bluuebunny/crossref_metadata_2025_split huggingface dataset:
Calculating the individual probability of successful ocriplasmin treatment in eyes with vitreomacular traction–Validation and refinement of a multivariable prediction model
Authors: Paul Christoph , Müller Hans-Helge , Raber Thomas , Bertelmann Thomas ,   on behalf of the EXPORT study group
Published: July 2022

Purpose
To evaluate a multivariable model predicting the individual probability of successful intravitreal ocriplasmin (IVO) treatment in eyes with vitreomacular traction (VMT).

Methods
Data from three prospective, multicenter IVO studies (OASIS, ORBIT, and INJECT) were pooled. Patients were included if they were treated for a symptomatic VMT without a full-thickness macular hole. A prediction model for VMT resolution using the factors ‘age’ and ‘horizontal VMT diameter’ was validated by receiver operating characteristic analysis and according to grouped prediction after calibration. Multivariable regression analysis was performed to check robustness and explore further improvements.

Results
Data from 591 eyes was included. In the univariate analysis all key factors (age, gender, VMT diameter, lens status, ERM) significantly correlated to treatment success. The prediction model was robust and clinically applicable to estimate the success rate of IVO treatment (AUC of ROC: 0.70). A refinement of the model was achieved through a calibration process.

Conclusion
The developed multivariable model using ‘horizontal VMT diameter’ and ‘age’ is a valid tool for prediction of VMT resolution upon IVO treatment.
Stunting among children under two years in Indonesia: Does maternal education matter?
Authors: Laksono Agung Dwi , Wulandari Ratna Dwi , Amaliah Nurillah , Wisnuwardani Ratih Wirapuspita 
Published: July 2022

Background
Measuring height for age is one of the essential indicators for evaluating children’s growth. The study analyzes the association between maternal education and stunting among children under two years in Indonesia.

Methods
The study employed secondary data from the 2017 Indonesia Nutritional Status Monitoring Survey. The unit of analysis was children under two years, and the study obtained weighted samples of 70,293 children. Besides maternal education, other independent variables analyzed in this study were residence, maternal age, maternal marital status, maternal employment, children’s age, and gender. In the final stage, the study occupied a multivariate test by binary logistic regression test.

Results
The results show the proportion of stunted children under two years in Indonesia nationally is 20.1%. Mothers in primary school and under education categories are 1.587 times more likely than mothers with a college education to have stunted children under two years (95% CI 1.576–1.598). Meanwhile, mothers with a junior high school education have a chance of 1.430 times more than mothers with a college education to have stunted children under two years (95% CI 1.420–1.440). Moreover, mothers with education in the senior high school category have 1.230 times more chances than mothers with a college education to have stunted children under two years (95% CI 1.222–1.238).

Conclusion
The study concluded that the maternal education level was associated with stunting children under two years in Indonesia. The lower the mother’s level of education, the higher the chances of a mother having stunted children under two years.
High-temperature behavior of silicone rubber composite with boron oxide/calcium silicate
Authors: Wang Xiaotian , Qin Yan , Zhao Chenglong 
Published: July 2022

Abstract
The ceramifiable silicone rubber (SR) composite is prepared using boron oxide, calcium silicate, and kaolin as ceramifiable fillers. The effects of the content of CaSiO3/B2O3 on the high-temperature properties of composites are investigated. In the process of decomposition and oxidation of the ceramifiable SR composite in air, B2O3, and low-melting-point glass frit that participate in the formation of the residue network structure in different temperature regions, it continuously produces a liquid phase during the process of the ceramifying transformation. Microscopic images reveal that different structures are formed at different temperatures. The network structure of the ceramic residue becomes increasingly compact with the increase in temperature from 600°C to 800°C, which has a better protective effect on heat transfer and mass loss. At 900°C, with the lattice reconstruction of calcium silicate and the change of crystal structure, volume expansion occurs after cooling, alleviating the volume shrinkage caused by ceramic phase formation in the process of ablation. When the ratio of CaSiO3/B2O3 reaches 1:1 (both are 15 phr), the bending strength and linear shrinkage of the composites reach a satisfactory balance, the bending strength and the shrinkage reach 18.5 MPa and 12.1%, respectively.
lncRNA WT1-AS attenuates hypoxia/ischemia-induced neuronal injury during cerebral ischemic stroke via miR-186-5p/XIAP axis
Authors: You Jianquan , Qian Fei , Huang Yu , Guo Yingxuan , Lv Yaqian , Yang Yuqi , Lu Xiupan , Guo Ting , Wang Jun , Gu Bin 
Published: July 2022

