bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cost-effectiveness and cost-utility of an Acceptance and Commitment Therapy intervention vs. a Cognitive Behavioral Therapy intervention for older adults with anxiety symptoms: A randomized controlled trial
Authors: Witlox Maartje , Kraaij Vivian , Garnefski Nadia , Bohlmeijer Ernst , Smit Filip , Spinhoven Philip 
Published: January 2022

Background
A previous randomized controlled trial in older adults with anxiety symptoms found no differences between a brief blended Acceptance and Commitment Therapy (ACT) intervention and brief face-to-face Cognitive Behavior Therapy (CBT) regarding anxiety symptom severity at posttreatment and 12-month follow-up. A health-economic evaluation comparing these interventions has not yet been conducted.

Objective
This study examined the one-year cost-effectiveness and cost-utility of blended ACT compared to face-to-face CBT for older adults with anxiety symptoms.

Methods
The economic evaluation was embedded in a randomized controlled trial comparing blended ACT to CBT in 314 older adults with mild to moderately severe anxiety symptoms. Data were collected at baseline and 3, 6 and 12 months post baseline. For the cost-effectiveness analysis, treatment response was defined as a reliable improvement in anxiety symptom severity (measured with the Generalized Anxiety Disorder-7) between baseline and 12-month follow-up. To assess cost-utility, quality-adjusted life years (QALYs) were computed using EuroQol-5 Dimensions-5 Levels-5 utility scores. Analyses took the societal perspective, including both healthcare costs and productivity costs. Incremental cost-effectiveness ratios were calculated using 2500 bootstraps of seemingly unrelated regression equations of costs and effects. Sensitivity analyses were performed to assess the robustness of the findings.

Results
Differences between the blended ACT group and CBT group in treatment response and QALYs were statistically insignificant and clinically irrelevant. The ACT intervention was associated with an average per-participant cost reduction of €466 ($593) compared to CBT, which resulted from lower productivity costs in the blended ACT group. From a healthcare perspective, the ACT intervention was associated with higher costs (by €71 ($90)) than CBT.

Conclusions
The results do not indicate that from a health-economic perspective blended ACT should be preferred over CBT in the treatment of older adults with anxiety symptoms. The findings support a model of shared decision making, where clinicians and patients collaboratively decide on the preferred intervention, based on ethical-medical, practical and personal considerations.

Trial registration
Netherlands Trial Register: TRIAL NL6131 (NTR6270); https://www.trialregister.nl/trial/6131.
Full evaluation of the psychometric properties of COPSOQ II. One-year longitudinal study on Polish human service staff
Authors: Baka Łukasz , Prusik Monika , Pejtersen Jan Hyld , Grala Krzysztof 
Published: January 2022

PurposeThe aim of the study was the full evaluation of the psychometric properties of the COPSOQ II in one-year longitudinal study on human service staff in Poland. Data were collected from 599 employees representing three occupational groups related to human service work.MethodsCFA was conducted in the structure proposed by the author of the original tool, based on one model, which included 119 observable variables forming 33 latent variables (single item subscales were excluded from analysis). To our knowledge, this was the first complete validation of the entire model using CFA. Reliability analysis was performed using two methods: internal consistency analysis and test-retest analysis. Predictive validity was assessed by correlating COPSOQ II variables with ten criterion variables related to job demands, job resources, work-family conflicts, mental health and well-being.ResultsAccording to the results, CFA supported the original structure of the COPSOQ II. Most of the 33 subscales were characterized by good or very good psychometric parameters. The obtained results confirmed also the fairly high reliability, as well as high convergence validity of all subscales of COPSOQ II.ConclusionThe final conclusion is that COPSOQ II is characterised by satisfactory psychometric properties and could be successfully used to fulfil the demand for reliable and comprehensive assessment methods also in Polish job market settings.
Can women’s 3E index impede short birth interval? evidence from Bangladesh Demographic and Health Survey, 2017–18
Authors: Tuz-Zahura Fatima , Sen Kanchan Kumar , Nilima Shahnaz , Bari Wasimul 
Published: January 2022

Background
Women’s empowerment, education, and economic status are jointly introduced as women’s 3E. A number of studies found the significant association of these three variables with maternal health outcomes, but no studies, to the best of knowledge, have been found to justify the joint influence of women’s 3E on the birth interval. As several studies have revealed that the short birth interval increases the risk of adverse maternal, perinatal, and infant outcomes and it is also responsible for increasing the country’s population size, more research is needed on the birth interval. Therefore, the present study aimed to investigate the influence of women’s 3E on the short birth interval after controlling the other selected covariates.

