bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Systematic Review and Meta-Analysis of the Prevalence of Methamphetamine Abuse in Iranian High School Students
Authors: Sayyah Mehdi ,   Education Development Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Shirbandi Kiarash ,   Systematic Review and Meta-analysis Expert Group (SRMEG), Universal Scientific Education and Research Network (USERN), Tehran, Iran, Javanmardi Fatemeh ,   Department of Biostatistics, Health Sciences School, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Rahim Fakher ,   Health Research Institute, Thalassemia and Hemoglobinopathies Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran,   Fakher Rahim, Health Research Institute, Thalassemia and Hemoglobinopathies Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran, Telephone: +98-61-33367571, Fax: +98-61-33367571, E-mail: Bioinfo2003@gmail.com
Published: November 2022

Background and Aim
Abuse of drugs such as methamphetamine is one of the most important problems in high-school children and adolescents according to the World Health Organization (WHO), which has mentioned it as a concerning event in the world. Therefore, the purpose of this study was to estimate the prevalence of methamphetamine abuse in Iranian students using the meta-analysis method on studies conducted in Iran.

Materials and Methods
To select the studies, a systematic search was performed on leading databases, including ISI web of science, PubMed, Scopus, Embase, PsycINFO and PROSPERO with no language limits from their inception to 31 Jan 2018. Furthermore, local databases, including SID, Magiran, and IRANDOC were searched systematically using both Persian and English languages from their inception to 31 Jan 2018.

Results
We found a total of 828 potentially relevant studies, of which 30 met our criteria, and 7 articles (7452 students, 3063 females and 4389 males) were included. The pooled prevalence of methamphetamine use in Iranian students was 0.016% (95% CI: 0.06-0.041, P=0.00). The heterogeneity was low (I2 =44.41, d.f = 6), which shows that about 94.41 of the total observed variance was true variance between the studies.

Conclusion
Although the prevalence of methamphetamine in high-school students is lower than in other drugs, a growing pattern in Iranian high-school students in recent years is a serious warning to authorities and families. Increasing families and students’ knowledge about the harmful effects of this drug can be an effective approach to reducing its prevalence in young people, especially high-school students.
The Effect of Life Skills Training on the Self-Management of Patients with Multiple Sclerosis
Authors: Hemmatpoor Behzad ,   Clinical Research Development Center, Kermanshah University of Medical Sciences, Kermanshah, Iran, Gholami ALI ,   Clinical Research Development Center, Kermanshah University of Medical Sciences, Kermanshah, Iran, Parnian Shima ,   Department of Medical-Surgical Nursing, Iran University of Medical Sciences, Tehran, Iran,   Dr. Shima Parnian, Iran University of Medical Sciences, Medical-Surgical Nursing, Tehran, The Islamic Republic of Iran, E-mail: shimaparnian1991@gmail.com, Seyedoshohadaee Mahnaz ,   Department of Medical-Surgical Nursing, Iran University of Medical Sciences, Tehran, Iran
Published: November 2022

Background
Training sessions are the most common framework used to provide self-management for patients with multiple sclerosis

Objective
This study was conducted to determine the effect of life skills training on the self-management of patients with multiple sclerosis. Findings showed that life skills training had a significant effect on the overall self-management score; thus, self-management of patients increased after training life skills (F = 25.1821, P <0.01).

Materials and Methods
This semi-experimental study was conducted on 80 subjects with MS in the MS Society in Tehran (Iran) in 2016. The experimental group received four one-hour sessions of life skills training. The control group received routine care. Patients of both groups filled MS self-management (MSSM) scales at baseline and a month after the last training session. Independent t-test was used to compare findings between the two groups; pairwise t-test was used to compare results before and after the test. Covariance test was used to present the research results and data was analyzed by using SPSS21.

Findings
Mean and standard deviation of age were 32.22±8.88 and 33.02±10.34 in the control and experimental groups, respectively.

Results
Comparison of total self-management showed a significant difference between the control and experimental groups after receiving life skill training (P<0.01). Moreover, there was a significant difference in the mean of total self-management in the experimental group before and after the intervention; self-management increased after intervention (p-value<0.001).