Abstract
This study aimed to investigate the role and mechanism of long non-coding RNA (lncRNA) WT1 antisense RNA (WT1-AS) in cerebral ischemic stroke. The Starbase database and dual-luciferase reporter gene assay were used to analyze the interaction between lncRNA WT1 antisense RNA (lncRNA WT1-AS) and microRNA-186-5p (miR-186-5p). Reverse transcription-quantitative PCR analysis was performed to determine lncRNA WT1-AS and miR-186-5p levels. An oxygen glucose deprivation (OGD)-induced SH-SY5Y cell injury model was established. Cell viability and apoptosis were determined using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide and flow cytometric assays, respectively. Caspase 3 activity was evaluated using a caspase 3 activity detection kit. The results showed that miR-186-5p is a direct target of the lncRNA WT1-AS. In addition, lncRNA WT1-AS levels were downregulated and miR-186-5p levels were upregulated in the blood samples of patients with ischemic stroke and OGD-induced SH-SY5Y cells. WT1-AS overexpression promoted OGD-induced cell viability and reduced the cell apoptosis and caspase 3 activity. However, these effects were reversed by miR-186-5p overexpression. Furthermore, the results demonstrated that the X-linked inhibitor of apoptosis (XIAP) was directly targeted by miR-186-5p. Similarly, transfection with the miR-186-5p inhibitor reduced OGD-induced neuronal damage by upregulating XIAP expression. In conclusion, lncRNA WT1-AS attenuates hypoxia/ischemia-induced neuronal injury in cerebral ischemic stroke through the miR-186-5p/XIAP axis.
Galeno sulla lunghezza di un’epitome da Didimo: De indolentia 24 a BJP (= 121–122 KS). ἐν ἑξακισχιλίοις στίχοις versus ἐν ἓξ βιβλίοις
Authors: Perilli Lorenzo 
Published: July 2022

Abstract
The article proposes a correction of a passage of Galen’s De indolentia, alternative to the one accepted so far. The correction ἐν ἓξ βιβλίοις (“in six books”) is proposed, as alternative to the text hitherto accepted, itself due to a conjectural intervention, ἐν ἑξακισχιλίοις στίχοις (“in six thousand lines”): the manuscript Vlatadon 14 bears an impossible ἐν ἑξακισχιλίοις βιβλίοις (“in six thousand books”). At issue is the length of the epitome made by Galen of the lexicographical works of Didymus on the terminology of ancient comedy. The paper argues that the error of the manuscript could be due to the habit of writing numerals as a single letter accompanied by an apex (here probably a digamma, or perhaps a stigma), and that, when referring to his own works, Galen normally uses the book as his unit of measurement. Finally, it is hypothesized that a length of six thousand stichoi might have been too short for an epitome of the work of Didymus.
Ein überflüssiger und ein nur ansatzweise richtiger Eingriff in den überlieferten Text von Ciceros Schrift De fato
Authors: Weidemann Hermann 
Published: July 2022

Abstract
In the present article, proposed corrections to two passages of Cicero’s treatise De fato are examined. It is shown that, on the one hand, a widely accepted correction for §27 that replaces the well attested reading vera fuerunt instantia ... vera erunt instantia with vera fuerit instantia ... vera erit instantia is unnecessary, and that, on the other hand, my recently suggested correction for §48, which replaces the obviously false reading Nam si atomis ..., illud quoque ... with Aut num, si atomis ..., illud quoque ...?, is deficient and should be improved to Nam si atomis ..., num illud quoque ...?
Holistic approach to the vocational counselling of students with special education needs
Authors: Baranauskienė Ingrida , Radzevičienė Liuda , Valaikienė Aistė , Kossewska Joanna 
Published: July 2022

