bluuebunny/crossref_metadata_2025_split huggingface dataset:
Creating equitable access: using OER for socially just educational leaders
Authors: Richardson Sydney , Roebuck Sakho Jacqueline 
Published: October 2022

Purpose
The purpose of this paper is to demonstrate ways in which educator preparation programs can influence educator and administrator support of Open Education Resources (OER). OER is still not used as widely as the researchers would like, even though it was introduced in the year 2002 (Bliss and Smith, 2017). While it is rarely used to a large extent, it is especially lacking in K-12 schools. By introducing OER to educator candidates (including future principals) in their own programs, they may be supportive of OER and invest in them when they work in schools.

Design/methodology/approach
The research was conducted when an OER project was required in educator preparation programs. Two classes totaling 27 students engaged in a group project, creating OER materials and receptacles over the course of the semester.

Findings
Research showed that educator candidates were in favor of using OER thoroughly. Through building their own OER resources, educator candidates understood the importance of creating socially just and equitable learning environments, aligning with diversity, equity, inclusion and belonging.

Originality/value
To the best of the authors’ knowledge, a project like this has not been researched before. This research supports the idea that usage of OER and investment in it should happen for all educator candidates (teachers and administrators).
Audit team equality and audit quality threatening behaviour
Authors: Annelin Alice 
Published: October 2022

Purpose
This paper aims to examine the association between audit quality threatening behaviour (AQTB) and three team equality dimensions: deindividuation, social identity and gender equality. Discrimination among auditors has been experienced in accounting firms across the world, which can lead to behaviour that risks the quality of work. The negative influence of this behaviour can have consequences for clients, audit firms, regulators and the wider society due to the threat on audit quality.

Design/methodology/approach
A questionnaire was conducted at a Big 4 audit firm in Sweden. Members of audit teams that worked together on one specific engagement were asked to give their perceptions of their experience of equality and behaviours within the team. Hypotheses were tested using ordered logistic regression and partial least squares structural equation model.

Findings
Audit teams that experience deindividuation conduct more AQTBs and audit teams with higher social identity conduct less AQTBs. However, the audit team’s social identity can moderate the audit teams’ experience with deindividuation and reduce AQTB.

Originality/value
With a unique data set of practising audit teams, this study is the first to investigate how audit team equality is related to AQTB. Contributions are made to practitioners about audit team dynamics since the AQTB occurs as part of the audit decision-making process that influences audit quality. Inequality also has recruitment and reputation consequences. Thus, contributions are made to the audit market that is interested in audit quality. The study also contributes empirical evidence from an audit team context about behavioural outcomes and the social identity and deindividuation model theory (Klein et al., 2007; Reicher et al., 1995).
Post-traumatic growth from grief – a narrative literature review
Authors: Hurst Robert , Kannangara Chathurika 
Published: October 2022

Purpose
The purpose of this paper is to give an overview of existing literature on post-traumatic growth (PTG), particularly in the ways that it relates to grief.

Design/methodology/approach
This narrative literature review brings together 125 sources and presents them in a readable way.

Findings
There is a great deal of evidence to suggest that PTG can come from grief. This is not always the case, however.

Research limitations/implications
This review presents only a selection of the existing literature – the review is not systematic. However, this allows for a narrative to be crafted, to aid readability.

Practical implications
Suggestions for future research are made throughout, and potential therapeutic applications are mentioned.

Social implications
This paper discusses stigma, in the form of “disenfranchised grief”. In this, social pressures and expectations affect how a person processes their grief psychologically. While movements to increase discourse and reduce stigma are on the rise, more is needed.

Originality/value
This review guides readers through existing literature, providing a wide overview of the topic of PTG in grief.
Transforming e-participation: VR-dialogue – building and evaluating an AI-supported framework for next-gen VR-enabled e-participation research
Authors: Porwol Lukasz , Garcia Pereira Agustin , Dumas Catherine 
Published: October 2022

Purpose
The purpose of this study is to explore whether immersive virtual reality (VR) can complement e-participation and help alleviate some major obstacles that hinder effective communication and collaboration. Immersive virtual reality (VR) can complement e-participation and help alleviate some major obstacles hindering effective communication and collaboration. VR technologies boost discussion participants' sense of presence and immersion; however, studying emerging VR technologies for their applicability to e-participation is challenging because of the lack of affordable and accessible infrastructures. In this paper, the authors present a novel framework for analyzing serious social VR engagements in the context of e-participation.

