bluuebunny/crossref_metadata_2025_split huggingface dataset:
DUTIES TO ONESELF AND THIRD-PARTY BLAME
Authors: Kanygina Yuliya 
Published: February 2022

Abstract
A number of viable ethical theories allow for the possibility of duties to oneself. If such duties exist, then, at least sometimes, by treating ourselves badly, we wrong ourselves and could rightly be held responsible, by ourselves and by non-affected third parties, for doing so. Yet, while we blame those who wrong others, we do not tend to, nor do we think ourselves entitled to blame people who treat themselves badly. If we try, they might justifiably respond that it is none of our business. This disanalogy might be thought of as a reason for skepticism about duties to oneself. It allegedly indicates that self-inflicted harm, while irrational, is not immoral. In this paper, I argue that this disanalogy is deceptive. First, it relies on the unjustified assumption that our response to someone treating herself badly consists solely in a judgment that she is being irrational or foolish, which is incompatible with leading views about what constitutes blame. Second, the objection fails to recognize that third-party blame is positional: in some contexts, it is inappropriate for a third party to express blame just because of her position as a third party.
PROPORTIONAL REPRESENTATION OF WOMEN IN ELITE ETHICS JOURNALS: TO QUOTA OR NOT TO QUOTA?
Authors: Krishnamurthy Meena 
Published: February 2022

Abstract
In this paper, I paper explore one concrete manifestation of the gender problem in philosophy: namely, the underrepresentation of women in elite ethics journals. After presenting existing data regarding the underrepresentation of women-authored papers in elite ethics journals, I give some reasons for favoring proportional representation. I conclude by discussing gender-based quotas as one potential avenue of ensuring proportional representation of women in elite ethics journals. I canvass the usual and obvious reasons that are given for immediately dismissing quotas and argue that these reasons do not hold. This suggests, at minimum, that gender-based quotas should not be outright dismissed as a potential (albeit partial) solution to the gender problem in philosophy and that quotas are deserving of more consideration.
WHY SO FEW WOMEN IN VALUE JOURNALS? HOW COULD WE FIND OUT?
Authors: Saul Jennifer 
Published: February 2022

Abstract
This paper takes as its starting place Meena Krishnamurthy’s discussion in this issue of women’s underrepresentation in "elite" value journals. Her paper discusses a specific remedy: quotas. My paper focuses instead on the causal issue of explanations for women’s underrepresentation in these journals. I argue that we currently lack the data that would allow us to choose between various hypotheses (or combinations of hypotheses), and I sketch the sorts of investigations that would be needed to further our understanding of the causes for this underrepresentation.
WHO NEEDS CONSENSUS ANYWAY? ADDRESSING MANUFACTURED DOUBT AND INCREASING PUBLIC TRUST IN CLIMATE SCIENCE
Authors: Intemann Kristen 
Published: February 2022

Abstract
Several empirical studies purportedly demonstrate the existence of a scientific consensus on climate change. Such studies have been pursued as a response to concerns that private industries and think tanks have "manufactured" public doubt and derailed regulatory policies. While there is overwhelming evidence for anthropogenic global warming, studies aiming to empirically establish the existence of consensus rely on several problematic assumptions about the nature of consensus and the role of consensus in policy making. Even more worrisome, reinforcing such assumptions in public may actually undermine, rather than increase, trust in climate science.
SCIENTIFIC DISSENT AND A FAIR DISTRIBUTION OF EPISTEMIC RESPONSIBILITY
Authors: Rolin Kristina 
Published: February 2022

Abstract
There is a growing concern about the epistemic harms that may be caused by what appears to be politically and economically motivated dissent within scientific communities. Acknowledging the urgency to develop criteria for normatively appropriate dissent in science, many philosophers have turned to Helen Longino’s account of epistemically ideal communities suggesting that dissenters as well as consensus scientists ought to follow the four criteria of publicly recognized scientific venues, uptake of criticism, shared standards, and tempered equality of intellectual authority. I argue that Longino’s account is in need of refinement. In order to minimize the epistemic harms that may be caused by scientific dissent, the criterion of uptake needs to include a requirement for a fair distribution of epistemic responsibility.
INTRODUCTION: THE RESPONSIBLE USE OF SCIENCE IN SOCIETAL DECISION MAKING—PART 2
Authors: Elliott Kevin C. , Richards Ted 
Published: February 2022

