bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sick of social status: A Bourdieusian perspective on morbidity and health inequalities
Authors: Balaj Mirza , Eikemo Terje A. 
Published: July 2022

AbstractSelf‐reported health (SRH) is one of the most frequently used measures for examining socioeconomic inequalities in health. Studies find that when faced with ‘identical objective health’, individuals in lower socioeconomic groups consistently report worse SRH than those in higher socioeconomic groups. Such findings are often dismissed as being the result of reporting bias, and existing literature dominated by the biomedical conception of SRH has not investigated the underlying social mechanisms at work. To address this limitation, drawing on the work of Bourdieu we employ a relational thinking between health and social position. By way of multiple correspondence analysis, we construct social space of health determinants for three European countries from different welfare states and map the trajectories of educational groups experiencing similar levels of morbidity and their relation to SRH. Differences in SRH observed among social groups for the same level of morbidity are understood in relation to the position and the relative power of individuals in different educational groups to maintain or improve their social conditions, especially with increasing levels of health loss. Our analysis indicates that reporting differences in SRH among educational groups emerges from objectively healthy individuals and follows differences in accumulation of social advantages and disadvantages.
Grammatical Coding and the Discursive Construction of Participants: Spanish Passives in Written Press News Discourse
Authors: Aijón Oliva Miguel A. 
Published: July 2022

AbstractThis paper presents a comparative analysis of two Spanish constructions that are usually characterised as passive, namely the periphrastic or attributive passive – formed with the verbser‘be’ plus a participle – and the reflexive passive – formed with third‐person reflexive cliticse. An isomorphic functional approach is adopted whereby the inherent syntactic‐semantic features of each construction are considered to be at the basis of their discourse‐pragmatic uses. Using a corpus of local written news pieces from the Peninsular town of Salamanca, the grammatical expression of both the initiators and the endpoints of events in each construction is quantitatively and qualitatively analysed, paying special attention to their variable encoding and placement within the clause and the semantic correlates of formal variation. While attributive passives are used to predicate transitive events of topical endpoints, reflexive passives often conceptualise events as thetic, reducing transitivity and defocusing initiators. These meanings are projected onto the discourse‐pragmatic domain by favouring different interpretations of the role of human participants, particularly with respect to their involvement in events amenable to negative judgements. This supports the hypothesis that the syntax and semantics of each grammatical construction are undetachable from its communicative potential in specific contexts.
Ancestral relatedness and visits between national leaders: Evidence from China†
Authors: Yan Jiaqiang , Zhou Yonghong 
Published: July 2022

AbstractThis study explores the factors that affect visits between national leaders in the world, shedding light on their ancestral origins. We combine data on visits involving Chinese leaders from 1993 to 2013 with genetic distance that captures ethnic differences transmitted intergenerationally. Empirical analysis shows that there are more visits between Chinese leaders and leaders of countries that have smaller genetic distance to China. Furthermore, the impact of genetic distance is achieved primarily through trade and positioning of political relationships, which are proxies for economic and political exchanges, respectively. Our findings show that ancestral relatedness plays an important part in modern diplomatic activities.
Development and validation of the linked color imaging classification for endoscopic prediction of colorectal polyp histology
Authors: Min Min , Ning Shou Bin , Hu Duan Min , Hayashi Yoshikazu , Liu Yan 
Published: July 2022

ObjectiveLinked color imaging (LCI) is a recently developed technique that emphasizes differences in mucosal color. In this study we aimed to develop a LCI classification based on the Narrow‐band Imaging International Colorectal Endoscopic Classification for predicting colorectal polyp histology and evaluate the validity and performance of the endoscopists in differentiating hyperplastic polyps from adenomas using the LCI classification.MethodsA workshop involving six international experts from China and Japan with substantial experience with LCI developed the classification. Three experienced and seven less‐experienced endoscopists used the LCI images to predict the histology of polyps independently, recording their degrees of confidence in these predictions before and after completing the training test for the LCI classification.ResultsOf the 50 polyps included, 30 (60.0%) were adenomas. Overall diagnostic accuracy before training was 75.4% (95% confidence interval [CI] 71.4%–79.1%), which increased to 85.2% (95% CI 81.8%–88.2%) after training. After training, the experienced and less‐experienced endoscopists achieved an overall accuracy of 87.3% and 84.3% for the prediction of polyp histology. Polyp prediction using the color criterion alone had the highest specificity and positive predictive value, whereas the vessel criterion achieved the highest accuracy and negative predictive value among all three individual LCI criteria. After training, both the experienced and less‐experienced endoscopists had high degrees of interobserver agreement.ConclusionsWe developed and validated the first LCI classification for endoscopic differentiation of adenomas and hyperplastic polyps. The LCI classification significantly improved the diagnostic accuracy of colorectal polyps.
Effect of Restoration on Plant Greenness and Water Use in Relation to Drought in the Riparian Corridor of the Colorado River Delta
Authors: Nagler Pamela , Sall Ibrahima , Barreto‐Muñoz Armando , Gómez‐Sapiens Martha , Nouri Hamideh , Chavoshi Borujeni Sattar , Didan Kamel 
Published: July 2022

