bluuebunny/crossref_metadata_2025_split huggingface dataset:
Normativity in social accounts of reasoning: a Rylean approach
Authors: Kalis Annemarie 
Published: August 2022

AbstractIn recent years, the philosophy and psychology of reasoning have made a ‘social turn’: in both disciplines it is now common to reject the traditional picture of reasoning as a solitary intellectual exercise in favour of the idea that reasoning is a social activity driven by social aims. According to the most prominent social account, Mercier and Sperber’s interactionist theory, this implies that reasoning is not a normative activity. As they argue, in producing reasons we are not trying to ‘get things right’; instead our aims are to justify ourselves and persuade others to accept our views. I will argue that even if interactionism has played a crucial role in bringing about the ‘social turn’ in our thinking about reasoning, it does not convince in its claim that reasoning is not a normative activity. Moreover, I argue that it is in fact perfectly possible to understand reasoning as a social tool that is also aimed at getting things right. I will propose that Gilbert Ryle’s conceptualization of reasoning as ‘didactic discourse’ offers one possible way to understand reasoning as both social and normative activity, and that as such his ideas could be of great value for the social turn in our thinking about reasoning.
Large area, stretchable, wearable, screen-printed carbon heaters for use in elite sport
Authors: Claypole Andrew , Claypole James , Leeder Jonathan , Stevens Greg , Johnson Fiona , Bezodis Neil , Parker Matt , Claypole Tim , Gethin David , Kilduff Liam 
Published: August 2022

AbstractStretchable, nanocarbon heaters were screen-printed onto a stretchable film to create a passive heat maintenance device for elite sport. The heat uniformity and the temperature performance of these lightweight, large area electrothermal heaters were evaluated over a range of applied voltages using thermal imaging. The heaters provided a uniform heat over the 15 × 4 cm area with temperatures of 39°C, 54°C, and 72°C at 10, 15, and 20 V, respectively, within 150 s of being switched on. Tensile testing was used to examine the performance of the heaters under strain. At 20% nominal strain, the heaters gave a uniform heat output and a temperature of 44°C at 15 V, making it a promising candidate for wearable applications. The heaters were capable of maintaining temperatures of 40°C over 10 cyclic strains up to 10% nominal strain. The heaters were integrated into a proof-of-concept stretchable base-layer garment, with the effect of the heaters on skin temperature measured and thermal sensation evaluated during a simulated training session in an environmental chamber at an ambient temperature 0°C. The printed heaters maintained skin temperature and thermal sensation when compared with an unheated control.
miRNA-23b-5p affects the proliferation, migration and invasion of osteosarcoma by targeting TMEM127
Authors: Zu Dan , Dong Qi , Yao Jun , Chen Sunfang , Fang Bin , Ma Jun , Wu Bing 
Published: August 2022

Abstract
Background
Osteosarcoma (OS) has become one of the highest mortality cancers in the world due to its late diagnosis, rapid metastasis and rapid recurrence. MicroRNAs can regulate a variety of signaling pathwas involved in cancer development, such as cell proliferation, apoptosis and migration.

Objective
In this study, we studied the biological effects and molecular regulation of mir-23b-5p on human osteosarcoma cells.

Methods
The proliferation of mir-23b-5p in osteosarcoma was measured by CCK8 method and EDU method. In addition, the target population was screened through the database, and the luciferase reporter gene was used to determine the association between miRNA and target gene TMEM127. We verified this result by Western blot.

Results
We found that mir-23b-5p promotes the progression of osteosarcoma by regulating TMEM127.

Conclusions
The results of this study show that mir-23b-5p affects the proliferation, metastasis and invasion of OS by targeting TMEM127.
An enabling Framework for Blockchain in Tourism
Authors: Balasubramanian Sreejith , Sethi Jaspreet Singh , Ajayan Shalini , Paris Cody Morris 
Published: August 2022

