bluuebunny/crossref_metadata_2025_split huggingface dataset:
Galectin-3 is Associated with Heart Failure Incidence: A Meta-Analysis
Authors: Baccouche Basil M. , Mahmoud Mattia A. , Nief Corrine , Patel Karan , Natterson-Horowitz Barbara 
Published: November 2022

Introduction:
Heart failure (HF) is a leading cause of death worldwide. The global
prevalence of heart failure is projected to increase rapidly in the coming decades, and significant
attention has turned to improving biomarker-based risk prediction of incident HF. This paper
aimed to qualitatively and quantitatively evaluate the evidence associating levels of galectin-3 with
the risk of incident HF.

Methods:
A review of PUBMED-indexed peer-reviewed literature was performed. Nine studies
met the inclusion criteria, and all nine had data eligible for conversion and pooling. A randomeffects
meta-analysis was performed using hazard ratios and 95% confidence intervals from a minimally
adjusted model, a further adjusted model, and from subgroups within the further-adjusted
model.

Results:
The minimally-adjusted model provided an HR of 1.97 (95% CI 1.74-2.23) when comparing
the top quartile of log-gal-3 to the bottom quartile. The further-adjusted model provided an HR
of 1.32 (95% CI 1.21-1.44) for the same comparison. The positive, significant association was conserved
during sensitivity analysis.

Conclusion:
There is a significant positive association between circulating galectin-3 and the risk
of incident heart failure. Given the complex mechanistic relationship between galectin-3 and cardiovascular
pathophysiology, further investigation is recommended for the possible implementation
of galectin-3 into clinical risk prediction models.
A Smartphone Intervention to Promote a Sustainable Healthy Diet: Protocol for a Pilot Study
Authors: Fresán Ujué , Bernard Paquito , Fabregues Sergi , Boronat Anna , Araújo-Soares Vera , König Laura M , Chevance Guillaume 
Published: November 2022

Background
Changing current dietary patterns into sustainable healthy diets (ie, healthy diets with low environmental impact and socioeconomic fairness) is urgent. So far, few eating behavior change interventions have addressed all the dimensions of sustainable healthy diets at once and used cutting-edge methods from the field of digital health behavior change.

Objective
The primary objectives of this pilot study were to assess the feasibility and effectiveness of an individual behavior change intervention toward the adoption of a more environmentally sustainable healthy diet as a whole and changes in specific relevant food groups, food waste, and obtaining food from fair sources. The secondary objectives included the identification of mechanisms of action that potentially mediate the effect of the intervention on behaviors, identification of potential spillover effects and covariations among different food outcomes, and identification of the role of socioeconomic status in behavior changes.

Methods
We will run a series of ABA n-of-1 trials over a year, with the first A phase corresponding to a 2-week baseline evaluation, the B phase to a 22-week intervention, and the second A phase to a 24-week postintervention follow-up. We plan to enroll 21 participants from low, middle, and high socioeconomic statuses, with 7 from each socioeconomic group. The intervention will involve sending text messages and providing brief individualized web-based feedback sessions based on regular app-based assessments of eating behavior. The text messages will contain brief educational messages on human health and the environmental and socioeconomic effects of dietary choices; motivational messages to encourage the adoption of sustainable healthy diets by participants, providing tips to achieve their own behavioral goals; or links to recipes. Both quantitative and qualitative data will be collected. Quantitative data (eg, on eating behaviors and motivation) will be collected through self-reported questionnaires on several weekly bursts spread through the study. Qualitative data will be collected through 3 individual semistructured interviews before the intervention period, at the end of the intervention period, and at the end of the study. Analyses will be performed at both the individual and group levels depending on the outcome and objective.

Results
The first participants were recruited in October 2022. The final results are expected by October 2023.

Conclusions
The results of this pilot study will be useful for designing future larger interventions on individual behavior change for sustainable healthy diets.

