bluuebunny/crossref_metadata_2025_split huggingface dataset:
Provenance documentation to enable explainable and trustworthy AI: A literature review
Authors: Kale Amruta , Nguyen Tin , Harris Frederick C. , Li Chenhao , Zhang Jiyin , Ma Xiaogang 
Published: February 2022

ABSTRACTRecently artificial intelligence (AI) and machine learning (ML) models have demonstrated remarkable progress with applications developed in various domains. It is also increasingly discussed that AI and ML models and applications should be transparent, explainable, and trustworthy. Accordingly, the field of Explainable AI (XAI) is expanding rapidly. XAI holds substantial promise for improving trust and transparency in AI-based systems by explaining how complex models such as the deep neural network (DNN) produces their outcomes. Moreover, many researchers and practitioners consider that using provenance to explain these complex models will help improve transparency in AI-based systems. In this paper, we conduct a systematic literature review of provenance, XAI, and trustworthy AI (TAI) to explain the fundamental concepts and illustrate the potential of using provenance as a medium to help accomplish explainability in AI-based systems. Moreover, we also discuss the patterns of recent developments in this area and offer a vision for research in the near future. We hope this literature review will serve as a starting point for scholars and practitioners interested in learning about essential components of provenance, XAI, and TAI.
Jubilee Debt Cancellation and Luke’s Gospel
Authors: Luthy Christopher J. 
Published: February 2022

Abstract
This study questions the argument that references to debt in Luke’s gospel (particularly Luke 6:34–36; 7:36–50; 11:2–4; and 16:1–9) should be viewed in relation to the biblical Jubilee. After a survey of Jubilee debt cancellation in the Old Testament and Second Temple literature, it is concluded that debt cancellation and the Jubilee were usually understood to be separate concepts. It is then argued that this is consistent with how debt texts in Luke’s gospel are presented; there are no words or syntactical patterns which suggest reliance on Jubilee traditions. Finally, it is argued that the concept of debt in Luke’s gospel served a variety of purposes, none of which need to be viewed in reference to the Jubilee.
Marx America Gramsci Again: Understanding Trumpism through Bonapartism and Caesarism
Authors: Meckler Jeremy 
Published: February 2022

Abstract
In The Eighteenth Brumaire Karl Marx uses the concept of “Bonapartism” to explain the success of the “grotesque mediocrity” Louis-Napoléon Bonaparte, emphasizing the farcical connection between Louis-Napoléon and his famous uncle. Antonio Gramsci reformulates this concept as “Caesarism” to describe Benito Mussolini’s rise to power, linking Mussolini’s regressive utopianism to the Roman Empire and emphasizing the mythic nature of such rhetorical strategies. Gramsci complicates and expands Marx’s Bonapartism, making it more useful for understanding Trumpism’s tactics. Make America Great Again calls for a return to a mythic glory based on nostalgia for an imagined era, and the events of January 6 demonstrate how this ideology can be weaponized. Through a close reading of Marx and Gramsci’s formulations, this paper develops a structural understanding of the necessary preconditions for Trumpist populism, but also understands Trumpism’s origins as evidence of a revolutionary mass sentiment that could be channeled in progressive directions.
Description of the complete larval development of Lysmata amboinensis (De Man) (Decapoda: Lysmatidae) reared under laboratory conditions
Authors: DE SOUSA LÍGIA F. , MARQUES DANIEL , LEANDRO SÉRGIO MIGUEL , SANTOS ANTONINA DOS 
Published: February 2022

Complete larval morphological descriptions are currently only known for three of the 48 species of genus Lysmata. The present study describes and illustrates the larval development of Lysmata amboinensis (De Man) reared under laboratory conditions. Lysmata amboinensis larval development is composed by a total of ten zoea and a decapodite stage.
The first zoeal stage larvae presents sessile eyes, a carapace with a pterigostomial spine and anterio-ventral marginal denticles, a long, slender, and pointed rostrum, an antennal exopod terminally articled, a pleon with five somites, the fifth one bearing a pair of dorso-lateral spines on the posterior margin, and a triangular shaped telson with 7+7 posterior processes. The decapodite resembles a smaller adult and has extremely long antennas (more than twice the total length of the decapodite), the first two pair of pereiopods with chela, first four pairs of pereiopods with reduced and entire exopods, and fully developed pleopods.
The morphological features of L. amboinensis are compared with those currently available for the larval stage of the genus Lysmata.
Mariátegui and Dependency Theory: Reviewing a Powerful Inheritance in Latin American Thought
Authors: Acosta Alberto , Cajas-Guijarro John 
Published: February 2022

