bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hybrid Synthesis of bioplastics polyhydroxybutyrate from carbon dioxide
Authors: Zhang Jie , Liu Dingyu , Liu Yuwan , Chu Huanyu , Cheng Jian , Zhao Haodong , Fu Shaoping , Huihong Liu , Fu YuE , Ma Yanhe , Jiang Huifneg 
Published: October 2022

AbstractThe accelerating environmental crisis has intensified the demand for switching from traditional economy to a renewable one with a reduced carbon footprint. Here we reported a hybrid system, coupling chemical process of CO2hydrogen reduction and biological process for polyhydroxybutyrate (PHB) synthesis, that utilized CO2as a raw material to produce PHB in vitro. The synthetic pathway of PHB was optimized by screening more efficient methanol oxidases, high activity mutants of glycolaldehyde synthase and coordinating enzyme dosages in the pathway, which achieved the carbon yield of 93.6% for producing PHB from methanol. Finally, by combining with the chemical process from CO2to methanol, a scaling-up bio-system was performed to convert CO2into PHB, yielding 5.8 g/L with the productivity of 1.06 g-1L-1h-1. This approach represents a promising carbon-neutral way to produce biodegradable plastics.
A Zur-mediated transcriptional regulation of the zinc export system
Authors: Ducret Verena , Gonzalez Diego , Leoni Sara , Valentini Martina , Perron Karl 
Published: October 2022

AbstractThe control of cellular zinc (Zn) concentrations by dedicated import and export systems is essential for the survival and virulence ofPseudomonas aeruginosa. The transcription of its many Zn transporters is therefore tightly regulated by a known set of transcription factors involved in either the import or the export of Zn. In this work, we show that the Zur protein, a well-known repressor of Zn import, plays a dual role and functions in both import and export processes. In a situation of Zn excess, Zur represses Zn entry, but also activates the transcription ofczcR, a positive regulator of the Zn export system. To achieve this, Zur binds at two sites, located by DNA footprinting in the region downstream theczcRtranscription start site. In agreement with this regulation, a delay in induction of the efflux system is observed in the absence of Zur and Zn resistance is affected. The discovery of this regulation highlights a new role of Zur as global regulator of Zn homeostasis inP. aeruginosadisclosing an important link between Zur and zinc export.
Dynamic compartmentalization of the pro-invasive transcription factor NHR-67 reveals a role for Groucho in regulating a proliferative-invasive cellular switch inC. elegans
Authors: Medwig-Kinney Taylor N. , Kinney Brian A. , Martinez Michael A. Q. , Yee Callista , Sirota Sydney S. , Mullarkey Angelina A. , Somineni Neha , Hippler Justin , Zhang Wan , Shen Kang , Hammell Christopher M. , Pani Ariel M. , Matus David Q. 
Published: October 2022

AbstractA growing body of evidence suggests that cell division and basement membrane invasion are mutually exclusive cellular behaviors. How cells switch between proliferative and invasive states is not well understood. Here, we investigated this dichotomyin vivoby examining two cell types in the developingCaenorhabditis eleganssomatic gonad that derive from equipotent progenitors, but exhibit distinct cell behaviors: the post-mitotic, invasive anchor cell and the neighboring proliferative, non-invasive ventral uterine (VU) cells. We show that the fates of these cells post-specification are more plastic than previously appreciated and that levels of NHR-67 are important for discriminating between invasive and proliferative behavior. Transcription ofnhr-67is downregulated following post-translational degradation of its direct upstream regulator, HLH-2 (E/Daughterless) in VU cells. In the nuclei of VU cells, residual NHR-67 protein is compartmentalized into discrete punctae that are dynamic over the cell cycle and exhibit liquid-like properties. By screening for proteins that colocalize with NHR-67 punctae, we identified new regulators of uterine cell fate maintenance: homologs of the transcriptional co-repressor Groucho (UNC-37 and LSY-22), as well as the TCF/LEF homolog POP-1. We propose a model in which association of NHR-67 with the Groucho/TCF complex suppresses the default invasive state in non-invasive cells, which complements transcriptional regulation to add robustness to the proliferative-invasive cellular switchin vivo.
Interactions between architects and end-users during housing design processes: a systematic literature review
Authors: Mertens Audrey , Hamarat Yaprak , Elsen Catherine 
Published: October 2022

