bluuebunny/crossref_metadata_2025_split huggingface dataset:
Variation characteristics and the impact of urbanization of extreme precipitation in Shanghai
Authors: Mou Yali , Gao Xichao , Yang Zhiyong , Xu Tianyin , Feng Jie 
Published: October 2022

AbstractWith the rapid development of urbanization, the characteristics of extreme precipitation in urban areas have changed significantly. Revealing the spatial and temporal distribution of extreme precipitation under changing environment is the basis of scientific response to the urban flood. Trends of extreme precipitation at 95% and 99% thresholds in Shanghai and the influence of urbanization on them were analyzed. The results show that: (1) The precipitation threshold limit value for each site are 5.7 ~ 6.3 mm at 95% with a variation factor of 0.04, and 14.3 ~ 17.16 mm at 99% with a variation factor of 0.06. The precipitation thresholds under 99% conditions were more significantly different among stations. (2) The extreme precipitation at each site has been increasing over the past 50 years, and the growth rates of 95% and 99% extreme precipitation are 8.02~11.46%/10a and 7.11~16.86%/10a, respectively. The growth rate of extreme precipitation is significantly higher than that of average precipitation, while the extreme part of the precipitation probability distribution increases considerably. There is a strong variability in extreme precipitation in this region, while the 99% threshold precipitation varies more. (3) The extreme precipitation in Shanghai is significantly positively correlated with the urbanization of the area around the site. Urbanization has an increasing effect on regional extreme precipitation, with more extreme precipitation and greater growth rate in highly urbanized areas.
Compost from willow biomass (Salix viminalis L.) as a horticultural substrate alternative to peat in the production of vegetable transplants
Authors: Adamczewska-Sowińska Katarzyna , Sowiński Józef , Jamroz Elżbieta , Bekier Jakub 
Published: October 2022

AbstractWillow (Salix viminalis L.) is a species well adapted to the environment conditions of central Europe. It is mainly cultivated for energy purposes as solid fuel. In this study, an evaluation of its suitability for other purposes was made using a 4-year old short rotation coppice (SRC) willow regrowth to produce chipped biomass which was composted. Four composting methods were used: without additives (WC), with the addition of nitrogen to narrow the C:N ratio (WN), with the addition of mycelium (WPG) and with the addition of mycelium and nitrogen (WPGN). A mixture of WC and WPGN composts was also prepared at 75:25% and 50:50% by volume. Composts, different proportion (25, 50 and 75%) of peat (SM) were evaluated for suitability as a substrate for tomato and cucumber transplant production. Tomato transplants produced in the medium were prepared from mixtures of willow composts (WPGN + WC(1) and WPGN + WC(2) and these mixtures with peat (WPGN + WC(1):SM and WPGN + WC(2):SM) were characterised as having the best parameters: plant height, lateral leaf span and number of leaves. Similarly, for cucumber transplants, better growth conditions than in peat substrate were obtained in the variant WPGN + WC(1) and WPGN + WC(1):SM. The addition of nitrogen to the composted biomass positively influenced the composting process. N concentration in the substrate was too high and toxic for the growth of tomato and cucumber transplants. At the end of the tomato and cucumber experiment, the nitrate content was 1510 and 2260 mg dm−3, respectively, in the WN substrate. Similarly, the high N–NO3− content in the composted willow substrate with the addition of nitrogen and mycelium did not promote the growth of tomato and cucumber. Based on this research at least 25% of the mass of the peat can be replaced by different willow composts without having an adverse impact on seedling growth and with some of the willow compost mixtures this could be as high as 50%.
A paleo-perspective on West Antarctic Ice Sheet retreat
Authors: Bart Philip J. , Kratochvil Matthew 
Published: October 2022

