bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reconstructing Recognizable 3D Face Shapes based on 3D Morphable Models
Authors: Jiang Diqiong , Jin Yiwei , Zhang Fang‐Lue , Lai Yu‐Kun , Deng Risheng , Tong Ruofeng , Tang Min 
Published: May 2022

AbstractMany recent works have reconstructed distinctive 3D face shapes by aggregating shape parameters of the same identity and separating those of different people based on parametric models (e.g. 3D morphable models (3DMMs)). However, despite the high accuracy in the face recognition task using these shape parameters, the visual discrimination of face shapes reconstructed from those parameters remains unsatisfactory. Previous works have not answered the following research question: Do discriminative shape parameters guarantee visual discrimination in represented 3D face shapes? This paper analyses the relationship between shape parameters and reconstructed shape geometry, and proposes a novel shape identity‐aware regularization (SIR) loss for shape parameters, aiming at increasing discriminability in both the shape parameter and shape geometry domains. Moreover, to cope with the lack of training data containing both landmark and identity annotations, we propose a network structure and an associated training strategy to leverage mixed data containing either identity or landmark labels. In addition, since face recognition accuracy does not mean the recognizability of reconstructed face shapes from the shape parameters, we propose the SIR metric to measure the discriminability of face shapes. We compare our method with existing methods in terms of the reconstruction error, visual discriminability, and face recognition accuracy of the shape parameters and SIR metric. Experimental results show that our method outperforms the state‐of‐the‐art methods. The code will be released at https://github.com/a686432/SIR.
Microvascular disease increases the risk of lower limb amputation – A Western Danish cohort study
Authors: Olesen Kevin Kris Warnakula , Anand Sonia , Thim Troels , Gyldenkerne Christine , Maeng Michael 
Published: May 2022

AbstractBackgroundPeripheral artery disease is the leading cause of nontraumatic lower limb amputation. Microvascular disease (MVD) increases the risk of lower limb amputation in patients with peripheral artery disease (PAD). We estimated the risk of lower limb amputation associated with MVD and PAD in a Danish cohort.MethodsWe included every resident without previous lower limb amputation in Western Denmark aged 50–75 years on 1 January 2012 and followed them for 7 years. Participants were stratified by MVD and PAD. We estimated adjusted hazard ratios of lower limb amputation using individuals with no MVD and no PAD as reference. We also provide a sex‐specific analysis and estimated the population attributable fraction of the male sex.ResultsWe included 933,597 individuals, of whom 16,741 had MVD only, 18,217 had PAD only and 1,827 had MVD and PAD. Both MVD only (adjusted hazard ratio 3.36, 95% CI 2.98–3.73) and PAD only (adjusted hazard ratio 7.32, 95% CI 6.62–8.08) increased the risk of lower limb amputation separately. Individuals with MVD and PAD had the highest risk of amputation (adjusted hazard ratio 12.27, 95% CI 10.43–14.80). Men had an increased absolute risk of amputation. The population attributable fraction associated with the male sex was 31%.ConclusionsMicrovascular disease and PAD are independently associated with a threefold and sevenfold increase of amputation risk, respectively. Combined, they had an additive effect constituting a 12‐fold amputation risk. The amputation risk was higher in men than women, and 3 in 10 amputations were attributed to the male sex.
Conceptualizing accountability as an integrated system of relationships, governance, and information
Authors: Pilon Marc , Brouard François 
Published: May 2022

AbstractThis article proposes a conceptual framework that integrates the salient dimensions of accountability. It is based on an extensive review of the literature and draws on systems theory to develop an accountability system that can be applied to a wide range of organizations and contexts. It shows, through the accountability system presented, that organizations manage their accountability through stakeholder relationships, governance mechanisms, and information strategies, which are based on underlying values and purposes. This conceptual framework contributes to accountability theory by bridging different yet related concepts and clarifying the terminology used in the literature. Practically, conceptualizing accountability as an interconnected system can help organizations operationalize their accountability management practices. A hospital case study is used to demonstrate the applicability of the accountability system.
Transarterial chemoembolization plus a PD‐1 inhibitor with or without lenvatinib for intermediate‐stage hepatocellular carcinoma
Authors: Xiang Yan‐Jun , Wang Kang , Yu Hong‐Ming , Li Xiao‐Wei , Cheng Yu‐Qiang , Wang Wei‐Jun , Feng Jin‐Kai , Bo Meng‐Han , Qin Ying‐Yi , Zheng Yi‐Tao , Shan Yun‐Feng , Zhou Li‐Ping , Zhai Jian , Cheng Shu‐Qun 
Published: May 2022

