bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aportes de la biotecnología en el diagnóstico de COVID-19
Authors: Carlucci Adriana M. , Antonelli Camila E. , Ermocida Juan C. , Raventos Sofía C. , Sterin Prync Aída E. 
Published: October 2022

Introducción: en diciembre del año 2019 surgió en China una neumonía viral; el virus fue identificado como un coronavirus SARS-CoV-2, que se propagó rápidamente de tal manera que se convirtió en pandemia. La alta contagiosidad y la presencia de portadores asintomáticos dificultaron el diagnóstico de la infección y la toma de decisiones sanitarias.
Objetivo: el objetivo de esta revisión bibliográfica es presentar y describir las principales técnicas utilizadas actualmente para el diagnóstico de COVID-19 y establecer su relación con los conocimientos de distintas disciplinas y tecnologías emergentes que confluyen en la Biotecnología bioquímico-farmacéutica orientada a la Salud humana.
Metodología: se realizó una revisión de la bibliografía disponible en PubMed a partir de enero de 2020 sobre las pruebas diagnósticas que se encuentran actualmente en uso, en el ámbito sanitario, para la detección y seguimiento de la enfermedad COVID-19. También se realizaron búsquedas a través de Google y Google Académico para publicaciones de organismos de Salud en referencia a métodos diagnósticos.
Resultados: se presenta una importante cantidad de pruebas diagnósticas, basadas en diferentes tecnologías, que desempeñan un papel clave en la pandemia de COVID-19. Algunas de ellas muy sofisticadas, como la secuenciación genómica de próxima generación, otras más estándar, pero igualmente robustas, como la reacción en cadena de la polimerasa (PCR). También otras adaptadas para el brote pandémico, como la amplificación isotérmica de ácidos nucleicos mediada por bucle. Todas las mencionadas se consideran de tipo molecular, pero también existen las pruebas serológicas, como ELISA, que incluyen ensayos en plasma o de tipo inmunológico. Estas sirven para detectar anticuerpos frente a la exposición al virus o antígenos en personas potencialmente infectadas.
Conclusiones: los procesos de investigación y desarrollo biotecnológicos aplicados al diagnóstico y los conocimientos científicos previos permitieron una respuesta tanto nacional como internacional rápida y eficaz en medio de una inédita pandemia global. En esta revisión destacamos las principales técnicas, en qué estadio se deben usar y qué información nos aportan.
PENGARUH KEPEMIMPINAN DAN LINGKUNGAN KERJA TERHADAP KEPUASAN KERJA KARYAWAN SMK PGRI 5 DENPASAR
Authors: Sujana I Made 
Published: October 2022

Tujuan dari penelitian ini adalah untuk mengetahui dan menganalisis pengaruh antara variabel kepemimpinan dan lingkungan kerja secara bersama-sama terhadap kepuasan kerja karyawan SMK PGRI 5 Denpasar. Selain itu, untukengetahui pengaruh antara variabel kepemimpinan dan lingkungan kerja secara parsial terhadap kepuasan kerja karyawan SMK PGRI 5 Denpasar.
Penelitian ini merupakan penelitian ekspalanatory Populasi dalam penelitian adalah seluruh karyawan di SMK PGRI 5 Denpasar sebanyak 73 orang Teknik pengambilan sampel yang digunakan pada penelitian ini adalah sensus sampling yaitu pengambilan sampel yang diambil seluruh anggota populasi. Pada penelitian ini sampel penelitian sebanyak 73 responden Pengumpulan data dalam penelitian ini menggunakan kuesioner dan studi dokumentasi. Metode analisis dalam dalam penelitian ini terbagi menjadi 2 (dua), yaitu analisis deskriptif dan analisis regresi berganda.
Hasil analisis data menunjukkan bahwa kepemimpinan dan lingkungan kerja secara bersama-sama berpengaruh terhadap kepuasan kerja karyawan pada SMK PGRI 5 Denpasar. Pengaruh Kepemimpinan dan Lingkungan kerja tersebut pada kepuasan kerja karyawan sebesar 46,3%, oleh karena itu kepuasan kerja karyawan sebesar 53,7% dipengaruhi oleh variabel lain. Secara parsial kepemimpinan dan lingkungan kerja berpengaruh signifikan positif terhadap kepuasan kerja karyawan pada SMK PGRI 5 Denpasar.
The Reamer-Irrigator-Aspirator (RIA) System for the treatment of aseptic femoral nonunions: Report of two cases and literature review.
Authors: Landrino Marco , Alberio Riccardo Luigi , Clemente Alice , Grassi Federico Alberto 
Published: October 2022

