bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perceived Self-Efficacy, Confidence, and Skill Among Factors of Adult Patient Participation in Transitional Care: A Systematic Review of Quantitative Studies
Authors: Bailey Andrea , Mallow Jennifer , Theeke Laurie 
Published: January 2022

Introduction An advancing healthcare system in which patients are often required to self-manage care needs across countless settings and clinicians is increasing focus on participation in care. Mismanagement of care during already risky care-transitions further increases adverse care outcomes. Understanding factors of patient participation in transitional care in an adult population can help guide ways to reduce this burden. Methods A systematic review of the literature guided by the PRISMA method was conducted to identify factors of patient participation in transitional care. Quantitative studies in which patient participation was measured as an outcome variable and related statistics reported, and data were collected from an adult sample, were included. Two authors independently reviewed, critiqued, and synthesized the articles, and later categorized study variables according to identified trends. Results Twelve studies across international and multidisciplinary backgrounds were identified. Across studies, efforts were largely based on understanding or improving patient self-management of care during transitions. The majority of studies were experimental and care interventions grounded in patient and healthcare team partnerships, delivered beyond the hospital setting. An array of measures was used to quantify patient participation. Factors of patient participation in transitional care included higher perceived levels of self-efficacy, confidence, and skills to participate in care. Conclusion The results of this study suggest patient participation in transitional care is largely based on perceptions of self-efficacy, confidence, and skill. Patient-centric transitional care interventions targeting these factors and delivered beyond the hospital setting may improve care outcomes. Implications and direction for further studies includes conceptual clarity, the study of a broader-reaching patient population demographic, and use of multidisciplinary interventions. Outcome variables should remain focused on patient perception of care involvement and participation and expanded to include variables such as functional abilities and social determinants of health.
School leaders leading curriculum inclusion: Re-culturing pedagogy, re-imagining the student experience
Authors: Miller Paul , Lane James , Jaeggi Karen 
Published: January 2022

There has been widespread discussion within and outside educational institutions on the relevance and suitability of the curriculum provided to students in the United Kingdom. In North London, at the beginning of the school year 2019/2020, 11 primary school leaders, representing nine primary schools’ came together as a group, to begin to identify and examine ways they could improve their schools’ curriculum offer and ultimately the experience of students in their schools. The research produced four main findings. First, school leaders need targeted continuing professional development (CPD) to provide the knowledge and skills required to lead whole school change involving this level of complexity. Second, school leaders need well organised CPD. Third, school leaders learning should support an entire school community. Fourth, leaders can take charge of their own learning. That participants formed the group and contacted the consultancy for the training is an important point of note. That is, school leaders can (and do) take charge of their own learning for they know what they ‘lack’ or what they do not know, and they (have demonstrated they) possess the agency to seek out support.
The Wombat Hole Prospect, Benambra, Victoria, Australia: a Cu–Bi–(Te) exoskarn with unusual supergene mineralogy
Authors: Henry Dermot A. , Birch William D. 
Published: January 2022

