bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of Deviations of Implants Installed with Prototyped Surgical Guide and Conventional Guide: In Vitro Study
Authors: Rodrigues João Marcelo Meireles , Santos Pâmela Leticia , Mendonça Gustavo , Faloni Ana Paula de Souza , Finoti Livia Sertori , Margonar Rogério 
Published: September 2022

Abstract
Objective The study aimed to assess the angular and linear deviations of implants installed in mannequins aided by surgical guides produced with the techniques of dual tomography (DT), model-based tomography (MT), and nonprototyped guide.
Materials and Methods Implants were installed in mannequins of a partially edentulous maxilla and divided into three groups: Group C (n = 20), implants installed using the conventional technique with flap opening and conventional guide; Group DT (n = 20), implants installed using guided surgery with the dual tomography technique; and Group MT (n = 20), implants installed using the model-based tomography technique. After implant installation, the mannequin was subjected to a computed tomography (CT) to measure the linear and angular deviations of implant positioning relative to the initial planning on both sides.
Results There was a higher mean angular deviation in group C (4.61 ± 1.21, p ≤ 0.001) than in groups DT (2.13 ± 0.62) and MT (1.87 ± 0.94), which were statistically similar between each other. Similarly, the linear deviations showed group C with the greatest discrepancy in relation to the other groups in the crown (2.17 ± 0.82, p = 0.007), central (2.2 ± 0.77, p = 0.004), and apical (2.34 ± 0.8, p = 0.001) regions.
Conclusion The techniques of DT and MT presented smaller angular and linear deviations than the conventional technique with the nonprototyped guide. There was no difference between the two-guided surgery techniques.
New Technique Seeking Prophylaxis in the Displacement of Distal Ventriculoperitoneal Shunt Catheter – Case Report
Authors: Melo João Victor Oliveira de , Silva Rebeca Brasil da , Reis Franklin , Amorim Robson Luís Oliveira de 
Published: September 2022

AbstractIdiopathic intracranial hypertension is a comorbidity treated in neurosurgical practice today with the ventriculoperitoneal derivation technique. However, despite its great safety and efficacy, this technique is susceptible to infrequent failures, such as displacement of the catheter leading to the need for reoperation. In the present article, we report a case involving a peritoneal catheter tip retropulsion for subcutaneous tissue in an obese patient with posterior correction using an extending connector to the distal catheter, without harming the drainage flow. In our case report, the patient went on without complications and without the occurrence of new displacement after 8 months of surgery. The results obtained by this technique supported the idea that this alternative construction minimizes the risk of displacement of the peritoneal tip catheter in obese patients and with high intra-abdominal pressure, helping to reduce the need for reoperations. In addition, the present case report supports the need for further studies and clinical trials on the subject.
Endoscopic Third Ventriculostomy in the Pediatric Population: Case Series Report
Authors: Pinto Hortência Angelina Silva , Ferreira Ana Luísa de Cássia Magalhães , Deus Isadora Barbosa de , Ferreira Darlan Rebolças Gama , Gonçalves Laryssa Vieira , Faleiro Rodrigo Moreira 
Published: September 2022

Abstract
Objective Hydrocephalus is characterized by multi- or uniloculated ventricular dilatation, and there are differences between the etiology and therapeutic response of each type. Endoscopic third ventriculostomy (ETV) is indicated for the treatment of obstructive hydrocephalus, with a reported efficacy between 50% and 76%. Reduced efficacy of the procedure has been demonstrated in communicating hydrocephalus due to multifactorial pathogenesis, and, in patients with myelomeningocele, its efficacy ranges from 15% to 20% at birth. The present study aims to compare the efficacy of ETV in the treatment of congenital obstructive hydrocephalus (COH) and acquired obstructive hydrocephalus (AOH) in the pediatric population.
Methods A retrospective study of 169 endoscopic surgeries performed by the senior author in two institutions, one public (Hospital João XXIII, Belo Horizonte, Minas Gerais) and another private (Hospital Felício Rocho, Belo Horizonte, Minas Gerais), in the period from 2003 a 2020. From the selection of 169 patients, only 77 cases fit the age profile ≤12 years of the present study. Of these, 46 were male, and the age range ranged from 10 days to 12 years. The study included multiple etiologies, which were divided into 2 groups, 34 related to COH, and 43 to AOH.
Results Regarding the cases of COH, 22 were submitted to ETV as the main treatment, with 14 (63.63%) effective and 8 (36.36%) ineffective procedures. As for the cases of AOH, 13 patients underwent ETV, and 8 (61.53%) procedures were effective, and 5 (38.46%), ineffective.
Conclusions Through the calculation of the p-value of 0.49, we concluded that it cannot stated that the efficacy of ETV is greater in COH than in AOH.
Characterization, Physical Properties, and Biocompatibility of Novel Tricalcium Silicate–Chitosan Endodontic Sealer
Authors: Maharti Ike D. , Suprastiwi Endang , Agusnar Harry , Herdianto Nendar , Margono Anggraini 
Published: September 2022

