bluuebunny/crossref_metadata_2025_split huggingface dataset:
Juvenile systemische Sklerodermie
Authors: Foeldvari Ivan 
Published: November 2022

ZUSAMMENFASSUNGDie juvenile systemische Sklerodermie (jSSc) ist eine seltene Erkrankung mit teilweise schwerer Organbeteiligung. Eine frühe Erkennung der Organbeteiligungen ist wichtig, um Schäden zu verhindern. Die juvenile systemische Sklerodermie Inzeptionskohorte ist eine Kohorte von jSSc-Patienten und derzeit die größte Kohorte der Welt. In dieser Publikation werden die Charakteristika von 210 Patienten dargestellt, die aus der Datenbank bis 12/2021 extrahiert wurden. Es wird die aktuelle Erfassung der Organbeteiligung vorgestellt. jSSc-Patienten unterscheiden sich von Patienten, die im Erwachsenenalter erkranken. Die jSSc-Patienten mit diffusem Subset haben einen schwereren Verlauf.
It’s all about the sentential construction
Authors: Becker Israela 
Published: November 2022

Abstract
Cross-linguistically, very few complete sentences, as opposed to a myriad of phrases, lexicalize to become words.
I here offer an account for this skewed distribution, along the lines of Construction Grammar, by analyzing a set of mono-clausal
sentences in Hebrew which have indeed become – or are on the verge of becoming – words. I adopt the distinction between
categorical and thetic propositions, and show that only the latter can evolve into words. A thetic – unlike a categorical –
proposition, much like a verb-phrase, enables a tight semantic bonding between its components to form an ‘interpretatively
cohesive’ unit, which may lead to semantic change. An evaluative thetic – unlike a categorical – proposition is comment-like,
hence ‘semantically-incomplete’, and in need of a topic from prior discourse to predicate on, which may lead to a change in
grammatical status. All verb-phrases meet these two criteria but only few sentences do, hence, I argue, the skewed distribution of
sources from which new words evolve.
Predicted superconductivity and superionic state in the electride Li5N under high pressure
Authors: Wan Zhongyu , Zhang Chao , Yang Tianyi , Xu Wenjun , Zhang Ruiqin 
Published: November 2022

Abstract
Recently, electrides have received increasing attention due to their multifunctional properties as superconducting, catalytic, insulating, and electrode materials, with potential to offer other performance and possess novel physical states. This work uncovers that Li5N as an electride possess four novel physical states simultaneously: electride state, super-coordinated state, superconducting state, and superionic state. By obtaining high-pressure phase diagrams of the Li–N system at 150–350 GPa using a crystal structure search algorithm, we find that Li5N can remain stable as P6/mmm structure and has a 14-fold super-coordination number, as verified by Bader charge and electron localization function analysis. Its superconducting transition temperature reaches the highest at 150 GPa (T
c = 48.97 K). Besides, Li5N exhibits the superionic state at 3000 K, in which N atoms act like solid, while some Li atoms flow like liquid. The above results are further verified at a macroscopic level by using deep learning potential molecular dynamics simulations.
Water-related disasters in Comal watershed – Indonesia: typology and policy support
Authors: Nur M , Handayani W 
Published: November 2022

Abstract
Water-related disasters, such as floods and drought, continue to occur in the Comal Watershed area because of several reasons such as high growth of land conversion and insufficient policy support. Each type of disaster happens in a particular prone area that can be identified based on certain characteristics. Accordingly, this paper aims to identify the typology of the occurring disaster and subsequently assess the disaster risk reduction efforts that have been implemented by government institutions. Content analysis was applied to further explore the disaster phenomena in the area. Data obtained from various secondary data sources such as mass media and planning documents related to the selected basin. The results of the study show that catastrophic disasters take place in particular natural physical conditions of the river basin. Other than that, disaster risk reduction efforts have been conducted in accordance with the efforts of integrated water resources management.
Hydrogeomorphology of spring at the junction of sumbing-sindoro twin stratovolcanoes, central java
Authors: Ervin M , Anafi M A , Arif A , Puspita H R A , Dewi A N , Ashari A 
Published: November 2022

