bluuebunny/crossref_metadata_2025_split huggingface dataset:
Measuring the Relative Importance of Fiscal and Monetary Policy in Stimulating Economic Growth in Yemen: An Econometrics Study Using Co-integration Approach
Authors: Al-Hawri Prof. Dr. Mohammed Ahmed 
Published: July 2022

The study attempted to analyze and evaluate the performance of monetary and fiscal policy for the period 2000-2014 and its effectiveness in increasing economic growth using the descriptive analytical and econometrics approach. The study also attempted to measure the relative importance of fiscal and monetary policies and their relationship to economic growth using the co-integration method and the error correction model, which allows measuring the relative importance of fiscal and monetary policy and its relation to economic activity. Analysis of fiscal and monetary indicators showed that there were imbalances and distortions in financial and monetary performance that contributed to the weak effectiveness of fiscal and monetary policy in achieving economic stability and stimulating economic growth.
Keywords: co-integration method, fiscal policy, monetary policy, economic growth, error correction model.
Impact of Effectiveness and Efficiency of Internal Audit on Improving Financial Performance: A Field Study in Banks Operating in Yemen
Authors: Al-Sorihi Dr. Sultan Ali Ahmed , Al-Salafi Hamid Sa'ad Mohsen 
Published: July 2022

This study aimed to examine the impact of the efficiency and effectiveness of internal audit in improving financial performance on banks operating in Yemen. To achieve this objective, a questionnaire was used to collect data from the population, where 216 questionnaires were distributed to a sample of board members, audit committees, internal audit and financial management of banks. After colecting the data, the statistical multiple regression analysis was used to test the hypotheses of the study. The study findings revealed a high positive impact of the effectiveness and efficiency of internal audit on improving financial performance in banks. The findings also showed that the impact of effectiveness of internal audit was higher than that of its efficiency. Based on these results, it was recommended to pay attention to the effectiveness of internal audit, including its dimensions: (purpose, authority and responsibility) and (independence and objectivity). Attention should also be paid to the efficiency of internal auditing, including its dimensions: (professional diligince and skills) and (quality improvement program). It was also recommended to implement the recommendations of the bank internal auditors who should be independent and directly affiliated to the senior management and the audit committee.
Keywords: banks operating in Yemen, improving financial performance, effectiveness and efficiency of internal audit.
The Effect of Transformational Leadership on Administrative Empowerment: A Field Study at Pharmaceutical Manufacturers in Yemen
Authors: Prof. Dr. Abdullatif Musleh Mohammed Ayedh  , Dr. Abdulkarem Saleh Hussein Al-Qahfa  
Published: July 2022

The study aimed to measure the impact of transformational leadership on administrative empowerment, and identify the level of practicing it at pharmaceutical manufacturers in Yemen. It also aimed to identify the level of administrative empowerment practice in these companies. To achieve the objectives of the study, the descriptive and analytical method was adopted, and a questionnaire was distributed to a sample of 330 participants selected by the complete sensus sampling method. However, only 227 of the questionnaires were valid for analysis. For data analysis, many descriptive and inferential statistical methods were used. Findings revealed that the level of practicing transformational leadership did not reach the expected level, as the mean was just medium. There were differences at the level of practicing the dimensions of transformational leadership; the highest effective difference was the intellectual arousal and the least one was the individualized consideration. Findings also showed that the level of administrative empowerment practice was medium, and the practice level of the dimension of authority delegation was high while participation in decision-making was low. Moreover, there were differences at the level of the impact of the dimensions of transformational leadership on administrative empowerment; the highest effective difference was the ideal effect and the least one was the individualized consideration. The study stressed the need to adopt various dimensions of transformational leadership, at pharmaceutical manufacturers in Yemen, with an emphasis on individualized consideration as this can have a great impact on administrative empowerment.
Keywords: administrative empowerment, pharmaceutical manufacturers in Yemen, transformational leadership
Publication ethics of human studies in the light of the Declaration of Helsinki – a mini-review
Authors: Sawicka-Gutaj Nadia , Gruszczyński Dawid , Guzik Przemysław , Mostowska Adrianna , Walkowiak Jarosław 
Published: July 2022

