bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Incompatibility of Formalism and Negativism
Authors: McNay Lois 
Published: March 2022

Abstract
This chapter explores Rahel Jaeggi’s work on ethical forms of life and the central place it affords to criticism of regressive constellations of experience or blocked social relations. Her pragmatist emphasis on problem-solving and learning suggests that normatively efficacious critique consists in devising situationally specific strategies of empowerment rather than a single, all-encompassing theory of emancipation. The promise of Jaeggi’s negativist ethics is not fully realized, however, because of the way context transcendence is thematized through a ‘formal’ account of progress as rational continuity derived from Hegel. Jaeggi justifies this formalist approach on the grounds that it brings an acute sense of historicity back into critique and represents an idea of progress that is deflated, open and multifactorial. In fact, it has dehistoricizing effects in so far as the evaluative criteria of rational continuity undermine the attentiveness to experiential particularity that ostensibly drives the critique of lebensform. In principle, it would be possible for Jaeggi to mitigate tension between negativism and formalism by conceiving of context transcendence in dialogical terms that align more closely than her chosen formalist stance with the declared pragmatist and negativist orientation of her thought. On this alternative view, insight comes not come from measuring life-worlds against the abstract yardstick of progress, but rather is enabled by the way actors utilize the various resources—norms, meanings, and practices—that are present within a given form of life to expand their immanent perspective. Jaeggi forecloses such an option, however, by tendentiously dismissing experientially grounded critique as parochial standpoint theory.
The Politics of Informal Transport
Authors: Agbiboa Daniel E. 
Published: March 2022

AbstractThis chapter examines the role of the informal urban transport (“paratransit”) sector in Africa, as a groundwork for the rest of the book’s focus on the micropolitics of privately owned public transportation and exploitation on Lagos roads. The chapter argues that an analysis of the organization and politics of informal transport provisions afford a unique window onto the precarious unfolding of everyday, urban life in contemporary Africa, including issues of transport poverty, the stigmatized identity of transport operators, the extortionate and violent powers of politicized transport unions in cahoots with the state, and how plans to modernize public transit systems across Africa generally ignore the motley array of unregulated carriers who have become the fulcrum of Africa’s urban fabric. The paradox in this chapter is not lost: while Africa’s informal transport operators are often regarded as criminals, they are actually daily victims of corruption and crime themselves.
Nigeria’s Transport Mafia
Authors: Agbiboa Daniel E. 
Published: March 2022

AbstractThis chapter focuses on the origins and changing dynamics of the dreaded National Union of Road Transport Workers (NURTW) tax collectors—the mafia-like motor park touts (agberos)—and the intimidating and violent tactics and strategies they deploy to extort illegal fees of all sorts from informal transport operators in Lagos. Situating the emergence and reach of agberos within the widespread crisis of the structural adjustment program (SAP) introduced in 1986 in Nigeria, this chapter directly relates the transformation of agberos (from callers of passengers to violent extortionists) to their adverse incorporation into the NURTW as tax collectors and political thugs, which altered their initial role in the road transport sector. The chapter argues that efforts by the Lagos State Government to rid the roads of agberos since 1999 is inspired by its contested neoliberal urban reform project which responds to the logic of the market rather than the needs of the poor. Yet the role of “big politics” (in form of the unholy alliance between the NURTW and the state) helps explain the botched attempts to remove agberos from the roads.
The Paradox of Urban Reform
Authors: Agbiboa Daniel E. 
Published: March 2022

AbstractThis chapter examines the impact of the Lagos State Road Traffic Law of 2012 on the spaces of maneuvre and survival of informal transport operators in Lagos, with particular attention to motorbike-taxi (okada) drivers and their associations. On the one hand, the chapter explores the corrupt and brutal manner in which law enforcement agents in Lagos have enforced the Road Traffic Law. On the other hand, the chapter examines how and why the largest association of motorbike-taxi (okada) drivers in Lagos—the All Nigerian Autobike Commercial Owners and Workers Association (ANACOWA)—is appealing to state laws as a weapon of combat against the Lagos State Government and its law enforcement agents. The chapter sheds new light on how informal transport operators and their associations exercise agency and the right to the city in a collective attempt to intervene in the corrupt and unequal processes of neoliberal urban legislature and planning. Furthermore, the chapter demonstrates how urban reform in Africa can reproduce rather than address corruption and precarity in everyday life in the city.
A historical overview of music therapy for adults in mental health settings
Authors: Silverman Michael J. 
Published: March 2022

