bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acquired cystic kidney disease in children with kidney failure
Authors: Ma Justin Ming-yin , Fung Kin-fen Kevin , Tong Pak-Chiu , Lai Wai-ming , Ma Alison Lap-tak , Chan Eugene Yu-hin 
Published: January 2025

Abstract
Background
This study aimed to evaluate the incidence, contributing factors, and clinical outcomes of acquired cystic kidney disease (ACKD) in children undergoing kidney replacement therapy (KRT).

Methods
We conducted a cross-sectional, territory-wide study at the designated pediatric nephrology center in Hong Kong. ACKD was defined as the presence of ≥ 3 cysts in the native kidneys, excluding congenital or hereditary cystic diseases. Between June to December 2023, all paediatric patients receiving KRT in Hong Kong underwent ultrasonography, non-contrast magnetic resonance imaging (MRI), or both. Contrast-enhanced computed tomography was performed for patients with complex cysts.

Results
Forty-three children (56% female; median age 14.7 years; IQR, 11.7–18.7) were included in the analysis. ACKD was detected in 18 children (42%). Nine subjects had complex cysts (grade 2, n = 5; grade 2F, n = 2; grade 3, n = 2). Most patients with ACKD (89%) were asymptomatic. One patient (5.5%) developed back pain and gross haematuria 72 months after initiation of KRT. Another patient (5.5%) developed infected cyst with back pain and clinical sepsis 60 months following KRT initiation. A dialysis duration of ≥ 28 months was the only significant factor associated with ACKD development (77.8% vs. 40%; p = 0.028; ORadj 6.09, 95% CI 1.43–25.82, p = 0.014). The diagnostic yield of paired ultrasound and MRI was superior to ultrasound alone.

Conclusions
ACKD is prevalent among children and adolescents with kidney failure, with most cases being asymptomatic, however serious complications may arise. Longer duration of dialysis is significantly associated with ACKD development. Therefore, early transplantation and active ACKD surveillance are crucial for children receiving KRT.

Graphical abstract
A novel energy-based modeling framework
Authors: Altmann R. , Schulze P. 
Published: January 2025

AbstractWe introduce an energy-based model, which seems especially suited for constrained systems. The proposed model generalizes classical port-Hamiltonian input–state–output systems and exhibits similar properties such as energy dissipation as well as structure-preserving interconnection and Petrov–Galerkin projection. In terms of time discretization, the midpoint rule and discrete gradient methods are dissipation-preserving. Besides the verification of these properties, we present ten examples from different fields of application illustrating the great flexibility of the proposed framework.
Revisiting recommender systems: an investigative survey
Authors: Ibrahim Osman Ali Sadek , Younis Eman M. G. , Mohamed Ebtsam A. , Ismail Walaa N. 
Published: January 2025

Abstract
This paper provides a thorough review of recommendation methods from academic literature, offering a taxonomy that classifies recommender systems (RSs) into categories like collaborative filtering, content-based systems, and hybrid systems. It examines the effectiveness and challenges of these systems, such as filter bubbles, the "cold start" issue, and the reliance on collaborative filtering and content-based approaches. We trace the development of RSs, emphasizing the role of machine learning and deep learning models in overcoming these challenges and delivering more accurate, personalized, and context-aware recommendations. We also highlight the increasing significance of ethical considerations, including fairness, transparency, and trust, in the design of RSs. The paper presents a structured literature review, discussing various aspects of RSs, such as collaborative filtering, personalized recommender systems, and strategies to improve system robustness. It also points out the limitations of the existing approaches and suggests promising research directions for the future. In summary, this paper offers a comprehensive analysis of RSs, focusing on their evolution, challenges, and potential future improvements, particularly in enhancing accuracy, diversity, and ethical practices in recommendations.
Virtual reality game-based training for preventing falls among community-dwelling older adults with mild cognitive impairment: a pilot randomized control trial study
Authors: Ip Wing Keung , Soar Jeffrey , James Christina , Wang Szu-Yao , Fong Kenneth N. K. 
Published: January 2025

