bluuebunny/crossref_metadata_2025_split huggingface dataset:
Monitorização da pressão intracraniana: importância da abordagem do profissional enfermeiro
Authors: Andrade Diêgo Correia de , Oliveira Larissa Karlla Nascimento de , Anacleto Maria Cecília de Souza , Silva Jessica Souza Lopes da , Antunes Mateus da Silva Matias 
Published: November 2022

Objetivo: avaliar o nível de conhecimento de profissionais enfermeiros sobre a monitorização da pressão intracraniana em pacientes neurocríticos.
Método: pesquisa de campo, tipo exploratório e descritivo com abordagem quantitativa. Dados coletados por meio de questionário durante o mês de setembro de 2019. Compuseram a amostra 55 enfermeiros. A pesquisa foi aprovada pelo Comitê de Ética em Pesquisa, parecer nº 3.457.431, e realizada em unidade de terapia intensiva adulto, Hospital Público do Estado da Paraíba.
Resultados: 55% dos enfermeiros realizam aplicação da Escala de Coma de Glasgow, aguardando um intervalo mínimo de quatro a cinco meias–vidas após a suspensão dos fármacos com ação depressora do sistema nervoso central e bloqueadores neuromusculares. Ademais, 75% dos entrevistados reconhecem o parâmetro de normalidade da pressão intracraniana.
Considerações Finais: foi observada a necessidade da atualização técnico-científica de enfermeiros sobre os cuidados holísticos de pacientes neurocríticos, a fim de promover melhor qualidade na assistência sistematizada de enfermagem intensiva.
Ocorrência de near miss materno em uma Unidade de Terapia Intensiva de um hospital público
Authors: Foureaux Patricia , Augusta Marques Bonazzi Vera Cristina 
Published: November 2022

Objetivo: Verificar a ocorrência de near miss materno pelos critérios estabelecidos pela Organização Mundial de Saúde em pacientes internadas em Unidade de Terapia Intensiva.
Metodologia: Trata-se de um estudo transversal, quantitativo, descritivo e retrospectivo. A coleta de dados foi realizada em unidade de terapia intensiva no período de 1º de janeiro a 31 de julho de 2020. Foram incluídas mulheres que apresentaram pelo menos um critério de
near miss.
Resultados: Foram identificados nove casos de near miss materno. A maior ocorrência deles foi observada em mulheres acima de 30 anos, casadas e pardas. Quanto às complicações, houve predominância da hipertensiva, com índice elevado de pré-eclâmpsia e síndrome HELLP.
Conclusão: Espera-se que os resultados apresentados neste estudo contribuam para ampliar o conhecimento sobre a identificação, através dos critérios da OMS, de casos de
near miss materno, tornando-o ferramenta essencial e estratégia promissora para a redução da mortalidade materna.
Diagnósticos e cuidados de enfermagem relacionados ao puerpério: uma revisão integrativa
Authors: Silva Beatriz Lages , Malta Yanka Larissa de Souza , Alvim André Luiz Silva 
Published: November 2022

Objetivo: levantar na literatura os principais diagnósticos e cuidados de enfermagem utilizados durante a assistência à puérpera. Metodologia: trata-se de uma revisão integrativa da literatura. Resultados: os diagnósticos prevalentes foram o de dor aguda, conforto prejudicado, intolerância à atividade e disposição para amamentação melhorada. Quanto aos cuidados de enfermagem encontrados, os estudos mostraram a prevalência dos cuidados físicos em detrimento dos cuidados psicossociais, sendo esta, uma das fragilidades na assistência às puérperas. Conclusão: este estudo identificou os principais diagnósticos e cuidados de enfermagem relacionados ao puerpério. No entanto, a Sistematização da Assistência de Enfermagem e o Processo de Enfermagem não se limitam a essas duas etapas no contexto da assistência à saúde.
Desafios para a socioeducação brasileira no início da pandemia
Authors: Guimarães Lyara Correia , Silva Bruno César da , Buoso Fernanda Papa , Bazon Marina Rezende 
Published: November 2022

A pandemia da COVID-19 trouxe impactos na aplicação e execução das medidas socioeducativas, a partir de ações determinadas pelo Conselho Nacional de Justiça (CNJ). Neste artigo, tais ações são discutidas considerando tanto o seu amparo legal quanto o seu embasamento científico. Assim, foram pontuados aspectos relevantes para garantia de direitos e promoção do desenvolvimento integral dos adolescentes em conflito com a lei.
An Anti-Leukotriene Strategy to Reduce the Consequences of a Hyperinflammatory Response in COVID-19
Authors: Ищенко О.В. 
Published: November 2022

