bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rare Alkali Metals in the Waters of Lithium-containing Deposits in Eastern Transbaikalia
Authors: Abramova V A 
Published: January 2022

Abstract
The results of hydrogeochemical studies on the content of rare alkaline elements in man-made waters of mining facilities at Zavitinskoye, Orlovskoye, and Etykinskoye rare metal deposits of Eastern Transbaikalia are presented. Concentrations of these elements are determined both by the content in the ores and rocks of deposits and by their water-migration properties. It was found that the acidic sub-basement waters of the Orlovskoye and the quarry waters of the Zavitinskoye deposits contain abnormally high concentrations of lithium, up to 3.74 and 3.88 mg / L, respectively. The high content of lithium (Li) in the waters of these deposits was determined relative to the average values for the waters of the hypergenesis zone, as well as the standards of maximum permissible concentrations (MPC) of chemicals for water bodies used for fisheries, drinking water, and other activities.
Climatic Change as a Driver of Economic Development: an Example from Angara–Yenisey Siberia
Authors: Gordeev R V , Pyzhev A I , Zander E V 
Published: January 2022

Abstract
Climate change and its impact on economic development is an important, but still understudied issue. This paper is aimed to fill in this gap in relation to the Angara–Yenisey macroeconomic region. It contributes to the literature in several dimensions. First, an overview of research on the climate impact on various sectors of the Russian economy is given. Second, we showed the main trends and factors in the dynamics of economic development in Russia over the past 20 years. And at last, the comparison of the average annual temperature and the gross regional product growth rates was conducted for the four regions of the Angara–Yenisey Siberia. It was concluded that there is no sufficient evidence that regional economies are significantly dependent on temperature fluctuations. Nevertheless, there is still space for further research.
The ecological and economic achievements in landscape optimization of technogenic reliefs
Authors: Gordin I V , Ryumina E V 
Published: January 2022

Abstract
Mining and accumulation of industrial and household waste on the earth’s surface form the technogenic relief of the planet. The main forms of violation of the natural relief are quarries, ditches, landfills and spoil tips. There are two ways of landscape optimization in order to restore ecological balance, to turn the aggressive terrain into an ecological and economic value. The first is a return to the original natural landscape. The process is implemented by ground filling of technogenic depressions, removal and chemical and technological processing of waste accumulated at landfills and spoil tips. The second way is to use technogenic relief to form a new natural landscape. The main attention of the article is paid to the optimization of technogenic landscapes by forest plantations and forest reclamation. As a result of these activities, environmentally safe and aesthetically expressive spaces are formed. Most of these facilities have a high potential for economic, socio-economic and recreational use. The outstanding world achievements in this field are considered. Their ecological and economic characteristics are given.
Adjustments to the economic assessment of environmental violations
Authors: Gordin I V , Ryumina E V 
Published: January 2022

Abstract
The article highlights a number of scientific and practical issues of methodology for assessing economic damage. Special attention is paid to the damage caused by environmental violations associated with the long-term accumulation of pollution in uncontrolled territories. A number of world and Russian examples of large-scale environmental violations that caused enormous economic damage are given. The necessity of deepening and correcting a number of points in the analysis of ecological-economic and ecological-legal problems of damage assessment is emphasized.
Priority social and economic development areas as an economic development tool for the Siberian mono-settlements
Authors: Gurova O 
Published: January 2022

Abstract
The article is discussing the Priority Social and Economic Development Areas (PSEDAs) which are formed in the Siberian part of the Russian Federation (Siberian Federal District and the Baikal region). One of the goals for the PSEDAs formation is the diversification of mono-specialized towns and the reduction of their reliance on the city-forming enterprises. A typology of mono-settlements was carried out and the areas of activity that receive support within the framework of this mechanism in Siberia were presented.
A method of measuring transmittance of radiation from the film of ice 0 in the IR wave band deposited on a dielectric plate
Authors: Orlov A O , Gurulev A A , Tsyrenzhapov S V 
Published: January 2022