AbstractThis viewpoint article proposes an enabling framework that identifies the use of various blockchain technologies in tourism and their applications (digitalization, automation, disintermediation, and intelligent environment) across the different stages of travel (pre-trip, during the trip, and post-trip). As we know, the tourism sector contributes immensely to world GDP and job creation. However, the COVID-19 pandemic, even after two years since it first appeared, continues to adversely impact the tourism prospects of countries across the world due to nationwide lockdowns and travel restrictions. As the world tries to adapt to the “new normal,“ the tourism sector is forced to re-think its ways of doing business and bring about innovations to facilitate the new norms of contactless and safe transactions. Also, the sector, more than ever, need to effectively deal with its inherent challenges such as transparency and credibility of information, fraudulent practices, opportunistic behavior of intermediaries, and foreign currency risks. Blockchain technology can transform the tourism sector by offering innovative solutions that address its pressing issues. However, our current understanding of blockchain application in tourism is quite limited, with previous work being largely fragmented and narrow in terms of both scope and application. We foresee that the insights offered in this viewpoint, including the framework, will advance both theory and practice and facilitate the implementation of blockchain-enabled solutions across different travel stages.
Kinetic field theory for cosmic structure formation
Authors: Konrad Sara , Bartelmann Matthias 
Published: August 2022

AbstractWe apply kinetic field theory to non-linear cosmic structure formation. Kinetic field theory decomposes the cosmic density field into particles and follows their trajectories through phase space. We assume that initial particle momenta are drawn from a Gaussian random field. We place particular emphasis on the late-time, asymptotic behaviour on small spatial scales of low-order statistical measures for the distribution of particles in configuration and velocity space. Our main result is that the power spectra for density and velocity fluctuations in ensembles of particles freely streaming along Zel’dovich trajectories asymptotically fall off with wave numberklike$$k^{-3}$$k-3for$$k\rightarrow \infty $$k→∞, irrespective of the cosmological model and the type of dark matter assumed, with the exponent set only by the number of spatial dimensions. This conclusion remains valid for density-fluctuation power spectra if particle interactions are taken into account in a mean-field approximation. We also show that the bispectrum of freely streaming particles falls off asymptotically like$$k^{-11/2}$$k-11/2under the same general conditions.
Dynamic Landscapes of tRNA Transcriptomes and Translatomes in Diverse Mouse Tissues
Authors: Yu Peng , Zhou Siting , Gao Yan , Liang Yu , Guo Wenbing , Wang Dan Ohtan , Ding Shuaiwen , Lin Shuibin , Wang Jinkai , Cun Yixian 
Published: August 2022

Abstract
Although the function of tRNAs in the translational process is well established, it remains controversial whether tRNA abundance is tightly associated with translational efficiency (TE) in mammals. Moreover, how critically the expression of tRNAs contributes to the establishment of tissue-specific proteomes in mammals has not been well addressed. Here, we measured both tRNA expression using demethylase-tRNA sequencing (DM-tRNA-seq) and TE of mRNAs using ribosome-tagging sequencing (RiboTag-seq) in the brain, heart, and testis of mice. Remarkable variation in the expression of tRNA isodecoders was observed among different tissues. When the statistical effect of isodecoder-grouping on reducing variations is considered through permutating the anticodons, we observed an expected reduction in the variation of anticodon expression across all samples, an unexpected smaller variation of anticodon usage bias, and an unexpected larger variation of tRNA isotype expression at amino acid level. Regardless of whether or not they share the same anticodons, the isodecoders encoding the same amino acids are co-expressed across different tissues. Based on the expression of tRNAs and the TE of mRNAs, we find that the tRNA adaptation index (tAI) and TE are significantly correlated in the same tissues but not between tissues; and tRNA expression and the amino acid composition of translating peptides are positively correlated in the same tissues but not between tissues. We therefore hypothesize that the tissue-specific expression of tRNAs might be due to post-transcriptional mechanisms. This study provides a resource for tRNA and translation studies, as well as novel insights into the dynamics of tRNAs and their roles in translational regulation.
Building better global data governance
Authors: Kuzio Jacqueline , Ahmadi Mohammad , Kim Kyoung-Cheol , Migaud Michael R. , Wang Yi-Fan , Bullock Justin 
Published: August 2022