Abstract
There has been a shift in the perception of psychological interventions in the treatment of adults with mental health conditions. These interventions are now recognized as a crucial component of a comprehensive treatment approach. Music therapy is a healthcare profession with tremendous breadth. As defined by the American Music Therapy Association, music therapy is the clinical use of music interventions to accomplish individualized goals within a therapeutic relationship by a credentialed professional who has completed an approved music therapy program. This chapter first provides readers with a brief overview of the music therapy profession for non–music therapist readers by focusing on the breadth of the field, as well as the education and clinical training for those in the profession. The chapter then describes of the development of the music therapy profession and different types of mental health settings so readers will have context for the following chapters. Designed for both administrators and music therapists, the chapter also includes ways to fund music therapy in adult mental health settings.
Therapeutic mechanisms within music therapy for adults with mental health conditions
Authors: Silverman Michael J. 
Published: March 2022

Abstract
This chapter describes factors that influence therapeutic outcome related to attendance and participation, as well as characteristics of both the service user and therapist. While researchers and clinicians have developed numerous taxonomies to describe mechanisms responsible for therapeutic change, understanding mechanisms of therapeutic change can allow the therapist to program for, implement, and identify and use these factors to enhance therapeutic outcome. This chapter describes how music therapist can use cognitive factors (universalization, insight, and modeling), affective factors (acceptance, altruism, and transference), and behavioral factors (reality testing, ventilation, and interaction) to facilitate an environment conducive to service user change. These subfactors are described in detail and can lead to therapeutic growth, change, stronger therapeutic relationships, and better outcomes.
The therapeutic relationship and alliance
Authors: Silverman Michael J. 
Published: March 2022

Abstract
New to the second edition of this book, this chapter describes the therapeutic relationship and alliance, as well as ways to facilitate them. The therapeutic relationship and alliance represent integral components of successful therapy and often lead to augmented therapeutic outcomes. Because of the use of music as a medium for initiating therapeutic change, music therapists can efficiently and effectively establish a positive alliance with their service users. This chapter provides an overview of the theoretical and empirical literature related to alliance in therapy, and it concludes with specific suggestions music therapists can implement to augment the likelihood of a positive alliance and ensuing therapeutic outcome.
Music therapy interventions in adult mental health settings
Authors: Silverman Michael J. 
Published: March 2022

Abstract
There are numerous potential interventions available for music therapists to help adults with mental health conditions reach their clinical objectives. This chapter describes different music therapy interventions that can be used in adult mental health settings and how to deliver them using an illness management and recovery approach. Focusing on lyric analysis and songwriting, the chapter describes how aspects of the music and structure can be used to ensure service users have a successful experience. It is essential for the music therapist to make educational and therapeutic material explicit so people with mental health conditions are able to generalize knowledge and skills learned in music therapy to other aspects of their lives.
Introduction
Authors: Hayton Jeff 
Published: March 2022

Abstract
Culture from the Slums opens with an overview of punk and a detailed explanation of the divided German context. In the process, it makes three main claims. First, that punk has substantially influenced politics, society, and culture in divided Germany during the 1970s and 1980s and helps explain the success of democracy in West Germany and the failure of socialism in East Germany. Second, that alternative culture and authenticity are crucial for understanding the subculture and these decades, and explains why and how they drove the cultural experimentation that defines this era. And third, there were considerable similarities between East and West Germany in popular music production and consumption, parallels suggesting a certain subcultural convergence across the Iron Curtain in the last decades of the Cold War. Along with discussions of methodology and definitions, the introduction outlines the study’s historiographical interventions and punk’s importance for understanding postwar German history.
Integration and Collapse
Authors: Hayton Jeff 
Published: March 2022

