bluuebunny/crossref_metadata_2025_split huggingface dataset:
The digital transformation of industry and the world of work
Authors:   ILO
Published: January 2022

AbstractThis chapter traces the rise of the digital economy and digital platforms, focusing on digital labour platforms in particular. It assesses the impact of such platforms on different economic sectors and labour markets, highlighting the distinctive aspects of digital labour platforms that are transforming the world of work. It gives some estimates of the number of platform companies and the number of workers whose work is mediated through these platforms based on the available literature. It also discusses the roles of data and finance in the rapid rise of these platforms, and the challenges the platforms pose to both businesses and workers.
Electroweak phase transition triggered by fermion sector
Authors: Cao Qing-Hong , Hashino Katsuya , Li Xu-Xiang , Ren Zhe , Yu Jiang-Hao 
Published: January 2022

Abstract
To realize first-order electroweak phase transition, it is necessary to generate a barrier in the thermal Higgs potential, which is usually triggered by scalar degree of freedom. We instead investigate phase transition patterns in pure fermion extensions of the standard model, and find that additional fermions with mass hierarchy and mixing could develop such a barrier and realize a strongly first-order phase transition in such models. In the Higgs potential with polynomial parametrization, the barrier can be generated in the following two patterns by fermionic reduction effects: (I) positive quadratic term, negative cubic term and positive quartic term or (II) positive quadratic term, negative quartic term and positive higher dimensional term, such as dimensional 6 operator.
Dark confinement and chiral phase transitions: gravitational waves vs matter representations
Authors: Reichert Manuel , Sannino Francesco , Wang Zhi-Wei , Zhang Chen 
Published: January 2022

Abstract
We study the gravitational-wave signal stemming from strongly coupled models featuring both, dark chiral and confinement phase transitions. We therefore identify strongly coupled theories that can feature a first-order phase transition. Employing the Polyakov-Nambu-Jona-Lasinio model, we focus our attention on SU(3) Yang-Mills theories featuring fermions in fundamental, adjoint, and two-index symmetric representations. We discover that for the gravitational-wave signals analysis, there are significant differences between the various representations. Interestingly we also observe that the two-index symmetric representation leads to the strongest first-order phase transition and therefore to a higher chance of being detected by the Big Bang Observer experiment. Our study of the confinement and chiral phase transitions is further applicable to extensions of the Standard Model featuring composite dynamics.
Galois orbits of TQFTs: symmetries and unitarity
Authors: Buican Matthew , Radhakrishnan Rajath 
Published: January 2022

Abstract
We study Galois actions on 2+1D topological quantum field theories (TQFTs), characterizing their interplay with theory factorization, gauging, the structure of gapped boundaries and dualities, 0-form symmetries, 1-form symmetries, and 2-groups. In order to gain a better physical understanding of Galois actions, we prove sufficient conditions for the preservation of unitarity. We then map out the Galois orbits of various classes of unitary TQFTs. The simplest such orbits are trivial (e.g., as in various theories of physical interest like the Toric Code, Double Semion, and 3-Fermion Model), and we refer to such theories as unitary “Galois fixed point TQFTs”. Starting from these fixed point theories, we study conditions for preservation of Galois invariance under gauging 0-form and 1-form symmetries (as well as under more general anyon condensation). Assuming a conjecture in the literature, we prove that all unitary Galois fixed point TQFTs can be engineered by gauging 0-form symmetries of theories built from Deligne products of certain abelian TQFTs.
Gluino-SUGRA scenarios in light of FNAL muon g – 2 anomaly
Authors: Li Zhuang , Liu Guo-Li , Wang Fei , Yang Jin Min , Zhang Yang 
Published: January 2022

