bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improved Management Teacher Professional Education Program Surabaya State University Through Alumni Tracer (Tracer Study)
Authors: Sampun Julianto 
Published: May 2022

Abstract: The mandate of Law Number 14 of 2005 concerning Teachers and Lecturers states that teachers are required to have academic qualifications, competencies, educator certificates, physically and mentally healthy, and have the ability to realize national education goals. The preparation of teachers as professional educators is also stated in Government Regulation Number 19 of 2017 concerning Amendments to Government Regulation Number 74 of 2008 concerning Teachers. The State University of Surabaya has been trusted to implement PPG In Position (Daljab) starting in 2018 – now which is being funded by APBN funds. The purpose of this study is to identify and obtain various information related to the level of satisfaction of PPG graduates who participate in PPG activities at the State University of Surabaya. The type of research used is descriptive research. The population in this study is all PPG participants in the range of 2018 - 2020. The samples used in this study are representatives of PPG who have graduated in 2018-2020 for the Madiun, Ngawi and Magetan areas along with the principals where PPG alumni teach. Data collection methods used are interviews and questionnaires. The data obtained will be analyzed descriptively qualitatively and quantitatively. Based on the results and discussion of the data obtained, it can be concluded that the level of management in the implementation of PPG Unesa received a good - very good response. This is indicated by the responses given by PPG Unesa student alumni through a questionnaire distributed using the google form.
PROFILE AND PATIENT ACUTE HEPATITIS CHILDREN OUTPUT IN DR SOEBANDI JEMBER HOSPITAL
Authors: Adita Rini Ika Wahyu , Shodikin M. Ali 
Published: May 2022

Background: Indonesia is an endemic area for Hepatitis akut. District of Jember determines the status of extraordinary event Hepatitis akut at the end of 2019. The purpose of this study was the profile and patient acute hepatitis children output in dr Soebandi Jember Hospital in December 2019 until January 2020.
Methods: This study was retrospective descriptive. The material was taken of the medical records Hepatitis akut patient at the pediatric departement of the dr. Soebandi Hospital in Jember.
Results: In this study, patients most often occurred in male, age ranged between 7 – 14 years, and lived on the villages. The most common of clinical manifestation are anorexia, jaundice, fever, hepatomegaly, dark urine, vomiting and abdominal pain. The result of laboratory examination showed that Hepatitis acut patient had elevated of SGOT , SGPT, direct and total bilirubin.
Conclusions: The combination of curcuma with SNMC (Stronger Neo-Minophagen C) reductly significant SGOT and SGPT serum levels (p < 0,001).
Pentaksiran Bilik Darjah (PBD) Dalam Norma Baharu: Pemimpin Pertengahan Dalam Mengupayakan Pelaksanaan PBD Berasaskan Teknologi
Authors: Arumugham Kalai Selvan 
Published: May 2022

Pengenalan PBD adalah bertujuan untuk memastikan perkembangan pembelajaran seseorang pelajar dapat diukur secara berterusan. Walau bagaimanapun, sejak pengajaran dan pembelajaran dari rumah (PdPr) diperkenalkan, guru menghadapi masalah untuk melaksanakan PBD dengan berkesan. Kajian ini dijalankan untuk meneroka dan memahami cara pemimpin pertengahan memainkan peranan sebagai seorang pemimpin instruksional dan seterusnya membangunkan guru-guru di sekolah untuk memastikan guru-guru dapat melaksanakan PBD dengan berkesan dengan penggunaan teknologi. Seramai lapan orang Guru Kanan Mata Pelajaran (GKMP) telah dipilih untuk menjadi peserta kajian ini. Data telah dikumpulkan dengan menggunakan temu bual separa struktur dan analisis dokumen. Data telah dianalisis berdasarkan tema-tema yang telah dikenalpasti. Melalui kajian ini didapati GKMP telah menjalankan pemantauan dan pencerapan bilik darjah sepanjang tempoh PdP. Data pencerapan mendapati guru-guru melaksanakan PBD sepanjang PdPr namun pelaksanaannya kurang bersifat pengintegrasian. Oleh itu, GKMP telah menjalankan program-program pembangunan kapasiti guru yang membantu guru mengintegrasikan PBD ke dalam PdPr dengan menggunakan teknolgi. GKMP haruslah mempunyai pendedahan dalam teknologi untuk membantu guru menggunakan teknolgi dalam pengajaran dan pembelajaran. Dicadangkan kajian lanjut dijalankan untuk melihat cara guru-guru yang mendapat pendedahan tentang teknolgi ini melaksanakan PBD secara alam maya.

