bluuebunny/crossref_metadata_2025_split huggingface dataset:
Performance of cement-stabilized weak subgrade for highway embankment construction in Southeast Nigeria
Authors: Ifediniru Chukwuka , Ekeocha Nnamdi E. 
Published: January 2022

AbstractSoils with poor shear strength and high compressibility underlie the wetlands of southern Nigeria. They are susceptible to intolerable settlements and account for greater than 60% of the soils in the region. While requiring embankments for any infrastructure construction, these weak soils pose significant threat to the construction and service life of highway pavements in southeastern Nigeria. Therefore, this research investigates shear strength improvement of a highway embankment’s weak subgrade soil after mass stabilization of soil with 6 and 10% Portland cement. The factor of safety against shear failure of the embankment was analyzed for un-stabilized subgrade and then cement-stabilized subgrade. The analysis was carried out for embankment heights of 4, 5, 6 and 7 m using the limit equilibrium method. Thick soft clayey silt with Cu range of 9 to 15 kPa underlay the embankment, upon improvement, the Cu of 154 and 208 kPa was obtained for 6 and 10% stabilization respectively. The FoS for the embankment on Un-stabilized soil ranged from 0.88 for a 7 m embankment to 1.2 for a 4 m embankment. The FoS after mass stabilization of 1 to 5 m soil ranged between 1.77 and 5.22 for the different embankment heights. Stability was better improved as depth of mass stabilization and cement content increased. A linear relationship was observed to exist between the cement content, strength of the improved soils, stabilization depth and the factor of safety.
A case report of duodenal arteriovenous malformation: usefulness of intraoperative indocyanine green angiography for precise identification of the lesion
Authors: Kurata Yoshihiro , Hayano Koichi , Matsusaka Keisuke , Mamiya Hisashi , Uesato Masaya , Murakami Kentaro , Kano Masayuki , Toyozumi Takeshi , Matsumoto Yasunori , Suito Hiroshi , Isozaki Tetsuro , Ohira Gaku , Hayashi Hideki , Matsubara Hisahiro 
Published: January 2022

Abstract
Background
Arteriovenous malformation (AVM) of the gastrointestinal (GI) tract can cause bleeding. The treatment choice for GI tract AVM is surgical resection of the involved bowel segment with complete resection of the nidus. The AVM formed in the duodenum or pancreatic head could also cause gastrointestinal bleeding, and there are several reports of pancreaticoduodenectomy as its treatment. However, if the area of AVM can be accurately identified during surgery, it may be possible to completely resect the AVM while preserving the organ. We report a case of duodenal AVM in a patient successfully treated with a subtotal stomach-preserving duodenal bulb resection using intraoperative indocyanine green (ICG) angiography technique.

Case presentation
An 18-year-old man was diagnosed with duodenal AVM after several examinations for anemia and was referred to our hospital for further treatment. Preoperative imaging studies showed that the inflow vessels of this duodenal AVM were the inferior pyloric artery and the superior duodenal artery, and the AVM was localized to the duodenal bulb. Thereafter, stomach-preserving duodenal bulb resection preceded by ligation of the inflow vessels was performed. During the surgery, ICG angiography clearly demonstrated the area, where the nidus was distributed, and a duodenal bulb resection with complete resection of the AVM was successfully performed. There was no recurrence at the 6-month follow-up.

Conclusions
Intraoperative ICG angiography was a useful procedure for precise identification of the AVM of the GI tract.
How time-inconsistent preferences influence venture capital exit decisions? A new perspective for grandstanding
Authors: Li Yanzhao , Guo Ju-e , Sun Shaolong , Li Yongwu 
Published: January 2022

AbstractConsidering that the assumption of time consistency does not adequately reveal the mechanisms of exit decisions of venture capital (VC), this study proposes two kinds of time-inconsistent preferences (i.e., time-flow inconsistency and time-point inconsistency) to advance research in this field. Time-flow inconsistency is in line with the previous time inconsistency literature, while time-point inconsistency is rooted in the VC fund’s finite lifespan. Based on the assumption about the strategies guiding future behaviors, we consider four types of venture capitalists: time-consistent, time-point-inconsistent, naïve, and sophisticated venture capitalists, of which the latter three are time-inconsistent. We derive and compare the exit thresholds of these four types of venture capitalists. The main results include: (1) time-inconsistent preferences accelerate the exits of venture capitalists; (2) the closer the VC funds expiry dates are, the more likely time-inconsistent venture capitalists are to accelerate their exits; and (3) future selves caused by time-flow inconsistency weaken the effect of time-point inconsistency. Our study provides a behavioral explanation for the empirical fact of young VCs’ grandstanding.
Money and inflation in Switzerland
Authors: Kugler Peter , Reynard Samuel 
Published: January 2022

