bluuebunny/crossref_metadata_2025_split huggingface dataset:
Extraction of Frozen Berry Raw Materials with a Vibration Tray Device
Authors: Plotnikova Liubov , Plotnikov Igor , Ivanov Pavel , Semenov Andrey , Plotnikova Irina , Plotnikov Konstantin 
Published: January 2022

Introduction. Products containing natural extracts are in great demand. However, poor production technologies make them too expensive to satisfy consumer demand. As a result, a variety of intensification methods have been developed to increase the economic efficiency of extraction, e.g. low-frequency mechanical vibrations. However, frozen raw materials have to be processed at low temperatures, which makes the method less efficient. The research objective was to intensify the extraction process from frozen berries in a vibration tray device by increasing the temperature of the system of interacting phases.
Study objects and methods. The research involved frozen cranberries and blueberries. They grow everywhere in Western Siberia and are rich vitamins and minerals. The berries were subjected to slow freezing at –18°C, which destroyed the cell structure and increased the processing efficiency. The study was carried out in a lab device with a vibrating tray. All parameters were measured by standard methods.
Results and discussion. The extraction device was equipped with a jacket into which a coolant was fed, i.e. water with a temperature of 55°C. A preliminary series of experiments revealed two negative aspects associated with the supply of coolant into the jacket. First, the surface layer started to thaw, which reduced the efficiency of grinding. Second, the processing time increased. A new method was developed to solve these problems: the coolant was supplied at the end of the grinding. The time of the coolant supply depended on the type of raw materials. The processes that occurred within the device depended on two factors: the frequency of vibrations of the tray and the diameter of the holes in the tray. These factors could be adjusted to intensify the process, but they increased the power costs and energy consumption. A series of experiments determined the optimal values of these parameters. A mathematical analysis revealed regression equations, i.e. how the destruction time and power costs affected the main parameters. The established optimal process parameters made it possible to determine the minimal time of the destruction process: for cranberries – 2.5 min, for blueberries – 1.5 min. The minimal power consumption was 17.8 watts for cranberries and 11.7 watts for blueberries.
Conclusion. The research increased the economic efficiency of the technological process of natural extraction, which can reduce the cost of the finished product and increase its availability. The values of the process parameters can be used to design new similar devices and serve as practical recommendations for berry extraction in vibration tray devices.
Developing New Software for Functional Food Production
Authors: Titorenko Elena , Trofimova Natalia , Ermolaeva Evgenia , Trofimov Ivan , Breskin Leonid , Surkov Igor , Astakhova Natalia 
Published: January 2022

Introduction. Statistical methods of data processing and IT technologies make it possible to introduce new modern methods of hazard and risk analysis in food industry. The research objective was to develop new software that would link together various risk-related production data.
Study objects and methods. The research featured food production company LLC Yug (Biysk, Russia) that specializes in functional products and various ready-made software automation solutions. The study also involved statistical methods, methods of observation, collection of primary information, sequential top-down development of algorithms, and the Java programming language.
Results and discussion. Food producers have a registration procedure for inconsistencies and violations of permissible limits at critical control points. The authors developed a new software program that allows production line operators to enter data on downtime and other violations of the production process. The program makes it possible for managers to receive up-to-date reports on various criteria, identify violations, and select appropriate corrective actions. This ready-made solution automates the process of accounting and hazard analysis. The program was tested at LLC Yug with the focus on the time that operators and managers needed to register the problem, analyze the data, develop corrective or preventive measures, and apply them.
Conclusion. The new software proved to be less time-consuming than standard procedures applied in food industry and made it possible to save the time that operators and managers spent on decision making and reporting.
Hydrological modeling for streamflow and sediment yield simulation using the SWAT model in a forest-dominated watershed of north-eastern Himalayas of Kashmir Valley, India
Authors: Gull Sarvat , Shah Shagoofta Rasool 
Published: January 2022

