bluuebunny/crossref_metadata_2025_split huggingface dataset:
Can visual language convey tactile experience? A study of the tactile compensation effect of visual language for online products
Authors: Leng Xionghui , Zhou Xiaoyu , Wang Shuting , Xiang Yibin 
Published: December 2022

IntroductionThere is a common phenomenon of tactile missing in online retail. How to realize consumer tactile compensation is a consensus problem in the field of e-commerce. More and more marketeers and scholars convey their ideas via visual display, but few researches have focused on the tactile compensatory effect of visual language.MethodsStudy 1 collected data from nearly 13,000 online purchases to analyze the impact of haptic cues on sales in real online shopping platforms; Study 2 used a experimental research method to design three experimental groups: hand haptic cue group vs. Object haptic cue group vs. control group (N = 165) to investigate whether the main effect of haptic cues and the dual mediating effect of mental simulation held. Study 3 also adopted a simulated experimental research approach to design a two-factor group: 2 (haptic cue: hand vs. object) × 2 (product type: tactile functional product vs. tactile experiential product) (N = 198). To further explore whether the moderating effect of product type holds based on Study 2.ResultsTherefore, based on the visualization theory and mental simulation theory, and through a second-hand data experiment and two simulated experiments, this study confirmed that visual language did have a compensation effect on tactile missing specifically. Haptic cues in metaphorical visual language can actively compensate for consumers’ tactile loss, thus affecting the purchase intention. Mental simulation plays a mediating role in the tactile compensation effect. Product type has a moderating effect, and the use of hand (object) haptic cues in metaphorical visual language in tactile functional products (tactile experiential products) can lead to a more active purchase intention.DiscussionThis study not only enriches the theoretical research on the tactile compensation effect of visual language, but also provides valuable management enlightenment for e-commerce enterprises to improve the effectiveness of online product display and online sensory marketing strategies.
The effect of mobile phone addiction on perceived stress and mediating role of ruminations: Evidence from Chinese and Czech university students
Authors: Liu Hongyang , Novotný Jan Sebastian , Váchová Lucie 
Published: December 2022

IntroductionThe rise in the capabilities of mobile devices and the associated increase in the proportion of time we spend on them has not only positive benefits but also several risks, including mobile phone addiction and its consequences. The complex mechanisms of the impact of this addiction on mental health, especially in a cross-cultural context, however, remain relatively unknown. The aim of this cross-cultural study was to investigate the mediating role of rumination on the association between mobile phone addiction and perceived stress.MethodsA population of 358 Chinese and 282 Czech university students was tested using a battery of validated psychological tests that included a short version of the Smartphone Addiction Scale, the Ruminative Response Scale, and the Perceived Stress Scale.ResultsThe results showed significant cross-cultural differences with Czech students manifesting greater rumination (d = 0.79) and perceived stress (d = 0.42) and Chinese students showing greater mobile phone addiction (d = 1.01). Mediation analyses showed that the effect of mobile phone addiction on stress levels was mediated through the rumination in both populations (45.6% and 80.9% of the explained variance for Chinese and Czech students, respectively) and did not differ between the two countries (estimate of difference [95%CI] = −0.052[−0.166, 0.037], p = 0.27). In contrast, the significant direct effect of mobile phone addiction on perceived stress was only present in Chinese students, where it was marginally larger than the indirect effect. In Czech students, the direct effect was not manifested and the difference between countries was significant (estimate of difference [95%CI] = 0.242 [0.035, 0.413], p &lt; 0.001). In all of the cases, the association between the variables was positive, i.e., as one grew, so did the other. Finally, a moderated-mediation analysis confirmed that country of origin significantly moderated only the direct relationship between mobile phone dependence and perceived stress (p = 0.002).DiscussionThese results suggest that the mechanism of interaction between excessive mobile phone use and perceived stress is culturally conditioned, which may limit the transferability of research findings in a global context and requires further cross-cultural studies.
Maladaptive coping among military-connected adolescents: Examining combined risk using QCA
Authors: Gilreath Tamika D. , Montiel Ishino Francisco A. , Sullivan Kathrine S. , Okoror Titilayo A. 
Published: December 2022

