bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Adsorption and Aging Process of Cadmium and Chromium in Soil Micro-aggregates
Authors: Wen Lijia , Liao Bing , Liu Guo , Tang Haoran , Yang Shuang , Wen Huan , Qin Jie 
Published: January 2022

Abstract
The particle size and components of soil aggregates have played important roles in the migration and transformation of heavy metals. The present study focused on the adsorption behavior and aging characteristics of cadmium (Cd) and chromium (Cr) in various granular aggregates and soil components, which were studied by analyzing the adsorption isotherm, adsorption kinetics, and heavy metal speciation distribution. The results showed that, compared with other aggregates, clay aggregates (0–0.002 mm) had the strongest adsorption effect on Cd and Cr and that there was no significant positive correlation between the adsorption amount and the particle size of aggregates for Cd and Cr. In general, the influence of three components on Cd was organic matter &gt; amorphous iron &gt; free iron oxide, and the influence on Cr was free iron oxide &gt; amorphous iron &gt; organic matter. The adsorption isotherm showed that the correlation coefficient of the Langmuir model (R2) was higher than that of the Freundlich model (R2), indicating that the adsorption of Cd and Cr by soil aggregates can be well described by the Langmuir model with monolayer adsorption behavior. Kinetic adsorption studies showed that quasi-first-order kinetics and quasi-second-order kinetics were more consistent with the actual adsorption amounts of Cd and Cr in soil aggregates, respectively. At the same time, the forms of Cd and Cr gradually transformed from unstable to stable after entering the soil. After 60 days, Cd was mainly oxidized, and residual, and Cr was mainly reduced and residual. These results provide a theoretical basis for assessing the environmental risks of Cd and Cr and providing prevention and treatment methods. Environ Toxicol Chem 2022;41:975–990. © 2022 SETAC
Site- and Individual-Level Contaminations Affect Infection Prevalence of an Emerging Infectious Disease of Amphibians
Authors: Smalling Kelly L. , Mosher Brittany A. , Iwanowicz Luke R. , Loftin Keith A. , Boehlke Adam , Hladik Michelle L. , Muletz-Wolz Carly R. , Córtes-Rodríguez Nandadevi , Femmer Robin , Campbell Grant Evan H. 
Published: January 2022

Abstract
Emerging infectious disease outbreaks are one of multiple stressors responsible for amphibian declines globally. In the northeastern United States, ranaviral diseases are prevalent in amphibians and other ectothermic species, but there is still uncertainty as to whether their presence is leading to population-level effects. Further, there is also uncertainty surrounding the potential interactions among disease infection prevalence in free-ranging animals and habitat degradation (co-occurrence of chemical stressors). The present study was designed to provide field-based estimates of the relationship between amphibian disease and chemical stressors. We visited 40 wetlands across three protected areas, estimated the prevalence of ranavirus among populations of larval wood frogs and spotted salamanders, and assessed chemical and biological stressors in wetland habitats and larval amphibians using a suite of selected bioassays, screening tools, and chemical analyses. Ranavirus was detected on larval amphibians from each protected area with an estimated occupancy ranging from 0.27 to 0.55. Considerable variation in ranavirus occupancy was also observed within and among each protected area. Of the stressors evaluated, ranavirus prevalence was strongly and positively related to concentrations of metalloestrogens (metals with the potential to bind to estrogen receptors) and total metals in wetland sediments and weakly and negatively related to total pesticide concentrations in larval amphibians. These results can be used by land managers to refine habitat assessments to include such environmental factors with the potential to influence disease susceptibility. Environ Toxicol Chem 2022;41:781–791. © 2022 SETAC. This article has been contributed to by US Government employees and their work is in the public domain in the USA.
Sediment Remediation Using Activated Carbon: Effects of Sorbent Particle Size and Resuspension on Sequestration of Metals and Organic Contaminants
Authors: Rämö Robert , Bonaglia Stefano , Nybom Inna , Kreutzer Anne , Witt Gesine , Sobek Anna , Gunnarsson Jonas S. 
Published: January 2022