Abstract
The study on the potential of springs is urgently needed to support sustainable development in the stratovolcano area. This study was conducted in the junction of Sumbing and Sindoro stratovolcano, to analyze the characteristics of springs which include the pattern of distribution, discharge, and, water quality. The data were collected by employing observation, literature study, and documentation. The data analysed using GIS, statistical and descriptive analysis. The results show that springs patterns are random. The spring discharge in both volcanoes varies between class V to VI. Between the Sumbing and Sindoro there is no difference in the average of discharge, water temperature, DO, and pH, but it is different in the average of TDS and EC. Water temperature has a strong influence on EC in Sumbing but weak in Sindoro. The increase in water temperature has a weak effect on the decrease of DO in both volcanoes. The decrease in spring elevation influences the increase in water temperature, strong in Sumbing but weak in Sindoro. The difference in geomorphological conditions between Sumbing and Sindoro contributes to the variation of the spring’s characteristics. Overall, this paper presents new insights to understand the effect of different geomorphological conditions in two adjacent stratovolcanoes on the characteristics of springs.
Young Citizens’ Perceptions of Informal Green Space - A Study of Japanese High School Student's Place Attachment and Desire to Live in Rural Areas
Authors: Tanaka Yuri , Mao Yingming , Furuya Katsunori 
Published: November 2022

Abstract
One of the Sustainable Development Goals (SDGs) adopted at the UN Summit in September 2015 includes the greening movement, in which ordinary citizens can actively participate. Goals 3, 11, 13, and 15 of SDGs contribute to health and well-being, sustainable cities and communities, measures against climate change, and protection of life on land, respectively. In this context, studies of urban green spaces have been conducted on greening movements. Most studies have focused on formally recognized green spaces such as parks, gardens, and forests. “Informal green spaces” refer to small plots of land covered with greenery such as grassy areas on roadsides, vacant lots, and vegetation beside railroad tracks and waterways; however, they are considered separate from formal green spaces. A previous survey of informal green space usage in Ichikawa City, Chiba Prefecture, showed that residents were aware of informal green spaces in their neighborhoods and viewed them as potential auxiliary green spaces. However, the study mainly focused on the elderly, and no studies have focused on youth from junior high or high school as the primary research target. Therefore, this study aimed to clarify whether the results from previous studies were relevant to younger generations and a broader range of cities.
This study focuses on the cities near Ichikawa, located in the metropolitan area of Japan, urbanized with residential condominiums and other buildings. There are several formal green spaces, and interest in greenery is relatively high. We first surveyed the actual conditions of various informal green spaces in Chiba and recorded their location information and types. Based on the data obtained, a questionnaire on the use and evaluation of informal green spaces was designed, and the responses were collected using “Classi,” an ICT platform for students and teachers, from Ichikawa Gakuen’s students (junior high school to senior high school) and teachers.
Green spaces can help to build a sustainable society by improving physical and mental health through exposure to nature, developing cities where people can continue to live, and reducing heat islands. The importance of formal and informal green spaces in cities has been highlighted in this study, which indicated that informal green spaces not only enrich people’s lives but also have the potential for new usage. This study emphasizes that in urban areas with many restrictions, informal green spaces play a complementary role to formal green spaces.
Permaculture Landscape as an Adaptive Strategy towards Food Security at Community-Scale
Authors: Kurniawati I , Dahlan M Z , Faisal B 
Published: November 2022

Abstract
Food security still becomes a big challenge nowadays, especially since the spreading of Covid-19 pandemic. Facts show that a large-scale social restriction policy in Indonesia limits the movement of logistics to distribute food. This situation tends to worsen due to the limited number of agricultural lands. Environmental or ecological sustainability in agriculture activity is also rarely considered, making the land poor for agriculture. Permaculture can be a viable approach to achieve sustainable food security, by creating a cultivated ecosystem which provides necessary human needs along with natural regeneration. Kuttab Al Fatih (KAF) Islamic School was chosen as the case study because contextually KAF has the potential to implement permaculture to its landscape development. Therefore, this paper discusses how to implement permaculture to KAF landscape development. This research was conducted with a literature review, field survey, and case study to determine permaculture design considerations within the selected project. The findings show that the permaculture landscape encourages the people to serve their needs (including foods) within the site without harming the environment. Through mimicking nature and adapting the pattern, permaculture system can create a sustainable ecosystem for people and other creatures to live in harmony. The implementation of permaculture at KAF should consider the Islamic values and the prohibitions in order the implementation does not conflict with user’s beliefs. User’s food needs, procurement, and human resources become another factor that should be considered to ensure the permaculture implementation is visible at KAF since the users are not staying at school.
Managing Visitor Behaviour Using Border Elements to Avoid Covid-19 Spreading in Gajah Park, Bandar Lampung
Authors: Sitompul R A , Ricardo D , Franjaya E E 
Published: November 2022

