bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bioaccumulation Potential of Seagrass (Halophila sp.) for Mercury in the Selected Coastal Areas in Malita, Davao Occidental
Authors: Joy Tuba Junarie , Avenido Pedro , Llameg Marlyn , Elemino Michelle , Cañeda Jopy , Roquero Dexter , Hilis Romeo , Dalogdog Jessa May , Meralles Jamaica , Tabaranza Georgie 
Published: March 2022

This research aims to determine the potential of seagrass Halophila sp. in absorbing mercury in the selected coastal barangays in Malita, Davao Occidental. The study employs a quantitative type of research where strategies focus on quantifying the collection and analysis of data. The study was conducted from October 2020 to December 2021 in the three selected coastal Barangays in Malita, Davao Occidental namely Brgy.Culaman, Brgy. New Argao and Brgy. Tingolo. Transect line quadrat method was used to determine the percent cover and shoot density of seagrass. Using this method, the point of seagrass occurrence up to the outer limit where seagrasses disappears was determined. There were three (3) stations and three (3) transect lines were laid for each station with an interval of 50m. Five (5) quadrats were also laid in the seagrasses along the 50 meter transect line positioned perpendicular to the shoreline. The seagrasses were collected in each quadrat and the samples were transported to Davao Analytical Laboratories, Inc. for mercury analysis. The highest mean percent cover (10.27%), shoot density (128.91 shoots/m2) and Hg accumulation (572.9ppb) was recorded in Brgy. Tingolo, Malita, Davao Occidental while the lowest result was obtained by Brgy. Culaman, Malita, Davao Occidental. Halophila sp. has the capability to accumulate mercury content and exceeds the standard level of 20 ppb. There were no significant differences in the percent cover and Hg accumulation of seagrass Halophila sp. while significant difference is observed in the shoot density. However, there is a positive relationship (.664) between the shoot density and mercury concentration of Halophila sp.
AGGREGATIBACTER (ACTINOBACILLUS) ACTINOMYCETEMCOMITANS E A DOENÇA PERIODONTAL: UMA REVISÃO DA LITERATURA
Authors: França Helene Marie Rodrigues Carvalhal , Santos Renata Souza , Da Costa Elizabeth Maria , Rapp Gisela Estela 
Published: March 2022

A doença periodontal é uma doença inflamatória de origem multifatorial. Papel relevante vem sendo atribuído aos microrganismos na etiologia desta doença. O Aggregatibacter actinomycetemcomitans é um dos mais estudados patógenos associados à doença periodontal. O presente trabalho visa revisar a literatura acerca dos fatores de virulência deste patógeno, que são capazes de impedir a resposta imune do hospedeiro, potencializando assim a destruição dos tecidos periodontais. De acordo com a literatura revisada pode-se apre- ender que o A. actinomycetemcomitans é um microrganismo Gram-negativo, que apresenta diversos fatores de virulência como as leucotoxinas, fímbrias, lipopolissacarídeos, adesinas, vesículas de membrana extracelular, fatores imunossupressores e perturbadores das funções neutrofílicas, da inibição do crescimento das células epiteliais e fibroblásticas, além da ativação das células B policlonais entre outros. Assim, justifica-se que A. actinomycetemcomitans é um importante patógeno periodontal que está associado principalmente com a periodontite agressiva localizada e a sua ocorrência e virulência na saúde ou na doença periodontal são população e sorotipo dependentes. Nesse contexto, o presente trabalho tem como objetivo revisar a literatura acerca deste patógeno,
ASPECTOS CLINICOS DE UMA REABILITAÇÃO COM PRÓTESES FIXAS SOBRE IMPLANTES OSSEOINTEGRADOS: RELATO DE CASO
Authors: De Andrade Cristiano Goés , Corrêa Márcio Plácido , Da Rocha Paulo Vicente Barbosa , Oliveira Fernando José , Júnior Osvaldo Naziazeno de Andrade , Bonfim Eduardo Seixas 
Published: March 2022

