bluuebunny/crossref_metadata_2025_split huggingface dataset:
Application of the multi-walled carbon nanotube and sodium alginate based sol-gel coatings to enhance the electrically actuated performance of muscle-like biomass hydrogel paper actuators
Authors: Yang Junjie , Yu Tao , Yao Jintong , Wang Siyong , Wei Kang 
Published: July 2022

Abstract
To comply with green chemistry and achieve sustainable development, an electrically actuated membrane and two non-metallic electrode membranes are assembled into a muscle-like Biomass Hydrogel Paper Actuator (BHPA) similar to ‘sandwich’ structure, which has a great potential in engineering application due to the excellent properties such as light weight, low driving voltage and good flexibility. And the contact resistance between every two membranes of the BHPA is the key factor to improve its output force characteristics and tremor behavior. Thus, in this paper, based on the orthogonal experiment and control variates, under the excitation of electric field, the effect and mechanism of Multi-walled Carbon Nanotube (MWCNT) - Sodium Alginate (SA) based sol-gel coating and its thickness on electrically actuated performances of the BHPA were studied in depth and the results were compared with that of the BHPA samples assembled by the traditional hot laminating technology. Furthermore, with equivalent circuit model, the preliminary quantitative relationship between peak current and contact resistance of the BHPA was derived by a mathematical expression. The results demonstrated that the optimum dimension and testing voltage of the BHPA were 35 mm × 8 mm × 1 layer (0.352 mm) and 4 V, where its output force density and service life both reached the maximum values of 13.34 mN/g and 330 s with the lightest tremor behavior. Moreover, the internal resistance and elastic modulus of the BHPA achieved the minimum values of 2.13 Ω and 3.1 MPa respectively, and its specific capacitance acquired the maximum value of 81.3 mF/g under the sol-gel coating of 1 coating thickness. Generally, it is of great value to modify interface properties of the BHPA for actuation enhancement in demanding working conditions.
Association of PTPRC Exon 4 and 6 Gene Polymorphisms in Idiopathic Recurrent Pregnancy Loss: A Couple -Based Study from South India.
Authors: Avvari Srilekha , Kavutharapu Sri Manjari , Galimudi Rajesh Kumar , Ananthapur Venkateshwari , Akka Jyothy 
Published: July 2022

Abstract
Purpose
Recurrent pregnancy loss (RPL) implies to two or more consecutive pregnancy losses before 20 weeks of gestation with the same partner. Numerous studies have investigated the role of biochemical parameters with respect to PTPRC (Protein Tyrosine Phosphatase Receptor C) in embryonic development and pregnancy success. However, the PTPRC genetic polymorphisms in RPL have not been reported in the literature.
Methods:
Our study included one hundred and twenty-five couples with a history of RPL and 125 healthy couples who had one or more successful pregnancies without history of miscarriages as controls. Peripheral blood was used to isolate the DNA, which was followed by genotyping of PTPRC gene, C77G and A138G polymorphisms, by Allele specific PCR method.
Results:
The results showed significant association of PTPRC, rs17612648 and rs4915154 in both the partners of RPL cases when compared to controls. It is observed that the CG genotype of rs17612648 was predominant in couples with RPL. With regard to PTPRC rs4915154 polymorphism, only AG genotype was significant in RPL females when compared to control females. However, males with history of RPL showed a greater risk for both AG and GG genotypes. Haplotype analysis revealed the presence of minor allele in both the exons 4 and 6 increases the risk for RPL.
Conclusion:
In summary, our pilot study in south Indian population revealed significant association of PTPRC gene polymorphisms C77G and A138G in couples with RPL. Further studies in other populations on functional and disease associations are warranted.
A New Missense Mutation in DPM2 Gene is Associated with a Milder Form of DPM2-CDG in Two Chinese Siblings
Authors: Zhao Peiwei , Hu Yanqiu , Hu Juan , Huang Yufeng , Zhang Lei , Luo Sukun , Xiong Ping , Zhu Hongmin , He Xuelian 
Published: July 2022