IntroductionMilitary-connected students in public schools face a unique set of stressors that may impact their wellbeing and academic functioning.MethodsTwenty-four youth in the 7th to 12th grades who had an active-duty parent (mother or father) serving in the U.S. Armed Forces were interviewed. Participants completed a qualitative interview while actively completing a Life History Calendar (LHC) to mark deployment and family military service milestones and discuss how they impacted the youth respondent. This study used Qualitative Comparative Analysis (QCA) to explore the interplay and combination of specific stressors related to relocation and deployment experiences among adolescents, and to determine key factors associated with maladaptive outcomes.ResultsThe results of the QCA analysis identified bullying experiences and negative experiences with other military-connected youth as conditions that are associated with maladaptive coping.DiscussionChronic and acute stressors in adolescence are established risk factors for mental, emotional, and behavioral problems in the short and long-term including suicidality, substance use and abuse, and substance use disorders. Through qualitative inquiry we were able to identify specific contextual details related to maladaptive coping that can be used to further refine areas of focus for research, prevention, and interventions for military-connected adolescents.
The association between lower socioeconomic position and functional limitations is partially mediated by obesity in older adults with symptomatic knee osteoarthritis: Findings from the English Longitudinal Study of Ageing
Authors: Witkam Rozemarijn , Verstappen Suzanne M. M. , Gwinnutt James M. , Cook Michael J. , O'Neill Terence W. , Cooper Rachel , Humphreys Jennifer 
Published: December 2022

ObjectiveTo assess the longitudinal associations of socioeconomic position (SEP) with functional limitations and knee joint replacement surgery (JRS) in people with symptomatic knee osteoarthritis (OA), and whether body mass index (BMI) mediated these relationships.MethodsData came from the English Longitudinal Study of Ageing, a national longitudinal panel study of adults aged ≥50 years. A total of 1,499 participants (62.3% female; mean age 66.5 (standard deviation (SD) 9.4) years; 47.4% obese) self-reporting an OA diagnosis and knee pain, with at least one BMI measurement were included. Mixed effect models estimated longitudinal associations of each SEP variable (education, occupation, income, wealth and deprivation index) and obesity (BMI ≥30.0 kg/m2) with repeated measures of functional limitations. Cox regression analyses estimated associations between SEP indicators and obesity at baseline and risk of knee JRS at follow-up. Structural equation modeling estimated any mediating effects of BMI on these relationships.ResultsLower SEP and obesity at baseline were associated with increased odds of functional limitations in people with knee OA [e.g., difficulty walking 100 yards: no qualification vs. degree adjOR 4.33 (95% CI 2.20, 8.55) and obesity vs. no obesity adjOR 3.06 (95% CI 2.14, 4.37); similar associations were found for the other SEP indicators]. A small proportion of the association between lower SEP and functional limitations could be explained by BMI (6.2–12.5%). Those with lower income, lower wealth and higher deprivation were less likely to have knee JRS [e.g., adjHR most vs. least deprived 0.37 (95% CI 0.19, 0.73)]; however, no clear association was found for education and occupation. Obesity was associated with increased hazards of having knee JRS [adjHR 1.87 (95% CI 1.32, 2.66)]. As the direction of the associations for SEP and obesity with knee JRS were in opposite directions, no mediation analyses were performed.ConclusionsLower SEP was associated with increased odds of functional limitations but lower hazards of knee JRS among people with knee OA, potentially indicating underutilization of JRS in those with lower SEP. Obesity partially mediated the relationship between lower SEP and increased odds of functional limitations, suggesting adiposity as a potential interventional target.
The dose-response relationship between BMI and hypertension based on restricted cubic spline functions in children and adolescents: A cross-sectional study
Authors: Wang Yani , Min Congcong , Song Xiaoyan , Zhang Heyue , Yuan Chen , Chen Lizhen , Zhang Haiying 
Published: December 2022

