bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Presence of Trihalomethanes and Haloacetic Acids in Tropical Peat Water
Authors: Zevi Yuniati , Qadafi Muammar , Notodarmojo Suprihanto 
Published: June 2022

The presence of dissolved organic matter (DOM) in tropical peat water affects the appearance of trihalomethanes (THMs) and haloacetic acids (HAAs) in natural water sources. However, information about the presence of THM and HAA in tropical peat water is still limited. This study was conducted to determine the presence of THMs and HAAs in tropical peat water taken from a canal and a river in Riau Peatland, Indonesia, influenced by the seasons and the tides. DOM was measured by dissolved organic carbon (DOC) and UV254 absorbance. The presence of THMs and HAAs was determined based on total THM4 and HAA5 and correlated with chloride and bromide concentrations. The concentrations of chloride and bromide in the river water were higher than in the canal water because of tidal influence. Total THM4 in canal water reached 22.70 ± 0.90 and 10.78 ± 0.71 µg/L in the dry and rainy seasons, respectively, but only reached 16.64 ± 1.93 and 5.52 ± 0.05 µg/L in the river water. In contrast to THM4, total HAA5 in the river water was higher than in the canal water and reached 104.01 ± 4.67 and 106.39 ± 9.53 µg/L in the dry and rainy seasons, respectively, but only reached 9.83 ± 0.48 and 56.87 ± 6.11 µg/L in the river water. THM4 predominated in the dry season while HAA5 predominated in the rainy season.
HIỆU QUẢ BỔ SUNG PHỐI HỢP SẮT VÀ KẼM ĐẾN TÌNH TRẠNG THIẾU MÁU, THIẾU SẮT, THIẾU KẼM TRÊN TRẺ 1-3 TUỔI SUY DINH DƯỠNG THẤP CÒI
Authors: Phan Tiến Hoàng , Nguyễn Quang Dũng , Trần Thúy Nga , Nguyễn Thị Lan Phương , Lê Danh Tuyên 
Published: June 2022

Mục tiêu: Đánh giá hiệu quả của việc bổ sung phối hợp sắt và kẽm lên tình trạng thiếu máu, thiếu sắt, thiếu kẽm trên trẻ suy dinh dưỡng (SDD) thấp còi 1- 3 tuổi. Phương pháp: Nghiên cứu can thiệp cộng đồng có đối chứng. Đối tượng: trẻ suy dinh dưỡng (SDD) thấp còi 1- 3 tuổi ở Nhóm can thiệp bổ sung sắt và kẽm và nhóm chứng không bổ sung sắt, kẽm. Kết quả: Sau 6 tháng can thiệp ở nhóm chứng và nhóm can thiệp Hb (g/L) tăng 3,2 ± 12,7 và 2,5 ± 14,9; Ferritin (μg/L) tăng 16,1 ± 31,3 và 24,6 ± 37,9; kẽm huyết thanh (μmol/L) tăng 0,32 ± 2,52 và 1,31 ± 3,30. Thay đổi tỷ lệ thiếu máu, thiếu sắt, thiếu kẽm sau 6 tháng can thiệp ở nhóm chứng và nhóm can thiệp tương ứng như sau: thiếu máu tăng 3% và giảm 6,2%; thiếu sắt giảm 12,1% và 19,6%; thiếu kẽm giảm 1 % và 21,7%. Kết luận: Sử dụng sản phẩm Suppy bổ sung sắt kẽm trong 6 tháng trên trẻ SDD thấp còi 1-3 tuổi có hiệu quả tăng nồng độ Ferritin, kẽm huyết thanh và giảm tỷ lệ thiếu máu, thiếu sắt, thiếu kẽm hơn so với sử dụng sản phẩm Suppy không bổ sung vi chất dinh dưỡng sắt và kẽm.
THỪA CÂN - BÉO PHÌ VÀ CẤU TRÚC CƠ THỂ CỦA NỮ VIÊN CHỨC TRƯỜNG ĐẠI HỌC Y KHOA PHẠM NGỌC THẠCH ĐÁNH GIÁ BẰNG PHƯƠNG PHÁP PHÂN TÍCH KHÁNG TRỞ ĐIỆN SINH HỌC NĂM 2020
Authors: Dương Đông Nhật , Trần Mỹ Nhung , Trương Xuân Bích , Đoàn ThịKim Thoa , Trần Quốc Cường 
Published: June 2022

