bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence and specificity of red blood cell alloantibodies and autoantibodies in transfused Iranian β-thalassemia patients
Authors: Rostamian Hosein , Javandoost Ehsan , Mohammadian Mozhdeh , Alipour Abbas 
Published: May 2022

BACKGROUND:
Repeated allogeneic blood transfusions in thalassemia major patients stimulate the patient's immune system to generate antibodies against foreign erythrocyte antigens. This study was carried out to systematically review the findings of available studies about the prevalence of alloantibodies and autoantibodies, as well as the type of causative antigens among transfusion-dependent thalassemia patients in Iran.

METHODS:
Electronic search was conducted on Medline, PubMed, Cochrane, EMBASE, ScienceDirect, and Persians databases. All relevant articles published from January 1990 to July 2018 were included. Abstracts of conference booklets which that been published in the last 5 years were also included in the meta-analysis. The search language was restricted to English and Persian. The quality of studies was evaluated according to a checklist developed by authors, and Cochrane Risk of Bias Assessment Tool was used to evaluate the risk of bias.

RESULTS:
Twenty-three relevant articles met all the inclusion criteria. The prevalence of alloimmunization was 13%. Our study showed that anti-D (25%) and anti-K (25%) were most prevalent among Iranian β-thalassemia patients. Data analysis shows the autoantibody prevalence to be 1% among 3787 patients. Meta-regression revealed that the prevalence of alloantibodies increases with each year as the average age of the study population increases.

CONCLUSION:
The prevalence of red blood cell (RBC) alloantibodies in transfused Iranian β-thalassemia patients was high. Appropriate preventive strategies such as RBC phenotyping for patients before beginning transfusion and using extended RBC donor–recipient matching, specifically for Rh and Kell system, could be implemented to avoid complications in thalassemia patients.
Results of fixation of comminuted Neer type-V distal clavicle fractures by locked plates and coracoclavicular osseo-ligamentous loop sutures
Authors: Khamis Ahmed R. , Shoulah Saad A. 
Published: May 2022

Background
Distal clavicle fractures are less common than mid-shaft fractures with a higher rate of nonunion if displaced. Different methods for fixation exist and each has its advantages and disadvantages. Fixation with anatomically precontoured locked plate with lateral extension proved satisfactory results with minimal complications.

Settings and design
This prospective study was conducted in Banha University Hospital.

Patients and methods
Twenty-three patients with Neer type-V distal clavicular fractures were fixed by distal clavicular locked plate with lateral extension and loop suturing of the coracoclavicular (CC) osseo-ligamentous fragment that is small to be fixed with a screw. The outcome was evaluated clinically by the Oxford shoulder score and radiologically for union, residual deformity, and nonunion through a 12–18-month follow-up period.

Results
The functional outcome was excellent in 19 cases, good in three, and fair in one. Minor complications were reported in six cases including periclavicular hypoesthesia, superficial wound infection, and post-traumatic rotator cuff tendinitis.

Conclusion
The distal clavicle anatomically precontoured the locked plate with lateral extension combined with loop suturing of the small CC osseo-ligamentous fragment that is not amenable for fixation with a screw is an excellent option for fixation of Neer type-V distal clavicle fracture with no need for additional implant to reattach the CC ligaments.
Evaluation of the results of anterior minimally invasive plate osteosynthesis in treating humeral shaft fractures
Authors: Ali Hesham , Yehya Mohamed 
Published: May 2022

Background
The advantages of minimally invasive plate osteosynthesis (MIPO) are less soft tissue dissection and less blood loss with excellent results. This study aims to assess the outcomes of MIPO in treating humeral shaft fractures.

Patients and methods
Anterior MIPO was performed on 30 patients from March 2017 to January 2019. The inclusion criteria for this prospective study included a fracture located at the middle third of the humeral shaft, a fracture with polytrauma, and fractures with early conservative treatment failure. Type A fracture was the most common according to the AO-OTA classification (13 cases), followed by type B (11 cases) and type C (six cases). The space between biceps and brachialis was identified, and a locking compression plate or limited contact dynamic compression plate was used. The minimum follow-up period was 1 year. The outcome measurements included fracture union, alignment, infection, range of motion, functional assessment as per the University of California at Los Angeles shoulder score, and elbow function as evaluated using the Mayo elbow performance index.

