bluuebunny/crossref_metadata_2025_split huggingface dataset:
Competencies of Effective Managers in the Era of Fourth Industrial Revolution
Authors: HRYNCHAK N. , IVASHCHENKO О. , BULAKH Т. , DISHLEVIY R. 
Published: January 2022

The article contains results of an analysis of key competencies required by effective managers in our time of massive digitalization caused by the fourth industrial revolution. The essential meaning of competencies and digital competencies required by a manager in our time is outlined. It is shown that competencies of an effective managers were evolved in parallel with four industrial revolutions: while in the era of the first industrial revolution physical skills of the personnel were crucial, the second industrial revolution pushed up the development of cognitive skills, the third industrial revolution was associated with automation of industrial processes, and the fourth industrial revolution relies on digital competencies.
It is argued that when an organization strives to be competitive in future, it has to focus on competence building of its managers. The analysis revealed that an effective manager in the era of the fourth industrial revolution needs to have and develop the following categories of competencies: basic competencies (creativity and innovative way of thinking, emotional and social intellect, communicability, cultural intellect, critical thinking, self-criticism and integrity); digital competencies (ability for analytical thinking, computational thinking, ability for cooperation in the virtual environment, flexibility and adaptability, ability for self-education), and the competencies related with ability to operate in the network, cognitive flexibility, ability to find comprehensive solutions to the problems and to give sound assessment of the team members’ contributions in the project performance.
Energy Efficiency of the Ukrainan Economy: Problems and Prospects
Authors: LUNOVA Т. 
Published: January 2022

The purpose of the article is to assess the current state of energy efficiency of Ukrainian economy and outline ways to increase it.
The problem of high energy intensity of Ukrainian GDP is studied. The Ukraine’s position in the world on this indicator is analyzed. It is established that the main reasons for low energy efficiency of the national economy are the depreciation of fixed assets of large industrial enterprises; technological losses of electricity in the networks, which account for 11.6% of the total supply; lack of financial resources for the implementation of energy efficiency measures, lack of a systematic approach to energy consumption.
The experience of implementation of Smart Grid projects of intellectual energy in the countries of the world is considered. It is established that more than 2930 organizations from 50 countries of the world take part in these projects. The main investments in Smart Grid projects are concentrated in: Denmark, Germany, Spain, France, Great Britain, France, Belgium and Sweden. In the European Union, companies implementing such innovative projects are reimbursed half of the costs of their implementation.
The directions of the state energy saving policy in Ukraine are described: adoption of the Law of Ukraine “On Energy Saving”; creation of the State Agency for Energy Efficiency and Energy Saving of Ukraine; approval of the Energy Strategy of Ukraine for the period up to 2035; development of the draft Concept of integrated implementation of Smart Grid in Ukraine until 2035, which aims to reduce technological losses of electricity to 7.5%.
It is concluded that it is necessary to create energy management systems (SEM) at large enterprises, which will optimize the volume and modes of electricity consumption and reduce its losses in the production process. The main functions of SEM, principles of energy efficiency management at the enterprise and functions of the energy manager are defined.
How the Structure of GDP of Ukraine Responded to COVID-19
Authors: Motoryn R. М. , Motoryna Т. М. , Prykhodko К. R. 
Published: January 2022

The impact of the COVID-19 pandemic on the structure of Ukrainian GDP is studied, with summing up the causes of impact occurrence and mechanisms of manifestation. The peculiarities of the pandemic’s impact on the institutional and industrial structure of economy in the specific conditions of Ukraine are revealed. The dynamics of the structure of the domestic GDP in the conditions of pandemic is analyzed.
The contribution of the sectors of non-financial corporations, households, financial corporations and government in the Ukrainian GDP is highlighted. It is shown that the increased economic activity of non-financial sector resulted in a growth in dividends, royalties and other components of the property income. However, financial corporations, general government and households were losing property incomes, first of all due to the decreased interest rate of the National Bank of Ukraine, which reduced incomes of financial corporations in form of interests on loans, bond yields of the government, and deposit incomes of households.
Problems of redistribution of primary incomes of sectors by the financial system are discussed. Emphasis is made on the banking sector. With the pandemic shattering the financial health of banks, they started to increase the commission fees to compensate the losses. This process is expected to go on in the forthcoming months. At the initial period of the economy freezing, banks did not feel its outcomes as severely as sectors like tourism, transport or culture. The dynamics of GDP structure by economic activity is analyzed by three dimensions given the available national accounts data of the State Statistics Service of Ukraine. The analysis covers, first, the dynamics of GDP structure by economic activity in absolute terms, second, the dynamics of GDP structure in current prices, and, third, the dynamics of GDP structure in last year prices, thus eliminating the price effect for the dynamics of GDP. The adverse impact of the dynamics of prices occurred in the following sectors: manufacturing; health care and social aid; education; water supply, sanitation, waste treatment; transport; storage facilities; postal and courier activities; temporary accommodation and public catering. While the grown prices for these sectors’ products increased their weight in GDP in current prices, this weight was smaller in comparable prices.
The study was conducted on the basis of research publications and material of the State Statistics Service of Ukraine and professional organizations. Desk research method was used in the process, i. e. analysis of available data, involving extraction and exploration of the already available information, which is the basis for producing new data in line of the author’s research objective.
Advanced Methods of Bank Risk Management
Authors: Kolesnik Ya. V. 
Published: January 2022

