bluuebunny/crossref_metadata_2025_split huggingface dataset:
A lightweight hardware‐efficient recurrent network for video super‐resolution
Authors: Mo Yannan , Chen Dihu , Su Tao 
Published: July 2022

AbstractRecent studies in the field of video super‐resolution (VSR) have taken great advantage of neural networks and achieved remarkable performance. However, current neural network‐based VSR methods have the following two limitations: (1) sophisticated models usually have high computational overhead and require large caches to store intermediate feature maps and parameters. (2) Bidirectional RNN‐based methods cannot perform VSR until a complete video sequence is available because of the back‐propagation of hidden states. The above two shortcomings make the existing VSR models hard to achieve real‐time VSR. To reduce the computational complexity of the network, the authors propose a lightweight hardware‐efficient recurrent neural network model, LERN, which is combined with depthwise separable convolution and pixel unshuffle. An SRA block is also introduced to help the model get better VSR performance. In order to wisely exploit video inter‐frame information without causing the back propagation of hidden states, the authors introduce a new recurrent architecture that is optimized for video sequences. Besides, the authors design a quantization algorithm to find the optimal fixed‐point representations for each layer. Experimental results demonstrate that LERN can achieve excellent performance with low overhead.
The impact of phase sequence exchange on relay protection and its resolution schemes
Authors: Li Hui , Li Yifan , Huang Shaofeng , Sun Peng , Gao Qi 
Published: July 2022

AbstractPhase sequence exchange (PSE) is a recently developed emergency control technology that uses power electronic devices to quickly change the original phase sequence connection mode of the transmission line from A‐A', B‐B', and C‐C' to A‐C', B‐A', and C‐B', thereby instantly reducing the power angle by 120° to prevent the system from falling out‐of‐step. Here, a comprehensive investigative analysis of the impact of PSE on the protection performance is presented. It is shown that PSE will cause the current differential protection and zero‐sequence current protection to maloperate, and the circuit breaker must be re‐matched after PSE. To solve these problems, it is proposed to install the PSE device between the transformer and the bus‐bar and equip it with independent protection, and protection action resolution schemes are proposed. Finally, based on the RTDS platform, a dynamic simulation test was carried out using a PSE prototype, and the results verify the impact of PSE on protection, as well as the effectiveness of the proposed resolution schemes.
Revisiting viscous transonic decretion disks of Be stars
Authors: Curé Michel , Meneses Rodrigo , Araya Ignacio , Arcos Catalina , Peña Greco , Machuca Natalia , Rodriguez Abigali 
Published: July 2022

Aims. In the context of Be stars, we re-studied the viscous transonic decretion disk model of these stars. This model is driven by a radiative force due to an ensemble of optically thin lines and viscosity considering the Shakura–Sunyaev prescription.
Methods. The nonlinear equation of motion presents a singularity (sonic point) and an eigenvalue, which is also the initial condition at the stellar surface. Then, to obtain this eigenvalue, we set it as a radial quantity and performed a detailed topological analysis. We describe a numerical method for solving either nodal or saddle transonic solutions.
Results. The value of the viscosity α barely determines the location of the sonic point, but it determines the topology of the solution. We found two nodal solutions, which are almost indistinguishable. Saddle solutions were found for lower values of α than required for the nodal solutions. In addition, rotational velocity does not play a determinate role in the velocity (and density) profile, because the viscosity effects collapse all the solutions to almost a unique one in a small region above the stellar surface.
Conclusions. A suitable combination of line-force parameters and/or disk temperature gives the location of the sonic point lower than 50 stellar radii, describing a truncated disk. This could explain the SED turn-down observed in Be stars without needing a binary companion.
Hausärztliche Medizin im digitalen Zeitalter: Szenarien und
Empfehlungen
Authors: Spöhrer Kristina , Buhr Eike , Hein Andreas , Schweda Mark , Scherer Martin 
Published: July 2022