Results
The mean operation time was 90.30 min (range, 80–180 min), and mean radiation exposure was 204 s (range, 110—420 s). All fractures united. The mean fracture union time was 15.3 weeks (range, 10–18 weeks). There was no incidence of implant failures. The mean University of California at Los Angeles end-result score was 34 points (range, 32–35). The mean Mayo elbow performance index was 98 points (range, 90–100). The mean range of motion was 135° (range, 100–140°). The functional outcome was satisfactory.

Conclusion
MIPO is an excellent method for treating humeral shaft fractures. It might decrease the perioperative complications with a reduced operation time.
Reduction of butterfly fragments in femur fractures
Authors: Alrasheed Omer 
Published: May 2022

Purpose
e This study compares the outcomes, 6 months postoperative, of femoral fracture interventions featuring nondisplaced and displaced butterfly fragments. The progress of healing, presence or absence of cortical defects, pain score after 6 months, and necessity of revision surgery are measured.

Materials and methods
This is a retrospective cohort study reviewing 100 patients with butterfly femur fractures treated with an intramedullary nail at King Fahad Hospital Hofuf. The patients were divided into two groups: one, of 48 patients, with displaced butterfly fragments after surgery and a second group of 52 patients with nondisplaced butterfly fragments, and all butterfly fragment was not fixed by any method, none of the fragment approximated by close or open reduction methods.

Result
In the first group, 38 patients (79.2%) showed delayed union 6 months after surgery, 30 (62.5%) had a cortical defect, 6 (12.5%) required revision surgery, and 42 (87.5%) still reported feeling pain. In the second group, 8 patients (15.4%) showed delayed union, none had cortical defects, 4 (07.7%) required revision surgery, and 10 (19.2%) reported pain 6 months after surgery.

Conclusion
Displaced butterfly fragments should be reduced to near-anatomical alignment to prevent delayed union, cortical defects, and pain.
A Survey of Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) practices in India
Authors: Madan Karan , Mittal Saurabh , Tiwari Pawan , Hadda Vijay , Mohan Anant , Guleria Randeep 
Published: May 2022

Background:
There is a lack of data on the prevalent practices of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in India.

Aim:
To study the current practices of EBUS-TBNA in India.

Methods:
This survey was an online questionnaire designed on the Google forms interface. The survey included various questions related to demographics, sedation, analgesia and anesthesia, technical aspects, and infection control related to the procedure of EBUS-TBNA.

Results:
Data from 134 respondents (mean age: 42.2 years) were analyzed. Most (97.8%) were pulmonologists or physicians, and a majority (94.8%) practicing in either a private multi-specialty setting or medical college. 40.3% had received procedure training at a formal training program. Mild/moderate sedation was the most common strategy (70.1%). Midazolam (76.7%), Fentanyl (76.0%), followed by propofol (46.5%), were the most frequent drugs, and 82.8% preferred combination sedation. 26.1% used cricothyroid lignocaine injection, and the use of 1% or 2% lignocaine for spray-as-you-go administration was similar. The oral route was preferred, while the laryngeal mask airway was the most common airway conduit under general anesthesia. Suspected granulomatous mediastinal lymphadenopathy (TB/sarcoidosis) (67.2%), followed by lung cancer (32.8%), were the most common indications of EBUS-TBNA. 81.3% performed EBUS-TBNA for lung cancer staging. 21 G needle was preferred (64.9%), and vacuum suction was common (80.6%). 55.2% routinely performed ROSE. Alcohol fixed glass slide smears were the most common method (93.1%) for cytological preparation. 49.3% also performed EUS-B-FNA. 76.9% routinely obtained endo bronchial biopsy and transbronchial lung biopsy in patients with suspected sarcoidosis. Elastography was infrequently used. Nearly three-fourths (77.6%) reused EBUS needles.

Conclusion:
There is practice variability in the multiple aspects related technical performance of EBUS-TBNA. Evidence-based guidelines addressing the multiple technical aspects are required to standardize the practice of EBUS-TBNA.
A multicenter survey study of antifibrotic use for symptomatic patients with post-COVID-19 interstitial lung abnormalities
Authors: Dhooria Sahajal , Maturu Venkata Nagarjuna , Talwar Deepak , Kumar Sachin , Handa Ajay , Agrawal Priya Nath , Jindal Aditya , Tampi PS , Goyal Abhishek , Maskey Dipesh , Aggarwal Ashutosh Nath , Behera Digambar , Jindal Surinder Kumar 
Published: May 2022

Background:
Little data exist on antifibrotic drugs for treating symptomatic patients with persistent interstitial lung abnormalities in the postacute phase of coronavirus disease 2019 (COVID-19). Herein, we describe the physician practices of prescribing pirfenidone and nintedanib for these patients and the physician-assessed response.

