bluuebunny/crossref_metadata_2025_split huggingface dataset:
Idealization of rough sets and medical applications in decision-making the impact factors of COVID-19 infections and heart attacks
Authors: Hosny Mona 
Published: February 2022

Abstract
Rough set theory is a mathematical technique to address the issues of uncertainty and vagueness in knowledge. It relies mainly on two approximations namely, lower and upper approximations which are used to study the boundary region and accuracy measure. Ideal is considered as a crucial research of extension this theory. As, it is efficacious tool to dispose of vagueness and uncertainties by helping us to approximate the rough set in a more general manner, accurate and increase the accuracy measure. Minimizing the boundary region is one of the pivotal and substantial themes for studying the rough sets which consequently aims to maximize the accuracy measure. Ideal is one of the effective and successful followed methods to achieve this goal perfectly. So, the object through this work is to present new methods in rough set via ideals. Moreover, these methods are also based on the maximal right neighborhood generated by binary relations not similarity relations as in the previous studies. Accordingly, the present techniques are extended the applications fields of the rough sets. As, the similarity relations do not always hold in many real-life applications and consequently this restriction limits the wide applications of this set as it is shown in the end of this paper. Some important characteristics of these methods are scrutinized and demonstrated that they are generated accuracy measures greater and higher than the former ones in the other approaches. Afterwards, it is elucidated that the corresponding upper and lower approximations, boundary regions, accuracy measures and roughness measures are monotonic. Finally, two medical applications are introduced to show the significance of utilizing the ideals in the proposed methods and how it plays an intrinsical and a substantial role in the decision making problems. It enables us to decide the impact factors of COVID-19 infections and heart attacks. As, it handles any imperfect data in symptoms of the diseases and this automatically makes the diagnosis of patients easily and perfectly. Consequently, this help the medical staff to make a precise decision about the diagnosis of patients
A comparative investigation of using microbial- and CO2-induced carbonate minerals in sustainable soil Improvement
Authors: Zangani Alireza , keykha hamed Abdeh , Romiani Hadi Mohamadzadeh , Asadi Afshin , Kawasaki Satoru , Radmanesh Niloofar 
Published: February 2022

Abstract
The structure and shape of carbonate crystals formed by microbial activity and carbon dioxide reaction were investigated in this work. The mineral carbonates treated sandy soil was subsequently determined using unconfined compression tests (UCS). Sporoscarcina pasteurii bacteria were used to produce an aqueous solution of free carbonate ions (CO32-) under laboratory circumstances called microbial-induced carbonate precipitation (MICP). In CO2- induced carbonate precipitation, carbon dioxide was added to a sodium hydroxide solution to form free carbonate ions (CO32-) (CICP). Different carbonate mineral compositions were then provided by adding Fe2+, Mg2+, and Ca2+ ions to carbonate ions (CO32-). In the MICP and CICP procedures, the results of scanning electron microscopy (SEM) and X-ray powder diffraction (XRD) revealed a distinct morphology of carbonate minerals. Vaterite (CaCO3), siderite (FeCO3), magnesium carbonate hydrate, or Nesquehonite (MgCO3 (H2O) 3) and dolomite (CaMg(CO3)2) were produced in MICP. Calcite (CaCO3), siderite (FeCO3), magnesium carbonate hydrate or Nesquehonite (MgCO3 (H2O) 3), and high-Mg calcite (CaMg(CO3)2) were produced in CICP. The results of UCS showed that siderite and high-Mg calcite /dolomite had more efficiency in soil strength. The lowest value of strength was related to magnesium carbonate hydrate treated soils. Mineral-treated soils in CICP showed a slightly higher UCS strength than MICP, which could be attributable to greater crystal particle sizes and particle interlocking.
A Survey of Multidisciplinary Healthcare Providers Utilizing The Knowintegrativeoncology.Org Educational Platform
Authors: Green Jen , Wright Heather , Seely Dugald , Legacy Mark , Anderson Maureen , Armstrong Hallie , Martell Casey , Soles Sarah , Balneaves Lynda G. 
Published: February 2022

