bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research on instability characteristics and precursory effect of coal-rock parting-coal structures
Authors: Liu Yang , Wang Jian-Hua , Lu Cai-Ping , Wang Chao , Xie Hua-Dong , Yan Xian-Yang 
Published: July 2022

AbstractThe slip and instability mechanisms of coal-rock parting-coal structures under uniaxial loading conditions were investigated using experiments and case verification. The slip and the corresponding precursors were described by monitoring the displacement, strain, and acoustic emissions (AEs) of coal and rock parting blocks during testing, and the experimental results were verified by analyzing the microseismic (MS) effects during the working face advancing in a coal seam bifurcation area. The main conclusions were as follows: (1) each slip of the discontinuities sandwiched between coal and rock parting produced shear and tensile cracks, but the shear cracks was dominant; (2) for the instability mode that was characterized by low peak stress, high energy release, and a stablebvalue of AE, each slip corresponds to a peak frequency of AE, which can reveal the final instability mode; (3) the sudden drop in the fault total area of AE can be regarded as a precursor for the warning fracture or slip instability of a discontinuity; and (4) the MS events in the coal seam bifurcation area were mainly characterized by a wide frequency and high amplitude, especially near the coal bifurcation line, where there were obvious characteristics of low-frequency shear fracture for the MS events. This study is relevant for the early warning of coal-rock dynamic disasters triggered by the slip, fracture, and instability of coal-rock parting compound structures in coal mines.
Relaxation anisotropy of quantitative MRI parameters in biological tissues
Authors: Hänninen Nina Elina , Liimatainen Timo , Hanni Matti , Gröhn Olli , Nieminen Miika Tapio , Nissi Mikko Johannes 
Published: July 2022

AbstractQuantitative MR relaxation parameters vary in the sensitivity to the orientation of the tissue in the magnetic field. In this study, the orientation dependence of multiple relaxation parameters was assessed in various tissues. Ex vivo samples of each tissue type were prepared either from bovine knee (tendon, cartilage) or mouse (brain, spinal cord, heart, kidney), and imaged at 9.4 T MRI with T1, T2, continuous wave (CW-) T1ρ, adiabatic T1ρ and T2ρ, and Relaxation along fictitious field (RAFF2-4) sequences at five different orientations with respect to the main magnetic field. Relaxation anisotropy of the measured parameters was quantified and compared. The highly ordered collagenous tissues, i.e. cartilage and tendon, presented the highest relaxation anisotropy for T2, CW-T1ρ with spin-lock power < 1 kHz, Ad-T2ρ and RAFF2-4. Maximally anisotropy was 75% in cartilage and 30% in tendon. T1 and adiabatic T1ρ did not exhibit observable anisotropy. In the other measured tissue types, anisotropy was overall less than 10% for all the parameters. The results confirm that highly ordered collagenous tissues have properties that induce very clearly observable relaxation anisotropy, whereas in other tissues the effect is not as prominent. Quantitative comparison of anisotropy of different relaxation parameters highlights the importance of sequence choice and design in MR imaging.
Spatial and temporal patterns of agrometeorological indicators in maize producing provinces of South Africa
Authors: Simanjuntak Christian , Gaiser Thomas , Ahrends Hella Ellen , Srivastava Amit Kumar 
Published: July 2022

AbstractClimate change impacts on maize production in South Africa, i.e., interannual yield variabilities, are still not well understood. This study is based on a recently released reanalysis of climate observations (AgERA5), i.e., temperature, precipitation, solar radiation, and wind speed data. The study assesses climate change effects by quantifying the trend of agrometeorological indicators, their correlation with maize yield, and analyzing their spatiotemporal patterns using Empirical Orthogonal Function. Thereby, the main agrometeorological factors that affected yield variability for the last 31 years (1990/91–2020/21 growing season) in major maize production provinces, namely Free State, KwaZulu-Natal, Mpumalanga, and North West are identified. Results show that there was a significant positive trend in temperature that averages 0.03–0.04 °C per year and 0.02–0.04 °C per growing season. There was a decreasing trend in precipitation in Free State with 0.01 mm per year. Solar radiation did not show a significant trend. Wind speed in Free State increased at a rate of 0.01 ms−1per growing season. Yield variabilities in Free State, Mpumalanga, and North West show a significant positive correlation (r > 0.43) with agrometeorological variables. Yield in KwaZulu-Natal is not influenced by climate factors. The leading mode (50–80% of total variance) of each agrometeorological variable indicates spatially homogenous pattern across the regions. The dipole patterns of the second and the third mode suggest the variabilities of agrometeorological indicators are linked to South Indian high pressure and the warm Agulhas current. The corresponding principal components were mainly associated with strong climate anomalies which are identified as El Niño and La Niña events.
Reliability and validity of the Roche PD Mobile Application for remote monitoring of early Parkinson’s disease
Authors: Lipsmeier Florian , Taylor Kirsten I. , Postuma Ronald B. , Volkova-Volkmar Ekaterina , Kilchenmann Timothy , Mollenhauer Brit , Bamdadian Atieh , Popp Werner L. , Cheng Wei-Yi , Zhang Yan-Ping , Wolf Detlef , Schjodt-Eriksen Jens , Boulay Anne , Svoboda Hanno , Zago Wagner , Pagano Gennaro , Lindemann Michael 
Published: July 2022

