bluuebunny/crossref_metadata_2025_split huggingface dataset:
Concepts of Heterogeneously Catalyzed Liquid‐Phase Oxidation of Cyclohexene with tert‐Butyl Hydroperoxide, Hydrogen Peroxide and Molecular Oxygen
Authors: Büker Julia , Muhler Martin , Peng Baoxiang 
Published: November 2022

AbstractThe oxidation of hydrocarbons is of great significance for the chemical industry as it provides access to valuable functionalized chemicals. The oxidation of cyclohexene has raised much interest because it enables the direct synthesis of adipic acid, which is an important building block in polymer chemistry. However, the selective oxidation of cyclohexene is rather challenging due to its two reactive centers so that epoxidation or allylic oxidation may occur leading to a variety of products. Whether the oxidation takes place at the allylic C−H bond or at the C=C bond is strongly influenced by the chosen oxidant and catalyst, and different reaction mechanisms can occur. Therefore, this concept article aims at giving a broad overview of the recent advances in the selective cyclohexene oxidation over heterogeneous transition metal‐based catalysts using environmentally benign oxidants like tert‐butyl hydroperoxide, H2O2 and molecular O2.
A Two‐in‐One Annealing Enables Dopant Free Block Copolymer Based Organic Solar Cells with over 16% Efficiency
Authors: Yao Shangfei , Yang Linji , Shi Shasha , Zhou Yang , Long Min , Zhang Wenhao , Cai Songlin , Huang Ciyuan , Liu Tao , Zou Bingsuo 
Published: November 2022

Comprehensive SummaryThe organic solar cells (OSCs) based on block copolymer systems bear the hope of achieving the optimal balance of power conversion efficiency (PCE) and stability, but the key index, PCE of this type devices is still low. To improve the efficiency, regulating the thin‐film morphology is always the core engineering, which is usually achieved via two aspects: precursor optimization and post treatments. Herein, we extend our previous success in post treatments (two step annealing) to a novel two‐in‐one annealing tactic, which realizes limited phase separation and well‐connected domain distribution. As a result, the optimal PCE as high as 16.08%, representing the cutting‐edge level of block copolymer based OSCs (notably dopant free). Furthermore, a comprehensive study on all kinds of annealing methods is carried out, including TA, SVA, SVA+TA, TA+SVA and SVTA (the best one), and an in‐depth understanding is demonstrated, with the help of different characterizations.
Empirical‐process‐based specification tests for diffusion models
Authors: Chen Qiang , Gong Yuting , Wang Xunxiao 
Published: November 2022

AbstractWe develop two joint tests for the parametric drift and volatility functions of a diffusion model based on empirical processes. One key feature of our joint tests is that they account for different convergence rates of parameter estimators. The tests are of classical Kolmogorov–Smirnov and Cramér–von Mises types, and are asymptotically distribution free. The proposed tests have nontrivial power against a class of local alternatives with different convergence rates for the drift and volatility terms. Monte Carlo simulations show that the tests perform quite well in finite samples and outperform the nonparametric test of Hong and Li. The new tests are applied to EUR/USD exchange rate data and generate some interesting empirical findings that are consistent with our theoretical results and simulation studies.
Evaluation of Potential Food Effects and Drug Interactions With Lansoprazole in Healthy Adult Volunteers Receiving Futibatinib
Authors: Yamamiya Ikuo , Hunt Allen , Yamashita Fumiaki , Sonnichsen Daryl , He Yaohua , Benhadji Karim A. 
Published: November 2022