Zusammenfassung
Ziel Der Beitrag nimmt die Situation der hausärztlichen Medizin im
digitalen Zeitalter in den Blick, um künftige Entwicklungsperspektiven
zu erörtern und Handlungsmöglichkeiten aufzuzeigen.
Methodik Es wurde ein strukturierter Verständigungsprozess unter
Einbeziehung relevanter Stakeholder-Perspektiven durchgeführt, der sich
konzeptioneller Ansätze und methodischer Elemente der Szenario-Technik
bediente. Diese Technik ermöglicht auf der Grundlage einer empirisch
informierten Analyse gegenwärtiger Sachlagen und Entwicklungstrends die
Formulierung von Zukunftsszenarien und die Ableitung praktischer
Handlungsempfehlungen.
Ergebnisse In Verlängerung gegenwärtiger Tendenzen im
Bereich der Ärzteschaft, der Patientinnen und Patienten, der technischen
Entwicklung und des Gesundheitswesens wurden ein Best- und ein
Worst-Case-Szenario zur hausärztlichen Medizin im Jahr 2050 entwickelt.
Aus der Analyse und Erörterung der Szenarien ließen sich
Handlungsempfehlungen für die Gegenwart ableiten.
Schlussfolgerung Ausgehend von den entwickelten Szenarien formulieren wir
zwölf Empfehlungen zur künftigen Stärkung einer
hausärztlich-zentrierten Medizin, die eine flächendeckende,
digital unterstützte holistisch-patientenorientierte
Gesundheitsversorgung ermöglicht.
Gibt es einen Zusammenhang zwischen der Zufriedenheit mit der
Unterkunft und der psychischen Gesundheit Geflüchteter in Deutschland?
– Eine Querschnittstudie
Authors: Schönfeld Simone , Sauzet Odile , Razum Oliver 
Published: July 2022

Zusammenfassung
Hintergrund Lärm und fehlende Privatsphäre in
Unterkünften wirken sich möglicherweise negativ auf die
psychische Gesundheit der Geflüchteten aus. Es wird untersucht, ob sich
Zusammenhänge zwischen der Zufriedenheit mit bestimmten
Unterkunftsmerkmalen in Einzel- und Gemeinschaftsunterkünften und der
psychischen Gesundheit nachweisen lassen.
Methode Basis ist die IAB-BAMF-SOEP Befragung aus Deutschland 2016
(n=4491 Geflüchtete). Mittels linearer Regressionsmodelle wird
der Zusammenhang zwischen der psychischen Gesundheit und des Unterkunftstyps
(Einzelunterkunft/Gemeinschaftsunterkunft) als auch der Zufriedenheit
mit der Unterkunft
(allgemein/Essensqualität/Geräuschpegel/Privatsphäre/Freizeitangebote/Anbindung
an den öffentlichen
Nahverkehr/Sicherheit/Deutschkursangebote) geprüft. Es
wird für soziodemographische Faktoren, potenziell traumatische
Erlebnisse vor Ankunft in Deutschland und postmigrantische Expositionen
(u. a. Asylstatus) adjustiert.
Ergebnisse In beiden Unterkunftstypen fand sich eine große
Heterogenität hinsichtlich der untersuchten Merkmale.
Geflüchtete mit einer schlechten psychischen Gesundheit lebten
signifikant häufiger in Gemeinschaftsunterkünften. Wurde
für die genannten Kovariablen kontrolliert, verschwand der Zusammenhang.
Die weiteren acht Unterkunftsmerkmale blieben signifikant mit einer schlechteren
psychischen Gesundheit assoziiert. Die größten Effekte auf die
mentale Gesundheit waren bei den Merkmalen Zufriedenheit mit der Sicherheit,
Privatsphäre und allgemeine Zufriedenheit zu beobachten. Hier belief
sich der Unterschied zwischen Personen, die kaum zufrieden waren, verglichen mit
Personen die sehr zufrieden waren, auf 5–6 Punkte auf der psychischen
Summenskala des SF-12.
Schlussfolgerung Internationale Ergebnisse zum Zusammenhang zwischen
Unterkunftsbedingungen und der psychischen Gesundheit von Geflüchteten
wurden für Deutschland bestätigt. Daraus ergibt sich ein
erhöhter Bedarf an psychischer Gesundheitsversorgung in subjektiv
schlechteren Unterkünften. Zur Identifikation von kritischen
Unterkünften sind Fragen nach der Zufriedenheit (v. a.
Sicherheit, Privatsphäre und allgemeine Zufriedenheit) besser geeignet
als die Einteilung in Einzel- oder Gemeinschaftsunterkünfte, da letztere
sehr unterschiedlich bewertet wurden. Screening-Instrumente für
Unterkünfte können helfen, problematische Unterkünfte zu
identifizieren. Eine umgekehrte Kausalität ist jedoch nicht
abschließend auszuschließen.
Interdisziplinäre Perspektiven zur Bedeutung der
Aerosolübertragung für das Infektionsgeschehen von
SARS-CoV-2
Authors: Held Andreas , Dellweg Dominic , Köhler Dieter , Pfaender Stephanie , Scheuch Gerhard , Schumacher Stefan , Steinmann Eike , Weingartner Ernest , Weinzierl Bernadett , Asbach Christof 
Published: July 2022

