bluuebunny/crossref_metadata_2025_split huggingface dataset:
SILICON APPLICATION AND MYCORRHIZA INOCULATION PROMOTED LEUCAENA LEUCOCEPHALA GROWTH IN A SOIL HIGHLY CONTAMINATED BY MANGANESE
Authors: Carmo Juliette Freitas do , Garcia Kaio Gráculo Vieira , Mendes Filho Paulo Furtado , Pereira Arthur Prudêncio de Araújo , Pinheiro José Israel 
Published: September 2022

ABSTRACT: Arbuscular mycorrhizal fungi (AMF) can increase the acquisition of silicon (Si) and, therefore, alleviate the problems caused by metallic toxicity in plants, but this effect remains poorly understood. The objective was to evaluate the influence of Si application on the growth of Leucaena leucocephala inoculated with AMF (Claroideoglomus etunicatum) in a soil contaminated by manganese (Mn). We exposed plants to increasing levels of Si (0, 100, 200 and 400 mg kg-1) in the soil for 90 days. Intermediate levels of Si and AMF inoculation significantly increased shoot and root dry mass, the number of sheets, root system length and mycorrhizal colonization. The abundance of AMF spores decreased linearly with increasing levels of Si applied to the soil, suggesting a low correlation with mycorrhizal colonization. In addition to the higher Mn contents in the shoots and, mainly, in the roots, the combined application of Si and inoculation with AMF significantly reduced foliar toxicity by more than 40%, when compared to the absence of Si and AMF inoculation. Our results demonstrated a synergistic effect of AMF and Si in improving the growth and tolerance of L. leucocephala plants in soil contaminated by Mn.
Keywords: heavy metals; stress; remediation; AMF; Mn toxicity.

Aplicação de silício e inoculação de micorriza promove crescimento de Leucaena leucocephala em solo altamente contaminado por manganês

RESUMO: Os fungos micorrízicos arbusculares (FMA) podem aumentar a aquisição de silício (Si) e, portanto, amenizar os problemas causados ​​pela toxidez metálica nas plantas, mas esse efeito ainda é pouco conhecido. O objetivo foi avaliar a influência da aplicação de Si no crescimento de Leucaena leucocephala inoculada com FMA (Claroideoglomus etunicatum) em solo contaminado por manganês (Mn). Expusemos as plantas a níveis crescentes de Si (0, 100, 200 e 400 mg kg-1) no solo por 90 dias. Níveis intermediários de Si e inoculação de FMA aumentaram significativamente a massa seca da parte aérea e radicular, o número de folhas, o comprimento do sistema radicular e a colonização micorrízica. A abundância de esporos de FMA diminuiu linearmente com o aumento dos níveis de Si aplicados ao solo, sugerindo uma baixa correlação com a colonização micorrízica. Além dos maiores teores de Mn na parte aérea e, principalmente, nas raízes, a aplicação combinada de Si e inoculação com FMA reduziu significativamente a toxidez foliar em mais de 40%, quando comparada à ausência de Si e inoculação de FMA. Nossos resultados demonstraram um efeito sinérgico de FMA e Si na melhoria do crescimento e tolerância de plantas de L. leucocephala em solo contaminado por Mn.
Palavras-chave: metais pesados; estresse; remediação; FMA; toxidez por Mn.
Систематизація наукових підходів до питання формування кадрового потенціалу Збройних сил України в системі публічного управління
Authors: Біліченко Вадим 
Published: September 2022

