bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and validation of a prediction model for online gambling problems based on players' account data
Authors: Perrot Bastien , Hardouin Jean-Benoit , Thiabaud Elsa , Saillard Anaïs , Grall-Bronnec Marie , Challet-Bouju Gaëlle 
Published: September 2022

Abstract

Background and aims
Gambling disorder is characterized by problematic gambling behavior that causes significant problems and distress. This study aimed to develop and validate a predictive model for screening online problem gamblers based on players' account data.

Methods
Two random samples of French online gamblers in skill-based (poker, horse race betting and sports betting, n = 8,172) and pure chance games (scratch games and lotteries, n = 5,404) answered an online survey and gambling tracking data were retrospectively collected for the participants. The survey included age and gender, gambling habits, and the Problem Gambling Severity Index (PGSI). We used machine learning algorithms to predict the PGSI categories with gambling tracking data. We internally validated the prediction models in a leave-out sample.

Results
When predicting gambling problems binary based on each PGSI threshold (1 for low-risk gambling, 5 for moderate-risk gambling and 8 for problem gambling), the predictive performances were good for the model for skill-based games (AUROCs from 0.72 to 0.82), but moderate for the model for pure chance games (AUROCs from 0.63 to 0.76, with wide confidence intervals) due to the lower frequency of problem gambling in this sample. When predicting the four PGSI categories altogether, performances were good for identifying extreme categories (non-problem and problem gamblers) but poorer for intermediate categories (low-risk and moderate-risk gamblers), whatever the type of game.

Conclusions
We developed an algorithm for screening online problem gamblers, excluding online casino gamblers, that could enable the setting of prevention measures for the most vulnerable gamblers.
Review of Liriomyza huidobrensis (Diptera: Agromyzidae) on potatoes in South Africa, with special reference to biological control using entomopathogens and parasitoids
Authors: Mugala Thabu , Visser Diedrich , Mugala Antoinette Paula Malan , Addison Pia 
Published: September 2022

Although agriculture is crucial to economic growth in South Africa, the industry faces several challenges, including the effects of pests and diseases that contribute to crop loss. Such losses severely affect the maintenance of food security. Therefore, a major challenge is finding effective, environmental-friendly control measures for insect pests. Potatoes are among the four most widely consumed vegetable crops worldwide. However, a potato crop can be infested by various pests, like the devastating leaf miner, Liriomyza huidobrensis (Blanchard) (Diptera: Agromyzidae). The leaf miner species has, since the early 2000s, become an important pest of various vegetable crops in South Africa. The species is highly invasive, causing up to 70 % damage of solanaceous crops. The damage that is caused by the leaf miner is direct, resulting from the female flies feeding on the leaf mesophyll during oviposition, and the larvae mining the leaves. Indirect damage is induced through pathogens entering through perforations that act as vectors of plant diseases. Biocontrol agents, e.g. entomopathogenic nematodes (EPNs), entomopathogenic fungi (EPF), and parasitoids have shown potential against L. huidobrensis. This review investigates the biology and morphological identification of L. huidobrensis, its host range in the Western Cape, and the potential of associated biocontrol agents, like EPNs, EPF and parasitoids, as future control options.
Use of urinary cotinine and cotinine/creatinine ratio as a biomarker of environmental tobacco exposure
Authors: ÖKSÜZ Ahmet , KUTLU Ruhuşen , REİSLİ İsmail , KILINC İbrahim 
Published: September 2022

