bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differential analysis of ergosterol function in response to high salt and sugar stress in Zygosaccharomyces rouxii
Authors: Song Na , Xia Huili , Yang Qiao , Zhang Xiaoling , Yao Lan , Yang Shihui , Chen Xiong , Dai Jun 
Published: August 2022

Abstract
Zygosaccharomyces rouxii is an osmotolerant and halotolerant yeast that can participate in fermentation. To understand the mechanisms of salt and sugar tolerance, the transcription levels of Z. rouxii M 2013310 under 180 g/L NaCl stress and 600 g/L glucose stress were measured. The transcriptome analysis showed that 2227 differentially expressed genes (DEGs) were identified under 180 g/L NaCl stress, 1530 DEGs were identified under 600 g/L glucose stress, and 1278 DEGs were identified under both stress conditions. Then, KEGG enrichment analyses of these genes indicated that 53.3% of the upregulated genes were involved in the ergosterol synthesis pathway. Subsequently, quantitative PCR was used to verify the results, which showed that the genes of the ergosterol synthesis pathway were significantly upregulated under 180 g/L NaCl stress. Finally, further quantitative testing of ergosterol and spotting assays revealed that Z. rouxii M 2013310 increased the amount of ergosterol in response to high salt stress. These results highlighted the functional differences in ergosterol under sugar stress and salt stress, which contributes to our understanding of the tolerance mechanisms of salt and sugar in Z. rouxii.
The Ambiguities of Being Stateless: Property Rights, Statelessness and Enemy Aliens in the United Kingdom, France, Belgium and Germany, 1914–1930
Authors: La Lumia Cristiano 
Published: August 2022

Abstract
By retracing the fate of stateless people of German origin, mainly former Reich citizens, who suffered persecution as enemy aliens during the First World War and in the 1920s, the article examines the ambiguities of stateless status in terms of enjoyment of civil rights and national inclusion (and exclusion). In particular, the essay highlights how statelessness was a resource for many stateless persons of German origin to protect their property rights in administrative and judicial proceedings in the Entente countries, mainly to free their seized assets. Their story was an example of the multifaceted nature of statelessness in postwar Europe. The article focuses on the issue of the recognition of their status in Western Europe—particularly Belgium, France and the United Kingdom—in order to show the variety of criteria that guided the choices of governments and courts. In several national and imperial contexts, there was a tension between the judicial and executive powers that raised issues of sovereignty and rule of law in postwar democracies. Finally, the essay analyses the relationship between stateless persons of German origin and the Weimar Republic. On many occasions, the German state offered its diplomatic and financial support to enable those former citizens to recover their property. By analysing the diplomatic efforts and the provisions on compensation, the article points out the ambiguity around national and legal belonging to the German nation.
Does Higher Worker Retention Buffer Against Consumer Complaints? Evidence From Ohio Nursing Homes
Authors: Kennedy Katherine A , Bowblis John R 
Published: August 2022

Abstract

Background and Objectives
This study examined the relationship between nursing home (NH) quality using consumer complaints and certified nursing assistant (CNA) annual retention rates among Ohio freestanding NHs (n = 691).

Research Design and Methods
Core variables came from the 2017 Ohio Biennial Survey of Long-term Care Facilities and Centers for Medicare and Medicaid Services Automated Survey Processing Environment Complaints/Incidents Tracking System. To compare NHs, 4 quartiles of CNA retention rates were created: low (0%–48%), medium (49%–60%), high (61%–72%), and very high retention (73%–100%). Negative binomial regressions were estimated on total, substantiated, and unsubstantiated allegations and complaints. All regressions controlled for facility and county-level factors and clustered facilities by county.

Results
NHs in the top 50% (high and very high) of retention received 1.92 fewer allegations than those in the bottom 50%, representing a 19% difference; this trend was significant and negative across all outcomes. Using quartiles revealed a nonlinear pattern: high-retention NHs received the fewest number of allegations and complaints. The differences between high and low retention on allegations, substantiated, and unsubstantied allegations were 33% (3.73 fewer), 34% (0.51 fewer), and 32% (3.12 fewer), respectively. Unexpectedly, very high-retention NHs received more unsubstantiated allegations than high-retention NHs.