ZusammenfassungDie Bedeutung der Aerosolübertragung für das Severe Acute
Respiratory Syndrome Coronavirus Type 2 (SARS-CoV-2) wurde anfangs kontrovers
diskutiert. Mit der Zeit haben sich zur Infektionsminderung jedoch neben
Abstands- und Hygieneregeln auch aerosolphysikalisch begründete
Maßnahmen wie das Tragen von Gesichtsmasken und Lüftung von
Innenräumen als effektiv erwiesen. In einem interdisziplinären
Workshop „Aerosol & SARS-CoV-2“ der Gesellschaft
für Aerosolforschung (GAeF) in Kooperation mit der Deutschen
Gesellschaft für Pneumologie und Beatmungsmedizin (DGP), dem Fachverband
Allgemeine Lufttechnik im VDMA, der Gesellschaft für Virologie (GfV),
der Gesundheitstechnischen Gesellschaft (GG) und der International Society for
Aerosols in Medicine (ISAM) unter der Schirmherrschaft des Robert-Koch-Instituts
(RKI) im März 2021 wurde der Forschungs- und Abstimmungsbedarf zu diesem
Thema aufgegriffen. Wesentliche Grundlagen aus den verschiedenen Disziplinen
sowie interdisziplinäre Perspektiven zur Aerosolübertragung von
SARS-CoV-2 und zu infektionsmindernden Maßnahmen werden hier
zusammengefasst. Abschließend werden offene Forschungsfragen und
dringender Forschungsbedarf dargestellt.
The Diagnosis of Normocalcaemic Hyperparathyroidism is Strikingly
Dissimilar Using Different Commercial Laboratory Assays
Authors: Kalaria Tejas , Fenn Jonathan , Sanders Anna , Yates Alexandra , Duff Christopher , Ashby Helen , Mohammed Pervaz , Ford Clare , Gama Rousseau 
Published: July 2022

AbstractWe assessed the impact of intact parathyroid hormone (iPTH) and adjusted calcium
analyses on Abbott, Roche and Siemens analytical platforms in the diagnosis of
normocalcaemic primary hyperparathyroidism (NCPHPT). These assays are used by
over 85% of clinical laboratories in the UK. Over five months,
consecutive serum samples from outpatients with NCPHPT in the laboratory with
Abbott assays were identified, aliquoted and stored at –80°C.
Frozen aliquots were transported monthly to the other two laboratories. After
thawing, samples were mixed and analysed immediately for calcium, albumin and
iPTH in the laboratories with Abbott, Roche and Siemens analytical platforms.
Adjusted calcium was calculated using the equation used in the respective
laboratory. Diagnostic concordance of iPTH and adjusted calcium were assessed
using manufacturer-provided assay-specific reference intervals and the pathology
harmony reference interval respectively. Fifty-five patients with NCPHPT were
identified using Abbott assays. Of these, 16 (29.1%) and 11
(20.0%) had NCPHPT, 9 (16.4%) and 13 (23.6%) had
hypercalcaemic primary hyperparathyroidism, and 30 (54.6%) and 31
(56.4%) patients had normal results when analysed in laboratories with
Roche and Siemens assays, respectively. The diagnosis of NCPHPT was strikingly
different depending on the commercial assay used. There is a pressing need for
iPTH assay harmonisation and robust reference intervals. Reference intervals may
become invalid if an assay drifts, as exemplified by adjusted calcium in this
study.
Correlation of Serum Estradiol with Bone Mineral Density and Bone
Metabolism in Patients of Postmenopausal Type 2 Diabetes Mellitus Complicated with
Osteoporosis
Authors: Yang Fan , Xu Qiangwei 
Published: July 2022

AbstractType 2 diabetes mellitus (T2DM) complicated with osteoporosis, is a systemic
metabolic disease that affects postmenopausal women. This disease is closely
related to the lack of estrogen. This study aims to demonstrate the correlation
between serum estradiol (E2) levels and osteoporosis, bone mineral density, and
bone metabolism indicators in postmenopausal women with T2DM complicated with
osteoporosis (T2DM-OP). 130 postmenopausal women with T2DM were divided into the
T2DM group (n=62) and the T2DM-OP group (n=68) according to bone
mineral density (BMD). In addition, 80 postmenopausal women with average blood
glucose and bone density were selected as the healthy control group. We compare
the serum levels of E2, bone metabolism indicators, and biochemistry indexes
among the three groups of participants. Compared with the healthy control and
T2DM groups, the BMD and serum level of E2 in T2DM-OP patients were
significantly decreased, while the serum levels of bone alkaline phosphatase,
type I procollagen amino-terminal propeptide, osteocalcin, and
β-collagen C-terminal collagen cross-links were significantly increased.
The serum levels of E2 in the postmenopausal T2DM-OP patients are positively
correlated with BMD and negatively correlated with bone resorption
indicators.
The Effect of Scapular Proprioceptive Neuromuscular Facilitation
Techniques on Pain and Functionality in Patients with Subacromial Impingement
Syndrome: A Randomized Controlled Trial
Authors: Akgüller Tuğba , Akbaba Yıldız Analay , Taşkıran Hanifegül 
Published: July 2022

