bluuebunny/crossref_metadata_2025_split huggingface dataset:
Réseaux connectés d’enseignants et développement professionnel
Authors: Crinon Jacques , Ferone Georges 
Published: January 2022

Des réseaux connectés nés d’initiatives d’enseignants se sont considérablement développés dans les pays francophones ces dernières années. Ils revendiquent notamment une dimension de coformation par les pairs. À partir d’entretiens avec des enseignants de la fin de l’école primaire et du début du secondaire pratiquant soit la classe inversée (n =11) soit la « twictée » (n =19), nous cherchons à savoir en quoi, selon eux, la participation à un réseau d’innovateurs contribue à leur développement professionnel. L’étude décrit des types différents de participation au réseau. Elle indique en outre que les savoirs de référence ne semblent guère être au premier plan des échanges, plutôt centrés sur l’organisation pédagogique, les outils et les supports d’enseignement et la quasi-absence de controverses professionnelles. On constate ainsi l’incomplétude du processus de développement professionnel, si l’on s’en tient à la participation au réseau connecté, mais aussi la nécessité de considérer cette participation dans un ensemble plus large d’interactions et dans des trajets de développement et des réseaux personnels où la participation à un réseau peut pourtant jouer, à un moment donné, un rôle décisif.
Classe inversée en enseignement supérieur et dynamique d’élaboration du savoir : le point de vue des enseignants
Authors: Baillet Dorothée , Robin Françoise 
Published: January 2022

Suite au développement des technologies de l’information, l’enseignement supérieur évolue vers des dispositifs hybrides dont la classe inversée. Cet article rend compte d’une recherche qui tente de percevoir des repositionnements différenciés des espaces-temps et des acteurs en classe inversée. Nous avons interrogé neuf enseignants du supérieur en Belgique (partie francophone) qui se disent « inverseurs ». L'étude des raisons qui ont amené ces enseignants à opter pour le dispositif de la classe inversée permet de mettre en évidence l’importance des expériences personnelles ainsi que l’existence de différences relatives aux interactions avec les étudiants. Ces résultats couplés à l’analyse de la mise en place du dispositif à travers le triplet didactique (Sensevy, 2011) ont permis de mettre au jour deux idéal-types. Le premier est caractérisé par le contrôle de l’enseignant sur l’ensemble du dispositif ou par la dévolution de l’avancée du savoir aux étudiants. Le second alterne contrôle et dévolution.
A preferable modality for the differentiation of peripancreatic fluid collections: Endoscopic ultrasound
Authors: Xu Ning , Li Longsong , Zhao Danqi , Wang Zixin , Wang Xueting , Wang Runzi , Zeng Yanbo , Zhang Lei , Zhong Ning , Lv Ying , Linghu Enqiang , Chai Ningli 
Published: January 2022

Background and Objectives:
Peripancreatic fluid collections (PFCs), including walled-off necrosis (WON) and pancreatic pseudocysts (PPCs), are categorized by imaging modalities, including EUS, computed tomography (CT), and magnetic resonance imaging. Our study aimed to evaluate the effectiveness of EUS in differentiating PFCs compared with that of other modalities.

Subjects and Methods:
Data were collected retrospectively from 99 patients at fourteen centers who were recruited to undergo lumen-apposing metal stent placement to treat PFCs.

Results:
PFCs were detected by CT and EUS in 51 WON and 48 PPC patients. The accuracy in differentiating PFCs by EUS was much higher than that of CT (90.9% vs. 50.5%, P < 0.001). The accuracy in identifying WON on EUS was much higher than that on CT (82.4% vs. 13.7%, P < 0.001), while the accuracy in identifying PPC was comparable in these two modalities (89.6% vs. 100%, P > 0.05). WON patients required more times of debridement than PPC patients (P < 0.001).

Conclusion:
EUS can categorize symptomatic PFCs with higher accuracy than CT and is a preferred imaging modality to detect solid necrotic debris.
Long-term effects and benefits of Helicobacter pylori eradication on the gastric mucosa in older individuals
Authors: Chen Jie , Zhang Gansheng , Qin Jian , Huang Yiqin , Wang Yu , Li Zhongkuo , Ji Danian , Xiao Li , Yin Shuming , Bao Zhijun 
Published: January 2022

Background:
The current international consensus report indicated that all Helicobacter pylori (H. pylori)-positive patients should be treated. This study aimed to evaluate the long-term effects and benefits of H. pylori eradication on the gastric mucosa in the elderly population.