Os implantes fazem parte do planejamento dos tratamentos reabilitadores na Odontologia, e quando empregados com critério, tem-se a possibilidade de restituir ao paciente as funções imprescindíveis do sistema estomatognático. A realização de estudos no âmbito dessa temática tem comprovado que os pacientes inválidos orais tem usufruído dos aspectos benéficos das próteses sobre implante, principalmente quando comparado com as próteses totalmente mucosuportadas. Em face destas considerações o presente relato de caso clínico, possui como Objetivo discutir os aspectos de interesse protético na reabilitação de paciente desdentado total com implantes osseointegráveis, descrevendo a execução do tratamento reabilitador protético maxilomandibular através de próteses implantosuportadas e parafusadas. Descrição do Caso: Para isso, realizou-se tratamento seqüencial de uma prótese total implanto suportada e parafusada, composto por duas etapas, sendo uma cirúrgica e uma protética, efetivadas em um intervalo de tempo de quatro meses. Consideração Final: ao final do tratamento observou-se a reabilitação maxilomandibular com próteses totais fixas sobre implantes e a melhora na auto-estima relatada pelo paciente.
IMPACTO DA HALITOSE NA QUALIDADE DE VIDA
Authors: Cotrim Barbára Nascimento , Ribeiro Leila Brito de Queiroz , Ribeiro Érica Del Peloso 
Published: March 2022

A halitose é definida como ar exalado da boca que é ofensivo e desagradável aos outros e para o próprio paciente. A etiologia da halitose ainda é controversa devido à sua natureza multifatorial, porém estudos indicam que aproximada- mente 90% das causas são intra-orais, relacionando-se principalmente com a degradação de matéria orgânica em compostos sulfurados voláteis, pelas bactérias presentes na saliva, biofilme dental, dorso da língua, sulco gengival e bolsas periodontais. Classifica-se a halitose em: halitose verdadeira, pseudo-halitose e halitofobia. Tanto os indivíduos com diagnóstico definido de halitose verdadeira, quanto aqueles com pseudo-halitose ou halitofobia experimentam um grave problema que afeta o seu comportamento social. Surge então a necessidade de se fazer uma abrangente avaliação do impacto do mau odor oral na vida diária dos pacientes. O objetivo deste trabalho é apresentar uma revisão da literatura sobre o impacto da halitose na qualidade de vida dos indivíduos, enfatizando os aspectos psicológicos envolvidos nesta condição, além de apresentar os instrumentos utilizados para a avaliação desse impacto.
APLICAÇÃO DIAGNÓSTICA DE IMAGENS TRIDIMENSIONAIS (3D) NA DOENÇA PERIODONTAL DIAGNOSTIC APPLICATION OF THREE-DIMENSIONAL IMAGES (3D) IN PERIODONTAL DISEASE
Authors: Gomes Viana Mariana Vitória , Cerqueira Júlia Santos , Seixas Pinto Regina Lucia 
Published: March 2022

A doença periodontal é uma doença altamente prevalente na populaçãomundial e se caracteriza pela destruição progressiva do ligamento periodontale reabsorção da crista óssea alveolar interdental e interradicular. Temcomo fatores etiológicos as bactérias do biofilme que associadas aos fatoresgenéticos e ambientais geram uma resposta inflamatória liberam enzimasproteolíticas e danificam o tecido de suporte dental. A avaliação da perdada inserção periodontal por exame clínico é limitada pelos instrumentosde sondagem e condições anatômicas, portanto, imagens radiográficas sãoinevitáveis para determinar a extensão e a gravidade das lesões, pois a representaçãoespacial do osso alveolar tem um valr altamente significativona Periodontia, uma vez que as decisões terapêuticas e as estimativas a longoprazo do prognóstico se fundamentam nele. O exame de imagem maiscomumente utilizado é através de radiografias convencionais, no entantofornece apenas uma visão bidimensional das estruturas tridimensionais,perdendo assim o valor diagnóstico essencial. A imagem tridimensional ou3D, tem se revelado como uma ferramenta clínica, pelo valor altamente informativo.O objetivo do presente trabalho consiste em realizar uma revisãode literatura sobre a aplicação diagnóstica da tomografia computadorizadade feixe cônico em lesões periodontais. Periodontal disease is characterized by the progressive destruction of theperiodontal ligament and alveolar bone Crest resorption interdentallyand interradicular, its etiological factors that biofilm bacteria associatedwith genetic and environmental factors generate an inflammatory responsethat release proteolytic enzymes and damage the fabric of dental support. The evaluation of periodontal insertion loss by clinical examinationis limited by probing instruments and anatomical conditions, therefore,x-rays are inevitable to determine the extent and severity of injuries,because the space representation of the alveolar bone has a significantrole in Periodontics, since therapeutic decisions and long-term estimatesof prognosis are based on it. The most commonly used imaging methodis through conventional x-rays, however, provides only a two-dimensionalview of the three-dimensional structures, thereby losing the essentialdiagnostic value. 3D image has proved as a clinical tool for highly informativevalue. The purpose of this study is to conduct a review of the literatureabout the intended use of cone beam computed tomography inperiodontal lesions.
A Highly Conducting Polymer for Self‐Healable, Printable, and Stretchable Organic Electrochemical Transistor Arrays and Near Hysteresis‐Free Soft Tactile Sensors
Authors: Su Xiaoqian , Wu Xihu , Chen Shuai , Nedumaran Anu Maashaa , Stephen Meera , Hou Kunqi , Czarny Bertrand , Leong Wei Lin 
Published: March 2022