PurposeThis research focuses on the interactions between architects and end-users during the design process of housing projects, both experiencing challenges and friction points when meeting.Design/methodology/approachThe authors conducted a systematic literature review (SLR), based on and adapted from Kitchenham and Charters' work (2007). The thematic analysis of N = 104 identified articles reveals 13 main themes and 30 subthemes specific to architects, end-users and the interactions of architects and end-users, and 3 main groups of other actors intervening in these dynamics. The authors organize the data by actors and the actors' social encounters, themes and subthemes. The authors focus on some aspects, given possible evolution of practices.FindingsThe authors question the role of architects and the ways both parties share respective knowledge. The authors also discuss the various scales of social encounters depicted through literature, from traditional discursive meetings to participatory practices, and raise the lack of convincing tools genuinely used in current housing architecture practices. Finally, the authors point out the need for further field research in order to practically bridge the gap between researchers and practitioners.Originality/valueThe authors present an overview of the most relevant papers, organized in a table and grouped by themes. This represents a major output of this SLR, and gives the concerned readers the opportunity to get a grasp on readers' sub/theme of interest.
Impact of boredom on perceived inequity and discretionary behaviors: a latent growth curve approach
Authors: Chou Shih Yung , Han Bo , Ramser Charles 
Published: October 2022

PurposeThis study seeks to examine the effect of work-related boredom and a perceived lack of external stimulation on benevolent and entitled employees' perceived inequity and discretionary workplace behaviors.Design/methodology/approachA total of 668 useable three-wave panel data were obtained via Amazon Mechanical Turk during a three-month period. The hypothesized model was tested using a latent growth curve modeling via EQS 6.4 for Windows.FindingsThis study finds the following results. First, benevolent employees who experience higher initial work-related boredom report positive inequity. Second, entitled employees who experience higher initial work-related boredom and a perceived lack of external stimulation report negative inequity. Third, increases in work-related boredom and a perceived lack of external stimulation result in a faster increase in entitled employees' perceived negative inequity. Fourth, entitled employees who perceive higher negative inequity at the initial measurement period report higher interpersonal deviance. Finally, increases in entitled employees' perceived negative inequity result in a faster increase in interpersonal deviance.Originality/valueThis study highlights how employees may assess their effort and rewards when experiencing boredom. This study also offers some practical recommendations that help human resource managers manage boredom in the organization effectively.
The role of EU funding in EU member states: building administrative capacity to advance administrative reforms
Authors: Nakrošis Vitalis , Dan Sorin , Goštautaitė Rasa 
Published: October 2022

PurposeDespite the growing volume of European Union (EU) investments into reforms and public administration, how EU support contributes to administrative reform and capacity building at domestic level is still unclear. The article explains the EU's influence, domestic politicisation and previous administrative capacity on organisational change whilst implementing European Social Fund-financed projects during the programming period 2014–2020.Design/methodology/approachBy going beyond the EU-centred approach and based on different strands of the new institutionalism, the authors offer three explanations on the influence of EU support. The authors performed the qualitative content analysis of 29 case studies and matched the implementation of the projects with the authors' explanations.FindingsThe authors' research results indicate that progress in the implementation of the projects was determined by domestic factors rather than EU conditionalities. The influence of domestic politicisation was found to be mixed, but higher levels of initial administrative capacity proved to be most important to achieving organisational change.Research limitations/implicationsThe authors' judgement of the project implementation and their success was based on the information provided in the case studies at the time of implementation.Practical implicationsThe authors' research points to the essential need for the initial and gradual development of administrative capacity to achieve good reform results.Originality/valueBased on the different logics of the new institutionalism, we developed specific mechanisms for organisational change. The authors' research results deepen the understanding of how politicisation positively or negatively shapes reform implementation, as well as how pre-existing administrative capacity and further development of pre-existing administrative capacity dynamically occurs through a process of socialisation and learning.
Application of the stereotype content model in marketing: a three-level review and future research
Authors: Guo Xiaoling , Liu Hao , Zhang Yicong 
Published: October 2022

PurposeThe aim of this research is to examine the application of the stereotype content model (SCM) in the field of marketing from macro (the country of origin), meso- (corporate image) and micro (service providers, brands, advertising and promotions) levels.Design/methodology/approachThis paper collects, reviews and summarizes the relevant literature, and prospects future research directions from three levels on this research topic.FindingsFirst, the authors contend that competence primacy popularizes in the early work but warmth becomes more influential recently. Second, they identify and discuss two doubts of the SCM in marketing, namely the moral dimension and the link between brands as intentional agents framework (BIAF) and the brand personality theory. Finally, they suggest several research avenues for the use of SCM in marketing research, including research on nation branding, emerging global brands and Confucianist cultures at macro level, artificial intelligence and warmth-as-competence strategy at meso-level, and brand personality and the brand animal logo at micro level.Originality/valueAs an established framework in social psychology, the SCM has been increasingly applied in marketing research and a literature review in this light appears timely. This paper conducts for the first time a comprehensive review of the SCM in the marketing field on three levels, projects promising research directions, and thus contributes to the academia of marketing.
Between progress and struggle: young PR-scholars’ contribution to theory building and progress in public relations research
Authors: Seiffert-Brockmann Jens , Hackl Laura , Ihlen Øyvind 
Published: October 2022

