bluuebunny/crossref_metadata_2025_split huggingface dataset:
Post-traumatic growth in polytraumatized patients after 20+ years: a long-term follow-up study of 337 patients treated at a level 1 trauma center
Authors: Kalbas Yannik , Halvachizadeh Sascha , Kumabe Yohei , Luidl Anna Theresa , Steel Jennifer Lynne , Zelle Boris A. , Cinelli Paolo , Pape Hans-Christoph , Pfeifer Roman 
Published: June 2022

Abstract
Purpose
There is limited research on the long-term psychiatric outcomes of polytraumatized patients. Existing studies focus mainly on the negative sequelae. Post-traumatic growth (PTG) describes positive personal development after severe physical or mental distress. In this study, we investigated post-traumatic growth in polytraumatized patients at least 20 years after trauma.

Methods
Patients treated for polytrauma at a German level 1 trauma center between 1971 and 1990, were contacted 20+ years later. A questionnaire with 37 questions from the stress-related growth scale (SRGS) and the post-traumatic growth inventory (PGI) was administered. PTG was quantified in five specific areas. PTG and patient demographics were then analyzed using logistic regression.

Results
Eligible questionnaires were returned by 337 patients. 96.5% of patients reported improvements regarding at least one of the 37 questions. Approximately, a third of patients noticed distinct improvements regarding their relationship to others (29.2%), appreciation of life (36.2%) and attitudes towards new possibilities (32.5%). Patient demographics were significant predictors for the development of PTG: Older (p < 0.001), female (p = 0.042) and married patients (p = 0.047) showed a greater expression of PTG. We also saw significantly more PTG in patients with higher injury severity (p = 0.033).

Conclusion
20 years after polytrauma, patients report improvements in their relationship with others, appreciation of life and attitude towards new possibilities. Women and married patients show higher expression of PTG. Furthermore, there is higher expression of PTG with higher age and injury severity. Post-traumatic growth should be identified and fostered in clinical practice.

Level of evidence
III—prospective long-term follow-up study.
Preoperative pelvic MRI and 2-[18F]FDG PET/CT for lymph node staging and prognostication in endometrial cancer—time to revisit current imaging guidelines?
Authors: Fasmer Kristine E. , Gulati Ankush , Dybvik Julie A. , Wagner-Larsen Kari S. , Lura Njål , Salvesen Øyvind , Forsse David , Trovik Jone , Pijnenborg Johanna M. A. , Krakstad Camilla , Haldorsen Ingfrid S. 
Published: June 2022

Abstract
Objective
This study presents the diagnostic performance of four different preoperative imaging workups (IWs) for prediction of lymph node metastases (LNMs) in endometrial cancer (EC): pelvic MRI alone (IW1), MRI and [18F]FDG-PET/CT in all patients (IW2), MRI with selective [18F]FDG-PET/CT if high-risk preoperative histology (IW3), and MRI with selective [18F]FDG-PET/CT if MRI indicates FIGO stage ≥ 1B (IW4).

Methods
In 361 EC patients, preoperative staging parameters from both pelvic MRI and [18F]FDG-PET/CT were recorded. Area under receiver operating characteristic curves (ROC AUC) compared the diagnostic performance for the different imaging parameters and workups for predicting surgicopathological FIGO stage. Survival data were assessed using Kaplan-Meier estimator with log-rank test.

Results
MRI and [18F]FDG-PET/CT staging parameters yielded similar AUCs for predicting corresponding FIGO staging parameters in low-risk versus high-risk histology groups (p ≥ 0.16). The sensitivities, specificities, and AUCs for LNM prediction were as follows: IW1—33% [9/27], 95% [185/193], and 0.64; IW2—56% [15/27], 90% [174/193], and 0.73 (p = 0.04 vs. IW1); IW3—44% [12/27], 94% [181/193], and 0.69 (p = 0.13 vs. IW1); and IW4—52% [14/27], 91% [176/193], and 0.72 (p = 0.06 vs. IW1). IW3 and IW4 selected 34% [121/361] and 54% [194/361] to [18F]FDG-PET/CT, respectively. Employing IW4 identified three distinct patient risk groups that exhibited increasing FIGO stage (p < 0.001) and stepwise reductions in survival (p ≤ 0.002).

