bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychosoziales Screening in der Physiotherapie: Wo verläuft die Grenze zur Komorbidität?
Authors: Kalmring Matthias 
Published: July 2022

ZusammenfassungDie Behandlung von Patient*innen mit chronischen Schmerzen stellt sich häufig als sehr komplex dar und benötigt oft eine multimodale Therapiestrategie. Daher hat der Einbezug von psychosozialen Faktoren in die physiotherapeutische Therapieplanung und Behandlung bei Patient*innen mit chronischen muskuloskelettalen Schmerzen in den letzten Jahren immer mehr an Bedeutung gewonnen. Allerdings scheint es in der Physiotherapie eine Herausforderung darzustellen, psychosoziale Einflüsse zu erheben, zu interpretieren und aus ihnen therapeutische Konsequenzen zu ziehen.Dieser Fallbericht eines 44 Jahre alten Patienten mit Schulterschmerzen soll die Bedeutsamkeit eines standardisierten Screening Protokolls zur Bewertung von psychosozialen Einflussfaktoren bei Patient*innen mit chronischen muskuloskelettalen Beschwerden aufzeigen. Die Ergebnisse aus der Herzratenvariabilitätsmessung und dem Fragebogen „Maslach Burnout Inventory“ deuteten auf eine erhöhte Belastung des Patienten durch psychosoziale Stressoren, die eine Burnout-Gefährdung anzeigten. Neben der schulterspezifischen funktionellen Physiotherapie wurden, in interdisziplinärer Absprache, die Erholungsfähigkeit und Stresskompensation des Patienten in der Therapie adressiert. Die mit diesen Maßnahmen ergänzte Physiotherapie konnte Verbesserungen auf der Funktions- und Schmerzebene erzielen.
Sonographic Comparison of Neck Extensor Muscle Thickness of
Ankylosing Spondylitis and Non-radiographic Axial Spondyloarthritis Patients
with Healthy Volunteers
Authors: Karabaş Çağlar , Aras Berke , Erol Kemal , Kuzu Ömer 
Published: July 2022

Abstract
Introduction This study examines the neck extensor muscle thickness of
patients with ankylosing spondylitis (AS) and non-radiographic axial
spondyloarthritis (nr-axSpA) by comparing them with healthy volunteers. It also
aims to evaluate the relationship between muscle thickness and disease activity,
functional parameters, neck disability and quality of life in patients with
AxSpA.
Method In this cross-sectional study, 30 patients with AS and 30 patients
with nr-AxSpA who were admitted to a Physical Medicine and Rehabilitation
outpatient clinic were included consecutively. Thirty healthy participants were
included as a control group. The thickness of muscles was measured bilaterally
by ultrasound and the muscle thickness average was recorded. All patients with
axSpA were asked to complete the Bath Ankylosing Spondylitis Disease Activity
Index (BASDAI), the Bath Ankylosing Spondylitis Functional Index (BASFI), the
Bath Ankylosing Spondylitis Metrology Index (BASMI), the Ankylosing spondylitis
Quality of Life (AsQoL) scale and the Neck Disability Index (NDI).
Results Mean patient age was 42.36±10.0 in the AS group,
38.13±7.94 in the nr-axSpA group and 39.06±8.25 in the healthy
group. A statistically significant decrease was found in multifidus,
semispinalis capitis, semispinalis cervicis and splenius capitis muscle
thickness in AS patients compared with the healthy group, and in semispinalis
cervicis muscle thickness in nr-axSpA patients compared with the healthy group.
However, when trapezius muscle thickness was compared between the groups, no
statistical difference was found. There was a significant negative correlation
between neck extensor muscle thickness and age, BASDAI, NDI and AsQoL in
patients with axSpA.
Conclusion The thickness of the neck extensor muscles is decreased in
patients with AxSpA compared with healthy individuals, and this situation can be
reliably detected by ultrasound.
Outcomes of Coverage of Soft Tissue Defects in the Thumb with a
“Kite Flap”
Authors: Zyluk Andrzej , Flicinski Filip 
Published: July 2022

