bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polyoxometalate‐Incorporated Host‐Guest Framework Derived Layered Double Hydroxide Composites for High‐Performance Hybrid Supercapacitor†
Authors: Zhang Yanan , Chen Junlei , Razq Fazal , Su Chenyang , Hou Xuehan , Huang Wenhuan , Zhang Huabin 
Published: September 2022

Comprehensive SummaryMetal organic frameworks have been employed as high‐performance layered double hydroxide (LDH) composite supercapacitor electrode materials but have shown unsatisfactory redox ability and stability. Herein, a host‐guest CuMo‐based polyoxometalate‐based metal organic framework (POMOF) with copious electrochemically active sites and strong electrochemical redox activities has been effectively coupled with POM‐incorporated CoNi‐LDH to develop a nanocomposite (NENU‐5@CoNi‐LDH) by a simple solvothermal method. The designed electrode shows a high specific capacity of 333.61 mAh·g–1 at 1 A·g–1. In addition, the novel hybrid symmetric supercapacitor NENU‐5@CoNi‐LDH/active carbon (AC) demonstrated a high energy density of 80.8 Wh·kg–1 at a power density of 750.7 W·kg–1. Interestingly, the nanocomposite of NENU‐5@CoNi‐LDH exhibits an outstanding capacitance retention of 79% after 5000 charge‐discharge cycles at 10 A·g–1. This work provides a new strategy and will be the backbone for future energy storage research.
Efficient multiple change point detection for high‐dimensional generalized linear models
Authors: Wang Xianru , Liu Bin , Zhang Xinsheng , Liu Yufeng ,   for the Alzheimer's Disease Neuroimaging Initiative
Published: September 2022

AbstractChange point detection for high‐dimensional data is an important yet challenging problem for many applications. In this article, we consider multiple change point detection in the context of high‐dimensional generalized linear models, allowing the covariate dimension to grow exponentially with the sample size . The model considered is general and flexible in the sense that it covers various specific models as special cases. It can automatically account for the underlying data generation mechanism without specifying any prior knowledge about the number of change points. Based on dynamic programming and binary segmentation techniques, two algorithms are proposed to detect multiple change points, allowing the number of change points to grow with . To further improve the computational efficiency, a more efficient algorithm designed for the case of a single change point is proposed. We present theoretical properties of our proposed algorithms, including estimation consistency for the number and locations of change points as well as consistency and asymptotic distributions for the underlying regression coefficients. Finally, extensive simulation studies and application to the Alzheimer's Disease Neuroimaging Initiative data further demonstrate the competitive performance of our proposed methods.
Posttransplant cyclophosphamide‐based anti–graft‐vs‐host disease prophylaxis in patients with acute lymphoblastic leukemia treated in complete remission with allogeneic hematopoietic cell transplantation from human leukocyte antigen‐mismatched unrelated donors versus haploidentical donors: A study on behalf of the ALWP of the EBMT
Authors: Nagler Arnon , Labopin Myriam , Arat Mutlu , Reményi Péter , Koc Yener , Blaise Didier , Angelucci Emanuele , Vydra Jan , Kulagin Aleksandr , Socié Gerard , Rovira Montserrat , Sica Simona , Aljurf Mahmoud , Gülbas Zafer , Kröger Nicolaus , Brissot Eolia , Peric Zinaida , Giebel Sebastian , Ciceri Fabio , Mohty Mohamad 
Published: September 2022