Abstract
In this study, the Soil and Water Assessment Tool (SWAT) model was used to examine the spatial variability of sediment yield, quantify runoff, and soil loss at the sub-basin level and prioritize sub-basins in the Sindh watershed due to its computational efficiency in complex watersheds. The Sequential Uncertainty Fitting-2 approach was used to determine the sensitivity and uncertainty of model parameters. The parameter sensitivity analysis showed that Soil Conservation Services Curve Number II is the most sensitive model parameter for streamflow simulation, whereas linear parameters for sediment re-entrainment is the most significant parameter for sediment yield simulation. This study used daily runoff and sediment event data from 2003 to 2013; data from 2003 to 2008 were utilized for calibration and data from 2009 to 2013 were used for validation. In general, the model performance statistics showed good agreement between observed and simulated values of streamflow and sediment yield for both calibration and validation periods. The noticed insights of this research show the ability of the SWAT model in simulating the hydrology of the Sindh watershed and its reliability to be utilized as a decision-making tool by decision-makers and researchers to influence strategies in the management of watershed processes.
Livelihood functions of fisher households under cold-water production environment of Kashmir, Jammu and Kashmir, India
Authors: Baba S. H. , Asimi Oyas , Bhat Ishrat F. , Khan Irfan A. 
Published: January 2022

Abstract
This study comprehensively investigated the livelihood security scenario of fisher households employing the CARE framework with little modifications, in Kashmir, India. Primary data for this study was collected from selected fisher households, and a regression function was fitted to quantify the determinants of livelihood security. The findings revealed that fishing has been their dominant livelihood option. The landholding owned by the households was meagre enough to carry out farming or domesticate animals on commercial lines. Poor capital endowments place them at less livelihood security level; however, the respondents with diversified income have a relatively higher index value for livelihood. The regression estimates indicated that barring social and natural capital, all forms of capital have a significant role to play in securing their livelihood. Poor livelihood security, coupled with less income flow, has made their survival vulnerable to various distresses and health disorders, including the prevalence of infant and maternal mortality. Their dietary intake was undesirably less than their dietary recommendations. The COVID-19 pandemic was perceived as a shock to their livelihood security. Further, public investment, which is pertinent for the growth of the fisheries sector, has shown a discouraging trend. The study concluded with a few policy suggestions for securing the livelihood of the fisher community.
Synthesis and Studies of Anticancer and Antimicrobial Activity of New
Phenylurenyl Chalcone Derivatives
Authors: Akdeniz Güneş Y. , Akgün Hülya , Özakpınar Özlem B. , Duracık Merve , Öztürk Mehmet , İşcan Evin , Başoğlu Faika 
Published: January 2022

Background:
Phenylurenyl chalcone structures have the potential to act as a scaffold in anticancer drug discovery.

Methods:
N-Phenethyl-N'-{4-[(2E)-3-phenylprop-2-enoyl]phenyl}urea, 4/3-[(2E)-3-substitutedphenylprop-2-enoyl]phenyl}-N-phenylurea,4/3-[(2E)-3-substitutedphenyl
prop-2-enoyl]phenyl}-N-methylphenyl urea and {4/3-[(2E)-3-substitutedphenylprop-2-enoyl]phenyl}-N-ethylphenyl urea derivatives(1-35)were prepared and evaluated for their anticancer and antimicrobial activity against A-549 Hep-3B, HT-29, CF-7, PC-3, K-562 NIH-3T3 and Huh-7 cell lines and against Staphylococcus aureus (ATCC 6538), Pseudomonas aeruginosa (ATCC 9027), Escherichia coli (ATCC 8739) and Candida albicans (ATCC 10231), respectively.

Results:
While compounds 2, 26, 29, and 34 showed moderate cytotoxic activity on cell line Huh 7, compounds 14 (IC50: 6.42 µM), 16 (IC50: 5.64 µM), 19 (IC50: 6.95 µM) and 34 (IC50: 6.87 µM) showed good cytotoxic activity on Huh-7 cell line close to Sorafenib (IC50: 4.29 µM) (as reference). MIC values of compounds 4 and 22 against E. coli were 25 μg/ml, of compounds 3, 14 and 29 against P. aeruginosa 25 μg/ml and of compounds 11 and 33 against S. aureus 25 μg/ml. On the other hand, the minimum inhibitory concentration of all tested compounds against C. albicans was 25 μg/ml.

