bluuebunny/crossref_metadata_2025_split huggingface dataset:
Jump-Landing Mechanics Assessment Using Landing Error Scoring System in Athletes with and without Patellofemoral Pain:
Authors: Rabanni Majid , Esfandiarpour Fateme , Saadat Maryam , Jahangiri Mina 
Published: December 2022

Abstract
Purpose: This study was a cross-sectional study that aimed to compare the total LESS scores of individuals with PFP with healthy controls and assess the association of pain, function, and psychological factors with LESS score.
Methods: Twenty-seven male athletes with PFP completed a standardized jump-landing task. They were compared with a matched, healthy group. Also, participants completed four questionnaires involving the visual analog scale (VAS), Anterior knee pain scale (AKPS), fear of motion (TAMPA), beck anxiety and depression inventory scale (BAI, BDI).
Results: PFP group had a higher total LESS score than the control group significantly. They had errors when landing with lateral trunk flexion and less knee flexion in the initial contact. Our results showed a significantly strong correlation between VAS, AKPS, and TAMPA with a final score LESS. Also, a low to moderate significant correlation obtained between BAI, BDI and final score LESS.
Conclusions: The LESS is a useful clinical test for evaluating landing errors in people with PFP. Greater kinesiophobia, pain, poorer self-reported function and psychological factors was correlated with a total LESS score.
Microtextural signatures in quartz grains and foraminifera from tsunami deposits of the Portuguese shelf
Authors: Yhasnara Missilene , Costa Pedro JM , Dourado Francisco , Martins Maria Virginia Alves , Feist Lisa , Bellanova Piero , Reicherter Klaus 
Published: December 2022

Abstract

This study presents results from two sediment cores collected on the southern Portuguese shelf attempting to, partially, fill the knowledge gap of the offshore record of high-energy events. The results were obtained based on description of cores, microtextural analysis of quartz grains and foraminiferal taphonomy. The lithostratigraphy, corresponding to late Holocene sedimentation, with intercalations of medium sand-rich in bioclastic fragments with erosive basal contact. In terms of microtextures, a high degree of mechanical marks on the grains associated with tsunami deposition was observed and reflects the high-energy hydrodynamic processes. In compositional terms the higher presence of quartz grains in these units favours the increase of mechanical marks, because grain-to-grain contact is more intense. Additionally, the geomorphological setting of the coring sites determined the degree and type of mechanical microtextures observed. Furthermore, post-depositional changes and characteristics of the original sediment source contribute to explain the occurrence of dissolution in units of GeoB23513-02. The foraminiferal taphonomy displayed a predominance of dissolution alteration in the tests surfaces that was more evident in the silty layers. On the other hand, similarly to quartz grains microtextural signature, the sandy high-energy units exhibit a slight predominance of physical processes despite the still strong presence of dissolution. Furthermore, the sole presence of species (middle to outer shelf) in some units is an indication that there was little reworking of these specimens. Finally, the results obtained in this study show potential to recognize the microtextural signature of Holocene tsunami events in offshore environments.
Overexpression of SHCBP1 predicts poor prognosis of gastric cancer
Authors: Du Hua , Zhang Haifeng , Sun Wei , Hai Lin , Xu Xiaoyan , Wen Lixin , Shi Yingxu , Liu Honggang 
Published: December 2022