BackgroundA high body mass index (BMI) is a major risk factor for hypertension. The purpose of this study was to investigate the association between the BMI and hypertension in children and adolescents.MethodsWe analyzed physical examination data from 29,810 students aged 6–14 years old. A restricted cubic spline (RCS) function was used to investigate the dose-response relationship between the BMI and hypertension.ResultsThe prevalence of hypertension was 9.91%, followed by 11.71% in males and 7.9% in females, respectively. Compared to the normal weight group, the odds risk (OR) for hypertension in the overweight group was 1.729, and the OR for hypertension in the obesity group was 3.089. After adjusting for potential confounders, the adjusted ORs were 1.620 [95% confidence interval (CI): 1.457–1.800] in the overweight group and 3.092 (95% CI: 2.824–3.385) in the obesity group. According to the multivariate RCS regression analysis, there was a significant non-linear dose-response association between the BMI and the risk of hypertension (all P-values for non-linear &lt; 0.001).ConclusionThe dose-response relationship analysis showed that the association strength of hypertension increased non-linearly along with the continuous change of BMI in children and adolescents.
Renal Function, Adherence and Quality of Life Improvement After Conversion From Immediate to Prolonged-Release Tacrolimus in Liver Transplantation: Prospective Ten-Year Follow-Up Study
Authors: Toti Luca , Manzia Tommaso Maria , Blasi Francesca , Lenci Ilaria , Baiocchi Leonardo , Toschi Nicola , Tisone Giuseppe 
Published: December 2022

Immunosuppression non-adherence is a major cause of graft failure after liver transplantation. The aim of this study was to evaluate practice surrounding conversion from immediate-release to prolonged-release Tacrolimus formulation and to assess patient adherence and quality of life (QoL). One hundred and seven adult liver transplant recipients, receiving immediate-release Tacrolimus for a minimum of 6 months, were converted to prolonged-release formulation, based on a dose ratio of one (1:1). The median follow-up was 120 [IQR, 120–123] months. Tacrolimus dosage and blood level, liver and renal function, lipid and glucose profiles were recorded. In addition, questionnaires were submitted to evaluate adherence and QoL following conversion. No rejection was recorded. The median serum Tacrolimus blood level decreased over 1 month (5.80, [IQR, 2.0–10.8] vs. 3.8 [IQR, 1.4–8.7]; p &lt; 0.0005). Significant improvement in renal function was noted (median GFR was 81.7 [IQR, 43.4–128.6] vs. 73.9 [IQR, 27.1–130.2]; p = 0.0002). At the end of the follow-up, conversion resulted in an overall decrease in non-adherence of 53.3% (p = 0.0001) and an improvement in QoL was reported by 76.2% of patients. Thus, 1:1 conversion from immediate to prolonged-release Tacrolimus is safe, feasible and efficient, avoiding under-therapeutic and toxic peak concentrations, improving renal function, adherence to immunosuppression and overall patient QoL.
Evaluation of Undergrowth under the Canopy of Deciduous Forests on Very Fertile Soils in the Lithuanian Hemiboreal Forest
Authors: Šilingas Marius , Suchockas Vytautas , Varnagirytė-Kabašinskienė Iveta 
Published: December 2022

In the hemiboreal forest zone, the first-generation natural forests of Betula spp., Populus tremula L., and Alnus incana (L.) Moench, which develop after clearcutting on very fertile forest sites, change to deciduous hardwood forests (Quercus robur L., and Fraxinus excelsior L.) due to successive processes. These processes also cause a specific response to the development of undergrowth species, which can have a decisive influence on forest regeneration. The undergrowth species in the mature Betula spp. (Betula pendula Roth. And Betula pubescens Ehrh.), Populus tremula, and Alnus incana forest stands were evaluated to provide knowledge on undergrowth species composition and development under different soil conditions, and to identify the forest stand age’s impact on undergrowth species. The evaluation was based on the standwise forest inventory data and limited to the analysis of pioneer tree species forests usually developed as first-generation natural forests after clearcutting. The study results showed that deciduous forests have rich undergrowth species diversity with a dominance of the Corylus avellana L., Padus avium L., Frangula alnus Mill., Sorbus aucuparia L., and Salix spp., which are typical undergrowth species in the hemiboreal forest zone. The dense and medium density undergrowth with the predominant Corylus avellana was rather common in the Betula spp. and Populus tremula stands; and Padus avium was more abundant in the Alnus incana stands on very fertile sites. Larger areas with dense undergrowth were obtained in the low mixed and mixed Alnus incana stands than in the pure stands, while no clear relationship between the stand mixture and undergrowth density was obtained in the Betula spp. and Populus tremula stands. The area of Corylus avellana significantly increased, while the area of Padus avium decreased in all studied forests with increasing stand age. Other dominant undergrowth species–Sorbus aucuparia, Frangula alnus, and Salix spp.–decreased with increasing age of the Betula spp. and Populus tremula stands. In the context of biodiversity, a higher number of undergrowth species was obtained in the mixed Betula spp. stands than in the pure and low mixed stands. New insights about the undergrowth species and their development patterns under the canopy of pioneer deciduous forests on very fertile soils were provided. However, these findings do not strongly suggest that an unmanaged forest regime wins over conventional forest management in mature and older deciduous forests on fertile soils as regards the biodiversity and other ecological services provided by the undergrow species.
LC-MS/MS-Based Metabolomic Profiling of Constituents from Glochidion velutinum and Its Activity against Cancer Cell Lines
Authors: Shah Syed Luqman , Bashir Kashif , Rasheed Hafiz Majid , Rahman Jamil Ur , Ikram Muhammad , Shah Abdul Jabbar , Majrashi Kamlah Ali , Alnasser Sulaiman Mohammed , Menaa Farid , Khan Taous 
Published: December 2022

