bluuebunny/crossref_metadata_2025_split huggingface dataset:
Grain yield and yield component trait association and salinity tolerance of rice lines under mild saline stress condition
Authors: Nafisah  , Sitaresmi T. , Gunarsih C. , Hairmansis A. 
Published: February 2022

Abstract
The research was aimed to study yield and yield component trait association and salinity tolerance of rice genotypes under mild saline stress condition. The activity was done in Soge, Kandanghaur Indramayu district, West Java Indonesia, from July to November 2020. The material consisted of 150 genotypes including sixteen check varieties represented high yield popular rice varieties and salinity tolerance rice varieties. The alpha lattice design with two replications with a 4 m2 plot size was used in this experiment. A total of three seedlings that was twenty-one days old was manually transplanted in one hole with a 25 x 25 cm planting space. The result showed that under mild saline stress condition, there was no association between grain yield and salinity tolerance at the seedling stage. The grain yield positively correlated with a tolerance of genotype at the vegetative stage, plant height, tiller number, spikelet fertility and negatively associated with unfilled grain number. These traits can be used as indirect selection criteria for high grain yield under mild saline stress condition.
Prospect of sorghum development as corn substitution in Indonesia
Authors: Pujiharti Y , Paturohman E , Ikhwani  
Published: February 2022

Abstract
This paper explores the opportunities for the development of sorghum to reduce imports of corn. Besides being the primary raw material for poultry feed, corn is the second staple-food ingredient after rice. Still, the increase in corn production is not in line with the demand for corn due to the increasing population. This condition has resulted in the need for corn to be imported, while the government has imposed an import ban since 2017. It is necessary to have other commodities that can substitute corn as food as sorghum. Sorghum farming produces not only sorghum seeds but also plant waste which can use for a ruminant feed so that the availability of ruminant feed continues. Sorghum farming needs to be developed so that the availability of food and feed can sustain. The development of sorghum should be in areas where there is a feed industry to ensure the sorghum market for farmers and the availability of raw materials. The development can also be in areas that have long consumed sorghum (local food).
Competitiveness analysis of Indonesian processes and non-processed agricultural commodities in the ASEAN Region
Authors: Tety E , Kurnia D , Andriani Y 
Published: February 2022

Abstract
The commitment of the ASEAN Economic Community opens opportunities up for member countries including Indonesia to improve the trade balance, especially in processed and non-processed agricultural products. These opportunities should be followed by increasing the competitiveness of each country. The purpose of this study was to analyze the development of exports of processed and non-processed Indonesian agricultural products in the ASEAN region and the competitiveness of exports of agricultural products in ASEAN countries to the main destination countries. TSI analysis was used to determine the development of exports, while the Constant Market Share (CMS) and Revealed Comparative Advantage (RCA) approaches are used to analyze the competitiveness and competitive advantages of each ASEAN member country. The results showed that Indonesia was in the top position for the export of agricultural processed products in 2009 with a TSI reaching 0.87. Whereas non-processed agricultural products led by Thailand with TSI reached 0.89. Increased competitiveness of processed and non-processed products is more influenced by increased demand in export destination countries. The RCA index of non - processed agricultural products in Thailand reached a peak in 2014 at a 3.2 position, while Indonesia had the highest RCA index in agricultural processed products which reached 8.80. This shows that Indonesia has comparative advantages in agricultural processed products compared to other countries in ASEAN.
Utilization of tofu waste from Indonesian small scale industry as fish feed through a fermentation process
Authors: Mulyasari  , Subaryono  , Yosmaniar  
Published: February 2022

Abstract
Tofu waste is a by-product from the soybean processing industry like tofu and tempeh in Indonesia. The high amount of waste from tofu processing creates problems for the environment, both in aesthetics and odor. Therefore, the utilization and treatment of waste from tofu processing industry activities is needed to reduce the negative impact of the resulting waste. One of them is to use it as a raw material for fish feed. Tofu waste has a good nutrient content (protein content is around 21.3 - 27%), so a potential source of fish raw material. However, tofu waste has low digestibility because of its high fiber (16-23%) and antinutrient substances content. Therefore, improving the quality of tofu waste by fermentation was needed. Fermentation can change a substrate or raw material into the desired product with better quality. It can reduce the levels of crude fiber, increase digestibility, and increase levels of soluble protein and crude protein from raw material. This research aimed to evaluate the quality of tofu waste fermented using Bacillus sp PAS7 as raw material for fish feed production. This research used a completely randomized design (CRD) with four treatments and three replicates. The treatment for determining inoculum doses used concentrations of 0, 2, 4, and 6% per gram (weight) of tofu waste (v / w). The time of the fermentation process was three days at 37oC. The parameters measured were reducing sugar, dissolved protein, proximate analysis, and in vitro protein digestibility. The results showed that tofu waste fermentation using Bacillus sp PAS7 isolate improved the nutrient quality of the material. It can be seen from the increased levels of dissolved glucose and protein, decreased fiber content, and increased in vitro protein digestibility. Fermentation using Bacillus sp PAS7 with a dose of 2% was adequate to improve the quality of tofu waste.
Potential use of Lactiplantibacillus plantarum strains for fermentation of fat milk
Authors: Nikitina E 
Published: February 2022

