bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neurological Involvement in Multisystem Inflammatory Syndrome in Children: Clinical, Electroencephalographic and Magnetic Resonance Imaging Peculiarities and Therapeutic Implications. An Italian Single-Center Experience
Authors: Bova Stefania Maria , Serafini Ludovica , Capetti Pietro , Dallapiccola Andrea Riccardo , Doneda Chiara , Gadda Arianna , Lonoce Luisa , Vittorini Alessandra , Mannarino Savina , Veggiotti Pierangelo ,   Milan MIS-C Study Group
Published: August 2022

ObjectiveTo describe neurological involvement in multisystem inflammatory syndrome in children (MIS-C) and to evaluate whether neurological manifestations are related to the degree of multiorgan involvement and inflammation.MethodsThe authors conducted a retrospective analysis of clinical, electroencephalographic (EEG), neuroradiological (MRI), and CSF parameters in 62 children with MIS-C (45 M, age 8 months—17 years, mean age 9 years) hospitalized between October 1, 2020 and March 31, 2022.ResultsNeurological involvement was documented in 58/62 (93.5%) patients. Altered mental status was observed in 29 (46.7%), focal neurological signs in 22 (35.4%), and non-specific symptoms in 54 (87%). EEG was performed in 26/62 children: 20 showed EEG slowing, diffuse or predominantly over the posterior regions. Ten patients underwent brain MRI: three showed a cytotoxic lesion of the corpus callosum. CSF analysis, performed in six patients, was normal. On the basis of the clinical and EEG findings, two profiles of neurological involvement were identified: 16/62 (26%) patients presented encephalitis with rapid-onset encephalopathy, focal neurological signs, and EEG slowing; 42/62 (68%) showed mild neurological involvement with mild or non-specific neurological signs. All patients received intravenous immunoglobulin and methylprednisolone (MTP), low-molecular-weight heparin, and therapeutic-dose anticoagulant treatment. Children with severe encephalopathy received intravenous MTP at 30 mg/kg/day for 3 days, obtaining rapid clinical and EEG improvement. Neurological assessment at discharge was normal in all cases. Children with encephalitis were younger than those without (median age 5 and 10 years, respectively); no differences between the two groups were found in the other parameters: comorbidities, fever, number of organs and systems involved, shock, hospitalization, pediatric intensive care unit admission, non-invasive ventilation, inotropic support, laboratory data.ConclusionNeurological involvement in MIS-C is frequent but not serious in most cases: around two thirds of the affected children had mild and short-lasting symptoms. It seems to be related to age, but not to the degree of multiorgan involvement and inflammation. In children with acute immune-mediated encephalitis, the clinical picture was dominated by encephalopathy that disappeared with immunomodulatory therapy. Neurological assessment allowed timely diagnosis and treatment.
Implementation of early rehabilitation for critically ill children in China: A survey and narrative review of the literature
Authors: Zhang Ting , Duan Xiaoling , Feng Ying , Jiang Wei , Hou Xueqin , Liu Ling , Huang Qinrong , Tang Xiang , Lin Li , Zhang Mingqiang , Tao Liang , Liu Guoqing , Chen Yuxia , Xiao Nong 
Published: August 2022

IntroductionThe focus of this survey was to understand the current status of implementation of early rehabilitation for critically ill children in China. We also reviewed the available literature on this topic for further insights to inform its future development.Materials and methodsWe used a cross-sectional study design to survey tertiary hospitals nationwide. Questionnaires were distributed via the social media platform “WeChat Questionnaire Star” within the framework of the Rehabilitation Group of the Pediatrics Branch of the Chinese Medical Association. A narrative literature review on the implementation of the early rehabilitation for critically ill pediatric and/or adult patients was carried out.ResultsA total of 202 valid questionnaires were received. About half (n = 105, 52.0%) of respondent hospitals reported that they implement early rehabilitation for critically ill children. Among these 105 hospitals, 28 implemented a continuous chain of early rehabilitation. A total of 24 hospitals had set up permanent specialized centralized early rehabilitation units for critically ill children.Implications and future directionsEarly rehabilitation for critically ill children is not widely available in China and only a minority of hospitals implement a continuous chain of early rehabilitation. To improve this undesirable situation, we suggest creating a two-level integrated system comprising centralized early rehabilitation units and surrounding early rehabilitation networks within a region.
Modulation of neuromuscular excitability in response to acute noxious heat exposure has no additional effects on central and peripheral fatigability
Authors: Eimantas Nerijus , Ivanove Soneta , Baranauskiene Neringa , Solianik Rima , Brazaitis Marius 
Published: August 2022

