bluuebunny/crossref_metadata_2025_split huggingface dataset:
UNA PROPUESTA CONCEPTUAL-TEÓRICA PARA ENTENDER LAS MEDIDAS EN MATERIA DE POBLACIÓN EN COSTA RICA. SEGUNDA MITAD DEL SIGLO XX
Authors: Carballo Murillo Natalia 
Published: February 2022

El objetivo de este artículo es proponer un marco conceptual y teórico para entender las percepciones, las actitudes y los tipos de masculinidades como aspectos que pueden presentarse entre la población y la adopción de medidas en materia de población en Costa Rica durante la segunda mitad del siglo xx. La construcción de la propuesta se hizo a partir de la revisión de bibliografía secundaria. La principal reflexión es, a pesar de que en Costa Rica no hubo una política con objetivos específicos para controlar la natalidad, si se dio la creación de una serie de instituciones con objetivos en materia de población. En el actuar individual ante dichas instituciones y objetivos, mediado por el contexto y por el impulso del Estado (de todo el aparato desarrollado entre las instituciones nacionales e internacionales) se ponen en evidencia las percepciones, actitudes y roles de género, así como la influencia de actores como la iglesia católica.
A kulturális összehasonlító pszichológia 30 éve Magyarországon
Authors: Fülöp Márta 
Published: February 2022

A tanulmány célja a kulturális összehasonlító pszichológia szakterület elmúlt harminc évének áttekintése, a kutatási területek és az intézményesülés bemutatása. A rendszerváltás előtti tematikák rövid ismertetése után a rendszerváltás utáni, a rendszerváltás társadalmi-kulturális változásait feltárni kívánó kutatások sorozata következik. A rendszerváltás, a nemzetközi szakmai együttműködések felszabadításával lehetővé tette azt, hogy a korábban kutatott tematikák kibővüljenek és egyre több kutatónak nyíljon arra lehetősége, hogy egy-egy kutatás erejéig vagy akár kutatássorozatok formájában kulturális összehasonlító vizsgálatokat végezzen. Az utóbbi évtizedben Magyarország ugyancsak képviselteti magát a nagy, sok országra kiterjedő, kulturális összehasonlító kutatásokban is, így lehetővé válik számos pszichológiai konstruktum esetében a magyar válaszadókra jellemző pszichés működésmódok nemzetközi összehasonlításban történő elhelyezése.A tanulmány bemutatja azokat az intézményi központokat is, amelyek a kulturális összehasonlító kutatások jelenlegi magyarországi műhelyei, az ott dolgozó kutatókat és a jelenleg kutatott tematikákat.The aim of the paper is to review the past thirty years in the field of cultural comparative psychology, to present research areas and institutionalization. After a brief description of the topics before the change of regime, a series of post-change studies exploring the socio-cultural cha,nges of the change of regime follow. The change of regime, with the release of international professional collaborations, has made it possible to expand the topics previously researched and to give more and more researchers the opportunity to carry out cultural comparative studies to the extent of a single research or even in the form of a series of research. In the last decade, Hungary has also been represented in large, multi-country, comparative cultural research, thus making it possible to place the psychological functioning of Hungarian respondents in international comparisons in the case of many psychological constructs.The study also presents the institutional centers that are the current workshops of cultural comparative research in Hungary, the researchers working there and the topics currently being researched.
Pterostilbene promotes the osteogenic differentiation of MC3T3-E1 cells inhibited by H2O2 by activating the AMPK signaling pathways
Authors: Li Haiyan , Guo Jiang , Zhang Dong , Huang Jihong , Li Xuejia 
Published: February 2022

