bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk‐based serological survey of bluetongue and the first evidence of bluetongue virus serotype 26 circulation in Tunisia
Authors: Sana Kalthoum , Soufien Sghaier , Thameur Ben Hassine , Liana Teodori , Massimo Spedicato , Kaouther Guesmi , Raja Gharbi , Haikel Hajlaoui , Bassem Bel Haj Mohamed , Wiem Khalfaoui , Monia Lachtar , Ameni Ben Salem , Naouel Fatnassi , Anissa Dhaouadi , Mehdi Ben Ali , Sarah Thabet , Chedia Seghaier , Giovanni Savini , Salah Hammami 
Published: May 2022

AbstractBackgroundBluetongue (BT), a vector‐borne disease of wild and domestic ruminants, is responsible for severe economic losses in flocks. To reduce this impact, a surveillance and control plan was implemented in Tunisia. However, the epidemiological situation of BT remains incompletely understood, especially for the circulating serotypes.ObjectiveThe aim of this survey was to determine the seroprevalence, to identify the circulating serotypes and to identify the associated risk factors for bluetongue virus (BTV) circulation in Tunisia using risk‐based sampling (RBS).MethodsA total of 3314 blood samples were randomly collected from 67 sectors using risk‐based sampling and screened by competitive enzyme‐linked immunosorbent assays (c‐ELISAs). Out of the 1330 positive samples, 200 samples were analysed by serum neutralization test (SNT) to identify circulating BTV serotypes.ResultsOf 3314 sera, 1330 were c‐ELISA‐positive (40.1%) for antibodies against the BTV structural protein VP7. The result of SNT showed the presence of BTV‐1, BTV‐2, BTV‐3, BTV‐4 and, for the first time in Tunisia, BTV‐26. The logistic regression model revealed that older animals had nearly two times the odds of being infected with BTV compared to younger animals. Flocks with a history of BT were almost 1.5 times more likely to be at risk for contracting BTV infection. The flock size, housing indoors and intensive production system were significant protective factors.ConclusionsHigh seroprevalence of BTV among sheep was highlighted in Tunisia. The neutralization test showed the presence of the following BTV serotypes: BTV‐1, BTV‐2, BTV‐3, BTV‐4 and, for the first time in Tunisia, BTV‐26. Age, production system and flock size were important variables associated with BTV infection in sheep. This finding is crucial, as it will allow the adjustment of the BT control programme in Tunisia.
Disorders of the sustentaculum tali and the medial trochlear ridge of the talus in horses: Novel findings and surgical management of five cases
Authors: Della Tommasa Simone , Scharner Doreen , Brehm Walter , Troillet Antonia 
Published: May 2022

AbstractThe sustentaculum tali (ST) is located at the medial aspect of the tarsus and is considered a rare anatomic location for diseases. This retrospective case series describes the management of five horses with septic and non‐septic ST injuries. All horses were treated surgically with tenovaginoscopy, ST fragment and exostosis removal. In two cases, lameness was caused by an exostosis involving the ST and the plantar aspect of the medial trochlear ridge (MTR). There are no reports of exostosis involving ST and MTR causing lameness. In four horses, the long‐term outcome was considered good and the horses were able to return to the previous level; one horse developed a recurrence of ST and MTR exostosis leading to recurrence of lameness. Curettage of the ST and MTR exostosis, removal of fragments and tarsal sheath adhesions play a pivotal role in increasing prognosis and long‐term outcome. Poor prognosis is correlated with exostosis recurrence.
Prevalence of lymphoproliferative disease virus in wild turkeys (Meleagris gallopavo) in North Carolina
Authors: Kreh Christopher D. , Palamar Maria B. 
Published: May 2022

