bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of time restricted feeding on anthropometric measures, eating behavior, stress, brain derived neurotrophic factor (BDNF) and lipopolysaccharide binding protein (LBP) levels in women with overweight/obesity and food addiction: a study protocol for a randomized clinical trial
Authors: Irani Hanieh , Khodami Banafsheh , Abiri Behnaz , Saidpour Atoosa 
Published: May 2022

Abstract
Background: Food addiction is one of the behavioral factors that plays an important role in the pathogenesis of obesity. Much evidence is available suggesting intestinal microbiomes can play a role in eating behavior, body composition and BDNF levels, and they can be modified by Time-Restricted Feeding (TRF). So, this study will aim to evaluate the effect of TRF on anthropometric measures, eating behavior, stress, serum BDNF and LBP levels in women with overweight/obesity and food addiction.Methods: we will carry out a randomized clinical trial for 8 weeks to evaluate the effect of a TRF on anthropometric measures, eating behavior, stress level, serum BDNF and LBP levels in women with overweight/obesity and food addiction.Discussion: Given the effect of BDNF on regulating eating behavior and body weight and the effect of dietary restrictions on BDNF and the gut microbiome, the TRF diet could possibly be a new way to successfully manage weight through modifying BDNF in people with eating disorders, including food addiction.Trial Registration: Iranian Registry of Clinical Trials. IRCT20131228015968N7. Registered on 2020-10-25.
sobre conexões que transcendem o controle
Authors: Lira Ana 
Published: May 2022

This is a text by the Brazilian artist, photographer, curator, storyteller, editor, and articulator Ana Lira, that provides a preface to the writings gathered in South Boom Boom: this special section of the Performance Philosophy journal. In the text, Lira reflects on how the texts demonstrate different layers of refusal to the "visible and symbolic violence, which gains new contours in each cycle, continues to (de)mark creative lives even in territories that claim to be revising their "colonial pasts, structures and methodologies."
Reflections on curatorial articulation practices. A collective doing: that's why I don't write alone
Authors: Lopes Mario 
Published: May 2022

In this text, Brazilian artist Mario Lopes addresses how he redefines and reuses the word "curatorship" through his practices according to nine specific steps and introduces the idea of Afrotranstopia. As Lopes explains: “For a long time, the term "curator" has triggered noises and conflicts in me. I question the practices and market logics operating within our viral system, which I call PACACO-bi: Patriarchy, Capitalism and Colonialism within a binary structure. I name "PACACO-bi" this syndemic virus of our history, which affects us as humanity and governs us as a society. For this reason, considering myself a curator is a permanent conflict in each experience where I act as such. I try to exercise a curatorial practice that, on principle, combats this viral system, constantly asking myself: Is it possible to break with the logics immanent to the capitalist system, at the same time freeing myself from the patriarchal place of power? Is it possible to overcome the binary logic and colonial methods of action pervading social relations?”
El pensamiento selvage
Authors: Pinheiro Flavia 
Published: May 2022

This is a text by the Brazilian artist Flavia Pinheiro. For Pinheiro, “This essay is an attempt to ask—in a frustrated and submerged, tear-sunken technology of wording and on behalf of the ones who never had the right to live or who do not belong, or those who have never been here, for those who died right after birth—what it could be if we dream and act together, towards indiscipline and disruption of macrostructures”.
Sub-Atlantic Abyss
Authors: Andreatta Isis 
Published: May 2022

This is a text by the Brazilian dance maker, choreographer and performer Isis Andreatta. For Andreatta, “This writing is a reverie about inhabiting the abyss of sub-atlantic life. An outline of a storytelling about subverting physical and metaphysical margins. Diving. A confident act of raving deliriously along the edges is a way of existing beyond the stigmas of “Terra Firme”. For her, this text is a gesture to embody fiction as a commitment with a non hegemonic imaginary and an alliance between anticolonial, anti-racist and anti-manicomial practices.
Al2O3 encapsulated by calcium alginate as composite for efficient removal of phosphate from aqueous solutions: batch and column studies
Authors: Ai Huiying , Xu Lei , Zhang Zhiyong , Hu Xiaoya , Chen Chen , Sun Wenjie , Fu Ming-Lai , Yuan Baoling 
Published: May 2022