Abstract
Thin-layer capping using activated carbon has been described as a cost-effective in situ sediment remediation method for organic contaminants. We compared the capping efficiency of powdered activated carbon (PAC) against granular activated carbon (GAC) using contaminated sediment from Oskarshamn harbor, Sweden. The effects of resuspension on contaminant retention and cap integrity were also studied. Intact sediment cores were collected from the outer harbor and brought to the laboratory. Three thin-layer caps, consisting of PAC or GAC mixed with clay or clay only, were added to the sediment surface. Resuspension was created using a motor-driven paddle to simulate propeller wash from ship traffic. Passive samplers were placed in the sediment and in the water column to measure the sediment-to-water release of polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), and metals. Our results show that a thin-layer cap with PAC reduced sediment-to-water fluxes of PCBs by 57% under static conditions and 91% under resuspension. Thin-layer capping with GAC was less effective than PAC but reduced fluxes of high–molecular weight PAHs. Thin-layer capping with activated carbon was less effective at retaining metals, except for Cd, the release of which was significantly reduced by PAC. Resuspension generally decreased water concentrations of dissolved cationic metals, perhaps because of sorption to suspended sediment particles. Sediment resuspension in treatments without capping increased fluxes of PCBs with log octanol–water partitioning coefficient (KOW) &gt; 7 and PAHs with log KOW of 5–6, but resuspension reduced PCB and PAH fluxes through the PAC thin-layer cap. Overall, PAC performed better than GAC, but adverse effects on the benthic community and transport of PAC to nontarget areas are drawbacks that favor the use of GAC. Environ Toxicol Chem 2022;41:1096–1110. © 2022 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.
Effects of Separate and Combined Exposure of Cadmium and Lead on the Endochondral Ossification in Bufo gargarizans
Authors: Chen Aixia , Deng Hongzhang , Song Xiuling , Liu Xiaoli , Chai Lihong 
Published: January 2022

Abstract
Cadmium (Cd) and lead (Pb) are ubiquitous in aquatic environments and most studies have examined the potential effects of Cd or Pb alone on aquatic organisms. In the present study, chronic effects of Cd and Pb, alone and in combination, on Bufo gargarizans were investigated by exposing embryos to these contaminants throughout metamorphosis. Significant reductions in body mass and snout-to-vent length were observed in B. gargarizans at Gosner stage 42 (Gs 42) and Gs 46 exposed to a Cd/Pb mixture. Single and combined exposure with Cd and Pb induced histological alterations of the thyroid gland characterized by reduced colloid area and thickness of epithelial cells. There was a significant decrease in the maximum jump distance of froglets exposed to Cd alone and the Cd/Pb mixture, and the jumping capacity showed a positive correlation with hind limb length and tibia/fibula. Moreover, single metals and their mixture induced reduction of endochondral bone formation in B. gargarizans. Transcriptomic and real-time quantitative polymerase chain reaction results showed that genes involved in skeletal ossification (TRα, TRβ, Dio2, Dio3, MMP9, MMP13, Runx1, Runx2, and Runx3) were transcriptionally dysregulated by Cd and Pb exposure alone or in combination. Our results suggested that despite the low concentration tested, the Cd/Pb mixture induced more severe impacts on B. gargarizans. In addition, the Cd/Pb mixture might reduce chances of survival for B. gargarizans froglets by decreasing size at metamorphosis, impaired skeletal ossification, and reduction in jumping ability, which might result from dysregulation of genes involved in thyroid hormone action and endochondral ossification. The findings obtained could add a new dimension to understanding of the mechanisms underpinning skeletal ossification response to heavy metals in amphibians. Environ Toxicol Chem 2022;41:1228–1245. © 2022 SETAC
Consumers' acceptance of the first novel insect food approved in the European Union: Predictors of yellow mealworm chips consumption
Authors: Petrescu‐Mag Ruxandra Malina , Rastegari Kopaei Hamid , Petrescu Dacinia Crina 
Published: January 2022

