bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dental care for children with Down syndrome: a guide for the dental practice team
Authors: Brosnan Sinéad , Ray-Chaudhuri Emma , Parry Jennifer 
Published: January 2022

Down syndrome is the most common genetic cause of intellectual disability and increases the risk of a range of medical problems that may have implications for oral health. Children diagnosed with Down syndrome should be signposted to dental services as part of their schedule of health checks. To ensure that appropriate access and support are available from the dental team, it is important that dental professionals are familiar with medical and dental conditions and characteristics that occur with increased frequency in patients with Down syndrome. CPD/Clinical Relevance: Down syndrome is the most common chromosomal abnormality likely to present in clinical dental practice. This paper provides guidance for dental professionals for dental checks and surveillance of the developing dentition for children with Down syndrome.
Vitamin D and periodontitis: shedding the light
Authors: Rattu Varkha , Parmar Jay , Raindi Devan 
Published: January 2022

Periodontitis results from dysbiotic periodontal microbiota eliciting an exaggerated host immune-inflammatory response within susceptible individuals. With traditional biofilm management only partially effective, it became apparent that the individual's host response played a pivotal role in the pathogenesis of periodontitis. Specific nutritional factors have been found to impact the host response. Understandably, this has contributed to the emerging shift in contemporary research towards biological approaches to novel periodontal therapies. Vitamin D deficiency, a global public health problem, has been linked to numerous inflammatory conditions including periodontitis. The effects of vitamin D are multifaceted, favouring periodontal health and consideration should be given to its application in clinical practice.CPD/Clinical Relevance: The mechanisms and evidence implicating vitamin D as a host modulator of periodontitis are of relevance in periodontal therapy.
The mother of all battles: Viruses vs humans. Can humans avoid extinction in 50–100 years?
Authors: Diamandis Eleftherios P. 
Published: January 2022

Abstract
The recent SARS-CoV-2 pandemic, which is causing COVID-19 disease, has taught us unexpected lessons about the dangers of human suffering through highly contagious and lethal diseases. As the COVID-19 pandemic is now being partially controlled by various isolation measures, therapeutics, and vaccines, it became clear that our current lifestyle and societal functions may not be sustainable in the long term. We now have to start thinking and planning on how to face the next dangerous pandemic, not just overcoming the one that is upon us now. Is there any evidence that even worse pandemics could strike us in the near future and threaten the existence of the human race? The answer is unequivocally yes. It is not necessary to get infected by viruses found in bats, pangolins, and other exotic animals that live in remote forests to be in danger. Creditable scientific evidence indicates that the human gut microbiota harbor billions of viruses that are capable of affecting the function of vital human organs such as the immune system, lung, brain, liver, kidney, or heart. It is remotely possible that the development of pathogenic variants in the gut can lead to contagious viruses, which can cause pandemics, leading to the destruction of vital organs, causing death or various debilitating diseases such as blindness, respiratory, liver, heart, and kidney failures. These diseases could result in the complete shutdown of our civilization and probably the gradual extinction of the human race. This essay will comment on a few independent pieces of scientific facts, and then combine this information to come up with some (but certainly not all) hypothetical scenarios that could cause human race misery, even extinction, in the hope that these hypothetical scenarios will trigger preventative measures that could reverse or delay the projected adverse outcomes.
From ‘clubs’ to ‘clocks’: lexical semantic extensions in Dene languages
Authors: Snoek Conor 
Published: January 2022

AbstractThis study examines the semantics of a root form underlying a wide range of Dene lexical expressions. The root evolved from a simple nominal denoting “club” to expressions lexicalizing the movement of stick-like objects and the rotation of helicopter blades. These semantic extensions arise through source-in-target and target-in-source metonymies. Drawing on Cognitive Linguistics, especially the theory of metonymy, offers a method of describing the range of meanings expressed by this root in a concise manner. Focusing on the results of metonymic meaning extensions also opens the way to addressing questions in the history of Dene languages. This study contributes to increasing the typological scope of Cognitive Linguistic approaches and argues for the usefulness of the theory in addressing problems in Dene linguistics.
“Resources at Hand, Head, and Heart”: ‘Heightened Habitus’ as an Endogenous Resource in Immigrant Entrepreneurial Bricolage
Authors: Griffin-EL Eliada , Olabisi Joy 
Published: January 2022