AbstractThis paper characterizes the relationship between monetary aggregates, inflation and economic activity in Switzerland since the mid-1970s. Traditional forms of money demand and quantity theory relationships have remained stable over the whole period. Broad money excesses over trend values, accounting for a secular decline in interest rates and thus in trend velocity, have been followed by persistently higher inflation and output with the usual monetary policy transmission lags. Money and exchange rate fluctuations can explain the major inflation developments in Switzerland over the past four decades.
Correlations between body postures and musculoskeletal pain in guitar players
Authors: Portnoy Sigal , Cohen Shlomit , Ratzon Navah Z. 
Published: January 2022

Background
The guitar-playing community is the largest group at risk of developing playing related musculoskeletal disorders. A thorough investigation of the relationships between the various risk factors and players’ report on musculoskeletal pain using objective and accurate means of assessment has yet to be reported.

Purpose
(a) to explore the correlations between demographic characteristics, anthropometric measurements, playing habits, and personal habits of guitar player and their complaints of musculoskeletal pain, (b) explore the correlations between the upper body kinematics of guitar players during playing the guitar and their complaints of musculoskeletal pain, and (c) compare the upper body kinematics of guitar players during playing the guitar while sitting versus standing.

Methods
Twenty-five guitar players (27.5±4.6 years old) filled out questionnaires regarding their guitar-playing habits, and the Standardized Nordic Questionnaires for the analysis of musculoskeletal symptoms. Kinematics of their torso and upper limbs were tracked while they played a tune twice, once while sitting and once while standing.

Results
We found moderate correlations between the number of painful joints in the last year and factors, such as physical comfort while playing, years of playing, and position during playing. During standing, lower back pain severity correlated with the rotation range of the torso, while during sitting, it moderately correlated with the average radial-ulnar deviation of the right wrist. During sitting, we found higher anterior and right tilt of the torso, combined with greater abduction of the right shoulder, higher flexion in the left shoulder and higher radial deviation in the left wrist.

Conclusion
Our results point to several risk factors, related both to playing habits but also to playing posture, which should be considered by the guitar players in order to prevent playing-related musculoskeletal disorders.
Hardware-in-the-loop simulation of DC motor as an instructional media for control system design and testing
Authors: Romdlony Muhammad Zakiyullah , Irsyadi Fakih 
Published: January 2022

Instructional media in control systems typically requires a real plant as an element to be controlled. However, this real plant, which is costly to be implemented, can be replaced by a virtual plant implemented in a computer and modelled in such a way that it resembles the behavior of a real plant. This kind of set-up is widely termed as hardware-in-the-loop (HIL) simulation. HIL simulation is an alternative way to reduce the development cost. A virtual plant is easy to adjust to represent various plants or processes that are widely used in industry. This paper proposes a simple HIL simulation set-up designed as instructional media for design and testing a simple control system. The experimental result on DC motor control shows that HIL simulation dynamical response is similar to the real hardware response with a small average error on measured transient response, represented in 0.5 seconds difference in settling time and 7.43 % difference in overshoot. This result shows the efficacy of our HIL simulation set-up.
In vitro growth and content of vincristine and vinblastine of Catharanthus roseus L. hairy roots in response to precursors and elicitors
Authors: Vu Phuong Thi Bach , Cao Dai Minh , Bui Anh Lan , Nguyen Nhut Nhu , Bui Le Van , Quach Phuong Ngo Diem 
Published: January 2022

