bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characteristics of Female Sexual Health Programs and Providers in the United States
Authors: Stanley Elizabeth E. , Pope Rachel J. 
Published: May 2022

Abstract

Background
Female sexual dysfunction is a prevalent condition affecting 12% of women, yet few academic centers in the US have female sexual medicine programs.

Aim
To characterize female sexual health programs in the United States, services offered, and training of female sexual health providers.

Methods
We performed an internet search to identify female sexual health programs and clinics in the US. From each programs’ website we abstracted the location, clinic setting (academic vs private), training of providers, and whether the clinic provided investigational services (ie, PRP injections, laser/radiofrequency therapy). We categorized clinics as specialized in sexual medicine, specialized with a focus on cancer patients, general, aesthetics-focused, general & aesthetic, or specialized & aesthetic. We used Chi-square and Fisher's exact test to evaluate association between practice setting and provision of investigational therapies with a Bonferroni-adjusted critical P-value of 0.017.

Outcomes
Our outcomes were the number of clinics in each setting, in each category, and each state, as well as the number of providers by training type.

Results
We identified 235 female sexual medicine programs in the United States. Seventeen percent were in the academic setting. Clinics in the non-academic setting were significantly (α = 0.017) more likely to offer PRP injections (0% vs 47%, P &lt; .001), laser/radiofrequency therapy (14% vs 56%, P &lt; .0001), and shockwave therapy (0% vs 14%, P = .011). Among all clinics, 22% provided specialized care, 2% provided care for cancer patients, 29% were more general clinics that advertised female sexual healthcare, 23% were aesthetics-focused, 22% were general practices that provided aesthetics services, and 2% were specialized clinics that offered aesthetics services. 81% of aesthetics-focused clinics advertised PRP injections. Seven states had no clinics and 26 states lacked a clinic specializing in female sexual health. The most frequent providers were OB/Gyns (40%), nurse practitioners (22%), urologists (13%), and physicians assistants (10%).

Clinical Implications
The geographic distribution of clinics and pervasiveness of clinics offering investigational services for female sexual dysfunction may be a barrier for patients seeking care.

Limitations
As a result of our internet search methodology, we likely did not capture all clinics providing female sexual health services. Further, the accuracy of our data depends on the level of detail provided on each clinics’ website.

Conclusion
Online search identified few clinics providing female sexual healthcare in academic medicine: development of such clinics could benefit patients by improving access to evidence-based care and promoting training of future providers.
Souvenirs and the Experience of Empire in Ancient Rome
Authors: Popkin Maggie 
Published: May 2022

In this book, Maggie Popkin offers an in-depth investigation of souvenirs, a type of ancient Roman object that has been understudied and that is unfamiliar to many people. Souvenirs commemorated places, people, and spectacles in the Roman Empire. Straddling the spheres of religion, spectacle, leisure, and politics, they serve as a unique resource for exploring the experiences, interests, imaginations, and aspirations of a broad range of people - beyond elite, metropolitan men - who lived in the Roman world. Popkin shows how souvenirs generated and shaped memory and knowledge, as well as constructed imagined cultural affinities across the empire's heterogeneous population. At the same time, souvenirs strengthened local identities, but excluded certain groups from the social participation that souvenirs made available to so many others. Featuring a full illustration program of 137 color and black and white images, Popkin's book demonstrates the critical role that souvenirs played in shaping how Romans perceived and conceptualized their world, and their relationships to the empire that shaped it.
TREE-BASED MACHINE LEARNING METHODS FOR MODELING AND FORECASTING MORTALITY
Authors: Bjerre Dorethe Skovgaard 
Published: May 2022