AbstractA stretchable and self‐healable conductive material with high conductivity is critical to high‐performance wearable electronics and integrated devices for applications where large mechanical deformation is involved. While there has been great progress in developing stretchable and self‐healable conducting materials, it remains challenging to concurrently maintain and recover such functionalities before and after healing. Here, a highly stretchable and autonomic self‐healable conducting film consisting of a conducting polymer (poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate), PEDOT:PSS) and a soft‐polymer (poly(2‐acrylamido‐2‐methyl‐1‐propanesulfonic acid), PAAMPSA) is reported. The optimal film exhibits outstanding stretchability as high as 630% and high electrical conductivity of 320 S cm−1, while possessing the ability to repair both mechanical and electrical breakdowns when undergoing severe damage at ambient conditions. This polymer composite film is further utilized in a tactile sensor, which exhibits good pressure sensitivity of 164.5 kPa−1, near hysteresis‐free, an ultrafast response time of 19 ms, and excellent endurance over 1500 consecutive presses. Additionally, an integrated 5 × 4 stretchable and self‐healable organic electrochemical transistor (OECT) array with great device performance is successfully demonstrated. The developed stretchable and autonomic self‐healable conducting film significantly increases the practicality and shelf life of wearable electronics, which in turn, reduces maintenance costs and build‐up of electronic waste.
Evaluation of clinical outcomes with propensity‐score matching for colorectal cancer presenting as an oncologic emergency
Authors: Ogawa Katsuhiro , Miyamoto Yuji , Harada Kazuto , Eto Kojiro , Sawayama Hiroshi , Iwagami Shiro , Iwatsuki Masaaki , Baba Yoshifumi , Yoshida Naoya , Baba Hideo 
Published: March 2022

AbstractAimOncologic emergencies such as perforation and obstruction associated with colorectal cancer are serious diseases that can lead to sepsis. Peritoneal dissemination and other factors may cause cancer progression and worsen the patients’ long‐term prognosis. In this study, we investigated the effect of colorectal cancer presenting as oncologic emergencies on the patients’ clinical course.MethodsWe performed a retrospective study that included 448 patients with colorectal cancer who underwent primary resection at our institution between January 2014 and December 2018. The primary outcome was overall survival, while secondary outcomes were 30‐day mortality and postoperative complications. Cox regression was used to estimate the hazard ratio (HR) for overall survival.ResultsWe identified 56 patients who presented with oncologic emergencies (OE group) and 392 patients who presented with no emergencies (NE group). Propensity‐score matching yielded 56 patients in the OE group and 55 in the NE group with balanced baseline covariates. We found a strong association between overall survival (OS) and oncologic emergencies (HR = 2.4; 95% confidence interval [CI], 1.1‐5.5). The 30‐day mortality was not significantly different between the OE and NE groups (4% vs 0%, P = .25). The incidence of severe postoperative complications (Clavien‐Dindo classification ≥grade 3) did not differ significantly between the groups (25% vs 15%, P = .23).ConclusionColorectal cancer presenting as an oncologic emergency could be safely operated on without increasing the 30‐day mortality rate and the incidence of severe postoperative complications. However, the long‐term prognosis was poor.
Factors associated with prolonged procedure time of embolization for trauma patients
Authors: Aoki Makoto , Matsumoto Shokei , Toyoda Yukitoshi , Senoo Satomi , Inoue Yukio , Yamada Masaki , Fukada Takuya , Funabiki Tomohiro 
Published: March 2022

