bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using simulation to improve confidence in the escalation of patients with learning disabilities by nurses in the acute care setting
Authors: Van Den Tooren Harriet , Kasfiki Eirini , Blackmore Andrew , Wright David 
Published: November 2022

The National Early Warning Score (NEWS) is used to collate measurements of patients’ vital functions, identifying patients who require management to prevent deterioration [1]. Not following NEWS escalation protocols is linked to adverse events and may occur due to prioritising clinical judgement over scores and communication failures [2]. Patients with learning disabilities are even more at risk of avoidable adverse events in hospital, but education to improve the understanding of the needs of these patients may be a protection against this [3]. This research assessed the improved confidence of nurses in escalation following a simulation-based course focused on escalating an unwell patient with learning difficulties.
The course started with an interactive talk on how to measure NEWS by a nurse educator. A simulation-based video we created of a mismanaged scenario involving a patient with learning disabilities was shown, followed by a discussion about handover using the SBAR structure. The simulation required the attendee accurately calculating a NEWS score of an actor connected to a monitor we could control and escalate to a doctor over the phone. This simulation was shown in real time to the other attendees, and the debriefing was facilitated by a doctor trained in debriefing. Pre- and post-course questionnaires were completed by attendees to assess their nursing experience, confidence in assessing NEWS, and escalation rated on a scale of 0 (very unconfident) to 5 (very confident).
The course was run 6 times for a total of 26 nurses. The median length of nursing experience was 17 months (range 1–249months). More attendees were confident (defined as 4 or 5 out of 5 in the confidence scale) in assessing NEWS, escalating to the medical team, and using SBAR post-course (96%, 96%, and 93% respectively) compared to pre-course (68%, 57%, and 54% respectively), which can be seen in
Confidence of the participating nurses before and after the course.
This simulation-based course focusing on care of a patient with learning disabilities has improved confidence in assessing NEWS and escalation with a structured handover to the medical team. Further research should be focused on multidisciplinary simulation on escalation in the acute care setting, and how including cases involving learning disabilities improves outcomes in this at-risk group.
1. Royal College of Physicians. National Early Warning Score (NEWS) 2 Standardising the assessment of acute-illness severity in the NHS. Updated report of a working party. London: 2017.
2. Ede J, Jeffs E, Vollam S, Watkinson P. A qualitative exploration of escalation of care in the acute ward setting. Nursing in Critical Care. 2020;25:171–178.
3. Louch G, Albutt A, Harlow-Trigg J, Moore S, Smyth K, Ramsey L, O’Hara JK. Exploring patient safety outcomes for people with learning disabilities in acute hospital settings: a scoping review. BMJ Open 2021;11:47102.
Creating an easy to construct, low-cost aspiration simulator for airway training
Authors: Warburton Sean , Hartopp Andrew 
Published: November 2022