ABSTRACTRevitalization of the Colorado River delta riparian corridor and increasing riparian plant greenness and water use may be accomplished by added water and restoration efforts to offset declines measured since 2000 by Landsat. We use the two‐band Enhanced Vegetation Index (EVI2; a proxy for greenness) and evapotranspiration (ET, mm/day) using EVI2 and potential ET(ETo) from Yuma Valley. We assess if restoration with only 7.5% landcover had an impact on the unrestored reach‐level landcover by measuring these two metrics, EVI2 and ET(EVI2) by comparing restored and unrestored areas. A key finding is that over 21‐years EVI2 in the unrestored corridor decreased by 23.6% and ET(EVI2) decreased by 32% (0.87 mm/day). Since 2011, the unrestored reaches lost EVI2 (11%) and −0.73 mm/day ET(EVI2) (28%), but restored sites increased in EVI2 (36%) and 0.58 mm/day ET(EVI2) (20%). Water delivered to restored sites increased EVI2 by 33.6% and 1.29 mm/day ET(EVI2) (58%). EVI2 and ET(EVI2) as a function of the Standardized Precipitation Evapotranspiration Index for drought periods highlight that restored and unrestored sites respond differently. Unrestored reaches are in decline; restored sites show increases in EVI2 and ET(EVI2). Restored sites do not have a significant impact on unrestored adjacent area, but smaller surface flows, a greater reliance on directed agricultural return flows, and deliveries of water to active restoration sites have revitalized habitat and increased ecosystem services in the delta.
How does mandatory CSR reporting affect supply chain? A new perspective from suppliers
Authors: Zhong Qinlin , Jiang Fuxiu , Li Dan , Yuan Chun 
Published: July 2022

AbstractExploiting a quasi‐natural experiment which mandates a subset of Chinese listed firms to report corporate social responsibility (CSR) activities, this paper examines how mandatory CSR disclosure affects suppliers' willingness to extend trade credit. We document that mandatory CSR disclosure firms suffer a significant shrinking in the volume of trade credit, which is driven by the supply side instead of the demand side. Further mechanism analyses reveal that both financial condition deterioration and interest conflicts contribute to adverse policy effects. These two factors negatively impact the credit quality of mandatory firms and then weaken credit quality after the mandate subsequently undermines suppliers' willingness to lend. Additionally, the negative association between mandatory CSR disclosure and trade credit is mainly concentrated on highly policy‐exposed corporates, that is, state‐owned enterprises (SOEs) and high‐polluting firms. Our work innovatively evaluates CSR effects from the perspective of suppliers, which provides a new insight into CSR management along the supply chain for academics and practitioners.
Intermediate fragmentation surrounding vineyards favours the Coleoptera community within the crop
Authors: Taranto Luisa , Rodrigues Isabel , Santos Sónia , Villa María , Pereira José Alberto 
Published: July 2022

