bluuebunny/crossref_metadata_2025_split huggingface dataset:
Innovative GACP Approaches for Obtaining the QualityIris hybridaLeaves for the Pharmaceutical Industry
Authors: Mykhailenko Olha , Buydin Yrii , Ivanauskas Liudas , Krechun Anastasia , Georgiyants Victoriya 
Published: March 2022

AbstractThe ever‐growing demand for active compounds of plant origin contributes to the implementation of cultivation methods for medicinal plants, according to the WHO guideline “Good Agricultural and Collection Practice (GACP) for Starting Materials of Herbal Origin” to obtain high‐quality raw material with the stable phytocomponent composition. Therefore, the development of the cultivation and processing stages ofIrisvarieties leaves is necessary and promising. The present article showed the potential of proper cultivation with GACP recommendations on affecting the phenolic compounds content inIris×hybridahort. ‘Indian Pow Waw’,Iris×hybridahort. ‘Galleon Gold’, andIris×hybridahort. ‘Mini Dinamo’ leaves. The cultivation process was carried out on the experimental sites of the flowering and ornamental plants department of M.M. Hryshko National Botanical Garden of the National Academy of Sciences of Ukraine (Kyiv, Ukraine) during 2018–2021. A positive effect ofIrissamples proper cultivation and content of isoflavonoids (tectoridin, nigricin D‐glucoside, genistin, iristectorigenin B, nigricin, irigenin, irisolidone), xanthone mangiferin, and also chlorogenic acid inIrisesleaves by HPLC has been established. According to the analysis mangiferin (7.57∼28.75 μg/g), genistin (3324.82∼14642.10 μg/g), irisolidone (673.53∼2015.81 μg/g), and irigenin (3904.37∼1595.94 μg/g) were the dominant components and these compounds can be proposed as chemical markers forIrisraw material. The obtained results indicate a significant positive effect of the introduction and observance of the proper cultivation of medicinal plants to obtain a stable bioactive compounds content, in this case, on the example ofIrisgenus plants. Further work on the implementation of the good practice recommendation is planned to be carried out for various medicinal plants, since only controlled cultivation makes it possible to obtain high‐quality raw materials with a standardized composition.
Cutaneous manifestations of COVID‐19 among healthcare workers: A Case report and literature review
Authors: Imen Youssfi , Mechergui Najla , Litaiem Noureddine , Youssef Imen , Gara Soumaya , Zeglaoui Faten , Rammeh Soumaya , Ladhari Nizar 
Published: March 2022

AbstractCommon clinical features of COVID‐19 are increasingly known but cutaneous manifestations are rarely described among healthcare workers. A review of cutaneous manifestations of COVID‐19 especially among healthcare workers (HCW) is thus required. The aim of our current study was to provide a comprehensive review of cutaneous manifestations of COVID‐19 among HCW through six case reports and a literature review. We conducted a literature search for cases reports, original and review articles using PubMed and the Google search engines. We included the written English studies that mentioned cutaneous symptoms during COVID‐19 infection. In addition to the review, 6 cases were collected among the HCW working at the Charles Nicolle Hospital of Tunis from September 2020 to January 2021. In our review, we included 17 articles in addition to our six cases. The type of papers was case series and case reports in respectively 8 and 9 studies. Skin manifestations were reported in two studies including two HCW, in addition to our series of six HCW. Skin manifestations were chilblain‐like lesions (44.5%), a generalized macular or maculopapular exanthem (32.1%), a papulovesicular rash and chicken pox‐like vesicles (11.5%), painful acral red–purple papules (4.6%), urticaria (2.8%), purpuric or petechial lesions (2.3%), and livedo reticularis lesions (0.45%). Of the 218 cases, 203 cases have reported the location of lesions. The very great majority of lesions were found on the trunk, hands, and feet. Fifty‐one patients (23.4%) experienced lesions on the trunk. The time of onset of cutaneous lesions was variable. At the diagnosis or the onset of COVID‐19 symptoms, 8.3% (18/218) of patients presented with cutaneous lesions. After the onset of respiratory symptoms or COVID‐19 diagnosis, 36.7% (80/218) of patients presented with cutaneous lesions. Of the 197 cases with reported healing times, healing times were up to 24 days. COVID‐19 has been associated with different cutaneous manifestations, likely of varying pathophysiology and severity, some preceding COVID‐19 symptomatology and others occurring during active disease or later in the course. Thus, heightened awareness and timely recognition of cutaneous manifestations in COVID‐19 are important for occupational physicians treating HCW with COVID‐19.
Spraying Characteristics of Alcohol‐Coal‐Water Slurries with Low Coal Content
Authors: Gvozdyakov Dmitry , Zenkov Andrey , Lavrinenko Sergey , Marysheva Yana , Larionov Kirill 
Published: March 2022

