bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design of a software prototype to make a Tour in the Infantery Museum Marine Park using View 360 technology.
Authors: Guzman E. , Hernandez C. , Morales A. , Sánchez S. , Acurero M. 
Published: October 2022

Abstract
Before the arrival of the pandemic due to SARS-CoV-2, the Infantery Museum Marine Park was among the most visited tourist sites in Coveñas, however, due to Colombian decree 457, the museum closed its doors to the visitors, thus avoiding the exposure of the national military heritages that are exposed in it, restricting one of the most important contributions to the educational context in the Caribbean Region. Therefore, the objective of the research is to design the model of a web prototype, using View 360 ° technology, for the remote exhibition of the facilities and heritage of the Infantery Museum Marine Park. The type of research is basic and applied, where a documentary analysis of the 360 ° view technology was carried out, identifying the technical and user requirements for the development of the prototype design, which will integrate 360 ° panoramic photographs and points of access, strengthening the exhibition of the heritages and there was a completely new way for the museum professionals to communicate the exhibits to the public. It is concluded that the proposed prototype meets the functional requirements necessary to solve the problem presented.
Machine learning for population growth modeling through annual CO2 data
Authors: Suárez Gustavo , Hoyos José Daniel , Vallejo Esteban , Arias Julián Andrés 
Published: October 2022

Abstract
This article presents a general framework to model the population growth of Colombia through machine learning, which allows incorporating variables such as CO2 emissions. The data are obtained through the DANE Geoportal and the World Bank portal database. In recent years, several cities in Colombia have experienced an accelerated population and urban growth as a result of an overwhelming increase in the immigrant population, a situation that has been affecting the urban order of the city, mainly due to population confinement, increased environmental pollution, unhealthiness, poverty among other factors.
The population growth prediction fully shows the effects of the fertility rate, mortality, and migration of people from one territory to another, essential factors in determining population and health system conditions. Accurate information can be obtained from population census measurements, a strategy with a high cost; However, the capabilities of machine learning are growing, being also implemented to determine predictions of systems and behaviors in demographic, environmental, and socioeconomic issues, which contributes to the economic and energy-saving that implies the gathering and processing of demographic information for the country.
In this work, to predict population growth, the concept of machine learning was applied, carrying out a data analysis using an Artificial Neural Network (ANN). The results obtained provide a predictive model with the potential to provide regional and governmental entities with suggestions, strategies, and alternatives for studying the population and making decisions for urban redevelopment.
Theoretical study of validation methodologies for energy simulation in nZEB buildings.
Authors: Ascanio-Villabona J G , Lengerke-Pérez O , Sandoval-Rodríguez C L , Rincon-Quintero A D , Jaimes-Quintero K T 
Published: October 2022

Abstract
Validation methodologies play an important role in the analysis of energy simulations in buildings [1], since it is used to reduce the uncertainty of the extrapolations that must be taken into account for any validation study, so there may be various methodologies [2]. This study focuses on developing a state of the art on validation methodologies that can be applied in the analysis of energy simulations for NZEB buildings. First, the review method compiles the documents relevant to the research selected by selection criteria, which indicate whether they are of scientific criteria. Secondly, the methodologies found are reviewed and described, in addition to discussing a series of studies applied to each of the methodologies. Finally, it can be concluded that the application of validation methodologies depends on the purpose of the research, however, Sensitivity analysis is the simplest and most useful method to use in the analysis of building performance, even if it has defects; due to its low computational price, easy execution and interpretation.
Development of a vehicle to automatically load, transport and store the product of a blackberry crop
Authors: Angulo-Julio C.A. , Sandoval-Rodríguez C.L. , Lengerke-Perez O. , Tarazona-Romero B.E , Ascanio-Villabona y J.G. 
Published: October 2022

