bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Relationship between C-Reactive Protein and COPD Patients
Authors: Bhuvaneshwar G. A. , Dayanandan . 
Published: January 2022

Chronic Obstructive Pulmonary Disease (COPD) is a common, preventable, and treatable chronic inflammatory respiratory disease that affects 210 million people globally. Due to inflammation the resultant IL6 increases the level of C-REACTIVE PROTEIN (CRP) from hepatocytes. This study was conducted to evaluate the association of C-Reactive Protein in COPD patients. The study also includes the key role of C-reactive protein (CRP) in assessing the acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD), which has proven to be more valuable. This was a prospective study conducted over a period of three months between February 2021 and April 2021 at the department of General Medicine in Saveetha Medical College Hospital, Chennai. In a study of 50 patients, 25 were patients with COPD and 25 were a control group of healthy people. High Sensitivity C-Reactive Protein (hs-CRP), blood gases, spirometry, Body Mass Index (BMI), 6 Minute Walk Distance (6MWD) and GOLD stage of severity were measured. The serum hs-CRP was then evaluated for any correlation with the predictors of outcomes of COPD subjects. hs-CRP levels were higher in patients with COPD than in healthy individuals (4.82 / 0.8 mgl). A correlation was found between hs-CRP and the following variables:
FEV1 (r = -0.813; p < 0.01), 6MWD (r = -0.876; p < 0.01), GOLD stage (r = 0.797; p < 0.01) and evaluated. This study revealed that there is certain increase in hs-CRP in COPD patients due to inflammation. It acts not only as an inflammatory diagnostic marker, but also plays a role as predictor for the outcome of the disease and reducing the mortality rate.
Case Report Postoperative Case of Explore Laparotomy for Ruptured Ectopic Pregnancy with Septicemia
Authors: Choudhary Minakshi , Sayyad Akhtaribano , Yelne Seema , Bhovare Sagar , Choudhary Deepesh , Khobragade Darshana , Umate Roshan 
Published: January 2022

Introduction: Ectopic pregnancy is a pregnancy problem when the embryo attaches itself outside the uterus. Signs and symptoms include abdominal pain and vaginal bleeding, but less than 50 percent of affected women have both. it happened. Excessive bleeding may lead to a rapid heartbeat, fainting, or panic attack. Without abnormalities, the fetus can no longer survive. Obstetricians and gynaecologists face various obstacles in dealing with Jehovah's Witnesses.
Main Symptoms and/or Important Clinical Findings: A 20-year-old man with a post-operative case of Explore Laparotomy For Ruptured Ectopic Pregnancy with pyosalpinx with septicemia underwent surgery on 14/02/2021 investigating Laparotomy under GA. His diagnostic ultrasonography was performed. Complete the blood test. She had not dropped down before 8 days she was a primigravida at 2 months of pregnancy and then had abdominal pain as she grew stronger over time.
The Main Diagnoses, Therapeutic Interventions, and Outcomes: A 20-year-old man with a post-operative case of Explore Laparotomy for Ruptured Ectopic Pregnancy with pyosalpinx withsepticemia, with a complaint of abdominal pain, Treatment began on the day he received V fluids, Antibiotics Injectable. Initiated, Zonac suppository PR consulted. TPR Charting treatment interventions, I / O Charting, abortion chart,
Nursing Perspectives: Laboratory techniques are urgently required. To limit the development of treatments to enhance the outcome.
Conclusion: Although it is not uncommon for an ectopic pregnancy to exceed the first trimester, it does occur occasionally. As a result, in any emergency, abdominal surgery during pregnancy, Today, early intervention saves lives and reduces morbidity, but ectopic pregnancy still kills 4 to 10% of pregnant women and results in a higher ectopic pregnancy rate following pregnancy.
Case Report on Carcinoma on Hard Palate
Authors: Wavare Sonali , Meshram Dharti , Bokade Kanchan , Wagh Pranali 
Published: January 2022

