bluuebunny/crossref_metadata_2025_split huggingface dataset:
An empirical study on repeat consumer's shopping satisfaction on C2C e-commerce in Japan: the role of value, trust and engagement
Authors: Moriuchi Emi , Takahashi Ikuo 
Published: April 2022

PurposeTechnology has advanced and led the revolution of the online e-commerce industry through various online platforms. These online platforms were integrated to enhance customer's shopping experience, promoting different business models including consumer-to-consumer (C2C) secondary e-commerce market. This new online business model has been gaining interest in both academia and industry due to potential opportunities and challenges to serve customers effectively. This study aims to draw upon the means-end theory to test a conceptual model to understand the role of engagement between different types of trust and satisfaction toward shopping on C2C e-commerce.Design/methodology/approachA quantitative survey method was developed to test the antecedents and mediator of C2C customer satisfaction. A panel service was used to collect the dataset (n = 294) to test the proposed extended means-end chain theory (MEC) model.FindingsThe authors found that the role of trust toward the platform provider and the third-party seller differs based on the perceived value (functional and emotional) and impact of trust on satisfaction. This study provides a rich conceptualization of an instrument for a C2C experience that can serve as a starting point for future research to investigate the antecedents and impacts of the C2C context.Research limitations/implicationsBecause of the chosen research approach, the research results may lack generalizability. Therefore, researchers are encouraged to test the proposed hypotheses further in a different context (e.g. country).Practical implicationsThe paper includes implications for a guide to designing an effective online C2C retailing strategy.Originality/valueThis paper fulfills an identified need to study how engagement serves different role depending on the trust consumers have toward the intermediary vs the seller, which has a subsequent effect on consumer's satisfaction.
Change detection filter technique-based fault analysis of HVDC transmission line
Authors: Damala Rajesh Babu , Dash Ashish Ranjan , Patnaik Rajesh Kumar 
Published: April 2022

Purpose
This research paper aims to investigate the change detection filter technique with a decision tree-based event (fault type) classifier for recognizing and categorizing power system disturbances on the high-voltage DC (HVDC) transmission link.

Design/methodology/approach
A change detection filter is used to the average and differential current components, which detects the point of fault initiation and records a change detection point (CDP). The half-cycle differential and average currents on both sides of the CDP are sent through the signal processing unit, which produces the respective target. The extracted target indices are sent through a decision tree-based fault classifier mechanism for fault classification.

Findings
In comparison with conventional differential current protection systems, the developed framework is faster in fault detection and classification and provides great accuracy. The new technology allows for prompt identification of the fault category, allowing electrical grids to be restored as quickly as possible to minimize economic losses. This novel technology enhances efficiency in terms of reducing computing complexity.

Research limitations/implications
Setting a threshold value for identification is one of the limitations. To bring the designed system into stability condition before creating faults on it is another limitation. Reducing the computational burden is one of the limitations.

Practical implications
Creating a practical system in laboratory is difficult as it is a HVDC transmission line. Apart from that, installing rectifier and converter section for HVDC transmission line is difficult in a laboratory setting.

Originality/value
The suggested scheme’s importance and accuracy have been rigorously validated for the standard HVDC transmission system, subjected to various types of DC fault, and the results show the proposed algorithm would be a feasible alternative to real-time applications.
Ureteral metastasis of small cell lung cancer transformed from lung adenocarcinoma: A case report
Authors: Wang Yi , Li Ji , Luo Lei , Li Xiaoliang , Liu Qingsong , Wang Yan , Che Guowei , Xie Xiaoyang 
Published: April 2022

AbstractTargeted therapy offers a new option for patients with advanced lung adenocarcinoma patients. However, long‐term targeted therapy may transform lung adenocarcinoma into small cell lung cancer (SCLC). Herein, we report a 48‐year‐old female patient with pulmonary adenocarcinoma and ureteral metastasis which transformed from adenocarcinoma to SCLC after surgical and targeted therapies. She was diagnosed with invasive adenocarcinoma undergoing the surgery. Two years later recurrence and metastasis occurred and she was given targeted therapy with gefitinib and osimertinib. Two years after targeted therapy, a right ureteral mass (4.9 × 3.7 × 3.8 cm) pathologically diagnosed with SCLC was found, which indicated that the pathological subtype has changed from adenocarcinoma to SCLC. Ultimately, multiple metastases occurred after two cycles of chemotherapy consisting of cis‐platinum plus etoposide.
Zirconium cyclosilicate: An oral sorbent for potassium, four decades in the making
Authors: Ash Stephen R. 
Published: April 2022

