bluuebunny/crossref_metadata_2025_split huggingface dataset:
Iminium-substituted 2,3-dihydroisoxazoles: synthesis from acetylenic iminium salts and nitrones, and some transformations
Authors: Gerster Holger , Keim Michael , Maas Gerhard 
Published: May 2022

Abstract
Iminium-functionalized 2,3-dihydroisoxazoles (4-isoxazolines) were prepared in high yields by [3+2] cycloaddition of N-methyl-C-phenylnitrone and acetylenic iminium salts. Conversion of the very hygroscopic cycloadducts into neutral compounds was achieved by hydrolysis or hydride reduction of the iminium functional group. By a thermal rearrangement, the cycloadducts were converted into 2,3-dihydro-1H-imidazolium salts. With C,N-diphenylnitrone as the reaction partner, the expected cycloadduct, a [(2,3-dihydroisoxazol-4-yl)-1-(phenyl)methylene]-N,N-dimethylammonium triflate, could be prepared at −75°C and was characterized by NMR. This product was found to be thermally unstable above −30°C, being converted into an inseparable product mixture. Basic hydrolysis of this mixture afforded a structurally interesting acyclic enaminone/half-aminal, which is likely derived from a 2,3-dihydro-1,3-oxazole.
Prediction of a model crystal structure for Ni2F5 by first-principles calculations
Authors: Lindič Tilen , Sinha Shreya , Mattsson Stefan , Paulus Beate 
Published: May 2022

Abstract
Electrochemical fluorination in anhydrous HF, also known as the Simons process, is a widely used industrial method for fluorination of organic compounds. Its mechanism, being not so well understood, has long been debated and is believed to involve higher valent nickel fluorides formed on the nickel-plated anode during the process. One of these is speculated to be Ni2F5, which was previously reported in the literature and assigned via infrared spectroscopy, but its crystal structure is not yet known. We have identified known crystal structures of compounds with similar stoichiometries as Ni2F5 and utilized them as a starting point for our periodic DFT investigations, applying the PBE+U method. Ni2F5 as the most stable polymorph was found to be of the same crystal structure as another mixed valent fluoride, Cr2F5. The calculated lattice parameters are a = 7.24 Å, b = 7.40 Å, c = 7.08 Å and β = 118.9° with an antiferromagnetic ordering of the nickel magnetic moments.
Daily E-cigarette Use and the Surge in JUUL Sales: 2017–2019
Authors: Pierce John P. , Zhang Jasen , Crotty Alexander Laura E. , Leas Eric C. , Kealey Sheila , White Martha M. , Strong David R. , Trinidad Dennis R. , McMenamin Sara B. , Chen Ruifeng , Benmarhnia Tarik , Messer Karen 
Published: May 2022

OBJECTIVES
To identify how the 2017 rapid surge in sales of JUUL e-cigarettes affected usage among US youth and young adults.

METHODS
Annual surveys in the Population Assessment of Tobacco and Health Study assess tobacco use by product and brand among the US population. We identified 2 cohorts aged 14 to 34 years, 1 with baseline survey in 2014 before the rapid surge of JUUL and the other in 2017 as the surge in JUUL sales was occurring. For 5 age groups, we compared 2-year incidence of first tobacco use and of new-onset daily tobacco use by product, and report levels of dependence.

RESULTS
Sociodemographic variables and rates of experimentation with any tobacco product were similar between cohorts. Among baseline nondaily tobacco users, only those aged 14 to 17 years had an increase in the 2-year incidence of new daily tobacco use (2014 cohort = 4.8%, 95% confidence interval 4.3, 5.5 vs 2017 cohort = 6.3%, 95% confidence interval 5.8–7.0) to rates approaching those in the 1990s. In 2019, three-quarters of new daily tobacco users aged 14 to 17 vaped daily and had e-cigarette dependence scores similar to daily cigarette smokers and older adult e-cigarette vapers. We estimate that about 600 000 Americans aged &lt;21 years used JUUL products daily in 2019, a rate 2.5 times those aged 25 to 34 years.

