bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH MOBILISASI DINI TERHADAP PROSES INVOLUSI UTERI
Authors: Hikhmat Rokhmatul , Lestari Sri , Dewi Ning Puspita 
Published: March 2022

Pelaksanaan tindakan mobilisasi dini pada pasien post sectio caesaria rata-rata baru mencapai 23,3% dari seluruh persalinan di rumah sakit Karya Husada, padahal mobilisasi dini merupakan tindakan yang sangat efektif guna mencegah komplikasi pada pasien post sectio caesaria. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian mobilisasi dini terhadap proses involusi uteri pada pasien post sectio saesaria. Jenis penelitian ini adalah Quasi Eksperimen atau eksperimen semu. instrumen yang digunakan adalah kuesioner dengan pertanyaan tertutup. Jumlah responden 30 responden dalam kelompok kontrol 15 responden dan kelompok intervensi 15 responden. Hasil penelitian bahwa nilai rata-rata penurunan TFU pada kelompok kontrol adalah paling banyak pada skala 0,5 cm yaitu sebanyak 5 orang (33,3%). pada responden kelompok intervensi paling banyak pada nilai 2,5 – 3 cm yaitu sebanyak 8 orang (73,3%). Uji statistik menggunakan uji T-Test diketahui bahwa terdapat perbedaan yang bermakna antara rata - rata penurunan TFU kelompok intervensi dengan kelompok kontrol pada pasien post sectio caesaria, dimana nilai signifikansi 0,023 < α 0,05. Saran dari penelitian ini bagi rumah sakit agar pelaksanaan tindakan pemberian mobilisasi dini pada pasien post sectio caesaria lebih ditingkatkan guna menjamin kualitas asuhan keperawatanKata Kunci: Mobilisasi Dini, Involusi Uteri, Post Sectio Caesaria ABSTRACTThe implementation of early mobilization in post sectio caesaria patients only reached 23.3% of all deliveries at the Karya Husada hospital, even though early mobilization is a very effective measure to prevent complications in post sectio caesaria patients. This study aims to determine the effect of early mobilization on the process of uterine involution in post sectio saesaria patients. The type of research is Quasy Experiment or quasi-experiment. The instrument used was a questionnaire with closed questions. The number of respondents was 30 respondents in the control group 15 respondents and the intervention group 15 respondents. The results showed that the average TFU reduction in the control group was the most on a scale of 0.5 cm, namely 5 people (33.3%). The most respondents in the intervention group were at a value of 2.5 - 3 cm, namely as many as 8 people (73.3%). Statistical test using the T-Test shows that there is a significant difference between the average reduction in TFU of the intervention group and the control group in post sectio caesaria patients, where the significance value is 0.023 <α 0.05.Suggestions from this study for hospitals so that the implementation of early mobilization in post sectio caesaria patients is further improved in order to ensure the quality of nursing careKeywords: Early Mobilization, Uterine Involution, Post Sectio Caesaria
The Second Catalog of Interplanetary Network Localizations of Konus Short-duration Gamma-Ray Bursts
Authors: Svinkin D. S. , Hurley K. , Ridnaia A. V. , Lysenko A. L. , Frederiks D. D. , Golenetskii S. V. , Tsvetkova A. E. , Ulanov M. V. , Kokomov A. , Cline T. L. , Mitrofanov I. , Golovin D. , Kozyrev A. , Litvak M. , Sanin A. , Goldstein A. , Briggs M. S. , Wilson-Hodge C. , Burns E. , von Kienlin A. , Zhang X.-L. , Rau A. , Savchenko V. , Bozzo E. , Ferrigno C. , Barthelmy S. , Cummings J. , Krimm H. , Palmer D. M. , Tohuvavohu A. , Yamaoka K. , Ohno M. , Fukazawa Y. , Hanabata Y. , Takahashi T. , Tashiro M. , Terada Y. , Murakami T. , Makishima K. , Boynton W. , Fellows C. W. , Harshman K. P. , Enos H. , Starr R. , Goldsten J. , Gold R. , Ursi A. , Tavani M. , Bulgarelli A. , Casentini C. , Del Monte E. , Evangelista Y. , Galli M. , Longo F. , Marisaldi M. , Parmiggiani N. , Pittori C. , Romani M. , Verrecchia F. , Smith D. M. , Hajdas W. , Xiao S. , Cai C. , Yi Q. B. , Zhang Y. Q. , Xiong S. L. , Li X. B. , Huang Y. , Li C. K. , Zhang S. N. , Song L. M. , Liu C. Z. , Li X. Q. , Peng W. X. , Martinez-Castellanos I. 
Published: March 2022