Abstract
Background
Congenital disorders of glycosylation (CDGs) are a genetically heterogeneous group of metabolic disorders caused by abnormal protein or lpid glycoproteins. DPM2 is a subunit of a heterotrimeric complex (dolichol-phosphate-mannose synthase, DPMS), a key enzyme in glycosylation, and only four patients with DPM2-CDG have been reported.
Methods
Whole exome sequencing (WES) was applied to analyze a Chinese family with two daughters with developmental delay, milder intellectual disability, hypotonia and increased serum creatine kinase. In vitro functional study was performed to evaluate the impact of pathogenic genetic mutation .
Results
A homozygous mutation, c.197G > A (p.G66E) in exon 4 of DPM2 gene (NM_003863) was identified by whole exome sequencing. In vitro functional analysis demonstrated that this variant increased the expression level of DPM2 protein and western blot revealed a significant decrease in ICAM1, a universal biomarker for hypoglycosylation in patients with CDG, suggesting abnormal N-linked glycosylation. We also review the 4 previously reported patients carried homozygous or compound heterozygous mutations of DMP2 gene, and found that mutations within the region encoding the first domain is correlated with more severe clinical symptoms than ones within the second domain, establishing the possible correlation of genotypes and phenotype based on the localization of the variants.
Conclusions
our study broadens the mutation spectrum of DPM2 genes, expands the genetic and phenotypic relevance of DPM2 variants, and emphasizes the need of further functional studies to understand the underlying pathophysiology of the phenotype heterogeneity.
Research trends and Hotspots of Thrombophilia with recurrent pregnancy loss: a Bibliometric Analysis
Authors: Deng Ying-jun , Liu Sheng-Jing , Zhao Ming , Zhao Feng , Guo Jun , Huang Yu-xiao 
Published: July 2022

Abstract
Background: Thrombophilia is a group of disorders that result in a blood hypercoagulable state and induce thrombosis, which was found widely existed in recurrent pregnancy loss (RPL). More and more research about thrombophilia has been conducted but the association between thrombophilia and RPL remains uncertain. Thus, it’s necessary to combine relevant literature to find the research hotspots and analyze the internal link between different study points, and then predict the development trend in RPL with thrombophilia.Methods: Relevant articles between 1990 and 2022 were obtained from the Web of Science (WoS) database. Software VOSviewer and CiteSpace were used to perform the analysis and conduct visualization of scientific productivity and emerging trends.Results: 742 articles published in recent 30 years by 3205 authors from 1139 organizations and 68 countries were analyzed. 37authors, 38 countries, and 53 organizations published papers ≥5. The USA was the most productive country and Univ Amsterdam was the most productive institution. Journal thrombosis and haemostasis had the most total citations. In keyword and clusters, factor-v-Leiden, inherited thrombophilia, activated protein-c, low-dose aspirin, molecular-weigh heparin, polymorphism had high-frequency focus on its etiology, diagnostics, and therapeutics. The strongest keyword bursts showed the research hotspots changed over time.Conclusions: By Bibliometric Analysis, we comprehensively reviewed publications related to thrombophilia and RPL during the past 30 years. The research in the relationship between thrombophilia and RPL suggested that there could be differences in the clinical relevance of the different types of thrombophilia. And we should attach more attention to this relationship in in-vitro fertilization.
Afebrile chemotherapy-induced neutropenia: international survey of oncologists’ perspectives against the standard of care in the COVID-19 era
Authors: Saad Ereny Samwel Poles , Qualla Karima , Talibova Narmin , Gening Snezhanna , Yousef Shady Yousef Gayed 
Published: July 2022

