bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estimation of Stature from Arm Span: A Prospective Study Among Medical Students of Rangpur Medical College
Authors: Sultana Riada , Anwar Selina , Islam Shamima , Maknunnahar - 
Published: November 2022

Background: Arm span is one of the most reliable body parameters for predicting the stature of an individual. It is useful in an age-related loss in stature and in identifying individuals with disproportionate growth abnormalities and skeletal dysplasia.
Objectives: The present study was undertaken to determine whether there is any correlation between stature and arm span and estimate stature from arm span by using multiplication factor and assess the effectiveness of the above estimation by comparing the ‘estimated’ values with the measured values.
Methods: This is a cross-sectional analytical study done in the Department of Anatomy, Rangpur Medical College, Rangpur, from January to December 2018 on purposively selected 700 medical students (350 male and 350 female). Arm span along with their stature was measured directly from the subjects by using an anthropometric technique by a measuring tape. Multiplication factors were estimated for estimating stature and comparison were made between measured and estimated stature using paired “t” test.
Results: The mean normal value of arm span was 170.48±7.38 cm in males and 156.13±5.98 cm in females and the stature was 168.93±0.06 cm in males and 156.23±0.05 cm in females. The multiplication factor was estimated for the same hand measurements with the stature. A significant positive correlation was found in the case of arm span with stature.
Conclusion: Arm span is a valid measure of stature for both adult males and females.
J Rang Med Col. September 2022; Vol. 7, No. 2:47-51
Reconciliation of Ulama and Umara in Socio-Political Conflict through Sufistic Approach
Authors: Ridho Hilmi , Mirwan Mirwan 
Published: November 2022

Ulama have a role as cultural and moral figures to protect and foster people in social life. Umara is a political elite tasked with carrying out state political policies and maintaining state ideology. In the socio-political context, the ulama and umara synergize with each other to realize the unity and harmony of the people in religion and the state. In reality, some Islamic organizations led by ulamas create a commotion in the country and are very opposed to the umara policy, causing divisions among community groups. Based on the problems above, the study's results show that (1) the involvement of ulama and umara in the political stage is not new. That strong support from the Shari'a is exemplified by the Prophet Muhammad and Khulafa Ar-Rashidin. (2) Ulama and umara should create an ideal society, namely a society that is independent and runs on the correct principles. (3) Social Sufism offers a solution to overcome conflicts between ulama and umara amid society.
Online-Offline in Religion; Observing Islamic Learning Patterns in Online Media
Authors: Zuhri Achmad Muhibbin , Alfin Jauharoti 
Published: November 2022

This study aims to unravel the phenomenon of digital society in understanding and learning Islam through the internet. The current human tendency to rely on information available through smartphones has given birth to the reality of shifting learning patterns that do not have to meet directly with the teacher. Even the presence of a virtual teacher is considered sufficient to justify an excellent religious way. This study uses a qualitative method with a netnographic approach that intends to reveal social phenomena in cyberspace. This method uses a particular analytical technique offered, AMS (Siber Media Analysis), which goes through 4 levels: Media room level, media document level, media object level, and experience level. This study found that online internet users can access information about religious rituals and procedures for doing them. So, internet users are part of the world's religious adherents who carry out the same religious creed. On the other hand, religious authority as a source of knowledge in learning Islam on the internet is not always institutional but can also be individual. As a result, the Islamic pattern of understanding Islam among netizens is more accessible, inclusive, egalitarian, and shows multidimensional interactions between individuals and other religious groups.
ANALISIS PENGARUH PELATIHAN DAN KEMAMPUAN KERJA GUNA MENINGKATKAN KINERJA KARYAWAN PT. DEWI SRI KECAMATAN WLINGI KAB. BLITAR
Authors: Damayanti Kristya , Sasmito Aldi 
Published: November 2022

