bluuebunny/crossref_metadata_2025_split huggingface dataset:
Overlaping Syndromes: Kawasaki-Like Disease in Pediatric Multisystem Inflammatory Syndrome vs Atypical Kawasaki Disease. British or American? One Case, Many Possibilities
Authors: Voicu Cristiana , Grigore Cosmin , Stefan Dan , Filip Cristina , Duica Gabriela , Nicolae Georgiana , Balgradean Mihaela , Nicolescu Alin , Cinteza Eliza 
Published: March 2022

Abstract
Kawasaki disease is a challenging diagnosis even in typical forms of presentation. The features are represented by long lasting fever, specific mucocutaneous signs and coronary artery dilations as expression of medium artery vasculitis of unknown origin. Kawasaki-like disease emerged as a variant of pediatric multisystem inflammatory syndrome (PMIS) associated with COVID-19 infection. A 1 year 9-month-old boy who presented with fever, semi-consistent stools, vomiting, facial edema and hepatomegaly was transferred in our hospital with suspicion of myocarditis due to the clinical presentation, inflammatory markers and systolic dysfunction. In a few days after presentation, also, dilation of the coronary artery appeared while the child had persistent constant symptomatology. Gradually, a pediatric multisystem inflammatory syndrome (PMIS) developed, but without positive markers of COVID-19 infection, which remained negative (both antigen and antibodies). So, in front of all elements of PMIS except exposure to SARS-CoV-2, we concluded for an atypical Kawasaki disease with elements of PMIS. But the debate between the elaborated criteria British and American for PMIS are circling around the demonstration of the infection, past or present, making some cases difficult to diagnose.
In this high affluence of Kawasaki-like disease, with intricated elements of myocarditis and multisystem inflammatory syndrome it is more and more difficult to establish a clear diagnosis. While the diagnosis looks complex, the curative treatment goes in the same direction – immunoglobulin, immunosuppressive treatment, inotropic and antiaggregant or anticoagulant treatment.
A construção das masculinidades dos trabalhadores das minas de carvão em Santa Catarina (1940-1970)
Authors: Mandelli Bruno 
Published: March 2022

Este artigo abordará a construção das masculinidades e da cultura de virilidade na categoria dos mineiros de carvão no Sul do Brasil, na região carbonífera de Santa Catarina entre as décadas de 1940 a 1970. A partir dos referenciais de masculinidade e masculinidade hegemônica, primeiro será analisado o mineiro em seu ambiente de trabalho, as minas de carvão, por ser o espaço onde mais tempo passavam. Em seguida, percorreremos outros espaços de sociabilidades masculinas, como os bares, as zonas de prostituição e as rinhas de galo, para identificar outros locais onde tais práticas eram reproduzidas socialmente. Portanto, a partir de aspectos de uma cultura de classe, será discutido como a construção da honra masculina e de suas práticas sociais estão imbricadas na formação da masculinidade dos mineiros como um elemento central de suas vidas.
Use of closed chain exercises, eccentric exercises, and proprioceptive muscle facilitation to prevent elbow injuries in climbers: a randomized control trial
Authors: Kozin Serhii , Kozina Zhanneta , Cretu Marian , Boychuk Yuriy , Safronov Danylo , Korobeinik Vitalii , Chernozub Andrii 
Published: March 2022

IntroductionTo determine the influence of exercises in a closed kinematic chain, exercises in eccentric mode in combination with proprioceptive muscle facilitation on the level of injuries and technical skill of amateur climbers.MethodsThe participants in this study were 84 male amateur rock climbers, aged 18–19; 40 athletes were in the Intervention Group and 44 athletes were in the Control Group. In the Intervention Group, a developed injury prevention program was used. The program included the use of neuromuscular training. Exercises for proprioceptive muscle facilitation were also used. We determined the Incidence rate ratio and confidence intervals and the reliability of the influence of the level of mastery of the technique on the number of injuries by the Cochran’s and Mantel-Haenszel methods.ResultsThe use of our program reduces the Incidence rate ratio in climbers for mild, moderate and severe elbow injuries; a significant decrease was found for moderate and severe injuries. There was also a significant improvement in the results of biomechanical analysis of climbing technique in athletes in the Intervention Group (<i>p</i> < 0.001). There was a high reliability of the influence of the level of mastery of the technique on the number of injuries (<i>p</i> < 0,001).ConclusionsThe use of exercises in a closed kinematic chain, exercises in eccentric mode in combination with proprioceptive muscle facilitation reduces the Incidence rate ratio of the shoulders and increases technical skill among amateur climbers.
Operation inﬂuence of the climate system on the speciﬁc energy consumption of M3 electric bus category
Authors: Malikov R. R. , Biksaleev R. Sh. , Karpukhin K. E. , Klimov A. V. 
Published: March 2022

