bluuebunny/crossref_metadata_2025_split huggingface dataset:
Farm Advisory Services and total factor productivity growth in the Irish dairy sector
Authors: Parikoglou Iordanis , Emvalomatis Grigorios , Thorne Fiona , Wallace Michael 
Published: October 2022

AbstractThis paper investigates the impact of the engagement of individual farmers with Farm Advisory Services (FAS) on total factor productivity (TFP) growth, as a relevant indicator of competitiveness under the vision of sustainable intensification. Using farm-level data from the Irish dairy sector between 2008 and 2017, we estimate a random-coefficients stochastic frontier model and construct a TFP growth index, extending Orea (2002) such that the contribution of FAS becomes an additional component of the index. The results indicate that the main driver of TFP growth was technical change and efficiency gains; a negative scale effect slowed down TFP growth, but this impact was counteracted by the positive contribution of FAS to productivity growth.
Prevalence of transthyretin amyloidosis in patients with heart failure with preserved ejection fraction
Authors: Naito T , Nakamura K , Abe Y , Sakuragi S , Kihara H , Okizaki A , Kawai Y , Watanabe H , Yoshikawa M , Takaishi A , Fujio H , Otsuka H , Ogura S , Nomura N , Ito H 
Published: October 2022

Abstract

Background
Heart failure with preserved ejection fraction (HFpEF) currently accounts for up to half of heart failure cases. Although transthyretin amyloidosis (ATTR) can cause HFpEF, the contribution of ATTR to the burden of HFpEF is poorly defined.

Purpose
To clarify the characteristics of ATTR and determine the prevalence of cardiac ATTR in patients with HFpEF.

Methods
This is a multicentre, prospective, observational study in Japan. We enrolled 373 HFpEF (HF+LVEF ≥50%+ 65 &lt; years old) patients who admitted to the Departments of Cardiology from September 2018 to January 2022. A 99mTc-PYP scintigraphy was performed during admission in all eligible patients. The patients divided into 2 groups according to 99mTc-PYP scintigraphy positive (Grade2–3: n=53) or negative (Grade 0–1: n=320). Medical history, laboratory data, echocardiogram, hemodynamic data, treatments compared.

Results
A total of 55 patients (14.2%) showed a moderate to severe up take on the 99mPYP scintigraphy. An endomyocardial biopsy was performed in 32 patients confirming amyloidosis in all cases. There were no differences in age, gender, diabetes, coronary artery disease between the two groups. Although patients with positive PYP group exhibited higher N-terminal pro-brain natriuretic peptide [3.0 (1.7–4.6) vs 3.4 (2.4–4.2); P&lt;0.001)], high sensitive troponin T (0.035±0.038 vs 0.074±0.049; P&lt;0.001), mean left ventricle maximal wall thickness (10.5±1.9 vs 12.5±2.2; P&lt;0.001), clinical overlap between ATTR and other HFpEF forms was high.

Conclusion
ATTR is a disease with significant prevalence in Japanese patients with HFpEF

Funding Acknowledgement
Type of funding sources: None.
Relationship between GDF-15, urinary sodium and markers of renal function in patients with chronic heart failure
Authors: Moreira G R , Avila D X , Di Candia A M , Scaramussa V D , Cavaliere N C , Martins F T , Vieira M P , Villacorta H 
Published: October 2022

Abstract

Background
Patients with heart failure (HF) often have altered renal function. Urinary sodium is a marker of diuretic resistance and is associated with a worse prognosis in HF. Growth differentiation factor-15 (GDF-15) is a marker of oxidative stress and inflammation and is a prognostic predictor in HF.

Objectives
We sought to assess the relationship of GDF-15 with renal function parameters and with urinary sodium in patients with chronic HF.

Methods
We undertook a cross-sectional study of patients with HF from specialized outpatient clinic. Patients with signs and symptoms of HF and LVEF &lt;50% were included. An echocardiogram was performed and blood samples were collected, which were frozen for the final study, where the performance of GDF-15 in the prediction of renal outcomes in HF will be evaluated. The dosage of NT-proBNP was performed using the Elecsys® system (Roche, Basel, Switzerland) and GDF-15 by the sandwich immunoassay method with monoclonal antibodies (Elecsys®, Roche, Basel, Switzerland). Analysis of the relationship between GDF-15 and baseline renal parameters was performed. Correlation analysis was performed between GDF-15 and continuous variables, using the Spearman method.