Penelitian yang dilakukan di Perkebunan Kopi PT. Dewi Sri bertujuan untuk mengetahui pengaruh pelatihan dan kemampuan kerja terhadap kinerja karyawan. Penelitian ini mengambil responden sebanyak 67 orang. Metode pengumpulan data dilakukan melalui kuesioner / angket, dokumentasi dan wawancara. Teknik analisis data pada penelitian ini adalah analisis deskriptif kuantitatif menggunakan uji validitas, uji reliabilitas, uji asumsi klasik (normalitas, heteroskedastisitas, autokolerasi, multikolinearitas), analisis regresi linier bergada, pengujian hipotesis (uji parsial, uji simultan) dengan bantuan software SPSS. Penelitian ini menggunakan variabel pelatihan dan kemampuan kerja untuk variabel bebas (independen) dan kinerja karyawan untuk variabel terikatnya (dependen). Hasil uji parsial (nilai uji t) menunjukan bahwa variabel independen pelatihan kerja X1 dan kemampuan kerja X2 masing - masing berpengaruh terhadap variabel dependen yaitu kinerja karyawan (Y). Hasil uji simultan (uji F) menunjukan bahwa variabel independen pelatihan kerja X1 dan kemampuan kerja X2 bersama - sama berpengaruh terhadap variabel dependen yaitu kinerja karyawan (Y).
ANALISIS KINERJA GENERATOR INDUKSI 3 FASA BERDASARKAN REGULASI TEGANGANNYA
Authors: Rachmat Sutjipto  , Heri Sungkowo  , Epiwardi Epiwardi  
Published: November 2022

Generator induksi 3 fasa bisa digunakan sebagai generator cadangan dari operasi generator sinkron 3 fasa. Generator induksi 3 fasa dapat dibuat dari motor induksi slip ring 3 fasa atau motor sangkar 3 fasa untuk generator induksi SEIG (Self Excited Induction Generator). Motor induksi slip ring 3 fasa berfungsi sebagai generator induksi setelah belitan rotornya disuplai sumber DC dan diputar menggunakan prime mover, sedangkan pada generator SEIG, tegangan listrik dihasilkan dengan bantuan 3 kapasitor yang terhubung delta. Permasalahan yang muncul dalam pengoperasian adalah timbulnya rugi tegangan saat dilaksanakan variasi pembebanan. Untuk menjawab permasalahan tersebut maka diadakan 3 jenis pengetesan (DC Test, Open Circuit Test dan Load Test) pada kedua generator tesebut. Setelah semua percobaan dilaksanakan dan dianalisa maka diketahui bahwa besarnya tegangan output dari generator induksi 3 fasa dipengaruhi oleh besarnya kecepatan generator dan besarnya arus eksitasi. Proses eksitasi dari kedua generator tersebut berbeda, eksitasi dari generator SEIG ditentukan besar dan jenis hubungan kapasitor eksitasi sedangkan generator induksi lainnya ditentukan oleh besarnya tegangan DC yang disuplaikan ke belitan rotor. Tegangan output dari kedua generator induksi juga dipengaruhi oleh besar dan jenis bebannya. Diketahui pula bahwa generator induksi SEIG mempunyai rugi tegangan dan % regulasi tegangan yang lebih besar dikarenakan harga parameter belitannya lebih besar. Untuk menstabilkan tegangan output generator maka dapat dilaksanakan dengan mengatur besarnya arus eksitasi dan kecepatan dari kedua generator induksi tersebut, dengan tetap memperhatikan kemampuan belitan eksitasi dan frekuensi yang dibutuhkan oleh beban serta kesediaan kapasitor untuk generator SEIG.
Integrated analysis of transcriptomics, proteomics and metabolomics data reveals the role of SLC39A1 in renal cell carcinoma
Authors: Yuan Yulin , Liu Zimeng , Li Bohan , Gong Zheng , Piao Chiyuan , Du Yang , Zhan Bo , Zhang Zhe , Dong Xiao 
Published: November 2022

Purpose: Accumulating evidence suggests that solute carrier family 39 member 1 (SLC39A1) conceivably function as a tumor suppressor, but the underlying mechanism in renal cell carcinoma (RCC) is poorly understood.Methods: OSRC-2 renal cancer cells were first transfected with SLC39A1 overexpressed vectors and empty vectors and then used in transcriptomics, proteomics, and metabolomics integrated analyses.Results: SLC39A1 significantly altered several metabolisms at transcriptional, protein and metabolic levels, including purine and pyrimidine metabolism, amino acids and derivatives metabolism, lactose metabolism, and free fatty acid metabolism. Additionally, SLC39A1 could promote ferroptosis, and triggered significant crosstalk in PI3K-AKT signal pathway, cAMP signal pathway, and peroxisome proliferators-activated receptor (PPAR) signal pathway.Conclusion: We found SLC39A1 transfection impaired tumor metabolism and perturbed tumor metabolism-related pathways, which was a likely cause of the alteration in cell proliferation, migration, and cell cycle progression in RCC cells. These multi-omics analyses results provided both a macroscopic picture of molecular perturbation by SLC39A1 and novel insights into RCC tumorigenesis and development.
Efficacy and safety of drug-coated balloon combined with cutting balloon for side branch of true coronary bifurcation lesions: Study protocol for a multicenter, prospective, randomized controlled trial
Authors: Wu Haoyu , Deng Jizhao , Liang Lei , Lei Xinjun , Yao Xiaowei , Han Wenqi , Chen Haichao , Shou Xiling 
Published: November 2022