Abstract
Activated alumina (Al2O3) has been widely used to remove aqueous anionic pollutants such as phosphate for preventing the eutrophication phenomenon. While Al2O3, as a fine powder material, cannot be stably packed into continuous flow treatment, which limits its practical applications. Herein, we proposed a new strategy in which Al2O3 was encapsulated by calcium alginate (CA) to fabricate Al2O3/CA composite, which has relatively large particle size and can be suitable for application in columns. The BET surface area of Al2O3/CA increased to 51.73 m2/g compared with 37.31 m2/g of Al2O3. The maximum adsorption capacity of phosphate on Al2O3/CA was estimated at 1.92-fold compared with that of pure Al2O3 by Langmuir fitting. The main mechanism of phosphate adsorption was the formation of aluminum phosphate precipitation. Moreover, the column studies showed that the adsorption of phosphate on Al2O3/CA was affected by the amount of outer calcium alginate, bed height, influent flow rates and phosphate concentration. This study demonstrated that Al2O3/CA composite has better adsorption capacity and can be used in the dynamic adsorption system as a promising approach for phosphate removal from water.
HIGHLIGHTS Al2O3/CA composite was synthesized by encapsulating Al2O3 in calcium alginate. The BET surface area of Al2O3/CA increased 1.39-fold compared with pure Al2O3. Al2O3/CA with larger particle size can be easily separated from the water. The optimal conditions for dynamic adsorption of in fixed-bed column were investigated.
Structural and Functional Analyses of SARS COV-2 RNA-dependent RNA Polymerase Protein and Complementary vs. Synthetic Drugs against COVID-19 and the Exploration of Binding Sites for Docking, Molecular Dynamics Simulation, and Density Functional Theory Studies
Authors: Unar Ahsanullah , Imtiaz Mahrukh , Trung Truong Tan , Rafiq Maria , Fatmi Muhammad Qaiser , Jafar Tassadaq Hussain 
Published: May 2022

Background:RNA-dependent RNA polymerase (RdRp) contributes to the transcription cycle of the SARS-CoV-2 virus with the possible assistance of nsp-7-8 cofactors.Objective:To investigate the viral protective effects of complementary drugs in computational approaches that use viral proteins.Methods:For the in silico studies, the identified compounds were subjected to molecular docking with RdRp protein followed by structural and functional analyses, density functional theory (DFT), and molecular dynamics (MD) simulation. The 3D structure of RdRp (6m71 PDB ID) was obtained from the protein databank as a target receptor. After reviewing the literature, 20 complementary and synthetic drugs were selected for docking studies. The top compounds were used for DFT and MD simulation at 200 ns. DFT of the compounds was calculated at B3LYP/6-311G (d, p) based on chemical properties, polarizability, and first-order hyperpolarizability. Results were analyzed using USCF Chimera, Discovery Studio, LigPlot, admetSAR, and mCule.Results:Computational studies confirmed the potent interaction of the complementary drugs forsythiaside A, rhoifolin, and pectolinarin with RdRp. Common potential residues of RdRp (i.e., Thr-556, Tyr-619, Lys-621, Arg-624, Asn-691, and Asp-760) were observed for all three docking complexes with hydrogen bonding. Docking analysis showed strong key interactions, hydrogen bonding, and binding affinities (-8.4 to −8.5 kcal/mol) for these ligands over the FDA-approved drugs (−7.4 to −7.6 kcal/mol). Docking and simulation studies showed these residues in the binding domains.Conclusion:Significant outcomes of novel molecular interactions in docking, simulation, DFT, and binding domains in the structural and functional analyses of RdRp were observed.
Manganese-Catalyzed Radical 6-endo Azacyclization of 2-Alkynylbenzamide
for the Synthesis of 3-Hydroxylisoquinolin-1,4-dione
Authors: Cheng Xiya , Yan Xiaoyang , Li Meng , Yadav Sarita , Lin Yanfei , Qiu Guanyinsheng 
Published: May 2022

Backgroup:
The versatile 2-alkynylbenzamde has been reported to produce many privileged skeletons, like isoquinolin-1-ones, isocoumarin-1-imines, isoindolin-1-ones, and isobenzofuran-1-imines. Recently, we reported the projected transformation using copper salt (CuCl2) as a catalyst under O2 atmosphere. To expand the scope of reaction we used another inexpensive metal salt MnO2 as catalyst

Methods:
The paper aims at exploring a manganese-catalyzed reaction of 2-alkynylbenzamide under O2 balloon for the synthesis of 3-hydroxylisoquinolin-1,4-dione.

