bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhancing the collective, protecting the personal: the valuable role of composite narratives in medical education research
Authors: McElhinney Zoë , Kennedy Catherine 
Published: August 2022

Narrative research approaches provide the opportunity for constructing a detailed understanding of lived experiences relevant to medical education, in areas such as illness narratives, explorations of doctor-patient relationships, and the development of professional identities in students and educators. The benefits of the depth of data gathered in narrative research are, however, counterbalanced by possible weaknesses relating to a focus on individual cases and the risk of identification of participants where subjects are sensitive or unique. To address these concerns, researchers from a variety of social science disciplines, carrying out research employing a range of methodological approaches, have begun to use ‘composite narratives’ in which the commonalities in the experiences of research participants are combined to create joint narrative or narratives which illustrate participants’ shared experiences. Composite narratives have been used both as a component of the methodological approach and as a method of presenting the results of research in a variety of methodologies. This A Qualitative Space paper explores the role, strengths, and weaknesses of narrative research, before outlining the ways in which composite narrative has been defined within existing research. Distinctions between the various approaches to creating composite narratives are discussed, highlighting the differences in the types of data utilised, and the approaches taken to data analysis and presentation. A key distinction is identified between the use of composite narratives as part of an integrated methodology and as an approach to the presentation of data. Finally, issues relating to trustworthiness, reflexivity, and implications for researchers are considered.
The OPTIMISE study protocol: a multicentre optimisation trial comparing continuous glucose monitoring, snacking habits, sleep extension and values-guided self-care interventions to improve glucose time-in-range in young people (13–20 years) with type 1 diabetes
Authors: Rose Shelley , Haszard Jillian J. , Galland Barbara C. , Wiltshire Esko J. , de Bock Martin I. , Smart Carmel E. , Ketu-McKenzie Miriama , Campbell Anna , Thomson Ruth , Jefferies Craig A. , Wheeler Benjamin J. , Styles Sara E. 
Published: August 2022

Abstract
Purpose
The OPTIMISE study uses a Multiphase Optimisation Strategy (MOST) to identify the best combination of four interventions targeting key diabetes self-care behaviours for use in clinical practice to improve short-term glycaemic outcomes.

Methods
This 4-week intervention trial will recruit 80 young people (aged 13–20 years) with type 1 diabetes ≥ 6 months duration), and pre-enrolment HbA1c ≥ 58 mmol/mol (7.5%) in the prior 6 months. Both main intervention and interaction effects will be estimated using a linear regression model with change in glucose time-in-range (TIR; 3.9–10.0 mmol/L) as the primary outcome. Participants will be randomised to one of 16 conditions in a factorial design using four intervention components: (1) real-time continuous glucose monitoring (CGM), (2) targeted snacking education, (3) individualised sleep extension, and (4) values-guided self-care goal setting. Baseline and post-intervention glucose TIR will be assessed with blinded CGM. Changes in self-care (snacking behaviours, sleep habits and duration, and psychosocial outcomes) will be assessed at baseline and post-intervention to determine if these interventions impacted behaviour change.

Discussion
The study outcomes will enable the selection of effective and efficient intervention components that increase glucose TIR in young people who struggle to achieve targets for glycaemic control. The optimised intervention will be evaluated in a future randomised controlled trial and guide the planning of effective clinical interventions in adolescents and young adults living with type 1 diabetes.

Trial registration
This trial was prospectively registered with the Australian New Zealand Clinical Trials Registry on 7 October 2020 (ACTRN12620001017910) and the World Health Organisation International Clinical Trails Registry Platform on 26 July 2020 (Universal Trial Number WHO U1111-1256-1248).
Empirical Evidence for the Continuing Need to ‘Think Small First’ in UK Company Law
Authors: Hardman Jonathan , Ramírez Santos Guillem 
Published: August 2022