Methods:
We performed a retrospective cohort study with 311 individuals aged ≥60 years, including 83 with persistent H. pylori infection (persistent group), 128 with successful H. pylori eradication (eradicated group), and 100 without H. pylori infection (control group). The results of endoscopy and mucosal histology were investigated at baseline and followed up for 5 and 10 years.

Results:
In the 5 to 10-year follow-up, there was a significant difference in the atrophy score among the three groups (P < 0.001); however, no significant difference was observed in the intestinal metaplasia (IM) score (P > 0.05). There was no significant difference in the cumulative incidence of gastric neoplastic lesion (GNL) between the eradicated and persistent groups during the 5 to 10-year follow-up period (P > 0.05). The baseline IM score of patients with GNL was significantly higher than that of those without GNL in the eradicated and control groups (P < 0.05). In all patients with GNL, the mean interval time between baseline and diagnosis of GLN was more than 6 years. The severity of baseline mucosal IM (odds ratio: OR 3.092, 95% confidence interval [CI]: 1.690–5.655, P < 0.001) and H. pylori infection (OR: 2.413, 95%CI: 1.019–5.712, P = 0.045) significantly increased the risk for GNL.

Conclusions:
Older patients with a life expectancy of less than 5 to 10 years, especially those with moderate to severe gastric mucosal IM, may not benefit from the eradication of H. pylori to prevent gastric cancer.
Spectrum-effect relationship between serum HPLC fingerprints and activation of blood circulation and removal of blood stasis by Chuanxiong
Authors: Chen Ling , Deng Wei , Liu Shirong , Li Fengchao , Li Huimin , Jiang Guihua 
Published: January 2022

Purpose: To study the active ingredients of Chuanxiong (CX) in promoting blood circulation and removing blood stasis.
Methods: Blood-activating effects and serum HPLC fingerprints of CX extracts from different parts of China were studied and the spectrum-effect relationship between them was established by grey correlation analysis.
Results: After treatment with CX extracted using different solvents, hemorheology indices were lower than those in the model group, and the effect of dichloromethane was better than that of other solvents (p < 0.05 or p < 0.01). There were 6 common peaks by fingerprint analysis. Peaks 1 - 5 were identified as senkyunolide I, senkyunolide H, senkyunolide A, coniferyl ferulate and ligustilide, respectively.
Conclusion: Analysis of the spectrum–effect relationship indicates the contribution of the five components to the blood-activating effect of CX. The findings lend some scientific justification for using CX to remove blood stasis, and selection of quality evaluation indices for CX.
Mechanism of pharmacological effect of Angelica essential oil on anxiety based on network pharmacology and molecular docking
Authors: Liu Xiaoli , Zhang Xiaofei , Wang Fang , Xu Jie , Yang Ming 
Published: January 2022

Purpose: To investigate the pharmacological effect of Angelica essential oil (AEO) on anxiety disorder and the mechanism of action involved, using network pharmacology and molecular docking.
Method: Chemical compositions of AEO were determined using gas chromatography-mass spectrometry (GC-MS). The potential targets involved in the effect of AEO on anxiety were predicted by searching Bioinformatics databases. Cytoscape software was applied for networks construction. Analysis of Gene Ontology (GO) and pathway was done via R Programming Language, while molecular docking analysis was conducted by Autodock vina software.
Results: Network analysis showed that there were 10 bioactive components and 34 potential targets. The potential targets were distributed in cerebellar cortex, basic ganglia, hippocampal formation, amygdala, pons and medulla and liver. AEO was involved in multiple biological processes (BP), cell components (CC) and molecular functions (MF) associated with anxiety disorder. Molecular docking revealed good binding affinity between the major bioactive components and targets.
Conclusion: This study has revealed the pharmacological mechanism involved in the effect of AEO on anxiety, through network pharmacology and molecular docking. The pharmacological mechanism provides a firm theoretical basis for further studies in this area of research.
Cynaropicrin inhibits lung cancer proliferation by targeting EGFR/AKT signaling pathway
Authors: Li Wenjun , Xu Xuechao , Wan Yixin , Wang Hong , Tao Hongyan , Huang Huirong 
Published: January 2022

