bluuebunny/crossref_metadata_2025_split huggingface dataset:
Age-related readjustments of caucasian men’s functional reserves in the North
Authors: Аверьянова И.В. , Луговая Е.А. 
Published: January 2022

Цель работы - определение доли лиц, характеризующихся отклонениями физиологических параметров от нормативных диапазонов, и формирование паттернов функциональных резервов у подростков, юношей, мужчин среднего возраста и лиц пожилого возраста. Впервые проведена оценка динамики функциональных резервов на основе отклонений от нормативных референсов некоторых показателей физического развития, сердечно-сосудистой системы, биохимического и микроэлементного профиля, а также характеристик основного обмена и дыхания в онтогенетическом аспекте на основе построения паттернов степени напряжения анализируемых систем у лиц мужского пола, постоянно проживающих на Севере. Дан прогноз возрастного изменения изученных морфофизиологических параметров у лиц пожилого возраста. Результаты исследования показали, что паттерны отклонения анализируемых параметров свидетельствуют о нарастании напряжения функций систем в возрастном аспекте. Это проявляется в кумуляции отклонений в виде возрастных изменений показателей физического развития (увеличение ИМТ), сердечно-сосудистой системы (увеличение доли лиц с высоким нормальным АД и артериальной гипертензией по САД и ДАД), нарастания степени нарушений углеводного обмена (увеличение индекса инсулинорезистентности и гипергликемии натощак), возрастания степени дислипидемии относительно липидного обмена, трансформации нарушений микроэлементного профиля (усилении степени дефицита и возрастного избытка химических элементов). Это наблюдали на фоне снижения основного обмена веществ и показателей функции внешнего дыхания у современных жителей-северян старшего возраста.
This study determined proportion of males whose physiological parameters were out of standard ranges and made patterns of their functional reserves to see dynamics in the row of teenagers, young adults, middle-aged adults, older adults. For the first time, dynamics of functional reserves was evaluated based on deviations from standard values existing for physical development, cardiovascular system, biochemical and trace element pictures, as well as characteristics of basic metabolism and breathing in ontogenetic aspect. The evaluation was performed by creating patterns of tension in subjective body systems under the North extremes to make predictive age-related changes older adults morphophysiological indicators. The results the patterns exhibited increasingly dysregulated functioning in the age aspect. That could be seen in age-related stress observed in physical development variables (accelerated body mass index), cardiovascular system (higher proportion of people with high normal blood pressure and arterial hypertension in systolic and diastolic blood pressure), carbohydrate metabolism disorders (higher index of insulin resistance and fasting hyperglycemia), more pronounced dyslipidemia, microelement disorders such as more severe age-related deficiency or excess. Those deviations existed together with worsening in basic metabolism and external respiration function in modern northerners of working age.
Morphological signs of neurogenic inflammation in the heart of rats during aging
Authors: Чумасов Е.И. , Петрова Е.С. , Коржевский Д.Э. 
Published: January 2022