AbstractThe Wombat Hole Prospect is a small copper–bismuth–(tellurium) exoskarn cropping out in the Morass Creek gorge, near Benambra, in eastern Victoria, Australia. Its main primary sulfide constituent is bornite in a grossular‒vesuvianite matrix. The skarn formed in a megaclast of Lower Silurian limestone from metal-bearing fluids accompanying the high-level emplacement of the Late Silurian–Lower Devonian Silver Flat Porphyry. Though the primary bornite mineralisation has been nearly obliterated by weathering, there are small relict patches containing exsolved grains of wittichenite (Cu3BiS3) and chalcopyrite, as well as inclusions of bismuth tellurides in the tetradymite group, namely sulphotsumoite (Bi3Te2S) and hedleyite (Bi7Te3). Joséite-A (Bi4TeS2), a mineral with a formula Bi3(Te,S)4, several unnamed Cu–Bi‒Te phases and minute grains of native bismuth have also been detected. Pervasive veining by chrysocolla throughout the garnet‒vesuvianite host contains a range of unusual secondary bismuth minerals that have crystallised at various times. These include mrázekite, namibite, pucherite, schumacherite and eulytine. Other secondary minerals present include wulfenite, bismutite, azurite, malachite and a poorly-crystalline bismuth oxide containing several weight percent tellurium. Rare grains of gold (electrum) containing up to 23 wt.% Ag are also present. The assemblage of grossular–vesuvianite with minor diopside is indicative of formation in a low-${\rm X}_{{\rm C}{\rm O}_ 2}$environment under fluid-buffered conditions. A temperature range between ~650°C and as low as ~150°C can be estimated from the exsolution of wittichenite and chalcopyrite from the bornite. The tetradymite-group inclusions formed first under low values of$f_{{\rm S}_ 2}$/$f_{{\rm T}{\rm e}_ 2}$, with bornite crystallising as values increased. The primary Cu‒Bi‒Te mineralogy and the unusual secondary mineral assemblage makes the Wombat Hole skarn unique in southeastern Australia. The deposit provides scope for studying the mobility of elements such as Bi and Te over short distances during weathering of hypogene ore minerals.
Disrupting the adult globin promoter alleviates promoter competition and reactivates fetal globin gene expression
Authors: Topfer Sarah K. , Feng Ruopeng , Huang Peng , Ly Lana C. , Martyn Gabriella E. , Blobel Gerd A. , Weiss Mitchell J. , Quinlan Kate G. R. , Crossley Merlin 
Published: January 2022

Abstract
The benign condition hereditary persistence of fetal hemoglobin (HPFH) is known to ameliorate symptoms of co-inherited β-hemoglobinopathies, such as sickle cell disease and β-thalassemia. The condition is sometimes associated with point mutations in the fetal globin promoters that disrupt the binding of the repressors BCL11A or ZBTB7A/LRF, which have been extensively studied. HPFH is also associated with a range of deletions within the β-globin locus that all reside downstream of the fetal HBG2 gene. These deletional forms of HPFH are poorly understood and are the focus of this study. Numerous different mechanisms have been proposed to explain how downstream deletions can boost the expression of the fetal globin genes, including the deletion of silencer elements, of genes encoding noncoding RNA, and bringing downstream enhancer elements into proximity with the fetal globin gene promoters. Here we systematically analyze the deletions associated with both HPFH and a related condition known as δβ-thalassemia and propose a unifying mechanism. In all cases where fetal globin is upregulated, the proximal adult β-globin (HBB) promoter is deleted. We use clustered regularly interspaced short palindromic repeats-mediated gene editing to delete or disrupt elements within the promoter and find that virtually all mutations that reduce ΗΒΒ promoter activity result in elevated fetal globin expression. These results fit with previous models where the fetal and adult globin genes compete for the distal locus control region and suggest that targeting the ΗΒΒ promoter might be explored to elevate fetal globin and reduce sickle globin expression as a treatment of β-hemoglobinopathies.
Underwater Laser Welding/Cladding for High-performance Repair of Marine Metal Materials: A Review
Authors: Sun Guifang , Wang Zhandong , Lu Yi , Chen Mingzhi , Yang Kun , Ni Zhonghua 
Published: January 2022

AbstractWith the rapid developments of marine resource exploitation, mounts of marine engineering equipment are settled on the ocean. When it is not possible to move the damaged equipment into a dry dock, welding operations must be performed in underwater environments. The underwater laser welding/cladding technique is a promising and advanced technique which could be widely applied to the maintenance of the damaged equipment. The present review paper aims to present a critical analysis and engineering overview of the underwater laser welding/cladding technique. First, we elaborated recent advances and key issues of drainage nozzles all over the world. Next, we presented the underwater laser processing and microstructural-mechanical behavior of repaired marine materials. Then, the newly developed powder-feeding based and wire-feeding based underwater laser direct metal deposition techniques were reviewed. The differences between the convection, conduction, and the metallurgical kinetics in the melt pools during underwater laser direct metal deposition and in-air laser direct metal deposition were illustrated. After that, several challenges that need to be overcame to achieve the full potential of the underwater laser welding/cladding technique are proposed. Finally, suggestions for future directions to aid the development of underwater laser welding/cladding technology and underwater metallurgical theory are provided. The present review will not only enrich the knowledge in the underwater repair technology, but also provide important guidance for the potential applications of the technology on the marine engineering.
Peripheral venous lactate levels substitute arterial lactate levels in the emergency department
Authors: Oi Yasufumi , Mori Kosuke , Yamagata Hidehiro , Nogaki Ayako , Takeda Tomoaki , Watanabe Chikara , Sakaguchi Yusuke , Ogawa Fumihiro , Abe Takeru , Imaki Shouhei , Takeuchi Ichiro 
Published: January 2022