AbstractUsing a Virtual Reality (VR) game-based application represents an innovative approach to falls prevention in community aged care service. The study investigated the effects of VR training on falls prevention among community-dwelling older adults with mild cognitive impairment. A pilot randomized controlled trial was conducted to compare the effects of full-immersive VR training with group-based exercise (Baduanjin) training on falls prevention. Eighteen participants were recruited through convenience sampling and were randomly assigned to either the VR group or the non-VR exercise group. Both groups participated in 16 falls prevention training sessions over eight weeks. Participants, identified with mild cognitive impairment (MCI), underwent three fall risk measurements. They had been screened using Montreal Cognitive Assessment (HK-MoCA). The primary outcomes assessed included changes in physical risk factors of falls (i.e. functional mobility, walk speed and postural balance), and the secondary outcomes assessed included changes in executive function and fall efficacy. The measurement of physical outcomes was Time Up and Go test (TUG), Berg balance scale (BBS) and Six-minute Walk Test (6MWT). The participants’ executive function and fear of falling were assessed through the Trail marking test (TMTA and TMTB) and the Fall Efficacy International scale (FES-I). The results showed that the VR group had significantly greater improvement than the non-VR group on measures of cognitive-motor performance, such as global cognition, functional mobility, balance and walk speed over time. However, no significant differences were observed between the two groups in executive functions and the fall efficacy. The study provides potential evidence that VR game-based cognitive-motor training can be effective for fall prevention in community dwelling older adults with MCI. However, the findings do not support significant improvements in secondary outcomes. Despite this, the growing trend of VR research suggests increasing interest and potential for future applications in aged care and rehabilitation services.
Higher rank prioritary bundles on ruled surfaces and their global sections
Authors: Costa L. , Tarrío I. Macías 
Published: January 2025

AbstractLet X be a ruled surface over a nonsingular curve C of genus $$g\ge 0$$

g
≥
0

. The main goal of this paper is to construct simple prioritary vector bundles of any rank r on X and to give effective bounds for the dimension of their module of global sections.
A quality assurance protocol for reliable and reproducible multi-TI arterial spin labeling perfusion imaging in rat livers
Authors: Zhao Wan-Ting , Herrmann Karl-Heinz , Wei Weiwei , Krämer Martin , Dahmen Uta , Reichenbach Jürgen R. 
Published: January 2025

Abstract
Objective
To establish an arterial spin labeling (ASL) protocol for rat livers that improves data reliability and reproducibility for perfusion quantification.

Methods
This study used respiratory-gated, single-slice, FAIR-based ASL imaging with multiple inversion times (TI) in rat livers. Quality assurance measures included: (1) introduction of mechanical ventilation to ensure consistent respiratory cycles by controlling the respiratory rate (45 bpm), tidal volume (10 ml/kg), and inspiration: expiration ratio (I:E ratio, 1:2), (2) optimization of the trigger window for consistent trigger points, and (3) use of fit residual map and coefficient of variance as metrics to assess data quality. We compared image quality, perfusion maps, and fit residual maps between mechanically ventilated and non-ventilated animals, as well as repeated ASL measurements (session = 4 per animal) in two mechanically ventilated animals.

Results
Perfusion measurements over multiple sessions in mechanically ventilated rats exhibited low perfusion data variability and high reproducibility both within and between liver lobes. Image quality and perfusion maps were significantly improved in mechanically ventilated animals compared to non-ventilated animals.

Discussion
The implementation of mechanical ventilation and optimized quality assurance protocols enhanced the reliability and reproducibility of FAIR-based multi-TI-ASL imaging in rat livers. Our findings demonstrate these measures as a robust approach for achieving consistent liver perfusion quantification in preclinical settings.
A data-centric framework for combating domain shift in underwater object detection with image enhancement
Authors: Folkman Lukas , Pitt Kylie A. , Stantic Bela 
Published: January 2025