CONCLUSIONS
The surge in US JUUL sales was associated with a sharp rise in daily e-cigarette vaping and daily tobacco use among US youth, not young adults.
Report of RILEM TC 267-TRM phase 3: validation of the R3 reactivity test across a wide range of materials
Authors: Londono-Zuluaga Diana , Gholizadeh-Vayghan Asghar , Winnefeld Frank , Avet François , Ben Haha Mohsen , Bernal Susan A. , Cizer Özlem , Cyr Martin , Dolenec Sabina , Durdzinski Pawel , Haufe Johannes , Hooton Doug , Kamali-Bernard Siham , Li Xuerun , Marsh Alastair T. M. , Marroccoli Milena , Mrak Marusa , Muy Yeakleang , Patapy Cédric , Pedersen Malene , Sabio Serge , Schulze Simone , Snellings Ruben , Telesca Antonio , Vollpracht Anya , Ye Guang , Zhang Shizhe , Scrivener Karen L. 
Published: May 2022

AbstractRILEM TC 267 TRM– “Tests for Reactivity of Supplementary Cementitious Materials” recommends the Rapid Reliable Relevant (R3) test as a method for determining the chemical reactivity of supplementary cementitious materials (SCMs) in Portland cement blends. In this paper, the R3 test was applied to 52 materials from a wide range of conventional and alternative SCMs with the aim to validate such test. An excellent correlation was found between the cumulative heat release and the bound water determined following the R3 test method. Comparison of the R3 test results to mortar compressive strength development showed that all conventional SCMs (e.g. blast furnace slag and fly ashes) followed the same trend, with the notable exception of very reactive calcined kaolinitic clays. It is discussed, through an in-depth statistical regression analysis of the R3 reactivity test results and the 28 days relative compressive strengths, how reactivity threshold values for classification of the chemical reactivity of SCMs could be proposed based on the R3 test results.
EFEK NITROCARBURIZING PADA MATERIAL LOW CARBON STEEL TERHADAP KETAHANAN KOROSI DAN KEKERASAN
Authors: Al Afghani Fajar , Hermawan Erwan , Shaleha Siti 
Published: May 2022

EFEK NITROCARBURIZING PADA MATERIAL LOW CARBON STEEL TERHADAP KETAHANAN KOROSI DAN KEKERASAN. Penggunaan baja saat ini mengalami pertumbuhan yang cukup pesat. Material baja karbon rendah banyak digunakan pada fasilitas di Instalasi Radiometalurgi, BATAN, terutama untuk komponen struktur konveyor, rantai, gerigi dan sebagainya. Penggunaannya yang semakin masif sehingga berbagai macam perkembangan pada material baja dilakukan. Salah satunya adalah dengan meningkatkan kualitas baja agar dapat digunakan dalam jangka waktu yang lama. Salah satu metode yang dapat digunakan untuk meningkatkan kualitas baja adalah dengan proses nitrokarburasi. Penelitian ini berfokus pada pengaruh proses nitrocarburizing terhadap laju korosi. Proses nitrocarburizing dilakukan pada beberapa sampel dengan temperatur yang berbeda dan gas yang sama. Peningkatan temperatur pada proses nitrocarburizing menghasilkan permukaan spesimen yang lebih keras. Peningkatan kekerasan diperoleh berdasarkan perbedaan temperatur yang meningkat dari 192 HV untuk sampel sebelum dinitrocarburizing menjadi 793 HV untuk sampel nitrocaburizing 450 ºC. Selain itu ketahanan korosi meningkat dengan meningkatnya temperatur nitrocarburizing. Proses nitrocarburizing menyebabkan difusi atom-atom C dan N sehingga membentuk compound layer, diffusion layer, dan transition layer yang terdiri dari lapisan ε-Fe2-3N, γ’- Fe4N, Fe2(N, C)1-z menjadikan lapisan permukaan material menjadi keras dan resistan terhadap korosi. Kata Kunci: Nitrocarburizing , korosi, kekerasan, low carbon steel
POLIFONIA E MEMÓRIA A PARTIR DO FEED RSS: A PERENIDADE DO PODCAST DA “MENSAGEM DO DIA”
Authors: Ferreira Junior José , Carneiro dos Santos Márcio , Lima de Sousa Jefferson Saylon 
Published: May 2022