AbstractClimate and environmental‐related challenges are high on the agenda of the European Union (EU). One priority is to redesign the existing food system into a more sustainable one, where the link between healthy people and a balanced environment is considered. The EU bets on the role of insect farming in supporting the transition toward healthier and future‐proof diets. Following this orientation, we investigated consumers' attitude toward yellow mealworm chips (YMC) and identified the predictors of YMC consumption. The causal relationships between constructs were explored using the structural equation modeling (SEM) based on partial least squares (PLS) using SmartPLS software. The perceived lower environmental impact of YMC compared to meat was the most appreciated characteristic of YMC. The study identified five predictors of YMC consumption, among which the perceived characteristics of YMC have the strongest influence on the consumption probability. Against the expectations of the authors, disgust with the accidental encounter of insects in foods did not influence the probability of eating YMC. Age was another predictor of YMC consumption. It is known that food preferences and eating behaviors are mainly developed during childhood and tend to manifest in adult life. Consequently, it can be inferred that acceptance and preference for insect‐based foods (IBF) should be stimulated from early childhood. Finally, practical implications are advanced as possible solutions to overcome the obstacles toward YMC consumption.
Nasopharyngeal cancer: Incidence and prognosis of human papillomavirus and Epstein–Barr virus association at a single North American institution
Authors: Wu Shannon S. , Chen Bonnie , Fleming Christopher W. , Shah Akeesha A. , Griffith Christopher C. , Domb Chaim , Reddy Chandana A. , Campbell Shauna R. , Woody Neil M. , Lamarre Eric D. , Lorenz Robert R. , Prendes Brandon L. , Scharpf Joseph , Schwartzman Larissa , Geiger Jessica L. , Koyfman Shlomo A. , Ku Jamie A. 
Published: January 2022

AbstractBackgroundThe prognostication of Epstein–Barr virus (EBV) and human papillomavirus (HPV) status in nasopharyngeal cancer (NPC) is unclear.MethodsThis retrospective study analyzed NPC from 2000 to 2019.ResultsSeventy‐eight patients were included: 43 EBV+, 12 HPV+, 23 EBV−/HPV−, and 0 EBV+/HPV+. All p16+ tumors were also positive for HPV‐CISH. Baseline characteristics were not different between groups except age, N‐classification, and Karnofsky Performance Scale (KPS) (p < 0.05). For EBV+, HPV+, and EBV−/HPV− respectively, 3‐year overall survival (OS) was 89.9%, 69.8%, and 52.5% (p = 0.006). EBV−/HPV− status was significantly associated with worse OS but not freedom from progression (FFP) on univariate analysis, and did not remain a significant predictor of OS after adjusting for KPS, age, and group stage.ConclusionsEBV+ NPC tumors were seen in younger, healthier patients than HPV+ and EBV− tumors, and there were no cases of coinfection. The association of viral status with OS was insignificant after adjusting for KPS and age.
Untangling harvest‐streamflow responses in foothills conifer forests: Nexus of teleconnections, summer‐dominated precipitation, and storage
Authors: Goodbrand Amy , Anderson Axel , Devito Kevin , Silins Uldis 
Published: January 2022

AbstractThis study re‐evaluated data from the historical Tri‐Creeks Experimental Watershed (1967–1988) in Alberta, Canada to address the initial question of forest harvest effects on streamflow and investigate the potential influence of teleconnections, summer‐dominated precipitation, and watershed storage on runoff generation. Tri‐Creeks has deep (up to 21 m) glacial deposits underlain by folded and faulted sedimentary bedrock with considerable potential for subsurface water storage. Timing of the conifer forest harvest experiment in two sub‐watersheds (>50% harvested) and one reference occurred near the 1976–77 Pacific Decadal Oscillation (PDO) phase change that led to less snowfall, but little difference in annual precipitation or runoff between phases after harvest. Established statistical and hydrological modelling methods that used regression techniques of observed and simulated streamflow to separately analyse sub‐watersheds did not detect change in average daily or annual runoff due to harvest. The interannual hydroclimatic variability influenced by the climate shift, attenuation of summer precipitation by the drier antecedent conditions in the warm period following harvest, and large potential for subsurface water storage contributed to shifts in runoff and uncertain detection of streamflow response. However, a hydrological modelling approach using calibrated parameters separately in the pre‐ and post‐harvest periods indicate significant change in rainfall‐generated peak runoff events and summer runoff following harvest, which was not detected in the reference watershed. Model calibration required less soil storage capacity in the treated watersheds in the post‐harvest period compared to the reference likely due to reduced transpiration that increased the likelihood of storm runoff during larger summer rainfall events. Within the context of streamflow responses to harvest in conifer dominated forest landscapes with seasonal snow cover, this study illustrates how complexity of climate variability and interaction with watershed storage and continental summer‐dominated precipitation may confound and mask the interpretation of harvest effects in paired‐watershed studies.
Cancer risk and mortality after solid organ transplantation: A population‐based 30‐year cohort study in Finland
Authors: Friman Terhi Kristiina , Jäämaa‐Holmberg Salla , Åberg Fredrik , Helanterä Ilkka , Halme Maija , Pentikäinen Markku O. , Nordin Arno , Lemström Karl B. , Jahnukainen Timo , Räty Riikka , Salmela Birgitta 
Published: January 2022