Conclusion:
N-Phenethyl-N'-{4-[(2E)-3-phenylprop-2-enoyl]phenyl}urea may be a new candidate to be developed as an anticancer compound.
Synthesis of New Pyrazole Hybrids as Potential Anticancer Agents with Xanthine
Oxidase Inhibitory Activity
Authors: Hassan Mohd. Zaheen , Alsayari Abdulrhman , Asiri Yahya I. , Bin Muhsinah Abdullatif 
Published: January 2022

Aims:
The study aims to synthesize hybrid molecules containing pyrazole and aryldiazenyl/arylhydrazono
fragments with promising anticancer activity.

Background:
The clinical effectiveness of anticancer drugs is limited by their adverse side effects and patient resistance.
Therefore, the development of safer classes of drugs through rational drug design is imperative.

Objective:
Considering the anticancer potential of the pyrazole moiety, the study was carried out with the objective of
synthesizing some hybrid pyrazole derivatives with anticancer potential.

Method:
The anticancer potential of these pyrazolyl analogues were evaluated by sulforhodamine B assay using three
cancer cell lines MCF-7, HepG2, and HCT-116.

Result:
HCT-116 was the most sensitive cell line against these pyrazolyl analogues. Among these newly synthesised
derivatives, 1-(4-((4-bromophenyl)diazenyl)-3,5-dimethyl-1H-pyrazol-1-yl)-2-(naphthalen-2-yloxy)ethan-1-one (5e)
emerged as a promising anticancer agent (IC50 3.6-24.6 μM), having a xanthine oxidase inhibitory effect (IC50 10.87
μM). To obtain further insights into the binding interactions of these molecules, molecular docking studies were also
carried out.

Conclusion:
In summary, our findings suggest that these hybrid pyrazolyl derivatives can be considered as potential
lead molecules for anticancer agents.
Natural Immunity Boosters as Therapeutic Interventions in the Era of the
COVID-19 Pandemic
Authors: Noureen Sibgha , Rehman Kanwal , Hamid Akash Muhammad Sajid 
Published: January 2022

Abstrack:
COVID-19, a pandemic caused by SARS-CoV-2, has been spread all over the world and is responsible for serious fatalities. SARS-CoV-2 belongs to the family of β-coronavirus that affects pulmonary gas exchange and triggers cytokines storm. Vigorous inflammation, hyper-coagulation, a decrease in the lymphocytic count, and an increase in the neutrophilic count are observed in the second week after the onset of the disease. Fever, dry cough, sneezing, shortness of breath, and respiratory distress are the symptoms of COVID-19. The use of sanitizers, social distancing, vaccination, wearing gloves and face masks, and other preventative measures are all important in preventing coronavirus outbreaks. People with weak immunity are more susceptible to coronavirus. Various natural immunity boosters are known for their immune boosting properties; among them are vitamin C, D, and B complex, medicinal mushrooms, plant-based stuff, and minerals play important roles by increasing the beneficial flora of the human body. All these natural immunity boosters improve the innate and adaptive immune response against coronavirus. Hence, we conclude that the use of natural immunity boosters prevents the attack of coronavirus and makes a person stronger against the suspected attack of COVID-19 and/or other viral diseases.
Use of Health Information Technology by Adults With Diabetes in the United States: Cross-sectional Analysis of National Health Interview Survey Data (2016-2018)
Authors: Wang Seamus Y , Yeh Hsin-Chieh , Stein Arielle Apfel , Miller Edgar R 
Published: January 2022

Background
The use of health information technology (HIT) has been proposed to improve disease management in patients with type 2 diabetes mellitus.

Objective
This study aims to report the prevalence of HIT use in adults with diabetes in the United States and examine the factors associated with HIT use.

Methods
We analyzed data from 7999 adults who self-reported a diabetes diagnosis as collected by the National Health Interview Survey (2016-2018). All analyses were weighted to account for the complex survey design.

