bluuebunny/crossref_metadata_2025_split huggingface dataset:
A study on histopathological changes in ectopic tubal gestation
Authors: Rasheed Fathima , Vijayaraghavan Lilarani 
Published: June 2022

Background: Ectopic pregnancy is a serious cause of maternal morbidity and mortality. Fallopian tube is the most common site. Ectopic pregnancy is often the consequence of chronic salpingitis. The aim of the study was to identify the various histopathological changes in the fallopian tube, which are removed following an ectopic tubal gestation. The prevalence of various risk factors in ectopic tubal pregnancy was also investigated. Methods: This descriptive study included 160 cases of ectopic tubal gestation received in the department during the study period. Slides were studied for various changes like chronic salpingitis, acute salpingitis, salpingitis isthmica nodosa, endometriosis, tuberculosis etc. Patient’s clinical details were obtained from the medical records.Results: The most frequent pathological finding was chronic salpingitis followed by salpingitis isthmica nodosa. It was noted that all cases with a positive history of pelvic inflammatory disease (PID), showed evidence of chronic salpingitis during histopathological examination. Chronic salpingitis was also noted in 45% cases who did not give a history of PID. Among the risk factors, a history of tubal sterilization was the most frequent one.Conclusions: Even though the mortality has reduced, ectopic pregnancy causes significant morbidity and affects the fertility of women. The rise in incidence could be due to increase in prevalence of sexually transmitted diseases, increase in tubal sterilization practices and frequent use of assisted reproduction technology. It is evident from the study that many cases of PIDs are left unidentified.
The role of highly penetrant mutations in BRCA1 and CHEK2 genes in the pattern of associations of matrix metalloproteinase gene polymorphisms with breast cancer
Authors:   Belgorod State National Research University, Pavlova Nadezhda V. , Orlova Valentina S. ,   Belgorod State National Research University, Batlutskaya Irina V. ,   Belgorod State National Research University, Efremova Olga A. ,   Belgorod State National Research University, Ponomarenko Irina V. ,   Belgorod State National Research University
Published: June 2022

Актуальность: Рак молочной железы (РМЖ) это опухоль молочной железы злокачественного характера, которая занимает ведущее место как в структуре онкозаболеваний у женщин, так и среди причин смертности женского населения от злокачественных новообразований. Роль генетических факторов в формировании РМЖ не вызывает сомнений. Цель исследования:Изучить роль высокопенетрантных мутаций в генах BRCA1 и CHEK2 в характере ассоциаций полиморфизма генов матриксных металлопротеиназ (ММР) с РМЖ. Материалы и методы:Для решения поставленной цели исследования были сформированы следующие три выборки: 26 больных РМЖ, имеющие высокопенетрантные мутации в генах BRCA1 (c.5266dup (5382insC), c.68_69del (185delAG), 2080delA) и CHEK2 (I157T)), 332 больных РМЖ без герминальных мутаций в генах BRCA1 (c.5266dup (5382insC), c.68_69del (185delAG), 2080delA, 4153delA), BRCA2 (6174delT) и CHEK2 (I157T) и 746 женщин контрольной группы. В работе изучены десять полиморфизмов пяти генов матриксных металлопротеиназ (MMP1, MMP2, MMP3,MMP8 и MMP9). Анализ ассоциаций проводился методом логистической регрессии. Результаты:Генотип ТТ rs1940475 MMP8 у больных РМЖ, имеющих высокопенетрантные мутации в генах BRCA1 и CHEK2 (3,84%) встречается в 6-7 раз реже в сравнении как с пациентками, не имеющих этих мутаций (22,80% pperm=0,04), так и индивидуумами контрольной группы (26,18% ORcov=0,11 95%CIcov 0,01-0,81 pperm=0,03). Среди больных РМЖ, не имеющих высокопенетрантных мутаций в генах BRCA1 и CHEK2, с заболеванием ассоциирован полиморфизм гена ММР9: rs17576 (ORcov=0,81 pperm=0,03), rs2250889 (ORcov=0,61-0,66 pperm=0,03), rs3787268 (ORcov=2,03 pperm=0,04) и девять различных гаплотипов шести изученных локусов ММР9 (pperm<0,05). Заключение: Полиморфный локус rs1940475 MMP8 связан с риском развития РМЖ у женщин с высокопенетрантными мутациями в генах BRCA1 и CHEK2, а полиморфизм гена ММР9 ассоциирован с заболеванием у женщин, не имеющих данных мутаций.
Correlation of Biochemical Abnormalities with the Severity of Hospitalized Covid-19 Patients
Authors:   Sri Ramachandra Institute of Higher Education and Research, Silambanan Santhi , Koshy Teena ,   Sri Ramachandra Institute of Higher Education and Research, K. K Mahesh ,   Government Yoga and Naturopathy Medical College and Hospital, Ch. A Jasmine ,   Sri Ramachandra Institute of Higher Education and Research, Bhaskar Emmanuel ,   Sri Ramachandra Institute of Higher Education and Research, Moorthy Swathy ,   Sri Ramachandra Institute of Higher Education and Research
Published: June 2022

