bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emergency care for patients with embolism of the aorta and main limb arteries in St. Petersburg: an analysis of 3498 cases over 50 years
Authors: Mel'nikov M. V. , Apresyan A. Yu. , Sotnikov A. V. , Kozhevnikov D. S. , Papava G. D. 
Published: January 2022

The Objective was to study our treatment experience for the past 50 years of patients with acute embolism of the aorta and main arteries of the limbs (EAMAL).Methods and materials. We analyzed our treatment experience of 3498 patients with EAMAL over the past 50 years, from 1971 to 2020. All patients were treated at a single department. It was one of the first vascular surgery departments established in St. Petersburg. All patients were admitted to our clinic in an emergency way, all of them received urgent angiosurgical care.Results. 3091 (88.4 %) patients were operated on, in 2950 (95.4 %) cases the primary operation was revascularization (embolectomy), in 141 (4.6 %) – limb amputation. 2725 (77.9 %) patients were discharged from the hospital with a saved limb, another 160 (4.6 %) – after limb amputation, 614 (17.5 %) died. According to our findings, it was demonstrated that in recent decades there became significant changes in the ethiology of arterial embolism. Nowadays, 92.2 % of patients with EAMAL have atrial fibrillation as an independent disease or as a complication of another pathology. Over the past decades, the incidence of rheumatic heart disease as a direct cause of embolism has decreased by 8 times. Changes in the structure of embologenic diseases are associated primarily with an increase in the proportion of elderly and senile people suffering from severe concomitant diseases. In recent decades, there has been an increase in the number of patients with embolism of the distally located arteries, mainly of the brachial and popliteal arteries, and a decrease in the rate of embolism of the large arterial vessels – the aorta and iliac arteries. Modern approaches have made it possible to optimize treatment, stick to more aggressive tactics, improve surgical techniques, and thereby reduce the overall and postoperative mortality rate by more than 2 times, which is currently 9 % and 7.5 % respectively.Conclusion. Despite modern advances in vascular surgery, EAMAL remains the actual and complex problem of the health care system of St. Petersburg for the past 50 years.
Solid-pseudopapillary neoplasia of the pancreas (analysis of three cases)
Authors: Durleshter V. M. , Heinrich S. R. , Kirakosyan D. S. 
Published: January 2022

The objective was to improve the early diagnosis efficiency of large pseudopapillary tumor of pancreas through the demonstration and analysis of three clinical cases.Methods and materials. In this work, the observation period was two years, in which three cases were diagnosed and treated a large number of pseudopapillary tumors.Results. With sufficient information on the characteristics of this disease, over the past 5 years we have had an opportunity to determine a diagnosis in two patients before the tissue examination.Conclusion. The age of patients, clinical manifestations, tumor size and the age of tumor patients are not reliable criteria for predicting the possibility of malignant tumors. Performing the operation in compliance with the principles of radicalism provide the best opportunity for recovery and reduces the early incidence of postoperative complications.
«МУСИМО СКАЗАТИ ЩИРО І ТВЕРДО: УКРАЇНА – СЕ СЕЛЯНСЬКА КРАЇНА»: АГРАРИСТСЬКИЙ ДИСКУРС ЕМІГРАЦІЙНОЇ ПУБЛІЦИСТИКИ М. ГРУШЕВСЬКОГО
Authors: Тельвак Вікторія , Корновенко Сергій 
Published: January 2022