С помощью гистологических методов окраски толуидиновым синим, гематоксилином и эозином и иммуногистохимических реакций на белок PGP 9.5, тирозингидроксилазу (ТГ), белок Iba-1, изучены клеточные изменения в разных отделах сердца крыс линии Wistar в возрасте 18- 23 мес. В соединительной ткани основания сердца обнаружены очаговые воспалительные инфильтраты, внутри которых выявлены PGP 9.5 и ТГ сплетения, состоящие из парасимпатических и симпатических нервных волокон. В области клапанного аппарата, на границе фиброзного кольца и миокарда правого предсердия, обнаружены патологические изменения нервных структур - дегенерация нервных пучков и зернистый распад варикозных аксонов терминального сплетения. Установлены тесные взаимоотношения аксонов терминальной нервной сети с клетками воспалительных инфильтратов и кровеносными сосудами. Определены закономерности встречаемости в различных отделах миокарда у старых животных нейроклеточных воспалительных комплексов, состоящих из нервных волокон, кровеносных капилляров и клеток-участников местного воспалительного процесса (тучных клеток, макрофагов, фибробластов, плазмоцитов). Установлен хронический характер нейрогенного воспаления в сердце при старении.
Using histological methods of staining with toluidine blue, hematoxylin-eosin and immunohistochemical reactions for the PGP 9,5 protein, tyrosine hydroxylase (TH), Iba-1 protein, cellular changes in different parts of the heart of Wistar rats at the age of 18-23 months were studied. In the connective tissue of the heart base, focal inflammatory infiltrates were found, near which PGP 9.5 and TH plexuses, consisting of parasympathetic and sympathetic nerve fibers, were detected. In the area of the valvular heart apparatus, at the border of the anneau fibreux and the myocardium of the right atrium, pathological changes in nerve structures were found: degeneration of nerve fibers and granular destruction varicose axons of the terminal plexus. A close relationship has been established between axons of the terminal nervous network and cells of inflammatory infiltrates and blood capillaries. The features of the localization of neurocellular inflammatory complexes consisting of nerve fibers, blood capillaries and cells participating in the local inflammatory process (mast cells, histiocytes, monocytes, fibroblasts, plasma cells) in various parts of the myocardium in old animals are described. The chronic nature of neurogenic inflammation in the heart during aging has been established.
Morphological differences of the fallopian tube ampoule in young and old age
Authors: Баландина И.А. , Некрасова А.М. , Баландин А.А. 
Published: January 2022

Работа основана на морфологическом исследовании ампул маточных труб 130 рожавших женщин молодого и старческого возраста. Применены макрометрический, гистологический, иммуногистохимический и микрометрический методы исследования. Выявлены закономерности возрастной морфологической изменчивости ампулы маточной трубы, проявляющиеся в уменьшении параметров их длины, а также наружных диаметров в середине ампулы и в местах перехода перешейка в ампулу и ампулы в воронку от молодого возраста к старческому возрасту. Гистоархитектоника ампул маточных труб у женщин в старческом возрасте характеризуется уплощением эпителия слизистой оболочки, образующей обилие близлежащих утолщенных складок, формирующих неравномерное сужение просвета ампулы. Определяется истончение мышечной оболочки с разрастанием вместо нее соединительной ткани и скоплением адипоцитов в подсерозной основе. В старческом возрасте отмечается более выраженная экспрессия виментина, прослеживающаяся не только в эндотелии и субэндотелиальном слое кровеносных сосудов, включая капилляры, но и в отдельных фибробластах. Установлено, что особенности микрометрических характеристик ампул маточных труб заключаются в уменьшении внутреннего периметра эпителиальной выстилки и площади просвета, наряду с увеличением площади их стенки при срединном сечении, в старческом возрасте в сравнении с молодым.
The work is based on a morphological study of ampoules of the fallopian tubes of 130 young and senile women who gave birth. Macrometric, histological, immunohistochemical and micrometric methods of investigation were applied. The regularities of age-related morphological variability of the fallopian tube ampoule are revealed, which are manifested in a decrease in the parameters of their length, as well as external diameters in the middle of the ampoule and at the places of transition of the isthmus into the ampoule and ampoule into the funnel from young age to old age. Histoarchitectonics of ampoules of the fallopian tubes in women in old age is characterized by flattening of the epithelium of the mucous membrane, which forms an abundance of nearby thickened folds that form an uneven narrowing of the lumen of the ampoule. The thinning of the muscle membrane is determined with the growth of connective tissue instead of it and the accumulation of adipocytes in the subserose base. In old age, there is a more pronounced expression of vimentin, which can be traced not only in the endothelium and subendothelial layer of blood vessels, including capillaries, but also in individual fibroblasts. It was found that the features of the micrometric characteristics of the fallopian tube ampoules consist in a decrease in the inner perimeter of the epithelial lining and the lumen area, along with an increase in the area of their wall at the median cross-section in old age compared with young age.
Transcheter aortic valve implantation as a method of treatment of chronic heart failure in elderly and old patients: Literature review (part 1)
Authors: Козлов К. Л. , Богомолов А.Н. , Сенькина Е.И. , Лукьянов Н.Г. , Башкатова Л.В. , Шишкевич А.Н. 
Published: January 2022

