bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phylogenetic and ecological reevaluation of the order Onygenales
Authors: Kandemir Hazal , Dukik Karolina , de Melo Teixeira Marcus , Stielow J. Benjamin , Delma Fatima Zohra , Al-Hatmi Abdullah M. S. , Ahmed Sarah A. , Ilkit Macit , de Hoog G. Sybren 
Published: May 2022

AbstractThe order Onygenales is classified in the class Eurotiomycetes of the subphylum Pezizomycotina. Families in this order have classically been isolated from soil and dung, and two lineages contain causative agents of superficial, cutaneous and systemic infections in mammals. The ecology and habitat choices of the species are driven mainly by the keratin and cellulose degradation abilities. The present study aimed to investigate whether the ecological trends of the members of Onygenales can be interpreted in an evolutionary sense, linking phylogenetic parameters with habitat preferences, to achieve polyphasic definitions of the main taxonomic groups. Evolutionary processes were estimated by multiple gene genealogies and divergence time analysis. Previously described families, namely, Arthrodermataceae, Ajellomycetaceae, Ascosphaeraceae, Eremascaceae, Gymnoascaceae, Onygenaceae and Spiromastigoidaceae, were accepted in Onygenales, and two new families, Malbrancheaceae and Neogymnomycetaceae, were introduced. A number of species could not be assigned to any of the defined families. Our study provides a revised overview of the main lines of taxonomy of Onygenales, supported by multilocus analyses of ITS, LSU, TUB, TEF1, TEF3, RPB1, RPB2, and ribosomal protein 60S L10 (L1) (RP60S) sequences, combined with available data on ecology, physiology, morphology, and genomics.
The V2 receptor antagonist tolvaptan counteracts proliferation and invasivity in human cancer cells
Authors: Marroncini G. , Anceschi C. , Naldi L. , Fibbi B. , Baldanzi F. , Maggi M. , Peri A. 
Published: May 2022

Abstract
Purpose
Hyponatremia, the most frequent electrolyte alteration in clinical practice, has been associated with a worse prognosis in cancer patients. On the other hand, a better outcome has been related to serum sodium normalization. In vitro studies have shown that low extracellular sodium promotes cancer cells proliferation and invasiveness. Tolvaptan, a selective vasopressin receptor type 2 (V2) antagonist, has been effectively used in the last decade for the treatment of hyponatremia secondary to the Syndrome of Inappropriate Antidiuresis. A few in vitro data suggested a direct role of tolvaptan in counteracting cancer progression, so far. The aim of this study was to evaluate the effect and the mechanism of action of tolvaptan in cell lines from different tumours [i.e. colon cancer (HCT-8), hepatocarcinoma (HepG2), neuroblastoma (SK-N-AS)].

Methods and results
First, we showed that these cell lines express the V2 receptor. Tolvaptan significantly reduced cell proliferation with an IC50 in the micromolar range. Accordingly, reduced levels of cAMP, of the catalytic α subunit of PKA, and a reduced pAKT/AKT ratio were observed. Tolvaptan effectively inhibited cell cycle progression, whereas it induced apoptotis. Furthermore, it reduced cell invasiveness. In particular, anchorage-independent growth and the activity of collagenases type IV were blunted in the three cell lines. Accordingly, tolvaptan counteracted the RhoA/ROCK1–2 pathway, which has a pivotal role in regulating cell movement.

Conclusions
Overall, these findings indicate that tolvaptan effectively inhibits tumour progression in vitro. Further studies should clarify whether the V2 receptor might be considered a possible target in anti-cancer strategies in the future.
One-Step Solvometallurgical Process for Purification of Lithium Chloride to Battery Grade
Authors: Avdibegović Dženita , Nguyen Viet Tu , Binnemans Koen 
Published: May 2022