A review of the multiple approaches to dependency theory alongside some of the thoughts on dependency of José Carlos Mariátegui highlights the contributions that Mariátegui could make to the deepening of that theory and even the opening of new paths and the theoretical affinity to the work of later scholars. Reconstruction of Mariátegui’s and other critical approaches to capitalism, including the postdevelopmentalist, is an urgent task. Una reseña del pensamiento dependentista desde sus múltiples aproximaciones, complementada con una revisión de varias intuiciones sobre la dependencia dejadas por José Carlos Mariátegui, hace resaltar los aportes que Mariátegui podría brindar para profundizar e incluso abrir nuevos senderos a las teorías de la dependencia. Una reconstrucción de las teorías tanto de Mariátegui como de otros referentes del pensamiento crítico al capitalismo, incluso en clave posdesarrollista, es una tarea urgente.
Long‐term Oncologic Results and Voice Outcomes in Patients With Glottic Cancer After Modified Type III Cordectomy
Authors: Liu Chin‐Hsuan , Chien Pei‐Ju , Hung Li‐Ting , Wang Li‐Mei , Kao Ya‐Chuan , Tsai Yueh‐Ju , Chu Pen‐Yuan 
Published: February 2022

ObjectiveTransoral laser microsurgery and radiotherapy provide high and comparable cure rates for the treatment of early glottic cancer. However, the voice outcomes after treatment remain controversial. A modified type III cordectomy technique was proposed in 2006, and preliminary results showed it to be an oncologically safe method with satisfactory voice outcomes. This study aimed to evaluate oncologic and voice outcomes after long‐term follow‐up of these patients.Study DesignRetrospective cohort study.SettingTertiary care academic center.MethodsBetween 2006 and 2018, 42 patients with glottic cancer underwent a modified type III cordectomy. This technique resected the tumor and upper part of the vocal folds and preserved the lower part of the vocalis muscle as a scaffold to improve glottis closure. The oncologic results and voice outcomes were evaluated at a median follow‐up of 68 months.ResultsThe primary tumor stages included 13 T1 (31%), 26 T2 (64%), and 3 T3 (7%). Eight patients (19%) had local recurrence, and 6 underwent successful salvage with transoral laser microsurgery with or without postoperative radiotherapy with laryngeal preservation. The 5‐year rate of local control was 80%; laryngeal preservation, 95%; overall survival, 89%; and disease‐specific survival, 97%. The final laryngeal preservation rate was 95% (40/42). The voice outcomes were satisfactory and comparable to those of patients who underwent type I and II cordectomies.ConclusionThe modified type III cordectomy has been proven to be an oncologically safe method with satisfactory voice outcomes after long‐term follow‐up in selected cases of early glottic cancer.
Effectiveness of adding virtual reality to physiotherapeutic treatment in patients with total hip arthroplasty. A randomized controlled trial
Authors: Zavala-González Jonathan , Martínez Diego , Gutiérrez-Espinoza Héctor 
Published: February 2022

Objective To determine the clinical effectiveness of adding virtual reality via the Nintendo Wii console and its Wii Balance Board to physiotherapy treatment in patients with total hip arthroplasty. Design Randomized controlled trial. Setting Clinical Hospital San Borja Arriaran, Santiago, Chile. Participants A total of 73 patients over 50 years of age with total hip arthroplasty were randomly allocated to two groups. Interventions The control group (n = 37) received 6 weeks of physiotherapy treatment; the intervention group (n = 36) received the same treatment plus virtual reality exercises with the Nintendo Wii console. Outcome measures The two groups were assessed at baseline and after the 6 weeks of treatment. The primary outcome assessed was the function with the WOMAC questionnaire. The secondary outcomes were the Berg Balance Scale, distance covered with the six-minute walk test, and difference in weight load on the lower extremities. Results A total of 73 patients, 37 patients in the control group (20 women; mean age of 70.9 ± 9.16 years) and 36 patients in the intervention group (18 women; mean age of 70.39 ± 9.02 years) were analyzed. At the end of the treatment, the difference between groups for the total WOMAC score was −10.4 points ( p = 0.00), 4.7 points ( p = 0.00) for the Berg Balance Scale, and 45.2 mt ( p = 0.00) for the six-minute walk test All differences were in favor of the intervention group. Conclusions In the short term, the addition of virtual reality via the Nintendo Wii and its Wii Balance Board platform showed statistically significant differences in the function of patients with total hip replacement, but these differences were not minimally clinically important. Trial registration: This research was registered in the Clinical Trials Registry of Australia and New Zealand, with reference ACTRN12618001252202.
A randomized controlled trial of 3,4-methylenedioxymethamphetamine (MDMA) and fear extinction retention in healthy adults
Authors: Maples-Keller Jessica L , Norrholm Seth D , Burton Mark , Reiff Collin , Coghlan Callan , Jovanovic Tanja , Yasinski Carly , Jarboe Kathleen , Rakofsky Jeffrey , Rauch Sheila , Dunlop Boadie W , Rothbaum Barbara O 
Published: February 2022