Main approaches to building up a system for management of financial risks faced by banks are discussed. It is shown that risk management in banking is a complex process aimed at identification of risk sources, assessment and minimization of the effects of the identified risks, in order to reduce their adverse impact on the commercial bank performance. The main objective of banks is defined as maintaining the constant balance between the needs in resources and the capabilities of their acquisition. The importance and necessity of measurement and quantification of the level of specific types of risk and/or the cumulative risk is highlighted. Special emphasis is made on the credit risk caused by the probability of bank counterparties’ failure to fulfill their obligations. Its usual consequence is failure to repay (fully or partially) the debt principal and the interests in terms specified by the contract. It is shown that the level of credit risk in a country is conditional on macro- and microeconomic factors, with highlighting their effects. It is demonstrated that the adverse impact of inflation is the most explicit one, as it provokes devaluation of bank assets which major share is funds and financial investment. Functional risks are caused by subjective and objective factors, and by system failures, and they cover strategic risks related with mistakes in strategic management. Financial risks can trigger unpredictable change in the amount, profitability and structure of bank assets and liabilities. The liquidity risk can occur when a bank has insufficient or surplus liquidity. The insufficient liquidity can provoke bank insolvency. The inflation risk has ambiguous effects for bank operation.
The successful risk management is a critically important condition for competitiveness and reliability of any financial organization; its objective is to identify and prevent potential adverse events, and to find the tools for minimization of their effects as part of the elaborated methodology of management. Further research devoted to problems of risks faced by the Ukrainian banking system and economic analysis of specific risks will help outline the ways of cost reduction in the banking sector and constantly extend the range of bank services.
The Structure of Labor Market as an Indicator of Shadow Economy
Authors: Gerasymenko S. S. 
Published: January 2022

The article is focused on analysis of factors that determine the patterns of market economy operation. Ukraine, like the other world, has witnessed more than one financial and economic crisis since it gained independence. Its manifestations are the reduced GDP, the worsened financial performance in the business sector, the shrinking real income of the population and the declining investment activity. Search for the factors provoking crises and ways to mitigate their effects has been a central subject of studies conducted by many researchers. However, their research effort has not paid adequate attention to analysis of causal links between the so called shadow economy and the parameters embedded by researchers in models of the modern economy. Methods for shadow economy assessment are author-specific, with quite distinct momentary results. Also, an analysis of shadow economy trends has been virtually lacking, which does not allow to account for its contribution in the formation of market economy patterns, although it seems to be quite significant given a large share of the shadow economy sector at national and global level.
The possibility for assessment of the shadow economy in its relation with the labor market structure that can be characterized by developed robust models is substantiated. Apart from description of the current labor market performance, it also allows for its forecasting. Hence, the elaboration of measures aimed to improve the situation on the labor market enables to reduce the share of shadow economy and, considering the other factors, to halt the occurrence of economic crisis or mitigate its effects for the economy and public welfare.
The main problem that have limited so far the application of the abovementioned approach to solving the problems of economic forecasting was lack of consensus about the classification of the economic system components as either factors or results. This article is an author’s attempt to demonstrate that the structure of labor market and the share of unemployment in particular, is largely dependent on the role of shadow sector in the domestic economy. By employing models characterizing unemployment, this allows to determine the share of its variation related with the shadow economy, and to proceed with forecasting the share of shadow sector in the economy and its impact on the formation of the national economy patterns. Determining the measure and direction of this impact on a domestic economy has to be the next phase of the study.
Aplikasi Metode Tasmi' Dan Muraja'ah Dalam Program Tahfidzul Quran Pada Santriwati di Ma'had Tahfidz Hidayatul Qur'an Desa Puding Besar
Authors: Hendrawati Wiwik , Rosidi Rosidi , Sumar Sumar 
Published: January 2022

