bluuebunny/crossref_metadata_2025_split huggingface dataset:
The First Evaluation of Remote Magnetic Navigation-Guided Pediatric Ventricular Arrhythmia Ablation
Authors: Noten Anna M. E. , Ramdat Misier Nawin L. , Kammeraad Janneke A. E. , Wijchers Sip , Van Beynum Ingrid M. , Dalinghaus Michiel , Krasemann Thomas B. , Yap Sing-Chien , de Groot Natasja M. S. , Szili-Torok Tamas 
Published: April 2022

AbstractCatheter ablation (CA) is an important treatment option for ventricular arrhythmias (VA) in pediatric cardiology. Currently, various CA techniques are available, including remote magnetic navigation (RMN)-guided radiofrequency (RF) ablation. However, no studies evaluate RMN-guided ablative therapy outcomes in children with VA yet. This study aimed to compare procedural and long-term outcomes between RMN-guided and manual (MAN)-guided VA ablation in children. This single-center, retrospective study included all CA procedures for VA performed in children with or without structural heart disease from 2008 until 2020. Two study groups were defined by CA technique: RMN or MAN. Primary outcome was recurrence of VA. Baseline clinical, procedural and safety data were also evaluated. This study included 22 patients, who underwent 30 procedures, with a median age of 15 (IQR 14–17; range 1–17) years and a mean weight of 57 ± 20 kg. In total, 14 procedures were performed using RMN and 16 using MAN (22 first and 8 redo procedures). Regarding first procedures, recurrence rates were significantly lower in RMN compared to MAN (20% versus 67%, P = 0.029), at a mean follow-up of 5.2 ± 3.0 years. Moreover, fluoroscopy dosages were significantly lower in RMN compared to MAN [20 (IQR 14–54) versus 48 (IQR 38–62) mGy, P = 0.043]. In total, 20 patients (91%) were free of VA following their final ablation procedure. This is the first study to investigate the use of RMN in pediatric VA ablation. RMN showed improved outcomes compared to MAN, resulting in lower VA recurrence and reduced fluoroscopy exposure.
Host-Associated Bacterial Communities Vary Between Daphnia galeata Genotypes but Not by Host Genetic Distance
Authors: Rajarajan Amruta , Wolinska Justyna , Walser Jean-Claude , Dennis Stuart R. , Spaak Piet 
Published: April 2022

Abstract
Host genotype may shape host-associated bacterial communities (commonly referred to as microbiomes). We sought to determine (a) whether bacterial communities vary among host genotypes in the water flea Daphnia galeata and (b) if this difference is driven by the genetic distance between host genotypes, by using D. galeata genotypes hatched from sediments of different time periods. We used 16S amplicon sequencing to profile the gut and body bacterial communities of eight D. galeata genotypes hatched from resting eggs; these were isolated from two distinct sediment layers (dating to 1989 and 2009) of a single sediment core of the lake Greifensee, and maintained in a common garden in laboratory cultures for 5 years. In general, bacterial community composition varied in both the Daphnia guts and bodies; but not between genotypes from different sediment layers. Specifically, genetic distances between host genotypes did not correlate with beta diversity of bacterial communities in Daphnia guts and bodies. Our results indicate that Daphnia bacterial community structure is to some extent determined by a host genetic component, but that genetic distances between hosts do not correlate with diverging bacterial communities.
Comparing the diagnostic performance of radiotracers in prostate cancer biochemical recurrence: a systematic review and meta-analysis
Authors: Ma Weili , Mao Jiwei , Yang Jianfeng , Wang Ting , Zhao Zhen Hua 
Published: April 2022

Abstract
Objectives
To systematically assess the early detection rate of biochemical prostate cancer recurrence using choline, fluciclovine, and PSMA.

Methods
Under the guidance of the Preferred Reporting Items for Systematic reviews and Meta-Analysis Diagnostic Test Accuracy guidelines, literature that assessed the detection rates (DRs) of choline, fluciclovine, and PSMA in prostate cancer biochemical recurrence was searched in PubMed and EMBASE databases for our systematic review from 2012 to July 15, 2021. In addition, the PSA-stratified performance of detection positivity was obtained to assess the DRs for various methods, including fluciclovine, PSMA, or choline PET/CT, with respect to biochemical recurrence based on different PSA levels.