Femoral shaft nonunions are disabling complications of fractures, with relevant socioeconomic and psychological impact. The incidence of femoral shaft nonunions is not negligible, ranging between 1% and 10% after intramedullary nailing, but can exceed 20% in case of subtrochanteric fractures. Treatment options are influenced by pathomechanical, anatomical, and clinical factors. Hypertrophic nonunions are usually treated by enhancing stability of fixation, while atrophic nonunions require additional biological stimulation to achieve bone union. The Reamer-Irrigator-Aspirator (RIA) System® was developed to reduce intramedullary pressure and heat generation during intramedullary reaming, thus preventing thermal necrosis and decreasing the risk of fat embolism. The RIA System allows to provide large volumes of high-quality morselized autologous bone, that has shown high osteogenetic and osteoinductive properties. Therefore, its use has been expanded as a valuable source of autologous bone graft for the treatment of large bone defects of different nature. In this article, we present two cases of complex femoral nonunions treated with the use of the RIA System. A review of the published literature on the treatment of femoral nonunions with RIA was also performed. Core tip: In case of atrophic nonunions, the RIA System can be used to obtain biologically active tissue to enhance bone healing. Despite the absence of high-quality studies focused on femoral nonunions, the efficacy of RIA is well-known and orthopaedic surgeons should be aware of this powerful tool.
Sobre el canto mágico, las perspectivas sonoras, las multinaturas ambientales y la experiencia consciente
Authors: Brabec de Mori Bernd 
Published: October 2022

Hasta ahora la importancia de lo sónico, especialmente la música vocal, en el contexto del animismo y el perspectivismo ha sido subestimada en la teoría antropológica. Basandose en ejemplos de canciones mágicas de los shipibo-konibo extraídas de grabaciones etonomusicológicas propias del trabajo del campo del autor, se propone en este artículo que la experiencia en primera persona de médicos (curanderos o brujos) debe ser considerada de altísimo valor para la interpretación de las estructuras de ralaciones entre humanos y no humanos. Esta experiencia surge de manera más evidente en los estilos de canto y las letras de las canciones interpretadas por los médicos en el estado de interacción con los no humanos durante la curación, la adoración o la lucha rituales. Los resultados obtenidos de este análisis incluyen...
STATE AND LOCAL GOVERNMENT IN TERMS OF INTERACTION: HISTORICAL AND SOCIOLOGICAL PERSPECTIVES (ARTICLE 1)
Authors: Иваненко Игорь Николаевич 
Published: October 2022

Настоящая статья посвящена рассмотрению сущности государства в качестве социально-исторического явления, что способствует углублению понимания процессов политогенеза как фактора влияния на динамику структур местного самоуправления. Точка зрения автора базируется на стыке либерального, консервативного и марксистского подходов, каждый из которых раскрывает определенную значимую характеристику высшей власти. На основе операционализации понятия «государство» выявляются эволюционные механизмы взаимодействия государства и общества. Констатируется двойственная природа государства, которое в собственных действиях подвержено детерминации со стороны правящего класса, а также общенациональных интересов. Делается заключение о сущностной противоречивости государства. Так, с одной стороны, внутренне присущий любому государству «властный инстинкт» инициирует стремления к контролю «сверху» за максимально расширенным кругом общественных отношений, а с другой стороны, условия социальной действительности в той или иной степени ограничивают подобные стремления. Второе обстоятельство в полной мере относится к феномену местного самоуправления, который формирует автаркийную природу общественных отношений и накладывает на граждан особую ответственность в выборе социального действия
This paper deals with the essence of the state as a socio-historical phenomenon, which contributes to the deepening of the understanding of the processes of polytogenesis as a factor of influence on the dynamics of local self-government structures. The author's point of view is based on the intersection of liberal, conservative and Marxist approaches, each of which reveals a certain significant characteristic of higher power. On the basis of operationalization of the concept of "state," evolutionary mechanisms of interaction between the state and society are developed. The dual nature of the state is stated, which in its own actions is subject to determination by the ruling class, as well as national interests. A conclusion is made about the essential inconsistency of the state. So, on the one hand, the "power instinct" inherent in any state initiates aspirations for control "from above" over the most expanded circle of social relations, and on the other hand, the conditions of social reality to one degree or another limit such aspirations. The second circumstance fully relates to the phenomenon of local self-government, which forms the autarky nature of social relations and imposes on citizens a special responsibility in choosing social action
EXPERT ASSESSMENT OF THE LEVEL OF TRUST IN THE AUTHORITIES IN THE ADYGHEA REPUBLIC AND KRASNODAR TERRITORY AND ITS STRENGTHENING TECHNOLOGY
Authors: Ильинова Надежда Александровна , Куква Елена Сергеевна , Киреева Ирина Владимировна 
Published: October 2022