The introduction of PBD is intended to ensure that a student's learning development can be measured continuously. However, since the introduction of home teaching and learning (PdPr), teachers have faced problems to implement PBD effectively. This study was conducted to explore and understand how middle leaders play a role as an instructional leader and further develop teachers in schools to ensure that teachers can implement PBD effectively with the use of technology. A total of eight Senior Subject Teachers (GKMP) were selected to be participants in this study. Data were collected using semi -structured interviews and document analysis. Data were analyzed based on the themes that had been identified. Through this study, it is found that GKMP has conducted classroom monitoring and observation during the PdPr period. Observational data found that teachers implement PBD throughout PdPr but its implementation is less integrated. Therefore, GKMP has conducted teacher capacity building programs that help teachers integrate PBD into PdPr by using technology. GKMP should have exposure in technology to help teachers use technology in teaching and learning. It is suggested that further research be conducted to see how teachers who are exposed to this technology implement PBD in cyberspace.
Effect of Water-soluble Polysaccharides Plant Extraction of the <i>Saussurea</i> Genus on the Activity of Mice Peritoneal Macrophage NO-synthase
Authors: Ligacheva A. A. , Gulina E. I. , Shabanova I. V. , Trofimova E. S. , Krivoshchekov S. V. , Gurkin N. V. , Shurupova M. N. , Sherstoboev E. Yu. , Danilets M. G. , Belousov M. V. 
Published: May 2022

Introduction. The nitric oxide molecule is one of the most versatile, multifunctional mediators of biological reactions in the body. NO participates in the formation of innate and specific immunity, the inflammatory process and protection against infectious pathogens. It is known that polysaccharides of higher plants are widely used to activate pro- and anti-inflammatory reactions. Previous studies have shown the promise of a more detailed research in the immunomodulatory properties of plant polysaccharides of the genus Saussurea DC, the mechanisms of their immunostimulating and anti-inflammatory action depending on the origin and conditions of extraction.Aim. The aim of present research was to evaluate the dependence of the affection of the extraction parameters of water-soluble polysaccharides (WSPS) from the aerial parts of S. salicifolia (L.) DC., S. controversa DС., S. frolovii Lebeb. on NO synthase activity and peritoneal macrophages proliferation.Materials and methods. Chemical methods for the isolation of water-soluble polysaccharides, cultural and biochemical methods for assessing biological activity were used.Results and discussion. Water-soluble polysaccharides (WSPS) from plants S. salicifolia (L.) DC., S. controversa DС., S. frolovii Ledeb. obtained with different extraction parameters have the ability to enhance production of nitrites antigen-presenting cells in the same way as standard macrophage activator liposaccharide. Polysaccharides from S. controversa and S. frolovii at acidic extractant are free of endotoxin impurities. All water-soluble polysaccharide samples obtained using neutral and alkaline extractants contain endotoxin impurities. Samples from the S. controversa contained this impurity after extraction in an acidic extractant. Polysaccharide samples are not cytotoxic.Conclusion. It was stated that water-soluble polysaccharides from plants of the Saussurea genus using an acidic extractant do not possess cytotoxic properties, do not contain endotoxin impurities and significantly enhance the production of nitric oxide by macrophages. These samples used in a detailed study of the immunomodulatory properties and further development on their basis of new treatment methods various diseases that require correction and regulation of the functional activity of immune cells, including macrophages.
Development and Study of Bacteriophage-containing Dosage Form for the Treatment of the Outer Ear Infections
Authors: Bakhrushina E. O. , Anurova M. N. , Bochkareva S. S. , Vorobev A. M. , Shcherbina Yu. O. , Pasivkina M. A. , Krekhtunova L. O. , Demina N. B. , Aleshkin A. V. 
Published: May 2022

