bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence and associated risk factors for mental health problems among patients with polycystic ovary syndrome in Bangladesh: A nationwide cross—Sectional study
Authors: Hasan Moynul , Sultana Sumaya , Sohan Md. , Parvin Shahnaj , Rahman Md. Ashrafur , Hossain Md. Jamal , Rahman Mohammad Saydur , Islam Md. Rabiul 
Published: June 2022

Background
Polycystic ovary syndrome (PCOS) is a common female reproductive endocrine problem worldwide. The prevalence of mental disorder is increasing among PCOS patients due to various physical, psychological, and social issues. Here we aimed to evaluate the mental health and associated factors among women suffering from PCOS in Bangladesh.

Methods
We performed an online cross-sectional survey among 409 participants with PCOS using Google Forms. We used structured questionnaires to collect socio-demographic information and lifestyle-related factors. Also, we applied patient health questionnaire (PHQ-9), generalized anxiety disorder (GAD-7) scale, and UCLA loneliness (UCLA-3) scale for psychometric assessment of the participants. Finally, we applied several statistical tools and performed data interpretations to evaluate the prevalence of mental health disorders and associated factors among patients with PCOS in Bangladesh.

Results
Prevalence of loneliness, generalized anxiety disorder and depressive illness among the women with PCOS were 71%, 88%, and 60%, respectively. Among the mental illness, mild, moderate, and severe cases were 39%, 18%, and 14% for loneliness; 39%, 23% and 26% for generalized anxiety disorder; and 35%, 18%, and 7% for depressive disorder. According to the present findings, obesity, financial condition, physical exercise, mealtime, food habit, daily water consumption, birth control method, and long-term oral contraceptive pills contribute to developing mental health disorders among females with PCOS in Bangladesh.

Conclusion
According to present study results, high proportion of women suffering from PCOS experience several mental disorders in Bangladesh. Although several socio-demographic and lifestyle-related factors were found to be associated with the poor mental health of women with PCOS; however, PCOS itself is a condition that favors poor physical and psychological health. Therefore, we recommend proper treatment, public awareness, and a healthy lifestyle to promote the good mental health of women suffering from PCOS.
Provider perspectives on the use of motivational interviewing and problem-solving counseling paired with the point-of-care nucleic acid test for HIV care
Authors: Atkins Dana L. , Violette Lauren , Neimann Lisa , Tanner Mary , Hoover Karen , Rao Deepa , Stekler Joanne D. 
Published: June 2022

Aims
To evaluate provider perspectives on the use of a point-of-care nucleic acid test (POC NAT) and preferential opinions for motivational interviewing (MI) or problem-solving counseling (PSC) as an ultra-brief intervention for patients experiencing challenges to antiretroviral therapy (ART) adherence.

Methods
A qualitative study was conducted among providers at an HIV care clinic in Seattle, Washington. Ten in-depth interviews with HIV care providers were completed, which explored determinants of acceptability, feasibility and preferences for a combined adherence counseling and POC NAT intervention for patients living with HIV. Interviews were analyzed through consensus coding and the Five A’s Framework to inform thematic analysis.

Results
Providers favored the use of a combined adherence counseling technique and POC NAT for their non-adherent patients living with HIV. Providers believed the intervention was an improvement on current assessment and advising practices. However, concerns about extended wait times for the POC NAT results influenced perceptions about feasibility around clinic flow and incorporation into clinic practice. Providers believed that acceptability of POC NAT implementation would be enhanced by including a subset of patient populations whom tend to be in the clinic for longer periods, and in tandem face greater ART adherence challenges.