AbstractGeological records of ice sheet collapse can provide perspective on the ongoing retreat of grounded and floating ice. An abrupt retreat of the West Antarctic Ice Sheet (WAIS) that occurred during the early deglaciation is well recorded on the eastern Ross Sea continental shelf. There, an ice shelf breakup at 12.3 ± 0.6 cal. (calibrated) kyr BP caused accelerated ice-mass loss from the Bindschadler Ice Stream (BIS). The accelerated mass loss led to a significant negative mass balance that re-organized WAIS flow across the central and eastern Ross Sea. By ~ 11.5 ± 0.3 cal kyr BP, dynamic thinning of grounded ice triggered a retreat that opened a ~ 200-km grounding-line embayment on the Whales Deep Basin (WDB) middle continental shelf. Here, we reconstruct the pattern, duration and rate of retreat from a backstepping succession of small-scale grounding-zone ridges that formed on the embayment’s eastern flank. We used two end-member paleo-sediment fluxes, i.e., accumulation rates, to convert the cumulative sediment volumes of the ridge field to elapsed time for measured distances of grounding-line retreat. The end-members fluxes correspond to deposition rates for buttressed and unbuttressed ice stream flow. Both scenarios require sustained rapid retreat that exceeded several centuries. Grounding-line retreat is estimated to have averaged between ~ 100 ± 32 and ~ 700 ± 79 ma−1. The evidence favors the latter scenario because iceberg furrows that cross cut the ridges in deep water require weakly buttressed flow as the embayment opened. In comparison with the modern grounding-zone dynamics, this paleo-perspective provides confidence in model projections that a large-scale sustained contraction of grounded ice is underway in several Pacific-Ocean sectors of the WAIS.
Effects of application of horticultural soil amendments on decomposition, quantity, stabilisation and quality of soil carbon
Authors: Duddigan Sarah , Shaw Liz J. , Alexander Paul D. , Collins Chris D. 
Published: October 2022

AbstractApplication of organic soil amendments is commonplace in horticulture to improve soil fertility. Whether this practice can also augment the soil carbon (C) pool has been of increasing interest in recent years. We used a controlled field experiment that has received annual applications of six different horticultural soil amendments for seven consecutive years. Each amendment was examined in terms of its contribution to bulk C and the distribution of C between theoretical pools, as defined by physical fractionation. Physical fractionation was combined with 13C nuclear magnetic resonance spectroscopy with cross-polarization and magic angle spinning (CPMAS NMR) analysis. Results indicated that the difference in total C concentration between treatments resulted from an increase in unprotected, free, particulate organic matter (fOM), rather than an increase in soil organic matter being occluded in aggregates or in organo-mineral complexes, and that C persisted in the fOM fraction as a result of accumulation in the alkyl C region. Unlike fresh litter or plant residues, organic amendments have undergone decomposition during the composting process (or during formation in the case of peat), in the absence of mineral soil components. This ex situ decomposition (and possible stabilization through acquired recalcitrance) could reduce the opportunity to become physically or chemically protected through association with the soil mineral phase following addition to soil. Carbon:Nitrogen (C:N) of amendment material likely influenced the rate of amendment decomposition. In addition, C:N determines the decomposition of plant litter inputs, as determined by the tea bag index.
Gadolinium-doped fluorescent carbon quantum dots as MRI contrast agents and fluorescent probes
Authors: Molaei Mohammad Jafar 
Published: October 2022

AbstractIn this research passivated gadolinium-doped carbon quantum dots (Gd-doped CQDs) were synthesized from starch by a hydrothermal method. The X-ray diffraction (XRD) pattern of the Gd-doped CQDs showed the formation of highly amorphous carbon. The Fourier transform infrared spectroscopy (FTIR) results suggested that the CQDs are functionalized with C-N and N–H bonds. The synthesized CQDs with a size distribution of 2–8 nm have an absorption peak at 271 nm in UV–Visible spectroscopy (UV–Vis). The photoluminescence (PL) in CQDs was dependent on the excitation wavelength. The QY of the synthesized CQDs was calculated to be 13.2%. The Gd-doped CQDs exhibited sustained PL in ionic solutions with different ionic strengths and different temperatures up to 65 °C. Fluorescence imaging on mouse C34/connective tissue-L929 cells confirmed that Gd-doped CQDs could be well distributed over the cytoplasm. The magnetic resonance imaging (MRI) showed that the Gd-doped CQDs have extremely high longitudinal and transverse relaxivity values of as high as 218.28 mM−1 s−1 and 364.68 mM−1 s−1. The synthesized Gd-doped CQDs are promising candidates as multifunctional imaging probes and MRI contrast agents in biomedical diagnosis and brain mapping applications.
Effects of water extracts of Flaveria bidentis on the seed germination and seedling growth of three plants
Authors: Dai Lei , Wu Lili , Zhou Xiuren , Jian Zaiyou , Meng Li , Xu Guifang 
Published: October 2022