AbstractHemoCleanse collaborated with Dr. John Sherman and Union Carbide in the 1980s to develop a cation exchanger with high selectivity for potassium and ammonium, for use in a wearable artificial kidney. Synthetic zeolites had unexpected solubility in this application but by 2000, UOP (a sister company of Union Carbide) had developed zirconium cyclosilicate (SZC). HemoCleanse performed early animal studies of SZC as an oral sorbent. These showed remarkable binding characteristics. HemoCleanse then obtained the license for SZC for medical applications, helped to form ZS Pharma, and collaborated in further animal studies and clinical trials. AstraZeneca purchased ZS Pharma in 2015, and SZC (Lokelma®) has now become an effective treatment for hyperkalemia in patients with kidney failure and cardiac conditions.
Late relapses in Hodgkin lymphoma – should we search for the needle in the haystack?
Authors: El‐Galaly Tarec Christoffer , Glimelius Ingrid 
Published: April 2022

Hodgkin lymphoma is among the most curable cancers. For patients in remission for 24 months, residual lifetime becomes close to that of the background population. However, late relapses can occur after several years and, as shown by Andersen et al., the outcomes are not always good.Commentary on: Andersen MD, Hamilton‐Dutoit S, Modvig L, Vase M, Christiansen I, Christensen JH, et al. Late recurrence of lymphoid malignancies after initial treatment for Hodgkin lymphoma – A study from the Danish Lymphoma Registry. Br J Haematol 2022;198:50‐61.
New configurations of labour insertion processes. The case of secondary technical and vocational education and training students in Chile
Authors: Valdebenito María José , Sepúlveda Leandro 
Published: April 2022

AbstractThis article presents the results of a longitudinal study that followed a sample of 1011 young people who completed their secondary technical and vocational education and training studies in Chile between 2011 and 2016. It adopts a mixed design that combines both quantitative and qualitative methodological strategies to analyse transitions and post‐study trajectories. Analysis has helped to identify the prevalence of non‐linear and unstructured transitions to the labour market. It has also shown the existence of education‐work links and employment alternatives that are generated in certain sectors as well as identified how these give rise to specific opportunity structures that affect on aspirations and career pathways. Results indicate that graduates of the industrial area of study experience more substantive educational integration and labour links following course completion due to greater levels of alignment between their training and the productive demands of the industrial sectors. However, their experiences over the medium term are fragmented and, thus, reflect those of their peers from other areas.
Life history of the humpnose big‐eye bream Monotaxis grandoculis
Authors: Pardee Cassandra , Wiley John 
Published: April 2022

AbstractThis study provides estimates of growth rate, longevity, maturity, spawning seasonality and mortality for Hawai'i's only lethrinid, the humpnose big‐eye bream (known as Mū in Hawai'i) Monotaxis grandoculis, a commercially and recreationally important species in Hawai'i and throughout the Indo‐Pacific. M. grandoculis reaches maturity at 303 mm fork length or 3.6 years of age for both sexes. Males were significantly larger than females for a given age. The von Bertalanffy growth parameters for males and females were L∞ = 506 mm fork length and von Bertalanffy growth coefficient (K) = 0.24 year−1, and L∞ = 427 mm fork length and K = 0.33 year−1, respectively. Both males and females reached ages over 20 years old, with a maximum age of 23 years. M. grandoculis had a distinct spawning season from May through August with corresponding elevated female gonadosomatic index. An age‐based multinomial catch curve indicated that the commercial exploitation rate (natural mortality/fishing mortality) was 0.48 year−1, which is considered below the overfishing limit.
The vomeronasal system in semiaquatic beavers
Authors: Tomiyasu Jumpei , Korzekwa Anna , Kawai Yusuke K. , Robstad Christian A. , Rosell Frank , Kondoh Daisuke 
Published: April 2022

