bluuebunny/crossref_metadata_2025_split huggingface dataset:
Primary Hyperaldosteronism as a Cause of Refractory Arterial Hypertension. A Clinical Case
Authors: Казакова М.И. , Галицкая С.С. 
Published: February 2022

В последние годы достигнут значительный прогресс в понимании патогенеза первичного гиперальдостеронизма (ПГА), расширены показания для проведения скрининга, разработаны алгоритмы для медикаментозного и хирургического лечения. У пациентов с ПГА более высокий риск развития инфаркта миокарда, кардиального фиброза, диастолической дисфункции, гипертрофии миокарда левого желудочка, дилатации полостей сердца и возникновения аритмий по сравнению с пациентами с эссенциальной артериальной гипертензией. Риск внезапной сердечной смертности у этих пациентов увеличивается в 10-12 раз. Своевременно поставленный диагноз ПГА позволяет предотвратить развитие осложнений, улучшить качество жизни и снизить инвалидизацию пациентов. В статье представлен клинический случай диагностики и лечения первичного гиперальдостеронизма как наиболее частой причины вторичной артериальной гипертензии. Стертая клиническая картина в дебюте заболевания и отсутствие гипокалиемии маскируют первичный гиперальдостеронизм под эссенциальную гипертензию и приводят к позднему выявлению заболевания.
In recent years, significant progress has been made in understanding the pathogenesis of primary hyperaldosteronism (PHA). The indications for screening have been expanded; the algorithms for drug and surgical treatment have been developed. Patients with PHA have a higher risk of development of myocardial infarction, cardiac fibrosis, diastolic dysfunction, left ventricular hypertrophy, dilation of the heart cavities, and occurrence of arrhythmias if compared with patients with essential arterial hypertension. The risk of sudden cardiac death in these patients increases by 10-12 times. A timely diagnosis of PHA can prevent the development of complications, improve the quality of life, and reduce the disability of patients. The article presents a clinical case of diagnosis and treatment of primary hyperaldosteronism as the most common cause of secondary arterial hypertension. A blurred clinical picture at the onset of the disease and the absence of hypokalemia mask primary hyperaldosteronism as essential hypertension and lead to late detection of disease.
Tooth Color Formation Under the Influence of the Microcirculatory Bed of Pulp
Authors: Новак Н.В. 
Published: February 2022

Приведены результаты изучения влияния красного цвета пульпы на формирование оттенков зуба пациентов разных возрастных групп. Показано, что на процесс отражения света от пульпы и формирование цвета зуба влияют несколько факторов: степень минерализации эмали и дентина; выраженность деградации пульпы и размеры полости зуба; толщина твердых тканей. Оттенки цвета зуба определяются совокупностью его оптических характеристик, включающих отражение, пропускание, рассеивание света и флуоресцентные свойства. Свет, отраженный от пульпы, влияет на формирование оттенков цвета зуба, о чем свидетельствует смещение значений коэффициентов диффузного отражения зубов при имитации пульпы в длинноволновую область спектра, соответствующую красно-коричневым оттенкам. Такие изменения наиболее характерны для зубов пациентов среднего (26–44 лет) и старшего (45–60 лет) возраста. Для этих возрастных групп коэффициенты диффузного отражения имеют обратную линейную корреляционную связь с размерами полости и вестибулярной стенки зуба. Результаты проведенного исследования по изучению влияния пульпы на параметры отражения света от поверхности зубов пациентов разного возраста имеют не только научную новизну, но и практическую значимость. На их основе разработан способ изготовления цветокорригирующего винира с воссозданием цвета пульпы.
Results of studying of influence of red color of a pulp on formation of shades of tooth of patients of different age groups are given in article. It is shown that process of reflection of light from a pulp and formation of color of tooth is influenced by several factors: degree of a mineralization of enamel and dentine; expressiveness of degradation of a pulp and sizes of a cavity of tooth; thickness of solid fabrics. Shades of color of tooth are defined by set of his optical characteristics including reflection, transmission, dispersion of light and fluorescent properties. Light reflected from a pulp influences formation of shades of color of tooth what the shift of values of coefficients of diffusion reflection of teeth at imitation of a pulp to the long-wave area of a range corresponding to red-brown shades testifies to. Such changes are most characteristic of teeth of patients of an average (26–44 years) and the senior (45–60 years) of age. For these age groups coefficients of diffusion reflection have the return linear correlation communication with the sizes of a cavity and a vestibular wall of tooth. Results of the conducted research on studying of influence of a pulp on parameters of reflection of light from the surface of teeth of patients of different age have not only scientific novelty, but also the practical importance. On their basis the way of production of a correcting color veneer with reconstruction of color of a pulp is developed.
Determinando el pronóstico del paciente Gran Quemado: Correlación del Índice de Garcés con el Abbreviated Burn Severity Index (ABSI)
Authors: Macchiavello Macho Roberto Ariel , Paulos Parot María Angélica , Soto Diez Carolina , Calcagno Lüer Manuel , Barril Merino Carlos 
Published: February 2022