Nhằm khảo sát thực trạng thừa cân - béo phì của nữ viên chức tại Trường Đại học Y Khoa Phạm Ngọc Thạch, 220 nữ viên chức của trường có độ tuổi từ 20 đến 59 tuổi đã được đo các chỉ số nhân trắc và đánh giá thành phần cơ thể bằng máy phân tích kháng trở điện sinh học Tanita SC - 331S. Kết quả: Tỷ lệ thừa cân – béo phì (BMI ≥ 23) và béo phì (BMI ≥ 25) lần lượt là 27,3% và 13,6%. Tỷ lệ béo phì theo phần trăm mỡ cơ thể (>35%) là 14,1%. Phần trăm mỡ cơ thể trung bình, khối mỡ, mỡ nội tạng và tuổi chuyển hóa tăng dần theo nhóm tuổi với sự khác biệt có ý nghĩa thống kê. Kết luận: Tỷ lệ thừa cân - béo phì của nữ viên chức tại Trường Đại học Y Khoa Phạm Ngọc Thạch là tương đối cao. Tỷ lệ béo phì khi phân loại theo giá trị BMI và khi phân loại theo phần trăm mỡ cơ thể là gần bằng nhau (13,6% và 14,1%) ở điểm cắt BMI 25 kg/m2 và tỷ lệ mỡ 35%.
Đặc điểm khẩu phần của người bệnh phong tàn tật được nuôi dưỡng tại Bệnh viện Da liễu Thái Bình năm 2020
Authors: Phạm Văn Hùng , Trương Hồng Sơn , Ninh Thị Nhung , Phạm Thị Kiều Chinh 
Published: June 2022

Nghiên cứu dịch tễ học cắt ngang được thực hiện tại Bệnh viện Da liễu Thái Bình năm 2020 để đánh giá khẩu phần của bệnh nhân phong bằng phương pháp hỏi ghi 24 giờ.
Khẩu phần của 112 bệnh nhân được đưa vào phân tích mức độ tiêu thụ các chất dinh dưỡng, vitamin và khoáng chất và tính cân đối của khẩu phần. Kết quả cho thấy khẩu phần của người bệnh mới đáp ứng được khoảng 77,7% nhu cầu năng lượng, 78,6% nhu cầu protein; 88,4% nhu cầu lipid và 87,5% nhu cầu glucid theo nhu cầu dinh dưỡng khuyến nghị cho người Việt Nam. Đồng thời tỷ lệ đạt về một số chất khoáng và vitamin trong khẩu phần của người bệnh phong rất thấp, đặc biệt là canxi rất thấp, tỷ lệ canxi và phospho không phù hợp chỉ đạt 0,43, thấp hơn rất nhiều so với khuyến nghị. Cần phân chia đối tượng người bệnh phong theo tình trạng dinh dưỡng (TTDD) để xây dựng thực đơn phù hợp từng nhóm đối tượng có hiệu quả hơn và từng bước cải thiện số lượng, chất lượng bữa ăn.
On the Nonlinear Response of a Tri-SWACH Vessel in Incident Waves
Authors: Onas Adrian S. , Falls Jaye 
Published: June 2022

Abstract
In this article, the nonlinear motion response of a Trimaran with SWATH-type center hull vessel (TriSWACH) is investigated and compared with the linear response using a hybrid method combining a regression analysis of the viscous damping generated by the hulls with a nonlinear potential flow simulation of rigid body motions. The TriSWACH is a hybrid trimaran hull form, developed using the SWATH (small waterplane area twin hull) technology, from which a single small waterplane area center hull is retained. It is designed to keep the magnitude of its motion response below its equivalent monohull counterpart while also benefiting from large intact transverse stability provided by its side hulls. Since a significant portion of the total damping generated by the submerged hull girder is viscous in nature, an accurate prediction of the steady-state motion response near natural frequency is highly dependent upon the correct modeling of the boundary layer flow. The total damping coefficients obtained experimentally from motion response transfer functions are used to augment the potential flow solution and improve the numerical prediction method at large angles of inclination, characteristic of operation in rough weather near the peak frequency of the motion response.

