bluuebunny/crossref_metadata_2025_split huggingface dataset:
Management of Complicated Choledochal Cyst in Children: Ultrasound-Guided Percutaneous External Drainage and Subsequent Definitive Operation
Authors: Yan Jiayu , Lv Chuankai , Zhang Dan , Zheng Mingkang , Peng Chunhui , Pang Wenbo , Chen Wei , Wang Siwei , Wang Xiaoman , Chen Yajun 
Published: November 2022

Abstract
Objective
The purpose of this study was to retrospectively analyze the outcomes of the combination of ultrasound-guided percutaneous external drainage (US-PED) and subsequent definitive operation to manage complicated choledochal cyst in children.
Methods
This study included 6 children with choledochal cyst who underwent initial US-PED and subsequent cyst excision with Roux-en-Y hepaticojejunostomy between January 2021 and September 2022. Patient characteristics, laboratory findings, imaging data, treatment details, and postoperative outcomes were evaluated.
Results
Mean age at presentation was 2.7 ± 2.2 (0.5–6.2) years, and 2 patients (2/6) were boys. Four patients (4/6) had a giant choledochal cyst with the widest diameter of ≥ 10 cm and underwent ultrasound-guided percutaneous biliary drainage on admission or after conservative treatments. The other 2 patients (2/6) underwent ultrasound-guided percutaneous transhepatic cholangial drainage and percutaneous transhepatic gallbladder drainage due to coagulopathy, respectively. Five patients (5/6) recovered well after US-PED and underwent the definitive operation, whereas 1 patient (1/6) had liver fibrosis confirmed by Fibroscan and ultimately underwent liver transplantation 2 months after US-PED. The mean time from US-PED to the definitive operation was 12 ± 9 (3–21) days. The average length of hospital stay was 24 ± 9 (16–31) days. No related complications of US-PED occurred during hospitalization. At 10.2 ± 6.8 (1.0–18.0) months follow-up, all patients had a normal liver function and US examination.
Conclusions
US-PED is technically feasible for choledochal cyst with giant cysts or coagulopathy in children, which can provide suitable conditions for subsequent definitive operation with a good overall prognosis.
Trial registration:
Retrospectively registered
In-situ-precipitation three-dimensional printing and photocatalytic applications of highly ordered interconnected submicron-scale pores in silver atomic cluster–silver chloride photocatalyst structures
Authors: Chen Guan-Chen , Huang Wei-Tse , Lee Po-Ching , Lin Ching-Bin 
Published: November 2022

Abstract
In this study, a silver atomic cluster(Ag@)/silver chloride photocatalyst structure with high porosity and a highly ordered interconnected three-dimensional (3D) porous network was prepared through a novel in-situ-precipitation 3D printing technique. Photocatalytic dye degradation and the sterilization of Escherichia coli under irradiation with visible light and ultraviolet light revealed that the photocatalyst structure had a strong degradation effect on the aqueous solutions of Orange II azo dye and methylene blue dye (both containing hydrogen peroxide) and that the kinetic properties were consistent with those of a pseudo-first-order kinetics. E. coli was sterilized within a short period, and the kinetics followed those of pseudo-first-order and hyperbolic kinetics. After five repetitions of dye degradation, the degradation rates of the Orange II azo and methylene blue dyes were maintained at approximately 89.8% and 88.2%, respectively, which indicated that the prepared photocatalyst structure had high durability and reliability.
Are silver nanoparticles the “silver bullet” to promote diterpene production in Stevia rebaudiana?
Authors: Andújar Ivan , González Marielys , García-Ramos Juan Carlos , Hajari Elliosha , Bogdanchikova Nina , Pestryakov Alexey , Concepción Oscar , Lorenzo José Carlos , Morgado Maritza Escalona 
Published: November 2022

