bluuebunny/crossref_metadata_2025_split huggingface dataset:
WITHDRAWN: Low Leakage Variation SRAM Cell with Improved Stability for IOT Applications
Authors: Rawat Ram Murti , Kumar Vinod 
Published: November 2022

Abstract
The typical memory for very large scale integrated (VLSI) circuits has traditionally been static random access memory (SRAM). This is so because SRAM is a speedier technology than the ones that were previously mentioned. SRAM, however, has a high power consumption rate. Due to its importance in the memory architecture, it is crucial to lower the power consumption of SRAM cells. This literature review's major goal is to provide innovative and effective strategies for creating low power SRAM cells. This study provides several circuit topologies and methodologies to compute stability, leakage current, delay, and power, as well as novel techniques for designing SRAM cells based on eight transistors (8T). The static random access memory (SRAM) is frequently chosen over dynamic random access memory (DRAM) due to faster speed and lower power consumption. It is named static since no modification or action, i.e. refreshing, is required to maintain the data intact. The leakage current in SRAM, however, frequently rises and impairs its performance when technology nodes are scaled down. Voltage scaling, which also impacts the stability and latency of SRAM, is chosen as a solution to this problem. In this study, a separate (isolated) read port is employed to increase read stability while a negative bit-line (NBL) write aid circuit is used to improve write capability. In terms of write static noise margin (WSNM), write latency, read static noise margin (RSNM), and other metrics, the suggested design has been compared to state-of-the-art work. The following is how the paper is divided into sections: 1. Introduction. Section 2 describes related work. The suggested work is in section 3. Results and discussion are included in section 4 and section 5 Conclusions.
Changes of spinal flexion angle while toileting with smartphone using
Authors: Luo Ziyi , Li Baojian , Liu Ying , Liu Lu , Li Yang , Liu Yanyan , Duan Huimin , Xiao Yu , Fu Liping , Zeng Hui , Liu Gang 
Published: November 2022

Abstract
Background
The aim of this study was to quantify spinal flexion when using a smartphone while toileting.
Methods
Thirty participants were required to measure the spinal flexion angles in the Sagittal Plane when carrying out both hands, one hand and no smartphone using while toileting for 10 minutes. Five separate inertial motion sensors were placed and installed individually upon the partcipants' forehead, cervical, thoracic, and lumbar spinal regions. All data were statistically analyzed by SPSS 26.0 software.
Results
Result showed spinal and cervical flexion angle were significantly greater ( p < 0.05) on both and one hand smartphone using. There was no significant difference of the increased flexion angle of each region of the spine when using the mobile phone with both hands and one hand for 10 minutes (P > 0.05). Regression analysis showed a statistically significant correlation between the spinal flexion angle and time on no smartphone using(r = 0.747,p < 0.001) task. Regression analysis showed a statistically significant correlation between the spinal flexion angle and time on both hands smartphone using(r = 0.793,p < 0.001) task.Regression analysis showed a statistically significant correlation between the spinal flexion angle and time on one hand smartphone using(r = 0.855,p < 0.001) task.When sitting on the toilet and using the smartphone with both hands and one hand, the spine flexion angle changes exponentially with time to a certain extent. Within ten minutes, it will first increase rapidly and then gradually flatten with the increase of time.When using the smartphone with both hands, the flexion angle of the spine enters a stable state faster than when using the mobile phone with one hand.
Conclusion
Study revealed using smartphone while toileting would pose a larger load to the spine, particularly to cervical vertebrae musculature. The flexion angle of the spine will gradually increase even when not using smartphone while toileting. Therefore, we suggested not using smartphone and shorten the time on toileting in order to prevent large spinal load.
Knowledge of 3rd Year Degree Nursing Students at a University Regarding Contributing Factors of Neonatal Sepsis, Windhoek, Namibia.
Authors: Kadhila Joseph Galukeni , Gaingos Manuella 
Published: November 2022