Abstract
Background
Arterial lactate (AL) level is an important predictor of patient prognosis. AL and peripheral venous lactate (PVL) in blood gas analysis have a low concordance rate, and PVL cannot be used as a substitute for AL. However, if the AL range can be predicted from PVL, PVL may be an alternative method for predicting patient prognosis, and the risk of arterial puncture complications with AL may be reduced. This could be a safe and rapid test method.

Methods
This was a retrospective observational study of 125 cases in which blood gas analysis was performed on both arterial and venous blood with an infectious disease in an emergency department. Spearman’s rank correlation coefficient (r) and Bland–Altman analyses were performed. Sensitivity, specificity, and area under the curve (AUC) were calculated for PVL to predict AL < 2 mmol/L or < 4 mmol/L.

Results
The median [interquartile range] AL and PVL were 1.82 [1.25–2.46] vs. 2.08 [1.57–3.28], respectively, r was 0.93 (p < 0.0001), and a strong correlation was observed; however, Bland–Altman analysis showed disagreement. When AL < 2 mmol/L was used as the outcome, AUC was 0.970, the PVL cutoff value was 2.55 mmol/L, sensitivity was 85.71%, and specificity was 96.05%. If PVL < 2 mmol/L was the outcome, the sensitivity for AL < 2mmol/L was 100%, and for PVL levels ≥ 3 mmol/L, the specificity was 100%. When AL < 4 mmol/L was used as the outcome, AUC was 0.967, the PVL cutoff value was 3.4 mmol/L, sensitivity was 100%, and specificity was 85.84%. When PVL < 3.5 mmol/L was the outcome, the sensitivity for AL < 4 mmol/L was 100%, and for PVL levels ≥ 4 mmol/L, the specificity was 93.81%.

Conclusions
This study revealed that PVL and AL levels in the same critically ill patients did not perfectly agree with each other but were strongly correlated. Furthermore, the high accuracy for predicting AL ranges from PVL levels explains why PVL levels could be used as a substitute for AL level ranges.
Characteristics of emergency department admissions with congestive heart failure in the United States: a Nationwide cross-sectional study
Authors: Zhang Xingyu , Qiu Peilin , Prushinskaya Anna , Jiang Yun , Fan Hui , Yang Sheng 
Published: January 2022

Abstract
Background
To understand the characteristics and clinical presentation of patients with Congestive Heart Failure (CHF) visiting the emergency department (ED), and to examine the factors associated with clinical outcomes and medical resource utilization amongst the studied population.

Methods
We analyzed the 2014–2016 ED visit data collected by the National Hospital Ambulatory Medical Care Survey Emergency Department Subfile. We described patients’ characteristics and clinical outcomes after ED visits with CHF vs. without CHF. Logistic regression models were used to estimate the association between these characteristics and CHF.

Results
ED visits with CHF visits represented 3.9% of annual ED visits (3,647,113 out of 92,899,685). ED patients with CHF were mostly non-Hispanic White (69.9%). Compared with other ED patients, those with CHF were older, including 71.2% that were were older than 60. ED patients with CHF were more likely to be admitted to the hospital (aOR: 2.56; 95% CI: 2.28–2.87) and intensive care unit (ICU) (aOR: 2.19; 95% CI: 1.77–2.71).