AimLimited information exists on the factors associated with prolonged procedural time in embolization for trauma patients. We clarified the clinical application of embolization in trauma patients and factors associated with a prolonged procedure time.MethodsMedical records of 162 trauma patients who underwent embolization between January 2007 and December 2020 at a regional trauma care center were reviewed retrospectively. Patients were divided into four embolized body regions: chest, abdomen, pelvis, and other. Patient demographics, trauma mechanism, physiology, trauma severity, embolization procedures, and 30‐day mortality were examined. The outcomes were identifying an embolized body region, embolized arteries, and procedure time. Multiple regression model was created to investigate the factors associated with prolonged procedural time in embolization.ResultsEmbolization was mainly undertaken in pelvic fractures (n = 96, 59%) and abdominal organ injuries (n = 57, 35%) and extended to the chest (n = 17, 10%), and other (n = 20, 12%). Approximately 13% (n = 21) of patients underwent embolization in two or more regions. Embolization was more strictly performed in minor artery injuries, for example, external iliac (n = 15, 16%) and lumbar artery (n = 22, 23%) branches in pelvic fractures, and inferior phrenic artery (n = 2, 3.5%) branches in liver injuries. Multiple regression model indicated that the number of embolized arteries (P = 0.021) and number of embolized regions (P < 0.001) were associated with prolonged procedural time in embolization.ConclusionsEmbolization for trauma patients extended to various trauma regions. In time‐sensitive embolization, emergency interventional radiologists showed superior knowledge of expected embolizing arteries and factors associated with procedure time.
A Nonenzymatic Analog of Pyrimidine Nucleobase Biosynthesis
Authors: Yi Jing , Kaur Harpreet , Kazöne Wahnyalo , Rauscher Sophia A. , Gravillier Louis‐Albin , Muchowska Kamila B. , Moran Joseph 
Published: March 2022

AbstractMetabolic theories for the origin of life posit that inorganic catalysts enabled self‐organized chemical precursors to the pathways of metabolism, including those that make genetic molecules. Recently, experiments showing nonenzymatic versions of a number of core metabolic pathways have started to support this idea. However, experimental demonstrations of nonenzymatic reaction sequences along the de novo ribonucleotide biosynthesis pathways are limited. Here we show that all three reactions of pyrimidine nucleobase biosynthesis that convert aspartate to orotate proceed at 60 °C without photochemistry under aqueous conditions in the presence of metals such as Cu2+and Mn4+. Combining reactions into one‐pot variants is also possible. Life may not have invented pyrimidine nucleobase biosynthesis from scratch, but simply refined existing nonenzymatic reaction channels. This work is a first step towards uniting metabolic theories of life's origin with those centered around genetic molecules.
Metal‐ and Strain‐Free Bioorthogonal Cycloaddition of o‐Diones with Furan‐2(3H)‐one as Anionic Cycloaddend
Authors: Xi Ziwei , Kong Hao , Chen Yu , Deng Jiafang , Xu Wenyuan , Liang Yong , Zhang Yan 
Published: March 2022

AbstractThe development of new bioorthogonal reactions with mutual orthogonality to classic bioorthogonal reactions such as the strain‐promoted azide–alkyne click reaction and the inverse‐electron‐demand Diels–Alder reaction is of great importance in providing chemical tools for multiplex labelling of live cells. Here we report the first anionic cycloaddend‐promoted bioorthogonal cycloaddition reaction between phenanthrene‐9,10‐dione and furan‐2(3H)‐one derivatives, where the high polarity of water is exploited to stabilize the highly electron‐rich anionic cycloaddend. The reaction is metal‐ and strain‐free, which proceeds rapidly in aqueous solution and on live cells with a second‐order rate constant up to 119 M−1 s−1. The combined utilization of this reaction together with the two other widely used bioorthogonal reactions allows for mutually orthogonal labelling of three types of proteins or three groups of living cells in one batch without cross‐talking. Such results highlight the great potential for multiplex labelling of different biomolecules in live cells.
Selective Extraction of Transition Metals from Spent LiNixCoyMn1−x−yO2 Cathode via Regulation of Coordination Environment
Authors: Chang Xin , Fan Min , Gu Chao‐Fan , He Wei‐Huan , Meng Qinghai , Wan Li‐Jun , Guo Yu‐Guo 
Published: March 2022

AbstractThe complexity of chemical compounds in lithium‐ion batteries (LIBs) results in great difficulties in the extraction of multiple transition metals, which have similar physicochemical characteristics. Here, we propose a novel strategy for selective extraction of nickel, cobalt, and manganese from spent LiNixCoyMn1−x−yO2 (NCM) cathode through the regulation of coordination environment. Depending on adjusting the composition of ligand in transition metal complexes, a tandem leaching and separation system is designed and finally enables nickel, cobalt, and manganese to enrich in the form of NiO, Co3O4, and Mn3O4 with high recovery yields of 99.1 %, 95.1 %, and 95.3 %, respectively. We further confirm that the combination of different transition metals with well‐designed ligands is the key to good selectivity. Through our work, fine‐tuning the coordination environment of metal ions is proved to have great prospects in the battery recycling industry.
The story of acyl phosphines: Synthesis, reactivity, and catalytic applications
Authors: Kumar Pawan , Sharma Urvashi , Ananthnag Guddekoppa S. 
Published: March 2022