PurposeThe paper aims to analyze the contribution of young academics to the field of public relations (PR) and shows which authors exert most influence on them. The study thereby contributes to the assessment of the state of the art of theory building in the field. The authors analyzed the study data against the background of two approaches on progress in the field: Nothhaft et al.’s (2018) idea of strategic communication as an elusive concept and Winkler et al.’s (2021) narrative approach.Design/methodology/approachThe study comprises two parts. First, the authors conducted a survey among participants of the EUPRERA PhD-workshops between 2007 and 2019, asking respondents about their perception of the state of the field. Second, the authors performed a bibliometric (co-)citation analysis of the young scholars’ most important works.FindingsResults indicate that though the field has progressed in terms of quantity and diversified with regard to established paradigms, it has not matured in a sense that it has settled on a generally accepted theoretical underpinning. However, the data show how the dominant paradigms in the field map onto the co-citation networks that emerged out of the works of young scholars. The authors’ findings imply that this new generation might signal their allegiance to a paradigm by citing the works of its emblematic authors.Originality/valueUnlike most bibliometric studies, this one uses an author-centered approach, thus studying works that matter most to young academics themselves. Not only do the authors thereby contribute to the analysis of the state of theory building in PR research, but also expand the scope in looking at research as a social system, in which young researchers need to position themselves.
Construction planning through 4D BIM-based virtual reality for light steel framing building projects
Authors: Rashidi Ali , Yong Wei Yin , Maxwell Duncan , Fang Yihai 
Published: October 2022

PurposeThe construction industry has actively attempted to tackle the low-productivity issues arising from inefficient construction planning. It is imperative to understand how construction practitioners perceive technology integration in construction planning in light of emerging technologies. This study intended to uncover unique experimental findings by integrating 4D-building information modelling (BIM) to virtual reality (VR) technology during construction planning among construction professionals at light steel framing (LSF) projects.Design/methodology/approachThe building industry participants were invited to provide inputs on two different construction planning methods: conventional and innovative methods. The conventional method involved the participants using traditional platforms such as 2D computer-aided design (CAD) and physical visualisation of paper-based construction drawings for the LSF assembly process with a Gantt Chart tool to complete construction planning-related tasks for the targeted project. Comparatively, participants are required to perform the same tasks using more innovative platforms like 4D-BIM in a VR environment.FindingsA Charrette Test Method was used to validate the findings, highlighting an improvement in usability (+10.3%), accuracy (+89.1%) and speed (+30%) using 4D BIM with VR compared to the conventional paper-based method. The findings are also validated by a paired t-test, which is supported by the rationality of the same findings. This study posits positive results for construction planning through the utilisation of modern practices and technologies. These findings are significant for the global construction industry facing low productivity issues, delays and certainty in terms of building delivery timelines due to poor construction planning.Originality/valueThis new blend of technologies—combining 4D BIM and VR in industrialised construction projects—potentially directs future initiatives to drive the efficiency of construction planning in the building lifecycle. The interactive BIM-based virtual environment would purposefully transform construction planning practices in order to deliver modern and more certain building construction methods with a focus on prefabrication processes.
A multicomponent approach to studying cultural propensities during foraging in the wild
Authors: Mannion Kelly Ray , Ballare Elizabeth F. , Marks Markus , Gruber Thibaud 
Published: October 2022

Abstract

Determining the cultural propensities or cultural behaviours of a species during foraging entails an investigation of underlying drivers and motivations.

In this article, we propose a multicomponent approach involving behaviour, ecology, and physiology to accelerate the study of cultural propensities in the wild.

We propose as the first component the use of field experiments that simulate natural contexts, such as foraging behaviours and tool use opportunities, to explore social learning and cultural tendencies in a variety of species. To further accelerate this component, we discuss and advocate for the use of modern machine learning video analysis tools.

In conjunction, we examine non‐invasive methods to measure ecological influences on foraging such as phenology, fruit availability, dietary intake; and physiological influences such as stress, protein balance, energetics, and metabolism. We feature non‐invasive urine sampling to investigate urea, creatinine, ketone bodies, the thyroid hormone triiodothyronine (T3), cortisol and connecting peptides of insulin.

