bluuebunny/crossref_metadata_2025_split huggingface dataset:
Expressions and clinical significance of interleukin-1β and cyclooxygenase-2 in serum and synovia of patients with gouty arthritis
Authors: Chen Gang , Xiang Chenghao , Zou Li , Xu Li , Cheng Zhitao , Liu Yong 
Published: February 2022

Abstract

Background: To explore the expressions and clinical significance of interleukin-1β (IL-1β) and cyclooxygenase-2 (COX-2) in serum and synovia of patients with gouty arthritis (GA).

Materials and Methods: A total of 110 GA patients hospitalized from January 2016 to September 2019 were selected as observation group, with 55 at remission stage (observation group I) and 55 at acute attack stage (observation group II). Another 55 healthy volunteers were selected as control group. The correlations of IL-1β and COX-2 with uric acid (UA) were explored by Spearman’s analysis. IL-1β and COX-2 expression levels were compared at different time points after treatment.

Results: IL-1β, COX-2 and UA levels of patients were significantly higher in observation group I and II than those in the control group, and higher in the observation group II than those in observation group I. IL-1β and COX-2 were positively correlated with UA (P<0.05). ROC curve analysis showed that the optimal cut-off values of IL-1β and COX-2 for predicting GA were 18.23 and 9.12 pg/mL, and AUC values were 0.702 and 0.714 (P<0.001), respectively. On admission and after treatment for 3, 7, and 10 days, IL-1β and COX-2 levels of observation group II significantly exceeded those of observation group I (P<0.05). Compared with the efficacy group, after treatment for 14 days, IL-1β and COX-2 levels in serum and synovia significantly increased in the non-efficacy group (P<0.05).

Conclusion: IL-1β and COX-2 levels in serum and synovia of GA patients are evidently higher than those in the control group, which rise with the aggravation of disease.
An insight into the fecal microbiota composition in Romanian patients with ankylosing spondylitis using high-throughput 16S rRNA gene amplicon sequencing
Authors: Oprea Mihaela , Cristea Daniela , Dinu Sorin , Ciontea Simona Adriana , Bojinca Violeta Claudia , Predeteanu Denisa , Balanescu Andra Rodica , Usein Codruta Romanita 
Published: February 2022

Abstract

Introduction. Application of next-generation sequencing technology generated a massive amount of information on the gut microbiome composition used to understand its role in the healthy state and in various diseases. We aimed to provide information on the gut microbiota composition of Romanian subjects diagnosed with ankylosing spondylitis, an immune-mediated arthropathy linked to a genetic predisposition and gut dysbiosis.

Methods. Stool samples collected from 25 patients with ankylosing spondylitis and 16 healthy controls were investigated using high-throughput DNA sequencing of 16S rRNA amplicons from seven different hypervariable regions and Ion Torrent PGM instrument. Microbial composition of metagenomic data was analyzed with QIIME software and differential abundance analysis of taxa encompassed linear discriminant analysis effect size (LEfSe).

Results. Overall, 14 phyla, 114 families, 114 genera, and 275 species were identified across the 41 samples, the aggregated data revealing as most abundant the phyla Bacteroidetes, Firmicutes, and Proteobacteria, the families Bacteroidaceae, Prevotellaceae, and Ruminococcaceae, the genera Bacteroides, Prevotella, and Faecalibacterium, and Prevotella copri species. Using various cutoffs for abundance and prevalence, core taxonomic members were identified which in general were shared between the patients and controls. However, evidence was gained that the diversity in the microbiomes from the former cohort was lower than for controls and that certain taxa had significantly different abundance between the two groups.