Abstract
Objective To determine the effectiveness of scapular proprioceptive
neuromuscular facilitation (PNF) techniques in patients with subacromial
impingement syndrome (SIS).
Methods 36 patients were randomized and a 6-week exercise program was
applied to both groups 2 days a week. PNF group also received rhythmic
initiation and repeated stretch PNF techniques in 2 scapula diagonals. Pain and
function were primary outcomes. Active range of motion (ROM), pain pressure
threshold (PPT), active myofascial trigger points (MTrPs), scapular dyskinesis,
anxiety and depression status were secondary outcomes.
Results The improvement in function, internal rotation ROM, PPT, active
MTrPs and patient satisfaction was significantly greater in PNF group than
exercise group (p<0.05). Scapular dyskinesis improved only in PNF group
(p<0.05). Significant improvement in pain, function, ROM, PPT, active
MTrPs, anxiety and depression was found in both groups (p<0.05).
Conclusions Both scapular PNF techniques and standard exercise program are
effective in the treatment of SIS. However, scapular PNF techniques can be added
to the exercise program to further improve function, ROM, PPT, active MTrPs,
scapular dyskinesis, and patient satisfaction.
Endothelial Dysfunction and Platelet Hyperactivation in Diabetic Complications Induced by Glycemic Variability
Authors: Huang Ye , Yue Long , Qiu Jiahuang , Gao Ming , Liu Sijin , Wang Jingshang 
Published: July 2022

AbstractThe development and progression of the complications of chronic diabetes mellitus are attributed not only to increased blood glucose levels but also to glycemic variability. Therefore, a deeper understanding of the role of glycemic variability in the development of diabetic complications may provide more insight into targeted clinical treatment strategies in the future. Previously, the mechanisms implicated in glycemic variability-induced diabetic complications have been comprehensively discussed. However, endothelial dysfunction and platelet hyperactivation, which are two newly recognized critical pathogenic factors, have not been fully elucidated yet. In this review, we first evaluate the assessment of glycemic variability and then summarise the roles of endothelial dysfunction and platelet hyperactivation in glycemic variability-induced complications of diabetes, highlighting the molecular mechanisms involved and their interconnections.
Synthesis of Sulfonylated Cinchona Alkaloids via Zinc-Mediated Sulfonylation of the N-Oxides of the Quinoline Groups
Authors: Han Fu-She , Zhou Jie , Gu Cheng-Yu 
Published: July 2022

AbstractA general and practical method for the synthesis of sulfonylated cinchona alkaloids is presented. The reactions are carried out via Zn-mediated nucleophilic aromatic substitution of the N-oxides of the quinoline core in cinchona alkaloids with a range of sulfonyl chlorides. By careful optimization of the reaction parameters and the procedure, both aromatic and aliphatic sulfonyl chlorides react efficiently with the N-oxides to afford the corresponding sulfonylated products in high yields. In addition, the reaction can be reliably scaled up to gram level. As a result, this method provides a practical route for the synthesis of new cinchona alkaloid derivatives that might be potentially useful compounds, particularly in asymmetric catalysis.
Synthesis of Shape-Persistent meta-Arylene-Butadiynylene Macrocycles with a Different Ring Size
Authors: Pigulski Bartłomiej , Szafert Sławomir , Gulia Nurbey , Małecki Marcin , Pawelczyk Dorota 
Published: July 2022

AbstractA series of meta-phenylene-butadiynylene macrocycles was obtained by homocoupling of terminal bis(ethynyl) precursors using Eglinton conditions. Cyclotetramers and cyclopentamers were isolated from the mixture. However, a hexameric analogue was synthesized using a step-by-step approach. Molecular structures of the resulting macrocycles obtained by X-ray single-crystal analysis manifest conformational diversity, indicating significant flexibility of the meta-arylene-butadiynylene macrocycle conjugated skeleton.
Brain–Computer Interfaces for Awareness Detection, Auxiliary Diagnosis, Prognosis, and Rehabilitation in Patients with Disorders of Consciousness
Authors: Pan Jiahui , Xiao Jun , Wang Jing , Wang Fei , Li Jingcong , Qiu Lina , Di Haibo , Li Yuanqing 
Published: July 2022