Abstract
Bricolage is commonly recognized as a practice of non-traditional resource mobilization by immigrant entrepreneurs within their country of residence. When the host country is in an adversarial social and institutional context characterized by the liability of foreignness, we posit that accessing “resources at hand” in the external environment is hampered by anti-immigrant sentiments, both socially and institutionally. Through a rigorous analysis of eight cases of immigrant entrepreneurs and their South African-based enterprises, we apply Bourdieu’s theory of practice to examine the practice of bricolage at a more nuanced level. Our findings suggest that the localized prejudice against immigrants ‘otherizes’ their foreignness, and in turn, heightens the entrepreneurs’ awareness of their habitus. We argue that the immigrants’ ‘heightened habitus’ represents an internalization of both cognitive (i.e. resources at head) and adaptive (i.e. resources at heart) dispositions informed by the home country, and which serve as crucial endogenous resources by which to reimagine and reconstruct external resources accessed via local social capital. We present the novel theoretical contribution of immigrant entrepreneurial bricolage as the utilization of both endogenous resources at head and heart, which are activated by – and intended to overcome – their liability of foreignness. Our contribution also aims to reconstruct the frequently referenced exogenous resources at hand.
A severe oxaliplatin immune-induced syndrome after oxaliplatin-based pressurized intraperitoneal aerosol chemotherapy (PIPAC)
Authors: Ezanno Anne-Cecile , Malgras Brice , Aoun Olivier , Delarge Amaury , Doreille Alice , Pocard Marc 
Published: January 2022

Abstract

Objectives
Oxaliplatin immune-induced syndrome (OIIS) was recently recognized as an uncommon complication of oxaliplatin therapy.

Methods
We report an exceptionally OIIS after pressurized intraperitoneal aerosol chemotherapy (PIPAC).

Results
Our patient developed a severe OIIS probably related to the intraperitoneal administration of oxaliplatin. Specific tests were performed and detected high-titer antibodies to oxaliplatin.

Conclusions
The OIIS is a rare. Physicians had to be aware of that clinical situation because it could be reversible, even in case of peritoneal advanced disease, and ICU treatment is justified.
Finance for Green Chemistry through Currency Mix
Authors: Watanabe Joji 
Published: January 2022

Abstract
Introduction of green chemistry will require a large sum of finance to conduct basic research and develop applications at various research institutes in the public and private sector. To meet the financial needs, the author suggests a change in the currency system commonly applied in most countries to a mix of debt currency and equity currency, in which the latter means currency directly issued by the government, thereby avoiding arguments on the upper limit of government bond issuance. In most advanced economies potentially with large excess supply capacities, bad inflation never takes place as long as workers can work in peace under good securities, and as long as additional budget can be used in proper manners. This new currency issuance system for sufficient public funding will not only support research and realization of green chemistry, but also solve social problems by assisting the underprivileged, etc.
Inequality in Education: A Comparison of Australian Indigenous and Nonindigenous Populations
Authors: Gunawan David , Griffiths William , Chotikapanich Duangkamon 
Published: January 2022

Abstract
Data from the Household Income and Labour Dynamics in Australia Survey is used to estimate distributions for the level of educational attainment for Australian indigenous and nonindigenous populations for the years 2001, 2006, 2014 and 2017. Bayesian inference is used to analyse how these ordinal categorical distributions have changed over time and to compare indigenous and nonindigenous distributions. Both the level of educational attainment and inequality in educational attainment are considered. To compare changes in levels over time, as well as inequality between the two populations, first order stochastic dominance and an index of educational poverty are used. To examine changes in inequality over time, two inequality indices and generalised Lorenz dominance are considered. Results are presented in terms of posterior densities for the indices and posterior probabilities for dominance for the dominance comparisons. We find some evidence of improvement over time, especially in the lower parts of the indigenous distribution and that inequality has significantly increased from 2001 to 2017.
Structural characterization of benzketozone monohydrate
Authors: Tillaeva Umida , Ashurov Jamshid , Tillaeva Gulnora , Nabiev Abdusamat , Sabirov Vahobjon 
Published: January 2022

