bluuebunny/crossref_metadata_2025_split huggingface dataset:
Refining a Shugenja Elite
Authors: Clements Frank W. 
Published: August 2022

AbstractIn this article I investigate the reform of Haguro Shugendō undertaken by thebettō(Chief Administrator) Kakujun in concert with the eliteshugenjahouseholds of Tōge during the Kasei (1804–1829) era. I argue that this collaboration demonstrates the centrality of the household to early modern Shugendō and the importance of relationships between those households and powerful institutions such thebettō. Household, status, and both bureaucratized and document-based patron-client relationships—institutions that permeated early modern Japanese society—are crucial for understanding Shugendō. In this light,shugenjacommunities such as Tōge simultaneously displayed the characteristics of both a warrior retainer corps and a socially stratified, self-governing rural village. Kakujun reorganized Haguro’s administrative and social structures, clarifying and documenting its social hierarchy to an unprecedented degree. In the process, established households had their traditional privileges guaranteed or even expanded, resulting in a mutually beneficial relationship between thebettōand local elites.
Local Knowledge for a Prince: A Maqāma on the Miracles of Water
Authors: Pomerantz Maurice A. 
Published: August 2022

Abstract
This article discusses the Maqāma Miyāhiyya (A Maqāma on the Waters) of al-Ḥasan b. Abī Muḥammad al-Ṣafadī as an example of a work that offers geographical knowledge about well-known places to a courtly circle of recipients. The maqāma is found in al-Ṣafadī’s collection of thirty maqāmāt, the Maqāmāt Ǧalāliyya, which was dedicated to the famed ruler of Hama, al-Malik al-Muʾayyad Abū l-Fidāʾ (672/1273–732/1332). The Maqāma Miyāhiyya discusses the rivers of the Mamluk domains in quantitative terms (a comparison of their weights) and then juxtaposes this section with a long poem in raǧaz meter describing the magical properties of springs, lakes, and rivers in Mamluk territory. As such, it represents the way al-Ṣafadī employed local geographical knowledge that he gained through his experience as an administrator in courtly contexts.
A Strange Affliction from Abroad: The Ottoman Chief Imperial Physician Ḥayātīzāde’s Treatise on the Polish Plait (Plica Polonica)
Authors: Yıldız Sara Nur 
Published: August 2022

Abstract
Plica polonica was an early modern disease construct affecting the scalp and hair. Initially associated with Polish populations, the affliction spread throughout southern Europe, as the Ottoman chief imperial physician Ḥayātīzāde’s (d. 1103/1691) treatise on plica polonica indicates. Through a close reading of Ḥayātīzāde’s treatise, this paper explores how the Ottomans responded to a changing disease landscape shaped by the movement of people through warfare and enslavement. It argues that textual medical knowledge circulating in the Mediterranean region was modified according to local sociopolitical and cultural concerns. Ḥayātīzāde recast new Latin medical knowledge not just linguistically but also culturally to fit an Ottoman courtly context. The Ottoman court served as a locus not only for the dissemination of new medical knowledge; it was also a permeable contact zone populated by physicians and translators associated with trans-Danubian political elites. Ḥayātīzāde’s treatise was the product of entangled Ottoman Turkish and Latin learning and knowledge practices shaped in a world of transimperial agents.
The Association between Balanced Time Perspective, Personality Traits, Subjective Well-Being, and Distress during the COVID-19 Pandemic
Authors: Mioni Giovanna , Cellini Nicola , Romola Michela , Bruno Francesco 
Published: August 2022

Abstract
The present study examines whether time perspectives (i.e., Past Negative, Past Positive, Present Hedonistic, Present Fatalistic and Future), Deviation from the Balanced Time Perspective (DBTP), and personality traits (i.e., extraversion, agreeableness, conscientiousness, neuroticism, and openness to experience) are good candidates to explain subjective well-being and psychological distress during the COVID-19 pandemic. Using an online survey, we recruited 1483 participants during the Italian mandatory lockdown. Multiple regressions analysis showed that time perspectives strongly predicted subjective well-being, depression, and stress. Participants highly oriented on Past Positive and Future had higher subjective well-being, while participants highly oriented on Past Negative and Present Fatalistic had lower subjective well-being. Regarding DBTP, participants who greatly deviated from the optimal temporal balance reported lower well-being and were more distressed. Regarding the impact of personality traits, extraversion and neuroticism were the factors that better explained subjective well-being, level of stress, and depression, whereas higher levels of openness were associated with lower levels of depression. Finally, DBTP was a significant moderator in the relationships of extraversion and neuroticism with subjective well-being. Implications for time-perspective theory and practical contributions of the study are discussed.
Deep Brain Stimulation Impact on Voice and Speech Quality in Parkinson's Disease: A Systematic Review
Authors: Baudouin Robin , Lechien Jérôme R. , Carpentier Louise , Gurruchaga Jean‐Marc , Lisan Quentin , Hans Stéphane 
Published: August 2022

