bluuebunny/crossref_metadata_2025_split huggingface dataset:
Foot extension and retraction in the clamCalyptogena okutaniiwithout any Keber's valve: an inflatable fastener bag model
Authors: Seo Eriko , Ohishi Kazue , Imaizumi-Ohashi Yoshie , Yokoi-Hayakawa Mika , Yamaguchi Tsuyoshi , Seo Yoshiteru 
Published: December 2022

ABSTRACTIn order to investigate the foot manipulation of a clam without a Keber's valve, Calyptogena okutanii was examined by light microscopy, magnetic resonance imaging and computed tomography. The foot chamber was divided into two compartments by a dense muscle fastener zone (FZ) comprising a pedal artery and sinuses in the mid-sagittal plane in between muscles running in the anterior–posterior oblique direction. The distal part of the foot chamber (inflatable fastener bag, IFB) had a loose superficial muscle layer. The proximal part of the foot chamber (visceral reservoir, VR) was covered by a dense superficial muscle layer. The outlet of the VR was connected with the hinge ligament duct, consisting of the hinge ligament, a pair of shells and the pericardium. Based on these anatomical structures, foot extension starts from contraction of muscles in the FZ, so that flow in the FZ is stopped. Then, the superficial muscles of the foot contract, and the pressure of the IFB increases so that the foot can extend. Foot retraction starts from the relaxation of muscles in the FZ so that the hemolymph returns to the VR. The hinge ligament duct allows a constant return flow from the foot chamber to the gills and the heart. The heart rate and the flow in the FZ, which decreased and increased during the foot extension and retraction, respectively, supported this model. In conclusion, the FZ of Calyptogena okutanii could be an alternative to Keber’s valve in Anodonta, playing a similar role.
Significant demotivating factors affecting Saudi EFL students: An investigative study with PYP students
Authors: Alqasham Fahd Hamad 
Published: December 2022

Background: Motivation has long been seen as a deciding factor in the learning of a foreign language and in ensuring success for the learners. As a corollary to this, demotivation adversely affects learning success and negatively influences learning outcomes. The present study examines the factors that negatively affect Saudi EFL learners. Methods: The study subjects are 45 male and 35 female learners, and the data were collected using a 50-item questionnaire. The factors under study are course instructor, course-content and facilities, attitude towards EFL and socio-cultural factors. Data have been analyzed using the SPSS software. Results: Results show that the factors around socio-cultural, and course instructor (M=4.06, 3.67) respectively were the most influential in aggravating the student's demotivation. Furthermore, experience of failure is at play as a moderate factor (M=2.84) whereas the course content and facilities and attitude towards EFL factors, (M=2.57; M=1.83) are perceived as less influential factors in demotivating the EFL students. Findings also show a marginal non-significant difference between male and female participants regarding perceptions of the demotivating factors (males = 5.30, females= 5.70); the difference is not significant, P=, .834. Conclusions: It is presumed that the findings of this study might be helpful for EFL learners and instructors of Saudi Arabia in devising coping strategies to overcome demotivation.
bacto_tracker: a method for single-cell tracking of M. xanthus in dense and multispecies colonies
Authors: Rombouts Sara , Fiche Jean-Bernard , Mignot Tam , Nollmann Marcelo 
Published: December 2022

Cell motility and predation are important for the dynamics of many multi-cellular ecosystems, such as the gut or the soil. Approaches to image cell dynamics in such complex systems are scant, and high-throughput analysis methods to segment and track single-cell behaviors are currently lacking. Here, we addressed these limitations by implementing a fast fluorescence microscopy technique enabling the high-resolution acquisition of cell movement over large areas and long time periods. Next, we applied deep learning to semantically segment two different bacteria species within complex micro-environments . We implemented a method to build single cell traces by combining the cell masks from different time points to follow the dynamics of single cells with high spatial and temporal resolutions and over long periods of time. We applied and validated these methods by characterizing the dynamics of Escherichia coli predation by Myxococcus xanthus.
Achieving good health with a low environmental footprint – A comparison of national indicators
Authors: Mustard Connor , Haines Sir Andrew , Belesova Dr. Kristine , Cousens Professor Simon 
Published: December 2022