Abstract
The structure of benzketozone monohydrate, C9H9N3O2S·H2O (BKZ), was studied by single-crystal X-ray diffraction, quantum chemical (DFT) and IR spectroscopy methods. The nitrogen atoms of the amino and imine groups of the thiosemicarbazide fragment are stabilized in the cis-configuration. The bond length N–C in the thiosemicarbazide group is unusually short (1.306(3) Å) as a result of the p,π-conjugation in that group. The hydrogen bonds and other weak interactions are studied by Hirshfeld surface calculations. The geometrical parameters of the structures were optimized by density functional theory.
Circulating miR-21-5p, miR-146a-5p, miR-320a-3p in patients with atrial fibrillation in combination with hypertension and coronary artery disease
Authors: Vasiliev S. V. , Akselrod A. S. , Zhelankin A. V. , Schekochikhin D. Yu. , Generozov E. V. , Sharova E. I. , Stonogina D. A. 
Published: January 2022

Aim. To study the plasma profiles of circulating extracellular microribonucleic acids (miRNAs), potentially including in pathogenesis of cardiovascular diseases, in patients with atrial fibrillation (AF) in combination with hypertension (HTN) or coronary artery disease (CAD).Material and methods. The study included patients with AF in combi nation with HTN (n=21) or CAD (n=10), as well as following control groups: patients with uncomplicated HTN without AF (n=28), patients with stable CAD without AF (n=10) and healthy individuals (n=30). MiRNA samples were isolated from blood plasma of the study participants. MiRNAs were detected by TaqMan quantitative polymerase chain reaction assay. The relative plasma levels of five candidate miRNAs were estimated relative to the reference miR-16-5p.Results. Among the analyzed circulating plasma miRNAs, a higher level of miR-320a-3p was associated with AF, while increased levels of miR 146a-5p and miR-21-5p are potentially associated with presence of both AF and CAD.Conclusion. Differences were found in the plasma miRNA profiles (miR-21-5p, miR-320a-3p, miR-146a-5p) between patients with AF, regardless of concomitant disease (CAD or HTN), and healthy individuals in the control group.
Effect of salt intake on clinical course and hemodynamics in patients with hypertrophic cardiomyopathy
Authors: Poteshkina N. G. , Krylova N. S. , Maslova M. Y. , Kovalevskaya E. A. , Svanadze A. M. 
Published: January 2022

Aim. To evaluate the relationship between the salt intake (NaCl) and the clinical and hemodynamic parameters in patients with hypertrophic cardiomyopathy (HCM).Material and methods. Forty four patients with HCM (mean age, 60,4±15,3 years) were examined. Particular attention was paid to intraventricular obstruction and hypovolemic syncope. NaCl consumption was estimated by 24-hour urine sodium test.Results. An inverse correlation was found between syncope and 24-hour natriuresis (r=-0,3, p=0,04). At 24-hour natriuresis <50 mmol/day, syncope was more common (p=0,02): odds ratio (OR), 12,3 (95% confidence interval (CI): 1,3-121,3, p=0,03), as well as <65 mmol/day (p=0,04): OR, 8,3 (95% CI: 1,13-60,3; p=0,04). At higher 24-hour urine sodium values, no reduction in syncope risk was recorded. A correlation was found between low values of left ventricular (LV) stroke volume index (SVI) (<26 ml/m2) and 24-hour urine sodium (<50 mmol/day) (r=0,5, p=0,01). An inverse correlation was observed between LV SVI and syncope at 24-hour natriuresis <50 mmol/day (r=-0,9; p=0,05). An inverse relationship was found between the intraventricular obstruction and 24-hour urine sodium (r=-0,4, p=0,01). The prevalence of obstruction increased as natriuresis decreased: at 120 mmol/day, OR was 4,3 (95% CI: 1,01-18,6, p=0,048), at 110 mmol/day, OR — 4,6 (95% CI: 1,218,1, p=0,03), and at 100 mmol/day, OR — 4,0 (95% CI: 1,1-11,7, p=0,04). An increase in 24-hour urine sodium >130 mmol/day was not followed by a further decrease in obstruction prevalence.Conclusion. To reduce the obstruction risk, the optimal 24-hour urine sodium level is ≥130 mmol/day (NaCl, 7,5 g/day). To reduce the syncope risk, regardless of obstruction presence, the optimal level of 24-hour natriuresis is ≥65 mmol/day (NaCl, 3,8 g/day).
Intracoronary epinephrine and verapamil in the refractory no-reflow phenomenon in patients with acute myocardial infarction
Authors: Dil S. V. , Vyshlov E. V. , Ryabov V. V. 
Published: January 2022

