bluuebunny/crossref_metadata_2025_split huggingface dataset:
Russia
Authors: Skaridov Alexander S 
Published: February 2025

Abstract
The Russian style of rulemaking has formed over many centuries, passing through several formative stages and historical experiences of Christianity and cultural contributions associated with a multi-ethnic State. The system has its inception in Roman law, combined with traditional values transmitted through history and shaped by the definitive role that the Orthodox faith played in the life of the Russian person. Soon after the advent of a Russian fleet of notoriety in the early 1700s, the first systemized regulations on maritime transportation of goods were imported from Germany and Holland. The legal culture of eighteenth-century Russia was influenced by the infatuation of the tsar’s entire court with all things Western. However, the individualism inherent in the Western European consciousness was in stark collision with the Russian concept of sobornost, or unity within the organic fellowship of the Orthodox Church, as opposed to the individualism in the Protestant ethic and the juridical authority in the Catholic tradition. This idea incorporates a sense that decisions are taken by conducting a general ‘people’s survey’ or plebiscite prior to making important regulatory decisions. A ‘healthy pragmatism’ shaped the Soviet culture of legal objectivism in relations with the Western countries throughout the nascent era of Soviet Russia and continues to this day. Hardly anything can be considered a more genuine part of the Russian culture than its ability to endure in challenging times.
East Asia
Authors: Lee Seokwoo 
Published: February 2025

Abstract
As maritime societies flourished along the shores of East Asia, they cultivated a profound connection with the seas, shaping their collective identity and influencing their approach to governance. The cultural heritage of East Asia, encompassing philosophical beliefs, ancient maritime traditions, and profound reverence for the natural world, has left an indelible mark on the development and evolution of the law of the sea. The law of the sea, a pivotal framework governing the rights and responsibilities of nations over oceanic spaces, has emerged as a reflection of diverse cultural narratives and historical experiences. Within this context, East Asia stands as an exceptional case study, where cultural values and traditions have intricately intertwined with modern legal principles, crafting a unique maritime legal landscape. Embodied in the cultural fabric of East Asia lies Confucianism, a philosophical system emphasizing respect for authority and the pursuit of harmony within hierarchical relationships. The East Asian approach to the law of the sea is shaped by a combination of national interests, political constraints, and cultural influences. Economic, security, and territorial concerns drive national interests, while domestic and international political factors play a significant role. Additionally, the region’s historical cultural interactions contribute to its distinct maritime practices. Understanding these multifaceted dynamics is crucial to grasping the East Asian perspective on the law of the sea.
South America
Authors: Teresa Infante María 
Published: February 2025

Abstract
Latin American cultural influences are generally of Western origin with deep elements of Native American and African culture. The colonial experience and legacy of intervention by European states and the United States have influenced the perceptions of security and independence that are expressed in economic and military norms towards the sea. Since World War II, significant developments in Latin America have participated in the global trajectory of the law of the sea. The concerted efforts by the Latin American countries to develop law of the sea institutions and to establish them in practice prompted a search for negotiations at a global scale. Latin American countries are fully immersed in the technical and legal processes of delineating extended continental shelves. On the other hand, Latin American countries and Caribbean states have renewed the historic dialogue over the extent of ocean sovereignty and sovereign rights, adding in emerging notions or models, such as shared or common spaces. These views also reflect the interconnection between the environmental agenda and the law of the sea. Moreover, Latin American nations have aimed to join other states and regions around a conception of global oceans governance. This shift towards a global approach is underscored by the enthusiasm with which Latin American and Caribbean states embraced the negotiations on the 2023 High Seas Biodiversity Treaty.
Quebec French Version of the Hayling Sentence Completion Test: Error Scoring Guidelines, Normative Data for Adults and the Elderly and Validation Study in Mild Cognitive Impairment and Alzheimer’s Disease
Authors: Macoir Joël , Lapierre Véronick , Brouillard Marie-Michelle , Verreault Phylicia , Landry Mariane , Hudon Carol 
Published: February 2025

Abstract

Introduction
Deficits in inhibition have been associated with various clinical conditions, including neurodegenerative diseases. The Hayling Sentence Completion Test (HSCT) is an assessment tool commonly used in clinical settings to measure verbal initiation and prepotent verbal response inhibition. Although it is used by numerous clinical and research groups in Quebec, normative data for the HSCT are not yet available for French-Quebec speakers.

