bluuebunny/crossref_metadata_2025_split huggingface dataset:
An equivalent source method for removal of attitude-induced responses in drone-towed magnetic scalar gradiometry data
Authors: Petersen Jacob Thejll , Kolster Mick E , Rasmussen Thorkild M , Døssing Arne 
Published: October 2022

SUMMARY
Drone-towed scalar field gradiometry surveys conducted in windy conditions or under self-excited oscillations generate attitude-induced responses that can hinder the geological interpretation. Here, we present a gradiometric equivalent source method (GESM) to remove these attitude-induced responses by interpolating and continuing the measured gradiometry data to new idealized pseudo-sensor positions free of any attitude deviations. In addition, we present transverse horizontal difference (THD) data from a precisely positioned drone-towed horizontal gradiometry survey collected in Nautanen, northern Sweden. Analysing the Nautanen survey’s positional data revealed that the gradiometer system exhibited directional-dependent yaw deviations with periods of unpredictable attitude deviations. Based on synthetic THD data created using the Nautanen survey’s positional data, these deviations manifest as line-to-line striping and short-wavelength oscillations in the THD maps. Applying GESM to the synthetic THD data removes these attitude-induced THD responses with satisfactory accuracy compared to the true THD values. Furthermore, on the actual THD data collected in Nautanen, applying GESM improved the continuity of anomalies, significantly improving the interpretation of the data. The results suggest that including GESM in the data processing of drone-towed gradiometry surveys, given precise positional information via an onboard GNSS-IMU system, ensures high-quality geological interpretation even in windy conditions or in high-gradient areas.
The essential role of jasmonate signaling in Solanum habrochaites rootstock-mediated cold tolerance in tomato grafts
Authors: Wang Lihui , Wu Bo , Chen Guoyu , Chen Hui , Peng Yuquan , Sohail Hamza , Geng Shouyu , Luo Guangbao , Xu Dandi , Ouyang Bo , Bie Zhilong 
Published: October 2022

Abstract
Tomato (Solanum lycopersicum) is among the most important vegetables across the world, but cold stress usually affects its yield and quality. The wild tomato species Solanum habrochaites is commonly utilized as rootstock for enhancing resistance against abiotic stresses in cultivated tomato, especially cold resistance. However, the underlying molecular mechanism remains unclear. In this research, we confirmed that S. habrochaites rootstock can improve the cold tolerance of cultivated tomato scions, as revealed by growth, physiological, and biochemical indicators. Furthermore, transcriptome profiling indicated significant differences in the scion of homo- and heterografted seedlings, including substantial changes in jasmonic acid (JA) biosynthesis and signaling, which were validated by RT–qPCR analysis. S. habrochaites plants had a high basal level of jasmonate, and cold stress caused a greater amount of active JA-isoleucine in S. habrochaites heterografts. Moreover, exogenous JA enhanced while JA inhibitor decreased the cold tolerance of tomato grafts. The JA biosynthesis-defective mutant spr8 also showed increased sensitivity to cold stress. All of these results demonstrated the significance of JA in the cold tolerance of grafted tomato seedlings with S. habrochaites rootstock, suggesting a future direction for the characterization of the natural variation involved in S. habrochaites rootstock-mediated cold tolerance.
Designing in Pandemic Context: Scientific Collaboration through the OpenDesign Platform
Authors: Gonçalves Fabrício Matheus , Baranauskas M Cecília C 
Published: October 2022

AbstractThe Coronavirus pandemic and the consequent situation of social isolation have affected research design, especially in fields working directly with people. While online tools enable communication and collaboration, some specific domains involving contemporary technology-based systems, such as socioenactive systems, demand a deeper understanding of human-embodied action in real-world scenarios with ubiquitous technology. This work addresses this issue by presenting a study in which a research team used the OpenDesign Platform (ODP) to conduct a process of ideation and consolidation of a socioenactive-based system solution during pandemics and physical presence limitations. The contributions are twofold: addressing the demands of the research team working remotely and envisaging an interaction scenario for people in a socioenactive system, even without their copresence in the same physical space. Results have shown the strengths and weaknesses of the ODP and lessons learned towards supporting systems for teamwork in such systems’ ideation context.
Timing and spectral studies of Cen X-3 in multiple luminosity states using AstroSat
Authors: Bachhar Ritesh , Raman Gayathri , Bhalerao Varun , Bhattacharya Dipankar 
Published: October 2022