BackgroundBoth mismatched unrelated donor (MMUD) and haploidentical (haplo) transplantation are valid options in patients with high‐risk acute lymphoblastic leukemia (ALL) lacking a matched donor.MethodsThe study compared the outcomes of adult patients with ALL in complete remission (CR) who underwent 9/10 MMUD versus haplo transplantation with posttransplant cyclophosphamide (PTCy) as graft‐vs‐host disease (GVHD) prophylaxis in 2010–2020.ResultsThe study included 781 patients (MMUD, 103; haplo, 678). The median age was 40 (19–73) and 38 (18–75) years, respectively (p = .51). The most frequent immunosuppression agents added to PTCy were mycophenolate mofetil (MMF)/cyclosporine A and MMF/tacrolimus. In vivo T‐cell depletion (anti‐thymocyte globulin) was administered to 21% and 8% of the transplants, respectively (p < .0001). Neutrophil (absolute neutrophil count >0.5 × 109/L) recovery was achieved in 97.1% versus 96.7% versus (p = 1) in MMUD and haplo, respectively. Nonrelapse mortality and relapse incidence were not significantly different between MMUD and haplo, hazard ratio (HR) = 1.45 (95% confidence interval [CI], 0.81–2.62; p = .21) and HR = 0.81 (95% CI, 0.52–1.28, p = .38), respectively. HRs for leukemia‐free survival, overall survival, and GVHD‐free, relapse‐free survival were respectively, HR = 1.05 (95% CI, 0.73–1.50, p = .8), HR = 1.17 (95% CI, 0.77–1.76, p = .46), and HR = 1.07 (95% CI, 0.78–1.46, p = .7) for haplo compared to MMUD. Acute (a)GVHD grade 2–4 was significantly higher with haplo, HR = 1.73 (95% CI, 1.08–2.76, p = .023), whereas aGVHD grade 3–4 and chronic GVHD did not differ significantly between the two transplant groups.ConclusionOutcomes of MMUD and haplo transplants with PTCy‐based GVHD prophylaxis for ALL patients in CR are similar, apart from a higher incidence of aGVHD with haplo transplants.
Thermosensitive Liposomal Nanoplatform Based on Metal‐Free Phthalocyanine with Copper(II)‐Regulated Photoactivities
Authors: Ma Xin‐Yue , Zhang Wen , Que Rong‐Bin , Wang Chao , Shang Wen‐Wen , Zhu Yuan‐Yuan , Zheng Bi‐Yuan , Chen Yu , Ke Mei‐Rong , Huang Jian‐Dong 
Published: September 2022

AbstractThis work reports the development of a multifunctional thermosensitive liposomal nanoplatform (PcS4@Lip‐FA) based on a metal‐free phthalocyanine modified with tetra‐sulfonates (PcPS4), which exhibited photodynamic and photothermal activities simultaneously. Upon irradiation with a near infrared laser, thermosensitive PcS4@Lip‐FA could release PcS4 as a result of the local hyperthermia of PcS4. Interestingly, PcS4 could easily chelate with Cu2+, leading to the enhancement of photothermal activity and decrease of photodynamic activity. In addition, in vivo fluorescence imaging revealed that PcS4@Lip‐FA could selectively accumulate in tumor tissue of H22 tumor‐bearing mice after tail vein injection, and exhibited a significant anticancer phototherapeutic effect, with a tumor inhibition rate of 83.5 %. Therefore, PcPS4@Lip‐FA has realized fluorescence imaging‐guided combined cancer treatment, providing a promising multifunctional nanoplatform for cancer diagnostics and therapy.
Synthesis and Structural Diversification of Circularly Polarised Luminescence Active, Helically Chiral, “Confused” N,N,O,C‐BODIPYs**
Authors: Clarke Rebecca G. , Weatherston Jake , Taj‐Aldeen Rafid A. , Waddell Paul G. , McFarlane William , Penfold Thomas J. , Bogaerts Jonathan , Herrebout Wouter , Mackenzie Lewis E. , Pal Robert , Hall Michael J. 
Published: September 2022

AbstractHelically chiral boron‐chelated dipyrromethene (BODIPY) dyes are known to exhibit solution phase circularly polarized luminescence (CPL), but examples are limited to a few synthetically accessible molecular architectures. We report a B−N chelation, SNAr, Suzuki cross‐coupling, B−O chelation cascade reaction for the synthesis of understudied helically chiral, N,N,O,C‐boron chelated, “confused” BODIPYs, from readily accessible 3,5‐dibromo‐BODIPY starting materials. Using this approach we have prepared a series of helically chiral “confused” BODIPYs with variation of the 3,5‐subsitutents. Following resolution by chiral HPLC, absolute stereochemistry was assigned through comparison of the experimental and calculated ECD spectra, and solution phase chiroptical properties including CPL were determined (|glum| from 2.1 to 3.7×10−3; BCPL from 11.3 to 27.2).
Non‐Metallic Phosphorus Corrole as Efficient Electrocatalyst in Hydrogen Evolution Reaction
Authors: Yang Gang , Cen Jing‐He , Lan Jian , Li Meng‐Yuan , Zhan Xuan , Yuan Gao‐Qing , Liu Hai‐Yang 
Published: September 2022