Abstract
Introduction:Afebrile chemotherapy-induced neutropenia represents a frequent clinical situation where chemotherapy protocol, patient’s comorbidities, and disease status determine the risk of infection hence the management plan. Internationally distributed, this questionnaire aims to evaluate the routine practice and the impact of the COVID 19 pandemic on afebrile chemotherapy-induced neutropenia management. Material and Methods:Coordinators from Egypt, Morocco, Azerbaijan, and Russia developed a 12-item questionnaire using Google forms to explore how oncologists deal with afebrile chemotherapy-induced neutropenia. The link to the survey was available internationally through social media and to their local societies over the period from July to September 2021.Results:We received 151 responses from 4 world regions: 58.9, 9.9, 11.3, and 15.2% from the Mena area, Russia, Europe, and Asia. The responses deviated from the guideline-driven practice as G-CSF was the most chosen option for intermediate-risk that was statistically different based on the academic background of the treating physician. Half of the responders ignored patients and disease risk factors in the intermediate-risk cases that trend was statistically different based on the geographical distribution. The steroid was a valid option for intermediate and low-risk as per oncologists practicing in Russia. COVID-19 pandemic positively affected the rate of prescription of G-CSF as expected.Conclusion:The disparities in the routine practice of oncologists based on their geographical and academic backgrounds highlight the need to analyze the underlying obstacles that hinder guidelines-based practice like workload or lack of the proper knowledge.
Successful Experiments in Blending Rubber(s) with Polyester Waste Fabric to Produce Products of Industrial and Domestic Use
Authors: Padhiyar Bhavesh , Wagh Shrikant J. 
Published: July 2022

Abstract
Non-woven polyester fabric waste is available in huge quantities from industry which is difficult to reuse. It cannot be melted nor can it be dissolved in any solvent owing to its complex structure and cross-linking. Presently it is incinerated or burned in cement industry. But its burning creates hazardous pollutants. This study focuses on utilizing the strength and durability of the two raw materials involved to form a Polyester Rubber Composite (PRC) with improved stability and process ability. A detailed chemical and mechanical analysis of PRC has been done, which indicates compatibility of the two polymers and enhancement in the hardness of the rubber by around 20–45 units. The PRC has been subjected to compression molding to fabricate commercial products like Bush and gaskets, which exhibit significant enhancement in chemical, processing and physical properties. A brief economic analysis of PRC gasket and virgin butyl rubber gasket shows a reduced cost margin of approx. 7.00% in the processing cost of the former, validating the market potential of the product. The utilization of these industrial waste materials, whose current disposal practices pose a concern at environmental level, into serviceable products gives a route for sustainable recycling practices.
Highly effectual photocatalytic degradation of tartrazine by using Ag nanoparticles decorated on Zn-Cu-Cr layered double hydroxide@ 2D graphitic carbon nitride (C3N5)
Authors: Akbarzadeh Abbas , Khazani Yeganeh , Khaloo Shokooh , Ghalkhani Masoumeh 
Published: July 2022

Abstract
Pollution of water resources is one of the main concerns of many countries. This issue originates from the entry of diverse pollutants, including dye compounds, into water sources. In this work, ternary Zn-Cu-Cr layered double hydroxides (LDH) supported on graphitic carbon nitride (g-C3N5) decorated by silver nanoparticles (C3N5-LDH-Ag) was first prepared. Application of various characterization techniques such as SEM, XRD, and FT-IR revealed that the synthesized nanocomposite was composed of Zn-Cu-Cr LDH nanoparticles, g-C3N4 nanosheets, and Ag nanoparticles. The prepared nanomaterials were employed for the photodegradation of tartrazine in aqueous solutions. It was found that the C3N5-LDH-Ag catalyst outperformed their pure g-C3N5, Zn-Cu-Cr LDH, and C3N5-LDH composite in photocatalytic degradation of tartrazine under visible light irradiation. Tartrazine (20 mg/L) can be entirely removed by 0.25 g/L C3N5-LDH-Ag photocatalyst under one h visible light irradiation (200W) at pH 6 with a rapid degradation rate constant (k) that is 4.4, 3.9, and 2.6 times higher than that of pure C3N5, Zn-Cu-Cr LDH, and C3N5-LDH component, respectively. The formation of hydroxyl radicals on the surface of C3N5-LDH-Ag as the main active species was approved by the capturing experiment. The finding results approved the stability and reusability of C3N5-LDH-Ag in four photocatalytic degradation cycles. In general, our findings revealed that the synthesized nanocomposite could be employed as an efficient photocatalyst in environmental remediation.
Semi-supervised underwater acoustic source localization based on residual convolutional autoencoder
Authors: Pian Jin , Biao Wang , Bo Li Le , Peng Chao , Tong Xie Fang 
Published: July 2022