AbstractObjectiveDeep brain stimulation (DBS) has considerable efficacy for the motor dysfunction of idiopathic Parkinson's disease (PD) on patient quality of life. However, the benefit of DBS on voice and speech quality remains controversial. We carried out a systematic review to understand the influence of DBS on parkinsonian dysphonia and dysarthria.Data SourcesA PubMed/MEDLINE and Cochrane systematic review was carried out following Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) and Population, Intervention, Comparison, Outcome, Timing, and Setting (PICOTS) statements.Review MethodsThree investigators screened studies published in the literature from inception to May 2022. The following data were retrieved: age, demographic, sex, disease duration, DBS duration, DBS location, speech, and voice quality measurements.ResultsFrom the 180 studies identified, 44 publications met the inclusion criteria, accounting for 866 patients. Twenty‐nine studies focused on voice/speech quality in subthalamic DBS patients, and 6 included patients with stimulation of pallidal, thalamic, and zona incerta regions. Most studies (4/6) reported a deterioration of the vocal parameters on subjective voice quality evaluation. For speech, the findings were more contrasted. There was an important heterogeneity between studies regarding the voice and speech quality outcomes used to evaluate the impact of DBS on voice/speech quality.ConclusionThe impact of DBS on voice and speech quality significantly varies between studies. The stimulated anatomical region may have a significant role since the stimulation of the pallidal area was mainly associated with voice quality improvement, in contrast with other regions. Future controlled studies comparing all region stimulation are needed to get reliable findings.Level of EvidenceLevel III: evidence from evidence summaries developed from systematic reviews
Obstructive Sleep Apnea and Sensorineural Hearing Loss: A Systematic Review and Meta‐analysis
Authors: Kasemsuk Navarat , Chayopasakul Veeruth , Banhiran Wish , Prakairungthong Sarun , Rungmanee Sarin , Suvarnsit Kanokrat , Atipas Suvajana , Keskool Phawin 
Published: August 2022

AbstractObjectivesTo evaluate the associations between obstructive sleep apnea (OSA) and sensorineural hearing loss (SNHL) and the effects of continuous positive airway pressure (CPAP) therapy on SNHL.Data SourcesOvid Medline, Embase, and Scopus databases.Review MethodsA systematic search was done for studies investigating relationships between OSA and SNHL in adults, with manual searches for additional references. The final update was done on December 22, 2021. The Risk of Bias Assessment Tool for Nonrandomized Studies was applied for quality assessments.ResultsThe 20 included studies had a total of 34,442 participants (66% male; mean age, 46.6 years). The OSA group had a significantly worse mean hearing threshold level (HTL) than the control group for midfrequency ranges (500, 1000, 2000 Hz; mean difference, 4.00 dB; 95% CI, 2.40‐5.61) and high‐frequency ranges (4000, 8000 Hz; mean difference, 6.24 dB; 95% CI, 2.99‐9.49). An association between OSA and SNHL was found. When compared with controls, patients with OSA had an odds ratio of 1.52 (95% CI, 1.12‐2.06) for midfrequency hearing impairment and 1.19 (95% CI, 1.05‐1.34) for high‐frequency hearing impairment. However, we did not find significant improvements in midfrequency HTL after CPAP therapy.ConclusionsHTL was significantly poorer among participants with OSA (especially in severe cases) than non‐OSA controls. Studies on patients with OSA with SNHL treated with CPAP did not show significant improvements in midfrequency HTL. Further studies are warranted on these issues.
Pharmacist-Driven Methicillin-Resistant S. aureus Polymerase Chain Reaction Testing for Pneumonia
Authors: Marinucci Victoria , Louzon Patricia R. , Carr Amy L. , Hayes Jillian , Lopez-Ruiz Arnaldo , Sniffen Jason 
Published: August 2022