AbstractMachine learning has recently entered the mortality literature in order to improve the forecasts of stochastic mortality models. This paper proposes to use two pure, tree-based machine learning models: random forests and gradient boosting, based on the differenced log-mortality rates to produce more accurate mortality forecasts. These forecasts are compared with forecasts from traditional, stochastic mortality models and with forecasts from random forests and gradient boosting variants of the stochastic models. The comparisons are based on the Model Confidence Set procedure. The results show that the pure, tree-based models significantly outperform all other models in the majority of cases considered. To address the lack of interpretability issue associated with machine learning models, we demonstrate how to extract information about the relationships uncovered by the tree-based models. For this purpose, we consider variable importance, partial dependence plots, and variable split conditions. Results from the in-sample fit suggest that tree-based models can be very useful tools for detecting patterns within and between variables that are not commonly identifiable with traditional methods.
Impact of an inpatient nurse-initiated penicillin allergy delabeling questionnaire
Authors: Bediako Hilary , Dutcher Lauren , Rao Aditi , Sigafus Kristen , Harker Christina , Hamilton Keith W. , Fadugba Olajumoke 
Published: May 2022

Abstract
Penicillin allergy delabeling is an important component of antimicrobial stewardship and improves patient outcomes. We demonstrated the successful use of a nurse-initiated questionnaire to remove inappropriate penicillin allergy labels in inpatients. Nurses can play a key role in improving antibiotic allergy assessment and more broadly in interprofessional antimicrobial stewardship.
Invariant Ideal Axiom
Authors: Hrušák Michael , Shibakov Alexander 
Published: May 2022

AbstractWe introduce and prove the consistency of a new set theoretic axiom we call theInvariant Ideal Axiom. The axiom enables us to provide (consistently) a full topological classification of countable sequential groups, as well as fully characterize the behavior of their finite products.We also construct examples that demonstrate the optimality of the conditions inIIAand list a number of open questions.
Characteristics of nursing home residents and healthcare personnel with repeated severe acute respiratory coronavirus virus 2 (SARS-CoV-2) tests positive ≥90 days after initial infection: Four US jurisdictions, July 2020–March 2021
Authors: Wilson W. Wyatt , Hatfield Kelly M. , Tressler Stacy , Bicking Kinsey Cara , Parra Gemma , Zell Renée , Denson Anitra , Williams Channyn , Spicer Kevin B. , Kamal-Ahmed Ishrat , Abdalhamid Baha , Gemechu Mahlet , Folster Jennifer , Thornburg Natalie J. , Tamin Azaibi , Harcourt Jennifer L. , Queen Krista , Tong Suxiang , Jernigan John A. , Crist Matthew , Perkins Kiran M. , Reddy Sujan C. ,   for the Repeat Positive SARS-CoV-2 Test After 90 Days (REPOST-90) Study Team
Published: May 2022

AbstractOne in six nursing home residents and staff with positive SARS-CoV-2 tests ≥90 days after initial infection had specimen cycle thresholds (Ct) <30. Individuals with specimen Ct<30 were more likely to report symptoms but were not different from individuals with high Ct value specimens by other clinical and testing data.
Phenomenology of Gesture Between Heidegger and Flusser
Authors: Ciocan Cristian 
Published: May 2022

AbstractIn this article, I discuss two approaches to the phenomenon of gesture, constituted by the existential dimension of embodiment, intersubjectivity, affectivity, and language: while Martin Heidegger states that human bodily movement as a whole should be understood as gesture in contrast to the spatial movement of things, Vilém Flusser integrates under this notion a multitude of human practices and activities that common sense hesitates to call gestures. The dilemma of the phenomenology of gesture consists in this tension between the plural concreteness of gestural appearances and the irrepressible temptation to identify a unitary layer that would allow them to hold together.
A role for verb regularity in the L2 processing of the Spanish subjunctive mood: Evidence from eye-tracking
Authors: Fernández Cuenca Sara , Jegerski Jill 
Published: May 2022

AbstractThe present study investigated the second language processing of grammatical mood in Spanish. Eye-movement data from a group of advanced proficiency second language users revealed nativelike processing with irregular verb stimuli but not with regular verb stimuli. A comparison group of native speakers showed the expected effect with both types of stimuli, but these were slightly more robust with irregular verbs than with regular verbs. We propose that the role of verb form regularity was due to the greater visual salience of Spanish subjunctive forms with irregular verbs versus regular verbs and possibly also due to less efficient processing of rule-based regular inflectional morphology versus whole irregular word forms. In any case, the results suggest that what appeared to be difficulty with sentence processing could be traced back to word-level processes, which appeared to be the primary area of difficulty. This outcome seems to go against theories that suggest that L2 sentence processing is shallow.
Aging in Place in Social Housing: A Scoping Review of Social Housing for Older Adults
Authors: Sheppard Christine L. , Kwon Carol , Yau Matthew , Rios Jorge , Austen Andrea , Hitzig Sander L. 
Published: May 2022