Conclusion
Selective [18F]FDG-PET/CT in patients with high-risk MRI findings yields better detection of LNM than MRI alone, and similar diagnostic performance to that of MRI and [18F]FDG-PET/CT in all.

Key Points
• Imaging by MRI and [18F]FDG PET/CT yields similar diagnostic performance in low- and high-risk histology groups for predicting central FIGO staging parameters.
• Utilizing a stepwise imaging workup with MRI in all patients and [18F]FDG-PET/CT in selected patients based on MRI findings identifies preoperative risk groups exhibiting significantly different survival.
• The proposed imaging workup selecting ~54% of the patients to [18F]FDG-PET/CT yield better detection of LNMs than MRI alone, and similar LNM detection to that of MRI and [18F]FDG-PET/CT in all.
Long-term safety of withholding standard prophylaxis in patients with moderate chronic kidney disease
Authors: Nijssen E. C. , Nelemans P. J. , Rennenberg R. J. , van Ommen G. V. , Wildberger J. E. 
Published: June 2022

Abstract
In the latest ESUR contrast media guidelines, standard prophylaxis is no longer recommended for patients with moderate chronic kidney disease (CKD). In the absence of solid evidence, guideline updates are often based on indirect evidence and expert opinion. Likewise, evidence supporting the withdrawal of standard prophylaxis in moderate CKD patients was scarce and mostly indirect, but did include one randomised controlled trial evaluating guideline-recommended standard prophylactic intravenous hydration against a group receiving no prophylaxis (A MAastricht Contrast-Induced Nephropathy Guideline (AMACING) trial). Since then, benefits of the updated guideline recommendation for patient and hospital burden have been numerated and were shown to be substantial. The current special report provides data on long-term safety from the AMACING randomised controlled trial.

Key Points
• In the latest version of ESUR clinical practice guidelines for safe use of contrast media, standard prophylaxis is no longer recommended for patients with moderate chronic kidney disease.
• Benefits of this change in recommendations for patient and hospital burden have been numerated. The current report provides data on long-term safety from the AMACING randomised controlled trial.
• No disadvantage of withholding prophylaxis could be discerned. Results suggest that, in this population, underlying disease is more relevant for survival and prognosis than contrast administration itself.
Improvement of Part Accuracy by Combination of Pulsed Wave (PW) and Continuous Wave (CW) Laser Powder Bed Fusion
Authors: Laag Thomas , Winkel Till Martin , Jauer Lucas , Heußen Daniel , Haefner Constantin Leon 
Published: June 2022

AbstractIn this paper, a processing strategy is investigated to increase the geometric accuracy of parts fabricated by laser powder bed fusion (LPBF). Pulsed wave emission (pw) is used for contour exposure in combination with a continuous wave (cw) emission for bulk volume exposure. With the goal of discrete solidification of adjacent melt pools, process parameters of laser power PL, scanning speed vs, and relative pulse overlap ∆xo are developed for contour exposure. Samples with variable contour angles are fabricated to investigate the effect of the pw contour exposure on excessive melting in critical areas of the part prone to overheating. Geometric accuracy and surface roughness are evaluated using SEM images of surface topography and optical surface roughness measurements, respectively. It is observed that excessive melting can be suppressed by using pw contour exposure and usage of modified process parameters. Due to the discretized energy input in pw emission mode, smaller melt pools with lower melt pool fluctuation and powder erosion are produced. The maximum applicable scanning speed is limited by the solidification time of the melt pool and is significantly lower compared to conventional cw contour exposure parameters. Therefore, a combination of cw volume exposure with high process productivity and pw contour exposure for high geometric accuracy is beneficial to limit productivity losses and increase accuracy in part building.
Revisiting the adequacy of the economic policy narrative underpinning the Green Revolution
Authors: van Etten Jacob 
Published: June 2022