Catharanthus roseus L. is a medicinal plant that produces numerous indole terpenoid alkaloids, including vincristine and vinblastine, which are used for cancer treatment. The effect of specified precursors (L-phenylalanine, L-tyrosine) and elicitors (chitosan, methyl jasmonate) on C. roseus hairy roots (CHR) growth has been examined in order to increase the content of vincristine and vinblastine. Our results showed that CHR generated by an Agrobacterium rhizogenes strain isolated in Vietnam was capable of producing both vincristine and vinblastine when subjected to precursors, but only vinblastine when exposed to elicitors. However, both precursors and elicitors were evaluated to have an effect on increasing the accumulation of TIAs in CHR. In particular, the use of elicitors required more time to find the appropriate induction conditions, while the use of precursors gave outstanding efficiency in the treatment with 1 µM phenylalanine. The greatest yields of vincristine (51.99 µg g-1 DW) and vinblastine (699.92 µg g-1 DW) were obtained in the 7th week (with 0.306 g DW biomass). This result is the first time we might boost the levels of vincristine and vinblastine in our CHR clone generated by the Vietnam strain of A. rhizogenes.
THE EFFECTS OF CURRENCY CRISIS ON THE SHARE PRICES OF TURKISH ENERGY COMPANIES
Authors: ORAN Jale , AYDOS Emre 
Published: January 2022

In developing countries, currency crises have become a significant threat. The purpose of the paper is
to examine the volatility of stock prices during the two recent currency crises in Turkey. The selected
companies are the 15 Turkish energy companies listed on the stock exchange.In an atmosphere where
economic uncertainties are growing as a result of globalisation; the exchange rate is one of the most
critical measures and costs. The aim of this study is to reveal its impact on stock prices of Turkish energy
companies. The period of the study covers 12 quarterly periods between 31.03.2018 and 31.12.2020.A
multiple regression model was used to investigate the impact of currency fluctuation on the stock prices of
energy companies operating in Turkey. Our empirical findings show that during the financial crisis, there was no significant relationship between
stock prices and currency rates.
Motivations to enrol in EMI programmes in China: an exploratory study
Authors: Iwaniec Janina , Wang Weihong 
Published: January 2022

Abstract
A recent interest in English Medium Instruction (EMI) has led to the flourishing of studies that examine motivation in EMI classrooms. Some of these studies tend to compare language learning motivation of students who are and are not enrolled in EMI programmes (see e.g. Doiz, Aintzane, David Lasagabaster & Juan Manuel Sierra. 2014. CLIL and motivation: The effect of individual and contextual variables. The Language Learning Journal 42(2). 209–224; Sylvén, Liss Kerstin & Amy S. Thompson. 2015. Language learning motivation and CLIL: Is there a connection? Journal of Immersion and Content-Based Language Education 3(1). 28–50), showing that EMI learners are typically more motivated than their peers in non-EMI contexts. This has led to the common perception that learners enrol in EMI primarily to improve their English. Yet, there is a dearth of comprehensive studies exploring learners’ reasons behind their enrolment in EMI programmes and how these change throughout their studies. To address this gap, 247 university students from a range of universities across China filled in the questionnaire, which included scales pertaining to reasons for choosing an EMI programme. The data were analysed in SPSS. The results show that enhanced future job opportunities, opportunities for contact with an international community as well as potential gains in learning content and language specific vocabulary are the most strongly endorsed drivers that motivate EMI students to undertake their studies in English. They also tend to pursue their ideal visions of themselves as bilingual professionals and derive pleasure from EMI classes. To a lesser extent, students are motivated by what is expected of them and the actual pedagogy in the language classroom. Their motivation tends to stay stable over their years of study. However, the survey also revealed that not all students are equally motivated and resolved to continue with EMI studies. The findings highlight that, whereas students tend to be strongly motivated, there is a potential to improve the delivery of EMI courses.
Fitting procedure for estimating interstellar extinction at high galactic latitudes
Authors: Avdeeva Aleksandra , Kovaleva Dana , Malkov Oleg , Nekrasov Alexey 
Published: January 2022

Abstract
We determine the interstellar extinction in the selected high-latitude areas of the sky based on Gaia EDR3 astrometry and photometry and spectroscopic data from RAVE survey. We approximate the results with the cosecant law in each area thus deriving the parameters of the barometric formula for different lines of sight. The distribution of the parameters over the entire sky is described using spherical harmonics. As a result, we get a mathematical description of the interstellar visual extinction for different lines of sight and distances from the Sun which can be used for estimating interstellar extinction.
The use of chitosan as a skin-regeneration agent in burns injuries: A review
Authors: Sánchez-Machado Dalia I. , López-Cervantes Jaime , Martínez-Ibarra Diana M. , Escárcega-Galaz Ana A. , Vega-Cázarez Claudia A. 
Published: January 2022

