bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENINGKATAN HASIL PANEN DAN KUALITAS HIDUP PETANI KOPI DENGAN POLA PEMBERDAYAAN (STUDI KASUS DI DESA REMPEK, KABUPATEN LOMBOK UTARA)
Authors: Bagus Singandaru Adhitya , Mansur Afifi  , Muhammad Alwi  , Baiq Ismiwati  
Published: September 2022

Penelitian ini dilakukan di Desa Rempek, Kabupaten Lombok Utara. Adapun tujuan penelitian ini adalah untuk menganalisis dampak dari model pemberdayaan petani kopi yang dilakukan pengusaha dalam memproduksi ‘Green Bean’ yang berkualitas terhadap pendapatan dan kualitas hidup mereka. Selain itu, penelitian ini bertujuan merekonstruksi model pemberdayaan dan kolaborasi antara pengusaha dan petani kopi agar produksi dapat ditingkatan sehingga kualitas hidup mereka semakin membaik.
Metode yang digunakan dalam penelitian ini adalah metode Kualitatif dengan pendekatan Studi Kasus. Informan dalam penelitian ini terdiri dari petani kopi, pengusaha, dan pihak-pihak yang terlibat dalam kegiatan kerjasama tersebut. Adapun untuk mendapatkan informasi, peneliti menggunakan metode wawancara.
Hasil penelitian menunjukkan, pemberdayaan dan pendampingan yang mengarah ke sistem direct trade yang dilakukan oleh pengusaha, telah mampu memberikan perubahan pendapatan bagi para petani kopi di wilayah tersebut. Pemberdayaan dan pendampingan yang bersifat menyeluruh dan kontinyu tersebut ternyata tidak hanya menyasar para petani kopi saja, tetapi juga melibatkan tim pengolah yang terdiri dari Ibu-ibu di wilayah tersebut. Alhasil, tim pengolah juga mampu memproduksi bubuk kopi berkualitas hingga mampu menembus pasar Kalimantan dan Sulawesi.
UJI EFEKTIVITAS EKSTRAK BIJI PALA (Myristica fragrans Hout) SEBAGAI ANTIBAKTERI TERHADAP PERTUMBUHAN Vibrio parahaemolyticus PENYEBAB PENYAKIT VIBRIOSIS PADA IKAN KERAPU (Epinephelus spp.) IN VITRO
Authors: Khairiyah Rizky Aldi Zulfaizi , Setiabudi Gede Iwan , Mastuti Indah , Mahardika Ketut 
Published: September 2022

Salah satu ikan yang paling unggul untuk dibudidayakan di Indonesia ialah kerapu. Akan tetapi komoditas ini sering dihadapkan oleh kematian masal yang di akibatkan oleh penyakit vibriosis seperti bakteri V. parahaemolyticus. Telah banyak pemakaian antibakterial yang berasal dari bahan alami yang terus dilakukan pengembangan. Biji pala (Myristica fragrans Hout) ialah tanaman yang masih tradisional dengan kandungan zat antibakterialnya yang banyak. Dilaksanakannya pengujian ini yakni guna mengetahui efektivitas dari ekstrak biji pala (Myristica fragrans Hout) sebagai antibakteri terhadap pertumbuhan V. parahaemolyticus secara in vitro. Metode penelitian menggunakan metode eksperimen dengan rangcangan acak lengkap non faktorial. Biji pala dilakukan proses ekstraksi dengan pemakaian etanol 96% dan pemanasan rendah dengan metode maserasi. Uji efektivitas ekstrak biji pala pada konsentrasi 5%, 10%, 20% dan 40% terhadap V. parahaemolyticus dengan metode yang digunakan yakni cakram disk. Erythromycin sebagai kontrol positif dan aquades sebagai kontrol negatif. Hasil penelitian menunjukan bahwasanya ekstrak biji pala konsentrasi 40% memiliki zona hambat terhadap V. parahaemolyticus paling tinggi yaitu, 10,8±0,57 mm (P<0,05) dibandingkan dengan ekstrak biji pala pada konsentrasi 5-20% (7,3±0,84, 9,0±0,50, 9,8±0,76 mm). Zona hambat ekstrak biji pala tersebut masih lebih rendah (P<0,05) dibandingkan dengan zona hambat dari erythromycin yaitu 19,5±0,5 mm. Namun demikian, ekstrak biji pala memiliki potensi menghambat pertumbuhan V. parahaemolyticus.
Management of Post-COVID-19- Related Olfactory Dysfunction
Authors: Castro Gomes Ana Catarina , Soutinho Joana , Pereira Ana Luísa 
Published: September 2022