Introducción: Existen distintos scores pronósticos para determinar probabilidad de muerte en pacientes quemados. El Índice de Garcés (IG) utilizado en Chile, no es aceptado mundialmente. Decidimos evaluar la correlación entre IG y Abbreviated Burn Severity Index (ABSI), de uso generalizado. Métodos: Estudio descriptivo analítico transversal de pacientes quemados subidos a la plataforma online “Registro Nacional de Quemados” y luego ingresados a nuestro centro entre Julio 2017 y Julio 2018. Se calculó coeficiente de correlación de Pearson entre IG y ABSI. Se normalizan ambas variables para hacerlas comparables y se calculó concordancia entre estas con coeficiente de correlación de Lin. Con análisis de regresión logística se calculó probabilidad de fallecer asociada para ambas variables y se compararon áreas de las curvas ROC de ambos scores. Resultados: De 141 pacientes, 15 fallecieron durante hospitalización, con medias de IG de 104 ± 49 puntos y ABSI 7 ± 2. El coeficiente de correlación de Pearson entre IG y ABSI demostró ser muy alto con un valor de 0,928. El coeficiente de correlación de Lin entregó concordancia moderada con un valor de 0,93. Al comprobar cuál de las dos puntuaciones predice mejor la probabilidad de muerte mediante análisis de sensibilidad y especificidad, la curva ROC cubre más área en IG (0,82 vs 0,83), sin ser estadísticamente significativo. Conclusiones: Ambos índices, IG y ABSI, son muy similares para predecir la probabilidad de muerte, por lo cual son equiparables a la hora de compartir resultados de estudios científicos.
Tratamiento quirúrgico de las Ulceras por radionecrosis con colgajos musculocutáneos y fasciocutáneos .
Authors: Calderón Wilfredo Luis , Mora Godoy Roberto , Obaid García Miguel , Camacho Martino Juan Pablo , Guler Gonzalez Kenneth , Lombardi Azócar Juan José , Subiabre Rodrigo 
Published: February 2022

