bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Brief Review on Mathematical Tools Applicable to Quantum Computing for Modelling and Optimization Problems in Engineering
Authors: Mahmoudi Yousra , Zioui Nadjet , Belbachir Hacène , Tadjine Mohamed , Rezgui Abdelmounaam 
Published: November 2022

Since its emergence, quantum computing has enabled a wide spectrum of new possibilities and advantages, including its efficiency in accelerating computational processes exponentially. This has directed much research towards completely novel ways of solving a wide variety of engineering problems, especially through describing quantum versions of many mathematical tools such as Fourier and Laplace transforms, differential equations, systems of linear equations, and optimization techniques, among others. Exploration and development in this direction will revolutionize the world of engineering. In this manuscript, we review the state of the art of these emerging techniques from the perspective of quantum computer development and performance optimization, with a focus on the most common mathematical tools that support engineering applications. This review focuses on the application of these mathematical tools to quantum computer development and performance improvement/optimization. It also identifies the challenges and limitations related to the exploitation of quantum computing and outlines the main opportunities for future contributions. This review aims at offering a valuable reference for researchers in fields of engineering that are likely to turn to quantum computing for solutions. Doi: 10.28991/ESJ-2023-07-01-020 Full Text: PDF
TROMBOSIS VENA DALAM
Authors: Arum Ima Arum 
Published: November 2022

Penyakit tromboembolik menunjukkan hubungan dengan trombosis yaitu proses pembentukan bekuan darah (trombus) dan resiko emboli. Trombosis Vena Dalam (TVD) adalah kondisi dimana terbentuk bekuan dalam vena sekunder / vena dalam oleh karena inflamasi /trauma dinding vena atau karena obstruksi vena sebagian. Penyebab utama trombosis vena belum jelas, tetapi ada tiga kelompok faktor pendukung yang dianggap berperan penting dalam pembentukannya yang dikenal sebagai TRIAS VIRCHOW yaitu abnormalitas aliran darah, dinding pembuluh darah dan komponen factor koagulasi. Standar baku emas untuk diagnosis TVD adalah venografi intarvena, di mana bahan kontras diinjeksikan pada vena kemudian difoto rontgen untuk melihat di mana terdapat obstruksi vena. Pemeriksaan ini invasif sehingga jarang dilakukan.Diagnosis yang didasarkan pada temuan fisik saja tidak dapt diandalkan, sedangkan untuk penatalaksanaan TVD secara optimal, perlu diagnosis yang obyektif. Guna mempermudah pendekatan diagnosis, digunakan sistem skoring untuk menentukan besarnya kemungkinan diagnosis klinik serta pemeriksaan laboratorium, Compression ultrasonography, dan venografi, yang dijadikan bukti diagnosis obyektif.
Kata kunci : trombosis vena dalam, skor wells
Penerapan Zahir Accounting Versi 6 Untuk Pengolahan Data Keuangan (Studi Kasus: Bi Petshop)
Authors: Frilya Nanda , Utami Lila Dini , Johan Windy 
Published: November 2022

Bi Petshop bergerak dalam bidang perdagangan dan jasa, yaitu penjualan Makanan, Aksesories, dan Salon kecantikan bagi hewan peliharaan. Laporan Keuangan Bi Petshop masih menggunakan sistem pencatatan dan pengelolahan data keuangan secara manual sehingga menimbulkan kesalahan dalam proses penginputan transaksi keuangan, keterlambatan dalam penyimpanan data laporan keuangan perusahaan, dan mengakibatkan terjadinya kesalahan dalam proses perhitungan laporan keuangan perusahaan. Maka pada masa ini dibutuhkan sistem yang terkomputerisasi untuk semua proses akuntansi manual, penulis melakukan pengamatan langsung untuk memperoleh data-data dalam menyusun penelitian ini dan mewawancarai pemilik Bi Petshop untuk membantu dalam proses pencatatan transaksi dan pembuatan laporan keuangan. Maka dari itu, software akuntansi Zahir Accounting Versi 6.0 dapat menjadi solusi yang baik untuk pengelolahan data keuangan pada Bi Petshop agar dapat membuat laporan keuangan serta penyajian laporan keuangan menjadi lebih jelas, efektif dan efisien dengan bertujuan mempermudah dalam proses pengelolahan data akuntansi, menganalisa laporan keuangan dengan baik dan benar
ВИКОРИСТАННЯ МЕНТАЛЬНИХ КАРТ НА НАВЧАЛЬНИХ ЗАНЯТТЯХ З ХІМІЇ
Authors: Гиря Олексій 
Published: November 2022

