bluuebunny/crossref_metadata_2025_split huggingface dataset:
Negative regulation of root-knot nematode parasitic behavior by root-derived volatiles of wild relatives of Cucumis metuliferus CM3
Authors: Xie Xiaoxiao , Ling Jian , Mao Zhenchuan , Li Yan , Zhao Jianlong , Yang Yuhong , Li Yanlin , Liu Mingyue , Gu Xingfang , Xie Bingyan 
Published: February 2022

Abstract
Root-knot nematodes (RKN; Meloidogyne spp.) cause a significant decrease in the yield of cucumber crops every year. Cucumis metuliferus is an important wild germplasm that has resistance to RKN in which plant root volatiles are thought to play a role. However, the underlying molecular mechanism is unclear. To investigate it, we used the resistant C. metuliferus line CM3 and the susceptible cucumber line Xintaimici (XTMC). CM3 roots repelled Meloidogyne incognita second-stage larvae (J2s), while the roots of XTMC plants attracted the larvae. CM3 and XTMC were found to contain similar amounts of root volatiles, but many volatiles, including nine hydrocarbons, three alcohols, two aldehydes, two ketones, one ester, and one phenol, were only detected in CM3 roots. It was found that one of these, (methoxymethyl)-benzene, could repel M. incognita, while creosol and (Z)-2-penten-1-ol could attract M. incognita. Interestingly, creosol and (Z)-2-penten-1-ol effectively killed M. incognita at high concentrations. Furthermore, we found that a mixture of CM3 root volatiles increased cucumber resistance to M. incognita. The results provide insights into the interaction between the host and plant-parasitic nematodes in the soil, with some compounds possibly acting as nematode biofumigation, which can be used to manage nematodes.
The effect of technology and regulation on the co-evolution of product and industry architecture
Authors: Burton Nicholas , Galvin Peter 
Published: February 2022

AbstractThis paper explores the co-evolution of product and industry architecture by drawing on a longitudinal study of the UK personal pensions industry between 2005 and 2020. It provides qualitative evidence for the way in which institutional structures, particularly regulation, entwine with firm strategic choices to shape the contours of an industry value chain (IVC). We draw upon modularity theory and the literature on industry architecture to consider how strategic bottlenecks emerged and how value shifted between layers of the IVC. Furthermore, we examine the interplay between the agendas of the regulator and firm strategic responses to unpack how firms (product providers) responded by pursuing integrative innovation and less specialization to mitigate the effects of value migration to strategic bottlenecks. Our findings extend recent work on product and industry architecture, highlighting how markets evolve toward less modular product configurations and less industry specialization in response to these dynamics.
The role of behavioural variation in the success of artisanal fishers who interact with dolphins
Authors: Valle-Pereira João V S , Cantor Mauricio , Machado Alexandre M S , Farine Damien R , Daura-Jorge Fábio G 
Published: February 2022

Abstract
Understanding the dynamics of small-scale fisheries requires considering the diversity of behaviours and skills of fishers. Fishers may have different abilities and tactics that can translate into different fishing outcomes. Here, we investigate variation in fishing behaviours among traditional net-casting fishers that are assisted by wild dolphins, and how this variation interacts with environmental conditions and influences fishing success. By combining in situ environmental sampling with fine-scale behavioural tracking from overhead videos, we found a higher probability of catching fish among fishers well-positioned in the water and that cast their nets wide-open and closer to dolphins. These differences in net-casting performance affect their chance of catching any fish over and above environmental conditions related to fish availability. This finding suggests that fishers’ success may not be simply an outcome of variations in resource availability, but also result from subtle variations in fishing behaviours. We discuss how such behavioural variations can represent skills acquired over the years, and how such skills can be crucial for fishers to benefit and keep interacting with dolphins. Our study demonstrates the role of behavioural variation in the dynamics of a century-old fishery and highlights the need to consider fishers’ behaviours in co-management of small-scale fisheries.
Long-duration transit and food and water deprivation alter behavioral activities and aggressive interactions at the feed bunk in beef feedlot steers
Authors: Heiderscheit Katie J , Freestone Alyssa D , Beenken Aubree M , Deters Erin L , Peschel Joshua M , Hansen Stephanie L 
Published: February 2022