Abstract
Gajah Park as a green open space and public space in Bandar Lampung has a socio-cultural function such as a communication medium and a recreation place for residents. To support this function, the existing condition of the Gajah Park has several available facilities such as; commercial area, talent training area, children’s playground and others. However, these facilities lack clear territorial boundaries so that the visitors who come to Gajah Park can move from one area to another freely. This condition also causes crowding in some areas and hard to maintain physical distancing, especially in the current Covid-19 pandemic situation. This research aims to evaluate the existing condition of the Gajah Park and to figure out the benefits of border elements as landscape elements to influence behaviour and limit the movement of visitors to maintain physical distancing. This research uses a descriptive qualitative method by collecting data fields and observations to determine the dimension of the site, behaviour setting, behaviour mapping, and the existing condition of border elements. The result of this study is the recommendation of border element’s design to apply in Gajah Park.
Fuzzy PID control method for damping of electronically controlled air suspension shock absorbers for vehicles
Authors: Zhang Peng , Chen WuWei , Wang Hongxin , Wang Junqi , Lu Huacai , Cheng Zhenbang 
Published: November 2022

Abstract
A damping fuzzy proportional-integral-derivative (PID) control method for electronically controlled air suspension shock absorbers was proposed to reduce the RMS values of the body vibration acceleration and improve vehicle ride comfort. Depending on the operating mode of the electronically controlled air suspension shock absorber, a mechanical model of the air suspension shock absorber was established. A fuzzy PID control technology for damping control of the shock absorber is designed by combining a PID control algorithm with the fuzzy control concept. The adaptive expansion factor of the cybernetics domain for the fuzzy PID controller is calculated by considering nonlinear characteristics and time delay to improve the controller’s adaptability. Then, the control parameters are adjusted based on the control deviation and deviation rate parameters. The nonlinear detection platform produced by an enterprise is selected to build an experimental environment for analysis. Simulation results reveal that when the vehicle speed is 30 km h−1, the RMS values of the body vibration acceleration upon applying the proposed method is approximately 0.02 and 0.05 km h−2, respectively, on Class B and C road surfaces. Furthermore, the RMS values of the body vibration acceleration using the proposed method has little fluctuation; when the vehicle speed is 60 km h−1, the RMS values of the body vibration acceleration is 0.022 and 0.028 km h−2, respectively, on Class B and C road surfaces, indicating that the proposed method can effectively reduce the RMS values of the body vibration acceleration and improve rider comfort.
How are Atlantic basin-wide hurricane activity and economic losses related?
Authors: Hemmati Mona , Camargo Suzana J , Sobel Adam H 
Published: November 2022

Abstract
The authors investigate the statistical relationships between interannual variations in economic losses from Tropical Cyclones (TCs), basin-wide metrics of TC activity, and indicators of large-scale climate variability in the North Atlantic basin. The results show substantial and statistically significant correlations between the economic losses and some seasonal TC activity metrics, namely the accumulated cyclone energy and power dissipation index. These results suggest that accurate seasonal forecasts of these metrics can be taken as relevant to potential TC losses, even though the metrics in question do not take into account whether storms make landfall, let alone where they do so. The authors suggest that the degree of correlation obtained might be considered a baseline against which to measure some aspects of the performance of catastrophe models.
Leucine-Rich Alpha-2 Glycoprotein Is a Reliable Serum Biomarker for Evaluating Clinical and Endoscopic Disease Activity in Inflammatory Bowel Disease
Authors: Shimoyama Takahiro , Yamamoto Takayuki , Yoshiyama Shigeyuki , Nishikawa Ryutaro , Umegae Satoru 
Published: November 2022

Abstract

Background
Leucine-rich alpha-2 glycoprotein (LRG) is a novel serum biomarker for inflammation in inflammatory bowel disease (IBD). This prospective study aimed to compare the value of LRG with C-reactive protein (CRP) and fecal calprotectin for evaluating clinical and endoscopic disease activity in patients with IBD.