Background: Whole-body hyperthermia (WBH) has an adverse effect on the nervous system and neurophysiological performance. In the present study, we examined whether short-duration whole-body immersion in 45°C water (HWI-45°C), which produces a strong neural and temperature flux without inducing WBH, can increase or impair neurophysiological performance in humans.Methods: Fifteen men (aged 25 ± 6 years) were enrolled in this study and participated in three experiments: 1) a brief (5-min) immersion of the whole body in 37°C water (WI-37°C); 2) a brief (5-min) HWI-45°C; and 3) a control trial in a thermoneutral condition at an ambient temperature of 24°C and 60% relative humidity. Before and after the immersions, neuromuscular function (electromyographic activity, reflexes, electrically and voluntary induced torque production, voluntary muscle activation level) were tested. To provoke central inhibition, the participants performed a sustained 2-min maximal voluntary contraction (MVC).Results: Thermophysiological strain was greater after HWI-45°C than after WI-37°C. Electrophysiological modulations of motor drive transmission and peripheral modulations of muscle contractility properties in response to HWI-45°C seemed to have little effect on central activation of the exercising muscles and no effect on MVC production.Conclusion: Although exposure to acute noxious heat was effective in evoking neuromuscular excitability, the increases in core temperature (∼0.2°C) and muscle temperature (∼0.6°C) did not induce moderate or severe WBH. These changes did not seem to affect central structures; that is, there were no additional increases in central and/or peripheral fatigue during a sustained 2-min MVC.
The relationship between childhood trauma and post-traumatic growth among college students: The role of acceptance and positive reappraisal
Authors: Quan Lijuan , Lü Bijun , Sun Jialei , Zhao Xintong , Sang Qingsong 
Published: August 2022

ObjectiveTo examine the relationship among childhood trauma, acceptance, positive reappraisal and post-traumatic growth (PTG) among college students.MethodsResearch participants were selected by random cluster sampling. 1,028 college students (62.6% female, 30.5% only-children) from 8 universities were investigated using manuscript-pencil survey versions of Childhood Trauma Questionnaire-Short Form (CTQ-SF), Cognitive emotion regulation questionnaire–Chinese version (CERQ-C) and Post traumatic Growth Inventory (PTGI).ResultsTraumatic childhood experience significantly negatively predicts post traumatic growth in college students. Exposure to traumatic experiences in childhood can directly negatively predict post-traumatic growth and indirectly positively predict post traumatic growth via acceptance.ConclusionAcceptance plays a mediating role between childhood traumatic experience and post traumatic growth. The mediating effect of acceptance is moderated by the positive reappraisal. When individuals have a lower level of positive reappraisal, the mediating effect between traumatic experience and post traumatic growth is significant. Several clinical implications for clinical psychology and psychological intervention are highlighted. Starting with changing individual cognition and helping individuals adopt positive cognitive emotion regulation strategies can help individuals actively reevaluate traumatic experience, so as to gain better and faster counseling results.
The relationship between resilience, anxiety, and depression in Chinese collegiate athletes
Authors: Lyu Chengjie , Ma Rong , Hager Ronald , Porter Dave 
Published: August 2022

