bluuebunny/crossref_metadata_2025_split huggingface dataset:
Goodness-of-Fit of wind speed for probability distribution in central western Brazil
Authors: Souza Amaury , Pobocikova Ivana , Oliveira-Júnior José Francisco , Dumka Umesh C , Abreu Marcel Carvalho , Ihaddadene Razika , Cavazzana Guilherme Henrique , Reis Carlos José , Ihaddadene Nabila 
Published: September 2022

Abstract
The adjustment of statistical models to wind speed data makes it possible to know in detail the wind energy potential of a given location, representing a relevant data in the selection of the location for new installations of wind farms. The objective of this study was to evaluate the fit of average wind speed data for Brasilia, Campo Grande, Cuiaba and Goiania in central western Brazil, to the probability distributions functions (PDF) of: GEV, GUM and LN. The statistical criteria, KS, R2, χ2, RMSE, AIC and BIC were considered as judgment criteria to assess the adequacy of PDF. As the main result, the GEV distribution was the one that presented the best result of adjustments to the functions, mainly in the potential of wind energy use and extreme winds that cause felling of trees in the urban environment. These distributions can be used as an alternative distribution that adequately describes the wind speed data in the region. The weakest configurations were obtained by the GUM and LN distributions.
Long-term clinical outcomes and prognostic factors for patients with papillary thyroid carcinoma with other organ invasions after adjuvant radioactive iodine
Authors: Kawamoto Terufumi , Shikama Naoto , Fukumori Tatsuya , Yamada Tetsu , Hoshi Masae 
Published: September 2022

AbstractPurpose:Papillary thyroid carcinoma (PTC) with other organ invasions is directly related to patient prognosis and quality of life; however,studies on the clinical outcomes of adjuvant radioactive iodine (RAI) for PTC with other organ invasions are limited. This study aimed to clarify the clinical outcomes and prognostic factors for patients with PTC with other organ invasions after adjuvant RAI.Methods:Patients with PTC with other organ invasions without distant metastases who underwent surgery and adjuvant RAI were retrospectively reviewed. The initial response based on the American Thyroid Association guidelines and survival rates were evaluated. Prognostic factors for locoregional recurrence-free survival (LRRFS) were analyzed.Results:Between January 2005 and December 2019, 102 patients were included in the study. Their median age was 55 years. The median follow-up duration was 92 months (range; 30–231 months). The excellent response rate after RAI was 42%. The 7-year overall survival, LRRFS, and recurrence-free survival rates were 100%, 75%, and 75%, respectively. Metastatic lymph node size, resection margin status, and post-RAI suppressed thyroglobulin level were the independent prognostic factors for LRRFS.Conclusion:We confirmed that 75% of patients with PTC with other organ invasions could achieve long-term survival without recurrence after adjuvant RAI. Future development of effective treatment strategies for large metastatic lymph nodes, gross residual tumors, and high serum thyroglobulin levels is warranted.
Deep skin diseases diagnostic system with Dual-channel Image and Extracted Text
Authors: Lv Junwei , Li Huanyu , Zhang Peng , Zhang Daojun , Wei Zikun , Qian Tian , Tang Yiqi , Hu Kun , Huang Xianqiong , Xia Xinxin , Zhang Yishuang , Cheng Haixing , Yu Fubing , Zhang Wenjia , Dan Kena , Liu Xuan , Ye Shujun , He Guangqiao , Jiang Xia , Liu Liwei , Fan Yukun , Song Tingting , Zhou Guomin , Wang Ziyi 
Published: September 2022