AbstractTo further explore the mechanism behind the allelopathic effects of Flaveria bidentis, we investigated the allelopathic effects of water extracts from Flaveria bidentis leaves on three plants, Shanghai green, barnyard grass and wheat. The results showed that the water extracts inhibited the germination potential, germination rate, seedling height, root length, chlorophyll content, fresh weight and dry weight of the three plants, and increasing the extract concentration further increased the inhibitory effect. The allelopathic effects of the water extracts from Flaveria bidentis leaves on the three receptor plants differed in strength from strong to weak as follows: Shanghai green > barnyard grass > wheat. Thus, wheat had strong resistance to the allelopathic effects of Flaveria bidentis and could be planted in area where Flaveria bidentis occurs. The effect of the water extract from Flaveria bidentis leaves on the seed germination and seedling growth of barnyard grass was obvious; thus, this extract could be used for the biological control of barnyard grass.
SPINA Carb: a simple mathematical model supporting fast in-vivo estimation of insulin sensitivity and beta cell function
Authors: Dietrich Johannes W. , Dasgupta Riddhi , Anoop Shajith , Jebasingh Felix , Kurian Mathews E. , Inbakumari Mercy , Boehm Bernhard O. , Thomas Nihal 
Published: October 2022

AbstractModelling insulin-glucose homeostasis may provide novel functional insights. In particular, simple models are clinically useful if they yield diagnostic methods. Examples include the homeostasis model assessment (HOMA) and the quantitative insulin sensitivity check index (QUICKI). However, limitations of these approaches have been criticised. Moreover, recent advances in physiological and biochemical research prompt further refinement in this area. We have developed a nonlinear model based on fundamental physiological motifs, including saturation kinetics, non-competitive inhibition, and pharmacokinetics. This model explains the evolution of insulin and glucose concentrations from perturbation to steady-state. Additionally, it lays the foundation of a structure parameter inference approach (SPINA), providing novel biomarkers of carbohydrate homeostasis, namely the secretory capacity of beta-cells (SPINA-GBeta) and insulin receptor gain (SPINA-GR). These markers correlate with central parameters of glucose metabolism, including average glucose infusion rate in hyperinsulinemic glucose clamp studies, response to oral glucose tolerance testing and HbA1c. Moreover, they mirror multiple measures of body composition. Compared to normal controls, SPINA-GR is significantly reduced in subjects with diabetes and prediabetes. The new model explains important physiological phenomena of insulin-glucose homeostasis. Clinical validation suggests that it may provide an efficient biomarker panel for screening purposes and clinical research.
MRBSChain a novel scalable medical records binance smart chain framework enabling a paradigm shift in medical records management
Authors: Monga Suhasini , Singh Dilbag 
Published: October 2022

AbstractMedical records management had always been a challenging in healthcare sector. Traditionally, medical records are handled either manually or electronically that are under the stewardship of hospitals/healthcare institutions. A patient centric approach is the new paradigm where patient is an inherent part of the healthcare ecosystem controlling the access and sharing of his/her personal medical care information. Medical care information requires robust security and privacy. Also there are other issues like confidentiality, interoperability, scalability, cost efficiency and timeliness that need to be addressed. To achieve these objectives, this paper proposes a novel-scalable patient centric yet privacy preserving framework for efficient and secure electronic medical records management. In addition, proposed system generates a unified trusted record and authentication role mapping for enforcing secure access control for medical records using complex encryption algorithms. This paper identifies 13 key performance factors for performance comparison of proposed framework with traditional models. Ethereum and Binance Smart Chain acted as a benchmark platform for performance evaluation of MRBSChain on the basis of three metrics (transaction cost, average block time and deployment cost).At last, a comparative analysis of MRBSChain with other state of art blockchain systems on the basis of execution time is presented in the paper.
Urine stabilization and normalization strategies favor unbiased analysis of urinary EV content
Authors: Vago Riccardo , Radano Giorgia , Zocco Davide , Zarovni Natasa 
Published: October 2022

