bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patients with low activation level report limited possibilities to participate in cancer care
Authors: Westman Bodil , Bergkvist Karin , Karlsson Rosenblad Andreas , Sharp Lena , Bergenmar Mia 
Published: January 2022

AbstractBackgroundCancer care trajectories are often complex, with potent multimodality treatments and multiple interactions with health care providers. Communication and coordination are challenging and the patients' responsibilities to take on more active roles in their own care are increasing.ObjectiveThis study aimed to investigate associations between patient activation level and participation in cancer care, sociodemographic characteristics, clinical data, health‐related quality of life (HRQoL) and helpfulness of received information.MethodsIn this cross‐sectional population‐based study, patients completed questionnaires on patient activation, perceived participation, HRQoL, helpfulness of received information and sociodemographic characteristics. Responses to the patient activation measures (PAMs) were classified into four levels (higher levels indicating more activation). Data on age, sex and cancer diagnosis were collected from the Swedish Cancer Register.ResultsData from 682 patients were analysed. On comparing patients at PAM levels 1 and 4, the latter reported significantly higher possibilities to influence care decisions (46.6% vs. 20.8%) and to ask questions regarding treatment and care (93.4% vs. 68.4%). Patients at PAM level 4 reported wanting to influence decision‐making to a higher extent, compared with patients at other PAM levels, and reported clinically significantly higher HRQoL. No significant differences were found regarding sociodemographic characteristics.ConclusionWe found strong associations between perceived patient participation and activation levels, with limited possibility for participation among those with lower activation levels.Patient or Public ContributionDiscussions with patient representatives have raised the importance of participation. The preliminary findings were presented and discussed in a workshop with representatives from 21 cancer patient advocacy groups.
Critical incident technique helps determine how health library and information services influence clinical decision making and patient care: A literature review
Authors: Sadeghi Halimeh , Nowkarizi Mohsen , Tajafari Masoumeh 
Published: January 2022

AbstractBackgroundThe Critical incident technique (CIT) has been used for decades in the assessment of the impact of library and information services on patient care and clinical decision making.ObjectivesThe purpose of this article is to identify and review the studies that have used CIT approach to assess the impact of library and information services on patient care and clinical decision making.MethodsRelated articles were searched in the information resources of Web of Science, PubMed, Embase, Scopus, Google Scholar and LISTA. Results: From among 1346 articles obtained, 22 met the inclusion criteria. The analysis of the articles indicated that CIT has been used for various purposes such as assessing the information value, assessing the information resources and librarians in their clinical practice and decision making, examining information‐seeking behaviour and analysing cost‐ benefits.DiscussionCritical incident technique is a flexible approach for libraries and information services, based on individuals’ experiences of finding and using information to help resolve a perceived problem.ConclusionsThe studies identified in this review offer a variety of methods for using CIT that other libraries might consider for their own impact studies.
Nigrospora sphaerica causing leaf spot in a new host, Eclipta prostrata (False Daisy), in China
Authors: Qiu Chaodong , Liu Chen , Niu Taotao , Zhu Wenhui , Liu Zhenyu 
Published: January 2022

AbstractLeaf spot symptom was observed in false daisy [Eclipta prostrata (L.) L., syn. Eclipta alba (L.) Hassk.] in Dianjiang County, Chongqing, China, in August 2019. The isolated and purified fungus CQLC820 was confirmed as Nigrospora sphaerica based on cultural and morphological features and phylogram of combined sequences of gene fragments of the internal transcribed spacer (ITS) region of ribosomal DNA and beta‐tubulin. Pathogenicity test revealed that isolate CQLC820 caused leaf spot lesions on false daisy, identical to those occurred naturally in the field. N. sphaerica was re‐isolated from the lesions and identified through morphological and sequence analysis. The causal agent of leaf spot of false daisy was identified as N. sphaerica. This is the first time to identify false daisy as a new host of N. sphaerica not only in China, but also in the world. There is a potential concern that N. sphaerica might have a threat on production of false daisy, a traditional herbal medicine with a long history of uses for treating haemorrhagic diseases in Asia and South America.
Imaging features of retroperitoneal extra‐adrenal paragangliomas in 10 dogs
Authors: Gombert Alexis , Diana Alessia , Hecht Silke , Nicoli Stefano , Fracassi Federico , Mortier Jeremy , Reyes‐Gomez Edouard , Pey Pascaline 
Published: January 2022