Abstract
Insects of the order Coleoptera play an essential role in agricultural sustainability by supporting many ecosystem services (such as biological control, nutrient cycling or pollination). In agroecosystems, the Coleoptera community may be influenced by the surrounding landscape, which can provide living resources, like food or shelter, during different seasons, originating spillover movements between different environments.
The present study aimed to evaluate the response of the Coleoptera community to the landscape surrounding vineyards at different buffers. For that, Coleoptera were sampled in six wine protected designation of origin (PDO) regions of Portugal (35 vineyards), and landscape configuration and composition metrics were calculated at buffers of 500, 750, 1000, 1500 and 2000 m radii around the vineyards.
In total, 2954 Coleoptera individuals belonging to 36 families were collected. The most abundant families were Chrysomelidae, Coccinellidae and Latridiidae. Results indicated that intermediate habitat fragmentation levels, particularly in semi‐natural areas and vineyards, favoured Coleoptera biodiversity in vine‐producing regions. Moreover, the range of activity of Coleoptera seems to be larger than 1000 m.
This work constitutes an important contribution to understanding the response of the Coleoptera community to the landscape context in vineyards in Portugal and contributes to the theoretical framework about the influence of habitat fragmentation on biodiversity.
Prognostic significance of the preoperative lymphocyte to C‐reactive protein ratio in patients with stage III colorectal cancer
Authors: Eren Tunc 
Published: July 2022

AbstractBackgroundStage III colorectal cancer (CRC), which accounts for approximately one third of all CRC cases, is associated with worsened prognosis. The aim of this study was to compare the preoperatively measured systemic inflammatory markers and to define the most significant marker in terms of its prognostic value in stage III CRC.MethodsSurgically treated stage III CRC patients were included. Demographics, preoperatively measured Glasgow prognostic score (GPS), neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), lymphocyte/C‐reactive protein ratio (LCR) and C‐reactive protein/albumin ratio (CAR) values, clinicopathological features, surgical, oncological and survival outcomes were recorded and statistically analysed.ResultsThe study group of 102 patients consisted of 65 (63.7%) men and 37 (36.3%) women with a median age of 64 (range: 26–89). The mean follow‐up period was 42.8 ± 30.5 (range: 6–107) months. Overall survival (OS) and disease‐free survival (DFS) rates were 71.6%, and 67.7%, respectively. Elevated CRP, GPS 2, LCR ≤ 0.530, CAR ≥ 0.080, higher numbers of metastatic lymph nodes and N2b nodal status were detected to impair DFS (P = 0.001, P = 0.015, P = 0.001, P = 0.001, P = 0.001 and P = 0.043, respectively). Variables including GPS 2, PLR≥190.83, CAR≥0.045, LCR≤0.684, surgical site infection and longer hospital stay decreased OS (P = 0.004, P = 0.002, P = 0.005, P = 0.001, P = 0.001 and P = 0.001, respectively). According to multivariate analysis; PLR ≥ 190.83 was associated with three times [HR: 2.892 (95% CI: 1.100–7.602), P = 0.031], and LCR ≤ 0.684 was associated with four times [HR: 3.919 (95% CI: 1.130–13.592), P = 0.031] greater risk of cancer‐related mortality.ConclusionAs an independent prognostic factor, LCR had the highest impact on predicting survival after curative resection for stage III CRC.
Investigating the effect of optimal cytoreduction in the context of platinum sensitivity in high‐grade serous ovarian cancer
Authors: Cardillo Nicholas , Devor Eric , Calma Christian , Pedra Nobre Silvana , Gabrilovich Sofia , Bender David P. , Goodheart Michael , Gonzalez‐Bosquet Jesus 
Published: July 2022

AbstractIntroductionThe survival benefits of surgical cytoreduction in ovarian cancer are well‐established. However, the surgical outcome has never been assessed while controlling for the efficacy of chemotherapy. This leaves the possibility that cytoreduction may not be beneficial for patients whose cancer does not respond well to adjuvant treatment. We sought to answer whether surgical cytoreduction independently improves overall survival when controlling for chemotherapy outcome.Material and MethodsWe performed a retrospective case–control study using our institution's ovarian cancer database to evaluate the effect of optimal cytoreduction on advanced stage, high‐grade serous ovarian cancer. Patients' characteristics were compared using both univariate and multivariate regression modeling to assess for independent predictors of overall survival.ResultsA total of 470 patients were assessed for inclusion; 234 responders to chemotherapy and 98 nonresponders. Significant survival characteristics were identified and included in the multivariate analysis. Independent predictors of survival in the multivariate analysis were age, responder status, optimal cytoreduction, neoadjuvant chemotherapy, and number of chemotherapy cycles. Kaplan–Meier survival curves showed improved survival for both patients who responded to chemotherapy and for those undergoing optimal cytoreduction (p < 0.001). We also demonstrated improved survival for patients receiving optimal cytoreduction among both nonresponders and responders (p < 0.001).ConclusionsOur analysis shows that patients who undergo optimal cytoreduction have an overall survival benefit regardless of their response to chemotherapy. Therefore, cytoreduction should be considered in all patients, even in those with advanced disease, if an optimal result can be achieved. This study was underpowered to assess patients who received neoadjuvant chemotherapy as a separate subgroup, but the order of treatment was controlled for in the overall analysis.
Opium trade and use during the Late Bronze Age: Organic residue analysis of ceramic vessels from the burials of Tel Yehud, Israel
Authors: Linares Vanessa , Jakoel Eriola , Be’eri Ron , Lipschits Oded , Neumann Ronny , Gadot Yuval 
Published: July 2022