Introduction
SWATH1-type vessels exhibit ship motions less pronounced than a monohull of the same displacement. It has been reported that SWATHs have the potential to significantly reduce the impact of harsh environmental conditions on ship operability (Kennell et al. 1985). Although the interest in SWATH technology in ship design continued over the past few decades, it was recognized that this hull form required modifications in order to accommodate high-speed applications. An example of a TriSWACH concept is shown in Fig. 1, with the main distinguishing features compared to the SWATH-type vessel being the presence of the side hulls and one single main hull.
Staging Aural Fugitivity through Nineteenth-Century Freak Show Archives
Authors: Bainbridge Danielle 
Published: June 2022

This essay analyzes aural fugitivity in archives of nineteenth-century freak show performers Millie Christine McKoy and traces the difficulties in staging these archives for twenty-first-century audiences. Aural fugitivity couples theories of Black fugitivity with sound studies analysis of enslavement and nineteenth-century performance in order to explore the legacies of freak show and sideshow performers who were also enslaved. This essay, taking as an object of analysis the author's own creative work based on these archives, traces the biography of the McKoys alongside their performance strategies that resisted full archival capture through fugitive sound.
A Meta-analysis of the Effect of Selective Serotonin Reuptake Inhibitors on Pain in Fibromyalgia
Authors: Albunayyan Ruoa Faisal 
Published: June 2022

Background: Fibromyalgia is a clinical condition that causes wide spread severe pain, sleep problems, fatigue, and often emotional and mental distress. Patients with fibromyalgia may be more sensitive to pain than others.
Aim: This study aims to screen and evaluate the efficacy and safety of selective serotonin reuptake inhibitors (SSRIs) in the management of pain in patients with fibromyalgia.
Methods: This systematic review and meta-analysis gathered all studies related to selective serotonin inhibitors in the treatment of pain in fibromyalgia, using the databases of PubMed, the Cochrane Library, and Google Scholar. All articles using a visual analog scale (VAS) were included in the review. All duplicates and non-eligible or unavailable full-text studies were excluded. The primary outcome was defined as pain reduction by VAS score. Secondary outcomes were the assessment of the occurrence of adverse effects at any time in the study or premature withdrawal.
Results: The five studies included in the meta-analysis for pain management have moderate heterogeneity. This is shown by the test of heterogeneity with a p-value greater than 0.05 and I2 value less than 50%. If the I2 value is more than 50% and the p-value is significant, this results in differing study results. The result of this meta-analysis shows that the SSRI group had a statistically significant reduction in pain (Z = 2.37, p = 0.02).
Conclusion: Based on the results of the meta-analysis, SSRIs may be considered for pain management for a short-term duration, preferably in female patients aged over 45 years old, in the absence of other health problems except for fibromyalgia. However, close monitoring of the potential withdrawal effects is necessary.
ANTIFEMINISMO, CONSERVADORISMO E PARTICIPAÇÃO POLÍTICA DA MULHER NO BRASIL
Authors: Oliveira Pinto Brena 
Published: June 2022

O presente artigo tem como objetivo debater a participação das mulheres na política no Brasil, a partir das suas experiências eleitorais e considerando as diversas vivências das mulheres na dinâmica política. Dois fenômenos estão no centro dessa análise: o antifeminismo e o conservadorismo. Para isso, se considera o desenvolvimento do feminismo e do movimento de mulheres no Brasil e a participação política das mulheres como uma conquista deste movimento, contudo, vivenciada de formas diferenciadas, levando em consideração as suas trajetórias de vida e suas experiências ideológicas e de que forma isso se repercute no crescente número de mulheres eleitas, representando um projeto conservador. Palavras-chave: Mulher, política, feminismo, antifeminismo
Analysis of the Patient-Physician Relationship, Race, and Pain Control and Physical Function Among Adults With Chronic Low Back Pain
Authors: Licciardone John C. , Ganta Sweta , Goehring Leah , Wallace Kendall , Pu Ryan 
Published: June 2022