Abstract
Background: Although the vast majority of cancer patients use natural health products (NHPs), 59% of oncology healthcare providers (HCP) report not receiving any education on NHPs. KNOWintegrativeoncology.org (KNOW) is a web-based educational platform that provides up-to-date evidence on NHPs used in cancer care with a user-friendly interface. KNOW is a database of human studies systematically gathered from MEDLINE and EMBASE. We surveyed HCPs before and after accessing KNOW to identify their information needs regarding NHPs in cancer care, their preferred way to receive information, barriers they face accessing NHP information, and to obtain feedback on the website. Methods: Recruitment was done through Beaumont Health Systems, the Society for Integrative Oncology, and the Andrew Weil Centre for Integrative Medicine, University of Arizona. HCPs who consented completed an initial survey and then a follow-up survey after being given access to KNOW for 4-6 weeks. Participants were required to access KNOW at least three times before completion of the follow-up survey. Results: A total of 65 participants completed the initial survey, with 60% (n=39) from the conventional medical community, 33% (n=21) from the integrative medicine community, and 7% (n=5) from the research community. The majority of participants (82%; n=53) preferred educational websites to email updates, podcasts/webinars, in-house experts, PubMed searches and smartphone apps. The most common barriers identified to accessing information on NHPs were time, accessibility at point-of-care, and credibility of sources. A high number of participants were lost to follow up, with 18 participants demographically representative of the initial sample of 65 completing the follow-up survey. Half (n=9) of participants stated accessing the KNOW website changed their clinical practice. Close to 90% (n=16) reported they would recommend KNOW to a colleague. Conclusion: The majority of oncology HCPs prefer to use, and already rely on, numerous web-based educational platforms to gather information on NHPs, with time, accessibility, and credibility being common barriers to obtaining information. Our study results indicate that KNOW helped reduce some of these barriers and HCPs were highly satisfied with the resource. KNOW is a comprehensive, easy-to-use web-based educational resource to access up-to-date research on NHPs in cancer care.
Barriers and facilitators of nutrient intake efficiency in Iran(a new perspective on food waste management)
Authors: Pakravan Mohammad Reza , Flora Cornelia 
Published: February 2022

Abstract
BackgroundPaying particular attention to sustainable food consumption in low-income households is essential ‎for reducing food waste. Due to the growing population globally, this concept will likely become more ‎serious soon. MethodsFollowing the importance of optimizing food consumption for ‎sustainability, in this study, a novel methodology is introduced for calculating nutrient intake ‎efficiency and determining the kind of choosing food to minimize food waste in ‎different locations. Also, the impact of socio-economic factors on nutrition efficiency was assessed. ‎Data Envelopment Analysis (DEA) and a Tobit model are used to achieve the goals. Household ‎Consumption and Expenditure Surveys (HCES) of 30,000 rural and urban Iranian households were ‎used in all provinces in 2016. Finally, the Nutrient Efficiency Map (NEM) of Iran was depicted by GIS ‎software. ResultsThe results showed that many townships had nutrient efficiency scores of less than 70%. ‎Northeast townships had the lowest scores, with an efficiency score of less than 50%. ‎Overall, townships have lower efficiency in the North (seaside cities), East (desert cities), and North ‎East (isolated cities) compared with other areas.Conclusions Therefore, it is suggestible that the government ‎should modify the support policies and the protection packages based on social, geographical ‎, and cultural status.
Planning and Developing a Web-Based Intervention for Active Surveillance in Prostate Cancer; An Integrated Self-Care Programme for Managing Psychological Distress
Authors: Hughes Stephanie , Kassianos Angelos P. , Everitt Hazel , Stuart Beth , Band Rebecca 
Published: February 2022