Background: Nasal colonization with methicillin-resistant Staphylococcus aureus (MRSA) can be detected using nasal swab polymerase chain reaction (PCR) assay and is associated with clinical MRSA infection. The MRSA nasal PCR has a rapid turnaround time and a negative predictive value for MRSA pneumonia of >98%; however, data are limited in critically ill patients. Objective: The purpose of this study is to determine the impact of a pharmacist-driven algorithm, utilizing MRSA PCR nasal screening on duration of anti-MRSA therapy in patients admitted to the intensive care unit (ICU) with suspected pneumonia. Methods: A single-center pre/post study was conducted in 4 ICUs at a large tertiary care community hospital. Adult patients admitted to the ICU initiated on vancomycin or linezolid for pneumonia managed using a pharmacist-driven MRSA PCR algorithm were included in the algorithm cohort. A historical cohort with standard management was matched 1:1 by age, type of pneumonia, and Acute Physiology and Chronic Health Evaluation II (APACHE II) score. The primary outcome was duration of anti-MRSA therapy. Secondary outcomes included MRSA rates, number of vancomycin levels, new onset of acute kidney injury (AKI), ICU length of stay (LOS), hospital LOS, and mortality. Results: Of the 245 patients screened, 50 patients met inclusion criteria for the algorithm cohort and were matched to 50 patients in the historical cohort. The duration of anti-MRSA therapy was significantly lower compared with the historical cohort (47 vs 95 hours; P < 0.001). Secondary outcomes were similar between groups for MRSA rates, new onset of AKI, LOS, and mortality. There were less vancomycin levels ordered in the algorithm cohort (2 vs 3, P = 0.026). Conclusions: A pharmacist-driven MRSA PCR algorithm significantly reduced anti-MRSA duration of therapy in critically ill patients with pneumonia. Future studies should validate these results in critically ill populations and in settings where MRSA pneumonia is more prevalent.
Survival Prediction in Home Hospice Care Patients with Lung Cancer Based on LASSO Algorithm
Authors: Zeng Yicheng , Cao Weihua , Wu Chaofen , Wang Muqing , Xie Yanchun , Chen Wenxia , Hu Xi , Zhou Yanna , Jing Xubin , Cai Xianbin 
Published: August 2022

Purpose The aim of the present study was to develop a nomogram for prognostic prediction of patients with lung cancer in hospice. Methods The data was collected from 1106 lung cancer patients in hospice between January 2008 and December 2018. The data were split into a training set, which was used to identify the most important prognostic factors by the least absolute shrinkage and selection operator (LASSO) and to build the nomogram, while the testing set was used to validate the nomogram. The performance of the nomogram was assessed by c-index, calibration curve and the decision curve analysis (DCA). Results A total of 1106 patients, including 835 (75%) from the training set and 271 (25%) from testing set, were retrospectively analyzed in this study. Using the LASSO regression, 5 most important prognostic predictors that included sex, Karnofsky Performance Scale (KPS), quality-of-life (QOL), edema and anorexia, were selected out of 28 variables. Validated c-indexes of training set at 15, 30, and 90 days were .778 [.737-.818], .776 [.743-.809], and .751 [.713-.790], respectively. Similarly, the validated c-indexes of testing set at 15, 30, and 90 days were .789 [.714-.864], .748 [.685-.811], and .757 [.691-.823], respectively. The nomogram-predicted survival was well calibrated, as the predicted probabilities were close to the expected probabilities. Moreover, the DCA curve showed that nomogram received superior standardized net benefit at a broad threshold. Conclusions The study built a non-lab nomogram with important predictor to analyze the clinical parameters using LASSO. It may be a useful tool to allow clinicians to easily estimate the prognosis of the patients with lung cancer in hospice.
Nomogram predicts atrial fibrillation after coronary artery bypass grafting
Authors: Gong Jingshuai , Wei Yangyan , Zhang Qian , Tang Jiwen , Chang Qing 
Published: August 2022

Abstract
Objective
Using the nomogram to intuitively predict atrial fibrillation after coronary artery bypass grafting. Identify high-risk patients with atrial fibrillation and provide preoperative protective therapy.