Abstract
Gluino-SUGRA ($$ \overset{\sim }{g} $$

g
~

SUGRA), which is an economical extension of the predictive mSUGRA, adopts much heavier gluino mass parameter than other gauginos mass parameters and universal scalar mass parameter at the unification scale. It can elegantly reconcile the experimental results on the Higgs boson mass, the muon g − 2, the null results in search for supersymmetry at the LHC and the results from B-physics. In this work, we propose several new ways to generate large gaugino hierarchy (i.e. M3 » M1, M2) for $$ \overset{\sim }{g} $$

g
~

SUGRA model building and then discuss in detail the implications of the new muon g − 2 results with the updated LHC constraints on such $$ \overset{\sim }{g} $$

g
~

SUGRA scenarios. We obtain the following observations: (i) for the most interesting M1 = M2 case at the GUT scale with a viable bino-like dark matter, the $$ \overset{\sim }{g} $$

g
~

SUGRA can explain the muon g − 2 anomaly at 1σ level and be consistent with the updated LHC constraints for 6 ≤ M3/M1 ≤ 9 at the GUT scale; (ii) For M1 : M2 = 5 : 1 at the GUT scale with wino-like dark matter, the $$ \overset{\sim }{g} $$

g
~

SUGRA model can explain the muon g − 2 anomaly at 2σ level and be consistent with the updated LHC constraints for 3 ≤ M3/M1 ≤ 3.2 at the GUT scale; (iii) For M1 : M2 = 3 : 2 at the GUT scale with mixed bino-wino dark matter, the $$ \overset{\sim }{g} $$

g
~

SUGRA model can explain the muon g − 2 anomaly at 1σ level and be consistent with the updated LHC constraints for 6.9 ≤ M3/M1 ≤ 7.5 at the GUT scale. Although the choice of heavy gluino will always increase the FT involved, some of the 1σ/2σ survived points of $$ \Delta {a}_{\mu}^{\mathrm{combine}} $$
∆

a
μ
combine

can still allow low EWFT of order several hundreds and be fairly natural. Constraints from (dimension-five operator induced) proton decay are also discussed.
On BGG resolutions of unitary modules for quiver Hecke and Cherednik algebras
Authors: Bowman C. , Norton E. , Simental J. 
Published: January 2022

AbstractWe provide a homological construction of unitary simple modules of Cherednik and Hecke algebras of type A via BGG resolutions, solving a conjecture of Berkesch–Griffeth–Sam. We vastly generalize the conjecture and its solution to cyclotomic Cherednik and Hecke algebras over arbitrary ground fields, and calculate the Betti numbers and Castelnuovo–Mumford regularity of certain symmetric linear subspace arrangements.
First-line high-dose therapy and autologous blood stem cell transplantation in patients with primary central nervous system non-Hodgkin lymphomas—a single-centre experience in 61 patients
Authors: Brezina T. , von Dewitz H. , Schroeder T. , Ullrich S. , Nachtkamp K. , Reifenberger G. , Malzkorn B. , Sabel M. , Haas R. , Kobbe G. 
Published: January 2022

AbstractPrimary central nervous system non-Hodgkin lymphomas (PCNS-NHLs) are extranodal B-cell lymphomas with poor prognosis. The role of high-dose therapy (HDT) followed by autologous blood stem cell transplantation (ASCT) as first-line therapy is still not clear. We retrospectively collected long-term follow up data of 61 consecutive patients with PCNS-NHL at the University Hospital Düsseldorf from January 2004 to December 2016. Thirty-six patients were treated with conventional chemoimmunotherapy (cCIT) only (CT-group). Seventeen patients received an induction cCIT followed by HDT and ASCT. In the CT-group, the overall response rate (ORR) was 61% (CR 47%, PR 14%), and there were 8% treatment-related deaths (TRD). Progression-free survival (PFS) was 31.8 months, and overall survival (OS) was 57.3 months. In the HDT-group, the ORR was 88% (59% CR, 29% PR), and there were 6% TRD. Median PFS and OS were not reached at 5 years. The 5-year PFS and OS were 64.7%. After a median follow up of 71 months, 10 patients (59%) were still alive in CR/PR following HDT and ASCT, one patient was treated for progressive disease (PD), and 7 had died (41%, 6 PD, 1 TRD). All patients achieving CR prior to HDT achieved durable CR. In the CT-group, 8 patients (22%) were alive in CR/PR after a median follow-up of 100 months. Twenty-eight patients died (78%, 24 PD, 2 TRD, 2 deaths in remission). In the univariate analysis, the HDT-group patients had significantly better PFS (not reached vs 31.8 months, p = 0.004) and OS (not reached vs 57.3 months, p = 0.021). The multivariate analysis showed HDT was not predictive for survival. Treatment with HDT + ASCT is feasible and offers the chance for long-term survival with low treatment-related mortality in younger patients. In this analysis, ORR, PFS and OS were better with HDT than with conventional cCIT alone. This result was not confirmed in the multivariate analysis, and further studies need to be done to examine the role of HDT in PCNSL.
Prediction of procedural success of transcatheter mitral valve repair with normal and extended clip arms
Authors: Kirschfink Annemarie , Alachkar Mhd Nawar , Almalla Mohammad , Grebe Julian , Vogt Felix , Schröder Jörg , Frick Michael , Marx Nikolaus , Altiok Ertunc 
Published: January 2022