Стеноз аортального клапана (АК) - самое частое приобретенное клапанное заболевание с растущей распространенностью из-за старения населения, требующее хирургического или эндоваскулярного вмешательства. Транскатетерная имплантация АК (Transcatheter Aortic Valve Implantation, TAVI) представляет собой настоящую революцию в области интервенционной кардиологии для лечения пациентов старческого возраста или из группы высокого риска с тяжелым симптомным стенозом АК. TAVI позволяет выполнять коррекцию аортального порока наиболее тяжелой группе больных ХСН с выраженной коморбидностью, которым противопоказано выполнение открытой операции по замене АК, для прерывания порочного круга в прогрессировании ХСН, стимуляции обратного ремоделирования миокарда, облегчения симптомов, улучшения качества жизни и прогноза больных, а также в качестве «моста» к трансплантации сердца. Благодаря разработке устройств нового поколения, TAVI превратилась из сложной и опасной процедуры в эффективную и безопасную методику. Наибольший научный интерес в настоящее время представляет изучение долговечности клапана и возможности расширения показаний к выполнению TAVI у категорий пациентов с низким хирургическим риском, а также более молодого возраста.
Aortic valve (AV) stenosis is the most common acquired valvular disease with an increasing prevalence due to an aging population, requiring surgical or endovascular intervention. Transcatheter Aortic Valve Implantation (TAVI) represents a real revolution in the field of interventional cardiology for the treatment of elderly or high-risk patients with severe symptomatic AV stenosis. TAVI allows for the correction of aortic defect in the most severe group of patients with chronic heart failure (CHF) with severe comorbidity, who are contraindicated for open surgery to replace AV, in order to interrupt the vicious circle in the progression of CHF, stimulate reverse myocardial remodeling, alleviate symptoms, improve the quality of life, and prognosis of patients, and also as a «bridge» to heart transplantation. With the development of next-generation devices, TAVI has evolved from a complex and dangerous procedure to an effective and safe technique. Currently, the greatest scientific interest is the study of valve durability and the possibility of expanding the indications for performing TAVI in categories of patients with low surgical risk, as well as in younger age groups.
Effects of socio-economic factors on old-age mortality in Russia
Authors: Сафарова Г. Л. , Кипяткова В.А. , Сафарова А. А. 
Published: January 2022

Исследование смертности занимает важное место в демографии в целом и в особенности в демографии старения. России свойственна неоднородность демографического развития, в частности региональная дифференциация показателей смертности населения. Работа посвящена анализу зависимости смертности в регионах России в старших возрастных группах от социально-экономических показателей. Исследование проводили с использованием методов регрессионного анализа, где в качестве единиц наблюдения выступали субъекты РФ, в качестве объясняемой переменной - смертность мужского (женского) населения старшего (60+) возраста, представленная в виде стандартизованных по структуре населения коэффициентов. В результате работы выявлены значимые социально-экономические факторы, позволяющие объяснить различия уровней смертности в субъектах РФ.
Studies of old-age mortality are an important part of demography, especially the demography of ageing. Demographic development of Russia is characterized by heterogeneity including regional differences in mortality. The aim of the paper is to analyze the dependence of mortality at old-age groups on socio-economic indicators. The study is conducted using methods of regression analysis; the units of observation are the regions of the Russian Federation, the explained variable is the mortality rate of male (female) population at older (60+) ages standardized by the population-age structure. As a result, the significant socio-economic factors, explaining the differences of mortality rates in the regions of the Russian Federation, were identified.
EVALUASI SURVEILANS COVID-19 DI PUSKESMAS BULELENG I KABUPATEN BULELENG
Authors: Wardani Ni Luh Putu Seri , Purnawan I Nyoman , Nyandra Made 
Published: January 2022