Abstract
Objectives:To outline the planning, development and optimisation of a psycho-educational behavioural intervention for patients on active surveillance for prostate cancer. The intervention aimed to support men manage active surveillance related psychological distress.Methods:The person-based approach (PBA) was used as the overarching guiding methodological framework for intervention development. Evidence-based methods were incorporated to improve robustness. The process comprised of the following four components:· A systematic review and meta-analysis of depression and anxiety in prostate cancer· A cross-sectional survey on depression and anxiety in active surveillance· A review of existing interventions in the field· A qualitative study with the target audienceThe purpose of this paper is to bring these components together and describe how they facilitated the establishment of key guiding principles and a logic model, which underpinned the first draft of the intervention.Results:The prototype intervention, named PROACTIVE, consists of six internet-based sessions run concurrently with three group support sessions. The sessions cover the following topics: lifestyle (diet and exercise), relaxation and resilience techniques, talking to friends and family, thoughts and feelings, daily life (money and work), and includes information about prostate cancer and active surveillance.Conclusions:The planning and development process is key to successful delivery of an appropriate, accessible and acceptable intervention. The PBA strengthened the intervention by drawing on target-user experiences to maximise acceptability and user engagement. This meticulous description in a clinical setting using this rigorous but flexible method is a useful demonstration for others developing similar interventions.Trial registration and ethical approval:NRES Committee South Central – Oxford A. REC reference: 11/SC/0355IRAS project ID: 83650
The Cutoff Value and Prognosis of Anti-PLA2R for Idiopathic Membranous Nephropathy: A Single- Center Retrospective Study From China
Authors: Guo Hongxia , Yao Yao , Zhou Jiansuo , Wang Song , Wang Yue , Zheng Danxia 
Published: February 2022

Abstract
Background：Analyzing the antibody level of anti-phospholipase A2 receptor (anti-PLA2R) with idiopathic membrane nephropathy (IMN) and its correlation with clinical parameters and prognosis, and to explore optimal cut-off value for Chinese patients. Methods All hospitalized patients with renal biopsy from April 2017 to November 2019 in Peking University Third Hospital whose clinical and pathological characteristics were analyzed, and the level of serum PLA2R antibodies was detected using the method of enzyme-linked immunosorbent assay (ELISA). Result: The sensitivity, specificity, and Youden index of anti-PLA2R in the diagnosis of IMN in the Chinese patients were 85.7%, 88.3%, and 0.740 for the 2.5 RU/ml cut-off value; 77.8%, 96.0%, and 0.737 for the 6.3RU/ml cutoff value, respectively. The area under the ROC curve was 0.916. Compared with the high titer group, the low titer group had a higher serum albumin level (p=0.016), a lower cholesterol level (p=0.025) and a lower low density lipoprotein cholesterol (p=0.010). Multivariable Cox regression analysis showed that just immunosuppressive therapy (adjusted HR=4.656, 95 % CI 1.461-14.839, p=0.006) was associated with higher remission rate of IMN patients. Conclusion: The best cutoff for ELISA method to detect anti-PLA2R antibodies in IMN patients is probably much lower (around 2-7 RU/ml) than that indicated by the manufacturer. The cut-off value of 6.3 RU/ml could get a higher sensitivity and not a lower specificity. If the IMN patients were treated actively, they maybe can get better prognosis.
Diversity Analysis of Rhizosphere Soil Microbial Population Structure and Screening and Identification of Dominant Salt-Tolerant Strains of JunCao"Oasis No. 1"
Authors: Xiao ZhiQi , Lin ZhanXi 
Published: February 2022

Abstract
Purpose: As a newly cultivated grass species widely used in saline-alkali soil treatment, Juncao"Oasis No.1" can effectively enhance the microbial population abundance in saline-alkali soil. It has a good effect on improving saline-alkali soil.Methods: In order to further study the microbial community in the rhizosphere soil of Juncao"Oasis No.1" , the dominant strains with important ecological value were screened out. In this paper, soil samples were collected from saline-alkali soil planted with Juncao"Oasis No. 1" and unplanted Juncao"Oasis No. 1", and the microbial populations were sequenced by 16SrDNA high-throughput sequencing, in order to identify the difference of microbial population, the dominant bacteria in rhizosphere soil of Juncao"Oasis No. 1" was selected, and the dominant bacteria with important ecological value were isolated and cultured and identified by Colony PCR.Results: The results showed that Pseudomonas fluorescens and Bacillus thuringiensis. were the dominant strains with important ecological value in rhizosphere soil of Juncao"Oasis No.1" . After isolation and culture, Colony PCR identification showed that the dominant strain was successfully isolated and cultured.Conclusions: In this paper, the dominant strains with important ecological value in rhizosphere soil of Juncao" Oasis No. 1" were screened and cultured, which provided theoretical basis for the improvement of saline-alkali soil by using Juncao"Oasis No. 1", it is of great guiding significance.
Theoretical study of the influence of heteroatoms (N, B, Si) on the interaction of aluminum and iron clusters with a carbon graphene-like plane
Authors: Demianenko Eugeniy , Terets Mariia , Ushakova Liudmyla , Zhuravskyi Serhii , Sementsov Yurii , Lobanov Viktor , Filonenko Oksana , Kuts Volodymyr , Kartel Mykola 
Published: February 2022