AbstractLymphoproliferative disease virus (LPDV) is a highly prevalent pathogen first described from wild turkeys (Meleagris gallopavo) in 2009, with uncertain implications for wild turkey populations. To establish a baseline of its prevalence and geographic distribution, we gathered LPDV samples across North Carolina, USA, from 2 age classes of wild turkeys in 2013 and 2015. We collected 829 tissue samples, primarily from hunter harvests, and tested for presence of LPDV via polymerase chain reaction (PCR). The overall prevalence of LPDV was 46.1% (382 of 829 turkeys). Prevalence was significantly lower in juveniles than adults (29.7% and 48.4% respectively [χ2 = 13.52, df = 1, P < 0.001]). Prevalence of LPDV in adult turkeys was greater in the mountain region than in either the piedmont or coastal regions. Prevalence of LPDV did not vary between years (χ2 = 1.47, df = 1, P = 0.26) or sexes (χ2 = 0.06, df = 1, P = 0.81). Mean weights of LPDV‐positive adult male turkeys (8.9 kg) and LPDV‐negative adult male turkeys (8.9 kg) were not different. We observed no correlation between LPDV prevalence and reported turkey harvest, nor between LPDV prevalence and productivity estimates from our annual summer brood survey. Our work is consistent with previous reports that LPDV is a widespread virus in wild turkeys that differs in prevalence across ages and regions. Further investigation of LPDV's effect on turkey poults and transmission of the pathogen among juvenile and adult turkeys is needed.
Whole-Body Hyperthermia (WBH): Historical Aspects, Current Use, and Future Perspectives
Authors: Heckel-Reusser S. 
Published: May 2022

AbstractWhole-body hyperthermia (WBH), induced by passive heating, and active fever therapy induced by pyrogenic drugs, have been accepted as therapy of various diseases for many decades. However, the introduction of antibiotics and anti-inflammatory drugs caused the interest in this traditional therapy to decline. The development of modern WBH using infrared irradiation (IR) started in the 1960s.Three levels of hyperthermia differ fundamentally in practical implementation, mechanisms of action, and indications. Mild WBH is stress-free and aims mainly to muscle relaxation and increased perfusion in the locomotor system. Fever-range whole-body hyperthermia (FRWBH) requires a more extensive nursing care due to major thermoregulatory stress. FRWBH is applied for stimulation of anti-tumor immune responses and for anti-inflammatory effects in case of chronic inflammation. Moreover, anti-depressive effects of FRWBH could recently be shown. Extreme WBH needs an intensive care environment and aims to the direct damage of cancer cells or therapy-resistant pathogens. In general, inconsistent effects of WBH on blood perfusion must be taken into account if combined with medication.Two commercially available medical WBH devices both use water-filtered infrared-A (wIRA), but deviate in the practical implementation. Contraindications and the risk of side effects differ essentially between the three levels and must carefully be observed.
The New Natural State of the Market
Authors: Holthe Einar Kleppe 
Published: May 2022

Abstract
A New Natural State of the Market, The economic consequence of Awareness. The market ideological appraoch of Natural State is suggesting a more meaningful holistic, and neutral value perspective and methodolgy for value creation. Where a new natural state of the world markets can be obtain with a, spheric and new economic language for the future and aware market. Sustainability over time must become the core market ideal for fostering a sustainable global market culture as key to make sustainability the core quality in any value creation and value transactions, in any value chain, value system or value-spheres for the transparent and aware market spheres of the 21th. century. As a contribution to the second Kyoto Economic Manifesto. The Natural State-theory of market-and value spheres represents a market ideological and practical approach to seek a, more natural and holistic value perspective to secure sustainable value development in any kind of places, markets and aware economis.
Gravitational quasinormal modes for Lifshitz black branes
Authors: Andrade Tomas , Pantelidou Christiana 
Published: May 2022

Abstract
We study the scalar and vector channels of gravitational quasinormal modes for Lifshitz black branes emerging in Einstein-Maxwell-Dilaton and Einstein-Proca theories in four and five dimensions, finding significant differences between the two models. In particular, rather surprisingly, in the Einstein-Maxwell-Dilaton model the dispersion relations for the shear and sound modes are given by ωshear ∼ −i k4 and ωsound ∼ −i k2, while in the Einstein-Proca model they take the more conventional form ωshear ∼ −i k2 and ωsound ∼ k —the proportionality constants depend on the dynamical exponent and the appropriate factors of temperature. Through the holographic duality, this calculation provides information about the relaxation of the momentum and energy flux operators in a putative dual Lifshitz field theory. Comparing with the dispersion relations obtained directly by considering Lifshitz hydrodynamics suggest that the mass density of the equilibrium state in the Einstein-Maxwell-Dilaton model is infinite.
Detecting few-body quantum chaos: out-of-time ordered correlators at saturation
Authors: Marković Dragan , Čubrović Mihailo 
Published: May 2022