ABSTRACT
We present the results of timing and spectral analysis of the high-mass X-ray binary pulsar, Cen X-3, with the help of observations carried out using the Large Area X-ray Proportional Counter onboard AstroSat. As part of our analysis, we sampled the source properties during four different observation epochs covering two widely different intensity states. We obtain a timing solution and report precise measurements of the spin and orbital parameters corresponding to these observational epochs. The pulse profiles during the two intensity states reveal dramatically varying shapes within a time span of 1 month. We report the detection of one of the lowest measured frequencies of quasi-periodic oscillations at 0.026 ± 0.001 Hz for Cen X-3 during its low-intensity state. We also find correlated periodic and aperiodic noise components in the power density spectra. We further carried out a phase-averaged and a pulse phase-resolved spectral study, where we find that the best-fitting continuum spectrum is well described by an absorbed Comptonization model along with a blackbody. Cen X-3 exhibited the presence of the ∼28 keV cyclotron resonant scattering feature absorption line and a ∼6.6 keV Fe emission line in both the intensity states. Significant variations in the line-forming regions and mode of accretion for Cen X-3 within time spans of a month make Cen X-3 a highly dynamic persistent binary.
New ASKAP radio supernova remnants and candidates in the Large Magellanic Cloud
Authors: Bozzetto Luke M , Filipović Miroslav D , Sano H , Alsaberi R Z E , Barnes L A , Bojičić I S , Brose R , Chomiuk L , Crawford E J , Dai S , Ghavam M , Haberl F , Hill T , Hopkins A M , Ingallinera A , Jarrett T , Kavanagh P J , Koribalski B S , Kothes R , Leahy D , Lenc E , Leonidaki I , Maggi P , Maitra C , Matthew C , Payne J L , Pennock C M , Points S , Reid W , Riggi S , Rowell G , Sasaki M , Safi-Harb S , van Loon J Th , Tothill N F H , Urošević D , Zangrandi F 
Published: October 2022

ABSTRACT
We present a new Australian Square Kilometre Array Pathfinder (ASKAP) sample of 14 radio supernova remnants (SNR) candidates in the Large Magellanic Cloud (LMC). This new sample is a significant increase to the known number of older, larger, and low surface brightness LMC SNRs. We employ a multifrequency search for each object and found possible traces of optical and occasionally X-ray emission in several of these 14 SNR candidates. One of these 14 SNR candidates (MCSNR J0522 – 6543) has multifrequency properties that strongly indicate a bona fide SNR. We also investigate a sample of 20 previously suggested LMC SNR candidates and confirm the SNR nature of MCSNR J0506 – 6815. We detect lower surface brightness SNR candidates which were likely formed by a combination of shock waves and strong stellar winds from massive progenitors (and possibly surrounding OB stars). Some of our new SNR candidates are also found in lower density environments in which SNe type Ia explode inside a previously excavated interstellar medium.
The nova KT Eri Is a recurrent nova with a recurrence time-scale of 40–50 yr
Authors: Schaefer Bradley E , Walter Frederick M , Hounsell Rebekah , Hillman Yael 
Published: October 2022

