bluuebunny/crossref_metadata_2025_split huggingface dataset:
Human milk‐sharing practices and infant‐feeding behaviours: A comparison of donors and recipients
Authors: Peregoy Jennifer A. , Pinheiro Giovana M. , Geraghty Sheela R. , Dickin Katherine L. , Rasmussen Kathleen M. 
Published: June 2022

AbstractHuman milk sharing (HMS) is growing in popularity as an infant‐feeding strategy in the United States. HMS families are a hidden population because HMS is a nonnormative and stigmatized behaviour. Thus, gaining access to HMS participants is challenging, and research on this topic remains limited. In particular, little is known about the broader infant‐feeding behaviours of HMS parents. This study aimed to describe and compare the infant‐feeding behaviours and HMS practices among a network of HMS donors and recipients. A detailed online survey was distributed to HMS parents in the Washington, DC region. Bivariate analyses were used to summarize the data by donor/recipient status when possible. Group differences were tested using analysis of variance for continuous variables and χ2 tests for categorical variables. Donors and recipients did not differ in their sociodemographic characteristics. Recipients were significantly more likely than donors to have experienced complications of labour and delivery, traumatic birth, postpartum depression or a negative breastfeeding experience. Donors and recipients did not differ significantly in their duration of lactation or HM‐feeding. Interestingly, 30% of recipients ever produced excess milk and 21% of donors ever had difficulty producing enough milk for their child. Compared with donors, recipients faced numerous maternal health challenges, but were still able to achieve a long duration of HM‐feeding. HMS recipients represent a vulnerable group who may benefit from additional psychosocial and lactation support to improve their health and breastfeeding outcomes. Additional research is needed to investigate the associations between HMS participation, infant‐feeding behaviours and lactation outcomes.
Radial and Axial Displacement of the Initially-Tensioned Orthotropic Arterial Wall Under the Influence of Harmonics and Wave Reflection
Authors: Hao Zhili 
Published: June 2022

Abstract
This study examines radial and axial displacement of the arterial wall under the influence of harmonics and wave reflection for the role of axial wall displacement in pulsatile wave propagation. The arterial wall is modeled as an initially-tensioned thin-walled orthotropic tube. In conjunction with three pulsatile parameters in blood flow, a free wave propagation analysis is conducted on the governing equations of the arterial wall and no-slip conditions at the blood-wall interface to obtain the frequency equation and pulsatile parameter expressions under different harmonics. The influence of wave reflection is then added to pulsatile parameter expressions. With the harmonic values of measured pulsatile pressure and blood flow rate at the ascending aorta in the literature, the waveforms of radial wall displacement, axial wall displacement, and wall shear stress are calculated under different orthotropicity and axial initial tension. The developed theory and calculated results indicate that (1) difference in waveform between blood flow rate, wall shear stress, and axial wall displacement is caused by harmonics, rather than wave reflection; (2) Axial wall displacement does not affect blood flow rate, radial wall displacement, and wall shear stress; (3) Besides wall shear stress, radial wall displacement gradient also contributes to axial wall displacement and its contribution is adjusted by axial initial tension; (4) different wave reflections only noticeably affect the maximum and minimum values of wall shear stress; and (5) The amplitude and waveform of axial wall displacement are predominantly dictated by axial elasticity and axial initial tension, respectively.
Enhanced Structural and Dielectric Properties of Calcium and Chromium-Based M-Type Hexagonal Ferrites with Polyvinyl Alcohol (PVA) Polymer Composites
Authors: Zahid Muhammad , Khan Hasan M. , Zaheer Beenish , Imran Muhammad , Assiri Muhammad A. , Rehman Aziz Ur , Batool Zahida 
Published: June 2022