Background: Coronavirus Disease-19 (COVID-19) has a global impact. The laboratory assessments in Covid-19 illness help in better understanding the disease pathophysiology useful in screening asymptomatic individuals to diagnosis, prognosis and monitoring the affected patients. The aim of the study:To observe the association between biochemical and inflammatory parameters among the hospitalised COVID-19 patients of different clinical severity. Materials and methods: This was a retrospective study carried out with the approval of the Institutional Ethics Committee. The study included patients over 18 years, hospitalised with COVID-19 infection, grouped into three severity groups, admitted to ward, high dependency unit or intensive care unit between May to September 2020. Data collection was carried out by manual perusal of inpatient case sheets, computerised patient data system and transcription database for discharge summaries. The biochemical and inflammatory markers like plasma glucose, renal function tests, serum electrolytes, liver function tests, erythrocyte sedimentation rate (ESR), C-Reactive protein (CRP), d-dimer, ferritin, Lactate dehydrogenase (LDH) at the time of admission were collected. Data was expressed as mean and standard deviation or median and range. ANOVA test followed by post hoc (Tukey) test, Pearson correlation and Receiver Operating Characteristics (ROC) Curve analysis were performed. Results: Significant correlations were observed between the mild and moderate-severe illness groups with respect to fasting plasma glucose, blood urea nitrogen, creatinine, direct bilirubin, total protein, albumin, ferritin and LDH. The AUC was the highest for LDH at 0.64 followed by blood urea nitrogen to creatinine ratio at 0.62. Conclusion: High levels of renal function parameters were potential predictors of acute kidney injury among patients with COVID-19. Fasting plasma glucose, serum albumin, LDH, Blood urea nitrogen (BUN) and BUN-creatinine ratio are better indicators of the severity of the disease with multiorgan dysfunction.
Effects of Insect Growth Regulators on Ambrosia Beetles (Coleoptera: Curculionidae)
Authors: Joseph Shimat V. 
Published: June 2022

Abstract
Ambrosia beetles, especially the granulate ambrosia beetle, Xylosandrus crassiusculus (Motschulsky) (Coleoptera: Curculionidae), are serious pests in ornamental nurseries in Georgia during the spring months. Growers spray pyrethroid insecticides to prevent ambrosia beetle attacks on the tree trunk around bud break. Repeated pyrethroid insecticide applications can harm beneficial arthropods and cause a resurgence of minor, secondary pests. Insect growth regulators (IGRs), such as novaluron and azadirachtin, have demonstrated transovarial activity on many insect pests, for which the viability of the eggs was reduced after adult exposure. IGRs, particularly azadirachtin, are also repellent to many insect pests. Thus, the objective of this study was to determine the transovarial and repellent activity of IGRs on ambrosia beetles. Two experiments were conducted in ornamental nurseries in 2019 and 2021. In the first experiment, novaluron, azadirachtin, and permethrin were sprayed as stand-alone and combination treatments with permethrin on maple (Acer) tree bolts. The number of ambrosia beetle attacks was significantly lower in treatments with permethrin in both years. Novaluron and azadirachtin treatments neither reduced ambrosia beetle attacks on the ethanol-infused bolts nor suppressed the recovery of X. crassiusculus from the bolts, suggesting the lack of repellent and transovarial activity, respectively. For the second experiment, novaluron alone and in combination with 1×, 4×, and 8× bark penetrant at the label rate were sprayed on ethanol-infused bolts. None of the novaluron treatments with or without bark penetrant elicited transovarial activity in X. crassiusculus, as the beetle recovery was similar among treatments.
Lethal Toxicity of
Thymus capitatus
Essential Oil Against
Planococcus citri
(Hemiptera: Pseudococcidae) and its Coccinellid Predator
Cryptolaemus montrouzieri
(Coleoptera: Coccinellidae)
Authors: Alloui-Griza Rafika , Cherif Asma , Attia Sabrine , Francis Frederic , Lognay Georges C. , Grissa-Lebdi Kaouthar 
Published: June 2022

