bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of patients’ age and comorbidities on prostate cancer overdiagnosis in clinical practice
Authors: Beltrán Abraham , Parker Lucy , Moral-Pérez Irene , Caballero-Romeu Juan Pablo , Chilet-Rosell Elisa , Hernández-Aguado Ildefonso , Alonso-Coello Pablo , Ronda Elena , Gómez-Pérez Luis , Lumbreras Blanca 
Published: February 2025

Introduction
Overdiagnosis in PSA-based prostate cancer (PCa) screening is primarily studied in younger, healthier populations from clinical trials. This study aimed to evaluate the probability of overdiagnosis in PCa screening within a clinical practice context, focusing on its relationship with PSA levels, Gleason scores, and subsequent clinical procedures.

Methods
We conducted a retrospective cohort analysis of 1,070 asymptomatic men over 40 years old diagnosed with PCa between 2004 and 2022, following a positive PSA test. The patients were followed until December 31, 2022, with a median follow-up time of 5.7 years (IQR 3.2–8.6). The primary outcome was the probability of overdiagnosis, assessed through life expectancy and the Charlson Comorbidity Index, considering lead times of 5, 10, and 15 years.

Results
We found that patients with PSA levels >10 ng/dL and/or Gleason scores ≥8 were generally older and had more comorbidities than those with PSA levels 4–10 ng/dL and/or Gleason scores ≤7. The probability of overdiagnosis was significantly higher in patients with PSA levels >10 ng/dL (41.4%, IQR 21.5–73.9) and Gleason scores ≥8 (42.6%, IQR 14.9–38.9), compared to those with PSA levels 4–10 ng/dL (20.1%, IQR 12.8–30.4) and Gleason scores ≤7 (26.6%, IQR 23.6–68.6). Notably, 71.7% of patients did not receive pharmacological treatment. Patients with higher PSA levels also experienced greater radiation exposure from diagnostic imaging (median 19.9 mSv vs. 14.7 mSv, p = 0.004).

Conclusions
These findings underscore the high likelihood of overdiagnosis in older patients with elevated PSA levels and significant comorbidities, highlighting the need for careful consideration of patient comorbidities before PSA testing.
A new troglobitic species of Tychobythinus from Sicily with notes on some Italian species of the genus (Coleoptera, Staphylinidae, Pselaphinae)
Authors: Sabella Giorgio , Interlandi Marco Mariano , Nicolosi Giuseppe 
Published: February 2025

A new troglobitic species of the subfamily Pselaphinae (Coleoptera: Staphylinidae), Tychobythinus muxari n. sp., is described from Sicily (Ciavuli cave, Sant’Angelo Muxaro, Agrigento). Major diagnostic features are illustrated based on both male and female specimens. The new species shows some adaptations to cave life, i.e., pale brown color, setation consisting of long and flattened setae and suberect shorter setae, absence of wings, microphthalmia and elongated legs and antennae. It can be easily separated from the related taxa by the different shapes of the head and profemora and protibiae of the male, and of the aedeagus.
The new synonymy Tychobythinus cameratensis (Karaman, 1959) =  Tychobythinus gracilicornis (Raffray, 1914) (syn. nov.) is proposed. New data on morphology, taxonomy and/or distribution of T. andreinii (Dodero, 1919), T. controversus Poggi 1923, T. dentimanus (Reitter, 1884), T. foroiuliensis Pace, 1976, T. glabratus (Rye, 1870), T. gladiator gladiator (Reitter, 1885), T. majori (Holdhaus, 1905), T. mirandus (Dodero, 1919), T. myrmido (Reitter, 1882) and T. tibialis (Dodero, 1919) are provided.
Digital Therapeutic Combining Hypnosis and Diaphragmatic Breathing Intervention for Functional Abdominal Bloating: A Feasibility Study
Authors: Wang Xiao Jing , Philpot Lindsey , Ebbert Jon , Dilmaghani Saam , Loftus Conor , Fox Jean , Palsson Olafur 
Published: February 2025

INTRODUCTION:
Abdominal bloating is a difficult symptom to treat. Hypnotherapy and diaphragmatic intervention have separately shown benefit on bloating in prior work but have not been united into a single intervention. We aimed to obtain data on the potential therapeutic impact of a novel audio-recorded bloating treatment for bloating integrating hypnosis and diaphragmatic breathing, with proposed synergistic effect.