У статті обґрунтовано, що існує багато досліджень проблеми формування кадрів оборонного комплексу та кадрів Збройних Сил України. Однак, зазначені дослідження носять поодинокий характер та аналізують різні сфери управління кадрами або управління персоналом. Виокремлено головну мету формування потенціалу Збройних Сил України, зокрема, забезпечення публічної та національної безпеки від зовнішніх та внутрішніх небезпек.
У статті систематизовані наукові підходи до питання формування кадрового потенціалу Збройних Сил України в системі публічного управління. Проведений аналіз дає підстави зазначити, що у науковій літературі аналізують питання кадрового менеджменту Збройний Сил та кадрового менеджменту в українських військових формуваннях. Крім того, сучасні дослідження даної проблематики стосувалися наступного. По-перше, дослідження, спрямовані на удосконалення кадрових технологій щодо формування кадрового потенціалу Збройних Сил, особливо формування кадрового потенціалу управлінських кадрів Збройних Сил України. По-друге, науковці звертають увагу на важливість розвитку кадрового менеджменту Збройних Сил, як сукупності технологій, механізмів, методів та інструментів, які формують, відбирають та удосконалюють кадровий потенціал у сфері Збройних Сил України. По-третє, дослідження присвячені нормативно-правовим механізмам забезпечення кадрового менеджменту Збройних Сил України, у яких звертається увага на неврегульованість кадрових технологій, що формують кадровий потенціал у сфері Збройних Сил України. По-четверте, дослідження, присвячені навчанню та освіти майбутніх фахівців Збройних Сил України, особливо управлінських кадрів. По-п’яте, дослідження, присвячені стратегічному управлінню у системі формування кадрового потенціалу Збройних Сил України. По-шосте, дослідження, присвячені модернізації системи Збройних Сил України з урахуванням міжнародних стандартів та стандартів, встановлених НАТО. По-сьоме, дослідження, спрямовані на аналіз функцій служб (відділів) персоналу та виокремлення шляхів удосконалення даних структурних підрозділів з метою удосконалення діяльності щодо формування кадрового потенціалу Збройних Сил України. Окремо стоять дослідження щодо визначення показників ефективності діяльності служб персоналу в частині формування ефективного кадрового потенціалу Збройних Сил України.
Pengaruh Kombinasi Media Tanam Organik Terhadap Pertumbuhan Cabai Rawit (Capsicum frutescens L.)
Authors: Nasir Yusrianto , Amri  
Published: September 2022

Abstrak
Cabai rawit (Capsicum frutescens L.) merupakan salah satu spesies dari famili solanaceae yang berukuran kecil banyak dimanfaatkan sebagai bumbu dapur, saus dan bahan campur obat-obatan. Cabai rawit memiliki cita rasa pedas yang sangat disukai masyarakat sekitar. Penelitian ini bertujuan untuk mengetahui pengaruh kombinasi media tanam organik (arang sekam, serbuk gergaji dan dedak) terhadap pertumbuhan cabai rawit (Capsicum frutescens L). Pendekatan dalam penelitian ini menggunakan pendekatan kuantitatif. Jenis penelitian eksperimen. Penelitian ini dilaksanakan di Green House Pendidikan Biologi FKIP UM Pare-pare. Teknik pengumpulan data berupa pengamatan langsung dengan mengukur tinggi tanaman, mencacah/menghitung jumlah daun, mengukur panjang akar, volume akar dan menghitung jumlah akar sekunder per 1 cm. Data yang diperoleh dianalisis data menggunakan Uji Analisis Varian (ANOVA). Hasil penelitian menunjukkan bahwa seluruh kombinasi perlakuan menghasilkan perbedaan yang nyata (signifikan) taraf α 0,05 bagi pertumbuhan tanaman, bahwa kombinasi media tanam (tanah, arang sekam, serbuk gergaji dan dedak) berpengaruh pada setiap parameter pengukuran yaitu tinggi tanaman, jumlah daun, panjang akar dan akar sekunder per 1 cm akar primer serta tidak berpengaruh pada volume akar tanaman cabai rawit (Capsicum frutescens L.)
HUBUNGAN PENGGUNAAN INTERNET SEBAGAI MEDIA PEMBELAJARAN DENGAN MINAT DAN HASIL BELAJAR KOGNITIF BIOLOGI SISWA
Authors: Sainab Sainab , Wahid Masyitha , Puspita Sari Eva 
Published: September 2022

