bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Pengetahuan, Sikap, Tindakan Terhadap Kesadaran dan PHBS di Nomporejo
Authors: Sarofah Nafidlotul , Handayani Siti Dyah , Nuryakin Nuryakin 
Published: July 2022

Perilaku hidup bersih dan sehat adalah salah satu gambaran kehidupan dari kebiasaan keluarga yang selalu mencermati dan menjaga kesehatan terhadap semua anggota keluarga. PHBS ditempatkan sebagai salah satu indikator pencapaian dalam meningkatkan derajat kesehatan terhadap program Sustainable Development Goals (SDGs) 2015-2030. Pencegahan penyakit yang dilakukan dapat dengan mengurangi atau menghilangkan faktor risiko dengan menerapkan PHBS. Puskesmas Galur II merupakan salah satu Puskesmas yang melakukan peninjauan terhadap Perilaku Hidup Bersih dan Sehat di desa Nomporejo. Pada tahun 2020 cakupan rumah tangga PHBS 16% yang sebelumnya pada tahun 2019 cakupan rumah tangga PHBS 48,67%. Tujuan penelitian ini adalah untuk mengetahui pengaruh pengetahuan, sikap, dan tindakan terhadap kesadaran dan Perilaku Hidup Bersih dan Sehat (PHBS). Teknik pengambilan sampel dengan metode non probability sampling dan penentuan sampel menggunakan purposive sampling. Sampel dalam penelitian ini berjumlah 120 sampel pada kelompok keluarga di Desa Nomporejo Kabupaten Kulon Progo Yogyakarta. Analisis pada penelitian ini dengan menggunakan SEM dengan software AMOS 24.0. Hasil penelitian menunjukkan bahwa pengetahuan berpengaruh signifikan terhadap kesadaran dalam kelompok keluarga. Sikap berpengaruh signifikan terhadap kesadaran dalam kelompok keluarga Tindakan tidak berpengaruh signifikan terhadap kesadaran dalam kelompok keluarga. Kesadaran berpengaruh signifikan terhadap PHBS pada kelompok keluarga. Kesimpulan dari penelitian ini adalah pengetahuan dan sikap berpengaruh signifikan terhadap kesadaran, tindakan tidak berpengaruh signifikan terhadap kesadaran, dan kesadaran berpengaruh signifikan terhadap PHBS.
A Preliminary, Single-Center Retrospective Chart Review of Infusion Times of Intravenous Immune Globulin in Kawasaki Disease and Clinical Outcomes
Authors: Griffin Joseph P. , Powell Angela R. , Bhagat Palak H. , Bartlett Allison H. , Rotolo Shannon M. 
Published: July 2022

OBJECTIVE
Patients diagnosed with Kawasaki disease (KD) are at a high risk of developing coronary artery aneurysms. Intravenous immune globulin (IVIG) given in combination with aspirin is the standard of treatment for the prevention of coronary aneurysm. IVIG is recommended to be administered as a dose of 2 g/kg infused during 10 to 12 hours for the prevention of coronary aneurysms in KD; however, this does not always occur in practice. We aimed to investigate if an infusion time of &lt;10 hours is associated with more coronary artery aneurysms than the recommended infusion time of 10 to 12 hours.

METHODS
Patients with a diagnosis of and treated for KD with IVIG at the University of Chicago Medicine Comer Children's Hospital were identified by drug use reports that included patients who received IVIG between September 2008 and August 2018. Data were collected though chart review and patients were divided into 2 groups based on duration of infusion (&lt;10 hours and 10–12 hours). The primary outcome was the incidence of coronary artery aneurysm. The secondary outcome was the time to defervescence. The safety outcome was the development of renal dysfunction.

RESULTS
A total of 70 patients were screened and 44 were included in the analysis. Coronary aneurysm occurred in 2 of 33 patients (6.0%) in the &lt;10-hour group and no patients in the 10- to 12-hour group (p = 0.558). The median time to defervescence was 0.5 hours in the &lt;10-hour group and 0.95 hours in the 10- to 12-hour group (p = 0.166). The incidence of acute kidney injury was 6% (2 of 33 patients) in the 10-hour group and 9.1% (1 of 11 patients) in the 10- to 12-hour group (p = 0.588).

