bluuebunny/crossref_metadata_2025_split huggingface dataset:
The LIFE BAETULO tool: an Integrated Early Warning System for cities to cope with major climate hazards
Authors: Puentes Montse Martinez , Russo Beniamino , Paindelli Andrea , Bofill Joaquin , Lopez-Pinto Paula Recolons , Perez Rubens Hernandez , Carretero Josep Anton Montes 
Published: December 2022

Abstract
LIFE BAETULO (www.life-baetulo.eu) is a European pilot project funded by the EU LIFE Climate Action programme, coordinated by AQUATEC (AGBAR Group) and with a duration of 2.5 years (from July 2020 to December 2022). The main project solution (an Integrated Early Warning System, IEWS) is implemented as a technical and adaptive means to reduce exposure and vulnerability of urban assets and citizens to climate change. IEWS considers major climate change-induced hazards such as floods, combined sewer overflows (CSOs), storm surges, heatwaves, cold waves, snowfalls, windstorms, air pollution and forest fires. The IEWS platform is built on top of existing infrastructure such as meteorological and weather services, drainage infrastructure monitoring systems and official information channels. It is a multi-risk approach, in contrast with classic sectorial solutions which focus on just one hazard at a time. This paper describes the objectives of the project, the architecture of the IEWS, the methodology used for its validation and the expected results and benefits for the city of Badalona.
Comparative Study of Using Elastic Stable Intramedullary Nail (Esin) Versus Rush Pin in Prophylactic Fixation of Femur &amp; Tibia Fractures Among Children With Osteogenesis Imperfecta Cross-sectional Study
Authors: Khairelseed Mohammed Abdelmohsin , Wad-Bador Mustafa Alsheikh , Alrasheed Mohammed khalid 
Published: December 2022

Abstract
Introduction: Recurrent fractures is the most challenging problem in children with Osteogenesis imperfecta, a variety of surgical methods have been investigated to decrease the incidence of this problem.
Objectives: The aim is to compare between the use of Elastic Stable Intramedullary Nail (ESIN) and Rush Pins in order to decrease fracture frequency and asses the complications associated with each method.
Methods: A descriptive cross-sectional study was conducted in 40 children with Osteogenesis imperfecta, the age of the participants was between 3 - 16 years. 20 children with OI were operated using ESIN and 20 children with OI were operated using Rush pin.
Results:Both techniques are effective in guarding against fractures and correcting the deformities. The rate of nail proximal migration was relatively higher in the ESIN group. The re-fracture rate was lower in the Rush rod group. The rate of recurrence of angular deformities were slightly higher in the ESIN group. The reoperation rate was higher in the ESIN group.
Conclusion: Corrective osteotomy with use of (ESIN) or Rush rods works well in guarding against fractures, but the overall complications and reoperation rate is statistically lower when using Rush rods, however both techniques fail to follow bone growth and have a possible complication such as nail proximal migration, recurrence of deformities and also both techniques do need repeated surgeries.
Recommendations: We recommend further studies to assess the outcome between (ESIN, Rush pin) and Telescoping rods, to assess the longevity of these implants and the precise time for exchange and to correlate between surgical interventions with the concomitant use of Bisphosphonates.
Alterations of knee torsion and tibial tubercle torsion after early patellar dislocation in growing rabbits
Authors: Tang Shiyu , Li Weifeng , Wang Shengjie , Wang Fei 
Published: December 2022

Abstract
Background
Torsional factors were considered to be the risk factors for patellar dislocation. But the effects of patellar dislocation for the development knee torsion and tibial tubercle torsion remains unclear. The animal study aimed to investigate whether early patellar dislocation could lead to the alterations of knee torsion and tibial tubercle torsion in growing rabbits.
Methods
In the study, Thirty rabbits (28 days of age) were randomly assigned to two groups. The experimental group comprised 30 left knees which underwent the surgery-induced patellar lateral dislocation. The control group comprised 30 right knees, rabbits did not undergo surgical procedures. Computed Tomography (CT) scan (fexion 0°) was performed after surgery and 5 months post-operatively. The angle of knee torsion, the angle of tibial tubercle torsion and tibial tuberosity-trochlear groove (TT-TG) distance were measured and evaluated between the control group and the experimental group.
Results
The knee torsion, tibial tubercle torsion and TT-TG were not significantly different between the experimental group and the control group after surgery. However, 5 months post-operatively, the angle of knee torsion in the experimental group (41.52 ± 8.43°) and control Group (3.75 ± 2.13°) were significantly different (P < 0.00). The angle of tibial tubercle torsion was found statistically difference in the experimental group (-9.88 ± 2.35°) versus the control group (2.28 ± 1.57°) (P < 0.00). The TT-TG in the experimental group (7.75 ± 2.64 mm) was significantly increased from that control group (1.08 ± 0.45 mm) (P < 0.00).
Conclusion
The results indicated that early patellar dislocation can lead to alterations of knee torsion and tibial tubercle torsion, showing an increased TT-TG in growing rabbits.
Establishment of recombinase polymerase amplification detection method for Puccinia striiformis f. sp. Tritici
Authors: Liu Yaoxia , Hao Jianyun , Guo Qingyun , Yan Jiahui , Yao Qiang 
Published: December 2022