AbstractRetroperitoneal paragangliomas are rare tumors of the neuroendocrine system. Only a few canine case reports are available with rare descriptions of their imaging features. The objectives of this multi‐center, retrospective case series study were to describe the diagnostic imaging features of confirmed retroperitoneal paragangliomas and specify their location. Medical records and imaging studies of 10 affected dogs with cytological or histopathologic results concordant with retroperitoneal paragangliomas were evaluated. Dogs had a median age of 9 years. Four of them had clinical signs and laboratory reports compatible with excessive production of catecholamines. Six ultrasound, four CT, four radiographic, and one MRI studies were included. The paragangliomas did not have a specific location along the aorta. They were of various sizes (median 33 mm, range: 9–85 mm of length). Masses had heterogeneous parenchyma in six of 10 dogs, regardless of the imaging modality. Strong contrast enhancement was found in all CT studies. Encircling of at least one vessel was detected in six of 10 masses, clear invasion of a vessel was identified in one of 10 masses. In five of 10 cases, the masses were initially misconstrued as lymph nodes by the on‐site radiologist. Retroperitoneal paragangliomas appear along the abdominal aorta, often presenting heterogeneous parenchyma, possibly affecting the local vasculature, and displaying strong contrast enhancement on CT. Clinical signs can be secondary to mass effects or excessive catecholamine production. Underdiagnosis and misdiagnosis of this tumor are suspected as they can be silent, of small size, or confused with other structures.
Modeling of Cube Array Roughness: RANS, Large Eddy Simulation, and Direct Numerical Simulation
Authors: Altland Samuel , Xu Haosen H. A. , Yang Xiang I. A. , Kunz Robert 
Published: January 2022

AbstractFlow over arrays of cubes is an extensively studied model problem for rough wall turbulent boundary layers. While considerable research has been performed in computationally investigating these topologies using direct numerical simulation (DNS) and large eddy simulation (LES), the ability of sublayer-resolved Reynolds-averaged Navier–Stokes (RANS) to predict the bulk flow phenomena of these systems is relatively unexplored, especially at low and high packing densities. Here, RANS simulations are conducted on six different packing densities of cubes in aligned and staggered configurations. The packing densities investigated span from what would classically be defined as isolated, up to those in the d-type roughness regime, filling in the gap in the present literature. Three different sublayer-resolved turbulence closure models were tested for each case: a low Reynolds number k–ϵ model, the Menter k–ω SST model, and a full Reynolds stress model. Comparisons of the velocity fields, secondary flow features, and drag coefficients are made between the RANS results and existing LES and DNS results. There is a significant degree of variability in the performance of the various RANS models across all comparison metrics. However, the Reynolds stress model demonstrated the best accuracy in terms of the mean velocity profile as well as drag partition across the range of packing densities.
Respiratory function monitoring to improve the outcomes following neonatal resuscitation: a systematic review and meta-analysis
Authors: de Medeiros Sarah Marie , Mangat Avneet , Polglase Graeme R , Sarrato G Zeballos , Davis Peter G , Schmölzer Georg M 
Published: January 2022

