bluuebunny/crossref_metadata_2025_split huggingface dataset:
Threaded rods grouted in beech laminated veneer lumber
Authors: Wirries Jonas , Tsopjio Franck Y. T. , Vallée Till , Myslicki Sebastian 
Published: March 2022

AbstractGlued‐in rods are a class of adhesively bonded joints for timber engineering applications resulting in high‐strength and stiffness connections. However, the use of polymeric adhesives may lead to issues related if the temperatures exceed their glass transition temperature, restricting their performance under quasi‐static, or more critically, sustained loads. To overcome these, the substitution of polymeric adhesives by mineral high‐performance grout was investigated. It was found that primers have neither a significant effect on strength nor on the failure mode; threated wood surfaces, however, resulted in a significant improvement of the latter. Based thereupon, grouted‐in rods were manufactured. The best performance was achieved with a threaded wood surface, which achieved roughly 50% of the strength comparable adhesively bonded glued‐in rod's strength. While the obtained strength may seem quite low, it is important to remind that the latter will largely remain unaffected by temperature; accordingly, made at room temperature, the comparison between grouted and glued rods is in favor of adhesive bonding, it may well be different at elevated ones.
Formation Mechanism of a Nano‐Ring of Bismuth Cations and Mono‐Lacunary Keggin‐Type Phosphomolybdate
Authors: Martins Inês C. B. , Al‐Sabbagh Dominik , Bentrup Ursula , Marquardt Julien , Schmid Thomas , Scoppola Ernesto , Kraus Werner , Stawski Tomasz M. , Guilherme Buzanich Ana , Yusenko Kirill V. , Weidner Steffen , Emmerling Franziska 
Published: March 2022

AbstractA new hetero‐bimetallic polyoxometalate (POM) nano‐ring was synthesized in a one‐pot procedure. The structure consists of tetrameric units containing four bismuth‐substituted monolacunary Keggin anions including distorted [BiO8] cubes. The nano‐ring is formed via self‐assembly from metal precursors in aqueous acidic medium. The compound (NH4)16[(BiPMo11O39)4] ⋅ 22 H2O; (P4Bi4Mo44) was characterized by single‐crystal X‐ray diffraction, extended X‐ray absorption fine structure spectroscopy (EXAFS), Raman spectroscopy, matrix‐assisted laser desorption/ionisation‐time of flight mass spectrometry (MALDI‐TOF), and thermogravimetry/differential scanning calorimetry mass spectrometry (TG‐DSC‐MS). The formation of the nano‐ring in solution was studied by time‐resolved in situ small‐ and wide‐angle X‐ray scattering (SAXS/WAXS) and in situ EXAFS measurements at the Mo−K and the Bi−L3 edge indicating a two‐step process consisting of condensation of Mo‐anions and formation of Bi−Mo‐units followed by a rapid self‐assembly to yield the final tetrameric ring structure.
Vaccine‐preventable disease hospitalized patients with heart failure with reduced ejection fraction
Authors: Del Cid Fratti Juan , Salazar Miguel , Argueta‐Sosa Erwin E. 
Published: March 2022

AbstractBackgroundOver five million Americans suffer from heart failure (HF), and this is associated with multiple chronic comorbidities and recurrent decompensation. Currently, there is an increased incidence in vaccine‐preventable diseases (VPDs). We aim to investigate the impact of HF with reduced ejection fraction (HFrEF) in patients hospitalized with VPDs.HypothesisPatient with HFrEF are at higher risk for VPDs and they carry a higher risk for in‐hospital complications.MethodsRetrospective analysis from all hospital admissions from the 2016‐2018 National Inpatient Sample (NIS) using the ICD‐10CM codes for patients admitted with a primary diagnosis of VPDs with HFrEF and those without reduced ejection fraction. Outcomes evaluated were in‐hospital mortality, length of stay (LOS), healthcare utilization, frequency of admissions, and in‐hospital complications. Multivariate regression analysis was conducted to adjust for confounders.ResultsOut of 317 670 VPDs discharges, we identified 12 130 (3.8%) patients with HFrEF as a comorbidity. The most common admission diagnosis for VPDs was influenza virus (IV) infection (75.0% vs. 64.1%; p < .01), followed by pneumococcal pneumonia (PNA) (13% vs. 9.4%; p < .01). After adjusting for confounders, patients with HFrEF had higher odds of having diagnosis of IV (adjusted [aOR], 1.42; p < .01) and PNA (aOR, 1.27; p < .01). Patients with VPDs and HFrEF had significantly higher odds of mortality (aOR, 1.76; p < .01), LOS, respiratory failure requiring mechanical ventilation, and mechanical ventilation for less than 96 h.ConclusionInfluenza and PNA were the most common VPDs admitted to the hospital in patients with a concomitant diagnosis of HFrEF. They were associated with increased mortality and in‐hospital complications.
A Series of Thiadiazolyl‐Benzenesulfonamides Incorporating an Aromatic Tail as Isoform‐Selective, Potent Carbonic Anhydrase II/XII Inhibitors
Authors: Banoglu Erden , Ercanlı Taner , Gür Maz Tuğçe , Vullo Daniela , Bonardi Alessandro , Gratteri Paola , Supuran Claudiu T. 
Published: March 2022