Abstract
Chitosan is an amino-polysaccharide, traditionally obtained by the partial deacetylation of chitin from exoskeletons of crustaceans. Properties such as biocompatibility, hemostasis, and the ability to absorb physiological fluids are attributed to this biopolymer. Chitosan’s biological properties are regulated by its origin, polymerization degree, and molecular weight. In addition, it possesses antibacterial and antifungal activities. It also has been used to prepare films, hydrogels, coatings, nanofibers, and absorbent sponges, all utilized for the healing of skin wounds. In in vivo studies with second-degree burns, healing has been achieved in at least 80% of the cases between the ninth and twelfth day of treatment with chitosan coatings. The crucial steps in the treatment of severe burns are the early excision of damaged tissue and adequate coverage to minimize the risk of infection. So far, partial-thickness autografting is considered the gold standard for the treatment of full-thickness burns. However, the limitations of donor sites have led to the development of skin substitutes. Therefore, the need for an appropriate dermal equivalent that functions as a regeneration template for the growth and deposition of new skin tissue has been recognized. This review describes the properties of chitosan that validate its potential in the treatment of skin burns.
Multiple Dependent State Sampling Inspection Plan for Lindley Distributed Quality Characteristic
Authors: Biswas Shovan , Maiti Sudhansu S. 
Published: January 2022

Abstract
This article develops multiple dependent state (MDS) sampling inspection plans based on the mean of lifetime quality characteristic that follows non-normal distributions viz., exponential and Lindley distribution.
In this plan, the lot quality is measured by the lot mean (𝜇).
We have estimated the optimal plan parameters of the proposed technique by non-linear optimization approaches considering acceptable quality level and rejection quality level.
We have compared the sample size between the MDS sampling inspection plan and the single sampling inspection plan for the variable.
Finally, we have taken two examples to illustrate the proposed technique.
A C
0-conforming DG finite element method for biharmonic equations on triangle/tetrahedron
Authors: Ye Xiu , Zhang Shangyou 
Published: January 2022

Abstract
A C
0-conforming discontinuous Galerkin (CDG) finite element method is introduced for solving the biharmonic equation. The first strong gradient of C
0 finite element functions is a vector of discontinuous piecewise polynomials. The second gradient is the weak gradient of discontinuous piecewise polynomials. This method, by its name, uses nonconforming (non C
1) approximations and keeps simple formulation of conforming finite element methods without any stabilizers. Optimal order error estimates in both a discrete H
2-norm and the L
2-norm are established for the corresponding finite element solutions. Numerical results are presented to confirm the theory of convergence.
Performance analysis of wavelength division multiplexing MDM-PON system using different advanced modulations
Authors: Singh Jashanpreet , Kaur Karamjit 
Published: January 2022

Abstract
Mode division multiplexing (MDM) is very competent next generation multiplexing technique and is becoming popular among researchers these days. In this research article, an integrated passive optical network (PON) using MDM and wavelength division multiplexing (WDM) is proposed at 25 Gbps over 3 km multimode fiber (MMF) link distance. For MDM, diverse Laguerre–Gaussian (LG) such as LG12, LG15, LG18, LG111 and LG114 are incorporated and also for cost reduction, vertical cavity surface emitting laser (VCSEL) is located in optical line terminal (OLT). Performance of diverse advanced modulations such as compressed spectrum return to zero (CSRZ), duo-binary return to zero (DRZ) and modified duo-binary return to zero (MDRZ) is evaluated and compared with non-return to zero (NRZ) in terms of Bit error rate (BER) at varied MMF link lengths. Results revealed that CSRZ performance stand out and NRZ provide worst performance.
Searching Probabilistic Difference-Making within Specificity
Authors: Lüchinger Andreas 
Published: January 2022

