bluuebunny/crossref_metadata_2025_split huggingface dataset:
ІМПЛЕМЕНТАЦІЯ ЗАРУБІЖНОГО ДОСВІДУ СТРАТЕГІЧНОГО УПРАВЛІННЯ НА ВІТЧИЗНЯНИХ ПІДПРИЄМСТВАХ АГРАРНОГО СЕКТОРУ
Authors: Гречко А. В. , Джумакєєва Д. Д. 
Published: May 2022

Статтю присвячено аналізу особливостей впровадження стратегічного управління на вітчизняних аграрних підприємствах. Зокрема, досліджено підходи до визначення поняття «стратегія» та запропоновано власне визначення даного поняття. Авторами доведено, що головним завданням стратегії є об’єднання всіх видів діяльності підприємства, а також трудових ресурсів з метою отримання ряду переваг над конкурентами та досягнення високих результатів. В процесі дослідження було сформовано і економічно обґрунтовано думку про те, що розробка стратегії – це певний процес, основою якого є потенціал суб’єкта господарювання, а його основною характеристикою може бути виокремлення цілей та відповідних конкурентних переваг у довгостроковій перспективі, що коригуються завдяки вчасній адаптації до змін у зовнішньому середовищі за допомогою інноваційних технологій та ефективного антикризового управління. Крім цього, в процесі розробки обраного напряму дослідження, визначено особливості стратегічного управління аграрним підприємством та проаналізовано фактори, що перешкоджають прискореному розвитку галузі. Виявлено, що у провідних країнах із найбільш розвиненим агросектором значну роль відіграють транснаціональні компанії, і відповідно, сформовано рейтинг найбільших аграрних компаній світу, досліджено їх основні стратегічні напрямки розвитку. Проаналізовано фінансові результати до оподаткування за видами економічної діяльності за останні десять років і частку експорту за видами сільської продукції. З’ясовано, що найбільший експорт аграрної продукції становлять продукти рослинного походження, а головним імпортером української сільськогосподарської продукції є Китай. Розглянуто чинники, що впливають на вибір стратегії розвитку для аграрного підприємства. Також, автором доведено, що наявність стратегії не завжди означає її успішну реалізацію, що зокрема може бути спричинено наступним: невідповідність організаційної структури та обраної стратегії; непорозуміння серед керівників компанії; відсутність системи колективного прийняття рішень; нерішучість керівництва стосовно нових змін; відсутність достатньої кваліфікації та досвіду керівництва у сфері стратегічного управління; невідповідність рекламних замовлень сезонним коливанням їх реалізації; великий обсяг витрат тощо. Запропоновано імплементацію іноземних стратегій на вітчизняному ринку та принципи стратегічного розвитку аграрного сектору України. Розроблено етапи формування стратегії аграрного підприємства та обґрунтовано доцільність їх реалізації на вітчизняному ринку.
An assessment of the cheese product’s nutrient profile in implementation the new resource-saving technological solutions
Authors: Korotkova A. A. , Khramova V. N. , Bozhkova S. E. , Kartushina Y. N. 
Published: May 2022

