bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring Theater Neuroscience: Using Wearable Functional Near-infrared Spectroscopy to Measure the Sense of Self and Interpersonal Coordination in Professional Actors
Authors: Greaves Dwaynica A. , Pinti Paola , Din Sara , Hickson Robert , Diao Mingyi , Lange Charlotte , Khurana Priyasha , Hunter Kelly , Tachtsidis Ilias , Hamilton Antonia F. de C. 
Published: September 2022

Abstract
Ecologically valid research and wearable brain imaging are increasingly important in cognitive neuroscience as they enable researchers to measure neural mechanisms of complex social behaviors in real-world environments. This article presents a proof of principle study that aims to push the limits of what wearable brain imaging can capture and find new ways to explore the neuroscience of acting. Specifically, we focus on how to build an interdisciplinary paradigm to investigate the effects of taking on a role on an actor's sense of self and present methods to quantify interpersonal coordination at different levels (brain, physiology, behavior) as pairs of actors rehearse an extract of a play prepared for live performance. Participants were six actors from Flute Theatre, rehearsing an extract from Shakespeare's A Midsummer Night's Dream. Sense of self was measured in terms of the response of the pFC to hearing one's own name (compared with another person's name). Interpersonal coordination was measured using wavelet coherence analysis of brain signals, heartbeats, breathing, and behavior. Findings show that it is possible to capture an actor's pFC response to their own name and that this response is suppressed when an actor rehearses a segment of the play. In addition, we found that it is possible to measure interpersonal synchrony across three modalities simultaneously. These methods open the way to new studies that can use wearable neuroimaging and hyperscanning to understand the neuroscience of social interaction and the complex social–emotional processes involved in theatrical training and performing theater.
The Making of Religion
Authors: Ferreira Dias João 
Published: September 2022

Abstract
This essay aims to focus on the concept of religion and its conceptual implications in the observation of African religions, taking the Yorùbá and Candomblé religious attitudes and beliefs as case studies. I intend to trace a new itinerary in the conceptualization of African religious experiences, using native structures as the setting for theory. I point out that African-Yorùbá religious experience is deeply merged with ritual practice – religion is made – and tied to a sense of origins and duties that must be fulfilled. In that vein, I present alternative categories to the classic ones of monotheism, polytheism, and pantheon.
Reevaluating the Role of Inter-Polity Boundaries (tꜢšw) in Middle and New Kingdom Egypt
Authors: Siegel Oren 
Published: September 2022

Abstract
Chains of frontier fortresses and the presence of boundary stelae have understandably encouraged scholars to emphasize parallels between Pharaonic political boundaries and contemporary political borders. However, ancient Egyptian territoriality and conceptions of political boundaries differed in several key ways. First, Pharaonic boundaries were not defined by their permeability, but rather their capacity to be altered by royal action. Second, specific territorial claims were often less vital than the sovereign act of claiming or marking a boundary. Finally, ancient Egyptian boundaries were often discussed in personal terms, as belonging to a particular pharaoh. They were not abstracted, linear features that aspired to an ahistorical permanence, but functioned as powerful, performative displays of political authority in liminal spaces. Recognizing these fundamental differences builds upon the insights of earlier scholarship and provides new perspectives on Pharaonic boundary-making practices.
The Role of Confirmation in Christian Initiation
Authors: Alfsvåg Knut 
Published: September 2022

Abstract
The relation between baptism, chrismation, and first communion has developed differently in different denominations. An important characteristic of this development is the establishment of confirmation as a separate rite during medieval times. Despite Luther’s being skeptical toward confirmation, which he considered a human invention with Semipelagian connotations, it was adopted for catechetical purposes by Martin Bucer, partly as a compromising gesture toward the Anabaptists. Today, confirmation is a well-established rite of passage with a theologically complicated history administered within a context where a new awareness of the rites of initiation in the early church has opened old debates concerning chrismation, confirmation, and the communion of infants. The article investigates how a knowledge of this history can help us develop an ecumenically relevant theology of confirmation and catechesis carried by a strong understanding of baptism as the undisputed rite of Christian initiation.
The Pronunciation of the Dagesh Lene in the Tiberian Hebrew Tradition
Authors: Wormser Yehonatan 
Published: September 2022