Abstrak
Penelitian ini bertujuan untuk mengetahui (1) hubungan antara penggunaan internet sebagai media pembelajaran dengan minat belajar siswa, (2) hubungan antara penggunaan internet sebagai media pembelajaran dengan hasil belajar kognitif biologi, (3) hubungan antara minat belajar dan hasil belajar kognitif biologi siswa kelas XI IPA SMAN 1 Kalukku. Teknik pengambilan sampel dilakukan dengan teknik Cluster Random Sampling sehingga sampel yang digunakan berjumlah 116 orang yang diambil dari masing-masing perwakilan kelas. Data penelitian penggunaan internet sebagai media pembelajaran dengan minat belajar siswa dikumpulkan melalui angket yang dibuat menggunakan google form kemudian disebar secara online melalui grup whatsapp dan hasil belajar kognitif biologi siswa diperoleh dari hasil penilaian oleh guru. Data hasil penelitian diolah dengan menggunakan analisis correlation product moment dengan bantuan SPSS 23. Hasil penelitian menunjukkan bahwa (1) terdapat hubungan yang signifikan antara penggunaan internet sebagai media pembelajaran dengan minat belajar siswa dilihat dari nilai r (0,184) dan nilai signifikansi (0,048) < dari 0,05, (2) terdapat hubungan yang tidak signifikan antara penggunaan internet sebagai media pembelajaran dengan hasil belajar siswa dilihat dari nilai r (0,039) dan nilai signifikansi (0,680) > 0,05, (3) terdapat hubungan yang signifikan antara minat belajar dengan hasil belajar kognitif biologi siswa dilihat dari nilai r (0,811) dan nilai signifikansi (0.000) < dari 0,05.
PAULUS: Revista de Comunicação da FAPCOM
Authors: Paulus Revista 
Published: September 2022

A revista recebe o nome de um dos grandes pensadores do mundo ocidental, Paulo de Tarso. Paulo (Paulus) é o sujeito que pensa o acontecimento e sua relação com a vida. Vive a experiênciade estar num mundo plural, expõe-se a dialogar com os intelectuais de seu tempo, encontrando-se com os de fora, com os diferentes, com as culturas e a fé. um pensador das fronteiras e do universal. Paulo, acima de tudo, foi um amante e buscador ousado da verdade. A Faculdade Paulus de Tecnologia e Comunicação FAPCOM nasce do espírito paulino, porque inspirada no apóstolo Paulo estabelece para si a missão de pensar e ser referência na área da comunicação. A palavra comunicação tornou-se uma das mais conhecidas e repetidas à exaustão, dá o nome aos meios diversos de comunicação e no dia a dia aparece nos diálogos informais. Contudo, vale a pergunta:o que é a comunicação? Realmente as pessoas se comunicam? As tecnologias e seus aparatos podem realmente se comunicar? A revista propõe ser um espaço onde possa se discutir acadêmica e criticamente esse acontecimento fundamental que é a comunicação. O acontecimento da comunicação implica que este reluza nas fronteiras da filosofia e das tecnologias. A filosofia torna-se uma das principais áreas com as quais o acontecimento comunicacional deve dialogar, pois foi ela que pôs primeiro a questão do que é a comunicação. Outra fronteira são as tecnologias que, no mundo contemporâneo, fazem-se presentes em todos os processos da vida humana. O núcleo de atuação da revista estabelece o diálogo entre comunicação, filosofia e tecnologia, com abertura ao que ocorre na sociedade contemporânea e aos seus desafios. A posição assumida pela revista é a da criticidade. Para dar conta de tal desafio de diálogo com o acontecimento comunicacional, publicar-se-á um dossiê sobre o tema central de cada revista, elaboradopor um pesquisador sênior. Trará um artigo internacional de importância acadêmica que ajude a ampliar a discussão central do tema da revista. Os artigos compõem-se de rica produção acadêmica de doutores, pluralizando a visão sobre o assunto tratado. Uma entrevista feita por um pesquisador júnior ajudará a compor uma nova visão, outra perspectiva ao tema estudado. Fundamental será a resenha de obras nacionais ou internacionais de autores queajudem a pensar a comunicação. Por fim, a resenha da melhor tese desenvolvida na área de comunicação ou da filosofia. A FAPCOM e a Paulus Editora unem-se a este espírito e desejam consolidar a sua missão de pensar a comunicação.
PELATIHAN PEMBUATAN MEDIA PEMBELAJARAN FISIKA BERBASIS KOMPUTASI PADA GURU-GURU FISIKA SMA Se-ABEPURA
Authors: Tulak Noper , Bungkang Yusuf 
Published: September 2022