Abstract
Harvesting the blackberry crop is a delicate process because it must be carried out in the first hours of the day in shallow containers and without overhandling to prevent deterioration of the fruit and its fermentation. In this work a prototype of an automated vehicle is developed to improve the harvesting process of the crop reducing the time without affecting the quality of the blackberry. CAD tools were used to design the structure of the prototype and Arduino boards were used for its control, while communication between the vehicle and the monitoring station was established with Xbee devices. The vehicle moves carrying the harvest product in baskets between the collection points and the warehouse. Automated loading and unloading systems eliminate double handling of the products and require less human intervention. Hence, the implementation of the vehicle for loading, transporting, and unloading the product of the blackberry harvest generates savings in production costs and improves collection times since workers will be able to focus on the selection, harvesting and classification process.
Characterization of learning profiles, according to perception channels, in systems engineering students.
Authors: Romero I J , Morales A D , Sánchez S A 
Published: October 2022

Abstract
This article refers to characterize the predominant cognitive preferences or also called predominant perception channels of first semester students of Systems Engineering, virtual modality, associated to a subject in the area of Computer Science and Technology. The study was carried out with the purpose of providing teachers with a valuable informative tool that serves as a basis for proposing methodological innovations that contribute to face the difficulties of teaching concepts related to computer architecture, taking into account the differences, of individuals, associated to sensory perception, according to the CHAEA model, which has been validated by several authors. The research was descriptive, showing that the predominant profiles in the groups of students who participated in the research are those corresponding to the Theoretical, Pragmatic profile, the former being the predominant one; with a lower tendency for the Reflective style. It is concluded that there is a tendency of diversity towards the 2 channels of perception in which a higher level of preference was observed on the part of the students; therefore, it is suggested that the teaching strategies required for these students be varied according to the predominance found.
Study of paraquat-induced pulmonary fibrosis using biomimetic micro-lung chips
Authors: Xia Jingjing , Xiong Zhuo , Guo Jiaxuan , Wang Yongan , Luo Yuan , Sun Yangyang , Guo Zhongwei , Lu Bingchuan , Zhang Ting , Sun Wei 
Published: October 2022

Abstract
Paraquat (PQ) poisoning induces pulmonary fibrosis in vivo. The pathogenesis of pulmonary fibrosis is complex, which has prevented the development of specific treatments. Pulmonary fibrosis shows several characteristics including epithelial-mesenchymal transition (EMT), fibroblast activation, and extracellular matrix (ECM) deposition. To investigate pulmonary fibrosis, we designed a biomimetic multichannel micro-lung chip to imitate the in vivo interface between the lung epithelium and the lung interstitium. In our model, A549 (lung epithelial cells) and MRC-5 (fetal lung fibroblasts) cells were used to test the efficacy of our chip-based model. Rat tail type I collagen and hyaluronic acid were used to simulate ECM and to provide a 3D microenvironment. The micro-lung chips were cultured with PQ (0, 75, 150, 300, and 400 µM). The viability of A549 and MRC-5 cells significantly decreased with increasing PQ concentrations. There were significant changes in surfactant proteins C (SP-C), alpha smooth muscle actin protein (α-SMA), and vimentin protein levels during PQ-induced pulmonary fibrosis. SP-C levels were decreased in A549 cells, while those of α-SMA and vimentin were increased in A549 cells and MRC-5 cells treated with PQ in the micro-lung chip. We also designed a reference model without interaction between the lung epithelial cells and fibroblasts. Compared to the non-contact model, co-culturing A549 and MRC-5 cells in chips induced more severe EMT in A549 cells after treatment with 75 µM PQ and together defended against PQ-induced damage. Thus, our novel co-culture micro-lung chip that models the lung epithelium and interstitium may provide a new approach for studying lung fibrosis and will facilitate drug development.
Optical Archimedes screw with acceleration of both trajectories and orbital angular momentum
Authors: Zhalenchuck Keren , Marima Daniel , Hadad Barak , Bahabad Alon 
Published: October 2022

Abstract
The optical Archimedes screw is a structured beam of light shown to be useful in conveying airborne particles. Such beams were demonstrated propagating along straight and curved trajectories. Here we demonstrate an optical Archimedes screw where both its linear and angular momenta are accelerating—allowing to both control its trajectory and transverse profile during propagation.
Facile construction of electrospun zein nanofiber loaded with Rana chensinensis skin collagen for wound care after caesarean section surgery
Authors: Zhu Lingping , Lin Chenxiao , Chen Qiaoling 
Published: October 2022