Background: The hard palate is a thin horizontal bony plate made up of two bones of the facial skeleton, located on the roof of the mouth. The bones are the palatine process of the maxilla and the horizontal plate of the palatine bone. The hard palate spans the alveolar arch formed by the alveolar process that holds the upper teeth (when these are developed). If cancer is detected early, the overall 5-year survival rate for all persons is 85 percent. If cancer has progressed to other tissues or organs, as well as regional lymph nodes, the overall 5-year survival rate is 67%.
Objective: Want to highlight the importance of primary prevention; education on risks of alcohol/tobacco use and oral hygiene. Secondary prevention; Early biopsy of any ulceration of the hard palate that does not regress with medical treatment. This would allow early diagnosis and minimal treatment with less morbidity and better survival chances.
Case Presentation: A male of 58 yrs. old came with Pain in the mouth, difficulty in breathing, difficulty in mastication, difficulty in deglutition, balm application, change in voice tooth exfoliation, lack of appetite. Aggravates on mastication, difficulty in deglutition for 2 months, burning sensation on the consumption of spicy food for 2 months change in voice, nasal discharge, loss of appetite, weight loss, tooth exfoliation in the upper front region of jaw, and balm application (2-3episodes, 15 days back). All necessary investigations were carried out such as X-ray, MRI, CT scan, a biopsy of the tissue sample, and diagnosed Carcinoma on the Hard Palate. Treatment of this patient received antiemetic, analgesic, antibiotic, vitamin supplementary.
Prognosis: After treatment, the patient shows great improvement.
Conclusion: The therapeutic management for malignant tumors of the hard palate is essentially surgical, with or without postoperative radiotherapy, discussed on a case-by-case basis. The survival rate depends on several factors, including early diagnosis, histological characteristics and appropriate management. When ca of the palate is detected primary, the management is very effective.
In-vitro Antioxidant Activity and Preliminary Phytochemical Analysis of Different Leaf Extracts of Hemionitis arifolia
Authors: Priya Rajendran Raja , Bhadusha N. , Manivannan Veramuthu , Gunasekaran Thanthoni 
Published: January 2022

Objective: To evaluate the preliminary phytochemical content and antioxidant potential of the hydroalcoholic leaf extracts of Hemionitis arifolia.
Methods: Total phenolic, flavonoid and alkaloid contents were evaluated using spectrophotometric methods. The free radical scavenging activity of the leaf hydroalcoholic extract were evaluated against DPPH+, ABTS+, Reducing power assay and nitric oxide assay were determined.
Results: The hydroalcoholic concentrate of H. arifolia uncovered the most elevated polyphenol content when contrasted and the other phytoconstituents. Absolute phenol content of the hydroalcoholic separate was observed to be 31.78%, flavonoid content is 1.02% and Alkaloid content is 30.40% individually. The Solvent concentrates showed huge cell reinforcement movement, with hydroalcoholic extract. ABTS Assay, DPPH assay, Reducing power assay and Nitric oxide assay where the Inhibition concentration were 667.75µg/ml, 734.25 µg/ml, 791.58 µg/ml and 899.67 µg/ml.
Conclusion: This study suggests that hydroalcoholic leaf extracts of H. arifolia could be a potential source of natural antioxidant and justifies its use in ethno-medicine.
Knowledge and Awareness about Obesity Complications in Pregnancy among Reproductive Women
Authors: MiSudharshan S. , Annejohncy . 
Published: January 2022

Background: obesity in general predisposes expected to various noncommunicable diseases but its awareness in regards to the complications posed by it in reproductive women is underseen.
Methods: cross sectional study using an structured questionnaire.
Goal: To access the knowledge and awareness about complications of obesity in pregnancy among reproductive women
Statistical Analysis Used: Data was entered in excel spreadsheet and analysed using SPSS version 16.
Results: Majority of the participants [129 (86%)] knew that obesity affects reproductive health causing problem problems like just gestational diabetes mellitus GDM [ 136 (90.6%)], difficulties during labour, higher Chance of Caesarean [91(60.6)] section, Increased risk for hypertension [120 (80%)] infertility [ 53 (35.3%)], during pregnancy. Almost all of them know That obesity can increase problems in pregnancy for both mother and for the baby. Majority of them we are not sure if obesity causes increased chance of Foetal malformations [75 (50.2%)] Increased bleeding after delivery [103 (68.8%)] Most of them don’t know that obesity can cause increased bleeding after delivery, stillbirth [125 (83.3%)], miscarriage [111(74%)], difficulties in Ultrasound examination of the abdomen [81 (54%) ]Most of them thought that obesity does not cause difficulties in measuring BP [79 (52.6)], delivery of big baby [98 (65.3%) ], premature delivery [56 (37.3%)].
Conclusion: Generating Awareness about obesity and its complications in pregnancy is required to prevent those complications in future and bring behavioural and lifestyle modification for sustainability in the long run.
Prevalence of Depression in Medical Staff in KSA: Cross Sectional Study
Authors: Balbaid Eman AbdulAziz , Abousada Hoda Jehad , Alotaibi Abdulaziz Ateeq , Alqahtani Abdullah Hazza , Alsaeedi Nashwa Nasser , Abutaleb Faisal Ali , Alrabie Majdi Abdullah , Alghamdi Rahaf Ghormallah , Bayahya Atheer Ahmed , Almutairi Basil Abdulaziz , Asiri Hanin Abdullah , Alotaibi Khalid Hazza , Aldajani Meshal Faihan , Alsaab Saad Omar , Alghamdi Renad Abdullah 
Published: January 2022