Abstract
The ability of potentially probiotic strains Lactiplantibacillus plantarum AG9 and AG10 to influence the quality of fat cow’s milk was studied. It was found that L. plantarum strains AG9 and AG10 showed high coagulation ability, actively ferment lactose and accumulate lactic acid. The strain Lactiplantibacillus plantarum AG10 is able to reduce the level of fat during fermentation, which is a show of lipotolytic effect. The texture characteristics of fermented milk produced with the use of these strains are excellent. L. plantarum strains both during and after fermentation survived well in fermented milk, indicating that the milk medium is a suitable substrate for this species. The results obtained at this stage of the study indicate the promising use as a co-culture in the technology of sour milk products.
Mapping of sustainable warehouse process in the agro-hub Banten using business process modelling notation
Authors: Wahyuni F D , Najah Z , Santoso M I 
Published: February 2022

Abstract
Study of sustainable warehousing management through modelling process bussiness in Agro-hub was needed as issue of environmentally-friendly way of warehouse management appeared. Agro-hub was distribution centre integrated with logistics, warehouses, packaging houses and digital markets. Warehouse processes include receiving, data records, packing, and inventory and logistics. This researched was aimed to designed sustainable warehouse process in the Agro-hub Banten. The modelling method was using Business Process Modelling Notation. The collecting data was done by observation, in-depth interview and documentation review. Results of this study are mapping of material acceptance process (purchasing), dara record process, and inventry and packing practices.
Predicting personalised and progressive adaptive dose escalation to gross tumour volume using knowledge-based planning models for inoperable advanced-stage non-small cell lung cancer patients treated with volumetric modulated arc therapy
Authors: Tambe Nilesh S , Pires Isabel M , Moore Craig , Wieczorek Andrew , Upadhyay Sunil , Beavis Andrew W 
Published: February 2022

Abstract

Objectives. Increased radiation doses could improve local control and overall survival of lung cancer patients, however, this could be challenging without exceeding organs at risk (OAR) dose constraints, especially for patients with advanced-stage disease. Increasing OAR doses could reduce the therapeutic ratio and quality of life. It is therefore important to investigate methods to increase the dose to target volume without exceeding OAR dose constraints. Methods. Gross tumour volume (GTV) was contoured on synthetic computerised tomography (sCT) datasets produced using the Velocity adaptive radiotherapy software for eleven patients. The fractions where GTV volume decreased compared to that prior to radiotherapy (reference plan) were considered for personalised progressive dose escalation. The dose to the adapted GTV (GTVAdaptive) was increased until OAR doses were affected (as compared to the original clinical plan). Planning target volume (PTV) coverage was maintained for all plans. Doses were also escalated to the reference plan (GTVClinical) using the same method. Adapted, dose-escalated, plans were combined to estimate accumulated dose, D99 (dose to 99%) of GTVAdapted, PTV D99 and OAR doses and compared with those in the original clinical plans. Knowledge-based planning (KBP) model was developed to predict D99 of the adapted GTV with OAR doses and PTV coverage kept similar to the original clinical plans; prediction accuracy and model verification were performed using further data sets. Results. Compared to the original clinical plan, the dose to GTV was significantly increased without exceeding OAR doses. Adaptive dose-escalation increased the average D99 to GTVAdaptive by 15.1Gy and 8.7Gy compared to the clinical plans. The KBP models were verified and demonstrated prediction accuracy of 0.4% and 0.7% respectively. Conclusion. Progressive adaptive dose escalation can significantly increase the dose to GTV without increasing OAR doses or compromising the dose to microscopic disease. This may increase overall survival without increasing toxicities.
The role of trust in public acceptability of energy projects: Integrity versus competence
Authors: Liu Lu , Vrieling Leonie , Perlaviciute Goda , Bouman Thijs , Steg Linda 
Published: February 2022

Abstract
Public acceptability of energy projects depends on people’s trust in agents responsible for those projects. We examined to what extent different dimensions of trust, notably integrity- and competence-based trust, are associated with public acceptability of real ongoing energy projects associated with acute risks and other consequences. A series of questionnaire studies in the Netherlands revealed that both integrity- and competence-based trust were positively associated with public acceptability of natural gas extraction which causes earthquakes in the region. Yet, integrity-based trust was more strongly and consistently associated with public acceptability of the natural gas extraction compared to competence-based trust. The findings were rather consistent across four different measurement phases. We discuss the theoretical and practical implications of our findings.
Recent developments in RAM based MWCNT composite materials: a short review
Authors: Yeswanth I V S , Jha Kanishka , Bhowmik Shantanu , Kumar Rajeev , Sharma Shubham , Ilyas R A 
Published: February 2022