Introduction(statement of the problem and relevance).At present, little attention is paid to the analysis of vehicle climate systems operation, though maintaining a comfortable temperature in the cabin under some conditions makes up the majority of energy costs. In some cases, lack of energy leads to the use of diesel heaters. In this respect, the assessment of the climate system impact on energy consumption is an urgent task of today.The main purposeof this article was to calculate and analyze the speciﬁc costs in various temperature conditions on the example of M3 passenger electric bus category.Methodology and research methods.In the article the methods to construct a mathematical model of the temperature effect on the air inside the vehicle using the heat balance equation were proposed. Also, a method of car traction balance was used to build a model of vehicle motion.Scientiﬁcnovelty and results.As a result of an electric bus motion modeling according to the OCB cycle, energy costs at temperatures from –40°С to +40°С have been determined. The highest energy consumption in winter was 2.63 kW·h/km at –40°C.Practicalsigniﬁcance.At the ﬁrst approximation the article allows to determine the speciﬁc costs for M3 passenger vehicle category, and basing on earlier developed methods, makes it also possible to build a mathematical model to determine the energy costs for any type of wheeled vehicle.
Analisis Kepuasan Pengguna Aplikasi Daily Apps Berbasis Web Di Internal Divisi Digital Marketing PT. Transcosmos Indonesia dengan Metode End-User Computing Satisfaction (EUCS)
Authors: Nimah Arini Islahul , Haryatmi Emy 
Published: March 2022

Website saat ini dimanfaatkan untuk hal manajemen internal, maupun untuk promosi ke pihak eksternal perusahaan, baik untuk mengumpulkan ataupun membagikan informasi kepada pengguna. Daily Apps adalah suatu aplikasi yang digunakan oleh karyawan Divisi Digital Marketing PT. Transcosmos Indonesia dengan tujuan merekam Daily Data, Project List, hingga menampilkan Individual Rates maupun Team / Group Rates. Masalahnya Daily Apps yang digunakan di internal divisi Digital Marketing belum pernah diulas sama sekali sehingga belum dapat diketahui kepuasan penggunanya. Tujuan penelitian ini adalah Menganalisis kuisioner kepuasan pengguna aplikasi Daily Apps menggunakan metode End User Computing Satisfaction (EUCS). Penelitian ini menggunakan metode kuantitatif, sedangkan teknik pengumpulan data menggunakan kuesioner dengan mengaplikasikan model End User Computing Satisfaction (EUCS), yang dianalisis menggunakan analisis factor. Kemudian disebarkan kepada 71 responden yang merupakan karyawan Divisi Digital Marketing PT. Transcosmos Indonesia. Hasil dari penelitian menunjukkan bahwa kepuasan pengguna berdasarkan analisis faktor yaitu pada Indikator content mempunyai pengaruh terbesar terhadap kepuasan pengguna Daily Apps di Divisi Digital Marketing PT. TCID, dengan nilai sebesar 2,908 atau > 1 maka menjadi faktor pertama, sedangkan pada indikator accuracy, timeliness,format, dan ease of use, didapatkan nilai < 1 maka dianggap faktor yang tidak mempengaruhi kepuasan pengguna.
The Game “Quiz Besemah” Sebagai Media Untuk Memperkenalkan Budaya Kota Pagar Alam
Authors: Rahmadi Lendy , Triawan Medi 
Published: March 2022