Discussion and Implications
While higher-retention should result in fewer complaints, our results indicate that some turnover may be desirable because the very high-retention NHs performed slightly worse than those with high retention. Among the remaining facilities, fewer complaints may be achieved by improving CNA retention through higher wages, career advancement, and better training.
Eikonal surface wave tomography of central and eastern China
Authors: Zhou Pengxiang , Chevrot Sébastien , Lehujeur Maximilien , Xia Shaohong , Yu Chunquan 
Published: August 2022

SUMMARYEikonal tomography has become a key approach to image lithospheric structures with surface waves recorded by dense regional arrays. Its main advantage is that phase velocities can be determined directly from phase measurements without resolving a tomographic inverse problem. Here, we apply a new smoothing spline eikonal tomography approach to a selection of 40 large (Mw larger than 6.5) teleseismic events recorded by the permanent seismic stations of the CEArray. We first apply a time–frequency filter to isolate the fundamental mode of Rayleigh waves and cross-correlate the cleaned and isolated surface wave records to measure precise relative traveltimes. The phase measurements are then unwrapped and corrected for cycle skipping. Finally, we derive phase-velocity maps from the gradient of the reconstructed traveltime fields, using the eikonal equation. We obtain finely resolved phase-velocity maps from 25 to 150 s period that are inverted to obtain a 3-D shear wave velocity model which is in good agreement with previous tomographic studies. The lithospheric architecture emerging from the phase-velocity maps and 3-D S-wave velocities correlates with surface geology and major tectonic provinces. In particular, the architecture of the narrow rift systems, the South China Craton, and the North China Craton (NCC) are revealed with unprecedented details. The South China Craton is characterized by very high velocities beneath the Sichuan Basin. The NCC shows more complex structures with two high-velocity anomalies beneath the Ordos Basin and the southeastern NCC and low-velocity anomalies beneath the Cenozoic rift systems.
Target-enclosing inversion using an interferometric objective function
Authors: Zheglova Polina , Ravasi Matteo , Vasconcelos Ivan , Malcolm Alison 
Published: August 2022

SUMMARY
Full waveform inversion is a high-resolution subsurface imaging technique, in which full seismic waveforms are used to infer subsurface physical properties. We present a novel, target-enclosing, full-waveform inversion framework based on an interferometric objective function. This objective function exploits the equivalence between the convolution and correlation representation formulas, using data from a closed boundary around the target area of interest. Because such equivalence is violated when the knowledge of the enclosed medium is incorrect, we propose to minimize the mismatch between the wavefields independently reconstructed by the two representation formulas. The proposed method requires only kinematic knowledge of the subsurface model, specifically the overburden for redatuming and does not require prior knowledge of the model below the target area. In this sense it is truly local: sensitive only to the medium parameters within the chosen target, with no assumptions about the medium or scattering regime outside the target. We present the theoretical framework and derive the gradient of the new objective function via the adjoint-state method and apply it to a synthetic example with exactly redatumed wavefields. A comparison with FWI of surface data and target-oriented FWI based on the convolution representation theorem only shows the superiority of our method both in terms of the quality of target recovery and reduction in computational cost.
Seismic wave propagation simulations in Indo-Gangetic basin using spectral element method
Authors: Sreejaya K P , Raghukanth S T G , Srinagesh D 
Published: August 2022

SUMMARY
This study focuses on developing a 3-D computational model of the Indo-Gangetic basin (IG basin) using the spectral element method. The region includes the subcontinent's most densely populated areas. The basin is unique as it consists of geologically younger sedimentary layers along with several ridges and depressions in its domain. However, the proximity of great Himalayan earthquakes and the presence of thick sedimentary layers of the basin results in higher seismic hazards. The limited instrumentation of the domain poses challenges in understanding the response of the basin due to a seismic event. This motivated us to develop a computational model of the IG basin by incorporating the best-known geometry, material properties and fine resolution topography. In the lateral direction, the modelled part of IG basin spans over ∼6° × 4° (between longitude 80.5°–86.5°E and latitude 25°–29°N). The validation of the developed basin model is performed by simulating the ground motions for the 2015 Mw 7.9 Nepal main shock and five of its aftershocks. Both qualitative and quantitative comparison of the simulated time histories suggests that the developed model could accurately simulate ground motions over a frequency range of 0.02–0.5 Hz. The developed basin model is then used to understand the seismic wavefield characteristics during the 2015 Mw 7.9 Nepal main shock. The spatial variation of peak ground velocity (PGV), as well as amplification, are investigated at a 0.2° × 0.2° grid and selected cities in the basin. The contours of PGV amplification indicate a higher value of ∼8–10 in the horizontal direction and ∼2.5–3.5 in the vertical direction for sediment depth &gt;4 km. A comprehensive comparison of the simulated PGVs and the ground motion prediction equations shows that, while the simulations agree with the prediction, they also show heterogeneity of ground-motion distribution that cannot be fully described by empirical prediction relations. Hence the results from this study are more reliable and find applications in seismic hazard assessment of the cities in the basin. Besides, the results can be used to guide the installation of future seismic stations in the region.
Kathmandu Basin as a local modulator of seismic waves: 2-D modelling of non-linear site response under obliquely incident waves
Authors: Oral Elif , Ayoubi Peyman , Ampuero Jean Paul , Asimaki Domniki , Bonilla Luis Fabian 
Published: August 2022