Abstract
A method of measuring transmittance of radiation from the film of ice 0 in the infrared wave band is described. Ice 0 is formed from supercooled water at the temperature below –23°C. This ice is ferroelectric and forms a highly conductive layer of the nanometric order of thickness at the boundary with dielectric. The complexity of the experiment consisted in the necessity of using low intensities of the probing signal and considering radiation of the cooled parts of the installation. In order to obtain a thin film of ice, the method of depositing water vapor on a substrate cooled in nitrogen was used. The method rules out formation of condensate in cooling. Deposition of water vapor is possible only in heating, when delivery of cold nitrogen vapor into the chamber with the sample is excluded. To ensure exposure of the film to IR radiation, two sources of infrared radiation were considered: a halogen lamp with a broad radiation spectrum (on the surface of heated glass) and a CO2 laser with the radiation wavelength of 10.6 µm. In the first case, spectral measurements are possible when filters are used. In the installation based on a CO2 laser, an intense signal is emitted, requiring consideration of sample heating. Components of the installation have been elaborated and investigated, on which transmittance of radiation from the film of ice 0 is planned to be measured.
Discovering formation of ice 0 by low-frequency measurement data
Authors: Orlov A O , Tsyrenzhapov S V 
Published: January 2022

Abstract
In this work, low-frequency characteristics of wetted nanoporous silicate materials were measured, as well as the specimen’s own low-frequency electric fluctuations at the frequencies of 1…100 Hz. The measurements at low frequencies were conducted at different voltages of the probing signal. A capacity cell was used in making the measurements. In the experiments, at the temperatures below –25…–30 °C, non-linearity of the medium was discovered. The experiments on the study of the specimen’s own electric fluctuations at these temperatures revealed their essential increase. These temperatures are below the point of phase transition of supercooled water to recently discovered ferroelectric ice 0. Based on the measurements made, a conclusion was made regarding formation of this modification of ice in the nanosize pores of the wetted materials under study. Ice 0 is a ferroelectric; therefore, its formation from deeply supercooled water may have a significant impact on the electric parameters of wetted bodies at the temperatures below –23 °C. At the interface of such ice with another dielectric, a thin layer with practically metallic conductivity emerges. Such a layer influences not only the non-linear dependence of dielectric permittivity on the electric field but also increases attenuation of electromagnetic radiation in a medium.
Why young people leave the Arctic: the results of sociological research
Authors: Potravnaya E V , Tishkov S V 
Published: January 2022

Abstract
The article deals with the issues of technogenesis and the evolution of relations with the environment through the example of the industrial development of the Arctic. The economic, environmental, and social aspects of the behavior of the indigenous population, the migration sentiments of the young people in connection with the implementation of investment projects for the development of the territory are analyzed. Particular attention is paid to identifying the relationship between the migration processes and the industrial development of the Arctic, substantiating the participation of mining companies to improve the socio-economic development of the Russian Arctic, and promoting employment. The subject of the study are the economic and social relations, migration attitudes of the local population, and youth, which arise in the process of the industrial development of the territory in the Arctic. Based on the example of conducting sociological surveys of the local population in Taimyr, in the Arctic regions of Yakutia, Karelia, and the Murmansk Region, recommendations are formulated for managing migration processes, promoting employment, income growth, and socio-economic development of the territory within the framework of mining companies’ activities to implement investment projects for the industrial development of the Arctic.
The Innokenty Lopatin and Friedrich Schmidt 1866 Yenissei (‘Turukhansk’) expedition: the first evidence of discovery of Norilsk-Talnakh Cu-Ni-PGE deposits
Authors: Kurguzova A V , Morozov M V 
Published: January 2022

Abstract
The history of the the discovery of world’s largest Ni-Cu-PGM deposits of Norilsk-Talnakh is revised. The 1866 prospecting and geographic expedition of Innokenty Lopatin and Friedrich Schmidt, studied the lowest Yenissei territories, and collected information and mineralogical samples (chalcopyrite from ‘copper slates’) proving by this the presence of a copper ore deposit in the Norilsk mountains. The deposit was developed by at least two adits since 1865 and was managed by brothers Pyotr and Cyprian Sotnikov from the settlement of Dudino (now Dudinka). This information was documented in the diaries by I. Lopatin and was reported by F. Schmidt in transactions of the Saint Petersburg Academy of Sciences. After the ‘re-discovery’ of the deposit in the 20th century the followers have ignored, omitted and incorrectly cited the information published by Friedrich Schmidt in 1869 and 1872, as well as its republishing made by Vladimir Obrutchev in 1917. The real sequence of events resulting in the discovery of Norilsk deposits has to be rewritten.