AbstractThe most recent UK corporate law restatement has its stated aim to ‘think small first’ in company law legislation. This article is the first to use data science and imaging techniques to provide an empirical snapshot of the entire UK corporate database. It identifies the continuing need to think small first: most companies are small when tested by corporate type (public v private) and type of accounts publicly filed. We then factor in time series, which evidences that most companies are newer and smaller companies. This article then identifies the implications of this novel empirical analysis. First, corporate law analysis tends to ‘think big first’, and will either need to justify such an approach or change it. Second, a large number of companies provide no public financial information due to inherent time lag. The sheer scale of new companies challenges this approach. Third, the UK should provide a corporate governance framework for smaller companies. Fourth, the UK’s corporate accounting regime thinks small first in substance, but its form needs to be simplified to truly think small first. Fifth, whilst more mortgages were granted by smaller companies, larger companies granted more mortgages per company: so arguably corporate finance bucks the trend for the need to think small first.
A Simplified Method for RNA Isolation from Biofabricating Hydroxyapatite Scaffolds and Identification of Appropriate Reference Genes
Authors: Wang Qian , Wang WenTao , Zhang PengHui , Zhou ZhiYu , Li Tian , Li JianFeng , Canavese Federico , Gao ManMan 
Published: August 2022

Abstract
Purpose
To validate a simplified RNA isolation method from biofabricating hydroxyapatite (HAp) scaffolds seeded with mesenchymal stem cells (MSCs) and to identify the appropriate reference gene.

Methods
Ten MSCs-HAp composites were used for RNA isolation by methods based on simplified homogenization steps and column-based purification procedures, while the remaining RNA (n = 13) was extracted by traditional single-step isolation methods. The differences between the two procedures regarding the operation time, RNA quantity and quality were evaluated. Quantitative real-time PCR (qRT-PCR) analysis was performed to identify the appropriate reference gene.

Results
The simplified method showed significant superiority in operation time (P < 0.001), RNA concentration (P < 0.001), A260/280 ratio (P = 0.005) and A260/230 ratio (P < 0.001). The average integrity number and 28 s/18 s ratio of RNA yielded by the simplified method were 9.1 ± 0.2 and 1.3 ± 0.1, respectively. The qRT-PCR analysis results indicated that the cycle threshold (Ct) values of GAPDH were significantly higher than those of the remaining 2 reference genes (ACTB and RPL13A) in the RNA samples obtained by the simplified and traditional methods (P < 0.05). The standard deviations of the ΔCt value (the difference between the Ct value and the minimum) of ACTB were higher than those of GAPDH or RPL13A, regardless of the RNA isolation method.

Conclusion
The simplified method could extract intact RNA from biofabricating MSCs-HAp scaffolds and was superior to the traditional single-step procedure in operation time, RNA quantity and quality. GAPDH was identified as the most appropriate reference gene in MSCs-HAp scaffold composites due to its high quantity and good stability.
Relating Siegel cusp forms to Siegel–Maaß forms
Authors: Kramer Jürg , Mandal Antareep 
Published: August 2022

AbstractIn this paper we generalize a well-known isomorphism between the space of cusp forms of weight k for a Fuchsian subgroup of the first kind $$\Gamma \subset \mathrm {SL}_{2}({\mathbb {R}})$$

Γ
⊂

SL
2

(
R
)

and the space of certain Maaß forms of weight k for $$\Gamma $$
Γ
to an isomorphism between the space of Siegel cusp forms of weight k for a subgroup $$\Gamma \subset \mathrm {Sp}_{n}({\mathbb {R}})$$

Γ
⊂

Sp
n

(
R
)

, which is commensurable with the Siegel modular group $$\mathrm {Sp}_{n}({\mathbb {Z}})$$

Sp
n

(
Z
)

, and a suitable space of Siegel–Maaß forms of weight k for $$\Gamma $$
Γ
.
Covalent and Non-covalent Functionalized Nanomaterials for Environmental Restoration
Authors: Zhang Shizhong , Malik Sumeet , Ali Nisar , Khan Adnan , Bilal Muhammad , Rasool Kashif 
Published: August 2022

AbstractNanotechnology has emerged as an extraordinary and rapidly developing discipline of science. It has remolded the fate of the whole world by providing diverse horizons in different fields. Nanomaterials are appealing because of their incredibly small size and large surface area. Apart from the naturally occurring nanomaterials, synthetic nanomaterials are being prepared on large scales with different sizes and properties. Such nanomaterials are being utilized as an innovative and green approach in multiple fields. To expand the applications and enhance the properties of the nanomaterials, their functionalization and engineering are being performed on a massive scale. The functionalization helps to add to the existing useful properties of the nanomaterials, hence broadening the scope of their utilization. A large class of covalent and non-covalent functionalized nanomaterials (FNMs) including carbons, metal oxides, quantum dots, and composites of these materials with other organic or inorganic materials are being synthesized and used for environmental remediation applications including wastewater treatment. This review summarizes recent advances in the synthesis, reporting techniques, and applications of FNMs in adsorptive and photocatalytic removal of pollutants from wastewater. Future prospects are also examined, along with suggestions for attaining massive benefits in the areas of FNMs.
Snoring and aortic dimension in Marfan syndrome
Authors: Sowho Mudiaga , Potocki Mariah , Sgambati Frank , Neptune Enid 
Published: August 2022