Evidence suggests that the prevalence of olfactory dysfunction (OD) occurs in 50% of patients with COVID-19.Emerging data suggest a high rate of early and spontaneous recovery, but approximately 10% of patients showed no improvement at 4-6 weeks after recovery. Given the high prevalence of COVID-19, a considerable number of patients will experience this morbidity.Thus, the main goal of this review is to define a guideline protocol for patients recovered from COVID-19, who present with olfactory dysfunction. In those cases, it is important to start by classifying the severity of this change and rule out other possible underlying etiologies, which may require further investigation.The treatment with best results is olfactory training. Additionally, the use of nasal corticosteroid spray or omega-3 supplementation may be recommended.It should be noted that those conclusions are based upon clinical trials whose patients were infected by viruses other than SARS-CoV-2. This way, further study and validation regarding the treatment of this condition should be carried out as the pandemic progresses.
Colecistite Aguda Alitiásica: A Propósito de uma Causa Inusitada
Authors: Guimarães Maria João , Carvalho Ana Cristina , Gonçalves Sameira Manuela , Dinis João Manuel 
Published: September 2022

A colecistite aguda alitiásica é uma doença inflamatória aguda da vesícula biliar, sem evidência de cálculos e com patogénese multifatorial. Observa-se sobretudo em pacientes com múltiplas comorbilidades ou estados de imunossupressão, encontrando-se associada a maior morbilidade e mortalidade, comparativamente com a entidade litiásica.Doente, género feminino, 50 anos de idade, com infeção recente por SARS-CoV-2 recorreu a teleconsulta por epigastralgia com irradiação dorsal, com quatro dias de evolução, associado a náuseas, com melhoria sintomática naquele dia. Solicitados estudo analítico, ecografia abdominal e endoscopia digestiva alta urgentes.A ecografia demonstrou “colecistite aguda alitiásica”. Referenciada ao serviço de urgência com consequente colecistectomia por laparotomia, após conversão de laparoscopia, revelando perfuração pilórica por espinha de peixe com inflamação vesicular por contiguidade.A colecistite aguda alitiásica representa 2% a 15% dos casos de colecistite aguda, ocorrendo sobretudo acima dos 60 anos e no género masculino. A doente em causa não apresentava o biótipo, as comorbilidades e a apresentação clínica típicos desta patologia. A infeção recente por SARS-CoV-2 levantou a suspeita de um papel etiológico, contraposto após a cirurgia. A ingestão de corpos estranhos é considerada comum, mas apresenta maioritariamente um curso benigno, com complicações em menos de 1% dos casos. A doente apresentava escassos fatores predisponentes à ingestão de corpos estranhos. Uma tomografia computorizada no período pré-cirúrgico poderia ter esclarecido a etiologia e contribuído para a orientação do procedimento.Eis um caso clínico de uma patologia invulgar, de etiologia rara, numa doente atípica, com um desfecho bem-sucedido, em plena pandemia COVID-19.
Qual a Função da Igreja Frente à Revelação?
Authors: Lepargneur Hubert 
Published: September 2022

Qual é o sentido da palavra Revelação de que pretendemos falar?
1) Seria oportuno lembrar, de início, que a Palavra de Deus não se identifica com a letra da Escritura: a Palavra de Deus é ativada pelo Espírito Santo que atualiza seu sentido no leitor de hoje (Rahner, Benoit, Grelot, Schillebeeckx). «Nunca se deve separar a Palavra de Deus como intervenção de Deus da atividade significante do Povo de Deus. Neste sentido, podemos dizer que a Revelação é sempre uma hermenêutica, e portanto uma tradição» (Geffré). Consequentemente a Revelação é mais do que a comunicação ou leitura material da letra da Bíblia...
O marcador EM na elaboração das representações temporais
Authors: Rocha Elizabeth 
Published: September 2022

A preposição EM é invariavelmente ligada ao valor de tempo. Encontramo-lo em todas as classificações das gramáticas tradicionais. Todavia, os trabalhos classificatórios que versam sobre a preposição enquanto introdutor de complementos temporais parecem ser insuficientes para dar conta das múltiplas flutuações cotextuais, bem como da identidade semântica do marcador em foco. Neste trabalho, considerando-se o domínio semântico da construção do tempo na enunciação linguística, visamos a descrever a variação cotextual da preposição EM, quer dizer, precisar quais as representações temporais implicadas nos diversos cenários enunciativos aos quais esse marcador se integra, e, para, além disso, propor uma hipótese de sua invariância de sentido, quer dizer, determinar os princípios organizadores que presidem a elaboração de tais representações.
Experience in the Treatment of Wounds of Circulatory Organs in the Chest and Main Vessels of Other Localizations in Wartime
Authors: Hrabovskyy Nazar Z. 
Published: September 2022

