bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation of Fiber Properties of Eucalyptus globulus grown in Farta Woreda as Potential Source for Pulp and Paper Making, Amhara National Regional State, Ethiopia
Authors: Gebeyehu Daniel , Abara Lamesa , Genene Degnechew 
Published: September 2022

Abstract

The aim of this study was to investigate the fiber properties and pulp and paper-making potential of Eucalyptus globulus grown in Farta Woreda, Amhara National Regional State, Ethiopia. Six trees with an age of eight years were sampled, and sample discs were taken at the bottom (10%), middle (50%) and top (90%) along the tree height, as well as 2x2x2 cm blocks of wood at 10%, 50% and 90% of the disc radius (distance from the pith to the bark of the tree). Fiber properties were determined, and their variation along tree height and transversally from pith to bark was evaluated. The results showed that the overall mean values along tree height and distance from the pith to the bark were 0.77mm for fiber length, 12.38µm for fiber diameter, 2.94µm for cell wall thickness, 8.23µm for lumen diameter, 19.61µm for fiber width, 0.74 for runkel ratio, 39.22% for slenderness ratio, 67.83% for flexibility coefficient, and 0.47 for wall coverage ratio. Fiber length, lumen and fiber diameter, fiber width, cell wall thickness, runkel, and wall coverage ratio decreased from the bottom to the top of the tree, while they increased transversally from the pith to the bark, except for lumen diameter and flexibility coefficient, which decreased transversally from the pith to the bark, whereas the flexibility coefficient value increased from the bottom to the top of the tree height. Slenderness ratio did not show significant variation along tree height, while it showed an increase transversally from the pith to the bark.
Comparison of fludarabine/melphalan (FluMel) with fludarabine/melphalan/BCNU or thiotepa (FBM/FTM) in patients with AML in first complete remission undergoing allogeneic hematopoietic stem cell transplantation – a registry study on behalf of the EBMT Acute Leukemia Working Party.
Authors: Duque-Afonso Jesus , Finke Jürgen , Ngoya Maud , Galimard Jacques-Emmanuel , Craddock Charles , Raj Kavita , Bloor Adrian , Nicholson Emma , Eder Matthias , Kim Orchard , Valerius Thomas , Snowden John , Tholouli Eleni , Crawley Charles , Collin Matthew , Wilson Keith , Gadisseur Alain , Protheroe Rachel , Wagner-Drouet Eva , Savani Bipin , Spyridonidis Alexandros , Ciceri Fabio , Nagler Arnon , Mohty Mohamad 
Published: September 2022

Abstract
The authors have requested that this preprint be removed from Research Square.
Outcomes, toxicities and dosimetric comparison of different hypofractionated Intensity modulated Radiotherapy techniques for treatment of Localized Prostate Cancer
Authors: Elzawawy Sherif , Hewala Taha , Elzayat Doaa , Hammam Ramadan 
Published: September 2022

Abstract
Background: conventional fractionation IMRT is the standard treatment for localized prostate cancer patients. The objectives of this study were to evaluate safety and efficacy of Hypofractionated radiotherapy with dosimetric comparison between 5, 7 and 9 IMRT fields.
Methods: Low or intermediate risk patients included. Three sets of Inverse planning IMRT were carried out (5, 7 and 9 Fields) for each patient with total dose of 70 Gy/ 28 fractions.
Results: 20 patients were recruited. Regarding PTV coverage, there were no statistically significant differences regarding D2%, D5%, D50%, D95%, D98%, Dmax, Dmin, Dmean, conformity index, homogeneity index, between 5, 7 or 9 Fields. (p= 0.25, 0.38, 0.969, 0.057, 0.294, 0.057, 0.517, 0.969, 0.313 and 0.969, respectively). Statistically significant difference regarding longer treatment time (p= 0.039) and more monitor units (p= 0.015) between 5 and 9 fields with no significant difference between 7 and 9 fields. The mean doses to V25%, V35% and V50% of the rectum were significantly higher for the 5 fields compared to 7 and 9 fields (p=0.001, 0.001, 0.006). The 2 year biochemical control rate was 95% and the DFS was 100%. Acute gastero intestinal toxicities G1 55%, G2 40% and G3 5% while late toxicities G1 25% and G2 15%. Acute genitourinary toxicities G 1 60%, G2 35% and G3 5% and for late toxicities G1 30% and G2 10%. No late G3 nor G4 toxicities were observed.
Conclusion: Hypofractionated radiotherapy is safe and effective regarding the biochemical control and toxicity profile, more convenient and less costly.
Anatomical Characteristics of the Cast Tibial Intraosseous Artery
Authors: Wan Jiaming , Wang Hongyu , Zhang Yan , Zhang Xiangnan , Hou Ruixing 
Published: September 2022