AbstractRecent reports suggest that self-reported snoring, which is a feature of obstructive sleep apnea, is associated with aortic enlargement in Marfan syndrome (MFS). Objective assessment of snoring although lacking, could provide a rational for OSA screening in MFS patients. Our goal in this study was to examine the association between objective measurements of snoring with OSA and aortic size in persons with MFS. Consecutive persons with MFS who reported snoring were recruited at Johns Hopkins, completed the Epworth Sleepiness Scale (ESS) and underwent overnight polysomnography during which inspiratory sound was captured. We measured breath-by-breath peak decibel levels and snoring was defined as flow limitation with sound ≥ 40 dB(A). OSA was defined as an apnea–hypopnea-index (AHI) ≥ 15 or AHI: 5–15 and ESS > 10. Participants’ aortic data were collated to ascertain aortic root diameter. Regression models were used to determine the relationship of snoring breath% with OSA and aortic root diameter. In our cohort (M|F:13|16, Age: 37.0 ± 15.5 years, Aortic diameter; 38.9 ± 4.8 mm), a 1-unit increase in snoring breath percentage increased the odds of having OSA by 5% in both the unadjusted (OR = 1.05, p = 0.040) model, and a model adjusted for age and sex (OR = 1.05, p = 0.048). Similarly, a 10-unit increase in snoring breath percentage was associated with a 1 mm increase in contemporaneous aortic-root-diameter in both unadjusted (β = 0.09, p = 0.007), and adjusted (β = 0.08, p = 0.023) models. Objective snoring assessment could provide a means for identifying persons with MFS who need sleep studies, who may also be at risk for more severe aortic disease.
Rationalism in Politics
Authors: Steinberger Peter J. 
Published: August 2022

Arguing against emergent and even dominant tendencies of recent political thought that emphasize the so-called primacy of affect, Peter Steinberger challenges political theorists to take account of important themes in philosophy on the topic of human rationality. He engages with major proponents of post-Kantian thought, analytic and continental alike, to show how political judgment and political action, properly understood, are deeply and definitively grounded in considerations of human reason. Focusing especially on influential arguments in the philosophy of mind and the philosophy of action, he seeks to rediscover and reanimate the close connection between systematic philosophical speculation on the one hand and the theory and practice of politics on the other. The result is a neo-rationalist conception of judgment and action that promises to offer a substantial and compelling account of political enterprise as it plays out in the real world of public affairs.
Rebuilding the foundation of late Paleozoic pinnid bivalve study (family Pinnidae)
Authors: Yancey Thomas E. , Amler Michael R. W. , Raczyński Paweł , Brandt Silvio 
Published: August 2022

AbstractThe early geologic history of family Pinnidae, a diverse and abundant component of mud-dominated shallow marine environments of the late Paleozoic, is obscured by ill-defined genus and species concepts. Mistakes in descriptions and reconstructions have provided a basis for suggestions that older taxa in the family differ from younger taxa and may not belong in family Pinnidae. This report provides improved documentation that removes the basis for the concept of divergence. Late Paleozoic genera and species have definite pinnid bivalve characters, including a dorsomarginal fold that holds the ligament, a thick outer columnar prismatic shell layer, and an equivalved, triangular shell, all of which provide evidence for confident assignment of the genus to family Pinnidae. The suggested synonymy of Aviculopinna with Pteronites is invalid, and genus Aviculopinna is limited to occurrence in Permian strata. The two genera belong in different families. A neotype is designated for genus Aviculopinna type species Aviculopinna pinnaeformis Geinitz from Gera, Germany, and a lectotype for Aviculopinna neukirchensis Langenhan from Nowy Kościół, Poland. Inferences on the life habits of Aviculopinna based on its occurrence in Poland are presented. An evaluation of the subterminal beak versus terminal beak concept in pinnids is presented and conclusion presented that there are few data available to support the concept or to test it. In its present form, the concept has no utility in the study of pinnid bivalves.
The sweet tooth of infancy: Is sweetness exposure related to sweetness liking in infants up to 12 months of age?
Authors: Müller Carina , Chabanet Claire , Zeinstra Gertrude G. , Jager Gerry , Schwartz Camille , Nicklaus Sophie 
Published: August 2022

