi berpengaruh positif dan signifikan terhadap kinerja
Aparatur Sipil Negara pada Kantor Kecamatan Maritengngae Kabupaten Sidenreng Rappang (2) secara simultan pengalaman kerja, kompetensi dan motivasi kerja berpengaruh positif dan signifikan terhadap kinerja pegawai Kecamatan Maritengngae Kabupaten Sidenreng Rappang. Hal ini berarti semakin baik
pengalaman kerja, kompetensi dan motivasi kerja yang dimiliki oleh pegawai maka kinerja pegawai akan semakin baik pula (3) variabel kompetensi memiliki pengaruh paling dominan dan signifikan terhadap kinerja pegawai di kecamatan Maritengngae Kabupaten Sidenreng Rappang.
Federalism and the Minorities in Nigeria: A Geopolitical Analysis
Authors:   Professor, University of Delhi, Department of African Studies, Faculty of Social Sciences, Delhi-110007, INDIA, Kumar Suresh , Yadav Smita ,   Assistant Professor, Department of Political Science, Daulat Ram College, University of Delhi, Delhi-110007, INDIA, Gupta Vibha ,   Associate Professor, Department of Commerce, Lakshmibai College, University of Delhi, III-Ashok Vihar, Delhi-110052, INDIA
Published: September 2022

This article examines federalism, its challenges, and minority agitations for equity and development in Nigeria. It explores the geopolitical analysis to have smooth development in Nigeria and seeks to abort all or any discrimination against the minorities section of the society. This paper further suggests the methods of enhanced protection of minorities’ rights and the practice of true federalism in Nigeria. Nigerian Governments have tried to practice federalism to promote equity and minorities’ rights, but they have failed to adhere to this doctrine as stipulated in the constitution, thereby raising the question of minority marginalization in Nigeria. This article assesses that unless the Government practices federalism as enshrined in the constitution and generates resource control, power sharing, equal rights, and accountability, it may become a permanent source of geopolitical conflicts in the coming days.
Pressure-regulated, Feedback-modulated Star Formation in Disk Galaxies
Authors: Ostriker Eve C. , Kim Chang-Goo 
Published: September 2022

Abstract
The star formation rate (SFR) in galactic disks depends on both the quantity of the available interstellar medium (ISM) gas and its physical state. Conversely, the ISM’s physical state depends on the SFR, because the “feedback” energy and momentum injected by recently formed massive stars is crucial to offsetting losses from turbulent dissipation and radiative cooling. The ISM’s physical state also responds to the gravitational field that confines it, with increased weight driving higher pressure. In a quasi-steady state, it is expected that the mean total pressure of different thermal phases will match each other, that the component pressures and total pressure will satisfy thermal and dynamical equilibrium requirements, and that the SFR will adjust as needed to provide the requisite stellar radiation and supernova feedback. The pressure-regulated, feedback-modulated (PRFM) theory of the star-forming ISM formalizes these ideas, leading to a prediction that the SFR per unit area, ΣSFR, will scale nearly linearly with ISM weight



. In terms of the large-scale gas surface density Σgas, stellar plus dark matter density ρ
sd, and effective ISM velocity dispersion σ
eff, an observable weight estimator is


≈

P

DE

=
π
G

Σ

gas

2

/

2
+

Σ

gas

(
2
G

ρ

sd

)

1

/

2

σ

eff

, and this is predicted to match the total midplane pressure P
tot. Using a suite of multiphase magnetohydrodynamic simulations run with the TIGRESS computational framework, we test the principles of the PRFM model and calibrate the total feedback yield ϒtot = P
tot/ΣSFR ∼ 1000 km s−1, as well as its components. We compare the results from TIGRESS to theory, previous numerical simulations, and observations, finding excellent agreement.
Effects of Spectral Resolution on Simple Magnetic Field Diagnostics of the Mg ii H and K Lines
Authors: Centeno Rebecca , Rempel Matthias , Casini Roberto , del Pino Alemán Tanausú 
Published: September 2022

