bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mid to Long-term Echocardiographic Follow-up of Patients Undergoing Transcatheter Tricuspid Valve-in-Valve Replacement for Degenerated Bioprosthetic Valves: First Single-Center Report from Iran
Authors: Sahebjam Mohammad , Zeinali Alimohammad Haji , Abbasi Kyomars , Borjian Solmaz 
Published: October 2022

Background: Transcatheter tricuspid valve-in-valve (TTViV) replacement has become an alternative treatment in high-risk patients with bioprosthetic valve degeneration. This is the first report on the mid to long-term echocardiographic findings of patients who underwent TTViV replacement in a cardiac referral center in Iran.
Methods: Data of 12 patients, consisting of 11 women and 1 man, who underwent TTViV replacement between 2015 and 2021 were reviewed retrospectively. The patients underwent echocardiography before the procedure and at a mean follow-up time of 3.17±1.75 years.
Results: All the patients had New York Heart Association (NYHA) function class III/IV before TTViV. Six patients had tricuspid regurgitation, 1 had tricuspid stenosis, and 5 had both. All the patients had successful TTViV. The mean time from the initial valve surgery to TTViV was 6.25±2.45 years. At follow-up, 2 patients had died: 1 due to COVID-19 pneumonia and 1 without a known cause. The remaining 10 patients experienced improvements in the NYHA functional class. Echocardiographic measures showed significant improvements. Transvalvular mean gradient pressure decreased from 7.08±1.98 mm Hg to 5.29±1.63 mm Hg (P=0.028), tricuspid valve pressure half time decreased from 245.00±49.46 ms to 158.64±57.41 ms (P=0.011), tricuspid regurgitation gradient decreased from 39.91±7.31 mm Hg to 26.72±8.99 mm Hg, and left ventricular ejection fraction increased from 47.71±4.70% to 49.79±4.58% (P=0.046). There was no significant paravalvular or transvalvular leakage at follow-up.
Conclusion: This is a single-center report on the mid and long-term echocardiographic follow-up of patients after TTViV replacement. Our study showed that TTViV was a safe and efficient method in treating high-risk patients with degenerated bioprosthetic tricuspid valves and had favorable echocardiographic and clinical results.
The effects of E-learning based on a creatively cooperative method on student’s self-regulation ability in mathematics
Authors: Hidajat Flavia Aurelia 
Published: October 2022

This study aims to determine the effect of the creatively cooperative learning method on students’ self-regulation abilities in mathematics. This study employed quantitative research with a One-Group Posttest-only design. The research participants were 93 students from the seventh grade at a secondary school. The data were collected using a mathematical problem-solving test and a self-regulated ability questionnaire. The data were analyzed using linear regression analysis. This study indicates that the implementation of the creatively cooperative learning method positively influences students’ self-regulated abilities in mathematics. This study informs educators about the importance of creatively cooperative learning methods to improve students’ self-regulation abilities in mathematics and achievement. Thus, educators can combine the creatively cooperative learning method to make effective and suitable teaching materials or learning plans.

Keywords: mathematics learning; self-regulation ability; creative cooperative; learning methods; students’ creativity
Culture of Primary Human Lung Microvascular Endothelial Cells
Authors: Vitucci Eva CM , McCullough Shaun D. 
Published: October 2022

Abstract
This protocol describes the thawing, culturing, and cryopreservation of primary human lung microvascular endothelial cells (pMVECs). Disclaimer: The contents of this article have been reviewed by the US Environmental Protection Agency and approved for publication and do not necessarily represent Agency policy. Mention of trade names or commercial products does not constitute endorsement or recommendations for use. NOTE: There is a consolidated PDF version of this protocol in the supplementary files section below.
Journal of Insect Conservation Survival of eggs to third instar of late-summer and fall-breeding monarch butterflies (Danaus plexippus) and queen butterflies (Danaus gilippus) in north Texas
Authors: Scott Alyx , Contreras Kelsey , Stevenson Misty , Hudman Kalynn L. , Kopachena Jeffrey G. 
Published: October 2022