AbstractDeep soft tissue injuries and defects in the digits such as pulp amputation and
degloving injuries are relatively frequent in hand surgical practice. Injuries
around the thumb constitute a specific subtype, because their fitting requires
the use of techniques that are different from standard. Many different surgical
options have been described for the treatment of these serious lesions,
depending on site and size of the defect, as well as on bone exposition. The
“kite flap” is one of the most popular and frequently used.
Results of the treatment of 14 of the 22 patients whose defects in the thumb
were fitted with the kite flap are presented. The flaps healed in all patients.
At the mean follow-up of 3 years all patients declared satisfaction with the
result of surgery. Most of them had slightly limited mobility of the operated
thumbs but with no significant translation to the function of the hands, which
was very good. The results of this study show that the kite flap is useful in
reconstruction of soft tissue defects around the thumb, which are difficult to
cover by more conventional techniques
Functionalization of Alkyl Groups Adjacent to Azoles: Application to the Synthesis of α-Functionalized Carboxylic Acids
Authors: Bhadra Sukalyan , Singh Anupam Kumar , Shinde Rupali Dasharath , Kumar Jogendra 
Published: July 2022

AbstractA plethora of bioactive compounds and natural products bears an azole subunit within their complex structural frameworks. A footstep to realize those complex structures in atom economic fashion rely on the direct functionalization of C–H bonds adjacent to an azole group. In addition, the resulting functionalized azole compounds can be simply modified into practically significant genre of α-functionalized carboxylic acids that are otherwise inaccessible through a formal α-functionalization strategy. In this Account, we describe an up-to-date progress on the functionalization of a methyl and/or methylene group(s) adjacent to an azole ring enabled by late and earth-abundant transition metals. Contributions made by our group and that by others in the field are elaborated in this Account article.1	Introduction2	Mode of Reactivity of C–H Bonds Next to Azoles under Transition-Metal Catalysis3	Pd-Catalyzed Functionalization of Alkyl Groups Adjacent to an Azole Ring3.1	Functionalization through C–C Bond Formation3.2	Functionalization through C–Heteroatom Bond Formation4	3d-Metal-Catalyzed Functionalization of Alkyl Groups Adjacent to an Azole Ring5	Other Metal-Catalyzed Functionalization of Alkyl Groups Adjacent to an Azole Ring6	Conclusion and Future Prospects
Complex Bench Surgery Does Not Increase the Risk of Vascular Complications after Pediatric Kidney Transplantation
Authors: Ghidini Filippo , Fascetti Leon Francesco , De Corti Federica , Meneghesso Davide , Longo Germana , Sgrò Alberto , Michelon Stefania , Metrangolo Salvatore , Meneghini Luisa , Castagnetti Marco , Benetti Elisa , Gamba Piergiorgio , Dall'Igna Patrizia 
Published: July 2022

AbstractIntroduction Vascular complications are severe complications of pediatric kidney transplantation (KT). We aimed to investigate whether a complex bench surgery (BS) affects the outcomes.Methods All pediatric KT performed at the University Hospital of Padua from 2015 to 2019 were analyzed, comparing those in which a standard BS was possible to those that necessitated a complex BS. The rates of vascular complications, patients' outcome, and graft survival were compared in the two groups.Results Eighty KTs were performed in 78 patients with a median age of 11 years (interquartile range [IQR] 4.3–14) and a median body weight of 24 kg (IQR 13–37). Thirty-nine donor kidneys (49%) needed a complex BS due to anomalies of renal veins in 12 (31%) and renal arteries in 16 (41%). The remaining 11 grafts (28%) underwent an elongation of the vein. There was no difference in the rate of primary graft non function (p = 0.97), delayed graft function (p = 0.72), and overall survival (p = 0.27). The rates of vascular complications, bleedings, and venous graft thrombosis were similar (p = 0.51, p = 0.59, p = 0.78, respectively). No arterial thrombosis or stenosis was reported.Conclusion Complex BS did not compromise survival of the graft and did not put the allograft at risk of vascular complications, such as bleedings or thrombosis.
Blue carbon sequestration following mangrove restoration: evidence from a carbon neutral case in China
Authors: Ratul Sourav Bagchi , Gu Xiaoxuan , Qiao Peiyang , Sagala Febrina Wulanda , Nan Shu , Islam Nazrul , Chen Luzhen 
Published: July 2022

