bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gender Features of Renin-Angiotensin-Aldosterone System in the Light of the Pandemic COVID-19
Authors: Павлова О.С. 
Published: March 2022

Пандемия COVID-19 является чрезвычайной ситуацией в большинстве стран мира, и определение наиболее уязвимых групп населения для снижения смертности – приоритетная задача в области здравоохранения. Полученные данные свидетельствуют о том, что вероятность смерти мужчин после постановки диагноза COVID-19 на 50% выше, чем у женщин. В литературном обзоре содержится анализ публикаций, посвященных гендерным особенностям функционирования ренин-ангиотензин-альдостероновой системы, которые могут влиять на различную предрасположенность к коронавирусной инфекции COVID-19. В статье поднимаются вопросы лечения блокаторами ренин-ангиотензин-альдостероновой системы при сердечнососудистых заболеваниях у пациентов с коронавирусной инфекцией, вызванной SARS-COV-2. Применение ингибиторов ангиотензинпревращающего фермента и блокаторов ангиотензина II способствует восстановлению баланса вазоконстрикторных и вазодилатирующих факторов ренин-ангиотензин-альдостероновой системы с последующими противовоспалительным, антиоксидантными, антифибротическими эффектами, что может оказывать протективное влияние на течение и исходы коронавирусной инфекции COVID-19.
The COVID-19 pandemic is an exceptional situation in most countries of the world. Identifying the most vulnerable populations to reduce mortality is a public health priority. The obtained data indicate that the probability of death in men in the diagnosis of COVID-19 is 50% higher than in women. The review contains the analysis of publications on the gender characteristics of the renin-angiotensin-aldosterone system functioning, which can influence different predisposition to coronavirus infection COVID-19. The article raises the issues of treatment with the renin- angiotensin-aldosterone blockers in patients with cardiovascular diseases and coronavirus infection caused by SARS-COV-2. The use of angiotensin-converting enzyme inhibitors and angiotensin II blockers helps to restore the balance of the vasoconstrictor and vasodilating factors of the renin-angiotensin-aldosterone system with subsequent anti-inflammatory, antioxidant,antifibrotic effects, which can have a protective effect on the progress and outcome of coronavirus infection COVID-19.
Treatment of Atopic Dermatitis in Children: Focus on Prevention and Restoration of the Epidermal Barrier
Authors: Титова Н.Д. 
Published: March 2022

В статье представлены эволюция взглядов на этиопатогенез заболевания и изменившиеся подходы к лечению детей с атопическим дерматитом. Изложены основные механизмы этиопатогенеза атопического дерматита, влияние липидзамещающей терапии на воспаление и восстановление функции эпидермиса, даны рекомендации по уходу за кожей детей с атопическим дерматитом, правила выбора и особенности применения эмоллиентов у детей. Интересны исследования о влиянии состава микробиома кожи на становление барьерной функции кожи и формирование иммунного равновесия, представлен современный взгляд на профилактическое и терапевтическое применение пробиотических штаммов.
The article presents the evolution of views on the etiopathogenesis of the disease and the changed approaches to the treatment of children with atopic dermatitis. The main mechanisms of etiopathogenesis of atopic dermatitis, the effect of lipid replacement therapy on inflammation and restoration of the epidermis function are described, recommendations for skin care for children with atopic dermatitis, the rules for the selection and features of the use of emollients in children are given. Interesting studies of the effect of the composition of the skin microbiome on the formation of the barrier function of the skin and the formation of immune balance, present a modern look at the preventive and therapeutic use of probiotic.
Chelated Forms of Minerals – a Step into the Future…
Authors: Воронов Г.Г. 
Published: March 2022

В статье представлена обзорная информация из литературных источников, посвященная актуальной проблеме обеспечения человеческого организма минеральными веществами, или минералами, особенно с точки зрения возможностей экзогенной коррекции их дефицитных состояний с помощью пищевых продуктов и биологически активных добавок. Особое внимание уделено вопросам усвояемости минералов, что во многом определяется физико-химическими особенностями минералов и их способностями образовывать комплексы с неорганическими и органическими лигандами. Уделено внимание вопросам хелатирования минералов с аминокислотами, что позволяет повысить их системную биодоступность в процессе всасывания в желудочно-кишечном тракте и снизить процент нежелательных реакций при их применении в качестве пищевых добавок. Отдельно рассмотрены биологическое значение для организма одного из органических лигандов, в частности глицина, его биотехнологическая роль в процессах получения хелатных форм минералов.
The article provides overview information from literature devoted to the urgent problem of providing the human body with mineral substances or minerals, especially from the point of view of the possibilities of exogenous correction of their deficiency states using food products and biologically active additives. Particular attention is paid to the digestibility of minerals, which is largely determined by the physicochemical characteristics of minerals and their ability to form complexes with inorganic and organic ligands. Attention is paid to the chelation of minerals with amino acids, which makes it possible to increase their systemic bioavailability during absorption in the gastrointestinal tract and reducethepercentageofundesirablereactionswhenusedasfoodadditives.Thebiologicalsignificance for the organism of one of the organic ligands, in particular glycine, and its biotechnological role in the processes of obtaining chelated forms of minerals are considered separately.
novo curso de graduação na Universidade Federal de Minas Gerais
Authors: Soza Isabelle Cornelio Balbi , Bernardino Elidéa Lúcia Almeida 
Published: March 2022