Abstract
Introduction: Neonatal Sepsis is the blood infection that occurs in an infant younger than 90 days old. Early onset is seen in the first week of life and late onset sepsis occurs after 1 week through 3 months of age. The symptoms are breathing problems, low blood sugar, reduced body movements, vomiting, decreased bowel movements, jaundice and the possible complications are disability and. Neonatal sepsis is a public health problem that causes death or disability in infant younger than 90 days old unless proper antibiotic treatment is given on time.
Methods: A self-administered questionnaire was distributed to 73 3rdyear nursing students from UNAM main campus. The study had a 100% response rate, with most of the 3rdyear nursing students being female, and also not being enrolled in practicing nursing before.
Results: The study found that that most of the 3rdyear nursing students had sound knowledge of the factors contributing to neonatal sepsis as the study found that most students were aware that prematurity and low-birth-weight were contributing factors of neonatal sepsis. The 3rdyear nursing students were also knowledgeable that pre-mature rapture of the membranes is one of the contributing factors of neonatal sepsis, and that babies with low-birth-weight were at risk of being infected with neonatal sepsis. Findings also show that 3rdyear nursing students had sound knowledge of when neonatal sepsis occurs and when to diagnose it.
Conclusion: The study concluded that concluded that 3rd year nursing students at UNAM main campus has good knowledge about the contributing factors of neonatal sepsis. However, the 3rdyear nursing students still need to improve their knowledge on the management practices of neonatal sepsis as some of the students chose to remain neutral at questions that assessed the management practices of neonatal sepsis. Recommendations were made based on the findings.
Vibration reduction and bifurcations properties of spaceborne flywheel system using nonlinear energy sink with Euler-buckled beams
Authors: Liu Haiping , Zhang Jun , Shen Dashan , Xiao Kaili 
Published: November 2022

Abstract
This study develops a new class of Euler-buckled beam nonlinear energy sink (EBNES) with three configurations, which is expected to attenuate the disturbance effects and further enhance vibration suppression under launching and on-orbit loads simultaneously. The effects of arrangements on amplitude-frequency responses of the primary system are analyzed, and the approximate solutions are verified by numerical results. Comparisons with results exhibit that the EBNES-I is much more effective with significantly enhanced vibration reduction performance and stability in a broad frequency range. Furthermore, a two-degree-of-freedom dynamic model of the flywheel system, which integrates the EBNES-I and the satellite platform, is established. The vibration attenuation and bifurcation behaviors of the proposed EBNES-I is investigated, and the efficiency of the proposed EBNES-I in vibration reduction of the flywheel is compared to that of a cubic-stiffness NES. It is found that the EBNES-I exhibits a good vibration reduction performance on the dynamic responses of the flywheel system in launching and on-orbit stage simultaneously. Additionally, the bifurcations of the system are studied in order to find influences of gravity, excitation amplitudes and geometrical parameters on the stability of the EBNES. Calculation results provide suitable conditions for occurrence of the SN and Hopf bifurcations.
Effects of cardiorespiratory fitness and body mass index on cardiometabolic risk factors in schoolchildren
Authors: Bagatini Natália Carvalho , Pinho Carolina Dertzbocher Feil , Leites Gabriela Tomedi , Voser Rogério da Cunha , Gaya Anelise Reis , Cunha Giovani dos Santos 
Published: November 2022

Abstract
Introduction: High levels of physical fitness established in childhood and adolescence have been associated with positive effects on cardiometabolic risk factors (CMRF), persisting into adulthood. Conversely, high rates of a sedentary lifestyle, overweight, and obesity in this period have been considered a public health problem, because these conditions tend to worsen in adulthood, increasing the incidence of chronic diseases, deterioration of CMRF, and consequently increasing comorbidities and mortality.
Objective: To verify the effect of cardiorespiratory fitness (CRF) and body mass index (BMI) on CMRF in children and adolescents.
Methods: The sample was composed of 49 schoolchildren of both sexes aged 10-17 years. Anthropometric assessments, CRF test, muscle strength test, and blood pressure (BP) measurement were performed. Participants were allocated into groups according to BMI (eutrophic, overweight, obese) and CRF (low-fit, normal-fit, and high-fit) levels.
Results: Obese individuals had lower CRF values compared to eutrophic and overweight groups. The cardiometabolic risk (CMRP) was significantly higher in the obese group when compared to the normal group, but without difference in relation to the overweight group. The Hight-fit group had lower CMRF values compared to the Low-fit group.
Conclusions: Higher BMI and CRF values had negative and positive effects on CMRF and CMRP in schoolchildren, respectively. Overweight or obese schoolchildren with low fitness levels constitute an unfavorable cardiometabolic health risk profile.
Surviving The Cold: A Case Study on Competition Between Native Lepomis macrochirus and Invasive Herichthys cyanoguttatus for Overwinter Habitat Use
Authors: Lorenz O. T. , Coghill L. M. , Smith P. , Riccobono S. A. , Exum A. 
Published: November 2022