Materials and Methods:
This was a multicenter, retrospective survey study of subjects administered pirfenidone or nintedanib for post-COVID-19 interstitial lung abnormalities. Data on the demographic details, comorbidities, abnormalities on the computed tomography (CT) of the chest, treatment, antifibrotic drug use, and physician-assessed response were collected on a standard case record pro forma. We explored physician practices of prescribing antifibrotics (primary objective) and the physician-assessed response (secondary objective).

Results:
We included 142 subjects (mean age, 55.9 years; 16.2% women) at eight centers. The most common abnormalities on CT chest included ground glass opacities (75.7%), consolidation (49.5%), reticulation (43.9%), and parenchymal bands (16.8%). Of the 5701 patients discharged after hospitalization at six centers, 115 (2.0%) received antifibrotics. The drugs were prescribed an average of 26 days after symptom onset. One hundred and sixteen subjects were administered pirfenidone; 11 (9.5%) received the full dose (2400 mg/day). Thirty subjects were prescribed nintedanib; 23 (76.7%) received the full dose (300 mg/day). Of 76 subjects with available information, 27 (35.6%) and 26 (34.2%) had significant or partial radiologic improvement, respectively, according to the physician’s assessment.

Conclusions:
Antifibrotic agents were administered to a minority of patients discharged after recovery from acute COVID-19 pneumonia. Larger, randomized studies on the efficacy and safety of these agents are required.
Assessment of the efficacy of four scoring systems in prediction of acute organophosphorous poisoning outcome
Authors: Shama Wafaa S. , El-Gharbawy Doaa M. , Wahdan Amira A. , Hashem Ahmed A. 
Published: May 2022

BackgroundOrganophosphorous (OP) compounds are one of the major classes of pesticides. In developing countries, acute OP poisoning is a significant health problem due to its high mortality rate.AimThis study aimed to compare the efficacy of four scoring systems: Acute Physiology and Chronic Health Evaluation II (APACHE II), Poison Severity Score (PSS), Rapid Emergency Medicine Score (REMS), and Sequential Organ Failure Assessment (SOFA) score for outcome prediction in acute OP-poisoned cases.Patients and methodsThis cohort study included 100 cases with acute OP poisoning admitted to Tanta University Poison Control Center from the August 1, 2019 to the end of July 2020. The sociodemographic data, clinical examination, and laboratory investigations were recorded. From the collected data, the four scores were calculated for every patient.ResultsThe present study demonstrated that survivors were 92% and nonsurvivors were 8%. About 14% of patients needed intubation, mechanical ventilation, and ICU admission. Regarding prediction of mortality, nonsurvivors had significant higher values of the studied scores than survivors, except for PSS. Furthermore, receiver-operating characteristic curve analysis showed that REMS had the best area under the curve followed by APACHE II score and then SOFA score. Concerning prediction of the need of intubation, mechanical ventilation, and ICU admission, the study recorded statistically significant differences between the two groups regarding all studied scores and REMS had the best area under the curve followed by APACHE II score, SOFA score, and then PSS.ConclusionREMS was the best score for prediction of acute OP poisoning outcome.
The Effectiveness of Moringa (Moringa Oleifera) Bark Extract As A Repellent Against Aedes Aegypti
Authors: Akbar Nyai Harifah , Manurung Imelda F.E. , Regaletha Tadeus A.L. 
Published: May 2022