Abstract
Objective The purpose of this study was to compare the characteristics, physical properties, and biocompatibility of the novel tricalcium silicate–chitosan (TCS-C) sealer with AH Plus and Sure-Seal Root.
Materials and Methods The TCS-C powder was prepared by mixing tricalcium silicate with 2% water-soluble chitosan at a 5:1 ratio, followed by sufficient addition of 10 g/mL ratio of double-distilled water to form a homogeneous cement. Material characterizations (the Fourier Transform InfraRed [FTIR] and X-ray diffraction [XRD]), physical property investigations (flow and film thickness), and cytotoxicity tests in 3T3 mouse embryo fibroblast cell (MTT assay method) were performed on sealers, and the results were compared with those of the commercial products.
Statistical Analysis Statistical analysis was performed on flow and film thickness. The normality of the data was tested using the Shapiro–Wilk test. Statistical analysis was performed with one-way analysis of variance (ANOVA). The level of significance was set at p < 0.05.
Results The TCS-C showed a mean flow of 31.98 ± 0.68 mm, compared with Sure Seal Root at 26.38 ± 0.69 mm and AH Plus at 26.50 ± 0.12 mm. The TCS-C showed a mean film thickness of 60 ± 10.0 mm compared with Sure-Seal Root at 50 ± 10.0 mm and AH Plus at 40 ± 15.8 mm. The TCS-C exhibited low to no cytotoxicity in fibroblast cell at all concentrations and exposure times.
Conclusion Adding water-soluble chitosan may improve the physical and biologic properties of tricalcium silicate cement. The novel TCS-C sealer did not fully meet the physical properties of an endodontic sealer, but it was not cytotoxic to fibroblast cells.
Atypical Presentation of Marginal Zone Lymphoma as Isolated Diffuse Bone Marrow Involvement: Utility of F-18 FDG PET/CT in Diagnosis and Response Assessment
Authors: Gauthaman Dinesh Kumar , Subramanyam Padma , Palaniswamy Shanmuga Sundaram 
Published: September 2022

AbstractNon-Hodgkin's lymphoma (NHL) with secondary bone marrow involvement is relatively common. However, isolated involvement of bone marrow in marginal zone type of NHL is atypical and rare. Here, we describe a patient of atypical marginal zone lymphoma with isolated bone marrow involvement who presented with weight loss and bicytopenia, where F-18 FDG PET/CT (fluorine-18-labeled fluorodeoxyglucose positron emission tomography with computed tomography) imaging played a pivotal role in establishing the diagnosis when conventional imaging modalities were unremarkable. The patient was successfully treated with systemic chemotherapy (rituximab, cyclophosphamide, prednisolone) and achieved complete remission, as demonstrated by a follow-up F-18 FDG PET/CT scan.
Preradioactive Iodine Thyroglobulin Levels as Predictors of Metastasis in Well-Differentiated Thyroid Carcinoma Patients
Authors: Darmawan Budi , Sari Meutia , Susilo Stefani , Kartamihardja Achmad Hussein S. 
Published: September 2022

