bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Modal Kerja Kas, Persediaan dan Hutang terhadap Pencapaian Laba pada Daffa Mart di Kabupaten Sorong
Authors: Anggraini Esi , Bintari Wisang Candra , Waly Nur Aeni 
Published: October 2022

Penelitian ini bertujuan untuk menganalisis pengaruh modal kerja kas, persediaan dan hutang terhadap pencapaian laba pada Daffa Mart di Kabupaten Sorong. Sampel yang digunakan dalam penelitian ini adalah 12 bulan berupa data keuangan dari bulan Januari 2021-Desember 2021. Metode analisis data yang digunakan dalam penelitian ini yaitu regresi linear berganda dengan bantuan Spss 20. Hasil dari penelitian ini menunjukkan bahwa kas tidak berpengaruh terhadap pencapaian laba, persediaaan berpengaruh terhadap pencapaian laba, dan hutang tidak berpengaruh terhadap pencapaian laba. Berdasarkan hasil penelitian dapat disimpulkan sebagai berikut: (1) Berdasarkan hasil secara simultan menunjukkan bahwa adanya pengaruh signifikan antara variabel kas (X1), persediaan (X2), dan hutang (X3) terhadap pencapaian laba (Y) pada Daffa Mart di Kabupaten Sorong. (2) Berdasarkan hasil secara parsial kas tidak berpengaruh terhadap pencapaian laba pada Daffa Mart. Hal ini ini menunjukkan bahwa semakin tinggi kas yang dimiliki perusahaan tidak selalu menunjukkan keadaaan perusahaan baik dan akan menyababkan adanya kas yang menganggur sehingga tidak maksimalnya penggunaan modal kerja dalam pencapaian laba. (2) Berdasarkan hasil secara parsial persediaan berpengaruh terhadap pencapaian laba pada Daffa Mart. Hal ini menunjukkan bahwa semakin Semakin rendahnya biaya yang harus dikeluarkan, maka laba perusahaan akan semakin naik. (3) Berdasarkan hasil secara parsial persediaan berpengaruh terhadap pencapaian laba pada Daffa Mart. Hal ini menunjukkan bahwa semakin Semakin rendahnya biaya yang harus dikeluarkan, maka laba perusahaan akan semakin naik. (4) Berdasarkan hasil secara parsial hutang tidak berpengaruh terhadap pencapaian laba pada Daffa Mart. Hal ini menunjukkan bahwa peningkatan hutang yang tidak diiringi dengan peningkatan laba.
Estudio de las causas del colapso de puentes en Ecuador (2000-2022).
Authors: Marín Guzmán Christopher Rodolfo , Maldonado Noboa Juan Sebastián 
Published: October 2022

En este artículo se estudiaron 72 casos de fallas de puentes en Ecuador reportadas desde el año 2000 hasta 2022. Para identificar las principales causas del colapso parcial o total de los puentes en estudio, se realizó un análisis y evaluación del daño de la estructura, mediante información divulgada públicamente. El 47% de los casos estudiados corresponde a puentes de hormigón, el 40% corresponde a estructuras de acero y el 13% restante comprenden puentes de madera. Las causas más frecuentes de fallas de puentes se atribuyeron a crecientes de ríos, sobrecargas e impactos. Las inundaciones y la socavación, contribuyeron al pico de frecuencia de fallas con un 46% de todas las fallas. La sobrecarga del puente y las fuerzas de impacto lateral de camiones y barcos constituyen el 25% de las fallas totales. Otras causas principales frecuentes son el diseño, los detalles, la construcción, el mantenimiento y eventos sísmicos. Basados en los resultados obtenidos, se evidencia la necesidad que tiene el país y la región en el área de conservación de las obras de Infraestructura vial. Por lo tanto, se recomienda crear un programa riguroso de administración, control y mantenimiento de los puentes en el país para evitar que se sigan presentando este tipo de desastres en el futuro.
The effect of job strain and worksite social support on reported adverse reactions of COVID-19 vaccine: A prospective study of employees in Japan
Authors: Sasaki Natsu , Kuroda Reiko , Tsuno Kanami , Imamura Kotaro , Kawakami Norito 
Published: October 2022

Abstract

Objectives
This prospective study aimed to examine the association of psychosocial working conditions with adverse reactions after receiving COVID-19 vaccination in a sample of employees in Japan.