AbstractTMVR using different clip sizes is a treatment option for selected patients with mitral regurgitation (MR). This study sought to identify predictors of successful transcatheter mitral valve repair (TMVR) by 3-dimensional (3D) echocardiography and to compare different effects of the larger XTR and the smaller NT/NTR devices. 3D transesophageal echocardiography was performed on 54 patients with secondary MR undergoing TMVR with one clip (55.6% NT/NTR, 44.4% XTR). All NT/NTR and 96% of XTR patients had MR reduction ≤ 2+. Despite more severe baseline MR (3D vena contracta area (VCA): 0.67 ± 0.34 cm2 vs. 0.43 ± 0.19 cm2, p = 0.004) and greater mitral valve area (MVA) (6.8 ± 2.1 cm2 vs. 5.1 ± 1.6 cm2, p = 0.001) in the XTR group, MR severity after TMVR was not different between XTR and NT/NTR patients (3D VCA: 0.19 ± 0.14 vs. 0.17 ± 0.10, p = 0.51). Baseline 3D VCA > 0.45 cm2 in NT/NTR (AUC = 0.802, 95% CI 0.602 to 1.000) and 3D VCA > 0.54 cm2 in XTR devices (AUC = 0.868, 95% CI 0.719 to 1.000) were associated with ineffective MR reduction defined as residual VCA ≤ 0.2 cm2. Baseline MVA ≤ 4.2 cm2 in NT/NTR (AUC = 0.920, 95% CI 0.809 to 1.000) and MVA ≤ 6.0 cm2 in XTR devices (AUC = 0.865, 95% CI 0.664 to 1.000) were associated with postprocedural transmitral pressure gradient (TMPG) ≥ 5 mmHg. TMVR using the XTR device resulted in an equally effective reduction of MR despite of a greater baseline MR. Distinct cut-off values of baseline 3D VCA and MVA for prediction of successful MR reduction and postprocedural increase of TMPG were identified for the different devices.
BRCA1 Norway: comparison of classification for BRCA1 germline variants detected in families with suspected hereditary breast and ovarian cancer between different laboratories
Authors: Hovland Henrikke N. , Al-Adhami Rafal , Ariansen Sarah Louise , Van Ghelue Marijke , Sjursen Wenche , Lima Sigrid , Bolstad Marte , Berger Amund H. , Høberg-Vetti Hildegunn , Knappskog Per , Haukanes Bjørn Ivar , Aukrust Ingvild , Ognedal Elisabet 
Published: January 2022

AbstractPathogenic germline variants in Breast cancer susceptibility gene 1 (BRCA1) predispose carriers to hereditary breast and ovarian cancer (HBOC). Through genetic testing of patients with suspected HBOC an increasing number of novel BRCA1 variants are discovered. This creates a growing need to determine the clinical significance of these variants through correct classification (class 1–5) according to established guidelines. Here we present a joint collection of all BRCA1 variants of class 2–5 detected in the four diagnostic genetic laboratories in Norway. The overall objective of the study was to generate an overview of all BRCA1 variants in Norway and unveil potential discrepancies in variant interpretation between the hospitals, serving as a quality control at the national level. For a subset of variants, we also assessed the change in classification over a ten-year period with increasing information available. In total, 463 unique BRCA1 variants were detected. Of the 126 variants found in more than one hospital, 70% were interpreted identically, while 30% were not. The differences in interpretation were mainly by one class (class 2/3 or 4/5), except for one larger discrepancy (class 3/5) which could affect the clinical management of patients. After a series of digital meetings between the participating laboratories to disclose the cause of disagreement for all conflicting variants, the discrepancy rate was reduced to 10%. This illustrates that variant interpretation needs to be updated regularly, and that data sharing and improved national inter-laboratory collaboration greatly improves the variant classification and hence increases the accuracy of cancer risk assessment.
Cross Second Virial Coefficient of the H2O–CO System from a New Ab Initio Pair Potential
Authors: Hellmann Robert 
Published: January 2022