Background Integrated metrics that account for resource use and human health are essential to help identify and support human development pathways that safeguard planetary health. We identify countries that achieved the highest levels of health and development at the lowest cost to Earth’s natural capital and report ecological within-country analyses of associations between indicators of environmental sustainability, human health, and development. Methods We used mixed-effects multiple linear regression models of Healthy Life Expectancy (HALE) and Human Capital (HC) related to Ecological Footprint (EF) and CO2 production emissions, controlling for Gini coefficient and population density applied to data of 216 countries from 1991-2016. We performed stratified analyses by country income level and used likelihood-ratio tests to test for interaction. Results Only Jamaica (1991) and Sri Lanka (2016) achieved high HALE at sustainable EF levels. Each 10% increase in EF was associated with 0·20 (95%CI 0·16,0·24) and 0·21 (95%CI 0·19,0·23) increases in HALE and HC respectively; increases in CO2 production emissions were also associated with increased HALE and HC. There was strong evidence for interaction by income level for each model (p<0·016). Stratified analyses showed that in high income nations HALE and HC decreased with increased levels of EF and CO2. Conclusions Countries with high health metrics at sustainable EF levels may offer valuable lessons for sustainable national development policies. Increased environmental footprint and CO2 emissions appear associated with higher levels of human health and development only up to a certain level of income.
Phytoadaptogen reverses the adverse effects of Naftussya bioactive water on dynamic muscle performance in healthy rats
Authors: Fihura Oksana , Ruzhylo Sofiya , Zakalyak Nataliya 
Published: December 2022

Background.. Muscular performance is considered one of the attributes of health and non-specific resistance. Phytoadaptogens occupy an important place in the arsenal of means of increasing non-specific resistance and stress resistance. Many years of research of the Truskavetsian Scientific School of Balneology have demonstrated the adaptogenic properties of the main therapeutic factor of the resort, Naftussya bioactive water, as well as ozokerite and mineral baths. However, in contrast to the beneficial effect of the latter on stress resistance and the neuro-endocrine-immune complex, the effect on the physical performance is ambiguous. The purpose of this study is to test the ability of phytocomposition to prevent the adverse actotropic effect of Naftussya bioactive water at rats. Material and methods. The experimentt have been carried out at 42 female rats. Rats of the control group for 7 days loaded through a tube with tap daily water (2 mL once), while the animals of the other groups received according to a similar scheme daily water with the addition of 0,1 mL of Balm; bioactive Naftussya water per se or with the addition of 0,1 mL of Balm. The day after completion the course of water loads in the animal determined the urinary excretion of 17-ketosteroids, assessed the mineralocorticoid activity (MCA) by the urine K/Na ratio as well as the state of neutrophil phagocytosis by the number of absorbed latex particles. Results. It was found that the weekly use of Naftyssya bioactive water reduces the duration of swimming of rats to exhaustion by 30% compared to the daily water control. Addition of phytoadaptogen to Naftyssya softens its negative actotropic effect by up to -9%, and adding Balsam to daily water prolongs the maximum duration of swimming compared to the control by 11%. A positive correlation of the swimming test with 17-KS excretion and water diuresis was revealed, but a negative correlation with MCA, spontaneous diuresis and neutrophils phagocytosis. Conclusion. Phytoadaptogen reverses the adverse effects of Naftussya bioactive water on dynamic muscle performance in healthy rats by mitigating the decrease in the excretion of 17-ketosteroids and increased mineralocorticoid activity.
Analisis Yuridis Putusan KPPU No. 15/KPPU-I/2019 Terhadap Pengenaan Sanksi Pelaporan Tertulis Jasa Angkutan Udara
Authors: Buana Sandy Ekki Wiratama , Dewi Ratna 
Published: December 2022