Purpose: Exposure to Environmental Tobacco Smoke (ETS) remains a worldwide public health problem. The purpose of this study was to investigate the relationship between parents' smoking habits at home and children's exposure to environmental tobacco smoke by measuring urinary cotinine levels and urine cotinine/creatinine ratios in children.
Materials and Methods: This case-control typed analytical study was conducted with 357 children in the 0-18 age group. The case group consisted of 180 children exposed to environmental cigarette smoke. As the control group, it consisted of 177 healthy children and non-smoking in their family. The levels of cotinine and creatinine in spot urinary were analyzed in both groups.
Results: The urinary cotinine level of the children was found to be statistically higher in those whose parents were smokers, female gender, fathers with a low educational level, and those with 3 or fewer rooms in the house. The urinary cotinine/creatinine ratio of the children was found to be statistically higher in those whose parents were smokers (15.91 pg/mg (1.54-147.54) vs 7.90 pg/mg (1.29-68.52)), female gender (13.19 pg/mg (1.79-115.07) vs 10.45 pg/mg (1.29-147.54)). Urinary cotinine levels in the ETS exposed group were affected 1042 times more than in the ETS unexposed group [OR:1042,462, 95% CI (139.821.839-7772.246)].
Conclusion: In the present study, urinary cotinine levels were found to be higher in children exposed to tobacco smoke than in children not exposed to tobacco smoke. In the light of these results, urinary cotinine can be used as a biomarker to evaluate exposure to ETS in children. Educating parents is essential to raising their awareness of exposure to ETS and teaching the right behaviors to protect children's health, especially in the home environment.
Optimization of perioperative hemodynamics in cytoreductive surgery of ovarian cancer with malignant ascites
Authors: YILDIZ Güneş Özlem , SERTCAKACİLAR Gokhan , AKYOL Duygu , KARAKAŞ Sema , HERGÜNSEL Gülsüm Oya 
Published: September 2022

Purpose: In this study, we aimed to evaluate the effects of norepinephrine and albumin use in patients with epithelial ovarian cancer with malignant ascite in order to maintain plasma oncotic pressure and intravascular volume, to provide perioperative hemodynamic stabilization and tissue perfusion. In addition, it was aimed to compare in terms of postoperative intensive care admission, hospital stay and complications.
Materials and Methods: A total of 66 patients, 38 with ascites and 28 without ascites, who underwent cytoreductive surgery for ovarian cancer were included in this study. PVI and invasive arterial monitoring of the patients were performed after hemodynamic stabilization (after the start of surgery) (T0). T0, 1st hour (T1) and 2nd hour (T2) and postoperative (Tpostop.) Ascites patients were composed of 3 subgroups which the ones received norepinephrine (NE) infusion, norepinephrine + albumin (NEA) infusion or only fluid therapy (FT). From the perioperative hemodynamic and laboratory data of the patients, tissue perfusion was evaluated with lactate, and hemodynamic status was evaluated with pleth variability index (PVI), perfusion index (PI) and mean arterial pressure (MAP).
Results: Demographic and clinical findings did not differ significantly between patients with and without ascites. Lactate level in NEA / NE group in Tpostop, PVI level in T1h, T2h and Tpostop time frames were determined higher than the FT group. PI was found to be significantly lower in the T2 time frame. The postoperative ICU admission rate was higher in the NEA and NE groups. The duration of ICU stay in group NEA was shorter than in group NE.
Conclusion: We recommend the use of low-dose NE with albumin to provide perioperative hemodynamic optimization, tissue perfusion and plasma oncotic pressure in surgery of ovarian cancer with malignant ascites. Despite high fluid replacement in these patients, the use of norepinephrine and albumin together may have an important role in preventing / reducing major complications in the perioperative period.
Relationship between serum neuron specific enolase levels and brain injury in patients with hyponatremia
Authors: MATYAR Selçuk , AÇIKALIN Ayça , DİŞEL Rana , GORUROGLU OZTURK Ozlem , DAĞLIOĞLU Gülçin , AKPINAR Onur 
Published: September 2022

Purpose: In this study, we aimed to investigate the effects of serum neuron specific enolase on the prediction of central nervous system injury and the clinical course in patients to have hyponatremia.
Materials and Methods: 75 adult patients with serum sodium levels less than 135 mEq/L were evaluated. The patients were grouped according to serum neuron specific enolase levels (group 1 ≤ 17.0 ng/mL and group 2 > 17.0 ng/mL). The groups were compared according to demographic and laboratory data.
Results: The incidence of hypertension, heart failure, and loss of consciousness was significantly higher in group 2 patient. High neuron specific enolase levels were related to lower serum sodium levels. The mean sodium levels were 129.5 ± 4.3 mEq/L and 126 ± 4.5 mEq/L in groups 1 and 2, respectively. Of the patients in group 2 (n = 45), 8 patients with loss of consciousness (low Glasgow Coma Scale scores) (i.e.
Cumulative sum analysis of the learning curve for laparoscopic complete mesocolic excision with central vascular ligation for right sided colon cancer
Authors: KOÇ Mehmet Ali 
Published: September 2022