Introduction. Infectious otitis externa and middle ear can cause hearing loss, which significantly reduces the quality of life of patients. The main causative agents of acute bacterial otitis media are Pseudomonas aeruginosa and Staphylococcus aureus. This article is devoted to the development and study of a novel dosage form for treatment of infectious diseases of the external ear containing bacteriophages that lyse bacterial strains of Pseudomonas aeruginosa. Ear drops were considered as a promising dosage form for instillation into the ear canal.Aim. The aim of the work is to develop a dosage form of Pseudomonas aeruginosa bacteriophages for the local treatment of infectious otitis media.Materials and Methods. The active substances of the developed drug are bacteriophages that lyse bacterial strains of Pseudomonas aeruginosa: PA5 and PA10, which were obtained by growing on a solid growth medium in mattress flasks with subsequent sterilizing filtration through a membrane filter (0,22 µm) and elimination of endotoxins on a chromatographic column. To obtain experimental compositions, excipients that do not cause a drop in the titer of bacteriophages were used – purified water as the solvent, viscosity modifiers: glycerol (CHIMMED, Russia) and a mix of macrogol 6 and glyceryl caprilocaprate brand Softigen 767 (Cremer, Germany), antioxidant Ethylenediaminetetraacetic acid (EDTA), preservatives nipagin and nipazole. The obtained samples were standardized according to pharmacopoeial indicators, recommended for the dosage form "drops" – density, pH, viscosity. For all experimental compositions, the stability of the titer of bacteriophages was studied by the Gratia method for 6 months. The local irritation and systemic effects were also studied on five chinchilla male rabbits.Results and discussion. As a result of the conducted research, four experimental compositions of ear drops with a cocktail of bacteriophages PA5 and PA10 were obtained. The optimal technological characteristics were observed in the composition containing glycerol as a viscosity modifier at a concentration of 10,0 %. For optimal composition, the stability of the bacteriophages cocktail titer, local irritating and systemic effects were analyzed. The study revealed stability of the bacteriophages PA5 and PA10 titers in the composition of dosage form, and absence of local irritating and systemic effects of ear drops.Conclusion. The dosage form can be recommended for preclinical studies.
The Effect of Different Physiotherapy Programs on Pain, Balance and Trunk Functional Capacity in Adolescents with Low Back Pain
Authors: Budrienė Lina , Gudaitė Gabrielė 
Published: May 2022

Background. Low back pain is a common problem, adversely affecting balance and strategy for controlling the trunk muscles. There are various methods to treat low back pain, therefore, studies comparing the effectiveness of different programs can help improve the rehabilitation program for patients with low back pain.
The aim. To evaluate the effect of trunk stabilization and balance exercises performed with different devices on pain, balance and trunk functional capacity in adolescents with low back pain.
Methods. 12 adolescents with low back pain participated in this study. They were divided into two groups. The first group received 20 minutes of stabilization exercises and 10 minutes of balance training using the Biodex balance system. The second group received 20 minutes of stabilization exercises and 10 minutes of balance training using a vibration platform. All subjects were evaluated before and after 10 physiotherapy procedures. Self-reported pain, balance and static endurance of trunk muscles were assessed before and after the interventions.
Results. Both programs significantly reduced pain, improved control of the center of gravity within the base of support, reduced the time required to shift weight in different paths, reduced sway index in conditions of eyes open or eyes closed on a firm or foam surface, improved dynamic and static overall postural stability and increased static endurance of trunk muscles. Improvement in control of the center of gravity within the base of support, and reduction in the time required to shift weight in different paths, were more significant in the group that received balance training using the Biodex balance system compared with that in the group that received balance training using a vibration platform.
Conclusions. Balance training using the Biodex balance system was more effective in improving control of the center of gravity within the base of support and reducing the time required to shift weight in different paths than balance training using a vibration platform.
Keywords: low back pain, balance, trunk stability, Biodex balance system, vibration platform.
Persepsi Santri Mengenai Nilai Edukatif pada Pemilahan Sampah Organik dan Non Organik di Nurul Jadid
Authors: Warliah Wiwin , Ni'mah Muliatin , Afif Nur , Maulidiyah Nurul , Devi Ika , Honifah Siti Nur , Fitriyah Laili , Isti'ana Isti'ana , Sakinah Nur 
Published: May 2022