Abstract
Science plays a crucial role in a great deal of personal and societal decision making, including the development of public policy and regulations, the formulation of legal decisions, and the preservation of public and environmental health. Nevertheless, recent scholarship has shown that the incorporation of science into public decision making is fraught with a great deal of complexity. This essay introduces the second of two special sections of Public Affairs Quarterly, which together comprise six articles that explore cutting-edge questions about how science can be used responsibly to inform societal decisions. The articles in this second section explore how to develop regulatory and legal institutions that treat science with appropriate respect without granting inappropriate decision-making power to the scientific community.
Unindo as peças de um quebra-cabeça: perspectivas dialéticas e a gênese documental na formação inicial de professores de Matemática
Authors: F.C de Assis Cibelle , Trouche Luc 
Published: February 2022

Este artigo tem como objetivo ilustrar a Gênese Documental considerando uma situação real de planejamento e implementação de uma aula vivenciada por uma estudante de licenciatura em Matemática na perspectiva das três dialéticas instrumentação/instrumentalização, recurso “mãe”/recurso “filho” e atividade produtiva/ atividade construtiva. A situação real a que nos referimos compôs um dos estudos analisados durante o estágio pós-doutoral da primeira autora na UFPE e na ENS/Ifé de Lyon, entre os anos de 2016 e 2018. Para a releitura dos dados, elencamos três questões norteadoras: no que a estudante se apoia em termos de recursos? Quais as razões das suas escolhas? Quais são as aprendizagens no processo formativo? Como referencial teórico e metodológico, nós apoiamos na Abordagem Documental do Didático. Na análise da dialética instrumentação e instrumentalização, tivemos respostas para as perguntas: no que a estudante se apoia em termos de recursos? Quais são as adaptações? e observamos os recursos utilizados a partir do documento tarefa. Também neste estudo identificamos os recursos “mãe” e "filho”. No estudo dessas duas dialéticas inferimos o nascimento de um sistema de recursos da estudante construído para ensinar classificação de triângulos com o Geogebra. Na dialética atividade produtiva/atividade construtiva, tivemos respostas para as perguntas: quais as razões das suas escolhas? e quais foram as aprendizagens no processo formativo? quando analisamos os invariantes operatórios do esquema de criação de uma tarefa. O estudo das versões da tarefa foi essencial para identificarmos conhecimentos, crenças e aprendizagens da futura professora.
Los sistemas de alerta temprana, una herramienta que fortalece la vigilancia epidemiológica en el marco de la seguridad y salud en el trabajo
Authors: Rizo-Tello Victor Zein , Aguilera-Becerra Astrid Maribel , Ramírez-López Laura Ximena 
Published: February 2022

Introducción: Las enfermedades y los accidentes laborales no solo reducen la productividad y la capacidad de trabajo, sino que también generan altos costos para los trabajadores, empresas, familias, el sistema de salud y la sociedad, motivo por el cual en los últimos años se han convertido en un problema de salud pública que preocupa a las empresas y al gobierno, porque se requiere un enfoque preventivo y anticipado integral. Objetivo: compilar información actualizada y relevante acerca de los sistemas de alerta temprana que puedan aplicarse en el marco de la vigilancia epidemiológica en la seguridad y salud en el trabajo. Materiales y métodos: Revisión narrativa de la literatura, a partir de la búsqueda en diferentes bases de datos de artículos publicados durante 2016-2021. Los documentos seleccionados fueron artículos originales, de revisión, guías de manejo, implementación y legislación nacional, que abordan los temas de inteligencia epidemiológica, sistemas de alerta temprana y seguridad y salud ocupacional. Resultados: Los sistemas de alerta temprana son herramientas que permiten proveer una información oportuna y eficaz que ayuda a los individuos expuestos a tomar decisiones para evitar o reducir el riesgo. Conclusiones: La implementación de un sistema de alerta temprana en las empresas ayudará a disminuir los tiempos desde la identificación del riesgo hasta la respuesta y, así, con una mayor oportunidad de control, se influirá en la salud de los trabadores, la producción y finanzas de la empresa.
Hyperoxaluria: An early diagnosis will allow a timely combined renal and liver transplantations to avoid irreversible damages to all other organs
Authors: Kottos Elisa , Adams Brigitte , Biarent Dominique , Beretta-Piccoli Xavier , Ismaili Khalid , De Bels David , Honore Patrick M. , Redant Sebastien 
Published: February 2022