Abstract
The estimated number of outpatients with skin diseases in China is ~200 million per year, while the dermatologists are insufficient and the doctor-patient ratio remains low, which causes fewer patients receive effective diagnosis. Compared with others, the diagnosis of skin diseases, which is less reliant on laboratory tests, imaging and pathology, needs the assistance of large hardware devices. By contrast, dermatologic diagnosis requires a combination of visual inspection and interrogation frequently which is exactly what Artificial Intelligence (AI) specialises in — Computer Vision (CV), Natural Language Processing (NLP) and Speech Recognition (SR). This allows a simple image capturing tool embedded with an AI model to perform dermatological diagnosis at the primary level. Hence, based on the dataset, which from Asian, with more than 200,000 images and 220,000 medical records, we explored an AI skin diseases diagnosis model---DIET-AI to diagnose 31 skin diseases, covering the majority of common skin diseases. Ranging from 1st September to 1st December 2021, we prospectively collected case information from 15 hospitals in 7 provinces in China, using mobile devices to collect images and medical records of 6043 cases. Then, we compared the performance of the DIET-AI with 6 doctors of different seniority in the prospective clinical dataset, concluding the average performance of the DIET-AI in 31 diseases is no less than that of all different seniority doctors. By comparing the area under curve (AUC), sensitivity and specificity, we demonstrate that DIET-AI model is effective under the clinical scenario. It is further validated under more complex clinical scenarios, providing references for exploring the feasibility and performance evaluation of DIET-AI in clinical use afterwards
Reversible Multi-electron Transfer I-/IO3- Cathode enabled by Hetero-halogen for Ultra-high Energy Density Aqueous Batteries
Authors: Xie Congxin , Wang Chao , Xu Yue , Li Tianyu , Fu Qiang , Li Xianfeng 
Published: September 2022

Abstract
The ever-increasing need for more energy-dense batteries is fuelling global research and innovations in new redox chemistry and device design. Lithium-ion batteries adopting organic electrolytes have the potential to deliver high energy densities, however, they usually have to compromise on safety‒a metric of equal importance. Here, we show an aqueous battery that exhibits a volumetric energy density far beyond the state of the art, together with long cycling life and excellent power performance. The high energy density is realized by employing highly concentrated hetero-halogen electrolytes that contain I- and Br-, which can realize a multi-electron transfer process of I-/IO3- with high reversibility and excellent kinetics. The intermediate bromide species can enhance the reaction kinetics and alleviate overpotential, leading to reversible and fast multi-electron transfer. Using a 6 M halogen electrolyte to achieve more than 30 M electron transfers per litre (the highest reported so far is 9 M), the I-/IO3- cathode displayed super high specific capacity of 830 Ah L-1. A battery with Cd/Cd2+ as anode demonstrated an energy density of >1200 Wh L-1catholyte, which is by far the highest value for aqueous batteries. Even at a current density of 120 mA cm-2 an energy efficiency of 72% can be obtained. Our work demonstrates that safe aqueous batteries with high energy density are possible, offering a new and evolutional option for grid scale energy storage and electric vehicles.
Heterogeneity in cardiovascular deaths or hospitalizations for heart failure from cardiovascular outcome trials is linked to weight: A meta-regression analysis
Authors: GHOSAL Prof SAMIT , Sinha Binayak , Mukherjee Rik 
Published: September 2022

Abstract
Background and aim
Cardiovascular outcome trials with sodium–glucose cotransporter 2 inhibitors (SGLT-2is) have documented a positive impact on micro- and macrovascular complications of type 2 diabetes (T2D). Most analyses suggest that these benefits are independent of achieving metabolic control. This meta-regression analysis was undertaken to explore the relationship between metabolic components positively influenced by SGLT-2is and a reduction in cardiovascular death (CV death) or hospitalization due to heart failure (hHF).
Materials and methods
A database search was conducted using the Cochrane Library to identify relevant studies. Analysis was conducted using CMA and RStudio (2022.07.1) software. The hazard ratios of the individual studies were used to compute the random effects model mean effect size for CV death or hHF, and the prediction interval was used to identify the uncertainty in the summary treatment effect. Heterogeneity was quantified using Q statistics.
Results
A pooled population of 46,969 patients from five studies was included for analysis. The Cochrane risk of bias tool was used to assess the quality of the studies. There was a significant 23% reduction in CV deaths or hHFs in the SGLT-2i arm compared to the placebo arm (hazard ratio (HR): 0.77, 95% confidence interval (CI) 0.70–0.85). However, the prediction interval (0.57–1.05) and the Q statistic (8.06 > degrees of freedom (df) of 4) were indicative of uncertainty in the true effect or heterogeneity. Among the moderators selected, a significant correlation of the outcomes was found with the weight variable (p < 0.01).
Conclusion
The results of this meta-regression analysis suggest that the beneficial effects of SGLT-2is in reducing CV deaths and hHFs are related to the weight variable.
Finerenone in type 2 diabetes and renal outcomes: A random-effects model meta-analysis
Authors: GHOSAL SAMIT , Sinha Binayak 
Published: September 2022