Conclusion
The GAIN Study will be the first project to evaluate the implementation of POC NAT in the U.S. Continued formative work is ongoing and may illustrate how best to address feasibility and concern around the two-hour time to result. The planned GAIN study will incorporate some of the findings found in this qualitative study and pilot this intervention, including a time-in-motion analyses of clinic flow, which may help reduce perceived wide-scale adaptation of POC NAT and ART adherence counselling among PLHW. Future work, including a shorter time to results and/or lower limit detection could make a significant improvement in the provision of HIV care.
Creating a Global Cultural City via Public Participation in the Arts: Conversations with Hong Kong’s Leading Arts and Cultural Administrators, Patrick Lo, Wei-en Hsu, Stephanie H. S. Wu, J. Travis and Dickson K. W. Chiu (eds) (2021)
Authors: Boulil Djamila 
Published: June 2022

Review of: Creating a Global Cultural City via Public Participation in the Arts: Conversations with Hong Kong’s Leading Arts and Cultural Administrators, Patrick Lo, Wei-en Hsu, Stephanie H. S. Wu, J. Travis and Dickson K. W. Chiu (eds) (2021)
New York: Nova Science Publishers, 369 pp.,
ISBN 978-1-53619-719-8, h/bk, $230.00,
ISBN 978-1-53619-879-9, e-book, $230.00
A study of database performance sensitivity to experiment settings
Authors: Wang Yang , Yu Miao , Hui Yujie , Zhou Fang , Huang Yuyang , Zhu Rui , Ren Xueyuan , Li Tianxi , Lu Xiaoyi 
Published: June 2022

To allow performance comparison across different systems, our community has developed multiple benchmarks, such as TPC-C and YCSB, which are widely used. However, despite such effort, interpreting and comparing performance numbers is still a challenging task, because one can tune benchmark parameters, system features, and hardware settings, which can lead to very different system behaviors. Such tuning creates a long-standing question of whether the conclusion of a work can hold under different settings.
This work tries to shed light on this question by reproducing 11 works evaluated under TPC-C and YCSB, measuring their performance under a wider range of settings, and investigating the reasons for the change of performance numbers. By doing so, this paper tries to motivate the discussion about whether and how we should address this problem. While this paper does not give a complete solution---this is beyond the scope of a single paper, it proposes concrete suggestions we can take to improve the state of the art.
Determination of aluminum concentrations in biological specimens: application in the clinical laboratory
Authors: San Martín Sonia Pérez , Bauçà Josep Miquel , Martinez-Morillo Eduardo 
Published: June 2022

Abstract
Aluminum enters the body primarily through diet or occupational exposure, and is cleared through urine. However, this trace element may accumulate and cause toxicity in subjects with renal insufficiency, and even in dialysis patients. The mechanism of aluminum toxicity is related to increased oxidative and inflammatory stress, iron and calcium dyshomeostasis, or cholinergic dysregulation, among other. A review was conducted on the specimens and analytical methods used to determine aluminum in biological specimens and dialysis water. This paper describes the most relevant aspects related to quality assurance. This is a practical guideline for the development and implementation of a reliable method for determination of aluminum in the clinical laboratory. Serum aluminum is the main biomarker of toxicity. For cases of chronic exposure, urine testing is recommended. At present, inductively coupled plasma mass spectrometry (ICP-MS) is the gold-standard determination method, since it has been proven to have the best quantification limits, selectivity and robustness. Clear recommendations are provided in relation to the specimens used for aluminum determination. Relevant pre-analytical, analytical, and post-analytical considerations are also presented.
Active legumain promotes invasion and migration of neuroblastoma by regulating epithelial-mesenchymal transition
Authors: Zhang Min , Zhu Jianhua , Wang Wei , Jiang Zhiteng 
Published: June 2022