AbstractThe Green Revolution still exerts an important influence on agricultural policy as a technology-centred development strategy. A main policy narrative underpinning the Green Revolution was first expounded inTransforming Traditional Agriculture(TTA), a book published in 1964 by Nobel Prize-winning economist Ted Schultz. He famously argued that traditional farmers were ‘poor but efficient’. As farmers responded to economic incentives, technology-driven strategies would transform traditional agriculture into an engine of economic growth. Schultz relied on published ethnographic data and his own calculations to construct this policy narrative. My reanalysis ofTTAfocuses on its main case study, Panajachel, a village in Guatemala. I follow a narrative approach, evaluating whether Schultz’s story relates a plausible account of agricultural development in Panajachel and its region. I show how Schultz deliberately tried to hide that Mayan farmers in Panajachel were not challenged in technological terms and were able to reach relatively high economic returns. His interpretation of the Guatemalan rural economy ignored ethnic tensions dominating market exchange, a main barrier for agricultural development. I evaluate Schultz’s narrative further by tracing the subsequent evolution of Panajachel and its wider region. High-input strategies had to address ethnic barriers and change agents became embroiled in violent conflict along ethnic lines. Assessing the adequacy of Schultz’s contribution,from a narrative approach, shows how he ‘got the story wrong’ and that the Green Revolution policy narrative has an excessively narrow intellectual basis. New narratives should reserve a much more important place for institutional change in agricultural development.
Evaluation of Bookkeeper mass deacidification based on historical book papers
Authors: Malešič Jasna , Marinšek Marjan , Kralj Cigić Irena 
Published: June 2022

AbstractBookkeeper, the most widely used deacidification process based on MgO particles, was systematically evaluated on two sets of nonvaluable historical paper samples. Established analytical methods, such as pH and alkaline reserve determination, were used, as well as SEM EDS analyses to evaluate the distribution of Mg-rich particles on the paper surface and in the cross-section of the paper. The degradation rate constants of untreated and deacidified paper samples after accelerated thermal degradation were calculated based on weight average molecular mass determination to evaluate the lifetime extension of paper. The efficiency factors determined after accelerated thermal degradation of untreated and treated paper showed that paper lifetime prolongation after Bookkeeper deacidification treatment is highly limited for most of the investigated paper samples. No correlation was found between the alkaline reserve content or the pH and the degradation rate constants of the deacidified paper samples, but the paper degradation rate correlated with the paper samples pH before deacidification treatment. SEM EDS analysis showed that Mg-rich particles remained on the paper surface, which explains the limited effectiveness of the treatment.
Graphical abstract
Using the Griffiths Mental Development Scales to Evaluate a Developmental Profile of Children with Autism Spectrum Disorder and Their Symptomatologic Severity
Authors: Pino Maria Chiara , Donne Ilenia Le , Vagnetti Roberto , Tiberti Sergio , Valenti Marco , Mazza Monica 
Published: June 2022

AbstractEarly diagnosis is crucial for Autism spectrum disorder (ASD) and is achieved through a screening of developmental indicators to recognise children who are at risk of autism. One of the most widely used instruments in clinical practice for assessing child development is the Griffiths Mental Development Scale (GMDS). We sought (a) to assess longitudinally whether children diagnosed with ASD, with a mean age of 33.50 months (SD 7.69 months), show a developmental delay of abilities measured by the GMDS over time and (b) to analyse which skills of the GMDS could be associate to the symptomatologic severity of ASD. Our results showed lower scores of General Quotient and all sub-quotients of GMDS from first (T0) to second assessment (T1), except for the Performance sub-quotient. Three sub-quotients (Personal-Social, Hearing and Language and Practical Reasoning) also associate symptom severity at the time when the diagnosis of ASD is made.
Russian climate scepticism: an understudied case
Authors: Ashe Teresa , Poberezhskaya Marianna 
Published: June 2022

Abstract
In this paper, we consider climate scepticism in the Russian context. We are interested in whether this has been discussed within the social scientific literature and ask first whether there is a discernible climate sceptical discourse in Russia. We find that there is very little literature directly on this topic in either English or Russian and we seek to synthesise related literature to fill the gap. Secondly, we consider whether Russian climate scepticism has been shaped by the same factors as in the USA, exploring how scientists, the media, public opinion, the government and business shaped climate scepticism in Russia. Climate scepticism in the USA is understood as a ‘conservative countermovement’ that seeks to react against the perceived gains of the progressive environmental movement, but we argue that this is not an appropriate framework for understanding Russian climate scepticism. Articulated within a less agonistic environment and situated within an authoritarian regime, Russian expressions of climate scepticism balance the environmental, political and economic needs of the regime under the constraints of a strong ‘carbon culture’ and closed public debate.
Extraction of density-layered fluid from a porous medium
Authors: Jose J. , Hocking G. C. , Farrow D. E. 
Published: June 2022