AbstractAcyl phosphines (R2P–C(O)R) are the tertiary phosphorus compounds having a P–C(O) linkages. Though they are known historically, their literature is not exhaustive mainly due to the vulnerability of P–C(O) bonds toward nucleophilic substitution reactions. However, there is a renewed interest in the synthesis of acyl phosphines and di (acyl) phosphines, recently. Among the methods available for the synthesis, most involve nucleophilic substitutions at carbonyl carbon by phosphorus nucleophile as a customary step. The examples of phosphines possessing two acyl groups (R(O)C–RP–C(O)R) are found more frequently in the literature of late, and most of them are cyclic in nature. The transition‐metal complexes of acyl phosphines and di (acyl) phosphines are moderately explored in literature. However, their catalytic applications are meager. In the current review, the details of syntheses, reactivity, structural features, and catalytic activities of acyl phosphines and bis (acyl) phosphines reported in the last three decades are discussed.
Preliminary design of recyclable epoxy asphalt: Regeneration feasibility analysis and environmental impact assessment
Authors: Zhou Wenyi , Yi Junyan , Pei Zhongshi , Xie Sainan , Feng Decheng 
Published: March 2022

AbstractEpoxy asphalt is a construction material for pavement structures and has been widely used due to excellent durability and longevity characteristics. Although the asphalt phase could be compensated after epoxy asphalt aging, the epoxy resin phase cannot be regenerated at high value due to irreversible covalent cross‐links, resulting in reclaimed epoxy asphalt pavement (epoxy RAP) being employed as aggregate. In this paper, with consideration toward its nonrenewable characteristic, a recyclable epoxy asphalt is designed preliminarily based on the reversible principle of dynamic covalent bonds, thus focusing on the principle of circular economy and reducing environmental impact. The molecular design of recyclable epoxy asphalt was conducted to justify it theoretically. An environmental impacts assessment is used to analyze energy consumption and carbon footprint caused by using reclaimed recyclable epoxy asphalt pavement (recyclable epoxy RAP) in asphalt mixture manufacturing. The analysis of molecular design showed the feasibility of recyclable epoxy asphalt regeneration. And the mixture containing recyclable epoxy RAP could reduce the emission of GHGs by 34% compared with the epoxy RAP, although the consumption of energy is approximate. Based on molecular design and environmental impacts evaluation, the sustainability of recyclable epoxy asphalt is verified.
The impact of facial emotional expression on the effectiveness of charitable advertisements: the role of sympathy and manipulative intent
Authors: Kang In‐Hye , Leliveld Marijke C. , Ferraro Rosellina 
Published: March 2022

AbstractIn charitable advertisements, organizations often display the image of a person in need with different facial emotional expressions. Prior research showed the positive effect of using a sad‐ (vs. happy‐ or neutral‐) faced image in evoking sympathy from viewers. Across five studies (N = 2141), we demonstrate that a sad‐faced image evokes not only sympathy but also an inference about the organization's manipulative intent. Moreover, we show that inference of manipulative intent and sympathy simultaneously mediate the effects of facial expression on donation and on attitude toward the advertising campaign, but in opposing directions. While greater sympathy leads to larger donation, greater inference of manipulative intent lowers donation, together contributing to a null effect of facial expression on donation. In contrast, using a sad‐faced image reduces attitude toward the advertising campaign because the mediating effect of inference of manipulative intent tends to be larger than the mediating effect of sympathy in absolute size. The negative effect of a sad‐faced image on attitude toward the advertising campaign is attenuated when the prominence of the image is low (vs. high). Finally, we show that these effects also emerge in the cause‐related marketing advertising context.
A ratiometric fluorescence strategy based on copper nanoclusters/carbon dots for sensitive detection of doxorubicin
Authors: Li Feifei , Fan Pengfei , Chen Xinbei , Lin Xi , Liu Can , Hu Congcong , Yang Shengyuan , Xiao Fubing 
Published: March 2022

AbstractSensitive detection of doxorubicin (DOX) is critical for clinical theranostics. A novel ratiometric fluorescence strategy based on the inner filter effect (IFE) has been established for the sensitive detection of DOX by designing a ratiometric fluorescence probe. In the presence of DOX, the fluorescence intensity of copper nanoclusters (CuNCs) at 485 nm decreases, and the fluorescence intensity of carbon dots at 560 nm increases. Therefore, DOX can be quantitatively detected by measuring the ratio of the fluorescence intensities at 560 and 485 nm (F560/F485). The F560/F485 ratio exhibits a linear correlation with the DOX concentration in the range from 1.0 × 10−8 M to 1.0 × 10−4 M with the detection limit of 3.7 nM. Furthermore, this method was also successfully applied to the analysis of DOX in human plasma samples, affording an effective platform for drug safety management.