Dunia usaha pada akhir tahun 2019 menjadi sorotan publik, ketika lahirnya Putusan KPPU No. 15/KPPU-I/2019. Dimana putusan KPPU tersebut telah memutuskan tujuh maskapai terbukti melakukan pelanggaran persaingan usaha karena dianggap melakukan perjanjian bersama-sama dalam menetapkan harga tiket pesawat. Namun yang menjadi sorotan menurut penulis dan beberapa sumber dalam putusan ini yaitu putusan KPPU yang hanya memberikan sanksi berupa pelaporan saja tanpa mengenakan sanksi denda kepada para pelaku usaha yang terbukti secara sah dan meyakinkan melakukan persaingan usaha tidak sehat, dimana hal tersebut merupakan hal yang cenderung kurang adil dan pasti dalam proses penegakan hukum. Tujuan penelitian ini bertujuan melakukan tinjauan sejauh mana kemanfaatan putusan KPPU yang hanya memberikan sanksi berupa pelaporan saja tanpa mengenakan sanksi denda, dimana hal tersebut merupakan hal yang cenderung kurang adil dan pasti dalam proses penegakan hukum. Penelitian ini menggunakan metode penelitian hukum normatif, dengan menggunakan sumber data sekunder dengan bahan hukum primer dan sekunder. Hasil pembahasan menjelaskan bahwa putusan KPPU tersebut menurut beberapa sumber dan penulis cenderung kurang adil dan pasti dalam proses penegakan hukum. Mengingat ke tujuh maskapai penerbangan tersebut secara sah dan meyakinkan telah melakukan ketentuan pelanggaran Pasal 5 Undang-Undang No. 5 Tahun 1999, namun yang menjadi koreksi harusnya dapat pula dijatuhkan ancaman sanksi denda dalam Pasal 47 ayat (2) huruf g Undang-Undang Nomor 5 Tahun 1999, akan tetapi KPPU tidak menjatuhkan sanksi denda. Kesimpulan dalam penelitian ini terhadap putusan KPPU menurut penulis kurang memberikan efek jera kepada para pelaku usaha yang terbukti secara sah dan meyakinkan melakukan persaingan usaha tidak sehat.
Kata Kunci: Pelaporan tertulis; KPPU; Pelaku Usaha;
Fast shaping control of x ray beams using a closed-loop adaptive bimorph deformable mirror
Authors: Alcock Simon G. , Nistea Ioana-Theodora , Badami Vivek G. , Signorato Riccardo , Fusco Matteo , Hu Lingfei , Wang Hongchang , Sawhney Kawal 
Published: December 2022

High-speed adaptive correction of optics, based on real-time metrology
feedback, has benefitted numerous scientific communities for several
decades. However, it remains a major technological challenge to extend
this concept into the hard x ray regime due to the necessity for
active mirrors with single-digit nanometer height errors relative to a
range of aspheric forms. We have developed a high-resolution,
real-time, closed-loop “adaptive” optical system for
synchrotron and x ray free electron laser (XFEL) applications. After
calibration of the wavefront using x ray speckle scanning, the
wavefront diagnostic was removed from the x ray beam path.
Non-invasive control of the size and shape of the
reflected x ray beam was then demonstrated by driving a
piezoelectric deformable bimorph mirror at

∼

1

H
z

. Continuous feedback was provided by
a 20 kHz direct measurement of the optical surface with
picometer sensitivity using an array of interferometric sensors. This
enabled a non-specialist operator to reproduce a series of pre-defined
x ray wavefronts, including focused or non-Gaussian profiles, such as
flattop intensity or multiple split peaks with controllable separation
and relative amplitude. Such changes can be applied in any order and
in rapid succession without the need for invasive wavefront diagnostic
sensors that block the x ray beam for scientific usage. These
innovations have the potential to profoundly change how x ray focusing
elements are utilized at synchrotron radiation and XFEL sources and
provide unprecedented dynamic control of photon beams to aid
scientific discoveries in a wide range of disciplines.
Exploring the barriers and facilitators to accessing and utilising mental health services in regional, rural, and remote Australia: A scoping review protocol
Authors: Kavanagh Bianca E. , Beks Hannah , Versace Vincent L. , Quirk Shae E. , Williams Lana J. 
Published: December 2022

Introduction
Australians from regional, rural, and remote areas face diverse and complex challenges in accessing and utilising mental health services. Previous research has pointed to a range of individual, community, structural, and systemic barriers at play, however, limited literature has synthesised the knowledge on this topic. Parallel to this, information on the facilitators to accessing and utilising mental health services for this group is not well documented. This protocol describes the methodology to undertake a scoping review, which aims to explore the barriers and facilitators associated with accessing and utilising mental health services in regional, rural, and remote Australia. In addition, the scoping review aims to geographically map the identified barriers and facilitators.

