bluuebunny/crossref_metadata_2025_split huggingface dataset:
Agrobiological evaluation of collection of vegetable soybean varieties in the Forest-Steppe of Ukraine
Authors: Yatsenko V. , Poltoretskyi S. , Yatsenko A. 
Published: December 2021

Purpose. Agrobiological assessment of soybean varieties Glycine max var. Shirofumi on a complex of economically valuable traits for introduction in the conditions of the Forest-Steppe of Ukraine. Selection of promising breeding forms based on morpho-biological and physiological-biochemical characteristics.
Methods. Field, laboratory, statistical, computatio­nal and analytical. The studies were carried out in the conditions of the educational and production department of Uman National University of Horticulture during 2020–2021, using collection varieties of different ecological and geographical origin (Ukraine, Belarus, Sweden, Japan and Russia). The cultivars were assessed according to the following parameters: plant height, leaf area, net productivity of photosynthesis and indices of individual productivity (weight of beans per plant, number of seeds in a bean, etc.), productivity of green beans and biologically mature seeds and, accordingly, quality indicators of production (dry matter, sugar and protein content). The counts were carried out in the phase of the technical ripeness of the beans.
Results. The variability of the “plant height” trait of the studied varieties had an average variation – the coefficient of variation was 22%. The results showed that the standard cultivar ‘Romatnyka’ and the collection cultivars ‘Karikachi’ and ‘Astra’ belong to the semi-determinant type of growth (97–109 cm), cultivar ‘Fiskeby V’, ‘L 380-2-13’, ‘Fiskeby V-E5’, ‘SibNIISOKh 6’, ‘Sac’, ‘Vesta’ belong to the determinant type of growth. According to the number of seeds in the pod, the studied varieties were clearly divided into two groups: with two-seeded beans (varieties ‘Karikachi’, ‘Astra’, ‘L 380-2-13’) and three-seeded beans [varieties ‘Romatnyka’ (standard), ‘Fiskeby V’, ‘Vesta’, ‘SibNIISOX 6’, ‘Sac’, ‘Fiskeby V-E5’]. The maximum yield of edamame beans was produced by varieties ‘L 380-2-13’ (17.3 t/ha), ‘Vesta’ (18.8 t/ha), ‘Sac’ (19.6 t/ha), ‘Fiskeby V’ (21.4 t/ha), ‘Fiskeby V-E5’ (22.4 t/ha). A significant differentiation of soybean varieties in the biochemical composition of immature beans was revealed. The dry matter content was 22.70–31.70%. The share of protein in edamame green beans was 28.2–38.6%, in biologically mature seeds its share increased to 36.1–42.8%. Among soluble sugars, the highest concentration was noted for sucrose – 7.70–9.38 mg/100 g in dry seeds, what in average amounted to 81.6–86.2% of all sugars. The presented results provide a comprehensive assessment of breeding work on soybean varieties with a low content of oligosaccharides.
Conclusions. Evaluation of collection varieties of vegetable soybeans by the variability of morphological traits and productivity made it possible to distinguish ‘Sac’ variety by a complex of valuable traits for creation of new varieties of vegetable soybeans adapted to the conditions of the Forest-Steppe of Ukraine.
Statistical approaches to explore the linkages between physicochemical parameters and BQEs, and set river nutrient threshold concentrations in Hungary
Authors: Szomolányi O. , Clement A. 
Published: December 2021

Abstract
The objective of the Water Framework Directive (WFD) is to achieve good ecological status in surface waters by 2027. To make a proper evaluation of the ecological status of watercourses, it is necessary to harmonize class boundaries for chemical and biological quality elements (BQEs). This paper aims to explore the linkages between physicochemical parameters and BQEs and set river nutrient threshold concentrations that support good ecological status. Regression and mismatch methods were applied to find the relationship between phytoplankton (PP) and phytobenthos (PB) ecological quality ratio and mean total phosphorus (TP) and total nitrogen (TN) concentrations. Nutrient thresholds have been suggested for several water types, which are varied in the case of highland rivers 1.8–6.2 mg TN/l, 180–400 μg TP/l; in the case of lowland rivers 1.4–5.0 mg TN/l, and 100–350 μg TP/l. These values are similar to what other studies found, but the relationship between biology and nutrients was weaker. Besides nutrients, additional data of measured dissolved organic carbon, 5-day biochemical oxygen demand, chemical oxygen demand with potassium permanganate method, and information about hydromorphological features were involved in the analysis. The research demonstrates that random forest can be used as a nonlinear, multiparametric model for predicting biological class from five variables with 35–81% error for PP and with 18–47% error for PB.
A new method for dividing flood period in the variable-parameter Muskingum models
Authors: Akbari Reyhaneh , Hessami-Kermani Masoud-Reza 
Published: December 2021

