bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between COVID-19 infection and ABO and Rh blood group systems
Authors: DAMAR ÇAKIRCA Tuba , BAL Tayibe 
Published: December 2022

Purpose: The aim of this study was to determine whether there is a relationship between COVID-19 infection and ABO and Rh blood groups.
Materials and Methods: 1360 patients with positive SARS-CoV-2 RNA test between April 2020 and March 2022 and 80219 healthy controls whose blood groups were determined before March 2020 were included in this study. Patients were classified according to disease severity as mild, moderate, severe and critical.
Results: Patient and control groups were matched in terms of age and gender using case-control matched method. 1360 patients and 1161 controls were included in the analysis. Of the patients, 42.1% (n=572) had mild, 41.5% (n=564) moderate, 13.8% (n=187) severe and 2.7% (n=37) critical course of infection. It was observed that patients with blood group A were 1.33 times more at risk (OR: 1.33, 95%Cl: 1.12-1.56) for the development of COVID-19 infection compared to patients with other blood groups. No relationship was found between ABO and Rh blood groups and severe-critical COVID-19 disease, need for intensive care and mortality. However, when patients are divided into two groups as mild and non-mild (moderate, severe, critical); the frequency of having O and B blood groups was found to be significantly higher in non-mild cases than in mild cases ( (53.3% and 46.7%), (64.5% and 35.5%, respectively).
Conclusion: In our study, while A blood group was found to be at risk for the development of COVID-19 infection, no relationship was found between Rh blood groups and susceptibility to the disease. In addition, the rate of O and B blood groups was found to be higher in patients who did not have mild disease.
Molecular investigation of mechanisms considered to cause preterm premature membrane rupture
Authors: DEMİR Süleyman Cansun , ARSLAN Erol , ILGAZ Nermin Seda , ÖKSÜZ Hale , ÖZPAK Lütfiye , YILMAZ Mehmet Bertan , AKCABAY Çiğdem 
Published: December 2022

Purpose: The aim of this study was to investigate the mRNA expression level of p16, CDK4, CDK6, Cyclin D, RB1, and E2F genes in preterm premature rupture of membrane (PPROM) cases and their roles in etiopathogenesis of PPROM.
Materials and Methods: Twenty-one pregnancies with PPROM before 34th gestational weeks (study group) were compared with twenty pregnancies with no complication, who gave birth after 37th gestational-week (control group). Both groups chorioamniotic membranes were compared for mRNA expression of p16, cyclin D, CDK4, CDK6, RB1 and E2F genes.
Results: The mRNA expression levels of p16, cyclin D, CDK4, CDK6, RB1and E2F genes decreased in the PPROM group compared to control group at a statistically significant level.
Conclusion: Our findings have shown that oxidative stress may not act on the p16 pathway in these cases. In order to understand the molecular mechanism of PPROM, biomarkers of oxidative stress and aging should be evaluated together with other pathways related to aging and oxidative stress in future studies.
Effect of folic acid supplementation on mental health in the antenatal and postnatal period
Authors: BAL Zeynep , KARSLIOĞLU Gülsüm , UÇAR Tuba 
Published: December 2022

Purpose: The aim of the study was to examine the mental health outcomes of folic acid (FA) supplement use in the antenatal and postnatal periods.
Materials and Methods: This descriptive-prospective longitudinal study was conducted between 1 December 2019 and 30 January 2021 in a Family Health Center in eastern Turkey. The study was performed at one week in the postpartum period, at 6-8 weeks in the postpartum period, and at six months in the postpartum period. A total of 162 healthy pregnant women were included in the study. A Personal Information Form, the Beck Anxiety Inventory (BAI), and the Edinburgh Postpartum Depression Scale (EPDS) were used to collect data.
Results: While 32.7% (n=53) of the participants used FA supplementation from the pre-pregnancy period and in the first trimester of pregnancy (6 months in total), and 34.6% (n=56) used FA supplementation only in the first trimester of pregnancy. It was determined that 32.7% (n=53) of the participants did not use any FA supplement. Of those who did not use FA, 37.0% were in the antenatal period, and 50.8% were on the postnatal 6-8 days. It was determined that the participants experienced mild/moderate/severe anxiety in different weeks. BAI and EPDS scores were the lowest in the prenatal period, at 6-8 weeks in the postpartum period, and at 6 months in the postpartum period in those who used FA supplementation for 6 months. BAI and EPDS scores decreased significantly from the antenatal, to the postnatal 6-8-week, and to the postnatal 6-month measurements.
Conclusion: The use of FA supplements can be effective in preventing symptoms of anxiety and depression in the antenatal and postnatal period.
Assessment of Personal Hygiene Attitudes among Primary School Pupils in Umbada Locality, Khartoum state (2018-2020), Sudan
Authors: Essa Mariam Saeed Ibrahim , Abdalmajed M.A. 
Published: December 2022