Abstract
Wheat stripe rust caused by Puccinia striiformis f. sp. tritici(Pst)is an airborne disease that endangers the entire growth period of wheat. In this study, the effect of gene PS4593 of Pst was used as the target gene, that PS4593 effector genes have significant virulence functions in wheat, this effector gene could suppress wheat ETI against an avirulent Pst isolate, and the primers PS-RPA-F and PS-RPA-R, as well as the probe PS-LF-Probe, were designed for recombinase polymerase amplification (RPA) technology. Flow chromatography was combined with the process to establish an RPA detection method for Pst. This method could establish visual detection within 10 min under a constant temperature of 39°C, and the detection results were consistent with those of ordinary PCR analysis. This method only had high specificity for Pst, and the detection limit was 10 fg/µL. In addition, this rapid method could detect Pst from wheat leaves during the field incubation period, which has strong benefits in application. In sum, the RPA detection method established in this study has the favorable characteristics of high efficiency, simple functionality, and rapid and universal practicability, which provides a theoretical basis for the early detection and prevention of Pst.
Controllable topological quantum phase transitions in magnetic material FeBi2Te4
Authors: Zhang Jian-Min , Guo Wen-Ti , Yang Ningjing , Huang Zhigao 
Published: December 2022

Abstract
Here, we report a new intrinsic magnetic topological insulator FeBi2Te4 based on first-principles calculations and it can achieve a rich topological phase under pressure modulation. In the absence of pressure, we predict that both FeBi2Te4 ferromagnetic and antiferromagnetic orders are non-trivial topological insulators. Furthermore, FeBi2Te4 of FM-z ordering will undergo a series of phase transitions from topological insulator to semimetals and then to trivial insulator under pressure. Finally, we further clarify and verify the fact of topological phase transitions in conjunction with low-energy effective model calculations. This topological phase transition process is attributed to the synergy of the magnetic moment and the spin-orbit coupling. The unique topological properties of FeBi2Te4 will be of great interest in driving the development of quantum effects.
3D-GBS: A universal genotyping-by-sequencing approach for genomic selection and other high-throughput low-cost applications in species with small to medium-sized genomes
Authors: Ronne Maxime , Légaré Gaétan , Belzile François , Boyle Brian , Torkamaneh Davoud 
Published: December 2022

Abstract
Despite the increased efficiency of sequencing technologies and the development of reduced-representation sequencing (RRS) approaches allowing high-throughput sequencing (HTS) of multiplexed samples, the per-sample genotyping cost remains the most limiting factor in the context of large-scale studies. For example, in the context of genomic selection (GS), breeders need genome-wide markers to predict the breeding value of large cohorts of progenies, requiring the genotyping of thousands candidates. Here, we introduce 3D-GBS, an optimized GBS procedure, to provide an ultra-high-throughput and ultra-low-cost genotyping solution for species with small to medium-sized genome and illustrate its use in soybean. Using a combination of three restriction enzymes (PstI/NsiI/MspI), the portion of the genome that is captured was reduced 4-fold (compared to a “standard” ApeKI-based protocol) while reducing the number of markers by only 40%. By better focusing the sequencing effort on limited set of restriction fragments, 4-fold more samples can be genotyped at the same minimal depth of coverage. This GBS protocol also resulted in a lower proportion of missing data and provided a more uniform distribution of SNPs across the genome. Moreover, we investigated the optimal number of reads per sample needed to obtain an adequate number of markers for GS and QTL mapping (500-1,000 markers per biparental cross). This optimization allows sequencing costs to be decreased by ~ 92% and ~ 86% for GS and QTL mapping studies, respectively, compared to previously published work. Overall, 3D-GBS represents a unique and affordable solution for applications requiring extremely high-throughput genotyping where cost remains the most limiting factor.
Optimal Energy Management Strategy Based on Neural Network Algorithm for Fuel Cell Hybrid Vehicle Considering Fuel cell Lifetime and Fuel Consumption
Authors: Ahmed OMER Abbaker , Wang Haoping , Tian Yang 
Published: December 2022