AbstractWe consider axisymmetric flow towards a point sink from a stratified fluid in a vertically confined aquifer. We present two approaches to solve the equations of flow for the linear density gradient case. Firstly, a series method results in an eigenfunction expansion in Whittaker functions. The second method is a finite difference method. Comparison of the two methods verifies the finite difference method is accurate, so that more complicated nonlinear, density stratification can be considered. Interesting results for the case where the density stratification changes from linear to almost two-layer are presented, showing that in the nonlinear stratification case, there are certain values of flow rate for which a steady solution does not occur. A spectral method is then implemented to consider cases in which there is a stagnant region beneath a sharp interface between two layers of different, but constant, density. In this situation, flows also exist only for flow rates beneath a critical flux value, consistent with the results for the continuous density stratification.
Impact of pulmonary vein variant anatomy and cross-sectional orifice area on freedom from atrial fibrillation recurrence after cryothermal single-shot guided pulmonary vein isolation
Authors: Guckel Denise , Lucas Philipp , Isgandarova Khuraman , Hamriti Mustapha El , Bergau Leonard , Fink Thomas , Sciacca Vanessa , Braun Martin , Khalaph Moneeb , Imnadze Guram , Nölker Georg , Sommer Philipp , Sohns Christian 
Published: June 2022

Abstract

Background
Cryoballoon (CB)-guided pulmonary vein isolation (PVI) is an established treatment for atrial fibrillation (AF). This study aimed to evaluate ablation efficacy and freedom from arrhythmia recurrence using the novel POLARx compared to the Arctic Front Advance Pro (AFA) CB system including the analysis of individual PV characteristics.

Methods
A total of 687 patients underwent CB-guided ablation for AF. Arrhythmia recurrence was defined as an ECG documented episode of any AF/atrial tachycardia (AT) > 30 s. Anatomical characteristics were assessed using magnetic resonance imaging (MRI). For each PV, the cross-sectional orifice area (CSOA) was determined. Follow-up examinations were scheduled after 3, 6, and 12 months.

Results
Acute PVI was achieved in all patients. Twelve-month AF-free survival was similar between the groups (POLARx 43/86 (50%) vs. AFA 318/601 (53%), Log-rank (LR) p = 0.346). MRI found a comparable percentage of patients with normal PV anatomy (POLARx 71/86 (83%) vs. AFA 530/601 (85%), p = 0.162). Patients with variant PV characteristics presented with a significantly impaired 12-month AF-free survival (normal PVs 326/585 (56%) vs. variant PVs 27/102 (27%), LR p < 0.001) independent of the applied CB ablation system. PAF patients with AF recurrence presented with significantly larger CSOA of the left-sided PVs and the right superior PVs (LSPV: p < 0.001; LIPV: p < 0.001; RSPV: p < 0.001). In PERS AF, no association between CSOA and ablation outcome was observed. Multivariate analyses identified PERS AF (hazard ratio (HR) 2.504, confidence interval (CI), 1.900–3.299, p < 0.001) and variant PV anatomy (HR 2.124, CI 1.608–2.805, p < 0.001) as independent predictors for AF recurrence.

Conclusions
Both CB ablation systems are associated with comparable 12-month AF-free survival rates. Variant PV anatomy seems to be predictive for AF recurrence. An association between CSOA and the outcome after CB-guided PVI was demonstrated for PAF.
Rhythmia zero-fluoroscopy workflow with high-power, short-duration ablation: retrospective analysis of procedural data
Authors: Cuellar-Silva Jose R. , Albrecht Elizabeth M. , Sutton Brad S. 
Published: June 2022

Abstract

Background
Fluoroscopy is commonly used during atrial fibrillation (AF) ablation to guide catheter navigation and placement. Technology improvements have significantly reduced fluoroscopy time, and subsequent radiation dose, necessary to perform successful ablations. However, there is still no amount of radiation exposure known to be completely safe. The aim of this manuscript is to describe a detailed zero-fluoroscopy RHYTHMIA HDx workflow for AF ablation.