In the сurrent conditions the cheese industry development is determining by perspective trends: medical and social – expansion the products range with dietary properties and reduced a calorie content, technological – mastering а new moulding methods for the production of complex and combined cheese products, economic – reduction of a milk consumption rates due to involvement secondary raw materials, ecological – minimizing the carbon footprint of cheese factories by reducing whey’s discharges. The patented method for producing the combined soft cheese product offers a set of resource-saving technological solutions for introducing into the cheese head an agarised jelly "filling" based on return salty whey with the spicy plant components addition. The original mold design forms a through hole in the center of the cheese head and provides the cheese part to the "filling" in а ratio as 4 : 1. The proposed method of the using salty sub-raw whey in soft cheese’s production is justified from the point of view the adequacy level its macro- and micronutrient composition to physiological requirements in food nutrients and energy. The new cheese product with a jelly "filling" contains 14.5% protein and 15.3% fat, that makes up for 17% of the requirements for adult. The product has a reduced calorie content to 208 kcal with a significant 28% energy contribution by the protein component, that gives it dietary properties. The cheese product’s provision by essential amino acids reaches 90% of the requirement in phenylalanine and tyrosine, 87% in lysine, 74% in isoleucine and leucine. The fatty acid profile is characterized by favorable a relative content values of linolenic and oleic acids. Low-molecular volatile fatty acids form the taste and aroma of cheese product without ripening. Its vitamin composition has functional availability for vitamins A - 40%, K - 31%, group B and PP - 15-20% of the requirement. The technological solutions for making of the cheese product with the "filling" maintain a functionality its nutrient profile, contribute to saving up to 20% of milk and increase the environmental friendliness of production.
Technology for obtaining a deposited catalyst based on an aluminosilicate matrix modified with europium oxide
Authors: Kuznetsova I. V. , Sugatov D. S. , Gryzlova V. I. 
Published: May 2022

The number of cars used worldwide is constantly growing. In this regard, the problem of combating atmospheric pollutants - exhaust gases of internal combustion engines is of particular relevance. Over the years, automakers have made many improvements to car engine design and fuel systems to meet pollution limits. One of the best solutions to this problem is the use of a so-called catalytic converter (converter) or simply a catalyst with a high content of noble metals, the main function of which is the simultaneous oxidation of unburned hydrocarbons and CO, as well as the reduction of nitrogen oxides. It was found that the addition of rare earth metals to Pd, Pt catalysts improves their properties and reduces the proportion of noble metals in the composition of catalysts. The paper presents the results of a study of complexation in the Eu3+-ligand system, where the ligand is an organic acid, by photocolorimetric and potentiometric methods. In the Eu3+-gallic acid system, a stable complex of the composition MeLnx – 1:2 is formed. In the Eu3+- oxalic acid system, a stable complex of the composition MeLnx – 1:1 is formed. In the Eu3+-valine system, a stable complex of the composition MeLnx – 1:2 is formed. A new technique for obtaining complex compounds is shown, consisting in adding hydrogen peroxide H2O2 to a solution containing solutions of Eu3+ salt and organic acid in an aqueous-alcoholic medium to block the reduction of Eu3+→Eu2+. A technology for obtaining a automotive catalyst has been developed, consisting of successive stages: obtaining complex compounds, applying the obtained complex compounds to ceramic block matrices, drying, applying platinum (palladium) acid, calcination. The presence of the Eu3+ ion in the ceramic matrix is proved by the method of elemental analysis. The technology can be applied to solve the problem of environmental pollution, such pollutants as exhaust gases of cars containing a lot of harmful substances in their composition.
New horizons of cooperation
Authors: Kolesnikov Andrey Vitalievich , Malinetskii Georgii Gennadyevich , Sirenko Svetlana Nikolaevna 
Published: May 2022

We present an analysis of reports, round table discussions, ap-proaches presented at the V International Conference “Designing the Future and Horizons of Digital Reality”. The focus of the conference participants was the analysis of the results, risks and prospects for the development of the com-puter reality of the world and the Belarus-Russia Union State from the position of an interdisciplinary synthesis of knowledge at the intersection of philosophy, mathematics, computer science, sociology and a number of other disciplines. At one time, the Nobel Prize laureate academician Zh.I. Alferov said that it is in Russia and Belarus that the potential in the field of information and tele-communication (IT) technologies is greatest among the post-Soviet countries. And it is these technologies that should become the basis of our scientific and technical breakthrough. This foresight is the leitmotif of this conference. In one of his speeches, the President of the Russian Federation said that those who have mastered artificial intelligence will become the rulers of the world, and that it is very important that they do not turn out to be separate groups of people or countries. Artificial intelligence has become one of the central topics and the subject of lively discussions at the conference. One reality ends and another begins. Its risks, threats and opportunities were the most important and interesting elements in the approaches put forward in this forum.
Development of an integrated and comprehensive clinical trial process management system
Authors: SHEN Liang , ZHAI You , PAN AXiang , ZHAO Qingwei , ZHOU Min , Liu Jian 
Published: May 2022

