Abstract PO-272: Factors associated with HPV vaccine uptake: Insights from those who receive the flu shot
Authors: Ratnasamy Philip P , Chagpar Anees 
Published: January 2022

Abstract
Introduction: While vaccine hesitancy is well-known, it remains unclear what factors influence individuals to obtain some vaccinations but not others. In the US, influenza vaccination rates are much higher than HPV vaccination rates. We sought to determine, among individuals who receive the influenza vaccine, factors that influence the uptake of HPV vaccination. Methods: The National Health Interview Survey (NHIS) is the largest source of health information for Americans and is designed to represent the entire civilian non-institutionalized US population. We utilized the 2018 NHIS to determine the proportion of the population who received HPV vaccination, influenza vaccination, or both. Further, amongst those who took the flu shot (and therefore were not vaccine-hesitant), we evaluated factors that influenced HPV vaccination. Results: There were 16,958 people, representing 184,361,526 in the population, between the ages of 18-64 who responded to questions as to whether they had ever received the HPV vaccine and whether they had received the influenza vaccine within the past year. 54.79% of these individuals had received neither vaccine, 32.42% received the flu shot but not HPV vaccination, and 5.76% received both vaccinations. Among those who received the flu shot in the past year, females (19.13% vs. 9.78% for males, p&lt;0.001), those who were married (36.61% vs. 9.43% for singles, p&lt;0.001), and those with high English proficiency (15.52% vs. 2.34% and 6.44% for those who spoke English “not well” and “not at all,” respectively, p&lt;0.001) were more likely to report having ever received an HPV vaccine. Race (p=0.029) and education level (p=0.002) also influenced HPV uptake in this population; family income relative to the federal poverty level was of borderline significance (p=0.0623). Region of residence in the US (p=0.116), health insurance status (p=0.127), and years living in the US (p=0.281) were not significant. On multivariate analysis, individuals who were female (OR: 2.78 vs. male; 95% CI: 2.25-3.43, p&lt;0.001), spoke English well (OR: 7.50 vs. not well; 95% CI: (2.45-22.96, p=0.002), and were married (OR: 6.61; 95% CI: 5.33-8.19, p&lt;0.001) were more likely to get the HPV vaccination; education and income relative to poverty were not significant in the model. In addition, after controlling for other factors, Black individuals (OR: 0.72; 95% CI: 0.52-0.98) and those who identified as “Other” race (OR: 0.36; 95% CI: 0.15-0.88) were less likely to get the HPV vaccination compared to Whites (p=0.010). Conclusions: Over 50% of individuals in the US report never receiving the HPV vaccine and not receiving the flu shot within the past year. Only 15% of the nearly 40% of individuals who had taken a flu shot within the past year also reported having received the HPV vaccine. People who are male, single, with low English proficiency, and/or who identify as Black or Other race may be a group of non-vaccine hesitant individuals who may be amenable to taking the HPV vaccine if appropriately targeted for the same.
Citation Format: Philip P Ratnasamy, Anees Chagpar. Factors associated with HPV vaccine uptake: Insights from those who receive the flu shot [abstract]. In: Proceedings of the AACR Virtual Conference: 14th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2021 Oct 6-8. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2022;31(1 Suppl):Abstract nr PO-272.