Abstract
In this article, we explore the challenges of global governance and the particular challenge presented by global data governance. We discuss a range of challenges to developing meaningful global governance institutions for regulating how companies and governments around the world manage and utilize consumer data. These challenges are compounded by their global nature and the complexities of Internet-based technologies. We argue that the following gaps exist for effective global data governance: (a) there is no overarching global framework for protecting consumer data, and it is partial and incomplete; (b) there is a lack of data protection for international data transfers, as much of the regulation that is being developed is not global in scale; and (c) new areas of data collection and use compound concerns to effective data governance in a globalized digital world. Moreover, we highlight important needs in terms of both global governance and impending challenges related to current and new uses of data. Any global governance framework should recognize the need for an iterative process where communication is ongoing between the necessary stakeholders. Agreements should incorporate common goals to maximize the potential development of global data governance norms. However, goals must remain flexible to the different data environments across nation-states while maintaining a global scope to ensure data protection. In addition, any agreement should consider the emerging challenges in this area. These challenges include new methods of data collection and use, as well as protecting individuals from manipulation and undue influence based on how their data are being used, processed, and collected.
Psychological distress among healthcare workers post COVID-19 pandemic: from the resilience of individuals to healthcare systems
Authors: O’Donnell S. , Quigley E. , Hayden J. , Adamis D. , Gavin B. , McNicholas F. 
Published: August 2022

AbstractSince the emergence of the COVID-19 pandemic, there has been increased interest in identifying ways of protecting the mental well-being of healthcare workers (HCWs). Much of this has been directed towards promoting and enhancing the resilience of those deemed as frontline workers. Based on a review of the extant literature, this paper seeks to problematise aspects of how ‘frontline work’ and ‘resilience’ are currently conceptualised. Firstly, frontline work is arbitrarily defined and often narrowly focused on acute, hospital-based settings, leading to the needs of HCWs in other sectors of the healthcare system being overlooked. Secondly, dominant narratives are often underpinned by a reductionist understanding of the concept of resilience, whereby solutions are built around addressing the perceived deficiencies of (frontline) HCWs rather than the structural antecedents of distress. The paper concludes by considering what interventions are appropriate to minimise the risk of burnout across all sectors of the healthcare system in a post-pandemic environment.
Daily variations in Western Greenland slush limits, 2000–2021
Authors: Machguth Horst , Tedstone Andrew J. , Mattea Enrico 
Published: August 2022

AbstractThe marginal areas of the Greenland ice sheet develop streams and lakes each summer, documenting that surface runoff of meltwater is a major component of ice-sheet mass balance. Here we map the slush limit, a proxy for the extent of surface runoff, using daily MODIS data for the years 2000–2021. We develop an automated algorithm capable of detecting daily slush limits, provided sufficient image quality. The algorithm is applied to the ice sheet's western flank (61.7 $^{\circ }$N to 76.5 $^{\circ }$N). We find significant increasing trends in maximum slush limits until the year 2012, but not thereafter. We show that the slush limit typically rises quickly early in the ablation season but stabilizes before melting ceases. The data provide evidence that upward migration of surface runoff in summer 2012 stopped early at the upper margin of the ice slabs. These thick and continuous ice layers are located close to the surface, in the firn, and impede percolation of melt into deeper pore space. Had the ice slabs extended higher, the summer 2012 provided sufficient energy to raise the slush limit by another $\sim$300 m in elevation.
Small but mighty: how overlooked small species maintain community structure through middle Eocene climate change
Authors: Kearns L. E. , Bohaty S. M. , Edgar K. M. , Ezard T. H. G. 
Published: August 2022

AbstractUnderstanding current and future biodiversity responses to changing climate is pivotal as anthropogenic climate change continues. This understanding is complicated by the multitude of available metrics to quantify dynamics and by biased sampling protocols. Here, we investigate the impact of sampling protocol strategies using a data-rich fossil record to calculate effective diversity using Hill numbers for the first time on Paleogene planktonic foraminifera. We sample 22,830 individual tests, in two different size classes, across a 7 Myr time slice of the middle Eocene featuring a major transient warming event, the middle Eocene climatic optimum (MECO; ~40 Ma), at study sites in the midlatitude North Atlantic. Using generalized additive models, we investigate community responses to climatic fluctuations. After correcting for any effects of fossil fragmentation, we show a peak in generic diversity in the early and middle stages of the MECO as well as divergent trajectories between the typical size-selected community (>180 μm) and a broader assemblage, including smaller genera (>63 μm). Assemblages featuring smaller genera are more resilient to the climatic fluctuations of the MECO than those assemblages that feature only larger genera, maintaining their community structure at the reference Hill numbers for Shannon's and Simpson's indices. These results raise fundamental questions about how communities respond to climate excursions. In addition, our results emphasize the need to design studies with the aim of collecting the most inclusive data possible to allow detection of community changes and determine which species are likely to dominate future environments.
STRICHARTZ ESTIMATES FOR THE WAVE EQUATION INSIDE CYLINDRICAL CONVEX DOMAINS
Authors: MEAS LEN 
Published: August 2022