Results
Sixty-seven patients were included. The etiologies of HF were hypertension, diabetes mellitus, alcoholic cardiomyopathy and idiopathic cardiomyopathy. Forty-one (61.2%) individuals were male, with a mean age of 61±13 years. Median GDF-15 values were 1413 pg/mL (interquartile range 1044–2554). Patients with GDF-15 values above the median had lower urinary sodium values (88 mEq/L [53–121] vs 112 [76–171], p=0.06), lower glomerular filtration rate (GFR) (63.9±29.1 vs 91.2±25 mL/min/1.73 m2, p=0.001) and higher creatinine levels (1.32 mg/dL [0.85–1.71] vs 0.91 [0.78–1.08], p&lt;0.001). There was no significant difference in relation to urinary albumin (21 mg/L [7–126] vs 15.1 [5.8–41], p=0.30). The urinary albumin/creatinine ratio was higher in the group above the median, but did not reach statistical significance (38 mg/g [11–110] vs 12.5 [4.9–29], p=0.13). There was a direct correlation between GDF-15 and creatinine (r=0.56, p&lt;0.001) and an inverse correlation with urinary sodium (r=−0.39, p=0.005) and with GFR (r=−0.55, p&lt;0.001).

Conclusion
GDF-15 correlated with lower urinary sodium levels and worse kidney function in patients with chronic HF. Future studies should address whether GDF-15 is a predictor of worsening renal function overtime.

Funding Acknowledgement
Type of funding sources: None.
From sounding the tocsin to ringing the doorbell: some reflections on Saint Bartholomew as a neighbourhood massacre
Authors: Foa Jérémie 
Published: October 2022

Abstract
What do we know, after so many pages devoted to the lieu de mémoire ‘Saint-Barthélemy’, of the thousands of Protestants thrown into the Seine or flung into the Saône, of those anonymous men, women and children exterminated in the summer and autumn of 1572? What do we know about the executioners during those nights, about those rare people who put their heart and soul into massacring their Huguenot neighbours? The responsibility of Catherine de Médicis or the Guise has been the subject of much interest; the torments of Charles IX and Spanish manipulation have long been scrutinized. This article will eschew these legitimate investigations in order to focus on the humble lives behind that night, the faces of the victims and the names of the killers, to discover who the ordinary actors were in this extraordinary event.
Individual and Societal Shortcomings in Eighteenth-Century German Comedy: A Reassessment
Authors: Wagner Martin 
Published: October 2022

Abstract
To what extent do comedies place the blame for vicious behaviour on the individuals who fail to comply with the norms of their society, or on the structures of society in which individuals act? The traditional understanding is that the moral-philosophical critique of individual behaviour in older comedy was supplanted by social criticism in newer comedy. This article revisits the history of comedy to emphasize the very gradual nature of this development and to shed light on the nuances in the distinction between the critique of individuals and the critique of social structures. The argument is developed through an exemplary analysis of four German-language plays from the eighteenth century: the comedies Die ungleiche Heirath (1743) by Luise Gottsched, Der geschäfftige Müssiggänger (1743) by Johann Elias Schlegel, and Die Soldaten (1776) by J. M. R. Lenz, as well as the farce Voltaire am Abend seiner Apotheose (1778) by Heinrich Leopold Wagner.
Acetamiprid used to preventHylobius abietisdamaging young trees poses a very low risk of causing water contamination provided good forestry practices are followed
Authors: Thomas H , Nisbet T R , Willoughby I H 
Published: October 2022

