bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quality of life and surgical outcomes in incidental pituitary adenomas undergoing endoscopic endonasal resection
Authors: Castle-Kirszbaum Mendel , Wang Yi Yuen , King James , Kam Jeremy , Goldschlager Tony 
Published: July 2022

OBJECTIVE
Incidental, asymptomatic pituitary adenomas require nuanced, shared decision-making, which is limited by a poor understanding of their natural history and effects on quality of life (QOL). A greater understanding of the effects of surgery would inform evidence-based care.

METHODS
A multicenter review of consecutive pituitary adenomas resected via an endoscopic endonasal approach (EEA) between late 2016 and mid-2021 was performed, with prospective, longitudinal QOL assessment (at 3 and 6 weeks and at 3, 6, and 12 months) postoperatively using the 35-item Anterior Skull Base Questionnaire.

RESULTS
Of 366 adenomas resected during the study period, 52 (14.2%) were incidentally discovered, of which 51 (98.1%) were macroadenomas. Preoperative QOL in patients with these incidentalomas was better than in those with adenomas presenting with endocrinopathy (p < 0.01), visual failure (p = 0.02), or headache (p = 0.03). Surgery was performed due to visual field deficits (13.5%, n = 7); ophthalmoplegia (1.9%, n = 1); radiological compression or contact of the optic apparatus (63.5%, n = 33); functional status (growth hormone–secreting tumor) (5.8%, n = 3); and clinically significant growth (15.4%, n = 8). Surgical outcomes were excellent, with vision improved in 100% (7/7) and complete resection in 84.6% (44/52). There were 2 (3.8%) cases of new cortisol deficiency, 3 (5.8%) cases of transient postoperative diabetes insipidus, and 4 (7.7%) cases of postoperative hyponatremia. There were no perioperative complications and no cases of postoperative CSF leakage. QOL transiently decreased during the first 3 weeks after surgery, then improved to above baseline levels by 3 months (p = 0.03) and continued to improve throughout the first postoperative year (p = 0.03). All surgical indications demonstrated an overall mean improvement in QOL at 3 months. QOL benefits were not affected by age or tumor size.

CONCLUSIONS
Resection of pituitary adenomas via the EEA provided a tangible benefit for patients within 3 months. Surgery via the EEA is safe, effective, and beneficial for patients with pituitary incidentalomas meeting accepted criteria for intervention.
Precision medicine in pediatric temporal epilepsy surgery: optimization of outcomes through functional MRI memory tasks and tailored surgeries
Authors: Goldstein Hannah E. , Poliakov Andrew , Shaw Dennis W. , Barry Dwight , Tran Kieu , Novotny Edward J. , Saneto Russell P. , Marashly Ahmad , Warner Molly H. , Wright Jason N. , Hauptman Jason S. , Ojemann Jeffrey G. , Shurtleff Hillary A. 
Published: July 2022

OBJECTIVE
The goal of epilepsy surgery is both seizure cessation and maximal preservation of function. In temporal lobe (TL) cases, the lack of functional MRI (fMRI) tasks that effectively activate mesial temporal structures hampers preoperative memory risk assessment, especially in children. This study evaluated pediatric TL surgery outcome optimization associated with tailored resection informed by an fMRI memory task.

METHODS
The authors identified focal onset TL epilepsy patients with 1) TL resections; 2) viable fMRI memory scans; and 3) pre- and postoperative neuropsychological (NP) evaluations. They retrospectively evaluated preoperative fMRI memory scans, available Wada tests, pre- and postoperative NP scores, postoperative MRI scans, and postoperative Engel class outcomes. To assess fMRI memory task outcome prediction, the authors 1) overlaid preoperative fMRI activation onto postoperative structural images; 2) classified patients as having "overlap" or "no overlap" of activation and resection cavities; and 3) compared these findings with memory improvement, stability, or decline, based on Reliable Change Index calculations.

RESULTS
Twenty patients met the inclusion criteria. At a median of 2.1 postoperative years, 16 patients had Engel class IA outcomes and 1 each had Engel class IB, ID, IIA, and IID outcomes. Functional MRI activation was linked to NP memory outcome in 19 of 20 cases (95%). Otherwise, heterogeneity characterized the cohort.

