bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modelling skeletal pain harnessing tissue engineering
Authors: Iafrate Lucia , Benedetti Maria Cristina , Donsante Samantha , Rosa Alessandro , Corsi Alessandro , Oreffo Richard O. C. , Riminucci Mara , Ruocco Giancarlo , Scognamiglio Chiara , Cidonio Gianluca 
Published: August 2022

Abstract
Bone pain typically occurs immediately following skeletal damage with mechanical distortion or rupture of nociceptive fibres. The pain mechanism is also associated with chronic pain conditions where the healing process is impaired. Any load impacting on the area of the fractured bone will stimulate the nociceptive response, necessitating rapid clinical intervention to relieve pain associated with the bone damage and appropriate mitigation of any processes involved with the loss of bone mass, muscle, and mobility and to prevent death. The following review has examined the mechanisms of pain associated with trauma or cancer-related skeletal damage focusing on new approaches for the development of innovative therapeutic interventions. In particular, the review highlights tissue engineering approaches that offer considerable promise in the application of functional biomimetic fabrication of bone and nerve tissues. The strategic combination of bone and nerve tissue engineered models provides significant potential to develop a new class of in vitro platforms, capable of replacing in vivo models and testing the safety and efficacy of novel drug treatments aimed at the resolution of bone-associated pain. To date, the field of bone pain research has centred on animal models, with a paucity of data correlating to the human physiological response. This review explores the evident gap in pain drug development research and suggests a step change in approach to harness tissue engineering technologies to recapitulate the complex pathophysiological environment of the damaged bone tissue enabling evaluation of the associated pain-mimicking mechanism with significant therapeutic potential therein for improved patient quality of life.
Graphical abstract
Rationale underlying novel drug testing platform development. Pain detected by the central nervous system and following bone fracture cannot be treated or exclusively alleviated using standardised methods. The pain mechanism and specificity/efficacy of pain reduction drugs remain poorly understood. In vivo and ex vivo models are not yet able to recapitulate the various pain events associated with skeletal damage. In vitro models are currently limited by their inability to fully mimic the complex physiological mechanisms at play between nervous and skeletal tissue and any disruption in pathological states. Robust innovative tissue engineering models are needed to better understand pain events and to investigate therapeutic regimes
Evaluation of Quality of Life After Inflatable Penile Implantation and Analysis of Factors Influencing Postsurgery Patient Satisfaction
Authors: Luna Eusebio , Rodriguez Dayron , Barrios Dailianys , Hernandez Hunter , Bianco Fernando , Gheiler Edward 
Published: August 2022

ABSTRACT

Background
Most of the published literature addressing the satisfaction postinflatable penile implant (IPP) placement includes non-validated surveys.

Aim
The study aims to report the survey outcomes of the English version of The QoLSPP and to evaluate the different factors that could influence these results.

Methods
Patients who underwent inflatable penile implant placement from January 2017 to December 2019 received a survey by phone and had a visit scheduled no sooner than 27 months after surgery. In the clinic, they were inquired about the penile size and underwent measurements of postoperative penile length and diameter. The survey responses were rated from zero to 5 following QoLSPP, and answers ≥3 were considered positive. An evaluation of the factors influencing the quality-of-life score of patients post-IPP placement was performed. Variables included age (&lt;60, 60–70, &gt;70), BMI classification, Charlson Comorbidity Index, diabetes diagnosis, implant type (AMS 700CX vs Titan), ED etiology, revisions, postoperative time in months (&lt;30, 30–40, &gt;40) and preoperative vs postoperative penile dimensions in those who attended the clinic.

Outcomes
The primary outcome was to obtain accurate patient-reported satisfaction after inflatable penile implantation.

Results
Within the timeframe, 542 patients underwent first-time IPP placements. Of that group, 322(n) completed the surveys, and 109 patients attended the clinic to compare preoperative vs postoperative dimensions. Of note, 67 (61.4%) and 54 (49.4 %) demonstrated enlargement in length and diameter, respectively. Conversely, 12 (11%) and 4 (3.7%) experienced a shortening in length and girth. We found 66 (60.5%) patients who complained about a penile size decrease after the intervention. The survey had a positive response in 93.1% of the cases. There were no statistically significant differences in positive responses concerning the variables investigated. The subpopulation analysis of the penile-sized group neither showed response variations.

