bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recalibrating student affairs practice and preparation to graduate career‐ready citizen professionals
Authors: Moore Tami L. , Leffingwell Claire J. , Nelson Mark S. 
Published: May 2022

AbstractSince the origins of higher education in North America, interested parties have argued the role of colleges and universities. Some advance a public good argument for educating students as active citizens; others, from a private good stance, focusing on preparing graduates for employment. Moore, Leffingwell and Nelson suggest a hybrid purpose: preparing college graduates as leaders who are career‐ready and also oriented toward advancing the well‐being of their workplace, organization, or community. Achieving these goals, the authors argue, begins with ensuring that all educators who support student learning in and out of the classroom have been prepared with the skills, knowledge, and habits of mind that practitioners want students to learn during their college years. Therefore, the desired outcomes of recalibrating the CLDE agenda advanced in this volume must include consideration of student affairs professional practice and graduate preparation programs.
Now or later: Health impacts of delaying single‐dose HPV vaccine implementation in a high‐burden setting
Authors: Burger Emily A. , Laprise Jean‐François , Sy Stephen , Regan Mary Caroline , Prem Kiesha , Jit Mark , Brisson Marc , Kim Jane J. 
Published: May 2022

AbstractWe aimed to quantify the health impact of immediate introduction of a single‐dose human papillomavirus (HPV) vaccination program in a high‐burden setting, as waiting until forthcoming trials are completed to implement single‐dose HPV vaccination may result in health losses, particularly for cohorts who would age‐out of vaccination eligibility. Two mathematical models fitted to a high‐burden setting projected cervical cancer incidence rates associated with (a) immediate implementation of one‐dose HPV vaccination vs (b) waiting 5 years for evidence from randomized trials to determine if one‐ or two‐doses should be implemented. We conducted analyses assuming a single dose was either noninferior or inferior to two doses. The models projected that immediate implementation of a noninferior single‐dose vaccine led to a 7.2% to 9.6% increase in cancers averted between 2021 to 2120, compared to waiting 5 years. Health benefits remained greater with immediate implementation despite an inferior single‐dose efficacy (80%), but revaccination of one‐dose recipients became more important assuming vaccine waning. Under most circumstances, immediate vaccination avoided health losses for those aging out of vaccine eligibility, leading to greater health benefits than waiting for more information in 5 years.
Assessing barriers to the career ladder and professional development for ethnic minority genetic counselors in the United States
Authors: Baldwin Aaron , Berninger Taylor , Harrison Barbara , Ramos Erica , McGinniss Molly A. 
Published: May 2022

AbstractEthnic diversity is not reflected within healthcare professions, including genetic counseling, where lack of growth and membership among minority colleagues extends to upper‐level and executive roles. While diversity and inclusion‐based topics have been emphasized, studies on potential barriers to career advancement in the field of genetic counseling have not received the same attention. Our study examined the current state of mentorship and sponsorship programs, the presence of diversity and inclusion initiatives, and opportunities for career advancement through the lens of a minority genetic counselor. Practicing genetic counselors in the United States identifying as part of any racial group, other than non‐Hispanic White alone, were recruited through the Minority Genetics Professionals Network for survey participation. A 31‐item survey was fully completed by 19 practicing genetic counselors from a variety of ethnic backgrounds. Data were analyzed using descriptive statistics and thematic analysis, allowing for individual stories and accounts to be amplified. Results showed 16 of 19 participants had never been promoted in their current employment setting. Additionally, 7 out of 19 respondents disagreed or strongly disagreed that their company had a commitment to an ethnically diverse workforce within upper‐level positions. Prominent themes identified from open‐ended responses included lack of social connection with supervisors and the cross‐race effect, a term referencing a tendency for individuals to better recognize members of their own race or ethnicity than others. Additional themes revealed feelings of isolation, need for support from White colleagues, as well as desired emphasis on sponsorship tailored toward professional growth. These findings demonstrate a need for proactive involvement in reaching ethnic and racial minority genetic counselors through companywide policy efforts, support and advocacy from White colleagues, and modification of cultural perception frameworks. Further focus and emphasis on these distinct but critical topics may be important in promoting increased diversity in upper‐level positions in the field of genetic counseling.
Genetics providers’ experiences using telehealth: A grounded theory approach
Authors: Beretich Lauren A. , Sarasua Sara M. , DeLuca Jane M. 
Published: May 2022