CONCLUSIONS
All incidences of coronary artery aneurysm occurred in the patients who received IVIG with an infusion time of &lt;10 hours. The incidence of acute kidney injury was numerically higher in the 10- to 12-hour group. Based on the recommendations in the American Heart Association KD guideline, our internal hospital policy, and our results, we recommend the infusion of IVIG be administered at a rate of 10 to 12 hours.
Apropriações da literatura na pesquisa em educação musical: algumas questões
Authors: Nassif Silvia Cordeiro 
Published: July 2022

Este texto, de natureza ensaística, discute a pesquisa em educação musical com foco em questões relativas às formas de apropriação da literatura especializada nos trabalhos. A partir de uma discussão inicial sobre a noção de teoria científica e seu valor acadêmico, discorre também sobre a questão da coerência epistemológica como um dado importante para a confiabilidade da pesquisa. Problematizando o estatuto das diversas fontes bibliográficas mobilizadas em um trabalho investigativo, propõe um modo de organização desse material que permita que as diferentes funções dos diferentes textos usados fiquem explicitadas inclusive no modo de escrita. Sem nenhuma intenção de fornecer um modelo como o melhor, muito menos fechar a questão, acredita-se, porém, que uma preocupação com as questões aqui abordadas poderá qualificar as pesquisas e avaliações de pesquisas na área.
Genetic Variability and Character Association Study for Yield and Attributing Traits in Lentil (Lens culinaris Medikus.) under Terai Agro-climatic Conditions of West Bengal
Authors: Roy Anjan , Sarkar Arup , Roy Suvendu Kumar , Debnath Manoj Kanti 
Published: July 2022

Aims: To evaluate the genotypes for different yields and yield attributing morphological traits by estimation of GCV, PCV, heritability (h2) in a broad sense and genetic advance as percent of the mean. To study the character association between yield and yield attributes and further partitioning into their direct and indirect effect on yield for consideration of appropriate traits to facilitate the selection of desirable genotypes.
Place and duration of Study: Lentil genotypes were evaluated in the instructional farm of Uttar Banga Krishi Viswavidyalaya, Pundibari, Cooch Behar, West Bengal during the rabi season of 2019-2020 and 2020-2021.
Methodology: Forty lentil genotypes including two checks viz., WBL77 and IPL220 were evaluated in alpha lattice design with three replications following the standard cultural practices. The observations were recorded as the average of the same in five randomly sampled plants in each plot for all the eleven attributes studied. Statistical analysis was carried out using the R v. 4.1.1 software.
Results: ANOVA revealed significant variation for all the characters among the genotypes and also for genotype vs. year interaction. Characters such as plant height (96.20%1, 26.32%2), secondary branches plant-1 (91.79%1, 28.59%2), number of pods plant-1 (97.98%1, 89.67%2), pod weight plant-1(g) (96.82%1, 90.15%2), 100 seed weight (g) (98.13%1, 40.92%2), yield plant-1(g) (96.68%1, 91.20%2)and harvest index (%) (94.28%1, 33.06%2) showed high heritability (1) coupled with high genetic advance as percentage of mean(2). Genotypic correlation study revealed that number of pods plant-1 (0.846), primary branches plant-1 (0.905), secondary branches plant-1 (0.416), pod weight plant-1(0.992) and harvest index (0.432) were significantly and positively correlated with yield plant-1. Path coefficient studies revealed that characters like pod weight plant-1(0.699), primary branches plant-1 (0.241), harvest index (0.083), number of pods plant-1 (0.070), 100 seed weight (0.063) and days to 90% maturity (0.047) had positive direct effect on yield.
Conclusion: The present study revealed significant variability among the genotypes as far as the characters taken under study were concerned. Further, the characters showing positive and significant correlation could be considered favorably for a further selection of desirable genotypes.
Expression of insulin‐like growth factor‐I (IGF‐I) and IGF‐II in the avian brain: relationship of in situ hybridization patterns with IGF type 1 receptor expression
Authors: Holzenberger Martin , Lapointe Françoise 
Published: July 2002