Purpose: To investigate the anti-proliferative effect of cynaropicrin on lung cancer cell lines, and the underlying molecular mechanism.
Methods: The effect of cynaropicrin treatment on the viabilities of H1975 and H460 cells was measured using Cell Counting Kit-8. Apoptosis was analysed by annexin-V/FITC staining, while protein expressions were assayed by western blotting.
Results: Treatment of H1975 and H460 cells with cynaropicrin at doses of 0.25 – 2.0 μM led to a marked reduction in their viability (p < 0.05). In cynaropicrin-treated H1975 and H460 cells, there was significant increase in apoptosis, when compared to control cells. Caspase-3 and caspase-9 levels were also significantly increased in H1975 and H460 cells on treatment with cynaropicrin at doses of 0.25 and 2.0 μM while treatment with cynaropicrin at doses of 0.25 - 2.0 μM significantly down-regulated the mRNA expression of CCND1 in the two cell lines (p < 0.05). Cynaropicrin markedly inhibited mRNA and protein expressions of EGFR, and also downregulated AKT in H1975 and H460 cells (p < 0.05). However, cynaropicrin significantly increased the expressions of miR-202 and miR-370.
Conclusion: Cynaropicrin exerts anti-proliferative and proapoptotic effects on H1975 and H460 lung cancer cells via deactivation of EGFR/AKT signaling pathway. Moreover, it upregulated the expressions of miR-202 and miR-370 in these cells. Thus, cynaropicrin has potentials for the treatment of lung cancer.
HCV RNA quantification in capillary dried blood spots with the Xpert® HCV Viral Load test for diagnosing chronic HCV infection, monitoring treatment and detecting reinfection
Authors: Bregenzer Andrea , Ottiger Cornelia , Krismer Cornelia , Sager Karin , Fux Christoph A. 
Published: January 2022

BACKGROUND: For patients with difficult venous access after long-term intravenous drug use, rapid point-of-care hepatitis C virus (HCV) RNA quantification in capillary whole blood with the Xpert® HCV Viral Load Fingerstick (VL FS) test (60 minutes) is a convenient and reliable method for diagnosing chronic HCV infection, monitoring treatment and detecting reinfection. However, an expensive GeneXpert® system must be available on site. In decentralised settings with a low case-load, dried blood spot (DBS) testing might be an alternative.
METHODS: Between December 2019 and January 2021, patients with an indication for HCV RNA quantification and informed consent provided 100 µl capillary whole blood each for on-site Xpert® HCV VL FS testing (reference) and DBS testing in the laboratory. For the latter, 100 µl blood, collected with an EDTA Minivette®, were transferred to a Whatman® 903 filter card. After drying for at least 1 hour, the DBS sample was packed into a sealable plastic bag with desiccant and sent to the central laboratory of our hospital, where it was stored at –20°C. For HCV RNA extraction, the whole DBS was cut out with an 18-mm puncher and transferred into 1.3 ml guanidinium thiocyanate-containing buffer (provided by Cepheid®). After mixing and incubating at room temperature for 2–3 hours, 1 ml supernatant was analysed with the Xpert® HCV VL test (105 minutes) (filter paper absorbs 0.3 ml).
RESULTS: Of 109 paired samples from 67 patients, 38 (34.9%) were positive with the Xpert® HCV VL FS test. Sensitivity and specificity of DBS testing were 89.5% (34/38; 95% confidence interval [CI] 75.9–95.8%) and 97.2% (69/71; 95% CI 90.3–99.2%), respectively. The six (5.5%) discordant results (four false negative, two false positive) all were observed in samples with HCV RNA detectable below the limit of quantification after 2–8 weeks of pan-genotypic direct-acting antiviral treatment or 5 weeks after acute hepatitis C in a patient clearing HCV spontaneously. Quantifiable results (n = 30; 16 genotype 1, 7 genotype 3, 4 genotype 4, 1 genotype 1a and 3a, 2 unknown; HCV RNA range: 2.74–6.66 log IU/ml) correlated well (R2 = 0.981). On average, uncorrected DBS test results were 1.30 ± 0.14 log IU/ml lower than Xpert® HCV VL FS test results (~42 μl instead of the expected 1000 μl plasma used). Storage of DBS samples at room temperature for 7 days before freezing reduced HCV RNA by 0.29 ± 0.12 log IU/ml.
CONCLUSION: HCV RNA can reliably be quantified with the Xpert® HCV VL test in capillary dried blood spot samples. Thus, access to capillary HCV RNA quantification for diagnosing chronic HCV infection, monitoring treatment and detecting reinfection can be extended to decentralised settings with a low case load.
PENGUATAN DAKWAH KEBANGSAAN IMAM MASJID RIJALI DI AMBON
Authors: Tuanany Ismail , Malawat Mahdi , Syarifudin Syarifudin 
Published: January 2022