AbstractInfants become increasingly exposed to sweet-tasting foods in their first year of life. However, it is still unclear whether repeated exposure to sweet taste is linked to infants’ sweetness liking during this period. Making use of data from the OPALINE cohort, this study aimed to examine the link between sweetness exposure and sweetness liking during two important periods in early infant feeding: at the start of complementary feeding (3–6 months) and the transition to the family table (10–12 months). Infants’ sweetness exposure was assessed using 7-d food records which were completed by mothers every month (n 312), reporting daily consumption rates of formula/breast milk or complementary food and the type of formula milk and/or complementary foods for each feeding occasion. Infants’ sweetness liking was studied in the laboratory at 3, 6 and 12 months of age by assessing their response to a lactose–water solution and the amount drunk of this solution compared with plain water. Linear regressions and structural equation model assessed associations between exposure to and liking for sweetness at 6 and 12 months. Neither at 6 (n 182) nor at 12 months (n 197) was sweetness exposure associated with sweetness liking. While sweetness liking at 3 months was unrelated to liking at 6 months, the latter predicted sweetness liking at 12 months. These findings demonstrate no association between sweetness exposure at 3 to 12 months and liking at 6 and 12 months despite a sharp increase in sweetness exposure in that period. However, sweetness liking at 6 and 12 months was positively associated.
Spatial Projects of Forgetting: Razing the Remedies Church and Museum to the Enslaved in São Paulo's ‘Black Zone’, 1930s–1940s
Authors: Britt Andrew G. 
Published: August 2022

AbstractIn the shadows of a Shinto torii (gateway) in São Paulo's ‘Japanese’ neighbourhood rests the city's first burial ground for enslaved Africans. Recently unearthed, the gravesite is one of the few visible remains of the Liberdade neighbourhood's significance in São Paulo's ‘Black zone’. This article excavates the history of the nearby Remedies church, the headquarters of Brazil's Underground Railroad and a long-time museum to the enslaved. The 1942 demolition of the Remedies church, I argue, comprised part of a spatial project of forgetting centred on razing the city's ‘Black zone’ and reproducing São Paulo as a non-Black, ethnically immigrant metropolis.
High haemoglobin levels at the time of occlusion predict worse outcome for patients with patent ductus arteriosus and pulmonary hypertension
Authors: Kishi Kanta , Jarutach Jirayut , Ooi Yinn Khurn , Wong Ngie Liong , Che Mood Marhisham , Kandhavello Geetha , Alwi Mazeni , Leong Ming Chern 
Published: August 2022

AbstractIntroduction:Current guidelines discourage shunt closure in patients with pulmonary vascular resistance index >8 Wood units x m2. The study examined the long-term outcome of patients over 15 years old, with pulmonary vascular resistance index >8 Wood units x m2 and patent ductus arteriosus.Materials and methods:This was a multi-institutional, retrospective study involving all consecutive patients (>15 years old) with patent ductus arteriosus and severe pulmonary hypertension. Patients who had patent ductus arteriosus closure were divided into the Good (no death or hospital admissions due to worsening pulmonary hypertension) and the Poor Outcome groups and these groups were compared.Results:Thirty-seven patients [male: 9 (24.3%); mean age: 30.49 ± 9.56 years; median follow-up: 3 (IQR: 1.5,10) years] were included from four centers. Twenty-two patients who underwent patent ductus arteriosus closure, 15 (71.4%) had good outcomes while 7 (28.6%) had poor outcomes. Pulmonary vascular resistance index and pulmonary to systemic resistance ratio (Rp:Rs) were lower in the Good Outcome Group (14.35 ± 1.66 Wood units x m2 vs. 20.07 ± 2.44; p = 0.033 and 0.44 ± 0.16 vs. 1.08 ± 1.21; p = 0.042). Haemoglobin concentrations (<14.3 g/dL) were associated with good long-term outcomes in the Closed Group.Conclusions:Patients with patent ductus arteriosus with severe pulmonary hypertension have a dismal outcome with or without closure. High haemoglobin levels at the time of occlusion predict a worse outcome for patients with patent ductus arteriosus and pulmonary hypertension.
Do Gladiators Fight for Their Masters? Voting Behavior of the US-Promoted United Nations Security Council Members in the Early Cold War
Authors: Balci Ali 
Published: August 2022