Abstract
We present the catalog of InterPlanetary Network (IPN) localizations for 199 short-duration gamma-ray bursts (sGRBs) detected by the Konus-Wind (KW) experiment between 2011 January 1 and 2021 August 31, which extends the initial sample of IPN-localized KW sGRBs to 495 events. We present the most comprehensive IPN localization data on these events, including probability sky maps in Hierarchical Equal Area isoLatitude Pixelization format.
Cytotoxic activities of ethanolic crude extracts from fruiting bodies of bamboo mushrooms (Dictyophora spp.) against cholangiocarcinoma cells
Authors: Chantree Pathanin , Chumkiew Sirilak , Jamklang Mantana , Martviset Pongsakorn 
Published: March 2022

Introduction: Cholangiocarcinoma (CCA) is a highly progressive tumor. The standard chemotherapy varies in its effectiveness, with generally low efficacy. So, the discovery of novel chemotherapy is still required. The objective of this preliminary study was to determine the cytotoxic effects induced by three kinds of bamboo mushrooms (Dictyophora indusiata or Chinese bamboo mushroom; Ch-DTP, Short skirt bamboo mushroom (Thai isolate); Th-DTP, and orange skirt bamboo mushroom; Or-DTP) on CCA cells.
Materials and methods: CCA cell lines, including CL-6, HuCCT1, HuH28, and OUMS normal fibroblast cells, were treated with various concentrations of DTP extracts. The MTT assay was used to determine cytotoxicity, and cell morphology was observed by using phase-contrast microscopy.
Results and discussion: The results suggested that Ch-DTP effectively killed all three CCA cell lines in both low (0.3 mg/mL) and high (0.6 mg/mL) doses, but Th-DTP and Or-DTP had significantly reduced cell viability only at high doses (p<0.001). Ch-DTP had the best effect by showing a response of more than 50% at a concentration of 0.3 mg/mL. Th-DTP had moderate effects at a concentration of lower than 0.6 mg/mL but worthwhile at higher concentrations, whereas Or-DTP had limited effects at concentrations of 0.4 mg/mL and downward, although the effects were significantly increased in the higher concentration range. Morphology of the Ch-DTP treated cells was greatly transformed both at low and high doses, but Th-DTP and Or-DTP showed definite alteration only at high doses. The morphological changes revealed apoptotic induction. In OUMS cells, no effects were recognized with any of the three DTPs.
Conclusion: This study indicated that DTP extracts could induce cytotoxicity in cholangiocarcinoma, with a high potential of being an effective therapeutic agent.
Obstétrique, (non)violence et féminisme
Authors: Topçu Sezin 
Published: March 2022

De nombreux problèmes au cœur de l’actuelle controverse sur les violences obstétricales ont déjà été mis sur la table dans la France des années 1970. Cet article met le projecteur sur les critiques forgées et les expériences alternatives lancées durant cette période pour faire face à l’expansion des doctrines, normes et pratiques médicales jugées mal-traitantes. Notre objectif est de décrypter en particulier la manière dont le concept de non-violence est alors pensé, théorisé et mis en pratique, les dynamiques qu’il a fait émerger, et les tensions multiples et variées qu’il a engendrées, au sein notamment du mouvement féministe.
Un método para establecer la viabilidad de las poblaciones de la araña trampera Amblyocarenum en áreas urbanas: un estudio piloto
Authors: Calatayud-Mascarell Arnau , Migueles-Miralles Luna 
Published: March 2022