Methods
Data from the Bangladesh Demographic and Health Survey (BDHS), 2017–18 have been used to serve the purpose of the study. To measure the birth interval, at least two live births for non-pregnant mothers and at least one live birth for currently pregnant mothers born in the 5 years before the survey were included in the study. The Chi-Square test was applied to know the unadjusted association of the selected covariates including women’s 3E with the short birth interval. In order to find out the adjusted association of women’s 3E with the short birth interval, sequential binary logistic regression models have been used.

Results
The study found that about 23% of births in Bangladesh were born in a short birth interval. The likelihood of subsequent births of women decreases with an increase in the score of women’s 3E before or after controlling the characteristics of women, child, and households. The results of the final model show that mothers with the coverage of 50% - 75%, 75% - 100%, and full coverage (100%) in 3E have a 23%, 41%, and 42% lower odds of having short birth interval compared to mothers with coverage of below 50% in 3E, respectively.

Conclusion and recommendation
Bangladesh still lags behind in meeting the minimum requirements for inter-birth intervals set by the World Health Organization. The study has shown that the 3E in women can contribute in prolonging the duration of subsequent births in Bangladesh. Policy-making interventions are needed to raise awareness among uneducated, under-empowered and economically poor reproductive women through family planning and fertility control programs so that the country can achieve the desired fertility rate.
Unequal access to opioid agonist treatment and sterile injecting equipment among hospitalized patients with injection drug use-associated infective endocarditis
Authors: Brothers Thomas D. , Mosseler Kimiko , Kirkland Susan , Melanson Patti , Barrett Lisa , Webster Duncan 
Published: January 2022

Background
Addiction treatment and harm reduction services reduce risks of death and re-infection among patients with injection drug use-associated infective endocarditis (IDU-IE), but these are not offered at many hospitals. Among hospitalized patients with IDU-IE at the two tertiary-care hospitals in the Canadian Maritimes, we aimed to identify (1) the availability of opioid agonist treatment (OAT) and sterile drug injecting equipment, and (2) indicators of potential unmet addiction care needs.

Methods
Retrospective review of IDU-IE hospitalizations at Queen Elizabeth II Health Sciences Centre (Halifax, Nova Scotia) and the Saint John Regional Hospital (Saint John, New Brunswick), October 2015 -March 2017. In Halifax, there are no addiction medicine providers on staff; in Saint John, infectious diseases physicians also practice addiction medicine. Inclusion criteria were: (1) probable or definite IE as defined by the modified Duke criteria; and (2) injection drug use within the prior 3 months.

Results
We identified 38 hospitalizations (21 in Halifax and 17 in Saint John), for 30 unique patients. Among patients with IDU-IE and untreated opioid use disorder, OAT was offered to 36% (5/14) of patients in Halifax and 100% (6/6) of patients in Saint John. Once it was offered, most patients at both sites initiated OAT and planned to continue it after discharge. In Halifax, no patients were offered sterile injecting equipment, and during five hospitalizations staff confiscated patients’ own equipment. In Saint John, four patients were offered (and one was provided) injecting equipment in hospital, and during two hospitalizations staff confiscated patients’ own equipment. Concerns regarding undertreated pain or opioid withdrawal were documented during 66% (25/38) of hospitalizations, and in-hospital illicit or non-medical drug use during 32% (12/38). Two patients at each site (11%; 4/38) had self-directed discharges against medical advice.

Conclusions
Patients with IDU-IE in the Canadian Maritimes have unequal access to evidence-based addiction care depending on where they are hospitalized, which differs from the community-based standard of care. Indicators of potential unmet addiction care needs in hospital were common.
MeToo: The Impact of Rape Culture in the Media, Meenakshi Gigi Durham (2021)
Authors: Anderson Heather 
Published: January 2022

Review of: MeToo: The Impact of Rape Culture in the Media, Meenakshi Gigi Durham (2021)
Cambridge: Polity Press, 191 pp.,
ISBN 978-1-50953-519-4, h/bk, AUD103.95
ISBN 978-1-50953-520-0, p/bk, AUD32.95
ISBN 978-1-50953-521-7, e-book, from AUD18.00
Facebook, Taina Bucher (2021)
Authors: Courty Audrey 
Published: January 2022