Abstract
Passive localization of underwater targets was a thorny problem in underwater acoustics. For traditional model-driven passive localization methods, the main challenges are the inevitable environmental mismatch and the presence of interference and noise everywhere. In recent years, data-driven machine learning approaches have opened up new possibilities for passive localization of underwater acoustics. However, the acquisition and processing of underwater acoustics data are more restricted than other scenarios, and the lack of data is one of the most enormous difficulties in the application of machine learning to underwater acoustics. To take full advantage of the relatively easy accessed unlabeled data, this paper proposes a framework for underwater acoustic source localization based on a two-step semi-supervised learning classification model. The first step is trained in unsupervised mode with the whole available dataset (labeled and unlabeled dataset), it consists of a convolutional autoencoder (CAE) for feature extraction and self-attention (RA) mechanism for picking more useful features by applying constraints on the CAE. The second step is trained in supervised mode with the labeled dataset, it consists of a multilayer perceptron (MLP) connected to an encoder from the first step and is used to perform the source location task. The proposed framework is validated on uniform vertical line array (VLA) data of SWellEx-96 event S5. Compared with the supervised model and the model without the RA, the proposed framework maintains good localization performance with the reduced labeled dataset, and the proposed framework is more robust when the training dataset and the test dataset of the second step are distributed differently, which is called “data mismatch”.
RegentK regenerative treatment available for ruptured anterior cruciate ligament? A scoping review
Authors: Tedeschi Roberto 
Published: July 2022

Abstract
BackgroundConservative/regenerative therapy for cruciate ligament ruptures can be considered as primary treatment. However, nowadays, the first option is almost always only surgical, although studies on the efficacy of intervention exist in the literature.AimThis scoping review aimed to map and summarise the literature to identify interventions with Regentk therapy available for cruciate ligament ruptures.MethodsFour databases were searched until May 2022. Studies that considered anterior cruciate ruptures treated with the Regentk method could be included. All interventions and contexts were considered. No restrictions were applied regarding language, study design and publication type. No grey literature and reference lists of included articles were identified. Results were presented in numerical and thematic form.ResultsFrom 245 initial records, 7 studies met the inclusion criteria. Most of the articles were RCTs and considered sports patients with cruciate ligament ruptures. The authors discussed only one range of interventions: conservative (n = 7). Specifically, the conservative/regenerative Regentk treatment.ConclusionsThis is the first scoping review that provides a comprehensive overview of the topic. The results revealed clear gaps in primary research, confirming that current management is based on surgery. This review may be useful for overall management and may provide a starting point for future research.
A case study on the importance of secondary structural components in the seismic resilience of major bridges
Authors: Yazdani Ahmad , Bocchini Paolo , Dehkordi Morteza Raissi , Eghbali Mahdi , Samadian Delbaz 
Published: July 2022

Abstract
Any reduction in the performance of bridges, as one of the important components of transportation facilities, might lead to significant direct and indirect economic losses and casualties to communities, which should not be underestimated. This paper presents a case study on a major bridge in the metropolis city of Tehran, Iran, and adopts a comprehensive probabilistic approach for the assessment of fragility, recovery, and resilience of the bridge. One of the results of the case study is a set of fragility curves for this landmark bridge. More importantly, the study focuses on the significance of modelling secondary structural components for an accurate assessment of the system failure and, in turn, system resilience. The results show that the influence of secondary components on the resilience index and vulnerability of bridges under more severe events can be ignored; however, for events corresponding to lower hazard levels their impacts on resilience should not be overlooked. Also, the results reveal that the HAZUS fragility parameters for the major bridge classes would result in an inaccurate seismic resilience index, compared to that resulting from a comprehensive analysis. This framework would help policy makers and stakeholders to have reliable information to support their decisions to create safe and resilient transportation facilities for citizens.
Associations between competitive goals in sports and body size perception among Finnish adolescents: a cross-sectional study
Authors: Mäkituomas Leevi , Heikkilä Laura , Nurkkala Marjukka , Korpelainen Raija , Alanko Lauri , Heinonen Olli Juhani , Kokko Sami , Kujala Urho , Parkkari Jari , Savonen Kai , Valtonen Maarit , Vasankari Tommi , Villberg Jari , Vanhala Marja 
Published: July 2022