Conclusion. This study allowed an informative high-throughput 16S rRNA profiling of the gut microbiota needed to identify microbiome signatures of risk in the autochthonous population with AS.
Inclusión financiera a nivel mundial: caracterización, comparación internacional y convergencia relativa
Authors: Baronio Alfredo Mario , Buchieri Flavio , Vianco Ana María 
Published: February 2022

Este documento tiene como objetivo caracterizar el nivel de Inclusión Financiera a nivel mundial así como especular con una convergencia relativa de las regiones más rezagadas hacia los más desarrollados en la materia. Consideramos que la situación mundial presenta una amplia dispersión, como lo muestra la metodología desarrollada. A partir del Método de Análisis de Componentes Principales (ACP), aplicado a una muestra de países expuestos por Global Findex, se analiza la formación de clusters, sus características y niveles de dispersión. Estos elementos, a partir de un modelo Logit ordenado, facilitan la construcción de las probabilidades de convergencia de los grupos más rezagados a los más desarrollados en la materia. A partir de estos resultados, los intentos para aumentar los niveles de Inclusión Financiera requerirán de importantes esfuerzos en materia de desarrollo de políticas de tipo público-privado.
Afeto pseudobulbar e ideação suicida: há relação?
Authors: Freitas Filipe Augusto Cursino de , Gomes Neto Antônio Pereira , Winter Remco Frank Peter de Winter , Melo Renata Brant de Souza , Bicalho Albert Louis da Rocha , Christo Paulo Pereira Christo 
Published: February 2022

Objetivo: Afeto pseudobulbar é uma forma de expressão emocional patológica, na qual o paciente com transtorno neurológico apresenta explosões de riso e choro incongruentes ao humor. Está relacionado ao isolamento social. A esclerose múltipla é uma doença relacionada a risco aumentado de suicídio. O objetivo desse estudo é verificar se há alguma relação entre afeto pseudobulbar e ideação suicida em pacientes com esclerose múltipla. Métodos: Foram selecionados 107 pacientes com diagnóstico de esclerose múltipla, estáveis clinicamente, do Ambulatório de Neurologia da Santa Casa de Misericórdia de Belo Horizonte. Eles foram submetidos a coleta de dados padronizada, incluindo coleta de informações clínicas e sociodemográficas. Também foram preenchidas as escalas: Centro de Estudos Neurológicos - Escala de Labilidade, Inventário de Depressão de Beck e Escala de Desesperança de Beck. Resultados: Foram encontrados 41,17% dos pacientes com esclerose múltipla e afeto pseudobulbar, os quais mostraram ideação suicida, enquanto 24,65% dos pacientes com esclerose múltipla e sem afeto pseudobulbar apresentaram tal ideação. Quando o quadro depressivo foi isolado como fator de confusão, não foram encontrados pacientes com afeto pseudobulbar e ideação suicida. Conclusão: Apesar de o afeto pseudobulbar estar relacionado ao isolamento social e aos transtornos de humor, não houve relação entre afeto pseudobulbar e ideação suicida na amostra de pacientes com esclerose múltipla.
Analisis tataniaga tomat di Kecamatan Sumberejo Kabupaten Tanggamus
Authors: Anisah Ramadona Anisah , Sutarni Sutarni , Zaini Muhamad 
Published: February 2022

Kecamatan Sumberejo merupakan salah satu sentra produksi tomat tertinggi di Kabupaten Tanggamus. Kegiatan tataniaga tomat dihadapkan pada persoalan harga yang fluktuatif dan keterbatasan saluran tataniaga di tingkat petani sehingga perlu dilakukan analisis sistem tataniaga tomat jika dilihat dari tingginya jumlah produksi di Kecamatan Sumberejo. Tujuan dari penelitian ini yaitu mengidentifikasi aktivitas tataniaga pada lembaga tataniaga dan saluran tataniaga tomat, menghitung margin tataniaga tomat pada masing-masing saluran tataniaga, menganalisis tingkat efisiensi saluran tataniaga tomat pada masing- masing saluran tataniaga, menganalisis elastisitas transmisi harga dan struktur pasar di Kecamatan Sumberejo Kabupaten Tanggamus. Metode yang digunakan dalam penelitian ini adalah metode kualitatif dan kuantitatif. Data pada penelitian ini adalah dengan mengumpulkan data primer dan data sekunder. Aktivitas tataniaga yang dilakukan oleh petani yaitu diantaranya aktivitas penjualan tomat, penanggungan risiko, dan pembiayaan. Aktivitas tataniaga pada lembaga tataniaga yaitu meliputi aktivitas penjualan tomat, pembelian tomat, pengangkutan, penimbangan, penanggungan risiko, pembiayaan, dan informasi pasar. Saluran tataniaga yang terbentuk di Kecamatan Sumberejo terdapat 3 saluran. Saluran tataniaga I terdiri dari petani-pedagang pengumpul-pedagang pengecer-konsumen. Saluran II terdiri dari petani-pedagang besar-pedagang pengecer. Saluran III terdiri dari petani-pedagang pengumpul-pedagang besar-konsumen. Nilai margin pada saluran tataniaga I,saluran tataniaga II, dan saluran tataniaga III masing-masing diperoleh margin sebesar Rp 3.000, Rp 3.000 dan Rp 4.000. Berdasarkan beberapa indikator dan nilai efisiensi pemasaran maka saluran tataniaga II merupakan saluran yang efisien dibandingkan saluran I dan III. Nilai elastisitas transmisi harga yaitu sebesar 0,785(Et<1). Secara umum struktur pasar tomat mengarah pada pasar persaingan tidak sempurna yaitu pasar oligopsoni.
Performance and Production Cost of Klanting Agroindustry in Gantimulyo Village Pekalongan Subdistrict East Lampung
Authors: Dewi Putu Shabna , Murniati Ktut , Riantini Maya 
Published: February 2022

