bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social media aesthetics as part of academic library merchandising
Authors: Wójcik Magdalena 
Published: December 2022

PurposeThe subject of this paper is the phenomenon of social media aesthetics, which can be perceived as a tool for promoting and building the image of libraries, especially in terms of merchandising. The aim of this paper is to analyse the potential of the dark academia social media trend in the promotion of academic libraries.Design/methodology/approachThe article is based on a review of the social networking sites YouTube and Instagram and an analysis of network resources using the Brand24 tool.FindingsResources that are described by Internet users as “dark academia” are popular in social media. Dark academia as an aesthetic concept creates potential for the promotion of academic libraries, especially those that are more traditional in terms of their architecture, décor or how they offer their services.Research limitations/implicationsThe paper concerns a phenomenon which, although popular socially, has not yet been scientifically analysed in the literature on the subject. Since the topic is new and there is no scientific literature on it, the author had to base the paper on less standard sources of information (e.g. analysis of the content of social media). The article is a review, an introduction, as well as an invitation to further discussion. The author's aim is not to comprehensively cover this topic but only to draw attention to an interesting and rarely discussed issue that has great potential for practical activities.Practical implicationsThe topic has great potential for the practical improvement of the promotional activities of libraries, especially older, more traditional libraries, to create a strong and positive image on the basis of characteristics often perceived as weaknesses.Social implicationsSocial media services are powerful social impact tools. Showing the potential role of social media aesthetics for cultural institutions could serve to make the public more aware of the role of the proper use of social media for promotion and image building.Originality/valueThe use of social media aesthetics is very rarely discussed in the subject literature.
Analyzing walkability in the vicinity of three metro stations in Doha, Qatar
Authors: Salaheldin Hadeel T. , Major Mark David , Ahmad Ahmad Mohammed , Tannous Heba O. 
Published: December 2022

PurposeMany factors contribute to public rail transit use in an urban network. However, a dysfunctional relationship between the built environment and the transport system significantly deters such use. Architects, urban designers, town planners and policymakers must understand the factors that promote or deter pedestrian use of the urban environment.Design/methodology/approachThe paper investigates four connectivity and walkability factors for three different metro stations in Doha, Qatar: Al Aziziyah, Hamad Hospital and West Bay. The analysis includes pedestrian sheds, block sizes, ground-level land uses and connectedness in the urban spatial network based on catchment contour maps using space syntax.FindingsThe results indicate the three metro stations and neighborhoods are representative of diverse type of neighborhoods in Doha: relatively compact but expansive for the Hamad Hospital Station area, metrically and topologically restrictive due to the poor planning and the peninsular location of the reclaimed land in the West Bay area, and expansive, shallow and reliant on attraction for the Al Waab transportation corridor associated with Al Aziziyah Station.Research limitations/implicationsTime factors and temporary closure/capacity reductions due to the global pandemic restricted planned efforts to collect more pedestrian use data based on passive observations and preference choices using surveys during the study. Nonetheless, adapting the investigation to the circumstances produced significant findings.Social implicationsThe analysis can help us develop better guidelines and diagnostic tools to calibrate design and planning strategies promoting more walkable, healthy and sustainable neighborhoods.Originality/valueThe study is original due to examining stations of the new Doha Metro for the first time. However, it relies on well-established representational techniques in urban morphology and space syntax research.
The path from customer experience to customer citizenship: new adventure is a touristic railway journey
Authors: Samsa Çağlar 
Published: December 2022