Results
In total, 64 studies involving 11,173 patients met the inclusion criteria. Of the studies, 12, 7, and 48 focused on choline, fluciclovine, and PSMA, respectively. The pooled DRs were 24%, 37%, and 44%, respectively, for a PSA level less than 0.5 ng/mL (p < 0.001); 36%, 44%, and 60% for a PSA level of 0.5–0.99 ng/mL (p < 0.001); and 50%, 61%, and 80% for a PSA level of 1.0–1.99 ng/mL (p < 0.001). The DR with 18F-labeled PSMA was higher than that with 68Ga-labeled PSMA, and the DR was 58%, 72%, and 88% for PSA levels < 0.5 ng/mL, 0.5–0.9 ng/mL, and 1.0–1.99 ng/mL, respectively.

Conclusion
The DRs of PSMA-radiotracers were greater than those of choline-radiotracers and fluciclovine-radiotracers at the patient level. 18F-labeled PSMA achieved a higher DR than 68Ga-labeled PSMA.

Key Points
• The DRs of PSMA-radiotracers were greater than those of choline-radiotracers and fluciclovine-radiotracers at the patient level.
•18F-labeled PSMA achieved a higher DR than68Ga-labeled PSMA.
The Asymmetric Connection of SST in the Tasman Sea with Respect to the Opposite Phases of ENSO in Austral Summer
Authors: Sun Xueqian , Li Shuanglin , Liess Stefan 
Published: April 2022

AbstractThis study uses linear regression and composite analyses to identify a pronounced asymmetric connection of sea surface temperature (SST) in the Tasman Sea with the two opposite phases of El Niño-Southern Oscillation (ENSO) during austral summer. In El Niño years, the SST anomalies (SSTAs) in the Tasman Sea exhibit a dipolar pattern with weak warmth in the northwest and modest cooling in the southeast, while during La Niña years the SSTAs exhibit a basin-scale warmth with greater amplitude. Investigations into the underlying mechanism suggest that this asymmetry arises from a mechanism related to oceanic heat transport, specifically the anomalous Ekman meridional heat transport induced by the zonal wind stress anomalies, rather than the surface heat fluxes on the air-sea interface. Further analysis reveals that the asymmetry of oceanic heat transport between El Niño and La Niña years is driven by the asymmetric atmospheric circulation over the Tasman Sea stimulated by the asymmetric diabatic heating in the tropical Pacific between the two opposite ENSO phases.
Impact of bariatric surgery on the effectiveness of serological response after COVID-19 vaccination
Authors: Hany Mohamed , Torensma Bart , Abouelnasr Anwar Ashraf , Zidan Ahmed , Ibrahim Mohamed , Agayby Ann Samy Shafiq , Hesham Mohamed , Elsheredy Amel , Abu-Sheasha Ghada Ahmed 
Published: April 2022

Abstract
Purpose
The primary objective of the current study is to determine whether bariatric surgery reversed the negative impact of obesity on the serological response after the COVID-19 vaccination. This objective is achieved in two steps: (a) quantifying the negative impact of obesity on the serological response after COVID-19 vaccination if it is present, and (b) testing whether bariatric surgery reversed this impact. The secondary objective was to monitor the occurrence of adverse events.

Methods
This is a prospective cohort study between May 2021 and August 2021 on the strength of serological response after COVID-19 vaccination. Patients were classified into three groups. Group A (controls with normal or overweight), Group B (bariatric patients pre-operative), and Group C (bariatric patients post-operative). Quantitative antibodies against SARS‑CoV‑2 RBD with a strong neutralizing capacity were quantified from sera after at least 2 weeks post-vaccination.

Results
Of the 276 participants, Group A had n = 73, Group B had n = 126, and Group C had n = 77 patients. Overall, a strongly positive vaccine serological response was observed among 86% in group A, 63% in Group B, and 88% in Group C. Group C showed 5.33 times [95% CI 2.15 to 13.18] higher immune response than group B. Mild to moderate adverse events occurred in 30.1% [95% CI 24.7 to 35.9] of the study samples. Adverse events with the whole virus, mRNA, and vector vaccines occurred in 25%, 28%, and 37%, respectively.