Objectives
The aims of this study were to provide error scoring guidelines and normative data in the adult population of French Quebec for the HSCT-QC (Study 1) and to determine its known-group discriminant validity (Study 2).

Results
The results of Study 1, based on a sample of 214 healthy individuals aged 50 to 89, indicated that age significantly affected test performance, while educational level and sex did not. As no transformations were able to normalize the score distribution, percentile ranks for HSCT-QC performance were calculated solely based on age. Results from Study 2 demonstrated that the HSCT-QC effectively distinguishes the performance of healthy participants from those with mild cognitive impairment or Alzheimer’s disease.

Conclusion
Norms and psychometric data for the HSCT-QC will be highly beneficial for assessing inhibitory control in French-speaking adults in Quebec, Canada.
iDOMO: identification of drug combinations via multi-set operations for treating diseases
Authors: Zhou Xianxiao , Wu Ling , Wang Minghui , Wu Guojun , Zhang Bin 
Published: February 2025

Abstract
Combination therapy has become increasingly important for treating complex diseases which often involve multiple pathways and targets. However, experimental screening of drug combinations is costly and time-consuming. The availability of large-scale transcriptomic datasets (e.g. CMap and LINCS) from in vitro drug treatment experiments makes it possible to computationally predict drug combinations with synergistic effects. Towards this end, we developed a computational approach, termed Identification of Drug Combinations via Multi-Set Operations (iDOMO), to predict drug synergy based on multi-set operations of drug and disease gene signatures. iDOMO quantifies the synergistic effect of a pair of drugs by taking into account the combination’s beneficial and detrimental effects on treating a disease. We evaluated iDOMO, in a DREAM Challenge dataset with the matched, pre- and post-treatment gene expression data and cell viability information. We further evaluated the performance of iDOMO by concordance index and Spearman correlation on predicting the Highest Single Agency (HSA) synergy scores for four most common cancer types in two large-scale drug combination databases, showing that iDOMO significantly outperformed two existing popular drug combination approaches including the Therapeutic Score and the SynergySeq Orthogonality Score. Application of iDOMO to triple-negative breast cancer (TNBC) identified drug pairs with potential synergistic effects, with the combination of trifluridine and monobenzone being the most synergistic. Our in vitro experiments confirmed that the top predicted drug combination exerted a significant synergistic effect in inhibiting TNBC cell growth. In summary, iDOMO is an effective method for the in silico screening of synergistic drug combinations and will be a valuable tool for the development of novel therapeutics for complex diseases.
CSGDN: contrastive signed graph diffusion network for predicting crop gene–phenotype associations
Authors: Pan Yiru , Ji Xingyu , You Jiaqi , Li Lu , Liu Zhenping , Zhang Xianlong , Zhang Zeyu , Wang Maojun 
Published: February 2025

Abstract
Positive and negative association prediction between gene and phenotype helps to illustrate the underlying mechanism of complex traits in organisms. The transcription and regulation activity of specific genes will be adjusted accordingly in different cell types, developmental timepoints, and physiological states. There are the following two problems in obtaining the positive/negative associations between gene and phenotype: (1) high-throughput DNA/RNA sequencing and phenotyping are expensive and time-consuming due to the need to process large sample sizes; (2) experiments introduce both random and systematic errors, and, meanwhile, calculations or predictions using software or models may produce noise. To address these two issues, we propose a Contrastive Signed Graph Diffusion Network, CSGDN, to learn robust node representations with fewer training samples to achieve higher link prediction accuracy. CSGDN uses a signed graph diffusion method to uncover the underlying regulatory associations between genes and phenotypes. Then, stochastic perturbation strategies are used to create two views for both original and diffusive graphs. Lastly, a multiview contrastive learning paradigm loss is designed to unify the node presentations learned from the two views to resist interference and reduce noise. We perform experiments to validate the performance of CSGDN in three crop datasets: Gossypium hirsutum, Brassica napus, and Triticum turgidum. The results show that the proposed model outperforms state-of-the-art methods by up to 9. 28% AUC for the prediction of link sign in the G. hirsutum dataset. The source code of our model is available at https://github.com/Erican-Ji/CSGDN.
Diagnostic accuracy of the faecal immunochemical test and volatile organic compound analysis in detecting colorectal polyps: meta-analysis
Authors: Afzal Asma , Aranan Yekaterina S , Roberts Tom , Covington James , Vidal Lorena , Ahmed Sonia , Gill Talvinder , Francis Nader 
Published: February 2025

