bluuebunny/crossref_metadata_2025_split huggingface dataset:
Potential Anti-Depressive Effects and Mechanisms of Zhi-Zi Hou-Po Decoction Using Behavioral Despair Tests Combined With in Vitro Approaches
Authors: Bai Yongtao , Dai Guoliang , Song Lihua , Gu Xiaolei , Ba Ning , Ju Wenzheng , Zhang Wenzhou 
Published: July 2022

Zhi-Zi Hou-Po Decoction (ZHD) has been widely used in the treatment of depression for centuries. This study aimed to investigate the antidepressant effects of the water extract of ZHD (ZHD-WE) and ethanol extract of ZHD (ZHD-EE) using behavioral despair tests in mice, and to further explore the neuroprotective effects in a PC12 cell injury model induced by corticosterone (CORT). Mice were divided into a control group (normal saline), ZHD-WE groups (4, 8, and 16 g kg−1), ZHD-EE groups (4, 8, and 16 g kg−1) and the fluoxetine group (20 mg kg−1). The forced swimming test (FST) and tail suspension test (TST) were used to screen the antidepressant effects of ZHD-WE and ZHD-EE after oral administration for seven consecutive days. The level of brain-derived neurotrophic factor (BDNF) in the hippocampus was determined by ELISA. The MTT, lactate dehydrogenase (LDH) and flow cytometry analysis were performed to elucidate the neuroprotective effect of ZHD-EE on a PC12 cell injury model. Additionally, the mRNA and proteins expression of apoptotic molecules Bax, Bcl-2 and BDNF were detected by RT-PCR and western blot assay. It showed that ZHD-EE at concentrations of 8 and 16 g kg−1 significantly decreased the immobility time in the TST and FST, and increased the BDNF levels in the hippocampus. While ZHD-WE at concentrations of 4, 8, and 16 g kg−1 had no significant effect on the immobility time in the TST, and only the 16 g kg−1 of extract group significantly decreased the immobility time in the FST. In vitro, the obtained results showed that PC12 cells pre-incubated with ZHD-EE at concentrations of 100 and 400 μg ml−1 improved cell viability, decreased LDH release, and reduced apoptosis rate of PC12 cells. Moreover, ZHD-EE significantly increased the mRNA and proteins expression of Bcl-2 and BDNF, while decreased the mRNA and protein expression of Bax. ZHD-EE significantly improved despair-like behavior in mice, and its mechanism may be related to BDNF upregulation in the hippocampus. This study also showed that ZHD-EE had a protective effect on CORT-induced injury in PC12 cells by upregulating the expression of BDNF and restoring Bcl-2/Bax balance.
Post-Activation Performance Enhancement: Save Time With Active Intra-Complex Recovery Intervals
Authors: Trybulski Robert , Makar Piotr , Alexe Dan Iulian , Stanciu Silvius , Piwowar Rafał , Wilk Michal , Krzysztofik Michal 
Published: July 2022

This study aimed to determine whether the intra-complex active recovery within the strength-power potentiating complex will impact the upper-body post-activation performance enhancement effect and how the magnitude of this effect will change across the upper-body complex training session. Thirteen resistance-trained males [the age, body mass, height, experience in resistance training, and one-repetition maximum (1RM) in bench press were 27 ± 4 years; 92.3 ± 15.4 kg; 182 ± 6 cm; 6.4 ± 2.4 years, and 118 ± 29 kg, respectively) participated in this study. Each participant completed a baseline bench press throw performance assessment at 30% 1RM. Next, five strength-power potentiating complexes consisting of a bench press at 80% 1RM were tested until the average barbell velocity decreased by 10% as a conditioning activity, and 6 min later, a re-test of bench press throw was carried out. During one experimental session during the rest interval inside the complex, they performed swiss ball leg curls, while between the complexes, a plank exercise (PAP-A) was performed. During the second experimental session, participants performed no exercises within the strength-power potentiating complexes and between them (PAP). Under control conditions, participants ran the same protocol (as the PAP condition) without the conditioning activity (CTRL). Friedman’s test showed significant differences in peak (test = 90.634; p &lt; 0.0001; Kendall’s W = 0.410) and average (test = 74.172; p &lt; 0.0001; Kendall’s W = 0.336) barbell velocities during bench press throw. Pairwise comparisons indicated that the peak and average barbell velocities significantly increased in the fourth set [p = 0.022, effect size (ES) = 0.76 and p = 0.013, ES = 0.69, respectively], and the average barbell velocity was also increased in the second set (p = 0.018, ES = 0.77) in comparison to the baseline value during the PAP-A condition. Moreover, the peak barbell velocity was increased in the second (p = 0.008, ES = 0.72) and third (p = 0.019, ES = 0.76) sets compared to the baseline value during the PAP condition. This study showed that body-weight lower-body exercise as an intra-complex active recovery did not impair the upper-body post-activation performance enhancement effect across the complex training session.
Usage Patterns of Telepsychology and Face-to-Face Psychotherapy: Clients’ Profiles and Perceptions
Authors: Sora Beatriz , Nieto Rubén , Montesano Adrian , Armayones Manuel 
Published: July 2022