This study aimed to establish the phytochemical profile of Glochidion velutinum and its cytotoxic activity against prostate cancer (PC-3) and breast cancer (MCF-7) cell lines. The phytochemical composition of G. velutinum leaf extract and its fractions was established with the help of total phenolic and flavonoid contents and LC-MS/MS-based metabolomics analysis. The crude methanolic extract and its fractions were studied for pharmacological activity against PC-3 and MCF-7 cell lines using the MTT assay. The total phenolic content of the crude extract and its fractions ranged from 44 to 859 µg GAE/mg of sample whereas total flavonoid contents ranged from 20 to 315 µg QE/mg of sample. A total of forty-eight compounds were tentatively dereplicated in the extract and its fractions. These phytochemicals included benzoic acid derivatives, flavans, flavones, O-methylated flavonoids, flavonoid O- and C-glycosides, pyranocoumarins, hydrolysable tannins, carbohydrate conjugates, fatty acids, coumarin glycosides, monoterpenoids, diterpenoids, and terpene glycosides. The crude extract (IC50 = 89 µg/mL), the chloroform fraction (IC50 = 27 µg/mL), and the water fraction (IC50 = 36 µg/mL) were found to be active against the PC-3 cell line. However, the crude extract (IC50 = 431 µg/mL), the chloroform fraction (IC50 = 222 µg/mL), and the ethyl acetate fraction (IC50 = 226 µg/mL) have shown prominent activity against breast cancer cells. Moreover, G. velutinum extract and its fractions presented negligible toxicity to normal macrophages at the maximum tested dose (600 µg/mL). Among the compounds identified through LC-MS/MS-based metabolomics analysis, epigallocatechin gallate, ellagic acid, isovitexin, and rutin were reported to have anticancer activity against both prostate and breast cancer cell lines and might be responsible for the cytotoxic activities of G. velutinum extract and its bioactive fractions.
In Vitro and In Vivo Antihypertensive Effect of Milk Fermented with Different Strains of Common Starter Lactic Acid Bacteria
Authors: Glazunova Olga A. , Moiseenko Konstantin V. , Savinova Olga S. , Fedorova Tatyana V. 
Published: December 2022

Currently, functional dairy products pave a promising way for the prophylaxis of essential hypertension, and the search for new strains capable of producing such products is a constant challenge for scientists around the world. In this study, the antihypertensive properties of milk fermented with several strains of traditional yogurt starters (Lactobacillus delbrueckii strains Lb100 and Lb200; Lactococcus lactis strains dlA, AM1 and MA1; Streptococcus thermophilus strains 159 and 16t) and one strain of non-conventional probiotic starter (Lacticaseibacillus paracasei ABK) were assessed. The in vitro assessment using angiotensin-converting enzyme inhibition assay was performed for all fermentation products, and the best performed products were tested in vivo using Spontaneously Hypertensive Rat (SHR) animal model. In addition, for the best performed products the fatty acid (FA) composition and FA-related nutritional indices were determined. As a result, the milk fermented with two strains (Lb. delbrueckii LB100 and Lc. lactis AM1) demonstrated significant antihypertensive effect during both in vitro and in vivo experiments. Moreover, the milk fermented with Lb. delbrueckii Lb100 demonstrated significantly better FA-related nutritional indexes and lowered total cholesterol in SHRs upon regular consumption. The obtained results can be used in the future to develop new starter cultures producing effective functional antihypertensive dairy products.
An Improved Exponential Model Considering a Spectrally Effective Moisture Threshold for Proximal Hyperspectral Reflectance Simulation and Soil Salinity Estimation
Authors: Huang Xi , Bai Tiecheng , Guan Huade , Wei Xiayong , Wang Yali , Mao Xiaomin 
Published: December 2022