Анотація. Мета дослідження полягає у всебічному осмисленні аграристського дискурсу еміграційної публіцистики М. Грушевського. Методологічне підґрунтя становить міждисциплінарний підхід. Особливий акцент зроблено на структурно-функціональному системному аналізі історіографічних фактів та методі критичного аналізу документального матеріалу. Наукова новизна статті полягає у спробі комплексного аналізу селянознавчих сюжетів публіцистики М. Грушевського 1919–1923 рр. Висновки. Підсумовуючи селянознавчі сюжети еміграційної публіцистики М. Грушевського, насамперед вкажемо на ті головні завдання, що стояли перед автором. По-перше, йшлося про потребу зміщення акцентів у тогочасній революційній риториці з пролетаріату на селянство, як домінуючий соціальний прошарок не лише в Україні, але й у низці інших аграрних держав Центрально-Східної Європи. Таке переакцентування мало на меті якщо не зупинити, то принаймні скоригувати той соціальний експеримент, що його заповідали більшовики. По-друге, необхідною була нова дорожна карта для української інтелігенції, котра в умовах пореволюційної зневіри втратила ідейні орієнтири, зосередившись на небезпечному для нації взаємопоборюванні. По-третє, відчутним виявився брак соціального оптимізму, що його історик намагався повернути, створюючи ідеалізований образ нового українського села. На жаль, радянофільська риторика селянознавчих роздумів М. Грушевського відштовхнула від них більшість представників української інтелігенції у вільному світі. Більшовики ж, попри сподівання вченого, проігнорували його застереження, зробивши з них ефективний інструмент для розколу революційного українства. Незважаючи на це, аграристська публіцистика М. Грушевського як важлива пам’ятка доби Визвольних змагань дала поштовх багатьом соціально-філософським дискусіям в українській діаспорі повоєнного часу.
Resiliensi Anak Jalanan yang Bersekolah di Rumah Singgah Diponegoro Surabaya
Authors: Sakwa Sakwa 
Published: January 2022

This study aims to describe the causes of decreased resilience of street kids and also to describe the factors that make children classified as having resilience or not. The approach used in this research is a qualitative approach with a case study design. The subjects in this study were street kids who to school at the Diponegoro Halfway House. Â Â Â Â Â Â Â Â Â Â Â Collecting data using interviews, observation, and documentation. From the results of the research conducted, it was found that the resilience of the four research subjects. Subjects had the ability of seven aspects of resilience with different strengths. Economic conditions and parental affection are several reasons why children take to the streets. At their age, who should be used to study in school, it is still a big task for educators. Not all street children who go to school have good resilience abilities, as the results of this study. The results showed that in general the street kids at Diponegoro Halfway House had good abilities and there was one subject who was not resilient. The different in strength is due to family background, the origin, of the child taking to different paths and associations at school. Â Keywords : resilience, street kids.
A practical case: features of the autoimmune insulin syndrome diagnosis
Authors: Zykova N. A. , Ignashina E. V. , Li E. D. , Kugryshev V. V. 
Published: January 2022

Autoimmune Insulin syndrome (AIS), also named Hirata disease, is a rare condition characterized by hypoglycemic episodes due to the presence of high titers of insulin autoantibodies (IAA). AIS is a form of immune-mediated hypoglycemia, which develops when a triggering factor (medication or a viral infection) acts on an underlying predisposing genetic background. The diagnosis of IAS is challenging, requiring a careful workup aimed at excluding other causes of hyperinsulinemic hypoglucemia. The article presents a case of Hirata disease diagnosing of a patient of the therapy department of the Multidisciplinary Medical Center of the Bank of Russia.Purpose: Determining of the features of the diagnosis of Autoimmune Insulin syndrome (Hirata disease)Materials and methods: the article presents a clinical case of the diagnosis of Autoimmune insulin syndrome (Hirata disease), focuses on the diagnostic signiﬁcance of laboratory tests. The article is intended for general practitioners, endocrinologists, gastroenterologists.
Features of diagnosis and treatment of acute and chronic pancreatitis with primary hyperparathyroidism
Authors: Stjazhkina S. N. , Kotova I. V. , Zarivchatsky M. F. , Chernysheva T. E. , Ledneva A. V. , Baltachev I. A. 
Published: January 2022

Aim: To identify a connection between acute and chronic pancreatitis and primary hyperparathyroidism on the base of clinical cases. To consider the features of the diagnosis and treatment of acute and chronic pancreatitis with primary hyperparathyroidism.Materials and methods: Over the past 10 years, there have been observed 3 cases of pancreatitis with primary hyperparathyroidism. Two patients were diagnosed with chronic pancreatitis, one patient was diagnosed with acute destructive pancreatitis. Patients were undergoing surgery, parathyroidectomy was performed.Results: Primary hyperparathyroidism is rarely associated with the occurrence of acute or chronic pancreatitis, but hypercalcemia plays an important role in the pathogenesis of these diseases. Pancreatitis usually occurs in the late stage of hyperparathyroidism, which explains the low prevalence of this association in developed countries, where primary hyperparathyroidism is diagnosed at an early stage of the disease.Conclusion: These clinical cases of radical surgical treatment of parathyroid adenoma associated with severe concomitant pathology testiﬁes to the eﬀectiveness of the surgical method in some cases. It is necessary to take into account severe concomitant pathology and diagnose and correct it in time.
Is it necessary to correct the intestinal microbiota disorders in chronic pancreatitis?
Authors: Ardatskaya M. D. , Maslovskii L. V. , Zverkov I. V. 
Published: January 2022