Demam Berdarah Dengue adalah penyakit tular vektor nyamuk yang sering menimbulkan KLB (Kejadian Luar Biasa) yang menyebabkan kesakitan dan kematian di masyarakat. Salah satu bentuk pencegahan terhadap penyakit DBD adalah pengendalian vektor nyamuk Aedes aegypti. Bentuk pengendalian vektor secara kimiawi adalah yang paling populer, salah satunya menggunakan repellent. Repellent yang beredar di pasaran masih banyak mengandung bahan kimia berbahaya yang dapat mengendap di kulit, juga mencemari lingkungan. Ekstrak kulit batang kelor (Moringa oleifera) dapat digunakan sebagai insektisida nabati yang lebih ramah lingkungan dan tidak meninggalkan zat berbahaya di tubuh. Penelitian ini bertujuan untuk menguji efektivitas kulit batang kelor konsentrasi 15%, 30%, 45%, 60% dan 75% sebagai repellent terhadap nyamuk Aedes aegypti. Metode penelitian yang digunakan yaitu eksperimental murni dengan rancangan penelitian posttest only control group design. Analisis data menggunakan Kruskal Wallis didapatkan hasil P= 0,019 (P< 0,05) yang artinya terdapat perbedaan yang signifikan efektivitas antara 5 kelompok konsentrasi. Rata-rata daya proteksi setiap konsentrasi ekstrak 15%, 30%, 45%, 60%, 75% berturut-turut adalah 88,5%, 91,7%, 92,2%, 100% dan 100%. Hasil hitung rata-rata daya proteksi repellent didapatkan hasil bahwa konsentrasi ekstrak 15% tidak efektif menjadi repellent, sedangkan konsentrasi ekstrak 30%, 45%, 60% dan 75% efektif sebagai repellent nyamuk.
Studi Karakteristik Fasad Arsitektur Kolonial Modern pada Gereja di Jakarta
Authors: Erveline Basri Dian Monica , Sanjaya Ridha , Utami Depiyanah Sri 
Published: May 2022

Abstrak
Suatu peninggalan arsitektur selalu memiliki identitas unik yang jika dicermati dapat menginformasikan banyak hal terutama tentang gaya arsitektur yang mengacu pada kapan bangunan tersebut dibangun. Dalam hal ini, identifikasi karakteristik arsitektur adalah pada bagian fasad bangunan, yang dipilih karena merupakan bagian bangunan yang langsung terlihat dari luar, sehingga merupakan hal pertama yang teridentifikasi. Objek penelitian yang dipilih adalah gereja, sebab merupakan salah satu bangunan yang cukup penting, mengingat fungsinya sebagai tempat ibadah. Untuk lokasi penelitian, dipilih kota Jakarta sebab dianggap dapat mewakili keragaman gereja di Indonesia. Setelah diadakan pengamatan awal, dapat diketahui bahwa gereja di Jakarta sudah ada sejak akhir tahun 1800. Tentunya gereja masa awal ini memiliki karakter arsitektur yang berbeda dengan gereja yang dibangun pada akhir tahun 1900. Mengingat bahwa akhir tahun 1800 adalah masa arsitektur colonial, maka penelitian ini dibuat untuk mengetahui apakah ada kaitan antara karakter arsitektur bangunan (dalam hal ini fasad bangunan) terhadap karakter arsitektur yang ada pada masa itu (gaya arsitektur kolonial). Dalam hal ini, metode penelitian yang digunakan adalah analisis deskriptif kualitatif, dimana studi kasus akan dianalisa elemen fasadnya berdasarkan karakter fasad arsitektur kolonial. Dari hasil penelitian, dapat diketahui bahwa sebagian besar studi kasus memiliki karakter fasad yang sama dengan acuan yang digunakan sebagai arsitektur kolonial. Sehingga dapat disimpulkan bahwa ada kesesuaian antara fasad studi kasus terhadap karakteristik fasad arsitektur kolonial.

Kata kunci: gereja, fasad, kolonial
A INDÚSTRIA DE FRANGO DE CORTE NO MUNDO E NO BRASIL E A PARTICIPAÇÃO DA INDÚSTRIA AVÍCOLA PARANAENSE NESTE COMPLEXO.
Authors: Costa Luciano Souza , Ferreira Garcia Luis Alberto , Alves Brene Paulo Rogerio 
Published: May 2022

o objetivo desse trabalho é realizar uma análise retrospectiva da evolução do setor produtivo de carne de frango de corte no mundo e no Brasil, com ênfase na estrutura da indústria avícola paranaense. Para a execução da pesquisa, utilizaram-se procedimentos metodológicos que incluíram, além da pesquisa bibliográfica e documental, a coleta e a análise de informações e estatísticas obtidas junto a várias instituições como, por exemplo: USDA, IBGE, UBABEF, SINDIAVIPAR, ADAPAR. Os resultados da pesquisa revelaram que a indústria avícola do estado do Paraná-Brasil ocupa um lugar de destaque no cenário nacional e internacional.
Sun Salutation yoga in patients with subacute low back pain: a feasibility study
Authors: Arovah Novita Intan , Kushartanti Wara , Ambardini Rachmah Laksmi 
Published: May 2022