BackgroundCoronary bifurcation lesions are common of percutaneous coronary intervention (PCI), and the optimal interventional therapy strategy is still a matter of debate and remains a challenge for interventional cardiologists. The provisional stenting technique is still a preferred method for most bifurcation lesions, but restenosis of the side branch (SB) occurs in approximately 17–19% of cases. Therefore, the dilemma of reducing SB restenosis still exists, and further research on strategies to reduce restenosis for SB is necessary. Drug-coated balloon (DCB) can reduce clinical events in small vessel disease and in-stent restenosis. The efficacy and safety of DCB for SB of true coronary bifurcation lesions have not been fully investigated. A randomized comparison of DCB combined with cutting balloon angioplasty vs. cutting balloon angioplasty for SB has never been published.Methods and designThe purpose of this study is to explore the superiority of DCB combined with cutting balloon vs. cutting balloon angioplasty for SB after main vessel (MV) drug-eluting stent implantation of true coronary bifurcation lesions. This study is a multicenter, prospective, randomized controlled trial including 140 patients with true coronary bifurcation lesions. Patients will be randomized in a 1:1 manner to receive either DCB combined with cutting balloon or cutting balloon angioplasty for SB after MV drug-eluting stent implantation. The primary endpoint is the evaluation of late lumen loss (LLL) of SB at the 9-month follow-up. The secondary endpoints include procedural success during initial hospitalization, LLL of MV at the 9-month follow-up, binary angiographic restenosis in MV and SB at the 9-month follow-up, the proportion of patients with a final post-PCI quantitative flow ratio result ≤ 0.80 for SB at the 9-month follow-up, and major adverse cardiac events during the 24-month follow-up.ConclusionsThis clinical trial will provide evidence as to whether DCB combined with cutting balloon for SB of true coronary bifurcation lesions is a superior treatment approach.Trial Registration NumberChiCTR2000040475.DisseminationThe results of this clinical trial will be published in a peer-reviewed journal.
High expression of TTC21A predicts unfavorable prognosis and immune infiltrates in clear cell renal cell carcinoma
Authors: Lin Junhao , Nong DeYong , Wang Wei , Guo Xiaobin , Li ChunLin , Li BingCai , Wang Haojian , Chen Zhi , Li XiMing , Huang GuiHai , Li Wei 
Published: November 2022

Background: Clear cell renal cell carcinoma (ccRCC) is the most common pathological type of renal cell carcinoma. Tetratricopeptide repeat domain 21A (TTC21A), known as a component of intraflagellar transport complex A which is essential for the function of cilia, However, the role of TTC21A remains unclear in ccRCC. For the first time, we explore the role and potential mechanism of TTC21A in ccRCC based on multiple databases.Methods: TTC21A expression across all TCGA tumor was analyzed via Tumor Immune Estimation Resource (TIMER) site. The correlation between TTC21A and clinicopathologic characteristics of ccRCC was analyzed with TCGA database. The diagnostic and prognostic value of TTC21A was evaluated by receiver operation characteristic curve, Kaplan-Meier plotter and Cox regression respectively. Moreover, functional enrichment analysis of TTC21A and the co-expression genes were performed by Gene Set Enrichment Analysis. The correlation of TTC21A and immune infiltration were evaluated by single sample Gene Set Enrichment Analysis.Results: Pan-cancer analysis indicated that TTC21A was highly expressed in ccRCC and other cancer. In addition, elevated expression of TTC21A was associated with worse overall survival in ccRCC patients. Functional enrichment analysis showed that TTC21A and the co-expressed genes enriched in glucose metabolism and energy metabolism. Moreover, TTC21A expression was associated with infiltrating levels of dendritic cell, nature killer cell and other immune marker sets.Conclusion: The results of analysis indicate that expression of TTC21A is associated with poor prognosis and immune infiltrating in ccRCC, which suggested TTC21A might be used as a potential predictor and target of treatment in ccRCC.
Lyme borreliosis in pregnancy and associations with parent and offspring health outcomes: An international cross-sectional survey
Authors: Leavey Katherine , MacKenzie Rachel K. , Faber Sue , Lloyd Vett K. , Mao Charlotte , Wills Melanie K. B. , Boucoiran Isabelle , Cates Elizabeth C. , Omar Abeer , Marquez Olivia , Darling Elizabeth K. 
Published: November 2022