AbstractThere was a paucity of research describing the perspectives and experiences of clinical genetics providers in telehealth prior to the SARS‐CoV‐2 pandemic. The available literature focused primarily on provider satisfaction and offered limited insight into genetics providers’ work in telehealth. The purpose of this study, conducted just prior to the widespread knowledge of SARS‐CoV‐2 in the United States and mass transition to telehealth, was to understand the telehealth process from the vantage of genetics providers working in telehealth practice settings. This research employed grounded theory using the constant comparative method in coding and analysis of data to generate theory. Ten genetics providers were interviewed over the phone about their experiences, specifically the efficacy of telehealth work, providers’ perspectives of patient outcomes, and personal fulfillment derived from telehealth patient care. Six themes emerged in the study: Making Professional Choices, Increasing Patient Access, Providing Effective Services, Understanding Telehealth Limits, Feelings about Telehealth Consultations, and Deepening Personal Fulfillment. These major themes guided the creation of the Theoretical Model of Telehealth Providers in Genetics, which depicts the connections between providers’ personal fulfillment in telehealth, commitment to patient services, and the provision of telehealth to the public. This model may help others who are working on telehealth initiatives or developing telehealth programs. Findings from this study can support the current use and the growth of telehealth in genetics as a result of the SARS‐CoV‐2 pandemic. Future research is needed to describe the telehealth process and develop valid instruments for assessing and measuring the constructs of the Theoretical Model of Telehealth Providers in Genetics.
Long‐term efficacy and safety of programmed death‐1 (PD‐1) antibody alone in relapsed/refractory human immunodeficiency virus‐associated Hodgkin lymphoma
Authors: Wang Chaoyu , Zhou Fanlin , Zhang Lingqian , Liu Tingting , Nan Yingyu , Liu Yao 
Published: May 2022

AbstractWe report a young patient initially diagnosed with human immunodeficiency virus (HIV)‐associated Hodgkin lymphoma (HL), and received six cycles of ABVD chemotherapy regimens and involvement field irradiation therapy. However, the disease progressed after two months later, and then received second line GDP regimen. Unfortunately, after five cycles of GDP, the patient progression disease (PD) again. The patient was then offered sintilimab alone. After 8 cycles, the patient received complete response (CR) and no 3/4 grade toxicity. Currently, at a follow‐up period of four years, he is still alive with CR and no lymphoma‐related symptoms. This case demonstrates the feasibility of sintilimab antibody in relapsed/refractory HIV‐associated Hodgkin lymphoma.
Comparing Survival Outcomes of Patients With LI‐RADS‐M Hepatocellular Carcinomas and Intrahepatic Cholangiocarcinomas
Authors: Kierans Andrea S. , Lafata Kyle J. , Ludwig Daniel R. , Burke Lauren M. B. , Chernyak Victoria , Fowler Kathryn J. , Fraum Tyler J. , McGinty Katrina A. , McInnes Matthew D. F. , Mendiratta‐Lala Mishal , Cunha Guilherme Moura , Allen Brian C. , Hecht Elizabeth M. , Jaffe Tracy A. , Kalisz Kevin R. , Ranathunga Damithri S. , Wildman‐Tobriner Benjamin , Cardona Diana M. , Aslam Anum , Gaur Sonia , Bashir Mustafa R. 
Published: May 2022