ABSTRACT
A 4-month-old patient was admitted to the emergency room for vomiting, weight gain, food refusal and hypertension. Blood gases showed a metabolic acidosis with increased anion gap. Laboratory finding revealed severe renal failure (creatinine 8 mg/dL). Renal ultrasound showed an important hyperechogenicity of the parenchyma with loss of cortico-medullar differentiation suggesting a nephronophytosis. Genetic testing was negative. Urine oxalate levels were increased to 140 μmol/L. New genetic tests were positive for type I hyperoxaluria. The authors discuss the management of hyperoxaluria.
The challenges and optimization of cell-based therapy for cardiovascular disease
Authors: Xu Shiyue , Qiu Yumin , Tao Jun 
Published: February 2022

ABSTRACT
With the hope of achieving real cardiovascular repair, cell-based therapy raised as a promising strategy for the treatment of cardiovascular disease (CVD) in the past two decades. Various types of cells have been studied for their reparative potential for CVD in the ensuing years. Despite the exciting results from animal experiments, the outcome of clinical trials is unsatisfactory and the development of cell-based therapy for CVD has hit a plateau nowadays. Thus, it is important to summarize the obstacles we are facing in this field in order to explore possible solutions for optimizing cell-based therapy and achieving real clinical application.
Lipid-related protein NECTIN2 is an important marker in the progression of carotid atherosclerosis: An intersection of clinical and basic studies
Authors: Li Shen , Gao Yuan , Ma Ke , Li Yanan , liu Chen , Yan Yingxue , Liu Weishi , Liu Hongbing , Li Zhen , Song Bo , Xu Yuming , Xia Zongping 
Published: February 2022

ABSTRACT

Background:
The nectin cell adhesion molecule 2 (NECTIN2) protein is a cell adhesion molecule involved in lipid metabolism. We aimed to explore the potential role of NECTIN2 in carotid atherosclerosis (CA).

Materials and Methods:
Patients who underwent carotid endarterectomy (CEA) at the First Affiliated Hospital of Zhengzhou University were enrolled in this study. APOE-/- rats fed western or normal diet were used to model early pathological changes in CA. The relationship between patients’ lipid indices and plaque severity was assessed using ordinal regression analysis. Mendelian randomisation (MR) analysis was used to determine the causal links between low-density lipoprotein cholesterol (LDL-C) and atherosclerosis. After matching analysis of the single-cell transcriptome and microarray data of carotid plaques, NECTIN2 was identified as a key factor affecting CA. The importance of NECTIN2 was further verified by immunofluorescence staining of CEA and APOE-/- rat specimens.

Results:
A total of 108 patients were included. The traditional lipid indices did not correlate significantly with the plaque severity (P > 0.05). NECTIN2 provided a strong causal link between LDL-C level and CA (MR effect size >0). Deep-sequencing data illustrated that NECTIN2 expression was cell specific. In early-stage CA, NECTIN2 expression was increased in endothelial cells; however, in advanced-stage CA, NECTIN2 was overexpressed in macrophages located in fibrous caps. APOE-/- rat carotid artery and human carotid plaques modelled the entire atherosclerotic process, showing an upregulation of NECTIN2 expression in CA.

Conclusions:
Lipid-related protein NECTIN2 is a potential marker in CA progression and can potentially be a new therapeutic target for clinical prevention.
Convergence and Stability of Iterative Scheme for a Monotone Total Asymptotically Non-expansive Mapping
Authors: Abed SalwaSalwa Salman , Abed Athraa Najeb 
Published: February 2022

In this work, we introduce Fibonacci– Halpern iterative scheme ( FH scheme) in partial ordered Banach space (POB space) for monotone total asymptotically non-expansive mapping (, MTAN mapping) that defined on weakly compact convex subset. We also discuss the results of weak and strong convergence for this scheme.
Throughout this work, compactness condition of m-th iterate of the mapping for some natural m is necessary to ensure strong convergence, while Opial's condition has been employed to show weak convergence. Stability of FH scheme is also studied. A numerical comparison is provided by an example to show that FH scheme is faster than Mann and Halpern iterative schemes.
Faktor Risiko Kejadian Green Tobacco Sickness (GTS) pada Buruh Tani Tembakau: Literature Review
Authors: Rizki Audini Fathia , Wahyuningsih Nur Endah , Budiyono Budiyono 
Published: February 2022