The Declaration of Helsinki is a set of ethical principles to be followed by scientists involved in medical research with humans or human cells and tissues. This Declaration defines how scientific research should be planned, carried out, documented, analysed, and published.
We summarise and discuss some ethical issues related to publishing original articles, including clinical trials, review papers, and case reports based on the seventh revision of the Declaration of Helsinki.
The principles of the Declaration of Helsinki refer most strongly to the publication of medical research results, in particular clinical trials, as original articles. Such papers must meet several ethical requirements, especially the study protocol transparency and the presentation of the results. For case reports, the bioethical aspects related to their publication are twofold - they must include informed and voluntary consent and the confidentiality of study participants. The review papers are of the least bioethical concern. However, whether patients' agreements with specific studies are valid if the data are used in meta-analyses is uncertain.
Adherence to ethical policies and standards helps to ensure the highest possible quality of scientific publications. Responsibility for compliance with the Declaration of Helsinki lies not only with the authors preparing their manuscripts but also with the editorial board and reviewers, who must evaluate the ethical soundness of the submitted papers. The additional guidelines for the different types of studies facilitate the implementation of the Declaration principles.
Transient and Steady-State Aspects of Gas Condensate Well Performance
Authors: Chopra Anil K. 
Published: July 2022

Abstract
Several important reservoir engineering aspects of gas condensate well performance are investigated using an IMPES (Implicit Pressure Explicit Saturation) compositional simulator which employs a modified Redlich Kwong Equation of State to describe phase equilibria. These aspects are: total hydrocarbon fluid production rate, saturation and pressure profiles, gas-oil ratio and produced fluid compositions. The simulations are performed using a gas condensate fluid from a reservoir in the Overthrust Belt. The initial condition is a constant reservoir pressure. Simulations include transient state when two-phase flow occurs and steady-state when the flowing phase composition becomes constant. Both radial and linear systems are examined.
Excellent agreement between the results of the compositional simulator at steady-state/near steady-state conditions and the two-phase steady-state theory (Chopra and Carter1) is obtained. A step-by-step procedure to compute performance of gas condensate wells using the two-phase steady-state theory is illustrated. It is shown that the two-phase steady-state theory is a satisfactory approach for predicting the performance of gas condensate wells once the criteria for steady-state are satisfied. The conventional criteria to determine when steady-state is achieved for single phase systems are not applicable to two-phase gas condensate systems. Based on a study of the produced fluid compositions and the areal extent of the two-phase region, criteria for steady-state are suggested. A compositional simulator is needed to model transient conditions. The valuable applications of the two-phase steady-state theory are to validate a simulator and evolve new techniques for two-phase pressure transient analysis techniques.
Dual-Targeted Near-Infrared Photoimmunotherapy for Esophageal Cancer and Cancer-Associated Fibroblasts in the Tumor Microenvironment
Authors: Sato Hiroaki , Noma Kazuhiro , Ohara Toshiaki , Kawasaki Kento , Akai Masaaki , Kobayashi Teruki , Nishiwaki Noriyuki , Narusaka Toru , Komoto Satoshi , Kashima Hajime , Katsura Yuki , Kato Takuya , Kikuchi Satoru , Tazawa Hiroshi , Kagawa Shunsuke , Shirakawa Yasuhiro , Kobayashi Hisataka , Fujiwara Toshiyoshi 
Published: July 2022