Soil salinization has become one of the main factors restricting sustainable development of agriculture. Field spectrometry provides a quick way to predict the soil salinization. However, soil moisture content (SMC) seriously interferes with the spectral information of saline soil in arid areas. It is vital to establish a model that is insensitive to SMC for potential in situ field applications. The soil spectral reflectance exponential model (SSREM) has been widely employed for reflectance simulation and SSC inversion. However, its reliability for saline soils with high SMC has not been verified yet. Based on hyperspectral remote sensing data (400~1000 nm) on 459 saline soil samples in Shiyang River Basin of Northwest China, we investigated the role of SMC and SSC in soil spectral reflectance from 29 October 2020 to 22 January 2021. Targeted at saline soils, soil spectral moisture threshold (MT) was introduced to improve the SSREM toward a modified spectral reflectance exponential model (MT-SSREM). The bands that are sensitive to SSC but not sensitive to SMC were obtained based on a method of correlation analysis between original spectra, four kinds of spectral data, and SSC. SSREM and MT-SSREM were finally applied to inversely estimate SSC. Results show that wavelengths at 658~660, 671~685, 938 nm were suitable for SSC estimation. Furthermore, although SSREM was able to simulate the spectral reflectance of most saline soils, its simulation accuracy was low for saline soil samples with high SMC (SMC > MT(i), 400 nm≤i≤1000 nm), while MT-SSREM performed well over the whole range of SMC. The simulated spectral reflectance from MT-SSREM agreed well with the measured reflectance, with the R2 being generally larger than 0.9 and RMSE being less than 0.1. More importantly, MT-SSREM performed substantially better than SSREM for SSC estimation; in the statistical performance of the former case, R2 was in range of 0.60~0.66, RMSE was in range of 0.29~0.33 dS m−1; in the latter case, R2 was in range of 0.10~0.16, RMSE was in the range of 0.26~0.29 dS m−1. MT-SSREM proposed in this study thus provides a new direction for estimating hyperspectral reflectance and SSC under various soil moisture conditions at wavelengths from 400 to 1000 nm. It also provides an approach for SSC and SMC mapping in salinization regions by incorporating remote sensing data, such as GF-5.
Incremental Peritoneal Dialysis—Definition, Prescription, and Clinical Outcomes
Authors: Fernandes Adriana , Matias Patrícia , Branco Patrícia 
Published: December 2022

ABSTRACT
Incremental peritoneal dialysis (IPD) is a strategy of RRT that is based on the prescription of a lower dose rather than the standard full dose of peritoneal dialysis (PD). The clearance goals are achieved through the combination of residual kidney function (RKF) and peritoneal clearance. The dialysis prescription should be increased as the RKF declines. IPD has been associated with clinical, economic, and environmental advantages. We emphasize possible better quality of life, fewer mechanical symptoms, lower costs, slight adverse metabolic effects, and less plastic waste and water consumption. The potential benefits for RKF preservation and the lower risk of peritonitis have also been discussed. There are some concerns regarding this strategy, such as inadequate clearance of uremic toxins and/or severe electrolyte disturbances due to undetected loss of RKF, lower clearance of medium-sized molecules (such as β-2-microglobulin) which mostly depends on the total PD dwell time, and patients' reluctance to dose adjustments. Current clinical evidence is based on moderate-quality to low-quality studies and suggests that the outcomes of IPD will be at least identical to those of full dose. This review aims to define IDP, discuss strategies for prescription, and review its advantages and disadvantages according to the current evidence.