Amblyocarenum walckenaeri (Lucas, 1846) (Araneae: Mygalomorphae: Nemesiidae) se encuentra en varias zonas urbanas de La Safor (Valencia, España). Aquí, presentamos un método que podría exponer el efecto perturbador de la rápida expansión urbana en poblaciones de arañas tramperas: contando las clases de edades de una población como indicador de su viabilidad. Nuestros resultados muestran que la mayoría de las poblaciones urbanas muestreadas no presenta crías. Esto sugiere que Amblyocarenum existe en dichas zonas urbanas como remanentes; poblaciones envejecidas que presentan dificultad a la hora de reclutar nuevas generaciones de ejemplares, tornándose inviables.
Localización y confirmación de la existencia del holotipo de Plagionotus andreui Fuente, 1908 (Coleoptera: Cerambycidae)
Authors: Fernández-Carrillo‍ Enrique , Fernández-Carrillo‍ José Luis 
Published: March 2022

Se localiza y se confirma la existencia del holotipo de Plagionotus andreui Fuente 1908, en la colección Fuente. Se realiza un resumen de la historia nomenclatural y taxonómica de la especie hasta el presente.
Chapitre 3. Il contesto geologico e l’evoluzione quaternaria della valle del fiume Tavo e del torrente Gallero
Authors: Agostini Silvano 
Published: March 2022

Il bacino idrografico del fiume Tavo e del suo affluente Gallero si estende dal versante orientale del Gran Sasso, dove scolpisce le formazioni pertinenti alla successione carbonatica ceno-mesozoica in facies di scarpata – bacino, per ampliarsi verso est nella zona collinare fino al mare Adriatico, dove il substrato è invece costituito da successioni silico clastiche (arenarie, peliti, marne, argille) a cui si intercalano – come a Montebello di Bertona – banchi di conglomerati con clasti prevalentemente calcarei. Il Quaternario è rappresentato da forme relitte, quali superfici di paleopaesaggio, depositi di versante (brecce e coltri detritiche), corpi di frana, coltri colluviali ed unità alluvionali terrazzate e sospese a quote diverse. Gli alvei attuali sono profondamente incassati all’interno dell’unità alluvionale riferita all’ultimo tardiglaciale. Sulle sommità e all’interno delle unità alluvionali terrazzate sono conservati lembi di paleosuoli. L’elevata energia di rilievo, che evidenzia un continuo e discreto tasso di sollevamento areale per tutto il Pleistocene medio e superiore, si esprime con processi di ringiovanimento e di modellamento che hanno lasciato sospesi forme e depositi depostisi in contesti morfoclimatici differenti. In particolare le associazioni di facies dei depositi clastici a margine del rilievo montano e delle unità alluvionali del Tavo e del Gallero permettono di ricostruire l’evoluzione paleogeografica, i paesaggi e gli ambienti del Pleistocene superiore.Particolare attenzione è stata posta all’analisi della selce presente nelle formazioni della successione carbonatica affioranti, nel bacino idrografico e oltre i suoi margini, sia in forma di arnioni, che di letti discontinui o in strati sottili. Grana e colori della selce, consistenza e spessore del cortice, omogeneità e qualità, assenza, presenza e spaziatura di microfratture formazioni risultano tipici della selce presente in ciascuna delle carbonatiche. Nelle unità alluvionali pleistoceniche, la selce si rinviene negli orizzonti grossolani costituiti da ghiaie, come ciottoli sia integri che spezzati, e più diffusamente in schegge minute non utilizzabili.
Chapitre 5. La vallée du Gallero au tardiglaciaire
Authors: Le Jeune Yann 
Published: March 2022