Abstract
It is commonly assumed that the distinction between the dagesh forte (marking a geminated consonant) and the dagesh lene (marking a plosive, non-geminated pronunciation of the letters ‮בגדכפ“ת‬‎) can be traced to the original Tiberian reading tradition. The use of only one sign for both entities in the Tiberian vocalization, however, as well as several findings from Tiberian-related sources, lead to the conclusion that both types of degeshim were realized with gemination in the Tiberian tradition. In contrast, there are texts with Babylonian and Palestinian vocalization that differentiate between the two types, probably representing a distinction in their realization. These facts suggest that this distinction, an integral component of standard Hebrew grammar, maintained in many oral traditions, is not based on the Tiberian tradition and appears now in non-Tiberian traditions only.
Ancient Versions and Enigmatic Valleys
Authors: Polak Frank H. 
Published: September 2022

Abstract
This paper concerns the rendering of Hebrew “terebinth” as “valley,” and the mention of a “valley” near Hebron in a plus. In the Targums, the Vulgate and Aquila the “terebinths” of Moreh and Mamre (Gen 12:6; 18:1; Deut 11:30) are represented by a term meaning “valley.” According to the standard analysis this rendering avoids the association of these precincts with non-monotheistic cults. However, this theory fails to explain the use of the term “valley.” Midrashic comments point to anti-Samaritan polemics, based on Deut 11:30, where “terebinth” and “plain,” Arabah, meet. Furthermore, a plus of the Septuagint and the Samaritan mentions “the valley of Hebron” (Gen 23:2; cf. the gloss, 37:14). These constellations are related to a particular sensitivity for the status of the Mamre region in the Persian era and beyond as it belongs to Idumaea, and its religious practice includes non-monotheistic cults.
Customs Union, Wage Inequality and Welfare in General Equilibrium
Authors: Marjit Sugata , Sen Sharmi , Gupta Kausik 
Published: September 2022

The article attempts to consider the impact of a customs union formed between two small countries embedded in the global economy and trading in intermediates, in terms of a general equilibrium framework. It shows that with such a union both countries will gain, although there will be asymmetric effect on wage inequality. However, with higher capital stock the significance of the formation of customs union will be undermined. It also shows that perfect international capital mobility will lead to finite changes in the economy, shutting down the less capital intensive unskilled export sector in each country, which in turn makes the bilateral union irrelevant. Further tariff reduction will increase inequality in both countries. We have also considered the welfare effects of formation of customs union in the form of tariff cut and such a tariff reduction unequivocally improves welfare of the customs union irrespective of small country and large country assumptions, without any intra-union income transfer. JEL Codes: F02, F11, F55, F68
Strategic Entry with Correlated Private Information
Authors: Wang Rongyu 
Published: September 2022

This article studies how the correlation of players’ private information affects their strategic be haviour. We introduce information correlation into a static two-player strategic substitutes entry game. The degree of information correlation is measured by the correlation coefficient of a symmetric joint normal distribution, which is used to model players’ prior distribution. It is found that a cutoff strategy cannot be used for all values of correlation coefficient to solve the game, and there exists a threshold correlation coefficient value to differentiate the unique-equilibrium and the multiple (three)-equilibria situations, given other parameters. Finally, by comparative statics analysis of symmetric equilibrium strategies, we find that increasing the payoff of entry encourages players to adopt a lower entry threshold, while increasing the information correlation or jointly increasing the variances of prior distribution increases the positive entry threshold and lowers the negative entry threshold. JEL Codes: C72, D21, D82, L13
Paracentesis for cancer-related ascites in palliative care: An international, prospective cohort study
Authors: Seah Davinia SE , Wilcock Andrew , Chang Sungwon , Sousa Mariana S , Sinnarajah Aynharan , Teoh Cy Oun , Allan Simon , Chye Richard , Doogue Matthew , Hunt Jane , Agar Meera , Currow David C 
Published: September 2022