Abstract
S. rebaudiana is a sought after sweetener because of its low-calorie properties. However, the supply of suitable quantities of high quality propagation material is limited by inefficient propagation methods using conventional strategies. In vitro techniques combined with nanotechnology tools offer an attractive alternative not only for improved propagation but also for the stimulation of secondary metabolites which represent the targeted sweetener product for this crop. This short report provides an evaluation of silver nanoparticles applied in temporary immersion bioreactors for the abovementioned purpose. Different levels of AgNPs were supplied (0.0–37.5 mg/L) and after 21 d of growth, morphological and biochemical indicators were evaluated. Silver nanoparticles at 25 and 37.5 mg/L decreased shoot multiplication rate, shoot length, and the number of nodes and leaves per shoot compared with the control while no adverse effect was found at the lower tested concentration (12.5 mg/L). Shoot fresh and dry weights also showed statistically significant differences. Regarding the biochemical phenotypes, chlorophyll a, carotenoids and soluble phenolics were increased in plants supplied with 25 mg/L AgNPs, with the latter two indicators suggesting oxidative stress. Interestingly, endogenous levels of diterpenes were significantly increased with the application of 12.5 mg/L AgNPs. It is suggested that AgNPs show potential to act as elicitors to promote the production of diterpenes in stevia but that further work is required to understand the balance between oxidative damage and secondary metabolite production and that optimization of the protocol is required to improve the propagation potential of this strategy.
Use of Tomato, Carrot, and Beetroot Powder as Fish Feed Additive and Their Effects on Growth, Carotenoid Deposition, Muscle Composition, and Palatability of Barbonymus Gonionotus (Silver Barb)
Authors: Hosen Md. Rony , Islam Md. Shahidul , Jaman Atik Uj , Hasan Shihab , Rahman Md. Mahabubur 
Published: November 2022

Abstract

The present study was conducted to investigate the effects of three plant-based dietary pigment sources on the growth, carotene deposition, muscle quality, and palatability of Barbonymus gonionotus. A 90-day feeding trial was conducted in twelve cages under four treatments and three replicates. A commercial feed was used as control (CF), where three other feeds were formulated by adding 2% tomato (TM), carrot (CR), and beetroot (BR) powder to the commercial feed. Fifteen B. gonionotus juveniles with average weight ranging from 75.31 ± 6.43g to 76.44 ± 6.51g were stocked in each cage and the experimental feeds were supplied at 5% of their body mass. Fish were sampled fortnightly and growth and feed utilization indices were estimated at the end of the trial. The highest mean weight gain (193.89 ± 12.31g) and specific growth rate (1.41 ± 0.08%) were found in CR while the lowest in CF (124.35 ± 9.20g and 1.07 ± 0.07%). No significant difference was found in the survival rate among the treatments. CR also showed the best feed conversion (1.59 ± 0.16), and protein efficiency ratio (3.07 ± 0.31) followed by TM, BR, and finally CF. Significantly higher carotenoid content was recorded in CR (4.31 ± 0.30mg/g) while the lowest was found in CF(0.29 ± 0.19mg/g). Results of proximate composition analysis of fish muscle showed no significant difference across the treatments. For the palatability test, a significantly higher organoleptic score was recorded in CR (25.54 ± 0.57) while the lowest was found in CF (19.52 ± 0.77). The study concludes that 2% carrot powder supplementation in feed is more suitable for enhancing the growth, flesh color, and palatability of B. gonionotus.
Trial Registration No.: RU-MSR1611067151
Diabetes-mediated elevated ferroptosis of endothelial cells accelerates blood- spinal cord barrier disruption in spinal cord injury rat
Authors: Wu Man , Zhang Susu , Zhao Jiaxin , Wu Xuejuan , Zhou Yongxiu , Du Anyu , Wang Beini , Cai Shufang , Zhou Mei , Xie Ling , Jiang Chang , Xiao Jian , Wu Yanqing 
Published: November 2022

Abstract
Diabetes significantly aggravates spinal cord injury (SCI). The pathological mechanisms underlying it were still unclear, particularly the role of diabetes on blood spinal cord barrier (BSCB) after SCI. Endothelial cells (ECs) are the important component of BSCB. Here, we built the type 1 diabetes (T1D) combined with SCI rat model and tried to elucidate the role of diabetes on ECs after SCI. We confirmed that SCI impairs the permeability of BSCB and then blocks the recovery of locomotor function of rat, more importantly, diabetes significantly exacerbates it. Diabetes obviously induced the elevated ferroptosis level of ECs in spinal cord after SCI. Ferrostatin-1(Fer-1, ferroptosis inhibitor) administration significantly suppressed the ferroptosis level of ECs, and subsequently reversed the adverse role of diabetes on BSCB permeability and locomotor function of SCI rat. Mechanistic studies further observed that diabetes significantly activates RAGE signaling in ECs and induces excessive oxidative stress with abundance of ROS and abnormal mitochondria function in vivo and in vitro. After SCI, Fer-1 treatment also ameliorated diabetes-induced excessive oxidative stress level of ECs in spinal cord. Additionally, the human umbilical vein endothelial cells (HUVECs) were co-treated with high glucose, high lipid and H2O2 to mimic diabetes combined with SCI condition. The role of hyperglycemia on ferroptosis of ECs were also verified in vitro. In summary, diabetes significantly triggered the ferroptosis level of ECs via inducing elevated oxidative stress, and thus aggravated BSCB destruction of SCI rat, suggesting that ferroptosis will be a key target for the treatment of diabetes combined with SCI.
Contrasting prediction skill and predictability of precipitation between Meiyu and rainy season in North China in ECMWF
Authors: Wu Qiong , Zheng Zhihai , Li Lei , Wu Shanshan , Liu Yanan 
Published: November 2022