Abstract
Objective The aim of this study was to determine the cut-off value of thyroglobulin (Tg) levels as a predictor of metastases in post total thyroidectomy patients with well-differentiated thyroid carcinoma (DTC).
Materials and Methods A retrospective case-control study with an observational diagnostic approach was done. Subjects were 102 DTC patients divided into a case group with metastases and a control group without metastases. Tg and antithyroglobulin antibody (ATA) levels on thyroid-stimulating hormone (TSH)-stimulated preradioactive iodine were compared with each other. Diagnosis of metastases was based on postradioactive iodine whole-body scan. The cut-off value for Tg preradioactive iodine and the area under the curve (AUC) were obtained from the receiver operating characteristic curve.
Result The characteristics and histopathological type of DTC among these two groups were not significantly different (p = 0.47). The Tg levels in the case and control groups were 106 (2.2–6,000) ng/mL and 2.7 (0.3–10.10) ng/mL, respectively (p = 0.0001). TSH level in the case group was 50 (30–107) µIU/mL and in the control was 50 (20–100) µIU/mL (p = 0.224). ATA levels in the case and control groups were 0–3,000 and 0–629 ng/mL, respectively (p = 0.01). The AUC was 0.976 with a 95% confidence interval of 0.924 to 0.996 and a standard error of 0.016. The cut-off value of preradioactive iodine Tg was 10.1 ng/mL or higher with sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of 96.1, 100, 98.0, 100, and 96.2%, respectively.
Conclusion Preradioactive iodine Tg level 10.1 ng/mL or higher can be used as a predictor of metastasis in patients with DTC.
A Prospective Study to Assess Patients' Understanding and Retention of Postoperative Instructions following a Fixed Partial Denture, Using Different Information Delivery Techniques
Authors: Adawi Hafiz , Jain Saurabh , Hakami Aeshah H. , Mtwam Naseem A. , Koriri Almaha Y. A. , Adawi Abdulaziz A. A. 
Published: September 2022

Abstract
Objective This study was aimed to evaluate the effect of using different modes of at-home maintenance information delivery on patients' understanding and the level of information retention.
Materials and Methods Sixty patients were asked to answer a questionnaire while undergoing mouth preparations for receiving a fixed partial denture. The questionnaire includes questions related to at-home maintenance procedures and recall visits. After finishing the first questionnaire, these patients were randomly assigned into three groups, and each group was given education about at-home maintenance procedures and recall visits by different means. Group 1 participants were educated by giving live demonstrations. Group 2 participants were shown a prerecorded video, whereas group 3 participants were given written instructions. All Participants were recalled after 1 week of the last visit and were asked to fill out the same questionnaire.
Statistical Ananlysis Collected data were tabulated in a Microsoft Excel Spreadsheet and were analyzed using the Chi-square test, one-way ANOVA, paired t-test, and post hoc Bonferroni test. A p-Value < 0.05 was regarded as statistically significant for all the analyses.
Results Group 1 showed greatest information retention as compared with groups 2 and 3 (p = 0.045). There was significant difference in the knowledge of group 1 as compared with groups 2 (p = 0.020) and 3 (p = 0.048).
Conclusion The mode of delivering postoperative instructions after fixed partial denture treatment does have an effect on the patient understanding level and information retention. Patients who were given live demonstrations showed the best results compared with video recordings and written leaflets.
Active MMP-8 as a Biomarker of Peri-implant Health or Disease
Authors: Xanthopoulou Vithleem , Räisänen Ismo , Sorsa Timo , Sakellari Dimitra 
Published: September 2022

Abstract
Objectives This study investigated the potential of testing for active matrix metalloproteinase-8 (aMMP-8) by a quantitative point-of-care (PoC), chairside, lateral flow immunotest as a biomarker for the presence or absence of peri-implant diseases.
Materials and Methods Eighty healthy patients with implants were recruited. The samples were collected from peri-implant sulcular fluid and quantitatively analyzed for aMMP-8. Clinical indices, which included probing depth, clinical attachment loss, bleeding on probing, and plaque, were recorded and radiographic assessments were performed.
Statistical Analysis Comparisons of aMMP-8 levels and clinical parameters were analyzed by the Kruskal–Wallis test and the pairwise post hoc Dunn–Bonferroni test. A receiver operating curve analysis was used to analyze the diagnostic ability of aMMP-8 and the correlation between aMMP-8 and probing depth of the sampled site was sought by Spearman's rho and the coefficient of determination (R
2).
Results Statistical analysis revealed statistically significant differences of aMMP-8 levels between the healthy and the mucositis and peri-implantitis groups, and between the mucositis and the peri-implantitis groups. Increasing probing depths of the sampled site and aMMP-8 levels were significantly correlated.
Conclusions These data suggest that the aMMP-8 PoC test can be a beneficial adjunctive tool for early identification and screening of the risk of peri-implant diseases and progression.
Measuring Quality of Life after Venous Thromboembolism: Who, When, and How?
Authors: Tavoly Mazdak , Asady Elia , Wik Hilde Skuterud , Ghanima Waleed 
Published: September 2022

