bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of Compound Flooding Risk in Ise and Mikawa Bays, Japan Using a Framework of Atmosphere-Ocean-River Coupling
Authors: Toyoda Masaya , Mori Nobuhito , Kim Sooyoul , Shibutani Yoko , Yoshino Jun 
Published: December 2022

Abstract

The present study evaluated the compound flood risk of 11 different-sized rivers in the estuaries of the Ise and Mikawa Bays, Japan, using an integrated framework of atmosphere-ocean-river developed in this study. First, the framework was developed by incorporating the river channel into a coupled model of surge-wave-tide to include the interaction of the storm surge runup and river flow. In addition, the framework was validated by the Typhoon Trami (2018)-induced meteorological field, discharge, and storm surge with high accuracy. Then, the time difference between the storm surge and discharge at the estuary (TDSD) was investigated assuming six typhoons with different tracks and similar distributions of intensity and precipitation using Typhoon Hagibis (2019) as a case study. It was found that the TDSD reveals a high positive correlation with the length of the river channel (correlation coefficient: 0.90). Also, the smaller rivers were more prone to simultaneous storm surge and high river flow. The river with the smallest TDSD average in 6 cases of sensitivity experiments was 70 minutes, and it was clarified that the storm surge and high river flow occur simultaneously (within 15 min) in the most severe case (the smallest TDSD case). As a result, it was found that the small- and medium-sized river with a standard deviation of 49.5 minutes has a small TDSD regardless of the typhoon track, resulting in a higher risk of compound flood in comparison to the large-scale rivers with that of 102 minutes.
A Review on Food Subsystem Simulation Models for The Water-Food-Energy: Development Perspective
Authors: Variani Hossein Akbari , Afshar Abbas , Vahabzadeh Masoud , Molajou Amir 
Published: December 2022

Abstract
The interactions and trade-offs between Water, Food, and Energy (WFE) have recently attracted the attention of researchers worldwide. A new approach called nexus has been used to examine these interactions in an integrated way. A significant obstacle to adopting the WFE nexus is the lack of a comprehensive and easy-to-use simulation model. By reviewing the articles in Scopus and Google Scholar databases, WFE nexus studies can be divided into two categories: simulation-based and conceptual-based studies of WFE nexus. Based on developmental perspective on food subsystem modeling in WFE nexus, the conceptual studies excluded and the modeling studies reviewed. Two points of view can be used for WFE nexus modeling: 1. Hard-link modeling and 2. Soft-link modeling. Comparing these two types of modeling showed that Hard link modeling cannot model the interrelations of the food subsystem and this shortcoming is of great importance. Agriculture is the primary source of food supply because livestock and poultry products are also indirectly dependent on agricultural products. This study reviewed the crop growth models (CGMs) used in the WFE nexus system from the development perspective. The technical characteristics of the CGMs have been evaluated according to the requirements of the CGMs. Finally, a checklist based on the criteria defined for the nexus system has been provided, which can guide researchers in choosing the appropriate simulation model for the food subsystem with the nexus approach. Also, future research suggestions were recommended to develop a food subsystem simulation model based on nexus system approach criteria.
Virulence and pathogenic variability of wheat leaf blotch (Zymoseptoria tritici) isolates in Oromia, Ethiopia
Authors: Tarafa Girma Ababa , Adugna Girma , Hundie Bekele , Mekonnen Tilahun 
Published: December 2022