METHODS:
Patients with nonorganic bowel disorders with predominant bloating symptoms completed a digitally delivered 7-session audio-recorded hypnotherapy program without clinician involvement. The intervention combined bloating-targeted hypnotic suggestions and guided diaphragmatic breathing delivered under hypnosis, and was supplemented with interval self-guided breathing exercises. Participants completed online REDCap assessments at baseline, midtreatment, at end of treatment, and 3-month follow-up, evaluating symptom severity, gastrointestinal symptom-specific anxiety, overall anxiety/depression, and quality of life. Outcomes were assessed in an intention-to-treat manner with repeated measures analysis of variances (ANOVAs) with Bonferroni-adjusted pairwise post hoc tests.

RESULTS:
Of 23 patients who started treatment, 22 (95.6%) completed follow-up. Bloating severity on Irritable Bowel Syndrome-Symptom Severity Scale and Patient Assessment of Upper Gastrointestinal Symptom Severity Index showed reduction in bloating with large effect sizes (Cohen d of ∼0.8) at the end of treatment, as did Visceral Sensitivity Index bloating-related anxiety. At the end of treatment, 16 patients (69.6%) were Irritable Bowel Syndrome-Symptom Severity Scale treatment responders (≥30% symptom reduction) on bloating and 17 (73.9%) on overall bowel symptom severity. Anxiety, depression, and quality-of-life scores were unchanged. Outcome measures were fully maintained at the 3-month follow-up.

DISCUSSION:
Results suggest the therapeutic utility of a new cost-effective self-administered bloating intervention. A randomized controlled trial is planned to confirm these therapeutic effects.
As if grammar, discourse and prosody don’t interact: a comparative study of hypothetical manner clauses in English and Dutch
Authors: Van Praet Wout , Degand Liesbeth , Van linden An 
Published: February 2025

Abstract
This study examines hypothetical manner (HM) clauses in spoken English and Dutch. In both languages, HM clauses can assume different levels of grammatical and discursive (in)dependence, and different semantic-pragmatic functions. This study examines whether the grammatical-discursive configurations that English and Dutch allow for are associated with different prosodic profiles. To this end, the study investigates not just prosodic integration of the clause in the same intonation unit as the main/previous clause, but also potential pitch resets (or downsteps) at the start of the clause, average amount of pausing before the clause, and the pitch contour with which the clause is uttered. The study finds that, while syntactic status and semantic-pragmatic function interact, syntactic status is generally the better predictor of the prosodic realisation of the clause. Among syntactically independent clauses, few differences are found between discursively independent clauses (‘stand-alone insubordinates’) and discursively dependent ones (‘dependency shifts’). We argue, therefore, that these two clause types are similar from a communicative viewpoint, both marking ‘fresh starts’ in the discourse. Finally, the many observed similarities between English and Dutch indicate that meaningful generalisations can be made about the interactions between grammatical, discursive and prosodic profiles, at least for the two languages under investigation.
Artificial Intelligence and the “Great Machine” Problem: Avoiding Technology Oversimplification in Homeland Security and Emergency Management
Authors: Whyte Christopher 
Published: February 2025

Abstract
This research note deploys data from a simulation experiment to illustrate the very real effects of monolithic views of technology potential on decision-making within the Homeland Security and Emergency Management field. Specifically, a population of national security decision-makers from across the United States participated in an experimental study that sought to examine their response to encounter different kinds of AI agency in a crisis situation. The results illustrate wariness of overstep and unwillingness to be assertive when AI tools are observed shaping key situational developments, something not apparent when AI is either absent or used as a limited aide to human analysis. These effects are mediated by levels of respondent training. Of great concern, however, these restraining effects disappear and the impact of education on driving professionals towards prudent outcomes is minimized for those individuals that profess to see AI as a full viable replacement of their professional practice. These findings constitute proof of a “Great Machine” problem within professional HSEM practice. Willingness to accept grand, singular assumptions about emerging technologies into operational decision-making clearly encourages ignorance of technological nuance. The result is a serious challenge for HSEM practice that requires more sophisticated solutions than simply raising awareness of AI.
Characteristics of OA Diamond Journal Publishing in Non-English-Speaking Countries
Authors: Yoon JungWon , Rorissa Abebe , Kim Nayon , Chung EunKyung 
Published: February 2025