Abstract
Numerous types of biomedical applications have found success using electrospun nanofibers. However, electrospinning techniques overlook Zein fibers favoring monolithic and coaxial fibers. Uniaxial electrospinning was used to construct Zein-structured nanofibers for wound healing, with the phase separation of electrospun polycaprolactone (PCL)/polyvinyl alcohol (PVA) in solution, providing the basis for the investigation. Successful loading of silver nanoparticles (AgNPs) and Rana chensinensis skin collagen (RCSCs) into Zein nanofibers (NFs) improved their bioactivity and antibacterial activity as wound dressings. Zein nanofibers were investigated for their heat conductivity, wettability, and mechanical characteristics. The cytotoxic effects of fabricated nanofibers were examined by using L929 fibroblast cells. Ag@RCSCs-NFs also increased cell migration and proliferation, and the wound scratch model was significantly reduced in size using an in vitro scratch assay. The antibacterial studies showed that the Ag@RCSCs-NFs have a potent antibacterial effect against the tested microbial pathogens (Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus)). Finally, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of PCL/PVP, RCSCs, and Ag@RCSCs against two different bacteria were determined. These results suggest that wound care using Zein nanofibers loaded with RCSCs and AgNPs during cesarean section surgery has great promise.
Research on metal wire blowing mechanism and performance
Authors: Yao Xing-Xing , Feng Jia-Chen 
Published: October 2022

Abstract
A short metal wire can be used as a fuse in a circuit. Using ANSYS software simulations combined with experiments, it was verified that the highest temperature region during the blowing process of the wire and the most blowing position is near the middle When a direct current flow through. A measurement circuit was established to study the effect of fuse length, and current on fuse blowing time. The results show that for 0.05 mm diameter copper wire, the blowing time decreases rapidly with the increase of length when the length is within 1cm under the action of 3.16A direct current, and the blowing time is basically stable at 0.04s when the length exceeds 1 cm due to the limitation of heat transfer distance. The blowing time of copper wire decreases with the increase of current, and the blowing time is basically stable at 0.05s after the current reaches 3.5A; the melting time of three materials (Cu, Ag, Pb-Sb) all satisfy the theoretical prediction that the product of current density squared and time is constant; the equivalent current density is introduced to modify the theoretical formula, which makes the theory and experiment more in agreement. This study provides a more comprehensive description of the blowing time and characteristics of short metal wires under the action of high current (DC) from both theoretical and experimental aspects.
Grain refinement and eutectic modification of A356 casting alloy by adding Al-B-Sr master alloys and its effect on tensile properties
Authors: Eidhed K , Muangnoy P 
Published: October 2022

Abstract
The effects of the grain refinement and eutectic Si modification on tensile properties by using Al-B-Sr master alloys in A356 cast alloy were investigated. Two different master alloys, Al-4%B-1%Sr (4B1Sr) and Al-3%B-3%Sr (3B3Sr), were developed. In microstructure observation, the master alloys were consisted of AlB2, SrB6, AlSrF, KAlF4 and Al4Sr compounds. It should be noted that the α-Al phase also exists in two master alloy. The result showed that the AlB2 area fraction in the 4B1Sr alloy was higher than the 3B3Sr alloy. The 4B1Sr alloy has better efficiencies of α-Al grain refinement and eutectic Si modification than the 3B3Sr alloy, and α-Al grains are refined from 3035 to 312 μm and the eutectic Si is modified from the acicular to fibrous morphology. The tensile properties of 4 wt% treated with 4B1Sr alloy has higher UTS and elongation compared to the treated with 3B3Sr alloy.
Oil Red O Staining of Pulmonary Macrophages in Bronchoalveolar Lavage Specimens Is Not Specific for Vaping-Associated Lung Injury
Authors: Jebastin Thangaiah Judith , Booth Christine N , Brainard Jennifer A , Elsheikh Tarik M , Reynolds Jordan P , Ondrejka Sarah L , Thilagar Bright P , Mukhopadhyay Sanjay , Doxtader Erika E 
Published: October 2022

Abstract

Objectives
Oil Red O (ORO) positivity in bronchoalveolar lavage (BAL) fluid macrophages in the setting of e-cigarette, or vaping, product use–associated acute lung injury (EVALI) has been frequently requested by clinicians based on rare reports and subsequent US Centers for Disease Control and Prevention guidelines. The aim of this study was to determine the specificity of ORO staining in BAL specimens with disease states other than EVALI.