В статье представлены результаты опроса экспертного сообщества Республики Адыгея и Краснодарского края, нацеленного на выявление барьеров на пути реализации управленческих технологий формирования доверия населения к власти и определение наиболее эффективных путей его повышения в условиях распространения COVID-19. В настоящее время доверие к власти не сформировано в полной мере. Барьеры в деле повышения доверия населения к власти определяются сочетанием комплекса факторов, наиболее значимыми из которых, по мнению экспертного сообщества исследуемых нами национальных регионов, являются: отсутствие понимания у населения действий властей, даже тех, которые направлены на улучшение жизни населения; отсутствие системы применения мер, направленных на повышение доверия к власти у населения; равнодушие власти к инициативам населения; «двойные» стандарты и переизбыток прав и свобод. Причины недоверия, которое, по мнению экспертов, приводит к росту распространения пандемии, содержатся, прежде всего, в коммуникационном разрыве. Соответственно, на первый план выходят управленческие технологии, реализуемые посредством применения инструментов, позволяющих обеспечить население своевременной, полной, достоверной информацией о направлениях и результатах деятельности органов исполнительной власти в доступной и понятной форме, а также создающие основу для диалога власти и общества
The paper presents the results of the expert community survey in the Adyghea Republic and Krasnodar Territory, aimed at identifying barriers to the implementation of management technologies for building public confidence in the authorities and determining the most effective ways to increase it in the context of the spread of COVID-19. Currently, confidence in the authorities has not been fully formed. Barriers to increasing public confidence in power are determined by a combination of a set of factors. The most significant of them, according to the expert community of the national regions we study, are: the population's lack of understanding of the authorities’ actions, even those aimed at improving the life of the population; lack of a system of measures aimed at increasing public confidence in power; indifference of the authorities to the initiatives of the population; "double" standards and an overabundance of rights and freedoms. The reasons for the distrust, which, according to experts, leads to an increase in the spread of the pandemic, are contained, first of all, in the communication gap. Accordingly, management technologies, implemented through the use of tools that provide the population with timely, complete, reliable information on the directions and results of the activities of executive authorities in an accessible and understandable form, as well as creating the basis for dialogue between the authorities and society, come to the fore
Determinants Dividen Payout Ratio and Its Impact on Decitions Investment: A cas study on a mining company listed in Indonesia Stock Exchange
Authors: Maria Ulfa  , Salim Mohammad Noor 
Published: October 2022

Purpose – This study aims to analyze the effect of financial performance on investment decisions with dividend policies (DPR) as intervening variables in mining sector companies listed on the Indonesia Stock Exchange for 2017 to 2020. The independent variables used in this study are financial performance. The financial performance used in this study is Return on Asset (ROA), Current Ratio (CR), Debt to Equity Ratio (DER), Free Cash Flow (FCF), and Dividend Policy (DPR), while the dependent variable is investment decision ( IOS). This study aims to analyze the effect of financial performance on investment decisions with dividend policies (DPR) as intervening variables in mining sector companies listed on the Indonesia Stock Exchange for 2017 to 2020. The independent variables used in this study are financial performance. The financial performance used in this study is Return on Asset (ROA), Current Ratio (CR), Debt to Equity Ratio (DER), Free Cash Flow (FCF), and Dividend Policy (DPR), while the dependent variable is investment decision ( IOS).
Methodology/approach – The sample in this study consisted of 13 mining sector companies listed on the Indonesia Stock Exchange (IDX) in the 2017 to 2020 period which was selected based on certain criteria using the purposive sampling method. Analysis of the data used in this study is a multiple Liniear regression analysis (T test and F test) which is processed using Eviews 11.0.
Findings – It was found that . the multiple regression models used in this study, the results of partial testing (T test) showed that only two variables namely ROA, and DER with probability of 0.0006 and the most dominant tstatistics were 3,694806 and inflation rates that had a significant effect on investment decisions. In addition, simultaneously (F test) shows that ROA, CR, DER, FCF, jointly affects investment decisions.
Novelty/value – Since dividend policy affects investment decisions, it is very important to know the factors that influence dividend policy. Keywords Employee Dividen Payout Ratio, Investment, Dividen Policy
Good Corporate Governance At Basic Industry and Chemical Company Affecting Profitability in Review from the Aspect of Earning Per Share
Authors: Nasfi Nasfi 
Published: October 2022