Abstract
The idea that good explanations come with strong changes in probabilities has been very common. This criterion is called probabilistic difference-making. Since it is an intuitive criterion and has a long tradition in the literature on scientific explanation, it comes as a surprise that probabilistic difference-making is rarely discussed in the context of interventionist causal explanation. Specificity, proportionality, and stability are usually employed to measure explanatory power instead. This paper is a first step into the larger project of connecting difference-making to the interventionist debate, and it starts by investigating whether probabilistic difference-making is contained in the notion of specificity. The choice of specificity is motivated by the observation that both probabilistic difference-making and specificity build on similar underlying intuitions. When comparing measures for both specificity and probabilistic difference-making, it turns out that the measures are not strictly correlated, and so the thesis that probabilistic difference-making is encoded within specificity has to be rejected. Some consequences of this result are discussed as well.
The biomarkers of key miRNAs and gene targets associated with extranodal NK/T-cell lymphoma
Authors: Peng Yin-yin , Zhang Hong-bin , Wang Xin , Xiao Qing , Guo Shu-liang 
Published: January 2022

Abstract
Gene expression profiling studies have shown the pathogenetic role of oncogenic pathways in extranodal natural killer/T-cell lymphoma (ENKL). In this study, we aimed to identify the microRNAs (miRNAs) playing potential roles in ENKL, and to evaluate the genes and biological pathways associated to them. Gene expression profiles of ENKL patients were acquired from the gene expression omnibus (GEO) database. Most differentially expressed (DE)-miRNAs were identified in ENKL patients using limma package. Gene targets of the DE-miRNAs were collected from online databases (miRDB, miRWalk, miRDIP, and TargetScan), and used in Gene ontology (GO) and Kyoto encyclopedia of genes and genomes (KEGG) analyses on Database for annotation, visualization, and integrated discovery database, and then used in protein–protein interaction (PPI) analysis on STRING database. Hub genes of the PPI network were identified in cytoHubba, and were evaluated in Biological networks gene ontology. According to the series GSE31377 and GSE43958 from GEO database, four DE-miRNAs were screened out: hsa-miR-363-3p, hsa-miR-296-5p, hsa-miR-155-5p, and hsa-miR-221-3p. Totally 164 gene targets were collected from the online databases, and used in the GO and KEGG pathway analyses and PPI network analysis. Ten hub genes of the PPI network were identified: AURKA, TP53, CDK1, CDK2, CCNB1, PLK1, CUL1, ESR1, CDC20, and PIK3CA. Those hub genes, as well as their correlative pathways, may be of diagnostic or therapeutic potential for ENKL, but further clinical evidence is still expected.
The crystal structure of C19H20O8
Authors: Lai Bao-Long , Zhou Hai-Ming , Chen Zan-Hong , Chen Hui-Ying , Zhang Qin-Wen , Tao Yi-Wen 
Published: January 2022

Abstract
C19H20O8, triclinic,

P

1
‾

$P\overline{1}$

(no. 2), a = 7.0708(4) Å, b = 8.1261(4) Å, c = 16.1067(6) Å, α = 81.252(4)°, β = 81.500(4)°, γ = 77.890(4)°, V = 887.88(8) Å3, Z = 2, R

gt
(F) = 0.0418, wR
ref(F
2) = 0.1158, T = 150 K.
Automated Detection and Localization of Synaptic Vesicles in Electron Microscopy Images
Authors: Imbrosci Barbara , Schmitz Dietmar , Orlando Marta 
Published: January 2022

AbstractInformation transfer and integration in the brain occurs at chemical synapses and is mediated by the fusion of synaptic vesicles filled with neurotransmitter. Synaptic vesicle dynamic spatial organization regulates synaptic transmission as well as synaptic plasticity. Because of their small size, synaptic vesicles require electron microscopy (EM) for their imaging, and their analysis is conducted manually. The manual annotation and segmentation of the hundreds to thousands of synaptic vesicles, is highly time consuming and limits the throughput of data collection. To overcome this limitation, we built an algorithm, mainly relying on convolutional neural networks (CNNs), capable of automatically detecting and localizing synaptic vesicles in electron micrographs. The algorithm was trained on murine synapses but we show that it works well on synapses from different species, ranging from zebrafish to human, and from different preparations. As output, we provide the vesicle count and coordinates, the nearest neighbor distance (nnd) and the estimate of the vesicles area. We also provide a graphical user interface (GUI) to guide users through image analysis, result visualization, and manual proof-reading. The application of our algorithm is especially recommended for images produced by transmission EM. Since this type of imaging is used routinely to investigate presynaptic terminals, our solution will likely be of interest for numerous research groups.