Methods
At entry, clinical and endoscopic disease activity was assessed in 267 patients with IBD (ulcerative colitis [UC] 203; Crohn’s disease [CD] 64), and the levels of LRG, CRP and fecal calprotectin were measured. The accuracy of the biomarkers for the detection of clinical and endoscopic disease activity was determined by the area under the receiver operating characteristic curve.

Results
Leucine-rich alpha-2 glycoprotein showed a significant relationship with the clinical and endoscopic severity in both UC and CD (both diseases, P &lt; .0001). In the clinical assessment of UC, the accuracy of LRG was significantly higher than that of CRP (0.73 vs 0.63; P &lt; .001). In the endoscopic assessment of UC, the accuracy of LRG was significantly higher than that of CRP (P = .01), but it was significantly lower than that of fecal calprotectin (P = .009; LRG, 0.80; CRP, 0.72; fecal calprotectin, 0.91). In the clinical and endoscopic assessment of CD, the accuracy was not significantly different between the biomarkers (clinical activity: LRG, 0.71; CRP, 0.64; fecal calprotectin, 0.66; in endoscopic activity: LRG, 0.79; CRP, 0.78; fecal calprotectin, 0.81).

Conclusions
Leucine-rich alpha-2 glycoprotein is a reliable serum biomarker for the assessment of clinical and endoscopic disease activity in patients with IBD. It can be an alternative to CRP for the assessment of UC.
Rapid Quantitative Determination Control Male Sexual Dysfunction Drug Content of Sildenafil and Tramadol Mixture by Spectrophotometry Along With Smart Chemometrics Approaches Compared to the HPLC Reference Method
Authors: Ramin Mehdi , Sohrabi Mahmoud Reza , Motiee Fereshteh 
Published: November 2022

Abstract

Background
There are reports for the simultaneous estimation of sildenafil (SIL) and tramadol (TM) using chromatographic techniques. Some limitations of these methods are high cost and time, more usage of pollutant solvents, and complicated instruments.

Objective
Simultaneous determination of SIL and TM in the anti–sexual dysfunction pharmaceutical formulation using rapid and smart chemometrics approaches along with spectrophotometry.

Method
In this study, a spectrophotometric analysis method based on continuous wavelet transform (CWT), partial least-squares (PLS), and radial basis function neural network (RBF-NN) was presented.

Results
In the CWT method, the Symlet (Sym2) and Daubechies (db2) wavelet families with wavelengths of 268 and 221 nm were considered the best families for SIL and TM, respectively. The limit of detection (LOD) and limit of quantitation (LOQ) values were found to be 0.0185, 0.0054 μg/mL and 0.0458, 0.3092 μg/mL for SIL and TM, respectively. The mean recovery values were 101.06 and 101.49% for SIL and TM, respectively. The results of PLS revealed that the root-mean-square error (RMSE) of SIL and TM was 0.0286 and 0.0635, respectively. Also, the mean recovery of both drugs was obtained over 99%. The mean square error (MSE) of RBF-NN was 5.88 × 10−29 and 4.61 × 10−27 for SIL and TM, respectively.

Conclusions
A statistical comparative study conducted for the proposed methods with the high-performance liquid chromatography (HPLC) technique demonstrated no significant difference between these methods. The suggested approaches were simple, fast, accurate, and affordable.