AbstractInsulin‐like growth factors (IGFs) are expressed in defined spatiotemporal patterns during the development of the mammalian central nervous system (CNS). Since IGF expression in avian species is less well documented, we studied here the expression of IGF‐I and IGF‐II during chicken CNS development, using in situ hybridization and reverse transcriptase‐PCR, and compared the results with the expression of the IGF type 1 receptor (IGF‐1R). IGF‐II expression started early in embryonic life, shortly after the onset of IGF‐1R expression. During organogenesis, IGF‐II was strongly expressed in kidney, liver and gut primordia, in contrast with IGF‐1R mRNA, which is highly enriched in proliferating neuroepithelia. During the second half of embryonic development, IGF‐I and IGF‐II had distinct expression patterns, suggesting specific roles for each ligand during brain maturation. IGF‐II mRNA was found in numerous brainstem nuclei and in the optic tectum, whereas IGF‐I mRNA was found predominantly in telencephalic regions. Both ligands were expressed in the cerebellum, but each by different cell layers. Some brain regions (olfactory bulb and olivo‐cerebellar system) did not exhibit the postnatal downregulation typical of extrahepatic IGF‐I expression, but continued to express IGF‐I into adulthood. Purkinje cells expressed IGF‐II in the embryo, but switched to IGF‐I expression in the adult. The conservation of embryonic and postnatal IGF expression patterns in the CNS between avians and mammals suggests that the involvement of the IGF system in neurogenesis and differentiation, and possibly in neural plasticity and learning, may have arisen early during tetrapode/vertebrate evolution.
Hyperosmotic Stress and Elevated pCO2 Alter Monoclonal Antibody Charge Distribution and Monosaccharide Content
Authors: Schmelzer Albert E. , Miller William M. 
Published: July 2002

AbstractMedium osmolality increases with pCO2 at constant pH. Elevated pCO2 and osmolality inhibit hybridoma growth to similar extents in both serum‐containing and serum‐free media. The combination of osmolality and elevated pCO2 synergizes to negatively impact cell growth. IgG2a glycosylation by hybridoma cells was evaluated under elevated pCO2 (to 250 mmHg pCO2) and/or osmolality (to 476 mOsm/kg). IgG2a site occupancy did not change significantly under any of the conditions studied, which is consistent with the robust glycosylation of other antibodies produced under various environmental stresses. However, changes were observed in the IgG2a charge distribution. Changes in the isoelectric point (pI) were greater under hyperosmotic stress, increasing by 0.32 and 0.41 pH units at 435 mOsm/kg in serum‐containing and serum‐free medium, respectively. Hyperosmotic stress also resulted in a concomitant increase in the heterogeneity of the charge distribution. The mean pI in serum‐containing medium decreased by 0.16 pH units at 250 mmHg pCO2 when osmolality was controlled at 320 mOsm/kg but increased by 0.20 pH units when the osmolality increased with pCO2 (195 mmHg pCO2–435 mOsm/kg). In serum‐free medium, elevated pCO2 did not alter pI, regardless of medium osmolality. In contrast to elevated osmolality at control pCO2, elevated pCO2 did not significantly alter the IgG2a charge heterogeneity under any of the conditions studied. The IgG2a was not sialylated, so sialylation changes were not responsible for changes in the charge distribution. IgG2a galactose content decreased with elevated osmolality, as a result of either elevated NaHCO3 or NaCl. However, when osmolality was controlled at elevated pCO2, the galactose content tended to increase. The mannose content decreased with increasing stress, while the fucose content remained relatively unchanged. It is likely that the observed increases in the pI of murine IgG2a were due to increased organellar pH, which is reflected by increased specific β‐galactosidase activity in the supernatant.
Wipe test for the detection of indoor allergens
Authors: Polzius R. , Wuske T. , Mahn J. 
Published: July 2002

Background: The determination of house dust mite and cat allergens is a prerequisite for qualified assessment of exposure risk indoors. We describe the validation of integrated wipe tests comprising a porous sampling pin for the collection of settled house dust and an immunochemical test set‐up for specific analysis of dust associated allergens. Methods: Wipe tests comprised an immunochromatographic test system and a porous sampling pin for collecting dust by manually wiping a surface. Two different wipe tests were developed with specificity to cat allergen (Fel d 1) and to dust mite allergen (Der p 2/f 2). One‐hundred and fifty on‐site determinations for each of the allergens in 50 different households completed the field study to validate the analytical system. Reference analysis was based on collection of dust with a vacuum cleaner and analysis of dust associated allergens by ELISA. Results: The wipe tests were found to produce semiquantitative results (class 0–3) on‐site within 10 min of analysis time. For dust mite (cat) allergen the median of class 0–3 was 119 (263), 812 (844), 2708 (5670) and 8000 (56 800) ng/g dust, respectively. With respect to cut‐off levels for dust mite (cat) allergens the clinical sensitivity was 62% (79%) and the clinical specificity was 94% (92%). Conclusions: The wipe tests proved to be a reliable tool for indoor allergen exposure screening, suitable for use even by untrained persons. This may have an impact on compliance with allergen avoidance measures.
Vitamin and mineral supplementation
Authors: Arens Ursula 
Published: July 2002