Abstract
Invasive species management can be challenging or even impossible, especially in aquatic environments. To determine if the tropical origins of an invasive species affected where it could be targeted, we constructed a study to compare winter behavior of a tropical, invasive species to a temperate weather, native species in Louisiana. The winter activity and cold tolerance of ten invasive Rio Grande Cichlids, Herichthys cyanoguttatus and ten native bluegill, Lepomis macrochirus was observed using an outdoor pond with a dual antenna PIT tag array and an artificial culvert created inside of the pond. All fishes had PIT tags injected into their lateral musculature. Both species were active at temperatures below 10°C and all twenty fish survived temperatures as low as 7°C. Even though the invasive H. cyanoguttatus is a member of a tropical family of fishes, activity and even feeding behavior of both species was similar up to 13°C; but H. cyanoguttatus individuals were more active than L. macrochirus at higher temperatures. Both species appeared to use the culvert during cold fronts, demonstrating that the behavior of both species during cold weather were remarkably similar. This study illustrates the thermal tolerance abilities of H. cyanoguttatus in New Orleans and also demonstrates their potential for invading other cold-water habitats.
Significance Statement
This article is the first to investigate the simultaneous examination of overwintering behavior of a temperate native species of fish and an invasive tropical species of fish. Its application to invasive species management has unique usefulness not previously published. It is also unique in its examination of overwintering fish behavior in general, using a mesocosm PIT tag array.
Neural Network-Based Output Tracking Control of High-Order Nonlinear Systems with DoS Attacks and Perturbations
Authors: Jin Xiaozheng , Yan Bingheng , Chi Jing , Wu Xiaoming , Deng Chao 
Published: November 2022

Abstract
This paper focuses on the output feedback tracking control of a high-order nonlinear system with denial-of-service (DoS) attacks and exogenous perturbations. A novel neural network (NN)based state estimator is employed to observe the system states during DoS attacks. New nonlinear filters with adaptive regulation are developed to reduce the conservatism of estimator designs and eliminate the impact of unexpected factors such as perturbations and NN approximation errors. Constituting with filtering operation and backstepping control technique, an NN-based secure controller is constructed to suppress the influences of nonlinearities and DoS attacks. The semiglobally uniformly ultimately bounded output tracking results are established by Lyapunov functions on the basis of the estimation and control signals in the cases of DoS attacks, nonlinearities, and perturbations. Comparative results are provided to validate the efficiency of the developed NN-based observation and secure control strategies of a nonlinear system.
Knowledge of crisis prevention strategies are highly effective, whereas vulnerability scores may elicit Addison’s disease crises
Authors: Ross Ian Louiss , Anderson Michelle Moya , Demeke Belene , Minnnie Elza Louise , Henry Michelle 
Published: November 2022

Abstract
Objective: The knowledge in patients with Addison’s disease (AD) to prevent an adrenal crisis and the degree to which patients feel vulnerable.
Design: Telephonic interview of patients with AD in 47 patients, assessing knowledge of prevention of a crisis and vulnerability using a vulnerability scale.
Methods: Knowledge of adrenal crisis (AC) and vulnerability score completed. Patients were compared based on having had a crisis or not. Factors associated with AC and the impact of knowledge, vulnerability were determined.
Results: (64%) had an adrenal crisis in the previous five years, compared with 34% who never had a crisis. Crisis was associated with poorer knowledge prevention of an AC, especially having a cold (31.2% vs 71%; p=0.002) fever (44.7% vs 90.3%; p<0.001) infection (50% vs 93.5%; p<0.001) vomiting (50% vs 80.6%; p=0.007), and diarrhoea (37.5% vs 71%; p<0.001), respectively. The median proportion with vulnerability for each question was 41.5%. Disease duration was negatively correlated with vulnerability; (r=-0.426, p=0.003). Number of comorbidities was correlated with vulnerability (r=0.290, p=0.048). A negative correlation between knowledge score and number of crises in the previous five years (r=-0.530, p<0.001). Logistic regressions showed the only predictor for a crisis in the past year or past 5 years was patients’ knowledge (p<0.001). Predictors of knowledge were younger patients, more comorbidities, patients who had AC, scored higher on vulnerability questionnaire. Variables accounted for 52% of the variance (F=9.751, p<0.001).
Conclusions: Education is critical in preventing AC, specifically cold, fever, infection, vomiting and diarrhoea. Health-care providers should provide psychological support, considering significant vulnerability burden.
A fatal case of cytomegalovirus pneumonia with Aspergillus infection in a non-transplanted patient : A case report
Authors: Huang Kun-lun 
Published: November 2022