Abstract
The rainy season in the Yangtze River valley (called Meiyu ) and North China are the main stages with the northward advance of the East Asian summer monsoon. This study investigates the precipitation prediction skills between Meiyu and rainy season in North China using the S2S hindcast data from the European Centre for Medium-Range Weather Forecast (ECMWF) during 2001–2019. The precipitation forecast skill in the Meiyu rainy season is higher than in the rainy season in North China. Moreover, the forecast skill in south of the Yangtze River is better during the Meiyu rainy season, while most areas show negative performance in the rainy season in North China. In the Meiyu rainy season, the single-blocking covering from east of the Lake Baikal to the Sea of Okhotsk in the Asian high latitude and the altitude anomaly over the low latitude ocean area have a significant influence on the precipitation, however, the model’s response to these two key areas is different. For the rainy season in North China, the 500 hPa height anomaly over northeast China has a significant impact on the precipitation in the observation, but this influence relationship disappeared in the model. The model biases are both in the circulation and its influence on precipitation. The precipitation forecast skill and their biases in the two rainy seasons are different. Specifically, during the Meiyu rainy season, the prediction skills of circulation in low latitudes are high, and the relationship between circulation and precipitation is also well captured. However, the prediction of circulation in high latitude circulation have less skillful. During the rainy season in North China, the prediction skills of the circulation in the key areas are relatively high, but the relationship between circulation in key areas and precipitation are not captured, or even the opposite. At the same time, it is noted that there are biases in the response of some circulations to the El Nino state in the previous spring at high latitudes in the model. To sum up, the decline in prediction skills with the northward advance of the East Asian summer monsoon indicated that the predictability in high latitudes play a key role.
The effect of a formulated feed on the body growth and gonads quality of purple sea urchin (Paracentrotus lividus) aquaculture produced
Authors: Araújo João , Loureiro Paulo , Candeias-Mendes Ana , Gamboa Ana , Bandarra Narcisa , Cardoso Carlos , Soares Florbela , Dias Jorge , Pousão-Ferreira Pedro 
Published: November 2022

Abstract
Sea urchin gonads are a prized gorumet product in many areas of the globe, and wild populations are threatened by increasing demand, making this species a very desirable product in aquaculture. Due to the unique needs of each stage of the life cycle, a viable food protocol that seeks to satisfy each stage while optimizing production profitability is required. The objective of this work was to test a formulated feed for sea urchins, through the analysis of somatic growth, gonad development and their fatty acid profile. These results were compared with sea urchins fed natural food (Ulva spp.) At the end of the trial Paracentrotus lividus juveniles fed inert diet had higher total wet weight gain, total specific growth rate, and gonadosomatic index than those fed with macroalgae. In comparison to sea urchins fed fresh Ulva spp., inert diet showed lower feed conversion ratios and higher protein efficiency ratios. Fatty acid contents of the gonads of each treatment were found to be similar. The DHA levels in the gonads of sea-urchins fed the formulated feed, were significantly higher. It was possible to record the biosynthesis activity of some fatty acids such as 20:4 ω6, 16:4 ω3, and 20:3 ω3. It was found that the presence of some essential fatty acids, such as DHA and EPA, in the gonads is only dependent on the food profile. The addition of a DHA-rich ingredient in the formulated feed may have been preponderant in the constitution and development of the sea-urchins’ gonads.
Mechanical Power Increases in the Preterm Lung During the Respiratory Transition at Birth
Authors: Tingay David Gerald , Naidu Hannah , Tingay Hamish Duguid , Pereira-Fantini Prue M. , Kneyber Martin C.J. , Becher Tobias 
Published: November 2022