Pagar Alam City has great potential in the field of tourism, both natural and cultural tourism. Pagar Alam City is also known as one of the Besemah tribal areas with various cultural heritages. Game "Quiz Besemah" is a mobile quiz and educational game specially designed for learning the culture and traditions of the city of Pagar Alam. The development method used in this research is Game Development Life Cycle (GDLC) with six stages, namely Initiation Developer, Pre-Production, Production, Testing, Beta External Testing and Release Game. The game engine for developing game features will use the Unity application so that it can support various platforms such as web, windows, mac, android, iOS, Xbox, Playstation 3 and Wii. The game that was built consisted of 20 (twenty) questions randomly and divided into 4 (four) classifications, namely basic, easy, medium and difficult. This game is recommended and user friendly for children aged 8-13 years. Based on the results of testing the application that has been built, it can be concluded that the game can be used as a learning medium for the introduction of Besemah culture in Pagar Alam City
Analisis Kualitas Layanan Website Pada Universitas Terbuka Palembang Menggunakan Metode Webqual 4.0 Dan Importance Performance Analysis (IPA)
Authors: Mardalena Obi , Andryani Ria 
Published: March 2022

Website is a medium that is currently widely used as a tool to provide services and information. Palembang Open University is one of the universities that uses the website as a means to provide information related to academic activities to its students. To determine the quality of a website, it is necessary to analyze the measurement of website quality based on user perceptions. The purpose of this Analysis is used to determine the indicators that affect the quality of website services based on the instrument used from the webqual 4.0 method which consists of 3 variables, namely usability, information quality, and service interaction quality. Then the analytical technique used is importance performance Analysis (IPA) which will provide an overview of the indicators that need improvement or need to be maintained. The data collection technique in this study used a questionnaire with a research sample of 100 respondents. The results of the Analysis of the quality of website services at the Open University of Palembang have a suitability level of 99.99% or <100%. While the results of the average value of the gap (GAP) have a value of -0.01 which means that the quality of website performance has not fully met user expectations. Then the results of the Analysis of the IPA quadrant that need improvement because this quadrant has a low level of performance, so it can affect the level of interest of users to rely on these indicators, namely in the first priority quadrant which is indicator number 14 detailed information, indicator number 15 information in a format that according to indicator number 17 the website is safe from viruses.
Customer Engagement Analysis as Mediating the Influence on Social Media Marketing of Purchase Intentions on Skincare Avoskin
Authors: Perkasa Chreisna Wicaksono , Faritzal Adam 
Published: March 2022

This research aims to analyze customer engagement in mediating the influence of social media marketing on purchase intentions. The approach used in this study is quantitative; the population of this study is all users of Avoskin skincare products in Bandung. Data is analyzed by testing the validity, reliability, and inner model using smartPLS. The results showed a direct influence of social media marketing activities on purchase intentions in Avoskin skincare users in Bandung, and customer engagement can mediate the influence of social media marketing activities on purchase intentions.
Strategic Planning of Information Systems and Information Technology by applying the Tozer Methodology to The Lampung Betacom Pawnshop
Authors: Florentine Chelsea , Chernovita Hanna Prillysca 
Published: March 2022

Betacom is one of the pawnshops established since 2017, which is engaged in the service of distributing loan money to the public based on pawn law with electronic goods guarantees such as mobile phones, laptops, TVs, and so on. In carrying out its business processes, Betacom pawnshops have implemented information systems and information technology but are still not optimal, have not been integrated with each other and are not in line with the mission vision and business strategy of Betacom pawnshops. Therefore, proper strategic planning is needed. This strategic planning will be carried out using the Tozer method, to produce a strategic planning model of information systems that can support and improve the business processes of Betacom pawnshops. This research aims to improve the quality of business processes and SI / IT that can answer solutions to problems that occur. The output resulting from this research is in the form of recommendations for the results of strategic planning of information systems that can be used in the future.
The Ontology and Epistemology of Maqāṣidī-based Knowledge and Its Educational Implications
Authors: Moniem Aly Abdel 
Published: March 2022