CONCLUSIONS
Functional MRI memory task activation effectively predicted individual NP outcomes in the context of tailored TL resections. Patients had excellent seizure and overall good NP outcomes. This small study adds to extant literature indicating that pediatric TL epilepsy does not represent a single clinical syndrome. Findings support individualized surgical intervention using fMRI memory activation to help guide this precision medicine approach.
The usefulness and safety of dexmedetomidine for postoperative sedation in pediatric patients with moyamoya disease
Authors: Kanamori Fumiaki , Araki Yoshio , Yokoyama Kinya , Uda Kenji , Kurimoto Michihiro , Shiba Yoshiki , Mamiya Takashi , Takayanagi Kai , Ishii Kazuki , Nishihori Masahiro , Izumi Takashi , Okamoto Sho , Saito Ryuta 
Published: July 2022

OBJECTIVE
After revascularization surgery in pediatric patients with moyamoya disease (MMD), resting and avoiding crying is important. However, this inaction is often difficult because of pain or anxiety. Dexmedetomidine (DEX), which has sedative and analgesic properties, may be useful in reducing those uncomfortable conditions; however, its common side effects include bradycardia and hypotension, which have a risk of decreasing the cerebral blood flow. The aim of this study was to investigate the efficacy and safety of using DEX for pediatric patients with MMD in the acute period after revascularization surgery.

METHODS
This retrospective study included pediatric patients with MMD who underwent revascularization surgery. Based on whether DEX was used for light sedation during postoperative days (PODs) 0–1 after extubation, the patients were divided into DEX or control groups. For neurological outcomes, the incidence of symptomatic cerebral infarction and transient neurological events (TNEs) during PODs 0–1 and the entire hospitalization were investigated. In addition, the Richmond Agitation-Sedation Scale (RASS) was used to assess the effect of DEX, and bradycardia and hypotension were evaluated as side effects.

RESULTS
A total of 84 surgical procedures were included in this study (27 in the DEX group and 57 in the control group). During PODs 0–1, symptomatic infarction was not observed in either group. The incidence of TNEs was almost the same in both groups: 2 (7.4%) of the 27 procedures in the DEX group and 4 (7.0%) of the 57 procedures in the control group (p > 0.99). Moreover, the incidences of symptomatic infarction and TNEs during the entire hospitalization did not differ significantly (symptomatic infarction, p > 0.99; TNEs, p = 0.20). Regarding the DEX effect, the median RASS scores during PODs 0–1 were −1.0 (drowsy) in the DEX group and +1.0 (restless) in the control group, showing a significant difference (p < 0.01). Regarding side effects, bradycardia was observed only in 3 (11.1%) of the 27 procedures in the DEX group (p = 0.03), and hypotension was not observed in any of the cases.

CONCLUSIONS
In pediatric patients with MMD who are extubated after revascularization surgery, DEX produced appropriate light sedation and analgesia. The risk for symptomatic infarction is almost the same in cases in which DEX is used and those in which it is not; however, neurosurgeons should be cautious of bradycardia and TNEs as potential side effects.
Upaya Pengembangan Umkm Digital Keripik Tempe Pa-da Industri Kecil Di Desa Balet Baru Kecamatan Su-kowono
Authors: Kerta Wekel Mega wisesa , Dania Liara Ayu Rahma , Fibrianti Trisya Bella , Ishaq Rifyal Zaihifni , Rini Ristanti Nurin Aqua , Abdillah Fahmi Malik 
Published: July 2022

Usaha Mikro Kecil Menengah (UMKM) memiliki peran yang besar pada perekonomian negara, baik dalam kontribusi terhadap Produksi Domestik Bruto maupun jumlah penyerapan tenaga kerja. Dalam usaha mengembangkan bisnisnya, UMKM keripik tempe Daffa harus melakukan inovasi dan perbaikan untuk dapat bersaing dengan bisnis lainnya. Pengabdian ini bertujuan untuk mengembangkan produksi dan pengemasan kripik tempe serta mengenalkan produksi kepada masyarakat secara luas. Pengabdian ini dilakukan di wilayah Desa Balet Baru sebagai tempat pengabdian mahasiswa KKN kelompok 107 Desa Balet Baru Universitas Muhammadiyah Jember. Metode yang digunakan berupa penyuluhan kepada pemilik usaha keripik tempe tentang cara pemasaran secara online dan offline serta cara mendesain kemasan yang menarik. Proses produksi keripik tempe yang pertama yaitu pembuatan bahan-bahan, yang kedua yaitu penggorengan dan pengemasan, yang ketiga yaitu pemasaran. Harapan dari pemilik tempat usaha dan mahasiswa KKN yaitu daya jangkau pemasaran secara online atau offline semakin luas, sehingga pendapatan UMKM akan bertambah dan dapat meningkatkan tarif hidup keluarga.
Ultrasonic Scattering in Two-Phase Polycrystalline Materials
Authors:   University of Nebraska-Lincoln, Islam Showmic , Tunrer Joseph A. 
Published: July 2022