AbstractAimTransarterial chemoembolization (TACE) combined with a PD‐1 inhibitor and TACE combined with a PD‐1 inhibitor and lenvatinib have recently been reported as promising treatments to improve the prognosis of hepatocellular carcinoma (HCC) patients. This study aims to compare the efficacy of these two treatments.MethodsA retrospective study was conducted, and patients were recruited from two centers in China. Progression‐free survival (PFS) and overall survival (OS) were compared, and the objective response rate (ORR) and disease control rate (DCR) were evaluated according to the modified Response Evaluation Criteria in Solid Tumors (mRECIST). Treatment‐related adverse events (AEs) were analyzed to assess safety.ResultsThe median follow‐up for the entire cohort was 11.4 months. Of the 103 patients included in this study, 56 received triple therapy, and 47 received doublet therapy. PFS was significantly higher in the triple therapy group than in the doublet therapy group (mPFS 22.5 vs. 14.0 months, P < 0.001). Similar results were obtained in terms of OS (P = 0.001). The ORR and DCR were also better in the triple therapy group (64.3% vs. 38.3%, P = 0.010; 85.7% vs. 57.4%, P = 0.002). The most common AEs in the triple therapy group were decreased albumin (55.3%), decreased platelet count (51.8%) and hypertension (44.6%).ConclusionsThe combination of TACE with a PD‐1 inhibitor and lenvatinib in patients with BCLC stage B HCC might result in significantly improved clinical outcomes with a manageable safety profile compared with TACE with a PD‐1 inhibitor.
Domestic and family violence knowledge and skills: A private mental health service survey of nurses, allied health, and medical clinicians
Authors: Fisher Caroline A. , Jones Sue , Smyth Chloe Brickell , Stokes Lisa , Cairns Gaylyn , Withiel Toni D. 
Published: May 2022

AbstractMental healthcare services have an important role to play in recognizing and responding to domestic and family violence (DFV). This study aimed to evaluate staff knowledge, confidence, and clinical skills in family violence in an Australian private mental healthcare service. The methodology utilized was a cross‐sectional, online survey of clinical staff. In total, 93 clinical staff participated (51 nursing, 37 allied health, and 5 medical), with a 29% response rate. Most clinicians reported working with patients who had disclosed experiencing family violence, but the majority of clinicians (63%) had received no training in the area, with nurses reporting the lowest training levels. Less than 20% reported definitive knowledge of important clinical skills including key family violence indicators, asking about family violence, and responding to disclosures. However, qualitative text response data indicated that many clinicians would provide responses that encompassed best‐practice recommendations. Overall, the results indicated suboptimal clinician family violence knowledge, with further training needed, particularly in nursing staff. Stronger knowledge and skills in social workers and psychologists, relative to nurses, paralleled existing research in a medical hospital sample. The data from the study will be utilized to inform the implementation of a hospital‐wide quality and service improvement project in the area of DFV clinical response.
The relationship between borderline personality disorder and occupational participation: An integrative review
Authors: Larcombe Enara , Müller Amanda 
Published: May 2022

AbstractThis integrative review explores the impact of borderline personality disorder (BPD) symptomology and behaviours on occupational capacity, participation, and sustainability. The disorder has also been associated with lower education levels, higher levels of attrition in tertiary education populations, and low occupational participation and employment rates. Personality traits and symptomology have been found to substantially detract from employability. Articles were identified from CINAHL (Cumulative Index to Nursing and Allied Health Literature), PsycINFO/Ovid, ProQuest, and PubMed databases. The Joanna Briggs’ Institute (JBI) critical appraisal tools were used to evaluate the quality of evidence, and inductive thematic analysis used to extract main themes. Four themes regarding ‘barriers’, ‘enablers’, ‘treatment’, and ‘benefits’ emerged amongst the 11 eligible articles. The negative symptomology was a barrier to occupational participation, and people with BPD engaged in self‐stigmatizing and non‐disclosure. However, the positive symptomology such as boldness and honesty were enablers. Treatment was found to be a key element, and occupational engagement was also found to have positive effectives. The evidence indicates that employment improved the symptoms, and a long‐term treatment plan is a key element. Some upskilling of mental health workers may be required, including a focus on possible positive symptomology as a way of dealing with the stigmatization. Some awareness raising of the disorder, including for employers, may be needed, with education programmes that deal with the stigmatization. Future funding should focus on specialized programmes targeting unemployment for this group.
Prevalence and burden of skin diseases among the elderly in Singapore: a 15‐year clinical cohort study
Authors: Yew Y.W. , Kuan A.H.Y. , George P.P. , Zhao X. , Tan S.H. 
Published: May 2022