Abstract
Introduction: Eastern migratory monarch butterflies (Danaus plexippus) have declined over 80% in recent years, but little is known about fall reproduction in the southern U.S. where monarchs may compete with queen butterflies (Danaus gilippus).
Aims/Methods: We provide data on the survival to third instar, associated arthropods, and phenology of fall breeding monarchs and queens in Texas.
Results: Monarch and queen survival was high, but varied among years. Oleander aphids (Aphis nerii), jumping spiders (Salticidae), and red imported fire ants (Solenopsis invicta) had minor negative effects on survival. The abundance of monarchs and queens on the study site peaked three to four weeks before the main passage of monarchs in the area. Queens had similar phenology and exhibited a migratory pattern similar to monarchs but on a smaller scale.
Discussion: Survival of fall monarchs is high and likely to be important for winter roost recruitment. Fall egg survival was not greatly affected by any particular arthropod taxon, but may be affected by precipitation. Fall reproduction is a response to available host plants and likely adaptive. The timing of oviposition enables pupae to eclose in time for successful migration to winter roosts.
Implications for Insect Conservation: Management of Asclepias viridisand other native milkweeds to facilitate fall reproduction is important for the recovery of monarchs because it buffers variable productivity occurring further north and contributes significantly to overwintering populations. Management should use mowing and burn schedules that promote high quality host plants. Populations of queens should be monitored for their potential to compete with monarchs especially in response to the potential impacts of parasite resistance and climate change.
Hip arthroplasty for unstable femoral trochanteric fractures using the direct anterior approach
Authors: Baba Tomonori , Banno Sammy , Watari Taiji , Shirogane Yuichi , Tanabe Hiroki , Ishii Seiya , Homma Yasuhiro , Kaneko Kazuo , Ishijima Muneaki 
Published: October 2022

Abstract
Background: This study aims to investigate the clinical outcome of unstable femoral trochanteric fractures treated by hip arthroplasty through direct anterior approach (DAA).
Methods: The subjects were patients with unstable femoral trochanteric fractures who were independently ambulatory before injury. Twenty-two patients who underwent hip replacement between 2019 and 2021 (arthroplasty group), and 22 patients treated by osteosynthesis between 2016 and 2018 (osteosynthesis group) were compared.
Results: Regarding complications, reoperation, dislocation, or infection did not occur, but over telescoping of the lag screw larger than 10 mm was noted in 4 patients (18.2%) in the osteosynthesis group. No significant difference was noted in the mean Barthel Index score on admission, but it was significantly different at discharge (arthroplasty group: 71.4±17.3, osteosynthesis group: 48.0±23.1, P<0.01). One year after surgery, walking ability before injury was maintained at 71.4% in the arthroplasty group and 36.4% in the osteosynthesis group (P<0.05).
Conclusion: Hip arthroplasty through DAA did not cause postoperative dislocation. For unstable trochanteric fractures, patients who underwent hip arthroplasty through DAA had a higher Barthel index at discharge and a higher maintenance rate of walking ability at 1 year after surgery than those who underwent osteosynthesis. Hip arthroplasty through DAA is effective for the treatment of unstable femoral trochanteric fractures considering functional recovery of the hip joint.
Do early-life extreme weather experiences of CEOs
affect corporate climate strategies?
Authors: Szymczak Wiebke , Wagner Simone Andrea , Busch Timo 
Published: October 2022

Abstract
While the drastic physical impacts of climate change and related extreme weather events (EWEs) are increasingly apparent, little is known about long-term behavioral consequences of climate change-related experiences. In this study, we investigate whether extreme weather events experienced by CEOs during their early lives induce a systematic shift towards more climate-friendly professional decisions. Our sample covers decisions of 447 U.S. born Chief Executive Officers (CEOs) between 1991 and 2018. The results of our study reveal a significant positive effect of early-life EWE experiences on sustainability-related and climate-related corporate policies during a CEO's tenure. These findings are robust to different proxies and model specifications. Our results provide evidence that extreme weather experiences have long-lasting effects on climate-related attitudes and thereby moderate the willingness to act with respect to climate change.
Virtual Reality Enables Rapid and Multi-Faceted Retinal Function Screening
Authors: Labkovich Margarita , Warburton Andrew , Cheng Christopher , Okome Oluwafeyikemi , Navarro Vicente , Serafini Randal , Valliani Aly , Reddy Harsha , Chelnis James 
Published: October 2022

Abstract

Background: Given global population growth and aging, it is imperative to prioritize early eye disease detection and treatment. However, the current eye specialist workforce capacity is not bridging the growing gap, making it important to consider alternative solutions for increasing eye screening capabilities. This study compared virtual reality (VR) vision screening exams that help evaluate retinal health, such as 24-2 perimetry, Ishihara color blindness, and Amsler grid tests, against their in-clinic counterparts.