Abstract

In order to improve the power performance, fuel cell lifetime, and fuel consumption of fuel cell/battery/ supercapacitor powered-vehicle, this paper proposes a new framework of energy management strategy (EMS) consisting of neural network optimization algorithm (NNOA) optimized fuzzy logic controller-based frequency decoupling and adaptive super-twisting sliding mode control based on nonlinear disturbance observer (ASTSMC-NDOB). In the proposed EMS, frequency decoupling based on adaptive low-pass filter and Harr wavelet transform (HWT) using fuzzy logic controllers (FLCs) are employed to decouple the required power into low, medium, and high-frequency components for fuel cell, battery, and supercapacitor, respectively. The proposed frequency decoupling-based strategy can improve the power performance of the vehicle as well as reduce load stress and power fluctuation on fuel cell. In order to precisely optimize membership functions of suggested FLCs, NNOA is adopted to tune them while minimizing the objective function, considering the hydrogen consumption and constraints on the battery/supercapacitor SOC. Furthermore, in order to achieve robustness and high-precision control, the ASTSMC-NDOB controllers are developed to stabilize the DC bus voltage and force currents of the fuel cell, battery, and supercapacitor to track their obtained reference values. The fuel cell hybrid electric vehicle with proposed EMS is modelled on MATLAB/Simulink, and three driving conditions such as HWFET, UDDS, and WLTP driving schedules are used for evaluation. The findings exhibit that the proposed EMS can effectively improve the fuel economy, reduce power fluctuation on fuel cell, and prolong its lifetime compared to state machine strategy and fuzzy logic control-based EMS.
Solvatochromism and third-order nonlinear optical responses of Azo dye
Authors: Anusha B , Rany D Jeancy , Jeyaram S , Kaviyarasu K 
Published: December 2022

Abstract
Third-order nonlinear optical (NLO) properties of acid black 32 (AB 32); an azo dye is studied by sensitive Z‒scan method. The dye is dissolved into various solvents like methanol, acetone, ethanol, water, DMF and DMSO at 0.01 mM concentration. The diode laser with operating wavelength of 650 nm is used to study the third-order NLO characteristics of AB 32 dye. The effect of solvent spectral characteristics on linear absorption coefficient and third-order NLO features of AB 32 dye is studied and multi-parameter scale known as Kamlet-About-Taft is used to analyze the solvent characteristics on solute molecule. The nonlinear refractive index (n2) and nonlinear absorption coefficient (β) of the dye sample is respectively measured to be the order of 10− 7cm2/W and 10− 2 cm/W. The title sample shows both positive and negative nonlinear absorption (NLA) coefficient owing to the phenomenon of saturable and reverse saturable absorption (RSA), as well as negative nonlinear index of refraction as a result of self-defocusing. The order of third-order NLO susceptibility (χ(3)) of AB 32 dye in different polar solvents is measured to be 10─6 esu. The obtained results propose that AB 32 dye is a suitable material for future NLO applications.
Overexpression of IL-6 and STAT3 May Provide New Insights into Ovine Pulmonary Adenocarcinoma Development
Authors: Toma Corina , Popa Roxana , Ciobanu Lidia , Baldea Ioana , Amorim Irina , Bochynska Diana , Wolfe Alan , Negoescu Andrada , Gal Claudiu , Taulescu Marian 
Published: December 2022