AbstractIn contrast to the main olfactory system that detects volatile chemicals in the nasal air, the vomeronasal system can detect nonvolatile chemicals as well as volatiles. In the vomeronasal system, chemicals are perceived by the vomeronasal organ (VNO) projecting axons to the accessory olfactory bulb (AOB). Beavers (Castor spp.) are semiaquatic mammals that have developed chemical communication. It is possible that the beaver's anal gland secretions, nonvolatile and insoluble substances, may work as a messenger in the water and that beavers may detect the nonvolatile chemicals floating on the water surface via the VNO. The present study aimed to clarify the specificities of the beaver vomeronasal system by histologically and immunohistochemically analyzing the VNO and AOB of 12 Eurasian beavers (C. fiber). The VNO directly opened to the nasal cavity and was independent of a narrow nasopalatine duct connecting the oral and nasal cavities. The VNO comprised soft tissues including sensory and nonsensory epithelium, glands, a venous sinus, an artery, as well as cartilage inner, and bone outer enclosures. The AOB had distinct six layers, and anti‐G protein α‐i2 and α‐o subunits were, respectively, immunoreactive in rostral and caudal glomeruli layers indicating expressions of V1Rs and V2Rs. According to gene repertories analysis, the beavers had 23 and six intact V1R and V2R genes respectively. These findings suggested that beavers recognize volatile odorants and nonvolatile substances using the vomeronasal system. The beaver VNO was developed as well as in other rodents, and it had two specific morphological features, namely, disadvantaged contact with the oral cavity because of a tiny nasopalatine duct, and a double bone and cartilage envelope. Our results highlight the importance of the vomeronasal system in beaver chemical communication and support the possibility that beavers can detect chemicals floating on the water surface via the VNO.
Periodontitis links to concurrent systemic comorbidities among ‘self‐perceived health’ individuals
Authors: Zhao Dan , Wu Mei‐Zhen , Yu Shuk Yin , Pelekos George , Yiu Kai Hang , Jin Lijian 
Published: April 2022

AbstractBackground and ObjectiveOur recent work shows that periodontitis experience reflects host susceptibility to the onset of multiple systemic diseases and conditions. This cross‐sectional study further investigated whether and to what extent the existing periodontitis could reflect the concurrent presence of inflammatory comorbidities among ‘self‐perceived health’ individuals.Materials and MethodsThere were 115 ‘self‐perceived health’ adults who completed a questionnaire on demographic characteristics and lifestyles. Twenty medical diagnostic tests were then performed to detect eight common systemic diseases and conditions. Meanwhile, full‐mouth periodontal examination was undertaken, and the subjects were classified as two subgroups with or without Generalized Severe Periodontitis (Stages III/IV, generalized). The interlink of periodontal status and concurrent systemic comorbidities was assessed.Results98.3% (113/115) of the subjects exhibited at least one undiagnosed systemic disease/disorder. Of them, 52.2% (59/113) and 47.8% (54/113) concurrently presented with 1–5 or ≥6 abnormal test results, respectively. Overall, 96.5% (111/115) had periodontitis. Generalized Severe Periodontitis was present in 43.2% (48/111) of the periodontitis patients, and it was significantly associated with the profiles of abnormal test results after adjusting potential confounders (abnormal test results 1–5 vs ≥6; OR: 3.23, p = .012).ConclusionsThe present study shows that existing severe periodontitis could well reflect the concurrent presence of multiple inflammatory comorbidities. Oral and medical professionals can play proactive roles in enhancing health awareness and healthcare, through strong collaboration and teamwork.
Coronary microvascular dysfunction is common in patients hospitalized with COVID‐19 infection
Authors: Çalışkan Mustafa , Baycan Ömer Faruk , Çelik Fatma Betül , Güvenç Tolga Sinan , Atıcı Adem , Çağ Yasemin , Konal Oğuz , İrgi Tuğçe , Bilgili Ümmühan Zeynep , Ağırbaşlı Mehmet Ali 
Published: April 2022