Abstract

Background
For the early detection of colorectal cancer, it is important to identify the premalignant lesions to prevent cancer development. Non-invasive testing methods such as the faecal immunochemical test are well established for the screening and triage of patients with suspected colorectal cancer but are not routinely used for polyps. Additionally, the role of volatile organic compounds has been tested for cancer detection. The aim of this review was to determine the diagnostic accuracy of the faecal immunochemical test and volatile organic compounds in detecting colorectal polyps.

Methods
Original articles with diagnostic test accuracy measures for both the faecal immunochemical test and volatile organic compounds for advanced adenomas were included. Four databases including Medical Literature Analysis and Retrieval System Online (MEDLINE), Cumulative Index to Nursing and Allied Health Literature (CINAHL), Embase, and Web of Science were searched. The quality assessment tool for diagnostic accuracy study was used to assess the risk of bias and applicability. Meta-analysis was performed using RStudio® and the combined faecal immunochemical test-volatile organic compounds sensitivity and specificity were computed.

Results
Twenty-two faecal immunochemical tests and 12 volatile organic compound-related articles were included in the systematic review whilst 18 faecal immunochemical tests and eight volatile organic compound-related studies qualified for the meta-analysis. The estimated pooled sensitivity and specificity of the faecal immunochemical test to diagnose advanced adenoma(s) were 36% (95% c.i. 30 to 41) and 89% (95% c.i. 86 to 91) respectively, with an area under the curve of 0.65, whilst volatile organic compounds pooled sensitivity and specificity was 83% (95% c.i. 70 to 91) and 76% (95% c.i. 60 to 87) respectively, with an area under the curve of 0.84. The combined faecal immunochemical test-volatile organic compounds increased the sensitivity to 89% with a specificity of 67%.

Conclusion
Faecal immunochemical testing has a higher specificity but poor sensitivity for detecting advanced adenomas, while volatile organic compound analysis is more sensitive. The combination of both tests enhances the detection rate of advanced adenomas.
Understanding Immunological insights of Liver Transplantation: A practice for attaining Operational Tolerance
Authors: Dhayanithy Geethanjali , Radhakrishnan Subathra , Ann Martin Catherine , Caroline Martin Josette , Rahman Hakeem Abdul , Jothimani Dinesh , Narayana Kalkura Subbaraya , Rela Mohamed 
Published: February 2025

Abstract
Liver transplantation has been at the forefront of medical research, with efforts concentrated on understanding the intricate cellular and molecular dynamics involved this complex procedure. This body of work has chronicled critical clinical advancements, identified challenges, and highlighted progressive improvements in surgical practices. These concerted efforts have significantly contributed to the evolution and enhancement of liver transplantation, elevating it to its current level of sophistication. A successful liver transplant now demands an integrated, multidisciplinary approach that includes not only expanding the donor pool from deceased to living donors but also embracing advances in surgical methods, efficiently managing post-transplant complications, and, importantly, achieving operational tolerance. The latter, operational tolerance, is a state wherein the recipient’s immune system is coaxed into accepting the transplanted organ without the long-term use of immunosuppressive drugs, thereby minimizing potential side effects, and improving quality of life.
Understanding the critical immune mechanisms that aim to prevent graft rejection is essential from an immunological perspective. This review aims to highlight the crucial areas of host versus graft immune responses, making a clear distinction between organs received from living and deceased donors. It examines how these immune responses, both innate and adaptive, are initiated and proposes the exploration of molecular docking sites as a strategy to curb unwanted immune reactions. Additionally, this review explores the promising potential of biomarkers in predicting graft rejection, and emphasizes the importance of achieving tolerance and the continuous quest for innovative strategies to enhance the success and longevity of liver transplants.
Distinct insula subdivisions of resting-state functional connectivity in individuals with opioid and methamphetamine use disorders
Authors: Yang Wenhan , Wen Xinwen , Du Zhe , Yang Longtao , Chen Yanjing , Zhang Jun , Yuan Kai , Liu Jun 
Published: February 2025