Conclusion
Vaccinating and bariatric surgery are safe and effective treatments in the serological response in patients who suffer from obesity.
Numerical analysis of the magnetic shape memory effect based on the absolute nodal coordinate formulation
Authors: Wang Tengfei , Nemov Alexander S. , Matikainen Marko K. , Mikkola Aki 
Published: April 2022

AbstractIn this paper, the absolute nodal coordinate formulation (ANCF) is applied to simulate the magnetic shape memory effect. Using the absolute nodal coordinate formulation makes it possible to describe complicated or large deformation cases. The nonlinear bidirectional coupling terms between the mechanical and magnetic field are taken into account in the analysis of the single-crystalline Ni-Mn-Ga sample. A two-loop iteration procedure with variable steps is implemented to predict the magnetic-field-induced strain (MFIS) in the specimen under a changing external magnetic field and a constant auxiliary compression. In addition, the proposed approach is used to track the superelastic behavior of the magnetic shape memory alloy when subjected to a constant magnetic field. The approach effectively describes the hysteresis and superelastic phenomenon of the shape memory effect. The solution is compared here with solutions obtained using classical linear and quadratic quadrilateral elements. The deviation observed in the solution is discussed, and its cause is further clarified from a two-domain pure magnetostatic analysis of a permanent magnet. It is found that the accurate solution of such problems is associated with discontinuity of the normal component of the magnetic potential gradient across the domain interface. Special measures must be taken to make the absolute nodal coordinate formulation element compatible with the discontinuity. A mixed FEs strategy, which adopts ANCF FE in the displacement field solver and classical FE in the magnetic field solver, is proposed as an alternative option to rectify the problem, which is verified by predicting the MFIS and the dynamic mechanical response of a sample under cyclic compression.
Mixed finite elements applied to acoustic wave problems in compressible viscous fluids under piezoelectric actuation
Authors: Meindlhumer Martin , Pechstein Astrid , Jakoby Bernhard 
Published: April 2022

AbstractIn the present contribution, we develop a mixed finite element method capable of the coupled multi-field simulation of a viscous fluid actuated by a piezoelectric resonator. Several challenges are met with in this setting, among which are the necessity of correct interface coupling, near incompressibility of the fluid, adverse geometric dimensions of flat piezoelectric transducers and different length scales of shear and pressure wave. Assuming small deformations and velocities, we present a mixed variational formulation with consistent interface coupling conditions in (mechanic) frequency domain. Both fluid and piezoelectric solid domain are discretized using Tangential-Displacement Normal-Normal-Stress elements. These elements model not only the deformation, but add an independent tensor-valued stress approximation. The method has been rigorously proven to be free from shear locking for flat prismatic or hexahedral elements. Thus, modeling of the flat geometry of piezoelectric resonators as well as resolution of the fastly decaying shear wave are facilitated. To circumvent the problem of volume locking due to the near incompressibility of the fluid, an additional independent pressure field is introduced. We present computational results indicating the capability of the method.
The full story of 1000 cores
Authors: Bang Tiemo , May Norman , Petrov Ilia , Binnig Carsten 
Published: April 2022

AbstractIn our initial DaMoN paper, we set out the goal to revisit the results of “Starring into the Abyss [...] of Concurrency Control with [1000] Cores” (Yu in Proc. VLDB Endow 8: 209-220, 2014). Against their assumption, today we do not see single-socket CPUs with 1000 cores. Instead, multi-socket hardware is prevalent today and in fact offers over 1000 cores. Hence, we evaluated concurrency control (CC) schemes on a real (Intel-based) multi-socket platform. To our surprise, we made interesting findings opposing results of the original analysis that we discussed in our initial DaMoN paper. In this paper, we further broaden our analysis, detailing the effect of hardware and workload characteristics via additional real hardware platforms (IBM Power8 and 9) and the full TPC-C transaction mix. Among others, we identified clear connections between the performance of the CC schemes and hardware characteristics, especially concerning NUMA and CPU cache. Overall, we conclude that no CC scheme can efficiently make use of large multi-socket hardware in a robust manner and suggest several directions on how CC schemes and overall OLTP DBMS should evolve in future.
Impact of sports on temporomandibular dysfunction: a comparison of competitive and recreational female athletes as well as female non-athletes
Authors: Freiwald Hannah Charlotte , Schwarzbach Nico Peter , Wolowski Anne 
Published: April 2022

Abstract

Objectives
The present study was conducted to investigate the correlation between (competitive) sports and the occurrence of temporomandibular dysfunctions (TMD) by comparing the prevalences in competitive, recreational, and non-athletic women.