[Formula: see text]-type hexagonal ferrites with compositions Ca[Formula: see text]CrxFe[Formula: see text]O[Formula: see text] at ([Formula: see text], 0.2, 0.3, 0.4, 0.5) were successfully prepared by sol–gel auto combustion method and then immersed with polyvinyl alcohol (PVA) by ultrasound-assisted in situ emulsion technique. The results indicate that the synthesized nanoparticles were diffused homogeneously in PVA retaining the size and shape of the particle. The single-phase [Formula: see text]-type hexagonal structure was revealed by X-ray diffraction (XRD) with extra 101 peak of PVA at 2[Formula: see text]. The suitable signal-to-noise ratio in the high density recording media can be achieved due to the small particle size of the prepared composites as compared to pure hexaferrites. The interaction between PVA and nanoparticles was confirmed by Fourier transform infrared spectroscopy (FTIR). Scanning electron microscopy (SEM) images revealed the homogeneous distribution of grains, the crystallite size was measured from SEM (25–38[Formula: see text]nm), and it is also in agreement as calculated from the Scherer formula. Dielectric properties were also explored in the range of 1 MHz–3 GHz frequencies. Dielectric constant and dielectric loss were found to decrease with increasing frequency and decrease with the addition of ferrite ratio in the polymer matrix. This impact is because of the grain boundary at low frequency regime. The occurrence of resonance at high frequency regime recommends the investigated samples for multilayer chip inductor.
RDF: A Reconfigurable Dataflow Model of Computation
Authors: Fradet Pascal , Girault Alain , Krishnaswamy Ruby , Nicollin Xavier , Shafiei Arash 
Published: June 2022

Dataflow Models of Computation (MoCs) are widely used in embedded systems, including multimedia processing, digital signal processing, telecommunications, and automatic control. In a dataflow MoC, an application is specified as a graph of actors connected by FIFO channels. One of the first and most popular dataflow MoCs, Synchronous Dataflow (SDF), provides static analyses to guarantee boundedness and liveness, which are key properties for embedded systems. However, SDF and most of its variants lack the capability to express the dynamism needed by modern streaming applications. In particular, the applications mentioned above have a strong need for reconfigurability to accommodate changes in the input data, the control objectives, or the environment.We address this need by proposing a new MoC called Reconfigurable Dataflow (RDF). RDF extends SDF with transformation rules that specify how and when the topology and actors of the graph may be reconfigured. Starting from an initial RDF graph and a set of transformation rules, an arbitrary number of new RDF graphs can be generated at runtime. A key feature of RDF is that it can be statically analyzed to guarantee that all possible graphs generated at runtime will be consistent and live. We introduce the RDF MoC, describe its associated static analyses, and present its implementation and some experimental results.
Evaluation of Sensitivity to Endocrine Therapy Index (SET2,3) for Response to Neoadjuvant Endocrine Therapy and Longer-Term Breast Cancer Patient Outcomes (Alliance Z1031)
Authors: Suman Vera J. , Du Lili , Hoskin Tanya , Anurag Meenakshi , Ma Cynthia , Bedrosian Isabelle , Hunt Kelly K. , Ellis Matthew J. , Symmans W. Fraser 
Published: June 2022

Abstract

Purpose:
To evaluate prediction of response and event-free survival (EFS) following neoadjuvant endocrine therapy by SET2,3 index of nonproliferation gene expression related to estrogen and progesterone receptors adjusted for baseline prognosis.

Experimental Design:
A correlative study was conducted of SET2,3 measured from gene expression profiles of diagnostic tumor (Agilent microarrays) in 379 women with cStage II–III breast cancer from the American College of Surgeons Oncology Group Z1031 neoadjuvant aromatase inhibitor trial SET2,3 was dichotomized using the previously published cutoff. Fisher exact test was used to assess the association between SET2,3 and low proliferation at week 2–4 [Ki67 ≤ 10% or complete cell-cycle arrest (CCCA; Ki67 ≤ 2.7%)] and PEPI-0 rate in cohort B, and the association between SET2,3 and ypStage 0/I in all patients. Cox models were used to assess EFS with respect to SET2,3 excluding cohort B patients who switched to chemotherapy.

Results:
Patients with high SET2,3 had higher rate of pharmacodynamic response than patients with low SET2,3 (Ki67 ≤ 10% in 88.2% vs. 56.9%, P &lt; 0.0001; CCCA in 50.0% vs. 26.2%, P = 0.0054), but rate of ypStage 0/I (24.0% vs. 20.4%, P = 0.4580) or PEPI = 0 (28.4% vs. 20.6%, P = 0.3419) was not different. Patients with high SET2,3 had longer EFS than patients with low SET2,3 (HR, 0.52, 95% confidence interval: 0.34–0.80; P = 0.0026).