AbstractBackgroundPopulations around the world are rapidly ageing. The profile of skin diseases in the elderly is likely to present unique demands on the healthcare system.ObjectivesTo provide current data on the burden of skin diseases in Singaporean patients and identify differences in the pattern of skin diseases between elderly patients and the rest of the population.MethodsThis was a retrospective cohort study of 858 117 patients who attended the National Skin Centre between 2004 and 2018. Prevalence was calculated by grouping International Classification of Diseases codes into different categories of skin conditions based on Global Burden of Disease and American Academy of Dermatology classifications. Years lost to disability (YLDs) and disability‐adjusted life years (DALYs) were calculated to report the morbidity and mortality of skin diseases. Differences of each skin condition between age groups were compared.ResultsThe three most prevalent dermatoses across all age groups were dermatitis (33.3%), acne vulgaris (8.3%) and viral skin diseases (7.5%). The top three most common skin conditions among the elderly were dermatitis (37.7%), viral skin diseases (6.2%) and fungal skin diseases (4.3%). Decubitus ulcers, keratinocyte carcinomas and scabies represented a significant proportion of YLD per 100 000 in the elderly (P < 0.001). Malignant melanomas, keratinocyte carcinomas, cellulitis, pyoderma and decubitus ulcers contributed to high DALYs in patients aged 70–80 years.ConclusionAligning health systems with specific healthcare needs will reduce the disproportionately high burden of skin disease observed in the elderly.
A systematic review onCOVID‐19 vaccination and cosmetic filler reactions: A focus on case studies and original articles
Authors: Kalantari Yasamin , Aryanian Zeinab , Mirahmadi Seyed‐Mohamad‐Sadegh , Alilou Sanam , Hatami Parvaneh , Goodarzi Azadeh 
Published: May 2022

AbstractBackgroundTissue fillers are among the most popular cosmetic procedures performed and notably, cases of filler reactions after COVID‐19 vaccination have been reported.ObjectiveThe objective was to determine the characteristics of patients with filler reaction after COVID‐19 vaccination and address several considerations that have to be taken into practice.MethodsA PRISMA compliant systematic search was conducted in Scopus, Web of Science, and PubMed/MEDLINE databases for articles published from inception up to October 21, 2021.ResultsOut of 106 initially retrieved articles, four of them were included in our study, and a total number of 13 cases were analyzed. In this study, we found that all of the patients who developed delayed‐type reaction (DTR) following COVID‐19 vaccination were middle‐aged women without any known history of allergy to foods or drugs. All patients had a history of hyaluronic acid (HA) filler injection in their head and neck and demonstrated symptoms particularly swelling, from <1 day up to 10 days after the first or second doses of vaccines. Lisinopril, hyaluronidase, and corticosteroids seemed to have good results in management.ConclusionAlthough rare, DTR to fillers after COVID‐19 vaccination can happen. Physicians should be aware of the pathogenesis and management of this phenomenon.
Turkish adaptation of contraceptive knowledge assessment scale and its validity and reliability study in Turkey
Authors: Eryilmaz Mustafa E. , Kuş Celal , Gümüştakim Raziye Ş. 
Published: May 2022