Methods
Consecutive BAL specimens (October-December 2019) were stained with ORO. The lipid-laden macrophage index (LLMI) was calculated for each case.

Results
We studied BAL samples from 50 patients. Indications for BAL were surveillance bronchoscopy for lung transplantation (27/50), suspected infection (12/50), sarcoidosis/suspected sarcoidosis (3/50), nodules or ground-glass opacities (3/50), hemoptysis (2/50), asthma or eosinophilic pneumonia (2/50), and idiopathic pulmonary fibrosis (1/50). ORO staining was seen in BAL fluid macrophages in 45 of 50 cases (focal in 18, moderate in 23, diffuse in 4); LLMI ranged from 0 to 218. Using a threshold of LLMI of 85 or higher as positive, ORO was positive in 7 of 50 (14%) cases (range, 85-218).

Conclusions
ORO staining in BAL fluid macrophages is not specific for EVALI. Even when an LLMI of 85 or higher is used as a threshold for positivity, ORO positivity occurs in a significant subset of non–vaping-related cases.
Pockets of Possibility: Students of English in Diverse, Multilingual Secondary Schools in Austria
Authors: Erling Elizabeth J , Brummer Michael , Foltz Anouschka 
Published: October 2022

AbstractThis study provides a counter-narrative to commonly found deficit discourses about LX English learners from migration backgrounds in Europe. A questionnaire was conducted with 108 middle school students and 100 high school students in Austria in a context which has been relatively unexplored: non-elite, linguistically diverse small-town schools. Here, students are meeting their learning outcomes for English at a higher success rate than the national average, and this success in LX learning aligns with high reported levels of home language proficiency. Responses indicate that linguistically diverse students are more likely to succeed when they feel comfortable in the English classroom and actively participate in lessons. Students’ success is also related to their teachers showing an interest in their linguistic and cultural backgrounds. Findings thus suggest that this context is allowing for the creation of ‘pockets of possibility’ where teachers take on the rudiments of a translanguaging stance and create safe spaces in which students perform their multilingual identities as valued and welcome members of the classroom community.
Evaluation of efficiency prediction algorithms and development of ensemble model for CRISPR/Cas9 gRNA selection
Authors: Chen Yuhao , Wang Xiaowei 
Published: October 2022

Abstract

Motivation
The CRISPR/Cas9 system is widely used for genome editing. The editing efficiency of CRISPR/Cas9 is mainly determined by the guide RNA (gRNA). Although many computational algorithms have been developed in recent years, it is still a challenge to select optimal bioinformatics tools for gRNA design in different experimental settings.

Results
We performed a comprehensive comparison analysis of 15 public algorithms for gRNA design, using 16 experimental gRNA datasets. Based on this analysis, we identified the top-performing algorithms, with which we further implemented various computational strategies to build ensemble models for performance improvement. Validation analysis indicates that the new ensemble model had improved performance over any individual algorithm alone at predicting gRNA efficacy under various experimental conditions.

Availability and implementation
The new sgRNA design tool is freely accessible as a web application via https://crisprdb.org. The source code and stand-alone version is available at Figshare (https://doi.org/10.6084/m9.figshare.21295863) and Github (https://github.com/wang-lab/CRISPRDB).

Supplementary information
Supplementary data are available at Bioinformatics online.
The effect of background music on stress in the operating surgeon: scoping review
Authors: Narayanan Anantha , Pearson Lydia , Fisher James P , Khashram Manar 
Published: October 2022

Abstract

Background
Despite the ubiquitous sounds of music playing in operating theatres (OTs) around the world, the effect that music has on intraoperative clinician stress is ill-defined. In the present scoping review the aim was to map the available evidence for the effect of background music in the OT on the experience of stress in the operating surgeon.