The article presents the principles of providing care for injuries to the heart, aorta, pulmonary artery, or other main vessels. The described principles can be applied in the treatment of civil injuries.
The aim. Consider a treatment tactic in the cases of heart and main vessels combat injuries using own experience.
Materials and methods. Twelve cases of combat wounds of blood circulation organs in the chest were analyzed: 5 gunshot injuries of the subclavian vessels, 4 gunshot injuries of the heart, 1 gunshot injury of the ascending aorta, 1 gunshot injury of the pulmonary artery and 1 suspected gunshot injury of the left ventricle.
Also we analyzed 78 cases of combat gunshot injuries of main vessels of other locations: 3 injuries of vessels of the neck, 68 injuries of main vessels of limbs, 6 injuries of iliac arteries, 1 injury of abdominal aorta.
Most of the operations, with the exception of those that required artificial blood circulation, were performed in advanced hospitals at the II level of military medical evacuation, which enabled to shorten the time from injury to the performance of the final surgical intervention and save life or limbs.
Results and discussion. Two cases with penetrating wounds to the chest and damage to the subclavian vessels were fatal. Death was attributed to uncontrolled chest bleeding.
Among the 78 cases of injury of main vessels of other locations, one case with damage to the iliac arteries was fatal, and death also occurred as a result of uncontrolled massive intra-abdominal bleeding.
Conclusions. Wounded individuals with unstable hemodynamics against the background of ongoing massive bleeding and with suspicion of injury of the heart or main vessels in the chest should be operated on immediately. Due to the urgency of performing such operations and impossibility of an adequate additional examination, localization and degree of the damage to the organs of the circulatory system is determined during the operation. A thoracoscopic approach can be used in stable patients with non-penetrating gunshot wounds to the heart.
In the relatively stable condition of patients with an established injury of the heart, aorta, or pulmonary artery, it is advisable to perform additional examinations. Patients with trauma to the main vessels of the extremities and ischemia thereof need rapid revascularization.
Experience of Endovascular Treatment of Pulmonary Artery Atresia
Authors: Imanov Elnur , Ditkivskyy Igor O. , Plyska Oleksandr I. , Mazur Oleksandra A. , Sloboda Artemiia O. 
Published: September 2022

The aim. To analyze the results of the use of endovascular treatments for pulmonary artery atresia (PAA).
Materials and methods. Treatment of this heart defect at the National Amosov Institute of Cardiovascular Surgery of the NAMS of Ukraine with application of endovascular methods began in 2006. Since then, 138 patients were operated, 57 of them female (41.3%) and 81 (58.6%) were male. Endovascular methods were used in 23 patients, and 115 patients underwent open-heart surgery. The mean length of hospital stay was 25±16.3 days.
Of 115 patients who underwent open-heart surgery, 62 (54%) were male and 53 (46%) were female. On the day of surgery, the mean age of these patients was 607.8±1023.7 days, mean weight was 8.8±8.1 kg. The average length of hospital stay was 26±18.6 (maximum 215, minimum 5). Of 23 patients who underwent endovascular surgery, 18 (77%) were male and 5 (23%) were female. The mean age on the day of surgery was 220.5±650.2 days, mean weight was 5.0±4.4 kg. The mean length of hospital stay was 22±5.7 days (maximum 34, minimum 4).
In the treatment of PAA, a stepwise procedure is used, correcting part of the defect at each stage and thereby reducing the traumaticity of the operation. In our case, correction of the defect was performed on the open heart and using endovascular methods of treatment. After endovascular interventions, no fatal effects were observed. Open-heart surgery was performed in case if endovascular interventions could not be performed. The condition of such patients was usually more severe. It should also be noted that the open-heart surgery itself is a serious trauma to the body. Due to the above, postoperative period in this group of patients more often proceeded with complications. Due to more severe preoperative condition of the patients and surgical trauma, in some cases of open-heart interventions, some patients did not recover after surgery. As a result, the total mortality in the group of patients who underwent open-heart surgery was 13.0%. In addition, in 7 cases, such surgery was supplemented by the Rashkind procedure. In case of recurrent surgery after 6 months, stenting of patent ductus arteriosus was performed. Repeated surgical interventions were accompanied by the improvement of the condition and the patients were discharged from the clinic in satisfactory condition.
Conclusions. PAA is one of the most complex congenital pathologies of the heart and main vessels, and therefore preservation of such a newborn depends on the preservation of patent ductus arteriosus. Endovascular surgery for PAA is the operation of choice that allows to prepare the patient for the next stage of treatment, including open-heart surgery. Endovascular interventions in PAA are minimally invasive, which increases the chances of patients with complicated anatomy to survive despite their serious condition on admission to the hospital.
The role of highly toxigenic CagA and VacA strains of Helicobacter pylori in gastric carcinogenesis. Review
Authors: Nikulina L. M. , Solovyova G. A. 
Published: September 2022