AbstractA study of chemical runoff following the use of acetamiprid as a pre-treatment and top-up spray to prevent damage from the large pine weevil (Hylobius abietis L.) to young trees was undertaken at a restock site in mid-Wales. The site was specifically selected to pose a high risk of chemical runoff, being a high elevation, headwater catchment with stagnopodzol soils, subject to high rainfall. Water samples were collected before, during and after each treatment from six points around the site, as well as from a nearby stream that acted as a control. Only 1 of the 90 water samples collected detected acetamiprid at levels above the limit of quantification of 0.005 μg l−1 (i.e. 0.000000005 g in 1 l of water) and this appeared to be due to wash-off of residues from the plastic bags the trees had been delivered to the site in, which had been temporarily placed within a dry road drain. The recorded concentration of 0.1022 μg l−1 of acetamiprid was low, being only 20 per cent of the Predicted No Effect Concentration (PNEC) of 0.5 μg l−1. Neither of the top-up spray applications resulted in water contamination at any of the sampling points. The results show that the good forestry practice measures employed were effective in preventing contamination of stream waters by acetamiprid. The use of 10-m buffers between forest drains and receiving streams, as per standard good forestry practice in the UK, should be more than adequate to prevent any chemical runoff contaminating watercourses. However, it is recommended that forest practice is further tightened in relation to the placement and handling of planting bags on site. Bags should not be placed within or near road or forest drains, and they should be removed from the site at the end of each day.
Tectonic deformation at the outer rise of subduction zones
Authors: Yang Jianfeng , Zhao Liang , Li Yang 
Published: October 2022

SUMMARY
Fluids associated with subducting slabs play a crucial role in regulating the dynamics of water discharge, subsequent arc magmatism and intermediate-depth earthquakes in subduction zones. The incoming slab mantle hydration is primarily determined by deep normal faulting due to plate bending at the trench. However, the controlling factors on the outer rise faulting pattern, and the correlation between the inherited outer rise deformation and the intermediate-depth earthquakes, remain to be understood. Here we present high-resolution viscoelasto-plastic numerical models of free subduction for slab bending-related faulting prior to subduction. Our model results show that plastic weakening and friction coefficient of the slab mantle exhibit a significant impact on fault pattern, while plate age and elasticity have a minimal bearing for mature slabs. The brittle bending faults result in large positive pressure gradients in the vertical direction, facilitating seawater infiltrating into the subducting slabs, which corroborates previous numerical models. The faults reaching 15–30 km beneath the Moho coincide with the width of the double seismic zone in subduction zones. We anticipate that water pumped into the slab mantle along the faults, with decreasing water content along the depth, can explain the relatively sporadic lower plane earthquakes.
Optimal stacking of noise cross-correlation functions
Authors: Yang Xiaotao , Bryan Jared , Okubo Kurama , Jiang Chengxin , Clements Timothy , Denolle Marine A 
Published: October 2022

SUMMARY
Cross-correlations of ambient seismic noise are widely used for seismic velocity imaging, monitoring and ground motion analyses. A typical step in analysing noise cross-correlation functions (NCFs) is stacking short-term NCFs over longer time periods to increase the signal quality. Spurious NCFs could contaminate the stack, degrade its quality and limit its use. Many methods have been developed to improve the stacking of coherent waveforms, including earthquake waveforms, receiver functions and NCFs. This study systematically evaluates and compares the performance of eight stacking methods, including arithmetic mean or linear stacking, robust stacking, selective stacking, cluster stacking, phase-weighted stacking, time–frequency phase-weighted stacking, Nth-root stacking and averaging after applying an adaptive covariance filter. Our results demonstrate that, in most cases, all methods can retrieve clear ballistic or first arrivals. However, they yield significant differences in preserving the phase and amplitude information. This study provides a practical guide for choosing the optimal stacking method for specific research applications in ambient noise seismology. We evaluate the performance using multiple onshore and offshore seismic arrays in the Pacific Northwest region. We compare these stacking methods for NCFs calculated from raw ambient noise (referred to as Raw NCFs) and from ambient noise normalized using a one-bit clipping time normalization method (referred to as One-bit NCFs). We evaluate six metrics, including signal-to-noise ratios, phase dispersion images, convergence rate, temporal changes in the ballistic and coda waves, relative amplitude decays with distance and computational time. We show that robust stacking is the best choice for all applications (velocity tomography, monitoring and attenuation studies) using Raw NCFs. For applications using One-bit NCFs, all methods but phase-weighted and Nth-root stacking are good choices for seismic velocity tomography. Linear, robust and selective stacking methods are all equally appropriate choices when using One-bit NCFs for monitoring applications. For applications relying on accurate relative amplitudes, the linear, robust, selective and cluster stacking methods all perform well with One-bit NCFs. The evaluations in this study can be generalized to a broad range of time-series analysis that utilizes data coherence to perform ensemble stacking. Another contribution of this study is the accompanying open-source software package, StackMaster, which can be used for general purposes of time-series stacking.
Aberrant Mucin Expression Profiles Associate With Pediatric Inflammatory Bowel Disease Presentation and Activity
Authors: Breugelmans Tom , Arras Wout , Boen Lauren-Emma , Borms Eliah , Kamperdijk Lisa , De Man Joris , Van de Vijver Els , Van Gils Ann , De Winter Benedicte Y , Moes Nicolette , Smet Annemieke 
Published: October 2022