Les recherches menées à Campo delle Piane ont accordé une large place à l’étude paléoenvironnementale. Les observations stratigraphiques effectuées dans la vallée du Gallero et la cartographie des dépôts sédimentaires font apparaître la présence d’un ancien cône de déjection en contexte de piémont qui s’est formé sous un régime nival. L’incision importante du Gallero (une vingtaine de mètres) est rapportée au début de l’Holocène en relation avec le changement climatique (passage d’un régime nival à pluvio-nival) conjuguée avec une forte activité tectonique classique dans la région. Les dépôts tardiglaciaires prennent donc localement la forme d’une terrasse. Leur conservation et celle des vestiges épigravettiens résultent principalement de cette incision holocène des cours d’eau et de l’érosion provoquée par l’agriculture.La séquence sédimentaire surmontant le niveau épigravettien trouvé dans le locus n° 7 (CDP 7) constitue une coupe de référence. Ce niveau se situe sur la pente d’un ancien dôme de graviers et à proximité d’un chenal qui sont des formes héritées de la morphogenèse weichselienne. Il est associé à un paléosol brun-rouge dont la conservation est liée au comblement de ce chenal.L’étude fine de cette séquence permet de reconstituer des éléments du paléoenvironnement et de la paléoclimatologie du Tardiglaciaire dans la vallée du Gallero. L’observation macroscopique et les analyses physico-chimiques des sédiments montrent l’existence de deux paléosols distincts associés à des traces d’incendies. Le paléosol supérieur, daté par le carbone 14, est attribué à l’interstade Bølling-Allerød. La corrélation du paléosol inférieur contenant les vestiges archéologiques avec un interstade précis repose sur plusieurs datations (carbone 14 et OSL) qui le placent entre 17 ka et 21.1 ka cal. BP et sur la confrontation avec des références lointaines, de portée générale (carottes de glaces polaires et marines), et des travaux plus rapprochés réalisés en Italie (Lago di Monticchio, bassin du Fucino et Apennins). Ce paléosol semble correspondre à une période d’amélioration climatique du G2sb (Greenland Interstadial 2b), antérieure au Dryas I et postérieure au Dernier Maximum Glaciaire. C’est durant cet épisode de réchauffement et dans un environnement de prairie et de pins, et en bordure d’un chenal, que s’installent les Épigravettiens de CDP 7. Après leur départ, un incendie au moins affecte cette pinède clairsemée. Ainsi, il apparaît que les environs du massif du Gran Sasso ont enregistré cette amélioration climatique de manière plus nette qu’au nord de l’Europe laissant augurer d’intéressantes perspectives d’étude sur la fin de la période glaciaire dans cette partie des Abruzzes. En conclusion, sont retracés quelques traits majeurs de l’histoire environnementale de la vallée du Gallero depuis le Dernier Glaciaire.
Common and Divergent Features of T Cells from Blood, Gut, and Genital Tract of Antiretroviral Therapy–Treated HIV+ Women
Authors: Xie Guorui , Moron-Lopez Sara , Siegel David A , Yin Kailin , Polos Anastasia , Cohen Jennifer , Greenblatt Ruth M , Tien Phyllis C , Lee Sulggi A , Yukl Steven A , Roan Nadia R 
Published: March 2022

Abstract
T cells residing in mucosal tissues play important roles in homeostasis and defense against microbial pathogens. The gut and female reproductive tract (FRT) are both tolerogenic environments, but they differ in the kinds of foreign Ags they need to tolerate. How these different environments influence the properties of their T cells is poorly understood, but important for understanding women’s health. We recruited antiretroviral therapy–suppressed women living with HIV who donated, within one visit, blood and tissue samples from the ileum, colon, rectosigmoid, endometrium, endocervix, and ectocervix. With these samples, we conducted 36-parameter cytometry by time of flight phenotyping of T cells. Although gut and FRT T cells shared features discriminating them from their blood counterparts, they also harbored features distinguishing them from one another. These included increased proportions of CD69+ T resident memory cells of the T effector memory phenotype, as well as preferential coexpression of CD69 and CD103, on the gut-derived cells. In contrast, CD69+CD103+ T resident memory CD8+ T cells from FRT, but not those from gut, preferentially expressed PD1. We further determined that a recently described population of CXCR4+ T inflammatory mucosal cells differentially expressed multiple other chemokine receptors relative to their blood counterparts. Our findings suggest that T cells resident in different tolerogenic mucosal sites take on distinct properties.
LncRNA GAS5 enhances tumor stem cell-like medicated sensitivity of paclitaxel and inhibits epithelial-to-mesenchymal transition by targeting the miR-18a-5p/STK4 pathway in prostate cancer
Authors: Lu Ting-Ting , Tao Xia , Li Hua-Lei , Gai Ling , Huang Hua , Li Feng 
Published: March 2022