International Registered Report Identifier (IRRID)
PRR1-10.2196/41443
Understanding the Role of Support in Digital Mental Health Programs With Older Adults: Users’ Perspective and Mixed Methods Study
Authors: Borghouts Judith , Eikey Elizabeth V , De Leon Cinthia , Schueller Stephen M , Schneider Margaret , Stadnick Nicole A , Zheng Kai , Wilson Lorraine , Caro Damaris , Mukamel Dana B , Sorkin Dara H 
Published: November 2022

Background
Digital mental health interventions have the potential to increase mental health support among isolated older adults. However, the older adult population can experience several barriers to accessing and using digital health resources and may need extra support to experience its benefits.

Objective
This paper aimed to understand what older adults experience as an important aspect of support during engagement in a digital mental health program. The program entailed 3 months of staff support to participate in digital literacy training and engage with the digital mental health platform myStrength, which offers support for a range of mental health challenges, including depression and anxiety.

Methods
A total of 30 older adults participated in surveys and interviews to assess their experience of participating in a digital mental health program provided by county mental health services. As part of the program, participants attended 4 classes of digital literacy training, had access to the digital mental health platform myStrength for 2 months with staff support (and 10 months after the program without support), and received support from program staff during the entire 3-month program. Survey data were analyzed using descriptive statistics, and interview data were analyzed using thematic analysis.

Results
A thematic analysis of the interview data revealed that participants valued ongoing support in 3 main areas: technical support to assist them in using technology, guided support to remind them to use myStrength and practice skills they had learned, and social support to enable them to connect with others through the program. Furthermore, participants reported that social connections was the most important aspect of the program and that they were mainly motivated to participate in the program because it was recommended to them by trusted others such as a community partner or because they believed it could potentially help others.

Conclusions
Our findings can be used to inform the design of future digital mental health programs for older adults who may have unique support needs in terms of dedicated technical support and ongoing guided support to use technology and social support to increase social connectedness.
Teaching Genres to Advanced Learners
Authors: Tincheva Nelly 
Published: November 2022

The paper reflects recent thinking and research on what genre is, what the purposes of teaching genres are, and how genres should be taught. The paper argues a case for the application of prototype theory to teaching genres, especially with a view of teaching genres to advanced learners. To align its method with the objective specified, the paper presents perception-based data from questionnaire responses provided by a study group of 100 University students. Results from a test on both the receptive and productive skills of the respondents in the group are discussed. Final Test results of the experimental group and a control group are contrasted. The general method applied is a quantitative one as it coheres with the basic postulates of Rosch’s experimental prototype theory. The research method applied is experiment. The conclusions drawn from the study’s data corroborate strongly the applicability of the notion of prototypes to genre teaching.
Does Internationalization Promote Multilingualism? A Dutch University Study
Authors: Wilkinson Robert 
Published: November 2022

Internationalization has been a central concept in university strategic policy for several decades. Internationalization is often a key factor in both university rankings and accreditation processes. Many universities have recruited extensively students and staff globally as well as offering an international dimension within programmes. The upshot is that many university campuses are both multilingual and multicultural. However, policies to promote internationalization may lead to a context where the instructional language is English only. It is instructive to investigate how key actors perceive internationalization and its effects. Do they think it promotes monolingualism or multilingualism? This paper reports on a study into the attitudes of key staff in two faculties at a Dutch university as well as members of the central administration towards internationalization and language use. The results show that while most see internationalization as an unavoidable necessity, they subtly distance themselves from institutional policy and practice, implying a discrepancy between private and public attitudes. The internationalization policy does not stimulate multilingualism, but strengthens monolingualism. The study concludes that the educational system is missing out on the rich heteroglossic and cultural context afforded by internationalization, and suggests that a looser language policy may yield more elaborated learning outcomes.
Decolonial Gestures in Canada’s Settler State: Contemporary Indigenous Writers Jordan Abel and Leanne Simpson
Authors: Aurylaite Kristina 
Published: November 2022

