bluuebunny/crossref_metadata_2025_split huggingface dataset:
« Circulez, y’a rien à voir ! »… ou quand le discours institutionnel se fige dans une relation de soin pathogène
Authors: Boucherat-Hue Valérie , Hulin Adeline 
Published: January 2022

Ariane, âgée de 45 ans, est en foyer d’hébergement depuis 7 ans. Sa vie est marquée par des relations complexes et parfois étranges. L’équipe éducative rencontre des difficultés de communication et des moments d’errance diagnostique face au « cas clinique » d’Ariane. Écartelée entre une étiquette diagnostique de déficit intellectuel et une représentation psychanalytique d’hystérie, l’équipe éducative est perplexe, d’autant plus qu’au décès de sa grand-mère, Ariane entre dans un deuil pathologique qui s’associe à l’apparition de symptômes somatiques. De même, les discours entre les institutions – d’hébergement et de soins – et les équipes – éducatives et médicales – débouchent sur des paradoxes qui entravent la pensée et des clivages de fonctionnement générant une communication difficile entre eux. Cependant, suite à un travail mené par la psychologue du service sur le déni institutionnel concernant la pathologie d’Ariane, une circulation des émotions puis une amorce de réflexion commune fera de nouveau surface en retissant des liens. La parole apparaît ici comme opérateur de changements, où un nouvel accompagnement est proposé à Ariane par les équipes, permettant à cette dernière d’amorcer un travail sur sa souffrance psychique.
Emprunts de mots, écriture de soi
Authors: Cabot Florence , Gribos Aurore 
Published: January 2022

Dans le contexte carcéral, la demande de soins psychiques faite par les personnes détenues issues de l’étranger est avant tout celle d’un soutien. Comment accueillir et penser la prise en charge de ces personnes isolées ? Comment dépasser la barrière de la langue sans nier la singularité de chacun ? Quel travail thérapeutique est possible ?L’expérience présentée a consisté à mettre en place un groupe d’écriture constitué de personnes détenues originaires de pays de l’est de l’Europe. La proposition a émergé de l’hypothèse que, malgré les différences culturelles et les antagonismes potentiels entre les membres pressentis, les processus groupaux pourraient favoriser la réduction de l’écart entre le sentiment d’isolement et le sentiment d’appartenance à un collectif pour réanimer la vie psychique individuelle. L’écriture a été envisagée comme médiatrice, c’est-à-dire comme un tiers proposant les ressources nécessaires pour créer une circulation entre le groupal et le subjectif, faire émerger et mettre au travail la question de l’attachement.
L’annonce d’une mauvaise nouvelle à un patient : méthodologie de l’analyse multimodale d’un corpus de formation
Authors: Saubesty Jorane , Tellier Marion , Francon Daniel 
Published: January 2022

À travers notre étude, nous proposons une analyse linguistique des interactions patient/médecin en situation de formation à l’annonce d’événement indésirable grave (EIG). Nous nous plaçons dans le cadre de la linguistique interactionnelle, laquelle a pour objectif d’étudier les structures et les usages de la langue, en interaction et dans son environnement naturel (Selting et Couper-Kuhlen, 2001 : 1). Nous adoptons également une perspective multimodale, à savoir que nous considérons la parole comme un tout composé de vocalisations, de gesticulations, d’expressions faciales, etc. (McNeill, 1992). Partant du constat de Lausberg et Sloetjes (2009) selon lequel la méthodologie employée pour la catégorisation gestuelle, notamment, n’est souvent pas clairement définie et reste opaque, nous souhaitons exposer le schéma d’annotation utilisé dans notre étude de façon claire et précise. Ce schéma s’articule autour de deux notions interactionnelles que sont les séquences de réparation et les feedbacks et des différentes modalités langagières.
Démêler les souvenirs du patient en consultation Alzheimer
Authors: Ortiz Caria Alexandra 
Published: January 2022