The purpose of this study was to determine the effect of institutional ownership to determine the effect of board size partially, to determine the effect of the composition of commissioners partially to the company's profitability as proxied by Earning Per Share and to determine the effect of the number of audit committees partially to profitability as proxied by Earning Per Share.
The research method uses a purposive sampling technique with a representative sample of 45 companies engaged in the basic industry and chemical sector listed on the Indonesia Stock Exchange from 2018 to 2021, data processing analysis with descriptive statistical analysis with panel data estimation of engineering models. and presented in qualitative and quantitative forms.
Institutional Ownership has a coefficient value of -0.468 and a p-value t-stat of 0.298 which means it has a negative and insignificant effect, the Board of Directors has a coefficient value of -0.044 and a p-value t-stat of 0.904 which means a negative effect and not significant, the Independent Commissioner has a coefficient value of 0.647 and a p-value t-stat of 0.0000 which means a positive and significant effect and the Audit Committee has a coefficient value of -1.0289 and a p-value of t-stat 0, 0000 which means negative but significant.
The novelty of this study is the existence of a partial audit committee variable from other studies.
INCREASING STUDENTS WRITING USING SERIES PICTURE AT MA MIFTAHUL ULUM CERMENAN JOMBANG
Authors: Khudriyah Khudriyah 
Published: October 2022

The research aimed to describe how series picture is able to improve the students writing ability of Eleventh students of MA Miftahul Ulum Cermenan Jombang. the researcher conducted action research by four stages: planning, implementing, observing, and reflecting. The subjects of the research were 30 students of the eleventh grade of MA Miftahul Ulum Cermenan Jombang in 2021/2022 academic year. This study was implemented in two cycles. Each cycle consisted of four meetings. The data of the study were gathered through the following instruments: observation checklists, field notes, and test. The data were analyzed to obtain the findings of the research. The findings showed that the appropriate ways used in implementing series picture consisted of the following steps: (1) leading students to the material to be done with familiar and interesting picture, (2) giving examples of essays with interesting series pictures, (3) explanation of writing techniques with interesting series pictures, (4) explanation of the elements of writing simple essays, (5) Making an essay with the interesting and familiar series pictures (6) Repairing the teacher's correction results, (7) Asking students to give questions.
Aislamiento y elucidación estructural por resonancia magnética nuclear (RMN 1H, RMN 13C, DEPT135, COSY y HSQC) del compuesto (E)-1,3,5-trimetoxi-2-(prop-1-enil) benceno extraído de hojas de Piper patulum.
Authors: Castillo-Arroyave José , Fuentes Byron , López-Mayorga Byron , Álvarez-Toledano Cecilio 
Published: October 2022

Guatemala es un país de gran diversidad biológica, la que ha permitido a diferentes investigadores de productos naturales, obtener resultados de interés y relevancia científica, principalmente sobre propiedades farmacológicas, sin embargo, hasta el momento se desconoce la estructura molecular, conformaciones y configuraciones exactas de muchos de los metabolitos secundarios responsables de dichas propiedades. Por lo tanto, en esta investigación se planteó como objetivo aislar y elucidar la estructura de un fenilpropanoide obtenido en las hojas de Piper patulum. El aislamiento se realizó por extracciones líquido-líquido y técnicas cromatográficas (cromatografía en columna -CC-), obteniendo .092 g del compuesto de interés. La elucidación se realizó por espectroscopía de masas, espectroscopia infrarroja -IR- y experimentos de resonancia magnética nuclear -RMN-, dando como resultado la estructura correspondiente a (E)-1,3,5-trimetoxi-2-(prop-1-enil) benceno. Posteriormente el fenilpropanoide presentó actividad antioxidante mediante la prueba cualitativa con 2,2-difenil-1-picrilhidrazilo -DPPH-.
Pentingnya Doa bagi setiap Orang Kristen Berdasarkan ST. Aphrahat
Authors: Zebua Boyman Aspirasi 
Published: October 2022