AbstractFutibatinib, an oral, irreversible fibroblast growth factor receptor (FGFR) 1–4 inhibitor, is being evaluated for FGFR‐aberrant tumors. Two open‐label phase 1 studies evaluated the effects of high‐fat, high‐calorie food and concomitant proton pump inhibitors (PPIs; lansoprazole) on single‐dose futibatinib (20 mg) pharmacokinetics and safety in healthy adults. In the food effect study (N  =  17), subjects received futibatinib under fed and fasted conditions, separated by a 7‐day washout. In the PPI study (N  =  20), subjects received futibatinib alone, underwent a 2‐day washout, and then received lansoprazole 60 mg once daily for 5 days, with futibatinib also administered on day 5. Under fed versus fasted conditions, futibatinib bioavailability was 11.2% lower (area under the plasma concentration–time curve from time 0 to infinity geometric mean ratio 88.8%; 90% confidence interval, 79.8%–98.9%), and median time to maximum plasma concentration was significantly delayed (4.0 vs 1.5 hours; P < .0001). There were no significant differences in futibatinib exposure between futibatinib plus lansoprazole and futibatinib alone. No serious adverse events occurred in either study. These findings suggest that food and PPIs are unlikely to have clinically meaningful impacts on futibatinib bioavailability. Thus, futibatinib may be used with or without food and concomitantly with acid‐reducing agents.
How international immigrants engage in sustainable entrepreneurship in their host countries? The moderating effects of collectivistic cultural values
Authors: Li Ji , Su Qianhong , Zhu Hong , Sun Wei , Zhang Ying 
Published: November 2022

AbstractUsing the in‐group lens of social identity, we study how difference in in‐group identity can lead to difference in sustainable entrepreneurship among international immigrants and their native counterparts. We also test how different dimensions of collectivism, that is, the institutional collectivism (IC) and in‐group collectivism (GC), can influence differently the relationship between in‐group identity and sustainable entrepreneurship. The results of our data analyses demonstrate a significant relationship between the in‐group identity and sustainable entrepreneurship, particularly green participation, at the societal level. Also, IC and GC moderate the relationship between the social identity and sustainable entrepreneurship. Finally, IC and GC also moderate the relationship between sustainable entrepreneurship and related satisfaction, although the directions of the moderating effects are different. Implications for future research and managerial practice are discussed at the end of this article.
Demographic history and gene flow in the peatmosses Sphagnum recurvum and Sphagnum flexuosum (Bryophyta: Sphagnaceae)
Authors: Imwattana Karn , Aguero Blanka , Duffy Aaron , Shaw A. Jonathan 
Published: November 2022

AbstractPopulation size changes and gene flow are processes that can have significant impacts on evolution. The aim of this study was to investigate the relationship of geography to patterns of gene flow and population size changes in a pair of closely related Sphagnum (peatmoss) species: S. recurvum and S. flexuosum. Both species occur in eastern North America, and S. flexuosum also occurs in Europe. Genetic data from restriction‐site‐associated DNA sequencing (RAD‐seq) were used in this study. Analyses of gene flow were accomplished using coalescent simulations of site frequency spectra (SFSs). Signatures of gene flow were confirmed by f4 statistics. For S. flexuosum, genetic diversity of plants in glaciated areas appeared to be lower than that in unglaciated areas, suggesting that glaciation can have an impact on effective population sizes. There is asymmetric gene flow from eastern North America to Europe, suggesting that Europe might have been colonized by plants from eastern North America after the last glacial maximum. The rate of gene flow between S. flexuosum and S. recurvum is lower than that between geographically disjunct S. flexuosum populations. The rate of gene flow between species is higher among sympatric plants of the two species than between currently allopatric S. flexuosum populations. There was also gene flow from S. recurvum to the ancestor S. flexuosum on both continents which occurred through secondary contact. These results illustrate a complex history of interspecific gene flow between S. flexuosum and S. recurvum, which occurred in at least two phases: between ancestral populations after secondary contact and between currently sympatric plants.
Genetic population structure and demographic history of the endemic fish Paralichthys olivaceus of the Northwest Pacific Ocean
Authors: Sun Cheng‐He , Yang Fan , Huang Qi , Zeng Xiao‐Shu , Zhang Ya‐Nan , Li Sha , Yu Jian‐Feng , Zhang Qun 
Published: November 2022