Highlights
Three smart UV spectrophotometric methods based on chemometrics were presented to determine SIL and TM simultaneously. The efficient chemometrics methods, including CWT, PLS, and RBF-NN, were used. The mentioned methods are rapid, simple, inexpensive, and accurate. The comparison was performed between the proposed models and HPLC technique.
Overview of Analytical Methods for Evaluating Tinidazole
Authors: Pereira Sousa Jean Carlos , Kogawa Ana Carolina 
Published: November 2022

AbstractBackgroundTinidazole (TIN) has amoebicidal, giardicidal, antifungal, and antimicrobial activities. It is marketed in the form of tablets. Analytical methods to assess the quality of TIN-based products are essential for correct pharmacotherapy.ObjectiveThe objective of this review is to show an overview of the existing analytical methods for evaluating TIN, according to the quality control (QC) analysis routine and green analytical chemistry (GAC).ResultsOfficial compendia show a method for evaluating TIN in tablets by nonaqueous titration, which has limitations (materials on the mg scale using solvents considered not recommended and harmful). The literature shows some analytical methods for evaluating TIN, both physicochemical and microbiological. The most used physicochemical method is UV (41%), and second is HPLC (28%). Among the microbiological methods, agar diffusion and turbidimetric methods are equally divided. The most studied matrix is TIN tablets (73%), and the most used solvent is methanol.ConclusionsThe literature shows space for the development of analytical methods according to GAC for evaluating TIN, optimizing time, resources, and materials, reducing waste generation, and opting for less aggressive reagents, solvents, and diluents.HighlightsThis review shows the status of analytical methods, both physicochemical and microbiological, for the analysis of TIN in pharmaceutical matrix, in the context of routine analysis of the chemical-pharmaceutical industries and of GAC.
Gas coal delamination recognition method based on the Fisher discriminant function of trace element characteristics
Authors: Pan Hui , Zhou Wei , Chen Dezhong , Zhang Hongling , Han Yunchun 
Published: November 2022

Abstract
Numerous geological factors will affect determining the well bottom position by well depth during the construction of coalbed methane wells, resulting in inaccurate results. By using the trace element characteristics of coal samples to determine the source layer of coal samples, it is possible to avoid making incorrect assumptions. The groove method was used in this study to collect 40 gas coal samples from seven gas coal seams in Dingji Mine, which were then sealed and stored. The contents of 40 different trace elements were analyzed in the samples, and the types and content characteristics of trace elements in each coal seam were determined preliminarily through content distribution map analysis. Simultaneously, the SPSS analysis software was used to analyze the 1600 trace element test data from various coal seams, and cluster analysis was performed using the average link method between classes. The clustering tree diagram was created, and the discrimination was calculated using the distance between classes and samples. This study analyzed the typical explanatory variables and established the Fisher discriminant function for coal seam identification. Accordingly, identifying gas coal stratification requires only measuring the concentrations of nine trace elements (typical explanatory variables) in the coal seam being discriminated against. This method can be used in Dingji mine to determine the final hole horizon of surface coalbed methane wells and eliminates the risk of accidentally exposing coal seams during the excavation of an underground roadway.
A ‘wiring diagram’ for sink strength traits impacting wheat yield potential
Authors: Slafer Gustavo A , Foulkes M John , Reynolds Matthew P , Murchie Erik H , Carmo-Silva Elizabete , Flavell Richard , Gwyn Jeff , Sawkins Mark , Griffiths Simon 
Published: November 2022

AbstractIdentifying traits for improving sink strength is a bottleneck to increasing wheat yield. The interacting processes determining sink strength and yield potential are reviewed and visualized in a set of ‘wiring diagrams’, covering critical phases of development (and summarizing known underlying genetics). Using this framework, we reviewed and assembled the main traits determining sink strength and identified research gaps and potential hypotheses to be tested for achieving gains in sink strength. In pre-anthesis, grain number could be increased through: (i) enhanced spike growth associated with optimized floret development and/or a reduction in specific stem–internode lengths and (ii) improved fruiting efficiency through an accelerated rate of floret development, improved partitioning between spikes, or optimized spike cytokinin levels. In post-anthesis, grain, sink strength could be augmented through manipulation of grain size potential via ovary size and/or endosperm cell division and expansion. Prospects for improving spike vascular architecture to support all rapidly growing florets, enabling the improved flow of assimilate, are also discussed. Finally, we considered the prospects for enhancing grain weight realization in relation to genetic variation in stay-green traits as well as stem carbohydrate remobilization. The wiring diagrams provide a potential workspace for breeders and crop scientists to achieve yield gains in wheat and other field crops.