En consultation Alzheimer, le médecin évalue le patient notamment par sa capacité à (se) rappeler l’actualité notable ou récente, référence supposée partagée. Dans la perspective de l’Analyse de Conversation nous décrivons le travail collaboratif et continu de choix lexicaux et de sélections thématiques accompli. Si le patient reconnait l’existence d’événements, il présente des difficultés à les dire et donc à produire la « bonne » réponse. Quand démêler des souvenirs sur un thème affecte le patient, privilégiant ses besoins socio-émotionnels, le médecin interrompt le test sinon il persévère dans son agenda clinique à-toutes-fins-diagnostiques. Il propose alors une amorce, puis des relances thématiques simplifiées jusqu’à la tentative référentielle indiquant par un dispositif de reconnaissance le thème attendu. Ces réparations prolongent la temporalité du test tout en en complexifiant l’organisation et donne un éclairage du travail d’ajustement mutuel réalisé.
The Communist party and informal groups in ukraine during perestroika (1985-1989): An unambiguous relationship?
Authors: Merlo Simona 
Published: January 2022

The essay, mainly based on first-hand documents from the Central Committee of the Communist party of Ukraine, strives to offer a new reading of the relationships between “informal groups” and Soviet power in Ukraine during perestroika, paying attention to the different regional contexts. Its aim is not only to look at how the leadership of the Communist party of Ukraine viewed a phenomenon that could destabilize the system’s equilibrium. It also wants to show how the party itself proved permeable to the changes triggered by the emergence of informal groups. This fact explains why the party feared not only the destabilizing potential represented by the appearance of such a new element, but above all the attraction it generated inside some circles of the party itself. In this phase of perestroika – between the end of 1985 and March 1989 – the importance of neformaly did not lie in the fact that they represented an organized opposition, but rather in that they shed light on the political crisis in institutions, organizations and personalities that were a fundamental part of the Soviet system.
Spécificités des entreprises de défense et processus d’innovation : une approche empirique par les références scientifiques contenues dans les brevets
Authors: Fauconnet Cécile 
Published: January 2022

Cet article questionne le processus d’innovation des entreprises de défense sous l’angle spécifique de l’intégration de connaissances scientifiques. Alors que les analyses de la contribution de la science à l’innovation technologique se concentrent majoritairement sur les industries des biotechnologies, de la pharmacie et des semi-conducteurs, notre article propose une approche originale en traitant des entreprises participant au marché de défense. En mobilisant les données de brevets de non-patent literature de 1 722 entreprises innovantes entre 2010 et 2016, cet article montre que l’activité de défense influence négativement l’intégration de connaissances scientifiques dans les innovations technologiques des entreprises.Classification JEL : L64, 033, L16.
Effets des réseaux de télémédecine sur la durée de séjour et l’intensité des transferts des patients : application au réseau Périn@t à l’aide d’un modèle de durée à population séparée à effet aléatoire
Authors: Nassiri Nabil , Nassiri Abdelhak 
Published: January 2022

Cette étude met en évidence les effets des réseaux de télémédecine sur la durée de séjour et la fréquence de transfert des patients. Nous retenons l’expérience naturelle du réseau Périn@t en obstétrique et appliquons trois modèles économétriques aux données de six maternités bretonnes en 2004 : les modèles Logit, de Cox et de durée à population séparée à effet aléatoire. Les résultats montrent que la coopération dans ce réseau permet de réduire la fréquence des transferts et de décider les transferts rapidement dès les premiers jours d’admission. Nous remarquons aussi que les maternités pratiquent bien les stratégies de surdiagnostic de l’état de sévérité des parturientes pour augmenter la fréquence des transferts.L’inflation des transferts est un effet contre-productif du financement à l’acte. Aucun système de financement ne permet une gestion efficace ni une pratique optimale des transferts. Nos résultats empiriques montrent que les réseaux de télémédecine constituent un mécanisme pertinent.Classification JEL : C34, C51, I11, I18.
Properties of rice husk ash silica filled natural rubber and acrylonitrile-butadiene rubber blends
Authors: Wijesinghe H. G. I. M. , Etampawala T. N. B. , Edirisinghe D. G. , Gamlath G. R. V. S. , Wadugodapitiya R. R. W. M. U. G. K. , Bandara T. A. R. W. M. M. C. G. 
Published: January 2022