O presente artigo aborda o curso de graduação presencial em Letras-Libras Licenciatura na Universidade Federal de Minas Gerais (UFMG) e como se iniciou este curso, desde as disciplinas de Libras ofertadas como eletivas até seu vestibular no segundo semestre do ano de 2019. Trata-se de um curso e um tema atuais, a inclusão dos surdos dentro dos espaços acadêmicos, com foco na inclusão da UFMG tanto na modalidade presencial quanto no Ensino Remoto Emergencial- ERE e as metodologias de ensino para a comunidade surda. Procura-se apresentar as perspectivas do aluno e do professor em um tempo tão único, quais as dificuldades e novas perspectivas para este novo curso acadêmico presencial em um momento de pandemia, com o ERE.

Palavras-chave: Letras-Libras. UFMG. Ensino Remoto Emergencial.
PERLINDUNGAN PELAKU USAHA MIKRO, KECIL DAN MENENGAH MELALUI POLA KEMITRAAN, KEAGENAN DAN DISTRIBUSI DALAM PERSPEKTIF HUKUM PERJANJIAN
Authors: Sudjana U. 
Published: March 2022

Pelaku UMKM dalam pola kemitraan tidak memiliki posisi tawar karena klausula perjanjiannya ditentukan sepihak oleh prinsipal, sehingga pelaku UMKM dirugikan. Karena itu, kajian ini bertujuan menentukan pelindungan terhadap agen dan distributor sebagai pelaku UMKM melalui pola kemitraan dalam perspektif hukum perjanjian. Metode penelitian dilakukan dengan pendekatan yuridis normatif dengan tahap penelitian studi kepustakaan menggunakan analisis data normatif kualitatif. Hasil penelitian menunjukan bahwa karakteristik dan hubungan hukum dalam perjanjian keagenan dan distribusi termasuk diantara perjanjian sewa menyewa dan perjanjian jual beli, sehingga ketentuan umum KUHPerdata dapat diberlakukan terhadap kedua pola kemitraan tersebut selain ketentuan yang bersifat khusus. Pelaku UMKM dalam pola kemitraan keagenan dan distribusi dalam perspektif hukum perjanjian secara normatif telah mendapat pelindungan karena setiap perusahaan perdagangan nasional yang membuat perjanjian dengan prinsipal barang atau jasa produksi luar negeri atau dalam negeri sebagai agen dan distributor wajib didaftarkan di Kementerian Perdagangan untuk memperoleh Surat Tanda Pendaftaran.
Edukacja w czasie pandemii z perspektywy studentów uczelni muzycznej
Authors: Walecka Aleksandra 
Published: March 2022

CEL NAUKOWY: Celem podjętych rozważań jest opisanie, w jaki sposób studenci uczelni muzycznej spostrzegają swoją codzienną edukację w czasach pandemii wirusa SARS-CoV-2.
PROBLEM I METODY BADAWCZE: Problem badawczy został sformułowany w postaci pytania: Jak pandemia oddziałuje na działania podejmowane przez studentów uczelni muzycznej oraz co zmieniło się w ich postrzeganiu czasu i przestrzeni? Badania przeprowadzono przy wykorzystaniu autobiograficznego wywiadu narracyjnego.
PROCES WYWODU: Rozważania nad podjętą problematyką rozpoczęto od analizy kategorii życia codziennego w nawiązaniu do czasu i przestrzeni. Opisano również, w jaki sposób zaburzenie co[1]dzienności może oddziaływać na człowieka.
WYNIKI ANALIZY NAUKOWEJ: Analiza zebranego materiału ukazała, że pandemia w dużym stopniu ograniczyła dotychczasową działalność artystyczną zarówno w obszarze edukacji akademickiej, jak dodatkowej aktywności wykraczającej poza plan studiów. Wprowadzone ograniczenia oraz brak konfrontacji z publicznością przyczynił się do tego, że nie mają odpowiednich warunków do rozwoju własnych umiejętności. Edukacja zdalna jest dla nich utrudnieniem ze względu na problemy techniczne, ale łączy się także z dużym obciążeniem psychicznym. Zmianie uległ również ich sposób postrzegania przestrzeni i czasu studiów.
WNIOSKI, INNOWACJE, REKOMENDACJE: Czas pandemii dla badanych studentów wiążę się z zawiedzionymi oczekiwaniami, koniecznością rezygnacji z podejmowanych wcześniej aktywności, a także niepewnością, czy będą w odpowiedni sposób przygotowani do podjęcia przyszłej pracy zawodowej.
FAKTOR KRIMINOGEN TINDAK PIDANA PERIKANAN DI PERAIRAN MALUKU UTARA
Authors: Utami Arum Oktavia Tri , Rachmawati Yundha , Fitriono Riska Andi 
Published: March 2022