AbstractThe cross second virial coefficient $$B_{12}$$

B
12

for the interaction between water (H2O) and carbon monoxide (CO) was obtained with low uncertainty at temperatures from 200 K to 2000 K employing a new intermolecular potential energy surface (PES) for the H2O–CO system. This PES was fitted to interaction energies determined for about 58 000 H2O–CO configurations using high-level quantum-chemical ab initio methods up to coupled cluster with single, double, and perturbative triple excitations [CCSD(T)]. The cross second virial coefficient $$B_{12}$$

B
12

was extracted from the PES using a semiclassical approach. An accurate correlation of the calculated $$B_{12}$$

B
12

values was used to determine the dilute gas cross isothermal Joule–Thomson coefficient, $$\phi _{12}=B_{12}-T(\mathrm {d}B_{12}/\mathrm {d}T)$$

ϕ
12

=

B
12

-
T

(
d

B
12

/
d
T
)

. The predicted values for both $$B_{12}$$

B
12

and $$\phi _{12}$$

ϕ
12

agree reasonably well with the few existing experimental data and older calculated values and should be the most accurate estimates of these quantities to date.
Sustainable behavior in motion: designing mobile eco-driving feedback information systems
Authors: Gimpel Henner , Heger Sebastian , Wöhl Moritz 
Published: January 2022

AbstractEmissions from road traffic contribute to climate change. One approach to reducing the carbon footprint is providing eco-driving feedback so that drivers adapt their driving style. Research about the impact of eco-feedback on energy consumption is the basis for designing a mobile eco-driving feedback information system that supports drivers in reducing fuel consumption. This work develops design knowledge from existing knowledge. Subsequently, we implement a prototypical instantiation based on the derived knowledge. Insights from a field study suggest that our design artifact allows most drivers to decrease fuel consumption by 4% on average. The paper’s theoretical contribution is a set of design principles and an architecture of the proposed mobile eco-driving feedback information system. One recommendation is to provide normative feedback that compares drivers with each other. This feedback appears to encourage drivers to decrease their fuel consumption additionally. The design knowledge may support researchers and practitioners in implementing efficient eco-driving feedback information systems.
Preparation of medical Mg–Zn alloys and the effect of different zinc contents on the alloy
Authors: Hu Yunpeng , Guo Xuan , Qiao Yang , Wang Xiangyu , Lin Qichao 
Published: January 2022

AbstractIn recent years, along with the development and application of magnesium alloys, magnesium alloys have been widely used in automotive, aerospace, medicine, sports, and other fields. In the field of medical materials, magnesium not only has the advantage of light weight, high strength, and a density similar to that of human bone, but also has good biocompatibility and promotes the growth of human bone. However, the mechanical properties and corrosion resistance of magnesium alloys need to be further improved to meet the requirements for human biodegradable implants. In this study, three alloys (mass fractions: Mg–10Zn, Mg–20Zn, and Mg–30Zn (wt.%)) were prepared using powder metallurgy by homogeneously mixing powders of the above materials in a certain amount with magnesium as the substrate through the addition of zinc elements, which also have good biocompatibility. The effect of zinc on the microstructure, mechanical properties, wear performance, and corrosion resistance of magnesium–zinc alloys was studied when the zinc content was different. The results show that compared with the traditional magnesium alloy using powder metallurgy, prepared magnesium alloy has good resistance to compression and bending, its maximum compressive stress can reach up to 318.96 MPa, the maximum bending strength reached 189.41 MPa, and can meet the mechanical properties of the alloy as a human bone-plate requirements. On the polarization curve, the maximum positive shift of corrosion potential of the specimens was 73 mv and the maximum decrease of corrosion-current density was 53.2%. From the comparison of the above properties, it was concluded that the three prepared alloys of which Mg–20% Zn had the best overall performance. Its maximum compressive stress, maximum bending strength, and corrosion-current density reached 318.96 MPa, 189.41 MPa and 2.08 × 10−5 A·cm−2 respectively, which are more suitable for use as human implant bone splints in human-body fluid environment.
The Structure of the Brachial Plexus of the Djungarian Hamster (Phodopus sungorus)
Authors: Grzeczka Arkadiusz , Zdun Maciej 
Published: January 2022