ABSTRACT

Sequestration of blue carbon (C) in mangrove plantations depends on site characteristics and plantation management. This study evaluated the effects of plantation management on C sequestration at a C-neutral site in Xiamen, China. A field study was conducted on 10-year-old
Sonneratia apetala
and
Kandelia obovata
plantations (mono-Sa, mono-Ko) and a 15-year-old mixed plantation-. We found that mono-Ko had a significantly higher ecosystem C sequestration rate (3.32 ± 0.62 kg C m
−2
yr
−1
) than others when planted in the indirect shade of pioneer species. As a non-native species,
Sonneratia
performed better (0.57 ± 0.01 kg C m
−2
yr
−1
) when planted with
Kandelia
than in monotypic plantations. The temporary and long-term certified emission reduction (tCER and lCER) of the 12.98 ha mono-Ko was 4103.89 and 3693.50 net CO
2
-e within 10 years, respectively. A literature review was conducted to show the compatibility of this study with other natural and plantation sites of China and Bangladesh (the native habitat for
Sonneratia
). The C sequestration of
Sonneratia
plantation sites in China is comparable with those in Bangladesh. However, the soil C accumulation rate for a
Sonneratia
monotypic plantation in Bangladesh decreased with age, yet the same did not occur in the plantations of China.
Integration of PCM as an external wall layer in reducing excessive heat of building walls
Authors: Nor Ali Umi Nadiah , Mohamad Nor Norazman , Misnon Noor Aina , Mohd Noor Siti Aminah , Othman Maidiana , Alias Muhammad Akmal Akif , Syamsir Agusril 
Published: July 2022

Abstract
Innovative building approaches, which take advantage of heat energy in buildings, have recently appeared as part of a global effort to save energy. Incorporating phase change material (PCM) into the building envelope helps in reducing energy consumption and regulating energy demand by managing the thermal inertia of designed PCM thermal characteristics. A study was conducted to assess the performance benefits provided by the latent heat of the concrete wall combined with PCM. This study focuses on developing and testing heat barrier performance by incorporating PCM into wall external finishing, i.e. cement plaster and gloss paint. The effect of PCM inclusion in building wall were investigated by experimental work. The results indicate that incorporating PCM into the building wall reduced the surface temperature by up to 9 °C. Furthermore, the application of the PCM in the plaster layer is more reliable in reducing the internal wall surface temperature by a value of 8.1 °C when compared to the PCM in a painted coating. Painted wall panels experienced more significant temperature reduction differences than other wall panels, i.e. 9.2 °C and 9.5 °C, respectively. However, painted wall panels experienced higher internal surface temperatures than external surface temperatures compared to plastered wall panel at night. This could be due to the paint reactions, which are ineffective at releasing internal heat from the building at night. The yearly energy demand is decreased by 64.3% by incorporating PCM to the building wall, with a total annual electricity bill savings of 42.3% (8695.8 kWh yr−1). Therefore, it was concluded that wrapped PCM integrated into plaster layers on external surface building walls could decrease the indoor building temperature and thus contribute to conserving the energy required for an air conditioning system.
Avoidant Coping Is Associated with Quality of Life in Persons with Multiple Sclerosis with High Cognitive Reserve
Authors: Vervoordt Samantha M , Bradson Megan L , Arnett Peter A 
Published: July 2022

Abstract

Objective
The goal of this study was to determine the impact of the relationship between cognitive reserve and coping strategy on quality of life (QoL) outcomes in persons with MS (PwMS) across multiple domains.

Methods
We examined the effect of the interactions between coping style and cognitive reserve on QoL and disease burden in 97 persons with MS (PwMS). Coping strategy, either active or avoidant, was measured using the COPE inventory. We defined cognitive reserve as a composite measure of years of education and scores on the Shipley-2 Vocabulary subtest. QoL and disease burden were assessed using the Functional Assessment of MS (FAMS) scale and the Expanded Disability Status Scale, respectively. We examined both the FAMS individual subscales and the overall QoL score.

