bluuebunny/crossref_metadata_2025_split huggingface dataset:
Building and evolving a culture of excellence: a conceptual exploration
Authors: Provance Travis W. , Ramisetty Suresh Babu , Urick Michael Joseph , Wieczorkowski Kelly A. 
Published: January 2022

Purpose
The purpose of this paper is to conceptually explore building a culture of excellence from the ground up as well as evolving a current culture to one more focused on excellence.

Design/methodology/approach
This study reviewed extant research related to organizational cultures and cultures of excellence that have implications for building or evolving into these types of cultures.

Findings
The findings of this study suggest that the “people side” of organizations is crucial to forming a culture of excellence. Specific people-oriented considerations to forming such a culture include leveraging leaders and understanding other influences including diversity as well as external aspects. Changing culture must occur at the assumptions (and not just artifacts) level. Furthermore, there are many barriers to building a culture of excellence, many of which are also related to an organization’s people.

Research limitations/implications
A qualitative grounded theory approach whereby researchers asked organizational members to define “culture of excellence” could help build a clearer model for the formation of cultures of excellence. Quantitative approaches should also test how successful the influencers, noted in this study are in creating cultures of excellence. This study’s conceptual links between cultures of excellence and performance should also be tested empirically.

Practical implications
This paper provides practitioners insight into the importance of culture and considerations for how to change an organizational culture.

Social implications
This paper advocates for the importance of social considerations in the workplace regarding creating a culture of excellence.

Originality/value
To the best of the authors’ knowledge, this paper is the first that discusses creating a culture of excellence. Furthermore, it is one of only a handful of articles that links people to excellence.
How organisations can remove barriers to increase workforce collaboration
Authors: Watson Andrew 
Published: January 2022

Purpose
The purpose of this paper is to explore how organisations can remove the barriers that they are currently coming up against to increase their workforce collaboration. Playing a key role in workforce transformation, HR faces pressures to remove the barriers that stand in the way of effective collaboration and decision-making; and Andrew Watson explores in this piece the ways in which organisations can empower employees to take a more collaborative approach to work.

Design/methodology/approach
Drawing on Andrew’s extensive experience in HR, this is a thought led opinion piece.

Findings
The findings of the paper show that to empower employees to foster greater collaboration, organisations require a broader cultural shift in organisation. Although there are new challenges such as hybrid working models and siloed departments, Andrew’s paper reveals that to become a more collaborative workplace, employees need a platform that will allow them to come together and cultivate openness and transparency. Technology has the power to break down the communication barriers that stand in the way of effective ideas and knowledge sharing strategies. It can also help teams make incremental improvements quickly without having to wait for multiple approvals.

Originality/value
Drawing on Andrew’s extensive experience in HR to share insights.
Measuring tourism success: alternative considerations
Authors: Butler Richard 
Published: January 2022

PurposeThe study aims to explore the possibility of redefining success in tourism and measuring such a phenomenon by considering alternatives to economic factors, and to identify the ways such measurement could be implemented.Design/methodology/approachThe study reviews and explains current approaches to defining and measuring success in tourism in the literature, followed by identification of alternative factors which could be measured and the implications of such a change in approach.FindingsThere has been a long-standing emphasis and priority placed on measuring tourism at the national level with a focus on economic criteria, and this has been followed at regional and local levels. The result has been that success has become equated with volume, supporting the aim of continued growth in tourism. Such an approach and attitude mitigate against achieving or moving towards sustainability, and other measures are needed to avoid problems such as overtourism.Originality/valueThere has been little discussion of moving to a wider range of indicators of success in tourism, and the previous focus has been on economic criteria and competitiveness as shown by tourist numbers. This paper presents a discussion of an alternative approach, showing that tourism stakeholders from national to local levels need to redefine success as including factors such as community and environmental well-being and focus on a wider concept of success. Using existing data and organisations would enable measuring such concepts to be done without major change or greatly increased costs to agencies.
Stratigraphy and Zircon Provenance of a Late Paleoproterozoic Terrestrial Sequence underlying the Xiong'er Volcanics in the Southern North China Craton
Authors: SUN Fengbo , ZHENG Deshun , ZUO Pengfei , LIU Weiqing 
Published: January 2022