BackgroundLyme disease (LD) is a complex tick-borne pathology caused by Borrelia burgdorferi sensu lato bacteria. Currently, there are limited data regarding the health outcomes of people infected during pregnancy, the potential for perinatal transmission to their fetus, and the long-term effects on these children. Therefore, the primary objective of this survey study was to investigate the impact of LD in pregnancy on both the parent and their offspring.MethodsA seven-section survey was developed and administered in REDCap. Although recruitment was primarily through LD-focused organizations, participation was open to anyone over the age of 18 who had been pregnant. Participant health/symptoms were compared across those with “Diagnosed LD,” “Suspected LD,” or “No LD” at any time in their lives. The timing of LD events in the participants’ histories (tick bite, diagnosis, treatment start, etc.) were then utilized to classify the participants’ pregnancies into one of five groups: “Probable Treated LD,” “Probable Untreated LD,” “Possible Untreated LD,” “No Evidence of LD,” and “Unclear.”ResultsA total of 691 eligible people participated in the survey, of whom 65% had Diagnosed LD, 6% had Suspected LD, and 29% had No LD ever. Both the Diagnosed LD and Suspected LD groups indicated a high symptom burden (p &lt; 0.01). Unfortunately, direct testing of fetal/newborn tissues for Borrelia burgdorferi only occurred following 3% of pregnancies at risk of transmission; positive/equivocal results were obtained in 14% of these cases. Pregnancies with No Evidence of LD experienced the fewest complications (p &lt; 0.01) and were most likely to result in a live birth (p = 0.01) and limited short- and long-term offspring pathologies (p &lt; 0.01). Within the LD-affected pregnancy groups, obtaining treatment did not decrease complications for the parent themselves but did ameliorate neonatal health status, with reduced rates of rashes, hypotonia, and respiratory distress (all p &lt; 0.01). The impact of parent LD treatment on longer-term child outcomes was less clear.ConclusionOverall, this pioneering survey represents significant progress toward understanding the effects of LD on pregnancy and child health. A large prospective study of pregnant people with LD, combining consistent diagnostic testing, exhaustive assessment of fetal/newborn samples, and long-term offspring follow-up, is warranted.
Lipoprotein(a) and residual vascular risk in statin-treated patients with first acute ischemic stroke: A prospective cohort study
Authors: Wang Lanjing , Liu Lijun , Zhao Yanhong , Chu Min , Teng Jijun 
Published: November 2022

ObjectivesStatins either barely affect or increase lipoprotein(a) [Lp(a)] levels. This study aimed to explore the factors correlated to the change of Lp(a) levels as well as the relationship between Lp(a) and the recurrent vascular events in statin-treated patients with first acute ischemic stroke (AIS).MethodsPatients who were admitted to the hospital with first AIS from October 2018 to September 2020 were eligible for inclusion. Correlation between the change of Lp(a) levels and potential influencing factors was assessed by linear regression analysis. Cox proportional regression models were used to estimate the association between Lp(a) and recurrent vascular events including AIS, transient ischemic attack, myocardial infarction and coronary revascularization.ResultsIn total, 303 patients, 69.6% males with mean age 64.26 ± 11.38 years, completed the follow-up. During the follow-up period, Lp(a) levels increased in 50.5% of statin-treated patients and the mean percent change of Lp(a) levels were 14.48% (95% CI 6.35–22.61%). Creatinine (β = 0.152, 95% CI 0.125–0.791, P = 0.007) and aspartate aminotransferase (AST) (β = 0.160, 95% CI 0.175–0.949, P = 0.005) were positively associated with the percent change of Lp(a) levels. During a median follow-up of 26 months, 66 (21.8%) patients had a recurrent vascular event. The median time period between AIS onset and vascular events recurrence was 9.5 months (IQR 2.0–16.3 months). The on-statin Lp(a) level ≥70 mg/dL (HR 2.539, 95% CI 1.076–5.990, P = 0.033) and the change of Lp(a) levels (HR 1.003, 95% CI 1.000–1.005, P = 0.033) were associated with the recurrent vascular events in statin-treated patients with first AIS. Furthermore, the on-statin Lp(a) levels ≥70 mg/dL (HR 3.612, 95% CI 1.018–12.815, P = 0.047) increased the risk of recurrent vascular events in patients with low-density lipoprotein cholesterol (LDL-C) levels &lt; 1.8 mmol/L.ConclusionsLp(a) levels increased in half of statin-treated patients with first AIS. Creatinine and AST were positively associated with the percent change of Lp(a) levels. Lp(a) is a determinant of residual vascular risk and the change of Lp(a) is positively associated with the risk of recurrent vascular events in these patients.
Dorsal root ganglion pulsed radiofrequency using bipolar technology in patients with lumbosacral radicular pain duration ≥ 2 years
Authors: Luo Qipeng , Zhao Zifang , Yi Duan , Li Shuiqing , Liu Xiaoguang 
Published: November 2022