AbstractBackgroundIntestinal mucosal healing is nowadays preferred as the therapeutic endpoint in inflammatory bowel disease (IBD), but objective measurements at the molecular level are lacking. Because dysregulated mucin expression is suggested to be involved in mucosal barrier dysfunction in IBD, we investigated mucin expression in association with barrier mediators and clinical characteristics in colonic tissue of a pediatric IBD population.MethodsIn this cross-sectional monocentric study, we quantified messenger RNA (mRNA) expression of mucins, intercellular junctions, and cell polarity complexes in inflamed and noninflamed colonic biopsies from pediatric IBD (n = 29) and non-IBD (n = 15) patients. We then validated mucin expression at protein level and correlated mucin mRNA expression with expression of barrier mediators and clinical data.ResultsThe expression of MUC1, MUC3A, MUC4, and MUC13 was increased in the inflamed colon of pediatric IBD patients compared with the noninflamed colon of non-IBD control subjects. Especially MUC13 mRNA expression associated with the expression of barrier mediators, including CDH1, OCLN, and TJP2. MUC1 and MUC3B mRNA expression in combination with calprotectin levels most accurately discriminated IBD patients from non-IBD control subjects (90.6% area under the receiver-operating characteristic curve [AUCROC], 92.0% sensitivity, 73.7% specificity), whereas aberrant mRNA expression of MUC1, MUC3A, MUC4, and MUC13 was distinctive for ulcerative colitis and of MUC3B for Crohn’s disease. Furthermore, expression of MUC3A, MUC3B, and MUC4 correlated with clinical disease activity (ie, Pediatric Ulcerative Colitis Activity Index and Pediatric Crohn’s Disease Activity Index), and of MUC1, MUC2, MUC4, and MUC13 with endoscopic colitis severity in ulcerative colitis patients.ConclusionsColonic mucin expression is disturbed in pediatric IBD patients and associates with disease activity and presentation, suggesting its use as molecular marker to aid in disease diagnosis and management.
Repair of coronary artery ostium with a ring-shaped bovine pericardial patch
Authors: Zhang Dong , Zhu Gui-Jun , Wei Xiang-Yang , Li Bin , Hu Jie , Ma Wei-Guo , Chen Xing-Peng 
Published: October 2022

Abstract
As an approach to coronary artery ostial injury in type A aortic dissection and infective endocarditis, we describe a technique of coronary ostial repair using a ring-shaped bovine pericardial patch. The inner and outer rims of the patch were sutured to the involved coronary ostium (to close the ostial tear) and to the aortic wall (to cover the sinus), respectively. Four patients were successfully managed and computed tomographic coronary arteriogram at follow-up showed patent coronary ostia and arteries. The favourable preliminary results imply that this technique is a simple, safe and effective approach to coronary ostial repair in patients with type A aortic dissection or infective endocarditis.
Staged single-port thoracoscopic R2 sympathicotomy as a reproducible, safe and effective treatment option for debilitating severe facial blushing
Authors: van der Weijde Emma , Kuijpers Michiel , Bouma Wobbe , Mariani Massimo A , Klinkenberg Theo J 
Published: October 2022

Abstract

OBJECTIVES
Our goal was to investigate the safety, feasibility, success rate, complication rate and side effects of staged single-port thoracoscopic R2 sympathicotomy in the treatment of severe facial blushing. Facial blushing is considered a benign condition; however, severe facial blushing can have a major impact on quality of life. When nonsurgical options such as medication and psychological treatments offer no or insufficient relief, surgical treatment with thoracoscopic sympathicotomy should be considered.

METHODS
All patients who underwent a staged thoracoscopic sympathicotomy at level R2 for severe facial blushing between January 2016 and September 2021 were included. Clinical and surgical data were prospectively collected and analysed.