AbstractBackground and AimsMicrovascular disease is considered as one of the main drivers of morbidity and mortality in severe COVID‐19, and microvascular dysfunction has been demonstrated in the subcutaneous and sublingual tissues in COVID‐19 patients. The presence of coronary microvascular dysfunction (CMD) has also been hypothesized, but direct evidence demonstrating CMD in COVID‐19 patients is missing. In the present study, we aimed to investigate CMD in patients hospitalized with COVID‐19, and to understand whether there is a relationship between biomarkers of myocardial injury, myocardial strain and inflammation and CMD.Methods39 patients that were hospitalized with COVID‐19 and 40 control subjects were included to the present study. Biomarkers for myocardial injury, myocardial strain, inflammation, and fibrin turnover were obtained at admission. A comprehensive echocardiographic examination, including measurement of coronary flow velocity reserve (CFVR), was done after the patient was stabilized.ResultsPatients with COVID‐19 infection had a significantly lower hyperemic coronary flow velocity, resulting in a significantly lower CFVR (2.0 ± 0.3 vs. 2.4 ± 0.5, p < .001). Patients with severe COVID‐19 had a lower CFVR compared to those with moderate COVID‐19 (1.8 ± 0.2 vs. 2.2 ± 0.2, p < .001) driven by a trend toward higher basal flow velocity. CFVR correlated with troponin (p = .003, r: −.470), B‐type natriuretic peptide (p < .001, r: −.580), C‐reactive protein (p < .001, r: −.369), interleukin‐6 (p < .001, r: −.597), and d‐dimer (p < .001, r: −.561), with the three latter biomarkers having the highest areas‐under‐curve for predicting CMD.ConclusionsCoronary microvascular dysfunction is common in patients with COVID‐19 and is related to the severity of the infection. CMD may also explain the “cryptic” myocardial injury seen in patients with severe COVID‐19 infection.
Magnetic resonance imaging assessed enteric motility and luminal content analysis in patients with severe bloating and visible distension
Authors: Gollifer Ruaridh M. , Taylor Stuart A. , Menys Alex , Zarate‐Lopez Natalia , Chatoor Dave , Emmanuel Anton , Atkinson David 
Published: April 2022

AbstractBackgroundGastrointestinal symptoms in functional gut disorders occur without any discernible structural gut abnormality. Preliminary observations on enteric MRI suggest possible abnormal content and motility of the terminal ileum (TI) in constipation‐predominant IBS (IBS‐C) with severe bloating, and in functional bloating and distension (FABD) patients. We investigated whether MRI can quantify differences in small bowel (SB) content and motility between patients and healthy controls (HCs).Methods11 IBS‐C (mean age 40 [21–52] years; 10 women) and 7 FABD (36 [21–56]; all women) patients with bloating and 20 HCs (28 [22–48]; 6 women) underwent enteric MRI, including dynamic motility and anatomical sequences. Three texture analysis (TA) parameters assessed the homogeneity of the luminal content, with ratios calculated between the TI and (1) the SB and (2) the ascending colon. Four TI motility metrics were derived. Ascending colon diameter (ACD) was measured. A comparison between HCs and patients was performed independently for: (1) three TA parameters, (2) four TI motility metrics, and (3) ACD.Key ResultsCompared with HCs, patients had TI:colon ratios higher for TA contrast (p < 0.001), decreased TI motility (lower mean motility [p = 0.04], spatial motility variation [p = 0.03], and area of motile TI [p = 0.03]), and increased ACD (p = 0.001).Conclusions and InferencesIBS‐C and FABD patients show reduced TI motility and differences in luminal content compared with HCs. This potentially indicates reflux of colonic contents or delayed clearance of the TI, which alongside increased ACD may contribute to symptoms of constipation and bloating.
Post‐transplant strategies to improve relapse‐free survival in childhood leukemia: Whole blood donor lymphocyte infusions and lenalidomide for inducing graft‐versus‐leukemia effect
Authors: Chandar Rumesh , Meena Satishkumar , Varla Harika , Ramakrishnan Balasubramaniam , Vellaichamy Swaminathan Venkateswaran , Uppuluri Ramya , Raj Revathi 
Published: April 2022