Osteoporosis is one of the common degenerative skeletal diseases whose essential mechanism is the imbalance between bone resorption and formation. Currently, the close coordination of signaling pathways at genetic level during bone development is a hot topic of osteoporosis research. The present study is focused on whether pterostilbene protects against hydrogen peroxide (H2O2)-induced osteoblastic cell apoptosis, oxidative stress, and reveals the related underlying mechanisms. MC3T3-E1 osteoblastic cells were cultured and treated with different concentrations of H2O2 (0–1 mM) along with or without pterostilbene, and MTT assay or Annexin V-FITC/propidium iodide staining was applied for measuring cell viability and apoptosis. The in vitro cellular antioxidant analysis was performed using 2,7-dichlorodihydrofluorescein diacetate assay and enzyme-linked-immunosorbent serologic assay against glutathione peroxidase and malondialdehyde. In addition, cellular alkaline phosphatase activity was executed by Alizarin Red S staining. Western blot assay was conducted to determine the expression levels of osteogenic-related markers, including type I collagen, osteopontin, runt-related transcription factor 2, and the 5' adenosine monophosphate-activated protein kinase (AMPK) signaling pathways related proteins. The key finding was that pterostilbene could attenuate the H2O2-induced cellular apoptosis and oxidative stress. Pterostilbene also promoted osteogenic differentiation in H2O2-treated MC3T3-E1 cells through activation of the AMPK pathway. In conclusion, pterostilbene blocked the H2O2-induced MC3T3-E1 cells dysfunction, indicating its potential to be a promising medication for treating osteoporosis.
Magnoflorine promotes Huh-7 cell apoptosis and autophagy by regulating PI3K/Akt/mTOR pathway
Authors: Xu Jifan , Du Bo , Liu Yunfeng , Tao Chonglin 
Published: February 2022

Hepatoma is a malignant tumor with high rates of heterogeneity, metastasis, and mortality. Currently, there is no effective treatment available for hepatoma. In order to treat advanced hepatoma in a better manner, new and more effective therapeutic targets still need to be developed. Magnoflorine (MGN) is a quaternary ammonium alkaloid with a variety of therapeutic properties. MGN inhibited the proliferation of lung cancer, breast cancer, glioma, and rhabdomyosarcoma cells, induced apoptosis, and blocked cell cycle. However, its possible effects on the progression of hepatoma are still indefinite. In this study, the effects of MGN on the progression of hepatoma in vitro and the underlying mechanisms were determined. MGN suppressed the proliferation, induced the autophagy, and stimulated the apoptosis of human hepatoma Huh-7 cells. Mechanically, MGN could regulate PI3K/AKT/mTOR pathway, which therefore affects the progression of hepatoma in vitro. Taken together, MGN affected Huh-7 cell proliferation, autophagy, and apoptosis, and might act as a promising therapeutic drug for treating hepatoma.
Consolidating Back Office with a Shared-Services Center:
Authors: Jovanovska Mimoza Bogdanoska , Tabakovska Nataša Blazeska , Grueski Dragan 
Published: February 2022

Purpose: The paper points out a novel approach to e-Government back-office reengineering based on creating a Shared-Services Center at the sectorial level. Design/Methodology/Approach: To prove the Shared-Services Center as a proper solution for e-Government back-office reengineering, the authors used the case study of the Housing Facilities Sector in the Republic of North Macedonia. The research process follows Kettingers et al.'s framework of IT-enabled change with a holistic data-driven approach. Findings: The study indicates a complex information flow between stakeholders, an abundance of the same information and data collected from local stakeholders, and enormous citizen and institutional burden. The e-Government back-office reengineering solution for the specific case study based on creating a Shared-Services Center overcomes the problem of data redundancy, radically simplifies the information flow, and reduces citizen burden in line with the "Once-Only" principle. Practical Implications: The paper shows that by observing the network of all relevant stakeholders at the sectorial level, based on the information flow of core data, back-office problems can be identified, whereby the Shared-Services Center proves itself as a suitable solution. It may be a prerequisite for further studies on back-office process reengineering at the sectorial level. Originality/Value: Publications concerning back-office research at the sectorial level and, as in our case, within the House Facility Sector are almost non existing in scientific literature. Considering that there is a lack of analyses based on information flow and visualization of the information-flow network at the sectorial level (before and after the reforms), this paper will add original value to scientific literature.
An Earthquake Simulator for New Zealand
Authors: Shaw Bruce E. , Fry Bill , Nicol Andrew , Howell Andrew , Gerstenberger Matthew 
Published: February 2022