ABSTRACT
The onset of prostate cancer (PCa) is often hidden, and recurrence and metastasis are more likely to occur due to chemotherapy resistance. Herein, we identified downregulated long noncoding RNA (lncRNA) growth arrest-specific 5 (GAS5) in PCa that was associated with metastasis and paclitaxel resistance. GAS5 acted as a tumor suppressor in suppressing the proliferation and metastasis of paclitaxel-resistant PCa cells. GAS5 overexpression in vivo inhibited the tumor growth of xenografts and elevated PCa sensitivity to paclitaxel. Combination of GAS5 and paclitaxel treatment showed great potential in PCa treatment. Moreover, mechanistic analysis revealed a novel regulatory network of GAS5/miR-18a-5p/serine/threonine kinase 4 (STK4) that inhibits epithelial-to-mesenchymal transition (EMT) and enhances tumor stem cell-like-mediated sensitivity to paclitaxel in PCa. These findings provide a novel direction for the development of a potential adjunct to cancer chemotherapy that aims to improve the sensitivity of chemotherapy drugs in PCa.
Evaluation of Multiple-Choice Questions by Item Analysis, from an Online Internal Assessment of 6th Semester Medical Students in a Rural Medical College, West Bengal
Authors: Bhattacherjee Sharmistha , Mukherjee Abhijit , Bhandari Kallol , Rout Arup Jyoti 
Published: March 2022

Background:
Properly constructed single best-answer multiple choice questions (MCQs) or items assess higher-order cognitive processing of Bloom's taxonomy and accurately discriminate between high and low achievers. However, guidelines for writing good test items are rarely followed, leading to generation and application of faulty MCQs.

Materials and Methods:
During lockdown period in 2020, internal assessment was taken through online mode using Google Forms. There were 60 'single response type' MCQs, each consisting of single stem and four options including one correct answer and three distractors. Each item was analyzed for difficulty index (Dif I), discrimination index (DI), and distractor efficiency (DE).

Results:
The mean of achieved marks was 42.92± (standard deviation [SD], 5.07). Dif I, DI, and DE were 47.95± (SD 16.39) in percentage, 0.12± (SD 0.10), and 18.42± (SD 15.35), respectively. 46.67% of the items were easy and 21.66% were of acceptable discrimination. Very weak negative correlation was found between Dif I and DI. Out of total 180 distractors, 51.66% were nonfunctional one.

Conclusion:
Item analysis and storage of MCQs with their indices provides opportunity for an examiner to select MCQs of appropriate difficulty level as per the need of assessment and decide their placement in the question paper.
Knowledge, Awareness, and Practices among Consumers Regarding Trans-Fat
Authors: Khanna Poonam , Goel Sonu , Jain Rachita , Singh Arshdeep , Singh Mahendra Pratap 
Published: March 2022

Introduction:
Processed and preserved food items are the major source of dietary trans fat. Despite various legal provision, public awareness toward trans fats are limited.

Objective:
To examine the awareness of participants about various aspects of trans fats and improving their knowledge through education.

Methods:
A cross sectional pre- and posttest survey was conducted online through a webinar. The questionnaire has 11 questions about trans fats. Received responses were coded. Mean and frequency of continuous data were calculated. Chi-square or t-test were used to find the difference in pre and posttest.