Training on developing physics learning media for high school physics teachers in Abepura and surrounding areas was carried out on 15 and 16 August 2019 at computer laboratory of physics department. The aim of the training is to motivate and improve the ability of teachers to create virtual learning media as alternative physic learning media so as to improve the quality of teaching and physics learning. The method used to support the success of this program is in the form of training, demonstration and practice or tutorial using matlab program. The results of the implementation of service activities felt by the team and the training participants were very satisfying, with indicators of participant activity in each activity process, and participating in training enthusiastically. The training of create physics learning media for senior high school teachers in the community service program that has been implemented is expected to provide understanding and also the ability of teachers to design physics learning media using computers that will have an impact on increasing teaching and learning productivity and professionalism of physics teachers in senior high school. Keywords: learning media, Matlab, physic teachers
The Choice of Translation Strategy in the 21th Century — Based on Comparison of Two Translation Versions of Lun Yu
Authors: Chen Hao 
Published: September 2022

From the Ming and Qing Dynasty onward, Lun Yu has been rendered into virtually all the main languages in the world. Of all English versions of the book, this paper will focus on Ku Hungming’s version and Legge’s version and seek to analyze how can we better coordinate foreignization and domestication to boost the diffusion of the Chinese culture across the world. It is commonly recognized that the two English versions mentioned above are excellent and classical versions of Lun Yu. Yet they adopted totally different translation strategies: Ku Hungming’s version tends to employ the strategy of foreignization while Legge’s version the strategy of domestication. After delving into the pros and cons of the two versions and bearing in mind China’s changing position in the global arena, this paper calls for adjustment of translation strategy so as to help the rest of the world better understand the genuine Chinese culture and increase the recognition of it.
Induction of food-specific IgG by Gene Gun-delivered DNA vaccines
Authors: Smeekens Johanna M. , Kesselring Janelle R. , Frizzell Hannah , Bagley Kenneth C. , Kulis Michael D. 
Published: September 2022

BackgroundShellfish and tree nut allergies are among the most prevalent food allergies, now affecting 2%–3% and 1% of the US population, respectively. Currently, there are no approved therapies for shellfish or tree nut allergies, with strict avoidance being the standard of care. However, oral immunotherapy for peanut allergy and subcutaneous immunotherapy for environmental allergens are efficacious and lead to the production of allergen-specific IgG, which causes suppression of allergen effector cell degranulation. Since allergen-specific IgG is a desired response to alleviate IgE-mediated allergies, we tested transcutaneously-delivered DNA vaccines targeting shellfish and tree nut allergens for their ability to induce antigen-specific IgG, which would have therapeutic potential for food allergies.MethodsWe assessed Gene Gun-delivered DNA vaccines targeting either crustacean shellfish or walnut/pecan allergens, with or without IL-12, in naïve mice. Three strains of mice, BALB/cJ, C3H/HeJ and CC027/GeniUnc, were evaluated for IgG production following vaccination. Vaccines were administered twiceviaGene Gun, three weeks apart and then blood was collected three weeks following the final vaccination.ResultsVaccination with shellfish allergen DNA led to increased shrimp-specific IgG in all three strains, with the highest production in C3H/HeJ from the vaccine alone, whereas the vaccine with IL-12 led to the highest IgG production in BALB/cJ and CC027/GeniUnc mice. Similar IgG production was also induced against lobster and crab allergens. For walnut/pecan vaccines, BALB/cJ and C3H/HeJ mice produced significantly higher walnut- and pecan-specific IgG with the vaccine alone compared to the vaccine with IL-12, while the CC027 mice made significantly higher IgG with the addition of IL-12. Notably, intramuscular administration of the vaccines did not lead to increased antigen-specific IgG production, indicating that Gene Gun administration is a superior delivery modality.ConclusionsOverall, these data demonstrate the utility of DNA vaccines against two lifelong food allergies, shellfish and tree nuts, suggesting their potential as a food allergy therapy in the future.
Silk peptide-hyaluronic acid based nanogels for the enhancement of the topical administration of curcumin
Authors: Niu Jiangxiu , Yuan Ming , Liu Yao , Wang Liye , Tang Zigui , Wang Yihan , Qi Yueheng , Zhang Yansong , Ya Huiyuan , Fan Yanli 
Published: September 2022