AbstractThe results of spraying characteristics of alcohol‐coal‐water slurries are presented. It has been experimentally proved that the lowest viscosity value of the studied slurries varies from 54 to 329 mPa s. The density value of alcohol‐coal‐water slurries decreases to 1130 kg m−3 when the content of isopropyl alcohol in the fuel composition is 8 wt %. The largest value of jet spraying angle corresponds to alcohol‐coal‐water fuel with an isopropyl alcohol content of 8 wt %. The number of sufficiently large droplets decreases in comparison with a typical two‐component coal‐water fuel. The calorific value of alcohol‐coal‐water slurries rises when the third liquid fuel component is introduced into the composition of coal‐water fuel.
A Flow Electrochemical Cell with Split Bipolar Electrode for Anodic Oxidation of Organic Compounds
Authors: Sakagami Hiroki , Takenaka Hiroaki , Iwai Suguru , Shida Naoki , Villani Elena , Gotou Akihiro , Isogai Tomohiro , Yamauchi Akiyoshi , Kishikawa Yosuke , Fuchigami Toshio , Tomita Ikuyoshi , Inagi Shinsuke 
Published: March 2022

AbstractThe recent development of flow electrochemical reactors has been remarkable, but efforts are still required to reduce the amount of supporting electrolyte used in electrosynthesis. To address this problem, herein an advanced process combining flow reactors and bipolar electrochemistry is proposed. The developed electrochemical system was successfully employed for the anodic fluorination and anodic coupling of organic compounds using low concentration of supporting electrolytes. Such combined electrochemical system would represent a promising electrosynthesis method toward green and sustainable chemistry.
NaWuReT Colloquium: From PhD Student to Assistant Professor – Early Career Chemical Engineers in Academia
Authors: Friedland Jens , Börnhorst Marion , Kreitz Bjarne , Moioli Emanuele , Wehinger Gregor 
Published: March 2022

AbstractThe Nachwuchs Reaktionstechnik (NaWuReT) are early‐career scientists from the ProcessNet Division Reaction Engineering. In autumn 2021, they organized an online colloquium with international early‐career scientists from the chemical engineering community. Five guests were invited to give a scientific talk and provide insights into their career paths. The guests gave advice and emphasized the main challenges and opportunities during their early careers. Crucial points are networking, guidance, mentoring, as well as funding acquisition and the personal work‐life balance.
Parcellation of the murine cortical hindlimb area is demonstrated by its subcortical connectivity and cytoarchitecture
Authors: Kameda Hiroshi , Murabe Naoyuki , Mizukami Hiroaki , Ozawa Keiya , Hayashi Toshihiro , Sakurai Masaki 
Published: March 2022

AbstractAlthough corticospinal neurons are known to be distributed in both the primary motor and somatosensory cortices (S1), details of the projection pattern of their fibers to the lumbar cord gray matter remain largely uncharacterized, especially in rodents. We previously investigated the cortical area projecting to the gray matter of the fourth lumbar cord segment (L4) (L4 Cx) in mice. In the present study, we injected an anterograde tracer into multiple sites to cover the entire L4 Cx. We found that (1) the rostromedial part of the L4 Cx projects to the intermediate and ventral zones of the lumbar cord gray matter, (2) the lateral part projects to the medial dorsal horn, and (3) the caudal part projects to the lateral dorsal horn. We also found that the border between the rostromedial and caudolateral parts corresponds to the border between the agranular and granular cortex. Analysis of the somatotopic patterns formed by the cortical projection cells and the primary sensory neurons innervating the skin of the hindlimb and its related area suggests that the lateral part corresponds to the S1 hindlimb area and the caudal part to the S1 trunk area. Examination of thalamic innervation by the L4 Cx revealed that the caudolateral L4 Cx focally projects to the ventrobasal complex (VB) and the posterior complex (PO), while the medial L4 Cx widely projects to the PO but little to the VB. These findings suggest that the L4 Cx is parceled into subregions defined by the cytoarchitecture and subcortical projection.
Elderly Hajj pilgrims activity recognition based on candidate classification technique
Authors: B A Mohammed Hashim , R Amutha 
Published: March 2022