ImportanceAnimal and observational human studies report that delivery of excessive tidal volume (VT) at birth is associated with lung and brain injury. Using a respiratory function monitor (RFM) to guide VTdelivery might reduce injury and improve outcomes.ObjectiveTo determine whether use of an RFM in addition to clinical assessment versus clinical assessment alone during mask ventilation in the delivery room reduces in-hospital mortality and morbidity of infants <37 weeks’ gestation.Study selectionRandomised controlled trials (RCTs) comparing RFM in addition to clinical assessment versus clinical assessment alone during mask ventilation in the delivery room of infants born <37 weeks’ gestation.Data analysisRisk of bias was assessed using Covidence Collaboration tool and pooled into a meta-analysis using a random-effects model. The primary outcome was death prior to discharge.Main outcomeDeath before hospital discharge.ResultsThree RCTs enrolling 443 infants were combined in a meta-analysis. The pooled analysis showed no difference in rates of death before discharge with an RFM versus no RFM, relative risk (RR) 95% (CI) 0.98 (0.64 to 1.48). The pooled analysis suggested a significant reduction for brain injury (a combination of intraventricular haemorrhage and periventricular leucomalacia) (RR 0.65 (0.48 to 0.89), p=0.006) and for intraventricular haemorrhage (RR 0.69 (0.50 to 0.96), p=0.03) in infants receiving positive pressure ventilation with an RFM versus no RFM.ConclusionIn infants <37 weeks, an RFM in addition to clinical assessment compared with clinical assessment during mask ventilation resulted in similar in-hospital mortality, significant reduction for any brain injury and intraventricular haemorrhage. Further trials are required to determine whether RFMs should be routinely available for neonatal resuscitation.
Socioeconomic deprivation, age and language are barriers to accessing personal health records: a cross-sectional study of a large hospital-based personal health record system
Authors: Chapman Rachel , Haroon Shamil , Simms-Williams Nikita , Bhala Neeraj , Miah Foyzal , Nirantharakumar Krishnarajah , Ferguson James 
Published: January 2022

ObjectivesTo investigate barriers to accessing a hospital-based personal health record (PHR) system.DesignRetrospective cross-sectional study.SettingThis study was conducted in a large secondary and tertiary acute care trust in Birmingham, UK.ParticipantsData were collected from 28 637 patients who attended liver medicine, diabetes, renal medicine or endocrinology specialist outpatient clinics from 1 June 2017 to 31 May 2018.Primary and secondary outcome measuresThe primary outcome measure was sign up to and activation of the PHR. The secondary outcomes were the use of the PHR, defined as the number of logons and frequency of access of specific PHR functions.Results8070 patients (28.2%) were signed up to the PHR and 4286 patients (53.1% of those signed up) went on to activate their PHR account. Patients aged 75 years and older were significantly less likely to be signed up (adjusted OR, aOR 0.40, 95% CI 0.36 to 0.44) or to activate (aOR 0.39, 0.32 to 0.47) their PHR than patients aged 35–54. Patients who did not need an interpreter were more likely to be signed up (aOR 1.63, 95% CI 1.33 to 1.99) and to activate (aOR 3.16, 95% CI 1.96 to 5.09) their PHR. Patients living in the least deprived areas were more than twice as likely to be signed up (aOR 2.31, 95% CI 2.04 to 2.63), and were three times more likely to activate their PHR (aOR 2.99, 95% CI 2.40 to 3.71), than those in the most deprived.ConclusionSocioeconomic deprivation, older age and non-English language were significant barriers to accessing a hospital-based PHR. Strategies are needed to account for these factors to ensure that PHRs do not widen health inequalities.
Unbiased interpolated neutron-star EoS at finite T for modified gravity studies
Authors: Lope-Oter Eva , Llanes-Estrada Felipe J. 
Published: January 2022

AbstractNeutron stars and their mergers provide the highest-density regime in which Einstein’s equations in full (with a matter source) can be tested against modified theories of gravity. But doing so requires a priori knowledge of the Equation of State from nuclear and hadron physics, where no contamination from computations of astrophysics observables within General Relativity has been built in. We extend the nEoS uncertainty bands, useful for this very purpose, to finite (but small) temperatures up to $$T=30$$