The article updates the problem of using mental maps in the educational process of a general secondary education institution, in particular, in chemistry classes.
The purpose of the article is to substantiate the expediency of using mental maps in chemistry classes in a general secondary education institution. In the course of writing the article, such theoretical research methods as analysis, synthesis, modeling, as well as empirical methods - a pedagogical experiment were used to test the effectiveness of using mental maps in the educationalprocess of chemistry.
The article characterizes the possibilities of using mental maps in the process of planning the activity of a chemistry teacher, in the process of forming integrated knowledge of students in chemistry lessons, as well as their application in extracurricular work of the student, in particular, in the process of creating individual and group projects. Intelligence maps help to organize, systematizescientific information, group scientific data, opinions, find new ideas, plan work, evaluate its scope, summarize scientific achievements in this field of research.
The results of the empirical study proved that mental maps have a positive effect on the formation of the subject competence of high school students in all the main components. The need to improve the possibilities of using mental maps in relation to such important components of training as the identification of correct judgments and conclusions, as well as the formation of a reflective component of training, was established.
It was concluded that mental maps in education are a modern and compact way of processing educational material, which makes the chemistry lesson interesting and informative, and also allows students to learn the material better. The use of mind mapping technology also opens up a range of opportunities for the development of the teacher's creative potential.
УДОСКОНАЛЕННЯ ЛАБОРАТОРНОГО ПРАКТИКУМУ З ОРГАНІЧНОЇ ХІМІЇ ВІДПОВІДНО ДО УМОВ СЬОГОДЕННЯ
Authors: Підгурська Вікторія , Сакалова Галина 
Published: November 2022

The purpose of the article is to analyze the features of conducting a small laboratory workshop as a means of studying the course of organic chemistry without the use of reagents included in the list of narcotic drugs, psychotropic substances andprecursors.
During the writing of the article, such methods of scientific research as analysis, synthesis, comparison, generalization were used - to find out the state of solving the researched problem in the theory and methodology of teaching chemistry, to determine the theoretical foundations of the research, as well as a chemical experiment - to conduct experimental research and proving the effectiveness of theoretical assumptions.
Based on the analysis of literary sources, the tasks, main functions and requirements for a chemical experiment in the process of learning organic chemistry are determined. It has been found that the problem of using a chemical experiment tostudy the basic principles of the structure of organic compounds, methods of their synthesis and properties requires further research in order to adapt the methodology of conducting experiments to the conditions under which the use of precursors andtoxic substances is limited. The greatest attention was focused on methodological aspects of reproduction and description of experiments on the oxidation of organic compounds, since most of such experiments had to be adapted to the conditions underwhich the use of potassium permanganate is prohibited.
The results of the conducted research showed the possibility of adapting the methods of a small laboratory workshop in organic chemistry to the conditions under which the use of precursors and toxic substances is excluded. As a substitute forpotassium permanganate solution, potassium chromate and potassium dichromate solutions were used and a positive result was obtained. Developed recommendations can be used for research and conducting laboratory work in laboratories ofeducational institutions.
The Invisible Co-Worker Among Us: Understanding Childhood Trauma and Workplace Well-Being
Authors: Neilio R Michael , Kristen A. Toohill  , Ryan T.W. McCreedy  , Aprille F. Young  , Leanne M. Tortez  
Published: November 2022