PurposeIn this study, the author aimed to measure the effect of customer loyalty on customer citizenship behavior as well as the effect of experience value perceptions of tourist railway journey customers on customer loyalty within the scope of social exchange theory.Design/methodology/approachThe author obtained data from 126 participants who had experienced the tourist railway adventure through random sampling. In the next stage, the author extracted the data obtained with the bootstrapping sample technique to 5,000 samples. The author analyzed these obtained data with the PLS-SEM model with the Smart PLS 3 software.FindingsThe results of the research show that the most important experience value dimension that creates loyalty in the touristic railway journey is the emotional value dimension; the second important dimension is the hedonic value dimension and other experience value dimensions did not have any effect on customer loyalty intention levels. In addition, an important result of the study is that loyal customers mostly intend to advise other customers, and relatively less of them intend to give feedback to the firm.Research limitations/implicationsThe fact that the concepts of touristic railway journeys are different due to the nature of tourism is an important limitation of the study, which is only for individuals who have experienced the Touristic Eastern Express. The fact that the Touristic Eastern Express is a long journey and stops at many destinations on its arrival and departure route can affect customers' perceptions of the experience value.Practical implicationsThe values that create customer loyalty in the touristic railway journey are mostly emotional and hedonic values. In addition, customers who are loyal as a result of this journey are more intent on advising other customers than giving feedback to the firm.Originality/valueThe study was carried out on the customers of the touristic eastern express, which started its activities in 2019. Ensuring customer loyalty for the sustainability of this trend has significant tourism potential; Afterwards, the transformation of customer loyalty into customer citizenship has a very important place. In addition, as far as we have examined the literature, the absence of similar studies in the tourism sector is an indicator of the study's originality. Considering these data, it is expected that the study will fill an important gap in terms of both sectoral and academic.
Modelling pollinator and nonpollinator selection on flower colour variation
Authors: Tenhumberg Brigitte , Dellinger Agnes S. , Smith Stacey D. 
Published: December 2022

AbstractFlower colour variation is ubiquitous within and between populations, which is why it has long been a focal point for studies of natural selection. This body of work has uncovered a wide range of selective agents, including pollinators, herbivores and various abiotic factors. Nevertheless, we lack an integrative framework for predicting the phenotypic outcome in terms of floral pigmentation when these forces act collectively and often in opposition.We here present such a framework through a model that incorporates selection on pigmentation at the vegetative phase (i.e. through survival to reproduction) and at the flowering phase (i.e. on pollinator attraction). We focus on anthocyanins as common class of pigments although the model is equally applicable to any compounds that can be jointly expressed in vegetative tissue and in flowers. We explore the dynamics of our model in a theoretical context and in four scenarios based on classic systems for studying selection on flower colour.Our model predicts that pollinators are the main driver for flower colour evolution, but selection on seedling survival plays a major role in the absence of pollen limitation, that is, if pollinator abundance is sufficiently high, or if pollinator preference is absent or weak (high variance in colour preference). In each of the case studies, our model recovered the predicted patterns of fitness for each floral morph given the strength and nature of selection.This work suggests that selection at the vegetative phase must act alone or be exceptionally strong to negate pollinator preference for particular colours. Nevertheless, the influence of differential survival associated with anthocyanin production leaves a clear signature on the fitness curves, suggesting that nonpollinator agents of selection can often be detected from empirical data.Synthesis: Overall, the application of this model to empirical systems will be key for understanding how flower colour diversity evolves and for predicting how changes in climate and pollinator communities may jointly alter evolutionary trajectories.
High co‐expression of SLC7A11 and GPX4 as a predictor of platinum resistance and poor prognosis in patients with epithelial ovarian cancer
Authors: Wu Xiaodong , Shen Shizhen , Qin Jiale , Fei Weidong , Fan Fengyun , Gu Jiaxin , Shen Tao , Zhang Tao , Cheng Xiaodong 
Published: December 2022