Abstract

Wheat leaf blotch caused by Zymoseptoria tritici (Zt) is a fungal disease that poses a severe danger to wheat production worldwide. Knowing the virulence diversity of this pathogen is crucial for taking effective control measures. However, there have been a few studies on Ethiopia pathogenic variability and pathotypes based on physiological specialization. Therefore, the goal of this study was to look at the virulence, spectrum, and population variability of Zt isolates. In a completely randomized design, 43 isolates in three replications were tested for their virulence and pathotypes against 7 wheat differential lines. The least significant difference method was used to identify specific virulence; whereas, pathotypes, principal components, and cluster analysis were used to study the pathogenic diversity. Then, virulence assay detected 41 differential lines specific virulence and 220 differential lines specific avirulence, among all (n = 301) interactions based on pycnidia parameter. Some of the isolates showed a considerable virulence spectrum on 4 (57.1%) and 5 (71.4%) differential lines based on pycnidia and leaf necrosis respectively; but, most of them were partial virulent on the differential lines. Based on pycnidia parameter: EtA-11, EtSh-1, EtSh-2, EtSh-4, and EtA-19 isolates expressed the virulent reaction on 3–4 differential lines; hence, useful for germplasm screening. Over, from this parameter, 25 pathotypes were ensued in which indicated 58.1% pathogenic diversity; moreover, the principal component analaysis detected 62.2% pathogenic diversity of Ethiopian isolates. Therefore, further virulence variability investigations employing isolates*wheat species specificity and molecular analysis are important. Wheat breeders and wheat farmers would find the results from this study extremely useful for making informed decisions on how to manage Zt disease. Again, it is crucial to examine the virulence diversity of Zt isolates using pathotype and principal component analysis.
FSCN1 promotes proliferation, migration and glycolysis via the IRF4/AKT signalling pathway in oral squamous cell carcinoma
Authors: Li Liang , Chen Lihui , Li Zhangwei , Huang Shiqin , Chen Yaoyao , Li Zhiyong , Chen Wenkuan 
Published: December 2022

Abstract
Background: Oral squamous cell carcinoma (OSCC) is an increasing disease worldwide that leads to lethal and deforming consequences. In OSCC, Fascin actin-bundling protein 1 (FSCN1) is identified as an oncogene involved in the tumorigenesis process. But the functions as well as potential mechanisms of FSCN1 in OSCC tumorigenesis process have not been reported so far.
Methods: We used RNA sequencing to detect the expreesion of FSCN1 from 40 paired OSCC tissue specimens (Tumor) and neighboring noncancerous tissue. Further colony formation, CCK-8 as well as transwell assay was performed to demonstrate the role of FSCN1 in vitro. Moreover, glucose consumption was detected. Western blot was used to confirm the interaction of FSCN1, IRF4 and AKT.
Results: FSCN1 was remarkably overexpressed in OSCC cell lines as well as tissues. Further colony formation, CCK-8 as well as transwell assay suggested that FSCN1 silencing remarkably dampened OSCC growth and migration. Detection of glycolytic metabolism showed that FSCN1 silence remarkably suppressed OSCC glycolysis. Following mechanism studies revealed that FSCN1 realized its functions in OSCC process partially through the interferon regulatory factor 4 (IRF4) and AKT activation.
Conclusion: In conclusion, our study investigated the functions as well as the mechanisms of the FSCN1/IRF4/AKT pathway in OSCC progression. FSCN1 could act as a prospective biologic signature and therapeutic target molecule for OSCC.
Occult intraocular aluminum foreign body causing Rhegmatogenous retinal detachment:A case report
Authors: Zhang Ling , Chen Bin , He WeiMin 
Published: December 2022

Abstract
Background: Ocular trauma is complex and varied, and some occult intraocular foreign bodies(IOFB) can lead to uncommon symptoms and signs. We report a case of rhegmatogenous retinal detachment (no obvious wound, no pain,no intraocular infection and other symptoms) caused by an occulted intraocular aluminum foreign body, which could easily been missed without careful preoperative examination.It has not been reported to our knowledge.
Case presentation: A 42-year-old male presented to the outpatient department of our hospital complaining black dots fluttered and decreased vision of his left eye initiated 3 months earlier.He was diagnosed as "floaters " at a community hospital. He denied history of ocular trauma or previous surgery.The cornea and lens of the left eye were clear.A small patch of pigmentation was noted in the temporal sclera. Fundoscopy revealed macula off retinal detachment.After mydriasis, elliptical holes were seen in the peripheral retina at 2:30,suspicious strip of hyperreflectance was found under the retina of the anterior lip under Goldmann three mirror contact lens examination, which was confirmed to be IOFB by orbital CT.The IOFB was removed through the pars plana vitrectomy without any complications.
Conclusion: Unlike iron and copper, aluminum intraocular foreign bodies are more inert and more likely to be missed.For people with special occupations (such as construction workers, mechanic, etc.), when abnormal pigmentation of the sclera is found, the possibility of foreign bodies in the eye should be vigilant.It is necessary, in the process of disease diagnosis and treatment,to ask detailed history including occupation history and practice, careful physical examination and targeted examination.Such comprehensive analysis of the above information will minimize the chance of missed diagnosis.
Health-Seeking Behavior Regarding Schistosomiasis Treatment in the Absence of a Regular Mass Drug Administration (MDA) Program: The Case of Endemic Communities Along Lake Albert in Western Uganda
Authors: Anyolitho Maxson Kenneth , Nyakato Viola Nilah , Huyse Tine , Poels Karolien , Masquillier Caroline 
Published: December 2022