Clinical implications
The investigation allowed a better understanding of patient-reported satisfaction post-IPP placement.

Strengths & Limitations
The performance of all the procedures in a high-volume center by a single surgeon limits its generalization.

Conclusion
The overall results after IPP surgery are positive in most patients who underwent the procedure and the variables investigated did not influence the overall outcomes of the QoLSPP survey in the study.
The Cognitive Structure of Emotions
Authors: Ortony Andrew , Clore Gerald L. , Collins Allan 
Published: August 2022

More than 30 years after its initial publication, this new edition of The Cognitive Structure of Emotions refines and updates Ortony, Clore, and Collins's OCC model of emotions. Starting from a three-way classification of construals of the world––events, the attribution of responsibility for events, and objects––the authors propose a systematic account of emotion differentiation. Rejecting the oft-favored features of bodily feelings, emotion-related behaviors, and facial expressions as too intensity-dependent and insufficiently diagnostic, they provide a detailed analysis of emotion differentiation in terms of the cognitive underpinnings of emotion types. Using numerous examples, they explain how different variables influence emotion intensity, and show how emotions can be formalized for computational purposes. Now with a contributed chapter describing the OCC model's influence, this book will interest a wide audience in cognitive, clinical, and social psychology, as well as in artificial intelligence and affective computing, and other cognitive science disciplines.
Collective Remembering and the Making of Political Culture
Authors: Liu James H. 
Published: August 2022

Collective memory can make and break political culture around the world. Representations and reinterpretations of the past intersect with actions that shape the future. A nation's political culture emerges from complex layers of institutional and individual responses to historical events. Society changes and is changed by these layers of memory over time. Understanding them gives us insight into where we are today. Encompassing examples from colonization and decolonization, revolving around the critical junctures of the world wars, this book illustrates how collective memory is produced and organized, through commemoration, through monuments, and through individuals sharing stories. Using concrete examples from around the world, James H. Liu shows how different disciplines can come together through shared concepts like narratives and generational memories to provide mutually enriching perspectives on how political culture is made, and how it changes.
Contribution of tip and hub vortex to the structural response of a marine rudder in the propeller slipstream
Authors: Magionesi F. , Dubbioso G. , Muscari R. 
Published: August 2022

The structural design of the rudder, traditionally based on quasisteady loads generated during worst manoeuvres, should account for load fluctuations associated with the interaction with the wake of the propeller in order to comply with the more stringent requirements on ship vibration and noise pollution. In this context, the present work analyses the dynamic response of a marine rudder located in the wake of the INSEAN E779A propeller by the one-way fluid–structure interaction approach. The time-dependent pressure distribution on the rudder, obtained through detached eddy simulation, is used to evaluate the pressure field that is the input for a structural solver to determine the resulting deformations and stresses. The computations consider the propeller at moderate loading, and rudder deflection angles at neutral and

$4^{\circ }$

. The analysis discusses the different contribution of the tip and hub vortex of the propeller on the static and vibratory response of the rudder in the two configurations.
Cultivating “Care”: Colonial Botany and the Moral Lives of Oil Palm at the Twentieth Century’s Turn
Authors: Rudge Alice 
Published: August 2022

AbstractThis paper draws on archival research to trace the techniques used by scientists and government officials involved with palm oil at the turn of the twentieth century. For them, mundane practices of “carefulness” were paramount as they worked on collecting, identifying, marketing, and improving the oil palm. But they also applied this so-called care to people: care of the oil palm was thought to presuppose care of the “native,” providing a correction for what were seen as “careless” local manners of cultivation. Colonial techniques of care thus sought to encompass both plants and peoples within contemporary liberal rhetorics of efficiency and moral improvement. This embodies how scientific and political care can interlink through their undersides of control, exploitation, and domination, which remain obscured by narratives of care themselves. Examining these links between commodity histories and scientific techniques is therefore essential for understanding environmental and social concerns regarding oil palm plantations today. An awareness of the afterlives of colonial discourses might encourage a more critical “care” in response to these issues today, challenging taken-for-granted notions of the benefits of corporate care.
Wiggins on Ethical Objectivity and ‘Des Cannibales’
Authors: Etinson Adam 
Published: August 2022