Abstract
We study the effects of finite spectral resolution on the magnetic field values retrieved through the weak-field approximation (WFA) from the cores of the Mg ii h and k lines. The retrieval of the line-of-sight component of the magnetic field, B
LOS, from synthetic spectra generated in a uniformly magnetized FAL-C atmosphere is accurate when restricted to the inner lobes of Stokes V. As we degrade the spectral resolution, partial redistribution effects, which more prominently affect the outer lobes of Stokes V, are brought into the line core through spectral smearing, degrading the accuracy of the WFA and resulting in an inference bias, which is more pronounced as the resolution becomes poorer. When applied to a diverse set of spectra emerging from a sunspot simulation, we find good accuracy in the retrieved B
LOS when comparing it to the model value at the height where the optical depth in the line core is unity. The accuracy is preserved up to field strengths of B ∼ 1500 G. Limited spectral resolution results in a small bias toward weaker retrieved fields. The WFA for the transverse component of the magnetic field is also evaluated. Reduced spectral resolution degrades the accuracy of the inferences, because spectral mixing results in the line effectively probing deeper layers of the atmosphere.
L’industrie manufacturière allemande pourra-t-elle passer l’hiver ?
Authors: Commun Patricia 
Published: September 2022

L’industrie allemande représente 25 % environ du PIB allemand mais aussi 46 % de la consommation énergétique nationale. Or, elle se trouve confrontée actuellement à un triple défi : raréfaction des énergies fossiles produites sur le sol allemand, retards pris par les énergies renouvelables, fin brutale des importations de gaz et de charbon russes. L’industrie allemande est-elle en mesure de survivre sur le sol allemand ? Quelles actions la coalition tricolore met-elle en œuvre pour sauver le site Allemagne ? Comment l’Allemagne va-t-elle concilier souveraineté énergétique, globalisation et baisse drastique des émissions de CO 2 dans les mois et années à venir ?
Nommer les « nouveaux pauvres »
Authors: Lavabre Alice 
Published: September 2022

Depuis les années 1980, la question de l’insertion professionnelle s’est imposée dans de nombreux organismes d’assistance aux pauvres, dont les associations caritatives. Cet article a pour objet d’interroger la manière dont s’y définit le statut de ces « nouveaux pauvres ». Adoptant une approche institutionnelle de la pauvreté, il montre, à partir d’une double enquête quantitative et qualitative, que l’introduction de la question de l’emploi dans ce monde associatif s’est accompagnée d’une prise de distance avec la figure du « pauvre », sans pour autant conduire à celle du « chômeur », ni même toujours à celle du « précaire ». Les modes de désignation des individus pris en charge y sont divers et peu stabilisés : « éloignés de l’emploi », « personnes fragiles », « très en difficulté », voire simplement « bénéficiaires », « accueillis », « usagers ». Ils révèlent l’indétermination qui caractérise encore aujourd’hui le statut du public de ces structures, plus de trente ans après l’émergence de la problématique de la « nouvelle pauvreté » en France. Cet article a pour but d’éclairer les ressorts de cette indétermination persistante.
PENGENDALIAN ANTIBIOTIK BERDASAR METODE KONSUMSI ABC DENGAN PENERAPAN MINIMUM-MAXIMUM STOCK LEVEL TERHADAP EFISIENSI PERSEDIAAN FARMASI RUMAH SAKIT
Authors: Pranata Yudha , Banun Agusdini , Hilmy Mohamad Reza 
Published: September 2022

Perencanaan dan pengendalian persediaan obat yang tidak efisien selain dapat menyebabkan kekurangan atau kelebihan stok, juga dapat menyebabkan inefisien dalam biaya operasional rumah sakit. Penelitian ini bertujuan untuk mengetahui pengaruh penerapan metode Minimum-Maximum Stock Level (MMSL) pada efisiensi dan efektifitas persediaan obat di Instalasi Farmasi RSU. Sentra Medika Sanggau. Sampel kelompok obat antibiotik golongan A dari metode konsumsi ABC sebanyak 22 jenis obat diambil secara purposive dari data retrospektif bulan Januari - Juni 2021, dan dilakukan penerapan metode MMSL secara prospektif pada bulan Oktober - Desember 2021.
Dilakukan analisa data nilai persediaan, month-stock, serta ITOR (Inventory Turn Over Ratio) sebelum dan sesudah penerapan metode MMSL menggunakan uji statistik Wilcoxon Signed Rank Test.
Hasil uji statistik menunjukkan pengaruh penerapan metode MMSL terhadap rasio month-stock kelompok antibiotik sebelum intervensi sebesar 2,87 dan sesudah intervensi 2,03 dengan nilai p = 0,021 (p<0,05). Sedangkan nilai ITOR sebelum intervensi 13,73 kali/tahun dan sesudah intervensi 19,16 kali/tahun dengan nilai p = 0,006 (p<0,05). Meskipun tidak menunjukkan perbedaan yang bermakna pada nilai persediaan kelompok antibiotik antara sebelum intervensi (Rp. 62.497.441,)- dan sesudah intervensi (Rp. 54.072.358,-), dengan nilai p = 0,236 (p>0,05), namun menunjukkan efisensi sebesar 13,48%.
Penerapan metode MMSL memberikan dampak positif terhadap meningkatnya efisiensi pengendalian obat di Rumah Sakit dengan menurunnya nilai persediaan dan rasio month-stock, serta meningkatkan ITOR.
Zanubrutinib (Brukinsa)
Authors: CADTH  
Published: September 2022

CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.
This review assesses zanubrutinib (Brukinsa) 80 mg capsules; oral.
Indication: For the treatment of adult patients with mantle cell lymphoma who have received at least 1 prior therapy.
A global marine particle size distribution dataset obtained with the Underwater Vision Profiler 5
Authors: Kiko Rainer , Picheral Marc , Antoine David , Babin Marcel , Berline Léo , Biard Tristan , Boss Emmanuel , Brandt Peter , Carlotti Francois , Christiansen Svenja , Coppola Laurent , de la Cruz Leandro , Diamond-Riquier Emilie , Durrieu de Madron Xavier , Elineau Amanda , Gorsky Gabriel , Guidi Lionel , Hauss Helena , Irisson Jean-Olivier , Karp-Boss Lee , Karstensen Johannes , Kim Dong-gyun , Lekanoff Rachel M. , Lombard Fabien , Lopes Rubens M. , Marec Claudie , McDonnell Andrew M. P. , Niemeyer Daniela , Noyon Margaux , O'Daly Stephanie H. , Ohman Mark D. , Pretty Jessica L. , Rogge Andreas , Searson Sarah , Shibata Masashi , Tanaka Yuji , Tanhua Toste , Taucher Jan , Trudnowska Emilia , Turner Jessica S. , Waite Anya , Stemmann Lars 
Published: September 2022

Abstract. Marine particles of different nature are found throughout the global
ocean. The term “marine particles” describes detritus aggregates and
fecal pellets as well as bacterioplankton, phytoplankton, zooplankton and
nekton. Here, we present a global particle size distribution dataset
obtained with several Underwater Vision Profiler 5 (UVP5) camera
systems. Overall, within the 64 µm to about 50 mm size range covered
by the UVP5, detrital particles are the most abundant component of all
marine particles; thus, measurements of the
particle size distribution with the UVP5 can yield important
information on detrital particle dynamics. During deployment, which is
possible down to 6000 m depth, the UVP5 images a volume of about 1 L
at a frequency of 6 to 20 Hz. Each image is segmented in real time, and
size measurements of particles are automatically stored. All UVP5
units used to generate the dataset presented here were
inter-calibrated using a UVP5 high-definition unit as reference. Our
consistent particle size distribution dataset contains 8805 vertical
profiles collected between 19 June 2008 and 23 November 2020. All major ocean basins, as well as the Mediterranean Sea and the Baltic Sea, were sampled. A total of 19 % of all profiles had a maximum sampling depth shallower than 200 dbar, 38 % sampled at least the upper 1000 dbar depth range and 11 % went down to at least 3000 dbar depth. First analysis of the particle size distribution dataset shows that particle abundance is found to be high at high latitudes and in coastal areas where surface productivity or continental inputs are elevated. The lowest values are found in the deep ocean and in the oceanic gyres. Our dataset should be valuable for more in-depth studies that focus on the analysis of regional, temporal and global patterns of particle size distribution and flux as well as for the development and adjustment of regional and global biogeochemical models. The marine particle size distribution dataset (Kiko et al., 2021) is available at https://doi.org/10.1594/PANGAEA.924375.
The biogeography of relative abundance of soil fungi versus bacteria in surface topsoil
Authors: Yu Kailiang , van den Hoogen Johan , Wang Zhiqiang , Averill Colin , Routh Devin , Smith Gabriel Reuben , Drenovsky Rebecca E. , Scow Kate M. , Mo Fei , Waldrop Mark P. , Yang Yuanhe , Tang Weize , De Vries Franciska T. , Bardgett Richard D. , Manning Peter , Bastida Felipe , Baer Sara G. , Bach Elizabeth M. , García Carlos , Wang Qingkui , Ma Linna , Chen Baodong , He Xianjing , Teurlincx Sven , Heijboer Amber , Bradley James A. , Crowther Thomas W. 
Published: September 2022