Background: Personal hygiene is the behaviors that must be practiced in daily life, starting from morning to sleep time to protect our health.
Objectives: The current study aimed to assess personal hygiene attitudes among Primary School Pupils in Umbada Locality, Khartoum state, Sudan (2018-2020).
Materials and methods: An observational interventional study was conducted besides a pre- & post-assessment was done. Pre-test and post-test intervention was used to determine the practices of hygiene among primary school Pupils in some selected schools of Umbada locality Alaemir unit. The targeted populations were primary school Pupils in Government schools only. The study populations were the pupils in the Primary public schools by a total number of 37850 Pupils (grade 5, grade 6 and grade7) distributed among 180 public primary schools in the locality. The sample size consisted of (800) pupils during the period of the study. A pre- and post- questionnaire was carefully prepared, tested and directed to the pupils. It covers pupil’s age, sex, and the classroom., source of water supply and latrine in the house there, and to obtain data regarding knowledge, attitudes, and practices (as regards personal hygiene in both pre and post intervention phases. Data was analyzed using Statistical Package for Social Sciences SPSS Computer Program Version (19.0).
Results: The study revealed that the overall attitude of pupils, about personal hygiene was increased from 45.8% to 54.2 % after intervention of health education sessions.
Conclusion: Health education has a significant role in promoting attitude of school pupils regarding personal hygiene. The need for more health education concerning personal hygiene to ensure that all children learn at an early age how to protect themselves and others from preventable exposure to illness and other hazards related to poor hygiene. This can be carried out through formal (as a part of the curriculum) and informal health education messages.
Strategies to Educate Traditional Market Traders Based on Information Technology in Beringharjo Market, Yogyakarta City
Authors: Tiurmida Nelly , Triono Tomi Agus , Sulistiana Utami , Sugiyanto Sugiyanto 
Published: December 2022

The research strategy educates traditional market traders based on information technology using a qualitative approach to case studies. Data were collected through observation, interviews and documentation studies. The validity of the data is processed through tests of the degree of trust, transferability, dependence and certainty. Informance is determined by purposive sampling techniques, then the data is analyzed following qualitative rules. The research aims to explore how the Trade Office educates market traders in Pasar Beringharjo through a digitalization program. The results showed that the Department of Trade in educating market traders based on information technology uses strategies: a) external party cooperation, training, mentoring, developing insights and involving trader family members for traders who are constrained by brainware. The driving factors in educating information technology-based traders include: high participation of information technology companies, demands for government and merchant needs, government awareness of IT developments to preserve and develop the market, covid 19 outbreak, high merchant commitment supported by mobile phone communication tools. The inhibiting factors in educating information technology-based traders include the hardware and software owned by merchants, not all smartphones, as well as merchant culture that is still conventional. The results of the merchant market digitization program maintain commitment and are able to carry out online transaction systems with various application models such as Gopay or e-wallet, QRIS, E-Retribution, LinkAja, Grocery, InMobi, Titipku, and Semar by scanning barcodes and other eknik t.
Pesantren, Dinamika, dan Tantangan Global: Analisis UU Pesantren No.18 Tahun 2019
Authors: Diana Handayani  
Published: December 2022