Abstract
Cancer-associated fibroblasts (CAFs) play a significant role in tumor progression within the tumor microenvironment. Previously, we used near-infrared photoimmunotherapy (NIR-PIT), a next-generation cancer cell-targeted phototherapy, to establish CAF-targeted NIR-PIT. In this study, we investigated whether dual-targeted NIR-PIT, targeting cancer cells and CAFs, could be a therapeutic strategy. A total of 132 cases of esophageal cancer were analyzed for epidermal growth factor receptor (EGFR), human epidermal growth factor 2 (HER2), and fibroblast activation protein (FAP) expression using immunohistochemistry. Human esophageal cancer cells and CAFs were co-cultured and treated with single- or dual-targeted NIR-PIT in vitro. These cells were co-inoculated into BALB/c-nu/nu mice and the tumors were treated with single-targeted NIR-PIT or dual-targeted NIR-PIT in vivo. Survival analysis showed FAP- or EGFR-high patients had worse survival than patients with low expression of FAP or EGFR (log-rank, p < 0.001 and p = 0.074, respectively), while no difference was observed in HER2 status. In vitro, dual (EGFR/FAP)-targeted NIR-PIT induced specific therapeutic effects in cancer cells and CAFs along with suppressing tumor growth in vivo, whereas single-targeted NIR-PIT did not show any significance. Moreover, these experiments demonstrated that dual-targeted NIR-PIT could treat cancer cells and CAFs simultaneously with a single NIR light irradiation. We demonstrated the relationship between EGFR/FAP expression and prognosis of patients with esophageal cancer and the stronger therapeutic effect of dual-targeted NIR-PIT than single-targeted NIR-PIT in experimental models. Thus, dual-target NIR-PIT might be a promising therapeutic strategy for cancer treatment.
Unrelated umbilical cord blood can improve the prognosis of haploidentical hematopoietic stem cell transplantation
Authors: Yang Ying , Zhang Ming , Li Mengqi , Li Yingchun , Yang Wei , Liu Zhuogang , Wang Hongtao 
Published: July 2022

Abstract
Background :Haploidentical hematopoietic stem cell transplantation (haplo-HSCT) is widely used as a curative treatment strategy for most types of hematological diseases. However, strategies for enhancing the graft versus leukemia (GVL) effect without aggravating the graft versus host disease (GVHD) effect are still being pursued.Methods: A retrospective cohort study was performed to compare the outcomes between combined unrelated umbilical cord blood (UCB-haplo HSCT) and haplo HSCT.Results: The results showed that neither aGVHD nor cGVHD was increased in the UCB-haplo HSCT group, and the engraftment and infection rates were similar between the two groups. However, overall survival (OS) and progression-free survival (PFS) were significantly improved, while transplantation-related mortality (TRM) and relapse were significantly decreased in the UCB-haplo HSCT group by both univariate and multivariate analyses.Conclusion: Our results indicated that the addition of a UCB unit could improve the prognosis of haplo-HSCT and enhance the GVL effect without increasing the incidence of GVHD. Trial registration: The cohort study was retrospectively registered at https://www.chictr.org.cn as ChiCTR2100046681.
Mycobacterium Effects of Traits for Microscopy
Authors: Ubani Solomon 
Published: July 2022

Abstract
Research was to study mycobacterium a species of pathogenic bacteria. The research question was impervious to Gram staining resultant of either negative or positive effects. The method involve studies of mycobacterium an etiologic parasite. These were 2 to 4 micrometers in length and 0.2 to 0.5µm in width. The results showed the bacteria settlement in the cytoplasm of the plants and growth. This suggested it can be transferred to other eukaryotes. Plants were immunoprevention treatment 15mL each day for a month. Eukaryotic with possibility of mycobacterium should be considered for treatment at least 15mm of induration or had a Gram-positive result. It concluded the treatment had streptomycin production a synthesis inhibitor. It combined to small 16S rRNA of the 30S subunit prevention of binds of formyl-methinonyl-tRNA to the sequence.
Impact of COVID-19 pandemic on the mental health of university students in the United Arab Emirates: a cross-sectional study
Authors: Misra Anamika V. , Mamdouh Heba M. , Dani Anita , Mitchell Vivienne , Hussain Hamid Y. , Ibrahim Gamal M. , Dalky Heyam F. , Alnakhi Wafa K. 
Published: July 2022