AbstractWe establish local-in-time Strichartz estimates for solutions of the model case Dirichlet wave equation inside cylindrical convex domains
$\Omega \subset \mathbb {R}^ 3$
with smooth boundary
$\partial \Omega \neq \emptyset $
. The key ingredients to prove Strichartz estimates are dispersive estimates, energy estimates, interpolation and
$TT^*$
arguments. Strichartz estimates for waves inside an arbitrary domain
$\Omega $
have been proved by Blair, Smith and Sogge [‘Strichartz estimates for the wave equation on manifolds with boundary’, Ann. Inst. H. Poincaré Anal. Non Linéaire26 (2009), 1817–1829]. We provide a detailed proof of the usual Strichartz estimates from dispersive estimates inside cylindrical convex domains for a certain range of the wave admissibility.
Risk aversion and cleaner cooking fuel choice: an empirical study in Ghana
Authors: Adjei-Mantey Kwame , Takeuchi Kenji 
Published: August 2022

AbstractCleaner cooking is an important policy objective in the bid to achieve sustainable development. Despite efforts to encourage cleaner cooking fuel use, biomass fuel is still widely used in many developing countries. This study investigates the role of behavioral factors, particularly risk aversion, in the choice of cooking fuels in Ghana. In addition, we investigate how the improvement of supply infrastructure and services mitigates the impact of risk preferences in fuel choices. By employing data from the recent round of the Ghana Living Standards Survey, we find that risk-averse households are less likely to choose liquified petroleum gas as their cooking fuel. However, the effect is mitigated for households located in districts with more supply infrastructure. Additional analyses reveal the influence of risk and time preferences in other household behavior.
The Shiraz Connection: A Shāhnāma of 1440 from the Library of Muḥammad Shāh, Sultan of Gujarat
Authors: SHOVELTON EMILY 
Published: August 2022

AbstractThis article offers a new perspective on the relationship between manuscript production in Shiraz under the Timurids and in the Sultanate states of South Asia. During the so-called long fifteenth century, between Timur's invasion in 1398 and Humāyūn's return to India in 1555, there was a surge of creativity in the arts, despite the fractured political landscape of multiple courts. The resulting material culture is vibrant and diverse and belies prevalent historiography, which often portrays this period as culturally barren. The discussion will focus on an illustrated copy of the Shāhnāma of Firdausi dated 843/1440, currently in the Khuda Bakhsh Library in Patna, once owned by Muḥammad Shāh, Sultan of Gujarat. A study of this manuscript and its cultural context challenges the notion that ‘outmoded’ traits are the key criteria of a Persian manuscript's possible Sultanate origin. This article further aims to initiate a re-examination of the reception and dispersal of Persian manuscripts in the Indian Sultanates and the future lives of a particular group of manuscripts made in Shiraz.
Jovian Auroral Electron Precipitation Budget—A Statistical Analysis of Diffuse, Mono‐Energetic, and Broadband Auroral Electron Distributions
Authors: Salveter A. , Saur J. , Clark G. , Mauk B. H. 
Published: August 2022