Abstract
We study numerically and analytically the time dependence and saturation of out-of-time ordered correlators (OTOC) in chaotic few-body quantum-mechanical systems: quantum Henon-Heiles system (weakly chaotic), BMN matrix quantum mechanics (strongly chaotic) and Gaussian random matrix ensembles. The growth pattern of quantum-mechanical OTOC is complex and nonuniversal, with no clear exponential regime at relevant timescales in any of the examples studied (which is not in contradiction to the exponential growth found in the literature for many-body systems, i.e. fields). On the other hand, the plateau (saturated) value of OTOC reached at long times decreases with temperature in a simple and universal way: exp(const./T2) for strong chaos (including random matrices) and exp(const./T) for weak chaos. For small matrices and sufficiently complex operators, there is also another, high-temperature regime where the saturated OTOC grows with temperature. Therefore, the plateau OTOC value is a meaningful indicator of few-body quantum chaos. We also discuss some general consequences of our findings for the AdS/CFT duality.
The $$ \overline{\mathrm{MS}} $$-scheme $$ {\alpha}_s^5 $$ QCD contributions to the Adler function and Bjorken polarized sum rule in the Crewther-type two-fold {β}-expanded representation
Authors: Goriachuk I. O. , Kataev A. L. , Molokoedov V. S. 
Published: May 2022

Abstract
We consider the two-fold expansion in powers of the conformal anomaly and of the strong coupling αs for the non-singlet contributions to Adler D-function and Bjorken polarized sum rule calculated previously in the $$ \overline{\mathrm{MS}} $$

MS
¯

-scheme at the four-loop level. This representation provides relations between definite terms of different loop orders appearing within the {β}-expansion of these quantities. Supposing the validity of this two-fold representation at the five-loop order and using these relations, we obtain some $$ \mathcal{O} $$
O
($$ {\alpha}_s^5 $$

α
s
5

) corrections to the D-function, to the R-ratio of e+e−-annihilation into hadrons and to Bjorken polarized sum rule. These corrections are presented both analytically in the case of the generic simple gauge group and numerically for the SU(3) color group. The arguments in the favor of validity of the two-fold representation are given at least at the four-loop level. Within the {β}-expansion procedure the analytical Riemann ζ4-contributions to the five-loop expressions for the Adler function and Bjorken polarized sum rule are also fixed for the case of the generic simple gauge group.
Monic Bivariate Polynomials on Quadratic and q-Quadratic Lattices
Authors: Area I. , Tefo Y. Guemo 
Published: May 2022

AbstractMonic families of bivariate Askey–Wilson polynomials and q-Racah polynomials are explicitly given. Monic families of bivariate orthogonal polynomials, both in quadratic and q-quadratic lattices, are also explicitly given using appropriate limit relations.
Generalized q-Bernoulli Polynomials Generated by Jackson q-Bessel Functions
Authors: Eweis S. Z. H. , Mansour Z. S. I. 
Published: May 2022

AbstractIn this paper, we introduce the polynomials $$B^{(k)}_{n,\alpha }(x;q)$$

B

n
,
α

(
k
)

(
x
;
q
)

generated by a function including Jackson q-Bessel functions $$J^{(k)}_{\alpha }(x;q)$$

J
α

(
k
)

(
x
;
q
)

$$ (k=1,2,3),\,\alpha >-1$$

(
k
=
1
,
2
,
3
)
,

α
>
-
1

. The cases $$\alpha =\pm \frac{1}{2}$$

α
=
±

1
2

are the q-analogs of Bernoulli and Euler$$^{,}$$

,

s polynomials introduced by Ismail and Mansour for $$(k=1,2)$$

(
k
=
1
,
2
)

, Mansour and Al-Towalib for $$(k=3)$$

(
k
=
3
)