The present study focused on the development of Cur-loaded SOHA nanogels (Cur-SHNGs) to enhance the topical administration of Cur. The physiochemical properties of Cur-SHNGs were characterized. Results showed that the morphology of the Cur-SHNGs was spherical, the average size was 171.37 nm with a zeta potential of −13.23 mV. Skin permeation experiments were carried out using the diffusion cell systems. It was found that the skin retention of Cur-SHNGs was significantly improved since it showed the best retention value (0.66 ± 0.17 μg/cm2). In addition, the hematoxylin and eosin staining showed that the Cur-SHNGs improved transdermal drug delivery by altering the skin microstructure. Fluorescence imaging indicated that Cur-SHNGs could effectively deliver the drug to the deeper layers of the skin. Additionally, Cur-SHNGs showed significant analgesic and anti-inflammatory activity with no skin irritation. Taken together, Cur-SHNGs could be effectively used for the topical delivery of therapeutic drugs.
Cadmium fractionation in soils affected by organic matter application: Transfer of cadmium to cacao (Theobroma cacao L.) tissues
Authors: Gutiérrez Eduardo , Chávez Eduardo , Gamage Kasuni H. H. , Argüello David , Galkaduwa Madhubhashini B. , Hettiarachchi Ganga M. 
Published: September 2022

Elevated cadmium (Cd) concentrations in cacao (Theobroma cacao L.) beans have concerned chocolate consumers worldwide because of the potential detrimental human health effects. Compost application on the soil surface could modify the labile Cd in soils and yet it could enhance Cd bound to humic and fulvic acids, forming an organo-metallic complex that could reduce the availability of Cd to plants. This study investigated the effect of surface compost applications at two rates, the chemistry and fractionation of Cd at two soil depths, and the relationship of these soil Cd pools with plant uptake. The research was carried out on four Ecuadorian cacao farms. The compost was applied at 6.25 Mg·ha−1 (low) and 12.5 Mg·ha−1 (high) per annum. There was also a control treatment with no compost application. Soil samples were collected at two depths, surface (0–5 cm) and below surface (5–20 cm). Leaf samples and cacao pots were collected from each treatment. Soil Cd was fractionated into five operational pools. Additionally, the Cd-bound to fulvic acids and humic acids in soils were extracted separately. The EDTA-extractable fraction showed the highest concentration of Cd at both depths. Cadmium bound to fulvic acids was higher in compost-applied soils than in the control (p &lt; 0.05) in all farms. Leaf and bean-Cd were negative and significantly correlated with the Cd extracted by EDTA, NaOH, HNO3, and FA-Cd pools. The mobility of Cd in soils cultivated with cacao, based on plant uptake, was strongly associated with the soils’ chemical characteristics, especially pH and SOC. The surface application of organic matter facilitates the redistribution of Cd in soil fractions, mainly in EDTA-, NaOH-, and HNO3-extractable fractions, suggesting a reduction in Cd soil–plant transfer via adsorption or complexation processes. Apparently, the application of high-quality compost, i.e., high FA content, could aid in mitigating Cd contamination in cacao orchards. Experiments on perennial crops merit a longer evaluation time to better assess the changes in plant-Cd.
Transcriptome profiles of fatty acid metabolism-related genes and immune infiltrates identify hot tumors for immunotherapy in cutaneous melanoma
Authors: Dong Yunxian , Zhao Zirui , Simayi Maijimi , Chen Chufen , Xu Zhongye , Lv Dongming , Tang Bing 
Published: September 2022