Background: According to the international classification system ICD -10 (International Classification of Diseases), doctors speak of a mild depressive episode if at least two main symptoms such as depressed mood and lack of drive and two additional symptoms such as feelings of guilt and sleep disorders occur. In a moderately depressed phase, there are two main symptoms and at least three, but no more than four other symptoms. Major depressive episodes are diagnosed when all three main symptoms and at least four additional symptoms are present. In addition, the complaints must last for at least two weeks. In the American classification system DSMIV is referred to as "major depression" (corresponds to a severe depressive episode) and "minor depression" in the case of a less severe episode.
Methods: This was an analytical cross-sectional study to spot light on the relationship between different chronic conditions and variables, specifically: age group, gender, medical specialty, years of experience, nationality, Vitamin D deficiency, Diabetes mellitus, and hypertension; and depression symptoms, among Saudi and non-Saudi medical staff in the KSA.
Results and Conclusion: Results of this study concluded that there is a significant relationship found between depressive symptoms and gender, specialty, years of experience, and vitamin D deficiency. Relationship with age group, nationality, diabetes mellitus and hypertension, is not statistically significant. These results are concordant, in most parts of this study, with the previous studies in different times and regions, done for nearly similar purposes.
Comparative Evaluation of the Success Rate of Pulpotomy in Primary Molars Using Ferric Sulphate (FS) and Mineral Trioxide Aggregate (MTA): A Clinical and Radiographic Study
Authors: Somwanshi Yogesh , Chavhan Pankaj , Sajjanar Arun , Ughade Snehal , Gutte Nutan , Kolekar Pratima , Bhamare Shruti , Yadav Swapnil 
Published: January 2022

Purpose: The aim of this present study was to observe clinical, radiographic response of pulp to Ferric Sulphate and Mineral Trioxide Aggregate when used as pulpotomy agent in primary molars.
Materials and Methods: Sixty restorable primary molars were selected for the study. The children were chosen who require minimum two pulpotomies in either arch preferably each on the opposite side (i.e. right and left). Primary molars on the right side of the patient were assigned to Ferric Sulphate (FS) (Group A) and left side was assigned for the Mineral Trioxide Aggregate (MTA) (Group B). Statistical analysis was done for pain, swelling, sinus, and fistula and for internal resorption, furcation radiolucency and periapical pathology using the chi-square test.
Results: outcome of the present study was observed at 3 month interval and after 6 months. The clinical success rate for MTA (AQUA) and ferric sulphate during 3 and 6 month follow up was 100%. The radiographic follow up of MTA was 100% during 3 and 6 month, whereas it was 96.6% for 3 and 6 month follow up with respect to ferric sulphate. There were no significant differences in the clinical (p>0.1) and radiographic (p>0.98) success rates among both the groups.
Conclusion: ferric sulphate was found to be equally effective when compared with MTA. Radiographic success rate was lower for Ferric sulphate (Group A) than that of MTA (Group B) with occurrence of one internal resorption seen with first primary molar.
The Development of Innovative Clay Mask Product Mixed with Theacanthus ebracteatus Vahl Extract
Authors: Kakatum Narin , Sookdee Papawee , Phromhan Thanaporn , Hamai Ilham , Supatsaraphokin Natphapat 
Published: January 2022