Despite modern advances in performing percutaneous coronary interventions, refractory no-reflow remains a serious problem that worsens in-hospital and long-term prognosis. Low-dose adrenaline may exhibit potent beta-receptor agonist properties that mediate coronary vasodilation.Aim. To evaluate the efficacy and safety of intracoronary administration of epinephrine and verapamil, as well as their combination, compared with standard treatment in patients with ST-segment elevation myocardial infarction (STEMI) and refractory no-reflow during percutaneous coronary interventions.Material and methods. Patients with STEMI and refractory no-reflow will be randomized into 4 groups: standard therapy, intracoronary adrenaline, intracoronary verapamil, intracoronary epinephrine + verapamil. All patients will be assessed for epicardial blood flow using the Thrombolysis in Myocardial Infarction (TIMI) and Myocardial Blush Grade (MBG) scales, peak troponin levels, ST segment changes, echocardiography, magnetic roesnance imaging, and dynamic single photon emission computed tomography.Results. Based on the pharmacodynamic effects of epinephrine and verapamil, their combination is expected to have a more potent vasodilating effect.Conclusion. If the Intracoronary administration of EPInephrine and VERapamil in the refractory no-reflow phenomenon (EPIVER) study will be successful, a novel, more effective method for managing refractory no-reflow phenomenon will appear. This will ensure better preservation of left ventricular systolic function, as well as improve the prognosis and clinical course of the disease.
Caustics of developable surfaces
Authors: Hoffmann Miklós , Juhász Imre , Troll Ede 
Published: January 2022

AbstractWhile considering a mirror and light rays coming either from a point source or from infinity, the reflected light rays may have an envelope, called a caustic curve. In this paper, we study developable surfaces as mirrors. These caustic surfaces, described in a closed form, are also developable surfaces of the same type as the original mirror surface. We provide efficient, algorithmic computation to find the caustic surface of each of the three types of developable surfaces (cone, cylinder, and tangent surface of a spatial curve). We also provide a potential application of the results in contemporary free-form architecture design.
PRESENTACIÓN-SEIS MIRADAS SOBRE UN TESORO: ALISEDA, 1920-2020
Authors: RODRÍGUEZ DÍAZ ALONSO , PAVÓN SOLDEVILA IGNACIO , DUQUE ESPINO DAVID M. 
Published: January 2022

Como toda conmemoración, el centenario del hallazgo del Tesoro de Aliseda invitaba a la celebración, la reflexión y el balance. Sin embargo, truncados
los eventos por la funesta pandemia padecida, solo la reflexión y el balance han sido viables en el tiempo confinado que vivimos, entre cuyas rendijas se han
deslizado las “Seis miradas sobre un tesoro: Aliseda, 1920-2020” que conforman este Dossier.
LOS ECOS DEL TESORO DE ALISEDA EN LAS DAMAS Y EN LAS OFERENTES IBÉRICAS
Authors: ARANEGUI GASCÓ Carmen 
Published: January 2022

Este artículo considera el Tesoro de Aliseda como la primera ostentación conjunta masculina y femenina de la península ibérica. Plantea la relación de la orfebrería extremeña con la ibérica. Ambas comparten tipologías hasta el siglo IV a.C. y la diadema frontal se proyecta varios siglos más, como uno de los signos de prestigio femenino ibérico, presente en las esculturas hasta la época de la romanización.
EL TESORO FENICIO DE ALISEDA
Authors: ORTI BELMONTE Miguel Ángel 
Published: January 2022