Conclusion
This study showed the positive effect of life skills training because its main goal is to prepare and help patients solve problems and deal with difficulties resulting from the disease. Therefore, life skill training is suggested for patients suffering from MS.
Prenatal Genetic Testing for Dopa-Responsive Dystonia – Clinical Judgment in the Context of Next Generation Sequencing
Authors: Nedelea Florina ,   Filantropia Clinical Hospital, Bucharest, Romania,   Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, Veduta Alina ,   Filantropia Clinical Hospital, Bucharest, Romania,   Alina Veduta, Filantropia Clinical Hospital, 11 – 13, Ion Mihalache Blvd Postal Code 011171, Bucharest, Romania E-mail: alina.veduta@gmail.com Phone: +40745636052, Duta Simona ,   Filantropia Clinical Hospital, Bucharest, Romania, Vayna Ana-Maria ,   Filantropia Clinical Hospital, Bucharest, Romania, Panaitescu Anca ,   Filantropia Clinical Hospital, Bucharest, Romania,   Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, Peltecu Gheorghe ,   Filantropia Clinical Hospital, Bucharest, Romania,   Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, Duba Hans-Christoph ,   Kepler Universitätsklinikum Linz, Austria
Published: November 2022

We present a family in which the first child was diagnosed with dopa-responsive dystonia based on biochemical findings only. Dopa-responsive dystonia is a severe heterogeneous genetic disease. The possibly involved genes are GCH1 and TH.
In their second pregnancy, the parents came for genetic counseling and prenatal diagnosis late, at 12 weeks of gestation. Genetic testing in the affected child was performed, but the results were difficult to interpret. The identified mutations were classified as VOUS – variants of unknown clinical significance. Although possibly causative, a homozygous variant in the TH gene was not reported before in children with dopa-responsive dystonia. Due to limited time, establishing the fetal prognosis was challenging.
Our report emphasizes the importance of a multidisciplinary approach in the context of new diagnostic techniques, such as Next Generation Sequencing. We illustrate the fact that behind any laboratory result remains sophisticated clinical judgment. We also describe a previously not reported variant of the TH gene in a child with severe, early-onset dystonia.
التوزيع الجغرافي لاستعمالات الأرض الزراعية في ناحية دجلة لسنة 2019
Authors: Al-Saeed Arif Abdul Razzaq , Muhammad Hakam Dhiab 
Published: November 2022

تناولت الدراسة التوزيع الجغرافي لاستعمالات الأرض الزراعية في منطقة الدراسة (ناحية دجلة ) لسنة 2019 على وفق المقاطعات الزراعية , إذ من خلال الدراسة تبين أن هنالك تباينا في المساحات المزروعة بالمحاصيل الزراعية بين المقاطعات , ويعود ذلك إلى التباين أيضاً في مساحة المقاطعات الزراعية وتباين ظروفها الطبيعية والبشرية والحياتية المؤثرة فيها , إذ شغلت محاصيل الحبوب لاسيما القمح المساحة الأوسع من بين بقية المحاصيل الاخرى والبالغة (101625 دونما ) ثم جاءت بعدها محاصيل الخضراوات والعلف والبستنة , أما ما يخص الثروة الحيوانية فقد شهدت تباينا في تربيتها بين المقاطعات , والذي اتضح من خلال الدراسة ان تربية الاغنام تنشط في المقاطعات الغربية من منطقة الدراسة والتي تتسم بانبساط الارض وسعة المساحة وصلاحيتها لرعي الحيوانات لاسيما في فصل سقوط الامطار , كما شهدت تربية الجاموس اقتصار تربيته على ثلاث مقاطعات وذلك لتوافر بعض الظروف الملائمة له .
إذ توصي الدراسة بالعمل على وجود سياسة داعمة من قبل الدولة تجاه المزارعين ومربي الثروة الحيوانية من اجل النهوض بالواقع الزراعي من خلال الدعم المادي والمعنوي , كذلك التوجه الى حماية المنتوج الزراعي من خلال منع استيراد المحاصيل الزراعية في اوقات توافرها محلياً , وذلك من اجل تأمين الغذاء للسكان وزيادة المساحة المزروعة بالمحاصيل الغذائية و المنتجات الحيوانية من لحوم و البان .
Structural effect on the charge transfer and on the internal reorganization energy: Computational study
Authors: Jabha Mohamed , El Alaoui Abdelah , Jarid Abdellah , Mabrouk El Houssine 
Published: November 2022