Abstract
Background
SHC SH2-domain binding protein 1 (SHCBP1) functions as an oncogene in different cancers. The effect pattern of SHCBP1 in gastric cancer (GC) tissues and the relationships between SHCBP1 expression and GC progression were explored in our study.
Methods
The expression of SHCBP1 in GC tissues and corresponding adjacent tissues was analyzed by immune histochemistry, Western blot and RT-PCR. With bioinformatics methods, the associations between the expression level of SHCBP1 and different cancer progression were also analyzed. In addition, the knockdown of SHCBP1 gene using shRNA transfection was applied to investigate the effect of SHCBP1 expressionon the proliferation, migration, invasion and epithelial to mesenchymal transition (EMT) capabilities of GC cells.
Results
The expression level of SHCBP1 mRNA was significantly increased in GC tissues compared with that of the adjacent tissues (P < 0.05). The expressions of SHCBP1 in GC tissues were associated with T stage and TNM stage. High SHCBP1 expression and TNM stage were independent factors to predict poor prognosis for GC patients.With the bioinformatics database, SHCBP1 could be treated as an oncogene of GC. And the in vitro study further confirmed that the knockdown of SHCBP1 expression in GC cells effectively suppressed the proliferation, migration, invasion and EMT capabilities of GC cells.
Conclusions
Our results indicate that SHCBP1 promote the metastasis of GC and could be served as potential prognostic marker and potential molecular target for GC therapy.
Sex and gender differences in treatment intention, quality of life and performance status in the first 100 patients with periampullary cancer enrolled in the CHAMP study
Authors: Hau Sofie Olsson , Williamsson Caroline , Andersson Bodil , Eberhard Jakob , Jirström Karin 
Published: December 2022

Abstract
Background
Periampullary cancer is a term for cancers arising in or in close proximity to the pancreas. Pancreatic cancer is the 3rd leading cause of cancer death for both sexes and while surgery is the only option for cure, chemotherapy is given in both the adjuvant and palliative settings. The aim of this study was to investigate any sex and gender differences in patients with pancreatic and other periampullary adenocarcinomas enrolled in a prospective, observational trial.
Methods
The study cohort consists of the first 100 patients, 49 women and 51 men, enrolled in the Chemotherapy, Host Response and Molecular dynamics in Periampullary cancer (CHAMP) study, an ongoing study of patients undergoing neoadjuvant, adjuvant or first-line palliative chemotherapy treatment. Twenty-five patients had surgery with curative intent and subsequent adjuvant treatment, and 75 patients were treated with palliative chemotherapy. Data regarding health-related quality of life (HRQoL, EORTC-QLQ-C30) at baseline, demographic and clinicopathological factors were examined and stratification by treatment intention according to sex. Overall survival (OS) was calculated through Kaplan-Meier analysis.
Results
There was a statistically significant difference between male and female patients treated with curative intent, with fewer women having undergone surgery (18 vs 7, p = 0.017), also after adjustment for age, tumor location and performance status. No statistical differences were found between the sexes regarding age, comorbidities, or clinicopathological factors. Before start of chemotherapy treatment, health-related quality of life (HRQoL) was lower in female than in male patients. However, HRQoL was not associated with performance status in female patients, whereas in male patients several HRQoL indicators were significantly positively associated with poorer performance status at baseline.
Conclusions
This study shows no clear differences between the sexes regarding biological factors concluding that gender bias might be responsible for the discrepancy between men and women being offered curative surgery. The observed difference between women and men regarding the association between HRQoL and performance status is unprecedented. Altogether these findings underline the importance of taking gender into consideration when assessing eligibility for curative surgery in order to improve biological outcome and decrease suffering in both sexes.
Study on the fretting wear evolution model of wires with curvature inside metal rubber
Authors: li hongyin , Ren Zhiying , Shen Liangliang , Huang Jianmeng , Shi Linwei 
Published: December 2022

Abstract
Metal rubber (MR) is a damping material with a space-disordered network interpenetrating structure. The fretting wear and fracture of its internal spiral turn caused by mutual extrusion and friction are the main reasons for its fatigue failure. However, the research on fretting wear of metal wire with curvature inside metal rubber is rarely reported, and the influence of curvature on the fretting wear of spiral metal wire is unclear. In order to deeply explore the fretting wear characteristics of metal wires with curvature, the fretting wear evolution model of metal wires with curvature was deduced and constructed in this work. Combined with finite element simulation and tribological test, the difference of fretting wear between metal wire with curvature and metal wire without curvature was analyzed. The results show that the fretting wear model of metal wire with curvature can accurately predict the wear degree of metal wire with curvature. The prediction accuracy error is within 10% under all working conditions. There are apparent differences between the metal wire with curvature and the metal wire without curvature under the same working conditions. In particular, when the metal wire contacts at a slight angle, the difference in the wear degree between them is extensive, and the error decreases with the increase of contact angle. The fretting wear evolution model of metal wire with curvature is more suitable for predicting fretting wear of metal wire contact pairs, which abound in MR in the form of low contact angle and high curvature.
Physicochemical Characteristics of Shrimp Ponds on Mangrove Ecosystems in Kannur District of Kerala, India
Authors: Krishnapriya P , Bijith P , Sandeep S 
Published: December 2022