Maqasid al-Shariah herein denotes the higher objectives of the Islamic Revelation that guide Muslim worldly and spiritual life. This article aims to extract these Maqasid from the Holy Qur’an and investigate their philosophical, theoretical and practical implications. Ontologically, Maqasid entails a systematic view of the universe that governs the relationship between the Creator and His creation, which in turn governs the natural, psychological and social environments. In this regard, Maqasid proposes an integrated network of relations between these environments, incorporating ʻibādah, ʻimārah, tazkiyah, khilāfah, and istikhdām maqaṣidī. Epistemologically, Maqasid implies a fact-based, systematic, developmental and purified base for the ontological theses suggested. Moreover, this research seeks to apply the Maqāṣidī-based thought educationally and methodically through the standards of competencies and content that are defined from its multifaceted paradigm based on its ontological and epistemological perspectives. The Maqāṣidī-based approach provides an alternative to the limitations found within the current educational systems and policies that hinder the application of the Maqasid revelation. Thus, this study proposes a multidimensional rationalization of the Maqāṣidī-based thought in education to achieve development and true success.
Clinical and laboratory features of the new coronavirus infection COVID-19 in patients with connective tissue dysplasia
Authors: Moskaleva Ju. N. , Khamanova Ju. B. , Kuznetsov P. L. , Galeev R. S. 
Published: March 2022

Introduction. Connective tissue is ubiquitous in the human body, hereditary connective tissue disorders affect several systems and organs, undifferentiated connective tissue dysplasia is often not diagnosed, proceeds under the guise of another pathology, and the pathogenetic basis of COVID-19 is a systemic disease associated with vascular inflammation and endothelial damage. The goal is to study the clinical and laboratory features of a new coronavirus infection in patients with connective tissue dysplasia.Materials and methods. The study included 117 patients diagnosed with a new coronavirus infection COVID-19 aged 35 to 65 years, hospitalized in an infectious diseases hospital City Clinical Hospital No. 40 in Ekaterinburg. The patients were divided into 2 groups: the main group (n=90) people with the stigmas of connective tissue dysplasia and the comparison group: (n=27) people without signs of connective tissue dysplasia. Inclusion criteria: the presence of stigma of connective tissue dysplasia, the presence of a confirmed infection with COVID-19 (PCR of nasopharyngeal and oropharyngeal swabs for SARS-CoV-2). Exclusion criteria: age over 65, comorbidities: diseases of the musculoskeletal system, chronic kidney disease, pregnancy, HIV infection, oncohematological and lymphoproliferative diseases.Results. The course of a new coronavirus infection against the background of connective tissue dysplasia is characterized by: 1) fever in 100% of patients; 2) damage to the lungs of more than 50% of the lung tissue with signs of respiratory failure in 63%; 3) a pronounced systemic inflammatory response syndrome, manifested by a significant increase in C-reactive protein and creatine phosphokinase.Discussion. An analysis of the results showed that one of the predictors of the severity of the course of COVID-19 infection may be the presence of connective tissue markers of dysplasia (odds ratio 7.4, 95% CI 2.6-21.3).Conclusion. The new coronavirus infection COVID-19 proceeds against the background of connective tissue dysplasia more severely with a pronounced intoxication syndrome with an early and longer manifestation of acute respiratory failure.
Nutritional approaches to correction of metabolic syndrome before abdominoplasty
Authors: Popov A. A. , Leonteva G. A. , Stolina E. A. , Airapetova E. L. , Bagrova E. N. , Fedotova L. V. , Akimova A. V. 
Published: March 2022