ImportanceRacial and ethnic disparities in pain outcomes are widely reported in the United States. However, the impact of the patient-physician relationship on such outcomes remains unclear.ObjectiveTo determine whether the patient-physician relationship mediates the association of race with pain outcomes.Design, Setting, and ParticipantsThis cross-sectional study uses data from the Pain Registry for Epidemiological, Clinical, and Interventional Studies and Innovation, collected from April 2016 to December 2021. All registry enrollees who identified as Black or White with chronic low back pain who had a regular physician who provided pain care were included. Data were analyzed during December 2021.ExposuresParticipant-reported aspects of their patient-physician relationship, including physician communication, physician empathy, and satisfaction with physician encounters.Main Outcomes and MeasuresThe primary outcomes included low back pain intensity, measured with a numerical rating scale and physical function, measured with the Roland-Morris Disability Questionnaire. Mediator variables were derived from the Communication Behavior Questionnaire, Consultation and Relational Empathy measure, and Patient Satisfaction Questionnaire.ResultsAmong 1177 participants, the mean (SD) age was 53.5 (13.1) years, and there were 876 (74.4%) women. A total of 217 participants (18.4%) were Black, and 960 participants (81.6%) were White. The only difference between Black and White participants in the patient-physician relationship involved effective and open physician communication, which favored Black participants (mean communication score, 72.1 [95% CI, 68.8-75.4] vs 67.9 [95% CI, 66.2-69.6]; P = .03). Black participants, compared with White participants reported worse outcomes for pain intensity (mean pain score, 7.1 [95% CI, 6.8-7.3] vs 5.8 [95% CI, 5.7-6.0]; P &amp;lt; .001) and back-related disability (mean disability score, 15.8 [95% CI, 15.1-16.6] vs 14.1 [95% CI, 13.8-14.5]; P &amp;lt; .001). In mediation analyses that controlled for potential confounders using disease risk scores, virtually none of the associations of race with each outcome was mediated by the individual or combined factors of physician communication, physician empathy, and patient satisfaction. Similarly, no mediation was observed in sensitivity analyses that included only participants with both chronic low back pain and the same treating physician for more than 5 years.Conclusions and RelevanceThese findings suggest that factors other than the patient-physician relationship were important to pain disparities experienced by Black participants. Additional research on systemic factors, such as access to high-quality medical care, may be helpful in identifying more promising approaches to mitigating racial pain disparities.
Effect of Virtual Reality on Pain Management and Opioid Use Among Hospitalized Patients After Head and Neck Surgery
Authors: Pandrangi Vivek C. , Shah Suparna N. , Bruening Jennifer D. , Wax Mark K. , Clayburgh Daniel , Andersen Peter E. , Li Ryan J. 
Published: June 2022