Abstract
Mangrove forests are one of the most productive ecosystems in the world and are known for their ecological, economic, and social importance. Large-scale shrimp farming severely threatens mangrove ecosystems since shrimp productivity is correlated with mangrove ecosystems. The present study was carried out to determine the physicochemical characteristics of soil and water of traditional and non-traditional shrimp ponds near mangroves for understating the variation from the natural mangrove ecosystems of the Kannur district. Different parameters such as pH, electrical conductivity, BOD, DO, alkalinity, acidity, fluoride, iron, sulphate, nitrate, calcium, magnesium, and total hardness of collected water sample and pH, electrical conductivity, nitrogen, phosphorus, potassium, organic carbon and heavy metal contents of collected soil samples were determined by respective instruments and methods. From the analysis, it was found that all the parameters of traditional, as well as non-traditional shrimp ponds showed significant variation from the natural mangrove ecosystems. The result from the statistical analysis, t-test, concluded that the parameters of water such as pH, temperature, alkalinity, dissolved oxygen (DO), biological oxygen demand (BOD), fluoride, nitrate, and iron contents of traditional shrimp ponds, and pH, BOD, nitrate, sulphate and total hardness of non-traditional shrimp ponds significantly varied from its corresponding natural mangrove ecosystems. In addition, the phosphorus content in soil samples from traditional shrimp ponds and the pH, electrical conductivity, phosphorus, potassium, lead, and chromium in soil from non-traditional shrimp ponds significantly varied from corresponding natural mangroves. Changes in those physicochemical parameters of soil and water will affect the associated organisms and restrict further restoration of mangroves in the long term.
Tick-borne pathogens of cattle in smallholder rural livestock production systems in East and West Africa
Authors: Heylen Dieter J.A. , Kumsa Bersissa , Kimbita Elikira , Frank Mwiine Nobert , Muhanguzi Dennis , Jongejan Frans , Adehan Safiou Bienvenu , Touré Alassane , Aboagye-Antwi Fred , Ogo Ndudim Isaac , Juleff Nick , Crafford Dionne , Fourie Josephus , Labuchange Michel , Madder Maxime 
Published: December 2022