ABSTRACT
KT Eridani was a very fast nova in 2009 peaking at V = 5.42 mag. We marshal large data sets of photometry to finally work out the nature of KT Eri. From the TESS light curve, as confirmed with our radial velocity curve, we find an orbital period of 2.61595 d. With our 272 spectral energy distributions from simultaneous BVRIJHK measures, the companion star has a temperature of 6200 ± 500 K. Our century-long average in quiescence has V = 14.5. With the Gaia distance (5110$^{+920}_{-430}$ pc), the absolute magnitude is $M_{V_q}$ = +0.7 ± 0.3. We converted this absolute magnitude (corrected to the disc light alone) to accretion rates, $\dot{M}$, with a full integration of the α-disc model. This $\dot{M}$ is very high at 3.5 × 10−7 M⊙ yr−1. Our search and analysis of archival photographs shows that no eruption occurred from 1928 to 1954 or after 1969. With our analysis of the optical light curve, the X-ray light curve, and the radial velocity curve, we derive a white dwarf mass of 1.25 ± 0.03 M⊙. With the high white dwarf mass and very-high $\dot{M}$, KT Eri must require a short time to accumulate the required mass to trigger the next nova event. Our detailed calculations give a recurrence time-scale of 12 yr with a total range of 5–50 yr. When combined with the archival constraints, we conclude that the recurrence time-scale must be between 40 and 50 yr. So, KT Eri is certainly a recurrent nova, with the prior eruption remaining undiscovered in a solar gap of coverage from 1959 to 1969.
Evolutionary Responses of a Reef-building Coral to Climate Change at the End of the Last Glacial Maximum
Authors: Zhang Jia , Richards Zoe T , Adam Arne A S , Chan Cheong Xin , Shinzato Chuya , Gilmour James , Thomas Luke , Strugnell Jan M , Miller David J , Cooke Ira 
Published: October 2022

AbstractClimate change threatens the survival of coral reefs on a global scale, primarily through mass bleaching and mortality as a result of marine heatwaves. While these short-term effects are clear, predicting the fate of coral reefs over the coming century is a major challenge. One way to understand the longer-term effect of rapid climate change is to examine the response of coral populations to past climate shifts. Coastal and shallow-water marine ecosystems such as coral reefs have been reshaped many times by sea-level changes during the Pleistocene, yet few studies have directly linked this with its consequences on population demographics, dispersal, and adaptation. Here we use powerful analytical techniques, afforded by haplotype-phased whole-genomes, to establish such links for the reef-building coral, Acropora digitifera. We show that three genetically distinct populations are present in northwestern Australia, and that their rapid divergence since the last glacial maximum (LGM) can be explained by a combination of founder-effects and restricted gene flow. Signatures of selective sweeps, too strong to be explained by demographic history, are present in all three populations and overlap with genes that show different patterns of functional enrichment between inshore and offshore habitats. In contrast to rapid divergence in the host, we find that photosymbiont communities are largely undifferentiated between corals from all three locations, spanning almost 1000 km, indicating that selection on host genes, and not acquisition of novel symbionts, has been the primary driver of adaptation for this species in northwestern Australia.
Prevalence of Intestinal Helminth Coinfection in Drug-Resistant Tuberculosis in Uganda
Authors: Baluku Joseph Baruch , Nakazibwe Bridget , Wasswa Amir , Naloka Joshua , Ntambi Samuel , Waiswa Damalie , Okwir Mark , Nabwana Martin , Bongomin Felix , Katuramu Richard , Nuwagira Edwin , Ntabadde Kauthrah , Katongole Paul , Senyimba Catherine , Andia-Biraro Irene 
Published: October 2022

Abstract

Background
Although a third of people with tuberculosis (TB) are estimated to be coinfected with helminths, the prevalence is largely unknown among people with drug-resistant TB (DR-TB). We determined the prevalence of helminth coinfection among people with DR-TB in Uganda.

Methods
In a multicenter, cross-sectional study, eligible Ugandan adults with confirmed DR-TB were consecutively enrolled between July to December 2021 at 4 treatment centers. Sociodemographic data were collected using a questionnaire. Participants underwent anthropometric and blood pressure measurements, and blood samples were evaluated for random blood glucose, glycated hemoglobin, nonfasting lipid profile, human immunodeficiency virus (HIV) infection, and a complete blood count. Fresh stool samples were evaluated for adult worms, eggs, and larvae using direct microscopy after Kato-Katz concentration techniques.

Results
Of 212 participants, 156 (73.6%) were male, 118 (55.7%) had HIV, and 3 (2.8%) had malaria coinfection. The prevalence of intestinal helminth coinfection was 4.7% (10/212) (95% confidence interval, 2.6%–8.6%). The frequency of helminth infections was Ancylostoma duodenale (n = 4), Schistosoma mansoni (n = 2), Enterobius vermicularis (n = 2), Ascaris lumbricoides (n = 1), and Trichuris trichiura (n = 1).