Methods
A total of 397 patients that underwent coronary artery bypass grafting were consecutively enrolled. Independent predictors of patients were analyzed by multivariate logistic regression. Two nomograms were constructed to predict postoperative atrial fibrillation.

Results
The incidence of postoperative atrial fibrillation in this study was 29% (115/397). Multivariate Logistic showed that Age, Operative Time > 4 h, Left Atrial Diameter > 40 mm, Mean Arterial Pressure, Body Mass Index > 23 kg/m2, Insulins, and Statins were independently associated with atrial fibrillation after isolated coronary artery bypass grafting. The nomogram of postoperative atrial fibrillation in patients was constructed using total predictor variables (AUC = 0.727, 95% CI 0.673–0.781). The model was internally validated (AUC = 0.701) by K-fold Cross-validation resampling (K = 5, Times = 400). To make an early intervention, the intraoperative information of the patients was excluded. Only 6 variables before surgery were used to establish the brief nomogram to predict postoperative atrial fibrillation (AUC = 0.707, 95% CI 0.651–0.764). The brief model was internally validated (AUC = 0.683) by resampling with K-fold Cross-validation resampling.

Conclusions
These two nomograms could be used to predict patients at high risk for atrial fibrillation after isolated coronary artery bypass grafting.
Assessing the quality of evidence on safety: specifications for application and suggestions for adaptions of the GRADE-criteria in the context of preparing a list of potentially inappropriate medications for older adults
Authors: Mathes Tim , Mann Nina-Kristin , Thürmann Petra , Sönnichsen Andreas , Pieper Dawid 
Published: August 2022

Abstract
Background
Systematic reviews that synthesize safety outcomes pose challenges (e.g. rare events), which raise questions for grading the strength of the body of evidence. This is maybe one reason why in many potentially inappropriate medication (PIM) lists the recommendations are not based on formalized systems for assessing the quality of the body of evidence such as GRADE.
In this contribution, we describe specifications and suggest adaptions of the GRADE system for grading the quality of evidence on safety outcomes, which were developed in the context of preparing a PIM-list, namely PRISCUS.

Methods
We systematically assessed each of the five GRADE domains for rating-down (study limitations, imprecision, inconsistency, indirectness, publication bias) and the criteria for rating-up, considering if special considerations or revisions of the original approach were indicated. The result was gathered in a written document and discussed in a group-meeting of five members with various background until consensus. Subsequently, we performed a proof-of-concept application using a convenience sample of systematic reviews and applied the approach to systematic reviews on 19 different clinical questions.

Results
We describe specifications and suggest adaptions for the criteria “study limitations”, imprecision, “publication bias” and “rating-up for large effect”. In addition, we suggest a new criterion to account for data from subgroup-analyses. The proof-of-concept application did not reveal a need for further revision and thus we used the approach for the systematic reviews that were prepared for the PRISCUS-list.
We assessed 51 outcomes. Each of the proposed adaptions was applied. There were neither an excessive number of low and very low ratings, nor an excessive number of high ratings, but the different methodological quality of the safety outcomes appeared to be well reflected.

Conclusion
The suggestions appear to have the potential to overcome some of the challenges when grading the methodological quality of harms and thus may be helpful for producers of evidence syntheses considering safety.
Differential diagnosis and feature visualization for thyroid nodules using computer-aided ultrasonic diagnosis system: initial clinical assessment
Authors: Xie Fang , Luo Yu-Kun , Lan Yu , Tian Xiao-Qi , Zhu Ya-Qiong , Jin Zhuang , Zhang Ying , Zhang Ming-Bo , Song Qing , Zhang Yan 
Published: August 2022

Abstract
Background
To assess the diagnostic efficacy of the computer-aided ultrasonic diagnosis system (CAD system) in differentiating benign and malignant thyroid nodules.

Methods
The images of 296 thyroid nodules were included in validation sets. The diagnostic efficacy of the CAD system was compared with that of junior physicians and senior physicians, as well as that of the combination diagnosis of the CAD system with junior physicians. The diagnostic efficacy of the CAD system for different sizes of thyroid nodules was compared.