This paper discusses the ways recent texts by two Indigenous Canadian writers, Jordan Abel’s collection of conceptual poetry Un/Inhabited and Leanne Simpson’s short stories and poems Islands of Decolonial Love, engage in what Walter Mignolo terms ‘decolonial gestures’ to expose the workings of contemporary settler colonialism and counter their effects. The theoretical section explains the specificities of settler colonialism that make decolonization in the sense of regaining freedom from the colonizers impossible; it then discusses the possibilities for decolonization that exist in settler countries, particularly those that refer to cultural and artistic practices. The analytical section focuses on the different strategies Abel and Simpson use in their work to enact what Mignolo calls ‘epistemic disobedience.’ Abel resorts to decolonial violence in appropriating selected texts of the genre of the Western and erasing from them to undo their loaded ideological messages. Simpson’s work, marked by explicitly confrontational rhetoric, focuses on Indigenous characters and communities, foregrounding their colonial traumas and the role of traditional knowledge and cultural practices in healing them. The paper argues that the decolonial gestures Abel and Simpson undertake work to reject the mainstream rhetoric of reconciliation, inviting Indigenous people to recognize the workings of settler colonialism and look for ways of extricating from them.
EU Presidency Programmes as a Genre
Authors: Kuzmina Jana 
Published: November 2022

Along with acting in political, economic and social arenas of the European Union, Latvia was also honoured to preside over the Council of Europe in 2015. This has resulted in the creation of the network of genres pertinent to this communicative event in both Latvian and English to reflect the discursive practices involved. In this view, the present cross-sectional empirical research aims at exploring the written genre of the European Union presidency programmes as one of fundamental documents to propose a set of tentative activities in various economically and socially significant spheres. The theoretical framework for analysis involved the fundamental principles of institutional discourse and the tenets of English for Specific Purposes and New Rhetoric Genre Schools. The exploration of the situational context involves the description of players, the discursive practices and the genre as a textual manifestation of this practice. The results of genre analysis highlight the centrality of the communicative aim and rigid generic macro-structure of a relatively novel genre, which relates to the colony of reporting genres performing the transactional language metafunction. The variation of optional moves occurs as allowed by the communicative aim, which contributes to genre integrity. The topicality of the study is determined by the scarcity of previous research on the genre in question and wide application of research findings.
Problems Students Encounter with Note-Taking in English Medium Instruction
Authors: Malavska Valerija 
Published: November 2022

The present article aimed at researching the prerequisites of success­ful note-taking by students, cognitive mechanisms involved in note-taking and the correlation of note-taking with listening skills; it describes both processes taking place while students listen to a lecture and the possible strategies that students use to take notes as well as explores the hindrances that prevent successful recording of the lecture material. It is evident that taking notes does not depend only on students’ abilities to listen and take notes, but directly depends on lecturers’ abilities and skills to deliver the information. The study carried out at Turiba University and St. Petersburg State University of Economics showed to what extent note-taking affects the process of lecture comprehension by students, whether it fosters understanding of the subject as well as to what extent note-taking of B1 – C2 English level students, according to Common European Framework of Reference for Languages (CEFR), depends on students’ abilities to take notes and on lecturers’ skills to deliver information.
Integración Óptima de Generadores Fotovoltaicos en Sistemas de Distribución DC a través de la Aplicación del Algoritmo de Optimización Aritmética Modificado
Authors: Solera Losada Nixon Andrés , Villalba Jaramillo Juan Pablo , Montoya Giraldo Oscar Danilo 
Published: November 2022