Results:
Results on reaction scope shows the 10 mol% MnO2 in O2 atmosphere and DCE solvent catalyzed the cyclization of 2-alkynylbenzamide to produce 3-hydroxylisoquinolin-1,4-diones in 40-68% isolated yields. The reaction proceeds through a regioselective N-center radical 6-endo-dig aza-cyclization pathway.

Conclusion:
We have developed a manganese-catalyzed cyclization of 2-alkynlbenzamide for the synthesis of 3-hydroxylisoquinolin-1,4-diones under O2 balloon. It is believed that the N-center radical-based 6-endo dig aza-cyclization proceeded in a regioselective manner.
Relationship Between Protein Intake in Each Traditional Meal and Physical Activity: Cross-sectional Study
Authors: Shinto Takae , Makino Saneyuki , Tahara Yu , Nitta Lyie , Kuwahara Mai , Tada Ayako , Abe Nanako , Michie Mikiko , Shibata Shigenobu 
Published: May 2022

Background
Protein intake plays an important role in the synthesis and maintenance of skeletal muscles for the prevention of health risks. It is also widely known that physical activity influences muscle function. However, no large-scale studies have examined the relationship between daily dietary habits, especially the timing of protein intake, and daily physical activity.

Objective
The purpose of this cross-sectional study was to investigate how protein intake and composition (involving the 3 major nutrients protein, fat, and carbohydrate) in the 3 traditional meals (breakfast, lunch, and dinner) are associated with physical activity.

Methods
Using daily dietary data accumulated in the smartphone food log app “Asken” and a web-based cross-sectional survey involving Asken users (N=8458), we analyzed nutrient intake and composition, as well as daily activity levels. As very few individuals skipped breakfast (1102/19,319 responses, 5.7%), we analyzed data for 3 meals per day.

Results
Spearman rank correlation analysis revealed that breakfast and lunch protein intakes had higher positive correlations with daily physical activity among the 3 major macronutrients (P<.001). These findings were confirmed by multivariate logistic regression analysis with confounding factors. Moreover, participants with higher protein intake and composition at breakfast or lunch tended to exhibit significantly greater physical activity than those with higher protein intake at dinner (P<.001).

Conclusions
Among the 3 macronutrients, protein intake during breakfast and lunch was closely associated with daily physical activity.
Metabolomic profiles as a new understanding of disease processes
Authors: Zolnikova O. Yu. , Reshetova M. S. , Ivanova M. N. , Ivashkin V. T. 
Published: May 2022

Aim. This review will demonstrate possibilities of using metabolomic profiling to identify biomarkers of various internal organs diseases.Key points. A new diagnostic direction is associated with high-sensitive spectral analysis of biomarker molecules. This review will discuss some of the latest advances with an emphasis on the use of metabolomics to identify major metabolic changes in various diseases. The possibility of finding diagnostic markers in diseases of the gastrointestinal tract, respiratory and cardiovascular systems, in oncology, endocrinology, neurology are discussed. These results define new potential therapeutic strategies, making metabolomics useful for a wide range of biomedical and pharmaceutical research.Conclusion. Metabolomic profile changes in different types of diseases will help to improve understanding of the pathogenesis. New therapeutic approaches may be developed. They will take into account individual characteristics of the patient, identified by using current molecular technologies. The results of metabolomic studies can be used to monitor treatment outcomes.
Inflammation, impaired motor function and visceral hypersensitivity: the main mechanisms of functional disorders of the gastrointestinal tract (materials of the Expert Council and literature review)
Authors: Ivashkin V. T. , Maev I. V. , Trukhmanov A. S. , Sheptulin A. A. , Lapina T. L. , Simanenkov V. I. , Sokolov K. A. 
Published: May 2022

Aim. To review the main mechanisms of functional disorders of the gastrointestinal tract and to present the materials of an Expert Council, which was held on 10 December 2021 in Moscow.Key points. The pathogenesis of the most common functional diseases of the gastrointestinal tract — functional dyspepsia (FD) and irritable bowel syndrome (IBS) is multifactorial and includes motor disorders of various parts of the gastrointestinal tract, visceral hypersensitivity, changes in the intestinal microbiome, impairment of the permeability of the protective barrier, low-grade inflammation of the gastrointestinal mucosa, etc. This often leads to the prescription of a complex of various medications to such patients, which increases the risk of undesirable drug interactions and side effects. Multitargeted therapy involves the use of drugs that simultaneously affect different pathogenetic links. One of these drugs is Iberogast®, which normalizes gastrointestinal motility and visceral sensitivity, has an anti-inflammatory action and is highly effective in treatment of FD and IBS.Conclusion. In the treatment of functional gastrointestinal diseases characterized by multifactorial pathogenesis, preference should be given to multi-targeted therapy with the use of drugs that have an effect on its various links.
Supplement to the Article “On Relations in Science: the Case of the Scientific Journal Editorial Board”
Authors: Bolshakov D. Yu. 
Published: May 2022