SUMMARYThe 2015 Mw 7.8 Gorkha, Nepal earthquake is the largest event to have struck the capital city of Kathmandu in recent times. One of its surprising features was the frequency content of the recorded ground motion, exhibiting a notable amplification at low frequencies (&lt;2 Hz) and a contrasting depletion at higher frequencies. The latter has been partially attributed to the damper behaviour of the Kathmandu basin. While such weak high-frequency ground motion helped avoiding severe damage in the city, the catastrophic outcomes of earlier earthquakes in the region attest to a contrasting role of the Kathmandu basin as a broad-band amplifier, in addition to possible source effects. Given the possibility of future strong events in the region, our main objective is to elucidate the seismic behaviour of the Kathmandu basin by focusing on site effects. We numerically model 2-D P–SV wave propagation in a broad frequency band (up to 10 Hz), incorporating the most recent data for the Kathmandu basin geometry, soil stratigraphy and geotechnical soil properties, and accounting for the non-linear effect of multidimensional soil plasticity on wave propagation. We find that: (1) the Kathmandu basin generally amplifies low frequency ground motion (&lt;2 Hz); (2) waves with large incidence angles relative to vertical can dramatically amplify the high frequency ground motion with respect to bedrock despite the damping effect of soil non-linearity and (3) the spatial distribution of peak ground motion amplitudes along the basin is highly sensitive to soil non-linearity and wave incidence (angle and direction), favouring larger values near the basin edges located closer to the source, as observed during the 2015 event. Our modelling approach and findings can support the ongoing resilience practices in Nepal and can guide future seismic hazard assessment studies for other sites that feature similar complexities in basin geometry, soil stratigraphy and dynamic soil behaviour.
Go west: Contextualizing Scandinavian royal naval expeditions into the Insular world, 1013–1103
Authors: Ellis Caitlin 
Published: August 2022

Abstract
Scholarly attention has focused on the explanation for raids at the start of the ‘Viking Age’, not on the motivations for royal expeditions of the eleventh century. This article examines Sven and Cnut’s invasion of England, the Norwegian prince Magnus Haraldsson’s presence in the Insular world, Harald harðráði’s attempted invasion of England, a series of failed Danish interventions in England, and Magnus Barelegs’s expeditions to Orkney and the Irish Sea region. It argues that Scandinavian kings and princes capitalized on political weaknesses in the Insular world, but their expansionist ambitions were often hampered by internal conditions in their own kingdoms.
Too much can be as bad as too little: product update strategy for online digital platform complementors
Authors: Kang Hye Young 
Published: August 2022

AbstractProduct updates have become prevalent on online digital platforms, given the unique market, product, and technological characteristics that underlie digital platforms. Scholars have begun to explore the efficacy of updates on digital platforms, highlighting the merits of implementing frequent updates. Drawing on behavioral decision theory, this paper analyzes the trade-offs that consumers encounter between the benefits and costs associated with updates and challenges an implicit assumption held in extant studies with respect to the linear efficacy of updates. In the context of mobile platforms, this paper, using a multi-method study, identifies the existence of an inverted U-shaped relationship between product updates and complementor product performance. We also find that the moderating efficacy of platform endorsement is positive in that it serves as an amplifier of whatever a complementor offers, tightly intertwined with the complementor’s offerings. Our paper expands the platform literature by investigating successful complementor product strategies that take into account unique platform characteristics with a strong grounding in interdependent owner–complementor dynamics.
Influence of near bottom fish distribution on the efficacy of a combined hydroacoustic video survey
Authors: Rasmuson Leif K , Marion Scott R , Fields Stephanie A , Blume Matthew T O , Lawrence Kelly A , Rankin Polly S 
Published: August 2022