Objetiva-se debater a polifonia no podcast e o surgimento de um espaço para manter a tradição das mensagens de otimismo. Para a discussão sobre memória e mídia se utiliza como corpus o podcast “Mensagem do Dia” da Rádio Mirante AM (São Luís/MA), na voz do radialista Roberto Fernandes, vítima da Covid-19 em 2020. Com o potencial para consumo, advindo do surgimento do podcast no ciberespaço, em especial a funcionalidade do Feed RSS, destaca-se a relevância do conceito de polifonia, na sua matriz referenciada pelo pensamento de Mikhail Bakhtin, problematizando-se a categoria mediante a possibilidade de uma memória construída a partir dos meios de comunicação com suas interfaces em dispositivos digitais. Adota-se a metodologia de análise pragmática da narrativa em diálogo com a categoria de performance de Paul Zumthor. Na parte final, sinaliza-se para um cenário tradutório das narrativas e práticas radiofônicas a partir do podcast como documento.
Epidemiologia de pacientes com câncer colorretal submetidos a tratamento cirúrgico em hospital público de referência
Authors: Girardon Dener Tambara , Jacobi Luciane Flores , Moraes Anaelena Bragança de 
Published: May 2022

Introdução: o câncer de cólon e reto (CCR) compreende os tumores malignos do intestino grosso e anorretal sendo a terceira neoplasia com mortes no mundo.Objetivos: avaliar informações sobre pacientes submetidos à colectomia e retossigmoidectomia por CCR em Hospital Universitário do Rio Grande do Sul em cinco anos. Materiais e métodos: estudo transversal, descritivo com dados de prontuários.Resultados: foram realizadas 224 cirurgias de colectomia e retossigmoidectomia em pacientes portadores de CCR, sendo a maioria (52,7%) do sexo feminino. A média de idade dos pacientes foi de 63,2 anos. A maioria (89,3%) tinham adenocarcinoma sendo 64,3% acometidos no retossigmoide e 24,6% no cólon direito. A retossigmoidectomia foi realizada em 63,8% dos pacientes. Com relação aos tempos autodeclarado dos sintomas, do diagnóstico ao tratamento cirúrgico, de internação hospitalar e do diagnóstico ao tratamento relacionado ao estadiamento não houve melhora nos índices do serviço, pelo contrário, o tempo entre o diagnóstico e a cirurgia e de internação até a cirurgia aumentaram. Quanto ao estadiamento 42,4% foram classificados em estadiamento III ou IV.Conclusões: o CCR é uma patologia com potencial índice de cura, desde que ocorra diagnóstico precoce. Neste estudo o estadiamento e os tempos avaliados são preocupantes e necessitam ser avaliados.
Ocorrência de sintomas depressivos e de ansiedade em fibromiálgicos
Authors: Toledo Cleber Vernillo de , Antunes Mateus Dias , Nishida Fernanda Shizue , Oliveira Leonardo Pestillo de 
Published: May 2022

Introdução: A Fibromialgia (FM) é classificada como uma síndrome reumática clínica comumente associada a sítios dolorosos com alta sensibilidade à dor quando friccionados (tender points), e por fortes dores musculoesquelética difusa e crônica. Entre as comorbidades estão a depressão e os sintomas de ansiedade. Objetivo: investigar sintomas de ansiedade e depressão em indivíduos com FM participantes da página do facebook “Grupo de Apoio a Portadores de FM”. Materiais e métodos: Trata-se de um estudo descritivo com participantes da página do facebook “Grupo de Apoio a Portadores de Fibromialgia”. Foram aplicados os testes Inventário de Depressão de Beck e a Escala Hamilton de Ansiedade. A estatística descritiva foi utilizada para análise de variáveis. Resutados: A amostra de estudo foi composta por 132 indivíduos com FM. Os resultados obtidos mostram uma alta prevalência de sintomas depressivos (68,1%) em portadores de FM. Os indivídus possuem sintomas de ansiedade com intensidade média alta (29,8±11,8). Conclusões: Considerando a FM e suas comorbidades resultantes e as dores musculoesquelética difusa que atrapalham a qualidade de vida dos portadores de FM, foram grandes o número de fibromiálgicos que desenvolvem sintomas depressivos e de ansiedade.
Think Tanks on Cultural Studies: Tribute to João Claudio Todorov
Authors: Vasconcelos Laércia Abreu , Malott Maria E. , Glenn Sigrid S. , Tourinho Emmanuel Zagury , Andery Maria Amalia Pie Abib 
Published: May 2022