Este trabajo fue redactado por M. Ángel Orti Belmonte (1891-1973) en los meses inmediatos al descubrimiento del Tesoro de Aliseda (Cáceres), ocurrido el 29 de febrero de 1920. Desde entonces ha permanecido inédito. Su original junto a una primera versión y otros documentos de interés para su contextualización se encuentran en la Fundación “Lucio Gil de Fagoaga” (Requena, Valencia)i. Su publicación cien años después en este Dossier enriquece la historiografía de este célebre hallazgo y sus confusas circunstancias. Asimismo, su análisis complementario ofrece una nueva lectura sobre el conflicto que mantuvieron Orti Belmonte y J. Ramón Mélida por la publicación en primicia de las joyas.
MELILLA Y LA LEY DE EXTRANJERÍA DE 1985. TRASCENDENCIA INTERNACIONAL DE UN CONFLICTO LOCAL. ANÁLISIS DE TRES PERIÓDICOS
Authors: RUBIANO SEGOVIA Sonia 
Published: January 2022

La ley de Extranjería de 1985 no había tenido en cuenta a las miles de personas que habían nacido o vivían en Melilla desde hacía varias generaciones, pero que no tenían ningún derecho como ciudadanos. Bajo el liderazgo de Aomar Mohamedi Duddú, el colectivo musulmán de Melilla se movilizó para reclamar su derecho a obtener la nacionalidad española. El objetivo de este artículo es analizar la imbricación de este conflicto, que se desarrolló entre 1985 y 1987, y que era a priori local, con las reclamaciones territoriales de Marruecos, y la dimensión internacional que alcanzó, a través del análisis de lo que al respecto publicaron tres periódicos de tirada nacional: ABC, El País y La Vanguardia a lo largo de esos años.
Processo de Homogeneização de Carne Bovina: Características Microbiológicas
Authors: Palermo Mendes Janaína , Prudente Serafim Flávia , Valentim Jean Kaique , Freitas Silva Ariadne 
Published: January 2022

A carne moída bovina é um produto de alto valor nutricional e em função do problema de conservação que favorece a oxidação, além de temperaturas inadequadas e falhas nas condições de higiene, proporciona um ambiente de proliferação de bactérias, tornando-se um produto nocivo à saúde. Este trabalho tem como intuito, por meio de uma revisão de literatura atualizada, identificar o grau de importância de informações diretamente relacionadas à qualidade e particularidades no processamento da carne bovina homogeneizada. Por se tratar de um produto alimentício de fácil preparo e aquisição, a biosseguridade deve ser procedida através de uma abordagem integrada em que se considere toda a cadeia de produção. A excessiva manipulação do produto e as condições de temperatura são um dos principais problemas da carne moída, já que este produto cárneo passa por oxidação lipídica, à medida que a temperatura vai se elevando após o processo de homogeneização, há um acelerado aumento das reações químicas e enzimáticas na musculatura, favorecendo o crescimento de micro-organismos como as bactérias gram-negativas como Enterobacteriaceae Pseudomonas e por Gram-positivas: Enterococcus, Lactobacillus e Staphylococcus propiciam o aparecimento de bactérias patogênicas como Clostridium perfringens, S. aureus, Salmonella sp., e também alguns sorotipos de Escherichia coli e, ocasionalmente, Yersinia enterocolitica, Clostridium botulinum e Bacillus cereus.

Palavras-chave: Carne Moída. Processamento. Qualidade. Segurança Alimentar.

Abstract
Ground beef is a product of high nutritional value and due to the conservation problem that favors oxidation in addition to inadequate temperatures and flaws in hygiene conditions, it provides an environment for the bacteria proliferation , making it a harmful product to health. This work aims to, through an updated literature review, identify the degree of importance of information directly related to the quality and particularities in the homogenized beef processing. Because it is a food product that is easy to prepare and purchase, biosecurity must be pursued through an integrated approach that considers the entire production chain. The excessive product handling and the temperature conditions is one of the main problems of ground beef, since this meat product undergoes lipid oxidation and as the temperature rises after the homogenization process, there is an accelerated increase in chemical and enzymatic reactions in the musculature, favoring the growth of microorganisms such as gram-negative bacteria namely: Enterobacteriaceae Pseudomonas and by Gram-positive: Enterococcus, Lactobacillus and Staphylococcus, propitiate the appearance of pathogenic bacteria such as Clostridium perfringens, S. aureus, Salmonella sp., and also some Escherichia coli serotypes and, occasionally, Yersinia enterocolitica, Clostridium botulinum and Bacillus cereus.

Keywords: Food Security. Ground Beef. Processing, Quality.