Abstract
Background: The process of initiating and completing clinical drug trials in hospital settings is highly complex, with numerous institutional, technical, and record-keeping barriers. In this study, we independently developed an integrated clinical trial management system (CTMS) designed to comprehensively optimize the process management of clinical trials. The CTMS includes system development methods, efficient integration with external business systems, terminology, and standardization protocols, as well as data security and privacy protection. Methods: The development process proceeded through four stages, including demand analysis and problem collection, system design, system development and testing, system trial operation, and training the whole hospital to operate the system. The integrated CTMS comprises three modules: project approval and review management, clinical trial operations management, and background management modules. These are divided into seven subsystems and 59 internal processes, realizing all the functions necessary to comprehensively perform the process management of clinical trials. Efficient data integration is realized through extract-transform-load, message queue, and remote procedure call services with external systems such as HIS, LIS, EMR, and CDR. Data security is ensured by adopting corresponding policies for data storage and data access. Privacy protection complies with laws and regulations and de-identifies sensitive patient information. Results: The integrated CTMS was successfully developed in September 2015 and updated to version V4.2.5 in March 2021. During this period, 1388 study projects were accepted, 43,051 electronic data stored, and 12,144 subjects recruited in the First Affiliated Hospital, Zhejiang University School of Medicine.Conclusion: The developed integrated CTMS realizes the data management of the entire clinical trials process, providing basic conditions for the efficient, high-quality, and standardized operation of clinical trials.
Combating COVID-19 Infodemic: A Step Towards Building Public Trust
Authors: Hassan Radwa Ibrahim Ali , El-Salamony Omaima Kamel , Abdel-Aziz Shaimaa Baher , Fathelbab Mohamed , Sabry Hend Aly 
Published: May 2022

Abstract

Background: The spread of misinformation about different health issues, has become a growing threat nowadays. The process of identifying credible information became a real problem of high urgency. It took a new dimension with the creation of numerous web platforms and ubiquity of internet coverage. During the current pandemic of COVID-19, misinformation is not the only challenge, but infodemic is another serious consequence of the growing digitization. Infodemic is defined as an excessive amount of information about a problem that is typically unreliable, false or misleading, spreads rapidly, and makes a solution more difficult to achieve. This causes anxiety and mistrust in health authorities, leading to decrease capacities for decision-making and undermining public responses, especially during disease outbreaks or pandemics. Aim: The current study was designed to evaluate the effect of implementing a digital intervention training module, to educate participants about choosing credible online health information, according to quality standards and protocols. Methods: This is a quasi-experimental study with pre/post-assessment comparisons. It took place between October 2019 and October 2020 with the recruitment of a group of 480 medical students, from 1st , 2nd and 3rd academic years, at the Faculty of Medicine. They were assigned to an intervention and a control group. The intervention group attended the digital health module, which was conducted online with both its theoretical and practical components. Participants responded to pre and post online questionnaire through google forms, in addition to a post-intervention assessment. Results: Results showed post-assessment significant improvements in all items related to seeking online health information and the ability to check the credibility of such information, among the intervention group in comparison to the control group with p-value< 0.05. Conclusion: The infodemic caused by COVID- 19 pandemic, with all its associated psychological pressure and panic due to misinformation, made it really crucial to disseminate awareness about credible digital information sources. Targeted digital health interventions about online health information quality and credibility, are highly promising, due to the safe outreach and accessibility without any physical contacting, especially during the pandemic time.
NEPSscaling: Plausible Value Estimation for Competence Tests Administered in the German National Educational Panel Study
Authors: Scharl Anna , Zink Eva 
Published: May 2022