Conclusions
This study describes the demographic, socioeconic, and clinical characteristics of patients who present to the ED with CHF through analysis of a comprehensive national survey. These patients require a higher level of emergency care due to their higher chance of admittance to the hospital and ICU.
Postoperative survival effect of the number of examined lymph nodes on esophageal squamous cell carcinoma with pathological stage T1–3N0M0
Authors: Wu Lei-Lei , Zhong Jiu-Di , Zhu Jia-Li , Kang Lu , Huang Yang-Yu , Lin Peng , Long Hao , Zhang Lan-Jun , Ma Qi-Long , Qiu Li-Hong , Ma Guo-Wei 
Published: January 2022

Abstract
Background
The postoperative survival effect of the number of examined lymph nodes on patients of R0-resected esophageal squamous cell carcinoma with pathological stage T1–3N0M0 is still unclear.

Methods
Patients diagnosed with pathological stage T1–3N0M0 esophageal squamous cell carcinoma from two cancer databases—our cancer center (N = 707), and Surveillance Epidemiology and End Results (N = 151). The primary clinical endpoint was overall survival. The X-tile software was used to determine the optimal cutoff value of the number of examined lymph nodes, and propensity score matching was conducted to reduce selection bias according to the results of X-tile software. The cohort of 151 patients from another database was used for validation.

Results
X-tile software provided an optimal cutoff value of 15 examined lymph nodes based on 707 patients, and 231 pairs of matched patients were included. In the unmatched cohort, Cox proportional hazard regression analysis revealed better overall survival in patients with more than 15 examined lymph nodes (adjusted hazard ratio, 0.566, 95% confidence interval, 0.445–0.720; p < 0.001) compared with patients with 15 or fewer examined lymph nodes. In the validation cohort, patients with more than 15 examined lymph nodes also had better overall survival (adjusted hazard ratio 0.665, p = 0.047).

Conclusions
The number of examined lymph nodes is a significant prognostic factor in esophageal squamous cell carcinoma patients with pathological stage T1–3N0M0, and more than 15 examined lymph nodes are associated with better overall survival. Although the difference is not significant, the survival curve of patients with examined lymph nodes > 30 is better than those with examined lymph nodes 15–30. We believe that the number of examined lymph nodes can provide prognostic guidance for those patients, and the more examined lymph nodes cause lesser occult lymph nodes metastasis and lead to a better prognosis. Therefore, surgeons and pathologists should try to examine as many lymph nodes as possible to evaluate the pathological stage precisely. However, we need more validation from other studies.
Prevalence and predictors of depression among emergency physicians: a national cross-sectional study
Authors: Chen Yueming , Shen Xin , Feng Jing , Lei Zihui , Zhang Weixin , Song Xingyue , Lv Chuanzhu 
Published: January 2022

Abstract
Background
Physicians' depression can damage their physical and mental health and can also lead to prescribing errors and reduced quality of health care. Emergency physicians are a potentially high-risk community, but there have been no large-sample studies on the prevalence and predictors of depression among this population.

Methods
A nationally representative cross-sectional survey of 15,243 emergency physicians was conducted in 31 provinces across China between July and September 2019. Multivariable logistic regression analysis was performed to identify predictors of depression.

Results
A total of 35.59% of emergency physicians suffered from depression. Emergency physicians who were male (OR=0.91) and older [>37 and ≤43 (OR=0.83) or >43 (OR=0.71)], had high (OR=0.63) or middle (OR=0.70) level income, and participated in physical inactivity (OR=0.85) were not more likely to suffer depression. Meanwhile, those who were unmarried (OR=1.13) and smokers (OR=1.12) had higher education levels [Bachelor’s degree (OR=1.57) or Master’s degree or higher (OR=1.82)], long work tenure [>6 and ≤11 (OR=1.15) or >11;11 (OR=1.19)], poorer health status [fair (OR=1.67) or poor (OR=3.79)] and sleep quality [fair (OR=2.23) or poor (OR=4.94)], a history of hypertension (OR=1.13) and coronary heart disease (OR=1.57) and experienced shift work (OR=1.91) and violence (OR=4.94)].