Design/methodology/approach
The authors propose a novel approach for artificial intelligence (AI)-supported, data-driven analysis of group engagements in immersive VR environments as an enabler for next-gen e-participation research. The authors propose a machine-learning-based VR interactions log analytics infrastructure to identify behavioral patterns. This paper includes features engineering to classify VR collaboration scenarios in four simulated e-participation engagements and a quantitative evaluation of the proposed approach performance.

Findings
The authors link theoretical dimensions of e-participation online interactions with specific user-behavioral patterns in VR engagements. The AI-powered immersive VR analytics infrastructure demonstrated good performance in automatically classifying behavioral scenarios in simulated e-participation engagements and the authors showed novel insights into the importance of specific features to perform this classification. The authors argue that our framework can be extended with more features and can cover additional patterns to enable future e-participation immersive VR research.

Research limitations/implications
This research emphasizes technical means of supporting future e-participation research with a focus on immersive VR technologies as an enabler. This is the very first use-case for using this AI and data-driven infrastructure for real-time analytics in e-participation, and the authors plan to conduct more comprehensive studies using the same infrastructure.

Practical implications
The authors’ platform is ready to be used by researchers around the world. The authors have already received interest from researchers in the USA (Harvard University) and Israel and run collaborative online sessions.

Social implications
The authors enable easy cloud access and simultaneous research session hosting 24/7 anywhere in the world at a very limited cost to e-participation researchers.

Originality/value
To the best of the authors’ knowledge, this is the very first attempt at building a dedicated AI-driven VR analytics infrastructure to study online e-participation engagements.
Microclimatic variation in tropical canopies: A glimpse into the processes of community assembly in epiphytic bryophyte communities
Authors: Shen Ting , Corlett Richard T. , Collart Flavien , Kasprzyk Thibault , Guo Xin‐Lei , Patiño Jairo , Su Yang , Hardy Olivier J. , Ma Wen‐Zhang , Wang Jian , Wei Yu‐Mei , Mouton Lea , Li Yuan , Song Liang , Vanderpoorten Alain 
Published: October 2022

Abstract

Epiphytic communities offer an original framework to disentangle the contributions of environmental filters, biotic interactions and dispersal limitations to community structure at fine spatial scales. We determine here whether variations in light, microclimatic conditions and host tree size affect the variation in species composition and phylogenetic structure of epiphytic bryophyte communities, and hence, assess the contribution of environmental filtering, phylogenetic constraints and competition to community assembly.

A canopy crane giving access to 1.1 ha of tropical rainforest in Yunnan (China) was employed to record hourly light and microclimatic conditions from 54 dataloggers and epiphytic bryophyte communities from 408 plots. Generalized Dissimilarity Modelling was implemented to analyse the relationship between taxonomic and phylogenetic turnover among epiphytic communities, host‐tree characteristics and microclimatic variation.

Within‐tree vertical turnover of bryophyte communities was significantly about 30% higher than horizontal turnover among‐trees. Thus, the sharp vertical variations in microclimatic conditions from tree base to canopy are more important than differences in age, reflecting the likelihood of colonization, area, and habitat conditions between young and old trees, in shaping the composition of epiphytic bryophyte communities.

Our models, to which microclimatic factors contributed most (83–98%), accounted for 33% and 18% of the variation in vertical turnover in mosses and liverworts, respectively. Phylogenetic turnover shifted from significantly negative or non‐significant within communities to significantly positive among communities, and was slightly, but significantly, correlated with microclimatic variation. These patterns highlight the crucial role of microclimates in determining the composition and phylogenetic structure of epiphytic communities.