This article discusses the nature and meaning of prayer offered by St. Aphrahat. The meaning that will be carried out by humans often does not have a meeting point between human desires and God's will. Humans actually interpret prayer as a tool that is only used for a short time with a short desire as well. This means that prayer can be carried out according to when humans want to pray and what is the situation of the human being who is praying at that time. On the other hand St. Aphrahat looks at prayer from a more spiritual perspective. Aphrahat considers that a prayer must be based on how the human experiences the knowledge of the person of God so that they can understand how God's will can be expressed in human life. So this study aims to discuss the importance of prayer for everyone who is not based on St. Aphrahat. The research method used in writing this article is the library method. The results of this study explain that prayer plays an important role in making the journey and journey of human life so that these people get safe and prosperous in God. St. Aphrahat said when humans pray, the prayer that is said must come from a pure heart and offer it completely to God. praying like this is praying according to God will. Artikel ini membahas bagaimana hakikat dan pemaknaan doa yang ditawarkan oleh St. Aphrahat. Pemaknaan akan doa oleh manusia seringkali tidak memiliki titik temu antara keinginan manusia dan kehendak Allah. Manusia justru memaknai doa sebagai alat yang hanya digunakan dalam waktu singkat dengan keinginan yang singkat pula. Artinya doa dapat terlaksana sesuai dengan kapan manusia tersebut ingin berdoa dan bagaimana situasi manusia tersebut yang mengharuskan dia memanjatkan doa pada saat itu. Di lain sisi St. Aphrahat melihat doa dari sudut spiritual secara lebih mendalam. Aphrahat menilai bahwa sebuah doa harus berdasarkan bagaimana manusia tersebut mengalami pengenalan akan pribadi Allah sehingga dapat mengerti bagaimana kehendak Allah dapat dinyatakan dalam kehidupan manusia tersebut. Sehingga penelitian ini bertujuan membahas tentang pentingnya doa bagi setiap orang Kristen yang didasari dari St. Aphrahat. Metode penelitian yang digunakan dalam menulis artikel ini adalah metode literatur. Hasil penelitian ini memperlihatkan bahwa doa memegang peranan penting untuk kelangsungan dan perjalanan hidup manusia agar orang tersebut memperoleh selamat dan sejahtera di dalam Tuhan. St. Aphrahat mengatakan ketika manusia berdoa, doa yang dipanjatkan itu mesti berasal dari hati yang murni dan dipersembahkan sepenuhnya bagi Tuhan. Berdoa seperti ini yang dinamakan berdoa sesuai dengan kehendak Allah. Kata kunci: Doa; St. Aphrahat; Manusia; Allah; Berdoa.
Gambaran Pengetahuan Perawat dalam Penerapan ABCDEF Bundle di Intensive Care Unit (Icu)
Authors: Mutajir Mohamat , Widyaningtyas Ns. Nur Hafizhah 
Published: October 2022

Latar Belakang : ABCDEF Bundle (A, Assess, prevent and manage pain; B, Both Spontaneous Awakening and Spontaneous Breathing Trials [SATs/SBTs]; C, Choise of Analgesia and Sedation; D, Delirium, Assess, Prevent and Manage; E, Early mobility and exercise; and F, Family engagement and empowerment) adalah sebuah panduan pemantauan pasien di ICU. Panduan ini digunakan untuk mengintegrasikan pengkajian, pencegahan dan penanganan nyeri, agitasi dan delirium, memfasilitasi program weaning ventilator, program mobilisasi dini dan latihan, dan melibatkan serta memberdayakan anggota keluarga dalam perawatan pasien di Intensive Care Unit (ICU).
Tujuan : Tujuan penelitian ini adalah menjelaskan gambaran pengetahuan perawat dalam penerapan ABCDEF Bundle di ICU.
Metode : Desain penelitian ini adalah deskriptif survei dengan pendekatan cross-sectional. Kuesioner ABCDEF Bundle berisi 38 item pertanyaan, telah melewati tahap uji validitas dan reliabilitas dengan hasil 0,950.
Hasil : Hasil penelitian menunjukkan pengetahuan perawat dalam penerapan ABCDEF Bundle 9,8% memiliki pengetahuan baik, 18% cukup baik dan 72,2% memiliki pengetahuan kurang baik. Pengetahuan tertinggi 45,9% pada elemen A, 42,6% pada elemen E, 24,6% pada elemen B, 11,5% pada elemen C, 9,8% pada elemen F, dan 6,6% pada elemen D. Kesimpulan: Sebagian besar perawat memiliki pengetahuan yang rendah, dikarenakan belum adanya informasi dan kebijakan penerapan ABCDEF Bundle di ICU.
Kesimpulan : Diperlukan peningkatan pengetahuan tentang ABCDEF Bundle, maka perawat perlu mengikuti seminar/workshop, kebijakan penerapan bundle dalam bentuk SOP, penambahan materi pada pelatihan ICU dasar dan kurikulum pendidikan, serta penyediaan sarana penunjang di Rumah Sakit.