The frequency of intestinal microbiota disorders in patients with chronic pancreatitis (CP) is extremely high and can reach 97%. The bacterial overgrowth syndrome (SIBO) and the syndrome of increased epithelial permeability (SPEP), developing against the background of excretory insufficiency of the pancreas, affect the severity of the clinical picture of the disease, reduce the effectiveness of enzyme replacement therapy and generally contribute to the further progression of CP.The article presents a modern view on the mechanisms of the formation of SIBO and SPEP in CP. There is their aggravating effect on the course of the disease and the aggravation of disorders of the digestive and absorption processes that accompany them is shown and analyzed in the article.For decontamination of conditionally pathogenic and pathogenic ﬂora, increasing the number and metabolic activity of indigenous microﬂora in patients with CP, the use of a non-absorbable broad-spectrum antibiotic rifaximin is eﬀective. In order to restore the barrier function of the gastrointestinal mucosa, the drug of choice is rebamipid, a universal cytoprotector that affects all three levels of epithelial tissue protection (preepithelial, epithelial and subepithelial).Conclusion. CP is characterized by the complexity of its etiology and pathogenesis. Bacterial factors, in particular, SIBO and SPEP, play an essential role in the development of inﬂammatory changes in the pancreas. In the complex therapy of CP, it is advisable to take measures aimed at correcting disorders of the intestinal microbiota.
Crown disease with extrainterinal manifestations in the form of granulematous alveolitis
Authors: Barlamov P. N. , Tretyakova Yu. I. , Zhelobov V. G. , Khlynova O. V. 
Published: January 2022

Objective: To present a clinical description of the observation of a patient with Crohn’s disease (CD) with extraintestinal manifestations in the form of granulomatous alveolitis.Materials and Methods: A brief review of the literature on the current understanding of the prevalence and clinical manifestations of lung lesions in inﬂammatory bowel diseases (IBD) and CD, as well as a description of a patient with this pathology with the results of autopsy is presented.Results: The rare presence of granulomatous lung lesions in a patient with CD was proved.Conclusion: Diﬃculties in the diﬀerential diagnosis and treatment of CD lung lesions are shown. In particular, suspicion of tuberculous lesion, lung abscess creates potential risks of generalization of the process when using such therapeutic eﬀects as glucocorticosteroids, cytostatics, immunosuppressants, biological genetically engineered drugs and active surgical intervention. The authors hope that the described observation will alert doctors in terms of possible systemic pulmonary lesions in CD.
VEHICLE AIR CONDITIONER (VAC) CONTROL SYSTEM BASED ON PASSENGER COMFORT: A PROOF OF CONCEPT
Authors: Munahar Suroto , Purnomo Bagiyo Condro , Izzudin Muhammad , Setiyo Muji , Saudi Madihah Mohd 
Published: January 2022