Purpose: Rice husk is burnt and discarded without effective use; however, it is a reliable resource that can be used to extract silica from its ash (RHAS) and can be incorporated in rubber blends as filler. The effect of Natural rubber (NR) and Acrylonitrile-butadiene rubber (NBR) ratio of NR/NBR blends filled with RHAS on physico-mechanical, and swelling percentage in specific oils (brake oil, hydraulic oil, engine oil) and toluene were studied since these blends have potential applications like fluid sealing. Method: RHAS was extracted via sol-gel method and characterized using X-ray diffraction (XRD), Fourier Transform Infrared Spectroscopic (FTIR), and Scanning Electron Microscopic (SEM) analyses. NR/NBR blends with different NR to NBR ratios (100:0, 80:20, 60:40, 40:60, 20:80, 0:100) were prepared by incorporating 25 parts per hundred parts of rubber and curing characteristics, physico-mechanical and swelling properties were evaluated. Findings: The XRD, FTIR, and SEM analyses confirmed that the RHAS contains silica with a combination of nanoparticles and large agglomerates. The blends showed preferable curing characteristics while the hardness, compression set, and tear strength of blends ranged from 60-70 International Rubber Hardness Degrees, 0.5-6%, and 10-20 N/mm, respectively. Although the tensile properties (before ageing) were low, the retention of tensile strength after ageing was better in NR/NBR blends. Blends with high NBR proportion showed tolerable swelling against toluene, hydraulic oil, and engine oil while blends with low NBR proportion showed better swelling resistance to brake oil. Limitation: Time was limited to evaluate the properties of blends with different loading levels of RHAS. Value: There is a potential to use these NR/NBR blends in applications like fluid seals which require oil resistance and toluene resistance, where 0.5-6% and about 60-100% swellings are tolerable, respectively, compromising the physico-mechanical properties meanwhile replacing carbon black in respective applications.
Ameliorative role of potassium on water relations, antioxidative enzymes and yield of sweet corn genotypes under water deficit
Authors: Rao S. , Singh S. , Singh N. 
Published: January 2022

Purpose: In recent years, it has been revealed that potassium delivers drought stress tolerance in many crops. This nutrient is not yet tested for sweetcorn. Therefore, this study investigated the impact of drought and soil applied potassium on water relations, antioxidant enzymes and yield attributes of two sweet corn genotypes in India. Research Method: The factorial experiment was set-up with 5 replications in complete randomized block design. Factor one comprised of two genotypes (Sugar-75 and NSC 901B), factor two had six different water treatments and factor three with two different potassium levels. This investigation was designed with two genotypes of sweet corn to study the interaction between various water deficit conditions and soil applied potassium. Findings: Drought stress significantly decreased the water potential, osmotic potentialand relative water content and caused osmotic stress in sweet corn plants. Antioxidant enzymes activities were found to be up-regulated under drought stress while yield attributes were adversely affected by water deficit. Application of potassium increased the adaptation to water deficit stress by positively modulating the tested parameters. Results procured from this study suggested that exogenously applied potassium mitigated the drought mediated constrains on sweet corn and enhanced drought tolerance. Research limitation: The experiments were carried out in polythene pots to provide a uniform soil condition which was the main limitation when compared to field trials. Originality/value: Results of this experiment revealed that exogenous application of potassium can alleviate the damaging effect of drought stress on sweet corn. However, more research on other crops is needed to ensure its long-term sustainability.
Neoadjuvant chemoradiotherapy followed by surgery for operable carcinoma esophagus
Authors: Dora Tapas Kumar , Aeron Tushar , Chatterjee Abhishek , Deshmukh Jayashree , Goel Alok , Bose Shubhadeep , Chaudhary Debashish , Sharma Rakesh , Khandelwal Sachin , Sancheti Sankalp , Pahwa Shefali , Singh Avtar , Saini Amit , Laskar Sarbani Ghosh , Agarwal Jai Prakash , Shrivastava Shyam Kishore , Kapoor Rakesh 
Published: January 2022

Background:
Carcinoma of the esophagus and gastroesophageal junction is an aggressive disease with limited survival. Standard management consists of multimodality therapy, incorporating chemotherapy, radiation, and surgery.

Objectives:
We aimed to understand the obstacles in treating patients with resectable esophageal cancer with neoadjuvant chemoradiotherapy followed by surgery. We also assessed the disease outcomes in the patients who completed surgery.