BackgroundCurrently, most people who might need mental health care services do not receive them due to a number of reasons. Many of these reasons can be overcome by telepsychology, in other words, the use of ICT technologies for therapy (e.g., phone, videoconferencing, and apps); given that it facilitates access to specialized interventions. In fact, telepsychology is currently offered as an active service in many psychotherapy centers. However, its usage, how it is perceived, and who uses it are still largely unknown.ObjectiveThe aim of this study was (1) to determine if any pattern exists in the usage of telepsychology and face-to-face psychology, (2) to clarify people’s perception of telepsychology in terms of the advantages, barriers and efficacy of online psychotherapy, and (3) to examine usage patterns in terms of individual characteristics and identify patients’ profiles.MethodsAn online survey was conducted on a convenience sample of 514 subjects recluted by using an online advertisement. The inclusion criteria were: (1) to be older than 18 years old and (2) to answer completely the questionnaire. Cluster analysis, ANOVAs, and discriminant analysis were performed to test our research objectives.ResultsThree usage clusters were found: (1) face-to-face psychotherapy (57%; n = 292); (2) non-therapy (36.8%; n = 189); and (3) combined face-to-face psychotherapy and telepsychology (6.4%; n = 33). In addition, the perception of telepsychology varied among usage clusters, but a common perception emerged about the main telepsychology advantages, barriers and efficacy. Finally, the results showed that personal characteristics differentiated people in each of these clusters.ConclusionThe most common form of access to psychotherapy is the face-to-face form but the second way of delivery was a combination between face to face and online psychotherapy (research objective 1). People who combine face to face with online psychotherapy perceives this last as more efficient and with less barriers to access (research objective 2). Finally, some characteristic as eHealth experience and sociodemographic variables can help to identify people that will attend telepsychology initiatives (research objective 3). These clusters provide insight into opportunities for face-to-face and online patient engagement strategies.
Association of Fatigue With Sleep Duration and Bedtime During the Third Trimester
Authors: Ma Duo , Kang Yimin , Wang Denglan , Chen Haoxiong , Shan Ligang , Song Chun , Liu Yanlong , Wang Fan , Li Hui 
Published: July 2022

PurposeTo investigate the association between fatigue and sleep habits of pregnant women to further explore the effect of sleep duration and bedtime on fatigue during the third trimester.Materials and MethodsA total of 465 Chinese Han pregnant women in the third trimester (after 28 weeks) with a singleton gestation were recruited. Sleep habits (such as bedtime, sleep onset latency, and night sleep duration) and the 14-item Fatigue Scale scores (FS-14, used to assess fatigue) were collected.ResultsThe effects of sleep duration and bedtime on FS-14 physical and total scores were significant. FS-14 physical scores and total scores of the participants in the group of sleep before 23 o’clock (SBC) of short sleep duration (&lt;7 h) were significantly higher as compared to the participants in the group of SBC of normal sleep duration, and those of the participants in the group of SBC of normal sleep duration were significantly lower than the participants in the group of sleep after 23 o’clock of normal sleep duration. There were negative correlations of sleep duration with FS-14 physical score and total score in the SBC of short sleep duration group.ConclusionSleep less than 7 h or bedtime after 23 o’clock was associated with increased fatigue levels of pregnant women in the third trimester. Therefore, it is necessary to develop good sleep habits (enough sleep duration and early bedtime) to keep fatigue at a low level for pregnant women in the third trimester.
Disease Characteristics, Care-Seeking Behavior, and Outcomes Associated With the Use of AYUSH-64 in COVID-19 Patients in Home Isolation in India: A Community-Based Cross-Sectional Analysis
Authors: Srikanth Narayanam , Kumar Adarsh , Chandrasekhararao Bhogavalli , Singhal Richa , Yadav Babita , Khanduri Shruti , Jameela Sophia , Rai Amit Kumar , Tripathi Arunabh , Rana Rakesh , Ahmad Azeem , Sharma Bhagwan Sahai , Jaiswal Ankit , Kotecha Rajesh ,   State Level Collaborators
Published: July 2022