AbstractThe economical consideration of using an electrocatalyst in energy‐related field, composed of non‐precious/sustainable elements is quite noteworthy. In this work, the phosphorus(V) complex of tris‐(pentafluorophenyl)corrole [(TPFC)PV(OH)2] was reported as electrocatalyst for the hydrogen evolution reaction (HER). The electrochemical studies revealed that the HER experienced a ECEC pathway (E: electron transfer step, C: chemical step), and the possible intermediate [PV]−H species was suggested. (TPFC)PV(OH)2 displayed excellent HER activity in dimethylformamide (DMF) with trifluoroacetic acid (TFA) as the proton source, and the turnover frequency (TOF) reached 31.75 s−1 at an overpotential of 900 mV. Interestingly, the HER electrocatalytic performance remained extraordinary even applying water as a proton source in acetonitrile/water (v/v=2 : 3), with a TOF of 18.40 mol
molcat−1 h−1 at an overpotential of 900 mV.
Seven‐level triple boost self‐balanced switched‐capacitor inverter
Authors: Yarlagadda Anil Kumar , Verma Vimlesh 
Published: September 2022

AbstractSwitched‐capacitor multi‐level inverters (SCMLIs) have become more popular in recent years due to their unique advantage of voltage boosting capability. A seven‐level triple boost SCMLI is proposed in this paper. The proposed topology consists of 10 switches, one diode, three self‐balanced capacitors, and a DC source. The voltage stress on each switch is less than or equal to twice the input DC source voltage. Further, 4 out of 10 switches are switched at the fundamental frequency. The maximum conducting switches at each level is less than or equal to 4. The capacitors are self‐balanced without using any voltage sensors or external circuits. A detailed comparison has been given with the existing seven‐level triple boost SCMLI to show the superiority of the proposed topology. The seven‐level triple boost SCMLI is simulated using MATLAB/SIMULINK tool. The proposed model is verified at low‐ and high‐frequency switching, sudden changes in output load, and different modulation index values. The results are verified experimentally with the help of a prototype model developed in the laboratory using dSPACE 1104.
The Ecologist's Career Compass: A game to explore career paths
Authors: Itescu Yuval , Bernard‐Verdier Maud , Moesch Simon S. , Mrugała Agata , Mrugała Kinga , Musseau Camille L. , Jeschke Jonathan M. 
Published: September 2022

AbstractOne of the most challenging endeavors for students is choosing a career path that best fits their interests, wills and skills, and setting their professional goals accordingly. Such decisions are often made from within the culture of academia, in which mentors and peers are mainly familiar with the academic job market and lack the knowledge necessary to consult about other types of careers. We aimed to address this gap for ecology and related fields by creating an engaging and effective tool to help students and professionals to familiarize themselves with the diversity of potential career paths available to ecologists. The tool is an applied card game – the Ecologist's Career Compass – which is provided here freely. The game is played as a trump card game and includes 33 cards, each representing a combination of one of four job‐market sectors and one of nine types of positions. Each card indicates the level of seven skill categories required to likely be hired and succeed in the focal position at the focal sector, as well as more specific examples for typical jobs in the focal combination. The information in the game largely relies on input from a global survey we conducted among 315 ecologists from 35 countries. While the challenges faced by early‐career ecologists in developing their professional path are substantial and diverse, this game can assist in gaining a broad comparative overview of the whole ecology job market and the skills required to likely excel in different paths. We hope this applied game will act as a conversation starter about the diversity of aspirations and opportunities in ecology classrooms and labs.
Incidence and impact of atrial fibrillation in heart failure patients: real‐world data in a large community
Authors: Diaz Javier , Martinez Fernando , Calderon Jose Miguel , Fernandez Antonio , Sauri Inmaculada , Uso Ruth , Trillo Jose Luis , Redon Josep , Forner Maria Jose 
Published: September 2022