Synthesis. The mostly non‐significant phylogenetic turnover observed within communities does not support the idea that competition plays an important role in epiphytic bryophytes. Instead, microclimatic variation is the main driver of community composition and phylogenetic structure, evidencing the role of phylogenetic niche conservatism in community assembly.
A More Dynamic Economy
Authors: Leigh Andrew 
Published: October 2022

AbstractEconomic dynamism is fundamental to productivity and living standards. Several important metrics suggest that the Australian economy has become less dynamic over recent decades. The share of workers starting a new job has fallen. Among employing businesses, the start‐up rate has declined. On average, markets have become more concentrated. Mark‐ups have increased. Reinvigorating competition policy may be an important means of boosting dynamism and raising the rate of productivity growth.
Evaluation of suspected drug‐facilitated sexual assault cases in the city of Houston from 2014 to 2020
Authors: Dempsey Sara K. , Rodgers Corissa L. , Stout Peter , Lee Dayong 
Published: October 2022

AbstractDrug‐facilitated sexual assault is a form of sexual violence against an individual incapacitated by alcohol and/or drugs consumed voluntarily or covertly administered. The purpose of this study was to evaluate toxicological results and the associated demographics of sexual assault‐related cases submitted to Houston Forensic Science Center from 2014 to 2020. In total, 1240 samples (1230 cases) were tested during the six‐year period that consisted of blood, urine, or both specimens. Blood was analyzed for ethanol by dual‐column headspace gas chromatography with flame ionization detection. Drug screen analysis was performed preferably on urine specimens using enzyme‐linked immunosorbent assay. Positive screening results were confirmed upon request only due to laboratory policy. A total of 22% (n = 176) of requested samples were confirmed positive. Ethanol was the most prevalent substance detected, present in 17% of the samples (n = 212), followed by 11‐nor‐9‐carboxy‐delta‐9‐tetrahydrocannabinol (THC‐COOH) (n = 118). The combination of ethanol and THC‐COOH was the most frequent one found (n = 17) in cases positive for two or more drugs (n = 101). Demographic data showed the majority of DFSA victims were white (25%) females (72%) with an average age of 27 years old (n = 348). Almost 90% of cases where the presence of drugs was confirmed resulted in no charges being made, either due to lack of suspect information or unknown reasons by the laboratory.
DNA barcoding of Cymbidium by genome skimming: Call for next‐generation nuclear barcodes
Authors: Zhang Le , Huang Yi‐Wei , Huang Jia‐Lin , Ya Ji‐Dong , Zhe Meng‐Qing , Zeng Chun‐Xia , Zhang Zhi‐Rong , Zhang Shi‐Bao , Li De‐Zhu , Li Hong‐Tao , Yang Jun‐Bo 
Published: October 2022

AbstractCymbidium is an orchid genus that has undergone rapid radiation and has high ornamental, economic, ecological and cultural importance, but its classification based on morphology is controversial. The plastid genome (plastome), as an extension of plant standard DNA barcodes, has been widely used as a potential molecular marker for identifying recently diverged species or complicated plant groups. In this study, we newly generated 237 plastomes of 50 species (at least two individuals per species) by genome skimming, covering 71.4% of members of the genus Cymbidium. Sequence‐based analyses (barcoding gaps and automatic barcode gap discovery) and tree‐based analyses (maximum likelihood, Bayesian inference and multirate Poisson tree processes model) were conducted for species identification of Cymbidium. Our work provides a comprehensive DNA barcode reference library for Cymbidium species identification. The results show that compared with standard DNA barcodes (rbcL + matK) as well as the plastid trnH‐psbA, the species identification rate of the plastome increased moderately from 58% to 68%. At the same time, we propose an optimized identification strategy for Cymbidium species. The plastome cannot completely resolve the species identification of Cymbidium, the main reasons being incomplete lineage sorting, artificial cultivation, natural hybridization and chloroplast capture. To further explore the potential use of nuclear data in identifying species, the Skmer method was adopted and the identification rate increased to 72%. It appears that nuclear genome data have a vital role in species identification and are expected to be used as next‐generation nuclear barcodes.
Treatment patterns and outcomes of immunotherapy in extensive‐stage small‐cell lung cancer based on real‐world practice
Authors: Yang Yaning , Ai Xin , Xu Haiyan , Yang Guangjian , Yang Lu , Hao Xuezhi , Yang Ke , Mi Yuling , Wang Guizhen , Zhang Shuyang , Lei Siyu , Wang Yan 
Published: October 2022