This essay is dedicated to João Claudio Todorov (1941-2021). It focuses on the history of the Think Tanks on cultural studies from a culturo-behavioral science perspective. Todorov first conceived the idea of creating a Think Tank on Cultural Studies (TTCS). He organized the first one with Maria Malott in 2005 in Campinas, São Paulo. Occurring simultaneously with the XIV Brazilian Meeting of Psychology and Behavioral Medicine, there was a significant number of research presentations focused on cultural selection. The think tank focused on the concept of metacontingency, and its implications for research. The event counted on the presence of former editors of the Journal of the Experimental Analysis of Behavior. Think Tank 1 (TTCS1) inspired the organization of six additional think tanks, where Todorov always played a key role. Moreover, Todorov promoted the coordination with researchers from different higher education institutions, resulting in presentations at national and international scientific conferences, and joint publications. The most recent think tank, (TTCS7) took place in 2021 online due to the limitations from the Covid-19 pandemic, when Professor João Claudio Todorov attended for the last time.Keywords: Think Tank on Cultural Studies, Metacontingency, Macrocontingency, João Claudio Todorov.
Associative role of polymorphism of the РТРN22 (C1858T) gene in the development of hypertension in patients with the rheumatoid arthritis
Authors: Nikulina S. Yu. , Chernova A. A. , Tolstokorova Yu. A. , Varavko Yu. O. 
Published: May 2022

Objective. To assess the role of polymorphism of PTPN22 (C1858T) gebe in the development of hypertension (TNH) in patients with the rheumatoid arthritis (RA).Design and methods. We examined 202 patients with RA, we identified the following groups: patients with RA without HTN was identified (n = 53; 26%); patients with RA in association with HTN (n = 95; 47%), as well as patients with HTN without RA (n = 54; 27%). Healthy volunteers (n = 205) were also divided into 3 groups comparable by age, sex and size with the main groups. We applied clinical, laboratory, instrumental and molecular genetic methodsDNA isolation was performed by the standard phenol-chloroform method. Genotyping by the PTPN22 gene was carried out by the PCR-PDRF analysis method (polymerase chain reaction — polymorphism of the length of restriction fragments). PCR was performed with a set of primers to the corresponding areas of the genome. PCR products were analyzed by electrophoresis in a 4% polyacrylamide gel followed by staining with ethidium bromide.Results. The TT homozygous genotype and the T allele of the С1858Т gene polymorphism PTPN22 were predominant in the RA group and RA + HTN group compared to controls. The risk of RA without HTN is 1,7 fold higher in the TT carriers of the PTPN22 gene genotype, compared to CC and CT genotype carriers. Allele T was significantly more common in the group of patients with RA without HTN than in control group 1 [OR = 1,521 (95% confidence interval 1,0–2,324); р < 0,05]. A similar distribution of genotypes and alleles is seen in the group of RA patients in association with HTN compared to control group 2. No significant difference was found in the group of patients with HTN without RA compared to control group 3.Conclusions. Our study indicates that the homozygous TT genotype and the C1858T polymorphism T allele of the PTPN22 gene are predictors of RA development alone and in association with HTN.
ANALISIS SPASIAL KETERKAITAN PEREKONOMIAN WILAYAH DAN PENDAPATAN DAERAH DI INDONESIA DAN FILIPINA
Authors: Yunitasari Duwi , Firdaus Ahmad 
Published: May 2022