This research has the aim to evaluate aspects of COVID-19 surveillance input in Buleleng Health Center I. The research design used is descriptive research with qualitative approach. Data collection techniques used are in-depth interview techniques with research informants as many as 5 people with purposive sampling techniques and data retrieval techniques using structured interviews, documentation studies and observations. The conclusion of this study is that man is not in accordance with the guidelines; methode in accordance with the guidelines is the availability of guidelines for prevention and prevention of COVID-19 Disease Rev.5; the allocation of funds has not been in accordance with the guidelines because the amount of funds available does not match the increase in cases that occur but the source of funds is appropriate; facilities and infrastructure are only problems of the internet network that have not been in accordance with the guidelines
The last day in life of the Soviet Union. The first day of the existence of the Russian Federation
Authors: Девятов С.В. 
Published: January 2022

Статья посвящена истории одного дня в Московском Кремле. Это был последний день существования СССР – 25 декабря 1991 года. На фоне показа исторических событий того времени рассказывается о смене Государственного флага СССР на Государственный флаг Российской Федерации. Впервые публикуется уникальный документ – акт о замене флага, написанный непосредственно после этого события и подписанный всеми участниками.
The article is devoted to the history of one day in the Moscow Kremlin. It was the last day of the USSR's existence – December 25, 1991. The events of that time create a perfect background, the Soviet flag was lowered from Kremlin and then replaced by the three-color Russian Federation flag. For the first time published is a unique document — the Act of flag replacement written shortly after the events and signed by all participants.
Size effect at testing strength properties of concrete
Authors: Akram Amanda 
Published: January 2022

Various strength characteristics of concrete are considered as fracture parameters. The compressive strength of concrete is of paramount importance when designing concrete structures, whereas tensile strength of concrete is the basic property when estimating cracking resistance of a structure and analysing fracture processes in concrete. When testing the compressive strength of concrete, the results are dependent on the shape and dimensions of used specimens. Some findings reported in the literature suggest that size effect exists also when testing such fracture properties of concrete as tensile strength. Unfortunately this problem is much less recognized and described compared to size effect in compressive test results. In this paper, the experimental investigation is presented on how the length of cylindrical specimens influences the tensile splitting strength of concrete obtained by means of the Brazilian method. Additional variable parameters were: type of aggregate (natural gravel and crushed granite) and cement-water ratio (C/W = 1.8 and C/W = 2.6). In conducted laboratory experiments a higher splitting tensile strength of concrete was noted for all specimens with nominal dimensions of 150×150 mm, compared to specimens 150×300 mm in size, regardless of type of aggregate or cement-water ratio.
Primary Education Teacher Training: an exploratory study from the lockdown towards the post Covid period
Authors: Di Barbora Eugenia , Bragatto Lucia , Locuoco Lucia , Paci Daniela , Tavano Maura 
Published: January 2022

This exploratory study, conducted during the first Covid-19 lockdown, formed part of the practical module of the Teacher Training in Primary Education course at the University of Udine, and was carried out on a sample of trainees enrolled on the course. The research had the following objectives: to understand the effects of the Covid-19 lockdown on trainees and to reflect on the impact on planning of teaching in a traditional classroom environment or in VLE, Virtual Learning Environment. In order to improve the practical components of the course, observations focused on organizational, methodological and pedagogical aspects. The data, gathered in an online questionnaire, provided a comparison of teacher training delivered in person in the pre-Covid period and in later training online. The data also provided information on the strengths and weaknesses of classroom and distance learning, on the use of technology and on the professional development of teachers in the future. The study found a multitude of issues that will need to be further explored in the post Covid period, including rethinking models and approaches in initial teacher training.