AbstractOrganic residue analysis was conducted on various vessels from burials at Tel Yehud, Israel. The analyses led to new reliable evidence for the presence of opioid alkaloids and their decomposition products. This research revitalizes a decades‐old discussion on the presence and function of the opium trade across a cultural region of utmost significance in the Ancient Near East and the use and role of Base‐Ring juglets during the Late Bronze Age IIA (14th century bce). Furthermore, it was found that opium storage was not limited to Base‐Ring juglets. Opium was possibly diluted into storage jars and juglets, signifying the importance of opium utilization at a larger scale during this period.
Patient reporting of sexual adverse events on an online platform for medication experiences
Authors: Gordijn Rineke , Wessels Wendela , Kriek Esther , Nicolai Melianthe P. J. , Elzevier Henk W. , Visser Loes , Guchelaar Henk‐Jan , Teichert Martina 
Published: July 2022

AimsFor >300 drugs, sexual side effects are included in the drug information leaflet. As sexual adverse events (sAEs) may be more easily shared at online medication platforms, patient‐reported drug experiences may add to the current knowledge on sAE experiences. This study evaluated patient reports from the online platform mijnmedicijn.nl for the frequency of sAE reporting, sex differences concerning sAEs and to assess drugs with disproportional sAE reporting.MethodsOn the online platform, terms for sAEs as used by patients were collected with a poll. Subsequently, drug reports posted between 2008 and 2020 were searched for sAEs with the identified terms. From the retrieved reports, the sAE frequencies and complaints and reporting odds ratios (ROR) were calculated, stratified for sex and drug (class). sAE reporting was considered disproportional frequent if the lower 95% confidence interval bound of the ROR >2.0.ResultsFor 189 drugs, sAEs were identified in 2408 reports (3.9%). Women posted 1383 reports (3.5% of all female reports) and men 1025 (4.7%). Almost half of the sAE reports addressed antidepressants: 586 reports of women (ROR 4.2; 95%CI 3.8–4.7) and 510 reports of men (ROR 7.5; 95%CI 6.6–8.5). Disproportional high numbers of sAE reports were found for 27 drugs, mostly antidepressants, hormonal contraceptives and drugs used in benign prostatic hyperplasia. Of these drugs with frequent sAEs, 7 had low sAE risks in their professional drug information.ConclusionOne in 25 drug reports on mijnmedicijn.nl included sAEs. The sAEs were reported frequently for antidepressants, contraceptives and drugs used in benign prostatic hyperplasia.
Telehealth delivery of paediatric rehabilitation for children with neurodisability: A mixed methods realist evaluation of contexts, mechanisms and outcomes
Authors: Graham Fiona , Williman Jonathan , Sutherland Lena , Wijninckx Morgan 
Published: July 2022