AbstractBackgroundThe application of immune checkpoint inhibitors (ICIs) represents a breakthrough in the current landscape for the treatment of extensive‐stage small‐cell lung cancer (ES‐SCLC), but the real‐world outcome is limited. This study aimed to investigate the treatment options and efficacy evaluation of first‐line, second‐line, and subsequent‐line immunotherapy in routine practice.MethodsA retrospective analysis of ES‐SCLC patients treated with ICIs was conducted between May 2016 and September 2021. Objective response rate, disease control rate, progression‐free survival (PFS) and overall survival were assessed between groups to explore the value of ICIs at different treatment time periods. PFS1 and PFS2 were defined as the duration from initial therapy to disease progression or death in first‐line or second‐line treatment.ResultsNinety‐six patients with ES‐SCLC were included. PFS1 was prolonged in patients treated with first‐line ICIs‐combined therapy (median PFS1 7.20 months vs. 5.30 months, hazard ratio [HR] 0.55, 95% confidence interval [CI] 0.36–087, p = 0.0085). For patients who progressed after first‐line ICIs treatment (N = 22), PFS1 + PFS2 was longer in the second‐line ICIs continuation group with no significant difference (median PFS1 + PFS2 11.27 months vs. 7.20 months, HR 0.45, 95% CI 0.14–1.51, p = 0.19). For patients who experienced a progression event after first‐line chemotherapy (N = 50), PFS2 and PFS1 + PFS2 were prolonged in patients who accepted second‐line ICIs‐combined therapy without significant difference (median PFS2 4.00 months vs. 2.43 months, HR 0.59, 95% CI 0.33–1.05, p = 0.070; median PFS1 + PFS2 11.30 months vs. 8.70 months, HR 0.53, 95% CI 0.29–0.98, p = 0.056).ConclusionFirst‐line ICIs plus chemotherapy should be applied in the clinical practice of ES‐SCLC. If patients did not receive ICIs plus chemotherapy in first‐line treatment, therapies that include ICIs in second‐line treatment should be considered.
Property price dynamics and asymmetric effects of economic policy uncertainty: New evidence from the Australian capital cities
Authors: Wadud IKM Mokhtarul , Bashar Omar H. M. N. , Ali Ahmed Huson Joher , Dimovski William 
Published: October 2022

AbstractThis paper examines the long‐run relationship between residential property prices and economic policy uncertainty (EPU) in seven Australian capital cities. Using the panel nonlinear autoregressive distributed lag model, we analyse the asymmetric effect of EPU on Australian house and apartment (unit) prices over the period 2001–2021. The EPU is found to affect property prices negatively; however, the effects of the positive changes in EPU are larger than those of the negative changes in EPU. The evidence of asymmetric effects is particularly strong for unit prices. Our results reveal that interest rates, construction costs and housing loans also drive the long‐run price trends.
Clinical relevance of fibrin membranous structures in the intra‐photoreceptor outer segment separation on spectral domain optical coherence tomography (SD‐OCT) in initial‐onset acute Vogt‐Koyanagi‐Harada disease
Authors: Motegi Shuntaro , Nagura Koichi , Yoneda Keisuke , Harimoto Kozo , Sato Tomohito , Herbort Carl P. , Takeuchi Masaru 
Published: October 2022

AbstractPurposeThe purpose of the study was to investigate clinical relevance of fibrin membranous structure (FMS) in the photoreceptor outer segments on spectral‐domain optical coherence tomography (SD‐OCT) in untreated initial‐onset acute Vogt‐Koyanagi‐Harada (VKH) disease.MethodsClinical charts of 39 patients (78 eyes) diagnosed with initial‐onset VKH disease were retrospectively reviewed. Age, gender, period from the onset of symptoms to first visit, visual acuity (VA), intraocular pressure (IOP), anterior chamber cells, serous retinal detachment (SRD), SD‐OCT findings, as well as fluorescein (FA), and indocyanine green angiography (ICGA) were collected.ResultsFMS was observed in 24 out of 39 VKH patients in either eye (61.5%). VKH patients with FMS (FMS group) were significantly younger and had the shorter period from the onset of symptoms to the first visit compared with those without FMS (non‐FMS group). Mean logMAR VA and proportion of pooling of dye, mean central retinal thickness (CRT) were significantly higher in FMS group than in non‐FMS group. In contrast, hyperfluorescence of the optic disc on FA was more in non‐FMS group than in FMS group. Significant positive correlations between CRT and logMAR VA or IOP were only observed in the FMS group. Total amount of corticosteroids was significantly greater in FMS group than in non‐FMS group. However, there were no significant differences in LogMAR VA and IOP between two groups at 6 months after treatment initiation.ConclusionFMS on SD‐OCT is a critical feature observed in the early stage of initial‐onset acute VKH disease, which is more common in younger patients and is related to the disease activity.
Long‐term safety and efficacy of the anti‐tissue factor pathway inhibitor marstacimab in participants with severe haemophilia: Phase II study results
Authors: Mahlangu Johnny , Luis Lamas Jose , Cristobal Morales Juan , Malan Daniel R. , Teeter John , Charnigo Robert J. , Hwang Eunhee , Arkin Steven 
Published: October 2022