En este artículo se aborda el problema de ubicación y dimensionamiento óptimo de generadores fotovoltaicos (PV) en redes de corriente continua (CC) con el objetivo de minimizar los costos de inversión y operación de la red para la empresa de distribución de energía en un horizonte de operación de 20 años. Este problema es presentado mediante un modelo matemático de programación no lineal entera mixta (PNLEM), el cual se resuelve mediante la aplicación de una metodología de optimización del tipo maestro-esclava. La etapa maestra corresponde a una versión mejorada del algoritmo de optimización aritmética que incluye una etapa de exploración y explotación del espacio de solución que involucra la generación de nuevas soluciones a partir de la aplicación de funciones de distribución gaussiana alrededor de actual en cada iteración . En la etapa esclava se emplea el algoritmo de flujo de potencia especializado para redes de CC, el cual permite evaluar cada posible solución obtenida de la etapa maestra en relación con la ubicación (nodos) y el dimensionamiento de los generadores PV (tamaños), y verificar que todas las restricciones asociadas al modelo de PNLEM se cumplan. El resultado principal de esta investigación corresponde a una metodología mejorada basada en la combinación del algoritmo de optimización aritmética y las funciones de distribución gaussiana para mejorar las etapas de exploración y explotación del espacio de soluciones y encontrar soluciones de mejor calidad que las reportadas en la literatura especializada. En conclusión, los resultados numéricos en los sistemas de prueba IEEE 33 e IEEE 69 nodos demostraron que el algoritmo de optimización propuesto mejoró los resultados existentes en la literatura especializada para la ubicación y el dimensionamiento de fuentes PV en sistemas de distribución de CC, lo cual genera un nuevo punto de referencia para futuras investigaciones en esta temática.
Medical Costs Associated With Diabetes Complications in Medicare Beneficiaries Aged 65 Years or Older With Type 1 Diabetes
Authors: Wang Yu , Zhang Ping , Shao Hui , Andes Linda J. , Imperatore Giuseppina 
Published: November 2022

OBJECTIVE
To estimate medical costs associated with 17 diabetes complications and treatment procedures among Medicare beneficiaries aged ≥65 years with type 1 diabetes.

RESEARCH DESIGN AND METHODS
With use of the 2006–2017 100% Medicare claims database for beneficiaries enrolled in fee-for-service plans and Part D, we estimated the annual cost of 17 diabetes complications and treatment procedures. Type 1 diabetes and its complications and procedures were identified using ICD-9/ICD-10, procedure, and diagnosis-related group codes. Individuals with type 1 diabetes were followed from the year when their diabetes was initially identified in Medicare (2006–2015) until death, discontinuing plan coverage, or 31 December 2017. Fixed-effects regression was used to estimate costs in the complication occurrence year and subsequent years. The cost proportion of a complication was equal to the total cost of the complication, calculated by multiplying prevalence by the per-person cost divided by the total cost for all complications. All costs were standardized to 2017 U.S. dollars.

RESULTS
Our study included 114,879 people with type 1 diabetes with lengths of follow-up from 3 to 10 years. The costliest complications per person were kidney failure treated by transplant ($77,809 in the occurrence year and $13,556 in subsequent years), kidney failure treated by dialysis ($56,469 and $41,429), and neuropathy treated by lower-extremity amputation ($40,698 and $7,380). Sixteen percent of the total medical cost for diabetes complications was for treating congestive heart failure.

CONCLUSIONS
Costs of diabetes complications were large and varied by complications. Our results can assist in cost-effectiveness analysis of treatments and interventions for preventing or delaying diabetes complications in Medicare beneficiaries aged ≥65 years with type 1 diabetes.
Prognosis After First-Ever Myocardial Infarction in Type 1 Diabetes Is Strongly Affected by Chronic Kidney Disease
Authors: Smidtslund Patrik , Jansson Sigfrids Fanny , Ylinen Anni , Elonen Nina , Harjutsalo Valma , Groop Per-Henrik , Thorn Lena M. 
Published: November 2022

OBJECTIVE
To study prognosis after a first-ever myocardial infarction (MI) in type 1 diabetes, as well as how different MI- and diabetes-related factors affect the prognosis and risk of secondary cardiovascular events.

