bluuebunny/crossref_metadata_2025_split huggingface dataset:
Online graph learning for time‐varying graphs
Authors: Si Binqiang , Luo Dongqi , Zhu Jihong 
Published: June 2022

AbstractIn this paper, the is focus on the online graph learning problems in time‐varying environment. Traditional graph learning methods always assume that the underlying graph is static and that enough training data are available. However, in many real world applications, the underlying graph always changes slowly and only a small batch of data can be accessed at each time step. Under the assumption that the variation of the adjacency matrix is smooth, an online graph learning method is proposed, which improves the performance by leveraging the prior from the previous estimations. Experiments show that the proposed method performs best in both dynamic and static settings.
Ungewöhnliche „Ulkusblutung“ im Magen
Authors: Rabenstein Thomas , Dippold Joachim , Rümenapf Gerhard 
Published: June 2022

ZusammenfassungBei einer Notfall-Endoskopie eines 45-jährigen Mannes mit einer komplizierten medizinischen Vorgeschichte wurde im Magenkorpus ein kleines Ulkus in einer ca. 4 cm durchmessenden, halbkugeligen Impression gefunden. Wir entschlossen uns zu einer sofortigen Durchführung einer Angio-CT-Untersuchung von Abdomen und Thorax. Impression und Ulkus wurden durch ein teilthrombosiertes Aneurysma der Arteria lienalis verursacht. Dieses wurde sofort angiografisch mittels perkutaner transluminaler Implantation eines gecoverten Stents ausgeschaltet. Der Patient erholte sich und konnte nach 12 Tagen aus dem Krankenhaus entlassen werden. Eine Literatursuche ergab, dass in solchen Fällen der sofortige Wechsel von Endoskopie zu einem gefäßchirurgischen Eingriff die beste Option darstellt. Endoskopiker müssen die sog. „Herald-Blutung“ als solche erkennen und die weiteren diagnostischen Schritte sofort veranlassen, da eine zweite Blutung meist fatal endet. Dadurch kann die Prognose auf 20–90 % Überleben verbessert werden. Leider fühlten sich in einer aktuellen Umfrage 50 % der Gastroenterologen über diese Tatsache nicht gut informiert und hätten wahrscheinlich nicht die korrekten Entscheidungen getroffen.
Positionspapier zur Befunderhebung von Darmultraschallbefunden bei chronisch entzündlichen Darmerkrankungen
Authors: Kucharzik Torsten , Atreya Raja , Bachmann Oliver , Baumgart Daniel C. , Daebritz Jan , Helwig Ulf , Janschek Johannes , Kienle Peter , Langhorst Jost , Mudter Jonas , Schmidt Carsten , Schreyer Andreas G. , Vieth Michael , Wessling Johannes , Maaser Christian 
Published: June 2022

Zusammenfassung
Hintergrund Zur Diagnosestellung, Erkennung von Erkrankungskomplikationen sowie zur Verlaufskontrolle bei Patienten mit Morbus Crohn und Colitis ulcerosa wird zunehmend der Darmultraschall eingesetzt. Eine systematische Befunderhebung und Dokumentation sind wichtig, um die Qualität der Befunderstellung und die Kommunikation zwischen den Fachgruppen zu verbessern. Das vorliegende Positionspapier beschreibt die Voraussetzungen für eine optimale Befunderhebung des Darmultraschalls bei Patienten mit chronisch-entzündlichen Darmerkrankungen (CED).
Methoden Eine Experten-Konsensusgruppe bestehend aus Gastroenterologen, Radiologen, Pathologen, Kinder- und Jugend-Gastroenterologen und Chirurgen führte eine systematische Literaturrecherche durch. In einem Delphi-Verfahren wurde unter Mitgliedern des Kompetenznetzes Darmerkrankungen und der Deutschen Röntgengesellschaft (DRG) über relevante Kriterien bei der Befunderhebung von Darmultraschallbefunden abgestimmt. Die daraus resultierenden Statements wurden in einer Experten-Konsensusgruppe verabschiedet.
Ergebnis Praxisorientierte Empfehlungen für eine optimale Befunderhebung mit einer standardisierten Terminologie wurden entwickelt. Der Fokus der Erhebung lag auf der Beschreibung der Entzündungsaktivität sowie der Komplikationen bei CED. Minimale Anforderungen für eine standardisierte Befunderhebung wurden definiert.
Zusammenfassung Das vorliegende Manuskript bietet praktische Empfehlungen zur Optimierung und Vereinheitlichung der Befunderhebung bei Darmultraschall-Untersuchungen bei CED.
Perkutaner Vorhofohrverschluss nach Schlaganfall
Authors: Skurk Carsten , Häusler Karl Georg , Endres Matthias , Lewalter Thorsten , Landmesser Ulf 
Published: June 2022