RESULTS
A total of 16 patients with low operative risk (American Society of Anesthesiologists class 1) were treated. No major perioperative complications were encountered. One patient experienced postoperative unilateral Horner’s syndrome that resolved completely after 1 week. Two patients experienced compensatory hyperhidrosis. The success rate was 100%. One patient experienced a slight recurrence of blushing symptoms after 3 years that did not interfere with their quality of life. All patients were satisfied with the results and had no regrets of having undergone the procedure.

CONCLUSIONS
Staged single-port thoracoscopic R2 sympathicotomy is a reproducible, safe and highly effective surgical treatment option with low compensatory hyperhidrosis rates and the potential to significantly improve quality of life in carefully selected patients suffering from severe facial blushing. We would like to increase awareness among healthcare professionals for debilitating facial blushing and suggest timely referral for surgical treatment.
In Search of Gaps between Languages and Wordnets: the Case of Polish-English WordNet
Authors: Rudnicka Ewa , Grabowski Łukasz , Piasecki Maciej , Naskręt Tomasz 
Published: October 2022

AbstractThe results of manual mapping of Polish plWordNet onto English Princeton WordNet revealed a number of gaps and mismatches between those interlinked lexical resources. Preliminary studies have shown that they embrace wordnet-specific and language-specific differences, and in this exploratory study we focus on the latter, also called lacunae. Capitalising on the system of equivalence types and features for linking wordnet senses (Rudnicka et al. 2019), we present a semi-automatic, rule-based diagnostic system developed specifically for systematic detection and classification of gaps and mismatches between wordnets. First, focusing on noun synsets, we aim to identify those network fragments that are the most prone to reveal lexical and referential gaps (Svensén 2009). Second, we attempt to identify areas in an interlinked Polish-English wordnet that require resource expansion or modification of the existing network of inter-lingual relations.
A Genealogical Study of Kuang Qizhao’s An English and Chinese Lexicon (1868)
Authors: Li Rui , Zhang Chun , Xu Hai 
Published: October 2022

Abstract
Embedded in historical and genealogical research, this study investigates the influence of English-Chinese dictionaries compiled by missionaries on Kuang Qizhao’s (1836?–1891?) An English and Chinese Lexicon, compiled in part from those of Morrison, Medhurst and Williams (1868). Drawing on Hartmann’s genealogical approach and the lexicographical findings and linguistic evidence presented in three case studies, we argue that Kuang depended not only on Walter Henry Medhurst’s (1796–1857) English and Chinese Dictionary (1847–48), Samuel Well Williams’ (1812–1884) An English and Chinese Vocabulary (1844) and Robert Morrison’s (1782–1834) English and Chinese dictionary (1822), as indicated in the dictionary title, but also on Wilhelm Lobscheid’s (1822-1893) An English and Chinese Dictionary (1866–69) for his own dictionary. And yet Kuang never acknowledged Lobscheid’s dictionary as one of his source dictionaries. This article discusses the reasons why Kuang failed to acknowledge the importance of Lobscheid’s contribution to his dictionary. It is expected to that the findings we have made will provide insights into the genealogical study of English-Chinese dictionaries in general, as well as confirming Kuang’s remarkable merit in compiling his English-Chinese dictionary in the 19th century.
Temporal Labels and Specifications in Monolingual English Dictionaries
Authors: Norri Juhani 
Published: October 2022

Abstract
The article examines the temporal labels and other specifications of time affixed to twenty-five words in monolingual dictionaries of English. The selection of works studied includes learners’, collegiate, and general-purpose dictionaries, both British and American. In addition, the treatment of the lexemes in the Oxford English Dictionary is noted. The analysis reveals some clear differences between the different types of dictionaries in the overall propensity to furnish temporal labels and other specifications of time. The terminology employed to convey such information varies from one group of dictionaries to another. There is also plenty of variation between the individual volumes inside each group. The target audience of the works examined varies, which explains some of the differences in the treatment of particular lexemes. In general, Osselton’s calls for more consistent terminology in the labelling of old words, presented several decades ago, are still valid. The differences between the labels are not always clear, and the explanations in the front matter of the dictionary may be lacking or unhelpful.