bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gamma Knife radiosurgery for metastatic brain tumors from ovarian cancer: histopathological analysis of survival and local control. A Japanese multi-institutional cooperative and retrospective cohort study
Authors: Matsunaga Shigeo , Shuto Takashi , Serizawa Toru , Aoyagi Kyoko , Hasegawa Toshinori , Kawagishi Jun , Yomo Shoji , Kenai Hiroyuki , Nakazaki Kiyoshi , Moriki Akihito , Iwai Yoshiyasu , Yamamoto Tetsuya 
Published: February 2022

OBJECTIVE
Brain metastasis is rare in ovarian cancer patients. The results of Gamma Knife radiosurgery (GKRS) for the treatment of patients with brain metastases from ovarian cancer were retrospectively analyzed to derive the efficacy and prognostic factors for survival and local tumor control. Further histopathological analysis was also performed.

METHODS
The authors retrospectively reviewed the medical records of 118 patients with 566 tumors who had undergone GKRS at the 10 GKRS institutions in Japan.

RESULTS
After the initial GKRS, the median overall survival time was 18.1 months. Multivariate analysis showed that uncontrolled primary cancer (p = 0.003) and multiple intracranial metastases (p = 0.034) were significant unfavorable factors. Ten patients died of uncontrolled brain metastases at a median of 17.1 months. The 6-, 12-, and 24-month neurological death rates were 3.2%, 4.6%, and 11.9%, respectively. The 6-, 12-, and 24-month neurological deterioration rates were 7.2%, 13.5%, and 31.4%, respectively. The 6-, 12-, and 24-month distant brain control failure rates were 20.6%, 40.2%, and 42.3%, respectively. Median tumor volume was 1.6 cm3 and marginal dose was 20 Gy. The 6-, 12-, and 24-month local tumor control rates were 97.6%, 95.2%, and 88.0%, respectively. Peritumoral edema (p = 0.043), more than 7-cm3 volume (p = 0.021), and prescription dose less than 18 Gy (p = 0.014) were factors that were significantly correlated in local tumor control failure. Eight patients had symptomatic radiation injury. The 6-, 12-, and 24-month GKRS-related complication rates were 3.3%, 7.8%, and 12.2%, respectively. Primary ovarian cancer was histopathologically diagnosed for 313 tumors in 69 patients. Serous adenocarcinoma was found in 37 patients and other types in 32 patients. Median survival times were 32.3 months for the serous type and 17.4 months for other types after initial GKRS. Patients with serous-type tumors survived significantly longer than patients with other types (p = 0.039). The 6-, 12-, and 24-month local tumor control rates were 100%, 98.8%, and 98.8%, respectively. Serous-type tumors were a significantly good prognosis factor for local tumor control after GKRS (p = 0.005).

CONCLUSIONS
This study established a relationship between the efficacy of GKRS treatment for brain metastases and the histological type of primary ovarian cancer. GKRS for ovarian cancer brain metastasis can provide satisfactory survival and local control, especially in cases of serous adenocarcinoma.
C1-ring osteosynthesis versus C1–2 fixation fusion in the treatment of unstable atlas fractures: a multicenter, prospective, randomized controlled study with 5-year follow-up
Authors: Yan Liang , Du Jinpeng , Yang Junsong , He Baorong , Hao Dingjun , Zheng Bolong , Yang Xiaobin , Hui Hua , Liu Tuanjiang , Wang Xiaodong , Guo Hua , Chen Jian , Wang Shaofei , Ma Shengzhong , Dong Shengli 
Published: February 2022

OBJECTIVE
The aim of the present study was to compare the long-term effects of posterior C1-ring osteosynthesis and C1–2 fixation fusion in the treatment of unstable atlas fractures.

METHODS
A multicenter, prospective, randomized controlled trial was conducted to analyze 73 patients with atlas fractures who underwent posterior fixation. The intervention group was treated with C1-ring osteosynthesis, and the control group was treated with C1–2 fixation fusion. The patients were followed up for 6 months, 1 year, 2 years, and 5 years after the operation.

RESULTS
Fifty-two patients had complete data at the last follow-up. The visual analog scale (VAS) score for neck pain in the intervention group was lower than that in the control group (p < 0.001). The operation time, intraoperative blood loss, radiation dose, bedridden period, hospital stay, and cost in the intervention group were significantly lower than those in the control group (p < 0.001). At the last follow-up, the Neck Disability Index in the intervention group was higher than that of the control group, and the angle of flexion-extension and axial rotation in the intervention group were greater than those in the control group (p < 0.001).

