bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Kusama Retrospective and the Future of The Tel Aviv Museum of Art
Authors: Katz Maya Balakirsky 
Published: October 2022

Abstract
Following two years of heavy COVID restrictions, the Tel Aviv Museum of Art opened the “first-ever retrospective in Israel” of the Japanese artist Yayoi Kusama. Beyond the pioneering artist that is the subject of the retrospective and what it says about the Israeli public that is drawn to her work, the exhibition also invites analysis into the restaging of art exhibitions originating in another country, in this case a German museum, with all the implications that such a venture raises in Israel. In breaking down the curatorial modus operandi of restaging a borrowed exhibition designed by the Gropius Bau Museum in Berlin in Tel Aviv, this paper explores the museological craft of restaging exhibitions. In its original conception, the Gropius Bau focused on Kusama’s art “from a European and particularly from a German perspective,” highlighting Kusama’s “influence” on the European art scene during the time she spent in Germany in the late 1960s. The Tel Aviv Museum made significant changes to this scholarly conceptual core, perhaps sensitive to any claim that positioned Berlin as a cosmopolitan city after the Holocaust, by opting for an “affective” visitor experience. The site-specific textuality of this endeavor foregrounds the Tel Aviv Museum’s performance of itself in its twin roles in the nation’s history and its internationalization of the country’s cultural capital. I suggest that the Kusama exhibition reflects a new direction for the broader practices of art curatorship in the oldest art museum in the country.
Risankizumab-rzaa: A New Therapeutic Option for the Treatment of Crohn’s Disease
Authors: Choi David , Sheridan Hilary , Bhat Shubha 
Published: October 2022

Objective: To review the pharmacologic and clinical profile of risankizumab-rzaa in the treatment of Crohn’s disease (CD). Data Sources: A PubMed search was performed from inception to August 2022 using keywords risankizumab, risankizumab-rzaa, interleukin-23 inhibitor, and Crohn’s disease. Information was obtained from package inserts as well as published abstracts. Study Selection and Data Extraction: Phase 2 and 3 studies plus relevant literature on risankizumab-rzaa pharmacologic and clinical profile were reviewed. Data Synthesis: Risankizumab-rzaa approval was based on ADVANCE, MOTIVATE, and FORTIFY. In these 3 phase 3 studies involving patients with moderate to severe CD, risankizumab-rzaa, when compared with placebo, resulted in clinical remission and endoscopic response in a significantly higher proportion of patients in both the induction and maintenance phase. In addition, risankizumab-rzaa met the secondary endpoints of clinical response, endoscopic improvement, corticosteroid-free remission, and mucosal healing. Common adverse events noted include nasopharyngitis, arthralgia, headache, abdominal pain, and nausea. Relevance to Patient Care and Clinical Practice: Risankizumab-rzaa is the first selective IL-23 inhibitor approved for CD and provides an additional therapeutic option for patients, particularly those who have been previously treated with other advanced inflammatory bowel disease therapies. Additional studies are required to determine how to best position risankizumab-rzaa in both bio-naïve and bio-experienced patients with CD. Conclusions: Risankizumab-rzaa is the most recent therapeutic advance for CD. It has a selective mechanism of action with a similar safety profile comparable with other currently approved advanced therapies.
Emotion in multivarietal family language policy in Flanders
Authors: Naborn Lars , Van De Mieroop Dorien , Zenner Eline 
Published: October 2022