Abstract

Background
Ovine pulmonary adenocarcinoma (OPA) is caused by Jaagsiekte sheep retrovirus (JSRV) and is considered the most suitable animal model for human lung cancer. The precise mechanisms of OPA oncogenesis are still uncertain. Signal transducer and activator of transcription 3 (STAT3) is activated by interleukin-6 (IL-6) in many cancers, but this aspect is unknown in OPA. We aimed to evaluate the expression of IL-6 and STAT3 in OPA for its potential role in pulmonary carcinogenesis.
Results
Twenty cases of JSRV-positive OPA and 9 normal lung tissues from sheep were included in the study. Tissue samples were stained with antibodies for IL-6, STAT3, and JSRV-MA. IL-6 and STAT3 were semi-quantified in OPA and control groups using Western Blot (WB). IL‑6 was expressed in stromal, inflammatory, and epithelial cells in all cases of OPA, while STAT3 expression was restricted to epithelial cells. In the OPA group, the percentage of immunolabelled cells for STAT3 accounted for a mean value of 96%. Using the H-SCORE method, 95% of cases were considered positive for STAT3 expression. Control tissuesshowed multifocal andweak immunoexpression for both markers. Using WB analysis, a highly significant amount of both IL-6 (p=0.0078) and STAT3 (p<0.0001) proteins were detected in lung neoplasms compared to controls.
Conclusions
Our data showed overexpression of IL-6 and STAT3 in OPA in comparison with healthylungs. These results suggest a potential role of IL6-STAT3 in OPA carcinogenesis.
Patterns of Peripartum Depression and Anxiety During the Pre-Vaccine COVID-19 Pandemic
Authors: Altendahl Marie R , Xu Liwen , Asiodu Ifeyinwa , Boscardin John , Gaw Stephanie L , Flaherman Valerie J , Jacoby Vanessa L , Richards Misty C , Krakow Deborah , Afshar Yalda 
Published: December 2022

Abstract

Background: Pregnant people are vulnerable to new or worsening mental health conditions.This study aims to describe prevalence and course of symptomatic depression and anxiety in pregnancy during the pre-vaccine COVID-19 pandemic.
Methods:This is a prospective cohort study of pregnant individuals with known or suspected COVID-19. Participants completed Edinburgh Postnatal Depression Scale (EPDS) and Generalized-Anxiety Disorder-7 (GAD-7) questionnaires at 34weeks gestational age, 6-8weeks postpartum, and 6months postpartum. Prevalence of symptomatic depression and anxiety at each visit was described. Univariable logistic regression analysis was used to determine the association between demographic and clinical factors and symptomatic depression or anxiety
Results: 317 participantswere included.The prevalence of antepartum depression was 14.6%, 10.3%, and 20.6% at 34weeks gestational age, 6-8weeks postpartum, and 6months postpartum, respectively. The rate of anxiety was 15.1%, 10.0%, and 17.3% at 34weeks gestational age, 6-8weeks postpartum, and 6months postpartum, respectively. A prior history of depression and/or anxiety (p’s<0.03), as well as higher EPDS and GAD-7 scores at enrollment (p’s<0.04) associated with depression and anxiety throughout pregnancy and the postpartum period. Quarantining during pregnancy was associated with symptomatic anxiety at 34weeks gestational age in univariate (P=0.027) analyses. COVID-19 diagnosis and hospitalization were not associated with depression or anxiety.
Conclusions: Depression and anxiety were prevalent throughout pregnancy and the postpartum period, particularly in those with prior depression and/or anxiety and who quarantined. Strategies that target social isolation may mitigate potential adverse consequences for pregnant people, and continued vigilance in recognition of depression and anxiety in pregnancy should be considered.
The COMPASS subunit Spp1 protects nascent DNA at stalled replication fork barrier by limiting DNA availability to nucleases
Authors: Ghaddar Nagham , Corda Yves , Luciano Pierre , Galli Martina , Doksani Ylli , Geli Vincent 
Published: December 2022

Abstract
Homologous recombination factors play a crucial role in protecting nascent DNA during replication but the role of chromatin in this process is largely unknown. Here, we used the bacterial Tus/Ter barrier known to induce a site-specific replication fork stalling in S. cerevisiae. We report that the COMPASS subunit Spp1 is recruited behind the stalled replication fork independently of its interaction with Set1. Spp1 chromatin recruitment depends on the interaction of the Spp1 PHD domain with H3K4me3 parental histones deposited behind the stalled fork. Its recruitment prevents accumulation of ssDNA at the stalled fork by restricting the access of Exo1. We further show that deleting SPP1 accelerates fork progression and increase mutation rate upstream the barrier consistent with ssDNA accumulation. Finally, we report that Spp1 protects nascent DNA at challenged replication forks. We propose that Spp1 limits remodeling of the fork that ultimately limits nascent DNA availability to nucleases.
Du Fort-Frankel Finite Difference Scheme for Solving of Oxygen Diffusion Problem Inside One Cell
Authors: BOUREGHDA Abdellatif , Djellab Nadjate 
Published: December 2022