Review of: Facebook, Taina Bucher (2021)
Cambridge: Polity Press, 261 pp.,
ISBN 978-1-50953-516-3, h/bk, AUD103.95
ISBN 978-1-50953-517-0, p/bk, AUD32.95
ISBN 978-1-50953-518-7, e-book, AUD36.25
Larrikins, Rebels and Journalistic Freedom in Australia, Josie Vine (2021)
Authors: Van Heekeren Margaret 
Published: January 2022

Review of: Larrikins, Rebels and Journalistic Freedom in Australia, Josie Vine (2021)
Cham: Palgrave Macmillan, 245 pp.,
ISBN 978-3-03061-855-1, h/bk, €74.89
ISBN 978-3-03061-856-8, e-book, €89.99
The Crisis of the Institutional Press, Stephen D. Reese (2021)
Authors: Josephi Beate 
Published: January 2022

Review of: The Crisis of the Institutional Press, Stephen D. Reese (2021)
Cambridge: Polity Press, 214 pp.,
ISBN 978-1-50953-803-4, p/bk, AUD32.95
ISBN 978-1-50953-802-7, h/bk, AUD103.95
ISBN 978-1-50953-804-1, e-book, AUD26.99
Emotions and Virtues in Feature Writing: The Alchemy of Creating Prize-Winning Stories, Jennifer Martin (2021)
Authors: Vatsikopoulos Helen 
Published: January 2022

Review of: Emotions and Virtues in Feature Writing: The Alchemy of Creating Prize-Winning Stories, Jennifer Martin (2021)
Cham: Palgrave Macmillan, 270 pp.,
ISBN 978-3-03062-977-9, h/bk, €89.99
ISBN 978-3-03062-978-6, e-book, €74.89
'Oumuamua: A Mysterious Visitor From Deep Space
Authors: Khalil M. , Said M. , Osman H. , Younis N. , Khaled N. , Amr Y. , A. Mohamed Nour , Ibrahim A. 
Published: January 2022

The mysterious visitor 'Oumuamua is the first interstellar object ever seen in our solar system. It was discovered by the Pan-STARRS tele-scope on 19 October 2017. A short overview of 'Oumuamua is presented in this paper. Moreover, we present this work to spotlight on the fact that, there are trillions of such interstellar objects that could visit our solar system.Â Â
Tracking Comets and Asteroids Using Machine Learning and Deep Learning: A Review
Authors: Khalil M. , Said M. , Ibrahim A. , Gamal M. , A. Mobarak M. 
Published: January 2022

Comets and asteroids are considered as very dangerous objects to Earth. Machine Learning and Deep Learning tools can be used to identify and track such hazardous objects early enough prior to impact. Preparation strategies require several years, so the early detection of such hazardous objects is very crucial aspect. In this paper, the importance of using Machine Learning and Deep Learning to identify and detect asteroids and comets is discussed briefly.Â Â Â
The nutritional potentials and the fatty acid profile of the seed and seed oil of Caesalpinia bonducella
Authors: Adeniyi Adeyeye , Wasiu Kayode Sulaiman , Olakunle Abayomi Akinyode 
Published: January 2022

The physicochemical properties of the seed and fatty acid profile of the seed oil of Caesalpinia bonducella were analyzed in this study, using standard methods of the Association of Official Analytical Chemists (AOAC). The proximate composition was found as follows: Moisture (3.24%), crude fat (41.76%), crude protein (28.63%), crude fibre (4.35%), ash content (2.94%) and carbohydrate (19.08%). The total unsaturated fatty acids (57.36%) was more abundant than the total saturated ones (42.68%). The seed oil had a high level of linoleic acid (28.15%), followed by oleic (18.41%), stearic (13.83%) and palmitic (13.56%). Other fatty acids had less than 10% each. There was a high level of unsaturation (57.36%) with oleic and linoleic acids dominating all other fatty acids with a total of 46.56%. The percentage of essential fatty acids (linoleic & linolenic acids) (32.96%) was also high at about â…“ of the total oil content. The total poly-unsaturated fatty acids (36.99%) was higher than those of mono-unsaturated (20.37%). The high level of poly-unsaturated fatty acids in the oil sample is an advantage as these are essential components of the diet of man. The good total unsaturated/saturated (or P/S) ratio of the oil, (i.e.1.344), makes it to be very nutritionally useful if adopted for domestic purposes.Â Â
Evaluation of essential and heavy metal levels in pasteurized and long-life cow milk
Authors: Atiga Elbagermi Mohamed , Abdulmajid Bin Haleem Antisar , Muftah Elsherif Khaled 
Published: January 2022