Methods: 86 subjects were recruited from Mount Sinai’s ophthalmology clinic for a head-to-head comparison trial that was internally controlled across healthy controls and eyes with glaucoma and retinal disease.

Results:
Perimetry results from Humphrey Visual Field Analyzer (HVFA) and VR suprathreshold testing demonstrated a good sensitivity both overall (80% OD, 84% OS) and across control (86% OD, 89% OS), glaucoma (69% OD, 78% OS), and retinal disease (76% OD, 80% OS) groups. A Garway-Heath anatomical map showed an overall 70-80% agreement. Ishihara plate tests did not show a significant difference between the two testing modalities (p = 0.12; Mann-Whitney U test), which remained true across groups. Amsler grid testing differences were also non-significant (p = 0.81; Mann-Whitney U test), including each subgroup. Patient time required to complete VR exams was significantly improved (p<0.0001; Wilcoxon) compared to the gold standard tests.

Conclusions: All VR tests showed high sensitivity and percent agreement compared to in-office standards, indicating a promising potential for VR technologies in visual function screening for early identification of prevalent diseases such as glaucoma and retinal conditions.
Genomic association using principal components of morphometric traits in horses: identification of genes related to bone growth
Authors: Bastos Marisa Silva , Diaz Iara del Pilar Solar , Alves Jackeline Santos , de Oliveira Louise Sarmento Martins , de Oliveira Chiara Albano de Araújo , de Godói Fernanda Nascimento , deCamargo Gregório Miguel Ferreira , Costa Raphael Bermal 
Published: October 2022

Abstract

The measurement of morphometric traits in horses is important for determining breed qualification and is one of the main selection criteria in the species. The development of an index (HPC) that consists of principal components weighted by additive genetic values allows to explore the most relevant relationships using a reduced number of variables that explain the greatest amount of variation in the data. Genome-wide association studies (GWAS) using HPC are a relatively new approach that permits to identify regions related to a set of traits. The aim of this study was to perform GWAS using HPC for 15 linear measurements as the explanatory variable in order to identify associated genomic regions and to elucidate the biological mechanisms linked to this index in Campolina horses. For GWAS, weighted single-step GBLUP was applied to HPC. The eight genomic windows that explained the highest proportion of additive genetic variance were identified. The sum of the additive variance explained by the eight windows was 95.89%. Genes involved in bone and cartilage development were identified (SPRY2, COL9A2, MIR30C, HEYL, BMP8B, LTBP1, FAM98A, and CRIM1). They represent potential positional candidates for the HPC of the linear measurements evaluated. The HPC is an efficient alternative to reduce the 15 usually measured traits in Campolina horses. Moreover, candidate genes inserted in region that explained high additive variance of the HPC were identified and might be fine-mapped for searching putative mutation/markers.
Relationship between evacuation after the Great East Japan Earthquake and new-onset hyperuricemia: A 7-year prospective longitudinal study of the Fukushima Health Management Survey
Authors: Honda Kazuya , Okazaki Kanako , Tanaka Kenichi , Kobari Eri , Kazama Sakumi , Hashimoto Shigeatsu , Ohira Tetsuya , Sakai Akira , Yasumura Seiji , Maeda Masaharu , Yabe Hirooki , Hosoya Mitsuaki , Takahashi Atsushi , Harigane Mayumi , Nakano Hironori , Hayashi Fumikazu , Nagao Masanori , Shimabukuro Michio , Ohto Hitoshi , Kamiya Kenji , Kazama Junichiro J 
Published: October 2022