Abstract
Introduction: Cytomegalovirus (CMV) is a common disease in transplant patients who are also susceptible to secondary bacterial or fungal infections. However, co-infection in non-transplant patients is rare and often complicates diagnosis and treatment.
Patient concerns: The patient was an older adult woman with poor immune function but was not a transplant patient.
Diagnosis: The patient visited the doctor because of fever and shortness of breath for 1 day and was diagnosed with CMV combined with fungal pneumonia.
Interventions: Treatment with ceftriaxone + human immunoglobulin + voriconazole
Outcomes: The patient’s condition continued to deteriorate, and she eventually died of myocardial infarction.
Conclusion: In immunocompromised patients, combination therapy may be a key factor in improving prognosis, in addition to early detection of coinfection.
The prognostic value of the seventh edition of the AJCC staging system for nasopharyngeal carcinoma in China
Authors: Liu Ying , Qiu Yanbing , Li Xiayu , Huang Donghai , Zou Guoying , Fan Songqing , Shi Lei , Jiang Su , Zhou Qing , Feng Ranran , Guo Yilin , Li Xiaoxu , Zhu Yan , Xiang Bo , Zeng Zhaoyang , Xiong Wei , Li Guiyuan , Zhang Wenling 
Published: November 2022

Abstract
The 7th edition of the International Union against Cancer/American Joint Committee on Cancer (UICC/AJCC) manual defines new classification rules for nasopharyngeal carcinoma (NPC). The study was conducted to assess its effectiveness in predicting the prognosis of patients in Hunan Province, China. Between January 2001 and December 2004, 84 primary NPC patients with detailed clinical information were collected. We retrospectively analyzed the follow-up data of these patients in Sep 2007, July 2009, July 2010, Dec 2013, and Nov 2020. The 7th edition of the AJCC system creates subgroups (stages I to IV) that are assigned to 10 (11.9%), 31 (36.9%), 27 (32.2%), and 16 (19.0%) patients, respectively. The 7th edition of the AJCC system showed highly significant differences in gender for DFS. In the 7th version of the AJCC the overall stages, T classifications, and N classification showed a significant correlation with OS and disease-free survival (DFS). Multivariate analysis showed that T classification and N classification were independently significant prognostic factors for DFS and OS with 6-years. In conclusion, the 7th edition of the AJCC system for NPC is prognostically useful for patients from Hunan Province.
Analysis of Anterior Permanent Dentition in Chinese population via Cone-beam Computed Tomography
Authors: CHEN YU , Lu Bingtai , Dai Yu , You Yuehua , Wu Bin , Yan Zhengbin 
Published: November 2022

Abstract
Purpose: Investigation of roots and canals is crucial in clinical assessment and treatment. Morphologies such as root length, cemento-enamel junction curvature (CEJ-C), root furcation and canal variations are important factors yet remain to be discussed in depth.
Methods: In this retrospective study, we look into 4309 anterior teeth from 401 patients via cone-beam computed tomography (CBCT) in Chinese population, attempting to summarize the morphological characteristics of maxillary and mandibular anterior teeth.
Results: Maxillary and mandibular canines are observed with elevated root length compared with corresponding incisors (p<.0001), while those of mandibular central and lateral incisor varied with significant difference (p<.0001). The CEJ-C reveals significant increasement around incisors than canines in maxilla (p<.0001). Root furcation is detected in mandibular canines and lateral incisors. Moreover, all types of Vertucci’s classification are noticed with two other new types.
Conclusions: The current findings help to optimize the root morphological understanding of Chinese population especially in endodontics. Moreover, CEJ-C facilitates clinical aesthetic interpretation and treatment in implantology and prosthodontic. However, further study should be carried out to investigate morphologies of posterior dentition.
Dynamic Educational Recommender System Based on Improved LSTM Neural Network
Authors: Yazdi Hadis Ahmadian , Mahdavi Seyyed Javad Seyyed , Kheirabadi Maryam 
Published: November 2022