Abstract
The need to develop radar absorbing materials (RAMs) that meet the structural requirement of defense applications is growing swiftly, due to the extensive use of electromagnetic waves in Radar. With the major developments and extensive use of Radar in military applications, the role of Radar absorbing, light weight and high strength structures has become a prime objective for researcher working on the development of RAMs. Various composites have been developed by using reinforcements which are dielectric, such as carbon nanotubes (CNT), magnetic materials like ferrites, that have been extensively used for reinforcement when developing RAMs. Ferromagnetic materials have a high density and can only achieve a narrow bandwidth of absorption. CNT have very good electrical, mechanical and thermal properties and can achieve high dielectric losses but their complex synthesis process is a barrier to commercial applications. Research on reinforcing multi-walled carbon nanotubes (MWCNT) with ferrites and metal oxides can also be extended to the study of thermoplastic polymers like polyether ether ketone and polyaryletherketone, which are gaining prominence in aeronautical applications, owing to their superior mechanical and low moisture absorbing properties. Further research can be carried out on reinforcing metal oxides, as metal oxides, when reinforced with MWCNT enhance the dielectric properties which improve the reflection losses as reported in a few studies.
Historians and Their Publics, Then and Now
Authors: Jones Jacqueline 
Published: February 2022

Abstract
The American Historical Association annual presidential addresses provide evidence of transformations in the profession and the discipline from the founding of the association in 1884. It was not until the late 1970s that AHA presidents began to explore the histories of women and people of color in any depth; before then, addresses gave short shrift to whole swaths of the human population, and many of these talks promoted a triumphalist view of United States history. Today people outside the academy encounter cutting-edge historical scholarship by way of their daily newspaper, blogs and online news sites, TV and films, the Broadway stage, historic places, debates over renaming streets and removing statues, and genealogy projects. At the same time, historians face challenges from budget-cutting administrators (in universities, libraries, and museums) and from cynical politicians who seek to replace truth with myth, in the process roiling state legislators and members of local school boards. Consequently, historians today contend with two major opposing forces—on the one hand, a proliferation of lively venues that bring inclusive stories about the past to a wider audience, and, on the other, political conditions that lead to the intimidation of historians regardless of where they work. In the face of these challenges, the AHA must continue its robust advocacy work on behalf of all historians.
Fused Lateral Clitoral Hood and Labia Minora: New Classification Based on Anatomic Variation of the Clitoral Hood–Labia Minora Complex and Simple Surgical Management
Authors: Xia Zenan , Liu Chang-Yi , Zhang Mingzi , Zhang Yuwei , Guan Ai , Li Yunzhu , Yu Nanze , Liu Zhifei , Zeng Ang , Si Loubin , Long Fei , Long Xiao , Zhu Lin 
Published: February 2022

Abstract

Background
Existing classifications of the clitoral hood–labia minora complex (CLC) have neglected its integrity and anatomic variation, resulting in failure to optimize approaches tailored to individuals.

Objectives
The aim of this study was to present a new classification system for comprehensive evaluation of variations of the CLC and to introduce a simple surgical approach for the fused type.

Methods
Anatomic variations of the CLC were classified into 3 types: isolated labia minora or lateral clitoral hood hypertrophy (Type 1); conventional combined hypertrophy (Type 2); and fused lateral clitoral hood and labia minora (Type 3). A modified procedure for the fused type was performed in 4 steps: the anterior border of labia minora was defined first, then the hypertrophic lateral clitoral hood and labia minora were each removed separately, and finally the junction region was trimmed. Satisfaction questionnaires were administered during follow-ups.

Results
Among all 301 patients (602 sides), Type 2 was the most common variation (285 sides, 47.3%). Type 3 variations in 67 patients (105 sides, 17.5%) were identified, and 77.6% of these patients answered the questionnaires 3 months after surgery. For patients with type 3 variations, the satisfaction rate in the 4-step excision group was 91.7%, which was significantly higher than that in the wedge excision group (56.3%) (P = 0.01). The complication rate of the 4-step excision was 2.5%.

Conclusions
Preoperative evaluation based on the new classification facilitated recognition of variations of the CLC, especially of the fused type. The 4-step excision is a simple, effective, and safe approach to treat the fused variation with high satisfaction.