Penelitian ini bertujuan untuk mengetahui penerapan metode tasmi’ dan muraja’ah dalam program tahfidzul Qur’an pada santriwati di Ma’had Tahfidz Hidayatul Qur’an Desa Puding Besar dan untuk mengetahui keberhasilan program tahfidzul qur’an dengan menggunakan metode tasmi’ dan muraja’ah pada santriwati di Ma’had Tahfidz Hidayatul Qur’an Desa Puding Besar. Metode penelitian ialah kualitatif deskriptif, sedangkan sumber data yang digunakan ada dua sumber yaitu, data primer dan sekunder. Tekhnik pengumpulan data dalam penelitian dilakukan melalui observasi, wawancara, dan dokumentasi. Penerapan metode tasmi’ di Ma’had Tahfidz Hidayatul Qur’an Desa Puding Besar berhasil diterapkan. Hal ini dapat dilihat dari banyaknya santriwati yang hafal dan mencapai target yang ditentukan, bahkan ada yang melebihi pencapaian target. Begitu pula dengan metode muraja’ah santriwati mampu mentasmi’kan kembali hafalan muraja’ah baik kepada ustadzah pembimbing atau ustadzah penguji ujian tahfidz. Hal ini terbukti dari hasil yang diperoleh santriwati dengan kategori penilaian mumtaz (kesalahan 0-1), jayyid jiddan (kesalahan 2-4), jayyid (kesalahan 5-7), maqbul (kesalahan 8-10), rasib (kesalahan lebih dari sepeluh), dari kelima penilaian tersebut kebanyakan santriwati mendapatkan nilai jayyid jiddan, jayyid, dan mumtaz.
This study aims to determine the application of the tasmi 'and muraja'ah methods in the tahfidzul Qur'an program for female students in Ma'had Tahfidz Hidayatul Qur'an Puding Besar Village and to determine the success of the tahfidzul qur'an program using the tasmi' and muraja 'methods ah to the students at Ma'had Tahfidz Hidayatul Qur'an, Puding Besar Village. The approach used in this research is descriptive qualitative, while the sources of data used are two sources, namely, primary and secondary data. Data collection techniques in research carried out through observation, interviews, and documentation. The application of the tasmi method in Ma'had Tahfidz Hidayatul Qur’an of Puding Besar Village was successfully implemented. This can be seen from the number of female students who memorized and reached the specified target, some even exceeded the target achievement. Similarly, the method of muraja'ah santriwati was able to eradicate the memorization of muraja'ah both to the cleric or the cleric examiner tahfidz. This is evident from the results obtained by female students in the category of mumtaz (error 0-1), jayyid jiddan (error 2-4), jayyid (error 5-7), maqbul (error 8-10), rasib (error more than ten) ), from the five assessments, most students received jayyid jiddan, jayyid, and mumtaz.
Analisis Kesulitan Siswa Dalam Menyelesaikan Soal Sistem Persamaan Linear Dua Variabel Pada Kelas VIII
Authors: Kolo Florensia , Nahak Selestina , Fitriani Fitriani 
Published: January 2022

Tujuan dari penelitian ini adalah untuk mengetahui kesulitan yang dialami siswa dalam menyelesaikan soal sistem persamaan linear dua variabel dan untuk mengetahui faktor - faktor yang menyebabkan siswa kesulitan dalam menyelesaikan soal sistem persamaan linear dua variabel pada kelas VIII SMP Negeri Satap Amol. Metode penelitian yang digunakan adalah deskriptif kualitatif. Subjek penelitian ini adalah siswa kelas VIII A SMP Negeri Satap Amol yang berjumlah 3 orang. Teknik pengumpulan data yang digunakan adalah tes dan wawancara. Instrumen dalam penelitian ini adalah peneliti, soal tes, pedoman wawancara dan dokumentasi. Teknik analisis data dalam penelitian ini adalah mereduksi data, pemaparan data dan menarik kesimpulan. Berdasarkan hasil penelitian, kesulitan yang dialami siswa yaitu kesulitan konsep, kesulitan prinsip dan kesulitan menyelesaikan masalah verbal. Faktor – faktor yang menyebabkan siswa mengalami kesulitan yaitu siswa buru – buru dalam mengerjakan soal, siswa malu bertanya, catatan siswa kurang lengkap, siswa tidak belajar, siswa mengalami kekeliruan dalam mengerjakan soal,siswa tidak memahami dan mengerti, siswa kurang teliti dalam mengerjakan soal,siswa tidak membaca yang diperintahkan pada soal, siswa tidak tau apa yang diketahui dan ditanyakan pada soal.
Pandemik COVID-19: Isu Penggunaan ICT Dalam Proses Pengajaran dan Pembelajaran (PdP) Bagi Pelajar Orang Kurang Upaya (OKU) di Institusi Pendidikan Khas di Malaysia
Authors: Rahman Azman Ab Rahman , Nurul Nadia Nozlan  , Hussein ‘Azeemi Abdullah Thaidi  , Muhammad Firdaus Ab Rahman  , Mohamad Anwar Zakaria  
Published: January 2022