Results
For those with higher cognitive reserve, greater avoidant coping was associated with lower QoL for the thinking and fatigue subscale (p &lt; 0.001) and poorer overall QoL (p = 0.03); greater active coping was associated with poorer QoL for mobility (p = 0.001). However, these associations did not hold for those with lower cognitive reserve. Furthermore, there were no associations between coping strategy and cognitive reserve with disease burden.

Conclusions
This study extends previous findings by demonstrating that avoidant coping, rather than active coping, is associated with poorer thinking and fatigue and overall QoL only for PwMS with greater cognitive reserve. Counseling PwMS on the impact of coping strategies on QoL outcomes, especially for those with greater cognitive reserve, may improve quality of life outcomes in this population.
Familial and syndromic forms of arachnoid cyst implicate genetic factors in disease pathogenesis
Authors: Qureshi Hanya M , Mekbib Kedous Y , Allington Garrett , Elsamadicy Aladine A , Duy Phan Q , Kundishora Adam J , Jin Sheng Chih , Kahle Kristopher T 
Published: July 2022

AbstractArachnoid cysts (ACs) are the most common space-occupying lesions in the human brain and present significant challenges for clinical management. While most cases of ACs are sporadic, nearly 40 familial forms have been reported. Moreover, ACs are seen with increased frequency in multiple Mendelian syndromes, including Chudley–McCullough syndrome, acrocallosal syndrome, and autosomal recessive primary ciliary dyskinesia. These findings suggest that genetic factors contribute to AC pathogenesis. However, traditional linkage and segregation approaches have been limited in their ability to identify causative genes for ACs because the disease is genetically heterogeneous and often presents asymptomatically and sporadically. Here, we comprehensively review theories of AC pathogenesis, the genetic evidence for AC formation, and discuss a different approach to AC genomics that could help elucidate this perplexing lesion and shed light on the associated neurodevelopmental phenotypes seen in a significant subset of these patients.
Mexiletine for recurrent ventricular tachycardia in adult patients with structural heart disease and implantable cardioverter defibrillator: an EHRA systematic review
Authors: Farkowski Michal Miroslaw , Karlinski Michal , Pytkowski Mariusz , de Asmundis Carlo , Lewandowski Michal , Mugnai Giacomo , Conte Giulio , Marijon Eloi , Anic Ante , Boveda Serge , Providencia Rui 
Published: July 2022

Abstract
The aim of the study was to systematically review evidence on the effectiveness and safety of oral mexiletine administered in monotherapy or in combination with other antiarrhythmic drugs for recurrent ventricular arrhythmia (ventricular tachycardia/ventricular fibrillation, VT/VF) in adult patients with structural heart disease (SHD) and implantable cardioverter defibrillators (ICDs). We systematically searched MEDLINE, Embase, and CENTRAL databases from inception to 27 August 2021 for prospective and retrospective studies investigating mexiletine in the target population. The main outcome was the reduction of ICD therapy. The main safety outcome was the presence of any serious adverse events (SAEs) leading to mexiletine discontinuation. Study quality was assessed using the Cochrane risk of bias tool or the Newcastle–Ottawa scale. Four studies comprising 86 mexiletine recipients were included in the review. We also obtained individual data of 50 patients from two studies. Ischaemic cardiomyopathy (ICM) was present in 86% of patients. The quality of included studies was moderate/low. A narrative review was undertaken as studies varied widely in terms of study population and treatment. Across studies, mexiletine treatment (with or without amiodarone) seemed to consistently reduce the number of ICD therapies especially in a population where catheter ablation (CA) was unsuccessful or contraindicated. In ICM patients deemed eligible for CA, mexiletine seemed to be inferior to CA. Mexiletine was discontinued in 14% of cases, mainly for gastrointestinal or neurological SAE. Mexiletine seems to be an option for the long-term treatment of recurrent VT/VF in adult patients with SHD, especially ICM, and ICD in whom CA was unsuccessful or not suitable.
Ckmt1 is Dispensable for Mitochondrial Bioenergetics Within White/Beige Adipose Tissue
Authors: Politis-Barber Valerie , Petrick Heather L , Raajendiran Arthe , DesOrmeaux Genevieve J , Brunetta Henver S , dos Reis Larissa M , Mori Marcelo A , Wright David C , Watt Matthew J , Holloway Graham P 
Published: July 2022