Purpose: Every procedure, no matter how difficult, has a learning curve. However, no one discusses the learning curve for simple operations. This idea constantly comes up when there is a demanding surgical method that challenges habits. The aim of this study is to use cumulative sum analysis to estimate the learning curve of the demanding laparoscopic complete mesocolic excision+central vascular ligation technique for right sided colon cancer.
Materials and Methods: This retrospective study involved patients older than 18 years and with right-sided colon cancer admitted to Ankara University School of Medicine, Department of General Surgery between January 2015 and June 2022. The cumulative sum (CUSUM) chart based on operation duration and quantity of lymph nodes harvested was utilized to determine the learning curve.
Results: 53 patients included in this study. CUSUM analysis based on operation duration showed that Surgeon had passed the learning phase and was considered proficient after 21 cases. And the CUSUM analysis based on the lymph nodes harvested revealed that surgeon gained proficiency in 25th case. In terms of demographic, oncological, and operative data, there was no difference between the the groups defined by the phases according to the CUSUM analysis based on both operation duration and lymph node count.
Conclusion: Surgeons can become familiar with laparoscopic complete mesocolic excision for right sided colon cancer and perform it after approximately 21 to 25 operations.
The Use of Search Request Forms Can Identify Gaps in a Consumer Health Library Collection
Authors: Bridgeman Matthew 
Published: September 2022

A Review of:
Giannopoulos, E., Snow, M., Manley, M., McEwan, K., Stechkevich, A., Giuliani, M. E., & Papadakos, J. (2021). Identifying gaps in consumer health library collections: A retrospective review. Journal of the Medical Library Association: JMLA, 109(4), 656–666. https://doi.org/10.5195/jmla.2021.895
Abstract
Objective – The objective of this study was to determine if search request forms, which are used when a patron’s request for information cannot be fulfilled at the time of contact with the library team, can be used to identify gaps in consumer health library collections while offering some explanation for the gaps.
Design – Retrospective case study of search request forms.
Setting – A consumer health library at an academic cancer center in Canada.
Subjects – Library patrons: Patients, Patient family, other members of the center, and unspecified.
Methods – The researchers reviewed 260 search request forms submitted between 2013 and 2020. Of those, 249 records met inclusion criteria and were analyzed and coded. Coding included patron type, cancer diagnosis, information delivery, and content themes. This information was then used to identify gaps in the library collection and the reasons for the gaps.
Main Results – Patients were the primary patrons, asking 62.9% of the questions, followed by family members at 22.5%. The most common cancer type researched was breast at 23.3%, then hematology at 16.5%. gynecology, gastrointestinal, genitourinary, and sarcoma were next between 10% and 8.4%. The remaining cancer types ranged between 6.0 % and 2.0%, with brain being the lowest. Of the questions asked, 60% revealed a gap in the collection. The gaps included rare cancer diagnosis, treatment options, and prognosis. There were data collected on why the information was unavailable. While 53% of the gaps were a result of limited health consumer information, 25% were a result of paywall restrictions or content restricted to members.
Conclusion – Search request forms can be an effective tool in evaluating gaps in collections. In this study, the researchers were able to identify that breast cancer patients made up the most significant proportion of patrons, and the biggest gaps in the collection were related to their treatment decisions. One opportunity to bridge this gap is through collaboration with clinical teams in developing patient friendly resources on this topic. In addition, inter-institutional collaboration between libraries may also help. Continued review of forms can help inform collection decisions to better meet the needs of patrons.
KEPRIBADIAN, GAYA HIDUP, DAN KOMPENSASI SEBAGAI DETERMINAN KINERJA KARYAWAN
Authors: Liana Yuyuk , Adenia Firliany Ahlia , Djuharni Darti , Sugiono Djoko 
Published: September 2022