SummaryMarstacimab, an investigational human monoclonal antibody targeting tissue factor pathway inhibitor, demonstrated safety and efficacy in preventing bleeding episodes in patients with haemophilia. This multicentre, open‐label study investigated safety, tolerability, and efficacy of long‐term weekly prophylactic marstacimab treatment in participants with severe haemophilia A and B, with or without inhibitors. Adult participants were enrolled from a previous phase Ib/II study or de novo and assigned to one of two subcutaneous (SC) marstacimab doses: once‐weekly 300 mg or a 300‐mg loading dose followed by once‐weekly 150‐mg doses, for up to 365 days. Study end‐points included safety assessments and annualised bleeding rates (ABRs). Of 20 enrolled participants, 18 completed the study. Overall, 70% of participants had treatment‐emergent adverse events, including injection site reactions, injection site haematoma, and haemarthrosis. No treatment‐related serious adverse events or thrombotic events occurred. Across all dose cohorts, mean and median on‐study ABRs ranged from 0 to 3.6 and 0 to 2.5 bleeding episodes/participant/year respectively, demonstrating comparable efficacy to that observed in the short‐term parent study. No treatment‐induced anti‐drug antibodies were detected. Once‐weekly SC marstacimab prophylaxis was well tolerated, with an acceptable safety profile, and maintained long‐term efficacy up to 365 days. (Clinicaltrials.gov identifier, NCT03363321).
Kinase inhibit region of SOCS3 attenuates IL6‐induced proliferation and astrocytic differentiation of neural stem cells via cross talk between signaling pathways
Authors: An Jing , Tan Ruo‐Lan , Hu Xiao‐Xuan , Cai Zhen‐Lu , Sun Mei‐Qi , Ge Qian , Ma Wen , Li Hui‐Liang , Lu Hai‐Xia 
Published: October 2022

AbstractAimsEfficiency of neural stem cells (NSCs) therapy for brain injury is restricted by astrogliosis around the damaged region, in which JAK2/STAT3 signaling plays a key role. The SOCS3 that can directly inhibit JAK/STAT3 pathway. Here, we investigated the effects of a fusion peptide that combined kinase inhibitory region (KIR) of SOCS3 and virus trans‐activator of transcription (TAT) on biological behavior of cultured NSCs under inflammatory conditions.MethodsNSCs were isolated from embryonic brain of SD rats, TAT‐KIR was synthesized, and penetration rate was evaluated by flow cytometry (FACS). CCK8, immunostaining, and FACS were used to detected of TAT‐KIR on the proliferation of NSCs. The expressions of GFAP and β tubulin III positive cells induced by IL6 with/without TAT‐KIR were examined by immunostaining and Western blotting to observe the NSCs differentiation, and the effect of TAT‐KIR on signaling cross talk was observed by Western blotting.ResultsPenetration rate of TAT‐KIR into primary cultured NSCs was up to 94%. TAT‐KIR did not affect the growth and viability of NSCs. It significantly reduced the NSCs proliferation that enhanced by IL‐6 stimulation via blocking the cell cycle progression from the G0/G1 to S phase. In addition, TAT‐KIR attenuated astrocytic differentiation and kept high level of neuronal differentiation derived from IL‐6‐induced NSCs. The fate of NSCs differentiation under inflammatory conditions was affected by TAT‐KIR, which was associated with synchronous inhibition of STAT3 and AKT, while promoting JNK expression.ConclusionTAT‐KIR mimetic of SOCS3 could be a promising approach for brain repair via regulating the biological behaviors of exogenous NSCs.