Methods
The data were retrieved from an online panel of full-time employees (E-COCO-J). The analysis included participants who were employed and were not vaccinated at baseline (June 2021) but received vaccination at a 4-month follow-up (October 2021). An 11-item scale measured the adverse reactions. Four types of psychosocial working conditions (i.e., job demands, job control, and supervisor and coworker support) were measured using the Brief Job Stress Questionnaire. Multiple linear regression analyses were conducted to examine the relationship between the psychosocial working conditions and adverse reactions of COVID-19 vaccines, adjusting for socioeconomic variables, chronic disease, the number of vaccination, type of vaccine, anxiety for adverse reactions, fear and worry about COVID-19, and psychological distress at baseline.

Results
Overall, 747 employees were included in the analysis. The average number of adverse reactions was 3.8 (standard deviation = 2.2): Arm pain (81.1%), fatigues (64.1%), muscle pains (63.3%), and fever (37.5°C+) (53.5%) were reported more frequently. Coworker support score was significantly and negatively associated with the numbers of adverse reactions (standardized β = −0.100, P = .023). Women, young age, second-time vaccination, Moderna, and high psychological distress were significantly associated with adverse reactions.

Conclusions
Employees with low coworker support may be more likely to have adverse reactions after vaccinations. The findings of this study could support that increasing workplace support may reduce adverse reactions.
In Situ Nucleation‐Decoupled and Site‐Specific Incorporation of Å‐Scale Pores in Graphene Via Epoxidation
Authors: Huang Shiqi , Villalobos Luis Francisco , Li Shaoxian , Vahdat Mohammad Tohidi , Chi Heng‐Yu , Hsu Kuang‐Jung , Bondaz Luc , Boureau Victor , Marzari Nicola , Agrawal Kumar Varoon 
Published: October 2022

AbstractGenerating pores in graphene by decoupled nucleation and expansion is desired to achieve a fine control over the porosity, and is desired to advance several applications. Herein, epoxidation is introduced, which is the formation of nanosized epoxy clusters on the graphitic lattice as nucleation sites without forming pores. In situ gasification of clusters inside a transmission electron microscope shows that pores are generated precisely at the site of the clusters by surpassing an energy barrier of 1.3 eV. Binding energy predictions using ab initio calculations combined with the cluster nucleation theory reveal the structure of the epoxy clusters and indicate that the critical cluster is an epoxy dimer. Finally, it is shown that the cluster gasification can be manipulated to form Å‐scale pores which then effectively sieve gas molecules based on their size. This decoupled cluster nucleation and pore formation will likely pave the way for an independent control of pore size and density.
Extremely Suppressed Energetic Disorder in a Chemically Doped Conjugated Polymer
Authors: Kim Seong Hyeon , Yook Hyunwoo , Sung Woong , Choi Jinhyeok , Lim Hyungsub , Chung Sein , Han Jeong Woo , Cho Kilwon 
Published: October 2022