ABSTRACTThe United States took an active role in promoting some countries for a United Nations Security Council seat as part of its struggle with the Soviet Union during the early Cold War. Did these US-backed countries act in the interests of their promoter when they voted in the Council? Were these efforts of the United States advantageous? By studying the voting behavior of the US-backed countries between 1946 and 1965, this article answers the question of whether promoting some states to international institutions is beneficial for the great powers.
Mislearning and (poor) performance of individual investors
Authors: Villatoro Félix , Fuentes Olga , Riutort Julio , Searle Pamela 
Published: August 2022

AbstractWe study individuals' incentives to make investment decisions. Using data from a large pension system in Chile we find that individuals who are active in managing their investments have, on average, poor performance. We provide robust evidence suggesting that learning plays an important part in this phenomenon. Indeed, individuals who have made successful investment decisions in the past go on to trade more frequently. However, this result holds when using a naive definition for successful decisions. Also, average performance is negatively related to the number of investment decisions, casting doubt on the existence of market timing skills.
A Short‐Term Regional Precipitation Prediction Model Based on Wind‐Improved Spatiotemporal Convolutional Network
Authors: Qiu Yunan , Lu Zhenyu , Tang Haibo 
Published: August 2022

AbstractAccurate precipitation prediction can help decision makers judge the trend of climate change and formulate more effective measures, and prevent flood and drought disasters. In this paper, we propose a short‐term regional precipitation prediction model based on wind‐improved spatiotemporal convolutional network. Among them, the improved graph convolution network integrates the effects of wind direction and geographic location at past moments to capture the spatial dependence, whilst the gated recurrent unit captures the temporal dependence by learning the dynamic changes of data. The spatio‐temporal memory flow module and attention module are added to capture spatial deformation and temporal variation more accurately, thereby better matching the physical properties of precipitation. The proposed model achieves better prediction results on real data sets. Experiments show that our method is better at extracting the spatio‐temporal information of precipitation data and capturing its time dependence and spatial correlation.
Constraints on the Magma Source and Rift Evolution From Geochemistry of the Stratoid Flood Basalts (Afar, Ethiopia)
Authors: Tortelli G. , Gioncada A. , Pagli C. , Braschi E. , Gebru E. F. , Keir D. 
Published: August 2022

AbstractThe relationship between rifting and continental flood basalt eruptions is debated, and a control by mantle plume is commonly invoked for flood basalts production. In this work, we investigate the relationship between magmatism and rifting by studying the flood basalts erupted in Afar (4.5–0.6 Ma), known as the Stratoid and Gulf Series. We present new field observations and petrography, major and trace elements analyses and mineral chemistry of lavas collected during a regional campaign in Afar. The Series are characterized by E‐MORB magmatism and residual amphibole in the mantle source, consistent with the contribution of metasomatized sub‐continental lithospheric mantle during partial melting. Differences in garnet‐compatible elements indicate a shallower melting column for the oldest and youngest products (4.5–2.6 Ma Lower Stratoid Series; 1.1–0.6 Ma Gulf Series), and deeper for the products erupted at 2.6–1.1 Ma (Upper Stratoid Series). Incompatible element ratios (Th/Nb, Th/Zr) indicate a higher degree of partial melting for the Gulf with respect to the Upper Stratoid Series. Accordingly with independent geophysical and stratigraphic evidence, we explain our results with rift re‐localization: the Pliocene rift caused thinning of the lithosphere and the Lower Stratoid eruptions in Southern Afar, then the Pleistocene rift jumped to Central Afar under a less‐extended lithosphere, producing the Upper Stratoid and, subsequently, as stretching of the lithosphere localized, the Gulf Series formed. Our findings suggest that rift migration and localization can exert a fundamental control on the spatial variability and character of flood basalts without requiring variations on the activity of the mantle plume.