Anxiety disorder is becoming increasingly prevalent across college campuses, particularly among collegiate athletes who face different stressors and challenges than their non-athlete peers. Anxiety and depression are well documented comorbidities. Furthermore, the number of Chinese collegiate athletes suffering from anxiety and depression is increasing. Psychologists have recently begun to take a more prophylactic approach to defend against these disorders through resilience education. Resilience education focuses on developing greater capacity to cope when mental and emotional challenges arise. The purpose of this study was to analyze the relationship between resilience, depression, and anxiety in Chinese collegiate athletes. This study provides additional evidence of the value of incorporating an effective resilience educational module amongst collegiate athletes.Research designThe study employed a survey research design to explore the complex relationship between depression, anxiety, and resilience for collegiate student athletes.Data analysis strategyStructural Equation Modeling (SEM) was employed to account for any measurement error between the observed items (responses on the instruments) and the latent variables (anxiety, depression, and resilience). The theoretical hypothesized relationship for this study is an inverse relationship between anxiety and depression, on the one hand, and resilience on the other hand. The SEM statistical analysis from this study supported this theoretical model.Effective sample size599 collegiate athletes from six different universities in the province of Guangdong, China P.R. participated in this study.
Time management disposition and relevant factors among new nurses in Chinese tertiary hospitals: A cross-sectional study
Authors: Xie Jianfei , Wu Xiaoqi , Li Jie , Li Xiaolian , Xiao Panpan , Wang Sha , Zhong Zhuqing , Ding Siqing , Yan Jin , Li Lijun , Cheng Andy S. K. 
Published: August 2022

IntroductionNew nurses struggled with time management, which was a prominent theme in safety care for patients. However, the transition training of time management for new nurses was complicated and ignored by clinical managers. The purpose of this study was to understand the level of new nurses’ TMD from a nationwide perspective and detect the influencing factors of the TMD.Materials and methodsA cross-sectional study design with a stratified sampling method was sampled in China. Six hundred and seventy new nurses within the first year of employment were recruited. New nurses’ time management disposition, job stressors, self-efficacy, clinical communication competence, and safety behavior were measured by corresponding scales.ResultsNew nurses showed the best sense of time’s value, followed by the sense of time efficacy and time monitoring view for time management disposition. The related factors of time management disposition were communication skills, safety behavior, job stressors, and being without a preceptor. New nurses’ time management disposition was at a moderate level and they performed worse in time allocation. The highest education, with or without a preceptor, the experience of part-time jobs, and class cadre were significantly influencing the time management disposition of new nurses.ConclusionNursing managers should pay attention to new nurses’ time management disposition. Reducing the job stressors, improving communication ability, and safe behavior were important measures to improve the time management disposition.
Nutrition literacy and its related demographic factors among workers of Taraz Steel company, Chaharmahal and Bakhtiari, Iran
Authors: Yarmohammadi Parastoo , Morowatisharifabad Mohammad Ali , Rahaei Zohreh , Khayyatzadeh Sayyed Saeid , Madadizadeh Farzan 
Published: August 2022

BackgroundNutrition is critical to prevent some chronic diseases. Nutrition literacy refers to ability to gain, understand and evaluate nutrition facts to choose appropriate foods. Nutrition literacy has recently drawn the attention of professionals with respect to health promotion. The purpose of this study was to investigate nutrition literacy and potentially related demographic factors among workers of a steel company in Chaharmahal and Bakhtiari province, southwest Iran.MethodsIn this descriptive-analytical study in 141 workers of Taraz Steel company in 2021, participants were selected by convenience sampling and a self-report nutrition literacy scale nativized to Iranians was used to collect data. Data were analyzed by SPSS 22 using Mann-Whitney U test, Kruskal-Wallis test and Spearman's correlation coefficient.ResultsAbout 75% of workers had adequate nutrition literacy and around 24% inadequate nutrition literacy. The highest percentage of mean score was obtained for determination of food groups (85.4%) and the lowest for calculation of food units (47%). The mean score of nutrition literacy was significantly higher in people with higher education (P = 0.020). Also, people with adequate monthly salary attained a higher mean score on determination of food groups (P = 0.021) and higher overall nutrition literacy (P = 0.003) compared to other people. No relationship was observed between nutrition literacy and body mass index as well.ConclusionMost workers have adequate nutrition literacy but their scores on calculation of food units are relatively low. It is essential for policymakers to collect information on the level of nutrition literacy in different populations, especially Iranian workers, to reduce the prevalence of nutrition-related chronic diseases.
Identifying conditions for a third dose intention of COVID-19 vaccination in college students: A fuzzy-set qualitative comparative analysis
Authors: Gao Wanqin , Zhang Yulin , Yin Gang 
Published: August 2022