T
=
30

MeV, given that the necessary computations in ChPT and in pQCD are already available in the literature. The T-dependent band boundaries will be provided through the COMPOSE repository and our own website.
Endothelial Intracellular ANG (Angiogenin) Protects Against Atherosclerosis by Decreasing Endoplasmic Reticulum Stress
Authors: Su Enyong , Yu Peng , Zhang Baoli , Zhang Anjing , Xie Shiyao , Zhang Chunyu , Li Su , Zou Yunzeng , Liu Ming , Jiang Hong , Ge Junbo 
Published: January 2022

Background:
ANG (angiogenin) is essential for cellular adaptation to endoplasmic reticulum (ER) stress, a process closely associated with cardiovascular diseases, including atherosclerosis. We aimed to investigate the role of ANG in the progression of atherosclerosis and elucidate its underlying molecular mechanisms.

Methods:
We constructed adenoassociated virus 9 ANG overexpression vectors and endothelial ANG- and ApoE (apolipoprotein E)-deficient mice to determine the effects of ANG on ER stress and atherosclerotic lesions. RNA sequencing of endothelial ANG- and ApoE-deficient mice identified ANG-dependent downregulation of ST3GAL5 (ST3 beta-galactoside alpha-2,3-sialyltransferase 5) expression, and the direct regulation of ST3GAL5 by ANG was verified by chromatin immunoprecipitation sequencing and luciferase reporter assay results.

Results:

Reanalysis of expression profiling datasets indicated decreased ANG levels in patients’ atherosclerotic lesions, and these data were validated in aortas from ApoE
−/−
mice. ER stress marker and adhesion molecule levels, aortic root lesions and macrophage deposition were substantially reduced in ApoE
−/−
mice injected with an adenoassociated virus 9 ANG without signal peptide (ANG-ΔSP) overexpression vector compared with empty and full-length ANG overexpression vectors. Endothelial ANG deficiency significantly elevated ER stress and increased adhesion molecule expression, which aggravated atherosclerotic lesions and enhanced THP-1 monocyte adhesion to endothelial cells in vivo and in vitro, respectively. Furthermore, ANG-ΔSP overexpression significantly attenuated oxidized low-density lipoprotein-induced ER stress and THP-1 monocyte adhesion to endothelial cells, which were reversed by ST3GAL5 inhibition.

Conclusions:
These results suggest that endothelial intracellular ANG is a novel therapeutic against atherosclerosis and exerts atheroprotective effects via ST3GAL5-mediated ER stress suppression.
One God, Two Powers, and the Rabbinic Rejection of Subordinationism
Authors: Grossberg David Michael 
Published: January 2022

Abstract
This article furthers our understanding of rabbinic theology through an examination of its characteristic modes of expression. I demonstrate that although the rabbinic literature frequently polemicizes against perceived deviant theologies, it refrains from explicit expressions of God’s unity. This disinclination derives from the target and intent of rabbinic theological polemic. The rabbis’ opponents were not Christian binitarians who believed in multiple divine persons, but what I will refer to as Jewish subordinationists who believed in created divine agents through which God acts in the world. The rabbis were therefore less concerned with the ontological nature of God’s unity than they were with distancing all other beings from God’s sole sovereignty. My work provides additional textual support for the growing scholarly consensus that Jewish proponents of Logos theologies were among the rabbis’ earliest opponents, but it challenges the current convention that interprets these theologies in a primarily Christian binitarian context.
3. Traditions and Limitations of Participatory Research
Authors: Martinez-Vargas Carmen 
Published: January 2022