Abstract
Underwater object detection has numerous applications in protecting, exploring, and exploiting aquatic environments. However, underwater environments pose a unique set of challenges for object detection including variable turbidity, colour casts, and light conditions. These phenomena represent a domain shift and need to be accounted for during design and evaluation of underwater object detection models. Although methods for underwater object detection have been extensively studied, most proposed approaches do not address challenges of domain shift inherent to aquatic environments. In this work we propose a data-centric framework for combating domain shift in underwater object detection with image enhancement. We show that there is a significant gap in accuracy of popular object detectors when tested for their ability to generalize to new aquatic domains. We used our framework to compare 14 image processing and enhancement methods in their efficacy to improve underwater domain generalization using three diverse real-world aquatic datasets and two widely used object detection algorithms. Using an independent test set, our approach superseded the mean average precision performance of existing model-centric approaches by 1.7–8.0 percentage points. In summary, the proposed framework demonstrated a significant contribution of image enhancement to underwater domain generalization.
Novel Selective Cardiac Myosin-Targeted Inhibitors Alleviate Myocardial Ischaemia–Reperfusion Injury
Authors: Yusof Nur Liyana Mohammed , Yellon Derek M. , Davidson Sean M. 
Published: January 2025

Abstract
Purpose
Reperfusion of the ischaemic heart is essential to limit myocardial infarction. However, reperfusion can cause cardiomyocyte hypercontracture. Recently, cardiac myosin-targeted inhibitors (CMIs), such as Mavacamten (MYK-461) and Aficamten (CK-274), have been developed to treat patients with cardiac hypercontractility. These CMIs are well tolerated and safe in clinical trials. We hypothesised that, by limiting hypercontraction, CMIs may reduce hypercontracture and protect hearts in the setting of ischaemia and reperfusion (IR).

Methods
We investigated the ability of MYK-461 and CK-274 to inhibit hypercontracture of adult rat cardiomyocytes (ARVC) in vitro following ATP depletion. A suitable dose of CMIs for subsequent in vivo IR studies was identified using cardiac echocardiography of healthy male Sprague Dawley rats. Rats were anaesthetized and subject to coronary artery ligation for 30 min followed by 2 h of reperfusion. Prior to reperfusion, CMI or vehicle was administered intraperitoneally. Ischaemic preconditioning (IPC) was used as a positive control group. Infarct size was assessed by tetrazolium chloride staining and extent of hypercontracture was assessed by histological staining.

Results
Treatment with CMIs inhibited ARVC hypercontracture in vitro. MYK-461 (2 mg/kg) and CK-274 (0.5 mg/kg to 2 mg/kg) significantly reduced infarct size vs. vehicle. IR caused extensive contraction band necrosis, which was reduced significantly by IPC but not by CMIs, likely due to assay limitations. GDC-0326, an inhibitor of PI3Kα, abrogated CK-274-mediated protection following IR injury. GDC-0326 reduced phosphorylation of AKT when administered together with CK-274.

Conclusion
This study identifies CMIs as novel cardioprotective agents in the setting of IR injury.
Design and fabrication of mesh-like four-warp leno cotton fabric based on self-locking effect: outstanding mechanical performance and breathability
Authors: Tian Xiao , Yao Meiyu , Li Ying , Li Li 
Published: January 2025

Abstract
Achieving a fabric with good mechanical performance and breathability is significant for the development of protective clothing. The leno structure is a desirable fabric design for enhancing these properties due to its advantageous characteristics, such as flexibility, lightness, diamond-shaped structure, and increased yarn interlacing. However, there is a lack of studies focused on developing novel leno structures because of the difficulty of weaving and exploring the mechanical behavior and breathability of various leno fabrics with different structural characteristics. In this study, we leveraged advanced weaving techniques with improved needle-shaped heald frames to develop a programmed mesh-like four-warp leno cotton fabric that offers outstanding mechanical performance and breathability. The efficacy of the self-locking effects, achieved by manipulating the yarn interweaving to simultaneously regulate yarn friction and fabric porosity, is experimentally demonstrated. Compared to plain structures of the same density, the four-warp leno (FL) fabric exhibits nearly twice the tensile strength and strain in the warp direction. Additionally, the four-warp leno fabric demonstrates greater displacements to reach the junction rupture force point than plain structure of the same density in the yarn pull out tests, owing to the self-locked interweaving of the warp yarns. The yarn pull-out behavior of the FL was analyzed to illustrate the variation in load and displacement. Moreover, the high porosity of the four-warp leno woven fabric results in excellent air permeability, thermal conductivity, and water vapor transmission. This study provides an effective strategy for designing and fabricating four-warp leno fabric with outstanding mechanical performance and breathability for diverse applications.
Near real-time change detection tool for photogrammetric flood preparedness
Authors: Kögel Michael , Carstensen Dirk 
Published: January 2025