AbstractBackground:The nonsteroidal mineralocorticoid antagonist finerenone is a new addition to the list of agents (angiotensin converting enzyme inhibitors and sodium glucose cotransporter 2 inhibitors) conferring renal protection to patients with diabetic kidney disease. Two recent meta-analyses using the fixed effect model in patients with chronic kidney disease (both diabetic and nondiabetic populations) came to a conflicting conclusion on the effect of finerenone on eGFR decline. This meta-analysis was undertaken exclusively in the type 2 diabetes (T2D) population to explore the robustness and heterogeneity of the effect size by conducting a random effects model meta-analysis along with draft plots and prediction intervals.Materials and methods:A database search was conducted using the Cochrane library to identify relevant citations. Analysis was conducted using RevMan 5.4.1 and R studio RStudio. (2022.07.1, Build 554). The hazard ratio was used as the effect size for the renal composite, while the standardized mean difference (SMD) was used to estimate the effect size of eGFR decline and reduction in the urine albumin creatinine ratio (UACR).Results:A pooled population of 13,943 patients from four citations was included for analysis. The Cochrane risk of bias was used to assess the quality of the studies. There was a significant 16% reduction in the renal composite (kidney failure, a sustained decrease of at least 40% in the eGFR from baseline, or death from renal causes) [HR: 0.84, 95% CI 0.77-0.92, t2: 0, I2: 0%). Finerenone was also associated with reduction in UACR (SMD: -0.49, 95% CI -0.53 to -0.46, t2: < 0.0001, I2: 0%, prediction interval: -0.57 to -0.41) and prevention of decline in eGFR (SMD: -0.32, 95% CI -0.37 to -0.27, t2: < 0.0001, I2: 0%, prediction interval: -0.43 to -0.21) without any evidence for significant heterogeneity. Except for an increase in hyperkalaemia (RR: 2.22, 95% CI 1.93-2.24), adverse events were observed with fineronone compared to placebo (RR: 1.00, 95% CI 0.98-1.01).Conclusion:There are significant benefits in renal outcomes associated with finerenone treatment in T2D patients with established chronic kidney disease with a side effect profile comparable to placebo.
Thermal equation of state of ice-VII revisited by single-crystal X-ray diffraction
Authors: Lai Xiaojing , Zhu Feng , Zhang Dongzhou , Tkachev Sergey , Prakapenka Vitali B. , Chao Keng-Hsien , Chen Bin 
Published: September 2022

Abstract
Ice-VII is a high-pressure polymorph of H2O ice and an important mineral widely present in many planetary environments, such as in the interiors of large icy planetary bodies, within some cold subducted slabs, and in diamonds of deep origin as mineral inclusions. However, its stability at high pressures and high temperatures and thermoelastic properties are still under debate. In this study, we synthesized ice-VII single crystals in externally heated diamond-anvil cells and conducted single-crystal X-ray diffraction experiments up to 78 GPa and 1000 K to revisit the high-pressure and high-temperature phase stability and thermoelastic properties of ice-VII. No obvious unit-cell volume discontinuity or strain anomaly of the high-pressure ice was observed up to the highest achieved pressures and temperatures. The volume-pressure-temperature data were fitted to a high-temperature Birch-Murnaghan equation of state formalism, yielding bulk modulus KT0 = 21.0(4) GPa, its first pressure derivative KT0′ = 4.45(6), dK/dT = –0.009(4) GPa/K, and thermal expansion relation αT = 15(5) × 10–5 + 15(8) × 10–8 × (T – 300) K–1. The determined phase stability and thermoelastic properties of ice-VII can be used to model the inner structure of icy cosmic bodies. Combined with the thermoelastic properties of diamonds, we can reconstruct the isomeke P-T paths of ice-VII inclusions in diamond from depth, offering clues on the water-rich regions in Earth’s deep mantle and the formation environments of those diamonds.
Pemanfaatan Ruang Terbuka Hijau sebagai Area Pertanian Perkotaan pada Jl. Frans Seda Kelurahan Fatululi Kota Kupang – NTT
Authors: Mberu Yuliana Bhara , Rayawulan Robertus M. , Seran Marchiani Rosario 
Published: September 2022

Title: Utilization of Green Open Space as Urban Agricultural Area in Frans Seda Street, Fatululi, Kupang, East Nusa Tenggara