Penggunaan Teknologi Maklumat dan Komunikasi (ICT) pada masa kini semakin mendapat tempat di setiap sektor di Malaysia. Kepesatan pembangunan telah menjadikan ICT itu satu keperluan dalam kalangan orang ramai. Masyarakat tidak kira golongan normal mahupun Orang Kurang Upaya (OKU) tidak ketinggalan dalam menggunakan perkhidmatan ICT yang kian meluas ini. Masyarakat lebih cenderung untuk menggunakan perkhidmatan ICT seperti internet, melakukan transaksi jual beli atas talian (online), melakukan kerja dari rumah (Work From Home) dan proses pembelajaran dari rumah sewaktu PdP. Arahan perintah kawalan pergerakan (PKP) yang telah dilaksanakan oleh kerajaan telah menyebabkan keterbatasan dalam sektor pendidikan untuk beroperasi secara biasa (bersemuka) dan menjadikan pembelajaran secara dalam talian sebagai medium gantian. Namun begitu, timbul persoalan tentang bagaimanakah golongan OKU ini menggunakan medium pengantaraan ICT atau kaedah PdP secara dalam talian sewaktu COVID-19 untuk meneruskan sesi pembelajaran mereka. Justeru, objektif kajian ini adalah untuk mengenalpasti isu yang dihadapi oleh golongan OKU dan institusi pendidikan dalam menggunakan kaedah PdP secara maya dalam proses PdP sewaktu COVID-19. Kajian kualitatif ini akan menggunakan kaedah dokumentasi, temu bual dan pemerhatian dalam mencapai objektif yang ditetapkan. Hasil kajian mendapati bahawa isu utama yang perlu ditempuhi oleh golongan OKU adalah komitmen daripada para pelajar sendiri serta komitmen ibu bapa dalam memantau pembelajaran anak istimewa mereka. Manakala, cabaran yang dihadapi oleh sesebuah institusi pendidikan adalah untuk mengenal pasti kaedah yang sesuai bagi melaksanakan PdP secara dalam talian sewaktu COVID-19 terhadap pelajar daripada golongan OKU. Kajian ini diharapkan dapat menjadi rujukan kepada institusi pendidikan dalam menambah baik proses PdP bagi pelajar OKU sewaktu bencana berlaku seperti COVID-19 ini.
Modification of Frozen Elephant Trunk Technique for Acute Type-A Aortic Dissection - A Case Report
Authors: Gupta Saikat Das , Chanda PK , Adhikary DK 
Published: January 2022

Acute type-A aortic dissection (ATAAD) is a dreadfully fatal cardiovascular emergency. The mortality rate among medically treated patients is 50% within two days. Surgery is the gold standard and urgent surgical treatment is indicated for all patients, except for those who are moribund or severely comorbid. However, early mortality after operation remains high (9–25%). We hereby present a case of 22 years young, male, Marfan patient with a family history of ATAAD treated successfully by us at Square Hospital Ltd by modified Bentall’s procedure with total arch replacement with Frozen Elephant Trunk (FET) technique.
University Heart Journal 2022; 18(1): 65-70
Pathogenic Variations of Homologous Recombination Gene HSF2BP Identified in Sporadic Patients With Premature Ovarian Insufficiency
Authors: Li Shan , Xu Weiwei , Xu Bingying , Gao Shuchang , Zhang Qian , Qin Yingying , Guo Ting 
Published: January 2022