Abstract
Combining hydroacoustics and underwater video is an effective tool for generating fish population estimates. However, hydroacoustics cannot be used to differentiate fish from the seafloor within an area known as the acoustic dead zone. A common way to address this is to exclude data near the bottom. The effect of this exclusion zone on population estimates of nearshore semi-pelagic rockfish is unknown. This study explores the effect of a near bottom (0–1 m) exclusion zone by comparing ROV video data to data from a combined hydroacoustic and video method. Higher densities of semi-pelagic species (Black and Blue/Deacon Rockfish) were observed in the combined acoustic and video method, suggesting that most of the population resides above the exclusion zone. Demersal rockfish observed by the ROV did not contaminate acoustic data of semi-pelagic species, since they remained within the exclusion zone. Results demonstrate that extrapolation of school data into the exclusion zone provided a realistic correction to the acoustic data for Black Rockfish. Our work demonstrates that excluding the data within 1 m of the bottom does not negatively affect the ability of the combined video hydroacoustic method to sample semi-pelagic rockfish.
Mood Stabilizers and Antipsychotics for Acute Mania: Systematic Review and Meta-Analysis of Augmentation Therapy vs Monotherapy From the Perspective of Time to the Onset of Treatment Effects
Authors: Tajika Aran , Hori Hikaru , Iga Jun-ichi , Koshikawa Yosuke , Ogata Haruhiko , Ogawa Yusuke , Watanabe Koichiro , Kato Tadafumi , Matsuo Koji , Kato Masaki 
Published: August 2022

Abstract

Background
Existing meta-analytic evidence on bipolar mania treatment has revealed that augmentation therapy (AUG) with antipsychotics and mood stabilizers is more effective than monotherapy. However, the speed of the onset of treatment effects and subsequent changes in risk/benefit are unclear.

Methods
We searched the Cochrane CENTRAL, MEDLINE, and EMBASE databases until January 2021. Our primary outcomes were response and tolerability. We set 3 time points: 1, 3, and 6 weeks after randomization.

Results
Seventeen studies compared AUG therapy and MS monotherapy (comparison 1), and 8 studies compared AUG therapy and antipsychotics monotherapy (comparison 2). In comparison 1, AUG therapy resulted in significantly more responses than monotherapy, with an odds ratio of 1.45 (95% confidence interval [CI]: 1.17 to 1.80) at 3 weeks and 1.59 (95% CI: 1.28 to 1.99) at 6 weeks. Significant improvement was observed in the first week with a standardized mean difference of −0.25 (95% CI: −0.38 to −0.12). In comparison 2, AUG therapy was significantly more effective than monotherapy, with an odds ratio of 1.73 (95% CI: 1.25 to 2.40) at 3 weeks and 1.74 (95% CI: 1.11 to 2.73) at 6 weeks. Significant improvement was observed in the first week with an standardized mean difference of −0.23 (95% CI: −0.39 to −0.07). Regarding tolerability, there was no significant difference between AUG therapy and monotherapy at 3 and 6 weeks in both comparisons.

Conclusions
Early AUG therapy should be considered, as it has shown efficacy from weeks 1 to 6, although attention to side effects is necessary for acute mania treatment.
Impunity and Transitional Justice in Indonesia: Aksi Kamisan’s Circular Time
Authors: Drexler Elizabeth F 
Published: August 2022