Background: Immunotherapy with checkpoint inhibitors usually has a low response rate in some cutaneous melanoma (CM) cases due to its cold nature. Hence, identification of hot tumors is important to improve the immunotherapeutic efficacy and prognoses of CMs.Methods: Fatty acid (FA) metabolism-related genes were extracted from the Gene Set Enrichment Analysis and used in the non-negative matrix factorization (NMF), copy number variation frequency, tumor mutation burden (TMB), and immune-related analyses, such as immunophenoscore (IPS). We generate a risk model and a nomogram for predicting patient prognoses and predicted the potential drugs for therapies using the Connectivity Map. Moreover, the NMF and the risk model were validated in a cohort of cases in the GSE65904 and GSE54467. At last, immunohistochemistry (IHC) was used for further validation.Results: Based on the NMF of 11 FA metabolism-related DEGs, CM cases were stratified into two clusters. Cluster 2 cases had the characteristics of a hot tumor with higher immune infiltration levels, higher immune checkpoint (IC) molecules expression levels, higher TMB, and more sensitivity to immunotherapy and more potential immunotherapeutic drugs and were identified as hot tumors for immunotherapy. The risk model and nomogram displayed excellent predictor values. In addition, there were more small potential molecule drugs for therapies of CM patients, such as ambroxol. In immunohistochemistry (IHC), we could find that expression of PLA2G2D, ACOXL, and KMO was upregulated in CM tissues, while the expression of IL4I1, BBOX1, and CIDEA was reversed or not detected.Conclusion: The transcriptome profiles of FA metabolism-related genes were effective for distinguishing CM into hot–cold tumors. Our findings may be valuable for development of effective immunotherapy for CM patients and for proposing new therapy strategies.
Mild cognitive impairment is associated with low copy number of ribosomal genes in the genomes of elderly people
Authors: Veiko Natalia N. , Ershova Elizaveta S. , Veiko Roman V. , Umriukhin Pavel E. , Kurmyshev Marat V. , Kostyuk Georg P. , Kutsev Sergey I. , Kostyuk Svetlana V. 
Published: September 2022

Introduction: Mild cognitive impairments (MCI) accompanying aging are associated with oxidative stress. The ability of cells to respond to stress is determined by the protein synthesis level, which depends on the ribosomes number. Ribosomal deficit was documented in MCI. The number of ribosomes depends, together with other factors, on the number of ribosomal genes copies. We hypothesized that MCI is associated with low rDNA CN in the elderly person genome.Materials and Methods: rDNA CN and the telomere repeat (TR) content were determined in the DNA of peripheral blood leukocytes of 93 elderly people (61–91 years old) with MCI and 365 healthy volunteers (16–91 years old). The method of non-radioactive quantitative hybridization of DNA with biotinylated DNA probes was used for the analysis.Results: In the MCI group, rDNA CN (mean 329 ± 60; median 314 copies, n = 93) was significantly reduced (p &lt; 10–15) compared to controls of the same age with preserved cognitive functions (mean 412 ± 79; median 401 copies, n = 168) and younger (16–60 years) control group (mean 426 ± 109; median 416 copies, n = 197). MCI is also associated with a decrease in TR DNA content. There is no correlation between the content of rDNA and TR in DNA, however, in the group of DNA samples with rDNA CN &gt; 540, TR content range was significantly narrowed compared to the rest of the sample.Conclusion: Mild cognitive impairment is associated with low ribosomal genes copies in the elderly people genomes. A low level of rDNA CN may be one of the causes of ribosomal deficit that was documented in MCI. The potential possibilities of using the rDNA CN indicator as a prognostic marker characterizing human life expectancy are discussed.