Aspiration of gastric contents remains the commonest cause of death during anaesthesia, accounting for 50% of deaths and occurring more frequently than cannot intubate, cannot oxygenate (CICO) events [1]. Despite this, training for CICO is ubiquitous while rehearsal of aspiration management is rare. Soiled airway simulation has been shown to reduce the time to intubation with less volume entering the lungs, a factor known to correlate with the severity of aspiration [2]. Initially developed by Dr DuCanto, high-fidelity vomit simulators have existed since 2014 however cost (£1,595) precludes their widespread use. Low-cost models have since been described, however, the materials are sourced from hardware stores, relatively expensive, require skills to construct, utilise noisy pumps, and some even require electrical safety considerations [3]. We aimed to improve access to aspiration training by designing an aspiration simulator that is easy to construct and low-cost.
Employing an iterative design process we created an aspiration simulator using materials readily available in the operating theatre. The final model requires an intubatable manikin with an oesophagus, such as the Laerdal Airway Management Trainer
The setup silently produces a titratable flow of up to 250 ml per minute, sufficient to flood the oropharynx within 30 seconds. The simulation itself can be set up in under 10 minutes, used several times before requiring refilling, and is easily transported between theatres as a part-task trainer or concealed for a multi-disciplinary simulation (Figure 1, bottom left). All parts are reusable and the total cost equals £9.90 (excluding the manikin, which is undamaged). Our simulator was tested on a cohort of 16 middle-grade anaesthetic trainees and its performance was evaluated using pre and post-course questionnaires (scale 0–10). All successfully intubated the simulator. Average user-rating scores for realism were 8.4/10 while confidence in managing soiled airways improved from 6.2/10 to 8.9/10 after exposure to the simulation.
Soiled airway simulation can be simple and affordable, creating a realistic environment to practise the unique skills necessary to manage this important yet under-rehearsed cause of death during anaesthesia.
1. Cook T, Woodall N, Frerk C. Major complications of airway management in the UK: results of the Fourth National Audit Project of the Royal College of Anaesthetists and the Difficult Airway Society. Part 1: Anaesthesia †. British Journal of Anaesthesia. 2011;106(5):617–631
2. Jensen M, Louka A, Barmaan B. Effect of Suction Assisted Laryngoscopy Airway Decontamination (SALAD) Training on Intubation Quality Metrics. Air Medical Journal. 2019;38(5):325.
3. Sampson C, Pauly J, Horner J. Low-cost Portable Suction-Assisted Laryngoscopy Airway Decontamination (SALAD) Simulator for Dynamic Emesis. Journal of Education and Teaching in Emergency Medicine. 2019;4(2).
Detection of Remdesivir by Liquid Chromatography with Tandem Mass Spectrometry in a Patient with SARS-CoV-2 Infection
Authors: Petrus Jakub , Grondžák Tomáš , Čepová Jana , Dunovská Kateřina , Hosnedlová Božena , Beroušek Jan , Průša Richard , Kizek René , Klapková Eva 
Published: November 2022

One of the officially approved medications for the treatment of the pandemic disease COVID-19, caused by the SARS-CoV-2 virus, is remdesivir. This antiviral molecule is a prodrug that is metabolized into its active form (an ATP analogue). Because of its hepatotoxicity and nephrotoxicity, it is necessary to monitor the serum concentrations of remdesivir. For the therapeutic drug monitoring of remdesivir, a method using liquid chromatography with tandem mass spectrometry (LC-MS/MS) in positive electrospray ionization mode was developed. Mass detection was done via triple quadrupole in the Multiple reaction monitoring mode. Separation was done on Zorbax C18 column at 35 °C in mobile phase gradient and flow 0.4 mL min–1 (A – 0.1% formic acid in water, B – 0.1% formic acid in 95% acetonitrile). Time of analysis was 4 minutes. LC-MS/MS method was successfully validated. Calibration was done in blood serum and plasma and it was linear in the range of tested concentrations (0–1000 ng mL–1). Samples were prepared by protein precipitation. The method was used to measure remdesivir concentration in a patient with SARS-CoV-2 infection. The measured concentration 60 minutes after remdesivir application was 175±15 ng mL–1.
Al interior de la violencia: animar la memoria a través de la Bestia
Authors: Jairala Ignacio 
Published: November 2022

Bestia (Chile, 2021)
Año: 2021
Duración: 15’ 54”
Director: Hugo Covarrubias
Guion: Martín Erazo y Hugo Covarrubias
Producción Ejecutiva: Tevo Diaz
Distribución: Miyu Distribution
Dirección de Fotografía: Hugo Covarrubias
Dirección de Sonido: Roberto Espinoza
Música Original: Ángela Acuña y Camilo Salinas
A Study to Identify the Reasons for Farmers Inclination Towards Organic Farming: An Empirical Study
Authors: Pallathadka Laxmi Kirana , Pallathadka Harikumar , Manoharmayum Dolpriya Devi 
Published: November 2022