AbstractThe use of lithium in manufacturing of lithium-ion batteries for hybrid and electric vehicles, along with stringent environmental regulations, have strongly increased the need for its sustainable production and recycling. The required purity of lithium compounds used for the production of battery components is very high (> 99.5%). In this work, a solvometallurgical process that exploits the differences in solubility between LiCl and other alkali and alkaline-earth chlorides and hydroxides in ethanolic solutions has been investigated for the purification of LiCl to battery grade at room temperature. A closed-loop flowsheet based on the green solvent ethanol is proposed for purification of LiCl, a precursor for battery-grade LiOH·H2O. High-purity LiCl solution (> 99.5% Li) could be obtained in a single-process step comprising the simultaneous selective dissolution of LiCl and the precipitation of Mg(OH)2 and Ca(OH)2 using LiOH·H2O in 95 vol% ethanol. However, the analogous process in aqueous solution resulted in impure LiCl (typically less than about 75%).
Graphical Abstract
Proper -colorings of are Bernoulli
Authors: RAY GOURAB , SPINKA YINON 
Published: May 2022

AbstractWe consider the unique measure of maximal entropy for proper 3-colorings of
$\mathbb {Z}^{2}$
, or equivalently, the so-called zero-slope Gibbs measure. Our main result is that this measure is Bernoulli, or equivalently, that it can be expressed as the image of a translation-equivariant function of independent and identically distributed random variables placed on
$\mathbb {Z}^{2}$
. Along the way, we obtain various estimates on the mixing properties of this measure.
Attitudes toward policies to encourage influenza vaccination in long-term care facilities: A national survey of US adults aged 50–80 years
Authors: Johnson Kimson E. , Malani Preeti N. , Kirch Matthias , Solway Erica , Singer Dianne C. , Kullgren Jeffrey T. 
Published: May 2022

AbstractIn October 2017, the National Poll on Healthy Aging surveyed a nationally representative sample of 2,007 adults aged 50–80 years to assess attitudes toward influenza (flu) vaccination policies in long-term care facilities. Support for requiring vaccinations was lowest for visitors. Policy makers can use these findings to develop sustainable vaccination strategies.
Representations of Latinos in a Democratic Party Campaign in the United States: Identity Ownership, Narratives, and Values
Authors: Larrosa-Fuentes Juan S. 
Published: May 2022

AbstractIn the 2016 United States presidential election, candidates Trump and Clinton embraced the demands of certain social groups and in this way, politically and symbolically, chose to “own” the social identities of these groups. Trump decided to attack the Latino community, while Clinton positioned herself as an advocate for this community. This article presents the results of a social narrative analysis of the values that Clinton and her team used to reach out to Latino communities during the 2016 election. The Spanish-language messages produced by the Democratic campaign compose the sample, which includes blog posts, Facebook posts, tweets, and television ads. Clinton’s campaign produced narratives about who the “good Latinos” are and, consequently, the “good immigrants” while at the same time promoting values such as globalism, cosmopolitanism, and multiculturalism. Paradoxically, these narratives and values failed to portray Latinos’ diversity because they left out this community’s historical, social, and cultural complexity.
Sacrificial Fathers and the Death of Their Children: How the Story of Job Challenges the Priestly Tradition
Authors: Awabdy Mark A. , Häner Tobias 
Published: May 2022

AbstractJob’s burnt offerings for his sons and daughters followed by their death (Job 1) resembles the sequence of Aaron’s burnt offerings for himself and his sons followed by the death of his oldest sons (Lev 8–10). Within this common sequence of events, the two stories share a cluster of important, identical lexemes. Although it is not impossible that these features could have resulted unintentionally from a shared scribal culture, the textual evidence is strong enough to indicate that the scribe of Job’s prologue alludes to the priestly inauguration story of Leviticus 8–10. By reading Job after Leviticus, one sees the sharp contrast between the divine silence following Job’s intermediary sacrifices (Job 1:5, 18–19) and the divine response both to Aaron’s and to Nadab and Abihu’s sacrifices (Lev 9:22–10:3). This study clarifies how the story of Job rejects a mechanistic understanding not only of traditional wisdom, but of the Priestly cultic tradition of ancient Israel and Judah.
An Archaeology of Ancient Thought: On the Hebrew Bible and the History of Ancient Israel
Authors: Pioske Daniel 
Published: May 2022