BackgroundThere is a sparsity of data evaluating outcomes of patients with Liver Imaging Reporting and Data System (LI‐RADS) (LR)‐M lesions.PurposeTo compare overall survival (OS) and progression free survival (PFS) between hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA) meeting LR‐M criteria and to evaluate factors associated with prognosis.Study TypeRetrospective.SubjectsPatients at risk for HCC with at least one LR‐M lesion with histologic diagnosis, from 8 academic centers, yielding 120 patients with 120 LR‐M lesions (84 men [mean age 62 years] and 36 women [mean age 66 years]).Field Strength/SequenceA 1.5 and 3.0 T/3D T1‐weighted gradient echo, T2‐weighted fast spin‐echo.AssessmentThe imaging categorization of each lesion as LR‐M was made clinically by a single radiologist at each site and patient outcome measures were collected.Statistical TestsOS, PFS, and potential independent predictors were evaluated by Kaplan–Meier method, log‐rank test, and Cox proportional hazard model. A P value of <0.05 was considered significant.ResultsA total of 120 patients with 120 LR‐M lesions were included; on histology 65 were HCC and 55 were iCCA. There was similar median OS for patients with LR‐M HCC compared to patients with iCCA (738 days vs. 769 days, P = 0.576). There were no significant differences between patients with HCC and iCCA in terms of sex (47:18 vs. 37:18, P = 0.549), age (63.0 ± 8.4 vs. 63.4 ± 7.8, P = 0.847), etiology of liver disease (P = 0.202), presence of cirrhosis (100% vs. 100%, P = 1.000), tumor size (4.73 ± 3.28 vs. 4.75 ± 2.58, P = 0.980), method of lesion histologic diagnosis (P = 0.646), and proportion of patients who underwent locoregional therapy (60.0% vs. 38.2%, P = 0.100) or surgery (134.8 ± 165.5 vs. 142.5 ± 205.6, P = 0.913). Using multivariable analysis, nonsurgical compared to surgical management (HR, 4.58), larger tumor size (HR, 1.19), and higher MELD score (HR, 1.12) were independently associated with worse OS.Data ConclusionThere was similar OS in patients with LR‐M HCC and LR‐M iCCA, suggesting that LR‐M imaging features may more closely reflect patient outcomes than histology.Evidence Level3Technical EfficacyStage 5
The Orinoco low‐level jet during El Niño–Southern Oscillation
Authors: Builes‐Jaramillo Alejandro , Yepes Johanna , Salas Hernán D. 
Published: May 2022

AbstractThis study shows the influence of El Niño–Southern Oscillation (ENSO) over the seasonal and diurnal variability of the Orinoco low‐level jet (OLLJ) during the December–January–February (DJF) season. Results show changes in the occurrence and intensity of the OLLJ winds during the phases of ENSO (El Niño and La Niña) in relation to Neutral conditions. During El Niño (La Niña), the OLLJ days decrease (increase) over the mid and exit of the OLLJ corridor. Furthermore, the mean wind vertical profiles (and the intensity of the diurnal cycle) decrease (increase) with values ranging from 5 to 9 m·s−1. We highlight that the OLLJ days decrease (increase) in January (February) during El Niño (La Niña) up to 24% (15%). These changes are modulated by the pressure gradient between the Atlantic subtropical high and the near‐equatorial trough regions that decreases (increases) during El Niño (La Niña) and thus induces a decrease (increase) of the OLLJ winds. Moreover, the water vapour flux and precipitation reduce during both phases of ENSO along the OLLJ corridor. This work shows new insights on the OLLJ features during ENSO, which contributes to improving our understanding of the processes that influence the hydro‐climatology of northern South America.
The role of cultural innovation in the success of luxury startups
Authors: Serdari Thomaï 
Published: May 2022

AbstractLuxury startups' sensibility to the social and cultural environment is the dimension that in addition to the technical and strategic excellence and pricing strategy ensure the firms' long‐term success. Incorporating a humanities approach and design theory in the study of business challenges leads to articulated solutions. Luxury that is enduring, addresses the customer on a cognitive level and not solely on an emotional or physical one. A response to a startup's cultural context is the key to achieving internal consistency and (external) resonance with the consumers.
Using employee‐generated content from digital platforms to understand the luxury culture
Authors: Castillo Jhon Alvarez , Bryson Douglas , Divakaran Pradeep Kumar Ponnamma , Xiong Jie 
Published: May 2022

AbstractAs perceived by company employees, luxury culture is best understood by collecting and analyzing anonymous genuine current or past employee‐generated comments (EGCs) about their experience of specific work culture, without fear of retaliation by using digital platforms. This paper focuses on luxury culture, including organizational culture, founder culture, and country‐of‐origin culture. It examines the employee‐perception of organizational culture in the case of L'Oréal, a luxury cosmetics company, by analyzing EGCs collected from a digital platform. This study demonstrates that sentiment analysis methodology is a valuable technique in understanding how employees' perceptions of luxury companies' cultures and significantly that changes happening in luxury brands' dynamic organizational cultures may well be known relatively early by analyzing the EGCs. This study adds a new factor to the luxury organizational culture called “digital culture,” in addition to the previously identified cultural determinants, including collective, emotional, historical, symbolic, dynamic, and diffuse dimensions.
Accounting for residual heterogeneity in double‐observer sightability models decreases bias in burro abundance estimates
Authors: Hennig Jacob D. , Schoenecker Kathryn A. , Cain James W. , Roemer Gary W. , Laake Jeffrey L. 
Published: May 2022