In the present investigation, 11 cowâ€™s milk samples (pasteurized and long life) were collected from supermarkets in Misurata city, Libya. For the determination of metal contents, the milk samples were subjected to the optimized microwave digestion method using HNO3 and H2O2. The levels of Na, K, Mg, Ca, Fe, Cu, Cr, Mn, Co, Ni, Zn, Cd, and Pb were evaluated by Microwave Plasma - Atomic Emission Spectrophotometer (MP-AES 4100). It was found that potassium is the most concentrated essential metal while zinc is the highest detected heavy metal in all milk samples. The levels of Co and Cd were not detected in all milk samples under investigation (lower than instrumental detection limits). The mean concentrations of the detected metals were as follows: 828.05Â±0.82, 587.57Â±0.87, 512.38Â±0.30, 73.79Â±0.19, 2.014Â±0.19, 1.89Â±0.16, 0.178Â±0.03, 0.061Â±0.02, 0.074Â±0.01, 0.053Â±0.001, and 0.045Â±0.001 for: K, Ca, Na, Mg, Zn, Fe, Cu, Mn, Ni, Pb, and Cr ppm, respectively. There is no significant difference in the mean concentrations of Ni, Cr and Pb between the investigated milk samples. Though, the levels of essential and heavy metals observed were similar with other reported values in the literature.Â Â
A chemical review on cancer immunology and immunodeficiency
Authors: Heidari Alireza , Schmitt Katrina , Henderson Maria , Besana Elizabeth 
Published: January 2022

Cancer is the most popular reason of death worldwide that many people struggle with it. Although the cancer is dangerous, but if it detects in early stages increases the chance of patient survival. The miRNAs are one of the important ways for early cancer detection that it caused to return an interesting field for researches. All the miRNAs havenâ€™t any role in cancer detection. The Quantum Genetic Algorithm (QGA) is a developed Genetic Algorithm (GA) that by using of quantum computing on top of the genetic algorithm to alleviate the pre convergence problem. The interest of this study is to adopt the QGA for solving of informative miRNAs selection and irrelevant miRNAs removing problem. However, in the suggested algorithm, SVM classifier performance and the dimension of the selected feature vector are dependent on heuristic information for QGA. As a result, the proposed approach selects the adaptive feature subset with respect to the shortest feature dimension and the improved performance of the classifier. The performances of this method are evaluated on the popular data set which the experimental results show that since QGA-SVM is used as one of wrapper methods, as a result, its overall performance is better separation between normal and cancer expression for all types of cancer and better classification rate.Â Â
Synthesis and characterization of pullulan derived hydrogel matrix as carrier for slow release of anti-cancer drug
Authors: Bello Kabiru 
Published: January 2022

The present study is aimed at designing a pullulan based hydrogel through grafting technique for slow release of fluorouracil drug. To achieve this, pullulan grafted acrylic acid was synthesized and characterized by FTIR, and FESEM analyses. Swelling was done in different pH solutions with better swelling in pH 2. As such, the drug loading was done in the specified pH environment. The release profile revealed that more than 90 % of the drug could be released within 5 days. The prepared hydrogel may be considered as stimuli responsive materials for oral drug delivery of anti-cancer drugs.Â Â
Formulation of Paint using Natural Pigment from Lawsonia Inermis Leaves
Authors: Y. Abba Z. , M.Gumel S. , A.Idris A. , A.Ibrahim M. 
Published: January 2022

The increased application of paint in coating industry for interior and exterior decoration and corrosion inhibition, has inspired research in paint formulations. However, due to the toxic effect of preparatory chemicals used in paints, and the restrictive environmental legislation, research efforts have been directed to a more green process. In this work colouring matter from Lawsonia inermis leaves were extracted using water and analyzed by TLC and FTIR spectroscopy. White emulsion paint was formulated using pigment volume concentration (PVC) of 0.07%, the colouring matter extract was dispersed providing colour for the paint. The paint produced with the natural colourant was found to have similar properties with the paint produced using commercial pigment. Paint produced with aqueous extract faded under exposure to 5000 watts Tungsten Lamp after 48 hours but showed excellent fastness to rubbing. The extract induced excellent brownish colouration in the paint which maintained excellent, opacity, adhesion and good water resistance.Â Â Â
Development and validatation of HPTLC method for estimation of irbesartan in bulk and tablet dosage form
Authors: C S Yogeesh , H G Sowmya , Gnana Babu C Jose 
Published: January 2022