Abstract

Introduction

Schistosomiasis poses a serious public health and social challenge affecting over 240,000,000 people, the majority of whom live in sub-Saharan Africa. Although the World Health Organization (WHO) recommends praziquantel (PZQ) drug treatment through regular mass drug administration (MDA), in endemic areas, it is hindered by funding gaps. We explored the health seeking behaviors of communities along Lake Albert in Western Uganda, regarding schistosomiasis treatment in the absence of a regular MDA program.

Methods and Materials

We conducted a community-based qualitative study. We interviewed 12 local leaders, village health teams, and health workers and conducted 28 focus group discussion sessions with 251 purposively selected community members. The audio recordings of the data were transcribed and analyzed using a thematic analysis model.

Results

Generally, participants seldom seek medication for schistosomiasis-related signs and symptoms from government hospitals and health centers II, III and IV despite their availability; instead, they rely on the MDA program and, in its absence, private clinics and drug shops nearby or traditional sources like which doctors and herbalists. The absence of PZQ drugs in the government health facility, health workers’ negative attitude towards patients, long distances to the government hospitals and health facilities, poor and inaccessible roads, medication-related costs, and negative perceptions of the PZQ drug informed by past experiences with MDA force people to seek medication from sources other than the government.

Conclusions

Availability and accessibility of PZQ seem to be a big challenge, especially for endemic communities such as Kagadi and Ntoroko. But even when it is available at government hospitals and health facilities, its uptake is hampered by health systems, and community-related and socio-cultural factors. Thus there is a need to bring schistosomiasis drug treatment and services closer to endemic communities and stock nearby facilities with PZQ. At the same time, endemic communities should be encouraged to take PZQ as the prevalence of schistosomiasis in the lake area is very high. Contextualised awareness-raising campaigns are needed to debunk myths and misconceptions surrounding the drug.
Evaluating the feasibility and preliminary efficacy of a Cognitive Occupation-Based programme for people with Multiple Sclerosis (COB-MS): an update to the protocol for a feasibility cluster-randomised controlled trial.
Authors: Dwyer Christopher P , Alvarez-Iglesias Alberto , Joyce Robert , Counihan Timothy J , Casey Dympna , Hynes Sinéad M 
Published: December 2022

Abstract
Background

Cognitive difficulties experienced by people with MS impact on quality of life and daily functioning, from childcare and work, to social and self-care activities. The COB-MS was developed as a holistic, individualised cognitive rehabilitation intervention to address the wide-ranging symptoms and functional difficulties that present in MS, including the ability to maintain employment, social activities, home management and self-care. The aim of the research is to evaluate the feasibility and preliminary efficacy of COB-MS for people with MS.

Methods

One hundred and twenty people with MS will be assigned to participate in either the COB-MS programme or a treatment as usual, wait-list control group as part of this single-blind, cluster-randomised controlled feasibility and preliminary efficacy trial of the COB-MS programme. The COB-MS group will participate in an eight session occupational-based cognitive rehabilitation programme over nine weeks. The primary outcome measure is the Goal Attainment Scaling at 12 weeks. Participants will be assessed pre-intervention, post-intervention, 12 weeks post-intervention and six months post-intervention. Qualitative evaluations of participants’ perspectives will also be examined as part of the feasibility study. Due to the impacts of COVID-19, all of the above trial activities were completed remotely. Data was collected online or by post and the COB-MS intervention was delivered online by occupational therapists to small groups of people with MS.