Abstract
Background
Nonunion after tibial fracture is predominantly related to insufficient blood supply. Characterization of the anatomy of the tibial intraosseous artery is necessary to explore and develop therapeutic measures to prevent nonunion. However, quantitative indicators related to the tibial intraosseous artery are currently lacking. This study aimed to prepare pig tibia specimens with exposed intraosseous arteries and use these specimens to examine the anatomical characteristics of tibial intraosseous arteries.
Methods
Twenty isolated pig right legs with intact blood vessels were used to create cast specimens of the porcine tibia intraosseous artery by the perfusion corrosion method. The course, distribution, and branches of the intraosseous nutrient artery were observed with naked eye and optical microscopy. Intraosseous arteries with a diameter of ≥ 0.3 mm were counted and their diameters were measured using a microscopic ruler. The spatial distribution of each artery branch was determined using a circular protractor and a laser generator, and the obtained data were statistically analyzed.
Results
Porcine tibial intraosseous artery cast specimens were successfully produced and intraosseous arteries were clearly visible. The internal tibial artery is divided into the main trunk of the ascending and descending branches. The main trunk of the ascending branch sends out two primary branches, and each primary branch sends out 1–3 secondary branches. The branches are connected by communicating branches to form a circular anastomosis and merge into the proximal tibia. The main trunk of the descending branch descends for a certain distance in the medullary cavity and then divides into two primary branches, with each primary branch further dividing into 1–3 tree-like secondary branches that merge into the distal end of the tibia. The number of ascending and descending secondary branches of intraosseous arteries (diameter ≥ 0.3 mm) were 3.5 ± 0.71 and 2.63 ± 0.59, respectively, and the diameters of these branches were 0.56 ± 0.09 and 0.57 ± 0.11 mm, respectively.
Conclusion
This study quantitatively described the diameter, number, and distribution of pig tibial intraosseous arteries and provides a potential new method to study human tibial intraosseous arteries. Furthermore, these findings provide guidance for safe intraoperative fixation and reconstruction of blood supply to the broken end of the tibia.
Prevalence of low birth weight and associated factors among neonates born at Bale Zone,Oromia Region, Ethiopia 2019
Authors: Segni Mesfin Tafa , Gebretsadik Solomon , Worku Girma 
Published: September 2022

Abstract
Background: Low birth weight continues to be a significant public health problem globally and is associated with a range of both short- and long term consequences. Ethiopia, having an infant mortality rate of 59/1000 live births and has limited data on birth weight estimates as most deliveries take place at home leading to a highly biased maternal subjective inclusion of a “very small baby” in the reports. The aim of this study was to assess the prevalence and associated factors of low birth weight among neonates delivered at Raitu district health facilities, Bale zone ,Ethiopia.
Methods: Institutional based cross-sectional Study design was applied from September 01 to October 15, 2019 among 374 neonates consecutively selected at Rayitu district public health facilities. The collected data was coded and entered into Epidata version 3 and exported to SPSS version 20 for data analysis. Logistic regression was used to determine the association between dependant and independent variables. In bi-variable analysis co-variates with P-value of less than 0.25 was included in malty aviate analysis. The final model was interpreted using AOR with 95%; CI at P-value of less than 0.05.
Result: The prevalence of low birth weight at the study area was 5.3%. Among the 374 singleton live births in the study, 20 were low birth weight. Having family size >4 was 3.72 times (3.71(95%; CI; (1.34-10.38)) more likely has low birth weight. Mothers whose MUAC was <22cm were 4.96 times (AOR=4.96; 95%; CI (1.58-15.51)) more likely deliver low birth weight infants. Mothers whose CHO FFS of poor was 3.28 times(AOR=3.24; 95%;CI;(1.03-10.39)) times more likely give low birth weight. Mothers who has no ANC visit was 4.49 times (AOR=4.49; 95%;CI; (1.38-14.55) times more likely delivered LBW infants.
Conclusion: The prevalence of low birth weight in the study area was comparatively lower than that of countrywide figure. Ethnicity, Family size, Nutritional status of the mother (low mid upper arm circumference), Antenatal visit and Carbohydrate rich food consumption score were the independent factors associated with low birth weight.
Based on the finite element method to analyse pull-out strength of round tenon joints in solid wood furniture
Authors: Quan Shuyan , Guo Minghui , Gao Xing 
Published: September 2022