Results
Overall, 41.2% of adults with diabetes reported looking up health information on the web, and 22.8% used eHealth services (defined as filled a prescription on the web, scheduled an appointment with a health care provider on the web, or communicated with a health care provider via email). In multivariable models, patients who were female (vs male: prevalence ratio [PR] 1.16, 95% CI 1.10-1.24), had higher education (above college vs less than high school: PR 3.61, 95% CI 3.01-4.33), had higher income (high income vs poor: PR 1.40, 95% CI 1.23-1.59), or had obesity (vs normal weight: PR 1.11, 95% CI 1.01-1.22) were more likely to search for health information on the web. Similar associations were observed among age, race and ethnicity, education, income, and the use of eHealth services. Patients on insulin were more likely to use eHealth services (on insulin vs no medication: PR 1.21, 95% CI 1.04-1.41).

Conclusions
Among adults with diabetes, HIT use was lower in those who were older, were members of racial minority groups, had less formal education, or had lower household income. Health education interventions promoted through HIT should account for sociodemographic factors.
Using Natural Language Processing to Explore Mental Health Insights From UK Tweets During the COVID-19 Pandemic: Infodemiology Study
Authors: Marshall Christopher , Lanyi Kate , Green Rhiannon , Wilkins Georgina C , Pearson Fiona , Craig Dawn 
Published: January 2022

Background
There is need to consider the value of soft intelligence, leveraged using accessible natural language processing (NLP) tools, as a source of analyzed evidence to support public health research outputs and decision-making.

Objective
The aim of this study was to explore the value of soft intelligence analyzed using NLP. As a case study, we selected and used a commercially available NLP platform to identify, collect, and interrogate a large collection of UK tweets relating to mental health during the COVID-19 pandemic.

Methods
A search strategy comprised of a list of terms related to mental health, COVID-19, and lockdown restrictions was developed to prospectively collate relevant tweets via Twitter’s advanced search application programming interface over a 24-week period. We deployed a readily and commercially available NLP platform to explore tweet frequency and sentiment across the United Kingdom and identify key topics of discussion. A series of keyword filters were used to clean the initial data retrieved and also set up to track specific mental health problems. All collated tweets were anonymized.

Results
We identified and analyzed 286,902 tweets posted from UK user accounts from July 23, 2020 to January 6, 2021. The average sentiment score was 50%, suggesting overall neutral sentiment across all tweets over the study period. Major fluctuations in volume (between 12,622 and 51,340) and sentiment (between 25% and 49%) appeared to coincide with key changes to any local and/or national social distancing measures. Tweets around mental health were polarizing, discussed with both positive and negative sentiment. Key topics of consistent discussion over the study period included the impact of the pandemic on people’s mental health (both positively and negatively), fear and anxiety over lockdowns, and anger and mistrust toward the government.

Conclusions
Using an NLP platform, we were able to rapidly mine and analyze emerging health-related insights from UK tweets into how the pandemic may be impacting people’s mental health and well-being. This type of real-time analyzed evidence could act as a useful intelligence source that agencies, local leaders, and health care decision makers can potentially draw from, particularly during a health crisis.
Students' Perceptions in English Learning using 3 Online Media Applications as a Learning Media in Pandemic Period
Authors: Nurfitri Nurfitri 
Published: January 2022

Since the increase of Indonesian people exposed to Covid-19 was massively reported, our government has tried to find best solution to overcome this situation, one of them is conducting online learning for the students. At STIA Nusa, English learning which was originally done offline, was changed to online with the obligation to use several online media applications such as Zoom, Edmodo and Whatssap. The purpose of this study was to look at the students’ perception and ask the results of their English skills as well as offline learning. This research used qualitative, with data collection techniques are interviews with 128 students. The research results showed that 1). Zoom presents a new learning model even though most of them still say the lack of interaction, 2). The use of Edmodo for them is more interactive because they are able to repeat lessons and discuss with friends if there is a lack of understanding about learning and its user friendly features such as Facebook 3) the use of WhatsApp groups makes it easier for them to ask questions with the lecturer and through the voice note feature the lecturer can provide feedback what they need and through this application students can be rewarded so that it gives them the motivation to learn more during the pandemic.
Formation Conditions And Debris Flow Regime In Jiangjia Ravine, Yunnan, China – Applicability Of Russian Methodology
Authors: Ding Mingtao , Shnyparkov Aleksandr L. , Grebennikov Pavel B. , Khismatullin Timur I. , Sokratov Sergey A. 
Published: January 2022