Provinsi Maluku merupakan provinsi dengan mayoritas wilayahnya adalah perairan, berdasarkan penelitian presentase besar wilayah perairannya adalah 94 %. Perairan yang luas ditambah dengan kekayaan flora dan fauna di dalamnya tentu menjadi incaran bagi wilayah lain untuk melakukan eksploitasi. Hal yang menjadi keresahan selama dekade terakhir adalah maraknya Illegal Fishing di dalam masyarakat. Hal ini mengakibatkan rendahnya pemasukan dari masyarakat. Untuk menanggulangi masalah tersebut, pemerintah dengan cekatan mengeluarkan Undang-Undang Nomor 45 Tahun 2009 perubahan atas Undang-Undang Nomor 31 Tahun 2004 tentang Perikanan (selanjutnya disingkat UUP) yang mengatur mengenai regulasi yang berkaitan dengan larangan kategori penangkapan ikan, secara kewajiban serta saksi yang diterima. Penelitian dilakukan dengan metode studi kasus untuk mengetahui mengapa dan bagaimana suatu fenomena bisa terjadi. Penelitian metode ini tergolong jenis penelitian kualitatif yang reaksi penelitiannya berbentuk penelitian deskriptif naratif. Ditemukan sebab-sebab tindakan pidana perikanan berasal dari dalam diri pelaku berupa keinginan untuk mendapatkan keuntungan secepat mungkin, faktor dari luar berupa kondisi ekonomi yang tidak memadai.
ANALISIS KUALITAS PELAYANAN RAWAT INAP PADA MASA PANDEMI COVID-19 DI RUMAH SAKIT CIREMAI KOTA CIREBON
Authors: Erna Erna , Ramadhani Irfan 
Published: March 2022

Perkembangan teknologi yang pesat dan adanya persaingan rumah sakit dituntut untuk memberikan dan meningkatkan pelayanannya. Pasien akan merasa puas apabila pelayanan kesehatan yang diperoleh sesuai dengan harapaanya, maka sudah selayaknya Rumah Sakit Ciremai Kota Cirebon memperhatikan kualitas pelayanan guna meningkatkan kepuasaan pasien. Penelitian ini bertujuan untuk mengetahui bagaimana kualitas pelayanan terhadap kepuasan pasien rawat inap pada masa pandemi covid-19 di rumah sakit ciremai kota Cirebon.
Penelitian ini menggunakan metode penelitian deskriptif analisis. Pengambilan sampel dilakukan menggunakan teknik accidental sampling melalui penyebaran angket/kuesioner dengan jumlah responden sebanyak 100 orang. Teknik analisis data menggunakan analisis deskriptif.
Hasil analisis data terkait variabel Kualitas Pelayanan (X) yang memperoleh nilai skor total sebesar 4.821 atau 88% dengan kategori sangat baik . Selain itu, variabel Kepuasaan (Y) juga memperoleh nilai skor total sebesar 3.474 atau 87% dengan kategori sangat setuju.
Quando as regras da morada geraram revolta: uma reinterpretação da emergência das Ligas Camponesas (1955-1964)
Authors: Guandalini Genaro Eduardo , Alves Gomes Ramonildes 
Published: March 2022