CONCLUSIONS
In this study, the authors found that posterior C1-ring osteosynthesis is superior to C1–2 fixation fusion in terms of long-term relief of neck pain and preservation of the physiological function of the cervical vertebrae. This technique is a reliable choice for the treatment of unstable C1 fractures.
Foreword
Authors: Editorial board  
Published: February 2022

Making Archaeology Public. A View from the Mediterranean, Eastern Europe and Beyond
The concept of Public Archaeology has profoundly changed since Mc Grimsey’s first formulation in the early 1970s, as it developed a solid conceptual and practical framework along the years that makes it now an independent branch of archaeology. However, in English-speaking and Northern European countries, the perception of archaeology as a common good was widely spread even before the actual formalization of Public Archaeology as a specific curriculum offered by several universities. Not surprisingly, such an earlier interest led to the development of a markedly North Europe-centric perspective on the topic, which keeps steering much of the current reflection on Public Archaeology despite the emergence of multiple and alternative standpoints on the matter, further deepening the great divide between the archaeologies of Northern and Southern European countries.
Public Archaeology in Greece: A Review of the Current State of the Field
Authors: Sakellariadi Anastasia 
Published: February 2022

As far as archaeology deals with the past in the present, it is already a public endeavour; especially so in southern Europe, where contemporary identities are drawn from ancient cultures, such as the Greek and Roman. In Greece, the political role of the discipline marked antiquities as goods of the people and archaeology as a highly popular discourse. This led to the creation of a state mechanism to manage antiquities for the benefit, but ironically at the exclusion, of the people, in an authoritative top-down approach. In defiance, various actors participate in the public discourse about the past, cultural heritage and its roles today.
This paper will review the state of the field by bringing together research in public archaeology in Greece but also non-academic initiatives, such as NGOs and citizen movements. It is argued that public engagement, primarily through museum exhibitions - the most formal and controlled interface between archaeology and non-archaeologists – and cultural events in archaeological sites, is the primary aspect of public archaeology. While public archaeological discourse is overabundant and expansive though, critical research and analysis are lagging and conventional narratives remain broadly unchallenged.
Association between Smoking and Overall and Specific Mortality in Patients with Bladder Cancer: A Population-based Study
Authors: Ho Chung-Han , Tseng Wen-Hsin , Huang Steven K. , Liu Chien-Liang , Wu Yu-Cih , Chiu Allen W. , Ong Khaa Hoo 
Published: February 2022

BACKGROUND: The role of smoking in the prognosis of bladder cancer may significantly impact clinical management. It is also a considerable burden to Taiwan’s economy and health of its citizens. OBJECTIVE: To search Taiwan’s National Health Insurance Research Database to determine whether smoking affected overall and cancer-specific mortality of patients with bladder cancer. METHODS: We collected data on basic information, tumor stage, and comorbidities. Each smoking case was propensity score-matched by age, sex, and diagnosis year to one control individual among bladder cancer patients. The study comprised a never-smoke and an ever-smoke group, with each group including 4,728 patients after matching. We evaluated the association between smoking and mortalities in patients with bladder cancer. Cox proportional regression modeling was used to estimate hazard ratios (HRs) of overall and cancer-specific mortality rates. Stratified analysis was also performed to estimate risk ratios of overall and cancer-specific mortalities in bladder cancer patients with and without a history of smoking history among different subgroups. RESULTS: The overall and specific mortality ratio of patients who were ever smokers were 1.15-fold and 1.16-fold, respectively, compared with those of never smokers (overall: 95% confidence interval [CI], 1.06–1.26, P = 0.0014; specific: 95% CI, 1.03–1. 03, P = 0.0176). Patients with bladder cancer who smoked and had significantly higher overall and specific mortality rates were those with Charlson Comorbidity Index (CCI)≥3 (overall: P = 0.0119; specific: P = 0.0092), diabetes mellitus (DM; overall: P = 0.0046; specific: P = 0.0419), and non-muscle-invasive bladder cancer (NMIBC; overall: P = 0.0038; specific: P = 0.0014). CONCLUSIONS: Overall and specific mortality rates were significantly higher in the ever-smoke group than in the never-smoke group. The ever-smoke group with male sex, CCI≥3, DM, and NMIBC had increased risks for overall and specific mortality.
Retrograde Procedural Memory in Parkinson’s Disease: A Cross-Sectional, Case-Control Study
Authors: Pauly Laure , Pauly Claire , Hansen Maxime , Schröder Valerie E. , Rauschenberger Armin , Leist Anja K. , Krüger Rejko ,   on behalf of the NCER-PD Consortium
Published: February 2022