AbstractThis short essay offers a commentary on Chapter 11 of David Wiggins’,Ethics(2006). The essay asks how we should interpret Wiggins’ defense of ethical ‘objectivity’ given his subjectivist metaethics. An interpretation is drawn from Sharon Street's work on metaethical constructivism, of which Wiggins’ view is taken to be one variety.
Ageism: the importance of the linguistic concept for the construction of the experience
Authors: Okun Sarit , Ayalon Liat 
Published: August 2022

AbstractThis study investigated if people are acquainted with the term ‘ageism’, and to what extent acquaintance with this term corresponds with reports of discrimination, due to age. The study included an online survey, answered by 1,025 Israeli respondents. The questionnaire began by asking the respondents to define ‘What is ageism?’ (gilanut in Hebrew) and then to mark ‘If and what types of discrimination they experienced in the last year’. Subsequently, we defined and demonstrated the term ageism and asked participants to share experiences of this phenomenon; 457 (45%) participants were not familiar with the term. In the group that was unfamiliar with the term, only 46 (10%) reported that they had such experiences. In the group that was acquainted with the term, 208 (30%) reported that they had experienced ageism. In contrast, once the term, ageism, was defined and demonstrated in the survey, 638 (62%) respondents shared experiences of ageism in their lives. Of those who shared their experiences of ageism, 202 (31%) were initially unfamiliar with the term. The study's results show that there is an association between the linguistic representation of the phenomenon of ageism and reports of ageism. In the wider sense, the study shows that language and words have the power to help people understand and interpret social and human experiences.
Les industries diverses en 1951
Authors: Pâquet Roger 
Published: August 2022

La production d'énergie est en relation directe avec le niveau d'activité du pays. Aussi, une augmentation nette est-elle apparue depuis que les événements de Corée et les perspectives de réarmement ont donné une impulsion nouvelle à l'économie.Dans le secteur de l'électricité, si l'on élimine la variation saisonnière, il ressort clairement que le volume total d'énergie électrique absorbée par les réseaux a pris un nouvel essor à partir de septembre 1950 et qu'un rythme d'accroissement rapide s'est maintenu jusqu'en octobre 1951, pour fléchir toutefois au cours des trois derniers mois de l'année.
La grève Phénomène èconomique et sociologique Étude inductive des conflits du travail en Belgique de 1920 à 1940
Authors: De Wasseige Yves 
Published: August 2022

La grève est une forme de conflit social courante dans la vie économique d'un pays industriel. Les groupes sociaux patronal et ouvrier, que la grève oppose l'un à l'autre, lui accordent une grande importance; l'opinion publique et les gouvernements s'y intéressent de plus en plus.Le patronat, c'est-à-dire le groupe qui détient la gestion des entreprises, redoute la grève car il y voit la cause d'interruptions dans le travail et, conséquetnment, de pertes dans la production et de réductions dans les profits; il ne la considère pas comme une réalité inhérente au système économique lui-même, mais l'attribue à « l'action des meneurs » et lui trouve fréquemment un caractère « politique ». Cette opinion est un réflexe d'auto-défense : le patronat ne comprend pas ou veut nier la force grandissante d'un autre groupe social sur un terrain qui jadis lui était entièrement réservé : le terrain économique.
Les religieuses du diocèse de Tournai. Étude sociologique de leur provenance
Authors: Mattez Marie-Thérèse 
Published: August 2022

Les modes d'expression de la vitalité religieuse sont nombreux : participation au culte, aumônes, respect des règles morales. Un des plus typiques, parce que plus total et plus absolu, est la consécration personnelle à Dieu réalisée dans la vocation sacerdotale et religieuse.La vocation religieuse a donné lieu à de multiples formes de vie communautaire. L,e cadre conventuel est entièrement ordonné à la constitution d'un milieu favorable à la recherche de Dieu ou de la perfection. C'est ce phénomène religieux de la vocation, réalisé dans une forme de vie canoniquement définie, qui retient notre attention.
La conjoncture économique de la Belgique
Authors: Woitrin Michel 
Published: August 2022