Abstract
Neuroblastoma (NB) is a commonly occurring malignancy in children. Epithelial-mesenchymal transition (EMT) is an adaptive change in promoting tumor metastasis. As an important factor in regulating tumor metastasis, whether legumain could promote metastasis of NB by EMT is still unexplored. Legumain is the active form of prolegumain, abundant in tumor plasma. So in the current study, different forms of legumain were identified in NB. Second, correlation analysis of N-cadherin and active legumain was identified by western blot analysis. Third, legumain gene amplification or gene knockdown were proceeded to examine the effect of legumain on EMT by scratch and transwell assay; meanwhile, active mature legumain or its asparagine endopeptidase (AEP) inhibitor was also added in. Finally, legumain can be detected differently in NB cells. Changes in legumain could influence NB metastasis by regulating EMT markers (e.g., N-cadherin, vimentin, and slug). Besides, the effect of legumain on EMT by its AEP activity was proved by intervention experiment of AEP gene transfection and gene knockdown experiments or adding recombinant human legumain suspension or specific inhibitor of AEP in NB cells (p < 0.05). These results suggest that legumain can promote invasion and migration of NB by regulating EMT, and EMT of NB is regulated by AEP activity of legumain, which can be inhibited by a specific AEP inhibitor.
How Does Institutional Context Influence Entrepreneurship Education Outcomes? Evidence from Two African Countries
Authors: Fahinde Charles , Abodohoui Alexis , Mayuto Radjabu , Su Zhan 
Published: June 2022

Abstract
In this paper, we proposed an analytical framework based on the institutional theory to analyze the effect of institutional context on the impact of entrepreneurship education (EE). The influence of institutional environment was captured through three variables, namely perceived government support, perceived cultural norms, and social legitimacy of entrepreneurship. Based on a sample of 788 respondents from two African countries, our results show that beyond EE, institutional context is equally a determining factor of students’ entrepreneurial intention. Thus, a favorable institutional environment increases the students’ entrepreneurial intention. Our results also reveal that the positive effect of EE is higher when government policies are conducive to entrepreneurship development while it is lower when socio-cultural context (cultural norms, social legitimacy) is conducive to entrepreneurship. Thus, this study shows that informal institutions have a contingency effect while formal institutions play a complementary role in the impact of EE on students’ entrepreneurial intention.
Aspectual marking from a typologically uncommon origin: a quantitative account of the development ofhamē(w)in Middle Persian
Authors: Mofidi Roohollah , Petré Peter 
Published: June 2022

AbstractThis article follows the early grammaticalization path of a durative adverb to an aspect marker for a range of aspectual uses including durative, focalized, and habitual. In a usage-based approach, we investigate the behavior ofhamē(w)in a Middle Persian database with respect to several grammatical variables, and we check its developmental path against the model proposed for the Romance languages by Bertinetto, Ebert and de Groot, aiming to uncover the amount of similarities/differences between those Romance languages and Persian. The results show that the lexical origin of the structure investigated locates Middle Persian in stage (iii) of the model, and the development documented deviates from the rest of the model in various respects. Furthermore, the usual priority of past tense in progressive developments is not observed: the adverb is originally present-oriented, but past tense usage increases as the grammaticalization proceeds.
Circular shape MIMO antenna sensor for breast tumor detection
Authors: Gupta Ankit Kumar , Rao Praveen Kumar , Mishra Rajan 
Published: June 2022

Abstract
In this paper, a compact circular shape ultra-wide microstrip antenna is proposed for the detection of breast tumor. The proposed antenna is a two-port MIMO antenna of 1 × 2 elements. The dimensions of the proposed antenna are 34 mm × 18mm × 1.6 mm. It is designed over a lower-cost FR-4 epoxy substrate with a partial ground plane. The antenna is operated between the frequency range of 3.1–9.6 GHz. Isolation between the antenna element is less than −22 dB from 3.1 GHz to 7 GHz and −25 dB between 7 GHz and 10.6 GHz. The obtained ECC of the designed MIMO antenna is less than 0.01 and also DG is almost 10 dB in the entire UWB range. Further, the 3D breast phantom model is also simulated for analysis of the effect of SAR. Due to the variation in the electrical properties of cancerous cells and healthy cells it is possible to identify the cancerous tumor using SAR analysis. The obtained maximum Average SAR value without a tumor is 41.97 W/kg and with a cancerous tumor is 72 W/kg. Also, the variation in reflection coefficient helps to detect the tumor of the same composition but having different locations and having different sizes inside breast phantom. The principal component analysis is done to change the multi-variation in reflection coefficients data value to a single point value for better analysis.
Information model of low-voltage distribution IoT monitoring terminal based on IEC 61850
Authors: Huang Guozheng , Wang Jinghua , Huang Mengzhe , Wu Hongbo , Zhan Yijia , Cai Ziheng 
Published: June 2022