Background: The analysis of the procedural memory is particularly relevant in neurodegenerative disorders like Parkinson’s disease, due to the central role of the basal ganglia in procedural memory. It has been shown that anterograde procedural memory, the ability to learn a new skill, is impaired in Parkinson’s disease. However, retrograde procedural memory, the long-term retention and execution of skills learned in earlier life stages, has not yet been systematically investigated in Parkinson’s disease. Objective: This study aims to investigate retrograde procedural memory in people with Parkinson’s disease. We hypothesized that retrograde procedural memory is impaired in people with Parkinson’s disease compared to an age- and gender-matched control group. Methods: First, we developed the CUPRO evaluation system, an extended evaluation system based on the Cube Copying Test, to distinguish the cube copying procedure, representing functioning of retrograde procedural memory, and the final result, representing the visuo-constructive abilities. Development of the evaluation system included tests of discriminant validity. Results: Comparing people with typical Parkinson’s disease ( n = 201) with age- and gender-matched control subjects ( n = 201), we identified cube copying performance to be significantly impaired in people with Parkinson’s disease ( p = 0.008). No significant correlation was observed between retrograde procedural memory and disease duration. Conclusion: We demonstrated lower cube copying performance in people with Parkinson’s disease compared to control subjects, which suggests an impaired functioning of retrograde procedural memory in Parkinson’s disease.
DAYA TERIMA BARUASA SUBTITUSI TEPUNG KULIT PISANG
Authors: Wati HJ.Sukma , Nadimin Nadimin , Suria Suria 
Published: February 2022

Background: Baruasa is favored the local snacks by the people of South Sulawesi, but low in fiber. One of the high fiber foods is the banana hump. Banana hump can be processed into semi-finished materials such as banana hump flour. Banana hump flour can be substituted on the manufacture of baruasa.Objective: The purposeof this study to determine how the effect of banana hump flour substitution on the power of the baruasa receipt. This research is pre experimental research that is making baruasa with three varieties of banana hump flour substitution (10%, 20% and 30%). Hedonic test using untrained panelists are Nutrition Students of Poltekkes Makassar as many as 35 people. Analysis of hedonic test data using Anova and Tukey test with SPSS program.Results: The results showed that the preferred formula of the panelis of the color aspect is F1 of 82.85%, the smell is F1 of 88.57%, the texture of F1 is 54.29% and the sense is F1 of 80% .The test results show that there is a difference of panelist acceptance of the color aspect, Flavor and smell of banana hump flour subtitution flour with p <α value (0,05), whereas in texture aspect there is no difference of acceptance of baruasa banana hump flour with p> α (0,05).Conclusion: It was concluded that the higher concentration of banana hump flour addition was lower due to the panelist's preference for the acceptable power.Suggestion: It is recommended for further preparation, it is better to do further research on how to reduce the color of browning, as well as the smell and flavor of the banana hump flour which is rather sharp on the baruasa.Keywords: Baruasa, Banana Hump Flour, Acceptability
GAMBARAN PENGETAHUAN GIZI DAN POLA MAKAN PASIEN RAWAT JALAN DIABETES MELLITUS TIPE-2 DI RUMAH SAKIT
Authors: Tamrin Abdullah , Rowa Sitti Sahariah , Chaerunnimah Chaerunnimah , Irwansyah M 
Published: February 2022

Background: Knowledge of nutrition is the ability to understand the concepts and principles as well as information related to nutrition. Provincial health profile data south sulawesi in 2015, Diabetes Mellitus outpatients aged 40 years and above is 85%. Data on the record medic general hospital the area of a city makassar be seen that of diabetes mellitus in 2015 were 234 men and women 165.Objective: This research aims to describe the knowledge about nutrition and food consumption pattern among outpatients diabetes mellitus tipe-2 ( dm tipe-2 ) in a public hospital the area of a city Makassar.Method: Sampling done by purposive sampling criteria of Diabetes Mellitus patients visiting the hospital in June 2016 and suffered no complications.Result: The results of this study are patients with good nutritional knowledge are 48.6% and patients who have less nutritional knowledge are 51.4%. Patients who have food consumption pattern based on the frequency of good food is 42.9 % and 57.1% have less. Food consumption pattern based on the composition dishes of food in general is good which is 100%. Conclusion: Conclusions from this research is their knowledge about nutrition generally still less that is 51,4 % .Food consumption pattern based on the frequency of food is generally less that is 57.1 % , Food consumption pattern based on the composition dishes of food in general is good which is 100% and a %. Food consumption pattern based on a kind of food is generally good but lacking in fruits.Suggest: For side Hospital so that to schedule it illumination to patient Diabetes Mellitus about its important various of fruit to patient Diabetes Type Mellitus-2.Key Word : Nutrient Knowledge, eating Pattern, Patient Take care Way,Type DM-2
Perkinsus Infections of Bivalve Molluscs
Authors: Petty Denise 
Published: February 2022