In this supplement it is shown that the dependences of the number of path lengths between vertices in the graph (between reviewers) and the number of connections of reviewers for the last few years that were discussed in Bolshakov’s article “On relations in science: the case of the scientific journal editorial board” are subordinate to the known statistical distributions. These data may allow us to draw a conclusion about the scientific journal editorial board’s functioning.See the article: Bolshakov D.Yu. On relations in science: the case of the scientific journal editorial board. Scholarly Research and Information. 2021;4(1–2):19–28. https://doi.org/10.24108/2658-3143-2021-4-1-2-19-28
COVID-19.rf: Information Against Pandemics: Project Goals and Results
Authors: Zeldina M. M. , Kosyakov D. V. , Kuznetsov A. Yu. , Lebedev V. V. , Malyshev A. V. , Razumova I. K. , Shvartsman M. E. 
Published: May 2022

The work reports implementation of the “COVID-19.rf: information against the pandemic” project.Since 2020, dozens of projects have been implemented to create collections of national COVID-19 publications and populate national COVID-repository platforms.The Russian project “COVID-19.rf: information against the pandemic” is among them. The following tasks were realized during the development of the COVID-19.rf repository: the program software to create and populate the project platform; automated data exchange with previously created Russian platforms; monitoring global citation indexes: Web of Science, Scopus, Dimensions and the Lens and automatic population of the created platform: possibility for access and downloading the project data via API under the OAI PMH protocol; project advancement and user training; indexing of the project content on the international integrator platforms: CORE, OpenAire: COVID-19 Open Research Gateway and Google Academy.As a result, algorithms and technical implementation of automatically replenishing of repositories within the legal framework of publishers’ license have been developed.By the beginning of 2022, metadata about 7380 Russian COVID publications were uploaded to the project platform, 3923 articles being in full text. These indicators put the Russian project on a par with the largest national projects such as of the Great Britain, Spain and Brazil.
Fake online review recognition algorithm and optimisation research based on deep learning
Authors: Hou Jiani , Zhu Aimin 
Published: May 2022

Abstract
With the rapid development of the e-commerce industry, online reviews of goods are a great help for consumers to make decisions. With the sharp increase in online order for goods and the explosion of product reviews, some merchants began to hire consumers to make fake purchases for profit, which led to the problem of identifying fake reviews. In this paper, we propose a method that uses feature engineering to eliminate the comments of false reviewers and combines convolutional neural network and recurrent neural network to classify and recognise reviews from the perspective of text. Traditional neural network models such as CNN, LSTM and BILSTM are compared with the hybrid model proposed by the text. The model is optimised by pre-training on the Baidu Baike commodity review database instead of the initial randomising word vector. The experimental results show that the combination of convolutional neural network and recurrent neural network can better extract the global and local features of false comments, and the model has a good effect. The updating of the pre-trained word vector makes the recognition effect of each model better.
Validity and reliability analysis of the Chinese version of planned happenstance career inventory based on mathematical statistics
Authors: Si Shoujing , Ding Hui 
Published: May 2022

Abstract
To revise the Chinese version of Planned Happenstance Career Inventory (PHCI), a total of 1161 college students were recruited in the study, among whom 327 were used for item analysis and exploratory factor analysis (EFA), 568 for further confirmatory factor analysis (CFA) and internal consistency reliability analysis, and 266 were retested after a four-week interval for test-retest reliability analysis. Occupational Development Contingency Scale (ODCS), CAAS-China were chosen as the criterion-related indication. The scale consisted of 20 items, and the EFA produced five factors, which accumulatively explained the variance of total variance by 58.15%. The CFA showed that the 5-factor model fits well. The internal consistency reliability of sample measurement was 0.862, retest reliability coefficients was 0.871, and the split-half reliability coefficients was 0.733. The Chinese version of PHCI has acceptable reliability and validity and can be used to measure career planning for Chinese college students.
KEMAMPUAN ARGUMENTASI DAN KEMAMPUAN LITERASI SAINS PESERTA DIDIK KELAS XI MIPA PADA MATERI SEL
Authors: Fadlika RistiHilda , Hernawati Diana , Meylani Vita 
Published: May 2022