Results:
Eighty five out of 95 participants completed both pre- and posttest. The scores for each question were compared to find out awareness improvement. The question based on FSSAI showed 57% improvement while 50% in case of World Health Organization's REPLACE initiative. The difference of mean score of pretest (7.57 ± 1.8) and posttest (9.22 ± 1.37) was statistically significant.

Conclusion:
Nutrition education and proper labelling of food items can improve the knowledge about food ingredients and food purchasing patterns. Proper enforcement and monitoring of food items labeling guidelines can be recommended.
Association of Conicity Index with Different Cardiovascular Disease Risk Factors among Rural Elderly Women of West Bengal, India
Authors: Ghosh Joyeta , Chaudhuri Debnath , Saha Indranil , Chaudhuri Aditi Nag 
Published: March 2022

Introduction:
In menopause, changes in body fat distribution lead to increasing risk of cardiovascular and metabolic diseases. Therefore, the prediction of cardiovascular disease (CVD) by the presence of risk factors is of importance in elderly women.

Objective:
To find out the conicity index (CI) and its association with different CVD risk factors among rural elderly women of West Bengal.

Materials and Methods:
The study was conducted among 236 rural elderly women, selected randomly from 30 villages of Amdanga block, West Bengal. Components of metabolic syndrome (MS), body fat percentage, different lipid profile fractions, CI, and body mass index (BMI) were measured. Statistical tests were calculated using SPSS software version 20.0. P ≤ 0.05 was considered statistically significant.

Results:
High CI (median 1.25 and interquartile range 1.05–1.45) was found. The proportion of participants with high CI were significantly higher among those with MS (87.95%), waist circumference having 80 cm or more (99.09%), blood pressure having ≥ 130/85 mm of Hg (75.66%), body fat percentage ≥25% (80.14%), and BMI ≥23 (93.18%).

Conclusion:
High prevalence of CI existed among rural elderly women. Significant correlation existed between CI and different CVD risk factors as well as some of the components of MS indicating a possible coexistence of different CVD risks.
“Written Formative Assessments with Peer-Assisted Learning” an Innovative Teaching Program for Postgraduate Students in Community Medicine
Authors: Sabale Rupali , Manapuranth Rukman Mecca , Subrahmanya Saurabha Urmi , Pathak Barsha 
Published: March 2022

Introduction:
There is a paucity of research on conducting written formative assessment with constructive feedback for theory paper writing for postgraduates of Community Medicine in India. The concept of “Written Formative assessments with Peer-Assisted Learning Program” was implemented to improve the first 2 levels of Miller's Pyramid and assess its impact on the summative assessment.

Materials and Methods:
The program was conducted for 2 batches of postgraduate students in the Community Medicine enrolled for the academic session of 2016–2019 and 2017–2020. The written formative assessment was conducted every Saturday for 1 h from August to March month in 2018 and 2019. After each test, answer papers were evaluated by the peer and faculty from the department. Written and oral feedback was given by the peer. After IEC approval, we planned to assess the program's effect on level 1 and level 2 Kirkpatrick's framework. The data were analyzed using SPSS statistical package version 24 (SPSS Inc., Chicago, IL, USA). P < 0.05 was considered statistically significant.

Results:
Total 23 formative written assessments were conducted per year. The proportions of knowledge, comprehension, and analytical type of questions asked were 47%, 32%, and 21%, respectively. The mean attendance rate was 76.28% ±16.4%. There was no statistically significant difference in the average percentage of marks in formative (weekly test) and summative assessment (university final examination). There was a statistically significant positive co-relation of projected mean marks and summative assessment marks with the co-efficient of the determination being 22.6%. There was overall positive feedback of the formative and peer-assisted learning (PAL) from post graduate students.

Conclusions:
Written Formative Assessment with PAL program is one of the effective programs for postgraduate students to gain confidence in writing and presentation skills and to score higher in theory examination.