AbstractEvery year, the rate of elderly people is rising, and monitoring them in mass gatherings like a pilgrimage is a tough task. Millions of Muslims around the world visit Makkah and Madinah for the Hajj pilgrimage. Since 1990, more than 4800 pilgrims have died in the stampede. Aged pilgrims are very much vulnerable to these stampedes. To support them, it is very important to monitor their activities. But only a little is done to monitor the elderly pilgrims. In this article, all the rituals performed in the Hajj pilgrimage have been studied and an activity recognition dataset for elderly pilgrims in line with the rituals of Hajj has been created. A novel classification method called the candidate classification technique (CCT) is proposed to recognize the activities accurately with less response time. Three publicly available activity recognition datasets namely UCI HAR, USC HAD, SKODA, and the proposed elderly hajj pilgrim activity recognition dataset have been used. The accuracy achieved using the proposed classification technique is 98.25%, 96.97%, and 99.29% for the UCI HAR, USC HAD, and SKODA datasets.
Sudden gains and treatment outcomes among depressed individuals in a partial hospitalization programme
Authors: Terrill Douglas R. , Levin‐Aspenson Holly , Zimmerman Mark 
Published: March 2022

AbstractSudden gains commonly occur among patients receiving psychotherapy for depression and have been found to consistently predict better treatment outcomes. However, the majority of prior research has examined sudden gains primarily in weekly or biweekly treatment settings. Individuals were divided into two groups: those who experienced at least one sudden gain and those who did not. Rates of sudden gain occurrence, pretreatment factors and posttreatment outcomes were examined between the two groups. Over 60% of this sample experienced at least one sudden gain, the majority of which occurred during the first 3 days of treatment. Sudden gains were associated with significantly lower baseline depression and anxiety severity. Patients who experienced sudden gains reported significantly greater improvement in depressive and anxiety symptoms, coping skills, functioning, positive mental health and well‐being at treatment termination. This study was conducted in a single location with a relatively homogeneous sample. Due to a lack of follow‐up data, we were unable to determine if treatment outcomes were sustained after treatment termination. The assessment timeline of the depressive symptoms differs between baseline and daily scales, which may have affected the number of observed sudden gains after the initial treatment day. The proportion of sudden gains in this study is higher than those found in outpatient settings, demonstrating that this phenomenon may commonly occur among depressed patients in acute treatment. These results suggest that the mechanisms by which sudden gains occur may be reinforced by daily, intensive treatment.
Hierarchical Carbon Composites for High‐Energy/Power‐Density and High‐Reliability Supercapacitors with Low Aging Rate
Authors: Chen Cheng‐Chia , Kirana Nindita , Puspita Daniel Fajar , Patra Jagabandhu , Hsieh Chien‐Te , Gandomi Yasser Ashraf , Lai Hong‐Zheng , Chang Tseng‐Lung , Tseng Chung‐Jen , Majumder Subhasish Basu , Wang Cheng‐Yu , Chang Jeng‐Kuei 
Published: March 2022

AbstractA facile method for preparing hierarchical carbon composites that contain activated carbon (AC), carbon nanospheres (CNSs), and carbon nanotubes (CNTs) for use as the electrode material in supercapacitors (SCs) was developed. The CNS/CNT network enabled the formation of three‐dimensional conducting pathways within the highly porous AC matrix, effectively reducing the internal resistance of an SC electrode. The specific capacitance, cyclability, voltage window, temperature profile during charging/discharging, leakage current, gas evolution, and self‐discharge of the fabricated SCs were systematically investigated and the optimal CNS/CNT ratio was determined. A 2.5 V floating aging test at 70 °C was performed on SCs made with various hierarchical carbon electrodes. Electrochemical impedance spectroscopy, postmortem electron microscopy, Raman spectroscopy, X‐ray diffraction, and X‐ray photoelectron spectroscopy analyses were conducted to examine the electrode aging behavior. A hierarchical carbon architecture with an appropriate AC/CNS/CNT constituent ratio could significantly improve charge‐discharge performance, increase cell reliability, and decrease the aging‐related degradation rate.
Where the wild beavers are: Climate and landscape controls on beaver pond area in snow‐dominated rangeland headwaters
Authors: Fitch Kyle , Nippgen Fabian , Albeke Shannon E. , Paige Ginger B. 
Published: March 2022