ZUSAMMENFASSUNGDer katheterbasierte Verschluss des linken Vorhofohrs stellt bei Patienten mit Vorhofflimmern, welche nicht für eine Langzeittherapie mit oralen Antikoagulanzien geeignet sind, eine potenzielle Therapieoption zur Reduktion des Schlaganfallrisikos dar. Die Weiterentwicklung der Device- und Implantationstechnik führte in den letzten Jahren zu einer Verbesserung des Sicherheitsprofils der Behandlungsmethode. Das Therapieprinzip wird durch neue Daten unterstützt, die die Wirksamkeit des operativen Verschlusses des linken Vorhofohrs zusätzlich zur Antikoagulation im Rahmen von kardiochirurgischen Eingriffen zeigen. Aktuell wird der katheterbasierte Verschluss des linken Vorhofohres in verschiedenen Patientenpopulationen in randomisierten Studien evaluiert. Die Datenlage, die Einsatzgebiete und randomisierte Studien unter besonderer Berücksichtigung der CLOSURE-AF-Studie sollen in der vorliegenden Übersichtsarbeit diskutiert werden.
Anatomical Step-by-Step Dissection of Complex Skull Base Approaches for Trainees: Surgical Anatomy of the Endoscopic Endonasal Approach to the Sellar and Parasellar Regions
Authors: Agosti Edoardo , Alexander A. Yohan , Leonel Luciano C.P.C. , Van Gompel Jamie J. , Link Michael J. , Pinheiro-Neto Carlos D. , Peris-Celda Maria 
Published: June 2022

Abstract
Introduction Surgery of the sellar and parasellar regions can be challenging due to the complexity of neurovascular relationships. The main goal of this study is to develop an educational resource to help trainees understand the pertinent anatomy and procedural steps of the endoscopic endonasal approaches (EEAs) to the sellar and parasellar regions.
Methods Ten formalin-fixed latex-injected specimens were dissected. Endoscopic endonasal transsphenoidal transsellar, transtuberculum-transplanum, and transcavernous approaches were performed by a neurosurgery trainee, under supervision from the senior authors and a PhD in anatomy with advanced neuroanatomy experience. Dissections were supplemented with representative case applications.
Results Endoscopic endonasal transsphenoidal approaches afford excellent direct access to sellar and parasellar regions. After a wide sphenoidotomy, a limited sellar osteotomy opens the space to sellar region and medial portion of the cavernous sinus. To reach the suprasellar space (infrachiasmatic and suprachiasmatic corridors), a transplanum-prechiasmatic sulcus-transtuberculum adjunct is needed. The transcavernous approach gains access to the contents of the cavernous sinus and both medial (posterior clinoid and interpeduncular cistern) and lateral structures of the retrosellar region.
Conclusion The anatomical understanding and technical skills required to confidently remove skull base lesions with EEAs are traditionally gained after years of specialized training. We comprehensively describe EEAs to sellar and parasellar regions for trainees to build knowledge and improve familiarity with these approaches and facilitate comprehension and learning in both the surgical anatomy laboratory and the operating room.
Discriminative Ability of Lower limb Strength and Power Measures in
Lacrosse Athletes
Authors: Talpey Scott W. , Axtell Robert , Gardner Elizabeth , Maloney Maggie , Newman Thomas , Cordone Jason , O’Grady Mathew 
Published: June 2022

AbstractThe objective of this investigation was to compare isokinetic strength,
countermovement jump and drop jump variables between high-contributors and
low-contributors within NCAA Division I Men’s and Women’s
lacrosse athletes. Men’s (N=36) and Women’s
(N=30) NCAA Division I lacrosse athletes completed strength testing of
the quadriceps and hamstring across three speeds
(60°·s−1,
180°·s−1,
300°·s−1), countermovement and drop
jumps. To determine the discriminative ability of select lower-limb strength and
power characteristics participants were categorized as high-contributors
(Males N=18, age=20.3±0.4 yrs,
height=183.9±5.5 cm,
mass=90.8±5.8 kg; Females N=15,
age=20.8±0.8 yrs,
height=169.3±6.7 cm,
mass=64.1±7.2 kg) or low-contributors (Males
N=18, age=19.5±0.2 yrs,
height=184.1±5.6 cm;
mass=87.9±8.1 kg; Females N=15,
age=19.7±0.2 yrs,
height=169.8±7.0 cm,
mass=62.9±7.7 kg ) based upon the number of
games the participants competed in during the regular season. Within the male
cohort, moderate significant (p<0.05) differences were observed between
high-contributors and low-contributors in isokinetic hamstring strength of the
left leg at 300°·s−1 (d=0.69) and
peak power in countermovement jump (d=0.68). Within the
women’s cohort a large (d=0.87) significant difference
(p<0.05) in isokinetic strength of the left hamstring was observed
between high-contributors and low-contributors at
60°·s−1. Hamstring strength and
lower-limb power are important strength measures for lacrosse performance and
should be prioritized in training prescription for lacrosse athletes.
Synthesis of 2,3-Diarylquinoxaline Carboxylic Acids in High-Temperature Water
Authors: Unterlass Miriam M. , Amaya-García Fabián 
Published: June 2022