AbstractThe late Paleoproterozoic Dagushi Formation comprises a fluvial‐lacustrine succession and represents the initial fill of the Xiong'er Basin in the southern North China Craton. Employing integrated outcrop surveys and detrital zircon U‐Pb‐Hf dating, this study examines the provenance and depositional setting of the Dagushi Formation. Five major depositional facies, including braided channel, distributary channel, subaqueous stream/mouth bar, pro‐delta and shallow lake, were identified, based on lithofacies and associations. They were interpreted as representing a braided river delta‐lacustrine system. The ages of the last metamorphic event of the basement, covering volcanics and the youngest zircon together constrain a depositional age of ca. 1.79 Ga for the Dagushi Formation. Zircon age distributions reveal a provenance change from ca. 2.7–2.5 Ga rocks in the lower part, to ca. 2.3–1.9 Ga sources in the middle‐upper part of the Dagushi Formation. Considering the vertical sedimentology, this provenance change could be induced by the rising water‐level caused by a tectonic subsidence. The ca. 2.7–2.5 Ga zircons are suggested to be locally sourced from the late Neoarchean–Paleoproterozoic metamorphic basement. The northeast Zhongtiao Mts area (current co‐ordinates) is supposed to have appeared as a paleo‐uplift and served as a source area for the Paleoproterozoic grains. The Dagushi Formation records an early ‘underfilled’ stage of the Xiong'er Rift.
Seismic Imaging and 3D Architecture of Yongle Atoll of the Xisha Archipelago, South China Sea
Authors: WU Shiguo , ZHANG Hanyu , QIN Yongpeng , CHEN Wanli , LIU Gang , HAN Xiaohui 
Published: January 2022

AbstractYongle atoll in the Xisha (Paracel) Archipelago is an isolated carbonate platform developed on Precambrian metamorphic and Mesozoic volcanic rocks since the early Miocene. To identify the 3D stratigraphic architecture and evolution of this platform, 13 high‐resolution seismic profiles and shallow‐to‐deep water multi‐beam data were processed and analyzed to reveal seismic facies, sequence boundary reflectors, seismic units, and platform architecture. Nine types of seismic facies were recognized based on their geometry, which included seismic amplitude, continuity, and termination patterns; additionally, six reflections, i.e., Tg, T60, T50, T40, T30, and T20, were identified in the Cenozoic strata. Five seismic units, SQ1 (lower Miocene), SQ2 (middle Miocene), SQ3 (upper Miocene), SQ4 (Pliocene), and SQ5 (Quaternary), were identified from bottom to top across the platform. The platform grew rapidly in the middle Miocene and backstepped in the late Miocene–Pliocene. Here, we discuss the developmental characteristics and evolution of the Yongle Atoll, in combination with drilling wells, which can be divided into four stages: the initiation stage in the early Miocene, the flourishing stage in the middle Miocene, the partial‐drowning stage in the late Miocene–Pliocene, and modern atoll in the Quaternary.
Denosumab and invasive cervical root resorption: a case report
Authors: Beaumont S , Angel CM , Dawson S‐J 
Published: January 2022

AbstractThis case report describes an adverse side effect from long‐term denosumab therapy in a patient with metastatic breast cancer. The patient presented with extensive invasive cervical root resorption affecting most of her dentition. There were no other identified risk factors. As the treatment of breast cancer evolves leading to improved survival, and the number of cancer survivors increases, it is expected that dental practitioners will see a growing number of patients who are on long‐term denosumab. Comprehensive dental examinations including radiographs are warranted to identify unusual or unexpected findings such as invasive cervical root resorption. © 2022 Australian Dental Association
EAACI position paper on the clinical use of the bronchial allergen challenge: Unmet needs and research priorities
Authors: Agache Ioana , Antolin‐Amerigo Dario , de Blay Frederic , Boccabella Cristina , Caruso Cristiano , Chanez Pascal , Couto Mariana , Covar Ronina , Doan Serge , Fauquert Jean‐Luc , Gauvreau Gail , Gherasim Alina , Klimek Ludger , Lemiere Catherine , Nair Parameswaran , Ojanguren Iñigo , Peden David , Perez‐de‐Llano Luis , Pfaar Oliver , Rondon Carmen , Rukhazde Maia , Sastre Joaquin , Schulze Johannes , Silva Diana , Tarlo Susan , Toppila‐Salmi Sanna , Walusiak‐Skorupa Jolanta , Zielen Stefan , Eguiluz‐Gracia Ibon 
Published: January 2022