BackgroundDuring the second wave of the COVID-19 pandemic in India, the Ministry of Ayush conducted a community study to provide therapeutic care to patients with asymptomatic, mild, and moderate COVID-19 in home isolation based on the empirical evidence generated on the efficacy of AYUSH-64 in COVID-19.ObjectiveTo document disease characteristics, care-seeking behavior, and outcomes in patients with asymptomatic, mild, or moderate COVID-19 in home isolation who used AYUSH-64 for COVID-19.MethodsCross-sectional analysis of the data generated through a community study conducted in India from 08 May to 31 August 2021 was performed to study the disease characteristics, care-seeking behavior during home isolation, clinical outcomes, adverse events, and the association between various risk factors and clinical recovery during the study period. The data were collected through semi-structured questionnaires, available in electronic data collection format at the baseline, 7, 14, and 21 days. A logistic regression was performed to explore the relationship between relevant variables and clinical recovery.ResultsData from 64,642 participants were analyzed for baseline assessment, and final analysis was done for 49,770 participants. The mean age of the enrolled participants was 38.8 ± 11.7 years, and 8.4% had co-morbidities. AYUSH-64 was utilized as an add-on to the standard care by 58.3% of participants. Comparable clinical outcomes were observed in participants utilizing AYUSH-64 either as a standalone or as an add-on to standard care, in terms of clinical recovery, disease progression, the requirement for oxygen supplementation, hospitalization, ICU admission, and need for ventilator support. Younger age, having no co-morbidities or substance abuse, and having been vaccinated were associated with early clinical recovery than those who were older and not vaccinated.ConclusionsThe study findings suggest that AYUSH-64 use, either standalone or as an adjunct to standard care, in asymptomatic, mild, or moderate COVID-19 is associated with good clinical outcomes. Ayush services and interventions can be effectively integrated into the mainstream public health architecture to serve public health goals.
Exploring the Multidimensionality of Trust in Participatory Health Partnerships - A Network Approach
Authors: Gilfoyle Meghan , Salsberg Jon , McCarthy Miriam , MacFarlane Anne , MacCarron Pádraig 
Published: July 2022

IntroductionPrevious studies have identified “trust” as a key mechanism to achieve sustainable partnerships in participatory health research, which themselves can represent social networks. A recent review discussed the potential for social network analysis to investigate the development and maintenance of trust and its effects on partnership functioning in participatory health research partnerships. This review also recommended considering a comprehensive, nuanced and multidimensional approach to conceptualizing, operationalizing and measuring trust in research partnerships. Thus, this study aims to explore empirically the conceptualizing, operationalizing and measuring of trust in a multidimensional manner, approaching each trust dimension as an individual trust network, as well as combined as an overall trust network.MethodsWe sampled the whole network, recruiting from a newly established network of 57 individuals that must collaborate to achieve a common goal. These individuals represented academic, service and community organizations of an existing participatory partnership, the Public and Patient Involvement Ignite Network in Ireland. Of the 57 individuals invited to take part in the study, 75% (n = 43) individuals completed the network survey. A survey about trust was designed based on literature in the area and was administered via Qualtrics. The survey included eight network questions: one on collaboration, and seven on specific dimensions of trust. From this, we constructed a network for each trust dimension. We compared several core network measures of each to identify structural differences between the dimensions of trust. To statistically validate them, we compared them to a random and preferential null model.ResultsAll the networks had a high reciprocity but were decentralized. Key differences were identified across trust dimensions, particularly in terms of integrity and shared values, visions and goals. None of the networks compared well to the null models indicating participants did not randomly or preferentially (based on how much trust they receive for a particular trust dimension) trust other partners.Discussion/ConclusionThis novel empirical social network analysis of trust in a real-world partnership elucidates the nuances and multidimensional nature of trust. This provides support for expanding this research direction to enhance understanding of and interventions for trust in participatory health research.
Investigating Affective Responses to Remotely Delivered “At Home” Low Volume High Intensity Interval Exercise: A Non-Randomized Parallel Group Feasibility Study
Authors: Howard Imogen , Niven Ailsa , Kelly Paul , Phillips Shaun M. 
Published: July 2022