The effects of addition of thiophene, bridged phenyl-thiophene, thia-tetra-azacyclopenta-naphthalene, benzo-bis-thiadiazole, and pyrido(3,4-b)pyrazine to 9-(4-octyloxyphenyl)-2,7-divinylcabazole on the internal reorganization energies, electronic affinity, and ionization potential were studied using density functional theory (DFT). These compounds are characterized by their charge exchange potentials (donor-acceptor), which can be applied in energy conversion devices such as photovoltaic cells. The so-called internal reorganization concerns, above all, the positions of holes and points of high electron density on the molecular skeleton. Thus, valuable information is provided by the knowledge of the structure, the length of the desired oligomer and the nature of the radicals attached to the oligomer. Considering the available data, 2,7-divnyl-carbazole (CrV-H) is the basic oligomer to carry out this theoretical study by extending the choice of ligands and length order to other oligomers while setting charge mobility as the major objective. The λ+ of all the oligomers studied was lower than their λ– except for the CrV-BBT oligomer, indicating a lower hole transfer cost than electron transfer cost with changes in molecular geometry during this�process.
Pengenalan Digital Marketing untuk Petani Milenial dalam Memasarkan Produk Hasil Pertanian di Desa Patok Kalianda
Authors: Setiawan Jaka 
Published: November 2022

Pada era digital saat ini perkembangan teknologi informasi yang ditandai dengan maraknya Smartphone sebagai media komunikasi digital yang beredar serta perkembangannya sangat pesat berpengaruh bagi masyarakat dalam mendukung kegiatan bisnis baik besar maupun kecil di seluruh sektor salah satunya sektor pertanian. Ada keperhatian besar terkait dengan kondisi para petani saat ini. Produk pertanian berlimpah diiringi harga bahan pokok yang tinggi namun harga jual hasil pertanian yang rendah dikarenakan petani sebagai produsen untuk menjual hasil pertanian melalui panjangnya rantai distribusi dan ketergantungan petani pada tengkulak. Melihat kondisi tersebut maka diperlukan upaya untuk meningkatkan harga tawar petani dengan cara menghubungkan petani langsung kepada konsumen. Salah satu cara yakni dengan memanfaatkan teknologi digital marketing atau pemasaran online kepada para petani. Dengan adanya kegiatan ini petani diharapkan lebih memahami pentingnya penggunaan digital marketing seperti social media, website, dan lain sebagainya untuk mendukung pemasaran produk pertanian. Metode pengabdian ini dilakukan dengan penyuluhan, praktik penggunaan social media dan diskusi. Kegiatan pengabdian masyarakat ini diberikan kepada pengurus anggota ikatan tani kota kalianda yang beranggotakan petani muda yang aktif dalam mengelola pertanian dan memahami penggunaan smartphone. Diharapkan dengan kegiatan ini para petani di desa patok kalianda bisa meningkatkan keterampilan dalam memasarkan produk pertanian secara luas dan menjadi seorang petani yang milenial.
HUBUNGAN KEAKTIFAN KELUARGA DALAM KEGIATAN POSYANDU DENGAN STATUS GIZI BALITA DI KELURAHAN KEBUN SIKOLOS
Authors: Hendayani Weni Lidya , Amalia Rosa Fitri 
Published: November 2022