Abstract
Educational large-scale assessments (LSAs) often provide plausible values for the administered competence tests to facilitate the estimation of population effects. This requires the specification of a background model that is appropriate for the specific research question. Because the German National Educational Panel Study (NEPS) is an ongoing longitudinal LSA, the range of potential research questions and, thus, the number of potential background variables for the plausible value estimation grow with each new assessment wave. To facilitate the estimation of plausible values for data users of the NEPS, the R package NEPS scaling allows their estimation following the scaling standards in the NEPS without requiring in-depth psychometric expertise in item response theory. The package only requires the user to prepare the data for the background model. Then, the appropriate item response model including the linking approach adopted for the NEPS is automatically selected, while a nested multiple imputation scheme handles missing values in the background data. For novice users, a graphical interface is provided that does not require knowledge of the R language. Thus, NEPS scaling can be used to estimate cross-sectional and longitudinally linked plausible values for all major competence assessments in the NEPS.
Genetic diversity and population structure of Triticum araraticum and Triticum timopheevii
Authors: Peng Ting , Jiang Xiaomei , Wang Dinghao , Zhang Minghu , Liu Xin , Hao Ming , Li Wei , Liu Dengcai , Jiang Bo , Huang Lin , Ning Shunzong , Yuan Zhongwei , Wu Bihua , Yan Zehong , Chen Xuejiao , Chen Xue , Zhang Lianquan 
Published: May 2022

Abstract
Genetic diversity is an important resource to improve new wheat cultivars in the breeding program. In this study, fluorescence in situ hybridization (FISH) and genotyping by sequencing (GBS) were used to evaluate the genetic diversity and population structure of the timopheevii group (AtAtGG, 2n = 4x = 28) including 15 Triticum timopheevii Zhuk. accessions and 35 Triticum araraticum Jakubz. accessions. FISH analysis showed that there were 14 and 19 FISH signal variations in the At and G genome of T. araraticum, respectively. But there were only two signal variations in the G genome of T. timopheevii. In this study, 190,402 SNP markers were obtained from GBS, in which the lowest and highest frequencies of SNPs were found in the G and At genomes, respectively. Genetic diversity analysis of the 50 accessions indicated that the mean GD and PIC were 0.30 and 0.26, with the ranges of 0.1–0.5 and 0.1–0.4, respectively. The highest and lowest numbers of SNPs identified on the chromosomes 4G and 2At were 7,748 and 17,527, respectively. Structure and cluster analyses divided 50 accessions into two subpopulations (POP1 and POP2). POP1 mainly consisted of most Triticum araraticum accessions, and POP2 comprised all accessions of Triticum timopheevii and one Triticum araraticum accession AS273. In addition, the genetic variance showed that genetic variation was greater within populations (97%) than between populations (3%). POP1 and POP2 had high levels of genetic diversity and POP1 showed higher genetic diversity. The POP1 (I = 0.53, He = 0.35, uh = 0.35) showed higher genetic diversity than POP2. The present results provided important information for the improvement of cultivated durum and hexaploid wheat production in future breeding programs of China and other countries.
Acute kidney injury related to Cordyceps militaris: A case series
Authors: Tangkiatkumjai Mayuree , Chaiyarak Supatyada , Sripr Suwannee , Lumboot Ueamporn , Absuwan Warayut , Changsirikulchai Siribha 
Published: May 2022