Pengabdian ini mendeskripsikan rendahnya penghargaan masyarakat terhadap Imam masjid yang dilakukan pada masjid Imam Rijali IAIN Ambon. Metode pengabdian bentuk Community Based Research. Teknik Pengumpulan data menggunakan model FGD, dan Wawancara mendalam. Rumusan masalah terdiri dari dua aspek yakni; mendeskripsikan kondisi realitas tata kelola masjid Imam Rijali IAIN Ambon dan konsep pengkaderan imam masjid untuk mencegah penyuburan paham bermasalah di tengah masyarakat. Tujuan pengabdian ini untuk mendapatkan standarisasi model pengkaderan imam masjid sebagai solusi pencegahan paham radikalisme bermasalah yang ada di masjid. Kajian ini menemukan standarisasi pengkaderan dakwah kebangsaan pada Imam Masjid yang profesional dengan kualitas bacaan Al-Quran yang fasih sesuai dengan ilmu tajwid. Teknik analisis data menggunakan teori konstruksi sosial untuk menganalisis fakta sosial realitas rendahnya penghargaan profesi Imam masjid sebagai tokoh edukasi rohani kebangsaan pada masjid Imam Rijali IAIN Ambon. Kajian ini menunjukkan bahwa ada tiga aspek temuan antara lain; 1) Diduga kuat peran kolonial Belanda ikut campur terhadap tata kelola masjid yang terjadi pada tahun 1943 yang mengakibatkan dua tradisi pemahaman yakni pemahaman Imam masjid tak perlu digaji dan imam perlu dihargai sebagai tokoh spiritual di masjid desa adat dan masjid kota; 2) Adanya konstruksi sosial yang terbentuk di tengah masyarakat terkait profesi imam yang sudah disepakati sebagai tradisi; 3) Peran masjid sebagai pusat edukasi rohani kebangsaan belum aktif secara baik. Perlu adanya akademi pengkaderan Imam di masjid sebagai pencetak sumber daya rohani dakwah kebangsaan di masjid sebagai solusi penyiapan kader dakwah kebangsaan. Bila pengkaderan imam masjid dibentuk secara profesional maka peran imam masjid sebagai bintang utama penguatan rohani kebangsaan mampu mencegah paham bermasalah di tengah masyarakat. Kajian ini memberikan dampak positif pada masjid untuk menemukan model pengkaderan imam masjid yang memiliki wawasan dakwah kebangsaan untuk menjaga stabilitas sosial persatuan dan persaudaraan di tengah masyarakat majemuk.
A literature review of eutrophication in Life Cycle Assessment. Relevance for pampean agroecosystems in Argentina
Authors: Conci Eliana , Becker Analía Rosa , Arena Alejandro Pablo , Civit Bárbara María 
Published: January 2022

The tools that operate within the framework of life cycle thinking have acquired great relevance, since they make it possible to determine the environmental profile of the system being evaluated. One of the risks deriving from the various economic activities is the eutrophication of water bodies and soil, and these categories are considered in all Life Cycle Impact Assessment (LCIA) models. However, aquatic and terrestrial eutrophication is not yet exhaustively explored in the field of Life Cycle Assessment (LCA) in Argentina.
A systematic analysis of specific national and international antecedents on these impact categories is carried out, focusing on terrestrial ecosystems, given the productive matrix and the advance of the agricultural frontier in the region. In the absence of research articles, it is deduced that there are no site-dependent characterizing factors (CFs) to evaluate environmental impacts in environmentally significant areas, given that there are no antecedents on the integrated analysis of aquatic and terrestrial ecosystems. The methods and their models will be selected based on the one that best suits regional conditions, following the guidelines agreed upon at the Pellston Workshop 2018. This research can be further developed, continuing with the characterization of the ecosystems receiving the emissions. Argentina is currently considered one of the major agricultural regions of the world, with most activity centered in the Pampa region. The development of regional indicators for this region within the LCIA stage is of great relevance, since it will allow the quantification of environmental impacts derived from activities of great economic importance for the country, positioning itself as an advance in the study of environmental risks in the region.
ANALYSIS OF EXPERIENTIAL AND EMOTIONAL MARKETING EFFECTS ON THE DECISION TO ENTER IN UNIVERSTAS AMIKOM YOGYAKARTA
Authors: Amrullah Yusuf Amri 
Published: January 2022

This study analyzes the influence of Experiential Marketing and Emotional Marketing on The Decision to Enter at Universitas AMIKOM Yogyakarta. The purpose of this study was to examine the effect of using Experiential Marketing and Emotional Marketing on The Decision to Enter at Universitas AMIKOM Yogyakarta. This research is vital to be used by companies or agencies that will conduct marketing. Respondents in this study were new students of Universitas AMIKOM Yogyakarta force 2018/2019 with at least one faculty represented by 1 study program, the questionnaire to distributed amounted to 200 questionnaires. Data analysis in this research uses validity test, reliability test and classic assumption test. The results of data processing using SPSS, the results shown are Experiential Marketing and Emotional Marketing influence on The Decision Enter.
Ekonomi Syariah : Bergerak Menuju Kapitalisme Religius ?
Authors: Prasetyo Heri , Hermansyah Hermansyah 
Published: January 2022