AbstractAromatic carboxylic acids are prone to decarboxylate in high-temperature water (HTW). While the decarboxylation kinetics of several aromatic carboxylic acids have been explored, studies on their compatibility with organic syntheses in HTW are scarce. Herein, we report the hydrothermal synthesis (HTS) of 2,3-diarylquinoxaline carboxylic acids from 1,2-diarylketones and 3,4-diaminobenzoic acid. A detailed study of the reaction parameters was performed to identify reaction conditions towards minimal decarboxylation. Thirteen 2,3-diarylquinoxaline-6-carboxylic acids are obtained at temperatures between 150–230 °C within 5–30 minutes. The reported conditions feature comparable performance to those of classic syntheses, avoiding volatile organic solvents, strong acids and toxic catalysts. Decarboxylated quinoxalines arise as side products in variable amounts via direct decarboxylation of the 3,4-diaminobenzoic acid. To completely inhibit the decarboxylation, we show that suitable structural analogues of 3,4-diaminobenzoic acid can act as starting compounds. Thus, ester hydrolysis of methyl 3,4-diaminobenzoate and deprotection of di-Boc-protected 3,4-diminobenzoic can be coupled with the HTS of quinoxaline towards quinoxaline carboxylic acids, while fully avoiding decarboxylated side products.
Improving Medication Adherence in Asthma
Authors: Kerr Patrick J. , Brennan Vincent , Mac Hale Elaine , Doyle Frank , Costello Richard W. 
Published: June 2022

AbstractIn little over a generation, the ingenuity of scientists and clinician researchers has developed inhaled medications and pathway-specific biological agents that control the inflammation and physiology of asthma. Unfortunately, whether it is because of cost or difficulty understanding why or how to use inhaled medications, patients often do not take these medications. The consequences of poor treatment adherence, loss of control and exacerbations, are the same as if the condition remained untreated. Furthermore, poor adherence is difficult to detect without direct measurement. Together this means that poor treatment adherence is easily overlooked and, instead of addressing the cause of poor adherence, additional medicines may be prescribed. In other words, poor treatment adherence is a risk for the patient and adds cost to healthcare systems. In this article, we discuss the rationale for and the delivery of successful interventions to improve medication adherence in asthma. We contextualize these interventions by describing the causes of poor treatment adherence and how adherence is assessed. Finally, future perspectives on the design of new interventions are described.
Brand attachment: a review and future research
Authors: Shimul Anwar Sadat 
Published: June 2022

AbstractThis paper conducts an integrative review and provides a synthesisation of key themes in the brand attachment literature. A total of 171 papers were selected and analysed using a framework-based approach. In addition to exploring the theories and frameworks, this review summarises the contexts, antecedents, outcomes, mediators, and moderators of brand attachment. Based on the gaps identified in current studies, directions are provided for future brand attachment research. The review suggests that there are multiple directions in which to take the domain further. Theoretical underpinnings require conceptual clarity and consistency with attachment theory, and the development and validation of research frameworks are essential. Furthermore, the application of contextual measurements and rigorous methodologies is warranted to address the shortcomings of the current literature. The recommendations of this review are expected to facilitate advancements in brand attachment research.
Thermodynamically metastable α-, ε- (or κ-), and γ-Ga2O3: From material growth to device applications
Authors: Biswas Mahitosh , Nishinaka Hiroyuki 
Published: June 2022