AbstractBackgroundTeledelivery of rehabilitation services has been proposed as a cost‐effective option for supporting children with neurodisability and their families. However, little is understood of the conditions that support uptake of telehealth in paediatric rehabilitation, what is delivered during telehealth or perceptions of its outcomes. The aim of this study was to identify the context, process and outcomes of telehealth for children with neurodisability and their families. A secondary objective was to identify if variations in these aspects of telehealth occurred for Māori, the indigenous people of New Zealand.MethodA mixed‐methods, three phase, realist evaluation identified context‐mechanism‐outcome configurations (CMOcs) of telehealth. In Phase 1, the Determinants of Implementation Behaviour Questionnaire indicated factors affecting practitioner uptake of telehealth (Context). In Phase 2, a casenote audit identified ‘practitioner input’ during telehealth (Mechanism). Phase 3 interviews with practitioners and parents explored ‘parent response’ to telehealth and practitioner and parent perceptions of its value (Mechanism and Outcomes). Subgroup analyses for Māori were planned.ResultsFrom Phase 1, practitioners (29/37, 78%) intended to use telehealth; however, few did so regularly (7/37, 22%). Positive experiences of telehealth were described by all practitioners (n = 5) and families (n = 7) in Phase 3. CMOcs explained that practitioners' offering of telehealth occurred when practitioners were confident, valued access to therapy over the familiarity of in‐person delivery, and when practitioners used coaching‐style communication. Parents were receptive to telehealth when they trusted practitioners, felt listened to and were offered telehealth as a choice. When telehealth occurred, access to therapy was timely and more consistent than in‐person delivery. Child outcomes appeared to be positive. Confidence in offering telehealth to Māori was low.ConclusionsInitiatives to improve uptake of telehealth in paediatric rehabilitation should focus on creating conditions for practitioner implementation. Training in telehealth should include engagement with Māori. Adequate workspace and workplace culture change are required if telehealth is to be offered beyond the current ‘early adopters’.
The impact of monoclonal antibody drugs on healthcare economics in the treatment of multiple sclerosis and neuromyelitis optica spectrum disorders
Authors: Ohashi Takashi 
Published: July 2022

AbstractThe launch of highly efficacious monoclonal antibody (mAb) drugs has profoundly changed the therapeutic strategy for multiple sclerosis and neuromyelitis optica spectrum disorders (NMOSD). However, the newly developed mAb drugs, especially those used in treating NMOSD, are quite expensive, resulting in a significant medical and economic burden. Early use of these drugs is expected to reduce the frequency of relapse and the accumulation of disability, preserve the quality of life of patients, and improve their life expectancy. In selecting therapeutic drugs, it is necessary not only to consider the efficacy and safety of the drugs, but also to consider the cost‐effectiveness of each drug for each patient, considering the economic aspects of health care. However, the cost‐effectiveness of mAb drugs in treating multiple sclerosis and NMOSD has not been fully verified. Japan is rapidly emerging as a hyper‐aged society, unlike any other in the world, and the rising cost of medical care is an urgent issue that needs to be addressed and resolved. Out‐of‐pocket expenses of individual patients are not a major issue in Japan as medical, costs for multiple sclerosis and NMOSD are subsidized by public medical insurance; however, the judicious use of mAb drugs is required to ensure cost‐effectiveness.
Chest three‐dimensional‐computed tomography imaging data analysis for the variation of exercise capacity after lung lobectomy
Authors: Ozeki Naoki , Iwano Shingo , Nakamura Shota , Kawaguchi Koji , Mizuno Yota , Inoue Takayuki , Nagaya Motoki , Chen‐Yoshikawa Toyofumi Fengshi 
Published: July 2022

AbstractBackgroundPostoperative loss of exercise capacity and pulmonary function is a major concern among lung cancer patients. In this study, the time for a stair‐climbing to 12‐m height was used to investigate whether preoperative chest 3D‐computed tomography (CT) could be a useful tool for predicting postoperative variations in exercise capacity and pulmonary function.MethodsSeventy‐eight patients undergoing lobectomy for suspected stage I lung cancer were prospectively enroled. Preoperatively, lobe volume and low attenuation volume (LAV) were evaluated using the SYNAPSE VINCENT system. Preoperative data on stair‐climbing time, spirometry and diffusing capacity of the lung for carbon monoxide (DLCO) at baseline and 6‐month postoperative data were used to evaluate variations in exercise capacity and pulmonary function. Maximal oxygen uptake (VO2t) was evaluated based on the stair‐climbing time.ResultsSignificant differences in the variation of exercise capacity at 6 months postoperatively were found between the groups categorized by target lobe volume and LAV status: The large volume/LAV (+) group had a greater decline in VO2t. Mean loss of VO2t was −6.2%, −1.4%, −1.6% and −0.1% in the large volume/LAV (+), large volume/LAV (−), small volume/LAV (+) and small volume/LAV (−) groups, respectively. The large volume/LAV (−) group had a greater decline in forced expiratory volume in 1 s. The small volume/LAV (+) group showed a reduced decline in the DLCO.ConclusionsAnalysis of chest 3D‐CT scans is a potential tool for predicting the loss of exercise capacity and pulmonary function after lung lobectomy.