The economic system is a fundamental element that determines the economic performance of a country. Various forms of economic systems that have ever existed, including large economic systems such as capitalism, socialism adopted by various countries have become a guide and foundation for the country's economic policies. Then the emergence of a complementary thought discourse on an economic system based on religious values with theological arguments that Islam is a divine religion based on revelation (the Qur'an) functions to guide human life both socially, politically, and economically. the scarcity of literature that explains the values of philosophy, institutions, principles, norms, and values of Islamic economic law.
The author uses a literature study method or literature study by examining the literacy of opinions, ideas from thinkers and experts on classical, contemporary, and sharia modern economic systems such as Adam Smith, Lester Thurow, Max Weber, Adi Warman Karim, Fazlurrahman, Umar Chapra, Syed Nawab Haider Naqvi, Ibn Khaldun, Ibn Taymiyah Mubyarto. Furthermore, notes on the normativism of the Islamic economic system are important because they are related to the desired religious capitalism. Then, some of the arguments for religious capitalism are presented by looking at philosophical factors, historical-aspirational factors, and also factors that can be called futuristic.
In the philosophical study, the author concludes that Islamic economic religious capitalism is a form of the dialectical process of the earth system and the sky system. Harmonization of rationalism and spiritualism. The futuristic discussion shows that Islamic economic religious capitalism can be the end of history. But that does not necessarily stop the social challenges that arise. Capitalism itself is still undergoing changes, and shocks. The religious capitalism of Islamic economics is to see how Islamic economics will undergo a metamorphosis for the people of Indonesia, although there is no harm in advancing it as a futuristic study, as a future global economic system because it is claimed to carry universal values.
Assessment of Fetal and Infant health status based on Non-Stress Test
Authors: Rezaee Moradali Monireh , Zareipour Moradali , Rezaei Zhila Mohammad 
Published: January 2022

Introduction: Non stress test (NST) is commonly considered as a screening test to assess the health of the fetus especially in high risk pregnancies in most studies. The purpose of this study was to Assessment of fetal and Infant health status based on Non-Stress Test. Methods: This study was a case-control design carried out on 984 pregnant in Urmia selected by census sampling during 2014-2015; 500 pregnant had experienced NST and considered as case group and 484 pregnant had not experienced NST and considered as control group. Data were collected using records of NST among mothers and checklist including variables related to maternal characteristics such as fetal characteristics. The data were analyzed through SPSS version 22 software. Results: In pregnant women who experienced NST, the mean age, Apgar min 1 and 5 was significantly different and NST group had better situation than other group (p=0.001). Fetal distress was more in the presence of meconium (p=0.0001). In binary logistic regression analysis, meconium and NST were presented as a risk factor in the model, that is, by shifting one level of the meconium or NST status (yes/no) (OR Meconium = 14.262, p = 0.0001; OR NST = 2.874, p = 0.001). Conclusion: Using non stress test to observe the abnormal results of the fetus especially meconium-stained amniotic fluid is crucial and vital because can prevent the fetal distress, infection of pregnant women and fetus and even the mortality of the fetus.
Jornalismo e redes sociais
Authors: Costa Ruthy Manuella de Brito , Carvalho Cristiane Portela de 
Published: January 2022

O desenvolvimento da Internet trouxe e continua trazendo significativas mudanças para o jornalismo e suas práticas. Um dos maiores impactos é a perda de domínio da informação por parte dos veículos tradicionais de comunicação. Nesse sentido, o presente trabalho tem como objetivo fazer um levantamento sistematizado acerca das novas práticas e reconfigurações no campo jornalístico a partir da internet e por conseguinte com o surgimento das redes sociais virtuais. Para tanto, metodologicamente se sustenta em revisão de literatura, tendo como principais aportes teóricos Castells (2015, 2017), Recuero (2009) e Jenkins (2009). A leitura e sistematização das informações acerca dessa temática permitem perceber que o meio é influenciado pelo conteúdo que nele existe e pelas interações em torno desse conteúdo, assim, as redes sociais na internet não surgiram para suplantar o jornalismo, pelo contrário, elas surgem como novas ferramentas e novos espaços de interação social para o jornalismo.