Au sein du marché commun, la conjoncture économique belge est soumise à des pressions baissières plus fortes que celles affectant les autres pays membres; la Belgique est d'ailleurs en récession nette depuis le printemps de 1957, tandis que la France et l'Allemagne commencent seulement à dépasser leur maximum conjoncturel général.Le maintien de la haute conjoncture allemande est apparemment dû en partie au jeu de la loi des débouchés, dans un pays recevant un afflux permanent de main-d'œuvre qualifiée; il s'avère aussi que la position compétitive de l'Allemagne est très forte à ses prix et salaires actuels, ce qui peut d'ailleurs être en rapport avec les pressions de population. L'industrie lourde allemande souffre cependant de phénomènes de crise.
Aspects de la perception sociale à travers l'œuvre de quelques auteurs actuels
Authors: Lefebvre Magdeleine 
Published: August 2022

Il est actuellement très souvent question de la perception dans la littérature psychologique comme dans la littérature sociologique.L'accent est mis de plus en plus sur l'aspect social de cette activité, soit à propos du milieu, soit à propos du monde phénoménal ou du perceveur lui-même.Depuis quelques années, un mouvement que KRECH appelle new look se développe autour de la perception. Ce mouvement insiste pour que le phénomène perceptuel soit étudié dans la vie réelle et non plus dans le monde artificiel du laboratoire. Les tenants de cette approche critiquent les anciennes méthodes de travail dans ce domaine et principalement celles des gestaltistes qui accordaient relativement peu d'importance à l'expérience individuelle passée, insistant surtout, d'une part, sur les structures internes innées, d'autre part, sur les facteurs objectifs extérieurs. Le mouvement actuel, au contraire, voit dans l'expérience passée du sujet un facteur important qui influence fortement certaines perceptions.
Le mouvement social en 1958
Authors: Vandamme Jacques 
Published: August 2022

L'évolution économique moins favorable qui a prévalu tout au long de l'année 1958 n'a pas manqué d'avoir de sensibles répercussions sur la situation sociale.La nature des rapports paritaires, les préoccupations sociales générales, l'orientation de la législation sociale se sont ressenties de la régression de l'emploi, de la stabilisation, voire de la diminution du niveau des rémunérations et de l'accroissement du chômage dans la plupart des branches d'activité. Comme les données à ce sujet constituent un préalable à l'explication de toute évolution sociale, nous nous efforcerons en premier lieu de rappeler leur signification exacte au cours de l'année écoulée.
L'industrie charbonnière beige en 1958
Authors: Valschaerts Henri 
Published: August 2022

L'année 1958 aura été l'une des plus sombres qu'ait connue l'industrie charbonnière belge dans toute son histoire.Le chômage a dû être instauré dans la plupart des mines du pays. Il en est résulté une baisse sensible de la production. Malgré cela, les stocks ont augmenté dans des proportions considérables. La concurrence sur les marchés extérieurs est devenue de plus en plus vive; nos exportations en ont subi les funestes conséquences. Dans le même temps, les importations se sont accrues; elles ont ainsi contribué à la détérioration du marché national. L'addition de ces divers éléments traduit l'importante diminution de la consommation apparente de charbons belges en 1958. Si l'on tient compte, en outre, des baisses de prix intervenues, dans le courant de l'année, au détriment de la rentabilité des entreprises, et de l'accroissement des charges financières résultant du chômage et des mises en stock, on saisira combien est inquiétante la situation de notre industrie charbonnière.
La construction et le marché immobilier en 1958
Authors: Bruyne Jean Pierre de 
Published: August 2022