Materials and methods
A total of 138 women between the ages of 18 and 45 were interviewed about symptoms of TMD by means of a questionnaire. Based on their athletic performance level, the participating women were classified as competitive athletes, recreational athletes, or non-athletes (each group n = 46).

Results
Symptoms of TMD were notably less frequent in competitive female athletes (52.2%) than in recreational female athletes (63.0%) and female non-athletes (60.9%). With increasing training load, the prevalence of TMD decreased in both the competitive and recreational female athlete groups.

Conclusions
Athletic activity in general seems to have a positive effect on the occurrence of TMD. Competitive female athletes appear less likely to suffer from symptoms of TMD than recreational athletes and non-athletes. One possible explanation for this could be the better supervision by qualified trainers and physiotherapists in competitive sports.

Clinical relevance
Patients should be motivated to engage in sports as a protective measure against symptoms of TMD. However, it is important to ensure that they are properly instructed by experienced personnel in order to avoid unphysiological strain and negative consequences.
Influence on the patient’s oral hygiene depending on the treatment performed by either one or different pre-graduate practitioners — a randomized, controlled, clinical short-term trial
Authors: Herz Marco M. , Celebi Nora , Bruckner Thomas , Bartha Valentin 
Published: April 2022

Abstract
Objectives
Plaque control by improved domestic oral hygiene is essential in periodontal treatment. However, changing treatment providers may interfere with building a dentist-patient relationship and in turn affect treatment success. The aim of this randomized, controlled, prospective short-term study was to determine the influence of either one or four different pre-graduate practitioners on patients’ oral hygiene parameters during active periodontal therapy.

Material and Methods
A total of 55 patients with periodontitis were allocated to two groups. Within the group “continuous treatment” (CT, n = 27), each patient was treated by one individual practitioner over the treatment period. For patients of the group “discontinuous treatment” (DT, n = 28), treatment in each session was performed by a different practitioner. Periodontal parameters (BOP, PBI, and PCR) were assessed at two timepoints: T1 (baseline) and T2 (end of active therapy).

Results
With CT, the PBI improved in 93% of the patients, compared to 71% with DT (p = 0.048). T1-T2 intragroup analysis showed a statistically significant improvement of all observed clinical parameters with no differences in ∆PBI, ∆BOP, and ∆PCR. Spearman’s correlation analysis revealed a weak correlation between PCR and BOP of CT only.

Conclusions
In the present study, improvement of all parameters was comparable between the groups. PBI, as a parameter displaying patient’s domestic plaque control compliance, improved in more patients from CT than DT. This is possibly indicating an advantage of continuous treatment by one single practitioner.

Clinical relevance
Treatment by either a single practitioner or by multiple, constantly changing practitioners might influence patients’ compliance to modify their behaviour when medically necessary.
Screening of microRNA and mRNA related to secondary hair follicle morphogenesis and development and functional analysis in cashmere goats
Authors: Shang Fangzheng , Wang Yu , Ma Rong , Rong Youjun , Wang Min , Wu Zhihong , Hai Erhan , Pan Jianfeng , Liang Lili , Wang Zhiying , Wang Ruijun , Su Rui , Liu Zhihong , Zhao Yanhong , Wang Zhixin , Li Jinquan , Zhang Yanjun 
Published: April 2022

Abstract
microRNA (miRNA) is a type of endogenous short-chain non-coding RNA with regulatory function found in eukaryotes, which is involved in the regulation of a variety of cellular and biological processes. However, the research on the development of cashmere goat secondary hair follicles is still relatively scarce. In this study, small RNA libraries and mRNA libraries of 45 days, 55 days, 65 days, and 75 days of fetal skin of cashmere goats were constructed, and the constructed libraries were sequenced using Illumina Hiseq4000, and the expression profiles of miRNA and mRNA in cashmere goat fetal skin were obtained. The differentially expressed miRNAs and mRNAs in six control groups were identified and the qRT-PCR experiment shows that the sequencing results are accurate. Sixty-six miRNAs related to secondary hair follicle development were screened, and used TargetScan and miRanda to predict 33 highly expressed miRNA target genes. At the same time, 664 mRNAs related to the development of secondary hair follicles were screened, and GO enrichment and KEGG pathway analysis were performed. It was found that some miRNA target genes were consistent with the screening results of mRNAs related to secondary hair follicle development and were enriched in Notch signaling pathway, TGF-β signaling pathway. Therefore, miR-145-5p-DLL4, miR-27b-3p-DLL4, miR-30e-5p-DLL4, miR-193b-3p-TGF-β1, miR-181b-5p-NOTCH2, and miR-103-3p-NOTCH2 regulatory network related to the development of secondary hair follicles were constructed and the results of dual-luciferase reporter gene assay indicated that there is a targeted relationship between chi-miR-30e-5p and DLL4, which will provide a basis for molecular mechanism of miRNA-mRNA in the development of the hair follicles in cashmere goats.
Principal Components Along Quiver Representations
Authors: Seigal Anna , Harrington Heather A. , Nanda Vidit 
Published: April 2022