Conclusions:
This exploratory analysis of Z1031 data demonstrated a higher rate of pharmacodynamic suppression of proliferation and longer EFS in high SET2,3 disease relative to low SET2,3 disease. The ypStage 0/I rate and PEPI = 0 rate were similar with respect to SET2,3.
Longitudinal Outcome over Two Decades of Unrelated Allogeneic Stem Cell Transplantation for Relapsed/Refractory Acute Myeloid Leukemia: An ALWP/EBMT Analysis
Authors: Nagler Arnon , Ngoya Maud , Galimard Jacques-Emmanuel , Labopin Myriam , Bornhäuser Martin , Stelljes Matthias , Finke Jürgen , Ganser Arnold , Einsele Herman , Kröger Nicolaus , Brecht Arne , Bethge Wolfgang , Edinger Matthias , Kulagin Aleksandr , Passweg Jakob , Blau Igor Wolfgang , Elmaagacli Ahmet , Schäfer-Eckart Kerstin , Platzbecker Uwe , Schroeder Thomas , Bunjes Donald , Tischer Johanna , Martin Sonja , Spyridonidis Alexandros , Giebel Sebastian , Savani Bipin , Mohty Mohamad 
Published: June 2022

Abstract

Purpose:
We evaluated outcomes of unrelated transplantation for primary refractory/relapsed (ref/rel) acute myeloid leukemia (AML), comparing two cohorts according to the year of transplant, 2000–2009 and 2010–2019.

Patients and Methods:
Multivariable analyses were performed using the Cox proportional-hazards regression model.

Results:
3,430 patients were included; 876 underwent a transplant between 2000–2009 and 2554 in 2010–2019. Median follow-up was 8.7 (95% CI, 7.8–9.4) and 3.4 (95% CI, 3.1–3.6) years (P &lt; 0.001). Median age was 52 (18–77) and 56 (18–79) years (P &gt; 0.0001); 45.5% and 55.5% had refractory AML while 54.5% and 44.5% had relapsed AML. Conditioning was myeloablative in 60% and 52%, respectively. Neutrophil recovery and day 100 incidence of acute and 2-year incidence of chronic graft-versus-host disease (GvHD) were similar between the two periods. Two-year relapse incidence was higher for patients undergoing transplant in the 2000–2009 period versus those undergoing transplant in 2010–2019: 50.2% versus 45.1% (HR, 0.85; 95% CI, 0.74–0.97; P = 0. 002). Leukemia-free survival; overall survival; and GvHD-free, relapse-free survival were lower for the 2000–2009 period: 26% versus 32.1% (HR, 0.87; 95% CI, 0.78–0.97; P = 0.01), 32.1% versus 38.1% (HR, 0.86; 95% CI, 0.77–0.96; P = 0.01), and 21.5% versus 25.3% (HR, 0.89; 95% CI, 0.81–0.99; P = 0.03), respectively. Two-year nonrelapse mortality was not significantly different (23.8% vs. 23.7%; HR, 0.91; 95% CI, 0.76–1.11; P = 0.34).

Conclusions:
Outcome of unrelated transplantation for patients with ref/rel AML has improved in the last two decades, rescuing about one third of the patients.
See related commentary by Adrianzen-Herrera and Shastri, p. 4167
Breakthrough Therapy Designation Criteria Identify Drugs that Improve Clinical Outcomes for Patients: A Case for More Streamlined Coverage of Promising Therapies
Authors: Collins Grace , Stewart Mark , McKelvey Brittany , Stires Hillary , Allen Jeff 
Published: June 2022

Abstract
The breakthrough therapy designation (BTD) process was created to expedite clinical development timelines for drugs intended to treat serious conditions and preliminary clinical evidence indicates the drug may demonstrate substantial improvement over existing therapies. This analysis demonstrates that BTD is a valuable tool for expediting approval of promising therapies in oncology. By comparing drugs indicated to treat non–small cell lung cancer (NSCLC) approved with BTD or without BTD between January 2013 and October 2021, BTD drugs reduced the risk of death by a median of 31% and progression by a median of 48%, while drugs never receiving BTD reduced the risk of death and progression by a median of 15% and 41.9%, respectively. These findings show that BTD criteria accurately identify drugs that improve long-term outcomes for patients with cancer and warrant coordinated efforts to ensure timely coverage decisions and access for patients.
Madness as a Form of Knowledge: Pavel Ivanovich Karpov's Creativity of the Mentally Ill
Authors: Jakovljević Branislav 
Published: June 2022