Background: Paracentesis is commonly undertaken in patients with cancer-related ascites. Aim: To systematically investigate the symptomatic benefits and harms experienced by patients with cancer undergoing paracentesis using real-world data in the palliative care setting. Design: Prospective, multisite, observational, consecutive cohort study. Benefits and harms of paracentesis were assessed between 01/07/2018 and 31/02/2021 as part of routine clinical assessments by treating clinicians at four timepoints: (T0) before paracentesis; (T1) once drainage ceased; (T2) 24 h after T1 and (T3) 28 days after T1 or next paracentesis, if sooner. Setting/participants: Data were collected from 11 participating sites across five countries (Australia, England, Hong Kong, Malaysia and New Zealand) on 111 patients undergoing paracentesis via a temporary (73%) or indwelling (21%) catheter: 51% male, median age 69 years, Australia-modified Karnofsky Performance Score 50. Results: At T1 ( n = 100), symptoms had improved for most patients (81%), specifically abdominal distension (61%), abdominal pain (49%) and nausea (27%), with two-thirds experiencing improvement in ⩾2 symptoms. In the remaining patients, symptoms were unchanged (7%) or worse (12%). At least one harm occurred in 32% of patients, the most common being an ascitic leak ( n = 14). By T3, 89% of patients had experienced some benefit and 36% some harm, including four patients who experienced serious harm, one of which was a fatal bowel perforation. Conclusion: Most patients obtained rapid benefits from paracentesis. Harms were less frequent and generally mild, but occasionally serious and fatal. Our findings help inform clinician-patient discussions about the potential outcomes of paracentesis in this frail population.
Verbascoside represses malignant phenotypes of esophageal squamous cell carcinoma cells by inhibiting CDC42 via the HMGB1/RAGE axis
Authors: Ji Mingming , Sun Jian , Zhao Jun 
Published: September 2022

Background As an aggressive human malignancy, esophageal squamous cell carcinoma (ESCC) is prevalent globally, especially in China. Verbascoside (VE) exerts anti-cancer effects in several human cancers. This work was to investigate the effects of VE on ESCC cells. Methods Esophageal squamous cell carcinoma cell proliferation, apoptosis, migration, and invasion were assessed by CCK-8, TUNEL, and Transwell assays. Gene and protein levels were detected by RT-qPCR and western blotting. CDC42 activity was evaluated by G-lisa assay. Results Verbascoside significantly inhibited cell proliferation, migration, and invasion and induced cell apoptosis in ESCC cells. Furthermore, it was found that VE markedly inhibited HMGB1 and RAGE expression in a dose-dependent manner. Besides, HMGB1/RAGE upregulation partially reversed the anti-cancer effects of VE on ESCC cells. VE repressed HMGB1/RAGE-induced CDC42 activation in ESCC cells. In addition, ML141-mediated CDC42 inactivation further enhanced the effect of VE on ESCC cell proliferation, apoptosis, migration, and invasion. Conclusions Our findings indicated that VE has significant anti-tumor potential in ESCC by suppressing HMGB1/RAGE-dependent CDC42 activation.
Risk of livedo with antiphospholipid antibodies in patients with systemic lupus erythematosus: A systematic review and meta-analysis
Authors: Loiseau Pierre , Foret Thomas , DeFilippis Ersilia M , Risse Jessie , Etienne Anais D , Dufrost Virginie , Moulinet Thomas , Erkan Doruk , Devilliers Hervé , Wahl Denis , Zuily Stéphane 
Published: September 2022

Background Livedo is a well-known skin condition in patients with systemic lupus erythematosus (SLE) which correspond to small vessels involvement. The influence of antiphospholipid antibodies (aPL) on the occurrence of livedo is controversial. The aim of our study was to estimate the risk of livedo associated with aPL in patients with SLE. Methods We conducted a systematic review and meta-analysis of the literature from 1977 to 2021 to estimate the risk of livedo in SLE patients according to different aPL profiles. Data sources were PubMed, Embase, Cochrane Library, hand search, and reference lists of studies. Studies were selected if they included SLE patients with descriptions of the exposure to aPL and the outcome ( livedo). Two independent investigators assessed study eligibility, quality, and extracted patient characteristics from each study as well as exposure (aPL) and outcome ( livedo). Risk estimates were pooled using random effects models and sensitivity analyses. For all stages of the meta-analysis, we followed the PRISMA guidelines. PROSPERO registration number: CRD42015027377. Results Of the 2,355 articles identified, 27 were included with a total of 4,810 SLE patients. The frequency of livedo was 25.5% in aPL-positive patients and 13.3% in aPL-negative patients. The overall Odds Ratio (OR) for livedo in aPL-positive patients compared to aPL-negative patients was 2.91 (95% CI; 2.17–3.90). The risk of livedo was significantly increased for most of aPL subtypes, including lupus anticoagulant (LA) (OR = 4.45 [95% CI; 2.21–8.94]), IgG anticardiolipin (OR = 3.95 [95% CI; 2.34–6.65]), and IgG anti-β2-glycoprotein 1 (OR = 3.49 [95% CI; 1.68–7.27]). Conclusions We demonstrated in this meta-analysis an excess risk of livedo in aPL-positive SLE patients compared to aPL-negative patients. For daily practice, in patients with SLE, livedo associated with aPL could correspond to a peculiar group of patients with small vessel disease. Livedo could be a good candidate for inclusion in future classification criteria for antiphospholipid syndrome.
Oral oncolytic monitoring pilot with patient-reported outcomes and adherence assessments
Authors: Signorelli Jessie , Bell Christopher , Monaco Stephanie 
Published: September 2022