AbstractAimOur study aims to adapt the “Contraceptive Knowledge Assessment‐CKA” questionnaire which is a comprehensive foreign scale to Turkish due to the lack of a scale that is adequately developed in our country regarding contraceptive methods and then to conduct the validity and reliability study of the questionnaire by applying it.MethodsOur study was conducted with individuals who voluntarily participated in the questionnaire and were over 18 years old between April and July 2020. Our study was a methodological one and was designed as a validity and reliability study. Our study included factor analyses for validity analysis, Cronbach alpha, item‐total correlation, test–retest correlation analysis for reliability analysis. In our study, statistical significance was considered as p < 0.05 and SPSS statistical package program was employed for calculations.ResultsIn our study, Kaiser‐Meyer‐Olkin's value was 0.86, and Bartlett's result was p < 0.05. Cronbach alpha was found as 0.86. The correlation analysis of test–retest points was 0.975 (97.5%) with a p‐value 0.000, there was a significant difference.ConclusionsIt was concluded that our study has high reliability and high validity as a result of the questionnaires and analyses performed in this study on the Turkish adaptation of the “CKA” scale developed by Haynes et al.
Dietary fumonisin may compromise the nutritive value of feed and distort copper and zinc digestibility and retention in weaned piglets
Authors: Zeebone Y. Y. , Kovács M. , Bóta B. , Zdeněk V. , Taubner T. , Halas V. 
Published: May 2022

AbstractFumonisins (FUM) have been reported to impede gut functioning in pigs. However, investigations into the possible effect on mineral metabolism are limited. Thus, the trial studied the apparent total tract digestibility (ATTD) and retention of dietary nitrogen and minerals, intestinal architecture, digestive enzymes activity and heat‐shock protein 70 (Hsp70) activity. Eighteen weaned piglets of 7 weeks old were assigned to three groups and their feed either contained 0, 15 or 30 mg FUM/kg for 21 days. ATTD and retention of dietary N and minerals were measured in a 5‐ day long balance trial between Day 17 and Day 21. The digestible and metabolisable energy (DE and ME) content of the feeds were also determined. The body weights, cumulative feed intake, relative organ weights, digestive enzymes activity and intestinal morphology were not affected (p > 0.05) by dietary treatments. The DE content was significantly lower (p < 0.05) when the feed contained 15 mg/kg FUM, but no statistically reliable treatment effect was confirmed for ME content. Dietary FUM significantly lowered (p < 0.05) the ATTD of Ca and P but not (p > 0.05) N, K, Mg and Na. The relative retention rate of N, Ca, P, K, Mg and Na in all groups were not impacted (p > 0.05) by treatments. The ATTD and relative retention of Cu and Zn were remarkably (p < 0.05) lower in piglets fed FUM‐contaminated feed. In addition, the expression of Hsp70 activity in the liver was significantly elevated (p < 0.05) in the highest treatment group. These findings suggest that a dietary dose of 15 or 30 mg FUM/kg diet distorts the nutritive value of the mixed feed, results in poor ATTD and retention rates of Zn and Cu, and elevate Hsp70 activity in the liver without altering intestinal architecture or digestive enzymes' activity in weaned piglets.
Linguistic and Artistic Representations of Trauma: The Contribution of Pedagogies of Discomfort in Language Education
Authors: PORTO MELINA , ZEMBYLAS MICHALINOS 
Published: May 2022

AbstractThis article aims to contribute to recent discussions on pedagogy of pain in world language education. Drawing on the limitations of language to represent and express trauma and pain, we foreground the value of pedagogies at the intersection of language, art, and trauma. It is our contention that a linguistic perspective in and of itself is insufficient and needs to be supported by artistic and multimodal forms of expression as those reinforced by the arts. We describe a study that addressed trauma in a language education context and show how linguistic and nonlinguistic representations of trauma and pain can be productively engaged in formal educational settings using the notion of pedagogy of discomfort. We conclude by highlighting that engaging with the limits of the (un)sayable linked to traumatic and painful events and experiences complementing linguistic with nonlinguistic means can benefit applied linguistics and world language education by bringing attention to the embodied and affective complexities emerging from engagement with trauma.
High‐intensity interval exercise versus moderate‐intensity continuous exercise on postprandial glucose and insulin responses: A systematic review and meta‐analysis
Authors: Khalafi Mousa , Mojtahedi Shima , Ostovar Alireza , Rosenkranz Sara K. , Korivi Mallikarjuna 
Published: May 2022