This work intended to investigate potential correlations between past experienced personal trauma to the everyday experience of workplace well-being. The authors explored traumatic childhood stories using the Philadelphia extended version of the original Adverse Childhood Experiences (ACEs) survey. Connections to these experiences were sought in a broad range of populations using snowball sampling. Participants (N = 406) were asked to answer the ACEs survey and questions on their current perception of workplace well-being using the Eudaimonic Workplace Well-Being Scale (EWWS). Results indicated a strong correlation that was statistically significant. An increase in the number of ACEs aligned with a lower perception of well-being within the workplace. This is the first study of its kind to connect clinical childhood trauma experience with current adult workplace experience of well-being. Findings suggest enhanced focus should be placed on engaged awareness and action-oriented treatment of mental health in the workplace.
Establishment and application of loop-mediated isothermal amplification coupled with nanoparticle-based lateral flow biosensor (LAMP-LFB) for visual and rapid diagnosis of Candida albicans in clinical samples
Authors: Wang Yu , Zhao Xue , Zhou Yuhong , Lu Jingrun , Yu Honglan , Li Shijun 
Published: November 2022

Candida albicans is an opportunistic pathogenic yeast that predominantly causes invasive candidiasis. Conventional methods for detecting Candida species are costly, take 3–5 days, and require skilled technicians. Rapid pathogen identification is important in managing invasive candidiasis infection. Here, a novel molecular diagnostic assay termed loop-mediated isothermal amplification combined with nanoparticles-based lateral flow biosensor (LAMP-LFB) was developed for C. albicans rapid detection. A set of six primers was designed based on the C. albicans species-specific internal transcribed spacer 2 (ITS2) gene. The C. albicans-LAMP results were visually reported by LFB within 2 min. Various fungal strains representing Candida species, as well as several Gram-negative and Gram-positive bacterial species, were used to determine the analytical sensitivity and specificity of the assay. The optimal LAMP conditions were 64 °C for 40 min, with a sensitivity of 1 fg of genomic DNA template from C. albicans pure cultures. No cross-reactions were obtained with non-albicans strains. Thus, the analytical specificity of the LAMP-LFB assay was 100%. The entire procedure could be completed within 85 min, including specimen processing (40 min), isothermal reaction (40 min), and result reporting (within 2 min). In 330 clinical samples (including 30 whole blood, 100 middle segment urine, and 200 sputum samples), all C. albicans-positive (62/330) samples were identified by LAMP-LFB assay, and the diagnostic accuracy was 100% when compared to the traditional clinical cultural-based methods. Thus, this assay can be used as a diagnostic tool for the rapid, accurate, sensitive, low-cost and specific detection of C. albicans strains, especially in resource-limited settings.
Impact of WTAP in small HCC and paired adjacent non-neoplastic liver tissue on recurrence: A cohort study with external extension analysis
Authors: Duan Jin-Ling , Deng Min-Hua , Xiang Zhi-Cheng , Hu Jin-Long , Qu Chun-Hua , Zhu Tian-Chen , Xu Ming-Xing , Chen Jie-Wei , Xie Juan-Juan , Xie Dan , Cai Mu-Yan , Li Mei , Liang Hu 
Published: November 2022

Background: To evaluate prognostic value of WTAP levels in tumor and paired adjacent non-neoplastic liver tissues (PANLT) for cases of hepatitis B virus (HBV)-positive Asian small hepatocellular carcinoma (sHCC) patients who received curative partial hepatectomy.Method: The investigation with two external cohorts were included. Associations between hazard risk of recurrence and continuous WTAP levels were investigated with restricted cubic spline models. Cox and inverse probability weighting models were established for survival analysis. Based on interaction effects, further stratification analysis was performed. Landmark analysis was employed to analyze cases of late recurrence. Finally, sensitivity analysis was performed to assess unmeasured confounders.Findings: In an investigation cohort of 307 patients, restricted cubic spline models indicated that hazard risk of recurrence increases with elevated WTAP levels for sHCC and PANLT. However, using Cox and inverse probability weighting models, no significant differences were observed in recurrence-free survival (RFS) between groups with different WTAP levels in sHCC. Multivariate analysis showed that patients with high PANLT WTAP levels had significantly worse RFS (HR 1.567, 95% CI 1.065–2.307; p = 0.023). Based on the significant interaction effect between WTAP levels in sHCC and PANLT, stratification analysis revealed that recurrence risk is more pronounced in patients with high WTAP levels in both PANLT and sHCC. Landmark analysis showed that late recurrence was more likely to occur in patients with high PANLT WTAP levels (HR 2.058, 95% CI 1.113–3.805; p = 0.021). Moreover, the detrimental effects of elevated PANLT WTAP levels on RFS were validated with two external cohorts. Sensitivity analysis confirmed the robustness of results.Conclusion: Increased PANLT WTAP expression levels independently predict high recurrence risk in HBV-positive Asian sHCC patients. Both tumor tissues and PANLT need to be considered together in future clinical practice to obtain a more comprehensive and accurate evaluation for recurrence risk.
Recent advances in in silico design and characterization of superalkali-based materials and their potential applications: A review
Authors: Pandey Sarvesh Kumar , Arunan Elangannan , Das Ratnesh , Roy Atish , Mishra Arunesh Kumar 
Published: November 2022