AbstractThere is a growing body of evidence revealing that many patients with a history of venous thromboembolism (VTE) suffer from long-lasting sequelae such as post-thrombotic syndrome and post-pulmonary embolism syndrome. These two syndromes are detrimental to patients as they affect their quality of life (QOL). From this perspective, monitoring QOL may play a crucial role to improve quality care in VTE patients. Many studies have explored possible temporal relations between VTE episodes and decreased functional status and/or QOL. However, studies exploring the implementation of QOL and functional status questionnaires in clinical practice are scarce. In this context, we discuss possible perspectives synthetized from available literature regarding in whom, when, and how QOL could be measured in clinical practice.
Hahnemann's Sick Proving: A Comprehensive Study on Its Working Methodology
Authors: Tiwary Himanshu Sekhar , Tiwary Nidhi 
Published: September 2022

Abstract
Background Homoeopathy operates with highly potentised medicines since, during sickness, there is a state of heightened sensitivity to similar stimuli in an individual. The same proposition is also the guiding principle behind one of the advanced methods of Hahnemann, i.e. sick proving. This tool was employed by Hahnemann in his later life to record the symptoms from sensitive and chronic patients. Unfortunately, this collateral method of drug proving has not been examined thoroughly and hence has not been utilised. This study intends to revisit Hahnemann's sick proving and decipher the finer shades of its working methodology.
Material and Methods A comprehensive literature search and analysis for sick proving was done from Hahnemann's major works such as Organon of Medicine, the Chronic Diseases, Materia Medica Pura and other literature such as lesser writings, redacted writings, letters, biographies and miscellaneous publications. All the proving records of the Chronic Diseases were examined in terms of their source and methodology and analysed from the perspective of sick proving.
Results From the present study, it has distinctly emerged that Hahnemann had a very systemic and methodical process of sick proving observed mainly in unaltering chronic patients. He used to take healthy drug proving symptoms mainly from other sources for his work in the Chronic Diseases and add symptoms from his sick proving as a collateral route. Sick proving was part of follow-up consultation in new as well as extensively proved drugs as evident from the Letter of Hermann Hartlaub in 1834. He added many valuable polychrest drugs in our armamentarium with the help of this method in his book the Chronic Diseases.
Conclusion Unlike healthy drug proving, sick proving by Hahnemann has not been thoroughly investigated despite its sound logic and tangible merits. A more detailed study is required to realise the full potential of this wonderful method of drug proving.
Padrão incomum de impacto marginal osteocondral em fraturas acetabulares: Um relatório de dois casos
Authors: Ibrahim Bahaaeldin , Badran Mahmoud , Khalifa Ahmed A. , Abubeih Hossam , Farouk Osama 
Published: September 2022

ResumoAs fraturas acetabulares podem ser acompanhadas por lesões de impacto articular, afetando os desfechos se não vistas ou tratadas de modo incompleto. A impactação marginal detectada em estudos de imagem pré- ou intraoperatórios deve ser reduzida anatomicamente usando a cabeça femoral como modelo e aumentando o defeito com enxerto ósseo, se necessário. A superfície articular do segmento impactado parece voltada para a frente durante a cirurgia, que é a descrição clássica de tais lesões. No relatório atual, descrevemos um padrão incomum de aparecimento de lesões de impacto marginal em dois pacientes, onde a superfície articular do fragmento impactado está voltado para a cavidade articular, sendo o inverso da descrição clássica, aludindo ao mecanismo provável de sua ocorrência, à técnica de redução e às consequências de ignorar tal lesão. Lesões de impacto marginal devem ser diagnosticadas e tratadas corretamente para preservar a congruência articular; no entanto, o cirurgião deve estar ciente da possibilidade de um padrão incomum de impacto marginal no qual o fragmento poderia ser revertido; manter esta possibilidade em mente facilitaria seu diagnóstico e manejo.
Design and performance of a flexible broadband metamaterial absorbing structure fabricated based on the direct ink writing 3D printing
Authors: Shi Linghui , Xiao Xingzhi , Liu Tingting , Liao Wenhe , Kong Linghui 
Published: September 2022