FA178, a 6-page fact sheet by Denise Petty, describes the infections caused by this group of protistan parasites that can infect shellfish — signs of infection in molluscs, life cycle, transmission, diagnosis, regulatory concerns, treatment and disinfection of facilities, and food safety. Includes references and glossary. Published by the UF Department of School of Forest Resources and Conservation, November 2010.
2010 PDF version unavailable, 2013 version included instead.
Seafood Perceptions among People Aged 55 and Above: Summary of Focus Groups Results
Authors: Wysocki Allen F. , House Lisa , Messina William A. 
Published: February 2022

FE821, a 5-page fact sheet by Allen F. Wysocki, Lisa House, and William A. Messina, Jr., provides a brief summary of the focus group part of a study of perceptions of Florida residents aged 55 and over on seafood consumption. Published by the UF Department of Food and Resource Economics, November 2009. Reviewed March 2013.
FE821/FE821: Seafood Perceptions among People Aged 55 and Above: Summary of Focus Groups Results (ufl.edu)
Biztonságtudatosság – hazai helyzetkép, hazai gyakorlat és példák 1.
Authors: Mezei József , Koncz Veronika , Jasenszky Nándor 
Published: February 2022

A 21. század elején számos olyan esemény és változás történt a világban, amely jelentős hatást gyakorolt a titkosszolgálatok tevékenységére is. Ezek közül kiemelkednek a nyugati társadalmakat sokkoló terrorcselekmények az Amerikai Egyesült Államokban és Európában, az információtechnológia rohamos fejlődése, valamint ezzel együtt, az ezzel kölcsönhatásban álló információrobbanás. Ezen tényezők egyik következménye lett a biztonságtudatosító programok rendszerszintű megjelenése a nemzetbiztonság területén például a terrorelhárítással és az információvédelemmel összefüggésben. E két részből álló publikáció célja, hogy bemutassa a magyar titkosszolgálatok, illetve a Terrorelhárítási Központ által aktuálisan folytatott ilyen típusú programokat. A publikáció a Nemzeti Közszolgálati Egyetem Nemzetbiztonsági Intézete által folytatott ez irányú kutatás részeként került összeállításra azzal a céllal, hogy a kutatásban kiindulási alapot biztosítson a nemzetközi példákat is figyelembe vevő, a hazai programok eredményességét elősegíteni kívánó módszertani ajánlásokhoz.
GAMBARAN PENGETAHUAN REMAJA MENGENAI SEKSUAL PRANIKAH DI SMA "X” KOTA BOGOR TAHUN 2021
Authors: Nur Khotimah Risma , Masitha Arsyati Asri , Saputra Nasution Ade 
Published: February 2022

Masa remaja merupakan suatu periode transisi antara masa kanak-kanak menuju dewasa yang ditandai dengan kematangan fisik, kognitif, sosial, dan emosional. Berdasarkan data World Health Organization (WHO) menunjukkan sekitar 40% remaja umur 18 tahun telah melakukan hubungan seks meskipun tanpa ada ikatan pernikahan dibeberapa Negara berkembang. Penelitian ini menggunakan kuantitatif desain studi descrption dengan analisis univariat. Populasi berjumlah 319 siswa dengan sampel penelitian sebanyak 80 responden.Hasil penelitian menunjukkan sebanyak 23.8% (19 orang) responden memiliki Perilaku Seksual pranikah, dan sebanyak 76.3% (61 orang) responden tidak memiliki perilaku seksual pranikah sebanyak 21.3% (17 orang) responden memiliki tingkat pengetahuan kurang, dan sebanyak 78.8% (63 orang) responden memiliki tingkat pengetahuan baik. Maka diharapkan orang tua dan guru untuk memberikan bimbingan dan konseling yang mengharuskan remaja agar dapat meningkatkan pengetahuan mengenai kesehatan reproduksi guna mencegah terjadinya perilaku remaja yang menyimpang.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN HIPERTENSI PADA PRA LANSIA DI PUSKESMAS BOJONGGEDE TAHUN 2021
Authors: Oktaviani Elsa , Noor Prastia Tika , Dwimawati Eny 
Published: February 2022