AbstractDigital health technologies enable remote and therefore frequent measurement of motor signs, potentially providing reliable and valid estimates of motor sign severity and progression in Parkinson’s disease (PD). The Roche PD Mobile Application v2 was developed to measure bradykinesia, bradyphrenia and speech, tremor, gait and balance. It comprises 10 smartphone active tests (with ½ tests administered daily), as well as daily passive monitoring via a smartphone and smartwatch. It was studied in 316 early-stage PD participants who performed daily active tests at home then carried a smartphone and wore a smartwatch throughout the day for passive monitoring (study NCT03100149). Here, we report baseline data. Adherence was excellent (96.29%). All pre-specified sensor features exhibited good-to-excellent test–retest reliability (median intraclass correlation coefficient = 0.9), and correlated with corresponding Movement Disorder Society–Unified Parkinson's Disease Rating Scale items (rho: 0.12–0.71). These findings demonstrate the preliminary reliability and validity of remote at-home quantification of motor sign severity with the Roche PD Mobile Application v2 in individuals with early PD.
Immigrant background and socioeconomic status are associated with severe COVID-19 requiring intensive care
Authors: Nordberg Per , Jonsson Martin , Hollenberg Jacob , Ringh Mattias , Kiiski Berggren Ritva , Hofmann Robin , Svensson Per 
Published: July 2022

AbstractTo determine whether immigrant background and socioeconomic status were associated with increased risk to develop severe Coronavirus disease 2019 (COVID-19) requiring mechanical ventilation at the intensive care unit and to study their effects on 90-day mortality. Nationwide case–control study with personal-level data from the Swedish Intensive Care register linked with socioeconomic data from Statistics Sweden and comorbidity data from the national patient register. For each case of COVID-19 treated with mechanical ventilation at the intensive care unit (outcome), 10 population controls were matched for age, sex and area of residence. Logistic and Cox regression were used to study the association between the exposure (immigrant background, income and educational level) and 90-day mortality. In total, 4 921 cases and 49 210 controls were matched. In the adjusted model, the risk of severe COVID-19 was highest in individuals born in Asia (Odds ratio [OR] = 2.44, 95% confidence interval [CI] = 2.20–2.69), South America (OR = 2.34, 95% CI = 1.82–2.98) and Africa (OR = 2.11, 95% CI = 1.76–2.50). Post-secondary education was associated with a lower risk of severe COVID-19 (OR = 0.75, CI = 0.69–0.82) as was the highest (vs. lowest) income quintile (OR = 0.87, CI = 0.77–0.97). In the fully adjusted Cox-regression analysis birth region of Africa (OR 1.38, CI = 1.03–1.86) and high income (OR 0.75, CI 0.63–0.89) were associated with 90-day mortality. Immigrant background, educational level and income were independently associated with acquiring severe COVID-19 with need for mechanical ventilation.
Electron–phonon coupling in copper intercalated Bi$$_{2}$$Se$$_{3}$$
Authors: Wiesner Maciej , Koski Kristie , Laitinen Antti , Manninen Juuso , Zyuzin Alexander A. , Hakonen Pertti 
Published: July 2022

AbstractWe report charge and heat transport studies in copper-intercalated topological insulator Bi$$_2$$

2

Se$$_3$$

3

hybrid devices. Measured conductivity shows impact of quantum corrections, electron–electron and electron–phonon interactions. Our shot noise measurements reveal that heat flux displays a crossover between $$T^2$$