In memoriam of Sergey Gorbunov (1952–2021), archaeologist, traveler, Sakhalin history specialist
Prospects and priorities for the reconstruction and development of lithium mining production on the basis of domestic raw materials
Authors: Melentiev G B , Yurgenson G A , Delitzyn L M 
Published: January 2022

Abstract
The prospects of lithium as a component of new energy are considered. Provides data on the resources of lithium mineral raw materials. Variants of the reconstruction of lithium production facilities in Russia from domestic raw materials are evaluated in order to solve the problem of import substitution. Attention is focused on the choice of objects of priority industrial development and the need to create modern technologies for processing lithium raw materials. It is shown that the restored Zabaikalsk mining and processing plant can be a reliable source of lithium when using new technological solutions for extracting lithium and associated useful components from primary ores and waste of spodumene ores.
Modern materialistic understanding of the “energy” notion and the method of its systemic evaluation in chemicals
Authors: Sirotkin O S , Sirotkin R O 
Published: January 2022

Abstract
It was shown that the traditional approaches to understanding the notion of “energy” as a work or a physical quantity are outdated. For example, R. Feynman noted that “today’s physics does not know what energy is.” Therefore, even now, some researchers believe that “by and large, the concept of energy… is artificial, because unlike matter, of which we can say that it exists, energy is the fruit of human thought.” In contrast to these ideas, the authors showed that energy, like matter, objectively exists in various forms (energy continuum), which differ in structure, and is able to perform different types of work, to determine the forms of interaction and movement of matter in various material systems (substances, material bodies and megamaterial systems). A new scientific foundation for systematization and quantitative evaluation of energy characteristics of chemical compounds was proposed. It is based on a comprehensive assessment of contribution of chemical compounds’ composition and chemical bond type in line with a chemical bond’s unified model and the “System of chemical bonds and compounds” (SCBC). As a result of using this basic scientific innovation, the symbiosis of Mendeleev’s periodic table of atoms (composition – property) and SCBC (composition - chemical bond and structure – property) was realized for the first time. The foundation was laid for creating a database on systemic digitalization and evaluation of energy stored in various chemicals (natural gas, coal, oil, peat, wood, etc.) and the most effective ways of extracting it from these.
Heat transfer for the boiling crisis in porous systems
Authors: Genbach A A , Beloev H I , Bondartsev D Yu , Genbach N A 
Published: January 2022

Abstract
In this paper we analized and investigated the heat exchange crisis of boiling in porous structures, applicable in thermal power plants. Then we describe the heat exchange processes mechanism and determined the ideal sizes and thicknesses of porous structures. The designed porous structures can be implemented in gas turbine’s nozzles and combustion chambers. From an environmental point of view, the consumption coolant liquid is reduced by ten times in comparison the standard flow system. It’s effectively to develop mesh structures to allow the extension of the critical loads and manage the surface border.
Corrigendum: Study of the Radiotherapy Treatment Margins in Prostate Cancer with Fuzzy Logic Model (2020 IOP Conf. Ser.: Mater Sci Eng.
798 012042
)
Authors: Patnaikuni S K , Saini S M , Chandola R M , Choudhary V 
Published: January 2022

Abstract
Please see Article PDF for corrigendum text.
Imaging lidar prototype with homography and deep learning ranging methods
Authors: Kim Sehyeon , Chen Zhaowei , Alisafaee Hossein 
Published: January 2022