AbstractThe question of how to approach the Hebrew Bible as a source for the histories we write of ancient Israel continues to divide scholars. This study responds to such concerns by pursuing an approach informed by a historicized view of knowledge, or a framework in which the claims we make are understood to be reflective of the eras in which they are realized. What this line of research encourages, I argue, are historical investigations into the underlying modes of knowing that would have contributed to the stories told in the biblical writings. Since knowledge about the past is itself historical, this study contends that it is necessary to situate such claims in time, examining the normative assumptions of an era that establish the parameters by which this knowledge is organized and granted credibility. The epistemic conditions that gave rise to the stories recounted in the Hebrew Bible are as much an object of historical interest, on this view, as the stories themselves for assessments of what evidence they might offer.
The Rise of the Holy Spirit in Sixteenth-Century Kabbalah
Authors: Afterman Adam 
Published: May 2022

AbstractThis article examines the development and transformation of the holy spirit within Jewish mysticism. It begins with a brief analysis of primary trends concerning the holy spirit in biblical, rabbinic, and medieval Jewish texts that served as crucial material for the holy spirit’s ascendence in sixteenth-century Jewish mysticism. Following, it examines the writings of leading Jewish mystics: Moses Cordovero, Elijah de Vidas, and Ḥayyim Vital, who resided in the remote Galilean town of Safed. These luminaries each developed the concept of the holy spirit along a spectrum of pneumatic, fusionary, mystical, and revelatory experiences. Ultimately, they transformed the holy spirit into the peak experience of Jewish mystical life— experienced as prophecy, sanctification, and embodiment. This article highlights an important, yet understudied, Jewish mystical phenomenon.
Artificial-intelligence and sensing techniques for the management of insect pests and diseases in cotton: a systematic literature review
Authors: Toscano-Miranda R. , Toro M. , Aguilar J. , Caro M. , Marulanda A. , Trebilcok A. 
Published: May 2022

AbstractIntegrated pest management (IPM) seeks to minimize the environmental impact of pesticide application, and reduce risks to human and animal health. IPM is based on two important aspects – prevention and monitoring of diseases and insect pests – which today are being assisted by sensing and artificial-intelligence (AI) techniques. In this paper, we surveyed the detection and diagnosis, with AI, of diseases and insect pests, in cotton, which have been published between 2014 and 2021. This research is a systematic literature review. The results show that AI techniques were employed – mainly – in the context of (i) classification, (ii) image segmentation and (iii) feature extraction. The most used algorithms, in classification, were support vector machines, fuzzy inference, back-propagation neural-networks and recently, convolutional neural networks; in image segmentation,k-means was the most used; and, in feature extraction, histogram of oriented gradients, partial least-square regression, discrete wavelet transform and enhanced particle-swarm optimization were equally used. The most used sensing techniques were cameras, and field sensors such as temperature and humidity sensors. The most investigated insect pest was the whitefly, and the disease was root rot. Finally, this paper presents future works related to the use of AI and sensing techniques, to manage diseases and insect pests, in cotton; for instance, implement diagnostic, predictive and prescriptive models to know when and where the diseases and insect pests will attack and make strategies to control them.
Citric acid incorporated in a chitosan film as an active packaging material to improve the quality and duration of matured cheese shelf life
Authors: Ressutte Jéssica Barrionuevo , da Silva Saranti Tascila Ferreira , de Moura Márcia Regina , dos Santos Pozza Magali Soares , da Silva Scapim Mônica Regina , Stafussa Ana Paula , Madrona Grasiele Scaramal 
Published: May 2022

AbstractChitosan-based film incorporated with citric acid was prepared by the casting method for application in a Brazilian matured cheese. Three formulations of cheese were processed, with the intention of evaluating the application of a starter culture and the effect of the film in terms of its physiochemical, microbiological, and sensorial characteristics. It was observed by scanning electron microscopy (sem) analysis that the film has a homogeneous appearance, and the crosslinking between citric acid and chitosan was confirmed by the Fourier transform infrared spectroscopy (FTIR) analysis. The cheese with chitosan-based film presented lower weight loss (5.2%) and showed antimicrobial activity against aerobic mesophilic bacteria. All samples showed high rates of sensorial acceptability (>79%), with no significant differences between them. It is apparent that the chitosan film maintained the typical cheese characteristics. Therefore, chitosan and citric acid film can be used to improve the characteristics of matured cheese and extend its shelf life.
The logical problem of the incarnation: a new solution
Authors: Sijuwade Joshua R. 
Published: May 2022