AbstractAccess to affordable housing is a rising concern, and social housing is one approach to support low-income, older renters. A scoping review was undertaken to understand the characteristics of older tenants and social housing services to identify strategies to promote aging in place. Seven peer review databases were searched to identify relevant articles. A total of 146 articles were included. Almost all examined socio-demographic and health characteristics of older tenants, while 72 per cent examined social housing services, including eligibility policies, staffing, and access to on-site services. This review points to a high vulnerability among older tenants and highlights the importance of co-locating services on-site with a tenant-facing support staff to identify vulnerable tenants and link them to services. More research on tenancy issues (e.g., unit condition, rental management) is needed to identify new opportunities for social housing landlords to help older tenants age in place.
Anatomically corrected malposition of the great arteries (S,L,D) with mutation of Nodal gene
Authors: Putotto Carolina , Caruso Elio , Marino Bruno , Digilio Maria Cristina , Novelli Antonio , Agati Salvatore 
Published: May 2022

AbstractAnatomically corrected malposition of the great arteries is a rare CHD, involving alignment and position of the great arteries. We report an infant with situs solitus, atrioventricular discordance, and ventriculoarterial concordance with the aorta arising anteriorly and to the right of the pulmonary artery. A mutation of Nodal gene, implicated in the pathogenesis of human left–right patterning defects, was found.
Attentional problems occur across multiple psychiatric disorders and are not specific for ADHD
Authors: Grant Jon E. , Chamberlain Samuel R. 
Published: May 2022

AbstractObjectiveAttentional problems are common and have been associated with multiple psychiatric disorders. This study examined problems of sustained attention across a range of psychiatric disorders using a validated computerized trans-diagnostic attentional paradigm (a continuous performance task). We hypothesized that multiple psychiatric disorders, particularly attention deficit hyperactivity disorder (ADHD), would be associated with pronounced attentional problems.MethodsTotally, 576 non-treatment seeking participants (aged 18–29 years) were enrolled from general community settings, provided demographic variables, and underwent clinical assessments to detect mental health disorders. Each participant underwent the rapid visual information processing task, a validated computerized test measuring sustained attention. The two measures of sustained attention were the sensitivity index and target detection (proportion of targets detected). The profile of attentional deficits was examined across different disorders using z-scores relative to controls.ResultsParticipants with social phobia, obsessive-compulsive disorder (OCD), bulimia nervosa, and intermittent explosive disorder showed the greater impairment in target sensitivity, all with effect sizes of at least 0.8. Target detection was impaired across multiple disorders, with OCD and binge eating disorder exhibiting the most pronounced impairment. Post-traumatic stress disorder (PTSD) and compulsive sexual behavior were associated with particularly spared performance on both measures.DiscussionThese data indicate that impaired attention is non-specific for ADHD and in fact several other disorders are associated with markedly larger deficits. Instead of clinicians assuming sustained attention problems are due to ADHD, a variety of disorders should be screened for when people report attentional problems. Future work should examine the contribution of comorbidities and psychoactive substances (prescribed or illicit) to the profiles identified.
Age-Related Changes in Calcitonin-Producing Thyroid C-Cells of Male Wistar Rats
Authors: Filipović Branko , Ajdžanović Vladimir , Živanović Jasmina , Trifunović Svetlana , Ristić Nataša , Milošević Verica , Šošić-Jurjević Branka 
Published: May 2022