AbstractObjectiveThe aim was to assess the expression levels of SLC7A11 and GPX4 in relation to platinum resistance and prognosis in patients with epithelial ovarian cancer (EOC).DesignA retrospective cohort study.SettingWomen's Hospital, Zhejiang University School of Medicine, Hangzhou, China.Population or SampleWe included 192 eligible patients from hospital between January 2002 and December 2018.MethodsWe retrospectively analysed the medical records of patients with EOC. Surgical specimens of EOC were stained for SLC7A11 and GPX4. Survival analysis was performed using the Kaplan–Meier and Cox regression methods.Main Outcome MeasuresClinical end points include platinum‐free interval (PFI), progression‐free survival (PFS) and overall survival (OS).ResultsPatients with high co‐expression levels of SLC7A11 and GPX4 had a 60‐fold higher risk of platinum resistance compared with those with low co‐expression (risk ratio, 60.46; 95% confidence interval [CI] 22.76–160.58; p < 0.001). Moreover, high co‐expression level of SLC7A11 and GPX4 was an independent prognostic factor for poor OS (p < 0.001, hazard ratio [HR] 4.44, 95% CI, 2.77–7.14) and poor PFS (p < 0.001, HR = 5.73, 95% CI, 3.86–8.73). For in vitro experiments, SLC7A11 and GPX4 expression were both upregulated in platinum‐resistant cells compared with their parental ovarian cancer cells, and siRNA‐induced SLC7A11 and GPX4 inhibition decreased platinum resistance.ConclusionsHigh expression levels of SLC7A11 and GPX4 are associated with platinum resistance in EOC patients. High co‐expression of SLC7A11 and GPX4 may be a significant independent prognostic factor and a potential therapeutic target for platinum resistance in EOC patients.
Sustainability issues along the coffee chain: From the field to the cup
Authors: Barreto Peixoto Juliana A. , Silva Joana F. , Oliveira M. Beatriz P. P. , Alves Rita C. 
Published: December 2022

AbstractThe coffee industry is one of the most important commercial value chains worldwide. Nonetheless, it is also associated to several social, economic, and environmental concerns that impair its sustainability. The present review is focused on these main sustainability concerns from the field to the coffee cup, as well as on the strategies that are being developed and/or implemented to attain sustainability and circular economy principles in the different chain segments. In this context, distinct approaches have been applied, such as sustainable certifications (e.g., voluntary sustainability standards), corporate sustainability initiatives, direct trade, relationship coffee concepts, geographical indication, legislations, waste management, and byproducts valorization, among others. These strategies are addressed and discussed throughout this review, as well as their recognized advantages and limitations. Overall, there is still a long way to go to attain the much‐desired sustainability in the coffee chain, being essential to join the efforts of all actors and entities directly or indirectly involved, namely, producers, retailers, roasters, governments, educational institutions (such as universities and scientific research institutes), and organizations.
Navigating the seven challenges of taxonomic reference databases in metabarcoding analyses
Authors: Keck François , Couton Marjorie , Altermatt Florian 
Published: December 2022

AbstractAssessment of biodiversity using metabarcoding data, such as from bulk or environmental DNA sampling, is becoming increasingly relevant in ecology, biodiversity sciences and monitoring. Thereby, the taxonomic identification of species from their DNA sequences relies strongly on reference databases that link genetic sequences to taxonomic names. These databases vary in completeness and availability, depending on the taxonomic group studied and the genetic region targeted. The incompleteness of reference databases is an important argument to explain the nondetection by metabarcoding of species supposedly present. However, there exist further and generally overlooked problems with reference databases that can lead to false or inaccurate inferences of taxonomic assignment. Here, we synthesize all possible problems inherent to reference databases. In particular, we identify a complete, mutually nonexclusive list of seven classes of challenges when it comes to selecting, developing and using a reference database for taxonomic assignment. These are: (i) mislabelling, (ii) sequencing errors, (iii) sequence conflict, (iv) taxonomic conflict, (v) low taxonomic resolution, (vi) missing taxa and (vii) missing intraspecific variants. For each problem identified, we provide a description of possible consequences on the taxonomic assignment process. We illustrate the respective problem with examples taken from the literature or obtained by quantitative analyses of public databases, such as GenBank or BOLD. Finally, we discuss possible solutions to the identified problems and how to navigate them. Only by raising users' awareness of the limitations of metabarcoding data and DNA reference databases will adequate interpretations of these data be achieved.
Accuracy of the KontrolFlex AccuFile when used with the Root ZX electronic apex locator in vitro
Authors: Tittle Mia , Dunlap Craig A. , Scott Raymond , Arias Ana , Davis Scott , Peters Ove 
Published: December 2022