Abstract

Different addictive drugs can impact the function and morphology of the brain in diverse ways. The insula cortex, an important brain node involved in craving and reward neural circuits in individuals with substance use disorders (including damage to the insula cortex), has been reported to reduce addictive behaviors. However, less is known about whether there is a functional difference between individuals with opioid and methamphetamine use disorders, especially regarding the function of the insula cortex. Fifty-eight individuals with opioid use disorder and sixty individuals with methamphetamine use disorder underwent resting-state and 3D-T1-weighted magnetic resonance imaging and completed craving questionnaires. Differences in insula subdivision resting-state functional connectivity between the groups were assessed, and their correlations with craving were analyzed. Compared with the methamphetamine group, the opioid group demonstrated increased connectivity of the right dorsal anterior insula but decreased connectivity of the right posterior insula and the left dorsal anterior insula/posterior insula/ventral anterior insula. Additionally, a negative correlation between functional connectivity and craving was observed in individuals with opioid and methamphetamine use disorders. This study provides insights into the various brain function connection patterns that are associated with different types of drug use with respect to opioid and methamphetamine use disorders.

Highlights
Impact of smoking habits on the postoperative outcome following lung surgery for cancer: results from the Epithor database
Authors: Leo Francesco , Migliaretti Giuseppe , Sobrero Simona , Angelescu Dan , Mc Bride Tarun , Dahan Marcel , Jougon Jacques ,   The Société Française De Chirurgie Thoracique Et Cardiovasculaire SFCTCV
Published: February 2025

Abstract

OBJECTIVES
Smoking is a modifiable risk factors for lung resections but to what extent preoperative smoking cessation reduces that risk remains unclear. The study hypothesis was that potential benefit of smoking cessation can be assessed measuring the risk difference between active and former smokers in a large cohort of patients.

METHODS
Data were extracted from the French Society of Thoracic and Cardiovascular Surgeons (SFCTCV) database. The study cohort was composed of patients who underwent lung resection for cancer from January 2002 to December 2020 and for which information on smoking status was available. The risk of overall and specific postoperative complications according to smoking status was defined by logistic regression models and results were presented in terms of OR and relative 95% confidence intervals adjusted for confounding factors.

RESULTS
Out of the 7204 analysed patients, at the time of surgery, 20.2% were active smokers, 60.7% ex-smokers and 19.1% never smokers. As compared to former smokers, active smokers experienced a higher rate of respiratory complications (OR 1.5, CI 1.2–1.7) and infections (OR 1.6, CI 1.3–1.9). Postoperative atelectasis was significantly reduced in former smoker (3%) as compared to active smokers (6.9%, p &lt; 0.01). In active smokers, the risk was related to the level of exposure, being higher for smokers of more than 40 P/Y.

CONCLUSIONS
After lung surgery, active smokers experience an higher risk of respiratory complications, infections and prolonged air leak as compared to former smokers. This risk seems to be related to the level of exposure.
Electrochemical performance improvement of coin cell lithium-ion lithium manganese dioxide battery
Authors: Shiue Angus , Chin Kai-Yen , Chen Po-Chou , Lin Jia-Xian , Lin Cheng-Liang , Chang Shu-Mei , Leggett Graham 
Published: February 2025