Abstract
Thyroid C-cells secrete the hormone calcitonin (CT) which acts as an inhibitor of bone resorption. Our aim was to examine the age-related changes in the structure and function of CT-producing C-cells, using histomorphometric, ultrastructural, and biochemical analyses. We used young adult (3-months-old), middle-aged (16-months-old), and old (24-months-old) male rats. The peroxidase-antiperoxidase method was applied for localization of CT. Stereological analysis was performed using the newCAST stereological software package. Serum samples were analyzed for the determination of CT, testosterone (T), calcium (Ca2+), and phosphorus (P). We found a significant increase in the volume density (Vv) of C-cells in both older groups (p &lt; 0.05). The percentage of smaller volume range C-cells increased (p &lt; 0.0001), while the proportion of greater volume range C-cells decreased (p &lt; 0.05) with ageing. Ultrastructural analysis revealed a larger number of secretory granules in older rats. Serum CT increased (p &lt; 0.001), while serum T and P were reduced (p &lt; 0.01) in older rats. Serum Ca2+ was lower (p &lt; 0.0001) in middle-aged rats compared to young adults. We revealed a 20% incidence of C-cell hyperplasia in older rats and one case of medullary thyroid carcinoma in an old rat. Our findings indicate that the ageing process causes significant histomorphometric changes at the thyroid C-cell level.
Lithium Enhances Autophagy and Cell Death in Skin Melanoma: An Ultrastructural and Immunohistochemical Study
Authors: Taskaeva Iuliia , Gogaeva Izabella , Shatruk Anastasia , Bgatova Nataliya 
Published: May 2022

Abstract
Lithium is an inhibitor of glycogen synthase kinase 3 beta, which is traditionally used in the treatment of bipolar disorders and has antitumor effects. The aim of the current study was to determine if lithium salt causes autophagy and apoptosis in skin melanoma cells to enhance cell death. Light microscopy, transmission electron microscopy, immunohistochemistry, and immunofluorescence were used to study the mechanism of action of lithium carbonate in B16 melanoma cells in vivo. Proliferating cell nuclear antigen immunofluorescence assay revealed that the proliferation of B16 melanoma cells was suppressed by lithium treatment for 7 days. Electron microscopy demonstrated a significant increase in the number of autophagic vacuoles in lithium-treated cells relative to control. In addition, levels of autophagy markers LC3 beta and LAMP1 found in lithium-treated tumor xenografts were higher than levels of these markers in the control tumors. Lithium induced caspase-3 expression and apoptotic cell death in tumor cells. Thus, lithium carbonate is the compound that inhibits cell proliferation and stimulates cell death in melanoma cells through induction of autophagy and apoptosis. Stimulation of autophagy by lithium could contribute to the development of autophagic cell death in tumor cells.
Peer review quality assurance in stereotactic body radiotherapy planning: the impact of case volume
Authors: Huo Michael , Morley Lyndon , Dawson Laura , Bissonnette Jean-Pierre , Helou Joelle , Giuliani Meredith , Berlin Alejandro , Shultz David , Hosni Ali , Shessel Andrea , Waldron John , Barry Aisling 
Published: May 2022

Abstract

Purpose:
Peer review is an essential quality assurance component of radiation therapy planning. A growing body of literature has demonstrated substantial rates of suggested plan changes resulting from peer review. There remains a paucity of data on the impact of peer review rounds for stereotactic body radiation therapy (SBRT). We therefore aim to evaluate the outcomes of peer review in this specific patient cohort.

Methods and materials:
We conducted a retrospective review of all SBRT cases that underwent peer review from July 2015 to June 2018 at a single institution. Weekly peer review rounds are grouped according to cancer subsite and attended by radiation oncologists, medical physicists and medical radiation technologists. We prospectively compiled ‘learning moments’, defined as cases with suggested changes or where an educational discussion occurred beyond routine management, and critical errors, defined as errors which could alter clinical outcomes, recorded prospectively during peer review. Plan changes implemented after peer review were documented.

Results:
Nine hundred thirty-four SBRT cases were included. The most common treatment sites were lung (518, 55%), liver (196, 21%) and spine (119, 13%). Learning moments were identified in 161 cases (17%) and translated into plan changes in 28 cases (3%). Two critical errors (0.2%) were identified: an inadequate planning target volume margin and an incorrect image set used for contouring. There was a statistically significantly higher rate of learning moments for lower-volume SBRT sites (defined as ≤30 cases/year) versus higher-volume SBRT sites (29% vs 16%, respectively; p = 0.001).