The purpose of this article is to discuss 1) the background to the passing of the Undang-Undang Pesantren (UU Pesantren [Islamic Boarding School Law]) no. 18 of 2019; 2) the implementation analysis of the UU Pesantren, and 3) the positive impact of the stipulation of the UU Pesantran. The type of method or approach used in writing this article is library research. The findings of this article state that the positive impacts of passing the Islamic Boarding School Law are: 1) providing recognition, affirmation, and facilitation; 2) graduates are equivalent to other formal education; 3) maintaining independence, and 4) having a large enough space and role in the field religious. As for the negative impacts, namely: 1) pesantren that do not have an establishment permit are not recognized and can be disbanded; 2) offend the authority of the Kyai; 3) this 'new' regulation does not seem to take into account the diversity of pesantren in Indonesia, and 4) is not transparent or open regarding funding.
Keywords: Islamic Boarding School Law, Dynamics, and Global Challenges
Tujuan artikel ini ialah untuk membahas 1) latar belakang disahkannya Undang-undang Pesantren No 18 Tahun 2019; 2) analisis implementasi dari UU Pesantren, dan 3) dampak ditetapkannya UU Pesantren tersebut. Jenis metode atau pendekatan yang digunakan dalam tulisan artikel ini adalah studi kepustakaan. Hasil temuan artikel ini menyebutkan bahwa dampak positif disahkannya UU Pesantren, yaitu: 1) pemberian pengakuan (rekognisi), afirmasi dan fasilitasi 2) lulusan setara dengan pendidikan formal lainnya, 3) menjaga independensi, 4) memiliki ruang dan peran yang cukup besar dala bidang keagamaan. Adapun dampak negatifnya, yaitu: 1) pesantren yang tidak memiliki izin pendirian tidak diakui dan dapat dibubarkan, 2) menyinggung otoritas Sang Kyai, 3) peraturan 'baru' ini nampak seperti tidak memperhitungkan keberagaman pesantren di Indonesia 4) tidak transparan atau terbuka mengenai pendanaan.
STRATEGI GURU DALAM MENGEVALUASI PEMBELAJARAN BAHASA INGGRIS ANAK USIA DINI DI PAUD AL-MADANI
Authors: Toyyibah12 Baldatun , Mutamainnah Latifatul , Khoiriyah Wardatul , Jahrawi Nadila , Kamilah Bintan , Maszaeri  , Wardani Lyza 
Published: December 2022

Perkembangan zaman saat ini menuntut adanya keterampilan-keterampilan individual pada diri seseorang, salah satunya yakni keterampilan bahasa asing. Mengembangkan keterampilan dan bakat merupakan salah satu dari tujuan pendidikan, terlebih jika hal ini diterapkan pada jenjang usia dini. Oleh karena itu, diharapkan sekolah dan guru dapat memfasilitasi baik dalam sarana prasarana dan juga proses pembelajarannya, seperti strategi dalam menciptakan suasana belajar yang menyenangkan. Penelitian ini bertujuan untuk mendeskripsikan evaluasi pembelajaran bahasa Inggris. Penelitian ini menggunakan metode pendekatan deskriptif. Pengumpulan data menggunakan teknik observasi, wawancara, dokumentasi. Alat pengumpul data panduan wawancara, pedoman observasi, catatan lapangan, dokumen. Hasil penelitian menunjukkan: 1. Teknik evaluasi hasil belajar pembelajaran bahasa Inggris, 2. Strategi pembelajaran bahasa Inggris untuk anak usia dini, 3. Faktor pendukung pembelajaran bahasa Inggris adalah ketersediaan media pembelajaran bahasa Inggris yang telah disediakan oleh lembaga dan guru. 4. Faktor penghambat pembelajaran bahasa Ingris adalah karenakan bahasa Inggris bukan bahasa utama yang digunakan anak usia dini, 5. Guru mengamati proses pembelajaran dan menilai pekerjaan anak sebagai evaluasi.
TOURISM PROMOTION STRATEGY OF THE DINAS KEPEMUDAAN OLAHRAGA DAN PARIWISATA OF PONTIANAK CITY IN INCREASING TOURIST VISITS
Authors: Supiati  , Bob Andrian  , Evi Hafizah  
Published: December 2022