Abstract
Chapter 8 investigates how, unable to eliminate punk coercively, the communist regime instead sought to dilute its criticisms through integration as the East German state promoted punk to generate support in the last years of its existence. Following a series of violent attacks by Skinheads and internal encouragement by cultural authorities, the state abruptly reversed its condemnations of punk in February 1988 and instead sought to win youth subcultures to the regime. Flooding the socialist market with groups known as “die anderen Bands” (the Other Bands), punks appeared in the media, released records, starred in films, and even played in the West as the state instrumentalized the genre to generate popularity, even if youths used state support to continue undermining the regime. However, state partnership also led to crisis which split the subculture between those taking advantage of the increased opportunities and those who rejected any state collaboration as a betrayal. Thus, accompanying the collapse of the SED regime in 1989, were acrimonious rifts dividing the East German subculture, splits and disagreements which have had long-lasting consequences for punk ever since.
Statistical entrepreneurs: the political work of infrastructuring the SDG indicators
Authors: Bandola-Gill Justyna 
Published: March 2022

AbstractGoverning by indicators has emerged as the predominant mode of global public policy. Consequently, global governance has become a field in which different indicators compete for policymakers’ and public attention. This begs a question—what makes some indicators successful when others become irrelevant? This paper explores this problem through the inquiry into the measurement of multidimensional poverty in Sustainable Development Goal 1 (“End poverty in all its forms everywhere”). In the field historically dominated by the World Bank’s dollar-per-day metric (currently 1.9$), multidimensional poverty measurement gained prominence, becoming one of the key measures of global poverty. By tracking the pathways to success of multidimensional poverty measurement—through qualitative interviews with actors in International Organisations this paper argues that the key quality of successful indicators is their ability to become parts of the broader epistemic infrastructure, linking political institutions, actors (including experts and policymakers), and data and statistics. The paper brings the focus on a specific set of actors—statistical entrepreneurs—who advocate for innovations in measurement and work toward creating such infrastructures, thus indirectly promoting new policy ideas reflected in the metrics.
Brain Pericytes Acquire Stemness via the Nrf2-Dependent Antioxidant System
Authors: Sakuma Rika , Kobayashi Miku , Kobashi Rui , Onishi Mako , Maeda Mitsuyo , Kataoka Yosky , Imaoka Susumu 
Published: March 2022

Abstract
Pericytes (PCs) are a mural support cell population elongated at intervals along the walls of capillaries. Recent studies reported that PCs are multipotent cells that are activated in response to tissue injury and contribute to the regenerative process. Using a C.B-17 mouse model of ischemic stroke, it has been proposed that normal brain pericytes (nPCs) are converted to ischemic pericytes (iPCs), some of which function as multipotent stem cells. Furthermore, oxygen-glucose deprivation (OGD) promoted mesenchymal-epithelial transition in nPCs; however, nestin was not induced under OGD conditions. Therefore, further studies are needed to elucidate the PC reprogramming phenomenon. We herein isolated nPCs from the cortex of C.B-17 mice, and compared the traits of iPCs and nPCs. The results obtained showed that nPCs and iPCs shared common pericytic markers. Furthermore, intercellular levels of reactive oxygen species and the nuclear accumulation of nuclear factor erythroid-2-related factor 2 (Nrf2), a key player in antioxidant defenses, were higher in iPCs than in nPCs. OGD/reoxygenation and a treatment with tBHQ, an Nrf2 inducer, increased nestin levels in nPCs. Moreover, epithelial marker levels, including nestin, Sox2, and CDH1 (E-cadherin) mRNAs, were elevated in Nrf2-overexpressing PCs, which formed neurosphere-like cell clusters that differentiated into Tuj1-positive neurons. The present results demonstrate that oxidative stress and Nrf2 are required for the generation of stem cells after stroke and will contribute to the development of novel therapeutic strategies for ischemic stroke.
Arterial Injury Portends Worse Soft Tissue Outcomes and Delayed Coverage in Open Tibial Fractures
Authors: Bi Andrew S. , Fisher Nina D. , Parola Rown , Ganta Abhishek , Egol Kenneth A. , Konda Sanjit R. 
Published: March 2022

Objectives:
To investigate if any injury to the three primary branches of the popliteal artery in open tibia fractures lead to increased soft-tissue complications, particularly in the area of the affected angiosome.