Abstract
We report on developing a non-scanning laser-based imaging lidar system based on a diffractive optical element with potential applications in advanced driver assistance systems, autonomous vehicles, drone navigation, and mobile devices. Our proposed lidar utilizes image processing, homography, and deep learning. Our emphasis in the design approach is on the compactness and cost of the final system for it to be deployable both as standalone and complementary to existing lidar sensors, enabling fusion sensing in the applications. This work describes the basic elements of the proposed lidar system and presents two potential ranging mechanisms, along with their experimental results demonstrating the real-time performance of our first prototype.
Rotational head acceleration and traumatic brain injury in combat sports: a systematic review
Authors: Lota Kabir Singh , Malliaropoulos Nikos , Blach Wiesław , Kamitani Takeshi , Ikumi Akira , Korakakis Vasileios , Maffulli Nicola 
Published: January 2022

Abstract

Background
Traumatic brain injury (TBI) in combat sports is relatively common, and rotational acceleration (RA) is a strong biomechanical predictor of TBI. This review summarizes RA values generated from head impacts in combat sport and puts them in the context of present evidence regarding TBI thresholds.

Sources of data
PubMed, EMBASE, Web of Science, Cochrane Library and Scopus were searched from inception to 31st December 2021. Twenty-two studies presenting RA data from head impacts across boxing, taekwondo, judo, wrestling and MMA were included. The AXIS tool was used to assess the quality of studies.

Areas of agreement
RA was greater following direct head strikes compared to being thrown or taken down. RA from throws and takedowns was mostly below reported injury thresholds. Injury thresholds must not be used in the absence of clinical assessment when TBI is suspected. Athletes displaying signs or symptoms of TBI must be removed from play and medically evaluated immediately.

Areas of controversy
Methodological heterogeneity made it difficult to develop sport-specific conclusions. The role of headgear in certain striking sports remains contentious.

Growing points
RA can be used to suggest and assess the effect of safety changes in combat sports. Gradual loading of training activities based on RA may be considered when planning sessions. Governing bodies must continue to work to minimize RA generated from head impacts.

Areas timely for developing research
Prospective research collecting real-time RA data is required to further understanding of TBI in combat sports.
DYT6 mutated THAP1 is a cell type dependent regulator of the SP1 family
Authors: Cheng Fubo , Zheng Wenxu , Barbuti Peter Antony , Bonsi Paola , Liu Chang , Casadei Nicolas , Ponterio Giulia , Meringolo Maria , Admard Jakob , Dording Claire Marie , Yu-Taeger Libo , Nguyen Huu Phuc , Grundmann-Hauser Kathrin , Ott Thomas , Houlden Henry , Pisani Antonio , Krüger Rejko , Riess Olaf 
Published: January 2022

Abstract
DYT6 dystonia is caused by mutations in the transcription factor THAP1. THAP1 knock-out or knock-in mouse models revealed complex gene expression changes, which are potentially responsible for the pathogenesis of DYT6 dystonia. However, how THAP1 mutations lead to these gene expression alterations and whether the gene expression changes are also reflected in the brain of THAP1 patients are still unclear. In this study we used epigenetic and transcriptomic approaches combined with multiple model systems [THAP1 patients’ frontal cortex, THAP1 patients’ induced pluripotent stem cell (iPSC)-derived midbrain dopaminergic neurons, THAP1 heterozygous knock-out rat model, and THAP1 heterozygous knock-out SH-SY5Y cell lines] to uncover a novel function of THAP1 and the potential pathogenesis of DYT6 dystonia.
We observed that THAP1 targeted only a minority of differentially expressed genes caused by its mutation. THAP1 mutations lead to dysregulation of genes mainly through regulation of SP1 family members, SP1 and SP4, in a cell type dependent manner. Comparing global differentially expressed genes detected in THAP1 patients’ iPSC-derived midbrain dopaminergic neurons and THAP1 heterozygous knock-out rat striatum, we observed many common dysregulated genes and 61 of them were involved in dystonic syndrome-related pathways, like synaptic transmission, nervous system development, and locomotor behaviour. Further behavioural and electrophysiological studies confirmed the involvement of these pathways in THAP1 knock-out rats.
Taken together, our study characterized the function of THAP1 and contributes to the understanding of the pathogenesis of primary dystonia in humans and rats. As SP1 family members were dysregulated in some neurodegenerative diseases, our data may link THAP1 dystonia to multiple neurological diseases and may thus provide common treatment targets.
High False-Positive Rate of (1,3)-β-D-Glucan in Onco-Hematological Patients Receiving Immunoglobulins and Therapeutic Antibodies
Authors: Tschopp Jonathan , Brunel Anne Sophie , Spertini Olivier , Croxatto Anthony , Lamoth Frederic , Bochud Pierre Yves 
Published: January 2022