AbstractBackground:The majority of the African population lives in rural areas where they heavily depend on crop and livestock production for their livelihoods. Given their socio-economic importance, we initiated a standardized multi-country (Benin, Burkina Faso, Ghana, Nigeria, Ethiopia Tanzania and Uganda) surveillance study to assess the current status of important tick-borne haemoparasites (TBHPs) of cattle across these seven sub-Saharan African territories.Methods:We assessed vector-borne pathogen prevalences (Anaplasma marginale, Anaplasma centrale, Babesia bigemina, Babesia bovis, Ehrlichia ruminantium, andTheileria parva) in the blood of cattle, via molecular screenings in approximately 480 individuals per district in two districts per country and seven countries each. In addition, we screened for intrinsic (sex, weight, body condition) and extrinsic (husbandry, tick exposure) risk factors as predictors of infections with TBHPs.Results:There was a large macro-geographic variation observed inA. marginale, B. bigemina, B. bovis, E. ruminantiumprevalences. Most correlated with the co-occurrence of their specific sets of vector-competent ticks. Highest numbers of infected cattle were found in Benin, and lowest in Burkina Faso. WhileT. parvawas seldomly found in the cattle blood (Uganda only: 3.0 %),A. marginalewas found in each country with a prevalence of at least 40 %. Lower body condition score was found inB. bovisinfected cattle. Age (as estimated via the cattle’s body weight) of the animal was higher inA. marginaleinfected cattle, but was negatively correlated withB. bigeminaandE. ruminantiumprevalence.Ehrlichia ruminantiuminfection was more often found in males, andA. marginalemore often in transhumance farming. High levels of co-infection, especially the combinationA. marginalexB. bigemina, were observed in all countries, except for Uganda and Burkina Faso.Babesiabigeminawas more or less often observed than expected by chance, when cattle were also co-infected withE. ruminantiumorA. marginale, respectively.Conclusions:Tick-borne pathogens of cattle, including the highly virulentB. bovisandE. ruminantium,are ubiquitous in smallholder cattle production systems in Africa. This study is the first in its kind to demonstrate the negative impact ofB. bovison body condition score, a proxy for production. Looking at the continuous spread of its major vectorR. microplus, this finding is of major importance to cattle production in many parts of the world whereR. microplusis prevailing. Our study will help a wide range of stakeholders to provide recommendations for TBHP surveillance and prevention in cattle.
Robot-assisted Laparoscopic Adenomyomectomy
Authors: Usta Taner , Yilmaz Salih , Ozkaynak Aysel , Ceylan Gizem Nil , Kale Ahmet , Oral Engin 
Published: December 2022

Abstract
Adenomyosis is a benign uterine disorder where endometrial gland and stromal tissue are abnormally located within the myometrium. The common symptoms of adenomyosis are abnormal uterine bleeding (menorrhagia), dysmenorrhea, dyspareunia and infertility.
The gold-standard method for treating adenomyosis is hysterectomy. For patients who desire to preserve their uterus, an alternative therapy would be adenomyomectomy which is sparing uterus. Such a procedure may be performed with open surgery or minimally invasive surgery.
It is obvious that minimal invasive surgery would be better for the patient’s health. However, there is inadequate evidence to decidedly say which invasive surgery which invasive surgery would be best for the patient. We suggest that one of the newest techniques, robotic surgery is to be preferred an alternative approach for gynecological operations as well as would be an option for uterine surgery. This technique would allow for 3-D visualization and multijoint endowrist movement, which compared to laparoscopy, yields various advantages for surgeons.
We therefore recruit seven participants diagnosed with symptomatic adenomyosis who admitted to Endometriosis and Chronic Pelvic Pain Center of Acibadem Altunizade Hospital between March 2019and January 2021 requested to preserve fertility. They all underwent robotic adenomyomectomy. The parameters evaluated herein will be, whether the pain and bleeding scores changed during the postoperative period, amount of blood loss during the operation and the associated decrease in Hg levels. Robotic adenomyomectomy is one of the uterus-sparing adenomyosis surgery methods and is safely applied in selected patients.
Utilization of Triple Antithrombotic Therapy in Patients with Atrial Fibrillation Undergoing Percutaneous Coronary Intervention
Authors: Choi Hye-Jeong , Lee Yonghyuk , Park Susin , Je Nam Kyung 
Published: December 2022