Premature ovarian insufficiency (POI) is defined as depletion of ovarian function before 40 years of age, which affects 3.7% of women in reproductive age. The etiology of POI is heterogeneous. Recently, with the widespread use of whole-exome sequencing (WES), the DNA repair genes, especially for those involved in meiosis progress, were enriched in the causative gene spectrum of POI. In this study, through the largest in-house WES database of 1,030 patients with sporadic POI, we identified two novel homozygous variations in HSF2BP (c.382T&gt;C, p.C128R; c.557T&gt;C, p.L186P). An in vitro functional study revealed that both variations impaired the nuclear location of HSF2BP and affected its DNA repair capacity. Our studies highlighted the essential role of meiotic homologous recombination genes in the pathogenesis of sporadic POI.
Identification of Prognostic Biomarkers for Bladder Cancer Based on DNA Methylation Profile
Authors: Zhang Shumei , Zhang Jingyu , Zhang Qichao , Liang Yingjian , Du Youwen , Wang Guohua 
Published: January 2022

Background: DNA methylation is an important epigenetic modification, which plays an important role in regulating gene expression at the transcriptional level. In tumor research, it has been found that the change of DNA methylation leads to the abnormality of gene structure and function, which can provide early warning for tumorigenesis. Our study aims to explore the relationship between the occurrence and development of tumor and the level of DNA methylation. Moreover, this study will provide a set of prognostic biomarkers, which can more accurately predict the survival and health of patients after treatment.Methods: Datasets of bladder cancer patients and control samples were collected from TCGA database, differential analysis was employed to obtain genes with differential DNA methylation levels between tumor samples and normal samples. Then the protein-protein interaction network was constructed, and the potential tumor markers were further obtained by extracting Hub genes from subnet. Cox proportional hazard regression model and survival analysis were used to construct the prognostic model and screen out the prognostic markers of bladder cancer, so as to provide reference for tumor prognosis monitoring and improvement of treatment plan.Results: In this study, we found that DNA methylation was indeed related with the occurrence of bladder cancer. Genes with differential DNA methylation could serve as potential biomarkers for bladder cancer. Through univariate and multivariate Cox proportional hazard regression analysis, we concluded that FASLG and PRKCZ can be used as prognostic biomarkers for bladder cancer. Patients can be classified into high or low risk group by using this two-gene prognostic model. By detecting the methylation status of these genes, we can evaluate the survival of patients.Conclusion: The analysis in our study indicates that the methylation status of tumor-related genes can be used as prognostic biomarkers of bladder cancer.
HBeAg Is Indispensable for Inducing Liver Sinusoidal Endothelial Cell Activation by Hepatitis B Virus
Authors: Xie Xiaohong , Luo Jinzhuo , Zhu Dan , Zhou Wenqing , Yang Xuecheng , Feng Xuemei , Lu Mengji , Zheng Xin , Dittmer Ulf , Yang Dongliang , Liu Jia 
Published: January 2022

Background and AimsLiver sinusoidal endothelial cells (LSECs) serve as sentinel cells to detect microbial infection and actively contribute to regulating immune responses for surveillance against intrahepatic pathogens. We recently reported that hepatitis B e antigen (HBeAg) stimulation could induce LSEC maturation and abrogate LSEC-mediated T cell suppression in a TNF-α and IL27 dependent manner. However, it remains unclear how HBeAg deficiency during HBV infection influences LSEC immunoregulation function and intrahepatic HBV-specific CD8 T cell responses.MethodsThe function of LSECs in regulating effector T cell response, intrahepatic HBV-specific CD8 T cell responses and HBV viremia were characterized in both HBeAg-deficient and -competent HBV hydrodynamic injection (HDI) mouse models.ResultsLSECs isolated from HBeAg-deficient HBV HDI mice showed a reduced capacity to promote T cell immunity in vitro compared with those isolated from wild-type HBV HDI mice. HBeAg expression replenishment in HBeAg-deficient HBV HDI mice restored the HBV-induced LSEC maturation, and resulted in potent intrahepatic anti-HBV CD8 T cell responses and efficient control of HBV replication. Moreover, in vivo TNF-α, but not IL27 blockade in HBV HDI mice impaired HBV-specific CD8 T cell immunity and delayed HBV clearance.ConclusionOur study underlines that HBeAg is indispensable for HBV-induced LSEC maturation to trigger intrahepatic HBV-specific T cell activation, and provides a new mechanism to elucidate the intrahepatic immune microenvironment regulation upon HBV exposure.