ABSTRACT∞
This article positions the Indonesian weekly Thursday silent protests by victims’ families, Aksi Kamisan, as a space of and beyond transitional justice. Analysing Kamisan as repeated, embodied creative acts that reset perceptions, possibilities and imaginations about social belonging, political subjectivity and national identity discloses how authoritarian era affective forces undermine transitional justice and demonstrates the power of alternative temporalities in coming to terms with past violence. ‘Circular time’ brings past and present injustice into the same frame as consistent action extending into the future. Circular time highlights how the time of waiting, uncertainty and lack of justice extends backward and forward connecting past, present and future in the repetition of impunity, and creates community and the space to imagine just futures. Circular time is created by repeated action against impunity in the present and celebrating the perseverance, consistency and agency of victims. Circular time resists the imposition of temporal linearity. Art performed at Kamisan and the act of standing in solidarity engages communities and audiences in a realm of politics and national belonging that is not possible in formal institutions. Over time, these repeated, temporary, inclusive actions can counter still resonant authoritarian era propaganda.
Optimal recovery of precision matrix for Mahalanobis distance from high-dimensional noisy observations in manifold learning
Authors: Gavish Matan , Su Pei-Chun , Talmon Ronen , Wu Hau-Tieng 
Published: August 2022

Abstract
Motivated by establishing theoretical foundations for various manifold learning algorithms, we study the problem of Mahalanobis distance (MD) and the associated precision matrix estimation from high-dimensional noisy data. By relying on recent transformative results in covariance matrix estimation, we demonstrate the sensitivity of MD and the associated precision matrix to measurement noise, determining the exact asymptotic signal-to-noise ratio at which MD fails, and quantifying its performance otherwise. In addition, for an appropriate loss function, we propose an asymptotically optimal shrinker, which is shown to be beneficial over the classical implementation of the MD, both analytically and in simulations. The result is extended to the manifold setup, where the nonlinear interaction between curvature and high-dimensional noise is taken care of. The developed solution is applied to study a multi-scale reduction problem in the dynamical system analysis.
Optimal orthogonal group synchronization and rotation group synchronization
Authors: Gao Chao , Zhang Anderson Y 
Published: August 2022

Abstract
We study the statistical estimation problem of orthogonal group synchronization and rotation group synchronization. The model is $Y_{ij} = Z_i^* Z_j^{*T} + \sigma W_{ij}\in{\mathbb{R}}^{d\times d}$ where $W_{ij}$ is a Gaussian random matrix and $Z_i^*$ is either an orthogonal matrix or a rotation matrix, and each $Y_{ij}$ is observed independently with probability $p$. We analyze an iterative polar decomposition algorithm for the estimation of $Z^*$ and show it has an error of $(1+o(1))\frac{\sigma ^2 d(d-1)}{2np}$ when initialized by spectral methods. A matching minimax lower bound is further established that leads to the optimality of the proposed algorithm as it achieves the exact minimax risk.
Enhanced Severe Acute Respiratory Syndrome Coronavirus 2 Antigen–Specific Systemic Immune Responses in Multisystem Inflammatory Syndrome in Children and Reversal After Recovery
Authors: Kumar Nathella Pavan , Venkataraman Aishwarya , Nancy Arul , Moideen Kadar , Varadarjan Poovazhagi , Selladurai Elilarasi , Sangaralingam Thankgavelu , Selvam Ramya , Thimmaiah Akshith , Natarajan Suresh , Ramasamy Ganesh , Hissar Syed , Radayam Ranganathan Umadevi , Babu Subash 
Published: August 2022

Abstract

Background
Multisystem inflammatory syndrome in children (MIS-C) presents with inflammation and pathology of multiple organs in the pediatric population in the weeks following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

Methods
We characterized the SARS-CoV-2 antigen–specific cytokine and chemokine responses in children with MIS-C, coronavirus disease 2019 (COVID-19), and other infectious diseases.

Results
MIS-C is characterized by elevated levels of type 1 (interferon-γ, interleukin [IL] 2), type 2 (IL-4, IL-13), type 17 (IL-17), and other proinflammatory cytokines (IL-1α, IL-6, IL-12p70, IL-18, and granulocyte-macrophage colony-stimulating factor) in comparison to COVID-19 and other infectious diseases following stimulation with SARS-CoV-2–specific antigens. Similarly, upon SARS-CoV-2 antigen stimulation, CCL2, CCL3, and CXCL10 chemokines were significantly elevated in children with MIS-C in comparison to the other 2 groups. Principal component analysis based on these cytokines and chemokines could clearly distinguish MIS-C from both COVID-19 and other infections. In addition, these responses were significantly diminished and normalized 6–9 months after recovery.

Conclusions
Our data suggest that MIS-C is characterized by an enhanced production of cytokines and chemokines that may be associated with disease pathogenesis.