В настоящее время пандемия COVID-19 стала серьезным вызовом для общественного здравоохранения. Сохраняются постоянные усилия по поиску терапевтических возможностей потенциальных методов лечения COVID-19. Однако, несмотря на все эти усилия, эффективной терапии до сих пор не существует, и это остается глобальной проблемой для научного сообщества. Важную роль в индукции и персистенции гипериммунного воспаления при COVID-19 играют лейкотриены. Антилейкотриеновая терапия является перспективным вариантом лечения COVID-19 и его последствий. Фаворитом здесь является блокатор лейкотриеновых рецепторов – монтелукаст. Имеющиеся на сегодняшний день результаты исследований обеспечивают четкое научное обоснование использования монтелукаста отдельно или в сочетании с противовирусной терапией при COVID-19.
The COVID-19 pandemic has now become a major global public health disaster. There is persistence and ongoing efforts to find therapeutic options for potential treatments for COVID-19. However, despite all these efforts, there is still no effective therapy, and this remains a global problem for the scientific community. Leukotrienes play an important role in the induction and persistence of hyperimmune inflammation in COVID-19. Antileukotriene therapy is one of the attractive treatment options for COVID-19 and its consequences. The favorite here is the leukotriene receptor blocker – montelukast. The research results available to date provide a clear scientific rationale for the use of montelukast alone or in combination with antiviral therapy for COVID-19.
Dampak Environmental Performance dan Environmental Disclosure terhadap Profitabilitas Perusahan
Authors: Sparta Sparta , Ayu Dita 
Published: November 2022

This study aimed to examine the impact of environmental performance and environmental disclosure to profitability. Profitability is measured by Return on Asset, environmental performance by PROPER Rating, while environmental disclosure by Corporate Disclosure Indeks. This research also used size and leverage as control variables. Samples generated from The SRI-HATI index from 2010 to 2014, which in total 50 observations. The research proves that the environmental performance, company size and leverage have a significant negative impact on profitability, while environmental disclosure does not impact on the profitability of the company. These results have implications especially to companies and investors related to the costs incurred by the company for improvement of environmental performance and disclosure.
PENGARUH KUAITAS LAYANAN, HARGA, DAN LOKASI TERHADAP KEPUASAN KONSUMEN (STUDI KASUS PADA BAKSO MERCON BUYAN)
Authors: Sari Nopita Mayang , Ekowati Sri 
Published: November 2022

This study aims to determine the effect of service quality, price, and location on consumer satisfaction, a case study on Bakso Mercon Bu'yan. The problem of this study is whether the quality of service, price, and location affect consumer satisfaction. This study took research samples of 100 consumers by using accidental sampling. While, data collection techniques by giving questionnaires. For data analysis technique used multiple linear regression, instrument test, coefficient of determination and hypothesis test.The results showed that the price had a positive effect on consumer satisfaction, which indicated the price given accordance with the customer satisfaction as shown with the value of benefits obtained, which make consumers have not objection to make purchasing decisions. Similarly, Price has a positive influence on consumer satisfaction. This means that if this is in accordance with the customer satisfaction given. Furthermore, the location variable showed a positive influence on consumer satisfaction, which indicated if the location is more strategic then customer satisfaction will also increase. Thus, the results of research sum it all that service quality, price and location have partially and simultaneously effects on consumer satisfaction at Bakso Mercon Bu'yan.
ANALISIS STRATEGI PEMASARAN PADA PERUMAHAN PT. PESONA ALAM SINERGI
Authors: Arya Muhammad , Putri Afifah Indah , Nedian Agung , Pebriandi Grense 
Published: November 2022