BackgroundDuring the pandemic, a third dose of the COVID-19 vaccine effectively reduces the proportion of severe cases in those infected, but vaccine hesitancy impedes this reasonable prevention method. Epidemic control in China is being tested due to the large population base, especially in crowded places like college campuses. This study aimed to explore the configuration paths of psychological antecedents for college students to receive a third COVID-19 vaccine.MethodsAn anonymous cross-sectional survey was carried out in five universities in Wuhan using convenience sampling. A long version of the 5C 7-point Likert scale was used to measure college students' intention and psychological antecedents on the third dose of the COVID-19 vaccine. A fuzzy-set Qualitative Comparative Analysis (QCA) approach was performed to explore the configuration of conditions to the vaccination willingness.Results31.67% of respondents surveyed did not receive their third dose of the COVID-19 vaccine. The score of intention to get the vaccine for college students who did not receive the booster vaccine was 4.93 (±1.68). Average scores of 5.19 (±1.24), 4.35 (±1.75), 4.02 (±1.45), 5.84 (±1.23), and 4.61(±1.32) were reported for confidence, complacency, constraints, calculation, and collective responsibility in them. QCA showed high confidence and collective responsibility playing a central role in third dose vaccination intention. Meanwhile, low confidence and collective responsibility are the core conditions of low vaccination willingness.ConclusionEliminating vaccine hesitancy necessitates focusing on the psychological antecedents of vaccination intentions to identify critical targets for policy and interventions. This study identified trust and collective responsibility are core elements of the psychological antecedents of college students' intention to receive the booster vaccine for COVID-19. To achieve herd immunity as soon as possible, health administration and campus can start with vaccine confidence-building and collective responsibility cultivation to take appropriate actions and measures to improve coverage of the booster vaccination.
Optimizing bowel preparation for colonoscopy: A cross-sectional study of the Chinese population
Authors: Luo Li , Liu Yuan , Zhang Lingling , Lai Yihuan , Li Yansheng , Liu Kejia , Gong Houwu , Jiang Dapeng , Wang Erchuan 
Published: August 2022

BackgroundThe quality of bowel preparation is an important factor in the success of colonoscopy. However, the quality of bowel preparation is often affected by multiple factors. The main objective of this study was to explore the specific factors that affect the quality of bowel preparation.MethodsPatients were consecutively recruited from the gastroenterology department in Union Hospital, Tongji Medical College, Huazhong University of Science and Technology in Wuhan from May 2018 to December 2018. All patients were undergoing colonoscopy. Bowel preparation was evaluated by the Ottawa Bowel preparation Scale (OBPS) and all patients were categorized into 2 groups according to the OBPS. Multivariate analysis was conducted to identify the factors associated with bowel preparation quality.ResultsA total of 910 patients were included in the analysis with an average age of 48.62 ± 13.57 years. Patient source (P &lt; 0.001) and the preparation method (P = 0.029) were correlated with OBPS adequacy. In addition, after stratified by age, preparation method (P = 0.022) was a significant factor among patients under 50 years old; whereas waiting time (P = 0.005) was a significant factor among patients over 50 years old.ConclusionBowel preparation should be tailored based on the age of the patients to determine the most appropriate plan, including the most appropriate waiting time and the most appropriate purgative combination. Doctors should also focus more on the quality of bowel preparation in inpatients, who are more likely than outpatients to have an inadequate bowel preparation.
PENGEMBANGAN MULTIMEDIA PENGENALAN SINGA UNTUK ANAK USIA DINI
Authors: Nabil Pratama Syahdan , Hidayat Bobby Rizki Nur , Mas Wildan Muhtar Alfian , Ramli Rizal , Latif Abdul , Robbani Faiz Jundi 
Published: August 2022

Penelitian ini bertujuan untuk mengembangkan multimedia pengenalan singa melalui Media Adobe Flash pada anak usia dini. Pengembangan multimedia pengenalan singa untuk anak usia dini dirancang sebagai media pembelajaran dengan memberikan materi yang dibalut dengan gambar animasi serta menyertakan soal sebagai bahan evaluasi pembelajaran. Hasil penelitian dapat dilihat dalam tabel evaluasi, dari 10 anak yang mengikuti pembelajaran.Semua anak mendapatkan nilai diatas batas minimal yaitu 6 Dengan demikian anak-anak tersebut dapat memahami materi yang disampaikan melalui media multimedia:
Media Pembelajaran Multimedia Interaktif Mengenai Pengenalan Nama Buah dalam Tiga Bahasa untuk Anak Usia Dini
Authors: Kaffah Salsabila Ayuni 
Published: August 2022