Abstract
Background: Background: Green Tobacco Sickness (GTS) is a form of nicotine poisoning caused by direct contact between the skin of tobacco farm workers and wet tobacco plants during the planting and harvesting process. This study aims to analyze the risk factors for the incidence of GTS in tobacco farmers. Method: The method used was a literature review. Articles were obtained from the online database Scopus, PubMed, ProQuest, Google Scholar, and Garuda Portal published during 2010-2020. The selected article used an observational study design and discussed the risk factors for the incidence of GTS in tobacco farmers. The assessment of the quality of the articles used guidelines from the Joanna Briggs Institute. Based on the article search, twelve articles were consisting of three articles from national journals and nine articles from international journals. Article analysis was carried out by comparing the percentage of significant variables in the entire article. This study resulted in the most dominant risk factor for GTS is the use of personal protective equipment with a percentage of 50% of the total articles.
Hubungan antara Ukuran Massa dan Derajat Tumor dengan Glasgow Coma Scale Pra dan Pasca Tumor Reseksi Bedah Meningioma dan Karnorfsky Performance Scale Pasca Tumor Reseksi Bedah Meningioma di RSUD Abdul Wahab Sjahranie Samarinda Januari 2018 – Maret 2020
Authors: Ishaq Berta Ramadhani , Ibrahim Arie , Iskandar Abdillah 
Published: February 2022

Meningioma merupakan tumor primer intrakranial yang umum dijumpai, yaitu sekitar 37% dari seluruh tumor sistem saraf pusat, meningioma juga merupakan tumor jinak ekstraaksial atau tumor yang terjadi diluar jaringan parenkim otak dan mengalami peningkatan angka kejadian pada populasi usia tua. Sekitar 20% dari meningioma bersifat jinak dan 4% dapat mengalami kekambuhan walaupun telah direseksi total. Tumor ini masih butuh banyak penelitian lebih lanjut yang dikarenakan masih membutuhkan bukti jelas mengenai tumor ini mulai dari etiologi hingga pemulihan. Penelitian ini merupakan penelitian analitik dengan pendekatan cross-sectional yang bertujuan untuk mengetahui mengetahui hubungan antara ukuran massa, lokasi, dan derajat tumor dengan Glasgow Coma Scale (GCS) pra dan pasca tumor reseksi bedah Meningioma dan Karnorfsky Performance Scale (KPS) pasca tumor reseksi bedah Meningioma. Sumber data pada penelitian ini adalah data sekunder yang diperoleh dari ruang rekam medik RSUD Abdul Wahab Sjahranie Samarinda. Sampel dalam penelitian ini adalah semua pasien yang didiagnosis Meningioma dan telah menjalani Reseksi Bedah Saraf di RSUD Abdul Wahab Sjahranie Samarinda dalam periode Januari 2018 – Maret 2020 yang memenuhi kriteria inklusi dan kriteria eksklusi. Penentuan besar sampel menggunakan teknik total sampling, dan pengambilan sampel dilakukan secara purposive sampling sehingga didapatkan 31 pasien dalam penelitian ini. Hasil yang didapatkan terdapat adanya hubungan antara ukuran massa tumor dengan GCS pra maupun pasca reseksi bedah Meningioma, terdapat hubungan antara ukuran massa dan derajat tumor dengan KPS pasca reseksi bedah Meningioma, terdapat hubungan antara derajat tumor dengan GCS pra reseksi bedah Meningioma, dan terdapat hubungan antara derajat tumor dengan GCS pasca reseksi bedah Meningioma. Tidak terdapat adanya perbedaan antara GCS pra dengan pasca reseksi bedah namun terdapat adanya hubungan dalam hasil tersebut.
Kata Kunci : Meningioma, Ukuran Massa Tumor, Derajat Tumor, GCS, KPS
Potensi Medication error Pada Resep di Salah Satu Apotek di Kota Kadipaten
Authors: Lisni Ida , Gumilang Nurani Eka , Kusumahati Eva 
Published: February 2022