This research is a study on the development of innovative clay mask mixed with the Acanthus ebracteatus Vahl extract product. The purposes of this research are as follows. Firstly, the research is to develop a clay mask product mixed with natural extracts from the Acanthus ebracteatus Vahl. Secondly, it is aimed to study on the antioxidant activity, anti-inflammatory effect, antimicrobial effect and total Phenolic contents of the Acanthus ebracteatus Vahl extracts. Thirdly, it is tostudy stability of the product. Finally, the research is to study on the calculation of suitable product formulations for clay products mixed with Acanthus ebracteatus Vahl extracts. By starting from the selection of raw materials, the extracts are prepared to determine the total phenolic content. Later, 2,2-diphenyl-1-picrylhydrazyl (DPPH) Assay method is conducted for antioxidant activity test, followed by anti-inflammatory effect test (Nitric oxide production inhibitory activity test, inhibition of LPS-induced TNF-α secretion test and Anti-inflammatory activity test (COX-2). Afterwards, a suitable formulation is developed. The test for the safety and physical properties of the product is then carried out followed by the skin irritation test in a group of 10 volunteers in order to ensure that the clay mask product containing Acanthus ebracteatus Vahl extracts is effective and safe. From the results of the product stability study, the findings indicated that the clay mask product containing Acanthus ebracteatus Vahl extracts did not show any phase separation. The irritation test in 10 volunteers after 12 hours of using the product showed no sign of allergic reaction, itching or irritation. Toxicity test results found no cytotoxicity. The anti-inflammatory effect test was found to have potent anti-inflammatory properties, when tested in the RAW 264.7 macrophage cell. This study is only for the development of an innovative product of skin clay mask mixed with the Acanthus ebracteatus Vahl extracts.
Chalcogenide Microsphere‐Assisted Optical Super‐Resolution Imaging
Authors: Xie Yu , Cai Dawei , Pan Jing , Zhou Ning , Guo Xin , Wang Pan , Tong Limin 
Published: January 2022

AbstractMicrosphere‐assisted optical imaging has been proved straightforward and cost‐effective for super‐resolution imaging in material science and biomedical research. Optically transparent microspheres with a high refractive index are critical for achieving superior super‐resolution capabilities yet remain to be further exploited. Here, the use of As2S3 (an optically transparent chalcogenide glass) microspheres, with a refractive index as high as 2.31 (at 600 nm) and diameters ranging from 10 to 215 µm, for optical super‐resolution imaging is reported. Under white‐light illumination (peaked at 646 nm), As2S3 microspheres full‐immersed in polymethyl methacrylate or immersion oil generate super‐resolved virtual images of nanostructures (≈90 nm in minimum feature size) with a magnification up to 8×. The lateral resolution of full‐immersed microspheres, which can be as low as ≈172 nm for a 19 µm diameter As2S3 microsphere, is also investigated. Moreover, super‐resolved real imaging of nanostructures with semi‐immersed As2S3 microspheres is demonstrated for the first time. Compared with the full‐immersion approach (e.g., for a 30 µm diameter microsphere, the image plane is ≈30 µm underneath the specimen with a magnification of 4.3×), the semi‐immersion approach provides an obvious improvement in the magnification (6.6×) and a much longer operation distance to the objective (the image plane is ≈140 µm above the specimen).
Efficient and Stable Quantum‐Dot Light‐Emitting Diodes Enabled by Tin Oxide Multifunctional Electron Transport Layer
Authors: Chen Zinan , Chen Shuming 
Published: January 2022

AbstractZinc oxide (ZnO) based nanoparticles (NPs) are the most commonly used electron transport layer (ETL) materials in quantum dot light‐emitting diodes (QLEDs). However, numerous defects, severe quenching, and poor stability of ZnO NPs limit the commercialization of QLEDs. Herein, tin oxide (SnO2) NPs are prepared as a substitute to ZnO. The obtained SnO2 NPs exhibit high conductivity, good transparency, and excellent stability, thus enabling them to be applied as multifunctional ETLs for various structured QLEDs, e.g., 1) as a phase tuning layer to tune the microcavity effect in inverted QLEDs, 2) as a thick protection layer to improve the stability of noninverted QLEDs, 3) as a sputtering buffer layer to protect the functional layers from the ion bombardment damage in transparent QLEDs, and 4) as an internal light extraction layer to enhance the light coupling efficiency of top‐emitting QLEDs. With the multifunctional SnO2 ETL, the resultant QLEDs are highly efficient (external quantum efficiency of 27.6%) and stable (half lifetime of 323 h at 4,459 cd m−2), which are comparable and even better than ZnMgO based devices. The results suggest that SnO2 is a promising ETL material for realizing efficient and stable QLEDs.
Synergistic Manipulation of Na+ Flux and Surface‐Preferred Effect Enabling High‐Areal‐Capacity and Dendrite‐Free Sodium Metal Battery
Authors: Jin Qianzheng , Lu Hongfei , Zhang Zili , Xu Jing , Sun Bin , Jin Yang , Jiang Kai 
Published: January 2022