AbstractChemical doping can be used to tune the optoelectronic properties of conjugated polymers (CPs), extending their applications as conducting materials. Unfortunately, chemically doped CP films containing excess dopants exhibit an increase in energetic disorder upon structural alteration, and Coulomb interactions between charge carriers and dopants also affect such disorder. The increase in energetic disorder leads to a broadening of the density of states, which consequently impedes efficient charge transport in chemically doped CPs. However, the molecular origins that are inherently resistant to such incidental increase of energetic disorder in chemically doped CPs have not been sufficiently explored. Here, it is discovered that energetic disorder in chemically doped CPs can be suppressed to a level close to the theoretical limit. Indacenodithiophene‐co‐benzothiadiazole (IDTBT) doped with triethyloxonium hexachloroantimonate (OA) exhibits disorder‐free charge‐transport characteristics and band‐like transport behavior with astonishing carrier mobility as a result of reinforced 1D intramolecular transport. Molecular structure of IDTBT provides a capability to lower the energetic disorder that generally arises from the inclusion of heterogeneous dopants. The results suggest the possibilities of implementing disorder‐free CPs that exhibit excellent charge transport characteristics in the chemically doped state and satisfy a prerequisite for their availability in the industry.
Accelerating Electron‐Transfer Dynamics by TiO2‐Immobilized Reversible Single‐Atom Copper for Enhanced Artificial Photosynthesis of Urea
Authors: Li Dong , Zhao Yunxuan , Miao Yingxuan , Zhou Chao , Zhang Li‐Ping , Wu Li‐Zhu , Zhang Tierui 
Published: October 2022

AbstractPhotocatalysis as a sustainable technology is expected to provide a novel sight for the green synthesis of urea directly using N2, CO2, and H2O under mild conditions. However, the fundamental issue of inefficient electron transfer in photocatalysis strongly hinders its feasibility, especially for the above multi‐electron‐demanding urea synthesis. Herein, an effective strategy of accelerating electron‐transfer dynamics is reported by TiO2‐immobilized reversible single‐atom copper (denoted as Cu SA‐TiO2) to enhance the performance for photosynthesis of urea from N2, CO2, and H2O. As revealed by a series of quasi‐in‐situ characterizations (e.g., electron paramagnetic resonance, and wavelength‐resolved and femtosecond time‐resolved spectroscopies), the expedited dynamics behaviors originating from reversible single‐atom copper in as‐designed Cu SA‐TiO2 (electron extraction rate: over 30 times faster than the reference photocatalysts) allow the assurance of abundant and continual photogenerated electrons for multi‐electron‐demanding co‐photoactivation of N2 and CO2, resulting in considerable rates of urea production. The strategy above for improving the photoelectron‐extraction ability of photocatalysts will offer a high‐efficiency and promising route for artificial urea photosynthesis and other multi‐electron‐demanding photocatalytic reactions.
Regulation of Polymer Configurations Enables Green Solvent‐Processed Large‐Area Binary All‐Polymer Solar Cells With Breakthrough Performance and High Efficiency Stretchability Factor
Authors: Liu Jiabin , Deng Jiawei , Zhu Yangyang , Geng Xiaokang , Zhang Lifu , Jeong Sang Young , Zhou Dan , Woo Han Young , Chen Dong , Wu Feiyan , Chen Lie 
Published: October 2022

AbstractWith the great potential of the all‐polymer solar cells for large‐area wearable devices, both large‐area device efficiency and mechanical flexibility are very critical but attract limited attention. In this work, from the perspective of the polymer configurations, two types of terpolymer acceptors PYTX‐A and PYTX‐B (X = Cl or H) are developed. The configuration difference caused by the replacement of non‐conjugated units results in distinct photovoltaic performance and mechanical flexibility. Benefiting from a good match between the intrinsically slow film‐forming of the active materials and the technically slow film‐forming of the blade‐coating process, the toluene‐processed large‐area (1.21 cm2) binary device achieves a record efficiency of 14.70%. More importantly, a new parameter of efficiency stretchability factor (ESF) is proposed for the first time to comprehensively evaluate the overall device performance. PM6:PYTCl‐A and PM6:PYTCl‐B yield significantly higher ESF than PM6:PY‐IT. Further blending with non‐conjugated polymer donor PM6‐A, the best ESF of 3.12% is achieved for PM6‐A:PYTCl‐A, which is among the highest comprehensive performances.
Controllable Gold Nanocluster–Emulsion Interface for Direct Cell Penetration and Photothermal Killing
Authors: Yang Ning , Kang Yuetong , Cong Yujie , Wang Xiaoyu , Yao Chuang , Wang Shu , Li Lidong 
Published: October 2022