Abstract
Background: The COVID-19 pandemic had a significant impact on the mental well-being of students worldwide. There is a scarcity of information on the mental health impact of the COVID-19 pandemic on university students in the United Arab Emirates (UAE). This study aimed to investigate the mental health impact of the COVID-19, including depression, anxiety and resilience among a sample of university students in the UAE. Methods: A cross-sectional study using an online survey was conducted from September to November 2021. The patient health questionnaire (PHQ-9), generalized anxiety disorder-7 (GAD-7) and Connor–Davidson Resilience Scale (CD-RISC-10) were used to assess depression, anxiety, and resilience. The COVID-19 impact was assessed using a list of questions. Results: Only, 798 students completed the survey and were analyzed for this study. Overall, 74.8% of the students were females, 91.2% were never married, and 66.3% were UAE-nationals. Based on PHQ-9 and GAD-7 cut-off scores (≥ 10), four out of ten of the students self-reported moderate and severe depression (40.9%) and anxiety (39.1%). Significantly higher mean PHQ-9 and GAD-7 scores were found among students who were impacted by COVID-19 than those non-impacted (mean PHQ-9 of 9.51± 6.39 and 6.80 ±6.34; p= 0.001, respectively) and (mean GAD-7 of 9.03 ±6.00 and 8.54 ±6.02; respectively, p < 0.001). Female students who were impacted by COVID-19 had statistically significant higher depression and anxiety scores than the non-impacted females (mean PHQ-9 of 9.14 ±5.86 versus 6.83 ±6.25, respectively; p<0.001 and mean GAD-7 of 9.57 ±6.32 versus 5.15 ±3.88, respectively; p= 0.005). Never married students had significantly higher PHQ-9 and GAD-7 scores than ever-married (9.31 ± 6.37 versus 6.93 ± 5.47, P=0.003) and (8.89 ± 6.11 versus 7.13 ± 5.49, respectively; p=0.017). Only one in ten of the students revealed high resilience levels, however, differences in the mean CD-RISC-10 scores by COVID-19 impact were not statistically significant. Conclusions: The results of this study demonstrate that the COVID-19 pandemic has negatively impacted the mental health of this sample of university students in terms of depression and anxiety. The results highlight the need to adopt culturally appropriate interventions for university students and focus on vulnerable groups.
Ventriculoperitoneal shunt versus endoscopic third ventriculostomy for post-thalamic hemorrhage hydrocephalus
Authors: Chen Bin , Lu Wenchao , Feng Kang , Xu Jun , Jia Dong 
Published: July 2022

Abstract
Objective: To compare the efficacy of ventriculoperitoneal shunt (VPS) and endoscopic third ventriculostomy (ETV) in the treatment of hydrocephalus after thalamic hemorrhage (TH), so as to provide reasonable surgical treatment.Methods: The clinical data of 87 patients with hydrocephalus after TH admitted to our hospital were retrospectively analyzed. The patients were divided into VPS group and ETV group according to different surgical methods. The operation time, hospital stay, complications and reoperation rate of the two groups were compared.Results: There was no statistical difference in intraoperative bleeding and length of hospital stay between the two groups, and all patients had external ventricular drainage. (EVD) removed successfully after surgery. 7 (16.6%) complications in the ETV group and 5 (11.0%) complications in the VPS group. There was no significant difference in postoperative complications between the two groups. 10 cases (26.2%) in the ETV group required reoperation and 4 cases (8.9%) in the VPS group required reoperation. There was significant difference in reoperation rate between the two groups. In subgroup analysis, TH with fourth ventricular hemorrhage, 7 cases (16.7%) required reoperation in the ETV and 1 case (2.2%) required reoperation in the VPS group. The difference between the two groups was statistically significant.Conclusion: Both ETV and VPS have good efficacy in treating hydrocephalus caused by TH and TH breaking into the lateral ventricle and the third ventricle, and the EVD can be successfully removed after surgery. However, if the hydrocephalus caused by TH with fourth ventricular hematoma, the reoperation rate of ETV is higher, and such patients are more suitable for VPS. Therefore, the choice of surgical methods should be adopted based on the patient's clinical manifestations, hematoma type.
A drug free solution for improving the quality of life of fibromyalgia patients (Fibrepik): study protocol of a multicenter, randomized, controlled effectiveness trial.
Authors: CHIPON Emilie , BOSSON Jean-Luc , MINIER Laure , DUMOLARD Anne , VILOTITCH Antoine , CROUZIER David , MAINDET Caroline 
Published: July 2022