Discussion

Results will provide recommendations for a future definitive trial of COB-MS, with respect to both feasibility and preliminary, clinical efficacy.
Trial registration number: ISRCTN, ISRCTN11462710, Registered 9th September 2019, https://doi.org/10.1186/ISRCTN11462710 and updated on 23th September 2020 to account for changes outlined here.
Effects of Inaudible Binaural Beats on Visuospatial Memory
Authors: Kim Ye-Jin , Kim Kyu-Beom , Kim Ji-Su , Kim Hyung-Sik , Choi Mi-Hyun , Yi Jeong-Han , Chung Soon-Cheol 
Published: December 2022

Abstract

Background
Binaural beats (BB) are a form of auditory beat stimulation that produces sounds and can induce a specific state of brain wave based on the difference in the frequency of auditory stimulation. This study aimed at investigating the effects of inaudible BB on visuospatial memory at 18,000 Hz reference and 10 Hz difference frequencies.
Methods
Eighteen adult subjects in their twenties were enrolled, including 12 males (mean age: 23.8 ± 1.2) and six females (mean age: 22.8 ± 0.8). An auditory stimulator that could provide 10 Hz BB stimulation via 18,000 Hz to the left and 18,010 Hz to the right ears was used. The experiment consisted of two 5-minute phases, the rest and task phases. The task phase involved two conditions: task performance without BB stimulation (Task-only) and with BB stimulation (Task + BB). A 3-back task was used to measure visuospatial memory. Throughout the experiment, brain waves were measured at a 500 Hz sampling rate. Cognitive ability as measured by task performance (accuracy and reaction time) with and without BB, as well as variations in alpha power across different brain domains were compared using paired t-tests.
Results
The results show that, compared to the Task-only condition, the Task + BB condition had significantly higher accuracy and significantly shorter reaction time. The electroencephalogram (EEG) analysis showed that a reduction level in alpha power for the task performance under the Task + BB condition was significantly lower in all brain areas except the frontal, compared to that under the Task-only condition.
Conclusion
The significance of this study lies in having verified the independent effects of BB stimulation without any auditory influence, based on visuospatial memory.
Surgical Outcomes of Intraabdominal versus Vaginal Approach for Uterine Manipulation during Total Laparoscopic Hysterectomy
Authors: GÜVEN Cenk Mustafa , UYSAL Dilek , KOLSUZ Zafer , YILMAZ Bülent 
Published: December 2022

Abstract

Background: Uterine manipulation is essential for moving the uterus and proper anatomical dissection without complications during total laparoscopic hysterectomy (TLH). Although many different uterine manipulators (UM) have been designed in the last few decades, there is still no ‘optimal UM’ that is universally safe, efficient, and cost-effective. This study aimed to compare myoma screw (MS) and UM with regard to surgical outcomes and cost-effectiveness in patients who underwent TLH.Methods: In the current study, we describe an operation technique that uses a MS instead of a uterine manipulator during TLH and discuss the surgical outcomes of this method.Results: The use of MS resulted in significantly shorter operation time with respect to UM for uterine manipulation during TLH regarding benign indications, with affordable costs.Conclusion: The use of MS is a safe and cost-effective alternative to the use of UM during TLH.
Reliability and Validity of the Traditional Chinese Version of the Wound Quality of Life
Authors: Wu Yu-Lin , Hsu Mei-Yu , Kuo Yu-Chen , Hsu Hsiao-Hui , Lin Jui-Ping , Huang Zih-Chun 
Published: December 2022

Abstract
Objective: Patients with chronic wounds experience substantial quality of life (QoL) impairments. The Wound–QoL is a simple, valid tool for the longitudinal assessment of QoL in patients with chronic wounds. In this study, the Wound–QoL was translated into traditional Chinese, and the validity of the translated version was investigated.
Methods: The Wound–QoLwas translated into traditional Chinese following international standards. In total, 100 patients with chronic wounds were enrolled. Participants completed 2 questionnaires 1 week apart. Data on demographics and the seriousness of wounds were collected. The EQ–5D–5L, the EQ VAS, and a subjective pain assessment instrument were also used.
Results: The mean global scores of the Wound–QoL–TC were 2.7 in the first test and 2.1 in the second test. The intraclass correlation coefficient between the first and second test was 0.70 for the global score. The Wound–QoL–TC showed good internal consistency, with a Cronbach’s α of 0.93 for the global score, 0.82 for the body subscale score, 0.89 for the psyche subscale score, and 0.88 for the everyday life subscale score. The global score of the Wound–QoL–TC was significantly correlated with the subjective pain score and the EQ–5D–5L total score (coefficient: 0.517, 0.386; both P < .001) but not with the EQ VAS (coefficient: −0.145; P = 0.234).
Conclusion: The Wound–QoL–TC is a valid and simple instrument for assessing QoL in patients with chronic wounds.
Quantum correlations in the frustrated XY model on the honeycomb lattice
Authors: Satoori Sahar , Mahdavifar Saeed , Vahedi Javad 
Published: December 2022