Tujuan dari penelitian ini adalah untuk menganalisis proses pengadaan bahan baku dengan konsep enam tepat (waktu, tempat, jenis, harga, kualitas, dan kuantitas), kinerja produksi dan biaya produksi agroindustri klanting di Desa Gantimulyo Kecamatan Pekalongan Kabupaten Lampung Timur. Metode penelitian yang digunakan adalah metode studi kasus. Penelitian ini dilaksanakan pada tiga agroindustri klanting di Kecamatan Pekalongan. Lokasi penelitian dipilih secara purposive dengan pertimbangan Desa Gantimulyo merupakan sentra produksi klanting di Kabupaten Lampung Timur. Responden penelitian ini adalah pemilik dan konsumen agroindustri. Pengumpulan data dilakukan pada bulan Januari hingga Februari 2020. Metode analisis yang digunakan adalah metode analisis deskriptif kualitatif dan kuantitatif. Hasil penelitian menunjukkan bahwa dalam pengadaan bahan baku pada agroindustri klanting belum tepat. Kinerja produksi agroindustri klanting di Desa Gantimulyo belum dikatakan baik karena dua dari lima indikator kinerja produksi yaitu indikator kapasitas dan fleksibilitas belum optimal dilakukan oleh ketiga agoindustri klanting. Biaya produksi klanting pada agroindustri klanting berada dibawah harga jual. Artinya, agroindustri klanting di Desa Gantimulyo menguntungkan dan layak diusahakan.

Kata kunci: agroindustri, biaya produksi, kinerja produksi, klanting
PROFESSIONAL LIABILITY INSURANCE AND INCREASED CIVIL PROTECTION OF MEDICAL STAFF
Authors: Tavasoli Sodeh Hamed 
Published: February 2022

Compensation for injuries caused by medical accidents is one of the main branches of insurance under the title of doctors' civil liability insurance. In the present article, we have decided to collect information on the income and expenses of doctors' professional liability insurances to obtain a community view of the coverage of this insurance and to explain the advantages and disadvantages of stakeholders and to propose practical solutions to expand coverage and increase insurance coverage.
In this study, information was collected from the Forensic Medicine Organization of Tehran Province about the amount of complaints and convictions of the medical staff in 1396 by a counting method in a researcher-made checklist and the amount of ransom that various medical professionals were required to pay in 1396 was estimated. Quality was calculated based on percentage and frequency and quantitative information was calculated based on mean and standard deviation.
Out of 4079 complaints, 3343 (52.5%) were acquitted and 1731 (425%) were convicted. The highest number of convictions was related to general surgery, general practitioners and dentists and the lowest convictions were related to traditional medicine, poisoning, nursing and pathology. Complaints from female patients were 2430 cases (59.6%) and the rate of men complaints over time was 3076 cases (75.5%). Between the two groups of medical staff who were required to pay ransom to patients and the group who were not negligent. There was no statistically significant difference in terms of gender. The highest amount of negligence was related to the complaints convicted in the Plastic Surgery Commission in the amount of 924,900,000 Tomans (Iranian currency) and the lowest amount of negligence was related to the complaints condemned in the Traditional Medicine Commission in the amount of 35,700,000 Tomans. Considering the approximate number of 630/269 staff members and considering that if the insurer has spent on average 375/743 Tomans for each limited liability insurance, a significant figure of 250/839/705/200 can be calculated.
As a result, the obligation to insure medical staff requires a determinative. Therefore it is appropriate for the Medical System organization, as the custodian and pioneer of supporting and providing services to the medical staff, to take action in this regard and to achieve this coverage.
TWINSPAN CLASSIFICATION OF VEGETATION FROM NORTH EAST ASPECT OF LOWER TANAWAL ABBOTTABAD, PAKISTAN
Authors: Bibi Adeela 
Published: February 2022