Abstract
Metal composites modified with various heteroatoms, such as N, B, Si, are used to obtain matrix composites with specifie parameters with the strongest adhesion-cohesion bonds between metal atoms and carbon nanoparticles. Such functionalized heteroatoms carbon nanoparticles are promising for metal composites.The aim of the study was to determine the effect of temperature on the chemical interaction of aluminum and iron clusters with native, boron-, silicon- and nitrogen-containing graphene-like planes (GLP).The values of the energy effect of reactions (ΔEreact) of Al2 and Fe2 dimers with native and modified GLP, as well as the dependence of their free Gibbs energy on temperature are calculated. The highest positive value of the energy effect of the reaction of the native graphene-like plane was set for the aluminum dimer.The energy effect of the reactions between GLP C22B2H12 and the dimer Fe2 and is ‑210.5 kJ/mol. The energy effect of the reactions between GLP C22B2H12 and dimer Al2 is much smaller (‑2.4 kJ/mol). For the interaction of GLP C22N2H12 with dimers Al2 and Fe2, the energy effect of the reaction in the result of calculations: ‑100.4 and ‑94.6 kJ/mol, respectively.For silicon carbide cluster with dimers Al2 and Fe2, they turned out to be exothermic with energy effects of ‑25.1 and ‑136.6 kJ/mol, respectively. In addition, of all the cases considered, for the interaction of GLP C22N2H12 with Al2, the curve of the Gibbs free energy of the reaction on temperature is below the curve for the iron dimer.
Phenotypic and Start Codon Targeted (SCoT) polymorphism reveals the genetic variation of Crataegus bretschneideri C. K. Schneid. and related species in China
Authors: Zhang Xiao , Sun Xinyu , Wang Jian , Xue Miliao , Sun Chao , Dong Wenxuan 
Published: February 2022

Abstract
Crataegus bretschnesideri C. K. Schneid. originated in Northeast China, it has excellent characteristics of cold resistance and early maturity. However, the taxonomic status of C. bretschnesideri has been controversial due to the intra-specific hybridization and apomixes. Comparative assessment of phenotypic and molecular evaluations used to explore genetic diversity of C. bretschneideri and relative species. Qualitative and quantitative traits of C. bretschneideri and relative species were evaluated. Genetic diversity and population structure of several Crataegus species were analyzed by thirteen reported and five newly designed SCoT markers. Leaf traits of Crataegus had a higher Shannon-wiener index than fruit and flower traits; Fruit contained diverse traits among seven Crataegus species by principal component analysis. SCoT markers amplified 148 polymorphic bands with 94.87% polymorphic loci. Crataegus individuals clustered into five clades, and C. bretschneideri had a closer relationship with C. pinnatifida Bge. and C. hupehensis Sarg.. Population structure suggested that investigated the mixed gene pool appeared in C. bretschneideri. There had variation among Crataegus species, and part of the C. bretschneideri individuals may be a hybrid origin compared to the phenotypic and molecular evaluations. Newly designed SCoT markers were practical for Crataegus diversity analyses.
The Value of Whole-tumor CT Texture Analysis as a Quantitative Biomarker in the Identification of Solid Renal Tumors
Authors: Meng Xiaoyan , Li Shichao , Feng Cui , Hu Daoyu , li Zhen , Niu Yonghua 
Published: February 2022