A simple, rapid and accurate High performance thin layer chromatography is described for the Development and validation of HPTLC method for Irbesartan in bulk and Pharmaceutical dosage form. The separation is carried out on Merck TLC aluminum sheets of silica gel 60 F254 using Ethyl acetate: Chloroform (6.5:3.5v/v) mobile phase. Quantification was done by Densitometric scanning at 254nm. The linearity was found to be the range of 100-500ng/spot for Irbesartan with the correlation coefficient of 0.9992. The regression equation was found to be Y=7.2733x+703.15. The Rf value of Irbesartan was found to be 0.55. The LOD and LOQ were found to 8.24 and 24.74 respectively. Average recovery was found to be 99.66% which show that the method was free from interference from excipients present in the formulation. Simultaneously the Percentage relative standard deviation was well within the range of 2%. The above method was validated according to the ICH guidelines. The established method enabled accurate, precise and applied to the analysis of Irbesartan in bulk and Pharmaceutical dosage form.Â Â
Hydride generation atomic fluorescence spectrometry (HG-AFS) determination of total arsenic in lipstick
Authors: E. Ghanjaoui M. , Adraoui I. , Gammoun A. , Cervera L. , El Rhazi M. , De la Guardia M. 
Published: January 2022

This study aimed to determine the total arsenic concentration in lipsticks and evaluate the potential health risks due to daily ingestion of this toxic element from this product. The samples were analyzed using atomic fluorescence spectrometry technique after mineralization and hydride generation (HG-AFS). The calibration curve is linear over a concentration range from 0.125 to 2 Âµg L-1 with a regression coefficient of the order of 0.9899. The limit of detection is reaches 3 ng g-1. The standard deviation is of the order of 4%.The accuracy of this method was evaluated by calculating the recoveries of additions of arsenic to three lipstick samples. These results indicate recovery rates between 91% and 98%. Finely, the results found demonstrate that the method used in this work is suitable for arsenic detection in lipsticks samples.Â Â
Development and validation of HPTLC method for the estimation of cefadroxil in bulk and tablet dosage form
Authors: S V Kirankumar , Gnana Babu C. Jose , H G Sowmya 
Published: January 2022

A novel and simple HPTLC method has been developed for the estimation of Cefadroxil (CFD) in bulk and pharmaceutical dosage form on silica gel precoated aluminum 60F254 plates, (10 cm x10 cm) with 0.25 mm thickness. The separation was carried out using ethyl acetate: chloroform (8:2v/v) as mobile phase. The Chromatographic scanning was carried out at 254 nm. The Rf (Â± SD) values were found to be 0.38 Â± 0.05 for CFD. The linearity for analyte was in the range 100-500 ng/band for CFD with correlation coefficients, r2 = 0.9996. The percentage recovery obtained for CFD was in the range of 99.28-100.13% respectively. The proposed method was optimized and validated as per the ICH guidelines17.Â Â
Molecular interaction on imidazolium based ionic liquids and serum albumin: A spectroscopy approach
Authors: Kumar Banjare Manoj , Kumar Banjare Ramesh , Kumar Ghosh Kallol 
Published: January 2022

Interaction between globular proteins with imidazolium based ionic liquids (ILs) is extremely significant considering that of the vast use of ILs, since protein stabilizer in the current years. The present work, the interaction of human serum albumin (HSA) and bovine serum albumin (BSA) with 1-butyl-3-methylimidazolium octylsulphate (BmimOS) and 1-decyl-3-methylimidazolium tetrafluoroborate (DmimBF4) have been examine the use of fluorescence and FTIR. Fluorescence spectra of HSA/BSA are extinguished by BmimOS /DmimBF4 ILs by way of the dynamic method. The various thermodynamic parameters were revealing that very susceptible interactions exist between HSA/BSA and BmimOS /DmimBF4. The conformational adjustments of HSA/BSA were observed by means of FTIR analysis. Fluorescence methods were completed to find out about the thermal balance of HSA/BSA at different temperature. The thermal balance of BSA in the presence of ILs follows the style BmimOS/DmimBF4 and presence of extra hydrophobic IL, decay increases swiftly as a characteristic of concentration.Â Â