AbstractIn the view of their ability to be uptaken by cells, colloidal particles can exert diverse physiological effects and are promising vehicles for the intracellular delivery of biologically active substances. Given that the modulation of biomaterial interfaces greatly facilitates the prediction and control of the corresponding cellular responses, the interfacial behavior of hydrophobic dye‐modified gold (Au) nanoclusters (Au NCs) is rationally designed to develop Au NC‐containing emulsions and control their biointerfacial interactions with cell membranes. The observed biological performance is indicative of a physical penetration mechanism. The amphiphilic Au NCs decrease the interfacial energy of two immiscible liquids and hinder droplet coalescence to facilitate the formation of emulsions thermodynamically stabilized by dipole–dipole and hydrophobic interactions. Moreover, the amphiphilic Au NCs are localized on the emulsion droplet surface and form segregated interfacial microdomains that adapt to the membrane structure and facilitate the traverse of the emulsions across the cell membrane via direct penetration. Fast penetration coupled with excellent photophysical performance endows the emulsions with multifluorescence tracing and efficient photothermal killing capabilities. The successful change of the interaction mode between NCs and biological objects and the provision of a universal formulation to modulate biointerfacial interactions are expected to inspire new bioapplications.
Blockade of Nuclear β‐Catenin Signaling via Direct Targeting of RanBP3 with NU2058 Induces Cell Senescence to Suppress Colorectal Tumorigenesis
Authors: Zheng Can‐Can , Liao Long , Liu Ya‐Ping , Yang Yan‐Ming , He Yan , Zhang Guo‐Geng , Li Shu‐Jun , Liu Ting , Xu Wen Wen , Li Bin 
Published: October 2022

AbstractColorectal cancer (CRC) is one of the most common malignant tumors in the world, with high prevalence and low 5‐year survival. Most of the CRC patients show excessive activation of the Wnt/β‐catenin pathway which is a vital target for CRC treatment. Based on multiple CRC cell lines with different nuclear expression of β‐catenin, NU2058 is identified from a small molecule library consisting of 280 bioactive compounds and found to selectively inhibit the proliferation of CRC cells with nuclear β‐catenin activation in vitro and in vivo. The translational significance of NU2058 alone or in combination with chemotherapeutic drugs oxaliplatin and irinotecan (SN38) in CRC is demonstrated in orthotopic tumor model and patient‐derived xenograft models. By integrating limited proteolysis‐small molecule mapping (LiP‐SMap) and mass spectrometry (MS), Ran‐binding protein 3 (RanBP3) is identified as the direct target of NU2058. The results show that RanBP3 is a tumor suppressor in CRC and is associated with patient survival. Mechanistically, NU2058 increases the interaction of RanBP3 and β‐catenin to promote nuclear export of β‐catenin, which further inhibits transcription of c‐Myc and cyclin D1 to induce cell senescence. Collectively, NU2058 may serve as a promising therapeutic agent for CRC patients with selective disruption of pathologic Wnt/β‐catenin signaling.
A novel IL/MOF nanocomposite tailored for trace SO2 efficient capture based on synergistic effects
Authors: Zhao Huifang , Gu Xingping , Yan Tongan , Han Guopeng , Liu Dahuan 
Published: October 2022