Conclusion
Nearly one third of emergency physicians in China suffered from depression. Targeted measures should be taken to reduce the prevalence of depression to avoid a decline in health care quality and adversely impact the supply of emergency medical services.
Rationale and study protocol for a randomized controlled trial to determine the effectiveness of a culturally relevant, stress management enhanced behavioral weight loss intervention on weight loss outcomes of black women
Authors: Buro Acadia W. , Baskin Monica , Miller Darci , Ward Tayler , West Delia Smith , Gore L. Robert , Gwede Clement K. , Epel Elissa , Carson Tiffany L. 
Published: January 2022

Abstract
Background
Obesity is a persistent public health concern and a risk factor for many chronic diseases including at least 13 different cancers. Adult Black females have the highest prevalence of obesity (57%) compared to other racial/gender groups in the U.S. Although behavioral weight loss (BWL) interventions have demonstrated effectiveness, Black females tend to lose less weight than White counterparts. The higher prevalence of chronic psychological stress reported by Black females may contribute to their disproportionate prevalence of obesity and observed suboptimal weight loss. This study will examine the effectiveness of a 12-month culturally-targeted, stress management-enhanced BWL intervention on weight loss and stress reduction among Black females in a fully-powered randomized, controlled trial.

Methods
Adult Black females with obesity (n = 340) will be randomized to either a culturally targeted stress management-enhanced BWL intervention (BWL-Stress) or the same BWL intervention alone (BWL-alone). The primary outcome is weight change at month 6. Secondary outcomes will include changes in stress measures (e.g., perceived stress, cortisol), energy intake, and physical activity at month 6. We will also assess process measures (e.g., treatment adherence, treatment burden). Each outcome will also be evaluated at month 12 to assess longer-term effects of the intervention.

Discussion
This novel approach for enhancing an evidence-based BWL program with culturally-targeted stress management strategies for Black females addresses an understudied barrier to effective weight management among a population at high risk for obesity and obesity-related chronic diseases. This study will potentially elucidate psychological or behavioral mechanisms linking our novel intervention to study outcomes. If the intervention is proven to be effective, this study will have significant clinical and public health implications for weight management among Black females.

Trial registration
This study was registered on ClinicalTrials.gov, identifier NCT04335799t, on April 6, 2020.
The role of counselling in tuberculosis diagnostic evaluation and contact tracing: scoping review and stakeholder consultation of knowledge and research gaps
Authors: Foster Isabel , Sullivan Amanda , Makanda Goodman , Schoeman Ingrid , Tisile Phumeza , van der Westhuizen Helene-Mari , Theron Grant , Nathavitharana Ruvandhi R. 
Published: January 2022

Abstract
Background
Tuberculosis (TB) care cascade analyses show large gaps at early stages, including care-seeking and diagnostic evaluation, where promising interventions to decrease attrition are urgently needed. Person-centered care is prioritized in the World Health Organization’s End TB strategy; yet little is known about how it is delivered and can be optimized. Recommendations for counselling, a core component of person-centered care, are largely limited to its role in improving TB treatment adherence. The role of counselling to close key diagnostic gaps in the care cascade is poorly understood.

Methods
We conducted a scoping review to identify evidence on the use of counselling at TB diagnosis, for both people with presumptive TB and index patients to promote patient retention and contact tracing. Using search terms for TB, diagnosis and counselling, we systematically searched PubMed, EMBASE and Web of Science. Two independent reviewers screened all abstracts, full-texts, extracted data and conducted a quality assessment. We used thematic analysis to identify key themes.

Results
After screening 1785 articles, we extracted data from 15 studies and determined that the major themes best corresponded to the following gaps in the TB care cascade: care-seeking, pre-diagnosis, and pre-treatment. Studies were conducted across varied settings including pharmacies, primary health centres, and clinics, primarily in high TB incidence countries. No study directly evaluated the impact of counselling on outcomes such as treatment initiation or retention in care. Included studies suggested counselling may play an important role in improving the uptake of diagnostic testing and contact tracing. Barriers to counselling included time and personnel requirements. Stakeholder consultation emphasized the importance of high-quality counselling as a core tenet of TB care.

Conclusion
Data on the impact of counselling to improve TB case detection are absent from the literature. The shift towards person-centred care for TB presents an opportunity to incorporate counselling during earlier stages of the TB care cascade; however, evidence-based approaches are needed. Implementation research is needed to operationalize and evaluate counselling to strengthen high-quality TB care delivery.