The main objective of this research study was to explore the vegetation of Lower Tanawal, Pakistan from North East aspect. The ordination techniques TWINSPAN, DCA and CCA were used to classify the data. TWINSPAN classified 157 plant species and 20 stands into four plant communities. Four plant communities Dodonaea-Ziziphus-Oxalis, Pinus–Olea–Micromeria, Debregessia-Mentha-Isodon, and Pinus-Punica-Isodon community were noted. This study provides first information about the vegetation of Lower Tanawal, Abbottabad Pakistan from North East aspect.
Evaluación del uso de microorganismos de montaña activados en el cultivo de rosas, Zinacantán, Chiapas, México
Authors: Torres Pérez Juan Cristóbal , Aguilar Jiménez Carlos Ernesto , Vázquez Solís Héctor , Solís López Mariano , Gómez Padilla Eraclio , Aguilar Jiménez José Roberto 
Published: February 2022

La investigación se desarrolló en el municipio de Zinacantán, Chiapas, México, en invernaderos de producción de rosas, localizado a 16° 45′ 35″ latitud norte, 92° 43′ 20″, longitud oeste y a una altitud de 2.162 msnm. El clima de esta región es templado, subhúmedo, con lluvias en verano, con una temperatura media de 21 °C y una precipitación media anual acumulada de 599 mm. El objetivo de este estudio fue evaluar el efecto en el crecimiento de la planta de la utilización de microorganismos de montaña activados (MMA), asperjados bajo dos dosis (10% y 20 %) y dos frecuencias de aplicación (cada 8 y cada 25 días). Los tratamientos se evaluaron bajo el manejo convencional de rosas de la región, y se incluyéron un testigo de manejo convencional y un testigo de manejo ecológico, Los seis tratamientos se expusieron en un diseño completamente al azar, cada uno constituido por una cama de siembra, donde se sembraron dos filas de plantas de rosas bajo un sistema de plantación de tres bolillos; y cada cama presentó un total de 530 plantas. Los resultados indican que los tratamientos de uso del biofertilizante MMA en manejo convencional al 20 % cada 15 días y el tratamiento de MMA al 20% cada 8 días manejado de forma orgánica, fueron estadísticamente mejores para las variables: longitud del tallo, diámetro del tallo, número de hojas, largo de hojas, ancho de hojas, tamaño de la flor y mayor vida de anaquel. Se concluye que la dosis de 20 % de MMA favorece los indicadores de producción de rosas bajo condiciones de invernadero.
ANALISIS DAMPAK WAKTU TANAM TANAMAN TOMAT TERHADAP BIAYA PRODUKSI, HARGA DAN PENDAPATAN USAHATANI DI KECAMATAN ALAS KABUPATEN SUMBAWA
Authors: Safitri Selfiyah , Dipokusumo Bambang , Husni Syarif 
Published: February 2022