Design:
Retrospective cohort comparative study

Setting:
Two academic level one trauma centers

Patients/Participants:
Sixty-eight adult patients with open tibia fractures with a minimum one-year follow up;

Intervention:
N/A

Main Outcome Measurements:
Soft-tissue outcomes as measured by wound healing (delayed healing, dehiscence, or skin breakdown) and fracture related infection (FRI) at time of final follow-up.

Results:
Eleven (15.1%) tibia fractures had confirmed arterial injuries via CTA (7), direct intraoperative visualization (3), intraoperative angiogram (3). Ten (91.0%) were treated with ligation and 1 (9.1%) was directly repaired by vascular surgery. Ultimately, 6 (54.5%) achieved radiographic union and 4 (36.4%) required amputation performed at a mean of 2.62 ± 2.04 months, with one patient going on to nonunion diagnosed at 10 months. Patients with arterial injury had significantly higher rates of wound healing complications, FRI, nonunion, amputation rates, return to the OR, and increased time to coverage or closure. After multivariate regression, arterial injury was associated with higher odds of wound complications, FRI, and nonunion. Ten (90.9%) patients with arterial injury had open wounds in the region of the compromised angiosome, with 7 (70%) experiencing wound complications, 6 (60%) FRIs, and 3 (30%) undergoing amputation.

Conclusions:
Arterial injuries in open tibia fractures with or without repair, have significantly higher rates of wound healing complications, FRI, delayed time to final closure, and need for amputation. Arterial injuries appear to effect wound healing in the affected angiosome.

Level of Evidence:
Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.
CircFOXK2 enhances tumorigenesis and immune evasion in non–small cell lung cancer by miR-485-5p/PD-L1 axis
Authors: Zhang Nan , Fan Jian , Deng Zhiping 
Published: March 2022

Background
Circular RNAs (circRNAs) serve a key role in lots of cancers. The outcomes of upregulated circular RNA forkhead box K2 (circFOXK2) on non–small cell lung cancer (NSCLC) persisted uncertainly. In this study, the role of circFOXK2 in NSCLC was inspected.

Methods
The abundances of circFOXK2, microRNA-485-5p (miR-485-5p) and programmed cell death ligand-1 (PD-L1) were confirmed by quantitative real-time PCR and western blot. Cell counting kit-8 (CCK-8) assay and clonogenic assay were accomplished to conclude the proliferation of NSCLC cells. Wound healing and transwell assays were implemented to evaluate cell migration and invasion. Lactate dehydrogenase (LDH) cytotoxicity assay was enforced to quantify the cytotoxicity of CD8+ T cells. Flow cytometry assay was employed to detect apoptosis. Besides, the mice experiments were utilized for in vivo tumorigenesis analysis. Dual-luciferase reporter assay was carried out to reveal the associations between miR-485-5p and circFOXK2 or PD-L1.

Results
CircFOXK2 and PD-L1 levels were augmented in NSCLC. CircFOXK2 targeted miR-485-5p, which could bind to PD-L1. CircFOXK2 served a key role in NSCLC tumorigenesis and cytotoxicity of CD8+ T cells. MiR-485-5p inhibition or PD-L1 overexpression abolished the inhibitory effects of circFOXK2 lack on NSCLC tumorigenesis and cytotoxicity of CD8+ T cells.