Abstract
Botanical extracts, including essential oils, are promising alternatives to synthetic insecticides for pest control. In this study, we evaluated the fumigant toxicity of an essential oil extracted from Thymus capitatus (L.) Hoffmanns. & Link against the citrus mealybug, Planococcus citri Risso (Hemiptera: Pseudococcidae), and its coccinellid predator Cryptolaemus montrouzieri Mulsant (Coleoptera: Coccinellidae) under laboratory conditions. Gas chromatography–mass spectrometry analysis indicated that the major chemical compounds identified from T. capitatus were carvacrol (65.15%), followed by p-cymene (11.79%) and γterpinene (7.48%). High mortality levels were registered for P. citri larvae (up to 100%) and adults (up to 96%) when exposed to the tested essential oil. The median lethal concentration values calculated for P. citri adults were higher than for larvae. Thymus capitatus essential oil applied at 10 and 20 µL/Lair showed high toxicity towards C. montrouzieri adults. These results highlighted the efficacy of T. capitatus essential oil as a promising tool to control P. citri in Tunisia. However, the adverse effects of this oil towards C. montrouzieri should be taken into consideration to enhance its practical implication in integrated pest management.
Correlation between the Use of Shared Goods with Pediculosis Capitis among Students in Pondok Pesantren Subulussalam Palembang
Authors: Sari Rifka Purnama , Handayani Dwi , Prasasty Gita Dwi , Anwar Chairil , Karim Fatmawati 
Published: June 2022

Pediculosis capitis is a parasitic infection caused by the parasite Pediculus humanus var. capitis, which commonly found in densely crowded areas such as boarding schools. It is possible to contract pediculosis capitis by coming into direct or indirect contact with sufferers' hair. The goal of this study was to assess the prevalence of pediculosis capitis in students at Pondok Pesantren Subulussalam Palembang, as well as the association between the use of shared goods and the occurrence of pediculosis capitis. This study is a cross-sectional observational analytic study including 116 students who live permanently in Pondok Pesantren Subulussalam Palembang. A questionnaire was used to collect data, as well as direct observation of hair samples. The Chi-Square test, Fisher's exact test, and logistic regression were used to examine the results. The findings revealed that 35.3% of people had pediculosis capitis, and that there was a significant association between the use of mattresses (p=0.007), combs (p=0.024), and shared veils (p=0.006) and the occurrence of pediculosis capitis. The use of combs (p=0.018) and shared veils (p=0.001) were the most influential variables on the occurrence of pediculosis capitis, according to the results of the logistic regression test. The spread of pediculosis capitis disease is predicted to be reduced and prevented with improved personal hygiene, environment sanitation, and treatment.
Keywords: Pediculosis capitis, boarding schools, Subulussalam, shared goods
APPLICATION OF MAGNETIC FIELDS IN SEVERAL MUSTARD VARIETIES WITH NFT HYDROPONIC SYSTEM ON GROWTH AND YIELD
Authors: Setiyono Setiyono , Dwiharjo Danu , Arum Ayu Puspita 
Published: June 2022

<p>Increasing total national mustard consumption encourages an increase in productivity for mustard cultivation in Indonesia, which is contradictory to the availability of land for mustard cultivation. Therefore, cultivation with the NFT Hydroponics system with the application of a magnetic field and using of the best varieties can be a solution to these problems. The magnetic field can accelerate seed germination and magnetized water. The purpose of this study was to determine the interaction of magnetic field application with varieties on the growth and yield of mustard using the NFT hydroponic system. This experiment used a split-plot design consisting of 2 factors and 3 replications. The magnetic field application as the main plot consisted of 2 levels, without magnetic field application (M0) and magnetic field application (M1), while the varieties as sub-plots consisted of 5 levels, Tosakan (V1), Shinta (V2), Dakota ( V3), IRR(V4) and Nauli F1 (V5). The observation variables were plant height, number of leaves, wet weight, dry weight, and root volume. The results showed, there was a significant interaction only on the number of leaves with the best treatment M1V5 (16 number of leaves). The magnetic field factor has a significant effect on all variables except dry weight. </p>
The Effect of Roughness on the Nonlinear Flow in a Single Fracture with Sudden Aperture Change
Authors: Chen Zhou , Tian Zhengying , Zhan Hongbin , Huang Jingtao , Huang Yong , Wei Yunbo , Ma Xing 
Published: June 2022