Methods
This protocol is guided by Arksey and O’Malley’s methodological framework. A search strategy will be developed and implemented to identify relevant peer-reviewed and grey literature. Studies will be included if they report on the barriers and/or facilitators associated with accessing and/or utilising mental health services in regional, rural, and remote Australia. Two reviewers will independently screen the data at the title/abstract and full-text stage. One reviewer will extract the relevant data using a predetermined charting form and a second reviewer will validate the included data. A Geographical Information System program will be used to map the location of the studies; locations will be stratified according to the Modified Monash Model and relationships between barriers and facilitators will be analysed. Key findings will be presented in a narrative account and in text, tables, and maps.

Discussion
This scoping review will provide a contemporary account on the barriers and facilitators to accessing and utilising mental health services for regional, rural, and remote Australians. It is anticipated that the results of this scoping review will have national policy relevance and may be useful to healthcare providers.
ART AND THE CREATIVE PROCESS IN EDUCATION FOR ENGINEERS: A STUDY FOCUSED ON UTFPR, BRAZIL
Authors: Auzani Adriana Santos , Silva Levi Leonido , Morgado Elsa Maria Gabriel , Pereira Antonino Manuel de Almeida 
Published: December 2022

Esta pesquisa teve como objetivo estudar a função da arte na promoção da criatividade nos processos formativos dos acadêmicos de engenharia da Universidade Tecnológica Federal do Paraná (UTFPR), enquanto fator de inovação tecnológica. Desenvolvida no âmbito do paradigma construtivista, foi utlizado o método qualitativo, nomeadamente o estudo de caso. A fonte de recolha de dados utlizada foi a entrevista semiestruturada, tendo os respetivos guiões sido desenvolvidos no âmbito da Teoria das Representações Sociais de Serge Moscovici (1978). O campo de estudo foi constituído por 10 estudantes e egressos, por 10 professores, coordenadores e diretores de Ensino e do Campus de Pato Branco, pelo Reitor da universidade e por 4 empresários. A técnica de tratamento de dados utlizada foi a análise de conteúdo. De entre as principais conclusões, saliente-se que os entrevistados entendem que a arte pode contribuir para a melhoria da formação académica do estudante de engenharia uma vez que proporciona novos pontos de vista, promove a criatividade e a inovação. Defendem também que atividades como o teatro podem estimular a capacidade criativa em ambiente universitário dos engenheiros já que permite a promoção da comunicação e expressão, desenvolvimento de um profissional mais completo e favorece a capacidade de abstração. Por último, entendem que a arte e suas diversas expressões estéticas são importantes na formação acadêmica do engenheiro no que diz respeito à criação de projetos inovadores, uma vez que favorece a inspiração, a inovação e a integração em equipes.
Enhancing bilingual resources in third language acquisition: towards pedagogical translanguaging
Authors: Cenoz Jasone , Gorter Durk 
Published: December 2022

Abstract
Third language acquisition in educational contexts is nowadays expanding in monolingual and multilingual contexts. One reason is the mobility of the population that results in an increasing number of home languages that are different from the school languages. Another reason is the spread of the teaching of English as a third language in multilingual school contexts where two other languages are also taught. Third language acquisition is a complex phenomenon that shares many characteristics with second language acquisition but also has some specific differences related to the effect of bilingualism on third language acquisition, multilingual learners’ repertoires and the specific role of metalinguistic awareness in language learning. The aim of this paper is threefold: 1) to look at the potential advantages of bilingualism on L3 considering the great diversity of situations in which an L3 is learned in school contexts; 2) to look at the similarities and differences between second and third language acquisition and 3) to discuss how pedagogical translanguaging can enhance bilingual resources so that L3 learners can develop an optimal use of their resources.
Two case reports of skin vasculitis following the COVID-19 immunization
Authors: Chomičienė Anželika , Černiauskas Kęstutis , Linauskienė Kotryna , Meškauskas Raimundas , Malinauskienė Laura 
Published: December 2022

Abstract
The coronavirus 2019 (COVID-19) disease is now responsible for one of the most challenging and concerning pandemics. Since December 2020, the world has had access to COVID-19 prophylaxis; thus, we encounter adverse events from vaccination more often due to the vast vaccination range. We present two case reports of difficult-to-treat skin vasculitis due to COVID-19 vaccination that were successfully treated in a tertiary-level university hospital. When encountering systemic treatment, resistant skin vasculitis plasmapheresis could be a choice of treatment.
Atrial fibrillation in a patient with lung cancer: a case report
Authors: Shupenina E. Yu. , Vyzhigin D. I. , Gaganov L. E. , Novosel E. O. 
Published: December 2022