AbstractThis article aims to provide a new solution to the Logical Problem of the Incarnation by proposing a novel metaphysical reconstrual of the method of reduplicative predication. This reconstrual will be grounded upon the metaphysical thesis of ‘Ontological Pluralism, proposed by Kris McDaniel and Jason Turner, and the notion of an ‘aspect’ proposed by Donald L. M. Baxter. Utilising this thesis and notion will enable the method of reduplicative predication to be further clarified, and the central objection that is often raised against this approach can be successfully answered.
Blanche Evan'sFilm Studies of the Dance: The “Technique Problem” and the Creation of New Forms in 1930s Revolutionary Dance
Authors: Harris Andrea 
Published: May 2022

AbstractThis article examinesFilm Studies of the Dance, a dance film created in 1935 by Blanche Evan, Lionel Berman, and David Wolff. The film premiered Evan's new system of dance training, Functional Technique, to the 1930s New York revolutionary dance community. I analyze the film and Functional Technique inside of the debates over technique and content that preoccupied left-wing modern dancers in this period. Ultimately,Film Studies of the Danceemerges as a collaborative attempt by Evan, Berman, and Wolff to create new approaches to dance and film that would unify form and content to further socially conscious art making.
Effect of perception difference between first- and third-person perspectives on local and global situation recognition in ship handling
Authors: Kato Yuki , Horiguchi Tomoya 
Published: May 2022

AbstractRemote monitoring and control systems are being used with more frequency, but the characteristics of situational awareness and decision-making from remote locations are largely unknown. Remote operators’ sources of information differ from on-board sources greatly in terms of perspective, field of view, and available data type (qualitative or quantitative). This study focused on clarifying the cognitive effects of first- and third-person perspectives on ship handling. A working hypothesis was formulated based on the findings of visual information processing and previous studies and tested using a developed ship handling simulator. The results revealed that: (1) the cognitive characteristics of the first-person perspective make it more effective in safely guiding ship handling than does the third-person perspective, and (2) the deviation in cognitive characteristics is prominent where collision can be easily avoided. The findings will aid the development of on-board and remotely piloted vessels and ensure the safety of their crews.
Global value chains, development and the long duree of trade and investment law
Authors: Alessandrini Donatella 
Published: May 2022

AbstractThis article takes issue with the assumption the policy research literature, specifically that produced by the World Trade Organization (WTO), makes about the role of law as one which is mainly reactive to an exogenous economic reality, that of value chain trade. It argues instead that law has played a much more active role, shaping the so-called fragmentation and fractionalization of production that has led to the proliferation of Global Value Chains (GVCs). By tracing the evolution of post/colonial international economic law, the article shows how trade and investment provisions in particular have been (and still are) an important terrain over which the relationship between companies and states is articulated, with important consequences for all actors involved in GVCs. If this active role is acknowledged then law can be seen not only as contributing, together with other market-making mechanisms, to the making of those economic processes it is assumed to only respond, but also as a means through which these processes can be shaped otherwise.
Epigenetic modifications at DMRs of imprinting genes in sperm of type 2 diabetic men
Authors: Jazayeri Maryam , Eftekhari-Yazdi Poopak , Sadighi Gilani Mohammad Ali , Sharafi Mohsen , Shahverdi Abdolhossein 
Published: May 2022

SummaryHigh rates of infertility in type 2 diabetic (T2DM) men have led to attempts to understand the mechanisms involved in this process. This condition can be investigated from at least two aspects, namely sperm quality indices and epigenetic alterations. Epigenetics science encompasses the phenomena that can lead to inherited changes independently of the genetics. This study has been performed to test the hypothesis of the relationship between T2DM and the epigenetic profile of the sperm, as well as sperm quality indices. This research included 42 individuals referred to the infertility clinic of Royan Institute, Iran in 2019–2021. The study subjects were assigned to three groups: normozoospermic non-diabetic (control), normozoospermic diabetic (DN) and non-normozoospermic diabetic (D.Non-N). Sperm DNA fragmentation was evaluated using the sperm chromatin structure assay technique. The global methylation level was examined using 5-methyl cytosine antibody and the methylation status in differentially methylated regions ofH19,MEST, andSNRPNwas assessed using the methylation-sensitive high-resolution melting technique. The results showed that the sperm global methylation in spermatozoa of D.Non-N group was significantly reduced compared with the other two groups (P< 0.05). TheMESTandH19genes were hypomethylated in the spermatozoa of D.Non-N individuals, but the difference level was not significant forMEST. TheSNRPNgene was significantly hypermethylated in these individuals (P< 0.05). The results of this study suggest that T2DM alters the methylation profile and epigenetic programming in spermatozoa of humans and that these methylation changes may ultimately influence the fertility status of men with diabetes.
Difficulties in finding middle-skilled jobs under increased automation
Authors: Nakamura Hideki 
Published: May 2022