AbstractThe aims of this study were to determine the efficacy of the KontrolFlex™ Accufile™ compared to the READY•STEEL™ Flexofile® using an electronic apex locator and to evaluate the instrument's design via scanning electron microscopy. Actual canal lengths of 30 extracted teeth were determined under magnification. An alginate model was used to determine experimental canal lengths with the Root ZX II apex locator (EAL) and size #10 Accufiles and Flexofiles. Differences between actual lengths and experimental lengths were compared with Student's t test. The average experimental lengths were short of the actual length by −0.10 mm (±0.34) and −0.12 mm (±0.16) for the Accufile and Flexofile, respectively with no statistical difference (p > 0.05). SEM images revealed similar non‐cutting Batt tips and a square cross‐section for the Accufile and triangular for the Flexofile. Both files provided similarly high levels of reliability when used with the Root ZX II EAL.
The associations between women who are immigrants, refugees, or asylum seekers, access to universal healthcare, and the timely uptake of antenatal care: A systematic review
Authors: Saunders Samantha L. , Sutcliffe Kerry L. , McOrist Nathan S. , Levett Kate M. 
Published: December 2022

BackgroundThe World Health Organization (WHO) recommends that antenatal care (ANC) commence before 12 weeks' gestation to reduce the risk of obstetric and perinatal complications. Immigrants, refugees, and asylum seekers are at higher risk for late or non‐initiation of ANC, and exclusion from universal healthcare (UHC) may be a contributing factor.AimsThe aims were to synthesise evidence regarding uptake of ANC and to examine if this is associated with inadequate access to UHC and to evaluate the link between ANC and the risk of pregnancy outcomes in the immigrant, refugee and asylum seeker population.MethodsThe review was performed according to meta‐analysis of observational studies in epidemiology (MOOSE) guidelines. Five databases were systematically searched. Abstracts were screened against inclusion criteria, and eligible papers underwent data extraction by two independent reviewers per paper. The ROBINS‐I tool was used to assess risk of bias.ResultsTwelve studies were included in the final review. All studies reported that ANC was delayed for women who were classified as immigrants, refugees, and asylum seekers as per the WHO recommendations, and this was statistically significant compared to controls in 11 of 12 studies (P < 0.05). Findings regarding ANC uptake and pregnancy complications were too heterogeneous to conclusively report an association.ConclusionImmigrants, refugees and asylum seekers who are excluded from UHC present significantly later to ANC than receiving‐country‐born women with full access to UHC. The link between delayed ANC due to inadequate UHC access and pregnancy complications remains unclear due to the heterogeneous nature of the studies.
Pelvic floor training improves faecal incontinence and obstructed defaecation despite the presence of rectal intussusception
Authors: Albayati Sinan , Bhai Doleen , Descallar Joseph , Turner Catherine E. , Berney Christophe , Morgan Matthew J. 
Published: December 2022