Abstract
Within the span of only four years, two books on the same subject and with almost identical titles were published on two sides of Europe: Hans Prinzhorn's Artistry of the Mentally Ill (Berlin, 1922) and Pavel Ivanovich Karpov's Creativity of the Mentally Ill (Moscow, 1926). Whereas the first book was recognized as one of the key steps in the “discovery” of the psychotic art and its eventual mainstreaming, the second one quickly fell into obscurity. Its author perished in Stalinist purges of the 1930s, together with a number of his colleagues from the Russian Academy of Artistic Science (RAKhN, 1921-1931), in which he served as the head of the Commission for the Creativity of Mentally Ill. This article is the first in-depth study of Karpov's book and his theory of creativity, which he based on his extensive collection of the works of his patients (which was also lost in the purges). The article argues that his approach to psychotic art is completely independent from Prinzhorn's. Instead, it places this book in the context of the specific form of Kunstwissenschaft that was practiced in RAKhN, suggesting that this placement is of primary importance for understanding Karpov's methods and aims. More specifically, the article argues that in his research on the creativity of the mentally ill, Karpov engages in a productive dialogue with the philosopher and prominent RAKhN member Gustav Shpet's work on epistemology from the same period. The result is an original contribution to the clinical literature on art of the mentally ill patients.
Scenes of Access, Politics of Difference
Authors: Karambeigi Pujan 
Published: June 2022

Abstract
Since the passing of the Americans with Disabilities Act in 1990, museum reformers have struggled to comply with the federal codes for accessibility. This essay accounts for the ambitions and limitations of these debates around access in the museum that were caught in the double bind between public expectation and private market forces, ultimately giving rise to a particular type of bottom-up reform organized around parametric gradients and attitudinal shifts. It does so by juxtaposing manuals for museum educators from the 1990s with artworks by New York City–based artists such as Carolyn Lazard, Jordan Lord, and Park McArthur who all worked with the incorporation of access into their artistic practice during the 2010s. The essay argues that these artistic practices force us to decouple the teaching of access from its narrow focus on shifting individual attitudes and instead belabor the form and content of stories about structural conditions.
Miklós Erdély, Ernst Bloch, Kurt Gödel, and Hidden Green
Authors: Hornyik Sándor 
Published: June 2022

Abstract
The introductory text interprets Eszter Bartholy's article about Miklós Erdély's exhibition Hidden Green. Bartholy's article is based on an interview with Erdély, and contain direct and indirect quotes from one of the most significant Hungarian neo-avant-garde artist. The introductory text describes how Erdély's own interpretation of his exhibition Hidden Green is present in Bartholy's article. Bartholy's analysis of Hidden Green sheds light on the way that Erdély combines ars poetica and art theory, while directly reflecting on utopia and on the social function and significance of art. While the text about Hidden Green seems like the interpretation of an exhibition, Bartholy and Erdély, in a virtual dialogue with thinkers including Ernst Bloch, Kurt Gödel, and Allan Kaprow, also make categorical claims about art theory and social theory. The introductory text argues that Erdély's Hidden Green and Bartholy's article connected and confronted–in the spirit of neo-avant-garde montage techniques–Hungarian popular and folk culture, Marxist aesthetic theories of utopias, and the paradoxes of modern natural sciences.
Thyroid Lymphoma: Case Series Review
Authors: Rezkallah Emad , Hanna Ragai S. , Elsaify Wael M. 
Published: June 2022