AbstractBeavers are of increasing interest as a mechanism for ecosystem restoration. However, the physical watershed characteristics that allow for successful beaver re‐establishment are not consistent across habitat suitability models. We delineated the extent of beaver impounded surface water in the Pole Mountain Area (PMA) of south‐eastern Wyoming with six National Agricultural Imagery Program acquisitions over an 18‐year time period via a random forest classification algorithm. We computed beaver pond area for first‐ and second‐order watersheds within the PMA and related the impounded pond area to climatic metrics such as maximum annual snow water equivalent and snowmelt and rain input into the ground. There was no apparent relationship between annual climate metrics and beaver pond area. Further, we developed a random forest regression model to correlate beaver pond area with topographically derived watershed characteristics (e.g. hillslope size and riparian area size) to explore physical controls on impounded area at the watershed scale. Controls differed for first‐ and second‐order watersheds, with pond area in smaller watersheds largely being controlled by lateral water contributions from the hillslopes and in the larger watersheds by water from upstream and available space in the riparian areas. Interestingly, vegetation height did not emerge as an important predictor for pond area, likely because of generally good availability of forage material in all watersheds. This study improves our understanding of watershed characteristics that contribute to beaver habitat suitability and can be used to guide beaver reintroduction efforts through analysis targeted at identifying watersheds most appropriate to beaver pond construction.
Influence of landscape homogenization due to river damming on dragonfly (Odonata) community structuring in a subtropical forest in the southern Atlantic Forest
Authors: Araujo Breno R. , Pinto Ângelo P. , Padial Andre A. 
Published: March 2022

AbstractHuman activities affect the structure, dynamics and energy flow of aquatic ecosystems. River damming, a common anthropic impact in Brazil, changes solar incidence, water flow and temperature of waterbodies, thereby affecting their fauna. Due to their high sensitivity to environmental changes, the Odonata may be indicators of these impacts. We sampled two ecologically distinct sites, (1) a quasi‐pristine forested area and (2) a nearby human‐impacted reservoir landscape, to evaluate the effects of damming on odonate community structure. The species composition of quasi‐pristine communities was more heterogeneous and differed almost completely (indicating high turnover) from that of the reservoir‐area communities. The capacity of the reservoir to maintain local fauna was almost nil. The communities in the changed landscape had the highest local diversity, which is related to the high occurrence of widespread generalist South American species. We also tested two recently proposed bioindication ratio tools based on the richness or abundance of high‐level taxonomic categories; both effectively reflected the extent of the impacts of damming. The best performing ratios were Coenagrionidae/other Zygoptera richness ratio, Zygoptera/Anisoptera abundance ratio and Libellulidae/other Anisoptera richness ratio. The reservoir landscape promotes biotic homogenization. However, the water supply system entails the preservation of part of the native habitat in its surrounding areas, consequently maintaining forest‐dependent biodiversity in quasi‐pristine environments.
Europium (II) Sulfate EuSO4: Synthesis Methods, Crystal and Electronic Structure, Luminescence Properties
Authors: Denisenko Yuriy G. , Sedykh Alexander E. , Oreshonkov Aleksandr S. , Molokeev Maxim S. , Azarapin Nikita O. , Sal'nikova Elena I. , Chimitova Olga D. , Andreev Oleg V. , Razumkova Illaria A. , Müller‐Buschbaum Klaus 
Published: March 2022

AbstractIn the present work, we report on the synthesis of EuSO4 powders by two different methods using EuS as starting material. The compound EuSO4 contains divalent europium and crystallizes in the orthorhombic crystal system, space group Pnma with parameters close to SrSO4. The compound exhibits near isotropic thermal expansion over the temperature range 300–700 K. EuSO4 was examined by Raman, Fourier‐transform infrared absorption and luminescence spectroscopy methods. EuSO4 is found to be an indirect bandgap material with a bandgap close to direct electronic transition. The emission lifetime of divalent europium d‐f emission in EuSO4 shows an unusual behavior for stoichiometric compounds, as it shortens upon cooling from 1.11(1) μs at room temperature to 0.44(1) μs at 77 K.
Activation of translocator protein alleviates mechanical allodynia and bladder dysfunction in cyclophosphamide‐induced cystitis through repression of BDNF‐mediated neuroinflammation
Authors: Huang Yong , Su Minzhi , Zhang Chi , Zhan Hailun , Yang Fei , Gao Zhentao , Zhou Xiangfu , Liu Bolong 
Published: March 2022