Introduction Patients on oral oncolytics are responsible for self-monitoring adherence and adverse drug reactions (ADRs). Oncology pharmacists are in position to focus on quality and safety of care for patients on oncolytics while providing communication between the patient, physician, and specialty pharmacies. This pilot aimed to monitor patients treated by our leukemia team initiated on oral oncolytics. Methods From July 2020 to February 2021, patients treated by our leukemia team newly started on oncolytics were included. Pharmacists performed medication reconciliation and drug interaction screening on initiation of oral oncolytic. Pharmacists followed up at predefined intervals. On follow up adherence was assessed using the Morisky Medication Adherence Scale-8 (MMAS-8) and patient reported outcomes (PROs) were assessed using the revised Edmonton Symptom Assessment Scale (ESAS-r). After each follow-up, a note was placed in the chart with assessment scores and recommendations. Results A total of 32 patients were screened with 19 patients included. Oral oncolytics included: imatinib (4), dasatinib (5), ponatinib (1), gilteritinib (2), enasidenib (1), and venetoclax (6). Fourteen drug interactions were identified, 11 medications discontinued, nine medications added, and two medications doses were changed. Twenty-six adherence assessments were performed with 21, 4, and 1 assessment demonstrating adherence, medium adherence, and low adherence, respectively. 62 ESAS-r assessments were performed with 64% reported as no symptoms, 17% as mild, 13% as moderate, and 5% as severe symptoms. Twenty laboratory tests were ordered from pharmacist recommendation on initiation and follow-up. Conclusion This pilot demonstrated the role pharmacists play in oral oncolytic monitoring and symptom management.
Opportunities for transitional care and care continuity following hospital discharge of older people in three Nordic cities: A comparative study
Authors: Liljas Ann E.M. , Pulkki Jutta , Jensen Natasja K. , Jämsen Esa , Burström Bo , Andersen Ingelise , Keskimäki Ilmo , Agerholm Janne 
Published: September 2022

Aim: To outline and discuss care transitions and care continuity following hospital discharge of older people with complex care needs in three Nordic cities: Copenhagen, Tampere and Stockholm. Methods: Data on potential pathways following hospital discharge of older people were obtained from existing literature and expert consultations. The pathways for each system were outlined and presented in three figures. The hospital discharge process of the systems was then compared. Results: In all three care systems, the main care path from hospital is to home. Short-term intermediate healthcare can be provided in all three systems, possibly creating additional care transitions; however, once home, extensive home healthcare may prevent further care transitions. Opportunities for continuity of care include needs assessments (all cities) and meetings with the patient about care upon return home (Copenhagen, Stockholm). Yet this is challenged by lack of transfer of information (Tampere) and patients’ having to apply for some services themselves (Tampere, Stockholm). Conclusions: Comparisons of the discharge processes studied suggest that despite individual care planning and short- and long-term care options, transitional care and care continuity are challenged by limited access as some services need to be applied for by the older person themselves.
Incompressible ankle arteries predict increased morbidity and mortality in patients with an elevated ankle brachial index
Authors: Laivuori Mirjami , Peltonen Essi , Venermo Maarit , Hakovirta Harri 
Published: September 2022