Indonesia and the Philippines are agrarian island countries, where there are spatial linkages which can be seen from the value of Gross Regional Domestic Product (GRDP) of the two countries. This study aims to analyze how the spatial dependencies of GRDP between provinces in Indonesia and between regions in the Philippines. In addition, it also aims to see the influence of the Government’s Original Local Revenue (PAD) on GRDP. The analytical tool used in this study is Moran's I, Lagrange Multiplier (LM) Test, Ordinary Least Square, Spatial Autoregressive Model (SAR), and Spatial Error Model (SEM) using Geoda software. The results of the analysis show that there is spatial dependencies in the two countries with clustered patterns, in which if the GRDP in the study area increases, it will increase the GRDP value in the surrounding area or those in direct contact. Based on the results of the analysis, the SAR model is the best model because it can be used to model economic growth in Indonesia and the Philippines. The results of modeling between provinces in Indonesia show that PAD has a significant effect on GRDP. The results of inter-provincial modeling in Indonesia show that PAD has a significant influence on GRDP. The same thing is also seen in the results of modeling between regions in the Philippines, which also shows that PAD has a significant influence on GRDP.
Keywords: GRDP, LM, Moran’s I, SAR, Spatial Dependencies
ANALISIS ADOPSI PENERIMAAN TEKNOLOGI INFORMASI OLEH USAHA MIKRO, KECIL, DAN MENENGAH DI KECAMATAN PANTI KABUPATEN JEMBER
Authors: Samsuryaningrum Ira Puspitadewi , Rahayu Jekti 
Published: May 2022

This study examines the effect of perceived usefulness and perceived ease of use on behavioral intention to use and actual use of information technology in Micro, Small, and Medium Enterprises (MSMEs). The sample of this study consisted of 40 respondents as the owners of MSMEs in Panti District, Jember Regency, which was taken by accidental sampling technique. SEM analysis was used to analyze research data. The results showed that perceived usefulness and perceived ease of use have significant effects on behavioral intention to use information technology. Perceived usefulness and perceived ease of use significantly affect the actual use of information technology. Results also showed that behavioral intention to use has a significant effect on the actual use of information technology. However, perceived usefulness through behavioral intention to use and perceived ease of use through behavioral intention to use did not significantly affect the actual use of information technology at MSME in Panti District, Jember Regency.
Keywords: actual use, behavioral intention to use, e-commerce, perceived ease of use, perceived usefulness
Pengaruh Pengalaman Pelanggan, Kesadaran Merek dan Kepuasaan Pelanggan Terhadap Loyalitas Pelanggan pada Ella Skin Care di Cabang Gentan
Authors: Setiawati Leedi , Susanti Ari 
Published: May 2022

The purpose of this study was to determine and analyze customer experience, brand awareness and customer satisfaction with ella skin care loyalty at the gentan branch. The population in this study is customer ella skin care. The sample in this study was 100 people with data collection techniques using questionnaires. Hypothesis testing using multiple linear regression analysis then the data is processed with SPSS 20 program. The results of this study indicate that customer experience does not have a significant effect on loyalty. Brand awareness and customer satisfaction have a significant effect on customer loyalty.
Keywords: Customer Experience, Brand Awareness, Customer Satisfaction, Customer Loyalty
La protección contra el despido y otras consecuencias desfavorables
Authors: Dormido Abril Julia 
Published: May 2022