Hipertensi atau penyakit tekanan darah tinggi merupakan suatu keadaan peningkatan tekanan darah yang abnormal di dalam arteri yang menyebabkan suatu gangguan pada pembuluh darah yang dapat menimbulkan kerusakan lebih lanjut pada organ tubuh. Tujuan dari penelitian ini yaitu untuk menganalisis hubungan antara aktivitas fisik, merokok, dan tingkat stres dengan hipertensi pada pra lansia di Puskesmas Bojonggede. Jenis metode penelitian yang digunakan yaitu penelitian kuantitatif dengan pendekatan cross sectional. Jumlah sampel dalam penelitian ini sebanyak 87 responden dan didapatkan sampel aktual berjumlah 90 responden dengan teknik pengambilan sampling yaitu purposive sampling. Instrumen penelitian yang digunakan adalah lembar kuesioner FFQ, IPAQ, Indeks Brinkman, dan DASS 42. Analisis data yang digunakan yaitu analisis univariat dan bivariat (chi-square test). Hasil penelitian menunjukkan bahwa terdapat hubungan yang bermakna antara aktivitas fisik (p-value = 0,014), merokok (p-value = 0,002), dan tingkat stres (p-value = 0,012) dengan kejadian hipertensi pada pra lansia. Hal yang dapat dilakukan oleh masyarakat pada usia pra lansia adalah dengan melakukan aktivitas fisik (olahraga) secara teratur, mengurangi bahkan menghentikan perilaku merokok serta mengendalikan stres.
Pectin from Duckweed (Lemnaceae) As Potential Commercial Pectin and Its Gelling Function in Food Production: A Review
Authors: Hanis Nadia Yahya  , Nazariyah Yahaya  , Kamilah Huda Baihagi  , Norlelawati Ariffin  , Yahya Hafiza 
Published: February 2022

Duckweed, a small flowering plant which comes from Lemnaceae family, has been rising in popularity to many researches and applications for its numerous valuable functional properties. One of its special features is fast growing plant and easily adapted to various types of regions which makes it attractive to be manipulated in many applications including in biofuel production, waste water treatment and also for pharmaceutical and medicinal purposes. Pectin is the common component found in plant cell wall and it has been used as food additive for its capability to gel, emulsify and stabilize food products. Several requirements for commercial pectin such as galacturonic acid content (GalA) and degree of amidation have been regulated. Studies have proven that duckweed have significant amount of pectin which make it as a potential source of gelling agent in food industry. However, the structural properties of pectin from duckweed need to be investigated, in order to ensure if they meet the regulated requirements for industrial production. It is also to determine the suitability of duckweed pectin utilization in different type of food products since pectin of different sources have different structural characteristics, thus exhibit different gelling capability. This present review discusses on the potential of pectin from duckweed species to be utilized as food additive with gelling function in food products. Several extraction methods also have been reviewed, which each of them showed different efficiency and affect the extracted pectin characteristics.
Norm attaining multilinear forms on the spaces $c_0$ or $l_1$
Authors: Kim Sung Guen 
Published: February 2022

T∈L(nE)T∈L(nE) is called a norming attaining if there are x1,…,xn∈Ex1,…,xn∈E such that ∥x1∥=⋯=∥xn∥=1‖x1‖=⋯=‖xn‖=1 and |T(x1,…,xn)|=∥T∥,|T(x1,…,xn)|=‖T‖, where L(nE)L(nE) denotes the space of all continuous nn-linear forms on E.E. We investigate norm attaining multilinear forms on c0c0 or l1.l1.
La planificación en la producción y su incidencia en la optimización de los procesos
Authors: Soto Chávez Luis Enrique , Ugalde Vicuña José William 
Published: February 2022

Las organizaciones actualmente batallan a diario para subsistir en el tiempo, adaptándose a las nuevas tendencias de herramientas administrativas y de la tecnología, tratando de conseguir los objetivos planeados y por ende, conseguir tanto como el crecimiento económico como organizacional, con el fin de mantener los estándares máximos de producción que conlleven al logro de esos objetivos, para ello deben entonces, optimizar cada uno de los procesos que se llevan a cabo y que de manera directa o indirecta se relacionan con el proceso de producción, el cual representa uno de los más importantes de toda organización, puesto que es a través de este que se generan los bienes o servicios que se ofrecerán a los consumidores y que por supuesto, son los que generan el ingreso. De allí a que constantemente las organizaciones se esfuerzan en buscar y aplicar distintas técnicas que le permitan asegurar el buen funcionamiento de todos los procesos, representando la planificación un proceso medular, que permite definir cada uno de los pasos que se lleven a cabo para alcanzar las metas, así como también prevenir la detección de problemas o defectos que se presenten, a fin de corregirlos a tiempo y lograr contrarrestar cualquier contratiempo.