SummaryWe performed a meta‐analysis to investigate the effects of high‐intensity interval exercise (HIIE) as compared to moderate‐intensity exercise (MIE) and a control condition (CON) on postprandial glucose (PPG) and insulin (PPI) responses. PubMed, Web of Science, and Scopus were comprehensively searched to identify relevant studies until October 2021. Separate analyses were conducted for HIIE versus MIE and HIIE versus CON. A total of 30 studies comprising 36 intervention arms and involving 467 participants (350 adults) were included in the meta‐analysis. HIIE reduced PPG and PPI when compared with CON. Based on subgroup analyses, reductions in PPG and PPI were significant for both children and adult participants, as well as for healthy participants and participants with metabolic disorders, with larger effects in those with metabolic disorders. There were no significant differences between HIIE and MIE for PPG or PPI. However, when comparing studies matched for total work performed, HIIE was more effective for decreasing PPG as compared with MIE. HIIE is effective for reducing PPG and PPI in both children and adult participants, particularly in those with metabolic disorders. In addition, HIIE has superior effects for reducing PPG as compared with MIE, when equivalent work was performed at both intensity levels.
Shared genetic components between metabolic syndrome and schizophrenia: Genetic correlation using multipopulation data sets
Authors: Aoki Rei , Saito Takeo , Ninomiya Kohei , Shimasaki Ayu , Ashizawa Takuma , Ito Kenta , Ikeda Masashi , Iwata Nakao 
Published: May 2022

AimThe genetic relationship between schizophrenia (SCZ) and other nonpsychiatric disorders remains largely unknown. We examined the shared genetic components between these disorders based on multipopulation data sets.MethodsWe used two data sets for East Asian (EAS) and European (EUR) samples. SCZ data was based on the Psychiatric Genomics Consortium Asia with our own genome‐wide association study for EAS and Psychiatric Genomics Consortium for EUR. Nonpsychiatric data (20 binary traits [mainly nonpsychiatric complex disorders] and 34 quantitative traits [mainly laboratory examinations and physical characteristics]) were obtained from Biobank Japan and UK Biobank for EAS and EUR samples, respectively. To evaluate genetic correlation, linkage disequilibrium score regression analysis was utilized with further meta‐analysis for each result from EAS and EUR samples to obtain robust evidence. Subsequent mendelian randomization analysis was also included to examine the causal effect.ResultsA significant genetic correlation between SCZ and several metabolic syndrome (MetS) traits was detected in the combined samples (meta‐analysis between EAS and EUR data) (body mass index [rg = −0.10, q‐value = 1.0 × 10−9], high‐density‐lipoprotein cholesterol [rg = 0.072, q‐value = 2.9 × 10−3], blood sugar [rg = −0.068, q‐value = 1.4 × 10−2], triglycerides [rg = −0.052, q‐value = 2.4 × 10−2], systolic blood pressure [rg = −0.054, q‐value = 3.5 × 10−2], and C‐reactive protein [rg = −0.076, q‐value = 7.8 × 10−5]. However, no causal relationship on SCZ susceptibility was detected for these traits based on the mendelian randomization analysis.ConclusionOur results indicate shared genetic components between SCZ and MetS traits and C‐reactive protein. Specifically, we found it interesting that the correlation between MetS traits and SCZ was the opposite of that expected from clinical studies: this genetic study suggests that SCZ susceptibility was associated with reduced MetS. This implied that MetS in patients with SCZ was not associated with genetic components but with environmental factors, including antipsychotics, lifestyle changes, poor diet, lack of exercise, and living conditions.
From data to knowledge – big data needs stewardship, a plant phenomics perspective
Authors: Arend Daniel , Psaroudakis Dennis , Memon Junaid Altaf , Rey‐Mazón Elena , Schüler Danuta , Szymanski Jedrzej Jakub , Scholz Uwe , Junker Astrid , Lange Matthias 
Published: May 2022

SUMMARYThe research data life cycle from project planning to data publishing is an integral part of current research. Until the last decade, researchers were responsible for all associated phases in addition to the actual research and were assisted only at certain points by IT or bioinformaticians. Starting with advances in sequencing, the automation of analytical methods in all life science fields, including in plant phenotyping, has led to ever‐increasing amounts of ever more complex data. The tasks associated with these challenges now often exceed the expertise of and infrastructure available to scientists, leading to an increased risk of data loss over time. The IPK Gatersleben has one of the world's largest germplasm collections and two decades of experience in crop plant research data management. In this article we show how challenges in modern, data‐driven research can be addressed by data stewards. Based on concrete use cases, data management processes and best practices from plant phenotyping, we describe which expertise and skills are required and how data stewards as an integral actor can enhance the quality of a necessary digital transformation in progressive research.