Abstract
Abrupt changes in aperture (sudden expansion and contraction) are commonly seen in naturally occurred or artificial single fractures. The relevant research mainly focuses on the changes in fluid properties caused by the sudden expansion of the aperture in smooth parallel fractures. To investigate the effects of roughness on the nonlinear flow properties in a single rough fracture with abruptly aperture change (SF-AC), the flow characteristics of the fractures under different Reynolds numbers Re (50~2000) are simulated by the turbulence k-ε steady-state modulus with the Naiver-Stokes equation. The results show that, in a rough SF-AC, the growth of the eddy and the flow path deflection of the mainstream zone are more obvious than those in a smooth SF-AC, and the discrepancies between the rough and smooth SF-ACs become even more obvious when the relative roughness and/or Re values become greater. The increase of the fracture roughness leads to the generation of more local eddies on the rough SF-ACs and enhances the flow path deflection in the sudden expansion fracture. The number of eddies increases with Re, and the size of eddy area increases linearly with Re at first. When Re reaches a value of 300-500, the growth rate of the eddy size slows down and then stabilizes. Groundwater flow in a rough SF-AC follows a clearly visible nonlinear (or non-Darcy) flow law other than the linear Darcy’s law. The Forchheimer equation fits the hydraulic gradient-velocity (J-v) better than the linear Darcy’s law. The corresponding critical Re value at which the nonlinear flow starts to dominate in a rough SF-AC is around 300~500.
Three-Dimensional Stochastic Distribution Characteristics of Void Fraction in Longwall Mining-Disturbed Overburden of Inclined Coal Seam
Authors: Wang Shaofeng , Liu Kanghui , Pi Zizi , Tian Fuchao , Yang Yalan 
Published: June 2022

Abstract
Fractures in the overburden induced by mining disturbances provide a channel for fluid flow between the surface and the underground. Mining-induced strata movement and fracture distribution are influenced by the gravity and dip angles of rock seams. In this paper, a new three-dimensional theoretical distribution model for void fraction in each partition of overlying rock strata disturbed by inclined coal seam mining was constructed. Based on the theoretical determination model, the three-dimensional random distribution characteristics for void fraction were obtained by combining the random distribution law of void fraction obtained by similar physical simulation experiments and image processing techniques. Theoretical deterministic models, stochastic theoretical models, and similar physical simulations all show that void fraction distribution in the tendency direction of the coal seam shows a bimodal asymmetric distribution with high and low peaks and a symmetric distribution in the strike direction. The void fraction of the overburden in the central part of the mining area is smaller than that of the surrounding area. The results of the theoretically determined model and stochastic model of the void fraction for the strata with different mining lengths and different coal seam inclinations were compared with the results of similar simulation experiments, respectively. The results are in agreement, further verifying the practicality of the model.
Provenance Discrimination of Siliciclastic Sediments in the Western Sea of Japan over the Past 30 kyr: Evidence from Major, Trace Elements, and Pb Isotopes
Authors: Dou Ruxi , Zou Jianjun , Shi Xuefa , Zhu Aimei , Dong Zhi , Zou Xinqing , Gorbarenko Serge 
Published: June 2022

Abstract
The Sea of Japan (JS), a unique marginal sea without any large river influxes in the western Pacific, provides ample information about the evolution of sea level, East Asian monsoons (EAM), sea ice activity, and ocean currents in geological time. However, insufficient investigation in the western JS limits our knowledge of East Asian climate change. This study utilizes major and trace elements and Pb isotopes of fine siliciclastic components (&lt;63 μm) of core LV53-18-2 and determines the provenances using statistical methods and discrimination diagrams. The results show that the terrigenous debris of LV53-18-2 was mainly composed of aeolian dust from northeast China, ice-rafted debris (IRD), and volcanic materials from the Far East coast over the last 30 kyr. During the late last glacial period, sea ice activity carried weakly weathered IRD to the study area. Meanwhile, the strengthened East Asian winter monsoon (EAWM) brought dust from northeast China to the study site owing to the cold climate and enlarged sandy land. During the late last deglacial period to early Holocene (15-8 kyr), ascending boreal summer insolation drove the intense melting of sea ice. This led to the deposition of large amounts of weakly weathered IRD and remarkably influenced the chemical composition of the core. After 8 kyr, the global sea level rose to -15 m below the modern sea level and opened the Tatar Strait. Consequently, freshwater supplied by the Amur River entered the JS and gave birth to the Liman Cold Current (LCC), which transported more mafic materials from the Kema terrane upstream.
Hollow and Oval-Configured Ultrafine Co3O4 as a Highly-Efficient Activator of Monopersulfate for Catalytic Elimination of Azorubin S
Authors: Khiem Ta Cong , Tuan Duong Dinh , Kwon Eilhann , Thanh Bui Xuan , Tsang Yiu Fai , Munagapati Venkata Subbaiah , Wen Jet-Chau , Hu Chechia , Lin Kun-Yi 
Published: June 2022