ABSTARCT

This study aims to examine the differences in the cost structure and income of tomato farming at various planting seasons in Alas Subdistrict, Sumbawa Regency. The data collected is primary data through questionnaires and secondary data, namely data obtained from BPS and scientific papers related to this research. The analysis technique is a survey technique and is presented in tabular form. The results of this study indicate that the average cost spent on tomato farming in the dry season is IDR 75.047.412/ ha, while the cost of tomato farming during the rainy season is IDR 64.273.351/ ha, the average price of tomatoes in the dry season is IDR Rp. 11,790 per kg, while in the rainy season it is Rp. 5,435 per kg and income. In the dry season, income from tomato farming is Rp 150.430.781/ ha, while for the rainy season it is Rp 20.304.842/ ha. This shows that there are significant differences in the costs and income of tomato farming in various planting seasons in Alas District, Sumbawa Regency.
APLIKASI MODEL PRINCIPAL AGENT PADA IMPLEMENTASI KEBIJAKAN WAJIB TANAM BAWANG PUTIH DI KABUPATEN LOMBOK TIMUR
Authors: Zaini Anas , Anwar Anwar , Zubair Muhammad , Sudjatmiko ‪Dwi Praptomo , Suparmin Suparmin , Sari Ni Made Wirastika 
Published: February 2022

Sebagai salah satu negara importir bawang putih terbesar di dunia, dimana lebih dari 95 persen kebutuhan domestik saat ini dipenuhi dari impor, pemerintah Indonesia berupaya meningkatkan produksi bawang putih dalam negeri. Artikel ini membahas salah satu upaya peningkatan produksi bawang putih tersebut yaitu kebijakan wajib tanam bawang putih oleh importir yang bermitra dengan petani. Hubungan kemitraan tersebut kemudian dianalisis menggunakan Model Principal Agent, dimana hubungan kerja masing-masing komponen pendukung kebijakan didiskusikans dan dievaluasi secara kritis. Hak dan kewajiban para pihak (principal dan agent) dianalisis dan dievaluasi implementasinya berdasarkan kontrak Perjanjian Kerja Sama (PKS) yang telah ditandatangani, serta peran dan fungsi koordinasi pemerintah melalui dinas terkait dievaluasi berdasarkan petunjuk teknis pelaksanaan kebijakan. Hasil penelitian menunjukkan bahwa implementasi kebijakan wajib tanam oleh importir yang bermitra dengan petani bawang putih telah sesuai dengan PKS dan menguntungkan para pihak tanpa adanya moral hazard. Namun demikian peran koordinatif pemerintah sangat minimal terutama pada tahap monitoring dan pelaporan hasil.
PENGARUH POPULASI TANAMAN DAN DOSIS BIOFERTILIZER EXTRAGEN TERHADAP PERTUMBUHAN DAN HASIL TANAMAN WORTEL (Daucus carota L.) DI DATARAN RENDAH
Authors: Putri Riema Rimanda , Nikmatullah Aluh , Suheri Herman 
Published: February 2022

A research with an aim to determine the effect of plant population, rate of biofertilizer ExtraGEN and their interaction on the growth and yield of carrot (Daucus carota L.) plants on the lowland was conducted. The experiment was carried out in the University of Mataram experimental field located in Narmada, West Lombok, NTB at an altitude of 136 m above the sea level from May to July 2019. The research used a Completely Randomized Factorial Design, consisting of 2 factors, namely the plant population and rate of biofertilizer ExtraGEN. The plant population consisted of 3 level : 1 plant/polybag, 3 plants/ polybag and 5 plants/polybag. The rate of biofertilizer ExtraGEN consisted of 4 levels: without biofertilizer ExtraGEN (control), with 100 ml/polybag biofertilizer ExtraGEN, with 200 ml/polybag biofertilizer ExtraGEN, and with 400 ml/polybag biofertilizer ExtraGEN. The combinations resulted in 12 interactions which were repeated 5 times. The data obtained were analyzed using Analysis of Variance (ANOVA) at 5 % significant level and followed by an Honestly Significant Difference (HSD) at the same level. The results showed that plant population affected the rate of increase in the length of petioles, total fresh weight of the roots/polybag and total dry weight of roots/polybag, but did not affect other parameters. Higher the plant population, lowered the rate of increase in length of the petioles increased the total weight of fresh roots biomass/polybag and the weight of total dry biomass/ploybag. Biomass weight per plant was obtained 4,07 g population of 1 plant/polybag, 1,37 g population of 3 plants/polybag and 0,56 g population of 5 plants/polybag. The rates of biofertilizer ExtraGEN did not affect the growth and yield of carrot plants on the lowland.
KARAKTERISASI POPULASI C8 HASIL SELEKSI MASSA JAGUNG KETAN (Zea mays L. var ceratina) LOKAL BIMA
Authors: Andriastuti Alviana Itriyani , Yakop Uyek Malik , Ujianto Lestari 
Published: February 2022