AbstractFeral burros (Equus asinus) and horses (E. ferus caballus) inhabiting public land in the western United States are intended to be managed at population levels established to promote a thriving, natural ecological balance. Double‐observer sightability (MDS) models, which use detection records from multiple observers and sighting covariates, perform well for estimating feral horse abundances, but their effectiveness for use in burro populations is less understood. These MDSmodels help minimize detection bias, yet bias can be further reduced with models that account for unmodeled variation, or residual heterogeneity, in detection probability. In populations containing radio‐marked individuals, residual heterogeneity can be estimated with MDSmodels by including a covariate that corresponds to the marked status of a group (MHmodels). Another approach is to use information from detections missed by both observers to account for the characteristics that make groups more or less likely to be detected, or recaptured, by the second observer (MRmodels). We used aerial survey data from 3 burro populations (Sinbad Herd Management Area, UT [2016–2018], Lake Pleasant Herd Management Area, AZ [2017], and Fort Irwin National Training Center, CA [2016–2017]) to develop MDSmodels applicable for feral burros in the southwestern United States. Our objectives were to quantify precision and bias of standard MDSsurveys for feral burros and to examine which model type for incorporating residual heterogeneity (MHor MR) would result in the least‐biased estimates of burro populations relative to the minimum number known alive (MNKA) within the Sinbad Herd Management Area. Standard MDSmodel estimates achieved a mean coefficient of variation of 0.08, while underestimating MNKA by an average of 27.1%. Accounting for residual heterogeneity through recapture probability in MRmodels resulted in estimates closer to MNKA than MHmodels (9.5% vs. 16.5% less than MNKA). Our results indicate that MDSmodels can achieve precise enough estimates to monitor feral burro populations, but they routinely produce negatively biased estimates. We encourage the use of radio‐collars to reduce bias in future burro surveys by accounting for residual heterogeneity through MRmodels.
Second primary squamous cell carcinomas treated with trans oral robotic surgery: Oncological and functional results
Authors: Soldati Federico , Lambercy Karma , Simon Christian 
Published: May 2022

AbstractBackgroundRecovery of swallowing in patients treated with trans‐oral robotic surgery (TORS) is in general considered as favorable. However, patients afflicted with a secondary primary carcinoma of the head and neck may be more vulnerable to swallowing dysfunctions after trans‐oral surgery as a consequence of previous treatments.MethodsThis is a retrospective monocentric study on patients undergoing TORS for second primary squamous cell carcinoma between 2013 and 2017 (follow‐up until June 2021). Swallowing performance was assessed via the functional outcome swallowing scale (FOSS). Also, overall survival (OS), disease‐free survival (DS) and disease‐specific survival (DSS) were evaluated.ResultsEighteen patients (median 62 years) underwent TORS with curative intent for T1‐2 oropharyngeal and supraglottic secondary primaries. The average follow‐up was of 52 months. All cases were resected R0 using TORS. 84% of patients had a post‐treatment FOSS score equal or better upon last follow‐up compared with pre‐treatment. Only one patient required a percutaneous gastrostomy long term. DSS/DFS/OS at 5 years was 94%, 60%, and 67%, respectively. The main cause of death was metachronous pulmonary neoplasia.ConclusionsOur study demonstrates encouraging results in terms of swallowing recovery in patients undergoing TORS for selected secondary primaries of the oropharynx and supraglottic larynx. Further studies into trans‐oral surgery for this condition seem therefore warranted.Level of Evidence: Case series; Level 4.
A trait‐based carbon export model for mesopelagic fishes in the Gulf of Mexico with consideration of asynchronous vertical migration, flux boundaries, and feeding guilds
Authors: Woodstock Matthew S. , Sutton Tracey T. , Zhang Yuying 
Published: May 2022