Abstract
As Azorubin S represents one of the most common and frequently-utilized toxic azo dyes produced from industrial activities, the ongoing release of this chemical substance from wastewater effluents into water systems may result in negative effects on microorganisms and human health. While various conventional treatment techniques could not effectively eliminate ARS from water, heterogeneous metal-based catalysts coupled with monopersulfate (MPS) is recently utilized as a highly-efficient process for eliminating ARS, in which tricobalt tetroxide (Co3O4) has been attracted increasing attention as a preeminent MPS activator due to its outstanding physicochemical properties, redox capability and excellent reactivity. However, the nanoscale Co3O4 particles usually pose a limitation of serious agglomeration in the aqueous environment, lowering their reactive surface, and efficiency. Thus, developing an easy-synthesized and exceptionally efficient Co3O4-based catalyst for MPS activation is crucially paramount. Therefore, in this work, a special hollow-structured oval-like Cobalt Oxide (abbreviated as HOCO) was successfully constructed using Co-MOF as a precursor, which was then utilized for catalyzing activation of MPS to degrade ARS. This as-obtained HOCO exhibited distinct physicochemical characteristics from commercially-available Co3O4, which subsequently result in superior activities for MPS activation in ARS degradation. From the experimental investigations, SO4•‒ radicals were validated to be primary reactive species for ARS degradation while the degradation pathway of ARS was also elucidated. This study further provides insightful information about the development of novel hollow-structured Co3O4-based catalyst for catalyzing activation of MPS to remove toxic dyes from water.
A novel proposal for all optical 1-bit comparator based on 2D linear photonic crystal
Authors: Parandin Fariborz , Askarian Asghar 
Published: June 2022

Abstract
In this paper, we are going to employ seven optical waveguides (OWGs) based on two-dimensional (2D) linear photonic crystal (LPhC) for realizing an all optical comparator (AOCMP). The proposed 1-bit AOCMP has a very simple structure with a footprint of 351 μm2 which is composed of 31 × 33 cubic lattice of silicon rods immersed in air. This LPhC comparator comprises two input ports and two output ports. The functionality of the proposed 1-bit AOCMP is based on constructive and destructive interference phenomenon of optical beams and phase shift keying technique. The finite difference time domain (FDTD) procedure based on Yee’s Algorithm is used to compute the propagation of optical waves in this structure. The FDTD simulation results of suggested 1-bit AOCMP indicate that the minimum and maximum values of the normalized power (NP) at ON and OFF states for output ports are 73% and 15%, respectively. Also, the ON-OFF contrast ratio (CR), bit rate (BR), rise and fall times (Tr and Tf) of the suggested design are about 6.87 dB, 2.22 Tb/S, 0.15ps and 0.05ps, respectively.
Impact of shading net on microclimate condition in orchards
Authors: MOMENI Davood 
Published: June 2022

Abstract
Due to various reasons such as climatic stresses, pest attacks, disease outbreaks, damage caused by insects and birds, etc., irreparable damages are done to fruit trees. One of the operational solutions in the world to reduce these injuries is the use of shading net in the gardens. In order to select the appropriate shading net, it is necessary to first determine the main factors required for plant growth and development so that the installed net does not have an adverse effect on them. In this research, changes in radiation, temperature, wind velocity, wind direction and relative humidity inside and outside of two shadehouse garden were monitored. Investigating of the graphs in temperature, relative humidity and light changing throughout the period indoor shadehouse gardens showed that the temperature inside the shading net was lower than outside but no significant differences were observed between the months. Regarding relative humidity and light, both parameters were more and less than outside, respectively, but no significant differences were observed between the months. In general, the study of changes in the mean of the three parameters of temperature, humidity and radiation in the whole period showed that the greatest effect of using shading nets on microclimate in gardens was on reducing the intensity of light received. Also when the wind velocity is high, the temperature inside and outside the shading net is closer to each other.