Abstract
The Great East Japan Earthquake occurred in Japan on March 11, 2011, with a nuclear accident occurring at the Fukushima Daiichi Nuclear Power Plant afterward. The disaster constrained many evacuees to change their lifestyles. However, the effect of evacuation on the new-onset of hyperuricemia have not been sufficiently elucidated. We aimed to assess the association between evacuation and new-onset hyperuricemia after the earthquake based on the Fukushima Health Management Survey from a lifestyle and socio-psychological perspective. A longitudinal study examined data collected from 18,140 residents (6,961 men and 11,179 women) with non-hyperuricemia who underwent both the Comprehensive Health Check and the Mental Health and Lifestyle Survey between 2011 and 2017. Using a Cox proportional hazards regression model analysis, we estimated associations between new-onset hyperuricemia and lifestyle- and disaster-related factors, including evacuation. We defined hyperuricemia as uric acid levels > 7.0 mg/dL for men and > 6.0 mg/dL for women. A total of 2,996 participants (1,608 men, 23.1%, 1,388 women, 12.4%) newly developed hyperuricemia during a median follow-up of 4.3 years. This study observed significant associations between evacuation and onset of hyperuricemia in women (adjusted hazard ratio 1.18, 95% confidence interval, 1.05–1.32, p = 0.007), but not in men (adjusted hazard ratio 1.11, 95% confidence interval, 0.99–1.24, p = 0.067). Evacuation after a natural disaster is an independent risk factor for the new-onset of hyperuricemia in women.
Clinical response to three different doses of epidural morphine analgesia in frail older adults undergoing lower abdominal cancer surgery: a randomized clinical trial
Authors: Shawqi Muhammad , Mohamed Sahar Abdel-Baky , A Essam Sharkawy , Hetta Diab 
Published: October 2022

Abstract
Background: Epidural morphine is considered one of the potent drugs that used for post operative analgesia; however, side effects of its usage are dose-related and exaggerated in the elderly.
Methods: 88 elderly patients undergoing lower abdominal cancer surgery were divided into four equal groups received either, placebo (group Morphine 0, N = 22), or 1.5 mg epidural morphine (Morphine 1.5, N = 22), or 3 mg epidural morphine (Morphine 3, N = 22), or 4.5 mg epidural morphine (Morphine 4.5, N = 22) immediately preoperatively, 24 hours and 48 hours postoperatively. Cumulative intravenous PCA morphine consumption, VAS pain scores, modified Ramsay Sedation Score, nausea, vomiting, and pruritis were evaluated.
Results: The mean cumulative IV PCA morphine consumption (mg) in the first postoperative 72 hours was significantly decreased in all interventional groups, Morphine 1.5 mg, Morphine 3 mg and morphine 4.5 mg, compared to Morphine 0, P < 0.001 (Bonferroni corrected). However, non-significant reduction was observed between 3 mg epidural morphine group Vs. 4.5 mg group as P value = 0.191 (Bonferroni corrected). 0 mg Vs. 1.5 mg; 38.136 (4.8037) Vs. 27.182 (5.6115), 0 mg Vs. 3 mg; 38.136 (4.8037) Vs. 9.182 (3.5273), 0 mg Vs. 4.5 mg; 38.136 (4.8037) Vs. 6.273 (3.3407), 1.5 mg Vs. 3mg; 27.182 (5.6115) Vs. 9.182 (3.5273), 1.5 mg Vs. 4.5 mg; 27.182 (5.6115) Vs. 6.273 (3.3407), 3 mg Vs 4.5 mg; 9.182 (3.5273) Vs. 6.273 (3.3407).
The VAS score of pain intensity during cough in the first postoperative 72 hours was significantly decreased in 3 mg and 4.5 mg treatment groups compared to the control group. However, no significant difference was observed between 0 mg group Vs. 1.5 mg group or between 3 mg group Vs. 4.5 mg group.
Patients in epidural morphine 4.5 mg group showed an increased level of sedation compared to all other groups. Nausea score was similar across both control and treatment groups. Vomiting and pruritis scores were similar across all the treatment groups but significantly higher than the placebo group.
Conclusion: Epidural morphine at a dose of 3 mg, for older adults undergoing lower abdominal cancer surgery, is the balanced optimal dose considering its analgesic efficacy and side effects.
Trial registration: clinicaltrials.gov with ID number NCT0431687, Registered 20 March 2020, https://clinicaltrials.gov/ct2/show/NCT04316871
Effect of premature infant oral motor intervention(PIOMI) combined with music therapy on feeding progression of premature infants: a randomized control trial
Authors: Shokri Elmira , Zarifian Talieh , Soleimani Farin , Knoll Brenda Lessen , Mosayebi Ziba , Noroozi Mahdi , GhasrHamidi Kiana 
Published: October 2022