Vocational counselling is the first and one of the most important stages of prevocational education of pupils with SEN that has influence on successful integration into the labour market and human socialization. In the article the parameters of the ideal model of vocational counselling of pupils with SEN have been analyzed. In identifying the criteria of vocational counselling of pupils with SEN it has been referred to the model of systemic analysis constructed by Le Moigne, described by Baranauskienė, Juodraitis (2008), and in which 5 approaches towards successful participation of persons with disabilities in the labour market have been singled out: approaches towards success from the aspect of structure, aims, influence of environment, development, activity. In the article the data obtained during the research of the Delphi group during which the experts from 12 different countries having scientific and practical work experience of work with pupils with SEN present their approaches towards what criteria should be followed in vocational counselling of pupils with SEN have been analyzed and systemized.
Results of an evaluation study of induction and mentoring for beginning special education teachers: what do they need?
Authors: Sebald Ann M. , Rude Harvey A. 
Published: July 2022

This study reviews the results from a three-year evaluation study of one local school district’s induction and mentoring program for beginning special education teachers in the United States. Data were collected for two years, with an intervention implemented in year three. Results indicate that through strategic and intentional support, the district improved how it supported this unique group of novice professionals. Designing induction and mentoring programs with the intent to maintain and foster the professional development of beginning teachers has implications for supporting the district’s intellectual capital in developing feelings of efficacy in teaching. Connecting induction and mentoring support with teacher preparation programs is discussed as a promising strategy to develop more systematic efforts in these areas. The essential skills for successful mentor teachers in support of learning focused relationships are identified.
Possibilities for development of social education and social educational services for a family at children’s day care centres
Authors: Alifanovienė Daiva , Šapelytė Odeta , Bėčiūtė Nomeda 
Published: July 2022

The article deals with the specificity of social education and socioeducational services for children from socially disadvantaged families provided at children’s day care centres and possibilities of development of these services in the aspect of family members’ social inclusion. The article presents the analysis of qualitative semi-structured interviews. Content analysis targeted at experiences of children’s day care centre professionals (N = 10) highlights the content of learners’ social education at children’s day care centres and of provided socioeducational services for the family, expressed through professionals’ subjective assessment of the current situation and the need for services to be provided.
Guiding Principles for Managed Care Arrangements for the Health of Newborns, Infants, Children, Adolescents and Young Adults
Authors: Carlson Kenneth M. , Berman Suzanne K. , Price Jonathan ,   THE COMMITTEE ON CHILD HEALTH FINANCING
Published: July 2022

Managed care arrangements are an approach to health care delivery in which the payer or other health care entity has policies that affect where care is delivered, what services are covered, and how payment is determined. When policies are intentionally designed, transparently administered, and continuously monitored, they are more likely to improve the population’s utilization of services, access to quality primary and specialty care, and access to appropriate medications. When managed care arrangements are designed well, particularly within evolving payment models, health care can be delivered in a manner that supports the goals of the Quadruple Aim: to reduce per capita costs of health care, to improve the health of populations, to improve the experience of patients receiving care, and to improve the experience of those who are providing care.
The American Academy of Pediatrics (AAP) urges payers and health care entities to use the key principles outlined in this statement when designing and implementing managed care arrangements and policies that cover newborn infants, infants, children, adolescents, and young adults to support the goal of improving the effectiveness of the health care delivery system for the pediatric population. The principles described in this statement are intended to complement those previously published in other AAP policies including “Principles of Child Health Care Financing,” “Scope of Health Care Benefits for Children From Birth Through Age 26,” “Patient- and Family-Centered Care and the Pediatrician’s Role,” and the “AAP Access Principles.”
Research on the Host Country's Regulatory Power in the Situation of the Novel Coronavirus Pneumonia Outbreak
Authors: Su Longge 
Published: July 2022