Abstract
Although global scholarly communication should include regional diversity it has been centered on English-language journals published in Western countries that wield strong economic power. Intending to reduce epistemological disparity, this study examined the characteristics of OA diamond journals (OADJ) published in non-English speaking countries (NESC). This study analyzed the OA Diamond Journals Study Dataset which cOAlition S commissioned. From the dataset 1,496 journals from 84 countries were assessed in terms of the official language of the journal’s publication country, the regions of the publication country, the country’s GDP, and the journal’s language. More than 80 % of OADJ were published in NESC and European countries, with Latin America and high-income countries as the main regions. OADJ in Latin America tended to be registered in Latin American index systems and considered international readers less important. Among OADJ published in Africa, Asia, and Eastern Europe, and those published in English, the intention of moving away from OADJ was stronger and journal impact and international readership were highly regarded. Based on the findings of this study the potential of OADJ was discussed, as were suggestions for enhancing the OADJ environment.
Rutile-type Ni–TiO2 nanocrystals with Ni-induced p-type channels for enhanced photocatalytic degradation of organic pollutants
Authors: Bashir Nimra , Habib Amir , Din Muhammad Imran , Ahmed Ejaz , Afzal Adeel 
Published: February 2025

Abstract
For the provision of clean water, and the prevention of toxic effects of organic pollutants, it is important to develop technologies for pollutant elimination and water remediation. This study presents the design of a high-performing photocatalyst under mild conditions, using aqueous solutions, without requiring thermal treatment. The catalyst comprised of phase-pure rutile-type Ni–TiO2 nanocrystals, with substantially reduced bandgap (E
g = 2.32 eV) at 0.92 at% doping of Ni2+ in TiO2, prepared via coprecipitation of Ni2+ and [TiCl4]– at T = 333 K. The Ni2+ introduces p-type channels, and lowers the E
g, thereby improving the photocatalytic elimination of methylene blue under natural sunlight. The analyses reveal a 255 % increase in photodegradation kinetics, with a rate constant of 3.72 × 10−2 min−1, at T = 310 K.
In vitro activity of ceftazidime-avibactam, ceftolozane-tazobactam, imipenem-relebactam, meropenem-vaborbactam and cefiderocol against carbapenemase-producing Enterobacterales from clinical isolates in a tertiary healthcare centre in Serbia
Authors: Mladenović-Antić Snežana , Veličković-Radovanović Radmila , Stojanović Predrag , Randjelović Marina , Djordjević Vukica 
Published: February 2025

AbstractThe aim of the study was to detect carbapenemase genes in clinically significant carbapenemase-producing Enterobacterales (CPE) and assess their susceptibility to newer antibiotics: ceftazidime-avibactam, ceftolozane-tazobactam, imipenem/relebactam, meropenem-vaborbactam, and cefiderocol. From January 2018 to February 2019, 866 Gram-negative bacilli were isolated, and among them 775 were identified as Enterobacterales. Out of the tested Enterobacterales, phenotypic testing revealed potential carbapenemase production in 95 isolates. A total of 56 clinically significant isolates were selected for molecular analysis. Species identification and antimicrobial susceptibility for conventional antibiotics was done using the VITEK 2 system, while carbapenemase genes were detected via Multiplex PCR. Antimicrobial susceptibility for newer antibiotics was determined by the MIC test strips. The predominant genotypes were blaNDM (39.3%) and blaOXA-48 (37.5%), with Klebsiella pneumoniae as the most prevalent producer (71.42%). Cefiderocol showed 100% effectiveness against all isolates. Ceftazidime-avibactam demonstrated high activity against OXA-48 and KPC producers (95.5% and 100% susceptibility, respectively). Meropenem-vaborbactam significantly improved susceptibility among NDM-. OXA-48/NDM-, and OXA-48-producing isolates, and imipenem-relebactam among OXA-48 CPE. Statistically significant differences in susceptibility were observed for OXA-48 and NDM producers to imipenem (P < 0.01), imipenem-relebactam (P < 0.001), and ceftazidime-avibactam (P < 0.001). In conclusion, the high prevalence of NDM-producing CPE strains significantly reduces the effectiveness of newer antibiotics. Cefiderocol appears to be the most effective therapeutic option, particularly for NDM producers, where it often represents the only viable treatment choice, while ceftazidime-avibactam is an effective option for OXA-48 producers. Statistically significant differences in susceptibility highlight the need for early detection of carbapenemases in clinical practice.
Tradiciones en el estudio del trabajo en plataformas digitales: una revisión de literatura
Authors: Cifuentes Leiton Diana Milec 
Published: February 2025