AbstractDue to its toxicity and corrosiveness, it is of enormous significance to efficiently capture and recover sulfur dioxide (SO2) from flue gas and natural gas. Herein, a new type of IL/MIL‐0.7 composite was precisely designed to meet this challenge, which exhibits a high adsorption capacity for SO2 (13.17 mmol g−1) at 298 K and 1.0 bar while excludes almost completely carbon dioxide (CO2, 0.27 mmol g−1) and nitrogen (N2, 0.07 mmol g−1). The high IAST selectivity (at least 11,925) of IL/MIL‐0.7 for SO2/CO2 can be achieved within the whole test pressure range. In addition, the breakthrough experiment also confirmed the excellent performance of the composite for deep removal of 2000 ppm SO2. Furthermore, the IL/MIL‐0.7 composites can maintain excellent performance after four adsorption/desorption cycles and the thermostability can up to ~450 K. Therefore, this stable IL/MOF composite has the potential application as an effective adsorbent for SO2 removal from flue gas and natural gas.
A case with cardiac, skeletal, speech, and motor traits narrows the subtelomeric 19p13.3 microdeletion region to 46 kb
Authors: Peter Beate 
Published: October 2022

AbstractSubtelomeric 19p13.3 deletions have been associated with diverse anatomical and developmental phenotypes. A recent study of eight patients with subtelomeric interstitial 19p13.3 microdeletions at 0.3–1.4 Mb (hg 19) showed associations with growth restrictions, skeletal deformities, craniofacial anomalies, congenital heart defects, renal malformations, hernias, immune system deficits, fine and gross motor delays, speech delays, and developmental and learning delays. The authors defined two small regions of overlap containing four and 11 genes, respectively, with potential haploinsufficiency. Here, we present a new case with a de novo 184 kb deletion containing eight genes, three of which fall into the second previously identified small region of overlap, reducing the shared region to 46 kb. Phenotypic traits include most of the core findings in the previously reported cases but not growth restrictions, craniofacial anomalies, renal malformation, and learning disability. A closer look at the speech and motor delays reveals apraxic speech and discoordination in the fine and gross motor domain, consistent with cerebellar involvement across motor systems. Findings are consistent with a role of AZU1 in the observed immune deficiencies and PTBP1 in the observed skeletal, abdominal, speech, language, motor, and sensory traits. This case thus contributes to a more nuanced understanding of the subtelomeric 19p13.3 deletion region.
Dynamic Covalent Michael Acceptors to Penetrate Cells: Thiol‐Mediated Uptake with Tetrel‐Centered Exchange Cascades, Assisted by Halogen‐Bonding Switches
Authors: Shybeka Inga , Maynard John R. J. , Saidjalolov Saidbakhrom , Moreau Dimitri , Sakai Naomi , Matile Stefan 
Published: October 2022

AbstractChalcogen‐centered cascade exchange chemistry is increasingly understood to account for thiol‐mediated uptake, that is, the ability of reversibly thiol‐reactive agents to penetrate cells. Here, reversible Michael acceptors are shown to enable and inhibit thiol‐mediated uptake, including the cytosolic delivery of proteins. Dynamic cyano‐cinnamate dimers rival the best chalcogen‐centered inhibitors. Patterns generated in inhibition heatmaps reveal contributions from halogen‐bonding switches that occur independent from the thyroid transporter MCT8. The uniqueness of these patterns supports that the entry of tetrel‐centered exchangers into cells differs from chalcogen‐centered systems. These results expand the chemical space of thiol‐mediated uptake and support the existence of a universal exchange network to bring matter into cells, abiding to be decoded for drug delivery and drug discovery in the broadest sense.
Assessment of mechanical and healing behaviors of glass fibers‐epoxy composite containing the microcapsules with the nanocomposite shell
Authors: Ebrahimnezhad‐Khaljiri Hossein , Eslami‐Farsani Reza , Mirzamohammadi Sadegh 
Published: October 2022