Materials and Methods:
We included patients with resectable esophageal carcinoma who received neoadjuvant chemoradiation between March 2017 and August 2019 at the Homi Bhabha Cancer Hospital in Sangrur, Punjab, a tertiary care center in rural India. As surgery for esophageal cancer was not performed at our center, patients had to be referred to a higher center for this. Patients were divided into two groups, based on the therapy they received following neoadjuvant chemoradiation: those who completed surgery (Group A) and those who did not (Group B). The pathologic response rates were noted. The disease-free survival (DFS) and overall survival (OS) were compared between the two groups.

Results:
A total of 55 patients (32 in Group A and 23 in Group B) were included the study. In Group A, complete pathologic responses were noted in 19 (59.4%), partial responses in 11 (34.4%) and poor responses in 2 (6.2%) patients. The major reasons for not undergoing surgery were patient refusal as they were feeling better after chemoradiation (8, 34.8%) and the presence of advanced inoperable (5, 21.7%) or metastatic disease (3, 13%) on imaging after chemoradiation. The median DFS in Group A and Group B was 8 months (range, 0–38 months) and 14 months (range, 0–29 months), respectively, and the 2-year DFS was 57.8% and 73.3%, respectively (P = 0.28). Median OS in Group A and Group B was 17 months (range, 3–43 months) and 17 months (range, 2–31 months), respectively, and the 2-year OS was 52.6% and 53.5%, respectively (P = 0.70).

Conclusions:
Implementing neoadjuvant chemoradiation followed by surgery for resectable esophageal cancer in a center where esophageal cancer surgery cannot be performed is challenging. Among patients who undergo surgery following neoadjuvant chemoradiation, complete pathologic responses occur in 59.4% patients, and clinical outcomes appear to be similar to those reported in the literature.
A multicenter, double-blind, randomized phase III trial of ramucirumab plus docetaxel versus placebo plus docetaxel for treatment of Stage IV non-small cell lung cancer after disease progression on or after platinum-based therapy (REVEL)
Authors: Prabhash Kumar , Doval D. C. , Rangarajan Bharath , Somani Naresh , Pruthi Aarohan , D’yachkova Yulia , Puri Tarun 
Published: January 2022

Background:
Ramucirumab plus docetaxel has been shown to improve survival as a second-line treatment for patients with Stage IV non-small-cell lung cancer (NSCLC) in the multicenter, double-blind, randomized, Phase III trial, REVEL.

Objective:
In this exploratory analysis, we aimed to assess the safety and efficacy of ramucirumab plus docetaxel in the Indian patient subgroup of the REVEL study.

Materials and Methods:
Adult patients with histologically or cytologically confirmed NSCLC of either squamous or non-squamous histology, who progressed during or after first-line platinum-based chemotherapy were randomized to receive either ramucirumab plus docetaxel or placebo plus docetaxel. We performed a descriptive analysis of the baseline characteristics, safety, and efficacy of the Indian subgroup of the overall REVEL study (NCT01168973). The analyses presented here are not intended for comparison purposes either between treatment arms or to the overall REVEL study.

Results:
Fifty-five Indian patients were included in the REVEL study. Baseline characteristics and prior therapies of these patients were well-balanced between the treatment arms. Almost 80% patients had non-squamous histology, and 78.2% were men. All patients had received prior standard platinum-based therapy: 25.5% of patients received maintenance, while 18.2% received taxane (paclitaxel only) as part of their first-line therapy. The incidence of treatment-emergent adverse events regardless of grade was similar between the two arms in the Indian safety subgroup. Patients treated with ramucirumab plus docetaxel experienced a median overall survival (OS) of 13.5 months (95% confidence interval [CI], 5.7–17.6) and progression-free survival (PFS) of 5.6 months (95% CI, 2.8–7.0) relative to a median OS of 5.3 months (95% CI: 3.6–9.9) and PFS of 1.5 months (95% CI: 1.3–5.2), for those treated with placebo plus docetaxel.