Conclusion
CircFOXK2 sponged miR-485-5p to stimulate PD-L1 and expedited NSCLC development.
In-silico drug-likeness analysis, ADME properties, and molecular docking studies of cyanidin-3-arabinoside, pelargonidin-3-glucoside, and peonidin-3-arabinoside as natural anticancer compounds against acting receptor-like kinase 5 receptor
Authors: Kurter Hasan , Mert-Ozupek Nazli , Ellidokuz Hulya , Calibasi-Kocal Gizem 
Published: March 2022

Background
The aim of the study was in-silico drug-likeness analysis, absorption, distribution, metabolism, and excretion (ADME) properties, and molecular docking studies of anthocyanins as natural anticancer compounds against acting receptor-like kinase 5 (ALK5) receptor. Transforming growth factor-β (TGF-β) plays an essential role in various cellular processes. Increased expression of TGF-β and its receptor TGFβR-I (i.e. ALK5) have been associated with poor prognosis in cancer patients.

Methods
The drug-likeness activity of anthocyanins was performed using SwissADME tool. Molecular docking studies were carried out by using the Autodock Vina 1.5.6 tool.

Results
The results revealed that cyanidin-3-arabinoside (C3A), pelargonidin-3-glucoside (P3G), and peonidin-3-arabinoside (P3A) were able to use both Lipinski’s rule of five and Ghose variations. The binding energies of C3A, P3G, and P3A against ALK5 were found as −8.0, −8.3, and −8.4 kcal mol−1, respectively.

Conclusion
These selected anthocyanins have shown higher binding energies than known inhibitors to the ALK5 receptor. Further in-vitro and in-vivo studies were strongly recommended to clarify the whole mechanism.
What Do We Know About Shoulder Injury Related to Vaccine Administration? An Updated Systematic Review
Authors: MacMahon Aoife , Nayar Suresh K. , Srikumaran Uma 
Published: March 2022

Abstract

Background
Shoulder injury related to vaccine administration (SIRVA) is postulated to be an immune-mediated inflammatory response to a vaccine antigen injected into or near the subacromial bursae or synovium, leading to shoulder pain and dysfunction. The number of studies on this topic is rapidly increasing. Recent comparative studies have reported conflicting conclusions, which suggests that a systematic review of the best-available evidence may be helpful.

Questions/purposes
In this systematic review, we asked: What are the (1) clinical characteristics, (2) diagnoses, and (3) management approaches and outcomes reported in association with SIRVA?

Methods
A search was performed on October 4, 2021, of the PubMed and Medline databases for studies related to SIRVA. Inclusion criteria were English-language comparative studies, case series, and case reports that involved shoulder pain occurring after vaccination. Studies of exclusively neurologic conditions after vaccination were excluded. Forty-two studies met the eligibility criteria, including three retrospective comparative studies (72 patients and 105 controls), five database case series (2273 patients), and 34 case reports (49 patients). Study quality was assessed for the database case series and retrospective comparative studies using the Methodological Index for Non-randomized Studies tool.

Results
Among patients in the case reports, the median age was 51 years (range 15-90 years), and 73% (36 of 49) were women. BMI was reported for 24% of patients (12 of 49) in case reports, with a median of 23.5 kg/m2 (range 21-37.2 kg/m2). The most common symptoms were shoulder pain and reduced ROM. The most common diagnoses were shoulder bursitis, adhesive capsulitis, and rotator cuff tears. The most frequent management modalities included physical or occupational therapy, NSAIDs, and steroid injections, followed by surgery, which was generally used for patients whose symptoms persisted despite nonsurgical management. Full resolution of symptoms was reported in 2.9% to 56% of patients.

Conclusion
The association between inflammatory conditions of the shoulder (such as bursitis) and vaccination appears to be exceedingly rare, occurring after approximately 1:130,000 vaccination events according to the best-available comparative study. Currently, there is no confirmatory experimental evidence supporting the theory of an immune-mediated inflammatory response to vaccine antigens. Although the clinical evidence is limited, similar to any bursitis, typical treatments appear effective, and surgery should rarely be performed. Additional research is needed to determine the best injection technique or evaluate alternate injection sites such as the anterolateral thigh that do not involve positioning a needle close to the shoulder.