T
2

and $$T^4$$

T
4

with the increase of temperature. The results might be explained by a model of inelastic electron scattering on disorder, increasing the role of transverse acoustic phonons in the electron–phonon coupling process.
Sound localization in web-based 3D environments
Authors: Rajguru Chinmay , Brianza Giada , Memoli Gianluca 
Published: July 2022

AbstractSound delivery is a key aspect of immersivity in virtual and augmented reality (VR/AR), with studies hinting at a correlation between users’ ability to locate sounds around them and the ‘feeling of being there’. This is particularly true for WebVR, a method of delivering immersive experiences through a local web browser that has recently captured attention in multiple industries. In WebVR, audio is the main spatial cue. Designers need to select the correct number of sound sources so that users perceive the location of incoming sound correctly. Information on how users localize sound is essential. Sound localization experiments, so far, have been run only in empty spaces or closed rooms, without clear indications for designers in WebVR. Thus, in this study, we investigate sound localization directly through WebVR. To do so, we designed a traditional empty room for training and a city-like virtual environment for testing purposes. In our paper, we also discuss key design parameters, differences in perception for vertical and horizontal directions, the impact of training, and the role of changing virtual environments. In addition, we introduce and test a new sound cue along with the traditional pink noise sound to measure and explore the impact of different sound cues in different environments. The results demonstrate the potential of exploring sound localization using WebVR, and our study will support the development of virtual experiences in human-computer interaction that may be able to reach a large number of participants using a local web browser.
Mechanical properties and failure modes of CRCB specimen under impact loading
Authors: Liu Wenjie , Yang Ke , Dou Litong , Wei Zhen , Chi Xiaolou , Xu Rijie 
Published: July 2022

AbstractTo explore the dynamic mechanical characteristics of CRCB specimens, a separated Hopkinson pressure bar (SHPB) test device combined with ultra-high-speed camera system was used to carry out the impact compression test on CRCB specimens. The stress wave propagation, dynamic stress–strain relationship, dynamic evolution of cracks, energy dissipation law and failure characteristics of the coal–rock combined body in the case of stress waves entering coal from rock were compared and analyzed. The influence of the difference between the rock and the incident bar on the propagation of stress wave gradually weakens with the increase of the impact velocity. The strength stress and peak strain of the CRCB specimens have obvious strain-rate effects. Besides, with increased impact velocity, the incident energy increases linearly, the reflected energy proportion decreases linearly and the absorbed energy proportion change approximately as a power function. Under the same stress wave, as the strength of the rock increases, the failure degree of coal gradually increases, the broken particles gradually transition from massive to powder and the rock mode changes from splitting failure to shear failure. As a result, the average particle size of broken coal blocks decreases, and the fractal dimension of CRCB specimens increases gradually. The research results provide basic research for the control of surrounding rock of roadway under dynamic pressure.
Periodical assessment of four horns of knee meniscus using MR T2 mapping imaging in volunteers before and after amateur marathons
Authors: Zhang Xuesong , Li Jujia , Ren Congcong , Zhang Ping , Zeng Yan , Zhang Ranxu , Wang Ming , Zhou Xiaoyue , Zhao Jian 
Published: July 2022

AbstractTo observe the changes and recovery of T2 values of menisci in amateur marathon participants at different times, and to examine the effect of marathon exercise on meniscal microstructure. Twelve healthy marathon volunteers were recruited continuously, including 5 males and 7 females, with mean (± SD) age of 27.5 ± 5.2 years. The body mass indices (BMIs) ranged from 17.6 to 27.2 kg/m2, with a mean of 21.9 ± 2.5 kg/m2. The 24 knee joints were scanned using a 3 T MR scanner at 1 week before the event, and at 12 h and 2 months after the event. T2 values of the anterior horn of the medial meniscus (MMAH), posterior horn of the medial meniscus (MMPH), anterior horn of the lateral meniscus (LMAH), and posterior horn of the lateral meniscus (LMPH) were measured by drawing the regions of interest (ROIs) on the T2 map images. Wilcoxon sign rank test was used to compare the T2 values between 1 week before and 12 h after the event, and between 1 week before and 2 months after the event in each anatomical region, respectively. The T2 values of the menisci at 12 h after the event were significantly higher (P < 0.05) than those at 1 week before the event. No statistically significant differences in the T2 values of the menisci were found between 2 months after and 1 week before the event (P > 0.05). The T2 values of MMAH, MMPH, LMAH, and LMPH showed a trend of "increasing first and then decreasing" over time, suggesting that the T2 values may reflect meniscal microstructure in amateur marathon runner.
The effect of exposure to MoO3-NP and common bean fertilized by MoO3-NPs on biochemical, hematological, and histopathological parameters in rats
Authors: Shaban Eman E. , Salama Dina M. , Abd El-Aziz Mahmoud E. , Ibrahim Khadiga S. , Nasr Soad M. , Desouky Hassan M. , Elbakry Hagar F. H. 
Published: July 2022