<p>In the process of combating the Newcastle pneumonia epidemic, shutdown measures taken by countries may harm the legitimate interests of foreign investors, and when foreign investors use the international investment dispute settlement (ISDS) mechanism to arbitrate with the host country, the purpose of international investment agreements (IIAs), which tends to protect the interests of investors, tends to be constantly expanded and used to the neglect of the host country's regulatory power. This is due both to the lack of clarity of certain provisions and to the inherent flaws of the ISDS mechanism. China should actively study the new changes in international investment rules, so that China can more favorably balance the interests of investors and host countries in the process of negotiating international investment agreements, and effectively safeguard the right of national regulation.</p>
The Art of Investing: The Secrets of Gold and Bitcoin Prices
Authors: Zhong Zhuofan , Gao Shijie , Huang Jiahui , Zhou Haoyu , Xu Siyu , Lin Yang 
Published: July 2022

<p>Market traders frequently buy and sell volatile assets with the goal of maximizing total returns. In the complex market, how to predict the general trend of the market more accurately, how to determine the buying point or selling point, to maximize the target income, is the primary consideration of investors more scientifically and reasonably. In this paper, based on the closing price data of bitcoin and gold on Nasdaq from September 11, 2016 to September 10, 2021,<sup>[1]</sup> we first build a LSTM neural network prediction model for sliding sequence prediction, on this basis, we build a trading strategy selection model based on nonlinear programming, and introduce Monte Carlo algorithm to optimize the solution.</p>
Wharton Global Youth Program Competition Summary and Strategy
Authors: Yu Xingyi , Wu Hao , Chen Zhuoling , Yuan Shengkai , Xu Longhao 
Published: July 2022

<p class="16"><span>This is a report paper submitted for the 2021-2022 Global Youth Program of the Wharton School, and we present our investment strategy here. Among more than 2,000 participating teams, we were around the 150th. Therefore, our strategy and report may be helpful for some analysis and further research. </span><span> </span></p><p class="16" align="justify"><span>As the competition ends, o</span><span>ur return is </span><span>- </span><span>3.10 percent with a cash balance of $33,881.28. As such, the p</span><span>ortfolio </span><span>v</span><span>alue</span><span> is $96,899.39. </span><span>T</span><span>he result is largely unexpected, as </span><span>our revenue stably rose and was higher than the average one of the </span><span>SPDR S&amp;P 500 trust</span><span> in the first two-thirds of the competition. Around Nov 10, we suffered a loss of 4 percent and another significant reduction in the last week because of the outbreak of the omicron variant. Therefore, we do not question our strategy. The following content will explain tactics and details in each industry and demonstrate our understanding of investment tools. </span></p>
Language Awareness with a Focus on Lexical Variation
Authors: Tang Minmin 
Published: July 2022

With the continuous development of English language teaching (ELT), language awareness has been studied as a teaching
approach. Vocabulary knowledge is indispensable in all language skills, such as reading and speaking, listening, and writing. It
is one of the constituent elements of language. This article is based on literature review and provides a lexical variation view on
language awareness, and attempts to discuss the variability and flexibility with a focus on lexis, which reflects lexical awareness
on language teaching from the perspective of English teachers. The study shows that Data-driven learning (DDL) approach has
helped EFL learners to build lexical awareness to some degree. Furthermore, three reflections in teachers’ teaching are as follow:
setting themes for peculiar words in each lesson will help students to easily understand the words; adjust teachers’ own language
expression according to the actual response of students constantly; teach the language through the culture.
An Analysis of Stimulating Students’ English Learning Interest of Junior Middle school in Flipped Classroom under “Double Reduction” Policy
Authors: Su Yingqian 
Published: July 2022