Abstract
The objective of these experiments was to assess the effects of food and water deprivation and transit duration on the behavior of beef feedlot steers. In Experiment 1, 36 Angus-cross steers (353 ± 10 kg) were stratified to 6 pens and assigned one of three treatments (n = 12 steers per treatment): control (CON; stayed in home pens with ad libitum access to feed and water), deprived (DEPR; stayed in home pens but deprived of feed and water for 18 h), or transported (TRANS; subjected to 18-h transit event and returned to home pens). In Experiment 2, 60 Angus-cross steers (398 ± 5 kg; 6 steers per pen) were transported either 8 (8H) or 18 (18H) h. Four 8H pens (n = 24 steers) and six 18H pens (n = 36 steers) were used for behavioral analysis. In both experiments, the time to eat, drink, and lay down was recorded for each steer upon return to home pens. Total pen displacements from the feed bunk were also assessed for the 2 h following feed access in both experiments. Data were analyzed using Proc Mixed of SAS 9.4, with treatment as a fixed effect. Steer was the experimental unit for behavioral activities, while pen was the experimental unit for bunk displacements. Displacements were analyzed as repeated measures with the repeated variable of time. In Experiment 1, the time to eat and drink was similar across treatments (P ≥ 0.17). However, TRANS laid down in 16.5 min while DEPR did not lay down until 70.5 min post-arrival to pen (P &lt; 0.01). Deprived steers had greater bunk displacements in the first 70 min post-feed access than CON or TRANS, though displacements among treatments from 100 to 120 min post-feed access were similar (treatment × time: P = 0.02). In Experiment 2, both 8H and 18H steers laid down approximately 25 min post-home pen arrival (P = 0.14). There was no effect of transit duration or duration by time on bunk displacements (P ≥ 0.20), though displacements were greater from 0 to 20 min than from 20 to 30 min post-feed access (time: P = 0.04). Steers that were deprived of feed and water were highly motivated to access those resources, while transported steers prioritized laying down. Producers should consider these priorities when preparing to receive cattle from a long transit event.
Local grasses for the control of the invasive vine Mikania micrantha
Authors: Zhou Sheng , Wang Min , Yuan Linglong , Chen Hao , Yan Linyuan , Yao Sitong , Zhang Bipei 
Published: February 2022

Abstract
Mikania micrantha (Asteraceae) is an invasive vine found in tropical and southern subtropical Asian and the Pacific Islands. The current methods used to control this vine are inadequate, which warrants the development of ecologically sustainable methods. Therefore, we investigated the ability of four grass species to prevent the invasion of M. micrantha, with an ultimate goal of developing ecologically sustainable control methods for widespread application. The clumps of native grass species from China (Panicum incomtum, Pennisetum purpureum, Saccharum arundinaceum and Microstegium vagans) were established. We sowed M. micrantha seeds and transplanted the seedlings into the grass clumps to examine whether the clumps could eliminate the new M. micrantha plants. In addition, we transplanted M. micrantha into existing grass clumps to examine whether the grass clumps could prevent the re-invasion of M. micrantha. Furthermore, we grew M. micrantha with P. incomtum and P. purpureum in the field to examine whether the grasses could outcompete M. micrantha. Mikania micrantha seeds germinated hardly in the grass clumps, and all seedlings died within 3 months. It was difficult for the vine to survive in the grass clumps. Our field experiments showed that the coverage of M. micrantha was significantly lower than that of the grass species in the first year, and that the vine was outcompeted after 2 years. To the best of our knowledge, this study is the first to reveal that tall grasses, particularly P. incomtum and P. purpureum, have potential to serve as bio-control agents for M. micrantha.
Blepharoptosis as a complication of percutaneous ethanol injection of thyroid cyst
Authors: Kitazawa Takeshi , Suito Motomu , Nagaya Hiroyuki 
Published: February 2022