Food quality and wellbeing are the two significant variables that have steadily expanded consideration among everyday purchasers. Because of the presence of higher pesticide buildup, more nitrate, significant metals, chemicals, anti-infection buildup, and hereditarily altered life forms, expectedly grown food variations have huge antagonistic wellbeing repercussions. Besides, ordinarily developed food sources are less nutritious and contain lesser measures of defensive cell reinforcements. In the mission for more fast food, the interest in naturally developed food varieties has expanded over a long time because of their potential medical advantages and food handling concerns. Natural food creation is characterized as development without using substance manures and manufactured pesticides or hereditarily altered life forms, development chemicals, and anti-infection agents. The prevalence of naturally developed food sources is expanding step by step, inferable from their nourishing and medical advantages. Natural cultivating likewise secures the climate and financially affects a country. India is a country that is given native abilities and the possibility for development in natural farming. Even though India was a long way behind in the reception of natural cultivating for a few reasons, by and by, it has accomplished fast development in natural agribusiness. It has presently become one of the biggest natural makers on the planet. Subsequently, natural cultivating significantly affects the strength of a country like India by guaranteeing a good turn of events.
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI KELUHAN MUSCULOSKELETAL DISORDER PADA PEKERJA LAUNDRY
Authors: Asnel Roza , Pratiwi Anggi 
Published: November 2022

Musculoskeletal Disorders (MSDs) adalah sekelompok kondisi patologis yang mempengaruhi fungsi normal dari jaringan halus system. Berdasarkan survey awal yang dilakukan kepada 5 pekerja laundry dari Kecamatan Tampan terdapat 4 (80%) pekerja memiliki gejala seperti Musculoskeletal Disorder. Tujuan penelitian ini adalah untuk mengetahui hubungan umur, indeks massa tubuh, beban kerja, masa kerja dengan keluhan Musculoskeletal. Penelitian ini adalah penelitian kuntitatif dengan desain cross sectional. Populasi yang digunakan dalam penelitian yaitu 46 tempat laundry dengan 70 jumlah pekerja berjenis kelamin perempuan di Kecamatan Tampan. Seluruh populasi dijadikan responden. Alat ukur penelitian adalah kuesioner. Analisis univariat dan bivariat menggunakan uji chi square. Hasil penelitian menunjukkan hubungan kategori umur (P value = 0,000134), indeks masa tubuh (P value = 0,006), beban kerja (P value = 0,305), masa kerja (P value = 0,000183). Kesimpulan dari penelitian ini adalah adanya hubungan antara umur, indeks masa tubuh, masa kerja dengan keluhan Musculoskeletal dan tidak adanya hubungan antara beban kerja dengan keluhan Musculoskeletal. Disarankan kepada pemilik laundry bisa menerapkan cara kerja yang ergonomis, menggunakan alat bantu untuk mengurangi beban kerja, dan membatasi masa kerja karyawan tidak lebih dari tiga tahun.
HUBUNGAN AKTIVITAS BERULANG, SIKAP KERJA DAN LAMA KERJA DENGAN KELUHAN KELELAHAN OTOT PEKERJA GETAH KARET
Authors: Entianopa Entianopa , Harahap Putri Sahara , Rahma Devita 
Published: November 2022