RESEARCH DESIGN AND METHODS
In this observational follow-up study of 4,217 individuals from the Finnish Diabetic Nephropathy (FinnDiane) Study with no prior MI or coronary revascularization, we verified 253 (6.0%) MIs from medical records or death certificates. Mortality from cardiovascular or diabetes-related cause was our main end point, whereas hospitalization due to heart failure, coronary revascularization, and recurrent MI were secondary end points, while accounting for death as a competing risk.

RESULTS
Of the individuals studied, 187 (73.9%) died during the median post-MI follow-up of 3.07 (interquartile range 0.02–8.45) years. Independent risk factors for cardiovascular and diabetes-related mortality were estimated glomerular filtration rate categories grade 3 (G3) (hazard ratio [HR] 3.27 [95% CI 1.76–6.08]), G4 (3.62 [1.69–7.73]), and G5 (4.03 [2.24–7.26]); prior coronary heart disease diagnosis (1.50 [1.03–2.20]); and older age at MI (1.03 [1.00–1.05]). Factors associated with lower mortality were acute revascularization (HR 0.35 [95% CI 0.18–0.72]) and subacute revascularization (0.39 [0.26–0.59]). In Fine and Gray competing risk analyses, kidney failure was associated with a higher risk of recurrent MI (subdistribution HR 3.27 [95% CI 2.01–5.34]), heart failure (3.76 [2.46–5.76]), and coronary revascularization (3.04 [1.89–4.90]).

CONCLUSIONS
Individuals with type 1 diabetes have a high cardiovascular and diabetes-related mortality after their first-ever MI. In particular, poor kidney function is associated with high mortality and excessive risk of secondary cardiovascular events.
Metode Pembelajaran Interaktif Penggolongan Benda pada Anak
Authors: Harefa Ester Hartati , Tegeh I Made , Ujianti Putu Rahayu 
Published: November 2022

Early age is a golden period where all aspects of the development of a child can develop rapidly and is a very potential age to train and develop various potential intelligences possessed by children. But in reality, children's cognitive abilities are decreasing this is due to the Covid-19 pandemic. By using this interactive video media, it is hoped that it can arouse students' curiosity, student interest and motivate students to learn so that it is expected to make it easier for students to understand and master the concepts of the material, as well as the information presented. The data are qualitative descriptive data analysis and quantitative descriptive data analysis. The results of the validity of the development of interactive learning videos to introduce the classification of objects for children aged 4-5 years in Paud Kasih Sifaoro'asi Village overall obtained very good qualifications. From these results, it can be concluded that the development of interactive learning videos for classifying objects for children aged 4-5 years has a very high validity so that interactive learning videos for classifying objects for children aged 4-5 years are feasible to use.

Abstrak:
Usia dini adalah periode emas untuk mengembangkan segala aspek yang anak miliki sehingga tumbuh dengan cepat dan usia ini berpotensi untuk membimbing serta melatih beragam potensi intelektual pada anak. Tetapi kenyataannya, kemampuan kognitig anak semakin menurun hal ini di sebabkan karena pandemic Covid-19. Dengan menggunakan media video interaktif ini diharapkan mampu membangun rasa keingintahuan siswa, minat sekaligus menyemangati siswa saat belajar agar siswa mampu menguasai maupun memahami konsep materi dan informasi yang disampaikan dengan mudah. Teknik analisis data penelitian ini menerapkan dua teknik analisis yaitu analisis deskriptif kualitatif dan deskriptif kuantitatif. Hasil validitas pengembangan video pembelajaran interaktif untuk mengenalkan penggolongan benda untuk anak usia 4-5 tahun di Paud Kasih Desa Sifaoro’asi secara keseluruhan mendapatkan kualifikasi sangat baik. Dari hasil tersebut, disimpulkan bahwa validitas video interaktif penggolongan benda yang dikembangkan untuk anak usia 4-5 tahun sangat tinggi maka video pembelajaran interaktif penggolongan benda layak digunakan bagi anak usia dini 4-5 tahun.