Abstract
Complications of percutaneous ethanol injection (PEI) for thyroid cyst are rare. Almost all complications reported have been transient, including Horner’s syndrome. We provide herein the first description of persistent blepharoptosis subsequent to PEI, necessitating surgical correction. A 54-year-old woman presented to our hospital with left blepharoptosis that had occurred the day after PEI for a thyroid cyst. She showed 2 mm of blepharoptosis and 1 mm of miosis in the left eye compared to the right eye. Magnetic resonance imaging of the brain demonstrated no abnormalities, and computed tomography detected no lesions in the neck or chest other than the already known cyst. Instillation of phenylephrine eye drops allowed elevation of the left upper eyelid. Considering these findings, we diagnosed the blepharoptosis as part of Horner’s syndrome. The ptosis was corrected by levator aponeurosis advancement. No recurrence has been observed as of 9 months postoperatively.
Land snail assemblages and microhabitat preferences in the urban areas of Kolkata, India
Authors: Nandy Gargi , Barman Himangshu , Pramanik Soujita , Banerjee Sampa , Aditya Gautam 
Published: February 2022

AbstractDue to the minimal dispersal capabilities and dependency on particular microhabitat, the land snails are susceptible to anthropogenic and natural disturbances. Considering the increasing anthropogenic threats, especially in urban areas, information on species’ requirements for particular habitat is very essential for land snail conservation and sustenance. In the present commentary, diversity and distribution of small-sized land snails in relation to their microhabitat preference in urban habitats of Kolkata, West Bengal, had been carried out through the quadrat method. The information on the richness and abundance of snails and their habitat places in Kolkata, India, was used to construct a bipartite network. A total of 13 land snail species were linked with 16 microhabitats. The network indices were used to justify the specialist or generalist nature of the snail species in the context of microhabitat preference. The snail species Succinea daucina and Allopeas gracile were observed to be associated with the maximum number of habitats while species strength was highest for S. daucina. The low value of connectance (0.288, &lt;0.5) and niche overlap (0.34), the high value of specialization index H2′ (0.58) and d′ (0.44) indicate that the snail–microhabitat interactions were highly specialized. The network ecology of snail–microhabitats illustrated in the present instance will enable the identification of preferred microhabitats, which are required for the enhancement of the population of land snails in urban areas like Kolkata, India.
Two wrongs make a right: heat stress reversion of a male-sterile Brassica napus line
Authors: Schuhmann Petra , Engstler Carina , Klöpfer Kai , Gügel Irene L , Abbadi Amine , Dreyer Felix , Leckband Gunhild , Bölter Bettina , Hagn Franz , Soll Jürgen , Carrie Chris 
Published: February 2022

Abstract
Male-sterile lines play important roles in plant breeding to obtain hybrid vigour. The male sterility Lembke (MSL) system is a thermosensitive genic male sterility system of Brassica napus and is one of the main systems used in European rapeseed breeding. Interestingly, the MSL system shows high similarity to the 9012AB breeding system from China, including the ability to revert to fertile in high temperature conditions. Here we demonstrate that the MSL system is regulated by the same restorer of fertility gene BnaC9-Tic40 as the 9012AB system, which is related to the translocon at the inner envelope membrane of chloroplasts 40 (TIC40) from Arabidopsis. The male sterility gene of the MSL system was also identified to encode a chloroplast-localized protein which we call BnChimera; this gene shows high sequence similarity to the sterility gene previously described for the 9012AB system. For the first time, a direct protein interaction between BnaC9-Tic40 and the BnChimera could be demonstrated. In addition, we identify the corresponding amino acids that mediate this interaction and suggest how BnaC9-Tic40 acts as the restorer of fertility. Using an RNA-seq approach, the effects of heat treatment on the male fertility restoration of the C545 MSL system line were investigated. These data demonstrate that many pollen developmental pathways are affected by higher temperatures. It is hypothesized that heat stress reverses the male sterility via a combination of slower production of cell wall precursors in plastids and a slower flower development, which ultimately results in fertile pollen. The potential breeding applications of these results are discussed regarding the use of the MSL system in producing thermotolerant fertile plants.
Basic modal congruent and monotonic multilattice logics
Authors: Grigoriev Oleg , Petrukhin Yaroslav 
Published: February 2022