Abstract
The Muskingum routing model is favored by water engineers owing to its simplicity and accuracy. A large amount of research is done to improve the accuracy of the model. One way to do so is to consider variable hydrological parameters during the flood routing period. In this study, the random selection (RS) method was proposed to divide the flood period of the nonlinear Muskingum model into three sub-periods. The proposed method was based on RS of members in each sub-region. It was applied to rout three flood hydrographs, and the objective function was the sum of squared errors. Comparing the results from the three variable-parameter nonlinear Muskingum model with those from the variable-parameter nonlinear Muskingum models in previous studies, the proposed model optimized the objective function in these hydrographs up to 61%. The uncertainty analysis of Muskingum parameters for Wilson's hydrograph was performed by the fuzzy alpha cut method, and it was found that the uncertainty of the parameter x is greater than the uncertainty of the parameters k and m.
An estimation of the evapotranspiration of typical steppe areas using Landsat images and the METRIC model
Authors: Wang Jun , Li Heping , Lu Haiyuan 
Published: December 2021

Abstract
Remote sensing excels in estimating regional evapotranspiration (ET). However, most remote sensing energy balance models require researchers to subjectively extract the characteristic parameters of the dry and wet limits of the underlying surfaces. The regional ET accuracy is affected by wrong determined ideal pixels. This study used Landsat images and the METRIC model to evaluate the effects of different dry and wet pixel combinations on the ET in the typical steppe areas. The ET spatiotemporal changes of the different land cover types were discussed. The results show that the surface temperature and leaf area index could determine the dry and wet limits recognition schemes in grassland areas. The water vapor flux data of an eddy covariance system verified that the relative error between the ETd,METRIC and ETd,GES of eight DOYs (day of the year) was 18.8% on average. The ETMETRIC values of the crop growth season and the ETIMS of eight silage maize irrigation monitoring stations were found to have a relative error of 11.1% on average. The spatial distribution of the ET of the different land cover types in the study area was as follows: ETwater &gt; ETarable land &gt; ETforest land &gt; ETunutilized land &gt; ETgrassland &gt; ETurban land.
Identification of the most appropriate adaptation for rice and wheat in the face of climate change in eastern India
Authors: Dubey Madhuri , Mishra Ashok , Singh Rajendra 
Published: December 2021

AbstractThe changing climate affects natural resources that impart a negative impact on crop yield and food security. It is thus imperative to identify agro-climate wise, area-specific adaptation options to ensure food security. This study, therefore, evaluated some feasible adaptation options for two staple food grain crops, rice and wheat, in different agro-climatic regions (ACRs) of Eastern India. Alteration in transplanting date, seedling age, and fertilizer management (rate and split of fertilizer) for rice; and sowing date, fertilizer management, and deficit irrigation scheduling for wheat, are assessed as adaptation options. The crop environment and resource synthesis (DSSAT) model is used to simulate the crop yield using different plausible adaptation options to projected climate scenarios. Findings show that shifting transplanting/sowing date, and nitrogen fertilizer application at 120% of recommended nitrogen dose with four splits could be an effective adaptation for rice and wheat crops. Results also emphasize that transplanting of 18 days older seedlings may be beneficial in rice cultivation. In contrast, irrigation at a 30–40% deficit of maximum available water would sustain the wheat yield under climate change conditions. This study suggests the best combination of adaptation options under climate change conditions in diverse ACRs, which may assist agriculturists in coping with climate change.
Propranolol degradation through processes based on the generation of hydroxyl free radical
Authors: Nájera-Aguilar Hugo Alejandro , Mayorga-Santis Rosario , Gutiérrez-Hernández Rubén Fernando , Santiesteban-Hernández Antonio , Rodríguez-Valadez Francisco J. , Ulloa-Gutiérrez Diego Alberto , Araiza-Aguilar Juan Antonio , Cruz-Salomón Abumalé 
Published: December 2021