AbstractUrine features an ideal source of non-invasive diagnostic markers. Some intrinsic and methodological issues still pose barriers to its full potential as liquid biopsy substrate. Unlike blood, urine concentration varies with nutrition, hydration and environmental factors. Urine is enriched with EVs from urinary-genital tract, while its conservation, purification and normalization can introduce bias in analysis of EV subsets in inter-and intra-individual comparisons. The present study evaluated the methods that decrease such biases such as appropriate and feasible urine storage, optimal single-step EV purification method for recovery of proteins and RNAs from small urine volumes and a normalization method for quantitative analysis of urine EV RNAs. Ultracentrifugation, chemical precipitation and immuno-affinity were used to isolate EVs from healthy donors’ urine that was stored frozen or at room temperature for up to 6 months. Multiple urine biochemical and EV parameters, including particle count and protein content, were compared across urine samples. To this purpose nanoparticle tracking analysis (NTA) and protein assessment by BCA, ELISA and WB assays were performed. These measurements were correlated with relative abundances of selected EV mRNAs and miRNAs assessed by RT-PCR and ranked for the ability to reflect and correct for EV content variations in longitudinal urine samples. All purification methods enabled recovery and downstream analysis of EVs from as few as 1 ml of urine. Our findings highlight long term stability of EV RNAs upon urine storage at RT as well as excellent correlation of EV content in urine with some routinely measured biochemical features, such as total urine protein and albumin, but not creatinine most conventionally used for urine normalization. Comparative evaluation of mRNA and miRNAs in EV isolates revealed specific RNAs, in particular RNY4 and small miRNA panel, levels of which well reflected the inter-sample EV variation and therefore useful as possible post-analytical normalizers of EV RNA content. We describe some realistic urine processing and normalization solutions for unbiased readout of EV biomarker studies and routine clinical sampling and diagnostics providing the input for design of larger validation studies employing urine EVs as biomarkers for particular conditions and diseases.
Resting-state heart rate variability (HRV) mediates the association between perceived chronic stress and ambiguity avoidance
Authors: Jiryis Talita , Magal Noa , Fructher Eyal , Hertz Uri , Admon Roee 
Published: October 2022

AbstractChronic stress is associated with profound behavioral and physiological alterations, including intolerance to uncertainty and reduced resting-state heart-rate-variability (HRV). Critically, uncertainty may arise in situations with known probabilities (risk) or unknown probabilities (ambiguity). Whether associations between chronic stress and decision-making under uncertainty are dependent on the specific type of uncertain decisions, and whether physiological alterations play a role in these putative associations is not yet clear. Here, ninety-two healthy adults that exhibit various levels of perceived chronic stress underwent resting-state HRV recording before completing a behavioral task that involves decision-making under either risk or ambiguity. Computational modelling quantified participants’ behavioral attitudes of approach and avoidance separately for risk and ambiguity. Results indicate, as expected, that perceived chronic stress is positively associated with intolerance to uncertainty and negatively associated with resting-state HRV. Contrary to expectations, behavioral attitudes towards risk and ambiguity were not directly associated with perceived chronic stress, yet HRV fully mediated the association between chronic stress and ambiguity avoidance. Taken together and given the direction of the associations, elevated HRV despite chronic stress may foster adaptive behavior in the form of avoiding ambiguous situations, and hence contribute to reduced exposure to uncertainty and to lower levels of allostatic load.
Bullet impacts in building stone excavate approximately conical craters, with dimensions that are controlled by target material
Authors: Campbell Oliver , Blenkinsop Tom , Gilbert Oscar , Mol Lisa 
Published: October 2022