Many of the polycrystalline materials found in nature and those created using different manufacturing processes consist of multiple phases. Careful nondestructive characterization of these materials is of fundamental importance for quality assurance because microstructure is strongly correlated with mechanical performance. Ultrasonic scattering measurements have shown high sensitivity to material microstructure such that this approach is of interest for multi-phase materials. A fundamental understanding of scattering from idealized two-phase materials would provide essential information regarding the predictive nature of scattering measurements to quantify such microstructures. For this purpose, samples were created using spark plasma sintering (SPS) from mixtures with three different ratios (with respect to mass) of Cu and Fe powders. The three samples are •	Cu-25 sample (mixture of 25% Cu & 75% Fe powder based on mass) •	Cu-50 sample (mixture of 50% Cu & 50% Fe powder based on mass) •	Cu-75 sample (mixture of 75% Cu & 25% Fe powder based on mass).
Закономірності зміни оптимальних складу і параметрів силових установок з прямоточними контурами від швидкості надзвукового крейсерського польоту
Authors: Kislov Oleh , Shevchenko Mykhailo 
Published: July 2022

There are two aircraft concepts for transoceanic flights at supersonic speed. The first is the aircraft with moderate supersonic cruising speed M = 1.7...2.2, and the second is the aircraft with cruising speed M ≥ 3. Propulsion with a ramjet engine (ramjet) is preferable for high supersonic speeds. However, a ramjet has no starting thrust and is uneconomical at subsonic flight speeds. Combined propulsion with a turbojet duct for takeoff and a ramjet duct for supersonic cruise flight are used to overcome this contradiction. There are known propulsion with turboramjet engines, as well as various propulsion schemes with turbofan engines (afterburning and duct-burning ones), in which the outer contour together with the afterburner and nozzle can be considered the ramjet duct. When the turbojet duct is turned off, the operating process of such turbofan engines is practically the same as the ramjet, which allows using the advantages of a ramjet in supersonic cruise flight. Because flight at supersonic cruising speed can be provided by different propulsion compositions, the choosing problem of the composition and parameters of the propulsion for an aircraft with supersonic cruising speed is relevant. A calculation-analytical method was used to select the composition and parameters of the propulsion, which is based on the maximum relative mass of the payload criterion. Using the aircraft mass balance equation this criterion can be represented as a minimum conditions for the relative mass of the fuel and propulsion. Using this method, for an aircraft with a given mass, aerodynamic characteristics and a given flight profile, for the indicated propulsion compositions, the change patterns of the minimum relative mass of fuel and propulsion in the range of M = 2.5...4 are established. The established patterns allow choosing the propulsion composition and parameters depending on the speed of the supersonic cruising flight or choosing the flight speed of the aircraft at a given propulsion composition. The dependance of the propulsion working process optimal parameters for takeoff and cruising mode on the speed of supersonic cruising flight according to the criterion minimum of relative mass of fuel and propulsion were obtained.
EFEKTIVITAS PELAKSANAAN FUNGSI PENGAWASAN DI INSPEKTORAT DAERAH KABUPATEN KERINCI
Authors: Putra Livia Simon , Susanti Susi 
Published: July 2022

Purpose: Rulers or leaders need to carry out supervision, because without supervision will result in deviations. The implementation of supervision, both seen from inspection, testing to investigation, has not been running effectively, this is due to the lack of timeliness in conducting supervision, the inaccurate data on deviations found for the supervisory apparatus at the District Inspectorate office. Kerinci. Basically, supervision is not intended to find fault and impose sanctions or penalties, but supervision is intended to find out the real reality regarding the implementation of organizational activities.
Design/Methodology/Approach: This research was conducted with a qualitative approach. Data obtained directly from the object of research with data collection techniques, namely the interview method.
Findings: The implementation of supervision has not been effective, this is due to the inaccuracy of time in conducting supervision, the inaccuracy of the deviation data found for the supervisory apparatus. Factors influencing the implementation of the Inspectorate's supervision in Kerinci Regency include officers who do not yet have good skills, the data used are not objective and unrealistic, and the lack of knowledge in the field of work being handled, even though the available facilities and infrastructure have supported the implementation of supervision.
Research implications: Based on the research results that have been achieved, it is known that the implementation of supervision has not been fully effective, therefore the findings from this research become an input for the Kerinci Regency Inspectorate to improve the ability of employees in order to optimize reporting time.
Reflections on Co-production, Lived Experience and the Shared Learning Environment within the Development and Early Delivery of a Recovery College.
Authors: Ali Imran , Benkwitz Adam , McDonald Paul , Allen Katherine , Glover Anne 
Published: July 2022