Presently, students have much burden of their homework in school, which reduces student’s motivation to learn English.
So, the “Double Reduction” Policy is launched according to people’s appeal. And with the rapid development of national education, English is a part of student’s compulsory courses to learn and also the second language for us, most of students think that it
is tough to learn at the beginning of it. They are not interested in learning it gradually. As of the new national curriculum reform,
the traditional teaching method is no longer adapted to the needs of classroom. So, the new teaching model occurs according to
teaching needs, which is “Flipped Classroom” model. After several demonstrations, it can be turned out this model can save student’s much time and improve their efficiency in acquiring knowledge. At the same time, they can learn and use English freely.
This model swaps the role of classroom and actually motivates learning interest for junior middle school students, it lets students
become the center of it rather than teachers and also gives students many valuable opportunities to perform themselves.
Teaching Reform Measures of Power Electronic Technology Course Based on Hybrid Teaching
Authors: Zhang Xiaoqian 
Published: July 2022

The teaching mode of “hybrid learning” is introduced into the course of power electronics technology, which combines
classroom teaching with network classroom, and uses the teaching video in the existing excellent learning platform to assist theoretical teaching to realize online and offline hybrid teaching. Practice has proved that the “blended learning” teaching model is a
very effective and feasible teaching model, which can be extended to other courses.
Research on Optimal Strategy Scheme based on Neural Network Prediction Model
Authors: Zhang Shuo , Zhu Junan , Qiu Xuan 
Published: July 2022

This paper focuses on the investment plan with the maximum return around the fluctuation of the stock market. First of
all, this paper is based on the neural network model price trend line, and then uses the reverse Bollinger band strategy (CBB model). We calculate the error of the price forecast, draw the residual diagram, and find that the error level of the prediction is within
an acceptable range. The model in this paper has strong expansibility and good robustness. Finally, we summarize the strategies
and results of the model.
Information Shift in E-C Translation of Science and Technology
Authors: Xia Zhenghua 
Published: July 2022

The essence of translation is to convert the information of one language into another. In this process, there exist great
difficulties because of language differences. Therefore, translators should consider the readability of translation and various
compensatory measures should be taken to shift the information of source text to better convey its information to the readers. This
paper mainly discusses information shift in E-C translation of science and technology.
Thoughts on Financial Accounting Management and Teaching Re- form in Colleges and Universities
Authors: Cui Yong 
Published: July 2022

With the development of society, the Internet era is gradually coming, its arrival to the traditional field of education has
brought new opportunities and challenges. Educators have the obligation to understand the development trend and talent demand
of this era. From the perspective of financial accounting management and teaching in colleges and universities, Internet technology
should be applied more, so as to improve the quality of financial accounting management and teaching in colleges and universities.
The main content of this paper is how to use new technology to improve financial accounting management and teaching efficiency
in colleges and universities.
Discussion on the Integrated Guiding Teaching Mode of Design Management for Ability Cultivation
Authors: Wei Huilan , Jiang Tianyi 
Published: July 2022

The special subject attribute of design management determines that its teaching method should be different from the
general art and design courses. Based on the undergraduate teaching practice and experience of design management, this paper
summarizes four main teaching characteristics and teaching experience, in order to obtain exchange and improvement in the field
of art and design teaching.
Application of EDA Technology in Electronic Engineering Design
Authors: Zhang Xiaoyan , Lan Bo , Zhu Yadongyang , Zhang Lugang 
Published: July 2022

The rapid development of EDA technology makes it more and more widely used in modern electronic system design,
including IC design, circuit board wiring, function verification and simulation, and testing.Electronic engineering design is the core
course of cultivating electrical information majors, which helps cultivate students’ engineering ability, practical ability, innovative
consciousness, systematic thinking, etc. Through the application of EDA Technology in all links of course implementation,
including design scheme selection, unit circuit design and system debugging, the correctness and reliability of circuit design are
greatly improved, and the application ability of students’ electronic design software is greatly exercised.
On the Application of Performance Management in Human Resource Management of Modern Enterprises
Authors: Li Jiaying 
Published: July 2022

Entering the stage of social and economic construction and development in the new era, the market competition of
modern enterprises is becoming more and more fierce, so it is necessary to strengthen the scientific management of enterprises.
Using performance appraisal methods to manage enterprise human resources needs to specify the necessary performance appraisal
contents, establish appraisal standards, allocate necessary staff and implement responsibilities, so as to reflect the actual effect of
performance appraisal management.