. We study the main properties of these polynomials, their large n degree asymptotics and give their connection coefficients with the q-Laguerre polynomials and little q-Legendre polynomials.
A sustainable approach for the stability study of psychotropic substances using vitreous humor and liver as alternative matrices
Authors: Wójtowicz Anna , Reciak Marcin , Nowak Paweł Mateusz , Wietecha-Posłuszny Renata 
Published: May 2022

AbstractThe stability of psychotropic substances representing various drug groups important from the perspective of forensic chemistry, including benzodiazepines, antidepressants, carbamazepine, cocaine, and their selected metabolites, was investigated for 1 month in two alternative biological matrices, vitreous humor and liver homogenate. Three different thermal storage conditions (−20, 4, and 20 °C) were tested. Liquid chromatography-mass spectrometry (LC-MS) analysis was preceded by an effective solid-phase microextraction (SPME) procedure. The results were statistically analyzed using one-way ANOVA to find significant concentration variations over time. The results obtained allowed for dividing the analytes into four groups: stable under all tested conditions, only at −20 and 4 °C, only at 20 °C, and overall unstable. Nordiazepam, venlafaxine, and cocaine and its metabolites turned out to be the most unstable substances, while fluoxetine showed the highest storage stability in both matrices. The SPME/LC-MS method was comprehensively evaluated according to the principles of white analytical chemistry (WAC), which reconcile the greenness and functionality of the method. A close to 100% whiteness score proves its sustainability and suitability for the intended application.
Graphical abstract
Voxel-wise lesion mapping of restless legs syndrome in multiple sclerosis
Authors: Fröhlich Kilian , Knott Michael , Hock Stefan , Dörfler Arnd , Seifert Frank , Winder Klemens 
Published: May 2022

Abstract
Objective
Restless legs syndrome (RLS) is known to be associated with multiple sclerosis (MS) and may be caused by MS lesions in specific cerebral brain regions. Applying a voxel-wise lesion analysis, we tried to identify the contribution of cerebral MS lesions to RLS.

Methods
In this retrospective study, we established a cohort of people with MS with documented RLS and controls of people with MS without RLS matched disease severity. Diagnosis of MS and RLS was based on the current guidelines. The MS lesions were analyzed on T2-weighted magnetic resonance imaging scans (1.5 or 3 T). After manual delineation, lesion maps were converted into stereotaxic space. We generated a lesion overlap and performed a Liebermeister test with 4000 permutations to compare the absence or presence of RLS voxel-wise between patients with and without lesions in a given voxel.

Results
Forty of the patients with RLS and MS fulfilled the inclusion criteria. The voxel-wise analysis yielded associations between RLS and MS in the subcortex of the left gyrus precentralis.

Conclusion
Our voxel-wise analysis shows associations in the subcortex of the left gyrus precentralis. Thus, our data suggests that a dysfunction of the efferent motor system due to cerebral lesions may contribute to the pathophysiology of RLS in MS.
Propagation of barotropic Kelvin waves around Antarctica
Authors: Webb David J. , Holmes Ryan M. , Spence Paul , England Matthew H. 
Published: May 2022

AbstractBarotropic (i.e., depth-uniform) coastal oceanic Kelvin waves can provide rapid teleconnections from climate and weather events in one location to remote regions of the globe. Studies suggest that barotropic Kelvin waves observed around Antarctica may provide a mechanism for rapidly propagating circulation anomalies around the continent, with implications for continental shelf temperatures along the West Antarctic Peninsula and thus Antarctic ice mass loss rates. However, how the propagation of Kelvin waves around Antarctica is influenced by features such as coastal geometry and variations in bathymetry remains poorly understood. Here we study the propagation of barotropic Antarctic Kelvin waves using a range of idealized model simulations. Using a single-layer linear shallow water model with 1∘ horizontal resolution, we gradually add complexity of continental configuration, realistic bathymetry, variable planetary rotation, and forcing scenarios, to isolate sources and sinks of wave energy and the mechanisms responsible. We find that approximately 75% of sub-inertial barotropic Kelvin wave energy is scattered away from Antarctica as other waves in one circumnavigation of the continent, due mostly to interactions with bathymetry. Super-inertial barotropic Kelvin waves lose nearly 95% of their energy in one circumpolar loop, due to interactions with both coastal geometry and bathymetry. These results help to explain why only sustained signals of low-frequency resonant barotropic Kelvin waves have been observed around Antarctica, and contribute to our understanding of the role of rapid, oceanic teleconnections in climate.
Improving brain B0 shimming using an easy and accessible multi-coil shim array at ultra-high field
Authors: Boer Vincent Oltman , Pedersen Jan Ole , Arango Nick , Kuang Irene , Stockmann Jason , Petersen Esben Thade 
Published: May 2022