Medication errors can occur in each process, at prescribing, transcribing, dispensing, and administration processes. This study is to find out that the prescribing stages have met the legality principle by the RI Minister of Health Regulation Number 73 of 2016 and continued with the determination of the Medication Error Index (NCC MERP). This research method is non-experimental observational. The research was conducted by collecting prescriptions for the period July - December 2019 retrospectively. The sample size in the study was determined by a systematic random sampling technique based on the Slovin formula. 1,581 prescriptions were obtained and the results of the samples taken were 352 prescriptions. The results showed that there were prescriptions that did not meet the administrative requirements were 17.9%, did not meet the pharmaceutical requirements of 44.9%, and those that did not meet the clinical requirements were 7.5%. The results of the analysis of the characteristics of the Medication Error Index for category C were 68%, category D was 0.5%, and category E was 1.8%.
Keywords : Pharmacy; Prescription; Medication Error
Gambaran Gejala Depresi pada Mahasiswa Fakultas Kedokteran Universitas Mulawarman
Authors: Faizah Nilna Nur , Sulistiawati Sulistiawati , Nugrahayu Eka Yuni , Mualimin Jaya , Ibrahim Arie 
Published: February 2022

Abstract
The prevalence of depressive symptoms among medical students is known to be higher because they have been faced with variety of stressors. The purpose of this study was to determine the depressive symptoms among undergraduate medical students of Mulawarman University. This was a quantitative descriptive research with univariate analysis. Beck Depression Inventory (BDI) was used to collect the primary data. A cross-sectional study was conducted on a total of 364 sampled students selected by purposive sampling technique. The obtained data were described using descriptive statistics. The results of this study showed that 177 students (48,6%) had low (minimal) levels of depression, 93 students (25,6%) had mild depression, 62 students (17,0%) had moderate depression, and 32 students (8,8%) had severe depression. In summary, most students in the Medical Study Program of Mulawarman University had minimal depressive symptoms.
Abstrak
Prevalensi gejala depresi pada mahasiswa kedokteran diketahui lebih tinggi karena mereka dihadapkan dengan stresor yang bervariasi. Tujuan penelitian ini yaitu untuk mengetahui gejala depresi pada mahasiswa kedokteran preklinik di Universitas Mulawarman. Penelitian ini merupakan penelitian deskriptif kuantitatif dengan analisis univariat. Beck Depression Inventory (BDI) digunakan untuk mengumpulkan data primer. Studi potong lintang dilakukan pada 364 mahasiswa menggunakan teknik purposive sampling. Data yang telah diperoleh dideskripsikan menggunakan statistik deskriptif. Hasil penelitian menunjukkan sebanyak 177 (48,6%) mahasiswa memiliki tingkat depresi rendah (minimal), 93 mahasiswa (25,6%) memiliki gejala depresi ringan, 62 mahasiswa (17,0%) memiliki gejala depresi sedang, dan 32 mahasiswa (8,8%) memiliki gejala depresi berat. Sebagai kesimpulan, sebagian besar mahasiswa kedokteran Universitas Mulawarman memiliki gejala depresi minimal.
Hubungan Usia dengan Stadium Saat Diagnosis Penderita Kanker Kolorektal di RSUD Abdul Wahab Sjahranie Samarinda
Authors: Zannah Sri Jatul , Murti Ignatia Sinta , Sulistiawati Sulistiawati 
Published: February 2022

Abstract
Background: Colorectal cancer is a malignancy originating from the colon tissue. The incidence of colorectal cancer was recorded at 396,914 new cases with 234,511 deaths and the fourth rank of all types of cancer cases in Indonesia. This study aims to determine the relationship between age and histopathological features and stage when diagnosed with colorectal cancer at Abdul Wahab Sjahranie Hospital, Samarinda. Methods: The study design was retrospective analytic with a cross sectional study approach. The research data came from the medical records of colorectal cancer patients at Abdul Wahab Sjahranie Hospital, Samarinda in 2017-2020. Results: A total sample size of 71 samples. Data analysis statistically showed the relationship between age and stage at diagnosis with p = 0.004 (p = 0.05). Conclusion: The relationship between age and stage at diagnosis of colorectal cancer patients at Abdul Wahab Sjahranie Hospital, Samarinda.
Keywords: Colorectal Cancer, Age, Stage