Conclusion:
In this exploratory analysis, Indian patients enrolled in the REVEL study demonstrated prolonged OS and PFS when treated with ramucirumab plus docetaxel, consistent with the overall results of the REVEL study. Ramucirumab plus docetaxel appears to be well tolerated by Indian patients, as the rates for most adverse events were similar with and without ramucirumab.
The utility of day 14 bone marrow response assessment in patients undergoing acute myeloid leukemia induction
Authors: Manuprasad Avaronnan , Raghavan Vineetha , Shenoy Praveen Kumar , Krishnan Aswathi , Nair Chandran K. 
Published: January 2022

Background:
Examination of the bone marrow on day 14 of induction chemotherapy for acute myeloid leukemia (AML) is a common practice. However, the evidence for re-inducing the patient based on early bone marrow response is limited.

Objectives:
This study was aimed at assessing the utility of bone marrow examination on day 14 of AML induction in predicting complete remission (CR) or residual disease and its impact on clinical decisions on re-induction in a resource-limited setting.

Materials and Methods:
This retrospective study was conducted at the Malabar Cancer Center, a tertiary cancer center in Kerala, India. Adult patients with AML who received 3 + 7 (daunorubicin + cytarabine) induction chemotherapy from January 2011 to December 2018 and underwent an early bone marrow examination on day 14 were included in the study. Early marrow response was considered adequate if the marrow cellularity was less than 15%–20%, with less than 5%–10% blasts. Patients with inadequate bone marrow response were given re-induction chemotherapy, if eligible. Unfit patients were continued on supportive measures. The end-of-induction bone marrow was done on day 28 after count recovery. Case records of all patients were reviewed, and data including the baseline characteristics, day 14 bone marrow response, and post-induction marrow status were collected.

Results:
Of the 96 patients who received induction chemotherapy during the study period, 78 underwent day 14 bone marrow assessment. The median age was 44 years (range, 15-66), and 43% of the patients were males. On day 14, 57 (73%) patients had adequate bone marrow response, 19 (24%) had inadequate response, and 2 (3%) had inconclusive results. Among the patients with inadequate responses, 12 attained CR at the end of induction, although only 9 received re-induction. Adequate day 14 bone marrow had a sensitivity of 89.8% (95% confidence interval [CI], 79–96) in predicting the remission status at the end of induction. The specificity of inadequate day 14 marrow response in predicting residual disease in post-induction bone marrow was 89% (95% CI, 79–96). Similarly, the positive predictive value was 100% and the negative predictive value was 14%.

Conclusion:
Although assessment of day 14 bone marrow response is useful in predicting the chances of CR at the end of induction, its role in guiding the decision for re-induction is doubtful, and larger studies are needed to address this question.
Considerations in laparoscopic resection of giant pancreatic cystic neoplasms
Authors: Gadiyaram Srikanth , Nachiappan Murugappan , Thota Ravi Kiran 
Published: January 2022

Background:
Laparoscopic distal pancreatectomy (LDP) with (LDPS) or without splenectomy for cystic tumours in the body and tail has become the standard of care. Data on patients with large tumours of the body and tail of the pancreas are sparse.

Patients and Methods:
A retrospective analysis of a prospectively maintained database of patients who were managed with laparoscopic surgery for pancreatic cystic neoplasm since 2010 was done. Patients with cysts more than 8 cm were analysed. Clinical presentation, imaging, details of the surgical procedure and the outcomes were looked into.

Results:
Five patients of giant pancreatic cystic neoplasm (GPCN) were managed with LDPS. Four patients were female, mean age was 45 years (range 15–69 years). The mean cyst size was 11.2 cms (range 8–15 cm). The splenic vein was either stretched or thrombosed in all patients. Three patients had sinistral portal hypertension. All patients were operated with a modified five-port placement. None of the patients required conversion. Mean operative duration was 3½ h, blood loss was 80 ml approximately and none required a blood transfusion. One patient had a biochemical leak. All patients were discharged from the hospital by 3rd postoperative day. Drain removal was done before discharge except in the patient with biochemical leak (removed on day 6). On a median follow-up of 89 months (range 1–120 months), two patients developed diabetes. There has been no Overwhelming post-splenectomy infections (OPSI).

Conclusion:
Laparoscopic distal pancreatectomy is feasible in patients with GPCN and offers the all the short-term benefits, namely lesser pain, no wound infections, early return of bowel activity, early return to orals and early discharge and early return to work. Splenectomy was required in all patients because of splenic vein thrombosis and portal hypertension in three and for technical reasons in the rest.