IntroductionThe roles of yoga in improving symptoms in chronic low back pain (LBP) have been established. However, evidence of Sun Salutation yoga feasibility in subacute LBP is lacking. This feasibility study examined the adherence, safety, and potential effect size of Sun Salutation yoga in improving pain, functional disability, and quality of life among patients with subacute LBP.MethodsOverall, 20 patients with subacute LBP (65% females, age: 35 ± 10 years) were enrolled in a 6-week Sun Salutation program. The protocol adherence and safety were self-reported by participants during weekly monitoring. Pain was assessed with visual analogue scale (VAS) and numeric rating scale (NRS), functional disability with Oswestry Disability Index (ODI) and Roland-Morris Questionnaire (RMQ), while quality of life with the Short Form Health Survey (SF-12). Pre- and post-intervention data were analysed by using the paired t-test or Wilcoxon signed-rank test per data distribution. Effect size was evaluated.ResultsAll patients adhered to the study protocol and no adverse effects were reported. Pain, functional disability, and quality of life improved significantly after the intervention. Effect sizes were very large for pain (3.87 and 3.97 for VAS and NRS), functional disability (1.94 and 3.24 for ODI and RMQ), and quality of life (2.34 and 4.62 for SF-12 physical and mental composite score).ConclusionsThe adherence and safety of Sun Salutation yoga in subacute LBP patients were demonstrated, with large effect sizes for improving pain, functional disability, and quality of life. Randomized controlled trials are recommended to confirm the findings.
URGENSI PERENCANAAN PENDIDIKAN PADA LEMBAGA PENDIDIKAN KRISTEN
Authors: Nababan Marina Letara 
Published: May 2022

Planning is the first function in management as a first step before moving to the next action. Planning as a guide in the implementation of education. Educational planning is very important and urgent that must be applied to Christian educational institutions. Planning provides direction for the institution to achieve the vision. In fact, in the observed Christian educational institutions, educational planning has not been made as a necessity that should be carried out before implementing educational programs at the institution. One of the reasons is that educational planners at these institutions still do not understand the planning process comprehensively. The stages of conducting educational planning are: (1) determine the goals, (2) researching the problem to be carried out, (3) collect the necessary data and information, (4) determine a series of actions to be taken, (5) formulating ways to solve problems, (6) determine the human resources that will be involved, and (7) determine how to control and evaluate the plan. Therefore, educational planning must be used as a key factor for Christian educational institutions in determining their goals as an educational institutions that are characterized by Bible teachings as the foundation.
Keywords: planning, educational planning, christian educational institutions
Assessment of blood and productive parameters in mid-lactation dairy cows fed different diets: replacement of corn silage with triticale silage
Authors: Giuliotti Lorella , Benvenuti Maria Novella , Martini Andrea , Accorsi Pier Attilio , Lotti Claudia , Cappucci Alice , Conte Giuseppe 
Published: May 2022

Abstract. Corn crops require large amounts of resources that affect the
environmental sustainability of dairy cow farming systems. The aim of the
study was thus to investigate the effects of the replacement of corn silage
(CS) with triticale silage (TS) by evaluating blood and productive
parameters. The study lasted 7 weeks and involved two groups of 20
Italian Holstein Friesian dairy cows that were homogeneous in terms of
parity (3±1.5), days in milk (DIM) (150±85.0), and daily
milk production (26±4.6 kg). Chemical analysis of feeds was carried out weekly. Dry-matter intake was
estimated daily. At the beginning and end of the trial, haematological,
metabolic, and immunological parameters were analysed. At the same, time
body weight and body condition score were measured. Milk characteristics
were also analysed weekly. Statistical analysis was performed by ANOVA on data of the second sampling, and a non-parametric test was performed to analyse BCS. Regarding the haematological parameters in the two groups, only lymphocyte
values were not in the normal range (2.86 and 2.50×109 L
for CS and TS, respectively). Metabolic parameters were in the normal range
except for blood ureic nitrogen (BUN; 13.65 and 14.04 mg dL−1), non-esterified
fatty acids (NEFAs; 21.40 and 31.93 µmol L−1), and Cl (91.99 and 93.50 mmol L−1). Hair cortisol was low (0.94 and 0.91 pg mg−1), indicating the absence of stress signs, as confirmed by the results
of other immunological parameters (serum
lysozyme (SL), bactericidal activity (SBA), haptoglobin (HP), and oxygen free radicals (OFRs)). Statistical differences were not found either for haematological or
biochemical parameters. The total replacement of CS with TS did not affect
milk yield and composition. In conclusion, the replacement of CS by TS did not give rise to significant
modifications in the parameters investigated and did not alter the health
status of the animals, thus suggesting the feasibility of its introduction
into the diet of mid-lactation dairy cows.