The aim of the study was to highlight modern approaches to the dietary correction of metabolic syndrome in patients who have decided to perform abdominoplasty. Materials and methods. The keywords driven search for scientific references was carried out in the PubMed, Google Scholar and elibrary.ru databases for the period from 2000 to 2020. 38 sources were selected from 159 received links. Results and Discussion. Current approaches to dietary therapy of obese patients who have decided to perform abdominoplasty, taking into account the comorbidity of patients, is provided. Particular attention is drawn to the subjects’ nutritional status periodical reassessment, the identification and comprehensive correction of carbohydrate and lipid metabolism disorders both at the stage of preoperative preparation and throughout subsequent life. The principles of calculating the daily caloric content and the nutrition planning are considered. A personalized interdisciplinary approach to patient management within the wide specialties spectrum (internist, endocrinologist, cardiologist, gastroenterologist, nutritionist, psychotherapist, plastic surgeon) cooperation and the application of digital technologies for remote life-long monitoring and counseling is discussed. Conclusion. A unified algorithm of actions of an interdisciplinary team of specialists, taking into account the personal characteristics and needs of patients, the possibilities of digital technologies, allows to reduce the risk of developing comorbid pathology, improve the results of abdominoplasty, the quality and life expectancy of the patient and ensure the best therapeutic and aesthetic result, as well as prevent relapses of weight gain during long-term follow-up of patients after abdominoplasty.
The dynamics of quality of life indicators in women against the background of personalized therapy of menopausal syndrome combined with perimenopausal melatonin deficiency syndrome
Authors: Mamontova A. G. , Usoltseva E. N. , Soloviev A. G. 
Published: March 2022

Introduction. Climacteric syndrome (CS) significantly reduces the quality of life (QOL) of peri— and postmenopausal women. Along with sex steroid deficiency in KS, there is a change in the synthesis of the epiphysis hormone melatonin (MT), which leads to the formation of perimenopausal melatonin deficiency syndrome (SPDM) (Patent 2019118500/14(035525) of 16.05.2020). The aim of the work was to evaluate clinical efficacy and QOL dynamics in women against the background of personalized treatment of CS in combination with SPDM. Methods and Materials. The study included 163 women. Groups 1, 2, 3 and 4 consisted of patients with CF and SPDM, control group 5 consisted of women with a normal course of the menopausal period and the absence of clinical manifestations of MT deficiency. After collecting medical history, determining the degree of CS severity with the help of the modified menopausal index (MMI) (H. Kuppermanetal. 1959, modified by E.V. Uvarova 1983), CS was assessed by the SF-36 general questionnaire and special women's health questionnaire (WHQ). The presence of MT deficiency was determined by the MT deficiency test-questionnaire and the WHQ scales. According to the «Stratification Algorithm for Women in the Menopausal Transition and Postmenopause with CS in Combination with SPDM for Selecting Differentiated Therapy» that we developed, Group 1 patients received MT monotherapy, Group 2 — synthetic gynestein, Group 3 — menopausal hormone therapy in combination with MT, and Group 4 — synthetic gynestein with MT for 5-6 months. The data were statistically processed using SPSSv13.0 software. The χ2 criterion was determined at baseline and the Wilcoxon test was used for dynamic follow-up. Results. Patients in groups 1, 2, 3, and 4 experienced relief of both the clinical manifestations of CS and SPDM and an increase in the physical and psychological components of QOL according to the SF-36 general questionnaire and the vast majority of the scales of the special WHQ questionnaire. Discussion. We hypothesized that the lack of complete efficacy of CS therapy in peri— and postmenopausal women is associated with the absence of a differentiated approach based on the active detection of SPDM. In the course of the study, it was proved that individual selection of CS therapy taking into account the presence of MT synthesis deficiency allows to achieve a 100% positive result of treatment in women of all four groups. Conclusions. Against the background of personalized treatment of CS in combination with SPDM in women, not only CS has been stopped, but also the level of QOL has been increased.
Editor's commentary to the article by Shishkina G.A. et al. «Analysis of treatment outcomes of patients with colorectal cancer in the context of the covid-19 pandemic»
Authors: Prudkov M. I. 
Published: March 2022

The editorial comment to the article «Analysis of Treatment Outcomes of Patients with Colorectal Cancer in the Context of the COVID-19 Pandemic» discusses changes caused by the COVID-19 pandemic in the contingents of patients with colorectal cancer and possibilities of intensification of their surgical treatment in conditions of temporary shortage of surgical beds. The structure of the patients operated routinely in the conditions of the specialized clinical department does not answer the question whether the structure of colorectal cancer has changed after the pandemic. At the same time the successful experience of the authors concerning the transition to endovideosurgical operations and the «fast-track» protocol testifies to the effectiveness and safety of intensification of colorectal cancer patients care in the conditions of temporary shortage of surgical beds.