Abstract
Pharmaceutical substances such as propranolol (PRO) are an emerging class of aquatic contaminants that have increasingly been detected in ground and surface water. For this reason, the aim of this study was to evaluate the efficiency of advanced oxidation systems for the PRO degradation. The tests started with anodic oxidation (AO), using 0.01, 0.05, and 0.1 M Na2SO4 as the supporting electrolyte and 16, 32, 48, and 64 mA cm−2 as current density. Under the best conditions obtained in AO, the electro-Fenton (EF) process was reviewed, where the effect of Fe2+ was analyzed with 5, 10, 15, and 20 mg Fe2+ L−1. The Fenton reaction (FR) was studied using the Fe2+ concentration that promoted the highest percentage of PRO removal and initial concentration of 16 mg L−1 of H2O2, in addition to these conditions, in the photo-Fenton (PF) system, the effect of UV light with wavelengths 254 and 365 nm were evaluated. The results obtained showed that the degradation efficiency of the EF &gt; AO &gt; PF &gt; FR system along with a percent removal of 94.52, 90.4, 25.97, and 4.4%, respectively. The results showed that PRO can be removed through the studied systems, with the EF system being the most efficient.
Recent advances, influencing factors, and future research prospects using photocatalytic process for produced water treatment
Authors: Amakiri Kingsley Tamunokuro , Angelis-Dimakis Athanasios , Ramirez Canon Anyela 
Published: December 2021

Abstract
Oilfield-produced water is the primary by-product generated during oil and gas extraction operations. Oilfield-produced water is often severely toxic and poses substantial health, safety, and environmental issues; adequate treatment technologies can bring these streams to a quality level. Photocatalysis is a photochemical catalytic reaction that is a highly promising tool for environmental remediation due to its efficiency in mineralizing persistent and potentially toxic contaminants. However, there is limited understanding of its application to treat oilfield-produced water with a complex and highly variable water composition. This review article discusses the mechanisms and current state of heterogeneous photocatalytic systems for oilfield-produced water treatment, highlighting impediments to knowledge transfer, including the feasibility of practical applications and the identification of essential research requirements. Additionally, the effects of significant variables such as catalyst quantity, pH, organic compound concentration, light intensity, and wavelength are discussed in detail. Some solutions are proposed for scientists and engineers interested in advancing the development of industrial-scale photocatalytic water treatment technologies.
Tecnologia assistiva e inclusão escolar: mediação e autonomia em questão
Authors: Bisol Cláudia Alquati , Valentini Carla Beatris 
Published: December 2021

Este artigo tem como objetivo contribuir para a inclusão de alunos com deficiência, com base na análise e discussão de dois casos em que a mediação no uso de Tecnologia Assistiva (TA) potencializou a aprendizagem e a constituição da autonomia. São utilizados diários de campo construídos ao longo de reuniões na escola e registros escolares como fontes de dados. Os diários permitem acessar narrativas orais que emergem espontaneamente no cotidiano escolar. O primeiro caso retrata a dificuldade de um menino com deficiência física, no uso de sua cadeira de rodas. O segundo caso refere-se à interação comunicativa de um menino com Transtorno do Espectro Autista. O modo como a criança se apropria da TA, significa suas vivências cotidianas e constitui sua relação com os objetos e com os outros, possibilita que movimentos em direção à autonomia sejam construídos. O processo, porém, depende da mediação na interação com elementos culturalmente criados e com sujeitos sociais.
Stem Cell-based Therapeutic and Diagnostic Approaches in Alzheimer's
Disease
Authors: Abdi Sadaf , Javanmehr Nima , Ghasemi-Kasman Maryam , Bali Hanie Yavarpour , Pirzadeh Marzieh 
Published: December 2021