Kelelahan otot merupakan fenomena berkurangnya kinerja otot setelah terjadi tekanan melalui fisik untuk suatu waktu disebut kelelahan otot secara fisiologis, yang ditunjukkan tidak hanya dengan berkurangnya tekanan fisik tetapi juga makin rendahnya gerakan.Tujuan dari penelitian ini adalah untuk mengetahui hubungan dari aktivitas berulang, sikap kerja, lama kerja dengan kelelahan ototpada pekerja petani getah karet di Desa Suka Jaya kecamatan Bayung Lencir sumatera selatan tahun 2018. Penelitian ini merupakan penelitian analitik dengan pendekatan cross sectional. Sampel pada penelitian ini dia ambil dengan menggunakan teknik pengambilan sampel secara sampling insidental yaitu seluruh pekerja penyadap getah karet. Data dianalisis secara univariat dan bivariat dengan menggunakan uji Chi Square.Hasil penelitian menunjukan bawha responen rendah sebanyak 10 (13,69%), responen sedang sebanyak 44 (60,27%), responen tinggi sebanyak 19 (26,02%) mengalami kelelahan otot. Adapun hasil uji statistik menunjukan bahwa variabel aktivitas berulang (P=0,72), sikap kerja (P=0,42) tidak terdapat hubungan yang singnifikan dengan kelelahan otot, lama kerja (P= 0,01) terdapat hubungan yang singnifikan dengan kelelahan otot.
Health in digital environment
Authors: Safonicheva Olga G. , Ovchinnikova Marina A. , Kachenkova Ekaterina S. 
Published: November 2022

Office work is associated with movement restrictions, muscle stress, burnout and other risk factors that negatively affect the health of working - age people. The coronavirus epidemic has changed the labor market: neither employers nor employees were prepared to tackle the challenges of moving to remote work. Therefore, search for solutions to preserve health of remote workers in the context of self-isolation and digital transformation is a priority medical and social task. Pilot research for examination of the office-workers state included interviews, psychological, neurological tests and methods of instrumental visualization. The aim of the study was to identify the signs of the emotional impact of remote work and develop exercises to prevent physical inactivity, as well as technologies for monitoring of individuals’ health. The survey revealed that 80% of office workers have stress and burnout in an epidemic situation, as well as a loss of interest in work and professional achievements. Burnout was accompanied with increased irritability, sleep disorders. Neurological examination revealed muscle spasms and “tunnel” neurovascular disorders in the cervical spine and postural displacement in all persons. Electrophysiological research indicated cerebral acidosis and brain hypoxia in 50% of examined individuals. The programs for postural correction and cerebral metabolism included special coordination and breathing exercises. Recommendations to healthy lifestyle and workplace reorganization were given to all persons. Digital transformation is a challenge that requires changes in legal, organizational, psychological and infrastructural approaches to preserve the health of remote workers in the new environment.
PEMBUATAN LILIN AROMATERAPI DENGAN PENAMBAHAN MINYAK JERUK MANIS DI DUSUN SERI, DESA URIMESSING, KOTA AMBON
Authors: Grace Sipahelut Sophia , Mailoa Meitycorfrida , C. D. Tuhumury Helen 
Published: November 2022

Tujuan utama dari kegiatan pengabdian ini adalah untuk meningkatkan pengetahuan dan keterampilan masyarakat dalam membuat lilin aromaterapi dengan penambahan minyak atsiri jeruk manis di Dusun Seri, Desa Urimessing, Kecamatan Nusaniwe, Kota Ambon. Sasaran kegiatan ini adalah masyarakat Dusun Seri, Desa Urimessing, sedangkan metode yang digunakan adalah penyuluhan, pelatihan/praktek dan evaluasi. Berdasarkan hasil pengamatan dan kuesioner, terjadi peningkatan pengetahuan masyarakat mengenai khasiat lilin aromaterapi, manfaat minyak atsiri, dan teknik pembuatan lilin aromaterapi berbasis minyak atsiri. Masyarakat mendapat informasi baru tentamg pemanfaatan lilin aromaterapi sebagai media relaksasi yang mudah dan murah. Di samping itu, masyarakat memiliki keterampilan baru dalam membuat lilin aromaterapi berbahan aroma minyak atsiri jeruk manis. Melalui kegiatan ini juga dapat meningkatkan kesehatan masyarakat karena dengan menghirup aroma dari lilin aromaterapi akan membuat pikiran menjadi tenang dan mengurangi kecemasan. Kegiatan pengabdian ini mampu memotivasi peserta membuat lilin aromaterapi untuk digunakan bersama keluarga. Peserta sangat antusias mengikuti kegiatan ini dari awal sampai akhir
Research on Sustainable Development Model of Scenic Spots under Carbon Neutrality——Take Yashan in Dayu County as a Cace
Authors: Liu Chuanxi , Liu Hongxia 
Published: November 2022