Abstract
The method of three-dimensional (3D) printing significantly improves the design freedom of absorbing structures as these are fabricated under the layer-by-layer stacking mode. A four-layer gradient woodpile metamaterial absorbing structure (FGWMAS) based on the direct ink writing 3D printing (DIW3DP) is proposed. First, carbonyl iron powder/polydimethylsiloxane, which endows FGWMAS with outstanding flexibility, chemical and thermal stability, is prepared as the absorbing composites. The electromagnetic parameters are measured and used as inputs of the FGWMAS design. Additionally, the correlation is established between DIW3DP process parameters and the cross-sectional dimensions of the woodpile unit cell. Furthermore, the validity of the equivalent medium theory is verified, and it is utilised to realise the rapid design of FGWMAS. The thickness of each layer is optimised using genetic algorithms, and the optimised FGWMAS is obtained. The simulation results reveal that the maximum effective absorbing bandwidth of the proposed FGWMAS is up to 12.15 GHz (5.85–18 GHz) in the 1–18 GHz band range, and the minimum reflectivity is −37.91 dB at 10.95 GHz. This paper provides a new design and manufacturing method for metamaterial absorbing structures with micro unit cells. The DIW3DP flexible metamaterial absorbing structure has strong potential for conformal, low-cost, and customised application.
Modulating the microscopic lattice distortions through the Al-rich layers for boosting the ferroelectricity in Al:HfO2 nanofilms
Authors: Yao Lulu , Das Sambit , Liu Xin , Wu Kai , Cheng Yonghong , Gavini Vikram , Xiao Bing 
Published: September 2022

Abstract
Combining the experimental characterization with the large-scale density functional theory calculations based on finite-element discretization (DFT-FE), we address the stabilization of polar orthorhombic phases (o-HfO2) in Al:HfO2 nanofilms by means of the atomic registry distortions and lattice deformation caused by Al substitutional defects (AlHf) and Schottky defects (2AlHf + VO) in tetragonal phases (t-HfO2) or monoclinic phases (m-HfO2). The phase transformation directly from the t-HfO2 into polar o-HfO2 are also elucidated within a heterogeneous distribution of Al dopants in both t-HfO2 bulk crystal structure and Al:HfO2 nanofilm. It is revealed using large-scale DFT calculations that the Al substitutional defects (AlHf) or the Schottky defect (2AlHf + VO) could induce the highly extended atomic registry distortions or lattice deformation in the t- and m-HfO2 phases, but such effects are greatly diminished in ferroelectric orthorhombic phase. By purposely engineering the multiple AlHf defects to form dopant-rich layers in paraelectric t-HfO2 nanofilm or bulk crystal, the induced extended lattice distortions surrounding the defect sites exhibit the shearing-like atomic displacement vector field. The large-scale DFT calculations further predicted that the shearing-like microscopic lattice distortions could directly induce the phase transformation from the t-HfO2 into polar orthorhombic phase in both Al:HfO2 bulk crystal and nanofilms, leading to the large remanent polarization observed in Al:HfO2 nanofilms with the presence of Al-rich layers. The current study demonstrates that the ferroelectricity of HfO2 bulk crystal or thin film can be optimized and tuned by delicately engineering both the distribution and concentration of Al dopants in atomic layer deposition without applying the top capping electrode, providing the extra flexibility for designing the HfO2 based electronic devices in the future.
Investigation on dislocation and deflection morphology of PVT-grown on-axis 4H-SiC crystals
Authors: Li Huadong , Peng Yan , Yang Xianglong , Xie Xuejian , Chen Xiufang , Hu Xiaobo , Xu Xiangang 
Published: September 2022

Abstract
The morphologies of dislocation etch pits and dislocation deflections of on-axis 4H-SiC substrate etched by molten KOH were observed with the help of a microscope. Based on experimental observation and etch mechanism, a method for the identification of threading edge dislocations, threading screw dislocations (TSDs) and threading mixed dislocations was proposed. The details about the inner micro-structure of threading edge dislocations and TSDs were observed by laser scanning confocal microscope and scanning electron microscopy. The morphologies and the cross-sectional views of the basal plane dislocation formed by threading edge dislocation were observed and two models were formed to explain it.
Energy evolution of the overlap functions: increasing ratio of σ
el(s)/σ
tot(s) and black ring emergence
Authors: Troshin S M , Tyurin N E 
Published: September 2022

Abstract
We consider two possible options of the energy dependency of the elastic and inelastic overlap functions. Those correspond to saturation of the black disk limit (BEL effect) and to the unitarity saturation (REL effect) at s → ∞. Relation of the REL effect to increase of the ratio σ
el(s)/σ
tot(s) and emergence of black ring picture at the LHC is underlined.