Research conducted on a coffee shop in Malang is intended to examine and analyze the influence of personality, lifestyle, and compensation on employee performance. Data were collected through questionnaires which were distributed to 59 respondents that consisted of managers and employees. Data were analyzed using multiple linear regression using SPSS. The results of this study indicate that personality has no significant effect on employee performance, lifestyle has a negative effect on employee performance, and compensation has a positive effect on employee performance. According to the partial test of each variable, compensation has the highest significant effect on employee performance since compensation is the primary motivation for employees to work to support their daily needs.
Keywords: compensation, life style, performance, personality
THE ADOPTION OF MOBILE PAYMENT LINKAJA IN INDONESIA
Authors: Widayani Anna , Rachmawati Ika , Normawati Rani Arifah , Latifah Nunuk 
Published: September 2022

Mobile payment is one of the alternative innovative payment methods that trigger the payment revolution in Indonesia. LinkAja, as one of the mobile payments in Indonesia, still has low brand awareness compared to other mobile payments. This study aims to examine the adoption of LinkAja referring to the Unified Theory of Acceptance and Use of Technology (UTAUT) that analyse the effect of performance expectancy, effort expectancy, social influence, and facilitating conditions on behavioural intention and the effect of behavioural intention on actual use. The sample of this research was LinkAja users in East Java Province taken using a purposive sampling technique. The final sample consisted of 100 respondents collected through an online questionnaire. Data were analysed using SEM (Structural Equation Modeling) with SmartPLS software. The results showed that performance expectation, social influence, and facilitating conditions had a significant effect on behavioural intention, and behavioural intention had a significant effect on actual use. However, effort expectancy had no significant effect on behavioural intention.
Keywords: behavioral intention, mobile payment, PLS-SEM, UTAUT
Equilibrium, Kinetic, and Thermodynamic Study of Removing Methyl Orange Dye from Aqueous Solution Using Zizphus spina-christi Leaf Powder
Authors: Mohammed Fadya F. 
Published: September 2022

In this study, Zizphus spina-christi leaf powder was applied for the adsorption of methyl orange. The effect of different operating parameters on the Batch Process adsorption was investigated such as solution pH (2-12), effect of contact time (0-60 min.), initial dye concentration (2-20 mg/L), effect of adsorbent dosage (0-4.5 g) and effect of temperature (20-50ᵒC). The results show a maximum removal rate and adsorption capacity (%R= 23.146, qe = 2.778 mg/g) at pH = 2 and equilibrium was reached at 40 min. The pseudo- second-order kinetics were found to be best fit for the removal process (R2 = 0.997). Different isotherm models (Langmuir, Freundlich, Dubini-Radushkevich,Temkin) were applied in this study and the adsorption process was found to fit Dubinin-Radushkevich isotherm (R2 = 0.970). The thermodynamic parameters: ∆Gº, ∆Hº, ∆Sº were also invested, the results indicate the process to be exothermic (∆Hº = -100.933 kJ/mole), non-spontaneous, and more feasible at lower operating temperatures, with a decrease in the randomness at the solid-liquid interface (∆Sº = - 0.370 kJ/mole.K)
Unraveling Candidate Biomarkers and Involved Biomedical Phenomena in Colorectal Cancer by Systematic Proteomics Analysis and Experimental procedures
Authors: Jahromi Noosha Zia , Mandani Amin Mahmoudi , Kaji Nahid Sadeghi Moghadam , Teshnizi Hadis Abbasi , Fattahi Nasrin , Yousefi Maryam , Sazegar Hossein 
Published: September 2022