The air conditioning system (AC) in passenger cars requires precise control to provide a comfortable and healthy driving. In an AC system with limited manual control, the driver has to repeatedly change the setting to improve comfort. This problem may be overcome by implementing an automatic control system to maintain cabin temperature and humidity to meet passenger's thermal comfort. Therefore, this paper presents the development of a laboratory-scale prototype air conditioning control system to regulate temperature, humidity and air circulation in the cabin. The experimental results show that the control system is able to control air temperature in the range of 21 °C to 23 °C and cabin air humidity between 40% to 60% in various simulated environmental conditions which indicate acceptance for comfort and health standards in the vehicle. In conclusion, this method can be applied to older vehicles with reasonable modifications.
ABSTRAK: Sistem penyejuk udara (AC) pada kenderaan penumpang memerlukan ketepatan kawalan bagi menyediakan keselesaan dan kesejahteraan pemanduan. Melalui sistem AC dengan kawalan manual terhad, pemandu perlu berulang kali mengubah penyesuaian latar bagi meningkatkan keselesaan. Masalah ini dapat diatasi dengan menerapkan sistem kawalan automatik bagi menjaga suhu dan kelembapan kabin agar memenuhi keselesaan suhu penumpang. Oleh itu, kajian ini merupakan pembangunan prototaip sistem kawalan AC skala laboratari bagi mengawal suhu, kelembapan dan peredaran udara dalam kabin. Hasil eksperimen menunjukkan sistem kawalan ini mampu mengendali suhu udara pada kitaran 21 °C hingga 23 °C dan kelembaban udara kabin antara 40% hingga 60% pada pelbagai keadaan persekitaran simulasi yang menunjukkan penerimaan standard keselesaan dan kesejahteraan kenderaan. Sebagai kesimpulan, cara ini dapat diaplikasi pada kenderaan lama dengan modifikasi bersesuaian.
COMPUTATIONLESS PALM-PRINT VERIFICATION USING WAVELET ORIENTED ZERO-CROSSING SIGNATURE
Authors: Chaudhari Jitendra , Mewada Hiren , Patel Amit , Mahant Keyur , Vala Alpesh 
Published: January 2022

Palmprints can be characterized by their texture and the patterns of that texture dominate in a vertical direction. Therefore, the energy of the coefficients in the transform domain is more concentrated in the vertical sideband. Using this idea, this paper proposes the characterization of the texture features of the palmprint using zero-crossing signatures based on the dyadic discrete wavelet transform (DWT) to effectively identify an individual. A zero-crossing signature of 4 x 256 was generated from the lower four resolution levels of dyadic DWT in the enrolment process and stored in the database to identify the person in recognition mode. Euclidean distance was determined to find the best fit for query palmprints zero-crossing signature from the dataset. The proposed algorithm was tested on the PolyU dataset containing 6000 multi-spectral images. The proposed algorithm achieved 96.27% accuracy with a lower recognition time of 0.76 seconds.
ABSTRAK: Pengesan Tapak Tangan boleh dikategorikan berdasarkan ciri-ciri tekstur dan corak pada tekstur yang didominasi pada garis tegak. Oleh itu, pekali tenaga di kawasan transformasi adalah lebih penuh pada jalur-sisi menegak. Berdasarkan idea ini, cadangan kajian ini adalah berdasarkan ciri-ciri tekstur pada tapak tangan dan tanda pengenalan sifar-silang melalui transformasi gelombang kecil diadik yang diskret (DWT) bagi mengecam individu. Pada mod pengecaman, tanda pengenalan sifar-silang 4 x 256 yang terhasil daripada tahap diadik resolusi empat terendah DWT digunakan dalam proses kemasukan dan simpanan di pangkalan data bagi mengenal pasti individu. Jarak Euklidan yang terhasil turut digunakan bagi memperoleh padanan tapak tangan paling sesuai melalui tanda pengenalan sifar-silang dari set data. Algoritma yang dicadangkan ini diuji pada set data PolyU yang mengandungi 6000 imej pelbagai-spektrum. Algoritma yang dicadangkan ini berjaya mencapai ketepatan sebanyak 96.27% dengan durasi pengecaman berkurang sebanyak 0.76 saat.
DETECTION OF TRAFFIC DENSITY WITH IMAGE PROCESSING USING PIN HOLE ALGORITHM
Authors: Irawanto Mochamad Aditya , Setianingsih Casi , Irawan Budhi 
Published: January 2022