Kupang City is a municipality and capital city of East Nusa Tenggara, has an area of ​​180.27 km2 and an urban population of 423,800 people spread over 6 sub-districts and 51 urban villages. The city of Kupang has the nickname Karang City, because it has an uncertain climate with the dry season relatively longer than the rainy season. The open space between the 2 lanes of the road in Fatululi Village, Oebobo District, is used to grow vegetables by local residents. This is an interesting potential and example as an urban agriculture in the midst of the Covid-19 outbreak. Open space is not only planted with ornamental plants, but also planted with food crops that are beneficial for the food needs of the community. The research target is the potential for more efficient use of green open space to support food needs in urban areas. Qualitative descriptive method was used in this study. This explanation of the use of city open space as an urban area is described in depth to explain the use of open space which is the locus of the study, namely the area of ​​open space in the Frans Seda Street – Fatululi, Kupang area. The method of data collection was carried out by direct observation, conducting interviews with resource persons, and conducting literature studies. The result of this research is the realization of ecological, economic, socio-cultural, and aesthetic functions in this area so that it can support the function of green open space in a sustainable manner.
A review of seawater desalination with membrane distillation: material development and energy requirements
Authors: Adewole Jimoh Kayode , Al Maawali Hilal M. , Jafary Tahereh , Firouzi Amin , Oladipo Habeebllah 
Published: September 2022

Abstract
The importance of membrane technology development in our daily life cannot be overemphasized. Over the past decades, membrane technology has become very popular in providing potable water for mankind. However, old technologies (such as reverse osmosis and ultrafiltration) which are highly energy intensive are still very common in water treatment industries. In this review, the capability of low energy consumption membrane distillation (MD) technology is reviewed with emphasis on material development and energy requirement. We begin by reviewing the history of the MD process, configurations, module types, membrane materials, material fabrication methods, material properties, material modification techniques, application, and energy requirements. Factors which influence the performance of MD – both design and operating conditions – are then extensively discussed. Furthermore, we report desalination and wastewater treatment as the hottest areas of application where MD has gained significant interest. Membrane hydrophobicity and fouling resistance are identified as pivotal areas where improvement in MD performance is being sought. We then discuss various industries where MD is presently being applied. We conclude by highlighting the energy requirements of MD and identify solar energy as a renewable energy resource which could meet the energy requirement of MD technology. It is hoped that this review paper will foster interest in and provide insights on material development for membrane distillation application.
Inalienabilidad como fundamento de la libertad y el derecho indígena al veto. Traducción intercultural en las constituciones de Colombia y Ecuador
Authors: Figueroa Isabela 
Published: September 2022

La inalienabilidad de las tierras indígenas, vigente en las Constituciones de Colombia y Ecuador, puede ser leída como una zona de contacto para el trabajo de traducción intercultural propuesto por Santos. Es un equívoco cultural a ser explorado en el perspectivismo de Viveiros de Castro, permitiendo comunicación entre los sistemas indígenas de tenencia de tierras y el régimen liberal de la propiedad privada. Aunque creadas con la finalidad de transformar las tierras y posesión indígenas, las reglas de inalienabilidad sirvieron como un instrumento para su protección, por lo que su constitucionalización fue reivindicada por los movimientos indígenas de Ecuador y Colombia. Las asambleas constituyentes de los noventas, aunque hayan sido el lugar más adecuado para dar inicio a los diálogos interculturales en el campo de lo que llamamos Derecho, preservan asimetrías de poder porque conservan el marco jurídico liberal. A partir de un ejercicio de traducción intercultural en el campo jurídico, este texto defiende el derecho indígena al veto y propone imaginar un marco de negociación intercultural en cuyo ámbito el Derecho sea visto como un sistema amplio de comunicaciones.
Information security in intelligent mass transit management systems
Authors: Alekseev V. М. , Chichkov S. N. 
Published: September 2022

Aim. The paper examines matters related to the definition of the architecture and requirements for data communication networks as part of intelligent mass transit management systems. Methods. The paper suggests a network architecture using multiprotocol label switching (MPLS) technology and traffic routing. If the core of a local area network is implemented using fully-connected topology, the use of flow labels allows predefining information exchange routes between servers and applications of an information and telecommunications network (ITS). Multiprotocol label switching (MPLS) is the foundation of control and information acquisition networks of ITS. That allows adopting common interfaces to the subsystems that perform various functions within an ITS, e.g., control and diagnostics, minimizing the time of information delivery to management servers and sending critical control commands, as well as using common Ethernet or 4G/5G wireless interfaces. Conclusions. The path installation/removal principle, when applied to critical facilities, significantly complicates attacks and collection of information on the network structure of ITS.
Influência da fragmentação da vegetação em pontos de resgate de fauna nas bacias dos rios Cachoeira e Cubatão em Joinville (SC)
Authors: Vieira Celso , Gabriel Meris Iuri 
Published: September 2022