Every company wants to achieve high sales every year and to achieve these sales, an attractive and accurate marketing and strategy is definitely needed so that consumers can trust the products and buy products from the company. PT. Pesona Alam Sinergi is a company that sells subsidized housing, the company PT. This Natural Enchantment of Synergy has been established since 3 years ago or in 2019. In carrying out marketing activities, a company has several goals to be achieved, both short-term goals and long-term goals. In the short term usually to win the hearts of consumers, especially for newly launched products. Meanwhile, in the long term, it is done to maintain existing products in order to continue to exist. In general, to understand the concept of marketing strategy, it is necessary to introduce an understanding of the concept of marketing strategy. Based on the SWOT analysis for Internal factors, a score of 3.03 was obtained for the strength factor which had the highest score was "experienced development" with a score of 0.77, and for the weakness factor which had the highest score was "the facilities provided were incomplete" with a score of 0.44. Then the IFE result value is 3.03. Based on the SWOT analysis for external factors, a score of 2.74 was obtained for the opportunity factor which had the highest score was "a large target market" with a score of 0.80. And for the threat factor that has the highest score is "increase in material prices" with a score of 0.50. Then the value of the EFE result is 2.74.Keywords: Marketing strategy, Housing
AKTIVITAS MANAJEMEN PEMASARAN DI UMKM KERIPIK PISANG DAN DONAT AISHA
Authors: Talibonso Linkan Dwi Putri , Adesi Fella Piona , Fatihatunnisa Fatihatunnisa , Setiadi Yulius Wahyu 
Published: November 2022

Marketing is an important activity carried out by companies to maintain their companies, develop and earn profits or profits. The marketing process begins before the goods are produced. The purpose of this study is to find out how marketing management activities and what strategies are used in UMKM Banana Chips and Aisha Donuts. The method used in this research is descriptive qualitative. This research information can be obtained from interview and observation techniques. The conclusion from the conclusion that marketingmanagement activities in UMKM banana chips and aisha donuts are stillsaid to benot good because there is still a lack of human resources. And the marketing strategy used is business to business (B2B) to maintain their sales. Suggestions for UMKM for banana chips and aisha donuts are more human resources so that their marketing activities are more controlled. Keywords : marketing management, marketing strategy, B2B
Technology Report: Optical Bar Code for Internet Access Application based on Optical camera communication and Bluetooth Control
Authors: Wen Shangsheng , Liu Manxi , Chen Yanyi , Chen Yirong , An Futong , Chen Yingcong , Guan Weipeng 
Published: November 2022

<p>We demonstrate an internet access application based on optical camera communication and bluetooth. The app will access the website while the camera in the phone receives the optical signal. © 2022 The Author(s)</p>
Effect of feeding camel colostrum extract on some Reproductive Hormones in Female Rats
Authors: Sabeeh Shaimaa Abbas 
Published: November 2022

Finding natural products to prevent or reduce the reproductive system problems is still a goal to many researchers. Natural substances are characterized by their high safety marginscompared to the synthetic ones. The aim of this research was to focus on the effect of camel colostrum extract feeding on some reproductive hormones represented here by Follicle-stimulating hormone ( FSH ) & Luteinizing hormone ( LH ) in female rats. Amounts of 30 ml each of Iraqi camel colostrum were collected post-parturition at 0, 6, and 12 hours in sterile containers and sent directly in icebox to a laboratory. The colostrum samples were centrifuged twice at 5000 rpm for 10 minutes. The supernatants were difiltrated, and the extracts were refrigerated at 4ºC until use. Twenty albino rats were grouped randomly into four equal groups (five rats per group). The control group (CG) was given tap water only, while the treatment groups (0 G, 6G, and 12G) were given 0.1 ml of the extract orally for one week. After 30 days, the rats were sacrificed. Then quickly, blood samples were collected and immediately spun using a centrifuge at 5000 rpm for 5 minutes to collect serum. Finally, serum was measured for the level of FSH and LH. The levels of the FSH & LH showed significant increases in all treated groups compared to the control group
Ameliorative effect of soybean lecithin on the liver enzymes of rats supplemented with high cholesterol
Authors: Alshammary Sarah Mohammed , Khaleel Luma Waleed 
Published: November 2022

The present experiment was investigated to study the ameliorative role of soybean lecithin specially phosphatidylcholin on liver enzymes (ALT) and (AST) in intact and hypercholesterolemic infected rats.Thirty two adult male rats have been used in this study, were randomly selected and equally divided in to four groups as follows C, T1 , T2, T3.They were treated orally (daily) for 42 days as follows; C:control group, were given distilled water by gavage needle, T1: rats of this group were given soybean lecithin only (430mg\kg\day) orally; T2:rats of this groups were given only cholesterol (10gm\day) orally; T3: rats of this groups were given soybean lecithin (430mg\kg\day) orally, and supplemented with high cholesterol (10gm\day) orally within diet.The daily supplementation of soybean lecithin induces a significant decrease (p > 0.05) in liver enzymes (ALT & AST) as compared with (T2) group which has seen remarkable rise in these enzymes respectively. Moreover, the histopathological examination showed results referred that cholesterol effects significantly on the liver cells by causing sever fatty changes characterized by variable size round clear spaces in the hepatocytes. Also, there is a mononuclear cells aggregation in liver parenchyma and congested blood vessels without any fatty vacuoles in (T2)..
Determination of Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MAC) of seed methanolic extract of Peganumharmala L. against Gram negative bacteria
Authors: Al-zeiny Saadia Saleh Mehdy 
Published: November 2022