La Directiva (UE) 2019/1158 establece la obligación de que los Estados miembros adopten las medidas que sean necesarias para prohibir el despido y cualquier preparación de éste cuando los trabajadores quieran hacer efectivos los derechos reconocidos en los diferentes ordenamientos jurídicos con relación a la conciliación de la vida laboral y familiar. Se trata de establecer mecanismos de protección específicos contra las represaliasque pueda emprender la empresa desde el momento en el que se solicitan o se disfrutan por parte de cualquiera de los progenitores los permisos relativos al ejercicio corresponsable de los derechos de la vida familiar y laboral.
Sin duda, el reparto equitativo de las cargas familiares es un instrumento que fomenta la igualdad real y efectiva entre ambos géneros, por lo que, resulta imprescindible que se establezcan en la legislación nacional cuáles son las consecuencias que tendrá que asumir laempresa que haya actuado de forma ilícita. Nos referimos, por tanto, a la imposición de unas sanciones que deberán tener una entidad suficiente como para ser efectivas y disuasorias, de manera que la parte empleadora no trate de despedir a las trabajadoras y los trabajadoresque pretendan solicitar un permiso de conciliación para atender a un familiar que dependa de ellos o necesite de cuidados, por cualquiera de las circunstancias especialmente protegidas en la normativa europea.
Loading Capacity of Water Pollution from Cage Aquaculture in South Kalimantan Rivers
Authors: Herliwati Herliwati , Rahman Mijani 
Published: May 2022

Decreasing of water quality and exceeding the loading capacity of water pollution are the main causes of the high mortality of cage aquaculture along the river in South Kalimantan province. The research objective was to analyze the river water quality profile, and to evaluate the loading capacity of water pollution around the cage aquaculture. The observations were made at 3 points (upstream, middle and downstream) along Harus river where is the center for the development of cage aquaculture in Banua Lawas District, Tabalong Regency. On each of these points, measurement of physico-chemical parameters of water and flow rates were carried out. Measurement and data collection were performed twice with intervals between measurements for 30 days. Water quality parameters analyzed were water temperature, pH, TSS, NH<sub>3</sub>-N, NO<sub>3</sub>-N, PO<sub>4</sub>-P, BOD, COD, and DO. Based the eight water quality parameters measured, there were three parameters that tend to exceeding the loading capacity of water pollution on all the river segments, namely PO<sub>4</sub>-P, (at middle = 16 kg day<sup>-1</sup>, and downstream = 459 kg day<sup>-1</sup>), BOD (at upstream = 301 kg day<sup>-1</sup>, middle = 547 kg day<sup>-1</sup>, and downstream = 2,086 kg day<sup>-1</sup>) and COD (at upstream = 521 kg day<sup>-1</sup>, middle = 380 kg day<sup>-1</sup> and downstream = 1,249 kg day<sup>-1</sup>). Exceeding the load capacity of BOD and COD were prone to cause depletion of DO in the river in which can potentially cause massive fish mortality.
The Study of Superior Varieties and New Plant Types of Rice on Various Organic Cropping Systems in Tidal Land
Authors: Safi'e Muhammad , Susanti Hilda , Adriani Dewi Erika 
Published: May 2022

<div><p><strong> </strong></p></div><div><p>Increasing rice production with the use of high-yielding varieties and proper plant spacing must consider the environmental aspect. Organic agriculture is an effort to accelerate the cultivation techniques with environmental health, in addition, the research site is a tidal land that has been cultivating rice organically since 2009. The research aimed to study the growth and yield of superior varieties and new plant type of rice on various cropping systems in tidal land. The research was carried out at the Laboratory of Center for Protection of Food Crops and Horticulture, Sungai Tabuk District, Banjar Regency. The experimental design was a split-plot with three replications. The main plot were s1 = Tile System, s2 = Legowo System 2:1, s3 = Legowo System 8:1 cropping systems and subplots were v1= Ciherang, v2= Mekongga, v3= IPB Batola 6R, v4= IPB 3S varieties. The experimental unit was a plot with a size of 10 m<sup>2</sup>. The results showed that there was no interaction between cropping systems and rice varieties. The main plot of cropping system Legowo 2:1 showed the best percentage of filled grain per panicle (87%). Sub-plot of rice varieties affected some plant growth and yield variables. Superior varieties <em>Ciherang</em> and <em>Mekongga</em> had more tillers and panicles per clump. The new plant type varieties showed a greater number of grains per panicle and tended to have a better percentage of filled grains per panicle and a weight of 1,000 grains.</p></div>