Data Depkes tercatat jumlah anak balita yang terkena gizi buruk melonjak dari 1,8 juta (2005) menjadi 2,3 juta anak (2006). Dalam kurun waktu itu, lebih dari lima juta balita terkena gizi kurang, bahkan (10%) berakhir dengan kematian. Tujuan penelitian ini adalah untuk mengetahui hubungan keaktifan keluarga dalam kegiatan posyandu dengan status gizi balita di wilayah kerja Puskesmas Kebun Sikolos tahun 2016. Penelitian ini menggunakan metode deskriptif analitik dengan pendekatan cross sectional study. Penelitian dilakukan di wilayah kerja Puskesmas Kebun Sikolos Padang Panjang tahun 2016. Populasi dalam penelitian ini berjumlah 1.319 orang. Teknik pengambilan sampel secara purposive sampling, dengan sampel sebanyak 111 orang. Pengolahan data dilakukan secara komputerisasi menggunakan program SPSS (Statistical Product and Service Solutions)dengan analisa univariat dan bivariat, uji statistik yang dipakai adalah chi-square. Hasil analisa univariat menunjukkan bahwa lebih dari separuh keluarga aktif dalam kegiatan posyandu (53,2%), lebih dari separuh status gizi anak baik (66,7%). Pada analisa bivariat p = value 0,893 berarti tidak terdapat hubungan yang signitif antara keaktifan keluarga dengan status gizi balita. Maka dari itu hendaknya keluarga tetap menjaga gizi anaknya supaya anaknya tidak terkena gizi buruk yaitu dengan cara selalu aktif dalam kegiatan posyandu yang telah tersedia sehingga angka kematian gizi buruk bisa menurun.
MANAJEMEN GENERAL ANESTESI PADA PASIEN SPLENOMEGALI
Authors: Selvia Dea , Wahyuni Ari 
Published: November 2022

Pendahuluan : Splenomegali merupakan suatu kondisi adanya pembesaran limpa atau lien yang diukur berdasarkan ukuran atau beratnya. Lien merupakan organ tubuh yang memiliki peran penting dalam proses imunologis dan hematopoiesis. Fungsi utama limpa termasuk dalam proses fagositosis eritrosit abnormal, pembersihan terhadap mikroorganisme dan antigen serta melakukan sintesis terhadap imunoglobulin G (IgG). Lien juga berperan dalam proses sintesis peptida sistem imun properdin dan tuftsin. Sekitar sepertiga dari trombosit yang bersirkulasi disimpan di limpa. Berat normal limpa orang dewasa adalah 70 g hingga 200 g, berat limpa 400 g sampai 500 g menunjukkan splenomegaly, berat limpa lebih besar dari 1000 g definitif splenomegali masif. Pembahasan : Tata laksana yang tepat pada splenomegali adalah dengan melakukan tindakan operatif yaitu splenektomi. Splenektomi dapat dilakukan melalui prosedur laparotomy dengan general anestesi. Kesimpulan: Tindakan splenektomi dengan general anestesi pada pasien menjadi topik yang menarik dengan memperhatikan kondisi kesehatan setiap individu dalam merespon pemberian tindakan anestesi yang diberikan. Pada tulisan ini akan dibahas mengenai penyebab splenomegali, evaluasi, dan manajemen anestesi pada tindakan splenektomi.Kata kunci : Anestesi, Splenomegali, Splenektomi
PROFILE KEBERADAAN EXTENDED SPECTRUM BETA LACTAMASE BERDASARKAN JENIS BAKTERI, JENIS SPESIMEN DAN SUMBER RUANGAN
Authors: Lestari Diah - 
Published: November 2022

Pengobatan penyakit infeksi umumnya dengan pemberian antibiotik. Antibiotik yang dijual bebas dan penggunaan secara tidak tepat menimbulkan resistensi antibiotik. Golongan β-laktam adalah antibiotik yang sering digunakan dan adanya resistensi menyebabkan bakteri terus berkembang biak dan mengakibatkan munculnya enzim Extended spectrum beta-lactamase (ESBL) yang dihasilkan oleh kuman famili Enterobacteriaceae, terutama Klebsiella pneumoniae dan Escherichia coli. Tujuan penelitian untuk mengetahui profile keberadaan extended spectrum beta lactamase (ESBL) berdasarkan jenis bakteri, jenis specimen dan sumber ruangan di RSUD dr. Chasbullah Abdulmadjid Kota Bekasi. Metode penelitian dilakukan berdasarkan analitik deskriptif cross sectional menggunakan data sekunder hasil pemeriksaan kultur mikroorganisme dan resistensi antibiotik. Sampel penelitian adalah spesimen sputum, urin, pus, darah dan cairan tubuh lain berjumlah 98 isolat E. coli dan K. pneumoniae. Hasil penelitian dari 98 isolat E. coli dan K. pneumoniae ditemukan ESBL positif sebanyak 56,1%. Spesies E. coli ESBL positif ditemukan pada spesimen pus dan urin sebanyak 33,3% dan K. pneumoniae ESBL positif pada spesimen pus sebanyak 48,0%. Isolat E. coli ESBL positif banyak berasal dari ruang ICU dan ruang inap bedah (Tulip) 20,0% dan isolat K. pneumoniae ESBL positif sebanyak 12,0% berasal dari rujukan luar. Isolat E. coli ESBL menunjukkan sensitifitas tinggi terhadap antibiotik ertapenem, meropenem, amikacin dan tigecycline (100%). Isolat K. pneumoniae ESBL menunjukkan sensitifitas yang baik terhadap meropenem (96%), ertapenem (88%), amikacin (88%) dan tigecycline (84%). Kata kunci : ESBL, resistensi antibiotik, β-laktam, isolat E. coli, isolat K. pneumoniae.
PERBANDINGKAN KADAR HEMOGLOBIN SEBELUM DAN SESUDAH MENGKONSUMSI TABLET Fe PADA IBU HAMIL TRIMESTER I DI PUSKESMAS PATAMUAN
Authors: Susanti Devi , Niken Niken , Yusuf Rahmi Novita 
Published: November 2022