Abstract. Fungi and bacteria are the two dominant groups of soil microbial
communities worldwide. By controlling the turnover of soil organic matter,
these organisms directly regulate the cycling of carbon between the soil and
the atmosphere. Fundamental differences in the physiology and life history
of bacteria and fungi suggest that variation in the biogeography of relative abundance of soil fungi versus bacteria could drive striking differences in
carbon decomposition and soil organic matter formation between different
biomes. However, a lack of global and predictive information on the
distribution of these organisms in terrestrial ecosystems has prevented the
inclusion of relative abundance of soil fungi versus bacteria and the associated
processes in global biogeochemical models. Here, we used a global-scale
dataset of >3000 distinct observations of abundance of soil fungi versus bacteria in the surface topsoil (up to 15 cm) to generate the
first quantitative and high-spatial-resolution (1 km2) explicit map of
soil fungal proportion, defined as fungi/fungi + bacteria, across
terrestrial ecosystems. We reveal striking latitudinal trends where fungal
dominance increases in cold and high-latitude environments with large soil
carbon stocks. There was a strong nonlinear response of fungal dominance to the
environmental gradient, i.e., mean annual temperature (MAT) and net primary
productivity (NPP). Fungi dominated in regions with low MAT and NPP and bacteria dominated in regions with high MAT and NPP, thus representing slow vs. fast soil energy
channels, respectively, a concept with a long history in soil ecology. These
high-resolution models provide the first steps towards representing the
major soil microbial groups and their functional differences in global
biogeochemical models to improve predictions of soil organic matter turnover
under current and future climate scenarios. Raw datasets and global maps
generated in this study are available at https://doi.org/10.6084/m9.figshare.19556419 (Yu, 2022).
“WHY WE SHOULD ANNEX”: Reprints and Repercussions of Twain’s New York Tribune Letters on Hawai‘i
Authors: Thompson Todd Nathan 
Published: September 2022

Abstract
The December 1872 death of Hawaiian monarch Kamehameha V spurred renewed interest among U.S. citizens and politicians alike in the annexation of the Hawaiian Islands. To satisfy the public’s increased curiosity about Hawai‘i, in January 1873 the New York Tribune sought testimony in the form of two letters from a well-known expert on the islands: Mark Twain, who had gained nationwide fame based his popular comic lecture “Our Fellow Savages of the Sandwich Islands,” which he delivered across the United States and abroad between 1866 and 1873. Between January and March of 1873 at least seventy newspapers and magazines reprinted excerpts of Mark Twain’s Tribune letters. This article considers how these reprinted excerpts decontextualize or mischaracterize Mark Twain’s insights as well as what they reveal about the American reading public’s views of Mark Twain as both a comedian and as a serious expert on Hawai‘i in the early 1870s.
Political Corruption and Mark Twain’s West
Authors: Hebard Andrew 
Published: September 2022

Abstract
This article argues that Mark Twain’s West was a bureaucratically managed space and that his depictions of western institutions reveal forms of political corruption that are not venal. Unlike the corruption that the Supreme Court has recently limited to quid pro quo exchanges of money for political favors by individuals, the corruption that Twain reveals through the lens of his western experiences is endemic to institutions and can often involve well-meaning individuals who are not acting in criminal ways.
Anthro-demographic, clinico-pathological and biochemical risk factors in cervical cancer
Authors: Kushwah Atar Singh , Mishra Rajnikant , Srivastava Kirti , Mishra Shambhavi , Banerjee Monisha 
Published: September 2022

Background: In India, cervical cancer (CaCx) ranks second with >1.2 lakh new cases and >77,000 deaths. The main causing agent of cervical cancer is human papillomavirus (HPV). Recently, anthro-demographic and clinico-pathological factors have been implicative of cancer development and progression. Objective: To evaluate the association of anthro-demographic, clinico-pathological and biochemical risk factors in cervical cancer. Methods: CaCx patients were tested for HPV infection using conventional PCR. Anthro-demographic and clinico-pathological characteristics were recorded and samples from patients (n=103) and healthy women (n=108) were analyzed for lipid profile, serum urea, creatinine and uric acid using commercial kits. Statistical analysis was done using SPSS (ver.21.0) and GraphPad. Results: Out of 103 CaCx patients, 86 were HPV+ve and 17 HPV-ve. Anthro-demographic factors like literacy, socio-economic status and obstetrics were found significantly associated with cervical cancer. BMI was associated with cervical cancer (1.18 folds higher risk). Total cholesterol (TC); triglycerides (TG); high-density lipoprotein (HDL) and low-density lipoprotein (LDL) were found significantly associated with an increased adjusted OR in CaCx patients. Urea levels were found significantly higher in patients (1.11 folds crude OR vs 1.31 adjusted OR). Similarly, creatinine levels were significantly higher in patients (2.64 folds crude OR vs 3.37 adjusted OR).