AbstractBackgroundRectal intussusception is often observed in patients with faecal incontinence and obstructed defaecation. The aim of this study is to assess if pelvic floor training improves faecal incontinence and obstructed defaecation in patients with rectal intussusception.MethodsCase notes of all patients referred to Bankstown Hospital Pelvic Floor Clinic between 2013 and 2018 for the management of faecal incontinence and obstructed defaecation and rectal intussusception were retrospectively reviewed using a prospectively maintained database. St Mark's faecal incontinence and Cleveland clinic constipation scores were obtained from patients before and after they underwent pelvic floor training.ResultsOne hundred and thirty‐one patients underwent pelvic floor training at Bankstown Hospital Pelvic Floor Clinic between 2013 and 2018. Sixty‐one patients had rectal intussusception (22 low‐grade and 39 high‐grade). Median St Marks score improved following pelvic floor training from 8 to 1 (P < 0.001). Median Cleveland Clinic constipation score improved from 8 to 5 (P < 0.001). In patients with low grade rectal intussusception, pelvic floor training improved median St Mark's score from 3 to 0 (P = 0.003), whereas Cleveland Clinic constipation score improved from 9 to 7 (P < 0.001). In patients with high‐grade rectal intussusception, pelvic floor training improved median St Mark's score from 9 to 2 (P < 0.001), whereas median Cleveland Clinic constipation score improved from 8 to 4 (P < 0.001).ConclusionPelvic floor training without biofeedback therapy improves faecal incontinence and obstructed defaecation. Improvement in symptoms is unrelated to rectal intussusception observed on proctography or at examination under anaesthesia in these patients.
Editorial: ustekinumab during pregnancy ‐ reassuring but still not enough
Authors: Amiot Aurelien , Meyer Antoine , Carbonnel Franck 
Published: December 2022

LINKED CONTENTThis article is linked to Avni‐Biron et al papers. To view these articles, visit https://doi.org/10.1111/apt.17224 and https://doi.org/10.1111/apt.17282
Constitutive activity of the dopamine (D5) receptor, highly expressed in CA1 hippocampal neurons, selectively reduces CaV3.2 and CaV3.3 currents
Authors: Mustafá Emilio Román , McCarthy Clara Inés , Portales Andrea Estefanía , Cordisco Gonzalez Santiago , Rodríguez Silvia Susana , Raingo Jesica 
Published: December 2022

Background and PurposeCaV3.1‐3 currents differentially contribute to neuronal firing patterns. CaV3 are regulated by G protein‐coupled receptors (GPCRs) activity, but information about CaV3 as targets of the constitutive activity of GPCRs is scarce. We investigate the impact of D5 recpetor constitutive activity, a GPCR with high levels of basal activity, on CaV3 functionality. D5 recpetor and CaV3 are expressed in the hippocampus and have been independently linked to pathophysiological states associated with epilepsy.Experimental ApproachOur study models were HEK293T cells heterologously expressing D1 or D5 receptor and CaV3.1‐3, and mouse brain slices containing the hippocampus. We used chlorpromazine (D1/D5 inverse agonist) and a D5 receptor mutant lacking constitutive activity as experimental tools. We measured CaV3 currents and excitability parameters using the patch‐clamp technique. We completed our study with computational modelling and imaging technique.Key ResultsWe found a higher sensitivity to TTA‐P2 (CaV3 blocker) in CA1 pyramidal neurons obtained from chlorpromazine‐treated animals compared with vehicle‐treated animals. We found that CaV3.2 and CaV3.3—but not CaV3.1—are targets of D5 receptor constitutive activity in HEK293T cells. Finally, we found an increased firing rate in CA1 pyramidal neurons from chlorpromazine‐treated animals in comparison with vehicle‐treated animals. Similar changes in firing rate were observed on a neuronal model with controlled CaV3 currents levels.Conclusions and ImplicationsNative hippocampal CaV3 and recombinant CaV3.2‐3 are sensitive to D5 receptor constitutive activity. Manipulation of D5 receptor constitutive activity could be a valuable strategy to control neuronal excitability, especially in exacerbated conditions such as epilepsy.
Invisible targets: Conceptualizing U.S. Latine youth's exposure to family‐level vicarious racism
Authors: Martin Romero Michelle Y. , Stein Gabriela L. 
Published: December 2022

AbstractVicarious exposure to discrimination can result in multiple negative outcomes in youth. In this article, we offer a conceptual model that articulates the intersecting contextual factors and potential moderators for U.S. Latine youth's exposure to family‐level vicarious racism, and explore how that affects youth and family responses. We define and describe youth's exposure to family‐level vicarious racism, considering the ramifications of these experiences through family processes and cultural values. We conclude by arguing that research on discrimination and racism in Latine families needs to account for family‐level processes.