Hampir separuh atau sebanyak 48,9 persen ibu hamil di Indonesia mengalami anemia. Ibu hamil yang kekurangan cadangan zat besi dapat menyebabkan anemia defisiensi zat besi. Jumlah Fe yang dikonsumsi oleh ibu hamil selama kehamilan ada hubungannya dengan angka kejadian anemia dalam kehamilan, dan peningkatan Hb setelah mengkonsumsi tablet Fe. Penelitian ini bertujuan untuk mengetahui perbandingan kadar hemoglobin sebelum dan setelah mengkonsumsi tablet fe pada ibu hamil trimester I di Puskesmas Patamuan. Jenis penelitian quasy experiment. Penelitian ini telah dilakukan di Puskesmas Patamuan dan waktu penelitian dilaksanakan pada bulan Maret 2021. Populasi dalam penelitian ini adalah ibu hamil trimester I dengan sampel penelitian 20 orang sampel. Analisa data secara univariat dan bivariat dengan memakai uji independent t test. Hasil dari penelitian menunjukkan rerata kadar hemoglobin sebelum mengkonsumsi tablet Fe adalah 10.9 g/dL. Rerata kadar hemoglobin setelah mengkonsumsi tablet Fe adalah 11.58 g/dL. Terdapat perbedaan antara kadar hemoglobin sebelum dan setelah mengkonsumsi tablet Fe (p value 0.004 < 0,05) Kesimpulan dari penelitian menunjukkan dengan pemberian tablet Fe pada ibu hamil dapat memberikan pengaruh terhadap peningkatan kadar Hb pada ibu hamil yang mengalami anemiaKata Kunci : Jumlah Limfosit,Tenaga Kesehatan ,Vaksin COVID-19
Spatial analysis of globally detected volcanic lightning from the June 2019 eruption of Raikoke volcano, Kuril Islands
Authors: Smith Cassandra M. , Van Eaton Alexa R. , Schneider David J. , Mastin Larry , Matoza Robin S. , McKee Kathleen , Maher Sean 
Published: November 2022

The 21–22 June 2019 eruption of Raikoke volcano, Russia, provided an opportunity to explore how spatial trends in volcanic lightning locations provide insights into pulsatory eruption dynamics. Using satellite-derived plume heights, we examine the development of lightning detected by Vaisala’s Global Lightning Dataset (GLD360) from eleven, closely spaced eruptive pulses. Results from one-dimensional plume modeling show that the eruptive pulses with maximum heights 9–16.5 km above sea level were capable of producing ice in the upper troposphere, which contributed variably to electrification and volcanic lightning. A key finding is that lightning locations not only followed the main dispersal direction of these ash plumes, but also tracked a lower-level cloud derived from pyroclastic density currents. We show a positive relationship between umbrella cloud expansion and the area over which lightning occurs (the ‘lightning footprint’). These observations suggest useful metrics to characterize ongoing eruptive activity in near real-time.
Yeni Bir Tür Olarak Sürükleyici Gazetecilik: Metaverse Gazeteciliğine Doğru
Authors: YETKİN Barış 
Published: November 2022