Objective: This study sought to explore and value the experiences of the service users, staff, carers and volunteers who were involved in the development and early establishment of a recovery college in a large mental health Trust in the United Kingdom.
Research Design and Methods: This qualitative study used Interpretative Phenomenological Analysis (IPA) to explore the experiences of 25 participants who were involved in the design, development and early delivery phases of the recovery college. Data was collected using face-to-face semi-structured interviews.
Results: The findings discuss a number of key features relating to participants’ experiences of the development of the recovery college, with the central themes being: 1) co-production; 2) lived experience; and 3) the shared learning environment.
Conclusions: Key recommendations for those seeking to develop their own recovery college include: i) co-production is essential, but there are both philosophical and practical considerations; ii) lived experience is valuable, but it needs to be valued and supported within both the recovery college and the host organisation; and iii) the shared learning environment and educational approach of the college is vital and needs equity of opportunity between the service users, staff, carers and volunteers involved.
Risco e perigo
Authors: Rezende Maria José de 
Published: July 2022

Risco e perigo são noções que estão presentes em diversas áreas da ciência. Na Sociologia não poderia ser diferente. Há nas suas formulações uma vasta discussão sobre esses dois conceitos que têm sido empregados para retratar as várias situações de suposta, real ou potencial ameaças à vida individual e coletiva. Ao longo da história há momentos em que o risco e o perigo ganham dimensões desafiadoras tanto para as Ciências Sociais e Humanas quanto para as Ciências Naturais. A partir de 2019, isso se torna evidenciado com o surto pandêmico da COVID 19. Este estudo tem como material empírico os diagnósticos e as prescrições expostos nos documentos preparados pelas Nações Unidas para propor - aos governantes, aos Estados, às lideranças políticas e organizações da sociedade civil - ações, práticas e procedimentos tanto para proteção dos mais vulneráveis, no contexto pandêmico, quanto para definir medidas de combate aos impactos sociais e econômicos decorrentes do Sars-Cov-2. Constatou-se que os documentos produzidos dentro do sistema ONU enfatizam sobremaneira, em suas proposições prescritivas, os riscos sociais, econômicos e políticos derivados da pandemia, ou seja, os riscos vão muito além do perigo de contágio que já é, por demais, preocupante.
Palavras-chave: Risco e perigo. Pandemia Covid-19. Nações Unidas. Proposições prescritivas.
A ocorrência do Zika vírus durante a pandemia da Covid-19 em Uberlândia, Minas Gerais, Brasil
Authors: Rodrigues Elisangela , Martins Costa Iram 
Published: July 2022

A ocorrência do Zika vírus no município de Uberlândia (MG) foi registrada inicialmente em 2016, quando os primeiros casos da doença foram notificados. O presente trabalho foi desenvolvido com o objetivo de estudar a situação epidemiológica do Zika Vírus, em meio à pandemia da Covid-19, dando a conhecer a distribuição espacial, sazonal, por faixa etária e sexo dos pacientes, no período da pandemia, nos anos de 2019-2021, no município de Uberlândia. A metodologia utilizada trata-se de um estudo ecológico, descritivo. A pesquisa foi feita por meio do levantamento de casos da doença no banco de dados da Vigilância Epidemiológica da Secretaria Municipal de Saúde (SMS) de Uberlândia. No período de 2019 a 2021 foram confirmados 191 casos. Durante a pandemia de Covid-19, houve queda nos casos de Zika em relação ao ano de 2019: 87,3% em 2020 e 97% em 2021. A maior incidência da doença foi nos bairros do Setor Sul (28,3%), seguido pelo Setor Norte (22,5%). A sazonalidade dos casos ocorreu predominantemente no primeiro semestre de cada ano de estudo, verificou-se a redução da taxa de incidência de casos nos meses subsequentes, com a chegada do inverno. Considerando o perfil epidemiológico cerca de 78% da população afetada foi do sexo feminino. A faixa etária predominante foi na fase adulta (21 a 59 anos) com 78,5%. A análise da situação epidemiológica da Zika em Uberlândia revelou um grave problema de saúde pública como em grande parte dos municípios do país.
PALAVRAS-CHAVE: Covid-19; Pandemia; Uberlândia; Vírus; Zika.
Modelo de integración de formación profesional de la carrera de licenciatura en enfermería en la UTEQ.
Authors: Velázquez Lores Lourdes María , García Parrales Silvia Leonor , Pazmiño Solys. Gabriel Arturo , Mego Cubas Carlos 
Published: July 2022