This article discusses how the relationship between large landowners and those who lived on these properties changed, observing how the values ​​of the morada were resignified by residents during the mobilization of the Ligas Camponesas in Paraíba to determine traces of continuity and discontinuity between symbols, the repertoire of the movement, and the morality of these actors. We analyze this process from the relationship between morality and revolt, focusing on the question of how the foreiros, who were most responsible for disseminating the moral rules of the morada, were mobilized the most in the Ligas. This is accomplished by hermeneutic analysis of second-hand oral reports of narratives by participants in the movement.elocation-id: e2230106Received: 10.13.2021 • Accepted: 03.03.2022 • Published: 03.30.2022Original article / Blind peer review / Open access
Prevalencia de burnout en enfermeras de nefrología tras un año de pandemia por COVID-19
Authors: Terns-Campius Laura , Pedreira-Robles Guillermo 
Published: March 2022

Introducción: La prevalencia de la enfermedad renal crónica, así como la complejidad de su manejo terapéutico, hace que las enfermeras de nefrología sean susceptibles a sufrir síndrome de Burnout. En este escenario, ha aparecido la pandemia por COVID-19. Esta nueva situación puede potenciar la aparición de Burnout entre las enfermeras nefrológicas. Objetivo: Describir la prevalencia del Síndrome de Burnout, entre las enfermeras de un servicio de nefrología de un hospital terciario. Método:Estudio observacional, descriptivo, transversal y unicéntrico. La recogida de datos se efectuó mediante un cuestionario ad-hoc con preguntas sociodemográficas y laborales. Se administró el cuestionario validado “Maslach Burnout Inventory Human Services Survey (MBI-HSS)”, compuesto de preguntas sobre sentimientos y actitudes de profesionales hacia pacientes y compañeros de trabajo. Resultados: Se incluyó a 28 enfermeras, correspondiendo al 71,79% de la población a estudio, con una media de 18,00±12,17 años de experiencia. 11 (39,28%) tuvieron COVID-19. 24 (85,71%) estaban vacunadas. 18 (64,29%) no recibieron formación específica sobre el SARS-CoV2. 13 (46,43%) enfermeras tenían miedo de transmitir la COVID-19 a su entorno y 5 (17,90%) tenían miedo a contagiarse. 19 (67,86%) se sentían mal anímicamente.Los resultados del MBI-HSS destacaron a 15 (58,57%) enfermeras con al menos dos de las tres esferas del Síndrome de Burnout afectadas. Conclusiones: Las enfermeras presentan un riesgo real de SdB en el contexto actual descrito y la implementación de programas de prevención y tratamiento sería lo apropiado según la literatura de referencia. La esfera con mayor afectación reportada es la de la realización personal.
Synthesis of combinational circuits by means of bi-decomposition of Boolean functions
Authors: Pottosin Yu. V. 
Published: March 2022

O b j e c t i v e s . The problem of synthesis of combinational circuits in the basis of two-input gates is considered. Those gates are AND, OR, NAND and NOR. The objective of the paper is to investigate the possibilities of application of bi-decomposition of Boolean functions to the synthesis of combinational circuits.M e t h o d s . The method for bi-decomposition is reduced to the search in a graph for a weighted two-block cover with complete bipartite subgraphs (bi-cliques).R e s u l t s . The initial Boolean function is given as two ternary matrices, one of which represents the domain of Boolean space where the function has the value 1, and the other is the domain of Boolean space where the function has the value 0. The orthogonality graph of rows of ternary matrices representing the given function is considered. The method for two-bi-clique covering the orthogonality graph of rows of ternary matrices is described. Every bi-clique in the obtained cover is assigned in a certain way with а set of variables that are the arguments of the function. This set is the weight of the bi-clique. Each of those bi-cliques defines a Boolean function whose arguments are the variables assigned to it. The functions obtained in such a way constitute the required decomposition.Co n c l u s i o n . The process of synthesis of a combinational circuit consists of a successive application of bi-decomposition to obtained functions. The suggested method allows obtaining the circuits with short delay.
Article Continued - Outcomes of the Southern African Lepidoptera Conservation Assessment (SALCA)
Authors: Mecenero Silvia , Edge David A. , Staude Hermann S. , Coetzer Bennie H. , Coetzer André J. , Raimondo Domitilla C. , Williams Mark C. , Armstrong Adrian J. , Ball Jonathan B. , Bode Justin D. , Cockburn Kevin N.A. , Dobson Chris M. , Dobson Jeremy C.H. , Henning Graham A. , Morton Andrew S. , Pringle Ernest L. , Rautenbach Fanie , Selb Harald E.T. , Van Der Colff Dewidine , Woodhall Steve E. 
Published: March 2022