Background: Fear conditioning and extinction are well-characterized cross-species models of fear-related posttraumatic stress disorder (PTSD) symptoms, and recent animal data suggest that 3,4-methylenedioxymethamphetamine (MDMA) enhances fear extinction retention. Aims: This study investigated the effect of MDMA on fear learning, extinction training, and retention in healthy humans. Methods: The study involved a randomized placebo-controlled, two-group, parallel design trial in a sample of healthy adults, age 21–55 recruited from a major metropolitan area. The experimental paradigm included a fear acquisition session followed by an extinction training session 24 hours later, and 2 hours after study drug administration. Fear extinction retention was measured 48 hours after extinction training. Participants ( N = 34; 70.6% male and 29.4% female) were randomly assigned in 1:1 ratio to 100 mg MDMA or placebo. All randomized participants completed the trial and were included in primary analyses. Safety was monitored via adverse events and vital signs. MDMA was well-tolerated with no serious adverse events. Results: Results indicated a significant main effect of session between extinction training and retention with no significant group differences. Significantly more participants in the MDMA group retained extinction learning compared to the placebo group (χ2 = 7.29, p = 0.007). Conclusion: Although we did not observe the hypothesized facilitation of extinction retention, the findings from this initial human trial provide compelling rationale to continue to explore the potential for MDMA to impact extinction retention. Clinical Trials Registry Name and Identifier: Evaluation of MDMA on Startle Response (NCT0318176) https://clinicaltrials.gov/ct2/show/NCT03181763?term = MDMA&draw = 2&rank = 9
Prevalence of neck pain in migraine: A systematic review and meta-analysis
Authors: Al-Khazali Haidar Muhsen , Younis Samaira , Al-Sayegh Zainab , Ashina Sait , Ashina Messoud , Schytz Henrik W 
Published: February 2022

Background Neck pain is a frequent complaint among patients with migraine and seems to be correlated with the headache frequency. Neck pain is more common in patients with chronic migraine compared to episodic migraine. However, prevalence of neck pain in patients with migraine varies among studies. Objective To estimate the prevalence of neck pain in patients with migraine and non-headache controls in observational studies. Methods A systematic literature search on PubMed and Embase was conducted to identify studies reporting prevalence of neck pain in migraine patients. This review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Data was extracted by two independent investigators and results were pooled using random-effects meta-analysis. The protocol was registered with PROSPERO (CRD42021264898). Results The search identified 2490 citations of which 30 contained relevant original population based and clinic-based data. Among these, 24 studies provided data eligible for the analysis. The meta-analysis for clinic-based studies demonstrated that the pooled relative frequency of neck pain was 77.0% (95% CI: 69.0–86.4) in the migraine group and 23.2% (95% CI:18.6–28.5) in the non-headache control group. Neck pain was more frequent in patients with chronic migraine (87.0%, 95% CI: 77.0–93.0) compared to episodic migraine (77.0%, 95% CI: 69.0–84.0). Neck pain was 12 times more prevalent in migraine patients compared to non-headache controls and two times more prevalent in patients with chronic migraine compared to episodic migraine. The calculated heterogeneity (I2 values) ranged from 61.3% to 72.0%. Conclusion Neck pain is a frequent complaint among patients with migraine. The heterogeneity among the studies emphasize important aspects to consider in future research of neck pain in migraine to improve our understanding of the driving mechanisms of neck pain in a major group of migraine patients.
Facial expressions modulate pain perception in patients with chronic migraine
Authors: Matamala-Gomez Marta , Bottiroli Sara , Sances Grazia , Allena Marta , De Icco Roberto , Ghiotto Natascia , Guaschino Elena , Sandrini Giorgio , Tassorelli Cristina 
Published: February 2022