Aims: This study on Belgian Dutch caregivers aims to complement research on multilingual family language planning with a multivarietal perspective. As transitions between varieties are often more gradual, it is revealing to study which emotions surface in caregivers’ reflection on these varieties. The Belgian Dutch case is selected given its historically highly emotional macro-level language debate, its exoglossic norm and its transition from diglossia to diaglossia. Methodology: The aim is pursued through mixed methodology, combining variationist analysis with a bottom-up discourse analytic approach. Data and analysis: We juxtapose data from two Belgian Dutch families. For each family, a qualitative analysis identifies the expressions of (the lack of) emotions found in metalinguistic interviews on varieties of Dutch with the caregivers (80’). This information is triangulated with a quantitative analysis of the caregivers’ use of standard and nonstandard pronouns of address in self-recorded dinner table conversations (260’; N = 1004). Findings: Results reveal caregivers’ attempts to manage conflicting emotions related to the Flemish language situation, and how they lead to (dis)harmony in the family. Originality: This paper contributes to our understanding of emotions in family language policy (FLP) in its focus on a multivarietal context and in its mixed methodology. Implications: Our findings resonate with research on multilingual FLP’s, which we tie to caregivers’ diglossic description of the diaglossic Flemish context. The shifting relationship between emotions expressed in the interviews and the language choices made in practice, overall support the value of mixed methods FLP research.
The prevalence of intimate partner violence among Iranian pregnant women: a systematic review and meta-analysis
Authors: Raziani Yosra , Hasheminasab Leila , Gheshlagh Reza Ghanei , Dalvand Pegah , Baghi Vajiheh , Aslani Marzieh 
Published: October 2022

Background: Intimate partner violence against pregnant women is an important public health concern and human rights issue. According to the various findings of previous studies, this study was conducted to assess the pooled prevalence of intimate partner violence against Iranian women. Methods: In this systematic review and meta-analysis, a literature search was conducted in databases such as PubMed, Scopus, Web of Science, MagIran, and Scientific Information Database without a time limit. Heterogeneity was assessed by Cochrane Q test statistics and the I2 test, and the results were incorporated into a random effects model to estimate the prevalence of intimate partner violence. Data analysis was performed using R software version 4.3.2. Results: The overall prevalence of intimate partner violence was reported to be 51.5% (95% confidence interval (CI) 45.0–58.1), and the prevalence rate of physical, sexual, and psychological intimate partner violence was 18.0% (95% CI 15.1–20.9), 22.1% (95% CI 17.7–26.60) and 43.2% (95% CI 36.6–49.8), respectively. The lowest level of physical, sexual, and emotional intimate partner violence rate was observed in district 1 of Iran (includes Tehran, the capital of Iran and the surrounding provinces). The rate of physical and sexual intimate partner violence prevalence decreased with the increased mean age of the husband ( P=0.005) and the mean age of the wife ( P=0.035), respectively. Conclusions: Studies included in this review report that more than half of Iranian women experience violence during pregnancy. In order to prevent adverse maternal and neonatal consequences, it is necessary to identify these women and introduce them to support centres.
Percutaneous Puncture Embolization for Recurrent Pulmonary Arteriovenous Malformation After Failed Initial Treatment: A Case Report
Authors: Chen Lumin , Liu Yuyu , Chen Renbiao 
Published: October 2022

Background Transcatheter embolization is a commonly used minimally invasive technique in the treatment of pulmonary arteriovenous malformation (PAVM) with a high probability of post-operative recurrence, and some recurrent cases of PAVM cannot be treated via pulmonary arterial re-embolization. Here, we report the first case, to our knowledge, a 55-year-old female undergoing percutaneous direct puncture embolization for recurrent PAVM with good short-term efficacy. Case Presentation The patient was a 55-year-old female presenting to the emergency department of our hospital with acute exacerbation of chest tightness and shortness of breath for 2 hours. The patient was diagnosed with PAVM and undergone embolization half a year ago. DSA-guided embolization was performed through percutaneous puncture approach. After embolization with four spring coils, the blood flow to the PAVMs was stopped and the surgery completed. The patient reported improvement of chest tightness and shortness of breath and was discharged from the hospital 3 days later. Conclusion Our case was unique as a portion of the PAVMs was closely attached to the chest wall and PVP was slightly increased, which made percutaneous puncture embolization possible. Our case can be helpful in the treatment of recurrent PAVM in patients who cannot undergo re-embolization through pulmonary artery.
Midfoot Joint Arthrodesis Using Compression Plate With Lag Screw Augmenting With Highly Porous β-Tricalcium Phosphate and Bone Marrow Aspirate Concentrate
Authors: Lee Wonyong , MacDonald Justin , Prat Dan , Chao Wen , Farber Daniel C. , Wapner Keith L. 
Published: October 2022