Objetivo: Presentar el tratamiento quirúrgico de las Ulceras por radionecrosis mediante colgajos Miocutáneos y Fasciocutáneos pediculados y microquirúrgicos.Introducción: La Ulcera con radionecrosis debe ser resecada ampliamente y reparada con colgajos miocutáneos y fasciocutáneosMaterial y Método: La casuística es de 31 pacientes portadores de ulceras por radionecrosis resueltas con colgajos miocutáneos y fasciocutáneos. Ellos han sido pediculados y microquirúrgicos. Las edades fluctuaron entre 30 y 75 años operados entre el 2000 y el 2019.Resultados: Se realizaron 19 colgajos musculares o miocutáneos y 12 fasciocutáneos en diferentes zonas del organismo. Los colgajos correspondieron a : temporal, latissimus dorsi de pediculo central y en reversa , latissimus dorsi microquirúrgicos, recto abdominal, escapular microquirúrgico, para escapular, gracilis ,gastrocnemius, rectus femoris, cubital microquirúrgico, fasciocutaneos: cone flap y de rotación local. Las complicaciones fueron dehiscencia de herida operatoria suturada y celulitis tratada con antibióticos. No hubo necrosis completa de los colgajos. El seguimiento fue de 3 a 6 meses.Discusión: En ésta serie hemos utilizados los colgajos músculo cutáneos de preferencia, los fascio cutáneos los hemos reservados para aquellos casos en los que por razones anatómicas, de localización de las úlceras, era más adecuado usar estos últimos, como en las lesiones planas o poco profundas.Generalmente los colgajos fueron pediculados y en determinados casos, cuando el tejido vecino de reparación no estaba disponible, realizamos colgajos con microcirugía.Conclusión: El tratamiento de las úlceras por radionecrosis es efectivo cuando se realiza desbridamiento exhaustivo con cobertura inmediata con colgajos musculares o músculocutáneos y fasciocutáneos. Fueron colgajos pediculados y microquirúrgicos.
Arabic Teacher Creativity Towards The Use Of Information Technology In Distance Learning
Authors: Sabella Nabella , Hasan Hasan 
Published: February 2022

<p class="acmabstract"><em><span>The main problem in this study, along with the COVID-19 pandemic, which has plagued Indonesia for more than a year, has caused various problems and impacted various aspects of life, especially in education. To reduce the spread of COVID-19, the government enforces distance learning, which also impacts learning Arabic and requires teachers to develop creativity in learning. Using a qualitative field research method, this study aims to determine the creativity of Arabic language teachers in utilizing information technology for distance learning during the covid-19 pandemic. As for some of the media used, such as. Create video content, take advantage of social media, use video conferencing applications such as Zoom and Google Meet, to take advantage of educational website services in the form of Google Classroom and Wordwall games. Based on the results of the analysis conducted by the researchers, this study proved that there are various kinds of teacher creativity in learning Arabic online, such as interactive multimedia, quizzes with google forms, word wall games, and so on. Second, eliminating student learning boredom by developing teacher creativity based on information technology. Third, it is still necessary to conduct information technology-based creativity development training, especially in learning Arabic, because not all Arabic language teachers can develop information technology-based teaching skills. This study proved that there are various kinds of teacher creativity in learning Arabic online, such as interactive multimedia, quizzes with google forms, word wall games. Second, eliminating student learning boredom by developing teacher creativity based on information technology.</span></em><span></span></p><p class="acmparagraph"><em><strong><span>Keywords: </span></strong></em><span>Creativity, Arabic Teacher, Distance Learning, Information Technology.</span></p>
Prognostic significance of non-thyroidal illness syndrome in sepsis and septic shock cases: a systematic review and meta-analysis
Authors: Wironegoro Rio , Kloping Nabila Ananda , Witarto Andro Pramana , Nugraha David , Yogiswara Niwanda , Luke Kevin , Kloping Yudhistira Pradnyan , Maulydia Maulydia , Adi Soebagijo 
Published: February 2022