AbstractWe describe the synthesis of a series of thiadiazolyl‐benzenesulfonamide derivatives carrying an aromatic tail linked by an amide linker (12–34), as human carbonic anhydrase (hCA) inhibitors. These thiadiazol derivatives were evaluated against four physiologically relevant CA isoforms (hCA I, II, IX, and XII), and demonstrated intriguing inhibitory activity against CA II with Ki values in the range of 2.4–31.6 nM. Besides hCA II, also hCA XII activity was potently inhibited by some of the derivatives (Ki=1.5–88.5 nM), producing dual inhibitors of both isoforms. Notably, compound 17 was the most potent dual CA II (Ki=3.1 nM) and XII (Ki=1.5 nM) inhibitor with a significant selectivity ratio over CA I and IX isoforms. In conclusion, although all compounds exhibited preferential activity towards hCA II, the nature of the substituents at the tail part of the main scaffold influenced the activity and selectivity toward other isoforms.
A novel 3D convolutional neural network model with supervised spectral regression for recognition of hyperspectral images of colored wool fiber
Authors: Qiu Kebin , Chen Weiguo , Shen Jiajia , Zhou Hua 
Published: March 2022

AbstractPrior knowledge of textile fiber colors in blends is useful for color recipe assessment. There have been various methods to improve the accuracy of color recognition from the dataset of colored textile fibers in recent years. However, numerical assessments based on spectral feature and color difference is insufficient, in which the accuracy of color recognition can be affected by morphology and the uneven coloration on a single fiber. This paper proposes a novel 3D convolutional neural network model (3D‐CNN) with supervised spectral regression for the color recognition of hyperspectral images (HSI) of colored textile fiber. The proposed method obtained spatial‐spectral features based on 3D‐CNN, and the true spectrum of each class was used for supervised spectral regression to improve the accuracy. The loss function used was the sum of the supervised classification loss function and the spectral regression loss function model are optimized by mini‐batch‐based backpropagation. The proposed method was trained and tested on the HSI dataset composed of 100 colors of wool fibers acquired through a microscopic hyperspectral imaging system at a ×3.375 optical magnification. The experimental results showed that the proposed method exhibited better performance compared to numerical assessments and other deep learning models, except for efficiency. Specifically, it achieved better recognition performance on sub‐datasets of similar colored and light‐colored wool fiber where subtle inter‐class and large intra‐class variance existed.
Rbbp4 loss disrupts neural progenitor cell cycle regulation independent of Rb and leads to Tp53 acetylation and apoptosis
Authors: Schultz‐Rogers Laura E. , Thayer Michelle L. , Kambakam Sekhar , Wierson Wesley A. , Helmer Jordan A. , Wishman Mark D. , Wall Kristen A. , Greig Jessica L. , Forsman Jaimie L. , Puchhalapalli Kavya , Nair Siddharth , Weiss Trevor J. , Luiken Jon M. , Blackburn Patrick R. , Ekker Stephen C. , Kool Marcel , McGrail Maura 
Published: March 2022