Carbon neutrality has put forward new requirements for the low-carbon development of tourism. The construction of carbon neutral scenic spots is an important content to promote the tourism industry to achieve the goal of carbon neutrality. Taking Yashan scenic spot in Dayu County, Jiangxi Province as a cace, this paper analyzes the "two-way, three-dimensional and stereoscopic" carbon neutral sustainable model and characteristics of Yashan scenic spot. This model achieves the maximum carbon sequestration through the construction of the whole forest scenic spot, forms the three-dimensionall collaborative support of "mechanism system + Intelligent system + environmental education", and constructs a multi-dimensiona carbon reduction behavior system composed of low-carbon transportation, energy conservation, renewable energy, resource recycling, low-carbon creative products and other measures, which directly promotes the implementation of the carbon neutralization goal of the scenic spot.
Informasjonssamtalen med barn som pårørende ved selvmordsatferd – en selvfølgelig del av selvmords forebyggingsarbeidet?
Authors: Moe Kristin Frisch , Moen Grete L. , Wiig Synøve M. 
Published: November 2022

Ivaretakelse av barn som er pårørende ved selvmordsatferd, kan være god forebygging. Oppsummert forskning indikerer statistisk risiko for generasjonsoverføring av selvmordsatferd mellom foreldre og barn. Konkret informasjon fra trygge voksne kan bidra til å forebygge feiltolkning og skyld, og hjelpe barnet til å skape en sammenheng i det som har skjedd. Helsepersonell har lovmessig plikt til å ivareta barn som pårørende, men kvier seg for å gjennomføre informasjonssamtaler når det er selvmordstematikk.
Det er utarbeidet veiledere for barn som etterlatte og barn som pårørende ved ulike psykiske helseproblemer, men ikke der barnet er pårørende ved selvmordsatferd. Vår erfaring er at det er et kunnskapshull når det gjelder tematikken. Dette er en stor utfordring fordi selvmordsatferd i familien er skamfullt for mange og snakkes lite om.
Målet med denne artikkelen er å peke på noen av de viktigste utfordringene og mulighetene vi som helsepersonell står overfor ved gjennomføring av informasjonssamtalen ved selvmordsatferd. Vi belyser dette gjennom beskrivelse av todagerskurset «Ivaretakelse av barn som pårørende når mor eller far strever med selvmordsatferd» og en veiledningsprosess ved et akutteam. Kurset og veiledningen viser hvordan kunnskapen kan implementeres.
Snow leopard - human conflict as a conservation challenge - a review
Authors: Moheb Zalmai , Fuller Todd K. , Zahler Peter I. 
Published: November 2022

Human conflict with large carnivores continues to be a great conservation challenge, and conflict with snow leopards (Panthera uncia) has been studied to understand causes and propose mitigation schemes. While the nature of snow leopard-human conflict is similar in most cases, reported studies have been case- and area-specific with mitigation strategies not necessarily based on a synthesis of relevant literature. We reviewed snow leopard literature published from 1970-2020 to identify the main drivers of human-snow leopard conflict (HSLC) and describe conservation and conflict mitigation strategies commonly employed. Based on 47 relevant peer-reviewed articles, review papers, book chapters, project reports, and other grey literature, we identified four major conflict domains: livestock management-related, socio-economic/human-related, ecological, and policy-related. Most articles suggested more than one conflict mitigation scheme. Three conflict mitigation domains – preventive, supportive, and compensatory – were widely reflected in the snow leopard-human conflict literature. The most commonly reported mitigation schemes included: 1) building or predator-proofing corrals; 2) training shepherds and improving livestock guarding; 3) livestock insurance schemes; 4) compensation for livestock predation; 5) capacity building, education, and awareness programs; and 6) improved breeding and use of guard dogs. Future management efforts need to tailor their approach depending on cultural, economic, and ecological circumstances.
ANALYSIS OF AIR-BORNE POLLUTANTS DURING SECOND WAVE OF COVID-19 PANDEMIC OVER MAJOR CITIES OF INDIA
Authors: KUMAR ADARSH 
Published: November 2022