BackgroundLow volume-high intensity interval exercise (LV-HIIE) has gained interest, due to its efficiency in invoking health and fitness benefits. However, little research has studied “at home” feasibility or effects of LV-HIIE. This study aimed to demonstrate that remote “at-home” LV-HIIE research is possible and to investigate if affective responses to the LV-HIIE protocol, subsequent intentions, and self-efficacy to repeat were related to self-reported tolerance of the intensity of exercise.MethodsUsing self-reported tolerance of the intensity of exercise, 41 healthy, physically active participants (25 female and 16 male; age 21.3 ± 1.0 years, body mass index 23.0 ± 2.9 kg.m2) were divided into low tolerance (LT, n = 14), middle tolerance (MT, n = 15), and high tolerance (HT, n = 12) groups. Participants completed a 20-min LV-HIIE circuit training video [2 × (10 ×30 s work, 15 s rest)] at home. Participants reported ratings of perceived exertion, affective valence, and perceived activation at baseline, during the protocol, immediately post-protocol, and during the cool down. 20-min after completion, respondents answered questions on exercise task self-efficacy and intentions to repeat LV-HIIE.ResultsThe study recruited n = 65 individuals, of whom n = 50 passed screening. Ultimately n = 41 (82%) completed the exercise protocol and data collection. Ratings of perceived exertion were not significantly different between groups (p = 0.56), indicating similar perceptions of task difficulty. There was no significant effect of tolerance on affective valence (p = 0.36) or felt arousal (p = 0.06). There was evidence of high individual variability in affective responses within and between participants. Subsequent intentions and self-efficacy to repeat the exercise protocol did not seem to be related to affective valence during or after the protocol.DiscussionRecruitment and data collection indicated that research into “at home” LV-HIIE is possible. High individual differences in affective responses suggest that LV-HEII may be appropriate for some but not all as an exercise option. Assessing self-reported tolerance of intensity of exercise may not appropriately identify whether or not LV-HIIE will be suitable for an individual.
Assessing Textbook Outcome After Implementation of Transversus Abdominis Release in a Regional Hospital
Authors: Wegdam Johannes A. , de Jong Dite L. C. , de Vries Reilingh Tammo S. , Schipper Ellis E. , Bouvy Nicole D. , Nienhuijs Simon W. 
Published: July 2022

Background: The posterior component separation technique with transversus abdominis release (TAR) was introduced in 2012 as an alternative to the classic anterior component separation technique (Ramirez). This study describes outcome and learning curve of TAR, five years after implementation of this new technique in a regional hospital in the Netherlands.Methods: A standardized work up protocol, based on the Plan-Do-Check-Act cycle, was used to implement the TAR. The TAR technique as described by Novitsky was performed. After each 20 procedures, outcome parameters were evaluated and new quality measurements implemented. Primary outcome measure was Textbook Outcome, the rate of patients with an uneventful clinical postoperative course after TAR. Textbook Outcome is defined by a maximum of 7 days hospitalization without any complication (wound or systemic), reoperation or readmittance, within the first 90 postoperative days, and without a recurrence during follow up. The number of patients with a Textbook Outcome compared to the total number of consecutively performed TARs is depicted as the institutional learning curve. Secondary outcome measures were the details and incidences of the surgical site and systemic complications within 90 days, as well as long-term recurrences.Results: From 2016, sixty-nine consecutive patients underwent a TAR. Textbook Outcome was 35% and the institutional learning curve did not flatten after 69 procedures. Systemic complications occurred in 48%, wound complications in 41%, and recurrences in 4%. Separate analyses of three successive cohorts of each 20 TARs demonstrated that both Textbook Outcome (10%, 30% and 55%, respectively) and the rate of surgical site events (45%, 15%, and 10%) significantly (p &lt; 0.05) improved with more experience.Conclusion: Implementation of the open transversus abdominis release demonstrated that outcome was positively correlated to an increasing number of TARs performed. TAR has a long learning curve, only partially determined by the technical aspects of the operation. Implementation of the TAR requires a solid plan. Building, and maintaining, an adequate setting for patients with complex ventral hernias is the real challenge and driving force to improve outcome.
Kawin Paksa Dan Implikasinya; Studi Kasus Di Desa Bugo Kabupaten Jepara
Authors: Toriqudin Ahmad Miftakhul 
Published: July 2022