AbstractQuiver representations arise naturally in many areas across mathematics. Here we describe an algorithm for calculating the vector space of sections, or compatible assignments of vectors to vertices, of any finite-dimensional representation of a finite quiver. Consequently, we are able to define and compute principal components with respect to quiver representations. These principal components are solutions to constrained optimisation problems defined over the space of sections and are eigenvectors of an associated matrix pencil.
Introduction pathways of economically costly invasive alien species
Authors: Turbelin Anna J. , Diagne Christophe , Hudgins Emma J. , Moodley Desika , Kourantidou Melina , Novoa Ana , Haubrock Philip J. , Bernery Camille , Gozlan Rodolphe E. , Francis Robert A. , Courchamp Franck 
Published: April 2022

AbstractIntroduction pathways play a pivotal role in the success of Invasive Alien Species (IAS)—the subset of alien species that have a negative environmental and/or socio-economic impact. Pathways refer to the fundamental processes that leads to the introduction of a species from one geographical location to another—marking the beginning of all alien species invasions. Increased knowledge of pathways is essential to help reduce the number of introductions and impacts of IAS and ultimately improve their management.Here we use theInvaCostdatabase, a comprehensive repository on the global monetary impacts of IAS, combined with pathway data classified using the Convention on Biological Diversity (CBD) hierarchical classification and compiled from CABI Invasive Species Compendium, the Global Invasive Species Database (GISD) and the published literature to address five key points. Data were available for 478 individual IAS. For these, we found that both the total and annual average cost per species introduced through the ‘Stowaway’ (US$144.9bn; US$89.4m) and ‘Contaminant’ pathways (US$99.3bn; US$158.0m) were higher than species introduced primarily through the ‘Escape’ (US$87.4bn; US$25.4m) and ‘Release’ pathways (US$64.2bn; US$16.4m). Second, the recorded costs (both total and average) of species introduced unintentionally was higher than that from species introduced intentionally. Third, insects and mammals, respectively, accounted for the greatest proportion of the total cost of species introduced unintentionally and intentionally respectively, at least of the available records; ‘Stowaway’ had the highest recorded costs in Asia, Central America, North America and Diverse/Unspecified regions. Fourthly, the total cost of a species in a given location is not related to the year of first record of introduction, but time gaps might blur the true pattern. Finally, the total and average cost of IAS were not related to their number of introduction pathways. Although our findings are directly limited by the available data, they provide important material which can contribute to pathway priority measures, notably by complementing studies on pathways associated with ecologically harmful IAS. They also highlight the crucial need to fill the remaining data gaps—something that will be critical in prioritising limited management budgets to combat the current acceleration of species invasions.
Comparison of continuity equation and Gaussian mixture model for long-term density propagation using semi-analytical methods
Authors: Sun Pan , Colombo Camilla , Trisolini Mirko , Li Shuang 
Published: April 2022

AbstractThis paper compares the continuum evolution for density equation modelling and the Gaussian mixture model on the 2D phase space long-term density propagation problem in the context of high-altitude and high area-to-mass ratio satellite long-term propagation. The density evolution equation, a pure numerical and pointwise method for the density propagation, is formulated under the influence of solar radiation pressure and Earth’s oblateness using semi-analytical methods. Different from the density evolution equation and Monte Carlo techniques, for the Gaussian mixture model, the analytical calculation of the density is accessible from the first two statistical moments (i.e. the mean and the covariance matrix) corresponding to each sub-Gaussian distribution for an initial Gaussian density distribution. An insight is given into the phase space long-term density propagation problem subject to nonlinear dynamics. The efficiency and validity of the density propagation are demonstrated and compared between the density evolution equation and the Gaussian mixture model with respect to standard Monte Carlo techniques.