bluuebunny/crossref_metadata_2025_split huggingface dataset:
Empirical evidence of the relationship between terrorism and firm financial performance in Nigeria
Authors: Okafor Godwin , Calderon Camilo 
Published: May 2022

PurposeThis paper investigates the relationship between terrorism and firm financial performance in Nigeria. The country has become one of the riskiest countries in Sub-Saharan Africa due to the intensity of recent terror attacks. Also, there is a growing focus on the importance of firms, given firms' economic contribution towards growth, employment and economic and industrial transformation. However, no study has tried establishing a relationship between terrorism and firm financial performance. Therefore, providing empirical proof of this relationship is the primary purpose and motivation of this paper.Design/methodology/approachData from the World Bank Enterprise Survey (WBES) and the Global Terrorism Database (GTD) were used for this study. The baseline analysis was estimated using the pooled ordinary least squares regression technique. For robustness checks, the fixed effects technique was used to control for heterogeneity across the authors' sample of firms and unobserved factors that are time-invariant, while the IV technique was employed to control for any potential endogeneity.FindingsThe results obtained from the regression analysis were robust to different econometric estimations and approaches. Terrorism was found to have a consistent and significant negative impact on firm financial performance. Furthermore, the marginal effect of terrorism on firm performance was more substantial when state-level terrorism data were used.Originality/valueStudies often focus on the impact of political instability (which is a measure subjectively based on perception) on foreign direct investment or on the activities of multinational corporations. The authors' research is new in supplying evidence of the relationship between terrorism (an objective measure) and the financial performance of manufacturing firms in Nigeria. Methodologically, this study also employed spatially distributed incidents of terrorism within the country. This is because incidents of terrorism are often spatially distributed within a country (i.e. province or state). This will provide new evidence of the effects of within-country variations of terrorism on firm financial performance.
Can intelligent manufacturing empower manufacturing? – an empirical study considering ambidextrous capabilities
Authors: Lu Na , Zhou Wei , Dou Zhi Wu 
Published: May 2022

PurposeIntelligent manufacturing has attracted extensive attention from national strategy, academic research and enterprises' practices. The purpose of this study is to investigate the influence of intelligent manufacturing on performance in manufacturing firms. Moreover, how intelligent manufacturing technology affects enterprise performance, this study provided a practice that can be replicated by other businesses.Design/methodology/approachThis study uses text mining to collect the intelligence level of Chinese listed companies. It uses quantitative analysis to test the proposed model based on samples of 2,091 manufacturers.FindingsIntelligent manufacturing has positive effect on short-term performance and long-term performance. Intelligent manufacturing can empower firms with ambidextrous capabilities, including exploit capability and explore capability. Exploit capability has positive effects on short-term performance and long-term performance. Explore capability has negative effects on short-term performance, but has positive effects on long-term performance.Originality/valueOn the theoretical side, it enriches the research framework between intelligent manufacturing and enterprise performance. This study explains the preconditions and results of ambidextrous capabilities. Moreover, based on the practice-based view (PBV), this study proposes that technologies can be used as strategies, filling a gap in the existing research on strategic management. On the practical side, how to quantify the intelligent manufacturing level of enterprises provides a certain reference. Also, this study provides an easy to imitate practice that can serve as a model for under-performing enterprises.
Examining the status of IPSAS adoption at the country level: an analysis of the OECD member states
Authors: Bekiaris Michalis , Paraponti Thekla 
Published: May 2022

Purpose
The purpose of this study is to provide an overview of the adoption status of International Public Sector Accounting Standards (IPSAS) within Organisation for Economic Co-operation and Development (OECD) member states at the country level and highlight the main factors impeding the process of accounting harmonisation.

Design/methodology/approach
This study uses factor analysis (FA) to assess the status of IPSAS adoption as the weighted average of the adoption levels of three categories: central government, sub-national governments, and country-level consolidation. Based on this assessment, the sample is classified into three levels of IPSAS adoption: high, medium, and low.