Background: This study aimed to assess non-thyroidal illness syndrome (NTIS) as a prognostic determinant in patients with sepsis, severe sepsis, and septic shock by evaluating thyroid hormone (TH) levels.
Methodology: A systematic search was performed through electronic databases including PubMed, Embase, Scopus, and Medline. Following medical subject headings (MeSH) and free-text terms: "euthyroid sick syndrome" or "Euthyroid Sick Syndromes" or "non–thyroidal illness syndrome" or "non–thyroidal illness syndrome" or "sick euthyroid syndrome" or "low T3 syndrome" or "low tri-iodothyronine syndrome" AND "sepsis" or "septic shock" or "systemic inflammatory response syndrome" or "septicemia" or "bacteremia". Boolean operators’ combinations were applied to broaden and narrow the search results. Investigators independently reviewed the search results. For the purpose of the meta-analysis each thyroid hormone level was converted into the same unit: nmol/L for T3, T4 and rT3; μIU/mL for TSH; and pmol/L for fT3 and fT4. Statistical analysis was performed using Stata Statistical Software: Release 16. College Station, TX: StataCorp LLC.
Results: A total of 843 patients from 9 studies were included in this analysis. In septic patients, the lowest effect size of thyroid function parameter was TSH (g = 2.05; 95% CI = 1.56-2.54), while T3, fT3, and fT4 had the lowest effect size in severe septic patients (g [95%CI]: 0.83 [0.22-1.44]; 1.92 [0.57-3.27]; 1.00 [0.87-1.13]). Patients with septic shock had the highest effect size of TSH (g = 2.08; 95% CI = 1.54-2.61) and fT4 (g = 9.26; 95% CI = 0.98-17.53). Meanwhile, the lowest was T4 (g = 65.60; 95% CI = 64.63-66.57) and rT3 (g = 0.29; 95% CI = 0.24-0.34). A lower effect size of T3 (g = 0.83; 95% CI = 0.76-0.91), T4 (g = 59.48; 95% CI = 57.92-61.04), fT3 (g = 2.25; 95% CI = 1.83-2.66), and fT4 (g = 9.19; 95% CI = 1.56-16.81) were found in non-survivor groups.
Conclusion: Thyroid hormone levels differ according to the severity of sepsis in septic patients. Non-thyroidal illness syndrome is a prognostic factor in septic patients and is associated with the risk of the mortality.
Abbreviations: ESS - Euthyroid Sick Syndrome; NTIS - Non-Thyroidal Illness Syndrome; Tg - Thyroglobulin
Key words: Non-thyroidal illness syndrome; Euthyroid sick syndrome; Sepsis; Septic shock; Prognosis
Citation: Wironegoro R, Kloping NA, Witarto AP, Nugraha D, Yogiswara N, Luke K, KlopingYP, Maulydia M, Adi S. Prognostic significance of non-thyroidal illness syndrome in sepsis and septic shock cases: a systematic review and meta-analysis. Anaesth. pain intensive care 2021;26(1):54-62.
DOI: 10.35975/apic.v26i1.1768
Received: July 16, 2021, Reviewed: December 15, 2021, Accepted: December 28, 2021
Patterns Among Healthcare Workers of Bangalore About Face Mask Usage: A Single-Center Observational Study
Authors: Mavaji Arun , Raju Umashankar , Kirubakaran Suresh , Khanderi Chinmayee , Hiremath Madhu 
Published: February 2022

ABSTRACT

Introduction
Face masks prevent acute respiratory infections. Healthcare workers are prone to infections owing to their direct and constant exposure to infected patients. This pioneering study in Bangalore city, analyzed the awareness and attitude of healthcare staff toward using a face mask.

Methods
This observational study was conducted among 290 subjects (mean age, 33.89 ± 7.88 years; male:female ratio, 1:2.67). The study included all the healthcare workers from various departments. Data on basic demographic characteristics, attitude, awareness, and observations on the use of face mask were collected.

Results
A large proportion of the sample were from the nursing department (n = 161, 55.51%). Most of the healthcare workers believed that making wearing a mask mandatory in public was very effective (80%) and 79% believed that wearing a mask could prevent the spread of coronavirus. Most of the healthcare workers said they would wear masks even when not mandatory. Most of them used an N95 mask or an N95 mask along with a surgical mask. Almost all were conscious of wearing the mask above the nose, covering the mouth and chin (289, 99.65%). A significantly higher number of doctors (medical postgraduates) (17, 45.95%, p = 0.01) used two masks when compared with others. Significantly fewer doctors (4, 10.81%) and other healthcare staff (8, 22.22%) reused masks (p = 0.002). Most of them used the mask only once, and those who reused it, cleaned it on alternate days (&lt; 0.001). Sun-drying or air-drying, preceded by washing with detergent or soap, were the cleaning methods used, and most used paper or plastic bags to store the masks when not in use. Most of them did not use hand sanitizer before wearing the mask but followed all other precautions and measures to prevent infection.