Background There is still a controversy regarding the most optimal fixation instruments and bone graft materials for midfoot joint arthrodesis. We present the results of midfoot joint arthrodesis using compression plate with lag screw augmenting with highly porous β-tricalcium phosphate (β-TCP) and bone marrow aspirate concentrate (BMAC). Methods We performed a retrospective review of patients undergoing midfoot joint arthrodesis using compression plate with lag screw augmenting with highly porous β-TCP and BMAC from January 2014 to May 2019. The radiographic bony union rate was investigated. Postoperative complications and reoperations were also reviewed. A total of 36 patients (37 feet) including 75 joints were available in this study. Results A high union rate was achieved as of 97.3% in 73 of 75 joints. Nonunion occurred in 2 patients including 2 joints. Other than nonunion, there were no major complications such as deep infection. Minor complications (5 of 75 joints, 6.7%) included hardware irritations. Reoperations were required in 1 patient for revision of arthrodesis and symptomatic hardware removal was performed in all 5 hardware irritation cases. Conclusion Based on our results, the fixation construct of compression plate with lag screw augmenting with highly porous β-TCP and BMAC is safe and effective for midfoot joint arthrodesis with an excellent union rate and a low complication rate. Level of Evidence: IV, retrospective case series
Effect of Fibular Malrotation on Tibiotalar Joint Contact Mechanics in a Weber B Ankle Fracture Model
Authors: Ayala Alfonso E. , Khwaja Ansab , Goodison Brianna C. , Smith Simeon L. , Kim Samuel Y. , Irwin Jared T. , Latt L. Daniel 
Published: October 2022

Background In minimally displaced Weber B ankle fractures, the distal fibular fracture fragment can be externally rotated. This malrotation is difficult to detect on radiographs and, when left malreduced through nonoperative treatment, may contribute to altered joint mechanics, predisposing to posttraumatic osteoarthritis. This study evaluates the effects of fibular malrotation on tibiotalar joint contact mechanics. Methods Six cadaveric ankles were tested using a materials testing system (MTS) machine. A tibiotalar joint sensor recorded contact area and pressure. Samples were tested in the intact, neutrally rotated, and malrotated state. Each trial applied a 686N axial load and a 147N Achilles tendon load in neutral position, 15° dorsiflexion, and 15° plantarflexion. Results In the comparison of malrotated to intact ankles, peak contact pressure was found to be significantly greater at neutral flexion (intact 5.56 MPa ± 1.39, malrotated 7.21 MPa ± 1.07, P = .03), not significantly different in dorsiflexion, and significantly decreased in plantarflexion (intact 11.2 MPa ± 3.04, malrotated 9.01 MPa ± 1.84, P = .01). Significant differences in contact area were not found between conditions. Conclusion The findings suggest that fibular malrotation contributes to significant alterations in tibiotalar joint contact pressures, which may contribute to the development of posttraumatic osteoarthritis. When malrotation of the fibula is suspected on plain radiographs, a computer tomography (CT) scan should be obtained to evaluate its extent and further consideration should be given to surgical treatment. Levels of Evidence: Level V: Bench testing
Long-term impact of fluoroquinolone-sparing strategies for empirical treatment of acute uncomplicated cystitis among ambulatory patients
Authors: Kon Shelley , Meslovich Dina , Valdez Carolyn , Jenkins Timothy C. , Shihadeh Katherine , Franco-Paredes Carlos , Price Connie S. 
Published: October 2022