AbstractAimsThe objective of the present study is to assess the bidirectional association between heart failure (HF) and atrial fibrillation (AF) using real‐world data.Methods and resultsFrom an electronic health recording with a population of 3 799 885 adult subjects, those with prevalent or incident HF were selected and followed throughout a study period of 5 years. Prevalence and incidence of AF, and their impact in the risk for acute HF hospitalization, worsening renal function, ischaemic and haemorrhagic stroke, and all‐cause mortality were identified. We analysed all incident and prevalent patients with HF and AF, 128 086 patients (S1), and subsequently analysed a subset of patients with incident HF and AF, 57 354 patients (S2). We analysed all incident and prevalent patients with HF and AF, 128 086 patients (S1), and subsequently a subset of patients with incident HF and AF, 57 354 patients (S2). The prevalence of AF was 59 906 (46.7%) of the HF patients, while incidence in the S2 was 231/1000 patients/year. In both cohorts, S1 and S2, AF significantly increases the risk of acute heart failure hospitalization [incidence 79.1/1000 and 97.5/1000 patients/year; HR 1.53 (1.48–1.59 95% CI) and HR 1.32 (1.24–1.41 95% CI), respectively], risk of decreased renal function (eGFR reduced by >20%) [66.2/1000 and 94.0/1000 patients/year; HR 1.13 (1.09–1.18 95% CI) and HR 1.22 (1.14–1.31 95% CI), respectively] and all‐cause mortality [203/1000 and 294/1000 patients/year; HR 1.62 (1.58–1.65 95% CI) and HR 1.65 (1.59–1.70 95% CI), respectively]. The number of episodes of hospitalization for acute heart failure was also significantly higher in the AF patients (27 623 vs. 10 036, P < 0.001). However, the risk for ischaemic stroke was reduced in the AF subjects [HR 0.66 (0.63–0.74 95% CI)], probably due to the anticoagulant treatment.ConclusionsAF is associated with an increment in the risk of episodes of acute heart failure as well as decline of renal function and increment of all‐cause mortality.
Novel Approaches To Design Glycan‐Based Antibacterial Inhibitors
Authors: Behren Sandra , Westerlind Ulrika 
Published: September 2022

AbstractThe interactions between bacterial lectins and carbohydrates on the host cell surface can mediate bacterial adhesion, invasion, and immune evasion. Multivalency plays a key role in these binding events. However, additional molecular mechanisms greatly impact multivalent binding recognition. To develop specific and effective bacterial inhibitors, a deeper understanding of the complex underlying mechanisms of bacterial adhesion processes is necessary. By interfering with bacterial adhesion, synthetic multivalent glycoconjugates do not only have the potential to improve or replace antibiotic treatments, but also represent useful tools to study carbohydrate‐pathogen interactions. In this review, we highlight a few recent advances in the synthesis and application of synthetic glycan‐based scaffolds to uncover the nature of glycan‐bacteria interactions and to design efficient bacterial inhibitors.
An explicit symplectic approach to solving the wave equation in moving media
Authors: Inguva Venkatesh , Feldmann Nadine , Claes Leander , Koturbash Taras , Hahn‐Jose Thomas , Koutcherov Vladimir , Kenig Eugeny Y. 
Published: September 2022

AbstractAn explicit approach using symplectic time integration in conjunction with traditional finite difference spatial derivatives to solve the wave equation in moving media is presented. A simple operator split of this second order wave equation into two coupled first order equations is performed, allowing these split equations to be solved symplectically. Orders of symplectic time integration ranging from first to fourth along with orders of spatial derivatives ranging from second to sixth are explored. The case of cylindrical acoustic spreading in air under a constant velocity in a 2D square structured domain is considered. The variation of the computed time‐of‐flight, frequency, and wave length are studied with varying grid resolution and the deviations from the analytical solutions are determined. It was found that symplectic time integration interferes with finite difference spatial derivatives higher than second order causing unexpected results. This is actually beneficial for unstructured finite volume tools like OpenFOAM where second order spatial operators are the state‐of‐the art. Cylindrical acoustic spreading is simulated on an unstructured 2D triangle mesh showing that symplectic time integration is not limited to the spatial discretization paradigm and overcomes the numerical diffusion arising with the in‐built numerical methods which hinder wave propagation.
Aeolization on the Atlantic coast of Galicia (NW Spain) from the end of the last glacial period to the present day: Chronology, origin and evolution of coastal dunes linked to sea‐level oscillations
Authors: Arce Chamorro Carlos , Vidal Romaní Juan Ramón , Grandal d'Anglade Aurora , Sanjurjo Sánchez Jorge 
Published: September 2022