Aim First, we investigated whether the exposure to different visual feedback conditions may modulate pain perception by means of visual induced analgesia in patients with chronic migraine. Second, to comprehend the way emotional face expressions could induce visual analgesia, we evaluated the degree of identification with the four experimental conditions. Methods In a 1 × 4 within-subject study design, 38 female chronic migraine patients were exposed to different visual stimuli – positive face, neutral face, negative face, and control (white screen) – during a migraine attack. Visual stimuli were presented 3 times in a randomized order (each condition lasted 40 seconds). Migraine pain ratings and identification scores were assessed immediately after the observation of each visual condition. Results We observed a significant difference in pain ratings between the positive (median: 30, 95% CI 26.69 to 38.20) and the negative (median: 30, 95% CI 33.09 to 44.13) ( z = −4.46, p < 0.0001) facial expressions or the neutral facial expression (median: 30, 95% CI 31.89 to 42.41) ( z = 3.41, p < 0.001). Participants identified more with the neutral face condition than with the other conditions. Conclusions Observation of a positive emotional face resulted sufficient to modulate pain perception possibly via the mediation of emotion regulation for positive emotions. This study paves the way for the integration of new cognitive behavioural interventions based on the adoption of visual induced analgesia to further control pain perception in chronic migraine patients.
Studies on microstructural characteristics and mechanical properties of hybrid Al-4032 AMC reinforced with SiC and granite marble powder
Authors: Saini Pardeep , Singh Pradeep K 
Published: February 2022

The present work reports the impact of granite marble powder (GMP) and SiC on the physical, microstructural, and mechanical characterization of the hybrid aluminium-based metal matrix composite (AMC). Al-4032/SiC/GMP composites with 4, 6, and 8 weight % of SiC and GMP (equal proportion) have been fabricated through stir casting. The impact on properties like density, porosity, ultimate tensile strength (UTS), elongation, microhardness, and impact strength were analyzed according to ASTM standards. A maximum of 1.07% increase in theoretical density and a maximum of 4.86% decrease in experimental density have been recorded for 8% reinforcement. Microstructure of the as-cast specimens were analyzed using optical microscope (OM), XRD (X-ray diffraction), and SEM (scanning electron microscope) equipped with EDS (energy dispersive spectroscopy). Owing to ceramic particles, mechanical properties like UTS, microhardness, and impact strength of the AMC got enhanced from 69.4 MPa to 146 MPa, 131.4 HV to 190.2 HV, and 22.4 J to 32.8 J, respectively.
Description of damage in different clusters of patients with antiphospholipid syndrome
Authors: Uludağ Ömer , Çene Erhan , Gurel Erdem , Çetin Çiğdem , Bektaş Murat , Yalçınkaya Yasemin , Diz-Küçükkaya Reyhan , Gül Ahmet , Inanç Murat , Artim-Esen Bahar 
Published: February 2022

Objective To identify the different clinical phenotypes of antiphospholipid syndrome (APS) by using cluster analysis and describe cumulative damage of disease clusters. Methods This retrospective study includes patients with APS (±systemic lupus erythematosus (SLE)). Two-step cluster analysis was applied by considering clinical data. Damage was calculated for all patients by applying damage index for APS (DIAPS). Results A total of 237 patients (198 females; median age of 43 years; median follow-up of 9.5 years) were classified into four clusters. Cluster 1 ( n = 74) consisted of older patients with arterial-predominant thrombosis, livedo reticularis, and increased cardiovascular risk; cluster 2 ( n = 70) of SLE+APS patients with thrombocytopenia and heart valve disease; cluster 3 ( n = 59) of patients with venous-predominant thrombosis, less extra-criteria manifestations; and cluster 4 ( n = 34) of patients with only pregnancy morbidity with lower frequency of extra-criteria features and cardiovascular risk. Patients with SLE+APS ( n = 123) had the highest mean DIAPS. Regarding clusters, 1 and 2 had high cumulative damage. While cumulative survival rates of clusters did not differ, cluster 2 and 3 had lower survival rates at further years. There was no correlation between DIAPS and mortality. Conclusion SLE+APS patients with extra-criteria manifestations and older APS patients with arterial thrombosis and increased cardiovascular risk have higher cumulative damage. Effective treatment of SLE disease activity and control of cardiovascular risk may help to reduce cumulative damage in these patients.
Towards real time release testing of Shuxuening injection based on near infrared spectroscopy and accuracy profile
Authors: Ouyang Xiaojie , Zhan Shuyi , Tang Min , Wang Shumei , Liang Shengwang , Sun Fei 
Published: February 2022