This research focuses on the development strategy of tourist visits to Pontianak City from 2016 to 2020. The research is aimed at finding out how the promotion strategy of the Tourism Sector increases tourist visits at the Pontianak City DISPORAPAR in 2019. This research uses descriptive qualitative methods with observation, interview, and documentation techniques. The results of the study that the Tourism Promotion Strategy in increasing tourist visits went through three stages. Planning is carried out through setting a promotional budget, determining the target market analysis, promotion goals, and message planning. Tahap implementation activities by carrying out promotional activities, using promotional media, and tourism events. While the evaluation stage is an evaluation meeting, a report on the performance of responsibility for one period.
Painful Fibrous Nonunion of a Posterior Oblique Ligament Bony Avulsion Fracture Associated With Anterior Cruciate Ligament Tear
Authors: Smith John-Rudolph H. , Dittman Lauren E. , Camp Christopher L. , Levy Bruce A. 
Published: December 2022

Case:
This report describes a case of a posterior oblique ligament (POL) bony avulsion fracture associated with an anterior cruciate ligament (ACL) tear in a 16-year-old female gymnast. The avulsion fracture was discovered on repeat radiographs and magnetic resonance imaging after the patient developed increased pain after ACL reconstruction. After excising the bony avulsion and repairing the POL, she reported complete resolution of her preoperative pain.

Conclusion:
Bony avulsion fractures of the POL are rare and challenging to diagnose. Awareness of this injury and the subtle imaging findings will help clinicians appropriately diagnose and treat these lesions.
Android-Based E-Module Development on Network Operating System Material
Authors: Imamah Nur , Hasanah Fitria Nur 
Published: December 2022

The purpose of this study was to produce an android-based e-module learning product on the material of the class XI TKJ network operating system and to determine the feasibility of an android-based e-module. This type of research uses R & D Research and Development with the ADDIE research and development model consisting of alaysis (analysis), design (design), development (development), implementation (Implementation) and evaluation (evaluation) stages. class XII TKJ SMK Muhammadiyah 1 Taman, the implementation is in class XI TKJ students. After the development process, media experts and material experts were validated as well as small-scale trials consisting of 5 students. So it can be concluded that android-based e-modules are suitable for use as teaching materials with the results of media expert validation of 86.6% in the very feasible category, the results of material expert validation by 85% in the very feasible category and small-scale trials getting an average percentage by 83.26%.
The Impact of Firm Size, Capital Structure and Dividend Policy on Firm Value during Covid-19 Pandemic
Authors: Purnamasari Dian Indri , Fauziah Muthia Riza 
Published: December 2022

The present study aims to obtain empirical evidence for the impact of firm size, capital structure and dividend policy on the firm value of hotel, restaurant, and tourism companies listed on the Indonesia Stock Exchange (IDX) for the years 2019-2020. The data used in this research are secondary data obtained from companies’ annual reports. The study population comprised of hotel, restaurant, and tourism companies listed on IDX for the years 2019-2020. The sample consists of 24 hotel, restaurant, and tourism companies listed on IDX for the years 2019-2020 and selected using a purposive sampling technique. The study used a multiple linear regression analysis. The results suggested that firm size, capital structure, and dividend policy have no impact on the firm value of hotel, restaurant, and tourism companies listed on IDX for the years 2019-2020.
Wnt activation-induced disturbance of cell competition causes diffuse invasion of transformed cells through upregulation of NF-κB-mediated MMP21
Authors: Nakai Kazuki , Lin Hancheng , Yamano Shotaro , Tanaka Shinya , Kitamoto Sho , Sakuma Kenta , Kurauchi Junpei , Akter Eilma , Konno Masamitsu , Koseki Jun , Takahashi Hirotaka , Yokoyama Hideshi , Shiraki Yukihiro , Enomoto Atsushi , Abe Sohei , Hayakawa Yoku , Ushiku Tetsuo , Mutoh Michihiro , Fujita Yasuyuki , Kon Shunsuke 
Published: December 2022