Conclusions
Most of the healthcare workers believed the use of masks could prevent virus transmission. A significantly higher number of doctors used two masks when compared with other healthcare staff. Significantly fewer doctors and other healthcare staff reused masks when compared with nurses and technicians.
ADVANTAGES OF CREATING A DIGITAL ECOSYSTEM
Authors: Володина Н.Л. 
Published: February 2022

Введение. Статья посвящена исследованию функционирования промышленных предприятий как цифровых экосистем. В статье проанализированы мнения специалистов о содержании цифровой экосистемы и ее ключевых параметрах. Сделан вывод о необходимости структурного управления цифровыми экосистемами. Данные и методы. В статье дано определение понятий экосистемы, цифровой экосистемы как необходимой формой эффективного взаимодействия стейкхолдеров для обеспечения получения выгод и создания ценности, используя цифровые платформы и технологии. При исследовании использовались статистические методы, метод аналогий, данные научных и аналитических публикаций по рассматриваемой проблеме, ресурсы сети интернет. Полученные результаты. Авторами представлена систематизация представлений о экосистемном подходе. В статье выделены отличительные особенности и преимущества реализации цифровой экосистемы. Заключение. Результаты представленного в статье исследования могут быть использованы в качестве теоретической и доказательной базы для принятия решения о создании и функционировании цифровой экосистемы.
Introduction. The article is devoted to the study of the functioning of industrial enterprises as digital ecosystems. The article analyzes the opinions of experts on the content of the digital eco-system and its key parameters. The conclusion is made about the need for structural management of digital ecosystems. Data and methods. The article defines the concepts of ecosystem, digital ecosystem as a necessary form of effective interaction of stakeholders to ensure benefits and value creation using digital platforms and technologies. Statistical methods, the method of analogies, data from scientific and analytical publications on the problem under consideration, and Internet resources were used in the study. The results obtained. The authors present a systematization of ideas about the ecosystem approach. The article highlights the distinctive features and advantages of the implementation of the digital ecosystem. Conclusion. The results of the research presented in the article can be used as a theoretical and evidence base for making a decision on the creation and functioning of a digital ecosystem.
Pengukuran Ketaatan Terapi Anti-Hipertensi Dan Pengaruhnya Terhadap Pasien Diabetes Militus Tipe 2 Menggunakan Metode Pill Count Di Uptd Puskesmas Cilacap Tengah 1
Authors: Nugroho Ikhwan Dwi Wahyu , Restu Amalia  , Yuhansyah Nurfauzi  
Published: February 2022