Methods
The present review was conducted in accordance with the PRISMA Protocols for Scoping Reviews. Using Embase, MEDLINE, and the Cochrane databases, peer-reviewed research studies reporting the effect of intraoperative background music on an outcome measure of clinician stress or respondent perceptions on this effect were included.

Results
A total of 4342 studies were screened and 15 studies met the inclusion criteria, of which 10 were interventional studies, and five were observational survey-based studies. Of the 10 interventional studies, four showed reduced anxiety and mental workload scores with music, although only two demonstrated a significant improvement in a physiological outcome. The survey-based studies generally reported a positive perception among surgeons and theatre staff towards the effect of music on OT stress.

Conclusion
While there is generally a positive perception towards intraoperative music and surgeon stress, there are few objective physiological and psychological data to support this. Studies were varied in their design. The present review can be used to guide future experimental, observational, and mixed-method research on this topic.
Routine pathologic evaluation of circular stapler anastomotic rings is not useful after resection for colorectal cancer: retrospective study and systematic review with meta-analysis
Authors: Holden James R , McIntosh Pam , Johnson Garrett G R J , Park Jason , Hochman David J , Vergis Ashley , Yip Benson , Helewa Ramzi M , Hyun Eric 
Published: October 2022

Abstract

Background
Circular staplers are commonly used for reconstruction after radical resection for colorectal cancer. Pathological analysis of the anastomotic rings is common practice, although the benefits are unclear. The purpose of this study was to evaluate the usefulness of routine histopathological analysis of anastomotic rings in an original series and in a systematic review of the literature.

Method
The retrospective study was performed at two university-associated academic hospitals in Winnipeg, Canada, including patients investigated for colorectal cancers (within 30 cm of the anal verge) who underwent resection between 2007 and 2020. The systematic review involved Ovid MEDLINE, Embase, Scopus, and Web of Science databases, selecting for adult human studies involving analysis of anastomotic rings in elective colorectal cancer resections. The main outcome measure was the proportion of patients with cancer in the anastomotic ring specimens. The frequency of benign pathology findings and changes to patient management were also examined.

Results
Out of 673 eligible patients, 487 were included in the retrospective analysis. No patients had cancer within the anastomotic ring specimens. Twenty-five patients (5.1 per cent) had benign pathological findings within the anastomotic ring specimens, and patient management was never affected. In the systematic review, 27 articles were included in the final analysis out of 5848 records reviewed. The rate of cancer within anastomotic ring specimens was 0.34 per cent, and the rate of change in patient management was 0.19 per cent.

Conclusion
The likelihood of finding cancer within anastomotic rings is rare and their histopathological examination seldom changes patient management.
Effect of sedatives or anesthetics on the measurement of resting brain function in common marmosets
Authors: Muta Kanako , Hata Junichi , Kawaguchi Naoki , Haga Yawara , Yoshimaru Daisuke , Hagiya Kei , Kaneko Takaaki , Miyabe-Nishiwaki Takako , Komaki Yuji , Seki Fumiko , Okano Hirotaka James , Okano Hideyuki 
Published: October 2022

AbstractCommon marmosets are promising laboratory animals for the study of higher brain functions. Although there are many opportunities to use sedatives and anesthetics in resting brain function measurements in marmosets, their effects on the resting-state network remain unclear. In this study, the effects of sedatives or anesthetics such as midazolam, dexmedetomidine, co-administration of isoflurane and dexmedetomidine, propofol, alfaxalone, isoflurane, and sevoflurane on the resting brain function in common marmosets were evaluated using independent component analysis, dual regression analysis, and graph-theoretic analysis; and the sedatives or anesthetics suitable for the evaluation of resting brain function were investigated. The results show that network preservation tendency under light sedative with midazolam and dexmedetomidine is similar regardless of the type of target receptor. Moreover, alfaxalone, isoflurane, and sevoflurane have similar effects on resting state brain function, but only propofol exhibits different tendencies, as resting brain function is more preserved than it is following the administration of the other anesthetics. Co-administration of isoflurane and dexmedetomidine shows middle effect between sedatives and anesthetics.