Depuis 1951, l'activité de l'industrie de la construction s'est développée à un rythme assez régulier, le progrès de l'ensemble du secteur dérivant de l'alternance de périodes de grande activité et de ralentissement dans les domaines de l'habitation et des travaux publics.La construction d'habitation a décliné durant la période de prospérité traversée par l'économie belge à partir de 1954, sous l'effet des mesures prises par l'Etat dans le cadre de sa politique anticyclique (telles que la fixation de nouvelles conditions à l'octroi de primes, son intervention auprès des organismes parastataux pour qu'ils réduisent le volume de leurs crédits et élèvent les taux du financement).
Burkholderia cepacia complex outbreak linked to a no-rinse cleansing foam product, United States – 2017–2018
Authors: Seelman Sharon L. , Bazaco Michael C. , Wellman Allison , Hardy Cerisé , Fatica Marianne K. , Huang Mei-Chiung Jo , Brown Anna-Marie , Garner Kimberly , Yang William C. , Norris Carla , Moulton-Meissner Heather , Paoline Julie , Bicking Kinsey Cara , Kim Janice J. , Kim Moon , Terashita Dawn , Mehr Jason , Crosby Alvin J. , Viazis Stelios , Crist Matthew B. 
Published: August 2022

Abstract
In March 2018, the US Food and Drug Administration (FDA), US Centers for Disease Control and Prevention, California Department of Public Health, Los Angeles County Department of Public Health and Pennsylvania Department of Health initiated an investigation of an outbreak of Burkholderia cepacia complex (Bcc) infections. Sixty infections were identified in California, New Jersey, Pennsylvania, Maine, Nevada and Ohio. The infections were linked to a no-rinse cleansing foam product (NRCFP), produced by Manufacturer A, used for skin care of patients in healthcare settings. FDA inspected Manufacturer A's production facility (manufacturing site of over-the-counter drugs and cosmetics), reviewed production records and collected product and environmental samples for analysis. FDA's inspection found poor manufacturing practices. Analysis by pulsed-field gel electrophoresis confirmed a match between NRCFP samples and clinical isolates. Manufacturer A conducted extensive recalls, FDA issued a warning letter citing the manufacturer's inadequate manufacturing practices, and federal, state and local partners issued public communications to advise patients, pharmacies, other healthcare providers and healthcare facilities to stop using the recalled NRCFP. This investigation highlighted the importance of following appropriate manufacturing practices to minimize microbial contamination of cosmetic products, especially if intended for use in healthcare settings.
Treatment of Presumed Hyperkalemia in the Prehospital Setting
Authors: McArthur Robert , Rafique Zubaid , Ward Brad , Rodriguez Luis , Dickson Robert , Patrick Casey 
Published: August 2022

AbstractIntroduction:Hyperkalemia (HK) is common and potentially a life-threatening condition. If untreated, HK can progress to ventricular arrhythmia and cardiac arrest. Early treatment reduces mortality in HK. This study evaluates a novel protocol for identification and empiric management of presumed HK in the prehospital setting.Methods:This was a retrospective, observational chart review of a single, large, suburban Emergency Medical Services (EMS) system. Patients treated for presumed HK, with both a clinical concern for HK and electrocardiogram (ECG) changes consistent with HK, from February 2018 through February 2021 were eligible for inclusion. Patients were excluded if found to be in cardiac arrest on EMS arrival. Empiric treatment of HK included administration of calcium, sodium bicarbonate, and albuterol. Post-treatment, patients were placed on cardiac monitoring and adverse events recorded enroute to receiving hospital. Protocol compliance was assessed by two independent reviewers. Serum potassium (K) level was obtained from hospital medical records.Results:A total of 582 patients were treated for HK, of which 533 patients were excluded due to cardiac arrest prior to EMS arrival. The remaining 48 patients included in the analysis had a mean age of 56 (SD = 20) years and were 60.4% (n = 29) male with 77.1% (n = 37) Caucasian, 10.4% (n = 5) African American, and 12.5% (n = 6) Hispanic. Initial blood draw at the receiving facilities showed K >5.0mEq/L in 22 (45.8%), K of 3.5-5.0mEq/L in 23 (47.9%), and K <3.5mEq/L in three patients (6.3%). Independent review of the EMS ECG found the presence of hyperkalemic-related change in 43 (89.6%) cases, and five (10.4%) patients did not meet criteria for treatment due to lack of either appropriate ECG findings or clinical suspicion. No episodes of unstable tachyarrhythmia or cardiac arrest occurred during EMS treatment or transport.Conclusion:The study evaluated a novel protocol for detecting and managing HK in the prehospital setting. It is feasible for EMS crews to administer this protocol, although a larger study is needed to make the results generalizable.