AbstractBackgroundRetinoblastoma binding protein 4 (Rbbp4) is a component of transcription regulatory complexes that control cell cycle gene expression. Previous work indicated that Rbbp4 cooperates with the Rb tumor suppressor to block cell cycle entry. Here, we use genetic analysis to examine the interactions of Rbbp4, Rb, and Tp53 in zebrafish neural progenitor cell cycle regulation and survival.ResultsRbbp4 is upregulated across the spectrum of human embryonal and glial brain cancers. Transgenic rescue of rbbp4 mutant embryos shows Rbbp4 is essential for zebrafish neurogenesis. Rbbp4 loss leads to apoptosis and γ‐H2AX in the developing brain that is suppressed by tp53 knockdown or maternal zygotic deletion. Mutant retinal neural precursors accumulate in M phase and fail to initiate G0 gene expression. rbbp4; rb1 mutants show an additive effect on the number of M phase cells. In rbbp4 mutants, Tp53 acetylation is detected; however, Rbbp4 overexpression did not rescue DNA damage‐induced apoptosis.ConclusionRbbp4 is necessary for neural progenitor cell cycle progression and initiation of G0 independent of Rb. Tp53‐dependent apoptosis in the absence of Rbpb4 correlates with Tp53 acetylation. Together these results suggest that Rbbp4 is required for cell cycle exit and contributes to neural progenitor survival through the regulation of Tp53 acetylation.
Asset management optimization in smart grids
Authors: Dashti Reza , Hosseini Amirpouya 
Published: March 2022

AbstractElectricity distribution companies manage financial resources to maximize profits. While the stability of the electricity distribution system depends on the efficiency of the resources used by this system. The regulator is responsible for balancing and aligning the stability of the electricity industry with the profits of electricity distribution companies, which does so by adjusting penalty indices and service rates. This article investigates the management indicators of the electricity distribution industry and how to spend each of them is studied by electricity distribution companies and provides a model that can guide the optimization of the division of financial resources and investment between the indicators. Adjust indicators for regulators to align the benefits and profits of electricity distribution companies with the stability of the electricity distribution system. The implementation of this model was observed in Bushehr Electricity Distribution Company and increased the efficiency percentage.
Effects of antioxidant additive and injector hole number on combustion phenomenon of DI diesel engine operating with kapok methyl ester blends
Authors: Subramanian Narayanan , Kasimani Ramesh 
Published: March 2022

AbstractAlternate fuel research is aimed at improving the eminence of combustion behavior. This result focusses on the effects of injector hole number and antioxidant additives on combustion properties of diesel engine fueled with kapok methyl ester blends. Forty percent blend of kapok methyl ester was examined with a single cylinder diesel engine. The parameters of combustion such as peak pressure, net heat release, mean gas temperature were recorded and the influence of nozzle hole number and additives on the above said properties were thoroughly analyzed. From the experimental results it is evident that 6 hole nozzle along with B40 blended with 1000 ppm of tertiary butyl hydro quinone produced highest heat release rate of 102 J/°CA. Propyl gallate exhibited its lowest BSFC of 0.269 kg/kW h with B40 blend at minimum load.
Risk of variceal hemorrhage and pretransplant mortality in children with biliary atresia
Authors: Bass Lee M. , Ye Wen , Hawthorne Kieran , Leung Daniel H. , Murray Karen F. , Molleston Jean P. , Romero Rene , Karpen Saul , Rosenthal Philip , Loomes Kathleen M. , Wang Kasper S. , Squires Robert H. , Miethke Alexander , Ng Vicky L. , Horslen Simon , Kyle Jensen M. , Sokol Ronald J. , Magee John C. , Shneider Benjamin L. ,   ChiLDReN
Published: March 2022

Abstract

Background and Aims
The natural history of gastroesophageal variceal hemorrhage (VH) in biliary atresia (BA) is not well characterized. We analyzed risk factors, incidence, and outcomes of VH in a longitudinal multicenter study.