Abstract
In the paper, we introduce multilattice versions of the basic congruent and monotonic modal logics. In the case of congruent and monotonic ones, we also study their extensions by Gödel’s rule. We formulate these logics in the form of sequent calculi and prove syntactic embedding theorems (as a consequence, we obtain cut admissibility and decidability). Then we present them algebraically and semantically: via modal multilattices and via general and descriptive neighbourhood frames. We show the dual equivalency of the categories of modal multilattices and descriptive neighbourhood frames. Using Lindenbaum–Tarski algebras, we prove that the sequent calculi under consideration are sound and complete with respect to modal multilattices.
Adding creatinine to routine pregnancy tests: a decision tree for calculating the cost of identifying patients with CKD in pregnancy
Authors: Piccoli Giorgina Barbara , Chatrenet Antoine , Cataldo Manuela , Torreggiani Massimo , Attini Rossella , Masturzo Bianca , Cabiddu Gianfranca , Versino Elisabetta ,   Kidney and Pregnancy Study Group of the Italian Society of Nephrology, Santoro Domenico , Moroni Gabriella , Gammaro Linda , Gernone Giuseppe , Covella Bianca 
Published: February 2022

ABSTRACT

Background
Even in its early stages, chronic kidney disease (CKD) is associated with adverse pregnancy outcomes. The current guidelines for pregnancy management suggest identifying risk factors for adverse outcomes but do not mention kidney diseases. Since CKD is often asymptomatic, pregnancy offers a valuable opportunity for diagnosis. The present analysis attempts to quantify the cost of adding serum creatinine to prenatal screening and monitoring tests.

Methods
The decision tree we built takes several screening scenarios (before, during and after pregnancy) into consideration, following the hypothesis that while 1:750 pregnant women are affected by stage 4–5 CKD and 1:375 by stage 3B, only 50% of CKD cases are known. Prevalence of abortions/miscarriages was calculated at 30%; compliance with tests was hypothesized at 50% pre- and post-pregnancy and 90% during pregnancy (30% for miscarriages); the cost of serum creatinine (production cost) was set at 0.20 euros. A downloadable calculator, which makes it possible to adapt these figures to other settings, is available.

Results
The cost per detected CKD case ranged from 111 euros (one test during pregnancy, diagnostic yield 64.8%) to 281.90 euros (one test per trimester, plus one post-pregnancy or miscarriage, diagnostic yield 87.7%). The best policy is identified as one test pre-, one during and one post-pregnancy (191.80 euros, diagnostic yield 89.4%).

Conclusions
This study suggests the feasibility of early CKD diagnosis in pregnancy by adding serum creatinine to routinely performed prenatal tests and offers cost estimates for further discussion.
The bHLH/HLH transcription factors GhFP2 and GhACE1 antagonistically regulate fiber elongation in cotton
Authors: Lu Rui , Li Yang , Zhang Jiao , Wang Yao , Zhang Jie , Li Yu , Zheng Yong , Li Xue-Bao 
Published: February 2022

Abstract
Basic helix–loop–helix/helix–loop–helix (bHLH/HLH) transcription factors play important roles in cell elongation in plants. However, little is known about how bHLH/HLH transcription factors antagonistically regulate fiber elongation in cotton (Gossypium hirsutum). In this study, we report that two bHLH/HLH transcription factors, fiber-related protein 2 (GhFP2) and ACTIVATOR FOR CELL ELONGATION 1 (GhACE1), function in fiber development of cotton. GhFP2 is an atypical bHLH protein without the basic region, and its expression is regulated by brassinosteroid (BR)-related BRASSINAZOLE RESISTANT 1 (GhBZR1). Overexpression of GhFP2 in cotton hindered fiber elongation, resulting in shortened fiber length. In contrast, suppression of GhFP2 expression in cotton promoted fiber development, leading to longer fibers compared with the wild-type. GhFP2 neither contains a DNA-binding domain nor has transcriptional activation activity. Furthermore, we identified GhACE1, a bHLH protein that interacts with GhFP2 and positively regulates fiber elongation. GhACE1 could bind to promoters of plasma membrane intrinsic protein 2;7 (GhPIP2;7) and expansions 8 (GhEXP8) for directly activating their expression, but the interaction between GhFP2 and GhACE1 suppressed transcriptional activation of these target genes by GhACE1. Taken together, our results indicate that GhACE1 promotes fiber elongation by activating expressions of GhPIP2;7 and GhEXP8, but its transcription activation on downstream genes may be obstructed by BR-modulated GhFP2. Thus, our data reveal a key mechanism for fiber cell elongation through a pair of antagonizing HLH/bHLH transcription factors in cotton.
The Individual Placement and Support (IPS) in Pain Trial: A Randomized Controlled Trial of IPS for Patients with Chronic Pain Conditions
Authors: Sveinsdottir Vigdis , Jacobsen Henrik Børsting , Ljosaa Tone Marte , Linnemørken Lene Therese Bergerud , Knutzen Thomas , Ghiasvand Reza , Reme Silje Endresen 
Published: February 2022