Findings
The findings suggest a slow trend towards accounting harmonisation and an increasing influence of IPSAS. However, evidence also suggests significant limitations in the adoption of the standards, mainly attributed to national adaptations, which undermine the ongoing efforts for standardisation.

Originality/value
This study provides an integrated view of IPSAS adoption at the country level and sheds light on a different aspect of the international harmonisation process, which is missing from the literature.
Effects of human capital on entrepreneurial ecosystems in the emerging economy: the mediating role of digital knowledge and innovative capability from India perspective
Authors: Chaudhuri Ranjan , Chatterjee Sheshadri , Vrontis Prof. Demetris , Vicentini Francesca 
Published: May 2022

PurposeThis study empirically examines the relationship between human capital ecosystems and entrepreneurial ecosystems. The study also investigates the mediating roles of digital knowledge capability and innovation capability and the moderating role of technology turbulence in the entrepreneurial ecosystem.Design/methodology/approachThe study takes inputs from existing literature and resource-based view (RBV) and absorptive capacity theories and develops a theoretical model. Later, the model is validated using the structural equation modeling technique with data collected from India-based startup enterprises.FindingsThe authors found a nexus between human capital and entrepreneurial ecosystems. The study also highlights that enterprises' digital knowledge capability and innovation capability significantly influence the entrepreneurial ecosystem. The study also found that technology turbulence has a significant moderating impact on the relationship between digital knowledge capability and innovation capability in entrepreneurial ecosystems.Research limitations/implicationsThe study shows the importance of developing human capital for improving enterprises' innovation capability and digital knowledge capability, which are also important to develop the entrepreneurial ecosystem. Entrepreneurs can use the proposed model in their enterprises for appropriately developing the entrepreneurial ecosystem.Originality/valueThe authors propose a theoretical model for entrepreneurial ecosystems, from the human capital perspective, which entrepreneurs could use to improve the overall organizational performance. Moreover, the model uses technology turbulence as a moderator, which is also a novel approach. The study also adds valuable knowledge to the overall body of literature of intellectual capital.
Intraspecific trait changes in response to drought lead to trait convergence between—but not within—species
Authors: Rodríguez‐Alarcón Slendy , Tamme Riin , Carmona Carlos P. 
Published: May 2022

Abstract

Drought is expected to increase in future climate scenarios. Although responses to drought of individual functional traits are relatively well‐known, simultaneous changes across multiple traits in response to water scarcity remain poorly understood despite its importance to understand alternative strategies to resist drought.

We grew 52 herbaceous species in monocultures under drought and control treatments and characterized the functional space using seven measured above‐ and below‐ground traits: plant height, leaf area, specific leaf area, leaf dry matter content, specific root length, average root diameter, and root dry matter content. Then, we estimated how each species occupied this space and the amount of functional space occupied in both treatments using trait probability density functions. We also estimated intraspecific trait variability (ITV) for each species as the dissimilarity in trait values between the individuals of each treatment. We then mapped drought resistance and ITV in the functional space using generalized additive models.

The response of species to drought strongly depended on their traits, with species that invested more in root tissues and conserved small size being both more resistant to drought and having higher ITV. We also observed a significant trend of trait displacement towards less conservative strategies. However, these changes depended strongly on the trait values of species in the control treatment, with species with different traits having opposing responses to drought. These contrasting responses resulted in lower trait variability in the species pool in drought compared to control conditions. Our results suggest strong trait filtering acting on conservative species as well as the existence of an optimal part in the functional space to which species converge under drought.

Our results show that changes in species trait‐space occupancy are key to understand plant strategies to withstand drought, highlighting the importance of individual variation in response to environmental changes, and suggest that community‐wide functional diversity and biomass productivity could decrease in a drier future. Knowing these shifts will help to anticipate changes in ecosystem functioning facing climate change.