Background Primary thyroid lymphoma (PTL) is a rare malignancy accounting for about 5% of all thyroid malignancies and less than 2% of extra-nodal lymphomas. Diffuse B-cell lymphoma is the most common pathological subtype of PTL. Patients and methods This is a retrospective review of all patients diagnosed with thyroid lymphoma in our hospital during the period from 2011 to 2021. All patients had clinical, radiological, and pathological evaluation. We have followed up these patients since diagnosis till now. Results Eight patients were included in our review. Four patients were males and four were females. Mean age at diagnosis was 63 ± 32 years of age. Diagnosis was confirmed only with tissue histology. Six patients had stage IIE disease and two had stage IVE disease. Four patients had disease related mortality. Of the other four patients, two had chemotherapy (RCHOP) and one had local radiotherapy; all achieved complete remission, and the last one had hemithyroidectomy to relieve airway compression and still under treatment. Conclusion Primary thyroid lymphoma is rare malignancy of the thyroid gland. Advanced stage and age at the time of diagnosis, the presence of compression manifestations, large tumor mass, and presence of distant metastasis, all are poor prognostic criteria. Our knowledge of the disease pathology, diagnosis, and management is still limited and more research studies are required.
Longitudinal Associations Between Serum Bilirubin Level and Carotid Atherosclerosis Plaque in a Health Screening Population
Authors: Qin Lu , Li Lin , Fan Hongzhen , Gu Yongsheng , He Weiliang , Zhang Kaihua , Sun Yingru , Zhao Wannian , Niu Xiaoli , Wei Ci , Li Litao , Wang Hebo 
Published: June 2022

This study aimed to determine the relationship between bilirubin levels and carotid atherosclerosis (CAS) in the health screening population. After propensity score matching, this retrospective cohort study included 4360 subjects who underwent health examinations regularly in Hebei General Hospital between January 2010 and December 2019 and had no carotid plaque at baseline. After an average follow-up of 26.76 months, the main endpoint Cox regression analysis of carotid plaques was performed. After adjusting the confounding factors, Cox regression analysis showed that when serum total bilirubin (TBIL) and unconjugated bilirubin (UCB) increased by 1 standard deviation (SD), the risk of carotid plaque decreased by 7.30% (95% confidence interval (CI): 2.80–11.60%) and 15.70% (95% CI: 11.40–19.80%), respectively. When conjugated bilirubin (CB) increased by 1 SD, the risk of carotid plaques increased by 24.3% (95% CI: 19.7–29.0%). TBIL and UCB levels were negatively associated with CAS, and CB levels were positively associated with CAS.
Interpregnancy interval after a miscarriage and obstetric outcomes in the subsequent pregnancy in a low-income setting, Nigeria: A cohort study
Authors: Lawani Lucky Osaheni , Enebe Joseph Tochukwu , Eze Paul , Igboke Francis Nwabueze , Ukaegbe Chukwuemeka Ikeji , Ugwu Monica Omosivie , Agu Ujunwa Justina , Onyinye Enebe Nympha , Iyoke Chukwuemeka Anthony 
Published: June 2022

Objectives: The aim of this study was to determine and compare the occurrence of adverse pregnancy outcomes in a cohort of pregnant women with interpregnancy interval of < and ⩾6 months (short and normal interpregnancy interval, respectively) following a spontaneous miscarriage in their last pregnancies. Methods: This was a cohort study that involved pregnant women with a spontaneous pregnancy loss in their last pregnancies. They were recruited at a gestational age of 13–15 weeks and followed up to determine the obstetric and foetal outcomes of their pregnancies at four tertiary hospitals in Nigeria from July 2018 to September 2019. Data collected were analysed using SPSS version 26.0. A Chi-square and multivariate logistic regression analysis were done, and a p-value of less than 0.05 was assumed to be statistically significant. Results: A total of 705 participants were studied, out of which 448 (63.5%) and 257 (36.5%) of the participants had short and normal interpregnancy interval after a spontaneous miscarriage. Over 80% of the participants had first-trimester pregnancy losses and were managed with manual vacuum aspiration in 73.3% of the cases. The majority, 87.5% for the normal interpregnancy interval cohort and 86.4% for the short interpregnancy interval cohort, had live births, while 8.5% and 10.1% of the women in the normal and short interpregnancy interval cohorts, respectively, had repeat miscarriages. There was no statistical difference in the occurrence of live births and repeat miscarriages between both cohorts (p > 0.05). There was no increased risk of occurrence of adverse foetomaternal outcomes in both groups (p > 0.05). Multivariate logistic regression analysis showed that there was no statistical difference in the occurrence adverse foetomaternal outcomes between the studied cohorts (p > 0.05). Conclusion: There was no significant difference in the occurrence of adverse maternal and foetal outcomes in the cohorts of mothers with short and normal interpregnancy interval following miscarriages in their last previous pregnancies.