AbstractAllergic asthma (AA) is a common asthma phenotype, and its diagnosis requires both the demonstration of IgE‐sensitization to aeroallergens and the causative role of this sensitization as a major driver of asthma symptoms. Therefore, a bronchial allergen challenge (BAC) would be occasionally required to identify AA patients among atopic asthmatics. Nevertheless, BAC is usually considered a research tool only, with existing protocols being tailored to mild asthmatics and research needs (eg long washout period for inhaled corticosteroids). Consequently, existing BAC protocols are not designed to be performed in moderate‐to‐severe asthmatics or in clinical practice. The correct diagnosis of AA might help select patients for immunomodulatory therapies. Allergen sublingual immunotherapy is now registered and recommended for controlled or partially controlled patients with house dust mite‐driven AA and with FEV1 ≥ 70%. Allergen avoidance is costly and difficult to implement for the management of AA, so the proper selection of patients is also beneficial. In this position paper, the EAACI Task Force proposes a methodology for clinical BAC that would need to be validated in future studies. The clinical implementation of BAC could ultimately translate into a better phenotyping of asthmatics in real life, and into a more accurate selection of patients for long‐term and costly management pathways.
Importance of electromagnetic interactions between ICD and VAD devices—Mechanistic assessment
Authors: Schnegg Bruno , Robson Desiree , Fürholz Monika , Meredith Tom , Kessler Cassia , Baldinger Samuel H. , Hayward Christopher 
Published: January 2022

AbstractBackgroundImplanted cardioverter defibrillators (ICDs) and left ventricular assist devices (LVADs) are established interventions that prolong life in advanced heart failure, but their combination has not been demonstrated as beneficial. Electromagnetic interference (EMI) produced by a LVAD can preclude ICD interrogation with external programmers. We undertook a systematic evaluation of the LVAD–ICD interaction “in‐vitro” to clarify the extent of this interaction.MethodsUsing explanted ICDs and VADs in a mock physiological rig, we assessed interrogation and reprogramming of ICD devices in the presence of a running LVAD. When connectivity between the ICD programmer and the ICD failed, we attempted three different techniques to re‐establish connectivity: (1) Electromagnetic shielding of the ICD with a pseudo‐faraday cage; (2) altering the LVAD speed; and (3) increasing the distance between the VAD and the ICD.ResultsWe tested a total of 24 ICDs from different manufacturers in the presence of the Heartware (HW) and HeartMate 3 (HM3) LVADs. With HW, we only observed interaction with Biotronik ICD devices at very close range (0–6 cm). With HM3, only Medtronic ICD devices showed no interaction. Interactions could be mitigated by increasing the VAD–ICD distance.ConclusionsLVADs, notably the HM3, produce EMI that interferes with the communication between an ICD and its respective programmer. This may need to be considered when choosing the type of VAD to implant in patients with a previously implanted left‐sided ICD. The only safe way to regain connectivity is to increase the distance between the VAD and the ICD, with patients raising their arm above their head.
The regulatory mechanism between lysosomes and mitochondria in the aetiology of cardiovascular diseases
Authors: Zhao Mengxue , Lian Andrew , Zhong Li , Guo Rui 
Published: January 2022

AbstractCoordinated action among various organelles maintains cellular functions. For instance, mitochondria and lysosomes are the main organelles contributing to cellular metabolism and provide energy for cardiomyocyte contraction. They also provide essential signalling platforms in the cell that regulate many key processes such as autophagy, apoptosis, oxidative stress, inflammation and cell death. Often, abnormalities in mitochondrial or lysosomal structures and functions bring about cardiovascular diseases (CVDs). Although the communication between mitochondria and lysosomes throughout the cardiovascular system is intensely studied, the regulatory mechanisms have not been completely understood. Thus, we summarize the most recent studies related to mitochondria and lysosomes’ role in CVDs and their potential connections and communications under cardiac pathophysiological conditions. Further, we discuss limitations and future perspectives regarding diagnosis, therapeutic strategies and drug discovery in CVDs.
Acute pyelonephritis: Increased plasma membrane targeting of renal aquaporin‐2
Authors: Ernstsen Christina V. , Login Frédéric H. , Schelde Anne‐Sofie B. , Therkildsen Jacob R. , Møller‐Jensen Jakob , Nørregaard Rikke , Prætorius Helle , Nejsum Lene N. 
Published: January 2022