In the advancement of novel materials, chemistry plays a vital role in developing the realm where we survive. Superalkalis are a group of clusters/molecules having lower ionization potentials (IPs) than that of the cesium atom (3.89 eV) and thus, show excellent reducing properties. However, the chemical industry and material science both heavily rely on such reducing substances; an in silico approach-based design and characterization of superalkalis have been the focus of ongoing studies in this area along with their potential applications. However, although superalkalis have been substantially sophisticated materials over the past couple of decades, there is still room for enumeration of the recent progress going on in various interesting species using computational experiments. In this review, the recent developments in designing/modeling and characterization (theoretically) of a variety of superalkali-based materials have been summarized along with their potential applications. Theoretically acquired properties of some novel superalkali cations (Li3+) and C6Li6 species, etc. for capturing and storing CO2/N2 molecules have been unveiled in this report. Additionally, this report unravels the first-order polarizability-based nonlinear optical (NLO) response features of numerous computationally designed novel superalkali-based materials, for instance, fullerene-like mixed-superalkali-doped B12N12 and B12P12 nanoclusters with good UV transparency and mixed-valent superalkali-based CaN3Ca (a high-sensitivity alkali-earth-based aromatic multi-state NLO molecular switch, and lead-founded halide perovskites designed by incorporating superalkalis, supersalts, and so on) which can indeed be used as a new kind of electronic nanodevice used in designing hi-tech NLO materials. Understanding the mere interactions of alkalides in the gas and liquid phases and the potential to influence how such systems can be extended and applied in the future are also highlighted in this survey. In addition to offering an overview of this research area, it is expected that this review will also provide new insights into the possibility of expanding both the experimental synthesis and the practical use of superalkalis and their related species. Superalkalis present the intriguing possibility of acting as cutting-edge construction blocks of nanomaterials with highly modifiable features that may be utilized for a wide-ranging prospective application.
Oxidative stress markers-driven prognostic model to predict post-discharge mortality in heart failure with reduced ejection fraction
Authors: Gtif Imen , Abdelhedi Rania , Ouarda Wael , Bouzid Fériel , Charfeddine Salma , Zouari Fatma , Abid Leila , Rebai Ahmed , Kharrat Najla 
Published: November 2022

BackgroundCurrent predictive models based on biomarkers reflective of different pathways of heart failure with reduced ejection fraction (HFrEF) pathogenesis constitute a useful tool for predicting death risk among HFrEF patients. The purpose of the study was to develop a new predictive model for post-discharge mortality risk among HFrEF patients, based on a combination of clinical patients’ characteristics, N-terminal pro-B-type Natriuretic peptide (NT-proBNP) and oxidative stress markers as a potentially valuable tool for routine clinical practice.Methods116 patients with stable HFrEF were recruited in a prospective single-center study. Plasma levels of NT-proBNP and oxidative stress markers [superoxide dismutase (SOD), glutathione peroxidase (GPX), uric acid (UA), total bilirubin (TB), gamma-glutamyl transferase (GGT) and total antioxidant capacity (TAC)] were measured in the stable predischarge condition. Generalized linear model (GLM), random forest and extreme gradient boosting models were developed to predict post-discharge mortality risk using clinical and laboratory data. Through comprehensive evaluation, the most performant model was selected.ResultsDuring a median follow-up of 525 days (7–930), 33 (28%) patients died. Among the three created models, the GLM presented the best performance for post-discharge death prediction in HFrEF. The predictors included in the GLM model were age, female sex, beta blockers, NT-proBNP, left ventricular ejection fraction (LVEF), TAC levels, admission systolic blood pressure (SBP), angiotensin-converting enzyme inhibitors/angiotensin receptor II blockers (ACEI/ARBs) and UA levels. Our model had a good discriminatory power for post-discharge mortality [The area under the curve (AUC) = 74.5%]. Based on the retained model, an online calculator was developed to allow the identification of patients with heightened post-discharge death risk.ConclusionIn conclusion, we created a new and simple tool that may allow the identification of patients at heightened post-discharge mortality risk and could assist the treatment decision-making.
Potential metabolomic biomarkers for the identification and diagnosis of type A acute aortic dissection in patients with hypertension
Authors: Hao Xiao-Bin , Han Yue , Ni Er-Ru , Ye Ming-Cai , Li Gang , Wu Xi-Jie , Qiang Hai-Feng , Zhao Jun 
Published: November 2022