AbstractHamsters are often chosen as companion animals but are also a group of animals frequently subjected to laboratory tests. As there are no scientific publications providing information on the anatomical architecture of the brachial plexus of the Djungarian hamster, this study analyses the structure of this part of the nervous system of this species. It is important to know the details of this structure not only for cognitive reasons, but also due to the increasing clinical significance of rodents, which are often used in scientific research. The study was conducted on 55 specimens. Like in humans, the brachial plexus of the Djungarian hamster has three trunks. The following individual nerves innervating the thoracic limb of the Djungarian hamster: the radial nerve, median nerve, ulnar nerve, musculocutaneous nerve, axillary nerve, suprascapular nerve, thoracodorsal nerve, cranial pectoral nerves, caudal pectoral nerve, lateral thoracic nerve, long thoracic nerve, and subscapular nerves. Similarly to other mammals of this order, the brachial plexus of the Djungarian hamster ranges widely (C5-T1). However, its nerves are formed from different ventral branches of the spinal nerves than in other mammals.
Association of Vitamin D Status and COVID-19-Related Hospitalization and Mortality
Authors: Seal Karen H. , Bertenthal Daniel , Carey Evan , Grunfeld Carl , Bikle Daniel D. , Lu Chuanyi M. 
Published: January 2022

Abstract
Background
The relationship between vitamin D status and COVID-19-related clinical outcomes is controversial. Prior studies have been conducted in smaller, single-site, or homogeneous populations limiting adjustments for social determinants of health (race/ethnicity and poverty) common to both vitamin D deficiency and COVID-19 outcomes.

Objective
To evaluate the dose-response relationship between continuous 25(OH)D and risk for COVID-19-related hospitalization and mortality after adjusting for covariates associated with both vitamin D deficiency and COVID-19 outcomes.

Design
Retrospective cohort study.

Patients
Veteran patients receiving care in US Department of Veteran Affairs (VA) health care facilities with a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) test and a blood 25(OH)D test between February 20, 2020, and November 8, 2020, followed for up to 60 days.

Main Measures
Exposure was blood 25(OH)D concentration ascertained closest to and within 15 to 90 days preceding an index positive SARS-CoV-2 test. Co-primary study outcomes were COVID-19-related inpatient hospitalization requiring airborne, droplet, contact, or other isolation and mortality ascertained within 60 days of an index positive SARS-CoV-2 test.

Key Results
Of 4,599 veterans with a positive SARS-CoV-2 test, vitamin D deficiency (< 20 ng/mL) was identified in 665 (14.5%); 964 (21.0%) were hospitalized; and 340 (7.4%) died. After adjusting for all covariates, including race/ethnicity and poverty, there was a significant independent inverse dose-response relationship between increasing continuous 25(OH)D concentrations (from 15 to 60 ng/mL) and decreasing probability of COVID-19-related hospitalization (from 24.1 to 18.7%, p=0.009) and mortality (from 10.4 to 5.7%, p=0.001). In modeling 25(OH)D as a log-transformed continuous variable, the greatest risk for hospitalization and death was observed at lower 25(OH)D concentrations.

Conclusions
Continuous blood 25(OH)D concentrations are independently associated with COVID-19-related hospitalization and mortality in an inverse dose-response relationship in this large racially and ethnically diverse cohort of VA patients. Randomized controlled trials are needed to evaluate the impact of vitamin D supplementation on COVID-19-related outcomes.
Sample management: a primary critical starting point for successful omics studies
Authors: Koh Eun Jung , Kim Seung Hwan , Hwang Seung Yong 
Published: January 2022

AbstractBiological samples collected from cohort studies are widely utilized in molecular genetic studies and are typically stored long term for future applications, such as omics analyses. The extent of sample availability is determined by proper sample handling, and it is of primary importance for successful omics studies. However, questions on whether samples in long-term storage are properly available for omics experiments has been raised, because the quality and availability of such samples remain unknown until their actual utilization. In that perspective, several guidelines for proper sample management have been suggested. In addition, several researchers assessed how improper management damages sample using mock sample and suggested a set of requirements for sample handling. In this review, we present several considerations for sample handling eligible for omics studies. Focusing on birth cohorts, we describe the types of samples collected from which omics data were generated. This review ultimately aims to provide proper guidelines for sample handling for successful human omics studies.