AbstractAimAquaporin‐2 (AQP2) shuttling between intracellular vesicles and the apical plasma membrane is pivotal in arginine vasopressin‐mediated urine concentration and is dysregulated in multiple diseases associated with water balance disorders. Children and adults with acute pyelonephritis have a urinary concentration defect and studies in children revealed increased AQP2 excretion in the urine. This study aimed to analyse AQP2 trafficking in response to acute pyelonephritis.MethodsImmunofluorescence analysis was used to evaluate subcellular localization of AQP2 and AQP2‐S256A (mimicking non‐phosphorylated AQP2 on serine 256) in cells stimulated with bacterial lysates and of AQP2 and pS256‐AQP2 in a mouse model at day 5 of acute pyelonephritis. Western blotting was used to evaluate AQP2 levels and AQP2 phosphorylation on S256 upon incubation with bacterial lysates. Time‐lapse imaging was used to measure intracellular cAMP levels in response to incubation with bacterial lysates.ResultsIn cell cultures, lysates from both uropathogenic and nonpathogenic bacteria‐mediated AQP2 plasma membrane targeting and increased AQP2 phosphorylation on serine 256 (pS256) without increasing cAMP levels. Both bacterial lysates induced plasma membrane targeting of AQP2‐S256A. Immunofluorescence analysis of renal sections from mice after 5 days of acute pyelonephritis revealed apical plasma membrane targeting of AQP2 and pS256‐AQP2 in inner medullary collecting ducts.ConclusionUropathogenic bacteria induce AQP2 plasma membrane targeting in vitro and in vivo. cAMP levels were not elevated by the bacterial lysates and AQP2 plasma membrane targeting could occur without S256 phosphorylation. This may explain increased AQP2 excretion in the urine during acute pyelonephritis.
Quantifying the relative contributions of Miocene rivers to the deep Gulf of Mexico using detrital zircon geochronology: Implications for the evolution of Gulf Basin circulation and regional drainage
Authors: Xu Jie , Snedden John W. , Fulthorpe Craig S. , Stockli Daniel F. , Galloway William E. , Sickmann Zachary T. 
Published: January 2022

AbstractSediment routing from hinterland to the deep sea is complicated because it involves evolution of river drainage from source areas to coastal plains and sediment mixing on the shelf and slope by marine currents. Previous regional paleogeographic mapping in the Gulf of Mexico (GOM) has observed a >150 km offset between the middle Miocene paleo‐Tennessee fluvial axis and the associated deep‐sea fan depositional axis, indicating a complicated sediment pathway. We integrate new and published detrital zircon (DZ) U‐Pb age data from fluvial, shelf and deep‐sea deposits to examine the complex Miocene sediment routing system in the northern GOM. These data suggest an increase in sediment load derived from western North America (increased Western Cordillera terranes; <300 Ma zircon age component) from the early to middle Miocene in the deep‐water Green Canyon protraction area. The early Miocene Green Canyon area received sediments mainly from fluvial axes located directly updip: the paleo‐Mississippi River (44%–56%; characterized by Yavapai‐Mazatzal, Mid‐Continent and Western Cordillera sourced 1800–1600 Ma, 1500–1300 Ma and <300 Ma, respectively, and Grenville‐Appalachian sourced 1300–950 Ma and 500–300 Ma age components) and smaller rivers and tributaries draining the Appalachian Mountains (e.g. paleo‐Tennessee River, 18%–43%; mainly Grenville‐Appalachian sourced 1300–9500 Ma and 500–300 Ma age components). In contrast, the middle Miocene Green Canyon deep‐sea fan shows a strong DZ signal from the paleo‐Red River (38%; increased <300 Ma zircon age component), which requires input of additional sediment sources from west of the paleo‐Mississippi system. In addition, the paleo‐Tennessee River, which was a major middle‐Miocene sediment source for the central‐eastern GOM due to uplift and increased erosion of the Appalachian Mountains, is underrepresented (34%; decreased 1300–950 Ma zircon age component) in the middle Miocene Green Canyon fan. We suggest that two mechanisms combined to produce the increased middle Miocene input from western sediment sources and restriction of locally up‐dip Tennessee River sources: (1) regional drainage changes involving middle Miocene capture of the paleo‐Red River and its tributaries by the paleo‐Mississippi River, which at the same time lost some of its eastern tributaries owing to expansion of the paleo‐Tennessee and (2) eastward (clockwise) marine transport of western‐sourced sediment along the shelf or slope, which deflected the paleo‐Tennessee signal >150 km eastward to feed the deep‐sea fan further east, perhaps reflecting intensification of a precursor to the GOM Loop Current.
The impact of an additional year in high school on academic performance at university: Evidence from a policy experiment in Ghana
Authors: Abekah‐Nkrumah Gordon , Asuming Patrick Opoku , Yusif Hadrat 
Published: January 2022