AbstractBackgroundBladder pain syndrome/interstitial cystitis (BPS/IC) is a refractory disease accompanied by bladder‐related pain and hyperactivity. Studies have shown that the translocator protein (TSPO) modulates neuroinflammation and central sensitisation associated with pain. Moreover, we previously demonstrated that brain‐derived neurotrophic factor (BDNF) regulates neuroinflammation and mechanical allodynia in cyclophosphamide (CYP)‐induced cystitis through activation of glial cells. Here, we aimed to explore whether activation of TSPO attenuates mechanical allodynia and bladder dysfunction by regulating BDNF induced neuroinflammation in a CYP‐induced cystitis model.MethodsInjection of CYP was performed to form a rat model of BPS/IC. The expression of TSPO was regulated by intrathecal injection of the TSPO agonist Ro5‐4864. The von Frey filament test was applied to evaluate suprapubic allodynia. Bladder function was assessed using filling cystometry. Western blotting was used to detect the expression of TSPO, BDNF, GFAP, Iba‐1, p‐p38, p‐JNK, TNF‐α, and IL‐1β, and double immunofluorescence was performed to localise TSPO in the L6–S1 spinal dorsal horn (SDH).ResultsTSPO was activated in the SDH after CYP injection and was primarily colocalised with astrocytes. Ro5‐4864 reversed mechanical allodynia and bladder dysfunction induced by CYP. Moreover, the upregulation of BDNF and activation of astrocytes and microglia was suppressed by Ro5‐4864, resulting in downregulation of p‐p38, p‐JNK, TNF‐α, and IL‐1β.ConclusionsRo5‐4864 alleviated mechanical allodynia and bladder dysfunction in the CYP model, possibly by inhibiting the elevation of BDNF and consequent activation of astrocytes and microglia induced neuroinflammation. TSPO may be a potential target for the treatment of BPS/IC.SignificanceThis study examined the mechanism underlying the ability of the translocator protein to modulate bladder pain syndrome/interstitial cystitis.
Heat transfer intensification with field synergy principle in a fin‐and‐tube heat exchanger through convex strip installation
Authors: Syaiful  , Wicaksono Taufan Anindhito , Tony S. U. M. S. K. , Suprihanto Agus , Soetanto Maria F. 
Published: March 2022

AbstractImprovement of heat transfer using surface protrusion (convex strip) has been effective recently. Surface protrusion is able to improve flow mixing which increases the rate of heat transfer. Therefore, this study aims to improve the heat transfer in a fin‐and‐tube heat exchanger by fitting convex strips around the tubes. Three‐dimensional modeling was carried out by placing four and eight convex strips around the staggered tubes at a constant temperature of 106°C. The turbulent k–ɛ model was applied at a Reynolds number range of 3438–15,926. The results of the study indicate that tubes with eight convex strips demonstrated a heat transfer improvement of 40.46%, compared to that with four convex strips. In this case, the TEF is 6.27% higher than the four convex strips. In addition, the synergy angle in the eight convex strips configuration was 0.13% lower than that of the four convex strips configuration. Meanwhile, the flow resistance in the tubes with eight convex strips configurations was 30.96% higher than that of the four convex strips.
A new method of hybrid optimization of small cell range development and density for energy efficient ultra‐dense networks
Authors: Sidiq Sumina , Sheikh Javaid A. , Mustafa Farhana , Malik Bilal A. 
Published: March 2022

AbstractUltra‐dense networks (UDNs) which comprise of small and macro cells, are considered the principal solution for increasing demands of data. However, making energy efficient networks will be a challenge for researchers. In this article, a hybrid optimization technique is proposed to enhance the energy efficiency (EE) of the UDNs, considering the user correlation and hybrid optimization of the density and transmitting power of the small‐cell‐base‐station (SBS). More precisely, the problem framed is a problem of convex‐linear programming and hence is divided into two sub‐problems: cell correlation and hybrid optimization. The expression for the EE of the system is derived in the closed‐form as a factor of the density of SBSs and small cell‐range‐development (CRD) bias dependent on the Poisson point process (PPP) followed by the sequential‐search‐algorithm to improve the small CRD bias and SBS density correspondingly. Additionally, to realize hybrid optimization of the small CRD bias and density of SBSs, a heuristic algorithm is put forward to accomplish the EE of the system. It is revealed from the simulation outcomes that the proposed small CRD bias and SBS density hybrid optimization significantly enhances the EE of the system with low computational intricacy.