El fenómeno de la mediación de internet en la relación persona-trabajo exige analizar las formas de organización laboral que se presentan en circunstancias diferentes a las del trabajo tradicional. El trabajo en plataformas digitales es una de esas formas, por ello, el objetivo de este artículo de revisión de literatura fue analizar las perspectivas desde las que se ha abordado este concepto en el mundo científico. Para esta revisión de la literatura se optó por un enfoque cualitativo haciendo uso de un método metanarrativo, se utilizó la base de datos Scopus y procedimientos del Tree of Science para hallar un corpus de 80 documentos procesados con análisis de contenido y estadística descriptiva. Los hallazgos indican que el concepto se estudia principalmente desde dos tradiciones. La primera, describe que se trata de un nuevo tipo de trabajo que produce precarización laboral o de un nuevo sujeto trabajador que sufre ante condiciones de trabajo precarias; la segunda explicita que aún se precisan otros abordajes comprensivos para esta forma de trabajo. Se analizó el adjetivo nuevo encontrado en dichas tradiciones y la necesidad de enmarcar esta forma de organizar el trabajo desde una perspectiva histórica-económica. Se estipula que la complejidad del concepto abre la posibilidad de explorar otras comprensiones en futuras agendas investigativas.
Compras públicas sostenibles con el medio ambiente en Colombia: criterios ambientales y el objetivo 12 de desarrollo sostenible
Authors: Cardenas Poveda Margarita , Sarmiento Salcedo Magdalena 
Published: February 2025

La contratación pública es uno de los instrumentos que, por excelencia, permiten materializar de forma real los fines esenciales del Estado consagrados en el artículo 2 de la Constitución Política, y actualmente, también cumplir con los Objetivos de Desarrollo Sostenible de la Agenda 2030. Las Compras Públicas Sostenibles con el medio ambiente o aquellas que incluyen criterios ambientales encuentran relación directa con el objetivo número 12 relacionado con la producción y consumo sostenibles. Si bien, las estadísticas más recientes (2022) sobre el cumplimiento de la Agenda 2030 en Colombia no incluyen cifras directamente relacionadas con la contribución de las Compras Públicas Sostenibles con el medio ambiente, como instrumento para lograr avances en este objetivo, es evidente que el marco regulatorio colombiano sobre esta materia es coherente, en gran medida, con el contenido de este objetivo y algunas de sus metas conexas, y por tanto, puede ser un instrumento ideal para alcanzarlo satisfactoriamente en el 2030.
А. Ф. ЛОСЕВ И СВЯТОЙ МАКСИМ ИСПОВЕДНИК В СРАВНИТЕЛЬНОЙ ПАРАДИГМЕ ЦЕРКОВНОГО ОПЫТА АСКЕЗЫ
Authors: Келеберда Нина Григорьевна 
Published: February 2025

Цель исследования заключается в сопоставительном рассмотрении мировоззренческих аспектов А. Ф. Лосева и святого Максима Исповедника сквозь призму аскетического опыта.
Методы исследования. Исследование базируется на общенаучных методах дедукции, индукции, дифференциации и интеграции, а также включает сравнительный и биографический методы.
Результат исследования. Тема аскетизма в монашестве в сравнительной парадигме опыта А. Ф. Лосева и святого Максима Исповедника выступает своего рода индикатором «православности», а жизнеописание является основой для философских, теологических и богословских выводов. Автор приходит к заключению, что аскетизм как видимая общинная практика церкви, проявляющаяся во внутреннем благочестии, не выражена в характере мышления А. Ф. Лосева, что особенно очевидно в сравнении с принципами мышления Максима Исповедника — признанного отца церкви, и, следовательно, философские построения А. Ф. Лосева нельзя относить к опыту церкви.
Перспективы исследования. Результаты исследования являются дискуссионными и представляют интерес для философов, теологов и богословов, поскольку проблема интерпретации мировоззренческих установок А. Ф. Лосева как православных по преимуществу составляет опасную тенденцию для церковного сознания.
СКУЛШУТИНГ В СИСТЕМЕ СЕТЕВОГО ОБЩЕСТВА: СТРАТЕГИИ ИЗУЧЕНИЯ
Authors: Сергодеева Елена Александровна , Барсукова Татьяна Ивановна , Ляпунова Татьяна Георгиевна 
Published: February 2025