Abstract

Objectives
Although complex pain conditions require an interdisciplinary approach, employment services are rarely provided in pain centers. Individual Placement and Support (IPS) is an effective approach to increase work participation among patients with severe mental illness, and recent evidence suggests that this method can be successfully repurposed for new target groups. We aimed to investigate the effectiveness of IPS integrated with interdisciplinary treatment as usual (TAU) for patients with chronic pain in a tertiary pain center.

Methods
A randomized controlled trial comparing IPS integrated with TAU (n = 38) with TAU alone (n = 20) was conducted. Participants were patients with chronic pain who were 18–65 years of age and currently on long-term sick leave or disability benefits or unemployed. The primary outcome was employment within 12 months after enrollment, with additional long-term follow-up after 24 months. Secondary outcomes included health and quality of life, measured at baseline, 6 months, and 12 months.

Results
During 12-month follow-up, 52.8% in the IPS group and 38.9% in the TAU group had attained employment. The difference increased during 24-month follow-up but did not reach statistical significance. Findings on secondary outcomes were generally nonsignificant.

Conclusions
The IPS in Pain trial is the first study to evaluate the effect of IPS for patients with chronic pain conditions. It shows that IPS can be integrated into the daily practice of interdisciplinary pain treatment, with employment rates exceeding 50% in 1 year and a clear trend in favor of the IPS group. Results did not, however, reach significance. Larger randomized controlled trials are needed to draw clear conclusions about effectiveness.
History of solar neutrino observations
Authors: Nakahata Masayuki 
Published: February 2022

Abstract
The first solar neutrino experiment, led by Raymond Davis Jr, showed a deficit of neutrinos relative to the solar model prediction, referred to as the “solar neutrino problem” since the 1970s. The Kamiokande experiment, led by Masatoshi Koshiba, successfully observed solar neutrinos, as first reported in 1989. The observed flux of solar neutrinos was almost half the predicted value and confirmed the solar neutrino problem. This problem was not resolved for some time due to possible uncertainties in the solar model. In 2001, it was discovered that the solar neutrino problem is due to neutrino oscillations by comparing the Super-Kamiokande and Sudbury Neutrino Observatory results; this was the first model-independent comparison. Detailed studies of solar neutrino oscillations have since been performed, and the results of solar neutrino experiments are consistent with solar model predictions when the effects of neutrino oscillations are taken into account. In this article, the history of solar neutrino observations is reviewed with the contributions of Kamiokande and Super-Kamiokande detailed.
PREMATURE MENOPAUSE AND OBESITY DUE TO OOCYTE LOSS IN FEMALE MICE CHRONICALLY EXPOSED TO LOW DOSE-RATE γ-RAYS
Authors: Nakamura S , Tanaka III I B , Komura J , Tanaka S 
Published: February 2022

Abstract
In previous reports, the authors showed a significant overall increase in neoplasms originating from the ovaries (2007) and increased body weights (2007, 2010) in female B6C3F1 mice chronically exposed to low dose-rate γ-rays at 20 mGy/day (total doses = 8 (2007) or 6 Gy (2010)), as well as significant increases in serum leptin, total cholesterol, adipose tissue deposits and liver lipid content (2010). The present study chronicles the progression of ovarian failure in relation to obesity and dyslipidemia in female B6C3F1 mice chronically exposed to low dose-rate of γ-rays from 9 to 43 weeks of age (total dose = 4.8 Gy). We monitored changes in body weights, estrus cycles, ovarian follicle counts, serum cholesterol and serum leptin. The number of mice with irregular estrus cycles and increased body weights (with increased fat deposits) significantly increased from 30–36 weeks of age. Depletion of oocytes in ovaries from irradiated mice at 30 weeks of age (accumulated dose = 3 Gy) was also observed. Findings suggest that obesity in female B6C3F1 mice continuously irradiated with low dose-rate of γ-rays at 20 mGy/day is a consequence of premature menopause due to radiation-induced oocyte depletion.