Penelitian ini ingin mengetahui persepsi santri terhadap nilai edukasi pemilahan sampah organik dan non organik yang dilaksanakan santri di Pondok Pesantren Nurul Jadid. Hal ini penting untuk dilakukan mengingat masih banyaknya santri yang belum memahami secara hakiki antara sampah organik dan non organik. Adapun jenis penelitian yang digunakan dalam penelitian ini ialah penelitian kualitatif dengan pendekatan deskriptif, di mana data yang dikumpulkan berupa kata dan gambar. Objek penelitian ini berasal dari santri di Pondok Pesantren Nurul Jadid, dengan teknik pengumpulan data melalui observasi, wawancara, pengamatan. Hasil dari penelitian ini menunjukkan bahwa para santri melakukan pemilahan sampah terlebih dahulu sebelum diangkut oleh petugas TPS berdasar jenis sampah non organik dan organik. Sampah organik yang berasal dari dari rumput-rumput, sisa-sisa makanan atau sesuatu yang sifatnya mudah membusuk dan terurai dilainkan dalam kantong terpisah dengan sampah yang dihasilkan dari proses teknologi yang susah diurai seperti botol kemasan, atau kertas. Selain itu, perilaku dan sikap para santri telah mengalami perubahan yang disebabkan mereka telah memperoleh pengetahuan dan keterampilan baru di dalam menjaga lingkungan kebersihan mereka.
CeO2 Structure Adjustment by H2O via the Microwave–Ultrasonic Method and Its Application in Imine Catalysis
Authors: Chang Xijiang , Ding Huihui , Yang Jingxia 
Published: May 2022

CeO2 with fusiform structures were prepared by the combined microwave–ultrasonic method, and their morphologies and surface structure were changed by simply adding different amounts of H2O (1–5 ml) to the precursor system. The addition of H2O changed the PVP micelle structure and the surface state, resulting in CeO2 with a different specific surface area (64–111 m2 g−1) and Ce3+ defects (16.5%–28.1%). The sample with 2 ml H2O exhibited a high surface area (111.3 m2∙g−1) and relatively more surface defects (Ce3+%: 28.1%), resulting in excellent catalytic activity (4.34 mmol g−1 h−1).
Cardiotoxicity Related to Immune Checkpoint Inhibitors: A Real-World Retrospective Analysis
Authors: She Jianqing , Liu Hui , Wu Haoyu , Tuerhongjiang Gulinigaer , Zheng Tao , Bai Ling 
Published: May 2022

BackgroundCardiotoxicity related to immune checkpoint inhibitors (ICIs) is a rare but potentially lethal. In ICI-associated adverse events, evidence of cardiotoxicity and clinical predictive factors related to ICI is lacking. Here, we aim to assess the incidence and predictive factors of cardiotoxicity related to ICIs in real-world practice.ObjectiveWe retrospectively analyzed consecutive patients who received PD-1 or PD-L1 at the First Affiliated Hospital of Xi'an Jiaotong University. Clinical characteristics and cardiac lesion markers were collected both at baseline and during longitudinal follow-up from the Biobank database. Follow-up CKMB and NT-proBNP levels and ratios were then evaluated.ResultsA total of 2,304 patients with either PD-1 or PDL-1 utilization between August 2018 and April 2021 were collected. The average age was 59.44 ± 11.45 among PD-1 inhibitor utilizer and 58.97 ± 12.16 among PDL-1 inhibitor utilizer. The baseline creatine kinase isoenzyme MB (CKMB) levels were 17 ± 19 U/L in PD-1 inhibitor users and 17 ± 23 U/L in PDL-1 inhibitor users. Majority of patients were male, with advanced stage cancer, and received ICIs as second-line therapy. The longitudinal change of cardiac enzymes and NT-pro BNP were collected. Cardiac lesion as defined by three times increase of CKMB happens in only minority of patients receiving ICIs therapy. It is also identified that increased CKMB happened in PD-1 inhibitor groups, but not PDL-1 inhibitor groups.ConclusionWe evaluated the profile of cardiotoxicities caused by ICIs based on real-world experience. The cardiac lesion markers are generally unaltered, but it appears that the increased CKMB happened in PD-1 inhibitor groups, but not PDL-1 inhibitor groups.
Tidal Modulation of a Lateral Shear Margin: Priestley Glacier, Antarctica
Authors: Still Holly , Hulbe Christina , Forbes Martin , Prior David J. , Bowman M. Hamish , Boucinhas Bia , Craw Lisa , Kim Daeyeong , Lutz Franz , Mulvaney Robert , Thomas Rilee E. 
Published: May 2022