Background: Acute uncomplicated cystitis is common among outpatients and frequently leads to antibiotic prescriptions, making urinary tract infections (UTIs) an important area for antimicrobial stewardship initiatives. Infectious Disease Society of America (IDSA) guidelines promote alternative agents in place of fluoroquinolones for acute uncomplicated cystitis. Despite IDSA guidance, adherence to the guideline remains low in the United States (US). Several studies have described interventions to improve guideline-concordant prescribing for UTIs. However, the long-term sustainability and impact of fluoroquinolone (FLQ)-sparing strategies on community antimicrobial resistance and treatment outcomes are unknown. The objectives of this study were to characterize current antibiotic prescribing patterns, treatment failures and Escherichia coli resistance rates in a setting which instituted FLQ sparing strategies for UTIs in 2007. Methods: Retrospective cohort study of women aged ⩾ 18 diagnosed with acute uncomplicated cystitis based on International Classification of Diseases, 10th Revision (ICD-10) codes were included. Data were abstracted for ambulatory visits over a 6-month period, January 2018 to June 2018, at a large urban health care system. Treatment decisions were made by individual providers, and data were analyzed retrospectively. Nitrofurantoin (NFT) resistance was obtained from the institutional antibiogram and patient-level data. Treatment failure was defined as the need for a different antibiotic for UTI within 28 days of the original prescription. Results: NFT was the most frequently prescribed antibiotic ( n = 386, 71.6%) of empiric antibiotic prescriptions for UTIs. FLQs comprised 4.6% of all antibiotic prescriptions ( n = 25). Treatment failure rate was 2.3% in patients treated with NFT. Urine culture was ordered for only 26.8% of patients. Among the small group of patients with cultures ordered, E. coli remained 98.5% susceptible to NFT. Conclusions: This study is the first to report significantly low rates (4.6%) of FLQ prescribing for acute uncomplicated cystitis. Treatment failure rate was low with empiric NFT. Increased NFT resistance among E. coli was not observed at the institution or among the subset of patients with E. coli positive urine cultures. These findings support current IDSA treatment guidance for uncomplicated cystitis.
Real-world experience with 240 mg of galcanezumab for the preventive treatment of cluster headache
Authors: Mo Heejung , Kim Byung-Kun , Moon Heui-Soo , Cho Soo-Jin 
Published: October 2022

Abstract
Background
Galcanezumab of 300 mg monthly is the FDA approved preventive medication for cluster headache (CH) during the cluster period. Compared to the 120 mg galcanezumab syringe for the treatment of migraines, the 100 mg syringe for CH has globally not been as widely available. The aim of our study was to investigate the preventive efficacy and tolerability of two 120 mg galcanezumab doses for episodic CH in clinical practices.

Methods
We evaluated patients with CH who received at least 1 dose of 240 mg (2 prefilled syringe of 120 mg) of galcanezumab in the 3 university hospitals from February 2020 to September 2021. In the patients with episodic CH, the efficacy and safety data of galcanezumab were analyzed regarding to the presence of the conventional preventive therapy at the timing of therapy of galcanezumab. The data of other subtypes of CH were separately described.

Results
In 47 patients with episodic CH, galcanezumab was started median 18 days after the onset of current bout (range 1–62 days) and 4 patients (10.8%) received second dose of galcanezumab. The median time to the first occurrence of 100% reduction from baseline in CH attacks per week after galcanezumab therapy was 17 days (25% to 75% quartile range: 5.0 ~ 29.5) in all patients with episodic CH, 15.5 days (3.8 ~ 22.1) in 36 patients with galcanezumab therapy add-on conventional preventive therapy, 21.0 days (12.0 ~ 31.5) in 11 patients started galcanezumab as initial preventive therapy. Among 33 patients with headache diary, the proportion of patients with 50% or more reduction in weekly CH attacks at week 3 from baseline were 78.8%. There was no significant difference in the proportion of patients with a reduction of at least 50% in weekly frequency of CH attacks at week 3 between 24 patients received galcanezumab therapy add-on conventional preventive therapy and 9 patient who received initial galcanezumab therapy. (83.3%, vs 66.7%, p = 0.36). There were no significant differences in proportion of “very much better or “much better” between 36 patients received galcanezumab therapy add-on conventional preventive therapy and 11 patient who received initial GT (86.1%, vs 63.6%, p = 0.18).

Conclusion
One 240 mg dose of galcanezumab with/without conventional therapy for the prevention of CH is considered effective and safe in clinical practices, as seen in the clinical trial of galcanezumab.
OsWHY1 Interacts with OsTRX z and is Essential for Early Chloroplast Development in Rice
Authors: Qiu Zhennan , Chen Dongdong , Teng Linhong , Guan Peiyan , Yu Guoping , Zhang Peiliang , Song Jian , Zeng Qiangcheng , Zhu Li 
Published: October 2022