ABSTRACTWe present an earthquake simulator for New Zealand. It uses the Rate-and-State Earthquake Simulator engine based on approximations of the rate-and-state friction equations. The full set of faults considered in the most recent New Zealand national seismic hazard maps are included in the simulator. New simulator methods are introduced that allow for the inclusion and interaction between upper plate faults and a subduction interface fault below them. The simulator generates sequences of complex slip events and a catalog of finite ruptures hundreds of thousands of years in length. Results from the simulator are evaluated through statistical testing and comparison with geological and geophysical observations. These evaluations include a spatial comparison against historical earthquakes, a comparison against rates of events in the instrumental catalog, and a comparison against scaling relations. Consistency of the model with these measures is generally found, though some differences with productivity is noted, due to incomplete modeling of subducting slab features like geodetically inferred spatially dependent creep and dense faulting in Bay of Plenty faults. Significant emergent aspects of the resulting synthetic catalog are discussed. These include substantial variability over instrumental catalog timescales, clustering of large events in space and time, and spontaneous ruptures that break both the upper crustal faults and subduction interface coseismically. An online repository provides the model output, and an additional site provides python code for reproducing some of the figures in this article and tools for further model output analysis.
GITEC: A Generalized Inversion Technique Benchmark
Authors: Shible Hussein , Hollender Fabrice , Bindi Dino , Traversa Paola , Oth Adrien , Edwards Benjamin , Klin Peter , Kawase Hiroshi , Grendas Ioannis , Castro Raul R. , Theodoulidis Nikolaos , Gueguen Philippe 
Published: February 2022

ABSTRACT
Generalized inversion techniques (GITs) have become popular for determining seismological parameters (e.g., source, attenuation, and site response), particularly in low-to-moderate seismicity regions. Indeed, GITs can potentially provide reliable site-response estimates when a minimum number of recordings is available, as well as valuable information about source parameters and regional attenuation characteristics. Significant advances have been made on GITs in which different approaches and hypotheses were investigated, such as the application of “nonparametric” and “parametric” inversion schemes. In this context, several scientific questions have arisen that depend on the final scope of the GITs: What is the optimal inversion strategy for a given dataset configuration? What is the impact of the different choices, assumptions, and implementations on the reliability of the results? Is it possible to quantify the associated epistemic uncertainties? Here, we have considered and compared the different approaches of GITs to improve the understanding of each for use in different applications. A methodological benchmark that includes different GIT methods and dataset configurations is set up to fulfill the objective, using a simple synthetic dataset, a French regional sparse dataset, and an Italian national dense dataset. The benchmark is developed in two phases: (1) phase I: a free phase with no common constraints; and (2) phase II: a constrained phase with unified reference conditions. Despite unifying the reference conditions in the different inversions, the variability was not reduced. Discrepancies are observed between different terms of GITs. Site responses appear to be the most robust estimates, compared to source and attenuation terms. The way that stress drops of earthquakes and quality factors for crustal attenuation are parameterized appears to lead to significant variability between different approaches. Finally, uncertainties are addressed by quantification of the inter-method variability for the different terms and parameters.
Análisis del Clima Laboral en el Instituto Superior Tecnológico Juan Bautista Aguirre en Tiempos de Pandemia
Authors: Apolo Robles Darwin Vicente , Méndez-Mantuano Marcel Oswaldo , Bodero Jiménez Keyla Ximena , Alvarado Fiallo Soraya Francisca , Huayamave Rosado Ángel Raúl 
Published: February 2022