Abstract
Immunoglobulins and/or therapeutic antibody preparations are associated with a high rate of false-positive (1,3)-β-D-glucan (BDG) tests in onco-hematological patients routinely screened for fungal infections. The benefit of BDG monitoring shall be balanced against the risk of false-positive tests leading to unnecessary investigations and costs in this population.
Development and Validation of a Parsimonious Tuberculosis Gene Signature Using the digital NanoString nCounter Platform
Authors: Kaipilyawar Vaishnavi , Zhao Yue , Wang Xutao , Joseph Noyal M , Knudsen Selby , Prakash Babu Senbagavalli , Muthaiah Muthuraj , Hochberg Natasha S , Sarkar Sonali , Horsburgh Charles R , Ellner Jerrold J , Johnson W Evan , Salgame Padmini 
Published: January 2022

Abstract

Background
Blood-based biomarkers for diagnosing active tuberculosis (TB), monitoring treatment response, and predicting risk of progression to TB disease have been reported. However, validation of the biomarkers across multiple independent cohorts is scarce. A robust platform to validate TB biomarkers in different populations with clinical end points is essential to the development of a point-of-care clinical test. NanoString nCounter technology is an amplification-free digital detection platform that directly measures mRNA transcripts with high specificity. Here, we determined whether NanoString could serve as a platform for extensive validation of candidate TB biomarkers.

Methods
The NanoString platform was used for performance evaluation of existing TB gene signatures in a cohort in which signatures were previously evaluated on an RNA-seq dataset. A NanoString codeset that probes 107 genes comprising 12 TB signatures and 6 housekeeping genes (NS-TB107) was developed and applied to total RNA derived from whole blood samples of TB patients and individuals with latent TB infection (LTBI) from South India. The TBSignatureProfiler tool was used to score samples for each signature. An ensemble of machine learning algorithms was used to derive a parsimonious biomarker.

Results
Gene signatures present in NS-TB107 had statistically significant discriminative power for segregating TB from LTBI. Further analysis of the data yielded a NanoString 6-gene set (NANO6) that when tested on 10 published datasets was highly diagnostic for active TB.

Conclusions
The NanoString nCounter system provides a robust platform for validating existing TB biomarkers and deriving a parsimonious gene signature with enhanced diagnostic performance.
Nucleic Acid Point-of-Care Testing to Improve Diagnostic Preparedness
Authors: Jani Ilesh V , Peter Trevor F 
Published: January 2022

Abstract
Testing programs for severe acute respiratory syndrome coronavirus 2 have relied on high-throughput polymerase chain reaction laboratory tests and rapid antigen assays to meet diagnostic needs. Both technologies are essential; however, issues of cost, accessibility, manufacturing delays, and performance have limited their use in low-resource settings and contributed to the global inequity in coronavirus disease 2019 testing. Emerging low-cost, multidisease point-of-care nucleic acid tests may address these limitations and strengthen pandemic preparedness, especially within primary healthcare where most cases of disease first present. Widespread deployment of these novel technologies will also help close long-standing test access gaps for other diseases, including tuberculosis, human immunodeficiency virus, cervical cancer, viral hepatitis, and sexually transmitted infections. We propose a more optimized testing framework based on greater use of point-of-care nucleic acid tests together with rapid immunologic assays and high-throughput laboratory molecular tests to improve the diagnosis of priority endemic and epidemic diseases, as well as strengthen the overall delivery of primary healthcare services.