AbstractWHIRLY (WHY) family proteins, a small family of single-stranded DNA (ssDNA) binding proteins, are widely found in plants and have multiple functions to regulate plant growth and development. However, WHY in rice has received less attention. In this study, we continued our previous study on OsTRX z that is important for chloroplast development. OsTRX z was discovered to interact with OsWHY1, which was confirmed using yeast two-hybrid, pull-down, and BiFC assays. Subsequently, the oswhy1 mutants were obtained by CRISPR/Cas9, which exhibited an albino phenotype and died after the three-leaf stage. Consistent with this albino phenotype, low amounts of Chl a, Chl b, and Car were detected in the oswhy1-1 mutant. Moreover, the oswhy1-1 mutant had chloroplasts with disrupted architecture and no stacked grana and thylakoid membranes. Subcellular localization showed that the OsWHY1-GFP fusion protein was targeted to the chloroplast. What’s more, OsWHY1 was found to be preferentially expressed in young leaves and was involved in chloroplast RNA editing and splicing. Mutation of OsWHY1 significantly affected the expression of chloroplast and ribosome development-related and chlorophyll synthesis-related genes. In conclusion, OsWHY1 contributes to early chloroplast development and normal seedling survival in rice. These results will further elucidate the molecular mechanism of chloroplast development and expand our understanding of WHY1 functions.
Serous cystadenocarcinoma of the testis: case report of a rare entity
Authors: Fadli Mohammed El , Benhima Nada , Essâdi Ismail , Belbaraka Rhizlane 
Published: October 2022

Abstract
Background
Germ cell tumors account for more than 95% of testicular cancers followed by sex-cord stromal tumors. The occurrence of serous cystadenocarcinoma in testicular and paratesticular tissue is very rare with distinct clinical behavior.

Case presentation
Herein, we report the case of a 39-year-old man who presented with right testicular swelling. Anatomopathological examination of the right orchiectomy revealed a high-grade paratesticular serous cystadenocarcinoma. Long-term follow-up with close monitoring was adopted in the absence of concomitant metastasis. The patient was disease-free at two years post-surgery.

Conclusion
Owing to its scarcity, there are no standardized guidelines for optimal management of this histological entity. Sharing case reports provide valuable information to support clinical decisions.
Prevalence of co-infection and genetic diversity of avian haemosporidian parasites in two rehabilitation facilities in Iran: implications for the conservation of captive raptors
Authors: Nourani Leila , Aliabadian Mansour , Mirshamsi Omid , Dinparast Djadid Navid 
Published: October 2022

Abstract
Background
Various haemosporidian parasites infect raptors, especially captive hosts who may be more exposed. Diagnosis of threatening factors such as infectious diseases indirectly has a significant role in protecting endangered or threatened species that may boost the mortality or extinction resulting from declined reproduction. Few investigations have been performed in captive hosts to detect the prevalence of haemosporidian parasites and define genetic diversity in west Asia. For the first time, the current study was designed to determine the prevalence and genetic diversity of haemosporidian parasites in captive raptors by molecular methods in two rehabilitation facilities in North and North-east Iran and to define phylogenetic relationships of detected lineages circulating in raptors.

Results
Molecular characterization of the haemosporidian parasite was accomplished by PCR-based method and DNA sequencing in 62 captive raptors. The overall prevalence was ~ 36% with higher infection of Haemoproteus spp. than Leucocytozoon spp. Plasmodium infection was not detected in any host. Results showed that 22 individuals (of 10 species) were infected with unique lineages. Genus Haemoproteus was detected in 26.66% of examined individuals (of eight species) and Leucocytozoon was found in 10% of individuals (of four species). The molecular analysis could detect ten lineages (nine Haemoproteus spp. and one Leucocytozoon spp.) which were categorizes as new and six lineages which have been previously detected in the other investigations.

Conclusions
The Bayesian phylogenetic analysis derived from obtained data in the present study and published lineages in previous investigations indicated the probable host specificity of Haemoproteus and Leucocytozoon parasites in several sub-clades at hosts’ order and genus level. As monitoring the parasite loads of captive birds when admitted reduce the risk of infecting hosts in captivity at those locations, we designed this study to determine infection prevalence and genetic diversity of blood parasites in raptors examined in Iran. These results allow mapping of haemosporidian distribution and shed light on the depth of their diversity in Iran to protect species by identification of risk in rehabilitation facilities.