AbstractCancer is a significant cause of morbidity and mortality after solid organ transplantation (SOT) and related to lifelong immunosuppression. This retrospective registry study assessed for the first time in Finland population‐based cancer risk and cancer mortality after all SOTs (lung and childhood transplantations included) as standardized incidence ratios (SIRs) and standardized mortality ratios (SMRs). Data from transplant registries were linked with the data of Finnish Cancer Registry and Statistics Finland. We followed 6548 consecutive first SOT recipients from 1 January 1987 to 31 December 2016 translating to 66 741 person‐years (median follow‐up time 8.9 years [interquartile range 4.0‐15.1]). In total, 2096 cancers were found in 1483 patients (23% of all patients). Majority of cancers (53%) were nonmelanoma skin cancers (NMSCs). The overall SIR was 3.6 (95% confidence interval [CI]: 3.5‐3.8) and the SIR excluding NMSCs was 2.2 (95% CI: 2.0‐2.3). SIR for all cancers was highest for heart (5.0) and lowest for liver (2.7) recipients. Most common cancer types after NMSCs were non‐Hodgkin lymphoma (NHL), SIR 9.9 (95% CI: 8.5‐11.4) and kidney cancer, SIR 7.3 (95% CI: 6.0‐8.8). Cancer‐related deaths were 17% (n = 408) of all deaths after first month post transplantation. SMR for all cancers was 2.5 (95% CI: 2.2‐2.7) and for NHL 13.6 (95% CI: 10.7‐16.8). Notably, overall SIR for cancer was lower in later period (2000‐2016), 3.0 (95% CI: 2.8‐3.2), than in earlier period (1987‐1999), 4.3 (95% CI: 4.0‐4.5), P < .001. Decrease in cancer incidence was temporally associated with major changes in immunosuppression in the 2000s.
Dairy product consumption and risk of cancer: A short report from the NutriNet‐Santé prospective cohort study
Authors: Deschasaux‐Tanguy Mélanie , Barrubés Piñol Laura , Sellem Laury , Debras Charlotte , Srour Bernard , Chazelas Eloi , Wendeu‐Foyet Gaëlle , Hercberg Serge , Galan Pilar , Kesse‐Guyot Emmanuelle , Julia Chantal , Babio Sánchez Nancy Elvira , Salas Salvadó Jordi , Touvier Mathilde 
Published: January 2022

AbstractThe impact of dairy product consumption for long‐term health remains unclear, in particular regarding their involvement in cancer etiology for frequent locations like breast or prostate. Besides, little is known about potentially different effects of dairy product subtypes. Our objective was therefore to evaluate the associations between dairy product consumption (total and subtypes) and cancer risk. A total of 101 279 participants from the French NutriNet‐Santé cohort study were included (78.7% women; mean [SD] age = 42.2 [14.5] years). Dairy product consumption was assessed using validated web‐based 24‐hour dietary records. Multiadjusted Cox models were computed. After a median [interquartile range] follow‐up time of 5.9 [2.7‐8.3] years, we documented 2503 incident cancer cases (783 breast, 323 prostate and 182 colorectal cancers). Total dairy product consumption was not significantly associated with cancer. However, the consumption of “fromage blanc” (a French type of quark/cottage cheese) was associated with an increased risk of cancer overall (HR for 1 serving increment [95% CI] = 1.11 [1.01‐1.21]; P‐trend = .03) and of colorectal cancer (HR = 1.39 [1.09‐1.77]; P‐trend < .01). Besides, sugary dairy dessert consumption was directly associated with colorectal cancer risk (HR for 1 serving increment = 1.58 [1.01‐2.46]; P‐trend = .046]. No association was observed between the consumption of dairy products or sugary dairy desserts and the risk of prostate and breast cancers. In our study, the consumption of dairy products was not associated with the risk of overall, colorectal, breast or prostate cancers. The consumption of “fromage blanc” and sugary dairy desserts were associated to an increased risk of colorectal cancer, but this warrants further investigations.
Identification of polypharmacological anticancerous molecules against Aurora kinase family of proteins
Authors: Gupta Deepali , Kumar Mukesh , Singh Mandeep , Salman Mohd , Das Uddipan , Kaur Punit 
Published: January 2022