Abstract
In this paper, we use the well-known Du Fort-Frankel finite difference scheme to solve the oxygen diffusion problem inside one cell which is modeled by an initial moving boundary value problem for one dimensional time-dependent partial differential equation. The main problem consists in tracking the moving boundary that represents the oxygen penetration depth inside the cell. We explore the possibilities of numerical approximation of the problem posed by the different formulations. Some numerical experiments are also provided with comparisons with analytical solution.The theoretical analysis is given for the numerical scheme. It is shown that all the results obtained by this method are compared with earlier authors.
AMS Subject Classification: 35R35; 35R37; 80A22; 65M06; 65N06.
Biomechanical evaluation of implant system fixed dentures support in atrophic maxilla
Authors: Coelho Katherine , Mota Leonardo , Lameira Aladim , Vedana Deborah , Zavaglia Cecília , Dias Carmen 
Published: December 2022

Abstract
Patients with atrophic maxilla are a challenge, since this condition can compromise the installation of implants. Hybrid implants system made by CAD/CAM, installed in the zygomatic and canine pillars bilaterally. The AL system consists of mini plates connected in a prosthetic abutment that is screwed into an implant-supported complete denture. There was performed a biomechanical evaluation of the AL system under mastication load simulation. A model of a patient's bone was built using In Vesalius software, exported, and treated in a CAD system. The AL implants and the prosthesis fixation bar were modeled based on the Bio model’s geometry. A structural static simulation of the bar was carried out and the supportive reactions were applied on the implants. The simulation was performed for a critical chewing load of 756 N. In this case, the maximum von Mises tension in the fixation bar and the minimum safety factor were respectively 366 MPa and 1.91. In a simulation of a 5 times lower load total edentulous chewing load, the safety factor was 9.55 and 17.10 for the fixation bar and the implants. The fixation bar and implants have the capacity to withstand the stresses to which they will be subjected during chewing.
Health facilities preparedness to deliver maternal and newborn health care in Kilifi and Kisii Counties, Kenya
Authors: Orwa James , Temmerman Marleen , Nyaga Lucy , Mulama Kennedy , Luchters Stanley 
Published: December 2022

Abstract
Introduction: Health facility preparedness to deliver quality maternal and newborn care reduces maternal and newborn morbidity and mortality by avoiding the three delays (delay in deciding to seek care from a skilled attendant by pregnant woman; delay in reaching the facility with capacity to offer basic emergency obstetric care; and delay in receiving emergency care upon reaching a health facility). Rapid assessment and review of previous health records has shown that 16 health facilities in rural Kenya had poor maternal and newborn indicators. As a result, support was given to these facilities by providing basic emergency obstetric and newborn care (BEmONC) and comprehensive emergency obstetric and newborn care (CEmONC) training to providers, provision of equipment and supplies, and strengthening referral linkages. This study described the preparedness of the facilities to deliver maternal and newborn health care services at the end of the project implementation.
Methods: A descriptive cross-sectional study was conducted in targeted rural counties of Kilifi and Kisii counties in December 2019 covering 16 Government of Kenya (GoK) health facilities to describe the preparedness of the facilities to deliver maternal and newborn healthcare services by examining the availability of drugs, commodities, equipment, staffing, general requirements (water and electricity, and guidelines), and the ability to perform. The results of the assessment are described using frequency and percentages, and comparative synthesis.
Results:
All of the 16 facilities were offering routine ANC and normal vaginal delivery services, however only two were providing CEmONC services. Most of the essential medicines and commodities were available in most of the health facilities as well as the required equipment. BEmONC and CEmONC guidelines were available in Kilifi health facilities and none in Kisii. There was only one staff in each county available 24/7 for Caesarian Section (CS) and only one anesthetist available in Kilifi. Electricity was available in all the facilities, however only half had secondary power supply. All the facilities offering CS were equipped with generators as a secondary power back-up.
Conclusion:
The health facilities reported availability of most of the drugs, commodities, and equipment than on general requirements as per their level of operation, however staffing and guidelines were limited. Facilities in Kilifi performed better than in Kisii. To deliver quality maternal and newborn health services, more support is required towards general infrastructure and human resources. Continuous monitoring of these services will help in the allocation of resources based on the need of the health facilities.