SummaryIt is the position of The British Dietetic Association that a good quality balanced diet will meet most people's nutritional needs. When people choose to take vitamin/mineral supplements they are advised to select a product formulated in line with dietary reference values to prevent the risk of overdosing, which can occur when high single doses or many supplements are taken.Vitamin and mineral supplements may be recommended for at‐risk groups and in particular circumstances, provided that benefits have been clearly established through scientific evidence. The use of supplements for very specific medical conditions and in situations of acute illness requires medical supervision.State Registered Dietitians (SRDs) have the expertise to provide appropriate advice, support and motivation in this area.
A prospective randomized trial comparing four biofeedback techniques for patients with faecal incontinence
Authors: Heymen S. , Pikarsky A. J. , Weiss E. G. , Vickers D. , Nogueras J. J. , Wexner S. D. 
Published: July 2002

ObjectiveThe aim of this study was to compare four methods of biofeedback therapy for patients with faecal incontinence (FI).Patients and methodsAll patients with FI who were ineligible for surgical management were prospectively randomized using a computer generated randomization method into one of four protocols: 1, out‐patient intra‐anal electromyographic biofeedback training (EMG); 2, EMG plus intrarectal balloon training (BT); 3, EMG plus a home trainer (HT); and 4, EMG, BT and HT. All patients received weekly, 1 h, out‐patient biofeedback training. Success for patients with FI was measured by a reduction in incontinent episodes (days/week). In all instances, patients maintained a daily log in which documentation was recorded regarding each bowel evacuation.ResultsForty patients were randomized into one of the four groups. Six patients withdrew after one session and were not included in the analysis. Therefore, 34 patients (23 female and 11 male) with a mean incontinence score of 12 (range 7–14) were randomized to one of the four groups (n=8, 8, 8, and 10, respectively). There was a statistically significant reduction in incontinent episodes for all groups. However, there were no significant differences in treatment outcome found in comparisons among the four groups.ConclusionBiofeedback therapy significantly improves FI. Moreover, EMG training was as effective alone as was the addition of HT, BT or both for the treatment of FI.
An appraisal of the disc–macula distance to disc diameter ratio in the assessment of optic disc size
Authors: Barr D.B. , Weir C.R. , Purdie A.T. 
Published: July 2002

SummaryThe disc–macula distance to disc diameter ratio (DM:DD ratio) has been advocated as a method of supporting the diagnosis of optic nerve hypoplasia. A DM:DD ratio of 3.00 has been claimed to be a satisfactory threshold value for this purpose. This study has critically evaluated the above claim and found a value of 3.00 to be too low. The threshold DM:DD ratio values for the diagnosis of unequivocal ONH for an adult population, 5 and 2 years of age were found to be respectively 4.20, 3.93 and 3.70, the values for the diagnosis of mild ONH being 3.68, 3.44 and 3.23. Lower computed values reduce the predictive power. The method of computation of the DM:DD ratio was modified to abolish potential error due to disc rotation and foveal displacement. In an adult population, there was no correlation between the DM:DD ratio and amblyopia or disc ovalness. There was a trend of increasing DM:DD ratio towards myopia and decreasing DM:DD ratio towards hypermetropia; the DM:DD ratio may therefore be falsely high in high myopia. DM:DD ratio values below threshold should therefore be interpreted with care until formal optic disc biometry can be performed.
JUVENILE, AUTOSOMAL DOMINANT, DISTAL SPINAL MUSCULAR ATROPHY AND NEUROSENSORIAL DEAFNESS NOT LINKED TO CHROMOSOME 12q24
Authors: De Angelis M.V. , Stuppia L. , Passamonti L. , Palka G. , Gambi D. , Uncini A. 
Published: July 2002