Abstract
Background: Colorectal cancer (CRC) is the third most common cancer worldwide. The pathogenic mechanisms of this disorder are still unclear. Long noncoding RNAs (lncRNAs) play critical roles in gene expression regulation. This study aimed to introduce two novel lncRNAs as biomarkers of CRC diagnosis and treatment.
Method: In the first step, we investigated the differentially expressed proteins (DEPs) in CRC by bioinformatic study and constructed a regulatory multi-layer network (DEPs-miRNAs-lncRNAs) using Cytoscape software. In the last step, tissues ware collected from thirty patients after informed consent. Then, we evaluated the expression of LINC00943 and SLC9A3-AS1 lncRNAs in the 30 tumor tissues and 30 adjacent non-tumor tissues of the CRC patients by qRT-PCR.
Result: According to the evaluation of the constructed multi-layer, SLC9A3-AS1, LINC00943, and miR-1301-3p were considered important nodes that the association of the SLC9A3-AS1 and LINC00943 with CRC had not been investigated until now. We demonstrated that the expression of SLC9A3-AS1 and LINC00943 was up-regulated in the tumor tissues compared to adjacent non-tumor tissues in the CRC patients.
Conclusion: Considering the constructed interacting map not only provides a deeper understanding of the underlying mechanisms like an immunological aspect of CRC, which placed a premium on other pathways but also indicated several hub central molecules involved in CRC pathogenesis. In addition, the increase in LINC00943 and SLC9A3-AS1 gene expression in tumor tissues compared to adjacent healthy tissues in each patient confirms bioinformatical predictions and the role of these two genes in colorectal cancer. According to the results obtained, the LINC00943 gene is suggested as a biomarker in colorectal cancer. In previous studies as well, expression changes of LINC00943 and SLC9A3-AS1 genes were reported in gastric cancer and nasopharyngeal carcinoma, respectively. MiR-1301-3p expression changes were reported in colorectal cancer too.
Factors influencing the quality of life of bedridden older adult patients in China: A 3-month prospective multi-center study
Authors: Cao Jing , Chen Yanjun , Zhang Xiaoming , Liu Ying , Zhu Chen , Li Zhen , Wu Xinjuan 
Published: September 2022

Abstract
Background
This study aimed to describe bedridden older adult patients’ short-term quality of life and analyze its influencing factors.
Methods
This was a multicenter study in China involving 8,994 patients admitted to 25 hospitals. Quality of life was assessed using the EuroQol five-dimensions (EQ-5D) scale 3 months after enrollment. Multiple linear regression was used to analyze the factors associated with the quality of life among bedridden older adult patients.
Results
A total of 8,994 patients completed the study, and the mean EQ-5D index score was 0.853 (range, -0.149 to 1). Multiple linear regression analysis revealed the six risk factors affecting the quality of life: advanced age, longer bedridden time, disturbance of consciousness, pressure ulcer, pulmonary infection, and urinary tract infection. One protective factor was a normal body mass index (BMI).
Conclusion
Paying attention to the problems is critical for improving quality of life in these bedridden older adult patients.
Reconstruction and Trend Analysis of Widespread Heat Days in the MENA Region between 1871 and 2012
Authors: Rezaei Mohammad , Aalijahan Mehdi , Lupo Anthony R , Zerafati Hadi 
Published: September 2022

Abstract
One of the greatest challenges facing the world today is global warming. Long-term analysis of spatiotemporal variations in widespread heat days (WHDs) is one approach to monitoring this phenomenon, rather than focusing on the temperature trend. The objective of this study was to reconstruct the temporal and spatial variation of WHDs in the Middle East and North Africa (MENA) using the long-term NOAA/CIRES/ DOE 20th Century Reanalysis (V2) (20CRv2) reanalysis data between 1871 and 2012. Based on a 90% probability of occurrence, the temperature threshold for detecting WHDs was defined to be different for each grid point. Then, most WHDs of each month (142 samples) were identified based on the connected component labeling method. The results showed that most WHDs for each month occurred mainly after 2000. In general, the western parts of Iran, Syria, southern Turkey, Saudi Arabia, Kuwait, Egypt, and northern Sudan had the highest density of WHDs. In the second period (1941 to 2012), the extent of WHDs increased compared to the first period (1871 to 1941). The spatial relationship between WHDs density in the first and second periods showed no statistical relationship, indicating that WHDs were completely different in the two periods. The results of this study contribute to a better understanding of the effects of global warming by using the relatively longest data sets. The comparison between the two periods shows that the WHDs in MENA have changed in extent (instead of variability).