Abstract
Through the mobilization of movable objects due to the extreme hydraulic conditions during a flood event, blockages, damage to infrastructure, and endangerment of human lives can occur. To identify potential hazards from aerial imagery and take appropriate precautions, a change detection tool (CDT) was developed and tested using a study area along the Aisch River in Germany. The focus of the CDT development was on near real-time analysis of point cloud data generated by structure from motion from aerial images of temporally separated surveys, enabling rapid and targeted implementation of measures. The differences identified in the study area using distance comparison (M3C2) were segmented into individual components and categorized. Subsequently, the data was compared to existing two-dimensional hydrodynamic numerical calculation results (HQ100). The implementation of the CDT is feasible for a variety of RGB camera-equipped aerial vehicles due to the point cloud-based analysis and postprocessing. By overlaying and visualizing the detected changes with numerical simulation results, a quick assessment of the hazard potential in the event of a possible flood can be made. In the case of the study area along the Aisch River, the localization of construction materials, a steel container with debris pile, and a motor vehicle in the flood hazard zone of a potential HQ100 event could be confirmed, although no mobilization of the materials was to be expected due to the expected hydraulic conditions of a flood event.
The Aberrant Behavior Checklist in a Clinical Sample of Autistic Individuals with Intellectual Disabilities and Co-Occurring Mental Health Problems: Psychometric Properties, Factor Structure, and Longitudinal Measurement Invariance
Authors: Kildahl Arvid Nikolai , Hellerud Jane Margrete Askeland , Halvorsen Marianne Berg , Helverschou Sissel Berge 
Published: January 2025

AbstractThe Aberrant Behavior Checklist (ABC) was originally developed to evaluate interventions, and is a well-established assessment tool for challenging behaviours in people with intellectual disabilities and autistic people. However, whether the ABC displays longitudinal measurement invariance (i.e., whether it captures the same constructs over time) has been sparsely explored. The aim of the current study is to explore the factor structure, longitudinal measurement invariance, and clinical correlates of the ABC in autistic individuals with intellectual disabilities. Using data from a multicentre study of mental health assessment and treatment in autistic people with intellectual disabilities, the intake ABC scores of 200 autistic individuals with intellectual disabilities were used to explore the ABC factor structure, internal consistency, and clinical correlates (age, gender, level of intellectual disability, autism characteristics, communication skills). Scores across three time points (intake, post-intervention, follow-up) were used to explore longitudinal measurement invariance and internal consistency over time. The original five-factor structure showed a non-optimal but acceptable fit, which was similar or slightly improved compared to previous studies. Associations for some ABC subscales were found to be positive for autism characteristics and negative for communication skills. Four of the five subscales (irritability, social withdrawal, stereotypic behaviour, inappropriate speech) showed residual levels of longitudinal measurement invariance, while one subscale showed noninvariance (hyperactivity/noncompliance). The current study demonstrates the construct validity and applicability of the ABC in autistic individuals with intellectual disabilities, while also indicating that caution is advised for one of its subscales in comparisons across time.
Wellbeing and the Lived Experience of Injured Workers Following Finalisation of a Workers’ Compensation Claim
Authors: Weir James , Fary Robyn , Lee Samantha , Mitchell Tim , Johnston Venerina , Wyatt Mary , Guthrie Robert , Myers Bronwyn , Beales Darren 
Published: January 2025

Abstract
Purpose
Workers’ compensation claims can negatively affect the wellbeing of injured workers. For some, these negative effects continue beyond finalisation of the workers’ compensation claim. It is unclear what factors influence wellbeing following finalisation of a workers’ compensation claim. Therefore, the aim of this study was to explore wellbeing through the lived experience of individuals who have finalised a workers’ compensation claim in the state of Western Australia.

Methods
A qualitative study with individual, in-depth, semi-structured interviews was performed (n = 20, 55% female, average claim length 22.9 months, average time since claim end 33.4 months). Claim finalisation modes included full medical recovery, claim settlement with permanent impairment, direct settlement with the insurer and settlement with the insurer facilitated by a lawyer. The interview schedule was informed by a previous scoping review and cross-sectional survey completed by this research team. Qualitative data were analysed utilising a reflexive, interpretative phenomenological analysis approach.