SummaryMotivationWhile education plays a fundamental role in economic development, the design of an appropriate educational structure, including duration of study at various levels, remains an issue of major policy debate in many low‐income countries. In Ghana, the issue of the length of high school education is an issue of ongoing policy debate.PurposeThis study estimates the effects of an additional year in senior high school (SHS) on academic performance at university level.Methods and approachUsing data from the two largest public universities in Ghana, the article exploits a unique natural experimental variation in the years of secondary education created by policy changes in pre‐university education in Ghana to estimate the impact of an additional year in SHS on a number of academic outcomes at university level.FindingsWe find that an additional year of SHS education has no impact on academic performance. We did not find any statistically significant difference in the likelihood of completing undergraduate studies in four years, or of graduating with a first‐class degree, or the final grade point average (GPA) of students who attended SHS for four years versus their counterparts who attended SHS for only three years. However, our descriptive analyses show that an additional year in SHS improves chances of students from less‐endowed SHS gaining admission to university, especially to health sciences programmes.Policy implicationsThe nuanced nature of the results suggests the need to further interrogate the policy on SHS duration in Ghana. This may help ensure that the implementation of the policy does not end up making some segment of the student population worse off.
Reform of higher education governance structures in Poland
Authors: Waligóra Anna , Górski Marcin 
Published: January 2022

AbstractThe implementation of a new higher education policy started in Poland in 2020. The new policy seeks to internationalise and transform universities to increase their competitiveness. This article describes the historical context, issues and reasoning behind the reform as well as some of the challenges for the future development of higher education governance structures in Poland. Current efforts to implement the new policy at leading universities in Poland are described as examples of the changing higher education governance landscape in Poland. Despite an ideological shift and change of the political system in 1989 in Poland, higher education governance has been slow to change. Polish scientists have called for higher education reforms to address a host of problems: a mismatch of the structure of the higher education system to social and economic challenges; universities suffer from limited financial autonomy; the quality of higher education is not sufficient; barriers for researchers to pursue excellence that have been identified need to be addressed. In 2016 the Polish government started a process of dialogue with the academic world in Poland, creating the foundations for the new, revolutionary bill of higher education, the Constitution for Science. The new policy of the Polish government bases, in theory, the transformation of universities on their internationalisation to make Polish science an equal partner for leading higher education centres in the world. The example of changes in Polish higher education serves a comparative reference for the development of higher education governance in Europe.
FLEXIBILITY AND PRODUCTIVITY: TOWARD THE UNDERSTANDING OF FIRM HETEROGENEITY
Authors: Macedoni Luca , Xu Mingzhi (Jimmy) 
Published: January 2022

AbstractWe document four new stylized facts using Chinese firm‐level data to show that the standard single‐attribute model of trade, in which firms only differ in productivity, must be augmented with an additional layer of heterogeneity to match the facts. To match the evidence, a model requires heterogeneity in flexibility, namely, the ability to introduce new varieties in a destination at low costs. We calibrate our model and find suggestive evidence of a trade‐off between productivity and flexibility. Furthermore, we show that ignoring firm flexibility causes a large underestimation of the welfare effects of trade.