Objectives Patients with an elevated ankle brachial index (ABI) > 1.3 have a high burden of disease and poorer outcome compared to patients with a lower ABI. Previously differences between patients with ABI > 1.3 have not been studied in detail. The aim of this study was to analyze the morbidity and mortality of patients with ABI > 1.3. Methods ABI measurements were performed in the vascular laboratory of Turku university hospital 2011–2013. Patients with ABI>1.3 in at least one lower limb were included in the study and divided into 3 groups: At least one lower limb ABI 1.3–2.5 but both limbs <2.5 (group 1), one limb ABI ≥2.5 (group 2), both limbs ABI ≥ 2.5 (group 3). Results 534 patients were included in the study. The patients in groups 2 and 3 were more often female ( p < .001), older ( p < .001), had more diabetes ( p = .013), coronary artery disease ( p = .001) and chronic heart ( p = .010) and kidney failure ( p = .013) compared to patients in group 1. The survival of patients in group 2 and 3 was significantly poorer compared to the patients in group 1 (HR1.6, 95% CI 1.2–2.2, p = .002 and 1.7, 95% CI 1.2–2.3, p < .001, respectively). Overall and cardiovascular mortality was higher in groups 2 and 3 than group 1.39.5% of patients with incompressible ankle arteries (ABI ≥ 2.5) in both lower limbs had toe pressure (TP) <50 mmHg and a poorer survival compared to patients with a higher TP. Conclusions Patients with incompressible ankle arteries have significantly higher overall and cardiovascular mortality and a greater burden of disease compared to the patients with a measurable yet abnormally high ABI. TP is a useful diagnostic tool when ABI is immeasurably high. All patients with ABI > 1.3 should be considered as high cardiovascular risk patients.
Effect of early integrated robot-assisted gait training on motor and balance in patients with acute ischemic stroke: a single-blinded randomized controlled trial
Authors: Meng Guilin , Ma Xiaoye , Chen Pengfei , Xu Shaofang , Li Mingliang , Zhao Yichen , Jin Aiping , Liu Xueyuan 
Published: September 2022

Background: Gait disruption is a common poststroke problem. Robot-assisted gait training (RAGT) might improve motor function, balance, and activities of daily living. Objective: We compared the clinical effectiveness of early integrated RAGT using the Walkbot robotic gym with an intensity-matched enhanced lower limb therapy (ELLT) program and with conventional rehabilitation therapy (CRT) in patients with acute ischemic stroke. Methods: A total of 192 patients with acute ischemic stroke were randomly assigned (1:1:1) to receive RAGT, ELLT, or CRT. All three groups received 45 min of training daily, 3 days a week, for 4 weeks consecutively. Before and after the 4-week treatment, the patients were assessed based on a 6-minute walking test (6MWT), functional ambulation classification (FAC), timed up and go (TUG) test, dual-task walking (DTW) test, Tinetti’s test, Barthel’s index (BI), stroke-specific quality of life (SS-QOL) scale, and gait analysis parameters. Results: After the 4-week intervention, the results of the 6MWT, FAC, TUG, DTW, Tinetti’s test, BI, SS-QOL, and gait in the three groups significantly improved. Compared with ELLT and CRT groups, participants in the RAGT group had a better performance in 6MWT (199.11 ± 60.72 versus 182.47 ± 59.72 versus 173.69 ± 40.58, p = 0.035), FAC (4.10 ± 0.91 versus 3.69 ± 0.88 versus 3.58 ± 0.81, p = 0.044), DTW (10.29 ± 2.38 versus 12.92 ± 2.64 versus 13.89 ± 2.62, p = 0.031), SS-QOL (184.46 ± 20.53 versus 165.39 ± 20.49 versus 150.72 ± 20.59, p = 0.012), velocity (0.66 ± 0.22 versus 0.55 ± 0.23 versus 0.51 ± 0.20, p = 0.008), cycle duration (1.38 ± 0.40 versus 1.50 ± 0.38 versus 1.61 ± 0.30, p = 0.040), and swing phase symmetry ratio (SPSR, 1.10 ± 0.33 versus 1.21 ± 0.22 versus 1.48 ± 0.25, p = 0.021). The TUG, Tinetti’s test, BI, and RMT results were similar, however. Conclusion: In the acute stroke phase, early integrated RAGT showed greater performance in gait rehabilitation than CRT and ELLT. Registration: ChiCTR1900026225