AbstractNanotechnologies has been used to introduce several beneficial tools in the agricultural field. Herein, the effect of molybdenum oxide nanoparticles (MoO3-NPs) was investigated by evaluating the hematological, biochemical, and histopathological parameters in rats orally exposed to MoO3-NPs or fed common beans (CB) fertilized by MoO3-NPs. In the first study, 18 rats were randomly divided into 3 groups: G1 (control group) was given water orally, while G2 and G3 were administered 10 and 40 ppm MoO3-NPs by oral gavage tube, respectively. There was a significant increase in the levels of alanine aminotransferase (ALT), albumin, and total protein; however, there was a a significant decrease in body weight change (BWC), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), creatinine, creatine kinase–MB (CK-MB), thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), and testosterone levels in G3 compared to G1. In the second study, 24 rats were divided into 4 groups: the control (C) group was fed a balanced diet, and three groups were fed on a balanced diet plus 10% CB that was fertilized with 0, 10, and 40 ppm MoO3-NPs, resulting in nCB, CB10, and CB40 groups, respectively. This revealed a significant increase in BWC and total food intake (TFI) but a significant decrease in relative kidney weight in all the CB groups compared to the control group. In CB10 and CB40 groups ALT, LDH, TSH, FT3, and testosterone levels were significantly lower than the respective levels in the control group. We concluded that high doses of MoO3-NPs caused more side effects than low doses in both experiments.
Evaluating changes in growth and pigmentation of Cladosporium cladosporioides and Paecilomyces variotii in response to gamma and ultraviolet irradiation
Authors: Bland Jesse , Gribble Lisa Astuto , Hamel Michael C. , Wright Jeremy B. , Moormann Garrett , Bachand Marlene , Wright Ginger , Bachand George D. 
Published: July 2022

AbstractMelanin-containing fungi (black molds) have the capacity to thrive under extreme environmental conditions such as the elevated radiation levels inside the former Chernobyl reactors. These fungi have been hypothesized to grow toward and use gamma radiation as an energy source, but the literature does not clearly address which energies of the electromagnetic spectrum, if any, positively affect fungal growth. The goal of this work was to characterize the response of non-melanized and melanized fungi to two distinct electromagnetic wavelengths, i.e., ultraviolet (UV) and gamma ray, keeping absorption and other potentially confounding variables constant. Exposure to UV or gamma radiation induced significant changes in fungi pigmentation, but not growth rate ofCladosporium cladosporioidesandPaecilomyces variotii. Specifically, increased pigmentation of both fungi was observed in samples exposed to UV, while decreased pigmentation was observed for gamma-irradiated samples. These results provide new insights into the role of electromagnetic energies on growth of fungi and provide an impetus to examine additional energies and types of radiation to develop a fundamental understanding of this phenomenon.
Tensile strength of nanocrystalline FeCoNi medium-entropy alloy fabricated using electrodeposition
Authors: Watanabe Atsuya , Yamamoto Takahisa , Takigawa Yorinobu 
Published: July 2022

AbstractCrystal-grain refinement is one of the effective approaches to obtaining high-strength materials. A good strength/ductility balance has been reported in fine grains of high- and medium-entropy alloys. However, crystal-grain refinement at the nanometer scale has not been achieved yet. In this study, we used electrodeposition to fabricate 0.2-mm thick equiatomic FeCoNi medium-entropy alloys (MEAs) with 10-nm crystal grains. The nanocrystalline FeCoNi MEAs exhibit the maximum tensile strength of 1.6 GPa, which is the highest reported result to date.
Age-related changes of whole-brain dynamics in spontaneous neuronal coactivations
Authors: Shou Guofa , Yuan Han , Cha Yoon-Hee , Sweeney John A. , Ding Lei 
Published: July 2022