Peganum harmala L. (Zygophyllaceae) used in traditional medicine of Iraq and itis one of the most famous medicinal plants. The most bacteria pathogen is resistance for synthesis antibiotic drugs resulting from abuse uses of the patient or produce resistance strains for microorganism therefor, the aim of this search is the effect antibacterial of seed alcoholic extract of peganum harmala on some Gram negative bacteria pathogen. Methods: The broth serial dilution assay method determined the minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of seed methanolic extract of Peganum harmala were tested for antibacterial effect against bacterial isolates (salmonlla enteric , klebsiela pneumonia multidrugresitant E. Coli and highly resist E.coli), used phytochemical analysis of seed mathanolic extrac of peganumharmala. Result: showed good antibacterial activity against strain Salmonella enteric and Klebsella pneumonia, were MBC at concentration (25 mg/ml) and no effect of low concentration of MIC. The MBC value against strain multidrugresistant Escherichia coli, was at concentration (3.125 mg/ml) and MIC at (25 and 12.5 mg/ml), while MBC of highly resist Escherichia coli was in (12.5mg/ml) and MIC value at 50 mg/ml compared with standard antibiotics synthesis. Phytochemical analysis of component seed methanolic extract of peganumharmala showed presence of flavonoids, alkaloids, saponins, tannins, glycosides, terpenoids and steroids.
Highlights on Ocular Toxicity of Immune Checkpoint Inhibitors at a US Tertiary Cancer Center
Authors: Mazharuddin Anam A. , Whyte Andrew T. , Gombos Dan S. , Patel Nimisha , Razmandi Azadeh , Chaudhry Amina L. , Al-Zubidi Nagham S. 
Published: November 2022

ABSTRACT

Introduction
Immune checkpoint inhibitors (ICIs) have improved prognosis in advanced malignancies; however, they may be associated with extensive ocular immune-related adverse events (irAEs) that are sight threatening. Our study aimed to identify the presentation, characteristics, management, and clinical outcomes of ocular irAEs. Methods: In this retrospective, observational case series, we reviewed the medical records of 1280 patients at a large US tertiary cancer center between 2010 and 2020. Results: We identified 130 patients who presented with ocular irAEs (10%) with 69 males (53%) and 61 females (47%). The mean time to toxicity was 6.1 months. Adverse events include corneal toxicity (31%), neuro-ophthalmic (14%), uveitis and scleritis (13%), retinopathy (13%), periocular disorders (11%), and others. IrAEs occurred most frequently with nivolumab (26%). Most ocular irAEs were treated with topical therapy. Advanced cases required systemic corticosteroids and even cessation of ICIs. Conclusion: Our cohort is a large case series highlighting the increased potential of ocular toxicity associated with ICIs. Prompt recognition and management of ocular irAEs can minimize their effect.
Use of Ocudox™ or hypochlorous acid to inactivate SARS-CoV-2 as an alternative to alcohol-based products
Authors: Lorca-Oró Cristina , Roca Núria , Martín Carmen Gomez , Abad Xavier 
Published: November 2022