AbstractIn the current study, the effect of adding the encapsulated healing agent with neat polymeric and nanocomposite shells on the mechanical‐healing features of glass fibers/epoxy composite under various loads was investigated. Therefore, the microcapsules with urea‐formaldehyde (UF) nanocomposite shell containing the various weight fraction of silica nanoparticles (0, 1, 2, 3) were synthesized. After that, the flexural, tensile, and interlaminar shear strength (ILSS) samples were destructed by using the quasi‐static penetration method with the damaging force of 500, 1050, and 2900 N, respectively. The maximum healing efficiency in the flexural loads belonged to the composite with the 3 wt% nanosilica on the surface of microcapsules, which was 83.9%. Also, it was found the increment in the weight fraction of silica nanoparticles had a negligible effect on the healing ability of composite under tensile loading. Achieving 135.8% healing efficiency in the composite with the 2 wt% nanosilica under the shear loads can be one of the most important findings in this work.
New data on the cranial anatomy ofPterogonaspis(Tridensaspidae, Galeaspida) from the lower Devonian of Yunnan, China and its evolutionary implications
Authors: Meng Xin‐Yuan , Zhu Min , Li Qiang , Gai Zhi‐Kun 
Published: October 2022

AbstractNew material of the tridensaspidPterogonaspis yuhaiiis described from the Xujiachong Formation in Qujing City, Yunnan Province, revealing the morphology of the ventral side of the headshield for the first time. Most significantly, the cranial anatomy ofPterogonaspisprovides the first fossil evidence for the position of the esophagus in galeaspids. The esophagus and dorsal aortae display a central placement in the postbranchial region and do not share a common canal as in osteostracans. Moreover, the paired and symmetrically extending dorsal aortae in galeaspids strikingly resemble those of jawed vertebrates, probably representing a plesiomorphic condition for vertebrates because they are also present in amphioxus and hagfishes. In contrast, the unpaired and asymmetrically extending dorsal aorta in osteostracans is similar to that of lampreys, probably resulting from convergent evolution. In addition, our new data also exhibit some characters that galeaspids uniquely share with osteostracans, such as the complete endoskeletal postbranchial wall and the extensive lateral expansion of the headshield with the marginal arteries and veins.
Paleobiological inferences from paleopathological occurrences in the Arctic ceratopsian Pachyrhinosaurus perotorum
Authors: Fiorillo Anthony R. , Tykoski Ronald S. 
Published: October 2022

AbstractAs a key tool for understanding how animals lived in the past, paleopathology informs us about the lives and deaths of fossil animals. We identify paleopathologies within an assemblage of bones of the pachyrostran centrosaurine Pachyrhinosaurus perotorum, an Arctic ceratopsian. More than 1,000 bones of this dinosaur were collected from the Prince Creek Formation of North Slope, Alaska from fossil sites along the Colville River. Our survey shows the occurrence of paleopathology to be very low and comparable to other populations of horned dinosaurs from the lower latitudes, suggesting that the ancient Arctic environment did not impose intense hardships on these dinosaurs greater than in other environments, as expressed by paleopathological modification of the skeleton. This result may be due to the more equable mean annual temperatures in the Arctic region during the Cretaceous. Also of interest, the frequency of occurrence of paleopathology in the Arctic Pachyrhinosaurus population is very low compared to populations of fossil and historic quadrupedal artiodactyls that are recognized as long distance wanderers.
Ru‐, Rh‐ and Ir‐Catalyzed Enantioselective sp3C−H Functionalization
Authors: Kaur Ramandeep , Jain Nidhi 
Published: October 2022

AbstractThe development of novel methodologies that enable the construction of complex chiral molecular scaffolds in an atom and step‐economic manner has always been an area of immense interest and significant synthetic value. The transition metal‐catalyzed enantioselective sp3C−H activation and functionalization reactions serve as an expeditious means for introducing diverse functionalities in a straightforward manner. However, controlling the chemo‐ and stereoselectivity of these reactions is a significant challenge owing to their ubiquity and low reactivity. In this review, we present a comprehensive account on the recent advances in inter‐ and intramolecular asymmetric sp3C−H bond functionalization utilizing ruthenium, rhodium, and iridium catalysts and get insights into the mechanistic aspects of these transformations.