AbstractIn recent years, neuroimaging studies have remarkably demonstrated the presence of cognitive motor dissociation in patients with disorders of consciousness (DoC). These findings accelerated the development of brain–computer interfaces (BCIs) as clinical tools for behaviorally unresponsive patients. This article reviews the recent progress of BCIs in patients with DoC and discusses the open challenges. In view of the practical application of BCIs in patients with DoC, four aspects of the relevant literature are introduced: consciousness detection, auxiliary diagnosis, prognosis, and rehabilitation. For each aspect, the paradigm design, brain signal processing methods, and experimental results of representative BCI systems are analyzed. Furthermore, this article provides guidance for BCI design for patients with DoC and discusses practical challenges for future research.
Harmonic Scalpel Hemorrhoidectomy—Open versus Closed: A Comparative Study
Authors: Nagaraju Jagdeesh , Thakur Dileep S. , Somashekar Uday , Verma Amrendra , Kothari Reena , Sharma Dhananjay 
Published: July 2022

Background
Hemorrhoids are one of the frequent presenting complaints in the surgical outpatient department of any hospital. Multiple options are available for the treatment of these based on the grade. Recently, there are many varieties of energy devices being tried for hemorrhoidectomy to decrease the postoperative pain and achieve better hemostasis intraoperatively. This study represented an effort to compare open versus closed method of harmonic scalpel hemorrhoidectomy to determine the differences in terms of operative time, hospital stay, postoperative bleeding, pain, and other complications.

Method
A total of 40 patients, 20 each in open and closed method harmonic scalpel hemorrhoidectomy, were followed up for 6 weeks postoperatively. Early and late outcomes were compared. Incontinence if any was measured with Vaizey incontinence score.

Result
There was significant prolonging of operative time in closed method (30.25 ± 5.49 vs. 22.0 ± 4.70). Postoperative pain was significantly more in open method group compared with closed on days 1, 3, 7, and 21. There was no significant difference between groups in terms of hospital stay, postoperative bleeding, and complications.

Conclusion
Leaving mucosa open after hemorrhoidal tissue excision is comparable to closed in terms of safety complication and is cost effective in terms of operative times and utility of suture materials at the expense of need for analgesics.
The In-Vitro Effect of Homeopathically Prepared Rubus idaeus and 680 nm Laser Irradiation on Cervical Cancer Cells
Authors: Joubert Kelley S. , George Blassan P. , Razlog Radmila , Abrahamse Heidi 
Published: July 2022

Abstract
Background Cervical cancer (CC) is the second leading cancer in women and is the most common in those aged 15 to 44 years. Medicinal plant extracts have been used as homeopathic preparations for health benefits. Rubus idaeus (RI) is used to treat disorders of the female genital tract and produces cytotoxic effects. However, the use of homeopathically prepared RI in combination with low level laser therapy has not previously been explored.
Aim The study aims to investigate the in-vitro effects of homeopathically prepared RI alone and in combination as a potential photosensitizer with Low-level laser irradiation (LLLI) at fluencies of 5, 10, and 15 J/cm2.
Methods HeLa CC cells were treated with RI (D3, D6, and 30cH homeopathic preparations). Cells were then treated with RI IC50 and 680 nm laser diode at 5, 10, and 15 J/cm2 fluencies, and the results compared with untreated control cells. Trypan blue viability, lactate dehydrogenase (LDH) cytotoxicity, and adenosine triphosphate (ATP) proliferation assays were used to analyze the cellular dose-responses along with inverted microscopy, Hoechst staining and Annexin-V/PI staining.
Results RI D3 alone demonstrated an ability to reduce cellular viability to 59% and also to reduce ATP levels. The subsequent combined treatment protocol of RI D3 with all fluencies of laser demonstrated an increase in cellular ATP and increased LDH levels compared with the control.
Conclusion The increased ATP and LDH levels observed in the combined treatment protocol of 680 nm laser and RI D3 at fluencies of 5, 10 and 15 J/cm2, show that the Warburg effect might have been induced in the CC cells – an increase in glucose uptake and the preferential production of lactate, even in the presence of oxygen. More research, including work on other cell lines, needs to be conducted to identify if RI and perhaps a different wavelength of laser irradiation could have potential in inducing cell death in cancer cells.