Conclusions:
Peer review for SBRT cases revealed a low rate of critical errors, but did result in implemented plan changes in 3% of cases, and either educational discussion or suggestions of plan changes in 17% of cases. All SBRT sites appear to benefit from peer review, though lower-volume sites may require particular attention.
A broad view of pharmaceutical services in multidisciplinary teams of public Primary Healthcare Centers: a mixed methods study in a large city in Brazil
Authors: Mendes Samara Jamile , Farisco Myllena , Leite Silvana Nair , Storpirtis Sílvia 
Published: May 2022

AbstractAim:This study aims to describe how the pharmaceutical services are performed in Primary Healthcare Centers of the Brazilian Public Health System in a large city.Background:There is extensive international discussion about the role of pharmacists in health care teams, particularly in Primary Health Care (PHC). However, in Brazil, there is still no consensus on what services the pharmacist should perform in multidisciplinary teams in PHC.Methods:This study used mixed methods research, and it was conducted with 200 pharmacists who work in PHC Centers of the public health system in São Paulo. The study was conducted using a focus group and an online survey, and qualitative and quantitative data were obtained.Findings:The analysis of the data from the focus group showed two central themes: (i) pharmaceutical services go beyond medicines and (ii) the contributions of the pharmacist to a multidisciplinary team work in PHC. The survey explored 29 services provided by pharmacists, 7 of which were provided daily. It is important to emphasize that pharmacists do not differentiate the relevance attributed to services considered clinical from those that are managerial or more related to access to medicines. This is an opportunity to develop their teamwork skills. Hence, it is necessary to consolidate the professional identity of the pharmacist and to organize their work processes in a multidisciplinary team. PHC is a space that allows a wide development of pharmaceutical services.
Party leadership, electoral reform, and mandate-divide
Authors: Liao Yu-Ceng 
Published: May 2022

AbstractPrevious studies had no consensus on whether a ‘mandate-divide’ exists between district and party-list legislators under the mixed-member system. I argued that previous studies ignored the role of the party. This article aims to explore the legislative consequences of the 2005 electoral reform and the role of parties in Taiwan. I analyzed the roll-call votes, considering abstention and absence as potential defection, along with interviews. The data cover from the fifth to eighth Legislative Yuan, two periods each before and after the electoral reform. The findings show that district legislators tended to defect from the party line than list proportional representation (PR) members in pre- and post-reform periods. However, district legislators only tended to be absent from the voting than list PR members after the electoral reform. Mandate-divide was present throughout the period, but differences were more salient before the reform. Besides, evidence stressing the influence of parties was revealed in the interviews. Party leaders enforce various punishments to enforce party discipline. The role of party became more important after the electoral reform. District legislators have higher absence rate after the electoral reform because they need to engage more in constituency service or avoid expressing their position on controversial issues. The ruling party tends to sanction the absence when they have majority in parliament.
Upper‐Troposphere Saddle‐Like Response to Springtime Surface Sensible Heating Over the Tibetan Plateau: Combined Effect From Baroclinic and Barotropic Process
Authors: Zhao Yu , Sun Ruizao , Xie Zhiang , Duan Anmin 
Published: May 2022

AbstractThe surface sensible heating over the Tibetan Plateau (TP) is a significant, elevated heating source in spring (March‐April‐May, MAM). It exerts considerable thermal effects on both regional and global climate. During MAM, the surface sensible heating over the TP triggers a giant saddle‐like circulation anomaly in the upper troposphere at 200 hPa. Although this structure was observed a long time ago and it contributes to the stationary wave, its formation mechanism remains unclear. Using the Linear Baroclinic Model, we reveal the evolution of this structure in detail. In the initial state, a typical baroclinic anticyclone with a vertical phase tilt forms around the heating source. When the wave propagates downstream due to strong relative vorticity advection and favorable lower level circulation, an anticyclone with a barotropic structure forms downstream. Our analysis indicates that both the barotropic process and baroclinic process contribute to the formation of the saddle‐like structure, and the latter is associated with the spring unique background circulation and vertical heating structure over the TP.