El rediseño curricular es fundamental, es por esto que se trató este tema, en este caso de una institución de servicio educativo como es la UNIVERSIDAD ESTATAL DE QUEVEDO, entre las 5 más importantes del país. La idea de esta propuesta es el rediseño de la malla curricular de la Carrera de Licenciatura Enfermería con la inserción de las asignaturas que ayudaran al estudiante una vez concluido sus estudios afrontar con conocimientos prácticos y teórico el inicio de su vida profesional demostrando lo aprendido durante su tiempo de estudiante . La metodología de esta investigación es del modelo cualitativo cuantitativo (mixto) y descriptivo, logrando la elaboración de una propuesta factible con elementos técnicos como son el cálculo de la muestra poblacional participante recopilando información para luego ser procesada. Con los resultados estadísticos se pude graficar y analizar la información obtenida de los involucrados en este estudio que componen la carrera de Licenciatura Enfermería de la Universidad Estatal de Quevedo, e intervienen en el proceso de calidad total de la educación superior.
PENENTUAN MINAT KONSUMEN TERHADAP PRODUK MENGGUNAKAN ALGORITMA APRIORI PADA PT.TELKOM INDONESIA
Authors: Longgana Pardo Frans , Irvan Irvan , Wilarto Anjar Hero 
Published: July 2022

Dengan adanya kegiatan pesanan penjualan setiap hari, data semakin lama akan semakin bertambah. Data tersebut seharusnya dapat dimanfaatkan dan diolah menjadi informasi untuk meningkatan pesanan penjualan. Permasalahan yang timbul di PT. Telkom Indonesia Divisi Business Service (DBS) yaitu sering sekali pihak sales tidak mengetahui produk apa saja yang banyak di minati oleh konsumen sehingga produk yang lain tidak diminati dengan cepat. Tujuan dari penelitian ini adalah untuk mendapatkan informasi minat konsumen dari produk-produk di PT. Telkomunikasi Indonesia Segement Hospitality Bussiness Service (HBS) dan mengetahui strategi dalam penjualan berdasarkan pola dan rule algoritma apriori. Dalam penelitian ini, Association Rule berfungsi untuk menganalisa seberapa sering suatu produk yang sering dijual secara bersamaan, analisis ini akan ditinjau dari data pesanan yang telah terjadi. Penerapan Algoritma Apriori dalam aplikasi ini berhasil mencari kombinasi item terbanyak berdasarkan data pesanan dan kemudian membentuk pola asosiasi dari kombinasi item tersebut. Hasil penelitian ini secara keseluruhan didapatkan rata-rata nilai pengujian user acceptance testing dengan metode TAM (Technology Acceptance Model) sebesar 89,6% dan secara keseluruhan model Data Mining dengan menggunakan metode apriori dapat diterima dengan sangat baik oleh user.
Osteoporose densitometrica: perfil epidemiológico de um município do sudoeste goiano
Authors: Soares Fernando Augusto Maciel , Wenning Gisele Dal , Costa Sara de Queiroz , Prado Neto Severino Correia do 
Published: July 2022

Objetivos: Avaliar a prevalência de osteoporose em pacientes idosos de Mineiros-GO e comparar os dados encontrados com dados da população mundial, identificando diferenças ou semelhanças. Metodologia: Estudo retrospectivo, descritivo e transversal. Os dados foram coletados através do acesso aos exames de densitometria óssea (DMO) realizados entre 2017-2021 no Centro Diagnóstico de Imagem em Mineiros-GO, em pacientes com idade ≥ 60 anos. Foi utilizado a versão 26,0 para analisar os resultados (Statistical Package for Social Science). Resultados: Dos 315 pacientes, 97,1% eram mulheres. A média da faixa etária foi de 71 anos. Dentre os sítios pesquisados o antebraço foi realizado em menor frequência. Pacientes com idade avançada apresentaram menores valores de massa óssea. Correlacionando valor de massa óssea e sexo houve diferença apenas em rádio 33%, onde mulheres apresentam valores inferiores. Valores de T-escore compatíveis com osteoporose, foram mais prevalentes em pacientes com idade ≥70 anos. Essa análise em relação ao sexo, não apresentou diferença significativa. Enfim, foi observado que nenhum indivíduo do sexo masculino realizou DMO de controle. Em contrapartida, a maioria das mulheres que repetiram o exame fizeram em 2 anos ou menos após a realização do primeiro exame. Conclusão: A osteoporose é uma doença prevalente em nosso meio. Portanto, é necessária atenção dos profissionais de saúde, principalmente grupos de risco, como idade ≥70 anos. Ademais, diferenças relacionadas ao sexo precisam ser valorizadas, como a baixa taxa de realização de DMO em homens e menores valores de massa óssea em rádio em mulheres.