In this paper, we analyzed air-borne pollutants like PM2.5, PM10, NO2, SO2, CO and Ozone obtained from twelve air-quality monitoring stations operated by various central and state-pollution control agencies in different parts of India during second wave (March to May’ 2021) of Covid-19 pandemic. Our results show positive correlations between Covid-19 cases and PM2.5/10 over Delhi (+0.049) and Lucknow (+0.097) of Northern India. Lowest PM2.5 concentrations was observed over Chennai (~19), which was due to lockdown restrictions imposed by Tamilnadu state government. Pearson coefficients of PM2.5, PM10 and NO2 were observed to be negative for all the three chosen major cities of Southern India, and thereby, indicating that corona pandemic was not affected by air-borne particulates over Southern India. The average PM10 density of Eastern India was estimated to be maximum at Varanasi (~161) and lowest at Kolkatta (~85), however Pearson coefficient, P was fond to be negative for Kolkatta (-0.72). Further, over Western India, pearson coefficients of PM2.5, PM10, NO2, SO2 and CO were estimated to be negative for all the three chosen major cities. Ozone was found to have its positive trends at Ahmedabad (+0.32) and negative trends for both Jaipur (-0.044) and Mumbai (-0.017). Student t-test was also applied to test the significance between two independent data sets.
BIOCHEMICAL CHARACTERIZATION OF BORAGE (Borago Officinalis L)
Authors: SELMI ABIR , MOUHBI RABIAA , DALLALI SANA 
Published: November 2022

Borage (Borago officinalis) is an annual herb which is cultivated for medicinal and culinary uses. The present work details the biochemical characterization of borage. We tested the antioxidant activity in-vitro, using the DPPH test. Our results, also, showed that the different parts analysed contain very high levels of total polyphenols. Indeed, the leaves are characterized by the highest concentration (3.42±0.24 mg EAG/g MS), followed by the flowers (2.65±0.28 mg EAG/g MS) and the stems (2.25±0.03 mg EAG/g MS). In addition, the total flavonoid contents of Borago Officinalis L. vary significantly depending on the organ studied. The stems are characterized by the highest concentrations (437.87±32.14 mg Eq Q/g MS), whereas the flowers represent the lowest concentrations (333.33±38.56 mg Eq Q/g MS). The analyses of Total tannin have shown that the highest contents (592.53± 46.18 mg EqAT/g MS) are observed in the stems, while the leaves and flowers had similar concentations. (413.68±21.99 mg EqAT/g MS, for flowers; 454.12±17.59 mg EqAT/g MS for leaves). Analyses of condensed tannins have shown that the aqueous extract of the Borago Officinalis L. stem, is cacerized by the highest rates (99. 54±0.64 mg EqCAT/g MS), the leaves and the flowers have average rates (53.63±3.85 mg EqCAT/g MS and 82.27±5.78 mg EqCAT/g MS, respectively). Antioxidant activity was evaluated by the DPPH test. In the three extracts studied, it was observed that the percentage of inhibition (IC50) of the DPPH radical increases as function of the concentration and that the three extracts have a high antioxidant capacity. This is reflected in low IC50 values, which oscillated between (104.78±2.54 µg/ml), and (125.45±3.97 µg/ml), in aqueous extract of stem and of flowers, respectively. However, the anti-radical, of various extracts, remains lower, compared to that of ascorbic acid (IC50=73.15±5.12µg/ml), Used as a reference molecule.