Abstract
Virtual learning environments have become widespread in today's society to avoid time and space constraints and to share high-quality learning resources. In the process of human-computer interaction, student behaviors are recorded instantly. This article aims to design an educational recommendation system according to the individual's interests in educational resources, which is evaluated based on clicking or downloading the source and the score given to that source by the user. In online tutorials, in addition to the problem of choosing the right source, we face the challenge of how to be aware of diversity in users' preferences and tastes, especially their short-term interests in the near future, at the beginning of a session. We assume that the user's interests consist of two parts: 1) the user's long-term interests, which include the user's constant interests based on the history of the user's dynamic activities, and 2) the user's short-term interests, which indicate the user's current interests. Due to the use of Bilstm networks and their gradual learning feature, the proposed model supports learners' behavioral changes, with an average accuracy of 0.9978 and an error of 0.0051 offers more appropriate recommendations than similar articles.
Biofilm formation of Pseudomonas aeruginosa in spaceflight is minimized on Lubricant Impregnated Surfaces
Authors: Zea Luis , Flores Pamela , McBride Samantha , Galazka Jonathan , Varanasi Kripa 
Published: November 2022

AbstractThe undesirable, yet inevitable, presence of bacterial biofilms in spacecraft poses a risk to the proper functioning of systems and to astronauts’ health. To mitigate the risks that arise from them, it is important to understand biofilms’ behavior in microgravity. As part of the Space Biofilms project, biofilms ofPseudomonas aeruginosawere grown in spaceflight over material surfaces. Stainless Steel 316 (SS316) and passivated SS316 were tested for their relevance as spaceflight hardware components, while a lubricant impregnated surface (LIS) was tested as potential biofilm control strategy. The morphology and gene expression of biofilms were characterized. Biofilms in microgravity were less robust than on Earth. LIS strongly inhibited biofilm formation compared to SS. Furthermore, this effect was even greater in spaceflight than on Earth, making LIS a promising option for spacecraft use. Transcriptomic profiles for the different conditions are presented, and potential mechanisms of biofilm reduction on LIS are discussed.
Tacrolimus reverses pemphigus vulgaris serum-enhanced expression of desmoglein in HaCaT cells via inhibition of heat shock protein-27 phosphorylation
Authors: Xie Zhimin , Li Qingqing , Dai Xiangnong , Ye Xingdong 
Published: November 2022

Abstract
Background: Glucocorticoids are the first-line treatment for Pemphigus vulgaris (PV), but its serious side effects can be life-threatening for PV patients. Tacrolimus (FK506) has been reported to have an adjuvant treatment effect against PV. However, the mechanism underlying the inhibitory effect of FK506 on PV-IgG-induced acantholysis is unclear.
Objective: The objective of this study was to explore the effect of FK506 on desmoglein (Dsg) expression and cell adhesion in an immortalized human keratinocyte cell line (HaCaT cells) stimulated with PV sera.
Methods: A cell culture model of PV was established by stimulating HaCaT cells with 5% PV sera with or without FK506 and clobetasol propionate (CP) treatment. The effects of PV sera on intercellular junctions and protein levels of p38 mitogen-activated protein kinase (p38MAPK), heat shock protein 27 (HSP27), and Dsg were assayed using western blot analysis, immunofluorescence staining, and a keratinocyte dissociation assay.
Results: PV sera-induced downregulation of Dsg3 was observed in HaCaT cells and was blocked by FK506 and/or CP. Immunofluorescence staining revealed that linear deposits of Dsg3 on the surface of HaCaT cells in the PV sera group disappeared and were replaced by granular and agglomerated fluorescent particles on the cell surface; however, this effect was reversed by FK506 and/or CP treatment. Furthermore, cell dissociation assays showed that FK506 alone or in combination with CP increased cell adhesion in HaCaT cells and ameliorated loss of cell adhesion induced by PV sera. Additionally, FK506 noticeably decreased the PV serum-induced phosphorylation of HSP 27, but had no effect on p38MAPK phosphorylation.
Conclusion: FK506 reverses PV-IgG induced-Dsg depletion and desmosomal dissociation in HaCaT cells, and this effect may be obtained by inhibiting HSP27 phosphorylation.