Background:
Alzheimer’s disease (AD) is a neurodegenerative impairment
mainly recognized by memory loss and cognitive deficits. However, the current therapies against AD are mostly limited to palliative medications, prompting researchers to investigate more efficient therapeutic approaches for AD, such as stem cell therapy. Recent evidence has proposed that extensive neuronal and synaptic loss and altered adult neurogenesis, which is perceived pivotal in terms of plasticity and network maintenance, occurs early in the course of AD, which exacerbates neuronal vulnerability to AD. Thus, regeneration and replenishing the depleted neuronal networks by strengthening the endogenous repair mechanisms or exogenous stem cells and their cargoes is a rational therapeutic approach. Currently, several stem cell-based therapies as well as stem cell products like exosomes, have shown promising results in the early diagnosis of AD.

Objective:
This review begins with a comparison between AD and normal aging
pathophysiology and a discussion on open questions in the field. Next, summarizing the current
stem cell-based therapeutic and diagnostic approaches, we declare the advantages and
disadvantages of each method. Also, we comprehensively evaluate the human clinical trials of
stem cell therapies for AD.

Methodology:
Peer-reviewed reports were extracted through Embase, PubMed, and Google
Scholar until 2021.

Results:
With several ongoing clinical trials, stem cells and their derivatives (e.g., exosomes) are
an emerging and encouraging field in diagnosing and treating neurodegenerative diseases.
Although stem cell therapies have been successful in animal models, numerous clinical trials in
AD patients have yielded unpromising results, which we will further discuss.
Phytoconstituents of Lantana camara L.: Rekindling Hope in the Cancer
Treatment
Authors: Dhobi Mahaveer , Kathuria Ishita , Joshi Mit , Patel Bhoomika M. 
Published: December 2021

Background:
Lantana camara L. belongs to the family Verbenaceae. It originated in
Tropical America in Southern Georgia and the North of Texas, and was introduced in Calcutta, India,
in the year 1809 as an ornamental hedge. The plant L. camara is also distributed in Southeast
Asia, China, Australia, Brazil, West Indies, Kenya, Mexico, East Africa, and Tanzania. Many of its
phytoconstituents possess medicinal properties which are used traditionally to treat fever, uterine
hemorrhage, and excess menstrual discharge, chronic ulcers, rheumatism, gonorrhea, toothache,
gastrointestinal pain, etc., and it has been used in Brazil for curing malaria, mange, headaches,
colds, and fevers.

Objective:
The review elaborates traditional practices related to Lantana camara L., its phytochemistry,
and its role in various types of cancers.

Methods:
The data on L. camara were collected through different online databases, like Web of
Science, PubMed, Science Direct, Springer, and Google Scholar.

Results:
Major phytoconstituents isolated from the plant shows anticancer activity, especially lantadene
A-D, icterogenin, oleanolic acid, lantacamaric acid A, B, oleanonic acid, etc. In vitro and in
vivo studies demonstrate the potential of the plant for various cancers. Certain extracts, isolated
compounds, and their semi-synthetic derivatives have depicted a significant cytotoxic and anti-proliferative
effect.

Conclusion:
Clinical studies related to the therapeutic efficacy of Lantana camara L. are not yet
established, therefore, making it crucial to direct future researches in this area.
Co-infection Paragonimiasis-pulmonary Tuberculosis Discovered from a Man in Abidjan, Côte d’Ivoire: Case Report
Authors: David AKA N’da Angbeletchi , Coulibaly Fatoumata , Ehouman Mocket Adolphe , Dadie Ettawa Alphonse 
Published: December 2021

Introduction:
Paragonimiasis is a very uncommon zoonosis in sub-Saharan Africa. It is a trematodial disease contracted by eating fresh or undercooked crustaceans harboring a parasite of the genus Paragonimus. About fifteen species of Paragonimus are pathogenic to humans. In Africa, three species are frequently encountered: Paragonimus africanus, Paragonimus uterobilatéralis, and Paragonimus westermani. Clinically, it has similarities with pulmonary tuberculosis so that confusion is quickly made.

Case Report:
We report here a case of paragonimiasis discovered incidentally in a security guard man, 26 years old, originated from Côte d’Ivoire, who consulted in 2019 to the Medical Teaching Hospital of Cocody, for hemoptysis under a chronical mode.