ImportanceOptimal postoperative pain management is challenging. Virtual reality (VR) provides immersive, 3-dimensional experiences that may improve pain control and reduce reliance on pharmacologic pain management.ObjectiveTo evaluate use of VR on postoperative pain management after head and neck surgery.Design, Setting, and ParticipantsThis prospective, pilot randomized clinical trial was conducted at Oregon Health &amp; Science University from July 2020 to October 2021 and included patients hospitalized after major head and neck surgery.InterventionsSimilar 15-minute interactive gaming experiences (Angry Birds) using an Oculus Quest VR headset (VR intervention) or a handheld smartphone device (control).Main Outcomes and MeasuresThe primary outcome was postintervention pain reduction. Pain scores were obtained preintervention, immediately after intervention, and then hourly for 4 hours. Secondary outcomes included changes in opioid use, measured as milligram morphine equivalents (MMEs), and patient experiences with their intervention using 5-point Likert scales.ResultsOf the 30 patients randomized for inclusion, the final population included 14 patients in the VR cohort and 15 patients in the control cohort; the majority of patients were male (26 of 29 [90%]), and the mean (SD) age was 58.3 (13.8) years. After outlier removal, there were clinically meaningful reductions in postintervention pain among patients in the VR group immediately after intervention (mean difference, −1.42; 95% CI, −2.15 to −0.70; d = 1.50), at 1 hour (mean difference, −0.86; 95% CI, −1.90 to 0.14; d = 0.67), 2 hours (mean difference, −1.07; 95% CI, −2.30 to 0.14; d = 0.69), and 3 hours (mean difference, −1.36; 95% CI, −2.80 to 0.13; d = 0.71) compared with patients in the control group. Patients in the VR group also demonstrated reductions in 4-hour postintervention opioid use compared with 4-hour preintervention opioid use (mean difference, −9.10 MME; 95% CI, −15.00 to −1.27 MME; d = 0.90) and 8-hour postintervention opioid use compared with 8-hour preintervention opioid use (mean difference, −14.00 MME; 95% CI, −25.60 to −2.40 MME; d = 0.94). There were no meaningful differences in subjective patient experiences with their respective interventions.Conclusions and RelevanceIn this randomized clinical trial, VR reduced pain scores and opioid use compared with a control intervention. Virtual reality may be a useful adjunct for postoperative pain management after head and neck surgery.Trial RegistrationClinicalTrials.gov Identifier: NCT04464304
A Multimodal Prediction Model for Diagnosing Pulmonary Hypertension in Systemic Sclerosis
Authors: Lui Justin K. , Gillmeyer Kari R. , Sangani Ruchika A. , Smyth Robert J. , Gopal Deepa M. , Trojanowski Marcin A. , Bujor Andreea M. , Soylemez Wiener Renda , LaValley Michael P. , Klings Elizabeth S. 
Published: June 2022

ObjectiveDiagnosis of pulmonary hypertension (PH) in systemic sclerosis (SSc) requires an invasive right heart catheterization (RHC), often based on an elevated estimated pulmonary artery systolic pressure on screening echocardiography. However, because of the poor specificity of echocardiography, a greater number of patients undergo RHC than necessary, exposing patients to potentially avoidable complication risks. The development of improved prediction models for PH in SSc may inform decision‐making for RHC in these patients.MethodsWe conducted a retrospective study of 130 patients with SSc; 66 (50.8%) were diagnosed with PH by RHC. We used data from pulmonary function testing, electrocardiography, echocardiography, and computed tomography to identify and compare the performance characteristics of 3 models predicting the presence of PH: 1) random forest, 2) classification and regression tree, and 3) logistic regression. For each model, we generated receiver operating curves and calculated sensitivity and specificity. We internally validated models using a train‐test split of the data.ResultsThe random forest model performed best with an area under the curve of 0.92 (95% confidence interval [95% CI] 0.83–1.00), sensitivity of 0.95 (95% CI 0.75–1.00), and specificity of 0.80 (95% CI 0.56–0.94). The 2 most important variables in our random forest model were pulmonary artery diameter on chest computed tomography and diffusing capacity for carbon monoxide on pulmonary function testing.ConclusionsIn patients with SSc, a random forest model can aid in the detection of PH with high sensitivity and specificity and may allow for better patient selection for RHC, thereby minimizing patient risk.
Single‐Atom‐Regulated Heterostructure of Binary Nanosheets to Enable Dendrite‐Free and Kinetics‐Enhanced Li–S Batteries
Authors: Zhou Chao , Li Ming , Hu Nantao , Yang Jianhua , Li Hong , Yan Jiawei , Lei Puyi , Zhuang Yunpeng , Guo Shouwu 
Published: June 2022