Abstract
To prevent the problem of test chance in solid wood furniture joint strength testing and reduce the destructive test and test costs, the finite element method (FEM) and ABAQUS software were used to establish a cohesion model, which can predict the pull-out strength of L-shaped and T-shaped members using round tenon joints in the presence of adhesives. In addition, the effect of the diameter of the round tenon on the pull-out strength of the joints was investigated. The simulation results revealed that with the increase in the diameter, the pull-out strength of the double round tenon joint increased, indicating that the diameter of the round tenon is a key factor that affects the pull-out strength of joints. Furthermore, errors between the finite element analysis (FEA) results and the average test results of two members with different diameters were less than 15%, and the cloud diagrams of the structural stresses were consistent with the test results. Therefore, the established FEM is confirmed to be accurate and suitable for predicting the pull-out strength of designed round tenon joints in solid wood furniture. This paper provides new ideas and methods for the non-destructive testing of the structural-mechanical properties of solid wood furniture.
Comparison of the effects of emotionally focused therapy and transcranial direct current stimulation on anxiety and quality of life of patients with coronary artery disease during COVID-19 pandemic
Authors: Gili Shahnaz , Ebrahimiasl Sarieh 
Published: September 2022

Abstract
Background
The COVID-19 pandemic has increased psychological distress and impacted diagnosis and treatment of noncommunicable diseases. This study aimed to examine the comparative effectiveness of Emotionally Focused Therapy (EFT) and Transcranial Direct Current Stimulation (tDCS) on anxiety and quality of life in patients with coronary artery disease (CAD) during COVID-19 pandemic.
Methods
A total of forty-five participants who met criteria for a current episode of CAD chosen by convenience sampling method from Tehran city were randomly assigned to a 9-week/60-min EFT (n = 15) group therapy, 5-week/20-min tDCS (n = 15) experimental group and one control group (n = 15). They were assessed at pre-treatment, post-group, and 3-month follow-up. The study subjects completed the self-reported questionnaires, Beck Anxiety Inventory (BAI) and Health-Related Quality of Life (HRQOL).
Results
Repeated measures analysis of variance, ANOVA, was used to measure inferential statistics. There were significant improvements in Anxiety and Quality of Life scores in both EFT and tDCS groups over the post and follow-up period (P > 0.05). However, difference was found when EFT had a greater effect on Anxiety and Quality of Life.
Conclusions
These results showed EFT and tDCS have effective interventions in reducing anxiety and improving the quality of life of CAD patients, but improvements with EFT were greater than those with tDCS.
Comparative study on the behavior of keyhole in analogy welding and real deep penetration laser welding
Authors: Hao Zhongjia , Chen Huiyang , Jin Xiangzhong , Liu Zuguo 
Published: September 2022

Abstract
In deep penetration laser welding, the behavior of keyhole has an important influence on the welding quality. As it is difficult to directly observe the keyhole during metal laser welding, theoretical analysis and numerical simulation methods are common-used methods in studying the keyhole behavior, which cannot provide the direct real information of the keyhole behavior. In this paper, a method of analogy welding is proposed, in which high speed gas is used to blow the liquid to generate keyhole. Relevant process experiments are conducted to explore the keyhole behavior in the analogy welding and real deep penetration laser welding. The pressure balance of keyhole both in analogy welding and real deep penetration laser welding are analyzed. The laws obtained in analogy welding and real deep penetration laser welding are similar, which indicates that studying the keyhole formation and maintenance principle using the analogy welding method proposed in this paper may be helpful to deeply understand the keyhole formation and maintenance mechanism in real deep penetration laser welding.
Serum and Tissue Granulysin as a Possible Key Markers to Detect the Severity of Psoriasis
Authors: Gaber Hisham Diab , Bakr Radwa M. , ElMelegy Tarek Taha , Ahmed Yasmin Sayed , Gaber Reham M. Abdel 
Published: September 2022