Abstract
Low-voltage distribution lines lack efficient monitoring. With the massive proliferation of distributed energy resource supply, it is necessary to establish an effective monitoring system for low-voltage distribution lines to ensure the electrical safety and continuity of power supply services. This paper proposes monitoring system for low-voltage distribution lines based on the Internet of things (IoT) technology. An IoT based monitoring system contains a large number of low-voltage monitoring terminals, different manufacturers, and different types of terminal equipment to solve the interconnection problem of information interaction. This paper first analyzes the terminal functional communication requirements based on IEC 61850 standards. Further, the information models required by the electrical volume collection and non-electric quantity collection functions are studied. The information modeling for different types of monitoring terminal equipment is presented and thus provide the configuration suggestions. The monitoring terminal based on the information model developed in this paper is applied in a university campus to realize the monitoring of low-voltage lines and distributed power supply.
Understanding salient trajectories and emerging profiles in the development of Chinese learners’ motivation: a growth mixture modeling approach
Authors: Yu Hanjing , Lowie Wander , Peng Hongying 
Published: June 2022

Abstract
Based on the theoretical framework of the L2 Motivational Self System (L2MSS), the present study aims to make a methodological contribution to L2 motivation research. With the application of a novel growth mixture modeling (GMM) technique, the study depicted developmental trajectories of three motivational variables (ideal L2 self, ought-to L2 self, and L2 learning experience) of 176 Chinese tertiary-level students over a period of two semesters. Results showed two to three salient classes with typical developmental patterns for the three motivational variables respectively, with which the study gained fresh insights into the developmental processes of motivation beyond the individual level. Our study further established three main multivariate profiles of motivation characterized by a distinct combination of different motivational variables. The findings extend our understanding of motivational dynamics, providing a nuanced picture of emergent motivational trajectories systemically. Additionally, GMM has shown to be an effective and applicable method for the identification of salient patterns in motivation development, which leads to practical implications.
Reduction as an improvement of a precise satellite positioning based on an ambiguity function
Authors: Cellmer Sławomir , Nowel Krzysztof , Fischer Artur 
Published: June 2022

Abstract
It is well-known that the solution domain has a discrete character in precise satellite positioning because of the integer nature of ambiguities. Therefore, in addition to the classic least squares estimation, the search procedure has to be employed in the computation process to obtain the so-called ‘fixed solution.’ The article’s subject is to improve the search procedure conducted in the coordinate domain. The reduction process is to transform the original math model into an equivalent one in the sense of obtaining the same solution. The reduction aims to increase the efficiency of searching for some parameters, i. e., integer ambiguities. The article presents the concept of employing the reduction procedure to the computation process of precise positioning based on the ambiguity function. The transformation matrix for the reduction is based on the well-known integer decorrelation procedure. Numerical experiment results display a positive impact of the reduction process on the search procedure efficiency. This positive impact is manifested by a dramatic decrease in the number of candidates needed to test all admissible solutions inside the search region. The percentage decrease in that magnitude is at least 50 % for all session lengths and achieves a maximum value of over 75 % for the 10-minute session. Computational time decreases by over 40 % while short sessions are processed. There is no improvement for sessions longer than 15 minutes, but, as explained in the paper, there is no need to improve that magnitude in such cases.
A spherical fuzzy AHP model for contractor assessment during project life cycle
Authors: Abdulkareem Hayder Ghazi , Erzaij Kadhim Raheim 
Published: June 2022