Read the free Plain Language Summary for this article on the Journal blog.
Post‐translational modifications drive secondary metabolite biosynthesis in Aspergillus: a review
Authors: Yang Kunlong , Tian Jun , Keller Nancy P. 
Published: May 2022

SummaryPost‐translational modifications (PTMs) are important for protein function and regulate multiple cellular processes and secondary metabolites (SMs) in fungi. Aspergillus species belong to a genus renown for an abundance of bioactive secondary metabolites, many important as toxins, pharmaceuticals and in industrial production. The genes required for secondary metabolites are typically co‐localized in biosynthetic gene clusters (BGCs), which often localize in heterochromatic regions of genome and are ‘turned off’ under laboratory condition. Efforts have been made to ‘turn on’ these BGCs by genetic manipulation of histone modifications, which could convert the heterochromatic structure to euchromatin. Additionally, non‐histone PTMs also play critical roles in the regulation of secondary metabolism. In this review, we collate the known roles of epigenetic and PTMs on Aspergillus SM production. We also summarize the proteomics approaches and bioinformatics tools for PTM identification and prediction and provide future perspectives on the emerging roles of PTM on regulation of SM biosynthesis in Aspergillus and other fungi.
Muting Science: Input Overload Versus Scientific Advice in Swiss Policy Making During the Covid‐19 Pandemic
Authors: Armingeon Klaus , Sager Fritz 
Published: May 2022

AbstractThis article explores why the Swiss Federal Council and the Swiss Federal Parliament were reluctant to follow the majority views of the scientific epidemiological community at the beginning of the second wave of the Covid‐19 pandemic. We propose an institutionalist take on this question and argue that one major explanation could be the input overload that is characteristic of the Swiss federal political system. We define input overload as the simultaneous inputs of corporatist, pluralist, federalist and direct democratic subsystems. Adding another major input—this time from the scientific subsystem—may have threatened to further erode the government's and parliament's discretionary power to cope with the pandemic. We assume that the federal government reduced its input overload by fending off scientific advice.
Iodinated contrast media shortage: Insights and guidance from two major public hospitals
Authors: Amukotuwa Shalini A , Bammer Roland , Jackson Dana M , Sutherland Thomas 
Published: May 2022

SummaryGlobal shortage of iodinated contrast medium (ICM) is the latest health care ripple‐effect from the COVID‐19 pandemic. Some public hospitals in Australia have less than a week's supply. Strategies are, therefore, urgently needed to conserve ICM for those diagnostic tests and interventions, which are time‐critical, and without which patients would suffer death or significant morbidity. A plan is also required to continue providing best possible care to patients in the worst‐case scenario of exhausted ICM supplies. This document, by representatives from two major public hospitals, will provide some guidance that is tailored to the Australian context.
Social media information dissemination and corporate bad news hoarding
Authors: He Feng , Feng Yaqian , Feng Lingbing 
Published: May 2022

AbstractThis paper investigates the role of social media in mitigating corporate bad news hoarding from a stock price crash risk perspective. Using a sample of public listed firms from 2008–2019, we find that social media (Guba) posts could significantly reduce firms’ stock price crash risks in the Chinese stock market. Furthermore, we find that the information intermediation function and complementary corporate governance function enable Guba to achieve such an effect. In addition, investor attention mediates the relationship between Guba posts and management withholding bad news. Our result still holds after a series of robustness checks, including an RDD approach.
Surgical management of a lateral lesion refractory to root canal retreatment caused by an extraradicular calculus. A case report
Authors: Ricucci Domenico , Milovidova Irina , Rôças Isabela N. , Siqueira José F. 
Published: May 2022