Целью исследования является разработка методологических оснований исследования скулшутинга как деструктивного явления сетевого общества, выявления детерминирующих его факторов и функциональных последствий распространения.
Методологическую базу исследования представляют основные положения акторно-сетевого подхода. Для анализа скулшутинга как разновидности девиантного поведения и социальной патологии применялись процедуры структурно-функционального и социально-психологического подхода. Общая социальная оценка скулшутинга была произведена на основании социальных теорий сетевого общества и массовой коммуникации.
Результаты исследования. Показано, что скулшутинг как деструктивная девиация в дискурсе сетевого общества проявляется в различных сферах человеческой жизнедеятельности и требует во время анализа в первую очередь опору на особенности природы нашей объективной действительности. Он может пониматься как социальная патология, как деструктивная форма субкультуры, как инфоповод для стимуляции неопределённости и социальной раздражительности за счёт бесконечной репродукции образов, которые всё сильнее отдаляются от обыденной повседневности. Для самих скулшутеров их активность свидетельствует о желании совершения противоправных действий ради привлечения внимания.
Проведенный анализ позволяет предположить, что воздействие скулшутинга способно проникать в уязвимые сферы человеческой деятельности латентным способом, скрывая те инициирующие его факторы, которым не уделяется достаточное внимание.
Перспективы исследования заключаются в возможностях разработки комплексной методологии исследования скулшутинга и формирования мер его профилактики и предотвращения в сетевой среде современного общества.
Проблемы идентичности беременных женщин: обзор отечественных и зарубежных исследований
Authors: Колиниченко Ирина Александровна , Никулина Светлана Анатольевна 
Published: February 2025

<p>Представлен анализ феномена идентичности женщин в период беременности. Выявлено два основных вектора исследований проблемы материнства в современной психологии: материнство как взаимодействие с ребенком и материнство как аспект личности женщины.</p><p>Обосновывается необходимость продолжения работы по объединению самостоятельных направлений изучения материнства и идентичности для уточнения условий, при которых происходят принятие и оценка желательности материнской роли для адекватной психологической помощи женщинам с трудностями в прохождении этого процесса.</p><p>Проанализированы представления о материнстве в структуре идентичности в зависимости от теоретических представлений зарубежных психологических школ и фокусировки на детерминантах его развития. В числе значимых признаются соотношение биологического и социального в формировании поведения матери, кризисный момент развития идентичности беременной женщины, прекращения ее единоличного существования при возникновении диады «мать — дитя». </p><p>Проводится анализ восприятия беременными транзитивности своего статуса в отличие от материнства, подвижности осознаваемых статусов. Аргументируется наличие текущего, проходящего варианта идентичности беременных, отличающегося от восприятия идентичности матери (стабильного и устойчивого). </p>
Literature review on zirconia post system
Authors: Mishra Preeti , Raj Shalya , Nikhil Vineeta 
Published: February 2025

Cast metal post and core systems have been reliably used for decades due to their excellent physical properties. However, the increasing demand for aesthetically pleasing and biocompatible restorations has spurred the development of tooth-colored post and core systems. Among these, zirconia post systems have gained popularity, offering a solution that combines strength with enhanced esthetics. The translucency of zirconia allows for seamless integration with all-ceramic crowns, maintaining a natural appearance and meeting patient expectations for visually appealing restorations.In light of the growing interest in zirconia ceramic post systems, numerous in vitro studies have been conducted over the past 15 years to evaluate their performance. These studies have examined critical aspects such as retention, fracture resistance, and aesthetic advantages. Zirconia posts are celebrated for their ability to improve esthetics while providing sufficient strength and long-term durability.Nevertheless, zirconia posts are not without limitations. Issues like achieving proper cementation and optimal adhesion remain active areas of research and clinical focus. This review article aims to consolidate existing data on zirconia posts, highlighting their retention, fracture resistance, aesthetic benefits, challenges, and cementation techniques to aid clinicians in their effective application.