Abstract
Background
High mechanical power is a major contributor to lung injury and mortality in adults receiving mechanical ventilation. To date the role of mechanical power in neonatal lung injury is unknown. The aim of this study was to define the components of mechanical power in an established lamb model of preterm respiratory disease undergoing a standardised mechanical ventilationstrategy from birth during three distinctly different, but important, respiratory states with unique changes in lung mechanics.
Methods
19 preterm lambs supported with mechanical ventilation from birth to 90 min. During this period each lamb was exposed to 1) the respiratory transition to air-breathing from an entirely fluid-filled lung (rapid aeration and fall in resistance), 2) commencement of tidal ventilation (5.5-8.0 ml/kg) in an acutely surfactant-deficient state (low compliance) and 3) exogenous surfactant therapy (improved aeration and compliance). Total, tidal, resistive and elastic-dynamic mechanical power were calculated from the flow, pressure and volume signals for each inflation.
Results
All components of mechanical power increased during lung aeration from birth to 5 minutes, before again falling immediately after surfactant therapy. Before surfactant therapy tidal power contributed 70% of total mechanical power, and 53.7% after. The contribution of resistive power was greatest at birth, demonstrating the initial high respiratory system resistance at birth.
Conclusions
Mechanical power was able to define the mechanical events associated with preterm lung injury. This suggests that mechanical power may have an important, and unrecognised, role in neonatal lung injury and protection.
Eco-friendly and Recyclable Evaporator Based on Discarded Cigarette Filters for High-efficiency and Stable Solar Desalination
Authors: Gong Haoran , Chen Ze , Ge Can , Liu Yingcun , Li Wan , Le Pengtao , Xu Weilin , Xu Duo , Liu Keshuai 
Published: November 2022

Abstract

Solar steam generation is a promising technology to realize efficient and green desalination with a minimized carbon footprint. Discarded cigarette filters (CFs) cause significant harm to the environment but have good recycling potential for solar steam generation. In this study, an efficient thermally-positioned material (AC-CF), which uses renewable cellulose acetate CFs and an acetylene carbon black (AC) coating as an absorber, was developed for application as a solar steam generator. The AC-CF exhibited superhydrophilic characteristics and extensive solar absorption (approximately 100%). These properties enable the resulting AC-CF to exhibit rapid water transport and a strong photothermal conversion ability, with an outstanding evaporation rate of 1.81 kg·m-2·h-1 under 1 sun illumination. The evaporator can remove most impurities and dye molecules during outdoor operation. Subsequently, the AC-CF evaporator was dissolved and recycled using N, N-dimethylformamide, and the recycling method yielded good results. This method for preparing absorbers reduces manufacturing costs and guides the potential practical application of recycled polymer resources using discarded CFs.
Messaging Strategies of Ukraine and Russia on Telegram during the 2022 Russian Invasion of Ukraine
Authors: Ghasiya Piyush , Sasahara Kazutoshi 
Published: November 2022

Abstract

The popularity of the instant messaging app Telegram in Ukraine and Russia
was strong even before the still-ongoing Russian invasion of Ukraine. However, since
24 February 2022 (when the Russian invasion began), it has seen huge increases in
subscribers and even become the primary communication and news source in Ukraine.
In this exploratory research, we analysed Telegram channels from both Ukraine
(@UkraineNow — the official channel of the Ukrainian government, and @V_Zelenskiy_
official — the official channel of Ukraine’s President Volodymyr Zelenskyy) and
Russia (@rt_russian — the official channel of the news network RT) to discern the
content of posts during this invasion. Our analysis of 37,172 posts in total showed
that while @UkraineNow is particularly being used to communicate invasion-related
news, @rt_russian is working as merely an extension of RT, which is part of the
pro-Kremlin propaganda and disinformation ecosystem. However, Zelenskyy has opted
for a completely different approach: he has used his Telegram channel to encourage
Ukrainians and garner support from the World. The present conflict is at a critical
juncture, and our timely research seeks to determine how both countries’ governments
are utilizing Telegram as a weapon for the information war and what impact this has
on ground.
Ellagic acid increases implantation rates with its antifibrotic effect in the rat model of intrauterine adhesion
Authors: Saribas Gulistan Sanem , Dizakar Ozen Akarca , Ozogul Candan , Celik Ekin , Ergoren Mahmut Cerkez 
Published: November 2022