Abstract
Background: Regardless of competitive athletes’ body image pressures, the role of competitive goals in sports on adolescents’ body perception has not been studied. We examined the factors associated with adolescents’ competitive goals in sports and body size perception, and the associations between adolescents’ competitive goals in sports and body size perception.Methods: The cross-sectional study included 475 goal-oriented sports club participants and 936 reference youths (aged 14–16 years) with self-reported data on health behaviours and accelerometer-measured physical activity. The multinomial logistic regression analysis was used to investigate the associations.Results: Adolescents with competitive goals in sports were more frequently satisfied with their body size than reference youths (68% vs 47%, p < 0.001 in girls; 74% vs 61%, p < 0.001 in boys). More than one-fourth of girls with competitive goals in sports perceived themselves as overweight, although only 7% of them were overweight. Adolescents with appearance/weight motives to exercise and poor perceived physical fitness had higher odds of perceived fatness. Additionally, BMI was positively associated with perceived fatness and negatively with perceived thinness. Having competitive goals in sports was not independently associated with perceived fatness or perceived thinness.Conclusions: Adolescents’ BMI, appearance/weight motives to exercise, and perceived physical fitness were more strongly associated with body size perception than their competitive goals in sports. However, body size dissatisfaction among girls with competitive goals in sports should be considered in organized sports.
A revised work on the Rayleigh-Bénard instability of nanofluid in a porous medium layer
Authors: Chang Min-Hsing , Yan Wei-Mon , Ruo An-Cheng 
Published: July 2022

Abstract
Instability of a horizontal porous medium layer saturated by a nanofluid heated from below is revisited. The study employs Buongiorno’s model for nanofluids and Darcy model for porous media. Different from the previous studies, this analysis is performed based on a nonlinear base-state solution, obtained by considering the dependence of thermophoretic diffusion coefficient on the volume fraction of nanoparticles. It is found that an infinitesimal temperature gradient is sufficient to overcome Darcy drag and trigger the onset of convection in a porous layer. In comparison with the previous works, the threshold of instability in presence of the nonlinear particle distribution shifts to lower concentration by two orders of magnitude. The physical mechanism causing the enhancement of instability is explained via an order of magnitude analysis. The theoretical result suggests that the instability in a porous media can be enhanced substantially by suspending nanoparticles.
Uplifted structures due to the obliquely subducted Gagua Ridge below the Nanao Basin imaged from MCS/OBS data
Authors: Deng Jia-Ming , Wang Tan K. , Wege Sebastian , Hu Wan Ting , Deng Yi Jie 
Published: July 2022

Abstract
At the southernmost part of the Ryukyu subduction zone, data recorded by 28 ocean-bottom seismometers with active sources during the TAiwan Integrated GEodynamics Research (TAIGER) experiment in 2009 were re-analyzed. Additionally, six long-offset multi-channel seismic profiles across three forearc basins and the Yaeyama accretionary prism north of the southernmost Ryukyu Trench, obtained by the TAIGER experiment in 2009 and the TAICRUST project in 1995, were processed to generate pre-stack depth migration (PSDM) sections. Due to the NW convergence of the Philippine Sea Plate (PSP), the Gagua Ridge may have been obliquely subducting northwestward beneath the Yaeyama accretionary prism and below the Nanao Basin. The PSDM sections and the velocity-interface models show that the Yaeyama accretionary prism near the trench, the sedimentary basement and the lower crustal structure below the Nanao Basin were uplifted by the tip of the subducted Guagua Ridge. Furthermore, the sedimentary and crustal structures near ~ 122.5°E beneath the Nanao Basin were shown a north-trending uplift where shallow earthquakes had been occurred by the oblique subduction of the Gagua Ridge depicted in the isopach map of the crust. Moreover, a recent earthquake (Mw ~ 6.0) near the NE coast of Taiwan in 2018 at a depth of approximately 12 km below the Hsincheng Ridge was caused due to a thrust fault near the décollement that might have been formed by subduction of the PSP.