Results
Five superordinate and their associated subordinate themes were identified; (1) The role of support; (2) Stigma and discrimination; (3) A new normal; (4) The importance of information; and (5) Recommended resources.

Conclusions
Injured workers experience a range of outcomes related to their wellbeing and employment following the finalisation of their workers’ compensation claim. Based on their experiences, resources to facilitate a transition and adjustment to life following a claim have been suggested by injured workers, including information regarding seeking employment, seeking welfare support, educational materials regarding future expectations, and individualised support care packages.
Maximal line-free sets in $$\mathbb {F}_p^n$$
Authors: Elsholtz Christian , Führer Jakob , Füredi Erik , Kovács Benedek , Pach Péter Pál , Simon Dániel Gábor , Velich Nóra 
Published: January 2025

Abstract
We study subsets of

$$\mathbb {F}_p^n$$

F
p
n

that do not contain progressions of length

$$k$$

k

. We denote by

$$r_k(\mathbb {F}_p^n)$$

r
k

(

F
p
n

)

the cardinality of such subsets containing a maximal number of elements. In this paper we focus on the case

$$k=p$$

k
=
p

and therefore sets containing no full line. A trivial lower bound

$$r_p(\mathbb {F}_p^n)\ge (p-1)^n$$

r
p

(

F
p
n

)

≥

(
p
-
1
)

n

is achieved by a hypercube of side length

$$p-1$$

p
-
1

and it is known that equality holds for

$$n\in \{1,2\}$$

n
∈
{
1
,
2
}

. We will however show that

$$r_p(\mathbb {F}_p^3)\ge (p-1)^3+p-2\sqrt{p}$$

r
p

(

F
p
3

)

≥

(
p
-
1
)

3

+
p
-
2

p

, which is the first improvement in the three-dimensional case that is increasing in

$$p$$

p

. We will also give the upper bound

$$r_p(\mathbb {F}_p^{3})\le p^3-2p^2-(\sqrt{2}-1)p+2$$

r
p

(

F
p
3

)

≤

p
3

-
2

p
2

-

(

2

-
1
)

p
+
2

as well as generalizations for higher dimensions. Finally, we present some bounds for individual

$$p$$

p

and

$$n$$

n

, in particular

$$r_5(\mathbb {F}_5^{3})\ge 70$$

r
5

(

F
5
3

)

≥
70

and

$$r_7(\mathbb {F}_7^{3})\ge 225$$

r
7

(

F
7
3

)

≥
225

which can be used to give the asymptotic lower bound

$$4.121^n$$

4
.

121
n

for

$$r_5(\mathbb {F}_5^{n})$$

r
5

(

F
5
n

)

and

$$6.082^n$$

6
.

082
n

for

$$r_7(\mathbb {F}_7^{n})$$

r
7

(

F
7
n

)

.
Borderline personality disorder and moral responsibility
Authors: Baehni Agnès 
Published: January 2025

Abstract
This paper seeks to determine the extent to which individuals with borderline personality disorders can be held morally responsible for a particular subset of their actions: disproportionate anger, aggressions and displays of temper. The rationale for focusing on these aspects lies in their widespread acknowledgment in the literature and their plausible primary association with blame directed at BPD patients. BPD individuals are indeed typically perceived as “difficult patients” (Sulzer 2015:82; Bodner et al. 2011), significantly more so than schizophrenic or depressive patients (Markam 2003). The “responsibility question” for patients with BPD has already been raised (Martin 2010; Zachar and Potter 2009; Bray 2003), but this paper tackles it from a novel perspective. First, I narrow down the category of things for which the responsibility question is specific to individual with BPD. After that, I argue that some of the diagnosis criteria of BPD such as emotional instability or impulsivity might serve as excusing factors targeting the “control condition” on moral responsibility. Second, this paper also considers another widely accepted condition on moral responsibility: the epistemic condition. The view defended in the paper is that the answer to the responsibility question for individuals with BPD, concerning both the control condition and the epistemic condition, hinges on an understanding of their epistemic profile.