Abstract
Measurement of construction performance is essential to a clear image of the present situation. This monitoring by the management team is necessary to identify locations where performance is exceptionally excellent or poor and to identify the primary reasons so that the lessons gained may be exported to the firm and its progress strengthened. This research attempts to construct an integrated mathematical model utilizing one of the recent methodologies for dealing with the fuzzy representation of experts’ knowledge and judgment considering hesitancy called spherical fuzzy analytic hierarchy process (SFAHP) method to assess the contractor’s performance per the project performance parameters (cost, schedule, quality, leadership, and change management). At the same time, most project control systems are currently applied through software like Primavera P6 or MS Project. These look at a project’s cost and schedule status by following the earned value analysis for finding the performance. Based on decision makers’ preferences, the analytic hierarchy process (AHP) may be used to arrive at the optimum conclusion. AHP approaches are discussed, including AHP, grey-AHP, fuzzy-AHP, and SFAHP weights comparison. Calculation results showed that the spherical fuzzy approach differs significantly from the other approaches where it considers the decision maker’s hesitation when making linguistic multicriteria decisions and then, as a result, recommends applying periodically for performance measurement. This model can be viewed as a valuable way to help the decision-making stakeholders in the construction sector do the best job about critical issues at a suitable time.
Cardiac ion channels associated with unexplained stillbirth – an immunohistochemical study
Authors: Branco Susana Quesado , Batra Gauri , Petts Gemma , Hancock Ainslie , Kerby Alan , Brady Chloe Anne , Heazell Alexander E.P. 
Published: June 2022

Abstract

Objectives
Despite the use of post-mortem investigations, approximately 20% of stillbirths remain unexplained. Cardiac ion channelopathies have been identified as a cause of death in Sudden Infant Death Syndrome (SIDS) and could be associated with unexplained stillbirths. This study aimed to understand if the expression or localisation of cardiac ion channels associated with channelopathies were altered in cases of unexplained stillbirths.

Methods
A case control study was conducted using formalin-fixed cardiac tissue from 20 cases of unexplained stillbirth and a control group of 20 cases of stillbirths from intrapartum hypoxia. 4 µm tissue sections were stained using haematoxylin and eosin, Masson’s trichrome (MT) and Elastic van Gieson (EVG). Immunohistochemistry (IHC) was performed using antibodies against CACNA1G, KCNJ2, KCNQ1, KCNH2 and KCNE1. The cardiac conduction system in samples stained with MT and EVG could not be identified. Therefore, the levels of immunoperoxidase staining were quantified using QuPath software.

Results
The nuclear-cytoplasmic ratio of sections stained with haematoxylin and eosin was higher for the hypoxia group (hypoxia median 0.13 vs. 0.04 unexplained, p < 0.001). CACNA1G (unexplained median 0.26 vs. hypoxia 0.30, p=0.009) and KCNJ2 (unexplained median 0.35 vs. hypoxia 0.41, p=0.001) had lower staining intensity in the unexplained stillbirth group. There were no statistically significant differences in the staining intensity of KCNQ1, KCNH2 and KCNE1.

Conclusions
Two ion channels associated with channelopathies demonstrated lower levels of expression in cases of unexplained stillbirth. Further genetic studies using human tissue should be performed to understand the association between channelopathies and otherwise unexplained stillbirths.
Radiochemical separation of 26Al and 41Ca from proton-irradiated vanadium targets for cross-section determination by means of AMS
Authors: Veicht Mario , Mihalcea Ionut , Gautschi Philip , Vockenhuber Christof , Maxeiner Sascha , David Jean-Christophe , Chen Shaohuang , Schumann Dorothea 
Published: June 2022

Abstract
This work exhibits the very first experimentally determined cross sections for 26Al and 41Ca as proton-induced spallation products of metallic vanadium targets. Additionally, the authors describe a radiochemical separation of 26Al and 41Ca from the vanadium matrix and present the theoretically calculated cross-section values as a reference for the experimental ones.