AbstractThe Northwest Pacific marginal waters comprising the South China Sea, East China Sea, Yellow Sea, and the Sea of Japan have unique geomorphic features. The Japanese flounder Paralichthys olivaceus, which is endemic to the Northwest Pacific, has high nutritional, economic, and ecological value. To allow the examination of the demographic history and population structure of the most common P. olivaceus species range over the five marginal seas (East China Sea, Yellow Sea, Bohai Sea, Northwest Pacific Ocean, and the Sea of Japan), the mitochondrial DNA control region of 91 individuals from six populations in China was sequenced. These sequences were combined with 233 sequences from four populations distributed in the Northwestern Pacific Ocean for analysis. Higher levels of nucleotide diversity (0.032 ± 0.016) and haplotype diversity (0.996 ± 0.001) were observed. The peripheral Fuqing population in the East China Sea had the relatively lowest genetic diversity and highest differentiation. Furthermore, when the results of the isolation by distance test, spatial analysis of molecular variation and geographic barrier analysis are also considered, there is a clear need to prioritize resource conservation and enhancement measures in this area. The phylogenetic trees, structure assignment test, and haplotypes network revealed no significant differences in the genealogical structure among ten populations. Mismatch distribution analysis, Bayesian skyline plots, and neutrality tests suggested that P. olivaceus experienced population expansion during the Pleistocene. Ocean currents and climate change play important roles in shaping the geographical distribution and genetic population structure of P. olivaceus.
Record events attribution in climate studies
Authors: Worms Julien , Naveau Philippe 
Published: November 2022

AbstractWithin the statistical climatology literature, inferring the contributions of potential causes with regard to climate change has become a recurrent research theme during this last decade. In particular, disentangling human induced (anthropogenic) forcings from natural causes represents a nontrivial statistical task, especially when the focal point moves away from mean behaviors and goes towards extreme events with high societal impacts. Most studies found in the field of extreme event attributions (EEA) rely on extreme value theory. Under this theoretical umbrella, it is often assumed that, for a given location, temporal changes in extremes can be detected in both location and scale parameters of an extreme value distribution, while its shape parameter remains unchanged over time. This assumption of constant tail shape parameters between a so‐called factual world (all forcings) and a counterfactual one (without anthropogenic forcing) can be challenged due to the fact that important forcing changes could impact large scale atmospheric and oceanic circulation patterns, and consequently, the latter can reshape the full distribution, including its shape parameter that drives extremal behavior. In this article, we study how allowing different tail shape parameters between the factual and counterfactual worlds can affect the analysis of records. In particular, we extend the work of Naveau et al. in which this case was not treated. We also add properties and theoretical inferential results about records in EEA and propose a procedure for model validation. A simulation study of our approach is detailed. Our method is applied to records of yearly maxima of daily maxima of near‐surface air temperature issued from the numerical climate model CNRM‐CM6‐1 of Météo‐France.
Policy learning type shifts during creeping crises: A storyboard of COVID‐19 driven learning in Belgium
Authors: Zaki Bishoy Louis , Pattyn Valérie , Wayenberg Ellen 
Published: November 2022

AbstractUnderstandings of different policy learning types have matured over recent decades. However, relatively little is known about their nonlinear and interactive nature, particularly within crisis contexts. In this article, we explore how two of the most prominent learning types (instrumental and social) shifted and interacted during the COVID‐19 crisis. To do so, we created a policy learning storyboard of the Belgian COVID‐19 policy response over 2 years (from early 2020 to late 2021). Our analysis highlights the relationships between different epochs of instrumental and social learning throughout the crisis and their implications for policy change. Furthermore, while extant policy learning literature often posits that social learning unfolds over relatively long periods (spanning a decade or more), our empirical account shows that within certain conditions, creeping crises can lead to the creation of long‐term crisis policy‐making paradigms and goals. At this level, accelerated social learning can take place and lead to paradigmatic shifts within relatively shorter periods than in noncrisis conditions. Theoretically, our findings enhance our understanding of policy learning types and their relationships with policy change, particularly within crisis contexts.
Dendrophthoe longensisL.J. Singh, A new species ofDendrophthoe(Loranthaceae) from Andaman and Nicobar Islands, India
Authors: Singh Lal Ji 
Published: November 2022