Perkembangan teknologi pada era sekarang terbilang begitu cepat. Hal tersebut dapat kita lihat pada perkembangan teknologi gawai pada saat ini, dimana perangkat mobile/ desktop saat ini tidak hanya digunakan sebagai alat untuk berkomunikasi, namun juga mampu digunakan sebagai salah satu media edukasi/pembelajaran. Salah satu yang dinilai memiliki peranan cukup besar dalam dunia edukasi saat ini merupakan game edukasi. Pemanfaatan teknologi game jenis ini yang digunakan sebagai penunjang materi dalam proses belajar mengajar anak dinilai sebagai salah satu cara yang tepat, karena Game edukasi sebagai media visual mempunyai keunggulan lebih apabila dibandingkan dengan media visual yang lain seperti buku atau e-book.Tujuan dari penelitian ini sendiri yakni untuk membuat atau mengembangkan sebuah aplikasi mobile/desktop bertipe game edukasi sebagai media penunjang edukasi/pembelajaran dalam hal ini yakni : mengenal nama buah dalam 3 bahasa berbeda termasuk Bahasa Indonesia , Bahasa inggris, dan Bahasa arab. Selain itu membantu anak mengenali bentuk buah, serta tata cara pengucapan nama buah yang benar dalam 3 bahasa tersebut. Game ini dapat digunakan sebagai salah satu media alternatif edukasi/pembelajaran oleh guru Pendidikan Anak Usia Dini (PAUD) dalam mengubah cara belajar konvensional menjadi cara belajar simulasi game, sehingga dapat menarik minat anak dan mengembangkan daya imajinasi, serta melatih pendengaran anak karena game dilengkapi tidak hanya dengan gambar dan tampilan yang menarik juga pelengkap suara pengucapan bahasa yang benar.
IMPLEMENTASI BERMAIN LEGO SEBAGAI PEMBELAJARAN HARIAN UNTUK PENGEMBANGAN KREATIFITAS ANAK USIA DINI
Authors: Imroatun Imroatun , Fadilatunnisa Adella , Hasanah Nur , Rahayu Supriati Hardi 
Published: August 2022

Penelitian ini dilaksanakan untuk mengidentifikasi pelaksanaan bermain lego sebagai pembelajaran harian dalam mengembangkan kreativitas anak usia dini berusia 5-6 tahun di KB-TKIT Iqra School (TKITIS) Kota Serang Banten. Penelitian proses kreatifitas pada siswa kelas B ini menggunakan metode kualitatif dengan eksplorasi data melalui guru kelas sebagai informan serta pengamatan partisipatif dari peneliti selain dokumentasi. Analisis data terdiri dari beberapa tindakan, yaitu klasifikasi, reduksi, dan penyampaian data, dan generalisasi dalam kesimpulan. Melalui tahapan kreatifitas dari Wallas, penelitian kemudian dijabarkan. Proses awal merupakan persiapan dimana pengggalian pengetahuan sebagai dasar pemecahan masalah. Selanjutnya, masa Inkubasi dimana terjadi pendalaman langkah-langkah pemecahan permasalahan terjadi di dunia pra sadar. Iluminasi menjadi fase berikutnya dimana inspirasi atau gagasan timbul untuk memperbaharui atau menyempurnakan langkah pemecahan. Proses terakhir merupakan verifikasi dalam bentuk aktivitas evaluasi terhadap gagasan kreatif dalam pemecahan masalah pada kondisi nyata. Hasil penelitian menunjukkan bermain lego dapat mengembangkan kemampuan kreativitas siswa bersamaan pengembangan yang lain secara sinergis dimana guru telah memberikan jaminan suasana yang kondusif bagi terciptanya ide-ide kreatif selama bermain Mengingat manfaat pengembangan anak yang besar, pemerintah disarankan terlibat untuk menggalakkan penggunaanya dalam pendidikan anak usia dini.