The intelligent traffic monitors are devloped and became more interst in recent years. A detection system in the monitoring traffic system is proposed using different algorithms. Pin Hole Algorithm used to detect the car that passes the road (the studied area). A fixed camera mounted at predetermined point used with known height (of the camera), the intensity of the light, and the visibility of the camera. The classification process is important to know the traffic congestion status. The traffic congestion status will be sent to the server address already provided. In the congestion detection test results were obtained with an accuracy value of 85% using the 64x64 grid division and obtaining good detection results for susceptible light intensity values between 5430 and 41379 LUX with an accuracy value of between 60% and 90%.
ABSTRAK: Sejak beberapa tahun ini, sistem pengawasan trafik pintar telah dibina dan terus berkembang luas. Sistem pengesanan dalam sistem trafik pengawasan telah dicadangkan menggunakan pelbagai algoritma. Algoritma lubang pin digunakan bagi mengesan kereta yang melalui jalan (kawasan kajian). Kamera dipasang tetap pada titik tertentu iaitu dengan menyelaras ketinggian kamera, keamatan cahaya, dan kebolehlihatan kamera. Proses klasifikasi sangat penting bagi menentukan status kesesakan trafik. Status kesesakan trafik akan dihantar ke alamat pelayan yang telah disediakan. Nilai ketepatan ujian pengesanan kesesakan yang diperoleh adalah 85% iaitu menggunakan pembahagi grid 64x64 dan dapatan kajian menunjukkan pengesanan yang baik bagi nilai keamatan cahaya antara 5430 dan 41379 LUX dengan nilai ketepatan antara 60% dan 90%.
De novo Mutation Enables NOTCH3ECD Aggregation and Mitochondrial Dysfunction via Interactions with BAX and BCL-2
Authors: Liu Ruijie , Gao Chenhao , Shang Junkui , Sun Ruihua , Wang Wenjing , Li Wei , Gao Dandan , Huo Xuejing , Shi Yingying , Wang Yanliang , Wang Fengyu , Zhang Jiewen 
Published: January 2022

Background: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) caused by NOTCH3 mutations is the most common monogenic hereditary pattern of cerebral small vessel disease. The aggregation of the mutant NOTCH3 may play a cytotoxic role in CADASIL. However, the main mechanism of this process remains unclear. Objective: We aimed to investigate the possible pathogenesis of the mutant NOTCH3 in CADASIL. Methods: The clinical information of two pedigrees were collected and analyzed. Furthermore, we constructed cell lines corresponding to this mutation in vitro. The degradation of the extracellular domain of NOTCH3 (NOTCH3ECD) was analyzed by Cycloheximide Pulse-Chase Experiment. Flow cytometry and cell counting kit-8 assay were performed to observe the effects of the NOTCH3 mutation on mitochondrial function and apoptosis. Results: We confirmed a de novo heterozygous missense NOTCH3 mutation (c.1690G > A, p. A564T) in two pedigrees. In vitro, the NOTCH3ECD aggregation of A564T mutant may be related to their more difficult to degrade. The mitochondrial membrane potential was attenuated, and cell viability was significant decreased in NOTCH3ECD A564T group. Interestingly, BAX and cytochrome c were significantly increased, which are closely related to the mitochondrial-mediated pathway to apoptosis. Conclusion: In our study, the aggregation of NOTCH3ECD A564T mutation may be associated with more difficult degradation of the mutant, and the aggregation may produce toxic effects to induce apoptosis through the mitochondrial-mediated pathway. Therefore, we speculated that mitochondrial dysfunction may hopefully become a new breakthrough point to explain the pathogenesis of cysteine-sparing NOTCH3 mutations.
Igi Ńlá Wó: Ọlábìyí, Èèyàn Iyì Tí n Jẹ́ Yáì Sùn Kalẹ̀ Gbalaja!
Authors: Ọmọlọlá Báyọ̀ 
Published: January 2022