Results
The diagnostic sensitivity and accuracy of the CAD system were higher than those of junior physicians (83.4% vs. 72.2%, 73.0% vs. 69.6%), but the diagnostic specificity of the CAD system was lower than that of junior physicians (62.1% vs. 66.9%). The diagnostic accuracy of the CAD system was lower than that of senior physicians (73.0% vs. 83.8%). However, the combination diagnosis of the CAD system with junior physicians had higher accuracy (81.8%) and AUC (0.842) than those of either the CAD system or junior physicians alone, and comparable diagnostic performance with those of senior physicians. The Kappa was 0.635 in the combination diagnosis of the CAD system with junior physicians, showing good consistency with the pathological results. The accuracy (76.4%) of the CAD system was the highest for nodules of 1–2 cm.

Conclusion
The CAD system can effectively assist physicians to identify malignant and benign thyroid nodules, reduce the overdiagnosis and overtreatment of thyroid nodules, avoid unnecessary invasive fine needle aspiration, and improve the diagnostic accuracy of junior physicians.
Gestational age-based reference ranges for cervical length and preterm birth prediction in triplet pregnancies: an observational retrospective study
Authors: Rodo Carlota , de la Calle María , Maroto Anna , Maiz Nerea , Arévalo Silvia , Garcia-Manau Pablo , Mendoza Manel , Bartha José Luis , Carreras Elena 
Published: August 2022

Abstract
Objectives
To develop gestational age-based reference ranges for cervical length in triplet pregnancies. The secondary objective was to assess the performance of cervical length measured between 18 and 20 + 6 days for the prediction of preterm delivery before 28 and 32 weeks, respectively.

Methods
Observational retrospective study of triplet pregnancies in three Spanish tertiary-care hospitals between 2001 and 2019. Cervical length measurements were consecutively obtained between 15 and 34 weeks of gestation. Pregnancies undergoing multifetal reduction or fetal surgery were excluded.

Results
Two hundred and six triplet pregnancies were included in the final analysis. There was a quadratic decrease in cervical length with gestational age. The median and fifth centiles for cervical length at 20 weeks were 35 and 13 mm. In the prediction of preterm birth < 28 weeks, for a false positive rate of 5%, and 10%, the detection rates were 40.9%, and 40.9%, respectively, and the prediction of preterm birth < 32 weeks, 22.0% and 26.0%, respectively.

Conclusions
In triplet pregnancies, cervical length decreases with gestational age. The performance of cervical length at 18–20 + 6 in screening for preterm birth before 28 and 32 weeks is poor.
Clinical application of low-level laser therapy (Photo-biomodulation therapy) in the management of breast cancer-related lymphedema: a systematic review
Authors: Mahmood Dania , Ahmad Ashfaq , Sharif Faiza , Arslan Syed Asadullah 
Published: August 2022

Abstract
Background
Breast cancer-related lymphedema (BCRL) is a frequent issue that arises after mastectomy surgery in women and compromises physical and mental function. Previously published studies have shown positive effects with the use of Low-level laser therapy in another term Photo-biomodulation therapy (PBM). This research investigated the efficacy of clinical use of LLLT (PBM) in the treatment of metastatic breast cancer-related lymphedema.

Methods
PubMed, PEDro, Medline, and the Cochrane Library were searched for LLLT clinical trials published before October 2021. The methodological quality of randomized trials and the effectiveness of Laser Therapy for BCRL were evaluated. The primary objectives were arm circumference or arm volume, whereas the secondary goals were to assess shoulder mobility and pain severity.

Results
Eight clinical trials were analyzed in total. Typically, the included RCTs had good research quality. At four weeks, there was a considerable reduction in arm circumference/volume, and this continued with long-term follow-up. However, no statistically significant change in shoulder mobility or pain severity was seen between the laser and placebo groups at 0-, 1-, 2-, and 3-month short-term follow-up.

Conclusions
The findings of this comprehensive study demonstrated that LLLT (PBM) was successful in diminishing arm circumference and volume than improving shoulder mobility and pain. Data indicates that laser therapy (PBM) may be a beneficial treatment option for females with PML. Because of the scarcity of evidence, there is a strong need for well-conducted and longer-duration trials in this field.

Trial registration
Details of the protocol for this systematic review were registered on PROSPERO and can be accessed at www.crd.york.ac.uk/PROSPERO/display_record.asp?ID=CRD42022315076.