Approach and Results
Participants enrolled in either an incident (Prospective Database of Infants with Cholestasis [PROBE]) or prevalent (Biliary Atresia Study of Infants and Children [BASIC]) cohort of BA were included. Variceal hemorrhage (VH) was defined based on gastrointestinal bleeding in the presence of varices accompanied by endoscopic or nontransplant surgical intervention. Cumulative incidence of VH and transplant‐free survival was compared based on features of portal hypertension (e.g., splenomegaly, thrombocytopenia) and clinical parameters at baseline in each cohort (PROBE: 1.5 to 4.5 months after hepatoportoenterostomy [HPE]; BASIC: at enrollment > 3 years of age). Analyses were conducted on 869 children with BA enrolled between June 2004 and December 2020 (521 in PROBE [262 (51%) with a functioning HPE] and 348 in BASIC). The overall incidence of first observed VH at 5 years was 9.4% (95% CI: 7.0–12.4) in PROBE and 8.0% (5.2–11.5) in BASIC. Features of portal hypertension, platelet count, total bilirubin, aspartate aminotransferase (AST), albumin, and AST‐to‐platelet ratio index at baseline were associated with an increased risk of subsequent VH in both cohorts. Transplant‐free survival at 5 years was 45.1% (40.5–49.6) in PROBE and 79.2% (74.1–83.4) in BASIC. Two (2.5%) of 80 participants who had VH died, whereas 10 (12.5%) underwent transplant within 6 weeks of VH.

Conclusions
The low risk of VH and associated mortality in children with BA needs to be considered in decisions related to screening for varices and primary prophylaxis of VH.
Investigating thermal environment inside the kitchen of air‐conditioned pantry car on Indian Railway using CFD
Authors: Alam Md Sarfaraz , Sharma Milap , Salve Urmi R. 
Published: March 2022

AbstractIn an indoor kitchen environment, proper installation of supplying air system is essential for maintaining optimal human thermal comfort level. Current thermal comfort investigation has been accomplished during “various cooking periods (breakfast, lunch, snacks, dinner)” inside the air‐conditioned kitchen environment of railway pantry car in India. The study goals to improve thermal comfort inside the pantry kitchen by implementing proper installation of the supply air system. A field experiment and computational fluid dynamics approach has been carried out during the summer season. Also, standard effective temperature (SET) index was utilized to determine the thermal comfort status. Three proposed design modified cases of pantry cars (based on supplying air system concepts) have been executed followed by validation and comparison with the existing case model. Results revealed modified Case III as a better design concept (indicating better air supply circulation and temperature decrease at the desired location) compared to the existing and other two proposed cases. Simultaneously, the SET index range was 26.5–28.6°C; indicating “comfortable thermal sensation throughout the cooking period.” This study's outcomes suggest improvements in thermal comfort and energy savings of “air‐conditioned” pantry car kitchens in “Indian Railways” that could be referred directly.
The peak–end rule in evaluating product user experience: The chronological evaluation of past impressive episodes on overall satisfaction
Authors: Doi Toshihisa , Doi Sayoko , Yamaoka Toshiki 
Published: March 2022

AbstractThis study investigates the peak–end rule's applicability in evaluating the product user experience in the context of overall satisfaction with smartphone applications, a chronological evaluation of past impressive episodes with the use of applications, and the satisfaction level of each episode. The effects of the positive and negative peaks (maximum and minimum satisfaction score) and the end (satisfaction score at the most recent episode) were analyzed against the overall satisfaction in a series of episodes. Two representative groups (satisfied and dissatisfied) were surveyed regarding their satisfaction with a selected application. A correlation analysis between the variables revealed that the peaks and the end correlated with overall satisfaction. Further analysis with hierarchical multiple regression models revealed that the positive and negative peaks do not necessarily explain overall satisfaction dominantly in the regression model of this study. However, the possibility that they are related to the overall satisfaction was confirmed. In contrast, this study demonstrated the significant influence of the most recent event on the overall satisfaction level.
Association of maternal hemoglobin levels during pregnancy with sleep and developmental problems in 1‐year‐old infants: A cohort study
Authors: Nakahara Kazushige , Michikawa Takehiro , Morokuma Seiichi , Hamada Norio , Ogawa Masanobu , Kato Kiyoko , Sanefuji Masafumi , Shibata Eiji , Tsuji Mayumi , Shimono Masayuki , Kawamoto Toshihiro , Ohga Shouichi , Kusuhara Koichi ,   The Japan Environment and Children's Study Group
Published: March 2022