Abstract
Within brown adipose tissue (BAT), the brain isoform of creatine kinase (CKB) has been proposed to regulate the regeneration of ADP and phosphocreatine in a futile creatine cycle (FCC) that stimulates energy expenditure. However, the presence of FCC, and the specific creatine kinase isoforms regulating this theoretical model within white adipose tissue (WAT), remains to be fully elucidated. In the present study, creatine did not stimulate respiration in cultured adipocytes, isolated mitochondria or mouse permeabilized WAT. Additionally, while creatine kinase ubiquitous-type, mitochondrial (CKMT1) mRNA and protein were detected in human WAT, shRNA-mediated reductions in Ckmt1 did not decrease submaximal respiration in cultured adipocytes, and ablation of CKMT1 in mice did not alter energy expenditure, mitochondrial responses to pharmacological β3-adrenergic activation (CL 316, 243) or exacerbate the detrimental metabolic effects of consuming a high-fat diet. Taken together, these findings solidify CKMT1 as dispensable in the regulation of energy expenditure, and unlike in BAT, they do not support the presence of FCC within WAT.
Migration patterns of Greenland halibut in the North Atlantic revealed by a compiled mark–recapture dataset
Authors: Vihtakari Mikko , Elvarsson Bjarki Þór , Treble Margaret , Nogueira Adriana , Hedges Kevin , Hussey Nigel E , Wheeland Laura , Roy Denis , Ofstad Lise Helen , Hallfredsson Elvar H , Barkley Amanda , Estévez-Barcia Daniel , Nygaard Rasmus , Healey Brian , Steingrund Petur , Johansen Torild , Albert Ole Thomas , Boje Jesper 
Published: July 2022

AbstractMarine fisheries are often allocated to stocks that reflect pragmatic considerations and may not represent the species’ spatial population structure, increasing the risk of mismanagement and unsustainable harvesting. Here we compile mark–recapture data collected across the North Atlantic to gain insight into the spatial population structure of Greenland halibut (Reinhardtius hippoglossoides), an issue that has been unresolved for decades. The dataset contains 168130 fish tagged from 1952 to 2021, with 5466 (3.3%) recaptured individuals. Our results indicate that fish tagged at &lt;50 cm body length migrate at higher rates, suggesting that mark–recapture studies on adult individuals underestimate population-level migration rates. We find evidence for migrations across management units in the North Atlantic indicating two regional offshore populations: one in the Northeast Atlantic, where the West Nordic and Northeast Arctic stocks, currently managed separately, likely belong to a single population that spans from the Kara Sea to Southeast Greenland; and one in the Northwest Atlantic where migration was observed between the Newfoundland and Labrador stock and the Northwest Arctic stock in Davis Strait and Baffin Bay. Our findings indicate complex population structure with implications for international and domestic fisheries management of this long-lived species.
Do People Want Democracy Aid? Survey Experimental Evidence from Africa
Authors: Doces John A , Meyer Mark J 
Published: July 2022

Abstract
In Africa, international donors have increasingly promoted democracy and election monitoring. Do Africans want them to do this or would they prefer some other purpose? We argue respondents will least prefer democracy compared to other purposes because (i) there are other possible uses, like healthcare, that are more in need; (ii) aid has a political salience of control that other purposes do not have; and (iii) democracy and monitoring in Africa often yield negative externalities, while other purposes produce positive externalities. To test this claim, we conducted two rounds of survey experiments in Côte d’Ivoire and Uganda, and then again in Côte d’Ivoire with an extension to Senegal. Our surveys employ a conjoint analysis in which respondents compare two possible development projects. Each survey includes several dimensions, including the project’s purpose, which is where we locate democracy and monitoring and alternative purposes such as healthcare or education. Results indicate that democracy and monitoring are the least preferred purposes compared to other purposes. This does not mean that they do not want democracy, nor that they do not want donors to promote democracy, but rather that compared to other possible purposes, democracy is the least preferred use of aid funds.