ObjectivesMost patients with acute aortic dissection (AAD) have a history of hypertension. Diagnosis of AAD in patients with hypertension at an early stage is complicated and challenging. This study aimed to explore the distinctive metabolic changes in plasma samples of AAD patients with hypertension and patients with hypertension only and provide early identification and diagnosis of AAD in patients with hypertension.Materials and methodsWe collected blood samples from 20 patients with type A AAD and hypertension admitted to the emergency department and physically examined other 20 patients with hypertension as controls. The plasma metabolomic profiles of these patients were determined using untargeted metabolomics with ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry.ResultsA total of 38 metabolites that differed between the AAD and hypertension groups were screened. In the positive ion mode, 12 metabolites were different between the two groups, and in the negative ion mode, 26 metabolites were different. Among the 26 different metabolites detected by the negative ion mode, 21 were significantly upregulated and five were downregulated in patients with AAD compared to patients with hypertension. Moreover, five metabolites were upregulated and seven were significantly downregulated in patients with AAD compared to those with hypertension, as detected by the positive ion mode. The metabolites differentially expressed in AAD were mainly involved in lipid metabolism (fatty acid biosynthesis, biosynthesis of unsaturated fatty acids, and linoleic acid metabolism), carbohydrate metabolism (galactose, fructose, and mannose metabolisms), and membrane transport (ATP-binding cassette transporters). Interestingly, plasma hydrocortisone and dimethylglycine concentrations were significantly increased in patients with type A AAD, with the highest area under the curve value (AUC = 0.9325 or 0.9200, respectively) tested by the receiver operating characteristic curve analysis.ConclusionThis study provides possible metabolic markers for the early clinical diagnosis of AAD in patients with hypertension.
Inferior vena cava filters in pregnancy: Safe or sorry?
Authors: Bistervels Ingrid M. , Buchmüller Andrea , Tardy Bernard 
Published: November 2022

BackgroundPotential hazards of vena cava filters include migration, tilt, perforation, fracture, and in-filter thrombosis. Due to physiological changes during pregnancy, the incidence of these complications might be different in pregnant women.AimTo evaluate the use and safety of inferior vena cava filters in both women who had an inferior vena cava filter inserted during pregnancy, and in women who became pregnant with an inferior vena cava filterin situ.MethodsWe performed two searches in the literature using the keywords “vena cava filter”, “pregnancy” and “obstetrics”.ResultsThe literature search on women who had a filter inserted during pregnancy yielded 11 articles compiling data on 199 women. At least one filter complication was reported in 33/177 (19%) women and included in-filter thrombosis (n= 14), tilt (n= 6), migration (n= 5), perforation (n= 2), fracture (n= 3), misplacement (n= 1), air embolism (n= 1) and allergic reaction (n= 1). Two (1%) filter complications led to maternal deaths, of which at least one was directly associated with a filter insertion. Filter retrieval failed in 9/149 (6%) women. The search on women who became pregnant with a filterin situresulted in data on 21 pregnancies in 14 women, of which one (6%) was complicated by uterine trauma, intraperitoneal hemorrhage and fetal death caused by perforation of the inferior vena cava filter.ConclusionThe risks of filter complications in pregnancy are comparable to the nonpregnant population, but could lead to fetal or maternal death. Therefore, only in limited situations such as extensive thrombosis with a contraindication for anticoagulants, inferior vena filters should be considered in pregnant women.