The requirements of the debris flows’ parameters assessments vary from country to country. They are based on different theoretical and empirical constructions and are validated by data from different regions. This makes difficult comparison of the reported results on estimated debris flows activity and extent. The Russian normative documents for the debris flows’ parameters calculations are based on empirically-measured parameters in wide range of geological and climatic conditions at the territory of former USSR, but still not cover all the possible conditions of debris flow formation. An attempt was made to check applicability of the Russian empirical constructions for the conditions of the debris flows formation in Yunnan, China, where unique long-term dataset of debris flows characteristics is collected by the Dongchuan Debris Flow Observation and Research Station. The results show, that in general the accepted in Russia methodology of calculation of the parameters of debris flows of certain probability corresponded well to the observed in Dongchuan debris flows characteristics. Some discrepancies (in the average debris flow depth) can be explained by unknown exact return period of the actually observed debris flows. This allowed to conclude that the presently adopted empirical dependencies based on country-wide (USSR) empirical data can be extrapolated up to the monsoon climate and geological conditions of Yunnan province.
Utilisation du Média de la Chanson Populaire Française pour Ameliorer la Competence des Étudiants de Prononcer les Voyelles
Authors: Manik Rendep Delviana 
Published: January 2022

Cette recherche a pour but de savoir si l’utilisation du média de la chanson populaire française peut améliorer la compétence des étudiants de prononcer les voyelles en effectuant une recherche-action (PTK). L’objet de cette recherche est la classe Regulier B à la section française au deuxiéme semestre qui se compose de 15 étudiants. La recherche a été effectuée en deux cycles. Il a deux sortes des données recueillies au cours de la recherche, des données quantitatives et qualitatives. Les instruments de collecte des données quantitatives ont été prononcées les paroles, tandis que les données qualitatives sont recueillies par fiche d’observation. Basé sur l’analyses des données, la moyenne de la note des étudiants dans pré test est 49,8 en Cycle I 76,1 et au Cycle II 83,6. Basé sur la moyenne de note, on peut voir que la réalisation de prononcer les voyelles des étudiants en utilisant du média de la chanson populaire française montre une amélioration significative de 76,1 à 83,6. Donc, on peut conclure que la chanson populaire française peut ameliorér la compétence de prononcer les voyelles chez les étudiants de la section française au deuxiéme semestre.Mots Clés : Amélioration, Prononciation, Chanson Populaire.
STYLISTICS OF NEMOKKE IN JAVANESE WEDDING CEREMONY IN LANGKAT SUMATERA UTARA
Authors: SERVIYANA EVA , NATSIR MUHAMMAD , LUBIS SISILA FITRIANY 
Published: January 2022

The research was about Stylistics of Nemokke in Javanese wedding ceremony in Langkat Sumatera Utara. This study was conducted by applying descriptive qualitative design. The source of data was taken from the utterances of dukun manten and activities happened in Nemokke (traditional Javanese wedding ceremony) in Langkat Sumatera Utara. The data are the transcription of the Javanese ‘dukun manten’ utterances recording in Javanese wedding ceremony, especially in Nemokke and activities happened in Nemokke. The technique for analyzing the data is descriptive qualitative research based on Miles & Huberman (1984). The technique of collecting the data of this research is observation, recording and interview. The findings indicate that there were three Stylistics (Sympson, 2004) found in Javanese wedding ceremony, they were Semantics, Pragmatics and Discourse. It is suggested to the dukun manten in Javanese wedding ceremony to use Discourse to give information and to show the great meaning and audience understand.