Abstract
Normal epithelial cells exert their competitive advantage over RasV12-transformed cells and eliminate them into the apical lumen via cell competition. However, the internal or external factors that compromise cell competition and provoke carcinogenesis remains unknown. In this study, we examined the effect of sequential accumulation of gene mutations, mimicking multi-sequential carcinogenesis on RasV12-induced cell competition in intestinal epithelial tissues. Consequently, we found that directionality of RasV12-cell extrusion in Wnt-activated epithelia is reversed, and transformed cells are delaminated into the basal lamina via non-cell autonomous MMP21 upregulation. Subsequently, diffusively infiltrating, transformed cells develop into highly invasive carcinomas. Elevated production of MMP21 is elicited partly through NF-κB signaling, blockage of which restores apical elimination of RasV12 cells. We further found that the NF-κB-MMP21 axis is significantly bolstered in early colorectal carcinoma in humans. Collectively, this study shows that cells with high mutational burdens exploit cell competition for their benefit by behaving as unfit cells, endowing them with an invasion advantage.
Kano Perspective Method: Analysis of Main Factors that Affects Patients’ Satisfaction in Attempt to Improve Dental Treatment Qualities in Government Hospitals
Authors: Akbar Fuad Husain , Mattoreang Ainun Habi 
Published: December 2022

Abstract
Background: Research on patient’s satisfaction is rarely conducted in hospitals. Most studies on satisfaction focused on variables such as service quality and satisfaction with medical services and their relationship, whilst only several of them explored variables regarding patient satisfaction. Assessment of the quality of dental care services is still relatively primitive. Thus, this study integrated the structure-process-outcome framework from Donabedian, and the two-dimensional quality model from Kano, to identify the main factors of patient satisfaction in attempt to improve dental care services.
Methods:This was an analytic observational study with a cross sectional design. Patients aged 12 to 65 years, who visited the dental clinic in designated research hospitals for dental treatment at the time of the study were recruited as subjects. Afterwards, an adapted Kano's perspective (Kano's method) questionnaire was given to respondents. The questionnaire consisted of a paired question, there were functional and dysfunctional questions.
Results: After conducting research at South Sulawesi’s government hospitals, 303 respondents, who visited the dental clinic at the research designated hospital, were then scouted for this study. From the patient's point of view, most of the service elements were classified as must-be attributes, namely 12 elements. In addition, 9 elements were classified as one-dimensional attributes (one size) and 7 elements were classified as attractive attributes; the rest were classified as indifferent (neutral) attributes.
Conclusion: Overall, the patients were positively satisfied with all elements of the service carried out by the dental care sector of the hospital studied. However, there were some elements of service that need to improve because due to their low level of assessment.
The influence of antihypertensive drugs on hemodynamic parameters of cerebral arteries assessed by transcranial Doppler
Authors: Machado Michel , Muela Henrique Cotchi Simbo , Costa-Hong Valeria Aparecida , Panerai Ronney B. , Moraes Natalia C. , Memoria Claudia M. , Bor-Seng-Shu Edson , Nitrini Ricardo , Bortolotto Luiz Aparecido , Nogueira Ricardo de C. 
Published: December 2022

Abstract
Arterial hypertrophy and remodeling are adaptive responses present in the systemic arterial hypertension (SAH). As a result, antihypertensive drugs (AHD) begin to play an important role in controlling the cerebral blood flow. To evaluate the influence of AHD on cerebral hemodynamic parameters (CHP). Three groups of patients were compared: hypertensive with systolic blood pressure (SBP) < 140 and diastolic blood pressure (DBP) < 90 mmHg (n = 54), hypertensive with SBP > 140 or DBP > 90 mmHg (n = 31) and normotensive (n = 30). Simultaneous measurements of systemic blood pressure (BP) and middle cerebral artery (MCA) blood flow velocity (CBFV) were obtained from digital plethysmography and Transcranial Doppler. The use of diuretics (p = 0.047) and α-agonists (p = 0.009) reduced the pulsatility index (PI) among uncontrolled hypertensives, but did not change their arterial stiffness in relation to the others groups (RAP 1.7 [± 0.7], p < 0.001). There was no correlation between ADH and other CHP, although the RAP of controlled hypertensives was comparable to that of normotensives. Among uncontrolled hypertensives, the use of AHD with direct vasodilating action actively reduces PI, so it does not reflect a real cerebrovascular resistance of adaptive histological changes. This effect seems to be smaller among controlled hypertensives, due to their lower arterial stiffness, probably resulting from the attenuation of these changes.