To conclude, we highlight the benefits of combining ecological and physiological conditions with behavioural field experiments. This can be done across wild species, and provides the framework needed to test ecological hypotheses related to cultural behaviour.
Expressivist objections to prenatal screening and testing: Perceptions of people living with disability
Authors: Boardman Felicity , Thomas Gareth 
Published: October 2022

AbstractThe ‘expressivist objection’ (EO) refers to the notion that using reproductive (genetic) technologies to prevent the birth of future would‐be disabled people contain, and express, a negative valuation of life with disability. Whilst the EO has received increased attention in recent years in line with rapid technological and genomic developments, there remains scant research on how EO concerns are experienced and expressed by disabled people and their families, especially within and between impairment groups. Bringing together two studies—one with adults and family members living with genetic conditions (n = 62) and one with parents of children with Down’s syndrome (n = 22)—we argue that disabled people and their families variously embrace, reject or rework the EO across contexts, and yet also frequently situate it within broad support for reproductive technologies. We present three key factors that mediate responses to the EO: (1) the nature of impairment and its integration within identity; (2) social and cultural contexts relating to disability and (3) the (individual and collective) imagined futures of disabled people. In so doing, we blend the conceptual architecture of medical sociology and disability studies, arguing that this allows us to accurately illuminate the nuanced responses of disabled people and their families.
The diagnostic and prognostic utility of serum cystatin C and angiopoietin 2 in patients with liver cirrhosis complicated by acute kidney injury
Authors: Abd El Wahab Ahmed M. , Awadeen Abeer , Mansour Mostafa M. , Shemies Rasha 
Published: October 2022

AbstractBackgroundAcute kidney injury (AKI) frequently affects patients with liver cirrhosis, diagnosed by changes in serum creatinine and urine output. This study aimed to evaluate the diagnostic and prognostic utility of serum cystatin C (Cys C) and angiopoietin 2 (Ang 2) in patients with liver cirrhosis complicated by AKI.MethodsA total of 81 cirrhotic patients with AKI were included. AKI was diagnosed according to Kidney Disease Improving Global Outcomes criteria. All patients were assessed clinically and biochemically. Baseline serum Cys C and Ang 2 were assessed, and patients were prospectively followed‐up to assess patients' and renal survival.ResultsCys C significantly predicted AKI (p < 0.001). Ang 2 (≤179.7 pg/ml) was an independent predictor of mortality in multivariate analysis. Marked ascites and partial pressure of carbon dioxide ≤ 29 were significant predictors of nonrenal recovery.ConclusionCys C showed validity AKI diagnosis in cirrhotic patients while Ang 2 was an independent predictor of mortality.
Quality improvement of gluten‐free rice flour bread through the addition of high‐temperature water during processing
Authors: Saito Kumiko , Okouchi Maya , Yamaguchi Mana , Takechi Tayori , Hatanaka Yoshiro , Kitsuda Koji , Mannari Takayo , Takamura Hitoshi 
Published: October 2022

AbstractRecently, there has been an increase in the demand for gluten‐free bread due to health reasons. One of the flours used to produce gluten‐free bread is rice flour; flour characteristics are very important for breadmaking. Although a study has shown that the addition of high‐temperature water can improve the quality of rice flour bread, studies are yet to consider different rice properties. Therefore, the aim of this study was to investigate the effect of adding high‐temperature water and rice flour characteristics on the quality of rice flour bread using six commercially available rice flours. The rice flours used in the sample had amylose content from 12.1% to 24.5%, damaged starch content from 2.4% to 5.5%, mode diameter from 16.3 to 63.3 µm, protein content from 5.4% to 6.1%, and moisture content in the range of 12.0%–15.0%. The results showed that regardless of the rice characteristics, breads prepared at the optimum watering temperature were puffier and softer than those prepared using cold water (5°C). For rice flours with similar particle size, the optimal water temperature and degree of gelatinization for breadmaking increased with rice flours with lower amylose content. Furthermore, the rheological properties of dough prepared at the optimum water addition temperature were stable, with loss modulus (G″) being dominant over the entire frequency range in the frequency sweep test. Since the water temperature added to the dough affects breadmaking properties more than the characteristics of the rice flour, adjusting the water temperature may enable the production of high‐quality bread even with rice flour unsuitable for making.Practical ApplicationPresently, the addition of high‐temperature water to rice flour has been shown to improve the bread quality. In this study, we investigated the effects of high‐temperature water addition on the quality of rice flour bread using rice flour varieties with different flour characteristics. Even in rice flour with small particle size and low amylose content, which is not suitable for breadmaking, bread quality can be improved by adding hot water at around 70°C. This is a simple and practical method to improve the quality of gluten‐free rice flour bread without adding thickeners.