Distal spinal muscular atrophy, also classified as a spinal form of Charcot‐Marie‐Tooth‐disease, or distal hereditary motor neuropathy, is genetically heterogeneous and both autosomal dominant and autosomal recessive inheritance have been described. Recently, in an autosomal‐dominant Belgian family with juvenile onset in distal leg muscles, a significant linkage was obtained with markers located at chromosome 12q24 (Timmermann et al. 1996).We describe a three‐generation Italian kindred with distal spinal muscular atrophy showing autosomal dominant inheritance, onset at 8–10 years with leg weakness and atrophy, later involvement of distal arm muscles, and eventually proximal muscles. The older patients also had neurosensorial deafness. To confirm the previous genetic findings, we used four microsatellite markers located at chromosome 12q23‐24: D12S86, D12S1612, D12S1349, PLA2A. No support for linkage with 12q24 was found in this family, which indicates a genetic heterogeneity in juvenile onset autosomal dominant distal spinal muscular atrophy.
ROSS SYNDROME: CLINICAL AND LABORATORY EVALUATION OF TWO CASES
Authors: De Joanna G. , Perretti A. , Tugnoli V. , Nolano M. , Cruccu G. , Santoro L. 
Published: July 2002

We describe two males, aged 41 and 55, come to our observation complaining of heat intolerance, abnormal increase in body temperature with minimal exercising, reduced sweating and, generalized fatigability; one of them had distal paresthesias. Neurologic evaluation showed bilateral Adie's tonic pupil and an absence of deep‐tendon jerks. A diagnosis of Ross' Syndrome was advanced. Autonomic tests, nerve conduction study, H‐reflex, computerized termoregulatory and pain thresholds, laser CO2 cortical evoked potentials, and skin biopsy were performed. One of them performed a histamine test and hand photopletismography resulted positive for sympathetic impairment, and pilocarpine pupil test that showed a parasympathetic denervation hypersensitivity.The following tests gave the same results in both patients: parasympathetic and most sympathetic tests were normal. Sympathetic skin response was absent and Minor test showed an almost complete absence of sweating. Sweating was possible only in two or three small areas. Positive pilocarpine test suggested a postganglionic involvement of sympathetic nervous system. Sensitive and motor nerve conduction velocities were normal, while H‐reflex was not detectable. Termoregulatory and pain thresholds were abnormal. Laser CO2 cortical evoked potentials showed the absence of C fibre potentials, whereas A‐δ fibres response was abnormal in one of them. Hairy skin biopsy showed a definite reduction of sweat glands and of small vessel innervation; glabrous skin biopsy performed in one of them showed a reduced number of Meissner corpuscles. These findings suggest that in Ross' Syndrome the degenerative process can involve, besides the autonomic fibres, myelinated somatosensory fibres also.
Electronic states of CuO
Authors: Madhavan P. V. , Newton M. D. 
Published: July 2002

A b initio SCF and CI calculations are reported for the ground state and low-lying excited electronic states of CuO (i.e., within ∼20×103 cm−1 of the X̃ 2Π ground state), employing an ab initio effective potential for the Cu atomic core (1s–3p), and including comparisons of several atomic orbital basis sets. The calculated bond lengths, energy separation, and population analyses for the lowest two electronic states, X̃ 2Π and Y 2Σ+ [corresponding roughly to Cu+ (3d10) and O− (2p5), where the 2p oxygen hole is, repectively, 2pπ and 2pσ], do not vary appreciably among the basis sets tested (minimal and split valence bases on Cu, and a split valence basis on oxygen, with and without d-polarization functions and diffuse p functions on oxygen) and are in reasonable agreement with previous experimental and theoretical estimates. Most of the remaining excited states of CuO below ∼20×103 cm−1 may be rationalized in terms of atomic-like excitations originating from the
X̃ 2Π ground state: 3d(Cu) → 4s(Cu) and 3d(Cu) → 2 pπ (O) (the latter formally corresponds to Cu2+O2−, though covalent 2p‘gs–4s bonding reduces the charge to ∼Cu+O−). Close agreement (rms deviation of ∼103 cm−1) is obtained between calculated (CI) and observed adiabatic transition energies for ten Σ, Π, and Δ doublet excited states (relative to the X̃ 2Π state), after the calculated excitation energies are reduced by ∼5×103 cm−1, a term which corrects primarily for limitations in the Cu atom basis set, and whose magnitude can be obtained both in terms of calculated and observed atomic quantities and by direct least-squares fitting of calculated and observed CuO transition energies. The calculations yield the first comprehensive assignment of Kronig symmetry (±) for the observed 2Σ states (δ 2Σ−, A 2Σ−, A′ 2Σ+, and G 2Σ+) and one which is consistent with recent analyses of experimental data. The extent of specific molecular correlation effects is analyzed, and found to be important in the assignment of several of the observed transitions. The CI mixing of different principal configurations may be significant for states involving the ‘‘Cu2+O2−’’ configuration (as also suggested in previous studies), and the assignments based on the present CI results for these states are only tentative.