Abstract
Object
Improve shimming capabilities of ultra-high field systems, with addition of an accessible low-complexity B0 shim array for head MRI at 7 T.

Materials and methods
An eight channel B0 shim coil array was designed as a tradeoff between shimming improvement and construction complexity, to provide an easy to use shim array that can be employed with the standard 7 T head coil. The array was interfaced using an open-source eight-channel shim amplifier rack. Improvements in field homogeneity for whole-brain and slice-based shimming were compared to standard second-order shimming, and to more complex higher order dynamic shimming and shim arrays with 32 and 48 channels.

Results
The eight-channel shim array provided 12% improvement in whole brain static shimming and provided 33% improvement when using slice-based shimming. With this, the eight-channel array performed similar to third-order dynamic shimming (without the need for higher order eddy current compensation). More complex shim arrays with 32 and 48 channels performed better, but require a dedicated RF coil.

Discussion
The designed eight-channel shim array provides a low-complexity and low-cost approach for improving B0 field shimming on an ultra-high field system. In both static and dynamic shimming, it provides improved B0 homogeneity over standard shimming.
Imagine How Good That Feels: The Impact of Anticipated Positive Emotions on Motivation for Reward Activities
Authors: Heise Max , Werthmann Jessica , Murphy Fionnuala , Tuschen-Caffier Brunna , Renner Fritz 
Published: May 2022

Abstract
Background
Disease burden and unsatisfactory treatment outcomes call for innovation in treatments of depression. Prospective mental imagery, i.e. future-directed voluntary imagery-based thought, about potentially-rewarding activities may offer a mechanistically-informed intervention that targets deficits in reward processing, a core clinical feature of depression. We propose that the previously described impact of prospective mental imagery on motivation for everyday activities is facilitated by affective forecasting, i.e. predictions about an individual’s emotional response to the imagined activities.

Methods
Participants (N = 120) self-nominated six activities to engage in over the following week and were randomized to either: (1) an affective forecasting imagery condition (n = 40); (2) a neutral process imagery condition (n = 40); or (3) a no-imagery control condition (n = 40).

Results
As predicted, increases in motivation ratings from pre to post experimental manipulation were significantly higher following affective forecasting imagery compared to both neutral process imagery (d = 0.62) and no-imagery (d = 0.91). Contrary to predictions, the number of activities participants engaged in did not differ between conditions.

Conclusions
Results provide initial evidence for a potentially important role of affective forecasting in prospective mental imagery. We discuss how these findings can inform future research aiming to harness prospective mental imagery’s potential for clinical applications.
A comprehensive study of code-removal patches in automated program repair
Authors: Ginelli Davide , Martinez Matias , Mariani Leonardo , Monperrus Martin 
Published: May 2022

AbstractAutomatic Program Repair (APR) techniques can promisingly help reduce the cost of debugging. Many relevant APR techniques follow the generate-and-validate approach, that is, the faulty program is iteratively modified with different change operators and then validated with a test suite until a plausible patch is generated. In particular, Kali is a generate-and-validate technique developed to investigate the possibility of generating plausible patches by only removing code. Former studies show that indeed Kali successfully addressed several faults. This paper addresses the single and particular case of code-removal patches in automated program repair. We investigate the reasons and the scenarios that make their creation possible, and the relationship with patches implemented by developers. Our study reveals that code-removal patches are often insufficient to fix bugs, and proposes a comprehensive taxonomy of code-removal patches that provides evidence of the problems that may affect test suites, opening new opportunities for researchers in the field of automatic program repair.