Abstract
We consider the spin-1/2 XY frustrated antiferromagnetic Heisenberg honeycomb model. There is an unclear intermediate region in the ground state phase diagram of the model. The most recognized phases are the quantum spin-liquid (QSL) and the antiferromagnetic Ising ordering. From the viewpoint of the quantum correlations, the QSL phase is expected to be entangled. Motivated by this fact, we have calculated the concurrence, the quantum discord (QD), and the entanglement entropy, by using numerical Lanczos and density matrix renormalization group (DMRG) methods. Our results explicitly show that the intermediate region should be entangled supporting the QSL phase.
Effect of Agricultural Land Management Practices on the Selected Soil Quality Indictors: Empirical Evidence from the South Ethiopian Highlands
Authors: Abera Aklilu , Wana Desalegn 
Published: December 2022

Abstract

Land degradation is a major challenge that adversely affects soil fertility, agricultural production, and food security. To curb this, different Agricultural land management (ALM) measures are being put into practice. The purpose of this study was to evaluate the effects of practices on soil quality indicators in Ojoje sub-watershed, Southern Ethiopia Highlands. Judgment sampling techniques were used to collect representative soil samples. Samples were collected at a depth of 0–20cm by using both an auger and a core sampler. A total of 72 composite soil samples were collected from non-treated and treated plots (i.e., land treated for five and ten years with only physical practices and integrated measures). Soil quality indicator tests were done through standard laboratory procedures. One way ANOVA was used to demonstrate statistically significant variation on soil quality indicators. Simple regression analysis was used to explain the proportional variance of soil quality indicators due to ALM measures. The results indicate that treatment types and duration of interventions of ALM practices have significant and positive effects on soil quality indicators (p < 0.05). The effect of ALM practices was stronger when land was treated with integrated Agricultural land management practices; irrespective of the duration of interventions. Hence, integrating ALM practices and maintaining them for the long-term is essential improve soil quality and enhance agricultural productivity in the study watershed.
Atmospheric Dust Intrusions From the Peninsular Region Into the Northern Gulf of California: Case Study
Authors: Morales-Acuña Enrique , Santamaría-del-Ángel Eduardo , Linero-Cueto Jean 
Published: December 2022

Abstract

Through atmospheric transport, coming from the mainland, an important amount of dust arrives to surface waters of open-ocean regions and many coastal zones. Semi-arid and desert areas tend to act as important sources of dust. The Gulf of California (GC) is one of the most productive marginal seas of the world, and it is surrounded by the semi-arid deserts located in Baja California Peninsula, United States, and Sonora (Mex). Dust fluxes coming from the BCP during the summer are relevant due biological impact on the California Gulf. In the northern region of the BCP, meteorological events have not been well studied. These events are known in popular slang as "El Torito". The characterization of a dust event that originated in the Baja California Peninsula (BCP) on June 14, 2016, is presented. Meteorological variables (from North American Regional Reanalysis -NARR), daily sea surface temperature, and aerosol optical thickness (from MODIS) to explain the dust event genesis, are used. Results suggest that sea surface temperature fluctuations in the Pacific Ocean off the coast of the BCP generate changes in hydrometeorological variables (wind, relative humidity, and atmospheric pressure) that can give rise to dust events. These atmospheric dust intrusions in the foothills of the San Felipe desert are originated. They are distributed from the source areas to the northern Gulf of California, as shown by aerosol optical thickness images and HYSPLIT trajectory simulations, which establish vertical distributions with predominant heights between 0 and 500 m during June 14.