Abstract
Background: Renal tumors are very common in the urinary system. Preoperative diagnosis for the renal tumor is very important for postoperative prognosis evaluation, surgical method selection, and follow-up observation. This study was to evaluate the value of the whole-tumor CT texture analysis for identification of solid renal tumors without hemorrhage, necrotic or cystic changes.Methods: 128 patients were included and successfully performed contrast-enhanced CT examinations. All cases were pathologically confirmed. The whole-tumor texture analysis was performed by manually drawn the whole tumor layer by layer, and texture parameters were recorded. The independent-sample t test and Mann-Whitney U test were used to compare the differences, and the receiver operating characteristic (ROC) curve analysis was used to determine the diagnostic efficiency.Results: With the ROC analysis, 75th, inhomogeneity, and kurtosis provided better diagnostic performance for discriminating ccRCC from chRCC in the arterial phase than those in venous phase (p＜0.05). The entropy performed excellent performance in discriminating ccRCC from chRCC. Kurtosis and entropy performed high sensitivity (91%) and moderate specificity (74%) in discriminating RO from chRCC in the arterial phase. The inhomogeneity of ccRCC was significantly higher than that of RO (p＜0.05), while other parameters showed limited help. Conclusions: The whole-tumor CT texture analysis could be a useful tool for discriminating solid renal tumor, while provided limited help in distinguishing RO from ccRCC which without hemorrhage, necrotic or cystic changes.
Adiponectin ameliorates GMH-induced brain injury by regulating microglia M1/M2 polarization via AdipoR1/APPL1/AMPK/PPARγ signaling pathway in neonatal rats
Authors: Duan Chuanzhi , Xu Ningbo , Li Xifeng , Weng Jun , Wei Chunhua , He Zhenyan , Doycheva Desislava Met , Lenahan Cameron , Tang Wenhui , Zhou Jian , Liu Yanchao , Xu Qiang , Liu Yahong , He Xuying , Tang Jiping , Zhang John H 
Published: February 2022

Abstract
Adiponectin (APN), a fat-derived plasma hormone, is a classic anti-inflammatory agent. Multiple studies have demonstrated the beneficial role of APN in acute brain injury, but the effect of APN in Germinal matrix hemorrhage (GMH) is unclear, and the underlying molecular mechanisms remain largely undefined. In the current study, we used a GMH rat model with rh-APN treatment, and we observed that APN demonstrated a protective effect on neurological function and an inhibitory effect on neuroinflammation after GMH. To further explore the underlying mechanisms of these effects, we found that the expression of Adiponectin receptor 1 (AdipoR1) primarily colocalized with microglia and neurons in brain. Moreover, AdiopR1, but not AdipoR2, were largely increased in GMH rats. Meanwhile, further investigation showed that APN treatment promoted AdipoR1/APPL1-mediated AMPK phosphorylation, and further increased peroxisome proliferator-activated receptor gamma (PPARγ) expression and induced microglial M2 polarization to reduce neuroinflammation and enhance hematoma resolution in GMH rats. Importantly, either knock down of AdipoR1, APPL1, or LKB1, or specific inhibition of AMPK/ PPARγ signaling in microglia abrogated the protective effect of APN after GMH in rats. In all, we propose that APN works as a potential therapeutic agent to ameliorate the inflammatory response following GMH by enhancing the M2 polarization of microglia via AdipoR1/APPL1/AMPK/PPARγ signaling pathway, ultimately attenuating inflammatory brain injury induced by hemorrhage.
Establishment of a rapid and highly effective recycling system for production embryos in 'Chardonnay'
Authors: hao xinyi , Ya Rong , Zhang Tianyue , Kang Benyu , Zhao Ruocen , Xu Weirong 
Published: February 2022

Abstract
Somatic embryo regeneration is an important pathway for mass propagation of grape plants and the basis for grape transgenic technology. The aim of the present study was to establish of a rapid and highly effective recycling system for production embryos in 'Chardonnay'. The white grapevine cultivars 'Chardonnay' was used for the research. Cultured on different media, found that MC and PIV media were beneficial to callus formation of embryonic with 8.60% and 39.52% induction rates, respectively. For cyclic induction of somatic embryos, the CIM medium was conducive to callus formation with 8.33% induction rates. The different concentrations of melatonin on the induction efficiency in somatic embryogenesis and found only MEL2 medium appeared somatic embryos with 5.06% induction rate. Scanning electron microscopy (SEM) revealed that the round spherical granules with full texture and structure were mostly beneficial to callus tissue formation. The study on the cyclic induction of cotyledons, hypocotyls and radicles of somatic embryos showed that the callus induction rate of over 80% of cotyledons and hypocotyls. The reuse abilities of normal embryo (NE), embryo axis elongation embryo (ECE), vitrification embryo (VE) and cotyledon fusion embryo (FCE) were different on somatic embryo cycle induction. Both NE and FCE were induced to form embryonic callus tissue with 8.42% and 4.44% of induction rates, respectively. The results have developed a rapid and highly effective protocol for establishment of a recycling system for production of cyclic embryos in 'Chardonnay'.