AbstractDendrophthoe longensisL.J. Singh is described as a new species from the Long Island, Andaman and Nicobar Islands, India, and its conservation status is assessed. It is an aerial branch hemi‐parasite onMangifera indicaL. (Anacardiaceae), and serves as a host for caterpillars ofDelias eucharisDrury (Lepidoptera: Pieridae); this could be threats to population of the new species. This new species differs from otherDendrophthoespecies in vegetative morphology, inflorescence architecture, and floral characters. However, it appears apparently close toD. glabrescens(Blakely) Barlow in growth and habit. A detailed description, photographs, distribution, illustrations, and an identification key toDendrophthoespecies of India are provided.
RNA regulation of inflammatory responses in glia and its potential as a therapeutic target in central nervous system disorders
Authors: Guha Abhishek , Husain Mohammed Amir , Si Ying , Nabors L. Burt , Filippova Natalia , Promer Grace , Smith Reed , King Peter H. 
Published: November 2022

AbstractA major hallmark of neuroinflammation is the activation of microglia and astrocytes with the induction of inflammatory mediators such as IL‐1β, TNF‐α, iNOS, and IL‐6. Neuroinflammation contributes to disease progression in a plethora of neurological disorders ranging from acute CNS trauma to chronic neurodegenerative disease. Posttranscriptional pathways of mRNA stability and translational efficiency are major drivers for the expression of these inflammatory mediators. A common element in this level of regulation centers around the adenine‐ and uridine‐rich element (ARE) which is present in the 3′ untranslated region (UTR) of the mRNAs encoding these inflammatory mediators. (ARE)‐binding proteins (AUBPs) such as Human antigen R (HuR), Tristetraprolin (TTP) and KH‐ type splicing regulatory protein (KSRP) are key nodes for directing these posttranscriptional pathways and either promote (HuR) or suppress (TTP and KSRP) glial production of inflammatory mediators. This review will discuss basic concepts of ARE‐mediated RNA regulation and its impact on glial‐driven neuroinflammatory diseases. We will discuss strategies to target this novel level of gene regulation for therapeutic effect and review exciting preliminary studies that underscore its potential for treating neurological disorders.
A diffusion tensor imaging study in schizophrenia patients with clozapine induced obsessive compulsive symptoms
Authors: Bıçakcı Ay Şule , Oğuz Kader K. , Özçelik Eroğlu Elçin , Has Arzu Ceylan , Ertuğrul Aygün 
Published: November 2022

AbstractObjectiveThe aim of this study was to evaluate brain connectivity by diffusion tensor imaging (DTI) in schizophrenia patients with clozapine‐induced obsessive compulsive symptoms (OCS).MethodsEighteen schizophrenia patients, nine of which had clozapine‐induced OCS (Clz‐OCS (+)), 9 without OCS (Clz‐OCS (−)) and 9 healthy controls were included. Psychopathology was evaluated with Positive and Negative Syndrome Scale and Yale‐Brown Obsession and Compulsion Scale in the patient groups. All groups were assesed with neurocognitive tests and DTI.ResultsTract‐Based Spatial Statistics based comparison of DTI revealed lower fractional anisotropy in the genu of corpus callosum (CC), right cingulum, left frontal white matter (WM) in the Clz‐OCS (+) group, compared to controls. Fractional anisotropy was found to be lower in the bilateral occipital WM and higher in the bilateral medial temporal regions, anterior limb of internal capsule, cingulum, frontoparietal peripheral WM, right external capsule and genu of CC in Clz‐OCS (+) patients compared to Clz‐OCS (−).ConclusionsWM integrity in several pathways such as cortico‐striato‐thalamo‐cortical circuitry and orbito‐frontal tracts seems to be affected differently in patients with Clz‐OCS (+). Different neuroplastic effects of clozapine leading to occurrence of OCS in a subgroup of patients is possible, and needs further evaluation by longitudinal follow‐up studies.
The inter‐relatedness and demographic predictors of physical activity, self‐rated health, and mental well‐being: A three‐wave study in secondary school children
Authors: Donnelly Paul , Healy Colm , Paradis Kyle , Horgan Peter , McKay Michael T. 
Published: November 2022