Abstract
Background: Intrauterine adhesions (IUA) are defined as the adhesion of opposing endometrial tissue with dense fibrous adhesive bands within the uterine cavity. With the increase in cesarean sections and endometrial surgical procedures, intrauterine adhesions have become a problem with increasing incidence and decreasing implantation. The purpose of the study was to investigate the effect of ellagic acid (EA), a phenolic compound, on fibrosis in IUA model rats. Another goal of the study was to increase endometrial receptivity with EA.
Methods and Results: The groups in the study were planned as control, DMSO, EA, IUA, IUA+DMSO, and IUA+EA, with 8 Sprague Dawley rats in each group. At the end of the experiment, the uterine tissues of the rats were removed. Histochemical staining was used to validate the IUA model and determine the degree of fibrosis. The levels of some fibrosis-related genes and proteins in the obtained uterine tissues were evaluated. In addition, implantation rates were determined. In our findings, it was observed that the fibrotic structure was decreased in the treated IUA+EA group compared to the IUA group, while fibrotic improvement was supported by down-regulation of TGFβ1 activity and up-regulation of BMP7 activity. The increase in the expression of the endometrial marker LIF with EA treatment was consistent with the increase in implantation rates with treatment.
Conclusions: As a result of the study, it can be said that EA applied as a treatment against IUA causes healing in uterine tissue by reducing fibrosis and increases implantation rates by increasing endometrial receptivity.
The “A” in the acronym: Visibilities of asexuality in news media
Authors: Webster Kyle 
Published: November 2022

Abstract
The absence of asexuality in media and popular culture suggests that it suffers from symbolic annihilation. Against this cultural absence of asexuality, advocacy groups have worked to increase the visibility and education of asexuality in media, and news and entertainment media have included asexuality in recent years. However, as elaborated by Tuchman (1978), the symbolic annihilation model suggests that when social groups are not omitted from representation, they are trivialized and condemned. To examine whether this symbolic annihilation model applies to media representations of asexuality, this study examined the context, frequency, and tones of references to asexuality in news stories published in 2020. The findings show that when it is referenced, it is largely minimized. However, in news media that references asexuality frequently instead of minimally, asexuality is depicted positively, indicating that trivialization and condemnation are not as present as the symbolic annihilation model would suggest.
Prevalence and associated risk factors for Salmonella enterica contamination of cow milk and cottage cheese Ethiopia
Authors: Bedassa Abdi , Nahusenay Henok , Asefa Zerihun , Sisay Tesfaye , Girmay Gebrerufael , Kovac Jasna , Vipham Jessie L. , Zewdu Ashagrie 
Published: November 2022

Abstract
Animal sourced foods, such as dairy products, are common sources of Salmonella enterica, a foodborne pathogen of increasing global concern, particularly in developing countries. In Ethiopia, most data on the prevalence of Salmonella in dairy products is highly varied and limited to a specific region or district. Furthermore, there is no data available on the risk factors for Salmonella contamination of cow milk and cottage cheese in Ethiopia. This study was therefore conducted to determine the presence of Salmonella throughout the Ethiopian dairy value chain and to identify risk factors for contamination with Salmonella. The study was carried out in three regions of Ethiopia, including Oromia, Southern Nations, Nationalities and Peoples, and Amhara during a dry season. A total 912 samples were collected from milk producers, collectors, processors, and retailers. Samples were tested for Salmonella using the ISO 6579-1: 2008 method, followed by PCR confirmation. Concurrent with sample collection, a survey was administered to study participants to identify risk factors associated with Salmonella contamination. Salmonella contamination was highest in raw milk samples at the production (19.7%) and at milk collection (21.3%) levels. No significant difference in the prevalence of Salmonella contamination among regions was detected (p > 0.05). Regional differences were apparent for cottage cheese, with the highest prevalence being in Oromia (6.3%). Identified risk factors included the temperature of water used for cow udder washing, the practice of mixing milk lots, the type of milk container, use of refrigeration, and milk filtration. These identified factors can be leveraged to develop targeted intervention strategies aimed at reducing the prevalence of Salmonella in milk and cottage cheese in Ethiopia.