Penelitian ini bertujuan untuk mengetahui keunggulan karakter kuantitatif dari populasi C8 hasil seleksi massa Jagung lokal ketan Bima terhadap C0 dan varietas unggul Anoman. Penelitian ini dilakukan pada bulan Desember 2019 sampai Maret 2020 di Desa Mambalan, Sayang-Sayang, Kabupaten Lombok Barat, Nusa Tenggara Barat. Rancangan yang digunakan adalah Rancangan Acak Kelompok (RAK) dengan 3 perlakuan dan diulang sebanyak 8 kali sehingga didapatkan 24 unit percobaan. Data dianalisis dengan analis is keragaman pada taraf nyata 5%. Jika terdapat perlakuan yang berbeda nyata maka dilanjutkan dengan uji lanjut Duncan Multiple Range (DMRT) 5%. Perlakuan yang digunakan merupakan genotipe populasi siklus kedelapan hasil seleksi massa (C8), populasi awal (C0), dan populasi varietas unggul bersari bebas Anoman. Hasil penelit ian menunjukkan bahwa karakter kuantitatif pada populasi C8 lebih baik secara umum dibandingkan dengan populasi tetuanya C0 yang ditunjukkan oleh sifat tinggi tanaman, diameter batang, bobot tongkol kering per tanaman, bobot biji kering pipil per tanaman, dan bobot 100 biji yang meningkat secara nyata. Pada populasi C8, karakter kuantitatif bobot biji kering pipil per tanaman sebesar 76,74 g/tanaman atau setara dengan 4,39 ton/ha mengala mi peningkatan daya hasil yang tinggi, tidak berbeda nyata dengan varietas unggul Anoman.
Komunitas Makrofauna Tanah pada Lahan Bekas TPA Gunung Tugel Kabupaten Banyumas
Authors: Susanto Susanto , Rahayu Astriana Putri 
Published: February 2022

Penelitian ini bertujuan untuk mengetahui dan mengungkap komunitas makrofauna tanah yang meliputi cacah individu, keanekaragaman dan dominansi serta kualitas lingkungan tanah di lahan eks TPA Gunung Tugel Desa Kedung Randu Kecamatan Patikraja Kabupaten Banyumas. Metode yang digunakan adalah purposive random sampling. Pengambilan sampel dilakukan selama enam bulan yaitu bulan Januari-Juni 2021 sebanyak enam kali dengan interval waktu selama satu bulan yaitu waktu siang hari (pukul 06.00 – 08.00) dan malam hari (pukul 18.00-20.00). Pengambilan sampel tanah dan pengukuran kualitas tanah dilakukan di dua lokasi penelitian, yaitu lokasi I di area sebelah utara dan timur lahan eks TPA Gunung Tugel dan lokasi II di area sebelah barat dan selatan lahan eks TPA Gunung Tugel. Hasil sampling diidentifikasi menggunakan mikroskop dan mengacu pada buku An Introduction to the Study of Insect dan buku Ekologi Hewan Tanah. Hasil penelitian menunjukkan cacah individu makrofauna tanah diperoleh sebanyak 1612 ekor yang termasuk kedalam 16 spesies, 13 Famili, dan 8 Ordo. Indeks keanekaragaman makrofauna tanah tergolong sedang yaitu kisaran 1,006 – 1,098 dengan rata-rata sebesar 1,066. Indeks dominansi makrofauna tanah pada lahan eks TPA Gunung Tugel tergolong kedalam kategori rendah dengan nilai kisaran antara 0,334 – 0,489 dengan rata-rata 0,374.