Gallium oxide (Ga2O3) has attracted tremendous attention in power electronics and ultraviolet photodetectors because of the large bandgap of 4.9–5.3 eV available to all polymorphs, as well as its high electric breakdown voltage. Recently, there has been increasing research interest in thermodynamically metastable phases such as α-, ε- (or κ-), and γ-Ga2O3, because they are predicted to exhibit superior properties compared with β-Ga2O3, the most stable phase of Ga2O3. For example, α-Ga2O3 (bandgap, Eg = 5.3 eV; expected breakdown field, Ec = ∼10 MV/cm) is expected to be a better potential candidate in power electronics than β-Ga2O3 (Eg = 4.5–4.8 eV; Ec = 8 MV/cm) because of its larger bandgap and higher breakdown field. Because these thermodynamically metastable phases cannot be grown using melt-growth techniques, they are grown heteroepitaxially on foreign substrates. We extensively illustrate the growth of these metastable phases and their alloys by employing various growth techniques and then discuss their doping and electronic properties. Finally, we emphasize their applications in devices, including power devices and solar-blind ultraviolet photodetectors.
Simultaneous improvement of magnetic-field-induced working temperature and mechanical properties in Ni–Mn–In shape memory alloy
Authors: Ma Tianyou , Zhang Kun , Han Binglun , Zhao Lei , Zhao Wenbin , Wang Cheng , Liu Rui , Tian Xiaohua , Tan Changlong 
Published: June 2022

Ni–Mn–In magnetic shape memory alloys, which can be stimulated by an external magnetic field, exhibit a fast response and have aroused wide attention in the field of electro-mechanical actuators. However, the low working temperature and the inherent brittleness severely limit their application scenarios. Here, an effective strategy is proposed to improve the magnetic-field-induced working temperature and mechanical properties in Ni–Mn–In shape memory alloys. We predict that the Ni16Mn12In4 alloy with Pt doping can solve the problems simultaneously through a comprehensive first-principles study. The calculations show that Pt occupying Ni sites can increase the martensitic temperature (TM) and Curie temperature (TC) simultaneously. TM and TC of Ni14Mn12In4Pt2 are predicted to be as high as 440 and 476 K, respectively. This is mainly due to the increased phase stability of the martensite and Pt–Mn bonds having stronger ferromagnetic exchange effects than Ni–Mn bonds after Pt doping. Moreover, according to the increase of B/G and v after Pt doping, it can be concluded that the mechanical properties of the alloy have been improved.
Melting points of water models: Current situation
Authors: Blazquez S. , Vega C. 
Published: June 2022

By using the direct coexistence method, we have calculated the melting points of ice Ih at normal pressure for three recently proposed water models, namely, TIP3P-FB, TIP4P-FB, and TIP4P-D. We obtained Tm = 216 K for TIP3P-FB, Tm = 242 K for TIP4P-FB, and Tm = 247 K for TIP4P-D. We revisited the melting point of TIP4P/2005 and TIP5P obtaining Tm = 250 and 274 K, respectively. We summarize the current situation of the melting point of ice Ih for a number of water models and conclude that no model is yet able to simultaneously reproduce the melting temperature of ice Ih and the temperature of the maximum in density at room pressure. This probably points toward our both still incomplete knowledge of the potential energy surface of water and the necessity of incorporating nuclear quantum effects to describe both properties simultaneously.
Insect detection from imagery using YOLOv3-based adaptive feature fusion convolution network
Authors: Amrani Abderraouf , Sohel Ferdous , Diepeveen Dean , Murray David , Jones Michael G. K. 
Published: June 2022

Context Insects are a major threat to crop production. They can infect, damage, and reduce agricultural yields. Accurate and fast detection of insects will help insect control. From a computer algorithm point of view, insect detection from imagery is a tiny object detection problem. Handling detection of tiny objects in large datasets is challenging due to small resolution of the insects in an image, and other nuisances such as occlusion, noise, and lack of features. Aims Our aim was to achieve a high-performance agricultural insect detector using an enhanced artificial intelligence machine learning technique. Methods We used a YOLOv3 network-based framework, which is a high performing and computationally fast object detector. We further improved the original feature pyramidal network of YOLOv3 by integrating an adaptive feature fusion module. For training the network, we first applied data augmentation techniques to regularise the dataset. Then, we trained the network using the adaptive features and optimised the hyper-parameters. Finally, we tested the proposed network on a subset dataset of the multi-class insect pest dataset Pest24, which contains 25 878 images. Key results We achieved an accuracy of 72.10%, which is superior to existing techniques, while achieving a fast detection rate of 63.8 images per second. Conclusions We compared the results with several object detection models regarding detection accuracy and processing speed. The proposed method achieved superior performance both in terms of accuracy and computational speed. Implications The proposed method demonstrates that machine learning networks can provide a foundation for developing real-time systems that can help better pest control to reduce crop damage.
Myeloid caspase-8 restricts RIPK3-dependent proinflammatory IL-1β production and CD4 T cell activation in autoimmune demyelination
Authors: Kim Sunja , Lu Hsueh Chung , Steelman Andrew J. , Li Jianrong 
Published: June 2022