AbstractThe propensity of sodium anode to form uniform electrodeposit is bound up with the nature of electrode surface and regulation of Na‐ion flux, as well as distribution of electronic field, which is quite crucial for high‐areal‐capacity sodium metal batteries (SMBs). Herein, a novel metallic sodium/sodium–tin alloy foil anode (Na/NaSn) with 3D interpenetrated network and porous structure is prepared through facile alloy reaction. The strong sodiophilic properties of sodium–tin alloy can lower the nucleation energy, resulting in smaller depositing potential and strong adsorption of Na+, while synergistic effect of porous skeleton and additional potential difference (≈0.1 V) between Na and Na–Sn alloy (Na15Sn4) can alleviate volume expansion, redistribute the Na‐ion flux and regulate electronic field, which favors and improves homogeneous Na deposition. The as‐fabricated Na/NaSn electrode can endow excellent plating/stripping reversibility at high areal capacity (over 1600 h for 4 mAh cm−2 at 1 mA cm−2 and 2 mAh cm−2 at 2 mA cm−2), fast electrochemical kinetics (500 h under 4 mAh cm−2 at 4 mA cm−2) and superior rate performances. A novel strategy in the design of high‐performance Na anodes for large‐scale energy storage is provided.
Stress Dissipation Encoded Silk Fibroin Electrode for the Athlete‐Beneficial Silk Bioelectronics
Authors: Choi Woojin , Heo Deokjae , Kim Taeho , Jung Sungwon , Choi Moonhyun , Heo Jiwoong , Kwon Jae‐Sung , Kim Byeong‐Su , Lee Wonhwa , Koh Won‐Gun , Cho Jeong Ho , Lee Sangmin , Hong Jinkee 
Published: January 2022

AbstractThe kinetic body motions have guided the core‐shell fabrics of wearable bioelectronics to be elastoplastic. However, the polymeric electrodes follow the trade‐off relationship between toughness and stretchability. To this end, the stress dissipation encoded silk fibroin electrode is proposed as the core electrode of wearable bioelectronics. Significantly, the high degree of intrinsic stress dissipation is realized via an amino acid crosslink. The canonical phenolic amino acid (i.e., tyrosine) of silk fibroin is engineered to bridge the secondary structures. A sufficient crosslink network is constructed when tyrosine is exposed near the amorphous strand. The stress dissipative tyrosine crosslink affords 12.5‐fold increments of toughness (4.72 to 58.9 MJ m−3) and implements the elastoplastic silk fibroin. The harmony of elastoplastic core electrodes with shell fabrics enables the wearable bioelectronics to employ mechanical performance (elastoplasticity of 750 MJ m−3) and stable electrical response. The proposed wearable is capable of assisting the effective workouts via triboelectricity. In principle, active mobility with suggested wearables potentially relieves muscular fatigues and severe injuries during daily fitness.
2D/3D Hybrid Cs2AgBiBr6 Double Perovskite Solar Cells: Improved Energy Level Alignment for Higher Contact‐Selectivity and Large Open Circuit Voltage
Authors: Sirtl Maximilian T. , Hooijer Rik , Armer Melina , Ebadi Firouzeh G. , Mohammadi Mahdi , Maheu Clément , Weis Andreas , van Gorkom Bas T. , Häringer Sebastian , Janssen René A. J. , Mayer Thomas , Dyakonov Vladimir , Tress Wolfgang , Bein Thomas 
Published: January 2022

AbstractSince their introduction in 2017, the efficiency of lead‐free halide perovskite solar cells based on Cs2AgBiBr6 has not exceeded 3%. The limiting bottlenecks are attributed to a low electron diffusion length, self‐trapping events and poor selectivity of the contacts, leading to large non‐radiative VOC losses. Here, 2D/3D hybrid double perovskites are introduced for the first time, using phenethyl ammonium as the constituting cation. The resulting solar cells show an increased efficiency of up to 2.5% for the champion cells and 2.03% on average, marking an improvement by 10% compared to the 3D reference on mesoporous TiO2. The effect is mainly due to a VOC improvement by up to 70 mV on average, yielding a maximum VOC of 1.18 V using different concentrations of phenethylammonium bromide. While these are among the highest reported VOC values for Cs2AgBiBr6 solar cells, the effect is attributed to a change in recombination behavior within the full device and a better selectivity at the interface toward the hole transporting material (HTM). This explanation is supported by voltage‐dependent external quantum efficiency, as well as photoelectron spectroscopy, revealing a better energy level alignment and thus a better hole‐extraction and improved electron blocking at the HTM interface.