Gastric cancer takes the 4th place as the main cause of death among oncological diseases in the world. The risk factors of gastric cancer include genetic predisposition, alcohol abuse, smoking, low socio‑economic level, nutritional characteristics, Epstein–Barr virus and Helicobacter pylori infection. Helicobacter pylori bacterium is the only statistically proven risk factor for stomach cancer. Gastric cancer develops in less than 3 % of ­H. pylori ‑infected patients, suggesting a unique interaction between the host immune response and H. pylori virulence factors. Expression of oncogenic cytotoxin‑associated protein gene A (CagA), vacuolating cytotoxin A (VacA), and outer membrane proteins is important for H. pylori in host pathogenesis. The paper gives consideration for the relationship between the virulence factors of H. pylori and the host, which is necessary for a better understanding of the pathogenesis and prevention of carcinogenesis. The strategy for the prevention of gastric cancer includes eradication therapy, but it is complicated by the growth of resistance to antimicrobial drugs. Only insignificant number of papers investigate effects of pathogenicity factors of H. pylori (CagA+ and VacA+) on the development of atrophy, intestinal metaplasia and dysplasia. In the literature, there is little data on the difference in antibiotic resistance between H. pylori highly toxigenic and non‑toxigenic strains.
The aim of the article is to present current data on the impact of highly toxigenic CagA+VacA+ strains of H. pylori on the processes of gastric carcinogenesis and to determine their role in resistance to clarithromycin. Investigation of the relationship between highly toxigenic CagA and VacA strains with clinical and morphological manifestations of gastritis and antibiotic resistance will enable preventing the progression of precancerous changes and using effective treatment tactics.
Solitary pulmonary nodules: etiology, sizes and topographical features
Authors: Kuzovkova S.D. , Liskina I.V. , Zagaba L.M. , Melnik O.O. 
Published: September 2022

Objective — determination of the size and localization of solitary pulmonary nodules (SPN) of various etiology and their qualitative-quantitative characteristics when separated into malignant and benign formations.
Materials and methods. The randomized retrospective study involved 422 patients who were hospitalized in the National Institute of phthisiology and pulmonology named after F.G. Yanovsky from 2017 to 2021. Criteria for inclusion in the study group are focal lesions of the lungs of unclear etiology, the size of which did not exceed 3,0 cm, and the presence of no more than 3 foci in both lungs of one patient according to X-ray examination. The number, size and location of the SPN were determined according to X-ray examination or computed tomography of the chest organs.. A total of 473 nodules were found. The etiology of SPN was determined according to the results of histological and cytological examination of biopsy or operative material and/or microbiolo­gical data. All nodules were divided into three groups, depending on their size.
Results and discussion. The etiological spectrum of all revealed SPN in the five-year period is determined. It was established that among all SPN malignant tumors (39.1 %) are dominated the average size of which was (2.14 ± 0.1) cm, on the second place in the number of observations were nodules of infectious origin (31.0 %), the average size — (1.97 ± 0.1) cm, and on the third — benign tumors (18.7 %). the average size — (1.57 ± 0.1) cm. The average size of malignant tumors and SPN of infectious origin was significantly larger than the size of benign tumors and vascular formations. It was shown that in a group with SPN sizes 0.3—1.0 cm malignant tumors amounted to 22.9 %. and in a group with a size from 2.1 to 3.0 cm — 51.5 %, respectively 55.3 % of all SPNs were found in the right lung, 44.7 % in the left. In the upper lobe of the right lung. 52.3 % of nodules were found. which is significantly more than in middle. 16.0 % of SPN (p < 0.001), and the lower lobe — 31.7 % (p < 0.001). In the upper lobe of the left lung. 59.4 % of SPN were diagnosed, and in its lower lobe — 40.6 % (p < 0.001).
Conclusions. Among all solitary pulmonary nodules of various etiology. the largest specific gravity have malignant nodes — 39.1 % and nodules of infectious genesis — 31.0 %. and the average size of these SPN is essentially larger than the size of benign tumors and vascular formations. The percentage of malignancies increases from 22.9 to 51.4 % with an increase sizes of SPN from 1.0 to 3.0 cm. Significant predominance by the number of nodules in size from 1.1 cm to 3 cm is evidence of improper level of detection SPN in Ukraine. Solitary pulmonary nodes are significantly more often found in the right lung. Moreover, lesions of the upper lobes of the right and left lungs are observed more often than the lower lobes of the lungs.
Prevalence of blaIMP-1 among P. aeruginosa isolated from patients with burn infections
Authors: Alghreri Ansam Adnan Ahmed , Alsaadi Kawkab Abdalla , Al-Dahmoshi Hussein O.M. 
Published: September 2022