AbstractThis article describes the management of a root canal‐treated maxillary central incisor displaying a radiographic lateral radiolucency and a sinus tract that persisted irrespective of root canal retreatment following high standards. Endodontic microsurgery was indicated and curettage of the pathologic tissue revealed a calculus‐like material attached to the outer root surface around the exit of a large lateral canal. A non‐conventional approach was chosen: No root‐end resection was conducted. Instead, the calculus was removed and the apical surface was scaled and smoothed, conserving the apical structure. Retrocavities were prepared in both lateral and apical foramens and filled with a bioceramic material. Follow‐up examination showed optimal soft tissue healing. One‐year follow‐up of radiographs revealed healing of the lateral lesion. The lesion was diagnosed as a cyst, with an infected lumen. An exuberant calculus‐like material attached to the external root surface was the most likely cause of the recalcitrant lateral periradicular lesion.
The TNNT2:c.95‐108G>A variant is common in Maine Coons and shows no association with hypertrophic cardiomyopathy
Authors: Schipper Tom , Ohlsson Åsa , Longeri Maria , Hayward Jessica J. , Mouttham Lara , Ferrari Paolo , Smets Pascale , Ljungvall Ingrid , Häggström Jens , Stern Joshua A. , Lyons Leslie A. , Peelman Luc J. , Broeckx Bart J. G. 
Published: May 2022

AbstractHypertrophic cardiomyopathy (HCM) is a common and potentially fatal heart disease in many cat breeds. An intronic variant in TNNT2, c.95‐108G>A, was recently reported as the cause of HCM in the Maine Coon. The aim of this study was to determine this variant’s allele frequency in different populations and its possible association with HCM. Based on 160 Maine Coon samples collected in Belgium, Italy, Sweden and the USA, the variant’s allele frequency was estimated to be 0.32. Analysis of the 99 Lives feline whole genome sequencing database showed that the TNNT2 variant also occurs in other breeds, as well as mixed‐breed cats. Comparison of 31 affected and 58 healthy cats did not reveal significantly increased odds for HCM in homozygotes. Based on the combined evidence and in agreement with the standards and guidelines for the interpretation of sequence variants, this variant is currently classified as a variant of unknown significance and should not be used for breeding decisions regarding HCM.
Clustering trends of melanoma incidence and mortality: A worldwide assessment from 1995 to 2019
Authors: Ahmadi Farzane , Karamitanha Farzaneh , Ramezanpour Afshar 
Published: May 2022

AbstractBackgroundMelanoma is a skin cancer that has higher mortality among cutaneous malignant tumours. Tumour incidence in most world regions is rising. Here, we intend to highlight these trends in the world.MethodsWe used the global burden of disease dataset to assess the incidence and mortality of melanoma from 1995 to 2019 in 204 countries/territories. To identify country/territory groups with similar trends of melanoma incidence and mortality, a model‐based clustering with a mixture of multivariate t‐distributions was used.ResultsAustralia and New Zealand had the largest incidence and mortality rates. Men in Egypt and women in Sri Lanka and Guam had the lowest incidence and mortality rates. The clustering analysis revealed 4 classes of incidence in both gender and 3 and 2 classes of mortality in male and female, respectively. All groups had a growing incidence rate in both gender, similar to the worldwide trend. In 10% of the countries/territories, central and Western Europe, the incidence increase rate was greater than in the countries/territories with the greatest incidence. The total mortality rate for men was steadily growing, although it was decreasing in Asian and African countries/territories. Overall, the mortality rate for women remained relatively steady over time.ConclusionDue to the increasing trend of melanoma in the world, primary and secondary prevention of this disease, especially in areas with higher incidence and mortality, is essential. Raising awareness about the disease is helpful in prevention and early detection of melanoma.
Platelet count and plateletcrit: Potential haematological biomarkers for livedoid vasculopathy?
Authors: Gao Yimeng , Jin Hongzhong 
Published: May 2022