AbstractBackground and AimsMaternal hemoglobin concentration during pregnancy is reported to be associated with various perinatal outcomes and may also be associated with infant development. This study aims to investigate the association between maternal hemoglobin levels during early or mid‐pregnancy and sleep and developmental problems in 1‐year‐old infants.MethodsWe used the data of 66,935 pregnant women who were participants of the Japan Environment and Children's Study, a nationwide cohort study in Japan, between 2011 and 2014. Maternal hemoglobin level was examined at recruitment (mean gestational age, 15.3 weeks; SD, 2.85 weeks; range, 6–22 weeks). Information on infant sleep and development at the age of 1 year was acquired using a questionnaire. Infant development was evaluated using the Ages and Stages Questionnaire (ASQ).ResultsThe mean (SD) maternal hemoglobin level was 12.0 (1.0) g/dl. Maternal hemoglobin levels were not associated with the majority of infant sleep and developmental outcomes. In the group with maternal hemoglobin <10.0 g/dl, the risk ratio (RR) for sleep at 22:00 or later was higher than that in the reference group with 11.0 g/dl ≤ hemoglobin < 14.0 g/dl (RR 1.12, 95% confidence interval = 1.00–1.25). In the analysis with maternal hemoglobin level as a continuous variable, both high and low hemoglobin levels were associated with a higher RR of a late bedtime. In addition, a low maternal hemoglobin level was associated with a higher RR for abnormal fine motor skills in the ASQ.ConclusionOur results suggest that a low level of maternal hemoglobin during pregnancy is associated with late bedtime and abnormal fine motor skills in 1‐year‐old infants. Conversely, a high level of maternal hemoglobin may also be associated with the infant's late bedtime.
Thermophoretic movement, heat source, and sink influence on the Williamson fluid past a Riga surface with positive and negative Soret‐Dufour mechanism
Authors: Akolade Mojeed T. , Oyekunle Timothy L. , Momoh Hafizat O. , Awad Mohamed M. 
Published: March 2022

AbstractThis study investigates the boundary layer motion of Williamson fluid over an electromagnetic with thermophoretic movement, variable thermal conductivity and viscosity, nonlinear radiation, and Soret‐Dufour influences. The real prediction of regional movement and temperature‐dependent properties of the non‐Newtonian fluids in real space (three‐dimensional [3D]) becomes imperative due to their numerous industrial, engineering, and biomedical use. This flow motion is induced as a result of the introduced mechanism (Riga plate) capable of controlling a weakly hydromagnetic flow. To actualize the aim of this study, the formulated governing partial differential equations conveying the flow model of Williamson fluid in a 3D sense are transformed to systems of ordinary differential equations (ODEs) via applicable similarity variables. The reduced systems of ODEs are solved numerically by the collocation approach. Therein, the Riga surface is seen preventing the heat source/sink impact on the flow fields, the thermophoretic impact indicates a more accumulation of Williamson fluid particles in the cold region thus resulting in higher fluid concentration. Thermal variability energizes the energy field positively, momentum boundary layer reduction prevails for higher Williamson number while heat source dominates the temperature field and heat sink showcases its ability to enhance the fluid concentration in contrast to the heat source.
Tests of bidirectional relations of TV exposure and effortful control as predictors of adjustment in early childhood in the context of family risk factors
Authors: Parrish Krystal H. , Smith Michele R. , Moran Lyndsey , Ruberry Erika J. , Lengua Liliana J. 
Published: March 2022

AbstractThis study examined bidirectional relations between television exposure and effortful control accounting for the effects of family contextual risk factors. Data were from a sample (N = 306) of parents and their preschool‐age children (T1 M = 36 mos. in 2008–2010) assessed four times, once every 9 mos. At T1, adolescent parent status predicted lower child delay ability (DA), and maternal depression predicted higher TV time. Above these effects, higher T1 and T2 child executive control (EC) prospectively predicted lower T2 and T3 TV time, while higher T1 TV time predicted lower T2 EC. Higher EC at T4 predicted fewer total problems, greater social competence, and greater academic readiness at T4, and higher TV time at T4 predicted lower academic readiness. DA was unrelated to TV time or adjustment. Findings suggest executive control and TV time predict changes in each other in early childhood, and in turn, executive control predicts better child adjustment while TV time might be more relevant for academic readiness. Moreover, family risk factors appear to play a role in both TV viewing time and effortful control.