Conclusions
The prevalence of helminth coinfection was low among people with DR-TB. More studies are needed to determine the clinical relevance of helminth/DR-TB coinfection.
Being Cared for in the Context of Crisis: Austerity, COVID-19, and Racialized Politics
Authors: Akhter Shahnaz , Elias Juanita , Rai Shirin M 
Published: October 2022

Abstract
This article presents an investigation into the racialized and gendered dynamics of the intensifying crisis in care for older people in the United Kingdom. Deploying a feminist political economy framework, we reveal how the care crisis is an intersectional crisis of social reproduction worsened by both austerity and COVID-19. We do this through an analysis of a small set of interviews with South Asian older women with care needs, conducted during the first period of UK national lockdown in 2020. This was a pilot study, focusing on the challenges faced in accessing formal and informal care during this period of the pandemic. The experiences, fears, and vulnerabilities that came through in the interviews are located within a broader analysis of the racialized care crisis—one that reveals the long-term harms that austerity, including “austerity Islamophobia,” generated for these older women and their families as they struggled to provide and access un/paid care.
Optimization of assisted reproductive technology outcomes in patients with polycystic ovarian syndrome: updates and unanswered questions
Authors: Fitz Victoria W. , Mahalingaiah Shruthi 
Published: October 2022

Purpose of review
Narrative review of recent literature on optimization of assisted reproduction technology outcomes in patients with polycystic ovarian syndrome (PCOS).

Recent findings
The key areas of focus include pre cycle treatment with the goal of cohort synchronization, methods of ovulation suppression and trigger medication. There is no definitive evidence that precycle treatment with combined oral contraceptives (COCs) or progestins improve or negatively impact in vitro fertilization outcomes in patients with PCOS. The reviewed evidence supports consideration of progestins as suppression of premature ovulation in patients with PCOS as an alternative to gonadotropin releasing hormone (GnRH) antagonist if a freeze all protocol is planned. There is limited prospective evidence in PCOS populations regarding use of a dual trigger using GnRH agonist and human chorionic gonadotropin (hCG).

Summary
This review has implications for clinical practice regarding ovarian stimulation protocols for patients with PCOS. We also identified areas of research need including the further exploration of the value of pre cycle COC or progestin use in a PCOS population, also the use of GnRH agonist in combination with hCG in a well defined PCOS population and using GnRH agonist trigger alone as a control.
Influenza Vaccination Receipt in Pediatric Patients With Cancer or Sickle Cell Disease
Authors: Yarnall J. Nathan , Mertens Ann , Yee Marianne , Orenstein Evan , Lai Kristina W. , Wasilewski-Masker Karen 
Published: October 2022

Background:
Influenza causes greater morbidity in children with cancer or sickle cell disease (SCD). Literature on influenza vaccination receipt for these populations is limited in low-vaccination states. Outpatient interventions improve vaccine receipt but isolated inpatient interventions remain unstudied.

Procedure:
We reviewed influenza vaccine receipt of children with cancer or SCD treated at Children’s Healthcare of Atlanta during three influenza seasons. We implemented a clinical decision support intervention during an influenza season and compared influenza vaccine receipt preintervention and postintervention among admitted children.

Results:
The oncology cohort (N=1548, 60% to 62%) and the SCD cohort (N=2549, 61% to 65%) had similar-to-higher vaccination receipt to the United States (58% to 64%, P=0.01 to 0.79) and Georgia (51% to 56%, P<0.01). The intervention did not significantly improve vaccination receipt for admitted children with cancer (40% vs. 56%, P=0.05 to 0.88) or SCD (44% vs. 56%, P=0.01). Regression modeling also found no significant increase in vaccine receipt (hematologic malignancy: 0.8 [0.73 to 0.98], solid tumor: 0.9 [0.80 to 1.90], central nervous system tumor: 0.9 [0.71 to 1.14], SCD: 0.9 [0.85 to 0.99]).