La pandemia sigue afectando al componente social de las personas, debido a las restricciones, los distanciamientos y los confinamientos, provocando cambios drásticos en la forma de convivir con el entorno y en las interrelaciones laborales. Con estas perspectivas surge la necesidad de conocer y evaluar los entornos laborales durante la pandemia, con el objetivo de conocer las particularidades y conflictos que se desarrollan en esta nueva relación laboral. La educación se ha adaptado a la modalidad de teletrabajo para los docentes y de teleeducación para los estudiantes, donde ambos grupos humanos han tenido que ajustar los entornos de su residencia para desarrollar las diferentes actividades. La presente investigación tiene como propósito analizar el clima laboral en el Instituto Superior Tecnológico Juan Bautista Aguirre de la ciudad de Daule (Ecuador) durante la pandemia de covid-19; para ello se realizó una encuesta a 61 docentes voluntarios, en la cual se abordaron las dimensiones de: sentido de pertenencia, relaciones entre compañeros, satisfacción, eficacia y eficiencia, liderazgo, reconocimiento y oportunidades de desarrollo e innovación. Adicionalmente se realizó una entrevista a la máxima autoridad de la institución para conocer las perspectivas gerenciales relacionadas al clima laboral. De manera general se determinó el promedio porcentual de las dimensiones, donde el 73% de la valoración fue positiva, mientras que el 27% fue negativa.

The pandemic continues to affect the social component of people, due to restrictions, distancing, and confinement, causing drastic changes in the way of living with the environment and in work interrelationships. With these perspectives arises the need to know and evaluate the work environments during the pandemic, with the aim of knowing the particularities and conflicts that develop in this new employment relationship. Education has been adapted to the modality of telework for teachers and tele-education for students, where both human groups have had to adjust the environments of their residence to develop the different activities. The purpose of this research is to analyze the work environment at the Juan Bautista Aguirre Higher Technological Institute in the city of Daule (Ecuador) during the covid-19 pandemic; For this, a survey was carried out on 61 volunteer teachers, in which the dimensions of: sense of relevance, peer relationships, satisfaction, effectiveness and efficiency, leadership, recognition and opportunities for development and innovation were addressed. Additionally, an interview was conducted with the highest authority of the institution to learn the managerial perspectives related to the work environment. In general, the average percentage of the dimensions was determined, where 73% of the assessment was positive, while 27% was negative.
Genre et Acces au Foncier : Etude Comparative des Modes d’Acquisition de la Terre chez les Femmes du Sud et du Nord de la Cote d’Ivoire : Cas d’Akoupé et Becouéfin ; Nahoualakaha et Torgokaha
Authors: Simon Affessi Adon , Kabié Yapo Anthelme , Georgette Brou Gnangon 
Published: February 2022

La présente étude s’est intéressée à la question du mode d’accès à la terre par les femmes du Nord, et celles Sud de la Côte d’Ivoire. Elle se propose de comparer les déterminants socioculturels de l’accessibilité différentiée à la terre chez les femmes Sénoufo et Akyé. La population ciblée pour l’étude menée entre Avril 2021 et Juin 2021 est constituée d’autorités coutumières, des leaders communautaires et des femmes résidentes ou non, et membres ou non des coopératives agricoles. La démarche sur laquelle s’est appuyée cette étude est de type qualitatif orientée selon la méthode comparative et conduite à l’aide d’entretien individuel, de focus groups et d’observation participante. La théorie comparative a été convoquée pour mieux faire la comparaison entre ces deux entités (femme du Nord et femme du Sud) et apporter un meilleur éclairage sur la question de leur accès à la terre. L’analyse de la question de l’accessibilité de la terre a montré que les femmes du Sud de la Côte d’Ivoire accèdent de plus en plus à la terre car les normes, règles et valeurs de cette société ont connu des mutations tendant à intégrer la femme dans le partage de la terre même si cela ne se fait pas de façon équitable entre l’homme et la femme. Chez les femmes du Nord de la Côte d’Ivoire, l’accès définitif à la terre est quasiment impossible à cause de la rigidité des valeurs, normes et règles qui régulent cette société.