Level of Evidence: 4
FitDock: protein–ligand docking by template fitting
Authors: Yang Xiaocong , Liu Yang , Gan Jianhong , Xiao Zhi-Xiong , Cao Yang 
Published: February 2022

AbstractProtein–ligand docking is an essential method in computer-aided drug design and structural bioinformatics. It can be used to identify active compounds and reveal molecular mechanisms of biological processes. A successful docking usually requires thorough conformation sampling and scoring, which are computationally expensive and difficult. Recent studies demonstrated that it can be beneficial to docking with the guidance of existing similar co-crystal structures. In this work, we developed a protein–ligand docking method, named FitDock, which fits initial conformation to the given template using a hierarchical multi-feature alignment approach, subsequently explores the possible conformations and finally outputs refined docking poses. In our comprehensive benchmark tests, FitDock showed 40%–60% improvement in terms of docking success rate and an order of magnitude faster over popular docking methods, if template structures exist (&gt; 0.5 ligand similarity). FitDock has been implemented in a user-friendly program, which could serve as a convenient tool for drug design and molecular mechanism exploration. It is now freely available for academic users at http://cao.labshare.cn/fitdock/.
Precise paternal ancestry of hybrid unisexual ZW lizards (genus Darevskia: Lacertidae: Squamata) revealed by Z-linked genomic markers
Authors: Yanchukov Alexey , Tarkhnishvili David , Erdolu Meriç , Şahin Mehmet Kürşat , Candan Kamil , Murtskhvaladze Marine , Gabelaia Mariam , Iankoshvili Giorgi , Barateli Natia , Ilgaz Çetin , Kumlutaş Yusuf , Matur Ferhat , Çolak Faruk , Arakelyan Marine , Galoyan Eduard 
Published: February 2022

Abstract
We genotyped multiple populations of all seven parthenogenetic species of rock lizards, genus Darevskia, as well as their putative sexual parental populations, using double digest RAD-sequencing genomic markers. Taking advantage of the conserved homology of the ZW/ZZ sex chromosomes among lacertid lizards, we aligned our short sequence reads to a reference Z chromosome assembly of the common wall lizard Podarcis muralis. This provided unique insight into the origin of all-female hybrid populations, which inherited their single Z chromosome exclusively from a paternal ancestor. The mapped Z-linked loci were used to construct a robust time-calibrated phylogeny. In each parent–offspring species pair, the geographically nearest population of the paternal species was identified as the most likely ancestor of the respective parthenogen, mirroring the trend observed previously on the maternal side in mitochondrial DNA. The estimated splits between the sampled paternal sexual ancestors and their daughter species occurred much earlier than suggested previously and during two narrow time periods: (1) the parthenogenetic Darevskia armeniaca, D. dahli, D. uzzelli and D. rostombekowi dated back to ~0.5 or ~0.9 Mya, depending on the calibration point used, while (2) D. bendimahiensis, D. sapphirina and D. unisexualis appear to have diverged ~1 or ~2 Mya.
Bi-allelic variants inCHKAcause a neurodevelopmental disorder with epilepsy and microcephaly
Authors: Klöckner Chiara , Fernández-Murray J Pedro , Tavasoli Mahtab , Sticht Heinrich , Stoltenburg-Didinger Gisela , Scholle Leila Motlagh , Bakhtiari Somayeh , Kruer Michael C , Darvish Hossein , Firouzabadi Saghar Ghasemi , Pagnozzi Alex , Shukla Anju , Girisha Katta Mohan , Narayanan Dhanya Lakshmi , Kaur Parneet , Maroofian Reza , Zaki Maha S , Noureldeen Mahmoud M , Merkenschlager Andreas , Gburek-Augustat Janina , Cali Elisa , Banu Selina , Nahar Kamrun , Efthymiou Stephanie , Houlden Henry , Jamra Rami Abou , Williams Jason , McMaster Christopher R , Platzer Konrad 
Published: February 2022

AbstractThe Kennedy pathways catalyse the de novo synthesis of phosphatidylcholine and phosphatidylethanolamine, the most abundant components of eukaryotic cell membranes. In recent years, these pathways have moved into clinical focus because four of ten genes involved have been associated with a range of autosomal recessive rare diseases such as a neurodevelopmental disorder with muscular dystrophy (CHKB), bone abnormalities and cone-rod dystrophy (PCYT1A) and spastic paraplegia (PCYT2, SELENOI).We identified six individuals from five families with bi-allelic variants in CHKA presenting with severe global developmental delay, epilepsy, movement disorders and microcephaly. Using structural molecular modelling and functional testing of the variants in a cell-based Saccharomyces cerevisiae model, we determined that these variants reduce the enzymatic activity of CHKA and confer a significant impairment of the first enzymatic step of the Kennedy pathway.In summary, we present CHKA as a novel autosomal recessive gene for a neurodevelopmental disorder with epilepsy and microcephaly.