Kemampuan Argumentasi dan Kemampuan Literasi Sains Peserta Didik Kelas XI MIPA Pada Materi Sel. Pendidikan abad 21 menuntut peserta didik untuk mengembangkan kemampuan argumentasi dan literasi sains. Untuk itu penelitian ini bertujuan untuk mengetahui korelasi antara kemampuan argumentasi dan literasi sains pada materi sel di kelas XI MIPA SMA Negeri 22 Kabupaten Tangerang. Penelitian ini dilaksanakan pada bulan November 2020 – Januari 2021. Metode penelitian yang digunakan adalah korelasional. Sampel yang digunakan berjumlah 38 orang dengan teknik pengambilan sampel secara purposive sampling. Instrumen penelitian yang digunakan berupa soal uraian kemampuan argumentasi yang mengacu pada indikator Toulmin dan soal uraian kemampuan literasi sains yang mengacu pada PISA. Hasil kemampuan argumentasi diukur menggunakan soal uraian yang terdiri dari 13 soal kemampuan argumentasi dan 16 soal kemampuan literasi sains. Teknik analisis data yang digunakan yaitu uji korelasi bivariat. Hasil penelitian disimpulkan terdapat korelasi antara kemampuan argumentasi dengan literasi sains peserta didik dengan koefisien korelasi sebesar 0,426 dengan kategori sedang.
Kata kunci: Korelasi; Kemampuan Argumentasi; Kemampuan Literasi Sains
ABSTRACT
Argumentation ability and science literacy in cell material in grade XI MIPA SMA Negeri 22 Tangerang Regency. 21st century education requires learners to develop the skills of argumentation and science literacy. Therefore, this study aims to find out the correlation between argumentation ability and science literacy in cell material in grade XI MIPA SMA Negeri 22 Tangerang Regency. This research was conducted in November 2020 – January 2021. The research method used is correlational. The samples used amounted to 38 people with purposive sampling techniques. The research instrument used is a description of argumentation ability that refers to the Toulmin indicator and a description of science literacy ability that refers to PISA. The results of argumentation ability are measured using a description question consisting of 13 questions of argumentation ability and 16 questions of science literacy ability. The data analysis technique used is bivariate correlation test. The results concluded that there is a correlation between the ability of argumentation and science literacy of learners with a correlation coefficient of 0.426 with a moderate category.
Keywords: Correlation; Argumentation Ability; Science Literacy Ability
Penerapan protokol kesehatan pada kompetisi sepak bola BRI Liga 1 dan Liga 2 Indonesia
Authors: Wicaksono Arif , Asyhar Alfan Nur 
Published: May 2022

Pada awal tahun 2020 terjadi pandemi Coronavirus 2019 (COVID-19). Pandemi ini mengubah keseharian manusia termasuk olahraga. Penyakit COVID-19 sangat menular melalui droplet atau kontak dengan benda yang terkena droplet pasien yang terinfeksi. Cara mencegah penularan paling baik adalah dengan menjaga jarak dan tidak berkerumun. Hal ini menyebabkan olahraga yang bersifat kontak dan mengumpulkan orang banyak dihentikan atau ditunda pelaksanaannya termasuk kompetisi sepak bola. Berhentinya kompetisi sangat mempengaruhi banyak sector, tidak hanya tim, atlet, seluruh pihak lain yang terlibat menjadi kehilangan mata pencaharian. Dilema antara berhentinya kompetisi untuk mencegah penyakit dan melakukan kompetisi di tengah pandemi menjadi dasar tujuan penulisan artikel ini yaitu adanya protokol kesehatan untuk kompetisi sepak bola di Indonesia. Artikel ini merupakan telaah literatur dengan jurnal, buku, panduan, dan artikel dari dalam dan luar negeri yang didapatkan selama tahun 2020-2021. Kompetisi sepak bola dapat dilakukan menggunakan protokol kesehatan yang ketat untuk mencegah kasus pada saat kompetisi berlangsung. Protokol kesehatan pada kompetisi sepak bola dapat dijadikan rekomendasi untuk kompetisi olahraga yang lain.