AbstractThis study investigates the labor market under increased automation of middle-skilled jobs wherein worker suitability for these jobs is considered. We examine two effects of increased automation on workers. The first effect is the possibility of replacement of middle-skilled workers by machines. The second effect is the diversity in job mismatch probabilities of workers. If machines perform a worker’s suitable jobs more (or less) than the worker’s unsuitable jobs, then the worker’s job mismatch probability rises (or declines). Because workers who have larger job mismatch probabilities remain job seekers, it is more difficult for a firm to find a suitable worker. Due to these two effects, underemployment rises.
The influence of item order of the Household Food Security Survey Module on the assessment of food insecurity in households with children
Authors: Maia Isabel , Severo Milton , Lopes Carla , Santos Ana Cristina 
Published: May 2022

AbstractObjective:Changes in the item order of the US Household Food Security Survey Module (USHFSSM) were performed throughout time. This study aimed to compare the psychometric properties of the general and specific factors of the 2000 and 2012 versions of the USHFSSM to measure the construct of food insecurity in two Portuguese samples of households with children.Design:Cross-sectional.Setting:Portugal.Participants:An adaptation of the 2000 version was applied to 839 adults (from households with children aged 7–17 years) from the National Food, Nutrition and Physical Activity Survey 2015–2016, while the 2012 version was used among 2855 families from the Generation XXI birth cohort.Results:The 2000 version showed to have a stronger ωh than the 2012 version (0·89 v. 0·78 for the general factor), as well as eigenvalues higher than 1 for the general factor (eigenvalues equal to 9·54, 0·97 and 0·80, for the general factor, specific factor 1 and specific factor 2, respectively), while the 2012 version had also the contribution of specific factors to explain food insecurity (eigenvalues equal to 9·40, 2·40 and 1·20, for general factor and specific factors 1 and 2, respectively). Good internal consistency (ωt = 0·99, for both versions) was obtained.Conclusions:In conclusion, the 2000 and 2012 versions of the USHFSSM showed good psychometric properties; however, the 2000 version has stronger general factor, while the 2012 version also has the contribution of specific factors.
Histopathological Impact of Bleomycin on Lung Injury and Development of Mediastinal Fat-Associated Lymphoid Clusters in the Lymphoproliferative Mouse Model
Authors: Elewa Yaser Hosny Ali , Ichii Osamu , Mohamed Sherif Kh A , Kon Yasuhiro 
Published: May 2022

Abstract
The purpose of this study is to elucidate the impact of bleomycin on the degree of lung injury and development of mediastinal fat-associated lymphoid clusters (MFALCs) in the lymphoproliferative mouse model (MRL/MpJ-Faslpr/lpr “Lpr”) and its control strain (MRL/MpJ “MpJ”). We analyzed immune cells, the degree of proliferation, lymphatic vessels (LVs), and high endothelial venules (HEVs) in lungs and MFALCs in Lpr and MpJ mice on the 7th and 21st days following intranasal instillation of either bleomycin (BLM group) or PBS (PBS group). The BLM group showed a significant increase in the size of MFALCs, lung injury score, and positive area ratios of LVs, HEVs, and immune cells (especially macrophages, B- and T-lymphocytes) on both days 7 and 21. Interestingly, the lungs in the BLM group on day 21 showed higher collagen deposition and cellular infiltration in MpJ and Lpr, respectively. Moreover, significant positive correlations were observed between the size of MFALCs and lung injury. In conclusion, BLM could exert lung fibrosis or lymphoproliferative infiltration in chronic stages in MpJ and Lpr, respectively, and this varied effect could be due to the variations in the degree of immune cell proliferation and the development of LVs and HEVs among the studied strains.