Abstract
Lithium-manganese oxide batteries are known for their long-term storage capabilities, characterized by low impedance and high discharge capacity. This study aims to enhance these properties by optimizing key battery components. XRD analysis of MnO2 (MD) powder, heat-treated at 400 °C for 5 hours, revealed improved discharge capacity. In addition, hot-pressed polypropylene nonwoven separators with electrolyte absorption exceeding 67 mg successfully reduced after-discharge impedance with minimal capacity loss (0.96%–1.26%). Last, the use of electrolyte additives led to a significant reduction in impedance for commercial electrolytes X and Y, contributing to overall battery performance improvement.
iHOT-12 item analysis: correlations between individual items and overall score within and across time points
Authors: Yuro Matthew , Martin Robroy , Wolff Andrew B , Nho Shane , Wuerz Thomas , Thiel Geoff Van , Christoforetti John , Salvo John P , Matsuda Dean , Carreira Dominic S 
Published: February 2025

Abstract
The main aim of this study was to analyze correlations between individual international hip outcome tool 12 (iHOT-12) items and overall iHOT-12 score within and across timepoints. A retrospective multicenter hip arthroscopy registry was queried for patients from January 2014 to October 2023 with completed iHOT-12 reports. Pearson coefficient analysis was used to identify correlations between individual iHOT-12 items and overall iHOT-12 score at each timepoint and between preoperative individual iHOT-12 items and postoperative overall iHOT-12 scores. Validity, reliability, and responsiveness of the iHOT-12 were analyzed at each timepoint. Within timepoints, correlations ranged in strength from fair (preoperative maintain fitness level, r = 0.52, P &lt; .00001) to excellent (5-year hip pain after activity, r = 0.93, P &lt; .00001). Correlations increased in strength over time. Across timepoints, correlations ranged in strength from no correlation (2-year maintain fitness level, r = −0.001, P = 0.94) to poor (6-month pushing or lifting heavy objects, r = 0.31, P &lt; .00001). Correlations decreased in strength over time. No ceiling or floor effects were exhibited. The Cronbach alpha for the baseline, 6-month, 1-year, 2-year, and 5-year timepoints were 0.87, 0.96, 0.95, 0.96, and 0.97, respectively. Cohen’s d values at 6 months, 1 year, 2 years, and 5 years were 1.19, 1.43, 1.71, and 1.58, respectively. Within timepoints, hip pain after activity had the strongest correlations to overall iHOT-12 score. Across timepoints, correlations between preoperative individual iHOT-12 items and postoperative overall iHOT-12 score were poor and weakened over time, suggesting similar long-term postoperative iHOT-12 scores among both high- and low-scoring preoperative patients. The iHOT-12 demonstrated good validity, reliability, and responsiveness at all timepoints.
Beats, Tactility, and the Politics of Deaf Representation in EDM
Authors: Holmes Jessica 
Published: February 2025

Abstract
This chapter challenges the symbolic prestige of “deafness” in electronic dance music (EDM) culture as it reflects on monolithic constructions of loudness, vibration, and tactility therein. It reveals that the music video for electronic musician Jamie xx’s 2014 track “Sleep Sound” champions a one-to-one overcoming logic that supplants hearing with tactility to the exclusion of vision, residual hearing, and technology in deaf experiences of EDM; the video appropriates deafness to affirm its white hearing bias while obscuring the sensory multiplicity of deaf subjecthood. The chapter’s discussion of DJ Troi Lee, founder of the Deaf-led musical collective Deaf Rave, rather sheds light on the material contingencies of vibration and tactility, and the reliability of vision and visuality as perceptual and expressive devices by contrast. It is argued that EDM is not automatically inclusive of deafness by virtue of any tactile substrata; rather, the synergy between EDM and deafness is cultivated and maintained through deaf perceptual agency.
Transmissions
Authors: Dilday Jess 
Published: February 2025

Abstract
Trans and non-binary underground electronic music producers and DJs have always been at the forefront of club trends, from the sound to the fashion. However, we are often not supported by the music industries that borrow so readily from our aesthetics, so we create our own communities, our own families, and our own industries. While in-person connections are always ideal, trans and non-binary DJs and producers prominently use social media such as Twitter and music streaming sites such as SoundCloud and Bandcamp to network with each other and to build each other up through online promotion and citation practices.