AbstractIntroductionThe World Health Organisation recommends that children and adolescents engage in at least 60 min of moderate‐to‐vigorous physical activity per day. Previous research has shown that physical activity is related to other constructs such as mental well‐being and self‐rated health. This study examined the inter‐relatedness of these constructs in Northern Irish school children.MethodsThis study was a secondary analysis of data gathered as part of a longitudinal study. Participants were n = 1791 adolescents in their final years of secondary (high) school (age range 15–18; female = 64.6%). Data were gathered on three occasions over a 2‐year period on self‐rated health, physical activity, mental well‐being, heavy episodic drinking, lifetime smoking, psychological and somatic symptoms, as well as a range of socio‐demographic measures.ResultsDescriptive results showed extremely low levels of self‐reported physical activity within the past week, with <6% of the sample attaining the WHO guidelines at each wave of data collection. There were significant gender differences on all variables assessed. Results further showed a small‐sized relationship (statistically significant for girls only) between physical activity and mental well‐being. There was also a small‐sized relationship between physical activity and self‐rated health. Notably, effect sizes for the relationship between self‐rated health and both physical activity and mental well‐being were higher. In terms of socio‐demographic predictors of lower physical activity, being female, lifetime cigarette smoking, and higher somatic and psychological symptoms were all statistically significant factors.ConclusionSelf‐rated health emerged as the most important predictor of physical activity among adolescents.
The reciprocal relations between well‐being and maternal and peer warmth in adolescents involved in the juvenile justice system
Authors: Traver Jennifer M. , Dallaire Danielle H. , Frick Paul J. , Steinberg Laurence , Cauffman Elizabeth 
Published: November 2022

AbstractIntroductionAlthough justice system involvement increases the risk of negative outcomes for adolescents, many justice‐involved youth desist from crime as adults (Sampson & Laub, 2005). There are few studies examining predictors of positive development in justice‐involved adolescents. In the current study, we assess the influence of maternal and peer warmth on the development of well‐being in adolescents involved in the US justice system over the course of 5 years.MethodsParticipants included 1216 adolescent males who experienced their first arrest. Interviews were given every year for 5 years. Well‐being was measured using the EPOCH questionnaire (Kern et al., 2016) and relationship warmth was measured using a scale adapted from Conger et al. (1994). Hypotheses were tested using latent curve models with structured residuals.ResultsBaseline levels of well‐being were associated with maternal (β = 0.49, p < .001) and peer warmth, β = 0.52, p < .001. When an individual's maternal warmth was higher than predicted given their maternal warmth trajectory, their subsequent well‐being was higher than expected given their well‐being trajectory, b = 0.07, p < .001. When an individual's peer warmth was higher than predicted, their subsequent well‐being was higher than expected, b = 0.06, p < .001. These relations were reciprocal, such that well‐being also predicted increased maternal and peer warmth.ConclusionsThese findings suggest that increasing maternal or peer warmth may have cascading effects on the well‐being of justice‐involved adolescents. Interventions for justice‐involved youth may benefit from targeting factors that increase positive development for these youth.
FCclasses3: Vibrationally‐resolved spectra simulated at the edge of the harmonic approximation
Authors: Cerezo Javier , Santoro Fabrizio 
Published: November 2022

AbstractWe introduce FCclasses3, a code to carry out vibronic simulations of electronic spectra and nonradiative rates, based on the harmonic approximation. Key new features are: implementation of the full family of vertical and adiabatic harmonic models, vibrational analysis in curvilinear coordinates, extension to several electronic spectroscopies and implementation of time‐dependent approaches. The use of curvilinear valence internal coordinates allows the adoption of quadratic model potential energy surfaces (PES) of the initial and final states expanded at arbitrary configurations. Moreover, the implementation of suitable projectors provides a robust framework for defining reduced‐dimensionality models by sorting flexible coordinates out of the harmonic subset, so that they can then be treated at anharmonic level, or with mixed quantum classical approaches. A set of tools to facilitate input preparation and output analysis is also provided. We show the program at work in the simulation of different spectra (one and two‐photon absorption, emission and resonance Raman) and internal conversion rate of a typical rigid molecule, anthracene. Then, we focus on absorption and emission spectra of a series of flexible polyphenyl molecules, highlighting the relevance of some of the newly implemented features. The code is freely available at http://www.iccom.cnr.it/en/fcclasses/.