Abstract
Background: To explore the clinical effect of premature infant oral motor intervention(PIOMI) combined with music therapy on feeding progression of premature infants.
Method: Premature infants with post-menstrual ages between 26-30 weeks were included in the study. 52 participants were random divided into the intervention and control groups. All infants received PIOMI, and the intervention group had additional music therapy. The participants of the two groups were compared based on weight gain, feeding progression, Preterm Oral Feeding Readiness Scale (POFRAS), milk volume and length of hospitalization.
Result: Intervention group reached independent oral feeding earlier, length of hospitalization was shorter, and POFRAS score was higher. There was no difference in weight gain between groups.
Conclusion: PIOMI combined with music therapy can improve feeding progression of premature infants by 8 days and reduce length of stay by 6 days.
Muscle Architecture of Leg Muscles: Functional and Clinical Significance
Authors: Kaur Gurpreet , Lalwani Rekha , Khan Manal M , Athavale Sunita Arvind 
Published: October 2022

Abstract
Purpose
Architectural properties of the muscles are the prime predictors of functional attributes and force-generating capacity of the muscles. This data is vital for musculoskeletal modelling and selecting the appropriate muscle-tendon units for tendon transfers.
Cadaveric data for architectural properties is the gold standard and primary input for musculoskeletal modelling. There is a paucity of these datasets, especially in the leg muscles.
Methods
Sixty muscles of the anterior & lateral compartments from twelve formalin-fixed lower limbs were studied for gross architecture including the peculiar fibre arrangements and architectural properties of muscles. Muscle weight, Muscle length, Fibre length, Pennation angle & Sarcomere length were measured. Normalised fibre length, Fibre length to muscle length ratio (FL/ML Ratio), and the physiological cross-sectional area (PCSA) were calculated from the obtained data.
Results
Muscles displayed a combination of architectural strategies and were partly fusiform and partly pennate. The tibialis anterior and peroneus longus were the heaviest muscles in their respective compartments and showed more extensive origin from the nearby deep facial sheets.
Long fibre length and less pennation angle were seen in muscles of the extensor compartment. Muscle power was highest in the tibialis anterior and peroneus longus and least in the Extensor hallucis longus.
Conclusions
Arching of the foot and eversion are peculiar to humans and recent in evolution. Due to the functional demand of maintaining the medial longitudinal arch and eversion, the Tibialis Anterior and Peroneus Longus have more muscle weight, and longer PCSA and hence are more powerful.
Extensor compartment muscles were architecturally more suited for excursions because of the long fibre length and less pennation angle.
This study contributes baseline normative data for musculoskeletal modelling platforms and simulation tools- an emerging area in biomechanics and tendon transfers.
Defining the Mixing Zone and Dilution at Lifting Drainage Water Joints Using CORMIX Model
Authors: Agrama Asmaa , El-Gamal Tallat 
Published: October 2022

Abstract
Background: Limited water resources with the gradual increase of water demand led to higher dependence on non-conventional water resources. The increasing pollutants in the drainage water restricted the reuse of this resource, and to maintain the quality of the fresh water, rigid laws are currently applied for mixing the drainage water with the fresh water. Such rigid laws led to hanging up the operation of many lifting stations that coasted big investment and which was lifting more than 2.0 BCM/day to the irrigation network. Mathematical models offer more flexible alternative for maintaining the water quality of the fresh water through defining the mixing zone between lifted drainage water and the receiving ambient. Cornell Mixing Zone Expert System (CORMIX) model is a mathematical simulation model, which provides the quantitative predictions for pollutants dilution. The model has three modules depending on outfall characteristics (CORMIX1, 2 and 3). CORMIX3 for surface discharge was used in this study. The model was applied to define the mixing zone between the lifted drainage water from Mehalet Rough pumping station and the fresh water in Mit Yazid canal. Two water quality (WQ) parameters were assessed; biochemical oxygen demand (BOD) and total dissolved solids (TDS).
Results: The simulation results verified that the two investigated parameters met WQ standards for the Egyptian law 48/1982 at a distance of 448.36 meter and 4.46 meter respectively. As the first municipal station is 3.2 km downstream the pumping station, the lifted drainage water could be accepted regardless its low quality according to these parameters.
Conclusions: The results illustrated the importance of using such model to define the suitable location for using the fresh water after mixing with point sources, and for an efficient implementation of integrated water management.