A destruição e a fragmentação do hábitat natural resultam na aproximação entre o ambiente urbano e o silvestre, no aumento do número de espécies sinantrópicas e na probabilidade de conflito humano-fauna. A paisagem atual da mata atlântica encontra-se fragmentada e desconectada. Sendo assim, o presente estudo objetiva avaliar quais fatores se relacionam com a ocorrência de resgates de fauna realizados em 2020 pelo Corpo de Bombeiros de Joinville (SC), na região da bacia hidrográfica do Rio Cachoeira e da bacia hidrográfica do Rio Cubatão. A avaliação dos pontos de resgate de fauna foi realizada com os dados disponibilizados pelo Corpo de Bombeiros de Joinville, e a análise espacial foi feita no software ArcGIS 10.3. No ano de 2020, resgataram-se 282 espécimes, distribuídos em 10 ordens. As ordens Didelphimorphia e Squamata possuem a maior frequência de eventos, em que os gambás (48,9%) e as cobras (37,6%) somaram 86,5% das ocorrências, e as demais ordens possuem frequência inferior a 3%. O índice de Moran indicou correlação espacial significativa (p<0,01) para distância de vegetação e rios.
Current Naturopathy to Combat Alzheimer’s Disease
Authors: Chakrovorty Arnob , Bhattacharjee Banani , Saxena Aaruni , Samadder Asmita , Nandi Sisir 
Published: September 2022

Abstract:Neurodegeneration is the progressive loss of structure or function of neurons, which may ultimately involve cell death. The most common neurodegenerative disorder in the brain happens with Alzheimer's disease (AD), the most common cause of dementia. It ultimately leads to neuronal death, thereby impairing the normal functionality of the central or peripheral nervous system. The onset and prevalence of AD involve heterogeneous etiology, either in terms of genetic predisposition, neurometabolomic malfunctioning, or lifestyle. The worldwide relevancies are estimated to be over 45 million people. The rapid increase in AD has led to a concomitant increase in the research work directed towards discovering a lucrative cure for AD. The neuropathology of AD comprises the deficiency in the availability of neurotransmitters and important neurotrophic factors in the brain, extracellular betaamyloid plaque depositions, and intracellular neurofibrillary tangles of hyperphosphorylated tau protein. Current pharmaceutical interventions utilizing synthetic drugs have manifested resistance and toxicity problems. This has led to the quest for new pharmacotherapeutic candidates naturally prevalent in phytochemicals. This review aims to provide an elaborative description of promising Phyto component entities having activities against various potential AD targets. Therefore, naturopathy may combine with synthetic chemotherapeutics to longer the survival of the patients.
Relationship Between Handgrip Strength and Age in the Body Composition Variables Among People Living with HIV
Authors: Gouvêa-e-Silva Luiz Fernando , Silva Camila Ferreira , Araujo Izabella Bernardes , Lima Vitória Souza , Fernandes Eduardo Vignoto , Xavier Marília Brasil 
Published: September 2022

Background:The study of aging and handgrip strength (HGS) is important to gain knowledge regarding health care and quality of life in people living with HIV (PLHIV).Objective:The aim of the study is to analyze the relationship between HGS and age in the body composition variables of PLHIV.Methods:The sample consisted of 77 PLHIV, divided into three groups: G40 – PLHIV aged 40-49 years (n=39); G50 – PLHIV aged 50-59 years (n=26); and G60 – PLHIV aged 60-69 years (n=12). Data collection included anamnesis (sociodemographic, clinical, and laboratory information), physical assessment (body composition and HGS), and physical activity level. Data were analyzed by descriptive and inferential statistics.Results:It was noted that men, compared to women, are 5.85 times more likely to present adequate HGS (pp<0.00.001). In addition, adequate HGS was associated with adequate values of body mass index (p<0.001), waist circumference (p<0.001), and fat percentage (p<0.001). The G40 and G50 groups, in relation to the G60, were associated with adequate abdominal circumference (p=0.04).Conclusion:Monitoring the evolution of HGS in PLHIV, over time, makes it possible to infer about body fat and muscle mass, in order to propose prevention actions and guidelines to prevent early muscle loss, the development of overweight/obesity, and abdominal obesity.