Abstract
Background: Psoriasis is a chronic immune-mediated inflammatory skin disease, it is a disorder of both the innate and adaptive immune system. However, new updates are still emerging in its pathogenesis. Psoriasis is characterized by overexpression of antimicrobial peptides. Granulysin (GNLY) is an antimicrobial peptide that may have a role in psoriasis pathogenesis.
Objective: To detect the level of serum and tissue (GNLY) in psoriatic patients and correlate it with psoriasis severity.
Patients and Methods: The study was performed on 50 individuals, including 2 groups. The first group included 30 psoriasis vulgaris patients and the second group included 20 age and sex matched apparently healthy control individuals. Serum GNLY was determined in all individuals and tissue GNLY was determined in the skin of 8 patients (from lesional and perilesional skin) and 8 controls.
Results: serum GNLY was slightly higher in patients group compared to control group with no statistically significant difference while, the level of tissue GNLY of lesional and perilesional skin in psoriatic patients, was significantly higher when compared to control group.
Conclusion: In conclusion, granulysin is supposed to play a role in psoriasis pathogenesis and it is positively correlated with psoriasis severity
Gametocytogenesis-enhancing drug combinations can facilitate artemisinin resistance despite better clinical outcomes
Authors: Schneider Kristan , Kamanga George , Verma Kanika , Verma Anil , Bharti Praveen Kumar 
Published: September 2022

Abstract
Background: Malaria eradication goals are threatened by the spread of artemisinin resistance, which is an evolutionary process. The selective advantage of mutations in Plasmodium falciparum conferring tolerance or even resistance is determined as the probability of their successful transmission. The drug’s efficacy in clearing merozoites is the main determinant for the clinical pathogenesis, but only one of many factors determining successful transmission. The actual steps in the transmission cycles contribute as “fitness components”. The abundance of gametocytes is crucial in mediating how the selective advantage at the merozoite level is translated into evolutionary fitness. In this context it is important to recognize that some drugs are associated with higher gametocytaemia.
Method: A mechanistic model, which quantitatively describes how evolutionary fitness is determined by the parasite's life history in interaction with antimalarial drugs is formulated. The hypothetical effect of a gametocytogenesis-enhancing drug action on the evolutionary fitness is included. Once fitness is determined, an evolutionary-genetic model is used to describe the resulting trajectory of drug resistance evolution.
Results: Assuming intuitive model parameters, the evolutionary fitness of two alternative drug treatments with the same effectiveness on asexual parasites, with and without a gametocytogenesis-enhancing effect are contrasted. The gametocytogenesis-enhancing effect leads to a substantially faster spread of drug resistance. This result changes quantitatively, but not qualitatively, if a threshold gametocytaemia is assumed for successful malaria transmission. Isolating infections in quarantine in order to prevent transmission, can substantially accelerate the dispersion of resistance if antimalarials delay gametocyte development.
Conclusions: Gametocytogenesis-enhancing drug treatments can excel the spread of resistance. Initially it might appear that such a treatment leads to improved clinical outcomes, because drug resistance is difficult to detect on a population-level as long as resistance-conferring mutations have low prevalence. Hence, partnering artemisinin with drugs such as sulfadoxine-pyrimethamine of amodiaquine, which have been associated with higher gametocytaemia, might facilitate the spread of resistance.
Usability Evaluation Factors for Measuring an Accessible Mobile E-Book Applications for Visually Impaired
Authors: Matraf Munya Saleh Ba , Hashim Nor Laily , Hussain Azham 
Published: September 2022