Diabetes melitus merupakan kelompok penyakit metabolik yang ditandai kondisi hiperglikemia sebagai dampak dari berkurangnya sekresi insulin, menurunnya kinerja insulin atau keduanya. Hipertensi pada pasien diabetes terjadi karena adanya resistensi insulin. Penelitian ini bertujuan untuk mengetahui tingkat ketaatan terapi anti-hipertensi dan pengaruhnya terhadap pasien diabetes militus tipe 2. Metode yang digunakan dalam penelitian ini adalah metode non eksperimen yang bersifat deskriptif dengan pendekatan cross sectional. Penelitian ini dilakukan di UPTD Puskesmas Cilacap Tengah 1. Populasi dalam penelitian ini adalah pasien dewasa prolanis diabetes militus tipe 2 dengan penyakit penyerta hipertensi. Teknik analisis data dalam kegiatan ini disajikan dalam bentuk analisis deskriptif dan analisis bivariat. Pengukuran tingkat kepatuhan menggunakan uji statistik chi square dengan α = 0,05. Dalam menghitung sisa obat menggunakan metode pill count dan kuesioner MGLS untuk mengukur tingkat kepatuhan pasien. Berdasarkan hasil pengukuran tingkat kepatuhan dari 43 responden terdapat 38 responden (88,4%) memiliki tingkat kepatuhan yang patuh dan sebanyak 5 responden (11,6%) memiliki tingkat kepatuhan yang tidak patuh. Pengukuran tingkat kepatuhan menggunakan kuesioner MGLS dari 43 responden terdapat 2 responden (4,7%) memiliki tingkat kepatuhan rendah, 15 responden (34,9%) memiliki tingkat kepatuhan sedang dan 36 responden (60,5%)memiliki tingkat pengetahuan tinggi. Hubungan antara tingkat kepatuhan metode pil count dengan tekanan darah pasien responden di UPTD Puskesmas Kabupaten Cilacap terdapat hubungan ( p value 0,00 < 0,05) dan hubungan antara tingkat kepatuhan metode kuesioner MGLS dengan tekanan darah pasien responden di UPTD Puskesmas Cilacap Tengah 1 terdapat hubungan ( p value 0,01< 0,05)
Penanganan Nasabah Menunggak Kartu Kredit Kolektibilitas Lima Di PT. Muara Toba Persada Bandung
Authors: Widiyaningrum Yunita 
Published: February 2022

Tujuan penelitian ini untuk mengetahui penanganan nasabah kartu kredit, dan cara pembayaran kartu kredit. Penelitian ini secaras pesifik menelaah kegiatan penanganan nasabah yang statusnya sudah mencapai kolektibilitas lima. Dapat mengetahui cara penanganan nasabah dengan pihak bank, kemudian peneliti dapat memahami prosedur yang ada di PT. Muara Toba Persada. Selama proses penanganan nasabah bermasalah dalam kartu kredit , penulis mendapat hasil yang cukup dapat di pahami dengan beberapa kegiatan di dalam nya. Penulis melakukan kegiatan Penginputan Data Nasabah bulan Juli, Agustus dan September. Kemudian penulis melakukan Komunikasi kepada Nasabah terhadap Penagihan langsung melalui telepon dan, mencari tau lewat Media Sosial seperti Facebook, instagram dan lain-lain. Adapun cara pembayaran yang bisa nasabah gunakan dengan cara datang langsung ke kantor BRI terdekat atau dengan cara di transfer menggunakan atm BRI terdekat, dengan cara : Pilih menu transaksi lain, pilih menu pembayaran, pilih menu kartu kredit, pilih menu BRI, masukkan 16 angka nomor kartu kredit, pilih YA pada menu untuk melanjutkan transaksi, masukkan jumlah pembayaran yang sudah ada, pilih YA, pada menu konfirmasi pembayaran
The Effects of Stellar Gravity Darkening on High-resolution Transmission Spectra
Authors: Cauley P. Wilson , Ahlers John P. 
Published: February 2022

Abstract
High-resolution transmission spectroscopy is a powerful method for probing the extended atmospheres of short-period exoplanets. With the advancement of ultrastable echelle spectrographs and the advent of 30 m class telescopes on the horizon, even minor observational and physical effects will become important when modeling atmospheric absorption of atomic species. In this work we demonstrate how the nonuniform temperature across the surface of a fast rotating star, i.e., gravity darkening, can affect the observed transmission spectrum in a handful of atomic transitions commonly observed in short-period exoplanet atmospheres. We simulate transits of the ultrahot Jupiters KELT-9 b and HAT-P-70 b but our results are applicable to all short-period gas giants transiting rapidly rotating stars. In general, we find that gravity darkening has a small effect on the average transmission spectrum but can change the shape of the absorption light curve, similar to the effect observed in broadband photometric transits. While the magnitude of gravity-darkening effects are on the same order as the noise in transmission spectra observed with 10 m class telescopes, future high-quality spectroscopic light curves for individual atomic absorption lines collected with 30 m class telescopes will need to account for this effect.