Conclusions:
Children with cancer and SCD have similar-to-greater influenza vaccination receipt compared with Georgia and the United States. An inpatient intervention did not significantly improve influenza vaccine receipt in these patient cohorts. Future studies are needed to identify alternative approaches to improving vaccine receipt in these cohorts.
Characterization of Airflow Parameters in the Olfactory Fissure Zone Based on Fluid Mechanics Method
Authors: Jian Feitong , Xie Dielai , Wu Shuo 
Published: October 2022

Objective:
Airflow in the olfactory fissure region is a necessary condition for olfaction. However, due to the complex anatomy of the olfactory fissure, it is difficult to characterize the airflow in this region. At present, there are few studies on the airflow characteristics of the olfactory fissure. The aim of this study is to investigate the characteristics of objective indicators of airflow parameters in the olfactory fissure region, such as flow velocity, flow rate, pressure and flow ratio, from the perspective of biofluid mechanics.

Methods:
In this study, the anatomical structure of the olfactory fissure zone was reconstructed in three dimensions using raw data from 32 healthy adults and 64 sinus computed tomography scans. To study the characteristics of airflow parameter variations in the olfactory fissure region in healthy adults, 10 cross-sectional sections were established in the olfactory fissure region using computational fluid dynamics after obtaining the airflow parameter values at different anatomical positions in the olfactory fissure region.

Results:
The average flow rate of the ten cross-sections in the olfactory fissure zone was 19.22±9.74 mL/s, the average flow velocity was 0.51±0.21 m/s, the average flow percentage was 5.45%±2.52%, and the average pressure was −13.35±6.74 Pa. The percentile method was used to determine the range of reference values for P90: average flow rate of 0.02–35.87 mL/s, average flow velocity of 0.24–0.94 m/s, average flow percentage of 1.57%–9.93%, and average pressure of −30.4–4.42 Pa. Among the ten cross-sectional systems of the olfactory fissure, the median of Plane3N-Plane8N is more stable and representative. In the olfactory fissure system, the corresponding anatomical position of Plane3N-Plane8N was in the posterior region of the olfactory fissure, mainly at the junction of the anterior, middle 1/3 to the posterior middle turbinate, which was consistent with the main distribution area of the olfactory mucosa.

Conclusion:
This study shows that the application of computational fluid dynamic can rapidly achieve the characterization of airflow parameters in the olfactory fissure. The airflow through the olfactory fissure in healthy adults accounted for no more than 10% of the total flow volume of the nasal cavity. The airflow parameters in the anterior region of the olfactory fissure fluctuated significantly, while those flowing through the posterior region of the olfactory fissure were more stable. This could be due to the anterior section of the middle turbinate truncating the restriction of airflow into the olfactory fissure.
Cilium proteomics reveals Numb as a positive regulator of the Hedgehog signaling pathway
Authors: Liu Xiaoliang , Yam Patricia T. , Schlienger Sabrina , Cai Eva , Zhang Jingyi , Chen Wei-Ju , Gutierrez Oscar Torres , Amilburu Vanesa Jimenez , Ramamurthy Vasanth , Ting Alice Y. , Branon Tess C. , Cayouette Michel , Gen Risako , Marks Tessa , Kong Jennifer H. , Charron Frédéric , Ge Xuecai 
Published: October 2022

SUMMARYThe transduction of Hedgehog (Hh) signaling relies on the primary cilium, a cell surface organelle serving as a signaling hub for the cell. Using proximity labeling and quantitative proteomics, we identified Numb as a new ciliary protein that positively regulates Hh signaling. Numb localizes to the ciliary pocket and acts as an endocytic adaptor to incorporate Ptch1 into clathrin-coated vesicles, thereby promoting Ptch1 exit from the cilium, a key step in Hh signaling activation. Numb loss hampers Sonic Hedgehog (Shh)-induced Ptch1 departure from the cilium, resulting in reduced activation of Hh signaling. Numb loss in spinal neural progenitors reduces Shh-induced differentiation into Nkx2.2-positive progenitors, a process reliant on high Hh signaling activity. Genetic ablation of Numb in the developing cerebellum impaired the proliferation of granule cell precursors, a Hh-dependent process, resulting in reduced cerebellar size. This study highlights Numb as a critical regulator of Ptch1 levels in the cilium during Hh signal activation and demonstrates the key role of ciliary pocket-mediated endocytosis in modulating the transduction of cell signaling.