Objective: The main route of entry of SARS-CoV-2 which responsible of COVID-19 is through the nasal, oral, or conjunctival mucosa and droplets or aerosols transmit the virus. Even if transmission through fomites is considered unlikely, hand hygiene is important to minimize this and other infections, especially in certain scenarios as healthcare facilities and crowded places as public transport or social events.
Material and methods: In this study, we assess and compare the virucidal efficacy of HOCl solutions against SARS-CoV-2 at different time-points. a nasopharyngeal swab collected from an 89-year-old male patient during March 2020 in Catalonia, Spain (GISEAD ID EPI_ISL_510689). The virus was propagated in Vero E6 cells (ATCC CRL-1586) cultured in Dulbecco’s modified Eagle medium (DMEM). A total of 24 plastic plates (35 mm SPL Ref. PLC20035) for the first study, and 12 plates for the second one, were prepared. One day before titration, 96-well plates were prepared with Vero E6 cells. The day of titration, two replicates of five 10-fold serial dilutions of each sample were performed. Plates were incubated at 37°C and 5% CO2 for 7 days, and afterward, SARS-CoV-2-induced cytopathic effect (CPE) was determined under light microscope
Results: The virucidal effect by means of TCID50/mL found after HOCl treatment at different concentrations and times tested. Logarithmic reduction (logR) and the correspondent percentage of inactivation (%) were calculated compared to the untreated controls (desiccated SARS-CoV-2 with water or media). All tested concentrations were able to partially inhibit SARS-CoV-2
Conclusion: Our studies showed that HOCl products represent a valid virucidal alternative to inactivate SARS-CoV-2 potentially present in skin or surfaces.
Evaluasi Pelelangan Proyek Konstruksi Dengan Aplikasi Metode Fuzzy Set
Authors: Asna I Made , Angga Diputera I Gede 
Published: November 2022

Evaluasi pelelangan proyek konstruksi dengan aplikasi metode fuzzy set adalah suatu metode evaluasi pemilihan penyedia jasa untuk melaksanakan proyek konstruksi dengan menerapkan metode fuzzy set dalam proses evaluasi potensi kinerja penyedia jasa. Sehingga mendapatkan penyedia jasa yang mempunyai kinerja sesuai dengan kriteria yang ditetapkan.Berdasarkan hasil analisis data diperoleh tingkat pentingnya preferensi kriteria dari penilaian panitia pelelangan terhadap preferensi kriteria harga penawaran menurut mereka lebih penting dari preferensi kriteria kemampuan teknis, sedangkan kontribusi potensi harga penawaran terhadap seluruh kriteria penilaian sebesar 0,3723 dan kontribusi potensi kinerja teknis terhadap seluruh kriteria penilaian sebesar 0,1277. Urutan rangking masing-masing penyedia jasa pada pelelangan tersebut sebagai berikut: penyedia jasa alternatif A1, A2, A3, A4, A5, A6, A7, A8, A9, A10, dengan skor akhir masing-masing penyedia jasa berturut-turut: 0,5771., 0,5696., 0,5329., 0,5202., 0,5055., 0,4974., 0,4898., 0,4835., 0,4826., 0,4745.
Penyediaan Ruang Parkir dalam Memenuhi Kebutuhan Pengguna Parkir di UPT Pengujian Kendaraan Bermotor Dinas Perhubungan Kota Denpasar
Authors: Astati Sukawati Ni Ketut Sri , Suryadarmawan I Gusti Agung Gde , Suarmawati Kadek Andiyani 
Published: November 2022

Keberadaan pengujian kendaraan bermotor dirasakan cukup penting sebagai aspek yang harus dilakukan dan diterapkan. Salah satunya terletak di daerah Desa Suwung Kauh Denpasar Selatan yaitu UPT Pengujian Kendaraan Bermotor Dinas Perhubungan Kota Denpasar. Dimana dalam bidang pelayanan publik ini dihadapkan pada permasalahan yaitu kapasitas lahan parkir yang terdapat di kawasan UPT Pengujian Kendaraan Bermotor Dinas Perhubungan Kota Denpasar. Adapun hal - hal yang akan disurvei adalah jumlah kendaraan wajib uji yang parkir diareal kantor UPT Dinas Perhubungan Kota Denpasar. Dari analisis yang dilakukan didapatkan hasil volume kendaraan yang parkir pada hari senin yaitu 119 kendaraan , sedangkan pada hari jumat yaitu 84 kendaraan. Akumulasi parkir tertinggi terjadi pada pukul 10.30 - 10.45 wita yaitu sebesar 15 kendaraan pada saat hari senin, sedangkan akumulasi tertinggi pada hari jumat terjadi pada pukul 09.15 - 09.30 yaitu sebesar 12 kendaraan. Turnover (Tingkat Pergantian parkir) adalah 3 kendaraan/stall/jam. Rata-rata lamanya parkir kendaraan adalah 0,11 jam/kendaraan. Kapasitas parkir yaitu 90 kendaraan. Indeks parkir yaitu 150%. Perhitungan kebutuhan luas lahan parkir adalah 637,5 m2. Kapasitas parkir dengan perluasan lahan adalah 136 kendaraan. Indeks parkir dengan perluasan adalah 100% (memenuhi syarat minimal).