Results:
After examination, the disease of paragonimiasis was diagnosed by positive direct smear. Otherwise, patient was positive to TB after a molecular test.
An anti-tuberculosis cure was proposed, and a treatment with praziquantel 600 mg (2 tabs x3 / d for 4 days) allowed us to obtain biological cure without major side effects for paragonimiasis.

Conclusion:
The diagnostic issues of paragonimiasis constitute a great challenge for health systems already weakened by the instability due to covid-19 pandemic. The insufficient resources allocated to the health sector showing the lack of integration of the diagnostics of paragonimiasis to pulmonary tuberculosis program are crucial.
The strengthening of human resources, as well as the improvement of the technical platform of reference laboratories in regions, are really needed.
The Training of Undergraduate Medical Students in General Medical Practice and Primary Health Care: A Scoping Review
Authors: Mabuza Langalibalele Honey , Darong Gabriel Gyang , Makhudu Sbongile Joyce , Drysdale Roisin E. , Moshabela Mosa 
Published: December 2021

Background:Undergraduate medical students are trained to acquire a general medical practice overview on qualifying. This training forms a foundation for primary health care service or further training towards a specialty of choice.Objective:The aim of the study was to determine the scope of published scientific literature on the training of undergraduate medical students in “general medical practice” and “primary health care,” exploring how these two concepts are understood, the pedagogical approaches employed by the trainers, the training platforms and the challenges encountered during the training.Methods:The review followed the five steps recommended by Arksey and O’Malley. Using the specified eligibility criteria, the research team systematically screened titles, abstracts, and full articles. Data were entered into Google Forms spreadsheets, which was followed by inductive data analysis of key themes.Results:130 articles were eligible for inclusion in the study. Thematic analysis yielded eight themes: definition of “general medical practice” and “PHC”, pedagogical approaches (conventional, PBL, teams and CBME), training platforms (tertiary and rural), medical students’ trainers (faculty, GPs and patients), training content, trainers’ and trainees’ perceptions, and challenges encountered.Conclusion:This scoping review has revealed that general medical practice and primary health care are approaches to holistic patient care taught at undergraduate medical training. Primary health care and general medical training are mainly undertaken in GP practices and rural settings. Competency-based medical education is emerging as an appropriate pedagogical method towards ‘fit-for-purpose’ training. The inclusion of patients as trainers in general medical practice and primary health care is yielding positive results.
Modeling Years of Life Lost Due to COVID-19, Socioeconomic Status, and Nonpharmaceutical Interventions: Development of a Prediction Model
Authors: John Jari 
Published: December 2021

Background
Research in the COVID-19 pandemic focused on the health burden, thereby largely neglecting the potential harm to life from welfare losses.

Objective
This paper develops a model that compares the years of life lost (YLL) due to COVID-19 and the potential YLL due to the socioeconomic consequences of its containment.

Methods
It improves on existing estimates by conceptually disentangling YLL due to COVID-19 and socioeconomic status. By reconciling the normative life table approach with socioeconomic differences in life expectancy, it accounts for the fact that people with low socioeconomic status are hit particularly hard by the pandemic. The model also draws on estimates of socioeconomic differences in life expectancy to ascertain potential YLL due to income loss, school closures, and extreme poverty.

Results
Tentative results suggest that if only one-tenth of the current socioeconomic damage becomes permanent in the future, it may carry a higher YLL burden than COVID-19 in the more likely pandemic scenarios. The model further suggests that the socioeconomic harm outweighs the disease burden due to COVID-19 more quickly in poorer and more unequal societies. Most urgently, the substantial increase in extreme poverty needs immediate attention. Avoiding a relatively minor number of 4 million unemployed, 1 million extremely poor, and 2 million students with a higher learning loss may save a similar amount of life years as saving 1 million people from dying from COVID-19.

Conclusions
Primarily, the results illustrate the urgent need for redistributive policy interventions and global solidarity. In addition, the potentially high YLL burden from income and learning losses raises the burden of proof for the efficacy and necessity of school and business closures in the containment of the pandemic, especially where social safety nets are underdeveloped.