Caspase-8 functions at the crossroad of programmed cell death and inflammation. Here, using genetic approaches and the experimental autoimmune encephalomyelitis model of inflammatory demyelination, we identified a negative regulatory pathway for caspase-8 in infiltrated macrophages whereby it functions to restrain interleukin (IL)-1β–driven autoimmune inflammation. Caspase-8 is partially activated in macrophages/microglia in active lesions of multiple sclerosis. Selective ablation of
Casp8
in myeloid cells, but not microglia, exacerbated autoimmune demyelination. Heightened IL-1β production by caspase-8–deficient macrophages underlies exacerbated activation of encephalitogenic T cells and production of GM-CSF and interferon-γ. Mechanistically, IL-1β overproduction by primed caspase-8–deficient macrophages was mediated by RIPK1/RIPK3 through the engagement of NLRP3 inflammasome and was independent of cell death. When instructed by autoreactive CD4 T cells in the presence of antigen, caspase-8–deficient macrophages, but not their wild-type counterparts, released significant amount of IL-1β that in turn acted through IL-1R to amplify T cell activation. Moreover, the worsened experimental autoimmune encephalomyelitis progression in myeloid
Casp8
mutant mice was completely reversed when
Ripk3
was simultaneously deleted. Together, these data reveal a functional link between T cell-driven autoimmunity and inflammatory IL-1β that is negatively regulated by caspase-8, and suggest that dysregulation of the pathway may contribute to inflammatory autoimmune diseases, such as multiple sclerosis.
陈述句的语篇角色
Authors: Zhenhua Wang , Chunhui Zhang 
Published: June 2022

提要在社会互动中，不管是口语还是书面语，语篇总是有起始、发展和终结。语篇分析或语类研究对语篇的起始、发展与终结的研究成果丰硕。语法学研究陈述句时主要关注语法结构及其意义，很少将陈述句置于语篇中讨论它们扮演的起始、发展和终结的语篇角色。本文在陈述句语法功能的基础上，在系统功能语言学框架下，将陈述句置于大语篇中进行研究，从语篇语义视角讨论陈述句的语篇角色，探索它们的生成机制以及对语篇组织策略的贡献，以此为不同句类的语篇角色研究带来启示。
Similitudes y diferencias en la expresión del sujeto pronominal en una misma comunidad de habla
Authors: Manjón-Cabeza Cruz Antonio , Granados Romero Isabel 
Published: June 2022

AbstractoGranada y Málaga pertenecen a la misma comunidad: Andalucía. Basándonos en PRESEEA, analizamos la expresión variable de los sujetos pronominales en ambas ciudades. Observamos que hay similitudes en la expresión de los factores lingüísticos, aunque la tasa pronominal es diferente: 17,7% para Granada y 27,4% para Málaga. Estas diferencias porcentuales no se explican por la ambigüedad fonética que se deriva de la pérdida de /-s/. La expresión deltúinespecífico proporciona solo una explicación parcial, que ha de completarse con la existencia de diferentes estilos comunicativos en la expresión de los pronombres sujetos que representan a los participantes en la entrevista (tú, yo, nosotros). A ello se suma la situación de cambio lingüístico por convergencia con la variedad centro-norte de la variedad peninsular, aún en proceso en Málaga.
Spatial prepositions min and ʕan in Traditional Negev Arabic
Authors: Henkin Roni , Cerqueglini Letizia 
Published: June 2022

Abstract
The Arabic prepositions min and ʕan in their prototypical spatial use relate to
the Source domain, translating as ‘(away) from’. In many contemporary dialects ʕan is absent or limited to
secondary, non-spatial meanings. In Traditional Negev Arabic, however, both prepositions are used complementarily. The proto-scene
of ablative min is a Figure (F) exiting from a 3-dimensional Ground (G)-source, with ‘containment’ and
‘boundary-crossing’ typical components of the scene. The preposition ʕan prototypically fulfils a separative
function, denoting separation from a Source with no relevance to dimensions, and has developed secondary modal functions. Both
also have perlative functions and may appear in static scenes. Only min heads prepositional complexes, where it
typically restores the nominal origin of the following element as a bounded region. So ‘min behind the house’ may
denote ‘in the back zone of the house’; these complexes characterize multiple axes, when F crosses G’s path.