AbstractThe Atlantic coast of Galicia (NW Spain) is a high‐energy environment where shingle beaches are currently developing. These coarser sediments alternate with sandy deposits which are also considered as beaches typical of a low‐energy environment. The physical association of both types of sediment with contrasted sedimentary significance raises problems of interpretation. The study of four outcrops of fossil aeolianites on this coast has allowed us to reconstruct their evolution from the end of the Upper Pleistocene to the present day. Their chronology, estimated by optically stimulated luminescence between 35 and 14 ky at the end of the last glaciation (MIS2), coincides with a local sea level 120 m below the present one. This implies a coastline shifted several kilometres from its current location and the subaerial exposure of a wide strip of the continental shelf covered by sands. The wind blew sand to form dunes towards the continent, covering the coastal areas, which then emerged with no other limitation than the active river channels. Sea‐level rise during the Holocene transgression has progressively swamped these aeolian deposits, leaving only flooded dunes, relict coastal dunes and climbing dunes on cliffs up to 180 m high. The aeolian process continued as long as there was a sandy source area to erode, although accretion finished when the sea reached its current level (Late Holocene). Since then, the wind turned from accretion to erosion of the dunes and sand beaches. This erosion exposes the older shingle beaches (probably of Eemian age) buried under the aeolian sands, as well as old, submerged forest remains and megalithic monuments. The destruction of sand beaches and dunes currently observed along the Galician coast is linked, according to most researchers, to anthropogenic global warming. However, their management should consider these evolutive issues.
Plant-associate interactions and diversification across trophic levels
Authors: Yoder Jeremy B. , Dang Albert , MacGregor Caitlin , Plaza Mikhail 
Published: September 2022

AbstractInteractions between species are widely understood to have promoted the diversification of life on Earth, but how interactions spur the formation of new species remains unclear. Interacting species often become locally adapted to each other, but they may also be subject to shared dispersal limitations and environmental conditions. Moreover, theory predicts that different kinds of interactions have different effects on diversification. To better understand how species interactions promote diversification, we compiled population genetic studies of host plants and intimately associated herbivores, parasites, and mutualists. We used Bayesian multiple regressions and the BEDASSLE modeling framework to test whether host and associate population structures were correlated over and above the potentially confounding effects of geography and shared environmental variation. We found that associates' population structure often paralleled their hosts' population structure, and that this effect is robust to accounting for geographic distance and climate. Associate genetic structure was significantly explained by plant genetic structure somewhat more often in antagonistic interactions than in mutualistic ones. This aligns with a key prediction of coevolutionary theory that antagonistic interactions promote diversity through local adaptation of antagonists to hosts, while mutualistic interactions more often promote diversity via the effect of hosts' geographic distribution on mutualists' dispersal.
Come Correct: Itineraries of Discovery in Black Women's Ethnographic Practice
Authors: Strong Krystal , Blanks Jones Jasmine 
Published: September 2022

AbstractThis methodological reflection invokes the legacy of Black women anthropologists, who have approached ethnography not as encounters with “The Other” but as part of African Diasporic projects. As two U.S. Black women ethnographers, who understand our fieldwork contexts in West Africa as sites of return, re‐discovery, and struggle, we situate our work within Black feminist genealogies, which refashion anthropological tools to re‐map and reconstitute relations and recognition amongst those we call our kinfolk. We draw on “co‐performative witnessing” (Madison 2007) and “mutual comradeship” (Burden‐Stelly 2018) as counter‐modalities of ethnographic praxis, which follow in this tradition of disrupting and re‐routing the disciplinarily legitimized stakes of ethnography. Specifically, we re‐narrate gatherings, by which we mean moments of being “gathered,” or collected and corrected in love. Within our respective “itineraries of discovery” (Walker 2015) in Liberia and Nigeria, we were confronted with dilemmas of personal and professional benefit in youth performance ethnography and challenged to relinquish political neutrality in activist ethnography. We conclude by amplifying the call of Black women anthropologists and our kinfolk interlocutors that when we come to our ethnographic work, physically, intellectually, and relationally, that we also “come correct.”
Arrhenius energy effect on the rotating flow of Casson nanofluid with convective conditions and velocity slip effects: Semi‐numerical calculations
Authors: Ibrahim Mohamed G. , Fawzy N. A. 
Published: September 2022

AbstractThe present paper focuses on the effects of Arrhenius activation energy on the hydromagnetic rotating flow of Casson nanofluid. Entropy production, viscous dissipation Brownian dispersion, porous medium, velocity slip, magnetic field, convective heat, and mass conditions are taken into consideration. Transformation schemes are used to extract a nonlinear system of the differential equation. The generalized differential transform method (GDTM) is used to compute/obtain the solutions of the present system. Results for the distributions of velocities, nano concentration, and temperature are scrutinized graphically. The accuracy of GDTM is proved via a comparison of numerical and graphical results with the nearest published results by Hayat et al. and found to be excellent. Graphical results are extracted for different values of pertinent parameters versus velocities, nano concentration, and temperature profiles. The results show that more heat is produced due to the process of thermal radiation for which entropy is knowingly improved.