Abstract
BackgroundCordyceps sinensis is an ancient traditional Chinese medicine, known as caterpillar fungus, that is one of the most commonly used ingredients to treat people with chronic kidney disease or to facilitate post-kidney transplant health. Unfortunately, due to unavailability and heavy metal contamination, Cordyceps militaris has been substituted instead and incorporated into over 400 dietary supplements sold in Thailand. This is the first case series report to inform health care providers about nephrotoxicity related to C. militaris supplements.Case presentationEleven patients had acute kidney injury (AKI) related to dietary supplements of C. militaris, which mainly contained cordycepin. Most of these patients from central Thailand (2018–2021) were elderly and five patients had chronic kidney disease stage 3 to 5. Two patients developed AKI requiring dialysis. The causality of AKI related to C. militaris was assessed by the modified Naranjo algorithm and a probable relationship was found between C. militaris and AKI (range from 6–8 scores). Two potential mechanisms of nephrotoxicity from C. militaris were cyclooxygenase-2 inhibition and direct toxicity at kidney tubule.ConclusionsPatients with kidney insufficiency and elderly should avoid using health products containing C. militaris until further clinical research determines such supplementation safe and effective.
Accelerated tibia fracture healing in traumatic brain injury in accordance with increased hematoma formation
Authors: Shim Dong Woo , Hong Hyunjoo , Cho Kwang-Chun , Kim Se Hwa , Lee Jin Woo , Sung Seung-Yong 
Published: May 2022

Abstract
Background: Traumatic brain injury (TBI) has been known to accelerate bone healing. Many cells and molecules have been investigated but the exact mechanism is still unknown. The neuroinflammatory state of TBI has been reported recently. We aimed to investigate the effect of TBI on fracture healing in patients with tibia fractures and assess whether the factors associated with hematoma formation changed more significantly in the laboratory tests in the fractures accompanied with TBI.Methods: We retrospectively investigated patients who were surgically treated for tibia fractures and who showed secondary bone healing. Patients with and without TBI were divided for comparative analyses. Radiological parameters were time to callus formation and the largest callus ratio during follow-up. Preoperative levels of complete blood count and chemical battery on admission were measured in all patients. Subgroup division regarding age, gender, open fracture, concomitant fracture and severity of TBI were compared.Results: We included 48 patients with a mean age of 44.9 (range, 17 – 78), of whom 35 patients (72.9%) were male. There were 12 patients with TBI (Group 1) and 36 patients without TBI (Group 2). Group 1 showed shorter time to callus formation (P < 0.001), thicker callus ratio (P = 0.015), leukocytosis and lymphocytosis (P ≤ 0.028), and lower red blood cell counts (RBCs), hemoglobin, and hematocrit (P < 0.001). Aging and severity of TBI were correlated with time to callus formation and callus ratio (P ≤ 0.003) while gender, open fracture, and concomitant fracture were unremarkable.Conclusion: Tibia fractures with TBI showed accelerated bone healing and superior measurements associated with hematoma formation (lymphocytes, RBCs, hemoglobin, hematocrit). Promoted fracture healing in TBI was correlated with the enhanced proinflammatory state.Level of evidence: III, case control study
Natural extracts from Eugenia brasiliensis Lam leaves to improve the shelf-life of fresh tomatoes
Authors: Igarashi-Mafra Luciana , de Souza Pércia Graczyk , Toci Aline , Amaral Wanderlei do , Mafra Marcos R. , Farias Fabiane Oliveira 
Published: May 2022

Abstract
In this work, hydroalcoholic extracts were obtained from leaves of Eugenia brasiliensis to be evaluated for the content of bioactive compounds and applied to fresh tomatoes for preservation. Analyzes of total phenolics, flavonoids, antioxidant and antibacterial activity, and toxicity were performed. Tomatoes were treated with the extracts by immersion in an aqueous solution at 200, 600, and 1000 mg/L and evaluated for 28 days for total soluble solids, titratable acidity, maturation index ascorbic acid content, weight loss, and visual test. The presence of gallic acid, rutin, and quercetin was identified in all extracts. The extracts obtained by water and ethanol at 25% e 50% showed better results regarding phenolic compounds; antioxidant and antimicrobial activity. However, the 25 and 50% ethanol extracts were the only ones that showed toxicity. The treatments proposed for the conservation of tomatoes, in concentrations superior to 600 mg/L, showed promising results, mainly in the protection of the fruits regarding the loss of water and, consequently, visual depreciation due to the appearance of wrinkles. Thus, most proposed treatments demonstrated viability because of conserving organoleptic properties of fresh tomatoes.