AbstractFish‐mediated carbon export provides a significant proportion of the biological carbon pump in oligotrophic regions. Bioenergetic models estimate this carbon transport, but many lack species‐specific traits and no carbon export model has been developed in the mesopelagic Gulf of Mexico. Intensive mesopelagic sampling efforts in the northern and eastern Gulf of Mexico have provided high‐resolution information regarding community composition, species' vertical migratory characteristics, diel depth occupancies, and diets. A stochastic, individual‐based model was developed for deep‐pelagic fishes in the northern Gulf of Mexico to estimate bioenergetic rates and carbon export fluxes. Fishes that ate gelatinous zooplankton consumed more mass per body weight per day than predators of cephalopods and fishes, ostensibly to increase the throughput of prey with less carbon (gelata) or more refractory materials (Crustacea). A dynamic energy budget submodel indicated that during 81% of occurrences, asynchronous vertically migrating fishes rested for 1 d before migrating again, but migrations on successive days were possible. In terms of carbon export, myctophids and stomiids contributed greater than 53% and 12% of the active carbon flux for the entire assemblage in all scenarios. The assemblage‐wide carbon export rate driven by vertically migrating fishes was 0.14–0.72 mg C m−2 d−1, 61% of the ingested carbon by the assemblage. Incorporating species‐specific traits and individual variability in bioenergetic models allows for more complex research questions (e.g., the effect of feeding guilds and asynchronous migration on carbon export) compared to the carbon export models that otherwise assume all fishes within a functional group are equivalent.
The detection of bacterial exometabolites in marine dissolved organic matter through ultrahigh‐resolution mass spectrometry
Authors: Bercovici Sarah K. , Dittmar Thorsten , Niggemann Jutta 
Published: May 2022

AbstractBacteria play a key role in sustaining the chemodiversity of marine dissolved organic matter (DOM), yet there is limited direct evidence of a major contribution of bacterial exometabolites to the DOM pool. This study tests whether molecular formulae of intact exometabolites can be detected in natural DOM via untargeted Fourier‐transform ion cyclotron resonance mass spectrometry (FT‐ICR‐MS). We analyzed a series of quantitative mixtures of solid‐phase extracted DOM from the deep ocean, of a natural microbial community and selected model strains of marine bacteria. Under standard instrument settings (200 broadband scans, mass range 92–1000 Da), 77% of molecular formulae were shared between the mesocosm and marine DOM. However, there was < 10% overlap between pure bacterial exometabolome with marine DOM, and in mixing ratios closest to mimicking natural environments (1% bacterial DOM, 99% marine DOM), only 4% of the unique bacterial exometabolites remained detectable. Further experiments with the bacterial exometabolome DOM mixtures using enhanced instrument settings resulted in increased detection of the exometabolites at low concentrations. At 1000 and 10,000 accumulated scans, 23% and 29% of the unique molecular formulae were detectable at low concentrations, respectively. Moreover, windowing a specific mass range encompassing a representative fraction of exometabolites tripled the number of unique detected formulae at low concentrations. Routine FT‐ICR‐MS settings are thus not always sufficient to distinguish bacterial exometabolome patterns from a seawater DOM background. To observe these patterns at higher sensitivity, we recommend a high scan number coupled with windowing a characteristic region of the molecular fingerprint.
Influence of corrosion behavior of X80 steel in silty soil containing composite sodium salt based on orthogonal test
Authors: Wang Yuting , Han Pengju , Sun Funan , Xie Ruizhen , Bai Xiangling , He Bin , Wang Xiaoyuan 
Published: May 2022

AbstractThe corrosion law of X80 steel in silty soils with different contents of sodium chloride and sodium sulfate is studied at different temperatures by using an orthogonal test group of three factors and three levels L9 (34) in conjunction with the results of electrochemical impedance spectroscopy, polarization curve, and microscopic images. The steel corrosion rate increases with the silty soil temperature. The presence of SO42− in silty soil inhibits corrosion in X80 steel. The corrosion mechanism involves competition between Cl− and SO42− for adsorption sites: SO42− ions occupy some corrosion pits, and FeS and other corrosion products are generated and adhere to the surface of the corrosion pits, inhibiting further reaction. A range analysis of the fitted electrochemical impedance spectra and polarization curves of X80 steel shows that the temperature has the strongest effect on the corrosion of X80 steel, followed by the Cl− content, whereas the SO42− content has the least effect. The lowest corrosion rate is found for a silty soil Cl− content of 0.3%, a SO42− content of 2.0%, and a temperature of −20°C.