İnsanı insan yapan en temel niteliklerden biri teknolojiyi kullanabilme becerisi ise diğer de iletişim kurma ve dolayısıyla bilgiyi geleceğe taşıyabilmedir. Teknolojik gelişmeler yazılımsal ve donanımsal olarak hızla devam etmektedir. Kurum ve kuruluşların, Web 3.0 ile birlikte bireyin iletişim içine girme, bilgiyi arşivleme-paylaşabilme ve toplumsallaşma biçimleri daha önceki dönemlerden çok daha dramatik biçimde dönüşmektedir.
Bu makale, teknolojinin gelişimine bağlı olarak yeni gazetecilik türleri varsayımından hareket etmektedir. Medya her zaman teknolojinin en sadık takipçileri olagelmiştir. Matbaanın icadı ile başlayan medya kuruluşlarının teknolojiyi yakın takibi, gazete, televizyon, radyo ve yeni medya uzantılarında devam ederken kaçınılmaz olarak, veri gazeteciliği, robot gazetecilik, drone gazeteciliği, artırılmış gerçeklik gazeteciliği, blokzincir gazeteciliği vb. yeni gazetecilik türlerini ve pratiklerini ortaya çıkarmaktadır. Yeni türlerden biri de sürükleyici gazeteciliktir. Teknolojik gelişmeler, sanal gerçeklik (VR) ve artırılmış gerçeklik (AR) teknolojilerini kullanan bu gazetecilik türünün kalıcı olmayacağı, dolayısıyla kullanıcıları, gazetecileri ve medya kuruluşlarını yeni bir mecraya hazırladığını ortaya çıkarmaktır.
Türkiye’de sürükleyici gazetecilik ile ilgili yapılmış çalışmalar sınırlı sayıdadır. Bu makale, sürükleyici gazeteciliği tanımlama girişimidir. Betimsel analiz yöntemiyle, sürükleyici gazeteciliğin ne olduğu, niye ortaya çıktığı ve nasıl uygulandığı anlaşılmaya çalışılmaktadır; dolayısıyla yeni bir mecra olan Metaverse’a uyumlaşma sağlayabilecek bir gazetecilik türü olup olmadığı sorgulanabilecektir. Böylece bu çalışmanın gelecek araştırmalar için işlevsel olacağı umut edilmektedir.
A Comparison of outcome between Transabdominal Preperitoneal (TAPP) and Lichtenstein operation for primary inguinal hernia repair – An institutional study
Authors: Rayamajhi Bikash Bahadur , Basukala Sunil , Thapa Narayan , Ayer Dhirendra , Karki Saurav , Basukala Bikram 
Published: November 2022

Introduction: Inguinal hernia repairs are one of the most common operations in general surgery. Apart from the classical open repairs, minimally invasive approaches are increasingly preferred to manage groin hernia repair. However, the optimal surgical approach still remains controversial.
Methods: This is a prospective observational study done in Shree Birendra Hospital, a 750- bedded tertiary care military hospital located in Kathmandu from July 2021 to December 2021. A total of 120 patients operated for inguinal hernia by either open Lichtenstein repair or Transabdominal Preperitoneal (TAPP) in the department of surgery were included in this study.
Results: The mean age of patients between open Lichtenstein repair and TAPP was 59.3 (22-79) and 63.4 (27-70) years respectively. The majority of patients were male among both the groups constituting of more than 95%. The mean intraoperative duration among the two groups was 44.12±7.23 minutes and 77.43±8.77minutes, respectively (p=0.021). The mean postoperative pain was less in TAPP procedure compared to open procedure (p=0.037). The mean duration of the postoperative hospital stay was 2± 1.12 and 1±0.79 respectively. At the three-month evaluation, there were four cases of recurrence of which one of them underwent open procedure while three underwent TAPP procedure.
Conclusion: Both the open Lichtenstein repair and the TAPP procedures are safe and effective in the repair of primary inguinal hernia. In a view of postoperative pain, seroma formation and length of hospital stay TAPP procedure has been found superior to open procedure in our study.