This study looked at the question of how women in the north and south of Côte d'Ivoire access land. It compares the socio-cultural determinants of differential access to land among Senoufo and Akye women. The target population is made up of the customary authorities, community leaders, and women who may or may not be residents or members of agricultural cooperatives. The study was conducted from April to June. The approach of this study was qualitative and comparative, using individual interviews, focus groups and participant observation. The comparative theory was used to better compare these two entities (women from the North and women from the South) and to shed more light on the issue of their access to land. The analysis of the issue of access to land showed that women in the south of Côte d'Ivoire are gaining access to land because the norms, rules and values of this society have changed to include women in the sharing of land, even if this is not done in an equitable manner between men and women. Among women in the north of Côte d'Ivoire, definitive access to land is almost impossible because of the rigidity of the values, norms and rules that regulate this society.
Outcomes of Nonoperatively Treated Pediatric Supracondylar Humeral Fractures at the Nkhotakota District Hospital, Malawi
Authors: Mlinde Elijah , Amlani Lahin M. , May Collin J. , Banza Leonard N. , Chokotho Linda , Agarwal-Harding Kiran J. 
Published: February 2022

Background:
Displaced supracondylar humeral fractures (SCHFs) benefit from closed reduction and percutaneous pinning. In Malawi, many SCHFs are treated nonoperatively because of limited surgical capacity. We sought to assess clinical and functional outcomes of nonoperatively treated SCHFs in a resource-limited setting.

Methods:
We retrospectively reviewed all patients with SCHFs treated at Nkhotakota District Hospital (NKKDH) in Malawi between January 2014 and December 2016. Patients subsequently underwent clinical and functional follow-up assessment.

Results:
We identified 182 children (54% male, mean age of 7 years) with an SCHF; 151 (83%) of the fractures were due to a fall, and 178 (98%) were extension-type (Gartland class distribution: 63 [35%] type I, 52 [29%] type II, and 63 [35%] type III). Four patients with type-I fractures were treated with an arm sling alone, and 59 were treated with straight-arm traction to reduce swelling and then splint immobilization until union. All 119 of the patients with Gartland type-II and III or flexion-type injuries were treated with straight-arm traction, manipulation under anesthesia without fluoroscopy, and then splint immobilization until union. A total of 137 (75%) of the patients were available for follow-up, at a mean of 3.9 years after injury. The Flynn functional outcome was excellent for 39 (95%) with a type-I fracture, 30 (70%) with type-II, and 14 (29%) with type-III. The Flynn cosmetic outcome was excellent for 40 (98%) with a type-I fracture, 42 (98%) with type-II, and 41 (84%) with type-III. Forty (98%) of the children with a type-I fracture, 41 (95%) with type-II, and 32 (65%) with type-III returned to school without limitation. Controlling for sex, delayed presentation, medical comorbidities, injury mechanism, and skin blistering/superinfection during traction, patients with type-II fractures were 5.82-times more likely (95% confidence interval [CI], 1.71 to 19.85) and those with type-III fractures were 9.81-times more likely (95% CI, 3.00 to 32.04), to have a clinical complication or functional limitation compared with patients with type-I fractures.

Conclusions:
Nonoperative treatment of type-III SCHFs resulted in a high risk of clinical complications or functional impairment. These results illustrate the urgent need to increase surgical capacity in low-income countries like Malawi to improve pediatric fracture care.

Level of Evidence:
Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
Nonlinear suboptimal attitude control law for near-space hypersonic vehicle: Eigenvalue analysis and weight matrices design
Authors: Mi Peichao , Wu Qingxian , Wang Yuhui 
Published: February 2022

Abstract
This paper considers a nonlinear suboptimal control problem for a near-space hypersonic vehicle's (NSHV's) attitude dynamics. The least-square and stable manifold methods first solve an unconstrained approximately optimal control law corresponding to the nonlinear attitude model. Then, to further meet the dynamic performance requirement of the attitude control system, a novel strategy based on the Koopman operator, symplectic geometric theory, and the stable manifold theorem is proposed to approximate the eigenvalues of the closed-loop nonlinear unconstrained approximated optimal control system. The weight matrices in the optimal performance index, which directly determine the output responses of the nonlinear attitude dynamics, can be appropriately designed according to the eigenvalues. The final control law considers the actuator constraints. The NSHV's closed-loop attitude control system is proved to be locally exponentially stable, and the suboptimality of the control law is analyzed. Numerical simulation demonstrates the effectiveness of the proposed scheme.