BackgroundTransforaminal epidural steroid injection (TFESI) or dorsal root ganglion pulsed radiofrequency (PRF) are alternative treatments for lumbosacral radicular pain (LSRP). This study aimed to investigate the clinical efficacy of TFESI combined with dorsal root ganglion PRF using bipolar technology to treat LSRP in patients with pain duration ≥ 2 years.MethodsThis prospective single-armed cohort study included 20 patients with LSRP duration ≥ 2 years, who underwent treatment of TFESI combined with bipolar PRF. The primary outcomes included numerical rating scale (NRS) and successful treatment rate (pain relief ≥50%). The secondary outcomes included Oswestry Disability Index (ODI), patient satisfaction using the modified MacNab criteria, severe complications, hospital stay and total costs. The final follow-up was 6 months postoperatively.ResultsThe successful treatment rate and average pain relief at 6 months postoperatively were 80% and 73.0% ± 17.5%, respectively. The successful treatment rates in patients with and without prior intervention history at 6 months postoperatively were 77.8% and 81.8%, respectively. The mean NRS score significantly decreased from 6.5 ± 0.8 to 1.1 ± 0.7 at 2 weeks postoperatively, to 1.3 ± 0.7 at 3 months postoperatively, and to 1.7 ± 1.0 at 6 months postoperatively (all P &lt; 0.001), while the mean ODI score significantly decreased from 43.5 ± 2.5 to 22.5 ± 4.3 at 2 weeks postoperatively, to 20.0 ± 3.5 at 3 months postoperatively, and to 19.5 ± 3.6 at 6 months postoperatively (all P &lt; 0.001). The excellent and good patient satisfaction at 6 months postoperatively was 85%. No severe complications were observed in this cohort. The average hospital stay and total costs were 3.0 ± 0.5 days and 3.36 ± 0.77 thousand dollars, respectively.ConclusionThe treatment of TFESI combined with PRF using bipolar technology might be an alternative option to treat chronic LSRP in patients with pain duration ≥ 2 years after a failure of conservative treatments, with a favorable 6-month efficacy and inexpensive total costs. However, long-term outcomes and superiority of bipolar procedure over monopolar procedure in patients with longer pain duration should be further investigated in future studies.
Prefrontal cortex neural activity predicts reduction of non-suicidal self-injury in adolescents with major depressive disorder: An event related potential study
Authors: Liu Huishan , Wen Yujiao , Liang Xiumei , Xu Yifan , Qiao Dan , Yang Chunxia , Han Min , Li Hong , Ren Tian , Zhang Xuemin , Li Gaizhi , Liu Zhifen 
Published: November 2022

BackgroundNon-suicidal self-injury (NSSI) is common in adolescent MDD, which is also a risk factor for suicide. However, there is few research on biomarkers and predictors about treatment response of NSSI. The purpose of this study was to find the difference of P300 between adolescent MDD with NSSI and healthy controls, and to explore whether the baseline electrophysiological level can predict the change of NSSI after treatment.MethodsWe collected 62 first-episode drug-naïve MDD adolescents with NSSI (MDD with NSSI group) and 44 healthy controls (HC group). The demographic data, HAMD score, self-injury frequency and electrophysiological level of NSSI group and HC group were collected. The HAMD score, frequency of NSSI in was also collected after 8 weeks of antidepressant treatment.ResultsCompared to HC, the latency of the N2, P3a, and P3b components were significantly prolonged, whereas the amplitude of P3a and P3b were decreased in the MDD with NSSI group (P &lt; 0.001). The frequency of self-injury decreased significantly after treatment (P &lt; 0.001). Regression analysis showed that the amplitudes of P3b had a significant positive predictive effect on the rate of change of NSSI frequency after 8 weeks.ConclusionP3b at baseline can be used as potential predictor for the reduction of NSSI in adolescent MDD.