We use high resolution, ground-based observations of ice displacement to investigate ice deformation across the floating left-lateral shear margin of Priestley Glacier, Terra Nova Bay, Antarctica. Bare ice conditions allow us to fix survey marks directly to the glacier surface. A combination of continuous positioning of a local reference mark, and repeat positioning of a network of 33 stakes installed across a 2 km width of the shear margin are used to quantify shear strain rates and the ice response to tidal forcing over an 18-day period. Along-flow velocity observed at a continuous Global Navigation Satellite Systems (GNSS) station within the network varies by up to ∼30% of the mean speed (±28 m a−1) over diurnal tidal cycles, with faster flow during the falling tide and slower flow during the rising tide. Long-term deformation in the margin approximates simple shear with a small component of flow-parallel shortening. At shorter timescales, precise optical techniques allow high-resolution observations of across-flow bending in response to the ocean tide, including across-flow strains on the order of 10–5. An elastodynamic model informed by the field observations is used to simulate the across-flow motion and deformation. Flexure is concentrated in the shear margin, such that a non-homogeneous elastic modulus is implied to best account for the combined observations. The combined pattern of ice displacement and ice strain also depends on the extent of coupling between the ice and valley sidewall. These conclusions suggest that investigations of elastic properties made using vertical ice motion, but neglecting horizontal displacement and surface strain, will lead to incorrect conclusions about the elastic properties of ice and potentially over-simplified assumptions about the sidewall boundary condition.
Variability of Sea Breezes Over the Cameroonian Coast and Their Interaction With the West African Monsoon
Authors: Kouogang Tchuenkam Fabius Cédric , Mama Anselme Crépin , Gah-Muti Salvanus Yevalla , Araujo Moacyr 
Published: May 2022

The sea breeze characteristics of over two coastal areas of Cameroon were studied. The study used 3-hourly wind (speed and direction), rainfall, and atmospheric pressure data of 4 years (2006–2009) at Tiko and 5 years (2011–2015) at Ebodje to examine various characteristics of sea breezes. Statistics are presented that describe the occurrence, onset and cessation, and strength of the sea breezes. The frequency of occurrence clearly shows two regimes by two maxima (November and March) at Tiko and (January and July) at Ebodje. The results show that a sea breeze usually starts few hours (about 3–4 h) after the sunrise as a light onshore surface wind, has a mean duration of about 9 h at Tiko, and occurs during all seasons at both coastal areas. The sea breeze occurrence is found to be strongly influenced by the West African monsoon winds, and its onset and cessation times show a pronounced seasonal variation. The sea breeze strength is greater at Tiko than that at Ebodje during the West African monsoon season. Average daily hodographs for Tiko reveals that the sea breeze circulation is in both clockwise and anticlockwise rotation. There would be a significant seasonal effect of large-scale flows on sea breeze hodograph patterns. A wind roses analysis at Ebodje shows a high temporal variability of sea breeze frequencies at 09:00 (Local Standard Time: LST) in the south direction (36%), then at 15:00 LST in the west direction (26%), because of the preponderance of calm atmospheric situations conducive to its onset. Therefore, the circulation of the sea breeze is influenced by local factors (topography and vegetation). This phenomenon in the coastal regions of Cameroon can be the main factor controlling the transport of accidental near shore oil slicks and air pollutants.
Modeling Mesoscale Eddies Generated Over the Continental Slope, East Antarctica
Authors: Zhang Li , Liu Chengyan , Sun Wenjin , Wang Zhaomin , Liang Xi , Li Xiang , Cheng Chen 
Published: May 2022

Mesoscale eddies are abundant over the Antarctic continental slope, with the potential to regulate the water masses transport, mixing, and energy transfer. Over the relatively cold and fresh shelf regions around the Antarctic margins, in the absence of dense overflows, the baroclinic instability of the Antarctic Slope Current is still favorable in the generation of mesoscale eddies. However, mesoscale eddies are barely observed over the fresh shelf regions due to the sparsity of in situ hydrographic observations. Based on an idealized eddy-resolving coupled ocean-ice shelf model, this study investigates the characteristics of mesoscale eddies and corresponding influences on the local hydrographic properties over the continental slope, East Antarctica. With the aid of an automated eddy detection algorithm, bowl-shaped eddies are identified from the simulated velocity vector geometry. The Cyclonic Eddies (CE) has a barotropic vertical structure extending to more than 2,500 m depth, while the vertical shear of the Anticyclonic Eddies (AE) velocity is strong at the upper 200 m layer. Mesoscale eddies can trap the cold and fresh water in the southern flank of the Antarctic slope front and flow offshore to the relatively warm and saline region. Therefore, the influences of eddies on the hydrographic properties are not only governed by the eddy polarities but also the eddy-induced heat and salt transport.