AbstractThe Human Aurora Kinase (AURK) protein family is the key player of cell cycle events including spindle assembly, kinetochore formation, chromosomal segregation, centrosome separation, microtubule dynamics, and cytokinesis. Their aberrant expression has been extensively linked with chromosomal instability in addition to derangement of multiple tumor suppressors and oncoprotein regulated pathways. Therefore, the AURK family of kinases is a promising target for the treatment of various types of cancer. Over the past few decades, several potential inhibitors of AURK proteins have been identified and have reached various phases of clinical trials. But very few molecules have currently crossed the safety criteria due to their various toxic side effects. In the present study, we have adopted a computational polypharmacological strategy and identified four novel molecules that can target all three AURKs. These molecules were further investigated for their binding stabilities at the ATP binding pocket using molecular dynamics based simulation studies. The molecules selected adopting a multipronged computational approach can be considered as potential AURKs inhibitors for cancer therapeutics.
The effects of precursor concentration and morphology on photoluminescence behavior of Tb2O3 phosphors
Authors: Unal Fatma 
Published: January 2022

AbstractTerbium oxide (Tb2O3) phosphors were prepared the using sol‐precipitation method with the use of different precursor concentrations. The X‐ray diffraction (XRD) patterns showed C‐type body‐centered cubic phase, space group Ia‐3, and the crystallite size values were found in the range of 19.45–32.34 nm depending on the solution composition and calcination temperature. As the crystallinity increased, the defects in the structure decreased, that is, the dislocation density decreased. Under the excitation at 325 nm, although all the Tb2O3 phosphors emitted a single peak around 544 nm (5D4‐7F5 transition) in PL spectra, when the peak was enlarged, the presence of additional peaks shifted to the red/blue region was also observed. The color chromaticity coordinates showed that it exhibited different tones of emission from light yellow to green depending on the precursor concentration and calcination temperature. With increasing the precursor concentration, nucleation rate increased and the particle shape changed from nearly spherical to rod‐like. They may be promising for laser devices and display applications due to their strong green emission.
Ultrastructural adaptation of the oropharyngeal cavity of the Eurasian common moorhen (Gallinula chloropus chloropus): Specific adaptive dietary implications
Authors: Bassuoni Naglaa F. , Abumandour Mohamed M. A. , Morsy Kareem , Hanafy Basma G. 
Published: January 2022

AbstractThe present investigation represents the first morphological description of the oropharyngeal cavity of Eurasian common moorhen. Nine oropharyngeal cavities were examined grossly and by stereomicroscope and scanning electron microscopic (SEM) observations. The tongue had a rounded apex with multiple acicular processes on its rostral and lateral borders. The dorsal lingual surface of the apex and body had a median sulcus. The papillary crest carried four caudally directed triangular conical papillae on its median part and four triangular conical papillae on each lateral part. The filiform papillary system; small papillae on apex and long papillae on the rostral part of the body while broad papillae on the caudal part of the body. The lingual root had a special appearance by presence of three areas: mucosal fossa, two lateral ridges, and rhomboidal elevated central part. The caudal border of the mound carried heart‐shaped pharyngeal papillae that possessed three papillary rows. The palate had a median palatine ridge rostrally that surrounded by two lateral palatine ridges. The choanae had two equal parts: rostral tapering and wide caudal. The rostral tapering choanal part was surrounded by two longitudinal rows of caudally directed conical papillae, one on each side. There was a single transverse row of conical papillae on each side of the caudal part of the rostral tapering choanal part. The caudal wide choanal part did not encircle by any papillae. Our conclusion exhibited unique structural and functional specifications of the oropharyngeal cavity with the tongue that evident with nutritional behavior.