Issue consists of one article divided into downloadable PDFS.
The Southern African Lepidoptera Conservation Assessment (SALCA) was a collaborative venture between the Lepidopterists’ Society of Africa (LepSoc Africa), the Brenton Blue Trust (BBT) and the South African National Biodiversity Institute (SANBI), and formed part of the National Biodiversity Assessment (NBA). SALCA was founded on the importance of Lepidoptera both ecologically and as biodiversity indicators and the proven expertise of the participants during the Southern African Butterfly Conservation Assessment (SABCA). The main outcomes of the SALCA project are presented and discussed here.The SALCA tool, a custom-designed interactive distribution database, enabled high quality data to be derived so that accurate conservation assessments could be produced in accordance with IUCN methodology. The Red Lists of SALCA and SABCA facilitated the first opportunity to calculate the Red List Index (RLI) for South African butterflies during the period from 2012–2018. Other metrics required for the NBA included protection level and threats analyses. A further outcome was the critical habitat mapping for butterflies, which formed part of a screening tool implemented by SANBI, to ensure that land use changes did not cause any further loss of butterfly biodiversity.A comprehensive distribution database was developed for South African moths, enabling data to be analysed so that moth species potentially threatened could be short-listed for further investigation.
Error analysis of the jeep start 1 students’ second language production
Authors: Usop Juharto Lidasan 
Published: March 2022

The study aimed to examine the errors of the JEEP Start 1 students in second language production in relation to their language background at Cotabato City State Polytechnic College during the school year 2016-2017. This study used the descriptive – comparative design. The students’ language spoken at home and the type of school attended in basic education shall be correlated with the errors of JEEP Start 1 students in second language production. The researcher utilized the oral reading test and communicative speaki1ng test. The data were collected from 25 pre-selected third Year College students of CCSPC enrolled in the College of Education. The study covered error analysis of the JEEP Start 1 students’ second language production. This study was solely conducted at Cotabato City State Polytechnic College which is located at Sinsuat Avenue, Cotabato City. It is also included the significant relationship of the identified skills. The subjects of the study were oriented by the researcher about the nature of activity. It is concluded that the degree of errors of the JEEP Start 1 students in phonology and syntax can’t be predicted by their gender and language spoken at home.
EFFECTS OF COMMONLY AVAILABLE WHITENING CREAMS ON THE HAIR FOLLICLES OF GUINEA PIG SKIN
Authors: Saqib Sadia , Nadia Haq  
Published: March 2022

BACKGROUND: The trend of lightening the skin is becoming a serious problem. Depigmentation creams are widely available as nonprescription cosmetic preparations in many local markets and shops.
OBJCETIVES: To determine the effects of over the counter available skin whitening creams on the hair follicles of guinea pig skin. To highlight the significance of awareness in general population about the use of non-prescription skin lightening creams.
METHODS: Sample size of 48 adult, guinea pigs were used in this experiment. The animals were randomly divided into four groups. Group I (control group) this group was applied with no cream and group II, III and IV (experimental groups) all were applied with skin whitening creams A, B and C respectively once every day, six days a week for four and eight weeks duration. The skin specimens were examined at histological level.
RESULTS: Microscopic examination after 4 weeks duration showed variable degree of increased size of hair follicles from 104.8µm in group l to the maximum of 130.5µm in group lll. The effects were exaggerated after eight weeks duration.

CONCLUSION: The use of skin lightening creams caused varying degrees of side effects so damage the skin.
A Feminist Stylistic Pursuit: Investigation of Sidhwa’s The Bride (1990) to Decode Gendered Language-Use
Authors: Muhmmad Shakil Ur Rehman  , Suleman Nazia , Mohammad Shafi  
Published: March 2022

By applying Sara Mill’s Feminist Stylistics (1995), the study aims to unfold the implicit gender stereotyping in Sidhwa’s The Bride(1990). The fictional work of Sidhwa is investigated to problematize how gender representation strengthens the proposition of Sara Mills (1995) that men are described linguistically according to their names, titles, profession and physical appearance that lead to make them superior in comparison to women. By implying the feminist stylistics as a “toolkit” (Mills, 1995, p.2), it is to highlight a particular type of sexist language-use in the novel that paints a hegemonic ideology for gender disparity. The key objective of the study is to question through the language use as is recommended by the undertaken framework - word, phrase/sentence, discourse to demonstrate how physical appearances, hair style, title-addresses, names and clothing etc. play an overriding role to uphold gender disparity. The ethnic and religious identification of people are categorized also on their specific dresses and get-ups to manifest disparity based on socio-cultural norms. The findings of the present research recommend that socio-cultural conventional gender taboos are manufactured through a specific language-use to serve masculine’s interests as a sign of authority and dominance over women. The culturally gendered language portrayed in the novel is meant to discriminate against women, if they resist it, they are treated as ‘other’ and ‘unnatural’ by male dominated society.