AbstractRecent observations by the Juno spacecraft have shown that electrons contributing to Jupiter's main auroral emission appear to be frequently characterized by broadband electron distributions, but also less often mono‐energetic electron distributions are observed as well. In this work, we quantitatively derive the occurrence rates of the various electron distributions contributing to Jupiter's aurora. We perform a statistical analysis of electrons measured by the JEDI‐instrument within 30–1,200 keV from Juno's first 20 orbits. We determine the electron distributions, either pancake, field‐aligned, mono‐energetic, or broadband, through energy and pitch angles to associate various acceleration mechanisms. The statistical analysis shows that field‐aligned accelerated electrons at magnetic latitudes greater than 76° are observed in 87.6% ± 7.2% of the intervals time averaged over the dipole L‐shells according the main oval. Pancake distributions, indicating diffuse aurora, are prominent at smaller magnetic latitudes (<76°) with an occurrence rate of 86.2% ± 9.6%. Within the field‐aligned electron distributions, we see broadband distributions 93.0% ± 3.8% of the time and a small fraction of isolated mono‐energetic distribution structures 7.0% ± 3.8% of the time. Furthermore, these occurrence statistics coincide with the findings from our energy flux statistics regarding the electron distributions. Occurrence rates thus also characterize the overall energetics of the different distribution types. This study indicates that stochastic acceleration is dominating the auroral processes in contrast to Earth where the discrete aurora is dominating.
Bayesian Multi‐Model Estimation of Fault Slip Distribution for Slow Slip Events in Southwest Japan: Effects of Prior Constraints and Uncertain Underground Structure
Authors: Agata R. , Nakata R. , Kasahara A. , Yagi Y. , Seshimo Y. , Yoshioka S. , Iinuma T. 
Published: August 2022

AbstractWe consider a Bayesian multi‐model fault slip estimation (BMMFSE), which incorporates many candidates of the underground structure (Earth structure and plate boundary geometry) model characterized by a prior probability density function (PDF). The technique is used to study long‐term slow slip events (L‐SSEs) that occurred beneath the Bungo Channel, southwest Japan, in around 2010 and 2018. We here focus on the two advantages of BMMFSE: First, it allows for estimating slip distribution without introducing relatively strong prior information such as smoothing constraints, by combining a fully Bayesian inference and better consideration of model uncertainty to avoid overfitting. Second, the posterior PDF for the underground structure is also obtained during the fault slip estimation, which can be used as priors for the estimation of slip distribution for recurring events. The estimated slip distribution obtained using BMMFSE agreed better with the distribution of deep tectonic tremors at the down‐dip side of the main rupture area than those based on stronger prior constraints when the corresponding Coulomb failure stress changes are compared. This finding suggests a mechanical relationship between the L‐SSE and the synchronized tremors. The use of the posterior PDF of the underground structure estimated for the 2010 L‐SSE as prior PDF for the 2018 event resulted in more consistent estimation with the data, indicated by a smaller value of an information criterion.
Multi‐Decadal Simulation of Marsh Topography Under Sea Level Rise and Episodic Sediment Loads
Authors: Brand M. W. , Buffington K. , Rogers J. B. , Thorne K. , Stein E. D. , Sanders B. F. 
Published: August 2022

AbstractCoastal marsh within Mediterranean climate zones is exposed to episodic watershed runoff and sediment loads that occur during storm events. Simulating future marsh accretion under sea level rise calls for attention to: (a) physical processes acting over the time scale of storm events and (b) biophysical processes acting over time scales longer than storm events. Using the upper Newport Bay in Southern California as a case study, we examine the influence of event‐scale processes on simulated change in marsh topography by comparing: (a) a biophysical model that integrates with an annual time step and neglects event‐scale processes (BP‐Annual), (b) a physical model that resolves event‐scale processes but neglects biophysical interactions (P‐Event), and (c) a biophysical model that resolves event‐scale physical processes and biophysical processes at annual and longer time scales (BP‐Event). A calibrated BP‐Event model shows that large (>20‐year return period) episodic storm events are major drivers of marsh accretion, depositing up to 30 cm of sediment in one event. Greater deposition is predicted near fluvial sources and tidal channels and less on marshes further from fluvial sources and tidal channels. In contrast, the BP‐Annual model poorly resolves spatial structure in marsh accretion as a consequence of neglecting event‐scale processes. Furthermore, the P‐Event model significantly overestimates marsh accretion as a consequence of neglecting marsh surface compaction driven by annual scale biophysical processes. Differences between BP‐Event and BP‐Annual models translate up to 20 cm per century in marsh surface elevation.