AbstractIntroductionPost‐transplant graft‐versus‐leukemia (GVL) effect has been shown to be an important determinant of a successful outcome following hematopoietic stem cell transplantation (HSCT) in children with acute leukemia.Patients and MethodsWe performed a retrospective analysis of the children up to 18 years of age with acute leukemia who underwent HSCT between November 2002 and November 2018. GVL induction strategies included whole blood donor lymphocyte infusions (DLI) and/or lenalidomide.ResultsA total of 134 children were included with engraftment in 125 children (93%). Acute graft‐versus‐host disease (GVHD) was documented in 85 (63%) children without any induction strategies. GVL induction strategies were employed in 19 children (14%); DLI (n = 12), Lenalidomide (n = 2), DLI + lenalidomide (n = 5). Among the 19, 12 children (63%) are alive without relapse; 6 children died of relapse (31%). Among the 6 who died of relapse despite induction strategies, 5/6 had ALL and one child had AML. GVL induction was effective in preventing relapse in 7/12 (58%) children with ALL and 5/6 (83%) children with AML. Relapse‐free survival in the cohort is 73/134 (55%) with a median follow‐up of 32 months. GVHD of any grade was significantly associated with a lower risk of relapse (p = .008). Median survival time was 160.3 days (range 132–187) in those with chronic GVHD versus 88.3 days (range 68–107) in those without (p value = .004).ConclusionPre‐emptive whole blood DLIs in graded aliquots, and lenalidomide are important tools for post HSCT GVL induction, which significantly impacts relapse‐free survival in childhood leukemia.
Trends in survival, perinatal morbidities and two‐year neurodevelopmental outcomes in extremely low‐birthweight infants over four decades
Authors: Zayegh Amir M. , Doyle Lex W. , Boland Rosemarie A. , Mainzer Rheanna , Spittle Alicia J. , Roberts Gehan , Hickey Leah M. , Anderson Peter J. , Cheong Jeanie L. Y. ,   the Victorian Infant Collaborative Study Group
Published: April 2022

AbstractBackgroundAlthough outcomes for infants born extremely low birthweight (ELBW; <1000 g birthweight) have improved over time, it is important to document survival and morbidity changes following the advent of modern neonatal intensive care in the 1990s.ObjectiveTo describe trends in survival, perinatal outcomes and neurodevelopment to 2 years’ corrected age over time across six discrete geographic cohorts born ELBW between 1979 and 2017.MethodsAnalysis of data from discrete population‐based prospective cohort studies of all live births free of lethal anomalies with birthweight 500–999 g in the state of Victoria, Australia, over 6 eras: 1979–80, 1985–87, 1991–92, 1997, 2005 and 2016–17. Perinatal data collected included survival, duration and type of respiratory support, neonatal morbidities and two‐year neurodevelopmental outcomes.ResultsMore ELBW live births were inborn (born in a maternity hospital with a neonatal intensive care unit) over time (1979–80, 70%; 2016–17, 84%), and more were offered active care (1979–80, 58%; 2016–17, 90%). Survival to 2 years rose substantially, from 25% in 1979–80 to 80% in 2016–17. In survivors, rates of any assisted ventilation rose from 75% in 1979–80 to 99% in 2016–17. Cystic periventricular leukomalacia, severe retinopathy of prematurity and blindness improved across eras. Two‐year data were available for 95% (1054/1109) of survivors. Rates of cerebral palsy, deafness and major neurodevelopmental disability changed little over time. The annual numbers with major neurodevelopmental disability increased from 12.5 in 1979–80 to 30 in 2016–17, but annual numbers free of major disability increased much more, from 31 in 1979–80 to 147 in 2016–17.ConclusionsActive care and survival rates in ELBW children have increased dramatically since 1979 without large changes in neonatal morbidities. The numbers of survivors free of major neurodevelopmental disability have increased more over time than those with major disability.
Conflict and oppositions in the development of peri‐urban agriculture: The case of the Greater São Paulo region
Authors: Torre André , Fonseca Brenno 
Published: April 2022

AbstractOne of the main factors preventing food production in urban and peri‐urban areas is territorial opposition between different land uses. The aim of this article is to address the question of conflicts close to large urban centres, taking the example of the São Paulo Metropolitan Region (SPMR), a representative urban area, which includes both food issues of the cities: the still important presence of subsistence agriculture that serves to feed the local people and the development of much‐gentrified urban agriculture. Our study is based on expert interviews, an analysis of the regional daily press and a study of local information sites and blogs. First, we briefly depict peri‐urban agriculture and its main characteristics, and we stress the importance of land‐use occupation faced with competing uses. Then, we present our method of analysis and the main agricultural characteristics of the SPMR. The third part is devoted to a study of the local conflicts, their location, their link to agriculture and the consumption of agricultural soils and the typology of the opponents and supporters of this activity. Finally, we conclude with some lessons on the place of peri‐urban agriculture drawn from this experiment.