Carbapenems are often used as antibiotics for treating infections by multidrug-resistant Gram-negative bacteria. Pseudomonas aeruginosa is considered a major cause of health care issues associated with higher mortality and morbidity rates worldwide. This study aimed to detect the prevalence of carbapenemase gene blaIMP-1 that is produced by carbapenem-resistant P. aeruginosa isolated from burn infection patients. A total of 137 burn swabs were collected from burn patients in different hospitals in Babylon province from December 2021 to April 2022. All of the swabs were streaked on selective media cetrimide agar. Antibiotic susceptibility was performed for Imipenem and meropenem and polymerase chain reaction for species specific 16S rDNA gene and blaIMP-1 gene was done for all isolates. 50 isolates were confirmed by amplicon of species-specific 16S rDNA for P. aeruginosa. Results of antibiotic susceptibility for imipenem and meropenem revealed that 5/50 (10%) and 13/50(26%) of P. aeruginosa isolates were resistant to imipenem and meropenem, respectively. Co-susceptibility (co-resistance or co-sensitive) for both imipenem and meropenem results showed 5/50 (10%) display resistance for both imipenem and meropenem, 8/50(16%) display resistance for only meropenem while 37/50(74%) sensitive for both and none was resistant to imipenem and sensitive for meropenem. Phenotypic detection of Metallo-β-lactamase gave inverse result while the Mean±SD of inhibition zone (mm) for imipenem disc (10μg) =29.34±7.11 and for imipenem+EDTA (10 μg+750 μg) =21.8±4.98. Investigation of blaIMP-1 gene revealed that 23/50 (46%) have blaIMP-1 while 18/50 (36%) were sensitive for imipenem and meropenem but have blaIMP-1. The current study concludes the possibility of the presence of resistance gene among phenotypically sensitive isolates pushing great threat of antibiotic misuse and leaving the infection untreated.
El zapallito de tronco: Un cultivo precolombino presente en el Cinturón Hortícola de La Plata (Argentina)
Authors: Martinez Analía 
Published: September 2022

Introducción y Objetivos. El cinturón hortícola de La Plata es una de las regiones productivas más importantes de la provincia de Buenos Aires. Está formado por grandes productores que abastecen a distintas regiones del país, así como también por un núcleo de productores familiares no capitalizados que se dedican a la venta de sus productos en ferias y mercados de la ciudad. Entre sus productos típicos el zapallito de tronco (Cucurbita maxima subsp. maxima var. zapallito) es una hortaliza regional que se destaca por ser muy utilizada para la preparación de diversas comidas. El objetivo de este trabajo es relevar el conocimiento botánico local (CBL) de las familias productoras de La Plata, con el fin de contribuir al mantenimiento de esta variedad que guarda importancia cultural y regional.
Materiales y Métodos. Desde una metodología de tipo etnobótanica se realizaron entrevistas semiestructuradas y observaciones directas a dieciséis informantes claves de la región, quienes caracterizaron experiencias, prácticas e historias del manejo del zapallito en la ciudad.
Resultados. Las familias productoras de zapallito de tronco elijen cultivar esta hortaliza por su rentabilidad, bajo costo y tradición local. Los pequeños productores, en su mayoría de nacionalidad boliviana, han logrado adaptarse a las condiciones ambientales de un escenario distinto para ellos y con los recursos que cuentan aprendieron a responder a los requerimientos hortícolas de la región.
Conclusiones. Es mediante el conjunto de saberes y prácticas que realizan los productores (CBL) que se contribuye a mantener el cultivo del zapallito de tronco en la región.