Abstract
Background: Fibromyalgia is a form of chronic widespread pain that is defined as a syndrome of chronic symptoms of moderate to severe intensity, including diffuse pain, fatigue, sleep disturbance, cognitive impairment, and numerous somatic complaints. To date, there is no specific drug treatment for fibromyalgia but only symptomatic treatments. A drug free solution based on a wristband which emits millimeter waves associated with a therapeutic coaching program was developed. The application of millimeter waves on an innervated area have been described to have a neuromodulating effect, due to endorphin release stimulation and parasympathetic activation. Coaching is carried out to improve patient’s adherence and to increase compliance and effectiveness of the treatment. Regular use of this solution by fibromyalgia patients is expected to improve sleep quality, reduce anxiety and pain level, and at the end, increase the quality of life.Methods: This trial is performed over 8 French inclusion centers for a total of 170 patients. The effectiveness of the solution is evaluated according to the primary objective, the improvement of the quality of life measured through the dedicated Fibromyalgia Impact Questionnaire after 3 months. Patients are randomized in two groups, Immediate or Delayed. The Immediate group has access to the solution just after randomisation in addition to standard care, while Delayed has access to the standard of care and wait for 3 months to have the solution. The purpose of this methodology is to limit deception bias and facilitate inclusion. The solution consists in using the device for three sessions of 30 minutes per day and four coaching sessions spread over the first two months of wristband usage.Discussion: The objective is to confirm the effect of the integrative approach based on endorphin stimulation and a therapeutic coaching program in nociplastic pain, and specifically for patient suffering from fibromyalgia. If the effectiveness of the solution is demonstrated, we will be able to respond to the demand of fibromyalgia patients for access to an effective non-medicinal treatment to improve their quality of life.Trial registration: ClinicalTrials.gov NCT05058092
Turmeric Powder Supplementation in Broiler Diet Improves Growth Performance and Immunity via Increasing mRNA Expression of Growth Hormone, Insulin Like Growth Factor-1, Interferon Gamma and Interleukin12
Authors: Shawky Sherif , Fathalla Said , Orabi Sahar , El-Mosalhi Huda , Abu-Alya Ibrahim 
Published: July 2022

Abstract
Background
The research was carried out to assess how adding turmeric powder to the diet affected Cobb broiler chickens' productivity and immunity. A total of 150 broiler chicks were divided into two groups with 3 replicates of 25 birds each. The control group was given the basal diet. The Turmeric group was given turmeric in a dose of 5g/Kg ration.
Results
Statistical analysis showed that turmeric powder significantly improved final body weight (FW), weight gain (WG), and feed conversion ratio (FCR), IgM, IgG, globulins (alpha 1 globulin and gamma globulin) in serum. In addition, turmeric significantly increases mRNA expression of growth hormone (GH), insulin-like growth factor-1 (IGF-1), interferon-gamma (INF-γ), and Interleukin 12 (IL-12p35) in comparison to the control group
Conclusion
The Turmeric powder added to the diet showed the best effects on productivity and immunological response.
Modified Emden type Oscillator Equations with Exact Harmonic Solutions
Authors: YESSOUFOU Akim Boukola , ADJAÏ Kolawolé Kêgnidé Damien , AKANDE Jean , MONSIA Marc Delphin 
Published: July 2022

Abstract
This paper is devoted to investigating the existence of exact harmonic solutions and limit cycles of certain modified Emden-type equations. The exact and general solutions obtained are in opposition to the predictions of classic existence theorems.