Methods
This was an observational, single-center experience to describe the technique, acute procedural success, and safety using a novel zero-fluoroscopy workflow with the RHYTHMIA HDx mapping system and intracardiac echocardiography (ICE). Seventy-two consecutive patients undergoing de novo or redo AF ablation were retrospectively analyzed. Venous access was guided with ultrasound. ICE combined with the mapping system’s magnetic tracking and sheath detection was used for precise catheter placement in the coronary sinus, at the transseptal puncture, and in the left atrium. A high-power, short-duration ablation strategy guided by local impedance was used. Pulmonary vein isolation was performed or touched up for all patients with additional lines added at the operator’s discretion.

Results
Using this zero-fluoroscopy workflow, all patients achieved acute isolation with no significant procedure-related complications. Average procedure time was 73.7 ± 16.2 min, which included persistent (58%) and paroxysmal (42%) AF cases, and no procedures required conversion to fluoroscopy.

Conclusions
In this experience, a zero-fluoroscopy workflow using the RHYTHMIA HDx mapping system combined with ICE was feasible and safe for ablation in a heterogenous AF population. This approach, in the appropriate patient population, can eliminate radiation exposure to patients and staff.
An exact projection-based algorithm for bilevel mixed-integer problems with nonlinearities
Authors: Merkert Maximilian , Orlinskaya Galina , Weninger Dieter 
Published: June 2022

AbstractWe propose an exact global solution method for bilevel mixed-integer optimization problems with lower-level integer variables and including nonlinear terms such as, e.g., products of upper-level and lower-level variables. Problems of this type are extremely challenging as a single-level reformulation suitable for off-the-shelf solvers is not available in general. In order to solve these problems to global optimality, we enhance an approximative projection-based algorithm for mixed-integer linear bilevel programming problems from the literature to become exact under one additional assumption. This assumption still allows for discrete and continuous leader and follower variables on both levels, but forbids continuous upper-level variables to appear in lower-level constraints and thus ensures that a bilevel optimum is attained. In addition, we extend our exact algorithm to make it applicable to a wider problem class. This setting allows nonlinear constraints and objective functions on both levels under certain assumptions, but still requires that the lower-level problem is convex in its continuous variables. We also discuss computational experiments on modified library instances.
Chromoblastomycosis-Leprosy Co-Infection in Central West Brazil. Presentation of Three Cases and Literature Review
Authors: Guevara Armando , Vicente Vânia Aparecida , de Souza Lima Bruna Jacomel F. , Nery Andréia Ferreira , Hagen Ferry , Hahn Rosane Christine 
Published: June 2022

AbstractChromoblastomycosis and leprosy are chronic diseases with high prevalence in tropical and subtropical regions. Brazil is one of the countries with the highest incidence and prevalence for both diseases, however, reports of co-infections are scarce. The aim of this study was to describe three cases of chromoblastomycosis-leprosy co-infection in patients from Mato Grosso state, Brazil. A review of chromoblastomycosis-leprosy co-infection was performed of English, Portuguese and Spanish publications in LILACS, SciELO, PubMed and Web of Science databases using the descriptors (chromoblastomycosis OR cromoblastomicose OR cromoblastomicosis) AND (leprosy OR hanseníase OR lepra), without time period delimitation. Nineteen cases were included, 16 cases were published in 11 articles, plus the three cases reported in the current study. Most reported coninfection cases came from Brazil. Majority of the patients were male with a mean age of 52.2 years. Farmer was the main occupational activity reported. In 12 patients, the clinical signs and symptoms of leprosy started first. No contacts with patients affected by leprosy, armadillos or history of injuries at the anatomical site of chromoblastomycosis lesions were reported. Five leprosy patients who received steroid treatment for leprosy reactions or neuropathies, were diagnosed with chromoblastomycosis during immunosuppressive therapy. Four cases (21.1%) were reported among the elderly patients. Co-infections in patients with chromoblastomycosis or leprosy are uncommon, but the possibility should always be considered, especially if the patient is undergoing immunosuppressive treatment or is elder.