This study was carried out starting from the facts on the ground related to the practice of forced marriage in the village of Bugo Jepara that befell Zubaidah and Mauidloh Hasanah. This fact is based on the existence of ijbar rights for a guardian in marrying women under his guardianship. This type of study is field qualitative, with the aim of finding answers regarding the nature of forced marriage and its implications for the family. The results of this study can be stated that the practice of forced marriage due to the guardian's ijbar rights against Zubaidah is classified in a low sakinah mawaddah wa rahmah marriage because it has more harm than benefits, while Mauidlhoh Hasanah is classified in a moderate sakinah mawaddah wa rahmah marriage even though the benefits are more rather than the harm, but there is an element of coercion in the beginning, there is an unequal fulfillment of rights and obligations.Kajian ini dilakukan berangkat dari adanya fakta di lapangan terkait praktik kawin paksa di desa Bugo Jepara yang menimpa Zubaidah dan Mauidloh Hasanah. Fakta tersebut dilandasi adanya hak ijbar bagi seorang wali dalam menikahkan perempuan yang dibawah kewaliannya. Jenis kajian ini adalah kualitatif lapangan, dengan tujuan untuk menemukan jawaban terkait hakekat kawin paksa dan implikasinya terhadap keluarga. Hasil dari kajian ini dapat dinyatakan bahwa praktik kawin paksa karena adanya hak ijbar wali terhadap Zubaidah tergolong dalam perkawinan yang sakinah mawadah wa rahmah rendah karena lebih banyak mudaratnya ketimbang maslahatnya, sedangkan pada Mauidlhoh Hasanah tergolong dalam perkawinan yang sakinah mawadah wa rahmah sedang meski maslahatnya lebih banyak ketimbang mudaratnya, tapi ada unsur keterpaksaan pada mulanya, ada pemenuhan hak dan kewajiban yang tidak seimbang.
DEVELOPMENT OF INFORMATION SERVICES FOR MONITORING THE PUBLICATION ACTIVITY OF EMPLOYEES OF A SCIENTIFIC ORGANIZATION
Authors: БАКАНОВА Н.Б. 
Published: July 2022

Освещаются вопросы создания информационных сервисов для проведения мониторинга публикационной активности сотрудников научной организации, отражающей результативность научных исследований. Рассматриваются проблемы накопления данных о публикациях сотрудников, размещения данных в информационной базе для их исследования на основе наукометрических показателей.
The article is devoted to the creation of information services for monitoring the publication activity of employees of a scientific organization, reflecting the effectiveness of scientific research. The article deals with the problems of accumulating data on publications of employees, reflecting data in the information base for the study of these data based on scientometric indicators.
ANALISIS PEMBAGIAN HARTA BERSAMA AKIBAT PERCERAIAN DI PENGADILAN AGAMA KELAS IA TANJUNG KARANG (Studi Perkara Nomor: 1085/Pdt.G/2013/PA.Tnk)
Authors: Susilawati Susilawati , Rohani Rohani , Indra Karsa Topan 
Published: July 2022

Penelitian ini bertujuan untuk memahami bagaimana cara pembagian harta bersama setelah terjadinya perceraian di Pengadilan Agama Kelas IA Tanjung Karang dalam perkara Nomor: 1085/Pdt.G/2013/PA.Tnk?, Apakah yang menjadi hambatan dalam pembagian harta bersama akibat perceraian di Pengadilan Agama Kelas IA Tanjung Karang dalam perkara Nomor: 1085/Pdt.G/2013/PA.Tnk? Pendekatan penelitian yang digunakan dalam penelitian ini adalah melalui pendekatan yuridis normatif dan pendekatan empiris dengan menggunakan data sekunder dan data primer, selanjutnya dilakukan analisis data secara deskriptif kualitatif. Berdasarkan hasil penelitian bahwa cara pembagian harta bersama akibat perceraian di Pengadilan Agama Kelas IA Tanjung Karang dalam Perkara Nomor: 1085/Pdt.G/2013/PA.Tnk sudah cukup baik dalam pelaksanaannya yakni harta bersama/harta gono-gini dibagi 2 (dua) antara pihak suami dan pihak isteri pasca perceraian. Hambatan dalam pembagian harta bersama akibat perceraian di Pengadilan Agama Kelas IA Tanjung Karang dalam Perkara Nomor: 1085/Pdt.G/ 2013/PA.Tnk antara lain tanggung jawab dari suami isteri yang mempunyai angsuran hutang, tidak adanya itikat baik dan kesadaran hukum dari Tergugat untuk melaksanakan Putusan Pengadilan yang telah memperoleh kekuatan hukum tetap. Jurusita Pengadilan Agama Kelas IA Tanjung Karang harus bertindak secara tegas dalam menegakkan dan melaksanakan putusan yang telah berkekuatan hukum tetap.
Kata Kunci: Pembagian, Harta Bersama, Perceraian