AbstractBullet impacts are a ubiquitous form of damage to the built environment resulting from armed conflicts. Bullet impacts into stone buildings result in surficial cratering, fracturing, and changes to material properties, such as permeability and surface hardness. Controlled experiments into two different sedimentary stones were conducted to characterise surface damage and to investigate the relationship between the impact energy (a function of engagement distance) and crater volumes. Simplified geometries of crater volume using only depth and diameter measurements showed that the volume of a simple cone provides the best approximation (within 5%) to crater volume measured from photogrammetry models. This result suggests a quick and efficient method of estimating crater volumes during field assessments of damage. Impact energy has little consistent effect on crater volume over the engagement distances studied (100–400 m), but different target materials result in an order of magnitude variation in measured crater volumes. Bullet impacts in the experiments are similar in appearance to damage caused by hypervelocity experiments, but crater excavation is driven by momentum transfer to the target rather than a hemispherical shock wave. Therefore in contrast to predictions of impact scaling relationships for hypervelocity experiments, target material plays the dominant role in controlling damage, not projectile energy.
Genetic introgression between different groups reveals the differential process of Asian cultivated rice
Authors: Gong Hao , Han Bin 
Published: October 2022

AbstractThe Asian cultivated rice consists of two major subspecies: indica and japonica. There are already many reports about the existence of genetic introgression between the two subspecies. They propose some possible introgression-related genes from the comparison of population parameters. This study uses the genome-wide variation data of Asia cultivated rice to investigate their genetic introgression on the whole genome level. We detect a total of 13 significantly high introgression loci between the tropical japonica and indica populations. Two different methods are used to identify the genetic introgression regions. For most of the detected introgression regions, they generally get consistent results. Some previously known introgression genes are detected in the identified introgression loci, such as heat resistance gene TT1 and GLW7. The biological functions for these genetic introgression regions are annotated by the published QTL mapping results. We find that genetic introgression plays a vital role in the determination of both the phenotype and the domestication process of different groups. Our study also provides useful information and resources for the study of rice gene function and the domestication process.
Leaf tissue metabolomics fingerprinting of Citronella gongonha Mart. by 1H HR-MAS NMR
Authors: Ali Sher , Badshah Gul , Ali Umar , Siddique Afridi Muhammad , Shamim Anwar , Khan Ajmir , Luiz Felipe Soares Frederico , Rocha Alencar Menezes Leociley , Theodoro Rezende Vanessa , Barison Andersson , Fernandes de Oliveira Carlos Augusto , Gustavo Tonin Fernando 
Published: October 2022

AbstractThis research characterizes key metabolites in the leaf from Citronella gongonha Martius (Mart.) Howard (Cardiopteridaceae). All metabolites were assessed in intact leaf tissue by proton (1H) high-resolution magic angle spinning (HR-MAS) nuclear magnetic resonance (NMR) spectroscopy integrated with the principal component analysis (PCA) to depict molecular association with the seasonal change. The major ‘known unknown’ metabolites detected in 1H HR-MAS NMR were derivatives of flavonoid, polyphenolic and monoterpenoid compounds such as kaempferol-3-O-dihexoside, caffeoyl glucoside (2), 3-O-caffeoylquinic acid (3), 5-O-caffeoylquinic acid (4), kingiside (5), 8-epi-kingisidic acid (6), (7α)-7-O-methylmorroniside (7), (7β)-7-O-methylmorroniside (8) and alpigenoside (9) together with the universally occurring sucrose (10), α-glucoses (11, 12), alanine (13), and fatty (linolenic) acid (14). Several of the major metabolites (1, 2–9) were additionally confirmed by liquid chromatography tandem mass spectrometry (LC–MS/MS). In regard with the PCA results, metabolites 1, 2–9 and 14 were influenced by seasonal variation and/or from further (a) biotic environmental conditions. The findings in this work indicate that C. gongonha Mart. is an effective medicinal plant by preserving particularly compounds 2, 3–9 in abundant amounts. Because of close susceptibility with seasonal shift and ecological trends, further longitudinal studies are needed to realize the physiology and mechanism involved in the production of these and new metabolites in this plant under controlled conditions. Also, future studies are recommended to classify different epimers, especially of the phenolics and monoterpenoids in the given plant.