Introduction. Cancer remains one of the most common causes of death in the world, second only to cardiovascular diseases. The use of novel chemotherapeutic and targeted agents has significantly improved the prognosis of this group of patients. However, this significantly increased the number of cardiotoxic complications of anticancer therapy, including arrhythmias, in particular atrial fibrillation (AF), which negatively affects the prognosis.Brief description. The purpose of this article was to describe the case of a 64-yearold woman with central right lung lower lobe cancer. Upon admission to the chemotherapy department, the patient was first diagnosed with paroxysmal AF. After chemical cardioversion, the first course of multiagent chemotherapy (MAC) was performed as follows: paclitaxel 280 mg and carboplatin 450 mg, which was complicated by the development of recurrent AF episode. During subsequent MAC courses, arrhythmia episodes regularly occurred. During the next AF episode, the patient was hospitalized at the City Clinical Hospital № 51, where she died despite intensive therapy. Postmortem examination ruled out tumor invasion into the left atrium.Discussion. For the AF development, the patient had prerequisites in the form of a significantly remodeled left atrial myocardium. Chemotherapy agents used as antitumor therapy are characterized by the common development of cardiotoxicity, including variety of arrhythmias. The occurrence of AF episodes coincided with the course of MAC, which suggested its cardiotoxic manifestations. Postmortem examination confirmed the high probability of an association between AF episodes and MAC.Conclusion. The presented case illustrates the difficulties encountered by oncologists and cardiologists in determining the genesis and treatment of complex arrhythmias in cancer patients.
Results of thrombectomy in lower-extremity ischemia in patients with COVID-19 and respiratory failure of different severity
Authors: Polyanskaya E. A. , Sidorova K. V. , Oberina A. P. , Lider R. Yu. , Korotkikh A. V. , Beglaryan Zh. G. , Snigur A. A. , Mukhtorov O. Sh. , Lebedev O. V. , Golokhvastov S. V. , Artyukhov S. V. , Ageev I. I. , Rogova А. А. , Kalichkin I. A. , Kazantsev A. N. 
Published: December 2022

Aim. To analyze the results of thrombectomy in lower-extremity ischemia in patients with coronavirus disease 2019 (COVID-19) and respiratory failure of different severity.Material and methods. This retrospective, cohort, comparative study for the period from May 1, 2020 to March 1, 2022 included 305 patients with acute lower-extremity ischemia and COVID-19. Depending on the type of oxygen support, three groups of patients were formed: group 1 (n=168) — nasal oxygen insufflation; group 2 (n=92) — non-invasive ventilation (NIV); group 3 (n=45) — artificial ventilation (AV). Thrombectomy was carried out according to the standard technique using Fogarty catheters (3F-6F — depending on the vessel size). After the diagnosis was established before and after the start of surgical treatment, all patients received the following therapy: Unfractionated IV heparin infusion at an initial rate of 1000 U/r, adjusted to maintain the activated partial thromboplastin time at 2-3 times the normal value; 2. Oral acetylsalicylic acid 125 mg; 3. Analgesics.Results. Myocardial infarction and ischemic stroke were not detected in the total sample. The highest number of deaths (group 1: 5,3%, n=9; group 2: 72,8%, n=67; group 3: 100%, n=45; p<0,0001), retrombosis (group 1 : 18,4%, n=31; group 2: 69,5%, n=64; group 3: 91,1%, n=41; p<0,0001) and limb amputations (group 1: 9,5%, n=16; group 2: 56,5%, n=52; group 3: 91,1%, n=41; p<0,0001) was recorded in group 3 patients.Conclusion. In patients receiving mechanical ventilation, COVID-19 have more aggressive course, which is expressed in an increase in laboratory para- meters (C-reactive protein, ferritin, interleukin-6, D-dimer), the severity of pneumonia and location of thrombosis in the tibial arteries. Among patients with COVID-19 receiving mechanical ventilation, the greatest number of rethromboses (91,1%), limb amputations (91,1%), and deaths (100%) are noted, which suggests the expediency of abandoning open thrombectomy in favor of anticoagulant/antiplatelet therapy in this cohort of patients. The development of arterial thrombosis in patients with COVID-19 receiving mechanical ventilation is an indicator of a high risk of death. Open thrombectomy in combination with anticoagulant/antiplatelet therapy is most effective in patients on nasal oxygen insufflation or NIV.