AbstractHeterostructures show potential as electrodes/functionalized separators for lithium‐sulfur (Li‐S) batteries owing to their remarkable electroactive and structural stability. Yet, the heterostructures with unique structures as well as the regulation of heterointerface electronic structure are still challenging for high‐performance Li–S batteries. Herein, Pt single‐atoms (SAs)‐regulated heterostructures of In2S3/Ti3C2 binary nanosheets (Pt SAs/In2S3/Ti3C2) are facilely constructed via an ultrasound‐assisted photochemical reduction strategy for dendrite‐free and kinetics‐enhanced Li–S batteries. The as‐designed heterostructures of Pt SAs/In2S3/Ti3C2 on separator can stabilize the Li plating/striping on Li anodes even at a high current density of 5 mA cm−2. In addition, Pt SAs/In2S3/Ti3C2 heterostructure can suppress the polysulfide shuttling and exhibit excellent redox electrocatalytic properties for lithium polysulfides decomposition. The batteries with heterostructure‐modified separators show a high initial discharge capacity of 1068.4 mAh g−1 at 0.5 C, excellent rate performances (719.6 mAh g−1 at 5C), and a remarkable cycling ability. Even with a high sulfur loading of 6.4 mg cm−2, the pouch cell can deliver an areal capacity of 5.54 mAh cm−2 at 0.2 C. This work not only provides a new route for preparing SA‐catalysts, but also sheds new lights into engineering electronic structures of heterointerfaces for developing high‐performance Li–S batteries.
Enhancement of Lymphangiogenesis by Human Mesenchymal Stem Cell Sheet
Authors: Jia Wenkai , He Weilue , Wang Guifang , Goldman Jeremy , Zhao Feng 
Published: June 2022

AbstractPreparation of human mesenchymal stem cell (hMSC) suspension for lymphedema treatment relies on conventional enzymatic digestion methods, which severely disrupts cell–cell and cell–extracellular matrix (ECM) connections, and drastically impairs cell retention and engraftment after transplantation. The objective of the present study is to evaluate the ability of hMSC‐secreted ECM to augment lymphangiogenesis by using an in vitro coculturing model of hMSC sheets with lymphatic endothelial cells (LECs) and an in vivo mouse tail lymphedema model. Results demonstrate that the hMSC‐secreted ECM augments the formation of lymphatic capillary‐like structure by a factor of 1.2–3.6 relative to the hMSC control group, by serving as a prolymphangiogenic growth factor reservoir and facilitating cell regenerative activities. hMSC‐derived ECM enhances MMP‐2 mediated matrix remodeling, increases the synthesis of collagen IV and laminin, and promotes lymphatic microvessel‐like structure formation. The injection of rat MSC sheet fragments into a mouse tail lymphedema model confirms the benefits of the hMSC‐derived ECM by stimulating lymphangiogenesis and wound closure.
Biofabrication of Multiplexed Electrochemical Immunosensors for Simultaneous Detection of Clinical Biomarkers in Complex Fluids
Authors: Timilsina Sanjay S. , Ramasamy Mohanraj , Durr Nolan , Ahmad Rushdy , Jolly Pawan , Ingber Donald E. 
Published: June 2022

AbstractSimultaneous detection of multiple disease biomarkers in unprocessed whole blood is considered the gold standard for accurate clinical diagnosis. Here, this study reports the development of a 4‐plex electrochemical (EC) immunosensor with on‐chip negative control capable of detecting a range of biomarkers in small volumes (15 µL) of complex biological fluids, including serum, plasma, and whole blood. A framework for fabricating and optimizing multiplexed sandwich immunoassays is presented that is enabled by use of EC sensor chips coated with an ultra‐selective, antifouling, and nanocomposite coating. Cyclic voltammetry evaluation of sensor performance is carried out by monitoring the local precipitation of an electroactive product generated by horseradish peroxidase linked to a secondary antibody. EC immunosensors demonstrate high sensitivity and specificity without background signal with a limit of detection in single‐digit picogram per milliliter in multiple complex biological fluids. These multiplexed immunosensors enable the simultaneous detection of four different biomarkers in plasma and whole blood with excellent sensitivity and selectivity. This rapid and cost‐effective biosensor platform can be further adapted for use with different high affinity probes for any biomarker, and thereby create for a new class of highly sensitive and specific multiplexed diagnostics.