This chapter explores the complexities of investigating participatory approaches as a research field. The chapter divides the field into four major research areas (industrial, development, Indigenous, and educational) in order to clarify the diverse foundational assumptions of different practices and their distinct theoretical grounds.
After the exploration of these branches, the major challenges for the field are summarised. The chapter investigates issues around individual/collective practices, the contested terms and application of participation in different practices, credibility and validity within the academic context, and the challenges arising from embracing diverse practices. This chapter focuses on the gaps between each of the four proposed branches and decoloniality, highlighting spaces where we might usefully introduce the Capabilities Approach as a theoretical frame. Thus, this chapter provides the starting point for a conceptualisation of participatory capabilities-based research, in order to resolve certain limitations of these four branches.
8. DCR for Socially Just Higher Education
Authors: Martinez-Vargas Carmen 
Published: January 2022

Chapter Eight focuses on the idea of justice and the challenges and lessons learned from the South African case study (Sen, 1999). It combines conceptual and empirical elements, prompting a conversation between the five DCR principles and elements from the data in this project to conceptualise this DCR practice. The principles are reviewed and their application in the South African case is explored alongside their contribution to social justice and decolonisation.
The chapter considers social justice as a contested term that has been influenced historically by various dominant visions and perspectives (Capeheart & Milevanovic, 2007). These visions have tended to universalise just criteria in order to assess and seek a ‘perfect society’ from above—usually from an elitist and paternalist social class. However, this book presents an incomplete vision of justice that must be contextualised for us to create a public debate and scrutinise perspectives that do not necessarily need to be unified (Sen, 2011). The chapter argues that to achieve social justice in knowledge production and research practices within higher education we do not need to create a universal application of DCR.
9. Redrawing Our Epistemic Horizon
Authors: Martinez-Vargas Carmen 
Published: January 2022

The concluding chapter focuses on the book’s specific contributions to scholarly knowledge. It considers the book’s conceptual/empirical contributions, such as the creation of a participatory capabilities-based research process (De Sousa Santos, 2015). The second section highlights the book’s methodological contributions. It focuses on the case study, and certain limitations of current participatory practices. The third section focuses on pedagogical contributions in the classroom, alongside possible applications in educational policy. Here diverse uses and applications are highlighted, broadening the use of DCR as a pedagogical tool, for instance as a guide for creating context-relevant curriculums. In summary, this section contemplates the implications of using DCR for institutional practices and policies.
To conclude, the chapter outlines the future directions of DCR and how these practices may be expanded in the field of participatory research. It compares other traditions of participatory research, highlighting DCR’s possibilities and limitations, and the centrality of networks for the progression and application of this tool in the future.
A 10-Year Climatology of Midlevel Mesoscale Vortices in China
Authors: Shu Yu , Sun Jisong , Chenlu Jin 
Published: January 2022

Abstract
The mesoscale vortex (MV) is an important rain-producing system. In this study, the reanalysis data and satellite precipitation products are used to classify MVs into three categories: mesoscale convective vortex (MCV), mesoscale stratiform vortex (MSV), and mesoscale dry vortex (MDV). Then, these three categories of midlevel MVs in China from 2007 to 2016 are investigated. A total of 21 053 MVs are obtained. Most MVs form in the northwest of parent convection, and 45% of MVs generate secondary convection. The Tibetan Plateau is the main MV source region. Steered by the westerlies, MVs mainly move eastward. MCV is active in summer, MDV in winter, and MSV in spring and autumn. MCV diurnal variations are closely related to local topography, and MDVs mainly form around midnight. Composite analyses show that MCVs form near the high-value center of convective available potential energy at the development stage of parent convection. The composite MCV forms near the low pressure trough and the thermal ridge at 500 hPa, and a low-level jet exists to the south of the MCV center. At the initiation and maturity stages of MCV, strong convergence and divergence respectively exist at low levels and 400 hPa. The vortex circulation mainly locates near 500 hPa. Above the vortex is a warm core associated with the latent heat release, and below is a cold anomaly related to the cold pool. In the downshear region, there is strong low-level convergence and ascending motion, higher humidity, and greater latent heat release, which favor the formation of secondary convection.