AbstractHuman brains experience whole-brain anatomic and functional changes throughout the lifespan. Age-related whole-brain network changes have been studied with functional magnetic resonance imaging (fMRI) to determine their low-frequency spatial and temporal characteristics. However, little is known about age-related changes in whole-brain fast dynamics at the scale of neuronal events. The present study investigated age-related whole-brain dynamics in resting-state electroencephalography (EEG) signals from 73 healthy participants from 6 to 65 years old via characterizing transient neuronal coactivations at a resolution of tens of milliseconds. These uncovered transient patterns suggest fluctuating brain states at different energy levels of global activations. Our results indicate that with increasing age, shorter lifetimes and more occurrences were observed in the brain states that show the global high activations and more consecutive visits to the global highest-activation brain state. There were also reduced transitional steps during consecutive visits to the global lowest-activation brain state. These age-related effects suggest reduced stability and increased fluctuations when visiting high-energy brain states and with a bias toward staying low-energy brain states. These age-related whole-brain dynamics changes are further supported by changes observed in classic alpha and beta power, suggesting its promising applications in examining the effect of normal healthy brain aging, brain development, and brain disease.
Relationship between subjective well-being and aripiprazole: an [11C]raclopride PET study
Authors: Kim Seoyoung , Ock Elena Younhye , Kwon Jun Soo , Kim Euitae 
Published: July 2022

AbstractThe dopamine blockade by antipsychotics trigger subjective dysphoria. Compared with D2 antagonists, aripiprazole, a D2 partial agonist, was expected to produce a different experience. Indeed, a previous study reported no relationship between the D2 receptor occupancy by aripiprazole and subjective dysphoria, while the D2 receptor occupancy by antagonists was associated with negative subjective experiences. This study revisited the relationship in patients treated with aripiprazole by using an inhibitory Emax model, which enables the individual drug-free binding potential and D2 receptor occupancy to be properly estimated. Eight patients with schizophrenia who have been clinically stable on aripiprazole were enrolled. Assessments including Positive and Negative Syndrome Scale (PANSS) and Subjective Well-being under Neuroleptics Scale (Kv-SWN) were administered. [11C]raclopride PET scan were conducted 2, 26, and 74 h after aripiprazole administration. Regression analysis showed a significant negative association between the D2 receptor occupancy by aripiprazole in the striatum and the Kv-SWN (R2 = 0.55, p = 0.036), but the PANSS total score was not associated with the Kv-SWN (R2 = 0.42, p = 0.080). The negative association between D2 receptor occupancy by aripiprazole and subjective well-being implies that clinicians should find the lowest effective doses of aripiprazole for clinically stable patients to improve their subjective experiences and clinical outcomes.
Pregabalin administration in patients with fibromyalgia: a Bayesian network meta-analysis
Authors: Migliorini Filippo , Maffulli Nicola , Knobe Matthias , Tenze Giacomo , Aljalloud Ali , Colarossi Giorgia 
Published: July 2022

AbstractSeveral studies investigated the effectiveness and the safety of different doses of pregabalin in fibromyalgia. However, the optimal protocol remains controversial. A Bayesian network meta-analysis comparing 300, 450, and 600 mg/daily of pregabalin for fibromyalgia was conducted. The literature search was conducted in January 2022. All the double-blind randomised clinical trials comparing two or more dose protocols of pregabalin for fibromyalgia were accessed. Studies enrolling less than 50 patients were not eligible, nor were those with a length of follow-up shorter than eight weeks. The outcomes of interests were: Fibromyalgia Impact Questionnaire (FIQ), sleep quality, and adverse events. The network meta-analyses were performed using the routine for Bayesian hierarchical random-effects model analysis, with log odd ratio (LOR) and standardized mean difference (SMD) effect measure. Data from 4693 patients (mean age 48.5 years) were retrieved. 93.1% (4370 of 4693 patients) were women. The median follow-up was 14.8 weeks. Pregabalin 450 mg/daily resulted in greater reduction in Fibromyalgia Impact Questionnaire (SMD − 1.83). Pregabalin 600 demonstrated the greatest sleep quality (SMD 0.15). Pregabalin 300 mg/daily evidenced the lowest rate of adverse events (LOR 0.12). The dose of pregabalin must be customised according to patients’ characteristics and main symptoms.