AbstractBackgroundThe pathogenesis of livedoid vasculopathy (LV) remains unknown. Although platelet activation occurs in LV, little research has been conducted on LV platelet morphology parameters. The purpose of this study was to investigate whether platelet morphology changes in LV and its clinical significance.MethodsTwenty‐seven LV patients and 21 cutaneous small vessel vasculitis (CSVV) patients, all at the active stage, were included. Platelet parameters in active‐ and stable‐stage LV and CSVV patients were compared. Correlations between these platelet parameters and LV composite clinical scores were analysed.ResultsLV patients' mean age was 25.48 years (range: 9–62 years), and 81.48% (22/27) were women and 18.52% (5/27) were men. The platelet counts and plateletcrit (PCT) levels were significantly elevated in LV patients compared with CSVV patients and in active‐stage LV patients compared with stable‐stage LV patients after treatment. LV patient composite clinical scores that reflected disease severity and activity were positively correlated with the platelet count and PCT levels.ConclusionAltered platelet morphology was detected in LV patients. Platelet count and PCT might be haematological biomarkers for early prediction of LV activity and relapses and for differential identification between LV and CSVV.
Effect of season on slaughter performance, meat quality, muscle amino acid and fatty acid composition, and metabolism of pheasants (Phasianus colchicus)
Authors: Liang Fangfang , Yan Lei , Li Yumei , Jin Yongcheng , Zhang Jing , Che Haoyu , Diao Jizhe , Gao Yequn , He Zhaolan , Sun Ruihong , He Yuntong , Zhou Changhai 
Published: May 2022

AbstractThis study aimed to investigate the effect of summer and winter on slaughter performance, muscle quality, flavor‐related substance content, and gene expression levels related to the fat metabolism of pheasants. One‐hundred 1‐day‐old pheasants were fed for 5 months starting in March and July and then, respectively, slaughtered in summer (August) and winter (December). The results revealed that compared with summer, winter not only increased pheasant live weight, dressed percentage, full‐eviscerated yield, and muscle yield (p < 0.05) but also enhanced the activities of SOD and CAT in serum (p < 0.05). Winter significantly increased meat color, the contents of inosinic acid, and flavor amino acid in muscle. Amino acid contents in leg muscles of pheasants in winter were significantly higher than in summer except for histidine (p < 0.05). Winter increased the contents of muscle mono‐unsaturated fatty acid, reducing saturated fatty acid. Summer improved fat synthesis in liver, promoted the deposition of triglycerides and cholesterol, and reduced the expression levels of fat metabolism‐related genes in muscle, while winter increased the expression levels of genes related to muscle fat metabolism to provide energy for body and affect muscle fatty acid profile. Overall, pheasants fed in winter had better sensory quality and flavor than summer.
Association between ticagrelor plasma concentration and bleeding events in Chinese patients with acute coronary syndrome
Authors: Yang Jing , Qi Guangzhao , Hu Fudong , Zhang Xiaojian , Xing Yu , Wang Peile 
Published: May 2022

AimsThe risk of ticagrelor‐related bleeding events remains a major clinical concern, especially in East Asian populations. Previous studies have reported higher ticagrelor exposure in Asian patients than in Caucasians. This prompted us to investigate the correlation between ticagrelor concentrations and bleeding events.MethodsPatients diagnosed with acute coronary syndrome and receiving dual antiplatelet therapy (aspirin and ticagrelor) were enrolled and followed up for 12 months. Trough plasma concentrations of ticagrelor and a major active metabolite were assayed, and 10 single nucleotide polymorphisms associated with ticagrelor pharmacokinetics and safety were also identified.ResultsA total of 631 patients were included and 133 patients had bleeding academic research consortium type 1 or 2 bleeding event. The median ticagrelor concentration (interquartile range) was significantly higher in patients with bleeding events than that in patients without bleeding events (322.6 ng/mL [196.2–458.0 ng/mL] vs. 222.1 ng/mL [140.4–341.9 ng/mL], P < .001). According to the receiver operating characteristic curve, the cut‐off value for ticagrelor levels predicting bleeding events was 363.3 ng/mL (area under the curve = 0.65; P < .001, 95% Cl: 0.595–0.700). Pharmacogenomics results showed that P2Y12 (rs6787801, P = .024) and P2Y12 (rs6785930, P = .048) were statistically associated with ticagrelor levels and bleeding events, respectively.ConclusionTicagrelor plasma concentrations were associated with bleeding events in Chinese patients with acute coronary syndrome.