Abstract
Background:
Triple antithrombotic therapy (TAT), a combination of an oral anticoagulant and dual antiplatelet agents (DAPT), is a key treatment for prevention of ischemic events in patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI). However, TAT is not extensively used because of the risk of bleeding.
This study aimed to determine the utilization and influencing factors of TAT using real-world data in the non-vitamin K antagonist oral anticoagulants (NOACs) era.
Methods:
We analyzed National Inpatient Sample data compiled by the Health Insurance Review & Assessment Service (HIRA-NIS) from 2011 to 2020. Patients with AF who underwent PCI with stent implantation and with an increased stroke risk, were selected as candidates for TAT therapy. Demographic and clinical factors associated with TAT use were investigated using the chi-squared test and the student's t-test, and influencing factors were identified using multiple logistic regression.
Results:
The TAT utilization rate steadily increased from 30.3% in 2011 to 65.4% in 2020 (Cochran-Armitage trend test: p < 0.001) with an average of 45.9%. Positive influencing factors for TAT use were identified as congestive heart failure, history of previous stroke/transient ischemic attack/thromboembolism, valvular heart disease, and year. Negative influencing factors included insurance type (medical aid or Patriots & Veterans Insurance), type of medical institution (general hospitals or primary medical institutions), and comorbidities such as renal disease, liver disease, and history of the previous hemorrhage.
Conclusions:
In patients with AF with an increased stroke risk, TAT utilization after PCI increased progressively from 2011 to 2020, reaching 65.4% by 2020. However, in 2020, 29.4% of patients were still prescribed DAPT, suggesting that many AF patients undergoing PCI did not receive adequate antithrombotic therapy even in the NOACs era. This trend was more pronounced in patients at high risk of bleeding.
Fabrication and functionality of 3D-printed porous scaffolds composing natural derivatives of duck bones and fish shells and poly(ε-caprolactone)
Authors: Wu Dung-Yi , Shih Wen-Ling , Wang Chin-San , Wu Chin-San 
Published: December 2022

Abstract

Recycled duck bones (DBs) and fish shells were processed into natural derivatives. Through innovative design, these natural derivatives were then combined with biopolymers to create a new type of ecofriendly filament suitable for three-dimensional (3D) printing of scaffolds for bone regeneration. The DBs and fish shells were thermally processed to produce DB-derived hydroxyapatite (HA) and fish shell-derived Ca(OH)2 (TAS), respectively. Poly(ε-caprolactone) (PCL), HA, and TAS were combined and fabricated into new composite filaments, which were then transformed into scaffolds using 3D printing technology. The structure and antibacterial behaviors of the obtained composite scaffolds were studied. Alone, PCL showed no bacterial inhibition. MHA (a mix of HA and TAS) was added to PCL to form a PCL/MHA composite material, which significantly improved the functional properties of PCL and enhanced cell attachment and proliferation. The Ca(OH)2 content of TAS was responsible for the antibacterial effect. The PCL/MHA composites were porous and displayed enhanced osteoblast proliferation in vitro. The osteoblast cell population do not affected when cultured on the PCL/HA and PCL/MHA series composites according to cell cycle distribution analysis. The surfaces of the various PCL/HA and PCL/MHA composites showed elevated levels of calcium and phosphorus compounds when exposed to simulated body fluids. Calcium and phosphate ions were rapidly deposited on PCL/HA and PCL/MHA composite scaffolds in osteoblasts according to the cell mineralization assay. Our findings suggest great potential of the PCL/HA and PCL/MHA composite scaffolds in bone tissue engineering applications.
Four-Way Classification of Alzheimer's Disease using Deep Siamese Convolutional Neural Network with Triplet-Loss Function
Authors: Hajamohideen Faizal , Shaffi Noushath , Mahmud Mufti , Subramanian Karthikeyan , Al-Sariri Arwa , Vimbi Viswan , Abdesselam Abdelhamid 
Published: December 2022

Abstract
Alzheimer's disease (AD) is a neurodegenerative disease that causes irreversible damage to several brain regions, including the hippocampus causing impairment in cognition, function, and behaviour. Early diagnosis of the disease will reduce the suffering of the patients and their family members. Towards this aim, in this paper, we propose a Siamese Convolutional Neural Network (CNN) architecture that employs the triplet-loss function for the representation of input MRI images as k-dimensional embeddings. We used both pre-trained and non-pre-trained CNNs to transform images into the embedding space. These embeddings are subsequently used for the 4-way classification of Alzheimer's Disease. The model efficacy was tested using the ADNI and OASIS datasets which produced an accuracy of 91.83% and 93.85%, respectively. Furthermore, obtained results are compared with similar methods proposed in the literature.