Real time release testing (RTRT) has been applied in the pharmaceutical process to ensure the high quality of finished products. Near infrared (NIR) spectroscopy is one of the primary analytical methods to implement RTRT. In this study, an NIR quantitative method was developed to determine the content of total flavonol glycosides in Shuxuening injection and validated by the accuracy profile approach. Combining the NIR validation with quality specification limits, a reliable RTRT method was constructed. Shuxuening injection samples of different concentrations were prepared and characterized by NIR spectroscopy. A first-order Savitzky–Golay derivative was used to pretreat the NIR spectra, and the competitive adaptive reweighted sampling method was used to select the feature variables. Partial least squares (PLS) regression was used to build the NIR quantitative model. The trueness, precision, and accuracy of the developed NIR models were validated by accuracy profile, and the measurement uncertainty was also estimated. Finally, the unreliability graph as a decision tool was established to avoid risk, enabling correct decision making to release of Shuxuening injection. The root mean square error of calibration, root mean square error of cross validation, root mean square error of prediction, and the ratio of prediction to deviation of the PLS model were 19.6 μg·mL−1, 20.9 μg·mL−1, 29.9 μg·mL−1, and 12.2, respectively, indicating the NIR quantitative model had good predictive performance. The validation results prove that the precision, trueness, and accuracy of the NIR quantitative model were within the acceptable limits. Based on the unreliability graph, the decision to release Shuxuening injection was satisfied, if the prediction of total flavonol glycosides fell into the range from 783 μg·mL−1 to 900 μg·mL−1. The RTRT method for Shuxuening injection based on NIR spectroscopy and accuracy profile can improve the efficiency and accuracy of quality control.
An Update on the Status of Vaccine Development for SARS-CoV-2 Including Variants. Practical Considerations for COVID-19 Special Populations
Authors: Kantarcioglu Bulent , Iqbal Omer , Lewis Joseph , Carter Charles A. , Singh Meharvan , Lievano Fabio , Ligocki Mark , Jeske Walter , Adiguzel Cafer , Gerotziafas Grigoris T. , Fareed Jawed 
Published: February 2022

The progress in the development of various vaccine platforms against SARS-CoV-2 have been rather remarkable owing to advancement in molecular and biologic sciences. Most of the current vaccines and those in development focus on targeting the viral spike proteins by generating antibodies of varying spectrum. These vaccines represent a variety of platforms including whole virus vaccines, viral vector vaccines, nucleic acid vaccines representing RNA, DNA, and their hybrid forms. The therapeutic efficacy of these vaccines varies owing to their pharmacodynamic individualities. COVID-19 variants are capable of inducing different pathologic responses and some of which may be resistant to antibodies generated by current vaccines. The current clinical use of these vaccines has been through emergency use authorization until recently. Moreover, the efficacy and safety of these vaccines have been tested in substantial numbers of individuals but studies in special populations that better reflect the global population are pending results. These specialized populations include young children, immunocompromised patients, pregnant individuals, and other specialized groups. Combination approaches, molecularly modified vaccination approaches, and vaccines conferring longer periods of immunity are being currently being investigated, as well as pharmacovigilance studies. The continual transformation of SARS-CoV-2 and its variants are of concern along with the breakthrough infections. These considerations pose new challenges for the development of vaccination platforms. For this purpose, booster doses, combination vaccine approaches, and other modalities are being discussed. This review provides an updated account of currently available vaccines and those in advanced development with reference to their composition and mechanisms of action. A discussion on the use of vaccines in special populations including immunocompromised patients, pregnant women and other specialized populations are also included.