Abstract
The emergence of e-books opens new opportunities for the visually impaired to overcome reading struggling. However, current mobile e-book applications are still not reaching their satisfactory level because of the limitations of mobile devices and lack of understanding of visually impaired needs among mobile application developers. Besides, important factors involve in usability evaluation studies for these applications are still unclear. Therefore, this study aims to develop a usability evaluation model to evaluate an accessible mobile e-book application for the visually impaired. Hence, the study conducted a literature review to identify the usability factors. Secondly, identify the factors that are most frequently used. The authors summarised the identified factors to develop the most important factors relevant to e-book applications for the visually impaired. Thirdly, these factors were then verified by eleven experts. In total, 36 factors were identified from the first phase. The study proposed only five factors: efficiency, effectiveness, satisfaction, learnability, and visual impaired accessibility after applying the summarization and simplifying methods. The results from the expert review shows that all experts agreed with the proposed factors as all the factors get a high average of at least four out of five. These identified factors are vitally important elements to be considered by mobile e-book developers and designers in evaluating whether their mobile e-book applications are usable and accessible to the visually impaired. Consequently, the visually impaired users of mobile e-book application will have the same chance as sighted to benefits from e-book applications.
Mental Health, Academic Stress, And Coping Strategy Among College Students
Authors: Hasanah Uswatun , Oktaviani Maya , Elmanora Elmanora , Zulfa Vania , Mulyati Mulyati , Kabbaro Hurriyyatun 
Published: September 2022

Abstract
Purpose: This study aimed to analyze students' mental health, academic stress, and coping strategies. This study uses an associative quantitative approach with a survey method. The population in this study were all students at the Universitas Negeri Jakarta who took part in online learning during lectures.
Materials and Methods: The sample was selected using a disproportionate random sampling technique. The sample used in this study was 675 active students (female = 544, male = 131) at the Universitas Negeri Jakarta. Mental health, academic stress, and student coping strategies were measured using the Depression Anxiety Stress Scale (DASS-21), Educational Stress Scale for Adolescents (ESSA-16), and modified Academic Coping Strategies Scale (ACSC) instruments, respectively. Test the validity and reliability of the data to fit with the model. Data analysis used multiple linear regression and partial correlation.
Results: The results showed that: (1) there were differences in mental health and academic stress between female and male students; (2) there were differences in coping strategies between students who were only children and middle children; (3) academic stress and coping strategies significantly affected students' mental health by 24.7%; (4) academic stress and coping strategies significantly influence students' mental health.
Conclusion: Academic stress is negatively related to mental health, while coping strategies are positively related to mental health.
Absorbable Clips Applied in Thoracoscopic Anatomical Lung Resection in Younger Children: A Retrospective Study
Authors: He Taozhen , Sun Xiaoyan , Luo Dengke , Dai Shiyi , Yuan Miao , Yang Gang , Cheng Kaisheng , Xu Chang 
Published: September 2022

Abstract
Objectives: This study aims to evaluate the feasibility and safety of a 5-mm absorbable clips applied in Thoracoscopic anatomical lung resection in younger children.
Methods: Demographic data and intra- and postoperative parameters of the two groups (Abs-o-lock group and Hem-o-lok group) were reviewed. In the Abs-o-lock group, 5-mm absorbable clips were used in TALR on all patients from January 2020 to March 2021. In the Hem-o-lok group, 5-mm Hem-o-lok clips were used from January to December 2019. The primary outcomes were the one-time success rate of ligation, major bleeding rate, conversion rate, dislodgement rate and operative time, which were compared between the two groups.
Results: There were 224 patients involved in this study, of whom 103 were in the Abs-o-lock group and 121 were in the Hem-o-lok group. The one-time success rate of ligation was 96.5% in the Abs-o-lock group and 98.9% in the Hem-o-lok group (p<0.05). No major bleeding occurred in either group. The conversion rates of the two groups were not significantly different (0/103 versus 2/121, p=0.55). The dislodgement rate did not significantly differ between the two groups (p=1.0). The operative time consumed in the Abs-o-lock group was much longer than that in the Hem-o-lok group in terms of subgroups of RES (resection of extralobar sequestration, p<0.05), lobectomy (p<0.05) and segmentectomy (p<0.05).
Conclusions: Compared to Hem-o-lok clips, it is feasible and safe to apply 5-mm absorbable clips for vessel sealing during thoracoscopic anatomical lung resection in younger children.