Tirocinio di Scienze della Formazione Primaria: uno studio esplorativo nel primo lockdown per Covid.

Il presente studio esplorativo è stato promosso, durante il primo lockdown per Covid-19, all’interno del Tirocinio del Corso di Studi in Scienze della Formazione Primaria dell’Università di Udine su un campione di studenti iscritti al tirocinio. La ricerca esplorativa ha avuto come obiettivi: comprendere le ricadute nei tirocinanti conseguenti allo stato di emergenza e riflettere sulla didattica in presenza e a distanza sui piani organizzativo, metodologico e pedagogico per potenziare l’offerta formativa del tirocinio. I dati, desunti da un questionario online, hanno permesso un confronto sul tirocinio in presenza nel periodo pre-Covid e successivamente svolto in DaD. I dati hanno fornito anche risultati su punti di forza e criticità della didattica in presenza e a distanza, sull’uso delle tecnologie e sulla professionalità docente futura. Lo studio ha inoltre rilevato una molteplicità di aspetti che andranno ulteriormente approfonditi per il periodo post Covid-19, tra cui il ripensamento di modelli ed approcci nella formazione iniziale degli insegnanti.
The sanitary emergency and language teachers’ training needs in Italy
Authors: Nitti Paolo 
Published: January 2022

Language teaching represents one of the language sciences that can be regarded as applicative. The teaching of modern languages is a discipline that is intrinsically interconnected with other disciplines and, from the moment it was scientifically recognized on the epistemological level, it has been characterized by a keen interest and affinity towards the technologies. This essay showcases the results of a survey conducted on a sample of teachers on the effects of the pandemic on language teaching in Italy.

L’emergenza sanitaria e i bisogni formativi dei docenti di lingua in Italia.

La didattica delle lingue rappresenta una delle scienze del linguaggio di carattere applicativo. La glottodidattica inoltre è una disciplina interconnessa intimamente con altri campi del sapere e, fin dai primi momenti di autonomia sul piano dello statuto epistemologico, con la tecnologia. Questo contributo permette di analizzare i risultati di un’indagine condotta su un campione rappresentativo di insegnanti in merito agli effetti della pandemia sull’insegnamento delle lingue in Italia.

L’emergenza sanitaria e i bisogni formativi dei docenti di lingua in Italia
La didattica delle lingue rappresenta una delle scienze del linguaggio di carattere applicativo. La glottodidattica inoltre è una disciplina interconnessa intimamente con altri campi del sapere e, fin dai primi momenti di autonomia sul piano dello statuto epistemologico, con la tecnologia. Questo contributo permette di analizzare i risultati di un’indagine condotta su un campione rappresentativo di insegnanti in merito agli effetti della pandemia sull’insegnamento delle lingue in Italia.
Higher apprenticeship as educational strategy after the pandemic
Authors: Bertuletti Paolo , Potestio Andrea 
Published: January 2022

This article analyzes strengths and weaknesses of the higher apprenticeship programme carried out by the University of Bergamo within the bachelor’s degree in educational sciences since the academic year 2017/2018. Starting from the voices of apprentices and tutors, a qualitative research tries to find out whether higher apprenticeship may be a good teaching strategy to enhance the principle of alternation between theory and practice in tertiary education.

L’apprendistato di terzo livello come strategia formativa per le società dopo il Covid.

L’articolo esplora punti di forza e criticità dei percorsi di apprendistato di terzo livello avviati dall’Università di Bergamo a partire dall’a.a. 2017/2018 nell’ambito del corso di laurea triennale in Scienze dell’educazione. La ricerca qualitativa consente, grazie alle testimonianze di apprendisti e tutor, di descrivere situazioni ed episodi di apprendimento e di mettere in evidenza come l’apprendistato di terzo livello, almeno potenzialmente, possa costituire un’ottima strategia didattica per realizzare il principio dell’alternanza formativa negli studi terziari.