“Ọkùnrin lọ!
Ọkùnrin lọ!
Ò-bọ Sòkòtò f’ẹnu è sọlè ̣ ;̣
Ọkùnrin lọọọ!”
Igi dá nígbó;
Gbogbo igbó pa késekése!
Àgbà Òjọ̀ gbó ̣ n dolóògbé; ̣
Ilé ìmò dìtàn poo! ̣
Gbogbo àgbáyé ń ṣòfọ̀ ọmọ Odùduwà tó sílè ̣ wò ̣ !̣
Bíkú bá pa’jú ẹni dé,
Ẹgbé ẹni a sì máa wá rìrì kiri! ̣
Àwọn èèyàn tó màṣà tó mèdè, tó mẹni màṣà mèdè,
Gbogbo wọn ń dárò ẹni ire tó lọ!
Bí a bá pe’rí akọni,
À sì fidá lalè!̣
Àgbà ńlá ló fó!̣
Kete omi ta gbé rodò, kómi ó lè wálé subú yékẹ́ ,̣
Kasán já;
Agbagbáṣo kò rígbà ṣo o!
Ìlú Ṣábèẹ́ àt’orílè ̣ -èdè Bìnì nìkan kó ̣ ló pàdánù ẹni ire tó lọ; ̣
Gbogbo ayé ló ń mímí èdùn ló ̣ kàn nítòsí àti lókèèrè réré! ̣
Ibi téégún ṣeré dé,
Gbogbo wọn ni ò lè réégún mó!̣
Èkú nìkan ni gbogbo wa ń wò nílè ̣ !̣
Ẹyẹ sí, Ẹ
yẹ lọ;
Ìyé nìkan ló kù táaráyé ó máa wò l’é ̣ yìn ẹyẹ! ̣
A-gbéni-rìnrìn-àjò-dé’bi- ó sunwòn ti té ̣ rí gbaṣọ!
RESPON PERTUMBUHAN BIBIT KAKAO (Theobrama cacao L) PADA UKURAN WADAH TANAM POLYBAG YANG BERBEDA
Authors: Wahyudi  , Chairil Ezward  , A. Haitami  
Published: January 2022

Tanaman kakao (Theobrama cacao L) merupakan salah satu komoditas andalan perkebunan yang peranannya cukup penting bagi perekonomian nasional. Tingkat produksi tanaman kakao sangat ditentukan oleh baiknya perlakuan yang diberikan selama pertumbuhan dan perkembangannya. Penelitian ini memiliki tujuan untuk mengetahui respon pertumbuhan bibit kakao pada ukuran wadah tanam polybag yang berbeda. Penelitian ini berbentuk percobaan lapangan yang dilakukan di Desa Koto Kari, Kecamatan Kuantan Tengah Kabupaten Kuantan Singingi. Penelitian dilaksanakan selama 7 bulan menggunakan Rancangan Acak Kelompok Non Faktorial. Yaitu berbagai ukuran polybag terdiri 6 taraf perlakuan, masing-masing perlakuan diulang sebanyak 3 kelompok sehingga diperoleh 18 unit percobaan. Perlakuan yang diberikan adalah: Polybag 8 x 12 cm, Polybag 10 x 15 cm, Polybag 14 x 22 cm, Polybag 18 x 25 cm, Polybag 20 x 25 cm dan Polybag 25 x 40 cm. Hasil penelitian ini diuji secara statistik dengan uji F, kemudian bila berbeda nyata dilanjutkan dengan uji BNJ (Beda Nyata Jujur) pada taraf 5%. Parameter yang diamati adalah tinggi tanaman (cm), diameter batang (mm) dan bobot segar tanaman (gram). Berdasarkan hasil penelitian dapat disimpulkan bahwa perlakuan terbaik terdapat pada perlakuan wadah tanam Polybag 25 x 40 cm, tinggi tanaman 174,67 cm, diameter batang 2,00 mm, bobot segar tanaman 445,33 gram.
TO ASSESS THE INCIDENCE OF DVT AMONG PATIENTS OF LOWER LIMB SURGERIES /LOWER LIMB TRAUMA ADMITTED TO ST. STEPHEN?S HOSPITAL
Authors: Rai Ankur , Singh Shailendra Kumar , Gupta Rajendra Kumar 
Published: January 2022

Background: This study therefore aimed to assess the incidence of DVT among patients of lower limb surgeries /lower limb trauma admitted to St. Stephen?s hospital
Methods: The prospective study was conducted at St Stephen?s hospital from Jan 2019 to December 2019 for duration of 1 year, and 104 patients were part of the study.
Results: The overall prevalence of DVT in our study was found to be 2.8%. Out of 3 DVT cases 2 were found in males (3.4%) and 1 was a female (2.1%).
Conclusion: There is comparable incidence of DVT in our patients as compared to the incidence found in world literature. There is a need to institute DVT prophylaxis in patients undergoing major lower limb surgeries.
Keywords: DVT, Lower limb, Trauma